title: Renal dysfunction associated with infection of Leptospira interrogans in a horse.
abstract: Renal failure associated with infection of Leptospira interrogans was detected in a horse. Fever, leukocytosis, pyuria, isosthenuria, and azotemia were suggestive of an inflammatory urinary tract disease. Despite persistent pyuria, no bacteria were found during routine microscopic examinations or bacteriologic culturing of urine. A fluorescent antibody examination of the urine was positive for L interrogans. Serologic testing during a 6-month period, supported an acute infection with L interrogans serovar pomona. Treatment with intravenously administered fluids and antimicrobials resulted in clinical recovery. Leptospira interrogans serovar pomona has been reported as causing fever, uveitis, or abortion in horses.
authors.affiliation: Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.
authors.forename: T J
authors.initials: TJ
authors.lastname: Divers
authors.forename: T D
authors.initials: TD
authors.lastname: Byars
authors.forename: S J
authors.initials: SJ
authors.lastname: Shin
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology / Q000628:therapy / Q000662:veterinary*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005440:Fluid Therapy / Q000662:veterinary; D006734:Horse Diseases / Q000209:etiology* / Q000628:therapy; D006736:Horses; D007668:Kidney / Q000503:physiopathology; D007921:Leptospira interrogans / Q000302:isolation & purification*; D007922:Leptospirosis / Q000150:complications / Q000628:therapy / Q000662:veterinary*; D008297:Male
chemical_list: D000900:Anti-Bacterial Agents