title: Periodic alternating gaze deviation in infancy.
abstract: Periodic alternating gaze is a rarely reported phenomenon. We have observed two cases that are unique in their early onset at birth and infancy. Multiple congenital defects of the posterior cranial fossa were present on MRI in both cases. A prominent abnormality shared by both was absence of normal structures in the region of the inferior cerebellar vermis. Periodic alternating gaze appears to be associated with pathologic changes in the hindbrain in these and other reported cases.
authors.affiliation: Department of Ophthalmology, New England Medical Center, Tufts University, Boston, MA.
authors.forename: R H
authors.initials: RH
authors.lastname: Legge
authors.forename: H S
authors.initials: HS
authors.lastname: Weiss
authors.forename: T R
authors.initials: TR
authors.lastname: Hedges
authors.forename: M L
authors.initials: ML
authors.lastname: Anderson
mesh_terms: D001921:Brain / Q000002:abnormalities* / Q000503:physiopathology; D005133:Eye Movements / Q000502:physiology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D010507:Periodicity