title: IgG subclasses distribution in immunoglobulin preparations for intravenous use.
abstract: The levels of IgG subclasses were determined, by radial immunodiffusion using monoclonal antibodies, in 16 production batches of two human immunoglobulin preparations for intravenous use--Immunovenin and Immunovenin-intact. While the partially degraded preparation--Immunovenin contained exclusively IgG1, the subclass distribution in Immunovenin-intact was close to that observed in normal human serum.
authors: Institute of Infectious and Parasitic Diseases, Sofia, Bulgaria.
authors: L G
authors: LG
authors: Bozadjiev
authors: I L
authors: IL
authors: Bineva
authors: T L
authors: TL
authors: Vassilev
mesh_terms: D002850:Chromatography, Gel; D002852:Chromatography, Ion Exchange; D006801:Humans; D005779:Immunodiffusion; D007074:Immunoglobulin G / Q000032:analysis* / Q000145:classification; D016756:Immunoglobulins, Intravenous / Q000737:chemistry* / Q000302:isolation & purification; D011092:Polyethylene Glycols
chemical_list: D007074:Immunoglobulin G; D016756:Immunoglobulins, Intravenous; D011092:Polyethylene Glycols