Alcoholism, hyponatraemia and central neurological damage: more than pontine myelinolysis?
Three patients with alcoholism and severe hyponatraemia are described. Permanent neurological damage occurred in each case with cerebral, cerebellar or pontine damage from infarction or haemorrhage following correction of the biochemical disturbance. No patient developed Central Pontine Myelinolysis (CPM), the condition usually associated with profound hyponatraemia and its correction.
Adamson
D J
DJ
Aberdeen Royal Infirmary, Foresterhill.
Laing
R B
RB
Nathwani
D
D
D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000150:complications*; D002543:Cerebral Hemorrhage / Q000175:diagnosis* / Q000209:etiology; D002544:Cerebral Infarction / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000150:complications*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed