Unusual bilateral renal histiocytosis. Extranodal variant of Rosai-Dorfman disease.
A 37-year-old Bangladeshi presented with large bilateral masses involving the hilus of the kidneys. No lymphadenopathy was noted. Nephrectomy was performed. Histopathologically, it revealed a lymphohistiocytic and plasma cell inflammatory tumoral proliferation with characteristic lymphophagocytosis by the S100-positive-CD1-negative histiocytes. Extranodal presentation of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) should be entertained in the differential diagnosis of bilateral masses involving the kidneys.
Afzal
M
M
Pathology Department, Central Laboratory Ministry of Health, Riyadh, Kingdom of Saudi Arabia.
Baez-Giangreco
A
A
al Jaser
A N
AN
Onuora
V C
VC
D000328:Adult; D015618:Histiocytosis, Sinus / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D007674:Kidney Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D011860:Radiography, Abdominal; D014057:Tomography, X-Ray Computed