Neuropsychiatric systemic lupus erythematosus in elderly people: a case series.
Five elderly patients presenting with neuropsychiatric systemic lupus erythematosus were referred to the sectorised psychiatry service of the department of health care of the elderly. They represented 2% of patients admitted over a period of two years. Two patients presented with a subacute confusional state, two with dementia, and one with depression. Three patients responded well to treatment. This suggests that systemic lupus erythematosus (SLE) is more common in elderly people than was originally thought and is a potentially treatable cause of organic brain disorder. The absence of reports of elderly patients with SLE is likely to be due to the continued application of the American Rheumatism Association's revised 1982 classification criteria, which are inappropriate for this population.
Dennis
M S
MS
Department of Health Care of the Elderly, Queen's Medical Centre, Nottingham.
Byrne
E J
EJ
Hopkinson
N
N
Bendall
P
P
D000368:Aged; D000369:Aged, 80 and over; D001379:Azathioprine / Q000627:therapeutic use; D003221:Confusion / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology; D003704:Dementia / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D008297:Male; D019965:Neurocognitive Disorders / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology; D011239:Prednisolone / Q000627:therapeutic use
D011239:Prednisolone; D001379:Azathioprine