[Trials of the diagnostic potentials of TPA in tumorous and nontumorous lung pathologies in 303 cases].
Serum tissue polypeptide antigen (TPA) has been determined in 271 patients with pleural or pulmonary neoplastic diseases (131) or with benign lung diseases (140). Using a cut-off of 95 U/L, TPA has a sensitivity and specificity of 65%. Therefore, TPA serum determination can suggest a diagnosis of malignancy, but its evaluation, as a single test, is not useful to differentiate between malignant or benign disease. TPA can be useful as an ancillary test in the follow-up of lung cancer therapy.
Aquilina
R
R
Divisione Pneumologica, Ospedale G. F. Novaro, Costarainera, IM.
Bergero
F
F
Magri
G
G
Noceti
P
P
Mirabelli
S
S
D000951:Antigens, Neoplasm / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood*; D003937:Diagnosis, Differential; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis*; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000556:secondary; D008297:Male; D010455:Peptides / Q000097:blood*; D010995:Pleural Diseases / Q000175:diagnosis; D010997:Pleural Neoplasms / Q000175:diagnosis / Q000556:secondary; D012680:Sensitivity and Specificity; D019396:Tissue Polypeptide Antigen
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D010455:Peptides; D019396:Tissue Polypeptide Antigen
Sperimentazioni sulla potenzialità diagnostica del TPA nelle patologie tumorali e non del polmone in 303 casi.