Primary amenorrhea-galactorrhea with hyperprolactinemia and huge pituitary enlargement in juvenile primary hypothyroidism.
We report a girl with juvenile primary hypothyroidism revealed by growth retardation and a syndrome of primary amenorrhea-galactorrhea with hyperprolactinemia and suprasellar pituitary enlargement. Resolution of the pituitary enlargement and the amenorrhea-galactorrhea syndrome occurred after thyroid hormone replacement. No similar observation has been reported earlier in juvenile hypothyroidism.
Chaieb
L
L
Endocrine-Metabolic Service, Farhat Hached Hospital, Sousse, Tunisia.
Chadli-Chaieb
M
M
Chaieb
A
A
Zebidi
A
A
Allegue
M
M
D000328:Adult; D000568:Amenorrhea / Q000209:etiology*; D005260:Female; D005687:Galactorrhea / Q000209:etiology*; D006130:Growth Disorders / Q000209:etiology*; D006801:Humans; D006966:Hyperprolactinemia / Q000209:etiology*; D007037:Hypothyroidism / Q000150:complications* / Q000473:pathology; D012658:Sella Turcica / Q000473:pathology*; D013577:Syndrome