The spectrum of concentric macro EMG correlations. Part II. Patients with diseases of muscle and nerve.
In the second part of this study we investigate the correlations between the concentric and conmac action potentials in motor units of individuals with diseases of muscle and nerve. We studied 86 myopathic and 86 neurogenic motor units and compared their concentric and conmac action potentials. In the patients with myopathy, we found that the concentric motor unit action potential's (MUAP) area correlates strongly with the conmac potential, even better than in normals, while its amplitude correlates less. In the neurogenic group, we found that both the concentric MUAP's area and amplitude correlated very well with their conmac counterpart, more so than in normals. Thus, in pathology, as in normals, measuring the concentric MUAP's area in addition to its amplitude adds to the diagnostic sensitivity of motor unit potential measurements. These findings are discussed in light of the known dynamic and architectural motor unit changes which take place in the myopathic and neurogenic motor unit.
Gan
R
R
Department of Neurology, Boston University School of Medicine, Boston VA Outpatient Clinic, Massachusetts.
Jabre
J F
JF
D000200:Action Potentials / Q000502:physiology; D004566:Electrodes; D004576:Electromyography / Q000295:instrumentation / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology*; D009119:Muscle Contraction / Q000502:physiology; D009132:Muscles / Q000294:innervation; D009135:Muscular Diseases / Q000175:diagnosis* / Q000503:physiopathology; D009468:Neuromuscular Diseases / Q000175:diagnosis* / Q000503:physiopathology; D012680:Sensitivity and Specificity