Chemiluminescent DNA probes: evaluation and usefulness in forensic cases.
Five phosphatase-labelled oligonucleotide probes were evaluated in respect to their sensitivity, with the help of an optimized chemiluminescent protocol, for DNA-VNTR polymorphism determination. Their usefulness for the identification of biological traces is illustrated with casework examples.
Dimo-Simonin
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N
Institut Universitaire de Médecine Légale, Lausanne, Switzerland.
Brandt-Casadevall
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C
Gujer
H R
HR
D000469:Alkaline Phosphatase / Q000737:chemistry; D001801:Blood Stains; D015139:Blotting, Southern; D001826:Body Fluids / Q000737:chemistry*; D004247:DNA / Q000032:analysis*; D005260:Female; D005554:Forensic Medicine / Q000379:methods*; D006801:Humans; D008163:Luminescent Measurements; D008297:Male; D015345:Oligonucleotide Probes; D011110:Polymorphism, Genetic; D012661:Semen / Q000737:chemistry*; D012680:Sensitivity and Specificity; D014621:Vagina / Q000737:chemistry
D015345:Oligonucleotide Probes; D004247:DNA; D000469:Alkaline Phosphatase