title: Biphasic constriction of rabbit basilar artery following experimental subarachnoid hemorrhage: a morphometric study.
abstract: To assess the changes in arterial structure resulting from subarachnoid hemorrhage, morphometric analysis was performed on basilar arteries from rabbits that had received an experimental subarachnoid hemorrhage up to 6 days earlier. For morphometric determination, the cross-sectional area of the media, the area of the lumen, and the length of the internal elastic lamina were measured planimetrically. The morphometric diameter of the lumen, the media-to-radius ratio, and several other morphometric parameters were also calculated. Subarachnoid hemorrhage induced significant biphasic constriction of the basilar artery without any changes in the cross-sectional area of the media. The relative amount of smooth muscle cell decreased significantly in the late stage of hemorrhage.
authors.affiliation: Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville 22908.
authors.forename: H
authors.initials: H
authors.lastname: Johshita
authors.forename: N F
authors.initials: NF
authors.lastname: Kassell
authors.forename: T
authors.initials: T
authors.lastname: Sasaki
authors.forename: T
authors.initials: T
authors.lastname: Nakagomi
authors.forename: H
authors.initials: H
authors.lastname: Ogawa
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D001488:Basilar Artery / Q000473:pathology*; D003251:Constriction, Pathologic / Q000209:etiology; D008297:Male; D011817:Rabbits; D013345:Subarachnoid Hemorrhage / Q000150:complications* / Q000473:pathology