Prospective study in adults of splenic preservation after traumatic rupture.
Seventy-five adults with splenic injury were evaluated prospectively over 45 months to examine the possibility of splenic preservation. Haemodynamically unstable patients underwent surgery with the intent of splenic preservation. Stable patients received non-operative treatment regardless of the grade of splenic injury determined by ultrasonography and computed tomography. Thirty-seven patients required splenectomy and in 38 the organ was preserved (20 operative preservation, 18 non-operative treatment). Of 22 patients initially receiving non-operative treatment, there were four secondary haemorrhages after 7, 7, 10 and 13 days making surgery necessary. Three of these patients underwent splenectomy and in one the spleen was preserved by partial resection. After splenectomy four patients required reoperation because of rebleeding or for evacuation of a haematoma. Patients who had undergone splenectomy had a significantly increased infection rate (P < 0.005) compared with those in whom the spleen was preserved, even when patients were matched with respect to multiple trauma using the Injury Severity Score (P < 0.01).
Schweizer
W
W
Department of Visceral and Transplantation Surgery, University of Berne, Inselspital, Switzerland.
Böhlen
L
L
Dennison
A
A
Blumgart
L H
LH
D000293:Adolescent; D000328:Adult; D000368:Aged; D001424:Bacterial Infections; D005069:Evaluation Studies as Topic; D005260:Female; D006470:Hemorrhage; D006801:Humans; D015601:Injury Severity Score; D007431:Intraoperative Complications; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality; D011446:Prospective Studies; D012086:Reoperation; D013156:Splenectomy; D013158:Splenic Diseases; D013161:Splenic Rupture / Q000628:therapy*