[Immunoglobulins in the treatment of herpes zoster].
We have treated 20 patients with Herpes Zoster with "hyperimmune anti-Zoster immunoglobulins" (Uman-VZIG) by intralesional administration, 20 patients with Uman-VZIG by intramuscular administration and 23 patients with acyclovir by intravenous administration. The results of treatment in both groups of patients treated with Uman-VZIG were clinically satisfactory with disappearance of fever, local pain and amelioration of cutaneous lesions after two days from the start of treatment and with a mean duration of disease of five days. In patients treated with acyclovir, signs and symptomatology of disease ameliorated slowly and we have observed a longer mean duration of disease (about 8 days). We concluded that Uman-VZIG, both by intralesional and intramuscular administration, is effective and safe in Herpes Zoster treatment.
Agostini
G
G
Instituto di Clinica Dermatologica, Università degli Studi di Pisa.
Agostini
S
S
D000212:Acyclovir / Q000627:therapeutic use; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006562:Herpes Zoster / Q000188:drug therapy / Q000628:therapy*; D006801:Humans; D007116:Immunization, Passive / Q000379:methods; D015552:Injections, Intralesional; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
D000212:Acyclovir
Le immunoglobuline nel trattamento dell'herpes zoster.