title: A case of disseminated Mycobacterium marinum infection in an immunocompetent patient.
abstract: An unusual case of Mycobacterium marinum cutaneous infection is described. As a result of marked delay in the diagnosis, extensive local inflammation and destructive osteomyelitis occurred together with cutaneous dissemination in an immunocompetent host. Pathologic fractures in the infected bone necessitated amputation of the involved digit. The most striking feature of this case was the development of multiple widespread cutaneous lesions for several months following amputation of the infected digit and initiation of appropriate antimicrobial therapy. These new cutaneous lesions may reflect local immune and inflammatory reactions to previously disseminated microorganisms.
authors: Division of Infectious Diseases, Wayne State University School of Medicine, Detroit, Michigan 48201.
authors: J A
authors: JA
authors: Vazquez
authors: J D
authors: JD
authors: Sobel
mesh_terms: D000671:Amputation, Surgical; D004977:Ethambutol / Q000627:therapeutic use; D005260:Female; D005383:Finger Injuries / Q000150:complications*; D050723:Fractures, Bone / Q000209:etiology / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000150:complications / Q000188:drug therapy / Q000382:microbiology; D009170:Nontuberculous Mycobacteria / Q000187:drug effects / Q000302:isolation & purification; D010019:Osteomyelitis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D012293:Rifampin / Q000627:therapeutic use; D017192:Skin Diseases, Bacterial / Q000150:complications / Q000382:microbiology*; D014871:Water Microbiology; D014950:Wounds, Penetrating / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D004977:Ethambutol; D012293:Rifampin