title: Prophylactic laryngo-tracheal aerosolized lidocaine against postoperative sore throat.
abstract: A randomized, double-blind study was carried out on 193 ASA I-II surgical patients to assess the effect of aerosolized lidocaine on sore throat, hoarseness and cough in connection with tracheal intubation. The study group received aerosolized lidocaine 100 mg 2 min before tracheal intubation, using a spray. The control group received no spray. The patients underwent a standardized general anaesthesia. The patients were interviewed when leaving the recovery room and the next day in the ward. Specific questions were asked regarding sore throat, cough and hoarseness. There were no significant differences between the two groups, which suggests that topical anaesthesia of the mucosa of the upper airway is ineffective as a means of ameliorating airway complaints in connection with tracheal intubation.
authors.affiliation: Department of Anaesthesia, Aalborg Hospital, Denmark.
authors.forename: P
authors.initials: P
authors.lastname: Herlevsen
authors.forename: C
authors.initials: C
authors.lastname: Bredahl
authors.forename: K
authors.initials: K
authors.lastname: Hindsholm
authors.forename: P K
authors.initials: PK
authors.lastname: Kruhøffer
mesh_terms: D000280:Administration, Inhalation; D000328:Adult; D000336:Aerosols; D000368:Aged; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal / Q000009:adverse effects*; D008012:Lidocaine / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010612:Pharyngitis / Q000209:etiology / Q000517:prevention & control*; D011183:Postoperative Complications / Q000517:prevention & control*; D013514:Surgical Procedures, Operative
chemical_list: D000336:Aerosols; D008012:Lidocaine