The histologic diagnosis of Hodgkin's disease.
Histologic criteria for the diagnosis of Hodgkin's disease are being modified, primarily as a result of phenotypic analysis. It seems likely that non-Hodgkin's lymphomas have been diagnosed as mixed-cellularity and lymphocytic-depletion Hodgkin's disease on the basis of previously accepted histologic criteria. As a result, phenotypic studies are indicated in all examples of lymphocytic-depletion Hodgkin's disease and in those cases of mixed-cellularity Hodgkin's disease in which the histologic findings are unusual. The effects of genotypic analysis on histologic criteria remain to be elucidated.
Butler
J J
JJ
Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
D003937:Diagnosis, Differential; D006689:Hodgkin Disease / Q000473:pathology*; D006801:Humans; D007244:Infectious Mononucleosis / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology