[An epidemiological study on Bordetella pertussis infection in Fukui Prefecture from 1986 to 1991--especially observation on the patients of culture-confirmed pertussis].
In order to clarify the epidemiological situation of whooping cough in Fukui prefecture, 478 nasopharyngeal swabs from patients with pertussis-like symptoms were submitted to bacterial isolation. Laboratory data of these patients with clinical informations at the departments of pediatrics of 6 hospitals in Fukui city from June 1986 to May 1991 were also examined in relation to the above bacterial isolation. The results observed in culture positive patients were as follows: 1) B. pertussis were isolated from 83 patients (41 men and 42 women). 2) Isolates were classified into 3 serotypes. Most dominant type was 1.3.6 (80 strains, 96.4%), and followed by 1 (2 strains) and 1.4.5 (1 strain). 3) Most of the patients were non-vaccinees less than 3 years of age (69 of 83 (83.1%). This evidence suggested strongly that pertussis vaccine was highly effective to prevent pertussis. 4) The patients under 3 years of age whose leucocyte counts were > or = 15000/mm3 and lymphocyte rate to total leucocyte were > or = 70% in their peripheral blood at the time of nasopharyngeal swabs sampling were only 49.3% (33 of 67). Therefore, diagnosis of pertussis by leucocyte findings alone were considered to be inadequate. 5) The area of the patient's residence covered 7 regions of 8 health center districts in Fukui prefecture. The areal distribution of the number of patients from June 1986 to May 1991 was relatively proportional to the population of each district.(ABSTRACT TRUNCATED AT 250 WORDS)
Kobayashi
K
K
Fukui Prefectural Institute of Public Health.
Maegawa
T
T
Takeuchi
F
F
D000293:Adolescent; D000367:Age Factors; D001886:Bordetella pertussis / Q000145:classification / Q000302:isolation & purification*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007564:Japan / Q000453:epidemiology; D007958:Leukocyte Count; D008297:Male; D010567:Pertussis Vaccine; D012703:Serotyping; D014611:Vaccination; D014917:Whooping Cough / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control
D010567:Pertussis Vaccine