title: Magnetic resonance microscopy of rabbit eyes.
abstract: Magnetic resonance (MR) micro-imaging was performed on enucleated eyes from rabbits previously injected with perfluoropropane gas (C3F8), with or without the surgical creation of retinal detachment. Condensed vitreous, which exhibited shortened longitudinal relaxation time (T1), could be differentiated with proton-density and T1-weighted imaging. Gradient-echo imaging could in addition detect vitreo-retinal tractions. The detached retina itself was also seen. Further, proton-density but not T1-weighted imaging showed lens opacities appearing as high-intensity regions. MR microscopy is a convenient method for gross morphological examination of intact eyes.
authors.affiliation: Howe Laboratory of Ophthalmology, Harvard Medical School, Boston, MA 02114.
authors.forename: A
authors.initials: A
authors.lastname: Yoshida
authors.forename: K K
authors.initials: KK
authors.lastname: Kwong
authors.forename: C
authors.initials: C
authors.lastname: Chang
authors.forename: K
authors.initials: K
authors.lastname: Karino
authors.forename: T
authors.initials: T
authors.lastname: Iwasaki
authors.forename: S M
authors.initials: SM
authors.lastname: Buzney
authors.forename: J W
authors.initials: JW
authors.lastname: McMeel
authors.forename: H M
authors.initials: HM
authors.lastname: Cheng
mesh_terms: D000818:Animals; D002386:Cataract / Q000473:pathology; D005123:Eye / Q000473:pathology*; D005260:Female; D005466:Fluorocarbons; D007908:Lens, Crystalline / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D011817:Rabbits; D012163:Retinal Detachment / Q000473:pathology; D014822:Vitreous Body / Q000473:pathology
chemical_list: D005466:Fluorocarbons; C042852:perflutren