Effect of "Rosa Canina" infusion and magnesium on the urinary risk factors of calcium oxalate urolithiasis.
The effects on the calcium oxalate urolithiasis urinary risk factors of "Rosa Canina", in herb infusion form, and magnesium chloride have been studied using female Wistar rats under balanced dietary conditions. No significant effects on the volume of liquids drunk or on creatinine, phosphate, and oxalate urinary concentrations and excretions were observed. The herb infusion did not cause any diuretic effect. Calciuria decreased and citraturia increased when taking the herb infusion, and vice versa when taking magnesium chloride. Magnesium chloride decreased the urinary pH value, but this effect was not observed when magnesium chloride was administered with herb infusion. In conclusion, the same beneficial effects of the studied infusion herb on calcium oxalate urolithiasis urinary risk factors can be clearly detected. An interesting fact is that it seems that some possible effects depend on dietary components, thus, i.e., an increase in the urinary pH was only detected when the intake of the herb infusion was studied in a magnesium chloride-supplemented diet.
Grases
F
F
Department of Chemistry, University of Balearic Islands, Palma de Mallorca, Spain.
Masárová
L
L
Costa-Bauzá
A
A
March
J G
JG
Prieto
R
R
Tur
J A
JA
D000818:Animals; D002129:Calcium Oxalate; D005260:Female; D008274:Magnesium / Q000627:therapeutic use; D019684:Magnoliopsida; D051381:Rats; D017208:Rats, Wistar; D012307:Risk Factors; D014545:Urinary Calculi / Q000737:chemistry / Q000517:prevention & control*
D002129:Calcium Oxalate; D008274:Magnesium