[The characteristics of the humoral response to respiratory syncytial viral infection in adult patients with different forms of bronchitis].
The levels of specific IgG and IgM were determined in 72 patients with verified respiratory syncytial (RS) virus infection: 11 patients with acute delayed bronchitis (ADB), 26 with recurring bronchitis (RB) 35 with chronic obstructive bronchitis (ChOB), by indirect enzyme immunoassay; RS virus was detected by direct immunofluorescent technique. The activity of the inflammatory process in the bronchi was shown to depend upon RS infection activity in cases of ChOB and RB. RS infection was observed to be significantly dependent on obstruction and bronchospasms. The specific humoral response was reduced and delayed in ChOB and RB as compared to acute bronchitis. The possibility of long-term persistence of RS virus antigen in chronic and recurring forms of bronchitis was demonstrated.
Krivitskaia
V Z
VZ
Iakovleva
N V
NV
D000208:Acute Disease; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D000917:Antibody Formation; D000918:Antibody Specificity; D000956:Antigens, Viral / Q000032:analysis; D001991:Bronchitis / Q000209:etiology / Q000276:immunology*; D002908:Chronic Disease; D006801:Humans; D012008:Recurrence; D012136:Respiratory Syncytial Viruses / Q000276:immunology*; D010253:Respirovirus Infections / Q000150:complications / Q000276:immunology*
D000914:Antibodies, Viral; D000956:Antigens, Viral
Osobennosti gumoral'nogo otveta na respiratorno-sintsitial'nuiu virusnuiu infektsiiu u vzroslykh patsientov s razlichnymi formami bronkhita.