title: [Renal crisis in scleroderma].
abstract: A case is described of a 30-year-old woman with scleroderma renal crisis. She presented with classical symptoms: malignant hypertension of sudden onset and rapidly progressive renal failure. End-stage renal failure developed in spite of treatment with angiotensin converting enzyme inhibitors and the patient became dialysis-dependent. Five years later her condition was still stable. She lived in a nursing home, severely disabled but mentally healthy. A renal crisis is one of the most life threatening complications of scleroderma. By immediate treatment with ACE inhibitors, dependence on haemodialysis can be prevented in half the patients.
authors: Academisch Ziekenhuis, afd. Nierziekten, Leiden.
authors: W J
authors: WJ
authors: Fagel
authors: L A
authors: LA
authors: van Es
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology* / Q000628:therapy; D000328:Adult; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006974:Hypertension, Malignant / Q000209:etiology*; D010530:Peritoneal Dialysis; D012595:Scleroderma, Systemic / Q000150:complications*
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors
vernacular_title: Renale crisis bij sclerodermie.