title: Esophageal stenting with a self-expandable metallic device: a preliminary study.
abstract: This study was designed to investigate the potential of the Gianturco-Rosch Z stent in the alimentary canal, using the rabbit esophagus as the animal model. Single stents were implanted in four animals, which were followed up for predetermined periods, lasting from 48 hours to 6 weeks. All the stents remained in place. A florid tissue reaction was noticed, initially manifesting primarily as submucosal cellular infiltration, and mucosal erosion. Over the ensuing six weeks, the acute changes gave way to mucosal regeneration, and the appearance of granulation tissue in the submucosa. The stented segments remained patent, and feeding difficulties were limited to the immediate post-procedure period. These preliminary results suggest that peristaltic activity is no contraindication to the use of Z stents, though measures to limit the tissue response need to be identified.
authors.affiliation: Department of Radiology, Nagoya University School of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Roy
authors.forename: S S
authors.initials: SS
authors.lastname: Baijal
authors.forename: T
authors.initials: T
authors.lastname: Ishiguchi
authors.forename: M
authors.initials: M
authors.lastname: Hirose
authors.forename: H
authors.initials: H
authors.lastname: Fukatsu
authors.forename: S
authors.initials: S
authors.lastname: Itoh
authors.forename: S
authors.initials: S
authors.lastname: Sakuma
authors.forename: K
authors.initials: K
authors.lastname: Kasai
mesh_terms: D000818:Animals; D004947:Esophagus / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D005069:Evaluation Studies as Topic; D008670:Metals; D011817:Rabbits; D011859:Radiography; D015607:Stents
chemical_list: D008670:Metals