Anti-hCG vaccines are in clinical trials.
Two vaccines inducing antibodies against human chorionic gonadotropin (hCG) have completed Phase I clinical trials, indicating the reversibility and safety of these vaccines. One is currently in Phase II efficacy trials in women in three major centres in India. The available data suggest that the vaccine prevents pregnancy above antibody titres of 50 ng/ml hCG bioneutralization capacity.
Talwar
G P
GP
National Institute of Immunology, New Delhi, India.
Singh
O
O
Pal
R
R
Chatterjee
N
N
D000906:Antibodies / Q000032:analysis; D006063:Chorionic Gonadotropin / Q000276:immunology*; D003267:Contraception / Q000379:methods*; D005260:Female; D006801:Humans; D007114:Immunization; D008175:Lung Neoplasms / Q000628:therapy; D014612:Vaccines
D000906:Antibodies; D006063:Chorionic Gonadotropin; D014612:Vaccines