Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells.
Hartwell
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Department of Genetics, University of Washington, Seattle 98195.
D002453:Cell Cycle / Q000235:genetics*; D002471:Cell Transformation, Neoplastic / Q000235:genetics*; D005784:Gene Amplification / Q000235:genetics; D016158:Genes, p53 / Q000235:genetics*; D006801:Humans; D009154:Mutation / Q000235:genetics; D009369:Neoplasms / Q000235:genetics*