title: Morphine-induced downregulation of mu-opioid receptors and peptide synthesis in neonatal rat brain.
authors.affiliation: Department of Psychiatry, Hillside Hospital/LIJMC, Glen Oaks, New York 11004.
authors.forename: A
authors.initials: A
authors.lastname: Tempel
authors.forename: K
authors.initials: K
authors.lastname: Espinoza
mesh_terms: D000375:Aging; D000818:Animals; D000831:Animals, Newborn; D015152:Blotting, Northern; D001921:Brain / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D015536:Down-Regulation; D004745:Enkephalins / Q000096:biosynthesis / Q000235:genetics*; D005260:Female; D008431:Maternal-Fetal Exchange; D009020:Morphine / Q000494:pharmacology*; D011247:Pregnancy; D011498:Protein Precursors / Q000096:biosynthesis / Q000235:genetics*; D012313:RNA / Q000302:isolation & purification / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D011957:Receptors, Opioid / Q000187:drug effects / Q000378:metabolism*; D017450:Receptors, Opioid, mu
chemical_list: D004745:Enkephalins; D011498:Protein Precursors; D012333:RNA, Messenger; D011957:Receptors, Opioid; D017450:Receptors, Opioid, mu; C029992:proenkephalin; D012313:RNA; D009020:Morphine