[Increased tension on the sympathetic nervous system in arrhythmogenic right ventricular dysplasia. Participation in etiopathogenesis?].
To evaluate the suspected role of sympathetic nerve tone in pathogenesis of arrhythmogenic right ventricle dysplasia (ARVD), noradrenaline (NOR) and adrenaline (AD) plasma levels were determined by radioenzymatic method in 10 pts with ARVD (mean age 36 y, VT-8 pts, syncope-5) at rest and during peak exercise. 9 healthy men (mean age 28 y) served as control.


RESULTS
[table: see text]


CONCLUSIONS
Significant increase of norepinephrine serum level during peak exercise suggests essential role of sympathetic nerve tone in pathogenesis of ARVD.
Włodarska
E K
EK
Kliniki Szybkiej Diagnostyki, Instytut Kardiologii, Warszawa.
Pszona
A
A
Popławska
W
W
Rydlewska-Sadowska
W
W
Baranowski
R
R
Borowiecka
E
E
Chojnowska
L
L
Ruzyłło
W
W
D000328:Adult; D001145:Arrhythmias, Cardiac / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D004837:Epinephrine / Q000097:blood*; D015444:Exercise / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000097:blood*; D012016:Reference Values; D013564:Sympathetic Nervous System / Q000503:physiopathology*; D016278:Ventricular Function, Right / Q000502:physiology*
D009638:Norepinephrine; D004837:Epinephrine
Wzmozone napiecie układu sympatycznego w arytmogennej dysplazji prawej komory. Udział w etiopatogenezie?