title: [Clinical evaluation of meropenem in children].
abstract: Meropenem (MEPM) was evaluated for its efficacy and safety. The following results were obtained. MEPM was given to 12 patients with infections: 5 with pneumonia, 1 with bacterial meningitis, 2 with pharyngitis, 4 with skin and soft tissue infections. Therapeutic responses were "excellent" in 5, "good" in 4 and "fair" in 3, with an efficacy rate of 75%. Adverse reactions were not noted. No abnormalities were shown in laboratory data. It has been concluded that MEPM is a useful drug for the treatment of bacterial infections in children.
authors.affiliation: Department of Pediatrics, Sapporo City General Hospital.
authors.forename: N
authors.initials: N
authors.lastname: Fukushima
authors.forename: A
authors.initials: A
authors.lastname: Ishikawa
authors.forename: A
authors.initials: A
authors.lastname: Takase
authors.forename: Y
authors.initials: Y
authors.lastname: Wagatsuma
mesh_terms: D000293:Adolescent; D000328:Adult; D000421:Alcaligenes / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006192:Haemophilus Infections / Q000188:drug therapy; D006193:Haemophilus influenzae; D006801:Humans; D007223:Infant; D008297:Male; D011552:Pseudomonas Infections / Q000188:drug therapy; D013203:Staphylococcal Infections / Q000188:drug therapy; D014974:Xanthomonas / Q000187:drug effects