title: Endobronchial irradiation with 192Ir in the treatment of malignant endobronchial obstruction.
abstract: From Jan 1, 1983 to April 30, 1989, 32 patients underwent 38 endobronchial treatments with 192Ir, bronchoscopically inserted for treatment of endobronchial obstructions secondary to bronchogenic carcinoma. Thirty-four of the 38 treatments were far enough apart to allow separate response analysis. Thirty of the 34 patients were symptomatically improved or stable; 22 of 24 patients who could be evaluated roentgenographically showed improved or stable chest roentgenograms, and ten of 12 patients evaluated bronchoscopically demonstrated improved patency of bronchial lumen.
authors.affiliation: Radiation Oncology Department, Research Medical Center, Kansas City, Mo.
authors.forename: J C
authors.initials: JC
authors.lastname: Paradelo
authors.forename: M J
authors.initials: MJ
authors.lastname: Waxman
authors.forename: B J
authors.initials: BJ
authors.lastname: Throne
authors.forename: T A
authors.initials: TA
authors.lastname: Beller
authors.forename: W J
authors.initials: WJ
authors.lastname: Kopecky
mesh_terms: D001918:Brachytherapy / Q000009:adverse effects / Q000379:methods; D001980:Bronchi / Q000473:pathology; D001999:Bronchoscopy; D002283:Carcinoma, Bronchogenic / Q000473:pathology / Q000532:radiotherapy*; D003251:Constriction, Pathologic; D006801:Humans; D007496:Iridium Radioisotopes / Q000627:therapeutic use*; D008175:Lung Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D009364:Neoplasm Recurrence, Local / Q000532:radiotherapy
chemical_list: D007496:Iridium Radioisotopes