title: A comparison of peroxidase and cytochrome P-450.
abstract: A peroxidase has 1-electron oxidation as its characteristic activity, while that of cytochrome P-450 is hydroxylation. Both catalytic cycles involve similar high valency states of iron. However, a peroxidase can only accept electrons at the haem edge, while the substrate for cytochrome P-450 is bound in a precise orientation before the active state is created.
authors.affiliation: Department of Biochemistry, University of Bristol, School of Medical Sciences, U.K.
authors.forename: P M
authors.initials: PM
authors.lastname: Wood
mesh_terms: D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D007700:Kinetics; D010084:Oxidation-Reduction; D010544:Peroxidases / Q000378:metabolism*; D010944:Plants / Q000201:enzymology*
chemical_list: D003577:Cytochrome P-450 Enzyme System; D010544:Peroxidases