Cancer cell procoagulants and their implications.
Cancer cells induce abnormal blood coagulation through a process that probably involves a combination of increased activators and deficiencies of anticoagulants. The probable participating factors (including tissue factor-factor VII and cancer procoagulant) and their role in this process are discussed. The current theory on the role of coagulation in malignant disease is also discussed.
Gordon
S G
SG
Department of Pathology and Medical Oncology, Colorado Cancer Center, Denver.
D000818:Animals; D001777:Blood Coagulation; D001778:Blood Coagulation Disorders / Q000209:etiology / Q000276:immunology; D001779:Blood Coagulation Factors / Q000378:metabolism*; D006801:Humans; D009369:Neoplasms / Q000097:blood* / Q000150:complications / Q000276:immunology
D001779:Blood Coagulation Factors