title: Comparison of fiberendoscopy and Watson capsule for small intestinal biopsy in infants and children.
abstract: We analyzed the results of 607 small bowel biopsies performed over a seven-year period: 284 biopsies were obtained using a fiberendoscope and 323 biopsies using a Watson capsule. Three to six specimens were removed during endoscopy. The biopsy fragments obtained with the fiberendoscope were deeper than those obtained with the Watson capsule (p less than 0.0001) and were more often located in the duodenum (p less than 0.0001). The failure rate of the fiberendoscope biopsies (1%) was lower than for the Watson capsule biopsies (9%) (p less than 0.0001). Multiple biopsies increased the diagnostic value of fiberendoscopy which was 95% versus 85% for Watson capsule. The mean duration of the endoscopic procedure recorded in 30 children was 6.5 min for four to six samples, i.e. 1.5 min per biopsy specimen. Fiberendoscopy appears to be an efficient and safe method for performing small bowel biopsies in infants and children.
authors.affiliation: Service de Pédiatrie, Gastroentérologie Pédiatrique et Génétique Médicale, Hôpital Claude Huriez, Lille, France.
authors.forename: F
authors.initials: F
authors.lastname: Gottrand
authors.forename: D
authors.initials: D
authors.lastname: Turck
authors.forename: V
authors.initials: V
authors.lastname: Mitchell
authors.forename: J P
authors.initials: JP
authors.lastname: Farriaux
mesh_terms: D000293:Adolescent; D001706:Biopsy / Q000379:methods; D002648:Child; D002675:Child, Preschool; D016099:Endoscopy, Gastrointestinal / Q000379:methods*; D005336:Fiber Optic Technology; D006801:Humans; D007223:Infant; D007421:Intestine, Small / Q000473:pathology*; D012189:Retrospective Studies; D013997:Time Factors