Lidocaine in refractory status epilepticus: confirmation of efficacy with continuous EEG monitoring.
Lidocaine was efficacious in 2 patients with refractory status epilepticus (RSE) unresponsive to several antiepileptic drugs (AEDs), including high-dose barbiturates. We confirmed the efficacy of lidocaine with, for the first time in adults, continuous EEG monitoring. Lidocaine, when properly used, may be a treatment option in RSE.
De Giorgio
C M
CM
Department of Neurology, USC School of Medicine, Los Angeles 90033.
Altman
K
K
Hamilton-Byrd
E
E
Rabinowicz
A L
AL
D000328:Adult; D004569:Electroencephalography / Q000187:drug effects* / Q000379:methods; D006801:Humans; D008012:Lidocaine / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D008991:Monitoring, Physiologic; D010424:Pentobarbital / Q000627:therapeutic use; D013226:Status Epilepticus / Q000188:drug therapy* / Q000503:physiopathology
D008012:Lidocaine; D010424:Pentobarbital