Hereditary haemorrhagic telangiectasia: a clinical analysis.
Data from 98 patients with hereditary haemorrhagic telangiectasia (HHT) are presented. All were symptomatic by 40 years of age and 62% by 16 years. Nose bleeding was the first symptom of disease in 90% of cases with mucocutaneous telangiectases appearing 5 to 20 years later. Complications of HHT are discussed and an age of onset curve given.
Porteous
M E
ME
Department of Human Genetics, University of Newcastle upon Tyne.
Burn
J
J
Proctor
S J
SJ
D000293:Adolescent; D000328:Adult; D000792:Angiography; D001165:Arteriovenous Malformations / Q000000981:diagnostic imaging; D001921:Brain / Q000098:blood supply; D004844:Epistaxis; D006801:Humans; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000453:epidemiology / Q000503:physiopathology*; D014057:Tomography, X-Ray Computed; D006113:United Kingdom / Q000453:epidemiology