[Dual nuclides SPECT for ventilation and perfusion study].
Dual nuclides SPECT using 81mKr and 99mTc-MAA for ventilation and perfusion study was performed in 24 subjects. Crosstalk of 81mKr to 99mTc-energy window was about 7.5% when ventilation and perfusion study were performed by 370 MBq of 81mKr gas and 185 MBq of 99mTc-MAA. Areas of low V/Q was significantly larger in SPECT study than in planar study, in 11 cases with various pulmonary diseases. High V/Q mismatches were also more clearly delineated in SPECT than in planar study. Dual nuclides SPECT study has advantages of obtaining V/Q distribution without movement artifacts and of simultaneous acquisition of ventilation and perfusion image. Area of high V/Q became larger in SPECT with crosstalk than in SPECT without crosstalk, but in the low V/Q area no significant difference was noted between SPECT with crosstalk and without crosstalk.
Goto
E
E
Department of Radiology, Jikei University School of Medicine.
Kawakami
K
K
Takahashi
T
T
Moriya
E
E
Sekine
H
H
Ohwaki
K
K
Nakagawa
M
M
Shimada
T
T
D005260:Female; D006801:Humans; D007727:Krypton Radioisotopes; D008297:Male; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging* / Q000503:physiopathology; D013668:Technetium Tc 99m Aggregated Albumin; D015899:Tomography, Emission-Computed, Single-Photon; D014692:Ventilation-Perfusion Ratio / Q000502:physiology*
D007727:Krypton Radioisotopes; D013668:Technetium Tc 99m Aggregated Albumin