Variant translocations in two Burkitt's lymphoma cell lines are located in the MLV14 locus.
The human MLV14 locus, located 20 kilobases 3' of MYC, is rearranged in two Burkitt's lymphoma cell lines with either a t(2;8)(p12;q24) or t(8;22)(q24;q11). Alterations of MLV14 may have prognostic significance in some types of B-cell malignancies.
Gallego
M I
MI
Unidad de Genética Molecular, Instituto de Salud Carlos III, Majadahonda, Spain.
Lazo
P A
PA
D015139:Blotting, Southern; D002051:Burkitt Lymphoma / Q000235:genetics*; D002889:Chromosomes, Human, Pair 2; D002892:Chromosomes, Human, Pair 22; D002898:Chromosomes, Human, Pair 8; D016259:Genes, myc / Q000235:genetics; D005819:Genetic Markers / Q000235:genetics; D006801:Humans; D011379:Prognosis; D014178:Translocation, Genetic / Q000235:genetics*; D014407:Tumor Cells, Cultured
D005819:Genetic Markers