Molecular cloning and characterization of genes encoding rat pancreatic cholecystokinin (CCK)-releasing peptide (monitor peptide) and pancreatic secretory trypsin inhibitor (PSTI).
The genes encoding a rat pancreatic cholecystokinin (CCK)-releasing peptide (monitor peptide) and its structurally related peptide, rat pancreatic secretory trypsin inhibitor (PSTI), have been isolated and sequenced. The two genes share extremely high sequence similarity in the 5' flanking regions, suggesting that these regions may be responsible for the characteristic coordinate expression of the two peptides.
Tsuzuki
S
S
Department of Food Science and Technology, Faculty of Agriculture, Kyoto University, Japan.
Miura
Y
Y
Fushiki
T
T
Oomori
T
T
Satoh
T
T
Natori
Y
Y
Sugimoto
E
E
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA; D005091:Exons; D006133:Growth Substances; D036341:Intercellular Signaling Peptides and Proteins; D007438:Introns; D008969:Molecular Sequence Data; D010179:Pancreas / Q000378:metabolism*; D010187:Pancreatic Hormones / Q000235:genetics*; D051381:Rats; D015183:Restriction Mapping; D014359:Trypsin Inhibitor, Kazal Pancreatic / Q000235:genetics*; D014361:Trypsin Inhibitors / Q000235:genetics*
D006133:Growth Substances; D036341:Intercellular Signaling Peptides and Proteins; D010187:Pancreatic Hormones; C504705:Spink1 protein, rat; D014361:Trypsin Inhibitors; D014359:Trypsin Inhibitor, Kazal Pancreatic; D004247:DNA