title: A modular numerical model of the cardiovascular system for studying and training in the field of cardiovascular physiopathology.
abstract: A modular numerical model of the cardiovascular system has been developed to reproduce the most important circulatory phenomena in terms of pressure and volume relationships. It is an easy tool to use, designed to be used with a friendly approach on any IBM or compatible personal computer: it offers a wide selection of graphical and numerical outputs and can be rearranged easily for a particular experiment. A set of subroutines related to different circulatory phenomena has been developed; they can be assembled easily together and communicate with each other by two variables. A full description of the existing subroutines is presented in this paper with three different application examples resulting from the rearrangement of the existing software modules: the first concerns the behaviour of the natural ventricle model itself and can be regarded as a ventricle stand-alone characterization test in terms of preload and afterload sensitivities, the second is related to the use of a pneumatic ventricle instead of the model of the natural ventricle, and the third is a full model of the cardiocirculatory system.
authors.affiliation: Istituto di Tecnologie Biomediche CNR, Rome, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Ferrari
authors.forename: C
authors.initials: C
authors.lastname: De Lazzari
authors.forename: R
authors.initials: R
authors.lastname: Mimmo
authors.forename: G
authors.initials: G
authors.lastname: Tosti
authors.forename: D
authors.initials: D
authors.lastname: Ambrosi
mesh_terms: D002309:Cardiology / Q000193:education*; D002318:Cardiovascular Diseases / Q000503:physiopathology* / Q000628:therapy; D003198:Computer Simulation; D006353:Heart-Assist Devices; D006439:Hemodynamics; D006801:Humans; D008955:Models, Cardiovascular; D012985:Software Design