Results of pouch surgery after ileo-anal anastomosis: the implications of pouchitis.
The ileal pouch-anal operation is the procedure of choice for those suitable patients requiring surgery for chronic ulcerative colitis or familial adenomatous polyposis. The functional results are generally good but pouchitis remains a significant and poorly understood complication. This review encompasses factors relating to pouchitis, e.g., bacteriological, functional and histological changes, with emphasis on its biology and treatment, and the long-term implications.
Fozard
B J
BJ
Department of Surgery, Mayo Clinic, Rochester, Minnesota 55905.
Pemberton
J H
JH
D001003:Anal Canal / Q000601:surgery*; D000714:Anastomosis, Surgical; D006801:Humans; D007079:Ileitis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D007082:Ileum / Q000473:pathology / Q000601:surgery*; D008679:Metaplasia; D011183:Postoperative Complications / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D015995:Prevalence; D016737:Proctocolectomy, Restorative