title: Primary epiphyseal transplants and bone overgrowth in childhood amputations.
abstract: Seventeen children aged newborn to 14 years underwent major through-bone amputations or revision at our two institutions. Ten patients (group 1) had primary autogenous epiphyseal transplants taken from the amputated limb and used to cap the open medullary canal of the residual limb. Seven patients (group 2) did not have epiphyseal transplants. Nine of 10 patients in group 1 (90%) had no problems related to bone overgrowth or delay in prosthetic fitting. In group 2, six of seven patients (86%) had clinically symptomatic bony overgrowth of 20 months after the index amputation on the average. Four patients had surgical revisions. Therefore, provided healthy autogenous donor epiphyses are available, we recommend primary epiphyseal transplants to avoid the complications of bone overgrowth in childhood through-bone amputations.
authors.affiliation: Department of Orthopaedic Surgery, Case Western Reserve University Schools of Medicine, Cleveland, Ohio.
authors.forename: J
authors.initials: J
authors.lastname: Benevenia
authors.forename: J T
authors.initials: JT
authors.lastname: Makley
authors.forename: M C
authors.initials: MC
authors.lastname: Leeson
authors.forename: K
authors.initials: K
authors.lastname: Benevenia
mesh_terms: D000293:Adolescent; D000671:Amputation, Surgical / Q000009:adverse effects / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D004838:Epiphyses / Q000637:transplantation*; D005260:Female; D006801:Humans; D015576:Hyperostosis / Q000209:etiology / Q000517:prevention & control*; D007223:Infant; D008297:Male; D012086:Reoperation; D012189:Retrospective Studies