New medical-purpose absorbent materials based on polyacrylic acid and alpha-cyanoacrylates, their structure and properties.
Hydrophylic porous polymers (HPP) obtained by polymerization of the alpha-cyanoacrylates under contact with solution of the polymeric carboxylic acids has the degree of water absorption up to 50.000 percent. Disclosed are the data on the HPP porosity investigation, water absorptions HPP are not toxic, do not exhibit allergenic and irritative actions, admit introduction of the medicine into HPP. The HPP films and sheets were used in the course of the experiment for treatment of purulent wounds. Their high effectiveness expressed in reduction of the adhesion time by 1.5 to 2 times was established.
Akimova
A Y
AY
Chigir
A N
AN
Zherdev
Y V
YV
D000042:Absorption; D000180:Acrylic Resins / Q000737:chemistry* / Q000592:standards / Q000627:therapeutic use; D000818:Animals; D003487:Cyanoacrylates / Q000737:chemistry* / Q000592:standards / Q000627:therapeutic use; D004353:Drug Evaluation, Preclinical; D006801:Humans; D011109:Polymethacrylic Acids / Q000737:chemistry* / Q000592:standards; D016062:Porosity; D013492:Suppuration; D013696:Temperature; D013818:Thermogravimetry; D014945:Wound Healing / Q000187:drug effects; D014947:Wounds and Injuries / Q000188:drug therapy / Q000503:physiopathology
D000180:Acrylic Resins; D003487:Cyanoacrylates; D011109:Polymethacrylic Acids; C006903:carbopol 940