title: High seminal sialic acid concentrations in patients with severe teratozoospermia.
abstract: Seminal plasma and sperm-bound sialic acid (SA) concentrations were evaluated in patients with severe teratozoospermia (less than 5% morphologically normal sperm) and correlated with values of a control group with greater than 20% morphologically normal sperm. The SA concentrations both in seminal plasma and on sperm were significantly higher in teratozoospermia, but the ratio of sperm-bound SA to seminal plasma SA remained virtually the same. The causes and consequences of high SA in these patients need further study.
authors.affiliation: Department of Urology, University of Pretoria, South Africa.
authors.forename: D
authors.initials: D
authors.lastname: du Toit
authors.forename: M S
authors.initials: MS
authors.lastname: Bornman
authors.forename: M P
authors.initials: MP
authors.lastname: van der Merwe
authors.forename: D J
authors.initials: DJ
authors.lastname: du Plessis
mesh_terms: D006801:Humans; D008297:Male; D019158:N-Acetylneuraminic Acid; D012661:Semen / Q000378:metabolism*; D012794:Sialic Acids / Q000378:metabolism*; D013094:Spermatozoa / Q000002:abnormalities*
chemical_list: D012794:Sialic Acids; D019158:N-Acetylneuraminic Acid