title: Global left ventricular performance and regional systolic function after suture annuloplasty for chronic mitral regurgitation.
abstract: BACKGROUND
  In surgery for chronic mitral regurgitation, the mitral subvalvular apparatus, including annulus, may play an important role in preserving left ventricular (LV) performance. The suture annuloplasty for mitral regurgitation allows annular contraction of the mitral valve. The potential effects of suture annuloplasty on the postoperative LV performance have not been fully defined.
  
  
  RESULTS
  Global and regional LV function in 12 patients with suture annuloplasty were compared with 12 patients with conventional mitral valve replacement (MVR). Cineangiography and echocardiography were obtained before and 10.8 months after surgery. End-diastolic volume index and end-systolic volume index decreased significantly in both groups after surgery (p < 0.01). Ejection fraction remained unchanged in the suture annuloplasty group, whereas it decreased significantly in the MVR group after surgery (p < 0.01). There was a significant inverse relation between ejection fraction and end-systolic wall stress in the two groups after surgery (suture annuloplasty group, r = -0.69, p = 0.01; MVR group, r = -0.60, p = 0.04). The intercept on the y axis was significantly (p < 0.005) higher in the suture annuloplasty group than in the MVR group. In the suture annuloplasty group, cross-sectional area ejection fraction at the mitral valve level and at the papillary muscle level by LV two-dimensional echocardiography remained unchanged after surgery. In the MVR group, they decreased significantly after surgery (p < 0.01). There was a significant correlation between the cross-sectional area ejection fraction and the global ejection fraction at both levels after surgery. Therefore, the improvement of the regional wall motion can be attributed to the improvement of the global LV performance after suture annuloplasty.
  
  
  CONCLUSIONS
  These data suggest that suture annuloplasty can provide more desirable postoperative LV systolic performance than conventional MVR by preserving both the contraction of the mitral annulus and the mitral valvular-ventricular interaction.
authors.affiliation: Division of Cardiovascular Surgery, Sakurabashi Watanabe Hospital, Osaka, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Sakai
authors.forename: S
authors.initials: S
authors.lastname: Nakano
authors.forename: K
authors.initials: K
authors.lastname: Taniguchi
authors.forename: S
authors.initials: S
authors.lastname: Sakaki
authors.forename: N
authors.initials: N
authors.lastname: Hirata
authors.forename: H
authors.initials: H
authors.lastname: Shintani
authors.forename: Y
authors.initials: Y
authors.lastname: Shimazaki
authors.forename: Y
authors.initials: Y
authors.lastname: Kawashima
authors.forename: H
authors.initials: H
authors.lastname: Matsuda
mesh_terms: D004452:Echocardiography; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000503:physiopathology / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000453:epidemiology / Q000503:physiopathology* / Q000601:surgery*; D012189:Retrospective Studies; D013318:Stroke Volume / Q000502:physiology; D013536:Suture Techniques; D013599:Systole / Q000502:physiology*; D016277:Ventricular Function, Left / Q000502:physiology*