[Assay of micronuclei in binucleated T-lymphocytes. Analysis of the distribution and variation factors in a population of 100 subjects].
The authors analysed micronuclei levels distribution in lymphocytes of 100 non occupationally exposed subjects and studied the effect of age, sex and smoking of donors on the distribution. Results showed that micronucleated cells were distributed according to a normal distribution (average = 9.5 +/- 4 micronucleated cells in 1,000 binucleated lymphocytes). Age and sex of donors had no effect on the distribution but, concerning smoking, the results showed that micronuclei levels were correlated to the number of cigarettes daily smoked.
Di Giorgio
C
C
Laboratoire de biogénotoxicologie, faculté de médecine, Marseille, France.
Botta
A
A
De Meo
M P
MP
Laget
M
M
Dumenil
G
G
D000328:Adult; D000367:Age Factors; D000704:Analysis of Variance; D002467:Cell Nucleus; D005260:Female; D006801:Humans; D008297:Male; D015162:Micronucleus Tests; D008875:Middle Aged; D012737:Sex Factors; D012907:Smoking / Q000453:epidemiology / Q000473:pathology; D013601:T-Lymphocytes / Q000166:cytology*
Le test de numération des micronoyaux dans les lymphocytes T binucléés. Analyse de la répartition et des facteurs de variation sur une population de 100 sujets.