Brain metastases of endometrial carcinoma. Case report and review of literature.
Distant metastases, and especially brain metastases, are a rare event in the course of a patient with an endometrial carcinoma. The case of Mrs. L. v. O., who died 22 months after primary treatment, of a histologically proven central nervous system metastasis, prompted us to review our material as well as the literature. We found in our data on 2,293 patients treated between 1965 and 1988 only four patients with histologically proven brain metastases whereas another seven presented with manifest clinical signs of central nervous system involvement. These eleven patients constitute 0.48% of our material; the incidence reported in general is with 0.8 to 1.4% somewhat higher.
De Porre
P M
PM
Department of Radiation Oncology, Dr. Daniel den Hoed Cancer Center, Rotterdam, The Netherlands.
Subandono Tjokrowardojo
A J
AJ
D000230:Adenocarcinoma / Q000453:epidemiology / Q000556:secondary*; D000368:Aged; D001932:Brain Neoplasms / Q000453:epidemiology / Q000556:secondary*; D005260:Female; D006801:Humans; D009426:Netherlands / Q000453:epidemiology; D012189:Retrospective Studies; D014594:Uterine Neoplasms / Q000453:epidemiology