title: Effects of estradiol 17 beta implants on hematologic values and the chemiluminescence response of neutrophils of steers.
abstract: The effects of subcutaneous administration of a commercially available estradiol 17 beta implant on hematologic values and the chemiluminescence response of neutrophils were evaluated in 14 steers. Chemiluminescence and hematologic values were measured in treated (n = 8) and nontreated (n = 6) steers on days -14, -7, and -1 prior to implantation. Estradiol 17B was implanted into the treated group of steers on day 0, and blood samples were obtained from all steers on days 1, 2, 3, 4, 8, 15, 22, 29, 36, 43, and 50. The concentration of estrogen in serum was significantly (P = 0.0120) higher following implantation. Chemiluminescence and hematologic indices were not significantly affected by either implant status or serum concentrations of estrogen. The results of this study suggested that the use of implants containing estradiol 17 beta for promotion of weight gain in steers will not result in alterations of hematologic values or the neutrophil respiratory burst.
authors.affiliation: Department of Large Animal Surgery and Medicine College of Veterinary Medicine, Auburn University, Al 36849-5522.
authors.forename: K L
authors.initials: KL
authors.lastname: Angel
authors.forename: J
authors.initials: J
authors.lastname: Schumacher
authors.forename: D F
authors.initials: DF
authors.lastname: Wolfe
authors.forename: P H
authors.initials: PH
authors.lastname: Klesius
authors.forename: J W
authors.initials: JW
authors.lastname: Tyler
authors.forename: R L
authors.initials: RL
authors.lastname: Carson
mesh_terms: D000818:Animals; D002417:Cattle / Q000097:blood* / Q000276:immunology; D004343:Drug Implants; D004906:Erythrocyte Count / Q000662:veterinary; D004958:Estradiol / Q000008:administration & dosage / Q000494:pharmacology*; D004967:Estrogens / Q000097:blood; D006400:Hematocrit / Q000662:veterinary; D006454:Hemoglobins / Q000032:analysis; D007958:Leukocyte Count / Q000662:veterinary; D008297:Male; D009504:Neutrophils / Q000187:drug effects* / Q000276:immunology; D012044:Regression Analysis; D016897:Respiratory Burst / Q000187:drug effects*; D015430:Weight Gain / Q000187:drug effects
chemical_list: D004343:Drug Implants; D004967:Estrogens; D006454:Hemoglobins; D004958:Estradiol