[Effect of pH on preferential antibacterial-activity of ethylenediaminetetraacetic acid (EDTA)].
Ethylenediaminetetraacetic acid (EDTA), a chelating agent, was examined for the antibacterial activity against 15 species of bacteria by treating with a 10mM solution at pH adjusted to 5.0, 7.0 or 9.0. All bacterial species tested were classified into three groups; tentatively named the pH5 EDTA-sensitive group comprising Vibrio cholerae and Staphylococcus aureus, the pH9 EDTA-sensitive group comprising Escherichia coli and Pseudomonas aeruginosa and the EDTA-nonsensitive group comprising Proteus mirabilis. The EDTA-sensitivity grouping may be used as a tool for preferential decontamination of certain bacteria in live edible fishes, although further experiments are needed to characterize more strains and also species of bacteria.
Kida
N
N
Center for Inspection of Imported Foods and Infectious Diseases, Yokohama Quarantine Station, Ministry of Health and Welfare, Kanagawa, Japan.
Suzuki
S
S
Yamanaka
T
T
Furuyama
K
K
Taguchi
F
F
D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D015169:Colony Count, Microbial; D004492:Edetic Acid / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration
D004492:Edetic Acid