Contact sensitivity to flavourings and perfumes in atopic dermatitis.
16 children with atopic dermatitis and 4 nonatopics were skin tested with flavourings and perfumes. Immediate reactions to balsam of Peru and fragrance-mix were found in 9 atopics, and none among nonatopics. An irritant is more probable than an immunologic mechanism. Allergen solutions should probably be assayed at a lower concentration in atopic patients. This study points to a possible aggravating factor from perfumes and flavourings ingested, inhaled, or used as cosmetics.
Abifadel
R
R
Service de Dermatologie, Hôpital des Enfants, Bordeaux, France.
Mortureux
P
P
Perromat
M
M
Ducombs
G
G
Taieb
A
A
D002648:Child; D003876:Dermatitis, Atopic / Q000150:complications*; D003877:Dermatitis, Contact / Q000209:etiology*; D017453:Dermatitis, Irritant / Q000209:etiology; D005148:Facial Dermatoses / Q000139:chemically induced; D005260:Female; D005421:Flavoring Agents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010476:Perfume / Q000009:adverse effects*
D005421:Flavoring Agents; D010476:Perfume