[Regression of coronary arteriosclerosis with hypolipidemic treatment, myth or reality?].
Coronary atherosclerosis regression with hypolipemiant treatment is a well known fact in the animal model since years ago. In humans, during these last years, several clinical trials have been performed to ellucidate the truth to this fact. All of these clinical trials have in common the evolutive study of the coronary lesions with angiographies, in patients following treatment with diet, surgery or drugs, to reduce plasmatic cholesterol. Clinical, analytical and angiographic results of said studies are reviewed. We conclude that the bigger the lowering in plasmatic cholesterol levels, smaller is the progression of these coronary lesions and more probable is finding patients with partial regression of the lesions.
Lahoz
C
C
Unidad de Arterioesclerosis, Instituto de Salud Carlos III, Fundación Jiménez Díaz, Madrid.
Monereo
A
A
Mostaza
J M
JM
de Oya
M
M
D002986:Clinical Trials as Topic; D003324:Coronary Artery Disease / Q000188:drug therapy*; D006801:Humans; D012074:Remission Induction
Regresión de la arterioesclerosis coronaria con tratamiento hipolipidemiante, mito o realidad?