Immunofluorescent antibody response to lactic dehydrogenase virus in different strains of mice.
The development of antibody against lactic dehydrogenase virus in five strains of mice (NZB x NZWF1, BALB/c, C.B-17, ICR and C.B-17 scid or SCID mice) was examined by indirect immunofluorescence (IIF) of infected liver sections. IIF antibody appeared 1 to 3 weeks and rose progressively 2 to 4 weeks after infection in four strains of mice (NZB x NZWF1, BALB/c, C.B-17 and ICR mice). SCID mice did not develop antibody. These results suggest that IIF may be applicable for detecting LDV infection in many other ordinary strains of mice.
Hayashi
T
T
Laboratory of Veterinary Pathology, University of Yamaguchi, Japan.
Mori
I
I
Noguchi
Y
Y
Itoh
T
T
Saitoh
M
M
D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis*; D005455:Fluorescent Antibody Technique; D007772:Lactate dehydrogenase-elevating virus / Q000276:immunology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C / Q000276:immunology / Q000382:microbiology; D008813:Mice, Inbred ICR / Q000276:immunology / Q000382:microbiology; D008814:Mice, Inbred NZB / Q000276:immunology / Q000382:microbiology; D008815:Mice, Inbred Strains / Q000276:immunology* / Q000382:microbiology; D016513:Mice, SCID / Q000276:immunology* / Q000382:microbiology; D013045:Species Specificity; D013047:Specific Pathogen-Free Organisms; D014777:Virus Diseases / Q000175:diagnosis / Q000276:immunology
D000914:Antibodies, Viral