title: [Non-Hodgkin's lymphoma in childhood: 19-year experience in a pediatric oncology unit].
abstract: Ninety-one patients with Non-Hodgkin's Lymphoma (NHL) were treated in our Pediatric Oncology Unit during a 19 year period. The median age at diagnosis was 5.8 years and there was a higher incidence in males. All patients were classified according to Murphy's stages and Rappaport's modified classification. Advanced disease and non-lymphoblastic histology were prevailing. Chemotherapy was the preferred treatment. Forty-seven patients (54%) are alive with a median follow-up period of 6.2 years. Actuarial survival rate at 5 years is 0.6. Advances in chemotherapy led to an increase in NHL patient's survival. Twenty patients died because of the disease and 21 because of fatal complications.
authors.affiliation: Unidad de Oncología Pediátrica, Hospital Infantil La Fe, Valencia.
authors.forename: A
authors.initials: A
authors.lastname: Cañete Nieto
authors.forename: V
authors.initials: V
authors.lastname: Castel Sánchez
authors.forename: C
authors.initials: C
authors.lastname: Esquembre Menor
authors.forename: M
authors.initials: M
authors.lastname: Hernández Martí
authors.forename: A
authors.initials: A
authors.lastname: Verdeguer Miralles
authors.forename: J
authors.initials: J
authors.lastname: Ferris Tortajada
mesh_terms: D000367:Age Factors; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008228:Lymphoma, Non-Hodgkin / Q000145:classification / Q000188:drug therapy / Q000401:mortality* / Q000473:pathology; D008297:Male; D012737:Sex Factors; D013030:Spain / Q000453:epidemiology; D015996:Survival Rate
vernacular_title: Linfomas no Hodgkin en la infancia: 19 años de experiencia en una unidad de oncología pediátrica.