title: Comparison of cytobrushes with swabs for recovery of endocervical cells and for Chlamydiazyme detection of Chlamydia trachomatis.
abstract: Endocervical swab and cytobrush specimens from 1,301 symptomatic women were microscopically analyzed for adequacy and tested using Chlamydiazyme (CZ) (Abbott Laboratories). When the swab specimen was collected first, blocking antibody-confirmed CZ-positive results were obtained from 48 (8.0%) of 599 patients, 42 (87.5%) from swabs and 46 (95.8%) from cytobrushes (not significant). When the swab specimen was collected second, confirmed CZ-positive results were obtained from 46 (6.6%) of 702 patients, 44 (95.6%) from swabs and 41 (89.1%) from cytobrushes (not significant). Cytobrushes offered no significant advantage over swabs for CZ detection of Chlamydia trachomatis.
authors.affiliation: Immunology Laboratory, York Hospital, Pennsylvania 17405.
authors.forename: J A
authors.initials: JA
authors.lastname: Kellogg
authors.forename: J W
authors.initials: JW
authors.lastname: Seiple
authors.forename: J L
authors.initials: JL
authors.lastname: Klinedinst
authors.forename: J S
authors.initials: JS
authors.lastname: Levisky
mesh_terms: D000293:Adolescent; D000328:Adult; D000942:Antigens, Bacterial / Q000302:isolation & purification; D001431:Bacteriological Techniques / Q000295:instrumentation; D002690:Chlamydia Infections / Q000175:diagnosis; D002692:Chlamydia trachomatis / Q000276:immunology / Q000302:isolation & purification*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008875:Middle Aged; D015231:Sexually Transmitted Diseases, Bacterial / Q000175:diagnosis; D014626:Vaginal Smears / Q000295:instrumentation*
chemical_list: D000942:Antigens, Bacterial