title: Role of perforin in lymphocyte-mediated cytolysis.
authors.affiliation: Department of Immunology, Juntendo University School of Medicine, Tokyo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Yagita
authors.forename: M
authors.initials: M
authors.lastname: Nakata
authors.forename: A
authors.initials: A
authors.lastname: Kawasaki
authors.forename: Y
authors.initials: Y
authors.lastname: Shinkai
authors.forename: K
authors.initials: K
authors.lastname: Okumura
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D002460:Cell Line; D002463:Cell Membrane Permeability; D003594:Cytoplasmic Granules / Q000378:metabolism; D003602:Cytotoxicity, Immunologic; D005089:Exocytosis; D005786:Gene Expression Regulation; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology* / Q000378:metabolism; D008407:Mast Cells / Q000276:immunology; D008562:Membrane Glycoproteins; D008563:Membrane Lipids / Q000378:metabolism; D008565:Membrane Proteins / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology*; D051379:Mice; D008954:Models, Biological; D008969:Molecular Sequence Data; D054353:Perforin; D052899:Pore Forming Cytotoxic Proteins; D011487:Protein Conformation; D011993:Recombinant Fusion Proteins / Q000502:physiology; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology* / Q000378:metabolism
chemical_list: D008562:Membrane Glycoproteins; D008563:Membrane Lipids; D008565:Membrane Proteins; D052899:Pore Forming Cytotoxic Proteins; D011993:Recombinant Fusion Proteins; D054353:Perforin