title: [The C antigen of Francisella tularensis].
abstract: A new envelope antigen C, specific for virulent strains of Francisella tularensis, was revealed by immunodiffusion analysis. In contrast to antigens A and P this antigen is common for Francisella and Brucella. C-antigenic lipid fraction was obtained by chloroform-ethanol (1:1) extraction of bacterial slime. This fraction contained carbohydrates (31.6%) without proteins and detected by TLC glycolipid, which proved glycolipid nature of C-antigen. Introduction of C-fraction or alive F. tularensis resulted in accumulation of C. precipitins in blood serum.
authors.forename: V V
authors.initials: VV
authors.lastname: Sukhar'
authors.forename: V S
authors.initials: VS
authors.lastname: Uraleva
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis* / Q000276:immunology / Q000302:isolation & purification; D002002:Brucella / Q000276:immunology; D002855:Chromatography, Thin Layer; D000939:Epitopes / Q000032:analysis / Q000276:immunology; D005603:Francisella / Q000276:immunology; D005604:Francisella tularensis / Q000276:immunology* / Q000472:pathogenicity; D007114:Immunization; D005779:Immunodiffusion; D011817:Rabbits; D014774:Virulence / Q000276:immunology
chemical_list: D000942:Antigens, Bacterial; D000939:Epitopes