title: Endoscopically directed fine needle aspiration biopsy of gastric and esophageal lesions.
abstract: Endoscopically directed fine needle aspiration (FNA) has been reported to be a valuable adjunct to forceps biopsy in the evaluation of gastric and esophageal lesions. In our series of 38 cases with endoscopically detected mucosal and submucosal abnormalities, FNAs were obtained with a Stifcor transbronchial aspiration needle. Four cases were reported as insufficient. Five aspirates correctly documented the presence of a neoplasm, but three failed to identify a subsequently histologically confirmed adenocarcinoma. Two cases were falsely suspicious for adenocarcinoma. FNA correctly excluded lymphoma in 12 patients with thick gastric folds clinically suspicious for lymphoma. FNA is a useful adjunct to forceps biopsy of neoplastic and inflammatory lesions in both mucosal and submucosal locations within the upper gastrointestinal tract.
authors.affiliation: Department of Pathology and Laboratory Medicine, University of California, Los Angeles School of Medicine.
authors.forename: L J
authors.initials: LJ
authors.lastname: Layfield
authors.forename: A
authors.initials: A
authors.lastname: Reichman
authors.forename: W M
authors.initials: WM
authors.lastname: Weinstein
mesh_terms: D001707:Biopsy, Needle / Q000379:methods*; D004379:Duodenal Neoplasms / Q000473:pathology*; D004938:Esophageal Neoplasms / Q000473:pathology*; D004945:Esophagoscopy; D005773:Gastroscopy; D006801:Humans; D013274:Stomach Neoplasms / Q000473:pathology*