Two-year changes in mandibular bone mass in an osteoporotic population.
Deficiency of 1,25 Dihydroxycholecalciferol (the active form of vitamin D) may be a major factor contributing to osteoporosis. This study measured mandibular bone mass over 2 years in women with postmenopausal osteoporosis and evaluated whether 1,25 Dihydroxycholecalciferol increased mandibular bone mass. All subjects increased dietary calcium to 1000 mg per day and took a multivitamin supplement with 400 IU of vitamin D daily. There was a large variation in the amount of change in mandibular bone mass, but no significant difference attributed to the administration of 1,25 Dihydroxycholecalciferol. With those dietary and vitamin supplements, 83% of the subjects were able to maintain or increase their mandibular bone mass.
Kribbs
P J
PJ
University of Washington, School of Dentistry, Seattle.
D015502:Absorptiometry, Photon; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D002117:Calcitriol / Q000008:administration & dosage / Q000627:therapeutic use*; D002136:Calcium, Dietary / Q000008:administration & dosage; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007575:Jaw, Edentulous / Q000473:pathology / Q000503:physiopathology; D008334:Mandible / Q000187:drug effects / Q000473:pathology*; D008593:Menopause; D008875:Middle Aged; D010024:Osteoporosis / Q000473:pathology* / Q000503:physiopathology; D010919:Placebos; D014815:Vitamins / Q000008:administration & dosage
D002136:Calcium, Dietary; D010919:Placebos; D014815:Vitamins; D002117:Calcitriol