[Effects of melatonin and epiphysectomy on electrical activity of the rat brain at different times of the day].
The pineal hormone melatonin in a dose-effect manner (0.1, 1 and 10 mg/kg) reorganized EEG spectral characteristics of rat sensorimotor cortex and hippocampus, decreasing medium (6-12 Hz) and high frequency (12-22 Hz) waves only in the evening. On the contrary, pinealectomy increased high-frequency waves only during morning hours. It is suggested that the observed changes may accompany anxiolytic and hypnotic effects of melatonin.
Botvev Orkhiĭ
P
P
Nerobkova
L N
LN
Voronina
T A
TA
Arushanian
E B
EB
D000818:Animals; D001921:Brain / Q000502:physiology*; D002940:Circadian Rhythm; D004569:Electroencephalography; D006624:Hippocampus / Q000502:physiology; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D009044:Motor Cortex / Q000502:physiology; D010870:Pineal Gland / Q000601:surgery*; D051381:Rats; D013003:Somatosensory Cortex / Q000502:physiology
D008550:Melatonin
Vliianie melatonina i épifizéktomii na élektricheskuiu aktivnost' mozga krys v razlichnoe vremia sutok.