title: [The late results of observing and treating patients with histiocytosis X and involvement of the jaw bones].
abstract: Eighty-one patients with histiocytosis X involving the jaw bones were followed up for 30 years; the patients presented with involvement of the lungs, skin, mucosa, other bones of the skeleton, and diabetes insipidus signs. In 58 of the 81 patients eosinophilic granuloma eventuated in a generalized process: chronic xanthomatosis or Hand-Schüller-Christian's disease. This fact permits a conclusion that eosinophilic granuloma is an initial stage of the same systemic disease, histiocytosis X, and that subdivision of histiocytosis X into 3 forms, accepted in literature, is undesirable, for it erroneously presents the essence of the process. Therapeutic recommendations are given.
authors.forename: D Iu
authors.initials: DIu
authors.lastname: Topleninova
authors.forename: L N
authors.initials: LN
authors.lastname: Tsegel'nik
mesh_terms: D000293:Adolescent; D000328:Adult; D002908:Chronic Disease; D003131:Combined Modality Therapy; D005260:Female; D005598:Fractures, Spontaneous / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D007568:Jaw / Q000000981:diagnostic imaging; D007571:Jaw Diseases / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D008337:Mandibular Fractures / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D008875:Middle Aged; D011859:Radiography
vernacular_title: Otdalennye rezul'taty nabliudeniia i lecheniia bol'nykh gistiotsitozom X s proiavleniem v cheliustnykh kostiakh.