Four new cycloartane saponins from Curculigo orchioides.
Four new cycloartane-type triterpene glycosides named curculigosaponins G, H, I, and J have been isolated from rhizomes of Curculigo orchioides (Chinese Name: Xiao Mao; Hypoxidaceae). Their structures were elucidated by FAB-MS, 1H-, 13C-NMR, and 2D-NMR analysis and chemical evidence. A pharmacological study showed that curculigosaponin G increased the weight of the thymus in vivo in mice.
Xu
J P
JP
Shanghai Institute of Materia Medica, Academia Sinica, Shanghai, People's Republic of China.
Xu
R S
RS
Li
X Y
XY
D000818:Animals; D002240:Carbohydrate Sequence; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008813:Mice, Inbred ICR; D008969:Molecular Sequence Data; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D013950:Thymus Gland / Q000187:drug effects
D004365:Drugs, Chinese Herbal; D012503:Saponins