Hemostatic activity of the bovine parotid gland glycoconjugates.
The bovine parotid gland was studied by means of biochemical analyses and the glycoconjugates extracted were used to investigate the activity on the human hemostatic system. Thromboelastography was unable to reveal anticoagulant properties. Conversely, the Thrombin Time (TT) was prolonged in a statistically significant way and with dose-coupling response. Reptilase Time (RT) was affected by the highest concentration of extract suggesting that the bovine parotid glycoconjugates alter the fibrinogen polymerization.
Menghi
G
G
Dipartimento di Biologia M.C.A. Università di Camerino, Italy.
Piciotti
D
D
Ravaglia
F
F
D000818:Animals; D012103:Batroxobin / Q000378:metabolism; D001777:Blood Coagulation / Q000502:physiology*; D002417:Cattle; D005340:Fibrinogen / Q000378:metabolism; D006001:Glycoconjugates / Q000502:physiology*; D010306:Parotid Gland / Q000502:physiology*; D013916:Thrombelastography; D013918:Thrombin Time
D006001:Glycoconjugates; D005340:Fibrinogen; D012103:Batroxobin