[Immunological profile of workers occupationally exposed to chlorine].
Immunological profile of 42 men working under exposure to chlorine for a period from 2 to 38 years was analysed. Toxicological analyses of air samples which were carried out for 20 years showed similar chlorine concentration ranging from 0.21 to 1.05 mg/m3. The number of B, T, and non-B, non-T lymphocytes was determined as well as the C3c, C4 complement components and proteins of acute phase reaction: alpha 1-acid-glycoprotein, haptoglobin and ceruloplasmin in the serum. Chronic exposure to chlorine produced a stimulating effect on the immune system, which was manifested by elevated IgA, IgD and IgM levels, the concentration of acute phase reaction proteins and increased number of B lymphocytes. The observed phenomenon had no influence on the antibacterial and anticancer immunity of the workers.
Moszczyński
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Wojewódzkiej Pracowni Immunologicznej Zespołu Opieki Zdrowotnej, Brzesku.
Słowiński
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D000328:Adult; D000395:Air Pollutants, Occupational / Q000633:toxicity*; D001402:B-Lymphocytes / Q000187:drug effects / Q000276:immunology; D002617:Chemical Industry; D002713:Chlorine / Q000633:toxicity*; D003176:Complement C3 / Q000032:analysis / Q000187:drug effects; D003181:Complement C4 / Q000032:analysis / Q000187:drug effects; D006801:Humans; D007109:Immunity / Q000187:drug effects* / Q000276:immunology; D007136:Immunoglobulins / Q000032:analysis / Q000187:drug effects; D007958:Leukocyte Count / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D011044:Poland; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D013997:Time Factors
D000395:Air Pollutants, Occupational; D003176:Complement C3; D003181:Complement C4; D007136:Immunoglobulins; D002713:Chlorine
Profil immunologiczny osób zawodowo narazonych na chlor.