Glomerular/tubular mixed-type proteinuria in a 3-year-old boy with mental retardation and hyperkinesis.
A 3-year-old boy with mixed glomerular/tubular proteinuria, mental retardation, and hyperkinesis is described. The proteinuria was discovered at the age of 3 years on urinary mass screening. Most of the urinary protein consisted of albumin, accompanied by increases in low molecular weight proteins, including beta 2-microglobulin and alpha 1-microglobulin. Mixed glomerular/tubular proteinuria is known to be caused by the following conditions: chronic renal failure, chronic pyelonephritis, cadmium poisoning, tubulointerstitial nephritis of various etiologies, and after strenuous, short-term, exhaustive exercise. The present patient did not display any of these disorders or conditions.
Kawakami
H
H
Department of Pediatrics, Yamaguchi University School of Medicine, Japan.
Murakami
T
T
D002675:Child, Preschool; D006801:Humans; D006948:Hyperkinesis / Q000150:complications*; D008607:Intellectual Disability; D007678:Kidney Glomerulus; D007684:Kidney Tubules; D008297:Male; D008970:Molecular Weight; D011507:Proteinuria / Q000150:complications* / Q000652:urine