title: [The optimization of the hypotensive therapy of hypertension patients taking into account the central hemodynamics and functional tests with obzidan and prazosin].
abstract: A study of 52 patients with hypertensive disease (grade II, age--from 30 to 50 years; men--32, women--24) using functional tests with physical loads revealed that pronounced hemodynamic changes were seen in patients with the hyperkinetic type of hemodynamics. Obsidan and prazosin reduced the degree of responses to physical loads, economy of energy expenses, increased tolerance to physical work. Association of pharmacological tests with functional physical loads in patients with hypertensive disease allows to realize selection of hypotensive drugs depending on the hemodynamic variant of the course of the pathological process and evaluate the adequacy of dosages for treatment courses.
authors.forename: I I
authors.initials: II
authors.lastname: Kryzhanovskaia
authors.forename: S S
authors.initials: SS
authors.lastname: Korolenko
authors.forename: A V
authors.initials: AV
authors.lastname: Kuriata
authors.forename: V P
authors.initials: VP
authors.lastname: Geĭchenko
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D005080:Exercise Test / Q000379:methods; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011224:Prazosin; D011433:Propranolol
chemical_list: D000959:Antihypertensive Agents; D011433:Propranolol; D011224:Prazosin
vernacular_title: Optimizatsiia gipotenzivnoĭ terapii bol'nykh gipertonicheskoĭ bolezn'iu s uchetom tsentral'noĭ gemodinamiki i funktsional'noĭ proby s ispol'zovaniem obzidana i prazozina.