title: Untreated neuroborreliosis: Bannwarth's syndrome evolving into acute schizophrenia-like psychosis. A case report.
abstract: In general, meningopolyradiculitis (Bannwarth's syndrome, stage 2 of neuroborreliosis) follows a predictable monophasic self-limiting course. In contrast, we report the case of a patient with an untreated meningopolyradiculitis which evolved into acute schizophrenia-like psychosis due to persistent infection with Borrelia burgdorferi. The psychosis resolved within 1 week of treatment with ceftriaxone. This case shows that the usually benign monophasic meningopolyradiculitis may progress to severe CNS complications, which may have implications on current pathophysiological beliefs.
authors.affiliation: Neurologische Klinik, Universität, Heidelberg, Federal Republic of Germany.
authors.forename: U
authors.initials: U
authors.lastname: Roelcke
authors.forename: W
authors.initials: W
authors.lastname: Barnett
authors.forename: E
authors.initials: E
authors.lastname: Wilder-Smith
authors.forename: D
authors.initials: D
authors.lastname: Sigmund
authors.forename: W
authors.initials: W
authors.lastname: Hacke
mesh_terms: D000208:Acute Disease; D000907:Antibodies, Bacterial / Q000134:cerebrospinal fluid; D015748:Borrelia burgdorferi Group / Q000276:immunology / Q000302:isolation & purification*; D002443:Ceftriaxone / Q000627:therapeutic use; D002908:Chronic Disease; D003937:Diagnosis, Differential; D004660:Encephalitis / Q000134:cerebrospinal fluid / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid; D008193:Lyme Disease / Q000134:cerebrospinal fluid / Q000150:complications* / Q000188:drug therapy / Q000523:psychology; D008297:Male; D008581:Meningitis / Q000134:cerebrospinal fluid / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000209:etiology*; D011128:Polyradiculopathy / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D012559:Schizophrenia / Q000175:diagnosis; D013577:Syndrome
chemical_list: D000907:Antibodies, Bacterial; D007074:Immunoglobulin G; D002443:Ceftriaxone