Cold wind stimulation reflex.
The bradycardia induced by cold wind blown on the face and the early cephalic release of insulin induced by feeding have been shown to be caused by a vagal reflex stimulation. An experiment was designed to determine whether cold wind blown on the face would induce both pancreatic and cardiac stimulation. A 4 degrees C wind blown on the face for 4 min produced a rapid and persistent bradycardia, which interestingly persisted for up to 35 min after the test. The effect on respiration rate is more gradual and vanishes immediately after cold wind stimulation. Cold wind produced a slight reduction of insulin secretion, as evidenced by the fall of both plasma insulin and C-peptide, and caused a significant increase in plasma norepinephrine. These results suggest that the cold wind action of the vagus nerve is exerted on the heart and that of the sympathetic on the pancreas, whereas during the cephalic phase of feeding a vagal influence is observed on the pancreas and a sympathetic action on the heart. The mechanisms of the quantitative and qualitative control of these autonomic responses are not known and deserve further investigation.
LeBlanc
J
J
Department of Physiology, Faculty of Medicine, Laval University, Quebec City, Canada.
Mercier
I
I
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D001919:Bradycardia / Q000503:physiopathology*; D002096:C-Peptide / Q000097:blood; D003080:Cold Temperature; D004435:Eating / Q000502:physiology; D005934:Glucagon / Q000097:blood; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D007328:Insulin / Q000378:metabolism; D000078790:Insulin Secretion; D008297:Male; D009638:Norepinephrine / Q000097:blood; D010179:Pancreas / Q000378:metabolism; D012018:Reflex / Q000502:physiology*; D015656:Respiratory Mechanics / Q000502:physiology; D014276:Trigeminal Nerve / Q000502:physiology; D014630:Vagus Nerve / Q000502:physiology; D014919:Wind
D001786:Blood Glucose; D002096:C-Peptide; D007328:Insulin; D005934:Glucagon; D009638:Norepinephrine