title: Practicalities of localization in animal and human tumours.
abstract: Factors affecting the selection and application of localization methods for measuring tumours by NMR spectroscopy are considered, with particular regard to the S/N ratio and to contaminating signal from outside the volume of interest. Methods of assessing the performance of localization techniques are considered, and their importance for quantitative measurements and comparative studies is discussed.
authors.affiliation: CRC Clinical Magnetic Resonance Research Group, Institute of Cancer Research, Sutton, Surrey, UK.
authors.forename: M O
authors.initials: MO
authors.lastname: Leach
mesh_terms: D000818:Animals; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation; D009369:Neoplasms / Q000175:diagnosis*; D009374:Neoplasms, Experimental / Q000175:diagnosis*; D015203:Reproducibility of Results