title: [The value of adjuvant irradiation in lymphatic vessel invasion in patients with a cervical carcinoma in histopathological stage Ib and with negative lymph nodes].
abstract: The present retrospective study attempts to evaluate the significance of adjuvant radiotherapy as a prognostic factor for stage Ib cervical carcinoma without lymph node metastases but with lymph-vascular space invasion. 54 patients fulfilled the inclusion criteria: histopathological stage Ib, radical hysterectomy with pelvic lymphadenectomy, negative pelvic lymph nodes and lymph-vascular space involvement. Though larger tumors were found (tumor infiltration of the cervix greater than 2/3) in the irradiated group (chi 2-test p = 0.003), there was no significant difference in the five-year overall survival (92% five-year survival without vs. 90% with adjuvant irradiation). In contrast statistical significant difference was found in recurrence-free interval between these groups (Wilcoxon test p = 0.02).
authors.affiliation: Strahlenabteilung der I. und II. Universitäts-Frauenklinik, Wien.
authors.forename: N
authors.initials: N
authors.lastname: Vavra
authors.forename: P
authors.initials: P
authors.lastname: Sevelda
authors.forename: M
authors.initials: M
authors.lastname: Seifert
authors.forename: J
authors.initials: J
authors.lastname: Timar
authors.forename: I
authors.initials: I
authors.lastname: Kudielka
authors.forename: H
authors.initials: H
authors.lastname: Kucera
mesh_terms: D002277:Carcinoma / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D016009:Chi-Square Distribution; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D009367:Neoplasm Staging; D011182:Postoperative Care; D011879:Radiotherapy Dosage; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery
vernacular_title: Zum Wert der adjuvanten Bestrahlung bei Lymphgefässeinbrüchen bei Patientinnen mit einem Zervixkarzinom im histopathologischen Stadium Ib und negativen Lymphknoten.