title: Stability and blood compatibility of polylipid/Hb.
abstract: The Polylipid/Hb vesicle is a new artificial red cell (ARC) based on liposome-encapsulated Hb. Advantages are derived from the stabilized liposomal bilayer membranes, obtained by polymerization of 1,2-bis(2,4-octadecadienoyl)-sn-glycero-3-phospho choline (DODPC). Furthermore, blood compatibility in vitro are good.
authors.affiliation: Tsukuba Research Lab., Nippon Oil & Fats Co. Tsukuba, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Morizawa
authors.forename: K
authors.initials: K
authors.lastname: Akama
authors.forename: Y
authors.initials: Y
authors.lastname: Kawakami
authors.forename: E
authors.initials: E
authors.lastname: Tsuchida
mesh_terms: D001777:Blood Coagulation / Q000187:drug effects; D001802:Blood Substitutes / Q000008:administration & dosage* / Q000633:toxicity; D004355:Drug Stability; D004903:Erythrocyte Aggregation / Q000187:drug effects; D006454:Hemoglobins / Q000008:administration & dosage*; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D066298:In Vitro Techniques; D008081:Liposomes; D010974:Platelet Aggregation / Q000187:drug effects; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology; D011108:Polymers
chemical_list: D001802:Blood Substitutes; D006454:Hemoglobins; D008081:Liposomes; D010975:Platelet Aggregation Inhibitors; D011108:Polymers