title: Orthognathic surgery in patients with Crohn's disease: a review of the pathophysiology and perioperative management.
abstract: The patient with Crohn's disease poses an interesting challenge to the oral and maxillofacial surgeon contemplating orthognathic surgery. Elective surgery should be limited to periods of disease remission. Even in a quiescent state, however, this disease requires careful perioperative management. Special attention must be paid to the patient's diet and maintenance medications. Often these patients have required long-term corticosteroid therapy, which, in addition to increasing surgical and anesthetic risk, has the potential to adversely affect bone healing. This article presents a review of the pathophysiology of Crohn's disease and discusses the perioperative and postoperative concerns associated with this disease.
authors.affiliation: University of Pittsburgh Hospitals, PA.
authors.forename: G W
authors.initials: GW
authors.lastname: Wilson
authors.forename: J M
authors.initials: JM
authors.lastname: Sisto
mesh_terms: D003424:Crohn Disease / Q000150:complications / Q000503:physiopathology*; D006801:Humans; D007430:Intraoperative Care; D009055:Mouth / Q000601:surgery*; D009059:Mouth Diseases / Q000209:etiology; D056948:Orthognathic Surgical Procedures; D011300:Preoperative Care