title: Polymorphism of coagulation factor XIII B subunit: further occurrence of FXIIIB*15 in Japanese and phenotyping in bloodstains.
abstract: The polymorphism of FXIIIB was investigated in 555 unrelated Japanese individuals using isoelectric focusing and immunoblotting. Five common phenotypes and a rare variant type FXIIIB 15-3 were observed. The allele frequencies were FXIIIB*1 = 0.3063, FXIIIB*2 = 0.0162, FXIIIB*3 = 0.6766 and FXIIIB*15 = 0.0009. Phenotyping was also possible from bloodstains stored at 37 degrees C for up to 4 months and from bloodstains stored at room temperature and at 4 degrees C for over 6 months. The FXIIIB system can provide a new powerful genetic marker for the medicolegal grouping of bloodstains.
authors.affiliation: Department of Legal Medicine, Yamanashi Medical University, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Komatsu
authors.forename: A
authors.initials: A
authors.lastname: Kido
authors.forename: Y
authors.initials: Y
authors.lastname: Kimura
authors.forename: M
authors.initials: M
authors.lastname: Oya
authors.forename: Y
authors.initials: Y
authors.lastname: Dobashi
authors.forename: K
authors.initials: K
authors.lastname: Hashimoto
mesh_terms: D000483:Alleles; D001801:Blood Stains; D005176:Factor XIII / Q000235:genetics*; D005828:Genetics, Population; D006801:Humans; D007525:Isoelectric Focusing; D007564:Japan; D010641:Phenotype; D011110:Polymorphism, Genetic / Q000235:genetics*
chemical_list: D005176:Factor XIII; C054380:factor XIIIb