title: The multiple-minima problem in small peptides revisited. The Threshold Accepting approach.
abstract: A recently reported optimization method, known as Threshold Accepting, was tested for the purpose of locating the structure of several peptide molecules with the lowest conformational energy. A comparison with previous results obtained with the Simulated Annealing technique was made. Our study indicate Threshold Accepting as a better technique in locating such structures.
authors.affiliation: Instituto de Física, Universidad Nacional Autonoma de México, Cuernavaca, Morelos.
authors.forename: L B
authors.initials: LB
authors.lastname: Morales
authors.forename: R
authors.initials: R
authors.lastname: Garduño-Juárez
authors.forename: D
authors.initials: D
authors.lastname: Romero
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D005998:Glycine / Q000737:chemistry; D007930:Leucine / Q000737:chemistry; D008715:Methionine / Q000737:chemistry; D009842:Oligopeptides / Q000737:chemistry*; D010649:Phenylalanine / Q000737:chemistry; D011487:Protein Conformation; D014443:Tyrosine / Q000737:chemistry
chemical_list: D009842:Oligopeptides; D014443:Tyrosine; D010649:Phenylalanine; D008715:Methionine; D007930:Leucine; D005998:Glycine