title: POEMS syndrome presenting with cardiomegaly and cardiomyopathy.
abstract: A rare association of multisystemic manifestations with plasma cell dyscrasia has been termed POEMS syndrome, which includes polyneuropathy, organomegaly, endocrinopathy. M-protein, and skin changes. From literature reports, organomegaly consists of hepatosplenomegaly and/or lymphadenopathy. We here present a case of POEMS syndrome that had most of the typical features of POEMS, except that organomegaly only involved the heart. The patient's multiple clinical manifestations, including cardiomyopathy, improved with chemotherapy, which is characteristic of POEMS syndrome. However, cardiomegaly or cardiomyopathy have not previously been described with POEMS. The present case suggests that cardiomegaly and cardiomyopathy may be added to the organomegaly in POEMS.
authors.affiliation: Department of Medicine, Evaston Hospital, McGaw Medical Center of Northwestern University, Illinois.
authors.forename: T
authors.initials: T
authors.lastname: Tanus
authors.forename: H J
authors.initials: HJ
authors.lastname: Miller
mesh_terms: D006332:Cardiomegaly / Q000209:etiology*; D002311:Cardiomyopathy, Dilated / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D016878:POEMS Syndrome / Q000150:complications* / Q000453:epidemiology