title: Experimental study on osteoconductive properties of a chitosan-bonded hydroxyapatite self-hardening paste.
abstract: A developmental bone substitute, composed of a chitosan-bonded hydroxyapatite paste and having various possible applications in medical and dental treatments, was evaluated with regard to its osteoconductive properties. Radiographic examination revealed that a bone-like irregular radiopacity appeared in the region of the embedded paste. This was judged histopathologically as the formation of bone tissue with chondral tissue. These data suggest that the paste has osteoconductive properties, and may, therefore, prove clinically useful as a bioactive bone substitute.
authors.affiliation: Department of Oral Pathology, Matsumoto Dental College, Nagano, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Kawakami
authors.forename: M
authors.initials: M
authors.lastname: Antoh
authors.forename: H
authors.initials: H
authors.lastname: Hasegawa
authors.forename: T
authors.initials: T
authors.lastname: Yamagishi
authors.forename: M
authors.initials: M
authors.lastname: Ito
authors.forename: S
authors.initials: S
authors.lastname: Eda
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006882:Hydroxyapatites; D009824:Ointments; D011817:Rabbits; D011859:Radiography
chemical_list: D001672:Biocompatible Materials; D006882:Hydroxyapatites; D009824:Ointments