[A SOS induction test screening study for vegetables inhibiting mutagenicity caused by antineoplastic drugs].
Using mutational and anti-mutational synchronous in SOS inductest (+/- S9), We found that 7 out of 11 kinds of commonly eaten vegetables had the ability to inhibit mutagenicity caused by chemical drugs such as Mitomycin C, Bleomycinia, Fluorouracil, Cis-Diaminodichloroplatinum, Arabinosylcytosin and mustargen, They were garlic, green Chinese onion, onion, garlic bulb, tomato, cucumber and water radish. The other 4 lacking this ability were rape, chinese toon, ginger and asparagus lettuce stalk. We believe that our results can be helpful in the preparation. of cancer patients' diet, who are receiving chemotherapy and in the prevention of cancer.
Zhao
Z Z
ZZ
Hebei Cancer Institute, Shijiazhuang.
Huang
M T
MT
D016587:Antimutagenic Agents / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000633:toxicity*; D004926:Escherichia coli; D005472:Fluorouracil / Q000633:toxicity; D016685:Mitomycin / Q000633:toxicity; D009152:Mutagenicity Tests; D010936:Plant Extracts / Q000494:pharmacology; D013014:SOS Response, Genetics / Q000187:drug effects; D014675:Vegetables
D016587:Antimutagenic Agents; D000970:Antineoplastic Agents; D010936:Plant Extracts; D016685:Mitomycin; D005472:Fluorouracil