[Effective and ineffective erythropoiesis in long-term hemorrhages].
The investigation of effective and ineffective erythropoiesis in long-term hemorrhages has shown that the index of normal erythroblasts maturation is decreased down to 0.7 +/- 0.01 (P < 0.01) that evidences disorders in the process of proliferation and differentiation of the erythron cells. A rise of ineffective erythropoiesis was observed at the level of polychromatophilic normal erythroblasts , the mean number of PAS (positive cells) comprised 22.9 +/- 4.1% (P < 0.05). Erythropoiesis intensity was lowered and erythrocyte life was shortened. The data obtained are important for the evaluation of the erythron system lesion and purposeful therapy.
Khamzaliev
B Kh
BKh
Dzhalalova
V A
VA
Adilov
M A
MA
D000328:Adult; D001853:Bone Marrow / Q000473:pathology*; D002455:Cell Division / Q000502:physiology; D003093:Colitis, Ulcerative / Q000097:blood* / Q000150:complications; D004905:Erythrocyte Aging / Q000502:physiology; D004906:Erythrocyte Count; D004912:Erythrocytes / Q000473:pathology*; D015672:Erythroid Precursor Cells / Q000473:pathology*; D004920:Erythropoiesis / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008551:Melena / Q000097:blood* / Q000209:etiology; D008875:Middle Aged; D010438:Peptic Ulcer Hemorrhage / Q000097:blood*; D013997:Time Factors
Effektivnyĭ i neéffektivnyĭ éritropoez pri dlitel'nykh gemorragiiakh.