title: [Liver diseases in children with alpha 1-antitrypsin deficiency in infancy].
abstract: The authors evaluate the health status of children with alpha-1-antitrypsin deficiency, focused on liver disease in infant age. The children were selected by neonatal screening. Of 21 children one had severe neonatal hepatitis with progression to cirrhosis, 2 children had clinically apparent jaundice to the age of two months, 6 children had elevated total bilirubin and transaminase levels without clinical signs of the disease, 12 of the remaining children had no clinical and laboratory signs of liver disease. In the discussion the authors compare the results with data published abroad.
authors.affiliation: Výzkumný ústav zdraví dítĕte, Brno.
authors.forename: M
authors.initials: M
authors.lastname: Durpektová
authors.forename: J
authors.initials: J
authors.lastname: Kamarýt
authors.forename: A
authors.initials: A
authors.lastname: Pijácková
authors.forename: R
authors.initials: R
authors.lastname: Rysavý
authors.forename: K
authors.initials: K
authors.lastname: Husek
mesh_terms: D005260:Female; D006801:Humans; D007223:Infant; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000201:enzymology* / Q000473:pathology; D008297:Male; D019896:alpha 1-Antitrypsin Deficiency