title: Age-related changes in occipital alpha rhythm of adults with Down syndrome.
abstract: A power spectral analysis was performed on occipital EEGs recorded from 36 Down Syndrome (DS) subjects aged 15 to 54 and compared with two control groups; 47 healthy volunteers (Control) and 42 mentally retarded people without DS (MR). The frequencies of occipital alpha rhythms of DS showed a significant inverse correlation with chronological age, while Control and MR did not. The average frequencies of DS were significantly low even in the youngest age-group in comparison with those of Control, and also decreased in the age-groups of 35 and older compared with MR. It was considered that a slowing of alpha rhythm was a manifestation of premature aging that occurred in the underdeveloped brains of DS.
authors: Department of Neuropsychiatry, Wakayama Medical College, Japan.
authors: Y
authors: Y
authors: Ono
authors: H
authors: H
authors: Yoshida
authors: Y
authors: Y
authors: Momotani
authors: F
authors: F
authors: Yoshimasu
authors: Y
authors: Y
authors: Higashi
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000513:Alpha Rhythm; D000544:Alzheimer Disease / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology; D004314:Down Syndrome / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D004569:Electroencephalography / Q000295:instrumentation; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology; D008297:Male; D008875:Middle Aged; D009778:Occipital Lobe / Q000503:physiopathology*; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation