[Experimental infection of sheep with a rabies virus of canine origin: study of the pathogenicity for that species].
The effects of the inoculation of a canine strain of rabies virus in sheep were studied using ten animals which received different amounts of this virus. Two subjects, inoculated with 10(5.4) mouse intracerebral lethal doses 50% (MICLD50), died from rabies after 19 and 40 days of incubation. Clinical signs were anorexia, emaciation, nervous reactions and prostration before death. The virus was recovered from different parts of the central nervous system and salivary glands with high titres. Only three animals showed an antibody response, at very low levels.
Soria Baltazar
R
R
Consejo Nacional de Ciencia y Tecnología, Laboratoire d'études sur la rage et la pathologie des animaux sauvages, Malzéville, Francia.
Artois
M
M
Blancou
J
J
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002490:Central Nervous System / Q000382:microbiology; D004283:Dog Diseases / Q000382:microbiology*; D004285:Dogs; D005260:Female; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D011818:Rabies / Q000382:microbiology / Q000662:veterinary*; D011820:Rabies virus / Q000276:immunology / Q000302:isolation & purification / Q000472:pathogenicity*; D012469:Salivary Glands / Q000382:microbiology; D012756:Sheep; D012757:Sheep Diseases / Q000382:microbiology*; D013047:Specific Pathogen-Free Organisms
D000914:Antibodies, Viral
Infección experimental de ovinos por un virus de la rabia de origen canino: estudio del poder patógeno para esta especie.