Pseudoautosomal repeat displays higher variability in blacks than in Caucasians.
DNA patterns from a pseudoautosomal variable number tandem repeat-like minisatellite (locus DXYS20) were compared in two samples: a Caucasian and a Black sample. We defined 3 types of DNA patterns named A, B and C, and found that these patterns have different frequencies in the Caucasian and Black groups. A set of alleles (the C group) in 48% of the Black sample is not found in the Caucasian sample. We also found a greater degree of fragment-size variability among Black individuals than among those of Caucasian origin. The large degree of ethnic variation indicates that this locus will be useful in population genetic studies.
Rappold
G A
GA
Institut für Humangenetik Universität, Heidelberg, Federal Republic of Germany.
Henke
A
A
Pohlschmid
M
M
Huisman
T H
TH
D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D044383:Black People / Q000235:genetics*; D015139:Blotting, Southern; D003001:Cloning, Molecular; D003360:Cosmids; D004247:DNA / Q000235:genetics*; D015342:DNA Probes; D014644:Genetic Variation; D006239:Haplotypes; D006801:Humans; D008969:Molecular Sequence Data; D012091:Repetitive Sequences, Nucleic Acid; D015183:Restriction Mapping; D044465:White People / Q000235:genetics*
D015342:DNA Probes; D004247:DNA