Atypical cytologic features of medullary carcinoma of the thyroid. A review of 12 cases.
A total of 12 cases of medullary carcinoma of the thyroid were reviewed with regard to atypical cytologic features. They included clusters of cells with a follicular arrangement, papillary fronds, spindle-shaped cells, pleomorphic nuclei, nucleoli and intranuclear inclusions. Congo red staining on selected destained smears was positive for amyloid in three cases. Histology was also available in 12 cases. Two cases were incorrectly diagnosed as papillary carcinoma and one as follicular carcinoma on cytology. There were no false-positive diagnoses.
Das
A
A
Department of Cytology, Post-graduate Institute of Medical Education and Research, Chandigarh, India.
Gupta
S K
SK
Banerjee
A K
AK
Srinivasan
R
R
Radotra
B D
BD
Nijhawan
R
R
Dey
P
P
Rajwanshi
A
A
D000230:Adenocarcinoma / Q000473:pathology* / Q000648:ultrastructure; D002277:Carcinoma / Q000473:pathology* / Q000648:ultrastructure; D002291:Carcinoma, Papillary / Q000473:pathology* / Q000648:ultrastructure; D003937:Diagnosis, Differential; D006801:Humans; D012189:Retrospective Studies; D013964:Thyroid Neoplasms / Q000473:pathology* / Q000648:ultrastructure