Ca(2+)-mediated interaction between negatively charged and neutral liposomes.
In the present work it is shown that large unilamellar lecithin/cholesterol liposomes are able to sequester small negatively charged liposomes in the presence of divalent cations. Evidence is presented suggesting that the sequestration occurs via the formation of membrane invaginations transformed further into intraliposomal vesicles.
Budker
V G
VG
Institute of Bioorganic Chemistry, Siberian Division of the Russian Academy of Sciences, Novosibirsk.
Kiseleva
H V
HV
Serebryakova
M V
MV
Sokoloff
A V
AV
D002118:Calcium / Q000502:physiology*; D004492:Edetic Acid / Q000494:pharmacology; D008081:Liposomes / Q000378:metabolism*
D008081:Liposomes; D004492:Edetic Acid; D002118:Calcium