title: [A neuromorphological analysis of the motor area of the cerebral cortex in rat pups subjected to prenatal exposure to normal and pathological blood serum].
abstract: Morphological quantitative and qualitative analysis of the pyramidal neurones in the motor cortex of rat puppies after administration of the blood serum from human donors with central motor disorders reveals the dependence of the quality and quantity of neurones from the effect of corresponding blood sera. Pathologic blood serum decreases the number and induces degradation of dendritic organization of the pyramidal neurones. The effect of the blood sera on quantitative and qualitative properties of the pyramidal neurones in rat puppies depends on the age of donor infants with central motor disorders. Blood serum from newborn babies with motor dysfunctions significantly decreases the number of labeled pyramidal neurones and results in degradation of dendritic organization, whereas sera from 11-13-year infants only insignificantly affect these characteristics.
authors.forename: G P
authors.initials: GP
authors.lastname: Obukhova
authors.forename: S G
authors.initials: SG
authors.lastname: Seliverova
authors.forename: E I
authors.initials: EI
authors.lastname: Varlinskaia
authors.forename: T V
authors.initials: TV
authors.lastname: Avaliani
authors.forename: N S
authors.initials: NS
authors.lastname: Abdaladze
authors.forename: V A
authors.initials: VA
authors.lastname: Ter-Karapenian
authors.forename: O V
authors.initials: OV
authors.lastname: Bogdanov
mesh_terms: D000293:Adolescent; D000818:Animals; D001790:Blood Physiological Phenomena; D002547:Cerebral Palsy / Q000097:blood; D002648:Child; D003712:Dendrites / Q000187:drug effects / Q000648:ultrastructure; D004281:Docosahexaenoic Acids / Q000494:pharmacology; D015118:Eicosapentaenoic Acid / Q000494:pharmacology; D004576:Electromyography / Q000187:drug effects; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009044:Motor Cortex / Q000187:drug effects* / Q000648:ultrastructure; D009474:Neurons / Q000187:drug effects* / Q000648:ultrastructure; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D014165:Transfer Factor / Q000494:pharmacology
chemical_list: D014165:Transfer Factor; D004281:Docosahexaenoic Acids; D015118:Eicosapentaenoic Acid
vernacular_title: Neĭromorfologicheskiĭ analiz motornoĭ oblasti kory mozga krysiat, podvergshikhsia prenatal'nomu vozdeĭstviiu normal'noĭ i patologicheskoĭ syvorotki krovi.