title: Anisotropy of ultrasonic velocity and elastic properties in normal human myocardium.
abstract: Measurements of ultrasonic quasilongitudinal velocity were made in the muscle fiber plane of excised human myocardium. Multiple adjacent planes across the left ventricular wall were interrogated to assess the transmural dependence of velocity. For each measurement plane, data were obtained in 2-deg increments through the full 360 deg relative to the myofibers. An approximate 1.3% magnitude of anisotropy was observed with maximum velocity along the muscle fibers and minimum velocity perpendicular to the muscle fibers. The known transmural shift in myofiber orientation was evidenced in the anisotropy of velocity as angular shifts between plots obtained from adjacent transmural planes within the same specimen. Measured values of velocity and density were used to estimate the effective C33 and C11 elastic constants of a thin layer of normal myocardium.
authors: Washington University Department of Physics, St. Louis, Missouri 63130.
authors: E D
authors: ED
authors: Verdonk
authors: S A
authors: SA
authors: Wickline
authors: J G
authors: JG
authors: Miller
mesh_terms: D016880:Anisotropy; D004452:Echocardiography; D004548:Elasticity; D006321:Heart / Q000033:anatomy & histology* / Q000502:physiology; D006352:Heart Ventricles / Q000033:anatomy & histology; D006801:Humans; D008954:Models, Biological; D014463:Ultrasonography; D016276:Ventricular Function