[Profile of thyroid hormones in aging: evaluation of a hospitalized elderly population].
The aim of the study is to evaluate thyroid serum levels in a geriatric community to confirm the presence of a low T3 syndrome during normal ageing. The authors consider 413 subjects (125 male and 288 female) admitted to our Geriatric Division. The group affected by thyroid and extrathyroid disease (such us malnutrition, diabetes mellitus, renal failure, etc.) was withdrawn. In the selected patients (271) was operated a statistical evaluation to correlate the hormonal parameters (T3, T4, TSH, FT3, FT4) with age and sex. According to international literature, we confirm a progressive T4 and FT4 reduction (p less than 0.05) during ageing, both in male and in female. These data range within normal values. On the contrary, TSH shows no modifications with age and sex. Unlike all other parameters, T3 presents a more evident decrement with age, confirming a low T3 syndrome.
Lipponi
G
G
Divisione di Medicina Geriatrica, INRCA, Ancona.
Cadeddu
G
G
Lucantoni
C
C
Gasparrini
P M
PM
Spazzafumo
L
L
Gaetti
R
R
D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism*; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D013577:Syndrome; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood / Q000172:deficiency*
D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine
Profilo degli ormoni tiroidei nell'invecchiamento: valutazione su di una popolazione anziana ospedalizzata.