Hyperprolactinemia in a patient with Sheehan's syndrome.
I have reported the case of a woman with Sheehan's syndrome who had hyperprolactinemia rather than prolactin deficiency. The patient showed no increase in serum thyrotropin in response to TRH challenge and failed to show a normal increase in serum GH and cortisol after insulin-induced hypoglycemia. A blunted FSH response to LH-RH stimulation was also found. A CT scan of the sella showed no adenoma. The patient responded to prednisolone and thyroxine replacement therapy. When, a few months later, the dose of thyroxine was reduced to a suboptimal level, the hyperprolactinemia recurred.
Kelestimur
F
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Department of Internal Medicine, Medical Faculty, Erciyes University, Kayseri, Turkey.
D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D013006:Growth Hormone / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D006966:Hyperprolactinemia / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D007018:Hypopituitarism / Q000150:complications* / Q000473:pathology; D007511:Ischemia / Q000150:complications* / Q000473:pathology; D007986:Luteinizing Hormone / Q000097:blood; D008875:Middle Aged; D006473:Postpartum Hemorrhage / Q000150:complications*; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D011247:Pregnancy; D011388:Prolactin / Q000097:blood; D011644:Puerperal Disorders / Q000150:complications* / Q000473:pathology; D013577:Syndrome; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000008:administration & dosage / Q000627:therapeutic use
D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin; D013006:Growth Hormone; D011239:Prednisolone; D013974:Thyroxine; D006854:Hydrocortisone