[Changes in thrombocytapheresis concentrations caused by leukocyte depletion with polyester filters].
We studied platelet loss, leukocyte depletion, T/B-cell-ratio, platelet morphology and platelet function (aggregation, hypotonic shock reaction, retention and retraction) prior to and after filtration through two different polyester filters (Sepacell PL-5A, Pall PL100) as well as the posttransfusional platelet increment 1 h after transfusion in 8 pairs of single donor platelet concentrates (Cobe Spectra, Fresenius AS 104). Leukocyte depletion was effective (greater than 99.9%) and platelet loss acceptable in both filters, all tests showing no indication of a diminished platelet function by filtration.
Weisbach
V
V
Abteilung Innere Medizin, Universitätsklinikum Rudolf Virchow, Freie Universität Berlin.
Riess
H
H
Gindi
N
N
Zeiler
T
T
Riewald
M
M
Zingsem
J
J
Eckstein
R
R
D006440:Hemofiltration / Q000295:instrumentation*; D006801:Humans; D007958:Leukocyte Count; D008212:Lymphocyte Depletion; D010976:Platelet Count; D010983:Plateletpheresis / Q000295:instrumentation*; D011091:Polyesters
D011091:Polyesters
Veränderungen an Thrombozytapheresekonzentraten durch Leukozytendepletion mit Polyesterfiltern.