L-tryptophan ingestion does not induce progressive systemic sclerosis (scleroderma).
A retrospective analysis of 153 patients suffering from progressive systemic sclerosis failed to show any correlation between either onset or worsening of the disease and L-tryptophan ingestion. Only one woman developed typical acrosclerosis without signs of the eosinophilia-myalgia syndrome during exposure to the drug.
Mensing
H
H
Department of Dermatology, University of Hamburg, FRG.
D005260:Female; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies; D012595:Scleroderma, Systemic / Q000139:chemically induced*; D014364:Tryptophan / Q000009:adverse effects*
D014364:Tryptophan