[RNA synthesis and transport in the rat liver under the effects of pesticide cotoran (fluometuron)].
The experiments on the investigation of pesticide cotoran-effect on RNA synthesis and transport were carried out. Cotoran was shown to destroy considerably the processes of RNA biosynthesis in rat liver, that results in the decrease of RNA transport from nuclei into cytoplasm. By special experiments it was established that functional activity and the integrity of nuclear membrane (according to the alteration in the activity of nuclear membrane enzyme Mg2-dependent ATP-ase) was not destroyed.
Khamidov
D Kh
DKh
Marakhmedov
A K
AK
Sagatova
G A
GA
Azimova
Sh S
ShS
D000818:Animals; D017301:Ca(2+) Mg(2+)-ATPase / Q000378:metabolism; D002467:Cell Nucleus / Q000378:metabolism; D003593:Cytoplasm / Q000378:metabolism; D006540:Herbicides / Q000494:pharmacology*; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008782:Methylurea Compounds / Q000494:pharmacology*; D009685:Nuclear Envelope / Q000187:drug effects; D012313:RNA / Q000096:biosynthesis* / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar
D006540:Herbicides; D008782:Methylurea Compounds; C005015:fluometuron; D012313:RNA; D017301:Ca(2+) Mg(2+)-ATPase