Thyroid function before and after induced abortion in normal pregnant women.
We assessed thyroid function before and after induced abortion in 25 normal pregnant women. Serum TSH was significantly increased (P less than 0.02), and serum hCG-beta was significantly reduced (P less than 0.001) 1 week after induced abortion, compared with the levels before induced abortion. There was a significant negative correlation between hCG-beta and TSH, and a positive one between hCG-beta and FT4 before induced abortion (P less than 0.02). No difference was observed in thyroid hormones before and 1 week after induced abortion. The results suggest that hCG stimulates the thyroid gland, gaining an advantage over TSH, in normal pregnant women.
Hara
H
H
3rd Department of Internal Medicine, Showa University School of Medicine, Tokyo, Japan.
Ban
Y
Y
Morita
Y
Y
Sato
R
R
D000028:Abortion, Induced; D000328:Adult; D006063:Chorionic Gonadotropin / Q000097:blood; D018997:Chorionic Gonadotropin, beta Subunit, Human; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D010446:Peptide Fragments / Q000097:blood; D011247:Pregnancy / Q000502:physiology*; D012016:Reference Values; D013961:Thyroid Gland / Q000502:physiology*; D013963:Thyroid Hormones / Q000097:blood; D013972:Thyrotropin / Q000097:blood; D013997:Time Factors
D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D010446:Peptide Fragments; D013963:Thyroid Hormones; D013972:Thyrotropin; D006854:Hydrocortisone