title: [Prophylactic administration of Claforan in patients with premature loss of amniotic fluid].
abstract: The authors compared two groups of pregnant women with early loss of amniotic fluid. In the first group Claforan was administered, 3 x 1 g by the i.m. route, and in the second group Ampicillin, 3 x 1 g by the i.m. route. The data were recorded in a special protocol and were divided into three groups: 1. patient before delivery, 2. patient during puerperium, 3. neonate. From the results two conclusions were drawn: 1. The authors did not detect any reasons why antibiotics should not be administered prophylactically in case of premature loss of amniotic fluid. 2. The main differences between the compared groups were found in neonates where after administration of Claforan there was a substantially lower incidence of positive bacterial cultures than after Ampicillin and there was also a lower incidence of RDS II and adnatal infections.
authors.affiliation: II. gynek.-porod. klinika LF MU, Brno.
authors.forename: P
authors.initials: P
authors.lastname: Horký
authors.forename: D
authors.initials: D
authors.lastname: Matusková
authors.forename: A
authors.initials: A
authors.lastname: Roztocil
authors.forename: K
authors.initials: K
authors.lastname: Klimecká
authors.forename: L
authors.initials: L
authors.lastname: Pilka
mesh_terms: D000328:Adult; D000667:Ampicillin / Q000008:administration & dosage; D001424:Bacterial Infections / Q000209:etiology / Q000517:prevention & control*; D002439:Cefotaxime / Q000008:administration & dosage*; D005260:Female; D005315:Fetal Diseases / Q000209:etiology / Q000517:prevention & control*; D005322:Premature Rupture of Fetal Membranes / Q000150:complications*; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy
chemical_list: D000667:Ampicillin; D002439:Cefotaxime