title: [Scanning electron microscopic observation of the corneal endothelium in the Royal College of Surgeons rat].
abstract: The pathologic change in the cell surface of the corneal endothelium of the Royal College of Surgeons (RCS) rat is reported. Scanning electron microscopy (SEM) of 1-month-old RCS rat revealed several mushroom-like microvilli on the endothelial surface. In the 3-month-old RCS rat, the corneal endothelium had numerous filamentous microvilli, and some of the corneal endothelial cells had cytoplasmic edema. In the 6-month-old RCS rat, SEM showed numerous slender microvilli on the surface of corneal endothelium. These endothelial changes could be caused by the toxic substances generated from the degenerating retina.
authors.affiliation: Department of Ophthalmology, School of Medicine, Tohoku University, Sendai, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Yamaguchi
authors.forename: K
authors.initials: K
authors.lastname: Yamaguchi
authors.forename: J E
authors.initials: JE
authors.lastname: Turner
mesh_terms: D000818:Animals; D004728:Endothelium, Corneal / Q000648:ultrastructure*; D008855:Microscopy, Electron, Scanning; D008871:Microvilli / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains; D012162:Retinal Degeneration / Q000473:pathology