title: [Rheumatic features of Grave's disease in children].
abstract: We report three cases from girls with Graves disease who developed serious rheumatic manifestations. One patient had systemic lupus erythematosus with articular, renal, neurological and cardiac afectation with fatal outcome. Other patient presented clinical features of scleroderma with skin thickness, myopathy, arthritis, Raynaud's phenomenon and findings of pulmonary fibrosis. A lupus-like syndrome associated to methimazole therapy (polyarthritis, rash and hemolytic anemia) with positive Cel-LE preparations but negative antinuclear-antibodies was observed in a third patient. A careful history and the recognition of these manifestations will help in the identification of these syndromes.
authors.affiliation: Centro Médico de Occidente, Instituto Mexicano del Seguro Social.
authors.forename: M
authors.initials: M
authors.lastname: Chávez-Legaspi
authors.forename: R
authors.initials: R
authors.lastname: Ocampo-Campos
authors.forename: E
authors.initials: E
authors.lastname: García-Velarde
authors.forename: J
authors.initials: J
authors.lastname: Ríos-González
mesh_terms: D005260:Female; D006111:Graves Disease / Q000150:complications*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000209:etiology; D012216:Rheumatic Diseases / Q000209:etiology*; D012595:Scleroderma, Systemic / Q000209:etiology
vernacular_title: Aspectos reumáticos de la enfermedad de Graves en niños.