title: [Trisomy 18 (Edwards syndrome): two case reports].
abstract: Edwards (or trisomy 18) syndrome, with a frequency of about 1 over 8000 births, is commonly characterized by a very short survival; those rare cases reported with ages of 12 months or more, always were demonstrated to be chromosomic mosaicisms. Two affected children with completely different outcomes are here described; the first with a classic short-life evolution, in opposition to the second with long survival, the last a good example of all those various biological, psychological and social support interventions in these circumstances, very rare to match with, for this appears to be a trisomy 18 without mosaicism.
authors.affiliation: Divisione di Patologia Neonatale, Ospedale Maggiore di Lodi Mi, Italia.
authors.forename: P
authors.initials: P
authors.lastname: Morosini
authors.forename: C
authors.initials: C
authors.lastname: Verdura
authors.forename: F
authors.initials: F
authors.lastname: Paolillo
authors.forename: M
authors.initials: M
authors.lastname: Fornari
authors.forename: M L
authors.initials: ML
authors.lastname: Argentiero
authors.forename: C
authors.initials: C
authors.lastname: Belloni
mesh_terms: D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D002887:Chromosomes, Human, Pair 18; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D014314:Trisomy
vernacular_title: La trisomia 18 (sindrome di Edwards): considerazioni su due casi.