title: [The use of acetylcysteine in the combined treatment of patients with acute 1,2-dichloroethane poisoning].
abstract: The authors analyse the use of acetylcysteine as specific antidote treatment in 37 patients with acute 1,2-dichlorethane (DCE) poisoning. Administration of dichlorethane did not produce any determining effect on the outcome of the treatment in critical and irreversible concentration of DCE in the blood. The main component in complex therapy is early hemosorption. Acetylcystein may be used in the complex treatment of acute DCE intoxications after early extracorporal detoxication with the purpose of reducing the severity of troxic of hepatopathies.
authors: O V
authors: OV
authors: Kurashov
authors: V A
authors: VA
authors: Trotsevich
mesh_terms: D000111:Acetylcysteine / Q000008:administration & dosage*; D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000931:Antidotes / Q000008:administration & dosage*; D003131:Combined Modality Therapy; D005025:Ethylene Dichlorides / Q000097:blood / Q000506:poisoning*; D006801:Humans; D008875:Middle Aged; D011041:Poisoning / Q000097:blood / Q000628:therapy; D016060:Sorption Detoxification / Q000379:methods; D013997:Time Factors
chemical_list: D000931:Antidotes; D005025:Ethylene Dichlorides; C024565:ethylene dichloride; D000111:Acetylcysteine
vernacular_title: Primenenie atsetiltsisteina v kompleksnom lechenii bol'nykh s ostrym otravleniem 1,2-dikhlorétanom.