title: Preimplantation genetic analysis.
abstract: Advanced reproductive technologies have afforded us access to human preembryos, allowing the possibility of preimplantation genetic diagnosis of certain genetic diseases. This paper thoroughly reviews both the micro-manipulation and molecular biologic aspects of this new and exciting branch of medicine. In addition, some of the moral and ethical considerations relating to preembryo genetic diagnosis are discussed.
authors.affiliation: Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk 23510.
authors.forename: R A
authors.initials: RA
authors.lastname: Kaufmann
authors.forename: M
authors.initials: M
authors.lastname: Morsy
authors.forename: K
authors.initials: K
authors.lastname: Takeuchi
authors.forename: G D
authors.initials: GD
authors.lastname: Hodgen
mesh_terms: D001706:Biopsy; D015925:Cryopreservation / Q000379:methods / Q000592:standards; D004247:DNA; D047108:Embryonic Development; D004992:Ethics, Medical; D005260:Female; D005307:Fertilization in Vitro; D005820:Genetic Testing / Q000379:methods* / Q000592:standards; D006801:Humans; D009693:Nucleic Acid Hybridization; D015345:Oligonucleotide Probes; D016133:Polymerase Chain Reaction; D011247:Pregnancy
chemical_list: D015345:Oligonucleotide Probes; D004247:DNA