title: POEMS syndrome--a case report.
abstract: POEMS syndrome is a multisystem disorder associated with polyneuropathy, organomegaly, endocrinopathy, a monoclonal protein (M-protein), and skin changes. The authors describe a patient with POEMS syndrome who had osteosclerotic myeloma confirmed by open bone biopsy. Magnetic resonance imaging (MRI) showed discrete lesions of low signal intensity in both T1 and T2-weighted images. This patient is now being successfully treated with melphalan and prednisone with much improvement in skin thickening and sensory change in the lower extremities.
authors.affiliation: Department of Neurology, College of Medicine, Dong-A University, Korea.
authors.forename: J W
authors.initials: JW
authors.lastname: Kim
authors.forename: S K
authors.initials: SK
authors.lastname: Lee
authors.forename: K M
authors.initials: KM
authors.lastname: Ha
authors.forename: K H
authors.initials: KH
authors.lastname: Kim
authors.forename: G Y
authors.initials: GY
authors.lastname: Joh
authors.forename: H J
authors.initials: HJ
authors.lastname: Kim
authors.forename: S O
authors.initials: SO
authors.lastname: Yang
authors.forename: S H
authors.initials: SH
authors.lastname: Hong
mesh_terms: D000328:Adult; D001706:Biopsy; D005272:Femur Neck / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009101:Multiple Myeloma / Q000150:complications / Q000473:pathology; D016878:POEMS Syndrome / Q000150:complications / Q000175:diagnosis*