[Ventricular function in hypertrophic cardiomyopathy. Systolic and diastolic ventricular function].
BASIC CONSIDERATION: Hypertrophic cardiomyopathy is defined as a primary myocardial disease associated with a hypertrophic non-dilated left ventricle with no other heart or systemic disease that might lead to hypertrophy of the left ventricle. The leading symptoms are effort-associated angina and dyspnea, rapid fatigue, dizziness and syncope.


RESULTS
The hemodynamic situation is characterized by a hyperdynamic systole and impaired diastole and left-ventricular filling. In the obstructive form, hypertrophy of the basal septum and an anteriorly moving mitral valve during systole result in an end-systolic reduction in the cross-section of the outflow tract associated with considerable intraventricular pressure gradients. Disturbances in the myocardial calcium metabolism are presently suspected to be causally involved in the diastolic function impairment.
Olbrich
H G
HG
Abteilung für Kardiologie, Universität Frankfurt.
Kaltenbach
M
M
Hopf
R
R
D002312:Cardiomyopathy, Hypertrophic / Q000503:physiopathology*; D003971:Diastole / Q000502:physiology; D006346:Heart Septum / Q000503:physiopathology; D006352:Heart Ventricles / Q000503:physiopathology; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D009200:Myocardial Contraction / Q000502:physiology*; D013599:Systole / Q000502:physiology
Ventrikelfunktion bei hypertrophischer Kardiomyopathie. Systolische und diastolische Ventrikelfunktion.