title: The effect of short-term fasting and a single meal on protein synthesis and oxygen consumption in cod, Gadus morhua.
abstract: Rates of protein synthesis and oxygen consumption (MO2) in cod were compared in both fasted and refed animals. During a 14-day fast both protein synthesis and respiration rates fell to stable values after 6 days. When a meal of whole sandeel at 6% body weight was fed to fish fasted for 6 days, protein synthesis and MO2 increased to a maximum at between 12 and 18 h after feeding. Peak MO2 was about twice the pre-feeding values, while whole animal protein synthesis increased four-fold. There were differences between tissues in the timing of maximum protein synthesis; the liver and stomach responded faster than the remainder of the body. Maximum protein synthesis rates in the liver and stomach occurred at 6 h after feeding, at which time their calculated contribution to total MO2 was 11%. Similar calculations suggested that the integrated increment in whole animal protein synthesis contributed between 23% and 44% of the post-prandial increase in MO2. It was concluded that protein synthesis is an important contributor to increased MO2 after feeding in cod.
authors.affiliation: Department of Zoology, University of Aberdeen, UK.
authors.forename: A R
authors.initials: AR
authors.lastname: Lyndon
authors.forename: D F
authors.initials: DF
authors.lastname: Houlihan
authors.forename: S J
authors.initials: SJ
authors.lastname: Hall
mesh_terms: D000818:Animals; D004435:Eating / Q000502:physiology; D005215:Fasting / Q000378:metabolism; D005399:Fishes / Q000378:metabolism*; D007700:Kinetics; D010101:Oxygen Consumption; D014176:Protein Biosynthesis; D012313:RNA / Q000378:metabolism; D014018:Tissue Distribution
chemical_list: D012313:RNA