Skin nodules and macules resembling vasculitis in the antiphospholipid syndrome--a report of two cases.
Two patients who demonstrated skin lesions in the presence of antiphospholipid antibodies are documented. The first had a long history of recurrent painful nodules. She had also suffered two deep vein thromboses. The second developed a rash on the lower limbs resembling vasculitis which did not respond to prednisolone, but to low dose salicylate therapy. Histology in both patients revealed microthrombosis of cutaneous vessels.
Asherson
R A
RA
Lupus/Arthritis Research Unit, Rayne Institute, St Thomas' Hospital, London.
Jacobelli
S
S
Rosenberg
H
H
Mckee
P
P
Hughes
G R
GR
D000328:Adult; D016736:Antiphospholipid Syndrome / Q000473:pathology*; D005260:Female; D006801:Humans; D008833:Microcirculation / Q000473:pathology; D012867:Skin / Q000098:blood supply; D012871:Skin Diseases / Q000473:pathology*; D013927:Thrombosis / Q000473:pathology; D014657:Vasculitis / Q000473:pathology