title: Porokeratosis in immunosuppressed and nonimmunosuppressed patients.
abstract: Porokeratosis is an uncommon, inherited, autosomally dominant disorder. In the last decade association of porokeratosis and immunosuppression has been observed. In this study we carried out a comparative study between immunosuppressed and nonimmunosuppressed porokeratosis cases. We found that 9 out of 20 cases of porokeratosis were associated with organ transplantation/immunosuppression. Clinicopathologic study revealed that the pattern of disease is alike both in immunosuppressed and nonimmunosuppressed patients. Our observations indicate that immune modulation could be a factor in the genesis of porokeratosis.
authors.affiliation: Department of Dermatology and Pathology, Stanford University School of Medicine, California.
authors.forename: S P
authors.initials: SP
authors.lastname: Raychaudhuri
authors.forename: B R
authors.initials: BR
authors.lastname: Smoller
mesh_terms: D000328:Adult; D016026:Bone Marrow Transplantation / Q000276:immunology; D016027:Heart Transplantation / Q000276:immunology; D006801:Humans; D016867:Immunocompromised Host; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D016030:Kidney Transplantation / Q000276:immunology; D008297:Male; D017499:Porokeratosis / Q000276:immunology*; D013997:Time Factors