title: Changes in pulmonary diffusing capacity and blood gases in chronic obstructive lung diseases.
abstract: Pulmonary diffusing capacity (TLco) of 19 cases of chronic obstructive lung diseases (Chronic obstructive bronchitis and chronic obstructive emphysema) in the age group of 39 to 58 years (mean age: 49.8 +/- 5.5 SD years) are reported at rest in this investigation. The diffusing capacity for carbon monoxide (TLco) measured by standard methods was significantly reduced in all cases. The mean was 13.1 +/- 2.3 SD ml/min/mmHg. The blood gas findings revealed low arterial oxygen saturation (mean value: 90.2 +/- 2.2%). Arterial carbon dioxide tension was higher than in normal subjects. The mean for this series was 44.8 +/- 4.9 SD mmHg. The mean for normal subjects was 37.5 mmHg and the range 28.2 to 41.5.
authors.affiliation: Industrial Toxicology Research Centre, Lucknow.
authors.forename: S K
authors.initials: SK
authors.lastname: Rastogi
authors.forename: S S
authors.initials: SS
authors.lastname: Lakhera
authors.forename: B
authors.initials: B
authors.lastname: Krishna
mesh_terms: D000328:Adult; D002245:Carbon Dioxide / Q000097:blood*; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood*; D011653:Pulmonary Diffusing Capacity / Q000502:physiology*
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen