[The action of carnitine-series preparations in experimental alloxan diabetes mellitus].
The study was undertaken to examine the effects of l-carnitine and acetyl-l-carnitine in rats and mice with experimental alloxan diabetes. The findings suggest that acetyl-l-carnitine is more effective against diabetes in increasing glucose tolerance, restoring the impaired response of glucagon to glucose, showing glycogen-sparing action than is l-carnitine.
Kim
E K
EK
Trevisani
C
C
Trevisani
M
M
D000108:Acetylcarnitine / Q000627:therapeutic use*; D000818:Animals; D002331:Carnitine / Q000627:therapeutic use*; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy* / Q000378:metabolism; D004353:Drug Evaluation, Preclinical; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007333:Insulin Resistance; D008297:Male; D051379:Mice; D051381:Rats
D007004:Hypoglycemic Agents; D000108:Acetylcarnitine; D002331:Carnitine
Deĭstvie preparatov karnitinovogo riada pri éksperimental'nom alloksanovom sakharnom diabete.