title: [Typical findings and erroneous findings in SPECT-radioimmunoscintigraphy using 99mTc-labeled CEA antibodies in colorectal tumors].
abstract: Radioimmunoscintigraphy with 99mTc-labelled monoclonal antibodies against Carcino-Embryonic-Antigen (CEA) is increasingly accepted in the follow-up of patients suffering from colorectal carcinomas. However, interpretation of transversal, coronal and sagittal reconstructions of "Single Photon Emission Computed Tomography" radioimmunoscintigraphic studies is difficult due to physiological antibody accumulations and anatomical based variations of antibody distribution. In the following study we demonstrate therefore, the typical findings and "pitfalls" of radioimmunoscintigraphy with 99mTc-labelled CEA antibodies in comparison to findings in computed tomography, to help to avoid misinterpretations.
authors.affiliation: Strahlenklinik und Poliklinik, Klinikum Rudolf Virchow, Freie Universität, Berlin.
authors.forename: G
authors.initials: G
authors.lastname: Barzen
authors.forename: R
authors.initials: R
authors.lastname: Felix
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging*; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging; D016719:Radioimmunodetection; D012004:Rectal Neoplasms / Q000000981:diagnostic imaging*; D013667:Technetium; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D013667:Technetium
vernacular_title: Typische Befunde und Fehlbefunde in der SPECT-Radioimmunszintigrapie mit 99mTc-markierten CEA Antikörpern bei kolorektalen Tumoren.