Brain injury in the premature infant--current concepts of pathogenesis and prevention.
Brain injury in the premature infant and, particularly, the prevention of that injury is an enormous problem. With modern neonatal intensive care, approximately 85% of very low birth weight infants survive, and of these survivals, approximately 5-15% exhibit major spastic motor deficit, grouped under the rubric, 'cerebral palsy', and an additional 25-50% exhibit less prominent developmental disabilities, particularly school failure.
Volpe
J J
JJ
Department of Neurology, Children's Hospital, Boston, Mass. 02115.
D001930:Brain Injuries / Q000209:etiology* / Q000473:pathology / Q000517:prevention & control; D002543:Cerebral Hemorrhage / Q000209:etiology; D002544:Cerebral Infarction / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007969:Leukomalacia, Periventricular / Q000209:etiology; D009422:Nervous System Diseases / Q000209:etiology / Q000473:pathology