title: Multicentricity in early breast cancer.
abstract: Breast preservation has focused attention on the extent and distribution of cancer in the breast. Recent studies suggest that there is spread from the primary tumor rather than a random distribution of cancer throughout the breast. As a result the term multicentric has largely been replaced by multifocal. Evidence that there is a geographic relationship of secondary deposits to the primary lesions opens the way to wide excision as definative treatment for selected patients with both invasive and in situ breast cancer.
authors.affiliation: Department of Surgery, East Orange Veterans Administration Medical Center, NJ 07018.
authors.forename: F E
authors.initials: FE
authors.lastname: Gump
mesh_terms: D001943:Breast Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D015994:Incidence; D015412:Mastectomy, Segmental / Q000592:standards; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011878:Radiotherapy