title: A preliminary observation on auto-cholinergic synapse dysfunction in patients with different types of epilepsy.
abstract: Serum anti-acetylcholine receptor antibodies (A AchR Ab) and anti-synaptic premembrane antibodies (A PrM Ab) were measured in 21 patients with absence epilepsy, 21 cases with benign childhood epilepsy with centro-temporal spikes (BCECTs) and 13 cases with atypical epilepsy. Respectively, in five (23.8%), eleven (51.2%) and eight (66.7%) of the above mentioned groups of patients both A AchR Ab and A PrM Ab were found.
authors.affiliation: WHO Collaborating Center, Shanghai Medical University, PRC.
authors.forename: Z P
authors.initials: ZP
authors.lastname: Qu
authors.forename: L Y
authors.initials: LY
authors.lastname: Yu
authors.forename: C Z
authors.initials: CZ
authors.lastname: Lu
authors.forename: J
authors.initials: J
authors.lastname: Quiao
authors.forename: Y X
authors.initials: YX
authors.lastname: Lin
authors.forename: Z
authors.initials: Z
authors.lastname: Hong
mesh_terms: D000293:Adolescent; D000328:Adult; D001323:Autoantibodies / Q000097:blood*; D002648:Child; D004569:Electroencephalography; D004827:Epilepsy / Q000276:immunology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D011950:Receptors, Cholinergic / Q000276:immunology*; D013570:Synaptic Membranes / Q000276:immunology*
chemical_list: D001323:Autoantibodies; D011950:Receptors, Cholinergic