title: [Pathomorphologic verification of the prenatal diagnosis of developmental defects in trimester II fetuses].
abstract: 153 foetuses were studied obtained after the artificial abortion for genetical indications. The scheme of the material investigation is given. Isolated, systemic and multiple defects were found in 39.0, 12.1 and 48.9%, respectively, and the contribution of the syndrome forms in the multiple developmental disturbances was 60.9%. The interruption of the pregnancy in 2% of cases was assessed as unfounded: as a consequence of hyperdiagnosis and in cases of treatable defects. The frequency of the discrepancy between prenatal and pathology diagnoses was 31.8% including hyperdiagnosis of the defect (1.3%), nosological disagreement (13.3%), the lack of diagnosis of the additional defects detectable during II trimester by present ultrasound methods (17.2%). The efficacy of the work of the prenatal diagnostic centre is, according to the authors, the number of justified interruptions of pregnancy (98% in this study).
authors.forename: I A
authors.initials: IA
authors.lastname: Kirillova
authors.forename: G I
authors.initials: GI
authors.lastname: Kravtsova
authors.forename: I V
authors.initials: IV
authors.lastname: Novikova
authors.forename: G I
authors.initials: GI
authors.lastname: Laziuk
mesh_terms: D000015:Abnormalities, Multiple / Q000473:pathology*; D000032:Abortion, Therapeutic; D000013:Congenital Abnormalities / Q000473:pathology*; D005314:Embryonic and Fetal Development / Q000502:physiology; D005260:Female; D006801:Humans; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011296:Prenatal Diagnosis / Q000379:methods*; D015203:Reproducibility of Results
vernacular_title: Patomorfologicheskaia verifikatsiia prenatal'nykh diagnozov porokov razvitiia u plodov II trimestra.