title: Sucralfate and sodium sucrose sulphate in the treatment of superficial corneal disease in keratoconjunctivitis sicca.
abstract: We have studied the effect of the aluminum complex of sucrose sulphate (Sucralfate suspension) and the sodium salt of sucrose sulphate (sodium sucrose sulphate solution) on patients with keratoconjunctivitis sicca. Eyes treated with either of these two drugs showed a decrease in painfulness and blurring of vision. On examination the surface area of the corneal lesions, stained with fluorescein, diminished during treatment. As for the difference in effect between the two eyedrops, the solution was better tolerated.
authors.affiliation: Department of Ophthalmology, Utrecht State University Hospital, The Netherlands.
authors.forename: O P
authors.initials: OP
authors.lastname: van Bijsterveld
authors.forename: O L
authors.initials: OL
authors.lastname: van Hemel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003315:Cornea / Q000187:drug effects / Q000473:pathology; D004361:Drug Tolerance; D004848:Epithelium / Q000187:drug effects / Q000473:pathology; D005260:Female; D015590:Fluorophotometry; D006801:Humans; D007638:Keratoconjunctivitis Sicca / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions / Q000627:therapeutic use; D013392:Sucralfate / Q000627:therapeutic use*; D013395:Sucrose / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D009883:Ophthalmic Solutions; C062375:sucrose sulfate; D013392:Sucralfate; D013395:Sucrose