Comparison of the inhibitory effect of sulfamonomethoxine and other sulfonamides on capsule formation of Bordetella bronchiseptica.
The inhibitory effect of sulfamonomethoxine and other sulfonamides on the capsule formation of sulfonamide-resistant Bordetella bronchiseptica was investigated. All the sulfonamides having MeO(-OCH3) groups inhibited the capsule formation of B. bronchiseptica. Strong inhibition was obtained with sulfamonomethoxine. Inhibition was not seen with sulfonamides having no MeO groups.
Kuwano
A
A
Developmental Research Laboratories, Daiichi Pharmaceutical Co., Ltd., Tokyo, Japan.
Ito
T
T
Tachi
H
H
Hiramune
T
T
D016667:Bacterial Capsules / Q000187:drug effects* / Q000502:physiology; D016950:Bordetella bronchiseptica / Q000187:drug effects* / Q000502:physiology; D013422:Sulfamonomethoxine / Q000494:pharmacology*; D013449:Sulfonamides / Q000494:pharmacology*
D013449:Sulfonamides; D013422:Sulfamonomethoxine