title: Petrous apex cholesteatoma: diagnostic and treatment dilemmas.
abstract: The diagnosis and treatment of petrous apex cholesteatoma is a difficult surgical challenge. This study is a review of 14 cases of cholesteatoma involving the petrous apex. These cholesteatomas originated as a congenital primary lesion or secondary to an acquired lesion. The cases were evaluated according to the clinical features, the intraoperative findings, the radiological findings, and the surgical approaches. In this series, 83% of the patients presented with hearing loss and 50% presented with facial nerve weakness or paralysis (House grade II to VI). Intraoperative and radiological features revealed frequent direct labyrinthine and supralabyrinthine cell spread. The transpetrous surgical approach was used in all cases. The main factors affecting the surgical approach to be adopted are the inaccessible nature of the petrous apex, the extent of disease, the degree of facial nerve function, and the need for the prevention of cerebrospinal fluid leaks and the recurrence of the lesion.
authors.affiliation: Department of Otoneurosurgery, Addenbrooke's Hospital, Cambridge, England.
authors.forename: M D
authors.initials: MD
authors.lastname: Atlas
authors.forename: D A
authors.initials: DA
authors.lastname: Moffat
authors.forename: D G
authors.initials: DG
authors.lastname: Hardy
mesh_terms: D000328:Adult; D000368:Aged; D001847:Bone Diseases / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D002558:Cerebrospinal Fluid Otorrhea / Q000209:etiology; D002781:Cholesteatoma / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D003051:Cochlea / Q000601:surgery; D007758:Ear, Inner / Q000473:pathology / Q000601:surgery; D005154:Facial Nerve / Q000473:pathology / Q000503:physiopathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010579:Petrous Bone / Q000473:pathology*; D011183:Postoperative Complications; D012189:Retrospective Studies