Successful treatment of musk ketone-induced chronic actinic dermatitis with cyclosporine and PUVA.
We describe a patient with chronic actinic dermatitis whose photopatch tests revealed reactions to musk ketone and musk ambrette, both of which were found in his aftershave lotion. Minimal erythema doses of UVA and UVB were decreased. After initial unsuccessful treatment with PUVA therapy the patient was successfully treated with a combination of cyclosporine and PUVA.
Gardeazábal
J
J
Department of Dermatology, Hospital de Cruces, University of the Basque Country, Bilbao, Vizcaya, Spain.
Arregui
M A
MA
Gil
N
N
Landa
N
N
Ratón
J A
JA
Diáz-Pérez
J L
JL
D002908:Chronic Disease; D016572:Cyclosporine / Q000008:administration & dosage / Q000627:therapeutic use*; D004136:Dinitrobenzenes / Q000009:adverse effects*; D004359:Drug Therapy, Combination; D006801:Humans; D007659:Ketones / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011701:PUVA Therapy; D010476:Perfume / Q000009:adverse effects*; D010787:Photosensitivity Disorders / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology
D004136:Dinitrobenzenes; D007659:Ketones; D010476:Perfume; C020422:musk ambrette (artificial); D016572:Cyclosporine