Erythrocyte macrocytosis in infants and children with Down syndrome.
Erythrocyte mean corpuscular volume and mean corpuscular hemoglobin levels were higher in children with Down syndrome than in normal control subjects. Reference values for mean corpuscular volume and mean corpuscular hemoglobin level derived from normal populations may be inappropriate for children with Down syndrome. These findings may have important implications for the diagnosis of iron deficiency in these children.
Starc
T J
TJ
Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, New York.
D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000097:blood* / Q000150:complications; D004909:Erythrocyte Indices; D004913:Erythrocytes, Abnormal; D006330:Heart Defects, Congenital / Q000097:blood / Q000150:complications; D006801:Humans; D007223:Infant