Primary hepatic leiomyosarcoma in a child with the acquired immunodeficiency syndrome.
We report the first case of acquired immunodeficiency syndrome (AIDS)-related primary hepatic leiomyosarcoma in a 9-year-old girl. The pathologic diagnosis was made on a partial hepatectomy specimen and was confirmed by immunohistochemistry and electron microscopy. No human immunodeficiency virus-related nucleic acid was identified in tumor cells by in situ hybridization. Review of the AIDS-related literature reveals a rising incidence of tumors of smooth muscle origin in human immunodeficiency virus-infected patients. This case study details the eighth pediatric AIDS patient with a tumor of smooth muscle origin and represents the 20th and the youngest patient with primary hepatic leiomyosarcoma to be reported in the world literature.
Ross
J S
JS
Department of Pathology and Laboratory Medicine, Albany Medical College, NY 12208.
Del Rosario
A
A
Bui
H X
HX
Sonbati
H
H
Solis
O
O
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D002648:Child; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000150:complications* / Q000473:pathology; D008113:Liver Neoplasms / Q000150:complications* / Q000473:pathology