A new acylated N-glycosyl lactam from Aristolochia contorta.
A new acylated glycoside isolated from the roots of Aristolochia contorta (Aristolochiaceae), has been characterized as aristolactam N-(6'-trans-p-coumaroyl)-beta-D-glucopyranoside [2]. Aristolactam-N-beta-D-glucopyanoside [1] was also isolated from the same source. Compound 2 showed relatively significant antibacterial activity against Gram-positive bacteria, based on disc diffusion and dilution methods.
Lee
H S
HS
College of Pharmacy, Seoul National University, Korea.
Han
D S
DS
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D034341:Aristolochic Acids; D001419:Bacteria / Q000187:drug effects; D002701:Chloramphenicol / Q000494:pharmacology; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D007769:Lactams; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D010616:Phenanthrenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D034341:Aristolochic Acids; D005960:Glucosides; D007769:Lactams; D010616:Phenanthrenes; C078102:N-((6'-p-coumaroyl)glucopyranosyl)aristolactam; D002701:Chloramphenicol