title: Relationship between chronic ovine dermatophilosis and levels of T6 lymphocyte antigen staining in peripheral blood mononuclear cells.
abstract: Quantification of a T6-lymphocyte antigen in peripheral blood mononuclear cells of sheep was used to select 15 from 48 one year old Merino ewes not previously exposed to Dermatophilus congolensis infection. These sheep were compared in response to challenge with D. congolensis zoospores and levels of T-6 lymphocyte antigen in peripheral blood mononuclear cells with 15 Merino ewes of similar age and strain from a different site that had been treated and recovered from chronic dermatophilosis. The T-6 lymphocyte antigen levels were significantly lower in the chronic dermatophilosis sheep and they developed significantly more severe lesions than the selected, previously unexposed sheep despite the former sheep having high serum antibody levels to D. congolensis. Measurement of the fleece characteristics, wax and suint concentration showed no differences between the groups that might have explained the considerable differences in their susceptibility to dermatophilosis.
authors.affiliation: Animal Health Division, Department of Agriculture, South Perth, Australia.
authors.forename: T M
authors.initials: TM
authors.lastname: Ellis
authors.forename: S S
authors.initials: SS
authors.lastname: Sutherland
authors.forename: R
authors.initials: R
authors.lastname: Turnor
authors.forename: R
authors.initials: R
authors.lastname: Krueger
mesh_terms: D000192:Actinomycetales / Q000276:immunology; D000193:Actinomycetales Infections / Q000276:immunology / Q000662:veterinary*; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D002908:Chronic Disease; D005260:Female; D007963:Leukocytes, Mononuclear / Q000276:immunology*; D012756:Sheep; D012757:Sheep Diseases / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*; D014935:Wool / Q000737:chemistry
chemical_list: D000907:Antibodies, Bacterial