Glycopeptidolipids--a new class of artificial antigens with carbohydrate determinants. Synthesis of artificial antigen with type-specific oligosaccharide hapten from Neisseria meningitidis group B.
Synthetic lipopeptide N-palmitoyltyrosyl-seryl-seryl-asparaginyl-alanine, an analogue of B-mitogenic tripalmitoyl-pentapeptide from Escherichia coli lipoprotein, was coupled with an oligosaccharide hapten from Neisseria meningitidis lipooligosaccharide to give a glycopeptidolipid conjugate--the artificial antigen of a new type processing the type-specific microbial determinant.
Dmitriev
B A
BA
N.F. Gamaleya Institute for Epidemiology and Microbiology, Moscow, Russia.
Ovchinnikov
M V
MV
Lapina
E B
EB
Pluzhnikova
G N
GN
Lopyrev
I V
IV
Chernyak AYa
D000942:Antigens, Bacterial / Q000737:chemistry* / Q000276:immunology; D002240:Carbohydrate Sequence; D006001:Glycoconjugates / Q000138:chemical synthesis / Q000276:immunology*; D006241:Haptens / Q000276:immunology; D008070:Lipopolysaccharides / Q000276:immunology*; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D009345:Neisseria meningitidis / Q000276:immunology*; D009842:Oligopeptides / Q000276:immunology*
D000942:Antigens, Bacterial; D006001:Glycoconjugates; D006241:Haptens; D008070:Lipopolysaccharides; D009842:Oligopeptides; C078068:N-palmitoyl-tyrosyl-seryl-seryl-asparaginyl-alanine