title: [Change of the complement level in patients with insulin-dependent diabetes mellitus in the course of intensified insulin therapy].
abstract: Intensified insulin therapy in patients with type I diabetes mellitus is accompanied by a decrease in a total daily dose of insulin and the activity of the first 5 components of the classical pathway and CH50. A decrease in function of the first 5 components of the complement against a background of intensified insulin therapy can serve as a positive prognostic criterion of stabilization of development of diabetic angiopathies.
authors.forename: L V
authors.initials: LV
authors.lastname: Kozlov
authors.forename: V P
authors.initials: VP
authors.lastname: Ageev
authors.forename: M N
authors.initials: MN
authors.lastname: Sizoĭ
authors.forename: N S
authors.initials: NS
authors.lastname: Beskova
authors.forename: I I
authors.initials: II
authors.lastname: Dedov
authors.forename: M Sh
authors.initials: MSh
authors.lastname: Shamkhalova
authors.forename: I A
authors.initials: IA
authors.lastname: Abugova
mesh_terms: D000293:Adolescent; D000328:Adult; D003165:Complement System Proteins / Q000378:metabolism*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000188:drug therapy; D003925:Diabetic Angiopathies / Q000097:blood; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007328:Insulin / Q000627:therapeutic use*; D008297:Male; D011379:Prognosis
chemical_list: D007328:Insulin; D003165:Complement System Proteins
vernacular_title: Izmenenie urovnia komplementa u bol'nykh insulinzavisimym sakharnym diabetom pri intensifitsirovannoĭ insulinoterapii.