Subchondral vascularisation and osteoarthritis.
A prospective experiment was carried out in 40 rabbits in which the blood supply to the patella was interrupted for defined periods from 2 weeks to 6 months. With prolonged ischaemia, there were clear changes in the articular cartilage which were comparable with those seen in human osteoarthritis.
Graf
J
J
Department of Orthopaedic Surgery, University of Heidelberg, Federal Republic of Germany.
Neusel
E
E
Freese
U
U
Simank
H G
HG
Niethard
F U
FU
D000818:Animals; D002358:Cartilage, Articular / Q000098:blood supply* / Q000648:ultrastructure; D010003:Osteoarthritis / Q000473:pathology / Q000503:physiopathology*; D010329:Patella / Q000098:blood supply*; D011817:Rabbits; D013997:Time Factors