[The results of the chemoembolization of advanced hepatocellular carcinomas. The effect on the survival times, morphological findings and tumor markers].
Chemoembolization is a well-recognized therapeutic procedure in the treatment of stage I and stage II hepatocellular carcinoma (HCC). Until now it is rarely used in the treatment of stage III HCC. In a prospective study we analysed the efficacy and the side effects of chemoembolization in 16 patients with stage III HCC. Chemoembolization was performed with an emulsion of lipiodol, 4-epirubicin and cisplatinum. All patients tolerated the treatment without remarkable complications. With 9 months the median survival rate was considerable higher than the survival rate of untreated patients and of patients treated with systemic chemotherapy or with local perfusion.
Wickenhöfer
R
R
Radiologische Klinik, Rheinische Friedrich-Wilhelms-Universität, Bonn.
Hasan
I
I
Schüller
H
H
Reiser
M
M
Hartlapp
J H
JH
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D014408:Biomarkers, Tumor / Q000097:blood*; D006528:Carcinoma, Hepatocellular / Q000097:blood / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D016461:Chemoembolization, Therapeutic; D002945:Cisplatin / Q000008:administration & dosage; D015251:Epirubicin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007459:Iodized Oil / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000097:blood / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011446:Prospective Studies; D012074:Remission Induction; D016019:Survival Analysis; D000509:alpha-Fetoproteins / Q000032:analysis*
D014408:Biomarkers, Tumor; D000509:alpha-Fetoproteins; D015251:Epirubicin; D007459:Iodized Oil; D002945:Cisplatin