Diagnosis and treatment of biomaterial-associated vascular infections.
Management of biomaterial-associated vascular infections requires an understanding of pathogenetic mechanisms, risk factors, and microbiologic characteristics. Staphylococci sp., especially slime-producing strains of S. epidermidis are the prevalent pathogens. Experimental and clinical studies have indicated in situ replacement, particularly with an antibiotic-bonded prosthesis, as effective treatment for infections caused by coagulase-negative staphylococci. When sepsis is a presenting sign, prompt intervention, total excision of the prosthesis, and antibiotic administration are required.
Bandyk
D F
DF
Department of Surgery, University of South Florida College of Medicine, Tampa.
D000818:Animals; D001672:Biocompatible Materials / Q000009:adverse effects*; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D006801:Humans; D016459:Prosthesis-Related Infections / Q000145:classification / Q000175:diagnosis / Q000601:surgery; D012086:Reoperation
D001672:Biocompatible Materials