Maxillary antrum involvement in multibacillary leprosy: a radiologic, sinuscopic, and histologic assessment.
Thirty patients having lepromatous leprosy (22 males, 8 females) and showing radiological involvement of the maxillary antrum were subjected to sinuscopy, biopsy, and histopathological examination. Radiological observations showed diffuse opacity in 33.3% of the sinuses, localized mucosal thickening in 28.6%, and generalized thickened mucosa in 38.1%. Sinuscopy revealed inflamed mucosa as the most common finding (40%), followed by ulcerative (26.7%) and granulomatous (10%) lesions of the mucosal lining. The mucosal thickening (localized or generalized) evident on radiology was always associated with granuloma formation and acid-fast bacilli in the histology. The presence of an external nasal deformity indicated a statistically significant chance of encountering mucosal involvement on sinuscopy and histopathology (p < 0.05). There was more chance of finding positive sinuscopic lesions in those patients with a bacterial index above 3+.
Hauhnar
C Z
CZ
Department of Otorhinolaryngology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Mann
S B
SB
Sharma
V K
VK
Kaur
S
S
Mehta
S
S
Radotra
B D
BD
D000328:Adult; D001706:Biopsy; D004724:Endoscopy; D005260:Female; D006801:Humans; D015440:Leprosy, Lepromatous / Q000175:diagnosis*; D008297:Male; D015523:Maxillary Sinusitis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology; D009297:Nasal Mucosa / Q000473:pathology; D011859:Radiography