title: Double-blind, controlled trial of short-term prednisone therapy in immunoglobulin A glomerulonephritis.
abstract: Twenty children and adolescents with IgA glomerulonephritis were enrolled in a crossover trial. Each received 12 weeks of prednisone therapy and 12 weeks of placebo dosing. Urinary protein and erythrocyte excretion were monitored during both courses. There was no evidence that, under the conditions of the study, corticosteroid therapy was effective in IgA nephropathy.
authors.affiliation: Department of Pediatrics, University of Cincinnati, Ohio.
authors.forename: T R
authors.initials: TR
authors.lastname: Welch
authors.forename: C
authors.initials: C
authors.lastname: Fryer
authors.forename: E
authors.initials: E
authors.lastname: Shely
authors.forename: D P
authors.initials: DP
authors.lastname: Witte
authors.forename: M
authors.initials: M
authors.lastname: Quinlan
mesh_terms: D000293:Adolescent; D002648:Child; D003404:Creatinine / Q000097:blood; D004311:Double-Blind Method; D005260:Female; D005922:Glomerulonephritis, IGA / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D006417:Hematuria / Q000209:etiology; D006801:Humans; D008297:Male; D011241:Prednisone / Q000627:therapeutic use*; D011507:Proteinuria / Q000209:etiology; D016896:Treatment Outcome
chemical_list: D003404:Creatinine; D011241:Prednisone