[The morphological aspects of the protective action of enterosorbent K(2)9 during the use of the antitumor anthracycline antibiotic carminomycin].
The authors substantiate morphologically the protector effect of K(2)9 enterosorbent during its parallel use with the antitumour anthracyclin antibiotic carminomycin. The agent was administered intraperitoneally in animals at the maximum tolerable dose. Use of the K(2)9 enterosorbent reduces the cardiotoxic effect of carminomycin.
Ishchenko
V E
VE
Blagodarov
V N
VN
Kulik
G I
GI
Grigor'eva
N N
NN
D000818:Animals; D002360:Carubicin / Q000627:therapeutic use* / Q000633:toxicity; D004353:Drug Evaluation, Preclinical; D016061:Enterosorption; D006321:Heart / Q000187:drug effects / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects; D006651:Histocytochemistry; D051379:Mice; D008810:Mice, Inbred C57BL; D008854:Microscopy, Electron; D009206:Myocardium / Q000378:metabolism / Q000473:pathology*; D013997:Time Factors
D002360:Carubicin
Morfologicheskie aspekty protektornogo deĭstviia énterosorbenta K(2)9 pri primenenii protivoopukholevogo antratsiklinovogo antibiotika karminomitsina.