[Growth velocity in thalassemic children receiving different protocols of chelating therapy].
The aim of this study was to compare growth velocity in thalassemic children using two different treatment protocols. Thalassemic children were initially treated with high daily doses of desferrioxamine, obtaining a good rate of initial growth which then unexpectedly slowed down later. The introduction of a new treatment protocol reducing both the dose and frequency with which the drug was administered provoked a significant increase in the rate of growth greater than that observed in the group treated using the previous protocol.
Elena
M G
MG
Centro di Auxopatologia Infantile, Università di Torino.
Fedele
A
A
Gianino
P
P
Giordanino
S
S
Murru
P
P
Tosi
C
C
Vannelli
S
S
D015913:Chelation Therapy; D002648:Child; D002675:Child, Preschool; D003676:Deferoxamine / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D006128:Growth / Q000187:drug effects*; D006801:Humans; D008297:Male; D013789:Thalassemia / Q000503:physiopathology* / Q000628:therapy*
D003676:Deferoxamine
Velocità di crescita dei bambini talassemici sottoposti a diversi protocolli di terapia chelante.