Localization of fibronectin in the initial lymphatics and blood vessels of normal human skin: an immunoelectron microscopic investigation.
The initial lymphatics of the human skin do not possess a basal lamina, but a subendothelial fibrous network, of which we do not know the biochemical and immunohistological composition. We investigated the wall of blood vessels and initial lymphatics in normal human skin for the presence of fibronectin by immunoelectron microscopy. We found discontinuous linear subendothelial diaminobenzidine (DAB) reaction products in both blood vessels and lymphatics. In addition fibronectin could be found at the anchoring fibrils of the initial lymphatics.
Lubach
D
D
Department of Dermatology (Hautklinik Linden) Medizinische Hochschule Hannover, Germany.
Nissen
S
S
Marghescu
S
S
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001808:Blood Vessels / Q000378:metabolism / Q000648:ultrastructure; D005260:Female; D005353:Fibronectins / Q000378:metabolism*; D006801:Humans; D008208:Lymphatic System / Q000378:metabolism / Q000648:ultrastructure; D008297:Male; D016253:Microscopy, Immunoelectron; D008875:Middle Aged; D012867:Skin / Q000378:metabolism* / Q000648:ultrastructure
D005353:Fibronectins