Neuroanatomic/neuropathologic correlates in schizophrenia.
In the 1980s, numerous studies demonstrated neuropathologic changes in schizophrenia. Increased ventricle-brain ratios in schizophrenics have been reported. Birth-related trauma coupled with a genetic predisposition may be involved in the increased ventricle-brain ratios and in the development of some forms of the illness. Probable embryogenic anomalies in the hippocampus and other informational processing centers seem involved.
Waldman
A J
AJ
Department of Psychiatry, College of Medicine, University of Florida, Gainesville.
D001921:Brain / Q000473:pathology*; D002531:Cerebellum / Q000473:pathology; D002540:Cerebral Cortex / Q000473:pathology; D002552:Cerebral Ventricles / Q000473:pathology; D005069:Evaluation Studies as Topic; D006801:Humans; D008032:Limbic System / Q000473:pathology; D008279:Magnetic Resonance Imaging; D009445:Neuroanatomy; D015995:Prevalence; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology*; D014057:Tomography, X-Ray Computed