title: Carcinoma of the vulva: critical analysis of survival and treatment of recurrences.
abstract: Prognostic variables in vulvar cancer include: stage, lymph nodal status, tumour diameter, vascular space invasion, depth of invasion. Treatment must in the cost/benefit balance, be adequate to these prognostic variables and surgery is today the cornerstone in vulvar cancer management. In early stages it is possible to control the disease with personalized radical non-mutilant operations limiting the high incidence of complications of the past, without endangering the 5-year survival rate. The risk of relapses is related to some factors such as site of tumour growth, depth of tumoural infiltration, lymphnode involvement and vascular space involvement. Relapses appear earlier in the groin than in the primitive sites and cases with more than 3 effected nodes have a higher incidence of recurrences in any site. Survival in related to localization and time of relapses. The treatment of recurrence is personalized for different sites, almost always surgical, in local recurrences.
authors.affiliation: Obstetrics and Gynaecology Institute, University of Padua.
authors.forename: A
authors.initials: A
authors.lastname: Onnis
authors.forename: M
authors.initials: M
authors.lastname: Marchetti
authors.forename: T
authors.initials: T
authors.lastname: Maggino
mesh_terms: D002277:Carcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011379:Prognosis; D012008:Recurrence; D012307:Risk Factors; D013997:Time Factors; D014846:Vulvar Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*