title: Sagittal split osteotomy fixed with biodegradable, self-reinforced poly-L-lactide screws. A pilot study in sheep.
abstract: Self-reinforced poly-L-lactide (SR-PLLA) screws were used to fix bilateral mandibular sagittal split osteotomies (SSO) in six sheep. No intermaxillary fixation was used postoperatively. The follow-up time was 16 weeks, after which the sheep were killed. Both sides of the mandible were photographed and radiographed. The bending strength of the osteotomy was measured on the left side of the mandible. Histological and microradiographic studies were performed on the right side of the mandible. The results showed that the SR-PLLA screws were strong enough to fix the SSO rigidly. The bending force needed to break the bone was greater than that for the average unoperated mandible. The histological and microradiographic studies showed uneventful healing of the osteotomies in all six sheep. The results indicate that this method should be suitable for rigid fixation of SSO and fractures of the mandible in human beings.
authors.affiliation: Department of Oral and Maxillofacial Surgery, University of Helsinki, Finland.
authors.forename: R
authors.initials: R
authors.lastname: Suuronen
authors.forename: P
authors.initials: P
authors.lastname: Laine
authors.forename: E
authors.initials: E
authors.lastname: Sarkiala
authors.forename: T
authors.initials: T
authors.lastname: Pohjonen
authors.forename: C
authors.initials: C
authors.lastname: Lindqvist
mesh_terms: D000818:Animals; D001673:Biodegradation, Environmental; D001863:Bone Screws; D004548:Elasticity; D004867:Equipment Design; D008334:Mandible / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D008852:Microradiography; D010012:Osteogenesis; D010027:Osteotomy / Q000295:instrumentation* / Q000379:methods*; D010865:Pilot Projects; D011091:Polyesters / Q000737:chemistry*; D012756:Sheep; D013499:Surface Properties; D013997:Time Factors; D014945:Wound Healing
chemical_list: D011091:Polyesters; C033616:poly(lactide)