title: Assignment of the porcine tumour necrosis factor alpha and beta genes to the chromosome region 7p11-q11 by in situ hybridization.
abstract: The loci of the porcine tumour necrosis factor genes, alpha (TNFA) and beta (TNFB), have been chromosomally assigned by radioactive in situ hybridization. The genomic probes for TNFA and TNFB yielded signals above 7p11-q11, a region that has been shown earlier to carry the porcine major histocompatibility locus (SLA). These mapping data along with preliminary molecular studies suggest a genomic organization of the SLA that is similar to that of human and murine major histocompatibility complexes.
authors.affiliation: Institut für Nutztierwissenschaften, Gruppe Züchtungsbiologie, Zürich, Switzerland.
authors.forename: S
authors.initials: S
authors.lastname: Solinas
authors.forename: U
authors.initials: U
authors.lastname: Pauli
authors.forename: P
authors.initials: P
authors.lastname: Kuhnert
authors.forename: E
authors.initials: E
authors.lastname: Peterhans
authors.forename: R
authors.initials: R
authors.lastname: Fries
mesh_terms: D000818:Animals; D002874:Chromosome Mapping / Q000379:methods*; D006801:Humans; D008285:Major Histocompatibility Complex / Q000235:genetics; D008297:Male; D009693:Nucleic Acid Hybridization; D013552:Swine / Q000235:genetics*; D014409:Tumor Necrosis Factor-alpha / Q000235:genetics*
chemical_list: D014409:Tumor Necrosis Factor-alpha