title: Interchromosomal gene conversion as a possible mechanism for explaining divergence patterns of ZFY-related genes.
abstract: The divergence pattern of mammalian ZFY-related genes from human (ZFY and ZFX) and mouse (Zfy-1 and Zfx) was reexamined on the basis of nucleotide substitutions at the synonymous codon-alternating positions. It is possible to explain the unusual divergence pattern of the mammalian Y-linked ZF genes by interchromosomal gene conversion by X-linked ZF genes. Furthermore, the rates of evolution of mammalian X- and Y-linked ZF genes were shown to agree well with those expected from our model.
authors.forename: H
authors.initials: H
authors.lastname: Hayashida
authors.forename: K
authors.initials: K
authors.lastname: Kuma
authors.forename: T
authors.initials: T
authors.lastname: Miyata
mesh_terms: D000818:Animals; D004268:DNA-Binding Proteins / Q000235:genetics*; D005785:Gene Conversion; D014644:Genetic Variation; D006801:Humans; D051741:Kruppel-Like Transcription Factors; D051379:Mice; D014157:Transcription Factors; D016335:Zinc Fingers / Q000235:genetics*
chemical_list: D004268:DNA-Binding Proteins; D051741:Kruppel-Like Transcription Factors; D014157:Transcription Factors; C054430:ZFY protein, human; C501342:Zfy1 protein, mouse; C062076:zinc finger protein, X-linked