Plasma atrial natriuretic peptide (ANP) in relation to blood pressure in severe hypertension.
Atrial natriuretic peptide-like immunoreactivity in plasma (ANP-LI) was studied in patients with severe hypertension (n = 21) and in matched healthy control subjects. There was no correlation between ANP-LI and blood pressure, and the distribution of ANP-LI values did not differ between the two groups. These results are consistent with the assumption that an increase in ANP is not caused by elevated blood pressure, although elevated ANP-LI may be found in subgroups of hypertensive subjects with increased atrial pressures due to, for example, cardiac failure.
Ekholm
D
D
Department of Internal Medicine, University of Lund, Sweden.
Edvinsson
L
L
Ekman
R
R
Thulin
T
T
D009320:Atrial Natriuretic Factor / Q000097:blood*; D001795:Blood Pressure Determination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood*; D008297:Male; D011187:Posture; D011863:Radioimmunoassay; D012720:Severity of Illness Index
D009320:Atrial Natriuretic Factor