[Hashimoto's encephalopathy: toxic or autoimmune mechanism?].
A 36-year-old woman presented with partial complex status epilepticus. Magnetic resonance imaging with T2-weighted sequences showed a high-intensity signal in the left posterior frontal area. Hashimoto's thyroiditis was then discovered. The disappearance of the high-intensity signal after corticosteroid therapy was suggestive of an autoimmune mechanism. However, improvement could be obtained only with a hormonal treatment, which supports the hypothesis of a pathogenetic role of the Tyrosine-Releasing Hormone (TRH).
Ghawche
F
F
Service de Clinique Neurologique A, CHU, Lille.
Bordet
R
R
Destée
A
A
D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis / Q000209:etiology*; D017029:Epilepsy, Complex Partial / Q000209:etiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D013963:Thyroid Hormones / Q000097:blood; D013967:Thyroiditis, Autoimmune / Q000150:complications*; D013972:Thyrotropin / Q000097:blood
D013963:Thyroid Hormones; D013972:Thyrotropin
Encéphalopathie d'Hashimoto: toxique ou auto-immune?