Mechanisms of ciliary movement: contributions from electron microscopy.
A brief review of important contributions of electron microscopy to the study of ciliary motility is presented. The electron microscope was used to show the universality of axonemal structure of cilia, and to develop the sliding microtubule model of ciliary motility and later the switch point hypothesis to explain the conversion of sliding into bending. Unexpectedly, insights into the importance of cilia in human health have stemmed from these studies.
Satir
P
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Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, Bronx, NY 10461.
D002465:Cell Movement; D002923:Cilia / Q000502:physiology* / Q000648:ultrastructure*; D006801:Humans; D008854:Microscopy, Electron / Q000379:methods; D008870:Microtubules / Q000502:physiology