title: Unidimensionality of alcohol dependence syndrome?
abstract: To evaluate the coherence of Alcohol Dependence Syndrome (ADS), as per DSM-III-R criteria, 72 and 223 subjects with alcohol dependence disorder from Hospital and Community settings, respectively, were interviewed. Nine DSM-III-R criteria assessing the dependence syndrome were factor-analysed. A single factor model provides an adequate description of the interrelationship among the nine criteria and supports the coherence of the dependence syndrome for the hospital sample but not for the community. A two factor model, namely 'withdrawal' and 'social', fits the community data. When the criteria were combined into cumulative scales, they formed good approximations of unidimensional Guttman scales for both the hospital and community settings. For hospital data, preoccupation was the highly central criterion (lambda = 0.95) in defining the dependence syndrome while 'can't stop' (v = 0.11) measured the most severe level of dependence. In the community the 'socially dysfunctional use' identified as a separate secondary factor measured the most severe level of dependence.
authors.affiliation: Department of Psychiatry and Drug Dependence Treatment Centre, All India Institute of Medical Sciences, New Delhi.
authors.forename: D
authors.initials: D
authors.lastname: Mohan
authors.forename: R
authors.initials: R
authors.lastname: Ray
authors.forename: H
authors.initials: H
authors.lastname: Sethi
mesh_terms: D000293:Adolescent; D000328:Adult; D000437:Alcoholism / Q000145:classification / Q000175:diagnosis* / Q000523:psychology; D003906:Developing Countries; D005163:Factor Analysis, Statistical; D006801:Humans; D007194:India; D008297:Male; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data*; D011594:Psychometrics; D012016:Reference Values; D013577:Syndrome