[Effect of mytilane, a bioglycan from the mussel Crenomytilus grayanus, on the course and outcome of experimental flu infection].
Materials characterizing the antiviral activity of Mytilane, manifested by the protection of 50-60% of mice infected with the lethal dose of influenza virus and by a decrease in the severity of pathological changes in the lungs of mice, are presented. The inhibiting activity of Mytilane with respect to the reproduction of influenza virus in vivo and in vitro under experimental conditions is demonstrated.
Tsybul'skiĭ
A V
AV
Isachkova
L M
LM
Ovodova
R G
RG
Glazkova
V E
VE
Besednova
N N
NN
Orlova
T G
TG
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000818:Animals; D049872:Bivalvia / Q000737:chemistry*; D009980:Influenza A virus / Q000502:physiology; D008168:Lung / Q000382:microbiology / Q000473:pathology; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009976:Orthomyxoviridae Infections / Q000503:physiopathology / Q000628:therapy*; D011134:Polysaccharides / Q000627:therapeutic use*; D014779:Virus Replication / Q000187:drug effects
D000276:Adjuvants, Immunologic; D011134:Polysaccharides; C030207:mytilan
Vliianie mitilana--bioglikana iz midii Crenomytilus grayanus na techenie i iskhod éksperimental'noĭ grippoznoĭ infektsii.