Preprotachykinin A mRNA detected by in situ hybridization in guinea pig vestibular ganglion.
In situ hybridization histochemistry was conducted to examine the expression of mRNA encoding preprotachykinin A (PPTA), the precursor of the neuropeptide substance P (SP) and neurokinin A (NKA), in guinea pig vestibular ganglion. Signals for PPTA mRNA moderately accumulated on most ganglion cells. SP and NKA are thus confirmed to be present in vestibular ganglion cells of the guinea pig.
Fujita
S
S
Department of Otorhinolaryngology, Hirosaki University School of Medicine, Japan.
Inagaki
S
S
Takagi
H
H
Asao
T
T
Hozawa
J
J
Usami
S
S
D000818:Animals; D006168:Guinea Pigs; D017403:In Situ Hybridization; D011498:Protein Precursors / Q000235:genetics*; D012333:RNA, Messenger / Q000032:analysis* / Q000235:genetics; D015320:Tachykinins / Q000235:genetics*; D014725:Vestibular Nerve / Q000737:chemistry*
D011498:Protein Precursors; D012333:RNA, Messenger; D015320:Tachykinins; C044206:preprotachykinin