title: Characterization of the gene encoding human pituitary-specific transcription factor, Pit-1.
abstract: Pit-1 is a pituitary-specific transcription factor that binds to and transactivates promoters of growth hormone- and prolactin-encoding genes. A chromosomal gene related to human Pit-1 isolated from human gene libraries was over 14 kb long and split into six exons. All of the splice donor and acceptor sites conformed to the GT/AG rule. The gene was mapped to human chromosome region 3p11.
authors: Department of Pediatrics, Kumamoto University School of Medicine, Japan.
authors: K
authors: K
authors: Ohta
authors: Y
authors: Y
authors: Nobukuni
authors: H
authors: H
authors: Mitsubuchi
authors: T
authors: T
authors: Ohta
authors: T
authors: T
authors: Tohma
authors: Y
authors: Y
authors: Jinno
authors: F
authors: F
authors: Endo
authors: I
authors: I
authors: Matsuda
mesh_terms: D001483:Base Sequence; D002874:Chromosome Mapping; D002893:Chromosomes, Human, Pair 3; D004247:DNA; D004268:DNA-Binding Proteins / Q000235:genetics*; D005091:Exons; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D008969:Molecular Sequence Data; D050817:Transcription Factor Pit-1; D014157:Transcription Factors / Q000235:genetics*
chemical_list: D004268:DNA-Binding Proteins; C494187:POU1F1 protein, human; D050817:Transcription Factor Pit-1; D014157:Transcription Factors; D004247:DNA