Renal and hepatic output of glutathione in plasma and whole blood.
Measurement of glutathione (GSH) output by the rat kidney and liver demonstrated a substantial net release into red cells across both tissues. The results suggest important roles for kidney and liver in the maintenance of GSH concentrations in red cells and a significant role for the red cell in the interorgan transport of GSH.
Dass
P D
PD
Department of Pathology, Loyola University Medical Center, Maywood, IL 60153.
Bermes
E W
EW
Holmes
E W
EW
D000595:Amino Acid Sequence; D000818:Animals; D001692:Biological Transport; D004912:Erythrocytes / Q000378:metabolism; D005978:Glutathione / Q000097:blood*; D007668:Kidney / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008297:Male; D008954:Models, Biological; D008969:Molecular Sequence Data; D051381:Rats; D017207:Rats, Sprague-Dawley
D005978:Glutathione