[A clinicopathological study of leukemic kidney].
A clinicopathological study of leukemic kidney was carried out by observing the changes of the kidney in 104 autopsied cases of leukemia. The main changes of the leukemic kidney were increase of renal weight, calcinosis of renal tubules, interstitial leukemic cell infiltration, intravascular stasis and renal bleeding. Calcinosis intravascular stasis, renal bleeding as well as hyperuricemia may lead to abnormal urinary findings. The presence and severity of interstitial infiltration have no obvious relation with the level of blood urea nitrogen, creatinine and muric acid as well as the abnormal change of the urine. However, the presence of intravascular stasis by leukemic cells are correlated with the disturbance of renal function.
Zhang
S F
SF
Department of Hematology, Shenyang Army General Hospital.
Wang
H L
HL
Guo
B Y
BY
D000293:Adolescent; D000328:Adult; D000368:Aged; D002114:Calcinosis / Q000473:pathology; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology*; D007684:Kidney Tubules / Q000473:pathology; D007948:Leukemia, Monocytic, Acute / Q000473:pathology; D007951:Leukemia, Myeloid / Q000473:pathology*; D015470:Leukemia, Myeloid, Acute / Q000473:pathology; D017254:Leukemic Infiltration; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000473:pathology