Bilateral renal artery occlusion in a patient with primary antiphospholipid antibody syndrome: thrombosis, vasculitis or both?
A 43-year-old man presented with oliguria and hypertension. Renal arteriography showed bilateral renal artery occlusion. Circulating antiphospholipid antibodies were found together with a change in natural anticoagulant plasma levels. Immunofluorescence of examined vessels showed immune complex vasculitis. We discuss the pathogenetic mechanism leading to the development of this rare occlusive event.
Ames
P R
PR
Institute of Internal Medicine and Metabolic Diseases, 2nd Medical School, University of Naples, Italy.
Cianciaruso
B
B
Bellizzi
V
V
Balletta
M
M
Lubrano
E
E
Scarpa
R
R
Brancaccio
V
V
D000328:Adult; D000792:Angiography; D017152:Antibodies, Antiphospholipid / Q000032:analysis; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000175:diagnosis; D005455:Fluorescent Antibody Technique; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000032:analysis; D008297:Male; D012078:Renal Artery Obstruction / Q000150:complications* / Q000175:diagnosis; D013927:Thrombosis / Q000150:complications* / Q000175:diagnosis; D014657:Vasculitis / Q000150:complications* / Q000175:diagnosis
D017152:Antibodies, Antiphospholipid; D016682:Lupus Coagulation Inhibitor