Confidence interval estimation of interaction.
Relative excess risk due to interaction, the proportion of disease among those with both exposures that is attributable to their interaction, and the synergy index have been proposed as measures of interaction in epidemiologic studies. This paper presents the methodology for obtaining confidence interval estimates of these indices utilizing routinely available output from multiple logistic regression software.
Hosmer
D W
DW
School of Public Health, University of Massachusetts, Amherst 01003.
Lemeshow
S
S
D016001:Confidence Intervals; D003627:Data Interpretation, Statistical; D004812:Epidemiologic Methods; D006801:Humans; D012044:Regression Analysis