title: Cytogenetic evidence of intratumoral focal heterogeneity in prostatic carcinomas.
abstract: Although prostatic cancer is the most common malignant disease in men in western countries, only limited data on chromosomal changes are available. We report on our cytogenetic findings in cell cultures from four primary prostatic carcinomas indicating the existence of intratumoral focal heterogeneity concerning chromosomal anomalies in prostatic cancer.
authors.affiliation: Institut für Humangenetik, Universität des Saarlandes, Homburg/Saar, Deutschland.
authors.forename: B
authors.initials: B
authors.lastname: Wullich
authors.forename: T
authors.initials: T
authors.lastname: Breitkreuz
authors.forename: T
authors.initials: T
authors.lastname: Zwergel
authors.forename: G
authors.initials: G
authors.lastname: Unteregger
authors.forename: G
authors.initials: G
authors.lastname: Seitz
authors.forename: K D
authors.initials: KD
authors.lastname: Zang
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics* / Q000473:pathology; D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D006801:Humans; D007621:Karyotyping; D008297:Male; D011471:Prostatic Neoplasms / Q000235:genetics* / Q000473:pathology; D014407:Tumor Cells, Cultured