Sarcomatoid carcinoma of the bladder: a case report.
We reported a case of sarcomatoid carcinoma of the bladder in a 78-year-old woman presenting with pollakisuria. She has remained well without any evidence of recurrence for 25 months after radical cystectomy. Microscopic examination revealed a composition almost exclusively of spindle and dedifferentiated cells, accompanied by only a few cells retaining epithelial features of differentiation. The latter cells were immunohistochemically positive for epithelial membrane antigen (EMA). A concomitant carcinoma in situ was present in the adjacent mucosa. Immunohistochemical exploration with EMA proved useful for reinforcing the conventional histological diagnosis.
Takashi
M
M
Department of Urology, Nagoya University School of Medicine.
Sakata
T
T
Nakano
Y
Y
Nagai
T
T
Miyake
K
K
D000368:Aged; D000951:Antigens, Neoplasm / Q000378:metabolism; D002277:Carcinoma / Q000175:diagnosis* / Q000276:immunology; D002278:Carcinoma in Situ / Q000175:diagnosis / Q000276:immunology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008562:Membrane Glycoproteins / Q000378:metabolism; D018396:Mucin-1; D012509:Sarcoma / Q000175:diagnosis* / Q000276:immunology; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000276:immunology
D000951:Antigens, Neoplasm; D008562:Membrane Glycoproteins; D018396:Mucin-1