title: The white cell count in typhoid fever.
abstract: Leucopenia with neutropenia and a relative lymphocytosis are believed to be common findings in patients with typhoid fever. This paper reviews 191 adult patients with typhoid. The total and differential leucocyte counts done on admission were analysed. In this study leucopenia was found in only 24.6% of patients. Whilst complications occurred at any white cell count, the prevalence of complications increased significantly to 70% in patients with a white cell count above 8 x 10(9)/l. Neutropenia was found in 25% of patients, and none of the patients had an absolute lymphocytosis, whereas 75.8% of patients had true lymphopenia.
authors.affiliation: Department of Medicine, Faculty of Medicine, University of Natal/King Edward Hospital, Durban, South Africa.
authors.forename: M S
authors.initials: MS
authors.lastname: Abdool Gaffar
authors.forename: Y K
authors.initials: YK
authors.lastname: Seedat
authors.forename: Y M
authors.initials: YM
authors.lastname: Coovadia
authors.forename: Q
authors.initials: Q
authors.lastname: Khan
mesh_terms: D000328:Adult; D005260:Female; D006785:Hospitals, University; D006801:Humans; D007958:Leukocyte Count; D007970:Leukopenia / Q000097:blood* / Q000453:epidemiology / Q000209:etiology; D008231:Lymphopenia / Q000097:blood* / Q000453:epidemiology / Q000209:etiology; D008297:Male; D009503:Neutropenia / Q000097:blood* / Q000453:epidemiology / Q000209:etiology; D015995:Prevalence; D012189:Retrospective Studies; D013019:South Africa / Q000453:epidemiology; D014435:Typhoid Fever / Q000150:complications* / Q000401:mortality