Orthostatic tremor associated with voice tremor.
We report a 67-year-old female with orthostatic and voice tremor. Her orthostatic tremor mainly affected her lower extremities, alternating between antagonist muscle groups at a frequency of 4.4-4.8 Hz. The voice tremor ranged between 4.8 and 8.8 Hz. In this case, the frequency of voice tremor was same as that of orthostatic tremor, suggesting a common origin from a tremor-generating mechanism. These tremors were diagnosed as 'forme fruste' of the essential tremor, not the incipient stage of Parkinson's disease. Medications including clonazepam, perphenazine, Dopa and trihexyphenidyl hydrochloride had no effect on both the orthostatic and voice tremors, but propranolol was somewhat beneficial on voice tremor.
Yokota
J
J
Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
Imai
H
H
Seki
K
K
Ninomiya
C
C
Mizuno
Y
Y
D000368:Aged; D004576:Electromyography / Q000187:drug effects; D005260:Female; D006801:Humans; D009132:Muscles / Q000187:drug effects / Q000503:physiopathology; D009460:Neurologic Examination / Q000187:drug effects; D011187:Posture / Q000502:physiology*; D011433:Propranolol / Q000627:therapeutic use; D014202:Tremor / Q000188:drug therapy / Q000503:physiopathology*; D014832:Voice Disorders / Q000188:drug therapy / Q000503:physiopathology*
D011433:Propranolol