Allergic rhinoconjunctivitis: diagnostic and clinical assessment.
In allergic rhinoconjunctivitis not only the nasal mucosa but also the conjunctiva and, in severe cases, the cornea are affected by reactive phenomena. This pathological process is often encountered in clinical practice, its incidence ranging from 10% to 30% of the whole population, as reported by many authors. Up to now, the pathogenetic mechanisms of allergic reactivity are not completely understood. In our opinion this is due to insufficient standardization of the diagnostic procedures; even the clinical picture of such a pathological process seems to be insufficient, especially with regard to the analogies between the nasal and conjunctival pathologies. To a great extent this depends on the different clinical pictures both in otorhinolaryngology and ophthalmology. Our study has been carried out on 98 patients suffering from rhinoconjunctivitis, and presents an accurate documentation with regard to the existence of analogies in reactivity at the immunoallergic level, in both the nose and conjunctiva. These are evident when we refer not only to specific routine allergological tests but, mainly, to local examinations. The evaluation of the selected data enables us to formulate a single classification of allergic rhinoconjunctivitis, taking into account the common reactive phenomena.
Salzano
F A
FA
Dept. of Otorhinolaryngology, University of Naples, Italy.
d'Angelo
L
L
Motta
S
S
del Prete
A
A
Gentile
M
M
Motta
G
G
D000328:Adult; D000485:Allergens; D003228:Conjunctiva / Q000382:microbiology; D003233:Conjunctivitis, Allergic / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D015994:Incidence; D009297:Nasal Mucosa / Q000382:microbiology; D009299:Nasal Provocation Tests; D011852:Radioallergosorbent Test; D012221:Rhinitis, Allergic, Perennial / Q000175:diagnosis* / Q000453:epidemiology; D006255:Rhinitis, Allergic, Seasonal / Q000175:diagnosis* / Q000453:epidemiology; D012882:Skin Tests
D000485:Allergens; D007073:Immunoglobulin E