title: Effect of picroliv on protein and nucleic acid synthesis.
abstract: Oral administration of picroliv, a standardised fraction of roots and rhizomes of Picrorhiza kurroa, showed stimulation of nucleic acid and protein synthesis in rat liver. Results are comparable with a standard hepatoprotective agent, silymarin.
authors.affiliation: Biochemistry Division, Central Drug Research Institute, Lucknow, India.
authors.forename: V
authors.initials: V
authors.lastname: Singh
authors.forename: N K
authors.initials: NK
authors.lastname: Kapoor
authors.forename: B N
authors.initials: BN
authors.lastname: Dhawan
mesh_terms: D000818:Animals; D002934:Cinnamates / Q000494:pharmacology*; D006027:Glycosides / Q000494:pharmacology*; D008099:Liver / Q000378:metabolism; D008297:Male; D009696:Nucleic Acids / Q000096:biosynthesis* / Q000187:drug effects*; D010936:Plant Extracts / Q000494:pharmacology*; D014176:Protein Biosynthesis; D011506:Proteins / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains; D012838:Silymarin / Q000494:pharmacology; D014641:Vanillic Acid / Q000494:pharmacology*
chemical_list: D002934:Cinnamates; D006027:Glycosides; D009696:Nucleic Acids; D010936:Plant Extracts; D011506:Proteins; D012838:Silymarin; C057463:kutkin; D014641:Vanillic Acid