[Effects of valerian root oil, borneol, isoborneol, bornyl acetate and isobornyl acetate on the motility of laboratory animals (mice) after inhalation].
The aromatherapeutical use of commercial valerian root oil (Chinese origin) and of pure fragrance compounds--borneol, isoborneol, bornyl acetate (main constituent of the proved valerian root oil) and isobornyl acetate--as potentially drugs with sedative effects after inhalation was investigated in an animal experiment (mice). In additional analyses the mice were treated i.p. by caffeine and distinct sedative effects were observed only by inhalation of the cited substances.
Buchbauer
G
G
Institut für Pharmazeutische Chemie, Universität Wien.
Jäger
W
W
Jirovetz
L
L
Meyer
F
F
Dietrich
H
H
D000818:Animals; D002110:Caffeine / Q000037:antagonists & inhibitors / Q000494:pharmacology; D002849:Chromatography, Gas; D008401:Gas Chromatography-Mass Spectrometry; D006993:Hypnotics and Sedatives / Q000494:pharmacology; D051379:Mice; D009043:Motor Activity / Q000187:drug effects*; D010938:Plant Oils / Q000737:chemistry / Q000494:pharmacology*; D010946:Plants, Medicinal; D014632:Valerian / Q000737:chemistry*
D006993:Hypnotics and Sedatives; D010938:Plant Oils; D002110:Caffeine
Wirkungen von Baldrianöl, Borneol, Isoborneol, Bornylacetat und Isobornylacetat auf die Motilität von Versuchstieren (Mäusen) nach Inhalation.