title: Escherichia coli mutant Y16 is a double mutant carrying thermosensitive ftsH and ftsI mutations.
abstract: The Escherichia coli mutant Y16, which shows thermosensitive colony formation and filamentation with reduced amounts of penicillin-binding protein 3 (PBP3), has mutations in the ftsI gene encoding PBP3 and in the ftsH gene. The ftsI mutation markedly reduces the amount of PBP3 at 42 degrees C, whereas the amount of the ftsH single mutant is slightly reduced.
authors.affiliation: Institute of Cell and Molecular Biology, University of Edinburgh, Scotland.
authors.forename: K J
authors.initials: KJ
authors.lastname: Begg
authors.forename: T
authors.initials: T
authors.lastname: Tomoyasu
authors.forename: W D
authors.initials: WD
authors.lastname: Donachie
authors.forename: M
authors.initials: M
authors.lastname: Khattar
authors.forename: H
authors.initials: H
authors.lastname: Niki
authors.forename: K
authors.initials: K
authors.lastname: Yamanaka
authors.forename: S
authors.initials: S
authors.lastname: Hiraga
authors.forename: T
authors.initials: T
authors.lastname: Ogura
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D002455:Cell Division; D004926:Escherichia coli / Q000235:genetics*; D005798:Genes, Bacterial; D005816:Genetic Complementation Test; D009154:Mutation; D013696:Temperature
chemical_list: D001426:Bacterial Proteins