title: Down syndrome: an otolaryngologic perspective.
abstract: The otolaryngologic manifestations of Down syndrome often masquerade as common and seemingly trivial conditions. Behind this facade lies a broad spectrum of disease which can detract from an inherently diminished level of function and jeopardize survival. This paper examines the pertinent associations between Down syndrome and various pathological entities related to the head and neck. Evaluation of current therapeutic modalities reinforces the need for early diagnosis and treatment so that the potential of this patient group is fulfilled.
authors.affiliation: Joint Center for Otolaryngology, Harvard Medical School, Boston, Mass.
authors.forename: S E
authors.initials: SE
authors.lastname: Strome
authors.forename: M
authors.initials: M
authors.lastname: Strome
mesh_terms: D004314:Down Syndrome / Q000150:complications*; D004427:Ear Diseases / Q000188:drug therapy / Q000209:etiology* / Q000628:therapy; D006311:Hearing Disorders / Q000209:etiology; D006801:Humans; D012891:Sleep Apnea Syndromes / Q000209:etiology* / Q000628:therapy