title: Secondary malignant neoplasms in patients with bladder carcinoma.
abstract: At the University of Pennsylvania and its affiliates, 292 patients with bladder carcinoma treated with a variety of definitive regimens were observed for the incidence of secondary malignancies. The cumulative incidence at fifty-four months, including synchronous primary neoplasms, was 24 percent. Hazard function analysis reveals a relatively constant risk of new neoplasms to be approximately 1.5 percent per year over a period of forty-eight months after diagnosis.
authors.affiliation: Department of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia.
authors.forename: K M
authors.initials: KM
authors.lastname: Greven
authors.forename: J A
authors.initials: JA
authors.lastname: Spera
authors.forename: L J
authors.initials: LJ
authors.lastname: Solin
authors.forename: R
authors.initials: R
authors.lastname: Whittington
authors.forename: A J
authors.initials: AJ
authors.lastname: Wein
authors.forename: G E
authors.initials: GE
authors.lastname: Hanks
mesh_terms: D006801:Humans; D015994:Incidence; D016609:Neoplasms, Second Primary / Q000453:epidemiology*; D016016:Proportional Hazards Models; D001749:Urinary Bladder Neoplasms / Q000473:pathology*