Coronary bypass using arterial grafts in homozygous familial hypercholesterolemia.
A 25-year-old man with homozygous familial hypercholesterolemia who had severe coronary artery disease underwent coronary revascularization by combined arterial grafts using bilateral internal mammary arteries and gastroepiploic artery. Early postoperative coronary angiography showed all the grafts patent without any stenosis. Because no atherosclerotic changes were seen in the specimens of each graft used, combined arterial grafting may have a role in the treatment of coronary artery disease in homozygous familial hypercholesterolemia.
Takahashi
T
T
First Department of Surgery, Osaka University Medical School, Japan.
Nakano
S
S
Kaneko
M
M
Matsuda
H
H
Taniguchi
K
K
Nakamura
T
T
Matsuzawa
Y
Y
D000328:Adult; D001158:Arteries / Q000637:transplantation*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000601:surgery*; D006720:Homozygote; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000150:complications* / Q000235:genetics; D007387:Internal Mammary-Coronary Artery Anastomosis; D008297:Male; D013270:Stomach / Q000098:blood supply; D014654:Vascular Patency