title: Leptomeningeal dissemination of cerebellar pilocytic astrocytoma. Case report.
abstract: A case of surgically treated pilocytic astrocytoma in the cerebellar vermis is reported in a patient who subsequently demonstrated multiple subarachnoid nodular masses in the cerebrum and spinal cord 6 years after the initial surgery. The nodular tumors did not indicate a growth tendency on computerized tomography or magnetic resonance imaging over a 2-year observation period. The histology of the nodular masses in the cerebrum and spinal cord was similar to that of the original tumor. The bromodeoxyuridine labeling index indicated low proliferative activity (0.5%). The peculiar pattern of dissemination of the pilocytic astrocytoma is described.
authors.affiliation: Department of Neurosurgery and Pathology, Tokyo Metropolitan Komagome General Hospital, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Mishima
authors.forename: M
authors.initials: M
authors.lastname: Nakamura
authors.forename: H
authors.initials: H
authors.lastname: Nakamura
authors.forename: O
authors.initials: O
authors.lastname: Nakamura
authors.forename: N
authors.initials: N
authors.lastname: Funata
authors.forename: N
authors.initials: N
authors.lastname: Shitara
mesh_terms: D001254:Astrocytoma / Q000473:pathology / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D002528:Cerebellar Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D002648:Child; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology / Q000556:secondary* / Q000628:therapy