Antibiotic-associated colitis and cystic fibrosis.
The use of antibiotics in patients with cystic fibrosis is widespread, and fecal carriage of Clostridium difficile occurs in up to 50% of these patients; however, antibiotic-associated colitis appears to be a rare occurrence. The reasons why this is so remain unknown. A case of antibiotic-associated colitis occurring in a patient with cystic fibrosis is described. Possible mechanisms for the rarity of antibiotic-associated colitis are reviewed and implications for prompt diagnosis and therapy are discussed.
Pokorny
C S
CS
A.W. Morrow Gastroenterology and Liver Centre, Royal Prince Alfred Hospital, Camperdown, N.S.W., Australia.
Bye
P T
PT
MacLeod
C
C
Selby
W S
WS
D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use; D016360:Clostridioides difficile / Q000302:isolation & purification; D003550:Cystic Fibrosis / Q000150:complications* / Q000382:microbiology; D004761:Enterocolitis, Pseudomembranous / Q000139:chemically induced / Q000150:complications*; D006801:Humans; D008297:Male; D011552:Pseudomonas Infections / Q000150:complications / Q000188:drug therapy
D000900:Anti-Bacterial Agents