Cell culture of macular epiretinal membranes.
To attempt to differentiate the cells of origin in epiretinal membranes, cells were cultured from an idiopathic epiretinal membrane and an epiretinal membrane that formed after successful repair of a retinal detachment. The cells exhibited a variety of forms. When the cells from the idiopathic epiretinal membrane were incubated with melanin from donor eyes a population of small cells accumulated the pigment, but the large, flat cells did not. The epiretinal membrane was not composed of a single cell type. Although a population of cells exists within epiretinal membranes, no one cell type could be identified as the cell type of origin.
MacDonald
I M
IM
Department of Ophthalmology, University of Ottawa.
Smith
C H
CH
Britton
W A
WA
D000368:Aged; D002478:Cells, Cultured; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D008543:Melanins / Q000378:metabolism; D008875:Middle Aged; D012160:Retina / Q000473:pathology*; D012163:Retinal Detachment / Q000473:pathology / Q000601:surgery; D014821:Vitrectomy
D008543:Melanins