[Influences of naomaitong upon cerebral blood flow in dogs].
This experiment has proven that the drug naomaitong can synchronously increase the blood flow of both dog's internal carotid artery and vertebral artery and also can antagonize the decrease of blood flow of both arteries caused by pituitrin. The increase of blood flow of both internal carotid artery and vertebral artery due to administration of naomaitong (1.2 g/kg) through the dog's duodenum is approximately equal to the increase of blood flow of both arteries resulting from the intramuscular injection of papaverine (1 mg/kg). Besides, the dosage of naomaitong is positively correlated to the effect and action of the drug.
He
G
G
Institute of Chinese Materia Medica, Hubei College of Traditional Chinese Medicine, Wuhan.
Chen
X
X
Chang
L
L
Liu
J
J
Ye
S
S
Yang
J
J
D000818:Animals; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D010208:Papaverine / Q000494:pharmacology; D010909:Pituitary Hormones, Posterior / Q000037:antagonists & inhibitors
D004365:Drugs, Chinese Herbal; D010909:Pituitary Hormones, Posterior; D010208:Papaverine