Novel coagglutination method for serotyping group B streptococci.
A group G streptococcal strain was coated with antibody against six different serotypes (Ia, Ib, II, III, IV, and V) of group B streptococci. The coagglutination patterns of 114 strains of group B streptococci were compared with the serotypes determined after immunoprecipitation. The specificity of the method was 100% and the sensitivity 97%. It was used for the typing of 89 invasive and 101 colonizing isolates. The new method is swift, specific, and highly sensitive. It consumes only minute amounts of antibody.
Håkansson
S
S
Department of Pediatrics, University of Umeå, Sweden.
Burman
L G
LG
Henrichsen
J
J
Holm
S E
SE
D000372:Agglutination Tests / Q000379:methods / Q000706:statistics & numerical data; D005069:Evaluation Studies as Topic; D006801:Humans; D012680:Sensitivity and Specificity; D012703:Serotyping / Q000379:methods* / Q000706:statistics & numerical data; D013292:Streptococcus agalactiae / Q000145:classification*