title: Routine postendarterectomy duplex surveillance: does it prevent late stroke?
abstract: Our recent finding that less than 50% of late postendarterectomy strokes are related to recurrent carotid stenosis led us to question the utility of routine postendarterectomy duplex surveillance (RpCEADS) in the prevention of late stroke. To evaluate our RpCEADS program, we reviewed our postoperative duplex studies and correlated their results with clinical data. A total of 1053 postendarterectomy scans was carried out on 348 carotid arteries (258 patients) (3.0 +/- 0.1 studies/artery) during an average follow-up of 52.6 (+/- 2.3) months. Less than 50% of recurrent carotid stenosis was documented throughout follow-up in 292 (83.9%) of 348 arteries. Recurrent carotid stenosis of greater than 50% or occlusion of either the common or internal carotid artery was noted in the remaining 56 arteries (16.1%). Of the 56 duplex-detected recurrent stenoses, only two (3.6%) resulted directly in an unheralded stroke, whereas eight (14.3%) underwent prophylactic reoperation, eight (14.3%) resulted in transient ischemia requiring reoperation, eight (14.3%) occluded without causing stroke, and 29 (51.8%) remained asymptomatic and did not progress to occlusion. Assuming that each of our eight patients who underwent prophylactic reoperation would have had a stroke if operation had not been carried out and our two unheralded strokes could have been prevented with more rigorous follow-up, RpCEADS might have prevented late stroke related to 10 (2.9%) of 348 arteries in 10 (3.9%) of 258 patients after surgery. All other cases of duplex-detected recurrent carotid stenosis or occlusion were asymptomatic or manifest by transient cerebral ischemia. Therefore RpCEADS cannot be justified as a means of preventing late strokes related to recurrent stenosis.
authors.affiliation: Department of Surgery, Tufts University School of Medicine, Boston, MA.
authors.forename: W C
authors.initials: WC
authors.lastname: Mackey
authors.forename: M
authors.initials: M
authors.lastname: Belkin
authors.forename: R
authors.initials: R
authors.lastname: Sindhi
authors.forename: H
authors.initials: H
authors.lastname: Welch
authors.forename: T F
authors.initials: TF
authors.lastname: O'Donnell
mesh_terms: D016893:Carotid Stenosis / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000601:surgery; D002561:Cerebrovascular Disorders / Q000453:epidemiology / Q000517:prevention & control*; D016894:Endarterectomy, Carotid; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care; D011183:Postoperative Complications / Q000453:epidemiology / Q000517:prevention & control; D012008:Recurrence; D012086:Reoperation; D012307:Risk Factors; D013997:Time Factors; D014463:Ultrasonography