Atomic force microscopy of conventional and unconventional nucleic acid structures.
Images of conventional (Watson-Crick base paired) and unconventional (G4 RNA) nucleic acid structures have been obtained by atomic force microscopy. The images are reproducibly generated from samples deposited on freshly cleaved mica. Periodic substructural features are evident in fibres observed in both cases. In the case of G4 RNA, tip-induced formation of large fibres is observed.
Henderson
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Department of Zoology and Genetics, Iowa State University, Ames 50011.
D004247:DNA / Q000648:ultrastructure*; D006150:Guanine Nucleotides / Q000737:chemistry*; D016252:Microscopy, Scanning Tunneling / Q000379:methods*; D012313:RNA / Q000648:ultrastructure*
D006150:Guanine Nucleotides; D012313:RNA; D004247:DNA