title: Glutamate receptor expression in the rat retina.
abstract: The expression of five genes (GluR A; B; C; D; GluR 5) encoding functional subunits of glutamate receptors was investigated in the rat retina using in situ hybridization with oligonucleotide probes. All five genes are expressed in the retina. All probes label cell bodies in the ganglion cell layer as well as somata in the inner third of the inner nuclear layer (INL), where the amacrine cells are located. In addition GluR 5, B and D, and to a lesser extent also GluR A are found in the middle and outer part of the INL, where bipolar and horizontal cells reside. Different subsets of retinal neurons may thus use glutamate receptors of different subunit composition.
authors.affiliation: Max-Planck-Institut für Hirnforschung, Neuroanatomische Abteilung, Frankfurt, FRG.
authors.forename: F
authors.initials: F
authors.lastname: Müller
authors.forename: U
authors.initials: U
authors.lastname: Greferath
authors.forename: H
authors.initials: H
authors.lastname: Wässle
authors.forename: W
authors.initials: W
authors.lastname: Wisden
authors.forename: P
authors.initials: P
authors.lastname: Seeburg
mesh_terms: D000818:Animals; D001345:Autoradiography; D002531:Cerebellum / Q000502:physiology*; D015870:Gene Expression; D005971:Glutamates / Q000378:metabolism; D046911:Macromolecular Substances; D009693:Nucleic Acid Hybridization; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D017470:Receptors, Glutamate / Q000235:genetics*; D012160:Retina / Q000502:physiology*; D012165:Retinal Ganglion Cells / Q000502:physiology; D013462:Sulfur Radioisotopes
chemical_list: D005971:Glutamates; D046911:Macromolecular Substances; D012333:RNA, Messenger; D017470:Receptors, Glutamate; D013462:Sulfur Radioisotopes