Cytogenetic and fluorescence in situ hybridization analysis of breast fibroadenomas.
We report cytogenetic and fluorescence in situ hybridization (FISH) analysis findings in 7 patients with breast fibroadenomas (FA). Three patients were cytogenetically abnormal. One patient had a translocation t(3;5)(p22;q13), the second had trisomy 8, and the third two clones, 47, XX, +11 and 47,XX, +10.
Stephenson
C F
CF
Cancer Center of Southwest Biomedical Research Institute, Scottsdale, AZ 85251.
Davis
R I
RI
Moore
G E
GE
Sandberg
A A
AA
D000232:Adenofibroma / Q000235:genetics*; D000293:Adolescent; D000328:Adult; D001943:Breast Neoplasms / Q000235:genetics*; D002879:Chromosomes, Human, Pair 10; D002880:Chromosomes, Human, Pair 11; D002893:Chromosomes, Human, Pair 3; D002895:Chromosomes, Human, Pair 5; D002898:Chromosomes, Human, Pair 8; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D008875:Middle Aged; D014178:Translocation, Genetic; D014314:Trisomy