Effect of gamma butyrolactone on the hypothalamo-neurohypophyseal system of the gerbil brain after ischemic injury.
The effect of exogenous gamma butyrolactone (GBL) on hypothalamo-neurohypophyseal system of the gerbil brain after ischemic injury was studied by electron microscopy. It was mentioned that GBL hasn't a protective action against ischemically induced injury. We postulate that neurosecretory process is slightly disturbed as a result of irreversible damage of some tissue elements; neurons of supraoptic and paraventricular nuclei, glial cells and axonal endings in neurohypophysis.
Gajkowska
B
B
Laboratory of the Ultrastructure of the Nervous System, Polish Academy of Sciences, Warsaw.
D015107:4-Butyrolactone / Q000494:pharmacology*; D000818:Animals; D005849:Gerbillinae; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects / Q000473:pathology / Q000648:ultrastructure*; D002546:Ischemic Attack, Transient / Q000473:pathology*; D008854:Microscopy, Electron; D010286:Paraventricular Hypothalamic Nucleus / Q000187:drug effects / Q000473:pathology / Q000648:ultrastructure; D010904:Pituitary Gland, Posterior / Q000187:drug effects / Q000473:pathology / Q000648:ultrastructure; D012016:Reference Values; D013495:Supraoptic Nucleus / Q000187:drug effects / Q000473:pathology / Q000648:ultrastructure
D015107:4-Butyrolactone