title: Relation between magnesium and potassium concentrations in myocardium, skeletal muscle, and mononuclear blood cells.
abstract: Potassium and magnesium were measured in 26 cardiac surgery patients (right atrial appendage), 23 autopsy subjects (right atrial appendage, left ventricular free wall, and skeletal muscle), and 9 healthy volunteers (mononuclear blood cells) to determine whether there was a relation between these two ions in the tissues measured. In the cardiac surgery patients, the potassium and magnesium concentrations were 46.35 +/- 3.89 and 4.40 +/- 0.58 (mean +/- SD, mumol/g wet weight tissue), respectively, and were significantly correlated (r = 0.54, P = 0.005). In the autopsy group, the respective concentrations were: for right atrial appendage, 30.54 +/- 10.18 and 3.66 +/- 0.70 mumol/g (r = 0.38, P = 0.14); left ventricular free wall, 60.69 +/- 17.93 and 7.74 +/- 1.73 mumol/g (r = 0.92, P = 0.0001); and skeletal muscle, 93.05 +/- 20.49 and 8.64 +/- 2.06 mumol/g (r = 0.91, P = 0.0001). In the healthy volunteer group, the results for potassium and magnesium in mononuclear blood cells were 42 +/- 9.9 and 3.99 +/- 0.70 fmol/cell, respectively (r = 0.94, P = 0.0001). Thus, potassium and magnesium concentrations were significantly correlated in all the tissues measured.
authors.affiliation: Department of Cardiology, Marshfield Clinic, WI 54449.
authors.forename: R A
authors.initials: RA
authors.lastname: Reinhart
authors.forename: S K
authors.initials: SK
authors.lastname: Broste
authors.forename: S
authors.initials: S
authors.lastname: Spencer
authors.forename: J J
authors.initials: JJ
authors.lastname: Marx
authors.forename: R G
authors.initials: RG
authors.lastname: Haas
authors.forename: P
authors.initials: P
authors.lastname: Rae
mesh_terms: D000368:Aged; D006348:Cardiac Surgical Procedures; D005260:Female; D006325:Heart Atria / Q000378:metabolism; D006352:Heart Ventricles / Q000378:metabolism; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000378:metabolism*; D008274:Magnesium / Q000097:blood / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism*; D011188:Potassium / Q000097:blood / Q000378:metabolism*
chemical_list: D008274:Magnesium; D011188:Potassium