title: Activation of the Na+/K+/Cl- cotransport system by reorganization of the actin filaments in Ehrlich ascites tumor cells.
abstract: Reorganization (disassembly) of the actin filaments in Ehrlich ascites tumor cells, either by hypotonic treatment in the presence of Ca2+ or by addition of cytochalasin B, results in activation of the Na+/K+/Cl- cotransport system. However, other regulatory processes, some of which may be dependent on an intact filament system, are responsible for the activation of the Na+/K+/Cl- cotransport system after cell shrinkage.
authors.affiliation: Technological Laboratory, Danish Ministry of Fisheries, Technical University, Lyngby.
authors.forename: F
authors.initials: F
authors.lastname: Jessen
authors.forename: E K
authors.initials: EK
authors.lastname: Hoffmann
mesh_terms: D000199:Actins / Q000502:physiology*; D000818:Animals; D001692:Biological Transport; D002034:Bumetanide / Q000494:pharmacology; D002286:Carcinoma, Ehrlich Tumor; D002352:Carrier Proteins / Q000378:metabolism*; D002712:Chlorides / Q000378:metabolism*; D003571:Cytochalasin B / Q000494:pharmacology; D011188:Potassium / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism*; D028021:Sodium-Potassium-Chloride Symporters; D014407:Tumor Cells, Cultured
chemical_list: D000199:Actins; D002352:Carrier Proteins; D002712:Chlorides; D028021:Sodium-Potassium-Chloride Symporters; D002034:Bumetanide; D003571:Cytochalasin B; D012964:Sodium; D011188:Potassium