title: Bartter's syndrome with gouty arthritis.
abstract: A 45-year-old woman with Bartter's syndrome complicated with gouty arthritis is reported. Bartter's syndrome was diagnosed from hypokalemia, metabolic alkalosis, high plasma renin activity, normal blood pressure and attenuated pressor response to exogenous angiotensin II infusion. Serum uric acid was 11.8 mg/dl, the renal clearance of uric acid was low (3.0 ml/min) and fractional excretion of uric acid (FEUA) was 7.0%, being the lower limit of the normal range. Fractional excretion of phosphate was low (5.3%) and fractional free water clearance per fractional distal sodium delivery was 0.51. The mechanism of hyperuricemia in this case is discussed.
authors.affiliation: Department of Internal Medicine, Oji General Hospital, Tomakomai, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ogawa
authors.forename: Y
authors.initials: Y
authors.lastname: Fujise
authors.forename: S
authors.initials: S
authors.lastname: Shibata
authors.forename: M
authors.initials: M
authors.lastname: Abiru
authors.forename: Y
authors.initials: Y
authors.lastname: Takigami
authors.forename: T
authors.initials: T
authors.lastname: Miura
authors.forename: K
authors.initials: K
authors.lastname: Kikuchi
authors.forename: Y
authors.initials: Y
authors.lastname: Fukazawa
authors.forename: O
authors.initials: O
authors.lastname: Iimura
mesh_terms: D015210:Arthritis, Gouty / Q000209:etiology*; D001477:Bartter Syndrome / Q000150:complications* / Q000378:metabolism; D005260:Female; D006801:Humans; D007684:Kidney Tubules / Q000503:physiopathology; D008875:Middle Aged; D012084:Renin-Angiotensin System; D014511:Uremia / Q000209:etiology; D014527:Uric Acid / Q000097:blood / Q000378:metabolism
chemical_list: D014527:Uric Acid