title: Preparation of potential anti-inflammatory agents from dehydroabietic acid.
abstract: Methyl 16-nor-16-carboxydehydroabietate (22), 16-nor-16-carboxydehydroabietinol acetate (23), methyl 7-keto-16-nor-16-carboxydehydroabietate (29), 16-nor-16-carboxydehydroabietic acid (30), 16-nor-16-carboxydehydroabietinol (31), 7-keto-16-nor-16-carboxydehydroabietic acid (32), methyl 7-hydroxy-16-nor-16-carboxydehydroabietate (33), and 7-hydroxy-16-nor-16-carboxydehydroabietic acid (34) were prepared from dehydroabietic acid. Only 22 and 32 had weak anti-inflammatory activity.
authors.affiliation: Department of Agricultural Chemistry, National Pingtung Institute of Agriculture, Taiwan, Republic of China.
authors.forename: W S
authors.initials: WS
authors.lastname: Li
authors.forename: J D
authors.initials: JD
authors.lastname: McChesney
mesh_terms: D045784:Abietanes; D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000302:isolation & purification*; D004224:Diterpenes / Q000032:analysis*
chemical_list: D045784:Abietanes; D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D004224:Diterpenes; C013913:dehydroabietic acid