title: [Molecular basis of regulation of contraction of skeletal muscle cells and the role of calcium. Mathematical modeling].
abstract: The review summarizes recent knowledge concerning regulatory mechanisms of skeletal muscle cell contraction. Calcium ions are the essential mediator of these processes. Their primary function is signal transmission from the sarcoplasmic reticulum to contractile proteins. A large variety of methods is available for the investigation of such complex molecular processes, ranging from physiological through biochemical and morphological to biophysical and mathematical approaches. Mathematical modelling is assessed comprehensively in the last part of the review. (Fig. 3, Ref. 58.)
authors.affiliation: Ustav molekulárnej fyziológie a genetiky SAV, Bratislava, CSFR.
authors.forename: M
authors.initials: M
authors.lastname: Hollý
authors.forename: J
authors.initials: J
authors.lastname: Poledna
mesh_terms: D000818:Animals; D002118:Calcium / Q000502:physiology*; D006801:Humans; D008954:Models, Biological; D009119:Muscle Contraction / Q000502:physiology*
chemical_list: D002118:Calcium