Roles of the vinyl chloride oxidation products 1-chlorooxirane and 2-chloroacetaldehyde in the in vitro formation of etheno adducts of nucleic acid bases [corrected].
Guengerich
F P
FP
Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146.
D000079:Acetaldehyde / Q000031:analogs & derivatives* / Q000737:chemistry; D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D004247:DNA / Q000737:chemistry*; D005027:Ethylene Oxide / Q000031:analogs & derivatives* / Q000737:chemistry; D006736:Horses; D066298:In Vitro Techniques; D007700:Kinetics; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology; D010084:Oxidation-Reduction; D051381:Rats; D011919:Rats, Inbred Strains; D014752:Vinyl Chloride / Q000737:chemistry*
C015061:chloroethylene oxide; D004247:DNA; D003577:Cytochrome P-450 Enzyme System; C004656:chloroacetaldehyde; D000079:Acetaldehyde; D005027:Ethylene Oxide; D014752:Vinyl Chloride