[The validation of the use of Moradol for anesthesia in spontaneous labor].
Pharmacodynamic and pharmacokinetic peculiarities of moradol have been studied during natural delivery. It has been shown that moradol injected both intramuscularly and intravenously in the first period of labour did not inhibit the circulation in the women in labour, had no impact on the course of labour and had no negative effect on the newborn. The use of moradol is recommended for analgesia of natural delivery. A correlation has been established between blood drug concentration and its pharmacodynamic indexes in women.
Kulakov
V I
VI
Proshina
I V
IV
Kozhakhmetov
A N
AN
Sariev
A K
AK
Zherdev
V P
VP
D000293:Adolescent; D000328:Adult; D000773:Anesthesia, Obstetrical; D002077:Butorphanol / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology; D004341:Drug Evaluation; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D007743:Labor, Obstetric / Q000187:drug effects / Q000502:physiology; D011247:Pregnancy; D013997:Time Factors
D002077:Butorphanol
Obosnovanie primeneniia moradola dlia obezbolivaniia samoproizvol'nykh rodov.