[Tuberous sclerosis: broadening of the diagnosis using MR tomography and computed tomography].
Ten children and a 22-y old women with tuberous sclerosis were studied. All children were epileptic but only 8 had skin lesions (white spots, sebaceous adenoma), 4 had rhabdomyoma of the heart and 4 children had astrocytoma of the retina; only in 4 children was the entire triad of tuberous sclerosis seen. The young woman with a hemorrhage of an angiolipoma of the kidney had no other symptoms of tuberous sclerosis. All patients had pathologic CT and MRT findings; 4 different types of lesion were seen in MRT. In order to elucidate human genetic aspects and to demonstrate the underlying disease all children with epileptic disorders and also all patients without the full triad of symptoms should be examined by MRT.
Dewes
W
W
Funktionsbereich Kernspintomographie, Universitätskliniken des Saarlandes, Homburg/Saar, FRG.
Henkes
H
H
Richter
J
J
Kretschmer
A
A
Benz
P
P
Brill
G
G
D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed; D014402:Tuberous Sclerosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology
Tuberöse Sklerose: Erweiterung der Diagnostik durch MR-Tomographie und Computertomographie.