title: Olfactory receptor neurons from antennae of developing male Manduca sexta respond to components of the species-specific sex pheromone in vitro.
abstract: Male-specific olfactory receptor neurons, dissociated from developing antennae of the moth Manduca sexta and grown in long-term primary cell culture, can respond to at least one component of the female moth's sex-pheromone blend with the opening of a nonspecific cation channel. This response does not require the coapplication of pheromone-binding protein.
authors.affiliation: Arizona Research Laboratories, Division of Neurobiology, University of Arizona, Tucson 85721.
authors.forename: M
authors.initials: M
authors.lastname: Stengl
authors.forename: F
authors.initials: F
authors.lastname: Zufall
authors.forename: H
authors.initials: H
authors.lastname: Hatt
authors.forename: J G
authors.initials: JG
authors.lastname: Hildebrand
mesh_terms: D015761:4-Aminopyridine / Q000494:pharmacology; D015124:8-Bromo Cyclic Adenosine Monophosphate / Q000494:pharmacology; D000584:Amiloride / Q000494:pharmacology; D000818:Animals; D002121:Calcium Channel Blockers / Q000494:pharmacology; D002412:Cations; D002478:Cells, Cultured; D006152:Cyclic GMP / Q000031:analogs & derivatives / Q000494:pharmacology; D004553:Electric Conductivity / Q000187:drug effects; D007473:Ion Channels / Q000187:drug effects / Q000502:physiology; D008564:Membrane Potentials / Q000187:drug effects; D009036:Moths / Q000502:physiology*; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D010675:Pheromones / Q000494:pharmacology*; D011189:Potassium Chloride / Q000494:pharmacology; D011984:Sensory Receptor Cells / Q000187:drug effects / Q000502:physiology*; D013779:Tetrodotoxin / Q000494:pharmacology
chemical_list: D002121:Calcium Channel Blockers; D002412:Cations; D007473:Ion Channels; D010675:Pheromones; D015124:8-Bromo Cyclic Adenosine Monophosphate; C016276:8-bromocyclic GMP; D013779:Tetrodotoxin; D011189:Potassium Chloride; D000584:Amiloride; D015761:4-Aminopyridine; D006152:Cyclic GMP