title: Observations on production of hemolysin, heat-labile enterotoxin and antimicrobial drug resistance among enterotoxigenic Escherichia coli from pigs.
abstract: A total of 52 isolates of Escherichia coli belonging to enterotoxigenic serotypes from piglets with diarrhea were examined for hemolysis, production of cholera-like enterotoxin (LT) and susceptibility to 10 antimicrobial drugs. A strong association between production of LT and hemolysis was seen. Ninety percent of 29 hemolylic isolates were LT+ whereas 100% of 23 nonhemolytic isolates were LT- in a commercial latex agglutination assay. Antimicrobial susceptibility tests employing disc diffusion showed that resistance to trimethoprim-sulfamethoxazole (TMS), neomycin and tetracycline was significantly less among LT+ isolates compared to LT- ones. Enrofloxacin was the only antimicrobial drug to which all the 52 isolates were susceptible.
authors.affiliation: Department of Pathology and Microbiology, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, Canada.
authors.forename: H
authors.initials: H
authors.lastname: Hariharan
authors.forename: S
authors.initials: S
authors.lastname: Heaney
authors.forename: J
authors.initials: J
authors.lastname: Bryenton
authors.forename: J
authors.initials: J
authors.lastname: Daley
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000096:biosynthesis*; D001427:Bacterial Toxins / Q000096:biosynthesis*; D003967:Diarrhea / Q000662:veterinary; D004768:Enterotoxins / Q000096:biosynthesis*; D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism*; D004927:Escherichia coli Infections / Q000662:veterinary; D029968:Escherichia coli Proteins; D006460:Hemolysin Proteins; D006462:Hemolytic Plaque Technique / Q000662:veterinary; D008826:Microbial Sensitivity Tests / Q000662:veterinary; D013552:Swine / Q000382:microbiology*; D013553:Swine Diseases / Q000382:microbiology
chemical_list: D001426:Bacterial Proteins; D001427:Bacterial Toxins; D004768:Enterotoxins; D029968:Escherichia coli Proteins; D006460:Hemolysin Proteins; C036507:Hlya protein, E coli; C027538:heat-labile enterotoxin, E coli