title: Autoreactive cytotoxic cells in rabbits after prolonged immunostimulation.
abstract: Rabbits immunized for 6 months with different amounts of sterile human serum showed weight loss and a decrease in leukocytes. The lymphocyte population reacting to ConA contained autoreactive cells capable of causing 51Cr release from labeled cells from a culture consisting of splenic and peripheral lymphocytic cells from the same animal.
authors.affiliation: Istituto di Microbiologia, I Facoltà di Medicina e Chirurgia, Università di Napoli, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Galdiero
authors.forename: C
authors.initials: C
authors.lastname: Romano Carratelli
authors.forename: I
authors.initials: I
authors.lastname: Nuzzo
authors.forename: C
authors.initials: C
authors.lastname: Bentivoglio
authors.forename: M P
authors.initials: MP
authors.lastname: Galdiero
mesh_terms: D000818:Animals; D006801:Humans; D007114:Immunization; D007273:Injections, Intramuscular; D007958:Leukocyte Count; D008213:Lymphocyte Activation; D007959:Lymphocyte Culture Test, Mixed; D011817:Rabbits / Q000276:immunology*; D013045:Species Specificity; D013154:Spleen / Q000276:immunology / Q000473:pathology; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*