title: Neutralizing antibodies against HTLV-I in HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) patients and asymptomatic carriers.
abstract: We tested serum specimens from patients with HAM/TSP and asymptomatic HTLV-I carriers from endemic areas of Japan, Jamaica, Colombia, and Chile for neutralizing antibodies against HTLV-I. The data suggest a trend for neutralizing activity to be found more frequently in the sera from HAM/TSP patients than in sera from asymptomatic carriers. The result of this study emphasizes the importance of determining biologic properties of the envelope glycoprotein of HTLV-I.
authors.affiliation: Department of Virology, Kyushu University, Fukuoka, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Minagawa
authors.forename: T
authors.initials: T
authors.lastname: Yoshida
authors.forename: Y
authors.initials: Y
authors.lastname: Itoyama
authors.forename: C A
authors.initials: CA
authors.lastname: Mora
authors.forename: P
authors.initials: P
authors.lastname: Albert
authors.forename: R
authors.initials: R
authors.lastname: Mori
mesh_terms: D002353:Carrier State / Q000276:immunology; D002460:Cell Line; D004797:Enzyme-Linked Immunosorbent Assay; D015481:HTLV-I Antibodies / Q000097:blood*; D015490:HTLV-I Infections / Q000276:immunology; D006801:Humans; D015493:Paraparesis, Tropical Spastic / Q000276:immunology*
chemical_list: D015481:HTLV-I Antibodies