Foveal hypoplasia in complete oculocutaneous albinism. A histopathologic study.
Histopathologic and ultrastructural findings in an eye from a patient with complete oculocutaneous albinism are reported. Examination revealed posterior embryotoxon, high myopia, no foveal differentiation, and absence of melanin pigment in all ocular structures. A few nonmembrane-bound electron-dense granules of lipofuscin were present in the iris and retinal pigment epithelial cells.
Mietz
H
H
Wilmer Ophthalmological Institute, Johns Hopkins Medical Institutions, Baltimore, MD.
Green
W R
WR
Wolff
S M
SM
Abundo
G P
GP
D000368:Aged; D000369:Aged, 80 and over; D016115:Albinism, Oculocutaneous / Q000473:pathology*; D005260:Female; D005584:Fovea Centralis / Q000002:abnormalities* / Q000648:ultrastructure; D006801:Humans; D010857:Pigment Epithelium of Eye / Q000648:ultrastructure; D012160:Retina / Q000648:ultrastructure; D014602:Uvea / Q000648:ultrastructure