title: [Prehospital fibrinolysis: a priority objective?].
abstract: Clinical trials strongly suggest that the sooner thrombolysis is applied after the onset of chest pain, the greater are the derived benefits. Time delay between onset chest pain and initiation of therapy possesses three fundamental components: 1) the call for help; 2) the transportation to the hospital, and 3) the in-hospital delay for diagnosis and initiation of therapy. On the other hand, pre-hospital thrombolysis has been shown feasible and safe; more importantly, it has resulted in early identification of patients eligible for fibrinolysis, greatly accelerating the process of drug administration. A critical look at all measures that could result in more rapid treatment is now indicated. This include early identification of eligible patients, prompt clinical and electrocardiographic diagnosis, rapid transportation to hospital and undelayed drug administration by competent personnel. Every clinical center should investigate the practice in its community area to detect where, when and why time is lost between onset of pain and treatment application to institute the appropriate corrective measures.
authors: Departamento de Medicina, Montreal Heart Institute, Quebec, Canadá.
authors: R M
authors: RM
authors: Lidón
authors: P
authors: P
authors: Théroux
mesh_terms: D002986:Clinical Trials as Topic; D004632:Emergency Medical Services; D006801:Humans; D015337:Multicenter Studies as Topic; D009203:Myocardial Infarction / Q000188:drug therapy*; D015912:Thrombolytic Therapy; D013997:Time Factors
vernacular_title: Fibrinólisis prehospitalaria: objetivo prioritario?