Hair removal by a depilatory does not affect survival in rodent experimental flaps.
The current study looked at the effect of topically applied hair depilatory agent Nair on flap survival. In a 10 x 3-cm dorsal rat flap model, there were no statistically significant differences in survival noted on postoperative day 7 between control skin and flaps receiving 6 to 24 minutes of Nair preoperatively. Therefore, hair depilation by Nair can be used safely in this model.
Angel
M F
MF
Division of Plastic Surgery, Johns Hopkins School of Medicine, Baltimore, MD 21205.
Jorysz
M
M
Schieren
G
G
Knight
K R
KR
O'Brien
B M
BM
D000279:Administration, Cutaneous; D000818:Animals; D006085:Graft Survival / Q000187:drug effects*; D006204:Hair Removal / Q000379:methods*; D008297:Male; D009336:Necrosis; D051381:Rats; D017208:Rats, Wistar; D016038:Skin Transplantation; D013864:Thioglycolates / Q000008:administration & dosage / Q000494:pharmacology*; D013997:Time Factors
D013864:Thioglycolates