title: Engineering design of vascular prostheses.
abstract: The replacement and bypass of arteries of diameter greater than 6 mm with textile vascular prostheses has proved very successful since they were first introduced forty years ago. Although manufacturers continue to improve their products and make them of consistent quality for increased safety and performance and to facilitate their use by surgeons, most of the research work in this area is concerned with the development of small-diameter prostheses. Current expanded PTFE and textile prostheses do not perform satisfactorily when their diameters are reduced to less than 6 mm. For the small-diameter prostheses it will be necessary to develop less thrombogenic materials and to design the structure of the prostheses more closely to match the mechanical properties of the natural arteries. The purpose of this paper is to discuss the design requirements and to review the development of large- and small-diameter vascular prostheses.
authors: Department of Clinical Engineering, University of Liverpool.
authors: T V
authors: TV
authors: How
authors: R
authors: R
authors: Guidoin
authors: S K
authors: SK
authors: Young
mesh_terms: D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D001698:Biomedical Engineering; D001807:Blood Vessel Prosthesis; D011474:Prosthesis Design
chemical_list: D001672:Biocompatible Materials