title: Siderophore production of Klebsiella species isolated from different sources.
abstract: A total of 481 Klebsiella pneumoniae and K. oxytoca strains isolated from different sources was examined for siderophore production. Screening for siderophore secretion by chrome azurol S agar revealed that 475 strains (98.8%) produced siderophores. The isolates were further investigated for synthesis of enterochelin and aerobactin by means of specific bioassays. Almost all Klebsiella strains (99.4%) excreted enterochelin. Aerobactin production, however, was rarely observed among K. pneumoniae (6%) and K. oxytoca (4%) isolates. The incidence of aerobaction-positive strains was similar in clinical, fecal, and environmental isolates. These results suggest that the aerobactin system does not represent a major mechanism of iron supply in Klebsiella spp.
authors.affiliation: Institute of Medical Microbiology, University of Kiel.
authors.forename: R
authors.initials: R
authors.lastname: Podschun
authors.forename: A
authors.initials: A
authors.lastname: Fischer
authors.forename: U
authors.initials: U
authors.lastname: Ullmann
mesh_terms: D004758:Enterobactin / Q000378:metabolism; D005243:Feces / Q000382:microbiology; D006801:Humans; D006877:Hydroxamic Acids / Q000378:metabolism; D007476:Ionophores / Q000378:metabolism*; D007502:Iron Chelating Agents / Q000378:metabolism*; D007709:Klebsiella / Q000378:metabolism*; D007711:Klebsiella pneumoniae / Q000378:metabolism*; D012722:Sewage; D017262:Siderophores
chemical_list: D006877:Hydroxamic Acids; D007476:Ionophores; D007502:Iron Chelating Agents; D012722:Sewage; D017262:Siderophores; C031819:aerobactin; D004758:Enterobactin