Rheumatoid arthritis, corticosteroid therapy and Kaposi's sarcoma: a coincidence? A case and review of literature.
We describe a 68-year-old woman suffering from rheumatoid arthritis treated with low doses of prednisone who developed Kaposi's sarcoma (KS). This patient was not affected with AIDS, and two years previously, her sister had also complained of KS. In the literature only 8 rheumatoid arthritis patients who developed KS during steroid therapy have been reported. We present a review of the literature and question the responsibility of corticosteroids and autoimmune diseases as the cause of KS.
Casoli
P
P
2nd Department of Medicine, Ospedale S. Maria Nuova, Reggio Emilia, Italy.
Tumiati
B
B
D000305:Adrenal Cortex Hormones / Q000009:adverse effects* / Q000627:therapeutic use*; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D011241:Prednisone / Q000009:adverse effects / Q000627:therapeutic use; D012514:Sarcoma, Kaposi / Q000139:chemically induced* / Q000209:etiology*
D000305:Adrenal Cortex Hormones; D011241:Prednisone