title: Evaluation of the incremental diagnostic value and impact on patient treatment of thallium scintigraphy.
abstract: The incremental diagnostic yield of exercise 201Tl scintigraphy with visual and quantitative analysis was determined in 191 patients with known or suspected coronary artery disease (CAD). The coronary arteriogram was used as the gold standard. After pre-test clinical and exercise electrocardiographic data were taken into consideration, scintigraphy was found to have additional diagnostic value both in the diagnosis of CAD and of multivessel disease, with quantitative analysis being superior to visual analysis. The impact of 201Tl scintigraphy on the patient's treatment--conservative treatment versus revascularization--was also evaluated. The impact was relatively low, as the decision for revascularization was based primarily on the angiographic result and the severity of the anginal pain. This result reflects only the decision making process used in our clinic and permits no conclusion to be made concerning the possible value of 201Tl scintigraphy in this type of medical decision making process.
authors.affiliation: Department of Diagnostic Radiology (Division of Nuclear Medicine), Academic Hospital, Leiden, The Netherlands.
authors.forename: W P
authors.initials: WP
authors.lastname: Oosterhuis
authors.forename: M G
authors.initials: MG
authors.lastname: Niemeyer
authors.forename: A F
authors.initials: AF
authors.lastname: Kuijper
authors.forename: A H
authors.initials: AH
authors.lastname: Zwinderman
authors.forename: A
authors.initials: A
authors.lastname: Breeman
authors.forename: C A
authors.initials: CA
authors.lastname: Ascoop
authors.forename: F J
authors.initials: FJ
authors.lastname: Verzijlbergen
authors.forename: E E
authors.initials: EE
authors.lastname: van der Wall
authors.forename: E K
authors.initials: EK
authors.lastname: Pauwels
mesh_terms: D017023:Coronary Angiography; D003327:Coronary Disease / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000453:epidemiology; D004562:Electrocardiography; D005069:Evaluation Studies as Topic; D005080:Exercise Test; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011237:Predictive Value of Tests; D011877:Radionuclide Imaging; D013794:Thallium Radioisotopes
chemical_list: D013794:Thallium Radioisotopes