title: Acute effects of high frequency vagal nerve stimulation on balance and cognitive motor performance in epilepsy: three case study reports.
abstract: Quantitative measures of area of sway, total sway, and cognitive function failed to show significant differences in acute (50 minute) "ON-OFF-ON-OFF" studies of high frequency left vagal stimulation in three epileptic patients undergoing treatment for chronic complex partial seizures. Fluctuation in blood levels of anticonvulsants may have been associated with some clinical effects. There were no significant adverse effects of acute left vagal stimulation in these three subjects.
authors.affiliation: McMaster University Medical Centre, Hamilton, Ontario, Canada.
authors.forename: B M
authors.initials: BM
authors.lastname: Clarke
authors.forename: A R
authors.initials: AR
authors.lastname: Upton
authors.forename: H M
authors.initials: HM
authors.lastname: Griffin
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D004599:Electric Stimulation Therapy / Q000295:instrumentation*; D017029:Epilepsy, Complex Partial / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D008297:Male; D004856:Postural Balance / Q000502:physiology*; D019736:Prostheses and Implants; D011597:Psychomotor Performance / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D014630:Vagus Nerve / Q000502:physiology*
chemical_list: D000927:Anticonvulsants