title: Hypoplasia of the corpus callosum and growth hormone deficiency in the XXXXY syndrome.
abstract: A 3-year-old Libyan boy with the XXXXY syndrome is described. MRI examination of the brain showed hypoplasia of the corpus callosum. He had growth retardation and endocrine studies demonstrated growth hormone (GH) deficiency. Dermatoglyphic pattern was different from previous reports. At histological examination of the undescended testes, Leydig cells were seen although they are usually not found in this variant of the Klinefelter syndrome.
authors.affiliation: Pediatric Department, University Hospital, Vienna, Austria.
authors.forename: G
authors.initials: G
authors.lastname: Haeusler
authors.forename: H
authors.initials: H
authors.lastname: Frisch
authors.forename: Z
authors.initials: Z
authors.lastname: Guchev
authors.forename: F
authors.initials: F
authors.lastname: Hadziselimovic
authors.forename: A
authors.initials: A
authors.lastname: Neuhold
authors.forename: W
authors.initials: W
authors.lastname: Vormittag
mesh_terms: D061085:Agenesis of Corpus Callosum; D002675:Child, Preschool; D003878:Dermatoglyphics; D006130:Growth Disorders / Q000235:genetics; D013006:Growth Hormone / Q000172:deficiency*; D006801:Humans; D007713:Klinefelter Syndrome / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D008297:Male; D013737:Testis / Q000002:abnormalities
chemical_list: D013006:Growth Hormone