One hundred requests for predictive testing for Huntington's disease.
In Grampian region, the first 100 requests for predictive testing for Huntington's disease have been analysed. Forty-five presymptomatic predictive test results have been given, eleven families have made a decision to undergo prenatal exclusion tests, and so far eleven pregnancies have been investigated using chorion villus biopsy. This paper presents the protocol used and a descriptive analysis of those receiving results, those choosing to leave the programme, and those unable to complete it because of an unsuitable family structure or unco-operative relatives.
Simpson
S A
SA
Medical Genetics, Medical School, University of Aberdeen, UK.
Besson
J
J
Alexander
D
D
Allan
K
K
Johnston
A W
AW
D000328:Adult; D016009:Chi-Square Distribution; D005260:Female; D005817:Genetic Counseling; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D006816:Huntington Disease / Q000175:diagnosis* / Q000235:genetics / Q000523:psychology; D007258:Informed Consent; D008297:Male; D011237:Predictive Value of Tests; D012606:Scotland