title: [Transient, prolonged, combined sicca syndrome of the eyes and mouth. Occurrence along with a common cold in an 8-year-old girl].
abstract: A girl of eight years fell ill with signs of common cold and bronchitis. Already on the second day of illness, before any treatment was started, she showed symptoms of a sicca-syndrome, beginning in the eyes, later the mouth. Ophthalmologic examination showed keratitis filiformis, histology of the salivary glands in the mucosa of the mouth was normal. Local substitution therapy led to subjective improvement. The disorder of secretion persisted for four months only, then rapid restitutio ad integrum of tears and saliva production occurred. Pathogenetically a parainfectious immunologic mechanism seems probable. During the observed period there were significant changes of antibody titers against RS-virus and streptococci, but it is not possible to identify the cause of the illness really. We conclude that a sicca-syndrome with normal histology of mouth-mucosa-glands is not necessarily prognostically infavorable.
authors.affiliation: Universitäts-Kinderklinik, Tübingen.
authors.forename: H
authors.initials: H
authors.lastname: Rebmann
authors.forename: J M
authors.initials: JM
authors.lastname: Rohrbach
authors.forename: A
authors.initials: A
authors.lastname: Riester
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis; D002648:Child; D002701:Chloramphenicol / Q000008:administration & dosage; D003139:Common Cold / Q000150:complications* / Q000276:immunology; D003907:Dexamethasone / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004917:Erythromycin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007638:Keratoconjunctivitis Sicca / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D009883:Ophthalmic Solutions / Q000008:administration & dosage; D012136:Respiratory Syncytial Viruses / Q000276:immunology; D012859:Sjogren's Syndrome / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D014987:Xerostomia / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D009883:Ophthalmic Solutions; D004917:Erythromycin; D002701:Chloramphenicol; D003907:Dexamethasone
vernacular_title: Passageres, protrahiertes, kombiniertes Sicca-Syndrom der Augen und des Mundes. Auftreten im Rahmen eines grippalen Infekts bei einem 8jährigen Mädchen.