Paraneoplastic myelopathy at diagnosis in a patient with pathologic stage 1A Hodgkin disease.
The case of a patient with pathologic Stage 1A Hodgkin disease is reported in whom subacute paraneoplastic myelopathy developed before treatment. Myelography, computed tomography, magnetic resonance imaging, and lumbar puncture examination showed no evidence of central nervous system involvement. The patient was treated with combination chemotherapy (to avoid spinal cord exposure to radiation) without neurologic improvement. The patient's neurologic condition responded well to intrathecal dexamethasone.
Hughes
M
M
Department of Medical Oncology, Westmead Hospital, New South Wales, Australia.
Ahern
V
V
Kefford
R
R
Boyages
J
J
D003907:Dexamethasone / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006689:Hodgkin Disease / Q000150:complications* / Q000473:pathology; D006801:Humans; D007278:Injections, Spinal; D008875:Middle Aged; D009188:Myelitis, Transverse / Q000188:drug therapy / Q000209:etiology*; D010257:Paraneoplastic Syndromes / Q000188:drug therapy; D010264:Paraplegia / Q000188:drug therapy / Q000209:etiology*
D003907:Dexamethasone