Effect of plasmid pKM101 in ultraviolet irradiated uvr+ and uvr- Escherichia coli.
The effect of plasmid pKM101 on UV irradiated excision proficient and excision deficient cells was investigated. The plasmid increased the survival of excision proficient cells while partially inhibiting thymine dimer excision. The frequency of mutations was almost unchanged. In excision deficient cells the effect of the plasmid on survival was less pronounced while cell mutability was increased. Our data indicate that the mucAB genes (carried by the plasmid) influence the two types of cells in a different way.
Slezáriková
V
V
Cancer Research Institute, Slovak Academy of Sciences, Bratislava, Czechoslovakia.
Sedliaková
M
M
Andreeva
I V
IV
Rusina OYu
Skavronskaya
A G
AG
D004260:DNA Repair; D004269:DNA, Bacterial / Q000096:biosynthesis / Q000528:radiation effects*; D004926:Escherichia coli / Q000235:genetics* / Q000528:radiation effects; D005798:Genes, Bacterial; D016296:Mutagenesis; D010957:Plasmids; D011740:Pyrimidine Dimers / Q000528:radiation effects; D014466:Ultraviolet Rays
D004269:DNA, Bacterial; D011740:Pyrimidine Dimers