title: The search for effectors of beta-D-glucanases among marine invertebrates.
abstract: 1. The search for inhibitors and activators of endo-1----3-(EC 3.2.1.6) and 1----6-beta-D-glucanases (EC3.2.1) from marine mollusks in aqueous and ethanol extracts of various types of marine invertebrates, such as sponges, ascidians, coelenterates, echinoderms, dwelling in north seas (the sea of Okhotsk and the sea of Japan) and torrid seas (western coast of Australia) has been made. 2. A comparative analysis has shown that the overwhelming majority of extracts of animals, dwelling near Australia, inhibit beta-D-glucanases. 3. On the contrary, the extracts of animals dwelling in the sea of Okhotsk possess the activating effect, except for sponges of genera Haliclona whose sample extracts display a significant activating effect independently of their place of abode.
authors.affiliation: Pacific Institute of Bioorganic Chemistry, Russian Academy of Sciences, Vladivostok.
authors.forename: T N
authors.initials: TN
authors.lastname: Zvyagintseva
authors.forename: L A
authors.initials: LA
authors.lastname: Elyakova
authors.forename: V B
authors.initials: VB
authors.lastname: Krasohin
mesh_terms: D000818:Animals; D004789:Enzyme Activation; D004791:Enzyme Inhibitors / Q000302:isolation & purification; D004693:Glucan Endo-1,3-beta-D-Glucosidase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D007448:Invertebrates / Q000378:metabolism*; D008386:Marine Biology; D008974:Mollusca / Q000378:metabolism; D013045:Species Specificity
chemical_list: D004791:Enzyme Inhibitors; D006026:Glycoside Hydrolases; D004693:Glucan Endo-1,3-beta-D-Glucosidase; C020105:endo-1,6-beta-glucanase