[The frequency of recurrences and metastases of bladder cancer following a radical course of radiotherapy].
The authors compare the incidence of bladder carcinoma recurrences and dissemination after long-distance gamma-beam therapy, carried out according to a traditional method, and in an accelerated hyperfractionation mode combined with metronidazole therapy. The recurrences were most frequently detected at the site of the primary tumor (62-67% of cases) in 6 to 18 months after the treatment. They come to a conclusion that accelerated hyperfractionation and local metronidazole radio-modification were conducive to a reduction of the incidence of recurrences from 45 to 28% as against the traditional split radiotherapy course in the classical fractionation mode.
Pereslegin
I A
IA
Mufazalov
F F
FF
D006801:Humans; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology*; D011879:Radiotherapy Dosage; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000532:radiotherapy*
Chastota retsidivov i metastazirovaniia raka mochevogo puzyria posle luchevoĭ terapii po radikal'noĭ programme.