[Gluten enteropathy].
The authors relate the results of 10 years of observations of 113 patients suffering from gluten enteropathy (GE) of the adults. In all the patients, the diagnosis was supported by the presence of hyper-regenerative atrophy of the small intestinal mucosa (total in 70% and subtotal in 30%). Metabolic disorders and cellular immunity were investigated. At the onset of the observations 70.7% of the patients demonstrated malabsorption, stage III gravity, and 29.3% stage II. It has been proved that permanent and strict adherence to the agluten diet and administration of corticosteroids in the most severe cases in combination with pathogenetic therapy of diarrhea and metabolic disorders permit attaining a steady clinical remission, improvement of normalization of the biochemical and immunological characteristics, a tendency toward normalization of the small intestinal mucosa, and even the recovery of its normal structure in part of the cases.
Parfenov
A I
AI
Krums
L M
LM
Ekisenina
N I
NI
Gudkova
R B
RB
Sivash
E S
ES
Chikunova
B Z
BZ
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002446:Celiac Disease / Q000145:classification / Q000175:diagnosis / Q000178:diet therapy / Q000209:etiology*; D002648:Child; D003131:Combined Modality Therapy; D003967:Diarrhea / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D007421:Intestine, Small / Q000000981:diagnostic imaging / Q000473:pathology; D008875:Middle Aged; D011859:Radiography
Glutenovaia énteropatiia.