title: [High density lipoproteins in the blood of rats of varying age].
abstract: The study revealed age-related changes in the content and ratio of apoproteins which are part of high-density lipoproteins (HDL), as well as the development of dysapolipoproteinemia. The most significant fall (by 46.7%) was found in the content of the key HDL apoprotein--apoA1, and rise (by 107%)--in apoE. The development of dysapolipoproteinemia was accompanied by changes in the lipid composition of HDL and their subfractions (HDL2 and HDL3). HDLs were enriched by cholesterol and its esters. HDL cholesterol/apoA1 ratio increased twice, while the content of phospholipids decreased.
authors.forename: V V
authors.initials: VV
authors.lastname: Frol'kis
authors.forename: L N
authors.initials: LN
authors.lastname: Bogatskaia
authors.forename: S N
authors.initials: SN
authors.lastname: Novikova
authors.forename: R I
authors.initials: RI
authors.lastname: Potanpenko
authors.forename: T G
authors.initials: TG
authors.lastname: Mozzhukhina
authors.forename: V E
authors.initials: VE
authors.lastname: Sabko
mesh_terms: D000375:Aging / Q000097:blood*; D000818:Animals; D001059:Apoproteins / Q000097:blood; D001161:Arteriosclerosis / Q000276:immunology*; D001798:Blood Proteins / Q000032:analysis; D007113:Immunity, Innate / Q000502:physiology; D008055:Lipids / Q000097:blood; D008075:Lipoproteins, HDL / Q000097:blood* / Q000737:chemistry; D051381:Rats; D017208:Rats, Wistar
chemical_list: D001059:Apoproteins; D001798:Blood Proteins; D008055:Lipids; D008075:Lipoproteins, HDL
vernacular_title: Lipoproteiny vysokoĭ plotnosti v krovi krys raznogo vozrasta.