title: The prevalence of autoantibodies among right and left handed schizophrenic patients and control subjects.
abstract: Sera from schizophrenic patients (n = 186) and healthy control subjects (n = 346) were tested for the presence of seven common autoantibodies by standard immunological methods. The association between handedness and autoantibodies was tested in a multi-way contingency table using a log-linear model. For men, but not women, nondextrals (patients and controls) were twice as likely to test positive for autoantibodies than dextrals (p = 0.0002). Although more women (33%) than men (24%) tested positive for autoantibodies, handedness was not a distinguishing factor among women. These data suggest that sinistrality and gender are associated with autoantibodies in a subgroup of schizophrenic patients and healthy control subjects.
authors.affiliation: Department of Psychiatry (Immunopsychiatry Program), Western Psychiatric Institute & Clinic, University of Pittsburgh, School of Medicine, PA 15213-2593.
authors.forename: K N
authors.initials: KN
authors.lastname: Chengappa
authors.forename: R
authors.initials: R
authors.lastname: Ganguli
authors.forename: R
authors.initials: R
authors.lastname: Ulrich
authors.forename: B S
authors.initials: BS
authors.lastname: Rabin
authors.forename: J
authors.initials: J
authors.lastname: Cochran
authors.forename: J S
authors.initials: JS
authors.lastname: Brar
authors.forename: Z W
authors.initials: ZW
authors.lastname: Yang
authors.forename: M
authors.initials: M
authors.lastname: Deleo
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000032:analysis*; D001327:Autoimmune Diseases / Q000175:diagnosis / Q000276:immunology* / Q000523:psychology; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008297:Male; D012559:Schizophrenia / Q000175:diagnosis / Q000276:immunology*; D012565:Schizophrenic Psychology
chemical_list: D001323:Autoantibodies