title: [Antibiotic sensitivity of forty-four strains of group EF4 bacteria: study of minimum inhibitory concentrations using the agar dilution method].
abstract: EF4 bacteria are found in animal saliva and may contaminate bite wounds. Minimum inhibitory concentrations of 36 antimicrobials against 44 EF4 strains were determined using dilution in Mueller-Hinton agar. EF4 bacteria were susceptible to aminopenicillins, carboxypenicillins, ureidopenicillins, third-generation cephalosporins, fluoroquinolones, rifampicin, and trimethoprime-sulfamethoxazole. Susceptibility was intermediate for penicillin G, low for macrolides and variable for aminoglycosides. EF4 bacteria were resistant to lincomycin and trimethoprime. Routine prophylactic treatment of bite-induced Pasteurella infections using an aminopenicillin or a cycline also protects against EF4 infection of the wound.
authors.affiliation: Laboratoire de Bactériologie, Hôpital Central, CHU, Nancy, France.
authors.forename: C
authors.initials: C
authors.lastname: Lion
authors.forename: P
authors.initials: P
authors.lastname: de Monchy
authors.forename: M
authors.initials: M
authors.lastname: Weber
authors.forename: M C
authors.initials: MC
authors.lastname: Conroy
authors.forename: F
authors.initials: F
authors.lastname: Mory
authors.forename: J C
authors.initials: JC
authors.lastname: Burdin
mesh_terms: D042462:4-Quinolones; D000617:Aminoglycosides; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000890:Anti-Infective Agents / Q000494:pharmacology*; D002701:Chloramphenicol / Q000494:pharmacology; D015169:Colony Count, Microbial; D004305:Dose-Response Relationship, Drug; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D066298:In Vitro Techniques; D007769:Lactams; D018942:Macrolides; D008826:Microbial Sensitivity Tests / Q000379:methods; D013754:Tetracyclines / Q000494:pharmacology
chemical_list: D042462:4-Quinolones; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D007769:Lactams; D018942:Macrolides; D013754:Tetracyclines; D002701:Chloramphenicol
vernacular_title: Sensibilité aux antibiotiques de quarante-quatre souches de bactéries du groupe EF4: étude des concentrations minimales inhibitrices par dilution en gélose.