[Preventive tetanus immunization and avoidance of side effects of booster immunization].
Prevalence of antibodies against tetanus toxoid (tetanus antitoxin titre) was measured in 5,235 males aged 17-60 years, 3,069 (59%) aged 20-22 years. Taking as criterion a threshold value of 0.1 IU/ml, 5,071 (97%) had adequate tetanus immunity. 1,301 of 4,355 aged 21-30 years (30%) actually had antibody concentrations above 6.3 IU/ml. Booster injections are especially contraindicated in this latter group because of the danger of side effects with further toxoid doses. Thoughtless routine booster immunization should therefore be avoided.
Schröder
J P
JP
Fachbereich Immunologie, Ernst-Rodenwaldt-Institut, Koblenz.
Kuhlmann
W D
WD
D000293:Adolescent; D000328:Adult; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007117:Immunization, Secondary / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D013742:Tetanus / Q000276:immunology / Q000517:prevention & control*; D013743:Tetanus Antitoxin / Q000032:analysis*; D013745:Tetanus Toxoid / Q000008:administration & dosage* / Q000276:immunology
D013743:Tetanus Antitoxin; D013745:Tetanus Toxoid
Tetanusimpfschutz und Vermeidung von Nebenreaktionen bei Auffrischimpfungen.