title: [Growth velocity in thalassemic children receiving different protocols of chelating therapy].
abstract: The aim of this study was to compare growth velocity in thalassemic children using two different treatment protocols. Thalassemic children were initially treated with high daily doses of desferrioxamine, obtaining a good rate of initial growth which then unexpectedly slowed down later. The introduction of a new treatment protocol reducing both the dose and frequency with which the drug was administered provoked a significant increase in the rate of growth greater than that observed in the group treated using the previous protocol.
authors.affiliation: Centro di Auxopatologia Infantile, Università di Torino.
authors.forename: M G
authors.initials: MG
authors.lastname: Elena
authors.forename: A
authors.initials: A
authors.lastname: Fedele
authors.forename: P
authors.initials: P
authors.lastname: Gianino
authors.forename: S
authors.initials: S
authors.lastname: Giordanino
authors.forename: P
authors.initials: P
authors.lastname: Murru
authors.forename: C
authors.initials: C
authors.lastname: Tosi
authors.forename: S
authors.initials: S
authors.lastname: Vannelli
mesh_terms: D015913:Chelation Therapy; D002648:Child; D002675:Child, Preschool; D003676:Deferoxamine / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D006128:Growth / Q000187:drug effects*; D006801:Humans; D008297:Male; D013789:Thalassemia / Q000503:physiopathology* / Q000628:therapy*
chemical_list: D003676:Deferoxamine
vernacular_title: Velocità di crescita dei bambini talassemici sottoposti a diversi protocolli di terapia chelante.