[The effect of antibodies against Ca2(+)-ATPase and its hydrophobic fragment on the activity of this enzyme and on the passive transport of Ca2(+)].
It is shown that both Ca(2+)-ATPase and its hydrophobic fragment are immunogenic factors. A region between hydrophobic and hydrophilic parts of Ca(2+)-ATP-ase is immunogenic. These antibodies clearly inhibit inflow and outflow of Ca2+ through a hydrophobic fragment reconstructed into liposomes and do not influence Ca(2+)-ATPase activity.
Kurskiĭ
M D
MD
Fedorov
A N
AN
Dibrova
T L
TL
Ermekova
V M
VM
Chevpilo
I A
IA
Shaturskiĭ
O Ia
OIa
Afonina
G V
GV
Piskarev
V B
VB
D000818:Animals; D000906:Antibodies / Q000302:isolation & purification / Q000494:pharmacology*; D000937:Antigen-Antibody Reactions / Q000276:immunology; D001692:Biological Transport / Q000276:immunology; D002118:Calcium / Q000378:metabolism*; D000252:Calcium-Transporting ATPases / Q000276:immunology* / Q000378:metabolism; D002645:Chickens; D005260:Female; D007114:Immunization; D012519:Sarcoplasmic Reticulum / Q000201:enzymology; D012995:Solubility
D000906:Antibodies; D000252:Calcium-Transporting ATPases; D002118:Calcium
Vliianie antitel protiv Ca2(+)-ATPazy i ee gidrofobnogo fragmenta na aktivnost' étogo fermenta i passivnyĭ transport Ca2(+).