title: Carotid artery stenosis: clinical efficacy of two-dimensional time-of-flight MR angiography.
abstract: To assess the clinical efficacy of two-dimensional time-of-flight magnetic resonance (MR) angiography in the evaluation of carotid artery stenosis, a group of patients was evaluated in which 73 vessels were studied with both MR and conventional angiography. Four experienced neuroradiologists each scored both the MR and conventional angiograms in a blinded manner by using a standardized scoring scheme. Comparison of the scores revealed a high degree of correlation. In particular, MR angiography served to discriminate reliably between mildly narrowed and severely narrowed or occluded vessels. Furthermore, severe stenoses were accurately discriminated from occlusions in all cases. MR angiography is a robust and accurate modality for the characterization of carotid artery stenosis. It is useful in conjunction with routine MR imaging of the brain in the evaluation of the patient with suspected carotid arterial disease.
authors.affiliation: Barrow Neurological Institute, St Joseph's Hospital and Medical Center, Phoenix, AZ 85013.
authors.forename: J E
authors.initials: JE
authors.lastname: Heiserman
authors.forename: B P
authors.initials: BP
authors.lastname: Drayer
authors.forename: E K
authors.initials: EK
authors.lastname: Fram
authors.forename: P J
authors.initials: PJ
authors.lastname: Keller
authors.forename: C R
authors.initials: CR
authors.lastname: Bird
authors.forename: J A
authors.initials: JA
authors.lastname: Hodak
authors.forename: R A
authors.initials: RA
authors.lastname: Flom
mesh_terms: D002339:Carotid Arteries / Q000473:pathology*; D016893:Carotid Stenosis / Q000175:diagnosis* / Q000453:epidemiology; D002533:Cerebral Angiography; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D012372:ROC Curve; D012680:Sensitivity and Specificity