Gamete intrafallopian transfer in women who had ectopic pregnancy previously.
Eighty-seven women who had previously had ectopic pregnancy underwent 111 gamete intrafallopian transfers (GIFT). Forty-one women had moderate or severe pelvic adhesions, eight had mild pelvic adhesions, and 18 had had the fallopian tubes surgically repaired. The remaining 20 women had no obvious pelvic abnormality except for the absence of one fallopian tube. After stimulation of superovulation, between two and 22 oocytes were retrieved and two to four were transferred into the fallopian tubes after careful assessment of their condition. Twenty-eight pregnancies were achieved (25.2% per cycle), with 23 live births (20.7% per cycle), four abortions (14.3% of all pregnancies), and one ectopic pregnancy (3.6% of all pregnancies, 0.9% per cycle). This experience shows that GIFT can safely produce a reasonable pregnancy rate in carefully selected women who have had ectopic pregnancy.
Guirgis
R R
RR
London Fertility Centre, England.
Craft
I L
IL
D000328:Adult; D005260:Female; D015181:Gamete Intrafallopian Transfer; D006801:Humans; D015994:Incidence; D007247:Infertility, Female / Q000628:therapy*; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000453:epidemiology*; D012008:Recurrence; D012307:Risk Factors