EoL-1, a human eosinophilic cell line.
EoL-1 cells, a recently established human eosinophilic leukemia cell line, have cytological features of myeloblasts under normal culture conditions, and differentiate not only phenotypically but also functionally into eosinophils by a number of stimuli. EoL-1 cells are particularly useful for analyzing leukemic cell differentiation and the properties of malignant eosinophils. EoL-1 cells are also a useful in vitro model for studying human eosinophil functions and their regulation.
Mayumi
M
M
Department of Pediatrics, Kyoto University Hospital, Japan.
D015815:Cell Adhesion Molecules / Q000502:physiology; D002454:Cell Differentiation; D004804:Eosinophils / Q000166:cytology / Q000473:pathology* / Q000502:physiology*; D006801:Humans; D015472:Leukemia, Eosinophilic, Acute / Q000097:blood* / Q000473:pathology*; D011961:Receptors, Fc / Q000502:physiology; D012016:Reference Values; D014407:Tumor Cells, Cultured
D015815:Cell Adhesion Molecules; D011961:Receptors, Fc