Prenatal presentation of congenital chloride diarrhea: clinical report and review of the literature.
A case of congenital chloride diarrhea was diagnosed after delivery in a patient whose antenatal course was notable for massively dilated small and large bowel and persistent, severe hydramnios refractory to therapy. The pathophysiologic mechanism is a dysfunctional chloride-bicarbonate exchange in the brush border of the ileum. Antenatal presentation, prenatal diagnosis, and a review of the current literature are discussed.
Rose
N C
NC
Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia 19104.
Kaplan
P
P
Scott
S
S
Kousoulis
A
A
Librizzi
R
R
D000328:Adult; D000649:Amniocentesis; D002712:Chlorides / Q000502:physiology; D003968:Diarrhea, Infantile / Q000151:congenital* / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007415:Intestinal Obstruction / Q000000981:diagnostic imaging / Q000209:etiology* / Q000601:surgery; D006831:Polyhydramnios / Q000150:complications* / Q000628:therapy; D011247:Pregnancy; D016216:Ultrasonography, Prenatal
D002712:Chlorides