Disseminated cutaneous sporotrichosis associated with anergic immuno-suppression due to miliary tuberculosis.
A 52-years-old policeman suffering from tuberculous meningitis, developed pseudo-umbilicated nodular skin lesions which increased rapidly in size during the course of his illness. Histology revealed cutaneous sporotrichosis. Human immuno-deficiency virus infection was excluded by absence of history of exposure and repeated negative serological test for HIV antibodies. The tuberculin test was also negative. Anti-tuberculous therapy failed to prevent a fatal outcome 3 months after admission to hospital. The possibility that the usually presentation of disseminated cutaneous sporotrichosis was an opportunistic infection facilitated by immuno-deficiency accompanying anergy of miliary tuberculosis is discussed.
Addy
J H
JH
University of Ghana Medical School Accra.
D001706:Biopsy; D006801:Humans; D016867:Immunocompromised Host / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D011193:Potassium Iodide / Q000627:therapeutic use; D013174:Sporotrichosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014391:Tuberculosis, Miliary / Q000150:complications* / Q000188:drug therapy / Q000276:immunology
D011193:Potassium Iodide