Response of preterm infants to hepatitis B vaccine.
Ninety-nine preterm infants with birth weights < 1750 gm had three doses of hepatitis B vaccine. Fifty-seven received the first dose when they weighed > or = 1000 gm (group 1) and 42 when they weighed > or = 2000 gm (group 2). The final seropositive rates and geometric mean titers of group 1 infants (79%, 61 mIU/ml) and group 2 infants (91%, 262 mIU/ml) were less than that of 43 normal term infants (100%, 679 mIU/ml).
Lau
Y L
YL
Department of Pediatrics, University of Hong Kong, Queen Mary Hospital.
Tam
A Y
AY
Ng
K W
KW
Tsoi
N S
NS
Lam
B
B
Lam
P
P
Yeung
C Y
CY
D000704:Analysis of Variance; D016009:Chi-Square Distribution; D004306:Dose-Response Relationship, Immunologic; D006510:Hepatitis B Antibodies / Q000097:blood; D006514:Hepatitis B Surface Antigens / Q000097:blood; D017325:Hepatitis B Vaccines / Q000276:immunology*; D006801:Humans; D007115:Immunization Schedule; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature / Q000276:immunology*; D013997:Time Factors
D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D017325:Hepatitis B Vaccines