title: Radiohistology and histochemistry of barium granuloma of the colon and rectum.
abstract: Barium granuloma of the colon and rectum is a rare complication of X-ray examination of the digestive tract using barium. The authors report 5 new cases occurring in the last 3 years. Histological examination revealed a granulomatous reaction with greyish finely granular refractile PAS-negative material located in the cytoplasm of histiocytes and in the interstitial space. The radiographic study of the paraffin blocks confirmed the nature of this material, which was X-ray opaque, and this was corroborated histochemically with the rhodizonate technique.
authors.affiliation: Department of Pathology and Radiology, National Hospital Marqués de Valdecilla, Santander, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Mayorga
authors.forename: F
authors.initials: F
authors.lastname: Castro
authors.forename: F
authors.initials: F
authors.lastname: Fernández
authors.forename: F
authors.initials: F
authors.lastname: Val-Bernal
authors.forename: V
authors.initials: V
authors.lastname: Arribas
mesh_terms: D000368:Aged; D001466:Barium Sulfate / Q000009:adverse effects*; D003108:Colonic Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006099:Granuloma / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000473:pathology*; D006651:Histocytochemistry; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D008297:Male; D008875:Middle Aged; D016612:Paraffin Embedding; D011859:Radiography; D012002:Rectal Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging / Q000473:pathology*
chemical_list: D001466:Barium Sulfate