[Study of selegiline and related compounds with x-ray diffraction].
Selegiline and its parent compounds were studied by X-ray diffraction. It was established that the racemates of primary and secondary amines (p-fluoro-amphetamine, methamphetamine, p-fluoro-methamphetamine) hydrochloride do not form racemic compounds but crystalline as conglomerates, at the same time tertiary amines like selegiline and p-fluoro-selegiline hydrochlorides do. The crystalline structure of five enantiomeric hydrochlorides were determined, the CPhe-C-C-N torsion angle is anti-periplanar in all cases but in p-fluoro-amphetamine where it is gauche.
Simon
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K
Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt., Budapest.
Böcskei
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Z
Török
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D000662:Amphetamines / Q000737:chemistry; D008958:Models, Molecular; D008968:Molecular Conformation; D012642:Selegiline / Q000031:analogs & derivatives* / Q000737:chemistry*; D014961:X-Ray Diffraction
D000662:Amphetamines; D012642:Selegiline
Selegilin és rokon vegyületek vizsgálata röntgendiffrakcióval.