Chorionic villus sampling in Auckland 1989-90.
OBJECTIVE
to perform an audit of all 197 chorionic villus sampling procedures performed in Auckland in 1989-90.


METHODS
an attempt to trace the outcome in all 197 cases and this was possible in 188 cases.


RESULTS
89% of chorionic villus samples were performed transvaginally and 11% transabdominally. The total fetal loss rate was 9.6% (18) with six spontaneous miscarriages before 20 weeks gestation (3.2%), one intermediate fetal death and one neonatal death. There were 10 elective terminations of pregnancy following abnormal results so the spontaneous loss rate was 4.3%.


CONCLUSIONS
the loss rate was lower than that reported in the European and Canadian multicentre trials. The sampling success rate, however, was poor with 13.7% failed procedures. This improved in the second year of the service to 10%. There were no failure cultures or examples of mosaicism.
Birdsall
M
M
Department of Obstetrics, Auckland University School of Medicine, National Women's Hospital.
Roberts
A B
AB
Fisher
R
R
Beecroft
D
D
Bailey
R
R
D000022:Abortion, Spontaneous / Q000453:epidemiology / Q000209:etiology; D000032:Abortion, Therapeutic / Q000706:statistics & numerical data; D000328:Adult; D000649:Amniocentesis / Q000706:statistics & numerical data; D015193:Chorionic Villi Sampling / Q000009:adverse effects / Q000592:standards / Q000706:statistics & numerical data*; D005260:Female; D005313:Fetal Death / Q000453:epidemiology / Q000209:etiology; D005500:Follow-Up Studies; D006771:Hospitals, Maternity; D006779:Hospitals, Public; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D008423:Maternal Age; D008485:Medical Audit; D008487:Medical History Taking; D009520:New Zealand / Q000453:epidemiology; D011247:Pregnancy; D011256:Pregnancy Outcome