title: Concomitant presence of trisomy 21 and del(9q) in acute myeloid leukemia.
abstract: We report two cases of acute myeloid leukemia with deletion of the long arm of chromosome 9 [del(9q)] and trisomy 21. del(9q) and +21 do not often occur as a sole karyotypic abnormality in acute myeloid leukemia (AML). Their concomitant presence is rare; the significance of the findings in leukemia is discussed.
authors.affiliation: Haematology Section, University Department of Pathology, Queen Mary Hospital, Hong Kong.
authors.forename: Y L
authors.initials: YL
authors.lastname: Kwong
authors.forename: L C
authors.initials: LC
authors.lastname: Chan
mesh_terms: D000293:Adolescent; D000328:Adult; D002872:Chromosome Deletion; D002891:Chromosomes, Human, Pair 21; D002899:Chromosomes, Human, Pair 9; D005260:Female; D006801:Humans; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D008297:Male; D014314:Trisomy