title: Genetic markers in alcoholic liver cirrhosis.
abstract: 11 genetic markers were typed in 157 individuals suffering from alcoholic cirrhosis, and compared with a random sample of healthy individuals. No significant differences were found for transferrin, specific group component, orosomucoid, esterase D, phosphogluconate dehydrogenase and adenylate kinase. Strong associations between alcoholic cirrhosis and alpha-1-antitrypsin PI*Z allele, haptoglobin HP*1 allele and acid phosphatase ACP AC phenotype were observed. The biological significance of these associations and their relationships with the development of alcoholic cirrhosis are also discussed.
authors.affiliation: Institute of Legal Medicine, University of Santiago de Compostela, Spain.
authors.forename: M V
authors.initials: MV
authors.lastname: Lareu
authors.forename: A
authors.initials: A
authors.lastname: Alvarez-Prechous
authors.forename: C
authors.initials: C
authors.lastname: Pardiñas
authors.forename: L
authors.initials: L
authors.lastname: Concheiro
authors.forename: A
authors.initials: A
authors.lastname: Carracedo
mesh_terms: D000328:Adult; D000368:Aged; D005819:Genetic Markers / Q000235:genetics; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000235:genetics*; D008875:Middle Aged; D010641:Phenotype
chemical_list: D005819:Genetic Markers