Determination of the optical penetration depth in tumours from biopsy samples.
Tumours are examined in a simple sandwich structure which gives the samples a well defined shape and volume. Collimated light is scattered by the sample and analysed using a goniometer. It is found that tumours can be optically characterized by only two parameters. In phantoms, composed in order to approach closely the optical properties of tumours, a relationship is established experimentally between these parameters and the penetration depth. Using this relationship the penetration depth in tumours can be determined for 630 nm and 680 nm wavelength light.
Lenz
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Institut National de la Santé et de la Recherche Médicale, U281, Lyon, France.
D001706:Biopsy; D006801:Humans; D066298:In Vitro Techniques; D008027:Light; D008961:Models, Structural; D009369:Neoplasms / Q000188:drug therapy; D055095:Optics and Photonics; D010778:Photochemotherapy; D012542:Scattering, Radiation