Neuropsychological functioning in nonmentally retarded autistic individuals.
To investigate several neurobiological theories we evaluated the neuropsychological functioning of 15 non-mentally retarded autistic adolescents and young adults and 15 controls matched on age, gender, IQ, and race. The autistic subjects were found to perform less well than controls on measures of abstraction involving cognitive flexibility, verbal reasoning, complex memory, and complex language comprehension in the absence of significant differences on measures of attention, associative memory, and the rule-learning aspects of abstraction. These findings are most consistent with a generalized abnormality in complex information processing and would not support theories purporting fundamental deficits in attention or information acquisition.
Minshew
N J
NJ
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213.
Goldstein
G
G
Muenz
L R
LR
Payton
J B
JB
D000293:Adolescent; D000328:Adult; D001288:Attention / Q000502:physiology; D001321:Autistic Disorder / Q000523:psychology*; D003071:Cognition / Q000502:physiology; D006801:Humans; D007802:Language; D008297:Male; D008568:Memory / Q000502:physiology; D008606:Mental Processes / Q000502:physiology*; D009483:Neuropsychological Tests; D014888:Wechsler Scales