title: [The use of nefopam in the prophylaxis and treatment of postoperative shivering].
abstract: Chlorhydrate nefopam was used in the prophylaxis and treatment of postoperative shivering in 54 patients undergoing general anesthesia for radical cystectomy with trans-intestinal anastomosis. Postoperative shivering was not observed in any of the patients treated with nefopam before coming round, whereas it occurred in 55% of patients treated with placebo. Chlorhydrate nefopam subsequently stopped shivering in all these patients. The main side effects observed took the form of delayed awakening in 11% of patients receiving prophylactic treatment and somnolence lasting 5-10 minutes in all other patients.
authors.affiliation: Istituto di Anestesiologia e Rianimazione, Università degli Studi di Torino.
authors.forename: A
authors.initials: A
authors.lastname: Tempia
authors.forename: S
authors.initials: S
authors.lastname: Livigni
authors.forename: P M
authors.initials: PM
authors.lastname: Castino
authors.forename: G
authors.initials: G
authors.lastname: Fiore
authors.forename: D
authors.initials: D
authors.lastname: De Caroli
authors.forename: R
authors.initials: R
authors.lastname: Pattono
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009340:Nefopam / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000188:drug therapy*; D012768:Shivering / Q000187:drug effects*
chemical_list: D009340:Nefopam
vernacular_title: Impiego del nefopam nella profilassi e nella terapia del brivido postoperatorio.