Acute uric acid nephropathy in pregnancy.
BACKGROUND
Although uric acid clearance increases during gestation, uric acid nephropathy is a rare cause of acute renal failure in the pregnant woman.


METHODS
A 38-year-old woman experienced acute renal failure due to acute uric acid nephropathy at 30 weeks' gestation. The diagnosis was based on extreme hyperuricemia and an elevated uric acid-creatinine ratio. Treatment with forced diuresis, urine alkalinization, and mannitol infusion resulted in a prompt and complete recovery of renal function. The woman ultimately gave birth to a healthy child.


CONCLUSIONS
Acute uric acid nephropathy during pregnancy responds to conventional medical therapy.
Alexopoulos
E
E
First Department of Obstetrics and Gynecology, Aristotelian University of Thessaloniki, Hippokration General Hospital, Greece.
Tampakoudis
P
P
Bili
H
H
Mantalenakis
S
S
D058186:Acute Kidney Injury / Q000453:epidemiology / Q000209:etiology*; D000328:Adult; D005260:Female; D006801:Humans; D008423:Maternal Age; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology / Q000209:etiology*; D018566:Pregnancy, High-Risk; D014527:Uric Acid / Q000378:metabolism*
D014527:Uric Acid