In situ two- and three-color immunofluorescence staining of mucosal T-cells in celiac disease. Increase of TCR gamma/delta+CD8- and TCR alpha/beta+CD45R0+ intraepithelial lymphocytes and IL-2R+ TCR alpha/beta+CD4+CD45R0+ lamina propria lymphocytes.
Halstensen
T S
TS
Laboratory for Immunohistochemistry and Immunopathology (LIIPAT), Rikshospitalet, University of Oslo, Norway.
Scott
H
H
Farstad
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IN
Michaelsen
T E
TE
Brandtzaeg
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P
D017252:CD3 Complex / Q000032:analysis; D015704:CD4 Antigens / Q000032:analysis; D002446:Celiac Disease / Q000276:immunology / Q000473:pathology*; D003116:Color; D005455:Fluorescent Antibody Technique; D006801:Humans; D007413:Intestinal Mucosa / Q000276:immunology / Q000473:pathology*; D017493:Leukocyte Common Antigens / Q000032:analysis; D016693:Receptors, Antigen, T-Cell, alpha-beta / Q000032:analysis; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000032:analysis; D015375:Receptors, Interleukin-2 / Q000032:analysis; D016176:T-Lymphocyte Subsets / Q000737:chemistry / Q000276:immunology / Q000473:pathology*
D017252:CD3 Complex; D015704:CD4 Antigens; D016693:Receptors, Antigen, T-Cell, alpha-beta; D016692:Receptors, Antigen, T-Cell, gamma-delta; D015375:Receptors, Interleukin-2; D017493:Leukocyte Common Antigens