123I-methylene blue: an unsatisfactory parathyroid imaging agent.
This study was designed to examine the possible use of 123I-labelled methylene blue as a parathyroid imaging agent. Five patients were studied, all of whom had parathyroid adenomas which were successfully localized preoperatively with 201Tl and 99Tcm-sestamibi, and which were subsequently proven at surgery. The 123I-labelled methylene blue localized only one of these adenomas, was negative in two and had equivocal uptake in the remaining two patients. It is therefore concluded that compared to other radionuclide methods for localizing parathyroid adenomas this agent is unsatisfactory.
Blower
P J
PJ
Kent and Canterbury Hospital, UK.
Kettle
A G
AG
O'Doherty
M J
MJ
Collins
R E
RE
Coakley
A J
AJ
D000236:Adenoma / Q000000981:diagnostic imaging*; D006801:Humans; D007457:Iodine Radioisotopes; D008751:Methylene Blue; D015609:Organotechnetium Compounds; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D017256:Technetium Tc 99m Sestamibi; D013794:Thallium Radioisotopes
D007457:Iodine Radioisotopes; D015609:Organotechnetium Compounds; D013794:Thallium Radioisotopes; D017256:Technetium Tc 99m Sestamibi; D008751:Methylene Blue