Improvement of parkinsonian features correlate with high plasma levodopa values after broad bean (Vicia faba) consumption.
Five healthy volunteers and six patients with Parkinson's disease (PD) ate 250 g cooked broad beans after 12 hours without treatment. During the next four hours a substantial clinical improvement was noted, three patients showed severe dyskinesias, and plasma levodopa concentrations rose.
Rabey
J M
JM
Department of Neurology, Tel Aviv Elias Sourasky Medical Center, Israel.
Vered
Y
Y
Shabtai
H
H
Graff
E
E
Korczyn
A D
AD
D000368:Aged; D001971:Bromocriptine / Q000008:administration & dosage; D002230:Carbidopa / Q000008:administration & dosage; D003131:Combined Modality Therapy; D007887:Fabaceae / Q000737:chemistry; D005260:Female; D006801:Humans; D007980:Levodopa / Q000493:pharmacokinetics*; D008090:Lisuride / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination / Q000187:drug effects; D010300:Parkinson Disease / Q000097:blood / Q000178:diet therapy*; D010946:Plants, Medicinal
D001971:Bromocriptine; D007980:Levodopa; D008090:Lisuride; D002230:Carbidopa