[Therapy of chronic viral hepatitis with recombinant interferon-alpha].
Long term treatment with interferon alpha is the only established therapy for chronic viral hepatitis so far. Depending on the type of viral hepatitis the response rate to interferon alpha is between 15 and 40%. These results can be improved by an appropriate selection of patients and possibly by combination therapy with other immunomodulatory and antiviral substances. The optimal dose in chronic hepatitis B is 5 Mega Units (MU) interferon alpha every other day for 6 months and in hepatitis C 3 MU every other day over 6 months.
Ferenci
P
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Klinischen Abteilung Gastroenterologie und Hepatologie, Universitätsklinik für Innere Medizin IV, Wien.
D006508:Hepatitis Antibodies / Q000032:analysis; D006526:Hepatitis C / Q000276:immunology / Q000628:therapy*; D003699:Hepatitis D / Q000276:immunology / Q000628:therapy*; D006521:Hepatitis, Chronic / Q000276:immunology / Q000628:therapy*; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use*; D011994:Recombinant Proteins
D006508:Hepatitis Antibodies; D007370:Interferon Type I; D011994:Recombinant Proteins
Therapie der chronischen Virushepatitis mit rekombinantem Interferon-alpha.