title: Safety and efficacy of autologous blood donation before elective aortic valve operation.
abstract: Although the use of preoperative autologous blood donations for patients undergoing elective cardiac operations has increased dramatically in recent years, patients awaiting elective aortic valve replacement have traditionally been denied access to preoperative autologous blood collection programs. We report our experience with 79 patients, each of whom donated 1 to 3 units of autologous blood before an aortic valve operation. All patients had serious aortic valve disease as evidenced by symptoms and preoperative catheterization data. The patients collectively made 129 blood donations. One patient had a syncopal episode within 2 hours of donation and recovered without difficulty. Of the patients who gave autologous blood preoperatively, 68% avoided any homologous blood donor exposure during their subsequent hospitalization for aortic valve replacement. In contrast, in a group of 298 patients who did not give autologous blood preoperatively, only 31% avoided homologous blood exposure during aortic valve replacement (p < 0.0001). Our experience suggests that preoperative autologous blood donation by patients awaiting elective aortic valve replacement is both safe and effective. Patients with aortic valve disease should not be routinely excluded from preoperative blood services.
authors.affiliation: Department of Pathology, New England Deaconess Hospital, Boston, Massachusetts 02215.
authors.forename: W H
authors.initials: WH
authors.lastname: Dzik
authors.forename: A G
authors.initials: AG
authors.lastname: Fleisher
authors.forename: D
authors.initials: D
authors.lastname: Ciavarella
authors.forename: K J
authors.initials: KJ
authors.lastname: Karlson
authors.forename: G E
authors.initials: GE
authors.lastname: Reed
authors.forename: R L
authors.initials: RL
authors.lastname: Berger
mesh_terms: D000328:Adult; D000368:Aged; D001022:Aortic Valve Insufficiency / Q000601:surgery / Q000628:therapy*; D001024:Aortic Valve Stenosis / Q000601:surgery / Q000628:therapy*; D001804:Blood Transfusion, Autologous / Q000379:methods / Q000592:standards* / Q000706:statistics & numerical data; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008404:Massachusetts; D008875:Middle Aged; D009518:New York; D011300:Preoperative Care / Q000592:standards; D012017:Referral and Consultation