Serotonin concentrations in plasma and variations during the menstrual cycle.
We used a specific and sensitive radioenzymatic method to establish a reference interval for the concentration of serotonin in platelet-poor plasma in 98 healthy volunteers (49 men, 49 women). The interval was 0-11 nmol/L with a median of 2.8 nmol/L. No difference in concentration in relation to sex or age was observed. In a group of eight very old volunteers (ages 86-92 years), however, concentrations were increased. In addition, we monitored the plasma concentrations of serotonin in 20 healthy women (ages 26-45 years) through two menstrual cycles. Periovulatory and premenstrual concentrations were greater than the serotonin concentration at the start of menstruation.
Hindberg
I
I
Department of Clinical Chemistry, Frederiksberg Hospital, Denmark.
Naesh
O
O
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008598:Menstruation / Q000502:physiology*; D010060:Ovulation / Q000502:physiology; D012016:Reference Values; D012701:Serotonin / Q000097:blood*
D012701:Serotonin