title: Deletional types of alpha-thalassaemia in central Java.
abstract: The frequency of deletional alpha-thalassaemia in a Javanese population sample (n = 103) was investigated at three restriction sites of the alpha-globin gene (BamHI, BglII and RsaI). The overall gene frequency of alpha+ deletional thalassaemia was found to be very low (0.03). Leftward (-alpha 4.2) and rightward (-alpha 3.7) deletions and triplicated genes were present in equal frequency (0.015 and 0.005, respectively).
authors.affiliation: Department of Paediatrics, National University of Singapore.
authors.forename: J A
authors.initials: JA
authors.lastname: Tan
authors.forename: J S
authors.initials: JS
authors.lastname: Tay
authors.forename: A
authors.initials: A
authors.lastname: Soemantri
authors.forename: S K
authors.initials: SK
authors.lastname: Kham
authors.forename: H B
authors.initials: HB
authors.lastname: Wong
authors.forename: P S
authors.initials: PS
authors.lastname: Lai
authors.forename: N
authors.initials: N
authors.lastname: Saha
mesh_terms: D000328:Adult; D005260:Female; D017353:Gene Deletion; D005838:Genotype; D005914:Globins / Q000235:genetics; D006801:Humans; D015994:Incidence; D007214:Indonesia / Q000453:epidemiology; D008297:Male; D017085:alpha-Thalassemia / Q000453:epidemiology / Q000235:genetics*
chemical_list: D005914:Globins