title: [Allergy to casein hydrolysate formula. A study of sensitizing allergen].
abstract: A six-month old baby, who had been fed for 2 months with casein hydrolysate formula (MA-1) for treatment of milk allergy, developed diarrhea. The baby's RAST score for milk was negative. IgE antibodies to MA-1 but not to MA-1 depleted of lipid (fat-free MA-1), were demonstrated by enzyme-linked immunosorbent assay (ELISA). It was confirmed by the appearance of numerous mast cells and eosinophils in a rectal smear taken after challenge with MA-1 (but not detected after challenge with fat-free MA-1) that some component in the lipid of MA-1 must be an allergen in this patient.
authors.affiliation: Department of Pediatrics, Chiba University School of Medicine.
authors.forename: N
authors.initials: N
authors.lastname: Shimojo
authors.forename: N
authors.initials: N
authors.lastname: Shimizu
authors.forename: K
authors.initials: K
authors.lastname: Hirano
authors.forename: Y
authors.initials: Y
authors.lastname: Kohno
authors.forename: H
authors.initials: H
authors.lastname: Niimi
mesh_terms: D002364:Caseins / Q000276:immunology*; D003108:Colonic Diseases / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007223:Infant; D007225:Infant Food; D008297:Male; D016269:Milk Hypersensitivity / Q000276:immunology*; D011852:Radioallergosorbent Test
chemical_list: D002364:Caseins; D007073:Immunoglobulin E