title: Age-related remodeling of lobster neuromuscular terminals.
abstract: Multiterminal innervation of a lobster limb muscle by an identified excitor motoneuron was examined during primary development and adult growth. To keep pace with the growth in the target muscle, axonal branches proliferate by sprouting from synaptic terminals; an increasingly complex branching pattern results. Neuromuscular synapses multiply in number, enlarge in size, and become perforated. Concomitantly, synapses tend to appear on the more distal axonal branches and to disappear on more proximal branches, providing for continual remodeling of multiterminal innervation. This plasticity in an identified motoneuron occurs over a long life span of several decades.
authors.affiliation: Life Sciences Division, Scarborough College, University of Toronto, Ontario, Canada.
authors.forename: C K
authors.initials: CK
authors.lastname: Govind
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D001369:Axons / Q000502:physiology; D008121:Nephropidae / Q000033:anatomy & histology / Q000502:physiology*; D009411:Nerve Endings / Q000502:physiology* / Q000648:ultrastructure; D009469:Neuromuscular Junction / Q000502:physiology* / Q000648:ultrastructure; D009473:Neuronal Plasticity; D013569:Synapses / Q000502:physiology