Carboplatin and retroperitoneal fibrosis.
A patient treated for ovarian epithelial cancer by total abdominal hysterectomy (TAH), bilateral salpingo-oophorectomy (BSO), total omentectomy and five courses of single agent carboplatin chemotherapy, developed retroperitoneal fibrosis. This was diagnosed at exploratory laparotomy 6 months after completing treatment. No predisposing drug history existed in this patient. We believe that there have been no previous reports of an association between retro peritoneal fibrosis and carboplatin treatment.
Adab
F A
FA
Department of Radiotherapy and Oncology, Queen Elizabeth Hospital, Birmingham, UK.
Mould
J J
JJ
D016190:Carboplatin / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy; D011859:Radiography; D012185:Retroperitoneal Fibrosis / Q000139:chemically induced* / Q000000981:diagnostic imaging
D016190:Carboplatin