Epidermolysis bullosa acquisita presenting with localized facial blisters.
A 44-year-old woman presented with blisters on her face of 1-month's duration. A biopsy showed a subepidermal bulla with a dermal infiltrate of inflammatory cells and thick linear deposits of immunoreactants along the dermo-epidermal junction. Using Western immunoblots, the patient's IgG antibody was found to recognize type VII procollagen. Moderate doses of oral prednisolone resulted in a complete remission, without a recurrence for more than 3 years.
Lee
C W
CW
Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea.
Jun
K M
KM
D000328:Adult; D016107:Epidermolysis Bullosa Acquisita / Q000188:drug therapy / Q000473:pathology*; D005148:Facial Dermatoses / Q000188:drug therapy / Q000473:pathology*; D005260:Female; D006801:Humans; D011239:Prednisolone / Q000627:therapeutic use; D012867:Skin / Q000473:pathology*
D011239:Prednisolone