[The effect of ionizing radiation on the vascular bed of the skin in ontogeny. The function of the microcirculatory bed of the skin in the fetuses of white rats sublethally irradiated].
Albino female rats were exposed to X radiation (5 Gy, 180 kV, 10 mA, filter 0.5 mm Cu) on days 10-15 of pregnancy. After 3 and 7 days they were sacrificed (under ether anesthesia) and fetuses were extracted. The status of the lympho- and hemomicrocirculatory beds (LMCB and HMCB) of the fetus back skin was studied by the macro- and microscopic methods. As early as day 3 of radiation sickness the diameter of LMCB vessels increased by 1.4-1.9 times, whereas changes in GMCB were less pronounced. On day 7, there was a progressive increase in dilatation of LMCB vessels, alongside with the narrowing of large units (arteries and veins). The development of the connective framework of the fetus skin was retarded.
Malinovskiĭ
S V
SV
Kostesha
N Ia
NIa
D000818:Animals; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006652:Histological Techniques; D008208:Lymphatic System / Q000196:embryology / Q000528:radiation effects; D008833:Microcirculation / Q000196:embryology / Q000528:radiation effects; D011247:Pregnancy; D051381:Rats; D012867:Skin / Q000098:blood supply / Q000196:embryology / Q000528:radiation effects*; D013997:Time Factors
Vliianie ioniziruiushchego izlucheniia na sosudistoe ruslo kozhi v ontogeneze. Sostoianie mikrotsirkuliatornogo rusla kozhi plodov belykh krys pri subletal'nom obluchenii.