title: Juvenile chronic myelocytic leukemia with unusual cytogenetic clonal evolution.
abstract: Cytogenetic studies are reported in a case of juvenile chronic myelocytic leukemia with dysmyelopoiesis and skin involvement. The clonal evolution of a 6q-anomaly is described. Hematological and cytogenetic findings suggest a role of hematopoietic stem cell in this patient for whom the outcome was fatal.
authors.affiliation: Laboratoire d'Hématologie, Hôpital Avicenne, Bobigny, France.
authors.forename: V
authors.initials: V
authors.lastname: Eclache
authors.forename: J
authors.initials: J
authors.lastname: Van den Akker
authors.forename: C
authors.initials: C
authors.lastname: Perot
authors.forename: J L
authors.initials: JL
authors.lastname: Taillemite
authors.forename: M
authors.initials: M
authors.lastname: Nathanson
authors.forename: G
authors.initials: G
authors.lastname: Leverger
authors.forename: P
authors.initials: P
authors.lastname: Lortholary
mesh_terms: D002675:Child, Preschool; D002999:Clone Cells / Q000502:physiology; D005260:Female; D006801:Humans; D007621:Karyotyping; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000235:genetics*