title: [Relation between resorption resistance of cerebrospinal fluid and the degree of intracranial pressure].
abstract: Changes in the CSF resorption resistance in relation to the value of the intracranial pressure have been assessed in 44 cats. Changes in the intracranial pressure have been produced with fluid infusions. Between 1 to 5 infusion tests with the rate 0.012-1.8 ml/min have been performed in each animal. A relationship between CSF resorption resistance and intracranial pressure has been found. With an increase in the intracranial pressure CSF resorption resistance increased to maximum value of 34 kPa/ml per minute (255.6 mm Hg/ml per minute) at pressure 2.96 +/- 0.69 kPa (22.2 +/- 5.2 mm Hg). At the intracranial pressure about 6.7 kPa (50 mm Hg) CSF resorption resistance rapidly decreased to the value of 13.9 kPa/ml per minute (104 mm Hg/ml per minute). Later, changes have been rather slight. It is possible, that the breaking point at 6.7 kPa corresponds to the mobilisation of all ways of CSF evacuation.
authors.affiliation: Kliniki Neurochirurgii Instytutu Centrum Medycyny Doświadczalnej i Klinicznej PAN.
authors.forename: K
authors.initials: K
authors.lastname: Tychmanowicz
authors.forename: Z
authors.initials: Z
authors.lastname: Czernicki
authors.forename: G
authors.initials: G
authors.lastname: Pawłowski
authors.forename: G
authors.initials: G
authors.lastname: Stepińska
mesh_terms: D000042:Absorption / Q000187:drug effects; D000818:Animals; D002415:Cats; D002555:Cerebrospinal Fluid / Q000187:drug effects / Q000502:physiology*; D015170:Cerebrospinal Fluid Pressure / Q000187:drug effects / Q000502:physiology*; D004195:Disease Models, Animal; D005260:Female; D006849:Hydrocephalus / Q000175:diagnosis* / Q000503:physiopathology; D007260:Infusion Pumps; D007427:Intracranial Pressure / Q000187:drug effects / Q000502:physiology; D008297:Male; D008959:Models, Neurological; D012965:Sodium Chloride / Q000008:administration & dosage / Q000494:pharmacology; D013115:Spinal Canal; D013346:Subarachnoid Space
chemical_list: D012965:Sodium Chloride
vernacular_title: Zalezność oporu resorpcji płynu mózgowo-rdzeniowego od wysokości ciśnienia wewnatrzczaszkowego.