[The effect of L-carnitine and acetyl-L-carnitine on blood serum lipid peroxidation in vitro].
In the action mode of carnitine derivatives, the leading role is played by lipid transport inside the cell. Bearing in mind the important role of lipid peroxidation in lipid metabolism in the body and broad-range indications for use of carnitine derivatives in medical practice, it was decided to investigate the influence of carnitine derivatives on lipid peroxidation (LPO) in vitro to have a better understanding of the action mode of these drugs, as carnitine, according to the reported data, may affect certain LPO parameters in vivo.
Borisova
I G
IG
Fedorova
T N
TN
Trevisani
M
M
Seĭfulla
R D
RD
Trevisani
C
C
Tim
E K
EK
D000108:Acetylcarnitine / Q000494:pharmacology*; D001769:Blood / Q000187:drug effects* / Q000378:metabolism; D002331:Carnitine / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D066298:In Vitro Techniques; D015227:Lipid Peroxidation / Q000187:drug effects*; D008163:Luminescent Measurements; D016897:Respiratory Burst / Q000187:drug effects
D000108:Acetylcarnitine; D002331:Carnitine
Vliianie L-karnitina i atsetil-L-karnitina na perekisnoe okislenie lipidov syvorotki krovi in vitro.