title: Vitreon, a short-term vitreoretinal tamponade.
abstract: This investigation of the liquid perfluorocarbon, perfluorophenanthrene (Vitreon), establishes its safety and efficacy as a short-term vitreoretinal tamponade. We utilised Vitreon as an intraoperative tool and postoperative vitreoretinal tamponade in 16 patients. Proliferative vitreoretinopathy (PVR) (six), giant retinal tear (four), rhegmatogenous retinal detachment (three), retinal detachment with keratoprosthesis (two), and submacular and vitreous haemorrhage (one) were successfully repaired. Vitreon was left in the eye and removed 5 days to 4 weeks postoperatively. Complications encountered included proliferative PVR (five), limited peripheral retinal detachment (three), macular pucker (two) cataract (three), hypotony (two), excessive fibrin reaction (one), and elevated intraocular pressure (one). At the latest evaluation, all retinas are attached with a follow-up of 1.25 to 12 months (mean 6.8 months).
authors.affiliation: Louisiana State University Medical Center School of Medicine, New Orleans 70112.
authors.forename: K J
authors.initials: KJ
authors.lastname: Blinder
authors.forename: G A
authors.initials: GA
authors.lastname: Peyman
authors.forename: U R
authors.initials: UR
authors.lastname: Desai
authors.forename: N C
authors.initials: NC
authors.lastname: Nelson
authors.forename: W
authors.initials: W
authors.lastname: Alturki
authors.forename: C L
authors.initials: CL
authors.lastname: Paris
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004341:Drug Evaluation; D005128:Eye Diseases / Q000601:surgery*; D005260:Female; D005466:Fluorocarbons / Q000008:administration & dosage*; D005500:Follow-Up Studies; D006801:Humans; D007430:Intraoperative Care / Q000379:methods; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care / Q000379:methods; D012160:Retina / Q000601:surgery*; D012164:Retinal Diseases / Q000601:surgery; D014822:Vitreous Body / Q000601:surgery*
chemical_list: D005466:Fluorocarbons; C047722:perfluorophenanthrene