Loxoscelism.
Loxoscelism, or envenomation by the brown recluse spider, may result in necrotic lesions and systemic reactions, including hemolytic anemia. Histologically, it resembles a cutaneous Arthus reaction. The reaction mechanism involves interactions between complement, neutrophils, and the clotting system. It is best treated with analgesics, avoidance of early surgical debridement, and oral dapsone.
Futrell
J M
JM
Tulane University Medical School, Department of Dermatology, New Orleans, Louisiana 70112.
D000818:Animals; D006801:Humans; D001098:Spider Bites / Q000503:physiopathology* / Q000517:prevention & control / Q000628:therapy; D013112:Spiders