[The C antigen of Francisella tularensis].
A new envelope antigen C, specific for virulent strains of Francisella tularensis, was revealed by immunodiffusion analysis. In contrast to antigens A and P this antigen is common for Francisella and Brucella. C-antigenic lipid fraction was obtained by chloroform-ethanol (1:1) extraction of bacterial slime. This fraction contained carbohydrates (31.6%) without proteins and detected by TLC glycolipid, which proved glycolipid nature of C-antigen. Introduction of C-fraction or alive F. tularensis resulted in accumulation of C. precipitins in blood serum.
Sukhar'
V V
VV
Uraleva
V S
VS
D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis* / Q000276:immunology / Q000302:isolation & purification; D002002:Brucella / Q000276:immunology; D002855:Chromatography, Thin Layer; D000939:Epitopes / Q000032:analysis / Q000276:immunology; D005603:Francisella / Q000276:immunology; D005604:Francisella tularensis / Q000276:immunology* / Q000472:pathogenicity; D007114:Immunization; D005779:Immunodiffusion; D011817:Rabbits; D014774:Virulence / Q000276:immunology
D000942:Antigens, Bacterial; D000939:Epitopes