title: [An attempt to control nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infection].
abstract: A strain of Methicillin-Resistant Staphylococcus aureus (MRSA) was first isolated in our hospital in March 1986. Since then, MRSA has become a difficult pathogen and a cause of sepsis, bacterial endocarditis, and pneumonia in 1988. Rigorous hospital-wide control measures have been planned. The major control measures, based on the various investigations reported, consist of the following three points; improvement of environmental control, reinforcement of handwashing practices during care and control usage of antibiotics. The frequency of isolation of MRSA among the S. aureus isolates was 43.3% in 1988 and this was further reduced to 31.7% in 1990. The total number of MRSA isolates from decubitus, bile, and blood samples have also declined. This decline resulted in a reduction of cases of severe MRSA infection. As yet, MRSA strain are still isolated on incubation. There may be a limit to complete control by measures in a single hospital. It is desired that regional measures and national consensus on nosocomial infection be established.
authors.affiliation: Department of Pharmacy, Tachikawa Sohgo Hospital.
authors.forename: N
authors.initials: N
authors.lastname: Miyachi
authors.forename: M
authors.initials: M
authors.lastname: Ishikawa
authors.forename: F
authors.initials: F
authors.lastname: Ohishi
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D003428:Cross Infection / Q000382:microbiology / Q000517:prevention & control*; D004203:Disinfection; D004783:Environmental Microbiology; D006235:Hand Disinfection; D006801:Humans; D016106:Methicillin Resistance; D011292:Premedication; D013203:Staphylococcal Infections / Q000382:microbiology / Q000517:prevention & control*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents