[Cardiocirculatory arrest after administration of combined mifepristone (Mifegyne) and sulprostone (Nalador) for induced abortion. Possible role of coronary vasospasm].
Reversible ventricular fibrillation occurred in a 35 year old multiparous woman after the administration of the association mifepristone (Mifegyne) and sulprostone (Nalador) for therapeutic abortion. A coronary spasm induced by the analogue of the prostaglandin PGE 2x was though to be the causative mechanism and was reproduced by the Ergonovine test. The evolution of the ECG and myocardial scintigraphy suggested a slowly regressive stunned myocardium.
Delay
M
M
Service de cardiologie, hôpital Purpan, Toulouse.
Genestal
M
M
Carrie
D
D
Livarek
B
B
Boudjemaa
B
B
Bernadet
P
P
D000020:Abortifacient Agents, Nonsteroidal / Q000009:adverse effects*; D000032:Abortion, Therapeutic / Q000379:methods*; D003329:Coronary Vasospasm / Q000139:chemically induced* / Q000503:physiopathology; D015232:Dinoprostone / Q000009:adverse effects / Q000031:analogs & derivatives*; D004338:Drug Combinations; D004554:Electric Countershock; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging; D006323:Heart Arrest / Q000139:chemically induced* / Q000503:physiopathology; D006801:Humans; D015735:Mifepristone / Q000009:adverse effects*; D011247:Pregnancy; D011877:Radionuclide Imaging; D012307:Risk Factors; D013794:Thallium Radioisotopes; D014693:Ventricular Fibrillation / Q000139:chemically induced* / Q000628:therapy
D000020:Abortifacient Agents, Nonsteroidal; D004338:Drug Combinations; D013794:Thallium Radioisotopes; D015735:Mifepristone; C016767:sulprostone; D015232:Dinoprostone
Arrêt cardiocirculatoire après administration de l'association mifépristone (Mifégyne) sulprostone (Nalador) pour interruption de grossesse. Rôle évoqué du spasme coronaire.