Biochemical analysis of MHC and non-MHC lymphocyte membrane antigens.
Basic biochemical techniques have been skillfully used to characterize MHC-bound peptides and to examine the changes that occur in MHC molecules and lymphocyte membrane receptor complexes upon ligand binding. The fine tuning of these experimental approaches was possible because of the availability of a variety of biochemical and biological reagents.
Yang
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Memorial Sloan-Kettering Cancer Center, New York, New York.
D000345:Affinity Labels; D000818:Animals; D000954:Antigens, Surface / Q000032:analysis*; D002623:Chemistry Techniques, Analytical; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D000939:Epitopes / Q000032:analysis; D006649:Histocompatibility Antigens / Q000032:analysis*; D008214:Lymphocytes / Q000737:chemistry*; D011499:Protein Processing, Post-Translational; D015398:Signal Transduction
D000345:Affinity Labels; D000954:Antigens, Surface; D000939:Epitopes; D006649:Histocompatibility Antigens