Assessment of interleukin-1 activity of peritoneal macrophages in mice infected with Schistosoma mansoni before and after praziquantel administration.
This work was devoted to clarify the changes in interleukin-1 (IL-1) activity of peritoneal macrophages in mice experimentally infected with S. mansoni before and after praziquantel administration. A significant increase in (IL-1) activity after praziquantel administration was detected. These findings clarify the role of praziquantel in improving the immune state of the infected host.
Salem
A E
AE
Department of Parasitology, Medical Research Institute, Alexandria University, Egypt.
Rashwan
E A
EA
Abo-el-Nazar
S Y
SY
D000818:Animals; D002478:Cells, Cultured; D007375:Interleukin-1 / Q000276:immunology*; D008264:Macrophages / Q000276:immunology*; D051379:Mice; D011223:Praziquantel / Q000627:therapeutic use*; D012555:Schistosomiasis mansoni / Q000188:drug therapy / Q000276:immunology*
D007375:Interleukin-1; D011223:Praziquantel