Peptidergic modulation of learning a motoric food-procuring conditioned reflex skill.
Experimental data are presented which were obtained during an investigation of the influence of various doses of a synthetic heptapeptide based on tafcine on the learning of a complex instrumental skill in dogs. The effectiveness of the intranasal application of the peptide in the early stages of learning was demonstrated, as was its capacity to restore the lost skill. The vegetative support of the motoric reactions during the modulation of the learning by the peptide was investigated.
Petukhova
E G
EG
Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences, Moscow.
Kozlovskaya
M M
MM
D000161:Acoustic Stimulation; D000818:Animals; D003214:Conditioning, Classical / Q000187:drug effects*; D004285:Dogs; D004562:Electrocardiography; D004576:Electromyography; D005247:Feeding Behavior / Q000187:drug effects*; D005260:Female; D007858:Learning / Q000187:drug effects*; D008297:Male; D009479:Neuropeptides / Q000502:physiology*; D013239:Stereotyped Behavior / Q000187:drug effects; D014405:Tuftsin / Q000494:pharmacology*
D009479:Neuropeptides; D014405:Tuftsin