PAF, eosinophils and asthma.
PAF has many inflammatory effects in the airways and closely mimics the pathophysiology of asthma. PAF is a potent stimulus to eosinophil accumulation and activation and may be involved in the eosinophilic inflammation which characterises asthma and airway hyperresponsiveness.
Barnes
P J
PJ
National Heart and Lung Institute, London, UK.
D001249:Asthma / Q000473:pathology*; D004804:Eosinophils / Q000166:cytology* / Q000276:immunology; D006801:Humans; D007249:Inflammation / Q000473:pathology; D010972:Platelet Activating Factor / Q000502:physiology*
D010972:Platelet Activating Factor