[Inhibition of eight natural foods on mutagenic effect by aflatoxin B1 and extracts of fungi].
Eight natural foods were tested for their antimutagenic activities on AFB1, metabolic extracts of A. versicolor and A. ochraceus which induced mutagenic activity in TA 98 and TA 100 mutants. The tested substances were extracted repeatedly with acetone. The revertance induced by AFB1, metabolic extracts of A. versicolor and A. ochraceus were significantly decreased when the eight natural foods were added into the medium. The results showed that the eight natural foods had different degrees of anti-mutagenic effect in vitro, suggesting that anti-mutagenic substances were present in these natural foods. It is considered that these foods may be practically valuable in the chemoprophylaxis of liver cancer in men.
Ruan
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CC
Guangxi Cancer Institute, Nanning.
D016604:Aflatoxin B1 / Q000633:toxicity*; D016587:Antimutagenic Agents / Q000494:pharmacology*; D001230:Aspergillus; D001235:Aspergillus ochraceus; D009152:Mutagenicity Tests; D009754:Nuts; D010936:Plant Extracts / Q000494:pharmacology; D012486:Salmonella typhimurium / Q000235:genetics; D012624:Seaweed; D013662:Tea
D016587:Antimutagenic Agents; D010936:Plant Extracts; D013662:Tea; D016604:Aflatoxin B1