title: Molecular characterization of "inverted" pericentromeric heterochromatin of chromosome 3.
abstract: Inversion of the pericentromeric region of human chromosome 3 [inv (3) (p11q11.2)] is a rare event. Initially, this inversion was identified with staining for Q-bands by fluorescence using quinacrine (QFQ) and later characterized with staining for C-bands by CBG technique. The molecular methods of fluorescence in situ hybridization (FISH) and AluI/Giemsa and TaqI/Giemsa techniques were utilized. The findings suggest that the variable band q11.2 on chromosome 3 contains alphoid DNA sequences, which appear to be similar to those identified by conventional methods in the centromeric region (band p11).
authors.affiliation: Division of Genetics, Long Island College Hospital, SUNY Health Science Center, Brooklyn 11201.
authors.forename: R A
authors.initials: RA
authors.lastname: Conte
authors.forename: S
authors.initials: S
authors.lastname: Luke
authors.forename: R S
authors.initials: RS
authors.lastname: Verma
mesh_terms: D000293:Adolescent; D002503:Centromere / Q000737:chemistry*; D002871:Chromosome Banding; D002893:Chromosomes, Human, Pair 3 / Q000737:chemistry* / Q000502:physiology; D004247:DNA / Q000235:genetics; D006570:Heterochromatin / Q000737:chemistry*; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic / Q000235:genetics
chemical_list: D006570:Heterochromatin; D004247:DNA