title: Occupational hypersensitivity pneumonitis in a smelter exposed to zinc fumes.
abstract: A smelter exposed to zinc fumes reported severe recurrent episodes of cough, dyspnea and fever. Bronchoalveolar lavage showed a marked increase in lymphocytes count with predominance of CD8 T-lymphocytes. Presence of zinc in alveolar macrophages was assessed by analytic transmission electron microscopy. This is the first case of recurrent bronchoalveolitis related to zinc exposure in which the clinical picture and BAL results indicate a probable hypersensitivity pneumonitis.
authors.affiliation: Consultation de Pathologie Professionnelle, Hôpital Raymond Poincaré, Garches, France.
authors.forename: J
authors.initials: J
authors.lastname: Ameille
authors.forename: J M
authors.initials: JM
authors.lastname: Brechot
authors.forename: P
authors.initials: P
authors.lastname: Brochard
authors.forename: F
authors.initials: F
authors.lastname: Capron
authors.forename: M F
authors.initials: MF
authors.lastname: Dore
mesh_terms: D000328:Adult; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D000542:Alveolitis, Extrinsic Allergic / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D008669:Metallurgy; D009784:Occupational Diseases / Q000139:chemically induced* / Q000473:pathology; D015034:Zinc Oxide / Q000009:adverse effects*
chemical_list: D000395:Air Pollutants, Occupational; D015034:Zinc Oxide