title: [Clinicopathological and immunohistochemical study of malignant lymphoma of the orbit].
abstract: The authors performed histopathological and immunohistochemical studies of 14 cases of orbital malignant lymphoma except for the conjunctival one. The patients were composed of 9 males and 5 females, and the average age of the cases was 61.5 +/- 12.3 years old. All cases were unilateral malignant lymphomas, 5 cases were right and 9 cases were left. Two patients had stage I disease, 10 patients had stage II disease, and 2 patients had stage III disease. The 5 year-survival rate was in 7/12 (58%). Histopathological examination revealed that 3 cases belonged to small lymphocytic, 4 cases diffuse small cleaved, 3 cases diffuse mixed and 4 cases diffuse large cell type by the working formulation. Immunohistochemical examination showed that all cases reacted positively against the B cell markers, while negatively against the T cell markers except for 1 case, indicating the cases were B cell lymphomas. Additionally, an immunoglobulin study contributed to elucidate the monoclonal proliferation of the tumor cells.
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Sakamoto
authors.forename: T
authors.initials: T
authors.lastname: Ishibashi
authors.forename: Y
authors.initials: Y
authors.lastname: Ohnishi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000175:diagnosis / Q000473:pathology*