title: Kimura's disease and angiolymphoid hyperplasia with eosinophilia: clinical and histopathologic differences.
abstract: BACKGROUND
  There has been considerable controversy about the relation between Kimura's disease and angiolymphoid hyperplasia with eosinophilia (ALHE).
  
  
  OBJECTIVE
  We describe the clinical and histopathologic differences between the two diseases.
  
  
  METHODS
  We reviewed clinical findings and histopathologic changes in two cases of Kimura's disease and three cases of ALHE.
  
  
  RESULTS
  Kimura's disease shows typical lymphoid follicles. It is associated with lymphadenopathy and is always accompanied by peripheral eosinophilia. ALHE shows typical changes in endothelial cells. It is characterized by superficial papules or nodules with no lymphadenopathy and is less frequently accompanied by peripheral eosinophilia.
  
  
  CONCLUSIONS
  Kimura's disease and ALHE are separate entities.
authors: Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea.
authors: S I
authors: SI
authors: Chun
authors: H G
authors: HG
authors: Ji
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000145:classification / Q000188:drug therapy / Q000473:pathology*; D003452:Cryosurgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D000305:Adrenal Cortex Hormones