[A patient with epilepsy presenting developmental regression after seizures--consideration of the mechanism from the findings of CT-scan and SPECT].
We report a 6-month-old female infant with frequent brief seizures who subsequently showed developmental regression. CT-scans right after her seizures revealed enlargement of bilateral subdural space more on the right side with an evidence to suggest destruction of the blood brain barrier in enhanced CT-scan, CT-scan, one month after the onset, showed diffuse brain atrophy. 123I-SPECT, which was performed 11 days after cessation of her seizures, still showed diffuse hypoperfusion predominantly in the right temporal area, and it returned to normal 3 months after the onset. We discussed the mechanisms of developmental regression in this case from the neuroradiological findings.
Sugama
S
S
Department of Pediatrics, Tokyo Jikei University School of Medicine, Aoto Hospital, Japan.
Tomita
K
K
Okazaki
M
M
Eto
Y
Y
Ito
F
F
Maekawa
K
K
D002675:Child, Preschool; D002658:Developmental Disabilities / Q000209:etiology* / Q000523:psychology; D004827:Epilepsy / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D012043:Regression, Psychology; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed