Mycoplasma gallisepticum vaccination-challenge: an egg-production model.
Specific-pathogen-free layer hens in maximum lay were exposed by aerosol to a broth culture of Mycoplasma gallisepticum R' strain. Egg-production loss of greater than 50% was evident 7-14 days following challenge of unvaccinated chickens, with a gradual recovery during the next several days. Various vaccine preparations were tested to determine the effect in the model. All vaccinated chickens exhibited significantly (P < or = 0.05) lower egg-production loss than the unvaccinated controls. The model provides a method for testing treatment effects on egg-production losses resulting from controlled exposure to M. gallisepticum and may be useful in simulating field exposure.
Evans
R D
RD
Department of Human Ecology, School of Agricultural Sciences, University of Maryland Eastern Shore, Princess Anne 21853.
Hafez
Y S
YS
Orthel
F W
FW
D000818:Animals; D001428:Bacterial Vaccines / Q000276:immunology*; D002645:Chickens / Q000276:immunology / Q000382:microbiology / Q000502:physiology*; D004531:Eggs; D005260:Female; D008954:Models, Biological; D009174:Mycoplasma / Q000276:immunology*; D009175:Mycoplasma Infections / Q000503:physiopathology / Q000517:prevention & control / Q000662:veterinary*; D011201:Poultry Diseases / Q000382:microbiology / Q000503:physiopathology* / Q000517:prevention & control; D013223:Statistics as Topic
D001428:Bacterial Vaccines