title: Depressed patients with dysfunctional families: description and course of illness.
abstract: Sixty-eight depressed patients were subdivided according to their family's level of family functioning into functional and dysfunctional groups. Patients from dysfunctional families did not differ from those from functional families on measures of severity of depression, chronicity of depression, depression subtypes, other nonaffective psychiatric diagnoses, history of depression, or neuroendocrine functioning. Patients from dysfunctional families did have significantly higher levels of neuroticism. A 12-month follow-up of these patients indicated that depressed patients with dysfunctional families had a significantly poorer course of illness, as manifested by higher levels of depression, lower levels of overall adjustment, and a lower proportion of recovered patients. Thus, impaired family functioning appears to be an important prognostic factor in major depression.
authors.affiliation: Department of Psychiatry and Human Behavior, Brown University, Providence, Rhode Island.
authors.forename: I W
authors.initials: IW
authors.lastname: Miller
authors.forename: G I
authors.initials: GI
authors.lastname: Keitner
authors.forename: M A
authors.initials: MA
authors.lastname: Whisman
authors.forename: C E
authors.initials: CE
authors.lastname: Ryan
authors.forename: N B
authors.initials: NB
authors.lastname: Epstein
authors.forename: D S
authors.initials: DS
authors.lastname: Bishop
mesh_terms: D000328:Adult; D003866:Depressive Disorder / Q000523:psychology*; D005190:Family / Q000523:psychology*; D005260:Female; D005500:Follow-Up Studies; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D010552:Personality Assessment / Q000706:statistics & numerical data*; D011594:Psychometrics; D015203:Reproducibility of Results; D012931:Social Environment