title: [Effects of concanavalin A on different variants of adhesive reactions of human neutrophils].
abstract: The influence of Con A on human neutrophils adhesion in interactions with sepharose 4B, C3b-sephadex G-25, DEAE-sephadex A-25, polymethylmethacrylate was studied. In concentrations 25 mg/ml and more Con A completely inhibited IgG-dependent adhesion but had no influence on other types of adhesion reactions. The effect was due to Con A interaction with neutrophils and could not be reproduced by Con A pretreatment of IgG-sepharose. Results are considered to be a manifestation of lectin-dependent modulation of cell receptors functions.
authors.forename: I V
authors.initials: IV
authors.lastname: Chebotar'
authors.forename: A N
authors.initials: AN
authors.lastname: Maianskiĭ
authors.forename: K Iu
authors.initials: KIu
authors.lastname: Solov'ev
authors.forename: I V
authors.initials: IV
authors.lastname: Chelyshev
mesh_terms: D003208:Concanavalin A / Q000494:pharmacology*; D003911:Dextrans; D005782:Gels; D006801:Humans; D007202:Indicators and Reagents; D037102:Lectins; D008768:Methylmethacrylates; D009504:Neutrophils / Q000187:drug effects* / Q000502:physiology; D011956:Receptors, Cell Surface / Q000502:physiology; D012685:Sepharose / Q000031:analogs & derivatives; D000267:Tissue Adhesions
chemical_list: D003911:Dextrans; D005782:Gels; D007202:Indicators and Reagents; D037102:Lectins; D008768:Methylmethacrylates; D011956:Receptors, Cell Surface; C036210:immunoglobulin G-sepharose; D003208:Concanavalin A; D012685:Sepharose; C025614:sephadex