Malignant anterior uveal melanoma with diffuse metastasis in a dog.
Enucleation was performed in 10-year-old sexually intact female mixed-breed German Shepherd Dog. Histologic examination revealed that the dog had an uveal amelanotic melanoma of the eye. The tumor consisted of anaplastic cells with a high mitotic index, indicating malignancy. On examination 3 months after enucleation, the dog had difficulty breathing and nasal discharge. Radiography revealed pulmonary metastasis. The dog was euthanatized. Necropsy revealed diffuse metastasis involving various organs.
Minami
T
T
Department of Pathology, Speyer Hospital and Caspary Research Institute, New York, NY 10021.
Patnaik
A K
AK
D000818:Animals; D004283:Dog Diseases / Q000473:pathology* / Q000601:surgery; D004285:Dogs; D015353:Eye Enucleation / Q000662:veterinary*; D005260:Female; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000556:secondary / Q000662:veterinary*; D008545:Melanoma / Q000473:pathology / Q000556:secondary / Q000601:surgery / Q000662:veterinary*; D014604:Uveal Neoplasms / Q000473:pathology / Q000601:surgery / Q000662:veterinary*