title: Aspiration cytology in the diagnosis of malignant tumors in children.
abstract: On the basis of 65 fine-needle aspiration biopsies (FNAB) the efficiency of aspiration cytology combined with immunocytochemistry in preoperative diagnosis of malignant tumors in children was evaluated. All FNAB were performed under ultrasound or fluoroscopy guidance. There were no false-positive diagnoses. Morphological type of the tumor was properly diagnosed preoperatively in 50 patients. In 10 aspirates, the tumor type could not be diagnosed on the basis of light microscopy and immunocytochemistry. Due to technical reasons, five false-negative diagnoses (7.7%) were made. This study showed that FNAB is a safe, rapid, and effective method, which enables preoperative diagnosis of children's tumors in most cases.
authors.affiliation: Department of Tumor Pathology, Medical Academy, Szczecin, Poland.
authors.forename: W
authors.initials: W
authors.lastname: Gorczyca
authors.forename: E
authors.initials: E
authors.lastname: Bedner
authors.forename: P
authors.initials: P
authors.lastname: Juszkiewicz
authors.forename: M
authors.initials: M
authors.lastname: Chosia
mesh_terms: D000293:Adolescent; D000465:Algorithms; D014408:Biomarkers, Tumor / Q000032:analysis; D001707:Biopsy, Needle; D002648:Child; D002675:Child, Preschool; D005069:Evaluation Studies as Topic; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008297:Male; D009363:Neoplasm Proteins / Q000032:analysis; D009369:Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D011300:Preoperative Care
chemical_list: D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins