title: Systemic therapy of breast cancer in early and advanced disease.
abstract: Despite substantial advances in breast cancer treatment, mortality from this disease remains high. While adjuvant chemo-hormonal therapy has significantly improved survival, breast cancer still claims the lives of more than 45,000 American women each year. This article is a brief review of various modalities used in the management of breast cancer, including adjuvant and neoadjuvant therapy, treatment for advanced disease, dose intensification, and autologous bone marrow transplantation.
authors.affiliation: College of Osteopathic Medicine, Michigan State University, East Lansing.
authors.forename: B
authors.initials: B
authors.lastname: Layhe
authors.forename: N
authors.initials: N
authors.lastname: Dimitrov
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007155:Immunologic Factors / Q000008:administration & dosage / Q000627:therapeutic use; D008408:Mastectomy / Q000592:standards; D009367:Neoplasm Staging; D015996:Survival Rate
chemical_list: D007155:Immunologic Factors