Atypical malignant mesotheliomas with osseous and cartilaginous differentiation after intraperitoneal injection of various types of mineral fibres in rats.
The histopathological appearance of malignant mesotheliomas with osseous and cartilaginous differentiation is described in detail. Bone and cartilage occurred in mixed and sarcomatoid mesotheliomas which were induced by intraperitoneal injection of various types of asbestos fibres (asbestos cement, crocidolite, UICC-amosite, UICC-chrysotile B, Calidria-chrysotile). Bone or cartilage were found in 32.7% of mixed mesothelioma and in 12.8% of sarcomatoid mesotheliomas.
Rittinghausen
S
S
Department of Histology, Fraunhofer Institute of Toxicology and Aerosol Research, Hannover, Germany.
Ernst
H
H
Muhle
H
H
Mohr
U
U
D000008:Abdominal Neoplasms / Q000209:etiology / Q000473:pathology*; D000818:Animals; D001842:Bone and Bones / Q000187:drug effects / Q000473:pathology*; D002356:Cartilage / Q000187:drug effects / Q000473:pathology*; D002454:Cell Differentiation / Q000187:drug effects; D005260:Female; D007274:Injections, Intraperitoneal; D008654:Mesothelioma / Q000209:etiology / Q000473:pathology* / Q000556:secondary; D008903:Minerals / Q000008:administration & dosage*; D051381:Rats; D017208:Rats, Wistar
D008903:Minerals