Occupational asthma induced by the fungicide tetrachloroisophthalonitrile.
A 48 year old male farmer had recurrent episodes of dyspnoea, shortness of breath, and wheezing after being in his plastic greenhouse when the fungicide tetrachloroisophthalonitrile had been sprayed. A bronchial provocation test with a control challenge and a patch skin test confirmed that his asthma was induced by tetrachloroisophthalonitrile.
Honda
I
I
First Department of Internal Medicine, Kumamoto University Medical School, Japan.
Kohrogi
H
H
Ando
M
M
Araki
S
S
Ueno
T
T
Futatsuka
M
M
Ueda
A
A
D000382:Agricultural Workers' Diseases / Q000139:chemically induced*; D001249:Asthma / Q000139:chemically induced* / Q000175:diagnosis; D001985:Bronchial Provocation Tests; D005659:Fungicides, Industrial / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009570:Nitriles / Q000009:adverse effects*
D005659:Fungicides, Industrial; D009570:Nitriles; C005806:tetrachloroisophthalonitrile