title: Structure of the pericentric long arm region of the human Y chromosome.
abstract: We have analysed the sequence organization of the DNA in the pericentric region of the long arm of the human Y chromosome. The structures of one cosmid and three yeast artificial chromosome clones were determined. The region consists of a mosaic of the known 5, 48 and 68 base-pair tandemly repeated sequences and at least five novel repeated sequence families. A long range-map of approximately 3.5 x 10(6) base-pairs of genomic DNA was constructed that placed the clones between about 500 x 10(3) and 850 x 10(3) base-pairs from the long arm edge of the centromeric alphoid DNA array.
authors.affiliation: Department of Biochemistry, University of Oxford, UK.
authors.forename: K F
authors.initials: KF
authors.lastname: Cooper
authors.forename: R B
authors.initials: RB
authors.lastname: Fisher
authors.forename: C
authors.initials: C
authors.lastname: Tyler-Smith
mesh_terms: D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D002503:Centromere; D015825:Chromosomes, Fungal; D003001:Cloning, Molecular; D006224:Cricetinae; D003412:Cricetulus; D004247:DNA; D004276:DNA, Satellite / Q000032:analysis; D005260:Female; D015894:Genome, Human; D006801:Humans; D006822:Hybrid Cells; D008297:Male; D008969:Molecular Sequence Data; D012091:Repetitive Sequences, Nucleic Acid; D015183:Restriction Mapping; D014998:Y Chromosome
chemical_list: D004276:DNA, Satellite; D004247:DNA