title: Studies on biologically active complexes of cobalt(II) and nickel(II) with dithiooxamide-derived ligands.
abstract: A number of cobalt(II) and nickel(II) complexes with novel dithiooxamide ligands derived from precursors such as benzonitrile, benzosulfonamide, benzaldehyde, benzoic acid, and phenol have been synthesized and characterized on the basis of their elemental analysis molar conductance, magnetic moment, H NMR and electronic and IR spectral data. These ligands and their complexes have been screened for their antibacterial activities against bacterial species Staphylococcus aureus, Streptococcus pneumoniae, Escherichia coli, and Tuberculi bacilli. The studies indicate that in comparison to the ligands their metal complexes are more potent and antibacterial.
authors.affiliation: Department of Chemistry, Islamia University, Bahawalpur, Pakistan.
authors.forename: Z H
authors.initials: ZH
authors.lastname: Chohan
authors.forename: A
authors.initials: A
authors.lastname: Rauf
mesh_terms: D001419:Bacteria / Q000187:drug effects*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D003035:Cobalt / Q000737:chemistry* / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D009532:Nickel / Q000737:chemistry* / Q000494:pharmacology; D013055:Spectrophotometry, Infrared; D013211:Staphylococcus aureus / Q000187:drug effects; D013296:Streptococcus pneumoniae / Q000187:drug effects; D013854:Thioamides / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D013854:Thioamides; D003035:Cobalt; D009532:Nickel; C005728:rubeanic acid