Incorporation of carotenoids in aqueous systems: uptake by cultured rat hepatocytes.
The in vitro investigations about carotenoid functions and metabolism are hindered by their hydrophobicity. In order to mimic as close as possible the physiological events, we prepared by rapid and easy methods sterile liposomes and emulsions containing carotenoids which are absorbed by cultured rat hepatocytes as a function of time and temperature. The lipid composition of the vesicles was shown to influence the carotenoid encapsulation.
Grolier
P
P
Laboratoire de Nutrition et Sécurité Alimentaire, INRA, CRJ, Jouy-en-Josas, France.
Azaïs-Braesco
V
V
Zelmire
L
L
Fessi
H
H
D000818:Animals; D002338:Carotenoids / Q000493:pharmacokinetics*; D002478:Cells, Cultured; D004655:Emulsions; D004705:Endocytosis; D008081:Liposomes / Q000378:metabolism; D008099:Liver / Q000378:metabolism*; D051381:Rats
D004655:Emulsions; D008081:Liposomes; D002338:Carotenoids