title: Preservation of energy metabolites by carnitine in the mouse brain under ischemia.
abstract: Ischemia (decapitation) caused marked changes of energy metabolites in the mouse brain. However, the changes were clearly less severe, when the mouse was pre-treated with L-carnitine. This suggests that L-carnitine may protect the brain from the ischemic attack. Since D-carnitine showed a similar effect, the effects may be due to mechanism(s) other than the 'classical' function of carnitine.
authors.affiliation: Department of Environmental Toxicology, University of Occupational and Environmental Health, Kitakyushu, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Matsuoka
authors.forename: H
authors.initials: H
authors.lastname: Igisu
mesh_terms: D000818:Animals; D002545:Brain Ischemia / Q000378:metabolism / Q000517:prevention & control*; D002331:Carnitine / Q000494:pharmacology*; D004734:Energy Metabolism / Q000187:drug effects*; D051379:Mice; D013237:Stereoisomerism
chemical_list: D002331:Carnitine