An investigation, by questionnaire, of cases of recalcitrant vaginal trichomoniasis seen in genitourinary medicine clinics in the United Kingdom. British Co-operative Clinical Group.
A total of 24 cases of recalcitrant trichomoniasis were reported from 18 centres widely scattered throughout the UK. Most cases had received numerous courses of unsuccessful treatment. Nine (75%) of 12 tested isolates had a decreased susceptibility to metronidazole. Local laboratories were often unable to evaluate fully trichomonal isolates and it is recommended that consideration be given to the establishment of a national reference laboratory. Although there were no universal cures, successful alternatives to conventional treatments are detailed.
D000554:Ambulatory Care Facilities; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002985:Clinical Protocols / Q000592:standards; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D008795:Metronidazole / Q000008:administration & dosage / Q000627:therapeutic use; D012008:Recurrence; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014247:Trichomonas Vaginitis / Q000097:blood / Q000188:drug therapy / Q000453:epidemiology*; D006113:United Kingdom / Q000453:epidemiology; D015032:Zinc / Q000097:blood
D000900:Anti-Bacterial Agents; D008795:Metronidazole; D015032:Zinc