title: Clinical risk factors for failure in glaucoma tube surgery. A comparison of three tube designs.
abstract: We studied a cohort of 165 eyes that had undergone tube implant surgery for glaucoma, with a minimum follow-up of 12 months (range, 12 to 72 months). Of the 57 cases (34.5%) in which surgery failed to control intraocular pressure (less than 22 mm Hg), 15 (26%) occurred by 3 months, 36 (63%) by 12 months, and 46 (80%) by 24 months. Cox regression modeling was used to evaluate independent risk factors in the absence of additional therapy. The use of a two-piece (anterior chamber-to-encircling band) tube system was associated with a 2.4 times higher risk of failure (P less than .001) compared with a one-piece system. Neovascular glaucoma was associated with a 2.1 times higher risk of failure (P less than .037) than other types of glaucoma. Late failure of tube implant surgery is common and there is a steady attrition rate over a 2-year follow-up period.
authors.affiliation: Manchester Royal Eye Hospital, England.
authors.forename: M J
authors.initials: MJ
authors.lastname: Lavin
authors.forename: W A
authors.initials: WA
authors.lastname: Franks
authors.forename: R P
authors.initials: RP
authors.lastname: Wormald
authors.forename: R A
authors.initials: RA
authors.lastname: Hitchings
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D015999:Multivariate Analysis; D011183:Postoperative Complications; D016016:Proportional Hazards Models; D019736:Prostheses and Implants; D011475:Prosthesis Failure; D012086:Reoperation; D012189:Retrospective Studies; D012307:Risk Factors; D012826:Silicone Elastomers
chemical_list: D012826:Silicone Elastomers