Liquid meal emptying in non-ulcer dyspepsia: a study in 22 Thai patients.
Twenty-four patients with non-ulcer dyspepsia (NUD) were recruited for gastric emptying study of liquid meal before and after 1 week's treatment with domperidone (80 mg in 19, 40 mg in 2, dropout 1 and excluded 2). Delayed gastric emptying was found in 8 of 22 (36.36%). Clinical improvement was found in 11 patients after treatment. Gastric emptying improvement was found in 3 patients (2 without clinical improvement). No correlation was found between the clinical and gastric emptying improvement. (Fisher exact test p greater than 0.25). Impaired liquid emptying is common in NUD and domperidone improved clinical symptoms in 50 per cent of NUD in this study.
Ovartlarnporn
B
B
Department of Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand.
Ratanalert
S
S
Keowkarnkar
W
W
D000328:Adult; D004294:Domperidone / Q000627:therapeutic use; D004415:Dyspepsia / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D005746:Gastric Emptying; D006801:Humans; D008297:Male; D011446:Prospective Studies
D004294:Domperidone