Flexibilized gelatin film-based artificial skin model: I. Preparation and properties of the films.
A method was developed to prepare a simple, flexibilized gelatin film-based artificial skin model. The films are tough, adhere to open wounds spontaneously, are permeable to body fluids, and can release incorporated bioactive compounds over 4-5 days.
Shinde
B G
BG
Center for Protein and Polymer Research, Albert Einstein Medical Center, Philadelphia, Pennsylvania 19141.
Nithianandam
V S
VS
Kaleem
K
K
Erhan
S
S
D004353:Drug Evaluation, Preclinical; D005780:Gelatin / Q000737:chemistry / Q000627:therapeutic use*; D006801:Humans; D008422:Materials Testing; D008567:Membranes, Artificial; D010539:Permeability; D013718:Tensile Strength; D000267:Tissue Adhesions; D014945:Wound Healing; D014947:Wounds and Injuries / Q000188:drug therapy* / Q000503:physiopathology
D008567:Membranes, Artificial; C015233:gelatin film; D005780:Gelatin