Cervical stenosis in pregnancy: a complication of cryotherapy in diethylstilbestrol-exposed women.
Cryotherapy causes a high incidence of cervical stenosis in diethylstilbestrol-exposed women because of an abnormal healing response. Consequently, the cervix may not dilate during labor, necessitating cesarean section. To prevent this, therapy should be localized to the abnormal tissue on the cervix instead of the entire transformation zone whenever possible.
Kalstone
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Department of Obstetrics and Gynecology, South Miami Hospital, FL.
D000328:Adult; D003251:Constriction, Pathologic / Q000209:etiology; D003452:Cryosurgery / Q000009:adverse effects*; D004054:Diethylstilbestrol / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007744:Obstetric Labor Complications / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology*; D002577:Uterine Cervical Diseases / Q000209:etiology*; D002583:Uterine Cervical Neoplasms / Q000139:chemically induced / Q000601:surgery*
D004054:Diethylstilbestrol