title: Diminished nocturnal penile tumescence in depression: a replication study.
abstract: A descriptive study was conducted in a new sample of 51 men with DSM-III-R research diagnostic criteria (RDC) major depression in order to replicate earlier observations that measures of nocturnal penile tumescence (NPT) and penile rigidity are disturbed in depressive states. When compared to both the age-equated patient (n = 34) and normal control (n = 28) groups reported in our 1988 study, the new sample manifested significant abnormalities of NPT and diminished penile rigidity. Such disturbances were not, however, significantly correlated with psychobiological indicators of severe or endogenous depression.
authors.affiliation: Department of Psychiatry, University of Pittsburgh School of Medicine, Pennsylvania 15213.
authors.forename: M E
authors.initials: ME
authors.lastname: Thase
authors.forename: C F
authors.initials: CF
authors.lastname: Reynolds
authors.forename: J R
authors.initials: JR
authors.lastname: Jennings
authors.forename: E
authors.initials: E
authors.lastname: Frank
authors.forename: G L
authors.initials: GL
authors.lastname: Garamoni
authors.forename: E A
authors.initials: EA
authors.lastname: Nofzinger
authors.forename: A L
authors.initials: AL
authors.lastname: Fascizka
authors.forename: D J
authors.initials: DJ
authors.lastname: Kupfer
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D003866:Depressive Disorder / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010410:Penile Erection / Q000502:physiology*; D012890:Sleep / Q000502:physiology