Galanin inhibits sexual behavior in male rats.
Intracerebroventricular injection of galanin potently inhibited (0.5 micrograms/rat) or completely suppressed (5.0 micrograms/rat) copulatory activity in sexually experienced male rats, without producing any other obvious behavioral deficit. It is suggested that galanin, known to potently stimulate feeding behavior, may be involved in the inverse modulation of feeding and sexual behaviors.
Poggioli
R
R
Institute of Pharmacology, University of Modena, Italy.
Rasori
E
E
Bertolini
A
A
D000818:Animals; D005247:Feeding Behavior / Q000187:drug effects; D005260:Female; D019004:Galanin; D007276:Injections, Intraventricular; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D010455:Peptides / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D012726:Sexual Behavior, Animal / Q000187:drug effects*
D010455:Peptides; D019004:Galanin