title: Neonatal hypertension. Incidence and risk factors.
abstract: To determine the incidence and risk factors for neonatal hypertension we studied the entire population of 3179 infants admitted to our neonatal intensive care unit over a 6-year period. We report a 0.81% (26/3179) incidence of hypertension in this population. In 13 patients (50%) the hypertension was renal in origin. In four patients (15.4%), the etiology of hypertension could not be determined. Significant risk factors for neonatal hypertension included: bronchopulmonary dysplasia (5.9% in affected infants v 0.5% in unaffected infants, P less than .001); patent ductus arteriosus (3.07% in affected v 0.5% in unaffected infants, P less than .001); intraventricular hemorrhage (2.89% in affected infants v 0.56% in unaffected infants, P less than .001); and umbilical arterial catheterization (8.8% v 0.2% in infants with and without catheterization, respectively, P less than .001).
authors.affiliation: Department of Pediatrics, Loyola University of Chicago, Maywood, Illinois.
authors.forename: H P
authors.initials: HP
authors.lastname: Singh
authors.forename: R M
authors.initials: RM
authors.lastname: Hurley
authors.forename: T F
authors.initials: TF
authors.lastname: Myers
mesh_terms: D001997:Bronchopulmonary Dysplasia / Q000150:complications; D002404:Catheterization; D004374:Ductus Arteriosus, Patent / Q000150:complications; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000453:epidemiology* / Q000209:etiology; D015994:Incidence; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D008297:Male; D012083:Renin / Q000097:blood; D012307:Risk Factors; D014469:Umbilical Arteries
chemical_list: D012083:Renin