[The characteristics of the lipid peroxidation processes in patients with glomerulonephritis and a hematuric component].
A study of 86 patients with glomerulonephritis, urinary syndrome, presence of the hematuric component is characterized by an activation of lipid peroxidation as a result of disbalance the antioxidant system, that causes corresponding changes in the lipid phase of the cell membranes, reduction of the phospholipid and cholesterol level in the membranes, increase of its deformability capacity that may be of significance for the development of the hematuric component in patients with glomerulonephritis. The data stimulate the necessity of searching treatment directed to reduction of lipid peroxidation activation, normalization of the antioxidant system, stabilization of renal cell membranes.
Dudar
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Kolesnyk
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Nikulina
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D000975:Antioxidants; D004910:Erythrocyte Membrane / Q000378:metabolism; D005921:Glomerulonephritis / Q000097:blood* / Q000150:complications; D006417:Hematuria / Q000097:blood* / Q000209:etiology; D006801:Humans; D015227:Lipid Peroxidation; D008315:Malondialdehyde / Q000097:blood; D009404:Nephrotic Syndrome / Q000097:blood / Q000209:etiology; D010743:Phospholipids / Q000097:blood; D011507:Proteinuria / Q000097:blood / Q000209:etiology; D013482:Superoxide Dismutase / Q000097:blood
D000975:Antioxidants; D010743:Phospholipids; D008315:Malondialdehyde; D013482:Superoxide Dismutase
Osoblyvosti protsesiv perekysnoho okyslennia lipidiv u khvorykh na hlomerulonefryt z hematurychnym komponentom.