title: Nonimmune hydrops caused by massive fetomaternal hemorrhage and treated by intravascular transfusion.
abstract: Fetal hydrops at 26 weeks' gestation was diagnosed following a massive fetomaternal hemorrhage. Fetal intravascular transfusion was performed, and the hydrops completely resolved within 72 hours. The fetus required one more transfusion at 27 weeks' gestation. A subsequent percutaneous umbilical blood sampling at 30 weeks' gestation demonstrated a normal fetal hematocrit. A vaginal delivery at term resulted in a normal newborn. Massive fetomaternal hemorrhage is a well-known cause of nonimmune hydrops and may occur spontaneously in an otherwise normal pregnancy. Confirmation by percutaneous umbilical blood sampling and treatment by intravascular transfusion is recommended when massive fetomaternal hemorrhage causes hydrops in preterm gestations.
authors.affiliation: Department of Obstetrics and Gynecology, St. Lukes Hospital, Kansas City, Missouri.
authors.forename: J A
authors.initials: JA
authors.lastname: Thorp
authors.forename: G R
authors.initials: GR
authors.lastname: Cohen
authors.forename: J D
authors.initials: JD
authors.lastname: Yeast
authors.forename: D
authors.initials: D
authors.lastname: Perryman
authors.forename: C
authors.initials: C
authors.lastname: Welsh
authors.forename: N
authors.initials: N
authors.lastname: Honssinger
authors.forename: S
authors.initials: S
authors.lastname: Stephenson
authors.forename: J
authors.initials: J
authors.lastname: Hedrick
mesh_terms: D000328:Adult; D001805:Blood Transfusion, Intrauterine; D005260:Female; D005312:Fetal Blood / Q000166:cytology; D005331:Fetomaternal Transfusion / Q000150:complications*; D006400:Hematocrit; D006801:Humans; D015160:Hydrops Fetalis / Q000209:etiology* / Q000628:therapy; D011247:Pregnancy