[Mouse serum inhibition of cytotoxicity of goat antibodies against mouse thymocytes].
It is shown that the serum of Balb/c, C57Bl/6 and F1(C57Bl/6 x CBA) mice inhibits cytotoxicity of goat antithymocyte antibodies. The addition of the serum into the incubation medium increases the proportion of alive cells from -5% up to 95%. Cytotoxicity was also inhibited by the globulin fraction of the mice serum. It is suggested that normal mice serum contains factors which block cytotoxicity of antibodies against antigen host determinants.
Donenko
F V
FV
Kabieva
A O
AO
Volkov
Iu T
IuT
Moroz
L V
LV
D000818:Animals; D000906:Antibodies / Q000032:analysis; D002478:Cells, Cultured; D003601:Cytotoxicity Tests, Immunologic; D003602:Cytotoxicity, Immunologic; D006041:Goats; D007136:Immunoglobulins / Q000032:analysis; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D013601:T-Lymphocytes / Q000276:immunology*
D000906:Antibodies; D007136:Immunoglobulins
Ingibirovanie tsitotoksichnosti koz'ikh antitel protiv timotsitov myshi syvorotkoĭ mysheĭ.