title: Metabolism of the malignant cell, in vivo, is anaerobic and significantly plays a factor in the pathway to carcinogenesis.
abstract: The malignant cell, in vivo, metabolizes and respires anaerobically. For a good many years scientists have been aware of anaerobia being present in malignant growths. The prevailing opinion is that the malignant cell is able to remain viable in an anaerobic medium. This assumption is incorrect and is actually misleading. My investigative studies indicates that the malignant cell metabolizes and respires intracellularly so that the consequence of such a physiology is anaerobic and the basis for such anaerobia is a metabolic phenomenon. There is a reason for this anaerobiosis. Studies demonstrated the fact that there are present within the malignant cell and in the immediate area bacterial spores arising from one of several varieties of plant bacteria. And with an adequate circulating flow of blood, by the animal (human) host, to that particular site, provides the metabolites, enzymes, and the exchange of gases to enhance this abnormal physiopathological anaerobiosis. It is this intracellular anaerobic metabolism within an animal cell that becomes the basis for its malignant transformation.
authors.affiliation: North Detroit General Hospital, MI 48212.
authors.forename: M W
authors.initials: MW
authors.lastname: White
mesh_terms: D000693:Anaerobiosis; D000818:Animals; D001419:Bacteria / Q000302:isolation & purification* / Q000378:metabolism / Q000648:ultrastructure; D051379:Mice; D008811:Mice, Inbred DBA; D008854:Microscopy, Electron; D012513:Sarcoma, Experimental / Q000378:metabolism* / Q000382:microbiology / Q000473:pathology / Q000648:ultrastructure; D013171:Spores, Bacterial / Q000302:isolation & purification / Q000648:ultrastructure