title: Brain-stem auditory evoked potentials in adults with Down's syndrome.
abstract: Brain-stem auditory evoked potentials (BAEPs) were examined in 37 adult patients with Down's syndrome and in 37 age-matched normal subjects. All absolute and interpeak latencies except for the interpeak latency IV-V were shorter in patients than in normal subjects. The amplitude of wave V and the amplitude ratio V/I were smaller in patients than in normal subjects. Short latencies in patients were considered to be due to the smaller size of the brain-stem or to faster conduction velocity. The prolonged interpeak latency IV-V and the smaller wave V may indicate physiological dysfunctions between the upper pons and the lower midbrain.
authors.affiliation: Department of Internal Medicine, Saga Medical School, Japan.
authors.forename: R
authors.initials: R
authors.lastname: Kakigi
authors.forename: Y
authors.initials: Y
authors.lastname: Kuroda
mesh_terms: D000161:Acoustic Stimulation; D000293:Adolescent; D000328:Adult; D004314:Down Syndrome / Q000503:physiopathology*; D004569:Electroencephalography; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011930:Reaction Time / Q000502:physiology