Hemostatic profile in neonatal septicemia.
Hemostatic profile was studied in 25 full term non-asphyxiated neonates with blood culture-proven septicemia. Observations were compared with that of 25 healthy, non-asphyxiated, full term, birth weight and age-matched controls. Detailed coagulation tests & platelet studies were done in each of the 50 neonates by standard techniques. Hemostatic defects occurred in 96% of the septicemic neonates and none in the control group irrespective of the occurrence of clinical bleeding. The coagulation tests were deranged in 805 and platelet function tests in 92% of patients. These tests were significantly deranged in septicemic neonates as compared to control group.
Alamelu
V
V
Department of Pediatrics, Kalawati Saran Children's Hospital, New Delhi.
Dutta
A K
AK
Narayan
S
S
Saili
A
A
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D001777:Blood Coagulation; D001792:Blood Platelets / Q000502:physiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010314:Partial Thromboplastin Time; D010977:Platelet Factor 3 / Q000032:analysis; D010979:Platelet Function Tests; D013918:Thrombin Time
D000900:Anti-Bacterial Agents; D010977:Platelet Factor 3