The genes coding for phosphoenolpyruvate carboxykinase-1 (PCK1) and neuronal nicotinic acetylcholine receptor alpha 4 subunit (CHRNA4) map to human chromosome 20, extending the known region of homology with mouse chromosome 2.
The mouse genes for cytosolic phosphoenolpyruvate carboxykinase-1 (Pck-1) and neuronal nicotinic acetylcholine receptor alpha 4 subunit (Acra-4) both map to distal chromosome 2 (Siracusa et al. 1989; Bessis et al. 1990). We have utilized Southern blot analysis on human/rodent somatic cell hybrids to map the human homologues of both of these genes, PCK1 and CHRNA4, to human chromosome 20.
Pilz
A J
AJ
Department of Genetics and Biometry, University College London, England.
Willer
E
E
Povey
S
S
Abbott
C M
CM
D000818:Animals; D015139:Blotting, Southern; D002874:Chromosome Mapping; D002890:Chromosomes, Human, Pair 20; D006224:Cricetinae; D006801:Humans; D006822:Hybrid Cells / Q000648:ultrastructure; D051379:Mice / Q000235:genetics; D010729:Phosphoenolpyruvate Carboxykinase (GTP) / Q000235:genetics*; D051381:Rats; D011978:Receptors, Nicotinic / Q000235:genetics*; D013045:Species Specificity
D011978:Receptors, Nicotinic; D010729:Phosphoenolpyruvate Carboxykinase (GTP)