title: Effects of material properties of femoral hip components on bone remodeling.
abstract: Bone loss around femoral hip stems is one of the problems threatening the long-term fixation of uncemented stems. Many believe that this phenomenon is caused by reduced stresses in the bone (stress shielding). In the present study the mechanical consequences of different femoral stem materials were investigated using adaptive bone remodeling theory in combination with the finite element method. Bone-remodeling in the femur around the implant and interface stresses between bone and implant were investigated for fully bonded femoral stems. Cemented stems (cobalt-chrome or titanium alloy) caused less bone resorption and lower interface stresses than uncemented stems made from the same materials. The range of the bone resorption predicted in the simulation models was from 23% in the proximal medial cortex surrounding the cemented titanium alloy stem to 76% in the proximal medial cortex around the uncemented cobalt-chrome stem. Very little bone resorption was predicted around a flexible, uncemented "iso-elastic" stem, but the proximal interface stresses increased drastically relative to the stiffer uncemented stems composed of cobalt-chrome or titanium alloy. However, the proximal interface stress peak was reduced and shifted during the adaptive remodeling process. The latter was found particularly in the stiffer uncemented cobalt-chrome-molybdenum implant and less for the flexible iso-elastic implant.
authors.affiliation: Biomechanics Section, University of Nijmegen, The Netherlands.
authors.forename: H
authors.initials: H
authors.lastname: Weinans
authors.forename: R
authors.initials: R
authors.lastname: Huiskes
authors.forename: H J
authors.initials: HJ
authors.lastname: Grootenboer
mesh_terms: D000497:Alloys; D001696:Biomechanical Phenomena; D015519:Bone Density; D016723:Bone Remodeling; D001862:Bone Resorption; D002858:Chromium Alloys; D003035:Cobalt; D003198:Computer Simulation; D004548:Elasticity; D005269:Femur / Q000503:physiopathology; D006622:Hip Prosthesis; D006801:Humans; D008954:Models, Biological; D013314:Stress, Mechanical; D014025:Titanium; D016474:Weight-Bearing
chemical_list: D000497:Alloys; D002858:Chromium Alloys; D003035:Cobalt; D014025:Titanium