[Presence and significance of anticardiolipin antibodies in infectious diseases].
IgG and IgM anti-cardiolipin antibodies were measured, by an ELISA technique, in the sera of patients with B hepatitis (28), infectious mononucleosis (10), chicken pox (12), HIV infection (20), acquired toxoplasmosis (41) and other infectious diseases [HBsAg+ chronic hepatitis (5), brucellosis (6), herpes zoster (4), boutonneuse fever (3), viral pneumonitis (4), rheumatic fever (2)]. Increased levels of anti-cardiolipin antibodies (aCL), at least in one immunoglobulin class, were detected in 37 out of 135 patients [27.4%; range: 7.3% (in the patients with toxoplasmosis) -80% (in the patients with HIV infection)]. Low or medium titer aCL were present in 28 patients, high titer in 9 (6 with HIV infection, 2 with chicken pox and I with lymphoadenopathic toxoplasmosis). None of the manifestations associated with aCL was present in the aCL-positive patients. Finally, positivity for aCL didn't seem to modify the clinical picture and the prognosis of the infectious disease.
Barrile
A
A
Istituto di Patologia medica e Medicina mediterranea, Università, Messina.
Quattrocchi
P
P
Bonanno
D
D
Crisafi
A
A
Staiti
A
A
Magaraci
G
G
Romano
S
S
Sturniolo
G
G
Ricciardi
R
R
Ferlazzo
B
B
D000293:Adolescent; D000328:Adult; D000906:Antibodies / Q000032:analysis*; D002308:Cardiolipins / Q000276:immunology*; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007239:Infections / Q000276:immunology*; D008297:Male; D008875:Middle Aged
D000906:Antibodies; D002308:Cardiolipins; D007074:Immunoglobulin G; D007075:Immunoglobulin M
Sulla presenza e sul significato degli anticorpi anti-cardiolipina nelle malattie infettive.