title: [A case of flomoxef-induced pneumonitis].
abstract: We report a case of flomoxef-induced pneumonitis. A 22-year-old man was treated with flomoxef following liver biopsy. A few days later he developed a high fever and severe dyspnea, and his chest X-ray film revealed diffuse reticulo-nodular shadows in both lung fields. We suspected interstitial pneumonitis due to flomoxef, and pulse therapy with methylprednisolone was started. He showed rapid recovery of symptoms and marked regression of pulmonary infiltration in his chest X-ray. Lymphocyte stimulation test was positive to flomoxef, which was compatible with the diagnosis of drug-induced pneumonitis. To our knowledge, there has been no previous case of pulmonary hypersensitivity to flomoxef reported in Japan.
authors.affiliation: First Department of Medicine, Teikyo University School of Medicine, Tokyo.
authors.forename: Y
authors.initials: Y
authors.lastname: Wako
authors.forename: T
authors.initials: T
authors.lastname: Hamauzu
authors.forename: M
authors.initials: M
authors.lastname: Tamura
authors.forename: M
authors.initials: M
authors.lastname: Yokote
authors.forename: M
authors.initials: M
authors.lastname: Yokote
authors.forename: S
authors.initials: S
authors.lastname: Shoji
authors.forename: H
authors.initials: H
authors.lastname: Takikawa
authors.forename: K
authors.initials: K
authors.lastname: Miyake
authors.forename: M
authors.initials: M
authors.lastname: Yamanaka
authors.forename: H
authors.initials: H
authors.lastname: Goto
mesh_terms: D000328:Adult; D001706:Biopsy; D002511:Cephalosporins / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology*; D006801:Humans; D008099:Liver / Q000473:pathology; D008213:Lymphocyte Activation; D008297:Male; D011658:Pulmonary Fibrosis / Q000139:chemically induced*
chemical_list: D002511:Cephalosporins; C045693:flomoxef