Biological activities of human interferon and 2'-5' oligoadenylates in plants.
Exogenous human interferon 2 (IFN) and 2'-5' oligoadenylates (2-5A) have been shown to cause at least a dual physiological effect in tobacco and wheat: (i) increased cytokinin activity and (ii) induced synthesis of numerous proteins, among which members of two groups of stress proteins have been identified, namely pathogenesis-related (PR) and heat shock (HS) proteins. These effects were observed only by low concentrations of these substances: IFN at 0.1-1 u/ml and 2-5A at 1-10 nM.
Kulaeva
O N
ON
Department of Virology, Moscow State University, USSR.
Fedina
A B
AB
Burkhanova
E A
EA
Karavaiko
N N
NN
Karpeisky MYa
Kaplan
I B
IB
Taliansky
M E
ME
Atabekov
J G
JG
D000227:Adenine Nucleotides / Q000494:pharmacology*; D003583:Cytokinins / Q000096:biosynthesis; D006360:Heat-Shock Proteins / Q000096:biosynthesis; D007371:Interferon-gamma / Q000494:pharmacology*; D009843:Oligoribonucleotides / Q000494:pharmacology*; D010940:Plant Proteins / Q000096:biosynthesis*; D010944:Plants / Q000187:drug effects*; D010947:Plants, Toxic; D014176:Protein Biosynthesis / Q000187:drug effects; D014026:Nicotiana / Q000187:drug effects; D014908:Triticum / Q000187:drug effects
D000227:Adenine Nucleotides; D003583:Cytokinins; D006360:Heat-Shock Proteins; D009843:Oligoribonucleotides; D010940:Plant Proteins; C053376:pathogenesis-related proteins, plant; C023505:2',5'-oligoadenylate; D007371:Interferon-gamma