Physico-chemical modeling of the role of free radicals in photo-dynamic therapy. I. Utilization of quantum yield data of singlet oxygen formation for the study of the interaction between excited photosensitizer and stable free radicals.
The measurement of the relative quantum yield of singlet oxygen formation, a simple process without tedious sample deoxygenation, is shown to furnish data on the interaction of the excited photosensitizer with any additive (in this case stable free radicals) given to the sample. The rate constants derived from such measurements are in good agreement with direct determination of the corresponding values.
Vidóczy
T
T
Central Research Institute for Chemistry, Hungarian Academy of Sciences, Budapest.
Elzemzam
S
S
Gál
D
D
D005609:Free Radicals; D006415:Hematoporphyrins / Q000737:chemistry*; D007700:Kinetics; D010100:Oxygen; D010777:Photochemistry; D010778:Photochemotherapy; D011789:Quantum Theory; D011838:Radiation-Sensitizing Agents / Q000737:chemistry*; D026082:Singlet Oxygen
D005609:Free Radicals; D006415:Hematoporphyrins; D011838:Radiation-Sensitizing Agents; D026082:Singlet Oxygen; D010100:Oxygen