Risk factors in postoperative neurosurgical infection. A prospective study.
Four hundred and seventy patients who had undergone neurosurgical operations were studied prospectively. After defining post-operative infection so that is included all the infective complications irrespective of location occurring after surgery, the overall infection rate was 17%. The infection rate in 413 cases without pre-existing infection was 15%. Wound infection was recorded in 5% and meningitis in 6%. Risk factors which lead to a significant increase in the incidence of postoperative infection were found to be altered sensorium, multiple operations, pre-existing infection, emergency surgery, duration of surgery more than 4 hours, urinary catheterisation, cerebrospinal fluid leak, and ventilatory support.
Patir
R
R
Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi.
Mahapatra
A K
AK
Banerji
A K
AK
D000284:Administration, Oral; D001424:Bacterial Infections / Q000209:etiology* / Q000517:prevention & control; D002439:Cefotaxime / Q000008:administration & dosage; D002493:Central Nervous System Diseases / Q000601:surgery*; D002506:Cephalexin / Q000008:administration & dosage; D002557:Cerebrospinal Fluid Shunts; D003428:Cross Infection / Q000209:etiology* / Q000517:prevention & control; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D016920:Meningitis, Bacterial / Q000209:etiology / Q000517:prevention & control; D008875:Middle Aged; D010406:Penicillins / Q000008:administration & dosage; D011292:Premedication; D011446:Prospective Studies; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000209:etiology* / Q000517:prevention & control
D005839:Gentamicins; D010406:Penicillins; D002439:Cefotaxime; D002506:Cephalexin