title: Oral conditions in individuals with selective immunoglobulin A deficiency and common variable immunodeficiency.
abstract: Saliva and serum samples were collected from 36 individuals with selective immunoglobulin A deficiency (IgAd) and 23 patients with common variable immunodeficiency (CVI). The oral examination included registration of the teeth, Russell's periodontal index (PI), pocket formation, and salivary flow rate in both unstimulated and stimulated saliva. No differences were found in salivary flow rate, number of teeth, or pocket depth when donors with IgAd or CVI were compared to age and sex matched controls. However, mucosal manifestations of lichenoid type were more frequent in both types of immunoglobulin deficient individuals. An increased PI was also seen in CVI patients. Increased serum IgG and salivary IgM levels were found in the IgAd population.
authors: Department of Periodontology, Karolinska Institute, Huddinge Hospital, Sweden.
authors: G N
authors: GN
authors: Engström
authors: P E
authors: PE
authors: Engström
authors: L
authors: L
authors: Hammarström
authors: C I
authors: CI
authors: Smith
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000418:Albumins / Q000032:analysis; D016022:Case-Control Studies; D003126:Colostrum / Q000276:immunology; D017074:Common Variable Immunodeficiency / Q000150:complications* / Q000276:immunology; D005260:Female; D006801:Humans; D017098:IgA Deficiency / Q000150:complications* / Q000276:immunology; D007070:Immunoglobulin A / Q000097:blood; D007071:Immunoglobulin A, Secretory / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis / Q000097:blood; D007075:Immunoglobulin M / Q000032:analysis / Q000097:blood; D007136:Immunoglobulins / Q000032:analysis / Q000097:blood; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000150:complications* / Q000276:immunology; D009066:Mouth, Edentulous / Q000150:complications; D010510:Periodontal Diseases / Q000150:complications* / Q000276:immunology; D012463:Saliva / Q000737:chemistry / Q000276:immunology / Q000378:metabolism; D012636:Secretory Rate
chemical_list: D000418:Albumins; D007070:Immunoglobulin A; D007071:Immunoglobulin A, Secretory; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins