title: Prokinetic agents.
abstract: Prokinetic agents are medications that promote gastrointestinal motility. This article reflects the current state of our understanding of their mechanisms of action and their clinical utility in treating disorders of gastrointestinal motility, including gastroesophageal reflux, gastroparesis, small-intestinal dysmotility, and constipation.
authors.affiliation: Division of Gastroenterology and Hepatology, University of Pittsburgh School of Medicine, Pennsylvania.
authors.forename: J C
authors.initials: JC
authors.lastname: Reynolds
authors.forename: P E
authors.initials: PE
authors.lastname: Putnam
mesh_terms: D001549:Benzamides / Q000378:metabolism; D018492:Dopamine Antagonists; D005746:Gastric Emptying / Q000187:drug effects; D005764:Gastroesophageal Reflux / Q000188:drug therapy; D005765:Gastrointestinal Agents / Q000494:pharmacology*; D005767:Gastrointestinal Diseases / Q000188:drug therapy; D005769:Gastrointestinal Motility / Q000187:drug effects*; D006801:Humans; D008787:Metoclopramide / Q000627:therapeutic use; D010277:Parasympathomimetics / Q000378:metabolism; D011182:Postoperative Care
chemical_list: D001549:Benzamides; D018492:Dopamine Antagonists; D005765:Gastrointestinal Agents; D010277:Parasympathomimetics; D008787:Metoclopramide