Reverse crossed cerebellar diaschisis in partial complex seizures related to herpes simplex encephalitis.
Tc-99m HMPAO brain SPECT was performed in a patient who had partial complex seizures for 1 year after successful acyclovir treatment of biopsy-proven herpes simplex encephalitis 2 years earlier. In spite of antiepileptic medications, her seizures were intractable and occurred daily. Tc-99m HMPAO was administered intravenously while she was having subclinical seizures, and brain SPECT demonstrated an area of hyperperfusion in the right temporal lobe medially and in the contralateral cerebellum. This reverse of the crossed cerebellar diaschisis phenomenon in epileptic disorders has not previously been documented.
Park
C H
CH
Division of Nuclear Medicine, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania 19107.
Kim
S M
SM
Streletz
L J
LJ
Zhang
J
J
Intenzo
C
C
D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging; D002526:Cerebellar Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D004660:Encephalitis / Q000150:complications* / Q000000981:diagnostic imaging; D017029:Epilepsy, Complex Partial / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006561:Herpes Simplex / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime