[The effect of digoxin on the cerebral blood flow in rabbits].
Hydrogen clearance was used in chronic experiments on 10 unrestrained rabbits to study the influence of digoxin (0.1 mg/kg, i. v.) on the time course of changes in the local brain circulation in the sensorimotor, temporal and optic cortex. It has been revealed that digoxin is capable of exerting varying influence on circulation in the above-mentioned regions. Potential mechanisms of the data obtained are under discussion.
Maksimuk
V F
VF
Mikhaĭlov
I B
IB
Gurbanov
I A
IA
D000818:Animals; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D004077:Digoxin / Q000494:pharmacology*; D004567:Electrodes, Implanted; D008297:Male; D009044:Motor Cortex / Q000098:blood supply / Q000187:drug effects; D011817:Rabbits; D013702:Temporal Lobe / Q000098:blood supply / Q000187:drug effects; D013997:Time Factors; D014793:Visual Cortex / Q000098:blood supply / Q000187:drug effects
D004077:Digoxin
Vliianie digoksina na mozgovoĭ krovotok u krolikov.