title: Flunarizine is effective in prophylaxis of headache associated with scleroderma.
abstract: Migraine-like headaches may occasionally be seen in patients with scleroderma. The mechanism of these headaches is not well established but may be secondary to central "Raynaud's phenomenon". We report a patient with such headaches that responded dramatically to the centrally acting calcium channel blocker, flunarizine. We suggest that flunarizine should be considered in the management of patients with scleroderma and migraine-like headaches.
authors.affiliation: Dept. of Medicine (Div. of Neurology), Royal University Hospital, Saskatoon, Canada.
authors.forename: R
authors.initials: R
authors.lastname: Mazagri
authors.forename: A
authors.initials: A
authors.lastname: Shuaib
mesh_terms: D005260:Female; D005444:Flunarizine / Q000627:therapeutic use*; D006261:Headache / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000150:complications*
chemical_list: D005444:Flunarizine