Review of drug-induced acute interstitial nephritis.
Drug-induced acute interstitial nephritis (AIN) is a rare, potentially correctable cause of acute renal failure. Early recognition and appropriate therapy are essential to its management. Several drugs have been associated with the development of AIN, including antibiotics and nonsteroidal antiinflammatory, agents, all with characteristic mechanisms of toxicity.
Murray
K M
KM
College of Pharmacy, University of South Carolina, Columbia.
Keane
W R
WR
D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D000890:Anti-Infective Agents / Q000009:adverse effects; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D024841:Fluoroquinolones; D006801:Humans; D007769:Lactams; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D013997:Time Factors
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D024841:Fluoroquinolones; D007769:Lactams