title: [Antiperinuclear antibodies and corrisponding antigens].
abstract: Antiperinuclear factors (APF) are directed to epithelial cell "kerato-hyaline granules". Standardization of the APF test has been achieved, but the way to express the results is still debatable. APF were found to be present in 76% of rheumatoid arthritis (RA) patients: thus the sensitivity and the specificity for RA were 76 and 97%, respectively. No clinical or serological associations were substantiated in RA. The antigens targetted by these auto-antibodies are extremely variable from one to another donor.
authors: Laboratoire d'Immunologie, CHU, Brest.
authors: P
authors: P
authors: Youinou
authors: J M
authors: JM
authors: Berthelot
authors: A
authors: A
authors: Péron
authors: A M
authors: AM
authors: Leroux
authors: P
authors: P
authors: Le Goff
mesh_terms: D000974:Antibodies, Antinuclear / Q000032:analysis* / Q000302:isolation & purification; D000940:Antigenic Variation; D001172:Arthritis, Rheumatoid / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D006801:Humans
chemical_list: D000974:Antibodies, Antinuclear; C030902:antiperinuclear factor
vernacular_title: Anticorps anti-périnucléaires et antigènes correspondants.