title: Neutrophilic intracellular acidosis induced by conventional, lactate-containing peritoneal dialysis solutions.
abstract: Exposure of human neutrophils to a conventional, acidic, lactate-containing peritoneal dialysis solution (PDS) resulted in the development of a prompt and substantial intracellular acidosis. It is possible that this intracellular acidosis contributes to cellular dysfunction.
authors: Department of Medicine, School of Medicine, University of California, Irvine.
authors: A W
authors: AW
authors: Yu
authors: X J
authors: XJ
authors: Zhou
authors: F Q
authors: FQ
authors: Zhou
authors: Z M
authors: ZM
authors: Nawab
authors: V C
authors: VC
authors: Gandhi
authors: T S
authors: TS
authors: Ing
authors: N D
authors: ND
authors: Vaziri
mesh_terms: D000328:Adult; D002499:Centrifugation, Density Gradient; D015314:Dialysis Solutions / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007773:Lactates / Q000009:adverse effects*; D019344:Lactic Acid; D008297:Male; D009504:Neutrophils / Q000187:drug effects* / Q000378:metabolism; D010530:Peritoneal Dialysis
chemical_list: D015314:Dialysis Solutions; D007773:Lactates; D019344:Lactic Acid