Fetal amino acids in normal pregnancies and in pregnancies complicated by intrauterine growth retardation.
Plasma amino acid concentrations were measured in normal (AGA) and intrauterine growth retarded (IUGR) percutaneous umbilical blood sampling (PUBS) performed for prenatal diagnosis or at elective cesarean section. IUGR fetuses present significantly lower concentrations of most amino acids, with a significant reduction of the umbilical veno-arterial difference for total alpha-amino nitrogen. These findings are present early in growth retarded fetuses and may be potentially responsible for the growth retardation.
Cetin
I
I
Clinica Ostetrico-Ginecologica, Università di Milano, Italy.
Marconi
A M
AM
Corbetta
C
C
Lanfranchi
A
A
Baggiani
A M
AM
Battaglia
F C
FC
Pardi
G
G
D000596:Amino Acids / Q000097:blood*; D001800:Blood Specimen Collection / Q000379:methods; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D005317:Fetal Growth Retardation / Q000097:blood*; D006801:Humans; D011247:Pregnancy / Q000097:blood*; D011248:Pregnancy Complications / Q000097:blood*; D011296:Prenatal Diagnosis / Q000379:methods; D012016:Reference Values
D000596:Amino Acids