title: Corneal endothelial irregularity with long-term contact lens wear.
abstract: A case is presented of a 49-year-old woman who has worn hard contact lenses for 26 years. Specular microscopy of the central corneal endothelium revealed marked bilateral polymegethism and a large coefficient of variation in cell size. Of greater significance was the presence of clumps of small cells. This may be related to the way the corneal endothelium responds to long-term anoxia.
authors: Tennent Institute of Ophthalmology, University of Glasgow, Scotland.
authors: R W
authors: RW
authors: Stevenson
authors: C M
authors: CM
authors: Kirkness
mesh_terms: D002452:Cell Count; D003261:Contact Lenses / Q000009:adverse effects*; D003316:Corneal Diseases / Q000209:etiology / Q000473:pathology; D004728:Endothelium, Corneal / Q000473:pathology*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008853:Microscopy; D008875:Middle Aged; D010101:Oxygen Consumption