Role of rifampin and clofazimine ointments in the treatment of leprosy.
The use of rifampin and clofazimine ointments alone and in combination over the patches of tuberculoid patients had a beneficial effect. In combination (rifampin and clofazimine), erythema, inflammation, and edema are considerably reduced. For some of the cases with a recent appearance of a patch, the patch completely disappeared. It is suggested that topical therapy with rifampin and clofazimine ointments would be economical and beneficial in tuberculoid leprosy.
Venkateswarlu
B
B
Venkataramana
D
D
Rao
A V
AV
Prabhakar
M C
MC
Reddy
B M
BM
D002991:Clofazimine / Q000627:therapeutic use*; D003872:Dermatitis / Q000188:drug therapy; D004338:Drug Combinations; D004487:Edema / Q000188:drug therapy; D004890:Erythema / Q000188:drug therapy; D006801:Humans; D015441:Leprosy, Tuberculoid / Q000188:drug therapy*; D009824:Ointments; D012293:Rifampin / Q000627:therapeutic use*
D004338:Drug Combinations; D009824:Ointments; D002991:Clofazimine; D012293:Rifampin