The 6p21 chromosome region is nonrandomly involved in endometrial polyps.
An inverted chromosome 6, at bands p21 and q22, has been found as the sole chromosome abnormality in an endometrial polyp from a 50-year-old woman. Since two out of three previously reported endometrial polyps showed a rearrangement of the same band 6p21, the nonrandom involvement of the terminal region of the short arm of chromosome 6 in this benign tumor can be supported.
Dal Cin
P
P
Center for Human Genetics, University of Leuven, Belgium.
De Wolf
F
F
Klerckx
P
P
Van Den Berghe
H
H
D007446:Chromosome Inversion; D002896:Chromosomes, Human, Pair 6; D005260:Female; D006801:Humans; D007621:Karyotyping; D008875:Middle Aged; D011127:Polyps / Q000235:genetics*; D014591:Uterine Diseases / Q000235:genetics*