A prospective study into the value of patch and intradermal tests in identifying topical corticosteroid allergy.
We have prospectively performed patch and intradermal tests on 105 consecutive patients, attending for patch testing, to determine the optimum method of screening for corticosteroid hypersensitivity. Patch tests with Pivalone and a corticosteroid series (all 1% in ethanol) detected all the patients with steroid sensitivity. However, intradermal tests were essential to exclude false positive reactions and detect all relevant steroid allergies in any individual patient.
Wilkinson
S M
SM
Dermatology Department, North Staffordshire Hospital Centre, Stoke-on-Trent, U.K.
Heagerty
A H
AH
English
J S
JS
D000287:Administration, Topical; D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D003875:Drug Eruptions / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D005938:Glucocorticoids; D006801:Humans; D007428:Intradermal Tests; D008297:Male; D008875:Middle Aged; D010328:Patch Tests; D011446:Prospective Studies
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids