title: Characterization of the progeny of X-ray irradiated males from two Drosophila virilis strains differing in genetic instability.
abstract: Significant effects of X-ray treatment on the increase in the number of phenotypic variations, two visible mutations, and chromosome aberrations were found in the progeny of irradiated males from the D. virilis laboratory stock that is capable of hybrid dysgenesis syndrome induction. This effect is much more pronounced than in the progeny of irradiated males from strong wild-type strains studied. A correlation between genetic instability and chromosome radiosensitivity was outlined. The mechanism of this phenomenon and the possibilities of using the property of genome instability for the productive induction of gene and chromosome damage in radiation mutagenesis experiments are discussed.
authors.affiliation: Department of Molecular Genetics, Academy of Sciences of the Ukraine, Kiev.
authors.forename: I S
authors.initials: IS
authors.lastname: Gubenko
authors.forename: R P
authors.initials: RP
authors.lastname: Subbota
mesh_terms: D000818:Animals; D002875:Chromosomes / Q000528:radiation effects; D003433:Crosses, Genetic; D004330:Drosophila / Q000235:genetics / Q000528:radiation effects*; D005260:Female; D008297:Male; D016296:Mutagenesis / Q000528:radiation effects*; D010641:Phenotype; D012469:Salivary Glands / Q000648:ultrastructure