Fetal development of mice following intrauterine exposure to a static magnetic field of 6.3 T.
The study was undertaken to investigate possible teratogenic effects of a high magnetic field on fetal development in mice. Eighty-four pregnant CD-1 mice (ICR) were exposed to a static magnetic field of 6.3 T for 1 hr a day from day 7 through day 14 of gestation, a period corresponding to major organogenesis. Fifty mice served as controls. Dams were sacrificed on day 18 of gestation. Fetuses were examined for both external and skeletal abnormalities. No significant differences between exposed and control groups were observed regarding litter size, fetal weight, intrauterine mortality rate, or external and skeletal anomalies. The effects of static magnetic field of 6.3 T on the parameters studied appear negligible.
Murakami
J
J
Department of Radiology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Torii
Y
Y
Masuda
K
K
D000818:Animals; D001842:Bone and Bones / Q000002:abnormalities; D000013:Congenital Abnormalities / Q000209:etiology*; D005313:Fetal Death / Q000209:etiology; D008280:Magnetics / Q000009:adverse effects*; D051379:Mice; D008813:Mice, Inbred ICR