title: The developmental relationship between NK cells and T cells.
abstract: NK cells and T cells share many features, suggesting that they have a common origin. Here, Lewis Lanier and colleagues describe recent studies of fetal ontogeny and thymic development that provide support for this hypothesis, and propose an integrated scheme for NK-cell and T-cell development.
authors.affiliation: DNAX Research Institute for Cellular and Molecular Biology, Palo Alto, CA 94304.
authors.forename: L L
authors.initials: LL
authors.lastname: Lanier
authors.forename: H
authors.initials: H
authors.lastname: Spits
authors.forename: J H
authors.initials: JH
authors.lastname: Phillips
mesh_terms: D000818:Animals; D017252:CD3 Complex / Q000276:immunology; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*; D008213:Lymphocyte Activation; D011948:Receptors, Antigen, T-Cell / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D013950:Thymus Gland / Q000196:embryology / Q000276:immunology
chemical_list: D017252:CD3 Complex; D011948:Receptors, Antigen, T-Cell