title: [Features of metabolic disorders in the liver during morphine poisoning of various duration].
abstract: Administration of morphine into rats at a dose of 30 mg/kg within 6 days led to a decrease in total rate of tRNA aminoacylation in liver tissue. Content of lactate, pyruvate, malate and alpha-ketoglutarate was decreased within 6 days-long course of morphine administration, while content of lactate was only altered after 5 weeks of the intoxication. Adaptation reactions appear to be increased with time in long-term intoxication with morphine.
authors.forename: M F
authors.initials: MF
authors.lastname: Gulyĭ
authors.forename: V N
authors.initials: VN
authors.lastname: Sinitskiĭ
authors.forename: N A
authors.initials: NA
authors.lastname: Stogniĭ
authors.forename: V V
authors.initials: VV
authors.lastname: Sushkova
authors.forename: N V
authors.initials: NV
authors.lastname: Silonova
authors.forename: N F
authors.initials: NF
authors.lastname: Shevtsova
authors.forename: N N
authors.initials: NN
authors.lastname: Kas'ianova
mesh_terms: D000818:Animals; D002952:Citric Acid Cycle; D004734:Energy Metabolism; D006019:Glycolysis; D008099:Liver / Q000378:metabolism*; D008297:Male; D009020:Morphine / Q000506:poisoning*; D014176:Protein Biosynthesis; D012346:RNA, Transfer, Amino Acyl / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar
chemical_list: D012346:RNA, Transfer, Amino Acyl; D009020:Morphine
vernacular_title: Osobennosti metabolicheskikh narusheniĭ v pechenii pri morfinnoĭ intoksikatsii razlichnoĭ dlitel'nosti.