title: Urolithiasis in childhood: metabolic evaluation.
abstract: In order to determine metabolic disorders in children with urolithiasis, 50 patients with urinary calculi were studied. Abdominal pain and/or haematuria were the most predominant symptoms. Surgical procedures were required in 22% of these children and urinary tract infection was observed in 34% of this group. Only 2 children had anatomical malformations of the urinary tract. Absorptive hypercalciuria (32%), renal hypercalciuria (34%) and uric acid hyperexcretion (24%) were the most common metabolic abnormalities in these children. We were unable to find an underlying metabolic abnormality in only 14% of the patients. These data suggest that appropriate metabolic study will allow rational management of children with urinary stones.
authors.affiliation: Department of Medicine, Escola Paulista of Medicina, São Paulo, Brazil.
authors.forename: H C
authors.initials: HC
authors.lastname: Perrone
authors.forename: D R
authors.initials: DR
authors.lastname: dos Santos
authors.forename: M V
authors.initials: MV
authors.lastname: Santos
authors.forename: M E
authors.initials: ME
authors.lastname: Pinheiro
authors.forename: J
authors.initials: J
authors.lastname: Toporovski
authors.forename: O L
authors.initials: OL
authors.lastname: Ramos
authors.forename: N
authors.initials: N
authors.lastname: Schor
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003404:Creatinine / Q000378:metabolism; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000378:metabolism; D007223:Infant; D008297:Male; D014527:Uric Acid / Q000378:metabolism; D014545:Urinary Calculi / Q000209:etiology / Q000378:metabolism*; D014552:Urinary Tract Infections / Q000378:metabolism
chemical_list: D014527:Uric Acid; D003404:Creatinine