Body space measurements in the hyponatraemia of carcinoma of the bronchus: evidence for the chronic 'sick cell' syndrome?
Body space measurements using simultaneous multiple isotope dilution techniques were made in both hyponatraemic and normonatraemic patients with carcinoma of the bronchus and wasting, and compared with those in a group of normal volunteers. Both groups of patients showed osmolal loss from cells. The significance of these findings in relation to the development of hyponatraemia is discussed.
Southgate
H J
HJ
Department of Chemical Pathology, Worthing Hospital, UK.
Burke
B J
BJ
Walters
G
G
D000328:Adult; D000368:Aged; D001834:Body Water / Q000378:metabolism; D002283:Carcinoma, Bronchogenic / Q000097:blood*; D005110:Extracellular Space / Q000378:metabolism*; D006801:Humans; D007010:Hyponatremia / Q000097:blood*; D007177:Inappropriate ADH Syndrome / Q000378:metabolism; D008175:Lung Neoplasms / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000097:blood; D012964:Sodium / Q000378:metabolism; D015431:Weight Loss
D012964:Sodium; D011188:Potassium