title: Synthesis of 6-substituted tetrazolo[1,5-c]pyrimidin-5(6H)ones: new modification of 3'-azido-3'-deoxythymidine.
abstract: An efficient method for the preparation of 6-methyltetrazolo-[1,5-c]pyrimidin-5(6H)ones using as the precursors 4-chloro-1,2-dihydro-1-methyl-2-oxopyrimidines is described. The method is also extended to the synthesis of novel tetrazole analogue of 3'-azido-3'-deoxythymidine (AZT).
authors.affiliation: Faculty of Chemistry, Adam Mickiewicz University, Poznan, Poland.
authors.forename: K
authors.initials: K
authors.lastname: Ciszewski
authors.forename: L
authors.initials: L
authors.lastname: Celewicz
authors.forename: K
authors.initials: K
authors.lastname: Golankiewicz
mesh_terms: D001393:Azoles / Q000737:chemistry; D011744:Pyrimidinones / Q000737:chemistry; D015215:Zidovudine / Q000031:analogs & derivatives* / Q000138:chemical synthesis
chemical_list: D001393:Azoles; D011744:Pyrimidinones; D015215:Zidovudine