Chemoprevention of cancer: protease inhibitors.
1. The defense of the organism against cancer by inhibitors of proteolytic enzymes which are able to block the metastasizing stage of the disease is reviewed. 2. The contemporary views on the possible mechanisms of the process of prevention on both molecular and cellular levels are presented.
Hocman
G
G
Institute of Preventive and Clinical Medicine, Bratislava, Czechoslovakia.
D000818:Animals; D016588:Anticarcinogenic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002460:Cell Line; D002471:Cell Transformation, Neoplastic / Q000187:drug effects*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000517:prevention & control*; D011480:Protease Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*
D016588:Anticarcinogenic Agents; D011480:Protease Inhibitors