[Measurement of serum protein-bound hexose--an aid in the diagnosis and after-care of colorectal cancers?].
In a group of 80 patients with colorectal carcinoma and a control group of 103 persons Protein-bound Hexose (PHex) was measured in the serum. The level was, as reported previously by other authors, significantly elevated in the tumour group. The aim of this study was to compare the sensitivity of PHex with that of the oncofetal antigens CEA and CA 19/9. The sensitivity of PHex turned out to be clearly lower than that of CEA. It was about as high as the sensitivity of CA 19/9 in colorectal carcinoma. In view of these results there is no benefit to be expected from an introduction of the PHex determination into clinical practice.
Putzki
H
H
Klinik und Poliklinik für Allgemeinchirurgie, Medizinischen Hochschule Hannover.
Reichert
B
B
Hue
M
M
D000210:Acute-Phase Reaction / Q000097:blood / Q000175:diagnosis; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000097:blood; D014408:Biomarkers, Tumor / Q000097:blood*; D002272:Carcinoembryonic Antigen / Q000097:blood; D015179:Colorectal Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006601:Hexoses / Q000097:blood*; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000097:blood / Q000175:diagnosis* / Q000601:surgery; D011485:Protein Binding / Q000502:physiology; D012372:ROC Curve
D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D006601:Hexoses
Die Messung der Proteingebundenen Hexose im Serum--ein Hilfsmittel bei Diagnose und Nachsorge von kolorektalen Karzinomen?