Principles and criteria in the development and optimization of topical therapeutic products.
Shah
V P
VP
Center for Drug Evaluation and Research, Food and Drug Administration, Rockville, MD 20875.
Behl
C R
CR
Flynn
G L
GL
Higuchi
W I
WI
Schaefer
H
H
D000287:Administration, Topical; D000818:Animals; D001682:Biological Availability; D002626:Chemistry, Pharmaceutical / Q000379:methods*; D006801:Humans; D008954:Models, Biological; D010599:Pharmacokinetics; D012867:Skin / Q000378:metabolism; D013810:Therapeutic Equivalency