[The effect of iodine-131 on the binding characteristics of sex and thyroid hormones by blood plasma proteins in children with a functional thyroid disorder as a result of the accident at the Chernobyl Atomic Electric Power Station].
In studying characteristics of specific interaction of estradiol-, testosterone- and thyroid-binding blood globulins with the corresponding ligands in children from Gomel Province with endemic swelling of the thyroid gland (degrees I and II) affected by iodine-131 revealed were a reduced cooperativity in estradiol and T-3 binding and a halved affinity to androgens and thyroids as compared to healthy controls. In addition, there was a drastic decline in the binding capacity of estradiol- and testosterone-binding globulins in the blood plasma. The endemic thyroid gland swelling is supposed to be due to sexual malfunction in teenagers.
Konoplia
E F
EF
Fil'chenkov
G N
GN
Popov
E G
EG
Leonova
L L
LL
Lavnichuk
O N
ON
D000059:Accidents; D000293:Adolescent; D000396:Air Pollutants, Radioactive / Q000009:adverse effects*; D002648:Child; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood / Q000528:radiation effects*; D006801:Humans; D007457:Iodine Radioisotopes / Q000009:adverse effects*; D008297:Male; D009688:Nuclear Reactors; D011210:Power Plants; D011485:Protein Binding / Q000528:radiation effects; D011832:Radiation Injuries / Q000097:blood* / Q000209:etiology; D002094:Republic of Belarus; D013959:Thyroid Diseases / Q000097:blood* / Q000209:etiology; D013963:Thyroid Hormones / Q000097:blood / Q000528:radiation effects*; D014455:Ukraine
D000396:Air Pollutants, Radioactive; D012739:Gonadal Steroid Hormones; D007457:Iodine Radioisotopes; D013963:Thyroid Hormones
Vliianie ĭoda-131 na kharakteristiki sviazyvaniia polovykh i tireoidnykh gormonov belkami plazmy krovi u deteĭ s funktsional'nym narusheniem shchitovidnoĭ zhelezy v rezul'tate avarii na ChAES.