The effect of barium selenate injection on selenium concentration and glutathione peroxidase activity in blood of pregnant ewes fed selenium-deficient diet.
Selenium (Se) levels in whole blood and plasma, and glutathione peroxidase (GSH-Px) activities in red cells and plasma were measured in ewes fed an Se-deficient diet injected with barium selenate before breeding season. Highly significant increases in Se levels and GSH-Px activities (P less than 0.001) were observed throughout the gestation period and during lactation. In the control group, Se levels and GSH-Px activities decreased significantly (P less than 0.001), and were at critically low levels during lambing and lactation periods.
Zachara
B A
BA
Department of Biochemistry, Medical School, Bydgoszcz, Poland.
Trafikowska
U
U
Kaptur
M
M
Kimber
C
C
Lejman
H
H
D000818:Animals; D001464:Barium / Q000494:pharmacology*; D017609:Barium Compounds; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D005979:Glutathione Peroxidase / Q000097:blood*; D006801:Humans; D007279:Injections, Subcutaneous; D007774:Lactation / Q000378:metabolism; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000097:blood* / Q000187:drug effects; D064586:Selenic Acid; D012643:Selenium / Q000097:blood* / Q000172:deficiency / Q000494:pharmacology*; D018036:Selenium Compounds; D012756:Sheep
D017609:Barium Compounds; D018036:Selenium Compounds; D001464:Barium; D005979:Glutathione Peroxidase; D012643:Selenium; D064586:Selenic Acid; C042078:barium selenate