Fine needle aspiration biopsy of solid tumours by auto-vacuum system: a study in rats.
A fine needle aspiration biopsy (FNAB) device was designed to utilize a steel spring located between the syringe and its plunger, which exerts a constant negative pressure (auto-vacuum). In 43 rats inoculated with breast tumour cells, the technique was compared with the standard procedure of FNAB (21 Sp1 and 22 Walker256 carcinosarcoma). Malignant cells were cytologically confirmed in all cases. Sufficient material was obtained in 95% of FNAB by auto-vacuum system versus 86% by standard technique. The superior results obtained with the auto-vacuum system was seen for both soft and hard tumours.
de Freitas Júnior
R
R
Department of Gynecology and Obstetrics, Universidade Estadual de Campinas, Brazil.
Giraldo
P C
PC
Rettori
O
O
Vieira-Matos
A N
AN
Tambascia
J K
JK
D000818:Animals; D001707:Biopsy, Needle / Q000295:instrumentation* / Q000379:methods; D002279:Carcinoma 256, Walker / Q000473:pathology; D008325:Mammary Neoplasms, Experimental / Q000473:pathology*; D051381:Rats; D011919:Rats, Inbred Strains; D017208:Rats, Wistar; D014618:Vacuum