False-positive elevation of CA-125 in papillary serous carcinoma of the endometrium treated with postoperative whole abdominal radiation.
Two patients with Stage I papillary serous carcinoma of the endometrium treated with postoperative whole abdominal radiation developed elevated CA-125 levels. In neither patient was evidence of recurrent disease identified. Hepatic veno-occlusive disease, a known complication of whole abdominal radiation and certain chemotherapy regimens, was confirmed by liver biopsy in both cases. CA-125 levels may not be reflective of disease status in this setting.
Rose
P G
PG
Department of Obstetrics and Gynecology, University of Massachusetts Medical Center, Worcester 01655.
Nelson
B E
BE
Reale
F R
FR
D000005:Abdomen / Q000528:radiation effects*; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis*; D001706:Biopsy; D002291:Carcinoma, Papillary / Q000453:epidemiology / Q000276:immunology* / Q000532:radiotherapy*; D016889:Endometrial Neoplasms / Q000453:epidemiology / Q000276:immunology* / Q000532:radiotherapy*; D005189:False Positive Reactions; D005260:Female; D005500:Follow-Up Studies; D006504:Hepatic Veno-Occlusive Disease / Q000175:diagnosis / Q000209:etiology / Q000473:pathology; D006801:Humans; D008099:Liver / Q000473:pathology; D008875:Middle Aged; D011832:Radiation Injuries / Q000150:complications / Q000175:diagnosis / Q000473:pathology
D015295:Antigens, Tumor-Associated, Carbohydrate