title: Role of magnetic resonance imaging in the evaluation of the hydroxyapatite orbital implant.
abstract: The role of magnetic resonance imaging (MRI) in the assessment of fibrovascular ingrowth in the integrated hydroxyapatite orbital implant is evaluated. Fifteen patients who underwent enucleation and placement of a hydroxyapatite orbital implant were evaluated for degree of implant vascularity with gadolinium-DPTA-enhanced MRI with surface coil before drilling the implant. On T1-weighted images, the hydroxyapatite sphere appeared with intermediate signal. After gadolinium-DPTA administration, all patients showed an enhancement in the implant consistent with the presence of fibrovascular ingrowth. The enhancement was most notable in the peripheral portions of the sphere and was seen as early as 5 months after implantation. Comparison of gadolinium-DPTA-enhanced MRI with contrast-enhanced computed tomography, ultrasonography, and color Doppler imaging suggests that these latter techniques are not as helpful in the detection of the fibrovascular tissue in the orbital implant. Bone scan, a technique used by many surgeons, demonstrates fibrovascular ingrowth, but it is limited by its one-dimensional low-resolution image. Because of its three-dimensional capability and its highest resolution, contrast-enhanced MRI with surface coil appears to be the best imaging method for evaluating the hydroxyapatite orbital implant and its fibrovascular ingrowth.
authors.affiliation: Oncology Service, Wills Eye Hospital, Philadelphia, PA 19107.
authors.forename: P
authors.initials: P
authors.lastname: De Potter
authors.forename: C L
authors.initials: CL
authors.lastname: Shields
authors.forename: J A
authors.initials: JA
authors.lastname: Shields
authors.forename: A E
authors.initials: AE
authors.lastname: Flanders
authors.forename: V M
authors.initials: VM
authors.lastname: Rao
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003287:Contrast Media; D017886:Durapatite; D015353:Eye Enucleation; D005260:Female; D005355:Fibrosis / Q000175:diagnosis; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D006882:Hydroxyapatites; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000175:diagnosis; D009915:Orbit / Q000000981:diagnostic imaging*; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019736:Prostheses and Implants; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D003287:Contrast Media; D006882:Hydroxyapatites; D009942:Organometallic Compounds; D004369:Pentetic Acid; D017886:Durapatite; D005682:Gadolinium; D019786:Gadolinium DTPA