title: Long-term results of Nissen fundoplication in reflux esophagitis without strictures. Clinical, endoscopic, and pH-metric evaluation.
abstract: The present paper evaluates the efficiency of Nissen fundoplication as an antireflux technique in a series of 51 patients with different grades of esophagitis. Follow-up time averaged 6.6 years. The evaluation includes a clinical assessment, endoscopic study, and 24-hr pH monitoring. The results reveal an acceptable rate of recurrences, with clinical (9.8%) being less frequent than endoscopic (13.7%) or pH-metric (19.6%) recurrences. Side effects appeared in 37.3% of the patients (mainly inability to belch or vomit, and postprandial fullness), which were mild and transitory in most cases. Nissen fundoplication proved effective in controlling long-term gastroesophageal reflux, as over 80% of the patients presented an excellent-to-good clinical situation, without or with minimal digestive consequences.
authors.affiliation: Department of Surgery, University Hospital Virgen de la Arrixaca, Murcia, Spain.
authors.forename: L F
authors.initials: LF
authors.lastname: Martinez de Haro
authors.forename: A
authors.initials: A
authors.lastname: Ortiz
authors.forename: P
authors.initials: P
authors.lastname: Parrilla
authors.forename: J A
authors.initials: JA
authors.lastname: Garcia Marcilla
authors.forename: J L
authors.initials: JL
authors.lastname: Aguayo
authors.forename: G
authors.initials: G
authors.lastname: Morales
mesh_terms: D000328:Adult; D000368:Aged; D004942:Esophagitis, Peptic / Q000503:physiopathology / Q000601:surgery*; D004945:Esophagoscopy; D005260:Female; D005500:Follow-Up Studies; D005748:Gastric Fundus / Q000601:surgery*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D011183:Postoperative Complications; D012008:Recurrence; D016896:Treatment Outcome