Intraocular penetration of rifampin in humans.
The penetration of rifampin into human aqueous humor was determined in 15 patients undergoing elective cataract surgery. Between 0.9 and 5.5 h after administration of a single 600-mg oral dose, concentrations ranged from 6.0 to 21.5 mg/liter in serum and from less than 0.2 to 1.3 mg/liter in aqueous humor.
Outman
W R
WR
Department of Pharmacy Services, Hartford Hospital, Connecticut 06115.
Levitz
R E
RE
Hill
D A
DA
Nightingale
C H
CH
D000284:Administration, Oral; D000368:Aged; D000369:Aged, 80 and over; D001082:Aqueous Humor / Q000737:chemistry*; D002387:Cataract Extraction; D006801:Humans; D012293:Rifampin / Q000097:blood / Q000737:chemistry*
D012293:Rifampin