Rostral cerebellar malformation, (rcm): a new recessive mutation on chromosome 3 of the mouse.
A new recessive mutation in the mouse that causes a disorderly arrangement of Purkinje and granule cells in the rostral portion of the cerebellum is described. The mutation, called rostral cerebellar malformation, rcm, has been located on chromosome (Chr) 3 between the alcohol dehydrogenase-3 (Adh-3) complex and varitint waddler-J (VaJ).
Lane
P W
PW
Jackson Laboratory, Bar Harbor, Maine.
Bronson
R T
RT
Spencer
C A
CA
D000818:Animals; D002531:Cerebellum / Q000002:abnormalities*; D002874:Chromosome Mapping; D000013:Congenital Abnormalities / Q000235:genetics; D003433:Crosses, Genetic; D005260:Female; D005808:Genes, Recessive; D008040:Genetic Linkage; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009154:Mutation