title: Recombinant erythropoietin as treatment for the late hyporegenerative anemia of Rh hemolytic disease.
abstract: Infants with Rh hemolytic disease can develop a "late" anemia characterized by low serum concentrations of erythropoietin but erythroid progenitors that remain highly erythropoietin-responsive. Erythropoietin administration was evaluated in two patients as an alternative to transfusion. Reticulocyte counts increased after 5 days of treatment, and hematocrits increased after 10 days. Neither patient received erythrocyte transfusions following erythropoietin therapy.
authors.affiliation: Division of Human Development and Aging, University of Utah School of Medicine, Salt Lake City.
authors.forename: R K
authors.initials: RK
authors.lastname: Ohls
authors.forename: P E
authors.initials: PE
authors.lastname: Wirkus
authors.forename: R D
authors.initials: RD
authors.lastname: Christensen
mesh_terms: D000743:Anemia, Hemolytic / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D001856:Bone Marrow Examination; D004921:Erythropoietin / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D008297:Male; D011994:Recombinant Proteins / Q000627:therapeutic use; D012203:Rh Isoimmunization / Q000097:blood / Q000150:complications*
chemical_list: D011994:Recombinant Proteins; D004921:Erythropoietin