[Severe hepatitis with encephalopathy induced by acetylsalicylic acid in a case of lupus erythematosus disseminatus].
The observation of a 62 year-old woman who had been suffering from arthritis for several years and in whom treatment with high doses of acetylsalicylic acid resulted in severe acute hepatitis is reported. Clinical and serological findings led to the diagnosis of systemic lupus erythematosus complicated by acute drug induced hepatitis.
De Leeuw
P
P
Service de Gastroentérologie, Cliniques Universitaires St-Luc, Bruxelles, Belgique.
Lefebvre
C
C
Tomasi
J P
JP
Rahier
J
J
Geubel
A
A
D001241:Aspirin / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D005260:Female; D006501:Hepatic Encephalopathy / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy*; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use
D011239:Prednisolone; D001241:Aspirin