title: Syntheses of a glycerophospholipid, C16-platelet activating factor and a palmitoyl analogue of M-5, an anti-inflammatory glyceroglycolipid.
abstract: From a chiral C4-epoxide (-)-3, which is one of the synthons in our synthetic strategy for complex lipids, a glycerophospholipid C16-platelet activating factor (C16-PAF, 1) and a palmitoyl analogue (2) of an anti-inflammatory glyceroglycolipid M-5, which was previously isolated from the Okinawan marine sponge Phyllospongia foliascens, have been synthesized.
authors.affiliation: Faculty of Pharmaceutical Sciences, Osaka University, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Shibuya
authors.forename: K
authors.initials: K
authors.lastname: Kawashima
authors.forename: N
authors.initials: N
authors.lastname: Narita
authors.forename: I
authors.initials: I
authors.lastname: Kitagawa
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis*; D005994:Glycerophosphates / Q000138:chemical synthesis*; D006017:Glycolipids / Q000138:chemical synthesis*; D010169:Palmitic Acids / Q000138:chemical synthesis*; D010743:Phospholipids / Q000138:chemical synthesis*; D010972:Platelet Activating Factor / Q000138:chemical synthesis*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D005994:Glycerophosphates; D006017:Glycolipids; D010169:Palmitic Acids; D010743:Phospholipids; D010972:Platelet Activating Factor; C016476:glyceroglucolipids