title: [Use of highly purified subvirion trivalent flue vaccine ("Grippovak") in groups with a high risk of complications].
abstract: During the epidemic season of 1989-1990 the subunit vaccine Grippovac was used in 20 asylums for old people and psychoneurological invalids in Moscow for the protection of the inhabitants and the personnel from influenza. Follow-up of the vaccinees during the period from November 1989 to March 1990 revealed that the use of this vaccine decreased the incidence of influenza-like diseases (ILD) 3.4-4.1 times among the vaccinees in comparison with that in the nonvaccinated control groups and significantly decreased the severity of the course of ILD, as well as the mortality because of ILD, among those vaccinees who had contacted ILD. This is indicative of good prospects of regular vaccinal prophylaxis of influenza at asylums for old people and other persons at a high risk of influenza complications.
authors.forename: M P
authors.initials: MP
authors.lastname: Chumakov
authors.forename: N A
authors.initials: NA
authors.lastname: Beregovskiĭ
authors.forename: M B
authors.initials: MB
authors.lastname: Linev
authors.forename: F N
authors.initials: FN
authors.lastname: Reĭzin
authors.forename: L P
authors.initials: LP
authors.lastname: Malyshkina
authors.forename: M N
authors.initials: MN
authors.lastname: Matrosovich
authors.forename: L I
authors.initials: LI
authors.lastname: Mart'ianova
authors.forename: A F
authors.initials: AF
authors.lastname: Piatnitskaia
authors.forename: M V
authors.initials: MV
authors.lastname: Solov'eva
mesh_terms: D005500:Follow-Up Studies; D006801:Humans; D009980:Influenza A virus / Q000472:pathogenicity; D009981:Influenza B virus / Q000472:pathogenicity; D007252:Influenza Vaccines / Q000627:therapeutic use*; D007251:Influenza, Human / Q000382:microbiology / Q000401:mortality / Q000503:physiopathology / Q000517:prevention & control*; D012307:Risk Factors
chemical_list: D007252:Influenza Vaccines
vernacular_title: Primenenie glubokoochishchennoĭ subvirionnoĭ trekhvalentnoĭ grippoznoĭ vaktsiny ("Grippovak") v gruppakh vysokogo riska oslozhneniĭ.