[Apolipoprotein AI levels in cord blood].
Lipid is known to increase during pregnancy but the factors responsible for the change have not been established. In addition, the lipid concentration in preeclamptic pregnancy is significantly higher than in normal pregnancy. The apolipoproteins are an important determinant of metabolism and the structure of plasma lipoproteins. The 26 healthy pregnant women, the levels of cord apolipoprotein AI were determined by TIA methods. The cord and plasma apolipoprotein AI were 76.12 +/- 20.04 mg/dl (n = 26, mean +/- S.D.) and 190.50 +/- 18.84 mg/dl, respectively. Cord apolipoprotein levels correlated to maternal age (r = -0.12, p less than 0.05), maternal weight (r = -0.11, p less than 0.01), the gestational week (r = +0.42, p less than 0.01), infant weight (r = -0.01, p less than 0.05), placental weight (r = -0.03, p less than 0.05), and diastotlic blood pressure (r = +0.06, p less than 0.05). These data suggest that the measurement of cord apolipoprotein AI may be a useful factor in evaluating preeclamptic pregnancy.
Kobayashi
S
S
First Department of Obstetrics and Gynecology, Toho University School of Medicine, Tokyo.
Tanaka
M
M
Masaki
K
K
Hirakawa
S
S
Momose
K
K
D000328:Adult; D016632:Apolipoprotein A-I / Q000032:analysis*; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D006801:Humans; D008055:Lipids / Q000097:blood; D011225:Pre-Eclampsia / Q000175:diagnosis / Q000209:etiology / Q000378:metabolism; D011247:Pregnancy / Q000097:blood*
D016632:Apolipoprotein A-I; D008055:Lipids