[Flow cytometric evaluation of DNA ploidy pattern in uterine cancer].
The distribution of DNA ploidy levels and its prognostic significance in cervical cancer (including squamous cell carcinoma and adenocarcinoma) and endometrial cancer is discussed. DNA aneuploidy was observed in most of the cases with either the histological type of cervical cancer and in half of those with endometrial cancer. The DNA ploidy level of the tumor showed a characteristic distribution according to its histological type or grade. Although several investigators have already reported that patients with DNA diploid uterine tumors had a better survival than those with DNA aneuploid uterine tumors, further research is required before a definite conclusion can be attained on the prognostic value of the degree of DNA ploidy measurement in uterine cancer.
Watanabe
T
T
Dept. of Obst. and Gynec. Tokyo Daini National Hosp.
Izumi
S
S
Yamaoka
K
K
Tsutsui
F
F
Nozawa
S
S
D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000473:pathology; D004273:DNA, Neoplasm / Q000032:analysis*; D016889:Endometrial Neoplasms / Q000175:diagnosis / Q000473:pathology; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D009367:Neoplasm Staging; D011003:Ploidies; D011379:Prognosis; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000473:pathology; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000473:pathology*
D004273:DNA, Neoplasm