title: [Indium-111 or Tc-99m-HMPAO marked granulocytes as specific markers of florid stage endocarditis--results comparing clinical, histological and scintigraphic findings in 30 patients with suspected endocarditis].
abstract: Thirty patients with clinically suspected infective endocarditis were scanned with Indium-111- or Tc-99m-HM-PAO-labeled granulocytes. The scans were correlated with the clinical course, and in 20 cases with the results from histologic examination of the valves. In six cases the scintigraphic examination gave correct positive results, in three cases false negative, in one case a false positive, and in 20 cases correct negative results. If we limit the analysis to only the histologically proven cases, our data suggest a specificity of the method of 86% and a sensitivity of about 67%.
authors.affiliation: Zentrum für Innere Medizin, Universitätsklinik Marburg.
authors.forename: U
authors.initials: U
authors.lastname: Borst
authors.forename: W
authors.initials: W
authors.lastname: Becker
authors.forename: B
authors.initials: B
authors.lastname: Maisch
authors.forename: W
authors.initials: W
authors.lastname: Börner
authors.forename: K
authors.initials: K
authors.lastname: Kochsiek
mesh_terms: D000038:Abscess / Q000000981:diagnostic imaging / Q000276:immunology; D004452:Echocardiography; D004697:Endocarditis, Bacterial / Q000000981:diagnostic imaging* / Q000276:immunology; D006098:Granulocytes / Q000276:immunology; D006350:Heart Valve Prosthesis; D006351:Heart Valves / Q000000981:diagnostic imaging; D006801:Humans; D007089:Image Enhancement; D007205:Indium Radioisotopes; D007958:Leukocyte Count; D015609:Organotechnetium Compounds; D010091:Oximes; D011877:Radionuclide Imaging; D018805:Sepsis / Q000000981:diagnostic imaging / Q000276:immunology; D019690:Technetium Tc 99m Exametazime
chemical_list: D007205:Indium Radioisotopes; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime
vernacular_title: Indium-111-oder Tc-99m-HMPAO-markierte Granulozyten als spezifische Marker im floriden Stadium der Endokarditis--Ergebnisse im Vergleich klinischer, histologischer und szintigraphischer Befunde bei 30 Patienten unter Endokarditisverdacht.