title: Riboflavin requirements and exercise adaptation in older women.
abstract: The effects of exercise training on riboflavin requirements and of riboflavin intake on endurance were examined in 14 women, 50-67 y of age, who participated in a 10-wk, two-period crossover exercise study at two riboflavin intakes, 0.15 micrograms/kJ (0.6 micrograms/kcal) and 0.22 micrograms/kJ (0.9 micrograms/kcal). Subjects exercised 20-25 min/d, 6 d/wk, for 4-wk periods on a cycle ergometer at 75-85% of their maximal heart rate. Riboflavin status was assessed by measuring the erythrocyte glutathione reductase activity coefficient (EGRAC) and urinary riboflavin excretion. Physical performance was evaluated by using a walking treadmill test to determine maximal oxygen capacity (VO2max) and anaerobic threshold by gas exchange (ATGE). Exercise significantly affected riboflavin status as EGRAC increased (P less than 0.001) and riboflavin excretion decreased (P less than 0.01) in both groups. VO2max increased significantly with exercise (P less than 0.01). However, changes in VO2max (L/min) and ATGE with exercise training were not different in the two groups. Riboflavin requirements of older women increased with exercise training, but increased riboflavin intake did not enhance improvements in endurance.
authors.affiliation: Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853.
authors.forename: L R
authors.initials: LR
authors.lastname: Winters
authors.forename: J S
authors.initials: JS
authors.lastname: Yoon
authors.forename: H J
authors.initials: HJ
authors.lastname: Kalkwarf
authors.forename: J C
authors.initials: JC
authors.lastname: Davies
authors.forename: M G
authors.initials: MG
authors.lastname: Berkowitz
authors.forename: J
authors.initials: J
authors.lastname: Haas
authors.forename: D A
authors.initials: DA
authors.lastname: Roe
mesh_terms: D000368:Aged; D015308:Anaerobic Threshold / Q000502:physiology; D001823:Body Composition; D002149:Energy Intake; D004912:Erythrocytes / Q000201:enzymology*; D015444:Exercise / Q000502:physiology*; D005260:Female; D005980:Glutathione Reductase / Q000032:analysis*; D006801:Humans; D008875:Middle Aged; D009751:Nutritional Requirements; D010101:Oxygen Consumption / Q000502:physiology; D012256:Riboflavin / Q000008:administration & dosage* / Q000652:urine; D015431:Weight Loss / Q000502:physiology
chemical_list: D005980:Glutathione Reductase; D012256:Riboflavin