[The antigenic and allergenic properties of an extract from the house dust mite Dermatophagoides farinae].
To evaluate the antigenic composition and allergenic activity of D. farinae extracts, the methods of rocket and cross immunoelectrophoresis, gel chromatography and the inhibition of the radioallergosorbent test have been used. The presence of 9-20 antigenic components has been established. The fractions of the extract with a molecular weight of 10-200 kD possessed the highest capacity of inhibiting the binding of specific IgE antibodies from the pool of sera from patients sensitized to D. farinae.
Emel'ianova
O Iu
OIu
Perova
N A
NA
Golysheva
M A
MA
Berzhets
V M
VM
D000485:Allergens / Q000032:analysis* / Q000302:isolation & purification; D000818:Animals; D000941:Antigens / Q000032:analysis* / Q000302:isolation & purification; D002850:Chromatography, Gel / Q000379:methods; D004391:Dust; D007122:Immunoelectrophoresis / Q000379:methods; D008925:Mites / Q000276:immunology*; D008970:Molecular Weight; D011852:Radioallergosorbent Test / Q000379:methods
D000485:Allergens; D000941:Antigens; D004391:Dust
Antigennye i allergennye svoĭstva ékstrakta iz kleshcheĭ domashneĭ pyli Dermatophagoides farinae.