title: Sharing of virulence-associated properties at the phenotypic and genetic levels between enteropathogenic Escherichia coli and Hafnia alvei.
abstract: Seven strains of Hafnia alvei isolated from diarrhoeal stools of children resembled enteropathogenic Escherichia coli (EPEC) in that they produced attaching-effacing (AE) lesions in rabbit ileal loops and fluorescent actin staining in infected HEp-2 cells. In addition, a DNA probe from a chromosomal gene required by EPEC to produce AE lesions, hybridised to chromosomal DNA from all seven H. alvei strains. These findings indicate that there is a sharing of virulence-associated properties at the phenotypic and genetic levels by H. alvei and EPEC. H. alvei strains with these properties should be considered diarrhoeagenic.
authors.affiliation: International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka.
authors.forename: M J
authors.initials: MJ
authors.lastname: Albert
authors.forename: S M
authors.initials: SM
authors.lastname: Faruque
authors.forename: M
authors.initials: M
authors.lastname: Ansaruzzaman
authors.forename: M M
authors.initials: MM
authors.lastname: Islam
authors.forename: K
authors.initials: K
authors.lastname: Haider
authors.forename: K
authors.initials: K
authors.lastname: Alam
authors.forename: I
authors.initials: I
authors.lastname: Kabir
authors.forename: R
authors.initials: R
authors.lastname: Robins-Browne
mesh_terms: D001422:Bacterial Adhesion; D015139:Blotting, Southern; D002648:Child; D003967:Diarrhea / Q000382:microbiology*; D004755:Enterobacteriaceae / Q000235:genetics / Q000472:pathogenicity*; D004756:Enterobacteriaceae Infections / Q000382:microbiology*; D004926:Escherichia coli / Q000235:genetics / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000382:microbiology*; D005243:Feces / Q000382:microbiology; D006367:HeLa Cells; D006801:Humans; D007082:Ileum / Q000382:microbiology; D010641:Phenotype; D010957:Plasmids; D014774:Virulence