[Immunocorrection in destructive pancreatitis].
An immunocorrective effect of current methods of detoxication in experimental acute destructive pancreatitis was studied on 40 mongrel male dogs with body mass 13-15 kg. It was found that destructive pancreatitis is associated with a decrease in immunological reactivity, mainly in T-cell immunity component. Application of spleen xeno and ultraviolet irradiation of autoblood proved most effective as early treatment. On treatment day 3-7 immunological indices recovered and even increased after hemosorption.
Manucharov
N K
NK
Tavdidishvili
Iu D
IuD
Akhvlediani
E N
EN
Sychev
M D
MD
Tomaev
K B
KB
Kiladze
M M
MM
D000208:Acute Disease; D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology; D003131:Combined Modality Therapy / Q000379:methods; D004285:Dogs; D007111:Immunity, Cellular; D007167:Immunotherapy / Q000379:methods*; D007958:Leukocyte Count; D008297:Male; D010195:Pancreatitis / Q000276:immunology / Q000628:therapy*; D016060:Sorption Detoxification / Q000379:methods; D013601:T-Lymphocytes / Q000276:immunology
Immunokorrektsiia pri destruktivnom pankreatite.