Suppressor T cells: some answers but more questions.
Many properties of suppressor T cells and the antigen-binding factors derived from them have evaded molecular genetic definition. Here, Martin Dorf and colleagues discuss recent data in the context of a growing awareness of the molecules and principles involved.
Dorf
M E
ME
Department of Pathology, Harvard Medical School, Boston, MA 02115.
Kuchroo
V K
VK
Collins
M
M
D000818:Animals; D000938:Antigen-Presenting Cells / Q000276:immunology; D000949:Histocompatibility Antigens Class II / Q000235:genetics / Q000276:immunology; D007108:Immune Tolerance; D008213:Lymphocyte Activation; D051379:Mice; D008815:Mice, Inbred Strains / Q000276:immunology; D016693:Receptors, Antigen, T-Cell, alpha-beta / Q000276:immunology; D013491:Suppressor Factors, Immunologic / Q000276:immunology; D016176:T-Lymphocyte Subsets / Q000276:immunology; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*
D000949:Histocompatibility Antigens Class II; C043911:I-J-antigen; D016693:Receptors, Antigen, T-Cell, alpha-beta; D013491:Suppressor Factors, Immunologic