[Intravenous immunoglobulins and anti-idiotypic suppression of auto-immunity].
This review summarizes the clinical use of intravenous immunoglobulins (IVIg) in autoimmune diseases and focuses on the mechanisms by which IVIg suppress autoimmune responses. Evidence is presented of a role of IVIg in modulating the regulatory function of the idiotypic network on the expression of the natural and pathological autoimmune repertoires.
Jobin
D
D
Service d'Immunologie, Hôpital Broussais, Paris.
Kazatchkine
M
M
D001323:Autoantibodies / Q000276:immunology; D001327:Autoimmune Diseases / Q000628:therapy*; D006801:Humans; D007116:Immunization, Passive; D007130:Immunoglobulin Idiotypes / Q000276:immunology*; D007136:Immunoglobulins / Q000008:administration & dosage; D007275:Injections, Intravenous
D001323:Autoantibodies; D007130:Immunoglobulin Idiotypes; D007136:Immunoglobulins
Immunoglobulines intraveineuses (IVIg) et suppression anti-idiotypique de l'auto-immunité.