title: Oesophageal carcinoma in Karachi.
abstract: Between January, 1979 to August, 1990, 107 histologically proven cases of oesophageal carcinoma were seen. The ages of the patients ranged from 19-85 years (mean 55 +/- 14 years) with a male to female ratio of 1.2:1. Majority (70%) of the cases belonged to lower socioeconomic group and 56% were migrants from India. History of tobacco chewing or smoking was present in 78% cases. In 54%, the lesion was located in the middle third of the oesophagus, followed by lower third in 44%. Histology showed squamous cell carcinoma in 86% and adenocarcinoma in 10% cases. Of the 19 cases followed, 16 underwent surgery and 3 received chemotherapy. Two cases died within 7 months following surgery and in 6 carcinomas recurred. All cases receiving chemotherapy died within 8 months of treatment.
authors.affiliation: PMRC Research Centre, Basic Medical Sciences Institute, Jinnah Postgraduate Medical Centre, Karachi.
authors.forename: W U
authors.initials: WU
authors.lastname: Ahmed
authors.forename: H
authors.initials: H
authors.lastname: Qureshi
authors.forename: E
authors.initials: E
authors.lastname: Alam
authors.forename: S J
authors.initials: SJ
authors.lastname: Zuberi
authors.forename: Q
authors.initials: Q
authors.lastname: Jamal
authors.forename: S M
authors.initials: SM
authors.lastname: Alam
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery; D002648:Child; D004938:Esophageal Neoplasms / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery; D005260:Female; D006801:Humans; D007194:India / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D010154:Pakistan / Q000453:epidemiology; D012307:Risk Factors; D012923:Social Class