title: [The results of the clinical use of the immobilized-protease enzyme profezim in treating exacerbated chronic periodontitis].
abstract: The authors characterize the action of profezyme, an immobilized proteinase enzyme, used in the treatment of patients with exacerbations of chronic periodontitis. Time course of symptomatology was followed up in 65 patients in various periods of periodontitis therapy. Prolonged enzymic therapy helped reduce the length of treatment by 2-3 times.
authors.forename: S A
authors.initials: SA
authors.lastname: Lebedev
authors.forename: L E
authors.initials: LE
authors.lastname: Smolianko
authors.forename: V K
authors.initials: VK
authors.lastname: Leont'ev
mesh_terms: D002908:Chronic Disease; D004341:Drug Evaluation; D006801:Humans; D010518:Periodontitis / Q000188:drug therapy*; D013381:Subtilisins / Q000627:therapeutic use*
chemical_list: D013381:Subtilisins
vernacular_title: Rezul'taty klinicheskogo primeneniia fermenta immobilizovannykh proteaz profezima v lechenii khronicheskogo periodontita v stadii obostreniia.