title: [Efficacy of the use of a stabilized alpha2-macroglobulin concentrate in experimental burns].
abstract: The effectiveness of the use of a stabilized composition of alpha 2-macroglobulin concentrate obtained from fraction III of plasma proteins according to Cohn in burn disease in the experiment on guinea pigs was studied. Under the influence of intraabdominal administration for 4 days of alpha 2-macroglobulin concentrate with a stabilizer, healing of the burn wounds, normalization of a state of the animals occurred 2 times more rapidly than in control ones, activity of acid proteinases restored by day 5 (in control--by day 14) due to increase in activity of proteolytic enzyme inhibitors.
authors.forename: P M
authors.initials: PM
authors.lastname: Perekhrestenko
authors.forename: V M
authors.initials: VM
authors.lastname: Lositskaia
authors.forename: K A
authors.initials: KA
authors.lastname: Lobunets
authors.forename: M S
authors.initials: MS
authors.lastname: Voloshina
authors.forename: V M
authors.initials: VM
authors.lastname: Sizov
authors.forename: S B
authors.initials: SB
authors.lastname: Iakovenko
authors.forename: V A
authors.initials: VA
authors.lastname: Mashchenko
authors.forename: V P
authors.initials: VP
authors.lastname: Evtukh
mesh_terms: D000818:Animals; D002056:Burns / Q000188:drug therapy*; D004195:Disease Models, Animal; D005260:Female; D006168:Guinea Pigs; D007274:Injections, Intraperitoneal; D008297:Male; D013997:Time Factors; D000511:alpha-Macroglobulins / Q000737:chemistry / Q000627:therapeutic use*
chemical_list: D000511:alpha-Macroglobulins