Fatal acute babesiosis in a juvenile wild dog (Lycaon pictus).
Clinical examination of a 75-day-old captive juvenile wild dog suffering from lassitude revealed pale mucous membranes, icterus, laboured respiration, a "water-hammer" pulse and splenomegaly. A peripheral blood smear containing numerous Babesia-infected erythrocytes confirmed the diagnosis of babesiosis. Treatment was unsuccessful and the animal died shortly after receiving a blood transfusion. The findings at necropsy were typical for acute babesiosis and included anaemia, icterus, splenomegaly and haemoglobinuria. In addition, marked atrophy of the thymus and lymph nodes was evident. Microscopic and electron microscopic examination of selected tissues disclosed high parasitaemia with vascular stasis and injury to both endothelial and parenchymal components. It is speculated that vaccination-induced immune incompetence predisposed to development of clinical babesiosis.
Colly
L P
LP
Johannesburg Zoological Gardens, Parkview, Republic of South Africa.
Nesbit
J W
JW
D000818:Animals; D000835:Animals, Wild; D001404:Babesiosis / Q000473:pathology*; D002335:Carnivora / Q000469:parasitology*; D004912:Erythrocytes / Q000469:parasitology; D008168:Lung / Q000473:pathology; D008854:Microscopy, Electron; D009206:Myocardium / Q000473:pathology