title: [Changes in the concentration of beta-endorphin in the cerebrospinal fluid due to morphine analgesia in incurable oncologic patients].
abstract: Thirty cancer patients, clinical group IV, have been examined. It has been established that a persistent pain syndrome leads to lowering in beta-endorphin liquor level. Morphine analgesia is followed by beta-endorphin level elevation which directly depends on pain intensity and analgesia efficacy. Determination of changes in beta-endorphin liquor level may serve as a criterion of analgesia efficacy.
authors.forename: M E
authors.initials: ME
authors.lastname: Isakova
authors.forename: Z V
authors.initials: ZV
authors.lastname: Pavlova
authors.forename: L S
authors.initials: LS
authors.lastname: Bassalyk
authors.forename: N E
authors.initials: NE
authors.lastname: Kushlinskiĭ
mesh_terms: D015360:Analgesia, Epidural; D005260:Female; D006801:Humans; D008297:Male; D009020:Morphine; D009369:Neoplasms / Q000503:physiopathology*; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D001615:beta-Endorphin / Q000134:cerebrospinal fluid*
chemical_list: D001615:beta-Endorphin; D009020:Morphine
vernacular_title: Izmeneniia kontsentratsiĭ beta-éndorfina v likvore pod vliianiem spinal'noĭ analgezii morfinom u inkurabel'nykh onkologicheskikh bol'nykh.