title: Comparison of the effects on lipoproteins and apolipoproteins of a diet high in monounsaturated fatty acids, enriched with avocado, and a high-carbohydrate diet.
abstract: A randomized trial was conducted to compare effects of a diet high in monounsaturated fatty acids, enriched with avocado (AE), and a high-complex-carbohydrate diet (AHA-III) on blood lipid concentrations. Fifteen females between 37 and 58 y of age were allocated either to AE followed by AHA-III, or vice versa. Each dietary phase lasted 3 wk. Both diets were found to lower total cholesterol compared with baseline values. AE was more effective, with an 8.2% decrease (P less than 0.05) whereas AHA-III was associated with a 4.9% decrease (NS). Low-density-lipoprotein cholesterol and apolipoprotein B decreased significantly on AE but not on AHA-III (P less than 0.05). The high-density-lipoprotein (HDL) concentration did not change on AE but decreased 13.9% on AHA-III (P less than 0.01). It is concluded that AE is more effective than is AHA-III in decreasing total cholesterol, and, unlike AHA-III, it does not decrease HDL concentrations.
authors.affiliation: Dietary Department, Wesley Hospital, Brisbane, Queensland, Australia.
authors.forename: D M
authors.initials: DM
authors.lastname: Colquhoun
authors.forename: D
authors.initials: D
authors.lastname: Moores
authors.forename: S M
authors.initials: SM
authors.lastname: Somerset
authors.forename: J A
authors.initials: JA
authors.lastname: Humphries
mesh_terms: D000328:Adult; D001053:Apolipoproteins / Q000378:metabolism*; D001055:Apolipoproteins B / Q000378:metabolism; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D004040:Dietary Carbohydrates / Q000008:administration & dosage*; D004041:Dietary Fats / Q000008:administration & dosage*; D005229:Fatty Acids, Monounsaturated / Q000008:administration & dosage*; D005260:Female; D005638:Fruit; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008875:Middle Aged
chemical_list: D001053:Apolipoproteins; D001055:Apolipoproteins B; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D005229:Fatty Acids, Monounsaturated; D008074:Lipoproteins; D002784:Cholesterol