Multicentricity in early breast cancer.
Breast preservation has focused attention on the extent and distribution of cancer in the breast. Recent studies suggest that there is spread from the primary tumor rather than a random distribution of cancer throughout the breast. As a result the term multicentric has largely been replaced by multifocal. Evidence that there is a geographic relationship of secondary deposits to the primary lesions opens the way to wide excision as definative treatment for selected patients with both invasive and in situ breast cancer.
Gump
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Department of Surgery, East Orange Veterans Administration Medical Center, NJ 07018.
D001943:Breast Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D015994:Incidence; D015412:Mastectomy, Segmental / Q000592:standards; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011878:Radiotherapy