title: Effect of nickel on some aspects of protein metabolism in selected organs of the freshwater mussel Lamellidens marginalis.
abstract: The levels of soluble, structural and total proteins, and the activities of A1AT and AAT decreased along with an increase in the levels of free amino acids and the activity of protease in the ctenidium, hepatopancreas and foot of the freshwater mussel L. marginalis after 1, 2, 3 and 4 d of exposure to a lethal concentration (115 mg.L-1) of nickel. But the activity of GDH and the level of urea decreased in the hepatopancreas and increased in the ctenidium and foot. A reverse trend was observed in the level of ammonia. In a sublethal concentration (23 mg.L-1), the levels of soluble, structural and total proteins and ammonia decreased in these three organs of the mussel after 1, 5, 10 and 15 d of exposures, with an increase in the levels of free aminoacids, urea and in the activities of protease, A1AT, AAT and GDH. The extent of these changes differed in degree depending on exposure period in the lethal and sublethal concentrations. The results are discussed in order to arrive at the degree of metal stress on the overall nitrogen metabolism of the mussel according to the period of exposure to lethal and sublethal concentrations of nickel.
authors.affiliation: Department of Zoology Sri Krishnadevaraya University, Anantapur, India.
authors.forename: P
authors.initials: P
authors.lastname: Sreedevi
authors.forename: B
authors.initials: B
authors.lastname: Sivaramakrishan
authors.forename: A
authors.initials: A
authors.lastname: Suresh
authors.forename: K
authors.initials: K
authors.lastname: Radhakrishanaiah
mesh_terms: D000818:Animals; D049872:Bivalvia / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism*; D009532:Nickel / Q000009:adverse effects*; D011506:Proteins / Q000378:metabolism*
chemical_list: D011506:Proteins; D009532:Nickel