Antimutagenicity in yeast.
In recent years there has been increasing interest in antimutagenesis, and studies have been done using both prokaryotic and eukaryotic systems. In eukaryotic systems the first studies were performed with different strains of Schizosaccharomyces pombe. In particular, caffeine and L-methionine were investigated. Different strains of Saccharomyces cerevisiae were employed in studies of a wide variety of compounds, including acridine, saccharin, salts, tumor promoters and co-carcinogens. Strain D7 was widely employed and antimutagenic activity of spermine, chlorophyllin, cobaltous chloride and fermented milk is reported.
Bronzetti
G
G
Istituto di Mutagenesi e Differenziamento, CNR, Pisa, Italy.
Della Croce
C
C
Galli
A
A
D000818:Animals; D016587:Antimutagenic Agents / Q000494:pharmacology*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D005821:Genetic Techniques; D012441:Saccharomyces cerevisiae / Q000187:drug effects; D012568:Schizosaccharomyces / Q000187:drug effects
D016587:Antimutagenic Agents; D003577:Cytochrome P-450 Enzyme System