title: The length of the interdomain region of the L7/L12 protein is important for its function.
abstract: Several mutated L7/L12 proteins with changed interdomain regions were obtained. The results showed that the flexible region comprising the 39-52 amino acid residues is functionally important. Its length, but not its amino acid composition, is crucial for the function.
authors.affiliation: Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region.
authors.forename: M G
authors.initials: MG
authors.lastname: Bubunenko
authors.forename: S V
authors.initials: SV
authors.lastname: Chuikov
authors.forename: A T
authors.initials: AT
authors.lastname: Gudkov
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000737:chemistry / Q000378:metabolism; D004926:Escherichia coli / Q000235:genetics; D008969:Molecular Sequence Data; D016296:Mutagenesis; D010441:Peptide Chain Elongation, Translational; D011489:Protein Denaturation; D012269:Ribosomal Proteins / Q000737:chemistry / Q000378:metabolism*; D013329:Structure-Activity Relationship; D013816:Thermodynamics
chemical_list: D001426:Bacterial Proteins; D012269:Ribosomal Proteins; C016700:ribosomal protein L7-L12