The cholesterol-raising effect of coffee in the Syrian hamster.
Adult male Syrian hamsters were fed on a high-fat diet with or without access to boiled coffee. Plasma total, low-density-lipoprotein- and high-density-lipoprotein-cholesterol and triacylglycerol concentrations were increased by the coffee and very-low-density-lipoprotein-cholesterol concentrations were lowered. It is concluded that the Syrian hamster is a suitable animal model in which to study the hypercholesterolaemic effect of coffee.
Sanders
T A
TA
Department of Nutrition and Dietetics, King's College, University of London.
Sandaradura
S
S
D000818:Animals; D003069:Coffee / Q000009:adverse effects*; D006224:Cricetinae; D004041:Dietary Fats / Q000008:administration & dosage*; D004195:Disease Models, Animal; D006937:Hypercholesterolemia / Q000139:chemically induced*; D008297:Male; D008647:Mesocricetus / Q000378:metabolism*
D003069:Coffee; D004041:Dietary Fats