title: "Carba" peptide bond surrogates. Different approaches to Gly-psi(CH2-CH2)-D,L-Xaa pseudo-dipeptide units.
abstract: Racemic "carba" pseudo-dipeptide units such as Gly-psi(CH2-CH2)-D,L-Xaa were obtained either through the Horner-Emmons condensation of N-tert.-butyloxycarbonyl-beta alaninal with the appropriate substituted triethyl phosphonacetate, or from commercially available 3-carbethoxy-2-piperidone.
authors.affiliation: CCIPE, Faculty of Pharmacy, Montpellier, France.
authors.forename: M
authors.initials: M
authors.lastname: Rodriguez
authors.forename: A
authors.initials: A
authors.lastname: Heitz
authors.forename: J
authors.initials: J
authors.lastname: Martinez
mesh_terms: D000478:Alkylation; D004151:Dipeptides / Q000138:chemical synthesis / Q000737:chemistry*; D007536:Isomerism; D009557:Nipecotic Acids / Q000737:chemistry; D010746:Phosphonoacetic Acid / Q000031:analogs & derivatives / Q000737:chemistry
chemical_list: D004151:Dipeptides; D009557:Nipecotic Acids; C076890:3-carbethoxy-2-piperidone; C076891:triethyl phosphonoacetate; D010746:Phosphonoacetic Acid