Telomeric association of chromosomes in human meningiomas.
In six cases of meningiomas, a karyotype with monosomy 22 and telomeric associations has been observed. The histopathological and cytogenetic correlations showed that the tumors with these chromosomal abnormalities were of a fibroblastic type and presented a certain degree of anaplasia. The relationship between telomeric association and malignancy is discussed.
Vagner-Capodano
A M
AM
Laboratoire de Cytogénétique Oncologique, CHU Timone, Marseille, France.
Grisoli
F
F
Gambarelli
D
D
Figarella
D
D
Pellissier
J F
JF
D002877:Chromosomes, Human; D002892:Chromosomes, Human, Pair 22; D006801:Humans; D007621:Karyotyping; D008577:Meningeal Neoplasms / Q000235:genetics* / Q000473:pathology; D008579:Meningioma / Q000235:genetics* / Q000473:pathology; D009006:Monosomy; D016615:Telomere / Q000502:physiology*