Frequency of hepatitis B, C and D and human immunodeficiency virus infections in multi-transfused thalassemics.
Of forty multi-transfused thalassemia patients (26 males, 14 females; mean age 8.1 +/- 5.3 years, range 1-35) with no clinical or biochemical evidence of liver disease, HBsAg, anti-hepatitis C virus and anti-human immunodeficiency virus antibodies were present in 18 (45%), 7 (17.5%) and 1 (2.5%) cases respectively. Three of the 18 (16.7%) HBsAg positive patients were anti-delta antibody positive. Our results indicate that more than 50% of multi-transfused thalassemia patients show serological evidence of one or more of hepatitis B, C and D and human immunodeficiency virus infection.
Amarapurkar
D N
DN
Department of Gastroenterology, BYL Nair Ch Hospital, Bombay.
Kumar
A
A
Vaidya
S
S
Murti
P
P
Bichile
S K
SK
Kalro
R H
RH
Desai
H G
HG
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D015483:HIV Antibodies / Q000032:analysis; D015658:HIV Infections / Q000453:epidemiology* / Q000276:immunology; D006508:Hepatitis Antibodies / Q000032:analysis; D006509:Hepatitis B / Q000276:immunology; D006526:Hepatitis C / Q000276:immunology; D003699:Hepatitis D / Q000276:immunology; D006525:Hepatitis, Viral, Human / Q000453:epidemiology* / Q000276:immunology; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D008297:Male; D013789:Thalassemia / Q000276:immunology / Q000628:therapy*; D065227:Transfusion Reaction
D015483:HIV Antibodies; D006508:Hepatitis Antibodies