title: The effect of proximal gastric vagotomy plus duodenoplasty on duodenogastric reflux.
abstract: Alkaline reflux gastritis is a clinical syndrome that results from a mucosal injury by duodenal contents. In this study, the amount of duodenogastric reflux was assessed in patients who previously underwent proximal gastric vagotomy (PGV group; n = 11) and PGV plus duodenoplasty (PGV+D group; n = 10) as a treatment for duodenal ulcer. The control group (A) consisted of 11 healthy volunteers without endoscopic abnormalities. A quantitative index of duodenogastric reflux was obtained in each case by determining the percentage of the injected dose of 99mTechnetium-DISIDA that was recovered by continuous aspiration of gastric juice in fasting subjects. In the PGV group, the percentage of administered 99mTechnetium-DISIDA recovered from the stomach (median: 0.69%; range: 0.09%-3.61%) did not differ significantly (P > 0.05) from that of the PGV+D group (median: 0.49%; range: 0.09%-3.91%) and from that of the A group (median: 1.47%; range: 0.22%-3.01%). The results show that proximal gastric vagotomy plus duodenoplasty did not increase duodenogastric reflux.
authors.affiliation: Department of Surgery, Hospital and Medical School of Ribeirão Preto, University of São Paulo, Brazil.
authors.forename: E N
authors.initials: EN
authors.lastname: Morais
authors.forename: J I
authors.initials: JI
authors.lastname: Andrade
authors.forename: C T
authors.initials: CT
authors.lastname: Hsien
authors.forename: J
authors.initials: J
authors.lastname: Barbieri Neto
authors.forename: W V
authors.initials: WV
authors.lastname: Vicente
authors.forename: R
authors.initials: R
authors.lastname: Ceneviva
mesh_terms: D004381:Duodenal Ulcer / Q000150:complications / Q000601:surgery; D004383:Duodenogastric Reflux / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D004386:Duodenum / Q000601:surgery*; D005260:Female; D006801:Humans; D007098:Imino Acids; D008297:Male; D015609:Organotechnetium Compounds; D012016:Reference Values; D012086:Reoperation; D019785:Technetium Tc 99m Disofenin; D014629:Vagotomy, Proximal Gastric
chemical_list: D007098:Imino Acids; D015609:Organotechnetium Compounds; D019785:Technetium Tc 99m Disofenin