A monoclonal antibody that recognizes a formalin-resistant epitope on the p 24 core protein of HIV-1.
A murine monoclonal antibody (called H-11) that binds to the p 24 core protein of HIV-1 was characterized by radioimmuno-precipitation, immunofluorescence, western blot assays, immunocytochemistry and immunohistochemistry. This antibody was found to be especially suited for demonstrating the presence of HIV-1 in formalin-fixed, paraffin-embedded tissues.
Kaluza
G
G
Institut für Med. Virologie, Justus-Liebig-Universität, Giessen, FRG.
Willems
W R
WR
Lohmeyer
J
J
Altmannsberger
M
M
Bohle
R M
RM
Lübke
S
S
D000096:Acetone; D000328:Adult; D000368:Aged; D000911:Antibodies, Monoclonal / Q000302:isolation & purification; D000918:Antibody Specificity / Q000276:immunology; D015153:Blotting, Western; D004351:Drug Resistance / Q000276:immunology; D000939:Epitopes / Q000032:analysis; D005404:Fixatives; D005455:Fluorescent Antibody Technique; D005557:Formaldehyde; D015488:HIV Antigens / Q000032:analysis*; D016655:HIV Core Protein p24 / Q000276:immunology*; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008297:Male; D015531:Radioimmunoprecipitation Assay
D000911:Antibodies, Monoclonal; D000939:Epitopes; D005404:Fixatives; D015488:HIV Antigens; D016655:HIV Core Protein p24; D000096:Acetone; D005557:Formaldehyde