title: GCWIND: a microcomputer program for identifying open reading frames according to codon positional G+C content.
abstract: GCWIND is a microcomputer (IBM-PC compatible) program for the identification of protein-coding open reading frames. The program is similar to the FRAME program, but the latter has only been implemented for a specialized graphics package. The base compositions (%G+C) for each of the three possible reading phases through the DNA sequence are displayed separately, together with the positions of potential translation initiation and termination codons (on the leading and complementary strands), to provide an immediate representation of those regions within the sequence that have coding potential.
authors.affiliation: Department of Genetics, Trinity College, Dublin, Ireland.
authors.forename: D C
authors.initials: DC
authors.lastname: Shields
authors.forename: D G
authors.initials: DG
authors.lastname: Higgins
authors.forename: P M
authors.initials: PM
authors.lastname: Sharp
mesh_terms: D003062:Codon / Q000032:analysis*; D008838:Microcomputers; D016366:Open Reading Frames; D017422:Sequence Analysis, DNA; D012984:Software
chemical_list: D003062:Codon