title: Biometry and auto-fluorescence of the anterior ocular segment in diabetics with and without autonomic neuropathy: a case control study.
abstract: The biometry and auto-fluorescence of the anterior ocular segment were examined in a case control study of two populations of diabetics. Cases, with diabetic autonomic neuropathy, and controls without neuropathy (forty in each group) were selected from a community based diabetic population and matched individually for age, sex, and type of diabetes. Scheimpflug and auto-fluorescence anterior segment photography were performed and analysed by digital image analysis in a masked fashion. There were differences between the groups in axial lens thickness, front radius of curvature of the lens, anterior chamber depth and lenticular auto-fluorescence. These findings are discussed in the context of the known association between autonomic neuropathy and narrow angle glaucoma, and possible common mechanisms of tissue damage in diabetes.
authors.affiliation: Nuffield Laboratory of Ophthalmology, University of Oxford.
authors.forename: J M
authors.initials: JM
authors.lastname: Sparrow
authors.forename: H A
authors.initials: HA
authors.lastname: Neil
authors.forename: A J
authors.initials: AJ
authors.lastname: Bron
mesh_terms: D000368:Aged; D000375:Aging / Q000473:pathology; D000869:Anterior Eye Segment / Q000473:pathology*; D001342:Autonomic Nervous System Diseases / Q000473:pathology*; D001699:Biometry; D016022:Case-Control Studies; D003920:Diabetes Mellitus / Q000473:pathology; D003929:Diabetic Neuropathies / Q000473:pathology*; D005260:Female; D005453:Fluorescence; D006801:Humans; D008297:Male; D008875:Middle Aged