title: Association of t(15;17) and t(8;21) in the initial phase of an acute promyelocytic leukemia.
abstract: Two clones were observed at the initial phase of an acute myelogenous leukemia (AML): 46,XX,t(15;17) and 46,XX,t(8;21),t(15;17). Clinical, immunologic, and morphologic findings were in favor of expression of both chromosomal anomalies. Relapse occurred after 12 months of complete remission with typical acute promyelocytic leukemia (APL) syndrome when t(15;17) alone was then most predominant.
authors.affiliation: Laboratoire d'Hématologie et Cytogénétique, Hôpital Edouard Herriot, Lyon, France.
authors.forename: C
authors.initials: C
authors.lastname: Charrin
authors.forename: D
authors.initials: D
authors.lastname: Ritouet
authors.forename: L
authors.initials: L
authors.lastname: Campos
authors.forename: Y
authors.initials: Y
authors.lastname: Devaux
authors.forename: E
authors.initials: E
authors.lastname: Archimbaud
authors.forename: J
authors.initials: J
authors.lastname: Fraisse
authors.forename: D
authors.initials: D
authors.lastname: Fiere
authors.forename: D
authors.initials: D
authors.lastname: Germain
mesh_terms: D015703:Antigens, CD / Q000032:analysis; D001853:Bone Marrow / Q000473:pathology; D002884:Chromosomes, Human, Pair 15; D002886:Chromosomes, Human, Pair 17; D002891:Chromosomes, Human, Pair 21; D002898:Chromosomes, Human, Pair 8; D005260:Female; D006801:Humans; D007621:Karyotyping; D015473:Leukemia, Promyelocytic, Acute / Q000235:genetics* / Q000473:pathology; D008875:Middle Aged; D014178:Translocation, Genetic
chemical_list: D015703:Antigens, CD