title: [Prophylaxis in prostatic surgery with aztreonam. Our experience].
abstract: Aztreonam is a monobactam antibiotic with a very specific spectrum of action for gram-negative aerobic bacteria. Since these bacteria are responsible for most of the urinary tract infections, we conducted a study to determine its efficacy in the prophylaxis and treatment of infections in prostate surgery, one of the most common procedures performed in our field. Thirty-two patients received 1 gm Aztreonam at the time of anesthetic induction and q 8 h thereafter to a total dose of 3 gm. Cultures were performed before and 72 h after surgery. Twenty-eight patients had no complications and a sterile urine culture or less than 10,000 colonies, 2 developed wound infection from Staph, aureus and 1 had more than 100,000 colonies of Enterococci in urine. The foregoing findings indicate that Aztreonam is useful for prophylaxis and treatment of urinary tract infections in prostate surgery.
authors.affiliation: Servicio de Urología, Hospital La Princesa, Universidad Autónoma, Madrid, España.
authors.forename: J L
authors.initials: JL
authors.lastname: Moyano Calvo
authors.forename: R
authors.initials: R
authors.lastname: Arellano Gañán
authors.forename: A
authors.initials: A
authors.lastname: Sempere Gutiérrez
authors.forename: J
authors.initials: J
authors.lastname: Sanz Sacristán
authors.forename: F
authors.initials: F
authors.lastname: Teba del Pino
authors.forename: F J
authors.initials: FJ
authors.lastname: Melón Rey
authors.forename: L
authors.initials: L
authors.lastname: Herrero Torres
authors.forename: I
authors.initials: I
authors.lastname: Pereira Sanz
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001398:Aztreonam / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*; D011292:Premedication; D011469:Prostatic Diseases / Q000601:surgery*; D014552:Urinary Tract Infections / Q000517:prevention & control*
chemical_list: D001398:Aztreonam
vernacular_title: Profilaxis en cirugía prostática con Aztreonam. Nuestra experiencia.