Hyalohyphomycosis caused by Paecilomyces variotii: a case report, animal pathogenicity and 'in vitro' sensitivity.
A case of cutaneous infection in a 25-year-old male caused by Paecilomyces variotii is described. Animal pathogenicity studies with normal and cortisone-treated mice revealed the predeliction of P. variotii for skin and liver in both normal and cortisone-treated mice and for lungs and heart only in immunosuppressed mice. 5-fluorocytosine gave the best MIC value for P. variotii in vitro. This report documents for the first time that P. variotii causes cutaneous infection.
Naidu
J
J
Department of Biological Sciences, Rani Durgavati University, Jabalpur, India.
Singh
S M
SM
D000328:Adult; D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology*; D003348:Cortisone / Q000494:pharmacology; D003881:Dermatomycoses / Q000382:microbiology*; D005437:Flucytosine / Q000494:pharmacology; D006801:Humans; D016867:Immunocompromised Host; D008099:Liver / Q000382:microbiology; D008168:Lung / Q000382:microbiology; D008297:Male; D051379:Mice; D008826:Microbial Sensitivity Tests; D009181:Mycoses / Q000382:microbiology; D010143:Paecilomyces / Q000187:drug effects / Q000302:isolation & purification* / Q000472:pathogenicity / Q000502:physiology
D000935:Antifungal Agents; D005437:Flucytosine; D003348:Cortisone