title: Staphylococcal septicaemia complicating intracavernosal autoinjection therapy for impotence in a man with diabetes.
abstract: Intracavernosal injection of vasoactive drugs is a safe, effective, and commonly used treatment for impotence in diabetic men. In prospective studies infection has rarely occurred. We report a case of life-threatening Staphylococcal septicaemia complicating this treatment in a 61-year-old man with Type 2 diabetes, probably due to a combination of an unsterile technique and drug-induced priapism. Infection is a potential risk in diabetic men using intracavernosal injection therapy and those offered it should be informed of the importance of a scrupulous sterile technique and the need to seek urgent medical help for decompression if an erection persists for more than 4-6 h.
authors: University Department of Medicine, Southmead Hospital, Bristol, UK.
authors: V J
authors: VJ
authors: Parfitt
authors: R
authors: R
authors: Wong
authors: A
authors: A
authors: Dobbie
authors: M
authors: M
authors: Hartog
authors: J C
authors: JC
authors: Gingell
mesh_terms: D016470:Bacteremia / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology*; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D007172:Erectile Dysfunction / Q000188:drug therapy* / Q000209:etiology; D005436:Floxacillin / Q000627:therapeutic use; D005672:Fusidic Acid / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010208:Papaverine / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D010410:Penile Erection / Q000187:drug effects; D010413:Penis / Q000601:surgery; D011317:Priapism / Q000150:complications / Q000628:therapy; D012646:Self Administration / Q000009:adverse effects; D012772:Shock, Septic / Q000175:diagnosis / Q000209:etiology*; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D014521:Urethra / Q000601:surgery
chemical_list: D005436:Floxacillin; D005672:Fusidic Acid; D010208:Papaverine