[Characteristics of thrombocyte metabolism in puerperae with massive blood loss and gestosis and possible ways of its metabolic correction].
Succinate dehydrogenase, phospholipid and glycogen activities were measured by cytochemical methods in puerperae with massive blood loss in the presence of gestosis in order to investigate platelet metabolism and the possible approaches to metabolic correction. A significant depression of platelet intracellular metabolism was revealed in these puerperae. Metabolic correction agents (acetyl salicylic acid, essential, alpha-tocopherol, retinol) were added to routine intensive therapy. The treatment was conducive to normalization of the metabolic processes and rapid recovery of puerperae with massive blood loss developing in the presence of gestosis.
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D001241:Aspirin / Q000008:administration & dosage; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism*; D004338:Drug Combinations; D005260:Female; D006003:Glycogen / Q000097:blood; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects / Q000502:physiology; D010743:Phospholipids / Q000097:blood; D006473:Postpartum Hemorrhage / Q000097:blood* / Q000209:etiology; D011225:Pre-Eclampsia / Q000097:blood* / Q000150:complications; D011247:Pregnancy; D013385:Succinate Dehydrogenase / Q000097:blood / Q000172:deficiency; D014801:Vitamin A / Q000008:administration & dosage; D014810:Vitamin E / Q000008:administration & dosage
D004338:Drug Combinations; D010743:Phospholipids; D014801:Vitamin A; D014810:Vitamin E; C048974:vitamin A, vitamin E drug combination; D006003:Glycogen; D013385:Succinate Dehydrogenase; D001241:Aspirin
Osobennosti metabolizma trombotsitov u rodil'nits s massivnoĭ krovopotereĭ na fone gestoza i vozmozhnye puti metabolicheskoĭ korrektsii.