title: A clinical trial to reduce the rate of low birth weight in an inner-city black population.
abstract: BACKGROUND
  The goal of our study was to measure the effectiveness of a home-based intervention for prevention of low birth weight with 154 high-risk, low-income black women attending a prenatal clinic in Cleveland.
  
  
  METHODS
  Based on previous research, risk was defined by clinic registration between the 17th and 28th weeks of gestation, low family functioning score, and experience of at least one stressful life event prior to registration. Optional factors included being a smoker, a low maternal weight-height ratio, being age 27 or older, and a previous premature birth. A 21-item family function screen previously validated in a similar population was the primary determinant of psychosocial risk. Low birth weight was defined as weight less than 2,500 g regardless of gestational age.
  
  
  RESULTS
  There was no decrease in the rate of low birth weight for women who received four home visits focusing on smoking, drug and nutrition education, support, and links with community services, compared to women who received no visits. The number of prenatal visits was significantly higher in the intervention group, but an increased number of prenatal visits did not correlate with a reduced rate of low birth weight. Despite previous research, the family function screen was not an effective predictor of low birth weight in our study. A revised equation involving a history of previous premature birth, smoking, and a low maternal weight-height ratio did predict low birth weight.
  
  
  CONCLUSIONS
  These findings question the utility of short-term psychosocial interventions for influencing low birth-weight rates in low-income black clinic populations. The family function screen was not cross validated. Integration of any psychosocial intervention with the routine prenatal care occurring in the obstetrical clinic is suggested for future research.
authors.affiliation: Department of Family Medicine, Case Western Reserve University.
authors.forename: A V
authors.initials: AV
authors.lastname: Graham
authors.forename: S H
authors.initials: SH
authors.lastname: Frank
authors.forename: S J
authors.initials: SJ
authors.lastname: Zyzanski
authors.forename: G C
authors.initials: GC
authors.lastname: Kitson
authors.forename: K G
authors.initials: KG
authors.lastname: Reeb
mesh_terms: D000293:Adolescent; D000328:Adult; D001741:Black or African American; D005260:Female; D006699:Home Care Services; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D009820:Ohio; D011247:Pregnancy; D011256:Pregnancy Outcome; D011295:Prenatal Care / Q000458:organization & administration*; D011446:Prospective Studies; D012107:Research Design; D012307:Risk Factors; D014505:Urban Population