title: Hepatitis B virus infection in hospital personnel.
abstract: BACKGROUND
  Healthcare workers are known to be prone to infection with the hepatitis B virus. We did this study, as there are only a few reports from India on the prevalence of this infection among hospital personnel, so that a rational and effective immunization policy could be evolved.
  
  
  METHODS
  Eight hundred and sixty-three hospital employees including doctors, nurses, technicians, office workers, orderlies and other ancillary staff were screened by ELISA for both hepatitis B surface antigen and its antibody as indicators of prior infection.
  
  
  RESULTS
  Eighty-six (10%) were found to be seropositive for hepatitis B surface antigen alone while in 138 (16%) only the antibody was detected. We did not come across any subject in whom both the antigen and the antibody were present simultaneously. Seropositivity was associated with a history of contact with blood or blood products, accidental parenteral exposure and direct patient contact. A history of close contact with a known patient with hepatitis and a past history of jaundice showed a weaker association, while a history of surgery or dental treatment was not significantly associated with seropositivity. There was a significantly (p < 0.5) higher seropositivity in males than in females. The seropositivity was also related to the employee's socio-economic status. Working in a dialysis unit carried the greatest risk.
  
  
  CONCLUSIONS
  Energetic steps should be taken in all hospitals for the prevention of hepatitis B virus infection among healthcare workers.
authors: Sir Hurkisondas Nurrotumdas Hospital, Bombay, Maharashtra, India.
authors: A J
authors: AJ
authors: Elavia
authors: D D
authors: DD
authors: Banker
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology*; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000453:epidemiology*; D010564:Personnel, Hospital; D015995:Prevalence; D016036:Seroepidemiologic Studies