Seven Achilles tendinitis including 3 complicated by rupture during fluoroquinolone therapy.
We describe 7 Achilles tendinitis occurring during fluoroquinolone treatment. Antibiotic agents used were pefloxacin and ofloxacin. In 3 cases the course was complicated by rupture of the tendon, one of which is histologically documented. The toxic effects of quinolones on tendon is discussed.
Ribard
P
P
Department of Rheumatology, Medical School Xavier-Bichat, Hôpital Bichat, Paris, France.
Audisio
F
F
Kahn
M F
MF
De Bandt
M
M
Jorgensen
C
C
Hayem
G
G
Meyer
O
O
Palazzo
E
E
D000125:Achilles Tendon / Q000293:injuries* / Q000473:pathology*; D000368:Aged; D000369:Aged, 80 and over; D000890:Anti-Infective Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001991:Bronchitis / Q000188:drug therapy; D003556:Cystitis / Q000188:drug therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015242:Ofloxacin / Q000627:therapeutic use; D015366:Pefloxacin / Q000627:therapeutic use; D012422:Rupture, Spontaneous / Q000139:chemically induced; D013166:Spondylitis / Q000188:drug therapy; D052256:Tendinopathy / Q000150:complications* / Q000473:pathology; D013708:Tendon Injuries / Q000150:complications*
D000890:Anti-Infective Agents; D015366:Pefloxacin; D015242:Ofloxacin