[Effects of chronic experimental stress and endogenous opioids on histophysiological parameters of the thyroid gland].
In adult rabbits stress was modelled by electrostimulation of the hypothalamus ventromedial nucleus (15-hour-long session during 30 days) and medulla's raphe big nucleus which is one of the central places of the opioid peptides synthesis was irritated. It is revealed, that under stress thyroid gland responds by serum T3 increase in comparison with control animals with statistically significant variability of the T4 profile. Chronicity of the emotional agitation involves destructive changes in the thyroid parenchyma the hurting effect of the negative emotional factor is expressed less during opioid peptides complex activation. It is suggested that there are its own stress-limiting mechanisms in thyroid gland.
Krasnoperov
R A
RA
Glumova
V A
VA
Riashchikov
S N
SN
Proshutina
N E
NE
D000818:Animals; D004558:Electric Stimulation; D004723:Endorphins / Q000502:physiology*; D011817:Rabbits; D013315:Stress, Psychological / Q000473:pathology / Q000503:physiopathology*; D013961:Thyroid Gland / Q000473:pathology / Q000503:physiopathology*; D013974:Thyroxine / Q000097:blood; D013997:Time Factors; D014284:Triiodothyronine / Q000097:blood
D004723:Endorphins; D014284:Triiodothyronine; D013974:Thyroxine