title: Renal function in patients undergoing cardiopulmonary bypass operations.
abstract: We evaluate short- and long-term effects on renal functional reserve of cardiopulmonary bypass in 11 patients. A selected group (persistence of renal functional reserve before operation) of 11 adult patients undergoing cardiopulmonary bypass for aorta-coronary bypass were studied. Renal functional reserve tests were performed in all patients before the operation, at postoperative day 9, and at 6 months after operation. Basal glomerular filtration rate did not show significant changes at 9 days and at 6 months after operation. On the contrary, renal functional reserve was absent at 9 days, but it was restored to preoperative levels at 6 months after operation. In conclusion, our data indicate that cardiopulmonary bypass probably causes renal damage that is not sufficient to influence routine renal function parameters.
authors.affiliation: Istituto di Tipizzaazione Tissutale e problemi della dialisi-CNR di L'Aquila, Rome, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Mazzarella
authors.forename: M T
authors.initials: MT
authors.lastname: Gallucci
authors.forename: C
authors.initials: C
authors.lastname: Tozzo
authors.forename: M
authors.initials: M
authors.lastname: Elli
authors.forename: R
authors.initials: R
authors.lastname: Chiavarelli
authors.forename: B
authors.initials: B
authors.lastname: Marino
authors.forename: C
authors.initials: C
authors.lastname: Casciani
mesh_terms: D058186:Acute Kidney Injury / Q000503:physiopathology*; D000328:Adult; D002315:Cardiopulmonary Bypass / Q000009:adverse effects*; D001026:Coronary Artery Bypass; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007668:Kidney / Q000502:physiology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000503:physiopathology*