Hepatotoxicity with the administration of nifedipine for treatment of preterm labor.
Nifedipine, a calcium channel blocker, is becoming increasingly popular as a tocolytic medication. Previous reports of hepatitis associated with nifedipine in the medical literature have been published. We present the first case reported of a patient with preterm labor treated with nifedipine who had development of a concurrent elevation in serum liver enzyme levels.
Sawaya
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GF
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco Medical Center 94143-0346.
Robertson
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PA
D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D005260:Female; D006801:Humans; D007260:Infusion Pumps; D008099:Liver / Q000187:drug effects*; D008278:Magnesium Sulfate / Q000627:therapeutic use; D009543:Nifedipine / Q000009:adverse effects* / Q000627:therapeutic use; D007752:Obstetric Labor, Premature / Q000188:drug therapy*; D011247:Pregnancy; D013726:Terbutaline / Q000627:therapeutic use
D008278:Magnesium Sulfate; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D009543:Nifedipine; D013726:Terbutaline