title: Clinical stage I and II endometrial carcinoma: multivariate analysis of prognostic factors.
abstract: In 221 patients with FIGO stage I and II endometrial carcinoma, the impact on survival of age at diagnosis, menopausal status, FIGO stage, myometrial invasion, tumor grade and histology was evaluated by univariate and multivariate analysis. At a median follow-up of 50 months (range 45-210), 42 patients had died, and therefore overall survival was 81% (179/221). Univariate analysis showed that age, menopausal status and histology did not influence survival, whereas FIGO stage, myometrial invasion and tumor grade were important prognostic factors. Multivariate analysis showed that tumor grade had a significant and independent impact on survival and confirmed that FIGO stage is the most important parameter influencing survival.
authors.affiliation: National Institute of Cancer Research, Genoa, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Mammoliti
authors.forename: M
authors.initials: M
authors.lastname: Bruzzone
authors.forename: S
authors.initials: S
authors.lastname: Chiara
authors.forename: A
authors.initials: A
authors.lastname: Vidali
authors.forename: L
authors.initials: L
authors.lastname: Miglio
authors.forename: V
authors.initials: V
authors.lastname: Fontana
authors.forename: C
authors.initials: C
authors.lastname: Oliva
authors.forename: E
authors.initials: E
authors.lastname: Compora
authors.forename: P
authors.initials: P
authors.lastname: Giuntini
authors.forename: M
authors.initials: M
authors.lastname: Centonze
mesh_terms: D000206:Actuarial Analysis; D016889:Endometrial Neoplasms / Q000401:mortality / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D015999:Multivariate Analysis; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011379:Prognosis; D012307:Risk Factors; D016019:Survival Analysis; D013997:Time Factors