title: [A case of tracho-bronchial aspergillosis complicated with acute myeloblastic leukemia].
abstract: A 59-year-old male was admitted to our hospital in Jan. 1991 with complaints of general malaise and palpitation. Laboratory findings on admission showed anemia, thrombocytopenia and leukopenia consisted of 2.0% myeloblasts with Auerbodies. The bone marrow study showed granuloid hyperplasia with 45.5% myeloblasts. The diagnosis of acute myeloblastic leukemia (M1) was made. After BHAC-AMP therapy, he obtained complete remission. However, he complained of fever and cough, and his chest X ray film showed a focal infiltrative shadow in the right upper lung field. Antibiotics for bacteria and fungus were administered and the abnormal shadow improved in a week. However, as he had hemosputum, the bronchoscopic examination was performed, and multiple ulcers covered by yellow-white tissue were revealed on the wall of the trachea and bilateral main bronchi. Biopsy specimens obtained by transbronchial biopsy showed bronchial aspergillosis. Though intravenous infusion and inhalation of amphotericin B were effective for aspergillosis, he had a relapse of the leukemia and died in autumn, 1991.
authors.affiliation: Department of Internal Medicine, Almeida Memorial Hospital.
authors.forename: Y
authors.initials: Y
authors.lastname: Saburi
authors.forename: T
authors.initials: T
authors.lastname: Tashiro
authors.forename: T
authors.initials: T
authors.lastname: Ishii
authors.forename: S
authors.initials: S
authors.lastname: Miyazaki
authors.forename: M
authors.initials: M
authors.lastname: Masuda
authors.forename: T
authors.initials: T
authors.lastname: Mieno
authors.forename: A
authors.initials: A
authors.lastname: Moriuchi
authors.forename: H
authors.initials: H
authors.lastname: Kikuchi
authors.forename: M
authors.initials: M
authors.lastname: Nasu
mesh_terms: D001228:Aspergillosis / Q000150:complications*; D001982:Bronchial Diseases / Q000150:complications*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008297:Male; D008875:Middle Aged; D014133:Tracheal Diseases / Q000150:complications*