title: 4-acetylaplykurodin B and aplykurodinone B, two ichthyotoxic degraded sterols from the Mediterranean mollusk Aplysia fasciata.
abstract: Two ichthyotoxic lactones, 4-acetylaplykurodin B [1] and aplykurodinone B [2], were isolated from the external parts of the body of the mollusk Aplysia fasciata. Their structures, determined by spectroscopic and chemical means, are closely related to aplykurodin B [3] previously isolated from Aplysia kurodai. The interconversion of delta- and gamma-lactones in the aplykurodin derivatives has been also investigated.
authors.affiliation: Istituto per la Chimica di Molecole di Interesse Biologico, C.N.R., Arco Felice, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Spinella
authors.forename: M
authors.initials: M
authors.lastname: Gavagnin
authors.forename: A
authors.initials: A
authors.lastname: Crispino
authors.forename: G
authors.initials: G
authors.lastname: Cimino
authors.forename: E
authors.initials: E
authors.lastname: Martinez
authors.forename: J
authors.initials: J
authors.lastname: Ortea
authors.forename: G
authors.initials: G
authors.lastname: Sodano
mesh_terms: D000818:Animals; D001048:Aplysia / Q000737:chemistry*; D007189:Indans / Q000737:chemistry* / Q000302:isolation & purification; D007783:Lactones / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D015394:Molecular Structure; D009904:Optical Rotation
chemical_list: D007189:Indans; D007783:Lactones; C077372:4-acetylaplykurodin B; C077373:aplykurodinone B