Minimal electrophoresis time for DNA sequencing.
This study presents a mathematical approach that allows one to determine the shortest electrophoresis time and migration path length required for DNA sequencing. The calculation was applied to the capillary electrophoresis of a DNA sequencing separation and showed that acceptable resolution could be obtained using a shorter path length than anticipated.
Aldroubi
A
A
Biomedical Engineering and Instrumentation Program, National Center for Research Resources, National Institutes of Health, Bethesda, MD 20892.
Garner
M M
MM
D004586:Electrophoresis / Q000379:methods*; D008962:Models, Theoretical; D017422:Sequence Analysis, DNA / Q000379:methods*; D013997:Time Factors