title: 3-anilino-L-alanine, structural determination of UV-5, a contaminant in EMS-associated L-tryptophan samples.
abstract: An aniline derivative which corresponds to UV-5 in the preceding paper was isolated from the case L-tryptophan sample associated with eosinophilia-myalgia syndrome (EMS). By spectroscopic analyses, the structure was identified as 3-anilinoalanine. The compound was optically active, and the stereochemistry of alanine moiety was determined as L, by comparing the specific rotation with a synthesized 3-anilino-L-alanine.
authors.affiliation: National Institute of Hygienic Sciences (NIHS), Tokyo, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Goda
authors.forename: J
authors.initials: J
authors.lastname: Suzuki
authors.forename: T
authors.initials: T
authors.lastname: Maitani
authors.forename: K
authors.initials: K
authors.lastname: Yoshihira
authors.forename: M
authors.initials: M
authors.lastname: Takeda
authors.forename: M
authors.initials: M
authors.lastname: Uchiyama
mesh_terms: D000409:Alanine / Q000031:analogs & derivatives* / Q000032:analysis; D002851:Chromatography, High Pressure Liquid; D016603:Eosinophilia-Myalgia Syndrome / Q000097:blood*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D014364:Tryptophan / Q000097:blood*
chemical_list: C078798:3-(phenylamino)alanine; D014364:Tryptophan; D000409:Alanine