title: [Discrepant results with immunohistochemical detection TDx/ADx?].
abstract: In the last 2 years we had some problems to confirm the thin-layer results (amphetamines, opiates, benzodiazepines, barbiturates and cocaine) with the immunoassay system TDx/ADx. Between January 1989 and December 1990 we did 883 screenings in urine samples (pre- and postmortal) and had 157 discrepancies (20%). In regard of the high level of discrepancies, we had to test the compatibility of TDx and ADx, their detection limits and compared the results with a second method, thin-layer chromatography. Determining the correlation coefficients to prove our results statistically, we found that both systems, TDx and ADx, work reproducible.
authors: Institut für Rechtsmedizin, Universität Bonn.
authors: M
authors: M
authors: Franke
authors: S
authors: S
authors: Goenechea
authors: F
authors: F
authors: Heinbach
mesh_terms: D002855:Chromatography, Thin Layer; D016231:Fluorescence Polarization Immunoassay; D006801:Humans; D013287:Illicit Drugs / Q000493:pharmacokinetics*; D011180:Postmortem Changes; D011619:Psychotropic Drugs / Q000493:pharmacokinetics*; D015813:Substance Abuse Detection
chemical_list: D013287:Illicit Drugs; D011619:Psychotropic Drugs
vernacular_title: Diskrepante Ergebnisse bei der immunchemischen Nachweismethode TDx/ADx?