title: Simultaneous measurement of left atrial pressure by Doppler echocardiography and catheterization.
abstract: Simultaneous, continuous wave Doppler echocardiography, left ventricular systolic and mean pulmonary capillary wedge pressure measurements were performed during cardiac catheterization in 54 patients with mitral regurgitation. Doppler-derived left atrial pressure, which was calculated by subtracting mitral regurgitant gradient from brachial artery systolic pressure, correlated well with mean pulmonary capillary wedge pressure by catheter (r = 0.933, SEE = 2.9 mmHg, P < 0.001); a comparison between non-invasive and invasive systolic gradients across the mitral valve yielded a high correlation (r = 0.91, SEE = 6.0 mmHg, P < 0.001); and there was also a high correlation between brachial artery and left ventricular systolic pressures (r = 0.93, SEE = 4.9 mmHg, P < 0.01). It is concluded that Doppler echocardiography provides a reliable and accurate method for complete non-invasive assessment of left atrial pressure in patients with mitral regurgitation.
authors.affiliation: Department of Cardiovascular Diseases, King Faisal Specialist Hospital and Research Centre Riyadh, Saudi Arabia.
authors.forename: Z
authors.initials: Z
authors.lastname: Ge
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.forename: D
authors.initials: D
authors.lastname: Fan
authors.forename: M
authors.initials: M
authors.lastname: Zhang
authors.forename: C M
authors.initials: CM
authors.lastname: Duran
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016279:Atrial Function, Left / Q000502:physiology*; D001783:Blood Flow Velocity / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology*; D006328:Cardiac Catheterization / Q000295:instrumentation*; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000503:physiopathology; D015150:Echocardiography, Doppler / Q000295:instrumentation*; D005260:Female; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging / Q000503:physiopathology; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000503:physiopathology; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011669:Pulmonary Wedge Pressure / Q000502:physiology*; D012214:Rheumatic Heart Disease / Q000000981:diagnostic imaging / Q000503:physiopathology