[Characteristics of the effect of irradiation at different dose rates on survival, death kinetics and response of critical systems of the C57Bl/6 mice].
A comparison was made of the biological effect on mice of irradiation at different dose rates (70, 5.5 and 1.5 cGy/min) with equally effective, with respect to lethality, doses, or with physically equal doses within the range from 1/4 of LD50/30 to LD99-95/30. Equally effective, with respect to lethality, doses caused similar changes in the intestinal epithelium and in the haemopoietic system. The death rate kinetics was identical with doses of LD80-95/30 within the dose-rate range under study. The equally effective doses caused injuries, different in degrees, to critical systems, including CFUs.
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D000818:Animals; D001853:Bone Marrow / Q000528:radiation effects; D004848:Epithelium / Q000528:radiation effects; D005260:Female; D006413:Hematopoietic System / Q000528:radiation effects*; D007422:Intestines / Q000528:radiation effects*; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D011829:Radiation Dosage; D013154:Spleen / Q000528:radiation effects; D013234:Stem Cells / Q000528:radiation effects*
Osobennosti deĭstviia oblucheniia s razlichnoĭ moshchnost'iu dozy na vyzhivaemost', kinetiku gibeli i reaktsiiu kriticheskikh sistem u mysheĭ C57Bl/6.