title: Influence of chromium on some physiological variables of Anabaena doliolum: interaction with metabolic inhibitors.
abstract: The impact of 2,4-dinitrophenol and chlorophenyl dimethylurea on ATP content, carbon fixation, O2 evolution, nitrogenase activity and Cr uptake of Anabaena doliolum has been studied. 2,4-Dinitrophenol has been found to be more toxic than chlorophenyldimethylurea for all these processes. However, when Cr toxicity to above variables was assessed in their presence the interaction was less than additive. An initial (10-15 min) concentration-dependent rapid Cr uptake, followed by a slow one, indicates a biphasic uptake. A significant inhibition of Cr uptake in the presence of both these metabolic inhibitors suggests the involvement of metabolic processes in Cr uptake.
authors.affiliation: Laboratory of Algal Biology, Banaras Hindu University, Varanasi, India.
authors.forename: L C
authors.initials: LC
authors.lastname: Rai
authors.forename: S K
authors.initials: SK
authors.lastname: Dubey
authors.forename: N
authors.initials: N
authors.lastname: Mallick
mesh_terms: D019297:2,4-Dinitrophenol; D000255:Adenosine Triphosphate / Q000378:metabolism; D017033:Anabaena / Q000187:drug effects / Q000378:metabolism*; D001692:Biological Transport / Q000187:drug effects; D002857:Chromium / Q000378:metabolism* / Q000494:pharmacology*; D004140:Dinitrophenols / Q000494:pharmacology*; D004347:Drug Interactions; D007700:Kinetics; D008782:Methylurea Compounds / Q000494:pharmacology*; D009591:Nitrogenase / Q000378:metabolism; D010100:Oxygen / Q000378:metabolism
chemical_list: D004140:Dinitrophenols; D008782:Methylurea Compounds; D002857:Chromium; D000255:Adenosine Triphosphate; D009591:Nitrogenase; C100088:monuron; D019297:2,4-Dinitrophenol; D010100:Oxygen