[IgM HCV antibody in chronic hepatitis and liver cirrhosis].
To evaluate the role of IgM specific antibody in the diagnosis and monitoring of the patients with chronic hepatitis C, sera from 114 cases with chronic hepatitis C and liver cirrhosis were tested. IgM antibody to hepatitis C virus was detected in 40.0% of CAH, as compared with 21.4% of CIH, 17.4% of LC, 20.0% of LC with HCC. IgM antibody was also detectable in cases with high level of s-ALT. Patients with positive this antibody have high titer of IgG antibody to hepatitis C virus. In summary, testing for this antibody may be useful to evaluate the recurrence or disease activity and may also be helpful in IFN therapy.
Shibuya
A
A
Department of Internal Medicine, Kitasato University School of Medicine, Sagamihara.
Sakurai
K
K
Takeuchi
A
A
Shibata
H
H
D000328:Adult; D006508:Hepatitis Antibodies / Q000032:analysis*; D006526:Hepatitis C / Q000175:diagnosis / Q000276:immunology*; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis*; D007372:Interferons / Q000494:pharmacology; D008103:Liver Cirrhosis / Q000175:diagnosis / Q000276:immunology; D008297:Male
D006508:Hepatitis Antibodies; D007075:Immunoglobulin M; D007372:Interferons