Positive antinuclear antibody in atopic dermatitis.
Serum samples from atopic dermatitis (AD) patients were examined with two antinuclear antibody-detecting methods, using HEp-2 cells as substrate. 34.0% of 47 AD patients tested with FITC-conjugated polyvalent immunoglobulins (method 1) had positive antinuclear antibody (ANA). 26.3% of 57 AD patients examined with FITC-conjugated anti-IgG (method 2) had positive ANA. We found that AD patients who had facial lesions tended to have positive ANA, whereas severe AD patients tended to have high titres of ANA.
Taniguchi
Y
Y
Department of Dermatology, Mie University School of Medicine, Tsu, Japan.
Yamakami
A
A
Sakamoto
T
T
Nakamura
Y
Y
Okada
H
H
Tanaka
H
H
Mizutani
H
H
Shimizu
M
M
D000293:Adolescent; D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis*; D003876:Dermatitis, Atopic / Q000276:immunology*; D005148:Facial Dermatoses / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male
D000974:Antibodies, Antinuclear