[Morbidity and mortality in type 1 and type 2 diabetes mellitus after the diagnosis of diabetic retinopathy].
One to ten years after laser coagulation for diabetic retinopathy, 229 type I diabetics (mean age 44.3 years) and 157 type II diabetics (mean age 65 years) were re-studied for morbidity and mortality (progression of late damage, duration of survival, cause of death). The duration of diabetes at the first laser coagulation averaged 23.1 years for type I diabetics (15.9 years for type II). Average period from the first laser coagulation to the re-examination was 6.5 years for type I, 5.1 for type II diabetics. Of those patients still alive 6.7% had gone blind (type II: 7.3%). 2.1% and 4.6%, respectively, were receiving dialysis treatment, while renal transplantation had been performed in 3.1 and 1.8%, respectively. Stroke was the most frequent macrovascular complications (8.4 and 16.5%), followed by leg amputation (3.6 and 14.7%) and myocardial infarction (3.7 and 18.3%). 83 patients had died: 35 (15.3%) type I and 48 (30.6%) type II diabetics. Causes of death were septicaemia 14.3% (0%), uraemia 11.4% (8.3%), myocardial infarction 14.3% (33.3%), heart failure 8.6% (29.2%) and stroke 5.7% (6.3%). 10.7% (24.2%) had died within the first 5 years after laser coagulation. Despite a lower incidence of blindness in patients with diabetic retinopathy, the vascular disease progresses in other vascular regions so that a large proportion of diabetics will develop renal failure or die early from macrovascular complications.
Diglas
J
J
Ludwig-Boltzmann-Institut für Stoffwechselerkrankungen und Ernährung, 3. Medizinische Abteilung, Krankenhaus der Stadt Wien-Lainz.
Willinger
C
C
Neu
U
U
Irsigler
K
K
D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000209:etiology; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000401:mortality*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000401:mortality*; D003928:Diabetic Nephropathies / Q000209:etiology; D003930:Diabetic Retinopathy / Q000175:diagnosis* / Q000601:surgery; D005128:Eye Diseases / Q000209:etiology; D005500:Follow-Up Studies; D006801:Humans; D017075:Laser Coagulation; D008875:Middle Aged; D013997:Time Factors
Morbidität und Letalität bei Typ-I-und Typ-II-Diabetikern nach Diagnose einer diabetischen Retinopathie.