The development of a microwave fluid-bed processor. I. Construction and qualification of a prototype laboratory unit.
The static bed- and planetary-type microwave dryers currently available to process pharmaceutical materials are not designed to use hot-air fluidization for the purpose of maximizing microwave energy inputs and particle drying. To take advantage of the benefits offered by fluidization, a 1-kg Uni-Gatt laboratory fluid bed processor was modified to support microwave-assisted fluid bed drying of several representative pharmaceutical granulations. The construction, design features, and validation of this new microwave fluid bed processor are presented.
Doelling
M K
MK
St. John's University College of Pharmacy and Allied Health Professions, Jamaica, New York 11439.
Jones
D M
DM
Smith
R A
RA
Nash
R A
RA
D002138:Calibration; D003890:Desiccation; D004339:Drug Compounding / Q000295:instrumentation*; D008872:Microwaves