title: Strain and sex differences in amphetamine-induced rotation.
abstract: Studies of rotational behavior in female rats have investigated Fischer, Sprague-Dawley, Madison, WI, and Holtzman strains. The present study of amphetamine-induced rotational preference looked at the most widely used of the pigmented strains, Long-Evans hooded rats, examining rotation in females and comparing rotational magnitude and direction to males of the same strain. We corroborate in Long-Evans animals the greater rotation of females, but our findings oppose the right-sided female and left-sided male rotational preferences reported in earlier studies. Only female rats in this experiment had a significant directional bias, and it was to the left. This result strongly points to the importance of strain in the lateralization expressed by rotation.
authors.affiliation: Department of Psychology, University of Waterloo, Ontario, Canada.
authors.forename: H J
authors.initials: HJ
authors.lastname: Storrie-Baker
authors.forename: M F
authors.initials: MF
authors.lastname: Novotny
authors.forename: D P
authors.initials: DP
authors.lastname: Crowne
mesh_terms: D000661:Amphetamine / Q000494:pharmacology*; D000818:Animals; D004971:Estrus / Q000187:drug effects; D005260:Female; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D012399:Rotation; D012727:Sex Characteristics; D013045:Species Specificity; D013239:Stereotyped Behavior / Q000187:drug effects*
chemical_list: D000661:Amphetamine