title: Fox-Fordyce disease: successful treatment with topical clindamycin in alcoholic propylene glycol solution.
abstract: We report a 66-year-old woman with a 3-year history of intensely pruritic follicular papules in the axillar, pubic and inguinal areas. Previous treatment with topical fusidic acid and gentamicin sulfate was ineffective. The clinical and histological examination was consistent with Fox-Fordyce disease. Application of clindamycin in an alcoholic propylene glycol solution led to the clearing of the lesions within 1 month. Nine months later, the treatment was stopped, and no recurrence was observed.
authors.affiliation: Department of Dermatology, University Hospital, Geneva, Switzerland.
authors.forename: R
authors.initials: R
authors.lastname: Feldmann
authors.forename: I
authors.initials: I
authors.lastname: Masouyé
authors.forename: P
authors.initials: P
authors.lastname: Chavaz
authors.forename: J H
authors.initials: JH
authors.lastname: Saurat
mesh_terms: D000433:1-Propanol / Q000008:administration & dosage / Q000627:therapeutic use*; D000287:Administration, Topical; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000627:therapeutic use*; D002981:Clindamycin / Q000008:administration & dosage / Q000627:therapeutic use*; D004338:Drug Combinations; D005260:Female; D005588:Fox-Fordyce Disease / Q000188:drug therapy*; D006801:Humans; D019946:Propylene Glycol; D011409:Propylene Glycols / Q000008:administration & dosage / Q000627:therapeutic use*; D012996:Solutions
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D004338:Drug Combinations; D011409:Propylene Glycols; D012996:Solutions; D002981:Clindamycin; D019946:Propylene Glycol; D000433:1-Propanol