Eosinophil-mediated bile duct stricture. A case studied by immunohistochemistry.
Major basic protein accounts for the majority of the protein within the eosinophilic granule. Utilizing immunohistochemical staining for major basic protein, we have demonstrated the dominant role of the eosinophil in a reversible bile duct stricture.
Schlinkert
R T
RT
Department of Surgery, Mayo Clinic Scottsdale, AZ 85259.
de la Garza-Grahm
M
M
Reeder
C B
CB
Weiland
L H
LH
Beart
R W
RW
Gleich
G J
GJ
Kephart
G M
GM
de Groen
P C
PC
D001798:Blood Proteins / Q000032:analysis; D002779:Cholestasis / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D047091:Eosinophil Granule Proteins; D004802:Eosinophilia / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D012260:Ribonucleases; D014364:Tryptophan / Q000009:adverse effects
D001798:Blood Proteins; D047091:Eosinophil Granule Proteins; D014364:Tryptophan; D012260:Ribonucleases