Indonesian medicinal plants. I. Chemical structures of calotroposides A and B, two new oxypregnane-oligoglycosides from the root of Calotropis gigantea (Asclepiadaceae).
Two new oxypregnane-oligoglycosides named calotroposides A (1) and B (2) have been isolated from the root of Calotropis gigantea (Asclepiadaceae), an Indonesian medicinal plant, and their chemical structures have been elucidated by chemical and spectroscopic methods as 12-O-benzoyllineolon 3-O-beta-D-cymaropyranosyl(1----4)-beta-D-oleandropyranosyl( 1----4)- beta-D-oleandropyranosyl(1----4)-beta-D-cymaropyranosyl(1--- -4)-beta-D- cymaropyranoside and 12-O-benzoyldeacetylmetaplexigenin 3-O-beta-D-cymaropyranosyl(1---4)-beta-D-oleandropyranosyl(- ---4)- beta-D-oleandropyranosyl(1----4)-beta-D-cymaropyranosyl(1--- -4)- beta-D-cymaropyranoside, respectively.
Kitagawa
I
I
Faculty of Pharmaceutical Sciences, Osaka University, Japan.
Zhang
R S
RS
Park
J D
JD
Baek
N I
NI
Takeda
Y
Y
Yoshikawa
M
M
Shibuya
H
H
D010277:Parasympathomimetics / Q000138:chemical synthesis* / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D011278:Pregnanes; D012503:Saponins / Q000138:chemical synthesis* / Q000494:pharmacology
D010277:Parasympathomimetics; D011278:Pregnanes; D012503:Saponins; C077813:calotroposide A; C077814:calotroposide B