title: Neuropeptide Y-like immunoreactivity in the dogfish gastroenteropancreatic tract: light and electron microscopical study.
abstract: The 36 amino acid neuropeptide Y (NPY) has been examined in mammals and is mainly located in the nerves. Its distribution in nonmammalian vertebrate and in some invertebrate nervous systems has been confirmed. Using antisera raised to porcine NPY, NPY immunoreactivity has been localized in endocrine cells of the pancreas and gastrointestinal tract of two dogfish, Scyliorhinus stellaris and Scyliorhinus canicula. Immunostained serial sections and cross-absorption experiments with related peptides, including avian and bovine pancreatic polypeptide and peptide tyrosine tyrosine, excluded any cross-reactivity. The fine structure of the cells containing NPY-like substance is described.
authors.affiliation: Institute of Human Anatomy, 2nd Medical School, University of Naples, Federico II.
authors.forename: V
authors.initials: V
authors.lastname: Cimini
authors.forename: S
authors.initials: S
authors.lastname: van Noorden
authors.forename: M
authors.initials: M
authors.lastname: Sansone
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D004064:Digestive System / Q000201:enzymology / Q000378:metabolism* / Q000648:ultrastructure; D004284:Dogfish / Q000378:metabolism*; D005260:Female; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D008969:Molecular Sequence Data; D009478:Neuropeptide Y / Q000378:metabolism*; D010179:Pancreas / Q000201:enzymology / Q000378:metabolism* / Q000648:ultrastructure
chemical_list: D009478:Neuropeptide Y