The pharmacotherapy of minor depression.
Although the literature appears to demonstrate the efficacy of standard antidepressant medications for the short-term treatment of patients with minor depression, they are not widely prescribed. In comparison, psychotherapy is generally recommended, but without convincing data to support this conviction. We, therefore, advocate successive trials with antidepressants in any depressed patient, particularly if they have failed to benefit from psychotherapy or other supportive measures for three months.
Stewart
J W
JW
New York State Psychiatric Institute, New York 10032.
Quitkin
F M
FM
Klein
D F
DF
D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003866:Depressive Disorder / Q000188:drug therapy*; D004311:Double-Blind Method; D005260:Female; D005473:Fluoxetine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D007099:Imipramine / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D008996:Monoamine Oxidase Inhibitors / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D010919:Placebos
D000929:Antidepressive Agents, Tricyclic; D008996:Monoamine Oxidase Inhibitors; D010919:Placebos; D005473:Fluoxetine; D007099:Imipramine