[Measurement of superoxide dismutase activity in the blood of radiation workers].
In this study, we measured the superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase GPX) activities in the peripheral blood of radiation workers (111 cases) and the controls (108 cases), also analyzed chromosome aberrations in blood lymphocytes by means of G-banding technique. The chromosome deletions were not found in the controls. There were 7 cases chromosome deletions found by G-banding in 111 cases of radiation workers, their SOD activities were markedly lower than those in the controls (P less than 0.05). SOD and CAT activities in the other 104 cases of radiation workers were significantly higher than those in the controls (P less than 0.01). But there was no difference of GPX activity between the radiation workers and the controls. However, increase of SOD activity mainly occurred in radiation workers who were exposed to radiation over 0.0177 +/- 0.0032 Gy. The possible mechanism of this phenomenon was discussed.
Luo
S W
SW
Department of Biochemistry, Yichun Medical College, Jiangxi.
D000328:Adult; D000368:Aged; D002374:Catalase / Q000097:blood; D002872:Chromosome Deletion; D005260:Female; D005979:Glutathione Peroxidase / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D011827:Radiation; D011832:Radiation Injuries / Q000201:enzymology; D013482:Superoxide Dismutase / Q000097:blood*
D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase