[Vertical transmission of HIV: descriptive epidemiology, risk factors and survival (II)].
Up until November 30, 1990, 415 children born to HIV-positive mothers were followed in order to study the vertical transmission rate and the survival of those infected, as well as the associated risk factors. According to CDC criteria, 264 children could be considered definitely classified, with 82 classified as infected (transmission rate: 31.1%) and 182 as sero-negative. The remaining 151 infants were younger than 15 months and classified as PO. Ninety percent of the studied mothers were infected through either the use of intravenous drugs or by sexual intercourse with HIV infected partner. The loss-of-antibody median age was one year. The median for the incubation period was 285 days, with a significant bimodal distribution regarding the child's age at diagnosis. Although the median survival time was longer than the study period, the fatality rate was estimated to be 22.0% and the percentage of children reaching age 4, 27%.
Sánchez Ruiz
E
E
Departament de Sanitat, Generalitat de Catalunya, Barcelona.
Casabona Bárbara
J
J
Fortuny Guasch
C
C
Curell Aguilá
N
N
Martí Gaudes
C
C
D005260:Female; D015658:HIV Infections / Q000151:congenital* / Q000635:transmission; D006679:HIV Seropositivity; D006801:Humans; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D012307:Risk Factors; D015996:Survival Rate
Transmisión vertical del VIH: epidemiología descriptiva, factores de riesgo y supervivencia (II).