[The role of tumor necrosis factor and interleukin-1 in forming resistance in experimental Q fever].
Preliminary injections of human recombinant tumor necrosis factor (TNF-alpha) and interleukin 1 (IL-1 beta) increases the resistance of guinea pigs to Coxiella burnetii. The increase of this resistance depends on the dose of cytokines and the time of their inoculation.
Tokarevich
N K
NK
Prokop'ev
A A
AA
Prokop'eva
E D
ED
Simbirtsev
A S
AS
Toropova
B G
BG
Daĭter
A B
AB
Ketlinskiĭ
S A
SA
D000818:Animals; D016997:Coxiella burnetii / Q000276:immunology / Q000302:isolation & purification; D004306:Dose-Response Relationship, Immunologic; D006168:Guinea Pigs; D006801:Humans; D007113:Immunity, Innate / Q000187:drug effects; D007375:Interleukin-1 / Q000276:immunology*; D011778:Q Fever / Q000276:immunology* / Q000382:microbiology; D011994:Recombinant Proteins / Q000276:immunology; D013154:Spleen / Q000276:immunology / Q000382:microbiology; D013997:Time Factors; D014409:Tumor Necrosis Factor-alpha / Q000276:immunology*
D007375:Interleukin-1; D011994:Recombinant Proteins; D014409:Tumor Necrosis Factor-alpha
Rol' faktora nekroza opukholi i interleĭkina-1 v formirovanii rezistentnosti pri éksperimental'noĭ Ku-likhorade.