Sudden death due to lymphoplasmacytic hypophysitis.
We report the case of a 37-year-old mentally retarded woman who died suddenly with premortem clinical signs of diabetes insipidus. At autopsy, her pituitary was infiltrated and destroyed by a lymphoplasmacytic infiltrate, affecting the posterior pituitary more severely than the anterior pituitary. Vitreous electrolytes showed a pattern of hypertonic dehydration, compatible with diabetes insipidus.
Blisard
K S
KS
Department of Pathology and Laboratory Medicine, University of Cincinnati Medical Center, OH 45267-0529.
Pfalzgraf
R R
RR
Balko
M G
MG
D000328:Adult; D003645:Death, Sudden / Q000209:etiology*; D003919:Diabetes Insipidus / Q000150:complications*; D005260:Female; D006801:Humans; D010900:Pituitary Diseases / Q000150:complications / Q000473:pathology; D010903:Pituitary Gland, Anterior / Q000473:pathology*