title: Comparison between high-field-strength MR imaging and CT for screening of hepatic metastases: a receiver operating characteristic analysis.
abstract: The diagnostic performance of high-field-strength magnetic resonance (MR) imaging (1.5 T) for detection of liver metastases was compared with that of computed tomography (CT). All patients (n = 52) underwent preoperative screening for metastases by means of MR imaging with T1-weighted, proton-density-weighted, and T2-weighted pulse sequences and CT scanning with unenhanced, incremental dynamic bolus-enhanced, and delayed contrast medium-enhanced techniques. Diagnostic performance was evaluated by means of receiver operating characteristic analysis in which 800 images (400 with and 400 without lesions) and five readers (4,000 observations) were used; images were obtained from patients (n = 39) in whom the same anatomic levels were available for all MR imaging and CT studies. Direct comparison between the best MR imaging technique (T2-weighted spin-echo imaging [repetition time, 2,000 msec; echo time, 70 msec]) and the best CT technique (incremental dynamic bolus CT) showed a strong trend of superiority of T2-weighted MR imaging over incremental dynamic bolus CT. No highly statistically significant difference (P greater than or equal to .01), however, was found between these two techniques.
authors.affiliation: Department of Radiology, Westfaelische Wilhelms-University, Muenster, Germany.
authors.forename: E J
authors.initials: EJ
authors.lastname: Rummeny
authors.forename: K
authors.initials: K
authors.lastname: Wernecke
authors.forename: S
authors.initials: S
authors.lastname: Saini
authors.forename: P
authors.initials: P
authors.lastname: Vassallo
authors.forename: W
authors.initials: W
authors.lastname: Wiesmann
authors.forename: J W
authors.initials: JW
authors.lastname: Oestmann
authors.forename: D
authors.initials: D
authors.lastname: Kivelitz
authors.forename: B
authors.initials: B
authors.lastname: Reers
authors.forename: M F
authors.initials: MF
authors.lastname: Reiser
authors.forename: P E
authors.initials: PE
authors.lastname: Peters
mesh_terms: D004938:Esophageal Neoplasms / Q000473:pathology; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000556:secondary*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000473:pathology; D012372:ROC Curve; D014057:Tomography, X-Ray Computed