Roll, roll, roll your leucocyte gently down the vein....
The rapid advances being made in unravelling the biochemistry and function of the three categories of adhesion molecule involved in leucocyte-endothelial-cell interactions, namely selectins, integrins and the Ig super-family molecules, were highlighted at a recent meeting. In this short report, Nancy Hogg describes these developments and the prospects for anti-adhesion molecule therapy in the clinic.
Hogg
N
N
Imperial Cancer Research Fund, London, UK.
D000818:Animals; D015815:Cell Adhesion Molecules / Q000502:physiology; D004730:Endothelium, Vascular / Q000502:physiology; D006801:Humans; D016023:Integrins / Q000502:physiology; D007962:Leukocytes / Q000502:physiology*; D019007:P-Selectin; D010980:Platelet Membrane Glycoproteins / Q000502:physiology
D015815:Cell Adhesion Molecules; D016023:Integrins; D019007:P-Selectin; D010980:Platelet Membrane Glycoproteins