title: Promotion as a factor in carcinogenesis.
abstract: Promotion is any factor which results in the increased cellular replication of initiated or transformed cells. We argue that cytotoxicity is not a necessary component of promotion and that, therefore, the existence of a threshold for promotion is unlikely.
authors.affiliation: Risk Analysis Section, Oak Ridge National Laboratory, TN 37831-6109.
authors.forename: C C
authors.initials: CC
authors.lastname: Travis
authors.forename: H
authors.initials: H
authors.lastname: Belefant
mesh_terms: D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D008938:Mitosis; D016296:Mutagenesis; D009369:Neoplasms / Q000139:chemically induced*