title: Organellar proton-ATPases.
abstract: Proton pumps that belong to the families of F-ATPases and V-ATPases operate without the formation of a phosphorylated intermediate and contain several subunits grouped into distinct catalytic and membrane sectors. Recent studies on the structure and molecular biology of V-ATPases shed light not only on the structure-function relations between the two families, but also on their evolution in all organisms.
authors.affiliation: Roche Institute of Molecular Biology, Nutley, New Jersey.
authors.forename: N
authors.initials: N
authors.lastname: Nelson
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D005075:Biological Evolution; D006801:Humans; D008969:Molecular Sequence Data; D015388:Organelles / Q000201:enzymology*; D017494:Proton Pumps / Q000502:physiology*; D006180:Proton-Translocating ATPases / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D013329:Structure-Activity Relationship
chemical_list: D017494:Proton Pumps; D006180:Proton-Translocating ATPases