[Primary hemostasis studies in Conn syndrome].
The various components of haemostasis seems to be affected by the high cortisol level in Cushing's disease. Increase in coagulation factor levels, decreased fibrinolysis, high von Willebrand factor plasmatic levels along with easy bruising due to vascular damage have been described. In this report a similar but less accentuated elevation of von Willebrand factor levels are documented in aldosterone producing adrenocortical adenoma, and in the same time enhanced platelet activation was also found. The primary haemostatic alterations correlated well with aldosterone levels and subsided significantly after the removal of the ademonas. Further studies seem to be desirable to analyse and elucidate haemostatic functions in Conn's syndrome.
Udvardy
M
M
Debreceni Orvostudományi Egyetem, II. Belgyógyászati Klinika.
Hársfalvi
J
J
Rák
K
K
D000328:Adult; D000450:Aldosterone / Q000097:blood; D001777:Blood Coagulation; D001794:Blood Pressure; D005260:Female; D006487:Hemostasis; D006801:Humans; D006929:Hyperaldosteronism / Q000097:blood*; D008297:Male; D013577:Syndrome; D014841:von Willebrand Factor / Q000032:analysis*
D014841:von Willebrand Factor; D000450:Aldosterone
A primer haemostasis vizsgálata Conn-szindrómában.