title: Quantification of the ocular response to treatment in posterior uveitis.
abstract: Twenty patients with posterior uveitis were studied by anterior segment fluorophotometry to determine whether there was a relationship between the degree of breakdown of the blood-aqueous barrier and the clinical recovery of posterior uveitis. In individual eyes the degree of breakdown and recovery of the blood-aqueous barrier (as measured by changes in the anterior chamber fluorescein concentration) followed the resolution and relapse of disease making it possible to quantify the ocular response to treatment.
authors: Department of Ophthalmology, St Thomas' Hospital, London, UK.
authors: V M
authors: VM
authors: Ferguson
authors: D J
authors: DJ
authors: Spalton
mesh_terms: D000328:Adult; D000869:Anterior Eye Segment / Q000378:metabolism; D001082:Aqueous Humor / Q000378:metabolism; D001693:Biological Transport, Active; D001769:Blood / Q000378:metabolism; D002648:Child; D005260:Female; D019793:Fluorescein; D005452:Fluoresceins / Q000378:metabolism; D015590:Fluorophotometry; D005500:Follow-Up Studies; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D015866:Uveitis, Posterior / Q000188:drug therapy* / Q000378:metabolism*; D014792:Visual Acuity
chemical_list: D005452:Fluoresceins; D007166:Immunosuppressive Agents; D019793:Fluorescein