title: [Quantitatively evaluated dynamic magnetic resonance tomography in chronic polyarthritis of the knee joint. A therapeutic follow-up after intra-articular cortisone application].
abstract: 32 patients with chronic polyarthritis were examined by MRT. Following intra-articular application of 25 mg prednisolone, 18 patients were re-examined after two of three weeks and 7 out of 18 patients were re-examined after 8 to 16 weeks, both by MRT and clinically. After an initial double echo sequence, we carried out a dynamic series of FLASH measurements (TR 30, TE 10 ms, 70 degrees) following an intravenous bolus of 0.1 mmol gadolinium-DTPA. Single intensity-time curves were treated quantitatively in relation to the pannus, muscles and effusions. Two or three weeks after treatment the curve parameters showed a reduction in pannus vascularisation which remained constant for the 8 to 16 weeks of further observation. Contrast diffusion in the pannus is initially reduced but approaches the early measurements at the time of the second examination.
authors.affiliation: Abteilung für Radiologische Diagnostik und Nuklearmedizin, Klinikum Steglitz der FU.
authors.forename: H
authors.initials: H
authors.lastname: König
authors.forename: X
authors.initials: X
authors.lastname: Bolze
authors.forename: J
authors.initials: J
authors.lastname: Sieper
authors.forename: K J
authors.initials: KJ
authors.lastname: Wolf
mesh_terms: D000328:Adult; D000368:Aged; D001168:Arthritis / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D002908:Chronic Disease; D003348:Cortisone / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007270:Injections, Intra-Articular; D007719:Knee Joint / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D013585:Synovitis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology
chemical_list: D003348:Cortisone
vernacular_title: Quantitativ evaluierte dynamische Magnetresonanztomographie bei chronischer Polyarthritis des Kniegelenkes. Therapiekontrolle nach intraartikulärer Kortisonapplikation.