title: Lung and heart-lung transplantation: the state of the art.
abstract: Lung and heart-lung transplantation is one of the most rapidly evolving transplantation fields. Survival has been improving with better patient selection, better graft preservation, and better immunosuppression. This paper outlines criteria for patient selection, reviews the surgical options involving lung transplantation, and discusses factors influencing morbidity and survival in these patients. The Cleveland Clinic Foundation experience with these procedures is presented. Lung and heart-lung transplantation has emerged from the experimental realm to the therapeutic, and can now be offered as an effective treatment option to many patients with previously fatal heart and lung disorders.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, OH 44195-5066.
authors.forename: P M
authors.initials: PM
authors.lastname: McCarthy
authors.forename: T J
authors.initials: TJ
authors.lastname: Kirby
authors.forename: R D
authors.initials: RD
authors.lastname: White
authors.forename: T W
authors.initials: TW
authors.lastname: Rice
authors.forename: E R
authors.initials: ER
authors.lastname: Rosenkranz
authors.forename: A P
authors.initials: AP
authors.lastname: Baldyga
authors.forename: R
authors.initials: R
authors.lastname: Vargo
authors.forename: A C
authors.initials: AC
authors.lastname: Mehta
mesh_terms: D000075202:Contraindications; D006084:Graft Rejection; D006331:Heart Diseases / Q000601:surgery*; D016041:Heart-Lung Transplantation / Q000379:methods / Q000401:mortality / Q000502:physiology; D006801:Humans; D008171:Lung Diseases / Q000601:surgery*; D016040:Lung Transplantation / Q000379:methods / Q000401:mortality / Q000502:physiology; D009017:Morbidity; D011183:Postoperative Complications / Q000453:epidemiology; D015996:Survival Rate; D014019:Tissue Donors