title: The extracellular matrix in slow-growing tumors of the central nervous system.
abstract: This report describes and illustrates the results of the histopathological and histochemical investigation on five slow-growing tumors of the central nervous system: four meningiomas and an ependymoma of the spinal cord. We have studied, by means of polarizing microscopy, sections stained with picro-sirius red F3BA that enhance the birefringence of collagen and reticulum fibres. The heterogeneous behaviour of the distribution of the collagen let us conclude that the fibrillar component of the extracellular matrix have a scarce importance for the speed of growth of these tumours.
authors.affiliation: Cattedra di Neurochirurgia-Università di Reggio Calabria.
authors.forename: G
authors.initials: G
authors.lastname: Donato
authors.forename: A
authors.initials: A
authors.lastname: Lavano
authors.forename: G
authors.initials: G
authors.lastname: Volpentesta
authors.forename: F
authors.initials: F
authors.lastname: Habetswallner
authors.forename: G
authors.initials: G
authors.lastname: Martino
authors.forename: M
authors.initials: M
authors.lastname: Marotta
authors.forename: F A
authors.initials: FA
authors.lastname: Perino
authors.forename: C D
authors.initials: CD
authors.lastname: Signorelli
mesh_terms: D002455:Cell Division; D003094:Collagen / Q000032:analysis; D004806:Ependymoma / Q000737:chemistry / Q000473:pathology*; D005109:Extracellular Matrix / Q000737:chemistry / Q000648:ultrastructure*; D006801:Humans; D008577:Meningeal Neoplasms / Q000737:chemistry / Q000473:pathology*; D008579:Meningioma / Q000737:chemistry / Q000473:pathology*; D009363:Neoplasm Proteins / Q000032:analysis; D013120:Spinal Cord Neoplasms / Q000737:chemistry / Q000473:pathology*
chemical_list: D009363:Neoplasm Proteins; D003094:Collagen