[Clinical-experimental testing of the effects of a new hypnotic on respiratory function in healthy subjects and in patients with chronic-obstructive syndrome].
In a placebo-controlled double-blinded study with ten healthy volunteers and ten patients with obstructive airway disease, the effect of the test compound on respiratory function was measured. Results show that in healthy persons as well patients with obstructive lung disease of slight to moderate degree respiratory functions were not impaired.
Mühlberger
F
F
Bernische Höhenklinik Bellevue, Montana.
D000328:Adult; D004155:Diphenhydramine / Q000008:administration & dosage / Q000627:therapeutic use*; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use*; D008140:Lorazepam / Q000008:administration & dosage / Q000627:therapeutic use*; D008173:Lung Diseases, Obstructive / Q000188:drug therapy*; D008297:Male; D011446:Prospective Studies; D012119:Respiration / Q000187:drug effects*
D004338:Drug Combinations; D006993:Hypnotics and Sedatives; C077724:Somnium; D004155:Diphenhydramine; D008140:Lorazepam
Klinisch-experimentelle Prüfung eines neuen Hypnotikums auf die Atemfunktion gesunder Probanden und Patienten mit chronisch-obstruktivem Syndrom.