Gastric emptying of carbohydrate--medium chain triglyceride suspensions at rest.
Nine male volunteers participated in 4 gastric emptying (GE) tests of liquid equicaloric mixtures of CHO (maltodextrins) and MCT of the following composition (% CHO-% MCT): Drink (Dr) 1:70%-30%, Dr2: 80%-20%, Dr3: 90%-10%, Dr4: 100%-0%. GE was measured at rest for 90 min according to the modified double sampling technique. GE rate, expressed as t1/2 (SEM), was 23 (2.3), 24 (1.6), 27 (2.2) and 36 (2.9) min, respectively, from drink 1 to drink 4. Statistical analysis showed that all MCT containing drinks emptied faster than the 100% CHO drink. Two mechanisms may explain this observation: 1) the CHO content and osmolality increases from Dr 1 to Dr 4 (both are regulators of GE); 2) MCT may not inhibit GE as common fat does, due to a better water solubility and absorption in the small intestine, resulting in a decreased duodenal-gastric feedback.
Beckers
E J
EJ
Dept. Human Biology, Nutrition Research Centre, Rijksuniversiteit, Limburg, Maastricht, The Netherlands.
Jeukendrup
A E
AE
Brouns
F
F
Wagenmakers
A J
AJ
Saris
W H
WH
D000328:Adult; D004040:Dietary Carbohydrates / Q000494:pharmacology*; D004041:Dietary Fats / Q000494:pharmacology*; D015444:Exercise / Q000502:physiology; D005746:Gastric Emptying / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D008297:Male; D009994:Osmolar Concentration; D013997:Time Factors; D014280:Triglycerides / Q000494:pharmacology*
D004040:Dietary Carbohydrates; D004041:Dietary Fats; D014280:Triglycerides