[The efficacy of the combined use of a lipid peroxidation inhibitor and a stimulator of the lymphatic drainage of the heart in the treatment of the acute period of myocardial infarction].
The effect of combined use of mannitol and alpha-tocopherol on the course and outcome of acute myocardial infarction has been studied. The results have shown that these drugs have a marked clinical effect. The ECG findings show that in the majority of cases the drugs prevented further development of necrotic process and the onset of life-threatening complications and accelerated normalization of the ECG parameters. The determination of serum enzyme activity and lipid peroxidation indexes has revealed a more prompt normalization of the above parameters in patients of the test group than in the controls. The use of the drugs under study in the earliest period of the disease development promotes the efficacy of the therapy performed.
Garaev
G Sh
GSh
Mamedov
Ia D
IaD
Kurbanov
Ia Z
IaZ
Ibragimli
F I
FI
Kasumova
R M
RM
D000328:Adult; D003864:Depression, Chemical; D004359:Drug Therapy, Combination; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects / Q000502:physiology; D008208:Lymphatic System / Q000187:drug effects / Q000502:physiology; D008353:Mannitol / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D013268:Stimulation, Chemical; D014810:Vitamin E / Q000008:administration & dosage / Q000627:therapeutic use*
D014810:Vitamin E; D008353:Mannitol
Effektivnost' kombinirovannogo primeneniia ingibitora perekisnogo okisleniia lipidov i stimuliatora limfodrenazha serdtsa v terapii ostrogo perioda infarkta miokarda.