title: [Implantation metastasis of adenocarcinoma of the paranasal sinuses in the middle ear].
abstract: Carcinoma of the middle ear is a rare disease. We report about a 65-year-old man in which case it is assumed that a transtubal implantation metastasis of an adenocarcinoma had settled in the middle ear. Regular irrigation of the operated nose and unnoticed carcinoma recurrence were main assumptions for intracanicular metastasis. With experiments on dead and alive we could show that irrigation fluid intrudes through the tube into the middle ear. Finally the problem of growth of carcinoma cells on intact epithelial surfaces is critically discussed.
authors.affiliation: Universitäts-HNO-Klinik Münster.
authors.forename: J
authors.initials: J
authors.lastname: Abrams
authors.forename: K B
authors.initials: KB
authors.lastname: Hüttenbrink
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000556:secondary*; D000368:Aged; D004428:Ear Neoplasms / Q000473:pathology / Q000556:secondary*; D004432:Ear, Middle / Q000473:pathology*; D006801:Humans; D008297:Male; D008416:Mastoid / Q000473:pathology; D008444:Maxillary Sinus Neoplasms / Q000473:pathology*; D009366:Neoplasm Seeding; D007507:Therapeutic Irrigation / Q000295:instrumentation*; D014057:Tomography, X-Ray Computed
vernacular_title: Die Implantationsmetastase eines Adenokarzinoms der Nebenhöhlen im Mittelohr.