title: Fetal monitoring in perinatal sepsis.
abstract: To evaluate the utility of conventional electronic fetal monitoring in detection of established perinatal sepsis, we conducted a case-controlled study of fetal monitor results in 18 patients delivering newborns with sepsis. Eleven of the 18 newborns (61%) demonstrated clinically reassuring fetal heart rate patterns, not significantly different from controls (p = 0.80). No pattern predictive of presumed perinatal sepsis could be identified. Obstetric factors traditionally associated with increased risk of perinatal infection, such as long duration of labor, use of internal fetal monitoring, and increased number of vaginal examinations were not significantly different from controls. Preterm rupture of membranes greater than 24 hours occurred in less than 50% of the cases. Clinical diagnosis of chorioamnionitis was established in only one third of the patients who delivered newborns with sepsis. In this study, use of conventional electronic fetal monitoring did not accurately identify newborns with presumed intrauterine infection.
authors.affiliation: University of Colorado Health Sciences Center, Denver.
authors.forename: D
authors.initials: D
authors.lastname: Day
authors.forename: J H
authors.initials: JH
authors.lastname: Ugol
authors.forename: J I
authors.initials: JI
authors.lastname: French
authors.forename: A
authors.initials: A
authors.lastname: Haverkamp
authors.forename: R E
authors.initials: RE
authors.lastname: Wall
authors.forename: J A
authors.initials: JA
authors.lastname: McGregor
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D005069:Evaluation Studies as Topic; D005260:Female; D005323:Fetal Monitoring; D006340:Heart Rate, Fetal / Q000502:physiology*; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007744:Obstetric Labor Complications / Q000453:epidemiology; D007752:Obstetric Labor, Premature / Q000453:epidemiology; D011237:Predictive Value of Tests; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D013290:Streptococcal Infections / Q000453:epidemiology*; D013292:Streptococcus agalactiae / Q000302:isolation & purification*