Sphingofungins E and F: novel serinepalmitoyl transferase inhibitors from Paecilomyces variotii.
Horn
W S
WS
Merck Research Laboratories, Rahway, N.J. 07065.
Smith
J L
JL
Bills
G F
GF
Raghoobar
S L
SL
Helms
G L
GL
Kurtz
M B
MB
Marrinan
J A
JA
Frommer
B R
BR
Thornton
R A
RA
Mandala
S M
SM
D000217:Acyltransferases / Q000037:antagonists & inhibitors*; D000596:Amino Acids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D005231:Fatty Acids, Unsaturated / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005658:Fungi / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008828:Microbiological Techniques; D010143:Paecilomyces / Q000737:chemistry* / Q000502:physiology; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000201:enzymology; D051102:Serine C-Palmitoyltransferase
D000596:Amino Acids; D000935:Antifungal Agents; D005231:Fatty Acids, Unsaturated; C078943:sphingofungin E; C078944:sphingofungin F; D000217:Acyltransferases; D051102:Serine C-Palmitoyltransferase