Antimicrobial activity of naphtoquinones and Allium extracts combined with antibiotics.
Combinations of antibiotics and known antimicrobial natural products, naphtoquinones and Allium extracts, were investigated. The chessboard broth method was applied to assess the activity of these combinations against aerobic and anaerobic bacteria. If no antagonism was observed, the combinations studied lead from partial to total synergism, mainly against aerobic bacteria.
Didry
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N
Laboratoire de Matière médicale, Faculté de Pharmacie, Lille.
Dubreuil
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L
Pinkas
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M
D000490:Allium / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D004357:Drug Synergism; D008826:Microbial Sensitivity Tests; D009285:Naphthoquinones / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D009285:Naphthoquinones; D010936:Plant Extracts