Long tail kinetics in biophysics?
Long tail kinetics describe a variety of data from complex, disordered materials that cannot be described by conventional kinetics. It is suggested that the kinetics of diffusive motion in complex biological media, such as cytoplasm or biomembranes, might also have long tails. The effects of long tail kinetics are investigated for two standard biophysical measurements, fluorescence recovery after photobleaching (FRAP), and dynamic light scattering (DLS). It is shown that long tail kinetic data would yield significantly distorted and misleading results when analyzed assuming conventional kinetics.
Nagle
J F
JF
Department of Biological Science, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213.
D007700:Kinetics; D008433:Mathematics; D008954:Models, Biological