Enalapril in hypertension.
Twenty five patients of mild to moderate uncomplicated essential hypertension and five with severe hypertension were treated with long acting converting enzyme inhibitor enalapril for six weeks. Diuretic was added in those patients who did not respond satisfactorily. Twenty one patients of mild to moderate hypertension had their diastolic blood pressure controlled at the end of the study; fifteen with enalapril alone and six with the help of diuretic. Remaining four showed a relative fall but not to level below 150/90 mm Hg. Only one patient with severe hypertension showed fall to normal levels. Four showed a relative fall but not to the normal level even with the addition of a diuretic. Enalapril is an effective anti hypertensive drug in mild to moderate essential hypertension.
Misra
N P
NP
Department of Medicine, Gandhi Medical College & Associated Hospitals, Bhopal, India.
Verma
Y
Y
Shah
J Y
JY
D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D004359:Drug Therapy, Combination; D004656:Enalapril / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000627:therapeutic use; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged
D006852:Hydrochlorothiazide; D004656:Enalapril