title: [Pericardial manifestations of toxoplasmosis].
abstract: A case of pericarditis due to toxoplasmosis in a 20 year old non-immune depressed man with a favourable outcome with specific antiparasitic treatment is reported. Pericarditis is rare in toxoplasmosis and does not require an associated immune deficiency. The clinical presentation is that of acute benign pericarditis, the diagnosis depending on positive toxoplasmosis serology (positive IgM or increasing IgG antibody titres) and the absence of another obvious cause. Isolation of the parasite by direct examination or animal inoculation is very rare. The spontaneous evolution is to pericardial constriction whilst specific antibiotic therapy (sulfadiazine-pyrimethamine) leads to a rapid cure in most cases. This underlines the necessity of searching for toxoplasmosis in patients with unexplained pericarditis.
authors.affiliation: Service de cardiologie, hôpital Beaujon, Clichy.
authors.forename: E
authors.initials: E
authors.lastname: Guérot
authors.forename: P
authors.initials: P
authors.lastname: Assayag
authors.forename: C
authors.initials: C
authors.lastname: Morgant
authors.forename: M
authors.initials: M
authors.lastname: Hess
authors.forename: P E
authors.initials: PE
authors.lastname: Valère
mesh_terms: D000328:Adult; D004359:Drug Therapy, Combination; D004452:Echocardiography; D004562:Electrocardiography; D006801:Humans; D008297:Male; D010490:Pericardial Effusion / Q000000981:diagnostic imaging / Q000209:etiology*; D010493:Pericarditis / Q000000981:diagnostic imaging / Q000209:etiology*; D011739:Pyrimethamine / Q000627:therapeutic use; D013411:Sulfadiazine / Q000627:therapeutic use; D014123:Toxoplasmosis / Q000150:complications* / Q000188:drug therapy
chemical_list: D013411:Sulfadiazine; D011739:Pyrimethamine
vernacular_title: Manifestations péricardiques de la toxoplasmose.