Crosstalk among multiple signal-activated phospholipases.
Transduction of extracellular signals across the plasma membrane often involves activation of several phospholipases that generate multiple, sometimes interconvertible, lipid-derived messengers. Coordination and integration of these signal-activated phospholipases may require crosstalk between both the messengers and target protein constituents of these pathways.
Liscovitch
M
M
Department of Hormone Research, Weizmann Institute of Science, Rehovot, Israel.
D000818:Animals; D002118:Calcium / Q000502:physiology; D004789:Enzyme Activation / Q000502:physiology; D006801:Humans; D010740:Phospholipases / Q000378:metabolism*; D010743:Phospholipids / Q000378:metabolism; D011493:Protein Kinase C / Q000502:physiology; D015290:Second Messenger Systems / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology*
D010743:Phospholipids; D011493:Protein Kinase C; D010740:Phospholipases; D002118:Calcium