[Acceleration of epidermis proliferation by direct current stimulation (an experimental study)].
An experimental study was designed to evaluate the effect of direct current stimulation on the rate of epidermis proliferation using guinea pigs. In the study, two full thickness skin defects were made over the paravertebral region in each animal. The edges of wounds were transfixed. One of the wounds in each animal received the DC stimulation, and the other did not. The 44 animals were divided into four groups of eleven animals each, the stimulation strengths were 10 muADC, 30 muADC, 50 muADC, 0 muADC respectively. The results showed that the rate of epidermal cell proliferation and wound healing with the DC stimulation were faster, especially on the side of the negative electrode, and the rate of healing of the unstimulated wound in animals which received stimulation in the contralateral wound was faster than that of wounds of control animals.
Jiang
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Department of Plastic Surgery, Changhai Hospital, Second Military Medical University.
D000818:Animals; D002452:Cell Count; D004599:Electric Stimulation Therapy / Q000379:methods; D004817:Epidermis / Q000254:growth & development*; D005260:Female; D006168:Guinea Pigs; D008297:Male; D012883:Skin Ulcer / Q000473:pathology / Q000503:physiopathology* / Q000628:therapy; D014945:Wound Healing