[Cytomorphologic assessment of the effect of Bacillus intermedius RNase on the organs of experimental animals].
Cytomorphological changes in the organs of laboratory animals after their treatment with RNAse from Bacillus intermedius were investigated. It was shown that the effect of RNAse on the thymus and spleen was evident from stimulation of the elements of the lympho and hemopoiesis while its effect on the liver manifested itself in increased stromal response of the liver and higher functional activity of the organ. The observed effects did not depend on catalytic activity of the enzyme.
Kurinenko
B M
BM
Nekhoroshkova
Z M
ZM
Khusnullina
K T
KT
Sobchuk
L I
LI
Karpova
S I
SI
Bulgakova
R Sh
RSh
D000818:Animals; D001407:Bacillus / Q000201:enzymology*; D006410:Hematopoiesis / Q000187:drug effects; D008099:Liver / Q000187:drug effects; D008297:Male; D051379:Mice; D012260:Ribonucleases / Q000494:pharmacology*; D013154:Spleen / Q000187:drug effects; D013950:Thymus Gland / Q000187:drug effects; D014781:Viscera / Q000166:cytology / Q000187:drug effects*
D012260:Ribonucleases
Tsitomorfologicheskaia otsenka vliianiia RNKazy Bacillus intermedius na organy éksperimental'nykh zhivotnykh.