[Stability and chemosensitivity of Plasmodium falciparum to chloroquine in 1990 and 1991 in Ankazobe, a village in high plateau Madagascar].
The in vivo and in vitro response of Plasmodium falciparum to chloroquine was conducted in Ankazobe, a village located in the high plateau area. These studies confirmed the low level of chloroquine-resistance. The in vivo data indicate the absence of increase resistance during the 2 years study. Chloroquine is still the drug of choice for the treatment of malaria attack in this area.
Ringwald
P
P
Unité de Recherche sur le Paludisme, Institut Pasteur de Madagascar, Antananarivo.
Rabarison
P
P
Raharimalala
L
L
Rason
M D
MD
Lepers
J P
JP
Le Bras
J
J
Roux
J
J
D000818:Animals; D002738:Chloroquine / Q000494:pharmacology* / Q000627:therapeutic use; D004351:Drug Resistance; D006801:Humans; D008270:Madagascar; D016778:Malaria, Falciparum / Q000188:drug therapy / Q000469:parasitology; D010963:Plasmodium falciparum / Q000187:drug effects*
D002738:Chloroquine
Stabilité de la chimiosensibilité de Plasmodium falciparum a la chloroquine en 1990 et 1991 a Ankazobe, village des hauts plateaux malgaches.