title: Phosphate removal by resin hemoperfusion efficacy and biocompatibility of a new exchange resin.
abstract: A new coated anionic exchange resin for blood purification specifically designed to remove phosphates was experimentally employed in animals. 3 pigs, in which uremia had been surgically induced, underwent 6 extracorporeal hemoperfusion sessions (2 per pig) with a cartridge containing 100 gr of resin. The phosphate clearance proved satisfactory, values being 120 ml/min after 10' and around 80 ml/min after 2 hours. The biocompatibility of the resin and of the coating membrane was satisfactory. The negligible variation in pH and plasma bicarbonate during all sessions confirmed the low absorption by the tested resin of other blood anions competing with phosphate.
authors.affiliation: Nephrology Department, S. Orsola Hospital, Bologna, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Colì
authors.forename: S
authors.initials: S
authors.lastname: Faenza
authors.forename: M
authors.initials: M
authors.lastname: Spighi
authors.forename: L C
authors.initials: LC
authors.lastname: Borgnino
authors.forename: G
authors.initials: G
authors.lastname: Feliciangeli
authors.forename: G
authors.initials: G
authors.lastname: Cianciolo
authors.forename: A
authors.initials: A
authors.lastname: Faenza
authors.forename: G
authors.initials: G
authors.lastname: Martinelli
authors.forename: R
authors.initials: R
authors.lastname: Giardino
authors.forename: S
authors.initials: S
authors.lastname: Stefoni
mesh_terms: D000818:Animals; D001639:Bicarbonates / Q000097:blood; D001672:Biocompatible Materials; D002712:Chlorides / Q000097:blood; D006464:Hemoperfusion / Q000379:methods*; D006863:Hydrogen-Ion Concentration; D007773:Lactates / Q000097:blood; D010710:Phosphates / Q000378:metabolism; D012116:Resins, Plant; D013552:Swine
chemical_list: D001639:Bicarbonates; D001672:Biocompatible Materials; D002712:Chlorides; D007773:Lactates; D010710:Phosphates; D012116:Resins, Plant