title: Mersacidin, a new antibiotic from Bacillus. Fermentation, isolation, purification and chemical characterization.
abstract: Mersacidin (1) is a new peptide antibiotic containing beta-methyllanthionine. It is classified as a member of the proposed lantibiotic group of antibiotics, and is produced by a species of Bacillus. Mersacidin has a molecular weight of 1,824 (C80H120N20O21S4). The antibiotic is active against Gram-positive organisms including methicillin-resistant Staphylococcus aureus, but has no activity against Gram-negative bacteria or fungi.
authors.affiliation: Microbiology Department, Hoechst India Limited, Mulund, Bombay.
authors.forename: S
authors.initials: S
authors.lastname: Chatterjee
authors.forename: S
authors.initials: S
authors.lastname: Chatterjee
authors.forename: S J
authors.initials: SJ
authors.lastname: Lad
authors.forename: M S
authors.initials: MS
authors.lastname: Phansalkar
authors.forename: R H
authors.initials: RH
authors.lastname: Rupp
authors.forename: B N
authors.initials: BN
authors.lastname: Ganguli
authors.forename: H W
authors.initials: HW
authors.lastname: Fehlhaber
authors.forename: H
authors.initials: H
authors.lastname: Kogler
mesh_terms: D000900:Anti-Bacterial Agents / Q000096:biosynthesis / Q000302:isolation & purification* / Q000494:pharmacology; D001407:Bacillus / Q000378:metabolism*; D001430:Bacteriocins; D005285:Fermentation; D010452:Peptide Biosynthesis; D010455:Peptides / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D001430:Bacteriocins; D010455:Peptides; C069959:mersacidin