Determination of trimethylamine and related aliphatic amines in human urine by head-space gas chromatography.
A rapid and simple assay procedure employing head-space gas chromatography has been developed for the routine quantification of volatile methylamines and stable trimethylamine N-oxide present in human urine. This assay will enable the rapid screening of patients and aid the diagnosis of fish odour syndrome.
Zhang
A Q
AQ
Department of Pharmacology and Toxicology, St. Mary's Hospital Medical School, Imperial College of Science, Technology and Medicine, Paddington, London, UK.
Mitchell
S C
SC
Ayesh
R
R
Smith
R L
RL
D000588:Amines / Q000652:urine*; D002849:Chromatography, Gas / Q000379:methods*; D006801:Humans; D008661:Metabolism, Inborn Errors / Q000652:urine; D008744:Methylamines / Q000652:urine*; D009812:Odorants
D000588:Amines; D008744:Methylamines; C023336:trimethylamine