title: Severity of aortic regurgitation: interstudy reproducibility of measurements with velocity-encoded cine MR imaging.
abstract: The interstudy reproducibility of velocity-encoded cine (VEC) magnetic resonance (MR) imaging for quantification of regurgitant volume (RV) and regurgitant fraction (RF) was studied in 10 patients with chronic aortic regurgitation. Each patient underwent two VEC MR imaging studies. RV and RF were measured on the aortic flow curve by quantifying antegrade and retrograde flow per cardiac cycle. VEC MR imaging measurements for RV and RF correlated closely with volumetric measurements for both studies (r greater than .97). Interstudy reproducibility for VEC MR imaging measurement of RV and RF was high (r greater than .97), and the interstudy variability for VEC MR imaging measurements was low. These results demonstrate a high accuracy of VEC MR imaging for measurement of RV and RF in patients with chronic aortic regurgitation. The level of interstudy reproducibility of VEC MR imaging for quantitative assessment of RV and RF indicates the potential of this technique for follow-up and monitoring of response to therapy.
authors.affiliation: Department of Radiology, University of California Medical School, San Francisco 94143.
authors.forename: M C
authors.initials: MC
authors.lastname: Dulce
authors.forename: G H
authors.initials: GH
authors.lastname: Mostbeck
authors.forename: M
authors.initials: M
authors.lastname: O'Sullivan
authors.forename: M
authors.initials: M
authors.lastname: Cheitlin
authors.forename: G R
authors.initials: GR
authors.lastname: Caputo
authors.forename: C B
authors.initials: CB
authors.lastname: Higgins
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001022:Aortic Valve Insufficiency / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D015203:Reproducibility of Results