Influence of disc degeneration on mechanism of thoracolumbar burst fractures.
In order to clarify the pathomechanism of thoracolumbar burst fractures and to evaluate the influence of disc degeneration and bone mineral density, a biomechanical study was performed using cadaveric spines. Eleven motion segments of thoracolumbar spines from human cadavers were compressed vertically until a fracture occurred. In addition, bone mineral density and degree of disc degeneration were determined for each specimen. Compression of 7 of 11 specimens resulted in the typical burst fracture characterized by retropulsion of a bony fragment into the spinal canal and an increase of the interpedicular distance. All seven specimens showed disruptions of the middle end plate and disc materials in the vertebral body. The fracture line was located between the middle of the end plate and the middle of the posterior wall cortex. No burst fractures were seen in the specimens with severely degenerated discs and osteoporosis. In order to confirm the stress state in a vertebra that induces the burst fracture, finite element analysis of one motion segment was also carried out under the same mechanical conditions as the experiments in this study. As a result of calculation for the healthy disc, the highest stresses under axial compression were concentrated in the following areas: the middle of the end plate, the cancellous bone under the nucleus pulposus, and the middle of the posterior wall cortex. This implies that the above regions are more vulnerable to vertical compressive load. In the analysis of specimens with severely degenerated discs, stresses were very low at the end plate and cancellous bone under the nucleus.(ABSTRACT TRUNCATED AT 250 WORDS)
Shirado
O
O
Department of Orthopaedic Surgery, Hokkaido University School of Medicine, Japan.
Kaneda
K
K
Tadano
S
S
Ishikawa
H
H
McAfee
P C
PC
Warden
K E
KE
D015519:Bone Density; D002102:Cadaver; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000503:physiopathology*; D008159:Lumbar Vertebrae / Q000293:injuries*; D008875:Middle Aged; D010024:Osteoporosis / Q000503:physiopathology; D016103:Spinal Fractures / Q000503:physiopathology*; D013314:Stress, Mechanical; D013904:Thoracic Vertebrae / Q000293:injuries*