title: Drug delivery to the brain: barrier modification and drug modification methodologies.
authors.affiliation: Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892.
authors.forename: S I
authors.initials: SI
authors.lastname: Rapoport
mesh_terms: D000818:Animals; D001812:Blood-Brain Barrier; D001921:Brain / Q000378:metabolism*; D004058:Diffusion; D004337:Drug Carriers; D006801:Humans; D009997:Osmotic Pressure; D010539:Permeability; D010599:Pharmacokinetics; D012995:Solubility
chemical_list: D004337:Drug Carriers