title: Long-term results of infrainguinal revascularization with polytetrafluoroethylene: a ten-year experience.
abstract: Two hundred fifty-eight patients underwent 322 infrainguinal revascularizations with use of polytetrafluoroethylene (PTFE) between 1978 and 1988. The indication was limb salvage in 190 (59%) reconstructions. Two hundred nineteen (68%) were above-knee, and 75 (23%) were below-knee femoropopliteal bypasses. Twenty-eight (8.6%) were femoral-infrapopliteal bypasses, all done for limb salvage. Follow-up ranged from 24 to 144 months (mean, 66 months). The perioperative mortality rate (1 to 30 days) was 3.4% (9 patients), with no significant difference according to indication (2.9% vs 3.7%). Actuarial primary patency at 8 years for the entire series of femoropopliteal bypasses was 53% (above knee 53%; below knee 39%; p less than 0.05), and improved with additional procedures for a secondary patency of 72%. Femoropopliteal bypasses done for severe claudication had an 8-year actuarial primary patency of 63%, compared with 38% for limb salvage (p less than 0.02). Actuarial limb salvage in the latter group at 8 years was 66%. Femoral-infrapopliteal reconstructions with PTFE had a significantly lower primary patency at 3 years (22%, with a 37% limb salvage). Sixty-four percent of the failures for all reconstructions (N = 111) occurred within 12 months, with remarkable stabilization of patency curves beyond that interval. This experience represents the largest reported series of PTFE reconstruction with longest follow-up to date and may serve as a basis for comparison of other conduits. These results suggest an important role for PTFE in femoropopliteal revascularization and a limited role of this prosthetic conduit in femoral-infrapopliteal arterial reconstructions.
authors.affiliation: Vascular Surgery Section, University of California Los Angeles School of Medicine 90024-6904.
authors.forename: W J
authors.initials: WJ
authors.lastname: Quiñones-Baldrich
authors.forename: A A
authors.initials: AA
authors.lastname: Prego
authors.forename: R
authors.initials: R
authors.lastname: Ucelay-Gomez
authors.forename: J A
authors.initials: JA
authors.lastname: Freischlag
authors.forename: S S
authors.initials: SS
authors.lastname: Ahn
authors.forename: J D
authors.initials: JD
authors.lastname: Baker
authors.forename: H I
authors.initials: HI
authors.lastname: Machleder
authors.forename: W S
authors.initials: WS
authors.lastname: Moore
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001157:Arterial Occlusive Diseases / Q000503:physiopathology / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D005260:Female; D005263:Femoral Artery / Q000601:surgery; D006801:Humans; D007866:Leg / Q000098:blood supply / Q000601:surgery*; D015993:Life Tables; D008297:Male; D008875:Middle Aged; D011138:Polytetrafluoroethylene; D011150:Popliteal Artery / Q000601:surgery; D012189:Retrospective Studies; D014654:Vascular Patency
chemical_list: D011138:Polytetrafluoroethylene