IgG4-anti-IgE antibodies in Chinese allergic children.
IgG4-anti-IgE antibodies have been identified in normal nonatopic subjects, as well as in allergic patients. Their potential role remains controversial. We studied 44 Chinese children with allergic symptoms, and measured their IgG4-anti-IgE serum levels using a modified IgG4 FAST assay. The levels of IgG4-anti-IgE antibodies did not correlate with clinical status. The usefulness and relevance of these measurements remain questionable in allergic patients.
Chang
C C
CC
Department of Internal Medicine, University of California Davis School of Medicine 95616.
Halpern
G M
GM
Tam
A Y
AY
Lau
Y L
YL
Yeung
C Y
CY
D000293:Adolescent; D000888:Antibodies, Anti-Idiotypic / Q000097:blood* / Q000276:immunology; D001323:Autoantibodies / Q000097:blood / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D002681:China; D005260:Female; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology*; D007118:Immunoassay; D007073:Immunoglobulin E / Q000276:immunology*; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology*; D007223:Infant; D007428:Intradermal Tests; D008297:Male
D000888:Antibodies, Anti-Idiotypic; D001323:Autoantibodies; D007074:Immunoglobulin G; D007073:Immunoglobulin E