Bioactive peptides and serotonin in the gut endocrine cells of the crocodile, Crocodylus niloticus (Laurenti 1768): an immunocytochemical study.
Little is known about peptide-storing endocrine cells in the gut of the Nile crocodile. As in the case of other reptiles, particularly the alligator, a limited range of peptide-storing cells was found in the gut of the crocodile. They were somatostatin, glucagon, gastrin, neurotensin and pancreatic polypeptide. The topographical distribution of cells immunoreactive to somatostatin and gastrin in the gut of the crocodile is comparable to the situation in the alligator. Glucagon and neurotensin immunoreactive cells have a much wider distribution in the gastro-intestinal tract of the crocodile compared to the alligator. Cholecystokinin and bombesin cells previously reported in the small intestine of the alligator were not detected in this study. This is the first report to demonstrate pancreatic polypeptide and serotonin immunoreactivity in the gut of a crocodilian specie.
Van Aswegen
G
G
Department of Anatomy, Potchefstroom University for Christian Higher Education, South Africa.
Kotzé
S H
SH
van der Merwe
N J
NJ
Smith
G A
GA
D000489:Alligators and Crocodiles / Q000378:metabolism*; D000818:Animals; D004064:Digestive System / Q000737:chemistry*; D005755:Gastrins / Q000032:analysis; D005934:Glucagon / Q000032:analysis; D007150:Immunohistochemistry; D009479:Neuropeptides / Q000032:analysis*; D009496:Neurotensin / Q000032:analysis; D010191:Pancreatic Polypeptide / Q000032:analysis; D012701:Serotonin / Q000302:isolation & purification*
D005755:Gastrins; D009479:Neuropeptides; D012701:Serotonin; D009496:Neurotensin; D010191:Pancreatic Polypeptide; D005934:Glucagon