Kinetics of serum levels of interleukin-6 in Staphylococcus aureus septicemia.
The kinetics of Il-6 serum concentrations were analyzed in 17 patients with a culture verified Staphylococcus aureus septicemia. The analyses were performed using an antigen capture immunoassay. All patients had elevated IL-6 serum concentrations on admission. In most cases a subsequent rapid decrease to low levels was registered within 10 days. The IL-6 serum concentrations reflected the clinical course. In sera sampled on admission a relationship was found between IL-6 serum concentrations and levels of C-reactive protein.
Söderquist
B
B
Department of Infectious Diseases, Orebro Medical Center Hospital, Sweden.
Sundqvist
K G
KG
Vikerfors
T
T
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000097:blood*; D002097:C-Reactive Protein / Q000032:analysis; D002648:Child; D005260:Female; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011446:Prospective Studies; D013203:Staphylococcal Infections / Q000097:blood*; D013211:Staphylococcus aureus
D015850:Interleukin-6; D002097:C-Reactive Protein