title: Acute secretory travellers' diarrhoea caused by Vibrio cholerae non-01 which does not produce cholera-like or heat-stable enterotoxins.
abstract: An Australian tourist suffering from severe acute watery diarrhoea and dehydration due to Vibrio cholerae non-01 was studied. The V. cholerae strain isolated from the patient belonged to serovar 05. The organism did not produce any of the conventional enterotoxins including cholera-toxin (CT) or heat-stable toxins (NAG-ST) that are known to be associated with intestinal secretion. This report suggests that toxin(s) other than CT-like or NAG-ST may be involved in the pathogenesis of diarrhoea by some V. cholerae non-01 strains.
authors.affiliation: National Institute of Cholera and Enteric Diseases, Beliaghata, Calcutta, India.
authors.forename: S K
authors.initials: SK
authors.lastname: Bhattacharya
authors.forename: M K
authors.initials: MK
authors.lastname: Bhattacharya
authors.forename: T
authors.initials: T
authors.lastname: Ramamurthy
authors.forename: A
authors.initials: A
authors.lastname: Pal
authors.forename: P K
authors.initials: PK
authors.lastname: Bag
authors.forename: T
authors.initials: T
authors.lastname: Takeda
authors.forename: T
authors.initials: T
authors.lastname: Shimada
authors.forename: P
authors.initials: P
authors.lastname: Dutta
authors.forename: A
authors.initials: A
authors.lastname: Debnath
authors.forename: S
authors.initials: S
authors.lastname: Chakraborti
mesh_terms: D000208:Acute Disease; D000328:Adult; D002771:Cholera / Q000382:microbiology*; D002772:Cholera Toxin / Q000096:biosynthesis*; D003967:Diarrhea / Q000382:microbiology*; D004768:Enterotoxins / Q000096:biosynthesis*; D006801:Humans; D008297:Male; D014195:Travel; D014734:Vibrio cholerae / Q000378:metabolism*
chemical_list: D004768:Enterotoxins; C037420:stN protein, Vibrio cholerae; D002772:Cholera Toxin