title: Determination of the relative configuration of 5,6,7,8-tetrahydromethanopterin by two-dimensional NMR spectroscopy.
abstract: The relative configuration of the pterin moiety of 5,6,7,8-tetrahydromethanopterin 1, a coenzyme isolated from methanogenic archaea, has been determined by two-dimensional NMR spectroscopy of N5,N10-methenyl-5,6,7,8-tetrahydromethanopterin 2 to be rel-(6R; 7S; 11R). The complete proton resonance assignment of the pterin moiety of N5,N10-methylene-5,6,7,8-tetrahydromethanopterin 3 is described including the relative stereospecific assignment of the C(14a) methylene protons.
authors: Institute for Organic Chemistry, University of Frankfurt, Germany.
authors: J
authors: J
authors: Schleucher
authors: B
authors: B
authors: Schwörer
authors: C
authors: C
authors: Zirngibl
authors: U
authors: U
authors: Koch
authors: W
authors: W
authors: Weber
authors: E
authors: E
authors: Egert
authors: R K
authors: RK
authors: Thauer
authors: C
authors: C
authors: Griesinger
mesh_terms: D009682:Magnetic Resonance Spectroscopy; D017014:Methanobacterium / Q000737:chemistry; D015394:Molecular Structure; D011622:Pterins / Q000737:chemistry*
chemical_list: D011622:Pterins; C042416:5,6,7,8-tetrahydromethanopterin