title: The fibrous metaphyseal defect in early stage. Differential diagnosis to metaphysitis.
abstract: In a 22-month-old boy a fibrous metaphyseal defect (FMD) was diagnosed by radiological follow-up examinations. The initial radiological finding could not be differentiated from metaphysitis because of its early manifestation and stage. Eleven months later, magnetic resonance imaging (MRI) with Gadolinium (Gd)-DTPA demonstrated a small central area of increased signal intensity. Based on known angiographic findings with fibrous metaphyseal defects, one may hypothesize that this is best explained by a hypervascularized area.
authors.affiliation: Department of Radiology, Pediatric Radiology, University of Cologne, FRG.
authors.forename: M
authors.initials: M
authors.lastname: Dietlein
authors.forename: G
authors.initials: G
authors.lastname: Benz-Bohm
authors.forename: B
authors.initials: B
authors.lastname: Widemann
mesh_terms: D001848:Bone Diseases, Developmental / Q000000981:diagnostic imaging*; D003287:Contrast Media; D005269:Femur / Q000002:abnormalities*; D019786:Gadolinium DTPA; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009942:Organometallic Compounds; D010000:Osteitis / Q000000981:diagnostic imaging*; D004369:Pentetic Acid; D011859:Radiography; D012189:Retrospective Studies
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA