title: Erythema elevatum diutinum: a clinicopathological study.
abstract: Erythema elevatum diutinum is a syndrome of vasculitis in which lesions, typically over the extensor surfaces, showed a mixed inflammatory infiltrate on biopsy. We describe a series of 13 patients. The most common association in our series was with hypergammaglobulinemia; both mono and polyclonal. Chronic infection, not streptococcal, was a less frequent finding although two of three patients had a positive reaction to the intradermal injection of streptococcal antigen. Dapsone remains the initial treatment of choice.
authors.affiliation: Department of Dermatology, North Staffordshire Hospital Centre, Stoke-on-Trent, U.K.
authors.forename: S M
authors.initials: SM
authors.lastname: Wilkinson
authors.forename: J S
authors.initials: JS
authors.lastname: English
authors.forename: N P
authors.initials: NP
authors.lastname: Smith
authors.forename: E
authors.initials: E
authors.lastname: Wilson-Jones
authors.forename: R K
authors.initials: RK
authors.lastname: Winkelmann
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002675:Child, Preschool; D004890:Erythema / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000473:pathology*; D014657:Vasculitis / Q000473:pathology
chemical_list: D007136:Immunoglobulins