title: [Expandable metallic stent therapy for SVC syndrome--effects on local venous pressure, vascular diameter, symptoms, and these correlations].
abstract: To evaluate the efficacy of Z-stent therapy for SVC syndrome, we studied changes in the pressure, the diameter of stenotic lumen and the symptoms in the cases of SVC syndrome with higher pressure than 30 cmH2O at distal to the stenosis. The symptoms were classified and graded to be scored up. Immediately after the Z-stent placement into the stenotic lesions, the venous pressure distal to the stenosis decreased from 36.0 +/- 3.4 cmH2O to 12.0 +/- 12.0 cmH2O (p < 0.001), the diameter of stenotic lumen increased from 3.3 +/- 3.4 mm to 14.0 +/- 3.4 mm (p < 0.01). According to the remarkable symptomatic improvements the averaged score decreased from 6.7 to 1.3 (p < 0.01). The pressure, the diameter and the symptom scores were highly correlated each other (magnitude of gamma not equal to 0.9). Among two cases with the right atrial pressure increase by 2 cmH2O after the placement one suffered transient cardiac in compensation due to overload by reperfusion. Conclusively, the Z-stent therapy was very effective on the SVC syndrome in reducing abnormally elevated venous pressure due to the stenosis, and relieving the symptoms, while the pressure monitor was necessary.
authors: Department of Radiology, Saiseikai Wakayama Hp.
authors: K
authors: K
authors: Kishi
authors: T
authors: T
authors: Sonomura
authors: K
authors: K
authors: Mitsuzane
authors: N
authors: N
authors: Nishida
authors: R J
authors: RJ
authors: Yang
authors: S
authors: S
authors: Nomura
authors: M
authors: M
authors: Satoh
authors: R
authors: R
authors: Yamada
authors: H
authors: H
authors: Kobayashi
authors: M
authors: M
authors: Juri
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015607:Stents; D013479:Superior Vena Cava Syndrome / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D014683:Vena Cava, Superior / Q000473:pathology / Q000503:physiopathology; D014690:Venous Pressure / Q000502:physiology