[Environmental pollutants and fertility disorders. Heavy metals and minerals].
So far, the influence of lead, cadmium and mercury on human fertility has hardly been considered. First experiences by the authors with the chelating agent 2,3 dimercaptopropane-1-sulfonate (DMPS), which mobilizes heavy metals deposited in the body, seem to favour an association between the body load of heavy metals and complications during the menstrual cycle and during pregnancy. By means of an extensive survey of references, the importance of heavy metals for reproduction is demonstrated. In addition, the deficiency of particular minerals and their interaction with heavy metals are considered. Indications are given for diagnosis and therapy of the exposure to heavy metals. The practical procedure is demonstrated by means of three case studies.
Gerhard
I
I
Abteilung für Gynäkologische Endokrinologie und Fertilitätsstörungen, Universitäts-Frauenklinik, Heidelberg.
Runnebaum
B
B
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000328:Adult; D000818:Animals; D002105:Cadmium Poisoning / Q000150:complications / Q000175:diagnosis; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007247:Infertility, Female / Q000139:chemically induced*; D007855:Lead Poisoning / Q000150:complications / Q000175:diagnosis; D008630:Mercury Poisoning / Q000150:complications / Q000175:diagnosis; D008670:Metals / Q000009:adverse effects*; D008903:Minerals / Q000009:adverse effects*; D016273:Occupational Exposure; D011247:Pregnancy; D012307:Risk Factors
D008670:Metals; D008903:Minerals
Schadstoffe und Fertilitätsstörungen. Schwermetalle und Mineralstoffe.