title: Primary cutaneous plasmacytoma: the use of in situ hybridization to detect monoclonal immunoglobulin light-chain mRNA.
abstract: A case of primary cutaneous plasmacytoma in a 16-year-old male is described. The neoplastic nature of the plasma cell infiltrate has been clearly established by the demonstration of monoclonal kappa immunoglobulin light-chain mRNA using in situ hybridization with biotin-labelled oligonucleotide probes applied to routine tissue sections.
authors.affiliation: Department of Pathology, Royal Infirmary, Glasgow, Scotland, UK.
authors.forename: E
authors.initials: E
authors.lastname: Walker
authors.forename: A G
authors.initials: AG
authors.lastname: Robertson
authors.forename: J G
authors.initials: JG
authors.lastname: Boorman
authors.forename: A M
authors.initials: AM
authors.lastname: McNicol
mesh_terms: D000293:Adolescent; D006801:Humans; D007147:Immunoglobulin Light Chains / Q000235:genetics*; D008297:Male; D009693:Nucleic Acid Hybridization; D010954:Plasmacytoma / Q000235:genetics* / Q000276:immunology; D012333:RNA, Messenger / Q000032:analysis; D012334:RNA, Neoplasm / Q000032:analysis*; D012878:Skin Neoplasms / Q000235:genetics* / Q000276:immunology
chemical_list: D007147:Immunoglobulin Light Chains; D012333:RNA, Messenger; D012334:RNA, Neoplasm