title: Influence of posture on mechanical parameters derived from respiratory impedance.
abstract: The influence of posture on respiratory mechanics was investigated in 10 healthy volunteers, using the forced pseudorandom noise technique. Subjects were studied in four randomly selected positions: sitting; sitting with the head turned sideways; supine; and prone with the head turned sideways. Respiratory compliance (Crs), inertance (Irs) and resistance estimated at 4 Hz (R4), were calculated by fitting respiratory impedance by a 4 parameter model with a frequency dependent resistance. When subjects changed from sitting to lying, whilst maintaining the head in the same position in relation to the body, Irs increased and Crs decreased, probably due to gravitational effects. R4 was significantly higher in the supine position than in either of the sitting or the prone positions. These results demonstrate that changes in lung volume cannot completely explain the influence of posture on respiratory resistance, and indicate upper airway geometry as a determinant factor of respiratory resistance.
authors.affiliation: INSERM U296, Département de Physiologie, Hôpital Henri Mondor, Créteil, France.
authors.forename: A M
authors.initials: AM
authors.lastname: Lorino
authors.forename: G
authors.initials: G
authors.lastname: Atlan
authors.forename: H
authors.initials: H
authors.lastname: Lorino
authors.forename: D
authors.initials: D
authors.lastname: Zanditenas
authors.forename: A
authors.initials: A
authors.lastname: Harf
mesh_terms: D000293:Adolescent; D000328:Adult; D000403:Airway Resistance; D005260:Female; D005583:Fourier Analysis; D006801:Humans; D008170:Lung Compliance; D008297:Male; D011187:Posture / Q000502:physiology*; D016684:Prone Position / Q000502:physiology; D015656:Respiratory Mechanics / Q000502:physiology*; D016683:Supine Position / Q000502:physiology