[The growth modifying effect of wound ointments on cell cultures].
Ointments are often used for the treatment of wounds with impaired healing or for patients with severe burning. Therefore, some information about their pharmacological effects is necessary. This paper presents an in vitro model for testing the effects of ointments on an isolated cell type with the possibility of quantification. In this study fibroblasts of the human gums and 12 ointments available without prescription were used. To investigate the toxic effects, we examined the morphological changes and autoradiography. The results and their clinical implications are discussed.
Hauptmann
S
S
Institut für Pathologie, Rheinisch-Westfälischen Technischen Hochschule, Aachen.
Schäfer
H
H
Fritz
A
A
Hauptmann
P
P
D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects*; D002478:Cells, Cultured; D003879:Dermatologic Agents / Q000494:pharmacology*; D005347:Fibroblasts / Q000187:drug effects; D006801:Humans; D009824:Ointments; D014945:Wound Healing / Q000187:drug effects*
D000891:Anti-Infective Agents, Local; D003879:Dermatologic Agents; D009824:Ointments
Untersuchung der wachstumsbeeinflussenden Wirkung von Wundsalben an der Zellkultur.