[Neuronal migration anomalies. The magnetic resonance aspects of some types].
The authors investigated the value of magnetic resonance (MR) imaging in the evaluation of some types of neuronal migration anomaly. During pregnancy, a radial neuronal migration from germinal matrix to cortex occurs in the fetal brain, and 6 layers are formed. Infections, traumas, vascular factors can block the migration. Neuronal migration disorders are divided into 5 different classes: (1) agyria-pachigyria complex; (2) schizencephaly; (3) polymicrogyria; (4) unilateral megaencephaly; (5) heterotopia. In this study, 12 patients were evaluated with MR imaging: 5 had lissencephaly, 4 heterotopia and 3 schizencephaly (2 with open lips, and 1 with closed lips). MR imaging is the method of choice in these patients; indeed, characteristic morphologic and signal patterns allow the correct evaluation and diagnosis of neuronal migration anomalies in all cases.
Muto
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M
Servizio di Neuroradiologia, Ospedale Loreto Nuovo, Napoli.
Wang
H
H
D000293:Adolescent; D000328:Adult; D002465:Cell Movement; D002540:Cerebral Cortex / Q000002:abnormalities* / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009474:Neurons / Q000473:pathology*
Disturbi della migrazione neuronale. Aspetti con Risonanza Magnetica di alcuni tipi.