[The effect of carnosine on hematopoietic stem cell activity in irradiated animals].
Carnosine given to adult animals together with potable water one day prior to gamma-irradiation or injected in a single intraperitoneal dose one hour after irradiation enhances colony formation by haemopoietic stem cells migrating from the bone marrow to the spleen. In young animals with a high colony-forming activity carnosine either decreases or does not influence at all the efficiency of colony production.
Mal'tseva
V V
VV
Sergienko
V V
VV
Stvolinskiĭ
S L
SL
D000818:Animals; D001854:Bone Marrow Cells; D002336:Carnosine / Q000494:pharmacology*; D006412:Hematopoietic Stem Cells / Q000187:drug effects*; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D013154:Spleen / Q000166:cytology; D014916:Whole-Body Irradiation
D002336:Carnosine
Vliianie karnozina na aktivnost' gemopoéticheskikh stvolovykh kletok u obluchennykh zhivotnykh.