title: [Ventricular function in hypertrophic cardiomyopathy. Systolic and diastolic ventricular function].
abstract: BASIC CONSIDERATION: Hypertrophic cardiomyopathy is defined as a primary myocardial disease associated with a hypertrophic non-dilated left ventricle with no other heart or systemic disease that might lead to hypertrophy of the left ventricle. The leading symptoms are effort-associated angina and dyspnea, rapid fatigue, dizziness and syncope.
  
  
  RESULTS
  The hemodynamic situation is characterized by a hyperdynamic systole and impaired diastole and left-ventricular filling. In the obstructive form, hypertrophy of the basal septum and an anteriorly moving mitral valve during systole result in an end-systolic reduction in the cross-section of the outflow tract associated with considerable intraventricular pressure gradients. Disturbances in the myocardial calcium metabolism are presently suspected to be causally involved in the diastolic function impairment.
authors.affiliation: Abteilung für Kardiologie, Universität Frankfurt.
authors.forename: H G
authors.initials: HG
authors.lastname: Olbrich
authors.forename: M
authors.initials: M
authors.lastname: Kaltenbach
authors.forename: R
authors.initials: R
authors.lastname: Hopf
mesh_terms: D002312:Cardiomyopathy, Hypertrophic / Q000503:physiopathology*; D003971:Diastole / Q000502:physiology; D006346:Heart Septum / Q000503:physiopathology; D006352:Heart Ventricles / Q000503:physiopathology; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D009200:Myocardial Contraction / Q000502:physiology*; D013599:Systole / Q000502:physiology
vernacular_title: Ventrikelfunktion bei hypertrophischer Kardiomyopathie. Systolische und diastolische Ventrikelfunktion.