Early insulin response after food intake in geese.
Plasma glucose and insulin levels were measured in chronically catheterized, freely moving, undisturbed geese, which were offered a free standard meal after an overnight fast. The insulin level markedly rose within the first minute after the start of food ingestion, whereas plasma glucose did not increase. This early insulin response was not correlated with the size of the meal. In contrast, both postabsorptive insulin response and plasma glucose changes were dependent on meal size. When a small amount of food (2-6 g) was eaten, insulin returned to basal level within 30 min, whereas plasma glucose remained unchanged. Larger meals (15-20 g) maintained plasma insulin at a higher level and induced a sustained rise of plasma glucose. These results indicate that there is a cephalic phase of insulin secretion at the beginning of the meal in birds as previously described in mammals.
Karmann
H
H
Centre d'Ecologie et Physiologie Energétique, l'Université Louis Pasteur, Strasbourg, France.
Rideau
N
N
Zorn
T
T
Malan
A
A
Le Maho
Y
Y
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D004435:Eating / Q000502:physiology*; D005777:Geese / Q000097:blood / Q000502:physiology*; D007328:Insulin / Q000097:blood*; D009994:Osmolar Concentration; D013997:Time Factors
D001786:Blood Glucose; D007328:Insulin