title: P3 recordings in patients with bilateral temporal lobe lesions.
abstract: We recorded event-related potentials to an acoustic "oddball" paradigm from 19 scalp derivations in five patients (three women and two men; age range, 44 to 56) who had global amnesia following encephalitis. CT and MRI showed severe bilateral lesions of anterior and midtemporal lobes. A P3 component, with a peak latency within the normal limits for age-matched controls, was recorded to "target" stimuli in four patients from all leads except Fp1, Fp2, F7, F8, T3, and T4. In the fifth patient, the P3 peak was delayed.
authors.affiliation: Department of Neurology and Behavioral Sciences, State University of Chieti, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Onofrj
authors.forename: T
authors.initials: T
authors.lastname: Fulgente
authors.forename: D
authors.initials: D
authors.lastname: Nobilio
authors.forename: G
authors.initials: G
authors.lastname: Malatesta
authors.forename: S
authors.initials: S
authors.lastname: Bazzano
authors.forename: P
authors.initials: P
authors.lastname: Colamartino
authors.forename: D
authors.initials: D
authors.lastname: Gambi
mesh_terms: D000328:Adult; D000647:Amnesia / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D004660:Encephalitis / Q000150:complications; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D008032:Limbic System / Q000473:pathology / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013702:Temporal Lobe / Q000473:pathology / Q000503:physiopathology*