title: [Myopathy associated with infection by the human immunodeficiency virus type-1 (HIV-1)].
abstract: We present a case of an active homosexual patient who was a paid donor of plasma and presented myopathy associated to infection by the human immunodeficiency virus type 1 (HIV-1). In the ultrastructural study of the muscular biopsy, we stress the formation of central intermyofibrillary "minocores", as well as the presence of nuclear extrusions in which the core is surrounded by mitochondrial accumulations. We review the clinical, histological and ultrastructural characteristics used to identity this pathology against the group of myopathies induced by zidovudine, as well as the several empirical therapies currently recommended.
authors: Servicio de Medicina Interna, Hospital Clínico Universitario, Valencia.
authors: F
authors: F
authors: Gabriel Botella
authors: E
authors: E
authors: Rosello Sastre
authors: M
authors: M
authors: Labios Gómez
authors: C
authors: C
authors: Carda Batalla
authors: J V
authors: JV
authors: Balaguer Martínez
authors: M
authors: M
authors: Arnal Babiloni
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000175:diagnosis / Q000473:pathology; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D001706:Biopsy; D015483:HIV Antibodies / Q000097:blood; D015497:HIV-1; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000648:ultrastructure; D009135:Muscular Diseases / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D011020:Pneumonia, Pneumocystis / Q000150:complications / Q000175:diagnosis / Q000473:pathology
chemical_list: D015483:HIV Antibodies
vernacular_title: Miopatía asociada a la infección por el virus de la inmunodeficiencia humana tipo-1 (VIH-1).