Secretion of metalloproteases by living infective larvae of Necator americanus.
Fresh living third-stage larvae of Necator americanus released a significant amount of label within 2 hr of their incubation on 125I-labeled gelatin-coated polystyrene plastic plates. This protease activity was primarily susceptible to o-phenanthroline, which identifies the activity as predominantly metalloprotease.
Kumar
S
S
Department of Life Science, University of Nottingham, University Park, England.
Pritchard
D I
DI
D000818:Animals; D002850:Chromatography, Gel; D006224:Cricetinae; D005780:Gelatin / Q000378:metabolism; D007814:Larva / Q000201:enzymology; D008666:Metalloendopeptidases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D017221:Necator americanus / Q000201:enzymology*
D005780:Gelatin; D008666:Metalloendopeptidases