Initial hydrogenation during catabolism of picric acid by Rhodococcus erythropolis HL 24-2.
Rhodococcus erythropolis HL 24-2, which was originally isolated as a 2,4-dinitrophenol-degrading bacterium, could also utilize picric acid as a nitrogen source after spontaneous mutation. During growth, the mutant HL PM-1 transiently accumulated an orange-red metabolite, which was identified as a hydride-Meisenheimer complex of picric acid. This complex was formed as the initial metabolite and further converted with concomitant liberation of nitrite. 2,4,6-Trinitrocyclohexanone was identified as a dead-end metabolite of the degradation of picric acid, indicating the addition of two hydride ions to picric acid.
Lenke
H
H
Institut für Mikrobiologie, Universität Stuttgart, Germany.
Knackmuss
H J
HJ
D001673:Biodegradation, Environmental; D002208:Caproates / Q000378:metabolism; D006865:Hydrogenation; D010851:Picrates / Q000378:metabolism*; D012240:Rhodococcus / Q000254:growth & development / Q000378:metabolism*; D012988:Soil Microbiology; D014871:Water Microbiology
D002208:Caproates; D010851:Picrates; C005858:picric acid