title: Limb perfusion. An objective measure of hemodynamic improvement after angioplasty.
abstract: Forty-four patients undergoing femoropopliteal angioplasty were studied by magnetic resonance blood flowmetry to determine quantitative limb perfusion. Baseline limb perfusion averaged 0.52 +/- 0.15 mL/min per 100 cc of tissue. Perfusion values for successful angioplasties rose within 72 hours to a mean of 1.40 +/- 0.31 mL/min per 100 cc of tissue. There were five early failures (less than 30 days), in which perfusion fell to 0.54 +/- 0.10 mL/min per 100 cc of tissue; at 6 months, 12 additional angioplasties had failed, with limb perfusion values of 0.68 +/- 0.16 mL/min per 100 cc of tissue. At 6 months, perfusion in four additional limbs had decreased to between 0.7 and 1.0 mL/min per 100 cc of tissue, with a mean change of 0.59 mL/min per 100 cc of tissue; duplex ultrasound imaging at these sites showed restenoses ranging from 50% to 75%. We conclude that lower-leg limb perfusion appears to be a reliable measure of hemodynamic improvement after femoropopliteal angioplasty and may provide an early indicator of impending failure.
authors.affiliation: Department of Surgery, William Beaumont Hospital, Royal Oak, MI 48073.
authors.forename: P J
authors.initials: PJ
authors.lastname: Bendick
authors.forename: J L
authors.initials: JL
authors.lastname: Price
authors.forename: J L
authors.initials: JL
authors.lastname: Glover
mesh_terms: D000368:Aged; D000800:Angioplasty, Balloon / Q000706:statistics & numerical data; D016342:Angioplasty, Laser / Q000706:statistics & numerical data; D005260:Female; D005263:Femoral Artery / Q000503:physiopathology; D005500:Follow-Up Studies; D006439:Hemodynamics; D006801:Humans; D007383:Intermittent Claudication / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D007511:Ischemia / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D007866:Leg / Q000098:blood supply* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011150:Popliteal Artery / Q000503:physiopathology; D012212:Rheology