[Primary neuroendocrine cutaneous carcinoma or Merkel cell carcinoma. Review of the literature].
The neuroendocrine carcinomas of the skin, also called Merkel cell carcinomas, are unusual malignancies mostly observed in the elderly. They are diagnosed by a pathologist: ultrastructural studies and immunohistochemistry support the diagnosis. The prognosis is poor. Lymph nodes and metastases quickly arise although sometimes, they are discovered immediately. A combination of surgery and radiotherapy is recommended. Metastases and unresectable tumors should be treated by chemotherapy.
Atlan
D
D
Service d'oncologie médicale, centre Henri-Becquerel, Rouen, France.
Chevallier
B
B
D015266:Carcinoma, Merkel Cell / Q000175:diagnosis* / Q000628:therapy / Q000648:ultrastructure; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D011379:Prognosis; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000628:therapy / Q000648:ultrastructure
Carcinomes neuroendocrines cutanés primitifs ou carcinomes à cellules de Merkel. Revue de la littérature.