title: Disease patterns of patients with systemic lupus erythematosus as shown by application of factor analysis.
abstract: Clinical and laboratory test data of 77 patients with systemic lupus erythematosus (SLE) were evaluated by factor analysis. Six factors representing disease patterns were extracted: cutaneous symptoms of alopecia, malar rash, rash and photosensitivity; renal involvement; the anticoagulant syndrome of phlebitis and partial thromboplastic time inversely related to platelet count; lymphopenia; viral or fibromyalgia symptoms of headache, nervousness, joint and muscle pain; and serology of anti-DNA antibodies and complement inversely related. Application of factor analysis reveals various clinical presentations of SLE.
authors.affiliation: Rheumatology Unit, Beilinson Medical Center, Petah Tiqva, Israel.
authors.forename: A J
authors.initials: AJ
authors.lastname: Wysenbeek
authors.forename: L
authors.initials: L
authors.lastname: Leibovici
authors.forename: M
authors.initials: M
authors.lastname: Amit
authors.forename: A
authors.initials: A
authors.lastname: Weinberger
mesh_terms: D000328:Adult; D000368:Aged; D000505:Alopecia / Q000453:epidemiology; D000974:Antibodies, Antinuclear / Q000032:analysis; D005163:Factor Analysis, Statistical; D005260:Female; D006261:Headache / Q000453:epidemiology; D006801:Humans; D007592:Joint Diseases / Q000453:epidemiology; D007674:Kidney Diseases / Q000453:epidemiology; D008180:Lupus Erythematosus, Systemic / Q000453:epidemiology*; D008231:Lymphopenia / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010314:Partial Thromboplastin Time; D010689:Phlebitis / Q000453:epidemiology; D010787:Photosensitivity Disorders / Q000453:epidemiology
chemical_list: D000974:Antibodies, Antinuclear