[Changes in the concentration of beta-endorphin in the cerebrospinal fluid due to morphine analgesia in incurable oncologic patients].
Thirty cancer patients, clinical group IV, have been examined. It has been established that a persistent pain syndrome leads to lowering in beta-endorphin liquor level. Morphine analgesia is followed by beta-endorphin level elevation which directly depends on pain intensity and analgesia efficacy. Determination of changes in beta-endorphin liquor level may serve as a criterion of analgesia efficacy.
Isakova
M E
ME
Pavlova
Z V
ZV
Bassalyk
L S
LS
Kushlinskiĭ
N E
NE
D015360:Analgesia, Epidural; D005260:Female; D006801:Humans; D008297:Male; D009020:Morphine; D009369:Neoplasms / Q000503:physiopathology*; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D001615:beta-Endorphin / Q000134:cerebrospinal fluid*
D001615:beta-Endorphin; D009020:Morphine
Izmeneniia kontsentratsiĭ beta-éndorfina v likvore pod vliianiem spinal'noĭ analgezii morfinom u inkurabel'nykh onkologicheskikh bol'nykh.