Severe myelodysplasia with monosomies 5 and 7 presenting with rapidly fatal Sweet's syndrome.
A 57 year-old Chinese man with anaemia and thrombocytopenia due to monosomies 5 and 7-associated myelodysplasia developed progressive Sweet's syndrome. Recurrent episodes of cutaneous manifestations responded dramatically to corticosteroid therapy. However, progressive pulmonary infiltrates unresponsive to antimicrobial therapy resulted in respiratory failure and death.
Kueh
Y K
YK
Department of Medicine, National University of Singapore, Singapore.
Vijayasingam
S M
SM
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D002895:Chromosomes, Human, Pair 5; D002897:Chromosomes, Human, Pair 7; D006801:Humans; D008297:Male; D008875:Middle Aged; D009006:Monosomy; D009190:Myelodysplastic Syndromes / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D011877:Radionuclide Imaging; D012131:Respiratory Insufficiency / Q000209:etiology / Q000401:mortality; D016463:Sweet Syndrome / Q000150:complications* / Q000175:diagnosis* / Q000401:mortality
D000305:Adrenal Cortex Hormones