[Kinetic characteristics of Ca2+-phospholipid-dependent protein kinase from the rat liver in the early stages after x-ray irradiation].
The changes of kinetic characteristics (apparent Km and Vmax) of the Ca2+ phospholipid-dependent protein kinase (protein kinase C) from the rat liver for substrates ATP and histone Hl 2 and 24 hours after total X-ray irradiation have been established. The obtained results evidence for the important role of these changes in early radiosensitivity of protein kinase C.
Andriĭchuk
T R
TR
Verkhogliad
I N
IN
Tsudzevich
B A
BA
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D006657:Histones / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000201:enzymology / Q000528:radiation effects*; D011493:Protein Kinase C / Q000528:radiation effects*; D051381:Rats; D013997:Time Factors
D006657:Histones; D000255:Adenosine Triphosphate; D011493:Protein Kinase C
Kineticheskie kharakteristiki Ca2+-fosfolipidzavisimoĭ proteinkinazy pecheni krys na rannikh étapakh posle luchevogo vozdeĭstviia.