title: [Allergic reactions to teniposide (VM-26) in children with neoplasms].
abstract: Allergic reactions of dramatic intensity were observed in 5 children treated with Teniposide (VM-26) for acute lymphoblastic leukaemia and histiocytosis X. In the further treatment this drug was replaced with epoxide, a cytostatic agent which is also a podophyllin derivative but in other chemical formulation. In none of these patients the allergic reaction returned.
authors.affiliation: Katedra i I Klinika Chorób Dzieci Ak. Med., Bydgoszczy.
authors.forename: M
authors.initials: M
authors.lastname: Wysocki
authors.forename: A
authors.initials: A
authors.lastname: Nowaczyk-Michalak
authors.forename: O
authors.initials: O
authors.lastname: Pilecki
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000188:drug therapy*; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy*; D013713:Teniposide / Q000009:adverse effects*
chemical_list: D013713:Teniposide
vernacular_title: Reakcje alergiczne na teniposide (VM-26) u dzieci z choroba nowotworowa.