title: An antidepressant principle of Lobelia inflata L. (Campanulaceae).
abstract: A crude methanolic extract of the leaves of Lobelia inflata exhibited antidepressant activity in mice. The extract was fractionated, monitored by the activity, to give beta-amyrin palmitate as an active component.
authors.affiliation: Pharmaceutical Institute, Tohoku University, Sendai, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Subarnas
authors.forename: Y
authors.initials: Y
authors.lastname: Oshima
authors.lastname: Sidik
authors.forename: Y
authors.initials: Y
authors.lastname: Ohizumi
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000302:isolation & purification* / Q000494:pharmacology; D007099:Imipramine / Q000494:pharmacology; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009828:Oleanolic Acid / Q000031:analogs & derivatives; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D014315:Triterpenes / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000928:Antidepressive Agents; D010936:Plant Extracts; D014315:Triterpenes; D009828:Oleanolic Acid; C036380:beta-amyrin; D007099:Imipramine