title: MRI evaluation of amyloid myopathy.
abstract: Amyloid myopathy is a rare complication of primary amyloidosis. The magnetic resonance imaging (MRI) features of two patients with amyloid myopathy were studied. Slight prolongation of muscle T1 and T2 relaxation times was evident but the striking abnormality was marked reticulation of the subcutaneous fat. The clinical findings of indurated extremities far exceeds the minimal signal intensity alteration seen in the muscles. The MR appearance of amyloid myopathy differs from that of other neuromuscular conditions in the minimal changes found in muscle, but the striking abnormality seen in subcutaneous fat makes it distinct from many neuromuscular conditions.
authors.affiliation: Department of Radiology, University of Texas Southwestern Medical Center, Dallas.
authors.forename: J P
authors.initials: JP
authors.lastname: Metzler
authors.forename: J L
authors.initials: JL
authors.lastname: Fleckenstein
authors.forename: C L
authors.initials: CL
authors.lastname: White
authors.forename: R G
authors.initials: RG
authors.lastname: Haller
authors.forename: E P
authors.initials: EP
authors.lastname: Frenkel
authors.forename: R G
authors.initials: RG
authors.lastname: Greenlee
mesh_terms: D000682:Amyloid; D000686:Amyloidosis / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009135:Muscular Diseases / Q000175:diagnosis* / Q000473:pathology; D017285:Polymyositis / Q000175:diagnosis
chemical_list: D000682:Amyloid