Electrostatic spraying of DNA molecules for investigation by scanning tunneling microscopy.
We have investigated electrostatic spraying of DNA onto gold surfaces as an alternative sample-preparation technique for STM studies. Preliminary results show that a higher distribution of isolated strands as well as well ordered aggregates can be obtained with this technique when compared with electrodeposition or drop evaporation. In many places, the well ordered aggregates were found to cleave in a direction perpendicular to their length after repeated scanning in the same direction.
Thundat
T
T
Oak Ridge National Laboratory, TN 37831.
Warmack
R J
RJ
Allison
D P
DP
Ferrell
T L
TL
D004247:DNA / Q000737:chemistry / Q000648:ultrastructure*; D004563:Electrochemistry; D016252:Microscopy, Scanning Tunneling / Q000379:methods*; D010957:Plasmids; D013048:Specimen Handling
D004247:DNA