[A patient with chronic mucormycosis].
Rhinocerebral mucormycosis was diagnosed in a 75-year-old woman with a history of type II diabetes mellitus. This rare opportunistic infection is caused by fungi belonging to the order of Mucorales. The patient had a severe osteomyelitis of the base of the skull, resulting in complaints of headache and diplopia. She was treated with intravenous colloidal amphotericin B, surgical excision, and later with liposomal amphotericin B. She died of respiratory failure. Mucormycosis is usually a rapidly fulminant infection. This patient showed a remarkably chronic course.
Barge
R M
RM
Academisch Ziekenhuis, Afd. Infectieziekten, Leiden.
Buiting
A G
AG
Thompson
J
J
van't Wout
J W
JW
D000368:Aged; D000666:Amphotericin B / Q000008:administration & dosage / Q000627:therapeutic use; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000382:microbiology*; D002908:Chronic Disease; D005004:Ethmoid Bone; D005260:Female; D006801:Humans; D009091:Mucormycosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D010019:Osteomyelitis / Q000382:microbiology*; D012233:Rhizopus / Q000302:isolation & purification*; D014057:Tomography, X-Ray Computed
D000666:Amphotericin B
Een patiënt met chronische mucormycosis.