Protein prenylation: key to ras function and cancer intervention?
Khosravi-Far
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La Jolla Cancer Research Foundation, La Jolla, California 92037.
Cox
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Kato
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D019883:Alkyl and Aryl Transferases; D000595:Amino Acid Sequence; D005656:Fungal Proteins / Q000378:metabolism; D019204:GTP-Binding Proteins / Q000378:metabolism; D006801:Humans; D008148:Lovastatin / Q000031:analogs & derivatives / Q000494:pharmacology / Q000627:therapeutic use; D008798:Mevalonic Acid / Q000378:metabolism; D008969:Molecular Sequence Data; D009363:Neoplasm Proteins / Q000378:metabolism; D009369:Neoplasms / Q000188:drug therapy; D011106:Polyisoprenyl Phosphates / Q000378:metabolism; D011499:Protein Processing, Post-Translational / Q000187:drug effects; D016283:Proto-Oncogene Proteins p21(ras) / Q000378:metabolism* / Q000502:physiology; D012441:Saccharomyces cerevisiae / Q000201:enzymology / Q000235:genetics; D014166:Transferases / Q000378:metabolism; D018631:ras Proteins
D005656:Fungal Proteins; D009363:Neoplasm Proteins; D011106:Polyisoprenyl Phosphates; C012258:mevastatin; D008148:Lovastatin; D014166:Transferases; D019883:Alkyl and Aryl Transferases; C083291:geranylgeranyltransferase type-I; C064911:p21(ras) farnesyl-protein transferase; D019204:GTP-Binding Proteins; C501009:HRAS protein, human; D016283:Proto-Oncogene Proteins p21(ras); D018631:ras Proteins; D008798:Mevalonic Acid