title: Isolated splenic metastasis from rectal carcinoma.
abstract: Splenic metastasis is a late manifestation of disseminated disease. Focal metastatic splenic involvement, however, without evidence of additional systemic disease, is unique. Review of the literature yielded only one case of isolated splenic metastasis incidental to rectal carcinoma. We have reported an additional case of isolated solitary splenic metastasis from primary adenocarcinoma of the rectum. Theoretically, certain anatomic, histologic, and functional splenic attributes may limit splenic involvement from metastatic disease.
authors.affiliation: Department of Surgery, Carlos Center for Surgical Anatomy, Emory University School of Medicine, Atlanta, GA 30322.
authors.forename: P J
authors.initials: PJ
authors.lastname: Capizzi
authors.forename: K B
authors.initials: KB
authors.lastname: Allen
authors.forename: J R
authors.initials: JR
authors.lastname: Amerson
authors.forename: J E
authors.initials: JE
authors.lastname: Skandalakis
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D002272:Carcinoembryonic Antigen / Q000097:blood; D003125:Colostomy; D005260:Female; D006801:Humans; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D002272:Carcinoembryonic Antigen