Effect of Galphimia glauca methanolic extract on neuropharmacological tests.
Galphimia glauca Cav. (Malpighiaceae) is used in Mexican traditional medicine for the treatment of nervous excitement. A methanolic extract from its aerial parts (MEGA) was tested in several neuropharmacological animal models including among others: hypothermic activity, barbiturate potentiation, protection against strychnine- and leptazol-induced convulsions. The combined data obtained from all biological models demonstrate the sedative property of this plant product.
Tortoriello
J
J
Traditional Medicine and Drug Development Research Unit, Mexican Institute of Social Security, IMSS.
Lozoya
X
X
D000818:Animals; D006993:Hypnotics and Sedatives / Q000494:pharmacology*; D008297:Male; D009420:Nervous System / Q000187:drug effects*; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D051381:Rats; D017208:Rats, Wistar
D006993:Hypnotics and Sedatives; D010936:Plant Extracts