title: Prevalence of carotid atherosclerosis in diabetic patients. Ultrasound high-resolution B-mode imaging on carotid arteries.
abstract: OBJECTIVE
  To quantitatively assess atherosclerosis of the carotid artery in subjects with and without diabetes.
  
  
  METHODS
  Ultrasound high resolution B-mode imaging of carotid arteries was conducted on 71 nondiabetic subjects without hyperlipidemia or hypertension and 295 diabetic patients to determine IMT of the arterial wall.
  
  
  RESULTS
  IMT was linearly related with age in nondiabetic (IMT = [0.0087 x age] + 0.3318) and diabetic subjects (IMT = [0.0155 x age] + 0.32450). The regression coefficient for age was significantly greater in diabetic than nondiabetic subjects. IMT (mean +/- SD) of diabetic subjects aged 20-29 was significantly greater than that of nondiabetic subjects aged 20-29 (0.73 +/- 0.27 vs. 0.52 +/- 0.07 mm, P less than 0.01). Multivariate regression analysis of 275 NIDDM patients indicated smoking, hyperlipidemia, duration of diabetes, hypertension, and age were factors determining thickness of the carotid arterial wall.
  
  
  CONCLUSIONS
  Diabetes, along with age, hyperlipidemia, smoking, and hypertension, aggravates carotid atherosclerosis.
authors.affiliation: First Department of Medicine, Osaka University Medical School, Japan.
authors.forename: R
authors.initials: R
authors.lastname: Kawamori
authors.forename: Y
authors.initials: Y
authors.lastname: Yamasaki
authors.forename: H
authors.initials: H
authors.lastname: Matsushima
authors.forename: H
authors.initials: H
authors.lastname: Nishizawa
authors.forename: K
authors.initials: K
authors.lastname: Nao
authors.forename: H
authors.initials: H
authors.lastname: Hougaku
authors.forename: H
authors.initials: H
authors.lastname: Maeda
authors.forename: N
authors.initials: N
authors.lastname: Handa
authors.forename: M
authors.initials: M
authors.lastname: Matsumoto
authors.forename: T
authors.initials: T
authors.lastname: Kamada
mesh_terms: D001161:Arteriosclerosis / Q000097:blood / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D001794:Blood Pressure; D002339:Carotid Arteries / Q000000981:diagnostic imaging*; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003920:Diabetes Mellitus / Q000097:blood / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003925:Diabetic Angiopathies / Q000097:blood / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D014280:Triglycerides / Q000097:blood; D014463:Ultrasonography
chemical_list: D002784:Cholesterol; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D006442:Glycated Hemoglobin; D014280:Triglycerides