title: The effect of strontium chloride hexahydrate dentifrices on plaque accumulation and gingival inflammation.
abstract: 2 strontium chloride hexahydrate-containing dentifrices (SCH), similar except for their respective abrasive systems, diatomaceous earth or silica-based, were compared for their effects on plaque accumulation and gingival inflammation as part of a 2-month randomised double-blind parallel clinical study. No attempt was made to change the patients' oral hygiene prior to participation in the study. Plaque was assessed using the Silness & Löe index and the gingival condition by the Löe & Silness index GI. There was a slight and non-significant increase in plaque accumulation at 2 weeks from baseline, but relatively negligible change thereafter, the effect being identical in both groups. Similarly, the gingival condition showed a slight index change from baseline, although it tended to be slightly higher in the diatomaceous earth group. The results do not support the conclusions of previous studies which indicated that SCH dentifrices increased plaque accumulation. Neither plaque accumulation nor gingival condition significantly changed from baseline levels during the course of the study.
authors.affiliation: Department of Periodontology, University of London, UK.
authors.forename: D G
authors.initials: DG
authors.lastname: Gillam
authors.forename: H N
authors.initials: HN
authors.lastname: Newman
authors.forename: J S
authors.initials: JS
authors.lastname: Bulman
mesh_terms: D000328:Adult; D003773:Dental Plaque / Q000188:drug therapy*; D003774:Dental Plaque Index; D003807:Dentin Sensitivity / Q000188:drug therapy; D007692:Diatomaceous Earth / Q000627:therapeutic use; D004311:Double-Blind Method; D005260:Female; D005891:Gingivitis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013324:Strontium / Q000627:therapeutic use*; D014100:Toothpastes / Q000592:standards / Q000627:therapeutic use*
chemical_list: D014100:Toothpastes; D007692:Diatomaceous Earth; C025700:strontium chloride; D013324:Strontium