Serine/threonine protein kinases.
Signal transduction in the nervous system is heavily dependent on the three multifunctional serine/threonine protein kinases, PKA, PKC, and CaM-KII. Recent studies have furthered our understanding of how the multiple isoforms of these kinases and their subcellular localizations, regulatory properties, and substrate determinants are important for the specificity of kinase functions.
Scott
J D
JD
Vollum Institute for Advanced Biomedical Research, Oregon Health Sciences University, Portland 97201.
Soderling
T R
TR
D000818:Animals; D006801:Humans; D011494:Protein Kinases / Q000502:physiology*; D017346:Protein Serine-Threonine Kinases; D015398:Signal Transduction / Q000502:physiology*
D011494:Protein Kinases; D017346:Protein Serine-Threonine Kinases