title: A study of the effect of Picolax on body weight, cardiovascular variables and haemoglobin concentration.
abstract: This study compared the effect of Picolax when administered for large bowel preparation in combination with preoperative fasting on body weight, haemoglobin concentration, haematocrit, and cardiovascular variables with matched subjects who were fasted before surgery. Picolax resulted in significantly greater weight loss, increases in haemoglobin concentration combined with cardiovascular changes suggesting hypovolaemia in the Picolax group. Intravenous fluid replacement is recommended in patients receiving Picolax.
authors.affiliation: University Department of Anaesthetics, Leicester General Hospital.
authors.forename: P
authors.initials: P
authors.lastname: Barker
authors.forename: T
authors.initials: T
authors.lastname: Trotter
authors.forename: C
authors.initials: C
authors.lastname: Hanning
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D001835:Body Weight / Q000187:drug effects*; D002400:Cathartics / Q000494:pharmacology*; D002951:Citrates; D003106:Colon / Q000601:surgery; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D006454:Hemoglobins / Q000187:drug effects*; D006801:Humans; D008875:Middle Aged; D009942:Organometallic Compounds; D010847:Picolines / Q000494:pharmacology*; D011300:Preoperative Care
chemical_list: D002400:Cathartics; D002951:Citrates; D006454:Hemoglobins; D009942:Organometallic Compounds; D010847:Picolines; C005701:picosulfate sodium