HLA-DR genes are silenced in human trophoblasts and stimulation of signal transduction pathways does not circumvent interferon-gamma unresponsiveness.
Peyman
J A
JA
Department of Surgery, Yale University School of Medicine, New Haven, CT 06510.
Nelson
P J
PJ
Hammond
G L
GL
D000001:Calcimycin / Q000494:pharmacology; D002772:Cholera Toxin / Q000494:pharmacology*; D005576:Colforsin / Q000494:pharmacology; D005260:Female; D005802:Genes, MHC Class II / Q000187:drug effects; D006684:HLA-DR Antigens / Q000235:genetics*; D006801:Humans; D007371:Interferon-gamma / Q000494:pharmacology*; D015759:Ionomycin / Q000494:pharmacology; D010920:Placenta / Q000276:immunology; D010972:Platelet Activating Factor / Q000494:pharmacology; D011247:Pregnancy; D011971:Receptors, Immunologic / Q000187:drug effects / Q000502:physiology; D017471:Receptors, Interferon; D011994:Recombinant Proteins; D015398:Signal Transduction / Q000187:drug effects*; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D014327:Trophoblasts / Q000187:drug effects / Q000276:immunology*; D010566:Virulence Factors, Bordetella / Q000494:pharmacology
D006684:HLA-DR Antigens; D010972:Platelet Activating Factor; D011971:Receptors, Immunologic; D017471:Receptors, Interferon; D011994:Recombinant Proteins; D010566:Virulence Factors, Bordetella; D005576:Colforsin; D000001:Calcimycin; D015759:Ionomycin; D007371:Interferon-gamma; D002772:Cholera Toxin; D013755:Tetradecanoylphorbol Acetate