Retinoids and contraception.
The main side effect of the retinoids is teratogenicity. Every dermatologist has a moral obligation to ensure that this effect is avoided, and the present publication is aimed at helping prescribe these drugs. After a review of the key properties of each of the retinoids on the market, the different forms of contraception available and their indication in young patients undergoing retinoid treatment are discussed. Unless otherwise contraindicated, oral contraception with an estrogen-progestogen formulation is the contraceptive method of choice for women undergoing retinoid treatment. The intrauterine device (IUD) is of little or almost no relevance for young women undergoing treatment with a retinoid. IUDs are indicated in older multiparae who have practised this form of contraception before starting retinoid treatment and who refuse to take the pill. Natural and local methods of contraception are totally unsuitable for women undergoing treatment with retinoids. However, they may be used as an additional precautionary measure by IUD users.
Ceyrac
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Service du Pr. Puissant, Hôpital Saint-Louis, Paris, France.
Serfaty
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D
Lefrancq
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H
D000014:Abnormalities, Drug-Induced / Q000517:prevention & control; D000152:Acne Vulgaris / Q000188:drug therapy; D000328:Adult; D003267:Contraception / Q000379:methods*; D003276:Contraceptives, Oral / Q000494:pharmacology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007434:Intrauterine Devices; D008875:Middle Aged; D011247:Pregnancy; D012176:Retinoids / Q000009:adverse effects / Q000493:pharmacokinetics
D003276:Contraceptives, Oral; D012176:Retinoids