title: [The piezoelectric lithotripsy of gallstones. The acute- and long-term results].
abstract: Extracorporeal piezoelectric lithotripsy (PEL) with oral lysis (about 7.5 mg/kg urso- and chenodeoxycholic acid as single dose in the evening) was performed, according to a standardized treatment and follow-up protocol, in 219 patients (177 women, 42 men; aged 47 +/- 14 years) with symptoms of gallbladder stones. The average number of treatment sessions per patient was 2.0 +/- 0.8. Significantly fewer sessions with fewer shockwave charges were required in solitary gallstones of less than or equal to 20 mm diameter than in those of greater than 20 mm diameter and in multiple concrements (P less than 0.01). Fragmentation was successful in 99% of patients. Sedation and/or analgesia during PEL were required in only 2% of patients. There were no marked side effects during the treatment. The stone-free rate 12 months after the start of treatment was 76% in the group with solitary stones less than or equal to 20 mm, 75% with solitary stones greater than 20 mm and 64% for multiple stones. During the follow-up period 36% of patients had biliary colics and 3% had fragments impacted in the common bile duct. Biliary pancreatitis occurred in 1% of patients. PEL is an effective and sparing procedure in the treatment of selected patients with gallbladder stones.
authors.affiliation: Medizinische Klinik I, Universität Erlangen-Nürnberg.
authors.forename: J
authors.initials: J
authors.lastname: Benninger
authors.forename: H T
authors.initials: HT
authors.lastname: Schneider
authors.forename: M
authors.initials: M
authors.lastname: Blaufuss
authors.forename: T
authors.initials: T
authors.lastname: Rabenstein
authors.forename: H
authors.initials: H
authors.lastname: Flügel
authors.forename: E G
authors.initials: EG
authors.lastname: Hahn
authors.forename: C
authors.initials: C
authors.lastname: Ell
mesh_terms: D000328:Adult; D000368:Aged; D001659:Biliary Tract / Q000000981:diagnostic imaging; D002635:Chenodeoxycholic Acid / Q000008:administration & dosage; D016009:Chi-Square Distribution; D002769:Cholelithiasis / Q000453:epidemiology / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D005704:Gallbladder / Q000000981:diagnostic imaging; D006801:Humans; D008096:Lithotripsy / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013997:Time Factors; D014463:Ultrasonography; D014580:Ursodeoxycholic Acid / Q000008:administration & dosage
chemical_list: D002635:Chenodeoxycholic Acid; D014580:Ursodeoxycholic Acid
vernacular_title: Piezoelektrische Lithotripsie von Gallenblasensteinen. Akut- und Langzeitergebnisse.