title: [Hashimoto's encephalopathy: toxic or autoimmune mechanism?].
abstract: A 36-year-old woman presented with partial complex status epilepticus. Magnetic resonance imaging with T2-weighted sequences showed a high-intensity signal in the left posterior frontal area. Hashimoto's thyroiditis was then discovered. The disappearance of the high-intensity signal after corticosteroid therapy was suggestive of an autoimmune mechanism. However, improvement could be obtained only with a hormonal treatment, which supports the hypothesis of a pathogenetic role of the Tyrosine-Releasing Hormone (TRH).
authors.affiliation: Service de Clinique Neurologique A, CHU, Lille.
authors.forename: F
authors.initials: F
authors.lastname: Ghawche
authors.forename: R
authors.initials: R
authors.lastname: Bordet
authors.forename: A
authors.initials: A
authors.lastname: Destée
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis / Q000209:etiology*; D017029:Epilepsy, Complex Partial / Q000209:etiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D013963:Thyroid Hormones / Q000097:blood; D013967:Thyroiditis, Autoimmune / Q000150:complications*; D013972:Thyrotropin / Q000097:blood
chemical_list: D013963:Thyroid Hormones; D013972:Thyrotropin
vernacular_title: Encéphalopathie d'Hashimoto: toxique ou auto-immune?