title: [Mannitol solution (M-400) vs. mannitol solution combined with allopurinol in the prevention of post-transfusion acute renal failure].
abstract: Evaluation on the incidence of Acute Renal Failure (ARF) from a total of 41 corpse renal graft receptors, 20 of which received perfusion with mannitol solution at 400 mOsm/kg (Group 1) and 21 the same mannitol solution plus allopurinol (Group 2). No significant differences were present between both groups when they were analyzed for ARF incidence (15% vs 23.8%); overall incidence was 19.5%. 24-hour initial diuresis was shown to be an excellent predictor for long-term graft functionality. We can conclude that the addition of mannitol to the perfusion solution contributes decisively to reduce post-transplantation ARF, while addition of allopurinol does not have further beneficial effects.
authors.affiliation: Servicio de Urología, Hospital Príncipes de España, L'Hospitalet, Barcelona.
authors.forename: M A
authors.initials: MA
authors.lastname: López-Costea
authors.forename: J M
authors.initials: JM
authors.lastname: Griñó
authors.forename: D
authors.initials: D
authors.lastname: Serón
authors.forename: R
authors.initials: R
authors.lastname: Domingo
authors.forename: J M
authors.initials: JM
authors.lastname: Caballero
authors.forename: L
authors.initials: L
authors.lastname: Riera
authors.forename: E
authors.initials: E
authors.lastname: Franco-Miranda
authors.forename: N
authors.initials: N
authors.lastname: Serrallach
mesh_terms: D058186:Acute Kidney Injury / Q000517:prevention & control*; D000493:Allopurinol / Q000008:administration & dosage*; D002102:Cadaver; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D006084:Graft Rejection / Q000187:drug effects; D006801:Humans; D016030:Kidney Transplantation; D008353:Mannitol / Q000008:administration & dosage*
chemical_list: D008353:Mannitol; D000493:Allopurinol
vernacular_title: Solución de manitol (M-400) versus solución de manitol y alopurinol en la prevención del fracaso renal agudo post-TR.