title: [Sclerotherapy of the internal saphenous vein: comparison between the trombovar protocol and the trombovar-iodine protocol].
abstract: Sclérosing injections of the long saphenous vein involve different protocols concerning technique as well as the sclerosing fluids and doses used. This retrospective study involved comparison of two groups of patients treated during successive periods on the basis of a protocol consisting of 3 per cent Trombovar at doses increasing progressively up to a maximum of 6 and another protocole as follows: 3 per cent Trombovar, 1 ml; 3 per cent Trombovar 2 ml; 8 per cent Variglobine 2 ml; 12% Variglobine 2 ml; 12 per cent Variglobine 3 ml; "Overdose" (12 per cent Variglobine 6 ml + 3 per cent Trombovar 6 ml, i.e. 2-4 ml as divided doses. Patients were seen for follow-up evaluation by continuous wave Doppler after six months and two years. The first protocole, with a mean follow-up of 11.5 months, was associated with a 40 per cent recurrence rate. The rate for the second, with a mean follow-up of 13.5 months, was 15.87 per cent. The difference between these figures was statistically very significant (p approximately 0.001). The largest amounts of sclerosing fluid provided lower percentage recurrence rates compared relatively small amounts.
authors.affiliation: Centro Studi Malattie Vascolari J.F. Merlen, Frosinone, Italie.
authors.forename: S
authors.initials: S
authors.lastname: Bilancini
authors.forename: M
authors.initials: M
authors.lastname: Lucchi
authors.forename: S
authors.initials: S
authors.lastname: Tucci
mesh_terms: D001592:Benzyl Alcohols / Q000008:administration & dosage / Q000627:therapeutic use*; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D006801:Humans; D007454:Iodides / Q000008:administration & dosage / Q000627:therapeutic use*; D007558:Italy / Q000453:epidemiology; D012008:Recurrence; D012189:Retrospective Studies; D012501:Saphenous Vein; D015911:Sclerotherapy / Q000379:methods / Q000592:standards*; D012964:Sodium / Q000008:administration & dosage / Q000627:therapeutic use*; D012981:Sodium Tetradecyl Sulfate / Q000008:administration & dosage / Q000627:therapeutic use*; D014463:Ultrasonography; D014648:Varicose Veins / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000628:therapy*
chemical_list: D001592:Benzyl Alcohols; D004338:Drug Combinations; D007454:Iodides; C053468:Varigloban; D012964:Sodium; D012981:Sodium Tetradecyl Sulfate
vernacular_title: La sclérose de la saphène interne: comparaison entre le protocole trombovar et le protocole trombovar-iode.