Evaluation of silicone gel as a long-term vitreous substitute in non-human primates.
Two preparations of silicone gels were evaluated as long-term vitreous substitutes in the vitrectomized and lensectomized eyes of primates. Both preparations were injected in liquid form and polymerized in the vitreous cavity. There was no toxic effect on the ocular structures up to 13 months after implantation. Fundus examination and fluorescein angiography were possible through the less rigid gel, whereas the preparation with higher rigidity consistently appeared cloudy.
Peyman
G A
GA
School of Medicine, LSU Eye Center, New Orleans 70112.
Conway
M D
MD
Karaçorlu
M
M
Soike
K F
KF
Bhatt
N
N
Clark
L C
LC
Hoffmann
R E
RE
D000818:Animals; D002387:Cataract Extraction; D002522:Chlorocebus aethiops; D002924:Ciliary Body / Q000187:drug effects / Q000473:pathology; D004596:Electroretinography; D005069:Evaluation Studies as Topic; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D005782:Gels; D007267:Injections; D007429:Intraocular Pressure; D019736:Prostheses and Implants; D012160:Retina / Q000187:drug effects / Q000473:pathology; D012826:Silicone Elastomers / Q000633:toxicity*; D014821:Vitrectomy; D014822:Vitreous Body
D005782:Gels; D012826:Silicone Elastomers