title: Acid-base changes in the running greyhound: contributing variables.
abstract: To determine the factors responsible for changes in [H+] during and after sprint exercise in the racing greyhound, Stewart's quantitative acid-base analysis was applied to arterial blood plasma samples taken at rest, at 8-s intervals during exercise, and at various intervals up to 30 min after a 402-m spring (approximately 30 s) on the track. [Na+], [K+], [Cl-], [total Ca], [lactate], [albumin], [Pi], PCO2, and pH were measured, and the [H+] was calculated from Stewart's equations. This short sprint caused all measured variables to change significantly. Maximal changes were strong ion difference decreased from 36.7 meq/l at rest to 16.1 meq/l; [albumin] increased from 3.1 g/dl at rest to 3.7 g/dl; PCO2, after decreasing from 39.6 Torr at rest to 27.9 Torr immediately prerace, increased during exercise to 42.8 Torr and then again decreased to near 20 Torr during most of recovery; and [H+] rose from 36.6 neq/l at rest to a peak of 76.6 neq/l. The [H+] calculated using Stewart's analysis was not significantly different from that directly measured. In addition to the increase in lactate and the change in PCO2, changes in [albumin], [Na+], and [Cl-] also influenced [H+] during and after sprint exercise in the running greyhound.
authors: Department of Anatomy and Physiology, Kansas State University, Manhattan 66506-5602.
authors: R L
authors: RL
authors: Pieschl
authors: P W
authors: PW
authors: Toll
authors: D E
authors: DE
authors: Leith
authors: L J
authors: LJ
authors: Peterson
authors: M R
authors: MR
authors: Fedde
mesh_terms: D000136:Acid-Base Equilibrium / Q000502:physiology*; D000693:Anaerobiosis; D000818:Animals; D001784:Blood Gas Analysis; D002245:Carbon Dioxide / Q000097:blood; D004285:Dogs / Q000502:physiology*; D004573:Electrolytes / Q000097:blood; D005260:Female; D006863:Hydrogen-Ion Concentration; D008297:Male; D010100:Oxygen / Q000097:blood; D005082:Physical Exertion / Q000502:physiology*
chemical_list: D004573:Electrolytes; D002245:Carbon Dioxide; D010100:Oxygen