title: Isotopic differences in the lithium transport rate in human erythrocytes during simultaneous incubations with the stable isotopes 6Li and 7Li.
abstract: The membrane transport of the two stable lithium isotopes, 6Li and 7Li, by erythrocytes has been studied using a dual channel atomic absorption spectroscopic technique. 6Li appears to be taken up preferentially to 7Li, in the ratio of 10 to 40%, depending on the concentration of total lithium and on the lithium isotopic ratio in the external medium.
authors.affiliation: Biomedical Research Laboratory, School of Health Sciences, Wolverhampton Polytechnic, U.K.
authors.forename: M S
authors.initials: MS
authors.lastname: Hughes
authors.forename: N J
authors.initials: NJ
authors.lastname: Birch
mesh_terms: D001692:Biological Transport; D004305:Dose-Response Relationship, Drug; D004355:Drug Stability; D004910:Erythrocyte Membrane / Q000378:metabolism*; D006801:Humans; D007554:Isotopes; D008094:Lithium / Q000493:pharmacokinetics*; D013054:Spectrophotometry, Atomic / Q000379:methods
chemical_list: D007554:Isotopes; D008094:Lithium