[Positron emission tomography of C-11-labelled selegiline].
The combination of C-11-labelled Selegiline with PET gives the possibility of a non-invasive method for the determination of the distribution, activity and turnover of MAO-B enzyme and all the enzyme-related changes in the brain as well as for the early detection of Parkinson's disease.
Szatmári
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Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt., Budapest.
Hermecz
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D000818:Animals; D001921:Brain / Q000201:enzymology; D002250:Carbon Radioisotopes; D008297:Male; D051379:Mice; D008995:Monoamine Oxidase / Q000378:metabolism; D010302:Parkinson Disease, Secondary / Q000000981:diagnostic imaging / Q000201:enzymology; D012642:Selegiline; D014055:Tomography, Emission-Computed
D002250:Carbon Radioisotopes; D012642:Selegiline; D008995:Monoamine Oxidase
Vizsgálatok pozitron emissziós tomográfia és 11C jelzett selegilin alkalmazásával.