Pemphigoid gestationis--response to chemical oophorectomy with goserelin.
A 46-year-old caucasian female presented in January 1991 with a 17-year history of severe pemphigoid gestationis. She had been on systemic steroids for 10 years since her last pregnancy in 1981 and required doses of 20-80 mg prednisolone daily to control her disease. A chemical oophorectomy was induced using a new luteinizing hormone releasing hormone (LHRH) analogue known as goserelin. A complete remission occurred within 6 months of initiating this treatment and the systemic steroids were discontinued.
Garvey
M P
MP
St John's Dermatology Centre, St Thomas's Hospital, London, UK.
Handfield-Jones
S E
SE
Black
M M
MM
D005260:Female; D017273:Goserelin / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D010052:Ovariectomy / Q000379:methods; D010391:Pemphigoid, Bullous / Q000188:drug therapy* / Q000473:pathology
D017273:Goserelin