title: Isolation of spotted fever group rickettsia from Apodemus speciosus in an endemic area in Japan.
abstract: A spotted fever group rickettsia was isolated from Apodemus mice captured near the site where a person had been infected in Miyazaki Prefecture. Antigenic characteristics of the isolate designated as strain TO-1 were compared with those of Rickettsia japonica (strain YH) and Rickettsia montana (ATCC VR611) by the indirect fluorescent antibody test with 14 serum specimens obtained from Apodemus speciosus, immune rat antisera against the strains TO-1 and YH, and three patients' sera. The titers of these sera measured with strain TO-1 were identical to those with strain YH, suggesting the antigenic similarity between these two organisms. It was also suggested that Apodemus speciosus is likely to be an important vertebrate host for a spotted fever group rickettsia in Japan.
authors.affiliation: Miyazaki Prefectural Institute for Public Health and Environment.
authors.forename: S
authors.initials: S
authors.lastname: Yamamoto
authors.forename: C
authors.initials: C
authors.lastname: Morita
authors.forename: K
authors.initials: K
authors.lastname: Tsuchiya
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D000942:Antigens, Bacterial / Q000276:immunology*; D004199:Disease Vectors; D005455:Fluorescent Antibody Technique; D006801:Humans; D007564:Japan; D051379:Mice; D051381:Rats; D017208:Rats, Wistar; D012281:Rickettsia / Q000145:classification / Q000276:immunology / Q000302:isolation & purification*; D012282:Rickettsia Infections / Q000097:blood / Q000276:immunology*; D013154:Spleen / Q000382:microbiology
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial