title: Optimization schemes for selective excitations: application to the DIGGER pulses.
abstract: In this work, two distinct approaches to the tailoring of selective radiofrequency (RF) pulses were applied to a cos-sinc pulse of the DIGGER sequence used in localized spectroscopy. Ideally, three such pulses combined with a gradient in each direction destroy the Mz component of the magnetization everywhere but in the volume of interest. In the first approach, the optimal RF amplitude modulation is found by minimizing the difference between the ideal and the computed Mz profiles. In the second strategy, the RF pulse envelope is adjusted by optimization of the tip angle profile. Computed slice profiles optimized by each of these methods have been compared to experimental results. Simulations as well as experiments show that the second approach, which optimizes tip angles, is the most efficient.
authors.affiliation: Department of Organic Chemistry, State University of Mons, Belgium.
authors.forename: A
authors.initials: A
authors.lastname: Roch
authors.forename: H H
authors.initials: HH
authors.lastname: Raeymaekers
authors.forename: L
authors.initials: L
authors.lastname: Lamalle
authors.forename: Y
authors.initials: Y
authors.lastname: van Haverbeke
authors.forename: R N
authors.initials: RN
authors.lastname: Muller
mesh_terms: D009682:Magnetic Resonance Spectroscopy / Q000379:methods*