Membrane transport proteins: implications of sequence comparisons.
Analyses of the sequences and structures of many transport proteins that differ in substrate specificity, direction of transport and mechanism of transport suggest that they form a family of related proteins. Their sequence similarities imply a common mechanism of action. This hypothesis provides an objective basis for examining their mechanisms of action and relationships to other transporters.
Griffith
J K
JK
University of New Mexico.
Baker
M E
ME
Rouch
D A
DA
Page
M G
MG
Skurray
R A
RA
Paulsen
I T
IT
Chater
K F
KF
Baldwin
S A
SA
Henderson
P J
PJ
D000595:Amino Acid Sequence; D000818:Animals; D001692:Biological Transport / Q000502:physiology; D002352:Carrier Proteins / Q000737:chemistry*; D006801:Humans; D008565:Membrane Proteins / Q000737:chemistry*; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid
D002352:Carrier Proteins; D008565:Membrane Proteins