Sensitization to the isothiazolinone biocide. Report of the Swiss Contact Dermatitis Research Group 1988-1990.
The rate of sensitization to isothiazolinones (Kathon CG) detected in Switzerland rose from 3.5% (out of 2,491 patients) in 1987 to 6.3% (out of 982 patients) in 1988 and 5.6% (out of 2,295 patients) in 1989-90. This rate of sensitization appears to be related to the more and more widespread use of isothiazolinone biocide in cosmetics, domestic products and in industry.
Hunziker
N
N
Clinique de Dermatologie, Hôpital cantonal, Genève, Switzerland.
Pasche
F
F
Bircher
A
A
Bruckner-Tuderman
L
L
Hunziker
T
T
Schmid
P
P
Suard
A
A
Suter
H
H
Perrenoud
D
D
Stäger
J
J
D003358:Cosmetics / Q000009:adverse effects; D003877:Dermatitis, Contact / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D010328:Patch Tests; D011310:Preservatives, Pharmaceutical / Q000009:adverse effects*; D015995:Prevalence; D013557:Switzerland / Q000453:epidemiology; D013844:Thiazoles / Q000009:adverse effects*
D003358:Cosmetics; D011310:Preservatives, Pharmaceutical; D013844:Thiazoles; C037057:Kathon 886