Granular basal cell tumor in a Wistar rat.
A granular cell variant of a cutaneous basal cell tumor in a Wistar rat is described. The tumor resembles the variant as described in man and dogs. The granular basal cells contain cytoplasmic PAS positive granules, and immunostained positively with HMW cytokeratins. Ultrastructurally, the cytoplasmic granules were secondary lysosomes.
Courtney
C L
CL
Department of Pathology and Experimental Toxicology, Parke-Davis Pharmaceutical Research Division, Warner-Lambert Co., Ann Arbor, Michigan 48105.
Hawkins
K L
KL
Graziano
M J
MJ
D000818:Animals; D002280:Basal Cell Carcinoma / Q000473:pathology* / Q000648:ultrastructure; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D006651:Histocytochemistry; D007124:Immunoenzyme Techniques; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012878:Skin Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D013194:Staining and Labeling