Evaluating the palatability of alcohol for rats with measures of taste reactivity, consumption, and lick rate.
In two experiments, rats were presented with water and six concentrations of alcohol (0.5%, 3%, 6%, 9%, 12%, and 15%, v/v) under conditions of mild fluid deprivation. Their responses were measured using taste reactivity (fluids infused directly into the mouth), consumption, and lick rate (both in a voluntary drinking situation). Results in both experiments showed that the number of overall ingestive responses was relatively high and consistent across all alcohol concentrations and water; aversive responding was low for all solutions. During one-bottle, 10-min tests, rats consumed the three lowest concentrations of alcohol (0.5%, 3%, and 6%) and water at an equal level. There was an abrupt drop in the amount of alcohol consumed at 9% and a continued decrease at the two highest concentrations. Lick rates for alcohol (measured only in Experiment 2) fell into three general patterns: 0.5%, 3%, and 6% produced almost identical, negatively accelerating curves consistently above that of water which was linear; lick rates for 9% and 12% rose initially but, at approximately 2 min, became flat; the 15% solution produced a low lick rate throughout the 5-min period. There were significant correlations between lick rate and amount consumed but, contrary to expectations, no significant correlations were found between taste reactivity and the other two measures (consumption and lick rate). These results suggest that taste reactivity to alcohol solutions may be reflective of processes different from those that regulate licking behavior or actual consumption.
Bice
P J
PJ
Department of Psychology, Kansas State University, Manhattan 66506-5302.
Kiefer
S W
SW
Elder
N B
NB
D000428:Alcohol Drinking; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004327:Drinking Behavior; D000431:Ethanol / Q000008:administration & dosage*; D005518:Food Preferences; D008297:Male; D051381:Rats; D013649:Taste
D000431:Ethanol