[Analysis of hepatocyte cell membrane antigens in regenerating rat liver].
Antigens of plasma membranes in hepatocytes from regenerating rat liver were studied. Immunochemical investigation with polyvalent rabbits antiserum against plasma membrane proteins in hepatocytes from regenerating and normal rat liver have shown that liver regeneration processes are accompanied by the increase of proteins number with molecular weight of--80 kDa, 62 kDa, 40 kDa and 27 kDa. It is not excluded that protein with molecular weight of 27 kDa is the tissue-specific peripheral protein. The influence of antibodies against proteins of hepatocytes plasmatic membranes on histostructure of pathologically changed liver tissue has been studied. The data obtained testify to a possibility of participation of the above mentioned proteins in the regulation of rat liver regeneration processes.
Nikolaenko
A N
AN
Pavlovich
S I
SI
Ivanov
A P
AP
Alekseeva
I N
IN
Shorokh
D B
DB
Makogon
N V
NV
D000818:Animals; D000941:Antigens / Q000032:analysis*; D002462:Cell Membrane / Q000276:immunology; D004591:Electrophoresis, Polyacrylamide Gel; D007150:Immunohistochemistry; D008099:Liver / Q000166:cytology / Q000276:immunology*; D008115:Liver Regeneration / Q000276:immunology*; D008297:Male; D008565:Membrane Proteins / Q000276:immunology; D051381:Rats
D000941:Antigens; D008565:Membrane Proteins
Analiz antigenov plazmaticheskikh membran gepatotsitov regeneriruiushcheĭ pecheni krys.