Duchenne muscular dystrophy.
Advances in the understanding of the genetic basis for Duchenne muscular dystrophy over the past 4 years has led to the quick application of molecular diagnostics. More recently, attention has turned towards acquiring a better understanding of dystrophin biochemistry and the pathophysiologic consequences of dystrophin deficiency.
Gorospe
J R
JR
Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, PA 15261.
Hoffman
E P
EP
D016189:Dystrophin / Q000172:deficiency / Q000235:genetics / Q000502:physiology; D015316:Genetic Therapy; D006801:Humans; D008954:Models, Biological; D009136:Muscular Dystrophies / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy
D016189:Dystrophin