Severe exacerbation of chronic active hepatitis B during interferon alpha therapy.
The case of a 52-year-old male with chronic active type B hepatitis in whom severe exacerbation of liver disease was associated with interferon alpha treatment is described. It seems that patients with very active forms of chronic hepatitis B may experience severe and symptomatic exacerbation of liver disease during interferon treatment.
Laskus
T
T
Department of Immunopathology, Institute of Infectious and Parasitic Diseases, Warsaw, Poland.
Radkowski
M
M
Slusarczyk
J
J
Cianciara
J
J
D006509:Hepatitis B / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006521:Hepatitis, Chronic / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D016898:Interferon-alpha / Q000009:adverse effects* / Q000627:therapeutic use; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged
D016898:Interferon-alpha