[Diminution of epidermal growth factor in saliva of patients with carcinoma of the oropharynx].
EGF, the Epidermal Growth Factor which is found ubiquitous in the human body can also be detected in saliva and increases in general proliferation and differentiation of epithelial cells which enables mucosa regeneration to maintain their protective function. In this study concentrations of EGF in saliva of smokers and patients with carcinoma of the oropharynx were examined. Both groups showed a decreased concentration compared to non smokers. We studied also secretion of EGF in saliva after smoking. Only the group of non smokers showed a transient elevation of EGF.
Bergler
W
W
Clínica Universitaria de ORL, Klinikum Mannheim Universidad, Heidelberg, Alemania.
Petroianu
G
G
Metzler
R
R
D004815:Epidermal Growth Factor / Q000378:metabolism*; D006801:Humans; D009959:Oropharyngeal Neoplasms / Q000378:metabolism*; D012463:Saliva / Q000378:metabolism*; D012907:Smoking / Q000378:metabolism*
D004815:Epidermal Growth Factor
Disminución del factor de crecimiento epidérmico en la saliva en pacientes con carcinoma de la orofaringe.