title: Major recurrent oral ulcers in AIDS: report of three cases.
abstract: We report the cases of three AIDS patients who developed major recurrent oral ulcers with severe odynophagia and weight loss. The patients were treated successfully with systemic steroids. Within the first week of prednisone therapy (40 mg/day), the symptoms improved and the lesions entirely healed. We suggest, on the bases of recent literature, that superantigens and the cytokine network could be involved and they should be considered in the immunopathogenic mechanisms of this type of ulcers.
authors.affiliation: Department of Infectious Diseases, Instituto Nacional de la Nutrición Salvador Zubirán, México City, México.
authors.forename: G
authors.initials: G
authors.lastname: Reyes-Terán
authors.forename: V
authors.initials: V
authors.lastname: Ramírez-Amador
authors.forename: E
authors.initials: E
authors.lastname: De la Rosa
authors.forename: M
authors.initials: M
authors.lastname: González-Guevara
authors.forename: S
authors.initials: S
authors.lastname: Ponce de León
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D003680:Deglutition Disorders / Q000209:etiology; D006801:Humans; D008297:Male; D010160:Palate, Soft / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use; D012008:Recurrence; D013281:Stomatitis, Aphthous / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
chemical_list: D011241:Prednisone