Veralipride-induced tardive dystonia in a patient with bipolar psychosis.
Veralipride is a benzamide derivative effective in the treatment of menopausal syndrome. Despite its antidopaminergic action, extrapyramidal side effects seem to be very uncommon. We observed a patient with bipolar psychosis, who developed segmental dystonia after taking the drug. The disorder slowly receded in 14 months, but reappeared during neuroleptic therapy a few months later. To the best of our knowledge, this is the first case of veralipride-induced tardive dystonia, and the affective disorder might have predisposed our patient to the development of this tardive side effect.
Gabellini
A S
AS
Servizio di Neurologia, Ospedale Maggiore di Bologna.
Pezzoli
A
A
De Massis
P
P
Sacquegna
T
T
D004421:Dystonia / Q000139:chemically induced*; D005260:Female; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D011618:Psychotic Disorders / Q000150:complications; D013469:Sulpiride / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use
D013469:Sulpiride; C027429:veralipride