title: Cognitive outcome after cardiac operations. Relationship to intraoperative computerized electroencephalographic data.
abstract: Cardiopulmonary bypass frequently causes new postoperative neuropsychologic deficits. To assess whether these deficits could be predicted or limited, we monitored 29 patients receiving bypass intraoperatively with an on-line computerized electroencephalograph. We hypothesized that the 15 patients whose cerebral perfusion pressure was adjusted on the basis of this electroencephalographic data would have fewer postoperative deficits than the 14 patients whose pressure was monitored on the basis of systemic pressure. The results showed that new postoperative cognitive deficits in both groups were less prevalent than in previous studies, but there was not a significant difference in outcomes between the two groups. The intraoperative electroencephalographic records correlated with surgical, but not neuropsychologic, outcome. It is concluded that careful attention to intraoperative cerebral perfusion pressure may decrease the prevalence of postoperative neuropsychologic complications, but that the use of a computerized electroencephalograph does not necessarily contribute to an improved outcome.
authors.affiliation: Department of Psychology and Social Sciences, Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL 60612.
authors.forename: C L
authors.initials: CL
authors.lastname: Grote
authors.forename: P T
authors.initials: PT
authors.lastname: Shanahan
authors.forename: P
authors.initials: P
authors.lastname: Salmon
authors.forename: R G
authors.initials: RG
authors.lastname: Meyer
authors.forename: C
authors.initials: C
authors.lastname: Barrett
authors.forename: A
authors.initials: A
authors.lastname: Lansing
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002315:Cardiopulmonary Bypass / Q000009:adverse effects*; D003071:Cognition; D003201:Computers; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007427:Intracranial Pressure; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods; D011184:Postoperative Period