Disseminated intravascular coagulation and hepatocellular necrosis due to clove oil.
We describe the case of a 2-year-old child who suffered from disseminated intravascular coagulation (DIC) and hepatocellular necrosis, following ingestion of clove oil. The patient was treated with heparin and fresh frozen plasma, and, following specific haemostasis assays, with appropriate coagulation factor and inhibitor concentrates. The case demonstrates how this approach can be successfully used in the management of DIC with coexisting liver failure.
Brown
S A
SA
Haemophilia Centre, St Thomas' Hospital, London, UK.
Biggerstaff
J
J
Savidge
G F
GF
D002675:Child, Preschool; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000139:chemically induced*; D005054:Eugenol / Q000633:toxicity*; D005340:Fibrinogen / Q000008:administration & dosage; D006493:Heparin / Q000627:therapeutic use*; D006801:Humans; D008099:Liver / Q000187:drug effects* / Q000473:pathology; D008297:Male; D009336:Necrosis / Q000139:chemically induced
D005054:Eugenol; D005340:Fibrinogen; D006493:Heparin