title: Modification of RBC properties by an autoantibody. Binding to RBC senescent antigen.
abstract: It has been reported that natural antibodies alter aging RBCs, so increasing their vulnerability for removal from the blood stream. Results presented indicate that binding of anti-Gal, a natural antibody, to erythrocytes increases RBC rigidity in terms of microviscosity and deformability. Removal of RBCs from circulation could, at least in part, depend on these alterations.
authors: Université du Québec à Trois-Rivières, Québec, Canada.
authors: R
authors: R
authors: Gareau
authors: G R
authors: GR
authors: Brisson
authors: J
authors: J
authors: Dubé
authors: C
authors: C
authors: Caron
authors: V
authors: V
authors: Longuy
mesh_terms: D000936:Antigen-Antibody Complex; D000941:Antigens / Q000097:blood; D001323:Autoantibodies / Q000097:blood* / Q000302:isolation & purification; D002469:Cell Separation; D002846:Chromatography, Affinity; D002850:Chromatography, Gel; D004905:Erythrocyte Aging / Q000276:immunology*; D004907:Erythrocyte Deformability; D004912:Erythrocytes / Q000166:cytology / Q000276:immunology*; D005454:Fluorescence Polarization; D005690:Galactose / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood / Q000302:isolation & purification
chemical_list: D000936:Antigen-Antibody Complex; D000941:Antigens; D001323:Autoantibodies; D007074:Immunoglobulin G; D005690:Galactose