[Quantitative analysis of compound injection of aminopyrine by dual-wavelength linear regression spectrophotometry].
A dual-wavelength linear regression spectrophotometry has been introduced and evaluated. Depending on a group of standard mixture solutions the optimal wavelengths and calibration curve can be determined simultaneously by linear regression method. The deviation of absorption resulting from molecular interaction can be calibrated by this method and the results are more accurate. The validity of this method has been confirmed through its use in the analysis of compound injection of antipyrine with satisfactory recoveries. Results obtained by Kalman filtering (KF), partial least squares (PLS) and target factor analysis (TFA) are also given.
Xiang
B R
BR
Department of Pharmaceutical Analysis, China Pharmaceutical University, Nanjing.
Zhang
Z J
ZJ
Dai
J P
JP
An
D K
DK
D000632:Aminopyrine / Q000032:analysis*; D000983:Antipyrine / Q000032:analysis; D001462:Barbital / Q000032:analysis; D004338:Drug Combinations; D007267:Injections; D013053:Spectrophotometry / Q000379:methods
D004338:Drug Combinations; D000632:Aminopyrine; D001462:Barbital; D000983:Antipyrine