title: Superficial perineal leiomyosarcoma in an adolescent female and a review of the literature including vulvar leiomyosarcomas.
abstract: Superficial perineal leiomyosarcomas are rare, with only three previously reported examples. We encountered a superficial (deep subcutaneous) perineal leiomyosarcoma in a 17-year-old female. At follow-up two years after a wide excision, there were no signs of recurrence. The tumour was well differentiated and showed immunoreactivity for alpha-smooth muscle actin and desmin. A review of the literature on superficial leiomyosarcomas indicates that superficial perineal leiomyosarcomas may be more aggressive than superficial leiomyosarcomas in general. As the presented tumour occurred in a female, it was compared with vulvar leiomyosarcomas.
authors: Institute of Pathology, Aalborg Hospital, Denmark.
authors: A
authors: A
authors: Grove
authors: S
authors: S
authors: Backman Nøhr
mesh_terms: D000293:Adolescent; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology* / Q000628:therapy; D010502:Perineum; D012983:Soft Tissue Neoplasms / Q000473:pathology* / Q000628:therapy; D014846:Vulvar Neoplasms / Q000473:pathology*