Retrospective approach to explain growth retardation and urolithiasis in a child with long-term nutritional acid loading.
An infant with phenylketonuria unintentionally received a highly acidic low phenylalanine diet for 29 months. Temporary growth retardation and urolithiasis were observed, probably as direct effects of chronic acid loading. Caries at the age of 6 years may be a late consequence. This case report shows that chronic dietary acid load may cause serious side effects.
Manz
F
F
Forschungsinstitut für Kinderernährung, Dortmund.
Schmidt
H
H
D000136:Acid-Base Equilibrium; D003731:Dental Caries / Q000209:etiology; D004032:Diet / Q000009:adverse effects*; D005260:Female; D006130:Growth Disorders / Q000209:etiology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn; D007668:Kidney / Q000502:physiology; D010661:Phenylketonurias / Q000150:complications* / Q000178:diet therapy; D012189:Retrospective Studies; D014545:Urinary Calculi / Q000209:etiology*