title: Immunohistochemical study of the distribution of S-100 protein in pleomorphic adenomas of minor salivary glands.
abstract: Twelve pleomorphic adenomas of minor salivary gland origin were examined for the distribution of S-100 protein, detected using the peroxidase-antiperoxidase (PAP) method. Strong S-100 protein immunoreactivity was noted in areas containing plasmacytoid cells, stellate and spindle cells against a myxochondroid or hyalinous stroma, and solid epithelial areas. Tubular and duct-like structures showed variable stainability. Stromal tissue and normal salivary glands were generally negative for S-100 protein. These findings were compared with those reported elsewhere.
authors.affiliation: Department of Oral Pathology and Oral Medicine, University of Malaya, Kuala Lumpur, Malaysia.
authors.forename: C H
authors.initials: CH
authors.lastname: Siar
authors.forename: K H
authors.initials: KH
authors.lastname: Ng
mesh_terms: D008949:Adenoma, Pleomorphic / Q000737:chemistry / Q000473:pathology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D002467:Cell Nucleus / Q000737:chemistry / Q000648:ultrastructure; D002648:Child; D003238:Connective Tissue / Q000737:chemistry / Q000473:pathology; D003593:Cytoplasm / Q000737:chemistry / Q000648:ultrastructure; D004848:Epithelium / Q000737:chemistry / Q000473:pathology; D005260:Female; D006801:Humans; D006818:Hyalin; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D010950:Plasma Cells / Q000473:pathology; D009418:S100 Proteins / Q000032:analysis*; D012468:Salivary Gland Neoplasms / Q000737:chemistry / Q000473:pathology*; D012470:Salivary Glands, Minor / Q000737:chemistry / Q000473:pathology*
chemical_list: D009418:S100 Proteins