Presence of melanin in normal human Schwann cells.
The presence of melanin granules in Schwann cells of unmyelinated nerve fibres in the normal skin of a black woman is demonstrated by electron microscopy. Pathological conditions associated with the differentiation ability of Schwann cells for melanogenic are reviewed. This capacity may be due to the common origin of Schwann cells and melanocytes in the neural crest.
Carbonell
A L
AL
Department of Histology and General Embryology, Faculty of Medicine, University Complutense, Madrid, Spain.
Boya
J
J
García-Mauriño
J E
JE
D006801:Humans; D008543:Melanins / Q000378:metabolism*; D008854:Microscopy, Electron; D009412:Nerve Fibers / Q000378:metabolism / Q000648:ultrastructure; D012583:Schwann Cells / Q000378:metabolism* / Q000648:ultrastructure; D012867:Skin / Q000294:innervation / Q000378:metabolism / Q000648:ultrastructure
D008543:Melanins