[Studies on the active constituents of Anemarrhena asphodeloides bunge].
From the ethanol extract of the Anemarrhena asphodeloides Buge (Liliaceae), a new steroidal suponin anemarsaponin B and two known saponins anemarsaponin A1 and A2 were isolated. On the basis of chemical evidences and spectral analysis (UV, IR, EI-MS, FAB-MS, 1H-NMR and 13C-NMR), the structure of anemarsaponin B was elucidated as 26-O-beta-D-glucopyranosylfurost-20(22)-ene-3 beta,26-diol-3-O-beta-D- glucopyranosyl(1----2)-beta-D-galactopyranoside. Preliminary pharmacological tests showed that anemarsaponin B could inhibit PAF-induced rabbit platelet aggregation in vitro.
Dong
J X
JX
College of Pharmacy, Second Military Medical Universlity, Shanghai.
Han
G Y
GY
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D010974:Platelet Aggregation / Q000187:drug effects; D010975:Platelet Aggregation Inhibitors / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D011817:Rabbits; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014315:Triterpenes
D004365:Drugs, Chinese Herbal; D010975:Platelet Aggregation Inhibitors; D012503:Saponins; D014315:Triterpenes; C073427:anemarsaponin B