title: Evolution of linear plasmids.
abstract: Linear plasmids are genetic elements commonly found in yeast, filamentous fungi, and higher plants. In contrast to all other plasmids they possess terminal inverted repeats and terminal bound proteins and encode their own DNA and RNA polymerases. Here we present alignments of conserved amino acid sequences of both the DNA and RNA polymerases encoded by those linear plasmids for which DNA sequence data are available. Additionally these sequences are compared to a number of polymerases encoded by related viral and cellular entities. Phylogenetic trees have been established for both types of polymerases. These trees appear to exhibit very similar subgroupings, proving the accuracy of the method employed.
authors: Ruhr-Universität Bochum, Lehrstuhl für Allgemeine Botanik, FRG.
authors: F
authors: F
authors: Kempken
authors: J
authors: J
authors: Hermanns
authors: H D
authors: HD
authors: Osiewacz
mesh_terms: D000595:Amino Acid Sequence; D001435:Bacteriophages / Q000201:enzymology / Q000235:genetics; D005075:Biological Evolution; D002736:Chloroplasts / Q000201:enzymology; D004247:DNA; D004259:DNA-Directed DNA Polymerase / Q000737:chemistry / Q000235:genetics*; D012321:DNA-Directed RNA Polymerases / Q000737:chemistry / Q000235:genetics*; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics; D005658:Fungi / Q000201:enzymology / Q000235:genetics; D008969:Molecular Sequence Data; D010957:Plasmids; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D014780:Viruses / Q000201:enzymology / Q000235:genetics
chemical_list: D004247:DNA; D012321:DNA-Directed RNA Polymerases; D004259:DNA-Directed DNA Polymerase