title: Analysis of complex cytogenetic alterations in three canine mammary sarcomas.
abstract: Cells of mammary sarcomas in three dogs were analysed cytogenetically. In an osteoidsarcoma, hyperdiploidy with a range of 92 to 98 chromosomes, and several structural aberrations (for example, a derivative chromosome 1, isochromosome 13 and several bi-armed markers) were observed. Isochromosome 13 was also present in a case of an osteoidchondrosarcoma. In a case of chondro-osteosarcoma both hypodiploidy with a chromosome range of 60 to 66 and hyperdiploidy with a range of 115 to 128 and several centric fusions were observed.
authors.affiliation: Institute for Animal Breeding and Genetics, Veterinary University, Vienna, Austria.
authors.forename: B
authors.initials: B
authors.lastname: Mayr
authors.forename: E
authors.initials: E
authors.lastname: Kramberger-Kaplan
authors.forename: G
authors.initials: G
authors.lastname: Loupal
authors.forename: W
authors.initials: W
authors.lastname: Schleger
mesh_terms: D000818:Animals; D002869:Chromosome Aberrations / Q000235:genetics*; D004283:Dog Diseases / Q000235:genetics* / Q000473:pathology; D004285:Dogs; D005260:Female; D007621:Karyotyping / Q000662:veterinary; D015674:Mammary Neoplasms, Animal / Q000235:genetics* / Q000473:pathology; D012516:Osteosarcoma / Q000235:genetics / Q000473:pathology / Q000662:veterinary*