[Effect of epidural buprenorphine on postoperative respiratory function].
The effects of epidural buprenorphine on postoperative respiratory function were studied using respiratory inductive plethysmography (RIP) in two groups of patients [(1) 0.1 mg (2) 0.2 mg] after upper abdominal surgery. Buprenorphine 0.1 mg group showed decreased respiratory rate and increased tidal volume. Decreases in the respiratory rate and the tidal volume were seen in buprenorphine 0.2 mg group and continued for 3-4 hrs after the epidural administration. However, there was no severe respiratory depression in either group. It seems that 0.1 mg of epidural buprenorphine may give a satisfactory postoperative pain relief and less respiratory depression, and RIP is a useful method for the measurement of postoperative respiratory function.
Ichiishi
N
N
Department of Anesthesiology, Tokyo Teishin Hospital.
Hiraishi
T
T
Hara
O
O
Konishi
R
R
Osamura
Y
Y
Ashizawa
N
N
Hanaoka
K
K
D000005:Abdomen / Q000601:surgery; D002047:Buprenorphine / Q000008:administration & dosage / Q000494:pharmacology*; D003864:Depression, Chemical; D006801:Humans; D007268:Injections, Epidural; D010149:Postoperative Pain / Q000188:drug therapy / Q000503:physiopathology; D011184:Postoperative Period; D012119:Respiration / Q000187:drug effects*; D012129:Respiratory Function Tests
D002047:Buprenorphine