title: [A case of meningioma with non-accumulation of 99mTc-ECD and increased accumulation of 99mTc-HMPAO in the tumor].
abstract: 99mTc-ECD SPECT and 99mTc-HMPAO SPECT with or without Matas test were performed in a 62-year-old woman with meningioma in the left anterior cranial fossa. After injection of 740 MBq 99mTc-ECD or HMPAO, 64 projection images were collected with a rotating Gamma camera. Matas test was carried out by compressing the left common carotid artery for about one minute immediately after RI injection. Although 99mTc-ECD SPECT showed non-accumulation in the tumor, 99mTc-HMPAO SPECT demonstrated increased accumulation in it. This area of increased accumulation disappeared on 99mTc-HMPAO SPECT with Matas test which causes decrease in blood flow of the tumor. These findings suggest 99mTc-ECD and 99mTc-HMPAO have a different mechanisms of accumulation in the meningioma.
authors.affiliation: Department of Radiology, Saitama Medical Center, Saitama Medical School.
authors.forename: A
authors.initials: A
authors.lastname: Kashimada
authors.forename: K
authors.initials: K
authors.lastname: Machida
authors.forename: N
authors.initials: N
authors.lastname: Honda
authors.forename: T
authors.initials: T
authors.lastname: Mamiya
authors.forename: T
authors.initials: T
authors.lastname: Takahashi
authors.forename: T
authors.initials: T
authors.lastname: Kamano
authors.forename: M
authors.initials: M
authors.lastname: Muramatsu
authors.forename: Y
authors.initials: Y
authors.lastname: Inoue
mesh_terms: D003545:Cysteine / Q000031:analogs & derivatives*; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism; D008579:Meningioma / Q000000981:diagnostic imaging* / Q000378:metabolism; D008875:Middle Aged; D015609:Organotechnetium Compounds / Q000493:pharmacokinetics; D010091:Oximes / Q000493:pharmacokinetics; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; C059659:technetium Tc 99m bicisate; D003545:Cysteine