title: Sutureless anastomosis of blood vessels using cyanoacrylate adhesives.
abstract: On the assumption that the remaining suture threads of the anastomotic line play an important role in the progression of anastomotic neointimal hyperplasia, we performed an experimental study on the sutureless anastomosis of blood vessels. An expanded polytetrafluoroethylene graft, 5 mm in diameter and 2 cm in length, was implanted on the abdominal aorta of mongrel adult using one of three methods of anastomosis, namely; a continuous suture, a stay suture, or sutureless anastomosis. Overall patency rates were 83.3 per cent, 91.7 per cent and 75.0 per cent respectively. The thickness of the pannus in the distal anastomotic line after 12 months was 107 microns in one graft in the continuous suture group, 106 microns and 222 microns in 2 grafts each in the stay suture group, and 41 microns and 117 microns in 2 grafts each in the sutureless group. Because there were cases of patency even after 12 months with a very small pannus thickness, sutureless anastomosis is considered to be a useful method of preventing anastomotic neointimal hyperplasia.
authors.affiliation: First Department of Surgery, Yamaguchi University School of Medicine, Ube, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Takenaka
authors.forename: K
authors.initials: K
authors.lastname: Esato
authors.forename: M
authors.initials: M
authors.lastname: Ohara
authors.forename: N
authors.initials: N
authors.lastname: Zempo
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D001807:Blood Vessel Prosthesis; D001808:Blood Vessels / Q000473:pathology; D003487:Cyanoacrylates / Q000627:therapeutic use*; D004285:Dogs; D013537:Sutures; D014014:Tissue Adhesives / Q000627:therapeutic use*; D014654:Vascular Patency; D014656:Vascular Surgical Procedures / Q000379:methods*
chemical_list: D003487:Cyanoacrylates; D014014:Tissue Adhesives