title: Intranasal anticholinergic therapy of rhinorrhea.
abstract: This article reviews the role of anticholinergic therapy for the rhinorrhea that occurs in various rhinopathies, including irritant reactions, perennial nonallergic rhinitis, viral infection rhinitis, allergic rhinitis, and temperature-induced rhinitis. The use of a topical anticholinergic medication, ipratropium bromide, and its ability to inhibit methacholine and rhinitis-induced hypersecretion is emphasized. Ipratropium bromide appears to be both safe and effective in reducing this troublesome symptom.
authors.affiliation: Allergy and Asthma Medical Group and Research Center, San Diego, CA.
authors.forename: E O
authors.initials: EO
authors.lastname: Meltzer
mesh_terms: D000281:Administration, Intranasal; D006801:Humans; D009241:Ipratropium / Q000008:administration & dosage / Q000009:adverse effects; D009297:Nasal Mucosa / Q000187:drug effects / Q000378:metabolism*; D010276:Parasympatholytics / Q000008:administration & dosage*; D012220:Rhinitis / Q000188:drug therapy*; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy; D014777:Virus Diseases / Q000188:drug therapy
chemical_list: D010276:Parasympatholytics; D009241:Ipratropium