title: Inhibitory effects of AcSDKP on the mixed lymphocyte reaction (MLR). Part I. MLR with mouse spleen cells.
abstract: AcSDKP (inhibitor of entry into cycle of pluripotent hemopoietic stem cells) is able to decrease mixed lymphocyte reaction intensity when H-2 incompatible allogeneic spleen cells are used as stimulators. This is a first approach to determining whether AcSDKP has potential therapeutic value for clinical bone marrow transplantation.
authors.affiliation: Faculté de Médecine de Limoges, Laboratoire de Biochimie Médicale, Limoges, France.
authors.forename: E
authors.initials: E
authors.lastname: Frindel
authors.forename: A
authors.initials: A
authors.lastname: Massé
authors.forename: L
authors.initials: L
authors.lastname: Volkov
authors.forename: C
authors.initials: C
authors.lastname: Lavignac
authors.forename: M
authors.initials: M
authors.lastname: Rigaud
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D066298:In Vitro Techniques; D008213:Lymphocyte Activation / Q000187:drug effects*; D007959:Lymphocyte Culture Test, Mixed; D008214:Lymphocytes / Q000187:drug effects*; D051379:Mice; D008815:Mice, Inbred Strains; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000494:pharmacology*; D013154:Spleen / Q000166:cytology
chemical_list: D009842:Oligopeptides; C058504:goralatide