Sudden unexpected death due to Taxus poisoning. A report of five cases, with review of the literature.
The toxicity of yew (Taxus) has been known since antiquity. However, in the past 31 years, to our knowledge only six cases of Taxus poisoning have been reported in the literature. In the present paper we add five cases. From a forensic point of view, intoxication with Taxus has three important aspects: (i) the clinical presentation, which among other causes should suggest Taxus intoxication; (ii) the fact that the diagnosis may often be easily made by examination of the contents of stomach, duodenum and small bowel and (iii) the widespread availability in the near future of Taxol, an anti-neoplastic drug which is an alkaloid extracted from Taxus. The clinical and autopsy findings are summarized, the diagnostic aspects are discussed and the literature concerning Taxus is reviewed.
Van Ingen
G
G
National Forensic Pathology, Rijswijk, The Netherlands.
Visser
R
R
Peltenburg
H
H
Van Der Ark
A M
AM
Voortman
M
M
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D010939:Plant Poisoning / Q000473:pathology*; D013405:Suicide