title: Eosinophilia-myalgia syndrome, toxic-oil syndrome, and diffuse fasciitis with eosinophilia.
abstract: The eosinophilia-myalgia syndrome, which is associated with the ingestion of L-tryptophan that contained products, occurred as an epidemic in the United States in 1989. Eosinophilia-myalgia syndrome is similar in many ways to the toxic-oil syndrome, which occurred in Spain in 1981, and to diffuse fasciitis with eosinophilia, which has been noted since 1974 to occur sporadically. Recent studies have clarified the epidemiology, histopathology, and clinical features of eosinophilia-myalgia syndrome. These studies are reviewed, and comparisons to the related syndromes, toxic-oil syndrome and diffuse fasciitis with eosinophilia, are made.
authors.affiliation: Division of Rheumatology & Immunology, Medical University of South Carolina, Charleston 29425.
authors.forename: R M
authors.initials: RM
authors.lastname: Silver
mesh_terms: D001937:Brassica; D004802:Eosinophilia / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D016603:Eosinophilia-Myalgia Syndrome / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D005208:Fasciitis / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D005229:Fatty Acids, Monounsaturated; D006801:Humans; D010938:Plant Oils / Q000506:poisoning*; D000074262:Rapeseed Oil; D013577:Syndrome; D014481:United States / Q000453:epidemiology
chemical_list: D005229:Fatty Acids, Monounsaturated; D010938:Plant Oils; D000074262:Rapeseed Oil