title: The role of cancer risk in the regulation of industrial pollution.
abstract: The extent of carcinogen regulation under existing U.S. environmental statutes is assessed by developing measures of the scope and stringency of regulation. While concern about cancer risk has played an important political role in obtaining support for pollution control programs, it has not provided the predominant rationale for most regulatory actions taken to date. Less than 20% of all standards established to limit concentrations of chemicals in various media address carcinogens. Restrictions on chemical use are more frequently based on concerns about noncancer human health or ecological effects. Of the chemicals in commercial use which have been identified as potential human carcinogens on the basis of rodent bioassays, only a small proportion are regulated. There is an inverse relationship between the scope of regulatory coverage and the stringency of regulatory requirements: the largest percentages of identified carcinogens are affected by the least stringent requirements, such as information disclosure. Standards based on de minimis cancer risk levels have been established for only 10% of identified carcinogens and are restricted to one medium: water. Complete bans on use have affected very few chemicals. The general role that carcinogenicity now plays in the regulatory process is not dramatically different from that of other adverse human health effects: if a substance is identified as a hazard, it may eventually be subject to economically achievable and technically feasible restrictions.
authors.affiliation: School of Public Health, University of California, Berkeley 94720.
authors.forename: W S
authors.initials: WS
authors.lastname: Pease
mesh_terms: D002274:Carcinogens, Environmental / Q000009:adverse effects*; D004787:Environmental Pollution / Q000331:legislation & jurisprudence*; D006801:Humans; D009369:Neoplasms / Q000209:etiology*; D009784:Occupational Diseases / Q000209:etiology*; D016272:Occupational Health / Q000331:legislation & jurisprudence; D012307:Risk Factors; D014481:United States
chemical_list: D002274:Carcinogens, Environmental