title: Usefulness of perioperative pulsed Doppler flowmetry in predicting postoperative local ischemic complications after ileocolic esophagoplasty.
abstract: Regional ischemia may induce cervical anastomosis leakage or stenosis or graft necrosis after esophageal reconstruction by retrosternal interposition of an ileocolic graft. These complications may be related to systemic or local hemodynamic alterations. This study was designed to evaluate the relationship between immediate postoperative arterial blood supply to the graft, arterial patency monitored by angiography, and clinical outcome. Eight patients (mean age 30 +/- 4 years; standard deviation) were studied. Miniaturized Doppler implantable microprobes were sutured to the single artery supplying the graft and connected to an 8 MHz pulsed Doppler flowmeter. Systemic hemodynamic parameters and mesenteric hemodynamic data were collected 3 hours after the end of the surgical procedure. These data were compared with the angiogram of the right superior colic artery supplying the graft, systematically performed on the fifteenth postoperative day, and with the clinical course of follow-up for 3 months. Five patients (group 1) had excellent clinical and angiographic results. Mean mesenteric blood flow in these patients was 51 +/- 49 ml.min-1 (+/- standard deviation, ranging from 9 to 122). Three patients (group 2) had a poor clinical outcome. One had early complete graft necrosis and the two others had leakage of the cervical anastomosis with poor distal arterial vascularization of the graft on the angiogram. Mean mesenteric blood flow was nul in the first patient and, respectively, 24 and 28 ml.min-1 in the two others. Cardiac output and mean arterial pressure were in the same range for all patients. Phasic velocity shape analysis revealed that the three group 2 patients had an end-systolic or end-diastolic reverse flow pattern that was not observed in the five group 1 patients, which suggested a submaximal increase in downstream vascular resistance. This reverse flow pattern seems to be a good predictor of ischemia-related complications. We conclude that perioperative pulsed Doppler blood flow monitoring in an ileocolic graft may be useful for the diagnosis and prevention of ischemic complications.
authors.affiliation: Department of Anesthesiology, Hôpital Universitaire Saint-Louis, Paris, France.
authors.forename: L
authors.initials: L
authors.lastname: Jacob
authors.forename: O
authors.initials: O
authors.lastname: Rabary
authors.forename: S
authors.initials: S
authors.lastname: Boudaoud
authors.forename: D
authors.initials: D
authors.lastname: Payen
authors.forename: E
authors.initials: E
authors.lastname: Sarfati
authors.forename: D
authors.initials: D
authors.lastname: Gossot
authors.forename: E
authors.initials: E
authors.lastname: Rolland
authors.forename: B
authors.initials: B
authors.lastname: Eurin
authors.forename: M
authors.initials: M
authors.lastname: Celerier
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology; D002057:Burns, Chemical / Q000601:surgery; D002424:Caustics / Q000009:adverse effects; D003106:Colon / Q000601:surgery; D004940:Esophageal Stenosis / Q000139:chemically induced / Q000601:surgery; D004944:Esophagoplasty / Q000379:methods*; D006801:Humans; D007082:Ileum / Q000601:surgery; D007511:Ischemia / Q000000981:diagnostic imaging* / Q000453:epidemiology; D011183:Postoperative Complications / Q000000981:diagnostic imaging* / Q000453:epidemiology; D011237:Predictive Value of Tests; D019736:Prostheses and Implants; D013152:Splanchnic Circulation / Q000502:physiology; D014463:Ultrasonography
chemical_list: D002424:Caustics