title: Severe exacerbation of chronic active hepatitis B during interferon alpha therapy.
abstract: The case of a 52-year-old male with chronic active type B hepatitis in whom severe exacerbation of liver disease was associated with interferon alpha treatment is described. It seems that patients with very active forms of chronic hepatitis B may experience severe and symptomatic exacerbation of liver disease during interferon treatment.
authors.affiliation: Department of Immunopathology, Institute of Infectious and Parasitic Diseases, Warsaw, Poland.
authors.forename: T
authors.initials: T
authors.lastname: Laskus
authors.forename: M
authors.initials: M
authors.lastname: Radkowski
authors.forename: J
authors.initials: J
authors.lastname: Slusarczyk
authors.forename: J
authors.initials: J
authors.lastname: Cianciara
mesh_terms: D006509:Hepatitis B / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006521:Hepatitis, Chronic / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D016898:Interferon-alpha / Q000009:adverse effects* / Q000627:therapeutic use; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged
chemical_list: D016898:Interferon-alpha