title: ABH-related antigens in human male genital tract. A histochemical examination.
abstract: The localization of ABH related antigens in human male reproductive tract was examined using monoclonal antibodies and an avidin biotin complex method. No positive reaction with blood group antibodies on spermatozoa was observed in testis and ductus epididymidis apart from erythrocytes and endothelial cells. The expression of ABH and ABH related antigens in ductuli efferents testis, ductus epididymidis, seminal vesicle and prostate was complexly coded by a combination of H, Se, Le and X genes. The results obtained in this study indicate that the ABH antigens detected on spermatozoa of seminal stains are coating antigens and not inherent to the cell membrane, and the ABO, H, Se, Le and X genes are subjected to a tissue-dependent differential expression.
authors.affiliation: Department of Legal Medicine, Shiga University of Medical Science, Ohtsu, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Nishi
authors.forename: T
authors.initials: T
authors.lastname: Fukunaga
authors.forename: Y
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: M
authors.initials: M
authors.lastname: Yamada
authors.forename: M
authors.initials: M
authors.lastname: Kane
authors.forename: A
authors.initials: A
authors.lastname: Tanegashima
authors.forename: S
authors.initials: S
authors.lastname: Rand
authors.forename: B
authors.initials: B
authors.lastname: Brinkmann
mesh_terms: D000017:ABO Blood-Group System / Q000235:genetics / Q000276:immunology*; D000911:Antibodies, Monoclonal; D001360:Avidin; D001710:Biotin; D005069:Evaluation Studies as Topic; D005554:Forensic Medicine / Q000379:methods*; D015870:Gene Expression; D005837:Genitalia, Male / Q000033:anatomy & histology*; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods*; D007519:Isoantigens / Q000032:analysis*; D008297:Male
chemical_list: D000017:ABO Blood-Group System; D000911:Antibodies, Monoclonal; D007519:Isoantigens; D001360:Avidin; D001710:Biotin