[Lowering increased cholesterol--prolonging life?].
Epidemiologic surveys reveal a positive correlation between serum cholesterol levels and the incidence of coronary artery disease. Intervention trials demonstrated that a reduction of serum cholesterol by 1% results in a decrease of coronary non-fatal events by 2%. Fatal coronary events remain almost uninfluenced. On the other side, several intervention trials showed an excess mortality from non-cardiac causes in the therapy groups (i.e. malignant tumors, suicides, accidents). Thus, until now no prolongation of life expectancy could be verified by cholesterol lowering measures.
Klepzig
H
H
Abteilung für Kardiologie, Universität Frankfurt a. M.
Kaltenbach
M
M
D002423:Cause of Death; D002784:Cholesterol / Q000097:blood*; D003327:Coronary Disease / Q000401:mortality* / Q000517:prevention & control; D006801:Humans; D006937:Hypercholesterolemia / Q000401:mortality* / Q000517:prevention & control; D015996:Survival Rate
D002784:Cholesterol
Erhöhtes Cholesterin senken--Leben verlängern?