Variations of peroxides and total antioxidants from the plasma of normal blood donors, as a function of sex, age and blood group.
The level of peroxides and total antioxidants in normal individuals varies with sex, age and the type of blood group. The most significant differences were noticed in peroxide between young and aged subjects (over 60) of both sexes. For the free SH groups, significant differences were found, only in women, in whom it decreased with age. Similar changes were observed in men for the total antioxidants. High peroxide values were observed in donors with blood group 0-I and the lowest levels appeared in subjects with blood groups A and B, in parallel with increased values of total antioxidants. The latter results might be correlated with recent data on favourable prognosis in cancer related to the expression of group A antigens, as well as with the involvement of the glycoproteins in the characterization of blood groups (AB0 system). Our data could also be correlated with the preventive role of antioxidants in the etiology of cancer.
Olinescu
R
R
Radiobiology Department, Fundeni Clinical Hospital, Bucharest, Romania.
Rădăceanu
V
V
Niţă
S
S
Lupeanu
E
E
D000328:Adult; D000375:Aging / Q000097:blood*; D000975:Antioxidants / Q000032:analysis*; D001782:Blood Donors; D001789:Blood Group Antigens; D005260:Female; D006801:Humans; D008054:Lipid Peroxides / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012727:Sex Characteristics; D013438:Sulfhydryl Compounds / Q000097:blood
D000975:Antioxidants; D001789:Blood Group Antigens; D008054:Lipid Peroxides; D013438:Sulfhydryl Compounds