[The capacity of purified staphylococcal anatoxin to correct antigen-specific and antigen-nonspecific immunological defects].
Purified staphylococcal toxoid is capable of partially preventing the development of antigen-specific (induced by the supraoptimal dose of sheep red blood cells) and antigen-nonspecific (induced by Tahyna virus) defects of humoral immune response, as well as abolishing these defects. The presence and manifestation of the correction of virus-induced immunodeficiency is determined by the dose of the toxoid and the interval between the injections of purified staphylococcal toxoid and the infective agent.
Semenova
I B
IB
Vargin
V V
VV
Akatov
A K
AK
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects / Q000276:immunology; D004306:Dose-Response Relationship, Immunologic; D004353:Drug Evaluation, Preclinical; D002141:Encephalitis Virus, California; D004670:Encephalitis, California / Q000209:etiology / Q000276:immunology / Q000628:therapy*; D000939:Epitopes / Q000187:drug effects* / Q000276:immunology; D007154:Immune System Diseases / Q000209:etiology / Q000276:immunology / Q000628:therapy*; D007114:Immunization / Q000379:methods; D051379:Mice; D008808:Mice, Inbred CBA; D013208:Staphylococcal Toxoid / Q000302:isolation & purification / Q000627:therapeutic use*; D013997:Time Factors
D000939:Epitopes; D013208:Staphylococcal Toxoid