title: Left ventricular function is not impaired in weight-lifters who use anabolic steroids.
abstract: Recent reports suggest that anabolic steroid use might deleteriously affect left ventricular function. To examine this possibility, the present study measured left ventricular size and function with use of Doppler echocardiographic techniques in 23 weight lifters: 12 who were currently using anabolic steroids and 11 who reported that they had never used these drugs. Drug users had administered anabolic steroids to themselves for at least three cycles over the past year. All studies were interpreted by blind review and group assignment was confirmed by urine testing. Average age, years of exercise training and body weight, as well as heart rate and blood pressure at rest were similar in both groups. Cardiac dimensions (mean +/- SD) including left ventricular diastolic cavity diameter (57 +/- 3 vs. 56 +/- 5 mm), septal thickness (10 +/- 2 vs. 9 +/- 1 mm), posterior wall thickness (8 +/- 1 vs. 8 +/- 1 mm) and myocardial mass (149 +/- 27 vs. 135 +/- 21 g) did not differ between the anabolic steroid users and nonusers, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Miriam Hospital, Providence, Rhode Island 02906.
authors.forename: P D
authors.initials: PD
authors.lastname: Thompson
authors.forename: A
authors.initials: A
authors.lastname: Sadaniantz
authors.forename: E M
authors.initials: EM
authors.lastname: Cullinane
authors.forename: K S
authors.initials: KS
authors.lastname: Bodziony
authors.forename: D H
authors.initials: DH
authors.lastname: Catlin
authors.forename: G
authors.initials: G
authors.lastname: Torek-Both
authors.forename: P S
authors.initials: PS
authors.lastname: Douglas
mesh_terms: D000328:Adult; D045930:Anabolic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001827:Body Height; D001835:Body Weight; D006332:Cardiomegaly / Q000139:chemically induced* / Q000000981:diagnostic imaging; D004300:Doping in Sports; D004452:Echocardiography; D015150:Echocardiography, Doppler; D006801:Humans; D008297:Male; D013997:Time Factors; D016277:Ventricular Function, Left / Q000187:drug effects*; D014891:Weight Lifting
chemical_list: D045930:Anabolic Agents