title: Effect of prednisone priming followed by alfa-interferon in treatment of children with chronic hepatitis B: an interim analysis of a controlled trial.
abstract: A six-month analysis of a controlled trial on the treatment of chronic hepatitis B in children shows that prednisone priming followed by alpha-interferon 2A was effective in 6 of 9 treated patients in reducing HBV replication and disease activity.
authors.affiliation: Clinic of Infectious Diseases and Tropical/Subtropical Diseases, 1st Medical School University of Naples, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Utili
authors.forename: E
authors.initials: E
authors.lastname: Sagnelli
authors.forename: G
authors.initials: G
authors.lastname: Giusti
authors.forename: G
authors.initials: G
authors.lastname: Ruggiero
authors.forename: F
authors.initials: F
authors.lastname: Piccinino
authors.forename: B
authors.initials: B
authors.lastname: Galanti
authors.forename: L E
authors.initials: LE
authors.lastname: Adinolfi
authors.forename: L
authors.initials: L
authors.lastname: Aprea
authors.forename: G
authors.initials: G
authors.lastname: Cesaro
authors.forename: L
authors.initials: L
authors.lastname: Digilio
mesh_terms: D000293:Adolescent; D002648:Child; D004359:Drug Therapy, Combination; D005260:Female; D006509:Hepatitis B / Q000628:therapy*; D006515:Hepatitis B virus / Q000187:drug effects / Q000254:growth & development; D006521:Hepatitis, Chronic / Q000628:therapy*; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D008297:Male; D011241:Prednisone / Q000627:therapeutic use*; D011446:Prospective Studies; D011994:Recombinant Proteins; D016896:Treatment Outcome; D014779:Virus Replication / Q000187:drug effects
chemical_list: D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D011241:Prednisone