title: Assignment of the human renal dipeptidase gene (DPEP1) to band q24 of chromosome 16.
abstract: Renal dipeptidase (DPEP1) or dehydropeptidase-I (E.C.3.4.13.11) is a kidney membrane enzyme which hydrolyzes a variety of dipeptides. DPEP1 is implicated in the renal metabolism of glutathione and its conjugates and is also responsible for hydrolysis of beta-lactam antibiotics. Using a human DPEP1 cDNA probe, we mapped the human renal dipeptidase gene to human chromosome 16 at band q24 by in situ hybridization.
authors.affiliation: Third Department of Medicine, Kyoto Prefectural University of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Nakagawa
authors.forename: J
authors.initials: J
authors.lastname: Inazawa
authors.forename: K
authors.initials: K
authors.lastname: Inoue
authors.forename: S
authors.initials: S
authors.lastname: Misawa
authors.forename: K
authors.initials: K
authors.lastname: Kashima
authors.forename: H
authors.initials: H
authors.lastname: Adachi
authors.forename: H
authors.initials: H
authors.lastname: Nakazato
authors.forename: T
authors.initials: T
authors.lastname: Abe
mesh_terms: D002871:Chromosome Banding; D002874:Chromosome Mapping; D002885:Chromosomes, Human, Pair 16; D015342:DNA Probes; D004150:Dipeptidases / Q000235:genetics*; D005260:Female; D058851:GPI-Linked Proteins; D006801:Humans; D007668:Kidney / Q000201:enzymology*
chemical_list: D015342:DNA Probes; D058851:GPI-Linked Proteins; D004150:Dipeptidases; C038937:dipeptidase; C549872:dipeptidase 1