title: Safety of ondansetron.
abstract: Ondansetron is a novel 5-HT3 receptor antagonist used for the treatment of cytotoxic-induced emesis and postoperative nausea and vomiting. Safety data from volunteer studies, non-emesis development studies, studies in the treatment of cytotoxic-induced emesis and postoperative nausea and vomiting, and spontaneous case reports, all indicate that ondansetron is well tolerated and has an excellent safety profile. There are no known interactions of ondansetron with other drugs, and no interference with postoperative recovery.
authors.affiliation: Glaxo Group Research, Greenford, Middlesex, UK.
authors.forename: W M
authors.initials: WM
authors.lastname: Castle
authors.forename: A J
authors.initials: AJ
authors.lastname: Jukes
authors.forename: C J
authors.initials: CJ
authors.lastname: Griffiths
authors.forename: S M
authors.initials: SM
authors.lastname: Roden
authors.forename: Y L
authors.initials: YL
authors.lastname: Greenstreet
mesh_terms: D004361:Drug Tolerance; D006801:Humans; D017294:Ondansetron / Q000009:adverse effects / Q000627:therapeutic use*; D012449:Safety
chemical_list: D017294:Ondansetron