title: Accumulation of iron oxide particles around liver metastases during MR imaging.
abstract: The histologic nature of the bright ring ("peritumoral edema") around some liver metastases on T2-weighted magnetic resonance (MR) images is controversial. In the case reported, particles of the iron oxide contrast agent AMI-25 are retained in the peritumoral zone of a colon cancer metastasis, causing the bright ring to disappear. The location of iron particles in resected specimens could be used systematically to study peritumoral edema.
authors.affiliation: Department of Radiology, Massachusetts General Hospital, Boston 02114.
authors.forename: P F
authors.initials: PF
authors.lastname: Hahn
authors.forename: D D
authors.initials: DD
authors.lastname: Stark
authors.forename: J T
authors.initials: JT
authors.lastname: Ferrucci
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000556:secondary*; D015179:Colorectal Neoplasms / Q000473:pathology; D003287:Contrast Media; D003911:Dextrans; D052203:Ferrosoferric Oxide; D006801:Humans; D007501:Iron; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000175:diagnosis / Q000556:secondary*; D008279:Magnetic Resonance Imaging; D058185:Magnetite Nanoparticles; D008297:Male; D008875:Middle Aged; D010087:Oxides
chemical_list: D003287:Contrast Media; D003911:Dextrans; D058185:Magnetite Nanoparticles; D010087:Oxides; D007501:Iron; C065507:ferumoxides; D052203:Ferrosoferric Oxide