title: Intraocular penetration of rifampin in humans.
abstract: The penetration of rifampin into human aqueous humor was determined in 15 patients undergoing elective cataract surgery. Between 0.9 and 5.5 h after administration of a single 600-mg oral dose, concentrations ranged from 6.0 to 21.5 mg/liter in serum and from less than 0.2 to 1.3 mg/liter in aqueous humor.
authors.affiliation: Department of Pharmacy Services, Hartford Hospital, Connecticut 06115.
authors.forename: W R
authors.initials: WR
authors.lastname: Outman
authors.forename: R E
authors.initials: RE
authors.lastname: Levitz
authors.forename: D A
authors.initials: DA
authors.lastname: Hill
authors.forename: C H
authors.initials: CH
authors.lastname: Nightingale
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000369:Aged, 80 and over; D001082:Aqueous Humor / Q000737:chemistry*; D002387:Cataract Extraction; D006801:Humans; D012293:Rifampin / Q000097:blood / Q000737:chemistry*
chemical_list: D012293:Rifampin