title: Local anesthesia: a review.
abstract: Local anesthetics are the most widely administered drugs in dentistry. Significant advances have been made in past decades that have greatly increased both the safety and the efficacy of these important drugs. This paper reviews the history of local anesthesia, pharmacokinetics and clinical implications, techniques, complications, and future directions in the quest for more effective pain control in dentistry.
authors.affiliation: University of Southern California School of Dentistry.
authors.forename: S F
authors.initials: SF
authors.lastname: Malamed
authors.forename: P
authors.initials: P
authors.lastname: Sykes
authors.forename: Y
authors.initials: Y
authors.lastname: Kubota
authors.forename: H
authors.initials: H
authors.lastname: Matsuura
authors.forename: M
authors.initials: M
authors.lastname: Lipp
mesh_terms: D000707:Anaphylaxis / Q000139:chemically induced; D000766:Anesthesia, Dental / Q000009:adverse effects / Q000379:methods; D000779:Anesthetics, Local; D006801:Humans; D009407:Nerve Block / Q000379:methods*; D014662:Vasoconstrictor Agents / Q000009:adverse effects
chemical_list: D000779:Anesthetics, Local; D014662:Vasoconstrictor Agents