title: Localization of vasoactive intestinal peptide (VIP) messenger RNA (mRNA) in amacrine cells of rat retina.
abstract: We detected vasoactive intestinal peptide (VIP) messenger RNA (mRNA) in the rat retina using an in situ hybridization technique and a 35S-labelled cDNA probe. VIP mRNA was present in the cells of the inner nuclear layer (INL). The VIP mRNA-positive cells showed a distribution similar to that of the VIP-like immunoreactive amacrine cells. This observation suggests that VIP mRNA undergoes transcription in the VIP-immunoreactive amacrine cells.
authors.affiliation: Department of Ophthalmology, Kyoto Prefectural University of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Okamoto
authors.forename: H
authors.initials: H
authors.lastname: Okamura
authors.forename: H
authors.initials: H
authors.lastname: Terubayashi
authors.forename: Y
authors.initials: Y
authors.lastname: Akagi
authors.forename: H
authors.initials: H
authors.lastname: Okamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Ibata
mesh_terms: D000818:Animals; D001345:Autoradiography; D015342:DNA Probes; D007150:Immunohistochemistry; D008297:Male; D009693:Nucleic Acid Hybridization; D012333:RNA, Messenger / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains; D012160:Retina / Q000737:chemistry* / Q000166:cytology; D014660:Vasoactive Intestinal Peptide / Q000032:analysis*
chemical_list: D015342:DNA Probes; D012333:RNA, Messenger; D014660:Vasoactive Intestinal Peptide