Localization of the human GM-CSF receptor beta chain gene (CSF2RB) to chromosome 22q12.2-->q13.1.
The gene for the beta-chain of the human GM-CSF receptor (CSF2RB) has been mapped to chromosome 22 by PCR analysis of a series of human x rodent somatic cell hybrids. In situ hybridization to normal human chromosomes and two translocations involving chromosome 22 and the chromosome expressing the rare fragile site FRA22A place the gene in the region 22q12.2-->q13.1, proximal to the fragile site.
Shen
Y
Y
Department of Cytogenetics and Molecular Genetics, Adelaide Children's Hospital, North Adelaide, South Australia.
Baker
E
E
Callen
D F
DF
Sutherland
G R
GR
Willson
T A
TA
Rakar
S
S
Gough
N M
NM
D002892:Chromosomes, Human, Pair 22; D006801:Humans; D006822:Hybrid Cells; D017404:In Situ Hybridization, Fluorescence; D015345:Oligonucleotide Probes / Q000235:genetics; D016133:Polymerase Chain Reaction; D016187:Receptors, Granulocyte-Macrophage Colony-Stimulating Factor / Q000235:genetics*; D014178:Translocation, Genetic / Q000235:genetics*
D015345:Oligonucleotide Probes; D016187:Receptors, Granulocyte-Macrophage Colony-Stimulating Factor