title: The stentless bioprosthesis: surgical challenges and implications for long-term durability.
abstract: An attempt is made to analyse the factors which are expected to influence clinical results following implantation of a stentless porcine bioprosthesis. Long experience with implantation of allograft aortic valves provides a meaningful basis for comparison with a glutaraldehyde-fixed device. Morphological differences between the two valves involve the aortic wall and muscle shelf, and differences in valve preparation include the strength and stiffness of the aorta and the extensibility of the valve leaflets. As a result of these differences, sizing of the porcine valve is expected to be more critical than the allograft valve and the porcine valve is also expected to be more obstructive. Methods for reducing the obstructive element include the use of a composite aortic valve, a porcine pulmonary valve, or a valve in which the aorta is glutaraldehyde-fixed under pressure while the leaflets are pressure-free. The techniques available for implantation, namely freehand insertion, total root replacement and mini-root replacement, are examined.
authors.affiliation: Cardiothoracic Surgical Unit, Green Lane Hospital, Auckland, New Zealand.
authors.forename: B G
authors.initials: BG
authors.lastname: Barratt-Boyes
authors.forename: G W
authors.initials: GW
authors.lastname: Christie
authors.forename: P J
authors.initials: PJ
authors.lastname: Raudkivi
mesh_terms: D001021:Aortic Valve / Q000502:physiology / Q000601:surgery*; D001705:Bioprosthesis / Q000145:classification / Q000592:standards*; D003198:Computer Simulation; D004452:Echocardiography; D005976:Glutaral / Q000627:therapeutic use; D006350:Heart Valve Prosthesis / Q000145:classification / Q000592:standards*; D006439:Hemodynamics; D006801:Humans; D011474:Prosthesis Design / Q000592:standards; D015607:Stents / Q000592:standards; D013314:Stress, Mechanical; D014021:Tissue Preservation / Q000379:methods / Q000592:standards
chemical_list: D005976:Glutaral