[The role of autoimmune reactions in the development of disseminated sclerosis].
The immune status was investigated in 97 patients with multiple sclerosis. Patients of this group showed marked changes at the cellular lever of the immune system. T-lymphocytopenia was accompanied by a dysbalance of the main correlative cells according to a relatively hyposuppressor variant of immune deficit with formation of circulating immune complexes and thermodependent lymphocytotoxic autoantibodies.
Dziuba
A N
AN
Frolov
V M
VM
Gaĭdash
I S
IS
D000328:Adult; D000936:Antigen-Antibody Complex / Q000097:blood; D000961:Antilymphocyte Serum / Q000097:blood; D001323:Autoantibodies / Q000097:blood; D001327:Autoimmune Diseases / Q000209:etiology* / Q000276:immunology; D015551:Autoimmunity; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000209:etiology* / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
D000936:Antigen-Antibody Complex; D000961:Antilymphocyte Serum; D001323:Autoantibodies
Rol' nekotorykh autoimmunnykh reaktsiĭ v razvitii rasseiannogo skleroza.