Identification of silicone oil in the retina after intravitreal injection.
Retinal tissue obtained from 2 eyes that had been injected with silicone oil for 2 years was stained with monoclonal antibodies against macrophages and studied by light and electron microscopy and energy-dispersive x-ray analysis. Both specimens showed areas with a relatively intact architecture as well as parts with loss of normal structure. In both areas, immunostaining showed single intraretinal macrophages. Energy-dispersive x-ray results clearly demonstrated that some of the intracellular and extracellular vacuoles within the retina represented the storage sites of silicone.
Eckardt
C
C
Department of Ophthalmology, University of Kiel, Germany.
Nicolai
U
U
Czank
M
M
Schmidt
D
D
D000328:Adult; D004577:Electron Probe Microanalysis; D005260:Female; D006801:Humans; D008297:Male; D011183:Postoperative Complications; D012160:Retina / Q000737:chemistry* / Q000648:ultrastructure; D012163:Retinal Detachment / Q000601:surgery; D012827:Silicone Oils / Q000032:analysis*; D014821:Vitrectomy; D014822:Vitreous Body
D012827:Silicone Oils