Presbycusis: correlations of clinical audiology with morphological changes in the cochlea and the ventral cochlear nucleus.
Five cases of presbycusis are presented. Analysis included audiological tests, cochlear hair cell and ganglion cell counts, assessment of degree of strial atrophy, and ventral cochlear nucleus neuron counts. One case showed a reduction in cochlear nucleus neuron counts without significant cochlear changes, indicating that this pattern of pathological changes is a possible cause of high tone sensorineural deafness.
Armstrong
D
D
Department of Pathology, University of Toronto, Ontario, Canada.
Stoney
P
P
Hawke
M
M
Farkashidy
J
J
D000368:Aged; D001300:Audiometry, Evoked Response; D001301:Audiometry, Pure-Tone; D003051:Cochlea / Q000294:innervation / Q000473:pathology*; D003056:Cochlear Nerve / Q000473:pathology*; D005260:Female; D006198:Hair Cells, Auditory / Q000473:pathology; D006801:Humans; D008297:Male; D009474:Neurons / Q000473:pathology*; D011149:Pons / Q000473:pathology*; D011304:Presbycusis / Q000175:diagnosis / Q000473:pathology*; D013136:Spiral Ganglion / Q000473:pathology; D013316:Stria Vascularis / Q000473:pathology