title: Devascularization of the anterior cruciate ligament by synovial stripping in rabbits. An experimental model.
abstract: In rabbits, synovial stripping of the anterior cruciate ligament was performed, and histologic and mechanical changes were followed up to 2 months. The operation did not immediately affect the strength of the ligament or its histological structure. However, a gradual deterioration of mechanical properties, associated with collagen necrosis and an ineffectual reparative response, was evident. Thus, synovial stripping of the ligament with the attendant concomitant devascularization leads to ligamentary insufficiency despite the lack of structural damage to the ligament by the contusion itself.
authors.affiliation: Department of Chemical Pathology, Sackler School of Medicine, Tel Aviv University, Israel.
authors.forename: D
authors.initials: D
authors.lastname: Robinson
authors.forename: N
authors.initials: N
authors.lastname: Halperin
authors.forename: Z
authors.initials: Z
authors.lastname: Nevo
mesh_terms: D000818:Animals; D016118:Anterior Cruciate Ligament / Q000098:blood supply / Q000473:pathology / Q000601:surgery*; D001696:Biomechanical Phenomena; D002452:Cell Count; D005069:Evaluation Studies as Topic; D005347:Fibroblasts; D006984:Hypertrophy; D007593:Joint Instability / Q000473:pathology / Q000503:physiopathology; D009336:Necrosis; D011817:Rabbits; D000074402:Synovectomy; D013583:Synovial Membrane / Q000098:blood supply / Q000473:pathology