title: Retinoid therapy for aging skin and acne.
abstract: Primary care physicians should be familiar with the effects and appropriate uses of retinoids. Topical tretinoin (Retin-A) can reverse photoaging of the skin, although some transient, undesirable side effects usually occur. In patients with acne vulgaris, topical tretinoin and systemic isotretinoin (Accutane) are the only agents that act upon the apparent underlying causes. Recurrence is unlikely after successful results are achieved. Chronic hypervitaminosis A presents insidiously, and physicians must maintain a high index of suspicion. Complete history taking should always include questions about the patient's use of vitamin supplements.
authors.affiliation: Department of Family Practice, Hennepin County Medical Center, Minneapolis.
authors.forename: S W
authors.initials: SW
authors.lastname: Farnes
authors.forename: P A
authors.initials: PA
authors.lastname: Setness
mesh_terms: D000152:Acne Vulgaris / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D000287:Administration, Topical; D000818:Animals; D003875:Drug Eruptions / Q000209:etiology; D004359:Drug Therapy, Combination; D006801:Humans; D006986:Hypervitaminosis A / Q000139:chemically induced; D015474:Isotretinoin / Q000009:adverse effects / Q000627:therapeutic use*; D008487:Medical History Taking; D010808:Physical Examination; D015595:Skin Aging / Q000187:drug effects* / Q000528:radiation effects; D012878:Skin Neoplasms / Q000139:chemically induced; D014212:Tretinoin / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D014212:Tretinoin; D015474:Isotretinoin