Mercapturic acid formation from 2-aminopyrazine in rats.
1. The compound 2-aminopyrazine was given by oral gavage to normal rats and their urine collected. 2. A mercapturic acid containing the 2-aminopyrazine moiety was isolated from this urine. This represents the first example of this type of a metabolite from a pyrazine.
Lunn
W H
WH
Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285.
Shadle
J K
JK
D000111:Acetylcysteine / Q000378:metabolism* / Q000652:urine; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D013058:Mass Spectrometry; D011719:Pyrazines / Q000378:metabolism*; D051381:Rats; D011924:Rats, Zucker
D011719:Pyrazines; C079424:2-aminopyrazine; D000111:Acetylcysteine