title: Double-blind randomized trial of nicotinamide on early-onset diabetes.
abstract: OBJECTIVE
  To determine the efficacy of nicotinamide in inducing remission in early-onset insulin-dependent diabetes mellitus.
  
  
  METHODS
  This study was a double-blind, randomized clinical trial.
  
  
  CONCLUSIONS
  Nicotinamide failed to induce remission or differences on beta-cell secretion between the two groups.
authors.affiliation: Department of Medicine, School of Medicine, College of Pharmacy, University of Minnesota, Minneapolis 55455.
authors.forename: C M
authors.initials: CM
authors.lastname: Lewis
authors.forename: D M
authors.initials: DM
authors.lastname: Canafax
authors.forename: J M
authors.initials: JM
authors.lastname: Sprafka
authors.forename: J J
authors.initials: JJ
authors.lastname: Barbosa
mesh_terms: D015190:Blood Glucose Self-Monitoring; D002096:C-Peptide / Q000097:blood; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000188:drug therapy*; D004311:Double-Blind Method; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D009536:Niacinamide / Q000627:therapeutic use*; D012074:Remission Induction
chemical_list: D002096:C-Peptide; D006442:Glycated Hemoglobin; D009536:Niacinamide