title: [Osteoma cutis. Pathogenesis and therapeutic possibilities].
abstract: No efficacious therapy for the treatment of increasing and spreading cutaneous ossification is yet established. We report a 52 year old white female with multiple miliary osteomas of the skin involving face, chest and back. The patient has a history of acne vulgaris. A therapeutic trial with a diphosphonate (etidronate disodium) was started in order to stop marked progression and appearance of new lesions. In accordance with the two previously described cases of the literature we failed to achieve any improvement. Clinical features, etiology, classification and therapy of osteoma cutis are discussed.
authors.affiliation: Dermatologische Klinik und Poliklinik, Technischen Universität, München.
authors.forename: G
authors.initials: G
authors.lastname: Schuhmachers
authors.forename: W I
authors.initials: WI
authors.lastname: Worret
mesh_terms: D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology; D003937:Diagnosis, Differential; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D012968:Etidronic Acid / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy / Q000473:pathology*; D010016:Osteoma / Q000188:drug therapy / Q000473:pathology*; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology*
chemical_list: D012968:Etidronic Acid
vernacular_title: Osteoma cutis. Pathogenese und therapeutische Möglichkeiten.