title: [Indications for bone marrow graft in severe hemoglobinopathies].
abstract: Allogenic bone marrow transplantation (ABMT) is the only curative approach for sickle cell anemia and major beta-thalassemia. In sickle cell anemia, ABMT can be proposed for severe clinical disease. In major beta-thalassemia, it must be proposed to young patients who have an HLA identical familial donor.
authors.affiliation: Unité d'Hémato-Oncologie, Hôpital Universitaire des Enfants Reine Fabiola, Bruxelles.
authors.forename: A
authors.initials: A
authors.lastname: Ferster
authors.forename: N
authors.initials: N
authors.lastname: Azzi
authors.forename: W
authors.initials: W
authors.lastname: Bujan
authors.forename: C
authors.initials: C
authors.lastname: Devalck
authors.forename: P
authors.initials: P
authors.lastname: Fondu
authors.forename: S
authors.initials: S
authors.lastname: Nafa
authors.forename: M
authors.initials: M
authors.lastname: Toppet
authors.forename: E
authors.initials: E
authors.lastname: Sariban
mesh_terms: D000755:Anemia, Sickle Cell / Q000097:blood / Q000628:therapy*; D016026:Bone Marrow Transplantation; D005319:Fetal Hemoglobin; D006801:Humans; D013789:Thalassemia / Q000628:therapy*; D014019:Tissue Donors; D014184:Transplantation, Homologous
chemical_list: D005319:Fetal Hemoglobin