title: Prevalence of hemoglobinopathies in north Jordan.
abstract: Blood samples from 1,000 subjects, 2-80 years old, were tested to explore the prevalence of alpha-thalassemia trait, high persistent HbF (HPFH), sickle cell trait and beta-thalassemia minor in northern Jordan. Hematological parameters and hemoglobin electrophoresis were carried out on all samples. Results showed 10 (1%) subjects were sickle cell trait, 35 (3.5%) were heterozygous beta thalassemia, 31 (3.1%) alpha thalassemia trait and 10 (1%) high persistent HbF. The prevalence rates were different from those reported in neighbouring countries and their significance is discussed. No other abnormal hemoglobin types were observed.
authors.affiliation: Biochemistry Department, Princess Basma Teaching Hospital, Irbid, Jordan.
authors.forename: N
authors.initials: N
authors.lastname: Bashir
authors.forename: M
authors.initials: M
authors.lastname: Barkawi
authors.forename: L
authors.initials: L
authors.lastname: Sharif
authors.forename: A
authors.initials: A
authors.lastname: Momani
authors.forename: N
authors.initials: N
authors.lastname: Gharaibeh
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001797:Blood Protein Electrophoresis; D002648:Child; D002675:Child, Preschool; D005319:Fetal Hemoglobin; D006580:Genetic Carrier Screening; D006453:Hemoglobinopathies / Q000097:blood / Q000453:epidemiology* / Q000235:genetics; D006801:Humans; D015994:Incidence; D007597:Jordan / Q000453:epidemiology; D008875:Middle Aged; D009313:National Health Programs; D015995:Prevalence
chemical_list: D005319:Fetal Hemoglobin