title: Saccade initiation and latency deficits after combined lesions of the frontal and posterior eye fields in monkeys.
abstract: 1. Monkeys were trained to perform horizontal visually guided saccades. Latency was measured before and after bilateral lesions of the frontal eye field (FEF) and after combined lesions of both the FEF and the posterior eye field. Destruction of either of these regions alone causes only modest deficits of eye movement, but destruction of both together produces profound oculomotor impairment. The results support the proposal that purposeful eye movements are controlled by a distributed corticocortical network that includes nodes in frontal and parieto-occipital regions.
authors: Department of Anatomy, University of Mississippi Medical Center, Jackson 39216.
authors: J C
authors: JC
authors: Lynch
mesh_terms: D000818:Animals; D002540:Cerebral Cortex / Q000033:anatomy & histology / Q000502:physiology; D005625:Frontal Lobe / Q000502:physiology; D008253:Macaca mulatta; D011930:Reaction Time; D012438:Saccades / Q000502:physiology*; D014794:Visual Fields / Q000502:physiology*