Lessons in prevention of ischemic heart disease learned from pathological studies of coronary atherosclerosis.
The recent status of the extent and severity of atherosclerosis in Japanese children and young adults and its causative factor are presented. The material and data are collected from 2,856 autopsies, with the age range of 1 month to 39 years. Fibrinogen-fibrin metabolism in the arterial wall has a definite role in atherogenesis. The incidence of myocardial infarction in 539 consecutive autopsy cases over 40 years old at Kyushu University is 12.7%.
Tanaka
K
K
Department of Pathology, Faculty of Medicine, Kyushu University, Japan.
Sueishi
K
K
D000293:Adolescent; D000328:Adult; D001011:Aorta / Q000473:pathology; D002536:Cerebral Arteries / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D003324:Coronary Artery Disease / Q000453:epidemiology / Q000473:pathology*; D003327:Coronary Disease / Q000453:epidemiology / Q000517:prevention & control*; D003331:Coronary Vessels / Q000378:metabolism / Q000473:pathology; D005260:Female; D005340:Fibrinogen / Q000378:metabolism; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007564:Japan / Q000453:epidemiology; D008297:Male; D015999:Multivariate Analysis
D005340:Fibrinogen