title: Fatal co-infection with pulmonary tuberculosis and herpes simplex virus 1 pneumonia under steroid treatment.
abstract: We report a case of adult respiratory distress syndrome in a 65 yr old man under inappropriate steroid therapy who developed both Herpes simplex virus 1 (HSV) and Mycobacterium tuberculosis pneumonia; we conclude from clinical and histological data that HSV 1 played a major role in the fatal outcome of this immunocompromised patient, in spite of acyclovir treatment.
authors.affiliation: Service de Réanimation Médicale et Maladies Infectieuses, Hôpital Pontchaillou, Universite de Rennes, France.
authors.forename: C
authors.initials: C
authors.lastname: Charasse
authors.forename: J M
authors.initials: JM
authors.lastname: Liégaux
authors.forename: Y
authors.initials: Y
authors.lastname: Le Tulzo
authors.forename: C
authors.initials: C
authors.lastname: Camus
authors.forename: R
authors.initials: R
authors.lastname: Thomas
authors.forename: F
authors.initials: F
authors.lastname: Cartier
authors.forename: M P
authors.initials: MP
authors.lastname: Ramée
authors.forename: P
authors.initials: P
authors.lastname: André
mesh_terms: D000368:Aged; D006561:Herpes Simplex / Q000150:complications* / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000009:adverse effects*; D011024:Pneumonia, Viral / Q000150:complications* / Q000209:etiology / Q000382:microbiology; D012128:Respiratory Distress Syndrome / Q000175:diagnosis / Q000209:etiology*; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000175:diagnosis / Q000209:etiology
chemical_list: D008775:Methylprednisolone