Glyburide-induced cholestatic hepatitis and liver failure. Case-report and review of the literature.
As sulphonylurea derivatives are used ubiquitously, the possibility that they may cause liver disease deserves attention. In contrast to the known pattern of reversible parenchymal liver disease due to sulphonylurea derivatives, we describe a fatal case of glyburide-induced cholestatic hepatitis with liver failure.
van Basten
J P
JP
Department of Internal Medicine, University Hospital Maastricht, Netherlands.
van Hoek
B
B
Zeijen
R
R
Stockbrügger
R
R
D000368:Aged; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D002779:Cholestasis / Q000139:chemically induced*; D005260:Female; D005905:Glyburide / Q000009:adverse effects*; D006801:Humans
D005905:Glyburide