title: [Degradation of endo- and exogenous albumin in normal and starved rats].
abstract: A rate of degradation of homologous exogenous 14C-albumin proved to be higher 3-fold as compared with that of endogenous 14C-albumin, while the albuminolysis rate was additionally increased in starvation. Evaluation of 14C- and 3H-labels demonstrated that the protein hydrolysis occurred mainly in liver tissue, kidney and intestinal membrane and its rate was elevated in starvation. Dissimilar secretion of exo- and endogenous albumins into small intestine lumen was detected. Removal of albumins was found to depend on augmentation in the proteolytic potential and on reconstructive activity of secondary lysosomes.
authors: G Iu
authors: GIu
authors: Mal'tsev
authors: A V
authors: AV
authors: Vasil'ev
mesh_terms: D000418:Albumins / Q000378:metabolism*; D000818:Animals; D002250:Carbon Radioisotopes; D010450:Endopeptidases / Q000378:metabolism; D006868:Hydrolysis; D007413:Intestinal Mucosa / Q000378:metabolism; D008099:Liver / Q000201:enzymology / Q000378:metabolism; D008247:Lysosomes / Q000201:enzymology; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013217:Starvation / Q000378:metabolism*
chemical_list: D000418:Albumins; D002250:Carbon Radioisotopes; D010450:Endopeptidases
vernacular_title: Issledovanie degradatsii éndo- i ékzogennogo al'bumina u normal'nykh i golodnykh krys.