[Effect of HMG proteins and their phosphorylated forms on the process of transcription in neuronal nuclei of the rat brain (data from an immunochemical analysis)].
It was found that chromatin transcription in the neuronal nucleus of rat brain is inhibited by antisera to proteins HMG 14, HMG 17 and HMG 2. It is known that chromatin transcription of the neuronal nucleus and phosphorylation of chromosomal proteins are activated by etimizol. The phosphorylation of chromosomal proteins activated by etimizol is inhibited by the antiserum to HMG 14 (but not to HMG 17). The data obtained are suggestive of a possible role of HMG proteins and their phosphorylated forms in the regulation of transcription.
Beliavtseva
L M
LM
Kozlov
S V
SV
Kulikova
O G
OG
Surkova
E A
EA
Fedorova
N A
NA
D000818:Animals; D001921:Brain / Q000166:cytology* / Q000378:metabolism; D002417:Cattle; D002467:Cell Nucleus / Q000378:metabolism*; D004591:Electrophoresis, Polyacrylamide Gel; D005042:Etimizol / Q000494:pharmacology; D006609:High Mobility Group Proteins / Q000378:metabolism*; D007106:Immune Sera; D007150:Immunohistochemistry; D009474:Neurons / Q000378:metabolism*; D010766:Phosphorylation / Q000187:drug effects; D051381:Rats; D014158:Transcription, Genetic
D006609:High Mobility Group Proteins; D007106:Immune Sera; D005042:Etimizol
Vliianie belkov HMG i ikh fosforilirovannykh form na protsess transkriptsii i neĭronal'nykh iadrakh golovnogo mozga krys (dannye immunokhimicheskogo analiza)