[The effectiveness of preventive use of antibiotics in Cesarean section with a single dose: comparison of cefotaxime with amoxicillin plus clavulanic acid].
The effectiveness of a single prophylactic dose of two broad spectrum antibiotics, during Caesarean section, was compared and evaluated. In 119 consecutive cases at the Cantonal Hospital in Winterthur, Switzerland, either 1 g i.v. cefotaxime or 1,2 g amoxicillin plus clavulanic acid were administered after clamping the umbilical cord during Caesarean section. The study shows that single dose prophylaxis of either regimen provides adequate cover in preventing morbidity in Caesarean section, in both high-risk and low-risk groups.
Köppel
R
R
Frauenklinik, Kantonsspital Winterthur, Schweiz.
Kaehler
D
D
Benz
J
J
D000328:Adult; D000658:Amoxicillin / Q000008:administration & dosage*; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002439:Cefotaxime / Q000008:administration & dosage*; D002585:Cesarean Section; D019818:Clavulanic Acid; D002969:Clavulanic Acids / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011292:Premedication; D011446:Prospective Studies; D011645:Puerperal Infection / Q000517:prevention & control*; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000517:prevention & control*
D000900:Anti-Bacterial Agents; D002969:Clavulanic Acids; D019818:Clavulanic Acid; D000658:Amoxicillin; D002439:Cefotaxime
Die Wirksamkeit der Antibiotika-Prophylaxe bei Kaiserschnitt durch Einzeldosis: Vergleich Cefotaxim gegen Amoxicillin plus Clavulansäure.