Intracranial inflammatory pseudotumor.
An intracranial mass thought clinically and by computed tomography and angiography to be a meningioma proved to be an inflammatory pseudotumor. The lesion was composed of sheets of mature plasma cells and lymphocytes with germinal center formation. Immunohistochemical studies revealed a polyclonal cell population, supporting a diagnosis of a reactive lesion rather than a plasma cell neoplasm. Inflammatory pseudotumor should be considered in the differential diagnosis of a sharply demarcated intracranial mass clinically and radiologically diagnosed as meningioma.
Sitton
J E
JE
Department of Pathology, Tulane University School of Medicine, New Orleans, Louisiana 70112.
Harkin
J C
JC
Gerber
M A
MA
D000368:Aged; D000369:Aged, 80 and over; D001927:Brain Diseases / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D005625:Frontal Lobe / Q000473:pathology; D006104:Granuloma, Plasma Cell / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D014057:Tomography, X-Ray Computed