title: Analysis of cerebrospinal fluid from field cases of some common ovine neurological diseases.
abstract: Analysis of cerebrospinal fluid (CSF) samples from normal sheep and from cases of some common neurological diseases revealed a significant increase (P less than 0.05) in the group mean CSF protein concentration for meningitis, listeriosis and spinal abscess but not for scrapie, spinal injury, ovine pregnancy toxaemia or polioencephalomalacia. The CSF white blood cell count (WBC) was significantly increased (P less than 0.05) in the meningitis group and in those cases of listeriosis which failed to respond to antibiotic therapy. All cases of bacterial infection of the central nervous system (CNS) could be identified by the combined interpretation of the protein concentration and the differential WBC count. It is concluded that CSF analysis is useful clinically in differentiating traumatic from infective spinal lesions and toxic or metabolic lesions from bacterial meningitis in sheep.
authors.affiliation: Department of Veterinary Clinical Studies, Royal (Dick) School of Veterinary Studies, Roslin, Midlothian.
authors.forename: P R
authors.initials: PR
authors.lastname: Scott
mesh_terms: D000818:Animals; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis; D007958:Leukocyte Count / Q000662:veterinary; D009422:Nervous System Diseases / Q000134:cerebrospinal fluid / Q000662:veterinary*; D012756:Sheep; D012757:Sheep Diseases / Q000134:cerebrospinal fluid*; D013046:Specific Gravity; D013129:Spinal Puncture / Q000662:veterinary
chemical_list: D002556:Cerebrospinal Fluid Proteins