title: Assessment of interleukin-1 activity of peritoneal macrophages in mice infected with Schistosoma mansoni before and after praziquantel administration.
abstract: This work was devoted to clarify the changes in interleukin-1 (IL-1) activity of peritoneal macrophages in mice experimentally infected with S. mansoni before and after praziquantel administration. A significant increase in (IL-1) activity after praziquantel administration was detected. These findings clarify the role of praziquantel in improving the immune state of the infected host.
authors.affiliation: Department of Parasitology, Medical Research Institute, Alexandria University, Egypt.
authors.forename: A E
authors.initials: AE
authors.lastname: Salem
authors.forename: E A
authors.initials: EA
authors.lastname: Rashwan
authors.forename: S Y
authors.initials: SY
authors.lastname: Abo-el-Nazar
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D007375:Interleukin-1 / Q000276:immunology*; D008264:Macrophages / Q000276:immunology*; D051379:Mice; D011223:Praziquantel / Q000627:therapeutic use*; D012555:Schistosomiasis mansoni / Q000188:drug therapy / Q000276:immunology*
chemical_list: D007375:Interleukin-1; D011223:Praziquantel