title: Evaluation of the teicoplanin broth microdilution and disk diffusion susceptibility tests and recommended interpretive criteria.
abstract: Comparative teicoplanin in vitro susceptibility data were generated for 1201 Gram-positive US clinical trial isolates using standardized broth microdilution and disk diffusion techniques. Based on the results of this study, the following interpretive criteria for teicoplanin are recommended: for MIC tests, less than or equal to 8 micrograms/ml = susceptible, 16 micrograms/ml = moderately susceptible, and greater than or equal to 32 micrograms/ml = resistant; and for disk (30 micrograms) tests, greater than or equal to 14 mm = susceptible, 11-13 mm = intermediate, and less than or equal to 10 mm = resistant.
authors.affiliation: Marion Merrell Dow Research Institute, Indianapolis, IN 46368-0470.
authors.forename: M T
authors.initials: MT
authors.lastname: Kenny
authors.forename: G D
authors.initials: GD
authors.lastname: Mayer
authors.forename: J K
authors.initials: JK
authors.lastname: Dulworth
authors.forename: M A
authors.initials: MA
authors.lastname: Brackman
authors.forename: K
authors.initials: K
authors.lastname: Farrar
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D005069:Evaluation Studies as Topic; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods; D017334:Teicoplanin / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D017334:Teicoplanin