Risk of malignancy in Sotos syndrome.
A questionnaire survey identified a possibly increased risk of malignancy for patients with Sotos syndrome. Because the sites and types of neoplasm found in these patients vary, no routine screening except for periodic clinical evaluation seems feasible.
Hersh
J H
JH
Child Evaluation Center, University of Louisville, Kentucky.
Cole
T R
TR
Bloom
A S
AS
Bertolone
S J
SJ
Hughes
H E
HE
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005147:Facial Bones / Q000002:abnormalities*; D005260:Female; D006130:Growth Disorders / Q000150:complications* / Q000235:genetics; D006306:Health Surveys; D006801:Humans; D007223:Infant; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000209:etiology*; D012886:Skull / Q000002:abnormalities*; D011795:Surveys and Questionnaires; D013577:Syndrome