[Metabolic effects of phosphate receptors stimulating the ileal transport of calcium].
Several compounds, either metabolizable such as sorbitol and creatine or unmetabolizable such as L-xylose or ethyl-ethanolamine, increase ileal calcium transport, similarly to the well documented effect of lactose. These compounds increase the duration time but not the rate of calcium transport. They have no specific effect on intestinal calcium absorption but they prolong the presence of soluble calcium in the ileal loop, thus allowing the calcium absorption. This stimulating effect of these compounds on mineral absorption is associated with an increase of ileal mucosal ATP content.
Fournier
P
P
Métabolisme minéral des Mammifères (E.P.H.E.), Faculté de Pharmacie, Chatenay-Malabry.
Tardivel
S
S
Lacour
B
B
Dupuis
Y
Y
D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D002118:Calcium / Q000493:pharmacokinetics*; D003401:Creatine / Q000494:pharmacology*; D004983:Ethanolamines / Q000494:pharmacology; D007082:Ileum / Q000378:metabolism*; D007408:Intestinal Absorption; D010710:Phosphates / Q000378:metabolism*; D051381:Rats; D013012:Sorbitol / Q000494:pharmacology*; D014994:Xylose / Q000494:pharmacology
D004983:Ethanolamines; D010710:Phosphates; D013012:Sorbitol; D014994:Xylose; D003401:Creatine; D002118:Calcium
Effets métaboliques d'accepteurs de phosphate stimulant le transport iléal du calcium.