Neuroleptic malignant syndrome in a patient with neurosyphilis.
Neuroleptic malignant syndrome (NMS) is a catatonic-like syndrome of uncertain etiology occurring in patients taking dopamine blocking medications. The paper describes how NMS presents and is treated and reports the case of a patient with undetected neurosyphilis who developed NMS. The case highlights the need for a thorough organic evaluation of all patients with initial-onset psychotic features and suggests the possibility of a CNS cofactor--neurosyphilis--initiating the NMS as proposed by other researchers.
Cannon
T
T
Medical College of Wisconsin.
Sperry
L
L
D000328:Adult; D006801:Humans; D008297:Male; D009459:Neuroleptic Malignant Syndrome / Q000150:complications* / Q000175:diagnosis; D009494:Neurosyphilis / Q000150:complications* / Q000175:diagnosis