Ifosfamide in pediatric oncology.
Ifosfamide is an effective drug for the treatment of solid tumors in children and most blastomas and sarcomas react favorably. It is administered in combination chemotherapy protocols. In young children, nephrotoxicity is a serious side effect. In older boys, gonadal damage is the major late side effect.
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University of Amsterdam Werkgroep Kindertumoren, Emma Kinderziekenhuis, Academic Medical Centre, The Netherlands.
de Kraker
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D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D002985:Clinical Protocols; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009369:Neoplasms / Q000188:drug therapy*
D007069:Ifosfamide