[The composition and physicochemical properties of the blood lipoproteins in rats exposed to external gamma irradiation].
Content of lipids, character of chemiluminescence of blood plasma and certain classes of lipoproteins have been studied. Geometrical parameters, nature and quantity of charged groups of lipoprotein particles accessible for titration have been determined 1 and 30 days after a single external gamma irradiation of rats in a dose of 3 Gy. The used irradiation dose exerts an expressed hyperlipidemic effect retained for one month after irradiation. The disturbances in the spectrum of blood lipids and lipoproteins are of hyper-beta and hyper-prebeta lipoproteinemia character. Considerable disturbances of physicochemical properties of different classes of lipoproteins have been detected. They are exhibited in changes of the pattern of free-radical processes, state of the charge of surface ionogenic groups and geometrical parameters of lipoprotein particles. Changes registered by the methods of potentiometric titration and correlation spectroscopy are most expressed in lipoproteins of very low density and those of low density.
Chaialo
P P
PP
Liakhovchuk
N N
NN
Chobot'ko
G M
GM
Voziian
P A
PA
Kholodova
Iu D
IuD
D000818:Animals; D001797:Blood Protein Electrophoresis; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003720:Densitometry; D004589:Electrophoresis, Disc; D005720:Gamma Rays; D006863:Hydrogen-Ion Concentration; D006951:Hyperlipoproteinemias / Q000097:blood / Q000209:etiology; D008074:Lipoproteins / Q000097:blood / Q000737:chemistry / Q000528:radiation effects*; D008163:Luminescent Measurements; D008297:Male; D011833:Radiation Injuries, Experimental / Q000097:blood; D051381:Rats; D011916:Rats, Inbred F344; D013997:Time Factors
D008074:Lipoproteins
Sostav i nekotorye fiziko-khimicheskie svoĭstva lipoproteinov krovi krys pri vozdeĭstvii vneshnego gamma-oblucheniia.