Influence of the distance between interrupted sutures and the tension of sutures on the healing of experimental colonic anastomoses.
Certain technical factors determine the success of the creation of intestinal anastomoses. The influence of the distance between interrupted sutures and the suture tension on wound healing was investigated in an experimental study using a specially designed suture model. The combination of a long suture distance (group A, 2.5 mm) and a short suture distance (group B, 1.5 mm) with three different suture tensions, i.e., (1) no tension; (2) moderate tension; and (3) high tension, resulted in six different techniques. Tension was created by means of a spring balance. The anastomoses were examined macroscopically, histologically by microangiography, and by bursting pressure. Apposition of the bowel wall between the interrupted sutures was inappropriate due to prolapse of the mucosa in 7.9% of the patients in group A but did not occur in groups B2 and B3. The leakage rate was 4.6% in group A and 1.3% in group B. Early healing of the mucosa was noted in group B2. Bursting pressure was significantly higher on day 2 and 4 in groups B2 and B3. The results demonstrate the influence of suture technique on the wound healing of intestinal anastomoses. The best healing pattern was achieved by a small distance between the sutures and a moderate suture tension.
Waninger
J
J
Chirurgische Universitätsklinik Freiburg, Germany.
Kauffmann
G W
GW
Shah
I A
IA
Farthmann
E H
EH
D000714:Anastomosis, Surgical; D000792:Angiography; D000818:Animals; D003106:Colon / Q000098:blood supply / Q000473:pathology / Q000601:surgery*; D008297:Male; D008852:Microradiography; D051381:Rats; D011919:Rats, Inbred Strains; D013536:Suture Techniques; D013718:Tensile Strength; D014945:Wound Healing