Synthesis and antimicrobial activity of some pyrrole derivatives. V: 5-Aryl-3-ethoxycarbonyl-2-(4-substituted piperazino)pyrrole derivatives.
The synthesis of new 5-aryl-3-ethoxycarbonyl-2-piperazinopyrrole derivatives is reported. The new compounds were tested in vitro for their antimicrobial activity. Compound 11 was the most active against the Gram-positive microorganisms.
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Dipartimento Farmaco Chimico Technologico, Ospedale, Cagliari, Italy.
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D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D005658:Fungi / Q000187:drug effects; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010879:Piperazines / Q000138:chemical synthesis* / Q000494:pharmacology; D011758:Pyrroles / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D010879:Piperazines; D011758:Pyrroles