title: Localization of Lom-AG-myotropin I-like substances in the male reproductive and nervous tissue of the locust, Locusta migratoria.
abstract: Lom-AG myotropin I (Lom-AG-MTI) was the first peptide to be isolated from the male accessory reproductive glands of the locust, Locust migratoria. It shows no sequence similarity to any of the peptides identified from vertebrate or invertebrate tissues. A polyclonal antiserum was used to localize Lom-AG-MTI-like material in the male reproductive system and nervous system of the locust. Immunoreactivity was found in two of the hyaline gland tubules. In the brain, cell bodies were detected in the photo- and deuterocerebrum as well as the frontal ganglion. Nerve fibers were stained in the neuropils of the brain and throughout the labial nerves into the recurrent nerve. Thoracic and last abdominal ganglia contained neurons which could be stained with Lom-AG-MTI antiserum. The pronounced reactivity in the central nervous system suggests a possible neuroregulatory function of the peptide.
authors.affiliation: Zoological Institute, University of Leuven, Belgium.
authors.forename: L
authors.initials: L
authors.lastname: Paemen
authors.forename: L
authors.initials: L
authors.lastname: Schoofs
authors.forename: A
authors.initials: A
authors.lastname: De Loof
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D005837:Genitalia, Male / Q000033:anatomy & histology / Q000737:chemistry*; D006110:Grasshoppers / Q000033:anatomy & histology / Q000737:chemistry*; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D009420:Nervous System / Q000033:anatomy & histology / Q000737:chemistry*; D009479:Neuropeptides / Q000032:analysis*
chemical_list: D009479:Neuropeptides; C068978:Lom-AG-myotropin