title: Interaction between bacteriophage lambda and its Escherichia coli host.
abstract: Bacteriophage lambda relies to a large extent on processes requiring interactions between viral- and host-encoded proteins for its lytic growth, establishment of lysogeny, and release from the prophage state. Both biochemical and genetic studies of these interactions have yielded new information about important host and lambda functions. In particular, mutations in Escherichia coli that compromise lambda DNA replication, genome packaging, transcription elongation, and site-specific recombination have led to the identification of bacterial genes whose products are chaperones, transcription factors, or DNA-binding proteins.
authors.affiliation: University of Michigan, Ann Arbor.
authors.forename: D I
authors.initials: DI
authors.lastname: Friedman
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism; D010582:Bacteriophage lambda / Q000235:genetics / Q000502:physiology*; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism; D004926:Escherichia coli / Q000235:genetics / Q000502:physiology*; D015964:Gene Expression Regulation, Bacterial; D015967:Gene Expression Regulation, Viral; D008242:Lysogeny; D016601:RNA-Binding Proteins / Q000235:genetics / Q000378:metabolism; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism; D014775:Virus Activation; D016662:Virus Integration; D014779:Virus Replication
chemical_list: D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; D016601:RNA-Binding Proteins; D014764:Viral Proteins; C069331:rexB protein, Bacteriophage lambda