A prospective survey of drug induced hepatotoxicity in a large hospital.
A prospective survey of laboratory records was carried out to identify the extent of drug induced hepatotoxicity in a hospital population. Eleven of 1000 (1.1%) abnormal liver function tests were due to drug induced hepatotoxicity. Anti-tubercular drugs, viz isoniazid, rifampicin and pyrazinamide were responsible for all cases of serious hepatotoxicity.
Kshirsagar
N A
NA
Department of Pharmacology, Seth G S Medical College, Parel, Bombay.
Karande
S C
SC
Potkar
C N
CN
D000328:Adult; D000995:Antitubercular Agents / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies
D000995:Antitubercular Agents