[Immunologic phenotype of malignant lymphoma].
Recent advances in clinical research on surface marker analysis of malignant lymphoma cells are reviewed. Malignant lymphoma can be classified into T-cell malignancy or B-cell malignancy, using flow cytometry or immunohistochemical analysis. Based on recent results of immunophenotypic analysis and clinical data, a new clinicopathologic classification of lymphoid malignancy is proposed. T-cell malignancy bearing T-cell receptor of gamma delta-type is discussed. Other recent topics on malignant lymphoma, such as B-cell lymphoma of the pleural cavity developing from long-standing pyothorax, mediastinal large-B-cell lymphoma with sclerosis, HIV-related B-cell lymphoma, and EB-virus genome carrying B-cell lymphoma in ATL are also discussed.
Tobinai
K
K
Hematology-Oncology and Medical Oncology Division, National Cancer Center Hospital.
Shimoyama
M
M
D000954:Antigens, Surface / Q000032:analysis*; D006801:Humans; D016130:Immunophenotyping; D008223:Lymphoma / Q000145:classification* / Q000276:immunology / Q000473:pathology; D016393:Lymphoma, B-Cell / Q000276:immunology / Q000473:pathology; D016399:Lymphoma, T-Cell / Q000276:immunology / Q000473:pathology; D009367:Neoplasm Staging
D000954:Antigens, Surface