title: Use of arterialized venous blood sampling during incremental exercise tests.
abstract: Close agreement between arterialized venous and arterial pH, PCO2, and lactate has previously been demonstrated during steady-state exercise. The purpose of the present study was to compare arterialized venous and arterial pH, PCO2, K+, lactate, pyruvate, and epinephrine during the constantly changing circumstances of an incremental exercise test. Eight normal subjects undertook an incremental exercise test (increasing by 20 W/min) to exhaustion on a cycle ergometer during which simultaneous arterial and arterialized venous samples were drawn over the last 20 s of each work load. Linear regression of arterialized venous on arterial values showed that r varied from 0.97 to 0.99 for the variables examined and, therefore, showed that accurate estimates of arterial values could be made from the arterialized venous results during incremental testing. For many purposes it could be assumed that arterialized venous values equaled arterial values without serious error.
authors.affiliation: Laboratory of Applied Physiology, United Medical School, St. Thomas's Hospital, London, United Kingdom.
authors.forename: P
authors.initials: P
authors.lastname: McLoughlin
authors.forename: P
authors.initials: P
authors.lastname: Popham
authors.forename: R A
authors.initials: RA
authors.lastname: Linton
authors.forename: R C
authors.initials: RC
authors.lastname: Bruce
authors.forename: D M
authors.initials: DM
authors.lastname: Band
mesh_terms: D000328:Adult; D001158:Arteries; D001800:Blood Specimen Collection / Q000379:methods*; D002245:Carbon Dioxide / Q000097:blood; D004837:Epinephrine / Q000097:blood; D005069:Evaluation Studies as Topic; D015444:Exercise / Q000502:physiology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D008297:Male; D011188:Potassium / Q000097:blood; D011773:Pyruvates / Q000097:blood; D019289:Pyruvic Acid; D014680:Veins
chemical_list: D007773:Lactates; D011773:Pyruvates; D002245:Carbon Dioxide; D019344:Lactic Acid; D019289:Pyruvic Acid; D011188:Potassium; D004837:Epinephrine