Growth hormone, IGF-I, and testosterone responses to resistive exercise.
It has been suggested that growth hormone (GH), testosterone (T), and insulin-like growth factor I (IGF-I) play large roles in muscle tissue growth; however, in only two investigations IGF-I responses to resistive exercise have been examined. Eight young males who had not weight trained for a minimum of 5 months participated in the study. Three sets of bench press (BP), lat-pull (LP), leg extension (LE), and leg curl (LC) exercises were performed at a 10-RM load for 10 repetitions or until failure. Blood samples were collected from an IV catheter before exercise (-30 min and -10 min), after each individual exercise (BP, LP, LE, LC), and after the exercise session (+5, +15, +25, +35, +95 min; +5:35, +22:30, and +23:30 h). GH, IGF-I, and T determinations were corrected for plasma volume change. GH significantly increased (P < 0.05), but IGF-I did not change. Correction for plasma volume accounted for significant increases in T, but did not account for GH and IGF-I results. These data suggest that moderate resistive exercise may increase GH concentrations, whereas elevated T levels can be accounted for by exercise-induced alteration of plasma volume.
Kraemer
R R
RR
Department of Health, Physical Education, and Dance, Southeastern Louisiana University, Hammond 70402.
Kilgore
J L
JL
Kraemer
G R
GR
Castracane
V D
VD
D000328:Adult; D015444:Exercise / Q000502:physiology*; D013006:Growth Hormone / Q000097:blood*; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000032:analysis*; D007773:Lactates / Q000097:blood; D008297:Male; D010806:Physical Education and Training; D010953:Plasma Volume; D013739:Testosterone / Q000097:blood*; D013997:Time Factors
D007773:Lactates; D013739:Testosterone; D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone