title: Suspected inappropriate secretion of antidiuretic hormone in a male with mental retardation.
abstract: The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is a disorder in which a sustained release of antidiuretic hormone occurs because of certain diseases, pharmacological agents, or trauma. Fluid volume expands with a resultant hyponatremia which, depending on the degree, may be asymptomatic or result in death. This case report describes a 38-year-old male in whom SIADH was strongly suspected secondary to Tegretol therapy to control a seizure disorder. Medical consultation is imperative for these patients before administering a fluid challenge during general anesthesia.
authors.affiliation: West Virginia University Health Sciences Center, Department of Pediatric Dentistry.
authors.forename: R
authors.initials: R
authors.lastname: Steelman
authors.forename: D
authors.initials: D
authors.lastname: Holmes
mesh_terms: D000328:Adult; D000766:Anesthesia, Dental; D000768:Anesthesia, General; D002220:Carbamazepine / Q000009:adverse effects*; D000075202:Contraindications; D003730:Dental Care for Persons with Disabilities; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000139:chemically induced* / Q000175:diagnosis; D008607:Intellectual Disability; D008297:Male; D012640:Seizures / Q000188:drug therapy
chemical_list: D002220:Carbamazepine