title: Long term results of percutaneous transluminal valvuloplasty in patients with valvular aortic stenosis.
abstract: The results of percutaneous balloon aortic valvuloplasty (PBAV) in 62 consecutive patients with valvular aortic stenosis are reported. The age of the patients ranged from 11 months to 72 years (mean 28 +/- 12 years). Hemodynamically successful dilatation was achieved in 58 out of 62 patients. This was associated with marked clinical improvement in these patients. The left ventricular aortic peak to peak gradient decreased from 96.67 +/- 38.4 to 28.14 +/- 26.5mmHg (p < 0.01). There were no deaths during the procedure. Only one patient died in the hospital during the same admission. There was an increase in aortic regurgitation (AR) by at least one grade in 25 (40.3%) patients. Femoral arterial thrombosis was seen in 9/62 patients, 5 of them requiring surgical intervention. Follow up was available in 28 (45.1%) patients over a period of 2-15 months (mean 9 +/- 3 months). Two patients died during the follow up period. Doppler evaluation of gradients was done in all 28 patients with 15 consenting to undergo repeat cardiac catheterisation. Although hemodynamically the restenosis rate was 35.7% (10/28), only 2 of these patients showed symptomatic deterioration. The success of dilatation and restenosis rate were independent of the etiology of aortic stenosis, presence of calcification and the number of balloons used. This study demonstrates that PBAV is feasible in valvular aortic stenosis at low risk and is able to produce significant clinical and hemodynamic improvement in most cases with a restenosis rate of 35.7% at a follow up period of 9 +/- 3 months.
authors.affiliation: Department of Cardiology, King Edward VII Memorial Hospital, Bombay.
authors.forename: P A
authors.initials: PA
authors.lastname: Kale
authors.forename: S V
authors.initials: SV
authors.lastname: Sathe
authors.forename: R M
authors.initials: RM
authors.lastname: Rajani
authors.forename: Y Y
authors.initials: YY
authors.lastname: Lokhandwala
authors.forename: S D
authors.initials: SD
authors.lastname: Silva
authors.forename: V K
authors.initials: VK
authors.lastname: Mehan
authors.forename: V K
authors.initials: VK
authors.lastname: Kaneria
authors.forename: H L
authors.initials: HL
authors.lastname: Kulkarni
authors.forename: B V
authors.initials: BV
authors.lastname: Dalvi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001024:Aortic Valve Stenosis / Q000503:physiopathology / Q000628:therapy*; D002404:Catheterization; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006439:Hemodynamics; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D016896:Treatment Outcome