PI*E Tripoli: a new allele in the alpha-1-antitrypsin system.
Genetic variants of the human serum alpha 1-antitrypsin (PI system) were analyzed in a population sample of 110 unrelated Libyans. Four common PI M variants and 3 rare ones, including a new anodal variant designated PI E Tripoli (PI ET) were identified. The estimated allele frequencies were: PI*M1 = 0.623; PI*M2 = 0.205; PI*M3 = 0.132; PI*M4 = 0.018; PI*ET = 0.005; PI*S = 0.005, and PI*T = 0.014.
Sebetan
I M
IM
Department of Laboratory Medicine and Pathology, Hamad General Hospital, Doha, Qatar.
D000483:Alleles; D006801:Humans; D008002:Libya / Q000453:epidemiology; D010641:Phenotype; D011110:Polymorphism, Genetic / Q000235:genetics*; D000515:alpha 1-Antitrypsin / Q000235:genetics*
D000515:alpha 1-Antitrypsin