Evidence for a hydroxy-aluminium polymer (Al13) in synaptosomes.
The presence of the hydroxy-aluminium polymer (Al13-(OH)24O4(H2O)12(7+)) was noticed inside synaptosomes when synaptosomes were incubated with Al(NO3)3 at neutral pH values. Dysprosium nitrate (Dy(NO3)3)--a shift reagent--facilities the identification of the Al13 species distinctly inside the synaptosomes. 27Al NMR was used as a tool to detect the Al13 complex inside and outside the synaptosomes.
Rao
G V
GV
Department of Nutrition and Food Safety, Central Food Technological Research Institute, Mysore, India.
Rao
K S
KS
D000535:Aluminum / Q000378:metabolism*; D000536:Aluminum Hydroxide / Q000032:analysis; D000818:Animals; D004419:Dysprosium; D006863:Hydrogen-Ion Concentration; D009682:Magnetic Resonance Spectroscopy; D009566:Nitrates; D011108:Polymers / Q000032:analysis; D051381:Rats; D017208:Rats, Wistar; D013574:Synaptosomes / Q000737:chemistry*
D009566:Nitrates; D011108:Polymers; C077424:dysprosium nitrate; C077423:hydroxy-aluminum polymer; D004419:Dysprosium; D000536:Aluminum Hydroxide; D000535:Aluminum