[Assay of adenine nucleotide level in platelet storage pool for evaluation of the course of hemoblastosis].
The content of adenine nucleotides (ATP, ADP) was studied in dense granules of platelets in hemoblastosis to estimate the character of the pathological process course. Varying biochemical defects were observed at the levels of ATP and ADP depending on the severity of the pathological process in chronic myeloid leukemia, acute lymphoblastic leukemia, acute myeloblastic and acute myelo-monoblastic leukemias. Adenine nucleotide values can be used for the diagnosis of varying stages of the above diseases, for the evaluation of anomalous platelets and characterization of the adequacy of the bone marrow hemopoiesis.
Mareeva
T B
TB
Pestina
T I
TI
Morozova
N G
NG
Sokovnina
Ia M
IaM
D000227:Adenine Nucleotides / Q000097:blood*; D001792:Blood Platelets / Q000378:metabolism*; D006801:Humans; D007938:Leukemia / Q000097:blood*
D000227:Adenine Nucleotides
Issledovanie urovnia adeninnukleotidov pula khraneniia trombotsitov dlia otsenki techeniia gemoblastozov.