title: Two populations of cells that express preprocholecystokinin mRNA in ventral periaqueductal grey.
abstract: Cells expressing preprocholecystokinin (CCK) mRNA in the rat midbrain periaqueductal grey area and Edinger-Westphal nucleus were analysed using in situ hybridization combined with liquid emulsion techniques. Semi-quantitative image analysis revealed that there were two populations of cells which expressed CCK mRNA. The first group of cells were large and heavily labelled and were confined to the Edinger-Westphal nucleus. The second group of cells were small and lightly labelled and were found scattered throughout ventral parts of the anterior periaqueductal grey.
authors.affiliation: Division of Biochemistry, UMDS, University of London, UK.
authors.forename: M
authors.initials: M
authors.lastname: Rattray
authors.forename: D
authors.initials: D
authors.lastname: Savery
authors.forename: G
authors.initials: G
authors.lastname: Wotherspoon
authors.forename: J V
authors.initials: JV
authors.lastname: Priestley
authors.forename: G S
authors.initials: GS
authors.lastname: Smith
mesh_terms: D000818:Animals; D001483:Base Sequence; D002766:Cholecystokinin / Q000096:biosynthesis*; D015870:Gene Expression; D017403:In Situ Hybridization; D008297:Male; D008969:Molecular Sequence Data; D010487:Periaqueductal Gray / Q000166:cytology* / Q000378:metabolism; D011498:Protein Precursors / Q000096:biosynthesis*; D012333:RNA, Messenger / Q000096:biosynthesis*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D011498:Protein Precursors; D012333:RNA, Messenger; C042082:preprocholecystokinin; D002766:Cholecystokinin