Necrotizing arteritis in uncorrected tetralogy of Fallot with pulmonary artery.
A 10-year-old girl with uncorrected tetralogy of Fallot with pulmonary atresia presented with fevers of unknown origin and left lung infiltrates. At autopsy, necrotizing vascular changes resembling those of severe pulmonary hypertension (grade VI in the Health-Edwards classification) were confined to the left lung. Pulmonary blood flow and pressure were greater in the left lung and were provided by an enlarged collateral artery arising directly from the descending thoracic aorta. To our knowledge, this is the first report of necrotizing arteritis of the pulmonary arteries in uncorrected tetralogy of Fallot with pulmonary atresia.
Andriko
J A
JA
Department of Pathology, Walter Reed Army Medical Center, Washington, D.C.
Robinowitz
M
M
Moore
J
J
Virmani
R
R
D001167:Arteritis / Q000209:etiology* / Q000473:pathology; D002648:Child; D005260:Female; D005335:Fever of Unknown Origin / Q000209:etiology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology* / Q000473:pathology; D011651:Pulmonary Artery / Q000002:abnormalities*; D013771:Tetralogy of Fallot / Q000150:complications* / Q000473:pathology