[Dark and photosensitized hemolysis of erythrocytes in the presence of dithranol].
Ditranol (1,8-dihydroxy-9-antrone) induced dark lysis of erythrocytes. After irradiation of the cells with UV-light (366 nm UV-A light) in the presence of ditranol (DUVA-effect) the hemolytic effect increases. It has been found that antioxidant butylated hydroxytoluene BHT in the concentration 10(-7) M did not affect the dark lysis, while with increased BHT concentration up to 10(-5) M the hemolytic effect of ditranol was intensified. The presence of BHT in the above concentration under DUVA-effect did not change the velocity of cell lysis. Sodium aside did not affect the dark hemolysis of ditranol, but it inhibited photosensitized hemolysis.
Polev
A V
AV
Bezdetnaia
L N
LN
Akhtiamov
S N
SN
Vladimirov
V V
VV
Potapenko
A Ia
AIa
D000875:Anthralin / Q000494:pharmacology*; D001386:Azides / Q000494:pharmacology; D002084:Butylated Hydroxytoluene / Q000494:pharmacology; D004347:Drug Interactions; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000528:radiation effects*; D006461:Hemolysis / Q000187:drug effects / Q000528:radiation effects*; D006801:Humans; D019810:Sodium Azide; D014466:Ultraviolet Rays
D001386:Azides; D002084:Butylated Hydroxytoluene; D019810:Sodium Azide; D000875:Anthralin
Temnovoĭ i fotosensibilizirovannyĭ gemoliz éritrotsitov v prisutstvii ditranola.