title: [IgM HCV antibody in chronic hepatitis and liver cirrhosis].
abstract: To evaluate the role of IgM specific antibody in the diagnosis and monitoring of the patients with chronic hepatitis C, sera from 114 cases with chronic hepatitis C and liver cirrhosis were tested. IgM antibody to hepatitis C virus was detected in 40.0% of CAH, as compared with 21.4% of CIH, 17.4% of LC, 20.0% of LC with HCC. IgM antibody was also detectable in cases with high level of s-ALT. Patients with positive this antibody have high titer of IgG antibody to hepatitis C virus. In summary, testing for this antibody may be useful to evaluate the recurrence or disease activity and may also be helpful in IFN therapy.
authors.affiliation: Department of Internal Medicine, Kitasato University School of Medicine, Sagamihara.
authors.forename: A
authors.initials: A
authors.lastname: Shibuya
authors.forename: K
authors.initials: K
authors.lastname: Sakurai
authors.forename: A
authors.initials: A
authors.lastname: Takeuchi
authors.forename: H
authors.initials: H
authors.lastname: Shibata
mesh_terms: D000328:Adult; D006508:Hepatitis Antibodies / Q000032:analysis*; D006526:Hepatitis C / Q000175:diagnosis / Q000276:immunology*; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis*; D007372:Interferons / Q000494:pharmacology; D008103:Liver Cirrhosis / Q000175:diagnosis / Q000276:immunology; D008297:Male
chemical_list: D006508:Hepatitis Antibodies; D007075:Immunoglobulin M; D007372:Interferons