Ion channel activity and transmembrane signaling in lymphocytes.
Transmembrane signalling refers to the process of transfer of information from the extracellular world into the intracellular space. The information is transduced through several possible pathways. The significance of cell surface dynamics, ion channel activity and drug effects are discussed in the signal transmission, with special reference to Na+ channels and the Ca2+ sensitive potassium channels.
Damjanovich
S
S
Department of Biophysics, University Medical School of Debrecen, Hungary.
Pieri
C
C
Trón
L
L
D000818:Animals; D001950:Bretylium Tosylate / Q000494:pharmacology; D002462:Cell Membrane / Q000502:physiology; D016572:Cyclosporine / Q000494:pharmacology; D006801:Humans; D015640:Ion Channel Gating; D007473:Ion Channels / Q000502:physiology*; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000502:physiology*; D008564:Membrane Potentials; D015290:Second Messenger Systems; D015398:Signal Transduction / Q000187:drug effects
D007473:Ion Channels; D001950:Bretylium Tosylate; D016572:Cyclosporine