title: Epithelioid sarcoma. Flow cytometric study of DNA content and regional DNA heterogeneity.
abstract: The DNA content and regional DNA heterogeneity in correlation with clinicopathologic parameters and patient survival were investigated in epithelioid sarcoma. Such neoplasms preponderantly manifest diploid DNA content and a remarkably stable intratumoral and intertumoral DNA content. Small tumor size (less than 5.0 cm) and low S-phase fraction (less than 5%) were significant prognostic factors in this study. Ploidy status, mitotic rate, age, and postsurgical treatment were not significantly correlated with survival.
authors.affiliation: Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
authors.forename: A K
authors.initials: AK
authors.lastname: el-Naggar
authors.forename: G M
authors.initials: GM
authors.lastname: Garcia
mesh_terms: D000293:Adolescent; D000328:Adult; D004273:DNA, Neoplasm / Q000032:analysis* / Q000235:genetics; D005260:Female; D005434:Flow Cytometry; D005500:Follow-Up Studies; D014644:Genetic Variation / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011003:Ploidies; D012509:Sarcoma / Q000737:chemistry* / Q000235:genetics / Q000401:mortality; D012983:Soft Tissue Neoplasms / Q000737:chemistry* / Q000235:genetics / Q000401:mortality
chemical_list: D004273:DNA, Neoplasm