title: Electroejaculation in combination with in vitro fertilization and gamete micromanipulation for treatment of anejaculatory male infertility.
abstract: OBJECTIVE
  Failure to ejaculate may be overcome by use of electroejaculation. However, such semen samples are often unsuitable for therapies like intrauterine insemination. The combination of electroejaculation with in vitro fertilization, including gamete micromanipulation, should improve chances of fertilization and pregnancy in such cases.
  
  
  METHODS
  Within a private infertility clinic electroejaculation in combination with intrauterine insemination was carried out in 18 cycles (10 couples). Four couples went on to receive therapy by electroejaculation plus in vitro fertilization, along with six other couples (15 cycles total) with semen too poor for intrauterine insemination.
  
  
  RESULTS
  One term pregnancy arose in the electroejaculation-intrauterine insemination group, and one term pregnancy plus one continuing pregnancy arose from two couples (three cycles) who underwent in vitro fertilization with conventional insemination after electroejaculation. Six couples (nine cycles) had embryos arising only from gamete micromanipulation transferred, and this yielded two term pregnancies, one spontaneous abortion, and a biochemical pregnancy. Two couples (three cycles) failed to achieve fertilization even with micromanipulation; however, donor-inseminated eggs gave rise to two term pregnancies and one continuing pregnancy in these patients.
  
  
  CONCLUSIONS
  This report confirms the feasibility of in vitro fertilization in conjunction with electroejaculation and extends the therapy to incorporate gamete micromanipulation.
authors.affiliation: Reproductive Biology Associates, Atlanta, GA 30342.
authors.forename: A A
authors.initials: AA
authors.lastname: Toledo
authors.forename: M J
authors.initials: MJ
authors.lastname: Tucker
authors.forename: J K
authors.initials: JK
authors.lastname: Bennett
authors.forename: B G
authors.initials: BG
authors.lastname: Green
authors.forename: H I
authors.initials: HI
authors.lastname: Kort
authors.forename: S R
authors.initials: SR
authors.lastname: Wiker
authors.forename: G
authors.initials: G
authors.lastname: Wright
mesh_terms: D000328:Adult; D004542:Ejaculation; D004599:Electric Stimulation Therapy; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007248:Infertility, Male / Q000473:pathology / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D011247:Pregnancy; D013076:Sperm Count; D013081:Sperm Motility