[Prophylaxis in prostatic surgery with aztreonam. Our experience].
Aztreonam is a monobactam antibiotic with a very specific spectrum of action for gram-negative aerobic bacteria. Since these bacteria are responsible for most of the urinary tract infections, we conducted a study to determine its efficacy in the prophylaxis and treatment of infections in prostate surgery, one of the most common procedures performed in our field. Thirty-two patients received 1 gm Aztreonam at the time of anesthetic induction and q 8 h thereafter to a total dose of 3 gm. Cultures were performed before and 72 h after surgery. Twenty-eight patients had no complications and a sterile urine culture or less than 10,000 colonies, 2 developed wound infection from Staph, aureus and 1 had more than 100,000 colonies of Enterococci in urine. The foregoing findings indicate that Aztreonam is useful for prophylaxis and treatment of urinary tract infections in prostate surgery.
Moyano Calvo
J L
JL
Servicio de Urología, Hospital La Princesa, Universidad Autónoma, Madrid, España.
Arellano Gañán
R
R
Sempere Gutiérrez
A
A
Sanz Sacristán
J
J
Teba del Pino
F
F
Melón Rey
F J
FJ
Herrero Torres
L
L
Pereira Sanz
I
I
D000368:Aged; D000369:Aged, 80 and over; D001398:Aztreonam / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*; D011292:Premedication; D011469:Prostatic Diseases / Q000601:surgery*; D014552:Urinary Tract Infections / Q000517:prevention & control*
D001398:Aztreonam
Profilaxis en cirugía prostática con Aztreonam. Nuestra experiencia.