Management of accidental kerosene ingestion.
Accidental kerosene ingestion is still a common problem in Libya. It causes considerable morbidity and occasionally mortality. The role and choice of antibacterial agents in its management remain unsettled. Pulmonary damage has been reported as resulting from aspiration. In aspiration pneumonia, anaerobic organisms may be important pathogens and metronidazole may have a place in therapy. The present randomized trial in 100 children with accidental kerosene ingestion assesses the role of ampicillin, carbenicillin and metronidazole in its management. The results are not conclusive but chemoprophylaxis appears to decrease morbidity. Of the various regimens used, the ampicillin/metronidazole combination was found to be slightly better than the others. Further study is recommended.
Singh
H
H
Department of Paediatrics, Al Arab Medical University, Benghazi, Libya.
Chugh
J C
JC
Shembesh
A H
AH
Ben-Musa
A A
AA
Mehta
H C
HC
D000059:Accidents; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005334:Fever / Q000139:chemically induced* / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D007648:Kerosene / Q000506:poisoning*; D008297:Male; D012131:Respiratory Insufficiency / Q000139:chemically induced* / Q000188:drug therapy*; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D007648:Kerosene