Alterations in the hematological profile in rat following whole body gamma radiation with and without venoruton pretreatment.
The radioprotective effect of venoruton [O-(beta-hydroxyethyl)-rutoside] has been assessed in the hematological profile of Swiss albino male rats subjected to a single dose of 300 rads whole body gamma radiation. The results showed that the severity of the radiation-induced abnormalities in the red and white blood cells is significantly lessened by venoruton administered prior to radiation exposure.
Kanwar
K C
KC
Department of Biophysics, Panjab University, Chandigarh, India.
Verma
A
A
D000818:Animals; D004906:Erythrocyte Count; D016166:Free Radical Scavengers; D006400:Hematocrit; D006403:Hematologic Tests; D006896:Hydroxyethylrutoside / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D007958:Leukocyte Count; D008297:Male; D011837:Radiation-Protective Agents / Q000494:pharmacology*; D051381:Rats; D014916:Whole-Body Irradiation
D016166:Free Radical Scavengers; D006896:Hydroxyethylrutoside; D011837:Radiation-Protective Agents; C005865:troxerutin