title: Intraperitoneal chemotherapy versus no treatment in patients with ovarian carcinoma who are in complete clinical remission.
abstract: BACKGROUND
  The optimal management of patients with ovarian carcinoma who are in complete clinical remission after completion of postoperative cisplatin-based chemotherapy has not been established.
  
  
  METHODS
  In this study, the outcomes of two groups of such patients were compared. One group of 25 patients underwent a second-look laparotomy and subsequently received three courses of intraperitoneal chemotherapy (IP group). The other group of 12 patients was not reexplored and received no additional treatment (NT group).
  
  
  RESULTS
  A trend for better survival in the IP group was found compared with the NT group. There was no difference in the duration of the progression-free interval.
  
  
  CONCLUSIONS
  More effective treatment for the consolidation of complete clinical remission in patients with ovarian carcinoma is needed.
authors.affiliation: Department of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer, Israel.
authors.forename: J
authors.initials: J
authors.lastname: Menczer
authors.forename: G
authors.initials: G
authors.lastname: Ben-Baruch
authors.forename: S
authors.initials: S
authors.lastname: Rizel
authors.forename: H
authors.initials: H
authors.lastname: Brenner
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007274:Injections, Intraperitoneal; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000601:surgery*; D012074:Remission Induction; D012086:Reoperation; D016019:Survival Analysis
chemical_list: D002945:Cisplatin