The value of technetium-99M renography for the detection of renal artery stenosis in patients with aortic and lower limb vascular disease.
The results of technetium renography were compared with arteriography to determine whether this is a satisfactory screening test for renal artery stenosis (RAS). Sixty-three patients were studied before aortic surgery. All were investigated by aortography and isotope renography. These tests were assessed blind and all arteriograms were graded by a single independent radiologist. Renal artery stenosis was detected by arteriography in 34 (54%) patients. Twenty-three (37%) had mild (less than 50%) stenosis, seven (11%) had moderate (50-80%) stenosis and four (6%) had severe (greater than 80%) stenosis. Of these 34 patients, only 6 (18%) were correctly diagnosed by isotope renography. None of the four with severe stenosis were identified. Isotope renography resulted in six true positives, six false positives, 23 true negatives and 28 false negatives. It was concluded that isotope renography did not fulfil the criteria for a screening test for the detection of RAS and appeared to be of no value in those patients undergoing aortic surgery in whom arteriography was not indicated.
Judge
J S
JS
Department of Surgery, Sir Charles Gairdner Hospital, Nedlands, Western Australia.
Low
V
V
Gajraj
H
H
House
A K
AK
D000368:Aged; D001012:Aorta, Abdominal; D001014:Aortic Aneurysm / Q000150:complications*; D001027:Aortography; D001161:Arteriosclerosis / Q000150:complications; D006801:Humans; D007383:Intermittent Claudication / Q000150:complications*; D011237:Predictive Value of Tests; D011866:Radioisotope Renography; D012078:Renal Artery Obstruction / Q000000981:diagnostic imaging*; D016284:Technetium Tc 99m Pentetate
D016284:Technetium Tc 99m Pentetate