title: Diarrhoeic shellfish toxins in Adriatic Sea mussels evaluated by an ELISA method.
abstract: A competitive enzyme immunoassay (ELISA) was used to determine the presence of okadaic acid (OA) and/or dinophysistoxin-1 (DTX-1) in mussels. The accuracy and sensitivity of the ELISA method has been checked. The sensitivity of the method (100 ng/g of hepatopancreas) makes it possible to determine OA concentrations ten times lower than the tolerance limits established by the Health Authorities of many countries. For the first time, OA and/or DTX-1 were detected in mussels (Mytilus galloprovincialis) collected in different stations along the Adriatic Sea coasts.
authors.affiliation: Institute of Pharmacology and Pharmacognosy, University of Trieste, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Tubaro
authors.forename: S
authors.initials: S
authors.lastname: Sosa
authors.forename: M
authors.initials: M
authors.lastname: Bruno
authors.forename: P M
authors.initials: PM
authors.lastname: Gucci
authors.forename: L
authors.initials: L
authors.lastname: Volterra
authors.forename: R
authors.initials: R
authors.lastname: Della Loggia
mesh_terms: D000818:Animals; D049872:Bivalvia / Q000737:chemistry*; D003967:Diarrhea / Q000139:chemically induced*; D004797:Enzyme-Linked Immunosorbent Assay; D004988:Ethers, Cyclic / Q000032:analysis*; D005517:Foodborne Diseases / Q000209:etiology*; D008387:Marine Toxins / Q000032:analysis*; D009792:Oceans and Seas; D019319:Okadaic Acid / Q000031:analogs & derivatives; D011714:Pyrans / Q000032:analysis
chemical_list: D004988:Ethers, Cyclic; D008387:Marine Toxins; D011714:Pyrans; D019319:Okadaic Acid; C051904:dinophysistoxin 1