title: Synthesis and serotonergic pharmacology of the enantiomers of 3-[(N-methylpyrrolidin-2-yl)methyl]-5-methoxy-1H-indole: discovery of stereogenic differentiation in the aminoethyl side chain of the neurotransmitter serotonin.
authors.affiliation: Department of Medicinal Chemistry, Pfizer, Inc, Groton, Connecticut 06340.
authors.forename: J E
authors.initials: JE
authors.lastname: Macor
authors.forename: J
authors.initials: J
authors.lastname: Blake
authors.forename: C B
authors.initials: CB
authors.lastname: Fox
authors.forename: C
authors.initials: C
authors.lastname: Johnson
authors.forename: B K
authors.initials: BK
authors.lastname: Koe
authors.forename: L A
authors.initials: LA
authors.lastname: Lebel
authors.forename: J M
authors.initials: JM
authors.lastname: Morrone
authors.forename: K
authors.initials: K
authors.lastname: Ryan
authors.forename: A W
authors.initials: AW
authors.lastname: Schmidt
authors.forename: D W
authors.initials: DW
authors.lastname: Schulz
mesh_terms: D007211:Indoles / Q000138:chemical synthesis* / Q000494:pharmacology; D011759:Pyrrolidines / Q000138:chemical synthesis* / Q000494:pharmacology; D011985:Receptors, Serotonin / Q000187:drug effects / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism; D017366:Serotonin Receptor Agonists / Q000138:chemical synthesis* / Q000494:pharmacology; D013237:Stereoisomerism
chemical_list: D007211:Indoles; D011759:Pyrrolidines; D011985:Receptors, Serotonin; D017366:Serotonin Receptor Agonists; D012701:Serotonin