[Structure and properties of the cell nucleus chromatin in the brain of rats exposed to gamma-radiation].
Exposure of rats to radiation in a dose of 1 Gy changes sensitivity of chromatin in the cerebral cortex cells to the action of DNAase 1, which promotes an increase of the DNA hydrolysis level and content of dissolved chromatin fractions. A day after irradiation the chromatin structure restores only partially and then (7-30 days after irradiation) it passes into a new, less compact state. The irradiation changes the chromatin ability to aggregation in the presence of Mg2+ and spermidine.
Chaialo
P P
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A F
AF
D000818:Animals; D002540:Cerebral Cortex / Q000737:chemistry / Q000528:radiation effects*; D002843:Chromatin / Q000737:chemistry / Q000528:radiation effects*; D004247:DNA / Q000032:analysis; D003850:Deoxyribonuclease I; D005720:Gamma Rays; D006868:Hydrolysis; D015636:Magnesium Chloride; D008297:Male; D009391:Nephelometry and Turbidimetry; D051381:Rats; D017208:Rats, Wistar; D013095:Spermidine
D002843:Chromatin; D015636:Magnesium Chloride; D004247:DNA; D003850:Deoxyribonuclease I; D013095:Spermidine
Struktura i svoĭstva khromatina iader kletok golovnogo mozga krys posle gamma-oblucheniia.