[Acid-base equilibrium and blood gases in pregnant women with habitual abortion after metabolic therapy].
Blood oxygen transport, pH, acid-base status, urinary ketone level and urobilinogen were studied in 52 pregnant women in whom pregnancy ran a normal course and in 56 ones with a history of habitual abortions, treated for metabolic disorders. Signs of metabolic acidosis in the presence of respiratory alkalosis at the expense of pulmonary hyperventilation were detected in women with normal pregnancy. Follow-up of acid-base status and gases of blood, aciduria and ketonuria in pregnant women with a history of habitual abortions has revealed in them respiratory alkalosis signs presenting in hypoxemia and reduced oxygen saturation and ketonuria. Metabolic therapy included in combined therapeutic schemes for such patients actively influenced the processes of metabolic acidosis and ketonuria compensation, probably at the expense of its normalizing effect on intracellular metabolism. Metabolic therapy of pregnant women liable to spontaneous abortions, due to ovarian hypofunction had a marked antihypoxic effect, normalized the bicarbonate system status and was therefore conducive to improvement of oxygen transport to maternal tissues and the fetus.
Burlev
V A
VA
Mamedalieva
N M
NM
Sidel'nikova
V M
VM
D000026:Abortion, Habitual / Q000150:complications / Q000188:drug therapy / Q000378:metabolism*; D000136:Acid-Base Equilibrium / Q000187:drug effects / Q000502:physiology*; D000138:Acidosis / Q000188:drug therapy / Q000209:etiology*; D000328:Adult; D002245:Carbon Dioxide / Q000097:blood*; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D010100:Oxygen / Q000097:blood*; D011247:Pregnancy; D013835:Thiamine Pyrophosphate / Q000008:administration & dosage; D008063:Thioctic Acid / Q000008:administration & dosage; D014801:Vitamin A / Q000008:administration & dosage; D014810:Vitamin E / Q000008:administration & dosage
D004338:Drug Combinations; D014801:Vitamin A; D014810:Vitamin E; D002245:Carbon Dioxide; C048974:vitamin A, vitamin E drug combination; D008063:Thioctic Acid; D013835:Thiamine Pyrophosphate; D010100:Oxygen
Kislotno-osnovnoe sostoianie i gazy krovi u beremennykh s privychnym nevynashivaniem na fone metabolicheskoĭ terapii.