title: Progressive soft tissue uptake of Tc-99m MDP reflecting metastatic microcalcification.
abstract: A 49-year-old woman had longstanding renal impairment. Markedly increased uptake of Tc-99m MDP in the heart, lungs, and kidneys was an incidental finding on bone scintigraphy performed to exclude metastatic bone disease. These findings persisted on repeat bone imaging 1 year later. In addition, gastric and skeletal muscle uptake was subsequently seen. Soft tissue microcalcification was confirmed by computed tomography and renal biopsy. A consideration of the differential diagnosis is presented.
authors.affiliation: Department of Nuclear Medicine, Repatriation General Hospital, Heidelberg, Victoria, Australia.
authors.forename: R D
authors.initials: RD
authors.lastname: Low
authors.forename: R J
authors.initials: RJ
authors.lastname: Hicks
authors.forename: L B
authors.initials: LB
authors.lastname: Arkles
authors.forename: G
authors.initials: G
authors.lastname: Gill
authors.forename: W
authors.initials: W
authors.lastname: Adam
mesh_terms: D001859:Bone Neoplasms / Q000000981:diagnostic imaging*; D002114:Calcinosis / Q000000981:diagnostic imaging* / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007668:Kidney / Q000378:metabolism*; D008168:Lung / Q000378:metabolism*; D008875:Middle Aged; D009206:Myocardium / Q000378:metabolism*; D011877:Radionuclide Imaging; D013669:Technetium Tc 99m Medronate / Q000493:pharmacokinetics*
chemical_list: D013669:Technetium Tc 99m Medronate