The mutant mitochondrial genes in mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) were selectively amplified through generations.
Kobayashi
Y
Y
Department of Pediatrics, Jichi Medical School, Tochigi, Japan.
Ichihashi
K
K
Ohta
S
S
Nihei
K
K
Kagawa
Y
Y
Yanagisawa
M
M
Momoi
M Y
MY
D000328:Adult; D001345:Autoradiography; D001483:Base Sequence; D003001:Cloning, Molecular; D004272:DNA, Mitochondrial / Q000032:analysis / Q000235:genetics; D004591:Electrophoresis, Polyacrylamide Gel; D005784:Gene Amplification; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism; D017241:MELAS Syndrome / Q000235:genetics*; D008928:Mitochondria / Q000378:metabolism*; D008969:Molecular Sequence Data
D004272:DNA, Mitochondrial