Effective prevention of chemotherapy--induced phlebitis by low-dose heparin: a prospective randomised trial.
In a prospective randomised trial patients receiving multiple-day chemotherapy and heparin had significantly fewer local complications at the site of venous access than patients who had chemotherapy alone. The need to move peripheral venous catheters to other sites was decreased significantly, from 36% to 6%. Prophylaxis of phlebitis with low-dose continuous heparin is safe, simple, cheap and effective. It facilitates administration of multiple-day chemotherapy for the patients, the nurses and the physicians.
Thürlimann
B
B
Department of Internal Medicine, Kantonsspital, St. Gallen, Switzerland.
Bachmann
I
I
D000293:Adolescent; D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D005260:Female; D006493:Heparin / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010689:Phlebitis / Q000139:chemically induced / Q000517:prevention & control*; D011446:Prospective Studies
D006493:Heparin