title: Major complications associated with extra-amniotic prostaglandin F2 alpha termination of the mid-trimester pregnancy.
abstract: Extra-amniotic prostaglandin F2 alpha (PGF2 alpha) termination of mid-trimester pregnancy can be associated with serious complications, defined for the purposes of this study as unintended major surgery or death as a result of the termination. A retrospective study of 319 such mid-trimester terminations at Johannesburg hospital revealed that 3 patients required hysterectomy, 1 developed a large tear of the posterior cervix and 1 died suddenly during the procedure. We are therefore considering changing our methods for second-trimester terminations.
authors.affiliation: Department of Obstetrics and Gynaecology, University of the Witwatersrand, Johannesburg.
authors.forename: F
authors.initials: F
authors.lastname: Guidozzi
authors.forename: M
authors.initials: M
authors.lastname: van der Griendt
authors.forename: D
authors.initials: D
authors.lastname: Israelstam
mesh_terms: D000028:Abortion, Induced / Q000009:adverse effects*; D000293:Adolescent; D000328:Adult; D015237:Dinoprost / Q000009:adverse effects*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D012189:Retrospective Studies
chemical_list: D015237:Dinoprost