title: [Effects of prostaglandin E1 analogs on the cervix--observations with vaginal sonography].
abstract: In this study participated 17 patients, in whose pregnancies not viable malformations or intrauterine deaths were diagnosed. The termination of the pregnancies was done with PG-E-1 suppositories Gemeprost (Cergem) 1 mg. Collectively the patients received 3 Cergem suppositories applicated all 3 hours. Before beginning therapy and every 4-6 hours a vaginosonography was done. The cervical changes under the influence of Gemeprost were documented vaginosonographically. The measurements before Gemeprost treatment showed an average cervical length of 44.2 +/- 6.3 mm, a width of 29.5 +/- 1.7 mm and an internal os of 2.5 +/- 0.5 mm. The results of the second ultrasound showed a length of 30.6 +/- 4.1 mm, a width of 32.3 +/- 2.5 mm and an internal os of 7.0 +/- 3.0 mm. The last measurements (ca. 107 minutes before abortion) showed a remaining of cervical length of 15.2 +/- 4.5 mm, a width of 41.5 +/- 4.6 mm, an internal os of 19.2 +/- 4.1 mm and the amniotic membranes bulged into the cervical channel.
authors.affiliation: I. Univ.-Frauenklinik, Wien.
authors.forename: W
authors.initials: W
authors.lastname: Eppel
authors.forename: B
authors.initials: B
authors.lastname: Schurz
authors.forename: P
authors.initials: P
authors.lastname: Frigo
authors.forename: E
authors.initials: E
authors.lastname: Reinold
mesh_terms: D000020:Abortifacient Agents, Nonsteroidal / Q000008:administration & dosage*; D000527:Alprostadil / Q000008:administration & dosage / Q000031:analogs & derivatives*; D002584:Cervix Uteri / Q000000981:diagnostic imaging / Q000187:drug effects*; D000013:Congenital Abnormalities / Q000000981:diagnostic imaging; D005260:Female; D005313:Fetal Death; D006801:Humans; D007231:Infant, Newborn; D007751:Labor, Induced / Q000379:methods*; D011247:Pregnancy; D016216:Ultrasonography, Prenatal
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; C021182:gemeprost; D000527:Alprostadil
vernacular_title: Der Einfluss von Prostaglandin-E-1 Analoga auf die Zervix--Beobachtungen mit der Vaginosonographie.