Binding of laminin, type IV collagen, and vitronectin by Streptococcus pneumoniae.
Forty-three strains of Streptococcus pneumoniae were tested for their ability to bind radiolabelled laminin, collagen types I, II and IV, fibronectin, and vitronectin. Two basement membrane components, laminin and type IV collagen, interacted with many S. pneumoniae strains. All strains bound laminin and 28 (65%) bound collagen type IV. Approximately 60% of the strains bound vitronectin but only a few strains showed low binding of fibronectin and collagen type I and II.
Kostrzynska
M
M
Department of Medical Microbiology, University of Lund, Sweden.
Wadström
T
T
D001422:Bacterial Adhesion; D003094:Collagen / Q000737:chemistry*; D006023:Glycoproteins / Q000737:chemistry*; D007797:Laminin / Q000737:chemistry*; D011485:Protein Binding; D013290:Streptococcal Infections / Q000382:microbiology; D013296:Streptococcus pneumoniae / Q000502:physiology*; D019096:Vitronectin
D006023:Glycoproteins; D007797:Laminin; D019096:Vitronectin; D003094:Collagen