title: Non-Hodgkin lymphoma in the porta hepatis after orthotopic liver transplantation: sonographic findings.
abstract: The sonographic appearances of primary non-Hodgkin lymphoma developing in the porta hepatis in three patients soon after hepatic transplantation were reviewed. The lymphomas appeared as large hypoechoic masses encasing vital portal structures--the hepatic artery and the common bile duct--in all three cases and displacing the portal vein in two. The liver was only locally involved. All patients presented with jaundice soon after transplantation (average interval, 6.3 months). Rapid tumor progression caused hepatic infarction, necessitating retransplantation in two patients. The third patient died shortly after diagnosis. The authors believe this complication will be seen increasingly as liver transplantation becomes more common. Non-Hodgkin lymphoma should be considered when an obstructing mass is found in the porta hepatis, even when the time interval since transplantation is short.
authors.affiliation: Department of Diagnostic Imaging, Toronto General Division, Toronto Hospital, Ont, Canada.
authors.forename: A R
authors.initials: AR
authors.lastname: Moody
authors.forename: S R
authors.initials: SR
authors.lastname: Wilson
authors.forename: P D
authors.initials: PD
authors.lastname: Greig
mesh_terms: D003135:Common Bile Duct / Q000000981:diagnostic imaging; D016572:Cyclosporine / Q000009:adverse effects; D006499:Hepatic Artery / Q000000981:diagnostic imaging; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D008099:Liver / Q000000981:diagnostic imaging*; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000209:etiology; D016031:Liver Transplantation / Q000000981:diagnostic imaging*; D016393:Lymphoma, B-Cell / Q000000981:diagnostic imaging* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D014463:Ultrasonography
chemical_list: D016572:Cyclosporine