Pancreatitis induced by mesalamine.
Sulphasalazine is an active agent in the treatment of chronic inflammatory bowel disease, but there are a number of well-known side effects, including pancreatitis. The newer 5-ASA agents are thought to be equally effective but less toxic. Here we describe a patient who developed a pancreatitis due to mesalamine; this was confirmed at rechallenge.
Erdkamp
F
F
Department of Internal Medicine, Catharina Hospital, Eindhoven, Netherlands.
Houben
M
M
Ackerman
E
E
Breed
W
W
van Spreeuwel
J
J
D000208:Acute Disease; D000328:Adult; D000636:Aminosalicylic Acids / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy; D019804:Mesalamine; D010195:Pancreatitis / Q000139:chemically induced*
D000636:Aminosalicylic Acids; D019804:Mesalamine