title: The basic neurobiology of addiction.
abstract: This overview on cocaine's addiction liability is presented in this monograph on the blood-brain barrier (BBB) because the National Institute on Drug Abuse has been given the task of finding pharmacotherapies to treat addiction. Knowledge about the BBB might help researchers design better drugs or approaches to keep the "good" drugs inside and/or the "bad" drugs outside. It is to be hoped that the BBB community can be convinced that drug abuse is an exciting area and that work on biological barriers has something to offer.
authors.affiliation: Neuroscience Branch, National Institute on Drug Abuse, Rockville, MD 20857.
authors.forename: R M
authors.initials: RM
authors.lastname: Brown
mesh_terms: D001812:Blood-Brain Barrier; D001921:Brain / Q000187:drug effects; D003042:Cocaine / Q000009:adverse effects*; D006801:Humans; D012201:Reward; D019966:Substance-Related Disorders / Q000209:etiology*
chemical_list: D003042:Cocaine