An open clinical pilot study of the efficacy and safety of oral terbinafine in dry non-inflammatory tinea capitis.
Ten patients with dry non-inflammatory tinea capitis were evaluated in a pilot study which ran from September 1989 to February 1990. Each patient was given oral terbinafine for 6 weeks; each was followed up 2 weeks later. Eight (80%) were completely cured, one (10%) was mycologically cured and showed minimal signs and symptoms, and another (10%) showed improvement (negative mycology, but persistent clinical signs and symptoms). No topical or systemic side-effects were noted. Terbinafine appears to be an effective and safe antifungal agent in the treatment of non-inflammatory tinea capitis.
Haroon
T S
TS
Department of Dermatology, King Edward Medical College/Mayo Hospital, Lahore, Pakistan.
Hussain
I
I
Mahmood
A
A
Nagi
A H
AH
Ahmad
I
I
Zahid
M
M
D000293:Adolescent; D000935:Antifungal Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009281:Naphthalenes / Q000627:therapeutic use*; D010865:Pilot Projects; D000077291:Terbinafine; D014006:Tinea Capitis / Q000188:drug therapy*
D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine