title: A rare complication due to sulfuric acid ingestion.
abstract: The authors present a case of pyloric and duodenal obstruction in an 8-year-old child, resulting from accidental ingestion of sulfuric acid. A marked pyloric and duodenal cicatrizing stenosis resulting from ingestion of sulfuric acid is seen infrequently, especially in pediatric age. Sulfuric acid produces a coagulation necrosis of the gastric mucosa and submucosa, and the process may involve the entire thickness of the gastric wall, with subsequent ulceration and fibrosis. This dynamic pathophysiologic event imposes postponement of surgical intervention because of various time length between ingestion of acid and onset of gastric outlet obstruction (17 days to 5 years). Clinical features included postprandial epigastric distress, repeated non-bilious vomiting, and marked weight loss. The authors also discuss the various surgical procedures that were employed to relieve the obstruction. Notwithstanding a potential risk of malignant evolution, a gastro-jejunostomy is the treatment of choice because of the age of the patient, and good postoperative results are confirmed by barium studies.
authors.affiliation: Surgical Emergency and Pediatric Surgery Department, Giannina Gaslini Institute, Genoa, Italy.
authors.forename: A M
authors.initials: AM
authors.lastname: Tamisani
authors.forename: C
authors.initials: C
authors.lastname: Di Noto
authors.forename: E
authors.initials: E
authors.lastname: Di Rovasenda
mesh_terms: D002057:Burns, Chemical / Q000175:diagnosis / Q000601:surgery*; D002648:Child; D002921:Cicatrix / Q000175:diagnosis / Q000601:surgery; D004380:Duodenal Obstruction / Q000139:chemically induced* / Q000175:diagnosis / Q000601:surgery; D004386:Duodenum / Q000293:injuries*; D005753:Gastric Mucosa / Q000187:drug effects* / Q000601:surgery; D005763:Gastroenterostomy; D006801:Humans; D008297:Male; D011707:Pyloric Stenosis / Q000139:chemically induced* / Q000175:diagnosis / Q000601:surgery; D013270:Stomach / Q000293:injuries*; D013464:Sulfuric Acids / Q000506:poisoning*; D014463:Ultrasonography
chemical_list: D013464:Sulfuric Acids; C033158:sulfuric acid