title: Coronary artery spasm and acute myocardial infarction in naproxen-associated anaphylactic reaction.
abstract: We present the case of a 43-year-old man who suffered an acute myocardial infarction after oral administration of 250 mg of naproxen, prescribed as antiinflammatory-analgesic agent after tooth extraction. Both intradermal skin test and human basophil degranulation test were positive to naproxen. These findings suggest a naproxen-associated anaphylactic reaction with concomitant coronary artery spasm and posteroinferior infarction, a clinical event previously not reported with the use of this drug.
authors: Allergy Unit, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.
authors: A
authors: A
authors: Cisteró
authors: S
authors: S
authors: Urías
authors: J
authors: J
authors: Guindo
authors: R
authors: R
authors: Lleonart
authors: M
authors: M
authors: Garcia-Moll
authors: A
authors: A
authors: Geli
authors: A
authors: A
authors: Bayés de Luna
mesh_terms: D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced* / Q000150:complications; D003329:Coronary Vasospasm / Q000209:etiology*; D004342:Drug Hypersensitivity / Q000209:etiology*; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000209:etiology*; D009288:Naproxen / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D009288:Naproxen