title: Degradation of pentachlorophenol by Mycena avenacea TA 8480--identification of initial dechlorinated metabolites.
abstract: Cultures of the basidiomycete Mycena avenacea TA 8480 were shown to metabolize pentachlorophenol (PCP), 2,3,5,6-tetrachloro-p-hydroquinone (TeCHQ), and 2,3,5,6-tetrachloro-p-benzoquinone (TeCBQ). The first metabolite of the PCP degradation pathway was identified as TeCBQ which in a second reaction is reduced to the hydroquinone TeCHQ. Subsequently dechlorination of TeCHQ yielded 3,5,6-trichloro-2-hydroxy-p-benzoquinone (TCOHBQ). The specific degradation rate for PCP was 1.4 mg x g dry mycelia -1 x day-1. The initial dechlorination rate of TeCHQ was 5.9 mg x g dry mycelia-1 x hour-1. None of the compounds supported growth of the fungus.
authors.affiliation: Universität Kaiserslautern, LB Biotechnologie, Bundesrepublik Deutschland.
authors.forename: S
authors.initials: S
authors.lastname: Kremer
authors.forename: O
authors.initials: O
authors.lastname: Sterner
authors.forename: H
authors.initials: H
authors.lastname: Anke
mesh_terms: D001487:Basidiomycota / Q000378:metabolism*; D001711:Biotransformation; D002851:Chromatography, High Pressure Liquid; D007700:Kinetics; D010416:Pentachlorophenol / Q000378:metabolism*; D013997:Time Factors
chemical_list: D010416:Pentachlorophenol