[Proteolytic enzymes of the digestive tract in ethanol poisoning].
The present paper reviews the literature on changes of proteolytic enzymes activity, disorders of protein digestion and absorption of protein degradation products from digestive tract in ethanol intoxication. Magnitude of the change depends on concentration, dose and time of ethanol consumption. Acute ethanol intoxication causes increase in gastric and pancreatic proteolytic enzymes secretion and reduces amino acids and peptides absorption. Chronic ethanol consumption results in reduced synthesis and secretion of gastric and pancreatic proteinases.
Skrzydlewska
E
E
Zakład Analizy Instrumentalnej Akademii Medycznej, Białymstoku.
Worowski
K
K
Roszkowska-Jakimiec
W
W
D000426:Alcohol Dehydrogenase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D000435:Alcoholic Intoxication / Q000201:enzymology* / Q000378:metabolism; D000444:Aldehyde Dehydrogenase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D003864:Depression, Chemical; D004064:Digestive System / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D010450:Endopeptidases / Q000378:metabolism*; D000431:Ethanol / Q000008:administration & dosage* / Q000378:metabolism / Q000633:toxicity; D006023:Glycoproteins / Q000037:antagonists & inhibitors / Q000378:metabolism; D006801:Humans; D011480:Protease Inhibitors
D006023:Glycoproteins; D011480:Protease Inhibitors; D000431:Ethanol; D000426:Alcohol Dehydrogenase; D000444:Aldehyde Dehydrogenase; D010450:Endopeptidases
Enzymy proteolityczne przewodu pokarmowego w zatruciu etanolem.