title: [Antibody detection in zoonotic cutaneous leishmaniasis by using the indirect immunofluorescence reaction and C-ELISA in different clinical manifestations of the disease].
abstract: 189 sera from patients with ZCL of different stages were studied by means of RNIF and C-ELISA. A high significant correlation between RNIF and C-ELISA indices was shown, but the latter test was proved to be more sensitive and therefore more effective. In patients with ZCL, a significant direct correlation between the duration of the process and the antibody titer was established by means of C-ELISA. In patients with ZCL at the third (final) stage (reduction and granulation of lesions), the C-ELISA liter of specific antibodies was higher than at the second stage (rapidly progressing ulceration of lesions). The findings indicate the presence of clinical and serological parallels in ZCL and show it expedient to compare the dynamics of antibody genesis and cell immunity indices in further studies.
authors.forename: Kh Kh
authors.initials: KhKh
authors.lastname: Khuseĭinova
authors.forename: R S
authors.initials: RS
authors.lastname: Dobrzhanskaia
authors.forename: V M
authors.initials: VM
authors.lastname: Saf'ianova
authors.forename: L I
authors.initials: LI
authors.lastname: Gracheva
authors.forename: D B
authors.initials: DB
authors.lastname: Goncharov
authors.forename: I V
authors.initials: IV
authors.lastname: Khanafieva
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D016009:Chi-Square Distribution; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods* / Q000706:statistics & numerical data; D005260:Female; D005455:Fluorescent Antibody Technique / Q000706:statistics & numerical data; D006801:Humans; D007895:Leishmania tropica / Q000276:immunology*; D016773:Leishmaniasis, Cutaneous / Q000175:diagnosis* / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results
chemical_list: D000913:Antibodies, Protozoan
vernacular_title: Vyiavlenie antitel pri zoonoznom kozhnom leĭshmanioze s pomoshch'iu RNIF i C-ELISA pri razlichnykh klinicheskikh proiavleniiakh bolezni.