[Mutagenic activity of the azo dye Disperse Orange 2K and its basic component Reax dispenser].
Mutagenic activity of inhaled dispersed orange 2K nitrodye (DON 2K) and Reax' disperser was evaluated. Chronically inhaled DON 2K (with disperser) in concentration 28.6 mg/m3 is a genetic danger for an individual and population, being also a selective by injurious++ to the red blood cells. Chronically inhaled Reax' disperser (25.7 and 5.8 mg/m3) shows low mutagenic activity in somatic tissue. Thus, the mutagenic effect of DON 2K with disperser (composition is constant) is explained by nitrodye and not a disperser.
Khipko
S E
SE
Paranich
L I
LI
Zvezdaĭ
V I
VI
Starchenko
G D
GD
Vashchuk
N A
NA
D000280:Administration, Inhalation; D000818:Animals; D001391:Azo Compounds / Q000008:administration & dosage / Q000633:toxicity*; D001853:Bone Marrow / Q000648:ultrastructure*; D002869:Chromosome Aberrations / Q000235:genetics*; D004396:Coloring Agents / Q000008:administration & dosage / Q000633:toxicity*; D008031:Lignin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000633:toxicity; D008297:Male; D008957:Models, Genetic; D009153:Mutagens / Q000008:administration & dosage / Q000633:toxicity*; D009154:Mutation / Q000187:drug effects* / Q000235:genetics; D051381:Rats; D013094:Spermatozoa / Q000648:ultrastructure*
D001391:Azo Compounds; D004396:Coloring Agents; D009153:Mutagens; C001545:lignosulfuric acid; D008031:Lignin
Mutagennaia aktivnost' azokrasitelia dispersnogo oranzhevogo 2K i ego osnovnogo komponenta dispergatora reaksa.