title: Frequency of the delta F508 deletion and G551D, R553X and G542X mutations in Yugoslav CF patients.
abstract: A study was undertaken to find the frequency of the delta F508 deletion and those of the G551D, R553X and G524X mutations among the mainly Slavic population of Serbia, Bosnia, Herzegovina, and Montenegro and compare the frequencies determined with those in other European populations. The delta F508 mutation was found to account for about 70% of CF genes in central Jugoslavia, where its frequency is significantly higher than elsewhere in Southern European populations.
authors.affiliation: Institute of Molecular Genetics and Genetic Engineering, Belgrade, Yugoslavia.
authors.forename: B B
authors.initials: BB
authors.lastname: Dabović
authors.forename: D
authors.initials: D
authors.lastname: Radojković
authors.forename: P
authors.initials: P
authors.lastname: Minić
authors.forename: J
authors.initials: J
authors.lastname: Savić
authors.forename: A
authors.initials: A
authors.lastname: Savić
mesh_terms: D002872:Chromosome Deletion; D003550:Cystic Fibrosis / Q000235:genetics*; D005787:Gene Frequency; D006801:Humans; D009154:Mutation; D015022:Yugoslavia