Behavioural effects of luteinizing hormone-releasing hormone (LHRH) in rats.
Behavioural effects of intracerebroventricularly-injected (icv) LHRH were studied in female rats. Locomotor and exploratory activities as well as irritability were determined. A pronounced inhibitory effect of 10 micrograms doses of LHRH was found. At 100 micrograms doses of LHRH, barrel behaviour was observed. We conclude that LHRH can modify the activity of central serotonergic receptors in rats.
Mrowiec
J
J
Department of Pharmacology, Medical Faculty in Zabrze, Silesian Medical Academy of Katowice.
Plech
A
A
Rzeszotarska
B
B
Ryszka
F
F
Brus
R
R
Masiukiewicz
E
E
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage / Q000494:pharmacology*; D007276:Injections, Intraventricular; D051381:Rats; D017208:Rats, Wistar
D007987:Gonadotropin-Releasing Hormone