Screening for early ovarian cancer.
Transvaginal ultrasound scanning with colour Doppler imaging can be used to detect early ovarian cancer. About one in three women with a family history of the disease and a positive screening result (i.e. a persistent intraovarian mass with a characteristic blood supply) will have histological signs of primary cancer. A randomized controlled clinical trial should be undertaken to assess whether screening and immediate treatment of women from the general population will improve survival rates from the disease.
Bourne
T H
TH
King's College School of Medicine and Dentistry, London.
Hampson
J
J
Reynolds
K
K
Collins
W P
WP
Campbell
S
S
D015295:Antigens, Tumor-Associated, Carbohydrate / Q000097:blood; D014408:Biomarkers, Tumor / Q000097:blood; D002985:Clinical Protocols / Q000592:standards; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000379:methods / Q000592:standards*; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control*; D012307:Risk Factors; D012680:Sensitivity and Specificity; D014463:Ultrasonography; D014621:Vagina / Q000000981:diagnostic imaging
D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor