The effect of exercise on levodopa absorption.
We studied the effect of exercise using cycle ergometry on levodopa absorption in ten patients with Parkinson's disease. Oral levodopa was administered during exercise and at rest on separate days. Exercise delayed levodopa absorption in five patients, increased it in three, and did not influence it in two. We conclude that exercise can either increase or decrease levodopa absorption.
Carter
J H
JH
Department of Neurology, School of Medicine, Oregon Health Sciences University, Portland 97201.
Nutt
J G
JG
Woodward
W R
WR
D000042:Absorption; D000368:Aged; D005260:Female; D006801:Humans; D007980:Levodopa / Q000493:pharmacokinetics*; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000378:metabolism* / Q000503:physiopathology; D005082:Physical Exertion; D010809:Physical Fitness; D015203:Reproducibility of Results
D007980:Levodopa