[Indications for bone marrow graft in severe hemoglobinopathies].
Allogenic bone marrow transplantation (ABMT) is the only curative approach for sickle cell anemia and major beta-thalassemia. In sickle cell anemia, ABMT can be proposed for severe clinical disease. In major beta-thalassemia, it must be proposed to young patients who have an HLA identical familial donor.
Ferster
A
A
Unité d'Hémato-Oncologie, Hôpital Universitaire des Enfants Reine Fabiola, Bruxelles.
Azzi
N
N
Bujan
W
W
Devalck
C
C
Fondu
P
P
Nafa
S
S
Toppet
M
M
Sariban
E
E
D000755:Anemia, Sickle Cell / Q000097:blood / Q000628:therapy*; D016026:Bone Marrow Transplantation; D005319:Fetal Hemoglobin; D006801:Humans; D013789:Thalassemia / Q000628:therapy*; D014019:Tissue Donors; D014184:Transplantation, Homologous
D005319:Fetal Hemoglobin