Doxazosin in the management of hypertensive diabetes--a cautionary note (?).
Twenty-two patients with diabetes and hypertension were treated with Doxazosin. An acceptable fall in blood pressure was found with 1 mg. in 50% of patients and 2-8 mgs. in 50%. An increase in HDL cholesterol and a fall in LDL cholesterol levels which reached statistical significance was observed. A small but significant increase in HBA1 levels occurred in the 50% of patients on the higher Doxazosin dose.
McLaughlin
B
B
Department of Endocrinology, Beaumont Hospital, Dublin.
Daly
L
L
Devlin
J G
JG
D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000097:blood; D017292:Doxazosin; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D008875:Middle Aged; D011224:Prazosin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use
D000959:Antihypertensive Agents; D017292:Doxazosin; D011224:Prazosin