title: Encystation of Giardia lamblia leads to expression of antigens recognized by antibodies against conserved heat shock proteins.
abstract: During in vitro encystation, Giardia lamblia expresses several stage-specific proteins which are recognized in immunoblots by antisera raised against antigens from three different pathogens. The antigens belong to two different families of conserved stress proteins: (i) HSP60 purified from Legionella pneumophila and recombinant HSP60 from Mycobacterium bovis BCG and (ii) recombinant HSP70 from Plasmodium falciparum.
authors.affiliation: Department of Pathology, University of California, San Diego 92103.
authors.forename: D S
authors.initials: DS
authors.lastname: Reiner
authors.forename: T M
authors.initials: TM
authors.lastname: Shinnick
authors.forename: F
authors.initials: F
authors.lastname: Ardeshir
authors.forename: F D
authors.initials: FD
authors.lastname: Gillin
mesh_terms: D000818:Animals; D000953:Antigens, Protozoan / Q000032:analysis*; D016829:Giardia lamblia / Q000276:immunology* / Q000502:physiology; D006360:Heat-Shock Proteins / Q000276:immunology*; D007106:Immune Sera / Q000276:immunology*; D011817:Rabbits
chemical_list: D000953:Antigens, Protozoan; D006360:Heat-Shock Proteins; D007106:Immune Sera