Intimal thickening in arterial autografts. Role of the adventitial layer.
In the present work, the repairing response of the iliac arterial wall is studied after carrying out autografts in segments of these vessels. The formation of the intimal hyperplasia, which occurred in all the cases, was followed at the biochemical level (tritium thymidine incorporation) and with light and electron microscopy. The adventitial layer showed great activity during the repairing process. We believe that it plays an important role not only in neoadventitial formation, but also in myointimal raising.
Buján
J
J
Department of Morphological Sciences and Surgery, Faculty of Medicine, University of Alcalá de Henares, Madrid, Spain.
Bellón
J M
JM
Gianonatti
M C
MC
Golitsin
A
A
D000818:Animals; D003238:Connective Tissue / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D004730:Endothelium, Vascular / Q000473:pathology* / Q000637:transplantation / Q000648:ultrastructure; D005260:Female; D006965:Hyperplasia / Q000473:pathology; D007083:Iliac Artery / Q000473:pathology* / Q000637:transplantation / Q000648:ultrastructure; D008954:Models, Biological; D051381:Rats; D011919:Rats, Inbred Strains; D014182:Transplantation, Autologous; D014945:Wound Healing