Application of models to determination of nutrient requirements: experimental techniques employing tracers.
This paper concerns some issues involved in the design of tracer experiments for the development of whole-body compartmental models of nutrient metabolism. It focuses on tracer administration protocol, use of multiple tracers, sampling strategy, measurement types and experiment duration in a pragmatic approach to obtaining data suitable for analysis and interpretation with use of models.
Ramberg
C F
CF
Department of Clinical Studies, University of Pennsylvania School of Veterinary Medicine, Kennett Square 19348.
Krishnamurti
C R
CR
Peter
D
D
Wolff
J E
JE
Boston
R C
RC
D000818:Animals; D006801:Humans; D007554:Isotopes; D007700:Kinetics; D008433:Mathematics; D008954:Models, Biological; D009751:Nutritional Requirements
D007554:Isotopes