title: Implant rehabilitation in Erdheim-Chester disease: a clinical report.
abstract: Successful osseointegration of endosseous titanium implants is thought to be dependent upon close apposition of bone to the implant surface. The integration of implants in this patient was achieved despite the lipid-laden histiocytic infiltration of the bone marrow. Presumably, enough unaffected stromal cells were present to allow sufficient bone formation for osseointegration of the implant fixtures. This result invites speculation regarding both the mechanism of osseointegration and the minimum surface area of bone-implant interface necessary for achieving and maintaining osseointegration of titanium implants. This patient is periodically examined to determine if the loaded fixtures will remain clinically immobile for a prolonged period.
authors.affiliation: Clinical Investigations and Patient Care Branch, National Institutes of Health, National Institute of Dental Research, Bethesda, Md.
authors.forename: J S
authors.initials: JS
authors.lastname: Brahim
authors.forename: A D
authors.initials: AD
authors.lastname: Guckes
authors.forename: S F
authors.initials: SF
authors.lastname: Rudy
mesh_terms: D000273:Adipose Tissue; D000328:Adult; D016301:Alveolar Bone Loss / Q000534:rehabilitation / Q000601:surgery*; D001847:Bone Diseases / Q000601:surgery; D015921:Dental Implants; D006099:Granuloma; D015614:Histiocytosis; D006801:Humans; D008297:Male; D016348:Osseointegration; D013577:Syndrome
chemical_list: D015921:Dental Implants