Survival and causes of death among patients with Yersinia enterocolitica infection. A Norwegian 10-year follow-up study on 458 hospitalized patients.
The aim of the present study was to elucidate the possible influence of the Yersinia enterocolitica infection on long-time survival, and to describe clinical conditions associated with a fatal issue. During the period 1974-83, Y. enterocolitica infection was diagnosed in 458 hospitalized patients by antibody response or isolation of the microorganism. The patients were followed for 4-14 years (until 1987). The observed cumulative survival rates for female patients, and for the whole material, deviated significantly from the expected rates for 10 and 8 years. Two patients died in association with the acute infection, and 2 died from malignant mesothelioma during the first year of observation. 4/42 other patients died during the follow-up period from chronic multiorgan disease, 9 from malignant disease, and 2 died from hematological disorders. A very high mortality (10/22) was observed among patients who had developed chronic liver disease subsequently to the infection. We conclude that chronic conditions associated with the Y. enterocolitica infection may exert a substantial impact on long-time survival.
Saebø
A
A
Institute of Surgery, Bergen University Hospital, Norway.
Lassen
J
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008109:Liver Diseases, Parasitic / Q000209:etiology / Q000401:mortality*; D008297:Male; D008654:Mesothelioma / Q000209:etiology / Q000401:mortality*; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000209:etiology / Q000401:mortality*; D009664:Norway / Q000453:epidemiology; D015996:Survival Rate; D015009:Yersinia Infections / Q000150:complications / Q000401:mortality*; D015008:Yersinia enterocolitica