Assignment of the human renal dipeptidase gene (DPEP1) to band q24 of chromosome 16.
Renal dipeptidase (DPEP1) or dehydropeptidase-I (E.C.3.4.13.11) is a kidney membrane enzyme which hydrolyzes a variety of dipeptides. DPEP1 is implicated in the renal metabolism of glutathione and its conjugates and is also responsible for hydrolysis of beta-lactam antibiotics. Using a human DPEP1 cDNA probe, we mapped the human renal dipeptidase gene to human chromosome 16 at band q24 by in situ hybridization.
Nakagawa
H
H
Third Department of Medicine, Kyoto Prefectural University of Medicine, Japan.
Inazawa
J
J
Inoue
K
K
Misawa
S
S
Kashima
K
K
Adachi
H
H
Nakazato
H
H
Abe
T
T
D002871:Chromosome Banding; D002874:Chromosome Mapping; D002885:Chromosomes, Human, Pair 16; D015342:DNA Probes; D004150:Dipeptidases / Q000235:genetics*; D005260:Female; D058851:GPI-Linked Proteins; D006801:Humans; D007668:Kidney / Q000201:enzymology*
D015342:DNA Probes; D058851:GPI-Linked Proteins; D004150:Dipeptidases; C038937:dipeptidase; C549872:dipeptidase 1