The effects of spontaneous luteinizing hormone surges on superovulatory cycles.
OBJECTIVE
To determine the effect of a spontaneous luteinizing hormone (LH) surge on the cycle fecundity during superovulation induction.


METHODS
Superovulatory cycles of patients with various diagnoses are retrospectively compared.


METHODS
Reproductive Endocrinology Outpatient Clinic.


METHODS
A total of 1,185 superovulatory cycles from July 1, 1982 until November 1, 1991 are compared.


METHODS
The probability of achieving a pregnancy per treatment cycle.


RESULTS
Patients with unexplained infertility and hyperprolactinemia were more likely to have a spontaneous LH surge during superovulation than patients with either endometriosis or polycystic ovarian disease. However, the cycle fecundity rate did not differ whether or not an LH surge occurred, regardless of the diagnosis.


CONCLUSIONS
Spontaneous onset of an LH surge during superovulation induction does not influence the chances for pregnancy.
Akin
J W
JW
Department of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis.
Shepard
M K
MK
Sandefur
H J
HJ
Cox
K K
KK
D000328:Adult; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000097:blood / Q000628:therapy; D007986:Luteinizing Hormone / Q000097:blood / Q000502:physiology*; D008596:Menotropins / Q000627:therapeutic use; D012189:Retrospective Studies; D013480:Superovulation
D008596:Menotropins; D007986:Luteinizing Hormone