Effects of vasoactive intestinal polypeptide on isolated rat urinary bladder smooth muscle.
The effect of vasoactive intestinal polypeptide (VIP) on the contractile activity of the urinary bladder was investigated in the rat. VIP caused a weak contraction and a small potentiation of carbachol- and acetylcholine-induced contractions. The present results may provide the evidence that VIP could be a modulator in the urinary bladder.
Erol
K
K
Department of Pharmacology, University of Anadolu, School of Medicine, Eskişehir, Turkey.
Ulak
G
G
Dönmez
T
T
Cingi
M I
MI
Alpan
R S
RS
Ozdemir
M
M
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D002217:Carbachol / Q000494:pharmacology; D066298:In Vitro Techniques; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects*; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D001743:Urinary Bladder / Q000187:drug effects / Q000502:physiology*; D014660:Vasoactive Intestinal Peptide / Q000494:pharmacology* / Q000502:physiology
D014660:Vasoactive Intestinal Peptide; D002217:Carbachol; D000109:Acetylcholine