title: Endocarditis with aneurysm involving an aortic homograft used to correct a truncus arteriosus: medical-surgical salvage.
abstract: An aneurysm of an aortic homograft conduit, used to correct a type I truncus arteriosus anomaly in a four month old infant, developed when the patient was 15. Blood cultures grew Staphylococcus aureus. The aneurysm was detected by magnetic resonance imaging and digital subtraction angiocardiography. An emergency open heart operation, guided by these investigations, was performed to remove the original homograft and replace it with another valved aortic homograft. Postoperative antibiotic treatment had to be stopped when profound neutropenia developed. This responded to treatment with recombinant human granulocyte colony stimulating factor. Three years later she was symptom free and did not require medication. Chest x rays and echocardiograms showed a normally functioning heart and conduit valve.
authors.affiliation: Division of Pediatric Cardiology, New York Hospital, Cornell University Medical Center, NY 10021.
authors.forename: M A
authors.initials: MA
authors.lastname: Engle
authors.forename: S J
authors.initials: SJ
authors.lastname: Lang
authors.forename: P
authors.initials: P
authors.lastname: Edelson
mesh_terms: D001014:Aortic Aneurysm / Q000209:etiology*; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D003131:Combined Modality Therapy; D004697:Endocarditis, Bacterial / Q000209:etiology* / Q000628:therapy; D005260:Female; D006801:Humans; D007223:Infant; D016459:Prosthesis-Related Infections / Q000209:etiology* / Q000628:therapy; D013203:Staphylococcal Infections / Q000209:etiology / Q000628:therapy; D014339:Truncus Arteriosus, Persistent / Q000601:surgery*