title: T cell recognition of hepatitis B envelope proteins.
abstract: We have studied the T-cell processing pathways of Hepatitis B antigens and the role of specific B lymphocytes. It could be shown that some form of processing by specific B cells is required for class I CTLs. This mechanism differs from class II endosomal processing. In addition, it could be shown that lysis of HBsAg-specific B cells may be partly responsible for chronic HBV carrier states.
authors.affiliation: Fondazione Andrea Cesalpino, I Clinica Medica, Università La Sapienza, Roma, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Barnaba
authors.forename: A
authors.initials: A
authors.lastname: Franco
authors.forename: M
authors.initials: M
authors.lastname: Paroli
authors.forename: R
authors.initials: R
authors.lastname: Benvenuto
authors.forename: I
authors.initials: I
authors.lastname: Santilio
authors.forename: F
authors.initials: F
authors.lastname: Balsano
mesh_terms: D001402:B-Lymphocytes / Q000276:immunology; D002353:Carrier State / Q000276:immunology; D006509:Hepatitis B / Q000276:immunology*; D006514:Hepatitis B Surface Antigens / Q000276:immunology; D006801:Humans; D013601:T-Lymphocytes / Q000276:immunology*; D014759:Viral Envelope Proteins / Q000276:immunology*
chemical_list: D006514:Hepatitis B Surface Antigens; D014759:Viral Envelope Proteins