title: The TATA-binding protein: a central role in transcription by RNA polymerases I, II and III.
abstract: The TATA-box-binding protein, first noted for its association with the general transcription factor TFIID, has recently been shown to be required for transcription by all three classes of nuclear RNA polymerase found in eukaryotes. As such, it plays a unique and pivotal role in gene expression in higher organisms.
authors.affiliation: Wellcome/CRC Institute, Cambridge, UK.
authors.forename: R J
authors.initials: RJ
authors.lastname: White
authors.forename: S P
authors.initials: SP
authors.lastname: Jackson
mesh_terms: D000818:Animals; D004268:DNA-Binding Proteins / Q000378:metabolism*; D006801:Humans; D012318:RNA Polymerase I / Q000378:metabolism*; D012319:RNA Polymerase II / Q000378:metabolism*; D012320:RNA Polymerase III / Q000378:metabolism*; D016385:TATA Box; D035181:TATA-Box Binding Protein; D014157:Transcription Factors / Q000378:metabolism*; D014158:Transcription, Genetic
chemical_list: D004268:DNA-Binding Proteins; D035181:TATA-Box Binding Protein; D014157:Transcription Factors; D012319:RNA Polymerase II; D012318:RNA Polymerase I; D012320:RNA Polymerase III