title: Effects of long-term running on lymphocyte subpopulations.
abstract: Thirteen healthy members (11 males and 2 females; mean age 19.8 years) of an athletic club underwent a long-term exercise program (five 8-km runnings per week for 40 weeks) as regular training for their club. The circulating lymphocyte number, T lymphocyte percentage, and OKT4/OKT8 ratio did not change through the 40-week training period. However, suppressor/inducer (Leu3a+Leu8+) and suppressor T cells (Leu2a+Leu15+) significantly increased. In contrast, helper (Leu3a+Leu8-) and cytotoxic T cells (Leu2a+Leu15-) significantly decreased. On the other hand, there was no change in three males (mean age 18.7 years) without the long-term exercise program. These results suggest that long-term running may induce some change in lymphocyte subpopulations.
authors: Department of Medicine, Gunma University School of Medicine, Kusatsu, Japan.
authors: E
authors: E
authors: Kawada
authors: K
authors: K
authors: Kubota
authors: H
authors: H
authors: Kurabayashi
authors: K
authors: K
authors: Tamura
authors: J
authors: J
authors: Tamura
authors: T
authors: T
authors: Shirakura
mesh_terms: D000328:Adult; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D016131:Lymphocyte Subsets / Q000502:physiology*; D008297:Male; D012420:Running; D013601:T-Lymphocytes / Q000502:physiology; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology / Q000502:physiology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology / Q000502:physiology