title: Gastric adenocarcinoma simulating benign gastric ulcer.
abstract: The pathologic features and prognosis of patient in whom gastric cancer simulates at endoscopy as a benign gastric ulcer has been poorly characterized. We performed a retrospective study with particular reference to the long term prognosis on 191 patients treated for gastric adenocarcinoma over the period 1980-1986. In 176 of these 191 patients (92.2%), the endoscopic findings suggested cancers, while in the remaining 15 patients (7.8%), the endoscopic appearance suggested benign ulcer. Comparing gastric cancers masquerading as benign gastric ulcers with those appeared malignant endoscopically, the former had higher resectability rate (100% vs 77.3%), higher incidence of early gastric cancer (73.3% vs 6.25%), less poorly differentiated carcinoma (33.3% vs 65.4%), less lymph node metastasis (13% vs 69.5%) and a higher five-year survival rate (86.6% vs 24.8%) (p less than 0.05 in all). Our study indicated that gastric adenocarcinomas simulated benign gastric ulcers at endoscopy are mostly early gastric cancers that carry a much better prognosis.
authors.affiliation: Department of Hepato-Gastroenterology, Chang Gung Memorial Hospital, Taipei, Taiwan, R.O.C.
authors.forename: T O
authors.initials: TO
authors.lastname: Chan
authors.forename: Y C
authors.initials: YC
authors.lastname: Kuo
authors.forename: R N
authors.initials: RN
authors.lastname: Chien
authors.forename: I S
authors.initials: IS
authors.lastname: Sheen
authors.forename: D Y
authors.initials: DY
authors.lastname: Lin
authors.forename: C M
authors.initials: CM
authors.lastname: Chu
authors.forename: P C
authors.initials: PC
authors.lastname: Chen
authors.forename: C S
authors.initials: CS
authors.lastname: Wu
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D005260:Female; D005773:Gastroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000473:pathology; D013276:Stomach Ulcer / Q000175:diagnosis* / Q000473:pathology