[Nuclear morphometry and DNA cytometry in the grading of malignant tumors of the salivary gland].
Nuclear morphometry and DNA cytometry were performed in 6 normal salivary glands and 37 malignant tumors of the salivary gland. Multivariate discrimination analysis was used to grade the malignant salivary gland tumors. The discrimination rate was 100% for normal salivary gland, benign tumor, high malignant carcinoma and low malignant carcinoma. It was 66.7% for borderline malignancies. These results indicate that quantitative cytological analysis is effective and reproducible in the grading of salivary gland tumors. Stepwise multivariate regression analysis showed that there was a very complicated correlation between DNA content and nuclear morphometric parameters of salivary gland tumors.
Zhang
W Z
WZ
Sun Yat-sen University of Medical Sciences, Guangzhou, Guangdong.
D000230:Adenocarcinoma / Q000235:genetics / Q000473:pathology; D000235:Adenolymphoma / Q000235:genetics / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000235:genetics / Q000473:pathology; D002467:Cell Nucleus / Q000473:pathology*; D004273:DNA, Neoplasm / Q000032:analysis*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007620:Karyometry; D012044:Regression Analysis; D012468:Salivary Gland Neoplasms / Q000235:genetics / Q000473:pathology*
D004273:DNA, Neoplasm