title: Juvenile colloid milium: clinical, histological and ultrastructural features.
abstract: We report the clinical, histological and ultrastructural features of juvenile colloid milium affecting a brother and sister. In this rare condition, translucent papules develop on sun-exposed areas of skin, with onset in childhood. Histologically and ultrastructurally, the papules consist of amyloid-like material derived from epidermal keratonocytes. A review of the literature suggests a possible genetic abnormality that leads to sun-induced degeneration of keratinocytes.
authors: St. John's Dermatology Centre, St. Thomas' Hospital, London, England.
authors: S E
authors: SE
authors: Handfield-Jones
authors: D J
authors: DJ
authors: Atherton
authors: M M
authors: MM
authors: Black
authors: K
authors: K
authors: Hashimoto
authors: P H
authors: PH
authors: McKee
mesh_terms: D000293:Adolescent; D000682:Amyloid / Q000032:analysis; D002648:Child; D003102:Colloids / Q000032:analysis*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D015603:Keratinocytes / Q000737:chemistry / Q000473:pathology / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D012867:Skin / Q000737:chemistry* / Q000473:pathology / Q000648:ultrastructure; D012871:Skin Diseases / Q000209:etiology / Q000235:genetics / Q000473:pathology*; D013472:Sunlight
chemical_list: D000682:Amyloid; D003102:Colloids