Sex determination and differentiation in invertebrates: Drosophila and Caenorhabditis elegans.
Sex determination in flies and worms is controlled by cascades beginning with the X chromosome: autosome ratio and terminating in transcription factors. We are now gaining an understanding of the molecular mechanisms governing the largely post-transcriptional regulation of the intermediate steps in these cascades.
McKeown
M
M
Molecular Biology and Virology Laboratory, Salk Institute, San Diego, California 92186.
Madigan
S J
SJ
D000818:Animals; D001483:Base Sequence; D002107:Caenorhabditis / Q000235:genetics*; D002454:Cell Differentiation / Q000502:physiology; D004330:Drosophila / Q000235:genetics*; D005786:Gene Expression Regulation / Q000502:physiology; D008969:Molecular Sequence Data; D012732:Sex Determination Analysis; D014960:X Chromosome