title: Malignant melanoma of the skin among workers in a telecommunications industry: mortality study 1976-83.
abstract: An incidence study of malignant melanoma of the skin (MMS), conducted previously among the workers of four plants of a large telecommunications industry located in Montreal, Canada, showed a standardised incidence ratio of 2.7 (95% confidence interval (95% CI) 1.3-5.02) for the years 1976 to 1983. To describe more precisely the magnitude of the problem a mortality study was started among the same population (n = 9590) for the same period (1976-83). At the end of 1983, 9180 workers were alive, 261 were dead, and 149 (1.5%) were not traced. Standardised mortality ratios (SMRs) for all causes of death were surprisingly low for men (SMR = 0.57; 95% CI 0.50-0.64) and women (SMR = 0.56; 95% CI 0.37-0.82). The SMRs for major causes of death were also less than expected. These results may be explained by a pronounced selection bias (healthy worker effect) and by the short duration of follow up (eight years). For MMS, two deaths occurred among men (SMR = 2.00; 95% CI 0.24-7.22) and one among women (SMR = 4.81; 95% CI 0.12-26.78). A third man who died of MMS was miscoded as having a primary pulmonary melanoma. Including this case increased the SMR for MMS to 3.00 (95% CI 0.62-8.77; p = 0.08). Polyvinyl chloride and polychlorinated biphenyls were used in the plants and some of the workers did soldering. A planned case-control study will investigate other possible exposures at work.
authors.affiliation: Department of Community Health, Sacre-Coeur Hospital, Montreal, Quebec, Canada.
authors.forename: L
authors.initials: L
authors.lastname: DeGuire
authors.forename: D
authors.initials: D
authors.lastname: Cyr
authors.forename: G
authors.initials: G
authors.lastname: Thériault
authors.forename: S
authors.initials: S
authors.lastname: Provencher
authors.forename: H
authors.initials: H
authors.lastname: Iturra
authors.forename: B W
authors.initials: BW
authors.lastname: Case
mesh_terms: D002170:Canada / Q000453:epidemiology; D002423:Cause of Death; D015331:Cohort Studies; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008545:Melanoma / Q000401:mortality*; D009784:Occupational Diseases / Q000401:mortality*; D012878:Skin Neoplasms / Q000401:mortality*; D013685:Telecommunications