title: Advancing conservative treatment of ectopic pregnancy--laparoscopic and "non-surgical" management.
abstract: Improvements in diagnostic measures have contributed to the earlier diagnosis of ectopic pregnancy which in turn has led to the development of new and alternative methods of managing tubal pregnancies. Laparoscopic salpingotomy offers advantages such as a reduction in operating time and shorter hospital stays and convalescence as compared with conventional abdominal surgery. Furthermore, neither the frequency of persistent trophoblasts nor of second operations is increased, and the subsequent fertility rate is at least equal to that after laparotomy. "Non-surgical" treatment of ectopic pregnancy, such as systemic administration of methotrexate and laparoscopic/transvaginal ultrasonic--guided local injection of methotrexate, prostaglandins or hyperosmolar glucose, are attractive alternative methods in selected cases. These methods are safe and effective and have a high success rate and promising results for fertility. Laparoscopy is preferred to conventional abdominal surgery for the treatment of ectopic pregnancy. In selected cases, "non-surgical" treatment can be an attractive alternative therapy.
authors.affiliation: Department of Obstetrics and Gynaecology, University of Göteborg, Sweden.
authors.forename: J
authors.initials: J
authors.lastname: Thorburn
mesh_terms: D015237:Dinoprost / Q000008:administration & dosage*; D015232:Dinoprostone / Q000008:administration & dosage*; D005187:Fallopian Tubes / Q000187:drug effects* / Q000601:surgery; D005260:Female; D005947:Glucose / Q000008:administration & dosage*; D006801:Humans; D015552:Injections, Intralesional; D010535:Laparoscopy; D008727:Methotrexate / Q000008:administration & dosage*; D011247:Pregnancy; D011274:Pregnancy, Tubal / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery; D011296:Prenatal Diagnosis / Q000379:methods / Q000639:trends; D013997:Time Factors
chemical_list: D015237:Dinoprost; D005947:Glucose; D015232:Dinoprostone; D008727:Methotrexate