Antibacterial and antiproliferative activities of vulpinic acids in vitro.
The antimicrobial and antiproliferative activities of vulpinic acids (1 a, b, c) have been assayed in vitro. Activity was demonstrated by vulpinic acids on Gram-positive bacteria only. The MIC values of these compounds were found to be ranging from 3.8-31.5 micrograms/ml. The significance of these results is discussed.
Nadir
M T
MT
Al-Mansour Technical Institute, Baghdad, Iraq.
Rashan
L J
LJ
Ayoub
M T
MT
Awni
L T
LT
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D005663:Furans / Q000494:pharmacology*; D006094:Gram-Positive Bacteria / Q000187:drug effects; D051379:Mice; D008826:Microbial Sensitivity Tests; D010648:Phenylacetates / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D005663:Furans; D010648:Phenylacetates; C077134:vulpinic acid