title: A new bind for Myc.
abstract: Recent studies centered on the c-Myc basic/helix-loop-helix/leucine zipper (B/HLH/LZ) motifs have led to the identification of a DNA recognition sequence for c-Myc and the isolation of a novel protein that forms a DNA-binding complex with c-Myc in vitro. These advances may make it possible to address directly the long-standing question of c-Myc function in vivo.
authors.affiliation: Department of Cancer Research, Merck Sharp and Dohme Research Laboratories, West Point, PA 19486.
authors.forename: G C
authors.initials: GC
authors.lastname: Prendergast
authors.forename: E B
authors.initials: EB
authors.lastname: Ziff
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D001665:Binding Sites; D003001:Cloning, Molecular; D004247:DNA / Q000378:metabolism; D016259:Genes, myc; D008969:Molecular Sequence Data; D016271:Proto-Oncogene Proteins c-myc / Q000235:genetics / Q000378:metabolism*
chemical_list: D016271:Proto-Oncogene Proteins c-myc; D004247:DNA