Laparoscopic removal of dysgenetic gonads containing a gonadoblastoma in a patient with Swyer syndrome.
Dysgenetic streak gonads were removed laparoscopically from a phenotypic female with Swyer syndrome (ie, XY karyotype, sexual infantilism, primary amenorrhea, and müllerian structures). Pathologic examination revealed a small (3 mm) gonadoblastoma in one of her gonads without evidence of malignant transformation. The patient tolerated the procedure well and was back at work the next day. We propose that laparoscopy is a safe, cost-effective, and simple procedure to perform on individuals requiring prophylactic gonadectomy for the prevention of neoplasia.
Wilson
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Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas.
Vuitch
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Carr
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D000293:Adolescent; D004407:Dysgerminoma / Q000150:complications / Q000473:pathology / Q000601:surgery*; D005260:Female; D006061:Gonadal Dysgenesis, 46,XY / Q000150:complications*; D006801:Humans; D010535:Laparoscopy; D010051:Ovarian Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D010053:Ovary / Q000002:abnormalities