Bovine Escherichia coli of serotypes O55:H4 and O55:H21 which produce CNF2 express P fimbriae and Vir surface antigen, respectively.
We have characterized the toxic and adhesive properties of Escherichia coli strains producing the second type of cytotoxic necrotizing factor (CNF2) and belonging to the classic enteropathogenic serogroup O55. Bovine CNF2 strains of serotype O55:H4 express P fimbriae as do pyelonephritic Escherichia coli that cause infections in humans. In contrast, strains of serotype O55:H21 which produce CNF2 from bovine origin possess the Vir surface antigen. One human strain of serotype O55:H- was positive for production of CNF2, but was negative for the two adhesive factors and for mannose-resistant haemagglutination.
Blanco
J
J
Departamento de Microbioloxía e Parasitoloxía, Facultade de Veterinaria, Universidade de Santiago, Lugo, Spain.
Blanco
M
M
González
E A
EA
Garabal
J I
JI
Blanco
J E
JE
Jansen
W H
WH
D000818:Animals; D001427:Bacterial Toxins / Q000378:metabolism*; D002417:Cattle; D003603:Cytotoxins / Q000378:metabolism*; D004926:Escherichia coli / Q000276:immunology / Q000378:metabolism / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000382:microbiology; D029968:Escherichia coli Proteins; D010861:Fimbriae, Bacterial / Q000378:metabolism*; D006367:HeLa Cells; D006801:Humans; D008565:Membrane Proteins / Q000032:analysis*; D019081:O Antigens; D011135:Polysaccharides, Bacterial / Q000378:metabolism*; D014774:Virulence
D001427:Bacterial Toxins; D003603:Cytotoxins; D029968:Escherichia coli Proteins; D008565:Membrane Proteins; D019081:O Antigens; D011135:Polysaccharides, Bacterial; C060296:cytotoxic necrotizing factor type 1