Free-radical mechanisms involved in the formation of sequence-dependent bistranded DNA lesions by the antitumor antibiotics bleomycin, neocarzinostatin, and calicheamicin.
Dedon
P C
PC
Division of Toxicology, Massachusetts Institute of Technology, Cambridge 02139.
Goldberg
I H
IH
D000617:Aminoglycosides; D000818:Animals; D000900:Anti-Bacterial Agents / Q000633:toxicity*; D000903:Antibiotics, Antineoplastic / Q000633:toxicity*; D001761:Bleomycin / Q000633:toxicity*; D004249:DNA Damage; D053281:Enediynes; D005609:Free Radicals; D006801:Humans; D009353:Zinostatin / Q000633:toxicity*
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic; D053281:Enediynes; D005609:Free Radicals; C055955:calicheamicin gamma(1)I; D001761:Bleomycin; D009353:Zinostatin