[Changes in spinal evoked potentials caused by spinal blood flow obstruction and acidosis].
The effects of partial obstruction of blood flow and mixed type acidosis on the conduction spinal evoked potentials (C-SEP) were studied in cats anaesthetized with sodium pentobarbitone and immobilized with d-tubocurarine. Following the ligation of some intercostal arteries, changes in the C-SEP occurred: the amplitudes showed either an increase or a decrease, while the latencies were uniformly prolonged. Mixed-type acidosis resulting from a decrease in the respiratory minute volume led to a decrease in the amplitudes and an increase in the latencies. The above findings indicate that not only mechanical (obstruction of the blood flow) but also metabolic (mixed-type) factors lead to changes in the C-SEP. It is therefore important to take these factors into account and the waveform of the C-SEP should be interpreted in terms of amplitude and latency.
Kawai
M
M
Department of Emergency and Critical Care Medicine, Nippon Medical School, Tokyo, Japan.
D000138:Acidosis / Q000209:etiology*; D000784:Aortic Dissection / Q000503:physiopathology; D000818:Animals; D001014:Aortic Aneurysm / Q000503:physiopathology; D002415:Cats; D004558:Electric Stimulation; D005071:Evoked Potentials; D006801:Humans; D007511:Ischemia / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011930:Reaction Time; D012039:Regional Blood Flow / Q000502:physiology; D013116:Spinal Cord / Q000098:blood supply* / Q000502:physiology*