title: Sudden death associated with aortitis and fibrosclerosing disease of the conduction system.
abstract: Aortitis is known to complicate a number of autoimmune diseases and syphilis. In most patients with autoimmune disease, arthritis is the initial presentation followed by aortic insufficiency. We report two cases of ostensibly healthy, middle-aged men in whom the initial manifestation of aortitis was sudden death. In each patient, there was extension of inflammation from the aorta into the atrioventricular node. These cases emphasize the importance of examining the conducting system in cases of sudden death associated with aortitis and no grossly evident cause of death. To our knowledge, this is the first report of aortitis presenting as sudden death.
authors.affiliation: Blodgett Memorial Medical Center, Grand Rapids, MI 49506.
authors.forename: S D
authors.initials: SD
authors.lastname: Cohle
authors.forename: L S
authors.initials: LS
authors.lastname: Harris
authors.forename: J T
authors.initials: JT
authors.lastname: Lie
mesh_terms: D001025:Aortitis / Q000150:complications* / Q000401:mortality / Q000473:pathology; D001283:Atrioventricular Node / Q000473:pathology*; D002423:Cause of Death; D005355:Fibrosis; D006327:Heart Block / Q000209:etiology* / Q000401:mortality / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged