title: Seronegative systemic lupus erythematosus.
abstract: We have presented a patient with severe clinical SLE but negative serological tests. This diagnostic difficulty, together with a presentation limited to the skin and an initial response to high dose steroids probably lead to a delay in starting immunosuppression. The finding of a retinopathy was important in deciding on therapy. An excellent response to immunosuppression was seen, with full recovery.
authors.affiliation: University Department of Medicine, Bristol Royal Infirmary.
authors.forename: P
authors.initials: P
authors.lastname: Creamer
authors.forename: J
authors.initials: J
authors.lastname: Kirwan
mesh_terms: D000328:Adult; D003872:Dermatitis / Q000150:complications; D005654:Fundus Oculi; D006801:Humans; D007165:Immunosuppression Therapy; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D012164:Retinal Diseases / Q000150:complications / Q000175:diagnosis; D012698:Serologic Tests; D013256:Steroids / Q000627:therapeutic use
chemical_list: D013256:Steroids