title: Athetoid cerebral palsy with cysts in the putamen after hypoxic-ischaemic encephalopathy.
abstract: Three cases of athetoid cerebral palsy after hypoxic-ischaemic encephalopathy (HIE) are reported. All three neonates had haemorrhagic lesions in the basal ganglia and thalami on magnetic resonance imaging (MRI). Prior cranial ultrasound had detected the lesions in only two cases. In all three children athetoid movements began within the first year of life. Follow up MRI scans showed bilateral symmetrical cystic lesions in the posterior putamen. Although haemorrhagic lesions within the basal ganglia are a common MRI finding in neonates with HIE, few of these babies develop athetoid cerebral palsy. We believe this to be the first report of discrete cystic lesions found in the basal ganglia of children with athetoid cerebral palsy.
authors.affiliation: Department of Paediatrics, Hammersmith Hospital, London.
authors.forename: M A
authors.initials: MA
authors.lastname: Rutherford
authors.forename: J M
authors.initials: JM
authors.lastname: Pennock
authors.forename: D M
authors.initials: DM
authors.lastname: Murdoch-Eaton
authors.forename: F M
authors.initials: FM
authors.lastname: Cowan
authors.forename: L M
authors.initials: LM
authors.lastname: Dubowitz
mesh_terms: D001480:Basal Ganglia Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D002545:Brain Ischemia / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D002547:Cerebral Palsy / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D003560:Cysts / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D004453:Echoencephalography; D005260:Female; D006801:Humans; D002534:Hypoxia, Brain / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D011446:Prospective Studies; D011699:Putamen / Q000000981:diagnostic imaging / Q000473:pathology; D013786:Thalamic Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D014057:Tomography, X-Ray Computed