[Presence of calretinin in neurons of the human intestine].
Calcium-binding proteins are present in different neuron populations in the Central Nervous System. As concerns the Enteric Nervous System, only a few studies have been performed. In the present work we investigated immunohistochemically the localization of Calretinin in neurons of the human intestinal wall. Our results showed the presence of stained cell bodies and fibers with antibodies against Calretinin in the Auerbach plexus. Since most of the enteric neurons are characterized by a slow phase after hyperpolarization caused by Ca2+ dependent K+ channels, the role of Calretinin could be to modulate this particular electrophysiological behaviour.
Celio
M R
MR
Institut Histologie et Embryologie-Université de Fribourg CH.
Poncino
A
A
Cantino
D
D
D064032:Calbindin 2; D002118:Calcium / Q000378:metabolism; D003106:Colon / Q000294:innervation*; D003593:Cytoplasm / Q000737:chemistry; D006801:Humans; D009197:Myenteric Plexus / Q000737:chemistry* / Q000166:cytology; D009419:Nerve Tissue Proteins / Q000032:analysis*; D009474:Neurons / Q000737:chemistry; D064030:S100 Calcium Binding Protein G / Q000032:analysis*; D013368:Submucous Plexus / Q000737:chemistry* / Q000166:cytology
C576764:CALB2 protein, human; D064032:Calbindin 2; D009419:Nerve Tissue Proteins; D064030:S100 Calcium Binding Protein G; D002118:Calcium
Presenza di calretinina nei neuroni dell'intestino umano.