title: The dilemma of a low rate of chromosomal mosaicism found in fetal blood sampling.
abstract: We report a case in which mosaicism of trisomy 13 was detected in 4/10 cells (40 per cent) in amniotic fluid cell cultures, followed by a low rate of mosaicism (1/160 cells) detected in a fetal blood sample. This finding presents a dilemma both for the genetic counsellor and for the parents in determining whether or not to terminate the pregnancy.
authors.affiliation: Genetics Unit, Sapir Medical Center, Kfar Saba, Israel.
authors.forename: M
authors.initials: M
authors.lastname: Fejgin
authors.forename: I
authors.initials: I
authors.lastname: Barnes
authors.forename: N
authors.initials: N
authors.lastname: Lipnick
authors.forename: Z
authors.initials: Z
authors.lastname: Magid
authors.forename: G
authors.initials: G
authors.lastname: Kohn
authors.forename: A
authors.initials: A
authors.lastname: Amiel
mesh_terms: D000328:Adult; D002882:Chromosomes, Human, Pair 13; D003937:Diagnosis, Differential; D005260:Female; D005312:Fetal Blood / Q000166:cytology; D005817:Genetic Counseling; D006801:Humans; D007621:Karyotyping; D009030:Mosaicism; D011296:Prenatal Diagnosis; D014314:Trisomy