title: A randomized prospective study to assess the effect of the use of home urinary luteinizing hormone detection on the efficiency of donor insemination.
abstract: A study was carried out to establish whether the use of home urinary luteinizing hormone (LH) detection to predict ovulation could decrease the number of clinic visits required for the management of a donor insemination (DI) cycle, and thus optimize use of clinic resources without adversely affecting pregnancy rates. This was a randomized prospective study carried out at a donor insemination clinic in Oxford, England. Fifty-six patients participated in the trial; 27 used home urinary ovulation detection for a total of 111 cycles and 29 had a total of 123 DI cycles managed by routine clinical methods. There was a significant reduction in the number of visits per cycle (P less than 0.001) if home kits for detection of ovulation were used. There was no significant difference in the monthly fecundity or cumulative conception rates. We conclude that the use of home urinary LH detection in donor insemination can reduce patient attendance at the clinic and optimize the use of medical resources without adversely affecting pregnancy rates.
authors.affiliation: Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Headington, Oxford, UK.
authors.forename: J N
authors.initials: JN
authors.lastname: Robinson
authors.forename: G M
authors.initials: GM
authors.lastname: Lockwood
authors.forename: J D
authors.initials: JD
authors.lastname: Dalton
authors.forename: P A
authors.initials: PA
authors.lastname: Franklin
authors.forename: M M
authors.initials: MM
authors.lastname: Farr
authors.forename: D H
authors.initials: DH
authors.lastname: Barlow
mesh_terms: D005260:Female; D006801:Humans; D007315:Insemination, Artificial / Q000191:economics*; D007986:Luteinizing Hormone / Q000652:urine*; D010061:Ovulation Detection / Q000379:methods*; D011247:Pregnancy; D011446:Prospective Studies; D011897:Random Allocation; D011933:Reagent Kits, Diagnostic / Q000191:economics
chemical_list: D011933:Reagent Kits, Diagnostic; D007986:Luteinizing Hormone