Ultrastructural and immunocytochemical study of a primary gastrinoma of the liver.
A primary hepatic gastrinoma found in a 13-year-old boy was studied by light microscopy, immunohistochemistry, electron microscopy, and immunoelectron microscopy. Results were consistent with a neuroendocrine neoplasm with abundant gastrin-immunoreactive cells. Unlike all previously reported cases of primary hepatic neuroendocrine tumors, which have been endocrinologically asymptomatic, the patient had a Zollinger-Ellison syndrome apparently cured by surgical resection of the tumor.
Larriva-Sahd
J
J
Departamento de Patología, Instituto Nacional de la Nutrición SZ, México DF.
Angeles-Angeles
A
A
Hernández-Pando
R
R
Muñoz Fernández
L
L
Rondán
A
A
Orozco Estévez
H
H
Campuzano Fernández
M
M
D000293:Adolescent; D015408:Gastrinoma / Q000737:chemistry / Q000150:complications / Q000648:ultrastructure*; D005755:Gastrins / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000737:chemistry / Q000150:complications / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D015043:Zollinger-Ellison Syndrome / Q000150:complications
D005755:Gastrins