title: Quantitative and morphological observations on the ultrastructure of articular tissue generated from free periosteal grafts.
abstract: This study investigates the ultrastructure of articular tissue generated on osteochondral defects in skeletally immature rabbits from free reversed periosteal allografts after 50 and 100 days of post-operative intermittent active motion. Tissue samples prepared for transmission electron microscopy were compared with normal cartilage and periosteum in terms of cell morphology and the pattern of intercellular collagen deposition. Well-differentiated tissue demonstrated many ultrastructural features of normal articular cartilage while poorly differentiated samples contained cells and intercellular collagen profiles which were somewhat similar to those observed in periosteum.
authors.affiliation: Department of Surgery, University College, Cork, Ireland.
authors.forename: W A
authors.initials: WA
authors.lastname: Curtin
authors.forename: W J
authors.initials: WJ
authors.lastname: Reville
authors.forename: M P
authors.initials: MP
authors.lastname: Brady
mesh_terms: D000818:Animals; D002358:Cartilage, Articular / Q000737:chemistry / Q000166:cytology / Q000648:ultrastructure*; D002454:Cell Differentiation; D003094:Collagen / Q000032:analysis / Q000648:ultrastructure; D008854:Microscopy, Electron; D010521:Periosteum / Q000166:cytology / Q000637:transplantation* / Q000648:ultrastructure; D011817:Rabbits; D013997:Time Factors; D014184:Transplantation, Homologous
chemical_list: D003094:Collagen