title: Basic biochemistry of cell surface carbohydrates and aspects of the tissue distribution of histo-blood group ABH and related glycosphingolipids.
abstract: Cell surface carbohydrates may be protein- or lipid-linked. The structural polymorphism of the oligosaccharide chains is extensive due to variations in monosaccharide composition, carbohydrate sequence, branching, linkage position and linkage anomericity. Blood group ABH and related glycosphingolipids show a remarkable tissue-specific expression with possible implications in areas such as transfusion medicine, transplantation surgery and oncology. This communication gives a condensed description of the present knowledge of the tissue-specific distribution of histo-blood glycolipids in humans.
authors.affiliation: Department of Medical Biochemistry, University of Gothenburg, Sweden.
authors.forename: J
authors.initials: J
authors.lastname: Holgersson
authors.forename: M E
authors.initials: ME
authors.lastname: Breimer
authors.forename: B E
authors.initials: BE
authors.lastname: Samuelsson
mesh_terms: D000017:ABO Blood-Group System / Q000737:chemistry* / Q000378:metabolism; D000954:Antigens, Surface / Q000737:chemistry; D002240:Carbohydrate Sequence; D006028:Glycosphingolipids / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D007983:Lewis Blood Group Antigens / Q000737:chemistry / Q000378:metabolism; D008562:Membrane Glycoproteins / Q000737:chemistry / Q000378:metabolism; D008969:Molecular Sequence Data; D014018:Tissue Distribution
chemical_list: D000017:ABO Blood-Group System; D000954:Antigens, Surface; D006028:Glycosphingolipids; D007983:Lewis Blood Group Antigens; D008562:Membrane Glycoproteins