[Synthesis of oligodeoxyribonucleotides containing 5-fluoro-2'-deoxyribocytidine].
A synthesis of the phosphoroamidite derivative of 5-fluoro-2'-deoxycytidine which allows one to introduce the modified nucleoside residue into the 5'-position of the oligodeoxyribonucleotide by the standard solid phase phosphoroamidite method, has been carried out. Oligonucleotides with 5-fluoro-2'-deoxycytidine residues in various positions of the DNA strand are obtained by the combination of chemical and enzymatic syntheses.
Kubareva
E A
EA
Romanova
E A
EA
Oretskaia
T S
TS
Gromova
E S
ES
Shabarova
Z A
ZA
D001483:Base Sequence; D002851:Chromatography, High Pressure Liquid; D004247:DNA / Q000737:chemistry; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D008969:Molecular Sequence Data; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis* / Q000302:isolation & purification
D009838:Oligodeoxyribonucleotides; D003841:Deoxycytidine; D004247:DNA; C007746:5-fluoro-2'-deoxycytidine
Sintez oligodezoksiribonukleotidov, soderzhashchikh 5-ftor-2'-dezoksiribotsitidin.