title: Central neurocytoma presenting with gigantism: case report.
abstract: We report a case of central neurocytoma presenting with gigantism. The patient was a 19-year-old man with a 2-year history of rapid growth. Computed tomography revealed a round, slightly enhancing calcified tumor in the septal region. This lesion was resected, and postoperative radiotherapy was given. The preoperative serum growth hormone level was 20.7 ng/mL, and postoperatively this fell to 0.9 ng/mL. Pituitary dysfunction was not noted either before or after the operation. A low level of production of growth hormone releasing factor was detected when tumor cells obtained during surgery were cultured.
authors.affiliation: Department of Neurosurgery, Gifu University School of Medicine, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Araki
authors.forename: N
authors.initials: N
authors.lastname: Sakai
authors.forename: T
authors.initials: T
authors.lastname: Andoh
authors.forename: S
authors.initials: S
authors.lastname: Yoshimura
authors.forename: H
authors.initials: H
authors.lastname: Yamada
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism / Q000601:surgery; D005877:Gigantism / Q000209:etiology* / Q000378:metabolism; D006801:Humans; D008297:Male; D009447:Neuroblastoma / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism / Q000601:surgery; D010907:Pituitary Hormones / Q000378:metabolism
chemical_list: D010907:Pituitary Hormones