[Quantification of number and function of mononuclear cells. Fc gamma receptors in children with protein-calorie malnutrition (PCM)].
Several kind of cells T membrane receptors have been recognized, between them immunoglobulins heavy chains receptors mu and gamma, they act in the antigen recognition, they are subpopulations-cells T surface-matched too. In the malnutrition protein-calorie (MPC) immunologic alterations were observed, in both cellular immune and humoral immune, for example: The immunoglobulins are increased and cellular response towards antigens is decreased. This failure can be due to dysfunction in the lymphocyte T-subpopulation. So we research if there are different number, percent and function of lymphocytes T subpopulations between children with MPC and health infant. We observed an increment of lymphocytes T gamma in number and percent in children with MPC compared with health infant (p < 0.05) However, the lymphocytes T and subpopulation gamma response to phytohemagglutinin was bad. These findings are concordant with the literature about increased in lymphocyte T gamma of children with MPC. Additionally we observed a dysfunction in this subpopulation.
Martínez-Cairo Cueto
S
S
Departamento de Inmunología, Hospital de Pediatría, Centro Médico Nacional S-XXI, IMSS, México, DF.
Gómez Corvera
R
R
Dávila Velázquez
J
J
D002452:Cell Count; D005260:Female; D006801:Humans; D007223:Infant; D007228:Infant Nutrition Disorders / Q000276:immunology*; D008297:Male; D010835:Phytohemagglutinins; D011502:Protein-Energy Malnutrition / Q000276:immunology*; D017452:Receptors, IgG / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
D010835:Phytohemagglutinins; D017452:Receptors, IgG
Cuantificación del número y la función de las células mononucleares. RFc gamma de niños con desnutrición proteico-calórica (DPC).