title: [The motor activity of the chick embryo amnion in the late stages of development. The role of serotonin and noradrenaline].
abstract: Experiments with 13- to 19-day-old chicken embryos maintained at 37 degrees C were conducted using direct registration of embryonic movements and amnion pulsation. It is shown that in the non-innervated and lacking blood vessels non-striated-muscled amnion, motoric activity could be observed nearly up to the end of the embryonic development, not only during 5 to 14 days old interval as it was supposed earlier. In accordance with our previous results indicating important role of biogenic amines (serotonin and noradrenaline) in the regulation of motoric activity of the chicken embryo amnion at earlier and middle ages, this study provides some evidences of the humoral regulatory mechanism even at later embryonic stages. After being injected into amniotic fluid of older embryos, the serotonin stimulates and noradrenaline inhibits amnion motoric activity (the both are taken at final concentration of 10(-7) to 10(-6) M). Serotonin's receptors blocator, the cyprogeptadin, suppress while beta-adrenoreceptors' blocator, the propranolol, activates intact amnion motorics ( both are taken at final concentration of 10(-7) to 10(-5) M).
authors.forename: M B
authors.initials: MB
authors.lastname: Nechaeva
authors.forename: T M
authors.initials: TM
authors.lastname: Turpaev
mesh_terms: D000650:Amnion / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D002642:Chick Embryo; D003533:Cyproheptadine / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D005324:Fetal Movement / Q000187:drug effects / Q000502:physiology*; D009068:Movement / Q000187:drug effects / Q000502:physiology; D009638:Norepinephrine / Q000494:pharmacology* / Q000502:physiology; D011433:Propranolol / Q000494:pharmacology; D012701:Serotonin / Q000494:pharmacology* / Q000502:physiology; D013997:Time Factors
chemical_list: D003533:Cyproheptadine; D012701:Serotonin; D011433:Propranolol; D009638:Norepinephrine
vernacular_title: Dvigatel'naia aktivnost' amniona kurinogo zarodysha pozdnykh stadiĭ razvitiia. Rol' serotonina i noradrenalina.