title: Reliability and effectiveness of screening for hearing loss in high risk neonates.
abstract: OBJECTIVE
  To establish the reliability and effectiveness of screening for hearing loss by brainstem auditory evoked potential testing in high risk neonates.
  
  
  METHODS
  Seven year investigation of newborn babies admitted to a special care baby unit and monitored through a regional children's audiology unit.
  
  
  METHODS
  Special care baby unit and children's audiology department, Belfast.
  
  
  METHODS
  405 neonates admitted to the baby unit, during 1 October 1982 to 31 March 1987.
  
  
  METHODS
  Presence of hearing impairment, type and severity of hearing impairment, mortality.
  
  
  RESULTS
  85 children failed the screening test, 62 of whom were followed up. Five children had severe bilateral sensorineural impairment and 12 had conductive impairment requiring surgical intervention. A further 18 had severe neurological disorder detected. The sensitivity of screening was 100% and specificity was 88%. If the procedure was introduced into routine clinical practice the mean age at diagnosis for all children with severe perinatal hearing impairment would be 11 (median 1) months. The mean age at diagnosis with the health visitor screening service was 23 (19) months (difference 10 months, 95% confidence interval 6 to 16 months; p < 0.0001).
  
  
  CONCLUSIONS
  Screening for hearing loss in high risk neonates is highly reliable and cost effective. It also provides valuable neurophysiological information. Routine testing of these infants would result in over half of all children with severe bilateral perinatal sensorineural hearing impairment being identified by 2 months of age. This would make an important contribution to the habilitation of this socially, emotionally, and educationally vulnerable group.
authors.affiliation: Department of Mental Health, Queen's University, Belfast.
authors.forename: R J
authors.initials: RJ
authors.lastname: McClelland
authors.forename: D R
authors.initials: DR
authors.lastname: Watson
authors.forename: V
authors.initials: V
authors.lastname: Lawless
authors.forename: H G
authors.initials: HG
authors.lastname: Houston
authors.forename: D
authors.initials: D
authors.lastname: Adams
mesh_terms: D001034:Apgar Score; D003362:Cost-Benefit Analysis; D003638:Deafness / Q000151:congenital* / Q000175:diagnosis; D016057:Evoked Potentials, Auditory, Brain Stem; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D015997:Neonatal Screening / Q000191:economics / Q000592:standards*; D015203:Reproducibility of Results; D012307:Risk Factors