Habituation to zipeprol hydrochloride during pregnancy.
Zipeprol hydrochloride is a synthetic antitussive agent that has shown little evidence of addictive potential in animal studies. Despite this, several reports of abuse and abuse-related over-dosage have been published. Abuse of this drug has now become a problem in the United States-Mexico border region. We report the specific case of a pregnant woman habituated to zipeprol without evidence of other drug abuse and an abstinence syndrome observed in her newborn infant.
Slobodkin
D
D
Department of Emergency Medicine, Texas Tech University RAHC, El Paso 79905.
Thompson
D
D
Levin
G
G
Jesurun
C A
CA
D000328:Adult; D000996:Antitussive Agents / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009357:Neonatal Abstinence Syndrome / Q000209:etiology*; D009460:Neurologic Examination / Q000187:drug effects; D010879:Piperazines / Q000009:adverse effects*; D011247:Pregnancy; D012307:Risk Factors
D000996:Antitussive Agents; D010879:Piperazines; C013341:zipeprol