title: Eosinophils as host cells for HIV-1.
abstract: Transient expression of HIV-1 p24 antigen was observed in eosinophils acutely infected with the HTLV-IIIB strain of HIV-1. PCR analysis of eosinophils isolated from 18 seropositive individuals showed HIV-1 sequences to be present in 2 subjects. These data suggest that eosinophils may act as host cells for HIV-1.
authors.affiliation: Infectious Diseases Unit, Massachusetts General Hospital, Boston.
authors.forename: B
authors.initials: B
authors.lastname: Conway
authors.forename: P
authors.initials: P
authors.lastname: Baskar
authors.forename: L J
authors.initials: LJ
authors.lastname: Bechtel
authors.forename: J C
authors.initials: JC
authors.lastname: Kaplan
authors.forename: M S
authors.initials: MS
authors.lastname: Hirsch
authors.forename: R T
authors.initials: RT
authors.lastname: Schooley
authors.forename: S H
authors.initials: SH
authors.lastname: Pincus
mesh_terms: D004279:DNA, Viral / Q000032:analysis; D004804:Eosinophils / Q000382:microbiology*; D015488:HIV Antigens / Q000032:analysis; D016655:HIV Core Protein p24 / Q000378:metabolism; D015658:HIV Infections / Q000097:blood*; D015497:HIV-1 / Q000254:growth & development* / Q000276:immunology; D006801:Humans; D016133:Polymerase Chain Reaction; D014779:Virus Replication
chemical_list: D004279:DNA, Viral; D015488:HIV Antigens; D016655:HIV Core Protein p24