title: [Controversy--surgical vs. medical management of inflammatory bowel disease].
abstract: The controversy in the treatment of inflammatory bowel disease is how to decide surgical vs. medical management in each case. Of 309 patients with ulcerative colitis in our department, 63 (20%) patients had received surgical treatment. The mean age was 33.5 +/- 13.7 years old and the mean duration from onset to operation was 6.72 +/- 5.51 years. The indications for surgical treatment were 47 (75%) resistant cases against medical treatment, 9 (14%) severe cases and 7 (11%) cancer or dysplasia cases. In surgical cases compared with medical ones, the ratio of total duration (months)/number of admission showed below 10, and the total amount of used steroid was over 300 mg per month. These ratios were considered to be the useful markers for surgical indication. Operative procedures were 15 total proctocolectomy+ileostomy, 29 total colectomy+ileorectal anastomosis, 13 total proctocolectomy+ileoanal anastomosis and 6 others. Restorative proctocolectomy using double stapling method with two stage operation was chosen in 8 patients because of easier and safer operative procedure and a few complications. We conclude that early surgical treatment for the patients resistant against medical management is considered to improve the patients' quality of life.
authors: First Department of Surgery, University of Tokyo, Japan.
authors: Y
authors: Y
authors: Kubota
authors: T
authors: T
authors: Sawada
authors: T
authors: T
authors: Muto
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003082:Colectomy; D005260:Female; D006801:Humans; D007081:Ileostomy; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage; D016737:Proctocolectomy, Restorative; D011788:Quality of Life; D012189:Retrospective Studies
chemical_list: D011239:Prednisolone