title: A prospective survey of drug induced hepatotoxicity in a large hospital.
abstract: A prospective survey of laboratory records was carried out to identify the extent of drug induced hepatotoxicity in a hospital population. Eleven of 1000 (1.1%) abnormal liver function tests were due to drug induced hepatotoxicity. Anti-tubercular drugs, viz isoniazid, rifampicin and pyrazinamide were responsible for all cases of serious hepatotoxicity.
authors.affiliation: Department of Pharmacology, Seth G S Medical College, Parel, Bombay.
authors.forename: N A
authors.initials: NA
authors.lastname: Kshirsagar
authors.forename: S C
authors.initials: SC
authors.lastname: Karande
authors.forename: C N
authors.initials: CN
authors.lastname: Potkar
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies
chemical_list: D000995:Antitubercular Agents