Comparison of the MEASLESTAT M test kit with the sucrose density gradient centrifugation-hemagglutination inhibition method for detection of measles virus-specific immunoglobulin M.
A new commercial kit, MEASLESTAT M (Whittaker Bioproducts, Inc.), was compared with the sucrose density gradient centrifugation-hemagglutination inhibition method for the detection of measles virus-specific immunoglobulin M. Overall agreement between the two procedures was 97.1% for 104 single and paired serum samples tested. The sensitivity and specificity of MEASLESTAT M were 98.4 and 95.2%, respectively.
Withers
G S
GS
Bureau of Laboratories, Pennsylvania Department of Health, Lionville 19353.
Sweimler
W I
WI
Kleger
B
B
D000914:Antibodies, Viral / Q000097:blood*; D001431:Bacteriological Techniques; D002499:Centrifugation, Density Gradient; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005069:Evaluation Studies as Topic; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood*; D008457:Measles / Q000175:diagnosis / Q000276:immunology; D008459:Measles virus / Q000276:immunology*
D000914:Antibodies, Viral; D007075:Immunoglobulin M