title: Megavoltage grid total body irradiation of C3Hf/SED mice.
abstract: The effect of a grid on whole-body megavoltage radiation tolerance in C3Hf/SED mice was studied. Adult mice were irradiated beneath a 50% megavoltage grid. LD50 (50% lethality) values were measured at ten and 30 days. LD50/30 day increased by a factor of 1.5 for mice receiving both single and two fraction irradiation beneath the grid. LD50/ten day increased by factors of 1.1 to 1.2 for single, two, and five fraction irradiation beneath the grid.
authors.affiliation: Department of Radiation Medicine, University of Kentucky Medical Center.
authors.forename: R C
authors.initials: RC
authors.lastname: Miller
authors.forename: K G
authors.initials: KG
authors.lastname: Wilson
authors.forename: J M
authors.initials: JM
authors.lastname: Feola
authors.forename: M
authors.initials: M
authors.lastname: Urano
authors.forename: R J
authors.initials: RJ
authors.lastname: Yaes
authors.forename: P
authors.initials: P
authors.lastname: McLaughlin
authors.forename: Y
authors.initials: Y
authors.lastname: Maruyama
mesh_terms: D000818:Animals; D003037:Cobalt Radioisotopes; D004307:Dose-Response Relationship, Radiation; D007928:Lethal Dose 50; D051379:Mice; D008809:Mice, Inbred C3H / Q000502:physiology*; D011836:Radiation Tolerance; D011882:Radiotherapy, High-Energy / Q000295:instrumentation* / Q000379:methods; D013997:Time Factors; D014916:Whole-Body Irradiation / Q000295:instrumentation* / Q000379:methods
chemical_list: D003037:Cobalt Radioisotopes