[Reparative changes in the sensorimotor cortex of the offspring in moderate prenatal alcoholism].
Sensorimotor cortex of 21-, 30-, 60-day-old offspring given prenatally moderate alcohol (2 g/kg) manifested signs of compensatory type: double nerve and glial cells, open capillaries, nearby nerve and glial cell bodies with basal membrane of capillaries. Intracellular reparative processes in dystrophic neurons were observed: nuclear activation, hyperplasia of cytoplasmic organelles, hypertrophy of some of them. Reparative processes are more distinct in 30-day-old rat offspring In 60-day-old offspring a polymorphic pattern of cortical synapses ultrastructure was found. However, dystrophic changes of neurons and interneuronal connections still remain.
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D000818:Animals; D002196:Capillaries / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000473:pathology*; D009044:Motor Cortex / Q000473:pathology* / Q000648:ultrastructure; D009474:Neurons / Q000648:ultrastructure; D015388:Organelles / Q000648:ultrastructure; D011247:Pregnancy; D051381:Rats; D013003:Somatosensory Cortex / Q000473:pathology* / Q000648:ultrastructure; D013569:Synapses / Q000648:ultrastructure
Reparativnye izmeneniia v sensomotornoĭ kore potomstva pri umerennoĭ prenatal'noĭ alkogolizatsii.