Precipitous stem cell (SC) differentiation and 1/f noise.
After a brief digression on certain types of noise of generic interest, it is concluded that 1/f noise offers interesting interpretations for unusual modes of SC differentiation such as the precipitous maturation of a subset of the macrophage lineage. Functionally equivalent to weak, spurious sources these specialized cells support the proliferation and maturation of erythroid cells extending thus the stimulatory influence of true, strong sources although in a rather indirect fashion.
Matioli
G T
GT
USC School of Medicine, Los Angeles 90033.
D000818:Animals; D002454:Cell Differentiation; D006412:Hematopoietic Stem Cells / Q000166:cytology; D008938:Mitosis; D008954:Models, Biological; D011336:Probability; D013234:Stem Cells / Q000166:cytology*