Preventive intervention in breast cancer, but when?
After an introductory note on primary preventive intervention of breast cancer during adulthood, the author defends and extends a hypothesis that relates most of the known risk factors for this disease to the development of preneoplastic lesions in the breast. If changes in lifestyle concerning nutritional and/or reproductive risk factors during puberty and adolescence would turn out to be unacceptable socially, an alternative approach might be found in chemoprevention based on cell differentiation.
De Waard
F
F
Department of Epidemiology, University of Utrecht, The Netherlands.
D000293:Adolescent; D000328:Adult; D001943:Breast Neoplasms / Q000473:pathology / Q000517:prevention & control*; D005260:Female; D006801:Humans; D009747:Nutritional Physiological Phenomena; D011230:Precancerous Conditions / Q000473:pathology / Q000517:prevention & control