title: Chronic Pneumocystis carinii infection of the liver. A case report and review of the literature.
abstract: Pneumocystis carinii infection of the liver is being reported with increasing frequency in patients with acquired immune deficiency syndrome (AIDS). The clinical picture typically resembles hepatitis. We report such an occurrence in a patient with persistent elevation of alkaline phosphatase and gamma-glutamyl transpeptidase with relatively normal transaminases who was found to have P. carinii on antemortem liver biopsy. The differential diagnosis of abnormal alkaline phosphatase and gamma-glutamyl transpeptidase in patients with AIDS should include P. carinii.
authors.affiliation: Department of Medicine, University of Piitsburgh School of Medicine, Pennsylvania.
authors.forename: I S
authors.initials: IS
authors.lastname: Merkel
authors.forename: C B
authors.initials: CB
authors.lastname: Good
authors.forename: M
authors.initials: M
authors.lastname: Nalesnik
authors.forename: S R
authors.initials: SR
authors.lastname: Roseman
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000469:Alkaline Phosphatase / Q000378:metabolism; D002908:Chronic Disease; D004789:Enzyme Activation / Q000502:physiology; D006505:Hepatitis / Q000201:enzymology / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008099:Liver / Q000201:enzymology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000201:enzymology / Q000473:pathology; D016720:Pneumocystis Infections / Q000201:enzymology / Q000209:etiology* / Q000473:pathology; D013194:Staining and Labeling; D005723:gamma-Glutamyltransferase / Q000378:metabolism
chemical_list: D005723:gamma-Glutamyltransferase; D000469:Alkaline Phosphatase