Weyers' ulnar ray/oligodactyly syndrome and the association of midline malformations with ulnar ray defects.
We describe a two generation family with variable ulnar and radial ray reduction and midline craniofacial abnormalities. The features suggest a diagnosis of Weyers' ulnar ray/oligodactyly syndrome originally described in two isolated cases. Syndromes of ulnar ray reduction are briefly reviewed and the relationship between limb bud and midline development discussed.
Turnpenny
P D
PD
Medical Genetics, Medical School, Foresterhill, Aberdeen.
Dean
J C
JC
Duffty
P
P
Reid
J A
JA
Carter
P
P
D000015:Abnormalities, Multiple / Q000235:genetics*; D000293:Adolescent; D005121:Extremities / Q000196:embryology; D005260:Female; D005385:Fingers / Q000002:abnormalities*; D006228:Hand Deformities, Congenital / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010375:Pedigree; D011884:Radius / Q000002:abnormalities*; D013577:Syndrome; D014071:Tooth Abnormalities / Q000235:genetics*; D014457:Ulna / Q000002:abnormalities*