[Effect of Ginkgo-biloba extract on mental performance. Double-blind study using computerized measurement conditions in patients with cerebral insufficiency].
OBJECTIVE
The effect of ginkgo biloba extract EGb 761 on basic parameters of mental performance.


METHODS
Seventy-two outpatients with cerebral insufficiency at three test centers.


METHODS
Double-blind, randomized placebo-controlled study of 24 weeks duration. Test parameters: Psychometric computer-aided examination of the short-term memory and basic learning rate.


RESULTS
Statistically significant improvement in the shortterm memory after 6 weeks and of the learning rate after 24 weeks in the test substance group, but not in the placebo group (longitudinal analysis). The difference between the test substance and placebo groups (horizontal analysis) reached statistical significance in the 24th week.


CONCLUSIONS
Treatment with ginkgo biloba extract EGb 761 improves mental/mnestic performance.
Grässel
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Abteilung für Medizinische Psychologie und Psychopathometrie, Universität Erlangen-Nürnberg.
D000368:Aged; D002561:Cerebrovascular Disorders / Q000523:psychology / Q000628:therapy*; D003627:Data Interpretation, Statistical; D004311:Double-Blind Method; D005260:Female; D020441:Ginkgo biloba; D006801:Humans; D008297:Male; D008606:Mental Processes / Q000187:drug effects*; D008875:Middle Aged; D010936:Plant Extracts / Q000627:therapeutic use*; D015203:Reproducibility of Results; D000096983:Ginkgo Extract
D010936:Plant Extracts; C063170:Ginkgo biloba extract; D000096983:Ginkgo Extract
Einfluss von Ginkgo-biloba-Extrakt auf die geistige Leistungsfähigkeit. Doppelblindstudie unter computerisierten Messbedingungen bei Patienten mit Zerebralinsuffizienz.