[Bioavailability of orally administered iron. Effects of alginate/antacid administration].
Sideropenia is often encountered in medical practice; the iron preparation that presents the highest bioavailability is unquestionably iron sulphate. This compound, however, frequently provokes numerous side-effects that induce the patient to suspend treatment. Here it is shown that the bioavailability of the drug is not changed after intake of alginic acid, while side-effects are considerably reduced.
Campo
S
S
Divisione di Medicina, Ospedale S. Giovanni Calibita, Fatebenefratelli, Isola Tiberina, Roma.
Breda
E
E
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D000464:Alginates / Q000494:pharmacology*; D000536:Aluminum Hydroxide / Q000494:pharmacology; D000747:Anemia, Hypochromic / Q000097:blood / Q000188:drug therapy*; D000863:Antacids / Q000494:pharmacology*; D001639:Bicarbonates / Q000494:pharmacology; D001682:Biological Availability; D004338:Drug Combinations; D005260:Female; D005296:Ferrous Compounds / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics; D006801:Humans; D007501:Iron / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics*; D008297:Male; D008875:Middle Aged; D012824:Silicic Acid / Q000494:pharmacology; D017693:Sodium Bicarbonate
D000464:Alginates; D000863:Antacids; D001639:Bicarbonates; D004338:Drug Combinations; D005296:Ferrous Compounds; D012824:Silicic Acid; D000536:Aluminum Hydroxide; C007829:alginate, aluminium hydroxide, magnesium trisilicate, sodium bicarbonate drug combination; D017693:Sodium Bicarbonate; D007501:Iron
Biodisponibilità di ferro per via orale. Effetti della somministrazione da alginato/antiacidi.