Effect of thymic extract on blastogenic responses of chickens.
Chickens were treated intracoelomically with extracts of chicken thymus (TE) and bursa of Fabricius (BE), the former known to be enriched with avian thymic hormone. Doses of 1.0 mg TE enhanced blastogenic responses of peripheral blood lymphocytes to phytohemagglutinin (PHA) and concanavalin A for at least 3 wk after cessation of treatment. Very high doses of BE (5.0 mg) also enhanced blastogenic responses to PHA.
Murthy
K K
KK
Department of Avian Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602-4875.
Ragland
W L
WL
D000818:Animals; D002060:Bursa of Fabricius / Q000276:immunology*; D002478:Cells, Cultured; D002645:Chickens / Q000276:immunology*; D008213:Lymphocyte Activation / Q000187:drug effects*; D013949:Thymus Extracts / Q000494:pharmacology*; D013950:Thymus Gland / Q000276:immunology*; D014020:Tissue Extracts / Q000494:pharmacology
D013949:Thymus Extracts; D014020:Tissue Extracts