title: Sensitization to the isothiazolinone biocide. Report of the Swiss Contact Dermatitis Research Group 1988-1990.
abstract: The rate of sensitization to isothiazolinones (Kathon CG) detected in Switzerland rose from 3.5% (out of 2,491 patients) in 1987 to 6.3% (out of 982 patients) in 1988 and 5.6% (out of 2,295 patients) in 1989-90. This rate of sensitization appears to be related to the more and more widespread use of isothiazolinone biocide in cosmetics, domestic products and in industry.
authors.affiliation: Clinique de Dermatologie, Hôpital cantonal, Genève, Switzerland.
authors.forename: N
authors.initials: N
authors.lastname: Hunziker
authors.forename: F
authors.initials: F
authors.lastname: Pasche
authors.forename: A
authors.initials: A
authors.lastname: Bircher
authors.forename: L
authors.initials: L
authors.lastname: Bruckner-Tuderman
authors.forename: T
authors.initials: T
authors.lastname: Hunziker
authors.forename: P
authors.initials: P
authors.lastname: Schmid
authors.forename: A
authors.initials: A
authors.lastname: Suard
authors.forename: H
authors.initials: H
authors.lastname: Suter
authors.forename: D
authors.initials: D
authors.lastname: Perrenoud
authors.forename: J
authors.initials: J
authors.lastname: Stäger
mesh_terms: D003358:Cosmetics / Q000009:adverse effects; D003877:Dermatitis, Contact / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D010328:Patch Tests; D011310:Preservatives, Pharmaceutical / Q000009:adverse effects*; D015995:Prevalence; D013557:Switzerland / Q000453:epidemiology; D013844:Thiazoles / Q000009:adverse effects*
chemical_list: D003358:Cosmetics; D011310:Preservatives, Pharmaceutical; D013844:Thiazoles; C037057:Kathon 886