title: Recent advances in the pathogenesis of atopic dermatitis.
abstract: Atopic dermatitis (AD) is an inflammatory skin disorder affecting 5%-10% of children. Although basic mechanisms remain largely speculative, recent studies on the pathogenesis have elucidated new insights, pointing to the importance of food and inhalant allergens. The pathogenesis of AD can be more easily explained by the model of late skin reaction occurring after mast cell activation. The present report highlights some of the more recent developments in the mechanisms of AD which can be important in understanding and treating this troublesome disease.
authors: Department of Paediatrics, University Hospital Antwerp, Belgium.
authors: H P
authors: HP
authors: Van Bever
mesh_terms: D000485:Allergens / Q000276:immunology; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D004391:Dust; D004804:Eosinophils / Q000276:immunology; D005512:Food Hypersensitivity / Q000150:complications; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D007801:Langerhans Cells / Q000276:immunology; D008407:Mast Cells / Q000276:immunology; D012882:Skin Tests
chemical_list: D000485:Allergens; D004391:Dust; D007073:Immunoglobulin E