Renal transplantation for treatment of end-stage renal failure in cats.
Renal transplantation was performed as treatment of end-stage renal failure in 23 cats. Twenty-two cats had chronic renal disease and 1 cat had acute renal disease associated with ethylene glycol-induced toxicosis. Sixteen cats were discharged from the hospital. Nine survived a mean of 8.4 +/- 6.5 months, and 7 cats continue to survive at the time of this report (mean 12.6 months). Seven cats died within 2 weeks of surgery. All renal allografts were obtained from unrelated blood-crossmatch-compatible donors. No deaths were attributable to acute renal allograft rejection, demonstrating the successful maintenance of renal allografts by use of cyclosporine and prednisolone immunosuppression in cats.
Gregory
C R
CR
Department of Surgery, School of Veterinary Medicine, University of California, Davis 95616.
Gourley
I M
IM
Kochin
E J
EJ
Broaddus
T W
TW
D000714:Anastomosis, Surgical; D000818:Animals; D002371:Cat Diseases / Q000601:surgery*; D002415:Cats; D005260:Female; D007084:Iliac Vein / Q000601:surgery; D007165:Immunosuppression Therapy / Q000662:veterinary; D007676:Kidney Failure, Chronic / Q000601:surgery / Q000662:veterinary*; D016030:Kidney Transplantation / Q000662:veterinary*; D008297:Male; D009392:Nephrectomy / Q000662:veterinary; D011182:Postoperative Care / Q000662:veterinary; D011183:Postoperative Complications / Q000401:mortality / Q000662:veterinary; D012082:Renal Veins / Q000601:surgery; D014019:Tissue Donors; D016896:Treatment Outcome; D014517:Ureteral Obstruction / Q000209:etiology / Q000601:surgery / Q000662:veterinary