[Ultrastructural and morphometric studies on lesions in experimental membranous glomerulonephritis (MGN) of rabbits].
Lesions of experimental MGN in rabbits were studied by transmission and scanning electron microscopy, and the size of epithelial deposits as well as the thickness of GBM were measured by using stereological quantitative method in image analysis system. Results showed that changes of the morphological parameters could be measured and analysed objectively with accuracy. Morphometric study is beneficial to investigate the relationship between morphological lesions and functional changes, and it can also provide quantitative data of the morphological change in evaluating the curative effect of drugs for glomerulonephritis.
Zhu
L Q
LQ
Department of Pathology, Beijing College of Traditional Chinese Medicine.
D000818:Animals; D001485:Basement Membrane / Q000648:ultrastructure; D015433:Glomerulonephritis, Membranous / Q000139:chemically induced / Q000473:pathology*; D007091:Image Processing, Computer-Assisted; D007678:Kidney Glomerulus / Q000648:ultrastructure*; D008297:Male; D011817:Rabbits; D012710:Serum Albumin, Bovine
D012710:Serum Albumin, Bovine