title: Synthesis of lysine-containing fragments of the Proteus mirabilis O27 O-specific polysaccharide and neoglycoconjugates therefrom.
abstract: Amide-linked lysine mono- and di-uronic acid fragments of the O-specific polysaccharide from P. mirabilis O27 have been synthesised. N epsilon-Boc-L-lysine tert-butyl ester was condensed with 2-azidoethyl glycosides of glucuronic acid and beta-D-GlcpNAc-(1----3)-beta-D-GlcpA. Transformation of the products into 2-acrylamidoethyl glycosides, followed by deprotection using trifluoroacetic acid, gave the target monomers that were converted into high-molecular-weight copolymer-type neoglycoconjugates.
authors.affiliation: N. D. Zelinsky Institute of Organic Chemistry, Academy of Sciences of the U.S.S.R., Moscow.
authors.lastname: Chernyak AYa
authors.forename: L O
authors.initials: LO
authors.lastname: Kononov
authors.forename: P R
authors.initials: PR
authors.lastname: Krishna
authors.forename: N K
authors.initials: NK
authors.lastname: Kochetkov
authors.forename: A V
authors.initials: AV
authors.lastname: Rao
mesh_terms: D002240:Carbohydrate Sequence; D006001:Glycoconjugates / Q000138:chemical synthesis*; D008239:Lysine / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D019081:O Antigens; D011135:Polysaccharides, Bacterial / Q000737:chemistry*; D011513:Proteus mirabilis / Q000737:chemistry*
chemical_list: D006001:Glycoconjugates; D019081:O Antigens; D011135:Polysaccharides, Bacterial; D008239:Lysine