[The effect of malonate on lipid biosynthesis in the liver].
Malonate regulates the liver metabolism and promotes stimulation of the fatty acids synthesis and pyruvate oxidation inhibition. The latter is particularly significant in regulation of aerobic processes and responsible for antihypoxic action of malonate.
Davydov
V V
VV
Skorik
G V
GV
Krisanova
N V
NV
D000818:Animals; D002250:Carbon Radioisotopes; D005260:Female; D066298:In Vitro Techniques; D008055:Lipids / Q000096:biosynthesis*; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008314:Malonates / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D014316:Tritium
D002250:Carbon Radioisotopes; D008055:Lipids; D008314:Malonates; D014316:Tritium; C030290:malonic acid
Vliianie malonata na biosintez lipidov v pecheni.