title: Primary melanoma of urinary bladder.
abstract: The fourth case of primary melanoma of the bladder is presented together with a review of the previously reported cases and the relevant literature on malignant melanoma in urology. The criteria for classification of the bladder lesion as the primary site are discussed. The eighty-one-year-old female patient was felt not to be suitable for extensive surgery and was successfully treated with a combination of radiation and immunotherapy with recombinant alpha 2 interferon. After previous monthly recurrences of the tumor the patient is in complete remission fifteen months after initiation of therapy. It appears that this form of treatment might be a valuable alternative to radical surgery in elderly patients.
authors: Department of Urology, University of Bonn, Germany.
authors: H
authors: H
authors: Van Ahlen
authors: V
authors: V
authors: Nicolas
authors: W
authors: W
authors: Lenz
authors: I
authors: I
authors: Boldt
authors: A
authors: A
authors: Bockisch
authors: W
authors: W
authors: Vahlensieck
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D015994:Incidence; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use; D008545:Melanoma / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D011879:Radiotherapy Dosage; D011994:Recombinant Proteins; D001743:Urinary Bladder / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000628:therapy
chemical_list: D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins