title: Amplification of the dihydrofolate reductase gene in methotrexate-resistant Chinese hamster cells.
authors.affiliation: Department of Biochemistry, University of Virginia School of Medicine, Charlottesville 22908.
authors.forename: J L
authors.initials: JL
authors.lastname: Hamlin
mesh_terms: D000818:Animals; D006224:Cricetinae; D003412:Cricetulus / Q000235:genetics*; D004351:Drug Resistance / Q000235:genetics*; D005784:Gene Amplification / Q000235:genetics*; D008727:Methotrexate / Q000494:pharmacology*; D013762:Tetrahydrofolate Dehydrogenase / Q000235:genetics*
chemical_list: D013762:Tetrahydrofolate Dehydrogenase; D008727:Methotrexate