Multiple minute marker chromosomes derived from Y identified by FISH in an intersexual infant.
Chromosomal analysis in a child with ambiguous sex showed mosaicism of at least two cell lines with one or more marker chromosomes or none at all. They were shown to be derived from the Y chromosome by fluorescent in situ hybridisation (FISH) using different DNA probes that cover parts of the long and the short arm.
Diekmann
L
L
Städtische Kinderklinik, Dortmund, Federal Republic of Germany.
Palm
K
K
Pfeiffer
R A
RA
Trautmann
U
U
Scholz
W
W
Schroers
E
E
Vogt
P
P
Köhler
M
M
D015342:DNA Probes / Q000235:genetics; D012734:Disorders of Sex Development / Q000235:genetics*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007231:Infant, Newborn; D008297:Male; D009030:Mosaicism / Q000235:genetics*; D014998:Y Chromosome
D015342:DNA Probes