[Protective effect of sho-saiko-to (TJ 9) in experimental liver injury].
Experiments carried out on male mice (ICR) demonstrated a protective effect of premedication with the preparation Sho-Saiko-To (TJ 9, Tsumura and Comp.) against the hepatotoxic effects of CCl4 and T1-acetate, which were manifested by increased peroxidation of lipids and increased depletion of reduced glutathion in liver homogenates.
Eybl
V
V
Ustav farmakologie lékarské fakulty Univerzity Karlovy, Plzen.
Caisová
D
D
Koutenský
J
J
Waitzová
D
D
D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000378:metabolism; D056486:Chemical and Drug Induced Liver Injury; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005978:Glutathione / Q000378:metabolism; D015227:Lipid Peroxidation; D008099:Liver / Q000378:metabolism*; D008107:Liver Diseases / Q000378:metabolism; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D009942:Organometallic Compounds
D004365:Drugs, Chinese Herbal; D009942:Organometallic Compounds; C018142:saiko-keishi-to; D005978:Glutathione; C026995:thallium acetate
K ochrannému úcinku prípravku sho-saiko-to (TJ 9) pri experimentálním poskození jater.