title: A model for evaluating the cost-effectiveness of cholesterol-lowering treatment.
abstract: We describe and illustrate the use of a generalizable model for evaluating the cost-effectiveness of alternative cholesterol-lowering treatments. We combine standard incidence-based techniques for measuring the cost of illness with logistic risk functions from the Framingham Heart Study to project, for persons with known coronary risk characteristics, the likelihood of developing coronary heart disease (CHD) over a lifetime as well as a number of related outcomes, including the expected loss of years of life due to CHD, the expected lifetime direct and indirect costs of CHD, and the changes in these outcomes that would result from cholesterol-lowering treatment.
authors: University of Pennsylvania.
authors: H
authors: H
authors: Glick
authors: J F
authors: JF
authors: Heyse
authors: D
authors: D
authors: Thompson
authors: R S
authors: RS
authors: Epstein
authors: M E
authors: ME
authors: Smith
authors: G
authors: G
authors: Oster
mesh_terms: D000328:Adult; D000368:Aged; D000924:Anticholesteremic Agents / Q000191:economics*; D003198:Computer Simulation; D003362:Cost-Benefit Analysis; D006801:Humans; D006937:Hypercholesterolemia / Q000517:prevention & control*; D008017:Life Expectancy; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
chemical_list: D000924:Anticholesteremic Agents