[Antimicrobial activity of AO-128, a novel inhibitor of alpha-D-glucosidase, against anaerobic bacteria].
The in vitro antimicrobial activity of AO-128, an inhibitor of alpha-D-glucosidase, was evaluated against anaerobic bacteria of 45 reference strains (12 genera, 44 species). AO-128 inhibited no strains tested at a concentration of 1,600 micrograms/ml. The results strongly suggested that this compound would not have any influence on the human intestinal microflora, a majority of which is composed of anaerobic bacteria.
Kato
N
N
Institute of Anaerobic Bacteriology, Gifu University School of Medicine.
Watanabe
K
K
Ueno
K
K
D001419:Bacteria / Q000187:drug effects*; D001421:Bacteria, Anaerobic / Q000187:drug effects*; D003511:Cyclohexanols / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D065089:Glycoside Hydrolase Inhibitors
D003511:Cyclohexanols; D065089:Glycoside Hydrolase Inhibitors; C054577:AO 128