title: Fel d I allergen: skin and or saliva?
abstract: To determine the relative importance of saliva and sebaceous glands as sources of Fel d I allergen, we compared Fel d I levels at the base and tip of the hair in areas presenting more or less sebaceous glands and areas licked more or less frequently. The amount of Fel d I was significantly higher at the base than the tip of the hair. Further, it was strongly correlated with the density of sebaceous glands. This study demonstrated that the most abundant source of Fel d I allergen is cat skin.
authors.affiliation: Department of Chest Disease and Allergy, Hôpital de Ste-Marguerite, Marseille, France.
authors.forename: P
authors.initials: P
authors.lastname: Mata
authors.forename: D
authors.initials: D
authors.lastname: Charpin
authors.forename: C
authors.initials: C
authors.lastname: Charpin
authors.forename: P
authors.initials: P
authors.lastname: Lucciani
authors.forename: D
authors.initials: D
authors.lastname: Vervloet
mesh_terms: D000485:Allergens / Q000032:analysis*; D000818:Animals; D002415:Cats / Q000276:immunology*; D006023:Glycoproteins; D012463:Saliva / Q000276:immunology*; D012867:Skin / Q000276:immunology*
chemical_list: D000485:Allergens; D006023:Glycoproteins; C059296:Fel d 1 protein, Felis domesticus