title: [Monoclonal antibodies to neuron-specific enolase in phenotyping lung cancer].
abstract: Morphological assessment of two samples of monoclonal antibodies (mcAB) to gamma-unit of neurospecific human enolase (NSE) is performed. It is established that mcABs interact in the tissue sections with neurons of the brain and spinal cord, gangliocytes of the central and peripheral nervous system this proving their specificity. 56 cases of lung carcinoma are studied using these mcABs; endocrine carcinoma was found in 11 cases, nonendocrine--in 45 cases. Neuroendocrine differentiation is revealed in 8 of 45 cases of non-small cell carcinoma; in all observations of small cell carcinoma NSE was found.
authors.forename: G A
authors.initials: GA
authors.lastname: Frank
authors.forename: Ia S-V
authors.initials: IaS
authors.lastname: Kazesalu
authors.forename: A O
authors.initials: AO
authors.lastname: Piĭrsoo
authors.forename: L V
authors.initials: LV
authors.lastname: Litvinova
authors.forename: N V
authors.initials: NV
authors.lastname: Vial'tsev
mesh_terms: D000911:Antibodies, Monoclonal; D000918:Antibody Specificity / Q000276:immunology; D002454:Cell Differentiation / Q000276:immunology; D006801:Humans; D008175:Lung Neoplasms / Q000201:enzymology* / Q000473:pathology; D009490:Neurosecretory Systems / Q000276:immunology; D010641:Phenotype; D010751:Phosphopyruvate Hydratase / Q000032:analysis*
chemical_list: D000911:Antibodies, Monoclonal; D010751:Phosphopyruvate Hydratase
vernacular_title: Monoklonal'nye antitela k neĭronspetsificheskoĭ énolaze v fenotipirovanii raka legkogo.