Sequential and combined G-banding for identifying breakpoints in sister chromatid exchanges.
A simple new method is described for obtaining sequential and a combination of differential sister chromatid staining and G-banding in the same metaphase. Using this method the sister chromatid exchanges and chromosome lesion breakpoints can be precisely localized in particular bands of individual chromosomes.
Fuster
C
C
Department of Cell Biology and Physiology, Subunit of Biology, Faculty of Medicine, University of Barcelona, Spain.
Miró
R
R
Barrios
L
L
Egozcue
J
J
D002871:Chromosome Banding / Q000379:methods*; D002873:Chromosome Fragility; D006801:Humans; D008677:Metaphase / Q000502:physiology; D012854:Sister Chromatid Exchange / Q000502:physiology*; D013194:Staining and Labeling / Q000379:methods