title: Use of nitroglycerin ointment to prevent hypertensive response during electroconvulsive therapy--a study of 50 cases.
abstract: Fifty patients of either sex, aged between 20 and 60 years undergoing electroconvulsive therapy were included in our study. Each patient was used as his/her own control. We observed the cardiovascular changes without nitroglycerin ointment in the first sitting and in the next sitting with the application of 2 inches of 2% nitroglycerin ointment 45 min before the electroconvulsive therapy. Arterial blood pressure and heart rate increase during electroconvulsive therapy can be effectively attenuated by application of 2 inches of 2% nitroglycerin ointment 45 min before the electroconvulsive therapy (p < 0.001 and p < 0.01 resp.). This may be especially beneficial for patients who are at increased risk of myocardial ischemia and stroke.
authors.affiliation: Dept of Anaesthesia, Seth G S Medical College and KEM Hospital, Parel, Bombay.
authors.forename: A L
authors.initials: AL
authors.lastname: Parab
authors.forename: L S
authors.initials: LS
authors.lastname: Chaudhari
authors.forename: J
authors.initials: J
authors.lastname: Apte
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D004565:Electroconvulsive Therapy / Q000009:adverse effects*; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D009824:Ointments
chemical_list: D009824:Ointments; D005996:Nitroglycerin