Toxicological aspects of preclinical studies of hemosorbents.
The main tendencies in the development of methods for hemo- and lymphosorption are considered. Base toxicological requirements to sorbents have been formulated. Special attention is paid to possible tox effects of sorbents containing carcinogenic admixtures. The importance of choosing appropriate methods sorbents' sterilization or conservation has been emphasized. Results of studies of various sorbents a presented.
Timokhina
V I
VI
Lanina SYa
Lappo
V G
VG
D000818:Animals; D004353:Drug Evaluation, Preclinical; D006464:Hemoperfusion / Q000009:adverse effects* / Q000379:methods / Q000592:standards; D013242:Sterilization / Q000379:methods / Q000592:standards