[Influence of smoking on cholesterol concentrations in serum lipo-protein of healthy subjects].
Sixty hundred and nineteen-seven smokers and 841 non-smokers among healthy male workers of 40-60 years of age were comparatively observed. Their housing environment and working conditions were similar. The results showed that smoking had remarkable influence on the cholesterol concentration in the serum lipo-protein of healthy subjects. The levels of HDL-C HDL2-C, HDL3-C and HDL2-C/HDL3-C of the smoking group were obviously lower than those of the non-smoking group, while the levels of LDL-C, VLDL-C and LDL-C/HDL-C of the smoking group were obviously higher than those of the non-smoking group. Moreover, these indices were significantly associated with the smoking amount, smoking duration, depth of inhalation. Smoking was an important dangerous factor for lowering levels of HDL-C, HDL2-C, HDL 3-C, HDL2-C/HDL3-C and raising levels of LDL-C, VLDL-C, LDL-C/HDL-C. The relative risk (RR) of the two factors were estimated to be 1.09-5.77 and 2.37-3.57 respectively. The levels of the 7 indices such as HDL-C of passive smokers were identical with those of light smokers. This showed that passive smoking also had marked influence on cholesterol concentrations in serum lipoprotein.
Zhang
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Y
Department of Epidemiology, Linyi Medical School, Shandong.
D000328:Adult; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D015243:Cholesterol, VLDL / Q000097:blood; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012907:Smoking / Q000009:adverse effects*; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D015243:Cholesterol, VLDL; D008074:Lipoproteins; D014028:Tobacco Smoke Pollution