Analysis and pharmacokinetics of a new prodrug N-l-leucyldoxorubicin and its metabolites in plasma using HPLC with fluorescence detection.
de Jong
J
J
Department of Oncology, Free University Hospital, Amsterdam, The Netherlands.
Vermorken
J B
JB
van der Vijgh
W J
WJ
D002851:Chromatography, High Pressure Liquid; D004317:Doxorubicin / Q000031:analogs & derivatives* / Q000097:blood / Q000378:metabolism / Q000493:pharmacokinetics; D006801:Humans; D011355:Prodrugs / Q000378:metabolism / Q000493:pharmacokinetics*; D013050:Spectrometry, Fluorescence
D011355:Prodrugs; C073409:N-leucyldoxorubicin; D004317:Doxorubicin