[Changes in EEG and higher nervous activity of rats during cerebral anti-ischemic protection by acelysin].
The water-soluble aspirin (acelysin) has been used as an anti-ischaemic protector when injected in the dose of 150 mg/kg 30 min before ischaemia. The EEG has been registered during the whole period of experiment and the total EEG power index has been calculated. The higher nervous activity has been evaluated during analysis of rat's abilities for elaboration of conditional reflex of an active escape reaction in Y-labyrinth. The results have demonstrated the complete rehabilitation and restoration of brain functional activity 8 days after endurance of brain ischaemia under protection of acelisin.
Tel'pukhov
V I
VI
Bilenko
M V
MV
Khokhlov
A V
AV
Komarov
P G
PG
D000818:Animals; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000494:pharmacology*; D001241:Aspirin / Q000031:analogs & derivatives*; D001921:Brain / Q000187:drug effects*; D002545:Brain Ischemia / Q000517:prevention & control*; D003214:Conditioning, Classical; D004338:Drug Combinations; D004569:Electroencephalography; D004924:Escape Reaction; D005998:Glycine; D006613:Higher Nervous Activity; D008239:Lysine / Q000031:analogs & derivatives*; D051381:Rats; D017208:Rats, Wistar; D012815:Signal Processing, Computer-Assisted; D013997:Time Factors
D000890:Anti-Infective Agents; D004338:Drug Combinations; C076488:acetylsalicylate, glycine, lysine drug combination; D008239:Lysine; D001241:Aspirin; D005998:Glycine
Izmenenie EEG i VID krys pri ispol'zovanii dlia protivoishemicheskoĭ zashchity golovnogo mozga atselizina.