An office semiquantitative serum human chorionic gonadotropin determination.
OBJECTIVE
To compare the human chorionic gonadotropin (hCG) concentration, established by a standard serum quantitative hCG fluorescent immunoassay and a semiquantitative serum determination.


METHODS
Patients were asked to give two serum samples early in pregnancy to establish the accuracy of a semiquantitative serum hCG test in diluted and undiluted serum samples.


METHODS
In a laboratory setting, two serum samples were determined; one sample was submitted for standard serum hCG radioimmunoassay, and the other was tested for hCG by the 25 IU Tandem ICON Assay (Hybritech, Liege, Belgium) in diluted and undiluted serum samples.


METHODS
Sixteen patients supposed to be pregnant.


METHODS
Within dilutional zones, the results of a semiquantitative hCG test were compared with a known standard quantitative serum hCG immunoassay measurements.


RESULTS
The semiquantitative hCG ranges of serum hCG compare fairly well with an accurate standard quantitative serum hCG immunoassay.


CONCLUSIONS
The determination of a serum hCG range compares well with the standard quantitative serum hCG immunoassay (First International Reference Preparation) and can be completed within 15 minutes. This office semiquantitative serum hCG determination proved to be a quick and reliable test.
Kooi
S
S
Department of Gynecology and Obstetrics, Maria Hospital, Tilburg, The Netherlands.
Kock
H C
HC
D006063:Chorionic Gonadotropin / Q000097:blood*; D005260:Female; D015200:Fluoroimmunoassay; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D007124:Immunoenzyme Techniques; D011247:Pregnancy; D011863:Radioimmunoassay; D012016:Reference Values
D006063:Chorionic Gonadotropin