title: Synthesis and antibacterial activity of some imidazo[1,2-a]pyrimidine derivatives.
abstract: A series of 75 imidazo[1,2-a]pyrimidine derivatives were synthesized. The "in vitro" antibacterial activity of these compounds and their corresponding alpha-bromoketones against a variety of gram (+), gram (-) bacteria and Mycobacterium species is reported. Some of the prepared derivatives exhibited potent antimicrobial activity.
authors.affiliation: Laboratoire de Chimie Organique, Faculté de Pharmacie, Illkirch, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Rival
authors.forename: G
authors.initials: G
authors.lastname: Grassy
authors.forename: G
authors.initials: G
authors.lastname: Michel
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D007093:Imidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D007093:Imidazoles; D011743:Pyrimidines