title: Parathyroid hormone activation of stretch-activated cation channels in osteosarcoma cells (UMR-106.01).
abstract: Cell-attached patches of membrane of osteoblast-like cells UMR-106.01 respond to bath application of parathyroid hormone (PTH) with an increase in the average activity, as well as the single channel conductance, of a stretch-activated non-selective cation channel. Correlations with whole cell membrane potential and conductance changes are considered.
authors.affiliation: Department of Medicine, Jewish Hospital, Washington University Medical Center, St. Louis, MO 63110.
authors.forename: R L
authors.initials: RL
authors.lastname: Duncan
authors.forename: K A
authors.initials: KA
authors.lastname: Hruska
authors.forename: S
authors.initials: S
authors.lastname: Misler
mesh_terms: D000818:Animals; D004553:Electric Conductivity; D015640:Ion Channel Gating / Q000502:physiology*; D007473:Ion Channels / Q000502:physiology*; D008465:Mechanoreceptors / Q000502:physiology; D012516:Osteosarcoma; D010281:Parathyroid Hormone / Q000502:physiology*; D051381:Rats; D014407:Tumor Cells, Cultured
chemical_list: D007473:Ion Channels; D010281:Parathyroid Hormone