title: [Determination of the cerebrovascular reserve capacity by using acetazolamide as well as transcranial Doppler and SPECT tests].
abstract: The aim of this study was the development of a simple bedside test to assess cerebrovascular reserve capacity using transcranial Doppler sonography. We tried to validate the increase in blood flow velocity as cerebrovascular reserve capacity in 20 (3 normal, 7 TIA, 10 completed stroke) patients. They were studied using transcranial Doppler sonography and rCBF SPECT before and after injection of 1 g acetazolamide. Their increases in blood flow velocity and changes in cerebral blood flow correlated significantly in the symptomatic hemispheres (p less than 0.001). Blood flow velocity between the two hemispheres (symptomatic and asymptomatic) was not significantly different at rest. We offer these simple and reliable methods in clinical studies to clarify the frequency of ischemic stroke of hemodynamic origin.
authors.affiliation: Szent-Györgyi Albert Orvostudományi Egyetem, Szeged.
authors.forename: P
authors.initials: P
authors.lastname: Barzó
authors.forename: L
authors.initials: L
authors.lastname: Pávics
authors.forename: L
authors.initials: L
authors.lastname: Borda
authors.forename: M
authors.initials: M
authors.lastname: Bodosi
authors.forename: T
authors.initials: T
authors.lastname: Dóczi
authors.forename: E
authors.initials: E
authors.lastname: Katona
mesh_terms: D000086:Acetazolamide / Q000008:administration & dosage; D001783:Blood Flow Velocity; D002560:Cerebrovascular Circulation / Q000502:physiology*; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000517:prevention & control; D004453:Echoencephalography; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000175:diagnosis; D015899:Tomography, Emission-Computed, Single-Photon; D014655:Vascular Resistance / Q000502:physiology
chemical_list: D000086:Acetazolamide
vernacular_title: Az agyi rezisztenciaerek rezervkapacitásának meghatározása acetazolamid teszt során végzett transcranialis Doppler és SPECT vizsgálattal.