title: HB Al-Ain Abu Dhabi [alpha 18(A16)Gly----Asp]: a new hemoglobin variant discovered in an Emiratee family.
abstract: During a routine program of hemoglobin screening performed in the United Arab Emirates, we observed an electrophoretically fast-moving variant in a 9-month-old girl and in several members of her family. The structural determination, performed by reversed phase high performance liquid chromatography and amino acid sequencing, revealed a new variant that we named Hb Al-Ain Abu Dhabi [alpha 18(A16) Gly----Asp]. Its functional properties were normal.
authors.affiliation: Department of Biology, Faculty of Sciences, United Arab Emirates University, Al-Ain.
authors.forename: S
authors.initials: S
authors.lastname: Abbes
authors.forename: A
authors.initials: A
authors.lastname: M'Rad
authors.forename: P A
authors.initials: PA
authors.lastname: Fitzgerald
authors.forename: P
authors.initials: P
authors.lastname: Dormer
authors.forename: Y
authors.initials: Y
authors.lastname: Blouquit
authors.forename: J
authors.initials: J
authors.lastname: Kister
authors.forename: F
authors.initials: F
authors.lastname: Galacteros
authors.forename: H
authors.initials: H
authors.lastname: Wajcman
mesh_terms: D000595:Amino Acid Sequence; D004586:Electrophoresis; D005260:Female; D014644:Genetic Variation / Q000235:genetics*; D006455:Hemoglobins, Abnormal / Q000737:chemistry / Q000235:genetics*; D006801:Humans; D007223:Infant; D008403:Mass Screening; D014479:United Arab Emirates / Q000453:epidemiology
chemical_list: D006455:Hemoglobins, Abnormal; C077660:hemoglobin Al-Ain-Abu Dhabi