[Adaptability of the anti-hepatitis-B vaccine Recombivax HB to the Piazza protocol for the mass vaccination of newborn infants].
27 healthy babies born to HBsAg, antiHBs and antiHBc negative mothers were given three doses of hepatitis B vaccine "Recombivax HB" (5 micrograms/dose/0.5 ml) at 3, 5 and 11 months of age (Piazza's protocol). AntiHBs response was highly satisfactory. Since both in terms of seroconversion rate and of mean antiHBs titre immunogenicity of other hepatitis B vaccines given at 3, 5 and 11 months of age was already demonstrated, it is possible to conclude that Piazza's protocol is valid for all hepatitis B vaccines available in Italy and will certainly facilitate the compulsory hepatitis B vaccination in infants in Italy.
Piazza
M
M
Clinica delle Malattie Infettive, II Facoltà di Medicina e Chirurgia dell'Università di Napoli.
Abrescia
N
N
Picciotto
L
L
Cotugno
M
M
Vegnente
A
A
Iorio
R
R
Cimmino
L
L
D002353:Carrier State / Q000453:epidemiology; D005069:Evaluation Studies as Topic; D006509:Hepatitis B / Q000453:epidemiology / Q000517:prevention & control*; D006510:Hepatitis B Antibodies / Q000096:biosynthesis; D017325:Hepatitis B Vaccines / Q000008:administration & dosage* / Q000276:immunology; D006801:Humans; D007115:Immunization Schedule; D007223:Infant; D007558:Italy; D009313:National Health Programs; D015995:Prevalence; D014611:Vaccination; D014614:Vaccines, Synthetic / Q000008:administration & dosage* / Q000276:immunology
D006510:Hepatitis B Antibodies; D017325:Hepatitis B Vaccines; C075655:Recombivax HB; D014614:Vaccines, Synthetic
Adattabilità del vaccino anti-epatite B Recombivax HB allo "schema Piazza" per la vaccinazione di massa dei nuovi nati.