Transmembrane signalling in T cells.
Transmembrane signalling to activate T cells to proliferate and differentiate is a complex multistep process. It is the focus of much current interest, mostly because a selective and well-controlled inhibition of the process will allow regulation, or at least modulation, of the immune response. Here, Sándor Damjanovich and colleagues review the contributions of Hungarian scientists to the understanding of signalling in lymphocytes in particular, and cell activation in general.
Damjanovich
S
S
Dept of Biophysics, University Medical School of Debrecen, Hungary.
Szöllösi
J
J
Trón
L
L
D015703:Antigens, CD / Q000276:immunology; D000945:Antigens, Differentiation, T-Lymphocyte / Q000276:immunology; D000954:Antigens, Surface; D018801:CD2 Antigens; D002118:Calcium / Q000378:metabolism; D002462:Cell Membrane / Q000276:immunology*; D006649:Histocompatibility Antigens / Q000276:immunology; D006801:Humans; D007165:Immunosuppression Therapy; D007473:Ion Channels / Q000378:metabolism; D017493:Leukocyte Common Antigens; D008213:Lymphocyte Activation / Q000276:immunology; D008562:Membrane Glycoproteins; D010749:Phosphoprotein Phosphatases; D011971:Receptors, Immunologic / Q000276:immunology; D015398:Signal Transduction / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
D015703:Antigens, CD; D000945:Antigens, Differentiation, T-Lymphocyte; D000954:Antigens, Surface; D018801:CD2 Antigens; D006649:Histocompatibility Antigens; D007473:Ion Channels; D008562:Membrane Glycoproteins; D011971:Receptors, Immunologic; D010749:Phosphoprotein Phosphatases; D017493:Leukocyte Common Antigens; D002118:Calcium