title: Penicillin derived C2-symmetric dimers as novel inhibitors of HIV-1 proteinase.
authors.affiliation: Department of Medicinal Chemistry II, Glaxo Group Research Limited, Greenford, Middlesex, United Kingdom.
authors.forename: D C
authors.initials: DC
authors.lastname: Humber
authors.forename: N
authors.initials: N
authors.lastname: Cammack
authors.forename: J A
authors.initials: JA
authors.lastname: Coates
authors.forename: K N
authors.initials: KN
authors.lastname: Cobley
authors.forename: D C
authors.initials: DC
authors.lastname: Orr
authors.forename: R
authors.initials: R
authors.lastname: Storer
authors.forename: G G
authors.initials: GG
authors.lastname: Weingarten
authors.forename: M P
authors.initials: MP
authors.lastname: Weir
mesh_terms: D000998:Antiviral Agents / Q000494:pharmacology*; D002460:Cell Line; D003588:Cytopathogenic Effect, Viral / Q000187:drug effects; D004149:Dioxoles / Q000494:pharmacology* / Q000627:therapeutic use; D017320:HIV Protease Inhibitors; D015497:HIV-1 / Q000187:drug effects* / Q000201:enzymology / Q000502:physiology; D006801:Humans; D010406:Penicillins / Q000494:pharmacology*; D014779:Virus Replication / Q000187:drug effects; D014961:X-Ray Diffraction
chemical_list: D000998:Antiviral Agents; D004149:Dioxoles; D017320:HIV Protease Inhibitors; D010406:Penicillins; C076126:disodium (R,R)-5-(2-((2-(3-chlorophenyl)-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxole-2,3-dicarboxylate