Brain atrophy on computerized axial tomography scans: interaction of age, diabetes and general morbidity.
We evaluated, retrospectively, the occurrence of brain atrophy in all patients (n = 416) with a brain CT scan performed during a 3-month period in 1989 at the Tampere University Central Hospital. Age, diabetes, hypertension, chronic cerebrovascular disorders and an increasing number of medications were associated with brain atrophy in the log-linear models. We suggest that the effect of various systemic medical disorders on the brain requires consideration when evaluating and assessing physiological ageing of the brain.
Pirttilä
T
T
Department of Neurology, Tampere University Central Hospital, Finland.
Järvenpää
R
R
Laippala
P
P
Frey
H
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging / Q000473:pathology*; D001284:Atrophy / Q000000981:diagnostic imaging; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology*; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging / Q000473:pathology*; D003920:Diabetes Mellitus / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D016014:Linear Models; D008875:Middle Aged; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed