title: Relationship between serum lipid peroxidation products in hypercholesterolemic subjects and vitamin E status.
abstract: The relationship of serum lipid peroxidation products in hypercholesterolemic subjects to their vitamin E intake was examined in 15 such subjects with no other associated significant disease process in a 3 month trial with vitamin E supplementation. These patients with elevated serum cholesterol levels also have elevated thiobarbituric acid reactive substances (TBARS) and lipid oxidation products (LOPS). Vitamin E supplementation of 800 IU daily normalized the lipid peroxidation products but did not significantly change serum lipids.
authors.affiliation: Kenneth L. Jordan Heart Fund, Montclair, New Jersey 07042.
authors.forename: M L
authors.initials: ML
authors.lastname: Bierenbaum
authors.forename: R P
authors.initials: RP
authors.lastname: Reichstein
authors.forename: H N
authors.initials: HN
authors.lastname: Bhagavan
authors.forename: T R
authors.initials: TR
authors.lastname: Watkins
mesh_terms: D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000378:metabolism; D002338:Carotenoids / Q000097:blood; D015331:Cohort Studies; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood* / Q000188:drug therapy*; D015227:Lipid Peroxidation; D008054:Lipid Peroxides / Q000097:blood*; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects; D017392:Thiobarbituric Acid Reactive Substances / Q000378:metabolism; D014810:Vitamin E / Q000097:blood / Q000627:therapeutic use*; D019207:beta Carotene
chemical_list: D000975:Antioxidants; D008054:Lipid Peroxides; D008055:Lipids; D017392:Thiobarbituric Acid Reactive Substances; D019207:beta Carotene; D014810:Vitamin E; D002338:Carotenoids