title: The study of the cultivation of Chinese hamster ovary and Bowes cell lines with poly(organophosphazene) membranes.
abstract: Sixteen poly(organophosphazenes) were prepared by reaction between polydichlorophosphazene (NPCl2)n and nucleophilic reagents such as phenoxides and amino compounds. Adhesive and colony formation percent were investigated using V-79 Chinese hamster cells on poly(organophosphazene) films. It was found that [NP(OC6H5)2-x(NHBu-n)x]n (x = 0.2, 1.8) gave the best percent adhesiveness. This value was similar to that of Falcon. On the other hand, [NP(OC6H5)-(NHBu-n)]n film showed best colony percent formation. This was of a higher value than that of Falcon. The [NP(OC6H5)2]n properties were poor for cultivation of useful Bowes and chinese hamster ovary cell lines in comparison with Cytodex III.
authors.affiliation: Department of Applied Chemistry, Faculty of Engineering, Nagoya University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kajiwara
mesh_terms: D000818:Animals; D016466:CHO Cells / Q000166:cytology* / Q000187:drug effects; D002448:Cell Adhesion / Q000502:physiology; D002460:Cell Line; D003114:Colony-Forming Units Assay; D006224:Cricetinae; D003412:Cricetulus; D005260:Female; D008168:Lung / Q000166:cytology / Q000187:drug effects; D008567:Membranes, Artificial; D008863:Microspheres; D009943:Organophosphorus Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D011108:Polymers / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D008567:Membranes, Artificial; D009943:Organophosphorus Compounds; D011108:Polymers