High seminal sialic acid concentrations in patients with severe teratozoospermia.
Seminal plasma and sperm-bound sialic acid (SA) concentrations were evaluated in patients with severe teratozoospermia (less than 5% morphologically normal sperm) and correlated with values of a control group with greater than 20% morphologically normal sperm. The SA concentrations both in seminal plasma and on sperm were significantly higher in teratozoospermia, but the ratio of sperm-bound SA to seminal plasma SA remained virtually the same. The causes and consequences of high SA in these patients need further study.
du Toit
D
D
Department of Urology, University of Pretoria, South Africa.
Bornman
M S
MS
van der Merwe
M P
MP
du Plessis
D J
DJ
D006801:Humans; D008297:Male; D019158:N-Acetylneuraminic Acid; D012661:Semen / Q000378:metabolism*; D012794:Sialic Acids / Q000378:metabolism*; D013094:Spermatozoa / Q000002:abnormalities*
D012794:Sialic Acids; D019158:N-Acetylneuraminic Acid