[Detection of inhibitors in swine urine with MICUR-BT].
The immersible culture medium MICUR-BT used in human medicine for the detection of antimicrobial substances in the urine was tested for its suitability in pigs. In in-vitro tests, 15 pure antibiotic substances, 2 pure substance mixtures as well as 5 veterinary injection preparations with no direct antimicrobial effect were checked. The agar perforation test was used as a reference procedure. In a total of 65 pigs the detectability of 9 pure antibiotic and chemotherapeutic agents, 2 pure substance mixtures as well as 5 veterinary drugs with no direct antimicrobial effect was tested after oral or parenteral application. In the in-vivo tests the MICUR-BT test turned out to be more reliable than the agar perforation test. In 76.9% of the untreated pigs below 30 kg b.w. the MICUR-BT-test showed an antimicrobial effect. Such effects were reduced by 38.3% in the reference procedure.
Heinritzi
K
K
II. Medizinischen Tierklinik Ludwig-Maximilians-Universität München.
Hartel
I
I
Bollwahn
W
W
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000652:urine*; D001412:Bacillus subtilis / Q000187:drug effects; D003470:Culture Media; D005260:Female; D013552:Swine / Q000652:urine*
D000900:Anti-Bacterial Agents; D003470:Culture Media
Untersuchungen zum Hemmstoffnachweis im Schweineharn mit MICUR-BT.