title: Effect of cobra venom factor on experimental infection of mice against Clostridium chauvoei.
abstract: The effect of cobra venom factor (CoVF) treatment was examined to clarify the mechanism of resistance of mice to Clostridium chauvoei infection. In CoVF-treated mice inoculated with spores of C. chauvoei, no death occurred and the organisms in the infected muscle progressively decreased, similar to that of non-treated control mice. These results indicated that C3 did not play a significant role in the resistance of mice against C. chauvoei infection.
authors.affiliation: National Veterinary Assay Laboratory, Tokyo, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Tamura
authors.forename: M
authors.initials: M
authors.lastname: Kijima
authors.forename: S
authors.initials: S
authors.lastname: Suzuki
authors.forename: T
authors.initials: T
authors.lastname: Takahashi
authors.forename: M
authors.initials: M
authors.lastname: Nakamura
mesh_terms: D000818:Animals; D003015:Clostridium Infections / Q000276:immunology / Q000662:veterinary*; D003176:Complement C3 / Q000187:drug effects / Q000276:immunology*; D004546:Elapid Venoms / Q000494:pharmacology*; D005260:Female; D007113:Immunity, Innate / Q000187:drug effects; D051379:Mice / Q000276:immunology*
chemical_list: D003176:Complement C3; D004546:Elapid Venoms; C016310:cobra venom factor