[Plasmodium falciparum or P. malariae parasitemia in carriers of sickle cell trait in various Benin biotypes].
The prevalence of malaria and the frequency of gene S were surveyed in two different regions of Benin, savana and coastal lacustrine regions. In both regions, prevalence of malaria was not significantly different between Hb AA people and Hb AS people. Gene S prevalence was not modified by age, excepted for Hb SS which was not found in people upper than 25 years. In holoendemic area, i.e. lacustrine region, means of P. falciparum parasitaemia were significantly lower in Hb AS children than in Hb AA children. Sickle cell trait did not reduce the prevalence of malaria but seemed to decrease the level of parasitaemia.
Chippaux
J P
JP
Centre ORSTOM et Antenne OCCGE de Cotonou, Bénin.
Massougbodji
A
A
Castel
J
J
Akogbeto
M
M
Zohoun
I
I
Zohoun
T
T
D000818:Animals; D000913:Antibodies, Protozoan; D001541:Benin; D002648:Child; D002675:Child, Preschool; D004463:Ecology; D006441:Hemoglobin A / Q000235:genetics; D006451:Hemoglobin, Sickle / Q000235:genetics; D006579:Heterozygote; D006801:Humans; D007223:Infant; D008288:Malaria / Q000469:parasitology*; D016778:Malaria, Falciparum / Q000276:immunology / Q000469:parasitology*; D010641:Phenotype; D010965:Plasmodium malariae / Q000276:immunology; D011156:Population Density; D012805:Sickle Cell Trait / Q000097:blood / Q000150:complications / Q000469:parasitology*
D000913:Antibodies, Protozoan; D006451:Hemoglobin, Sickle; C028672:hemoglobin AA; C028671:hemoglobin AS; D006441:Hemoglobin A
Parasitémies à Plasmodium falciparum ou P. malariae chez les porteurs du trait drépanocytaire dans différents biotopes du Bénin.