title: [Activity of Centella asiatica in venous insufficiency].
abstract: In this a review concerning TTFCA, its effects on metabolism in the connective tissue of the vascular wall and on the microcirculation are presented and discussed. This compound is effective in venous insufficiency, reducing ankle edema, foot swelling, capillary filtration rate and by improving microcirculatory parameters (RF, VAR PO2-PCO2). TTFCA displays a significant activity in venous hypertensive microangiopathy and its effects are dose-dependent.
authors.affiliation: Clinica Cardiovascolare, Università degli Studi G. D'Annunzio, Chieti.
authors.forename: M R
authors.initials: MR
authors.lastname: Cesarone
authors.forename: G
authors.initials: G
authors.lastname: Laurora
authors.forename: M T
authors.initials: MT
authors.lastname: De Sanctis
authors.forename: G
authors.initials: G
authors.lastname: Belcaro
mesh_terms: D006801:Humans; D008833:Microcirculation; D010936:Plant Extracts / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors; D014315:Triterpenes / Q000008:administration & dosage / Q000627:therapeutic use*; D014689:Venous Insufficiency / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D010936:Plant Extracts; C005084:TECA; D014315:Triterpenes
vernacular_title: Attività della Centella asiatica nell'insufficienza venosa.