[Three cases of acute methamphetamine intoxication--analysis of optically active methamphetamine].
Three typical cases of acute methamphetamine intoxication are reported. The concentrations of methamphetamine in the blood were 27.2, 6.43 and 0.60 micrograms/ml, respectively. All three victims had been exposed to high temperature in a bathroom or a closed room in summer at the time of death. Macroscopic autopsy revealed hemorrhagic pulmonary edema, and histologically, diffuse contraction-band necrosis was evident in the myocardium in all cases. The absolute structures of six illegally available methamphetamine showed an (S)-configuration with an optical purity of > 99% in enantiomeric excess and four were racemic form.
Mori
A
A
Department of Legal Medicine School of Medicine, Teikyo University.
Suzuki
H
H
Ishiyama
I
I
D000328:Adult; D005260:Female; D005334:Fever / Q000473:pathology; D006801:Humans; D008297:Male; D008694:Methamphetamine / Q000032:analysis* / Q000506:poisoning*; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology; D009336:Necrosis; D011654:Pulmonary Edema / Q000473:pathology; D013237:Stereoisomerism
D008694:Methamphetamine