In human monocytes IL-1 stimulates a phospholipase C active on phosphatidylcholine and inactive on phosphatidylinositol.
Galella
G
G
Institute of Pharmacological Sciences, University of Milan, Italy.
Stefanini
P
P
Medini
L
L
Tremoli
E
E
Colombo
C
C
Galli
C
C
D000001:Calcimycin / Q000494:pharmacology; D006801:Humans; D007375:Interleukin-1 / Q000494:pharmacology*; D009000:Monocytes / Q000187:drug effects / Q000201:enzymology*; D010713:Phosphatidylcholines / Q000378:metabolism*; D010716:Phosphatidylinositols / Q000378:metabolism*; D010738:Type C Phospholipases / Q000378:metabolism*
D007375:Interleukin-1; D010713:Phosphatidylcholines; D010716:Phosphatidylinositols; D000001:Calcimycin; D010738:Type C Phospholipases