title: Crystallization and preliminary X-ray investigation of phosphoribosylaminoimidazolesuccinocarboxamide synthase from the yeast Saccharomyces cerevisiae.
abstract: Crystals of phosphoribosylaminoimidazolesuccinocarboxamide synthase (EC 6.3.2.6) from the yeast Saccharomyces cerevisiae were grown by the vapor diffusion hanging-drop technique, using ammonium sulfate as the precipitant. The crystals had dimensions up to 1.2 mm. X-ray diffraction experiments indicated a space group of P2(1)2(1)2(1) and unit cell parameters of a = 62.3 A, b = 63.5 A and c = 80.9 A, with one molecule in the asymmetric unit. Native data have been collected to 2.5 A resolution.
authors.affiliation: Institute of Crystallography, Academy of Sciences of Russia, Moscow.
authors.forename: A I
authors.initials: AI
authors.lastname: Grebenko
authors.forename: V M
authors.initials: VM
authors.lastname: Levdikov
authors.forename: V V
authors.initials: VV
authors.lastname: Barynin
authors.forename: W R
authors.initials: WR
authors.lastname: Melik-Adamyan
authors.forename: A N
authors.initials: AN
authors.lastname: Myasnikov
mesh_terms: D003460:Crystallization; D010453:Peptide Synthases / Q000737:chemistry*; D012441:Saccharomyces cerevisiae / Q000201:enzymology*; D014961:X-Ray Diffraction
chemical_list: D010453:Peptide Synthases; C022379:phosphoribosylaminoimidazole-succinocarboxamide synthetase