[The application of circular dichroism on the structure analysis of natural products--diterpenoid dilactones and tylophorines].
In this paper, circular dichroism (CD), sector projection and reverse octant rule projection of four diterpenoid dilactones and five tylophorines (two of them, 6, 8, are new compounds) are reported in which reverse octant rule projection is the first application to the configuration determination of diterpenoid dilactone. By using these rules, the predicted Cotton effects of these compounds coincided with the result of previous determinations, so, their absolute configurations are assigned.
Mi
J F
JF
Shanghai Institute of Materia Medica, Academia Sinica.
Fang
S D
SD
Chen
Y
Y
Xu
Y M
YM
Zhang
R
R
D000470:Alkaloids; D002942:Circular Dichroism; D004224:Diterpenes / Q000737:chemistry* / Q000302:isolation & purification; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D007212:Indolizines / Q000737:chemistry* / Q000302:isolation & purification; D007783:Lactones / Q000737:chemistry* / Q000302:isolation & purification; D008968:Molecular Conformation; D010616:Phenanthrenes
D000470:Alkaloids; D004224:Diterpenes; D004365:Drugs, Chinese Herbal; D007212:Indolizines; D007783:Lactones; D010616:Phenanthrenes; C004218:tylophorine