title: Reversal of radiation-induced neutropenia by granulocyte colony-stimulating factor.
abstract: Myelosuppression is a common sequelae of radiotherapy, occasionally delaying the completion of treatment. In this report, we describe successful reversal of radiation-induced neutropenia in a child receiving craniospinal irradiation by granulocyte colony-stimulating factor (G-CSF). We suggest that G-CSF be considered as supportive care in patients in whom neutropenia develops during radiotherapy.
authors.affiliation: Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710.
authors.forename: L B
authors.initials: LB
authors.lastname: Marks
authors.forename: H S
authors.initials: HS
authors.lastname: Friedman
authors.forename: J
authors.initials: J
authors.lastname: Kurtzberg
authors.forename: W J
authors.initials: WJ
authors.lastname: Oakes
authors.forename: B M
authors.initials: BM
authors.lastname: Hockenberger
mesh_terms: D002528:Cerebellar Neoplasms / Q000532:radiotherapy; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D008297:Male; D008527:Medulloblastoma / Q000532:radiotherapy; D009503:Neutropenia / Q000188:drug therapy* / Q000209:etiology; D011878:Radiotherapy / Q000009:adverse effects
chemical_list: D016179:Granulocyte Colony-Stimulating Factor