Peroperative arterial hypoxaemia. The interaction between intrapulmonary shunt and cardiac output. A computer model.
A computer model of respiratory physiology was used to investigate the interaction between cardiac output and intrapulmonary shunting during anaesthesia. Significant degrees of arterial desaturation were demonstrated as the cardiac output was reduced. We suggest that volume expansion may correct some episodes of desaturation observed during anaesthesia.
Westbrook
J L
JL
Nuffield Department of Anaesthetics, Radcliffe Infirmary, Oxford.
Sykes
M K
MK
D002302:Cardiac Output; D003198:Computer Simulation; D006801:Humans; D000860:Hypoxia / Q000209:etiology*; D007431:Intraoperative Complications / Q000209:etiology*; D008168:Lung / Q000502:physiology; D008954:Models, Biological; D011175:Positive-Pressure Respiration; D012119:Respiration / Q000502:physiology*