title: Improvement of clinical and MRI findings in a boy with adrenoleukodystrophy by dietary erucic acid therapy.
abstract: A 5-year-old boy with adrenoleukodystrophy, with clinical symptoms of visual, mental and motor disturbances which progressed rapidly, was treated with Lorenzo's oil consisting 1 volume of glyceryl trierucate and 4 volumes of glyceryl trioleate. Five months after initiation of this therapy, ability to swallow was enhanced and T2-weighted magnetic resonance imaging of the brain revealed regression of high intensity area of the parieto-occipital white matter.
authors: Department of Pediatrics, Shizuoka Saiseikai General Hospital, Japan.
authors: K
authors: K
authors: Maeda
authors: Y
authors: Y
authors: Suzuki
authors: S
authors: S
authors: Yajima
authors: J
authors: J
authors: Asano
authors: S
authors: S
authors: Yamaguchi
authors: N
authors: N
authors: Matsumoto
authors: J
authors: J
authors: Borel
authors: H W
authors: HW
authors: Moser
authors: T
authors: T
authors: Orii
mesh_terms: D000326:Adrenoleukodystrophy / Q000178:diet therapy* / Q000473:pathology / Q000503:physiopathology; D001921:Brain / Q000473:pathology; D002675:Child, Preschool; D004042:Dietary Fats, Unsaturated / Q000627:therapeutic use*; D004338:Drug Combinations; D004883:Erucic Acids / Q000627:therapeutic use*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D014304:Triolein / Q000627:therapeutic use*
chemical_list: D004042:Dietary Fats, Unsaturated; D004338:Drug Combinations; D004883:Erucic Acids; C079420:Lorenzo's oil; D014304:Triolein