Periconceptional supplementation with folic acid. Does it prevent neural tube defects?
There has been considerable controversy in recent years concerning the benefit of periconceptional vitamin supplementation in the prevention of neural tube defects. Recent reports of a successful randomized clinical trial have prompted official recommendations for folic acid supplementation in women with a history of an affected pregnancy. Periconceptional supplementation of low-risk women remains controversial.
Murphy
P A
PA
Columbia University School of Nursing, New York, NY 10032.
D005069:Evaluation Studies as Topic; D005492:Folic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D009436:Neural Tube Defects / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D016742:Preconception Care / Q000592:standards*; D011295:Prenatal Care / Q000592:standards*
D005492:Folic Acid