title: Comparison of fluorescent polarization immunoassay and radioimmunoassay in measuring cortisol levels in prepubertal depressed children.
abstract: Cortisol levels of 21 hospitalized prepubertal depressed children given the dexamethasone suppression test (DST) were measured by radioimmunoassay and by fluorescent polarization immunoassay, a new assay method. Correlation analyses demonstrated a highly significant linear relationship between the two methods of measuring cortisol. Thus, it may be possible to use fluorescent polarization immunoassay to measure cortisol levels in children undergoing the DST.
authors.affiliation: Department of Psychiatry, Ohio State University College of Medicine, Columbus 43210.
authors.forename: R A
authors.initials: RA
authors.lastname: Weller
authors.forename: S
authors.initials: S
authors.lastname: Yaylayan
authors.forename: E B
authors.initials: EB
authors.lastname: Weller
authors.forename: M A
authors.initials: MA
authors.lastname: Fristad
mesh_terms: D000367:Age Factors; D002648:Child; D003866:Depressive Disorder / Q000097:blood* / Q000175:diagnosis; D003907:Dexamethasone; D005260:Female; D016231:Fluorescence Polarization Immunoassay; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D011863:Radioimmunoassay
chemical_list: D003907:Dexamethasone; D006854:Hydrocortisone