title: Body space measurements in the hyponatraemia of carcinoma of the bronchus: evidence for the chronic 'sick cell' syndrome?
abstract: Body space measurements using simultaneous multiple isotope dilution techniques were made in both hyponatraemic and normonatraemic patients with carcinoma of the bronchus and wasting, and compared with those in a group of normal volunteers. Both groups of patients showed osmolal loss from cells. The significance of these findings in relation to the development of hyponatraemia is discussed.
authors.affiliation: Department of Chemical Pathology, Worthing Hospital, UK.
authors.forename: H J
authors.initials: HJ
authors.lastname: Southgate
authors.forename: B J
authors.initials: BJ
authors.lastname: Burke
authors.forename: G
authors.initials: G
authors.lastname: Walters
mesh_terms: D000328:Adult; D000368:Aged; D001834:Body Water / Q000378:metabolism; D002283:Carcinoma, Bronchogenic / Q000097:blood*; D005110:Extracellular Space / Q000378:metabolism*; D006801:Humans; D007010:Hyponatremia / Q000097:blood*; D007177:Inappropriate ADH Syndrome / Q000378:metabolism; D008175:Lung Neoplasms / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011188:Potassium / Q000097:blood; D012964:Sodium / Q000378:metabolism; D015431:Weight Loss
chemical_list: D012964:Sodium; D011188:Potassium