[DNA index of colorectal carcinoma and follow-up].
In relation to DNA index we have studied 18 cases of differently evoluted carcinoma of the colon, some incoherently (8) other in agreement (10) with staging. Static and flow cytometric techniques have been employed, the first by means of densitometric study on paraffin sections with the Feulgen method, the second based on application of Hedley method on paraffin included material. DNA content, pressed by the DNA index, is inversely proportional to survival with similar results in both techniques, from which the possible prognostic significance is argued.
Grigolato
P
P
Cattedra di anatomia e istologia patologica, Università di Brescia.
Chioda
C
C
Salerni
B
B
De Nobili
U
U
Nascimbeni
R
R
Lojacono
L
L
Verardi
R
R
D002277:Carcinoma / Q000737:chemistry* / Q000235:genetics / Q000401:mortality; D015179:Colorectal Neoplasms / Q000737:chemistry* / Q000235:genetics / Q000401:mortality; D004396:Coloring Agents; D004273:DNA, Neoplasm / Q000032:analysis*; D003720:Densitometry; D005260:Female; D005434:Flow Cytometry; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011123:Polyploidy; D011379:Prognosis; D012394:Rosaniline Dyes; D016019:Survival Analysis
D004396:Coloring Agents; D004273:DNA, Neoplasm; C007722:Feulgen stain; D012394:Rosaniline Dyes
DNA index del carcinoma colon-rettale e follow-up.