SK&F 105685 suppresses allogeneically induced mononuclear and endothelial cell activation and cytokine production and prolongs rat cardiac allograft survival.
Hancock
W W
WW
Department of Pathology and Immunology, Monash Medical School, Alfred Hospital, Prahran, Victoria, Australia.
Schmidbauer
G
G
Badger
A M
AM
Kupiec-Weglinski
J W
JW
D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000818:Animals; D016207:Cytokines / Q000096:biosynthesis*; D004730:Endothelium, Vascular / Q000187:drug effects / Q000502:physiology*; D006084:Graft Rejection; D006085:Graft Survival; D016027:Heart Transplantation / Q000276:immunology / Q000473:pathology / Q000502:physiology*; D007963:Leukocytes, Mononuclear / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D011917:Rats, Inbred Lew; D011919:Rats, Inbred Strains; D013141:Spiro Compounds / Q000627:therapeutic use*; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D016042:Transplantation, Heterotopic; D014184:Transplantation, Homologous
D000276:Adjuvants, Immunologic; D016207:Cytokines; D013141:Spiro Compounds; C062162:SK&F 105685