IgE-mediated reaction to vancomycin and teicoplanin after treatment with vancomycin.
A 38-year-old male patient developed severe signs of type 1 allergy after treatment with vancomycin. By the basophil histamine release test, the patient's isolated basophil leucocytes were shown to react IgE dependent after challenge with vancomycin and teicoplanin. This indicates that the patient is type 1 allergic towards vancomycin and teicoplanin.
Knudsen
J D
JD
Department of Clinical Microbiology, Rigshospitalet, Copenhagen, Denmark.
Pedersen
M
M
D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000276:immunology*; D006020:Glycopeptides / Q000009:adverse effects / Q000276:immunology; D006636:Histamine Release / Q000187:drug effects; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D008297:Male; D017334:Teicoplanin; D014640:Vancomycin / Q000009:adverse effects* / Q000276:immunology
D000900:Anti-Bacterial Agents; D006020:Glycopeptides; D007073:Immunoglobulin E; D017334:Teicoplanin; D014640:Vancomycin