title: The influence of a solid and liquid bolus on food-stimulated gastroesophageal reflux.
abstract: Using a radiological method to demonstrate food-stimulated gastroesophageal reflux (GER), a comparative study was carried out employing a solid, already validated bolus versus a liquid one. One hundred and four consecutive patients received both a solid and a liquid bolus in randomized order. GER was observed in 37 (35.6%) patients receiving the solid bolus versus 28 (26.9%) with the liquid one. This means that the solid bolus provokes significantly more reflux (P less than 0.02). GER, grade II (reflux above the level of the carina), occurred equally often as a result of both types of bolus, however. The study suggests that significant, food-stimulated GER is independent of the consistency of the foodstuffs and may be detected employing a liquid bolus. This result might be used in the examination of infants for GER, using milk as a food stimulus.
authors.affiliation: GI Motility Laboratory, Aarhus Kommunehospital, University of Aarhus, Denmark.
authors.forename: A
authors.initials: A
authors.lastname: Naeser
authors.forename: J K
authors.initials: JK
authors.lastname: Behrens
authors.forename: L
authors.initials: L
authors.lastname: Vejen-Christiansen
authors.forename: P
authors.initials: P
authors.lastname: Funch-Jensen
authors.forename: P
authors.initials: P
authors.lastname: Thommesen
mesh_terms: D000328:Adult; D000368:Aged; D004326:Drinking; D004435:Eating; D005260:Female; D005502:Food; D005764:Gastroesophageal Reflux / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies