title: Extracorporeal shock wave lithotripsy and xanthine calculi in Lesch-Nyhan syndrome.
abstract: We report a case of Lesch-Nyhan syndrome (LNS) with urinary xanthine calculi. At eight years of age calculi in the renal pelvis were successfully disintegrated by extracorporeal shock wave lithotripsy (ESWL) without any complications. Follow-up sonography is very useful for management of patients with LNS, particularly when they are on allopurinol therapy.
authors.affiliation: Department of Pediatrics, Saitama Medical School, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Morino
authors.forename: N
authors.initials: N
authors.lastname: Shiigai
authors.forename: H
authors.initials: H
authors.lastname: Kusuyama
authors.forename: K
authors.initials: K
authors.lastname: Okada
mesh_terms: D000493:Allopurinol / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007669:Kidney Calculi / Q000139:chemically induced* / Q000737:chemistry / Q000628:therapy; D007926:Lesch-Nyhan Syndrome / Q000188:drug therapy*; D008096:Lithotripsy; D008297:Male; D019820:Xanthine; D014970:Xanthines / Q000032:analysis*
chemical_list: D014970:Xanthines; D019820:Xanthine; D000493:Allopurinol