title: [Epilepsy and thyrotoxicosis in a 4-year-old boy].
abstract: Hyperthyroidism in childhood has a relative incidence of 5%. The presence of epilepsy secondary to thyrotoxicosis is very unusual. We report the case of a four-year old boy with thyrotoxicosis due to Graves' disease. This patient developed a generalized tonic-clonic seizure followed by left sided partial motor status epilepticus. The EEG was markedly abnormal. The EEG was normal after five months of the ablative therapy. At the present time the patient is seizure-free without any antiepileptic medication and receiving replacement therapy with thyroxin due to post-ablation hypothyroidism. We conclude that this is the first reported case with this association in our country. We discuss the possible pathophysiological mechanism involved in the development of seizures in this patient.
authors.affiliation: Servicio de Neurología, Hospital Universitario Dr. José E. González, U.A.N.L. Monterrey, N.L. México.
authors.forename: R
authors.initials: R
authors.lastname: Rangel-Guerra
authors.forename: H R
authors.initials: HR
authors.lastname: Martínez
authors.forename: P
authors.initials: P
authors.lastname: García Hernández
authors.forename: J
authors.initials: J
authors.lastname: Alberto Sagastegui-Rodríguez
authors.forename: J
authors.initials: J
authors.lastname: Zacarías Villarreal
authors.forename: J
authors.initials: J
authors.lastname: Antonio Infante Cantú
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D013956:Antithyroid Agents / Q000627:therapeutic use; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004830:Epilepsy, Tonic-Clonic / Q000188:drug therapy / Q000209:etiology*; D006111:Graves Disease / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male
chemical_list: D000927:Anticonvulsants; D013956:Antithyroid Agents; D007457:Iodine Radioisotopes