title: Cutaneous leiomyosarcoma.
abstract: A child's head-sized tumor on the upper back developed in a 43-year-old man. In spite of an extensive operation for the tumor, he died of multiple metastasis 15 months after the operation. Histologically, tumor cells proliferated throughout the dermal and subcutaneous regions, and a boxed-in appearance was noted with silver staining. Because electron microscopic observations strongly suggested a smooth muscle origin, we diagnosed this case as cutaneous and subcutaneous leiomyosarcoma.
authors.affiliation: Department of Dermatology, St. Marianna University School of Medicine, Kanagawa, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Ikari
authors.forename: I
authors.initials: I
authors.lastname: Tokuhashi
authors.forename: I
authors.initials: I
authors.lastname: Haramoto
authors.forename: M
authors.initials: M
authors.lastname: Morita
authors.forename: T
authors.initials: T
authors.lastname: Chiba
authors.forename: N
authors.initials: N
authors.lastname: Shimoda
authors.forename: M
authors.initials: M
authors.lastname: Mizoguchi
authors.forename: K
authors.initials: K
authors.lastname: Seki
authors.forename: M
authors.initials: M
authors.lastname: Tadokoro
authors.forename: K
authors.initials: K
authors.lastname: Ohya
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000209:etiology / Q000556:secondary; D006801:Humans; D007890:Leiomyosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery / Q000648:ultrastructure; D008113:Liver Neoplasms / Q000209:etiology / Q000556:secondary; D008175:Lung Neoplasms / Q000209:etiology / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008297:Male; D008854:Microscopy, Electron; D009364:Neoplasm Recurrence, Local / Q000209:etiology / Q000473:pathology*; D012834:Silver; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery / Q000648:ultrastructure; D012983:Soft Tissue Neoplasms / Q000209:etiology / Q000556:secondary; D013194:Staining and Labeling / Q000379:methods
chemical_list: D012834:Silver