title: Comparison of gallbladder ejection fraction with histopathologic changes in acalculous biliary disease.
abstract: This selective retrospective study was undertaken to establish whether the gallbladder contraction (ejection fraction) calculated during cholescintigraphy correlates with the histopathologic changes in the surgical specimen. The medical records of 243 patients who underwent hepatobiliary scintigraphy were reviewed. Of these, 215 patients had cholecystokinin cholescintigraphy and 100 went on to cholecystectomy. The original histologic slides from 67 gallbladders were available and reviewed by a pathologist who graded each specimen based on presence and severity of changes associated with "chronic" cholecystitis. There was no significant correlation between the severity of histopathologic change and cholecystokinin-induced gallbladder emptying.
authors.affiliation: St. Joseph's Hospital, Fort Wayne, Indiana.
authors.forename: J R
authors.initials: JR
authors.lastname: DeCamp
authors.forename: K
authors.initials: K
authors.lastname: Tabatowski
authors.forename: D S
authors.initials: DS
authors.lastname: Schauwecker
authors.forename: A
authors.initials: A
authors.lastname: Siddiqui
authors.forename: F M
authors.initials: FM
authors.lastname: Mullinix
mesh_terms: D000328:Adult; D000368:Aged; D002763:Cholecystectomy; D002764:Cholecystitis / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000473:pathology; D005260:Female; D005704:Gallbladder / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D007098:Imino Acids; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D019780:Technetium Tc 99m Lidofenin
chemical_list: D007098:Imino Acids; D015609:Organotechnetium Compounds; D019780:Technetium Tc 99m Lidofenin