title: High-dose cimetidine for the treatment of metastatic renal cell carcinoma. A Hoosier Oncology Group study.
abstract: The Hoosier Oncology Group evaluated cimetidine in 42 patients with metastatic renal cell carcinoma. There were two complete remissions that lasted for 26 and 33+ months in 38 evaluable patients. There were no partial remissions. Toxicity was minimal. Patients with renal cell carcinoma can occasionally respond to cimetidine with long-term remission.
authors.affiliation: Oncology & Hematology Associates, Roanoke, Virginia.
authors.forename: L
authors.initials: L
authors.lastname: Inhorn
authors.forename: S D
authors.initials: SD
authors.lastname: Williams
authors.forename: S
authors.initials: S
authors.lastname: Nattam
authors.forename: D
authors.initials: D
authors.lastname: Stephens
mesh_terms: D002292:Carcinoma, Renal Cell / Q000188:drug therapy* / Q000556:secondary; D002927:Cimetidine / Q000008:administration & dosage / Q000627:therapeutic use*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D008875:Middle Aged
chemical_list: D002927:Cimetidine