title: Acquisition of coccidioidomycosis at necropsy by inhalation of coccidioidal endospores.
abstract: Coccidioidomycosis is accepted as being noncontagious because the infectious arthroconidial form of Coccidioides immitis is not produced in humans and other mammalian hosts. However, disseminated coccidioidomycosis developed in a veterinarian who autopsied a horse with disseminated disease but without draining lesions or productive cough. We postulate transmission occurred by inhalation of tissue-phase endospores aerosolized in the course of dissection.
authors.affiliation: Department of Internal Medicine, University of California, Davis Medical Center, Sacramento 95817.
authors.forename: G J
authors.initials: GJ
authors.lastname: Kohn
authors.forename: S R
authors.initials: SR
authors.lastname: Linné
authors.forename: C M
authors.initials: CM
authors.lastname: Smith
authors.forename: P D
authors.initials: PD
authors.lastname: Hoeprich
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000818:Animals; D001344:Autopsy / Q000662:veterinary*; D003045:Coccidioides / Q000302:isolation & purification; D003047:Coccidioidomycosis / Q000188:drug therapy / Q000635:transmission* / Q000662:veterinary; D006734:Horse Diseases / Q000635:transmission; D006736:Horses; D006801:Humans; D008172:Lung Diseases, Fungal / Q000188:drug therapy / Q000209:etiology; D008297:Male; D016921:Meningitis, Fungal / Q000188:drug therapy; D009784:Occupational Diseases / Q000188:drug therapy / Q000209:etiology*; D013172:Spores, Fungal; D014730:Veterinary Medicine
chemical_list: D000666:Amphotericin B