title: [Presence and significance of anticardiolipin antibodies in infectious diseases].
abstract: IgG and IgM anti-cardiolipin antibodies were measured, by an ELISA technique, in the sera of patients with B hepatitis (28), infectious mononucleosis (10), chicken pox (12), HIV infection (20), acquired toxoplasmosis (41) and other infectious diseases [HBsAg+ chronic hepatitis (5), brucellosis (6), herpes zoster (4), boutonneuse fever (3), viral pneumonitis (4), rheumatic fever (2)]. Increased levels of anti-cardiolipin antibodies (aCL), at least in one immunoglobulin class, were detected in 37 out of 135 patients [27.4%; range: 7.3% (in the patients with toxoplasmosis) -80% (in the patients with HIV infection)]. Low or medium titer aCL were present in 28 patients, high titer in 9 (6 with HIV infection, 2 with chicken pox and I with lymphoadenopathic toxoplasmosis). None of the manifestations associated with aCL was present in the aCL-positive patients. Finally, positivity for aCL didn't seem to modify the clinical picture and the prognosis of the infectious disease.
authors.affiliation: Istituto di Patologia medica e Medicina mediterranea, Università, Messina.
authors.forename: A
authors.initials: A
authors.lastname: Barrile
authors.forename: P
authors.initials: P
authors.lastname: Quattrocchi
authors.forename: D
authors.initials: D
authors.lastname: Bonanno
authors.forename: A
authors.initials: A
authors.lastname: Crisafi
authors.forename: A
authors.initials: A
authors.lastname: Staiti
authors.forename: G
authors.initials: G
authors.lastname: Magaraci
authors.forename: S
authors.initials: S
authors.lastname: Romano
authors.forename: G
authors.initials: G
authors.lastname: Sturniolo
authors.forename: R
authors.initials: R
authors.lastname: Ricciardi
authors.forename: B
authors.initials: B
authors.lastname: Ferlazzo
mesh_terms: D000293:Adolescent; D000328:Adult; D000906:Antibodies / Q000032:analysis*; D002308:Cardiolipins / Q000276:immunology*; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007239:Infections / Q000276:immunology*; D008297:Male; D008875:Middle Aged
chemical_list: D000906:Antibodies; D002308:Cardiolipins; D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: Sulla presenza e sul significato degli anticorpi anti-cardiolipina nelle malattie infettive.