title: Computed tomography appearance of bone metastases of leiomyosarcoma.
abstract: Bone lesions in leiomyosarcoma are uncommon. When encountered, they are usually a late manifestation of disease seen in the setting of widespread systemic metastases. We present five cases of metastatic leiomyosarcoma, including one in which a bone lesion predated detection of a primary gastric leiomyosarcoma and one in which bone metastases signaled disease recurrence. Computed tomography in 14 of 16 osseous leiomyosarcomas demonstrated a lytic, non-expansile pattern.
authors.affiliation: Russel H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, Maryland.
authors.forename: C C
authors.initials: CC
authors.lastname: Meltzer
authors.forename: E K
authors.initials: EK
authors.lastname: Fishman
authors.forename: W W
authors.initials: WW
authors.lastname: Scott
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D005260:Female; D005266:Femoral Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D006801:Humans; D007414:Intestinal Neoplasms / Q000473:pathology; D007421:Intestine, Small / Q000473:pathology; D007890:Leiomyosarcoma / Q000000981:diagnostic imaging* / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D013125:Spinal Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D013274:Stomach Neoplasms / Q000473:pathology; D015996:Survival Rate; D014057:Tomography, X-Ray Computed; D014594:Uterine Neoplasms / Q000473:pathology