title: Measurement, analysis, and modelling of the caloric response. 1. A descriptive mathematical model of the caloric response over time.
abstract: A mathematical model for describing the caloric response over time offers many important advantages over the commercially-available qualitatively-fitted curves that are now used by the clinician for evaluating caloric results. In this report advances in the development of a nonlinear least-squares mathematical model are discussed and the roles and derivations of fitting parameters and curve-derived indices are outlined. This model provides a rigorous and objective description of the caloric response in its entirety with four continuous parameters. These fitting parameters make it possible to 1) describe individual caloric responses precisely and uniquely, 2) compare pairs of individual caloric responses or groups of caloric responses statistically, 3) extract information not previously available, 4) quantify variability within the caloric response, and 5) model physical properties of the caloric stimulus and physiological variables affecting the caloric response. Results from this model are compared with the results from our earlier models and with traditional multiparameter caloric results.
authors.affiliation: Department of Otolaryngology-Head & Neck Surgery, John Hopkins University School of Medicine, Baltimore, MD.
authors.forename: C
authors.initials: C
authors.lastname: Formby
authors.forename: R L
authors.initials: RL
authors.lastname: Carter
authors.forename: C A
authors.initials: CA
authors.lastname: Hansen
authors.forename: L A
authors.initials: LA
authors.lastname: Kuntz
mesh_terms: D002150:Caloric Tests; D006801:Humans; D008433:Mathematics; D008954:Models, Biological; D013997:Time Factors