[Comparative evaluation of the wound-healing effect of benzofuracaine, etaden, and xanthinol nicotinate in an experiment].
The effect of benzofuracaine, etaden, and xanthinol nicotinate on the healing of skin wounds was studied in rat experiments. On days 1-14 of postmechanical injury, intramuscular benzofuracaine (15, 30, 60, and 120 mg/kg), etaden (20 mg/kg), and xanthinol nicotinate (each drug alone) reparative processes in the skin wounds developed more rapidly and processes of microcirculation in the region of the injury were normalized. The wound-healing effect of benzofurocaine in an ortimal dose of 60 mg/kg was more marked than that op etaden and xanthinol nicotinate. With benzofuracaine and etaden, the skin wounds healed completely by the 14th day of the experiment in 57% and 28.6% of animals, respectively. Such cases were not encountered among animals treated with xanthinol nicotinate and in the controls (untreated animals).
Stepaniuk
G I
GI
Ornostaĭ
V V
VV
Kozlov
V G
VG
D000225:Adenine / Q000031:analogs & derivatives* / Q000494:pharmacology; D000779:Anesthetics, Local / Q000494:pharmacology*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D001572:Benzofurans; D005260:Female; D008297:Male; D051381:Rats; D014945:Wound Healing / Q000187:drug effects*; D014971:Xanthinol Niacinate / Q000494:pharmacology*
D000779:Anesthetics, Local; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001572:Benzofurans; C014531:etaden; D014971:Xanthinol Niacinate; C040205:benzofurocaine; D000225:Adenine
Sravnitel'naia otsenka ranozazhivliaiushchego deĭstviia benzofurokaina, étadena i ksantinola nikotinata v éksperimente.