Oxygen radical generation and alkylating ability of mitomycin C bioactivated by xanthine dehydrogenase.
Gustafson
D L
DL
Department of Nutrition and Cellular and Molecular Pharmacology and Physiology Program, University of Nevada, Reno 89557-0132.
Pritsos
C A
CA
D000477:Alkylating Agents / Q000494:pharmacology*; D000818:Animals; D001711:Biotransformation; D002851:Chromatography, High Pressure Liquid; D005609:Free Radicals; D051379:Mice; D008819:Mice, Nude; D016685:Mitomycin / Q000378:metabolism / Q000494:pharmacology*; D009368:Neoplasm Transplantation; D010101:Oxygen Consumption / Q000187:drug effects*; D014184:Transplantation, Homologous; D014968:Xanthine Dehydrogenase / Q000378:metabolism*
D000477:Alkylating Agents; D005609:Free Radicals; D016685:Mitomycin; D014968:Xanthine Dehydrogenase