title: Right ventricular systolic time intervals determined by means of a pulmonary artery catheter.
abstract: OBJECTIVE
  To evaluate the right ventricular systolic time interval as an index of right ventricular function and also to ascertain whether the right ventricular ejection fraction may be determined by means of a conventional pulmonary artery catheter.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  Intensive care unit.
  
  
  METHODS
  Eight, consecutive critically ill adult patients.
  
  
  METHODS
  Simultaneous blind measurements, performed by two investigators, of the right ventricular systolic time interval and right ventricular ejection fraction, determined by means of a pulmonary artery catheter. Two studies, separated by an interval of 24 hrs, per patient. Linear regression analysis. Multiple regression test.
  
  
  RESULTS
  Of the 16 studies performed, two determinations of right ventricular systolic time intervals were technically inadequate. In the remaining 14 valid studies, we found one close linear correlation between the right ventricular ejection fraction and the preejection period/ejection time quotient measured using the simultaneous display of the electrocardiogram (EKG) and pulmonary arterial pressure curve (r2 = .90, p < .001, right ventricular ejection fraction = 68.96-60.59 x [right ventricular preejection period/right ventricular ejection time]). The method proved to be simple, very accurate, with little interobserver variation (8.09 +/- 10.6% interobserver variation for right ventricular preejection period/right ventricular ejection time) and provided adequate information regarding situations in which the performance of the right ventricle is modified in a given patient. The right ventricular preejection period/right ventricular ejection time quotient was the only variable that displayed a significant relationship with the right ventricular ejection fraction in the multivariate analysis (p < .001).
  
  
  CONCLUSIONS
  Right ventricular systolic time intervals, measured using the simultaneous display of the pulmonary artery catheter curve and EKG, provide adequate information regarding right ventricle performance in critically ill patients. The close linear correlation between the right ventricular preejection period/right ventricular ejection time quotient and the right ventricular ejection fraction enables the investigator to estimate, with a high degree of accuracy, the right ventricular ejection fraction and the values derived from the preload of the right ventricle, without the need for a modified pulmonary artery catheter.
authors.affiliation: Servicio de Medicina Intensiva, Hospital General Gregorio Marañón, Universidad Complutense, Madrid, Spain.
authors.forename: J E
authors.initials: JE
authors.lastname: Guerrero
authors.forename: J
authors.initials: J
authors.lastname: Muñoz
authors.forename: B
authors.initials: B
authors.lastname: De La Calle
authors.forename: R
authors.initials: R
authors.lastname: Valero
authors.forename: M T
authors.initials: MT
authors.lastname: Alberca
mesh_terms: D000368:Aged; D002407:Catheterization, Swan-Ganz / Q000295:instrumentation / Q000379:methods / Q000592:standards*; D016638:Critical Illness; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007362:Intensive Care Units; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods / Q000592:standards*; D011446:Prospective Studies; D015203:Reproducibility of Results; D013318:Stroke Volume; D013599:Systole; D013815:Thermodilution; D013997:Time Factors; D016278:Ventricular Function, Right / Q000502:physiology*