title: The quinolone antibiotics.
abstract: The fluorinated quinolones are synthetic derivatives of nalidixic acid. They are well absorbed when administered orally and have an extended duration of action. They are of primary value in treating gonorrhea and complicated urinary tract infections in nonpregnant women.
authors.affiliation: Department of Obstetrics and Gynecology, University of Rochester, New York.
authors.forename: K
authors.initials: K
authors.lastname: Saravanos
authors.forename: P
authors.initials: P
authors.lastname: Duff
mesh_terms: D042462:4-Quinolones; D000818:Animals; D000890:Anti-Infective Agents / Q000009:adverse effects / Q000737:chemistry / Q000627:therapeutic use; D001424:Bacterial Infections / Q000188:drug therapy*; D003365:Costs and Cost Analysis; D005260:Female; D005831:Genital Diseases, Female / Q000188:drug therapy*; D006801:Humans; D000292:Pelvic Inflammatory Disease / Q000188:drug therapy*; D015231:Sexually Transmitted Diseases, Bacterial / Q000188:drug therapy*; D014552:Urinary Tract Infections / Q000188:drug therapy*
chemical_list: D042462:4-Quinolones; D000890:Anti-Infective Agents