The management of a case of treatment-resistant paraphilia with a long-acting LHRH agonist.
A patient with multiple paraphilias who had been treated for several years with sex drive reducing agents (cyproterone acetate and medroxyprogesterone acetate) with little effect on sexual activity or fantasy was offered treatment with long-acting leuprolide acetate, on LHRH agonist. This produced a marked decrease in all reported sexual thoughts and activities with no significant side-effects.
Dickey
R
R
Gender Identity Clinic, Clarke Institute of Psychiatry, Toronto, Ontario.
D000328:Adult; D003692:Delayed-Action Preparations; D006801:Humans; D007279:Injections, Subcutaneous; D016729:Leuprolide / Q000008:administration & dosage*; D007989:Libido / Q000187:drug effects / Q000502:physiology; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D010262:Paraphilic Disorders / Q000097:blood / Q000188:drug therapy* / Q000523:psychology; D010378:Pedophilia / Q000097:blood / Q000188:drug therapy* / Q000523:psychology; D011388:Prolactin / Q000097:blood; D013739:Testosterone / Q000097:blood
D003692:Delayed-Action Preparations; D013739:Testosterone; D011388:Prolactin; D007986:Luteinizing Hormone; D016729:Leuprolide