[Clinico-immunological aspects of idiopathic ventricular arrhythmia].
The clinicoimmunological study revealed immunocompetence dysfunction in 28 patients with idiopathic ventricular arrhythmias resistant to ritmilen. After sodium nucleinate immunomodulation, ritmilen therapy proved to be beneficial in 46.6% of the patients. A positive result was obtained only in the patients who showed the same or close values as in healthy individuals. The comparison has led to the conclusion that idiopathic ventricular arrhythmias are directly related to immune dysfunction and to the recommendation that sodium nucleinate should be used in the multimodality therapy of the arrhythmias.
Nikitin
A V
AV
Zemskov
A M
AM
Zemskov
V M
VM
Gusmanov
V A
VA
D000276:Adjuvants, Immunologic; D000328:Adult; D001402:B-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D005117:Cardiac Complexes, Premature / Q000188:drug therapy / Q000276:immunology*; D004206:Disopyramide / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007958:Leukocyte Count / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D009696:Nucleic Acids / Q000008:administration & dosage; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology*
D000276:Adjuvants, Immunologic; D009696:Nucleic Acids; C013683:sodium nucleinate; D004206:Disopyramide