[Steroid and protein hormone concentrations in serum and follicular fluid after stimulation for in vitro fertilization].
Sixty patients with tubal infertility were stimulated for IVF with a fixed schedule consisting of clomiphene and pure follicle stimulating hormone. They responded with an optimal estradiol increase and 2 to 4 embryos were transferred. Conception cycles (n = 17) could be differentiated from non-conception cycles (n = 43) by serum estradiol, serum progesterone, the serum progesterone/estradiol-ratio and serum LH concentrations. Testosterone, androstenedione and FSH in serum and follicular fluid showed no significant relation to a possible therapy outcome. We conclude from our findings, that, during the peri-implantation period, certain LH patterns followed by an optimal progesterone/estradiol-ratio in the serum support an embryo survival after transfer to the uterus.
Zech
H
H
Institut für In-Vitro-Fertilisierung und Embryo-Transfer, Bregenz.
Weiss
P
P
Fritzsche
H
H
Zech
J
J
Daxenbichler
G
G
D000735:Androstenedione / Q000097:blood; D004958:Estradiol / Q000097:blood; D005260:Female; D005307:Fertilization in Vitro; D005640:Follicle Stimulating Hormone / Q000097:blood; D015571:Follicular Fluid / Q000502:physiology*; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006801:Humans; D007247:Infertility, Female / Q000097:blood* / Q000628:therapy; D007986:Luteinizing Hormone / Q000097:blood; D010062:Ovulation Induction; D011247:Pregnancy; D011374:Progesterone / Q000097:blood; D013739:Testosterone / Q000097:blood
D012739:Gonadal Steroid Hormones; D013739:Testosterone; D000735:Androstenedione; D011374:Progesterone; D004958:Estradiol; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone