title: Pseudomonas cepacia pulmonary infection in adults with cystic fibrosis: is nosocomial acquisition occurring?
abstract: Ribotyping of 25 isolates of Pseudomonas cepacia taken from the sputum of 21 adults with cystic fibrosis (CF) who were registered at the Royal Brompton Hospital between 1987 and 1991, revealed that seven patients (33.3%) shared strains of a similar ribotype pattern with others, while 14 patients (63.7%) harboured strains unique to each individual. Constancy of sputum strain carriage was seen in two of three patients sampled twice over a 3-month period. Although no evidence for patient-to-patient transmission of P. cepacia within this group of patients was found, the fact that one third of CF patients shared strains of the same ribotype with others, suggests that nosocomial acquisition of this organism may have occurred.
authors.affiliation: Department of Cystic Fibrosis, Royal Brompton Hospital, London, UK.
authors.forename: R F
authors.initials: RF
authors.lastname: Taylor
authors.forename: L
authors.initials: L
authors.lastname: Dalla Costa
authors.forename: M E
authors.initials: ME
authors.lastname: Kaufmann
authors.forename: T L
authors.initials: TL
authors.lastname: Pitt
authors.forename: M E
authors.initials: ME
authors.lastname: Hodson
mesh_terms: D000293:Adolescent; D000328:Adult; D015373:Bacterial Typing Techniques; D016956:Burkholderia cepacia / Q000145:classification / Q000302:isolation & purification*; D003428:Cross Infection / Q000382:microbiology / Q000635:transmission*; D003550:Cystic Fibrosis / Q000150:complications / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D011552:Pseudomonas Infections / Q000382:microbiology / Q000635:transmission*; D012141:Respiratory Tract Infections / Q000382:microbiology / Q000635:transmission*