title: Endodontic infection and calcium hydroxide-treatment. Effects on periodontal healing in mature and immature replanted monkey teeth.
abstract: Large experimental defects with marginal communication, and small isolated experimental defects were created on the root surfaces of extracted monkey lateral incisors with either open or closed apices. The pulp tissue was either infected or removed, and calcium hydroxide placed in the root canal. The teeth were then replanted and the healing pattern evaluated histomorphometrically after 20 weeks. From the results, it was concluded that (1) an intrapulpal infection promotes marginal epithelial down-growth on a denuded dentin surface irrespective of tooth developmental stage, and that (2) the periodontal healing potential after calcium hydroxide-treatment appears to be higher in teeth with open apices compared with teeth with closed apices, where ankylosis was promoted as opposed to teeth with open apices where significantly more reparative cementum was found.
authors.affiliation: Department of Periodontology, Public Dental Service at Skanstull, Stockholm, Sweden.
authors.forename: L
authors.initials: L
authors.lastname: Blomlöf
authors.forename: A
authors.initials: A
authors.lastname: Lengheden
authors.forename: S
authors.initials: S
authors.lastname: Lindskog
mesh_terms: D000818:Animals; D000844:Ankylosis / Q000473:pathology; D001424:Bacterial Infections / Q000503:physiopathology / Q000628:therapy*; D002126:Calcium Hydroxide / Q000627:therapeutic use; D003238:Connective Tissue / Q000473:pathology; D003739:Dental Cementum / Q000473:pathology; D003788:Dental Pulp Diseases / Q000382:microbiology* / Q000503:physiopathology / Q000628:therapy*; D004848:Epithelium / Q000473:pathology; D008252:Macaca fascicularis; D009805:Odontogenesis; D010510:Periodontal Diseases / Q000473:pathology / Q000503:physiopathology*; D010513:Periodontal Ligament / Q000503:physiopathology; D010514:Periodontal Pocket / Q000473:pathology; D012390:Root Canal Therapy; D012391:Root Resorption / Q000473:pathology; D014076:Tooth Diseases / Q000473:pathology; D014090:Tooth Replantation; D014092:Tooth Root / Q000503:physiopathology; D014945:Wound Healing
chemical_list: D002126:Calcium Hydroxide