[Vertical transmission of HTLV-I].
Vertical transmission of the human T-cell leukemia type 1 (HTLV-1) from seropositive mothers to their offspring has been extensively studied. Transmission occurs mainly through breastfeeding. Prevention relies on screening pregnant women (and wet-nurses) for HTLV-1 antibodies and advising seropositive women to refrain breast feeding. Recently, antigen detection or genome detection (using PCR) studies on lymphocytes from neonates born to HTLV-1 positive mothers have established that prenatal vertical transmission does occur, although in only a small proportion of cases (0.5 to 7%). Studies on the HTLV-1 and improved understanding of its modes of transmission may provide new insight into the transmission of the HIV.
Denis
F
F
Département de Bactériologie-Virologie, CHU Dupuytren, Limoges, France.
Verdier
M
M
Bonis
J
J
D017218:Cordocentesis; D005260:Female; D015490:HTLV-I Infections / Q000276:immunology / Q000517:prevention & control / Q000635:transmission*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008431:Maternal-Fetal Exchange / Q000276:immunology*; D008895:Milk, Human / Q000382:microbiology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology* / Q000517:prevention & control
Transmission verticale de l'HTLV-1.