title: Development and selection of gamma delta T cells.
abstract: The gamma delta T-cell population, a subpopulation of T cells formed through cell lineages that are independent of the alpha beta T-cell lineage, consists of multiple subsets with distinct receptor repertoires and homing properties. While the cell sublineage is a critical factor in the determination of homing specificity, both cell sublineage and receptor-dependent selection are instrumental in the determination of the functional repertoire.
authors.affiliation: Hoffman-LaRoche Inc., Nutley, New Jersey.
authors.forename: W
authors.initials: W
authors.lastname: Haas
authors.forename: S
authors.initials: S
authors.lastname: Tonegawa
mesh_terms: D000818:Animals; D006801:Humans; D016130:Immunophenotyping; D016693:Receptors, Antigen, T-Cell, alpha-beta / Q000276:immunology; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000235:genetics / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology; D013601:T-Lymphocytes / Q000166:cytology / Q000276:immunology*; D013950:Thymus Gland / Q000276:immunology
chemical_list: D016693:Receptors, Antigen, T-Cell, alpha-beta; D016692:Receptors, Antigen, T-Cell, gamma-delta