title: [The effect of smoking on the resistance index of the umbilical artery and the middle cerebral artery].
abstract: 23 healthy smokers with uneventful singleton pregnancies underwent Doppler-flow measurements of the foetal umbilical artery and middle cerebral artery before and ten minutes after smoking one cigarette. In both arteries the resistance indices (RI) did not change significantly. Maternal mean arterial blood pressure and heart rate increased significantly after the smoking of the cigarette. Neither the group with an RI increase of greater than or equal to 5% in the foetal umbilical artery (n = 7) nor the group with an increase of the RI in the foetal umbilical artery and, at the same time, a decrease of the RI in the arteria cerebri media (n = 5), showed a significant difference concerning maternal haemodynamic parameters and the number of cigarettes smoked before and during pregnancy. The results suggest, that the smoking of one cigarette in uneventful pregnancy does not produce acute haemodynamic effects in the foetus.
authors.affiliation: Frauenklinik und Poliklinik rechts der Isar, TU München.
authors.forename: R
authors.initials: R
authors.lastname: Agudelo
authors.forename: K T
authors.initials: KT
authors.lastname: Schneider
authors.forename: E A
authors.initials: EA
authors.lastname: Dumler
authors.forename: H
authors.initials: H
authors.lastname: Graeff
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology; D001921:Brain / Q000098:blood supply* / Q000196:embryology; D002536:Cerebral Arteries / Q000000981:diagnostic imaging / Q000196:embryology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange / Q000502:physiology*; D011247:Pregnancy; D012016:Reference Values; D012907:Smoking / Q000009:adverse effects* / Q000503:physiopathology; D016216:Ultrasonography, Prenatal / Q000295:instrumentation*; D014469:Umbilical Arteries / Q000000981:diagnostic imaging; D014655:Vascular Resistance / Q000502:physiology*