Solid cell nests of the thyroid gland. Optic and immunohistochemical study at autopsies.
In order to establish the prevalence of solid cell nests (SCN) in adult thyroids, we studied 100 consecutive glands at necropsy. These were serially sectioned and stained with routine and immunoperoxidase techniques in order to detect calcitonin, carcinoembryonic antigen, thyroglobulin and keratin. SCN may be considered as normal thyroid gland components, and they share with C cells a common origin in the ultimobranchial body.
Pianzola
H M
HM
Cátedra de Patología A, Facultad de Ciencias Médicas, Universidad Nacional de La Plata, Argentina.
Ottino
A
A
Castelletto
R H
RH
D000328:Adult; D000368:Aged; D002116:Calcitonin / Q000032:analysis*; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D005260:Female; D006801:Humans; D007633:Keratins / Q000032:analysis; D008297:Male; D008875:Middle Aged; D013954:Thyroglobulin / Q000032:analysis; D013961:Thyroid Gland / Q000737:chemistry / Q000166:cytology*
D002272:Carcinoembryonic Antigen; D007633:Keratins; D002116:Calcitonin; D013954:Thyroglobulin