Analogs of CCK incorporating conformationally constrained replacements for Asp32.
Tilley
J W
JW
Roche Research Center, Nutley, New Jersey 07110.
Danho
W
W
Madison
V
V
Fry
D
D
Swistok
J
J
Makofske
R
R
Michalewsky
J
J
Schwartz
A
A
Weatherford
S
S
Triscari
J
J
D000595:Amino Acid Sequence; D000818:Animals; D001067:Appetite Depressants / Q000138:chemical synthesis* / Q000494:pharmacology; D001224:Aspartic Acid; D002417:Cattle; D002766:Cholecystokinin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D066298:In Vitro Techniques; D008297:Male; D008958:Models, Molecular; D008969:Molecular Sequence Data; D011487:Protein Conformation; D051381:Rats; D017207:Rats, Sprague-Dawley; D011949:Receptors, Cholecystokinin / Q000378:metabolism; D013329:Structure-Activity Relationship
D001067:Appetite Depressants; D011949:Receptors, Cholecystokinin; D001224:Aspartic Acid; D002766:Cholecystokinin