[Effects of alcoholic intoxication in the antenatal period on the development of male germ cells].
During 1-20 days of pregnancy rats were given 20% alcohol orally in a dose 0.4 mg/kg bw. This led to a significant increase in the nuclear volume of germ cells in male 19-day embryos. A karyological analysis of 2-month offspring germ cell generations at stage VII of seminiferous epithelium cycle revealed a reliable decrease in the number of spermatids on step 7 of development after introduction of antenatal alcohol. The increased proportion of spermatocytes with meiotic chromosomes pathological behaviour due to alcohol was determined by the proposed quantitative analysis of meiotic divisions.
Khil'kevich
L V
LV
Kirilo
L F
LF
D000818:Animals; D002869:Chromosome Aberrations; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000235:genetics* / Q000473:pathology; D008297:Male; D011247:Pregnancy; D051381:Rats; D013087:Spermatids / Q000648:ultrastructure; D013094:Spermatozoa / Q000648:ultrastructure; D013997:Time Factors
Vliianie alkogol'noĭ intoksikatsii v antenatal'nom periode na razvitie muzhskikh polovykh kletok krys.