title: Relations over time between psychiatric and somatic disorders: the Stirling County Study.
abstract: A longitudinal study of a general population in Atlantic Canada provided information on associations between two broad categories of illness: somatic disorders and disorders involving depression and/or anxiety. Prevalence was investigated in a sample of 1,003 adults selected in 1952 and another sample of 1,094 adults selected in 1970. Using a cohort of 618 survivors from the 1952 sample who were followed up in 1968, the authors studied prevalence at the beginning and end of the 16-year period. Incidence was also investigated so that the strength of associations between prior illness of one type and subsequent illness of the other type could be assessed. Data were obtained by interviewing subjects with the same structured schedule at each time of investigation. In prevalence enumerations, psychiatric disorders were found to be significantly associated with somatic disorders. Prior somatic disorder was significantly associated with subsequent incidence of depression and/or anxiety and vice versa. The results did not, however, show one direction of influence ("psyche-to-soma" or "soma-to-psyche") to be markedly stronger than the other. The results mainly support the concept of "generalized vulnerability" and draw attention to the importance of recognizing comorbidity in diagnosis and clinical practice.
authors.affiliation: Psychiatric Epidemiology Unit, Massachusetts General Hospital, Boston 02114.
authors.forename: J M
authors.initials: JM
authors.lastname: Murphy
authors.forename: R R
authors.initials: RR
authors.lastname: Monson
authors.forename: D C
authors.initials: DC
authors.lastname: Olivier
authors.forename: G E
authors.initials: GE
authors.lastname: Zahner
authors.forename: A M
authors.initials: AM
authors.lastname: Sobol
authors.forename: A H
authors.initials: AH
authors.lastname: Leighton
mesh_terms: D000328:Adult; D001008:Anxiety Disorders / Q000150:complications / Q000453:epidemiology*; D002170:Canada / Q000453:epidemiology; D015897:Comorbidity; D003430:Cross-Sectional Studies; D003866:Depressive Disorder / Q000150:complications / Q000453:epidemiology*; D005260:Female; D006304:Health Status; D006306:Health Surveys; D006694:Holistic Health; D006801:Humans; D015994:Incidence; D007406:Interview, Psychological; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D013997:Time Factors