Long term treatment of chronic Lyme arthritis with benzathine penicillin.
The cases are reported of two patients with chronic Lyme arthritis resistant to the recommended antibiotic regimens who were cured by long term treatment with benzathine penicillin. It is suggested that the sustained therapeutic levels of penicillin were effective either by the inhibition of germ replication or by lysis of the spirochaetes when they were leaving their sanctuaries.
Cimmino
M A
MA
Dipartimento di Medicina Interna, Università di Genova, Genoa, Italy.
Accardo
S
S
D000328:Adult; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008193:Lyme Disease / Q000188:drug therapy*; D010401:Penicillin G Benzathine / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors
D010401:Penicillin G Benzathine