title: Mechanism of extension of spinal anaesthesia by extradural injection of local anaesthetic.
abstract: We have examined the effect of extradual injection of 0.5% bupivacaine or normal saline on the progression of spinal anaesthesia in 28 patients undergoing Caesearean section. Three groups were studied. Subarachnoid anaesthesia was established in all patients. Group A (n = 10), the control, received no extradural injection for 20 min. Group B (n = 9) received extradural bupivacaine 10 ml and group C (n = 9) received extradual saline 10 ml 5 min after the subarachnoid injection. Sensory levels were compared at 5-min intervals and extension of the block was found to be similar in groups B and C and significantly faster than the control (P < 0.05). The quality of anaesthesia and incidence of adverse effects was similar for all three groups. We conclude that the mechanism of extension of spinal anaesthesia by extradural injection of local anaesthesia is largely a volume effect.
authors: Department of Anaesthetics, South Cleveland Hospital, Middlesbrough.
authors: C H
authors: CH
authors: Blumgart
authors: D
authors: D
authors: Ryall
authors: B
authors: B
authors: Dennison
authors: L M
authors: LM
authors: Thompson-Hill
mesh_terms: D000328:Adult; D000767:Anesthesia, Epidural / Q000009:adverse effects / Q000379:methods*; D000773:Anesthesia, Obstetrical / Q000009:adverse effects / Q000379:methods*; D000775:Anesthesia, Spinal / Q000009:adverse effects / Q000379:methods*; D002045:Bupivacaine / Q000008:administration & dosage*; D002585:Cesarean Section; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D011247:Pregnancy
chemical_list: D002045:Bupivacaine