Lymphadenopathy and hepatosplenomegaly in the 1st year in children infected by HIV-1 in Zaire.
The children of 50 women positive for antibody to human immunodeficiency virus type 1 (HIV-1) and 42 children of antibody-negative mothers were examined for lymphadenopathy and hepatosplenomegaly at 3-month intervals during the 1st year of life. Lymphadenopathy was found to be significantly more frequent at 6 months (p less than 0.01), 9 months (p less than 0.001) and 12 months (p less than 0.01) in children who were subsequently shown to be infected with HIV-1. Hepatomegaly was seen more frequently (p less than 0.05) in the 1st year in HIV-1-infected children than in uninfected children. Splenomegaly was not more frequent in HIV-1-infected children in this area which is holoendemic for falciparum malaria.
Jackson
D J
DJ
Department of Child Life and Health, University of Edinburgh, UK.
Klee
E B
EB
Green
S D
SD
Nganzi
M
M
Cutting
W A
WA
D015492:AIDS Serodiagnosis; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D015023:Democratic Republic of the Congo; D015497:HIV-1; D006529:Hepatomegaly / Q000150:complications; D006801:Humans; D007223:Infant; D008137:Longitudinal Studies; D008206:Lymphatic Diseases / Q000150:complications*; D013163:Splenomegaly / Q000150:complications