Antiplaque efficacy of a prebrushing rinse.
One-hundred forty-nine (149) healthy adult subjects completed a single-use, supervised trial, and 143 subjects completed a 6-week trial to determine the effect of rinsing with Plax prebrushing mouthrinse on supragingival plaque reduction. During the single-use trial, plaque was scored both initially and after subjects rinsed with Plax or a negative control rinse and then brushed with a dentifrice. Following a dental prophylaxis subjects then began a "home-use" phase of rinsing prior to normal brushing, twice daily for 6 weeks, at which time plaque was rescored. In the single-use trial, Plax and control rinses produced 21% and 22% reductions in plaque scores respectively. In the 6-week trial, Plax and control rinses produced 10% and 11% reductions in plaque scores respectively. In all cases, Plax was no more effective than the control rinse in enhancing the plaque-removal effectiveness of toothbrushing.
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D000293:Adolescent; D000328:Adult; D001565:Benzoates / Q000627:therapeutic use*; D003773:Dental Plaque / Q000517:prevention & control*; D003774:Dental Plaque Index; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009067:Mouthwashes / Q000627:therapeutic use*; D012967:Sodium Dodecyl Sulfate / Q000627:therapeutic use*; D014099:Toothbrushing
D001565:Benzoates; D009067:Mouthwashes; C070868:Plax; D012967:Sodium Dodecyl Sulfate