Effect of androsole acetate on blood pressure of stress-sensitive hypertensive rats.
The basal and stress-induced blood pressure was found to decrease in rats with inherited stress sensitive hypertension (SSHR) followed by androzole acetate administration orally (30 mg/kg body weight) for eight days. The basal levels of arterial blood pressure was decreased by 17.5% and that of stress-induced animals--by 19%.
Leotsakos
A
A
St. Mary's Hospital Medical School, London.
Kotlobay
A A
AA
Kamernitski
A V
AV
Boldyrev
A A
AA
D000818:Animals; D000959:Antihypertensive Agents / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects*; D006973:Hypertension / Q000209:etiology / Q000503:physiopathology; D008297:Male; D051381:Rats; D011918:Rats, Inbred SHR; D013256:Steroids / Q000494:pharmacology*; D013312:Stress, Physiological / Q000150:complications
D000959:Antihypertensive Agents; D013256:Steroids