title: [Chromosome aberrations in chronic myeloid leukemia].
abstract: Chromosome Philadelphia is a cytogenetic marker of chronic myeloid leukemia. It results from a translocation t(9;22) or other, more complex, translocations. Before the onset of blastic crisis, secondary aberrations occur, the most often--trisomy 8, isochromosome 17q and extra Ph chromosome. Their presence has a prognostic significance. Particular aberrations may occur in association with determined haematological and clinical features.
authors: Katedry i Zakładu Patofizjologii AM, Wrocławiu.
authors: O
authors: O
authors: Haus
mesh_terms: D001752:Blast Crisis / Q000209:etiology / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007621:Karyotyping; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000209:etiology / Q000235:genetics* / Q000473:pathology; D010677:Philadelphia Chromosome; D014178:Translocation, Genetic / Q000235:genetics*; D014314:Trisomy
vernacular_title: Aberracje chromosomów w przewlekłej białaczce szpikowej.