[Effect of combined preventive use of quadevit with antibiotics on the survival and humoral immune response in experimental studies].
An attempt to correct with quadevit immunodepression due to prophylactic administration of benzylpenicillin and gentamicin for 6 days provided positive results. There was a significant increase in the quantities of Ig 19S and Ig 7S after the animal immunization with the bacterial antigen, an increase in the number of the AFCs in the spleen of the albino mice in response to administration of sheep erythrocytes and an increase in the survival rate of the animals with salmonellosis. The simultaneous use of quadevit with cefamezine and erythromycin did not lower the unfavourable influence of the antibiotics on the immune status of the animals.
Kynina
E S
ES
Nikitin
A V
AV
Dziubak
S T
ST
Vitvitskiĭ
V M
VM
Nikiforchin
R N
RN
Smolinskaia
L E
LE
Viktorovskiĭ
V V
VV
D000596:Amino Acids / Q000008:administration & dosage* / Q000494:pharmacology; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000494:pharmacology; D000907:Antibodies, Bacterial / Q000096:biosynthesis*; D000921:Antibody-Producing Cells / Q000187:drug effects* / Q000276:immunology; D003300:Copper / Q000008:administration & dosage* / Q000494:pharmacology; D004195:Disease Models, Animal; D004338:Drug Combinations; D004357:Drug Synergism; D051379:Mice; D011188:Potassium / Q000008:administration & dosage* / Q000494:pharmacology; D011817:Rabbits; D051381:Rats; D012481:Salmonella Infections, Animal / Q000276:immunology / Q000401:mortality / Q000517:prevention & control*; D012486:Salmonella typhimurium / Q000187:drug effects* / Q000276:immunology; D013154:Spleen / Q000473:pathology*; D013997:Time Factors; D014815:Vitamins / Q000008:administration & dosage* / Q000494:pharmacology
D000596:Amino Acids; D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D004338:Drug Combinations; D014815:Vitamins; C013233:quadevit; D003300:Copper; D011188:Potassium
Vliianie kombinirovannogo profilakticheskogo primeneniia kvadevita s antibiotikami na vyzhivaemost' i gumoral'nyĭ immunnyĭ otvet v éksperimente.