[Major sickle cell anemia and pregnancy. Systematic prophylactic transfusions. 13 case reports].
The seriousness of sickle cell disease together with pregnancy has led doctors to look for therapies which have yet scarcely shown their worth. Systematic blood transfusions in pregnancy did seem to improve the prognosis for both mother and fetus. Prophylactic transfusion has made it possible for us to carry thirteen pregnancies to term. There was no mortality either of fetus or mother while the morbidity either of fetus or mother while the morbidity was significantly cut down to new pathologies which were easily treated. The absence of any side effects from the transfusions encourages us to contribute this treatment working together with a highly competent blood transfusion bank.
Rhimi
Z
Z
Clinique Universitaire Gynécologique et Obstétricale, Hôpital Saint-Antoine, Paris.
Marpeau
L
L
Achite
N
N
Jault
T
T
Gueltier
X
X
Larue
L
L
Barrat
J
J
D000328:Adult; D000755:Anemia, Sickle Cell / Q000097:blood / Q000453:epidemiology / Q000628:therapy*; D001803:Blood Transfusion / Q000379:methods / Q000592:standards*; D005260:Female; D005500:Follow-Up Studies; D006785:Hospitals, University; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D008428:Maternal Mortality; D010297:Paris / Q000453:epidemiology; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood / Q000453:epidemiology / Q000628:therapy*; D011256:Pregnancy Outcome; D011322:Primary Prevention / Q000379:methods; D011379:Prognosis
Drépanocytose majeure et grossesse. Transfusions prophylactiques systématiques. A propos de 13 cas.