[Allotransplantation of meniscus in dog's knee. An experimental study].
This experimental study was to show the difference and outcome of allotransplantation and autotransplantation of meniscus in dogs. In the experimental group (9 dogs), the lateral meniscus was removed and replaced by one preserved for 2 weeks in tissue culture. In the control group (9 dogs), the lateral meniscus was excised but was sutured back to the place immediately. The specimens in each group were taken at 3, 6, 12, and 24 weeks after operation, and were examined microangiographically and histologically under light microscope and electron microscope. The results in both groups showed that the meniscus united to the capsule, chondrocytes in the menisci were intact and the collagen fiber orientation was regular. The articular cartilage of the uncovered area of the tibial plateaus showed normal appearance, and vascular neogenesis in the meniscal periphery was found 12 weeks after operation. These observations suggest that allogenic meniscus maintains its original histologic pattern and functional behavior after its transplantation. It makes possible to protect the knee joint from osteoarthritis.
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Beijing Institute of Traumatology and Orthopaedics.
D000818:Animals; D002358:Cartilage, Articular / Q000166:cytology; D004285:Dogs; D006614:Hindlimb; D007596:Joints / Q000601:surgery; D008592:Menisci, Tibial / Q000637:transplantation*; D009926:Organ Preservation; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous; D016896:Treatment Outcome