title: Benign mesodermal tumors producing nasal deformity.
abstract: Tumors of neurogenic (ectodermal) origin are well-described causes of nasal deformity. We present a patient with a benign mesodermal tumor (unclassified spindle cell) producing nasal deformity. A retrospective review of the two senior authors' records provided an additional three patients with nonvascular benign mesodermal nasal masses (fibroma and leiomyoma). Benign mesodermal masses can occur in the midline of the nose and need to be differentiated from dermoids and gliomas. Misdiagnosis is the rule. Excisional biopsy is required for definitive diagnosis. In addition, excisional biopsy is curative and can help to minimize the subsequent nasal deformity if performed early in the disease process. Immunohistochemical and electron microscopy may be required for comprehensive diagnosis and treatment.
authors.affiliation: Division of Plastic, Reconstructive, and Maxillofacial Surgery, Northwestern University Medical School, Chicago, IL.
authors.forename: O J
authors.initials: OJ
authors.lastname: Placik
authors.forename: R
authors.initials: R
authors.lastname: Lim
authors.forename: V L
authors.initials: VL
authors.lastname: Lewis
authors.forename: B H
authors.initials: BH
authors.lastname: Griffith
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009667:Nose Deformities, Acquired / Q000209:etiology*; D009669:Nose Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D014057:Tomography, X-Ray Computed