[Metabolism of [1-(14)C]arachidonic acid in ruminant tissues during the pre- and postnatal periods of development under in vitro conditions].
After in vitro incubation of liver, skeletal muscle and adipose tissues from the fetuses and adult cattle as well as of placenta tissue with [1-14C]arachidonic acid, about 90% of the radioactive label was found in the lipids, 10%-in the prostaglandins, and 0.1%-in 14CO2. Arachidonic acid was utilized for the synthesis of lipids and prostaglandins in the majority of fetal tissues in a much greater degree, whereas that in energy-linked process--in a smaller degree compared with adult cattle tissues. [1-14C]arachidonic acid metabolism in the placenta and liver of the given species proceeds much more intensely than that in the skeletal muscles and adipose tissue. In tissues of adult animals [1-14C]arachidonic acid is predominantly utilized for the synthesis of phospholipids, whereas that in fetal tissues is utilized for the synthesis of phospholipids, cholesterol, esters and triglycerides.
Zakhariv
O Ia
OIa
Ianovich
V G
VG
D000273:Adipose Tissue / Q000196:embryology / Q000254:growth & development / Q000378:metabolism; D000818:Animals; D016718:Arachidonic Acid / Q000378:metabolism*; D005314:Embryonic and Fetal Development; D008099:Liver / Q000196:embryology / Q000254:growth & development / Q000378:metabolism; D024510:Muscle Development; D009132:Muscles / Q000196:embryology / Q000378:metabolism; D010920:Placenta / Q000196:embryology / Q000378:metabolism; D010929:Placentation; D012418:Ruminants / Q000196:embryology / Q000254:growth & development*
D016718:Arachidonic Acid
Metabolizm [1-(14)C]arakhindonovoĭ kisloty v tkaniakh zhvachnykh v prenatal'nyĭ i postnatal'nyĭ periody razvitiia v usloviiakh in vitro.