IgM and IgG antibodies specific to rubella in child bearing women.
Three hundred fifty five pregnant women were tested for IgM and IgG type of antibodies by Enzyme Immuno Assay (EIA). Sero-positivity for IgM and IgG antibodies were 13% and 29% respectively. Of 212 pregnant women with abortion, 39 (18%) and 80 (38%) were sero-positive and of 143 pregnant women with normal reproductive performance, 7 (5%) and 23 (16%) were positive for IgM and IgG respectively. Premarital screening and vaccination of Sero-negative girls is recommended to reduce morbidity and mortality related to rubella virus.
Ahmed
M U
MU
Abbasi Shaheed Hospital, Karachi.
D000022:Abortion, Spontaneous / Q000209:etiology; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008875:Middle Aged; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology* / Q000276:immunology; D012307:Risk Factors; D012409:Rubella / Q000150:complications / Q000453:epidemiology* / Q000276:immunology; D012412:Rubella virus / Q000276:immunology; D016036:Seroepidemiologic Studies
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M