Ataxia-telangiectasia in a child with vaccine-associated paralytic poliomyelitis.
Vaccine-acquired poliomyelitis developed in a nonimmunized 10-month-old boy. At age 4 years, ataxia-telangiectasia was recognized. We conclude that the occurrence of vaccine-related poliomyelitis warrants a detailed assessment of immunity, and that, in patients with ataxia-telangiectasia, the use of live vaccines may be hazardous, even in those with apparently normal immunity.
Pohl
K R
KR
Department of Neurology, University of British Columbia, Vancouver, Canada.
Farley
J D
JD
Jan
J E
JE
Junker
A K
AK
D001260:Ataxia Telangiectasia / Q000150:complications*; D006801:Humans; D007223:Infant; D008297:Male; D011051:Poliomyelitis / Q000209:etiology* / Q000635:transmission; D011055:Poliovirus Vaccine, Oral / Q000009:adverse effects*
D011055:Poliovirus Vaccine, Oral