[Clinical study of qianxining in the treatment of 60 cases of yang hyperactivity due to yin deficiency type of hypertension].
60 cases with Yang Hyperactivity due to Yin Deficiency type of hypertension were randomly divided into two groups. One was treated with TCM and the other with WM as control. The results showed that: (1) there were no significant differences in the total effective rate and the amplitude of lowering of blood pressure between two groups; (2) the improvement of symptoms and disturbance of autonomic nerve was significant in TCM group in comparison with control; (3) there were some changes in HR, SV, plasma PRA, TXB2 and 6-keto-PGF1 alpha level in both groups, but the decrease of TXB2/6-keto-PGF1 alpha ratio was significant in TCM group only (P < 0.05); (4) TC and TG in patients with hyperlipemia showed a remarkable drop in TCM group (P < 0.02; P < 0.005). All these revealed that Qianxining was a satisfactory hypotensive remedy and a further exploration of its mechanism is suggested.
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Affiliated Hospital of Xiangtan Iron and Steel Company, Hunan.
D015121:6-Ketoprostaglandin F1 alpha / Q000097:blood; D002784:Cholesterol / Q000097:blood; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D013929:Thromboxane B2 / Q000097:blood; D014280:Triglycerides / Q000097:blood; D016710:Yin Deficiency / Q000097:blood / Q000188:drug therapy*
D004365:Drugs, Chinese Herbal; D014280:Triglycerides; D013929:Thromboxane B2; D015121:6-Ketoprostaglandin F1 alpha; D002784:Cholesterol