Evaluation of serum total IgE in Chinese allergic children using different assays.
Since differences in HLA groups have been found in Chinese populations, as well as differences in the values of total IgE in China, Japan and Thailand, a study has been done in 44 Chinese children, all of them with a history of atopic conditions divided into five groups: asthma, rhinitis, conjunctivitis, allergic bronchitis and atopic dermatitis. 34 of them were positive against D. pteronyssimus, 8 against cats, 3 against dogs and 3 against fish. The only adult patient studied was positive against gramineal plants (all positivities were tested with the prick test). IVT ELISA Screen is performed against 10 allergens, as well as 3 M FAST-Test and 3 M Total IgE FAST Plus Test. The results show that the majority of children had an elevation of the total IgE in the three tests. There is quite a good agreement between FAST and IgE-IVT and a better correlation between IgE-IVT and IgE FAST Plus. The correlation between IgE FAST and IgE FAST Plus was excellent.
Chang
C C
CC
Department of Internal Medicine, University of California Davis, School of Medicine 95616.
Halpern
G M
GM
Tam
A Y
AY
Lau
Y L
YL
Yeung
C Y
CY
D000328:Adult; D000485:Allergens / Q000276:immunology; D044466:Asian People; D002648:Child; D002681:China; D004198:Disease Susceptibility; D004797:Enzyme-Linked Immunosorbent Assay; D006680:HLA Antigens; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000097:blood / Q000145:classification / Q000208:ethnology* / Q000276:immunology; D007118:Immunoassay / Q000379:methods; D007073:Immunoglobulin E / Q000097:blood*; D007428:Intradermal Tests; D011237:Predictive Value of Tests; D011933:Reagent Kits, Diagnostic
D000485:Allergens; D006680:HLA Antigens; D011933:Reagent Kits, Diagnostic; D007073:Immunoglobulin E