title: MRI in the diagnosis of primary lymphoma of bone: correlation with histopathology.
abstract: Seven patients with primary non-Hodgkin lymphoma of the skeleton were examined with MRI. The results were compared to "small cell" primary malignant bone tumors. The latter showed marked hyperintensity on SE T2-weighted images; in contrast, the lymphomas appeared as inhomogeneous lesions of low signal intensity on T2-weighted images. Histologic examination with silver stains of specimens of these lesions revealed a high content of fibrous tissue, which could explain the signal behavior on MR. All seven lymphomas were located in the epiphysis or metaphysis of the appendicular skeleton; intraarticular tumor growth was demonstrated in five cases.
authors.affiliation: MR Institute, University of Vienna, Austria.
authors.forename: R
authors.initials: R
authors.lastname: Stiglbauer
authors.forename: I
authors.initials: I
authors.lastname: Augustin
authors.forename: J
authors.initials: J
authors.lastname: Kramer
authors.forename: H
authors.initials: H
authors.lastname: Schurawitzki
authors.forename: H
authors.initials: H
authors.lastname: Imhof
authors.forename: T
authors.initials: T
authors.lastname: Radaszkiewicz
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000473:pathology; D002648:Child; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged