Age- and sex-related differences in the content of prothymosin alpha in rat tissues.
Differences in the tissue content of prothymosin alpha during the early postnatal development of male and female rats are reported. Thymus and spleen have been found to contain significantly higher amounts of prothymosin alpha in the newborn and prepubertal animals, as compared to adults, whereas liver has been found to contain low levels of prothymosin alpha throughout development. These findings indicate a functional association of prothymosin alpha with the proliferating lymphoid tissues of the young rat.
Frillingos
S
S
Laboratory of Biological Chemistry, University of Ioannina Medical School, Greece.
Tsolas
O
O
D000375:Aging / Q000378:metabolism; D000818:Animals; D005260:Female; D008099:Liver / Q000254:growth & development / Q000378:metabolism; D008221:Lymphoid Tissue / Q000378:metabolism; D008297:Male; D011498:Protein Precursors / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012727:Sex Characteristics; D013154:Spleen / Q000254:growth & development / Q000378:metabolism; D013947:Thymosin / Q000031:analogs & derivatives* / Q000378:metabolism; D013950:Thymus Gland / Q000254:growth & development / Q000378:metabolism
D011498:Protein Precursors; C040782:prothymosin alpha; D013947:Thymosin