title: [The preventive activity of monoclonal antibodies specific to the lipopolysaccharide of Francisella tularensis].
abstract: The preventive activity of five monoclonal antibodies (McAb) in experimental tularemia was evaluated. McAb produced by hybridoma FB11-k (IgG2a), specific to F. tularensis lipopolysaccharide, prevented the death of mice and guinea pigs infected with F. tularensis virulent strain 503 of the holarctic subspecies.
authors: V S
authors: VS
authors: Khlebnikov
authors: S S
authors: SS
authors: Vetchinin
authors: G K
authors: GK
authors: Grechko
authors: A A
authors: AA
authors: Averina
authors: I R
authors: IR
authors: Golovlev
authors: S F
authors: SF
authors: Averin
authors: V E
authors: VE
authors: Zhemchugov
authors: S I
authors: SI
authors: Konovalov
authors: G A
authors: GA
authors: Anisimov
authors: S S
authors: SS
authors: Afanas'ev
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology* / Q000302:isolation & purification; D000918:Antibody Specificity / Q000276:immunology*; D004353:Drug Evaluation, Preclinical; D005604:Francisella tularensis / Q000276:immunology* / Q000472:pathogenicity; D006168:Guinea Pigs; D006825:Hybridomas / Q000276:immunology; D008070:Lipopolysaccharides / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D013997:Time Factors; D014406:Tularemia / Q000276:immunology / Q000517:prevention & control*; D014774:Virulence / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal; D008070:Lipopolysaccharides
vernacular_title: Preventivnaia aktivnost' monoklonal'nykh antitel, spetsifichnykh k lipopolisakharidu Francisella tularensis.