title: Primary adenosquamous and squamous cell carcinoma of the colon and rectum.
abstract: Three new cases of squamous cell and adenosquamous carcinoma of the rectum are reported, bringing the total number of cases in the English medical literature to 72. Each of the three patients presented with painless hematochezia. Therapy was by surgical resection followed by chemoradiation therapy in two patients. The incidence, presentation, diagnostic criteria and methods, tumor location, natural history, theory of etiology and management of this unusual tumor are discussed.
authors.affiliation: Department of Surgery, St. Louis University School of Medicine, Missouri.
authors.forename: T A
authors.initials: TA
authors.lastname: Schneider
authors.forename: D H
authors.initials: DH
authors.lastname: Birkett
authors.forename: A M
authors.initials: AM
authors.lastname: Vernava
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D008297:Male; D012004:Rectal Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000628:therapy