title: [The effect of hypoxic hypoxia on the physicochemical and functional properties of hemoglobin in rats].
abstract: The effect of intermittent altitude chamber hypoxia is established to cause an increase in solvability of laboratory rat hemoglobin. Results of immunochemical and fluorescent analysis of the samples of hemoglobin and its component are presented and discussed. They prove that changes in solvability of hemoglobin are determined by the conformational reconstructions of the respiration protein as a result of formation of the complexes with internally erythrocytic metabolites.
authors: V M
authors: VM
authors: Korobov
authors: V I
authors: VI
authors: Nazarenko
authors: M F
authors: MF
authors: Starodub
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology; D000531:Altitude; D000818:Animals; D001273:Atmosphere Exposure Chambers; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004912:Erythrocytes / Q000378:metabolism; D006454:Hemoglobins / Q000737:chemistry* / Q000502:physiology; D000860:Hypoxia / Q000097:blood* / Q000276:immunology / Q000503:physiopathology; D007114:Immunization; D011487:Protein Conformation; D051381:Rats; D017208:Rats, Wistar; D012995:Solubility; D013997:Time Factors
chemical_list: D006454:Hemoglobins
vernacular_title: Vplyv hipoksiĭnoï hipoksiï na fizyko-khemichni ĭ funktsiĭni vlastyvosty hemohl'obinu shchuriv.