Production of bellenamine and new metabolites in a synthetic medium.
A streptomyces antibiotic, bellenamine has been produced in a simple synthetic medium consisting of D-galactose, dextrin, ammonium sulfate and calcium carbonate. Three new minor metabolites, N-(aminomethyl)succinamic acid, 1'-N-acetylbellenamine and D-beta-lysinamide have been isolated from the synthetic medium culture. They showed no antibiotic activity.
Ikeda
Y
Y
Institute of Microbial Chemistry, Tokyo, Japan.
Gomi
S
S
Hamada
M
M
Kondo
S
S
Takeuchi
T
T
D000645:Ammonium Sulfate; D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000378:metabolism; D002119:Calcium Carbonate; D003470:Culture Media; D003912:Dextrins; D005690:Galactose; D008239:Lysine / Q000031:analogs & derivatives / Q000096:biosynthesis / Q000737:chemistry / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D013302:Streptomyces / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D003470:Culture Media; D003912:Dextrins; C048662:beta-lysylmethanediamine; D002119:Calcium Carbonate; D008239:Lysine; D000645:Ammonium Sulfate; D005690:Galactose