[HDL cholesterol as a sensitive diagnostic parameter in malaria].
In patients with malaria the lipid parameters triglycerides, cholesterol, and HDL-cholesterol were determined routinely. At the time of admission hypertriglyceridemia, hypocholesterolemia, and an extreme decrease in HDL-cholesterol were found. This dyslipoproteinemia was present in cases of falciparum malaria, as well as in cases of benign tertian malaria. The extent of HDL-cholesterol decrease showed no correlation to the severity of the clinical course of disease. HDL-cholesterol has proven to be an independent diagnostic laboratory finding in cases of suspected malarial infection. This parameter displays high diagnostic sensitivity, but no specificity for malaria.
Kittl
E M
EM
Zentrallabor, Franz-Josef-Spitals, Wien.
Diridl
G
G
Lenhart
V
V
Neuwald
C
C
Tomasits
J
J
Pichler
H
H
Bauer
K
K
D000328:Adult; D000368:Aged; D001054:Apolipoproteins A / Q000378:metabolism; D002097:C-Reactive Protein / Q000378:metabolism; D008076:Cholesterol, HDL / Q000097:blood*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008288:Malaria / Q000097:blood* / Q000175:diagnosis*; D016778:Malaria, Falciparum / Q000097:blood / Q000175:diagnosis; D016780:Malaria, Vivax / Q000097:blood / Q000175:diagnosis; D008297:Male; D008875:Middle Aged
D001054:Apolipoproteins A; D008076:Cholesterol, HDL; D002097:C-Reactive Protein
HDL-Cholesterin als sensitiver Diagnoseparameter bei Malaria.