title: Diagnosis and treatment of biomaterial-associated vascular infections.
abstract: Management of biomaterial-associated vascular infections requires an understanding of pathogenetic mechanisms, risk factors, and microbiologic characteristics. Staphylococci sp., especially slime-producing strains of S. epidermidis are the prevalent pathogens. Experimental and clinical studies have indicated in situ replacement, particularly with an antibiotic-bonded prosthesis, as effective treatment for infections caused by coagulase-negative staphylococci. When sepsis is a presenting sign, prompt intervention, total excision of the prosthesis, and antibiotic administration are required.
authors.affiliation: Department of Surgery, University of South Florida College of Medicine, Tampa.
authors.forename: D F
authors.initials: DF
authors.lastname: Bandyk
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000009:adverse effects*; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D006801:Humans; D016459:Prosthesis-Related Infections / Q000145:classification / Q000175:diagnosis / Q000601:surgery; D012086:Reoperation
chemical_list: D001672:Biocompatible Materials