CD45 regulates TCR-induced signalling through tyrosine phosphorylation of phospholipase C gamma 1.
Kanner
S B
SB
Bristol-Myers Squibb Pharmaceutical Research Institute, Seattle, WA 98121.
Ledbetter
J A
JA
D000818:Animals; D015703:Antigens, CD / Q000502:physiology*; D002460:Cell Line; D006649:Histocompatibility Antigens / Q000502:physiology*; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism*; D017493:Leukocyte Common Antigens; D008562:Membrane Glycoproteins / Q000502:physiology; D010766:Phosphorylation; D011948:Receptors, Antigen, T-Cell / Q000502:physiology*; D015398:Signal Transduction; D010738:Type C Phospholipases / Q000378:metabolism*
D015703:Antigens, CD; D006649:Histocompatibility Antigens; D007527:Isoenzymes; D008562:Membrane Glycoproteins; D011948:Receptors, Antigen, T-Cell; D017493:Leukocyte Common Antigens; D010738:Type C Phospholipases