title: A probable involvement of rice allergy in severe type of atopic dermatitis in Japan.
abstract: 1006 patients with typical and atypical lesions of atopic dermatitis (AD) were analysed statistically. The clinical severity was closely correlated to serum IgE values and RAST (radio-allergosorbent test) positivity. The frequency of RAST-positive antigens was significantly correlated with serum IgE values (gamma = 0.712; p < 0.01). The analysis of multiple correlation between the clinical severity and each RAST score for mite, egg white and rice antigens suggested a strong contribution of rice allergy to the development of severe AD. 25 patients with severe AD and positive rice-RAST were treated by rice exclusion diet. The results were as follows: 9 cases remarkably responsive, 10 cases moderately responsive and 6 cases unresponsive. The rice-RAST titre decreased most remarkably in the 1st group. The wheat-RAST titre also decreased in the 1st, in spite of taking wheat foods every day, but increased in the 3rd. A probable role of rice allergy in severe AD in Japan is discussed.
authors: Department of Dermatology, Yokohama City University School of Medicine, Japan.
authors: Z
authors: Z
authors: Ikezawa
authors: K
authors: K
authors: Miyakawa
authors: H
authors: H
authors: Komatsu
authors: C
authors: C
authors: Suga
authors: J
authors: J
authors: Miyakawa
authors: A
authors: A
authors: Sugiyama
authors: T
authors: T
authors: Sasaki
authors: H
authors: H
authors: Nakajima
authors: Y
authors: Y
authors: Hirai
authors: Y
authors: Y
authors: Suzuki
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003876:Dermatitis, Atopic / Q000209:etiology* / Q000276:immunology; D005512:Food Hypersensitivity / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007223:Infant; D007564:Japan; D012275:Oryza / Q000009:adverse effects* / Q000276:immunology
chemical_list: D007073:Immunoglobulin E