Long-term effects of recombinant leukocyte alpha interferon in the treatment of chronic delta hepatitis.
A pilot study is described, in which 25 chronic CDH patients were treated with 3 MU recombinant alpha-interferon per week for 4 months. Improvement was transient and no long-term effects were noted. Side effects were well tolerated and reversible so that longer treatment and higher dosages should be possible.
Tocci
G
G
Lazzaro Spallanzani Hospital for Infectious Diseases, Rome, Italy.
Antonelli
L
L
Boumis
E
E
Colaiacomo
M
M
Guarascio
P
P
Struglia
C
C
Tossini
G
G
Visco
G
G
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002908:Chronic Disease; D005260:Female; D003699:Hepatitis D / Q000628:therapy*; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use*; D008099:Liver / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011994:Recombinant Proteins; D016896:Treatment Outcome
D007370:Interferon Type I; D011994:Recombinant Proteins