Occurrence of bacteremia in hematologic patients.
In the present study we reviewed eighty-six episodes of bacteremia occurred in 60 neutropenic patients and thirty-one episodes occurred in 30 non-neutropenic patients. Twenty-four out of 60 neutropenic patients suffered from multiple episodes of bacteremia, while only one out of 30 non-neutropenic patients presented multiple episodes. In neutropenic patients, 29 episodes of bacteremia were polymicrobial, whereas only one non-neutropenic patient had polymicrobial bacteremia. Intravascular catheters were the most common source of bacteremia (23.2%) in neutropenic patients, as compared with infections of the genito-urinary tract (45.1%) among non-neutropenic patients. In both groups, aerobic gram-positive cocci were the microorganisms most frequently isolated (71.6%). Anaerobic microorganisms showed an higher incidence in polymicrobial episodes than in monomicrobial episodes x 2 = 5.39 p = 0.02 OR = 2.97 95% CI (1.2-7.7).
D'Antonio
D
D
Cattedra di Ematologia, Università G. D'Annunzio, Chieti, Italy.
Pizzigallo
E
E
Iacone
A
A
Dell'Isola
M
M
Fioritoni
G
G
Betti
S
S
Piergallini
A
A
Di Gianfilippo
R
R
Olioso
P
P
Torlontano
G
G
D000293:Adolescent; D000328:Adult; D000368:Aged; D016470:Bacteremia / Q000150:complications* / Q000382:microbiology; D016026:Bone Marrow Transplantation; D002404:Catheterization / Q000009:adverse effects; D002939:Ciprofloxacin / Q000627:therapeutic use; D005260:Female; D052776:Female Urogenital Diseases / Q000382:microbiology; D006689:Hodgkin Disease / Q000150:complications; D006801:Humans; D007938:Leukemia / Q000150:complications* / Q000188:drug therapy; D008223:Lymphoma / Q000150:complications* / Q000188:drug therapy; D008228:Lymphoma, Non-Hodgkin / Q000150:complications; D008297:Male; D052801:Male Urogenital Diseases; D008875:Middle Aged; D009503:Neutropenia / Q000150:complications; D016017:Odds Ratio; D015242:Ofloxacin / Q000627:therapeutic use; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000150:complications; D013212:Staphylococcus epidermidis / Q000302:isolation & purification
D002939:Ciprofloxacin; D015242:Ofloxacin