title: Stereotaxic needle localization and biopsy of occult breast lesions: first year's experience.
abstract: During a 12-month period 115 patients with abnormal mammograms had stereotaxic needle localization and biopsy of nonpalpable breast lesions. The procedure was performed on a Fischer Mammotest II machine (Fischer Imaging; Denver, CO) and the biopsies were taken with a #18 gauge Bard biopsy needle using a Bard biopty gun (distributed by Bard Urological; Covington, GA; manufactured by Radiplast; Uppsala, Sweden). Mammographic lesions were suspicious matrix densities (85), clustered microcalcifications (22), or a combination of both (8). The pathologist recommended open biopsy in 16 per cent (18/115) of the patients. Pathology on the 18 open biopsies revealed that 11 (9 matrix densities and 2 calcifications) were carcinomas and true positives, whereas the other 7 (all matrix densities) were benign mastopathies and false positives. Further analysis of the pathologic data showed that there were three possible diagnoses from the needle biopsies on the patients that later went to open biopsy: cancer (6), very suspicious lesion (9), and slightly suspicious lesion without atypical hyperplasia (3). All 6 cancers were confirmed by open biopsy; about half (5/9) of the very suspicious lesions were cancer and none (0/3) of the slightly suspicious lesions were cancer. More cases, followed by open biopsy, are needed to refine the selection procedure for open biopsy and careful follow-up of the patients who did not have open biopsy will also be needed to determine the false negative rate. Excellent patient acceptance was found and the test was easy to perform in the office without serious complications. Furthermore, the test was cost effective because it avoided open biopsy in 97 patients.
authors.affiliation: Breast Clinic, Mastology Center, Baton Rouge, LA 70816.
authors.forename: R L
authors.initials: RL
authors.lastname: Elliott
authors.forename: A E
authors.initials: AE
authors.lastname: Haynes
authors.forename: J A
authors.initials: JA
authors.lastname: Bolin
authors.forename: E M
authors.initials: EM
authors.lastname: Boagni
authors.forename: J F
authors.initials: JF
authors.lastname: Head
mesh_terms: D001707:Biopsy, Needle / Q000295:instrumentation / Q000379:methods; D001940:Breast / Q000473:pathology; D001941:Breast Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology; D002114:Calcinosis / Q000473:pathology; D002277:Carcinoma / Q000473:pathology; D005260:Female; D005348:Fibrocystic Breast Disease / Q000473:pathology; D005355:Fibrosis; D006801:Humans; D008327:Mammography / Q000295:instrumentation; D013238:Stereotaxic Techniques / Q000295:instrumentation