title: Acute closed lock in a patient with lupus erythematosus: case review.
abstract: Collagen failure has been shown to result in synovitis, joint adhesions, and internal joint derangement. This case report illustrates the similarities between patients with systemic lupus erythematosus and an internally deranged temporomandibular joint and patients with internal derangement with no lupus erythematosus. If abnormalities in intra-articular collagen tissue lead to adhesion formation and restrict normal mobility during translatory movements, joint mechanics would be compromised. Arthritic changes, vasculitis, and synovitis of systemic lupus erythematosus appear to be contributory factors in this pathophysiologic process. Diagnostic and therapeutic arthroscopic surgery was performed. Acute and chronic signs of synovitis were observed during surgery, and tissue samples were obtained for histologic interpretation.
authors.affiliation: Saint Margaret Mercy Healthcare Centers, South Campus, Dyer, Indiana.
authors.forename: D M
authors.initials: DM
authors.lastname: Bade
authors.forename: J H
authors.initials: JH
authors.lastname: Lovasko
authors.forename: J
authors.initials: J
authors.lastname: Montana
authors.forename: F L
authors.initials: FL
authors.lastname: Waide
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D013585:Synovitis / Q000209:etiology; D013705:Temporomandibular Joint Disorders / Q000209:etiology* / Q000503:physiopathology; D000267:Tissue Adhesions / Q000209:etiology; D014313:Trismus / Q000209:etiology*