[Obtaining natural light photostability of drugs from lamp light exposure experiments].
The photostability of vitamin B2, vitamin K3, zinc sulfadiazine and vesnarinone, and the equivalent influences of different light sources on the photostability of the above drugs were studied under natural light and lamp lights. From this study, the photostability of drugs under different light sources can be converted to each other, and the natural light photostability of drugs can be conveniently obtained from lamp light exposure experiments. The relationship between the surface reflectance of the above drugs and the cumulative illumination of different light sources can be formulated as R = A + B(Et) + C/(Et + D) accurately, and the cumulative illumination of different light sources irradiated on the above drugs can be converted to each other equivalently.
Zhan
X C
XC
School of Pharmacy, West China University of Medical Sciences, Chengdu.
Yin
G K
GK
D004355:Drug Stability; D008027:Light; D011719:Pyrazines; D011804:Quinolines / Q000737:chemistry; D012256:Riboflavin / Q000737:chemistry; D013411:Sulfadiazine / Q000737:chemistry; D014812:Vitamin K / Q000737:chemistry
D011719:Pyrazines; D011804:Quinolines; D013411:Sulfadiazine; D014812:Vitamin K; C041667:vesnarinone; D012256:Riboflavin