The HIT protein family: a new family of proteins present in prokaryotes, yeast and mammals.
By comparing the sequence of a putative translation product from a Saccharomyces cerevisiae split gene with several data-bases, I have uncovered a new protein family. Members of this family are found in prokaryotes as well as in lower and higher eukaryotes. The function of these proteins is unknown but they share a characteristic histidine triad that may be involved in zinc binding. This group of protein has been named the HIT protein family.
Séraphin
B
B
EMBL, Heidelberg, Germany.
D000595:Amino Acid Sequence; D000818:Animals; D016949:Azospirillum / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics; D002417:Cattle; D000458:Cyanobacteria / Q000235:genetics; D005656:Fungal Proteins / Q000235:genetics; D008969:Molecular Sequence Data; D009174:Mycoplasma / Q000235:genetics; D011506:Proteins / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D013045:Species Specificity
D001426:Bacterial Proteins; D005656:Fungal Proteins; D011506:Proteins