An autopsy case of intravascular lymphomatosis (neoplastic angioendotheliomatosis) accompanied by high fever, hypertension and without focal sign.
A 75-year-old woman suffered from intermittent high-grade fever and hypertension without any focal sign. Serum lactic dehydrogenase (LDH) was markedly elevated. The fever was resistant to antibiotics and temporarily sensitive to prednisolone. She had heart failure and died. Postmortem examination revealed intravascular proliferation of B lymphocytes, indicative of the diagnosis of intravascular lymphomatosis. The clinical diagnosis is usually very difficult because of the absence of pathognomonic clinical manifestations.
Inooka
G
G
Department of Medicine, Jichi Medical School, Tochigi, Japan.
Ishikawa
S
S
Saito
T
T
Saito
K
K
Kamoshida
T
T
Kuzuya
T
T
D000368:Aged; D001402:B-Lymphocytes / Q000276:immunology / Q000473:pathology; D005260:Female; D005334:Fever / Q000150:complications; D006390:Hemangioendothelioma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D006973:Hypertension / Q000150:complications; D007770:L-Lactate Dehydrogenase / Q000097:blood; D016393:Lymphoma, B-Cell / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D014652:Vascular Diseases / Q000150:complications / Q000175:diagnosis* / Q000473:pathology
D007770:L-Lactate Dehydrogenase