title: [Sequential cancer of concomitant cancer?].
abstract: The generally-favoured polyp-cancer sequence hypothesis its probably wrong. The distribution of polyps in large intestine differs from that of cancer. There is evidence that different aetiological factors are involved in the genesis of polyps, their growth rate and the development to invasive cancer. Most polyps are very small (90%). They never develop a cancer. It is a diffusely abnormal state of the large bowel mucosa which renders it more liable to produce often polyps and very rare carcinoma (5%). Polyp-carcinoma concomitance is much nearer to the truth.
authors.affiliation: Zentrum für operative Medizin, Friedrich-Wilhelms-Universität, Bonn.
authors.forename: F
authors.initials: F
authors.lastname: Stelzner
mesh_terms: D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D003106:Colon / Q000473:pathology; D003111:Colonic Polyps / Q000473:pathology*; D015179:Colorectal Neoplasms / Q000473:pathology*; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D016609:Neoplasms, Second Primary / Q000473:pathology*; D012307:Risk Factors
vernacular_title: Karzinom-Sequenz oder Karzinom-Konkomitanz?