title: Assignment of a novel protein tyrosine phosphatase gene (Hcph) to mouse chromosome 6.
abstract: Hematopoietic cell phosphatase (Hcph) was identified by amplification of conserved protein tyrosine phosphatase sequences from a myeloid cell line and is predominantly expressed in hematopoietic cells. Hcph is unique in containing two, tandemly repeated, src-homology 2 domains in the amino terminal region of the phosphatase. Using a genomic probe in interspecific backcross analysis, the murine Hcph gene maps to mouse Chromosome 6 and is tightly linked to the Tnfr-2 and Ly-4 genes.
authors.affiliation: Department of Biochemistry, St. Jude Children's Research Hospital, Memphis, Tennessee 38105.
authors.forename: T
authors.initials: T
authors.lastname: Yi
authors.forename: D J
authors.initials: DJ
authors.lastname: Gilbert
authors.forename: N A
authors.initials: NA
authors.lastname: Jenkins
authors.forename: N G
authors.initials: NG
authors.lastname: Copeland
authors.forename: J N
authors.initials: JN
authors.lastname: Ihle
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D002881:Chromosomes, Human, Pair 12; D003433:Crosses, Genetic; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D017027:Protein Tyrosine Phosphatases / Q000235:genetics*
chemical_list: D017027:Protein Tyrosine Phosphatases