End-stage liver disease in a 31-year-old man.
This is a case of decompensated chronic liver disease associated with FZ phenotype AAT deficiency. Histologic confirmation of the diagnosis was aided by immunostaining of the AAT globules. Liver transplantation was successful in reversing the disease process.
Sherman
K E
KE
Dept. of Medicine, Fitzsimons Army Medical Center, Aurora, CO 80045.
Goodman
Z D
ZD
D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D008103:Liver Cirrhosis / Q000175:diagnosis / Q000201:enzymology / Q000235:genetics; D017093:Liver Failure / Q000175:diagnosis* / Q000201:enzymology / Q000235:genetics; D008171:Lung Diseases / Q000209:etiology; D008297:Male; D010641:Phenotype; D000515:alpha 1-Antitrypsin / Q000235:genetics; D019896:alpha 1-Antitrypsin Deficiency
D000515:alpha 1-Antitrypsin