title: The polymerase chain reaction and cancer diagnostics.
abstract: In this review, I describe the polymerase chain reaction (PCR) and its application to cancer diagnostics. I present recent improvements to PCR methodology, and describe some state-of-the-art detection methods and approaches used to diagnose various cancer markers, including ras genes, BCR/abl translocations, and G-proteins.
authors.affiliation: Department of Molecular Biology, Cetus Corporation, Emeryville, California 94608.
authors.forename: J
authors.initials: J
authors.lastname: Lyons
mesh_terms: D006801:Humans; D009369:Neoplasms / Q000175:diagnosis*; D016133:Polymerase Chain Reaction / Q000379:methods*