[Histocompatibility antigens (HLA) in children with lipoid nephrosis].
Actual knowledge on the HLA relationship with the primary glomerulopathies, with particular reference to steroid - sensitive nephrosis of childhood, is surveyed. Occurrence of HLA B-8 and B-35 in this nephropathy has been investigated. The studies involved 47 patients aged between 3 and 15 years and 117 healthy children from Lower Silesian region. It has been showed, that HLA B-8 is present more frequently in sick children, than in healthy controls. The situation is reverse in case of HLA B-35 antigen. However, the difference is statistically insignificant. A probability of the lipid nephrosis sensitivity to corticosteroids can not be predicted on the base of the presence of these HLA antigens.
Zwolińska
D
D
Katedry i Kliniki Nefrologii Pediatrycznej AM we Wrocławiu.
Morawska
Z
Z
Makulska
I
I
Dmochowska
D
D
Jaśniak
K
K
Morawski
A
A
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D015797:HLA-B35 Antigen / Q000032:analysis*; D015795:HLA-B8 Antigen / Q000032:analysis*; D006801:Humans; D008297:Male; D009402:Nephrosis, Lipoid / Q000276:immunology*; D012016:Reference Values
D015797:HLA-B35 Antigen; D015795:HLA-B8 Antigen
Antygeny zgodności tkankowej (HLA) w nerczycy lipidowej u dzieci.