title: Minimum number of pneumococci required for capsular antigen to be detectable by latex agglutination.
abstract: Forty-eight strains of Streptococcus pneumoniae were tested in vitro to determine the minimum number required for pneumococcal capsular antigen to be detectable by latex agglutination. It was found that 10(6) to 10(7) microorganisms per ml were needed and that antigen remained detectable even when viable pneumococci could no longer be demonstrated.
authors.affiliation: Regional Public Health Laboratory, University Hospital, Groningen, The Netherlands.
authors.forename: Y
authors.initials: Y
authors.lastname: Holloway
authors.forename: W G
authors.initials: WG
authors.lastname: Boersma
authors.forename: H
authors.initials: H
authors.lastname: Kuttschrütter
authors.forename: J A
authors.initials: JA
authors.lastname: Snijder
mesh_terms: D000942:Antigens, Bacterial / Q000032:analysis*; D001431:Bacteriological Techniques; D015169:Colony Count, Microbial; D005069:Evaluation Studies as Topic; D006801:Humans; D007841:Latex Fixation Tests; D011135:Polysaccharides, Bacterial / Q000032:analysis / Q000276:immunology; D013296:Streptococcus pneumoniae / Q000276:immunology / Q000302:isolation & purification*
chemical_list: D000942:Antigens, Bacterial; D011135:Polysaccharides, Bacterial