title: Influence of melatonin on reproductive behavior in male rats.
abstract: The influence of melatonin on reproductive behavior was examined by administering it to pinealectomized male rats for 30 consecutive days. After the 30-d administration of melatonin or vehicle, each male rat was introduced into a female rat's cage on the day of proestrus and allowed to mate overnight. All rats administered the vehicle and the pinealectomized rats copulated; five of the twelve melatonin (8.0 mg/kg)-treated rats did not copulate. These findings suggest that melatonin inhibits the reproductive behavior of male rats.
authors.affiliation: Laboratory for Pharmaceutical Education, Tokyo College of Pharmacy, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Yamada
authors.forename: K
authors.initials: K
authors.lastname: Maruyama
authors.forename: S
authors.initials: S
authors.lastname: Mogami
authors.forename: N
authors.initials: N
authors.lastname: Miyagawa
authors.forename: M
authors.initials: M
authors.lastname: Tsuboi
mesh_terms: D000818:Animals; D005260:Female; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D011247:Pregnancy; D051381:Rats; D017208:Rats, Wistar; D012726:Sexual Behavior, Animal / Q000187:drug effects*
chemical_list: D008550:Melatonin