title: [Ultrastructural and morphometric analysis of the Paneth cell reaction to administration of cholera toxin].
abstract: Experiments were made on 40 immature guinea--pigs which were divided into two groups. 20 animals received intraduodenal injections of cholera toxin and 20 others were injected normal saline (groups I and II, respectively). Group I animals exhibited a rapid fall in one--cell secretion of XS recorded on hour 6-12 after the injection of cholera toxin. Inhibition of functional activity was associated with defected synthesis of granules in the cells of Paneth.
authors.forename: V A
authors.initials: VA
authors.lastname: Shakhlamov
authors.forename: T G
authors.initials: TG
authors.lastname: Solnyshkova
mesh_terms: D000367:Age Factors; D000818:Animals; D002772:Cholera Toxin / Q000008:administration & dosage / Q000633:toxicity*; D003594:Cytoplasmic Granules / Q000187:drug effects; D006168:Guinea Pigs; D007422:Intestines / Q000166:cytology* / Q000187:drug effects / Q000648:ultrastructure
chemical_list: D002772:Cholera Toxin