4-Oxospiro[benzopyran-2,4'-piperidines] as class III antiarrhythmic agents. Pharmacological studies on 3,4-dihydro-1'-[2-(benzofurazan-5-yl)- ethyl]-6-methanesulfonamidospiro[(2H)-1-benzopyran-2,4'-piperidin]-4-on e (L-691,121).
Elliott
J M
JM
Department of Medicinal Chemistry, Merck Research Laboratories, West Point, Pennsylvania 19486.
Selnick
H G
HG
Claremon
D A
DA
Baldwin
J J
JJ
Buhrow
S A
SA
Butcher
J W
JW
Habecker
C N
CN
King
S W
SW
Lynch
J J
JJ
Phillips
B T
BT
D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000737:chemistry / Q000494:pharmacology*; D004285:Dogs; D010881:Piperidones / Q000737:chemistry / Q000494:pharmacology*; D013141:Spiro Compounds / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D000889:Anti-Arrhythmia Agents; D010881:Piperidones; D013141:Spiro Compounds; C077569:L 691121