title: Aseptic loosening of the femoral component in cemented total hip replacement.
abstract: The purpose of this study was to identify factors which predispose to aseptic loosening of the femoral component in cemented total hip replacement. Its design was based on rigid selection criteria, so that successful and loose replacements which employed the same surgical technique were compared. Measurements of patient anatomy and of the insertion of the femoral component were made, by an accurate computer technique, on initial post-operative radiographs. Loosening was associated with heavier patients with a wider medullary canal which was flared proximally. This difference in anatomy led to differing distributions of cement in the successful and loose replacements. Medial cement-bone demarcation, at the mid-stem level, was also associated with loosening. These findings indicate the importance of optimizing the size of the prosthesis with respect to the femoral morphology.
authors.affiliation: Department of Medical Biophysics, University of Manchester, UK.
authors.forename: P R
authors.initials: PR
authors.lastname: Jones
authors.forename: D W
authors.initials: DW
authors.lastname: Hukins
authors.forename: M L
authors.initials: ML
authors.lastname: Porter
authors.forename: K E
authors.initials: KE
authors.lastname: Davies
authors.forename: A J
authors.initials: AJ
authors.lastname: Timperley
authors.forename: K
authors.initials: K
authors.lastname: Hardinge
authors.forename: C J
authors.initials: CJ
authors.lastname: Taylor
mesh_terms: D001843:Bone Cements / Q000627:therapeutic use*; D006621:Hip Joint / Q000000981:diagnostic imaging; D006622:Hip Prosthesis / Q000706:statistics & numerical data; D006801:Humans; D011184:Postoperative Period; D011474:Prosthesis Design; D011475:Prosthesis Failure; D011859:Radiography; D012086:Reoperation / Q000706:statistics & numerical data; D012737:Sex Factors
chemical_list: D001843:Bone Cements