title: The need for toothpastes with lower than conventional fluoride concentrations for preschool-aged children.
abstract: Since 1945, when community water fluoridation was first implemented in the United States, not only has the procedure grown to cover more than half of the US population, but the development and use of other fluoride methods have expanded greatly. A concomitant, dramatic decrease has occurred in the caries prevalence of US school-aged children. Recent studies indicate, however, that the prevalence and, to a lesser extent, the intensity of dental fluorosis have increased in schoolchildren in both fluoridated and fluoride-deficient areas. Several studies show that young children inadvertently ingest sizable proportions of toothpaste during toothbrushing. Although ingestion of fluoride toothpastes by preschool-aged children may not be the major contributor to the increase in fluorosis, the findings of at least four studies suggest that the use of fluoride toothpastes by young children is a risk factor. The direct dose-response relation between effectiveness and fluoride concentration of toothpastes is far from clear-cut and, at best, is weak. Thus, considering today's reduced risk of caries, it is timely to market fluoride toothpastes in the US with 400-500 ppm fluoride for preschool-aged children, who are still at risk for developing fluorosis, as has been done in several other countries. Dental public health authorities must work with toothpaste manufacturers, professional organizations, and regulatory agencies to facilitate the approval and marketing of such pediatric fluoride toothpastes.
authors.affiliation: Dental Research and Public Health, Bethesda, MD 20817.
authors.forename: H S
authors.initials: HS
authors.lastname: Horowitz
mesh_terms: D002675:Child, Preschool; D003731:Dental Caries / Q000517:prevention & control; D005459:Fluorides / Q000008:administration & dosage / Q000032:analysis*; D009050:Fluorosis, Dental / Q000517:prevention & control; D006801:Humans; D012307:Risk Factors; D014100:Toothpastes / Q000032:analysis*
chemical_list: D014100:Toothpastes; D005459:Fluorides