4-acetylaplykurodin B and aplykurodinone B, two ichthyotoxic degraded sterols from the Mediterranean mollusk Aplysia fasciata.
Two ichthyotoxic lactones, 4-acetylaplykurodin B [1] and aplykurodinone B [2], were isolated from the external parts of the body of the mollusk Aplysia fasciata. Their structures, determined by spectroscopic and chemical means, are closely related to aplykurodin B [3] previously isolated from Aplysia kurodai. The interconversion of delta- and gamma-lactones in the aplykurodin derivatives has been also investigated.
Spinella
A
A
Istituto per la Chimica di Molecole di Interesse Biologico, C.N.R., Arco Felice, Italy.
Gavagnin
M
M
Crispino
A
A
Cimino
G
G
Martinez
E
E
Ortea
J
J
Sodano
G
G
D000818:Animals; D001048:Aplysia / Q000737:chemistry*; D007189:Indans / Q000737:chemistry* / Q000302:isolation & purification; D007783:Lactones / Q000737:chemistry* / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D015394:Molecular Structure; D009904:Optical Rotation
D007189:Indans; D007783:Lactones; C077372:4-acetylaplykurodin B; C077373:aplykurodinone B