title: [Evaluation of the efficacy and tolerability of nimesulide in the treatment of mastodynia].
abstract: In a double blind clinical trial 40 female patients, aged between 14 and 65 years, affected by mastodynia associated with benign non neoplastic disease of the breast, underwent oral treatment with nimesulide (200 mg/day) or placebo for a period of 15 consecutive days, during which no other drug therapy was assumed. The administration of nimesulide produced a clinically significant attenuation of mammary tenseness and mastodynia, in most cases up to complete remission of the symptoms. No adverse reaction was observed.
authors.affiliation: Ospedale di Circolo di Varese, Clinica Chirurgica, Università di Pavia.
authors.forename: R
authors.initials: R
authors.lastname: Dionigi
authors.forename: P F
authors.initials: PF
authors.lastname: Interdonato
authors.forename: I
authors.initials: I
authors.lastname: Scaricabarozzi
mesh_terms: D000293:Adolescent; D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D001941:Breast Diseases / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy*; D013449:Sulfonamides / Q000008:administration & dosage*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D013449:Sulfonamides; C012655:nimesulide
vernacular_title: Valutazione dell'efficacia e della tollerabilità della nimesulide nel trattamento della mastodinia.