New glycosphingolipids from the marine sponge Halichondria panicea.
A novel sphingolipid containing an iso-fatty acid, (4E,8E)-N-13'-methyltetradecanoyl-1-O-beta-D-glucopyra nosyl-4-sphingadiene, was isolated from the Oregon marine sponge Halichondria panicea and its structure determined using a combination of spectroscopic and chemical degradation techniques. A second galactosyl-ceramide, which contained an unusually long chain fatty acid amide component, was also isolated from H. panicea.
Nagle
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DG
College of Pharmacy, Oregon State University, Corvallis 97331.
McClatchey
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WC
Gerwick
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WH
D000818:Animals; D006028:Glycosphingolipids / Q000737:chemistry / Q000302:isolation & purification*; D008968:Molecular Conformation; D015394:Molecular Structure; D009904:Optical Rotation; D011161:Porifera / Q000737:chemistry*
D006028:Glycosphingolipids