title: Sinoatrial node dysfunction in recipients of domino heart transplants: complication of a surgical harvesting technique.
abstract: Two of six domino transplantations performed at our institution required permanent pacemaker implantation as a result of persistent sinoatrial node dysfunction and symptomatic nodal rhythm. Retrospective analysis of several potential etiologic factors showed that the only obvious difference between these two patients and the remaining four domino transplant recipients without this complication was the technique used during harvesting of the cardiac graft. The hearts from the two patients with sinoatrial node dysfunction were harvested using a "right atrial cuff preservation" technique, and the hearts of the remaining four patients were harvested with a standard bicaval division technique. Based on this experience, we think that this right atrial cuff preservation harvesting technique carries a potential risk for sinoatrial node damage, and we do not recommend its use for domino transplantation.
authors.affiliation: Section of Cardiovascular and Thoracic Surgery, University of Arizona, Tucson 85724.
authors.forename: L J
authors.initials: LJ
authors.lastname: Rosado
authors.forename: C L
authors.initials: CL
authors.lastname: Huston
authors.forename: G K
authors.initials: GK
authors.lastname: Sethi
authors.forename: J G
authors.initials: JG
authors.lastname: Copeland
mesh_terms: D001146:Arrhythmia, Sinus / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D006325:Heart Atria; D016027:Heart Transplantation / Q000379:methods*; D016041:Heart-Lung Transplantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial; D012189:Retrospective Studies; D012307:Risk Factors; D012849:Sinoatrial Node / Q000503:physiopathology*