Long-term management of basal cell nevus syndrome with topical tretinoin and 5-fluorouracil.
The case of a child with basal cell nevus syndrome whose condition was successfully managed for 10 years with a combination of topical 5-fluorouracil and tretinoin is reported. The concurrent use of these two agents prevented the development of new tumors, inhibited the growth of existing tumors, and caused the regression of superficially invasive basal cell carcinomas.
Strange
P R
PR
Department of Dermatology, Lovelace Medical Center, Albuquerque, New Mexico.
Lang
P G
PG
D001478:Basal Cell Nevus Syndrome / Q000188:drug therapy*; D002675:Child, Preschool; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D012878:Skin Neoplasms / Q000188:drug therapy*; D013997:Time Factors; D014212:Tretinoin / Q000008:administration & dosage / Q000627:therapeutic use*
D014212:Tretinoin; D005472:Fluorouracil