[Antiatherogenic action of corn oil in experimental atherosclerosis].
Therapeutic effect of corn oil was studied in rabbits with alimentary atherosclerosis. Corn oil was administered (2 ml/kg, 30 days) after the completion of cholesterol diet unlike studies, where they were administered simultaneously. Total cholesterol, apoB-lipoprotein cholesterol and triglycerides decreased more intensively in rabbits fed by corn oil than in control group. No changes in high-density lipoprotein cholesterol were observed. The most pronounced effect was noted in aorta morphological analysis: an aorta damage degree was 4.8% as compared with 52.9% in the control group. The results show that available plant oils with omega-6 polyunsaturated fatty acids (PUFA), in particular corn oil, may as well as omega-3 PUFA be used as the base for antiatherogenic preparations.
Lopukhin
Iu M
IuM
Sdvigova
A G
AG
Torkhovskaia
T I
TI
Kliuchnikova
Zh I
ZhI
Evstigneeva
M K
MK
Khalilov
E M
EM
D000818:Animals; D001011:Aorta / Q000473:pathology; D001161:Arteriosclerosis / Q000097:blood / Q000473:pathology / Q000517:prevention & control*; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D003314:Corn Oil / Q000008:administration & dosage*; D004032:Diet; D011817:Rabbits; D013997:Time Factors; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D014280:Triglycerides; D003314:Corn Oil; D002784:Cholesterol
Antiaterogennoe deĭstvie kukuruznogo masla pri éksperimental'nom ateroskleroze.