title: Primary amenorrhea-galactorrhea with hyperprolactinemia and huge pituitary enlargement in juvenile primary hypothyroidism.
abstract: We report a girl with juvenile primary hypothyroidism revealed by growth retardation and a syndrome of primary amenorrhea-galactorrhea with hyperprolactinemia and suprasellar pituitary enlargement. Resolution of the pituitary enlargement and the amenorrhea-galactorrhea syndrome occurred after thyroid hormone replacement. No similar observation has been reported earlier in juvenile hypothyroidism.
authors.affiliation: Endocrine-Metabolic Service, Farhat Hached Hospital, Sousse, Tunisia.
authors.forename: L
authors.initials: L
authors.lastname: Chaieb
authors.forename: M
authors.initials: M
authors.lastname: Chadli-Chaieb
authors.forename: A
authors.initials: A
authors.lastname: Chaieb
authors.forename: A
authors.initials: A
authors.lastname: Zebidi
authors.forename: M
authors.initials: M
authors.lastname: Allegue
mesh_terms: D000328:Adult; D000568:Amenorrhea / Q000209:etiology*; D005260:Female; D005687:Galactorrhea / Q000209:etiology*; D006130:Growth Disorders / Q000209:etiology*; D006801:Humans; D006966:Hyperprolactinemia / Q000209:etiology*; D007037:Hypothyroidism / Q000150:complications* / Q000473:pathology; D012658:Sella Turcica / Q000473:pathology*; D013577:Syndrome