title: [The effect of protease tissue inhibitor on the activity of pancreatic proteolytic enzymes in in-vitro experiments].
abstract: The authors provide the data on in vitro experimental studies into the pharmacological properties of protease inhibitor obtained from bovine pancreas. It is shown that the preparation exerts an inhibitory action on pancreatic proteolytic enzymes such as trypsin, kallikrein, and elastase, drastically reduces the total proteolytic activity in pancreatic tissue homogenates. Comparison with the protease inhibitor gordox has demonstrated the inhibitory effect of both preparations to be practically similar.
authors.forename: E F
authors.initials: EF
authors.lastname: Egorova
authors.forename: O D
authors.initials: OD
authors.lastname: Chernoiarova
authors.forename: G I
authors.initials: GI
authors.lastname: Ryzhkova
mesh_terms: D000818:Animals; D007611:Aprotinin; D002417:Cattle; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D007610:Kallikreins / Q000187:drug effects; D010179:Pancreas / Q000187:drug effects* / Q000201:enzymology; D010196:Pancreatic Elastase / Q000187:drug effects; D010447:Peptide Hydrolases / Q000187:drug effects*; D011480:Protease Inhibitors / Q000494:pharmacology*; D014357:Trypsin / Q000187:drug effects; D014361:Trypsin Inhibitors / Q000494:pharmacology
chemical_list: D011480:Protease Inhibitors; D014361:Trypsin Inhibitors; C011475:gordox; D007611:Aprotinin; D010447:Peptide Hydrolases; D007610:Kallikreins; D010196:Pancreatic Elastase; D014357:Trypsin
vernacular_title: Issledovanie vliianiia tkanevogo ingibitora proteaz na aktivnost' pankreaticheskikh proteoliticheskikh fermentov v opytakh in vitro.