Neonatal alloimmune thrombocytopenia.
Neonatal alloimmune thrombocytopenia is caused by the transplacental passage of maternal antibodies directed against platelet-specific antigens. Because complications from bleeding may result, prompt institution of therapy may be necessary. Accurate diagnosis by serologic techniques permits appropriate therapy to be administered both prenatally and postnatally.
Kickler
T S
TS
Johns Hopkins Hospital Blood Bank, Johns Hopkins University School of Medicine, Baltimore, Maryland.
D016824:Antigens, Human Platelet / Q000276:immunology*; D016913:Blood Component Transfusion; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007519:Isoantigens / Q000276:immunology*; D011247:Pregnancy; D011296:Prenatal Diagnosis; D013921:Thrombocytopenia / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology* / Q000628:therapy
D016824:Antigens, Human Platelet; D007519:Isoantigens