[Demonstration of cerebral lateralisation disorder in autistic children: study of auditory reactivity by transcranial pulsed Doppler].
Transcranial Doppler Ultrasonographic recordings of the middle cerebral arteries were performed on children with autistic behavior (AUT), compared to retarded children without autistic behavior (NON-AUT) and normal children (NOR). Blood flow measurements (resistance index) were performed at rest and during auditory stimulations. Compared to NOR and NON-AUT, significant differences of the resistance index were found in AUT on the left side, thus suggesting differences in metabolic mechanisms evoked by auditory stimulations. This result confirms the hypothesis of abnormal development of cerebral lateralization in autism.
Bruneau
N
N
INSERM U316, Explorations fonctionnelles psychopathologiques, CHU Bretonneau, Tours.
Garreau
B
B
Dourneau
M C
MC
Barthélémy
C
C
Pourcelot
L
L
Lelord
G
G
D001321:Autistic Disorder / Q000000981:diagnostic imaging / Q000503:physiopathology*; D001783:Blood Flow Velocity / Q000502:physiology; D002560:Cerebrovascular Circulation / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D004453:Echoencephalography; D005072:Evoked Potentials, Auditory; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008607:Intellectual Disability / Q000503:physiopathology*
Mise en évidence d'un trouble de la latéralisation cérébrale chez l'enfant autistique: étude de la réactivité auditive par Doppler pulsé transcrânien.