[Activity of antioxidant system enzymes and lipid peroxidation product content in the liver and thymus of rats in the early stages of irradiation].
The activity of enzymes of the antioxidation system and the content of some lipid peroxidation products in the liver and thymus of irradiated (0.21 C/kg) rats have been investigated. Glutathione reductase and glutathione transferase activity in the liver and thymus of rats decreased during the first 24 h after irradiation. There was a phase change in the catalase activity during the initial postirradiation period. The content of malonic dialdehyde increased immediately after irradiation and somewhat decreased during the first 24 h. In 24 h, there observed a radiation-induced increase in the diene conjugate content in the liver and thymus of rats, against the background of low activity of such antioxidation system enzymes as glutathione transferase, glutathione reductase and catalase.
Verkhogliad
I N
IN
Tsudzevich
B A
BA
D000818:Animals; D002374:Catalase / Q000032:analysis*; D005260:Female; D005980:Glutathione Reductase / Q000032:analysis*; D005982:Glutathione Transferase / Q000032:analysis*; D015227:Lipid Peroxidation / Q000528:radiation effects*; D008099:Liver / Q000201:enzymology / Q000378:metabolism / Q000528:radiation effects*; D008297:Male; D008315:Malondialdehyde / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains; D013950:Thymus Gland / Q000201:enzymology / Q000378:metabolism / Q000528:radiation effects*; D013997:Time Factors
D008315:Malondialdehyde; D002374:Catalase; D005980:Glutathione Reductase; D005982:Glutathione Transferase
Aktivnost' fermentov antiokislitel'noĭ sistemy i soderzhanie produktov perekisnogo okisleniia lipidov v pecheni i timuse krys na rannikh étapakh luchevogo vozdeĭstviia.