title: Screening for early ovarian cancer.
abstract: Transvaginal ultrasound scanning with colour Doppler imaging can be used to detect early ovarian cancer. About one in three women with a family history of the disease and a positive screening result (i.e. a persistent intraovarian mass with a characteristic blood supply) will have histological signs of primary cancer. A randomized controlled clinical trial should be undertaken to assess whether screening and immediate treatment of women from the general population will improve survival rates from the disease.
authors.affiliation: King's College School of Medicine and Dentistry, London.
authors.forename: T H
authors.initials: TH
authors.lastname: Bourne
authors.forename: J
authors.initials: J
authors.lastname: Hampson
authors.forename: K
authors.initials: K
authors.lastname: Reynolds
authors.forename: W P
authors.initials: WP
authors.lastname: Collins
authors.forename: S
authors.initials: S
authors.lastname: Campbell
mesh_terms: D015295:Antigens, Tumor-Associated, Carbohydrate / Q000097:blood; D014408:Biomarkers, Tumor / Q000097:blood; D002985:Clinical Protocols / Q000592:standards; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000379:methods / Q000592:standards*; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control*; D012307:Risk Factors; D012680:Sensitivity and Specificity; D014463:Ultrasonography; D014621:Vagina / Q000000981:diagnostic imaging
chemical_list: D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor