Decreased peripheral blood eosinophil counts in severe psoriatic patients treated with low-dose cyclosporine A.
We report a clinical observation, a statistically significant decrease in peripheral blood eosinophils in patients treated with low-dose cyclosporine A for severe psoriasis 225/microliters at baseline to 114/microliters at week 12 (p = 0.04). We discuss the potential significance of this clinical finding.
Shupack
J L
JL
Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York 10016.
Kenny
C
C
Jondreau
L
L
Eckman
I
I
Gropper
C
C
Stiller
M J
MJ
D000328:Adult; D016572:Cyclosporine / Q000008:administration & dosage / Q000494:pharmacology*; D004804:Eosinophils / Q000187:drug effects*; D005260:Female; D006801:Humans; D007958:Leukocyte Count / Q000187:drug effects*; D008297:Male; D011565:Psoriasis / Q000097:blood / Q000188:drug therapy*
D016572:Cyclosporine