title: Hydatidiform mole with coexisting twin pregnancy after gamete intra-fallopian transfer.
abstract: The pregnancy of a 31-year-old infertility patient is described. After gamete intra-Fallopian transfer, her pregnancy evolved uneventfully until the 18th week of gestation, when vaginal bleeding occurred. Ultrasonographic findings suggested a molar pregnancy with two live fetuses. At 24 weeks gestation, two male infants were spontaneously delivered. Fetal (46 XY) and molar (46 XX) karyotypes and post-mortem findings were consistent with a bizygotic twin pregnancy associated with a complete hydatidiform mole. The pathogenesis and obstetrical management are discussed.
authors.affiliation: Department of Obstetrics and Gynaecology, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
authors.forename: E J
authors.initials: EJ
authors.lastname: van de Geijn
authors.forename: C A
authors.initials: CA
authors.lastname: Yedema
authors.forename: D J
authors.initials: DJ
authors.lastname: Hemrika
authors.forename: M F
authors.initials: MF
authors.lastname: Schutte
authors.forename: J J
authors.initials: JJ
authors.lastname: ten Velden
mesh_terms: D000328:Adult; D000658:Amoxicillin / Q000627:therapeutic use; D005260:Female; D015181:Gamete Intrafallopian Transfer / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D006828:Hydatidiform Mole / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D007752:Obstetric Labor, Premature / Q000188:drug therapy; D010920:Placenta / Q000473:pathology; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D011272:Pregnancy, Multiple; D012312:Ritodrine / Q000627:therapeutic use; D014427:Twins; D014463:Ultrasonography; D014591:Uterine Diseases / Q000188:drug therapy; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology
chemical_list: D008795:Metronidazole; D000658:Amoxicillin; D012312:Ritodrine