title: Magnetic resonance imaging follow-up in Creutzfeldt-Jakob disease.
abstract: The history of a 67-year-old woman with histologically proven Creutzfeldt-Jakob disease (CJD) is presented. Before typical clinical and neurophysiological signs of CJD developed, magnetic resonance imaging (MRI) showed slightly enhanced signal intensity of the caudate nuclei and putamina in T2-weighted and proton density images, corresponding to spongiform degeneration in neuropathological examination. Five weeks later characteristical progressive cortical atrophy was demonstrated by follow-up MRI.
authors.affiliation: Neurologische Universitätsklinik, Universität Heidelberg, Federal Republic of Germany.
authors.forename: J
authors.initials: J
authors.lastname: Röther
authors.forename: A
authors.initials: A
authors.lastname: Schwartz
authors.forename: M
authors.initials: M
authors.lastname: Härle
authors.forename: K U
authors.initials: KU
authors.lastname: Wentz
authors.forename: P
authors.initials: P
authors.lastname: Berlit
authors.forename: M
authors.initials: M
authors.lastname: Hennerici
mesh_terms: D000368:Aged; D001284:Atrophy; D002421:Caudate Nucleus / Q000473:pathology; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D011699:Putamen / Q000473:pathology