title: Low contrast visual acuity changes in human immuno-deficiency virus (HIV) infection.
abstract: A pilot study of low contrast visual acuity testing using Regan Charts has been undertaken in 34 patients seropositive for Human Immuno-Deficiency Virus and 20 normal control subjects. Low contrast visual acuities of the HIV (+) patients both with and without HIV retinopathy were found to be significantly lower than the age-matched controls (p < 0.01). This finding is probably attributable to pathology related to HIV in the visual pathways/Central Nervous System. Lowest contrast Chart (Chart C) was found to be a useful diagnostic tool for HIV retinopathy and presumed neuropathy.
authors.affiliation: Royal Infirmary of Edinburgh, Scotland.
authors.forename: E
authors.initials: E
authors.lastname: Mutlukan
authors.forename: B
authors.initials: B
authors.lastname: Dhillon
authors.forename: P
authors.initials: P
authors.lastname: Aspinall
authors.forename: J F
authors.initials: JF
authors.lastname: Cullen
mesh_terms: D000328:Adult; D015350:Contrast Sensitivity / Q000502:physiology*; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D008297:Male; D010865:Pilot Projects; D012164:Retinal Diseases / Q000175:diagnosis / Q000503:physiopathology*; D014787:Vision Tests / Q000379:methods