The IC50: an exactly defined measure of antibiotic sensitivity.
The concentration of gentamicin that inhibits the growth of half of an inoculum of Pseudomonas aeruginosa (IC50) was estimated by doing viable bacterial counts with varying concentrations of gentamicin and fitting a probit inhibition curve to the results. This is a more precisely defined measure than the MIC and its standard error is readily calculable.
Soothill
J S
JS
Burns Research Group, Birmingham Accident Hospital, UK.
Ward
R
R
Girling
A J
AJ
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D008826:Microbial Sensitivity Tests / Q000379:methods*; D012680:Sensitivity and Specificity
D000900:Anti-Bacterial Agents