title: Amino acid structure and "difficult sequences" in solid phase peptide synthesis.
abstract: Deprotection peak profiles have been determined as a measure of internal aggregation during Fmoc-polyamide continuous flow solid phase synthesis. The results have been correlated with amino-acid structure and discussed in terms of minimising aggregation during synthesis.
authors: MRC Laboratory of Molecular Biology, Cambridge, UK.
authors: J
authors: J
authors: Bedford
authors: C
authors: C
authors: Hyde
authors: T
authors: T
authors: Johnson
authors: W
authors: W
authors: Jun
authors: D
authors: D
authors: Owen
authors: M
authors: M
authors: Quibell
authors: R C
authors: RC
authors: Sheppard
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000737:chemistry*; D008969:Molecular Sequence Data; D010455:Peptides / Q000138:chemical synthesis*
chemical_list: D000596:Amino Acids; D010455:Peptides