Kimura's disease and angiolymphoid hyperplasia with eosinophilia: clinical and histopathologic differences.
BACKGROUND
There has been considerable controversy about the relation between Kimura's disease and angiolymphoid hyperplasia with eosinophilia (ALHE).


OBJECTIVE
We describe the clinical and histopathologic differences between the two diseases.


METHODS
We reviewed clinical findings and histopathologic changes in two cases of Kimura's disease and three cases of ALHE.


RESULTS
Kimura's disease shows typical lymphoid follicles. It is associated with lymphadenopathy and is always accompanied by peripheral eosinophilia. ALHE shows typical changes in endothelial cells. It is characterized by superficial papules or nodules with no lymphadenopathy and is less frequently accompanied by peripheral eosinophilia.


CONCLUSIONS
Kimura's disease and ALHE are separate entities.
Chun
S I
SI
Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea.
Ji
H G
HG
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000145:classification / Q000188:drug therapy / Q000473:pathology*; D003452:Cryosurgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D000305:Adrenal Cortex Hormones