title: CD11B lymphocytes in type 1 diabetes mellitus of recent onset.
abstract: To evaluate the behaviour of CD8+ cells (suppressor/cytotoxic T lymphocytes) and CD8+Leu15+ cells (CD11B, suppressor T lymphocytes) in type 1 diabetes mellitus, 27 newly diagnosed diabetic patients and 47 normal controls were studied. CD8 cells were significantly increased in 6 patients, decreased in 9 and unchanged in 12. In all diabetic patients was present a lack of CD8+ Leu15+ cells. These results show that in newly diagnosed type 1 diabetes mellitus, suppressor T lymphocytes are reduced independently from the number of CD8 cells.
authors: Cattedra di Patologia Speciale Medica e Metodologia Clinica 3, Naples, Italy.
authors: A
authors: A
authors: Bizzarro
authors: A
authors: A
authors: De Bellis
authors: V
authors: V
authors: Amoresano Paglionico
authors: M
authors: M
authors: Auletta
authors: A
authors: A
authors: Gattoni
authors: P
authors: P
authors: Altucci
authors: G
authors: G
authors: Iacono
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology*; D006801:Humans; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*; D013997:Time Factors