[Role of specific brain peptide factors in the pathogenesis and compensation of neurologic disorders and their use in the treatment of nervous system diseases].
New concepts of the molecular mechanisms implicated in the pathogenesis and compensation of central motor disorders are presented. It has been shown experimentally that specific peptide, postural asymmetry, and inactivation factors, play the leading part in these processes. The detection of these specific factors in the cerebrospinal fluid (CSF) of patients and convalescents allowed one to work out and test clinically a new method of treatment (CSF therapy) of patients with central motor disorders of varying genesis. The results of the clinical observations of two patients' groups (with cerebrovascular brain lesions and multiple sclerosis) are provided.
Vartanian
G A
GA
Neuĭmina
M V
MV
Golovkin
V I
VI
Bisaga
G N
GN
D000328:Adult; D000818:Animals; D001930:Brain Injuries / Q000628:therapy; D002493:Central Nervous System Diseases / Q000209:etiology / Q000628:therapy*; D002555:Cerebrospinal Fluid / Q000737:chemistry / Q000502:physiology*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000628:therapy; D009479:Neuropeptides / Q000032:analysis / Q000502:physiology*
D009479:Neuropeptides