Is risk for substance abuse unitary?
The hypothesis that risk for substance abuse is not unitary was tested by a log linear regression analysis. A series of risk factors was evaluated in a sample of 219 nonhospitalized, nontreated, young male and female subjects. Risk for alcohol abuse/dependence was independent of risk for drug abuse/dependence and the risks were additive in the prediction of lifetime substance abuse. Antisocial personality diagnosis predicted alcohol abuse/dependence, family history of drug abuse predicted drug abuse/dependence, and, additively, they predicted alcohol and drug abuse/dependence diagnosis over a lifetime. These data support a hypothesis that risk for substance abuse is not unitary.
Stabenau
J R
JR
Department of Psychiatry, University of Connecticut Health Center, Farmington 06030.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000437:Alcoholism / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics; D000987:Antisocial Personality Disorder / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics; D004522:Educational Status; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D016017:Odds Ratio; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D012044:Regression Analysis; D012307:Risk Factors; D012737:Sex Factors; D019966:Substance-Related Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics