The amount of drug remaining in the body at the time Tmax after simultaneous extravascular and intravenous administration.
When a drug is simultaneously given extravascularly and intravenously, the plasma concentration reaches a maximum at a time Tmax. The purpose of this paper is to get the amount of the drug remaining in the body at this time Tmax. Furthermore, mean residence time of the drug and the area under concentration curve are given.
Plusquellec
Y
Y
Unité de Formation et de Recherches de Mathématiques, Université Paul Sabatier, Toulouse, France.
Houin
G
G
D006801:Humans; D007267:Injections; D007275:Injections, Intravenous; D008954:Models, Biological; D010599:Pharmacokinetics