Influence of inoculation route on virulence of Rhodococcus equi in mice.
Virulence of R. equi ATCC 33701 was compared by the intraperitoneal (i.p.) and intravenous (i.v.) routes in mice. Strain ATCC 33701 was more virulent by the i.v. than the i.p. route. The LD50 of strain ATCC 33701 by either route correlated with the initial number of bacteria in the liver and spleen at day 0.
Takai
S
S
Department of Animal Hygiene, School of Veterinary Medicine and Animal Sciences, Kitasato University, Aomori, Japan.
Sasaki
Y
Y
Tsubaki
S
S
D000193:Actinomycetales Infections / Q000401:mortality / Q000662:veterinary*; D000818:Animals; D005260:Female; D007274:Injections, Intraperitoneal; D007275:Injections, Intravenous; D007928:Lethal Dose 50; D008099:Liver / Q000382:microbiology; D008168:Lung / Q000382:microbiology; D051379:Mice; D008815:Mice, Inbred Strains; D016929:Rhodococcus equi / Q000472:pathogenicity*; D013997:Time Factors; D014774:Virulence