[The results of a retrospective examination of patients with acute rheumatic fever].
The authors describe the results obtained during retrospective examinations of 45 subjects who suffered from acute rheumatic fever 10-14 years before. Of these, 19 subjects were treated with prednisolone in the acute disease period, 16 with indomethacin, and 8 subjects with voltaren. The examinations were mostly randomized (30 subjects); no differences in the anti-inflammatory effect were discovered. Heart disease was found in 9 persons (20%). Of these, 6 were treated with prednisolone, 2 with indomethacin, and 1 with voltaren. The disease relapses were recorded in 4 of them, the signs of valvulitis in the past were shown only by 2 persons (echocardiographically). 12 persons (27%) had mitral valve prolapse which had not been diagnosed on the first admission to the hospital, with any clinical signs of hypermotility lacking. In 18 persons (40%) having no valve lesions (disease, prolapse), an x-ray examination revealed a slight increase of the heart size, estimated as a manifestation of postmyocardial cardiosclerosis. Thus, it has been shown that modern anti-inflammatory therapy does not prevent the development of heart disease. Apparently, its onset is related to specific proneness in some of the patients.
Dzhuzenova
B S
BS
Kotel'nikova
G P
GP
Nesterova
N I
NI
Nasonova
V A
VA
D005500:Follow-Up Studies; D006801:Humans; D012008:Recurrence; D012189:Retrospective Studies; D012213:Rheumatic Fever / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D012214:Rheumatic Heart Disease / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology; D012426:Russia / Q000453:epidemiology; D011795:Surveys and Questionnaires
Rezul'taty retrospektivnogo obsledovaniia bol'nykh ostroĭ revmaticheskoĭ likhoradkoĭ.