title: Cd-metallothionein in liver and kidney of goldfish (Carassius auratus): effects of temperature and salinity.
abstract: Treatment of goldfish with Cd, by intraperitoneal injection, resulted in Cd-metallothionein (Cd-MT) synthesis mainly in liver and kidney. The relative amount of Cd sequestered by liver metallothionein was always greater in fish maintained at 20 degrees C compared to those reared at 10 degrees C, indicating a temperature dependence of metallothionein biosynthesis; in the kidney this dependence was not so clearly evident. Changes in MT levels induced by adapting fish to different salinities did not correlate with the salinity change.
authors.affiliation: Dipartimento di Biochimica, Università di Bologna.
authors.forename: E
authors.initials: E
authors.lastname: Carpené
authors.forename: A
authors.initials: A
authors.lastname: Camatti
authors.forename: G
authors.initials: G
authors.lastname: Isani
authors.forename: O
authors.initials: O
authors.lastname: Cattani
authors.forename: P
authors.initials: P
authors.lastname: Cortesi
mesh_terms: D000818:Animals; D002104:Cadmium / Q000494:pharmacology; D006054:Goldfish / Q000378:metabolism*; D007668:Kidney / Q000187:drug effects / Q000378:metabolism*; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008668:Metallothionein / Q000096:biosynthesis*; D009994:Osmolar Concentration; D012965:Sodium Chloride; D013696:Temperature
chemical_list: C004203:cadmium-binding protein; D002104:Cadmium; D012965:Sodium Chloride; D008668:Metallothionein