[Immobilization of phospholipid micelles on modified apoHDL-Sepharose].
There was developed a procedure for immobilization of phosphatidyl cholines (Egg yolk phosphatidyl choline and polyunsaturated soya beams phosphatidyl choline) on the modified apoHDL-Sepharose. The formation of phospholipid micelles was proved by linear dependence of the content of the sorbed phosphatidyl choline versus, the content of apoHDL bound to Sepharose. Incubation of apoHDL/PC-Sepharose with human plasma was shown to change the plasma lipid composition. The apoHDL/PC-Sepharose might be used for correction of the plasma lipid composition on vitro experiments.
Antonov
I V
IV
Zamaeva
N Iu
NIu
Medvedeva
N V
NV
Misharin
A Iu
AIu
D001053:Apolipoproteins / Q000737:chemistry*; D006801:Humans; D008055:Lipids / Q000097:blood; D008075:Lipoproteins, HDL / Q000737:chemistry*; D008823:Micelles; D010713:Phosphatidylcholines; D012685:Sepharose / Q000031:analogs & derivatives* / Q000737:chemistry
D001053:Apolipoproteins; D008055:Lipids; D008075:Lipoproteins, HDL; D008823:Micelles; D010713:Phosphatidylcholines; C078752:apoHDL-sepharose; D012685:Sepharose
Immobilizatsiia fosfolipidnykh mitsell na modifitsirovannoĭ apoLVP- Sefarose.