Dowling-Degos' disease mimicking chloracne.
We describe a patient with clinical features that resembled severe chloracne; however, histopathologic findings revealed a reticulated pigmented anomaly. Innumerable comedones, many cysts, acneiform scarring, and flexural and facial pigmentation were noted in this patient, who is a machinist. A serum test for polychlorinated biphenyl was negative, which eliminated a diagnosis of chloracne. The spectrum of clinical features of the histologically well-defined Dowling-Degos' disease is discussed; in this disease lesions can be flexural or acral and can appear as macules, comedones, or cysts.
Kershenovich
J
J
Department of Dermatology, University of California, San Francisco 94143.
Langenberg
A
A
Odom
R B
RB
LeBoit
P E
PE
D000152:Acne Vulgaris / Q000139:chemically induced / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D010859:Pigmentation Disorders / Q000473:pathology*; D011078:Polychlorinated Biphenyls / Q000009:adverse effects
D011078:Polychlorinated Biphenyls