title: Intestinal fibrosis with partial obstruction in five horses and two ponies.
abstract: Fibrosis of the small intestine led to recurrent colic and weight loss in 2 ponies and 5 horses. There was a reduction in the length of the small intestine to one-half normal in horses 4 to 7. Histologic examination revealed substantial small intestinal submucosal fibrosis and arteriole sclerosis. The cause was not determined, but an environmental factor was suspected because 3 horses were from the same farm and the other animals were from within a 10-mile radius of the farm. The submucosal fibrosis appeared to be secondary to sclerosis of arterioles in the submucosa and mesentery, with low blood flow state or altered vessel permeability.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523.
authors.forename: J L
authors.initials: JL
authors.lastname: Traub-Dargatz
authors.forename: P C
authors.initials: PC
authors.lastname: Schultheiss
authors.forename: M L
authors.initials: ML
authors.lastname: Kiper
authors.forename: T S
authors.initials: TS
authors.lastname: Stashak
authors.forename: R
authors.initials: R
authors.lastname: Wrigley
authors.forename: J
authors.initials: J
authors.lastname: Schlipf
authors.forename: F M
authors.initials: FM
authors.lastname: Applehans
mesh_terms: D015746:Abdominal Pain / Q000209:etiology / Q000662:veterinary; D000818:Animals; D001160:Arterioles / Q000473:pathology; D001161:Arteriosclerosis / Q000209:etiology / Q000473:pathology / Q000662:veterinary; D005260:Female; D005355:Fibrosis; D006734:Horse Diseases / Q000209:etiology* / Q000473:pathology; D006736:Horses; D007415:Intestinal Obstruction / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D007421:Intestine, Small / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology*; D007583:Jejunum / Q000098:blood supply / Q000473:pathology; D008297:Male; D012008:Recurrence; D014463:Ultrasonography; D015431:Weight Loss