title: [Diagnostic problems in local recurrence after breast saving treatment].
abstract: 353 patients with stages pTis, pT1-2, pN0-1, cM0 breast cancer have been treated consecutively by breast conserving therapy in a prospective, nonrandomized study at the University Hospital Basel and the Women's Clinic Rheinfelden/Baden/Germany. The median age was 47 years, the median follow-up time 67 months, and 4% only of this collective were lost to follow-up after a median time of 42 months. In 79% of the cases the tumor was excised totally, while in 19% the resection margins were positive and in 2% only the margins were not available for histological judgement. The rate of local failure reached 8% with a median time interval of 53 months. 116 patients showed postactinic induration in the primary tumor region. 73 of these were given additional diagnostic examination: The postactinic induration was judget clinically suspicious in 51 cases and clinically nonsuspicious of local failure in 22 cases. All 73 patients received additional examination by mammography and biopsy. By comparison with the histological results the clinical results were correct in 59% and false in 41%, while the mammographic results were correct in 82% and false in 18% of the cases.
authors.affiliation: Institut für Radio-Onkologie, Universitätskliniken Basel.
authors.forename: E
authors.initials: E
authors.lastname: Walther
authors.forename: R
authors.initials: R
authors.lastname: Hünig
authors.forename: F
authors.initials: F
authors.lastname: Harder
authors.forename: U
authors.initials: U
authors.lastname: Laffer
authors.forename: A C
authors.initials: AC
authors.lastname: Almendral
authors.forename: H
authors.initials: H
authors.lastname: Dieterich
authors.forename: J P
authors.initials: JP
authors.lastname: Obrecht
authors.forename: J
authors.initials: J
authors.lastname: Torhorst
authors.forename: J
authors.initials: J
authors.lastname: Roth
mesh_terms: D001706:Biopsy; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008327:Mammography; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000473:pathology; D009367:Neoplasm Staging
vernacular_title: Diagnostische Probleme beim Lokalrezidiv nach brusterhaltender Behandlung.