title: Studies on anti-Candida agents with a pyrrole moiety. Synthesis and microbiological activity of some [(1-alkyl),(1-aryl) and (1-benzyl)-5-aryl-3-carboxamido-2-methyl]pyrrole derivatives.
abstract: The synthesis of some [(1-alkyl),(1-aryl) and (1-benzyl)-5-aryl-3-carboxamido-2-methyl]pyrrole derivatives is reported. Their activity against Candida strains has been assessed and the structure-activity relationships for these compounds are discussed.
authors.affiliation: Dipartimento di Studi di Chimica e Tecnologia, Delle Sostanze Biologicamente Attive, Università La Sapienza, Roma, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Scalzo
authors.forename: M
authors.initials: M
authors.lastname: Biava
authors.forename: F
authors.initials: F
authors.lastname: Cerreto
authors.forename: A
authors.initials: A
authors.lastname: Villa
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002175:Candida / Q000187:drug effects*; D002176:Candida albicans / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011758:Pyrroles / Q000138:chemical synthesis* / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D000935:Antifungal Agents; D011758:Pyrroles