title: Morphometry of the Sylvian fissure and the corpus callosum, with emphasis on sex differences.
abstract: The relationship between anatomical asymmetries in the perisylvian region and the sizes of different regions of the corpus callosum was investigated post-mortem in 40 brains of right-handed hospital admissions (20 males, 20 females) with no cortical involvement. There were no sex differences either in anatomical asymmetries or in regional size of the callosum. There was a negative correlation between the absolute value of Sylvian fissure (planum temporale) asymmetries and the size of the isthmus in males but not in females. Further, there was a significant negative correlation between the size of the Sylvian fissure (or planum temporale) and the size of the callosal mid-body in males but not in females. There was no correlation between the asymmetry of the planum temporale magnitude of left-right and total size of the planum (left+right). These findings constrain theories about the ontogenesis of hemispheric specialization through changes in callosal connectivity and about sex differences in interhemispheric organization.
authors.affiliation: Neuropsychiatric Institute, Brain Research Institute, Los Angeles, California.
authors.forename: F
authors.initials: F
authors.lastname: Aboitiz
authors.forename: A B
authors.initials: AB
authors.lastname: Scheibel
authors.forename: E
authors.initials: E
authors.lastname: Zaidel
mesh_terms: D000328:Adult; D000368:Aged; D002540:Cerebral Cortex / Q000033:anatomy & histology; D003337:Corpus Callosum / Q000033:anatomy & histology*; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008297:Male; D008875:Middle Aged; D012727:Sex Characteristics