title: Lung function in silicosis.
abstract: In order to assess the effect of silicosis on lung function, 61 gold miners with radiological silicosis were compared with 61 controls. Each pair was matched for age, dust exposure, and smoking habits. A full range of lung function tests was performed, and with two exceptions the results showed no significant differences between the two groups. The exceptions are the slope of the alveolar plateau (phase 3) and the closing volume, for which the silicotic cases had significantly higher values. The reason for the higher readings in the silicotic patients remains unexplained.
authors.affiliation: Epidemiology Research Unit, Medical Bureau for Occupational Diseases, Johannesburg, South Africa.
authors.forename: F J
authors.initials: FJ
authors.lastname: Wiles
authors.forename: E
authors.initials: E
authors.lastname: Baskind
authors.forename: P A
authors.initials: PA
authors.lastname: Hessel
authors.forename: B
authors.initials: B
authors.lastname: Bezuidenhout
authors.forename: E
authors.initials: E
authors.lastname: Hnizdo
mesh_terms: D001784:Blood Gas Analysis; D006801:Humans; D008168:Lung / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D012129:Respiratory Function Tests; D012829:Silicosis / Q000503:physiopathology*; D014797:Vital Capacity