Neuronal polarity.
The axonal and somatodendritic domains of neurons differ in their cytoskeletal and membrane composition, complement of organelles, and capacity for macromolecular synthesis. Recently there has been progress in elucidating the cellular mechanisms that underlie the establishment and maintenance of neuronal polarity, including microtubule organization and the sorting, transport, and anchoring of membrane proteins.
Craig
A M
AM
Department of Neuroscience, University of Virginia School of Medicine, Charlottesville 22908.
Jareb
M
M
Banker
G
G
D000818:Animals; D003599:Cytoskeleton / Q000378:metabolism; D006801:Humans; D009419:Nerve Tissue Proteins / Q000378:metabolism; D009474:Neurons / Q000737:chemistry / Q000502:physiology*
D009419:Nerve Tissue Proteins