title: [Mucocutaneous lichen planus with esophageal involvement. A clinical case].
abstract: The paper reports the case of a 58-year-old woman suffering from mucosal and cutaneous lichen planus (LP) with esophageal and oral involvement, who had complained of dysphagia for approximately the past two years. The diagnosis of esophageal LP was made using esophagoscopy with mucosal biopsy. The differential diagnosis between LP and progressive systemic sclerosis is discussed; a cold-test, plethysmography of the limbs, an anti-ENA Sci-70 antibody assay, X-rays of soft tissues and esophagomanometry were performed for this purpose, and all proved normal. The presence of conditions implicated in the etiopathogenesis of LP (psychic disorders and the administration of psychoactive drugs, anti-hypertensives and FANS) were observed, together with an already known association with arterial hypertension. Altered hepatic function (with an increase in cholestasis enzymes) was also noted which is probably attributable to the prolonged use of psychoactive drugs (hepatic biopsy showed severe steatosis).
authors.affiliation: Istituto di Clinica Medica Generale, Università Cattolica del Sacro Cuore, Roma.
authors.forename: D
authors.initials: D
authors.lastname: Schiavino
authors.forename: F
authors.initials: F
authors.lastname: Murzilli
authors.forename: G
authors.initials: G
authors.lastname: Forti
authors.forename: C
authors.initials: C
authors.lastname: Chiarelli
authors.forename: L
authors.initials: L
authors.lastname: Altomonte
authors.forename: M
authors.initials: M
authors.lastname: Magarò
mesh_terms: D000959:Antihypertensive Agents / Q000009:adverse effects; D003680:Deglutition Disorders / Q000188:drug therapy / Q000209:etiology; D003937:Diagnosis, Differential; D004935:Esophageal Diseases / Q000139:chemically induced / Q000175:diagnosis / Q000188:drug therapy; D004945:Esophagoscopy; D005260:Female; D006801:Humans; D008010:Lichen Planus / Q000139:chemically induced / Q000175:diagnosis / Q000188:drug therapy; D008875:Middle Aged; D009543:Nifedipine / Q000627:therapeutic use; D011619:Psychotropic Drugs / Q000009:adverse effects; D012595:Scleroderma, Systemic / Q000175:diagnosis; D014801:Vitamin A / Q000627:therapeutic use
chemical_list: D000959:Antihypertensive Agents; D011619:Psychotropic Drugs; D014801:Vitamin A; D009543:Nifedipine
vernacular_title: Lichen planus muco-cutaneo con coinvolgimento esofageo. Un caso clinico.