title: Genomic structure of the putative BTF3 transcription factor.
abstract: On the basis of the amino acid (aa) sequence of the putative BTF3 transcription factor, two complementary DNAs coding for the two proteins, BTF3a and BTF3b, have been cloned from a HeLa cell cDNA library. The two proteins are identical, except that BTF3b lacks the first 44 N-terminal aa present in BTF3a. These proteins originate from the same gene, which contains seven exons, and are the products of alternative splicing. The promoter region, containing a putative TATA box(es) and a CAAT box sequence, was identified. In addition, three other BTF3-like genes were characterized.
authors.affiliation: Laboratoire de Génétique Moléculaire des Eucaryotes du CNRS, U184 de Biologie Moléculaire et de Génie Génétique de l'INSERM, Strasbourg, France.
authors.forename: M
authors.initials: M
authors.lastname: Kanno
authors.forename: C
authors.initials: C
authors.lastname: Chalut
authors.forename: J M
authors.initials: JM
authors.lastname: Egly
mesh_terms: D000595:Amino Acid Sequence; D010582:Bacteriophage lambda / Q000235:genetics; D001483:Base Sequence; D015139:Blotting, Southern; D003001:Cloning, Molecular; D005091:Exons / Q000235:genetics; D015723:Gene Library; D006367:HeLa Cells; D006801:Humans; D007438:Introns / Q000235:genetics; D008969:Molecular Sequence Data; D005810:Multigene Family / Q000235:genetics*; D009687:Nuclear Proteins; D011401:Promoter Regions, Genetic / Q000235:genetics; D012326:RNA Splicing / Q000235:genetics; D015183:Restriction Mapping; D014157:Transcription Factors / Q000737:chemistry / Q000235:genetics*
chemical_list: D009687:Nuclear Proteins; D014157:Transcription Factors; C063552:transcription factor BTF3