[Effect of beta receptor blockaders on the status of the lysosomal system of peripheral blood neutrophils in rabbits with immobilization stress].
The investigation carried out on mature rabbits under conditions of beta-adrenoreceptors' blocking by obsidan has revealed that 12-hour immobilization caused neutrophilic leukocytosis in the peripheral blood, degranulation of neutrophils, increase of acid phosphatase activity. These changes occurred much earlier as compared with those in the control group were more pronounced and lasted for a less period of time. Consequently, beta-receptors are the necessary components in the formation of stress-syndrome under the influence of an +non-infectious stressor.
Lunina
V V
VV
Vovk
S B
SB
D000818:Animals; D002452:Cell Count / Q000187:drug effects; D015550:Cell Degranulation / Q000187:drug effects* / Q000502:physiology; D003864:Depression, Chemical; D004195:Disease Models, Animal; D005260:Female; D008247:Lysosomes / Q000187:drug effects* / Q000502:physiology; D008297:Male; D009504:Neutrophils / Q000187:drug effects* / Q000473:pathology / Q000648:ultrastructure; D011433:Propranolol / Q000494:pharmacology*; D011817:Rabbits; D012149:Restraint, Physical / Q000523:psychology; D013315:Stress, Psychological / Q000097:blood*; D013997:Time Factors
D011433:Propranolol
Vplyv blokady beta-retseptoriv na stan lizosomal'noho aparatu neĭtrofil'nykh leĭkotsitiv peryferychnoĭ krovi kroliv pri immobilizatsiĭnomu stresi.