Thymic rebound following successful chemotherapy of B-lymphoma in an adolescent boy.
Four months after termination of successful chemotherapy for epipharyngeal B-non-Hodgkin lymphoma, an enlarging anterior mediastinal mass was discovered in a 15-year-old boy. There was no other suspicion of tumour recurrence. A simple thymic rebound was likely and a conservative management was chosen. Follow up for more than 12 months was uneventful. The frequency of thymic hyperplasia after termination of chemotherapy is discussed. It is a benign immunological rebound phenomenon and does not require operative intervention.
Leibundgut
K
K
Division of Haematology and Oncology, Universitäts-Kinderspital Zürich, Switzerland.
Willi
U
U
Plüss
H J
HJ
D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001215:Asparaginase / Q000627:therapeutic use; D003630:Daunorubicin / Q000627:therapeutic use; D006801:Humans; D016393:Lymphoma, B-Cell / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008297:Male; D010610:Pharyngeal Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011241:Prednisone / Q000627:therapeutic use; D013952:Thymus Hyperplasia / Q000000981:diagnostic imaging / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D014750:Vincristine / Q000627:therapeutic use
D014750:Vincristine; D001215:Asparaginase; D011241:Prednisone; D003630:Daunorubicin