Reduced levels of free testosterone in four Catania-type alloalbuminemic males.
We studied total testosterone, sex hormone binding globulin, and free testosterone in four males presenting an electrophoretically slow-moving genetic variant of albumin, the alloalbumin Catania. Free testosterone levels were lower in these cases, found in a year of observation, than those expected for the ages. This finding, which is not related to any disease and constantly not recognized in other males with various genetic variants, should induce consideration of a probable difference of the genetic variant in hormone binding.
Banfi
G
G
Laboratorio Analisi, Istituto Scientifico H San Raffaele, Milano, Italy.
Daverio
R
R
Bonini
P
P
D000293:Adolescent; D000328:Adult; D000595:Amino Acid Sequence; D014644:Genetic Variation; D006801:Humans; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D009154:Mutation; D012709:Serum Albumin / Q000235:genetics* / Q000378:metabolism; D012738:Sex Hormone-Binding Globulin / Q000378:metabolism; D013739:Testosterone / Q000097:blood*
D012709:Serum Albumin; D012738:Sex Hormone-Binding Globulin; D013739:Testosterone