title: Severe laryngotracheobronchitis complicating measles.
abstract: OBJECTIVE
  To determine the incidence of severe measles-related laryngotracheobronchitis in patients hospitalized during a recent measles epidemic and to evaluate factors associated with severity of airway injury and its management.
  
  
  METHODS
  Clinical description of patient series.
  
  
  METHODS
  Children's hospital and county general hospital, Houston, Tex.
  
  
  METHODS
  One hundred twenty-four children (aged 1 month to 19 years) admitted with a diagnosis of measles.
  
  
  METHODS
  None.
  
  
  RESULTS
  Twenty-seven patients had significant laryngotracheobronchitis, including 10 who had not received appropriate immunization. Six patients required endotracheal intubation for relief of upper airway obstruction. The median age of patients requiring intubation was 12 months (range, 4 to 24 months). Two patients died of complications of superinfection. Two patients survived but required prolonged intubation. Two patients underwent early diagnostic laryngoscopy and bronchoscopy and required shorter artificial airway maintenance.
  
  
  CONCLUSIONS
  Severe laryngotracheobronchitis frequently occurs in patients younger than 2 years hospitalized with measles and may be related to bacterial or viral super-infection. Early diagnostic laryngoscopy and bronchoscopy for injury assessment and possible endotracheal tube exchange are recommended and, in some severe cases, tracheostomy should be considered to shorten artificial airway maintenance and decrease the incidence of airway complications.
authors.affiliation: Department of Pediatrics, Baylor College of Medicine, Houston, Tex.
authors.forename: J D
authors.initials: JD
authors.lastname: Fortenberry
authors.forename: M M
authors.initials: MM
authors.lastname: Mariscalco
authors.forename: P T
authors.initials: PT
authors.lastname: Louis
authors.forename: F
authors.initials: F
authors.lastname: Stein
authors.forename: J K
authors.initials: JK
authors.lastname: Jones
authors.forename: L S
authors.initials: LS
authors.lastname: Jefferson
mesh_terms: D000293:Adolescent; D001991:Bronchitis / Q000150:complications* / Q000628:therapy; D001999:Bronchoscopy; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007249:Inflammation; D007442:Intubation, Intratracheal; D007818:Laryngeal Diseases / Q000150:complications* / Q000628:therapy; D007828:Laryngoscopy; D008457:Measles / Q000150:complications*; D015163:Superinfection / Q000150:complications*; D014133:Tracheal Diseases / Q000150:complications* / Q000628:therapy