The clinical identification and quantification of photodamage.
The distinction between intrinsic and extrinsic ageing can be made on both histological and clinical grounds. Clinical criteria associated with the diagnosis of extrinsic ageing are coarse wrinkles, actinic lentigines, elastotic conditions, purpura, telangiectasia and cutaneous neoplasms. These parameters are always superimposed on changes associated with intrinsic ageing: namely, fine wrinkles and benign growths. There is heightened interest in extrinsic ageing as a result of studies demonstrating the efficacy of topical tretinoin in improving this condition. As a consequence, systems for grading extrinsic ageing have been developed, including a photographic standard scale which removes some of the subjectivity inherent to current methodology.
Griffiths
C E
CE
Department of Dermatology, University of Michigan Medical Center, Ann Arbor 48109-0314.
D000328:Adult; D004548:Elasticity; D005260:Female; D006801:Humans; D007642:Keratosis / Q000473:pathology; D008297:Male; D008548:Melanosis / Q000473:pathology; D012867:Skin / Q000473:pathology / Q000528:radiation effects*; D015595:Skin Aging / Q000473:pathology* / Q000528:radiation effects; D012878:Skin Neoplasms / Q000473:pathology; D012880:Skin Pigmentation; D013472:Sunlight / Q000009:adverse effects*