[The prospects of using dopamine as an antishock preparation].
The quantitative evaluation of the centralization reaction for shockogenic trauma has been experimentally established as an objective criterion of circulatory homeostasis failure severity and adequacy of its correction. The highest antishock effect of dopamine is reached when cardiac output fraction addressed to thoracic region vitals is supported by dopamine on the 43-45% level. Single infusion of the new synthesized prolonged dopamine (12.5 mg/kg) supplies hemodynamic stabilization for post-trauma hypovolemia during 4 hours.
Tiukavin
A I
AI
Syrenskiĭ
A V
AV
Rubanova
N S
NS
Nadezhdina
L B
LB
Andreeva
E N
EN
Vlasov
G P
GP
D000818:Animals; D002415:Cats; D004298:Dopamine / Q000627:therapeutic use*; D005260:Female; D008297:Male; D012774:Shock, Traumatic / Q000188:drug therapy*
D004298:Dopamine
Perspektivy ispol'zovaniia dofamina kak protivoshokovogo preparata.