[Outcome of pregnancies obtained by fertilization in vitro. Experience at the V. Olivier Ward (department of Professor Monnier, Lille University Hospital Center) and review of the literature].
The outcome of 87 pregnancies obtained by fertilisation in vitro and progressing beyond 20 weeks of amenorrhea monitored in the Victor-Olivier Ward (Prof. Monnier, Lille Teaching Hospital Group) was analysed. Results were compared with those in the literature. The group was characterised by three features: age, the number of primipara and above all the multiple pregnancy rate. One quarter of FIV pregnancies are multiple pregnancies and almost two newborn out of live are the result of multiple pregnancies. Almost 70 per cent of clinical pregnancies progressed beyond six months. Pregnancy pathology was represented by a marked worsening of the prematurity rate and by a slightly increased risk of fetal under-development. The cesarean section rate was very markedly increased. Sex ratio, and perinatal mortality, malformation and chromosomal aberration rates were similar to those for spontaneous pregnancies. Results are reassuring overall, the pathology being encountered in pregnancies of this type being only partially explained by age, the number of primipara and the multiple pregnancy rate. This pathology could possibly be explained by the underlying situation in which sterility occurred.
Tiberghien
B
B
Pavillon V. Olivier, CHU de Lille.
Monnier
J C
JC
Commercon
G
G
Maunoury-Lefevre
C
C
Deshorgues
A C
AC
Buvat
J
J
Buvat-Herbaut
M
M
Savary
B
B
Vinatier
D
D
Bernardi
C
C
D000022:Abortion, Spontaneous / Q000209:etiology; D000328:Adult; D001724:Birth Weight; D002869:Chromosome Aberrations / Q000209:etiology; D025063:Chromosome Disorders; D000013:Congenital Abnormalities / Q000209:etiology; D005260:Female; D005307:Fertilization in Vitro; D005315:Fetal Diseases / Q000209:etiology; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D008297:Male; D007744:Obstetric Labor Complications / Q000209:etiology; D010298:Parity; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology; D011272:Pregnancy, Multiple; D012307:Risk Factors
Evolution des grossesses obtenues par fécondation in vitro. Expérience du Pavillon V. Olivier (service du Pr Monnier, CHU de Lille) et revue de la littérature.