[The indices of thrombocyte coagulating and fibrinolytic activity in rheumatoid arthritis patients].
Blood coagulation values (thrombocyte count, adhesive-aggregation thrombocytic activity, coagulographic data) were analysed in 90 patients with rheumatoid arthritis (RA). Increase of plasma coagulation activity was observed in all coagulation activity grades. The anticoagulation activity was most pronounced in grade III RA activity. Thrombocytes of RA patients possessed procoagulant properties and lost significantly their fibrinolytic activity most expressed in grade II RA. This increased the thrombophilic tendency of the plasma potential creating favourable conditions for intravascular coagulation and microthrombus formation, resulting in deterioration of the rheological properties of the blood and the course of the rheumatoid synovitis.
Amosova
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EN
Poroshenko
M A
MA
D000328:Adult; D001172:Arthritis, Rheumatoid / Q000097:blood*; D001777:Blood Coagulation; D001792:Blood Platelets / Q000502:physiology*; D005260:Female; D005342:Fibrinolysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D010979:Platelet Function Tests
Pokazateli svertyvaiushcheĭ i fibrinoliticheskoĭ aktivnosti trombotsitov u bol'nykh revmatoidnym artritom.