Juvenile chronic myelocytic leukemia with unusual cytogenetic clonal evolution.
Cytogenetic studies are reported in a case of juvenile chronic myelocytic leukemia with dysmyelopoiesis and skin involvement. The clonal evolution of a 6q-anomaly is described. Hematological and cytogenetic findings suggest a role of hematopoietic stem cell in this patient for whom the outcome was fatal.
Eclache
V
V
Laboratoire d'Hématologie, Hôpital Avicenne, Bobigny, France.
Van den Akker
J
J
Perot
C
C
Taillemite
J L
JL
Nathanson
M
M
Leverger
G
G
Lortholary
P
P
D002675:Child, Preschool; D002999:Clone Cells / Q000502:physiology; D005260:Female; D006801:Humans; D007621:Karyotyping; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000235:genetics*