Costimulation of T-cell growth.
The specificity of T-cell recognition is dictated by the interaction of the T-cell receptor with MHC-peptide complexes. The biological consequences of such recognition is determined, however, by costimulatory pathway(s). Recent studies have led to the identification of receptor-counter-receptor pairs that may regulate T-cell costimulation.
Liu
Y
Y
Department of Pathology, New York University Medical Center, New York 10016.
Linsley
P S
PS
D000818:Animals; D015815:Cell Adhesion Molecules / Q000502:physiology; D007108:Immune Tolerance / Q000502:physiology; D008213:Lymphocyte Activation / Q000502:physiology*; D011948:Receptors, Antigen, T-Cell / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*
D015815:Cell Adhesion Molecules; D011948:Receptors, Antigen, T-Cell