[Prognostic value of plasma levels of fibronectin in septic shock].
OBJECTIVE
The aim of the study was to assess possible changes in fibronectin serum levels in patients with septic shock and to analyze its usefulness as prognosis marker in this kind of shock.


METHODS
Fibronectin serum levels were determined in 20 patients with septic shock at 1, 3, 6, 12, 24 and 72 hours after the diagnosis was made.


RESULTS
Serum level of fibronectin drops between 6 and 24 hours after shock starts, reaching its lower value around hour 12. The level recovered after 24 hours in those cases with good clinical evolution, but not in patients with bad outcomes.


CONCLUSIONS
The analysis of fibronectin plasma level is a good prognostic marker for predicting survival in patients with septic shock.
Hortells
J L
JL
Departamento de Medicina, Hospital Clínico Universitario, Zaragoza.
Ibáñez Estella
J A
JA
Pérez de Viñaspre
S
S
Sánchez Ibáñez
A
A
González Barrio
I
I
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005353:Fibronectins / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D011446:Prospective Studies; D012772:Shock, Septic / Q000097:blood* / Q000401:mortality; D016019:Survival Analysis
D005353:Fibronectins
Valor pronóstico de los niveles plasmáticos de fibronectina en el shock séptico.