Enhanced prevalence of ankyloglossia with maternal cocaine use.
A series of 500 term neonates was examined in a well-baby nursery, 68 of whom tested positive for maternal cocaine use. From logistic multiple regression equations, weight and crown-heel length were significantly smaller in the maternal cocaine-use subset of this case-control study. Partial ankyloglossia, with a prevalence of 4.4 percent in the overall series, was significantly more common in males than in females (6.0% versus 2.3%), while race (black or white) had no influence on trait frequency. Controlling for race and sex, ankyloglossia was 3.5 times more likely to occur in the drug-use series, perhaps as a function of diminished mitotic rates.
Harris
E F
EF
Department of Orthodontics and Pediatric Dentistry, University of Tennessee, Memphis 38163.
Friend
G W
GW
Tolley
E A
EA
D000014:Abnormalities, Drug-Induced / Q000453:epidemiology*; D001741:Black or African American; D001724:Birth Weight / Q000187:drug effects; D001827:Body Height / Q000187:drug effects; D016022:Case-Control Studies; D003042:Cocaine / Q000009:adverse effects; D016578:Crack Cocaine / Q000009:adverse effects; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D016015:Logistic Models; D008297:Male; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D015995:Prevalence; D012044:Regression Analysis; D012307:Risk Factors; D012737:Sex Factors; D019966:Substance-Related Disorders / Q000150:complications*; D014059:Tongue / Q000002:abnormalities*; D044465:White People
D016578:Crack Cocaine; D003042:Cocaine