title: [Hepatitis-B vaccination: unresolved questions].
abstract: There is no doubt about the efficacy and safety of hepatitis B vaccines; however, problems regarding the duration of protection, the nonresponders or the optimum vaccination strategies are not yet completely solved. It has been shown recently that the duration of protection is longer than initially assumed; a revaccination after 5 years seems to be sufficient for all who responded well to the vaccination initially. There is no other measure available to treat nonresponders than by further vaccinations, which, however, is successful in more than half of these individuals. The present strategy in industrialized countries to vaccinate only risk groups has influenced the hepatitis B incidence in these countries only marginally; only the vaccination of all children will reduce the burden of hepatitis B significantly.
authors.affiliation: Max-von-Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Universität München.
authors.forename: W
authors.initials: W
authors.lastname: Jilg
mesh_terms: D006509:Hepatitis B / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission; D017325:Hepatitis B Vaccines; D006801:Humans; D007115:Immunization Schedule; D007223:Infant; D013997:Time Factors; D014614:Vaccines, Synthetic; D014761:Viral Hepatitis Vaccines
chemical_list: D017325:Hepatitis B Vaccines; D014614:Vaccines, Synthetic; D014761:Viral Hepatitis Vaccines
vernacular_title: Hepatitis-B-Impfung: ungelöste Probleme.