[Comparative study of LpAI lipoparticles, HDL cholesterol and apolipoprotein AI in a control population, in a group of subjects with coronary diseases, and in a group of subjects with angiographically normal coronary vessels].
A new method for directly measuring LpAI lipoparticles containing apolipoprotein AI, but not apolipoprotein AII, is now disponible for laboratories. Concentrations of LpAI were measured in serum from 158 presumably healthy normolipidemic subjects (72 male, 86 female), for the age group 30-60 years. Concentrations of LpAI were also measured in subjects with angiographically defined coronary artery disease (coro+) and without angiographically defined coronary artery disease (coro-). After comparison of the groups, lipoprotein particle LpAI did not appear to be a better discriminative marker than HDL cholesterol or apolipoprotein AI for atherogen risk.
Ardissone
J P
JP
Laboratoire de biochimie, CHU Timone, Marseille, France.
Cohen-Billiemaz
A
A
Heim
M
M
Gulian
J M
JM
Giordanella
J P
JP
Bory
M
M
Charrel
M
M
D000328:Adult; D000368:Aged; D016632:Apolipoprotein A-I / Q000737:chemistry*; D008076:Cholesterol, HDL / Q000097:blood*; D017023:Coronary Angiography; D003327:Coronary Disease / Q000097:blood* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D005779:Immunodiffusion / Q000379:methods; D008297:Male; D008875:Middle Aged
D016632:Apolipoprotein A-I; D008076:Cholesterol, HDL
Etude comparative des lipoparticules LpAI, du cholestérol HDL et de l'apoprotéine AI, dans une population témoin, dans un groupe de sujets coronariens, et dans un groupe de sujets à coronaires angiographiquement normales.