In vivo evidence for the Th1/Th2 paradigm: oral alloantigen-induced modulation of accelerated allograft rejection is associated with dense intragraft IL-4.
Hancock
W W
WW
Department of Pathology and Immunology, Monash Medical School, Melbourne, Victoria, Australia.
Sayegh
M H
MH
Carpenter
C B
CB
D000284:Administration, Oral; D000818:Animals; D000917:Antibody Formation; D003176:Complement C3 / Q000032:analysis; D016207:Cytokines / Q000032:analysis / Q000096:biosynthesis*; D006084:Graft Rejection / Q000276:immunology*; D006085:Graft Survival / Q000276:immunology*; D016027:Heart Transplantation / Q000276:immunology* / Q000502:physiology; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007165:Immunosuppression Therapy / Q000379:methods; D015847:Interleukin-4 / Q000032:analysis / Q000096:biosynthesis*; D007519:Isoantigens / Q000008:administration & dosage* / Q000276:immunology; D051381:Rats; D011914:Rats, Inbred BN; D011917:Rats, Inbred Lew; D016038:Skin Transplantation / Q000276:immunology*; D013154:Spleen / Q000637:transplantation; D014184:Transplantation, Homologous / Q000276:immunology*
D003176:Complement C3; D016207:Cytokines; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007519:Isoantigens; D015847:Interleukin-4