The clearance rate of plasma kallikrein by the liver increases during the acute-phase response to inflammation.
The effect of the acute-phase response on the clearance rate of plasma kallikrein by the exsanguinated liver was studied in three groups of rats: a control group and two other groups that received either turpentine or an endogenous pyrogen preparation. The plasma kallikrein clearance rates were significantly higher in both inflamed groups.
Martins
B
B
Department of Medicine (Gastroenterology Division), Escola Paulista de Medicina, Sao Paulo, Brasil.
Kouyoumdjian
M
M
Limaos
E A
EA
Borges
D R
DR
D000210:Acute-Phase Reaction / Q000139:chemically induced / Q000378:metabolism*; D000818:Animals; D007610:Kallikreins / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D051379:Mice; D011749:Pyrogens; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar; D014425:Turpentine
D011749:Pyrogens; D007610:Kallikreins; D014425:Turpentine