Sodium and blood pressure: the puzzling results of intrapopulation epidemiologic studies.
Most intrapopulation epidemiologic studies have been unable to find a significant association between sodium intake and blood pressure. The researchers have offered 2 opposing explanations: the hypothesis of the genetic susceptibility to sodium and the hypothesis of a weak association in general population. The evidence for and against each hypothesis is reviewed. The direction of future research is suggested.
Zhu
K
K
Department of Epidemiology, University of Washington, Seattle 98195.
Psaty
B M
BM
D000818:Animals; D001794:Blood Pressure; D006801:Humans; D006973:Hypertension / Q000453:epidemiology* / Q000209:etiology / Q000235:genetics; D008954:Models, Biological; D012982:Sodium, Dietary
D012982:Sodium, Dietary