title: Relation between middle cerebral artery blood flow velocity and stump pressure during carotid endarterectomy.
abstract: OBJECTIVE
  Many patient monitoring techniques have been used for detecting cerebral hypoperfusion during carotid endarterectomy. We compared middle cerebral artery blood flow velocities with carotid artery stump pressures to evaluate the indications for common carotid artery cross-clamp shunting and the probable hemodynamic causes of cerebrovascular complications.
  
  
  METHODS
  Blood flow velocities were monitored with transcranial Doppler ultrasound and carotid stump pressures were measured at the time of common carotid artery cross-clamping during 97 carotid endarterectomy procedures. Stump pressures measured with the gauge zero reference at the common carotid artery level were correlated with the percentage change of velocities.
  
  
  RESULTS
  Middle cerebral artery blood flow velocities usually decreased upon common carotid artery cross-clamping, depending on collateral availability and the autoregulation response. The best fit of the data was to an exponential function concave to the pressure axis, with velocity as a percentage of the pre-cross-clamp value reaching zero at 15 mm Hg stump pressure (r = 0.85 and p less than 0.001).
  
  
  CONCLUSIONS
  There is a less critical margin of error with percentage middle cerebral artery blood flow velocity decreases than with stump pressure measurements. This relation establishes changes in middle cerebral artery blood flow velocities as a reliable parameter for judging the effects of carotid cross-clamping on cerebral blood flow and providing an excellent indicator as to the necessity for shunting.
authors.affiliation: Center for Stroke Research, Seattle, Wash.
authors.forename: M P
authors.initials: MP
authors.lastname: Spencer
authors.forename: G I
authors.initials: GI
authors.lastname: Thomas
authors.forename: M A
authors.initials: MA
authors.lastname: Moehring
mesh_terms: D001783:Blood Flow Velocity; D001794:Blood Pressure; D002339:Carotid Arteries / Q000502:physiology*; D002536:Cerebral Arteries / Q000502:physiology*; D002561:Cerebrovascular Disorders / Q000209:etiology; D016894:Endarterectomy, Carotid / Q000009:adverse effects; D006801:Humans