title: Tissue responses to Hydron, assessed by intraosseous implantation.
abstract: Teflon tubes containing freshly mixed, polymerized Hydron root canal filling material, fully set AH26 or Teflon were implanted into the mandible of guinea pigs and assessed histologically at 2 days, 1, 2, 4, 12 and 26 weeks. None of the materials tested elicited signs of overt or significant tissue damage, and polymerized Hydron was assessed to be as biocompatible as fully set AH26 and Teflon. Bone formed in very close apposition to the polymerized Hydron, whereas a soft tissue capsule separated the regenerated bone from implants of AH26 and Teflon.
authors.affiliation: The University of Adelaide, South Australia.
authors.forename: R J
authors.initials: RJ
authors.lastname: Reid
authors.forename: D F
authors.initials: DF
authors.lastname: Wilson
authors.forename: K K
authors.initials: KK
authors.lastname: Chau
authors.forename: G S
authors.initials: GS
authors.lastname: Heithersay
authors.forename: P S
authors.initials: PS
authors.lastname: Heijkoop
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001729:Bismuth / Q000633:toxicity; D001861:Bone Regeneration / Q000187:drug effects*; D001842:Bone and Bones / Q000187:drug effects; D004338:Drug Combinations; D004853:Epoxy Resins; D006168:Guinea Pigs; D020100:Hydrogels; D008297:Male; D008422:Materials Testing; D008709:Methenamine / Q000633:toxicity; D011102:Polyhydroxyethyl Methacrylate / Q000031:analogs & derivatives* / Q000633:toxicity; D011138:Polytetrafluoroethylene / Q000633:toxicity; D019736:Prostheses and Implants; D012387:Root Canal Filling Materials / Q000633:toxicity*; D012834:Silver / Q000633:toxicity; D014025:Titanium / Q000633:toxicity; D014945:Wound Healing / Q000187:drug effects
chemical_list: D001672:Biocompatible Materials; D004338:Drug Combinations; D004853:Epoxy Resins; D020100:Hydrogels; D012387:Root Canal Filling Materials; C000257:polyhydroxyethyl methacrylate hydrogels; D011102:Polyhydroxyethyl Methacrylate; D012834:Silver; C028044:epoxy resin AH-26; D011138:Polytetrafluoroethylene; D014025:Titanium; D008709:Methenamine; D001729:Bismuth