title: BF and C3 genetic polymorphisms in Kaingang Indians from southern Brazil.
abstract: The distribution of C3 and BF variants was determined in a sample of 239 Kaingang Indians. The corresponding gene frequencies were as follows: BF*S = 0.9393, BF*F = 0.0356, BF*S05 = 0.0251, C3*S = 0.9769, C3*F = 0.0231. The presence of the BF*S05 allele, which has previously been found only in a Brazilian population, suggests that this allele originated in Amerindians. The comparatively low degree of polymorphism with high frequencies of BF*S and C3*S is in accordance with the relatedness of the Kaingang with other Amerindians, Eskimos and Asian populations.
authors.affiliation: Department of Clinical Pathology, University Hospital, Curitiba, Brazil.
authors.forename: L K
authors.initials: LK
authors.lastname: Guerra
authors.forename: I R
authors.initials: IR
authors.lastname: Rehfeldt
authors.forename: M T
authors.initials: MT
authors.lastname: Lima
authors.forename: M L
authors.initials: ML
authors.lastname: Petzl-Erler
authors.forename: I J
authors.initials: IJ
authors.lastname: de Messias
mesh_terms: D000483:Alleles; D001938:Brazil / Q000453:epidemiology; D003176:Complement C3 / Q000235:genetics*; D011415:Complement Factor B / Q000235:genetics*; D003165:Complement System Proteins / Q000235:genetics*; D006801:Humans; D007199:Indians, South American / Q000235:genetics*; D010641:Phenotype; D011110:Polymorphism, Genetic / Q000235:genetics*
chemical_list: D003176:Complement C3; D003165:Complement System Proteins; D011415:Complement Factor B