title: Evolution of pericentromeric heterochromatin of human X chromosome.
abstract: An unusual large heterochromatic segment around the pericentromeric region of the X-chromosome is reported. In normal circumstances, the pericentromeric region of the X-chromosome is negative by the restriction endonuclease AluI/Giemsa technique. However, this unusual X-chromosome was found to have AluI resistant (positive) chromatin. The evolution of extra heterochromatin is a postzygotic event as substantiated by the presence of a normal cell line.
authors.affiliation: Division of Genetics, Long Island College Hospital, SUNY Health Science Center, Brooklyn 11201.
authors.forename: S
authors.initials: S
authors.lastname: Luke
authors.forename: T
authors.initials: T
authors.lastname: Mathews
authors.forename: R S
authors.initials: RS
authors.lastname: Verma
mesh_terms: D005075:Biological Evolution; D002503:Centromere; D002648:Child; D006570:Heterochromatin; D006801:Humans; D007621:Karyotyping; D008297:Male; D014960:X Chromosome
chemical_list: D006570:Heterochromatin