title: [Swiss Register for unrelated bone marrow donors: preliminary results].
abstract: Bone marrow transplantation from the unrelated volunteer donor is today a realistic possibility for patients lacking an HLA-identical family donor. In 1988, the Swiss Unrelated Bone Marrow Donor Registry was founded to coordinate such bone marrow transplants and create the Swiss volunteer donor registry. Thus for a search has been initiated for 71 patients and 16 transplants have been performed. Donor and recipient were HLA-A-, -B- identical by serology and HLA-Dr-identical by DNA-oligotyping. 10 of the 16 patients are alive without signs of basic disease 2 weeks to 2 years and 4 months after the transplant. These results illustrate that unrelated donor transplantation, using careful selection criteria, is a realistic new therapeutic modality.
authors.affiliation: Departement Innere Medizin, Kantonsspital Basel.
authors.forename: A
authors.initials: A
authors.lastname: Gratwohl
authors.forename: C
authors.initials: C
authors.lastname: Helg
authors.forename: B
authors.initials: B
authors.lastname: Chapuis
authors.forename: J
authors.initials: J
authors.lastname: Gmür
authors.forename: M
authors.initials: M
authors.lastname: Jeannet
authors.forename: M
authors.initials: M
authors.lastname: Kern
authors.forename: A
authors.initials: A
authors.lastname: Tichelli
authors.forename: B
authors.initials: B
authors.lastname: Speck
authors.forename: E
authors.initials: E
authors.lastname: Signer
authors.forename: M
authors.initials: M
authors.lastname: Wyss
mesh_terms: D000293:Adolescent; D000328:Adult; D016026:Bone Marrow Transplantation / Q000401:mortality; D002648:Child; D002675:Child, Preschool; D005260:Female; D006680:HLA Antigens; D006650:Histocompatibility Testing / Q000379:methods; D006801:Humans; D007223:Infant; D007256:Information Systems; D007959:Lymphocyte Culture Test, Mixed; D008297:Male; D012042:Registries; D013557:Switzerland; D014019:Tissue Donors
chemical_list: D006680:HLA Antigens