title: [A review of clinical studies on the efficacy and tolerance of intravenous ciprofloxacin].
abstract: A review of the literature. Ciprofloxacin is a fluorinate quinolone with a broad spectrum of activity against gram-positive and gram-negative organisms. Orally administered ciprofloxacin has been successfully used in a variety of clinical settings, but reservations remain regarding the use of oral antibiotics in the treatment of serious infections. Furthermore, many seriously ill patients are unable to take drugs orally. An intravenous form of ciprofloxacin has undergone extensive clinical investigation for the treatment of a variety of infections in hospitalized patients. Reported here are the results of some clinical trials showing the effectiveness and safety of intravenous/sequential therapy with ciprofloxacin.
authors.affiliation: Divisione di medicina II, Ospedale San Raffaele, Milano.
authors.forename: M
authors.initials: M
authors.lastname: Memoli
mesh_terms: D002939:Ciprofloxacin / Q000008:administration & dosage* / Q000009:adverse effects; D002986:Clinical Trials as Topic; D004361:Drug Tolerance; D006801:Humans; D007275:Injections, Intravenous; D012141:Respiratory Tract Infections / Q000188:drug therapy; D014552:Urinary Tract Infections / Q000188:drug therapy
chemical_list: D002939:Ciprofloxacin
vernacular_title: Rassegna di studi clinici sull'efficacia e tollerabilità della ciprofloxacina endovenosa.