A marine algal Na(+)-activated ATPase possesses an immunologically identical epitope to Na+,K(+)-ATPase.
Immunological homology was investigated between Heterosigma akashiwo (a marine algae) Na(+)-activated ATPase and animal Na+,K(+)-ATPase. The former polypeptide [(1989) Plant Cell Physiol. 30, 923-928] reacted with anti-serum raised against the amino-terminal half of the pig kidney Na+,K(+)-ATPase alpha subunit. It is suggested that the Na+,K(+)-ATPase epitope within the amino-terminal region is conserved in the plant Na(+)-activated ATPase, and the region containing the epitope may be important for Na ion transport.
Wada
M
M
Institute of Biological Sciences, University of Tsukuba, Ibaraki, Japan.
Urayama
O
O
Satoh
S
S
Hara
Y
Y
Ikawa
Y
Y
Fujii
T
T
D000906:Antibodies / Q000276:immunology; D001665:Binding Sites; D003429:Cross Reactions; D000939:Epitopes / Q000276:immunology*; D056890:Eukaryota / Q000201:enzymology*; D015151:Immunoblotting; D012964:Sodium / Q000378:metabolism*; D000254:Sodium-Potassium-Exchanging ATPase / Q000276:immunology* / Q000378:metabolism
D000906:Antibodies; D000939:Epitopes; D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase