[A simple method of continuous passage of human tumors in immunocompetent mice].
A simple procedure is described for the continuous passage of a human tumor in immunocompetent mice. The BRO human melanoma was transplanted consecutively 25 times by implanting tumor tissue under the sub--renal capsule of mice which had been immunosuppressed by a single dose of whole--body irradiation or by cytosine arabinoside followed by irradiation. The tumor grew continuously for 14 days, and cytological examination showed that the growth consisted almost entirely of tumor cells.
Lokshin
A
A
Riabkova
V I
VI
Sokolova
V K
VK
D000818:Animals; D003561:Cytarabine / Q000494:pharmacology; D006801:Humans; D007121:Immunocompetence; D007165:Immunosuppression Therapy; D008546:Melanoma, Experimental / Q000276:immunology / Q000473:pathology; D051379:Mice; D008810:Mice, Inbred C57BL; D013997:Time Factors; D014183:Transplantation, Heterologous; D014407:Tumor Cells, Cultured / Q000276:immunology / Q000473:pathology; D014916:Whole-Body Irradiation
D003561:Cytarabine
Prostoĭ metod dlia postoiannogo vyrashchivaniia opukholi cheloveka u immunokompetentnykh mysheĭ.