title: Relief of presumed compression in oligohydramnios: amnioinfusion does not affect umbilical artery Doppler waveforms.
abstract: The suggestion that amnioinfusion improves umbilical artery Doppler indices of downstream resistance in oligohydramnios by relieving cord compression was investigated by obtaining waveforms before and immediately after amnioinfusion in 16 pregnancies with severe oligohydramnios. There was no significant difference in the change in umbilical artery pulsatility index (PI) between 11 pregnancies in which amniotic fluid volume was restored (mean delta PI = -0.07, 95% confidence interval -0.17 to +0.07), and 5 pregnancies in which immediate vaginal leakage of infused fluid prevented restitution of amniotic fluid volume. Fetal heart rate did not change significantly in either group. End-diastolic frequencies did not return with restitution of amniotic fluid volume in the 2 pregnancies in which they were absent before infusion (absent in 1, reverse in 1). This study suggests that restitution of amniotic fluid volume in human pregnancies complicated by severe oligohydramnios does not acutely alter the umbilical artery PI.
authors: Royal Postgraduate Medical School, Institute of Obstetrics and Gynaecology, Queen Charlotte's and Chelsea Hospital, London, UK.
authors: N M
authors: NM
authors: Fisk
authors: C R
authors: CR
authors: Welch
authors: D
authors: D
authors: Ronderos-Dumit
authors: J I
authors: JI
authors: Vaughan
authors: U
authors: U
authors: Nicolini
authors: C H
authors: CH
authors: Rodeck
mesh_terms: D000650:Amnion; D000653:Amniotic Fluid / Q000502:physiology*; D005260:Female; D006340:Heart Rate, Fetal; D006801:Humans; D016104:Oligohydramnios / Q000503:physiopathology / Q000628:therapy*; D011247:Pregnancy; D012965:Sodium Chloride / Q000008:administration & dosage / Q000627:therapeutic use*; D014463:Ultrasonography; D014469:Umbilical Arteries / Q000000981:diagnostic imaging*
chemical_list: D012965:Sodium Chloride