Translocations (17;20) in colorectal adenocarcinomas.
We describe new recurrent chromosome translocations (17;20) observed in 3 of 19 colorectal tumors. Two of them were identical: der(20)t(17;20)(q21;p12), resulting in the loss of 17(pter-->q21) and the third was a dicentric dic(17;20)(p11;p12). A similar dicentric was described previously in one tumor [1], but we report der(20)t(17;20)(q21;p12) for the first time.
Fleischman
E W
EW
Laboratory of Cytogenetics, Russian Academy of Medical Sciences, Moscow.
Konstantinova
L N
LN
Perevozchikov
A G
AG
Knisch
V I
VI
D000230:Adenocarcinoma / Q000235:genetics*; D000328:Adult; D002886:Chromosomes, Human, Pair 17; D002890:Chromosomes, Human, Pair 20; D015179:Colorectal Neoplasms / Q000235:genetics*; D005260:Female; D006801:Humans; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D014178:Translocation, Genetic