Neuroendocrine protein 7B2 in Prader-Willi syndrome.
7B2 is a neuroendocrine polypeptide of unknown function, the gene for which is sited near or within the chromosomal region deleted in Prader-Willi syndrome and Angelman's syndrome. Plasma immunoreactive 7B2 levels were measured in 26 individuals with Prader-Willi syndrome, and appropriate controls. Plasma 7B2 levels were within normal limits compared to the control groups, in adults with Prader-Willi syndrome. 7B2 levels in children with Prader-Willi syndrome were higher, this age-dependent variation having been previously reported in normal children.
Graham
D A
DA
Department of Paediatrics, Christchurch Hospital, New Zealand.
Abbott
G D
GD
Suzuki
Y
Y
Suzuki
H
H
Shimoda
S
S
D000293:Adolescent; D000367:Age Factors; D002648:Child; D002872:Chromosome Deletion; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D009419:Nerve Tissue Proteins; D051859:Neuroendocrine Secretory Protein 7B2; D009490:Neurosecretory Systems / Q000378:metabolism*; D010907:Pituitary Hormones / Q000097:blood*; D011218:Prader-Willi Syndrome / Q000097:blood* / Q000235:genetics
D009419:Nerve Tissue Proteins; D051859:Neuroendocrine Secretory Protein 7B2; D010907:Pituitary Hormones; C497678:SCG5 protein, human