Glutamate pyruvate transaminase as an indicator of infection with Plasmodium falciparum.
A correlation is shown between the presence of trophozoites and/or gametocytes of Plasmodium falciparum in thick and/or thin blood films, with the enzyme glutamate pyruvate transaminase (GPT) and a marked increase in serum GPT as a probable consequence of the presence of malaria parasite inferred. It is suggested that serum GPT levels may be used as a reliable marker for malaria infection, but only complementary to microscopic detection of falciparum malaria, rather than being specifically diagnostic.
Wurie
A T
AT
Ramsy Medical Laboratory, Freetown, Sierra Leone.
Mahdi
S O
SO
D000410:Alanine Transaminase / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D006801:Humans; D016778:Malaria, Falciparum / Q000175:diagnosis*
D015415:Biomarkers; D000410:Alanine Transaminase