Scleroderma-like skin indurations in a child with phenylketonuria: a clinicopathologic correlation and review of the literature.
Scleroderma-like skin lesions are one sequela of phenylketonuria. We describe a child with phenylketonuria and associated dermal connective tissue changes consistent with early inflammatory scleroderma. The severity of the skin lesions apparently waned with dietary restriction of phenylalanine.
Nova
M P
MP
Pacific Dermatopathology Laboratories, San Diego, CA 92110.
Kaufman
M
M
Halperin
A
A
D001706:Biopsy; D005260:Female; D006801:Humans; D007223:Infant; D010661:Phenylketonurias / Q000150:complications*; D012594:Scleroderma, Localized / Q000209:etiology* / Q000473:pathology