title: Cardiac function in obstructive sleep apnea patients following uvulopalatopharyngoplasty.
abstract: Obstructive sleep apnea syndrome (OSAS) is associated with severe cardiac arrhythmias and conduction abnormalities. Cor pulmonale and right-sided heart failure may ensue. Uvulopalatopharyngoplasty (UPPP) is one of several treatment modalities suggested for OSAS. Tracheotomy and CPAP treatment in adult OSAS patients and adenotonsillectomy in children with OSAS were shown to lead to improvement in some cardiac parameters. Cardiac function was prospectively evaluated in 19 OSAS patients before and after UPPP. No significant changes after surgery were noted on electrocardiographic studies. Improvement in global and regional function of both ventricles was seen in 91% of the patients. A trend toward significant elevation in left ventricular ejection fraction and a statistically significant increase in right ventricular ejection fraction were observed (45% +/- 9% to 50% +/- 7% [p = 0.007]). Our results support performance of UPPP in selected OSAS patients for relief of potentially life-threatening cardiac pathologies.
authors.affiliation: Departments of Otolaryngology-Head and Neck Surgery, Tel-Aviv University Medical School, Hasharon Hospital, Golda Medical Center.
authors.forename: Y
authors.initials: Y
authors.lastname: Zohar
authors.forename: Y P
authors.initials: YP
authors.lastname: Talmi
authors.forename: H
authors.initials: H
authors.lastname: Frenkel
authors.forename: Y
authors.initials: Y
authors.lastname: Finkelstein
authors.forename: C
authors.initials: C
authors.lastname: Rudnicki
authors.forename: M
authors.initials: M
authors.lastname: Fried
authors.forename: Y
authors.initials: Y
authors.lastname: Zahavi
mesh_terms: D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000503:physiopathology; D005117:Cardiac Complexes, Premature / Q000503:physiopathology; D004452:Echocardiography; D015716:Electrocardiography, Ambulatory; D006321:Heart / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology; D010160:Palate, Soft / Q000601:surgery*; D010614:Pharynx / Q000601:surgery*; D011446:Prospective Studies; D012891:Sleep Apnea Syndromes / Q000601:surgery*; D013318:Stroke Volume / Q000502:physiology; D014609:Uvula / Q000601:surgery*; D016278:Ventricular Function, Right / Q000502:physiology