Cell adhesion molecules, second messengers and axonal growth.
Recent studies on NCAM-related molecules suggest that individual cell adhesion molecules might function to both promote axonal growth during development and maintain synaptic structure in the adult. Evidence that differential alternative splicing contributes to this apparent bifunctionality of cell adhesion molecules is discussed.
Doherty
P
P
Department of Experimental Pathology, United Medical School, Guy's Hospital, London, UK.
Walsh
F S
FS
D000818:Animals; D001369:Axons / Q000502:physiology*; D015816:Cell Adhesion Molecules, Neuronal / Q000378:metabolism*; D006801:Humans; D015290:Second Messenger Systems / Q000502:physiology*
D015816:Cell Adhesion Molecules, Neuronal