Some aspects of structural studies on aspartic proteinases.
This paper gives a brief overview over the differences and similarities in the structure of aspartic proteinases presently available. Comparison of the three-dimentional structure of different aspartic proteinases by a common intramolecular coordinate system have been performed. The intramolecular movable subdomains have been localized and the role of motion in substrate binding and zymogen activation is discussed.
Andreeva
N S
NS
W Engelhardt Institute of Molecular Biology, Academy of Sciences of Russia, Moscow.
D000818:Animals; D016282:Aspartic Acid Endopeptidases / Q000737:chemistry*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D015394:Molecular Structure
D016282:Aspartic Acid Endopeptidases