Small GTP-binding proteins as compartmental markers.
Each intracellular compartment involved in the biosynthetic/secretory pathway of eukaryotic cells bears at its surface at least one small GTP-binding protein. Most of them belong to a distinct branch of the p21ras superfamily, the Sec4/Ypt1/rab family. Other proteins are members of the ARF family. They play a key role in the regulation of budding and targeting/fusion events occurring during protein transport.
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Unité de Génétique Somatique (URA CNRS 361), Institut Pasteur, Paris, France.
D000595:Amino Acid Sequence; D000818:Animals; D001692:Biological Transport / Q000502:physiology; D015415:Biomarkers / Q000032:analysis*; D019204:GTP-Binding Proteins / Q000032:analysis* / Q000235:genetics / Q000502:physiology; D006801:Humans; D008969:Molecular Sequence Data; D015388:Organelles / Q000502:physiology
D015415:Biomarkers; D019204:GTP-Binding Proteins