Acute isoniazid poisoning.
We present two cases of acute isoniazid poisoning in patients who ingested 7.5 g and 5.0 g of isoniazid respectively, with the intention of committing suicide. Both were admitted unconscious, with ventilatory insufficiency and convulsions. Hepatic dysfunction and peripheral neuropathy were notable complications.
Gurnani
A
A
Department of Anaesthesiology, University College of Medical Sciences, Delhi, India.
Chawla
R
R
Kundra
P
P
Bhattacharya
A
A
D000208:Acute Disease; D000328:Adult; D003975:Diazepam / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007385:Intermittent Positive-Pressure Ventilation; D007538:Isoniazid / Q000506:poisoning*; D008297:Male; D011736:Pyridoxine / Q000627:therapeutic use; D013406:Suicide, Attempted; D013874:Thiopental / Q000627:therapeutic use
D013874:Thiopental; D011736:Pyridoxine; D003975:Diazepam; D007538:Isoniazid