Survival of children with chronic myeloid leukemia.
We analyzed survival in 203 children with Philadelphia-chromosome-positive chronic myeloid leukemia (CML). Median survival was 4.1 years; average annual risk of death was 20%. These survival data are similar to those reported in adults. Because there is no possibility of long-term disease-free survival in children with CML with conventional therapies, the findings of this study suggest that bone marrow transplantation should be considered in these patients.
Marin
T
T
Department of Pediatric Hematology, Centro Medico La Raza IMSS, Mexico City, Mexico.
Butturini
A
A
Kantarjian
H
H
Sokal
J
J
Mickey
M R
MR
Gale
R
R
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000401:mortality*; D008297:Male; D011379:Prognosis; D015996:Survival Rate