Parasympathomimetic activity of salpantiol. A new cyclitol from Salpianthus arenarius.
A new cyclitol was isolated using the flowers of the Salpianthus arenarius, and its chemical structure was determined (2-methoxy-5hydroxymethyl cyclopentane-1,3,4-triol). The contractile effects of acetylcholine (Ach), Atropine, Pilocarpine, Adrenaline and Cyclitol were studied in rat ileum. Such cyclitol proves to have parasympathomimetic activity.
Pérez-Gutiérrez
R M
RM
Depto. de Sistemas Biológicos, Universidad Autónoma Metropolitana-Xochimilco, México D.F.
Pérez-Gutiérrez
M S
MS
D000818:Animals; D003517:Cyclopentanes / Q000737:chemistry / Q000494:pharmacology*; D066298:In Vitro Techniques; D010277:Parasympathomimetics / Q000737:chemistry / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar
D003517:Cyclopentanes; D010277:Parasympathomimetics; C077748:salpantiol