title: The complete nucleotide sequence of the Atlantic salmon growth hormone I gene.
abstract: Two closely related genes encoding growth hormone were isolated from Atlantic salmon by genomic cloning. From one of these genes a total of 6500 nucleotides were determined including 3900 nucleotides in exons and introns and about 600 and 2000 nucleotides in 5' and 3' flanking regions. The gene is organized in six exons and encodes a polypeptide of 210 amino acids including a 22 amino acids signal sequence. The promoter region contains a typical TATA box 21 nucleotides upstream from the transcription start site. At the 3' end, three putative poly(A) signal sequences are present. The last two are within a 121 nt inverted repeat.
authors.affiliation: Center of Biotechnology, University of Bergen, Norway.
authors.forename: R
authors.initials: R
authors.lastname: Male
authors.forename: A H
authors.initials: AH
authors.lastname: Nerland
authors.forename: J B
authors.initials: JB
authors.lastname: Lorens
authors.forename: W
authors.initials: W
authors.lastname: Telle
authors.forename: I
authors.initials: I
authors.lastname: Lossius
authors.forename: G K
authors.initials: GK
authors.lastname: Totland
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015139:Blotting, Southern; D003001:Cloning, Molecular; D029941:Fish Proteins; D013006:Growth Hormone / Q000737:chemistry / Q000235:genetics*; D008969:Molecular Sequence Data; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics; D015183:Restriction Mapping; D012474:Salmon / Q000235:genetics*; D016415:Sequence Alignment
chemical_list: D029941:Fish Proteins; C074134:growth hormone type I, Salmo salar; D013006:Growth Hormone