Some unresolved issues in the physiology and biochemistry of phototransduction.
A number of recent review articles have discussed what is known about the events responsible for generating the electrical light response in vertebrate photoreceptors. The similarity of the material covered and the unanimity of the conclusions drawn have given rise to the popular, but false, impression that visual transduction is understood fully. The purpose of the present review is to dispell this notion by focusing on some of the unresolved issues.
Detwiler
P B
PB
University of Washington School of Medicine, Seattle.
Gray-Keller
M P
MP
D000818:Animals; D006801:Humans; D008027:Light; D010786:Photoreceptor Cells / Q000378:metabolism / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*