title: Chromosomal assignment of human phenol and bilirubin UDP-glucuronosyltransferase genes (UGT1A-subfamily).
abstract: DNA probes were prepared from the 5'-terminal portion of four cDNA clones encoding human phenol and bilirubin UDP-glucuronosyltransferases (UGTs). An additional sequence common to all four clones was isolated from the 3'-terminal portion of one of the clones (UGT1A1). The four specific and the one common DNA sequences were used as probes on a panel of 16 human--rodent somatic cell hybrid DNAs by Southern-blot analysis. The results obtained indicate that all four cDNA clones are encoded by gene(s) located on human chromosome 2.
authors.affiliation: University Department of Biochemical Medicine, Ninewells Hospital and Medical School, Dundee, Scotland.
authors.forename: N
authors.initials: N
authors.lastname: Moghrabi
authors.forename: L
authors.initials: L
authors.lastname: Sutherland
authors.forename: R
authors.initials: R
authors.lastname: Wooster
authors.forename: S
authors.initials: S
authors.lastname: Povey
authors.forename: M
authors.initials: M
authors.lastname: Boxer
authors.forename: B
authors.initials: B
authors.lastname: Burchell
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D002889:Chromosomes, Human, Pair 2; D015342:DNA Probes; D014453:Glucuronosyltransferase / Q000235:genetics*; D006801:Humans; D006822:Hybrid Cells; D051381:Rats
chemical_list: D015342:DNA Probes; D014453:Glucuronosyltransferase