Estrogen receptors are present in neocortical transplants.
Fetal neocortical tissue was grafted into neocortical lesion cavities made in newborn rats. After two weeks survival, in vitro binding of [3H]-estradiol to cytosolic preparations provided evidence of estrogen receptors within the transplants. The observed high levels correspond to previous work demonstrating elevated estrogen receptor levels during the first postnatal week in the rat cerebral cortex.
Pedersen
E B
EB
Department of Cell Biology, Neurobiology and Anatomy, Loyola University Stritch School of Medicine, Maywood, IL 60153.
O'Keefe
J A
JA
Handa
R J
RJ
Castro
A J
AJ
D000818:Animals; D000831:Animals, Newborn / Q000502:physiology; D016380:Brain Tissue Transplantation / Q000502:physiology*; D002540:Cerebral Cortex / Q000187:drug effects / Q000502:physiology* / Q000637:transplantation; D003600:Cytosol / Q000378:metabolism; D016332:Fetal Tissue Transplantation / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D011960:Receptors, Estrogen / Q000187:drug effects*; D014184:Transplantation, Homologous
D011960:Receptors, Estrogen