[Renal crisis in scleroderma].
A case is described of a 30-year-old woman with scleroderma renal crisis. She presented with classical symptoms: malignant hypertension of sudden onset and rapidly progressive renal failure. End-stage renal failure developed in spite of treatment with angiotensin converting enzyme inhibitors and the patient became dialysis-dependent. Five years later her condition was still stable. She lived in a nursing home, severely disabled but mentally healthy. A renal crisis is one of the most life threatening complications of scleroderma. By immediate treatment with ACE inhibitors, dependence on haemodialysis can be prevented in half the patients.
Fagel
W J
WJ
Academisch Ziekenhuis, afd. Nierziekten, Leiden.
van Es
L A
LA
D058186:Acute Kidney Injury / Q000209:etiology* / Q000628:therapy; D000328:Adult; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006974:Hypertension, Malignant / Q000209:etiology*; D010530:Peritoneal Dialysis; D012595:Scleroderma, Systemic / Q000150:complications*
D000806:Angiotensin-Converting Enzyme Inhibitors
Renale crisis bij sclerodermie.