Marchiafava-Bignami disease. A case studied by structural and functional brain imaging.
Marchiafava-Bignami disease (MBD) is a rare complication of chronic alcoholism. The clinical features, X-ray, CT and MRI findings are well documented. However, functional brain imaging has not been used in cases of MBD. We used single-photon emission computed tomography (SPECT) to monitor the regional cerebral blood flow in a patient suffering from a acute form of MBD, from which he subsequently recovered. Several abnormalities were found. A more frequent use of functional brain imaging in MBD could improve our knowledge of pathogenesis and prognosis for MBD.
Humbert
T
T
Service de Psychiatrie B1, Hôpital Gaston Doumergue, C.H.U., Nimes, France.
De Guilhermier
P
P
Maktouf
C
C
Grasset
G
G
Lopez
F M
FM
Chabrand
P
P
D000328:Adult; D000437:Alcoholism / Q000150:complications*; D001927:Brain Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D003337:Corpus Callosum / Q000000981:diagnostic imaging / Q000503:physiopathology*; D004569:Electroencephalography; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009460:Neurologic Examination; D011859:Radiography; D015899:Tomography, Emission-Computed, Single-Photon