title: A study of chromium in human cataractous lenses and whole blood of diabetics, senile, and normal population.
abstract: Chromium (Cr) is of known biological importance, necessary for the maintenance of normal glucose metabolism. There is a lower level of blood Cr concentrations in cases of diabetes. Diabetes carries a risk of cataract development, so the potential effects of Cr on the eye may need to be studied in more depth. The presence of this trace element in both normal and cataractous human lenses has to our knowledge not been investigated so far. The concentration of total Cr in 61 human lenses and 38 blood samples was determined by electrothermal atomic absorption spectrometry with Zeeman effect (EAASZ). Analysis of the levels of Cr in human lenses shows a significant difference between normal and diabetic populations, and an absence of difference between senile and diabetic populations.
authors.affiliation: Laboratoire de Toxicologie, Faculté de Pharmacie, Nantes, France.
authors.forename: A
authors.initials: A
authors.lastname: Pineau
authors.forename: O
authors.initials: O
authors.lastname: Guillard
authors.forename: J F
authors.initials: JF
authors.lastname: Risse
mesh_terms: D000368:Aged; D002386:Cataract / Q000097:blood* / Q000209:etiology; D002857:Chromium / Q000032:analysis* / Q000097:blood; D003704:Dementia / Q000097:blood* / Q000150:complications; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000097:blood*; D006801:Humans; D007908:Lens, Crystalline / Q000737:chemistry*; D008875:Middle Aged; D013054:Spectrophotometry, Atomic
chemical_list: D002857:Chromium