title: [A case of SSPE presenting visual disturbance and serial MRI study].
abstract: A case of subacute sclerosing panencephalitis (SSPE) was reported. The patient was a 16-year-old boy and he initially developed visual disturbance. His neurologic symptoms were myoclonus, dementia, and visual disturbance which was rare as an initial symptom in SSPE. Fundoscopy revealed bilateral pole chorioretinitis and macular degeneration. Serial MRI study demonstrated the lesions in the brain and right eye ball. The distribution varied as time went on. T2-weighted MR images showed the lesions more clearly than T1-weighted MR images. In this case dementia was marked but the lesions in the cerebrum on the MR images were considerably smaller than expected. Although MR image is useful to show the lesions, the discrepancy between clinical signs and MR images may be present in the early stage in SSPE.
authors.affiliation: Division of Neurology, Himeji Central Hospital.
authors.forename: S
authors.initials: S
authors.lastname: Higashi
authors.forename: Y
authors.initials: Y
authors.lastname: Higashi
authors.forename: S
authors.initials: S
authors.lastname: Kuroda
authors.forename: I
authors.initials: I
authors.lastname: Kohira
authors.forename: A
authors.initials: A
authors.lastname: Kanzaki
mesh_terms: D000293:Adolescent; D002825:Chorioretinitis / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013344:Subacute Sclerosing Panencephalitis / Q000150:complications / Q000175:diagnosis*; D014786:Vision Disorders / Q000209:etiology*