Ordered binding model as a general mechanistic mechanism for secondary active transport systems.
The mechanistic mechanism of secondary active transport processes has not been fully elucidated. Based on substrate binding studies dependent on coupling cation concentrations of the glutamate, melibiose, lactose and proline transport carriers in Escherichia coli, the ordered binding mechanism was proposed as the energy coupling mechanism of the transport systems. This ordered binding mechanism satisfactorily explained the properties of the secondary active transport systems. Thus, this mechanism as the general energy coupling mechanism for the transport systems is discussed.
Yamato
I
I
Department of Biological Science and Technology, Science University of Tokyo, Chiba, Japan.
D001426:Bacterial Proteins; D001693:Biological Transport, Active; D002352:Carrier Proteins; D008958:Models, Molecular; D011485:Protein Binding
D001426:Bacterial Proteins; D002352:Carrier Proteins