title: Juvenile hemangiomas involving the thoracic trachea in children: report of two cases.
abstract: Two 3-month-old girls presented with posterior mediastinal juvenile hemangioma (JH), a benign tumor rarely found in the mediastinum. Incomplete resections were performed. Over 4 and 7 months, respectively, the hemangiomas recurred and grew through the tracheal wall into the tracheal lumina, reducing the airway by 90% in one case and 70% in the other. The recurrences were resected, including five tracheal rings in the first case and four in the second. In case 1 the tumor recurred in the trachea 2 months later. A tracheostomy was performed, and corticosteroids were administered for 6 months. The tumor involuted and the patient was decannulated after 18 months; she is doing well 7 years later. The patient in case 2 has been well in the 18 months since her second operation. Airway obstructions can be treated by tracheal resection when conservative management fails.
authors.affiliation: Department of Surgery, Hospital for Sick Children, Toronto, Ontario, Canada.
authors.forename: A
authors.initials: A
authors.lastname: Messineo
authors.forename: D E
authors.initials: DE
authors.lastname: Wesson
authors.forename: R M
authors.initials: RM
authors.lastname: Filler
authors.forename: C R
authors.initials: CR
authors.lastname: Smith
mesh_terms: D000402:Airway Obstruction / Q000473:pathology / Q000601:surgery; D001999:Bronchoscopy; D003131:Combined Modality Therapy; D005260:Female; D006390:Hemangioendothelioma / Q000151:congenital* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007223:Infant; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery; D011241:Prednisone / Q000008:administration & dosage; D014132:Trachea / Q000473:pathology; D014134:Tracheal Neoplasms / Q000151:congenital* / Q000473:pathology / Q000601:surgery; D014139:Tracheostomy
chemical_list: D011241:Prednisone