title: Hemodynamic changes in the dog connected to a dialysis circuit: influence of the body temperature.
abstract: Eighteen sessions in 9 mongrel dogs were carried out to know the hemodynamic effects produced by body temperature variation, when blood passes through a dialysis circuit with a Cuprophan dialyzer, without dialysate contact. The decrease of 2 degrees C in body temperature caused a decrease in heart rate and cardiac index (-8.6 and -17.6%, respectively) without significant changes in blood pressure. The increase of 2 degrees C in body temperature increased the heart rate, the cardiac index and the first derivative of ventricular pressure (+14.8, +17.3 and +27.8%, respectively) with a decrease of 13.6% in the systemic vascular resistance. Blood pressure did not change significantly. We conclude that the dog maintains the hemodynamic stability by two different mechanisms: when body temperature rises, by increasing the cardiac index; when body temperature decreases, by increasing the systemic vascular resistance.
authors.affiliation: Servicio de Nefrología, Hospital Ramón y Cajal, Madrid, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Orofino
authors.forename: C
authors.initials: C
authors.lastname: Quereda
authors.forename: R
authors.initials: R
authors.lastname: Marcén
authors.forename: J J
authors.initials: JJ
authors.lastname: Villafruela
authors.forename: J
authors.initials: J
authors.lastname: Sabater
authors.forename: P
authors.initials: P
authors.lastname: Jorge
authors.forename: L
authors.initials: L
authors.lastname: Landin
authors.forename: J
authors.initials: J
authors.lastname: Ortuño
mesh_terms: D000818:Animals; D001794:Blood Pressure; D001831:Body Temperature; D002302:Cardiac Output; D004285:Dogs; D006339:Heart Rate; D006439:Hemodynamics; D007958:Leukocyte Count; D006435:Renal Dialysis; D014655:Vascular Resistance