title: Microbial transformation of benzocyclobutene to benzocyclobutene-1-ol and benzocyclobutene-1-one.
abstract: Oxidation of benzocyclobutene by intact cells of Pseudomonas fluorescens 127-68 XVII, containing naphthalene dioxygenase, yielded exclusively benzylic oxidation products; benzocyclobutene-1-ol and benzocyclobutene-1-one. No evidence for incorporation of oxygen into the aromatic ring was found.
authors.affiliation: Biocatalysis Group-Organic Chemicals & Polymers Laboratory, Dow Chemical Company, Midland, Michigan 48674.
authors.forename: P E
authors.initials: PE
authors.lastname: Swanson
mesh_terms: D001711:Biotransformation; D003503:Cyclobutanes / Q000737:chemistry / Q000493:pharmacokinetics*; D049308:Dioxygenases; D009097:Multienzyme Complexes / Q000378:metabolism*; D010105:Oxygenases / Q000378:metabolism*; D011551:Pseudomonas fluorescens / Q000378:metabolism*
chemical_list: D003503:Cyclobutanes; D009097:Multienzyme Complexes; D010105:Oxygenases; D049308:Dioxygenases; C038703:naphthalene dioxygenase