Lipid-related clotting reactions of clinical significance.
Several lipid-related reactions involving coagulation and fibrinolytic mechanisms have been described. Many of these reactions have been related to the development of atherosclerosis and thromboembolism. In this article, I review the antiphospholipid antibody syndrome, the tissue factor pathway inhibitor, the involvement of fatty acids in fibrinolysis, and the Lp(a) lipoprotein.
Bowie
E J
EJ
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minn. 55905.
D017152:Antibodies, Antiphospholipid / Q000032:analysis; D001161:Arteriosclerosis / Q000378:metabolism; D001777:Blood Coagulation / Q000502:physiology*; D005342:Fibrinolysis / Q000502:physiology; D006801:Humans; D008055:Lipids / Q000097:blood*; D017270:Lipoprotein(a) / Q000097:blood; D008074:Lipoproteins / Q000378:metabolism; D014280:Triglycerides / Q000097:blood
D017152:Antibodies, Antiphospholipid; D008055:Lipids; D017270:Lipoprotein(a); D008074:Lipoproteins; D014280:Triglycerides; C051928:lipoprotein-associated coagulation inhibitor