Influence of different methods of vagotomies on the secretion of cholecystokinin in dogs.
In six dogs, a selective proximal vagotomy, gastric vagotomy, and truncal vagotomy were performed successively. Basal and postprandial cholecystokinin (CCK) concentrations in the peripheral blood were measured by radioimmunoassay. After all the different types of vagotomy, especially after truncal vagotomy, an increased postprandial secretion of CCK was found compared with the healthy animal. Possible causes discussed are the cutting of vagal fibers, which might inhibit the secretion of CCK cells, and the changed gastric and pancreatic secretion.
König
F
F
Department of General Surgery, University of Göttingen, Federal Republic of Germany.
Köhler
H
H
Nustede
R
R
Bartkowski
R
R
Schafmayer
A
A
D000818:Animals; D002766:Cholecystokinin / Q000097:blood / Q000378:metabolism*; D004285:Dogs; D004435:Eating; D011863:Radioimmunoassay; D014629:Vagotomy, Proximal Gastric; D015167:Vagotomy, Truncal
D002766:Cholecystokinin