title: [The characteristics of the polyclonal action and immunomodulating activity of bacterial peptidoglycans in oppositely reacting mouse strains].
abstract: The data on the specific features of the polyclonal action of gram-negative bacteria on primary immune response to sheep red blood cells in oppositely reacting mouse strains are presented. Staphylococcus aureus and Bacterium flavum peptidoglycans have been found to increase the amount of antibody producing cells to thymus-dependent antigen only in the spleen of low-responsive mice. At the same time differences in the amino acid composition of these heteropolymers do not affect their stimulating activity. Differences between the capacity of B. flavum peptidoglycans to induce the activation of B cells in mice of different strains have been established.
authors.forename: V K
authors.initials: VK
authors.lastname: Pozur
authors.forename: I A
authors.initials: IA
authors.lastname: Blium
mesh_terms: D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D000921:Antibody-Producing Cells / Q000187:drug effects / Q000276:immunology; D001951:Brevibacterium; D002473:Cell Wall / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology; D007114:Immunization; D008070:Lipopolysaccharides; D051379:Mice; D008810:Mice, Inbred C57BL / Q000276:immunology*; D008808:Mice, Inbred CBA / Q000276:immunology*; D010457:Peptidoglycan; D011550:Pseudomonas aeruginosa; D013045:Species Specificity; D013211:Staphylococcus aureus; D013329:Structure-Activity Relationship
chemical_list: D000276:Adjuvants, Immunologic; D008070:Lipopolysaccharides; D010457:Peptidoglycan
vernacular_title: Osobennosti poliklonal'nogo deĭstviia i immunomoduliruiushcheĭ aktivnosti bakterial'nykh peptidoglikanov u oppozitno reagiruiushchikh liniĭ mysheĭ.