title: Reversible myocardial impairment in the Churg-Strauss syndrome: report of a case.
abstract: Heart disease is a major cause of morbidity and mortality in the Churg-Strauss syndrome. However, few clinical follow-ups have been published. In this case report, in which the diagnosis of Churg-Strauss syndrome was made based on histologic criteria and clinical features, heart failure with globally depressed left ventricular function was present. Aggressive therapy (prednisone and cyclophosphamide) was instituted. In the follow-up a prompt clinical response and eventual recovery of the indices of cardiac function as evaluated by echocardiography and radionuclide ventriculography were observed.
authors.affiliation: 2. Division di Medicina Generale, Spedali Civili di Brescia, Italy.
authors.forename: G P
authors.initials: GP
authors.lastname: Balestrieri
authors.forename: U
authors.initials: U
authors.lastname: Valentini
authors.forename: B
authors.initials: B
authors.lastname: Cerudelli
authors.forename: S
authors.initials: S
authors.lastname: Spandrio
authors.forename: E
authors.initials: E
authors.lastname: Renaldini
mesh_terms: D000328:Adult; D009202:Cardiomyopathies / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D015267:Churg-Strauss Syndrome / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D003520:Cyclophosphamide / Q000627:therapeutic use; D004452:Echocardiography; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D011239:Prednisolone / Q000627:therapeutic use; D011877:Radionuclide Imaging; D016277:Ventricular Function, Left / Q000502:physiology
chemical_list: D003520:Cyclophosphamide; D011239:Prednisolone