Hereditary protein S deficiency presenting with cerebral sinus thrombosis in an adolescent girl.
A 14-year-old girl, on oral contraceptives for 3 months, presented with cerebral sinus thrombosis. Investigation revealed underlying hereditary protein S deficiency. This uncommon cause of cerebral sinus thrombosis and the possible association with oral contraceptives are discussed.
Koelman
J H
JH
Department of Neurology, Academic Medical Centre, Amsterdam, The Netherlands.
Bakker
C M
CM
Plandsoen
W C
WC
Peeters
F L
FL
Barth
P G
PG
D000293:Adolescent; D003276:Contraceptives, Oral / Q000009:adverse effects*; D005260:Female; D006023:Glycoproteins / Q000172:deficiency* / Q000235:genetics; D006801:Humans; D008297:Male; D010375:Pedigree; D017293:Protein S; D012851:Sinus Thrombosis, Intracranial / Q000139:chemically induced / Q000209:etiology* / Q000235:genetics
D003276:Contraceptives, Oral; D006023:Glycoproteins; D017293:Protein S