Studies on antimutagenic effect of milk cultured with lactic acid bacteria on the Trp-P2-induced mutagenicity to TA98 strain of Salmonella typhimurium.
The inhibitory effects of cultured milk using 76 strains of lactic acid bacteria isolated from milk products were investigated on the mutagenicity of 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P2), a tryptophan pyrolysate for Salmonella typhimurium TA98. Each cultured milk sample displayed its characteristic antimutagenic effect against the mutagenicity of Trp-P2. The milk cultured with Lactobacillus acidophilus LA106 (LA2) showed the highest inhibition of 82.1% among the strains used. Milk samples cultured with Lactococcus lactis subsp. lactis, Lll103 (10-3) and Lll102 (KM) also exhibited higher inhibition percentages.
Hosoda
M
M
Technical Research Laboratory, Takanashi Milk Products Co. Ltd. Yokohama, Japan.
Hashimoto
H
H
Morita
H
H
Chiba
M
M
Hosono
A
A
D000818:Animals; D016587:Antimutagenic Agents / Q000378:metabolism* / Q000494:pharmacology; D002243:Carbolines / Q000494:pharmacology*; D005285:Fermentation; D006863:Hydrogen-Ion Concentration; D007779:Lactobacillus acidophilus / Q000378:metabolism*; D013294:Lactococcus lactis / Q000378:metabolism*; D008892:Milk / Q000382:microbiology*; D009153:Mutagens / Q000494:pharmacology*; D012486:Salmonella typhimurium / Q000187:drug effects
D016587:Antimutagenic Agents; D002243:Carbolines; D009153:Mutagens; C019133:3-amino-1-methyl-5H-pyrido(4,3-b)indole