title: Histology as a prognostic factor in early gastric cancer.
abstract: Of 431 patients with gastric cancer observed in our institution, 23 (5.3%) had early gastric cancer (EGC). Macroscopic presentation, histology, depth of invasion, and lymph node involvement were evaluated in all the cases. All patients underwent surgery and an intensive follow-up was performed. Five of the 23 patients progressed, and the risk factors were examined. Histology seemed to be the main prognostic factor in our study, since intestinal type of EGC was associated to a significantly better prognosis. Total gastrectomy is indicated in the proximal localization of EGC, and should perhaps be performed also in cases presenting undifferentiated histology.
authors.affiliation: Department of Medical Oncology, Niguarda Ca' Granda Hospital, Milan, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Ferrari
authors.forename: E
authors.initials: E
authors.lastname: Ghislandi
authors.forename: G
authors.initials: G
authors.lastname: Landonio
authors.forename: M
authors.initials: M
authors.lastname: Majno
authors.forename: T
authors.initials: T
authors.lastname: Porretta
authors.forename: F
authors.initials: F
authors.lastname: Scanzi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology*; D016019:Survival Analysis