[Which factors cause type-1 diabetes?].
Type 1 diabetes is due to selective and irreversible destruction of pancreatic beta-cells via an autoimmune process. The pathogenetic course is dependent both upon genetic predisposition for the disease and upon one or more environmental factors--eg, viral infection, dietary factors, and exposure to toxins or mental stress.
Akerblom
H K
HK
II pediatriska klinken, Helsingfors Universitetscentralsjukhus.
D001327:Autoimmune Diseases / Q000276:immunology*; D003922:Diabetes Mellitus, Type 1 / Q000235:genetics / Q000276:immunology*; D004032:Diet; D004044:Dietary Proteins / Q000009:adverse effects; D004777:Environment; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D007515:Islets of Langerhans / Q000276:immunology*; D008285:Major Histocompatibility Complex / Q000235:genetics; D009602:Nitrosamines / Q000009:adverse effects; D014777:Virus Diseases / Q000150:complications
D004044:Dietary Proteins; D006680:HLA Antigens; D009602:Nitrosamines
Vilka faktorer orsakar typ 1-diabetes?