New artificial connective matrix-like structure made of elastin solubilized peptides and collagens: elaboration, biochemical and structural properties.
Several improvements of the basic reaction between elastin peptides and type III collagen, specially the addition of heparan sulphate proteoglycans, are presented. The consequent elaboration of either cell culture support or membranes are described and illustrated by scanning electron microscopy. The material produced possesses composition, very well organized lamellar structure and some properties quite close to natural membranes such as subendothelial tissue.
Lefebvre
F
F
U. 306-INSERM, Université de Bordeaux II, France.
Gorecki
S
S
Bareille
R
R
Amedee
J
J
Bordenave
L
L
Rabaud
M
M
D001672:Biocompatible Materials; D003094:Collagen / Q000737:chemistry; D003238:Connective Tissue / Q000737:chemistry; D004549:Elastin / Q000737:chemistry; D005109:Extracellular Matrix / Q000737:chemistry*; D016326:Extracellular Matrix Proteins / Q000737:chemistry; D006801:Humans; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D010455:Peptides / Q000737:chemistry; D011509:Proteoglycans / Q000737:chemistry; D012995:Solubility
D001672:Biocompatible Materials; D016326:Extracellular Matrix Proteins; D010455:Peptides; D011509:Proteoglycans; D003094:Collagen; D004549:Elastin