title: (+)-4 beta-hydroxyhernandulcin, a new sweet sesquiterpene from the leaves and flowers of Lippia dulcis.
abstract: From the leaves and flowers of Lippia dulcis collected in Panama, a new sweet sesquiterpene identified as (+)-4 beta-hydroxyhernandulcin [2] was isolated, accompanied by (+)-hernandulcin [1], (-)-epihernandulcin [3] (a novel natural product), and 6-methyl-5-hepten-2-one [4]. Acteoside (verbascoside) [5], a known bitter phenylpropanoid glycoside, was isolated from the flowers of L. dulcis. The structure of (+)-4 beta-hydroxyhernandulcin was established by interpretation of its spectral data.
authors.affiliation: Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois, Chicago 60612.
authors.forename: N
authors.initials: N
authors.lastname: Kaneda
authors.forename: I S
authors.initials: IS
authors.lastname: Lee
authors.forename: M P
authors.initials: MP
authors.lastname: Gupta
authors.forename: D D
authors.initials: DD
authors.lastname: Soejarto
authors.forename: A D
authors.initials: AD
authors.lastname: Kinghorn
mesh_terms: D010176:Panama; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000032:analysis / Q000302:isolation & purification*
chemical_list: D012717:Sesquiterpenes; C077625:4-hydroxyhernandulcin