title: Effect of antioxidants on adenosine triphosphatase activity of brain and heart in male mice during ageing.
abstract: The present study deals with the effect of butylated hydroxy anisole, propyl gallate and alpha-tocopherol on ATPase activity of brain and heart in ageing male mice. The activity of both the tissues significantly increased during pre-reproductive and reproductive phases. However, during the post-reproductive phase, ATPase activity of heart increased while that of the brain remained unaltered. The enhanced activity could be attributed to interference by the antioxidants in cellular metabolism and/or their free radical scavenging effect.
authors.affiliation: Department of Molecular Biology and Biochemistry, Guru Nanak Dev University, Amritsar, India.
authors.forename: S K
authors.initials: SK
authors.lastname: Garg
authors.forename: S C
authors.initials: SC
authors.lastname: Khanna
authors.forename: S P
authors.initials: SP
authors.lastname: Sharma
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000367:Age Factors; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001921:Brain / Q000187:drug effects* / Q000201:enzymology; D006321:Heart / Q000187:drug effects*; D008297:Male; D051379:Mice; D009206:Myocardium / Q000201:enzymology
chemical_list: D000975:Antioxidants; D000251:Adenosine Triphosphatases