Long-term undiagnosed syphilis with clinical presentation of meningitis.
A 43-year-old woman, with an 11-year history of progressive cutaneous lesions, was considered to have granuloma annulare and was treated as such for 4 years. She then developed chronic meningitis. Serological investigation revealed active syphilis. Appropriate antibiotic treatment led to a rapid resolution of the clinical symptoms. The recent reports of similar cases indicate the importance of an adequate knowledge of clinical manifestations and pathological patterns of syphilis.
Pizarro
A
A
Dermatology Service, La Paz Hospital, Madrid, Spain.
Fonseca
E
E
Anciones
B
B
Lara
M
M
Contreras
F
F
D000328:Adult; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005260:Female; D016460:Granuloma Annulare / Q000175:diagnosis*; D006801:Humans; D016920:Meningitis, Bacterial / Q000175:diagnosis*; D009494:Neurosyphilis / Q000175:diagnosis*; D012874:Skin Diseases, Infectious / Q000175:diagnosis*; D013587:Syphilis / Q000175:diagnosis*