title: [Detoxification treatment with naltrexone in opiate dependence].
abstract: Outcome of a maintenance treatment with naltrexone (350 mg/week) are examined in a sample of 50 patients with opiate dependence disorder. Treatment was followed in an outpatient facility, in a setting similar to patient's own environment. The average attendance rate was of 6.4 months. Six months after the onset of the treatment, 46% of the patients still remained drug-free. Results of treatment was correlated with changes in life style of the addicts. A follow-up study found that, overall, the naltrexone treatment caused an increase in alcohol consumption whereas there was a noticeable decrease in cocaine use. Factors related to successful results were a good work adjustment, no use of other drugs and lack of psychopathology.
authors.affiliation: Hospital Ramón y Cajal, Madrid.
authors.forename: E
authors.initials: E
authors.lastname: Ochoa Mangado
authors.forename: J J
authors.initials: JJ
authors.lastname: López-Ibor Aliño
authors.forename: J C
authors.initials: JC
authors.lastname: Pérez de los Cobos Peris
authors.forename: A
authors.initials: A
authors.lastname: Cebollada Gracia
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006556:Heroin Dependence / Q000523:psychology / Q000534:rehabilitation*; D006801:Humans; D008297:Male; D009271:Naltrexone / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D009271:Naltrexone
vernacular_title: Tratamiento de deshabituación con naltrexona en la dependencia de opiáceos.