[A comparative study of the role of atresia and stenosis of the outflow duct of a salivary gland in the pathogenesis of dystrophic and inflammatory changes].
Experiments were carried out with submandibular salivary glands of 20 dogs. Complete obturation of the submandibular duct (in 10 animals) was achieved by binding this duct. Partial impairment of the saliva flow from the gland was induced in 10 animals by fixing a metal ring on the duct. The experiment has demonstrated that both complete and partial obturation of the salivary duct result in the development of chronic sialadenitis. Partial obturation of salivary outflow from the gland did not result in an acute inflammation but in a flaccid process, slowly developing dystrophic changes in acinar cells, gradually developing sclerosis of the glandular parenchyma and stroma. These data indicate a direct relationship between the intensity of dystrophic changes in the salivary gland and the severity of impairment of salivary discharge.
Bezrukov
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SG
D000818:Animals; D003251:Constriction, Pathologic / Q000150:complications / Q000209:etiology / Q000473:pathology; D004195:Disease Models, Animal; D004285:Dogs; D005260:Female; D008026:Ligation; D008297:Male; D012793:Sialadenitis / Q000209:etiology* / Q000473:pathology; D013363:Submandibular Gland / Q000473:pathology* / Q000601:surgery; D013364:Submandibular Gland Diseases / Q000209:etiology* / Q000473:pathology; D013997:Time Factors
Sravnitel'noe izuchenie roli atrezii i stenoza vyvodnogo protoka sliunnoĭ zhelezy v patogeneze distroficheskikh i vospalitel'nykh izmeneniĭ v neĭ.