[Blood platelets, lipid peroxidation and antioxidants].
The paper reviews published data on the products of platelet lipid peroxidation, their role in blood coagulation as other physiological and pathological processes. The authors discuss the significance of anti-oxidants (selenium, glutathione peroxidase, reduced glutathione and vitamin E) in removing excessive hydroperoxides and thus in the control of platelet functional activity. Changes in platelet arachidonic acid metabolites and in antioxidants were found in a number of pathological conditions such as diabetes mellitus and cardiovascular diseases.
Kasjanovová
D
D
Výskumný ústav gerontológie, Malacky.
Macejka
J
J
D000818:Animals; D000975:Antioxidants; D001792:Blood Platelets / Q000378:metabolism*; D006801:Humans; D015227:Lipid Peroxidation; D010100:Oxygen / Q000502:physiology*
D000975:Antioxidants; D010100:Oxygen
Krvné dosticky, lipidová peroxidácia a antioxidanty.