Reversal of radiation-induced neutropenia by granulocyte colony-stimulating factor.
Myelosuppression is a common sequelae of radiotherapy, occasionally delaying the completion of treatment. In this report, we describe successful reversal of radiation-induced neutropenia in a child receiving craniospinal irradiation by granulocyte colony-stimulating factor (G-CSF). We suggest that G-CSF be considered as supportive care in patients in whom neutropenia develops during radiotherapy.
Marks
L B
LB
Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710.
Friedman
H S
HS
Kurtzberg
J
J
Oakes
W J
WJ
Hockenberger
B M
BM
D002528:Cerebellar Neoplasms / Q000532:radiotherapy; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D008297:Male; D008527:Medulloblastoma / Q000532:radiotherapy; D009503:Neutropenia / Q000188:drug therapy* / Q000209:etiology; D011878:Radiotherapy / Q000009:adverse effects
D016179:Granulocyte Colony-Stimulating Factor