[Hermaphroditism and male pseudohermaphroditism].
In the human embryo, sex is all in the genes. Later on, the male and female sexual characters, which are products of the expression of all individual genomes, differentiate men from women. In this paper, the embryogenesis and morphology of true hermaphroditism and male pseudo-hermaphroditism are studied. These are intersexual states determined by errors in genital programme transmission. A relationship is established between the biochemical identification of substances secreted by the testis and the evolution of sexual characters. The genesis of sexual abnormalities according to the stage when the testicular deficit appears is envisaged. The clinical, anatomical, histological and biochemical aspects of these intersexual states are described.
Minh
H N
HN
Service central d'Anatomie et de Cytologie pathologiques, Hôpital Nord, CHRU, Amiens.
Belaisch
J
J
Smadja
A
A
D015096:3-Hydroxysteroid Dehydrogenases / Q000172:deficiency; D013741:3-Oxo-5-alpha-Steroid 4-Dehydrogenase / Q000172:deficiency; D013734:Androgen-Insensitivity Syndrome / Q000235:genetics / Q000503:physiopathology; D012734:Disorders of Sex Development / Q000235:genetics / Q000503:physiopathology*; D005260:Female; D006061:Gonadal Dysgenesis, 46,XY / Q000503:physiopathology; D006801:Humans; D007713:Klinefelter Syndrome / Q000235:genetics / Q000503:physiopathology; D008297:Male
D015096:3-Hydroxysteroid Dehydrogenases; D013741:3-Oxo-5-alpha-Steroid 4-Dehydrogenase
Hermaphrodisme et pseudo-hermaphrodisme masculin.