Three cases of alpha 1-antitrypsin deficiency: a review of diagnostic and therapeutic strategies.
Deficiency of alpha 1-antitrypsin is an unusual cause of emphysema. This deficiency may be suspected when the age of onset and severity of disease are out of proportion to the history of inhaled agents (usually cigarette exposure). Three patients seen during a relatively short time in a private practice underscore the variability of presentation. Proper diagnosis offers such patients several benefits, particularly in view of new potential therapies.
Jenkins
D W
DW
Skinner Clinic, San Antonio, Tex.
D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000175:diagnosis* / Q000235:genetics; D008176:Lung Volume Measurements; D008297:Male; D010641:Phenotype; D000515:alpha 1-Antitrypsin / Q000235:genetics; D019896:alpha 1-Antitrypsin Deficiency
D000515:alpha 1-Antitrypsin