Differential effects of right-sided and left-sided orchidectomy on lateral asymmetry of LHRH cells in the mouse brain.
Luteinizing hormone-releasing hormone (LHRH) immunoreactive cells were found to be more numerous in the right side of the brain than in the left in male mice. Bilateral orchidectomy or removal of the right testis decreased the number of LHRH cells, while removal of the left testis failed to cause any changes in the number of LHRH cells. The results indicated a clear left-right difference in the neuroendocrine regulation of gonadal function in male mice.
Inase
Y
Y
Department of Regulation Biology, Faculty of Science, Saitama University, Urawa, Japan.
Machida
T
T
D000818:Animals; D001923:Brain Chemistry / Q000502:physiology*; D007839:Functional Laterality / Q000502:physiology*; D007987:Gonadotropin-Releasing Hormone / Q000032:analysis*; D008297:Male; D051379:Mice; D009919:Orchiectomy / Q000379:methods; D013737:Testis / Q000502:physiology*
D007987:Gonadotropin-Releasing Hormone