Experimental infection of pigs with a Taenia species from Korea: parasitological and serological aspects.
Belgian Landrace piglets were experimentally infected with eggs of a Taenia sp. of Korean origin. At autopsy, metacestodes were present only in the livers. The proportion of degenerated metacestodes increased from 12%-39% at 5 weeks to 94%-100% at 10 weeks after infection. A sandwich enzyme-linked immunosorbent assay (ELISA) using monoclonal antibodies raised against the excretory-secretory products of T. saginata metacestodes detected circulating antigen in the sera of the pigs at 1 week post-infection. A good correlation was found between the presence of viable metacestodes and the detection of circulating antigen; the latter disappeared as the metacestodes died off. However, the antibodies were detected only after 3 weeks of infection and onwards until the necropsy of the pigs.
Geerts
S
S
Institute of Tropical Medicine, Antwerp, Belgium.
Zorloni
A
A
Kumar
V
V
Brandt
J R
JR
de Deken
R
R
Eom
K S
KS
D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood*; D000947:Antigens, Helminth / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D007723:Korea; D008099:Liver / Q000469:parasitology; D013552:Swine; D013621:Taenia / Q000276:immunology* / Q000302:isolation & purification; D013622:Taeniasis / Q000276:immunology / Q000469:parasitology*
D000909:Antibodies, Helminth; D000947:Antigens, Helminth