Sepsis.
Septic shock is associated with a very high mortality in elderly patients. This is likely due to the age-related anatomic and physiologic changes and the presence of comorbid diseases. Medical management of patients with septic shock consists of antibiotics, fluids, vasopressors, and careful monitoring. Judicious use of antiendotoxin monoclonal antibodies may be a beneficial adjunctive therapy.
Bender
B S
BS
University of Florida College of Medicine, Gainesville.
D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D016470:Bacteremia / Q000401:mortality / Q000503:physiopathology; D005334:Fever / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D012772:Shock, Septic / Q000382:microbiology / Q000401:mortality / Q000503:physiopathology / Q000628:therapy
D000900:Anti-Bacterial Agents; D000911:Antibodies, Monoclonal