title: Dental findings of patients who underwent liver transplantation.
abstract: Cyclosporin-induced gingival enlargement was presented. Enlargement was noted at several sites in the mouth of five patients taking Cyclosporin following liver transplantation. Papillary gingival enlargement was observed to affect the entire maxilla and mandible. Enlargement was particularly marked in the interdental papillary region on the labial side of the anterior teeth of the maxilla. Discoloration of the teeth was observed. Radiographic findings were unremarkable. Oral management of these patients is the prevention of dental caries and infection originating in the area of gingival enlargement. It is important to begin proper brushing as early as possible for suppressing progression of gingival enlargement. For prevention of dental caries, prophylaxis is more important in the case of liver transplantation than with normal patients. It should be stressed to the patients or their parents that periodic examination, topical application of fluoride and pit and fissure sealants are of special importance.
authors.affiliation: Kobe Children's Hospital, Osaka Dental University.
authors.forename: Y
authors.initials: Y
authors.lastname: Funakoshi
authors.forename: C
authors.initials: C
authors.lastname: Ohshita
authors.forename: Y
authors.initials: Y
authors.lastname: Moritani
authors.forename: T
authors.initials: T
authors.lastname: Hieda
mesh_terms: D002675:Child, Preschool; D016572:Cyclosporine / Q000009:adverse effects*; D003774:Dental Plaque Index; D005260:Female; D005886:Gingival Hypertrophy / Q000139:chemically induced*; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects; D008297:Male; D009911:Oral Hygiene Index; D014075:Tooth Discoloration / Q000139:chemically induced
chemical_list: D016572:Cyclosporine