title: Pyoderma gangrenosum, polycythemia rubra vera, and the development of leukemia.
abstract: A patient with long-standing, well-controlled polycythemia rubra vera developed recurrent episodes of bullous pyoderma gangrenosum followed by the transformation of his hematologic disease into a rapidly progressive acute myeloid leukemia. This case, together with previously described patients, indicates that the appearance of bullous pyoderma gangrenosum in a patient with polycythemia rubra vera is often of ominous prognostic significance.
authors: Regional Centre of Dermatology, Mater Misericordiae Hospital, Dublin, Ireland.
authors: K K
authors: KK
authors: Ho
authors: B W
authors: BW
authors: Otridge
authors: E
authors: E
authors: Vandenberg
authors: F C
authors: FC
authors: Powell
mesh_terms: D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011087:Polycythemia Vera / Q000150:complications* / Q000473:pathology; D011379:Prognosis; D017511:Pyoderma Gangrenosum / Q000209:etiology* / Q000473:pathology; D012008:Recurrence