The clinical spectrum of chronic appendiceal abscess in cystic fibrosis.
OBJECTIVE
To describe the varied characteristics seen in patients with cystic fibrosis who develop chronic abscess formation secondary to unrecognized appendicitis.


METHODS
Patient series.


METHODS
Cystic Fibrosis Care Centers in Columbus, Ohio, and Tucson, Ariz.


METHODS
Five patients with cystic fibrosis who developed chronic abdominal abscesses secondary to occult appendicitis are described. Two patients developed fistula formation with purulent fluid drainage before diagnosis. One patient developed an extensive psoas abscess. Another presented with prolonged fever of unknown origin. These patients were identified by retrospective review of the past 20-year experience at two Cystic Fibrosis Care Centers.


CONCLUSIONS
Development of chronic abdominal abscess related to unrecognized appendicitis is a rare but important complication in patients with cystic fibrosis. Prompt diagnosis depends on physician familiarity with the varied presentations of this entity. Diagnostic abdominal computed tomography and/or ultrasonography should particularly be considered when patients with cystic fibrosis present with pain, mass, or drainage from the right flank; prolonged fever; a limp; or failure of suspected meconium ileus equivalent syndrome to respond promptly to cathartic measures.
Allen
E D
ED
Department of Pediatrics, Ohio State University, Columbus.
Pfaff
J K
JK
Taussig
L M
LM
McCoy
K S
KS
D000038:Abscess / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D000293:Adolescent; D000328:Adult; D001064:Appendicitis / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D001130:Arizona; D002648:Child; D002908:Chronic Disease; D003550:Cystic Fibrosis / Q000150:complications*; D003672:Defecation; D005260:Female; D006782:Hospitals, Special; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D009820:Ohio; D010808:Physical Examination; D014057:Tomography, X-Ray Computed