title: Peripancreatic lymph node gastrinoma in a patient with Zollinger-Ellison syndrome.
abstract: The case of a patient who had Zollinger-Ellison syndrome caused by a primary peripancreatic lymph node gastrinoma is presented. Accompanying diffuse pancreatic islet cell hyperplasia, a well-documented occurrence in hypergastrinemia, was present. A perforated esophageal ulcer in a Barrett's esophagus led to right-sided necrotizing pleuritis, septicemia, and death. The diffuse parathyroid hyperplasia also noted in the patient is thought to be secondary to chronic hypertensive renal failure rather than MEN-I syndrome.
authors.affiliation: Lillian and Henry M. Stratton-Hans Popper Department of Pathology, Mount Sinai School of Medicine (CUNY), NY.
authors.forename: H
authors.initials: H
authors.lastname: Kahn
authors.forename: J
authors.initials: J
authors.lastname: Waxman
mesh_terms: D000368:Aged; D005260:Female; D015408:Gastrinoma / Q000473:pathology*; D005755:Gastrins / Q000032:analysis; D006801:Humans; D007124:Immunoenzyme Techniques; D008198:Lymph Nodes / Q000473:pathology*; D016609:Neoplasms, Second Primary / Q000473:pathology*; D010179:Pancreas / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000473:pathology*; D015043:Zollinger-Ellison Syndrome / Q000473:pathology*
chemical_list: D005755:Gastrins