A re-evaluation of the tissue-specific pattern of expression of the rat kallikrein gene family.
We have used reverse transcriptase-polymerase chain reaction (RT-PCR) analysis and insitu hybridization to further define the tissue and cell-specific pattern of expression of the rat kallikrein gene family. rKlk1 gene expression has been unequivocally demonstrated in the rat heart, ovary and testis. Similarly, rKlk3, 4 and 9 gene expression has been demonstrated in the testis/ovary, heart and testis respectively. Insitu hybridization has identified the expression of kallikrein gene family members to specific cell-types in the rat ovary (granulosa cell) and testis (germ cell).
Clements
J
J
Prince Henry's Institute of Medical Research, Clayton, Victoria, Australia.
Mukhtar
A
A
Ehrlich
A
A
Fuller
P
P
D000818:Animals; D005091:Exons; D005260:Female; D015870:Gene Expression; D017403:In Situ Hybridization; D007610:Kallikreins / Q000235:genetics*; D008297:Male; D005810:Multigene Family; D010053:Ovary / Q000378:metabolism; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger / Q000235:genetics; D051381:Rats; D013737:Testis / Q000378:metabolism; D014018:Tissue Distribution
D012333:RNA, Messenger; D007610:Kallikreins