Triiodothyronine potentiation of fluoxetine in depressed patients.
Triiodothyronine (T3) has been shown to augment the therapeutic effect of tricyclic antidepressants as well as monoamine oxidase inhibitors. In this report, three cases of T3 potentiation of the antidepressant effect of fluoxetine are described. The results suggest that T3 augmentation may be effective with a wide range of antidepressants.
Joffe
R T
RT
Department of Psychiatry, Clarke Institute of Psychiatry University of Toronto, Ontario.
D000328:Adult; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005260:Female; D005473:Fluoxetine / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014284:Triiodothyronine / Q000008:administration & dosage / Q000627:therapeutic use*
D005473:Fluoxetine; D014284:Triiodothyronine