[Autoimmune paraneoplastic neurological syndromes].
Paraneoplastic neurological syndromes are well established causes of neurological dysfunction in cancer patients. Recently an auto-immune origin has been found for the Lambert-Eaton myasthenic syndrome, the subacute sensory neuronopathy of Denny-Brown, the paraneoplastic cerebellar degeneration, the paraneoplastic opsoclonus-myoclonus as well as a few other minor syndromes. Indeed patients suffering from these diseases have been found to produce antibodies directed against the central nervous system. These antibodies can be detected as much as a year before the cancer is found and they are therefore interesting for neurological and oncologic diagnosis.
Lövblad
K O
KO
Service de neurologie, CHUV Lausanne.
Steck
A J
AJ
D001327:Autoimmune Diseases / Q000276:immunology*; D002493:Central Nervous System Diseases / Q000276:immunology*; D006801:Humans; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000276:immunology*
Les syndromes paranéoplasiques neurologiques auto-immuns.