[Chromosome aberrations in chronic myeloid leukemia].
Chromosome Philadelphia is a cytogenetic marker of chronic myeloid leukemia. It results from a translocation t(9;22) or other, more complex, translocations. Before the onset of blastic crisis, secondary aberrations occur, the most often--trisomy 8, isochromosome 17q and extra Ph chromosome. Their presence has a prognostic significance. Particular aberrations may occur in association with determined haematological and clinical features.
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Katedry i Zakładu Patofizjologii AM, Wrocławiu.
D001752:Blast Crisis / Q000209:etiology / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007621:Karyotyping; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000209:etiology / Q000235:genetics* / Q000473:pathology; D010677:Philadelphia Chromosome; D014178:Translocation, Genetic / Q000235:genetics*; D014314:Trisomy
Aberracje chromosomów w przewlekłej białaczce szpikowej.