title: [MR imaging of degenerative lumbar disc disease emphasizing on signal intensity changes in vertebral body].
abstract: Magnetic resonance imaging was performed in 400 patients with degenerative disc disease. Signal changes and their sites in the vertebral body were classified and referred to narrowing of the intervertebral disc space. MR findings were compared with those of plain roentgenograms of the lumbar spine. Signal changes in the vertebral body were noted in 83 cases (102 vertebral bodies). Low-intensity abnormality on both T1- and T2-weighted images (WI) was the most common finding, and was most frequently seen at the end plate and/or the angle. These changes were correlated with narrowing of the disc space and osteosclerosis on the plain roentgenogram of the lumbar spine. Signal changes occasionally occurred in the inner region of the vertebral body, and these lesions tended to show a high-intensity abnormality on T1-WI. We conclude that signal changes in degenerative disc disease are not specific, but are sometimes difficult to distinguish from the signal changes in other conditions such as spinal tumor or bone marrow disorder.
authors: Department of Radiology, Jikei University School of Medicine.
authors: K
authors: K
authors: Toyoda
authors: M
authors: M
authors: Ida
authors: Y
authors: Y
authors: Murakami
authors: J
authors: J
authors: Harada
authors: S
authors: S
authors: Tada
mesh_terms: D006801:Humans; D007403:Intervertebral Disc / Q000473:pathology*; D007564:Japan / Q000453:epidemiology; D008159:Lumbar Vertebrae / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D012189:Retrospective Studies; D013122:Spinal Diseases / Q000175:diagnosis* / Q000453:epidemiology