[Intraperitoneal administration of cisplatin (CDDP) for advanced or recurrent gastric cancer with peritoneal dissemination].
This study was undertaken in order to evaluate the effect of intraperitoneal administration of CDDP on fourteen patients with peritoneal dissemination of advanced or recurrent gastric cancer. The procedure was used together specific hydration transfusion and diuretics. Two patients showed a complete response and 5 patients a partial response. Following this therapy, 2 patients have survived for more than 6 months. Alimentary symptoms (nausea, vomiting) were found but renal toxicity and serious myelosuppression were not recognized in all patients.
Miyamoto
Y
Y
2nd Department of Surgery, Gunma University School of Medicine, Maebashi, Japan.
Morishita
Y
Y
Ohwada
S
S
Nakamura
S
S
Takeyoshi
I
I
Tanahashi
Y
Y
Kusaba
T
T
Usui
R
R
Minaguchi
S
S
Shiozaki
H
H
D000328:Adult; D000368:Aged; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D008297:Male; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000556:secondary; D010538:Peritonitis / Q000188:drug therapy; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology
D002945:Cisplatin