title: A point mutation in a Shaker K+ channel changes its charybdotoxin binding site from low to high affinity.
authors.affiliation: Howard Hughes Medical Institute, Graduate Department of Biochemistry, Brandeis University, Waltham, Massachusetts 02254-9110.
authors.forename: S A
authors.initials: SA
authors.lastname: Goldstein
authors.forename: C
authors.initials: C
authors.lastname: Miller
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D055592:Biophysical Phenomena; D001703:Biophysics; D018999:Charybdotoxin; D005260:Female; D007700:Kinetics; D008969:Molecular Sequence Data; D009154:Mutation; D009865:Oocytes / Q000378:metabolism; D015221:Potassium Channels / Q000235:genetics* / Q000378:metabolism; D012604:Scorpion Venoms / Q000378:metabolism*; D014981:Xenopus
chemical_list: D015221:Potassium Channels; D012604:Scorpion Venoms; D018999:Charybdotoxin