title: Failure of vaccination against hepatitis B with Gen H-B-Vax-D in immunosuppressed heart transplant recipients.
abstract: Some 86 heart transplant recipients under immunosuppressive therapy were vaccinated against hepatitis B using the vaccine Gen H-B-Vax-D, but 95.3% failed to develop protective levels of HBs-specific antibody (more than 10 U/l) after the third vaccination.
authors.affiliation: Institut für Virologie und Seuchenhygiene, Medizinische Hochschule Hannover.
authors.forename: D
authors.initials: D
authors.lastname: Wagner
authors.forename: I
authors.initials: I
authors.lastname: Wagenbreth
authors.forename: R
authors.initials: R
authors.lastname: Stachan-Kunstyr
authors.forename: J
authors.initials: J
authors.lastname: Flik
mesh_terms: D005260:Female; D016027:Heart Transplantation; D006509:Hepatitis B / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D017325:Hepatitis B Vaccines; D006801:Humans; D016867:Immunocompromised Host; D007165:Immunosuppression Therapy / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D065227:Transfusion Reaction; D014611:Vaccination
chemical_list: D017325:Hepatitis B Vaccines