A preliminary observation on auto-cholinergic synapse dysfunction in patients with different types of epilepsy.
Serum anti-acetylcholine receptor antibodies (A AchR Ab) and anti-synaptic premembrane antibodies (A PrM Ab) were measured in 21 patients with absence epilepsy, 21 cases with benign childhood epilepsy with centro-temporal spikes (BCECTs) and 13 cases with atypical epilepsy. Respectively, in five (23.8%), eleven (51.2%) and eight (66.7%) of the above mentioned groups of patients both A AchR Ab and A PrM Ab were found.
Qu
Z P
ZP
WHO Collaborating Center, Shanghai Medical University, PRC.
Yu
L Y
LY
Lu
C Z
CZ
Quiao
J
J
Lin
Y X
YX
Hong
Z
Z
D000293:Adolescent; D000328:Adult; D001323:Autoantibodies / Q000097:blood*; D002648:Child; D004569:Electroencephalography; D004827:Epilepsy / Q000276:immunology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D011950:Receptors, Cholinergic / Q000276:immunology*; D013570:Synaptic Membranes / Q000276:immunology*
D001323:Autoantibodies; D011950:Receptors, Cholinergic