title: A computer model of the kidney.
abstract: We developed a computer model of renal function that factors perfusion pressure, serum sodium, potassium, antidiuretic hormone and aldosterone concentrations to derive urine output, urinary sodium and urinary potassium excretion. The model implements Uttamsingh's (Uttamsingh, R.J., et al. Mathematical model of the human renal system. Med. Biol. Eng. Comput. 23 (1985) 525-536) analytical equations as an electrical circuit suitable for network analysis. This model is useful for studying the effects of renal blood flow and the humoral milieu on renal function in normal kidneys either as a stand-alone unit or in combination with other physiological electrical models.
authors.affiliation: Department of Surgery, Irvine Medical Center, University of California.
authors.forename: L J
authors.initials: LJ
authors.lastname: Goldstein
authors.forename: E B
authors.initials: EB
authors.lastname: Rypins
mesh_terms: D003198:Computer Simulation; D006801:Humans; D007668:Kidney / Q000502:physiology*; D008954:Models, Biological; D011188:Potassium / Q000652:urine; D011312:Pressure; D012016:Reference Values; D012964:Sodium / Q000652:urine; D012985:Software Design
chemical_list: D012964:Sodium; D011188:Potassium