title: Pre-cancerous lesions of the oesophagus in Argentina: prevalence and association with tobacco and alcohol.
abstract: The prevalence of pre-cancerous lesions of the oesophagus and their association with alcohol and tobacco were examined in an endoscopic survey carried out in La Plata, Argentina. The study included 406 subjects over 15 years of age attending several gastroenterology clinics because of various gastrointestinal symptoms. Among males, the prevalence rates of chronic oesophagitis, epithelial atrophy and dysplasia were 42%, 3.8% and 2.4% respectively, and in females these prevalences were 36%, 2.5% and 0.0%. The presence of these pre-cancerous lesions was significantly associated with alcohol drinking and tobacco smoking.
authors.affiliation: Departamento de Patología, Facultad de Ciencias Médicas de la Plata, Argentina.
authors.forename: R
authors.initials: R
authors.lastname: Castelletto
authors.forename: N
authors.initials: N
authors.lastname: Muñoz
authors.forename: N
authors.initials: N
authors.lastname: Landoni
authors.forename: A
authors.initials: A
authors.lastname: Jmelnitzky
authors.forename: M
authors.initials: M
authors.lastname: Crespi
authors.forename: P
authors.initials: P
authors.lastname: Belloni
authors.forename: N
authors.initials: N
authors.lastname: Chopita
authors.forename: S
authors.initials: S
authors.lastname: Teuchmann
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects / Q000453:epidemiology; D001118:Argentina / Q000453:epidemiology; D004938:Esophageal Neoplasms / Q000453:epidemiology* / Q000473:pathology; D004941:Esophagitis / Q000453:epidemiology / Q000473:pathology; D004945:Esophagoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011230:Precancerous Conditions / Q000453:epidemiology* / Q000473:pathology; D015995:Prevalence; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology