Reduced risk of hip fracture in the mothers of patients with osteoarthritis of the hip.
In a population-based study we identified a cohort of 282 women, whose children had been treated for osteoarthritis of the hip. The incidence of hip fracture in these mothers was 0.54 (95% CI 0.35 to 0.83) of that in the whole population of their age and sex. This finding could be explained by a genetic factor for increased rigidity of subchondral bone, making osteoarthritis more likely and osteoporosis less likely.
Aström
J
J
Department of Orthopaedics, Sundsvall Hospital, Sweden.
Beertema
J
J
D000367:Age Factors; D005260:Female; D006620:Hip Fractures / Q000453:epidemiology* / Q000235:genetics; D006801:Humans; D015994:Incidence; D015207:Osteoarthritis, Hip / Q000453:epidemiology* / Q000235:genetics; D012307:Risk Factors; D013548:Sweden / Q000453:epidemiology