Is there a role for gamma delta T cells in malaria?
Peripheral blood lymphocytes of the V gamma 9+ family of gamma delta T cells proliferate vigorously in response to Plasmodium falciparum. In this brief article, Jean Langhorne and colleagues discuss this response and assess the possible role of gamma delta T cells in the pathogenesis of malaria.
Langhorne
J
J
Max-Planck-Institut für Immunbiologie, Freiburg, FRG.
Goodier
M
M
Behr
C
C
Dubois
P
P
D000818:Animals; D000953:Antigens, Protozoan / Q000276:immunology; D006224:Cricetinae; D008213:Lymphocyte Activation / Q000276:immunology; D016778:Malaria, Falciparum / Q000276:immunology*; D010963:Plasmodium falciparum / Q000276:immunology; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
D000953:Antigens, Protozoan; D016692:Receptors, Antigen, T-Cell, gamma-delta