[Total synthesis and properties of prostaglandins. XXXI. Synthesis of pyranylated and glycosidated omega-hydroxyalkyl ethers of 11- deoxyprostaglandin E1].
Four methods of the synthesis of model glycosides with 11-deoxyprostaglandin E1 and a connecting polymethylene chain as the aglycone are compared. Interaction of potassium salt of prostaglandin PG with omega-iodoalkylglycosides is the most promising approach.
Sokolov
G P
GP
Kaula
I Ia
IIa
Freĭmanis
Ia F
IaF
Turovskiĭ
I V
IV
Gavars
M P
MP
D000527:Alprostadil / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D004952:Esters / Q000138:chemical synthesis; D006027:Glycosides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D011458:Prostaglandins E / Q000138:chemical synthesis*
D004952:Esters; D006027:Glycosides; D011458:Prostaglandins E; D000527:Alprostadil; C034008:11-deoxyprostaglandin E1
Total'nyĭ sintez i svoĭstva prostaglandinov. XXXI. Sintez piranilirvannykh i glikozidirovannykh omega-gidroksialkilovykh éfirov 11-dezoksiprostaglandina E1.