Urolithiasis in childhood: metabolic evaluation.
In order to determine metabolic disorders in children with urolithiasis, 50 patients with urinary calculi were studied. Abdominal pain and/or haematuria were the most predominant symptoms. Surgical procedures were required in 22% of these children and urinary tract infection was observed in 34% of this group. Only 2 children had anatomical malformations of the urinary tract. Absorptive hypercalciuria (32%), renal hypercalciuria (34%) and uric acid hyperexcretion (24%) were the most common metabolic abnormalities in these children. We were unable to find an underlying metabolic abnormality in only 14% of the patients. These data suggest that appropriate metabolic study will allow rational management of children with urinary stones.
Perrone
H C
HC
Department of Medicine, Escola Paulista of Medicina, São Paulo, Brazil.
dos Santos
D R
DR
Santos
M V
MV
Pinheiro
M E
ME
Toporovski
J
J
Ramos
O L
OL
Schor
N
N
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003404:Creatinine / Q000378:metabolism; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000378:metabolism; D007223:Infant; D008297:Male; D014527:Uric Acid / Q000378:metabolism; D014545:Urinary Calculi / Q000209:etiology / Q000378:metabolism*; D014552:Urinary Tract Infections / Q000378:metabolism
D014527:Uric Acid; D003404:Creatinine