Birthweight and obstetric complications in schizophrenic twins.
Birthweight and obstetric complications were registered retrospectively in 24 monozygotic (MZ) twin pairs. Sixteen pairs were discordant and 8 pairs were concordant for DSM-III-R schizophrenia. There was no significant intrapair difference in birthweight between the 2 groups of MZ twins. Prematurity was more often observed in the discordant pairs, but neither differences in prematurity nor differences in obstetric complications between the concordant and discordant twins reached significance. No difference in respect of family history of schizophrenia between the 2 groups of MZ twins was found. In the discordant pairs, no significant difference between the schizophrenic twin and the nonschizophrenic co-twin was observed regarding birth order, birthweight or physical condition at birth.
Onstad
S
S
Department of Psychiatry, University of Oslo, Norway.
Skre
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I
Torgersen
S
S
Kringlen
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E
D000328:Adult; D001724:Birth Weight / Q000235:genetics*; D001925:Brain Damage, Chronic / Q000175:diagnosis / Q000209:etiology / Q000235:genetics*; D004200:Diseases in Twins / Q000235:genetics* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D019965:Neurocognitive Disorders / Q000175:diagnosis / Q000209:etiology / Q000235:genetics*; D007744:Obstetric Labor Complications / Q000175:diagnosis*; D011247:Pregnancy; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis / Q000209:etiology / Q000235:genetics*; D012565:Schizophrenic Psychology; D014430:Twins, Monozygotic / Q000235:genetics / Q000523:psychology