Monocytoid B-cell lymphoma of the prostate.
A case of a primary malignant non-Hodgkin's lymphoma of the prostate, with the histological and immunohistochemical features of monocytoid B-cell lymphoma, is presented. The tumor histology was identical to that described in the forms of node-based monocytoid B-cell lymphoma being composed of a dense, monomorphous lymphoid infiltrate with ovoid nuclei and rather abundant, pale cytoplasm. Phenotypic analysis revealed high expression of B markers 4KB5 and L26, and negativity for T-associated antigens. This unusual localization broadens the spectrum of extra-nodal sites of monocytoid B-cell lymphoma.
Franco
V
V
Istituto di Anatomia Patologica, dell'Università di Palermo.
Florena
A M
AM
Quintini
G
G
Ingargiola
G B
GB
D000368:Aged; D000911:Antibodies, Monoclonal / Q000276:immunology; D000944:Antigens, Differentiation, B-Lymphocyte / Q000032:analysis*; D014408:Biomarkers, Tumor / Q000032:analysis*; D006801:Humans; D016130:Immunophenotyping; D016393:Lymphoma, B-Cell / Q000737:chemistry / Q000473:pathology*; D008297:Male; D011471:Prostatic Neoplasms / Q000737:chemistry / Q000473:pathology*
D000911:Antibodies, Monoclonal; D000944:Antigens, Differentiation, B-Lymphocyte; D014408:Biomarkers, Tumor