Meningioma developed 25 years after radiation therapy for Cushing's disease.
A 44-year-old woman who had been therapeutically irradiated with 45 Gy to the sellar lesion for Cushing's disease has been in remission for 25 years. A large but asymptomatic brain tumor was accidentally found in the right middle fossa by a routine follow-up computed tomography. Upon surgical removal of the tumor, the histology revealed a fibroblastic meningioma. Although the incidence of meningioma following irradiation to pituitary adenoma is rare, a follow-up computed tomography should be taken to any possible late onset, and curable complication.
Tsukamoto
H
H
Second Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Yoshinari
M
M
Okamura
K
K
Ishitsuka
T
T
Fujishima
M
M
D000236:Adenoma / Q000532:radiotherapy; D000328:Adult; D003480:Cushing Syndrome / Q000532:radiotherapy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000209:etiology*; D008579:Meningioma / Q000175:diagnosis / Q000209:etiology*; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis / Q000209:etiology*; D016609:Neoplasms, Second Primary / Q000175:diagnosis / Q000209:etiology; D010911:Pituitary Neoplasms / Q000532:radiotherapy; D013997:Time Factors; D014057:Tomography, X-Ray Computed