title: [A case of hypertrophic pulmonary osteoarthropathy caused by adenocarcinoma of the lung].
abstract: A 58 year old housewife with tumor shadow in the right upper lung field on the chest X-ray was admitted. Marked swelling and severe arthralgia of both extremities and soft tissue clubbing of the fingers had been presented for two years prior to admission. The radiographs and bone scintigrams indicated proliferating periostitis along the long bones. Bronchofiberscope showed the obstruction of B2a of the right bronchus but the histological diagnosis was not established. Serum level of CEA and IAP were found to be high. Soon after the right upper lobectomy, arthralgia was significantly improved. The histological evaluation revealed a well differentiated adenocarcinoma of a primary lung cancer without mediastinal lymph node metastasis. Within 4 months the serum level of CEA and IAP normalized, the clubbing and the periosteal changes of the bones regressed.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Osakafu Mishima Critical Care Medical Center, Osaka, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Fukumoto
authors.forename: T
authors.initials: T
authors.lastname: Nishimoto
authors.forename: H
authors.initials: H
authors.lastname: Morita
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000601:surgery; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000601:surgery; D008875:Middle Aged; D010005:Osteoarthropathy, Secondary Hypertrophic / Q000209:etiology*; D010257:Paraneoplastic Syndromes / Q000209:etiology; D011013:Pneumonectomy