Endothelial decompensation in a schizophrenic patient receiving long-term treatment with tranquilizers.
Bilateral corneal edema occurred in a schizophrenic patient receiving tranquilizers. This particular corneal edema was rapidly resolved after tranquilizer discontinuation. Specular microscopic examination disclosed marked enlargement of the corneal endothelium. This endothelial impairment may have been due to long-term administration of tranquilizers.
Nishida
K
K
Department of Ophthalmology, Osaka University Medical School, Japan.
Ohashi
Y
Y
Kinoshita
S
S
Kiritoshi
A
A
Manabe
R
R
D000328:Adult; D002452:Cell Count; D015715:Corneal Edema / Q000139:chemically induced* / Q000473:pathology; D004334:Drug Administration Schedule; D004728:Endothelium, Corneal / Q000187:drug effects* / Q000473:pathology; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D012559:Schizophrenia / Q000188:drug therapy*; D014149:Tranquilizing Agents / Q000009:adverse effects* / Q000627:therapeutic use
D014149:Tranquilizing Agents