title: Prospects for the genetic engineering of milk.
abstract: Milk and milk products comprise a substantial fraction of the protein intake of the industrialised West. The establishment of germline manipulation techniques in cows offers opportunities for directly manipulating milk composition to produce products with enhanced nutritional and processing properties. The major milk proteins are encoded by a small number of abundantly expressed single-copy genes and a number of possible manipulations are described. Milk proteins exhibit complex interactions with each other and with other constituents of milk. It will, therefore, be necessary to utilise model systems to evaluate the consequences of these proposed changes before embarking upon the costly and time-consuming process of manipulating the bovine genome.
authors.affiliation: AFRC Institute of Animal Physiology and Genetics Research, Edinburgh Research Station, Roslin, Midlothian, United Kingdom.
authors.forename: A J
authors.initials: AJ
authors.lastname: Clark
mesh_terms: D000818:Animals; D002417:Cattle; D003612:Dairying / Q000379:methods; D005525:Food-Processing Industry / Q000379:methods; D005818:Genetic Engineering / Q000379:methods* / Q000639:trends; D051379:Mice; D008894:Milk Proteins / Q000096:biosynthesis* / Q000235:genetics
chemical_list: D008894:Milk Proteins