title: Prognostic role of flow cytometry in superficial bladder cancer.
abstract: Prognostic factors in superficial transitional cell carcinoma of the bladder were assessed with histopathological and flow cytometry analysis in a series of 61 patients operated transurethrally between 1988 and 1990. In particular, we evaluated the usefulness of flow cytometry in order to identify patients who require a more accurate clinical follow-up or a more aggressive therapy. A multivariate analysis was done in 61 cases, considering patient age and sex, stage, grade and number of lesions (unifocal or multifocal), post-TUR therapy (therapy or not), and DNA ploidy (diploid/aneuploid). DNA pattern and number of recurrences were determinant for selecting risk cases for progression.
authors.affiliation: Department of Urology, University La Sapienza, Rome, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Di Silverio
authors.forename: M
authors.initials: M
authors.lastname: von Heland
authors.forename: E
authors.initials: E
authors.lastname: De Berardinis
authors.forename: R
authors.initials: R
authors.lastname: Izzi
authors.forename: M
authors.initials: M
authors.lastname: Buscarini
authors.forename: R
authors.initials: R
authors.lastname: De Vita
authors.forename: R
authors.initials: R
authors.lastname: Forte
authors.forename: F
authors.initials: F
authors.lastname: Seccareccia
authors.forename: A
authors.initials: A
authors.lastname: Menotti
mesh_terms: D002295:Carcinoma, Transitional Cell / Q000235:genetics / Q000473:pathology*; D004273:DNA, Neoplasm / Q000032:analysis; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D011003:Ploidies; D011379:Prognosis; D016016:Proportional Hazards Models; D012307:Risk Factors; D001749:Urinary Bladder Neoplasms / Q000235:genetics / Q000473:pathology*
chemical_list: D004273:DNA, Neoplasm