The effect of nerve blockade on forearm and finger skin blood flow during body heating and cooling.
To determine the role of the active cutaneous vasodilatator response in forearm and finger skin, direct assessment of only skin blood flow was performed before and after musculocutaneous and median nerve blockade during whole body heating and cooling. Forearm laser Doppler flow (LDF forearm), forearm heat thermal clearance (HTC forearm), and finger laser Doppler flow (LDF finger) were monitored in the nerve blocked skin and contralateral untreated skin (control). In the pre-blockade period, no significant differences were found between experimental and control arm skin. After nerve block a significant increase occurred only in LDF finger, which rose from 4.3 +/- 0.6 to 6.0 +/- 0.5 volts (p less than 0.05). During whole body heating LDF forearm and HTC forearm increased significantly on both arms. The increase in LDF forearm was greater (p less than 0.05) in control (18.3 +/- 1.2 volts) than in nerve blocked skin (14.6 +/- 1.8 volts) and occurred earlier. The same tendency was observed in HTC forearm between nerve blocked skin (0.522 +/- 0.06 W.m-1.degrees C-1) and control 0.671 +/- 0.037 W.m-1.degrees C-1) (NS). LDF raise up to 6.6 +/- 0.5 and 6.8 +/- 0.5 volts in the blocked finger and in the control respectively. During cooling LDF finger in the control decreased to 1.3 +/- 0.1 volt and was significantly (p less than 0.05) lower than in the resting period, and lower than that in the nerve blocked finger (3.4 +/- 0.8 volts) (p less than 0.05). We conclude that the active vasodilatator system plays an important role as far as the timing and the amplitude of the cutaneous vasodilatator response to whole body heating in the forearm but not in the finger. At thermal neutrality, the vascular vasoconstrictor tone is high to the finger but not to the forearm. The vasoconstrictor response to cooling occurred only in the finger.
Saumet
J L
JL
Laboratoire de Physiologie et d'Explorations Vasculaires, C.H.R.U., Angers, France.
Degoute
C S
CS
Saumet
M
M
Abraham
P
P
D000328:Adult; D001340:Autonomic Nerve Block; D001833:Body Temperature Regulation / Q000502:physiology*; D003080:Cold Temperature; D005260:Female; D005385:Fingers / Q000098:blood supply* / Q000294:innervation; D005542:Forearm / Q000098:blood supply* / Q000294:innervation; D006439:Hemodynamics; D006358:Hot Temperature; D006801:Humans; D008297:Male; D008475:Median Nerve / Q000502:physiology; D008833:Microcirculation; D012039:Regional Blood Flow; D012867:Skin / Q000098:blood supply* / Q000294:innervation; D014666:Vasomotor System / Q000502:physiology*