Histopathological study of focal dermal hypoplasia (Goltz syndrome).
We report a case of focal dermal hypoplasia, or Golz syndrome in a 13-year-old girl. The patient presented with a variety of cutaneous defects, including atrophy-like depressions, striations, a verrucous papilloma, and lipomas. Histopathological examination showed deposits of fat cells or adipose tissue in the dermis, which were subepidermal, mid-dermal, perivascular, or involved the whole dermis. These findings indicate that the adipose tissue in the dermis is a result of dermal dysplasia and not hypoplasia.
Ishii
N
N
Department of Dermatology, Yokohama City University School of Medicine, Japan.
Baba
N
N
Kanaizuka
I
I
Nakajima
H
H
Ono
S
S
Amemiya
F
F
D000293:Adolescent; D001706:Biopsy; D005260:Female; D005489:Focal Dermal Hypoplasia / Q000473:pathology*; D006801:Humans; D012867:Skin / Q000473:pathology*