Crohn's disease presenting as unilateral labial hypertrophy.
We describe a child who had unilateral hypertrophy of the vulva, a rare extraintestinal manifestation of Crohn's disease. A biopsy specimen revealed a noncaseating granuloma. Flexible sigmoidoscopic examination revealed punctate 1 mm lesions with surrounding erythema in the rectum and sigmoid colon. Response to treatment with sulfasalazine was excellent. Gastrointestinal symptoms developed 1 year later when sulfasalazine was discontinued.
Werlin
S L
SL
Department of Pediatrics, Medical College of Wisconsin, Milwaukee 53226.
Esterly
N B
NB
Oechler
H
H
D002648:Child; D003424:Crohn Disease / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006099:Granuloma / Q000175:diagnosis; D006801:Humans; D006984:Hypertrophy; D012008:Recurrence; D014844:Vulva / Q000473:pathology*; D014845:Vulvar Diseases / Q000175:diagnosis