Spinal and trigeminal lamina I input to the locus coeruleus anterogradely labeled with Phaseolus vulgaris leucoagglutinin (PHA-L) in the cat and the monkey.
Terminal fibers anterogradely labeled with Phaseolus vulgaris leucoagglutinin (PHA-L) were observed in the locus coeruleus in the brainstem of the cat and the cynomolgus monkey following injections in lamina I of the spinal or medullary dorsal horn. Thus, thermoreceptive- or nociceptive-specific lamina I cells that project to the locus coeruleus could directly influence arousal, vigilance, and the descending control of spinal integration.
Craig
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Division of Neurobiology, Barrow Neurological Institute, Phoenix, AZ 85013.
D000818:Animals; D002415:Cats; D006651:Histocytochemistry; D006358:Hot Temperature; D008125:Locus Coeruleus / Q000502:physiology*; D008252:Macaca fascicularis; D009412:Nerve Fibers / Q000502:physiology; D009619:Nociceptors / Q000187:drug effects / Q000502:physiology; D010835:Phytohemagglutinins; D013116:Spinal Cord / Q000502:physiology*; D014276:Trigeminal Nerve / Q000166:cytology / Q000502:physiology*; D014966:Xanthenes
D010835:Phytohemagglutinins; D014966:Xanthenes; C100156:leukoagglutinins, plants; C034657:Texas red