title: Neurodepressive action of a piscicidal glycoside of plant, Aesculus indica (Colebr.) in fish.
abstract: Sublethal concentration (2.6 mg/l) of a triterpene based piscicidal glycoside of A. indica damaged the neurons, fibre tracts and central correlation sites for gustatory, tactile and visceral sensory impulses in medulla oblongata of fish after prolonged poisoning. The fear, sinking to bottom, lack of schooling and non discriminatory pattern in treated fish were because of neurodepression. The jerky movement, ventilatory inefficiency, swallowing air bubbles and light pinkness of gills were due to the degradation of respiratory centres in the vagal lobes of toxified fish.
authors.affiliation: Department of Zoology, H N Bahugana Garhwal University, Srinagar, India.
authors.forename: J P
authors.initials: JP
authors.lastname: Bhatt
mesh_terms: D000818:Animals; D001921:Brain / Q000187:drug effects / Q000473:pathology; D005399:Fishes; D009498:Neurotoxins / Q000302:isolation & purification / Q000494:pharmacology*; D010947:Plants, Toxic / Q000737:chemistry; D012503:Saponins / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D009498:Neurotoxins; D012503:Saponins