Coumadin skin necrosis. Pedal manifestations.
The idiosyncratic dermatologic reaction to coumarin-like agents, most notably, Coumadin (warfarin sodium) has been well described in the world's literature. Although the incidence is reported to be less than 0.1% of patients treated with Coumadin, pedal cases tend to be striking and their treatment seemingly tenuous.
Viegas
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GV
Reconstructive Foot Service, University of Chicago Hospital, IL.
D000368:Aged; D005260:Female; D005528:Foot; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D009336:Necrosis / Q000139:chemically induced / Q000188:drug therapy / Q000473:pathology; D009765:Obesity / Q000150:complications; D012867:Skin / Q000473:pathology*; D014859:Warfarin / Q000009:adverse effects*
D014859:Warfarin; D006493:Heparin