[Evaluation of the usefulness of enzyme tests for the diagnosis of the effects of various organic solvents in the conditions of occupational exposure].
The aim of the study was to evaluate the suitability of enzymatic tests for estimating the effects of organic solvents upon the organisms of daily exposed workers. The analysis was undertaken in 572 workers exposed to such solvents as toluene, xylene, cresols and benzine. Periodical examination was carried out for the purposes of the study. The level of excreting organic solvents' metabolites in urine and serum enzymes' activity were determined. Also, the activity of alanine and aspartate aminotransferases and of plasmatic cholinesterase was determined. The results of the study support the necessity of applying the enzymatic tests as a basic method of evaluating the toxic activity of organic solvents.
Zawierta
J
J
Katedry i Zakładu Biochemii Pomorskiej Akademii Medycznej, Szczecinie.
Machoy
Z
Z
D000395:Air Pollutants, Occupational / Q000633:toxicity*; D000410:Alanine Transaminase / Q000097:blood*; D001219:Aspartate Aminotransferases / Q000097:blood*; D002802:Cholinesterases / Q000097:blood*; D004796:Clinical Enzyme Tests / Q000379:methods*; D004738:Engineering / Q000592:standards*; D004789:Enzyme Activation / Q000187:drug effects; D006801:Humans; D006838:Hydrocarbons / Q000592:standards / Q000633:toxicity*; D008452:Maximum Allowable Concentration; D016273:Occupational Exposure; D011044:Poland; D012997:Solvents / Q000592:standards / Q000633:toxicity*
D000395:Air Pollutants, Occupational; D006838:Hydrocarbons; D012997:Solvents; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D002802:Cholinesterases
Ocena przydatności testów enzymatycznych w diagnozowaniu oddziaływań róznych rozpuszczalników organicznych w warunkach ekspozycji przemysłowej.