MHC antigens and cancer: implications for T-cell surveillance.
Evidence for a direct involvement of cell-mediated immune mechanisms in the control of human tumours remains sketchy. The past year, however, has seen advances in our understanding of the relationship between the immune system and tumour cells, and has given rise to new prospects for immunological treatment and the prevention of cancers.
Browning
M J
MJ
Imperial Cancer Research Fund, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK.
Bodmer
W F
WF
D000951:Antigens, Neoplasm / Q000235:genetics; D016207:Cytokines / Q000502:physiology; D015395:Histocompatibility Antigens Class I / Q000032:analysis*; D000949:Histocompatibility Antigens Class II / Q000032:analysis*; D006801:Humans; D009369:Neoplasms / Q000276:immunology*; D009857:Oncogenes; D013601:T-Lymphocytes / Q000276:immunology*
D000951:Antigens, Neoplasm; D016207:Cytokines; D015395:Histocompatibility Antigens Class I; D000949:Histocompatibility Antigens Class II