Motors for fast axonal transport.
In neurons and other animal cells, membrane-bound vesicles course rapidly along cytoskeletal filaments to reach their destinations. Based on a variety of in vivo studies it is becoming clear that the microtubule-based motor, kinesin (and its relatives), drive vesicle movements in axons. Surprisingly, some axonal membranes have the capacity to move on both microtubules and actin filaments.
Schroer
T A
TA
Department of Biology, Johns Hopkins University, Baltimore, Maryland 21218.
D000818:Animals; D001370:Axonal Transport / Q000502:physiology*; D004398:Dyneins / Q000378:metabolism; D006801:Humans; D016547:Kinesins / Q000378:metabolism; D008870:Microtubules / Q000378:metabolism
D004398:Dyneins; D016547:Kinesins