Analysis of purine nucleotides in lymphocytes from healthy subjects and AIDS patients.
The most important purine nucleotides (NAD, AMP, IMP, GMP, XMP, ADP, ATP, GDP, GTP) were analyzed by HPLC in the lymphocytes of healthy subjects and HIV-1 seropositive patients at different stages of the disease (ARC-AIDS). Several differences, which focus attention on the behaviour of purine nucleotide metabolism in the lymphocytes of these patients, were observed.
Tabucchi
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Istituto di Biochimica e di Enzimologia, Università di Siena, Italy.
Carlucci
F
F
Ramazzotti
E
E
Re
M C
MC
Marinello
F
F
Rubino
M
M
Pagani
R
R
D000386:AIDS-Related Complex / Q000453:epidemiology / Q000378:metabolism*; D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology / Q000378:metabolism*; D000328:Adult; D002851:Chromatography, High Pressure Liquid; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000166:cytology*; D008297:Male; D008875:Middle Aged; D011685:Purine Nucleotides / Q000032:analysis*
D011685:Purine Nucleotides