title: Therapeutic alternatives for the hirsute woman.
abstract: A retrospective analysis of 21 hirsute women seen at a gynaecological endocrine clinic revealed a high incidence of infertility, menstrual irregularities and abnormal androgen profile. Polycystic ovarian syndrome (PCOS) was the underlying abnormality in the majority of cases. Cyproterone acetate (CPA) with ethinyl oestradiol in a reverse sequential regime was more effective and better tolerated but much more expensive than the combination of spironolactone and the oral contraceptive pill (OCP).
authors.affiliation: Mount Hope Women's Hospital, Trinidad.
authors.forename: B
authors.initials: B
authors.lastname: Bassaw
authors.forename: R
authors.initials: R
authors.lastname: Maharaj
authors.forename: A
authors.initials: A
authors.lastname: Ali
authors.forename: S
authors.initials: S
authors.lastname: Roopnarinesingh
mesh_terms: D000293:Adolescent; D000328:Adult; D000726:Androgen Antagonists / Q000627:therapeutic use*; D003534:Cyproterone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D017373:Cyproterone Acetate; D004359:Drug Therapy, Combination; D004997:Ethinyl Estradiol / Q000627:therapeutic use*; D005260:Female; D006628:Hirsutism / Q000188:drug therapy* / Q000191:economics; D006801:Humans; D012189:Retrospective Studies; D013148:Spironolactone / Q000627:therapeutic use*; D014300:Trinidad and Tobago
chemical_list: D000726:Androgen Antagonists; D013148:Spironolactone; D004997:Ethinyl Estradiol; D017373:Cyproterone Acetate; D003534:Cyproterone