title: Prediction of acute renal failure following soft-tissue injury using the venous bicarbonate concentration.
abstract: Sixty-four patients with soft-tissue injuries were studied prospectively to determine whether an initial venous bicarbonate concentration (VBC) of less than 17 mmol/L would predict the development of myoglobin-induced acute renal failure. The VBC was > 17 mmol/L in 59 patients, seven of whom had myoglobinuria. All recovered without renal complications. The remaining five patients all had VBC < 17 mmol/L and four had myoglobinuria. Acute renal failure developed in four patients (p < 0.001). The VBC on hospital arrival was the most accurate predictor of these patients' risk for the development of acute renal failure following soft-tissue injury.
authors: Department of Surgery, University of Natal Medical School, Durban, South Africa.
authors: D J
authors: DJ
authors: Muckart
authors: M
authors: M
authors: Moodley
authors: A G
authors: AG
authors: Naidu
authors: A D
authors: AD
authors: Reddy
authors: K R
authors: KR
authors: Meineke
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000209:etiology*; D000293:Adolescent; D000328:Adult; D001639:Bicarbonates / Q000097:blood*; D003444:Crush Syndrome / Q000097:blood* / Q000150:complications*; D005260:Female; D005544:Forecasting; D006801:Humans; D008297:Male; D008875:Middle Aged; D009212:Myoglobinuria / Q000150:complications* / Q000209:etiology; D014949:Wounds, Nonpenetrating / Q000097:blood / Q000150:complications / Q000209:etiology
chemical_list: D001639:Bicarbonates