Medulloblastoma in children and in adults: a comparative study.
We report on the clinical and pathological characters and factors influencing prognosis in a consecutive series of 20 cases of medulloblastoma presenting in childhood and of 20 cases of the tumour presenting in adulthood. The significant differences which emerged were compared with the findings of the largest published series. Medulloblastoma is more often lateral in site and desmoplastic in histology in adults than in children. On our evidence the age at tumour onset not affect survival.
Maleci
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A
Department of Neurological Sciences Neurosurgery, La Sapienza University of Rome, Italy.
Cervoni
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L
Delfini
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R
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002528:Cerebellar Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002531:Cerebellum / Q000473:pathology / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008527:Medulloblastoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D009367:Neoplasm Staging; D012189:Retrospective Studies; D012737:Sex Factors; D015996:Survival Rate; D014057:Tomography, X-Ray Computed