title: Telogen effluvium due to recombinant interferon alpha-2b.
abstract: Five of 10 patients receiving long-term recombinant interferon alpha-2b therapy complained of considerable hair loss. The pull test and the trichogram showed a telogen count consistent with a telogen effluvium. In 2 patients the telogen count progressively improved despite continuing the treatment, whereas in 3 patients the trichogram continued to show an increased telogen count until interferon therapy was discontinued. Pohl-Pinkus hair constrictions were also present in 2 patients.
authors.affiliation: Department of Dermatology, University of Bologna, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Tosti
authors.forename: C
authors.initials: C
authors.lastname: Misciali
authors.forename: F
authors.initials: F
authors.lastname: Bardazzi
authors.forename: P A
authors.initials: PA
authors.lastname: Fanti
authors.forename: C
authors.initials: C
authors.lastname: Varotti
mesh_terms: D000328:Adult; D000368:Aged; D000505:Alopecia / Q000139:chemically induced*; D005260:Female; D006197:Hair / Q000187:drug effects* / Q000254:growth & development; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000009:adverse effects / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D011994:Recombinant Proteins
chemical_list: D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins