Stochastic models of lesion induction and repair in yeast.
In the past decade several stochastic models for the effects of radiation on cell survival have been proposed. We survey them briefly and consider their possible application to some experimental results of Frankenberg-Schwager and co-authors on irradiated yeast. One possible model is a slight modification of the model proposed by Yang and Swenberg. It is shown that the modified model does not actually fit well and that the repair mechanism requires additional complications for adequate description.
Le Cam
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Department of Statistics, University of California, Berkeley 94720.
D004260:DNA Repair / Q000528:radiation effects; D004271:DNA, Fungal / Q000528:radiation effects; D008954:Models, Biological; D015233:Models, Statistical; D012441:Saccharomyces cerevisiae / Q000528:radiation effects*; D013269:Stochastic Processes
D004271:DNA, Fungal