Loss of radiogallium from lymphoma after initiation of chemotherapy.
A man with a high-grade lymphoma had radiogallium imaging at 48 hours postinjection, revealing three distinct sites of uptake (neck and thorax). Unknown to the authors, the patient was given cytoxan, vincristine, and prednisone intravenously 27 hours after radiogallium administration. The images at 120 hours showed markedly reduced radiogallium activity at all three sites. Possible reasons for the loss of radiogallium from the tumor sites were presented.
Dambro
T J
TJ
Department of Nuclear Medicine, University of Connecticut Health Center, Farmington 06030.
Slavin
J D
JD
Epstein
N F
NF
Weiner
R E
RE
Spencer
R P
RP
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002951:Citrates; D019343:Citric Acid; D003520:Cyclophosphamide / Q000008:administration & dosage; D005710:Gallium Radioisotopes; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy; D006801:Humans; D016400:Lymphoma, Large-Cell, Immunoblastic / Q000000981:diagnostic imaging* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage; D011877:Radionuclide Imaging; D013899:Thoracic Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy; D013997:Time Factors; D014750:Vincristine / Q000008:administration & dosage
D002951:Citrates; D005710:Gallium Radioisotopes; D019343:Citric Acid; D014750:Vincristine; D003520:Cyclophosphamide; D011241:Prednisone