Pleomorphic xanthoastrocytoma as a component of a cerebellar ganglioglioma: case report.
A 27-year old male patient underwent surgery for a cerebellar ganglioglioma in which a pleomorphic xanthoastrocytoma constituted the gliomatous element. Neither radiation nor chemotherapy was administered. The patient was well for 12 years and then he suffered a recurrence and underwent a gross total resection. Histological examination revealed a ganglioglioma with thrombosed blood vessels, areas of tumor necrosis, and scattered mitoses. These anaplastic changes, which were restricted to the glial component of the tumor, may herald a more aggressive clinical course. However, 11 months after the second operation, there have been no signs of tumor recurrence.
Lindboe
C F
CF
Department of Pathology, Trondheim University Hospital, Norway.
Cappelen
J
J
Kepes
J J
JJ
D000328:Adult; D001254:Astrocytoma / Q000473:pathology* / Q000601:surgery; D002455:Cell Division / Q000502:physiology; D002528:Cerebellar Neoplasms / Q000473:pathology* / Q000601:surgery; D002531:Cerebellum / Q000473:pathology; D002557:Cerebrospinal Fluid Shunts; D004730:Endothelium, Vascular / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D016609:Neoplasms, Second Primary / Q000473:pathology* / Q000601:surgery; D009447:Neuroblastoma / Q000473:pathology* / Q000601:surgery