title: [Peranal ulcers caused by ergotamine-containing suppositories].
abstract: Perianal ulcerations caused by suppositories application is an exceptional situation. We describe a 64 years old female with recurrent painless perianal ulcerations evoluting from 14 months. She medicates herself daily, since 8 to 10 years, with ergotamine tartarate suppositories, for the treatment of migraine. The diagnosis of ulcerated cutaneous drug reaction induced by ergotamine tartarate was confirmed by the complete healing of the lesions after stopping this medication and by their recurrence after the reintroduction of the treatment. These ulcerations are probably due to vasospasm of regional arterioles.
authors.affiliation: Serviço de Dermatologia, Hospitais da Universidade de Coimbra.
authors.forename: A P
authors.initials: AP
authors.lastname: Baptista
authors.forename: A
authors.initials: A
authors.lastname: Mariano
authors.forename: A
authors.initials: A
authors.lastname: Machado
mesh_terms: D001004:Anus Diseases / Q000139:chemically induced*; D004878:Ergotamine / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D013488:Suppositories; D014456:Ulcer / Q000139:chemically induced
chemical_list: D013488:Suppositories; D004878:Ergotamine
vernacular_title: Ulcerações perianais por supositórios contendo ergotamina.