[Potential cardiotonics. 16. Molecular and crystal structures of three polymorphic forms and a hydrochloride monohydrate of 3-cyano-2-morpholino-5-(pyridin-4-yl)pyridine (AWD 122-14)].
The results of an X-ray structure analysis of the alpha-modification were the starting point for the prediction and establishment of further polymorphic and pseudopolymorphic, respectively, forms of AWD 122-14. A complete structure determination of the gamma- and delta-modifikation as well as of a hydrochloride monohydrate could be carried out. Molecular parameters, conformational flexibility, and intermolecular interactions are discussed in this paper.
Reck
G
G
Bundesanstalt für Materialforschung und-prüfung.
Hagen
V
V
Bannier
G
G
D002316:Cardiotonic Agents / Q000138:chemical synthesis* / Q000737:chemistry; D003460:Crystallization; D008968:Molecular Conformation; D009025:Morpholines / Q000138:chemical synthesis* / Q000737:chemistry; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry; D014961:X-Ray Diffraction
D002316:Cardiotonic Agents; D009025:Morpholines; D011725:Pyridines; C077469:3-cyano-2-morpholino-5-(pyrid-4-yl)pyridine
Potentielle Kardiotonika. 16. Mitteilung3: Molekül-und Kristallstrukturen dreier polymorpher Formen und eines Hydrochlorid-Monohydrates von 3-Cyan-2-morpholino-5-(pyrid-4-yl) pyridin (AWD 122-14).