Comparison between two different assays for measurements of allergen-specific IgE and skin prick test in the diagnosis of insect venom allergy.
Forty-one patients stung by wasp and 29 by bee were evaluated by comparing the correlation between skin prick test (SPT), Phadebas radioallergosorbent test (P-RAST) and Magic Lite SQ Specific IgE assay (LIA). All patients had had a systemic reaction to insect sting. In the patients stung by bee we found agreement between SPT and P-RAST, and SPT and LIA. Similarly, there were no significant differences in sensitivity between P-RAST and LIA (p > 0.05). In patients stung by wasp, SPT was found to be more sensitive than P-RAST. There were no differences between SPT and LIA or between P-RAST and LIA.
Eiken
P
P
Dept of Allergy, State University Hospital, Copenhagen, Denmark.
Mosbech
H
H
Jacobsen
L
L
Larsen
P
P
Scharling
B
B
Svendsen
U G
UG
Søes-Petersen
U
U
D000485:Allergens / Q000032:analysis*; D001514:Bee Venoms / Q000276:immunology*; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis* / Q000276:immunology; D007118:Immunoassay / Q000379:methods*; D007073:Immunoglobulin E / Q000032:analysis*; D007299:Insect Bites and Stings / Q000276:immunology*; D008163:Luminescent Measurements; D011852:Radioallergosorbent Test; D012680:Sensitivity and Specificity; D012882:Skin Tests; D014862:Wasp Venoms / Q000276:immunology*
D000485:Allergens; D001514:Bee Venoms; D014862:Wasp Venoms; D007073:Immunoglobulin E