Post-viral immunodeficiencies in man.
Secondary immunodeficiencies (as defined) of T-cells, B-cells, and phagocytes can be caused by viral infections, and have already been demonstrated for over 20 viruses affecting man. The severity and duration can vary with genetic constitution and age at infection, and post-viral atopy or deregulation permitting triggering of autoimmune diseases are now well-recognised. Various mechanisms are briefly discussed together with some potential treatments, and there is still much to be studied and learned.
Hobbs
J R
JR
Department of Immunology, Charing Cross and Westminster Medical School, London.
D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D001402:B-Lymphocytes / Q000276:immunology; D006801:Humans; D007116:Immunization, Passive; D007153:Immunologic Deficiency Syndromes / Q000209:etiology* / Q000628:therapy; D010586:Phagocytes / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology; D014777:Virus Diseases / Q000150:complications / Q000276:immunology* / Q000628:therapy
D000276:Adjuvants, Immunologic; D000998:Antiviral Agents