title: Newcastle disease viral infection in chicken nasal turbinate and maxillary sinus.
abstract: Newcastle disease virus (NDV) B strain was inoculated intranasally and intrasinusly into unanesthetized chicken which were maintained on a standard commercial mash chicken diet until the age of 21 days after hatch. The lesions induced by NDV following intranasal inoculation usually produced a selective destruction of significant portions of the inner surface of the turbinate scroll, but sinus lesions, though sometimes present in NDV infection, were not common. The chicken sinus was infected by intrasinus inoculation. These results were supported by the amount of virus and mucociliary transport time in the turbinate and sinus. It is suggested that mucus hypersecretion of ostial gland and/or mucociliary activity in the sinus be one of the most important factors in protecting against chicken sinus infection.
authors.affiliation: Department of Otorhinolaryngology, Mie University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ukai
authors.forename: Y
authors.initials: Y
authors.lastname: Sakakura
mesh_terms: D000818:Animals; D002645:Chickens; D008443:Maxillary Sinus / Q000382:microbiology / Q000473:pathology*; D009079:Mucociliary Clearance / Q000502:physiology*; D009521:Newcastle Disease / Q000473:pathology* / Q000503:physiopathology; D009522:Newcastle disease virus / Q000302:isolation & purification; D014420:Turbinates / Q000382:microbiology / Q000473:pathology*