title: [An experimental study on tissue induction in anterior cruciate ligament reconstruction with the scaffold-type polyester artificial ligament (Leeds-Keio)].
abstract: The effect of experimental autogenous tissue implantation (infrapatellar fat pad, fascia lata) together with scaffold type artificial ligament (Leeds-Keio) in ACL reconstruction was studied in 56 mongrel adult dogs. Specimens were examined macroscopically, histologically and by means of microangiography. The results were compared with those in which the artificial ligament was used alone. When infrapatellar fat pad was transferred on artificial ligament, tissue induction was observed 2 weeks after reconstruction. When ACL was reconstructed using a combination of artificial ligament and a small piece of fascia lata, maturated dense collagen fibers were observed 24 weeks after reconstruction. These results indicated that quicker tissue induction could be obtained in ACL reconstruction using an artificial ligament together with a infrapatellar fat pad, and that collagen fiber maturation was accelerated when ACL was reconstructed using an artificial ligament together with a small piece of fascia lata.
authors.affiliation: Department of Orthopaedic Surgery, School of Medicine, Keio University, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kawakubo
mesh_terms: D000273:Adipose Tissue; D000818:Animals; D003094:Collagen / Q000378:metabolism; D004285:Dogs; D005206:Fascia Lata; D007719:Knee Joint / Q000601:surgery*; D008023:Ligaments, Articular / Q000098:blood supply / Q000502:physiology / Q000601:surgery*; D010329:Patella; D011091:Polyesters; D019736:Prostheses and Implants; D012038:Regeneration
chemical_list: D011091:Polyesters; D003094:Collagen