[Effect of hemosorption on microcirculation, humoral autoimmunity and lipid peroxidation in patients with stable angina pectoris].
Microhemo- and lymphocirculation, capillary permeability, humoral autoimmunity and lipid peroxidation were determined in 46 patients with Functional Classes III-IV stable angina concurrent with multiple atherosclerotic coronary lesions 24 hours following the second hemosorption session. The clinical efficiency of hemosorption was observed in 47.8% of patients with stenotic coronary atherosclerosis refractory to antianginal therapy. In this group of patients, hemosorption led to accelerated microcirculation, increased microcirculatory reserve potentials and decreased microvascular resistance at rest and in reactive postischemic hyperemia. In patients with abnormal humoral autoimmunity and lipid peroxidation, hemosorption resulted in their hormalization.
Atroshchenko
E S
ES
Shagusultanov
E R
ER
Karpova
I S
IS
Cheshchevik
A B
AB
Kalinina
L M
LM
D000787:Angina Pectoris / Q000276:immunology / Q000503:physiopathology / Q000628:therapy*; D001323:Autoantibodies / Q000096:biosynthesis*; D004351:Drug Resistance; D006464:Hemoperfusion; D006801:Humans; D015227:Lipid Peroxidation / Q000502:physiology*; D008297:Male; D008833:Microcirculation / Q000502:physiology*; D008875:Middle Aged; D014665:Vasodilator Agents / Q000627:therapeutic use
D001323:Autoantibodies; D014665:Vasodilator Agents
Vliianie gemosorbtsii na sostoianie mikrotsirkuliatsii, gumoral'nogo autoimmuniteta i perekisnoe okislenie lipidov u bol'nykh so stabil'noĭ stenokardieĭ.