The diagnostic value of mucinous carcinoma-associated antigen (MCA) tests in breast carcinomas.
MCA (Mucinous Carcinoma-Associated Antigen) levels of 176 breast carcinoma patients were tested postoperatively by serial determination. One hundred forty-one patients had non-progressive disease (PD-) while 35 were in the progressive phase (PD+); in the latter the diagnosis was confirmed by means of current diagnostic procedures. One hundred seventeen of the 141 PD-patients showed MCA levels below cutoff whereas 27 of the 35 PD+ cases showed high values. The difference in the incidence of elevated MCA levels between PD- and PD+ groups was statistically significant (p < 0.05). The overall diagnostic efficacy of MCA assays showed 77% sensitivity and 82% specificity.
Günes
I
I
Department of Nuclear Medicine, Uludağ University Hospital, Bursa, Turkey.
Miserez
A R
AR
Müller-Brand
J
J
Maecke
H
H
D000328:Adult; D000951:Antigens, Neoplasm / Q000097:blood*; D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor / Q000097:blood* / Q000276:immunology; D001943:Breast Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000556:secondary; D003951:Diagnostic Errors; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008875:Middle Aged; D011379:Prognosis
D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor; C057387:mucinous carcinoma-associated antigen