title: Efficacy of a drug combination of praziquantel, pyrantel embonate, and febantel against helminth infections in dogs.
abstract: Tablets containing praziquantel, pyrantel embonate, and febantel were tested for efficacy against helminths in dogs. A single treatment with this drug combination gave 100% reductions in Toxocara canis and Taenia hydatigena in experimentally induced infections in dogs. In dogs with naturally acquired infections, treatment gave > 97 to 98% reductions in fecal egg counts attributable to Toxascaris leonina, T canis, and Uncinaria stenocephala. Efficacy against Trichuris vulpis was > 92%.
authors: Department of Clinical Veterinary Medicine, University of Cambridge, England.
authors: S
authors: S
authors: Lloyd
authors: M A
authors: MA
authors: Gemmell
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D004283:Dog Diseases / Q000188:drug therapy* / Q000469:parasitology; D004285:Dogs; D004338:Drug Combinations; D005260:Female; D006146:Guanidines / Q000627:therapeutic use; D006373:Helminthiasis / Q000188:drug therapy; D006374:Helminthiasis, Animal; D008297:Male; D011223:Praziquantel / Q000627:therapeutic use; D011716:Pyrantel Pamoate / Q000627:therapeutic use
chemical_list: D000871:Anthelmintics; D004338:Drug Combinations; D006146:Guanidines; D011223:Praziquantel; D011716:Pyrantel Pamoate; C017309:febantel