Experimental substantiation of allogenic tendon tissue transplantation.
Substantiation of transplantation of tendon allografts treated with a new solution showing both sterilizing and preservatory effects was provided in experiments on 84 dogs. The solution prepared on the basis of 0.1% formaldehyde with the addition of dimethyl sulphoxide, monomycin and prednisolone (FDMP) shows a high antimicrobial activity, preserves the structure of the tendons and their elasticity. In their duration, the processes of reconstruction of allografts preserved in FDMP are very similar to autotransplants. Clinical application of preserved tendons on repairing defects in 418 patients proved the method to be highly effective.
Plotnikova
V A
VA
Sverdlovsk Branch, All-Union Kurgan Scientific Centre for Reconstructive Traumatology and Orthopedics, Ministry of Health, Yekaterinoburg, Russia.
Stakheyev
I A
IA
Shtin
V P
VP
D000818:Animals; D004121:Dimethyl Sulfoxide; D004285:Dogs; D015643:Erythromycin Ethylsuccinate; D005557:Formaldehyde; D006801:Humans; D066298:In Vitro Techniques; D011239:Prednisolone; D012996:Solutions; D013710:Tendons / Q000637:transplantation*; D014021:Tissue Preservation
D012996:Solutions; D015643:Erythromycin Ethylsuccinate; D005557:Formaldehyde; D011239:Prednisolone; D004121:Dimethyl Sulfoxide