Effects of resin swelling and substitution on solid phase synthesis.
Resins sold by several companies were examined for swelling, uniformity of beads, and substitution in the case of resins sold with the first amino acid attached. Effects of resin swelling, uniformity, and substitution on the solid phase synthesis of long, structured and/or branched peptides were evaluated.
Pugh
K C
KC
Department of Biochemistry, University of Colorado School of Medicine, Denver.
York
E J
EJ
Stewart
J M
JM
D000595:Amino Acid Sequence; D008863:Microspheres; D008969:Molecular Sequence Data; D010455:Peptides / Q000138:chemical synthesis*; D017433:Protein Structure, Secondary; D012117:Resins, Synthetic / Q000737:chemistry*
D010455:Peptides; D012117:Resins, Synthetic