[Effect of monoamines on the responses of frog spinal motor neurons mediated by non-NMDA glutamate receptors].
Adrenaline, dopamine and 5-hydroxytryptamine enhanced fast desensitizing responses of frog spinal motoneurons evoked by L-glutamic acid. Monoamines also enhanced late components of dorsal root EPSP's of motoneurons. These effects of monoamines were prevented by ketamine. Slow in desensitizing responses evoked by L-glutamic acid and EPSP's of motoneurons evoked by stimulation of the reticular formation were not influenced by monoamines.
Abramets
I I
II
Samoĭlovich
I M
IM
D000818:Animals; D004298:Dopamine / Q000494:pharmacology*; D018492:Dopamine Antagonists; D004558:Electric Stimulation; D004837:Epinephrine / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D005071:Evoked Potentials / Q000187:drug effects; D007649:Ketamine / Q000494:pharmacology; D009046:Motor Neurons / Q000187:drug effects*; D011898:Ranidae; D017470:Receptors, Glutamate / Q000187:drug effects*; D012701:Serotonin / Q000494:pharmacology*; D012702:Serotonin Antagonists / Q000494:pharmacology; D013116:Spinal Cord / Q000166:cytology / Q000187:drug effects*
D018492:Dopamine Antagonists; D017470:Receptors, Glutamate; D012702:Serotonin Antagonists; D012701:Serotonin; D007649:Ketamine; D004298:Dopamine; D004837:Epinephrine
Vliianie monoaminov na otvety motoneĭronov spinnogo mozga liagushek, oposreduemye neNMDA-glutamatnymi retseptorami.