Advances in monoclonal antibody therapy of cancer.
Tumor-associated antigens can be seen as unique targets for the delivery of anti-cancer therapy. Monoclonal antibodies directed at such antigens are increasingly being seen as important biologic reagents that will complement the group of existing cytotoxic drugs. This report briefly overviews recent advances in the field of monoclonal antibody therapy of cancer and provides insight regarding the promises and limitations of this novel therapeutic approach.
LoBuglio
A F
AF
University of Alabama, Comprehensive Cancer Center, Birmingham 35294-3300.
Saleh
M N
MN
D000818:Animals; D000911:Antibodies, Monoclonal / Q000235:genetics / Q000627:therapeutic use*; D005260:Female; D005818:Genetic Engineering; D006801:Humans; D000922:Immunotoxins / Q000627:therapeutic use*; D008223:Lymphoma / Q000628:therapy; D009369:Neoplasms / Q000628:therapy*; D016499:Radioimmunotherapy
D000911:Antibodies, Monoclonal; D000922:Immunotoxins