[Narcolepsy and alopecia areata: a new association?].
We here present three cases with Alopecia Areata and Narcolepsy, an association we believe to be hitherto undescribed. Narcolepsy is a low-frequency (0.5%) disorder. It is now accepted that the majority of patients with narcolepsy are DR2 positive. Alopecia Areata is a disease whose incidence in Caucasian population is between 0.05% and 1%. In both diseases there is a set of common data and the origins of the two diseases have been related to an autoimmunity mechanism. In both, a higher than normal incidence of diabetes has been recorded, together with a predominant HLA type pattern. We believe that this association is not casual although epidemiological studies are needed to test our working hypothesis.
Domínguez Ortega
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Servicio de Medicina Interna, Hospital 12 de Octubre, Universidad Complutense, Madrid.
D000293:Adolescent; D000328:Adult; D000506:Alopecia Areata / Q000150:complications* / Q000453:epidemiology; D004198:Disease Susceptibility; D005260:Female; D015234:HLA-A Antigens / Q000032:analysis; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009290:Narcolepsy / Q000150:complications* / Q000453:epidemiology; D015995:Prevalence
D015234:HLA-A Antigens
Narcolepsia y alopecia areata: una nueva asociación?