The complete nucleotide sequence of the gene coding for the nontoxic-nonhemagglutinin component of Clostridium botulinum type C progenitor toxin.
The structural gene for a nontoxic-nonhemagglutinin component of Clostridium botulinum type C progenitor toxin was found to exist on a 7.8 kb DNA fragment obtained from a type C phage DNA. The gene existed between the neurotoxin and hemagglutinin genes, and consisted of an 3588 bp open reading frame (1196 amino acid residues). It was speculated that this gene and the neurotoxin gene were transcribed by the same mRNA (polycistronic transcription) in C. botulinum organisms.
Tsuzuki
K
K
Department of Microbiology, Sapporo Medical College, Japan.
Kimura
K
K
Fujii
N
N
Yokosawa
N
N
Oguma
K
K
D000595:Amino Acid Sequence; D001483:Base Sequence; D001905:Botulinum Toxins / Q000235:genetics* / Q000302:isolation & purification; D003001:Cloning, Molecular; D003014:Clostridium botulinum / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics; D046911:Macromolecular Substances; D008969:Molecular Sequence Data; D012689:Sequence Homology, Nucleic Acid
D046911:Macromolecular Substances; D001905:Botulinum Toxins