[Genetic analysis of various behavioral and physiologic characteristics in hybrids between hypertensive and normotensive rats. Analysis of correlational connections].
Hereditary links between different behavioral and physiological traits were studied in rat strains SHR, WKY and their hybrids F1 and F2 by analysis of correlations in segregating and nonsegregating gene-rations. Genetic correlation of arterial pressure with body mass, intake of KC1 solution and the ability to avoidance learning (directed positively) and with characteristics of exploratory activity (directed negatively) was shown. These traits seemed to be possible genetic markers of arterial hypertension. Genetical correlates of the ability to elaborate active avoidance conditional reaction (arterial pressure and pain sensitivity) testify to relief of active avoidance learning in animals with inherited active-defensive type of behaviour, manifested by predisposition to pressor reactions and by suppressed emotional reactions to pain stimulation. Frequency in intertrial crossings during avoidance training displays positive correlation with characteristics of exploratory behaviour. Positive correlation between different characteristics of exploratory activity was established both in segregating and nonsegregating generations.
Bachmanov
A A
AA
Dmitriev
Iu S
IuS
D000818:Animals; D001362:Avoidance Learning / Q000502:physiology; D001522:Behavior, Animal / Q000502:physiology*; D001794:Blood Pressure / Q000235:genetics; D001835:Body Weight / Q000187:drug effects; D002755:Choice Behavior / Q000502:physiology; D003433:Crosses, Genetic; D005260:Female; D008040:Genetic Linkage / Q000235:genetics; D005819:Genetic Markers / Q000235:genetics; D006824:Hybridization, Genetic; D006973:Hypertension / Q000235:genetics*; D008297:Male; D009949:Orientation / Q000502:physiology; D011189:Potassium Chloride / Q000008:administration & dosage; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY; D014828:Vocalization, Animal / Q000502:physiology
D005819:Genetic Markers; D011189:Potassium Chloride
Geneticheskiĭ analiz nekotorykh povedencheskikh i fizioiogicheskikh priznakov u gibridov gipertenzivenykh i normotenzivnykh krys. Analiz korreliatsionnykh sviazeĭ.