title: Syndrome of endemic arsenism and fluorosis. A clinical study.
abstract: Sixty-five patients in Xinjiang with syndrome of endemic arsenism and fluorosis (SEAF) were investigated clinically from March 1982 to August 1989. SEAF is a kind of chronic syndrome resulting from the combined, harmful effects of two trace elements, arsenic and fluorine. Peripheral neuritis and cardiovascular changes were observed in this syndrome more often than in simple arsenism or simple fluorosis. The excessive quantities of these two trace elements in blood might have a synergic, harmful effect on the nervous and circulatory systems. No definite conclusion could be reached with regard to the morbidity of skin and visceral tumors in this series. The incidence of associated skin cancer was found to be 7.7% and an associated Grade II squamous cell carcinoma of the esophagus was encountered in one patient.
authors.affiliation: Department of Dermatology, First Affiliated Hospital, Xinjiang Medical College, Urumqi.
authors.forename: Y Z
authors.initials: YZ
authors.lastname: Huang
authors.forename: X C
authors.initials: XC
authors.lastname: Qian
authors.forename: G Q
authors.initials: GQ
authors.lastname: Wang
authors.forename: Y L
authors.initials: YL
authors.lastname: Gu
authors.forename: S Z
authors.initials: SZ
authors.lastname: Wang
authors.forename: Z H
authors.initials: ZH
authors.lastname: Cheng
authors.forename: B Y
authors.initials: BY
authors.lastname: Xiao
authors.forename: J M
authors.initials: JM
authors.lastname: Gang
authors.forename: J Y
authors.initials: JY
authors.lastname: Wu
authors.forename: M Y
authors.initials: MY
authors.lastname: Kan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D020261:Arsenic Poisoning; D002648:Child; D004244:Dizziness / Q000175:diagnosis; D005260:Female; D005458:Fluoride Poisoning / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D013577:Syndrome; D014874:Water Pollutants, Chemical / Q000009:adverse effects*; D014881:Water Supply / Q000032:analysis
chemical_list: D014874:Water Pollutants, Chemical