title: Association between HLA class I antigens and response to interferon therapy in children with chronic HBV hepatitis.
abstract: In this preliminary study, children with chronic HBV hepatitis, as was also previously shown for adults, respond to interferon therapy in an HLA class I antigen dependent manner. If this can be confirmed on a large scale, HLA typing may serve as a useful indication of interferon-therapy responders.
authors.affiliation: I Clinica Malattie Infettive, Università di Genova, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Giacchino
authors.forename: A
authors.initials: A
authors.lastname: Nocera
authors.forename: A
authors.initials: A
authors.lastname: Timitilli
authors.forename: E
authors.initials: E
authors.lastname: Cristina
authors.forename: G
authors.initials: G
authors.lastname: Giambartolomei
authors.forename: F
authors.initials: F
authors.lastname: Caocci
authors.forename: C
authors.initials: C
authors.lastname: Cirillo
authors.forename: S
authors.initials: S
authors.lastname: Barocci
mesh_terms: D000483:Alleles; D002648:Child; D005805:Genes, MHC Class I; D015797:HLA-B35 Antigen / Q000032:analysis*; D006509:Hepatitis B / Q000276:immunology / Q000628:therapy*; D006521:Hepatitis, Chronic / Q000276:immunology / Q000628:therapy*; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use*
chemical_list: D015797:HLA-B35 Antigen; D016898:Interferon-alpha