Variation of perfluoropropane disappearance after vitrectomy.
In complex cases of retinal detachment, perfluoropropane (C3F8) is frequently used after vitrectomy for tamponade of retinal breaks. Results of previous studies of C3F8 disappearance using 10% C3F8 after vitrectomy in human eyes have differed significantly. A wide variation in the decay rate and half life of C3F8 after vitrectomy was observed in eyes that had similar clinical settings and received the same C3F8 concentration (15%, 20%, or 25%). This occurred even in those eyes where there was no change in the geometric contour of the eye after a repeat vitrectomy.
Meyers
S M
SM
The Cleveland Clinic Foundation, Department of Ophthalmology, OH 44195-5524.
Ambler
J S
JS
Tan
M
M
Werner
J C
JC
Huang
S S
SS
D005123:Eye / Q000378:metabolism; D005466:Fluorocarbons / Q000493:pharmacokinetics*; D005500:Follow-Up Studies; D006207:Half-Life; D006801:Humans; D011446:Prospective Studies; D012086:Reoperation; D012163:Retinal Detachment / Q000601:surgery; D014821:Vitrectomy
D005466:Fluorocarbons; C042852:perflutren