title: Breast carcinoma simulating fibroadenoma or fibrocystic change by fine-needle aspiration. A study of 16 cases.
abstract: The cytologic features of fine-needle aspiration specimens from 16 breast carcinomas that closely simulated benign lesions were analyzed and compared to smears from fibroadenomas and fibrocystic change. No combination of features was found that accurately separated all benign and malignant cases. Many nuclei with discernible small nucleoli in smears with many single bipolar nuclei indicated a benign lesion, whereas nuclear hyperchromasia indicated a malignant one.
authors.affiliation: Department of Pathology, University of Vermont, Burlington 05405.
authors.forename: L A
authors.initials: LA
authors.lastname: Rogers
authors.forename: K R
authors.initials: KR
authors.lastname: Lee
mesh_terms: D000232:Adenofibroma / Q000473:pathology*; D000293:Adolescent; D000328:Adult; D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000473:pathology*; D002277:Carcinoma / Q000473:pathology*; D002466:Cell Nucleolus / Q000648:ultrastructure; D003937:Diagnosis, Differential; D005260:Female; D005348:Fibrocystic Breast Disease / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D010858:Pigmentation; D012044:Regression Analysis