title: [Clinical experiences with thymopentin administered by intra- and periarticular routes in degenerative pathology of the shoulder, knee and hip].
abstract: The aim of this study was to assess the efficacy and tolerability of thymopentin, a synthetic pentapeptide with an immunomodulating action, in treating patients suffering from gonarthrosis, coxarthrosis and scapolo-omeral periarthritis by evaluating pain when resting, during activity and in response to digital pressure. Painful symptoms, quantified according to Scott-Huskisson's scale, disappeared in the majority of patients two months after the end of treatment. No collateral effects were recorded. Thymopentin may therefore be put forward as a useful alternative to cortisone compounds in the treatment of not severe degenerative joint pathologies.
authors.affiliation: Istituto di Clinica Ortopedica e Traumatologica, Università degli Studi di Modena.
authors.forename: S
authors.initials: S
authors.lastname: Zanasi
authors.forename: A
authors.initials: A
authors.lastname: Caroli
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007322:Instillation, Drug; D007719:Knee Joint; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy*; D015207:Osteoarthritis, Hip / Q000188:drug therapy*; D010489:Periarthritis / Q000188:drug therapy*; D012785:Shoulder Joint; D016305:Thymopentin / Q000008:administration & dosage*
chemical_list: D016305:Thymopentin
vernacular_title: Esperienze cliniche con timopentina per via intra- e periarticolare nella patologia degenerativa della spalla, del ginocchio, dell'anca.