Prognostic assessment of fulminant hepatitis from indication criteria for liver transplantation.
The clinical outcome in 15 patients with fulminant hepatitis was predicted by the indication criteria for liver transplantation used in five different transplantation centers. Fifty-four to 100% of 13 fulminant hepatitis patients died who were fulfilled with these criteria for transplantation. Most of the patients died within five to nine days after the decision of liver transplantation was made. Takahashi's score of prognostic assessment for fulminant hepatitis decreased rapidly during the time when all the different criteria in transplantation centers were fulfilled. However, two survival cases with the acute type of fulminant hepatitis were incorrectly judged to be transplanted by the two criteria. The Cambridge's criterion for liver transplantation predicted the prognosis of fulminant hepatitis most correctly; sensitivity was 84.6% and specificity 100%.
Watanabe
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A
Third Department of Internal Medicine, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Japan.
Shiota
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T
Tsuji
T
T
D000208:Acute Disease; D000328:Adult; D000368:Aged; D001663:Bilirubin / Q000097:blood; D005260:Female; D006501:Hepatic Encephalopathy / Q000097:blood / Q000401:mortality* / Q000517:prevention & control / Q000601:surgery; D006801:Humans; D016031:Liver Transplantation / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011517:Prothrombin Time; D012720:Severity of Illness Index; D000509:alpha-Fetoproteins / Q000032:analysis
D000509:alpha-Fetoproteins; D001663:Bilirubin