The role of oocyte donation in women who are unsuccessful with in-vitro fertilization treatment.
Oocyte donation improves the chances of becoming pregnant in some women who are unsuccessful with in-vitro fertilization (IVF) treatment. A total of 119 IVF cycles achieved a pregnancy rate per cycle of 2.5% whereas the same women, when treated with 45 cycles of oocyte donation, achieved a 24.5% pregnancy rate per cycle. To ascertain which women may be helped by oocyte donation, IVF data were analysed according to the outcome of oocyte donation. There was a difference in the number of previous natural conceptions and live births, and in the IVF fertilization rate. There was no difference in the age of the women and the numbers of oocytes collected per cycle of IVF. New criteria are therefore suggested for recommending oocyte donation to women who have previously failed to become pregnant with IVF treatment.
Burton
G
G
Lister Fertility and Endocrine Centre, London, UK.
Abdalla
H I
HI
Kirkland
A
A
Studd
J W
JW
D000328:Adult; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008875:Middle Aged; D009865:Oocytes; D011247:Pregnancy; D014019:Tissue Donors