title: Management of bile duct strictures. An evolving strategy.
abstract: In an effort to determine the role of interventional radiologic and endoscopic techniques in the management of benign biliary strictures, a retrospective analysis was carried out on 194 consecutive patients with bile duct strictures treated at UCLA between 1955 and 1990. Patients were classified as group 1 (1955 through 1979; n = 138) or group 2 (1980 through 1989; n = 56). Follow-up was for a minimum of 24 months and was in excess of 3 years in 179 patients (92%). Although the incidence of recurrent strictures was similar in the two groups (21% and 23%), the reoperation rate was significantly lower (P less than .02) in group 2 (6%) than in group 1 (21%). Percutaneous transhepatic biliary dilatation, used in 20 patients in group 2, was successful in 13 (93%) of 14 patients with anastomotic strictures and three (50%) of six patients with primary strictures (P less than .05). We conclude that surgical reconstruction remains the standard therapy for patients with primary bile duct strictures. Percutaneous transhepatic biliary dilatation has limited usefulness for these patients, but may be more appropriate for those with anastomotic strictures.
authors.affiliation: Department of Surgery, UCLA School of Medicine 90024.
authors.forename: J M
authors.initials: JM
authors.lastname: Millis
authors.forename: R K
authors.initials: RK
authors.lastname: Tompkins
authors.forename: M J
authors.initials: MJ
authors.lastname: Zinner
authors.forename: W P
authors.initials: WP
authors.lastname: Longmire
authors.forename: J J
authors.initials: JJ
authors.lastname: Roslyn
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000713:Anastomosis, Roux-en-Y; D001649:Bile Duct Diseases / Q000209:etiology / Q000601:surgery* / Q000628:therapy; D001653:Bile Ducts, Intrahepatic / Q000601:surgery; D002404:Catheterization / Q000379:methods; D002768:Choledochostomy; D003251:Constriction, Pathologic / Q000209:etiology / Q000601:surgery / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006500:Hepatic Duct, Common / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D015607:Stents; D016896:Treatment Outcome