title: Cross-sectional early mitral flow-velocity profiles from color Doppler in patients with mitral valve disease.
abstract: BACKGROUND
  Cross-sectional flow-velocity profiles from early mitral flow in 20 patients (10 with mitral regurgitation and 10 with mitral stenosis) were constructed from the velocity data from each point in sequentially delayed two-dimensional digital Doppler ultrasound maps.
  
  
  RESULTS
  The data suggested that the early mitral flow studied in an apical four-chamber view was variably skewed in both patient groups. The maximum flow velocity overestimated the cross-sectional mean velocity at the same time by a factor of 1.12-1.86. The maximum time-velocity integral was 1.13-1.77-fold greater than the cross-sectional mean time-velocity integral. In patients with mitral regurgitation, the cross-sectional flow-velocity profile appeared to be most skewed at the level of the mitral leaflet tips. The level of the mitral annulus appeared to give the most homogenous flow-velocity distribution in both patient groups.
  
  
  CONCLUSIONS
  When calculations of volume flow are based on pulsed Doppler ultrasound recordings with a single sample volume, the possibility of a skewed flow-velocity profile must be taken into account.
authors.affiliation: Section of Cardiology, Regional Hospital of Trondheim, Norway.
authors.forename: S O
authors.initials: SO
authors.lastname: Samstad
authors.forename: O
authors.initials: O
authors.lastname: Rossvoll
authors.forename: H G
authors.initials: HG
authors.lastname: Torp
authors.forename: T
authors.initials: T
authors.lastname: Skjaerpe
authors.forename: L
authors.initials: L
authors.lastname: Hatle
mesh_terms: D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D003430:Cross-Sectional Studies; D015150:Echocardiography, Doppler; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging* / Q000503:physiopathology; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging* / Q000503:physiopathology; D008946:Mitral Valve Stenosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D012039:Regional Blood Flow; D013997:Time Factors