Comparison of results obtained with human serum and a protein solution as a supplement for in vitro fertilization culture medium.
A prospective controlled study was performed to compare the PRs obtained after use of a uniform IVF culture medium containing a pasteurized serum protein solution or patient serum. The ongoing PRs per ET in the serum and the protein solution group were 32% and 28%, respectively (not significant). Culture of supernumerary embryos showed blastocyst formation and even hatching with both supplements. The PR will not drop when this protein solution is used as a protein supplement in IVF culture medium instead of patient serum.
Huisman
G J
GJ
Department of Obstetrics and Gynaecology, Academic Hospital Rotterdam Dijkzigt, The Netherlands.
Lo-A-Njoe
N M
NM
Alberda
A T
AT
Leerentveld
R A
RA
Verhoeff
A
A
Zeilmaker
G H
GH
D001769:Blood; D001798:Blood Proteins; D003470:Culture Media; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D011446:Prospective Studies; D012996:Solutions
D001798:Blood Proteins; D003470:Culture Media; D012996:Solutions