Deletion (7)(p11p15) in a patient with Philadelphia-positive chronic myelogenous leukemia.
We report a case of chronic myelogenous leukemia (CML) with a Philadelphia (Ph) chromosome. During the transformation phase of the disease, a del(7)(p11p15) and a +Ph were identified as additional chromosomal anomalies. We believe that loss of the segment 7p11-->p15 may play an important role in the progression of the disease.
Carrasco Juan
J L
JL
Cytogenetics Service, Faculty of Medicine, University of La Laguna, Tenerife, Canary Islands, Spain.
Otero Gómez
A
A
García Miranda
J L
JL
Trujillo González
M
M
Herrera Fernández
M
M
Bello Hernández
T
T
D001752:Blast Crisis; D002871:Chromosome Banding; D002872:Chromosome Deletion; D002897:Chromosomes, Human, Pair 7; D005260:Female; D006801:Humans; D007621:Karyotyping; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000235:genetics* / Q000473:pathology; D008875:Middle Aged