title: Noradrenergic innervation of vasopressin-containing neurons in the rat hypothalamic supraoptic nucleus.
abstract: The noradrenergic innervation of vasopressin (VP)-containing neurons in the supraoptic nucleus (SON) of the rat hypothalamus was studied electron microscopically by using double-labeling immunocytochemistry combining the pre-embedding peroxidase-anti-peroxidase method with post-embedding immunocolloidal gold staining. Noradrenaline-like immunoreactive axon terminals were found to make synaptic contacts with neurophysin II-like immunoreactive neurons in the SON. This provides morphological evidence for noradrenergic control of neuronal activity of VP-containing neurons at the SON level.
authors.affiliation: Department of Anatomy, Showa University School of Medicine, Tokyo, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Shioda
authors.forename: Y
authors.initials: Y
authors.lastname: Nakai
mesh_terms: D000320:Adrenergic Fibers / Q000737:chemistry / Q000648:ultrastructure*; D000818:Animals; D007150:Immunohistochemistry; D008297:Male; D016253:Microscopy, Immunoelectron; D009638:Norepinephrine / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains; D013495:Supraoptic Nucleus / Q000737:chemistry / Q000648:ultrastructure*; D013569:Synapses / Q000737:chemistry / Q000648:ultrastructure*; D014667:Vasopressins / Q000032:analysis*
chemical_list: D014667:Vasopressins; D009638:Norepinephrine