Endocrine disorders in pregnancy.
Disorders of the pituitary gland such as diabetes insipidus, pituitary adenomas, and hyperprolactinemia, disorders of the thyroid gland such as Graves' disease and hypothyroidism, and diseases of the adrenal gland such as adrenocortical insufficiency and Cushing's syndrome can complicate pregnancy. The goals of this article were to provide a basic scientific understanding of the normal function of these endocrine glands, their pregnancy-related changes, and suggestions for diagnosis and treatment of maternal and fetal endocrine disorders during pregnancy. Antenatal recognition and appropriate management of the disorders that especially affect the fetus (i.e., maternal Graves' disease, fetal hypothyroidism, and congenital adrenal hyperplasia) is essential in order to prevent fetal and neonatal morbidity and mortality.
Sipes
S L
SL
Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, Iowa City.
Malee
M P
MP
D000307:Adrenal Gland Diseases; D004700:Endocrine System Diseases / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans; D010900:Pituitary Diseases; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000628:therapy; D013959:Thyroid Diseases