Identification of sialic acids in cell adhesion molecule, contact site A from Dictyostelium discoideum.
It has been believed that Dictyostelium discoideum cell membranes contain no sialic acid. In this study, however, we found that contact site A, the cell adhesion molecule of D. discoideum, is a major glycoprotein containing sialic acids. This suggests that sialic acid in non-reducing terminal plays an important role in the cell adhesion in which contact site A is involved.
Yoshida
M
M
Research Institute of Food Science, Kinki University, Osaka, Japan.
Fuse
G
G
Matsui
T
T
Ouchi
S
S
D000818:Animals; D000906:Antibodies; D001665:Binding Sites; D015815:Cell Adhesion Molecules / Q000737:chemistry* / Q000302:isolation & purification; D002462:Cell Membrane / Q000737:chemistry*; D002849:Chromatography, Gas; D004023:Dictyostelium / Q000737:chemistry*; D004591:Electrophoresis, Polyacrylamide Gel; D008401:Gas Chromatography-Mass Spectrometry; D037102:Lectins; D012794:Sialic Acids / Q000032:analysis*
D000906:Antibodies; D015815:Cell Adhesion Molecules; D037102:Lectins; D012794:Sialic Acids