Effect of sodium valproate on the secretion of prolactin, cortisol and growth hormone in migraine patients.
A single oral dose of 500 mg sodium valproate had no effect on prolactin, growth hormone and cortisol secretion in 10 migraine patients when compared with five healthy controls and four migraine patients receiving placebo. Basal values of prolactin (PRL), cortisol and growth hormone (GH) were within the normal range, though PRL basal levels were lower in three patients (21.5%) in the migraine group.
Hering
R
R
Department of Neurology, Beilinson Medical Center, Petach Tikva, Israel.
Gilad
I
I
Laron
Z
Z
Kuritzky
A
A
D000328:Adult; D005260:Female; D013006:Growth Hormone / Q000097:blood / Q000378:metabolism*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000097:blood / Q000145:classification / Q000378:metabolism*; D011388:Prolactin / Q000097:blood / Q000378:metabolism*; D013997:Time Factors; D014635:Valproic Acid / Q000494:pharmacology*
D014635:Valproic Acid; D011388:Prolactin; D013006:Growth Hormone; D006854:Hydrocortisone