title: Optimum excitation of phases and amplitudes in a phased array hyperthermia system.
abstract: In order to achieve a desired temperature distribution inside and outside of malignant tissues, optimization techniques could be used in phased array hyperthermia systems to control effectively the amplitude and phase of the radiating elements. The optimization of a four-element phased array hyperthermia system operating at 432 MHz is examined theoretically. The proposed technique is based on a detailed physical model of the tissue medium to be heated in terms of both electromagnetic and thermal properties. A penalty function technique using a Newton method is applied to determine the optimum phases and amplitudes of the array. Several array geometries have been studied and numerical results are presented.
authors.affiliation: Department of Electrical Engineering, National Technical University of Athens, Greece.
authors.forename: K S
authors.initials: KS
authors.lastname: Nikita
authors.forename: N
authors.initials: N
authors.lastname: Maratos
authors.forename: N K
authors.initials: NK
authors.lastname: Uzunoglu
mesh_terms: D000465:Algorithms; D055592:Biophysical Phenomena; D001703:Biophysics; D001775:Blood Circulation / Q000502:physiology; D001831:Body Temperature; D004574:Electromagnetic Fields; D006801:Humans; D006979:Hyperthermia, Induced / Q000295:instrumentation / Q000379:methods*; D008954:Models, Biological; D008961:Models, Structural