title: Methods for chromatographic determination of amanitins and related toxins in biological samples.
abstract: Methods for the chromatographic determination of amanitins, toxins of Amanita phalloides (Fr.), Link mushrooms and related toxins are reviewed; particular emphasis is given to high-performance liquid chromatographic methods. The main chemical and toxicological aspects are discussed, but the focus of the present review is on the analytical problems arising in a laboratory charged with the setting up of a procedure which can direct the appropriate clinical management of an intoxicated patient or solve a forensic case.
authors.affiliation: Clinical Chemistry Laboratory, Hospital of Legnago, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Dorizzi
authors.forename: D
authors.initials: D
authors.lastname: Michelot
authors.forename: F
authors.initials: F
authors.lastname: Tagliaro
authors.forename: S
authors.initials: S
authors.lastname: Ghielmi
mesh_terms: D000545:Amanita / Q000737:chemistry; D000546:Amanitins / Q000032:analysis* / Q000633:toxicity; D002845:Chromatography / Q000379:methods*; D006801:Humans; D009183:Mycotoxins / Q000032:analysis / Q000633:toxicity
chemical_list: D000546:Amanitins; D009183:Mycotoxins; C018358:phallotoxin; C018207:amatoxin