title: Indication, efficiency and complications of intrathecal pump supported baclofen treatment in spinal spasticity.
abstract: In 19 patients, who suffered from severe spinal spasticity of different etiologies and did not respond sufficiently to oral antispastic therapy, intrathecal Baclofen test boli were administered. In 11 patients a DAD (Drug Administration Device) [SynchroMedR Model 8611 H, Medtronic Inc. Minneapolis, USA] was implanted. Catheter dislocation or torsion was the most common complication to be observed in these 11 patients. Long term intrathecal Baclofen application was effective in all patients, as reducing spasticity, flexor spasms and spasm induced pain. In some cases the motor performance ameliorated.
authors.affiliation: Department of Neurology, University Hospital, Innsbruck, Austria.
authors.forename: L
authors.initials: L
authors.lastname: Saltuari
authors.forename: M
authors.initials: M
authors.lastname: Kronenberg
authors.forename: M J
authors.initials: MJ
authors.lastname: Marosi
authors.forename: M
authors.initials: M
authors.lastname: Kofler
authors.forename: L
authors.initials: L
authors.lastname: Russegger
authors.forename: C
authors.initials: C
authors.lastname: Rifici
authors.forename: P
authors.initials: P
authors.lastname: Bramanti
authors.forename: F
authors.initials: F
authors.lastname: Gerstenbrand
mesh_terms: D000328:Adult; D001418:Baclofen / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006391:Hemangioma / Q000150:complications; D006801:Humans; D007260:Infusion Pumps / Q000009:adverse effects; D007278:Injections, Spinal; D008297:Male; D009103:Multiple Sclerosis / Q000150:complications*; D009128:Muscle Spasticity / Q000188:drug therapy* / Q000209:etiology; D012021:Reflex, Abnormal / Q000187:drug effects; D013124:Spinal Injuries / Q000150:complications*; D013125:Spinal Neoplasms / Q000150:complications; D014554:Urination / Q000187:drug effects
chemical_list: D001418:Baclofen