title: Experimental study of high-frequency two-way jet ventilation.
abstract: METHODS
  A new mode of jet ventilation, high-frequency two-way jet ventilation, was devised and introduced to increase CO2 elimination. High-frequency two-way jet ventilation was achieved by adding reverse jet pulses inside the trachea through an intratracheal reverse jet system to the expiratory phase of common high-frequency jet ventilation. The ventilatory efficiency and features of high-frequency two-way jet ventilation were investigated and compared with those features of high-frequency jet ventilation in ten dogs in the same experimental condition. Random sample selection and randomized crossover trial were used for comparison between high-frequency two-way jet ventilation and high-frequency jet ventilation. Peak inspiratory pressure, end-expiratory pressure, and the arterial blood gas variables (PaO2, PaCO2, and pH) were measured during the study.
  
  
  RESULTS
  PaCO2 with high-frequency two-way jet ventilation was about 35% lower than that with high-frequency jet ventilation (from 45 to 29 torr [6.0 to 3.9 kPa], p less than .01). Simultaneously, peak inspiratory pressure and end-expiratory pressure during high-frequency two-way jet ventilation were significantly lower than those same variables measured during high-frequency jet ventilation. End-expiratory pressure of high-frequency two-way jet ventilation was a negative pressure (-2.45 +/- 0.45 cm H2O). The pH of high-frequency two-way jet ventilation was significantly higher than that of high-frequency jet ventilation.
  
  
  CONCLUSIONS
  Compared with high-frequency jet ventilation, high-frequency two-way jet ventilation demonstrated a ventilatory feature of increasing CO2 elimination and simultaneously decreasing airway pressure.
authors.affiliation: Department of Anesthesiology, Tongji Hospital, Tongji Medical University, Wuhan, Hubei, China.
authors.forename: H
authors.initials: H
authors.lastname: Wei
authors.forename: S A
authors.initials: SA
authors.lastname: Jin
authors.forename: Z
authors.initials: Z
authors.lastname: Ma
authors.forename: H
authors.initials: H
authors.lastname: Bi
authors.forename: X
authors.initials: X
authors.lastname: Ba
mesh_terms: D000818:Animals; D002245:Carbon Dioxide / Q000097:blood / Q000378:metabolism*; D004285:Dogs; D005260:Female; D006611:High-Frequency Jet Ventilation / Q000295:instrumentation*; D008168:Lung / Q000378:metabolism*; D008297:Male; D010100:Oxygen / Q000097:blood
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen