title: Deletion mapping of H-Y antigen to the long arm of the human Y chromosome.
abstract: A gene encoding or controlling the expression of the H-Y transplantation antigen was previously mapped to the human Y chromosome. We now report the sublocalization of this gene on the long arm of the human Y chromosome. Eight patients with Y-chromosomal abnormalities were examined with a series of existing and new DNA markers for the Y chromosome. The resulting deletion map was correlated with H-Y antigen expression. We conclude that the H-Y antigen gene maps to a portion of deletion interval 6 that is identified by specific DNA markers.
authors.affiliation: Department of Pathology, University of Washington, Seattle 98195.
authors.forename: M A
authors.initials: MA
authors.lastname: Cantrell
authors.forename: J S
authors.initials: JS
authors.lastname: Bogan
authors.forename: E
authors.initials: E
authors.lastname: Simpson
authors.forename: J N
authors.initials: JN
authors.lastname: Bicknell
authors.forename: E
authors.initials: E
authors.lastname: Goulmy
authors.forename: P
authors.initials: P
authors.lastname: Chandler
authors.forename: R A
authors.initials: RA
authors.lastname: Pagon
authors.forename: D C
authors.initials: DC
authors.lastname: Walker
authors.forename: H C
authors.initials: HC
authors.lastname: Thuline
authors.forename: J M
authors.initials: JM
authors.lastname: Graham
mesh_terms: D000293:Adolescent; D001483:Base Sequence; D015139:Blotting, Southern; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D004247:DNA; D005819:Genetic Markers; D006182:H-Y Antigen / Q000235:genetics*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008969:Molecular Sequence Data; D014998:Y Chromosome
chemical_list: D005819:Genetic Markers; D006182:H-Y Antigen; D004247:DNA