Distribution of neuropeptide Y-like immunoreactivity in the brain of Salmo salar and Gambusia affinis.
Through the immunohistochemical PAP technique, the distribution of immune positive neurons and fibres for an antibody anti-NPY in the encephalon of salmon fixed in Bouin have been located and studied. NPY-positive neurons are found forming three important nuclei: in the ventrolateral telencephalon; in the tegmentum mesencephali; and in the locus coeruleus. Neurons in the optic tectum, in the thalamic region and a few in the preoptic recess have also been located. The fibres were found throughout the brain, with the exception of the cerebellum, presenting a greater density in three regions: in the dorsal telencephalon; in the mesencephalon; and in the visceral lobes in the rhombencephalon. With the aim of proving if this distribution is found in other groups of teleosts, we processed, with the same technique, the advanced teleost Gambusia affinis, in order to compare it with the primitive teleost Salmo salar. The results show that in both fish this neuropeptide has the same pattern of distribution. The results also suggest that in fish this neuropeptide can be involved in several functions of the central nervous system, as has been demonstrated for mammals. The innervation of the visceral lobes and also the presence of NPY-fibres in the posterior hypothalamus are anatomical supports of the studies which suggest that NPY is related to the control of the food intake.
García-Fernández
J M
JM
Department of Morphology and Cellular Biology, Oviedo University, Spain.
del Brío
M A
MA
Cernuda
R
R
Coto
A
A
Riera
P
P
D000818:Animals; D001921:Brain / Q000378:metabolism*; D001933:Brain Stem / Q000378:metabolism; D003532:Cyprinodontiformes / Q000378:metabolism*; D004027:Diencephalon / Q000378:metabolism; D007150:Immunohistochemistry; D008636:Mesencephalon / Q000378:metabolism; D009478:Neuropeptide Y / Q000378:metabolism*; D012474:Salmon / Q000378:metabolism*; D013045:Species Specificity; D013687:Telencephalon / Q000378:metabolism; D014018:Tissue Distribution
D009478:Neuropeptide Y