title: Linkage disequilibrium between DPA1 and DPB1 alleles among Norwegian Caucasoids and Japanese.
abstract: Associations between alleles at the DPA1 and DPB1 loci were analyzed in 181 Norwegian caucasoids. Associations were observed between the DPA1*0201 and the DPB1*0101, *0901, *1001 and *1101 alleles. An association between DPA1*0201 and the DPB1*0901 allele was also observed among 23 healthy Japanese and 24 Japanese MS patients. In addition, it appeared that among Japanese the DPA1*0201 allele may be associated to the DPB1*0501. In conclusion, alleles at the DPA1 and DPB1 loci display different associations among Norwegian caucasoids and Japanese.
authors.affiliation: Institute of Transplantation, Immunology, National Hospital, Oslo, Norway.
authors.forename: A
authors.initials: A
authors.lastname: Spurkland
authors.forename: F
authors.initials: F
authors.lastname: Vartdal
mesh_terms: D000483:Alleles; D044466:Asian People / Q000235:genetics*; D001483:Base Sequence; D005802:Genes, MHC Class II; D006682:HLA-DP Antigens / Q000235:genetics*; D059867:HLA-DP alpha-Chains; D059868:HLA-DP beta-Chains; D006801:Humans; D007564:Japan; D015810:Linkage Disequilibrium; D008969:Molecular Sequence Data; D009103:Multiple Sclerosis / Q000235:genetics; D009664:Norway; D044465:White People / Q000235:genetics*
chemical_list: D006682:HLA-DP Antigens; D059867:HLA-DP alpha-Chains; D059868:HLA-DP beta-Chains; C071172:HLA-DPA1 antigen; C071170:HLA-DPB1 antigen