Maternal psychotropic medication and neonatal behavior.
A sample of 29 psychiatrically ill women and a non-ill comparison group were recruited during pregnancy. Twelve of the ill mothers were receiving antipsychotic and anti-anxiety medication during the final trimester of pregnancy. The behavior of their infants was assessed at 3 and 14 days of age using the Brazelton Neonatal Behavioral Assessment Scale. Compared to infants of non-ill mothers and infants of ill nonmedicated mothers, infants whose mothers received antipsychotic drugs--particularly those in the phenothiazine family--showed a stable pattern of poor neonatal motor functioning that included tremulousness, hypertonicity, and poor motor maturity. It was speculated that this behavior was symptomatic of a neonatal abstinence or withdrawal syndrome.
Auerbach
J G
JG
Department of Psychology, Hebrew University of Jerusalem.
Hans
S L
SL
Marcus
J
J
Maeir
S
S
D002648:Child; D002652:Child Behavior / Q000187:drug effects*; D005260:Female; D006801:Humans; D007231:Infant, Newborn / Q000523:psychology*; D008137:Longitudinal Studies; D008297:Male; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011619:Psychotropic Drugs / Q000009:adverse effects*; D016037:Single-Blind Method; D012907:Smoking / Q000009:adverse effects; D013375:Substance Withdrawal Syndrome / Q000209:etiology*
D011619:Psychotropic Drugs