[The methods for correcting with specific and nonspecific immunomodulators the immunopathological processes arising from the administration of a staphylococcal vaccine].
In mice immunized with staphylococcal vaccine the arresting of graft-versus-host reaction under the influence of small doses of staphylococcal vaccine, hyperimmune antistaphylococcal serum, cyclophosphamide, antilymphocytic serum has been demonstrated. Small doses of staphylococcal vaccine stimulated the production of antibodies to staphylococci and dermal extract in the animals, previously immunized with this vaccine, with the simultaneous suppression of cell-mediated immune reactions to both antigens. Immunosuppressing agents have been found to inhibit humoral and cell-mediated immune response to microbial antigen and dermal extract. No influence of vermox and levamisole on the outcome of the graft-versus-host reaction has been registered; the latter preparation has been found to intensify cell-mediated immune reactions to microbial and tissue antigens.
Romanov
V A
VA
Abaĭtova
N E
NE
Abd-Al-Ahad
T H
TH
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D001323:Autoantibodies / Q000097:blood; D004306:Dose-Response Relationship, Immunologic; D005260:Female; D006789:Host vs Graft Reaction / Q000187:drug effects* / Q000276:immunology; D006968:Hypersensitivity, Delayed / Q000188:drug therapy / Q000276:immunology; D007114:Immunization; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D008297:Male; D051379:Mice; D012867:Skin / Q000276:immunology; D016038:Skin Transplantation / Q000276:immunology; D013209:Staphylococcal Vaccines / Q000009:adverse effects* / Q000276:immunology; D013211:Staphylococcus aureus / Q000276:immunology; D013997:Time Factors; D014182:Transplantation, Autologous
D000276:Adjuvants, Immunologic; D000907:Antibodies, Bacterial; D001323:Autoantibodies; D007166:Immunosuppressive Agents; D013209:Staphylococcal Vaccines
Sposoby korrektsii spetsificheskimi i nespetsificheskimi immunomoduliatorami immunopatologicheskikh protsessov, voznikaiushchikh pri vvedenii stafilokokkovoĭ vaktsiny.