[Investigations of the ototoxicity of dicortinef (ear drops)].
The authors investigated the ototoxic influence of Dicortinef in laboratory animals. Their examinations were performed on 15 guinea pigs (weighing 210-380 g.) after application of this medicine to the fenestra rotunda. The harmful effect of Dicortinef was expressed by the characteristic fall in the microphonic potential (PM) and potential of the acoustic nerve (AP).
Ziemski
Z
Z
Kliniki Otolaryngologicznej AM we Wrocławiu.
Bochnia
M
M
Rak
J
J
Dziewiszek
W
W
D000818:Animals; D003055:Cochlear Microphonic Potentials / Q000187:drug effects*; D004338:Drug Combinations; D005438:Fludrocortisone / Q000031:analogs & derivatives / Q000633:toxicity; D006096:Gramicidin / Q000633:toxicity; D006168:Guinea Pigs; D009355:Neomycin / Q000633:toxicity; D010400:Penicillin G / Q000633:toxicity; D012405:Round Window, Ear / Q000187:drug effects*; D000159:Vestibulocochlear Nerve / Q000503:physiopathology
D004338:Drug Combinations; C077260:dicortineff; D006096:Gramicidin; D009355:Neomycin; D010400:Penicillin G; D005438:Fludrocortisone