title: Cardiac rupture after thrombolytic therapy: the use of aprotinin to reduce blood loss after surgical repair.
abstract: Emergency cardiac surgery after recent thrombolytic therapy is associated with increased blood loss. A patient underwent emergency repair of a ruptured left ventricle after intravenous streptokinase treatment for acute coronary occlusion. High dose aprotinin was given during the operation to reduce the expected blood loss. Surgical repair was successful without bleeding complications. Total postoperative blood loss was 365 ml.
authors.affiliation: Cardiothoracic Surgery and Medical Cardiology, General Infirmary, Leeds.
authors.forename: C A
authors.initials: CA
authors.lastname: van Doorn
authors.forename: C M
authors.initials: CM
authors.lastname: Munsch
authors.forename: J C
authors.initials: JC
authors.lastname: Cowan
mesh_terms: D000368:Aged; D007611:Aprotinin / Q000627:therapeutic use*; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D004630:Emergencies; D005260:Female; D006342:Heart Rupture, Post-Infarction / Q000209:etiology / Q000601:surgery*; D006801:Humans; D013300:Streptokinase / Q000009:adverse effects; D015912:Thrombolytic Therapy / Q000009:adverse effects*
chemical_list: D007611:Aprotinin; D013300:Streptokinase