Cyclosporine and its analogue SDZ IMM 125 mediate very similar effects on T-cell activation--a comparative analysis in vitro.
Baumann
G
G
Preclinical Research, Sandoz Pharma Ltd, Basel, Switzerland.
Andersen
E
E
Quesniaux
V
V
Eberle
M K
MK
D000591:Amino Acid Isomerases / Q000378:metabolism; D002352:Carrier Proteins / Q000378:metabolism; D016572:Cyclosporine / Q000494:pharmacology*; D003524:Cyclosporins / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007376:Interleukin-2 / Q000235:genetics / Q000378:metabolism; D008213:Lymphocyte Activation / Q000187:drug effects*; D008222:Lymphokines / Q000235:genetics; D019696:Peptidylprolyl Isomerase; D011401:Promoter Regions, Genetic; D011485:Protein Binding; D013601:T-Lymphocytes / Q000276:immunology*; D014158:Transcription, Genetic / Q000187:drug effects; D014407:Tumor Cells, Cultured / Q000378:metabolism
D002352:Carrier Proteins; D003524:Cyclosporins; D007376:Interleukin-2; D008222:Lymphokines; D016572:Cyclosporine; D000591:Amino Acid Isomerases; D019696:Peptidylprolyl Isomerase; C075935:SDZ IMM 125