title: Effect of angiotensin II and atrial natriuretic factor on neurons in the subfornical organ of ducks and rats in vitro.
abstract: Atrial natriuretic factor (ANF) antagonizes many angiotensin II (ANGII)-induced effects on osmoregulatory relevant parameters in vivo. In this study ANF analogues decreased the spontaneous and the ANGII-induced electrical activity of subfornical organ (SFO) neurons in rats, but had no effect on ANGII sensitive or insensitive SFO neurons in ducks. These results suggest a more distinct functional separation for the responsiveness to ANGII and ANF in birds compared to mammals.
authors.affiliation: Max-Planck-Institut für physiologische und klinische Forschung, W.G. Kerckhoff-Institut, Bad Nauheim, FRG.
authors.forename: H A
authors.initials: HA
authors.lastname: Schmid
authors.forename: E
authors.initials: E
authors.lastname: Simon
mesh_terms: D000200:Action Potentials / Q000187:drug effects; D000804:Angiotensin II / Q000494:pharmacology*; D000818:Animals; D009320:Atrial Natriuretic Factor / Q000494:pharmacology*; D001345:Autoradiography; D004372:Ducks / Q000502:physiology*; D005260:Female; D007700:Kinetics; D008297:Male; D009474:Neurons / Q000187:drug effects*; D051381:Rats; D013356:Subfornical Organ / Q000166:cytology / Q000187:drug effects*; D014882:Water-Electrolyte Balance / Q000187:drug effects
chemical_list: D000804:Angiotensin II; D009320:Atrial Natriuretic Factor