[Glycosaminoglycans in syrinogomyelia].
Excretion of glycosaminoglycans (GAG) with urine was 2.7-fold decreased in patients with syringomyelia as compared with healthy persons. Patterns of GAG decreased excretion are genetically determined and inherited as dominant features. Content of GAG was decreased in the patients skin, cerebrospinal fluid and brain by 30%, 40% and 20-40%, respectively; content of GAG was increased by 80% in spinal cord where the pathological process was localized. The data obtained suggest that considerable impairment of connective tissue metabolism occurred in syringomyelia.
Elaev
N R
NR
Safin
Sh M
ShM
Borisova
N A
NA
Kamilov
F Kh
FKh
D001923:Brain Chemistry; D003238:Connective Tissue / Q000378:metabolism; D006025:Glycosaminoglycans / Q000134:cerebrospinal fluid / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D012867:Skin / Q000737:chemistry; D013595:Syringomyelia / Q000134:cerebrospinal fluid / Q000378:metabolism* / Q000652:urine
D006025:Glycosaminoglycans
Glikozaminoglikany pri siringomielii.