[Interferon-inducing activity of hydroxybenzylamine derivative].
Interferon-inducing activity of the interferon inductor savrats, an oxybenzylamine derivative of was studied. It was shown on experimental animals that along with its low toxicity, savrats had a high interferon inducing capacity. There were early and late peaks of interferon production (4-8 and 48-96 hours later, respectively) depending on the route of the inductor administration. It was noted that for optimization of the schemes for using interferon inductors, careful choosing of the drug pairs participating in the induction and employment of various routes for administration of the same drug are required.
Saĭitkulov
A M
AM
Ershov
F I
FI
Aslanov
Kh A
KhA
Tazulakhova
E B
EB
Maulianov
S A
SA
D000284:Administration, Oral; D000285:Administration, Rectal; D000818:Animals; D001596:Benzylamines / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D007273:Injections, Intramuscular; D007274:Injections, Intraperitoneal; D007369:Interferon Inducers / Q000494:pharmacology*; D007372:Interferons / Q000096:biosynthesis*; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D008954:Models, Biological; D013997:Time Factors
D001596:Benzylamines; D007369:Interferon Inducers; D007372:Interferons