title: Characterisation of a novel repetitive DNA sequence from Mycobacterium bovis.
abstract: We report characterisation of three copies of a novel repeat sequence isolated from a Mycobacterium bovis genomic library. The repeat occurs within open reading frames, potentially encoding a conserved tandem array of a pentapeptide sequence with the consensus X-Gly-Asn-X-Gly. The tandem array is present up to five times in M. bovis and it is proposed that they may occur in a family of genes expressing functionally related proteins. We postulate that these proteins may play a role in binding of M. bovis to host cell receptors.
authors.affiliation: CSIRO Division of Animal Health, Animal Health Research Laboratory, Parkville, Australia.
authors.forename: T J
authors.initials: TJ
authors.lastname: Doran
authors.forename: A L
authors.initials: AL
authors.lastname: Hodgson
authors.forename: J K
authors.initials: JK
authors.lastname: Davies
authors.forename: A J
authors.initials: AJ
authors.lastname: Radford
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D004269:DNA, Bacterial / Q000235:genetics*; D015698:Genomic Library; D008969:Molecular Sequence Data; D009163:Mycobacterium bovis / Q000235:genetics*; D016366:Open Reading Frames; D012091:Repetitive Sequences, Nucleic Acid; D016415:Sequence Alignment
chemical_list: D004269:DNA, Bacterial