[Assessment of vitamin B2, B6, and PP supply from data on excretion of vitamins and their metabolites in alimentary iron and riboflavin deficiency].
Alimentary deficiency in riboflavin and/or iron in rats involved distinct decrease in excretion of 4-pyridoxylic acid and 1-N-methyl nicotinamide--the metabolites considered as the indices of vitamins B6 and PP consumption. The effect observed appears to occur due to a decrease in activity of some iron- and flavin-containing enzymes participating in the metabolism of pyridoxine and niacin. Addition to the diet of the deficient component normalized these patterns. Use of the data on excretion of 4-pyridoxylic acid and 1-N-methyl nicotinamide as criteria of consumption of pyridoxine and niacin is discussed.
Alekseeva
I A
IA
Kodentsova
V M
VM
Vrzhesinskaia
O A
OA
Zvereva
T E
TE
Khotimchenko
S A
SA
Spirichev
V B
VB
D000818:Animals; D004032:Diet; D000090463:Iron Deficiencies; D008297:Male; D009536:Niacinamide / Q000031:analogs & derivatives / Q000378:metabolism* / Q000652:urine; D011736:Pyridoxine / Q000378:metabolism* / Q000652:urine; D051381:Rats; D017208:Rats, Wistar; D012256:Riboflavin / Q000378:metabolism* / Q000652:urine; D012257:Riboflavin Deficiency / Q000652:urine*
D009536:Niacinamide; D011736:Pyridoxine; D012256:Riboflavin; C008472:N-methylnicotinamide
K otsenke obespecehnnosti organizma vitaminami B2, B6, i PP po dannym ékskretsii vitaminov i ikh metabolitov pri alimentarnom defitsite zheleza i riboflavina.