title: Experiments on the effects of several factors on the 1-hydroxypyrene level in human urine as an indicator of exposure to polycyclic aromatic hydrocarbons.
abstract: The concentration of 1-hydroxypyrene in human urine was determined in six volunteers who lived under the same conditions. Samples were collected four times per day for three consecutive days; the maximum concentration of 1-hydroxypyrene was found in the samples collected late in the evening (21:00-23:00 h) which is the time recommended as suitable for determination of urinary 1-hydroxypyrene for the purpose of evaluating human exposure to polycyclic aromatic hydrocarbons (PAHs). Statistical tests show that the influence of sex, age, and smoking on urinary 1-hydroxypyrene is statistically insignificant.
authors.affiliation: Beijing Municipal Research Institute of Environmental Protection, China.
authors.forename: Z H
authors.initials: ZH
authors.lastname: Zhao
authors.forename: W Y
authors.initials: WY
authors.lastname: Quan
authors.forename: D H
authors.initials: DH
authors.lastname: Tian
mesh_terms: D000328:Adult; D000367:Age Factors; D015415:Biomarkers / Q000652:urine; D003404:Creatinine / Q000652:urine; D004781:Environmental Exposure; D004784:Environmental Monitoring / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D009153:Mutagens / Q000032:analysis*; D011083:Polycyclic Compounds; D011721:Pyrenes / Q000032:analysis*; D012621:Seasons; D012727:Sex Characteristics; D012907:Smoking / Q000652:urine
chemical_list: D015415:Biomarkers; D009153:Mutagens; D011083:Polycyclic Compounds; D011721:Pyrenes; D003404:Creatinine; C033146:1-hydroxypyrene