Pregnancy after zygote intra-fallopian transfer using spermatozoa from a patient with Kallmann's syndrome.
A successful zygote intra-Fallopian transfer has been performed using spermatozoa from a patient with Kallmann's syndrome. Spermatogenesis was induced by hormonal treatment but even so, semen quality remained slightly impaired and no pregnancy occurred over 4 years, despite ovulation induction in the patient's spouse. Finally she conceived after assisted procreation by in-vitro fertilization and delivered a healthy baby.
Tournaye
H
H
Centre for Reproductive Medicine, University Hospital, Vrije Universiteit Brussel, Belgium.
Van Steirteghem
A
A
Devroey
P
P
D000328:Adult; D006063:Chorionic Gonadotropin / Q000627:therapeutic use; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000627:therapeutic use; D006801:Humans; D007248:Infertility, Male / Q000188:drug therapy* / Q000209:etiology; D017436:Kallmann Syndrome / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008596:Menotropins / Q000627:therapeutic use; D011247:Pregnancy; D013076:Sperm Count; D013081:Sperm Motility; D013091:Spermatogenesis / Q000187:drug effects; D017388:Zygote Intrafallopian Transfer
D006063:Chorionic Gonadotropin; D007987:Gonadotropin-Releasing Hormone; D008596:Menotropins