[Beta-thromboglobulin levels and atherosclerosis. Its relationship with the presence of risk factors].
In order to evaluate whether plasma beta-thromboglobulin (as a marker of the degree of platelet function) in patients presenting clinically evident atherosclerosis is related to the presence or absence of different risk factors (smoking habit, arterial hypertension, hypercholesterolemia, diabetes, hypertriglyceridemia, obesity, hyperuricemia, alcoholism), 40 patients have been studied in whom mean beta-thromboglobulin levels was 54 +/- 25.56 ng/ml, which is very superior to levels considered normal. However, the presence of one or more risk factors did not lead to significant variations in b-thromboglobulin concentrations, and no differences were found either when each risk factor was considered separately. The positive correlation (r = 0.98; p less than 0.01) between beta-thromboglobulin and apo B levels is highlighted. The results suggest that platelet hyperfunction seems to be due to a greater extent to the atherosclerotic process rather than to the existence of a particular risk factor.
Millán Núñez-Cortés
J
J
Departamento de Medicina, Facultad de Medicina, Universidad de Cádiz.
Marchena
M J
MJ
Lorenzo
A
A
Mangas
A
A
García Rojas
J F
JF
García Calzado
M C
MC
D000368:Aged; D000437:Alcoholism / Q000150:complications; D001055:Apolipoproteins B / Q000097:blood; D001161:Arteriosclerosis / Q000097:blood* / Q000209:etiology; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D008055:Lipids / Q000097:blood; D008297:Male; D009765:Obesity / Q000150:complications; D012307:Risk Factors; D012907:Smoking; D014527:Uric Acid / Q000097:blood; D001620:beta-Thromboglobulin / Q000032:analysis*
D001055:Apolipoproteins B; D008055:Lipids; D001620:beta-Thromboglobulin; D014527:Uric Acid
Niveles de beta-tromboglobulina y aterosclerosis. Su relación con la presencia de factores de riesgo.