title: Acetylenic glucosides from Microglossa pyrifolia.
abstract: From the leaves of Microglossa pyrifolia Lam. (Asteraceae) four new acetylenic glucosides (1-4) have been isolated. The aglucones 2a and 4a are new polyynes. The aglucone 3a could only be isolated as a mixture of E/Z-isomers in a ratio of 4:1. The structures of 1-4 were elucidated by spectroscopic and biochemical methods. Compound 1 shows antibacterial activity.
authors.affiliation: Pharmazeutisches Institut, Rheinische Friedrich-Wilhelms-Universität Bonn, Federal Republic of Germany.
authors.forename: G
authors.initials: G
authors.lastname: Rücker
authors.forename: S
authors.initials: S
authors.lastname: Kehrbaum
authors.forename: H
authors.initials: H
authors.lastname: Sakulas
authors.forename: B
authors.initials: B
authors.lastname: Lawong
authors.forename: F
authors.initials: F
authors.lastname: Goeltenboth
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D006027:Glycosides