title: Spatial attention in HIV-1 infection: a preliminary report.
abstract: In a preliminary study, 30 nondemented human immunodeficiency virus (HIV-1) seropositive subjects without acquired immunodeficiency syndrome and 14 seronegative controls performed a reaction time measure of spatial attention. Compared with controls, seropositive asymptomatic subjects showed normal facilitation of reaction time at short cue-target intervals when attention was precued, but symptomatic subjects were impaired. However, asymptomatic subjects showed no evidence of normal inhibition of attention at the cued location at longer cue-target intervals, suggesting possible subtler spatial attentional deficits in this group. Cognitive slowing in HIV-1 infection may have an attentional component, with possible involvement of both automatic and controlled processes.
authors.affiliation: Department of Neurology, University of California, Davis.
authors.forename: E M
authors.initials: EM
authors.lastname: Martin
authors.forename: D J
authors.initials: DJ
authors.lastname: Sorensen
authors.forename: L C
authors.initials: LC
authors.lastname: Robertson
authors.forename: H E
authors.initials: HE
authors.lastname: Edelstein
authors.forename: V A
authors.initials: VA
authors.lastname: Chirurgi
mesh_terms: D015526:AIDS Dementia Complex / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D000328:Adult; D001288:Attention / Q000502:physiology*; D006679:HIV Seropositivity / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D015497:HIV-1 / Q000472:pathogenicity*; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D009949:Orientation / Q000502:physiology*; D010364:Pattern Recognition, Visual / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology