Influence of ceftriaxone on emergence of Clostridium difficile.
The influence of long-term ceftriaxone administration on the emergence of Clostridium difficile was studied with 80 patients receiving ceftriaxone for 14 days. In five patients (6.3%) C. difficile was cultured. The appearance of gastrointestinal disturbances during treatment with ceftriaxone was common, but the rate of emergence of C. difficile in immunocompetent patients was not high.
Lejko-Zupanc
T
T
Department of Infectious Diseases, University Medical Center Ljubljana, Japljeva.
Zakelj
J
J
Strle
F
F
Janc
M
M
Pleterski-Rigler
D
D
D000293:Adolescent; D000328:Adult; D000368:Aged; D002443:Ceftriaxone / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D016360:Clostridioides difficile / Q000187:drug effects* / Q000302:isolation & purification; D003967:Diarrhea / Q000382:microbiology; D004352:Drug Resistance, Microbial; D004761:Enterocolitis, Pseudomembranous / Q000382:microbiology; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged
D002443:Ceftriaxone