title: Frequency and output-dependent change in conduction over slow pathways in a patient with sustained ventricular tachycardia unrelated to coronary artery disease.
abstract: In a patient with sustained ventricular tachycardia, we obtained two different paced QRS morphologies from a single pacing site. In one QRS morphology the stimulus to the QRS complex was long, 150 msec, and in the other it was 100 msec. At the paced cycle length of 600 msec and the stimulus output of 4 V, one QRS morphology with the stimulus to the onset of QRS activation (St-QRS) interval of 150 msec was observed. At the paced cycle length of 400 msec, the other QRS morphology with a St-QRS interval of 100 msec was observed alternatively with the former. At the paced cycle length of 353 msec or 316 msec, the latter with a shorter St-QRS interval was exclusively observed. When the stimulus output was increased from 4 to 10 V, keeping with the paced cycle length at 400 msec, the St-QRS interval was shortened from 100 to 80 msec. For the two QRS morphologies with two St-QRS intervals, two slowly conducting pathways would be responsible. The site of the block in the faster pathway must be located at the proximity of the pacing site and the conduction at a shorter paced cycle length would be explained by "supernormal conduction."
authors.affiliation: First Department of Internal Medicine, Niigata University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Chinushi
authors.forename: Y
authors.initials: Y
authors.lastname: Aizawa
authors.forename: T
authors.initials: T
authors.lastname: Funazaki
authors.forename: M
authors.initials: M
authors.lastname: Tamura
authors.forename: A
authors.initials: A
authors.lastname: Shibata
mesh_terms: D002037:Bundle-Branch Block / Q000175:diagnosis; D002304:Cardiac Pacing, Artificial; D003327:Coronary Disease / Q000175:diagnosis; D004562:Electrocardiography; D004594:Electrophysiology; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013610:Tachycardia / Q000175:diagnosis / Q000503:physiopathology*