MR imaging in acute multiple sclerosis: ringlike appearance in plaques suggesting the presence of paramagnetic free radicals.
MR studies in three patients with multiple sclerosis have shown clearly defined rings within plaques of demyelination, having signal characteristics consistent with the presence of paramagnetic material. It is suggested that these appearances represent the presence of free radicals in the macrophage layer forming the margin of an acute plaque.
Powell
T
T
Department of Neuroradiology, Royal Hallamshire Hospital, Sheffield, UK.
Sussman
J G
JG
Davies-Jones
G A
GA
D000208:Acute Disease; D001921:Brain / Q000473:pathology*; D005609:Free Radicals; D006801:Humans; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis / Q000473:pathology*
D005609:Free Radicals