Prevention of malodor from intraoral gauze tamponade with the topical use of clindamycin.
Azulene ointment with a small dose of clindamycin was used topically in eight patients with maxillary cancer with the intent to inhibit the malodor that originates from a gauze tamponade applied to the postoperative maxillary bony defect. The malodor was either markedly decreased or eliminated in all cases. Concurrent with the decrease or elimination of the malodor, anaerobic microorganisms such as Bacteroides and Peptostreptococcus, which are considered to be involved in the generation of malodor, also became undetectable.
Ogura
T
T
First Department of Oral and Maxillofacial Surgery, Osaka University Faculty of Dentistry, Japan.
Urade
M
M
Matsuya
T
T
D000287:Administration, Topical; D000293:Adolescent; D000368:Aged; D001419:Bacteria / Q000187:drug effects; D002981:Clindamycin / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D008441:Maxillary Neoplasms / Q000601:surgery*; D008875:Middle Aged; D009779:Occlusive Dressings; D009812:Odorants / Q000517:prevention & control*; D013530:Surgical Wound Infection / Q000188:drug therapy* / Q000382:microbiology
D002981:Clindamycin