Interleukin-5 levels of pleural fluid and serum samples in a patient with PIE syndrome.
An increased production of IL-5 was detected in the pleural fluid (7.2 ng/ml) and in the serum samples (53 pg/ml) of a patient with PIE syndrome. Following steroid therapy, pleural fluid disappeared, eosinophilia improved and serum IL-5 concentration became undetectable. These results suggested that eosinophilia in the PIE syndrome is a consequence of increased production of IL-5, especially in the lung.
Matsumoto
R
R
First Department of Internal Medicine, Kumamoto University Medical School, Japan.
Ando
M
M
Kohrogi
H
H
Araki
S
S
Takatsu
K
K
D000328:Adult; D004797:Enzyme-Linked Immunosorbent Assay; D005122:Exudates and Transudates / Q000737:chemistry*; D005260:Female; D006801:Humans; D015848:Interleukin-5 / Q000032:analysis*; D010996:Pleural Effusion / Q000209:etiology / Q000378:metabolism*; D011657:Pulmonary Eosinophilia / Q000097:blood / Q000150:complications / Q000378:metabolism*
D015848:Interleukin-5