Renal function in patients undergoing cardiopulmonary bypass operations.
We evaluate short- and long-term effects on renal functional reserve of cardiopulmonary bypass in 11 patients. A selected group (persistence of renal functional reserve before operation) of 11 adult patients undergoing cardiopulmonary bypass for aorta-coronary bypass were studied. Renal functional reserve tests were performed in all patients before the operation, at postoperative day 9, and at 6 months after operation. Basal glomerular filtration rate did not show significant changes at 9 days and at 6 months after operation. On the contrary, renal functional reserve was absent at 9 days, but it was restored to preoperative levels at 6 months after operation. In conclusion, our data indicate that cardiopulmonary bypass probably causes renal damage that is not sufficient to influence routine renal function parameters.
Mazzarella
V
V
Istituto di Tipizzaazione Tissutale e problemi della dialisi-CNR di L'Aquila, Rome, Italy.
Gallucci
M T
MT
Tozzo
C
C
Elli
M
M
Chiavarelli
R
R
Marino
B
B
Casciani
C
C
D058186:Acute Kidney Injury / Q000503:physiopathology*; D000328:Adult; D002315:Cardiopulmonary Bypass / Q000009:adverse effects*; D001026:Coronary Artery Bypass; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007668:Kidney / Q000502:physiology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000503:physiopathology*