Eosinophilic fasciitis associated with L-tryptophan ingestion.
OBJECTIVE
To present the first case of eosinophilic fasciitis associated with L-tryptophan ingestion.


METHODS
A 23-year-old Australian man developed myalgia and weakness, and later the clinical features of eosinophilic fasciitis, while taking L-tryptophan.


RESULTS
The amino acid supplementation was discontinued and he was treated with prednisone (30 mg/day) for six weeks with significant improvement.


CONCLUSIONS
In sclerodermatous skin diseases, such as eosinophilic fasciitis, the possibility of ingestion of tryptophan-containing products should be considered.
Grigoris
I
I
Skin and Cancer Foundation, Westmead, NSW.
de Launey
W
W
Jevtic
A P
AP
D000328:Adult; D004802:Eosinophilia / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D005208:Fasciitis / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D014364:Tryptophan / Q000009:adverse effects*
D014364:Tryptophan; D011241:Prednisone