Seizure with hyponatremia in a child prescribed desmopressin for nocturnal enuresis.
We report a case of hyponatremia associated with a grand mal seizure in a 28 month-old child after intra-nasal desmopressin administration for high fluid intake with nocturnal enuresis. In view of the temporary symptomatic action and the seriousness of certain side-effects of desmopressin we recommend that desmopressin be used with caution in childhood enuresis.
Yaouyanc
G
G
Department of Medicine, Hôpital du Blanc, France.
Jonville
A P
AP
Yaouyanc-Lapalle
H
H
Barbier
P
P
Dutertre
J P
JP
Autret
E
E
D000281:Administration, Intranasal; D000336:Aerosols; D002675:Child, Preschool; D003894:Deamino Arginine Vasopressin / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D004326:Drinking; D004775:Enuresis / Q000188:drug therapy*; D004830:Epilepsy, Tonic-Clonic / Q000139:chemically induced*; D006801:Humans; D007010:Hyponatremia / Q000139:chemically induced*; D008297:Male; D014869:Water Intoxication / Q000139:chemically induced*
D000336:Aerosols; D003894:Deamino Arginine Vasopressin