Frequent involvement of Ig heavy chain carrier chromosome 12 in translocations in an Ehrlich-derived mouse tumor cell line.
Preferential involvement of chromosome 12, the carrier of Ig heavy chain, in structural rearrangements has been documented in an in vitro derivative of Ehrlich-Lettré mouse ascites tumor. Both copies of chromosome 12 have been found to be involved in Robertsonian and tandem translocations with certain other members of the tumor complement in this near-diploid ascites tumor cell line.
Chakrabarti
S
S
Department of Zoology, University of Burdwan, India.
Granzow
C
C
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000235:genetics*; D002881:Chromosomes, Human, Pair 12; D005803:Genes, Immunoglobulin; D006801:Humans; D007143:Immunoglobulin Heavy Chains / Q000235:genetics*; D051379:Mice; D014178:Translocation, Genetic; D014407:Tumor Cells, Cultured
D007143:Immunoglobulin Heavy Chains