title: [Dark and photosensitized hemolysis of erythrocytes in the presence of dithranol].
abstract: Ditranol (1,8-dihydroxy-9-antrone) induced dark lysis of erythrocytes. After irradiation of the cells with UV-light (366 nm UV-A light) in the presence of ditranol (DUVA-effect) the hemolytic effect increases. It has been found that antioxidant butylated hydroxytoluene BHT in the concentration 10(-7) M did not affect the dark lysis, while with increased BHT concentration up to 10(-5) M the hemolytic effect of ditranol was intensified. The presence of BHT in the above concentration under DUVA-effect did not change the velocity of cell lysis. Sodium aside did not affect the dark hemolysis of ditranol, but it inhibited photosensitized hemolysis.
authors.forename: A V
authors.initials: AV
authors.lastname: Polev
authors.forename: L N
authors.initials: LN
authors.lastname: Bezdetnaia
authors.forename: S N
authors.initials: SN
authors.lastname: Akhtiamov
authors.forename: V V
authors.initials: VV
authors.lastname: Vladimirov
authors.forename: A Ia
authors.initials: AIa
authors.lastname: Potapenko
mesh_terms: D000875:Anthralin / Q000494:pharmacology*; D001386:Azides / Q000494:pharmacology; D002084:Butylated Hydroxytoluene / Q000494:pharmacology; D004347:Drug Interactions; D004910:Erythrocyte Membrane / Q000187:drug effects / Q000528:radiation effects*; D006461:Hemolysis / Q000187:drug effects / Q000528:radiation effects*; D006801:Humans; D019810:Sodium Azide; D014466:Ultraviolet Rays
chemical_list: D001386:Azides; D002084:Butylated Hydroxytoluene; D019810:Sodium Azide; D000875:Anthralin
vernacular_title: Temnovoĭ i fotosensibilizirovannyĭ gemoliz éritrotsitov v prisutstvii ditranola.