title: Skin reactivity to metallic cobalt in patients with a positive patch test to cobalt chloride.
abstract: 458 consecutive patients were patch tested with a metallic cobalt disc as a supplement to the standard series. 23 patients had a positive reaction to CoCl2 1% pet. Of these, 19 were tested with the cobalt disc. 11 had a positive reaction and 5 a questionable reaction. There were no positive reactions to the cobalt disc in patients with a negative patch test to CoCl2 1% pet. Patch testing with CoCl2 1% pet. diagnoses all patients with allergy to metallic cobalt, but the test method is limited by a high number of irritant and questionable reactions.
authors.affiliation: Department of Dermatology, Gentofte Hospital, Hellerup, Denmark.
authors.forename: F
authors.initials: F
authors.lastname: de Fine Olivarius
authors.forename: T
authors.initials: T
authors.lastname: Menné
mesh_terms: D003035:Cobalt / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000209:etiology; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008297:Male; D010328:Patch Tests
chemical_list: D003035:Cobalt; C018021:cobaltous chloride