title: Recombinant bovine somatotropin improves growth performance in finishing beef steers.
abstract: The objectives of this study were to determine the efficacy of various doses of rbST on ADG and feed efficiency (FE) and to describe carcass composition changes in finishing beef steers. In Exp. 1, 96 crossbred beef steers (393 kg) received daily i.m. injections of buffer or 33, 100, or 300 micrograms/kg of BW of rbST (0ST, 33ST, 100ST, 300ST). In Exp. 2, 200 crossbred beef steers (417 kg) received daily i.m. injections of buffer or 8.25, 16.5, 33, or 66 micrograms/kg of BW or rbST (0ST, 8.25ST, 16.5ST, 33ST, 66ST). Treatments were administered until steer BW per pen averaged 540 kg in Exp. 1 and 560 kg in Exp. 2. An 86% concentrate: 14% roughage diet was fed once daily (CP: 16.5% in Exp. 1, 20.2% in Exp. 2). In Exp. 1, growth performance of steers receiving rbST was dose-dependent; ADG changed linearly (P = .01), DMI decreased linearly (P = .03), and FE changed quadratically (P less than .03). The 33ST steers responded with improved ADG and FE, 100ST with improved FE, and 300ST with lower ADG and poorer FE, compared with 0ST. In Exp. 2, the ADG response was quadratic (P = .01), DMI decreased linearly (P = .003), and FE improved quadratically (P = .004) with increasing dose of rbST. Steers receiving 16.5ST and 33ST responded with improved ADG and FE, whereas steers receiving 8.25ST and 66ST responded with improved FE but not ADG relative to 0ST steers. In Exp. 1 and 2, rbST administration altered carcass composition by increasing carcass protein and decreasing carcass fat.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Performance Enhancement Research, Upjohn Company, Kalamazoo, MI 47001.
authors.forename: W M
authors.initials: WM
authors.lastname: Moseley
authors.forename: J B
authors.initials: JB
authors.lastname: Paulissen
authors.forename: M C
authors.initials: MC
authors.lastname: Goodwin
authors.forename: G R
authors.initials: GR
authors.lastname: Alaniz
authors.forename: W H
authors.initials: WH
authors.lastname: Claflin
mesh_terms: D000018:Abomasum / Q000187:drug effects / Q000473:pathology; D000273:Adipose Tissue / Q000187:drug effects / Q000254:growth & development; D000818:Animals; D001823:Body Composition / Q000187:drug effects*; D002417:Cattle / Q000254:growth & development*; D004435:Eating / Q000187:drug effects*; D013006:Growth Hormone / Q000097:blood / Q000494:pharmacology*; D007334:Insulin-Like Growth Factor I / Q000032:analysis; D007668:Kidney / Q000187:drug effects / Q000254:growth & development; D008099:Liver / Q000187:drug effects / Q000254:growth & development; D008297:Male; D008460:Meat / Q000032:analysis / Q000592:standards; D024510:Muscle Development; D009132:Muscles / Q000187:drug effects; D009929:Organ Size / Q000187:drug effects; D010903:Pituitary Gland, Anterior / Q000187:drug effects / Q000254:growth & development; D011897:Random Allocation; D011994:Recombinant Proteins / Q000494:pharmacology; D015430:Weight Gain / Q000187:drug effects*
chemical_list: D011994:Recombinant Proteins; D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone