title: [Analysis of the role of calcium in analgesic action of non-narcotic analgesics and calcium channel blockers].
abstract: In the mice hot-plate test we have compared analgesic effect of calcium channel blockers and new non-narcotic analgesic antiinflammatory agent PV-107: verapamil > fenigidin > PV-107. Simultaneously we have shown strong correlation (r - 0.82) between analgesic effect and 45Ca2+ efflux of cardiac membrane in depolarizing media in vitro.
authors.forename: F P
authors.initials: FP
authors.lastname: Trinus
authors.forename: M D
authors.initials: MD
authors.lastname: Kurskiĭ
authors.forename: Iu I
authors.initials: IuI
authors.lastname: Gubskiĭ
authors.forename: T A
authors.initials: TA
authors.lastname: Bukhtiarova
mesh_terms: D000700:Analgesics; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D002118:Calcium / Q000378:metabolism / Q000502:physiology*; D002121:Calcium Channel Blockers / Q000494:pharmacology*; D008297:Male; D051379:Mice; D009543:Nifedipine / Q000494:pharmacology; D010147:Pain Measurement; D013997:Time Factors; D014700:Verapamil / Q000494:pharmacology
chemical_list: D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D002121:Calcium Channel Blockers; D014700:Verapamil; D009543:Nifedipine; D002118:Calcium
vernacular_title: Analiz roli kal'tsiia v obezbolivaiushchem deĭstvii nenarkoticheskikh anal'getikov i blokatorov kal'tsievykh kanalov.