[Allergic reactions to teniposide (VM-26) in children with neoplasms].
Allergic reactions of dramatic intensity were observed in 5 children treated with Teniposide (VM-26) for acute lymphoblastic leukaemia and histiocytosis X. In the further treatment this drug was replaced with epoxide, a cytostatic agent which is also a podophyllin derivative but in other chemical formulation. In none of these patients the allergic reaction returned.
Wysocki
M
M
Katedra i I Klinika Chorób Dzieci Ak. Med., Bydgoszczy.
Nowaczyk-Michalak
A
A
Pilecki
O
O
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000188:drug therapy*; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy*; D013713:Teniposide / Q000009:adverse effects*
D013713:Teniposide
Reakcje alergiczne na teniposide (VM-26) u dzieci z choroba nowotworowa.