Polymers having (1----4)- and (1----6)-linked alpha-D-glucopyranosyl groups as acceptors in the glycogen synthase reaction.
Insoluble, light-sensitive polymers linked to maltose, maltotriose, a glycogen-branch point trisaccharide, and panose were synthesized and served in a comparative study as acceptors in the glycogen synthase (UDP-D-glucose:glycogen 4-alpha-D-glucosyltransferase, EC 2.4.1.11) reaction. The highest transfer rate was observed with the maltotrio polymer. Extending the acceptor linearly with (1----4)-linked alpha-D-glucopyranosyl residues improved the transfer, whereas (1----6)-linked alpha-D-glucopyranosyl branches decreased it.
Zehavi
U
U
Department of Biochemistry and Human Nutrition, Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel.
Herchman
M
M
Köpper
S
S
D002240:Carbohydrate Sequence; D005936:Glucans / Q000737:chemistry*; D006006:Glycogen Synthase / Q000378:metabolism*; D008320:Maltose / Q000737:chemistry*; D008969:Molecular Sequence Data; D011134:Polysaccharides / Q000378:metabolism*; D013379:Substrate Specificity; D014312:Trisaccharides / Q000737:chemistry*
D005936:Glucans; D011134:Polysaccharides; D014312:Trisaccharides; C008763:panose; C008317:maltotriose; D008320:Maltose; D006006:Glycogen Synthase