Secondary flow in the human common carotid artery imaged by MR angiography.
The blood flow in arteries affects both the biology of the vessels and the development of atherosclerosis. The flow is three-dimensional, unsteady, and difficult to measure or to model computationally. We have used phase-shift-based magnetic resonance angiography to image and measure the flow in the common carotid arteries of a healthy human subject. There was curvature of the vessels and thin-slice dynamic flow imaging showed evidence of the presence of secondary motions. Flexing the cervical spine straightened the vessels and reduced the asymmetry of the flow.
Caro
C G
CG
Centre for Biological and Medical Systems, Imperial College of Science, Technology, and Medicine, London, U.K.
Dumoulin
C L
CL
Graham
J M
JM
Parker
K H
KH
Souza
S P
SP
D000328:Adult; D000792:Angiography / Q000379:methods*; D001783:Blood Flow Velocity; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000502:physiology*; D002574:Cervical Vertebrae / Q000502:physiology; D003198:Computer Simulation; D005069:Evaluation Studies as Topic; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008955:Models, Cardiovascular; D011187:Posture; D012212:Rheology