[The effect of nicergoline on the systemic and cerebral hemodynamics of patients with circulatory encephalopathy and an atherosclerotic lesion of the major cerebral arteries].
The Evans blue dilution method and ultrasound dopplerography were used to study the effect of nicergolin on the systemic and cerebral hemodynamics in 31 patients with dyscirculatory encephalopathy against the background of atherosclerotic lesions of the major head arteries. It was established that nicergolin reduces the arterial pressure, diminishes the minute blood volume, cardiac and stroke indices, increases the specific peripheral vascular resistance, the linear blood flow velocity prevailingly in the stenosed major head arteries, results in a regression of the subjective and objective neurological symptomatology. Considering the cardiodepressive effect of nicergolin, this agent is indicated in patients with the hyperkinetic type of the systemic hemodynamics.
Ishchenko
M M
MM
Shkrobot
S I
SI
D000328:Adult; D000368:Aged; D002560:Cerebrovascular Circulation / Q000187:drug effects / Q000502:physiology; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D004341:Drug Evaluation; D004453:Echoencephalography; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D002537:Intracranial Arteriosclerosis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009530:Nicergoline / Q000627:therapeutic use*; D012074:Remission Induction
D009530:Nicergoline
Vliianie nitsergolina na sistemnuiu i tserebral'nuiu gemodinamiku u bol'nykh s distsirkuliatornoĭ éntsefalopatieĭ na fone ateroskleroticheskogo porazheniia magistral'nykh arteriĭ golovy