[Study of nuclear DNA content with flow cytometer in pancreatic diseases].
Benign and malignant diseases of the pancreas were compared with nuclear DNA content by flow cytometry, and the relationship between nuclear DNA content and histopathological findings was studied in ductal carcinoma of the pancreas. The nuclear DNA content in the malignant disease was higher than that in the benign disease. No significant correlation between nuclear DNA content and histopathological findings was observed in ductal carcinoma of the pancreas. A tendency for the nuclear DNA content to increase in proportion to the tumor size and the stage was, however, observed. Study of the nuclear DNA content is believed to be an effective adjuvant modality in differential diagnosis between benign and malignant disease of the pancreas.
Kamei
K
K
Dept. of Surgery, Fujita Health Univ., School of Med.
Funabiki
T
T
Ochiai
M
M
Marugami
Y
Y
D004247:DNA / Q000032:analysis*; D003937:Diagnosis, Differential; D005434:Flow Cytometry; D006801:Humans; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D010182:Pancreatic Diseases / Q000175:diagnosis / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000473:pathology*; D011003:Ploidies; D011379:Prognosis
D004247:DNA