title: Identification of silicone oil in the retina after intravitreal injection.
abstract: Retinal tissue obtained from 2 eyes that had been injected with silicone oil for 2 years was stained with monoclonal antibodies against macrophages and studied by light and electron microscopy and energy-dispersive x-ray analysis. Both specimens showed areas with a relatively intact architecture as well as parts with loss of normal structure. In both areas, immunostaining showed single intraretinal macrophages. Energy-dispersive x-ray results clearly demonstrated that some of the intracellular and extracellular vacuoles within the retina represented the storage sites of silicone.
authors.affiliation: Department of Ophthalmology, University of Kiel, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Eckardt
authors.forename: U
authors.initials: U
authors.lastname: Nicolai
authors.forename: M
authors.initials: M
authors.lastname: Czank
authors.forename: D
authors.initials: D
authors.lastname: Schmidt
mesh_terms: D000328:Adult; D004577:Electron Probe Microanalysis; D005260:Female; D006801:Humans; D008297:Male; D011183:Postoperative Complications; D012160:Retina / Q000737:chemistry* / Q000648:ultrastructure; D012163:Retinal Detachment / Q000601:surgery; D012827:Silicone Oils / Q000032:analysis*; D014821:Vitrectomy; D014822:Vitreous Body
chemical_list: D012827:Silicone Oils