[Is aspartic acid regulator of hemopoiesis?].
The effect of aspartic acid on myelopoiesis was examined. A method of bone marrow cultivation was used in diffusion chambers in vivo. We found that injection of 1 x 10(-4) g/kg aspartic acid to intact rats during 5 days resulted in increase of cloning efficiency of granulocyte-progenitor cells by 24 per cent and growth of cluster/colony-forming unit fibroblastic. On the basis of these data we came to the conclusion that aspartic acid acts directly on hemopoietic cells and stromal system.
Bazarnyĭ
V V
VV
Osipenko
A V
AV
D000818:Animals; D001224:Aspartic Acid / Q000494:pharmacology / Q000502:physiology*; D001853:Bone Marrow / Q000187:drug effects / Q000502:physiology; D001854:Bone Marrow Cells; D003114:Colony-Forming Units Assay; D046508:Culture Techniques; D006410:Hematopoiesis; D008297:Male; D051381:Rats; D017208:Rats, Wistar
D001224:Aspartic Acid
Asparginovaia kislota--reguliator gemopoéza?