[Effect of low doses of external and internal ionizing radiation on proteinases of cells in the rat cerebral cortex of rats].
Single external gamma-irradiation in a dose of 0.5-2 Gy as well as the long-term (30 days) internal irradiation caused by the everyday influx of Cs-137 and Sr-85 isotopes to the organism have been studied for their effect on the activity and properties of histone-specific proteinase from the nuclei of the rat brain cortex cells. It is found out that external irradiation induces a dose-dependent increase of the activity during the first 24 hours after irradiation followed by its decrease 7-30 days later. Internal irradiation induces a decrease of the enzyme activity at the 30th day as well. Certain specificity of the studied indices depending on the type of irradiation has been also observed.
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D000818:Animals; D002467:Cell Nucleus / Q000201:enzymology / Q000528:radiation effects; D002540:Cerebral Cortex / Q000166:cytology / Q000201:enzymology / Q000528:radiation effects*; D002588:Cesium Radioisotopes; D002843:Chromatin / Q000201:enzymology; D010450:Endopeptidases / Q000528:radiation effects*; D005720:Gamma Rays; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013326:Strontium Radioisotopes
D002588:Cesium Radioisotopes; D002843:Chromatin; D013326:Strontium Radioisotopes; D010450:Endopeptidases
Vliianie nizkikh doz vneshnego i vnutrennego ioniziruiushchego izlucheniia na svoĭstva proteinaz kletok kory golovnogo mozga krys.