title: Loco-regional recurrence and survival after wide local excision, radiotherapy and axillary clearance for early breast cancer.
abstract: After breast conservation for early breast cancer which comprised wide local excision, axillary clearance and radiotherapy to the breast, 145 women have been followed prospectively for a median of 42 months. Local recurrence occurred in 11 (7%) and axillary recurrence in three (2%). Distant recurrence has occurred in 32 and accounted for 80% of all first recurrences. Local treatment failure has occurred in three women and would not have been prevented by mastectomy. Loco-regional recurrence in the absence of preceding or synchronous distant disease was unusual and did not pose a significant clinical problem.
authors.affiliation: University Surgical Unit, Royal South Hants Hospital, Southampton.
authors.forename: R
authors.initials: R
authors.lastname: Carpenter
authors.forename: G T
authors.initials: GT
authors.lastname: Royle
authors.forename: M
authors.initials: M
authors.lastname: Cross
authors.forename: C
authors.initials: C
authors.lastname: Hamilton
authors.forename: R
authors.initials: R
authors.lastname: Buchanan
authors.forename: I
authors.initials: I
authors.lastname: Taylor
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000401:mortality* / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006801:Humans; D007902:Length of Stay; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality*; D011379:Prognosis; D011446:Prospective Studies; D016019:Survival Analysis