A sexually dimorphic population of galanin-like neurons in the rat lumbar spinal cord: functional implications.
The rat lumbar spinal cord contains a population of galanin- and cholecystokinin-containing neurons which are located dorsolateral to the central canal and project to the thalamus. New data are presented herein which reveal that the number of these neurons, as shown by galanin-like immunostaining, is sexually dimorphic with males containing 62% more of these neurons than females. This is the first demonstration of a sexually dimorphic population of intraspinal neurons which projects to higher CNS centers rather than to peripheral targets.
Newton
B W
BW
Department of Anatomy, University of Arkansas for Medical Sciences, Little Rock 72205.
D000818:Animals; D002452:Cell Count; D002766:Cholecystokinin / Q000032:analysis; D005260:Female; D019004:Galanin; D008297:Male; D009474:Neurons / Q000737:chemistry*; D010455:Peptides / Q000032:analysis*; D051381:Rats / Q000033:anatomy & histology* / Q000502:physiology; D011919:Rats, Inbred Strains / Q000033:anatomy & histology; D012727:Sex Characteristics; D012726:Sexual Behavior, Animal / Q000502:physiology; D013116:Spinal Cord / Q000737:chemistry / Q000166:cytology*; D013133:Spinothalamic Tracts / Q000166:cytology
D010455:Peptides; D019004:Galanin; D002766:Cholecystokinin