title: Patch test reactions in atopic patients.
abstract: Patch testing was carried out in 851 atopic patients; 181 atopic dermatitis (AD) patients were additionally tested with 50% dilutions of the test substances. The occurrence of allergic and irritant reactions was frequent, being 57% and 33% for AD patients aged 28-41 years and 19-27 years, respectively. Among age-matched allergic rhinitis (AR)/allergic conjunctivitis (AC) or asthma (A) patients, the number of allergic reactions varied from 25 to 30%, and for irritant reactions was 24%. In all groups, nickel, fragrance-mix, balsam of Peru and neomycin were the commonest allergens. Contact allergy to ingredients of topical medicaments was common among AD patients and patients with severe and long-lasting dermatitis were most frequently sensitized. However, sensitivity to multiple substances was not common among those patients. The number of irritant reactions was considerable, but 50% dilution of the test substances did not solve the problem.
authors.affiliation: Department of Dermatology, University of Turku, Finland.
authors.forename: K
authors.initials: K
authors.lastname: Lammintausta
authors.forename: K
authors.initials: K
authors.lastname: Kalimo
authors.forename: V L
authors.initials: VL
authors.lastname: Fagerlund
mesh_terms: D000328:Adult; D000485:Allergens; D003876:Dermatitis, Atopic / Q000150:complications*; D003877:Dermatitis, Contact / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D005189:False Positive Reactions; D006801:Humans; D010328:Patch Tests / Q000379:methods; D015995:Prevalence
chemical_list: D000485:Allergens