Associated polyneuropathy and demyelinating disease. Case report.
We report a case in which an acute Guillain-Barré-like syndrome was quickly followed by a central demyelinating disease, documented by the clinical findings as well as by magnetic resonance imaging (MRI), electrophysiological and cerebrospinal fluid examinations. The close follow-on of the clinical signs seems to exclude a simple coincidence of two separate diseases and it may constitute further evidence for a possible etiological link between central and peripheral myelin damage. We discuss the possibility of a common pathogenic factor underlying central and peripheral demyelination.
Rebaudengo
N
N
Dipartimento di Neurologia, Università di Torino.
Bianco
C
C
Ferrero
P
P
Troni
W
W
Bergamasco
B
B
D000161:Acoustic Stimulation; D000293:Adolescent; D003711:Demyelinating Diseases / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology; D005074:Evoked Potentials, Visual / Q000502:physiology; D006801:Humans; D008297:Male; D010775:Photic Stimulation; D011129:Polyradiculoneuropathy / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D011930:Reaction Time / Q000502:physiology