title: [Diagnostic value of C-reactive protein and D-dimer in deep venous thrombosis].
abstract: The accuracy of C-reactive protein (CRP) and D-dimer in detecting deep venous thrombosis was compared with phlebography in a consecutive series of 69 patients admitted to hospital due to suspicion of thrombosis in the leg. With a sensitivity of 100%, C-reactive protein can exclude the possibility of thrombosis. The sensitivity of D-dimer was too low to exclude the diagnosis. With a high discrimination limit the specificity of D-dimer was 100%, which may confirm the diagnosis. Ideally, screening with C-reactive protein and D-dimer could reduce the need of venography by 38%.
authors.affiliation: Medisinsk avdeling, Aust-Agder Sentralsjukehus, Arendal.
authors.forename: B
authors.initials: B
authors.lastname: Jøssang
authors.forename: I
authors.initials: I
authors.lastname: Runde
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002097:C-Reactive Protein / Q000032:analysis*; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D013924:Thrombophlebitis / Q000097:blood* / Q000175:diagnosis / Q000000981:diagnostic imaging
chemical_list: D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D; D002097:C-Reactive Protein
vernacular_title: Diagnostisk verdi av C-reaktivt protein og D-dimer ved dyp venetrombose.