title: Laparoscopic nephrectomy in a porcine model.
abstract: Laparoscopic nephrectomy was performed in 15 male pigs, the procedure was successful in 14. Extraction of the intact kidney through a 5-cm lower abdomen incision was done in 7 animals; complete destruction and evacuation of the kidney was accomplished by a round-knife suction device through a 1-cm port in another 7 pigs. Grossly, the specimen consisted of sausage-like tubular renal tissue and a small amount of tissue debris. Pathology revealed that the glomerular and tubular structures were well preserved, no interstitial hematoma could be found. Four ports were usually used, one 1-cm umbilical camera port, one 0.5-cm port for ureter traction, and two 1-cm working ports along the midclavicular line. All the pigs recovered uneventfully. The average operation time was 3 h 20 min. The application of endo-GIA (United States Surgical Corporation) for renal hilum reduced the operative time to 2 h 20 min. Complications included renal vein tear during endoclip application and cutting in the first case, mild subcutaneous emphysema in 2 cases. This first pig received exploratory laparotomy for the repair and ligation of the renal vein. No more major complications occurred with increasing experience. From this porcine experiment, we conclude that the combination of laparoscopy, a tissue destroyer and an endobag for the entrapment of kidney seem to be a promising technique for clinical nephrectomy.
authors: Department of Surgery, National Yang-Ming Medical College, Veterans General Hospital-Taipei, Taiwan, ROC.
authors: A W
authors: AW
authors: Chiu
authors: M T
authors: MT
authors: Chen
authors: W J
authors: WJ
authors: Huang
authors: S T
authors: ST
authors: Young
authors: C
authors: C
authors: Cheng
authors: S W
authors: SW
authors: Huang
authors: C L
authors: CL
authors: Chu
authors: L S
authors: LS
authors: Chang
mesh_terms: D000818:Animals; D010535:Laparoscopy; D008297:Male; D009392:Nephrectomy / Q000295:instrumentation / Q000379:methods*; D011183:Postoperative Complications; D013523:Surgical Equipment; D013552:Swine; D014572:Urology / Q000295:instrumentation