title: [Antioxidant effect of dimethyl sulfoxide in acute liver injury by carbon tetrachloride].
abstract: After subcutaneous administration of dimethyl sulfoxide into rats with toxic, tetrachloromethane-produced impairment of liver tissue, lipid peroxidation was effectively inhibited in hepatocytes and the state of anti-oxidation system was improved. Antioxidative properties of dimethyl sulfoxide were shown also in vitro.
authors.forename: Ia I
authors.initials: IaI
authors.lastname: Gonskiĭ
authors.forename: M M
authors.initials: MM
authors.lastname: Korda
authors.forename: I N
authors.initials: IN
authors.lastname: Klishch
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology* / Q000627:therapeutic use; D002252:Carbon Tetrachloride Poisoning / Q000188:drug therapy*; D004121:Dimethyl Sulfoxide / Q000494:pharmacology* / Q000627:therapeutic use; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D008297:Male; D051381:Rats
chemical_list: D000975:Antioxidants; D004121:Dimethyl Sulfoxide
vernacular_title: Antiokislitel'noe deĭstvie dimtilsul'foksida pri ostrom porazhenii pecheni tetrakhlormetanom.