title: Rationale for and work of the Perinatal Trials Service.
abstract: The Perinatal Trials Service provides a service to busy clinicians who wish to mount large simple-in-design randomized trials. The trials aim to identify moderate, but clinically useful, effects of promising treatments for the most important problems in perinatal care. A combination of a flexible five-person core resource and a cadre of staff employed to work on specific trials allows a programme of trials to be conducted successfully and efficiently. The Perinatal Trials Service has three main areas of work: prevention and treatment of immaturity and its consequent morbidity; identification and management of the compromised fetus or baby; and prevention and treatment of maternal morbidity. Examples of projects from each area are described.
authors.affiliation: Perinatal Trials Service, Radcliffe Infirmary, Oxford, UK.
authors.forename: A
authors.initials: A
authors.lastname: Grant
mesh_terms: D010500:Perinatology; D016032:Randomized Controlled Trials as Topic / Q000592:standards; D012107:Research Design / Q000592:standards; D013673:Technology Assessment, Biomedical