title: Quantification of motor deficit in Parkinson's disease with a motor performance test series.
abstract: It was the purpose of the present study to quantify the expected motor deficit in parkinsonian patients with the computer assisted Motor Performance Test Series (MPS), version 05.87 by Schuhfried (1987) and to examine which of the motor test variables found correlate at a significance level of p less than 0.01 with items of "motor examination" recorded at neurological examination and "activities of daily living" of the Unified Parkinson's Disease Rating Scale (UPDRS), version 3.0. 38 patients with idiopathic Parkinson's disease (PD) stages I-IV according to Hoehn and Yahr, aged 41 to 73 years were studied. The study design, i.e. initial rating by the physician followed immediately by testing of motor function with MPS was strictly adhered to in each patient. Physician's rating of rigor and the scores of the semiquantitative tests (finger taps, hand movements and alternating movements) as expression of hypokinesia and the "activities of daily living" correlated with the 3 factors of the Motor Performance Test Series at a highly significant level independent of disease stage. Tremor is only partly and never significantly reflected in the motor data measured. Stages I-II and II-IV (Hoehn and Yahr) differ significantly in the representative data of the Motor Performance Test Series. The results of the study support the assumption that MPS is a valid instrument for quantitative measurement of the motor deficit in parkinsonian patients, but that only some subtests are "pathognomonic".
authors.affiliation: Neurological Hospital Rosenhügel, Vienna, Austria.
authors.forename: M M
authors.initials: MM
authors.lastname: Pinter
authors.forename: R J
authors.initials: RJ
authors.lastname: Helscher
authors.forename: C O
authors.initials: CO
authors.lastname: Nasel
authors.forename: E
authors.initials: E
authors.lastname: Riedl
authors.forename: G
authors.initials: G
authors.lastname: Schnaberth
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009127:Muscle Rigidity / Q000503:physiopathology; D010300:Parkinson Disease / Q000503:physiopathology*; D011597:Psychomotor Performance; D012720:Severity of Illness Index; D014202:Tremor / Q000503:physiopathology