title: Liver and serum lysosomal enzymes activity during zymosan-induced inflammation in mice.
abstract: Liver and serum lysosomal enzymes (acid glucosidases and cysteine proteinases) during zymosan-induced stimulation of MPS or MPR depression induced by GdCl3 have been studied. Zymosan was used as a model for study of inflammation in vivo. The development of inflammation induced by zymosan was followed by increase activity of macrophage activation markers - beta-N-acetylglucosaminidase (NAGlu) and beta-N-acetylgalactosaminidase (NAGal) in liver and serum. There was enhance of liver cysteine proteinases activity. Similar, less prominent (partly) data were obtained during macrophage depression induced by GdCl3.
authors.affiliation: Institute of Physiology, Academy of Medical Sciences of USSR, Novosibirsk.
authors.forename: A F
authors.initials: AF
authors.lastname: Safina
authors.forename: T A
authors.initials: TA
authors.lastname: Korolenko
authors.forename: G I
authors.initials: GI
authors.lastname: Mynkina
authors.forename: M I
authors.initials: MI
authors.lastname: Dushkin
authors.forename: G A
authors.initials: GA
authors.lastname: Krasnoselskaya
mesh_terms: D000135:Acid Phosphatase / Q000378:metabolism*; D000818:Animals; D003546:Cysteine Endopeptidases / Q000378:metabolism*; D005682:Gadolinium / Q000494:pharmacology; D006026:Glycoside Hydrolases / Q000097:blood / Q000378:metabolism*; D007249:Inflammation / Q000097:blood / Q000139:chemically induced / Q000201:enzymology*; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D008247:Lysosomes / Q000201:enzymology*; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D015054:Zymosan / Q000494:pharmacology*
chemical_list: D015054:Zymosan; D005682:Gadolinium; D000135:Acid Phosphatase; D006026:Glycoside Hydrolases; D003546:Cysteine Endopeptidases; C038958:gadolinium chloride