Encystation of Giardia lamblia leads to expression of antigens recognized by antibodies against conserved heat shock proteins.
During in vitro encystation, Giardia lamblia expresses several stage-specific proteins which are recognized in immunoblots by antisera raised against antigens from three different pathogens. The antigens belong to two different families of conserved stress proteins: (i) HSP60 purified from Legionella pneumophila and recombinant HSP60 from Mycobacterium bovis BCG and (ii) recombinant HSP70 from Plasmodium falciparum.
Reiner
D S
DS
Department of Pathology, University of California, San Diego 92103.
Shinnick
T M
TM
Ardeshir
F
F
Gillin
F D
FD
D000818:Animals; D000953:Antigens, Protozoan / Q000032:analysis*; D016829:Giardia lamblia / Q000276:immunology* / Q000502:physiology; D006360:Heat-Shock Proteins / Q000276:immunology*; D007106:Immune Sera / Q000276:immunology*; D011817:Rabbits
D000953:Antigens, Protozoan; D006360:Heat-Shock Proteins; D007106:Immune Sera