[Lipid peroxidation in the aorta of normotensive and spontaneously hypertensive rats with diabetes mellitus].
We have studied the effects of streptozotocin-induced (STI) diabetes on the lipid peroxidation in the aorta from normotensive (NTR) and spontaneously hypertensive (SHR) rats. In the control SHR quantity of malonyldialdehyde (MDA), conjugated dienes (CD) and arterial pressure where higher than in NTR analogous group. It has been shown that Diabetes in NTR results in significantly increased arterial pressure and quantity of MDA and CD. Under certain conditions in SHR arterial pressure and the other factors remain almost unchanged. It is likely that completely different changes in intensity of lipid peroxidation may evidence breaking adaptation mechanism in diabetic SHR.
Vasil'eva
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D000818:Animals; D001011:Aorta / Q000378:metabolism*; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism*; D006801:Humans; D006973:Hypertension / Q000378:metabolism*; D007231:Infant, Newborn; D015227:Lipid Peroxidation; D051381:Rats; D011918:Rats, Inbred SHR; D011921:Rats, Inbred WKY
Perekisnoe okislenie lipidov v aorte normotenzivnykh i spontanno-gipertenzivnykh krys pri sakharnom diabete.