title: [Acute articular rheumatism: physiopathology, clinical aspects].
abstract: Acute rheumatic fever is characterized by non suppurative inflammatory lesions involving the heart, joints, subcutaneous tissues and central nervous system. It is a complication of group A streptococcal upper respiratory tract infection. The pathogenic mechanisms remain unknown although there is a general agreement as to an immunological hypothesis. Pharyngitis must be treated, even if streptococcal origin is not proved. Penicillin remains the first choice antibiotic. Epidemiological studies of all group A streptococcal serotypes isolated should be performed.
authors.affiliation: Service des maladies infectieuses et tropicales, groupe hospitalier Bichat-Claude-Bernard, Paris.
authors.forename: P
authors.initials: P
authors.lastname: Longuet
authors.forename: J L
authors.initials: JL
authors.lastname: Vildé
mesh_terms: D002648:Child; D006801:Humans; D010612:Pharyngitis / Q000150:complications; D012213:Rheumatic Fever / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology*; D013290:Streptococcal Infections / Q000150:complications
vernacular_title: Rhumatisme articulaire aigu: physiopathologie, aspects cliniques.