title: [Diagnosis of infection in full-term infants born after prolonged status of ruptured membranes: clinical observation is sufficient].
abstract: We retrospectively studied our strategy in 80 full-term newborns, born more than 24 hours after rupture of amniotic membranes. Six patients developed clinical signs of sepsis, in four of them sepsis was proven by a positive blood culture. In all cases, clinical symptoms were the first sign of infection. Routine laboratory tests (CRP, leucocyte counts and differentiation, thrombocyte counts) and microbiological investigations (surface cultures, cord blood cultures) were not helpful for the diagnosis of infection at an early stage. These findings are in accordance with the literature. We conclude that after prolonged rupture of membranes with full-term newborns postnatal paediatric care can be limited to a close observation period of 48 hours. There is no need for any further routine investigation of infants without clinical signs of infection.
authors.affiliation: Universiteitskliniek Wilhelmina Kinderziekenhuis, afd Kindergeneeskunde, Utrecht.
authors.forename: C K
authors.initials: CK
authors.lastname: van der Ent
authors.forename: K F
authors.initials: KF
authors.lastname: Joosten
authors.forename: A W
authors.initials: AW
authors.lastname: Tielens
authors.forename: L J
authors.initials: LJ
authors.lastname: Gerards
mesh_terms: D001424:Bacterial Infections / Q000175:diagnosis*; D001772:Blood Cell Count; D001798:Blood Proteins / Q000737:chemistry; D005321:Extraembryonic Membranes; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007743:Labor, Obstetric; D008828:Microbiological Techniques; D011247:Pregnancy; D012189:Retrospective Studies; D013997:Time Factors
chemical_list: D001798:Blood Proteins
vernacular_title: Infectiediagnostiek bij à terme pasgeborenen na langdurig gebroken vruchtvliezen: klinische observatie is voldoende.