Effect of pH on the stability of type-C toxin of Clostridium botulinum.
Stability of type-C botulinum toxin at pH 1.8-12.0 and during exposure to 5 and 28 degrees C for 20 and 16 h, respectively, was tested by titration on adult mice. The toxin was found in the samples kept at pH of 2.7-10.2, whereas, at the pH extremes of 1.8 and 12.0, it was inactivated.
Halouzka
J
J
Institute of Systematic and Ecological Biology, Czechoslovak Academy of Sciences, Brno.
Hubálek
Z
Z
D000818:Animals; D001905:Botulinum Toxins / Q000737:chemistry* / Q000633:toxicity; D001906:Botulism / Q000382:microbiology*; D006863:Hydrogen-Ion Concentration; D051379:Mice
D001905:Botulinum Toxins