title: Production of pyrogenic exotoxins in group A streptococci isolated from patients in Zagreb, Croatia.
abstract: The pyrogenic exotoxin profiles were determined of group A streptococci isolated from patients in Zagreb, Croatia in the period 1989-1990. A total of 12 strains were studied, five from patients with serious infections and seven from patients with uncomplicated infections. Serotypes M1 and M3 were found in seven (58%) patients. Seven strains produced exotoxin A and ten strains exotoxin B. The proportion of exotoxin A and B producing strains in patients with severe infections (3 patients respectively) was similar to that found in patients with uncomplicated infections (4 and 7 patients respectively).
authors.affiliation: University Hospital of Infectious Diseases Dr Fran Mihaljovic, Zagreb, Croatia.
authors.forename: J
authors.initials: J
authors.lastname: Begovac
authors.forename: B
authors.initials: B
authors.lastname: Gmajnicki
authors.forename: P M
authors.initials: PM
authors.lastname: Schlievert
authors.forename: D R
authors.initials: DR
authors.lastname: Johnson
authors.forename: E L
authors.initials: EL
authors.lastname: Kaplan
mesh_terms: D000328:Adult; D000368:Aged; D001426:Bacterial Proteins; D002648:Child; D002675:Child, Preschool; D005098:Exotoxins / Q000096:biosynthesis*; D005260:Female; D006801:Humans; D008297:Male; D008565:Membrane Proteins; D011749:Pyrogens / Q000096:biosynthesis*; D013297:Streptococcus pyogenes / Q000378:metabolism*; D015022:Yugoslavia
chemical_list: D001426:Bacterial Proteins; D005098:Exotoxins; D008565:Membrane Proteins; D011749:Pyrogens; C117980:SpeA protein, Streptococcus pyogenes; C027951:erythrogenic toxin