The diagnosis and treatment of Lyme disease.
Lyme disease has probably been reported for at least 80 years, with the cause unknown until the discovery of the Ixodes ricinus complex tick-borne spirochete B. burgdorferi. The incidence of diagnosed cases appears to be increasing in Kansas and elsewhere. A negative laboratory test does not exclude the possibility of the disease. At present, no accurate laboratory screen for the illness is available. The diagnosis must be considered when acute or chronic clinical manifestations reviewed in this paper appear in patients. Additional clinical criteria and modified CDC guidelines are proposed to help clinicians determine who should be treated. Current treatment recommendations are presented.
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D000658:Amoxicillin / Q000008:administration & dosage*; D002443:Ceftriaxone / Q000008:administration & dosage; D006801:Humans; D008193:Lyme Disease / Q000175:diagnosis* / Q000188:drug therapy* / Q000503:physiopathology; D011339:Probenecid / Q000008:administration & dosage*
D002443:Ceftriaxone; D000658:Amoxicillin; D011339:Probenecid