title: Primary hepatic leiomyosarcoma in a child with the acquired immunodeficiency syndrome.
abstract: We report the first case of acquired immunodeficiency syndrome (AIDS)-related primary hepatic leiomyosarcoma in a 9-year-old girl. The pathologic diagnosis was made on a partial hepatectomy specimen and was confirmed by immunohistochemistry and electron microscopy. No human immunodeficiency virus-related nucleic acid was identified in tumor cells by in situ hybridization. Review of the AIDS-related literature reveals a rising incidence of tumors of smooth muscle origin in human immunodeficiency virus-infected patients. This case study details the eighth pediatric AIDS patient with a tumor of smooth muscle origin and represents the 20th and the youngest patient with primary hepatic leiomyosarcoma to be reported in the world literature.
authors.affiliation: Department of Pathology and Laboratory Medicine, Albany Medical College, NY 12208.
authors.forename: J S
authors.initials: JS
authors.lastname: Ross
authors.forename: A
authors.initials: A
authors.lastname: Del Rosario
authors.forename: H X
authors.initials: HX
authors.lastname: Bui
authors.forename: H
authors.initials: H
authors.lastname: Sonbati
authors.forename: O
authors.initials: O
authors.lastname: Solis
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D002648:Child; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000150:complications* / Q000473:pathology; D008113:Liver Neoplasms / Q000150:complications* / Q000473:pathology