title: [Mouse serum inhibition of cytotoxicity of goat antibodies against mouse thymocytes].
abstract: It is shown that the serum of Balb/c, C57Bl/6 and F1(C57Bl/6 x CBA) mice inhibits cytotoxicity of goat antithymocyte antibodies. The addition of the serum into the incubation medium increases the proportion of alive cells from -5% up to 95%. Cytotoxicity was also inhibited by the globulin fraction of the mice serum. It is suggested that normal mice serum contains factors which block cytotoxicity of antibodies against antigen host determinants.
authors.forename: F V
authors.initials: FV
authors.lastname: Donenko
authors.forename: A O
authors.initials: AO
authors.lastname: Kabieva
authors.forename: Iu T
authors.initials: IuT
authors.lastname: Volkov
authors.forename: L V
authors.initials: LV
authors.lastname: Moroz
mesh_terms: D000818:Animals; D000906:Antibodies / Q000032:analysis; D002478:Cells, Cultured; D003601:Cytotoxicity Tests, Immunologic; D003602:Cytotoxicity, Immunologic; D006041:Goats; D007136:Immunoglobulins / Q000032:analysis; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D000906:Antibodies; D007136:Immunoglobulins
vernacular_title: Ingibirovanie tsitotoksichnosti koz'ikh antitel protiv timotsitov myshi syvorotkoĭ mysheĭ.