An hypothesis for a contractile protein based on the principles of submicroscopic physiology.
The discovery of the polyguanidinium ring complex and its various properties has emphasised the versatility of arginines in functional proteins. In an extension of these studies the possibility of formulating a polypeptide which could be the basis for a contractile element in muscle presented itself. Although hypothetical, the deduced molecular properties, based on the unique chemistry of arginine guanido groups are in keeping with known functional aspects of some muscles, and could form the foundation for a more detailed theory of muscular contraction. The structural requirements and the theoretical principles involved are briefly described in this paper.
Widdas
W F
WF
Department of Biology (Physiology), Royal Holloway and Bedford New College, Egham, Surrey, Great Britain.
Baker
G F
GF
D008958:Models, Molecular; D009124:Muscle Proteins / Q000737:chemistry* / Q000502:physiology*
D009124:Muscle Proteins