Evidence that the increase in striatal c-fos following acute high-dose caffeine is not due to direct interaction with striatal adenosine receptors.
Johansson
B
B
Farmakologiska Institutionen, Karolinska Institute, Stockholm, Sweden.
Svenningsson
P
P
Adén
U
U
Lindström
K
K
Fredholm
B B
BB
D000241:Adenosine / Q000037:antagonists & inhibitors; D000818:Animals; D002110:Caffeine / Q000008:administration & dosage*; D003342:Corpus Striatum / Q000187:drug effects* / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D016762:Genes, fos / Q000187:drug effects*; D058914:Purinergic Antagonists; D011799:Quinazolines / Q000494:pharmacology; D012333:RNA, Messenger / Q000187:drug effects / Q000378:metabolism; D051381:Rats; D014230:Triazoles / Q000494:pharmacology; D014970:Xanthines / Q000494:pharmacology
D058914:Purinergic Antagonists; D011799:Quinazolines; D012333:RNA, Messenger; D014230:Triazoles; D014970:Xanthines; D002110:Caffeine; C051360:1,3-dipropyl-8-cyclopentylxanthine; D000241:Adenosine; C052410:9-chloro-2-(2-furyl)-(1,2,4)triazolo(1,5-c)quinazolin-5-imine