Osmotic swelling and membrane conductances in A6 cells.
Hyposmotic basolateral perturbations (-30 mosmol/kg) in cultured renal layers (A6) increased basolateral membrane conductance more than 2-fold within 10 min; the increase was partly due to upregulation of K+ conductance, but other conductive pathways were also activated. The raise in apical membrane amiloride-sensitive Na+ conductance was less pronounced; it appears to be due to secondary effects.
Granitzer
M
M
Département de Physiologie, Université Catholique de Louvain, Bruxelles, Belgium.
Bakos
P
P
Nagel
W
W
Crabbé
J
J
D000818:Animals; D002478:Cells, Cultured; D004847:Epithelial Cells; D004848:Epithelium / Q000502:physiology; D007668:Kidney / Q000166:cytology; D008564:Membrane Potentials; D008839:Microelectrodes; D009994:Osmolar Concentration; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D014982:Xenopus laevis
D012964:Sodium; D011188:Potassium