title: The effect of Healon and timolol on early postoperative intraocular pressure after extracapsular cataract extraction with implantation of a posterior chamber lens.
abstract: In a prospective, randomized, masked study the effect of sodium hyaluronate (Healon) and timolol on the acute intraocular pressure rise after extracapsular cataract extraction with implantation of a posterior chamber lens were evaluated. Intraocular pressure was measured preoperatively and 3-6 h and 24 h postoperatively. When no timolol was used, a significant rise in intraocular pressure was observed at 3-6 h, whether or not Healon was aspirated. Timolol reduced the intraocular pressure rise, especially during the first 3-6 h after surgery. When timolol was not applied at the end of surgery, IOP exceeded 30 mmHg in 28% 3-6 h postoperatively, compared to only 4% when timolol was applied.
authors.affiliation: Department of Ophthalmology, Lillehammer Fylkessykehus, Norway.
authors.forename: N
authors.initials: N
authors.lastname: Anmarkrud
authors.forename: B
authors.initials: B
authors.lastname: Bergaust
authors.forename: T
authors.initials: T
authors.lastname: Bulie
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D002387:Cataract Extraction; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000494:pharmacology*; D007429:Intraocular Pressure / Q000187:drug effects*; D007910:Lenses, Intraocular; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000503:physiopathology*; D011183:Postoperative Complications / Q000503:physiopathology*; D011446:Prospective Studies; D013999:Timolol / Q000494:pharmacology*; D014065:Tonometry, Ocular
chemical_list: D013999:Timolol; D006820:Hyaluronic Acid