[Antiarrhythmic amidinohydrazone substituted benzophenones. 2. Preparation and determination of configuration of (Z)- and (E)-2-amino-5-chlorobenzophenone amidinohydrazone salts].
The configurational isomers of the 2-amino-5-chlorbenzophenoneamidinohydrazones could be obtained as TLC pure samples by fractionating crystallization of the product mixture. The determination of their configuration by comparison of the UV spectra with the corresponding oximes could be confirmed by X-ray structure analysis.
Richter
P H
PH
Fachbereich Pharmazie Ernst-Moritz-Arndt-Universität Greifswald.
Schleuder
M
M
Reck
G
G
Hagen
A
A
D000889:Anti-Arrhythmia Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001577:Benzophenones / Q000138:chemical synthesis* / Q000494:pharmacology; D002855:Chromatography, Thin Layer; D003460:Crystallization; D006835:Hydrazones / Q000138:chemical synthesis* / Q000494:pharmacology; D008968:Molecular Conformation; D013056:Spectrophotometry, Ultraviolet; D014961:X-Ray Diffraction
D000889:Anti-Arrhythmia Agents; D001577:Benzophenones; D006835:Hydrazones; C079368:2-amino-5-chlorobenzophenoneamidinohydrazone
Antiarrhythmisch wirksame Amidinohydrazone substituierter Benzophenone. 2. Mitteilung: Darstellung und Konfigurationszuordnung von (Z)- und (E)-2-Amino-5-chlorbenzophenonamidinohydrazonsalzen.