[The use of pectin-containing enterosorbents in exposure to radionuclides and heavy metals].
The pectin-vitamin composition (PVC) and its complex with active carbon (AC) was investigated for use as an oral sorbent to protect radionuclide (Sr-85, Cs-137) accumulation. PVC is composed of the natural mixture of cellulose, pectin (Ca-salt), flavonoides, vitamins of the B-group, PP and C. Investigation of PVC radioprotective action was carried out on the two groups of rats (n = 30) which received 1306 Bk/animal of Sr-85 or 343 Bk/animal of Cs-137 daily. One of the group of rats received every day also 300 mg of PVC. After 30 days level of Sr-85 was less by 56.6%, level of Cs = 137 was less by 27.6% in PVC-treated than in the control group (P < 0.05). Composite sorbent consisting of PVC and AC was slightly less effective in removing of Sr and Cs.
Trakhtenberg
I M
IM
Litenko
V A
VA
Dereviago
I B
IB
Demchenko
P I
PI
Mikhaĭlovskiĭ
S V
SV
D000818:Animals; D002588:Cesium Radioisotopes / Q000493:pharmacokinetics; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D016061:Enterosorption / Q000379:methods*; D005260:Female; D006801:Humans; D008670:Metals / Q000493:pharmacokinetics / Q000506:poisoning*; D010368:Pectins / Q000627:therapeutic use*; D011041:Poisoning / Q000378:metabolism / Q000628:therapy; D011833:Radiation Injuries, Experimental / Q000378:metabolism / Q000628:therapy*; D051381:Rats; D013326:Strontium Radioisotopes / Q000493:pharmacokinetics; D014815:Vitamins / Q000627:therapeutic use
D002588:Cesium Radioisotopes; D004338:Drug Combinations; D008670:Metals; D013326:Strontium Radioisotopes; D014815:Vitamins; D010368:Pectins
Primenenie pektinosoderzhashchikh énterosorbentov pri vozdeĭstvii radionuklidov i tiazhelykh metallov.