A literature review of dermatotoxicity.
Dermatotoxicity is the skin's response to chemical substances that produce damage. Penetration of the chemical to the various skin layers is important and may result in irritation, allergic contact dermatitis, contact urticaria, one of various forms of photosensitization, or other cutaneous reactions. The testing of new products or industrial chemicals for potential dermatotoxicity is an important process in protecting the public's health.
Ali
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Comparative Toxicology Laboratories, College of Veterinary Medicine, Kansas State University, Manhattan 66506-5606.
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D000042:Absorption; D000818:Animals; D003877:Dermatitis, Contact / Q000209:etiology*; D017453:Dermatitis, Irritant / Q000209:etiology*; D006168:Guinea Pigs; D015386:Hazardous Substances / Q000009:adverse effects* / Q000032:analysis / Q000493:pharmacokinetics; D006801:Humans; D051379:Mice; D010787:Photosensitivity Disorders / Q000139:chemically induced*; D011817:Rabbits; D012867:Skin / Q000033:anatomy & histology / Q000187:drug effects* / Q000378:metabolism; D012879:Skin Physiological Phenomena; D012882:Skin Tests / Q000379:methods; D014581:Urticaria / Q000139:chemically induced*
D015386:Hazardous Substances