The study cellular subpopulations in peripheral blood from a normal reference group population (blood donors).
The spectacular development of monoclonal antibodies against cellular antigens an technology such as flow cytometry allow the investigation of cellular subpopulations that until now have been unknown. At the same time, the functional study of these subpopulations becomes of maximal interest, as this information could have future applications for pathological processes. Due ti this basic need for information, we have studied diverse lymphocytic subpopulations in a normal population that serves as a reference group, using the following antigens: CD3, CD4, CD8, CD20, CD45RA, CD25, LAM1, CD29, CD11b and CD23. Some of these subpopulations had not been previously studied in a normal reference group.
Monteseirín
J
J
Servicio de Inmunología y Alergia, Hospital Universitario Virgen Macarena, Sevilla, España.
Llamas
E
E
Bobadilla
P
P
Delgado
J
J
Jiménez
M J
MJ
Conde
J
J
D000911:Antibodies, Monoclonal / Q000276:immunology; D015703:Antigens, CD / Q000032:analysis; D001782:Blood Donors; D015815:Cell Adhesion Molecules / Q000032:analysis; D019040:E-Selectin; D005434:Flow Cytometry; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D016130:Immunophenotyping; D016131:Lymphocyte Subsets; D012016:Reference Values
D000911:Antibodies, Monoclonal; D015703:Antigens, CD; D015815:Cell Adhesion Molecules; D019040:E-Selectin; D007073:Immunoglobulin E