Trypsin inhibitor and maternal reunion increase plasma cholecystokinin in neonatal rats.
Intragastric soybean trypsin inhibitor increased plasma CCK bioactivity by 87% in nondeprived, 9-12-day-old rat pups. Reunion with the dam for 1 h after overnight maternal deprivation also increased plasma CCK significantly. These results demonstrate that CCK can be released from the small intestine of rats as early as postnatal day 9.
Weller
A
A
Department of Psychology, Bar Ilan University, Ramat Gan, Israel.
Corp
E S
ES
Tyrka
A
A
Ritter
R C
RC
Brenner
L
L
Gibbs
J
J
Smith
G P
GP
D000818:Animals; D000831:Animals, Newborn; D002766:Cholecystokinin / Q000097:blood*; D005260:Female; D008425:Maternal Behavior; D008426:Maternal Deprivation; D011247:Pregnancy; D051381:Rats; D017207:Rats, Sprague-Dawley; D014361:Trypsin Inhibitors / Q000494:pharmacology*
D014361:Trypsin Inhibitors; D002766:Cholecystokinin