[Hypolactasia in Japanese Crohn's patients].
20 g lactose load test, BHT and LTT done simultaneously were examined in 32 Crohn's disease patients and 51 healthy volunteers. Hypolactasia frequency were examined. A rise in hydrogen concentration > 20 parts per million (ppm) above the base line during breath hydrogen test and maximum blood sugar rise during lactose tolerance test were considered to indicated Hypolactasia. High rates, 50% by BHT and 72.5% by LTT, of primary adult hypolactasia were found in healthy volunteers as previously reported. Higher rates, 83.3% by BHT and by LTT (p < 0.05), were observed in Crohn's disease patients. There were higher rates in small intestine type Crohn's disease (91.6% by BHT, 92.3% by LTT) compare with healthy volunteers but no difference were found with large intestine type Crohn's disease.
Ogata
M
M
Department of Gastroenterology, Fukuoka University Chikushi Hospital.
Yao
T
T
D000328:Adult; D003424:Crohn Disease / Q000378:metabolism*; D005260:Female; D006801:Humans; D006859:Hydrogen / Q000032:analysis; D006863:Hydrogen-Ion Concentration; D007785:Lactose / Q000493:pharmacokinetics*; D008297:Male
D006859:Hydrogen; D007785:Lactose