Eosinophils as host cells for HIV-1.
Transient expression of HIV-1 p24 antigen was observed in eosinophils acutely infected with the HTLV-IIIB strain of HIV-1. PCR analysis of eosinophils isolated from 18 seropositive individuals showed HIV-1 sequences to be present in 2 subjects. These data suggest that eosinophils may act as host cells for HIV-1.
Conway
B
B
Infectious Diseases Unit, Massachusetts General Hospital, Boston.
Baskar
P
P
Bechtel
L J
LJ
Kaplan
J C
JC
Hirsch
M S
MS
Schooley
R T
RT
Pincus
S H
SH
D004279:DNA, Viral / Q000032:analysis; D004804:Eosinophils / Q000382:microbiology*; D015488:HIV Antigens / Q000032:analysis; D016655:HIV Core Protein p24 / Q000378:metabolism; D015658:HIV Infections / Q000097:blood*; D015497:HIV-1 / Q000254:growth & development* / Q000276:immunology; D006801:Humans; D016133:Polymerase Chain Reaction; D014779:Virus Replication
D004279:DNA, Viral; D015488:HIV Antigens; D016655:HIV Core Protein p24