title: A double-blind trial of 1% ketoconazole shampoo versus placebo in the treatment of dandruff.
abstract: The efficacy of 1% ketoconazole shampoo in the treatment of dandruff was tested in a double-blind, placebo-controlled trial with 176 patients. The application of the shampoo twice weekly gave a good or excellent result in 74% of the patients treated with ketoconazole versus 20% of the patients treated with placebo after 2 weeks. After 4 weeks these results were 80% versus 23%. The shampoo was well tolerated. Only one patient in the ketoconazole group stopped treatment because of greasy hair.
authors.affiliation: Department of Dermatology, Maria Hospital, Tilburg, The Netherlands.
authors.forename: I H
authors.initials: IH
authors.lastname: Go
authors.forename: D P
authors.initials: DP
authors.lastname: Wientjens
authors.forename: M
authors.initials: M
authors.lastname: Koster
mesh_terms: D000293:Adolescent; D000328:Adult; D004311:Double-Blind Method; D006203:Hair Preparations; D006801:Humans; D007654:Ketoconazole / Q000009:adverse effects / Q000627:therapeutic use*; D012536:Scalp Dermatoses / Q000188:drug therapy*
chemical_list: D006203:Hair Preparations; D007654:Ketoconazole