Description of the deformation of the left ventricle by a kinematic model.
A model of left ventricular (LV) kinematics is essential to identify the fundamental physiological modes of LV deformation during a complete cardiac cycle as observed from the motion of a finite number of markers embedded in the LV wall. Kinematics can be described by a number of modes of motion and deformation in succession. An obvious mode of LV deformation is the ejection of cavity volume while the wall thickens. In the more sophisticated model of LV kinematics developed here, seven time-dependent parameters were used to describe not only volume change but also torsion and shape changes throughout the cardiac cycle. Rigid-body motion required another six parameters. The kinematic model employed a deformation field that had no singularities within the myocardium, and all parameters describing the modes of deformation were dimensionless. Note that torsion, volume and symmetric shape changes all require the definition of a cardiac coordinate system, which has generally been related to the measured cardiac geometry by reference to approximate anatomical landmarks. However, in the present study the coordinate system was positioned objectively by a least-squares fit of the kinematic model to the measured motion of markers. Theoretically, at least five markers are needed to find a unique set of parameters.(ABSTRACT TRUNCATED AT 250 WORDS)
Arts
T
T
Cardiovascular Research Institute Maastricht, University of Limburg, The Netherlands.
Hunter
W C
WC
Douglas
A
A
Muijtjens
A M
AM
Reneman
R S
RS
D000818:Animals; D015415:Biomarkers; D003198:Computer Simulation; D003287:Contrast Media; D003971:Diastole / Q000502:physiology; D004285:Dogs; D008955:Models, Cardiovascular; D009200:Myocardial Contraction / Q000502:physiology*; D013599:Systole / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology*
D015415:Biomarkers; D003287:Contrast Media