title: Calcium and calmodulin.
abstract: A description of the value of calcium and calmodulin is given in terms of their dynamics and structures. It is insisted that a full appreciation of their value demands recognition of the time domain, motion, in evolution in concert with structure. Only in this way can homeostasis of resting states as well as triggering, assisted by calcium/calmodulin, be described. The best analogy is with a regulatory electrical control such as household central heating system where calcium carries the current and calmodulin triggers the heating (cellular work) and the pumps (cellular pumps). There is full feed-back control.
authors.affiliation: Inorganic Chemistry Laboratory, Oxford, UK.
authors.forename: R J
authors.initials: RJ
authors.lastname: Williams
mesh_terms: D002118:Calcium / Q000737:chemistry* / Q000502:physiology; D002147:Calmodulin / Q000737:chemistry* / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology
chemical_list: D002147:Calmodulin; D002118:Calcium