[Immune reactions to the African swine fever virus].
Host immune reactions to African swine fever virus variants differing in their virulence were studied comparatively. Their obvious variabilities in antibody induction to some polypeptides active in antibody-dependent cell cytotoxicity and cytotoxic T-lymphocytes were demonstrated. T-helpers of immune pig splenocytes were found to recognize the cells infected with avirulent but not virulent virus variants. The described differences were not connected with the changes in SLA-1 antigen expression in the infected cells but correlated with induction of host resistance, chronic or acute course of the disease with fatal outcome.
Sereda
A D
AD
Solovkin
S L
SL
Fugina
L G
LG
Makarov
V V
VV
D000357:African Swine Fever / Q000276:immunology; D000358:African Swine Fever Virus / Q000276:immunology* / Q000472:pathogenicity; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D000920:Antibody-Dependent Cell Cytotoxicity / Q000276:immunology; D000937:Antigen-Antibody Reactions / Q000276:immunology*; D000938:Antigen-Presenting Cells / Q000276:immunology; D015941:Complement Hemolytic Activity Assay; D007114:Immunization; D013552:Swine; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology; D013997:Time Factors; D014766:Viremia / Q000276:immunology; D014774:Virulence / Q000276:immunology
D000914:Antibodies, Viral
Immunnye reaktsii na virus afrikanskoĭ chumy svineĭ.