Intravenous sedation for upper gastrointestinal endoscopy: Midazolam versus propofol.
Propofol was compared with Midazolam for sedation during upper gastrointestinal endoscopy in a randomised, double blind study. Both drugs were equally acceptable to endoscopists and patients. There was significant oxygen desaturation after sedation and during endoscopy (p < 10(-6)). Significantly more patients in the propofol group could remember the diagnosis which was revealed to them immediately after the gastroscopy (p < 0.001).
Chin
N M
NM
Department of Anaesthesia, Tan Tock Seng Hospital, Singapore.
Tai
H Y
HY
Chin
M K
MK
D000293:Adolescent; D000328:Adult; D000368:Aged; D000771:Anesthesia, Intravenous; D001794:Blood Pressure / Q000187:drug effects; D016292:Procedural Sedation; D003299:Cooperative Behavior; D005260:Female; D005773:Gastroscopy; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008874:Midazolam / Q000494:pharmacology; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D017060:Patient Satisfaction; D015742:Propofol / Q000494:pharmacology
D008874:Midazolam; D010100:Oxygen; D015742:Propofol