Ultraviolet light exposure and lens opacities: the Beaver Dam Eye Study.
OBJECTIVE
Exposure to sunlight may be a risk factor for the development of cataract. The relationships between exposure to sunlight and to the ultraviolet-B (UVB) component of light and the prevalence of lens opacities were examined in the Beaver Dam Eye Study.


METHODS
Persons 43 to 84 years of age residing in Beaver Dam, Wisconsin, were examined using standardized photographic assessments of lens opacities. A questionnaire about medical history and exposure to light was administered.


RESULTS
After adjusting for other risk factors, men who had higher levels of average annual ambient UVB light were 1.36 times more likely to have more severe cortical opacities than men with lower levels. However, UVB exposure was not found to be associated with nuclear sclerosis or posterior subcapsular opacities in men. Moreover, no associations with UVB exposure were found for women, who were less likely to be exposed to UVB.


CONCLUSIONS
Exposure to UVB light may be associated with the severity of cortical opacities in men. However, the lack of an association in women, the group more likely to have cortical opacities, suggests that other factors may be more important in the pathogenesis of lens opacities.
Cruickshanks
K J
KJ
Department of Ophthalmology, University of Wisconsin, Madison.
Klein
B E
BE
Klein
R
R
D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000428:Alcohol Drinking / Q000009:adverse effects; D002386:Cataract / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D003430:Cross-Sectional Studies; D005139:Eyeglasses; D005260:Female; D006801:Humans; D007899:Leisure Activities; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011481:Protective Clothing; D012307:Risk Factors; D012621:Seasons; D012720:Severity of Illness Index; D012737:Sex Factors; D011795:Surveys and Questionnaires; D013997:Time Factors; D014466:Ultraviolet Rays / Q000009:adverse effects*; D014922:Wisconsin / Q000453:epidemiology; D014937:Work