title: Impact of gastric restrictive surgery on hypertension in the morbidly obese.
abstract: Hypertension is a major health risk factor in patients who are morbidly obese. Two hundred eighty-nine morbidly obese patients undergoing gastric restrictive surgery were evaluated for the presence of hypertension (blood pressure greater than or equal to 160/90 mm Hg or currently undergoing antihypertensive therapy) pre- and postoperatively. Of 74 (26%) preoperatively hypertensive patients, 67 (91%) were available for follow-up. Preoperative hypertension resolved in 66% (44 of 67) of patients following gastric restrictive surgery. Superobese and morbidly obese patients had similar reductions in hypertension after surgery (69% versus 63%). Patients not receiving antihypertensives preoperatively had a greater reduction of hypertension than those medically treated preoperatively (78% versus 58%). The amount of weight loss significantly predicted the reduction of hypertension, whereas follow-up weight achieved did not. The amounts of weight loss for patients with resolved and persistent hypertension were 89.3 +/- 5.6 lbs (mean +/- standard error of the mean +ADSEM+BD) and 66.0 +/- 8.3 lbs, respectively (p less than 0.02). For patients with resolved hypertension, follow-up weights for the morbidly obese and superobese were 162.0 +/- 10.8 lbs (133% +/- 4% ideal body weight +ADIBW+BD) and 220.4 +/- 9.5 lbs (170% +/- 7% IBW). Gastric restrictive surgery is effective therapy for hypertension in morbidly obese patients. Patients need not achieve weights approaching IBW to enjoy the benefits of gastric restrictive surgery on hypertension.
authors.affiliation: Department of General Surgery, New England Deaconess Hospital, Harvard Medical School, Boston, Massachusetts 02215.
authors.forename: E F
authors.initials: EF
authors.lastname: Foley
authors.forename: P N
authors.initials: PN
authors.lastname: Benotti
authors.forename: B C
authors.initials: BC
authors.lastname: Borlase
authors.forename: J
authors.initials: J
authors.lastname: Hollingshead
authors.forename: G L
authors.initials: GL
authors.lastname: Blackburn
mesh_terms: D000328:Adult; D001794:Blood Pressure; D005260:Female; D005500:Follow-Up Studies; D015390:Gastric Bypass; D015391:Gastroplasty; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000503:physiopathology*; D008297:Male; D009767:Obesity, Morbid / Q000150:complications / Q000601:surgery*; D015431:Weight Loss