Selective IgA deficiency associated with glomerulonephritis and oligoarthritis.
A 59 year old woman with selective IgA deficiency associated with oligoarthritis and glomerulonephritis is described. She was seropositive for rheumatoid factor and renal histological examination showed a focal glomerulonephritis. High titre rheumatoid factor and a focal glomerulonephritis were also present in the only other well documented report of selective IgA deficiency and renal disease. Histological examination of the kidney suggested that the glomerulonephritis was mediated by immune complexes.
Camilleri
J P
JP
Department of Rheumatology, University Hospital of Wales, Cardiff, United Kingdom.
Moore
R H
RH
Griffiths
D F
DF
Williams
B D
BD
D000936:Antigen-Antibody Complex / Q000032:analysis; D001168:Arthritis / Q000209:etiology* / Q000276:immunology; D004406:Dysgammaglobulinemia / Q000150:complications*; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D006801:Humans; D017098:IgA Deficiency; D007678:Kidney Glomerulus / Q000473:pathology; D008875:Middle Aged; D012217:Rheumatoid Factor / Q000032:analysis
D000936:Antigen-Antibody Complex; D012217:Rheumatoid Factor