Hyperprolactinemia and lens opacities.
We report the presence of lens opacities in patients with prolactin-secreting microadenomas of the pituitary gland. The occurrence of lens opacities was related to prolactin serum levels and appeared only in women. The mechanism by which prolactin induces cataract is not known, although this hormone could affect the lens's permeability to ions, water, sugars, and amino acids. Moreover, the lens opacities found in women but not in men seem to indicate synergism with estrogens.
Costagliola
C
C
Eye Clinic, 1st School of Medicine, Federico II University, Naples, Italy.
Mastropasqua
L
L
Amato
G
G
Carella
C
C
D000328:Adult; D001971:Bromocriptine / Q000627:therapeutic use; D002386:Cataract / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006966:Hyperprolactinemia / Q000150:complications* / Q000188:drug therapy; D008297:Male; D010911:Pituitary Neoplasms / Q000150:complications / Q000188:drug therapy; D011388:Prolactin / Q000097:blood; D015175:Prolactinoma / Q000150:complications / Q000188:drug therapy; D012737:Sex Factors
D001971:Bromocriptine; D011388:Prolactin