Efficiency of grain production and latent image fading in F-18 micro-autoradiography.
In 18F micro-autoradiography using a frozen section method, the grain production was measured relative to the exposure time and radioactivity. The grain production increased until 6-hr exposure, but 7-hr or longer exposure induced a characteristic of latent image fading. However, the ratios of the efficiency of grain production between two different 18F-radioactivities (11.9 and 2.3 mBq/100 microns2) were constant over experimental exposure times, thus indicating that quantitative analysis by grain counting is preserved.
Yamada
S
S
Department of Radiology and Nuclear Medicine, Tohoku University, Sendai.
Kubota
R
R
Kubota
K
K
Ishiwata
K
K
Ido
T
T
D000818:Animals; D001345:Autoradiography / Q000379:methods*; D005462:Fluorine Radioisotopes; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL
D005462:Fluorine Radioisotopes