A second-generation linkage map of the human genome.
A linkage map of the human genome has been constructed based on the segregation analysis of 814 newly characterized polymorphic loci containing short tracts of (C-A)n repeats in a panel of DNAs from eight large families. Statistical linkage analysis placed 813 of the markers into 23 linkage groups corresponding to the 22 autosomes and the X chromosome; 605 show a heterozygosity above 0.7 and 553 could be ordered with odds ratios above 1,000:1. The distance spanned corresponds to approximately 90% of the estimated length of the human genome.
Weissenbach
J
J
Genethon, Evry, France.
Gyapay
G
G
Dib
C
C
Vignal
A
A
Morissette
J
J
Millasseau
P
P
Vaysseix
G
G
Lathrop
M
M
D002874:Chromosome Mapping; D002877:Chromosomes, Human; D004247:DNA / Q000235:genetics; D015723:Gene Library; D008040:Genetic Linkage; D005819:Genetic Markers; D015894:Genome, Human; D005838:Genotype; D006579:Heterozygote; D006801:Humans; D016133:Polymerase Chain Reaction; D012091:Repetitive Sequences, Nucleic Acid
D005819:Genetic Markers; D004247:DNA