title: [Anesthesia with high dosage fentanyl in coronary patients: effects of pretreatment with droperidol and diazepam].
abstract: The Authors have considered the effects of droperidol or diazepam treatments in patients undergoing high-dose fentanyl anesthesia in cardiac surgery. Twenty patients have been examined and divided in two groups: group A received droperidol (0.2 mg.kg-1) and group B diazepam (0.1 mg.kg-1) five minutes after fentanyl anesthesia induction (500 micrograms.min-1) to reach the "sleep dose". The diazepam pretreatment, as regards droperidol, reduces a dose of fentanyl necessary to obtain the conscience loss (21.5 +/- 2.5 micrograms.kg-1 vs 28 +/- 2.9 micrograms.kg-1). Hemodynamically the droperidol group is very stable, whereas the diazepam group shows certain myocardial depression and less protection at the OTI time.
authors.affiliation: Istituto di Anestesia e Rianimazione, Università degli Studi di Roma, La Sapienza.
authors.forename: A
authors.initials: A
authors.lastname: Menichetti
authors.forename: L
authors.initials: L
authors.lastname: Tritapepe
authors.forename: R
authors.initials: R
authors.lastname: Favaro
authors.forename: G
authors.initials: G
authors.lastname: Fierro
authors.forename: C
authors.initials: C
authors.lastname: Di Giovanni
authors.forename: M
authors.initials: M
authors.lastname: Pacilli
authors.forename: D
authors.initials: D
authors.lastname: Brancadoro
mesh_terms: D000758:Anesthesia; D003327:Coronary Disease / Q000601:surgery*; D003975:Diazepam; D004329:Droperidol; D005260:Female; D005283:Fentanyl; D006801:Humans; D008297:Male; D008875:Middle Aged; D011229:Preanesthetic Medication
chemical_list: D004329:Droperidol; D003975:Diazepam; D005283:Fentanyl
vernacular_title: Anestesia con fentanyl ad alti dosaggi nel paziente coronarico: effetti di un pretrattamento con droperidolo e diazepam.