Primary renal renin secretion responding to angiotensin converting enzyme inhibition.
A case of primary renal renin secretion of probable neoplastic origin is reported. Investigation demonstrated renin secretion to be incompletely autonomous with suboptimal suppression to posture and hypervolaemia. Easy control of the hypertension and hypokalaemia was achieved with an angiotensin converting enzyme inhibitor. Such treatment may prove to be a preferable option to surgery.
Newrick
P G
PG
Department of Medicine, Bristol Royal Infirmary, UK.
Millar
N
N
Penney
M
M
Corrall
R J
RJ
D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D007008:Hypokalemia / Q000188:drug therapy; D007668:Kidney / Q000378:metabolism*; D007680:Kidney Neoplasms / Q000378:metabolism*; D008875:Middle Aged; D012083:Renin / Q000378:metabolism*
D000806:Angiotensin-Converting Enzyme Inhibitors; D012083:Renin