In human nasal mucosa, interleukin-5 accumulates and degranulates eosinophils, as well as increases responsiveness to histamine.
Terada
N
N
Dept. of O.R.L., Akita University School of Medicine, Japan.
Konno
A
A
Shirotori
K
K
Togawa
K
K
D000328:Adult; D015550:Cell Degranulation; D004804:Eosinophils / Q000502:physiology*; D005260:Female; D006632:Histamine; D006801:Humans; D015848:Interleukin-5 / Q000235:genetics / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000276:immunology* / Q000378:metabolism; D009299:Nasal Provocation Tests; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger / Q000235:genetics; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology; D012852:Sinusitis / Q000276:immunology
D015848:Interleukin-5; D012333:RNA, Messenger; D006632:Histamine