title: [A simple method of continuous passage of human tumors in immunocompetent mice].
abstract: A simple procedure is described for the continuous passage of a human tumor in immunocompetent mice. The BRO human melanoma was transplanted consecutively 25 times by implanting tumor tissue under the sub--renal capsule of mice which had been immunosuppressed by a single dose of whole--body irradiation or by cytosine arabinoside followed by irradiation. The tumor grew continuously for 14 days, and cytological examination showed that the growth consisted almost entirely of tumor cells.
authors.forename: A
authors.initials: A
authors.lastname: Lokshin
authors.forename: V I
authors.initials: VI
authors.lastname: Riabkova
authors.forename: V K
authors.initials: VK
authors.lastname: Sokolova
mesh_terms: D000818:Animals; D003561:Cytarabine / Q000494:pharmacology; D006801:Humans; D007121:Immunocompetence; D007165:Immunosuppression Therapy; D008546:Melanoma, Experimental / Q000276:immunology / Q000473:pathology; D051379:Mice; D008810:Mice, Inbred C57BL; D013997:Time Factors; D014183:Transplantation, Heterologous; D014407:Tumor Cells, Cultured / Q000276:immunology / Q000473:pathology; D014916:Whole-Body Irradiation
chemical_list: D003561:Cytarabine
vernacular_title: Prostoĭ metod dlia postoiannogo vyrashchivaniia opukholi cheloveka u immunokompetentnykh mysheĭ.