title: [Prospective course of therapy arresting attacks of atrial fibrillation in patients with preexcitation syndromes].
abstract: A comparative study of antiarrhythmic drugs was performed in 81 patients with atrial fibrillation attacks in the presence of preexcitation syndrome. The first intravenous administration of cordarone was effective in 84.06%, disopyramide--in 69%, ajmaline in 44.8, verapamil in 42.1, novocaine amide in 39.4 and ethacizin in 38.5% of the patients. The first oral administration of quinidine and kinilentin arrested 80.4% of arrhythmia attacks, disopyramide 66.7% propranolol and mexitil 37.5 and 33.3%, respectively. Prospective evolution of antiarrhythmic therapy manifested with decreased therapeutic efficacy of the drugs from 55.7 to 26.2% in the whole group during the period of 1-5 years.
authors.forename: I G
authors.initials: IG
authors.lastname: Fomina
authors.forename: V V
authors.initials: VV
authors.lastname: Iankin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000404:Ajmaline / Q000627:therapeutic use; D000638:Amiodarone / Q000627:therapeutic use; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000188:drug therapy*; D004206:Disopyramide / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008801:Mexiletine / Q000627:therapeutic use; D008875:Middle Aged; D016293:Moricizine / Q000031:analogs & derivatives / Q000627:therapeutic use; D011226:Pre-Excitation Syndromes / Q000150:complications*; D011342:Procainamide / Q000627:therapeutic use; D011433:Propranolol / Q000627:therapeutic use; D011802:Quinidine / Q000627:therapeutic use; D013997:Time Factors; D014700:Verapamil / Q000627:therapeutic use
chemical_list: D000889:Anti-Arrhythmia Agents; C027240:diethylamino-ethmozine; D000404:Ajmaline; D008801:Mexiletine; D016293:Moricizine; C009764:quinidine bisulfate; D011433:Propranolol; D014700:Verapamil; D004206:Disopyramide; D011802:Quinidine; D011342:Procainamide; D000638:Amiodarone
vernacular_title: Prospektivnaia évoliutsiia kupiruiushcheĭ terapii pri pristupakh mertsiatel'noĭ aritmii u bol'nykh s sindromom prezhdevremennogo vozbuzhdeniia zheludochkov.