[The efficacy of a 4-year course of drug treatment for patients with juvenile hypertension].
To evaluate the hypotensive efficacy and effects of some hypotensive drugs on the hemodynamics and concentration of testosterone in its blood plasma the authors examined 205 patients with juvenile hypertension (JH): main group--134 patients; comparison group--71 patients). Course treatment (1.5-2 months) with obsidan, niphedipin, verapamyl was carried out with nondrug treatment during intervals. The obtained data evidence efficacy of the hypotensive treatment. Most patients with JH showed a characteristic increase of the blood testosterone level. After a four-year treatment the testosterone level was within normal levels.
Chernoguz
L S
LS
Zanozdra
N S
NS
Kupchinskaia
E G
EG
D000293:Adolescent; D000328:Adult; D004341:Drug Evaluation; D004351:Drug Resistance; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D009543:Nifedipine / Q000627:therapeutic use*; D011433:Propranolol / Q000627:therapeutic use*; D013739:Testosterone / Q000097:blood; D013997:Time Factors; D014700:Verapamil / Q000627:therapeutic use*
D013739:Testosterone; D011433:Propranolol; D014700:Verapamil; D009543:Nifedipine
Effektivnost' chetyrekhletnogo kursovogo medikamentoznogo lecheniia bol'nykh s iunosheskoĭ gipertenzieĭ.