title: Adrenocortical blastoma.
abstract: We report a previously undescribed virilizing malignant adrenocortical tumor in an 21-month-old infant with elevated serum alphafetoprotein. The tumor consists of a peculiar mixture of immature epithelial and mesenchymal elements as well as slit-like spaces partially lined by primitive epithelial cells. Focally, the tumor has features reminiscent of the normal embryologic development of the adrenal cortex. A panel of immunohistochemical stains revealed only vimentin reactivity. We propose the term "adrenocortical blastoma" for this unusual neoplasm.
authors.affiliation: Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75235-9072.
authors.forename: K
authors.initials: K
authors.lastname: Molberg
authors.forename: F
authors.initials: F
authors.lastname: Vuitch
authors.forename: D
authors.initials: D
authors.lastname: Stewart
authors.forename: J
authors.initials: J
authors.lastname: Albores-Saavedra
mesh_terms: D000306:Adrenal Cortex Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D008297:Male