Trisomy 15 mosaicism in an IVF fetus.
Prenatal diagnosis of an IVF pregnancy in a woman aged 41 years showed a fetus mosaic for trisomy 15. The fetus had dysmorphic features, hypoplastic adrenal glands, and an accessory spleen. Both IVF and advanced maternal age would seem to increase the risk of trisomy 15.
Bennett
C P
CP
Division of Medical and Molecular Genetics, Guy's Hospital, London.
Davis
T
T
Seller
M J
MJ
D000025:Abortion, Eugenic; D002884:Chromosomes, Human, Pair 15; D005307:Fertilization in Vitro; D005333:Fetus / Q000002:abnormalities*; D006801:Humans; D008297:Male; D009030:Mosaicism / Q000235:genetics*; D011296:Prenatal Diagnosis; D014314:Trisomy