[The prevention of postoperative deep venous thrombosis with heparan sulfate per os. A controlled clinical study vs. heparin calcium].
The paper reports the results of a randomised study carried out on a pool of 100 patients undergoing surgery in order to assess the efficacy and tolerability of orally administered heparan sulfate versus heparin calcium in the prevention of postoperative deep-vein thrombosis. Despite the limits of oral administration, heparan sulfate is indicated in the pharmacological prevention of postoperative deep-vein thrombosis.
Seccia
M
M
Cattedra di Chirurgia d'Urgenza, Università degli Studi di Pisa.
Bellomini
M G
MG
Goletti
O
O
Tortora
A
A
Buccianti
P
P
Chiarugi
M
M
Bertolucci
A
A
Martino
M C
MC
Macaluso
C
C
Cavina
E
E
D000284:Administration, Oral; D004361:Drug Tolerance; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006493:Heparin / Q000008:administration & dosage*; D006497:Heparan Sulfate / Q000008:administration & dosage*; D006801:Humans; D011183:Postoperative Complications / Q000517:prevention & control*; D013514:Surgical Procedures, Operative / Q000009:adverse effects; D013924:Thrombophlebitis / Q000517:prevention & control*
D005343:Fibrinolytic Agents; D006493:Heparin; D006497:Heparan Sulfate; C006871:calcium heparin
Prevenzione della trombosi venosa profonda postoperatoria con eparansolfato per os. Studio clinico controllato vs eparina calcica.