title: Gluconeogenesis from methylglyoxal in isolated murine hepatocytes. Does an alternative pathway exist in which pyruvate is not an intermediate?
abstract: 1. Gluconeogenesis from alanine can be prevented by the addition of monoiodo acetic acid (an inhibitor of glyceraldehyde 3-phosphate dehydrogenase), while glucose production from methylglyoxal is only partially inhibited by this compound. 2. It is supposed that methylglyoxal can enter gluconeogenic sequence not only at pyruvate.
authors.affiliation: Semmelweis University, Medical School, First Institute of Biochemistry, Budapest, Hungary.
authors.forename: P
authors.initials: P
authors.lastname: Riba
authors.forename: T
authors.initials: T
authors.lastname: Garzó
authors.forename: J
authors.initials: J
authors.lastname: Mandl
authors.forename: M P
authors.initials: MP
authors.lastname: Kalapos
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D005943:Gluconeogenesis; D008099:Liver / Q000378:metabolism*; D051379:Mice; D011765:Pyruvaldehyde / Q000378:metabolism*; D011773:Pyruvates / Q000378:metabolism
chemical_list: D011773:Pyruvates; D011765:Pyruvaldehyde