title: Malignant melanoma in a Hispanic male with nevus of Ota.
abstract: Nevus of Ota is uncommon in the non-Oriental population. We report a case of malignant melanoma with metastasis to the genitourinary tract in a Hispanic male with nevus of Ota. Thirty-six prior cases of nevus of Ota with malignant melanoma reported in the English language are reviewed. Sixty-eight percent were women; 76% were Caucasians. Metastatic disease was reported in 16%. Three patients had liver metastases. Our case was the first involving the genitourinary tract. All but one patient with metastatic disease died within 1 month of presentation. Despite the increased frequency of nevus of Ota in the Japanese, only 4 cases of malignant melanoma have been reported. Nevus of Ota would appear to be a risk factor for developing malignant melanoma in the Caucasian population.
authors.affiliation: University of Texas Health Science Center, San Antonio.
authors.forename: D
authors.initials: D
authors.lastname: Shaffer
authors.forename: K
authors.initials: K
authors.lastname: Walker
authors.forename: G R
authors.initials: GR
authors.lastname: Weiss
mesh_terms: D001932:Brain Neoplasms / Q000473:pathology; D005153:Facial Neoplasms / Q000208:ethnology* / Q000473:pathology; D006630:Hispanic or Latino; D006801:Humans; D008297:Male; D008545:Melanoma / Q000208:ethnology / Q000473:pathology* / Q000556:secondary; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000208:ethnology / Q000473:pathology*; D009507:Nevus of Ota / Q000208:ethnology* / Q000473:pathology; D012307:Risk Factors; D013702:Temporal Lobe / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000556:secondary