[A new method of a morphometric study of the kidney using a computer-assisted morphometric complex "Diamorph"].
The use of a computer--based morphometric complex "DIAMORPH" for automated morphometric analysis of renal glomeruli is described. By combining the principles of morphological and functional approaches to diagnosis with the capabilities of present--day research equipment, a new informative morphometric parameter--the extent of capillary--mesangium contact--has been identified. With this parameter and its derivatives, it has been possible to differentiate, in a statistically significant way (p less than 0.01), healthy subjects (controls) from patients with manifest diabetes mellitus of up to I year in duration who could not be distinguished through light microscopic or conventional morphometric studies.
Zhukotskiĭ
A V
AV
Iakubova
N I
NI
Ponomarev
A B
AB
Purtov
B A
BA
Pal'tsev
M A
MA
Kogan
E M
EM
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D003928:Diabetic Nephropathies / Q000175:diagnosis* / Q000473:pathology; D003936:Diagnosis, Computer-Assisted; D005260:Female; D006801:Humans; D007668:Kidney / Q000033:anatomy & histology* / Q000473:pathology; D007678:Kidney Glomerulus / Q000033:anatomy & histology / Q000473:pathology; D008297:Male; D008838:Microcomputers; D008875:Middle Aged