Focal dystonia secondary to cavernous angioma of the basal ganglia: case report and review of the literature.
The case of a young woman with focal dystonia of the hand due to a cavernous angioma of the basal ganglia is presented. The lesion involved the anterior third of the lentiform nucleus and a large portion of white matter anterior to this nucleus and lateral to the head of the caudate, as shown by magnetic resonance imaging; it was completely removed through a computed tomography-assisted stereotactic craniotomy by microsurgical technique, resulting in the cure of the patient. These facts support the pathophysiological hypothesis of a disruption of the striatopallidothalamic projection to the premotor cortex as the cause of symptomatic dystonia. A review of the reported cases of cavernous angiomas of the deep cerebral gray nuclei shows that this is the first case of cavernous angioma associated with movement disorder.
Lorenzana
L
L
Seccion de Neurocirugía, Hospital Universitario Infanta Cristina, Universidad de Extremadura, Badajoz, Spain.
Cabezudo
J M
JM
Porras
L F
LF
Polaina
M
M
Rodriguez-Sanchez
J A
JA
Garcia-Yagüe
L M
LM
D000328:Adult; D001479:Basal Ganglia / Q000473:pathology; D001480:Basal Ganglia Diseases / Q000150:complications* / Q000473:pathology / Q000601:surgery; D001932:Brain Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D004421:Dystonia / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D005260:Female; D006392:Hemangioma, Cavernous / Q000150:complications* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D009460:Neurologic Examination; D011183:Postoperative Complications / Q000175:diagnosis; D013238:Stereotaxic Techniques; D014057:Tomography, X-Ray Computed