Shoshin beriberi in an infant of a thiamine-deficient mother.
The classical form of thiamine deficiency in children is comprised of peripheral neuropathy, encephalopathy and high-output cardiac failure, predominantly right-sided. "Shoshin beriberi" cardiac failure has a different presentation, with vasoconstriction, hypotension and severe metabolic acidosis. A three-month breast-fed infant developed these features (biochemical tests confirmed the diagnosis). His mother, although non-symptomatic, had biochemical evidence of thiamine deficiency.
Debuse
P J
PJ
Paediatric Intensive Care Unit, Royal Children's Hospital, Brisbane, Australia.
D000328:Adult; D001602:Beriberi / Q000151:congenital* / Q000503:physiopathology; D001942:Breast Feeding; D002675:Child, Preschool; D005260:Female; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications; D013832:Thiamine Deficiency / Q000150:complications*