Glycoconjugates as positive and negative modulators of embryo implantation.
A variety of studies indicate that complex glycoproteins participate in or modulate adhesive interactions occurring during embryo implantation. In particular, proteoglycans and proteins that bind proteoglycans are involved at multiple stages of this process. Identification of these binding proteins and the molecular controls over glycoconjugate expression are required to develop a comprehensive understanding of the implantation process.
Carson
D D
DD
Department of Biochemistry and Molecular Biology, University of Texas M. D. Anderson Cancer Center, Houston 77030.
Jacobs
A L
AL
Julian
J
J
Rohde
L H
LH
Valdizan
M C
MC
D000818:Animals; D011508:Chondroitin Sulfate Proteoglycans / Q000502:physiology; D010064:Embryo Implantation / Q000502:physiology*; D004847:Epithelial Cells; D004848:Epithelium / Q000502:physiology; D005260:Female; D006001:Glycoconjugates / Q000502:physiology*; D019812:Heparan Sulfate Proteoglycans; D006497:Heparan Sulfate / Q000502:physiology; D006801:Humans; D011247:Pregnancy; D011509:Proteoglycans / Q000502:physiology; D014599:Uterus / Q000166:cytology / Q000502:physiology
D011508:Chondroitin Sulfate Proteoglycans; D006001:Glycoconjugates; D019812:Heparan Sulfate Proteoglycans; D006497:Heparan Sulfate; D011509:Proteoglycans