title: Diagnosis, prevalence and drug resistance of mycobacteria in HIV-positive and HIV-negative patients of an urban population in Germany.
abstract: In a survey of 3004 clinical specimens from 1112 HIV-negative and 679 clinical specimens from 140 HIV-positive patients which were submitted to our mycobacterial laboratory, we have analysed the different diagnostic approaches concerning mycobacterial disease in these two populations. We have assessed specimen-type, culture result, microscopical diagnosis and prevalence in relation to HIV status. Isolation rates of mycobacteria were highest in blood cultures from HIV-positive patients. 10 out of 140 HIV-positive patients had positive mycobacterial culture results. All 10 had positive blood cultures, but only three of them were positive for M. tuberculosis.
authors.affiliation: Institut für Medizinische Mikrobiologie und Infektionsimmunologie, Freie Universität Berlin, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Ratei
authors.forename: W
authors.initials: W
authors.lastname: Zaki
authors.forename: J
authors.initials: J
authors.lastname: Wagner
authors.forename: H
authors.initials: H
authors.lastname: Hahn
mesh_terms: D000995:Antitubercular Agents / Q000494:pharmacology; D001604:Berlin / Q000453:epidemiology; D004352:Drug Resistance, Microbial; D006679:HIV Seropositivity / Q000150:complications / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D009161:Mycobacterium / Q000187:drug effects* / Q000302:isolation & purification; D009164:Mycobacterium Infections / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D015995:Prevalence; D013045:Species Specificity; D014505:Urban Population
chemical_list: D000995:Antitubercular Agents