title: Granulocyte colony stimulating factor in the management of chronic neutropenia.
abstract: OBJECTIVE
  To report two cases of chronic neutropenic states successfully treated with granulocyte colony stimulating factor (G-CSF).
  
  
  METHODS
  A 23-year-old man with severe congenital cyclic neutropenia causing lifelong recurrent infections and consequent debilitation presented with intractable infected leg ulcers. A 56-year-old man with acquired idiopathic neutropenia presented with severe perianal infection and sepsis.
  
  
  RESULTS
  Both patients were successfully treated with recombinant G-CSF.
  
  
  CONCLUSIONS
  G-CSF is an agent with major clinical potential for the therapy of primary neutropenic states.
authors.affiliation: Department of Haematology, Mater Misericordiae Hospitals, South Brisbane, QLD.
authors.forename: P V
authors.initials: PV
authors.lastname: Marlton
authors.forename: S J
authors.initials: SJ
authors.lastname: Wright
authors.forename: K M
authors.initials: KM
authors.lastname: Taylor
mesh_terms: D000328:Adult; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000151:congenital / Q000628:therapy*; D011994:Recombinant Proteins / Q000627:therapeutic use
chemical_list: D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor