Did the ancestral globin gene of plants and animals contain only two introns?
All vertebrate globin genes contain two introns, while plant globin genes contain three. It is widely thought that the plant gene structure reflects the structure of the primordial globin gene and that a common ancestor of all animals lost the central intron shortly after the divergence of plants and animals more than one billion years ago. The recent discovery of a discordant central intron in some animal globin genes suggests that this model is incorrect. We propose that the typical vertebrate two-intron gene structure is the primordial eukaryotic form, and that following the divergence of plants and animals, a common ancestor of plants gained a central intron in the globin gene.
Dixon
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B
Department of Biology, Dalhousie University, Halifax, Nova Scotia, Canada.
Pohajdak
B
B
D000595:Amino Acid Sequence; D000818:Animals; D005075:Biological Evolution; D005914:Globins / Q000235:genetics*; D007438:Introns / Q000235:genetics*; D008969:Molecular Sequence Data; D009348:Nematoda / Q000235:genetics*; D010944:Plants / Q000235:genetics*
D005914:Globins