Amyotrophic lateral sclerosis associated with the syndrome of inappropriate secretion of antidiuretic hormone.
A 71-year-old female with amyotrophic lateral sclerosis (ALS) developed the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) during respiratory failure due to atrophy of the respiratory muscles. Serum sodium concentration fell to 116 mEq/l and then returned to the normal range after water restriction and respiratory care. This is considered to be the first case report of ALS associated with SIADH.
Motoo
Y
Y
Department of Internal Medicine, Kanazawa University, Japan.
Ohta
H
H
Okai
T
T
Sawabu
N
N
D000368:Aged; D000690:Amyotrophic Lateral Sclerosis / Q000150:complications* / Q000175:diagnosis; D001774:Blood Chemical Analysis; D004576:Electromyography; D005260:Female; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000175:diagnosis / Q000209:etiology*; D012131:Respiratory Insufficiency / Q000150:complications / Q000209:etiology; D012964:Sodium / Q000097:blood / Q000652:urine; D014667:Vasopressins / Q000097:blood
D014667:Vasopressins; D012964:Sodium