title: Membrane transport proteins: implications of sequence comparisons.
abstract: Analyses of the sequences and structures of many transport proteins that differ in substrate specificity, direction of transport and mechanism of transport suggest that they form a family of related proteins. Their sequence similarities imply a common mechanism of action. This hypothesis provides an objective basis for examining their mechanisms of action and relationships to other transporters.
authors.affiliation: University of New Mexico.
authors.forename: J K
authors.initials: JK
authors.lastname: Griffith
authors.forename: M E
authors.initials: ME
authors.lastname: Baker
authors.forename: D A
authors.initials: DA
authors.lastname: Rouch
authors.forename: M G
authors.initials: MG
authors.lastname: Page
authors.forename: R A
authors.initials: RA
authors.lastname: Skurray
authors.forename: I T
authors.initials: IT
authors.lastname: Paulsen
authors.forename: K F
authors.initials: KF
authors.lastname: Chater
authors.forename: S A
authors.initials: SA
authors.lastname: Baldwin
authors.forename: P J
authors.initials: PJ
authors.lastname: Henderson
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001692:Biological Transport / Q000502:physiology; D002352:Carrier Proteins / Q000737:chemistry*; D006801:Humans; D008565:Membrane Proteins / Q000737:chemistry*; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid
chemical_list: D002352:Carrier Proteins; D008565:Membrane Proteins