Occurrence of an actin-inserting domain in tensin.
We have previously described a protein called "insertin" that binds strongly to barbed ends of actin filaments and permits polymerization of actin filaments by insertion of actin monomers between the barbed ends and barbed end-bound insertin. We determined the amino acid sequence of insertin and found that the primary structure of insertin is almost identical to amino acid residues 862 to 1212 of the actin-binding protein tensin.
Weigt
C
C
Institute of Physiological Chemistry, Ruhr-University Bochum, Germany.
Gaertner
A
A
Wegner
A
A
Korte
H
H
Meyer
H E
HE
D000199:Actins / Q000378:metabolism*; D000595:Amino Acid Sequence; D030161:Avian Proteins; D008840:Microfilament Proteins / Q000737:chemistry* / Q000378:metabolism; D008969:Molecular Sequence Data; D017386:Sequence Homology, Amino Acid; D000070876:Tensins
D000199:Actins; D030161:Avian Proteins; D008840:Microfilament Proteins; D000070876:Tensins; C077008:insertin protein, chicken