title: Newly observed binding mode in pancreatic ribonuclease.
abstract: Dinucleotides containing guanine, when soaked into crystals of bovine pancreatic ribonuclease, have been found to bind in an unexpected manner, quite unlike interpretations of earlier X-ray diffraction studies. This finding has prompted a reexamination of three mononucleotide-RNase complexes from this laboratory resulting in a re-interpretation of the complex that involved a guanine mononucleotide.
authors.affiliation: Crystallography Department, Birkbeck College, University of London, U.K.
authors.forename: C F
authors.initials: CF
authors.lastname: Aguilar
authors.forename: P J
authors.initials: PJ
authors.lastname: Thomas
authors.forename: A
authors.initials: A
authors.lastname: Mills
authors.forename: D S
authors.initials: DS
authors.lastname: Moss
authors.forename: R A
authors.initials: RA
authors.lastname: Palmer
mesh_terms: D001665:Binding Sites; D012259:Ribonuclease, Pancreatic / Q000737:chemistry / Q000378:metabolism*; D014961:X-Ray Diffraction
chemical_list: D012259:Ribonuclease, Pancreatic