title: [Transcatheter radiofrequency modulation and ablation of the atrioventricular junction in supraventricular arrhythmias refractory to medical therapy].
abstract: In patients with supraventricular tachyarrhythmias refractory to medical therapy, transcatheter ablation (TA) is necessary. From January 1990, in 27 patients with nodal tachycardia and 6 with atrial fibrillation or flutter, referred to our institution for electrophysiologic evaluation, TA by radiofrequency (RF) was performed, respectively for atrioventricular (AV) junction modulation and total AV junction ablation. In all these cases, a total refractoriness to several antiarrhythmic drugs alone or in combination had been observed. The RF current, generated by the Osypka HAT 100 device, was administered through a tripolar USCI 7 F catheter. The ideal site for energy delivery was defined on the basis of a mapping, performed in the AV junction area to find out the most premature retrograde atrial activation. Local atrial activation time was evaluated during nodal tachycardia by delivering a premature ventricular extrastimulus to discover the atrial deflection from the ventricular one. In the selected area, 5 applications (range 1-12) of 20-25 W power RF energy for 5-30 s were delivered on average. A complete prevention of nodal tachycardia was achieved in 26/27 patients (96.2%). Only in 2 patients (7.4%) a total AV block was induced. The pre- and post-procedure values are as follows: AH = pre 71 +/- 18, post 113.2 +/- 53; HV = pre 46.4 +/- 8, post 48 +/- 7; anterograde Wenckebach point = pre 352 +/- 56, post 389 +/- 91; retrograde Wenckebach point = pre 338 +/- 75, post 419 +/- 61. In 13/27 cases the AH interval was normal after RF application. The retrograde conduction was worsened in all patients and totally abolished in 12/27.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Divisione di Cardiologia, IRCCS Policlinico S Matteo, Università degli Studi, Pavia.
authors.forename: C
authors.initials: C
authors.lastname: Storti
authors.forename: R
authors.initials: R
authors.lastname: De Ponti
authors.forename: M
authors.initials: M
authors.lastname: Zardini
authors.forename: F
authors.initials: F
authors.lastname: Cellino
authors.forename: M
authors.initials: M
authors.lastname: Longobardi
authors.forename: A
authors.initials: A
authors.lastname: Ferrari
authors.forename: E
authors.initials: E
authors.lastname: Massacci
authors.forename: J A
authors.initials: JA
authors.lastname: Salerno
mesh_terms: D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000503:physiopathology / Q000601:surgery*; D001283:Atrioventricular Node / Q000503:physiopathology / Q000601:surgery*; D002304:Cardiac Pacing, Artificial; D004564:Electrocoagulation / Q000295:instrumentation / Q000379:methods*; D004594:Electrophysiology; D005260:Female; D005471:Fluoroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D000078702:Radiofrequency Therapy; D015641:Radiography, Interventional
vernacular_title: Modulazione e ablazione transcatetere mediante radiofrequenza della giunzione atrioventricolare in aritmie sopraventricolari refrattarie alla terapia medica.