Molecular characterization of a putative peroxidase gene of Drosophila melanogaster.
We have identified genomic clones and corresponding cDNAs that encode a putative peroxidase of Drosophila melanogaster. The gene (DmPO) appears as a single copy gene located on the third chromosome at position 89 D/E. It is interrupted by seven small introns and one unusually large 5' intron (about 11 kb). Sequence analysis of the cDNA showed an open reading frame of 690 amino acids resulting in a protein of 77 kDa. The deduced amino acid sequence reveals an overall homology to myeloeosinophil and thyroid peroxidase, a human superfamily of peroxidases.
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Institut für Molekulare Genetik, Universität Heidelberg, Germany.
Wiedemann
M
M
Kontermann
R
R
Petersen
G
G
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015139:Blotting, Southern; D002874:Chromosome Mapping; D004247:DNA / Q000235:genetics / Q000302:isolation & purification; D004331:Drosophila melanogaster / Q000201:enzymology* / Q000235:genetics*; D008969:Molecular Sequence Data; D010544:Peroxidases / Q000235:genetics*; D015183:Restriction Mapping; D012469:Salivary Glands / Q000166:cytology / Q000201:enzymology; D017386:Sequence Homology, Amino Acid
D004247:DNA; D010544:Peroxidases