Aspirin use and survival after coronary bypass surgery.
From Jan. 1, 1968, through Dec. 31, 1981, 5618 patients in a single cardiovascular surgery practice underwent coronary bypass surgery. Detailed clinical information was obtained during hospitalization and entered into a data base. All surviving patients were surveyed for aspirin use four times: in 1984, 1985, 1986, and 1987. A subgroup of 2395 patients gave consistent answers on every returned survey. The group that answered consistently "yes" had a 5-year survival rate of 79%; those who answered consistently "no" had a 5-year survival rate of 67%. Stepwise logistic regression showed that, after adjusting for patient characteristics, the relative risk of death was 58% (confidence interval 47% to 70%) for consistent aspirin users compared with consistent non-aspirin users. This study provides evidence that regular aspirin use after bypass surgery may enhance survival.
Johnson
W D
WD
Department of Cardiovascular Diseases, St. Mary's Hospital, Milwaukee, WI.
Kayser
K L
KL
Hartz
A J
AJ
Saedi
S F
SF
D000206:Actuarial Analysis; D001241:Aspirin / Q000627:therapeutic use*; D001026:Coronary Artery Bypass / Q000401:mortality*; D003625:Data Collection; D016208:Databases, Factual; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D016019:Survival Analysis; D015996:Survival Rate; D014922:Wisconsin / Q000453:epidemiology
D001241:Aspirin