title: Donor heart preservation survey.
abstract: A questionnaire requesting information on donor heart preservation technique and outcomes during the first 6 months of 1990 was circulated to heart transplantation centers worldwide. Seventy-nine usable replies representing 1371 clinical transplant operations were received. Twenty-seven percent of the respondents reported using some form of donor pretreatment. Most (90%) used single flush cardioplegic induction with the use of eight different types of cardioplegic solutions, only 5% of which were oxygenated. Six different types of storage media were used, and the coolant was melting ice in 66% of the centers. Storage temperatures between 0 degrees C and 7 degrees C were reported, with 78% of the respondents using 4 degrees C storage. Fifty-five percent of the centers used some form of reperfusion modification. No statistically significant associations were noted between outcome and technique, apart from the use of storage medium in which the use of cardioplegic solution conferred a 2.5 times increase in deaths compared with cold saline. The results of this questionnaire provide evidence for the diversity of techniques currently used for donor heart preservation, reflecting the lack of any one optimal method.
authors.affiliation: Papworth Hospital, Cambridge, UK.
authors.forename: D
authors.initials: D
authors.lastname: Wheeldon
authors.forename: L
authors.initials: L
authors.lastname: Sharples
authors.forename: J
authors.initials: J
authors.lastname: Wallwork
authors.forename: T
authors.initials: T
authors.lastname: English
mesh_terms: D002314:Cardioplegic Solutions; D003625:Data Collection; D006324:Heart Arrest, Induced; D016027:Heart Transplantation / Q000401:mortality; D006801:Humans; D015425:Myocardial Reperfusion; D009926:Organ Preservation / Q000379:methods / Q000706:statistics & numerical data; D013696:Temperature
chemical_list: D002314:Cardioplegic Solutions