title: Maximum likelihood estimation of signal detection model parameters for the assessment of two-stage diagnostic strategies.
abstract: The methodology of Receiver Operating Characteristic curves based on the signal detection model is extended to evaluate the accuracy of two-stage diagnostic strategies. A computer program is developed for the maximum likelihood estimation of parameters that characterize the sensitivity and specificity of two-stage classifiers according to this extended methodology. Its use is briefly illustrated with data collected in a two-stage screening for auditory defects.
authors.affiliation: Cuban Neuroscience Center, Havana.
authors.forename: R B
authors.initials: RB
authors.lastname: Lirio
authors.forename: I C
authors.initials: IC
authors.lastname: Dondériz
authors.forename: M C
authors.initials: MC
authors.lastname: Pérez Abalo
mesh_terms: D000465:Algorithms; D003936:Diagnosis, Computer-Assisted; D006801:Humans; D016013:Likelihood Functions; D011336:Probability; D012984:Software