title: Movement disorders in astrocytomas of the basal ganglia and the thalamus.
abstract: In a series of 225 patients with astrocytomas (grades I-IV) of the basal ganglia and the thalamus, 20 had a movement disorder. In all patients the histological diagnosis was verified by stereotactic biopsy. Tremor was observed in twelve patients, dystonia in eight, chorea in three, and chorea/ballismus and myoclonus in one. The tumour involved the thalamus in 16 patients. Corticospinal tract dysfunction was evident in 70% of the patients with movement disorders and in 73% of those without. Demographic, clinical, histological and neuroradiological data of the patients with a movement disorder were compared with the data of patients without. CT data yielded no differences with respect to the involvement of anatomical structures. Movement disorders were significantly associated with low-grade astrocytomas.
authors: Department of Neurosurgery, Albert-Ludwigs-Universität, Freiburg, Germany.
authors: J K
authors: JK
authors: Krauss
authors: F
authors: F
authors: Nobbe
authors: A K
authors: AK
authors: Wakhloo
authors: M
authors: M
authors: Mohadjer
authors: W
authors: W
authors: Vach
authors: F
authors: F
authors: Mundinger
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001254:Astrocytoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D001479:Basal Ganglia / Q000473:pathology; D001480:Basal Ganglia Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D001706:Biopsy; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009069:Movement Disorders / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D009460:Neurologic Examination; D013786:Thalamic Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D013788:Thalamus / Q000473:pathology; D014057:Tomography, X-Ray Computed