New polyenic antibiotics active against gram-positive and gram-negative bacteria. VI. Non-lactonic polyene antibiotic, enacyloxin IIa, inhibits binding of aminoacyl-tRNA to A site of ribosomes.
Watanabe
T
T
Department of Agricultural Chemistry, Faculty of Agriculture, Tohoku University, Sendai, Japan.
Okubo
N
N
Suzuki
T
T
Izaki
K
K
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D011090:Polyenes / Q000494:pharmacology; D012329:RNA, Bacterial; D012333:RNA, Messenger / Q000378:metabolism; D012346:RNA, Transfer, Amino Acyl / Q000187:drug effects* / Q000378:metabolism; D012360:RNA, Transfer, Phe / Q000378:metabolism; D012270:Ribosomes / Q000187:drug effects* / Q000378:metabolism
D000900:Anti-Bacterial Agents; D011090:Polyenes; D012329:RNA, Bacterial; D012333:RNA, Messenger; D012346:RNA, Transfer, Amino Acyl; D012360:RNA, Transfer, Phe; C072734:enacyloxin IIa