title: [Molecular aspects of IL-7-IL-7 receptor system].
abstract: IL-7 is a multifunctional cytokine which acts on cells such as B cells, T cells and macrophages. As the IL-7 clearly plays many important roles the in control of growth and differentiation, it is important to understand how IL-7 and IL-7 receptor (IL-7R) are expressed. Recently, to understand the transcriptional regulation of IL-7 and IL-7R genes, a detailed analysis of the 5' flanking region of the IL-7 and IL-7R genes has been done. In this review recent progress on these topics is introduced and discussed.
authors.forename: T
authors.initials: T
authors.lastname: Sudo
mesh_terms: D000818:Animals; D001483:Base Sequence; D004742:Enhancer Elements, Genetic; D005786:Gene Expression Regulation; D006801:Humans; D015851:Interleukin-7 / Q000235:genetics*; D008969:Molecular Sequence Data; D011971:Receptors, Immunologic / Q000235:genetics*; D020395:Receptors, Interleukin-7; D014158:Transcription, Genetic
chemical_list: D015851:Interleukin-7; D011971:Receptors, Immunologic; D020395:Receptors, Interleukin-7