Use of immunomodulators (thymopentine) in hepatitis B vaccine in elderly patients undergoing chronic hemodialysis.
Thymopentine is a synthetic immunomodulator that positively affects T-lymphocyte maturation, reproduction and differentiation. In elderly uremic patients nonresponders to hepatitis B vaccine, the administration of this drug has been shown to improve the response to the new vaccination.
Melappioni
M
M
U.O. Nephrology and Dialysis, Istituto Nazionale di Ricerca e Cura Anziani, Ancona, Italy.
Baldassari
M
M
Baldini
S
S
Radicioni
R
R
Panichi
N
N
Saldini
S
S
D000368:Aged; D005260:Female; D006509:Hepatitis B / Q000517:prevention & control; D017325:Hepatitis B Vaccines; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*; D016305:Thymopentin / Q000008:administration & dosage*; D014511:Uremia / Q000276:immunology / Q000628:therapy; D014614:Vaccines, Synthetic / Q000008:administration & dosage; D014761:Viral Hepatitis Vaccines / Q000008:administration & dosage*
D017325:Hepatitis B Vaccines; D014614:Vaccines, Synthetic; D014761:Viral Hepatitis Vaccines; D016305:Thymopentin