Combined treatment of liver failure and hepatorenal syndrome with orthotopic liver transplantation.
Hepatorenal syndrome (HRS) is a severe complication of liver failure with high mortality. The pathogenesis of this reversible functional renal failure is not yet clearly understood. Diagnosis is based upon the association of clinical and biological criteria. A patient was admitted to our institution for severe liver failure secondary to an exacerbation of cirrhosis, where he developed a fulminant hepatorenal syndrome. Both, the renal and hepatic failure were successfully treated by orthotopic liver transplantation. Special attention was paid to the immunosuppressive treatment with Cyclosporine whose use, we believe, should be delayed until function has partially recovered.
Detroz
B
B
Department of Abdominal Surgery, Transplantation and Anaesthesiology, CHU-Liège, Belgium.
Honore
P
P
Monami
B
B
Meurisse
M
M
Canivet
J L
JL
Legrand
M
M
Damas
P
P
Jacquet
N
N
D006530:Hepatorenal Syndrome / Q000209:etiology / Q000601:surgery*; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000150:complications; D017114:Liver Failure, Acute / Q000601:surgery*; D008111:Liver Function Tests; D016031:Liver Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D014184:Transplantation, Homologous