title: Escherichia coli associated with acute measles and diarrhoea at Kenyatta National Hospital, Kenya.
abstract: Three hundred and three children under 5 years old with acute measles and diarrhoea (cases) and 300 other age-matched children with diarrhoea (controls) were examined for enteroadherent E. coli (EAEC) and other agents including rotavirus and Cryptosporidium. EAEC was determined by tissue culture of HEP-2 cells. Other agents were determined by conventional methods. EAEC was identified from both cases and control accounting for 10.3% (31/303) and 15.2% (46/300) respectively. Other bacterial agents were: 10.3% (31/303) from cases and 12.8% (39/300) from controls. A higher detection rate of enteroparasites was found among cases 15% (45/300) than controls 8.9% (27/300) whereas rotavirus was the reverse, 3% (9/303) in cases and 30.3% (92/300) in controls. To our knowledge characterization of EAEC has not been done before and therefore might be attributing factor to some of our unexplained diarrhoeal cases.
authors.affiliation: Centre for Microbiology Research, Kenya Medical Research Institute.
authors.forename: F C
authors.initials: FC
authors.lastname: Sang
authors.forename: S K
authors.initials: SK
authors.lastname: Kangethe
authors.forename: V A
authors.initials: VA
authors.lastname: Orinda
authors.forename: Z
authors.initials: Z
authors.lastname: Gatheru
authors.forename: R E
authors.initials: RE
authors.lastname: Black
authors.forename: P G
authors.initials: PG
authors.lastname: Waiyaki
mesh_terms: D002675:Child, Preschool; D003967:Diarrhea / Q000209:etiology*; D004926:Escherichia coli / Q000145:classification*; D004927:Escherichia coli Infections / Q000150:complications* / Q000453:epidemiology / Q000382:microbiology; D006779:Hospitals, Public; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007630:Kenya / Q000453:epidemiology; D008457:Measles / Q000150:complications*; D008826:Microbial Sensitivity Tests; D015995:Prevalence; D012703:Serotyping