[Serum N-acetyl-beta-D-glucosaminidase (NAG) activity in patients with diabetes mellitus with reference to diabetic microangiopathy].
In 110 diabetics type I and type II and in 30 control subjects the total serum activity of NAG as well as of its isoenzymatic forms A and B was determined. In cases with diabetic nephropathy the GFR and serum creatinine was also analysed. It was found that NAG activity is correlated to the degree of clinical symptoms of diabetic vascular changes. Therefore it could be suggested that NAG plays a role in development of microangiopathy. NAG determination may also serve as an index differentiating the diabetic microangiopathy from other forms of microvessels.
Gosiewska
A
A
Kliniki Endokrynologii AM, Białymstoku.
Kinalska
I
I
Zarzycki
W
W
Górska
M
M
Borejszo
I
I
D000118:Acetylglucosaminidase / Q000097:blood*; D000328:Adult; D000368:Aged; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000201:enzymology*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000201:enzymology*; D003928:Diabetic Nephropathies / Q000201:enzymology; D003930:Diabetic Retinopathy / Q000201:enzymology* / Q000209:etiology; D004789:Enzyme Activation / Q000502:physiology; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D008297:Male; D008833:Microcirculation / Q000201:enzymology; D008875:Middle Aged; D011507:Proteinuria / Q000201:enzymology
D007527:Isoenzymes; D000118:Acetylglucosaminidase
Aktywność N-acetylo-beta-D-glukozaminidazy (NAG) w surowicy u chorych na cukrzyce z uwzglednieniem mikroangiopatii cukrzycowej.