The polymerase chain reaction and cancer diagnostics.
In this review, I describe the polymerase chain reaction (PCR) and its application to cancer diagnostics. I present recent improvements to PCR methodology, and describe some state-of-the-art detection methods and approaches used to diagnose various cancer markers, including ras genes, BCR/abl translocations, and G-proteins.
Lyons
J
J
Department of Molecular Biology, Cetus Corporation, Emeryville, California 94608.
D006801:Humans; D009369:Neoplasms / Q000175:diagnosis*; D016133:Polymerase Chain Reaction / Q000379:methods*