TA-3037A, a new inhibitor of glutathione S-transferase, produced by actinomycetes. II. Structure determination.
TA-3037A, a new inhibitor of glutathione S-transferase, has been isolated from the culture broth of Streptomyces sp. TA-3037. The structure of TA-3037A was defined as (Z)-3-benzylidene-3,4-dihydro-2-oxo-2H-1,4-benzoxazine-5-carboxylic acid by an analysis of spectral properties and chemical studies of TA-3037A and its derivatives.
Komagata
D
D
Institute of Microbial Chemistry, Tokyo, Japan.
Muraoka
Y
Y
Sawa
R
R
Takahashi
Y
Y
Naganawa
H
H
Sawa
T
T
Takeuchi
T
T
D005982:Glutathione Transferase / Q000037:antagonists & inhibitors*; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D010078:Oxazines / Q000032:analysis / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D010078:Oxazines; C076479:TA 3037A; D005982:Glutathione Transferase