Some indications for the gynaecological use of budesonide (Apulein).
Budesonide-containing Apulein ointment has been used for the treatment of 29 women suffering from vulvitis, pruritus vulvae caused by vaginal discharge, gestational inflamed hemorrhoid, hymenitis, and late postoperative suture inflammation. The ointment rapidly and completely controlled local infiltration and the accompanying subjective complaints. It did not cause local alteration, the consistency of the ointment met the requirements and it did not disturb the patients' making their toilet. According to the author's opinion the product is a potent antiphlogistic which proved to be a valuable adjuvant to target specific treatment of inflammatory processes of the external female genital organs and perianal regions.
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Department of Obstetrics and Gynaecology, Schöpf-Mérei Agost Hospital, Budapest.
D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D019819:Budesonide; D005260:Female; D005831:Genital Diseases, Female / Q000175:diagnosis / Q000188:drug therapy*; D005938:Glucocorticoids; D006801:Humans; D008875:Middle Aged; D009824:Ointments; D011282:Pregnenediones / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D013997:Time Factors
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D009824:Ointments; D011282:Pregnenediones; D019819:Budesonide