[Liver nuclear phospholipids of rats with varying thyroid status].
Thin-layer chromatography was used for fractionation of rat liver nuclear phospholipids after in vivo administration of 14C-sodium acetate. The administration of T3 to thyroidectomized rats caused a sharp increase in the incorporation of the label in all phospholipids of the nuclear fraction. The action of sphingomyelin and sphingomyelase on RNA-polymerase of nuclei isolated from the liver of thyroidectomized rats was tested. Sphingomyelin was shown to cause stimulation of RNA nuclear synthesis; parallel incubation with sphingomyelinase eliminated a stimulating effect of this phospholipid.
Umarova
G D
GD
Adylova
A T
AT
Ermakov
G N
GN
Atakhanova
B A
BA
D000818:Animals; D002467:Cell Nucleus / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D012321:DNA-Directed RNA Polymerases / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D008297:Male; D010743:Phospholipids / Q000378:metabolism*; D015138:RNA, Nuclear / Q000096:biosynthesis; D051381:Rats; D013108:Sphingomyelin Phosphodiesterase / Q000378:metabolism; D013109:Sphingomyelins / Q000494:pharmacology; D013961:Thyroid Gland / Q000502:physiology*; D014284:Triiodothyronine / Q000502:physiology*
D010743:Phospholipids; D015138:RNA, Nuclear; D013109:Sphingomyelins; D014284:Triiodothyronine; D012321:DNA-Directed RNA Polymerases; D013108:Sphingomyelin Phosphodiesterase
Fosfolipidy iader pecheni krys s razlichnym tireoidnym statusom.