Synthesis, characterization, and antibacterial activity of transition metal complexes with 5-hydroxy-7,4'-dimethoxyflavone.
Complexes of CuII, NiII, CoII, ZnII, FeIII, CrIII, CdII, and MnII with the natural product 5-hydroxy-7,4'-dimethoxyflavone have been synthesized and the probable structures of these complexes have been proposed on the basis of elemental analyses, molecular weight determination, magnetic moments, and electronic and IR spectral data. The presence of coordinated and crystal water molecules was demonstrated by thermal studies. The antibacterial activity of the ligand and all the complexes has been determined on gram positive and gram negative bacteria.
Wang
S X
SX
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, People's Republic of China.
Zhang
F J
FJ
Feng
Q P
QP
Li
Y L
YL
D047310:Apigenin; D001419:Bacteria / Q000187:drug effects*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004926:Escherichia coli / Q000187:drug effects; D005419:Flavonoids / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D008670:Metals / Q000737:chemistry*; D011514:Proteus vulgaris / Q000187:drug effects; D013055:Spectrophotometry, Infrared; D013211:Staphylococcus aureus / Q000187:drug effects; D013816:Thermodynamics
D005419:Flavonoids; D008670:Metals; C044998:apigenin dimethylether; D047310:Apigenin