[The clinical picture and outcome of acute delta infection].
A total of 60 patients were observed with acute hepatitis delta defined at examination of 200 adult subjects with acute HBsAg-positive hepatitis. Moderate and severe forms of the disease occurred more frequently, lethality reached 13.3%. An unfavorable prognosis was related to a short-term prejaundice period with intoxication (high body temperature, head ache, vertigo, recurrent vomiting, IgM antibodies presence in the serum at the height of the disease). No patients achieved cure within 9 months following the discharge from hospital. The process acquired the form of long-term convalescence with transformation into chronic hepatitis delta.
Negresku
G V
GV
Iashina
T L
TL
Burkov
A N
AN
Favorov
M O
MO
D000208:Acute Disease; D000328:Adult; D015415:Biomarkers / Q000097:blood; D003289:Convalescence; D005260:Female; D006508:Hepatitis Antibodies / Q000097:blood; D006509:Hepatitis B / Q000453:epidemiology; D006514:Hepatitis B Surface Antigens / Q000097:blood; D003699:Hepatitis D / Q000175:diagnosis* / Q000453:epidemiology / Q000401:mortality; D003698:Hepatitis Delta Virus / Q000276:immunology; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008966:Moldova / Q000453:epidemiology; D011379:Prognosis; D013997:Time Factors
D015415:Biomarkers; D006508:Hepatitis Antibodies; D006514:Hepatitis B Surface Antigens; D007075:Immunoglobulin M
Klinika i iskhody ostrogo del'ta-gepatita.