title: [Radiological parameters indicating normalization of bone lesions in Langerhans-cell histiocytosis].
abstract: The signs predicting radiological healing were studied in 35 bone lesions of 12 children with Langerhans' cell histiocytosis. The earliest and more frequent radiological signs predicting healing were a decrease in size (52%), the change from a non-sclerotic lesion to one with sclerosis (41%) and the loss of distinct margins of the lesions (29%) three months after diagnosis. The first of these signs was statistically significant after three months of follow-up, the last two after 12 months. The trabecular pattern was a late (one case after 2 years) and infrequent (observed in only 24% of lesions) sign of radiological healing.
authors.affiliation: Departamento de Pediatría, Hospital General de Galicia, Santiago de Compostela.
authors.forename: J
authors.initials: J
authors.lastname: Regueiro Martínez
authors.forename: A
authors.initials: A
authors.lastname: Alonso Martín
authors.forename: P
authors.initials: P
authors.lastname: Rivas Pumar
authors.forename: M
authors.initials: M
authors.lastname: López Rivas
authors.forename: J M
authors.initials: JM
authors.lastname: Couselo Sánchez
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging; D006646:Histiocytosis, Langerhans-Cell / Q000000981:diagnostic imaging*; D006801:Humans; D007223:Infant; D008297:Male; D010014:Osteolysis / Q000000981:diagnostic imaging; D011859:Radiography; D012075:Remission, Spontaneous; D012886:Skull / Q000000981:diagnostic imaging
vernacular_title: Parámetros de normalización radiológica de las lesiones óseas de histiocitosis de células de Langerhans.