[Influence of novodrin and obsidan on the secretory activity of tissue basophils of the thyroid and parathyroid glands].
The task was to investigate secretory activity of sets of tissue basophils of the thyroid and parathyroids during administration of isoproterenol (novodrin) and propranolol (obsidan); 32 rats, divided into 2 groups, were given a single intraperitoneal injection of 20 mg of isoproterenol (the 1 st group) and 2.5. mg of propranolol (the 2nd group) with their subsequent decapitation with a 12-minute interval for 3 h. Six rats were controls. Increased tissue activity of tissue basophils was noted and interpreted as a result of elevated secretion of calcium regulating hormones developing under the influence of beta-adrenergic drugs.
Pavlov
A B
AB
Miro
T L
TL
D000818:Animals; D015549:Basophil Degranulation Test; D001491:Basophils / Q000187:drug effects* / Q000378:metabolism; D007545:Isoproterenol / Q000494:pharmacology*; D008297:Male; D010280:Parathyroid Glands / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D011433:Propranolol / Q000494:pharmacology*; D051381:Rats; D012636:Secretory Rate / Q000187:drug effects; D013961:Thyroid Gland / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism
D011433:Propranolol; D007545:Isoproterenol
Vliianie novodrina i obzidana na sekretornuiu aktivnost' tkanevykh bazofilov shchitovidnoĭ i okoloshchitovidnykh zhelez.