Evaluation of the Pharmacia CAP System, a new test for allergic diagnosis (cedar pollinosis).
For the diagnosis of allergic rhinitis we measured the specific IgE and the total serum IgE in the blood. Although we had measured them by the conventional Phadebas RAST and the Pharmacia IgE RIA before, we now adopted the new Pharmacia CAP System (CAP RAST FEIA and CAP IgE FEIA). To compare these methods, we measured the specific IgE to the cedar pollen and total serum IgE in the same blood of 224 hospital staff at the regular physical examination. As a result the new Pharmacia CAP System proved to be simpler, safer, faster, easier, more specific, and more sensitive than the Phadebas RAST and the Pharmacia IgE RIA. And also these methods correlated well with each other.
Nishikawa
K
K
Department of Otolaryngology, Shuto General Hospital, Yamaguchi, Japan.
Nishikawa
M
M
Teramoto
N
N
Hamamoto
N
N
Ishiguro
K
K
D000328:Adult; D000485:Allergens / Q000276:immunology*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007073:Immunoglobulin E / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011058:Pollen / Q000276:immunology*; D011852:Radioallergosorbent Test; D006255:Rhinitis, Allergic, Seasonal / Q000175:diagnosis* / Q000209:etiology / Q000276:immunology; D012680:Sensitivity and Specificity
D000485:Allergens; D007073:Immunoglobulin E