Primary cutaneous B-cell lymphoma. Diagnosis, treatment, and prognosis.
BACKGROUND
An elderly woman with B-cell lymphoma confined to the skin of the lower extremity was treated with combination chemotherapy and radiation therapy. She relapsed with new skin lesions outside the original radiation port that responded to additional radiation therapy and remains in remission 12 months after her last treatment.


OBJECTIVE
This article investigates the diagnosis, treatment, and prognosis of primary cutaneous B-cell lymphoma.


METHODS
The relevant literature was researched through computer data bases and bibliographies.


RESULTS
Patients who present with localized lesions of primary cutaneous B-cell lymphoma have a favorable prognosis regardless of the type of therapy, although relapses may occur in the absence of systemic disease.


CONCLUSIONS
We advocate the use of local therapies as initial treatment in patients with localized primary cutaneous B-cell lymphoma.
Watsky
K L
KL
Department of Dermatology, Yale University School of Medicine, New Haven, CT.
Longley
B J
BJ
Dvoretzky
I
I
D000368:Aged; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D011379:Prognosis; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy