Exuberant epibulbar tumor penetrating into the orbit in xeroderma pigmentosum.
The clinical and histopathological findings are described in a 10-year-old girl with xeroderma pigmentosum and multiple ophthalmic complications, including the eyelids, conjunctiva, orbit, cornea and iris; some of these complications took an unusual form. Histological examination following right orbital exenteration revealed an epibulbar squamous cell carcinoma penetrating the orbit and building a noose all around the ocular globe with subsequent strangulation. Moreover, a palpebral squamous cell carcinoma developed independently from the right lower lid and, unconnected with the epibulbar tumor, penetrated to the orbit.
Calugaru
M
M
Department of Ophthalmology, Medical School, University of Cluj-Napoca, Romania.
Barsu
M
M
D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000556:secondary; D002648:Child; D005142:Eyelid Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D016609:Neoplasms, Second Primary / Q000473:pathology*; D009918:Orbital Neoplasms / Q000473:pathology*; D014983:Xeroderma Pigmentosum / Q000473:pathology*