title: A (CA)n repeat polymorphism for the human skeletal muscle alpha-actinin gene ACTN2 and its localization on the linkage map of chromosome 1.
abstract: A CA dinucleotide repeat polymorphism has been identified for the skeletal muscle alpha-actinin gene ACTN2. The observed heterozygosity is 44% (predicted heterozygosity 50%, PIC 0.47). This polymorphic marker has been localized between D1S74 and D1S103 on the multipoint linkage map of chromosome 1 at a position 44.4 cM from the most distal marker D1S68 at 1 qter.
authors.affiliation: Genetics Division, Children's Hospital, Boston, Massachusetts 02115.
authors.forename: A H
authors.initials: AH
authors.lastname: Beggs
authors.forename: H A
authors.initials: HA
authors.lastname: Phillips
authors.forename: H
authors.initials: H
authors.lastname: Kozman
authors.forename: J C
authors.initials: JC
authors.lastname: Mulley
authors.forename: S D
authors.initials: SD
authors.lastname: Wilton
authors.forename: L M
authors.initials: LM
authors.lastname: Kunkel
authors.forename: N G
authors.initials: NG
authors.lastname: Laing
mesh_terms: D000185:Actinin / Q000235:genetics*; D001483:Base Sequence; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D004247:DNA; D008040:Genetic Linkage; D006579:Heterozygote; D006801:Humans; D008969:Molecular Sequence Data; D009132:Muscles / Q000378:metabolism*; D011110:Polymorphism, Genetic; D012091:Repetitive Sequences, Nucleic Acid
chemical_list: D000185:Actinin; D004247:DNA