What does rCBF-SPECT offer in schizophrenia?
Schizophrenia is a major psychiatric problem common in the younger population. Structural imaging and findings on autopsy have not yet revealed a specific deficit in these patients. Uncertainty in clinical diagnosis based on a set of signs and symptoms is another drawback in the management of this patient population. Regional cerebral blood flow studies (rCBF) using single photon emission computed tomography (SPECT) offers the opportunity to study the underlying phenomenon and to detect the specific functional deficits in schizophrenia.
Syed
G M
GM
Department of Nuclear Medicine, King's College Hospital, Denmark Hill, London, UK.
Barrett
J J
JJ
Toone
B K
BK
D000662:Amphetamines; D001921:Brain / Q000098:blood supply* / Q000000981:diagnostic imaging; D002560:Cerebrovascular Circulation / Q000502:physiology*; D006801:Humans; D007457:Iodine Radioisotopes; D020367:Iofetamine; D015609:Organotechnetium Compounds; D010091:Oximes; D012559:Schizophrenia / Q000000981:diagnostic imaging*; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon; D014980:Xenon Radioisotopes
D000662:Amphetamines; D007457:Iodine Radioisotopes; D015609:Organotechnetium Compounds; D010091:Oximes; D014980:Xenon Radioisotopes; D019690:Technetium Tc 99m Exametazime; D020367:Iofetamine