Epidemiology of anti-HCV antibodies in France. Viral Hepatitis Study Group of the French Blood Transfusion Society.
The aim of this large survey which covered 173,038 unselected blood donors, was to determine the seroprevalence of anti-HCV antibodies and surrogate markers (ALT and anti-HBc) in France. The results revealed a frequency of 0.63% of anti-HCV positive donors. The correlation with surrogate markers was very poor but since we know nothing about the infectivity of anti-HCV negative donations, screening of surrogate markers must still be performed to prevent post-transfusional hepatitis.
Aguelles
O
O
CRTS, Vandoeuvre, France.
Janot
C
C
D000410:Alanine Transaminase / Q000097:blood; D001782:Blood Donors; D004797:Enzyme-Linked Immunosorbent Assay; D005602:France / Q000453:epidemiology; D006508:Hepatitis Antibodies / Q000097:blood*; D006511:Hepatitis B Antigens / Q000097:blood; D006526:Hepatitis C / Q000453:epidemiology / Q000517:prevention & control*; D006801:Humans; D011933:Reagent Kits, Diagnostic
D006508:Hepatitis Antibodies; D006511:Hepatitis B Antigens; D011933:Reagent Kits, Diagnostic; D000410:Alanine Transaminase