[Analysis of natural history and long-term follow-up of 59 patients with obliterative pulmonary hypertension (OPH)].
The diagnosis of OPH was made by clinical and hemodynamic data in 59 patients, including 30 cases of unexplained pulmonary hypertension, 26 cases of pulmonary embolism and 3 others. The survival curve showed that the two-year survival rate of the patients was 76.72%, and the five-year rate was 63.37%. The single correlation factors influencing prognosis were the interval from onset of symptoms to diagnosis (course), cardiac function, PaO2, SaO2, cause of disease, pulmonary artery pressure and right atrial pressure. The outcome of long-term treatment (mean 4.2 years) in 15 patients with OPH was as follows: remarkable improvement in 8 cases, amelioration in 3, no change in 2 and deterioration in 2. The total effective rate was 73.33%. The importance of anticoagulant therapy and the use of nifedipine are discussed.
Cheng
X
X
Cardiovascular Institute, Beiing.
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000627:therapeutic use; D011379:Prognosis; D011655:Pulmonary Embolism / Q000188:drug therapy / Q000401:mortality*; D015996:Survival Rate
D009543:Nifedipine