[Gastric emptying of solids, acid secretion and tobacco in duodenal ulcer].
We study in a group of patients with endoscopically diagnosed duodenal ulcer (19; 17 males) and controls (11; 7 males) the gastric emptying of solids through scintigraphy and gastric acid secretion by standard tests. In the same way we investigated prospectively some clinical data, specially smoking habits. As a whole, patients with duodenal ulcer showed an emptying of solids slightly faster than controls (T 1/2-minutes-: 85.4 +/- 28.6 in patients with duodenal ulcer versus 116.9 +/- 46.5 in controls, p less than 0.03). However, most of our patients (15 of 19 or 79%) were found to have a normal emptying rate. No correlation was found between secretory outputs and gastric emptying. Smokers with duodenal ulcer had a faster emptying that non-smokers with duodenal ulcer (T 1/2 74.8 +/- 30.05 vs. 99.91 +/- 19.86; p = 0.05).
Montoro
M
M
Servicio de Aparato Digestivo y Medicina Nuclear, Hospital Clínico Universitario, Zaragoza.
Gomollón
F
F
Sopeña
F
F
Prats
E
E
Banzo
J
J
Gomollón
J P
JP
López Zaborras
J
J
Lanas
A
A
Sáinz
R
R
D000328:Adult; D004381:Duodenal Ulcer / Q000378:metabolism / Q000503:physiopathology*; D005744:Gastric Acid / Q000378:metabolism*; D005746:Gastric Emptying; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012907:Smoking / Q000378:metabolism / Q000503:physiopathology*