[Fast transport of proteins in the axons of spinal cord motor neurons in rats adapted and unadapted to physical loading].
The prolonged nonintensive swimming without load (12+ +2 h) provoked a decrease of the rate of fast axonal transport in the motor fibres of the sciatic nerve by 18% and of the overall amount of transported proteins 2-fold as compared with control. The relatively short-term but more intensive activity (swimming with the load 1/11 of body weight during 60+ +10 min.) results in an increase of the rate by 10% and the overall amount of fast transported proteins 2-fold. Daily swimming (3 h. without load and 10-15 min. with load) during 20 days returns the above parametres to the controls. The compensative-adaptive changes of fast anterograde transport are the fact that may be involved in trophic communication between neuron and target cell.
Mustafin
A G
AG
Iarygin
V N
VN
D000222:Adaptation, Physiological; D000818:Animals; D001369:Axons / Q000378:metabolism*; D008297:Male; D009046:Motor Neurons / Q000378:metabolism*; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D010323:Passive Cutaneous Anaphylaxis; D051381:Rats; D013116:Spinal Cord / Q000378:metabolism*; D013550:Swimming; D013997:Time Factors
D009419:Nerve Tissue Proteins
Bystryĭ transport belkov aksonami motoneĭronov spinnogo mozga krys, predvaritel'no adaptirovannykh i neadaptirovannykh k vozdeĭstviiu fizicheskoĭ nagruzki.