title: Plasma zinc uptake from a supplement during submaximal running.
abstract: The uptake of zinc (Zn) into the plasma after the ingestion of 25 mg of Zn from multivitamin-mineral supplement was studied in 10 men during running (R) and control (C) conditions; the R was for 2 h at 60-65% of their maximal oxygen uptake. Subjects took the supplement with 200 ml of deionized water before the R or C (0-time). Blood was drawn before the Zn load and every 30 min for 3 h. By 2 h, plasma Zn concentrations had risen to values that were 151 +/- 7% and 149 +/- 5% of (0-time) R and C concentrations, respectively. Furthermore, the average rates of Zn uptake into the plasma did not differ between the R and C (4.4 vs 3.8 mumol.l-1.h-1) conditions. Finally, areas under the curve were not different (R: 13.2 +/- 1.8 mumol.l-1.3h-1; C: 11.5 +/- 1.5 mumol.l-1.3h-1). In summary, submaximal endurance running did not affect plasma Zn uptake and therefore absorption of Zn from a supplement taken just prior to exercise. The effect of chronic exercise on Zn absorption remains to be determined.
authors.affiliation: Department of Military Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814-4799.
authors.forename: A
authors.initials: A
authors.lastname: Singh
authors.forename: F M
authors.initials: FM
authors.lastname: Moses
authors.forename: B L
authors.initials: BL
authors.lastname: Smoak
authors.forename: P A
authors.initials: PA
authors.lastname: Deuster
mesh_terms: D000042:Absorption; D000328:Adult; D006801:Humans; D008297:Male; D009753:Nutritive Value; D010953:Plasma Volume; D012420:Running; D013997:Time Factors; D015032:Zinc / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*
chemical_list: D015032:Zinc