title: Emergent applications of cardiopulmonary support: a multiinstitutional experience.
abstract: The use of emergent portable bypass systems is increasing. Because of limited patient use in any one institution, a combined experience can better determine the applicability of these systems. A total of 187 patients from 17 centers were analyzed. Causes leading to bypass initiation were cardiac arrest (125 patients), cardiogenic shock (44), profound hypothermia (7), pulmonary insufficiency (9), and miscellaneous (2). Weaning from bypass was successful in 30.5% (57 patients). Sixty-four patients (34.2%) were transferred to standard bypass or other modes of circulatory assist. Of the total population, 40 patients (21.4%) were alive greater than 30 days. There were no survivors of unwitnessed arrests. Major diagnostic or therapeutic interventions were carried out on bypass in 74.9% of all patients. In survivors, 77.1% (37/48) had major therapeutic interventions as compared with 50.0% (67/135) of nonsurvivors. Emergency portable bypass systems can successfully resuscitate and support cardiac hemodynamics, although the underlying causes necessitating bypass remain difficult to correct. When corrective intervention can be performed, there is an increased chance of survival. Unwitnessed arrest, prolonged cardiopulmonary resuscitation, and lack of treatment options are relative contraindications. Appropriate patient selection and early application of these systems should lead to improved survival.
authors.affiliation: Emanuel Hospital and Health Center, Portland, Oregon.
authors.forename: J G
authors.initials: JG
authors.lastname: Hill
authors.forename: P S
authors.initials: PS
authors.lastname: Bruhn
authors.forename: S E
authors.initials: SE
authors.lastname: Cohen
authors.forename: M W
authors.initials: MW
authors.lastname: Gallagher
authors.forename: F
authors.initials: F
authors.lastname: Manart
authors.forename: C A
authors.initials: CA
authors.lastname: Moore
authors.forename: P E
authors.initials: PE
authors.lastname: Seifert
authors.forename: P
authors.initials: P
authors.lastname: Askari
authors.forename: C
authors.initials: C
authors.lastname: Banchieri
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002315:Cardiopulmonary Bypass / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D000075202:Contraindications; D004630:Emergencies; D005260:Female; D006323:Heart Arrest / Q000401:mortality / Q000601:surgery*; D006801:Humans; D007035:Hypothermia / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012042:Registries; D012131:Respiratory Insufficiency / Q000401:mortality / Q000601:surgery*; D015996:Survival Rate