title: [The effect of chenotherapy on the reservoir function of the gallbladder in cholelithiasis patients].
abstract: The effect of chenodeoxycholic acid (CDCA) on the reservoir function of the gallbladder was studied in 46 patients with cholesterol cholelithiasis. There was a dependence between a clear increase of filling of the gallbladder in patients treated by this method with subsequent sharp reduction of its size and development of dyspepsia and diarrhea. In 14 patients increase of the gallbladder against the background of chemotherapy was not authentic but no dyspeptic phenomena occurred. Thus, decompensation of the reservoir function of the gallbladder in patients with cholelithiasis against the background of chemotherapy are manifested by a significant increase of the gallbladder size with subsequent emptying of bile into the duodenum and development of collagenous diarrhea.
authors.forename: T D
authors.initials: TD
authors.lastname: Nykula
authors.forename: I V
authors.initials: IV
authors.lastname: Pavlyk
authors.forename: O B
authors.initials: OB
authors.lastname: Dynnyk
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002635:Chenodeoxycholic Acid / Q000627:therapeutic use*; D002769:Cholelithiasis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D005704:Gallbladder / Q000000981:diagnostic imaging; D016473:Gallbladder Emptying / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014463:Ultrasonography
chemical_list: D002635:Chenodeoxycholic Acid
vernacular_title: Vplyv khenoterapiï na rezervuarnu funktsiiu zhovchnoho mikhura u khvorykh na kholelitiaz.