[Fluoxetine and depression in the elderly. Clinical experience].
Eighty-six patients aged between 60 and 80 years and affected with major depression according to the diagnostic criteria of the DSM III-R were treated with fluoxetine per os at the single dosage of 20 mg/die. At prearranged intervals psychometric reagents were administered for the evaluation of any variations in the depressive symptomatology. Already at the 1st examination after 14 days' treatment a considerable improvement in the psychopathological picture was observed. This improvement remained constant at the subsequent examinations and the follow-up after 90 days. The tolerability was excellent and the side effect mild, with a tendency to regress after the first days of therapy. The clinical assessment and the psychometric findings both suggest that fluoxetine has a useful action on major depression in the elderly.
Ambrosio
L A
LA
Servizio di Psichaitria, Ospedale Civile dell'Annuziata, Cosenza.
Barrese
E
E
Bertini
M
M
Buccomino
D
D
Casini
A
A
Filippo
A
A
Filippo
P
P
Marchese
G
G
Paoletti
C
C
D000368:Aged; D000369:Aged, 80 and over; D003863:Depression / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D005473:Fluoxetine / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales
D005473:Fluoxetine
Fluoxetina e depressione nell'anziano. Esperienze cliniche.