[Monocyte functional activity and nonspecific antiviral cellular resistance in a group at high risk for developing acute pneumonia].
Overall 132 patients at greater risk for pneumonia were examined for functional activity of monocytes and antiviral cellular resistance according to the status of intracellular viremia in monocytes and lymphocytes. The control group included 46 healthy men. Proneness to pneumonia was discovered to be related to abnormal function of mononuclear phagocytes and a decrease of antiviral cellular resistance. The conclusion is made about the necessity of the control over functional activity of monocytes, viremia in immunocompetent cells and advisability of carrying out immunomodulatory and antiviral therapy.
Zhiburt
E B
EB
Filev
L V
LV
Povarov
Iu V
IuV
Boĭchak
M P
MP
Volchek
I V
IV
D000208:Acute Disease; D006706:Homeostasis / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D007113:Immunity, Innate; D008297:Male; D009000:Monocytes / Q000276:immunology*; D011024:Pneumonia, Viral / Q000453:epidemiology / Q000276:immunology*; D012307:Risk Factors; D014780:Viruses / Q000276:immunology*
Funktsional'naia aktivnost' monotsitov i nespetsificheskaia protivovirusnaia kletochnaia rezistentnost' v gruppe povyshennogo riska razvitiia ostroĭ pnevmonii.