Down syndrome complicated by brain tumors: case report and review of the literature.
This report concerns a 24-year-old male patient with Down syndrome, complicated by a benign but true neoplastic lesion of a differentiated papilloma of the choroid plexus which simultaneously displayed a dysgenetic character. A review of the literature revealed a lack of single case reports of Down syndrome with brain tumors, which may reflect chance occurrence; however, the brain tumors in Down syndrome patients are characterized by their dysontogenetic or dysgenetic character.
Hori
A
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Institute of Neuropathology, Medizinische Hochschule Hannover, Germany.
Walter
G F
GF
Haas
J
J
Becker
H
H
D000328:Adult; D001344:Autopsy; D016545:Choroid Plexus Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D004314:Down Syndrome / Q000150:complications* / Q000473:pathology; D004806:Ependymoma / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008297:Male; D014057:Tomography, X-Ray Computed