title: [Serum selenium level as a diagnostic parameter in breast cancer].
abstract: The level of selenium in blood serum was determined in 33 patients with breast cancer, 13 women with verified mastopathy, and 43 healthy subjects from the Zagreb area. In the second and third quartiles the values of selenium obtained from sick subjects (41-58 micrograms/l) and healthy subjects (73-89 micrograms/l) differed significantly (p less than 0.001). In the group of subjects with mastopathy, serum selenium in the same way ranged from 67-70 micrograms/l and did not differ significantly from the group of healthy women, but differed significantly from the patients with breast cancer (p less than 0.001). Such a result leads to the conclusion that determination of selenium in the blood could be used as a noninvasive diagnostic parameter in clinical assessment of malignant breast disease.
authors.affiliation: Institute for Medical Research and Occupational Health, Zagreb, Croatia.
authors.forename: H
authors.initials: H
authors.lastname: Krsnjavi
authors.forename: D
authors.initials: D
authors.lastname: Beker
mesh_terms: D000230:Adenocarcinoma / Q000097:blood* / Q000473:pathology; D001943:Breast Neoplasms / Q000097:blood* / Q000473:pathology; D005260:Female; D005348:Fibrocystic Breast Disease / Q000097:blood / Q000473:pathology; D006801:Humans; D009367:Neoplasm Staging; D012016:Reference Values; D012643:Selenium / Q000097:blood*
chemical_list: D012643:Selenium
vernacular_title: Seleniumspiegel im Serum als diagnostischer Parameter bei Mammakarzinom.