title: [An assessment of the immunoepidemiological efficacy of a liquid cultured killed vaccine against tick-borne encephalitis virus strain 205 in the Maritime Territory].
abstract: Inactivated vaccine against tick-borne encephalitis (TBE), prepared on the basis of strain 205, is characterized by epidemiological (53%) and immunobiological activity. The appearance of a few TBE cases among the vaccinees is probably due to different maturation rate of immune response to various strains (different specificity of immune response). A suggestion has been made that no inactivated vaccine prepared from a single strain can produce a reliable protective effect because of pronounced heterogeneity of the population of TBE virus.
authors.forename: G N
authors.initials: GN
authors.lastname: Leonova
authors.forename: N B
authors.initials: NB
authors.lastname: Liubimova
authors.forename: G A
authors.initials: GA
authors.lastname: Sergeev
authors.forename: S M
authors.initials: SM
authors.lastname: Muratkina
authors.forename: S P
authors.initials: SP
authors.lastname: Krugliak
authors.forename: A V
authors.initials: AV
authors.lastname: Bobkov
authors.forename: S I
authors.initials: SI
authors.lastname: Bondarenko
authors.forename: G N
authors.initials: GN
authors.lastname: Tutubalina
authors.forename: M M
authors.initials: MM
authors.lastname: Beliaev
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D004341:Drug Evaluation; D004669:Encephalitis Viruses, Tick-Borne / Q000276:immunology*; D004675:Encephalitis, Tick-Borne / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control*; D006801:Humans; D007115:Immunization Schedule; D008889:Military Personnel; D009326:Naval Medicine; D016036:Seroepidemiologic Studies; D012800:Siberia / Q000453:epidemiology; D013997:Time Factors; D015164:Vaccines, Inactivated / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D015164:Vaccines, Inactivated; D014765:Viral Vaccines
vernacular_title: Otsenka immunoépidemiologicheskoĭ éffektivnosti zhidkoĭ kul'tural'noĭ ubitoĭ vaktsiny protiv kleshchevogo éntsefalita shtamm 205 v usloviiakh Primorskogo kraia.