Horseshoe kidney and membranous glomerulonephritis with cold activation of complement.
A 48-year-old woman was admitted to our hospital because of proteinuria associated with persistent hypocomplementemia. Intravenous pyelography indicated the presence of horseshoe kidney without other abnormalities. Hypocomplementemia was caused by cold activation of complement. There were some findings suggestive of chronic liver disease (positive HCV antibody, hypergammaglobulinemia, low cholinesterase, etc.). Percutaneous renal biopsy showed the features of multiple evolutional phases of membranous glomerulonephritis.
Fujimoto
S
S
First Department of Internal Medicine, Miyazaki Medical College, Japan.
Hirayama
N
N
Uchida
T
T
Iemura
F
F
Yamamoto
Y
Y
Eto
T
T
Washimine
H
H
Sumiyoshi
A
A
D003080:Cold Temperature; D003167:Complement Activation; D005260:Female; D015433:Glomerulonephritis, Membranous / Q000276:immunology* / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000002:abnormalities*; D008854:Microscopy, Electron; D008875:Middle Aged