[Effects of different regimens of hyperbaric oxygenation on transcriptional activity and morphology of frontal cortex neurons in occlusion of the common carotid artery in rats].
The effect of different regimens of hyperbaric oxygenation (HBO) on cortical pyramids morphology and transcription were studied under occlusion of common arteria carotis. The effect of early (3 hours after occlusion) and late (14 hours after occlusion) use of 1.2 and 2.0 ata of HBO was estimated. The rats were killed 15 minutes or 24 hours after HBO session. The effect of early use of HBO was normalizing, stabilizing and independent on the dose. Protecting effect of the late HBO on morphology and transcription activity of nuclear chromatin of pyramids was higher in the 1.2 ata regimen. In case of late HBO both pressures produced depressing effect on the nucleoplasmic chromatin, transcription.
Grigor'eva
A V
AV
Kazantseva
N V
NV
Bul'chuk
O V
OV
D000818:Animals; D002340:Carotid Artery Diseases / Q000473:pathology / Q000628:therapy*; D017536:Carotid Artery, Common; D002843:Chromatin / Q000648:ultrastructure; D005625:Frontal Lobe / Q000473:pathology*; D006931:Hyperbaric Oxygenation; D008297:Male; D009474:Neurons / Q000473:pathology*; D011712:Pyramidal Tracts / Q000648:ultrastructure; D051381:Rats; D013997:Time Factors; D014158:Transcription, Genetic
D002843:Chromatin
Vliianie razlichnykh rezhimov GBO na transkriptsionnuiu aktivnost' i morfologiiu neĭronov lobnoĭ kory pri okkliuzii obshcheĭ sonnoĭ arterii u krys.