title: Evaluation of hemorheologic variables as implications for exercise-induced pulmonary hemorrhage in racing thoroughbreds.
abstract: Hematologic and rheologic changes were examined in 49 Thoroughbreds before and after competitive racing. Mean postrace values for RBC count, hemoglobin concentration, and PCV increased by 58 to 61%, whereas blood viscosity increased 2 to 3 times. Postrace echinocyte numbers were 162% greater than prerace values. Smaller, but statistically significant, changes were found for mean corpuscular hemoglobin concentration, red cell distribution width, plasma total protein concentration, total WBC count, neutrophil count, and lymphocyte count. Variables measured did not predict whether a horse was a bleeder not treated with furosemide, a bleeder treated with furosemide, or a nonbleeder.
authors.affiliation: Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, St Paul 55108.
authors.forename: C B
authors.initials: CB
authors.lastname: McClay
authors.forename: D J
authors.initials: DJ
authors.lastname: Weiss
authors.forename: C M
authors.initials: CM
authors.lastname: Smith
authors.forename: B
authors.initials: B
authors.lastname: Gordon
mesh_terms: D000818:Animals; D001798:Blood Proteins / Q000032:analysis; D001809:Blood Viscosity; D004906:Erythrocyte Count / Q000662:veterinary; D004909:Erythrocyte Indices / Q000662:veterinary; D005665:Furosemide / Q000627:therapeutic use; D006400:Hematocrit / Q000662:veterinary; D006454:Hemoglobins / Q000032:analysis; D006470:Hemorrhage / Q000097:blood / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary*; D006734:Horse Diseases / Q000097:blood* / Q000188:drug therapy / Q000209:etiology; D006736:Horses; D007958:Leukocyte Count / Q000662:veterinary; D008171:Lung Diseases / Q000097:blood / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary*; D005082:Physical Exertion
chemical_list: D001798:Blood Proteins; D006454:Hemoglobins; D005665:Furosemide