Identification of neuron subpopulations in the rat vestibular ganglion by calbindin-D 28K, calretinin and neurofilament proteins immunoreactivity.
Immunocytochemical and morphometric analyses were combined to demonstrate the presence of neuron subpopulations in the rat vestibular ganglion. Monoclonal antibodies reacting with neurofilament proteins (NF), calbindin-D 28K (CaBP) and calretinin (CaR) were used. Three subpopulations were identified: (1) CaBP- and CaR-positive neurons were the largest neurons (16%) and they were also highly NF-immunoreactive; (2) exclusively NF-positive neurons; (3) unlabelled neurons, representing about two-thirds of the population.
Demêmes
D
D
INSERM U 254, Laboratoire de Neurophysiologie Sensorielle, USTL, Montpellier, France.
Raymond
J
J
Atger
P
P
Grill
C
C
Winsky
L
L
Dechesne
C J
CJ
D000818:Animals; D000911:Antibodies, Monoclonal; D064032:Calbindin 2; D064026:Calbindins; D005455:Fluorescent Antibody Technique; D007124:Immunoenzyme Techniques; D008297:Male; D009419:Nerve Tissue Proteins / Q000032:analysis; D016900:Neurofilament Proteins / Q000032:analysis*; D009474:Neurons / Q000166:cytology*; D051381:Rats; D064030:S100 Calcium Binding Protein G / Q000032:analysis*; D014725:Vestibular Nerve / Q000166:cytology*
D000911:Antibodies, Monoclonal; C576512:Calb2 protein, rat; D064032:Calbindin 2; D064026:Calbindins; D009419:Nerve Tissue Proteins; D016900:Neurofilament Proteins; D064030:S100 Calcium Binding Protein G