Sperm antibodies.
Anti-sperm antibodies (ASA) occur in 1% to 30% of infertile couples. Mechanisms by which ASA impair fertility include prevention of fertilization by decreasing acrosome reaction and/or zona pellucida binding, and postfertilization effects. Treatment for ASA involves assisted reproductive technologies.
Peters
A J
AJ
Center for Reproduction and Transplantation Immunology, Methodist Hospital, Indianapolis, Indiana.
Coulam
C B
CB
D000818:Animals; D000917:Antibody Formation; D005260:Female; D006801:Humans; D007246:Infertility / Q000209:etiology / Q000276:immunology* / Q000628:therapy; D008297:Male; D051379:Mice; D012698:Serologic Tests / Q000379:methods; D013083:Sperm Transport / Q000276:immunology; D013084:Sperm-Ovum Interactions / Q000276:immunology; D013094:Spermatozoa / Q000276:immunology*