Colony-stimulating factors: a new step in clinical practice. Part I.
Haematopoietic colony stimulating factors (CSFs) stimulate the proliferation, differentiation and functional activity of myelocytes. Since approval of the use of these factors in patients with chemotherapy-induced neutropenia, patients undergoing autologous bone marrow transplantation (BMT) and patients with delayed engraftment after BMT, several other potential clinical uses have been described. Current and potential future clinical applications of CSFs will be reviewed.
Nemunaitis
J
J
Hematopoiesis Programme, Western Pennsylvania Cancer Institute, West Penn Hospital, Pittsburgh 15224.
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy; D016026:Bone Marrow Transplantation; D003115:Colony-Stimulating Factors / Q000627:therapeutic use*; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000627:therapeutic use; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy; D009190:Myelodysplastic Syndromes / Q000188:drug therapy
D003115:Colony-Stimulating Factors; D016178:Granulocyte-Macrophage Colony-Stimulating Factor