Delivery systems for angiogenesis stimulators and inhibitors.
The development of biocompatible, controlled release systems for macromolecules has provided the opportunity to deliver angiogenesis stimulators and inhibitors. These systems have also facilitated the purification and characterization of a number of these substances. In this paper, we discuss controlled release delivery systems which release angiogenesis factors through either porous polymer matrices, degradable polymeric delivery systems or modulated polymer release systems.
Langer
R
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MIT E25-342, Department of Chemical Engineering, Cambridge, MA 02139.
D000818:Animals; D001672:Biocompatible Materials; D001673:Biodegradation, Environmental; D004337:Drug Carriers; D006133:Growth Substances / Q000008:administration & dosage*; D006801:Humans; D009389:Neovascularization, Pathologic / Q000473:pathology / Q000503:physiopathology*; D011108:Polymers
D001672:Biocompatible Materials; D004337:Drug Carriers; D006133:Growth Substances; D011108:Polymers