title: Nosocomial bacterial infections among children with severe protein energy malnutrition.
abstract: The incidence of hospital acquired acute bacterial infections among 164 severely malnourished children admitted to the paediatric wards at the Muhimbili Medical Centre in Dar es Salaam were studied. On admission, ninety two per cent of the patients had at least one form of bacterial infection. During the subsequent two weeks hospital stay, 49% of the patients acquired a new infection. Septicaemia and urinary tract infection (UTI) were the commonest infections. Staphylococcus aureus was the commonest organism in the former, while gram negative organisms, Escherichia coli and Klebsiella species, were predominant in the latter. Pathogens similar to those found from patients were cultured from random samples taken from the floor, beds, towels, sinks and antiseptic containers in the wards. Sensitivity patterns of isolated pathogens to antimicrobial agents showed that S. aureus was highly sensitive to cloxacillin, erythromycin, and gentamicin, while the gram negative organisms were highly sensitive to gentamicin. Our study shows that the problem of nosocomial infection in paediatric wards requires urgent attention. There is a need to institute preventive measures including provision of proper nursing care, maintenance of sterile environment, and reduction of duration of hospital stay.
authors.affiliation: Department of Paediatrics and Child Health, Faculty of Medicine, University of Dar es Salaam, Tanzania.
authors.forename: H
authors.initials: H
authors.lastname: Isaack
authors.forename: R L
authors.initials: RL
authors.lastname: Mbise
authors.forename: K F
authors.initials: KF
authors.lastname: Hirji
mesh_terms: D000046:Academic Medical Centers; D001424:Bacterial Infections / Q000453:epidemiology* / Q000209:etiology / Q000382:microbiology; D015362:Child Nutrition Disorders / Q000145:classification / Q000150:complications*; D002675:Child, Preschool; D003428:Cross Infection / Q000453:epidemiology* / Q000209:etiology / Q000382:microbiology; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D009752:Nutritional Status; D011502:Protein-Energy Malnutrition / Q000145:classification / Q000150:complications*; D013636:Tanzania / Q000453:epidemiology