title: Effect of a sunflower oil-supplemented diet on protein kinase activities of rat liver plasma membranes.
abstract: 1. The effect of a sunflower oil-enriched diet on plasma membrane-bound protein kinase C, protein kinase A, casein and tyrosine kinase activities was studied. 2. The diet induced an increase in the content of linoleic acid and a decrease in the content of palmitic acid. The anisotropy parameter (rs) of the fluorescence probe DPH and SDPH decreased strongly in the experimental group. 3. Protein kinase C was stimulated more than two times. Tyrosine kinase, protein kinase A and casein kinase activities were increased by 65, 57 and 40%, respectively. 4. We suggest that a more fluid lipid environment favours higher plasma membrane-bound protein kinase activities.
authors: Central Laboratory of Biophysics, Bulgarian Academy of Sciences, Sofia.
authors: N J
authors: NJ
authors: Gavrilova
authors: M S
authors: MS
authors: Setchenska
authors: M
authors: M
authors: Nikolova-Karakashian
authors: D H
authors: DH
authors: Petkova
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D004042:Dietary Fats, Unsaturated / Q000494:pharmacology*; D004789:Enzyme Activation / Q000187:drug effects; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D008563:Membrane Lipids / Q000378:metabolism; D010938:Plant Oils / Q000494:pharmacology*; D011493:Protein Kinase C / Q000378:metabolism; D011494:Protein Kinases / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D000074242:Sunflower Oil
chemical_list: D004042:Dietary Fats, Unsaturated; D008563:Membrane Lipids; D010938:Plant Oils; D000074242:Sunflower Oil; D011494:Protein Kinases; D011493:Protein Kinase C