title: Behaviour of mouse macrophage cell line and mouse fibroblast on copolymers containing cellulose triacetate.
abstract: Copolymers containing cellulose triacetate were prepared under various conditions. A bacteriological plastic dish was coated with the copolymer (HCTA-MDI copolymer) composed of hydrolysed cellulose triacetate (HCTA) and diphenylmethane diisocyanate (MDI). The deacetylated copolymer (DA-copolymer) was prepared by the deacetylation of HCTA-MDI copolymer. The behaviour of animal cells such as a mouse macrophage cell line (A640-BB-2 cells) and a mouse fibroblast (3T6 cells) on prepared dishes was investigated morphologically. A640-BB-2 cells showed good adhesion and smooth spreading, and 3T6 cells also showed good adhesion and sufficient cell growth on the dish coated with HCTA-MDI copolymer. These results suggest that these copolymers are useful for biomedical materials.
authors.affiliation: Department of Materials Science, Faculty of Engineering, Tottori University, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Shigemasa
authors.forename: H
authors.initials: H
authors.lastname: Sashiwa
authors.forename: S
authors.initials: S
authors.lastname: Tanioka
authors.forename: H
authors.initials: H
authors.lastname: Saimito
authors.forename: T
authors.initials: T
authors.lastname: Tanigawa
authors.forename: Y
authors.initials: Y
authors.lastname: Tanaka
mesh_terms: D000818:Animals; D002448:Cell Adhesion; D002455:Cell Division; D002460:Cell Line; D002482:Cellulose / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D003485:Cyanates / Q000737:chemistry; D005347:Fibroblasts / Q000166:cytology*; D006868:Hydrolysis; D017953:Isocyanates; D007700:Kinetics; D008264:Macrophages / Q000166:cytology*; D051379:Mice; D008807:Mice, Inbred BALB C; D011108:Polymers; D001559:Benzhydryl Compounds
chemical_list: D002482:Cellulose; D003485:Cyanates; D017953:Isocyanates; D011108:Polymers; C024671:cellulose triacetate; C005969:4,4'-diphenylmethane diisocyanate; D001559:Benzhydryl Compounds