title: [Usefulness of dopamine administration after transcatheter hepatic arterial embolization based upon portal hemodynamics].
abstract: We evaluated usefulness of dopamine administration after transcatheter hepatic arterial embolization (TAE) for the prevention of hepatic failure in experimental and clinical study. In experimental study we measured portal blood flow in dogs with doppler catheter before and after TAE. Administration of dopamine after TAE increased portal blood flow significantly. In a clinical study the usefulness of dopamine was investigated in a clinical laboratory test. It revealed that serum GOT and GPT improved earlier with dopamine administration after TAE. In conclusion dopamine increased portal blood flow and decreased hepatic parenchymal damage after TAE.
authors.affiliation: Department of Radiology, Tottori University, School of Medicine.
authors.forename: T
authors.initials: T
authors.lastname: Iwamiya
authors.forename: S
authors.initials: S
authors.lastname: Sawada
authors.forename: Y
authors.initials: Y
authors.lastname: Fujiwara
authors.forename: T
authors.initials: T
authors.lastname: Koyama
authors.forename: N
authors.initials: N
authors.lastname: Tanigawa
authors.forename: M
authors.initials: M
authors.lastname: Kobayashi
authors.forename: T
authors.initials: T
authors.lastname: Ishii
authors.forename: T
authors.initials: T
authors.lastname: Senda
authors.forename: T
authors.initials: T
authors.lastname: Kato
authors.forename: M
authors.initials: M
authors.lastname: Kanba
mesh_terms: D000818:Animals; D004285:Dogs; D004298:Dopamine / Q000627:therapeutic use*; D004621:Embolization, Therapeutic / Q000009:adverse effects*; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D006499:Hepatic Artery; D006801:Humans; D008107:Liver Diseases / Q000209:etiology / Q000517:prevention & control*; D011168:Portal System / Q000187:drug effects* / Q000503:physiopathology
chemical_list: D004298:Dopamine