title: Overberg research projects. XII. The efficacy of an albendazole slow-release capsule in the control of nematode parasites of sheep.
abstract: Albendazole intra-ruminal slow-release capsules (SRC) administered to sheep grazing on irrigated pastures in the southern Cape Province, controlled Trichostrongylus for 91 d and Haemonchus and Teladorsagia for 61 d. Treating sheep with the SRC at 47 to 61 d intervals over a period of 10 months, significantly (P less than 0.05) reduced the infective potential of the pasture. Compared with sheep which received 2 disophenol and 3 broad spectrum anthelmintic treatments during the same period, the SRC reduced the infective potential of the pasture by 71.6%, while weekly drenching with albendazole over the same period, resulted in a significant (P less than 0.05) increase (73.4%) in the infective potential of the pasture.
authors.affiliation: Department of Parasitology, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, Republic of South Africa.
authors.forename: J P
authors.initials: JP
authors.lastname: Louw
authors.forename: R K
authors.initials: RK
authors.lastname: Reinecke
mesh_terms: D015766:Albendazole / Q000008:administration & dosage* / Q000627:therapeutic use; D000818:Animals; D002214:Capsules; D003692:Delayed-Action Preparations; D005260:Female; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary; D009349:Nematode Infections / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary*; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy* / Q000517:prevention & control
chemical_list: D002214:Capsules; D003692:Delayed-Action Preparations; D015766:Albendazole