title: Case holding in patients with tuberculosis in Botswana.
abstract: OBJECTIVE
  To evaluate the effectiveness of daily supervised short course chemotherapy in a national tuberculosis programme.
  
  
  METHODS
  Observation of programme during 1984-90. In October 1986 short course chemotherapy was introduced with patients receiving treatment daily from staff in their nearest health facility.
  
  
  METHODS
  Botswana national tuberculosis programme.
  
  
  METHODS
  All patients with tuberculosis.
  
  
  METHODS
  Proportions of patients complying with and defaulting from treatment (missing > or = 43 days' treatment).
  
  
  RESULTS
  2938 cases of tuberculosis were recorded in 1990, 1528 of which were of sputum positive pulmonary disease. 2711 (92.3%) patients complied with treatment and 227 (7.7%) defaulted. Before introduction of short course chemotherapy compliance was about 60% compared with over 90% in 1987-90.
  
  
  CONCLUSIONS
  A programme using daily supervised short course chemotherapy integrated into the primary health care system is an effective method of treating tuberculosis. The costs of the programme need to be evaluated.
authors.affiliation: Community Health Services Division, Epidemiology Unit, Gaborone, Botswana.
authors.forename: J A
authors.initials: JA
authors.lastname: Kumaresan
authors.forename: E T
authors.initials: ET
authors.lastname: Maganu
mesh_terms: D001902:Botswana; D004359:Drug Therapy, Combination; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use; D009313:National Health Programs; D010349:Patient Compliance; D011320:Primary Health Care; D011718:Pyrazinamide / Q000627:therapeutic use; D012293:Rifampin / Q000627:therapeutic use; D013997:Time Factors; D014376:Tuberculosis / Q000188:drug therapy*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy
chemical_list: D011718:Pyrazinamide; D007538:Isoniazid; D012293:Rifampin