title: Dermal angiosarcoma of the breast: a complication of primary radiotherapy?
abstract: A 70-year-old female developed recurrent disease following radiotherapy for primary inoperable breast cancer 5.5 years previously. Salvage mastectomy was performed. Pathology revealed recurrent breast cancer, along with a second primary malignancy, a dermal angiosarcoma. Radical excision of recurrent angiosarcoma failed. Irradiation combined with hyperthermia showed good palliation. The angiosarcoma's possible relation to the initial radiotherapy is discussed.
authors.affiliation: Department of Surgery, Academic Medical Centre, University of Amsterdam, The Netherlands.
authors.forename: C W
authors.initials: CW
authors.lastname: Taat
authors.forename: B S
authors.initials: BS
authors.lastname: van Toor
authors.forename: J F
authors.initials: JF
authors.lastname: Slors
authors.forename: J
authors.initials: J
authors.lastname: Bras
authors.forename: L E
authors.initials: LE
authors.lastname: Blank
authors.forename: F
authors.initials: F
authors.lastname: van Coevorden
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D006394:Hemangiosarcoma / Q000209:etiology* / Q000473:pathology; D006801:Humans; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D016609:Neoplasms, Second Primary / Q000209:etiology* / Q000473:pathology; D011878:Radiotherapy / Q000009:adverse effects; D012878:Skin Neoplasms / Q000209:etiology* / Q000473:pathology