[High density lipoproteins in the blood of rats of varying age].
The study revealed age-related changes in the content and ratio of apoproteins which are part of high-density lipoproteins (HDL), as well as the development of dysapolipoproteinemia. The most significant fall (by 46.7%) was found in the content of the key HDL apoprotein--apoA1, and rise (by 107%)--in apoE. The development of dysapolipoproteinemia was accompanied by changes in the lipid composition of HDL and their subfractions (HDL2 and HDL3). HDLs were enriched by cholesterol and its esters. HDL cholesterol/apoA1 ratio increased twice, while the content of phospholipids decreased.
Frol'kis
V V
VV
Bogatskaia
L N
LN
Novikova
S N
SN
Potanpenko
R I
RI
Mozzhukhina
T G
TG
Sabko
V E
VE
D000375:Aging / Q000097:blood*; D000818:Animals; D001059:Apoproteins / Q000097:blood; D001161:Arteriosclerosis / Q000276:immunology*; D001798:Blood Proteins / Q000032:analysis; D007113:Immunity, Innate / Q000502:physiology; D008055:Lipids / Q000097:blood; D008075:Lipoproteins, HDL / Q000097:blood* / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar
D001059:Apoproteins; D001798:Blood Proteins; D008055:Lipids; D008075:Lipoproteins, HDL
Lipoproteiny vysokoĭ plotnosti v krovi krys raznogo vozrasta.