[The use of nefopam in the prophylaxis and treatment of postoperative shivering].
Chlorhydrate nefopam was used in the prophylaxis and treatment of postoperative shivering in 54 patients undergoing general anesthesia for radical cystectomy with trans-intestinal anastomosis. Postoperative shivering was not observed in any of the patients treated with nefopam before coming round, whereas it occurred in 55% of patients treated with placebo. Chlorhydrate nefopam subsequently stopped shivering in all these patients. The main side effects observed took the form of delayed awakening in 11% of patients receiving prophylactic treatment and somnolence lasting 5-10 minutes in all other patients.
Tempia
A
A
Istituto di Anestesiologia e Rianimazione, Università degli Studi di Torino.
Livigni
S
S
Castino
P M
PM
Fiore
G
G
De Caroli
D
D
Pattono
R
R
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009340:Nefopam / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000188:drug therapy*; D012768:Shivering / Q000187:drug effects*
D009340:Nefopam
Impiego del nefopam nella profilassi e nella terapia del brivido postoperatorio.