title: Lelystad virus, the cause of porcine epidemic abortion and respiratory syndrome: a review of mystery swine disease research at Lelystad.
abstract: This paper reviews the laboratory investigations that led us to isolate the Lelystad virus and demonstrate that this virus causes mystery swine disease. We describe: 1) isolating the virus from the disease; 2) characterizing the virus as a new enveloped RNA virus; 3) reproducing the disease experimentally with the isolated Lelystad virus; 4) isolating the virus from the experimentally induced disease.
authors: Central Veterinary Institute, Department of Virology, Lelystad, Netherlands.
authors: G
authors: G
authors: Wensvoort
authors: E P
authors: EP
authors: de Kluyver
authors: J M
authors: JM
authors: Pol
authors: F
authors: F
authors: Wagenaar
authors: R J
authors: RJ
authors: Moormann
authors: M M
authors: MM
authors: Hulst
authors: R
authors: R
authors: Bloemraad
authors: A
authors: A
authors: den Besten
authors: T
authors: T
authors: Zetstra
authors: C
authors: C
authors: Terpstra
mesh_terms: D000034:Abortion, Veterinary / Q000382:microbiology*; D000818:Animals; D002460:Cell Line; D002478:Cells, Cultured; D002642:Chick Embryo; D005260:Female; D011247:Pregnancy; D012328:RNA Viruses / Q000145:classification / Q000302:isolation & purification* / Q000502:physiology; D012141:Respiratory Tract Infections / Q000382:microbiology / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology*; D014777:Virus Diseases / Q000382:microbiology*