[The nuclear roundness factor as a parameter in the anatomoclinical correlation of prostatic carcinoma].
This paper correlates the nuclear roundness factor to clinical stage, patient's age and acid phosphatase level at the time of diagnosis in a group of 48 patients with prostate carcinoma and a minimal follow-up of 5 years. It has been demonstrated that, from an anatomo-clinical point of view, the nuclear roundness factor is a good indicator because it presents increasing values as the clinical stage of tumoral extension worsens, and in those stages where the number of patients was relatively high the average of deaths was always higher than that of survivors. On the other hand, a direct correlation to total acid phosphatase, and an inverse correlation to age at the time of diagnosis was shown in patients with changes in these values.
Alvarez-Ossorio
J
J
Departamento de Biología Celular y Anatomía Patológica, Universidad de Cádiz.
López
A
A
Vilches
J
J
Salido
M
M
Castiñeiras
J
J
Aparicio
J
J
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002467:Cell Nucleus / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011471:Prostatic Neoplasms / Q000473:pathology*
El factor de redondez nuclear como parámetro en la correlación anatomoclínica del carcinoma prostático.