A comparison of intraperitoneal prostheses for the repair of abdominal muscular wall defects in rats.
We compared the tissue response to the intraperitoneal implantation of three different prostheses (Gore-Tex, Mersilène, Vicryl-Mersilène) used to repair abdominal wall defects in rats. Vicryl-Mersilène is a new experimental prosthesis made of Dacron (Mersilène) coated with absorbable polyglactin (Vicryl). The least amount of adhesions to omentum and gut was found with Mersilène. Gore-Tex was responsible for the accumulation of neutrophils rather than macrophages mostly collected in close contact with Mersilène and Vicryl-Mersilène. Fibrosis, evaluated by histology and computerized morphometry, was mostly found with Vicryl-Mersilène. This should allow a better incorporation of Mersilène and a tighter anchorage to the abdominal wall, after Vicryl resorption.
Pans
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Department of Abdominal Surgery, University of Liège, Belgium.
Pierard
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GE
D000009:Abdominal Muscles / Q000601:surgery*; D000818:Animals; D005355:Fibrosis / Q000209:etiology; D005549:Foreign-Body Reaction / Q000473:pathology*; D011093:Polyethylene Terephthalates; D011098:Polyglactin 910; D011138:Polytetrafluoroethylene; D011183:Postoperative Complications; D051381:Rats; D011919:Rats, Inbred Strains; D013526:Surgical Mesh; D000267:Tissue Adhesions / Q000209:etiology
D011093:Polyethylene Terephthalates; D011098:Polyglactin 910; D011138:Polytetrafluoroethylene