An antidepressant principle of Lobelia inflata L. (Campanulaceae).
A crude methanolic extract of the leaves of Lobelia inflata exhibited antidepressant activity in mice. The extract was fractionated, monitored by the activity, to give beta-amyrin palmitate as an active component.
Subarnas
A
A
Pharmaceutical Institute, Tohoku University, Sendai, Japan.
Oshima
Y
Y
Sidik
Ohizumi
Y
Y
D000818:Animals; D000928:Antidepressive Agents / Q000302:isolation & purification* / Q000494:pharmacology; D007099:Imipramine / Q000494:pharmacology; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009828:Oleanolic Acid / Q000031:analogs & derivatives; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D014315:Triterpenes / Q000302:isolation & purification* / Q000494:pharmacology
D000928:Antidepressive Agents; D010936:Plant Extracts; D014315:Triterpenes; D009828:Oleanolic Acid; C036380:beta-amyrin; D007099:Imipramine