title: Spontaneous resolution of pre-eclampsia-related thrombocytopenia.
abstract: OBJECTIVE
  To observe the spontaneous resolution of pre-eclampsia-related thrombocytopenia.
  
  
  METHODS
  A retrospective study.
  
  
  METHODS
  High Risk Pregnancy Unit, John Radcliffe Maternity Hospital, Oxford.
  
  
  METHODS
  Thirty women with pre-eclampsia complicated by the HELLP/ELLP syndrome who did not receive any specific treatment for their thrombocytopenia.
  
  
  METHODS
  Serial platelet counts throughout labour and the puerperium until the platelet counts returned to levels above 100 x 10(9)/l.
  
  
  METHODS
  Time taken from delivery and platelet nadir for platelet counts to return to levels above 100 x 10(9)/l. The rate of recovery from the platelet nadir was measured by the slope of the serial platelet counts plotted against time.
  
  
  RESULTS
  The mean time until platelet count exceeded 100 x 10(9)/l was 67 h (SD 25) after delivery and 44 h (SD 17) from the platelet nadir. All women had counts above 100 x 10(9)/l by 111 h after delivery, and by 88 h after the platelet nadir. Although the time to recovery appeared to depend on the degree of thrombocytopenia, the rate of resolution did not.
  
  
  CONCLUSIONS
  These data can be used as a guide by clinicians as to the expected time course for postpartum resolution of pre-eclampsia-related thrombocytopenia.
authors.affiliation: Nuffield Department of Obstetrics and Gynaecology, University of Oxford, John Radcliffe Maternity Hospital, UK.
authors.forename: R
authors.initials: R
authors.lastname: Chandran
authors.forename: V
authors.initials: V
authors.lastname: Serra-Serra
authors.forename: C W
authors.initials: CW
authors.lastname: Redman
mesh_terms: D000293:Adolescent; D000328:Adult; D001792:Blood Platelets; D005260:Female; D017359:HELLP Syndrome / Q000097:blood*; D006801:Humans; D010976:Platelet Count; D011247:Pregnancy; D012075:Remission, Spontaneous; D012189:Retrospective Studies; D013997:Time Factors