[Pathogenesis, therapy, prevention and prognosis in chronic viral hepatitis].
The paper deals with the pathogenesis, therapy, prophylaxis and prognosis of three chronic viral hepatitides type B, C and Delta. The immunologic and virological processes that play a role in the development of chronicity or progression, furthermore, factors influencing the therapeutic responses are discussed in details. Until now various antiviral and immunomodulatory agents were administered in chronic type B hepatitis, recently the most promising results were reported using recombinant interferons. The importance of the prevention, with special regard to the vaccination with HBsAg-vaccine is briefly summarized. The treatment and prophylaxis of chronic type C hepatitis is not resolved yet, interferon may be effective only a part of cases. The therapy of Delta virus related chronic hepatitis means a major problem as well.
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Pécsi Orvostudományi Egyetem, I. Belgyógyászati Klinika.
D006528:Carcinoma, Hepatocellular / Q000453:epidemiology; D006509:Hepatitis B / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology / Q000628:therapy; D006526:Hepatitis C / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology / Q000628:therapy; D003699:Hepatitis D / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology / Q000628:therapy; D006518:Hepatitis Viruses / Q000302:isolation & purification; D006521:Hepatitis, Chronic / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology / Q000628:therapy; D006525:Hepatitis, Viral, Human / Q000453:epidemiology / Q000276:immunology / Q000382:microbiology / Q000628:therapy; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D007114:Immunization; D007372:Interferons / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000453:epidemiology; D011379:Prognosis
D007372:Interferons