Determination of cadmium in biological samples by inductively coupled plasma atomic emission spectrometry after extraction with 1,5-bis(di-2-pyridylmethylene) thiocarbonohydrazide.
An inductively coupled plasma atomic emission spectrometric method for the determination of trace amounts of cadmium after extraction of the metal into isobutyl methyl ketone containing 1,5-bis(di-2-pyridylmethylene) thiocarbonohydrazide is described. The optimum extraction conditions were evaluated from a critical study of the effects of pH, concentration of extractant, shaking time and ionic strength. The detection limit for cadmium is 0.1 ng ml-1 and the calibration is linear from 0.2 to 140 ng ml-1. The relative standard deviation for ten replicate measurements is 2.9% for 2 ng ml-1 of cadmium. Results from the analysis of some certified biological reference materials are given.
Espinosa Almendro
J M
JM
Department of Analytical Chemistry, Faculty of Sciences, University of Málaga, Spain.
Bosch Ojeda
C
C
Garcia de Torres
A
A
Cano Pavón
J M
JM
D000818:Animals; D002104:Cadmium / Q000032:analysis*; D006834:Hydrazines; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents; D008742:Methyl n-Butyl Ketone; D008832:Microchemistry; D011725:Pyridines; D013057:Spectrum Analysis / Q000379:methods* / Q000592:standards
D006834:Hydrazines; D007202:Indicators and Reagents; D011725:Pyridines; D002104:Cadmium; D008742:Methyl n-Butyl Ketone; C079106:1,5-bis(di-2-pyridylmethylene)thiocarbonohydrazide; C005458:methyl isobutyl ketone