Isoenzyme characterization of Leishmania braziliensis braziliensis isolates obtained from Bolivian and Peruvian patients.
Thirty-four Leishmania isolates obtained from Bolivian and Peruvian patients infected with mucocutaneous leishmaniasis were characterized by isoenzyme electrophoresis using 10 enzymatic markers; all belonged to the subspecies L.b. braziliensis. Three isolates showed marked variation compared with the reference strain with respect to 5 or 6 enzymes. These variant isolates originated from patients with forms of the disease which were unresponsive to treatment.
Revollo
S
S
Instituto Boliviano de Biología de Altura, c/o Embajada de Francia, Bolivia.
Dimier-David
L
L
David
C
C
Lyevre
P
P
Camacho
C
C
Dedet
J P
JP
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001838:Bolivia; D002648:Child; D002675:Child, Preschool; D004586:Electrophoresis; D005260:Female; D006801:Humans; D007223:Infant; D007527:Isoenzymes / Q000378:metabolism*; D007892:Leishmania braziliensis / Q000145:classification / Q000201:enzymology*; D008297:Male; D008875:Middle Aged; D010568:Peru; D013045:Species Specificity
D007527:Isoenzymes