title: Elevated plasma immunoreactive beta-endorphin in anorexia nervosa.
abstract: Basal morning plasma levels of immunoreactive-beta-endorphin (ir-beta-EP), and 17-beta estradiol (E2) were assessed in 25 adolescents with anorexia nervosa (AN) in comparison to 24 healthy controls. All subjects were drug free for at least 6 weeks. The mean plasma level of ir-beta-EP was significantly higher (84%) in the AN patients when compared with the control subjects. The elevated plasma ir-beta-EP may be relevant to the suppression of appetite, tolerance of fasting, and to the hypothalamic hypogonadism in AN.
authors.affiliation: Department of Obstetrics & Gynecology, Sapir Medical Center, Kfar Saba, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Tepper
authors.forename: A
authors.initials: A
authors.lastname: Weizman
authors.forename: A
authors.initials: A
authors.lastname: Apter
authors.forename: S
authors.initials: S
authors.lastname: Tyano
authors.forename: Y
authors.initials: Y
authors.lastname: Beyth
mesh_terms: D000293:Adolescent; D000328:Adult; D000856:Anorexia Nervosa / Q000097:blood*; D002940:Circadian Rhythm / Q000502:physiology; D004958:Estradiol / Q000097:blood; D005260:Female; D006801:Humans; D001615:beta-Endorphin / Q000097:blood* / Q000276:immunology
chemical_list: D004958:Estradiol; D001615:beta-Endorphin