title: Safety and efficacy of percutaneous injection of polyurethane elastomer (MPU) plugs for vas occlusion in man.
abstract: This report describes the safety and efficacy of the procedure for percutaneous injection of medical-grade polyurethane elastomer (MPU) to form plugs in the vas deferens. The injection of 0.16-0.22 ml MPU in 53 men resulted in occlusion and azoospermia in 85% of the men after 12 months; 96% achieved azoospermia by 2 years. The success rate of the method and the rate of sperm suppression to azoospermia depended on the shapes of the plugs; this was determined by palpation after insertion. There were few complications and the results are discussed in terms of the reversibility potential of this method.
authors: National Research Institute for Family Planning, Beijing, China.
authors: Z W
authors: ZW
authors: Chen
authors: Y Q
authors: YQ
authors: Gu
authors: X W
authors: XW
authors: Liang
authors: Z G
authors: ZG
authors: Wu
authors: E J
authors: EJ
authors: Yin
authors: Li-Hong
mesh_terms: D000328:Adult; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections; D008297:Male; D011140:Polyurethanes / Q000008:administration & dosage / Q000009:adverse effects*; D019736:Prostheses and Implants / Q000009:adverse effects; D012449:Safety; D013245:Sterilization, Reproductive / Q000009:adverse effects*; D014649:Vas Deferens
chemical_list: D011140:Polyurethanes