[Late pulmonary changes following bleomycin administration in computed tomography. Nodular fibrosis mimicking a seminoma metastasis].
This is a case report of a patient with multiple metastases to the lung due to a seminoma, treated with a chemotherapeutic regimen containing bleomycin. The typical subpleural fibrosis of the lung related to bleomycin damage disappeared 6 months after the start of chemotherapy. 4 weeks later, a solitary nodule at a prior unchanged site of the lung appeared, mimicking recurrent metastasis. Explorative thoracotomy revealed a nodular fibrosis of the lung, representing a late reaction of the lung to chemotherapy damage.
Gehl
H B
HB
Klinik für Radiologische Diagnostik, RWTH Aachen.
Hauptmann
S
S
Sohn
M
M
Bohndorf
K
K
D000328:Adult; D001761:Bleomycin / Q000009:adverse effects*; D003937:Diagnosis, Differential; D004407:Dysgerminoma / Q000188:drug therapy / Q000556:secondary*; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary*; D008297:Male; D011658:Pulmonary Fibrosis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D013736:Testicular Neoplasms / Q000188:drug therapy* / Q000473:pathology; D013997:Time Factors; D014057:Tomography, X-Ray Computed
D001761:Bleomycin