[Biodemographic parameters as indicators of genetic adaptation to harmful occupational factors (e.g. asbestos)].
A total of 129 women working at asbestos-concentrating factories and asbestos articles manufacture plant, including 87 of them facing asbestosis and 42 exposed to asbestos without asbestosis were examined. There was no marked shifts in the reproductive function and pregnancy results of women facing asbestosis and those exposed to asbestos without asbestosis. Women facing asbestosis has infant mortality higher than other women. Parameters of potential selection (index Crow) in the studied population showed an unfavourable demographic situation in women facing asbestosis. Analysis of biodemographic data helped to suggest the possibility of genetic predisposition to asbestosis.
Tsurikova
G V
GV
Spitsyn
V A
VA
Gladkova
E V
EV
Minaeva
O P
OP
D000022:Abortion, Spontaneous / Q000209:etiology* / Q000235:genetics; D000220:Adaptation, Biological / Q000235:genetics; D000328:Adult; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D001194:Asbestos / Q000009:adverse effects*; D001195:Asbestosis / Q000150:complications* / Q000235:genetics; D004198:Disease Susceptibility; D005260:Female; D005838:Genotype; D006801:Humans; D007223:Infant; D007226:Infant Mortality; D007231:Infant, Newborn; D007247:Infertility, Female / Q000209:etiology* / Q000235:genetics; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D012426:Russia
D000395:Air Pollutants, Occupational; D001194:Asbestos
Biodemograficheskie pokazateli kak indikatory geneticheskoĭ adaptatsii k vrednomu proizvodstvennomu vozdeĭstviiu (na primere asbesta).