title: [Effect of indirect endolymphatic antibiotic therapy on clinical and immunological indicators in patients with erysipelas of the lower extremities].
abstract: Two groups of patients with erysipelas of the lower extremities underwent indirect endolymphatic therapy with bicillin-3 (58 patients) and routine penicillin therapy (79 patients). Comparative clinicoimmunological examinations in the two groups revealed that lymphotropic administration of the antibiotic had a more favourable effect on the disease process, as evidenced by more rapid reverse time courses of erysipelas clinical signs, less frequent incidence of early relapses and normalization of the majority of immunological parameters by the end of the treatment. For estimation of the anti-recurrence efficacy of the antibiotic therapy in the patients with erysipelas, it was recommended to use a specific scale based on the principles of the Wald successive alternative analysis.
authors.forename: L D
authors.initials: LD
authors.lastname: Levina
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Ambalov
authors.forename: A I
authors.initials: AI
authors.lastname: Poliak
authors.forename: N S
authors.initials: NS
authors.lastname: Aĭtkuluev
authors.forename: A P
authors.initials: AP
authors.lastname: Kovalenko
authors.forename: A V
authors.initials: AV
authors.lastname: Usatkin
mesh_terms: D000328:Adult; D000368:Aged; D000936:Antigen-Antibody Complex / Q000032:analysis*; D017252:CD3 Complex / Q000032:analysis*; D016516:CD4-CD8 Ratio / Q000187:drug effects*; D004359:Drug Therapy, Combination / Q000008:administration & dosage; D004886:Erysipelas / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D007272:Injections, Intralymphatic; D007868:Leg Dermatoses / Q000188:drug therapy* / Q000276:immunology; D008875:Middle Aged; D010400:Penicillin G / Q000008:administration & dosage*; D010401:Penicillin G Benzathine / Q000008:administration & dosage*; D010402:Penicillin G Procaine / Q000008:administration & dosage*
chemical_list: D000936:Antigen-Antibody Complex; D017252:CD3 Complex; C024657:benzathine benzylpenicillin, procaine benzylpenicillin, drug combination; D010402:Penicillin G Procaine; D010400:Penicillin G; D010401:Penicillin G Benzathine
vernacular_title: Vliianie nepriamoĭ éndolimfaticheskoĭ antibiotikoterapii na klinicheskie i immunologicheskie pokazateli u bol'nykh rozheĭ nizhnikh konechnosteĭ.