title: Malaria: becoming more specific about non-specific immunity.
abstract: For the hundreds of millions of people presently infected with malaria, survival may depend on relatively non-specific immune effector mechanisms. Progress has been made in understanding the anti-parasitic properties of tumor necrosis factor-alpha, interferon-gamma and nitric oxide, in defining the parasite toxins that induce tumor necrosis factor-alpha production, and in exploring the role of cytokines and adhesion molecules in the pathogenesis of cerebral malaria.
authors.affiliation: Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK.
authors.forename: D
authors.initials: D
authors.lastname: Kwiatkowski
mesh_terms: D000818:Animals; D004912:Erythrocytes / Q000469:parasitology; D006790:Host-Parasite Interactions; D006801:Humans; D007109:Immunity; D008099:Liver / Q000469:parasitology; D008288:Malaria / Q000276:immunology*; D016779:Malaria, Cerebral / Q000276:immunology; D016778:Malaria, Falciparum / Q000276:immunology; D010963:Plasmodium falciparum / Q000276:immunology; D016052:Protozoan Vaccines / Q000276:immunology; D014409:Tumor Necrosis Factor-alpha / Q000096:biosynthesis
chemical_list: D016052:Protozoan Vaccines; D014409:Tumor Necrosis Factor-alpha