High-dose flunitrazepam anesthesia.
Benzodiazepines have receptors in the nervous system as well as in the kidney, liver, skeletal and ileal muscle, lungs and the heart. Flunitrazepam is a benzodiazepine with pronounced hypnotic effects in the usual dosage. High dose flunitrazepam anesthesia is suggested for prolonged surgical procedures as an alternative to the well known high-dose opiate anesthesia. Its reversal using flumazenil can shorten the post-operative anesthetic effect.
Eldor
J
J
Department of Anesthesia, Misgav Ladach General Hospital, Jerusalem, Israel.
D000758:Anesthesia / Q000379:methods*; D001665:Binding Sites; D001808:Blood Vessels / Q000187:drug effects; D005445:Flunitrazepam / Q000008:administration & dosage* / Q000493:pharmacokinetics / Q000494:pharmacology; D006801:Humans
D005445:Flunitrazepam