Stellate cells of aortic intima: I. Human and rabbit.
Stellate cells hitherto accounted exclusively in the innermost elastic-hyperplastic layer were already reported to inhabit human aortic intima. The present paper shows that most of these cells are situated just beneath the endothelium. Stellate cells also appear in the deendothelialization-induced myointimal thickening of rabbit aorta. In the myointimal thickening these cells were revealed in the direct proximity to the endothelium. A conclusion is available that the previously demonstrated polymorphism of human aortic intimal cells may be reproduced in a simple experimental model, which gives new possibilities for the study of the cellular polymorphism in the vessel wall.
Rekhter
M D
MD
Institute of Experimental Cardiology, Cardiology Res. Center, Moscow, Russia.
Andreeva
E R
ER
Andrianova
I V
IV
Mironov
A A
AA
Orekhov
A N
AN
D000328:Adult; D000818:Animals; D001011:Aorta / Q000166:cytology* / Q000648:ultrastructure; D001161:Arteriosclerosis / Q000473:pathology; D002478:Cells, Cultured; D006801:Humans; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D009131:Muscle, Smooth, Vascular / Q000166:cytology* / Q000648:ultrastructure; D011817:Rabbits; D017539:Tunica Intima / Q000166:cytology* / Q000648:ultrastructure