title: Peters' anomaly and combination with other malformations (series of 16 patients).
abstract: A series of 15 patients with Peters' anomaly observed from 1987-1991 and a patient showing Wolf-Hirschhorn syndrome were studied retrospectively. Combined ocular anomalies were: microphthalmos (9x), myopia (4x), aniridia (2x), cataract (2x). Five of the patients had combined general anomalies: mental retardation, deafness, cardiac malformation (ASD II), and luxatio coxae. In two of them chromosomal anomalies were found: 4p minus syndrome, mosaic trisomy 9. After comparison of these data with those known from the literature the author confirms that Peters' anomaly is a morphologic finding rather than a distinct entity. Treatment depends on individual histopathologic findings and on the psychophysical development of the child.
authors.affiliation: University Eye Clinic Erlangen-Nürnberg, Germany.
authors.forename: U M
authors.initials: UM
authors.lastname: Mayer
mesh_terms: D000015:Abnormalities, Multiple / Q000235:genetics; D000328:Adult; D000869:Anterior Eye Segment / Q000002:abnormalities*; D002648:Child; D002675:Child, Preschool; D003318:Corneal Opacity / Q000150:complications; D005124:Eye Abnormalities / Q000150:complications / Q000235:genetics; D006801:Humans; D007223:Infant; D012189:Retrospective Studies