title: Rhythmic activities in the rat solitary complex in vitro.
abstract: In adult rat brainstem slices, rhythmic discharge of action potentials occurred spontaneously in 10 out of 197 cells of the solitary complex. In 6 neurones, fast rhythms (2-6 per min) were characterized by volleys of synaptic activity presenting abrupt onset denoting synchronized discharge of presynaptic elements. Synchronizing signals may be generated by cells discharging bursts of high-frequency action potentials and presenting extensive axonal arborization, as observed in one cell. Slower rhythms (0.3-0.8 per min) monitored in three cells did not involve synchronizing processes and could be evoked in non-rhythmic cells by 15-30 min bath application of the cholecystokinin octapeptide (100 nM). These results suggest distinct operating mechanisms of fast and slow rhythms in the solitary complex in vitro.
authors.affiliation: Institut Alfred Fessard, CNRS, Gif-sur-Yvette, France.
authors.forename: G
authors.initials: G
authors.lastname: Fortin
authors.forename: P
authors.initials: P
authors.lastname: Branchereau
authors.forename: S
authors.initials: S
authors.lastname: Araneda
authors.forename: J
authors.initials: J
authors.lastname: Champagnat
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000818:Animals; D001369:Axons / Q000502:physiology; D001933:Brain Stem / Q000502:physiology; D004594:Electrophysiology; D066298:In Vitro Techniques; D008526:Medulla Oblongata / Q000502:physiology*; D009474:Neurons / Q000502:physiology; D051381:Rats; D012844:Sincalide / Q000494:pharmacology; D013569:Synapses / Q000502:physiology; D014630:Vagus Nerve / Q000502:physiology
chemical_list: D012844:Sincalide