title: Enterotoxigenic and necrotizing Escherichia coli in human diarrhoea in Spain.
abstract: Enterotoxigenic Escherichia coli (ETEC) strains of serotype 0153: K-:H45 CFA/I+ STa+ were associated with two outbreaks of neonatal diarrhoea that occurred in two different hospitals of Madrid, in one of which several children died. Two other outbreaks were associated with ETEC strains of serotypes 0159: K-:H21 (LT+) and 0159: K-:H4 (LT+ STa+) without CFA/I and CFA/II colonization factors. Necrotizing E. coli (NTEC) strains of serotype 06:K13, producing the cytotoxic necrotizing factor CNF1 and alpha-haemolysin, were also associated with two outbreaks of neonatal diarrhoea that occurred in a hospital in Madrid and in a hospital in Talavera de la Reina. The results of the characterization of some ETEC and NTEC strains isolated from sporadic cases of diarrhoea are also discussed.
authors.affiliation: Departamento de Microbiología y Parasitología, Facultad de Veterinaria, Universidad de Santiago, Lugo, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Blanco
authors.forename: E A
authors.initials: EA
authors.lastname: González
authors.forename: P
authors.initials: P
authors.lastname: Espinosa
authors.forename: M
authors.initials: M
authors.lastname: Blanco
authors.forename: J I
authors.initials: JI
authors.lastname: Garabal
authors.forename: M P
authors.initials: MP
authors.lastname: Alonso
mesh_terms: D000328:Adult; D001427:Bacterial Toxins / Q000032:analysis*; D002675:Child, Preschool; D003428:Cross Infection / Q000453:epidemiology / Q000382:microbiology*; D003967:Diarrhea / Q000453:epidemiology / Q000382:microbiology*; D003968:Diarrhea, Infantile / Q000453:epidemiology / Q000382:microbiology*; D004196:Disease Outbreaks; D004768:Enterotoxins / Q000032:analysis*; D004926:Escherichia coli / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000382:microbiology*; D029968:Escherichia coli Proteins; D005243:Feces / Q000382:microbiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D013030:Spain / Q000453:epidemiology
chemical_list: D001427:Bacterial Toxins; D004768:Enterotoxins; D029968:Escherichia coli Proteins; C034151:heat stable toxin (E coli); C027538:heat-labile enterotoxin, E coli