Dysgonic fermenter-3: a bacterium associated with diarrhea in immunocompromised hosts.
We describe two patients with chronic diarrhea associated with dysgonic fermenter-3 (DF-3) infection. One patient had common variable hypogammaglobulinemia and the other hand chronic idiopathic neutropenia and human immunodeficiency virus infection. Specific stool culture techniques were necessary to isolate DF-3. The organism was sensitive to clindamycin, tetracycline, and trimethoprim-sulfamethoxazole. Antibiotic therapy eradicated the organism and the diarrhea resolved in both patients. DF-3 is a little-recognized organism associated with diarrhea in the immunocompromised patient. It should be suspected when routine evaluation and stool cultures are not diagnostic.
Heiner
A M
AM
Division of Gastroenterology, University of Utah School of Medicine, Salt Lake City.
DiSario
J A
JA
Carroll
K
K
Cohen
S
S
Evans
T G
TG
Shigeoka
A O
AO
D000328:Adult; D000361:Agammaglobulinemia / Q000150:complications* / Q000276:immunology; D003967:Diarrhea / Q000382:microbiology*; D005260:Female; D016964:Gram-Negative Anaerobic Cocci; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology*; D015658:HIV Infections / Q000150:complications* / Q000276:immunology; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged