title: [An open non-comparative study of the efficacy and tolerability of sultamicillin in the therapy of respiratory infections in childhood].
abstract: Forty-eight children (25 males + 23 females), mean age 3.5 years +/- 2.6 (range 1-11), were treated for the following respiratory infections: pharyngotonsillitis (9), bronchitis (18), bronchopneumonia (14), asthmatic bronchitis (4) and pneumonia (3). The average duration of treatment was 5.3 +/- 2.0 days (range 3-13). Sultamicillin was administered at the dose of 50 mg/kg/day. Patients with fever experienced a defervescence on the second day of therapy. Forty-six children (96%) showed a good clinical response. The tolerability of the drug was excellent or good in 93.8% of the cases.
authors.affiliation: Clinica Pediatrica I, Università degli Studi di Firenze.
authors.forename: C
authors.initials: C
authors.lastname: Cocchi
authors.forename: D
authors.initials: D
authors.lastname: Seracini
authors.forename: G
authors.initials: G
authors.lastname: Bartolozzi
mesh_terms: D000367:Age Factors; D000667:Ampicillin / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination / Q000008:administration & dosage / Q000627:therapeutic use; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D013407:Sulbactam / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: C035444:sultamicillin; D000667:Ampicillin; D013407:Sulbactam
vernacular_title: Studio aperto non comparativo dell'efficacia e tollerabilità della sultamicillina nella terapia delle infezioni respiratorie in età pediatrica.