Ultrastructural study of Helicobacter pylori adherence properties in gnotobiotic piglets.
Ultrastructural examination of gastric mucosa from Helicobacter pylori-infected gnotobiotic piglets identified four general adherence patterns comparable to those observed in human patients. Intimate associations between the bacterial and mucosal cell membranes, including cuplike invaginations and adherence pedestals, were present and were accompanied by alterations to microvilli and cell membrane morphology.
Rudmann
D G
DG
Department of Veterinary Pathobiology, School of Veterinary Medicine, Ohio State University, Columbus 43210.
Eaton
K A
KA
Krakowka
S
S
D000818:Animals; D001422:Bacterial Adhesion; D005753:Gastric Mucosa / Q000382:microbiology*; D005756:Gastritis / Q000209:etiology; D005856:Germ-Free Life; D016480:Helicobacter pylori / Q000502:physiology / Q000648:ultrastructure*; D006801:Humans; D013552:Swine / Q000382:microbiology*