Serum interleukin (IL-1 beta) in patients with diffuse scleritis.
Scleritis is a painful, destructive inflammatory eye disease. We measured serum IL-1 beta in ten patients with diffuse scleritis and in control subjects matched for age and sex. Patients with diffuse scleritis were found to have significantly elevated serum concentrations of IL-1 beta in comparison to normal subjects (P less than 0.02). The results suggest that IL-1 beta is associated with diffuse scleritis and may influence scleral breakdown in diffuse scleritis.
Palexas
G N
GN
Department of Ophthalmology, University of the Witwatersrand, Johannesburg, South Africa.
Puren
A
A
Savage
N
N
Welsh
N H
NH
D000328:Adult; D006801:Humans; D007375:Interleukin-1 / Q000097:blood*; D015423:Scleritis / Q000097:blood*
D007375:Interleukin-1