title: Influence of low dissolved oxygen concentration in body fluid on corrosion fatigue behaviors of implant metals.
abstract: In their previous study, the authors carried out a fatigue test for AISI 316, 316L stainless steels and COP1 alloy in a living animal body and observed a remarkable deterioration in the fatigue durability of these metals. In that study, it was concluded that the reason the corrosion resistance of the metals was reduced in the living body was that the low concentration of dissolved oxygen gas in the body fluid (the partial pressure pO2; 28-78 mmHg) was insufficient to form the chromium oxide passivation film on the metal surface, and the base metal (iron) was released into the environmental fluid in ionic form. In this paper, with the concentration of dissolved oxygen gas in a physiological normal saline solution being set equivalent to that of living body fluid, fatigue tests on AISI 316 were made to simulate the stress corrosion behavior of the metal in the living body. As a result, remarkable deterioration of fatigue strength was observed in the low O2 concentrated normal saline solution, which was the same as that in the living animal body.
authors.affiliation: Department of Biomedical Engineering, School of Medicine, Kitasato University, Kanagawa, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Morita
authors.forename: T
authors.initials: T
authors.lastname: Sasada
authors.forename: I
authors.initials: I
authors.lastname: Nomura
authors.forename: Y Q
authors.initials: YQ
authors.lastname: Wei
authors.forename: Y
authors.initials: Y
authors.lastname: Tsukamoto
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001826:Body Fluids / Q000737:chemistry*; D003343:Corrosion; D066298:In Vitro Techniques; D008422:Materials Testing; D008670:Metals / Q000737:chemistry*; D010100:Oxygen / Q000737:chemistry*; D019736:Prostheses and Implants; D011817:Rabbits
chemical_list: D001672:Biocompatible Materials; D008670:Metals; D010100:Oxygen