Intranasal anticholinergic therapy of rhinorrhea.
This article reviews the role of anticholinergic therapy for the rhinorrhea that occurs in various rhinopathies, including irritant reactions, perennial nonallergic rhinitis, viral infection rhinitis, allergic rhinitis, and temperature-induced rhinitis. The use of a topical anticholinergic medication, ipratropium bromide, and its ability to inhibit methacholine and rhinitis-induced hypersecretion is emphasized. Ipratropium bromide appears to be both safe and effective in reducing this troublesome symptom.
Meltzer
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Allergy and Asthma Medical Group and Research Center, San Diego, CA.
D000281:Administration, Intranasal; D006801:Humans; D009241:Ipratropium / Q000008:administration & dosage / Q000009:adverse effects; D009297:Nasal Mucosa / Q000187:drug effects / Q000378:metabolism*; D010276:Parasympatholytics / Q000008:administration & dosage*; D012220:Rhinitis / Q000188:drug therapy*; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy; D014777:Virus Diseases / Q000188:drug therapy
D010276:Parasympatholytics; D009241:Ipratropium