title: The multimeric pattern of von Willebrand's factor (vWF) can be demonstrated also in the severe form of the disease.
abstract: The multimeric analysis was carried out on the plasma of 18 patients with severe von Willebrand's disease (vWD) using two different types of agarose: Seakem HGT(P) and Seaplaque LGT. No pattern was found in any of the patients using Seakem HGT(P). On the contrary, by Seaplaque LGT, a multimeric pattern was found in four patients belonging to three different families, indicating that it is possible to identify and characterize variable multimeric patterns also in type III vWD.
authors.affiliation: Department of Haematology, Ospedale Niguarda Cà Granda, Milano, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Pezzetti
authors.forename: R
authors.initials: R
authors.lastname: Redaelli
authors.forename: T M
authors.initials: TM
authors.lastname: Caimi
authors.forename: D
authors.initials: D
authors.lastname: Cattaneo
authors.forename: F
authors.initials: F
authors.lastname: Baudo
authors.forename: F
authors.initials: F
authors.lastname: De Cataldo
mesh_terms: D001704:Biopolymers; D006801:Humans; D014842:von Willebrand Diseases / Q000097:blood*; D014841:von Willebrand Factor / Q000737:chemistry*
chemical_list: D001704:Biopolymers; D014841:von Willebrand Factor