title: Effect of starvation on glucose transport and membrane fluidity in rat intestinal epithelial cells.
abstract: Studies on the surface area of microvilli (MV), fluidity of brush border membranes (BBM) and D-glucose uptake were carried out in rat intestinal epithelial cells (IEC) during progressive starvation and under re-feed conditions. The surface area of MV, fluidity of BBM and D-glucose transport through IEC membranes showed an increase during starvation when compared to well-fed controls. Re-feeding experiments restored the control values of all the three parameters within a short time. The results showed that the increase in D-glucose transport through IEC membranes during starvation is due to increased surface area of MV and increased fluidity of BBM.
authors.affiliation: Centre for Cellular and Molecular Biology, Hyderabad, India.
authors.forename: P D
authors.initials: PD
authors.lastname: Gupta
authors.forename: A A
authors.initials: AA
authors.lastname: Waheed
mesh_terms: D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D001693:Biological Transport, Active / Q000502:physiology; D004848:Epithelium / Q000378:metabolism / Q000473:pathology; D005215:Fasting; D005947:Glucose / Q000378:metabolism*; D007421:Intestine, Small / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology; D008297:Male; D008560:Membrane Fluidity; D008871:Microvilli / Q000201:enzymology / Q000473:pathology; D011721:Pyrenes; D051381:Rats; D011919:Rats, Inbred Strains; D013217:Starvation / Q000201:enzymology / Q000378:metabolism* / Q000473:pathology
chemical_list: D011721:Pyrenes; C030984:pyrene; D000469:Alkaline Phosphatase; D005947:Glucose