Caloric and nitrogen balances as predictors of nutritional outcome in patients with burns.
Measurement of energy expenditure with indirect calorimetry allows determination of caloric balance. The present study was done to determine the predictive value of caloric and nitrogen balances for nutritional outcome. Energy expenditure was obtained weekly and interpolated between measurements for daily caloric balance. Nitrogen balance was obtained weekly. Because nitrogen output fluctuated, interpolation of daily values was not possible. Nutritional outcome was defined by whether body weight was lost or maintained and by levels of visceral proteins (albumin, prealbumin, and transferrin). The study group included 12 patients with 7% to 82.5% total body surface area burns. Eleven patients survived their burn injuries, and one died of congestive heart failure at 38 days, after her burn wounds had healed. Nine patients had good nutritional outcomes (group 1) and three had poor nutritional outcomes (group 2) (including the one who died). Nitrogen balance was 1.3 +/- 1.0 gm/day in group 1 and 4.5 +/- 1.7 gm/day in group 2 (mean +/- SEM; p > 0.10). Caloric balance was 515 +/- 130 kcal/day in group 1 and -667 +/- 140 in group 2 (p < 0.001). Caloric balance was significantly different between the two groups, whereas nitrogen balance was not. Caloric intake correlated positively with nitrogen intake (r = 0.92). Nitrogen intake was 16% of total caloric intake. Nitrogen intake from blood products was appreciable and averaged 15% of total nitrogen intake (range, 0% to 47%); 11.3 +/- 1.6 gm/day in group 1 and 14.8 +/- 3 gm/day in group 2 (p > 0.10).(ABSTRACT TRUNCATED AT 250 WORDS)
Mancusi-Ungaro
H R
HR
Department of Surgery, University of New Mexico, Albuquerque.
Van Way
C W
CW
McCool
C
C
D002056:Burns / Q000378:metabolism / Q000401:mortality / Q000628:therapy*; D002153:Calorimetry, Indirect; D002149:Energy Intake; D004734:Energy Metabolism; D004750:Enteral Nutrition; D006801:Humans; D009584:Nitrogen / Q000378:metabolism; D015596:Nutrition Assessment; D009752:Nutritional Status; D010288:Parenteral Nutrition; D011237:Predictive Value of Tests; D012044:Regression Analysis; D012189:Retrospective Studies; D015431:Weight Loss
D009584:Nitrogen