title: Cell culture of macular epiretinal membranes.
abstract: To attempt to differentiate the cells of origin in epiretinal membranes, cells were cultured from an idiopathic epiretinal membrane and an epiretinal membrane that formed after successful repair of a retinal detachment. The cells exhibited a variety of forms. When the cells from the idiopathic epiretinal membrane were incubated with melanin from donor eyes a population of small cells accumulated the pigment, but the large, flat cells did not. The epiretinal membrane was not composed of a single cell type. Although a population of cells exists within epiretinal membranes, no one cell type could be identified as the cell type of origin.
authors: Department of Ophthalmology, University of Ottawa.
authors: I M
authors: IM
authors: MacDonald
authors: C H
authors: CH
authors: Smith
authors: W A
authors: WA
authors: Britton
mesh_terms: D000368:Aged; D002478:Cells, Cultured; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D008543:Melanins / Q000378:metabolism; D008875:Middle Aged; D012160:Retina / Q000473:pathology*; D012163:Retinal Detachment / Q000473:pathology / Q000601:surgery; D014821:Vitrectomy
chemical_list: D008543:Melanins