Clinical features of systemic lupus erythematosus in Thai males and females.
From 1976 through 1988, 726 patients with systemic lupus erythematosus (SLE) were admitted to the Medical Service of Chulalongkorn Hospital, 666 cases (91.7%) being female and 60 cases (8.3%) male (the female-to-male ratio = 11:1). Clinical comparison of 60 males and 130 females (by randomized selection from the total of 666 females) was made. Onset of disease in males occurred later than in females (29.2 +/- 12.2 years vs 25.8 +/- 10.7 years, p less than 0.01). The majority of clinical manifestations were similar; however, musculoskeletal (63.3 vs 73.3%), cardiac manifestations (13.3 vs 26.1%) and Raynaud's phenomenon (18.3 vs 35.4%) were less common in males than females (p less than 0.01), whereas hematologic manifestations were more common in males than females (p less than 0.01).
Deesomchok
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Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Tumrasvin
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D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors