title: Activation of MPF in fission yeast.
abstract: In fission yeast p34cdc2/cyclin is activated at the G2/M boundary by dephosphorylation of Tyr15 of the p34cdc2 subunit. Two protein phosphatases carry out this dephosphorylation event. The major activity is encoded by cdc25, which is a distantly related member of the protein tyrosine phosphatase family. A minor activity is provided by a newly identified fission yeast protein tyrosine phosphatase.
authors: Department of Molecular, Scripps Research Institute, La Jolla, CA 92037.
authors: J B
authors: JB
authors: Millar
authors: G
authors: G
authors: Lenaers
authors: C
authors: C
authors: McGowan
authors: P
authors: P
authors: Russell
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D016203:CDC2 Protein Kinase / Q000502:physiology; D003545:Cysteine / Q000235:genetics; D005656:Fungal Proteins / Q000302:isolation & purification / Q000378:metabolism; D005815:Genetic Code / Q000235:genetics*; D006801:Humans; D066298:In Vitro Techniques; D016200:Maturation-Promoting Factor / Q000502:physiology*; D008969:Molecular Sequence Data; D010766:Phosphorylation; D012568:Schizosaccharomyces / Q000502:physiology*
chemical_list: D005656:Fungal Proteins; D016203:CDC2 Protein Kinase; D016200:Maturation-Promoting Factor; D003545:Cysteine