title: [Results of tuberculosis treatment in a health district in Zaire].
abstract: The results of the treatment of tuberculosis have been evaluated among 407 patients distributed into 268 cases of pulmonary tuberculosis with positive smears (TP+), 70 pulmonary forms with negative smears (TP-) and 69 cases of extrapulmonary tuberculosis (TEP). A group 1 of 361 patients including new cases and late relapses and consisting of 236 TP+, 59 TP- and 66 TEP has been put through the treatment pattern: 2S6H7T7 + 10H7T7 or 2S6H7 + 10S2H2. Group 2, of 21 patients consisting of failures, early relapses and previously but irregularly treated cases, was given a pattern: 2R7E7H7Z7 + 10R2H2. In group 3, 25 new cases were given a short treatment: 2R7E7H7Z7 + 4R7H7. In group 1 we have recorded 68.42% cured patients, 8.59% failures and 14.40% neglects of treatment. The remaining 8.59% include deceased, transfers and patients put through extended treatment. The rate of cure was better among TEP patients (95.46%) than among TP- patients (79.66%) and TP+ patients (58.05%); failures were proved to be more frequent among TP+ patients (11.88%) than among TP- patients (3.39%) and TEP patients (1.51%). In group 2 and 3 successes have amounted to 95.24% and 84% respectively. Considering rates of cure, irregular treatments, neglects and failures with standard patterns (group 1), it appears to be desirable that rifampicin-including short patterns are added to antitubercular therapeutic strategies of developing countries.
authors: Service de Pneumologie, UCL, Mont-Godinne, Yvoir, Belgique.
authors: C
authors: C
authors: Karhahunga
authors: J
authors: J
authors: Hardy
authors: T
authors: T
authors: Kayembe
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D016009:Chi-Square Distribution; D015023:Democratic Republic of the Congo / Q000453:epidemiology; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D014376:Tuberculosis / Q000188:drug therapy* / Q000453:epidemiology; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents
vernacular_title: Résultats du traitement de la tuberculose dans une zone de santé au Zäire.