Assembly-disassembly of the nuclear lamina.
Recently, progress in the study of lamins has been made in three areas: signals required for targetting newly synthesized lamins to the correct subnuclear compartment have been identified; information on lamina assembly has been obtained from in vitro studies using bacterially expressed proteins; and a mechanistic explanation for how the nuclear lamina is diassembled at the onset of mitosis is emerging.
Nigg
E A
EA
Swiss Institute for Experimental Cancer Research, Epalinges.
D000818:Animals; D002453:Cell Cycle / Q000502:physiology; D002843:Chromatin / Q000502:physiology; D034882:Lamins; D008938:Mitosis / Q000502:physiology; D015530:Nuclear Matrix / Q000502:physiology*; D009687:Nuclear Proteins / Q000502:physiology*; D010766:Phosphorylation
D002843:Chromatin; D034882:Lamins; D009687:Nuclear Proteins