title: Cerebrospinal fluid T cell receptor gamma/delta+ lymphocyte subsets in patient with AIDS-dementia complex.
abstract: A subset of peripheral T cells, whose physiological function is little known, expresses a distinct CD3-associated receptor composed of gamma and delta chains. We used two monoclonal antibodies to characterize the TcR gamma/delta lymphocytes (TcR delta 1+) and their fraction (TcS delta 1+) in peripheral blood and cerebrospinal fluid of patients affected by AIDS dementia complex (ADC). Thirty patients with ADC and a control group of twenty individuals with other non-inflammatory neurological diseases (OND) were recruited. Our results demonstrate that the TcR gamma/delta cells were also present in cerebrospinal fluid of ADC patients, but we did not find any statistical difference between the two groups.
authors.affiliation: III Department D, Cotugno Hospital for Infectious Diseases, Napoli, Italy.
authors.forename: O
authors.initials: O
authors.lastname: Perrella
authors.forename: M
authors.initials: M
authors.lastname: Soscia
authors.forename: C
authors.initials: C
authors.lastname: Iaccarino
authors.forename: P B
authors.initials: PB
authors.lastname: Carrieri
mesh_terms: D015526:AIDS Dementia Complex / Q000134:cerebrospinal fluid / Q000276:immunology*; D000293:Adolescent; D000328:Adult; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D008297:Male; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000378:metabolism*; D016176:T-Lymphocyte Subsets / Q000276:immunology*
chemical_list: D016692:Receptors, Antigen, T-Cell, gamma-delta