[Radiation reactions and the possibilities for their modification in rats exposed in the area of the Chernobyl Atomic Electric Power Station].
A study was made of some embryological, hematological, cytogenetic and biochemical characteristics in Wistar rats exposed within the Chernobyl NPP zone over a period of 30 days (the average radiation background level, 75, and at the soil surface, 115 mR/h; a cumulative dose, 57 rad/30 days, and for pregnant rats, 36 rad/20 days). The quantity of chromosome aberrations in bone marrow metaphases and the embryonal death rate were invariable; some cases of teratogenesis were, however, observed. The total number of karyocytes in the brain and the leukocyte content in the peripheral blood sometimes decreased. The changes in certain characteristics (such as the content of endogenous amines and thiols in the liver and spleen) of the endogenous radioresistance background (ERB) and the normalization of the ERB by the radioprotective agent MIGI-K were found.
Izmozherova
E L
EL
Izmozherov
N A
NA
Bachinskaia
T L
TL
Impolitova
S M
SM
Aristova
V A
VA
Goncharenko
E N
EN
Gorskaia
T G
TG
Graevskaia
E E
EE
Deev
L I
LI
Kudriashov
Iu B
IuB
D000059:Accidents; D000396:Air Pollutants, Radioactive / Q000009:adverse effects*; D000818:Animals; D004307:Dose-Response Relationship, Radiation; D004353:Drug Evaluation, Preclinical; D005260:Female; D008297:Male; D009688:Nuclear Reactors; D011210:Power Plants; D011833:Radiation Injuries, Experimental / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D011837:Radiation-Protective Agents / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar; D014455:Ukraine
D000396:Air Pollutants, Radioactive; D011837:Radiation-Protective Agents
Issledovanie nekotorykh luchevykh reaktsiĭ i vozmozhnosti ikh modifikatsii u krys, éksponirovannykh v zone Chernobyl'skoĭ AES.