[Obtaining liposomal preparations of various biologically active substances by the method of detergent flow analysis].
It was shown that detergent dialysis could be successfully used for liposomal encapsulation of substances belonging to different chemical groups with diverse therapeutic activity such as rifampicin, aclarubicin, amphotericin B, pefloxacin and insulin. Liposome encapsulation of substances poorly soluble or insoluble in aqueous media was likely the most promising. The optimal incorporation depended on both the composition of the lipids forming the liposomes and the properties of the compounds being encapsulated.
Griaznova
N S
NS
Petiushenko
R M
RM
Beliavskaia
I V
IV
Berezovskaia
L N
LN
Zhukov
V G
VG
Sviridov
B D
BD
Sazykin
Iu O
IuO
Navashin
S M
SM
D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002784:Cholesterol / Q000008:administration & dosage; D004337:Drug Carriers; D004655:Emulsions; D017022:Flow Injection Analysis / Q000379:methods; D007328:Insulin / Q000008:administration & dosage*; D008081:Liposomes; D010713:Phosphatidylcholines / Q000008:administration & dosage; D012426:Russia; D013229:Stearic Acids / Q000008:administration & dosage; D014810:Vitamin E / Q000008:administration & dosage
D000900:Anti-Bacterial Agents; D004337:Drug Carriers; D004655:Emulsions; D007328:Insulin; D008081:Liposomes; D010713:Phosphatidylcholines; D013229:Stearic Acids; D014810:Vitamin E; D002784:Cholesterol
Poluchenie liposomal'nykh preparatov razlichnykh biologicheski aktivnykh veshchestv metodom detergentnogo protochnogo analiza.