[Significance of apolipoproteins A and B and the remaining lipid fractions as indicators of protein-calorie malnutrition in the elderly].
Effects of calorie/protein malnourishment have been studied on plasma concentrations of cholesterol, triglycerides, HDL-C, LDL-C and apolipoproteins A and B, in institutionalized elderly people, 53 males and 62 females, of whom 19 females and 12 males were malnourished. In malnourished patients, total cholesterol and LDL-C were significantly lower both in males and in females, but HDL-C was lower only in females. No significant differences in plasma triglycerides were found between the control and the malnourished groups. Apolipoprotein A showed no significant changes on malnourished males, but did show a significant lowering in malnourished females. On the opposite, apolipoprotein B was lower in males than in females. The lowering in cholesterol in malnourished patients leads us to think that this could be a early predictor of nutritional risk in the elderly.
Santi Cano
M J
MJ
Departamento de Medicina, Facultad de Medicina, Universidad de Cádiz.
Barba Chacón
A
A
Mangas Rojas
A
A
García Rojas
J F
JF
Millán Núñez-Cortés
J
J
Zamora Madaria
E
E
D000368:Aged; D000369:Aged, 80 and over; D001054:Apolipoproteins A / Q000032:analysis*; D001055:Apolipoproteins B / Q000097:blood*; D015415:Biomarkers; D002784:Cholesterol / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D011502:Protein-Energy Malnutrition / Q000097:blood*; D012737:Sex Factors; D014280:Triglycerides / Q000097:blood*
D001054:Apolipoproteins A; D001055:Apolipoproteins B; D015415:Biomarkers; D014280:Triglycerides; D002784:Cholesterol
Importancia de las apolipoproteínas A y B y las restantes fracciones lipídicas como indicadoras de desnutrición proteico-calórica en el anciano.