Testing meningeal strains of Streptococcus suis to detect M protein genes.
Previous reports have suggested that the surface proteins found in meningeal strains of Streptococcus suis might be similar to the M protein of group A streptococci. Fifty-five strains of S suis, including human and swine meningeal and pneumonic isolates, were tested for M protein genes by DNA probes representing the constant domain of the 3' end of the group A, M protein gene. None of the S suis strains examined was positive, indicating that these organisms either lack M protein genes or harbour different genes, not expressing the constant domains of protein M from group A.
Mogollon
J D
JD
Department of Clinical and Populations Sciences, College of Veterinary Medicine, University of Minnesota, St Paul 55108.
Pijoan
C
C
Murtaugh
M P
MP
Cleary
P P
PP
Collins
J E
JE
D000818:Animals; D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins / Q000235:genetics*; D002352:Carrier Proteins; D005798:Genes, Bacterial / Q000235:genetics*; D006801:Humans; D016920:Meningitis, Bacterial / Q000382:microbiology / Q000662:veterinary; D009693:Nucleic Acid Hybridization; D013290:Streptococcal Infections / Q000382:microbiology / Q000662:veterinary; D017011:Streptococcus suis / Q000235:genetics* / Q000302:isolation & purification; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology
D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D002352:Carrier Proteins; C014689:streptococcal M protein