title: Alterations in tympanic membrane appearance and middle ear function in 11-year-old children with complete unilateral cleft lip and palate compared with healthy age-matched subjects.
abstract: Forty-four 11-year-old children born with a complete unilateral cleft lip and palate were examined to determine the frequency and the extent of changes in the tympanic membrane and the middle ear function and compared with 16 healthy children of the same age. The incidence of hearing impairment, abnormal middle ear pressure, retraction of the pars flaccida and abnormal tympanic membrane appearance were 24, 44, 23 and 67% respectively among the patients while the same parameters in the control group were 0, 12.5, 6 and 12%. Previous grommet insertion in the patient group was statistically correlated to both tympanic membrane abnormality and abnormal middle ear pressure but, remarkably, no association was found between grommet insertion and hearing impairment. The poor middle ear function in the children with cleft lip and palate was probably a result of reduced Eustachian tube function.
authors.affiliation: Ear Nose and Throat Department, Aarhus University Hospital, Denmark.
authors.forename: T
authors.initials: T
authors.lastname: Ovesen
authors.forename: O
authors.initials: O
authors.lastname: Blegvad-Andersen
mesh_terms: D000158:Acoustic Impedance Tests; D000367:Age Factors; D001299:Audiometry; D002648:Child; D002971:Cleft Lip / Q000150:complications*; D002972:Cleft Palate / Q000150:complications*; D005260:Female; D006311:Hearing Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008297:Male; D016555:Matched-Pair Analysis; D015995:Prevalence; D014432:Tympanic Membrane / Q000473:pathology / Q000503:physiopathology