title: Use of the holmium:YAG laser in urology.
abstract: The tissue effects of a holmium:YAG (Ho:YAG) laser operating at a wavelength of 2.1 mu with a maximum power of 15 watts (W) and 10 different energy-pulse settings was systematically evaluated on kidney, bladder, prostate, ureteral, and vasal tissue in the dog. In addition, various urologic surgical procedures (partial nephrectomy, transurethral laser incision of the prostate, and laser-assisted vasovasostomy) were performed in the dog, and a laparoscopic pelvic lymph node dissection was carried out in a pig. Although the Ho:YAG laser has a strong affinity for water, precise tissue ablation was achieved in both the contact and non-contact mode when used endoscopically in a fluid medium to ablate prostatic and vesical tissue. Using the usual parameters for tissue destruction (blanching without charring), the depth of thermal injury in the bladder and ureter was kept superficial. In performing partial nephrectomies, a 2-fold reduction in the zone of coagulative necrosis was demonstrated compared to the use of the continuous wave Neodymium:YAG laser (Nd:YAG). When used through the laparoscope, the Ho:YAG laser provided precise cutting and, combined with electrocautery, allowed the dissection to proceed quickly and smoothly. Hemostatic control was adequate in all surgical procedures. Although the results of these investigations are preliminary, our initial experience with the Ho:YAG laser has been favorable and warrants further investigations.
authors.affiliation: Department of Urology, University of Texas M. D. Anderson Cancer Center, Houston 77030.
authors.forename: D E
authors.initials: DE
authors.lastname: Johnson
authors.forename: D M
authors.initials: DM
authors.lastname: Cromeens
authors.forename: R E
authors.initials: RE
authors.lastname: Price
mesh_terms: D000538:Aluminum Silicates; D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure; D003558:Cystoscopy; D003593:Cytoplasm / Q000648:ultrastructure; D004285:Dogs; D006470:Hemorrhage / Q000473:pathology; D006695:Holmium; D007668:Kidney / Q000473:pathology / Q000601:surgery; D007672:Kidney Cortex / Q000473:pathology; D010535:Laparoscopy; D008028:Light Coagulation / Q000295:instrumentation / Q000379:methods; D008197:Lymph Node Excision; D008297:Male; D009336:Necrosis; D010388:Pelvis; D011467:Prostate / Q000473:pathology / Q000601:surgery; D013552:Swine; D013997:Time Factors; D014513:Ureter / Q000473:pathology / Q000601:surgery; D001743:Urinary Bladder / Q000473:pathology / Q000601:surgery; D014551:Urinary Tract / Q000473:pathology / Q000601:surgery*; D014649:Vas Deferens / Q000473:pathology / Q000601:surgery; D015019:Yttrium
chemical_list: D000538:Aluminum Silicates; D015019:Yttrium; D006695:Holmium