title: [Small intestinal ulceration and stenosis induced by non-steroidal anti-inflammatory agents].
abstract: We report a case who developed a small bowel ulceration in a long segment of distal duodenum and proximal jejunum, a few days after he had taken high doses of diclofenac. After a month, it was complicated by a stenosis of the same segment. Nonsteroidal antiinflammatory drugs have recently been recognised as a possible etiologic factor of small bowel ulcerations. Clinical findings are aspecific. Complications of small bowel ulcerations are: obstruction, perforation or bleeding. Those have to be treated by surgery. We proposed a physiopathologic model and correlated it with histological findings.
  
  
  CONCLUSIONS
  careful prescription of those drugs has to be pursued and one should think about a small bowel ulceration in a patient with an abdominal syndrome, who takes non-steroidal antiinflammatory drugs.
authors.affiliation: Dienst Heelkunde, St. Vincentiusziekenhuis Antwerpen, Universitaire Instelling Antwerpen.
authors.forename: T
authors.initials: T
authors.lastname: Chapelle
authors.forename: S
authors.initials: S
authors.lastname: Reher
authors.forename: P
authors.initials: P
authors.lastname: Devriendt
authors.forename: L
authors.initials: L
authors.lastname: Colemont
authors.forename: E
authors.initials: E
authors.lastname: Van Moer
authors.forename: Y
authors.initials: Y
authors.lastname: Van der Stighelen
authors.forename: E
authors.initials: E
authors.lastname: Eyskens
mesh_terms: D000368:Aged; D004008:Diclofenac / Q000009:adverse effects* / Q000494:pharmacology; D004381:Duodenal Ulcer / Q000139:chemically induced*; D006801:Humans; D007413:Intestinal Mucosa / Q000187:drug effects; D007415:Intestinal Obstruction / Q000139:chemically induced* / Q000601:surgery; D007579:Jejunal Diseases / Q000139:chemically induced*; D008297:Male; D014456:Ulcer / Q000139:chemically induced
chemical_list: D004008:Diclofenac
vernacular_title: Dundarmulceratie en -stenose geïnduceerd door niet-steroïdale anti-inflammatoire farmaca.