Change of alcohol dehydrogenase activity in sera after alcoholism treatment.
Increased metabolic alcohol tolerance was found in chronic non-cirrhotic alcoholics after alcoholism treatment with disulfiram. This increased metabolic alcohol tolerance is connected with an increased activity of alcohol dehydrogenase due to the healing of hepatic tissue damage. This increase in alcohol dehydrogenase activity can help in monitoring the effectiveness of treatments for alcoholic liver disease.
Buris
L
L
Institute of Forensic Medicine, Medical University of Debrecen, Hungary.
Varga
M
M
D000328:Adult; D000426:Alcohol Dehydrogenase / Q000097:blood*; D000437:Alcoholism / Q000188:drug therapy* / Q000201:enzymology* / Q000378:metabolism; D004221:Disulfiram / Q000627:therapeutic use; D000431:Ethanol / Q000009:adverse effects / Q000378:metabolism; D005260:Female; D006801:Humans; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D008875:Middle Aged
D000431:Ethanol; D000426:Alcohol Dehydrogenase; D004221:Disulfiram