[Cholecystokinin, neurotensin and corticotropin-releasing factor, three important anorexic peptides].
This paper updates the informations on the three most important anorexigenic peptides: cholecystokinin, neurotensin and corticotropin-releasing factor. Their peripheral and/or central effects on food and water intakes as well as on dietary preferences are detailed. Their mechanisms of action and regulation are examined. This includes the interactions with classical neurotransmitters (norepinephrine, dopamine, etc...) as well as the description of the brain nuclei and neuronal networks involved. Finally, their variations in disturbed feeding behavior (hyperphagia, anorexia) in man or in animal models are reviewed.
Beck
B
B
INSERM U.308, Mécanismes de Régulation du Comportement Alimentaire, Nancy.
D000818:Animals; D001067:Appetite Depressants / Q000494:pharmacology*; D002490:Central Nervous System / Q000187:drug effects; D002766:Cholecystokinin / Q000494:pharmacology*; D003346:Corticotropin-Releasing Hormone / Q000494:pharmacology*; D005247:Feeding Behavior / Q000187:drug effects; D006801:Humans; D009496:Neurotensin / Q000494:pharmacology*; D010525:Peripheral Nerves / Q000187:drug effects
D001067:Appetite Depressants; D009496:Neurotensin; D002766:Cholecystokinin; D003346:Corticotropin-Releasing Hormone
Cholécystokinine, neurotensine et corticotropin-releasing factor, trois importants peptides anorexigènes.