title: [Parahemophilia. Study in a family of 3 generations].
abstract: Three generations of a family with congenital deficit of factor V are reported. Those subjects showing symptoms were heterozygous. The transmission of the disease appears to be autosomal recessive. From a clinical standpoint, the patients suffered moderate haemorrhages, mostly affecting mucosae, which became severe on occasions, chiefly after labour. Isolated factor V rates did not correlate with the severity of bleeding. The different variants reported in the literature are commented. Transfusion of fresh-frozen plasma seems and adequate therapeutical approach for this disorder.
authors.affiliation: Hospital Santa María Madre, Servicio de Hematología y Hemoterapia, Orense.
authors.forename: M C
authors.initials: MC
authors.lastname: Hernández
authors.forename: P
authors.initials: P
authors.lastname: Vila
authors.forename: M
authors.initials: M
authors.lastname: Alvarez
mesh_terms: D005166:Factor V Deficiency / Q000235:genetics*; D006801:Humans; D008297:Male; D010375:Pedigree
vernacular_title: Parahemofilia. Estudio en una familia de tres generaciones.