title: An unusual coloured compound in digests of senile nuclear cataract lens proteins.
abstract: An unusual pink compound has been isolated from the proteolytic digests of senile nuclear cataract proteins by adsorption onto Sephadex G-10. The tiny amounts obtained precluded definitive structural elucidation, however TLC comparisons show that it resembles triphenodioxazine-1,8-dicarboxylic acid, a pink heterocyclic chemical formed by oxidative condensation of 3-hydroxyanthranilic acid.
authors.affiliation: Australian Cataract Research Foundation, University of Wollongong, N.S.W.
authors.forename: R J
authors.initials: RJ
authors.lastname: Truscott
authors.forename: E
authors.initials: E
authors.lastname: Langenberg
mesh_terms: D002386:Cataract / Q000378:metabolism*; D002850:Chromatography, Gel; D002855:Chromatography, Thin Layer; D003116:Color; D003459:Crystallins / Q000302:isolation & purification; D003911:Dextrans; D003998:Dicarboxylic Acids / Q000737:chemistry / Q000302:isolation & purification*; D005782:Gels; D006801:Humans; D007908:Lens, Crystalline / Q000737:chemistry*; D010078:Oxazines / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D003459:Crystallins; D003911:Dextrans; D003998:Dicarboxylic Acids; D005782:Gels; D010078:Oxazines; C075072:triphenodioxazine-1,8-dicarboxylic acid; C025614:sephadex