title: [Atherogenesis and serum levels of apolipoprotein E].
abstract: Serum apolipoprotein (apo) E levels and their relationship with age were examined in different age groups of healthy individuals of both sexes in a Lithuanian population. The serum concentrations of apo E in patients after coronary bypass were measured and patients suffered from diabetes mellitus were also examined. The mean levels of apo E were found to be higher in healthy males than those in healthy females only in young age. Serum apo E levels were inversely associated with age (P < 0.05). Apo E levels were significantly higher in males over 45 years of age who suffered from coronary atherosclerosis and in males under 45 who had diabetes mellitus (types I and II) than those in healthy individuals (P < 0.05). There was an insignificant difference in apo E levels among healthy and diabetic females (P < 0.05). The findings demonstrated the association of increased apo E levels with atherogenesis.
authors.forename: D V
authors.initials: DV
authors.lastname: Stakishaĭtis
authors.forename: S M
authors.initials: SM
authors.lastname: Ianchauskene
authors.forename: L I
authors.initials: LI
authors.lastname: Ivashkiavichene
authors.forename: R A
authors.initials: RA
authors.lastname: Priaĭksha
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001057:Apolipoproteins E / Q000097:blood*; D001161:Arteriosclerosis / Q000209:etiology*; D003327:Coronary Disease / Q000097:blood / Q000209:etiology; D003922:Diabetes Mellitus, Type 1 / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D012737:Sex Factors
chemical_list: D001057:Apolipoproteins E
vernacular_title: Aterogenez i soderzhanie apolipoproteina E v syvorotke krovi.