Evaluation of anti-HCV positive blood donors identified during routine screening.
Of 30,231 donors tested, 368 (1.2%) were anti-HCV positive. Of these, 254 have been evaluated, with the following results: only 25% have a history of parenteral risk, seroprevalence increases with age and approximately 80% of those that are anti-HCV positive in our population are probably infected with HCV. In addition, an unexpectedly large number of these persons have chronic and/or severe liver disease and will require combined diagnostic approaches for accurate evaluation.
Esteban
J I
JI
Department of Medicine, Hospital General Universitari Vall d'Hebrón, Barcelona, Spain.
Lopez-Talavera
J C
JC
Genescà
J
J
Gonzalez
A
A
Vargas
V
V
Buti
M
M
Guardia
J
J
Esteban
R
R
D000367:Age Factors; D000410:Alanine Transaminase / Q000097:blood; D001706:Biopsy; D001782:Blood Donors; D002353:Carrier State / Q000175:diagnosis; D005260:Female; D006508:Hepatitis Antibodies / Q000097:blood*; D006526:Hepatitis C / Q000517:prevention & control*; D006521:Hepatitis, Chronic / Q000175:diagnosis; D006801:Humans; D008099:Liver / Q000473:pathology; D008297:Male; D013030:Spain / Q000453:epidemiology
D006508:Hepatitis Antibodies; D000410:Alanine Transaminase