title: Effect of Ha-ras on mitogen-induced Ca(2+)- and K(+)-fluxes.
abstract: Transforming Ha-ras enhances the mitogen-induced activation of both the Ca(2+)-influx and the furosemide-sensitive Na+/K+/2Cl-cotransporter. Both systems represent essential early steps of mitogenic signal transduction in NIH 3T3 fibroblasts.
authors.affiliation: Institute of Medical Chemistry and Biochemistry, University of Innsbruck, Austria.
authors.forename: H
authors.initials: H
authors.lastname: Grunicke
authors.forename: K
authors.initials: K
authors.lastname: Maly
authors.forename: M
authors.initials: M
authors.lastname: Meyer
authors.forename: H
authors.initials: H
authors.lastname: Oberhuber
authors.forename: I
authors.initials: I
authors.lastname: Bichler
authors.forename: L S
authors.initials: LS
authors.lastname: Waldegger
authors.forename: E
authors.initials: E
authors.lastname: Woell
authors.forename: F
authors.initials: F
authors.lastname: Lang
mesh_terms: D016475:3T3 Cells; D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D001839:Bombesin / Q000494:pharmacology; D001920:Bradykinin / Q000494:pharmacology; D002118:Calcium / Q000378:metabolism*; D002455:Cell Division / Q000187:drug effects; D005347:Fibroblasts; D005665:Furosemide / Q000494:pharmacology; D051379:Mice; D008934:Mitogens / Q000494:pharmacology*; D015689:Oncogene Protein p21(ras) / Q000494:pharmacology*; D011188:Potassium / Q000378:metabolism*; D012413:Rubidium / Q000378:metabolism; D014162:Transfection
chemical_list: D008934:Mitogens; D005665:Furosemide; D015689:Oncogene Protein p21(ras); D012413:Rubidium; D001839:Bombesin; D011188:Potassium; D001920:Bradykinin; D002118:Calcium