title: [Treatment of large skin defect with 6:1 meshed skin autograft and 1.5:1 meshed fresh porcine skin overlay].
abstract: The use of expanded mesh skin graft from limited donor sites has greatly increased wound coverage. However, grafts with an expansion size of 6:1 or greater often heal slowly or are lost because of local infection. Three patients with large skin defects in lower extremity have been treated with 6:1 mesh autograft overlayed by 1.5:1 fresh porcine skin mesh graft. Epithelium grown from both grafts could be found. The autografts continuously expanded under the xenografts. The outer xenografts gradually separated and desquamated, on an average, in 14 days. This technique enables resurfacing of a large area of skin defect from smaller donor sites.
authors.affiliation: Department of Surgery, Kaohsiung Medical College Hospital, Taiwan, Republic of China.
authors.forename: C K
authors.initials: CK
authors.lastname: Chou
authors.forename: S D
authors.initials: SD
authors.lastname: Lin
authors.forename: C C
authors.initials: CC
authors.lastname: Yang
authors.forename: C S
authors.initials: CS
authors.lastname: Lai
mesh_terms: D000368:Aged; D000818:Animals; D006801:Humans; D008297:Male; D008875:Middle Aged; D016038:Skin Transplantation / Q000379:methods*; D013552:Swine; D014183:Transplantation, Heterologous