title: Managing apparent ureteropelvic junction obstruction in the newborn.
abstract: A total of 97 newborns with apparent ureteropelvic junction obstruction was evaluated from mid 1984 to 1989. Evaluation and management are described. Of these patients 39 with an affected kidney showing good initial differential function (greater than 35%) by diethylenetriaminepentaacetic acid scan and 2 showing diminished function (less than 35%) were followed nonoperatively. Six patients (15%) eventually required pyeloplasty for diminishing function (4), urinary tract infections (1) or symptoms of colic (1). The 4 patients with diminishing function improved after pyeloplasty to at least the initial level. A total of 12 patients with good initial function (greater than 35%) of the affected kidney underwent early pyeloplasty (within 6 weeks of diagnosis). They were compared to the similar group of patients managed nonoperatively and followed by sequential renal scans. Eventual changes in percentage differential function in the nonoperative and early surgery groups were +2.8% and +4.1%, respectively. Changes in extraction factor were +0.8% (nonoperative group) and +0.9% (surgery group). No statistically significant difference was found. In the kidney with apparent ureteropelvic junction obstruction and good function, an initial nonoperative approach with sequential renal scan followup and pyeloplasty as needed appears to be reasonable and has resulted in no permanent loss of function.
authors.affiliation: Division of Urology, Children's Hospital of Philadelphia, Pennsylvania 19104.
authors.forename: P C
authors.initials: PC
authors.lastname: Cartwright
authors.forename: J W
authors.initials: JW
authors.lastname: Duckett
authors.forename: M A
authors.initials: MA
authors.lastname: Keating
authors.forename: H M
authors.initials: HM
authors.lastname: Snyder
authors.forename: J
authors.initials: J
authors.lastname: Escala
authors.forename: B
authors.initials: B
authors.lastname: Blyth
authors.forename: S
authors.initials: S
authors.lastname: Heyman
mesh_terms: D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D007682:Kidney Pelvis; D012189:Retrospective Studies; D014517:Ureteral Obstruction / Q000503:physiopathology / Q000601:surgery / Q000628:therapy*