title: Cryosurgery for locally recurrent rectal cancer.
abstract: Locally recurrent rectal cancer is, in most cases, unresectable and incurable. Palliative treatment is warranted in many cases because of the presence of severe distressing symptoms. In recurrent disease, intraluminal cryotherapy is an option for palliation. Twenty patients with local recurrence after anterior resection were treated palliatively with cryosurgery for their local symptoms. Six patients had previously had a colostomy before they were referred for palliative treatment. Thirteen patients had more than one symptom. Distant metastases were present in ten cases. The beneficial effect of cryosurgery was evident after two to three sessions. In nine patients cryotherapy achieved complete relief of local symptoms. In these patients the symptom free interval varied from 1 to 24 months (median 11 months); five patients died of disease without local symptoms. Three of these nine patients underwent a bowel diversion at a later stage because of complete stenosis. The number of treatment sessions in this group of patients varied from three to 14. The palliative index varied from 37 to 100% (mean 78%). In nine patients cryotherapy of the local recurrence gave no relief at all. Our results show that in almost half of the patients cryosurgery can palliate local complaints resulting from recurrent tumor growth after anterior resection.
authors.affiliation: Department of Surgery, Free University Hospital, Amsterdam, The Netherlands.
authors.forename: S
authors.initials: S
authors.lastname: Meijer
authors.forename: P D
authors.initials: PD
authors.lastname: de Rooij
authors.forename: E J
authors.initials: EJ
authors.lastname: Derksen
authors.forename: H
authors.initials: H
authors.lastname: Boutkan
authors.forename: M A
authors.initials: MA
authors.lastname: Cuesta
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003452:Cryosurgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D010166:Palliative Care / Q000379:methods*; D012004:Rectal Neoplasms / Q000473:pathology / Q000601:surgery*