A survey of lymphocyte chromosomal damage in Slovenian workers exposed to occupational clastogens.
Assays for sister-chromatid exchanges (SCE), unstable chromosome and chromatid aberrations and micronuclei were performed on blood lymphocytes from persons exposed protractedly to radiation or chemical hazards in the workplace. There was a general tendency with all endpoints examined for the yields to increase with years of working in the industry. This was especially marked for SCE. By comparison with a control group of administrative workers the levels of damage were higher, usually significantly so, in the occupational groups. These comprised workers at a nuclear research reactor, a hospital diagnostic X-ray department, a coal mine and a mercury ore mine.
al-Sabti
K
K
Jozef Stefan Institute, Ljubljana, Slovenia.
Lloyd
D C
DC
Edwards
A A
AA
Stegnar
P
P
D000328:Adult; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects / Q000473:pathology* / Q000528:radiation effects; D008297:Male; D008628:Mercury / Q000633:toxicity; D015162:Micronucleus Tests; D008875:Middle Aged; D009153:Mutagens / Q000633:toxicity*; D016273:Occupational Exposure; D012854:Sister Chromatid Exchange / Q000187:drug effects / Q000528:radiation effects*; D012907:Smoking; D014965:X-Rays; D015022:Yugoslavia
D009153:Mutagens; D008628:Mercury