title: [Determination of partially cellular and local immune function in patients with spleen deficiency syndrome].
abstract: The immune function status as reflected by the peripheral blood OKT system T cell subset classification and the lymphocyte in vitro interleukin 2 (IL2) secretory function were determined in 30 patients with Spleen deficiency syndrome and 20 normal subjects in this study. Experimental results decreased cellular immune function and disturbance of immune regulatory mechanism in the patients. Its manifestations were decreased number of total T lymphocytes and helper T cells (Th), relatively increased suppressor T cells (Ts), abnormal rate of Th to Ts, no marked change of IL2 secretory function of T cell in vitro, increased SIgA level before stimulating with acid but marked decreased SIgA level after stimulating. All these suggest the compensatory stage of local immune function.
authors.affiliation: Tianjin Institute of Acute Abdominal Diseases.
authors.forename: J
authors.initials: J
authors.lastname: Ding
authors.forename: X Z
authors.initials: XZ
authors.lastname: Wu
authors.forename: X P
authors.initials: XP
authors.lastname: Xue
mesh_terms: D000328:Adult; D000368:Aged; D016516:CD4-CD8 Ratio; D002769:Cholelithiasis / Q000276:immunology; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007071:Immunoglobulin A, Secretory / Q000378:metabolism; D007376:Interleukin-2 / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000276:immunology; D012463:Saliva / Q000276:immunology; D013158:Splenic Diseases / Q000276:immunology*; D013577:Syndrome; D016176:T-Lymphocyte Subsets / Q000276:immunology; D016711:Yang Deficiency / Q000276:immunology*
chemical_list: D007071:Immunoglobulin A, Secretory; D007376:Interleukin-2