title: [Rapidly progressing glomerulonephritis with antibodies against cytoplasm of neutrophilic leukocytes].
abstract: The authors describe the clinical, laboratory and morphological findings, the clinical course and response to treatment in three patients with rapidly progressing glomerulonephritis where positive antibodies against the cytoplasm of neutrophil granulocytes (ANCA) were found. The authors confront their own clinical experience with data in the literature. Examination of ANCA is not only a significant contribution towards a more accurate diagnosis of renal vasculitis, but also an indicator of the activity of the disease and thus of the effectiveness of immunosuppressive treatment.
authors.affiliation: I. interní klinika 1. lékarské fakulty KU, Praha.
authors.forename: V
authors.initials: V
authors.lastname: Tesar
authors.forename: J
authors.initials: J
authors.lastname: Zabka
authors.forename: A
authors.initials: A
authors.lastname: Stejskalová
authors.forename: J
authors.initials: J
authors.lastname: Bartůnková
authors.forename: E
authors.initials: E
authors.lastname: Jelínková
authors.forename: I
authors.initials: I
authors.lastname: Rychlík
authors.forename: M
authors.initials: M
authors.lastname: Mokrejsová
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000032:analysis*; D003593:Cytoplasm / Q000276:immunology*; D005921:Glomerulonephritis / Q000276:immunology* / Q000473:pathology / Q000628:therapy; D006801:Humans; D007668:Kidney / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology*
chemical_list: D001323:Autoantibodies
vernacular_title: Rychle progredující glomerulonefritida s pozitivními protilátkami proti cytoplazmĕ neutrofilních leukocytů (ANCA).