Spatial attention in HIV-1 infection: a preliminary report.
In a preliminary study, 30 nondemented human immunodeficiency virus (HIV-1) seropositive subjects without acquired immunodeficiency syndrome and 14 seronegative controls performed a reaction time measure of spatial attention. Compared with controls, seropositive asymptomatic subjects showed normal facilitation of reaction time at short cue-target intervals when attention was precued, but symptomatic subjects were impaired. However, asymptomatic subjects showed no evidence of normal inhibition of attention at the cued location at longer cue-target intervals, suggesting possible subtler spatial attentional deficits in this group. Cognitive slowing in HIV-1 infection may have an attentional component, with possible involvement of both automatic and controlled processes.
Martin
E M
EM
Department of Neurology, University of California, Davis.
Sorensen
D J
DJ
Robertson
L C
LC
Edelstein
H E
HE
Chirurgi
V A
VA
D015526:AIDS Dementia Complex / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D000328:Adult; D001288:Attention / Q000502:physiology*; D006679:HIV Seropositivity / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D015497:HIV-1 / Q000472:pathogenicity*; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D009949:Orientation / Q000502:physiology*; D010364:Pattern Recognition, Visual / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology