title: Balloon valvuloplasty for congenital aortic valve stenosis in an infant and children.
abstract: Percutaneous balloon aortic valvuloplasty (BAV) was performed in 14 patients, including one critically ill infant with congenital valvular aortic stenosis (AS). BAV was effective in 13 patients (except the infant). The peak systolic pressure gradient between the left ventricle (LV) and the ascending aorta decreased from 76.6 +/- 21.6 to 29.5 +/- 15.3 mmHg (P less than 0.001). Follow-up cardiac catheterization was performed for eight patients between 1 and 3 years (1.6 +/- 1.1 years) after BAV. Restenosis was found in only one patient, and the efficacy of BAV continued significantly. Aortic regurgitation developed or increased in severity in 5 of 13 children immediately after BAV. Any other severe complication was not observed. Dilatation by BAV was not sufficient for the infant with critical AS, and acute myocardial infarction (AMI) in the lateral wall of the LV occurred during the BAV procedure. The infant died 3 days after the procedure due to AMI. It was concluded that the retrograde double balloon technique was superior to the retrograde single balloon technique. In two cases, the single balloon technique was ineffective because it was impossible to fix the balloon at the aortic annulus. However, the double balloon technique was effective in every patient. BAV is effective for AS in children, and an optional repeat trial may enable BAV to be the first choice for AS. Although BAV may be effective for neonates and infants with critical AS as an emergency treatment, much attention must be paid during the procedure.
authors.affiliation: Department of Pediatrics, Kurume University, School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Saiki
authors.forename: H
authors.initials: H
authors.lastname: Kato
authors.forename: K
authors.initials: K
authors.lastname: Suzuki
authors.forename: O
authors.initials: O
authors.lastname: Inoue
authors.forename: O
authors.initials: O
authors.lastname: Toyoda
authors.forename: J
authors.initials: J
authors.lastname: Takagi
authors.forename: N
authors.initials: N
authors.lastname: Sato
authors.forename: N
authors.initials: N
authors.lastname: Ohara
authors.forename: T
authors.initials: T
authors.lastname: Akagi
authors.forename: M
authors.initials: M
authors.lastname: Ishii
mesh_terms: D000293:Adolescent; D001022:Aortic Valve Insufficiency / Q000209:etiology; D001024:Aortic Valve Stenosis / Q000151:congenital* / Q000503:physiopathology / Q000628:therapy*; D001794:Blood Pressure; D002404:Catheterization / Q000009:adverse effects / Q000295:instrumentation; D002648:Child; D002675:Child, Preschool; D016638:Critical Illness; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009203:Myocardial Infarction / Q000209:etiology; D016896:Treatment Outcome