Measles cervicitis. Report of a case with cytologic and molecular biologic analysis.
We report on a 20-year-old woman who, in her third month of pregnancy, presented with a morbilliform rash, fever and diarrhea. Many multinucleate superficial, intermediate and metaplastic cells were noted in the cervical cytologic preparation. The presence of the measles virus in cells from the cervix was confirmed by the amplification of measles complementary DNA (cDNA) by the polymerase chain reaction. The patient's cervical Papanicolaou smear was unremarkable on reexamination four months after the onset of the disease. To our knowledge, this is the first verified reported case of infection of the uterine cervix by the measles virus.
Heimann
A
A
Department of Pathology, State University of New York, Stony Brook 11794.
Scanlon
R
R
Gentile
J
J
MacConnell
P
P
Nuovo
G J
GJ
D000328:Adult; D001483:Base Sequence; D005260:Female; D006801:Humans; D008457:Measles / Q000175:diagnosis / Q000473:pathology; D008459:Measles virus / Q000302:isolation & purification*; D008969:Molecular Sequence Data; D065006:Papanicolaou Test; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology* / Q000473:pathology; D002575:Uterine Cervicitis / Q000382:microbiology* / Q000473:pathology; D014626:Vaginal Smears