title: Rate and frequency interactions in the auditory brainstem response of the adult rat.
abstract: Tone pip stimuli were used at different repetition rates to examine influences upon auditory brainstem response components. Rate increases to 80.1/s result in significant latency increases in waves IV and V at all test frequencies. Rate effects occur in rostral brainstem response components which show frequency related latencies different from wave I. Amplitude measures decline at higher repetition rates for waves I and IV at most test frequencies. Rate effects are most pronounced at 8 kHz stimulation which is around the optimal behavioral frequency in rat. At higher rates the second peak of wave I is enhanced at 8 kHz, whereas the third peak of wave I at 40 kHz disappears. These results demonstrate that tone-specific stimuli provide sensitive measures of latency, amplitude and wave morphology of components of the auditory brainstem response as a function of stimulus repetition.
authors.affiliation: Department of Speech-Language Pathology and Audiology, University of South Carolina, Columbia 29208.
authors.forename: E H
authors.initials: EH
authors.lastname: Newton
authors.forename: W A
authors.initials: WA
authors.lastname: Cooper
authors.forename: J R
authors.initials: JR
authors.lastname: Coleman
mesh_terms: D000161:Acoustic Stimulation; D000818:Animals; D004594:Electrophysiology; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains