title: Use of polymerase chain reaction nad denaturing gradient gel electrophoresis to identify polymorphisms in three exons of dopamine D2 receptor gene in schizophrenic and delusional patients.
abstract: The dopamine D2 receptor gene is a candidate gene for schizophrenia. We screened three exons of this gene for mutations in a large sample of schizophrenics, delusional patients and healthy controls. No structural changes were found, thus suggesting that psychopathology is not related to DNA alterations in the DRD2 gene.
authors: Istituto di Ricovero e Cura a Carattere Scientifico H. San Raffaele, Università degli Studi di Milano, Italia.
authors: M
authors: M
authors: Catalano
authors: M
authors: M
authors: Nobile
authors: E
authors: E
authors: Novelli
authors: E
authors: E
authors: Smeraldi
mesh_terms: D000328:Adult; D000483:Alleles; D003702:Delusions / Q000235:genetics* / Q000523:psychology; D004586:Electrophoresis; D005091:Exons / Q000235:genetics*; D005260:Female; D005787:Gene Frequency / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009154:Mutation / Q000235:genetics; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic / Q000235:genetics*; D017448:Receptors, Dopamine D2 / Q000235:genetics*; D012559:Schizophrenia / Q000235:genetics*; D012565:Schizophrenic Psychology; D015398:Signal Transduction / Q000235:genetics
chemical_list: D017448:Receptors, Dopamine D2