title: Analysis of the causes of the suppression of oxidative phosphorylation and energy-dependent cationic transport into liver mitochondria of hibernating gophers, Citellus undulatus.
abstract: 1. The causes of the suppression of oxidative phosphorylation and energy-dependent cationic transport into liver mitochondria of hibernating gophers have been analysed. 2. The decrease of the ATP synthesis rate and suppression of the energy-dependent K(+)- and Ca(2+)-transport into mitochondria during hibernation has been found to be mainly related to a delta psi decrease in mitochondria of hibernating gophers. 3. The increase delta psi upon incubation of the mitochondria of hibernating animals in a hypotonic medium results in an essential acceleration of ATP synthesis and energy-dependent cationic transport.
authors.affiliation: Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Moscow Region.
authors.forename: N N
authors.initials: NN
authors.lastname: Brustovetsky
authors.forename: M V
authors.initials: MV
authors.lastname: Egorova
authors.forename: E V
authors.initials: EV
authors.lastname: Grishina
authors.forename: E I
authors.initials: EI
authors.lastname: Mayevsky
mesh_terms: D000255:Adenosine Triphosphate / Q000096:biosynthesis; D000818:Animals; D002118:Calcium / Q000378:metabolism; D004734:Energy Metabolism; D006605:Hibernation / Q000502:physiology*; D017136:Ion Transport; D008930:Mitochondria, Liver / Q000378:metabolism*; D010085:Oxidative Phosphorylation; D011188:Potassium / Q000378:metabolism; D012589:Sciuridae / Q000378:metabolism*
chemical_list: D000255:Adenosine Triphosphate; D011188:Potassium; D002118:Calcium