title: Lectin-like activity of Lactobacillus acidophilus strain JCM 1026.
abstract: The lectin-like activity of the Lactobacillus acidophilus strain JCM 1026 was studied by hemagglutination and hemagglutination-inhibition assays. L. acidophilus strain JCM 1026 was found to hemagglutinate human and animal erythrocytes. Neuraminidase-treatment of human-type O erythrocytes enhanced the activity. Treatment of the bacterial cells with proteinase K reduced hemagglutinating activity significantly. Although several mono- and disaccharides did not inhibit hemagglutination, several different glycoproteins did. These data indicate that a proteinaceous lectin-like component(s) recognizing carbohydrate-containing molecules is located on the cell surface of L. acidophilus.
authors.affiliation: School of Veterinary Medicine and Animal Sciences, Kitasato University, Towada-shi, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Mukai
authors.forename: K
authors.initials: K
authors.lastname: Arihara
authors.forename: H
authors.initials: H
authors.lastname: Itoh
mesh_terms: D000818:Animals; D006023:Glycoproteins / Q000494:pharmacology; D006384:Hemagglutination / Q000187:drug effects; D006385:Hemagglutination Inhibition Tests; D006386:Hemagglutination Tests; D006801:Humans; D066298:In Vitro Techniques; D007779:Lactobacillus acidophilus / Q000276:immunology*; D037102:Lectins / Q000302:isolation & purification* / Q000494:pharmacology; D009439:Neuraminidase / Q000494:pharmacology
chemical_list: D006023:Glycoproteins; D037102:Lectins; D009439:Neuraminidase