[AIDS in children. Experience at the National Institute of Pediatrics].
We describe retrospectively the experience with 44 cases of AIDS from January 1987 to October 1991 at the Instituto Nacional de Pediatria, a tertiary care children hospital in Mexico City. All patients with 2 ELISA and a positive Western Blot test were included. Thirty three patients were infected perinatally (75%) and 11 through blood transfusion (25%). Fourty one patients belonged to the P2 classification of the Centers for Disease Control. Chronic diarrhea (77%), lymphadenopathy (75%), hepatomegaly/splenomegaly (70%) and oral candidiasis (61%) were the most common clinical findings. Twenty patients died (45.4%). No statistical relation were found between survival rate and the way of transmission and age at onset. Autopsy was performed in 14 patients and revealed a sharp decrease of lymphoid tissue at all levels with severe thymic atrophy.
Desinor-Mompoint
O I
OI
Servicio de Infectología, Instituto Nacional de Pediatría, México, D.F., México.
González-Saldaña
N
N
Palacios-Saucedo
G
G
Gutiérrez-Ortiz
B
B
de León-Bojorge
B
B
Vázquez-Rivera
M
M
D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006776:Hospitals, Pediatric; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008800:Mexico / Q000453:epidemiology; D012189:Retrospective Studies; D016019:Survival Analysis