title: Rat palatal histology related to denture-like appliances.
abstract: Two designs of palatal denture-like appliance were fitted to rats. Tooth- and tissue-borne appliances caused changes in epithelial thickness and keratin thickness, but these varied with anatomical site and type of appliance. A single inoculation of Candida albicans at the time of insertion of the appliance failed to establish infection consistently. Debris accumulation under the appliances was a problem which will restrict long-term studies with this model.
authors.affiliation: Department of Prosthodontics, Glasgow Dental Hospital and School, Scotland.
authors.forename: K J
authors.initials: KJ
authors.lastname: Jennings
authors.forename: D G
authors.initials: DG
authors.lastname: MacDonald
mesh_terms: D000818:Animals; D001485:Basement Membrane / Q000473:pathology; D002176:Candida albicans / Q000502:physiology; D003741:Dental Deposits / Q000473:pathology; D003779:Denture Design; D003781:Denture Retention; D003778:Dentures; D004848:Epithelium / Q000382:microbiology / Q000473:pathology; D007633:Keratins; D008297:Male; D009061:Mouth Mucosa / Q000382:microbiology / Q000473:pathology*; D010159:Palate / Q000382:microbiology / Q000473:pathology*; D051381:Rats; D017208:Rats, Wistar; D013499:Surface Properties
chemical_list: D007633:Keratins