Papillary peritoneal carcinomatosis after prophylactic oophorectomy.
Prophylactic oophorectomy has been recommended in patients with a strongly positive family history for ovarian carcinoma. A patient with a strongly positive family history underwent a prophylactic oophorectomy and, 5 years later, developed a primary peritoneal papillary serous adenocarcinoma. A prophylactic oophorectomy does not afford complete protection in some patients with familial ovarian cancer syndrome. Any tissue derived from the coelomic epithelium may potentially undergo multifocal malignant transformation.
Kemp
G M
GM
Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk, Virginia 23507.
Hsiu
J G
JG
Andrews
M C
MC
D003536:Cystadenocarcinoma / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000235:genetics / Q000473:pathology / Q000517:prevention & control*; D010052:Ovariectomy; D010534:Peritoneal Neoplasms / Q000473:pathology*