Alveolar ridge augmentation by osteoinductive materials in goats.
The purpose of the present study was to determine whether alveolar ridge augmentation could be induced in goats. In 12 male goats allogenic, demineralized, and lyophilized dentin or bone was implanted subperiosteally on the buccal sides of the natural edentulous regions of the alveolar process of the mandible. Light microscopic evaluation revealed fibrous encapsulation, a few multinuclear giant cells, little inflammatory reaction, and no osteoinduction. It was concluded that no osteoinduction took place in goats.
Pinholt
E M
EM
Institute for Surgical Research, Rikshospitalet, University of Oslo, Norway.
Haanaes
H R
HR
Roervik
M
M
Donath
K
K
Bang
G
G
D000540:Alveolar Ridge Augmentation / Q000379:methods*; D000818:Animals; D001862:Bone Resorption / Q000473:pathology; D016025:Bone Transplantation / Q000379:methods*; D003238:Connective Tissue / Q000473:pathology; D003648:Decalcification Technique; D003804:Dentin / Q000637:transplantation*; D004195:Disease Models, Animal; D005612:Freeze Drying; D006041:Goats; D008297:Male; D008334:Mandible / Q000473:pathology / Q000601:surgery*; D009132:Muscles / Q000473:pathology / Q000601:surgery; D010012:Osteogenesis / Q000502:physiology; D014021:Tissue Preservation; D014945:Wound Healing