Candida and stapedial otosclerosis: histopathological findings.
The stapes of 6 patients with stapedial otosclerosis was found to contain fungus hyphae (Candida) in the sectioned specimens. The footplate of all cases and the head of the stapes in 2 of the cases revealed single or multiple erosion cavities containing numerous thin branching PAS-positive fungus hyphae with swollen terminal endings and scanty blastospores. Osteoclasts were not observed; occasional osteoblasts, blue mantles and otosclerotic foci were seen. Four patients had been treated for several years with antibiotics and corticosteroids for recurrent serous otitis media and 1 patient had had frequent catheterization of the eustachian tube. It may be suggested that the Candida infection was a secondary event induced by a general and/or local immunodepressed condition.
Quaranta
A
A
ENT Department, University of Bari, Italy.
Bartoli
R
R
Resta
L
L
Lozupone
E
E
D000293:Adolescent; D000328:Adult; D002177:Candidiasis / Q000382:microbiology / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D010040:Otosclerosis / Q000382:microbiology / Q000473:pathology*; D013199:Stapes / Q000382:microbiology / Q000473:pathology*