title: Perception of bronchoconstriction in chronic asthma.
abstract: Twenty-nine asthmatic children were studied to assess their ability to detect the severity of their bronchoconstriction. First (STEP 0): each child was asked if he "felt asthma," inviting him to give a self-estimated obstruction score (SEOS) from 0 (no asthma) to 3 (severe asthma) and a baseline FEV1 was recorded. Then (STEP 1): methacholine was administered to all except 9 children with an FEV1 less than 80% of predicted who received saline nebulization and a second SEOS was recorded. Finally: salbutamol aerosol was administered and a third SEOS and FEV1 were obtained (STEP 2). Spearman's correlation coefficients r between SEOS and FEV1 were for the overall population -0.602, -0.517, and -0.104 at STEP 0, STEP 1, and STEP 2, respectively. The r values reduction during the trial can be due either to a decrease of children's concentration during the study or to a real difficulty in recognizing repeated changes in airway status. Some children tend to underestimate their bronchospasm. For these patients an accurate assessment of the severity of the bronchoconstriction requires an objective measurement during acute changes in asthmatic children.
authors.affiliation: Pediatric Department, University of Verona, Italy.
authors.forename: A L
authors.initials: AL
authors.lastname: Boner
authors.forename: G
authors.initials: G
authors.lastname: De Stefano
authors.forename: G L
authors.initials: GL
authors.lastname: Piacentini
authors.forename: C
authors.initials: C
authors.lastname: Bonizzato
authors.forename: L
authors.initials: L
authors.lastname: Sette
authors.forename: F
authors.initials: F
authors.lastname: Banfi
authors.forename: M C
authors.initials: MC
authors.lastname: Hindi-Alexander
mesh_terms: D000336:Aerosols; D000420:Albuterol / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy / Q000503:physiopathology / Q000523:psychology*; D016535:Bronchial Hyperreactivity / Q000503:physiopathology; D001985:Bronchial Provocation Tests; D002648:Child; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D016210:Methacholine Chloride; D010465:Perception / Q000502:physiology*
chemical_list: D000336:Aerosols; D016210:Methacholine Chloride; D000420:Albuterol