title: Accessory spleen in recurrent chronic immune thrombocytopenic purpura.
abstract: From 1969 to 1985 we discovered accessory spleens in 8 patients with chronic immune thrombocytopenic purpura (ITP) who relapsed or failed after splenectomy. Imaging of accessory spleen used a liver spleen scintigraphy with heat-treated RBC labeled with Tc-99m. Platelet kinetic studies with 51Cr or 111In, including sequestration index, were performed. Five patients had accessory splenectomy. Disappearance of bleeding symptoms was achieved in the 5 splenectomized patients but with only partial response of platelet counts. These results are discussed in the context of diagnosis and therapeutic management of accessory spleens in patients with chronic immune thrombocytopenic purpura who relapsed or failed after splenectomy.
authors.affiliation: Service des Maladies du Sang, C.H.U. Lille, France.
authors.forename: T
authors.initials: T
authors.lastname: Facon
authors.forename: M T
authors.initials: MT
authors.lastname: Caulier
authors.forename: P
authors.initials: P
authors.lastname: Fenaux
authors.forename: I
authors.initials: I
authors.lastname: Plantier
authors.forename: X
authors.initials: X
authors.lastname: Marchandise
authors.forename: M
authors.initials: M
authors.lastname: Ribet
authors.forename: J P
authors.initials: JP
authors.lastname: Jouet
authors.forename: F
authors.initials: F
authors.lastname: Bauters
mesh_terms: D000293:Adolescent; D000328:Adult; D001792:Blood Platelets; D002648:Child; D002675:Child, Preschool; D002860:Chromium Radioisotopes; D002908:Chronic Disease; D005260:Female; D006801:Humans; D015994:Incidence; D007205:Indium Radioisotopes; D008297:Male; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000453:epidemiology / Q000601:surgery*; D011877:Radionuclide Imaging; D012008:Recurrence; D013154:Spleen / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology; D013156:Splenectomy; D013158:Splenic Diseases / Q000150:complications* / Q000175:diagnosis
chemical_list: D002860:Chromium Radioisotopes; D007205:Indium Radioisotopes