title: The murine MHC encodes a mammalian homolog of bacterial ribosomal protein S13.
abstract: The mouse major histocompatibility complex (MHC) contains many genes in addition to the classical immune response genes. We have screened overlapping cosmid clones covering 170 kb of the H-2K region for genes expressed in embryonal carcinoma (EC) cells. The Ke-3 gene (Abe et al. 1988) found in this region was further studied by Southern, Northern, and sequence analysis. It is an expressed, intron-containing locus encoding a mouse homolog of the bacterial ribosomal protein S13. This is the first non-organelle S13 homolog identified in metazoans, and its genomic location has been determined precisely.
authors.affiliation: Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142.
authors.forename: A J
authors.initials: AJ
authors.lastname: MacMurray
authors.forename: H S
authors.initials: HS
authors.lastname: Shin
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015152:Blotting, Northern; D015139:Blotting, Southern; D003001:Cloning, Molecular; D003360:Cosmids; D004247:DNA; D008285:Major Histocompatibility Complex / Q000235:genetics*; D051379:Mice; D008969:Molecular Sequence Data; D015183:Restriction Mapping; D012269:Ribosomal Proteins / Q000235:genetics*; D016415:Sequence Alignment; D014158:Transcription, Genetic
chemical_list: D012269:Ribosomal Proteins; D004247:DNA