Effect of dipyridamole and adenosine monophosphate on cell proliferation in the hemopoietic tissue of normal and gamma-irradiated mice.
Combined treatment with dipyridamole and adenosine monophosphate enhances cell proliferation in the hemopoietic tissue of normal and gamma-irradiated mice. This effect can be explained by the elevation of extracellular adenosine, and the receptor-mediated activation of the cell adenylate cyclase system.
Pospísil
M
M
Institute of Biophysics, Czechoslovak Academy of Sciences, Brno.
Hofer
M
M
Netíková
J
J
Viklická
S
S
Pipalová
I
I
Bartonícková
A
A
D000241:Adenosine / Q000502:physiology*; D000249:Adenosine Monophosphate; D000818:Animals; D001773:Blood Cells / Q000166:cytology*; D001854:Bone Marrow Cells; D002455:Cell Division / Q000187:drug effects / Q000502:physiology* / Q000528:radiation effects; D004176:Dipyridamole; D005720:Gamma Rays; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D013154:Spleen / Q000166:cytology
D000249:Adenosine Monophosphate; D004176:Dipyridamole; D000241:Adenosine