[Detection of intrahepatic lipids by 1H-MRS--studies by breath-holding & 1 cm3 VOI].
The authors performed 1H-MR spectroscopy (MRS) to depict lipids in the liver of 10 healthy volunteers. Spectra were obtained by a 1.5 T-MR unit, with STEAM from 1 x 1 x 1 cm3 VOI. Lipid peaks were depicted in 7 of the 10 volunteers by breath-holding 1H-MRS study, while in only 4 on normal breathing. The existence of lipids could not be depicted through chemical shift imaging adopting in-phase & opposed images. This suggests a clinical utility of 1H-MRS, particularly through breath-holding studies, in depicting lipids from 1 x 1 x 1 cm3 VOI in the liver in vivo.
Choji
T
T
Department of Radiology, School of Medicine, Yamaguchi University.
Honjou
K
K
Suda
H
H
Hatanaka
M
M
Sasai
K
K
Homma
Y
Y
Itoh
K
K
Suga
K
K
Nakanishi
T
T
Kimura
T
T
D006801:Humans; D050356:Lipid Metabolism; D008099:Liver / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D012016:Reference Values; D012119:Respiration / Q000502:physiology*