[Changes and significance of chemiluminescence of polymorphonuclear leukocytes in endotoxin-induced lung injury in conscious sheep].
The chemiluminescence (CL) of polymorphonuclear leukocytes and its relation with pulmonary microvascular permeability after endotoxin-induced lung injury in conscious sheep with lung lymph fistula were observed. Four hours after the injury the CL of PMNs increased from 0.27 cpm/PMN of baseline to 0.69 cpm/PMN (P < 0.05). The increment of the CL had positive correlation with the increment of lung lymph flow or permeability index (r = 0.632 0.638 P < 0.05), suggesting that the increase of pulmonary microvascular permeability after the endotoxin injury had relation with the increase of the respiratory tract of PMNs.
Chen
J K
JK
Department of Respiratory Disease, XiJing Hospital, 4th Millitary Medical College.
D000818:Animals; D002199:Capillary Permeability; D004731:Endotoxins; D004926:Escherichia coli; D005260:Female; D007958:Leukocyte Count; D008163:Luminescent Measurements; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000139:chemically induced / Q000473:pathology* / Q000503:physiopathology; D009504:Neutrophils / Q000502:physiology*; D012756:Sheep
D004731:Endotoxins