[Effect of Salvia miltiorrhiza on the cardial ischemia in rats induced by ligation].
I.p. injection (5 g crude drug/kg) of water extract of Salvia miltiorrhiza to S.D. rats can prevent the acute cardial ischemia induced by the ligation of the coronary artery. The elevation of S-T segment in the electrocardiogram caused by the ischemia was greatly reduced in animals treated with Salvia miltiorrhiza compared with control group. The ischemia area in the left ventricle was significantly reduced and survival rate of the rats increased.
Cheng
Y Y
YY
Chinese Medicinal Material Research Centre, Chinese University of Hong Kong.
Fong
S M
SM
Hon
P M
PM
D000818:Animals; D003327:Coronary Disease / Q000517:prevention & control*; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004562:Electrocardiography / Q000187:drug effects; D008297:Male; D010618:Phenanthrolines / Q000627:therapeutic use*; D010936:Plant Extracts; D051381:Rats; D017207:Rats, Sprague-Dawley; D027561:Salvia miltiorrhiza
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D010618:Phenanthrolines; D010936:Plant Extracts; C028972:dan-shen root extract