title: Ageing, information and the magical number seven.
abstract: Concepts from information theory are applied to human ageing. An equation is derived, based on the general properties of information systems, which closely predicts the mortality rate in old age. The same equation predicts that infection will be increasingly severe when first exposure to micro-organisms is delayed leading to diseases which peak in early and middle age. A parameter of the equation is the level of redundancy in human information processing. Observed mortality rates show that this is sevenfold and it is suggested that seven is a fundamental dimensionless biological constant.
authors: Department of Pathology, Lancaster Moor Hospital, UK.
authors: J A
authors: JA
authors: Morris
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging; D003662:Decision Theory; D004813:Epidemiology; D005260:Female; D006801:Humans; D007257:Information Theory; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D009026:Mortality