[Association of proteinases with histones from rat thymus nuclei].
Histone H2A, H2B, and H1--specific proteinases tightly associated with histones were shown to be present in rat thymus nuclei. The activity of proteinases tightly associated with histones increases after exposure of animals to gamma-rays. The denatured DNA activated the histone H1-specific proteinase. These proteinase dissociated from histones in the presence of dithiothreitol. The histones and proteinases were divided into fractions by chromatography on DEAE-cellulose in the presence of 5 mM dithiothreitol.
Gaziev
A I
AI
Kutsyĭ
M P
MP
Zakrzhevskaia
D T
DT
D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism*; D002848:Chromatography, DEAE-Cellulose; D004247:DNA / Q000378:metabolism; D004229:Dithiothreitol; D010450:Endopeptidases / Q000378:metabolism*; D006657:Histones / Q000378:metabolism*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013950:Thymus Gland / Q000378:metabolism*
D006657:Histones; D004247:DNA; D010450:Endopeptidases; D004229:Dithiothreitol
Assotsiatsiia proteinaz s gistonami iader timusa krys.