[The effects of dachengqi decoction, shaogan decoction, emodin and sennoside on the histamine level of intestinal mucosa in intestinally obstructed rats].
The experimental intestinal obstruction model was made by partly ligating the ileum in rat. The histamine levels of obstruction groups (8.14 +/- 2.28 micrograms/g) were obviously lower than those of control groups (P < 0.01). After administration of Dachengqi decoction, Shaogan decoction, emodin and sennoside, the levels of histamine were significantly higher than those of obstruction groups, but there were no significant differences as compared with control groups.
Lin
X
X
Tianjin Medical College.
Guo
S
S
Hou
Q
Q
Cui
R
R
Kang
Y
Y
D000818:Animals; D000880:Anthraquinones / Q000494:pharmacology; D002400:Cathartics / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use; D004642:Emodin / Q000494:pharmacology; D005260:Female; D006632:Histamine / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000378:metabolism*; D007415:Intestinal Obstruction / Q000188:drug therapy / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012676:Senna Extract; D000081226:Sennosides
D000880:Anthraquinones; D002400:Cathartics; D004365:Drugs, Chinese Herbal; D000081226:Sennosides; D012676:Senna Extract; D006632:Histamine; D004642:Emodin