[Drug sensitivity study of Plasmodium falciparum in the city of Yaounde (Cameroon)].
In July 1990, the in vitro chemosensitivity of 22 isolates of Plasmodium falciparum was assessed by an isotopic semi-microtest in Yaounde, Cameroon. Out of them, 54.5% were resistant to chloroquine, 28.6% to amodiaquine, 4.8% to quinine and 4.5% had a decrease of sensitivity to mefloquine. A strong positive correlation between the IC50 of the antimalarial drugs compared by pairs was detected.
Caligaris
S
S
Clinique des Maladies infectieuses et tropicales, Université de Brescia, Italie.
Fadat
G
G
Matteelli
A
A
Castelli
F
F
Kouka Bemba
D
D
Carosi
G
G
D000293:Adolescent; D000328:Adult; D000962:Antimalarials / Q000627:therapeutic use*; D002163:Cameroon / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D004351:Drug Resistance; D006801:Humans; D016778:Malaria, Falciparum / Q000097:blood / Q000188:drug therapy* / Q000453:epidemiology; D008826:Microbial Sensitivity Tests
D000962:Antimalarials
Etude de la chimiosensibilité de Plasmodium falciparum aux antimalariques dans la ville de Yaoundé (Cameroun).