Chemotherapy-induced acral erythema and acute graft-versus-host disease after allogeneic bone marrow transplantation.
Chemotherapy-induced acral erythema is a rare disorder characterized by a painful and intense erythema of the palms and the soles. In allogeneic bone marrow transplant patients, the differential diagnosis of acute graft-versus-host disease (AGVHD) may be difficult. We describe a case of concurrent acral erythema and AGVHD. The clinical features of both conditions as well as the histological findings on serial skin biopsy specimens are discussed.
Reynaert
H
H
Department of Medical Oncology-Haematology, University Hospital, Belgium.
De Coninck
A
A
Neven
A M
AM
Van Camp
B
B
Schots
R
R
D000208:Acute Disease; D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects; D003875:Drug Eruptions / Q000209:etiology*; D004890:Erythema / Q000139:chemically induced*; D006086:Graft vs Host Disease / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000628:therapy*; D008297:Male