title: Gender differences in the clinical expression of schizophrenia.
abstract: Gender differences have been reported for a variety of clinical measures in patients with schizophrenia. Clinical characterization may be helpful in identifying symptom clusters which can then be linked to underlying brain function. In this study 74 men and 33 women meeting DSM-IIIR criteria for schizophrenia were studied off medication and rated on measures of symptom type and severity, as well as premorbid and current function. Men were more severely impaired in ratings of negative symptoms, while positive symptoms were not significantly different. There were also differences in premorbid and current functioning, with women manifesting better social functioning than men.
authors.affiliation: Department of Psychiatry, University of Pennsylvania, Philadelphia 19104.
authors.forename: D L
authors.initials: DL
authors.lastname: Shtasel
authors.forename: R E
authors.initials: RE
authors.lastname: Gur
authors.forename: F
authors.initials: F
authors.lastname: Gallacher
authors.forename: C
authors.initials: C
authors.lastname: Heimberg
authors.forename: R C
authors.initials: RC
authors.lastname: Gur
mesh_terms: D000203:Activities of Daily Living / Q000523:psychology; D000328:Adult; D000342:Affective Symptoms / Q000175:diagnosis / Q000523:psychology; D005260:Female; D005783:Gender Identity; D006801:Humans; D008297:Male; D010553:Personality Development; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life; D012559:Schizophrenia / Q000175:diagnosis* / Q000534:rehabilitation; D012565:Schizophrenic Psychology; D012917:Social Adjustment