title: Cervico-medullary junction hemangioblastomas. Report of two cases and review of the literature.
abstract: Reporting two cases of dorsally located cervico-medullary hemangioblastomas the Authors discuss clinico-biological features, diagnosis and therapy of this vascular neoplasms, analyzing the cases reported in detail in the available literature. In this site the tumor has often an exophitic development, adhering more or less extensively to the posterior surface of medulla oblungata, where progressively creates a niche. Transient neurogenic arterial blood hypertension, by possible involvement of the dorsal nucleus of vagal nerve, together with the lack of postoperative respiratory disturbances constitute the main clinical features of differentiation with intraaxial hemangioblastomas of the brainstem. Actually MRI represents the radiological investigation of choice, even if angiography still plays an important role in the correct preoperative diagnosis of hemangioblastomas. The therapy of dorsally located cervico-medullary hemangioblastomas is the total removal of the lesion also in asymptomatic patients, being the late surgical results generally successful.
authors.affiliation: Department of Neurological Sciences, University of Rome La Sapienza.
authors.forename: L
authors.initials: L
authors.lastname: Ferrante
authors.forename: L
authors.initials: L
authors.lastname: Mastronardi
authors.forename: M
authors.initials: M
authors.lastname: Acqui
authors.forename: P
authors.initials: P
authors.lastname: Missori
authors.forename: L
authors.initials: L
authors.lastname: Tacconi
authors.forename: A
authors.initials: A
authors.lastname: Fortuna
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000473:pathology*; D001933:Brain Stem / Q000473:pathology*; D005260:Female; D006394:Hemangiosarcoma / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D016896:Treatment Outcome