title: A prospective cytogenetic study of 36 cases of DiGeorge syndrome.
abstract: Cytogenetic analysis was carried out in a prospective series of 36 children with DiGeorge syndrome. High-resolution banding (> 850 bands/haploid set) was achieved in 30 cases. Monosomy 22q11.21-->q11.23 was found in 9 of these 30 cases. In each of these cases monosomy 22q11.21-->q11.23 resulted from an interstitial deletion and not from a translocation. No other chromosome abnormalities were seen.
authors.affiliation: Division of Human Genetics, University of Newcastle upon Tyne, U.K.
authors.forename: D I
authors.initials: DI
authors.lastname: Wilson
authors.forename: I E
authors.initials: IE
authors.lastname: Cross
authors.forename: J A
authors.initials: JA
authors.lastname: Goodship
authors.forename: J
authors.initials: J
authors.lastname: Brown
authors.forename: P J
authors.initials: PJ
authors.lastname: Scambler
authors.forename: H H
authors.initials: HH
authors.lastname: Bain
authors.forename: J F
authors.initials: JF
authors.lastname: Taylor
authors.forename: K
authors.initials: K
authors.lastname: Walsh
authors.forename: A
authors.initials: A
authors.lastname: Bankier
authors.forename: J
authors.initials: J
authors.lastname: Burn
mesh_terms: D002648:Child; D002675:Child, Preschool; D002872:Chromosome Deletion; D002892:Chromosomes, Human, Pair 22; D004062:DiGeorge Syndrome / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D009006:Monosomy; D011446:Prospective Studies