title: Central venous catheterization in patients with coagulopathy.
abstract: To explore the risk of bleeding complications during percutaneous central venous catheterization in patients with coagulopathy, 40 liver transplant recipients underwent 259 percutaneous central venous catheterizations. Two hundred two catheterizations were performed in patients with coagulopathy, as evidenced by their prothrombin times, activated partial thromboplastin times, and/or platelet counts. Furthermore, no attempt was made to correct these episodes of coagulopathy with medications or infusion of blood products. No serious bleeding complications occurred during the 259 catheterizations, which suggests that experienced clinicians using appropriate techniques may safely perform central venous catheterization in patients with abnormal prothrombin times, activated partial thromboplastin times, and platelet counts.
authors.affiliation: Department of General Surgery, Rush-Presbyterian-St Luke's Medical Center, Chicago, IL 60612.
authors.forename: P F
authors.initials: PF
authors.lastname: Foster
authors.forename: L R
authors.initials: LR
authors.lastname: Moore
authors.forename: H N
authors.initials: HN
authors.lastname: Sankary
authors.forename: M E
authors.initials: ME
authors.lastname: Hart
authors.forename: M K
authors.initials: MK
authors.lastname: Ashmann
authors.forename: J W
authors.initials: JW
authors.lastname: Williams
mesh_terms: D001778:Blood Coagulation Disorders / Q000097:blood / Q000453:epidemiology* / Q000209:etiology; D002405:Catheterization, Central Venous / Q000009:adverse effects* / Q000295:instrumentation / Q000379:methods; D006801:Humans; D015994:Incidence; D016031:Liver Transplantation / Q000009:adverse effects*; D010314:Partial Thromboplastin Time; D010976:Platelet Count; D011183:Postoperative Complications / Q000097:blood / Q000453:epidemiology* / Q000209:etiology; D011517:Prothrombin Time; D012189:Retrospective Studies; D012307:Risk Factors