[Specifics of changes in various groups of enzymes in rat cerebral cortex after interstrain transplantation of embryonal nerve tissue].
Embryonal nervous tissue from Wistar rats was transplanted into male rats of Wistar and August strains. Activity of eight enzymes belonging to various systems was estimated in brain cortex of rats recipients within 36 days after the transplantation. Lactate dehydrogenase, alanine aminotransferase, acid phosphatase, 5'-nucleotidase, ATPase and aldolase exhibited the dissimilarly decreased rate of activity in brain cortex of Wistar rats after transplantation as compared with the enzymatic activity in intact animals of this strain, while activity of alkaline phosphatase and esterases hydrolyzing alpha-naphthyl acetate was increased. Activation of almost all the enzymes studied was found within 36 days in Wistar rats after the transplantation. The rate of activity of zonal esterase isoenzymes was higher in brain cortex of August rats after transplantation of embryonal nervous tissue from Wistar strain as compared with that of Wistar to Wistar rats transplantation. The data obtained suggest that tissues of donors affected definitely the enzymatic activity in brain cells of rats-recipients as activity of most enzymes studied was higher in brain cortex of donors as compared with that of recipients.
Ivanov
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DE
Vitvitskiĭ
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VN
D015720:5'-Nucleotidase / Q000378:metabolism; D000135:Acid Phosphatase / Q000378:metabolism; D000410:Alanine Transaminase / Q000378:metabolism; D000818:Animals; D002540:Cerebral Cortex / Q000201:enzymology*; D004950:Esterases / Q000378:metabolism; D016332:Fetal Tissue Transplantation; D005634:Fructose-Bisphosphate Aldolase / Q000378:metabolism; D007527:Isoenzymes / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008297:Male; D009417:Nerve Tissue / Q000196:embryology / Q000637:transplantation*; D051381:Rats; D017208:Rats, Wistar; D013045:Species Specificity
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase; D000410:Alanine Transaminase; D004950:Esterases; D000135:Acid Phosphatase; D015720:5'-Nucleotidase; D005634:Fructose-Bisphosphate Aldolase
Spetsifika izmeneniĭ raznykh grupp fermentov v kore mozga krys posle mozhlineĭnoĭ transplantatsii émbrional'noĭ nervnoĭ tkani.