title: Efficacy of intraruminal albendazole boluses against Dicrocoelium dendriticum in sheep.
abstract: The anthelmintic potential of albendazole (ABZ) in intraruminal boluses (Proftril-Captec) was investigated in sheep harbouring naturally acquired Dicrocoelium infection. The anthelmintic efficacy was assessed by coprological testing during the autumn pasture and comparison of worm counts in 22 necropsied animals (11 treated and 11 untreated) at the end of the experiment. The mean faecal egg count (EPG) in treated animals dropped significantly during week 2, and between the 4th and the 12th week the faecal samples were almost negative. The health status of treated animals improved significantly during the first 2 weeks. Helminthological dissection of livers and small intestines revealed 91.8% efficacy, but a small number of live adult flukes were found in all treated animals.
authors: Helminthological Institute, Slovak Academy of Sciences, Kosice, Czechoslovakia.
authors: J
authors: J
authors: Corba
authors: I
authors: I
authors: Krupicer
mesh_terms: D000284:Administration, Oral; D015766:Albendazole / Q000008:administration & dosage / Q000627:therapeutic use*; D000818:Animals; D003692:Delayed-Action Preparations; D004011:Dicrocoeliasis / Q000188:drug therapy / Q000662:veterinary*; D005243:Feces / Q000469:parasitology; D005260:Female; D007421:Intestine, Small / Q000469:parasitology; D008099:Liver / Q000469:parasitology / Q000473:pathology; D010270:Parasite Egg Count / Q000662:veterinary; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy*
chemical_list: D003692:Delayed-Action Preparations; D015766:Albendazole