Acute alcoholic intoxication and naloxone. Effects on visual evoked potential.
Experimental assays analyzing visual evoked potential (VEP) changes during an acute alcoholic intoxication were carried out in two groups of cats: One with continuous ethanol (0.06 g/kg.min) i.v. perfusion. Another one with a naloxone (400 micrograms/kg) i.v. injection 10 min before ethylic perfusion. Naloxone potentiates alcohol effects on VEP parameters, and on the appearance of isoelectric postpotential and flat VEP.
Dawid-Milner
M S
MS
Departamento de Fisiología, Facultad de Medicina, Universidad de Navarra, Pamplona, Spain.
Díaz-Calavia
E J
EJ
Fernández del Moral
R
R
Jiménez-Vargas
J
J
D000208:Acute Disease; D000435:Alcoholic Intoxication / Q000503:physiopathology*; D000818:Animals; D002415:Cats; D005074:Evoked Potentials, Visual / Q000187:drug effects*; D008297:Male; D009270:Naloxone / Q000494:pharmacology*
D009270:Naloxone