Fatal perinatal nephropathy with onset in intrauterine life.
A girl, born at 29 weeks' gestation, died of renal failure aged 16 days. Postmortem histology showed diffuse mesangial sclerosis with failure of development of the cortex. This is an unusual cause of neonatal renal failure, and it demonstrates the effect of disease arising in utero and influencing the development of the kidney.
Scott
R J
RJ
Department of Histopathology, Hammersmith Hospital, London.
Rochefort
M
M
D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007668:Kidney / Q000196:embryology / Q000473:pathology*; D007678:Kidney Glomerulus / Q000473:pathology; D008854:Microscopy, Electron; D051437:Renal Insufficiency / Q000151:congenital / Q000473:pathology*