Amphibian olfactory receptor neurons express olfactory marker protein.
Expression of olfactory marker protein (OMP) in olfactory receptor neurons (ORNs) in two amphibians was investigated by immunohistochemical methods. The OMP immunoreactivity was observed in the cilia, apical dendritic knobs, dendrites and somas of ORNs; the axons of ORNs also showed intense immunoreactivity for OMP throughout their course from the olfactory epithelium to the glomerular layer of the olfactory bulb. Seven days after olfactory nerve transection in salamander, the number of OMP-positive ORNs was markedly reduced in the ipsilateral epithelium. The results demonstrate that amphibian ORNs express OMP and confirm its phylogenetic conservation across diverse species.
Krishna
N S
NS
Department of Physiology and Biophysics, University of Kentucky College of Medicine, Lexington 40536.
Getchell
T V
TV
Margolis
F L
FL
Getchell
M L
ML
D000557:Ambystoma; D000818:Animals; D001369:Axons / Q000502:physiology / Q000648:ultrastructure; D004847:Epithelial Cells; D004848:Epithelium / Q000502:physiology; D009419:Nerve Tissue Proteins / Q000032:analysis / Q000378:metabolism*; D009474:Neurons / Q000166:cytology / Q000378:metabolism*; D051842:Olfactory Marker Protein; D009831:Olfactory Mucosa / Q000166:cytology / Q000502:physiology*; D009832:Olfactory Nerve / Q000502:physiology; D011894:Rana pipiens; D011984:Sensory Receptor Cells / Q000502:physiology* / Q000648:ultrastructure
D009419:Nerve Tissue Proteins; D051842:Olfactory Marker Protein