Structure-activity relationship studies of cocaine: replacement of the C-2 ester group by vinyl argues against H-bonding and provides an esterase-resistant, high-affinity cocaine analogue.
Kozikowski
A P
AP
Neurochemistry Research, Mayo Foundation for Education and Research, Jacksonville, Florida 32224.
Roberti
M
M
Xiang
L
L
Bergmann
J S
JS
Callahan
P M
PM
Cunningham
K A
KA
Johnson
K M
KM
D000818:Animals; D001667:Binding, Competitive; D001921:Brain / Q000187:drug effects / Q000378:metabolism; D003042:Cocaine / Q000031:analogs & derivatives*; D004193:Discrimination Learning; D008454:Mazindol / Q000378:metabolism; D051381:Rats; D013329:Structure-Activity Relationship
D008454:Mazindol; D003042:Cocaine