Adrenal suppression with intranasal betamethasone drops.
Intranasal betamethasone sodium phosphate drops (Betnesol) are frequently used to relieve nasal congestion due to polyposis. We report a case of significant hypothalamic-pituitary-adrenal suppression secondary to the long-term use of intranasal betamethasone drops. This case emphasizes that the topical application of potent corticosteroids may produce systemic effects.
Flynn
M D
MD
Department of Medicine, Royal Devon and Exeter Hospital.
Beasley
P
P
Tooke
J E
JE
D000281:Administration, Intranasal; D000309:Adrenal Insufficiency / Q000139:chemically induced*; D000368:Aged; D001623:Betamethasone / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D007024:Hypotension, Orthostatic / Q000139:chemically induced; D008297:Male; D009298:Nasal Polyps / Q000188:drug therapy
C028994:betamethasone sodium phosphate; D001623:Betamethasone