Behaviour of mouse macrophage cell line and mouse fibroblast on copolymers containing cellulose triacetate.
Copolymers containing cellulose triacetate were prepared under various conditions. A bacteriological plastic dish was coated with the copolymer (HCTA-MDI copolymer) composed of hydrolysed cellulose triacetate (HCTA) and diphenylmethane diisocyanate (MDI). The deacetylated copolymer (DA-copolymer) was prepared by the deacetylation of HCTA-MDI copolymer. The behaviour of animal cells such as a mouse macrophage cell line (A640-BB-2 cells) and a mouse fibroblast (3T6 cells) on prepared dishes was investigated morphologically. A640-BB-2 cells showed good adhesion and smooth spreading, and 3T6 cells also showed good adhesion and sufficient cell growth on the dish coated with HCTA-MDI copolymer. These results suggest that these copolymers are useful for biomedical materials.
Shigemasa
Y
Y
Department of Materials Science, Faculty of Engineering, Tottori University, Japan.
Sashiwa
H
H
Tanioka
S
S
Saimito
H
H
Tanigawa
T
T
Tanaka
Y
Y
D000818:Animals; D002448:Cell Adhesion; D002455:Cell Division; D002460:Cell Line; D002482:Cellulose / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D003485:Cyanates / Q000737:chemistry; D005347:Fibroblasts / Q000166:cytology*; D006868:Hydrolysis; D017953:Isocyanates; D007700:Kinetics; D008264:Macrophages / Q000166:cytology*; D051379:Mice; D008807:Mice, Inbred BALB C; D011108:Polymers; D001559:Benzhydryl Compounds
D002482:Cellulose; D003485:Cyanates; D017953:Isocyanates; D011108:Polymers; C024671:cellulose triacetate; C005969:4,4'-diphenylmethane diisocyanate; D001559:Benzhydryl Compounds