Spontaneous regression of acquired immune deficiency syndrome-related, high-grade, extranodal non-Hodgkin's lymphoma.
Spontaneous regression of low-grade non-Hodgkin's lymphoma often has been reported. Proposed mechanisms of this event have included concomitant infections and enhanced cellular and humoral antitumor responses by the host. Spontaneous regression of high-grade non-Hodgkin's lymphoma is rare and has never been reported in a patient with acquired immune deficiency syndrome (AIDS). The authors report a patient with spontaneous regression of AIDS-related non-Hodgkin's lymphoma and discuss the role of host immunity in mediating spontaneous regression.
Karnad
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AB
Department of Internal Medicine, James H. Quillen College of Medicine, East Tennessee State University, Johnson City 37614.
Jaffar
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A
Lands
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RH
D000328:Adult; D000917:Antibody Formation; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000276:immunology; D008228:Lymphoma, Non-Hodgkin / Q000276:immunology; D008297:Male; D009365:Neoplasm Regression, Spontaneous / Q000276:immunology