The downstream regulatory sequence of the adenovirus type 2 major late promoter is functionally redundant.
Mutagenesis of promoter sequences and oligonucleotide competition assays have been used to demonstrate the late-phase-specific stimulation of the adenovirus type 2 major late promoter is mediated by functionally redundant elements located between positions +75 and +125. These octamer motif-related sequences are recognized by multiple factors.
Li
X C
XC
Department of Molecular Biology, Princeton University, New Jersey 08544-1014.
Huang
W L
WL
Flint
S J
SJ
D000260:Adenoviruses, Human / Q000235:genetics*; D001483:Base Sequence; D016384:Consensus Sequence; D004252:DNA Mutational Analysis; D004268:DNA-Binding Proteins / Q000378:metabolism; D006367:HeLa Cells; D006801:Humans; D008969:Molecular Sequence Data; D011401:Promoter Regions, Genetic / Q000235:genetics; D012045:Regulatory Sequences, Nucleic Acid / Q000235:genetics*
D004268:DNA-Binding Proteins