title: [Transdermal administration of estrogens in women with the postcastration and climacteric syndromes].
abstract: The authors report on the results of a follow-up of 64 women aged 25-64 years, to whom oestrogens were administered transdermally by means of the preparation Estraderm TTS 25 or 50 for three months. 55 women were treated for postcastration syndrome and nine women for climacteric syndrome. The authors deal with the problems of dosage of the transdermal oestrogen therapy, study the side-effects of treatment and evaluate the results of therapy. In conclusion, they recommend the transdermal form of treatment by Estraderm TTS because of its very good therapeutic effect, acceptability by the patients, and only minimal local and general side-effects.
authors.affiliation: Klinika porodnictví, gynekologie dospĕlých a dĕtí 2. LF UK, Praha.
authors.forename: L
authors.initials: L
authors.lastname: Rotta
authors.forename: E
authors.initials: E
authors.lastname: Matĕchová
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D002979:Climacteric / Q000187:drug effects*; D004958:Estradiol / Q000008:administration & dosage*; D015914:Estrogen Replacement Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D008594:Menopause, Premature; D008875:Middle Aged; D010052:Ovariectomy / Q000009:adverse effects*
chemical_list: D004958:Estradiol