[Visceral leishmaniasis. Diagnosis by western blotting].
Using Western blotting, antibodies directed against a 94 kiloDalton Leishmania antigen are detectable in the sera of patients with visceral leishmaniasis. The absence of these antibodies in the sera of patients with other leishmaniasis, protozoiases, helminthiases, and fungal or bacterial diseases, makes it a biological marker of visceral leishmaniasis, and gives this method its value in immunodiagnosis.
Rolland
L
L
INSERM U313, Faculté de Médecine Pitié-Salpêtrière, Paris.
Monjour
L
L
Danis
M
M
Gentilini
M
M
D000953:Antigens, Protozoan / Q000032:analysis*; D015153:Blotting, Western / Q000379:methods*; D014355:Chagas Disease / Q000097:blood / Q000175:diagnosis / Q000276:immunology; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D016773:Leishmaniasis, Cutaneous / Q000097:blood / Q000175:diagnosis / Q000276:immunology; D007898:Leishmaniasis, Visceral / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D014123:Toxoplasmosis / Q000097:blood / Q000175:diagnosis / Q000276:immunology; D014353:Trypanosomiasis, African / Q000097:blood / Q000175:diagnosis / Q000276:immunology
D000953:Antigens, Protozoan