Hormonal responses to exercise during moderate cold exposure in young vs. middle-age subjects.
The influence of moderate cold exposure on the hormonal responses of atrial natriuretic factor (ANF), arginine vasopressin (AVP), catecholamines, and plasma renin activity (PRA) after exhaustive exercise was studied in 9 young and 10 middle-aged subjects. Exercise tests were randomly performed in temperate (30 degrees C) and cold (10 degrees C) environments. Heart rate, oxygen consumption, and peripheral arterial blood pressure were measured at regular intervals. Blood samples were collected before and immediately after exercise at 30 or 10 degrees C. Plasma sodium and potassium concentrations as well as hemoglobin and hematocrit were measured, and the change in plasma volume was calculated. At rest and during exercise, oxygen consumption was similar during exposure to both temperate and cold temperatures. During submaximal exercise intensities, the rise in heart rate was blunted while the increase in systolic blood pressure was significantly greater at 10 than at 30 degrees C. The increases in plasma sodium and potassium concentrations after exhaustion were similar between environments, as was the decrease in plasma volume. In both groups, all plasma hormones were significantly elevated postexercise, with the AVP response similar at 10 and 30 degrees C. However, the norepinephrine and ANF responses were significantly greater while the PRA response was significantly reduced at 10 degrees C. In the middle-aged subjects the epinephrine response to exercise was higher at 10 than at 30 degrees C. The greater ANF and reduced PRA responses to exercise in the cold may have resulted from central hemodynamic changes caused by cold-induced cutaneous vasoconstriction.(ABSTRACT TRUNCATED AT 250 WORDS)
Therminarias
A
A
Centre Hospitalier régional de Grenoble, Faculté de Médecine de Grenoble, La Tronche, France.
Flore
P
P
Oddou-Chirpaz
M F
MF
Gharib
C
C
Gauquelin
G
G
D000328:Adult; D000375:Aging / Q000502:physiology*; D001127:Arginine Vasopressin / Q000097:blood; D009320:Atrial Natriuretic Factor / Q000097:blood; D001642:Bicycling; D002395:Catecholamines / Q000097:blood; D003080:Cold Temperature; D015444:Exercise / Q000502:physiology*; D006400:Hematocrit; D006454:Hemoglobins / Q000378:metabolism; D006728:Hormones / Q000097:blood*; D006801:Humans; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption / Q000502:physiology; D010953:Plasma Volume / Q000502:physiology; D011188:Potassium / Q000097:blood; D012083:Renin / Q000097:blood; D012964:Sodium / Q000097:blood
D002395:Catecholamines; D006454:Hemoglobins; D006728:Hormones; D007773:Lactates; D001127:Arginine Vasopressin; D019344:Lactic Acid; D009320:Atrial Natriuretic Factor; D012964:Sodium; D012083:Renin; D011188:Potassium