title: Polylactide screws in the fixation of olecranon osteotomies. A mechanical study in sheep.
abstract: We studied absorbable self-reinforced poly-L-lactide screws in the fixation of osteotomies in sheep. A left olecranon osteotomy in 10 sheep was fixed with polylactide screws and in an additional 10 sheep with metallic AO cortical screws. Follow-up times were 6 and 12 weeks. 8 polylactide fixations healed and 2 failed. All metal fixations united; one of them had a fracture of the proximal fragment resulting in malposition. After killing the sheep the olecranons were radiographed and the shear strengths of the osteotomies were compared with those of the non-operated contralateral bones. After 6 weeks the mean comparative strength was 74 percent in the polylactide group and 83 percent in the metallic control group. After 12 weeks the corresponding values were 112 and 47 percent (P less than 0.05). Our study demonstrated that the mechanical weakening of fixed bone can be avoided by using absorbable polylactide screws instead of metallic screws. However, polylactide screws are not recommended for use without external support in places of high mechanical strain.
authors.affiliation: Department of Orthopedics and Traumatology, University Central Hospital, Helsinki, Finland.
authors.forename: M J
authors.initials: MJ
authors.lastname: Manninen
authors.forename: U
authors.initials: U
authors.lastname: Päivärinta
authors.forename: R
authors.initials: R
authors.lastname: Taurio
authors.forename: P
authors.initials: P
authors.lastname: Törmälä
authors.forename: R
authors.initials: R
authors.lastname: Suuronen
authors.forename: J
authors.initials: J
authors.lastname: Räihä
authors.forename: P
authors.initials: P
authors.lastname: Rokkanen
authors.forename: H
authors.initials: H
authors.lastname: Pätiälä
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D001863:Bone Screws; D005260:Female; D005500:Follow-Up Studies; D008297:Male; D010027:Osteotomy / Q000295:instrumentation / Q000379:methods*; D011091:Polyesters; D011859:Radiography; D012756:Sheep; D014457:Ulna / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*
chemical_list: D011091:Polyesters; C033616:poly(lactide)