Anomalous right coronary artery associated with sudden death: an example of a neural crest migration defect.
A unique right coronary artery anomaly of hemodynamic significance was discovered in a young adult who suddenly died. In addition, abnormally migrated, or supernumerary, thymic tissue with embedded parathyroid glands was present. This combination of congenital malformations suggests that the pathogenesis of this rare cardiac anomaly may be explained by a cranial neural crest defect.
Becher
M W
MW
Department of Pathology, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
D000328:Adult; D003330:Coronary Vessel Anomalies / Q000150:complications / Q000175:diagnosis; D003645:Death, Sudden / Q000209:etiology; D005260:Female; D006801:Humans; D009432:Neural Crest / Q000002:abnormalities*