Can the magnesium content of mononuclear blood cells be altered by oral magnesium supplementation?
A randomized, double-blind, placebo-controlled trial was performed on a rigorously defined group of normal subjects to see if magnesium (Mg) supplementation could affect serum Mg levels or Mg content of mononuclear blood cells. Forty-nine subjects were randomized to either placebo, tablets containing 90% United States recommended daily allowance (USRDA) of Mg, or tablets containing 180% USRDA of Mg. We were unable to demonstrate a statistically significant increase in Mg content of mononuclear blood cells.
Desbiens
N A
NA
Marshfield Clinic, Marshfield Medical Research Foundation, WI 54449.
Marx
J J
JJ
Haas
R G
RG
Reinhart
R A
RA
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000378:metabolism*; D008274:Magnesium / Q000097:blood* / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D013054:Spectrophotometry, Atomic
D008274:Magnesium