Primary malignant melanoma of the urinary bladder.
Primary malignant melanoma is an unusual neoplasm in the urinary bladder that is infrequently found in association with melanosis. We report a case of bladder-invasive malignant melanoma with melanosis in which the melanosis exhibited melanocytic atypia extending through to melanoma in situ and was diagnosed by immunohistochemical techniques using a monoclonal antibody, HMB-45. To our knowledge, such findings have not been reported previously.
Kojima
T
T
First Department of Pathology, Gifu University School of Medicine, Japan.
Tanaka
T
T
Yoshimi
N
N
Mori
H
H
D000911:Antibodies, Monoclonal; D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008544:Melanocytes / Q000473:pathology; D008545:Melanoma / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology; D008548:Melanosis / Q000473:pathology; D008875:Middle Aged; D009362:Neoplasm Metastasis; D001749:Urinary Bladder Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology
D000911:Antibodies, Monoclonal; D014408:Biomarkers, Tumor