title: Ovarian mucinous cystadenocarcinoma producing alpha-fetoprotein. A case report.
abstract: A 62-year-old woman with a complaint of abdominal distention underwent surgery to remove a tumor in her left ovary. The serum alpha-fetoprotein (AFP) level was 4,130 ng/ml. Histologically, the tumor was diagnosed as a mucinous cystadenocarcinoma with a small area of solid proliferation of tumor cells. The cells of the latter part were shown immunohistochemically to possess AFP. We suppose that a part of the mucinous cystadenocarcinoma dedifferentiates and produces AFP.
authors.affiliation: Department of Pathology, Jikei University School of Medicine, Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Nomura
authors.forename: Y
authors.initials: Y
authors.lastname: Miyasaka
authors.forename: M
authors.initials: M
authors.lastname: Murae
authors.forename: Y
authors.initials: Y
authors.lastname: Terashima
authors.forename: S
authors.initials: S
authors.lastname: Aizawa
mesh_terms: D001344:Autopsy; D003536:Cystadenocarcinoma / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008853:Microscopy; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000378:metabolism / Q000473:pathology*; D000509:alpha-Fetoproteins / Q000096:biosynthesis*
chemical_list: D000509:alpha-Fetoproteins