Toxicological estimate of polyvinyl chloride containers for preparation and storage of blood, its components, preservatives and infusion solutions.
Migration of dioctyl phthalate from the polyvinyl chloride containers (PVC-containers) into blood, its components, preservatives and infusion solutions was studied for the purpose of estimating toxicity of the articles. Dependence of the plasticizer cumulation on the composition of the media found in the containers was discovered. The effect of the storage conditions on the toxicological and hygienic characteristics of the containers and intact condition of the bioproducts housed therein was investigated. Compliance of the polyvinyl chloride containers with the requirements of international standards for estimating toxicity of the polymeric materials and articles of medical purpose was established.
Lanina
S Y
SY
Strakhova
N M
NM
Lappo
V G
VG
D001803:Blood Transfusion / Q000295:instrumentation*; D004051:Diethylhexyl Phthalate / Q000493:pharmacokinetics; D004349:Drug Packaging / Q000592:standards*; D005069:Evaluation Studies as Topic; D006801:Humans; D007262:Infusions, Intravenous / Q000295:instrumentation*; D011143:Polyvinyl Chloride / Q000737:chemistry / Q000633:toxicity*; D014021:Tissue Preservation / Q000295:instrumentation* / Q000379:methods / Q000592:standards
D011143:Polyvinyl Chloride; D004051:Diethylhexyl Phthalate