Regulation of lung inflammation by local glucocorticoid metabolism: an hypothesis.
Schleimer
R P
RP
Johns Hopkins Asthma and Allergy Center, Department of Medicine, Baltimore, Maryland 21224.
Kato
M
M
D042842:11-beta-Hydroxysteroid Dehydrogenases; D000287:Administration, Topical; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000378:metabolism*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000378:metabolism* / Q000494:pharmacology; D001249:Asthma / Q000188:drug therapy; D002229:Carbenoxolone / Q000494:pharmacology; D005333:Fetus / Q000378:metabolism; D005938:Glucocorticoids / Q000378:metabolism*; D006034:Glycyrrhetinic Acid / Q000031:analogs & derivatives / Q000494:pharmacology; D019695:Glycyrrhizic Acid; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism; D006913:Hydroxysteroid Dehydrogenases / Q000037:antagonists & inhibitors / Q000502:physiology*; D007668:Kidney / Q000378:metabolism; D008168:Lung / Q000378:metabolism*
D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D005938:Glucocorticoids; D019695:Glycyrrhizic Acid; D006913:Hydroxysteroid Dehydrogenases; D042842:11-beta-Hydroxysteroid Dehydrogenases; D002229:Carbenoxolone; D006034:Glycyrrhetinic Acid; D006854:Hydrocortisone