title: [Efficacy and tolerance of a dietary iron supplement (Bio-fer) in pregnancy anemia].
abstract: Fifty pregnant women with a hemoglobin between > 10 and < or = 12 g/100 ml during the second three months of pregnancy participated in a non-comparative clinical trial intended to evaluate, during a one month treatment period, the acceptability and effectiveness of an iron supplement (Bio-fer), combined with a high iron diet. Gastric discomfort regressed (present in 11 and 3 women before and after treatment) (p < 0.05), the same applying to constipation (p < 0.05) (present in 17 and 8 women before and after treatment). Reasons for abandoning treatment were nausea (n = 2) and vertigo (n = 1). Anemia or deficiency, evaluated on the basis of hemoglobin and iron-binding capacity levels, improved or stabilised in 34 patients out of 47 (72.3%). Hemoglobin increased (p < 0.0001) on average from 11.4 +/- 0.6 to 11.7 +/- 0.8 g/100 ml.
authors: Laboratoire de biologie du Point Médical, Dijon.
authors: J P
authors: JP
authors: Loiseau
authors: B
authors: B
authors: Lequeu
authors: P
authors: P
authors: Brunet Lecomte
authors: M
authors: M
authors: Fontaine
mesh_terms: D000328:Adult; D000747:Anemia, Hypochromic / Q000097:blood / Q000178:diet therapy / Q000188:drug therapy*; D005260:Female; D006452:Hemoglobinometry; D006801:Humans; D007501:Iron / Q000008:administration & dosage / Q000627:therapeutic use*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood / Q000188:drug therapy*; D013997:Time Factors
chemical_list: D007501:Iron
vernacular_title: Efficacité et tolérance d'un complément au fer alimentaire (Bio-fer) dans l'anémie gravidique.