title: [Effect of brain cytosol proteins of embryonal and adult animals on RNA-polymerase activity of isolated brain nuclei].
abstract: Cytosol and its fractions obtained by the precipitation with ammonium sulphate and ion-exchange chromatography have been studied for their effect on the RNA-polymerase activity of isolated nuclei. We observed the discrepancies in the action of total cytosol of embryonal, newborn or adult animals on the label's incorporation in RNA. It was found that some fractions increased DNA-polymerase activity of isolated nuclei in cattle embryonal cytosol. The same fractions obtained from adult cytosol did not act in such a way. It was found that most fractions obtained from cytosol of adult brain inhibited the RNA-polymerase activity of brain nuclei.
authors.forename: A P
authors.initials: AP
authors.lastname: Ivanov
authors.forename: A A
authors.initials: AA
authors.lastname: Kapralov
authors.forename: O Ia
authors.initials: OIa
authors.lastname: Baryk
authors.forename: S V
authors.initials: SV
authors.lastname: Gubchenko
mesh_terms: D000375:Aging / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000196:embryology / Q000201:enzymology*; D002417:Cattle; D003600:Cytosol / Q000737:chemistry*; D004259:DNA-Directed DNA Polymerase / Q000378:metabolism; D012321:DNA-Directed RNA Polymerases / Q000378:metabolism*; D008099:Liver / Q000201:enzymology*; D008297:Male; D009419:Nerve Tissue Proteins / Q000502:physiology*; D009928:Organ Specificity / Q000502:physiology; D051381:Rats
chemical_list: D009419:Nerve Tissue Proteins; D012321:DNA-Directed RNA Polymerases; D004259:DNA-Directed DNA Polymerase
vernacular_title: Vliianie belkov tsitozolia mozga émbrionov i vroslykh zhivotnykh na RNK-polimeraznuiu aktivnost' izolirovannykh iader mozga.