title: Beta-human chorionic gonadotropin and alpha-fetoprotein in central and peripheral venous blood of patients with testicular tumors.
abstract: From January 1989 to June 1991, 18 patients ranging in age from 19 to 41 (mean 34) years with testicular tumor were examined. 14 patients had seminoma (11 typical and 3 spermatocytic) and 4 patients had a mixed form (2 seminoma + embryonal tumor and 2 seminoma + teratocarcinoma). Serum levels of beta-human chorionic gonadotropin and alpha-fetoprotein from peripheral venous blood and from spermatic venous vessel were evaluated in every patient. All patients with seminoma and in a patient with mixed tumor (seminoma + embryonal tumor) the markers were regular. The increase of the markers was found in the peripheral and in spermatic blood of 3 patients (2 seminoma + embryonal carcinoma and 1 seminoma + teratocarcinoma). For these reasons the values of spermatic vessels are an important confirmation of the level of peripheral markers.
authors.affiliation: Division of Urology, O.C. Morgagni, Forlì, Italy.
authors.forename: T
authors.initials: T
authors.lastname: Zenico
authors.forename: M
authors.initials: M
authors.lastname: Zoli
authors.forename: M
authors.initials: M
authors.lastname: Fiori
authors.forename: F
authors.initials: F
authors.lastname: Fabbri
authors.forename: C
authors.initials: C
authors.lastname: Tamburini
authors.forename: G
authors.initials: G
authors.lastname: Maltoni
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood*; D006063:Chorionic Gonadotropin / Q000097:blood*; D006801:Humans; D008297:Male; D013736:Testicular Neoplasms / Q000097:blood*; D014680:Veins; D000509:alpha-Fetoproteins / Q000378:metabolism*
chemical_list: D014408:Biomarkers, Tumor; D006063:Chorionic Gonadotropin; D000509:alpha-Fetoproteins