Serotoninergic reinnervation of regenerating tentacular sensory organs in a pulmonate snail, Cryptomphalus aspersa.
Several ontogenetic studies performed in different species suggest a developmental role for 5-HT neurons. The 5-HT system interconnecting the CNS and the tentacular sensory organs in pulmonates is a suitable model for studying the postulated developmental role of 5-HT neurons. In this paper we describe the behavior of the 5-HT fibers during the early stages of blastema reinnervation, primordium formation and differentiation of regenerating tentacular sensory organs in the pulmonate snail Cryptomphalus aspersa. Our results show that the regeneration process allows the development of a normal pattern of 5-HT innervation of the regenerated sensory organs and suggest that 5-HT could be involved in reciprocal developmental interactions with regenerating tentacular tissues.
Flores
V
V
Instituto de Biología Celular, Facultad de Medicina, Universidad de Buenos Aires, Capital Federal, Argentina.
Brusco
A
A
Scicolone
G
G
Saavedra
J P
JP
D000818:Animals; D007150:Immunohistochemistry; D009412:Nerve Fibers / Q000502:physiology; D009416:Nerve Regeneration / Q000502:physiology*; D009799:Ocular Physiological Phenomena; D012038:Regeneration; D012679:Sense Organs / Q000502:physiology*; D012701:Serotonin / Q000502:physiology*; D012908:Snails / Q000502:physiology*; D014945:Wound Healing / Q000502:physiology
D012701:Serotonin