title: [Morphofunctional basis for disturbances of transport-trophic myocardial function in hypercholesterolemia].
abstract: Adaptive and pathologic changes limiting the myocardial circulation and changing the microvessel circulation are described in rabbits with alimentary hypercholesterolemia. The most important changes were the sludge-syndrome, multifactorial endotheliocyte deformity and capillary compression in the perivascular oedema, sclerosis and cardiomyocyte damage. Dyslipoproteinemia is shown to initiate the circulatory hypoxia and diffuse cardiosclerosis beyond the direct connection with atherosclerotic damage of the main heart arteries.
authors: A S
authors: AS
authors: Gavrish
mesh_terms: D000818:Animals; D001692:Biological Transport / Q000502:physiology; D002199:Capillary Permeability / Q000502:physiology; D009202:Cardiomyopathies / Q000473:pathology; D002791:Cholesterol, Dietary / Q000009:adverse effects*; D003326:Coronary Circulation / Q000502:physiology*; D004487:Edema / Q000473:pathology; D004730:Endothelium, Vascular / Q000473:pathology; D006937:Hypercholesterolemia / Q000209:etiology / Q000473:pathology*; D000860:Hypoxia / Q000473:pathology; D008055:Lipids / Q000097:blood; D008833:Microcirculation / Q000473:pathology; D011817:Rabbits; D012598:Sclerosis
chemical_list: D002791:Cholesterol, Dietary; D008055:Lipids
vernacular_title: Morphofunktsional'nye osnovy narusheniia transportno-troficheskogo funktsii miokarda pri giperkholesterinemii.