title: Computer-controlled flow simulator for MR flow studies.
abstract: A novel computer-controlled flow simulator for use in magnetic resonance (MR) flow experiments was evaluated. The accuracy in constant-flow mode was better than 1%. The accuracy in pulsatile-flow mode was found to be dependent on the interconnecting tubing. The short-term and long-term reproducibilities of pulsatile waveforms were less than or equal to 0.4 mL/sec (1 standard deviation). Increased response times due to the lengths of tubing required in MR flow experiments were surmounted by using a modified tubing configuration and precompensated waveforms. Piston reversal was found not to cause major difficulties in MR flow experiments.
authors.affiliation: Department of Medical Biophysics, University Hospital, University of Western Ontario, London, Canada.
authors.forename: R
authors.initials: R
authors.lastname: Frayne
authors.forename: D W
authors.initials: DW
authors.lastname: Holdsworth
authors.forename: L M
authors.initials: LM
authors.lastname: Gowman
authors.forename: D W
authors.initials: DW
authors.lastname: Rickey
authors.forename: M
authors.initials: M
authors.lastname: Drangova
authors.forename: A
authors.initials: A
authors.lastname: Fenster
authors.forename: B K
authors.initials: BK
authors.lastname: Rutt
mesh_terms: D001775:Blood Circulation / Q000502:physiology*; D001808:Blood Vessels / Q000033:anatomy & histology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008955:Models, Cardiovascular; D008961:Models, Structural; D012212:Rheology