Serotonergic projections from the midbrain periaqueductal gray and nucleus raphe dorsalis to the nucleus parafascicularis of the thalamus.
By a double-labeling method combining the retrograde tracing of horseradish peroxidase and the immunocytochemical technique, serotonin-like immunoreactive neurons in the midbrain periaqueductal gray (PAG) and nucleus raphe dorsalis (DR) of the rat were observed to send projection fibers to the nucleus parafascicularis of the thalamus bilaterally with an ipsilateral dominance. These serotonin-containing projecting neurons were observed mainly at the middle-caudal levels of the ventrolateral subdivision of the PAG and less at the middle-rostral levels of the DR.
Chen
J
J
Department of Anatomy, 4th Military Medical University, Xi'an, Shaanxi, People's Republic of China.
Zeng
S L
SL
Rao
Z R
ZR
Shi
J W
JW
D000818:Animals; D006651:Histocytochemistry; D006735:Horseradish Peroxidase; D009475:Neurons, Afferent / Q000502:physiology; D010487:Periaqueductal Gray / Q000166:cytology / Q000502:physiology*; D011903:Raphe Nuclei / Q000166:cytology / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000276:immunology / Q000378:metabolism / Q000502:physiology*; D013787:Thalamic Nuclei / Q000166:cytology / Q000502:physiology*
D012701:Serotonin; D006735:Horseradish Peroxidase