title: Changes in the diagnostic parameters during keratoconjunctivitis sicca therapy.
abstract: In 35 patients with mild, moderate and severe keratoconjunctivitis sicca, an association was found between treatment effect, break-up time value and Rose bengal score. Neither of these tests, used separately, was successful as a clinically valuable predictor of treatment effect as the scatter, in score points, was too large. Analysed together, however, as in a partial regression analysis, an adequate prediction is possible, which is clinically of some value.
authors: Department of Ophthalmology, University Hospital Utrecht, The Netherlands.
authors: N
authors: N
authors: Klaassen-Broekema
authors: O P
authors: OP
authors: van Bijsterveld
mesh_terms: D000328:Adult; D000368:Aged; D003228:Conjunctiva / Q000378:metabolism; D003315:Cornea / Q000378:metabolism; D005260:Female; D005782:Gels / Q000627:therapeutic use; D006801:Humans; D007638:Keratoconjunctivitis Sicca / Q000175:diagnosis* / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009113:Muramidase / Q000378:metabolism; D012395:Rose Bengal; D013666:Tears / Q000378:metabolism
chemical_list: D005782:Gels; D012395:Rose Bengal; D009113:Muramidase