Adhesion cascades: diversity through combinatorial strategies.
Cell adhesion occurs via a highly regulated set of sequential interactions. Prototypic components of a variety of adhesion cascades are discussed, including integrins, triggering molecules and lectin-carbohydrate interactions. Selectivity and efficiency are achieved by utilizing the right combination of multiple adhesion molecules and by their coordinated biochemical regulation.
Schweighoffer
T
T
Human Immunology Section, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892.
Shaw
S
S
D000818:Animals; D002241:Carbohydrates / Q000502:physiology; D002448:Cell Adhesion / Q000502:physiology*; D006801:Humans; D016023:Integrins / Q000502:physiology; D037102:Lectins / Q000502:physiology
D002241:Carbohydrates; D016023:Integrins; D037102:Lectins