[Phagocytic activity of the central macrophage of erythroblastic islet in experimental inhibition and stimulation of erythropoiesis].
Phagocytic activity of the erythroblastic island central macrophage (EICM) was studied under normal conditions and in experimental inhibition and stimulation of erythropoiesis. Specific phagocytic activity (SPA) was estimated by the amount of latex particles absorbed by 1 EICM during 30-min incubation on plastic Petri dishes. SPA of CM in all the animals (no matter what experimental model was chosen) depended on EI affiliation to a certain class, with the maximum activity in EICM of the III class. SPA in EICM of the II-III classes in polycythemia animals was low. Blood loss significantly increased SPA in EICM of the II-IV classes of maturity. EICM of the I class showed a lower SPA that was, probably, due to the involvement of immature monocytes into EI organization.
Zakharov
Iu M
IuM
Varypaeva
L P
LP
D000818:Animals; D001803:Blood Transfusion; D001815:Bloodletting; D004900:Erythroblasts / Q000166:cytology / Q000276:immunology*; D004906:Erythrocyte Count; D017707:Erythrocyte Transfusion; D004920:Erythropoiesis / Q000276:immunology / Q000502:physiology*; D005260:Female; D066298:In Vitro Techniques; D007840:Latex; D008264:Macrophages / Q000276:immunology*; D008863:Microspheres; D008954:Models, Biological; D010587:Phagocytosis / Q000276:immunology*; D051381:Rats
D007840:Latex
Fagotsitarnaia aktivnost' tsentral'nogo makrofaga éritro- blasticheskogo ostrovka pri éksperimental'nom tormozhenii i stimuliatsii éritropoéza.