title: Prenatal presentation of congenital chloride diarrhea: clinical report and review of the literature.
abstract: A case of congenital chloride diarrhea was diagnosed after delivery in a patient whose antenatal course was notable for massively dilated small and large bowel and persistent, severe hydramnios refractory to therapy. The pathophysiologic mechanism is a dysfunctional chloride-bicarbonate exchange in the brush border of the ileum. Antenatal presentation, prenatal diagnosis, and a review of the current literature are discussed.
authors.affiliation: Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia 19104.
authors.forename: N C
authors.initials: NC
authors.lastname: Rose
authors.forename: P
authors.initials: P
authors.lastname: Kaplan
authors.forename: S
authors.initials: S
authors.lastname: Scott
authors.forename: A
authors.initials: A
authors.lastname: Kousoulis
authors.forename: R
authors.initials: R
authors.lastname: Librizzi
mesh_terms: D000328:Adult; D000649:Amniocentesis; D002712:Chlorides / Q000502:physiology; D003968:Diarrhea, Infantile / Q000151:congenital* / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007415:Intestinal Obstruction / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D006831:Polyhydramnios / Q000150:complications* / Q000628:therapy; D011247:Pregnancy; D016216:Ultrasonography, Prenatal
chemical_list: D002712:Chlorides