DNA analysis of two patients with a non-fluorescent Y chromosome.
Results of DNA study on two patients of gonadal dysgenesis with a 45,X/46,X,Ynf (non-fluorescent Y chromosome) karyotype are described. In one patient who developed gonadoblastoma, all 12 loci on the non-fluorescent part of Yq were detected. Another patient did not have gonadoblastoma at 20 years, and only the proximal 6 loci out of 12 were detected.
Sekine
T
T
Department of Pediatrics, Tokyo University Hospital, Japan.
Fukutani
K
K
Motegi
T
T
Hayakawa
H
H
Tamura
T
T
Nagafuchi
S
S
Nakahori
Y
Y
Nakagome
Y
Y
D000328:Adult; D002648:Child; D002871:Chromosome Banding; D015342:DNA Probes; D004407:Dysgerminoma / Q000235:genetics; D005260:Female; D005453:Fluorescence; D005833:Genital Neoplasms, Female / Q000235:genetics; D006059:Gonadal Dysgenesis / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D014998:Y Chromosome
D015342:DNA Probes