title: Primary meningeal lymphoma in a horse.
abstract: Primary meningeal lymphoma was diagnosed in an 18-year-old Morgan gelding. The horse was examined because of a 3-day history of progressive ataxia and weakness. The gait abnormalities were worse on the left side, and the pelvic limbs were more affected than the thoracic limbs. Additional findings included signs of depression, miosis of the left pupil, ptosis of the left upper eyelid, and areas of muscle atrophy on the left side of the neck and over the dorsal aspect of the left scapula. Inflammatory changes were evident in the CSF. At necropsy, there was diffuse and irregular thickening of the dura mater along the entire spinal cord. Histologic examination revealed infiltration of the leptomeninges with neoplastic lymphocytes.
authors.affiliation: Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610.
authors.forename: G D
authors.initials: GD
authors.lastname: Lester
authors.forename: R J
authors.initials: RJ
authors.lastname: MacKay
authors.forename: B
authors.initials: B
authors.lastname: Smith-Meyer
mesh_terms: D000818:Animals; D001259:Ataxia / Q000209:etiology / Q000662:veterinary; D006734:Horse Diseases / Q000209:etiology / Q000473:pathology*; D006736:Horses; D008223:Lymphoma / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D008297:Male; D008577:Meningeal Neoplasms / Q000150:complications / Q000473:pathology / Q000662:veterinary*