title: A study of phenotypic variation of Staphylococcus epidermidis using Congo red agar.
abstract: This study examines a series of phenotypic variants of Staphylococcus epidermidis that were generated from a pair of parent variants, isolated from valvular tissue of a patient with prosthetic valve endocarditis. The variants were initially classified by examining their colonial morphology on Congo red agar. In addition to differences in Congo red binding and colonial morphology, they differed in the expression of several surface components and enzymes. Despite these phenotypic differences, all variants had the same restriction endonuclease profile of plasmid DNA. Examination of a collection of clinical isolates demonstrated that phenotypic variation is a common property of S. epidermidis. The ability to express different combinations of surface components and enzymes could contribute to the virulence of S. epidermidis strains by enabling these organisms to colonize a range of diverse environments.
authors: Department of Applied Biology and Biotechnology, Royal Melbourne Institute of Technology, Australia.
authors: M A
authors: MA
authors: Deighton
authors: J
authors: J
authors: Capstick
authors: R
authors: R
authors: Borland
mesh_terms: D000362:Agar; D003224:Congo Red / Q000378:metabolism; D014644:Genetic Variation; D008826:Microbial Sensitivity Tests; D010641:Phenotype; D015995:Prevalence; D013212:Staphylococcus epidermidis / Q000166:cytology / Q000235:genetics* / Q000378:metabolism; D014774:Virulence
chemical_list: D003224:Congo Red; D000362:Agar