title: Human urokinase contains GalNAc beta (1-4)[Fuc alpha (1-3)]GlcNAc beta (1-2) as a novel terminal element in N-linked carbohydrate chains.
abstract: Structural analysis of enzymically released N-linked carbohydrate chains of human urokinase (urinary-type plasminogen activator) by 1H NMR spectroscopy and FAB-MS demonstrated that the N-linked oligosaccharides on the only N-glycosylation site contain diantennary structures with the novel GalNAc beta (1-4) [Fuc alpha (1-3)]GlcNAc beta (1-2) element in the upper or the lower branch.
authors: Bijvoet Center, Department of Bio-Organic Chemistry, Utrecht University, The Netherlands.
authors: A A
authors: AA
authors: Bergwerff
authors: J E
authors: JE
authors: Thomas-Oates
authors: J
authors: J
authors: van Oostrum
authors: J P
authors: JP
authors: Kamerling
authors: J F
authors: JF
authors: Vliegenthart
mesh_terms: D002240:Carbohydrate Sequence; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D016339:Spectrometry, Mass, Fast Atom Bombardment; D014568:Urokinase-Type Plasminogen Activator / Q000737:chemistry*
chemical_list: D014568:Urokinase-Type Plasminogen Activator