title: Serum interleukin (IL-1 beta) in patients with diffuse scleritis.
abstract: Scleritis is a painful, destructive inflammatory eye disease. We measured serum IL-1 beta in ten patients with diffuse scleritis and in control subjects matched for age and sex. Patients with diffuse scleritis were found to have significantly elevated serum concentrations of IL-1 beta in comparison to normal subjects (P less than 0.02). The results suggest that IL-1 beta is associated with diffuse scleritis and may influence scleral breakdown in diffuse scleritis.
authors.affiliation: Department of Ophthalmology, University of the Witwatersrand, Johannesburg, South Africa.
authors.forename: G N
authors.initials: GN
authors.lastname: Palexas
authors.forename: A
authors.initials: A
authors.lastname: Puren
authors.forename: N
authors.initials: N
authors.lastname: Savage
authors.forename: N H
authors.initials: NH
authors.lastname: Welsh
mesh_terms: D000328:Adult; D006801:Humans; D007375:Interleukin-1 / Q000097:blood*; D015423:Scleritis / Q000097:blood*
chemical_list: D007375:Interleukin-1