title: Excimer laser refractive keratectomy for high myopia. 6-month follow-up of patients treated bilaterally.
abstract: Both eyes of twenty patients were treated for myopia with refractive keratectomy using an excimer laser (193 nm), and followed for six months. The 40 eyes were divided into Group I (22 eyes) with an attempted refraction change of 5-8 diopters; and Group I (18 eyes) with 9-12 diopters of attempted refraction change. In Group I the corrected visual acuity improved or was unchanged in 16/22 eyes. Two eyes with high preoperative corrected visual acuity had experienced a significant loss in corrected visual acuity after 6 months. In Group II, the corrected visual acuity decreased in 10/18 eyes, in 4 eyes significantly. Among the 40 eyes, 39 had a refraction change less than intended after 6 months. Overcorrection was seen in only 1 eye. In Group I, 20/22 eyes were corrected up to 2.5 diopters less than attempted. In Group II, 9/18 eyes were more than 2.5 diopters from the attempted correction. All eyes developed subepithelial opacification ('haze'), which, in spite of steroid treatment, was still present after 6 months. The haze was more severe in eyes treated with 9-12 diopters of attempted refraction change. The achieved refraction change in the two eyes of the same patient was found to be correlated, possibly due to an individual factor in corneal wound healing.
authors: Department of Ophthalmology, Arhus University Hospital, Denmark.
authors: N
authors: N
authors: Ehlers
authors: J O
authors: JO
authors: Hjortdal
mesh_terms: D000293:Adolescent; D000328:Adult; D002452:Cell Count; D003315:Cornea / Q000473:pathology / Q000601:surgery*; D003318:Corneal Opacity / Q000209:etiology / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000601:surgery*; D012029:Refraction, Ocular; D014786:Vision Disorders / Q000209:etiology; D014792:Visual Acuity