[Differentiation, electrically stimulated nuclear motility and ultrastructure of buccal epithelial cells from normal people and psoriatic patients].
The comparative analysis of cell differentiation, ultrastructure and volt-stimulated cell nuclear motility was made on buccal epithelium scraped from normal persons and psoriatic patients. About 70% of cells in normal epithelium were classified as cells of the 5th differentiation stage. The same percent of cells exhibited the stimulated nuclear motility. In buccal epithelium of psoriatic patients 54% of cells belonged to the 4th differentiation stage, but ultrastructurally they were of the 3-5th differentiation stages. In epithelial cells of psoriatic patients only 25% of cells were classified as the 5th differentiation stage and 34% of cells had nuclear motility. Their percent increased by 60 when 10(-7) M adrenaline was added in vitro. The results allow conclusion that the nuclear motility is characteristic of degraded epithelial cells with defective tonofilamentous cytoskeleton but with retained electrochemical K(+)-potential.
Goncharenko
M S
MS
Petruniaka
V V
VV
Ereshchenko
E A
EA
D002454:Cell Differentiation / Q000187:drug effects / Q000502:physiology; D002467:Cell Nucleus / Q000187:drug effects / Q000502:physiology*; D002610:Cheek; D004558:Electric Stimulation; D004837:Epinephrine / Q000494:pharmacology; D004848:Epithelium / Q000187:drug effects / Q000648:ultrastructure; D006801:Humans; D066298:In Vitro Techniques; D007972:Leukoplakia, Oral / Q000473:pathology*; D009061:Mouth Mucosa / Q000187:drug effects / Q000648:ultrastructure*; D012016:Reference Values
D004837:Epinephrine
Differentsirovka, élektrostimuliruemaia podvizhnost' iader i ul'trastruktura kletok v soskobakh bukkal'nogo épiteliia v norme i pri psoriaze.