Morphometrical analysis of GFAP-positive cells in human astrocytomas.
The morphometrical characteristics of human astrocytoma were examined using the shape, size, and intercellular distances of glial fibrillary acidic protein-positive cells in samples from 21 patients with various astrocytomas and normal samples resected during operations on seven patients with other brain tumors. The results showed that astrocytoma cells were rounder than normal astrocytes with fewer processes. Low-grade astrocytomas were smaller than astrocytes or rapid regrowth astrocytomas. Morphological analysis of astrocytoma may be valuable for evaluating the potential migration to adjacent tissue.
Yoshii
Y
Y
Department of Neurological Surgery, University of Tsukuba, Ibaraki.
Narushima
K
K
Tsurushima
H
H
Yanaka
K
K
Hyodo
A
A
Nose
T
T
Sugiyama
K
K
Sakamura
S
S
D000328:Adult; D000368:Aged; D001253:Astrocytes / Q000378:metabolism / Q000473:pathology; D001254:Astrocytoma / Q000378:metabolism / Q000473:pathology*; D001932:Brain Neoplasms / Q000378:metabolism / Q000473:pathology*; D002465:Cell Movement; D005904:Glial Fibrillary Acidic Protein / Q000378:metabolism*; D006801:Humans; D008875:Middle Aged
D005904:Glial Fibrillary Acidic Protein