[Mathematical analysis of relations between dose, level or volume of bupivacaine and various hemodynamic parameters in epidural anesthesia].
Changes in the basic, hemodynamic parameters during the first 30 minutes of epidural anesthesia in relation of the dose, concentration, and volume of bupivacaine used are discussed. It was found, that in a proper epidural anesthesia a significant effect on the value of basic hemodynamic parameters was exerted only by a volume of administered bupivacaine solution, whereas its concentration or dose do not play any significant role. However, further prospective studies are necessary to extend this observation on the wider population.
Knapik
P
P
Zakładu Anestezjologii i Intensywnej Terapii Górniczego Centrum Medycznego, Katowicach.
Knapik
M
M
Kulej
J
J
Bończyk
A
A
Antoszewski
Z
Z
D000328:Adult; D000368:Aged; D000767:Anesthesia, Epidural; D002045:Bupivacaine / Q000008:administration & dosage* / Q000097:blood / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D005260:Female; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D013514:Surgical Procedures, Operative
D002045:Bupivacaine
Matematyczna ocena zalezności miedzy dawka, stezeniem lub objetościa bupiwakainy a niektórymi parametrami hemodynamicznymi w znieczuleniu zewnatrzoponowym.