title: Amyloidoma of the CNS. I. Clinical and pathologic study.
abstract: We report a 32-year-old man with a 4-year history of headaches, seizures, and dementia secondary to multifocal amyloidomas in the white matter. Immunohistochemical and electron microscopic analyses suggest that the amyloidomas resulted from processing of plasma-cell-derived amyloidogenic protein by microglial cells.
authors.affiliation: Division of Neuropathology, Case Western Reserve University, Cleveland, OH 44106.
authors.forename: M
authors.initials: M
authors.lastname: Cohen
authors.forename: D
authors.initials: D
authors.lastname: Lanska
authors.forename: U
authors.initials: U
authors.lastname: Roessmann
authors.forename: B
authors.initials: B
authors.lastname: Karaman
authors.forename: E
authors.initials: E
authors.lastname: Ganz
authors.forename: P
authors.initials: P
authors.lastname: Whitehouse
authors.forename: P
authors.initials: P
authors.lastname: Gambetti
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D001519:Behavior; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008854:Microscopy, Electron; D009420:Nervous System / Q000503:physiopathology