[Change in the drug-metabolizing function of the liver in patients in the postoperative period in relation to the type of anesthesia].
Anesthesia-dependent changes in pharmaco-metabolic liver function have been studied in patients operated on for cosmetic facial defects. It has been established that the postoperative period in patients subjected intraoperatively to general combined anesthesia and controlled lung ventilation was characterized by inhibited drug metabolism in the liver, which required correction of the drug doses to reduce the risk of side and toxic effects of pharmacotherapy. Patients operated on under local procaine anesthesia had no considerable changes in pharmaco-metabolic liver function in the postoperative period.
Krakovskiĭ
M E
ME
Azimov
M I
MI
Ashirmetov
A Kh
AKh
D000328:Adult; D000772:Anesthesia, Local; D006591:Hexobarbital; D006801:Humans; D008099:Liver / Q000378:metabolism*; D008875:Middle Aged; D009458:Neuroleptanalgesia; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D011184:Postoperative Period; D011343:Procaine
D004364:Pharmaceutical Preparations; D011343:Procaine; D006591:Hexobarbital
Izmenenie farmakometaboliziruiushcheĭ funktsii pechenii u bol'nykh v posleoperatsionnom periode v zavisimosti vida anestezii.