title: Hemiparesis in HIV infection. Rehabilitation approach.
abstract: Persons with acquired immunodeficiency syndrome (AIDS) and human immunodeficiency virus (HIV) infection demonstrate a wide array of central nervous system impairments and may be at a significantly increased risk for cerebrovascular disease. Cerebrovascular disease can be the first manifestation of HIV infection and may be associated with a treatable etiology. Anticipating more referrals for HIV-related physical disability, we detail the rehabilitation management of three persons with HIV infection and hemiparesis. Onset of hemiparesis ranged from just before to 24 months after an AIDS-defining illness. No specific underlying etiology was identified in two of three patients, consistent with previous observations. Rehabilitation interventions included lower and upper extremity orthoses, assistive devices to aid gait and activities of daily living, therapeutic exercise and use of antispasticity medication. All patients made at least mild, temporary gains in functional status. Survival ranged from 3 to >6 months from initial contact with rehabilitation services. Neurologic and nonneurologic considerations in the rehabilitation of persons with HIV infection are discussed. We conclude that selected individuals with HIV infection and hemiparesis can benefit from rehabilitation intervention. HIV infection should be considered in any young adult presenting with stroke.
authors.affiliation: Department of Physical Medicine and Rehabilitation, University of Cincinnati College of Medicine (M.W.O.) 45267-0530.
authors.forename: M W
authors.initials: MW
authors.lastname: O'Dell
authors.forename: N L
authors.initials: NL
authors.lastname: Sasson
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D001921:Brain / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000150:complications*; D006679:HIV Seropositivity / Q000150:complications*; D006429:Hemiplegia / Q000175:diagnosis / Q000209:etiology* / Q000534:rehabilitation*; D006801:Humans; D007968:Leukoencephalopathy, Progressive Multifocal / Q000150:complications* / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed