Benign and malignant breast pathology.
Research is focused on defining high-risk factors associated with the development of breast cancer and occult metastatic disease in node-negative patients. The interaction between hormones and growth factors is being diligently investigated, both in the genesis of breast cancer and in metastases. The effect of oral contraceptives on breast pathology remains under close scrutiny. Screening mammography for young women is proving to be of doubtful value.
Clark
R M
RM
Ontario Cancer Institute, Toronto, Canada.
D000367:Age Factors; D001943:Breast Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D003276:Contraceptives, Oral / Q000009:adverse effects; D066246:ErbB Receptors / Q000032:analysis; D005260:Female; D005348:Fibrocystic Breast Disease / Q000188:drug therapy; D007987:Gonadotropin-Releasing Hormone / Q000627:therapeutic use; D006801:Humans; D007150:Immunohistochemistry; D008327:Mammography / Q000592:standards; D008403:Mass Screening / Q000592:standards; D008408:Mastectomy / Q000592:standards; D008597:Menstrual Cycle; D009857:Oncogenes; D010298:Parity; D011237:Predictive Value of Tests; D011379:Prognosis; D015996:Survival Rate; D013629:Tamoxifen / Q000494:pharmacology / Q000627:therapeutic use; D013997:Time Factors
D003276:Contraceptives, Oral; D013629:Tamoxifen; D007987:Gonadotropin-Releasing Hormone; D066246:ErbB Receptors