title: A review of biointeractions of Ni and Mg. I. Enzyme, endocrine, transport, and skeletal systems.
abstract: Magnesium (Mg) and nickel (Ni) are biologically active elements in higher animals. Recent studies in vivo as well as in vitro point to interactions of Ni and Mg; non-immunological roles of these elements are reviewed here. Ni and Mg play roles in some of the same enzyme and endocrine systems, body and cell structures, and transport systems. Mg status has determined some responses to dietary Ni. Information available at this time is inadequate to permit assessment of all functions of Mg and Ni and their interactions in human populations. Evidence to date, however, warrants further investigation of the nutritional and metabolic relationships between these elements, over wide ranges of dietary intakes or exposure levels.
authors: Agricultural Experiment Station, University of Arkansas, Fayetteville.
authors: M A
authors: MA
authors: Kenney
authors: H
authors: H
authors: McCoy
mesh_terms: D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D004702:Endocrine Glands / Q000378:metabolism; D004798:Enzymes / Q000378:metabolism; D006801:Humans; D008274:Magnesium / Q000378:metabolism* / Q000502:physiology; D009132:Muscles / Q000378:metabolism; D009532:Nickel / Q000378:metabolism*; D009747:Nutritional Physiological Phenomena
chemical_list: D004798:Enzymes; D009532:Nickel; D008274:Magnesium