[ATL and its virus].
A retrovirus called Human T cell leukemia virus type 1 (HTLV-1) is a causative agent of adult T cell leukemia (ATL). A cultured cell line called MT-2, produces constitutively HTLV-1. The characteristics of HTLV-1 produced from MT-2 has been extensively investigated. The molecular mechanism of ATL leukemogenesis by HTLV-1 is discussed.
Hatanaka
M
M
Department of Viral Oncology, Kyoto University, Japan.
D000595:Amino Acid Sequence; D001483:Base Sequence; D002478:Cells, Cultured; D005260:Female; D016356:Gene Products, tax; D016679:Genome, Viral; D015368:Human T-lymphotropic virus 1 / Q000235:genetics*; D006801:Humans; D015458:Leukemia, T-Cell / Q000378:metabolism / Q000382:microbiology*; D008969:Molecular Sequence Data; D011247:Pregnancy; D012367:RNA, Viral / Q000378:metabolism; D014771:Virion / Q000378:metabolism
D016356:Gene Products, tax; D012367:RNA, Viral