title: [Ultrastructural characteristics of the venous endothelium in primary varices of the legs].
abstract: The author establishes by using TEM a considerable variability of endothelial cell ultrastructure in primary varicose veins. Endothelial cells of varicose veins differ from these in normal ones by deformation of configuration of the cells and of their nucleus accompanied by alterations in other cellular organelles. These changes express the stimulation of the endothelial cell aiming their adaptation to hemodynamic changes ABD combine with destructive intracellular changes as well. Probably, adaptation capacities of endothelial cells are restricted to definite limits in which they can change themselves. Beyond these limits endothelial cells can not compensate and undergo degenerative alterations. The author discusses the possible functional changes of the venous endothelium related to substance transport in the venous wall, to lipid accumulation in the endothelium and to thrombus formation.
authors.affiliation: Département d'anatomie et d'histologie, Université Médicale de Varna, Bulgarie.
authors.forename: G R
authors.initials: GR
authors.lastname: Marinov
mesh_terms: D008841:Actin Cytoskeleton / Q000648:ultrastructure; D000328:Adult; D001485:Basement Membrane / Q000648:ultrastructure; D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D004730:Endothelium, Vascular / Q000648:ultrastructure*; D006801:Humans; D008055:Lipids; D008854:Microscopy, Electron; D008875:Middle Aged; D012501:Saphenous Vein / Q000648:ultrastructure*; D014617:Vacuoles / Q000648:ultrastructure; D014648:Varicose Veins / Q000473:pathology*
chemical_list: D008055:Lipids
vernacular_title: Particularités ultrastructurales de l'endothélium veineux dans la varicose primitive des membres inférieurs.