Antitumor agents, 127. Bruceoside C, a new cytotoxic quassinoid glucoside, and related compounds from Brucea javanica.
Bruceoside C [5], a new quassinoid glucoside, and related compounds were isolated from Brucea javanica, and their structures were elucidated by spectral data. Bruceoside C showed potent cytotoxicities against KB, A-549, RPMI, and TE-671 tumor cells.
Fukamiya
N
N
Interdisciplinary Studies of Natural Environment, Faculty of Integrated Arts and Sciences, Hiroshima University, Japan.
Okano
M
M
Miyamoto
M
M
Tagahara
K
K
Lee
K H
KH
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D005900:Glaucarubin / Q000031:analogs & derivatives / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D009369:Neoplasms / Q000188:drug therapy / Q000473:pathology; D010946:Plants, Medicinal / Q000737:chemistry*; D036702:Quassins; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic; D036702:Quassins; C076182:bruceoside C; D005900:Glaucarubin