title: Congenital tremor in Holstein Friesian-cattle.
abstract: In a female family line of Holstein-Friesian cattle a series of trembling calves was born within a period of ten years. All trembling animals were male; female calves appeared normal. At necropsy of one calf severe degenerative lesions of spinal cord and brain white matter were observed. Both myelin and axons were lost and some macrophages occurred within digestion chambers. Obviously degenerated neurones were not found. The lesion was interpreted as a single recessive sex-linked hereditary trait.
authors.affiliation: Veterinary Practice Z. O. Drenthe, Coevorden, The Netherlands.
authors.forename: M
authors.initials: M
authors.lastname: Bethlehem
authors.forename: E
authors.initials: E
authors.lastname: Gruys
authors.forename: L
authors.initials: L
authors.lastname: Elving
mesh_terms: D000818:Animals; D001921:Brain / Q000473:pathology*; D001947:Breeding; D002417:Cattle; D002418:Cattle Diseases / Q000151:congenital* / Q000235:genetics / Q000473:pathology; D005260:Female; D008297:Male; D010375:Pedigree; D012737:Sex Factors; D013116:Spinal Cord / Q000473:pathology*; D014202:Tremor / Q000151:congenital / Q000235:genetics / Q000473:pathology / Q000662:veterinary*