title: Application of models to determination of nutrient requirements: experimental techniques employing tracers.
abstract: This paper concerns some issues involved in the design of tracer experiments for the development of whole-body compartmental models of nutrient metabolism. It focuses on tracer administration protocol, use of multiple tracers, sampling strategy, measurement types and experiment duration in a pragmatic approach to obtaining data suitable for analysis and interpretation with use of models.
authors.affiliation: Department of Clinical Studies, University of Pennsylvania School of Veterinary Medicine, Kennett Square 19348.
authors.forename: C F
authors.initials: CF
authors.lastname: Ramberg
authors.forename: C R
authors.initials: CR
authors.lastname: Krishnamurti
authors.forename: D
authors.initials: D
authors.lastname: Peter
authors.forename: J E
authors.initials: JE
authors.lastname: Wolff
authors.forename: R C
authors.initials: RC
authors.lastname: Boston
mesh_terms: D000818:Animals; D006801:Humans; D007554:Isotopes; D007700:Kinetics; D008433:Mathematics; D008954:Models, Biological; D009751:Nutritional Requirements
chemical_list: D007554:Isotopes