title: Laryngotracheobronchitis as a complication of measles during an urban epidemic.
abstract: OBJECTIVE
  To evaluate demographic and clinical correlates of laryngotracheobronchitis (LTB) as a complication of measles during a community-wide epidemic.
  
  
  METHODS
  Retrospective review of medical records.
  
  
  METHODS
  Childrens Hospital Los Angeles, a large urban pediatric facility, during a regional epidemic of measles studied January through June 1990.
  
  
  METHODS
  All patients identified at our hospital who met Centers for Disease Control criteria for measles.
  
  
  RESULTS
  Of 440 patients with measles, 82 also had LTB (18.6%). Patients in whom LTB developed were significantly younger (mean +/- SD: 14.7 +/- 8.2 months) than the cohort (24.8 +/- 30.1 months) (p less than 0.001) and more likely to require hospitalization (91.5%) than the cohort (44.3%) (p less than 0.001). Thirteen patients (17.3%) required intensive care, including 9 (11%) who required endotracheal intubation for a mean of 8.3 +/- 7.1 days. Pulmonary function testing of five patients with an endotracheal tube in place, including three not clinically assessed as having pneumonia, indicated the presence of concomitant lower respiratory tract disease.
  
  
  CONCLUSIONS
  Laryngotracheobronchitis was a frequent and often severe complication of measles. The likelihood that LTB would develop was inversely related to age, generally required inpatient care, and necessitated endotracheal intubation in severely affected patients.
authors.affiliation: Childrens Hospital Los Angeles, Division of Infectious Diseases, CA 90027.
authors.forename: L A
authors.initials: LA
authors.lastname: Ross
authors.forename: W H
authors.initials: WH
authors.lastname: Mason
authors.forename: J
authors.initials: J
authors.lastname: Lanson
authors.forename: T W
authors.initials: TW
authors.lastname: Deakers
authors.forename: C J
authors.initials: CJ
authors.lastname: Newth
mesh_terms: D000293:Adolescent; D000328:Adult; D001991:Bronchitis / Q000453:epidemiology / Q000209:etiology*; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D007223:Infant; D007827:Laryngitis / Q000453:epidemiology / Q000209:etiology*; D015141:Los Angeles; D008297:Male; D008457:Measles / Q000150:complications* / Q000453:epidemiology; D012189:Retrospective Studies; D014136:Tracheitis / Q000453:epidemiology / Q000209:etiology*; D014504:Urban Health