title: Orbital involvement in Waldenström's macroglobulinemia: ultrasound, computed tomography and magnetic resonance findings.
abstract: A case of orbital involvement in Waldenström's macroglobulinemia is presented. Orbital echography, computed tomography (CT) and magnetic resonance imaging (MRI) were performed and revealed a retrobulbar mass of the right orbit. Ultrasonography suggested a lymphoid orbital tumor. A CT scan was nonspecific, but helpful in exactly locating the tumor and excluding bony lesions. Signal intensity patterns of MRI were characterized by a low intensity on T1- and T2-weighted images. A marked enhancement of the tumor was evident after intravenous injection of a paramagnetic contrast agent (gadolinium-DTPA). Although the definite diagnosis could only be established by means of an ultrasound-guided fine-needle aspiration biopsy, MRI in connection with the history of our patient strongly suggested a diagnosis of orbital lymphoma in Waldenström's disease.
authors.affiliation: Department of Ophthalmology, University of Innsbruck, Austria.
authors.forename: A R
authors.initials: AR
authors.lastname: Ettl
authors.forename: G G
authors.initials: GG
authors.lastname: Birbamer
authors.forename: W
authors.initials: W
authors.lastname: Philipp
mesh_terms: D000368:Aged; D019786:Gadolinium DTPA; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D008297:Male; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D009942:Organometallic Compounds; D004369:Pentetic Acid; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D008258:Waldenstrom Macroglobulinemia / Q000175:diagnosis* / Q000000981:diagnostic imaging
chemical_list: D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA