Chromosome partitioning in Escherichia coli in the absence of dam-directed methylation.
Escherichia coli dam mutants, lacking the GATC DNA methylase, do not produce anucleate cells at high frequencies, suggesting that hemimethylation of the chromosome origin of replication, oriC, is not essential for correct chromosome partitioning.
Vinella
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Institut Jacques Monod, Centre National de la Recherche Scientifique, Université Paris, France.
Jaffé
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D'Ari
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Kohiyama
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Hughes
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D004261:DNA Replication; D004269:DNA, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics*; D029968:Escherichia coli Proteins; D008745:Methylation; D008780:Methyltransferases / Q000378:metabolism; D015265:Site-Specific DNA-Methyltransferase (Adenine-Specific)
D004269:DNA, Bacterial; D029968:Escherichia coli Proteins; D008780:Methyltransferases; C058693:Dam methyltransferase; D015265:Site-Specific DNA-Methyltransferase (Adenine-Specific); C499294:dam protein, E coli