Autosomal dominant erythromelalgia.
We present a kindred of 29 persons affected with erythromelalgia (erythermalgia) in 5 generations. This paper updates the family reported by Burbank et al. [1966]. Patients have symptoms of intermittent intense burning limb pain related to increased skin temperature. No successful treatment has been identified, and the pathogenetic mechanism has not been established. Most affected individuals are female.
Finley
W H
WH
Department of Pediatrics, University of Alabama, Birmingham.
Lindsey
J R
JR
Fine
J D
JD
Dixon
G A
GA
Burbank
M K
MK
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002648:Child; D004916:Erythromelalgia / Q000235:genetics* / Q000503:physiopathology* / Q000628:therapy; D005260:Female; D005799:Genes, Dominant; D014644:Genetic Variation; D006801:Humans; D007249:Inflammation / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D010375:Pedigree
D000893:Anti-Inflammatory Agents