[Complete and homogenous trisomy 9 detected in utero].
During a gestation with oligoamnios and growth retardation noticed at 25th week an amniocentesis allowed us to discover the 14th case of complete trisomy 9, the third detected in utero. It is also the first without heart malformation, otherwise phenotype was usual. The liver had small areas of necrosis with calcifications and slight fibrosis which may be in relation with two cordocentesis made before expulsion. The important phenotype alterations and poor outcome of fetuses with trisomy 9 justify elective abortion.
Raffi
F
F
Service de Gynécologie, CHG Tulle.
Geneix
A
A
Satge
D
D
Fallouh
B
B
Brunerie
A M
AM
Lemery
D
D
Malet
P
P
D000032:Abortion, Therapeutic; D000328:Adult; D000649:Amniocentesis / Q000379:methods*; D002899:Chromosomes, Human, Pair 9; D005260:Female; D005317:Fetal Growth Retardation / Q000150:complications / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D008107:Liver Diseases / Q000150:complications / Q000151:congenital / Q000473:pathology; D008297:Male; D016104:Oligohydramnios / Q000175:diagnosis* / Q000209:etiology; D010641:Phenotype; D011296:Prenatal Diagnosis / Q000379:methods*; D014314:Trisomy
Trisomie 9 totale et homogène dépistée in utero.