[Analysis of photo-ablation products of excimer and erbium:YAG laser treated human corneas. Combined gas chromatography/mass spectroscopy].
The photoablation products from human cadaver corneas treated with an excimer laser (192 nm) or an erbium: YAG laser (2.94 microns) were qualitatively analyzed using a combined gas chromatography mass spectrometry (GC/MS) system. GC/MS is the most sensitive analyzing system in use today for molecules with a relative molecular mass of 40 to 400. More than 20 different types of molecules were detected; most of them were identified as alkanes. Comparison of the two types of laser showed larger fragments and fewer different types of molecules after excimer laser treatment than after erbium: YAG photoablation. We postulate that the smaller molecules after erbium: YAG treatment indicate a greater heat during photoablation than with excimer laser treatment.
Kahle
G
G
Universitätsklinikum Rudolf Virchow, Augenklinik, Berlin.
Städter
H
H
Seiler
T
T
Wollensak
J
J
D000473:Alkanes / Q000032:analysis*; D003315:Cornea / Q000473:pathology / Q000601:surgery*; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D053685:Laser Therapy / Q000295:instrumentation*; D008970:Molecular Weight
D000473:Alkanes
Analyse der Photoablationsprodukte von mit Excimer- und Erbium: YAG-Laser behandelten menschlichen Hornhäuten. Kombinierte Gaschromatographie/Massenspektroskopie.