title: Cariostatic effect and fluoride release from a visible light-curing adhesive for bonding of orthodontic brackets.
abstract: This study was designed to investigate the cariostatic potential in vivo of a visible light-curing adhesive for the bonding of orthodontic brackets. The fluoride release of the adhesive in water and saliva was also measured. Ten orthodontic patients with premolars to be extracted participated. One bracket with Heliosit-Orthodontic (no fluoride) was positioned on the buccal surface of one premolar (control), and another bracket with Orthodontic cement VP 862 (containing fluoride) was positioned on the experimental contralateral premolar. The adhesives were cured with a Heliolux II lamp, and the teeth were extracted after 4 weeks. The patients used a fluoride toothpaste during the experiment. The mineral content of the enamel adjacent to the brackets was determined by quantitative microradiography. The fluoride release from disk-shaped plates of the fluoride adhesive was measured in water for a 6-month period and in human saliva for 24 hours. The fluoride adhesive reduced lesion depths by about 48% than the nonfluoride adhesive (P less than 0.05, t test). The largest release of fluoride from the plates in water was observable within the first week. However, a significant amount of fluoride was still released after 6 months. The fluoride release in saliva was significantly lower in human saliva at pH 7 than in water (P less than 0.01, t test). When salivary pH was lowered to 4, to mimic a cariogenic challenge, the amount of fluoride released increased up to the value measured in water. It was concluded that the regular use of fluoride toothpastes is insufficient to inhibit lesion development around orthodontic brackets.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Orthodontics, Dental Faculty, University of Oslo, Norway.
authors.forename: B
authors.initials: B
authors.lastname: Ogaard
authors.forename: F
authors.initials: F
authors.lastname: Rezk-Lega
authors.forename: J
authors.initials: J
authors.lastname: Ruben
authors.forename: J
authors.initials: J
authors.lastname: Arends
mesh_terms: D000269:Adhesives / Q000737:chemistry; D017438:Bisphenol A-Glycidyl Methacrylate; D003692:Delayed-Action Preparations; D001840:Dental Bonding; D003731:Dental Caries / Q000209:etiology / Q000517:prevention & control*; D003738:Dental Cements / Q000737:chemistry* / Q000627:therapeutic use*; D005459:Fluorides; D005460:Fluorides, Topical / Q000008:administration & dosage* / Q000032:analysis / Q000737:chemistry / Q000627:therapeutic use*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008689:Methacrylates; D008852:Microradiography; D016910:Orthodontic Brackets / Q000009:adverse effects; D011109:Polymethacrylic Acids / Q000737:chemistry; D011140:Polyurethanes; D012463:Saliva / Q000737:chemistry; D014520:Urethane / Q000737:chemistry / Q000627:therapeutic use*; D014867:Water
chemical_list: D000269:Adhesives; D003692:Delayed-Action Preparations; D003738:Dental Cements; D005460:Fluorides, Topical; D008689:Methacrylates; C073962:Orthodontic Cement VP 862; D011109:Polymethacrylic Acids; D011140:Polyurethanes; D014867:Water; C029824:urethane dimethacrylate luting resin; D014520:Urethane; D017438:Bisphenol A-Glycidyl Methacrylate; D005459:Fluorides