title: [Plasma interleukin-6 in patients with disseminated intravascular coagulation].
abstract: Plasma Interleukin-6 (IL-6) level was measured in 60 patients with disseminated intravascular coagulation (DIC). Plasma IL-6 level was high in patients with DIC, and was particularly high in patients with multiple organ failure (MOF) or poor prognosis. Plasma IL-6 level correlated positively with C-reactive protein in patients without DIC, but not in those with DIC. The increased plasma IL-6 level observed in DIC patients suggests that activation of the immune system is involved in the progression of DIC and in the pathology of organ failure.
authors: 2nd Department of Internal Medicine, Mie University School of Medicine.
authors: K
authors: K
authors: Minamikawa
authors: H
authors: H
authors: Wada
authors: M
authors: M
authors: Ohiwa
authors: T
authors: T
authors: Kaneko
authors: T
authors: T
authors: Tsukada
authors: S
authors: S
authors: Kageyama
authors: T
authors: T
authors: Kobayashi
authors: M
authors: M
authors: Tomeoku
authors: M
authors: M
authors: Katou
authors: N
authors: N
authors: Minami
mesh_terms: D000328:Adult; D002097:C-Reactive Protein / Q000378:metabolism; D004211:Disseminated Intravascular Coagulation / Q000097:blood* / Q000276:immunology; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D008297:Male; D009102:Multiple Organ Failure / Q000097:blood; D011379:Prognosis
chemical_list: D015850:Interleukin-6; D002097:C-Reactive Protein