Complement activation by lipopolysaccharides purified from gram-negative bacteria isolated from infected root canals.
The purpose of the present study was to investigate the complement activation by lipopolysaccharides purified from Porphyromonas (Bacteroides) endodontalis, Veillonella parvula, and Fusobacterium nucleatum isolated from infected root canals. The rate of consumption of the C3T component of the complement increased remarkably when lipopolysaccharides of more than 10 micrograms were added.
Horiba
N
N
Department of Endodontics, School of Dentistry, Aichi-Gakuin University, Nagoya, Japan.
Maekawa
Y
Y
Yamauchi
Y
Y
Ito
M
M
Matsumoto
T
T
Nakamura
H
H
D001439:Bacteroides / Q000276:immunology; D003167:Complement Activation / Q000276:immunology*; D003176:Complement C3 / Q000032:analysis; D015941:Complement Hemolytic Activity Assay; D016967:Fusobacterium nucleatum / Q000276:immunology; D006090:Gram-Negative Bacteria / Q000276:immunology*; D006801:Humans; D008070:Lipopolysaccharides / Q000276:immunology*; D010485:Periapical Periodontitis / Q000276:immunology* / Q000382:microbiology*; D013053:Spectrophotometry; D014678:Veillonella / Q000276:immunology
D003176:Complement C3; D008070:Lipopolysaccharides