Morphological features of a case of retinoic acid embryopathy.
A case of retinoic acid embryopathy which was retrospectively diagnosed after delivery is presented. The affected fetus was exposed to the drug during the first month of pregnancy and second-trimester sonographic examination showed hydrocephalus and cardiac malformation. The diagnosis was made on the basis of autopsy findings and genetic enquiry.
Van Maldergem
L
L
Centre de Genetique Humaine, Institut de Morphologie Pathologique de Loverval, Belgium.
Jauniaux
E
E
Gillerot
Y
Y
D000015:Abnormalities, Multiple / Q000139:chemically induced* / Q000000981:diagnostic imaging; D000032:Abortion, Therapeutic; D000328:Adult; D005147:Facial Bones / Q000002:abnormalities; D005260:Female; D006330:Heart Defects, Congenital / Q000139:chemically induced / Q000000981:diagnostic imaging; D006801:Humans; D006849:Hydrocephalus / Q000139:chemically induced / Q000000981:diagnostic imaging; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D014212:Tretinoin / Q000009:adverse effects*; D016216:Ultrasonography, Prenatal
D014212:Tretinoin