Chromosome mapping of the owl monkey CSF1R and IL5 genes.
We mapped the owl monkey colony-stimulating factor 1 receptor (CSF1R) locus to the proximal region of chromosome 3q of karyotype VI(K-VI) and karyotype V(K-V) and the interleukin 5 (IL5) locus to the mid-region of chromosome 3q(K-VI) and 19q(K-IV) using a combination of Southern hybridization of somatic cells and in situ chromosomal hybridization methodologies. The findings support the proposed evolution of owl monkey chromosome 3(K-VI) from a fusion of two smaller structures, the homologs of chromosomes 6 and 19 (K-IV). The data also indicate genomic conservation of the HSA 5q23-q35 segment in the higher primates.
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Department of Pathology, New England Regional Primate Research Center, Southborough, Massachusetts 01772-9102.
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D000818:Animals; D016645:Aotidae / Q000235:genetics*; D015139:Blotting, Southern; D002874:Chromosome Mapping; D004247:DNA; D015342:DNA Probes; D006822:Hybrid Cells; D015848:Interleukin-5 / Q000235:genetics*; D007621:Karyotyping; D016173:Macrophage Colony-Stimulating Factor / Q000235:genetics*; D012377:Rodentia
D015342:DNA Probes; D015848:Interleukin-5; D016173:Macrophage Colony-Stimulating Factor; D004247:DNA