title: [Synthesis of molluscacidal synergists].
abstract: Chemical molluscicides are useful in schistosomiasis control. A synergist can potentiate the efficacy and reduce the dosage of a molluscicide, thus decreasing the toxicity and environmental pollution. In order to search for potential molluscicidal synergists, 13 compounds of O,O-dialkyl-O-(2-substituted-3-benzofurylacetonitrile-alpha-oxi mino)phosphate or thiophosphate (VI1-13) and 2 compounds of O,O-dialkyl-O-(2-thienylacetonitrile-alpha-oximino)phosphate (X14,15) were prepared. Preliminary test demonstrated that compound X15 had strong synergic effect with sodium pentachlorophenol in combating mollusks. Compounds X14 and VI1,2,3,6,8,10,12,13, also showed some molluscicidal synergistic activity.
authors.affiliation: Nanjing Institute of Materia Medica.
authors.forename: S W
authors.initials: SW
authors.lastname: Wang
authors.forename: R
authors.initials: R
authors.lastname: Wang
authors.forename: S X
authors.initials: SX
authors.lastname: Peng
mesh_terms: D000818:Animals; D004357:Drug Synergism; D008975:Molluscacides / Q000138:chemical synthesis*; D012908:Snails
chemical_list: D008975:Molluscacides