title: [Therapy of bacterial infections in neutropenic and immunocompromised patients].
abstract: Neutropenias, especially extended an long-lasting stages, lead to life-threatening endogenous infection. Therefore, after taking off materials for bacteriological investigations an empirical schedule of a combined high dose, treatment with broad-band antibiotics and/or antimycotics has immediately to be introduced and to continue until the body temperature and the peripheral blood granulocytes are normalized. In case of treatment failure one should complete the therapy by other additional antibiotics or correct the combination of its in respect to the results of the microbiological investigations. Supplements of this antimicrobial treatments are immunoglobulins and growth factors (G-CSF, GM-CSF). In case of an expected neutropenica the use of the selective gut decontamination or the reverse isolation of the patient can be of essential advantage.
authors.affiliation: Klinik für Innere Medizin, Universität Leipzig.
authors.forename: W
authors.initials: W
authors.lastname: Helbig
authors.forename: R
authors.initials: R
authors.lastname: Tauchnitz
mesh_terms: D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use*; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005335:Fever of Unknown Origin / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D009503:Neutropenia / Q000188:drug therapy* / Q000382:microbiology; D009894:Opportunistic Infections / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Therapie bakterieller Infektionen bei neutropenischen und immuninsuffizienten Patienten.