title: A case-control study of benign ovarian tumours.
abstract: OBJECTIVE
  The aim was to investigate the association between reproductive, contraceptive, and menstrual factors and risk of benign ovarian tumours.
  
  
  METHODS
  This was a case-control study carried out in six London Hospitals. An interviewer administered questionnaire was used.
  
  
  METHODS
  62 women with a benign epithelial ovarian neoplasm, 37 women with a functional ovarian cyst, and 20 women with a dermoid cyst presenting between 1983 and 1985, together with 132 controls, took part in the study.
  
  
  RESULTS
  On average, women with a benign epithelial ovarian neoplasm were older than those with a functional ovarian cyst, who in turn were older than those with a dermoid cyst. Nulliparity and infertility were associated with an increased risk, and multiparity with a reduced risk, of benign epithelial ovarian neoplasms. Infertility and pelvic inflammatory disease were associated with increased risks of functional and dermoid cysts. Recent use of oral contraceptives was associated with a reduced risk of all three tumour types.
  
  
  CONCLUSIONS
  The findings suggest that the aetiology of ovarian cysts and benign epithelial ovarian neoplasms may differ. The aetiology of benign and malignant epithelial ovarian neoplasms may be similar, however, since some risk factors are shared.
authors: Epidemiological Monitoring Unit, London School of Hygiene and Tropical Medicine, United Kingdom.
authors: M
authors: M
authors: Booth
authors: V
authors: V
authors: Beral
authors: N
authors: N
authors: Maconochie
authors: L
authors: L
authors: Carpenter
authors: C
authors: C
authors: Scott
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D016022:Case-Control Studies; D003276:Contraceptives, Oral / Q000009:adverse effects; D003884:Dermoid Cyst / Q000209:etiology; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000150:complications; D008572:Menarche; D008875:Middle Aged; D010048:Ovarian Cysts / Q000209:etiology; D010051:Ovarian Neoplasms / Q000209:etiology*; D010298:Parity; D000292:Pelvic Inflammatory Disease / Q000150:complications; D012307:Risk Factors
chemical_list: D003276:Contraceptives, Oral