title: Diffuse nerve fiber layer loss in normal tension glaucoma.
abstract: 14 eyes of 14 normal tension glaucoma (NTG) patients with the maximum intraocular pressure (IOP) > or = 19 mmHg and 16 eyes of 16 NTG patients with the maximum IOP < 19 mmHg were examined. All patients had a scotoma confined to the upper or lower hemifield. Eyes with the maximum IOP > or = 19 mmHg showed significantly diffuse retinal nerve fiber layer (RNFL) loss in the RNFL area corresponded to the spared visual hemifield as compared to those with the maximum IOP < 19 mmHg. The results suggests that, even in NTG, IOP may be an important factor causing optic nerve damage.
authors.affiliation: Department of Ophthalmology, Nihon University, Tokyo, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Yamazaki
authors.forename: C
authors.initials: C
authors.lastname: Koide
authors.forename: F
authors.initials: F
authors.lastname: Takahashi
authors.forename: H
authors.initials: H
authors.lastname: Yamada
mesh_terms: D005260:Female; D005654:Fundus Oculi; D005901:Glaucoma / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology; D009901:Optic Nerve Diseases / Q000473:pathology; D012164:Retinal Diseases / Q000473:pathology*; D012607:Scotoma / Q000473:pathology; D014794:Visual Fields