title: Fatal necrotizing fasciitis of dental origin.
abstract: Necrotizing fasciitis is a potentially fatal, acute bacterial infection characterized by extensive fascial and subcutaneous tissue necrosis. Four factors that contribute significantly to the morbidity and mortality of necrotizing fasciitis are: 1) delayed treatment, due to difficulty in recognizing the condition; 2) inappropriate treatment; 3) host debilitation; and 4) a polymicrobial infection.
authors.affiliation: Faculty of Dentistry, University of Manitoba, Winnipeg.
authors.forename: A A
authors.initials: AA
authors.lastname: Stoykewych
authors.forename: W A
authors.initials: WA
authors.lastname: Beecroft
authors.forename: A G
authors.initials: AG
authors.lastname: Cogan
mesh_terms: D000328:Adult; D001442:Bacteroides Infections / Q000188:drug therapy / Q000209:etiology; D002177:Candidiasis / Q000188:drug therapy / Q000209:etiology; D002439:Cefotaxime / Q000627:therapeutic use; D002981:Clindamycin / Q000627:therapeutic use; D003023:Cloxacillin / Q000627:therapeutic use; D005208:Fasciitis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D005260:Female; D005491:Focal Infection, Dental; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use; D009102:Multiple Organ Failure; D009334:Neck Muscles; D009336:Necrosis; D010400:Penicillin G / Q000627:therapeutic use; D010482:Periapical Abscess / Q000150:complications; D012772:Shock, Septic / Q000188:drug therapy / Q000209:etiology; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000209:etiology; D013290:Streptococcal Infections / Q000188:drug therapy / Q000209:etiology; D015163:Superinfection
chemical_list: D005839:Gentamicins; D008795:Metronidazole; D002981:Clindamycin; D002439:Cefotaxime; D003023:Cloxacillin; D010400:Penicillin G