title: Effects of aging on the diurnal pattern of water intake in rats.
abstract: This study was undertaken to confirm previous findings that Long-Evans rats exhibit age-related changes in the diurnal/nocturnal distribution of water intake and to examine the circadian pattern of these age-related changes. Twenty-one aged and 10 young pathogen-free rats were continuously monitored for water consumption over 12:12 h light/dark cycles. ANOVA, profile analysis, and cosinor analysis each demonstrated that aged rats differed from young rats. The age-related changes in circadian pattern can be described as a blunted rhythm (decreased amplitude) and an altered timing of peak activity (advanced acrophase). These differences, however, were only apparent in a subset of aged rats with the remaining aged rats exhibiting a circadian pattern indistinguishable from that of the young group.
authors.affiliation: Department of Psychology, University of North Carolina, Chapel Hill 27599-3270.
authors.forename: R D
authors.initials: RD
authors.lastname: Burwell
authors.forename: J
authors.initials: J
authors.lastname: Whealin
authors.forename: M
authors.initials: M
authors.lastname: Gallagher
mesh_terms: D000375:Aging / Q000523:psychology*; D000704:Analysis of Variance; D000818:Animals; D002940:Circadian Rhythm; D004326:Drinking; D008297:Male; D051381:Rats