Impact of imipenem/cilastatin on cyclosporine metabolism and excretion.
Mraz
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Institute for Clinical Chemistry, Klinikum Grosshadern, University of Munich, Germany.
Modic
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Hammer
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D000818:Animals; D001646:Bile / Q000187:drug effects / Q000378:metabolism; D015377:Cilastatin / Q000494:pharmacology*; D016572:Cyclosporine / Q000378:metabolism* / Q000493:pharmacokinetics; D003600:Cytosol / Q000378:metabolism; D015378:Imipenem / Q000494:pharmacology*; D007654:Ketoconazole / Q000494:pharmacology; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D010634:Phenobarbital / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D015377:Cilastatin; D015378:Imipenem; D016572:Cyclosporine; D007654:Ketoconazole; D010634:Phenobarbital