Coagulation screening tests in high risk neonates: a prospective cohort study.
Forty seven infants in a prospective cohort of 170 high risk neonates without signs of overt bleeding had abnormal coagulation screening tests within 36 hours of birth. Early thrombocytopenia was a better predictor of prolonged prothrombin times and hypofibrinogenemia than very low birth weight, fetal growth retardation, or poor five minute Apgar scores.
Schmidt
B K
BK
Department of Pediatrics and Pathology, McMaster University, Hamilton, Ontario, Canada.
Vegh
P
P
Andrew
M
M
Johnston
M
M
D001778:Blood Coagulation Disorders / Q000150:complications / Q000151:congenital* / Q000175:diagnosis; D001780:Blood Coagulation Tests / Q000379:methods; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D015997:Neonatal Screening / Q000379:methods*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012307:Risk Factors; D012680:Sensitivity and Specificity; D013921:Thrombocytopenia / Q000150:complications