[Disseminated lupus erythematosus induced by carbamazepine (Tegretol)].
A 20-year-old man is described with drug-induced lupus erythematosus (DILE) induced by carbamazepine prescribed for epilepsy. The symptoms consisted mainly of arthritis and largely disappeared when carbamazepine was replaced by oxcarbazepine. With a simple decision scheme based on serological findings, differentiation between (idiopathic) systemic lupus erythematosus and DILE is possible.
Boon
D M
DM
Afd. Reumatologie, Dr. Daniel den Hoed Kliniek, Rotterdam.
van Parys
J A
JA
Swaak
A J
AJ
D000328:Adult; D000974:Antibodies, Antinuclear / Q000302:isolation & purification; D000927:Anticonvulsants / Q000627:therapeutic use; D002220:Carbamazepine / Q000009:adverse effects* / Q000031:analogs & derivatives / Q000627:therapeutic use; D004827:Epilepsy / Q000188:drug therapy; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced* / Q000175:diagnosis; D008297:Male; D000078330:Oxcarbazepine
D000974:Antibodies, Antinuclear; D000927:Anticonvulsants; D002220:Carbamazepine; D000078330:Oxcarbazepine
Lupus erythematosus disseminatus geïnduceerd door carbamazepine (Tegretol).