6-H3 thymidine uptake in the central nervous system of newt following lesion and cold shock.
The uptake of 6-H3 thymidine in the optic tectum and the forebrain of the newt following injury to one of the two nervous areas, shows a marked proliferative response in the telencephalon in the presence of a lesion on the right optic tectum, and a poor response of the optic tectum after a lesion on the right telencephalic lobe. A similar proliferative response is also obtained when the specimens received only the cold shock. In both experimental conditions maximum uptake is obtained after 7 days. It is assumed that the matrix cells of the forebrain and the undifferentiated cells of the optic tectum respond differently to the regeneration factor released by the nervous tissue following a lesion or a cold shock.
Franceschini
V
V
Department of Biology, University of Bologna, Italy.
Del Grande
P
P
Minelli
G
G
Ciani
F
F
D000818:Animals; D003080:Cold Temperature; D004247:DNA / Q000096:biosynthesis*; D009416:Nerve Regeneration; D016548:Prosencephalon / Q000166:cytology / Q000378:metabolism / Q000502:physiology*; D013477:Superior Colliculi / Q000166:cytology / Q000378:metabolism / Q000502:physiology*; D013687:Telencephalon / Q000166:cytology / Q000378:metabolism / Q000502:physiology*; D013936:Thymidine / Q000378:metabolism*; D013997:Time Factors; D014316:Tritium; D014319:Triturus
D014316:Tritium; D004247:DNA; D013936:Thymidine