title: Simazine toxicosis in sheep.
abstract: A case of simazine toxicosis in sheep was investigated. Affected animals exhibited generalized muscle tremors which progressed to mild tetany followed by collapse of the hind legs. Other signs included a short prancing gait with head tucked in a similar manner to that of a show pony. Death occurred within 2 to 3 d of the appearance of clinical signs. Mild to acute myocardial degeneration was evident; the livers had mild to acute hepatic fatty change. The levels of simazine found in livers varied from less than 0.2 mg/kg to almost 2 mg/kg in the worst affected animals.
authors.affiliation: Chemistry Branch, Biological and Chemical Research Institute, New South Wales, Australia.
authors.forename: W J
authors.initials: WJ
authors.lastname: Allender
authors.forename: J W
authors.initials: JW
authors.lastname: Glastonbury
mesh_terms: D000818:Animals; D009202:Cardiomyopathies / Q000139:chemically induced / Q000401:mortality / Q000473:pathology / Q000662:veterinary*; D056486:Chemical and Drug Induced Liver Injury; D008107:Liver Diseases / Q000401:mortality / Q000473:pathology / Q000662:veterinary*; D012756:Sheep; D012757:Sheep Diseases / Q000139:chemically induced* / Q000401:mortality / Q000473:pathology; D012839:Simazine / Q000009:adverse effects* / Q000032:analysis
chemical_list: D012839:Simazine