A gamma-lactone immunosuppressant inhibits the generation of macrophage killer cells and prolongs skin allograft survival in the rat.
Ishibashi
M
M
Department of Urology, Osaka University Medical School, Japan.
Saijyo
T
T
Tamura
N
N
Moutabarrik
A
A
Kameoka
H
H
Jiang
H
H
Takahara
S
S
Kokado
Y
Y
Takano
Y
Y
D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D006085:Graft Survival / Q000187:drug effects*; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology* / Q000627:therapeutic use; D066298:In Vitro Techniques; D007694:Killer Cells, Natural / Q000187:drug effects / Q000276:immunology; D007783:Lactones / Q000627:therapeutic use*; D008213:Lymphocyte Activation / Q000187:drug effects; D008264:Macrophages / Q000187:drug effects / Q000276:immunology; D051381:Rats; D016038:Skin Transplantation / Q000276:immunology*
D007166:Immunosuppressive Agents; D007783:Lactones; D015107:4-Butyrolactone