title: UN-1, a murine monoclonal antibody recognizing a human thymocyte undescribed antigen.
abstract: A monoclonal antibody (MoAb), UN-1, specific for a human thymocyte cell surface antigen was produced. The same MoAb recognized in immunofluorescence also cells of the human T line HPB-ALL, while did not bind human peripheral blood cells and cells of some T, B and myeloid lines. Western blotting analysis of thymocyte membranes with MoAb UN-1 revealed a structure with a molecular weight of 150 kDa. Therefore both the pattern of expression and the size of the antigen recognized by MoAb UN-1 did not correspond to any previously described cell surface molecule.
authors.affiliation: Dip. di Med. Sper. e Clin., Catanzaro, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Tassone
authors.forename: H
authors.initials: H
authors.lastname: Bond
authors.forename: P
authors.initials: P
authors.lastname: Bonelli
authors.forename: F
authors.initials: F
authors.lastname: Tuccillo
authors.forename: L
authors.initials: L
authors.lastname: Cecco
authors.forename: A
authors.initials: A
authors.lastname: Lamberti
authors.forename: F
authors.initials: F
authors.lastname: De Lorenzo
authors.forename: M
authors.initials: M
authors.lastname: Cerra
authors.forename: M C
authors.initials: MC
authors.lastname: Turco
authors.forename: S
authors.initials: S
authors.lastname: Venuta
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000954:Antigens, Surface / Q000276:immunology*; D015153:Blotting, Western; D002459:Cell Fusion; D006801:Humans; D051379:Mice; D008807:Mice, Inbred BALB C; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D000954:Antigens, Surface