Blood-cerebrospinal fluid barrier integrity in cerebral infarction.
Using a sensitive isotachophoretic technique total cerebrospinal fluid protein, CSF-serum albumin and CSF-serum IgG ratios as indicators of blood-CSF barrier integrity were determined in 35 cases of ischemic cerebral infarction. Since it proved to be changed in about 57% of these patients, the CSF-serum albumin ratio was found to be the most sensitive parameter in evaluating the blood-CSF barrier disturbances. No clear-cut correlation was found between the age of patients, the clinical course of the disease, different periods after onset of the illness nor the size of the infarction and CSF-blood barrier permeability.
Niebrój-Dobosz
I
I
Department of Neurology, School of Medicine, Warsaw.
Mariam
A G
AG
Lukasiuk
M
M
Rafałowska
J
J
D000368:Aged; D000369:Aged, 80 and over; D001812:Blood-Brain Barrier / Q000502:physiology*; D002544:Cerebral Infarction / Q000097:blood / Q000134:cerebrospinal fluid / Q000503:physiopathology*; D002556:Cerebrospinal Fluid Proteins / Q000502:physiology; D004586:Electrophoresis; D006801:Humans; D008875:Middle Aged
D002556:Cerebrospinal Fluid Proteins