Comparison of pregnancy rates following gamete intrafallopian transfer (GIFT) under general anesthesia with thiopental sodium or propofol.
OBJECTIVE
To determine whether the pregnancy rate for gamete intrafallopian transfer (GIFT) patients who received thiopental sodium was different from the pregnancy rate for patients who received propofol for the induction of general anesthesia.


METHODS
Retrospective review of clinical records.


METHODS
Private outpatient infertility clinic.


METHODS
Two hundred eighty-two consecutive GIFT procedures performed on 230 patients with infertility.


METHODS
Patients undergoing GIFT were divided into two groups on the basis of whether they received thiopental or propofol for induction of anesthesia.


RESULTS
Clinical pregnancy following each GIFT procedure was assessed by multiple-serum beta human chorionic gonadotropin and ultrasound determinations. The pregnancy rates of 24.6% and 25.8% for the thiopental and propofol groups, respectively, were not significantly different.


CONCLUSIONS
The pregnancy rate following GIFT for patients given propofol for induction of general anesthesia did not differ from that for patients given thiopental.
Pierce
E T
ET
Department of Anaesthesia, Harvard Medical School, Boston, MA.
Smalky
M
M
Alper
M M
MM
Hunter
J A
JA
Amrhein
R L
RL
Pierce
E C
EC
D000328:Adult; D000771:Anesthesia, Intravenous; D006063:Chorionic Gonadotropin / Q000097:blood / Q000627:therapeutic use; D018997:Chorionic Gonadotropin, beta Subunit, Human; D005260:Female; D015181:Gamete Intrafallopian Transfer; D006801:Humans; D007247:Infertility, Female / Q000628:therapy; D016729:Leuprolide / Q000627:therapeutic use; D008596:Menotropins / Q000627:therapeutic use; D009865:Oocytes; D010446:Peptide Fragments / Q000097:blood; D011247:Pregnancy / Q000097:blood; D015742:Propofol / Q000008:administration & dosage; D012189:Retrospective Studies; D013874:Thiopental / Q000008:administration & dosage
D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D010446:Peptide Fragments; D008596:Menotropins; D016729:Leuprolide; D013874:Thiopental; D015742:Propofol