title: Thermal sensitivity and effect of temperature acclimation on ocular serotonin N-acetyltransferase activity in Rana perezi.
abstract: The thermal sensitivity and the response to thermal acclimation of the serotonin N-acetyltransferase (NAT) activity in frog ocular tissue were studied. The ocular NAT shows a positive thermal modulation for both cosubstrates (tryptamine and acetyl-CoA). The higher NAT activity in the cold-acclimated group (4 degrees C) with respect to the warm-acclimated one (24 degrees C) implies a partial thermal compensation of the enzyme. The present results suggest that frog ocular NAT response to temperature entails a modulation of thermal sensitivity of the enzyme rather than changes in enzyme concentration.
authors.affiliation: Departamento de Biología Animal II, Fisiología Animal, Facultad de Biología, Universidad Complutense, Madrid, Spain.
authors.forename: A L
authors.initials: AL
authors.lastname: Alonso-Gómez
authors.forename: M
authors.initials: M
authors.lastname: Alonso-Bedate
authors.forename: M J
authors.initials: MJ
authors.lastname: Delgado
mesh_terms: D000064:Acclimatization / Q000502:physiology*; D000105:Acetyl Coenzyme A / Q000378:metabolism; D000818:Animals; D001191:Arylamine N-Acetyltransferase / Q000378:metabolism*; D005123:Eye / Q000201:enzymology*; D006358:Hot Temperature; D007700:Kinetics; D011898:Ranidae; D012160:Retina / Q000201:enzymology; D014363:Tryptamines / Q000378:metabolism
chemical_list: D014363:Tryptamines; D000105:Acetyl Coenzyme A; D001191:Arylamine N-Acetyltransferase