Reversal of neurological deficit with naloxone: an additional report.
We report the repeated improvement in neurological function following naloxone administration in a patient who developed acute hemiplegia after an intracranial neurological procedure. The mechanisms responsible for the neurological deficit and for its reversal by naloxone are discussed. A review of the literature suggests that the beneficial effect of naloxone can result from an improvement in haemodynamic status or from metabolic effects that could be favorable during cerebral ischaemia.
Hans
P
P
University Department of Anesthesiology, CHR de la Citadelle, Liège, Belgium.
Brichant
J F
JF
Longerstay
E
E
Damas
F
F
Remacle
J M
JM
D016080:Arachnoid Cysts / Q000601:surgery*; D005260:Female; D006429:Hemiplegia / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008875:Middle Aged; D009270:Naloxone / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology; D017409:Sufentanil / Q000009:adverse effects; D014057:Tomography, X-Ray Computed
D009270:Naloxone; D017409:Sufentanil