Relapsing hepatitis A in Saimiri monkeys experimentally reinfected with a wild type hepatitis A virus (HAV).
Saimiri monkeys were inoculated three times with hepatitis A virus and observed in a follow-up study for sixteen months. The monkeys developed recurrent hepatitis involving liver damage and cycles of HAV antigen shedding in stools. The relapses were presumably due to immune response effects.
Prevot
S
S
Service d'Anatomie et de Cytologie Pathologiques, Hôtel Dieu, Paris, France.
Marechal
J
J
Pillot
J
J
Prevot
J
J
D000818:Animals; D005243:Feces / Q000382:microbiology; D005500:Follow-Up Studies; D014644:Genetic Variation; D006506:Hepatitis A / Q000175:diagnosis* / Q000382:microbiology; D006521:Hepatitis, Chronic / Q000175:diagnosis* / Q000473:pathology; D006524:Hepatitis, Viral, Animal / Q000175:diagnosis*; D008099:Liver / Q000473:pathology; D012008:Recurrence; D012453:Saimiri