[Synergic effect of Dextran 70 at 32% and an antibiotic in the prevention of peritoneal adhesions. Experimental study in rats].
In an experimental study we evaluate the anti-adherential effect of four different solutions: physiological serum, Chloramphenicol, Dextran 70 (32%) and the association of these last two solutions. Synergic effect is shown when using an antibiotic (Chloramphenicol) with a non-bactericid solution (Dextran). Comparing our results with current literature, we are confident on the efficacity of similar association concerning other solutions than Dextran 70 (32%).
Boudouris
O
O
Service de Chirurgie, Hôpital Pierre Rouqués, Paris.
Autret
M
M
Paris
F X
FX
Karaïtianos
I
I
Loisance
D
D
Henry-Suchet
J
J
D000818:Animals; D002429:Cecal Diseases / Q000517:prevention & control*; D002701:Chloramphenicol / Q000627:therapeutic use*; D003911:Dextrans / Q000627:therapeutic use*; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005260:Female; D010532:Peritoneal Diseases / Q000517:prevention & control*; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values; D000267:Tissue Adhesions / Q000517:prevention & control
D003911:Dextrans; D002701:Chloramphenicol