Acute lymphoblastic leukemia of Burkitt type (L3) with a (14;18) and an atypical (8;22) translocation.
A 67-year-old man had night sweats, tumor lysis syndrome, and typical histologic and immunophenotypic features of Burkitt-type acute lymphoblastic leukemia (ALL). Cytogenetic analysis showed a previously unreported karyotype, a combination of a (14;18) and an atypical (8;22) translocation.
Smith
S R
SR
Department of Haematology, Freeman Hospital, Newcastle upon Tyne, England.
Bown
N
N
Wallis
J P
JP
D000368:Aged; D002051:Burkitt Lymphoma / Q000235:genetics*; D002883:Chromosomes, Human, Pair 14; D002887:Chromosomes, Human, Pair 18; D002892:Chromosomes, Human, Pair 22; D002898:Chromosomes, Human, Pair 8; D006801:Humans; D007621:Karyotyping; D008297:Male; D014178:Translocation, Genetic