title: Apparent deficiency of metallothionein in the liver of the Antarctic icefish Chionodraco hamatus. Identification and isolation of a zinc-containing protein unlike metallothionein.
abstract: 1. A zinc-binding protein has been isolated and purified from the liver of the icefish Chionodraco hamatus. 2. The icefish Zn-protein has characteristics distinct from those of metallothionein. 3. The amino acid composition shows a low content of cysteine and a high content of glutamate and aspartate. 4. No metallothionein has been detected in the extracts from icefish liver.
authors.affiliation: CNR Institute of Protein Biochemistry and Enzymology, Napoli, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Scudiero
authors.forename: P
authors.initials: P
authors.lastname: Paolo De Prisco
authors.forename: L
authors.initials: L
authors.lastname: Camardella
authors.forename: R
authors.initials: R
authors.lastname: D'Avino
authors.forename: G
authors.initials: G
authors.lastname: di Prisco
authors.forename: E
authors.initials: E
authors.lastname: Parisi
mesh_terms: D000596:Amino Acids / Q000032:analysis; D000818:Animals; D002352:Carrier Proteins / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism; D006224:Cricetinae; D005399:Fishes / Q000378:metabolism*; D008099:Liver / Q000737:chemistry*; D008668:Metallothionein / Q000032:analysis / Q000172:deficiency; D008970:Molecular Weight; D051381:Rats; D012756:Sheep; D013045:Species Specificity; D015032:Zinc / Q000378:metabolism*
chemical_list: D000596:Amino Acids; D002352:Carrier Proteins; C017800:zinc-binding protein; D008668:Metallothionein; D015032:Zinc