title: [The problem of diffuse cranial hyperostosis following cerebral trauma in early childhood--a case report].
abstract: This is a report on an uncommon case of cranial hyperostosis with generalised considerable thickening of the calvarium. As a consequence of a cerebral trauma in early childhood the patient developed an intracerebral haematoma. Subsequently a disturbance of brain growth with posttraumatic, symptomatic epilepsy was noted. The anticonvulsant long-term treatment was mainly based on dilantin (diphenylhydantoin). Two different reasons for the distinct skull changes in the present case must be taken into consideration. Firstly, a widening of the dipole induced by dilantin, and secondly, a compensatory thickening of the vault with alterations of the skull base as seen in cerebral atrophy or after relieved hydrocephalus. These mechanisms are discussed with regard to the relevant literature.
authors.affiliation: Abteilung für Radiologie und Nuklearmedizin, Urban-Krankenhaus Berlin.
authors.forename: B
authors.initials: B
authors.lastname: Eisenschmid
authors.forename: M
authors.initials: M
authors.lastname: Friedrich
mesh_terms: D001930:Brain Injuries / Q000150:complications*; D004827:Epilepsy / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D015576:Hyperostosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010672:Phenytoin / Q000009:adverse effects
chemical_list: D010672:Phenytoin
vernacular_title: Zur Problematik der diffusen Kalottenhyperostose nach frühkindlichem Hirntrauma--Eine Kasuistik.