title: [Comparison of results of echo-dobutamine and ECG-dobutamine tests in the diagnosis of coronary disease].
abstract: The aim of the study was to compare the results of 2D-Echocardiographic (ECHO) vs 12-lead Electrocardiographic (ECG) monitoring during Dobutamine (DOB) infusion performed as a stress test in patients referred for the evaluation of chest pain of suspected ischemic origin. Fourty-seven consecutive patients, 40 m and 7 f, mean age 52 +/- 9 years, were studied after interruption of any antianginal therapy. DOB was infused in 5-minute stages with incremental doses of 5 mcg/kg/min up to a maximal dose of 40 mcg/kg/min. 2D-ECHO monitoring could not be performed in 3 out of 47 patients because of a poor acoustic window. Thus, the overall feasibility was 94% for 2D-ECHO DOB test vs 100% for ECG DOB test (p = ns). The ECG and 2D-ECHO findings were compared in the remaining 44 patients. Criteria for positivity were: transient regional dyssynergy absent or of lesser degree in the baseline examination for 2D-ECHO; ST-segment shift > 0.1 mV from baseline for ECG. The test was stopped when a regional wall motion abnormality developed even in the absence of significant ECG changes. Angiographically assessed coronary artery disease (CAD) was considered significant when a > 50% reduction of the luminal diameter in at least 1 major coronary vessel occurred. There were 10/44 patients with no significant CAD and 34/44 patients with CAD; 16 had single, 18 double or triple and/or left main vessel disease.(ABSTRACT TRUNCATED AT 250 WORDS)
authors: Divisione di Cardiologia, IRCCS-Policlinico S. Matteo, Università degli studi di Pavia.
authors: L
authors: L
authors: Lanzarini
authors: M
authors: M
authors: Previtali
authors: M
authors: M
authors: Ferrario
authors: A
authors: A
authors: Mussini
authors: A
authors: A
authors: Poli
authors: R
authors: R
authors: Fetiveau
authors: C
authors: C
authors: Montemartini
mesh_terms: D000328:Adult; D003327:Coronary Disease / Q000175:diagnosis*; D004280:Dobutamine; D004452:Echocardiography; D004562:Electrocardiography; D005069:Evaluation Studies as Topic; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D004280:Dobutamine
vernacular_title: Confronto fra i risultati dei test eco-dobutamina ed ecg-dobutamina per la diagnosi di malattia coronarica.