Human liver glutamic gamma-semialdehyde dehydrogenase: structural relationship to the yeast enzyme.
The amino acid sequences of nine tryptic peptides (containing altogether 105 amino acids) from human liver glutamic gamma-semialdehyde of dehydrogenase (hitherto designated as ALDH4) were found to correspond, at 33-66% identity, to segments from the yeast 1-proline-5-carboxylate (P5C) dehydrogenase encoded by the PUT2 gene.
Hempel
J
J
Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, PA 15261.
Eckey
R
R
Berie
D
D
Romovacek
H
H
Agarwal
D P
DP
Goedde
H W
HW
D050842:1-Pyrroline-5-Carboxylate Dehydrogenase; D000595:Amino Acid Sequence; D006801:Humans; D008099:Liver / Q000201:enzymology*; D008969:Molecular Sequence Data; D000587:Oxidoreductases Acting on CH-NH Group Donors / Q000737:chemistry*; D010455:Peptides / Q000032:analysis; D012441:Saccharomyces cerevisiae / Q000201:enzymology*; D029701:Saccharomyces cerevisiae Proteins; D017385:Sequence Homology
D010455:Peptides; D029701:Saccharomyces cerevisiae Proteins; D050842:1-Pyrroline-5-Carboxylate Dehydrogenase; C494240:ALDH4A1 protein, human; C494242:PUT2 protein, S cerevisiae; D000587:Oxidoreductases Acting on CH-NH Group Donors