title: Plasma lipid profile in obese children and in children with hereditary predisposition to coronary heart disease.
abstract: This study examined risk factors for coronary disease and plasma triglycerides, total cholesterol, HDL, LDL cholesterol (C), Apo A-1, and Apo B lipoprotein levels in obese children (n = 107) aged 9-12 years old and in children (n = 64) hereditarily predisposed to coronary heart disease (CHD). In the latter group, children's fathers had a history of MI before 50 years of age. A control group of 30 children was also studied, and the plasma lipid profile was investigated in 35 fathers with premature myocardial infarction. Seventy-five percent of the obese children and 60% of the children hereditarily predisposed to CHD had three or more coronary artery disease risk factors. Plasma HDL-C (p < 0.001), LDL-C (p < 0.001-p < 0.05, respectively), Apo A-1 (p < 0.001), and Apo B (p < 0.001) levels were different in both groups compared with controls.
authors.affiliation: Department of Pediatrics, Atatürk University, Research Hospital, Erzurum, Turkey.
authors.forename: F A
authors.initials: FA
authors.lastname: Paç
authors.forename: M R
authors.initials: MR
authors.lastname: Yigitoglu
authors.forename: A G
authors.initials: AG
authors.lastname: Kalayci
authors.forename: B
authors.initials: B
authors.lastname: Adam
authors.forename: S
authors.initials: S
authors.lastname: Atesal
authors.forename: M
authors.initials: M
authors.lastname: Kürkcüoglu
mesh_terms: D002648:Child; D002784:Cholesterol / Q000097:blood; D003327:Coronary Disease / Q000209:etiology / Q000235:genetics*; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D009765:Obesity / Q000097:blood*; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood
chemical_list: D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol