title: Cloning and functional expression of a cDNA encoding the mouse beta 2 subunit of the kainate-selective glutamate receptor channel.
abstract: The primary structure of the mouse glutamate receptor beta 2 subunit has been deduced by cloning and sequencing cDNA. The beta 2 subunit has structural characteristics common to the subunits of glutamate-gated ion channels. Expression of the cloned cDNA in Xenopus oocytes yields functional glutamate receptor channels selective for kainate.
authors.affiliation: Department of Neuropharmacology, Faculty of Science, Niigata University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Morita
authors.forename: K
authors.initials: K
authors.lastname: Sakimura
authors.forename: E
authors.initials: E
authors.lastname: Kushiya
authors.forename: M
authors.initials: M
authors.lastname: Yamazaki
authors.forename: H
authors.initials: H
authors.lastname: Meguro
authors.forename: K
authors.initials: K
authors.lastname: Araki
authors.forename: T
authors.initials: T
authors.lastname: Abe
authors.forename: K J
authors.initials: KJ
authors.lastname: Mori
authors.forename: M
authors.initials: M
authors.lastname: Mishina
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D004247:DNA / Q000235:genetics*; D015870:Gene Expression; D005971:Glutamates / Q000494:pharmacology; D018698:Glutamic Acid; D007473:Ion Channels / Q000187:drug effects / Q000235:genetics*; D007608:Kainic Acid / Q000494:pharmacology; D051379:Mice / Q000235:genetics*; D008813:Mice, Inbred ICR / Q000235:genetics; D008969:Molecular Sequence Data; D016318:Quisqualic Acid / Q000494:pharmacology; D018092:Kainic Acid Receptors; D017981:Receptors, Neurotransmitter / Q000096:biosynthesis / Q000187:drug effects / Q000235:genetics*; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis*; D012689:Sequence Homology, Nucleic Acid; D014982:Xenopus laevis
chemical_list: D004247:DNA; D005971:Glutamates; D018698:Glutamic Acid; D007473:Ion Channels; D007608:Kainic Acid; D016318:Quisqualic Acid; D018092:Kainic Acid Receptors; D017981:Receptors, Neurotransmitter; D011993:Recombinant Fusion Proteins