title: Effect of Galphimia glauca methanolic extract on neuropharmacological tests.
abstract: Galphimia glauca Cav. (Malpighiaceae) is used in Mexican traditional medicine for the treatment of nervous excitement. A methanolic extract from its aerial parts (MEGA) was tested in several neuropharmacological animal models including among others: hypothermic activity, barbiturate potentiation, protection against strychnine- and leptazol-induced convulsions. The combined data obtained from all biological models demonstrate the sedative property of this plant product.
authors.affiliation: Traditional Medicine and Drug Development Research Unit, Mexican Institute of Social Security, IMSS.
authors.forename: J
authors.initials: J
authors.lastname: Tortoriello
authors.forename: X
authors.initials: X
authors.lastname: Lozoya
mesh_terms: D000818:Animals; D006993:Hypnotics and Sedatives / Q000494:pharmacology*; D008297:Male; D009420:Nervous System / Q000187:drug effects*; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D051381:Rats; D017208:Rats, Wistar
chemical_list: D006993:Hypnotics and Sedatives; D010936:Plant Extracts