title: The relevance of a staging laparotomy for Hodgkin's disease in India.
abstract: A retrospective analysis of 328 cases of Hodgkin's Disease (HD) subjected to a staging laparotomy at the Tata Memorial Hospital, Bombay, India, from 1974 to 1986 was undertaken to assess its relevance to our setup. Eighty percent of the patients were from clinical stages (CS) I and II, 38% with lymphocyte predominance (LP), and 41% with mixed cellularity (MC) histologies. Staging laparotomy was positive in 60% cases overall, including 50% from CS IA and IIA, 68% from CS IB and IIB, and 53% and 67%, respectively, from LP and MC histologies. Splenic involvement was seen in 54% cases. Operative complications were encountered in 2% of cases and deaths in two cases only. In view of the high propensity for abdominal spread, only selected CS IA and IIA cases would merit a staging laparotomy within which, nearly 50% cases with a negative yield could be offered radical segmental irradiation alone for cure. The majority of our patients would, however, require combination therapy.
authors.affiliation: Department of Radiation Oncology, Tata Memorial Hospital, Bombay, India.
authors.forename: K A
authors.initials: KA
authors.lastname: Dinshaw
authors.forename: S C
authors.initials: SC
authors.lastname: Pande
authors.forename: S K
authors.initials: SK
authors.lastname: Shrivastava
authors.forename: M A
authors.initials: MA
authors.lastname: Gonsalves
authors.forename: S H
authors.initials: SH
authors.lastname: Advani
authors.forename: R
authors.initials: R
authors.lastname: Gopal
authors.forename: S S
authors.initials: SS
authors.lastname: Shrikhande
authors.forename: L J
authors.initials: LJ
authors.lastname: Desouza
authors.forename: P
authors.initials: P
authors.lastname: Jagannath
authors.forename: P B
authors.initials: PB
authors.lastname: Desai
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D002648:Child; D005260:Female; D006689:Hodgkin Disease / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007813:Laparotomy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012189:Retrospective Studies; D015996:Survival Rate; D014057:Tomography, X-Ray Computed