title: [Effect of pH on preferential antibacterial-activity of ethylenediaminetetraacetic acid (EDTA)].
abstract: Ethylenediaminetetraacetic acid (EDTA), a chelating agent, was examined for the antibacterial activity against 15 species of bacteria by treating with a 10mM solution at pH adjusted to 5.0, 7.0 or 9.0. All bacterial species tested were classified into three groups; tentatively named the pH5 EDTA-sensitive group comprising Vibrio cholerae and Staphylococcus aureus, the pH9 EDTA-sensitive group comprising Escherichia coli and Pseudomonas aeruginosa and the EDTA-nonsensitive group comprising Proteus mirabilis. The EDTA-sensitivity grouping may be used as a tool for preferential decontamination of certain bacteria in live edible fishes, although further experiments are needed to characterize more strains and also species of bacteria.
authors.affiliation: Center for Inspection of Imported Foods and Infectious Diseases, Yokohama Quarantine Station, Ministry of Health and Welfare, Kanagawa, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Kida
authors.forename: S
authors.initials: S
authors.lastname: Suzuki
authors.forename: T
authors.initials: T
authors.lastname: Yamanaka
authors.forename: K
authors.initials: K
authors.lastname: Furuyama
authors.forename: F
authors.initials: F
authors.lastname: Taguchi
mesh_terms: D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D015169:Colony Count, Microbial; D004492:Edetic Acid / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration
chemical_list: D004492:Edetic Acid