title: Defect reconstruction and cerebrospinal fluid management in neurotologic skull base tumors with intracranial extension.
abstract: Intracranial extension (ICE) is the spread of tumor into the subarachnoid space through dura or along cranial nerve roots. The single-stage removal of the skull base tumor with its ICE has been confounded by cerebrospinal fluid management and defect reconstruction. The purpose of this report is to review a current protocol for managing the cranial base tumor and its ICE as a unit. The ventricular shunting paper of 1987 is retracted. All tumors were managed at a single stage. Defect reconstruction was size dependent. Ninety-eight neurotologic skull base tumors with ICE were managed from 1971 to 1991. The new protocol was initiated in 1987. Results specific to this group are highlighted. For glomus tumors, cerebrospinal fluid leak rates have been dramatically reduced overall from 14.5% to 4%. The leak rates for nonglomus tumors, overall, have improved slightly. Complications are discussed. The development of this surgical approach protocol improves the functional outcome in patients of surgeons who aspire to disease "cure" rather than "control."
authors.affiliation: Otology Group, Nashville, TN 37203.
authors.forename: C G
authors.initials: CG
authors.lastname: Jackson
authors.forename: J L
authors.initials: JL
authors.lastname: Netterville
authors.forename: M E
authors.initials: ME
authors.lastname: Glasscock
authors.forename: C R
authors.initials: CR
authors.lastname: Hampf
authors.forename: V N
authors.initials: VN
authors.lastname: Carrasco
authors.forename: D S
authors.initials: DS
authors.lastname: Haynes
authors.forename: B
authors.initials: B
authors.lastname: Strasnick
authors.forename: J
authors.initials: J
authors.lastname: Fisher
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002558:Cerebrospinal Fluid Otorrhea / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D002559:Cerebrospinal Fluid Rhinorrhea / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D002985:Clinical Protocols / Q000592:standards*; D003399:Craniotomy / Q000009:adverse effects / Q000379:methods* / Q000592:standards; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D012189:Retrospective Studies; D012888:Skull Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D013346:Subarachnoid Space; D013524:Surgical Flaps / Q000379:methods / Q000592:standards; D013701:Temporal Bone; D013714:Tennessee / Q000453:epidemiology