Lack of enterohepatic circulation of the active metabolite of nabumetone in humans.
Brett
M A
MA
Clinical Pharmacology Research Institute, SmithKline Beecham Pharma, Neuss, Germany.
Buscher
G
G
Ellrich
E
E
Greb
W H
WH
Kurth
H J
HJ
Rülander
G
G
Schmerenbeck
B
B
Haddock
R
R
Thawley
A
A
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000378:metabolism; D002074:Butanones / Q000378:metabolism*; D002792:Cholestyramine Resin / Q000494:pharmacology; D004311:Double-Blind Method; D004764:Enterohepatic Circulation; D006801:Humans; D008297:Male; D000077430:Nabumetone; D009280:Naphthaleneacetic Acids / Q000097:blood*; D009994:Osmolar Concentration; D010919:Placebos; D013997:Time Factors
D000894:Anti-Inflammatory Agents, Non-Steroidal; D002074:Butanones; D009280:Naphthaleneacetic Acids; D010919:Placebos; D002792:Cholestyramine Resin; C044612:6-methoxy-2-naphthylacetic acid; D000077430:Nabumetone