title: Papillary thyroid cancer and its surgical management.
abstract: The surgical management in papillary thyroid cancer has been highly controversial. In the Department of Surgery (II), Kanazawa University Hospital, the surgical management especially for cervical lymph node metastases has changed since 1973 from a conservative approach to an aggressive one. In order to determine whether an aggressive approach is warranted, a retrospective multivariate analysis was carried out on 106 cases of papillary thyroid cancer. The patients have been followed for 10-28 years. Multivariate analysis was conducted following Cox's model. By this analysis, aggressive management appeared to have no impact on survival or relapse-free survival. However, age, sex, tumor size, and cervical lymphadenopathy were confirmed to be important prognostic factors in survival and/or relapse-free survival.
authors.affiliation: Operation Center, Kanazawa University Hospital, School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Noguchi
authors.forename: M
authors.initials: M
authors.lastname: Earashi
authors.forename: H
authors.initials: H
authors.lastname: Kitagawa
authors.forename: N
authors.initials: N
authors.lastname: Ohta
authors.forename: M
authors.initials: M
authors.lastname: Thomas
authors.forename: I
authors.initials: I
authors.lastname: Miyazaki
authors.forename: Y
authors.initials: Y
authors.lastname: Mizukami
authors.forename: T
authors.initials: T
authors.lastname: Michigishi
mesh_terms: D000328:Adult; D002291:Carcinoma, Papillary / Q000401:mortality / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate; D013964:Thyroid Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D013965:Thyroidectomy / Q000379:methods; D016896:Treatment Outcome