title: Neuroleptic malignant syndrome presenting as hyperosmolar non-ketotic diabetic coma.
abstract: A 50-year-old man presented with hyperosmolar non-ketotic diabetic coma associated with the neuroleptic malignant syndrome (NMS) after intramuscular treatment with haloperidol. It is suggested that NMS may occur as a complication of uncontrolled diabetes mellitus with dehydration. Conversely, NMS might precipitate diabetic coma in patients with previously well controlled blood glucose.
authors.affiliation: Department of Medicine, St Luke's Hospital, Malta.
authors.forename: M
authors.initials: M
authors.lastname: Balzan
authors.forename: J M
authors.initials: JM
authors.lastname: Cacciottolo
mesh_terms: D001833:Body Temperature Regulation / Q000187:drug effects; D003131:Combined Modality Therapy; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D004565:Electroconvulsive Therapy; D006220:Haloperidol / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D006944:Hyperglycemic Hyperosmolar Nonketotic Coma / Q000139:chemically induced* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009459:Neuroleptic Malignant Syndrome / Q000175:diagnosis*; D014268:Trifluoperazine / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D014268:Trifluoperazine; D006220:Haloperidol