title: Cilia in children with recurrent upper respiratory tract infections: ultrastructural observations.
abstract: We investigated the ultrastructure of nasal cilia in 27 children suffering from recurrent infections of the upper respiratory tract, during and after the onset of an acute respiratory infection, and after a convalescent period of 12 weeks. Our results demonstrated that in seven subjects after resolution of infection, the morphology of a large proportion of the cilia (32%) was not back to normal. These findings suggest a long-term residual effect of infection, or the inability to reestablish normal ciliary structure during the convalescent period in some subjects with recurrent upper respiratory tract infection.
authors: Pediatric Clinic, University of Ancona, Italy.
authors: P L
authors: PL
authors: Giorgi
authors: N
authors: N
authors: Oggiano
authors: P C
authors: PC
authors: Braga
authors: C
authors: C
authors: Catassi
authors: O
authors: O
authors: Gabrielli
authors: G V
authors: GV
authors: Coppa
authors: A
authors: A
authors: Kantar
mesh_terms: D000208:Acute Disease; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D002923:Cilia / Q000502:physiology / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D009068:Movement; D009666:Nose / Q000648:ultrastructure*; D012008:Recurrence; D012141:Respiratory Tract Infections / Q000473:pathology*