title: Syntheses and activities of N-substituted derivatives of siastatin B.
abstract: N-Substituted derivatives of siastatin B have been obtained by a chemical modification. Some derivatives showed potent inhibitory activities against Streptococcus sp. and Clostridium perfringens neuraminidases.
authors: Institute of Microbial Chemistry, Tokyo, Japan.
authors: T
authors: T
authors: Kudo
authors: Y
authors: Y
authors: Nishimura
authors: S
authors: S
authors: Kondo
authors: T
authors: T
authors: Takeuchi
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D003016:Clostridium perfringens / Q000187:drug effects / Q000201:enzymology; D009682:Magnetic Resonance Spectroscopy; D009439:Neuraminidase / Q000037:antagonists & inhibitors*; D010880:Piperidines / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D013291:Streptococcus / Q000187:drug effects / Q000201:enzymology; D013329:Structure-Activity Relationship
chemical_list: D000900:Anti-Bacterial Agents; D010880:Piperidines; C078939:3,4-didehydro-4-deoxysiastatin B; C078940:4-deoxysiastatin B; C011353:siastatin; D009439:Neuraminidase