Preimplantation genetic analysis.
Advanced reproductive technologies have afforded us access to human preembryos, allowing the possibility of preimplantation genetic diagnosis of certain genetic diseases. This paper thoroughly reviews both the micro-manipulation and molecular biologic aspects of this new and exciting branch of medicine. In addition, some of the moral and ethical considerations relating to preembryo genetic diagnosis are discussed.
Kaufmann
R A
RA
Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk 23510.
Morsy
M
M
Takeuchi
K
K
Hodgen
G D
GD
D001706:Biopsy; D015925:Cryopreservation / Q000379:methods / Q000592:standards; D004247:DNA; D047108:Embryonic Development; D004992:Ethics, Medical; D005260:Female; D005307:Fertilization in Vitro; D005820:Genetic Testing / Q000379:methods* / Q000592:standards; D006801:Humans; D009693:Nucleic Acid Hybridization; D015345:Oligonucleotide Probes; D016133:Polymerase Chain Reaction; D011247:Pregnancy
D015345:Oligonucleotide Probes; D004247:DNA