[Interferon as a bronchospastic factor in patients with bronchial asthma].
Twenty three asthmatics were examined during the symptoms free period. Each subject inhaled aerolised human interferon alpha (Hu IFN-alpha, Le) in increasing doses 4000 and 8000 units. IFN inhalation provoked significant decline in FEV1 (by 9.9% after the 1st dose and 6.6% after the 2nd dose on average). This results indicate that inhaled interferon induces bronchospastic reactions in asthmatics.
Krasnowska
M
M
Katedry i Kliniki Chorób Wewnetrznych i Alergologii AM we Wrocławiu.
Małolepszy
J
J
Liebhart
E
E
D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000175:diagnosis / Q000276:immunology*; D001985:Bronchial Provocation Tests; D001986:Bronchial Spasm / Q000276:immunology; D005260:Female; D006801:Humans; D016898:Interferon-alpha / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged
D016898:Interferon-alpha
Interferon jako czynnik spazmogenny oskrzeli u chorych na dychawice oskrzelowa.