The antiproliferative effect of suramin on the cancer cell line SW-13 is mediated by the inhibition of transforming growth factor beta 1 (TGF-beta 1).
Danesi
R
R
Istituto di Farmacologia, Facoltà di Medicina e Chirurgia, Università degli Studi di Pisa.
Agen
C
C
Bernardini
N
N
Costa
M
M
Del Tacca
M
M
D000310:Adrenal Gland Neoplasms / Q000235:genetics / Q000473:pathology*; D015152:Blotting, Northern; D002455:Cell Division / Q000187:drug effects*; D015870:Gene Expression / Q000187:drug effects; D006801:Humans; D012333:RNA, Messenger / Q000235:genetics* / Q000378:metabolism; D012334:RNA, Neoplasm / Q000235:genetics / Q000378:metabolism; D013498:Suramin / Q000494:pharmacology*; D016212:Transforming Growth Factor beta / Q000235:genetics*; D014407:Tumor Cells, Cultured; D014410:Tumor Stem Cell Assay
D012333:RNA, Messenger; D012334:RNA, Neoplasm; D016212:Transforming Growth Factor beta; D013498:Suramin