title: Non-invasive thermometry with multi-frequency microwave radiometry.
abstract: The present status of the development of a non-invasive thermometer based on microwave radiometry at our laboratory is reported. We have developed a model fitting technique combined with a Monte Carlo technique to retrieve temperature-depth profiles from multi (4-6)-frequency-band microwave radiometric data along with confidence intervals (2-sigma) of tissue temperatures as a function of depth. In order to make the radiometric technique compatible with the heating, brightness temperatures are measured through a 1 cm thick water bolus. Results of phantom experiments are presented to demonstrate the above capabilities of the method. Numerical simulation studies have shown that 2-sigma intervals would be 1.0 K or less over a 0-4 cm range and 1.4 K at 5 cm from the surface with using a six-band, 1-5 GHz radiometer having brightness temperature resolution of 0.03 K (3 s integration time). The six-band instrument is currently being assembled at our laboratory.
authors.affiliation: Research Institute of Electronics, Shizuoka University, Hamamatsu, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Mizushina
authors.forename: T
authors.initials: T
authors.lastname: Shimizu
authors.forename: T
authors.initials: T
authors.lastname: Sugiura
mesh_terms: D001831:Body Temperature; D001943:Breast Neoplasms / Q000188:drug therapy; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D008433:Mathematics; D008872:Microwaves; D008954:Models, Biological; D008991:Monitoring, Physiologic / Q000379:methods; D009010:Monte Carlo Method; D013821:Thermometers