Dinucleotide repeat (GT)n markers on chromosome 21.
To further develop the linkage map of human chromosome 21 (HC21), we have concentrated on identifying highly polymorphic markers based on dinucleotide repeat sequences such as (GT)n, as these are often highly polymorphic, are widespread throughout the human genome, and can be rapidly analyzed by the polymerase chain reaction. We report here nine (GT)n polymorphic markers from HC21.
Warren
A C
AC
Center for Medical Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.
McInnis
M G
MG
Blaschak
J
J
Kaliatsidaki
M
M
Petersen
M B
MB
Chakravarti
A
A
Antonarakis
S E
SE
D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D002891:Chromosomes, Human, Pair 21; D004247:DNA; D005819:Genetic Markers; D006801:Humans; D006822:Hybrid Cells; D051379:Mice; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D012091:Repetitive Sequences, Nucleic Acid
D005819:Genetic Markers; D004247:DNA