title: The human BDNF gene maps between FSHB and HVBS1 at the boundary of 11p13-p14.
abstract: To map in detail the human gene for brain derived neurotrophic factor (BDNF) we have used a PCR-based assay to amplify the gene from somatic cell hybrids containing human chromosome 11 with deletion or translocation breakpoints in the WAGR region. The BDNF gene maps between the FSHB and HVBS1 loci, an interval of approximately 4 Mb at the boundary of 11p13 and 11p14.
authors.affiliation: MRC Human Genetics Unit, Western General Hospital, Edinburgh, United Kingdom.
authors.forename: I M
authors.initials: IM
authors.lastname: Hanson
authors.forename: A
authors.initials: A
authors.lastname: Seawright
authors.forename: V
authors.initials: V
authors.lastname: van Heyningen
mesh_terms: D001483:Base Sequence; D019208:Brain-Derived Neurotrophic Factor; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D002880:Chromosomes, Human, Pair 11; D004247:DNA; D004587:Electrophoresis, Agar Gel; D006801:Humans; D006822:Hybrid Cells; D008969:Molecular Sequence Data; D009414:Nerve Growth Factors / Q000235:genetics*; D009419:Nerve Tissue Proteins / Q000235:genetics*; D016133:Polymerase Chain Reaction
chemical_list: D019208:Brain-Derived Neurotrophic Factor; D009414:Nerve Growth Factors; D009419:Nerve Tissue Proteins; D004247:DNA