title: [A lupus-vulgaris like atypical mycobacteriosis caused by Mycobacterium xenopi (lupus xenopi)].
abstract: A case of lupus-vulgaris-like infection caused by Mycobacterium xenopi in a 62-year-old immunocompetent female patient is presented. A large cutaneous infiltration was seen in the right periorbital region. Histological examination revealed a granulomatous reaction of epithelioid cells and giant cells. M. xenopi was isolated from biopsy material and tuberculosis could be excluded. Isoniazid was effective in healing the lesion within a year. Such infections are well known for other mycobacteria but to our knowledge had not yet been described for M. xenopi. The characteristics of human infections with M. xenopi are summarized in a review of the literature and criteria for the diagnosis of atypical cutaneous mycobacterioses are proposed.
authors.affiliation: Hautklinik, Städtischen Krankenhauses Hildesheim.
authors.forename: P
authors.initials: P
authors.lastname: Kiehl
authors.forename: U
authors.initials: U
authors.lastname: Eicher
authors.forename: F
authors.initials: F
authors.lastname: Vakilzadeh
mesh_terms: D001706:Biopsy; D003937:Diagnosis, Differential; D005148:Facial Dermatoses / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000008:administration & dosage; D008177:Lupus Vulgaris / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D009170:Nontuberculous Mycobacteria / Q000187:drug effects / Q000302:isolation & purification; D012867:Skin / Q000473:pathology
chemical_list: D007538:Isoniazid