title: Intrapartum asphyxia in term and post term infants.
abstract: Many attempts have been made to identify infants at risk of suffering asphyxial brain damage. In a retrospective review of records at the Rotunda Hospital over a five year period all infants who died or suffered seizures, presumed secondary to asphyxia, were compared with the general hospital population. Out of 28,655 deliveries reviewed, there were 13 deaths in infants at or after term associated with perinatal asphyxia, and 32 surviving infants had asphyxial seizures. Seizures were regarded as asphyxial in origin if they occurred in the first forty eight hours of life and were associated with other clinical evidence of asphyxia. The incidence of abnormal presentations, assisted breech deliveries, instrumental deliveries and emergency caesarean sections was all increased in the asphyxial categories compared to the control population. Referral to the fetal assessment unit was associated with a seizure rate of 0.16/1000 live births compared with a rate of 1.4/1000 in the remaining non referred hospital population. Nineteen percent of the infants who seized subsequently developed cerebral palsy. It would appear from our data that referral to the fetal assessment unit and the consequent assignment to "high risk" status is associated with low risk in terms of asphyxial outcome.
authors.affiliation: Rotunda Hospital Dublin.
authors.forename: A
authors.initials: A
authors.lastname: Halligan
authors.forename: M
authors.initials: M
authors.lastname: Connolly
authors.forename: T
authors.initials: T
authors.lastname: Clarke
authors.forename: R P
authors.initials: RP
authors.lastname: Gleeson
authors.forename: M
authors.initials: M
authors.lastname: Holohan
authors.forename: T
authors.initials: T
authors.lastname: Matthews
authors.forename: M
authors.initials: M
authors.lastname: King
authors.forename: M R
authors.initials: MR
authors.lastname: Darling
mesh_terms: D001238:Asphyxia Neonatorum / Q000150:complications / Q000401:mortality; D006801:Humans; D007231:Infant, Newborn; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D012640:Seizures / Q000209:etiology