title: [Morbidity and results of 100 radical hysterectomies performed in an oncology center].
abstract: One hundred consecutive radical hysterectomies performed in a Dutch oncology centre during a five and a half year period between 1984 and 1990, were analysed. The operations were performed in a uniform manner by the same three surgeons. Surgical mortality was nil. Mean operating time was 4 hours and mean blood loss amounted to 1200 ml. One patient developed a vesicovaginal fistula. Long lasting urinary symptoms occurred in 32% of patients, sex problems in 13%. The latter situation was encountered significantly more frequently when surgery was combined with radiotherapy. Eighty-two of the 100 patients had a primary cervical carcinoma and were analysed further. Distribution according to stage was as follows: stage IA: 3, IB: 64, IIA: 13, IIB: 2. Postoperative external and intracavitary pelvic radiation was given in 34 patients (41%). Three-year survival of these patients amounted to 86%. One-third of patients had a large primary tumour (diameter greater than 4 cm). Three-year survival rate in this subgroup of patients was 78%. Lymph node metastases were found in 14 patients (17%). Three-year survival rates for patients with and without lymph node metastases were 64% and 94%, respectively (p less than 0.0001). Results and complications of this series were compared with the current literature data and found to be comparable and sometimes even better than recent literature data. These findings may serve to advocate further centralisation of this kind of surgery in oncological centres in the Netherlands.
authors.affiliation: Afd. Gynaecologie, Academisch Ziekenhuis, Leiden.
authors.forename: J B
authors.initials: JB
authors.lastname: Trimbos
authors.forename: B
authors.initials: B
authors.lastname: Adema
authors.forename: A A
authors.initials: AA
authors.lastname: Peters
authors.forename: G G
authors.initials: GG
authors.lastname: Kenter
authors.forename: A
authors.initials: A
authors.lastname: Snijders-Keilholz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002173:Cancer Care Facilities; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D009426:Netherlands; D011183:Postoperative Complications / Q000209:etiology; D012189:Retrospective Studies; D012735:Sexual Dysfunction, Physiological / Q000209:etiology; D016019:Survival Analysis; D014570:Urologic Diseases / Q000209:etiology; D002583:Uterine Cervical Neoplasms / Q000601:surgery; D014594:Uterine Neoplasms / Q000601:surgery*
vernacular_title: Morbiditeit en resultaten van 100 radicale hysterectomieën verricht in een oncologisch centrum.