[Study of the dynamics of human serum albumin by coherent Rayleigh dispersion of Mossbauer radiation].
The measurements of angle dependencies of total and elastic Rayleigh scattering of Mossbauer radiation intensities have been performed for human serum albumin (HSA) with hydration degrees h = 0.13 and h = 0.4. The extended model was developed for calculating the inelastic intensity of Rayleigh scattering. Original data for HSA and published data on met-Mb were fitted within the frame of this model. The best agreement with experiment was obtained when two types of intraglobular motions were taken into account: individual motions of small side-chain groups and cooperative (mechanical) motions of segments (most probable alpha-helices). Long-range correlated motions are essential at low hydration degree. The possibilities of application of the coherent version of RSMS technique are described.
Krupianskiĭ
Iu F
IuF
Albaneze
D
D
Gol'danskiĭ
V I
VI
Gorbunova
Iu V
IuV
Deriu
A
A
Zhuravleva
T V
TV
Kavatorta
F
F
Kurinov
I V
IV
Suzdalev
I P
IP
D006801:Humans; D008786:Metmyoglobin / Q000737:chemistry; D008962:Models, Theoretical; D012542:Scattering, Radiation; D012709:Serum Albumin / Q000737:chemistry*; D015204:Spectroscopy, Mossbauer
D012709:Serum Albumin; D008786:Metmyoglobin
Izuchenie dinamiki syvorotochnogo al'bumina cheloveka metodom kogerentnogo réleevskogo rasseianiia Messbauérovskogo izlucheniia.