[Nephrotic syndrome associated with AIDS in children].
Several renal and renal-related disturbances have been described in patients with AIDS (acquired immune deficiency syndrome), in adults and children as well. These are mainly electrolyte and acid-base imbalance, acute renal failure and nephrotic syndrome. The latter is usually steroid non-responder. The renal histopathological lesions described more commonly are minimal change, mesangial hyperplasia and focal segmental glomerulosclerosis. Herein, we describe a 5 year-old with AIDS, that developed nephrotic syndrome, characterized by edema, ascites, hypoalbuminemia and massive proteinuria. A percutaneous renal biopsy showed mesangial proliferation. She did not respond to a 6 week treatment with prednisone. She died with sepsis after several viral and bacterial infections.
Muñoz-Arizpe
R
R
Departamento de Nefrología, Hospital Infantil de México Federico Gómez, México, D.F.
Romero-Navarro
B
B
Gómez-Chico
R
R
Velásquez-Jones
L
L
Samudio-Domínguez
G
G
Ramón-García
G
G
Valencia-Mayoral
P
P
D016263:AIDS-Associated Nephropathy; D002675:Child, Preschool; D005260:Female; D006801:Humans; D009404:Nephrotic Syndrome