title: The rel family of proteins.
abstract: The rel family of proteins can be defined as a group of proteins that share sequence homology over a 300 amino acid region termed the rel domain. The rel family comprises important regulatory proteins from a wide variety of species and includes the Drosophila morphogen dorsal, the mammalian transcription factor NF-kappa B, the avian oncogene v-rel, and the cellular proto-oncogene c-rel. Over the last two years it has become apparent that these proteins function as DNA-binding transcription factors, and that their activity is regulated at the level of subcellular localization.
authors.affiliation: Department of Cell and Developmental Biology, Roche Research Center, Nutley, New Jersey 07110.
authors.forename: C
authors.initials: C
authors.lastname: Rushlow
authors.forename: R
authors.initials: R
authors.lastname: Warrior
mesh_terms: D000818:Animals; D001483:Base Sequence; D004268:DNA-Binding Proteins; D004330:Drosophila / Q000235:genetics; D015757:Genes, rev; D006801:Humans; D008969:Molecular Sequence Data; D015513:Oncogene Proteins; D000090063:Proto-Oncogene Mas; D011518:Proto-Oncogene Proteins; D012097:Repressor Proteins; D016415:Sequence Alignment; D015534:Trans-Activators
chemical_list: D004268:DNA-Binding Proteins; C000715470:MAS1 protein, human; D015513:Oncogene Proteins; D000090063:Proto-Oncogene Mas; D011518:Proto-Oncogene Proteins; D012097:Repressor Proteins; D015534:Trans-Activators