Synthesis of some carbamates of myo-inositol.
The syntheses are described of the 1-O-carbamoyl (11), 1-O-carbamoyl-2-O-stearoyl (10), 1-O-(acetylcarbamoyl)-2-O-stearoyl (12), 1-O-(heptylcarbamoyl) (13), 2-O-(heptylcarbamoyl) (14) 1,2-di-O-(heptylcarbamoyl) (15), and 1-O-(octadecylcarbamoyl) (16) derivatives of myo-inositol. None of these compounds had significant activity against phospholipase C.
Brufani
M
M
Dipartimento di Scienze Biochimiche A. Rossi Fanelli, Università La Sapienza, Roma, Italy.
Cesta
M C
MC
Donnarumma
L
L
Filocamo
L
L
Gostoli
G
G
Lappa
S
S
Ferrari
E
E
Pagella
P G
PG
D002219:Carbamates / Q000138:chemical synthesis* / Q000494:pharmacology; D007294:Inositol / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000494:pharmacology; D015394:Molecular Structure; D010738:Type C Phospholipases / Q000037:antagonists & inhibitors
D002219:Carbamates; D007294:Inositol; D010738:Type C Phospholipases