[Influence of mast cells on the regulatory mechanisms of hemopoietic bone marrow in inflammation].
Acute infectious peritonitis simulated in mice was used to show that previous osmotic deterioration of the abdominal mast cell population significantly influenced the function of hemopoiesis-inducing microenvironment (HIM). The earlier production of the colony-stimulating and erythropoietic activities by the non-adhesive myelokaryocytes and the decreased production of these activities by the adhesive cells have been established. The results obtained evidence that mast cells modulate HIM mediating their influence on hemopoiesis under natural conditions of inflammation.
Klimenko
N A
NA
Dygaĭ
A M
AM
Gumilevskiĭ
B Iu
BIu
Bogdashin
I V
IV
Shakhov
V P
VP
Sherstoboev
E Iu
EIu
Abramova
E V
EV
Simanina
E V
EV
Gol'dberg
E D
ED
D000818:Animals; D001853:Bone Marrow / Q000503:physiopathology*; D006410:Hematopoiesis / Q000502:physiology*; D008297:Male; D008407:Mast Cells / Q000502:physiology*; D051379:Mice; D008808:Mice, Inbred CBA; D010538:Peritonitis / Q000503:physiopathology*
Vliianie tuchnykh kletok na kostnomozgovye mekhanizmy reguliatsii gemopoéza pri vospalenii.