title: 7,8-Dihydro-8-ethyl-2-(3-noradamantyl)-4-propyl-1H-imidazo[2,1-i]purin-5(4H)-one: a potent and water-soluble adenosine A1 antagonist.
authors.affiliation: Pharmaceutical Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Shizuoka-ken, Japan.
authors.forename: F
authors.initials: F
authors.lastname: Suzuki
authors.forename: J
authors.initials: J
authors.lastname: Shimada
authors.forename: H
authors.initials: H
authors.lastname: Nonaka
authors.forename: A
authors.initials: A
authors.lastname: Ishii
authors.forename: S
authors.initials: S
authors.lastname: Shiozaki
authors.forename: S
authors.initials: S
authors.lastname: Ichikawa
authors.forename: E
authors.initials: E
authors.lastname: Ono
mesh_terms: D000218:Adamantane / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology; D000241:Adenosine / Q000031:analogs & derivatives / Q000494:pharmacology; D019830:Adenosine-5'-(N-ethylcarboxamide); D000818:Animals; D006168:Guinea Pigs; D006439:Hemodynamics / Q000187:drug effects; D007093:Imidazoles / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D058914:Purinergic Antagonists; D011688:Purinones / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D051381:Rats; D011983:Receptors, Purinergic / Q000378:metabolism; D012995:Solubility; D014665:Vasodilator Agents / Q000494:pharmacology
chemical_list: D007093:Imidazoles; D058914:Purinergic Antagonists; D011688:Purinones; D011983:Receptors, Purinergic; D014665:Vasodilator Agents; C076920:KF 20274; D019830:Adenosine-5'-(N-ethylcarboxamide); D000241:Adenosine; D000218:Adamantane