title: Orbital cellulitis caused by Eikenella corrodens.
abstract: Eikenella corrodens is a gram-negative, facultative anaerobic bacillus with specific culture and growth requirements and unusual antibacterial susceptibilities. It has only recently been recognized as a human pathogen. Ocular and adnexal infections with this organism are rare especially in children. We treated two children with orbital cellulitis caused by E. corrodens. One was an 8-year-old boy; the other was an 11-year-old girl. Orbital cellulitis in both patients occurred after an upper respiratory tract infection. Sinusitis and a subperiosteal abscess were present in both patients. Eikenella corrodens and Streptococcus viridans were isolated from the boy; E. corrodens was the sole isolate in the girl. Intravenous ampicillin, prolonged hospitalization, and surgical drainage of the orbit were required to control the infection in both patients. Eikenella corrodens must be considered in the differential diagnosis of orbital cellulitis in children, and ophthalmologists must become familiar with the characteristics of this peculiar organism.
authors.affiliation: Department of Ophthalmology, University of Maryland School of Medicine, Baltimore.
authors.forename: R
authors.initials: R
authors.lastname: Hemady
authors.forename: A
authors.initials: A
authors.lastname: Zimmerman
authors.forename: B W
authors.initials: BW
authors.lastname: Katzen
authors.forename: J W
authors.initials: JW
authors.lastname: Karesh
mesh_terms: D000667:Ampicillin / Q000627:therapeutic use; D002481:Cellulitis / Q000188:drug therapy / Q000382:microbiology*; D002648:Child; D004322:Drainage; D016124:Eikenella corrodens; D015818:Eye Infections, Bacterial; D005260:Female; D016905:Gram-Negative Bacterial Infections; D006801:Humans; D008297:Male; D009916:Orbital Diseases / Q000188:drug therapy / Q000382:microbiology*; D012141:Respiratory Tract Infections / Q000150:complications; D012852:Sinusitis / Q000382:microbiology
chemical_list: D000667:Ampicillin