title: The natural history of acute disseminated leukoencephalitis. A serial magnetic resonance imaging study.
abstract: The natural history of acute disseminated (leuko)encephalitis (ADE) in a 3-year-old girl who did not receive steroid therapy is reported. Serial MR studies disclosed: 1) white matter lesions resolved spontaneously, though very slowly, 2) active disease persisted for around three months and coincided with the onset of new subcortical lesions. These subcortical lesions were associated with hyperactivity, suggesting a possible etiologic correlation.
authors.affiliation: Department of Pediatrics, Yokohama City University School of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Kimura
authors.forename: T
authors.initials: T
authors.lastname: Unayama
authors.forename: T
authors.initials: T
authors.lastname: Mori
mesh_terms: D000208:Acute Disease; D001921:Brain / Q000473:pathology; D001925:Brain Damage, Chronic / Q000175:diagnosis; D002648:Child; D004660:Encephalitis / Q000175:diagnosis*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D009460:Neurologic Examination; D011595:Psychomotor Agitation / Q000175:diagnosis*