Ciprofloxacin upregulates interleukin-2 at the protein and mRNA levels in murine lymphocytes, but does not shorten graft survival in a rat cardiac allograft transplantation model.
Riesbeck
K
K
Department of Medical Microbiology, Lund University, Malmö General Hospital, Sweden.
Schatz
H
H
Ostraat
O
O
Ekberg
H
H
Forsgren
A
A
D000818:Animals; D015152:Blotting, Northern; D002939:Ciprofloxacin / Q000493:pharmacokinetics / Q000494:pharmacology*; D015342:DNA Probes; D006085:Graft Survival / Q000235:genetics* / Q000276:immunology; D016027:Heart Transplantation / Q000276:immunology*; D007376:Interleukin-2 / Q000235:genetics* / Q000502:physiology; D008214:Lymphocytes / Q000187:drug effects* / Q000276:immunology; D051379:Mice; D008815:Mice, Inbred Strains; D012333:RNA, Messenger / Q000235:genetics*; D051381:Rats; D011919:Rats, Inbred Strains; D015854:Up-Regulation / Q000187:drug effects / Q000235:genetics*
D015342:DNA Probes; D007376:Interleukin-2; D012333:RNA, Messenger; D002939:Ciprofloxacin