Expression of neuronal markers in the so-called ENU-induced schwannomas.
The present data show that the so-called ENU-induced malignant schwannomas express neuronal markers. This finding supports the hypothesis that a population of tumor cells in these neoplasms are neuroblastic in nature, and suggests the classification of ENU-induced schwannomas as primitive neuroectodermal tumors.
Vaquero
J
J
Neurosurgical Department, Puerta de Hierro Clinic, Autonomous University, San Martin de Porres, Madrid, Spain.
Coca
S
S
Zurita
M
M
Oya
S
S
Arias
A
A
Morales
C
C
D000818:Animals; D001369:Axons / Q000648:ultrastructure; D015415:Biomarkers; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D005038:Ethylnitrosourea; D005260:Female; D007124:Immunoenzyme Techniques; D008431:Maternal-Fetal Exchange; D008854:Microscopy, Electron; D009186:Myelin Sheath / Q000648:ultrastructure; D009442:Neurilemmoma / Q000139:chemically induced / Q000473:pathology* / Q000648:ultrastructure; D016900:Neurofilament Proteins / Q000032:analysis*; D011247:Pregnancy; D051381:Rats; D017208:Rats, Wistar; D012583:Schwann Cells / Q000473:pathology / Q000648:ultrastructure; D013120:Spinal Cord Neoplasms / Q000139:chemically induced / Q000473:pathology* / Q000648:ultrastructure; D016708:Synaptophysin / Q000032:analysis*
D015415:Biomarkers; D016900:Neurofilament Proteins; D016708:Synaptophysin; D005038:Ethylnitrosourea