title: Stillborns, partially monosomic and partially trisomic, in the offspring of a boar carrying a translocation: rcp(14;15)(q29;q24).
abstract: Smaller liters and an increased rate of stillbirth were observed among the offspring of a boar carrying a reciprocal translocation, rcp(14;15)(q29;q24). The translocation appeared to be of de novo origin since, according to the owner, the sire and dam of the proband boar both produced normal-sized litters and no stillbirths. The increased rate of stillbirth among offspring of the proband was due to the production of zygotes partially monosomic for chromosome 14 (14q29-qter) and partially trisomic for chromosome 15 (15q24----qter). Three out of 4 such stillborn piglets had a cleft palate. One of the 4 also had a cardiac septal defect. Two partially monosomic and partially trisomic foetuses recovered at 95 days' pregnancy appeared patho-anatomically normal. The smaller litters were assumed to be due to an early wastage of embryos having other types of unbalanced karyotypes caused by the reciprocal translocation.
authors.affiliation: Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala.
authors.forename: I
authors.initials: I
authors.lastname: Gustavsson
authors.forename: L
authors.initials: L
authors.lastname: Jönsson
mesh_terms: D000818:Animals; D002872:Chromosome Deletion; D002883:Chromosomes, Human, Pair 14; D002884:Chromosomes, Human, Pair 15; D005260:Female; D005313:Fetal Death / Q000235:genetics*; D006801:Humans; D011247:Pregnancy; D013552:Swine; D014178:Translocation, Genetic / Q000235:genetics*; D014314:Trisomy