DNA reactive and epigenetic carcinogens.
Animal and human carcinogens exert their effects through diverse mechanisms which include DNA reaction and epigenetic effects. This review covers the basis for distinguishing between carcinogens that have either DNA reactivity or epigenetic activity as their primary effect.
Williams
G M
GM
Division of Pathology and Toxicology, American Health Foundation, Valhalla, NY 10595.
D000818:Animals; D002273:Carcinogens / Q000633:toxicity*; D002477:Cells / Q000187:drug effects*; D004247:DNA / Q000187:drug effects*; D006801:Humans
D002273:Carcinogens; D004247:DNA