Theophylline--an alternative therapy for bradyarrhythmia in the elderly.
Treating elderly debilitated patients with symptomatic bradyarrhythmia may be difficult. Traditional therapy includes use of limited resources (intensive care unit monitoring) and expensive interventions (permanent pacemaker insertion). When a pacemaker is not ideal or appropriate, yet intervention is desired to improve quality of life, theophylline may be a safe and effective alternative therapy. We expanded this use of theophylline in a series of 11 patients admitted 14 consecutive times with hemodynamically compromising bradyarrhythmias, including atropine-resistant complete heart block with idioventricular rhythm. Three patients experienced deterioration of status and recurrence of bradycardia with the withdrawal or reduction of theophylline, and subsequent recovery of heart rate and conduction with its resumption.
Kragie
L
L
Department of Medicine, School of Medicine, State University of New York, Buffalo 14260.
Sekovski
B
B
D000368:Aged; D000369:Aged, 80 and over; D001919:Bradycardia / Q000188:drug therapy* / Q000503:physiopathology; D004562:Electrocardiography; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006769:Hospitals, General; D006801:Humans; D008297:Male; D009518:New York; D013806:Theophylline / Q000097:blood / Q000627:therapeutic use*
D013806:Theophylline