title: Pain upon eye movement following digoxin absorption.
abstract: A patient who had received digoxin for 6 months experienced glare and ocular pain induced by eye movement. The symptoms lasted for 2 days and disappeared within hours after the treatment was discontinued. Four months later, digoxin was readministered. After 2 days, the symptoms reappeared but disappeared again within hours of stopping treatment. The origin of the pain is uncertain, although mechanisms related to optic nerve or ocular muscle involvement should be considered. Digoxin toxicity should be included in the differential diagnosis of pain evoked by ocular movements.
authors.affiliation: Department of Ophthalmology, Geneva University Hospital, Switzerland.
authors.forename: A
authors.initials: A
authors.lastname: Mermoud
authors.forename: A B
authors.initials: AB
authors.lastname: Safran
authors.forename: N
authors.initials: N
authors.lastname: de Stoutz
mesh_terms: D000328:Adult; D004077:Digoxin / Q000009:adverse effects* / Q000627:therapeutic use; D005133:Eye Movements / Q000502:physiology*; D005260:Female; D006801:Humans; D010146:Pain / Q000139:chemically induced* / Q000503:physiopathology; D014339:Truncus Arteriosus, Persistent / Q000188:drug therapy; D014786:Vision Disorders / Q000139:chemically induced
chemical_list: D004077:Digoxin