title: A case of destructive polyarthropathy in a 17-year-old youth following pefloxacin treatment.
abstract: Joint and muscle pain have been reported with quinolones; however, arthropathies induced by quinolones do not result in erosive changes in humans, although such changes have occurred in animal studies. We report an unusual case of destructive polyarthropathy in a 17-year-old boy after treatment with pefloxacin 800 mg/day for 3 months. Pefloxacin may have accentuated the cartilage damage in this case, even if an underlying joint disease could not be excluded.
authors.affiliation: Department of Rheumatology, Hôpital Henri-Mondor, Créteil, France.
authors.forename: X
authors.initials: X
authors.lastname: Chevalier
authors.forename: E
authors.initials: E
authors.lastname: Albengres
authors.forename: M C
authors.initials: MC
authors.lastname: Voisin
authors.forename: J P
authors.initials: JP
authors.lastname: Tillement
authors.forename: B
authors.initials: B
authors.lastname: Larget-Piet
mesh_terms: D000293:Adolescent; D001064:Appendicitis / Q000601:surgery; D001922:Brain Abscess / Q000188:drug therapy; D006801:Humans; D007592:Joint Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging; D008297:Male; D015366:Pefloxacin / Q000009:adverse effects*; D011183:Postoperative Complications / Q000188:drug therapy*; D011859:Radiography
chemical_list: D015366:Pefloxacin