title: Less common manifestations and presentations of Wegener's granulomatosis.
abstract: Wegener's granulomatosis is a clinicopathologic syndrome of unknown etiology characterized by granulomatous vasculitis of the upper and lower respiratory tracts and by glomerulonephritis. Virtually any organ system can be affected, and many patients present with unusual features of disease. During the period covered by this review, several articles reported atypical manifestations of Wegener's granulomatosis, including diffuse pulmonary infiltrates, lymphadenopathy, diffuse pulmonary hemorrhage, and overlap with giant cell arteritis. Unusual features of upper airway, eye, gastrointestinal, nervous system, and genitourinary tract disease were also described, and less common histopathologic features of pulmonary and nasal disease were characterized.
authors.affiliation: National Institutes of Health, Bethesda, Maryland.
authors.forename: R Y
authors.initials: RY
authors.lastname: Leavitt
authors.forename: A S
authors.initials: AS
authors.lastname: Fauci
mesh_terms: D005128:Eye Diseases / Q000209:etiology; D005767:Gastrointestinal Diseases / Q000209:etiology; D013700:Giant Cell Arteritis / Q000209:etiology; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008171:Lung Diseases / Q000209:etiology; D009422:Nervous System Diseases / Q000209:etiology; D012140:Respiratory Tract Diseases / Q000209:etiology