title: Prospective study of short and ultrashort regimens of gonadotropin-releasing hormone agonist in an in vitro fertilization program.
abstract: OBJECTIVE
  To assess the usefulness of the ultrashort regimen of gonadotropin-releasing hormone agonist (GnRH-a) in ovulation induction in an in vitro fertilization (IVF) program.
  
  
  METHODS
  A prospective randomized trial comparing short and ultrashort regimens of GnRH-a.
  
  
  METHODS
  Aberdeen Assisted Reproduction Unit.
  
  
  METHODS
  Forty-eight patients having IVF for the first time were randomized between the two protocols.
  
  
  METHODS
  Response to ovarian stimulation and occurrence of spontaneous luteinizing hormone (LH) surges.
  
  
  RESULTS
  In ovulation induction, fertilization, and pregnancy rates the ultrashort regimen produces results that were no different to the short regimen but it did not always prevent an LH surge.
  
  
  CONCLUSIONS
  The ultrashort regimen can be a useful alternative for ovarian stimulation of patients undergoing IVF.
authors.affiliation: Department of Obstetrics and Gynaecology, University of Aberdeen, Aberdeen Maternity Hospital, Scotland.
authors.forename: U
authors.initials: U
authors.lastname: Acharya
authors.forename: S
authors.initials: S
authors.lastname: Irvine
authors.forename: M
authors.initials: M
authors.lastname: Hamilton
authors.forename: A
authors.initials: A
authors.lastname: Templeton
mesh_terms: D000328:Adult; D002064:Buserelin / Q000008:administration & dosage* / Q000627:therapeutic use; D006063:Chorionic Gonadotropin / Q000627:therapeutic use; D004624:Embryo Transfer; D004958:Estradiol / Q000097:blood; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007986:Luteinizing Hormone / Q000378:metabolism; D009640:Norethindrone / Q000627:therapeutic use; D010062:Ovulation Induction / Q000379:methods*; D011247:Pregnancy; D011446:Prospective Studies
chemical_list: D006063:Chorionic Gonadotropin; D004958:Estradiol; D007986:Luteinizing Hormone; D002064:Buserelin; D009640:Norethindrone