title: Noninflammatory bullae associated with epsilon-aminocaproic acid infusion.
abstract: Three patients who had cardiac surgery developed a transient, noninflammatory subepidermal bullous eruption on the legs after epsilon-aminocaproic acid infusion. Fibrin thrombi were demonstrated in papillary dermal vessels. The use of epsilon-aminocaproic acid as an antifibrinolytic agent may predispose patients to cutaneous vascular thromboses.
authors: Department of Dermatology, University of Alabama, Birmingham.
authors: C P
authors: CP
authors: Brooke
authors: E M
authors: EM
authors: Spiers
authors: E F
authors: EF
authors: Omura
mesh_terms: D000328:Adult; D000368:Aged; D015119:Aminocaproic Acid / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D007868:Leg Dermatoses / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000473:pathology
chemical_list: D015119:Aminocaproic Acid