[Adverse reactions to medications in patients in ambulatory otorhinolaryngology].
A 12 months prospective study to detect adverse drug reactions (ADR) was carried out in an ORL outpatients clinic. 52 patients (1.8%) out of 2891 examined suffered one or more ADRs. The incidence was higher in women and in older patients. 94% of the ADRs were mild to moderate and 3 patients suffered irreversible lesions. Reactions were most commonly located in the nervous system (50%) and gastrointestinal tract (21%). The most common drugs involved were cardiovascular (40%) and central nervous system (25%) active drugs. Papers concerning ADRs published from 1976 to 1985 in spanish otorhinolaringologic journals have also been analyzed. 0.88% of 1357 published papers described ADRs. The incidence of ADRs observed in our study is higher than expected from the low number of papers published on this subject.
Valladares
J
J
Servicio de Otorrinolaringología, Hospital General de Castellón, Universitat de Valencia.
Ferrer
J M
JM
Palop
V
V
Rubio
E
E
Morales Olivas
F J
FJ
D000293:Adolescent; D000328:Adult; D000368:Aged; D000553:Ambulatory Care; D002648:Child; D002675:Child, Preschool; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010036:Otolaryngology; D011446:Prospective Studies
Reacciones adversas a medicamentos en pacientes atendidos en consulta externa de otorrinolaringología.