Prophylactic digitalisation in pulmonary surgery.
BACKGROUND
Prophylactic digoxin is widely used in patients undergoing pulmonary surgery to prevent or control cardiac arrhythmias, but whether it is helpful or not is uncertain.


METHODS
An open, controlled randomised prospective clinical study of 111 patients was undertaken to compare the incidence of cardiac arrhythmias in the 58 patients who received preoperative digoxin and the 53 who did not.


RESULTS
Cardiac arrhythmia occurred in half (29/58) of those given prophylactic digoxin and in 36% (19/53) of those who were not. The overall incidence of arrhythmia was 43%, with no statistically significant difference between the groups.


CONCLUSIONS
Cardiac arrhythmias remain an important complication of pulmonary surgery and the incidence is not reduced by prophylactic digoxin.
Ritchie
A J
AJ
Department of Cardiothoracic Surgery, Royal Victoria Hospital, Belfast.
Danton
M
M
Gibbons
J R
JR
D000368:Aged; D001145:Arrhythmias, Cardiac / Q000453:epidemiology / Q000517:prevention & control*; D004077:Digoxin / Q000627:therapeutic use*; D006801:Humans; D015994:Incidence; D007431:Intraoperative Complications / Q000453:epidemiology / Q000517:prevention & control*; D008168:Lung / Q000601:surgery*; D008875:Middle Aged; D011184:Postoperative Period; D011446:Prospective Studies
D004077:Digoxin