[Antioxidant effect of dimethyl sulfoxide in acute liver injury by carbon tetrachloride].
After subcutaneous administration of dimethyl sulfoxide into rats with toxic, tetrachloromethane-produced impairment of liver tissue, lipid peroxidation was effectively inhibited in hepatocytes and the state of anti-oxidation system was improved. Antioxidative properties of dimethyl sulfoxide were shown also in vitro.
Gonskiĭ
Ia I
IaI
Korda
M M
MM
Klishch
I N
IN
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology* / Q000627:therapeutic use; D002252:Carbon Tetrachloride Poisoning / Q000188:drug therapy*; D004121:Dimethyl Sulfoxide / Q000494:pharmacology* / Q000627:therapeutic use; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D008297:Male; D051381:Rats
D000975:Antioxidants; D004121:Dimethyl Sulfoxide
Antiokislitel'noe deĭstvie dimtilsul'foksida pri ostrom porazhenii pecheni tetrakhlormetanom.