Highly potent and selective inhibition of HIV-1 replication by 6-phenylthiouracil derivatives.
Baba
M
M
Department of Microbiology, Fukushima Medical College, Japan.
Shigeta
S
S
Tanaka
H
H
Miyasaka
T
T
Ubasawa
M
M
Umezu
K
K
Walker
R T
RT
Pauwels
R
R
De Clercq
E
E
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D000998:Antiviral Agents / Q000494:pharmacology* / Q000633:toxicity; D015496:CD4-Positive T-Lymphocytes; D004338:Drug Combinations; D054303:HIV Reverse Transcriptase; D015497:HIV-1 / Q000187:drug effects*; D018894:Reverse Transcriptase Inhibitors; D013329:Structure-Activity Relationship; D013889:Thiouracil / Q000031:analogs & derivatives* / Q000737:chemistry; D014498:Uracil / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000633:toxicity
D000998:Antiviral Agents; D004338:Drug Combinations; D018894:Reverse Transcriptase Inhibitors; C071166:5-ethyl-1-ethoxymethyl-6-(phenylthio)uracil; C060320:6-phenylthiouracil; D014498:Uracil; D013889:Thiouracil; D054303:HIV Reverse Transcriptase