Biosynthesis of poly(3-hydroxyalkanoate) from amino acids.
It was found that an optically active copolyester, poly(3-hydroxybutyrate-co-3-hydroxyvalerate), denoted as P(3HB-co-3HV), is synthesized by Alcaligenes eutrophus H16 from several amino acids under various fermentation conditions. The optimum condition for the biosynthesis from one amino acid, threonine, was investigated and its biosynthetic pathway was discussed on the basis of the relation between the fermentation condition and the co-monomer composition of the produced polyesters.
Nakamura
K
K
Department of Biomolecular Engineering, Tokyo Institute of Technology, Japan.
Goto
Y
Y
Yoshie
N
N
Inoue
Y
Y
D000421:Alcaligenes / Q000378:metabolism; D000596:Amino Acids / Q000378:metabolism*; D001709:Biotechnology; D005285:Fermentation; D011091:Polyesters / Q000378:metabolism*; D013912:Threonine / Q000378:metabolism; D000094122:Polyhydroxybutyrates
D000596:Amino Acids; D011091:Polyesters; D013912:Threonine; C052620:poly(3-hydroxybutyrate)-co-(3-hydroxyvalerate); D000094122:Polyhydroxybutyrates