Fos expression in the trigeminal sensory nuclei after a chemical lesion of the lower lip mucosa.
C-fos containing neurons were investigated in the trigeminal sensory nuclear complex and in the dorsal horns of the cervical spinal cord (C1-C2) of the rat after a chemical noxious stimulus was applied to the lower lip mucosa. Numerous labelled neuronal nuclei were detected in the dorsolateral area of the caudal half of the trigeminal nucleus interpolaris, and in Rexed's laminae I-IIo of the dorsomedial area of the trigeminal nucleus caudalis and rostral C1. A few c-fos-labelled neurons were observed in laminae IIi and V. No Fos expression was detected in the trigeminal oral and principal nuclei.
Segade
L A
LA
Department of Morphological Sciences, Faculty of Medicine, University of Santiago de Compostela, Spain.
Relova
J L
JL
Gallego
R
R
D000085:Acetates / Q000633:toxicity*; D019342:Acetic Acid; D000818:Animals; D001933:Brain Stem / Q000502:physiology; D015870:Gene Expression / Q000187:drug effects; D016762:Genes, fos; D008046:Lip; D008297:Male; D009061:Mouth Mucosa / Q000187:drug effects / Q000502:physiology*; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D013116:Spinal Cord / Q000502:physiology*; D014275:Trigeminal Caudal Nucleus / Q000502:physiology; D014279:Trigeminal Nucleus, Spinal / Q000502:physiology*
D000085:Acetates; D019342:Acetic Acid