title: Polymorphisms of alpha-1-acid (orosomucoid), alpha-2-HS-glycoproteins and alpha-1-B among the Parsis of India.
abstract: Genetic polymorphisms of plasma alpha 1-acid glycoprotein (oro-somucoid, ORM), alpha 2-HS-glycoprotein (A2HS) and alpha 1-B-glycoprotein (alpha 1B) were studied in a group of Parsis in Bombay, India. The frequencies of ORM1*1, ORM1*2 and ORM1*3 were found to be 0.636, 0.356 and 0.008, respectively. A2HS*1, A2HS*2 and A2HS*3 frequencies were 0.855, 0.135 and 0.010, while the frequencies of A1B*1 and A1B*2 were 0.881 and 0.119, respectively. The phenotype distribution at all three loci was at Hardy-Weinberg equilibrium. The ORM2 locus was monomorphic in the Parsis.
authors.affiliation: Department of Paediatrics (Genetics Division), National University of Singapore.
authors.forename: N
authors.initials: N
authors.lastname: Saha
authors.forename: J V
authors.initials: JV
authors.lastname: Undevia
authors.forename: R K
authors.initials: RK
authors.lastname: Juneja
authors.forename: B
authors.initials: B
authors.lastname: Gahne
authors.forename: J S
authors.initials: JS
authors.lastname: Tay
mesh_terms: D000483:Alleles; D001798:Blood Proteins / Q000235:genetics*; D005006:Ethnicity; D005787:Gene Frequency; D006023:Glycoproteins; D006801:Humans; D007136:Immunoglobulins; D007194:India; D007492:Iran / Q000208:ethnology; D009961:Orosomucoid / Q000235:genetics*; D011110:Polymorphism, Genetic; D012067:Religion; D060749:alpha-2-HS-Glycoprotein
chemical_list: C048566:A1BG protein, human; C556354:AHSG protein, human; D001798:Blood Proteins; D006023:Glycoproteins; D007136:Immunoglobulins; D009961:Orosomucoid; D060749:alpha-2-HS-Glycoprotein