Adrenocortical blastoma.
We report a previously undescribed virilizing malignant adrenocortical tumor in an 21-month-old infant with elevated serum alphafetoprotein. The tumor consists of a peculiar mixture of immature epithelial and mesenchymal elements as well as slit-like spaces partially lined by primitive epithelial cells. Focally, the tumor has features reminiscent of the normal embryologic development of the adrenal cortex. A panel of immunohistochemical stains revealed only vimentin reactivity. We propose the term "adrenocortical blastoma" for this unusual neoplasm.
Molberg
K
K
Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75235-9072.
Vuitch
F
F
Stewart
D
D
Albores-Saavedra
J
J
D000306:Adrenal Cortex Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D008297:Male