[Cicatricial mucous membrane pemphigoid with laryngeal involvement. Case report and review of the literature].
Benign mucous membrane pemphigoid (BMMP) is characterized by immunoglobulin deposits along the basal zone of the skin and mucous membranes, leading to blistering erosions of the involved regions. We report the case history of a 72-year old woman, in whom a cicatricial, supraglottic stenosis caused increasing dyspnea. Through immunohistochemical analysis the diagnosis of BMMP was confirmed. Therapy with cyclophosphamide and steroids led to a remission. Clinical, diagnostic and therapeutic aspects of this laryngologic-dermatologic disease are presented and discussed in the context of the available literature.
Wilhelm
T
T
HNO-Klinik, Medizinischen Hochschule Hannover.
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000368:Aged; D003520:Cyclophosphamide / Q000008:administration & dosage; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007070:Immunoglobulin A / Q000032:analysis; D007073:Immunoglobulin E / Q000032:analysis; D007818:Laryngeal Diseases / Q000188:drug therapy / Q000473:pathology*; D007830:Larynx / Q000473:pathology; D010390:Pemphigoid, Benign Mucous Membrane / Q000188:drug therapy / Q000473:pathology*
D000305:Adrenal Cortex Hormones; D007070:Immunoglobulin A; D007073:Immunoglobulin E; D003520:Cyclophosphamide
Vernarbendes Schleimhautpemphigoid mit laryngealer Beteiligung. Fallbericht und Literaturübersicht.