title: Meningeal melanocytoma: magnetic resonance imaging characteristics and pathological features. Case report.
abstract: A case of meningeal melanocytoma at the foramen magnum is reported in a 62-year-old man. Magnetic resonance (MR) imaging revealed characteristic signal patterns: homogeneous high intensity on the T1-weighted image and low intensity on the T2-weighted image. Light microscopy showed a histological appearance similar to that of melanotic meningioma. The ultrastructural features of the neoplastic cells were compatible with those of melanocytes, but they contained no features of arachnoidal cells. Immunohistochemical bromodeoxyuridine study revealed low proliferative activity among the neoplastic cells. The MR appearance and pathological features in this rare case of meningeal melanocytoma are demonstrated and discussed.
authors.affiliation: Department of Neurological Surgery, Wakayama Medical College, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Uematsu
authors.forename: S
authors.initials: S
authors.lastname: Yukawa
authors.forename: H
authors.initials: H
authors.lastname: Yokote
authors.forename: T
authors.initials: T
authors.lastname: Itakura
authors.forename: S
authors.initials: S
authors.lastname: Hayashi
authors.forename: N
authors.initials: N
authors.lastname: Komai
mesh_terms: D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008545:Melanoma / Q000175:diagnosis / Q000473:pathology*; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000473:pathology*; D008875:Middle Aged; D014057:Tomography, X-Ray Computed