Nonimmune hydrops fetalis and fetal congenital syphilis. A case report.
Nonimmune hydrops fetalis occurred secondary to a syphilitic infection. Ultrasonographic evaluation and cordocentesis were used to confirm the antenatal infection. An IgM antibody specific for Treponema pallidum wall antigen (anti-47-kDa) was used to document the fetal infection. High-dose intravenous penicillin was administered in an attempt to achieve adequate fetal levels.
Hallak
M
M
Department of Obstetrics and Gynecology, Pennsylvania Hospital, Philadelphia.
Peipert
J F
JF
Ludomirsky
A
A
Byers
J
J
D000293:Adolescent; D005260:Female; D006801:Humans; D015160:Hydrops Fetalis / Q000175:diagnosis* / Q000209:etiology; D010400:Penicillin G / Q000627:therapeutic use; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000188:drug therapy; D013590:Syphilis, Congenital / Q000175:diagnosis* / Q000188:drug therapy
D010400:Penicillin G