title: The California Maternal Serum alpha-Fetoprotein Screening Program: the role of ultrasonography in the detection of spina bifida.
abstract: Between January 1988 and June 1990, 161 cases of open spina bifida were identified by the California Maternal Serum alpha-Fetoprotein Screening Program. Eight percent of these cases were not diagnosed by an initial ultrasonographic evaluation. Three defects were not recognized until birth. Ultrasonography is inadequate to identify all cases of open spina bifida.
authors.affiliation: Department of Obstetrics and Gynecology, Cedars-Sinai Medical Center, University of California Los Angeles School of Medicine 90048-1869.
authors.forename: L D
authors.initials: LD
authors.lastname: Platt
authors.forename: L
authors.initials: L
authors.lastname: Feuchtbaum
authors.forename: R
authors.initials: R
authors.lastname: Filly
authors.forename: L
authors.initials: L
authors.lastname: Lustig
authors.forename: M
authors.initials: M
authors.lastname: Simon
authors.forename: G C
authors.initials: GC
authors.lastname: Cunningham
mesh_terms: D002140:California; D005260:Female; D006801:Humans; D011247:Pregnancy; D011296:Prenatal Diagnosis; D016135:Spinal Dysraphism / Q000175:diagnosis* / Q000000981:diagnostic imaging; D014463:Ultrasonography; D000509:alpha-Fetoproteins / Q000032:analysis*
chemical_list: D000509:alpha-Fetoproteins