Structure and biological effects of lipid modifications on proteins.
Both the prevalence of lipid modifications of proteins and their importance for protein function and cellular localization have been widely observed. The advances made during the past year in defining the enzymology of lipid addition and in understanding the biological consequences of these modifications on protein function are discussed.
Chow
M
M
Massachusetts Institute of Technology, Cambridge.
Der
C J
CJ
Buss
J E
JE
D000217:Acyltransferases / Q000378:metabolism; D000818:Animals; D006801:Humans; D008055:Lipids / Q000096:biosynthesis / Q000502:physiology*; D010743:Phospholipids / Q000378:metabolism; D017368:Protein Prenylation / Q000502:physiology; D011499:Protein Processing, Post-Translational / Q000502:physiology*; D011506:Proteins / Q000378:metabolism*
D008055:Lipids; D010743:Phospholipids; D011506:Proteins; D000217:Acyltransferases; C050480:glycylpeptide N-tetradecanoyltransferase