title: Drug analysis of biological samples. A survey of validation approaches in chromatography in the UK pharmaceutical industry.
abstract: 1. The results of a survey on validation of analytical chromatographic methods are reported. The survey was carried out in 1990 within most of the principal British Pharmaceutical Companies. 2. A general method of validation is established from the collated results. 3. A comparison is made with existing reports from international meetings.
authors.affiliation: Bioanalytical and Pharmacokinetics Department, Sanofi Winthrop Ltd, Wythenshawe, Manchester, UK.
authors.forename: P
authors.initials: P
authors.lastname: Arnoux
authors.forename: R
authors.initials: R
authors.lastname: Morrison
mesh_terms: D002626:Chemistry, Pharmaceutical / Q000379:methods* / Q000592:standards; D002845:Chromatography / Q000379:methods; D007221:Industry / Q000379:methods*; D004364:Pharmaceutical Preparations / Q000032:analysis*; D011786:Quality Control; D015203:Reproducibility of Results; D006113:United Kingdom
chemical_list: D004364:Pharmaceutical Preparations