Locally invasive aspergillosis of the bowel.
Locally invasive aspergillosis of the bowel and peritoneal cavity is a rare complication of immunosuppression, broad-spectrum antibiotic therapy, and corticosteroid administration. We present the case of a 9-year-old boy with acute lymphocytic leukemia who presented with a small bowel obstruction. Surgical treatment of the aspergillosis required multiple aggressive resections of all involved bowel segments. Parenteral nutrition and intravenous Amphotericin B and 5-Fluorocytosine therapy were also instituted. Achievement of a hematologic remission is another prerequisite for cure.
Marterre
W F
WF
Department of Surgery, University of Kentucky Medical Center, Lexington 40536-0084.
Mong
A T
AT
Pulito
A R
AR
D001228:Aspergillosis / Q000150:complications / Q000473:pathology / Q000628:therapy; D002648:Child; D006801:Humans; D016867:Immunocompromised Host; D007410:Intestinal Diseases / Q000382:microbiology / Q000473:pathology / Q000628:therapy; D007415:Intestinal Obstruction / Q000209:etiology; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000276:immunology