title: Characterisation of an antigenically unusual virus responsible for two outbreaks of Newcastle disease in the Republic of Ireland in 1990.
abstract: Antigenic characterisation of two highly virulent virus isolates from outbreaks of Newcastle disease on two closely connected farms in County Monaghan, Republic of Ireland, in 1990 showed the viruses to be indistinguishable but unlike other Newcastle disease viruses so far tested. However, they appeared to be antigenically closest to avirulent viruses isolated from waterfowl from several countries and from chickens in Northern Ireland in 1986. Despite the antigenic differences, chickens vaccinated with a live commercial Hitchner B1 vaccine were protected against intramuscular challenge with one of the virulent isolates.
authors.affiliation: Central Veterinary Laboratory, Weybridge, Surrey.
authors.forename: D J
authors.initials: DJ
authors.lastname: Alexander
authors.forename: G
authors.initials: G
authors.lastname: Campbell
authors.forename: R J
authors.initials: RJ
authors.lastname: Manvell
authors.forename: M S
authors.initials: MS
authors.lastname: Collins
authors.forename: G
authors.initials: G
authors.lastname: Parsons
authors.forename: M S
authors.initials: MS
authors.lastname: McNulty
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D000956:Antigens, Viral / Q000276:immunology*; D002645:Chickens; D004196:Disease Outbreaks / Q000662:veterinary*; D005260:Female; D006385:Hemagglutination Inhibition Tests; D007124:Immunoenzyme Techniques; D007494:Ireland / Q000453:epidemiology; D009521:Newcastle Disease / Q000453:epidemiology / Q000382:microbiology* / Q000517:prevention & control; D009522:Newcastle disease virus / Q000276:immunology* / Q000302:isolation & purification / Q000472:pathogenicity; D013047:Specific Pathogen-Free Organisms; D014611:Vaccination / Q000662:veterinary
chemical_list: D000911:Antibodies, Monoclonal; D000956:Antigens, Viral