title: Trisomy 8 and 11 in refractory anemia with excess blasts in transformation (RAEB-T).
abstract: There are no specific chromosomal abnormalities associated with refractory anemia with excess blasts in transformation [RAEB-T]. An 80-year-old white male with RAEB-T was found to have trisomies of chromosomes 8 and 11, i.e., 48,XY,+8,+11. To our knowledge, this chromosomal abnormality in RAEB-T has not been previously reported.
authors.affiliation: Division of Genetics, Long Island College Hospital, SUNY Health Science Center, Brooklyn 11201.
authors.forename: W R
authors.initials: WR
authors.lastname: Ramirez
authors.forename: C J
authors.initials: CJ
authors.lastname: Rosenthal
authors.forename: S K
authors.initials: SK
authors.lastname: Gogineni
authors.forename: R S
authors.initials: RS
authors.lastname: Verma
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000754:Anemia, Refractory, with Excess of Blasts / Q000235:genetics* / Q000628:therapy; D001803:Blood Transfusion; D002880:Chromosomes, Human, Pair 11; D002898:Chromosomes, Human, Pair 8; D006801:Humans; D007621:Karyotyping; D008297:Male; D014314:Trisomy