title: [Rhabdomyolysis due to simvastin. Apropos of a case with review of the literature].
abstract: A new case of simvastatin-induced acute rhabdomyolysis with heart failure after initiation of treatment with fusidic acid is reported. In most reported instances, statin treatment was initially well tolerated with muscle toxicity developing only after addition of another drug. The mechanism of this muscle toxicity is unelucidated but involvement of a decrease in tissue Co enzyme Q is strongly suspected.
authors.affiliation: Service de Clinique de Rhumatologie, C.H.U. Purpan, Toulouse.
authors.forename: C
authors.initials: C
authors.lastname: Dromer
authors.forename: C
authors.initials: C
authors.lastname: Vedrenne
authors.forename: T
authors.initials: T
authors.lastname: Billey
authors.forename: M
authors.initials: M
authors.lastname: Pages
authors.forename: B
authors.initials: B
authors.lastname: Fournié
authors.forename: A
authors.initials: A
authors.lastname: Fournié
mesh_terms: D000368:Aged; D000924:Anticholesteremic Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008148:Lovastatin / Q000009:adverse effects / Q000031:analogs & derivatives*; D012206:Rhabdomyolysis / Q000139:chemically induced*; D019821:Simvastatin
chemical_list: D000924:Anticholesteremic Agents; D008148:Lovastatin; D019821:Simvastatin
vernacular_title: Rhabdomyolyse à la simvastatine. A propos d'un cas avec revue de la littérature.