title: Correlation in ages at death from familial ovarian cancer among sisters.
abstract: The analysis of pedigrees taken from 97 of 1466 women attending a screening clinic for early familial ovarian cancer showed that there was a strong correlation in the ages at death from the disease among sisters (r = 0.68, confidence limits 0.51-0.82, P < 0.001), but not between mothers and daughters. This information can be used to help counsel women who are considering the appropriate time for more intensive screening or prophylactic oophorectomy.
authors: Department of Clinical Genetics, Royal Free Hospital School of Medicine, London, United Kingdom.
authors: R S
authors: RS
authors: Houlston
authors: J
authors: J
authors: Hampson
authors: W P
authors: WP
authors: Collins
authors: M I
authors: MI
authors: Whitehead
authors: S
authors: S
authors: Campbell
authors: J
authors: J
authors: Slack
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000235:genetics* / Q000401:mortality*; D010375:Pedigree