title: [The protective activity of preparations made from the tick-borne encephalitis virus grown using different cell cultures].
abstract: The preparations of tick-borne encephalitis (TBE) virus grown in swine embryo kidney cell culture have been shown to possess pronounced protective activity per unit of virion protein E in comparison with TBE virus preparations derived from cell culture 4647 and chick embryo cell culture. The antigenic activity of all virus preparations under study has proved to be practically the same. The role of post-translation modifications of TBE virus protein E in the manifestation of some of its biological properties is discussed.
authors.forename: L B
authors.initials: LB
authors.lastname: El'bert
authors.forename: M F
authors.initials: MF
authors.lastname: Vorovich
authors.forename: E N
authors.initials: EN
authors.lastname: Terletskaia
authors.forename: E A
authors.initials: EA
authors.lastname: Lisitsina
authors.forename: S N
authors.initials: SN
authors.lastname: Atanadze
authors.forename: I G
authors.initials: IG
authors.lastname: Sidorovich
authors.forename: V V
authors.initials: VV
authors.lastname: Khozinskiĭ
authors.forename: Sh M
authors.initials: ShM
authors.lastname: Tugizov
authors.forename: A A
authors.initials: AA
authors.lastname: Kushch
authors.forename: Iu Kh
authors.initials: IuKh
authors.lastname: Khapchaev
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D002478:Cells, Cultured; D002642:Chick Embryo; D002522:Chlorocebus aethiops; D004669:Encephalitis Viruses, Tick-Borne / Q000254:growth & development / Q000276:immunology*; D007114:Immunization; D015151:Immunoblotting; D007124:Immunoenzyme Techniques; D051379:Mice; D008807:Mice, Inbred BALB C; D013552:Swine; D015164:Vaccines, Inactivated / Q000276:immunology / Q000302:isolation & purification; D014759:Viral Envelope Proteins / Q000276:immunology / Q000302:isolation & purification; D014764:Viral Proteins / Q000276:immunology / Q000302:isolation & purification; D014765:Viral Vaccines / Q000276:immunology* / Q000302:isolation & purification; D014776:Virus Cultivation / Q000379:methods
chemical_list: D000956:Antigens, Viral; D015164:Vaccines, Inactivated; D014759:Viral Envelope Proteins; D014764:Viral Proteins; D014765:Viral Vaccines; C065696:glycoprotein E, Flavivirus
vernacular_title: Izuchenie protektivnoĭ aktivnosti preparatov iz virusa kleshchevogo éntsefalita, vyrashchennogo s ispol'zovaniem razlichnykh kletochnykh kul'tur.