Endometrial stromal nodule with smooth and skeletal muscle components simulating stromal sarcoma.
A stromal nodule was found in a hysterectomy specimen from a 29-year-old woman with a history of menometrorrhagia. Endometrial curettings had revealed stromal cells admixed with well-defined bundles of smooth muscle cells, a finding that had led to the erroneous diagnosis of stromal sarcoma invading the myometrium. Ultrastructural and immunohistochemical studies demonstrated several components: stromal cells, smooth muscle cells, sex-cord-like structures, and a hitherto undescribed component of skeletal muscle cells.
Lloreta
J
J
Department of Pathology, Hospital de Sant Pau, Barcelona, Spain.
Prat
J
J
D000328:Adult; D003937:Diagnosis, Differential; D016889:Endometrial Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D009379:Neoplasms, Muscle Tissue / Q000473:pathology* / Q000648:ultrastructure; D012509:Sarcoma / Q000473:pathology* / Q000648:ultrastructure; D017154:Stromal Cells / Q000473:pathology* / Q000648:ultrastructure