[A case of primary orbital T-cell lymphoma].
A 46-year-old man presented with eyelid swelling and choroidal folds in the right eye. These symptoms were rapidly exacerbated, but inflammatory findings were not observed. MRI tomography confirmed the presence of an orbital tumor compressing the eyeball. In 67Ga scintigram, a hot spot was recognized only at the right orbital region. This orbital tumor was removed subtotally. It was diagnosed histologically as non-Hodgkin malignant lymphoma (diffuse medium cell-type) and stained on paraffin sections, using monoclonal antibodies immunohistochemically. Anti-LCA, anti-MT-1, anti-UCHL-1 antibodies were positive, and anti-MB-1 antibody was negative. The clinical stage was IE in the Ann-Arbor classification. He was treated by radiation and chemotherapy, but died because of opportunistic infection after 6 months. This is, so far as we know, the first case in Japan diagnosed as primary orbital T-cell type malignant lymphoma immunohistochemically.
Hirasaka
T
T
Department of Ophthalmology, Kobe University School of Medicine, Japan.
Sahori
A
A
Inoue
M
M
Morino
I
I
Chaoliang
H
H
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D016399:Lymphoma, T-Cell / Q000175:diagnosis* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000473:pathology; D014057:Tomography, X-Ray Computed
D000911:Antibodies, Monoclonal; D000954:Antigens, Surface