[Intracerebral transplants of embryonic nerve tissue result in the recovery of the ultrastructure of dystrophic neurons following hypoxia in adult rats].
Fragments of the intact rat embryonic brain cortex were transplanted into sensomotor cortex of adult Wistar rats subjected to hypoxia 26 days before surgery. Ultrastructure of the host brain was studied 4, 100, 130 days, 1.5, and 2 years after the operation using electron microscopy. The observed regeneration of ultrastructure of the host's neurons appears to be due to either recovery or de novo formation of the organelles.
Cherkasova
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D000818:Animals; D016380:Brain Tissue Transplantation; D002540:Cerebral Cortex / Q000196:embryology / Q000637:transplantation*; D005260:Female; D016332:Fetal Tissue Transplantation; D000860:Hypoxia / Q000473:pathology*; D008099:Liver / Q000196:embryology; D016031:Liver Transplantation; D008854:Microscopy, Electron; D009474:Neurons / Q000648:ultrastructure*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
Vnutrimozgovye transplantaty émbrional'noĭ nervnoĭ tkani vyzyvaiut vosstanovlenie ul'trastruktury distrofirovannykh posle gipoksii neĭronov vzroslykh krys.