Chromatin diminution in nematode development.
Chromatin diminution in Parascaris and Ascaris represents the classical case of a developmentally programmed genome rearrangement. The process is very specific with respect to ontogenetic timing and chromosomal localization, and involves chromosomal breakage, new telomere formation and DNA degradation. Recent evidence from Ascaris lumbricoides var. suum suggests that chromatin diminution might have a function in gene regulation.
Tobler
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H
Institute of Zoology, University of Fribourg, Switzerland.
Etter
A
A
Müller
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F
D000818:Animals; D001200:Ascaris / Q000196:embryology / Q000235:genetics; D002843:Chromatin / Q000378:metabolism*; D002875:Chromosomes / Q000378:metabolism / Q000648:ultrastructure; D004247:DNA / Q000235:genetics; D004276:DNA, Satellite / Q000235:genetics; D005260:Female; D005786:Gene Expression Regulation; D015321:Gene Rearrangement; D005854:Germ Cells / Q000378:metabolism; D015801:Helminth Proteins; D008297:Male; D009348:Nematoda / Q000196:embryology / Q000235:genetics*; D012269:Ribosomal Proteins / Q000235:genetics
D002843:Chromatin; D004276:DNA, Satellite; D015801:Helminth Proteins; D012269:Ribosomal Proteins; C067677:ALEP-1 protein, Ascaris lumbricoides; D004247:DNA