Estimation of a common risk ratio in stratified case-cohort studies.
The case-cohort study design is a useful modification of the case-control design, which allows direct estimation of the risk ratio without the rare-disease assumption. While several risk ratio estimation procedures have been proposed under large-strata settings, only the Mantel-Haenszel point estimator is available in sparse stratifications. This paper provides simple confidence limits methods, based on the large-sample distribution of the Mantel-Haenszel risk ratio, that apply to both large-strata and sparse-data situations. For the Tarone risk ratio, I give a new large-strata variance estimate.
Sato
T
T
Institute of Statistical Mathematics, Tokyo, Japan.
D016022:Case-Control Studies; D015331:Cohort Studies; D016001:Confidence Intervals; D003627:Data Interpretation, Statistical; D006801:Humans; D015994:Incidence; D016013:Likelihood Functions; D016555:Matched-Pair Analysis; D015233:Models, Statistical; D012306:Risk