[The urinary metabolites of niacin during the course of pellagra].
The three main metabolites of niacin have been measured in urine of 10 Mozambican women living in refugee camps in Malawi and displaying clinical symptoms of pellagra. This study, in which a control group was included, showed that the ratio 6PYR/N1MN is well correlated to the occurrence of clinical symptoms of niacin deficiency and constitutes a reliable indicator of vitamin PP status in subjects at risk of this deficiency.
Dillon
J C
JC
Laboratoire de Nutrition Humaine, Institut National Agronomique Paris-Grignon, Paris, France.
Malfait
P
P
Demaux
G
G
Foldi-Hopé
C
C
D000293:Adolescent; D000328:Adult; D002851:Chromatography, High Pressure Liquid; D005260:Female; D006801:Humans; D008295:Malawi; D009525:Niacin / Q000378:metabolism* / Q000652:urine; D009536:Niacinamide / Q000378:metabolism; D010383:Pellagra / Q000503:physiopathology / Q000652:urine*; D011728:Pyridones / Q000652:urine; D012036:Refugees
D011728:Pyridones; D009536:Niacinamide; D009525:Niacin
Les métabolites urinaires de la niacine au cours de la pellagre.