Pituitary oncocytoma: three cases report.
Three out of 102 pituitary adenoma patients, including 2 males and one female, had their pituitary tumors diagnosed as "oncocytomas" and underwent transsphenoidal adenomectomy. The tumors were confirmed as "pituitary oncocytomas" by both immunohistochemical staining and electron microscopy. They had poorly developed subcellular organelles and were markedly hyperplastic and pleomorphic, with swollen mitochondria in the cytoplasm and scattered secretory granules along the cell membranes. Postoperative follow-up revealed that visual acuity gradually improved in all the patients, and no tumor recurrence was found. The accurate preoperative diagnosis of pituitary oncocytomas relies on endocrinological, neuroradiological clinical evaluation, and the management of this disease must be surgery with postoperative radiotherapy.
Wang
C J
CJ
Department of Surgery, Kaohsiung Medical College, Taiwan, Republic of China.
Howng
S L
SL
Sun
F F
FF
D000236:Adenoma / Q000473:pathology* / Q000648:ultrastructure; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000473:pathology* / Q000648:ultrastructure