title: Thrombolytic therapy: a state of the art review.
abstract: The plasminogen-plasmin enzyme system and its therapeutic manipulation provide the substrate for an assessment of the clinical use of thrombolytic agents. Proven effective in acute MI and its complications, such agents have other potential applications--e.g., in stroke or pulmonary embolism--and are being investigated in those contexts.
authors.affiliation: Department of Internal Medicine, University of Texas Health Science Center, Houston.
authors.forename: C R
authors.initials: CR
authors.lastname: Benedict
authors.forename: S
authors.initials: S
authors.lastname: Mueller
authors.forename: H V
authors.initials: HV
authors.lastname: Anderson
authors.forename: J T
authors.initials: JT
authors.lastname: Willerson
mesh_terms: D002318:Cardiovascular Diseases / Q000188:drug therapy; D005341:Fibrinolysin / Q000502:physiology; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D009203:Myocardial Infarction / Q000188:drug therapy*; D010958:Plasminogen / Q000502:physiology; D015912:Thrombolytic Therapy
chemical_list: D005343:Fibrinolytic Agents; D010958:Plasminogen; D005341:Fibrinolysin