title: Sterile endophthalmitis after sutureless cataract surgery.
abstract: BACKGROUND
  Sutureless cataract surgery has recently increased in popularity because of the rapid visual rehabilitation and the inherent reduction of surgically induced astigmatism.
  
  
  METHODS
  This procedure is dependent on a lamellar, multiplaned incision. As with new surgical techniques, associated complications become evident with time. Recently, there have been several cases of infectious endophthalmitis after this procedure. The authors report on nine cases of sterile endophthalmitis. In all nine cases, surgery was performed with refrigerated balanced salt solution (BSS) and 100 mg of cefazolin and/or 20 mg of methylprednisolone sodium succinate, given subconjunctivally, at its completion.
  
  
  RESULTS
  All nine cases occurred in a period of time during which 68 cases were performed using refrigerated BSS for irrigation. These nine cases came from two different surgeons using basically the same surgical technique. After the investigation of these complications, the refrigerated BSS was discontinued, and there have been no episodes of sterile endophthalmitis in the last 650 cases.
  
  
  CONCLUSIONS
  It appears that refrigerated BSS should be avoided if periocular injections are going to be used. It may be that the cold BSS fails to allow sufficient tissue swelling to seal the surgical incision, allowing for subconjunctival injections to seep into the wound, and leading to a sterile endophthalmitis.
authors.affiliation: Department of Ophthalmology, Mercy Medical Center, Rockville Centre, New York.
authors.forename: D B
authors.initials: DB
authors.lastname: Nelson
authors.forename: E D
authors.initials: ED
authors.lastname: Donnenfeld
authors.forename: H D
authors.initials: HD
authors.lastname: Perry
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction / Q000009:adverse effects*; D003080:Cold Temperature / Q000009:adverse effects; D009877:Endophthalmitis / Q000209:etiology*; D005260:Female; D006801:Humans; D007552:Isotonic Solutions / Q000009:adverse effects; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D013536:Suture Techniques
chemical_list: D007552:Isotonic Solutions