Stevisalioside A, a novel bitter-tasting ent-atisene glycoside from the roots of Stevia salicifolia.
A new acetylated ent-atisene glycoside, stevisalioside A [1], has been isolated as a bitter-tasting principle from Stevia salicifolia roots. The structure was established by the interpretation of spectral data, with the nmr assignments of this compound being based on 1H-1H COSY, 1H-13C HETCOR, and selective INEPT experiments. A rearrangement product 4 of the aglycone moiety obtained by alkaline hydrolysis supported the structure of 1. This is the first report of the occurrence of an atisane-type diterpene from the genus Stevia.
Mata
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Departamento de Farmacia, Facultad de Química, Universidad Nacional Autónoma de México, México D.F.
Rodríguez
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Pereda-Miranda
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Kaneda
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N
Kinghorn
A D
AD
D002240:Carbohydrate Sequence; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D013649:Taste; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism
D006027:Glycosides; D014315:Triterpenes; C076338:stevisalioside A