title: Gas gangrene following intra-arterial injection of oral medication in a drug abuser.
abstract: We report a patient in whom intra-arterial injection of oral medication led to the development of fulminating gas gangrene and death, despite the initial clinical symptoms being minor. We believe that prophylactic antibiotics should be administered to patients following intra-arterial injection of oral medication especially if immunocompetence, such as from human immunodeficiency virus (HIV) infection, is likely.
authors.affiliation: Vascular Surgery Unit, Royal Infirmary, Edinburgh, U.K.
authors.forename: D C
authors.initials: DC
authors.lastname: Haiart
authors.forename: B
authors.initials: B
authors.lastname: Andrade
authors.forename: J A
authors.initials: JA
authors.lastname: Murie
mesh_terms: D000059:Accidents; D000328:Adult; D000818:Animals; D003501:Cyclizine / Q000008:administration & dosage / Q000009:adverse effects*; D005263:Femoral Artery; D005738:Gas Gangrene / Q000139:chemically induced* / Q000000981:diagnostic imaging; D006801:Humans; D007269:Injections, Intra-Arterial; D008297:Male; D011859:Radiography; D015819:Substance Abuse, Intravenous; D013607:Tablets; D014229:Triazolam / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D013607:Tablets; D014229:Triazolam; D003501:Cyclizine