title: Immunohistochemical identification of Penicillium marneffei by monoclonal antibody.
abstract: We present an experimental study on the immunohistochemical identification of Penicillium marneffei in paraffin-embedded, formalin-fixed tissue. The monoclonal antibody EB-A1 detects a specific galactomannan that appears to have at least one epitope identical in P. marneffei and Aspergillus sp. This immunohistochemical approach could be useful in the diagnosis of a rare diseae, penicilliosis marneffei, which proves to be difficult to identify by conventional microscopy.
authors.affiliation: Department of Dermatopathology, CHU du Sart Tilman, Liège, Belgium.
authors.forename: J
authors.initials: J
authors.lastname: Arrese Estrada
authors.forename: D
authors.initials: D
authors.lastname: Stynen
authors.forename: J
authors.initials: J
authors.lastname: Van Cutsem
authors.forename: C
authors.initials: C
authors.lastname: Piérard-Franchimont
authors.forename: G E
authors.initials: GE
authors.lastname: Piérard
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal; D001230:Aspergillus / Q000276:immunology; D006168:Guinea Pigs; D016612:Paraffin Embedding / Q000379:methods*; D010407:Penicillium / Q000276:immunology / Q000302:isolation & purification*
chemical_list: D000911:Antibodies, Monoclonal