title: A six-center international study of treatment outcome in patients with clefts of the lip and palate: Part 1. Principles and study design.
abstract: This article describes the design of an intercenter comparative study of treatment outcome in the treatment of children with a unilateral complete cleft of the lip and palate. The rationale and aims of this study are defined and treatment schemes of the participating centers are described. The findings are presented in a series of three papers (Parts 2, 3, and 4) dealing with the comparison of craniofacial form, dental arch relationships, and nasolabial appearance. In Part 5, conclusions and general recommendations regarding future research are discussed.
authors: Division of Dentistry, Childrens Hospital of Los Angeles, CA 90027.
authors: W C
authors: WC
authors: Shaw
authors: C
authors: C
authors: Asher-McDade
authors: V
authors: V
authors: Brattström
authors: E
authors: E
authors: Dahl
authors: J
authors: J
authors: McWilliam
authors: K
authors: K
authors: Mølsted
authors: D A
authors: DA
authors: Plint
authors: B
authors: B
authors: Prahl-Andersen
authors: G
authors: G
authors: Semb
authors: R P
authors: RP
authors: The
mesh_terms: D002648:Child; D002675:Child, Preschool; D002971:Cleft Lip / Q000601:surgery* / Q000628:therapy; D002972:Cleft Palate / Q000601:surgery* / Q000628:therapy; D004282:Documentation; D005060:Europe; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D015337:Multicenter Studies as Topic; D017063:Outcome Assessment, Health Care; D015203:Reproducibility of Results; D012107:Research Design; D012189:Retrospective Studies; D016896:Treatment Outcome; D016526:Workload