[Hepatitis C infection and liver cell carcinoma].
Epidemiological data disclose that the incidence of hepatocellular carcinoma (HCC) is increasing world-wide, whereas the number of cases positive for HBV-marker has remained almost stable, at least in Japan. Data from Europe show positivity of antibodies against hepatitis C virus (anti-HCV) in 72% of HBsAg negative cases with HCC and in 28% of patients positive for HBsAg. Nearly 90% of HBsAg negative patients with HCC showed a histology of cirrhosis or chronic active hepatitis in the noncancerous liver. Almost every third patient had a history of blood transfusion. These results suggest an increasing incidence of HCV - associated HCC's, as it already has been shown for patients suffering from chronic HBV infection.
Maier
K P
KP
Städt. Krankenanstalt Esslingen, Akademisches Lehrkrankenhaus, Universität Tübingen.
D000956:Antigens, Viral / Q000302:isolation & purification; D006528:Carcinoma, Hepatocellular / Q000209:etiology* / Q000276:immunology; D006514:Hepatitis B Surface Antigens / Q000302:isolation & purification; D006526:Hepatitis C / Q000150:complications*; D018936:Hepatitis C Antigens; D006801:Humans; D008113:Liver Neoplasms / Q000209:etiology* / Q000276:immunology
D000956:Antigens, Viral; D006514:Hepatitis B Surface Antigens; D018936:Hepatitis C Antigens