title: TA-3037A, a new inhibitor of glutathione S-transferase, produced by actinomycetes. II. Structure determination.
abstract: TA-3037A, a new inhibitor of glutathione S-transferase, has been isolated from the culture broth of Streptomyces sp. TA-3037. The structure of TA-3037A was defined as (Z)-3-benzylidene-3,4-dihydro-2-oxo-2H-1,4-benzoxazine-5-carboxylic acid by an analysis of spectral properties and chemical studies of TA-3037A and its derivatives.
authors.affiliation: Institute of Microbial Chemistry, Tokyo, Japan.
authors.forename: D
authors.initials: D
authors.lastname: Komagata
authors.forename: Y
authors.initials: Y
authors.lastname: Muraoka
authors.forename: R
authors.initials: R
authors.lastname: Sawa
authors.forename: Y
authors.initials: Y
authors.lastname: Takahashi
authors.forename: H
authors.initials: H
authors.lastname: Naganawa
authors.forename: T
authors.initials: T
authors.lastname: Sawa
authors.forename: T
authors.initials: T
authors.lastname: Takeuchi
mesh_terms: D005982:Glutathione Transferase / Q000037:antagonists & inhibitors*; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D010078:Oxazines / Q000032:analysis / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D010078:Oxazines; C076479:TA 3037A; D005982:Glutathione Transferase