title: Clotest (rapid urease test) in the diagnosis of Helicobacter pylori infection.
abstract: Over a period of 3 months, 85 patients who underwent gastroscopy had antral biopsy taken for Clotest, histology and/or culture for Helicobacter pylori (HP). The sensitivity and specificity of Clotest were found to be 77% and 96% respectively with negative predictive value of 63% and positive predictive value of 98%. Ninety-two percent of the positive Clotests were positive within 20 minutes, thus giving rapid result. Therefore, Clotest is a rapid, sensitive and highly specific test for HP infection. A high correlation between HP infection and chronic gastritis was noted and the prevalence of HP infection in patients with duodenal ulcer (90%) was higher than that of gastric ulcer (64%) or non-ulcer group (65%).
authors: Department of Medicine, Toa Payoh Hospital Pte Ltd, Singapore.
authors: T M
authors: TM
authors: Ng
authors: K M
authors: KM
authors: Fock
authors: J
authors: J
authors: Ho
authors: A L
authors: AL
authors: Tan
authors: S C
authors: SC
authors: Chia
authors: C K
authors: CK
authors: Yap
authors: C N
authors: CN
authors: Chew
authors: E N
authors: EN
authors: Chee
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005753:Gastric Mucosa / Q000201:enzymology; D005756:Gastritis / Q000175:diagnosis / Q000382:microbiology*; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000201:enzymology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011933:Reagent Kits, Diagnostic; D014510:Urease / Q000032:analysis*
chemical_list: D011933:Reagent Kits, Diagnostic; D014510:Urease