title: Sequence of the complete osp operon encoding two major outer membrane proteins of a European Borrelia burgdorferi isolate (B29)
abstract: The nucleotide sequence of the operon encoding the major outer surface proteins, OspA and OspB, of a European isolate of Borrelia burgdorferi (strain B29) was determined and compared to the osp operon of the American strain, B31. An amino acid (aa) identity of 80.7% was found when comparing the OspA of B29 with that of B31, whereas the aa sequence of the OspB of B29 reveals only 61.3% identity with the OspB of B31. Thus, strains B31 and B29 can be regarded as representatives of different B. burgdorferi groups.
authors.affiliation: Institut für Mikrobiologie (Med. Fak.), Universität Innsbruck, Austria.
authors.forename: W
authors.initials: W
authors.lastname: Fellinger
authors.forename: B
authors.initials: B
authors.lastname: Redl
authors.forename: G
authors.initials: G
authors.lastname: Stöffler
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000954:Antigens, Surface / Q000737:chemistry / Q000235:genetics*; D001425:Bacterial Outer Membrane Proteins / Q000737:chemistry / Q000235:genetics*; D001428:Bacterial Vaccines; D001483:Base Sequence; D015748:Borrelia burgdorferi Group / Q000235:genetics*; D005060:Europe; D005260:Female; D008074:Lipoproteins; D008969:Molecular Sequence Data; D017386:Sequence Homology, Amino Acid; D013987:Ticks / Q000382:microbiology
chemical_list: D000954:Antigens, Surface; D001425:Bacterial Outer Membrane Proteins; D001428:Bacterial Vaccines; D008074:Lipoproteins; C072045:OspA protein