title: Massive small bowel resection in neonates--is weaning from parenteral nutrition the final goal?
abstract: Eight surviving cases from an original 15 pediatric patients who underwent massive small bowel resection during their neonatal period were reviewed for a period of 2-19 years to assess long-term prognosis. the primary diseases were congenital intestinal atresia in 6 cases and midgut volvulus in 2. The length of the residual small intestine ranged from 27-75 cm and the ileocaecal valve had been resected in 3 cases. All cases were able to be weaned from parenteral nutrition and at present, 6 of the children can tolerate normal meals but 2 are still receiving enteral nutrition, in the form of a low residue diet at home. Near normal somatic growth was achieved in the most recent 5 cases who received intensive nutritional treatment in the immediate postoperative period, whereas 3 who did not receive nutritional management exhibited growth retardation. The D-Xylose absorption test revealed gradual improvement and finally normal absorption in all except one case with the shortest remaining intestine (27 cm). However, the fat absorption test revealed abnormal absorption in cases with a residual intestine of less than 45 cm. Late metabolic complications such as renal calculi, cholelithiasis and pathologic fractures were encountered in 3 cases.
authors.affiliation: Department of Pediatric Surgery, Osaka University Medical School, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Matsuo
authors.forename: R
authors.initials: R
authors.lastname: Nezu
authors.forename: A
authors.initials: A
authors.lastname: Kubota
authors.forename: M
authors.initials: M
authors.lastname: Fukuzawa
authors.forename: K
authors.initials: K
authors.lastname: Imura
authors.forename: S
authors.initials: S
authors.lastname: Kamata
authors.forename: Y
authors.initials: Y
authors.lastname: Takagi
authors.forename: A
authors.initials: A
authors.lastname: Okada
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006128:Growth; D006801:Humans; D007080:Ileocecal Valve / Q000601:surgery; D007223:Infant; D007408:Intestinal Absorption; D007409:Intestinal Atresia / Q000503:physiopathology / Q000601:surgery / Q000628:therapy*; D007415:Intestinal Obstruction / Q000503:physiopathology / Q000601:surgery / Q000628:therapy; D007421:Intestine, Small / Q000601:surgery; D008297:Male; D010289:Parenteral Nutrition, Total; D011183:Postoperative Complications; D012778:Short Bowel Syndrome / Q000503:physiopathology / Q000601:surgery / Q000628:therapy*; D013997:Time Factors