title: A biometrical genetic approach to chromosome analysis in Drosophila: detection of epistatic interactions in geotaxis.
abstract: Chromosome analysis has been widely used as a first step in elucidating the genetic architecture of several behaviors of Drosophila melanogaster. These chromosome studies have generally used incomplete designs or fairly simple statistical analyses. Here I reanalyze two data sets on geotaxis from Pyle (1978) and Ksander (1966) using a biometrical genetic design. Results from the biometrical genetic reanalysis suggest that individual differences in geotaxis might be due to genes on all three major chromosomes which show extensive epistatic interactions.
authors.affiliation: Department of Biological Sciences, Nelson Biological Laboratories, Rutgers State University of New Jersey, Piscataway 08855-1059.
authors.forename: T R
authors.initials: TR
authors.lastname: McGuire
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D004331:Drosophila melanogaster / Q000235:genetics*; D004843:Epistasis, Genetic; D006580:Genetic Carrier Screening; D006720:Homozygote; D008957:Models, Genetic; D009949:Orientation / Q000502:physiology*; D012641:Selection, Genetic