[Activity of selected proteinase inhibitors in patients with disorders of lipid metabolism].
The study was aimed at verification of previously found, in animals with experimentally induced atherosclerosis, the disturbances of serum proteinases inhibitors: alpha-2-antiplasmin, alpha-1-antitrypsin and alpha-2-macroglobulin. In humans with hypercholesterolemia the decrease of serum activity of alpha-2-antiplasmin was observed. In humans with hypercholesterolemia and increased serum concentration of triacylglycerols no significant changes in activity of alpha-1-antitrypsin and alpha-2-macroglobulin were found--in comparison with control subjects.
Kopieczna-Grzebieniak
E
E
Katedry i Zakładu Biochemii i Chemii Sl. AM, Katowicach.
Drózdz
M
M
Grabowska-Bochenek
R
R
Piekarski
M
M
D000328:Adult; D000368:Aged; D003124:Colorimetry / Q000379:methods; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood* / Q000201:enzymology; D015228:Hypertriglyceridemia / Q000097:blood* / Q000201:enzymology; D008297:Male; D008875:Middle Aged; D000515:alpha 1-Antitrypsin / Q000032:analysis*; D000979:alpha-2-Antiplasmin / Q000032:analysis* / Q000172:deficiency; D000511:alpha-Macroglobulins / Q000032:analysis*
D000515:alpha 1-Antitrypsin; D000979:alpha-2-Antiplasmin; D000511:alpha-Macroglobulins