Recurrence of neisserial meningococcemia due to deficiency of terminal complement component.
Recurrent infections with Neisseria meningitidis are attributed to deficiencies of terminal complement components. The serotype most commonly responsible for recurrent N meningitidis infections is serotype Y. We have reported a case of recurrent meningitis due to N meningitidis in a patient who was found to be deficient in the sixth component of complement. Complement deficiencies should be considered in any patient with recurrent infections caused by N meningitidis.
Morris
J T
JT
Infectious Disease Service, Brooke Army Medical Center, Fort Sam Houston, Tex. 78234-6200.
Kelly
W J
WJ
D000328:Adult; D016470:Bacteremia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D003183:Complement C6 / Q000172:deficiency*; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000150:complications*; D008297:Male; D008589:Meningococcal Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D009345:Neisseria meningitidis; D010400:Penicillin G / Q000627:therapeutic use; D012008:Recurrence
D003183:Complement C6; D010400:Penicillin G