title: A numerical study of the shape of the surface separating flow into branches in microvascular bifurcations.
abstract: The shape of the separating surface formed by the streamlines entering the branches of microvascular bifurcations plays a major role in determining the distribution of red blood cells and other blood constituents downstream from the bifurcation. Using the finite element method, we determined the shape of the surface through numerical solution of three dimensional Navier-Stokes equations for fluid flow at low Reynolds numbers in a T-type bifurcation of circular tubes. Calculations were done for a wide range of daughter branch to parent vessel diameter ratios and flow ratios. The effect of Reynolds number was also studied. Our numerical results are in good agreement with previously reported experimental data of Rong and Carr (Microvascular Research, Vol. 39, pp. 186-202, 1990). The numerical results of this study will be used to predict the concentration of blood constituents downstream from microvascular bifurcations providing that the inlet concentration profile is known.
authors.affiliation: Department of Biomedical Engineering, School of Medicine, Johns Hopkins University, Baltimore, MD 21205.
authors.forename: G
authors.initials: G
authors.lastname: Enden
authors.forename: A S
authors.initials: AS
authors.lastname: Popel
mesh_terms: D001783:Blood Flow Velocity; D001809:Blood Viscosity; D004730:Endothelium, Vascular / Q000033:anatomy & histology*; D005069:Evaluation Studies as Topic; D006439:Hemodynamics; D008433:Mathematics; D008833:Microcirculation / Q000033:anatomy & histology* / Q000502:physiology; D008955:Models, Cardiovascular; D015233:Models, Statistical; D016012:Poisson Distribution; D012212:Rheology; D013499:Surface Properties