Removal of lipoprotein fraction from culture media corrects the reduction of acid sphingomyelinase activity induced by AY9944.
Yoshikawa
H
H
Division of Inherited Metabolic Disorders, National Institute of Neuroscience, Tokyo, Japan.
Sakuragawa
N
N
D000328:Adult; D002460:Cell Line; D002784:Cholesterol / Q000378:metabolism; D003470:Culture Media; D005347:Fibroblasts / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D008074:Lipoproteins; D009542:Niemann-Pick Diseases / Q000378:metabolism*; D013108:Sphingomyelin Phosphodiesterase / Q000037:antagonists & inhibitors*; D001371:trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride / Q000494:pharmacology*
D003470:Culture Media; D008074:Lipoproteins; D001371:trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; D002784:Cholesterol; D013108:Sphingomyelin Phosphodiesterase