title: Focal nodular hyperplasia of the liver: MR imaging and pathologic correlation in 37 patients.
abstract: Thirty-seven patients with 48 lesions of focal nodular hyperplasia (FNH) underwent preoperative magnetic resonance (MR) examination and surgical resection. Sixteen lesions were imaged at 0.5 T with T1- and T2-weighted spin-echo sequences; 32 lesions were imaged at 2 T with T1-and T2-weighted spin-echo and gradient-recalled-echo sequences. Contrast material-enhanced MR imaging was performed in 20 lesions. MR imaging failed to depict six tumors that were less than 3 cm in diameter. Typical appearance was present in 18 of the 42 (43%) lesions seen at MR. Atypical lesion features included no scar (n = 15), hypointense scar on T2-weighted images (n = 7), pseudocapsule (n = 6), strong hyperintense lesion on T2-weighted images (n = 3), diffuse hyperintensity on T1-weighted images (n = 3), and heterogeneous lesion (n = 1). Comparison between findings at MR imaging and at histopathologic examination was performed in 38 lesions: There was good correlation between presence and size of the scar on both examinations. In 13 of 20 (65%) of the hyperintense scars on T2-weighted images, edema was prominent, whereas in five of the seven (71%) hypointense scars on T2-weighted images, edema was absent or low.
authors.affiliation: Department of Radiology, Hôpital Beaujon, Clichy, France.
authors.forename: V
authors.initials: V
authors.lastname: Vilgrain
authors.forename: J F
authors.initials: JF
authors.lastname: Fléjou
authors.forename: L
authors.initials: L
authors.lastname: Arrivé
authors.forename: J
authors.initials: J
authors.lastname: Belghiti
authors.forename: D
authors.initials: D
authors.lastname: Najmark
authors.forename: Y
authors.initials: Y
authors.lastname: Menu
authors.forename: M
authors.initials: M
authors.lastname: Zins
authors.forename: M P
authors.initials: MP
authors.lastname: Vullierme
authors.forename: H
authors.initials: H
authors.lastname: Nahum
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D006965:Hyperplasia; D008099:Liver / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged