title: Effects of chewing gums sweetened with sorbitol or a sorbitol/xylitol mixture on the remineralisation of human enamel lesions in situ.
abstract: Intra-oral remineralisation of experimental caries-like lesions in human enamel, as determined by polarised light microscopy and quantitative microradiography, was promoted to a similar extent (% fall in delta Z, 18.6 and 19.0) by chewing a sorbitol or sorbitol/xylitol (3:1)-sweetened gum for 20 min after each of three meals and two sugary snacks daily. The results suggest that reported differences in the properties of the two sweeteners do not affect their ability to enhance remineralisation due to salivary stimulation.
authors.affiliation: Department of Clinical Dental Sciences, University of Liverpool, UK.
authors.forename: R H
authors.initials: RH
authors.lastname: Manning
authors.forename: W M
authors.initials: WM
authors.lastname: Edgar
authors.forename: E A
authors.initials: EA
authors.lastname: Agalamanyi
mesh_terms: D000328:Adult; D002638:Chewing Gum; D003743:Dental Enamel / Q000187:drug effects* / Q000473:pathology; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D004311:Double-Blind Method; D005247:Feeding Behavior; D005260:Female; D005459:Fluorides / Q000032:analysis / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008852:Microradiography; D008859:Microscopy, Polarization; D012463:Saliva / Q000737:chemistry / Q000378:metabolism; D012636:Secretory Rate; D013012:Sorbitol / Q000627:therapeutic use*; D017001:Tooth Demineralization / Q000473:pathology / Q000517:prevention & control*; D014089:Tooth Remineralization; D014100:Toothpastes; D014993:Xylitol / Q000627:therapeutic use*
chemical_list: D002638:Chewing Gum; D004040:Dietary Carbohydrates; D014100:Toothpastes; D013012:Sorbitol; D005459:Fluorides; D014993:Xylitol