[Experimental study of atherosclerosis and cholelithiasis with the same treatment. I. Effects of yiqi huoxue and shugan liqi agents in atherosclerosis of rabbit].
This paper reports the treatment with Yiqi Huoxue and Shugan Liqi agents in atherosclerosis of rabbit. The results suggested: 1. Both decoctions could reduce the cholesterol of hypercholesterolemia and improve the atherosclerosis, but the former was better than the latter. 2. Both decoctions could alter the components of bile lipids, but on the contrary, the latter was better than the former in reducing the formation of gallstones. 3. Both decoctions could decrease the plasma concentration of LPO and ratio of TXB2/6-K-PGF1 alpha, while increase the ratio of cAMP/cGMP in plasma. So, the different prescriptions of TCM affecting the same link of pathogenesis might play the role of "Different Treatments in Same Disease".
Zhou
Q
Q
Dept of Pathophysiology, Liaoning Institute of TCM, Shenyang.
D015121:6-Ketoprostaglandin F1 alpha / Q000097:blood; D000818:Animals; D001161:Arteriosclerosis / Q000188:drug therapy*; D002769:Cholelithiasis / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D008054:Lipid Peroxides / Q000097:blood; D011817:Rabbits; D013929:Thromboxane B2 / Q000097:blood
D004365:Drugs, Chinese Herbal; D008054:Lipid Peroxides; D013929:Thromboxane B2; D015121:6-Ketoprostaglandin F1 alpha