Problems in performing a double-blind multicenter study using a hypnotic in private practice.
1. The procedure described--the immediate data transfer and entry system (ITES)--is suitable to improve the quality of data collected in multicentre studies in private practice. 2. The results of the study show that regarding influence on sleep quality and daytime well-being the non-benzodiazepine Z is significantly superior to placebo and slightly superior to the benzodiazepines F and T. 3. The advantage of Z treatment is the better daytime well-being after taking the hypnotic for sleep induction the night before. 4. This study shows that a quality standard equal to that in clinical practice may be achieved in private practice.
Fischer
W
W
Rhône-Poulenc Rorer GmbH, Cologne, Germany.
Haase
W
W
Rüther
E
E
Clarenbach
P
P
Hajak
G
G
D000293:Adolescent; D000328:Adult; D000368:Aged; D004311:Double-Blind Method; D005194:Family Practice; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D016032:Randomized Controlled Trials as Topic; D012893:Sleep Wake Disorders / Q000188:drug therapy* / Q000523:psychology
D006993:Hypnotics and Sedatives