title: Marchiafava-Bignami disease: serial changes in corpus callosum on MRI.
abstract: Serial MRI findings of changes in corpus callosum lesions in two cases of Marchiafava-Bignami disease are presented. In both, MRI displayed diffuse swelling of the corpus callosum in the acute stage, thought to represent oedema and demyelination. In the chronic stage, in addition to atrophy of the corpus callosum with presumed focal necrosis, previously undescribed focal hypointensity on T2-weighted images, of unknown cause, was observed in the corpus callosum.
authors.affiliation: Department of Radiology, Seoul National University College of Medicine, Korea.
authors.forename: K H
authors.initials: KH
authors.lastname: Chang
authors.forename: S H
authors.initials: SH
authors.lastname: Cha
authors.forename: M H
authors.initials: MH
authors.lastname: Han
authors.forename: S H
authors.initials: SH
authors.lastname: Park
authors.forename: D L
authors.initials: DL
authors.lastname: Nah
authors.forename: J H
authors.initials: JH
authors.lastname: Hong
mesh_terms: D000437:Alcoholism / Q000150:complications* / Q000473:pathology / Q000534:rehabilitation; D001925:Brain Damage, Chronic / Q000175:diagnosis* / Q000473:pathology; D003337:Corpus Callosum / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009410:Nerve Degeneration / Q000502:physiology*; D009460:Neurologic Examination; D019966:Substance-Related Disorders / Q000175:diagnosis* / Q000473:pathology