Digitalis toxicity. Using immunotherapy when supportive care isn't enough.
Significant digitalis toxicity, although uncommon, is a medical emergency. Recognition of the problem and good supportive care (eg, administration of activated charcoal and binding resins, correction of potassium levels, restoration of heart rhythm) are the cornerstones of treatment. If indicated, immunotherapy with digoxin immune Fab (Digibind) is a valuable and effective tool.
Krisanda
T J
TJ
Department of Emergency Medicine, York Hospital, PA 17405.
D001145:Arrhythmias, Cardiac / Q000139:chemically induced / Q000188:drug therapy; D002606:Charcoal / Q000627:therapeutic use; D004071:Digitalis Glycosides / Q000506:poisoning*; D004077:Digoxin / Q000276:immunology / Q000506:poisoning; D004630:Emergencies; D006801:Humans; D007008:Hypokalemia / Q000139:chemically induced / Q000188:drug therapy; D007140:Immunoglobulin Fab Fragments / Q000627:therapeutic use; D011041:Poisoning / Q000175:diagnosis / Q000628:therapy
D004071:Digitalis Glycosides; D007140:Immunoglobulin Fab Fragments; C050199:digoxin antibodies Fab fragments; D002606:Charcoal; D004077:Digoxin