title: Polyethylene debris-induced osteolysis and loosening in uncemented total hip arthroplasty. A cause of late failure.
abstract: Uncemented total hip arthroplasty has proven to be an acceptable alternative to cemented total hip arthroplasty with good short-term results. With the elimination of the use of polymethyl methacrylate for component fixation, failure at the bone-cement interface, with resultant osteolysis and progressive loosening, was thought to be preventable. Unfortunately the ultra-high-molecular-weight polyethylene acetabular insert can wear and produce particulate debris. This debris can stimulate an osteolytic reaction and lead to late aseptic loosening in a cementless total hip arthroplasty.
authors.affiliation: Department of Orthopaedics, Cleveland Clinic Foundation, OH 44195.
authors.forename: R A
authors.initials: RA
authors.lastname: Cooper
authors.forename: C M
authors.initials: CM
authors.lastname: McAllister
authors.forename: L S
authors.initials: LS
authors.lastname: Borden
authors.forename: T W
authors.initials: TW
authors.lastname: Bauer
mesh_terms: D000077:Acetabulum / Q000473:pathology; D000328:Adult; D002484:Cementation; D006621:Hip Joint / Q000000981:diagnostic imaging / Q000601:surgery; D006622:Hip Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010014:Osteolysis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D011095:Polyethylenes; D011475:Prosthesis Failure; D011859:Radiography; D012086:Reoperation
chemical_list: D011095:Polyethylenes