title: Evaluation of sperm morphology using Kruger's strict criteria.
abstract: Prospective and retrospective studies were conducted to evaluate sperm morphology using strict criteria for predicting fertilization capacity in males. Severely impaired male fertility potential was measured by a result of less than or equal to 4% (denotes percentage sperm having normal morphology) and scores of greater than 14% indicated normal fertilization potential. There were no statistically significant differences found in pregnancy rates in partners of men with normal morphology of less than or equal to 4% vs. those with 14% or greater (chi 2 analysis): the prospective study showed a 41% pregnancy rate in less than or equal to 4% group vs. 29% rate in greater than 14% group (p = 0.44 NS); the retrospective analysis showed a 50% pregnancy rate in the group with less than or equal to 4% morphology scores vs. 67% in greater than 14% group (p = 0.45 NS). When only the men with normal motile density (greater than 10 x 10(6)/ml) were evaluated, a statistical difference was found in the retrospective study between the group with morphology results greater than 14% (93%) vs. the group less than or equal to 4% (40%). However, the 56% success rate in the men with less than 10 x 10(6)/ml sperm and normal morphology less than or equal to 4% reduces the significance of the diagnosis of sperm morphology using the new strict criteria.
authors.affiliation: Department of Obstetrics and Gynecology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School of Camden, Cooper Hospital/University Medical Center.
authors.forename: J H
authors.initials: JH
authors.lastname: Check
authors.forename: H G
authors.initials: HG
authors.lastname: Adelson
authors.forename: B R
authors.initials: BR
authors.lastname: Schubert
authors.forename: A
authors.initials: A
authors.lastname: Bollendorf
mesh_terms: D005069:Evaluation Studies as Topic; D006801:Humans; D007248:Infertility, Male / Q000453:epidemiology; D008297:Male; D011446:Prospective Studies; D012189:Retrospective Studies; D013081:Sperm Motility / Q000502:physiology; D013094:Spermatozoa / Q000166:cytology* / Q000502:physiology; D013223:Statistics as Topic