title: An analysis of the uncertainties in estimates of radon-induced lung cancer.
abstract: A recent report by the National Academy of Sciences estimates that the radiation dose to the bronchial epithelium, per working level month (WLM) of radon daughter exposure, is about 30% lower for residential exposures than for exposures received in underground mines. Adjusting the previously published BEIR IV radon risk model accordingly, the unit risk for indoor exposures of the general population is about 2.2 x 10(-4) lung cancer deaths (lcd)/WLM. Using results from EPA's National Residential Radon Survey, the average radon level is estimated to be about 1.25 pCi/L, and the annual average exposure about 0.242 WLM. Based on these estimates, 13,600 radon-induced lcd/yr are projected for the United States. A quantitative uncertainty analysis was performed, which considers: statistical uncertainties in the epidemiological studies of radon-exposed miners; the dependence of risk on age at, and time since, exposure; the extrapolation of risk estimates from mines to homes based on comparative dosimetry; and uncertainties in the radon daughter levels in homes and in the average residential occupancy. Based on this assessment of the uncertainties in the unit risk and exposure estimates, an uncertainty range of 7000-30000 lcd/yr is derived.
authors.affiliation: Office of Radiation Programs, U.S. Environmental Protection Agency, Washington, D.C. 20460.
authors.forename: J S
authors.initials: JS
authors.lastname: Puskin
mesh_terms: D000328:Adult; D000367:Age Factors; D002648:Child; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000209:etiology*; D008297:Male; D008906:Mining; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D009784:Occupational Diseases / Q000209:etiology; D011829:Radiation Dosage; D011886:Radon / Q000009:adverse effects*; D012307:Risk Factors
chemical_list: D011886:Radon