Cardiac surgery in HIV-positive intravenous drug addicts: influence of cardiopulmonary bypass on the progression to AIDS.
In the last years the number of HIV-positive patients needing cardiac surgery has greatly increased. Cardiopulmonary bypass is suspected to have a role in the progression of HIV-infection to acquired immunodeficiency syndrome (AIDS). From October 1988 to December 1990, 6 intravenous drug addicts underwent cardiac surgery for infective endocarditis at our Department. Preoperative and postoperative absolute lymphocyte T-helper (CD4) and T-suppressor (CD8) counts did not show a close association between the temporary lymphopenia induced by cardiopulmonary bypass and progression to AIDS.
Lemma
M
M
Department of Thoracic and Cardiovascular Surgery, Luigi Sacco Hospital, Milan, Italy.
Vanelli
P
P
Beretta
L
L
Botta
M
M
Antinori
A
A
Santoli
C
C
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000276:immunology; D000328:Adult; D016516:CD4-CD8 Ratio; D002315:Cardiopulmonary Bypass; D004697:Endocarditis, Bacterial / Q000150:complications / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011182:Postoperative Care; D011300:Preoperative Care; D013203:Staphylococcal Infections / Q000150:complications / Q000601:surgery*; D015819:Substance Abuse, Intravenous