DNA flow cytometry of epithelioid sarcoma.
DNA ploidy of paraffin-embedded tissue from 11 patients with epithelioid sarcoma and 20 control specimens (granuloma annulare and sarcoid) was studied. DNA aneuploidy was found in 64% of the epithelioid sarcomas and in none of the control samples. Aneuploidy did not correlate with necrosis, vascular invasion, or mitotic rate. There was also no association of aneuploidy with adverse outcome.
Pastel-Levy
C
C
Department of Pathology, Massachusetts General Hospital, Boston 02114.
Bell
D A
DA
Rosenberg
A E
AE
Preffer
F
F
Colvin
R B
RB
Flotte
T J
TJ
D000782:Aneuploidy; D004273:DNA, Neoplasm / Q000032:analysis* / Q000235:genetics; D004171:Diploidy; D005434:Flow Cytometry / Q000379:methods; D006801:Humans; D016612:Paraffin Embedding; D011379:Prognosis; D012189:Retrospective Studies; D012509:Sarcoma / Q000235:genetics* / Q000473:pathology; D012983:Soft Tissue Neoplasms / Q000235:genetics / Q000473:pathology
D004273:DNA, Neoplasm