title: Improvement of the exercise test after therapy in thyrotoxic periodic paralysis.
abstract: The diagnosis of periodic paralysis (PP) can be aided by demonstrating a decrease in compound motor action potential (CMAP) amplitude after several minutes of exercise. We report a case of secondary hypokalemic PP due to thyrotoxicosis in which the decrease in the CMAP amplitude after exercise dramatically improved after treatment, when a euthyroid state was achieved. The exercise test is a useful electrophysiologic means of monitoring the neuromuscular status of patients with thyrotoxic periodic paralysis prior to, and after treatment of the thyrotoxicosis.
authors.affiliation: Department of Medicine, University of Texas Health Science Center, San Antonio 78284-7883.
authors.forename: C E
authors.initials: CE
authors.lastname: Jackson
authors.forename: R J
authors.initials: RJ
authors.lastname: Barohn
mesh_terms: D000200:Action Potentials; D000328:Adult; D004576:Electromyography; D005080:Exercise Test; D006801:Humans; D007008:Hypokalemia / Q000209:etiology; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D009132:Muscles / Q000503:physiopathology; D010243:Paralysis / Q000175:diagnosis* / Q000209:etiology; D013971:Thyrotoxicosis / Q000150:complications* / Q000175:diagnosis / Q000532:radiotherapy
chemical_list: D007457:Iodine Radioisotopes