[Effect of exogenous creatine phosphate on electrophysiologic myocardial parameters in overload heart failure].
Experiments with rats undergoing overload testing showed that exogenous creatine phosphate was likely to fail to penetrate into myocardiocytes and to affect their energy balance directly. However, during its long-term administration in energy deficiency, creatine phosphate was able to maintain cardiac pump function via activation of processes controlling sinus nodal automatism and atrioventricular conduction.
Khanina
N Ia
NIa
Savel'ev
V A
VA
Vikulova
O V
OV
D000818:Animals; D002303:Cardiac Output, Low / Q000503:physiopathology*; D004562:Electrocardiography / Q000187:drug effects; D004594:Electrophysiology; D006321:Heart / Q000187:drug effects* / Q000503:physiopathology; D010725:Phosphocreatine / Q000494:pharmacology*; D051381:Rats
D010725:Phosphocreatine
Vliianie ékzogennogo kreatinfosfata na élektrofiziologicheskie parametry miokarda pri peregruzochnoĭ forme serdechnoĭ nedostatochnosti.