[The effect of chemotherapy on the total unsaturation and composition of plasma phospholipids and erythrocytes in patients with disseminated breast cancer].
The total unsaturation and composition of blood phospholipids were studied in patients with disseminated breast cancer prior to and after chemotherapy. It was shown that the level of double bonds in blood lipids was quite definitely related to the effect of treatment and may have an independent prognostic significance. A correlation was established between the survival of patients and the character of changes in the level of double bonds after chemotherapy. The treatment did not influence the relative content of different fractions and the oxidizability of plasma phospholipids and erythrocytes.
Korman
D B
DB
Potapov
S L
SL
Shamaev
V I
VI
Pal'mina
N P
NP
Burlakova
E B
EB
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000097:blood / Q000188:drug therapy* / Q000401:mortality; D004912:Erythrocytes / Q000737:chemistry / Q000187:drug effects; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D009364:Neoplasm Recurrence, Local / Q000097:blood / Q000188:drug therapy / Q000401:mortality; D010743:Phospholipids / Q000097:blood*; D010949:Plasma / Q000737:chemistry / Q000187:drug effects; D011379:Prognosis; D012074:Remission Induction; D013997:Time Factors
D000970:Antineoplastic Agents; D010743:Phospholipids
Vliianie khimioterapii na summarnuiu nenasyshchennost' i sostav fosfolipidov plazmy i éritrotsitov u bol'nykh rasprostranennym rakom molochnoĭ zhelezy.