Studies concerning etiology of sheep-associated malignant catarrhal fever in Europe.
The etiological agent of sheep-associated malignant catarrhal fever (MCF) in Europe has not been isolated directly from sheep. The occurrence of antibodies against the African bovine herpesvirus (BHV-3, WC 11) in cattle and sheep was examined using recently modified indirect immunofluorescence test (IIFT) and neutralization test (NT) methods. Studies revealed that sheep and cattle sera in Europe were free from neutralizing antibodies of BHV-3. The IIFT could not establish the presence of antibodies to African BHV-3 in cattle but revealed that about 22.4% of sheep sera reacted to it. Apart from the well known ovine herpesvirus (BHV-5), occurrence of another herpesvirus in Europe had been expected. This virus is not identical with the WC 11 strain, but it is in antigenic relationship to it. We had for the first time substantial serological evidence to the effect that sheep-associated MCF in Europe is a herpesvirus related to the African strain.
Muluneh
A
A
University of Leipzig-Faculty of Veterinary Medicine Institute of Microbiology and Epizootics.
Liebermann
H
H
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D005060:Europe / Q000453:epidemiology; D006564:Herpesviridae / Q000276:immunology*; D008304:Malignant Catarrh / Q000453:epidemiology / Q000382:microbiology*; D015995:Prevalence; D012756:Sheep; D012757:Sheep Diseases / Q000453:epidemiology / Q000382:microbiology*
D000914:Antibodies, Viral