title: A case of adult T cell leukemia with bullae in the palmoplantar regions followed by a crisis.
abstract: A 48-year-old Japanese female who had had chronic ATL for 4 years suddenly developed vesicles on the palms and soles. Histologically, these bullae were specific lesions of ATL. After a tendency toward improvement, a crisis appeared with increases in the following: peripheral white blood cells, atypical lymphocytes, CD25 positive cells, serum LDH, and soluble IL-2R. Palmoplantar bullae, a rather rare finding, may be indicative of a following crisis.
authors.affiliation: Department of Dermatology, Kumamoto University Medical School, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Yoshimura
authors.forename: M
authors.initials: M
authors.lastname: Oishi
authors.forename: M
authors.initials: M
authors.lastname: Johno
authors.forename: T
authors.initials: T
authors.lastname: Ono
mesh_terms: D005260:Female; D005533:Foot Dermatoses / Q000473:pathology*; D006229:Hand Dermatoses / Q000473:pathology*; D006801:Humans; D015458:Leukemia, T-Cell / Q000150:complications* / Q000473:pathology; D008875:Middle Aged; D012872:Skin Diseases, Vesiculobullous / Q000150:complications / Q000473:pathology*