(R)-2-(3-mercapto-2(S)-methyl-1-oxo-propoxy)-3-(methylthio)propanoic acid, the first ultra-short-acting angiotensin converting enzyme inhibitor.
Baxter
A J
AJ
Department of Medicinal Chemistry, Pharmaceutical Division, Research and Development Laboratories, Loughborough, Leicestershire, United Kingdom.
Carr
R D
RD
Eyley
S C
SC
Fraser-Rae
L
L
Hallam
C
C
Harper
S T
ST
Hurved
P A
PA
King
S J
SJ
Meghani
P
P
D000806:Angiotensin-Converting Enzyme Inhibitors / Q000138:chemical synthesis*; D000818:Animals; D002216:Captopril / Q000031:analogs & derivatives*; D006801:Humans; D006868:Hydrolysis; D011422:Propionates / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats; D013329:Structure-Activity Relationship
D000806:Angiotensin-Converting Enzyme Inhibitors; D011422:Propionates; C078160:FPL 66564; D002216:Captopril