Mapping the putative RNA helicase genes by sequence overlapping.
An 'electronic' gene mapping procedure based on computer-aided search for overlapping gene sequences was used to identify adjacent genes and localize several putative RNA helicase genes to different chromosomes. PRP28 and AMD1 genes map to the right arm of chromosome IV next to sup2, which encodes a tyrosine tRNA. PRP16, previously mapped to chromosome XI, is tightly linked to MRP-L20. PRP22 is adjacent to PRE1, whose chromosomal location is currently unknown. The utility of this approach in yeast gene mapping is evaluated.
Chang
T H
TH
Department of Molecular Genetics, Ohio State University, Columbus 43210.
Baum
B
B
D002874:Chromosome Mapping / Q000379:methods*; D015825:Chromosomes, Fungal; D020365:RNA Helicases; D012316:RNA Nucleotidyltransferases / Q000235:genetics*; D012441:Saccharomyces cerevisiae / Q000235:genetics*
D012316:RNA Nucleotidyltransferases; D020365:RNA Helicases