title: Warfarin-induced complete bilateral breast necrosis.
abstract: Plastic surgeons are routinely consulted about the care of extended cutaneous necrosis. We present an unusual case of complete bilateral breast necrosis and review of the literature of warfarin-induced necrosis to inform plastic surgeons of new advances in the physiopathology of this entity. Warfarin-induced necrosis seems to be produced by an imbalance between circulating clotting factors and blood anticoagulation factors.
authors.affiliation: Department of Plastic Surgery, Saint-Sacrement Hospital, Quebec, Canada.
authors.forename: C A
authors.initials: CA
authors.lastname: López Valle
authors.forename: G
authors.initials: G
authors.lastname: Hébert
mesh_terms: D001777:Blood Coagulation / Q000502:physiology; D001779:Blood Coagulation Factors / Q000032:analysis; D001940:Breast / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009336:Necrosis; D014859:Warfarin / Q000009:adverse effects*
chemical_list: D001779:Blood Coagulation Factors; D014859:Warfarin