Optic neuropathy in Hodgkin's disease.
Hodgkin's disease is a rare cause of infiltrative optic neuropathy, which typically evolves late in the disease course. We managed an unusual case of isolated optic neuropathy in a 21-year-old man occurring during clinical remission from Hodgkin's disease. Radiotherapy and treatment with high-dose systemic corticosteroids resulted in dramatic improvement in vision. Even without other evidence of recurrent disease, acute-onset optic neuropathy in a patient with a history of a lymphoproliferative disorder should raise the question of a reemergence of the malignancy.
Siatkowski
R M
RM
Bascom Palmer Eye Institute, Miami, Florida.
Lam
B L
BL
Schatz
N J
NJ
Glaser
J S
JS
Byrne
S F
SF
Hughes
J R
JR
D000328:Adult; D005654:Fundus Oculi; D006689:Hodgkin Disease / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009901:Optic Nerve Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012008:Recurrence