title: Protein engineering.
abstract: Ten years of protein engineering have seen the synthesis of novel therapeutic agents and the analysis of the structure, activity, specificity, stability and folding pathways of proteins. It is hoped that protein engineering will eventually lead to the design of novel catalytic sites on either novel or existing proteins.
authors.affiliation: Cambridge University Chemical Laboratory, UK.
authors.forename: A
authors.initials: A
authors.lastname: Fersht
authors.forename: G
authors.initials: G
authors.lastname: Winter
mesh_terms: D002384:Catalysis; D007140:Immunoglobulin Fab Fragments / Q000737:chemistry; D011487:Protein Conformation; D015202:Protein Engineering; D013329:Structure-Activity Relationship; D013381:Subtilisins / Q000737:chemistry; D014448:Tyrosine-tRNA Ligase / Q000737:chemistry
chemical_list: D007140:Immunoglobulin Fab Fragments; D013381:Subtilisins; D014448:Tyrosine-tRNA Ligase