[Treatment of purpuric nephritis in children with Tripterygium wilfordii and radix Salviae miltiorrhizae].
This paper dealt with the data of Tripterygium wilfordii polyoglucoside (1 mg/kg.d) combined with Radix Salvaie multiorrhizae (6-15 g/d) for treating purpuric nephritis (group-A), compared with the control group of using Tripterygium wilfordii polyoglucoside treatment only (group-B). The average time of edema-disappearing and blood pressure-resuming to normal range were 8.72 +/- 3.07 and 7.44 +/- 5.17 days in group-A, which were much better than those in group-B (P < 0.05). The average time of blood urine-disappearing in group-A and group-B were 36.37 +/- 11.50 and 47.73 +/- 14.03 days respectively. The average time on C3 in the urine resumed to normal in groups A and B were 40.33 +/- 4.51 and 50.00 +/- 5.30 days respectively (P < 0.01). The time of microcirculation of nail fold returned to normal after treatment in group-A and group-B were 39.00 +/- 11.03 and 66.00 +/- 9.01 days respectively (P < 0.001). These results indicated that the effect of group-A was much better than that of group-B.
Yu
H L
HL
Children Hospital of Nanjing.
D000293:Adolescent; D002648:Child; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000627:therapeutic use*; D005260:Female; D006027:Glycosides / Q000627:therapeutic use; D006801:Humans; D011695:IgA Vasculitis / Q000150:complications / Q000188:drug therapy*; D008297:Male; D009393:Nephritis / Q000188:drug therapy* / Q000209:etiology; D010936:Plant Extracts; D027561:Salvia miltiorrhiza; D029757:Tripterygium
D004365:Drugs, Chinese Herbal; D006027:Glycosides; D010936:Plant Extracts