title: Hairy cell leukemia and factor VIII inhibitor: a case report.
abstract: Acquired factor VIII inhibitors are usually described in hemophilia A, although some cases have been documented in chronic inflammatory diseases and malignant tumors. We report here the first case of a factor VIII inhibitor appearing in the course of hairy cell leukemia. Interferon therapy over a 5 month period led to complete remission of leukemia with parallel disappearance of the acquired factor VIII inhibitor.
authors.affiliation: Service d'Onco-Hématologie, CHU Hautepierre, Strasbourg, France.
authors.forename: A
authors.initials: A
authors.lastname: Komminoth
authors.forename: P
authors.initials: P
authors.lastname: Dufour
authors.forename: J P
authors.initials: JP
authors.lastname: Bergerat
authors.forename: M L
authors.initials: ML
authors.lastname: Wiesel
authors.forename: A
authors.initials: A
authors.lastname: Falkenrodt
authors.forename: F
authors.initials: F
authors.lastname: Oberling
mesh_terms: D005169:Factor VIII / Q000037:antagonists & inhibitors*; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use; D007943:Leukemia, Hairy Cell / Q000097:blood* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012074:Remission Induction / Q000379:methods
chemical_list: D016898:Interferon-alpha; D005169:Factor VIII