title: Sickle-cell anemia: a case report and literature review.
abstract: Sickle-cell disease is characterized by the pathophysiological features of chronic hemolytic anemia, vaso-occlusion resulting in ischemic tissue injury and painful episodes. The organs at greatest risk are the spleen, kidney and bone marrow, where oxygen tension is low and blood flow is diminished. However, disease may also present in the mandible. The oral manifestations and radiographic findings of a sickle cell patient with a left mandibular neuropathy, along with dental management guidelines are presented in the context of interdisciplinary care.
authors.affiliation: National Institute of Dental Research, Bethesda.
authors.forename: G
authors.initials: G
authors.lastname: Cherry-Peppers
authors.forename: V
authors.initials: V
authors.lastname: Davis
authors.forename: J C
authors.initials: JC
authors.lastname: Atkinson
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000175:diagnosis / Q000503:physiopathology; D005157:Facial Pain / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008336:Mandibular Diseases / Q000000981:diagnostic imaging*; D011859:Radiography