Cell-cell contact mechanisms.
Exciting new findings link characteristic properties of the inflammatory process previously not linked functionally. For example, it is now clear that oxygen radicals and leukocyte adhesion are intimately related in a carefully transduced and orchestrated series of events that culminates in release of granule contents, but not before the leukocyte has safely transversed the vessel wall. In addition to defining separate heterocellular contacts and homocellular aggregation we must now consider equilibrium events that allow associations among cell-cell partnerships involving different cell types.
Ryan
U S
US
Monsanto Corporate Research, Monsanto Company, St Louis, Missouri.
Worthington
R E
RE
D000818:Animals; D001327:Autoimmune Diseases / Q000473:pathology; D001792:Blood Platelets / Q000473:pathology; D002240:Carbohydrate Sequence; D015815:Cell Adhesion Molecules / Q000378:metabolism; D002449:Cell Aggregation; D002450:Cell Communication; D016207:Cytokines / Q000502:physiology; D004730:Endothelium, Vascular / Q000473:pathology; D007249:Inflammation / Q000473:pathology*; D008969:Molecular Sequence Data; D009000:Monocytes / Q000473:pathology; D009504:Neutrophils / Q000473:pathology; D019007:P-Selectin; D010980:Platelet Membrane Glycoproteins / Q000502:physiology; D011961:Receptors, Fc / Q000502:physiology; D015398:Signal Transduction
D015815:Cell Adhesion Molecules; D016207:Cytokines; D019007:P-Selectin; D010980:Platelet Membrane Glycoproteins; D011961:Receptors, Fc