Biology of inherited coagulopathies: von Willebrand factor.
von Willebrand disease is a common inherited bleeding disorder due to qualitative or quantitative abnormalities in von Willebrand factor. This article reviews the progress that has been made over the past few years in defining the molecular basis of von Willebrand disease. It should soon be possible to precisely diagnose and classify many cases of von Willebrand disease using modern genetic techniques.
Ginsburg
D
D
Department of Internal Medicine, Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor.
D005315:Fetal Diseases / Q000175:diagnosis; D005796:Genes; D006801:Humans; D009154:Mutation; D011296:Prenatal Diagnosis; D015995:Prevalence; D014842:von Willebrand Diseases / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics*; D014841:von Willebrand Factor / Q000235:genetics*
D014841:von Willebrand Factor