title: Myasthenia gravis-like syndrome induced by topical ophthalmic preparations. A case report.
abstract: This case study reports on a 64-year-old female who presented for cataract surgery. She relayed a history of allergic responses to local anesthetics such as xylocaine, but was otherwise in good health. Upon instilling ophthalmic preparations into her eyes during routine ocular examination, she developed general muscular weakness but not other allergic-like symptoms. Further investigation established her myasthenic-like syndrome to be precipitated by an ophthalmic mydriatic preparation. She was able to undergo uneventful cataract surgery and enjoy 20/20 vision postoperatively, with proper management.
authors.affiliation: Gimbel Eye Center, Calgary, Alberta, Canada.
authors.forename: D
authors.initials: D
authors.lastname: Meyer
authors.forename: R C
authors.initials: RC
authors.lastname: Hamilton
authors.forename: H V
authors.initials: HV
authors.lastname: Gimbel
mesh_terms: D002387:Cataract Extraction; D005260:Female; D006801:Humans; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000139:chemically induced*; D009883:Ophthalmic Solutions / Q000009:adverse effects; D011430:Propoxycaine / Q000009:adverse effects*; D013577:Syndrome; D014331:Tropicamide / Q000009:adverse effects*
chemical_list: D009883:Ophthalmic Solutions; C005717:proxymetacaine; D011430:Propoxycaine; D014331:Tropicamide