Toxic effect of lead on fertility of inbred strain mice.
Males of inbred strains were orally given lead acetate water solution during 150 days. Changes were found in the structure of the seminiferous tubules and in spermatozoa. The pathological changes in Leydig cells brought about a decline in levels of androgens.
Godowicz
B
B
Department of Genetics and Evolution, Jagiellonian University, Kraków, Poland.
Galas
J
J
D000728:Androgens / Q000097:blood; D000818:Animals; D005298:Fertility / Q000187:drug effects*; D007854:Lead / Q000633:toxicity*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D012671:Seminiferous Tubules / Q000187:drug effects; D013076:Sperm Count; D013091:Spermatogenesis / Q000187:drug effects; D013094:Spermatozoa / Q000187:drug effects; D013737:Testis / Q000187:drug effects
D000728:Androgens; D007854:Lead