title: Diffuse Lewy body disease presenting with supranuclear gaze palsy, parkinsonism, and dementia: a case report.
abstract: A 67-year-old man with a family history of parkinsonism had visual complaints due to difficulty in convergence, which was followed 2 years later by development of bradykinesia and rigidity. The diagnosis of Steele-Richardson-Olszewski syndrome was made on the basis of a supranuclear gaze palsy, bradykinesia, rigidity, and poor response to levodopa. However, subsequent neuropathological examination revealed diffuse Lewy body disease with no evidence of neurofibrillary tangles involving either subcortical or brain stem structures.
authors: Parkinson's Disease Society Brain Bank, Institute of Neurology, London, England.
authors: V M
authors: VM
authors: de Bruin
authors: A J
authors: AJ
authors: Lees
authors: S E
authors: SE
authors: Daniel
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis / Q000473:pathology; D001921:Brain / Q000473:pathology; D003704:Dementia / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005133:Eye Movements / Q000502:physiology*; D006801:Humans; D016631:Lewy Bodies / Q000648:ultrastructure; D008297:Male; D009460:Neurologic Examination; D010300:Parkinson Disease / Q000175:diagnosis* / Q000473:pathology; D010302:Parkinson Disease, Secondary / Q000175:diagnosis* / Q000473:pathology; D013494:Supranuclear Palsy, Progressive / Q000175:diagnosis* / Q000473:pathology