title: Effect of different agonistic experiences on behavioural seizures in fully amygdala kindled rats.
abstract: Fully amygdala kindled rats were exposed to two different inter-male agonistic experiences in order to study the interaction between epilepsy and acute social stress. Victory experience did not influence the severity of seizure behaviour, whereas a single acute defeat modified both ictal and postictal seizure manifestations. Defeat resulted in less severe and shorter lasting motor seizures, and the accompanied postictal inhibition or behavioural depression was of shorter duration in comparison with pre-stress values. The ability of acute defeat to trigger anticonvulsant activity as implied by the weakened convulsive response is discussed.
authors.affiliation: Department of Animal Physiology, University of Groningen, Haren, Netherlands.
authors.forename: H J
authors.initials: HJ
authors.lastname: Beldhuis
authors.forename: J M
authors.initials: JM
authors.lastname: Koolhaas
authors.forename: B
authors.initials: B
authors.lastname: Bohus
mesh_terms: D000378:Agonistic Behavior / Q000502:physiology*; D000679:Amygdala / Q000502:physiology*; D000818:Animals; D001522:Behavior, Animal / Q000502:physiology*; D007696:Kindling, Neurologic / Q000502:physiology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012640:Seizures / Q000503:physiopathology*; D012919:Social Behavior; D013315:Stress, Psychological / Q000523:psychology