Biology and therapy of glial tumors.
Glial tumors remain challenging problems for the clinician and researcher. Despite more aggressive therapy, the majority of these tumors recur locally. This review will provide an update on the new strategies being developed to treat gliomas. Advances in our understanding of the biology of glial tumors will provide new targets at which to direct therapy.
Weingart
J
J
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Brem
H
H
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001812:Blood-Brain Barrier / Q000187:drug effects / Q000528:radiation effects; D001932:Brain Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy*; D002330:Carmustine / Q000008:administration & dosage; D002455:Cell Division / Q000187:drug effects / Q000528:radiation effects; D002470:Cell Survival / Q000187:drug effects / Q000528:radiation effects; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D005910:Glioma / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D006801:Humans
D000970:Antineoplastic Agents; D002330:Carmustine