title: Effect of marrow perforation on the sheep temporomandibular joint.
abstract: The effect of surgically perforating the mandibular condyle to allow synovial fluid to contact the marrow was examined in 5 sheep temporomandibular joints. The surgical defect showed replacement of the marrow with fibro-osseous tissue and subcortical cysts. A vertical, central osteophyte emerged from the perforation, causing attenuation or perforation of the disc and temporal surface proliferation. These changes were radiographically and histologically similar to advanced osteoarthritis. This supports the concept that intraarticular micro or macrofracture may result in osteoarthritis.
authors.affiliation: Department of Stomatology, Gifu Municipal Hospital, Japan.
authors.forename: J I
authors.initials: JI
authors.lastname: Ishimaru
authors.forename: K
authors.initials: K
authors.lastname: Kurita
authors.forename: Y
authors.initials: Y
authors.lastname: Handa
authors.forename: A N
authors.initials: AN
authors.lastname: Goss
mesh_terms: D000818:Animals; D001845:Bone Cysts / Q000473:pathology; D001853:Bone Marrow / Q000473:pathology*; D016723:Bone Remodeling; D002358:Cartilage, Articular / Q000473:pathology; D003238:Connective Tissue / Q000473:pathology; D008335:Mandibular Condyle / Q000473:pathology*; D010003:Osteoarthritis / Q000473:pathology; D010012:Osteogenesis; D010026:Osteosclerosis / Q000473:pathology; D012756:Sheep; D013582:Synovial Fluid / Q000502:physiology*; D000267:Tissue Adhesions / Q000473:pathology