Lymphocyte count as a prognostic factor in childhood cancer.
To evaluate the significance of the peripheral lymphocyte count in the prognostication of childhood cancer, 173 children with cancer (neuroblastoma, non-Hodgkin's lymphoma, malignant lymphogranuloma, nephroblastoma, Ewing's sarcoma, and rhabdomyosarcoma) were studied. All patients with the above-mentioned diagnoses admitted for the first time between 1985 and 1987 without prior treatment and acute infection were eligible for the study. Elevated peripheral lymphocyte count seems to be an independent indicator of survival from neuroblastoma but not from other tumors.
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Department of Paediatric Oncology, Teaching Hospital Motol, Prague, Czechoslovakia.
D000293:Adolescent; D000367:Age Factors; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007958:Leukocyte Count; D008214:Lymphocytes; D009369:Neoplasms / Q000097:blood / Q000401:mortality* / Q000628:therapy; D009447:Neuroblastoma / Q000097:blood / Q000401:mortality / Q000628:therapy; D011379:Prognosis; D011446:Prospective Studies; D011878:Radiotherapy; D016019:Survival Analysis; D015996:Survival Rate