[Tumor diseases in families of 600 breast cancer patients with special reference to familial adenocarcinomatosis and the Li-Fraumeni-/SBLA syndrome].
In some families breast cancer aggregates as the predominant site-specific neoplasia and in others in association with defined malignancies. In the case of familial adenocarcinomatous (Lynch II-syndrome) it occurs together mainly with colorectal and endometrial carcinoma whereas in the case of the Li-Fraumeni/SBLA-syndrome it belongs to a wider spectrum including sarcoma, brain tumors, lung and laryngeal cancer, leukaemia and adrenocortical carcinoma. The occurrence of these malignancies is reported as they were observed in the families of 600 women suffering from breast cancer.
Müller
H
H
Departement Forschung, Basler Universitäts-kliniken, Kantonsspital Basel.
Mosimann
S
S
Gebhardt
M
M
Scott
R
R
Spycher
M
M
Weber
W
W
D000230:Adenocarcinoma / Q000235:genetics*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000235:genetics*; D005260:Female; D006801:Humans; D016864:Li-Fraumeni Syndrome / Q000235:genetics*; D008875:Middle Aged; D009386:Neoplastic Syndromes, Hereditary / Q000235:genetics*; D012307:Risk Factors
Tumorkrankheiten in den Familien von 600 Mammakarzinom-Patientinnen unter besonderer Berücksichtigung der familiären Adenokarzinomatose und des Li-Fraumeni-/SBLA-Syndroms.