Possible involvement of the accessory sex glands in the regulation of pituitary hormones.
A time-course alteration in the blood levels of gonadotrophin was evaluated in male rats aged 49 days after: (a) removal of the seminal vesicles, (b) bilateral orchidectomy, or (c) bilateral orchidectomy together with removal of the seminal vesicles. Age-matched sham-operated animals served as controls. Removal of the seminal vesicles resulted in elevation in the blood levels of LH, FSH and prolactin compared to controls. As expected, bilateral orchidectomy also resulted in the elevation of serum gonadotrophins. In the absence of both the seminal vesicles and the testes, LH and FSH levels were increased further compared to orchidectomy alone. Thus the present study suggests the presence of a feedback mechanism between the seminal vesicles and pituitary which is more pronounced in the absence of the testes.
Hurkadli
K S
KS
Institute for Research in Reproduction (ICMR), Parel, Bombay, India.
Kapasi
A A
AA
Kadam
M S
MS
Billimoria
F R
FR
Sheth
A R
AR
D000818:Animals; D005640:Follicle Stimulating Hormone / Q000097:blood; D006062:Gonadotropins / Q000097:blood*; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D009919:Orchiectomy; D011388:Prolactin / Q000097:blood; D051381:Rats; D012669:Seminal Vesicles / Q000502:physiology* / Q000601:surgery
D006062:Gonadotropins; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone