title: Structure of the rainbow trout metallothionein A gene.
abstract: To investigate the regulation of metallothionein-encoding genes in fish, we have isolated and sequenced the rainbow trout metallothionein-A-encoding gene (tMT-A) by polymerase chain reaction. This gene spans about 1.1 kb, consists of three exons and two introns, and has an A+T-rich 5'-region which contains a TATAAA signal, and two metal responsive elements (MREs). The transcription start point is centered around an A residue 81 nt upstream of the ATG codon.
authors.affiliation: Gene Center, Max-Planck-Institute for Biochemistry, Martinsried, Germany.
authors.forename: Y
authors.initials: Y
authors.lastname: Hong
authors.forename: M
authors.initials: M
authors.lastname: Schartl
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003062:Codon / Q000235:genetics; D005091:Exons; D005796:Genes; D007438:Introns; D008668:Metallothionein / Q000235:genetics*; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction / Q000379:methods; D014337:Trout / Q000235:genetics*
chemical_list: D003062:Codon; D008668:Metallothionein