Nocturnal asthma.
The nocturnal worsening of asthma is a common problem that can have significant related morbidity and mortality. There are many circadian biologic rhythms that contribute to the increased nocturnal bronchial reactivity and decrement in lung function. Therapy directed at the nocturnal aspect of this asthma process can produce marked improvement in symptoms and lung function.
Martin
R J
RJ
University of Colorado Health Sciences Center, Denver.
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D001249:Asthma / Q000097:blood / Q000150:complications / Q000503:physiopathology* / Q000628:therapy; D016535:Bronchial Hyperreactivity / Q000503:physiopathology; D002940:Circadian Rhythm / Q000502:physiology; D005764:Gastroesophageal Reflux / Q000150:complications / Q000503:physiopathology; D006801:Humans; D010100:Oxygen / Q000097:blood; D011175:Positive-Pressure Respiration; D012890:Sleep / Q000502:physiology*; D012891:Sleep Apnea Syndromes / Q000503:physiopathology; D013806:Theophylline / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D013806:Theophylline; D010100:Oxygen