[Structure of macrocyclic K+, Rb+-complexon of meso-valinomycin monohydrate, cyclo[-(D-Val-Hyi-Val-D-Hyi)3-].H2O, in a crystalline complex with dioxane by x-ray structural data].
The crystal structure of a valinomycin analogue, cyclo[-(D-Val-Hyi-Val-D-Hyi)3-]x(C60H102N6O18) crystallized with dioxane and water molecules, has been solved by X-ray direct methods. The conformation found is analogous to one established for free meso-valinomycin crystallized from other organic solvents. It is characterized by a centrosymmetric bracelet form, stabilized by six intramolecular 4----1 type hydrogen bonds between amide N-H and C = O groups. One water molecule is fixed asymmetrically by hydrogen bonds in the internal negatively charged cavity of the complexon. The meso-valinomycin molecule "bracelets" in the crystal form stacks alternatively with dioxane molecules.
Pletnev
V Z
VZ
Medical Foundation of Buffalo, N.Y. 14203-1196.
Tsygannik
I N
IN
Fonarev
Iu D
IuD
Ivanov
V T
VT
Lengs
D A
DA
Grokhul'skiĭ
P
P
Dukes
V L
VL
D002414:Cations, Monovalent; D004146:Dioxanes / Q000737:chemistry*; D015394:Molecular Structure; D011188:Potassium / Q000737:chemistry*; D012413:Rubidium / Q000737:chemistry*; D014634:Valinomycin / Q000031:analogs & derivatives* / Q000737:chemistry*; D014961:X-Ray Diffraction
D002414:Cations, Monovalent; D004146:Dioxanes; C077296:dodeca-valinomycin; C077027:octa-valinomycin; D014634:Valinomycin; C025223:1,4-dioxane; D012413:Rubidium; D011188:Potassium
Struktura makrotsiklicheskogo K+, Rb+-kompleksona mezo-valinomitsina- monogidrata, cyclo]-(D-Val-Hyi-Val-D-Hyi)3-].H2O, v kristallicheskom komplekse s dioksanom po dannym rentgenostrukturnogo analiza.