title: [Cytogenetics of unfertilized or uncleaved oocytes within the scope of in vitro fertilization. Relations to hormone content of follicular fluid].
abstract: Constituents of the follicular fluid (FF) have been suspected to influence fertilizability and cytogenetic constitution of human oocytes. Therefore, we analysed the FF concentrations of 17 beta-estradiol (E2), progesterone (P), testosterone (T), and prolactin (PRL) of 114 oocytes recovered for in vitro fertilisation (IVF). 46 of these oocytes were fertilised and transferred to the maternal uterus. Among the unfertilized gametes, 27 were not analysable. 30 were normal haploid, and 11 were classified as abnormal. There was no significant difference between fertilised and unfertilized oocytes for FF concentrations of E2, P, T, and PRL and for the E2/P ratios. Similarly, we detected no significant difference between normal and abnormal oocytes for these parameters.
authors.affiliation: Abteilung Frauenheilkunde und Geburtshilfe, Universität Ulm.
authors.forename: B
authors.initials: B
authors.lastname: Rosenbusch
authors.forename: K
authors.initials: K
authors.lastname: Sterzik
authors.forename: C
authors.initials: C
authors.lastname: Lauritzen
mesh_terms: D002869:Chromosome Aberrations / Q000235:genetics*; D002970:Cleavage Stage, Ovum / Q000502:physiology*; D005260:Female; D005306:Fertilization / Q000235:genetics* / Q000502:physiology; D005307:Fertilization in Vitro; D015571:Follicular Fluid / Q000502:physiology*; D012739:Gonadal Steroid Hormones / Q000502:physiology*; D006801:Humans; D007621:Karyotyping
chemical_list: D012739:Gonadal Steroid Hormones