Progress in the treatment of childhood leukaemias.
The Nordic Society for Pediatric Hematology and Oncology (NOPHO) has run a population-based registry on all cases of acute leukaemias in the Nordic countries since 1981. Data on close to 2000 children with these diagnoses are presented and used as a background for a general discussion of progress in the therapy of these challenging conditions. Our material is unique in that it is population based. The results obtained are comparable to those obtained by all other major cooperative groups. Since January 1992, the treatment protocols for all types of acute leukaemias in childhood have been harmonized in the Nordic countries.
Lie
S O
SO
Department of Pediatrics, University Hospital, Oslo, Norway.
Gustafsson
G
G
D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001921:Brain / Q000528:radiation effects; D002648:Child; D002675:Child, Preschool; D003718:Denmark / Q000453:epidemiology; D005260:Female; D005387:Finland / Q000453:epidemiology; D006801:Humans; D007055:Iceland / Q000453:epidemiology; D007223:Infant; D015470:Leukemia, Myeloid, Acute / Q000453:epidemiology / Q000401:mortality / Q000628:therapy*; D008297:Male; D015999:Multivariate Analysis; D009664:Norway / Q000453:epidemiology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000453:epidemiology / Q000401:mortality / Q000628:therapy*; D011336:Probability; D011379:Prognosis; D012008:Recurrence; D012042:Registries; D012307:Risk Factors; D013548:Sweden / Q000453:epidemiology