[Hemostatic changes in patients with pulmonary tuberculosis in the postoperative period in relation to the volume of surgical blood loss].
Hemocoagulation changes were studied in 71 pulmonary tuberculosis patients in the postoperative period. Red blood parameters and graphic coagulogram were determined. A moderate hypercoagulation syndrome was found in patients with operative blood loss of 500 g in the early and immediate postoperative period. With a rise in the operative blood loss volume and hemodilution degree changes appeared indicating a tendency to hypocoagulation shifts. In patients having moderate blood loss (501-1500 g) the hypocoagulation syndrome was associated with dilution coagulopathy. In larger blood loss (over 1500 g) the hypocoagulation syndrome was aggravated both by hemodilution coagulopathy and the expenditure of blood coagulation factors with the increase in fibrinolytic blood activity. These cases require therapy aimed at the prevention and management of arising hemocoagulation disorders.
Sinitsyn
M A
MA
Minina
M N
MN
D000293:Adolescent; D000328:Adult; D000368:Aged; D001777:Blood Coagulation / Q000502:physiology*; D001780:Blood Coagulation Tests / Q000379:methods; D016063:Blood Loss, Surgical; D001810:Blood Volume / Q000502:physiology*; D001811:Blood Volume Determination / Q000379:methods; D004906:Erythrocyte Count; D006488:Hemostasis, Surgical; D006801:Humans; D008875:Middle Aged; D010976:Platelet Count; D011013:Pneumonectomy; D011184:Postoperative Period; D013997:Time Factors; D014397:Tuberculosis, Pulmonary / Q000503:physiopathology*
Izmeneniia sostoianiia gemostaza u ftiziokhirurgicheskikh bol'nykh v posleoperatsionnom periode v zavisimosti ot ob''ema operatsionnoĭ krovopoteri.