Thrombogenicity of gelatine impregnated vascular grafts--an experimental study.
Acute platelet deposition on a knitted Dacron graft impregnated with gelatine to confer zero porosity was compared to a standard knitted Dacron graft. The accumulation of platelets was assessed by reinfusion of 111In labelled platelets and imaging with a scintillation camera. The accumulation of platelets was significantly higher on the sealed grafts at the beginning of the experiments but a steady-state was rapidly achieved and no differences was observed regarding the patency.
Pärsson
H
H
Department of Surgery, Lund University, Sweden.
Jawien
A
A
Norgren
L
L
Thörne
J
J
D000818:Animals; D001807:Blood Vessel Prosthesis; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000601:surgery; D005780:Gelatin; D006083:Graft Occlusion, Vascular / Q000000981:diagnostic imaging; D010974:Platelet Aggregation / Q000502:physiology; D011093:Polyethylene Terephthalates; D011474:Prosthesis Design; D011877:Radionuclide Imaging; D013499:Surface Properties; D013552:Swine
D011093:Polyethylene Terephthalates; D005780:Gelatin