title: [A case of repetitive monomorphic ventricular tachycardia].
abstract: We present a case treated with aprindine and metoprolol combined with a DDD type pacemaker for repetitive monomorphic ventricular tachycardia. A 50-year-old man was admitted because of palpitation and near syncope attack. Electrocardiogram showed repetitive monomorphic ventricular tachycardias (RBBB LAD type) and R-R interval of about 440 msec and I degree A-V block in sinus rhythm. Electrophysiologic study disclosed that overdrive pacing in HRA suppressed ventricular tachycardias. Left ventriculography revealed a dilated left ventricular and decreased contractility. Antiarrhythmic agents such as quinidine sulfate, procainamide, disopyramide, mexiletine, lidocaine and propranolol were not effective. But, the combination of propranolol and aprindine decreased the rate of the ventricular tachycardia. With aprindine 60 mg/day and metoprolol 60 mg/day combined with the atrioventricular sequential pacing at 85/min, ventricular tachycardia completely disappeared.
authors.affiliation: 4th Department of Internal Medicine, Jikei University School of Medicine.
authors.forename: O
authors.initials: O
authors.lastname: Kurusu
authors.forename: S
authors.initials: S
authors.lastname: Kudou
authors.forename: J
authors.initials: J
authors.lastname: Nomoto
authors.forename: T
authors.initials: T
authors.lastname: Tanoiri
authors.forename: Y
authors.initials: Y
authors.lastname: Tokuhisa
authors.forename: Y
authors.initials: Y
authors.lastname: Kubouchi
authors.forename: T
authors.initials: T
authors.lastname: Sanada
authors.forename: C
authors.initials: C
authors.lastname: Komatsu
authors.forename: T
authors.initials: T
authors.lastname: Okamura
mesh_terms: D001073:Aprindine / Q000008:administration & dosage*; D002304:Cardiac Pacing, Artificial; D002312:Cardiomyopathy, Hypertrophic / Q000150:complications; D004359:Drug Therapy, Combination; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008790:Metoprolol / Q000008:administration & dosage*; D008875:Middle Aged; D012008:Recurrence; D013610:Tachycardia / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*
chemical_list: D001073:Aprindine; D008790:Metoprolol