Simplification of superovulation induction in rabbits by means of human menopausal gonadotrophin dissolved in polyvinylpyrrolidone.
Superovulation induction methods in rabbits were simplified by a single subcutaneous (sc) injection of human menopausal gonadotrophin (hMG) dissolved in a 25% solution of polyvinylpyrrolidone (PVP). Superovulatory response was considered satisfactory at sc dose of 60 IU hMG-PVP. Fertilization rates were considered acceptable at doses ranging from 15-90 IU hMG but not at the 120 IU dose. The findings suggest that a single sc injection of 60 IU hMG in 25% PVP will induce a satisfactory superovulatory response in rabbits.
Kanayama
K
K
College of Agriculture and Veterinary Medicine, Nihon University, Fujisawa, Japan.
Endo
T
T
Sakuma
Y
Y
D000818:Animals; D005260:Female; D008596:Menotropins / Q000494:pharmacology*; D011205:Povidone; D011817:Rabbits / Q000502:physiology*; D012996:Solutions; D013480:Superovulation
D012996:Solutions; D008596:Menotropins; D011205:Povidone