Interstitial 9q deletion. A primary change in a case with splenomegaly of unknown origin.
In a case with splenomegaly of unknown origin and features of hypersplenism, an interstitial 9q deletion was identified as a sole clonal abnormality of bone marrow cells. The meaning of 9q deletion as a primary change, as well as its clinical significance, are considered.
Ferti
A
A
5th Medical Department, Evangelismos Hospital, Athens, Greece.
Tsikritzi
H
H
Yialamboukides
M
M
Economopoulos
T
T
Panani
A
A
Lyberatos
C
C
D000368:Aged; D001803:Blood Transfusion; D001853:Bone Marrow / Q000473:pathology*; D002871:Chromosome Banding; D002872:Chromosome Deletion; D002899:Chromosomes, Human, Pair 9; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007621:Karyotyping; D013156:Splenectomy; D013163:Splenomegaly / Q000235:genetics* / Q000473:pathology / Q000628:therapy