title: [Perioperative hemostatic problems in children].
abstract: During childhood preoperative coagulation diagnosis is performed to prove or to rule out an inborn coagulation disorder or an acquired v. Willebrand disease. The coagulation system of the newborns differs considerably from that of the adults as well as the time in which the single parameters reach adult values. Reducing the coagulation screening to the determination of aPTT and Quicktest neglects severe hemostaseological disorders easily, e.g. v. Willebrand disease which often in childhood is to be observed and often combined with normal aPTT values. Probably sometimes children affected with hypertrophy of the adenoids have temporary aPTT prolongations combined with normal values for the other coagulation parameters possibly due to lupus inhibitors. When children with deficiencies of coagulation factors need high doses of coagulation concentrates the number of laboratory controls may be reduced by determination on recovery and half-life period some times before.
authors.affiliation: Univ.-Kinderklinik Würzburg.
authors.forename: A M
authors.initials: AM
authors.lastname: Mingers
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001778:Blood Coagulation Disorders / Q000097:blood* / Q000517:prevention & control; D001780:Blood Coagulation Tests; D002648:Child; D002675:Child, Preschool; D003955:Diagnostic Tests, Routine; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000097:blood / Q000517:prevention & control; D008297:Male; D011183:Postoperative Complications / Q000097:blood* / Q000517:prevention & control; D012016:Reference Values
vernacular_title: Perioperative Gerinnungsprobleme bei Kindern.