Fisher's syndrome without total ophthalmoplegia.
A 16-year-old boy with acute ophthalmoplegic polyneuritis (Fisher's syndrome) exhibited bilateral internal ophthalmoplegia, but only lateral rectus and superior oblique eye movements were affected. Gaze-evoked nystagmus was also present on left lateral gaze. Pupillary reflex recovered 7 weeks after onset, but neither cholinergic supersensitivity nor light-near dissociation were present during the recovery process. This is the first such case to be reported in which the site of the lesion responsible for the pupillomotor impairment was the Edinger-Westphal nucleus.
Igarashi
Y
Y
Department of Ophthalmology, Sapporo Medical College, Japan.
Takeda
M
M
Maekawa
H
H
Ohguro
H
H
Ohyachi
H
H
Ogasawara
K
K
D000293:Adolescent; D002524:Cerebellar Ataxia / Q000503:physiopathology*; D002799:Cholinergic Fibers / Q000502:physiology; D006801:Humans; D008297:Male; D008636:Mesencephalon / Q000503:physiopathology; D009460:Neurologic Examination; D009802:Oculomotor Nerve / Q000503:physiopathology; D009886:Ophthalmoplegia / Q000503:physiopathology*; D011115:Polyneuropathies / Q000503:physiopathology; D012025:Reflex, Pupillary / Q000502:physiology*; D013577:Syndrome