Venous engorged tissue flaps treated with medicinal leeches.
We evaluated the ability of leeches to improve the tolerance of pedicle flaps to periods of venous congestion. Axial pedicle flaps were created on 14 rabbit ears; the venous circulation of each flap was compromised with a suture ligature. Medicinal leeches were applied to seven flaps; the other seven flaps were untreated. Tissue viability was assessed by both clinical examination and fluorometric analysis of fluorescein dye delivery. Leech-treated flaps showed poorer reperfusion than untreated flaps. No statistically significant difference was found in comparing the two groups.
Rodgers
I R
IR
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston.
Grove
A S
AS
Silverman
D G
DG
D000818:Animals; D001815:Bloodletting; D002470:Cell Survival; D004423:Ear / Q000098:blood supply; D019793:Fluorescein; D005452:Fluoresceins / Q000378:metabolism; D006085:Graft Survival; D007865:Leeches; D011817:Rabbits; D012039:Regional Blood Flow; D013524:Surgical Flaps / Q000502:physiology*
D005452:Fluoresceins; D019793:Fluorescein