Effects of tung oil on salivary viscosity and extent and incidence of dental caries in rats.
Increased salivary viscosity may be associated with an increase in dental caries. In order to examine this relationship, the caries level in rats was monitored following gastric intubation with tung oil which has been shown to significantly increase salivary viscosity. Tung oil intubation over an 8-week period significantly increased the salivary viscosity in rats as compared with deoinized water and corn oil intubation. The total number of carious lesions was significantly increased (p less than 0.05) in the tung oil intubated rats as compared with the two other groups. This increase in carious lesions was primarily associated with the smooth surfaces of the teeth. There was also a significant increase (p less than 0.05) in the extent of enamel and dentin involvement of the tung oil intubated rats as compared with the other two groups. Histologic examination of the submandibular glands revealed an increase in the amount of glycoprotein material in the convoluted granular tubules of the tung oil intubated rats as compared with the deionized water and corn oil intubated animals. Collectively, these results suggest that tung oil intubation is correlated with both increased salivary viscosity and increased smooth-surface dental caries, suggesting that the viscosity may be related to dental caries progression.
Biesbrock
A R
AR
Department of Oral Biology, School of Dentistry, Medical College of Georgia, Augusta.
Dirksen
T
T
Schuster
G
G
D000818:Animals; D003314:Corn Oil / Q000008:administration & dosage / Q000494:pharmacology; D003731:Dental Caries / Q000209:etiology* / Q000382:microbiology / Q000503:physiopathology; D005260:Female; D006023:Glycoproteins; D007441:Intubation, Gastrointestinal; D008297:Male; D010938:Plant Oils / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D012463:Saliva / Q000737:chemistry / Q000187:drug effects* / Q000502:physiology; D016986:Streptococcus sobrinus / Q000502:physiology; D013363:Submandibular Gland / Q000187:drug effects / Q000473:pathology; D014783:Viscosity; D014867:Water
D006023:Glycoproteins; D010938:Plant Oils; D014867:Water; C009612:tung oil; D003314:Corn Oil