title: Antioxidant status (selenium, vitamins A and E) and aging.
abstract: Antioxidant status can be evaluated by blood selenium, vitamins A and E. The level of selenium was determined in whole blood, erythrocytes and plasma of 170 French people (70-95 years old) healthy and with intercurrent illness, by using PIXE (proton-induced X-ray emission analysis). These results are discussed with other values from the literature. Plasma levels of vitamins A and E have been measured by HPLC. All data were compared with those obtained for younger subjects. Healthy elderly people residing in a geriatric home received selenium supplements during 1 month. The influence of this supplementation brought to light a deficiency for this trace element. The correlation of aging and nutritional requirements with immune function, heart and cancer death rate is presented and discussed.
authors.affiliation: Centre d'Etudes Nucléaires de Bordeaux-Gradignan URA 451 du CNRS, France.
authors.forename: M
authors.initials: M
authors.lastname: Simonoff
authors.forename: C
authors.initials: C
authors.lastname: Sergeant
authors.forename: N
authors.initials: N
authors.lastname: Garnier
authors.forename: P
authors.initials: P
authors.lastname: Moretto
authors.forename: Y
authors.initials: Y
authors.lastname: Llabador
authors.forename: G
authors.initials: G
authors.lastname: Simonoff
authors.forename: C
authors.initials: C
authors.lastname: Conri
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000097:blood*; D000975:Antioxidants / Q000378:metabolism*; D002318:Cardiovascular Diseases / Q000097:blood*; D004032:Diet; D005260:Female; D005527:Food, Fortified; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000097:blood*; D012016:Reference Values; D012643:Selenium / Q000097:blood*; D012727:Sex Characteristics; D014801:Vitamin A / Q000097:blood*; D014810:Vitamin E / Q000097:blood*
chemical_list: D000975:Antioxidants; D014801:Vitamin A; D014810:Vitamin E; D012643:Selenium