14-3-3 proteins: a highly conserved, widespread family of eukaryotic proteins.
A family of proteins known as 14-3-3 is currently receiving increased attention by investigators studying a broad range of biological systems, including plants and invertebrates. The outstanding feature of this family is the extraordinarily high sequence conservation observed. Current thinking indicates that these proteins may function as regulators in signal transduction/phosphorylation mechanisms.
Aitken
A
A
Laboratory of Protein Structure, National Institute for Medical Research, Mill Hill, London, UK.
Collinge
D B
DB
van Heusden
B P
BP
Isobe
T
T
Roseboom
P H
PH
Rosenfeld
G
G
Soll
J
J
D048948:14-3-3 Proteins; D000595:Amino Acid Sequence; D000818:Animals; D017124:Conserved Sequence; D005057:Eukaryotic Cells / Q000502:physiology*; D006801:Humans; D008969:Molecular Sequence Data; D009419:Nerve Tissue Proteins / Q000737:chemistry / Q000502:physiology*; D010766:Phosphorylation; D010944:Plants; D011493:Protein Kinase C / Q000037:antagonists & inhibitors*; D015398:Signal Transduction; D014446:Tyrosine 3-Monooxygenase
D048948:14-3-3 Proteins; D009419:Nerve Tissue Proteins; D014446:Tyrosine 3-Monooxygenase; D011493:Protein Kinase C