title: Evidence for high levels of androgen in peripheral plasma during postnatal development in a marsupial: the gray short-tailed opossum (Monodelphis domestica).
abstract: Plasma samples were assayed for androgen in gray short-tailed opossums (Monodelphis domestica) on the day of birth and at selected ages through adulthood. Levels of androgen in mixed-sex plasma pools of animals 4 and 8 days of age were higher than in either sex at all other ages examined. At postnatal Days 16, 30, and 60 (weaning), levels of androgen were equivalent in males and females and as high as in adult males. In both sexes, androgen levels were lower at postnatal Day 84 (juveniles) than at younger ages; after puberty, levels were significantly higher in males than in females. These findings are discussed with respect to similarities and differences between marsupials and eutherians in hormonal environment during the perinatal period and with respect to the possible role of androgens in sexual differentiation of the gray opossum brain.
authors.affiliation: Department of Psychiatry, UMDNJ-New Jersey Medical School, Newark 07103.
authors.forename: B H
authors.initials: BH
authors.lastname: Fadem
authors.forename: J D
authors.initials: JD
authors.lastname: Harder
mesh_terms: D000728:Androgens / Q000097:blood*; D000818:Animals; D000831:Animals, Newborn; D005260:Female; D008297:Male; D009893:Opossums / Q000097:blood* / Q000254:growth & development; D012727:Sex Characteristics; D012733:Sex Differentiation
chemical_list: D000728:Androgens