[A case of extraneural metastasis of medulloblastoma successfully treated with cisplatin and etoposide].
A patient who had been treated for cerebellar medulloblastoma presented progressive abdominal distension and tachypnea. Metastases of the tumor in the abdominal and thoracic cavity were confirmed by cytology. The authors treated the metastasis with a combination of intravenous administration of 20 mg/m2/day cisplatin and 60 mg/m2/day etoposide for two 5-day cycles. After chemotherapy, the patient recovered fully with time and follow-up radiological studies demonstrated no evidence of tumor recurrence. Combination chemotherapy with cisplatin and etoposide is to be considered effective for extraneural metastasis of medulloblastoma.
Kanai
H
H
Dept. of Neurosurgery, Nagoya City University Medical School, Japan.
Nagai
H
H
Mabe
H
H
Wakabayashi
S
S
Yamashita
N
N
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002528:Cerebellar Neoplasms / Q000473:pathology*; D002675:Child, Preschool; D002945:Cisplatin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D005047:Etoposide / Q000008:administration & dosage; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008527:Medulloblastoma / Q000188:drug therapy* / Q000556:secondary; D012074:Remission Induction; D013899:Thoracic Neoplasms / Q000188:drug therapy* / Q000556:secondary
D005047:Etoposide; D002945:Cisplatin