[Fc gamma receptors: structure, function, and clinical significance].
Fc gamma receptors are a group of three different receptors with several subtypes. They are widely distributed on many cells of the immune system and contribute to the pathogenesis of immune complex- and autoantibody-mediated diseases such as vasculitis, rheumatoid arthritis, idiopathic thrombocytopenic purpura or autoimmune neutropenia. This review focuses on the structure, distribution and function in Fc gamma receptors and their subtypes.
Witte
T
T
Abteilung Immunologie und Transfusionsmedizin, Medizinische Hochschule Hannover.
Schmidt
R E
RE
D000936:Antigen-Antibody Complex / Q000378:metabolism; D015703:Antigens, CD / Q000502:physiology; D000943:Antigens, Differentiation / Q000145:classification / Q000502:physiology* / Q000648:ultrastructure; D001327:Autoimmune Diseases / Q000276:immunology*; D006801:Humans; D008024:Ligands; D010587:Phagocytosis; D011487:Protein Conformation; D011961:Receptors, Fc / Q000145:classification / Q000502:physiology* / Q000648:ultrastructure; D017452:Receptors, IgG
D000936:Antigen-Antibody Complex; D015703:Antigens, CD; D000943:Antigens, Differentiation; D008024:Ligands; D011961:Receptors, Fc; D017452:Receptors, IgG