title: Measurement of blood flow in the parameatal foreskin flap for urethroplasty in hypospadias repair.
abstract: During the one-stage repair of hypospadias the blood flow of the parameatal-based foreskin flap was measured in 30 patients by using laser Doppler velocimetry. The mean blood flow in the penile foreskin was estimated to be 15 ml/min/100 g and it increased to 150-200% after the induction of anesthesia, and then decreased to 72% at the tip of the created parameatal foreskin flap. Topical application of papaverine hydrochloride restored the flow to the preincision level in half of the cases. The parameatal foreskin flap, both in the form of a manta-wing and in extended circumferential form, appears to have an enough microcirculation suitable for one-stage repair (OUPF II and OUPF IV, respectively) of hypospadias.
authors.affiliation: Department of Urology, Hokkaido University School of Medicine, Sapporo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Nonomura
authors.forename: T
authors.initials: T
authors.lastname: Koyanagi
authors.forename: K
authors.initials: K
authors.lastname: Imanaka
authors.forename: Y
authors.initials: Y
authors.lastname: Asano
mesh_terms: D002648:Child; D002675:Child, Preschool; D006801:Humans; D007021:Hypospadias / Q000601:surgery*; D007834:Lasers; D008297:Male; D008833:Microcirculation / Q000187:drug effects / Q000502:physiology; D010208:Papaverine / Q000494:pharmacology; D010413:Penis / Q000098:blood supply*; D012039:Regional Blood Flow; D013524:Surgical Flaps; D014521:Urethra / Q000601:surgery*
chemical_list: D010208:Papaverine