An unusual coloured compound in digests of senile nuclear cataract lens proteins.
An unusual pink compound has been isolated from the proteolytic digests of senile nuclear cataract proteins by adsorption onto Sephadex G-10. The tiny amounts obtained precluded definitive structural elucidation, however TLC comparisons show that it resembles triphenodioxazine-1,8-dicarboxylic acid, a pink heterocyclic chemical formed by oxidative condensation of 3-hydroxyanthranilic acid.
Truscott
R J
RJ
Australian Cataract Research Foundation, University of Wollongong, N.S.W.
Langenberg
E
E
D002386:Cataract / Q000378:metabolism*; D002850:Chromatography, Gel; D002855:Chromatography, Thin Layer; D003116:Color; D003459:Crystallins / Q000302:isolation & purification; D003911:Dextrans; D003998:Dicarboxylic Acids / Q000737:chemistry / Q000302:isolation & purification*; D005782:Gels; D006801:Humans; D007908:Lens, Crystalline / Q000737:chemistry*; D010078:Oxazines / Q000737:chemistry / Q000302:isolation & purification*
D003459:Crystallins; D003911:Dextrans; D003998:Dicarboxylic Acids; D005782:Gels; D010078:Oxazines; C075072:triphenodioxazine-1,8-dicarboxylic acid; C025614:sephadex