Preservation of hearing and facial nerve function in resection of acoustic neuroma.
The surgical results in 78 recent cases of total removal of unilateral acoustic neuroma in which an attempt was made to preserve cochlear function have been added to the authors' previous series of 66 cases to evaluate the factors influencing the ability to preserve useful hearing. Useful hearing was defined by speech reception threshold no poorer than 70 dB and a discrimination score of at least 15%. Analysis using a logistic regression model showed that certain preoperative clinical parameters such as tumor size, speech discrimination score, and gender were significantly correlated with hearing outcome. Favorable outcome was significantly correlated with smaller tumor size, higher preoperative speech discrimination score, and male sex. From this data, an explicit formula was devised for predicting hearing outcome for an individual patient. In four cases with useful hearing preserved, there was improvement of greater than 15 percentage points in speech discrimination scores. While preoperative auditory brainstem responses were not predictive of hearing preservation, monitoring of intraoperative auditory evoked potentials was predictive of hearing outcome in selected cases. Specifically, when wave V was unchanged at the end of the operation, even if it may have been transiently lost during surgery, useful hearing was invariably preserved.
Nadol
J B
JB
Department of Otology and Laryngology, Harvard Medical School, Boston, MA.
Chiong
C M
CM
Ojemann
R G
RG
McKenna
M J
MJ
Martuza
R L
RL
Montgomery
W W
WW
Levine
R A
RA
Ronner
S F
SF
Glynn
R J
RJ
D001300:Audiometry, Evoked Response; D016057:Evoked Potentials, Auditory, Brain Stem; D005158:Facial Paralysis / Q000453:epidemiology / Q000517:prevention & control*; D005260:Female; D034381:Hearing Loss / Q000453:epidemiology / Q000517:prevention & control*; D006801:Humans; D008297:Male; D016343:Monitoring, Intraoperative / Q000379:methods*; D009464:Neuroma, Acoustic / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology / Q000517:prevention & control*; D011237:Predictive Value of Tests; D012044:Regression Analysis; D013063:Speech Discrimination Tests; D013069:Speech Reception Threshold Test