Intracerebral haemorrhage after thrombolytic therapy for acute myocardial infarction.
Seven cases of intracerebral haemorrhage were identified following the use of thrombolytic therapy in a total of 710 patients with acute myocardial infarction. Each case was reviewed in detail with particular attention to the presenting symptoms. A confusional state was the commonest initial feature. Increased age and male sex were associated with increased risk of cerebral bleed. The possible role of intravenous heparin in increasing risk and the management of affected cases is discussed. Early recognition and action is emphasized.
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Department of Cardiology, Royal Sussex County Hospital, Brighton, UK.
Vincent
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D000367:Age Factors; D000368:Aged; D002543:Cerebral Hemorrhage / Q000139:chemically induced* / Q000150:complications; D003221:Confusion / Q000209:etiology; D006493:Heparin / Q000009:adverse effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D012307:Risk Factors; D012737:Sex Factors; D015912:Thrombolytic Therapy / Q000009:adverse effects*
D006493:Heparin