The 1-h 50-g glucose challenge does not predict large-for-gestational-age infants.
The relationship between the 1-h 50-g glucose challenge performed at 24-28 weeks and subsequent birth of a large-for-gestational-age infant was examined in a cohort of 368 Europid women who had no pre-existing medical condition and experienced no pregnancy complications. The results established that the 1-h 50-g glucose challenge blood glucose level had no predictive power with respect to the birth of a large-for-gestational-age infant. However, the 1-h blood glucose value was found to be significantly related to maternal height, weight and age, indicating that its level also represents processes unconnected to glucose intolerance. The study findings also re-confirmed the importance of parity, height, sex, and weight as determinants of large-for-gestational-age infants.
Phillipou
G
G
Endocrine and Diabetes Laboratory, Queen Elizabeth Hospital, Woodville, South Australia.
D001724:Birth Weight; D001786:Blood Glucose / Q000378:metabolism; D015331:Cohort Studies; D016640:Diabetes, Gestational / Q000097:blood / Q000503:physiopathology*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D016017:Odds Ratio; D011247:Pregnancy; D011256:Pregnancy Outcome; D011262:Pregnancy Trimester, Second; D012044:Regression Analysis; D012307:Risk Factors
D001786:Blood Glucose