POEMS syndrome--a case report.
POEMS syndrome is a multisystem disorder associated with polyneuropathy, organomegaly, endocrinopathy, a monoclonal protein (M-protein), and skin changes. The authors describe a patient with POEMS syndrome who had osteosclerotic myeloma confirmed by open bone biopsy. Magnetic resonance imaging (MRI) showed discrete lesions of low signal intensity in both T1 and T2-weighted images. This patient is now being successfully treated with melphalan and prednisone with much improvement in skin thickening and sensory change in the lower extremities.
Kim
J W
JW
Department of Neurology, College of Medicine, Dong-A University, Korea.
Lee
S K
SK
Ha
K M
KM
Kim
K H
KH
Joh
G Y
GY
Kim
H J
HJ
Yang
S O
SO
Hong
S H
SH
D000328:Adult; D001706:Biopsy; D005272:Femur Neck / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009101:Multiple Myeloma / Q000150:complications / Q000473:pathology; D016878:POEMS Syndrome / Q000150:complications / Q000175:diagnosis*