title: Influence of age on the febrile response to E. coli and S. typhimurium endotoxins in growing pullets.
abstract: 1. The effect of bacterial endotoxin injection was studied in growing pullets of different ages. Commercial chicks were divided into 5 groups according to age. Bacterial endotoxins (E. coli and S. typhimurium) were injected intravenously and rectal temperature was measured over a period of 300 min. 2. The results showed no significant effect of age on the febrile response induced by bacterial endotoxins, but a slight tendency towards a reduced fever peak was observed with increasing age. The response latency also increased with age.
authors.affiliation: Departamento de Morfologia e Fisiologia Animal, Faculdade de Ciências Agrárias e Veterinárias, UNESP, Brazil.
authors.forename: F P
authors.initials: FP
authors.lastname: Gregorut
authors.forename: L C
authors.initials: LC
authors.lastname: Baptista
authors.forename: A S
authors.initials: AS
authors.lastname: Paulim
authors.forename: J R
authors.initials: JR
authors.lastname: Guerreiro
authors.forename: E R
authors.initials: ER
authors.lastname: Secato
authors.forename: M
authors.initials: M
authors.lastname: Macari
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D002645:Chickens / Q000502:physiology*; D004731:Endotoxins / Q000009:adverse effects*; D004926:Escherichia coli / Q000472:pathogenicity; D005334:Fever / Q000382:microbiology / Q000503:physiopathology / Q000662:veterinary*; D007267:Injections; D011201:Poultry Diseases / Q000382:microbiology / Q000503:physiopathology*; D012486:Salmonella typhimurium / Q000472:pathogenicity
chemical_list: D004731:Endotoxins