title: Unusual bilateral renal histiocytosis. Extranodal variant of Rosai-Dorfman disease.
abstract: A 37-year-old Bangladeshi presented with large bilateral masses involving the hilus of the kidneys. No lymphadenopathy was noted. Nephrectomy was performed. Histopathologically, it revealed a lymphohistiocytic and plasma cell inflammatory tumoral proliferation with characteristic lymphophagocytosis by the S100-positive-CD1-negative histiocytes. Extranodal presentation of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) should be entertained in the differential diagnosis of bilateral masses involving the kidneys.
authors.affiliation: Pathology Department, Central Laboratory Ministry of Health, Riyadh, Kingdom of Saudi Arabia.
authors.forename: M
authors.initials: M
authors.lastname: Afzal
authors.forename: A
authors.initials: A
authors.lastname: Baez-Giangreco
authors.forename: A N
authors.initials: AN
authors.lastname: al Jaser
authors.forename: V C
authors.initials: VC
authors.lastname: Onuora
mesh_terms: D000328:Adult; D015618:Histiocytosis, Sinus / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D007674:Kidney Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D011860:Radiography, Abdominal; D014057:Tomography, X-Ray Computed