title: The role of the rat submandibular gland in the excretion of bis (tributyltin) oxide: electron microscopy, X-ray microanalysis and atomic absorption analysis.
abstract: The role of the submandibular glands in the excretion of parenterally administered bis (tributyltin) oxide (TBTO) was studied. Fine structural alterations of the submandibular glands were observed with an electron microscope. Accumulation sites of TBTO were determined with an X-ray microanalyzer and tin concentrations in saliva and blood were measured by atomic absorption spectrophotometry.
authors.affiliation: Department of Anatomy, University of Occupational and Environmental Health, School of Medicine, Kitakyushu, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Yoshizuka
authors.forename: K
authors.initials: K
authors.lastname: Hara
authors.forename: N
authors.initials: N
authors.lastname: Nagata
authors.forename: Y
authors.initials: Y
authors.lastname: Doi
authors.forename: M
authors.initials: M
authors.lastname: Yokoyama
authors.forename: T
authors.initials: T
authors.lastname: Sagara
authors.forename: S
authors.initials: S
authors.lastname: Fujimoto
mesh_terms: D000818:Animals; D004577:Electron Probe Microanalysis; D008297:Male; D008854:Microscopy, Electron; D051381:Rats; D017208:Rats, Wistar; D012463:Saliva / Q000737:chemistry; D013054:Spectrophotometry, Atomic; D013363:Submandibular Gland / Q000187:drug effects / Q000378:metabolism* / Q000648:ultrastructure; D014001:Tin / Q000032:analysis / Q000097:blood; D014220:Trialkyltin Compounds / Q000378:metabolism* / Q000494:pharmacology
chemical_list: D014220:Trialkyltin Compounds; C005961:bis(tri-n-butyltin)oxide; D014001:Tin