title: Scleritis as an initial manifestation of choroidal malignant melanoma.
abstract: OBJECTIVE
  The purpose of this article is to present the unusual circumstances in which malignant melanoma of the choroid can masquerade as scleritis, thus confounding its diagnosis.
  
  
  METHODS
  Three cases of plaque-like malignant melanomas of the choroid are reported that, on initial examination, had features of scleritis. The events leading to their eventual correct diagnosis also are presented.
  
  
  RESULTS
  In each case, there was ocular pain, blurred vision, anterior chamber and/or vitreous cavity cellular reaction, and an exudative retinal detachment associated with an ill-defined, relatively flat variably pigmented choroidal mass. In all three cases, the inflammatory component responded promptly to corticosteroid treatment and was accompanied by visual improvement. In two eyes, shrinkage of the choroidal mass accompanied the corticosteroid treatment, lending support to a working diagnosis of scleritis. By demonstrating expansion of the choroidal masses, examination of sequential fundus photographs influenced the decision to enucleate the eyes for presumed malignant choroidal melanoma.
  
  
  CONCLUSIONS
  Clinicians should be alert to the circumstances in which malignant melanomas of the choroid can masquerade as scleritis. Careful evaluation by ophthalmoscopy, ultrasonography, fundus photography, and subsequent sequential examination is necessary to arrive at the correct diagnosis.
authors.affiliation: Department of Ophthalmology, Mayo Clinic, Rochester, MN 55905.
authors.forename: E Y
authors.initials: EY
authors.lastname: Yap
authors.forename: D M
authors.initials: DM
authors.lastname: Robertson
authors.forename: H
authors.initials: H
authors.lastname: Buettner
mesh_terms: D000328:Adult; D002830:Choroid Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D015353:Eye Enucleation; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D012163:Retinal Detachment / Q000175:diagnosis; D015423:Scleritis / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D014786:Vision Disorders / Q000175:diagnosis
chemical_list: D011239:Prednisolone