title: T1 squamous cell carcinoma of the arytenoid.
abstract: Twenty-two cases of early squamous cell carcinoma of the arytenoid cartilage staged as T1 according to the 1983 American Joint Committee for Cancer Staging Classification system were reviewed. Eighteen percent of the patients showed no symptoms. In the remaining 82%, the main presenting symptom was pain in the form of sore throat, odynophagia, or otalgia. Radiotherapy and partial laryngeal surgery were the options retained for the treatment of the larynx. A "watch and wait" policy or preventive treatment of the ipsilateral jugulocarotid lymph nodes were the treatment options retained for the neck. Significant differences were noted in terms of local and nodal recurrence between the two programs. Results indicate that partial laryngeal surgery with total arytenoidectomy and preventive treatment of the neck appear to be advisable for this particular type of primary lesion.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, Hôpital Laënnec, University of Paris V, France.
authors.forename: O
authors.initials: O
authors.lastname: Laccourreye
authors.forename: G
authors.initials: G
authors.lastname: Weinstein
authors.forename: E
authors.initials: E
authors.lastname: Chabardes
authors.forename: M
authors.initials: M
authors.lastname: Housset
authors.forename: H
authors.initials: H
authors.lastname: Laccourreye
authors.forename: D
authors.initials: D
authors.lastname: Brasnu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001193:Arytenoid Cartilage / Q000473:pathology* / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000556:secondary / Q000601:surgery / Q000628:therapy*; D002945:Cisplatin / Q000008:administration & dosage; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000517:prevention & control / Q000532:radiotherapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D007825:Laryngectomy; D008207:Lymphatic Metastasis / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy; D015996:Survival Rate; D016896:Treatment Outcome; D014805:Vitamin B 12 / Q000627:therapeutic use
chemical_list: D003037:Cobalt Radioisotopes; D014805:Vitamin B 12; D002945:Cisplatin; D005472:Fluorouracil