Pathogenesis of vertebral crush fractures in men.
In a series of 70 men with vertebral crush fractures, 38 (54%) were found to have an underlying secondary cause of osteoporosis such as hypogonadism (16%), oral steroid therapy (13%), neoplastic disease (9%), excess alcohol consumption (6%), gastric surgery (1%) or a combination of these factors (10%). The diagnosis of secondary osteoporosis was not always apparent from the clinical history and physical examination, suggesting that appropriate investigations should be performed in all men with vertebral crush fractures.
Baillie
S P
SP
Department of Medicine (Geriatrics), University of Newcastle upon Tyne, Newcastle General Hospital.
Davison
C E
CE
Johnson
F J
FJ
Francis
R M
RM
D000368:Aged; D000369:Aged, 80 and over; D000428:Alcohol Drinking / Q000009:adverse effects; D005598:Fractures, Spontaneous / Q000209:etiology*; D005743:Gastrectomy; D006801:Humans; D007006:Hypogonadism / Q000150:complications; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D009369:Neoplasms / Q000150:complications; D010024:Osteoporosis / Q000150:complications* / Q000209:etiology; D011183:Postoperative Complications / Q000209:etiology; D012307:Risk Factors; D016103:Spinal Fractures / Q000209:etiology*; D013256:Steroids / Q000009:adverse effects; D013739:Testosterone / Q000097:blood
D013256:Steroids; D013739:Testosterone; D007986:Luteinizing Hormone