[Interposition connectors with heparin coating for vascular anastomosis of microsurgical tissue flaps].
The intraluminal surface of interposition connectos which are introduced for the quick vascular connection of microsurgical free flaps was coated by heparin. This heparin coating proved to be stable at the polyurethane wall until the intraluminal surface of the interposition connectors with a length of 15 mm was coated by a layer of endothelial cells. 90% of the experimental venous connections didn't show a thrombus formation and were open for the blood flow 10 days postoperatively. The experimental free flaps which were connected by this way had survived 21 days postoperatively and showed a regular healing.
Mayer
B
B
Hals-Nasen-Ohren-Klinik, Universitätsklinikum Rudolf Virchow der FU Berlin.
Kretschmer
R
R
Gunzenhäusser
E
E
D000714:Anastomosis, Surgical / Q000295:instrumentation*; D000818:Animals; D004730:Endothelium, Vascular / Q000473:pathology; D006493:Heparin; D008866:Microsurgery / Q000295:instrumentation*; D009131:Muscle, Smooth, Vascular / Q000601:surgery*; D015607:Stents; D013524:Surgical Flaps / Q000295:instrumentation*; D013536:Suture Techniques / Q000295:instrumentation; D013552:Swine; D014654:Vascular Patency / Q000502:physiology
D006493:Heparin
Interpositionskonnektoren mit Heparinbeschichtung für den Gefässanschluss mikrochirurgischer Gewebelappen.