title: [A case of renal cell carcinoma with lung metastasis and local recurrence effectively treated with nephrectomy and UFT].
abstract: A 74-year-old woman was admitted on July 18, 1989 for an abnormality on her chest roentgenogram. Right renal tumor with bilateral pulmonary metastasis was detected and right nephrectomy was performed. Because of the progression of pulmonary metastasis and the local recurrence after surgery, UFT was orally administered at a dose of 300 mg everyday since Dec. 12, 1989. The chest roentgenogram on Nov. 21, 1990 showed progression of lung lesions. But at the 20 th month after the beginning of chemotherapy, both lung lesions disappeared completely and local recurrence around the operative wound strikingly improved. This is a rare case of renal cell carcinoma with local recurrence and lung metastasis successfully treated with UFT.
authors.affiliation: Dept. of Respiratory Medicine, Nikko Memorial Hospital, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Taguchi
authors.forename: K
authors.initials: K
authors.lastname: Takaoka
authors.forename: M
authors.initials: M
authors.lastname: Matsuda
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D002292:Carcinoma, Renal Cell / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D008175:Lung Neoplasms / Q000556:secondary* / Q000628:therapy; D009364:Neoplasm Recurrence, Local / Q000628:therapy*; D009392:Nephrectomy; D005641:Tegafur / Q000008:administration & dosage; D014498:Uracil / Q000008:administration & dosage
chemical_list: D005641:Tegafur; D014498:Uracil