[2-Amino-3-cyano-dihydroindol-5-ones. 2. The biological activity of a new class of compounds].
2-Amino-3-cyano-dihydroindol-5-ones 2 and 3 are formed by reaction of 2-Aminopyrrole-3-carbonitriles 1 with acetylenic acid esters. In various biological test systems they behave as cytotoxic agents.
Frey
M
M
Pharmazeutisches Institut der Universität, Tübingen.
Eger
K
K
D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002478:Cells, Cultured; D006801:Humans; D007211:Indoles / Q000138:chemical synthesis* / Q000494:pharmacology
D000970:Antineoplastic Agents; D007211:Indoles
2-Amino-3-cyano-dihydroindol-5-one, 2. Mitt.: Beiträge zur biologischen Aktivität einer neuen Verbindungsklasse).