Use of tetracycline and niacinamide for treatment of autoimmune skin disease in 31 dogs.
A combination of niacinamide and tetracycline was used to treat 31 dogs with various autoimmune skin diseases (discoid lupus erythematosus, pemphigus foliaceus, pemphigus erythematosus, and bullous pemphigoid). Of the 20 dogs with discoid lupus erythematosus, 70% had excellent or good response to treatment. Serious side effects were not noticed in any dog.
White
S D
SD
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523.
Rosychuk
R A
RA
Reinke
S I
SI
Paradis
M
M
D000818:Animals; D001327:Autoimmune Diseases / Q000188:drug therapy / Q000662:veterinary*; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D004338:Drug Combinations; D005260:Female; D008179:Lupus Erythematosus, Discoid / Q000188:drug therapy / Q000662:veterinary; D009536:Niacinamide / Q000627:therapeutic use*; D010391:Pemphigoid, Bullous / Q000188:drug therapy / Q000662:veterinary; D010392:Pemphigus / Q000188:drug therapy / Q000662:veterinary*; D012871:Skin Diseases / Q000188:drug therapy / Q000662:veterinary*; D013752:Tetracycline / Q000627:therapeutic use*
D004338:Drug Combinations; D009536:Niacinamide; D013752:Tetracycline