title: [Stability and chemosensitivity of Plasmodium falciparum to chloroquine in 1990 and 1991 in Ankazobe, a village in high plateau Madagascar].
abstract: The in vivo and in vitro response of Plasmodium falciparum to chloroquine was conducted in Ankazobe, a village located in the high plateau area. These studies confirmed the low level of chloroquine-resistance. The in vivo data indicate the absence of increase resistance during the 2 years study. Chloroquine is still the drug of choice for the treatment of malaria attack in this area.
authors.affiliation: Unité de Recherche sur le Paludisme, Institut Pasteur de Madagascar, Antananarivo.
authors.forename: P
authors.initials: P
authors.lastname: Ringwald
authors.forename: P
authors.initials: P
authors.lastname: Rabarison
authors.forename: L
authors.initials: L
authors.lastname: Raharimalala
authors.forename: M D
authors.initials: MD
authors.lastname: Rason
authors.forename: J P
authors.initials: JP
authors.lastname: Lepers
authors.forename: J
authors.initials: J
authors.lastname: Le Bras
authors.forename: J
authors.initials: J
authors.lastname: Roux
mesh_terms: D000818:Animals; D002738:Chloroquine / Q000494:pharmacology* / Q000627:therapeutic use; D004351:Drug Resistance; D006801:Humans; D008270:Madagascar; D016778:Malaria, Falciparum / Q000188:drug therapy / Q000469:parasitology; D010963:Plasmodium falciparum / Q000187:drug effects*
chemical_list: D002738:Chloroquine
vernacular_title: Stabilité de la chimiosensibilité de Plasmodium falciparum a la chloroquine en 1990 et 1991 a Ankazobe, village des hauts plateaux malgaches.