A simple method to test condoms for penetration by viruses.
A method by which virus penetration through condoms can be tested with simple, inexpensive equipment is described. The method uses chi X174 bacteriophage as the challenge virus and physiologically relevant pressure. Penetration by 0.1 microliters (or less) of challenge suspension can be readily detected. As examples, latex and natural-membrane condoms were examined.
Lytle
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Division of Life Sciences, Food and Drug Administration, Rockville, Maryland 20857.
Routson
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Cyr
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D010584:Bacteriophage phi X 174 / Q000302:isolation & purification*; D002021:Buffers; D015169:Colony Count, Microbial; D017280:Condoms / Q000592:standards; D008422:Materials Testing / Q000295:instrumentation* / Q000379:methods* / Q000592:standards; D010539:Permeability
D002021:Buffers