Statistical testing of equality of two break-points in experimental data.
Two examples in quantitative biology are examined to emphasize the need for two-phase regression models: the osmotic behaviour of cells and the non-linear temperature kinetics of membrane-bound enzyme systems. Existing statistical techniques are inadequate to test the equality of break-points of two data sets for specific reasons. We suggest here a pragmatic solution by way of a computer programme useful in applying two-phase regression models to such data sets wherein a decision needs to be made whether the critical transition differs or not.
Shanubhogue
A
A
Department of Statistics, University of Poona, India.
Rajarshi
M B
MB
Gore
A P
AP
Sitaramam
V
V
D000465:Algorithms; D000818:Animals; D004912:Erythrocytes / Q000502:physiology; D004926:Escherichia coli; D066298:In Vitro Techniques; D007700:Kinetics; D008930:Mitochondria, Liver / Q000502:physiology; D015233:Models, Statistical; D009994:Osmolar Concentration; D051381:Rats; D012965:Sodium Chloride / Q000494:pharmacology; D012984:Software; D013696:Temperature
D012965:Sodium Chloride