title: Brown bowel syndrome: a late complication of intestinal atresia.
abstract: Two children, aged 11 years, who originally had jejunal atresia corrected in the neonatal period, developed massive dilatation of the proximal small intestine. This resulted in circular muscular hypertrophy with lipofuscin deposits giving the typical appearance of "brown bowel." The condition was associated with malnutrition and vitamin E deficiency. Because of relatively short bowel, the condition was treated by limited resection and extensive tapering of the dilated segment, end-to-end reanastomosis, vitamin E supplementation, and intensive nutritional support.
authors: Hospital for Sick Children, London, England.
authors: H C
authors: HC
authors: Ward
authors: J
authors: J
authors: Leake
authors: P J
authors: PJ
authors: Milla
authors: L
authors: L
authors: Spitz
mesh_terms: D002648:Child; D015362:Child Nutrition Disorders / Q000209:etiology; D004108:Dilatation, Pathologic; D005260:Female; D006801:Humans; D007409:Intestinal Atresia / Q000150:complications* / Q000601:surgery; D007579:Jejunal Diseases / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D007583:Jejunum / Q000002:abnormalities* / Q000378:metabolism / Q000473:pathology; D008062:Lipofuscin / Q000378:metabolism; D008297:Male; D013997:Time Factors
chemical_list: D008062:Lipofuscin