Lithium effect on smooth pursuit eye movements of healthy volunteers.
Smooth pursuit eye movement (SPEM) dysfunctions in major affective disorder patients have been reported to be associated with lithium treatment. We report that SPEM of 13 healthy volunteers, either taking lithium (n = 7) or placebo (n = 6), were not significantly impaired by lithium. This could point to a pathophysiologic difference between affective disorder patients and a normal population.
Flechtner
K M
KM
Psychiatrische Klinik, Freien Universität Berlin, Germany.
Mackert
A
A
Thies
K
K
Frick
K
K
Müller-Oerlinghausen
B
B
D000328:Adult; D004311:Double-Blind Method; D004569:Electroencephalography / Q000295:instrumentation; D004585:Electrooculography / Q000295:instrumentation; D005583:Fourier Analysis; D006801:Humans; D016651:Lithium Carbonate / Q000494:pharmacology*; D008297:Male; D011698:Pursuit, Smooth / Q000187:drug effects*; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation
D016651:Lithium Carbonate