Immunization of day-old chickens against Newcastle disease.
The avirulent Newcastle disease virus strain designated NDV-6/10, selected by B. Lomniczi at the Veterinary Medical Research Institute, Hungarian Academy of Sciences, is completely safe for day-old chickens by aerosol vaccination. Aerosol immunization using the Hungarian-made MASTERDROP generator (particle size: maximum 7 microns) caused no vaccination reactions among 206,000 chickens with different maternal antibody levels. Other vaccines given simultaneously did not significantly affect the protection elicited against Newcastle disease (ND). Almost 100% and 90% of the aerosolized chickens survived subcutaneous challenge with 10(6) LD50 NDV at 30 and 50 days old, respectively. A single immunization is sufficient for broilers; however, parent flocks should be revaccinated at 7 so 8 weeks old.
Mészáros
J
J
Veterinary Medical Research Institute, Hungarian Academy of Sciences, Budapest.
Szemerédi
M
M
Tamási
G
G
D000280:Administration, Inhalation; D000818:Animals; D002645:Chickens / Q000276:immunology*; D009521:Newcastle Disease / Q000517:prevention & control*; D011201:Poultry Diseases / Q000517:prevention & control*; D014611:Vaccination / Q000379:methods / Q000662:veterinary*