title: Skeletal maturity, dental maturity, and eruption in young patients with Turner syndrome.
abstract: A major problem for patients with Turner syndrome is their small body height. The rapid biotechnologic development has now made treatment with growth hormone possible at a larger scale. The aim of this investigation was to evaluate skeletal maturity, dental maturity, and eruption in a group of young patients before hormone therapy. The material comprised 33 patients aged 7-16.7 years. The skeletal maturity, as judged from hand radiographs, was on an average 2.3 years retarded (p < 0.001) and showed increasing retardation with increasing age. The dental maturity, assessed from the formation stages of the permanent teeth on panoramic radiographs, was accelerated, with a mean value of 1 year (p < 0.001). The timing of clinical eruption did not differ significantly from that of our reference material; the Turner girls were on an average 3.7 months ahead. Several patients had local eruption problems, especially in the maxillary lateral segments. It is suggested that disharmony between tooth size and arch size may contribute to this problem.
authors.affiliation: Department of Orthodontics and Facial Orthopedics, School of Dentistry, University of Bergen, Norway.
authors.forename: M
authors.initials: M
authors.lastname: Midtbø
authors.forename: A
authors.initials: A
authors.lastname: Halse
mesh_terms: D000293:Adolescent; D000365:Age Determination by Skeleton; D000366:Age Determination by Teeth; D001846:Bone Development / Q000187:drug effects / Q000502:physiology*; D002648:Child; D004967:Estrogens / Q000627:therapeutic use; D005260:Female; D006130:Growth Disorders / Q000188:drug therapy / Q000503:physiopathology; D013006:Growth Hormone / Q000627:therapeutic use; D006801:Humans; D007621:Karyotyping; D009805:Odontogenesis / Q000187:drug effects / Q000502:physiology*; D014076:Tooth Diseases / Q000188:drug therapy / Q000503:physiopathology; D014078:Tooth Eruption / Q000187:drug effects / Q000502:physiology*; D014424:Turner Syndrome / Q000188:drug therapy / Q000235:genetics / Q000503:physiopathology*
chemical_list: D004967:Estrogens; D013006:Growth Hormone