[A case of suicide by an intravenous injection of pancuronium].
A 25-year-old male anesthesiologist was found dead in his room with an intravenous drip line connected with his leg. There were several empty ampules of pancuronium, midazolam and buprenorphine around him. Pancuronium and midazolam in the blood and urine samples collected at postmortem examination were detected by spectrofluorometry and ECD-gas chromatography, respectively. The concentrations of pancuronium and midazolam were 0.3 micrograms/g and 0.12 micrograms/g in the blood, respectively; 0.9 micrograms/g and 0.05 micrograms/g in the urine, respectively. The cause of death was determined to be asphyxia due to respiratory muscle paralysis caused by pancuronium.
Yashiki
M
M
Department of Legal Medicine, Hiroshima University School of Medicine, Japan.
Miyazaki
T
T
Iwasaki
Y
Y
Taniguchi
T
T
Kojima
T
T
D000328:Adult; D001237:Asphyxia / Q000209:etiology; D002849:Chromatography, Gas; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008874:Midazolam / Q000032:analysis; D010197:Pancuronium / Q000008:administration & dosage / Q000506:poisoning*; D012133:Respiratory Paralysis / Q000139:chemically induced / Q000150:complications; D013050:Spectrometry, Fluorescence; D013405:Suicide
D010197:Pancuronium; D008874:Midazolam