title: Coronary angioplasty performed with gradual and prolonged inflation using a perfusion balloon catheter: procedural success and restenosis rate.
abstract: The results of routine coronary angioplasty using gradual and prolonged balloon inflation with a perfusion balloon catheter were evaluated. One hundred forty patients were treated with inflation of the balloon to 6 atm over 3 minutes, with a median inflation time of 15 minutes. The procedural success rate (residual stenosis less than or equal to 50%) was 99%. In-hospital major complications occurred in five patients (3.6%), with one patient experiencing a periprocedural infarction, three patients requiring bypass surgery for abrupt closure, and one patient dying after elective bypass surgery following previous successful angioplasty of a culprit lesion. The restenosis rate in the 117 patients with angiographic follow-up (87% of those eligible) was 42%. Thus gradual and prolonged inflation using a perfusion balloon catheter resulted in a high procedural success rate and a restenosis rate similar to that reported in large studies of patients treated with standard angioplasty. These results warrant further study using a prospective randomized trial design.
authors.affiliation: Department of Medicine, Duke University Medical Center, Durham, N.C.
authors.forename: A N
authors.initials: AN
authors.lastname: Tenaglia
authors.forename: P J
authors.initials: PJ
authors.lastname: Quigley
authors.forename: D J
authors.initials: DJ
authors.lastname: Kereiakes
authors.forename: C W
authors.initials: CW
authors.lastname: Abbottsmith
authors.forename: H R
authors.initials: HR
authors.lastname: Phillips
authors.forename: J E
authors.initials: JE
authors.lastname: Tcheng
authors.forename: D
authors.initials: D
authors.lastname: Rendall
authors.forename: E M
authors.initials: EM
authors.lastname: Ohman
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D003251:Constriction, Pathologic / Q000000981:diagnostic imaging / Q000628:therapy; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010477:Perfusion / Q000295:instrumentation; D012008:Recurrence; D013997:Time Factors; D016896:Treatment Outcome