title: Trisomy 7 in nonneoplastic focal steatosis of the liver.
abstract: Cytogenetic analysis of short-term cultures of a nonneoplastic focal steatosis of the liver showed trisomy 7 as the sole chromosomal change. This finding, especially when viewed in light of previous reports describing +7 in nonneoplastic tissues, strongly suggests that trisomy 7 cannot be considered a tumor-specific abnormality when it occurs as the only change. The cell type in which +7 is present is not yet known.
authors.affiliation: Department of Clinical Genetics, Lund University Hospital, Sweden.
authors.forename: G
authors.initials: G
authors.lastname: Bardi
authors.forename: B
authors.initials: B
authors.lastname: Johansson
authors.forename: N
authors.initials: N
authors.lastname: Pandis
authors.forename: S
authors.initials: S
authors.lastname: Heim
authors.forename: N
authors.initials: N
authors.lastname: Mandahl
authors.forename: I
authors.initials: I
authors.lastname: Hägerstrand
authors.forename: T
authors.initials: T
authors.lastname: Holmin
authors.forename: A
authors.initials: A
authors.lastname: Andrén-Sandberg
authors.forename: F
authors.initials: F
authors.lastname: Mitelman
mesh_terms: D000328:Adult; D002897:Chromosomes, Human, Pair 7; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology / Q000648:ultrastructure; D008107:Liver Diseases / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014314:Trisomy