Asthma classification by a score calculated from clinical findings and examinations in subjects sensitive to inhalant allergens.
Twenty-one patients with atopic asthma were classified into three types according to their symptoms (clinical diagnosis): Ia, simple bronchoconstriction; Ib, bronchoconstriction + hypersecretion; and II, bronchiolar obstruction, and this classification was compared with a classification made according to clinical findings and examinations (score diagnosis). Type Ib asthma was characterized by the increased incidence of eosinophils in bronchoalveolar lavage fluid (BALF), while type II was characterized by ventilatory dysfunction in small airways and the increased incidence of neutrophils in BALF. Four patients, whose expectoration was between 50 and 99ml/day, of the 12 with type Ia assessed by clinical diagnosis were evaluated as type Ib by score diagnosis. One patient with type II by clinical diagnosis was assessed as questionable type II by score diagnosis. In the other 16 patients, the clinical and score diagnoses were the same.
Tanizaki
Y
Y
Misasa Medical Branch, Okayama University Medical School, Tottori, Japan.
Kitani
H
H
Okazaki
M
M
Mifune
T
T
Mitsunobu
F
F
Tanimizu
M
M
Honke
N
N
Kusaura
Y
Y
Ochi
K
K
Harada
H
H
D000280:Administration, Inhalation; D000328:Adult; D000368:Aged; D001249:Asthma / Q000145:classification* / Q000175:diagnosis; D001985:Bronchial Provocation Tests; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged