Inactivation of the RAD1 excision-repair gene does not affect correction of mismatches on heteroduplex plasmid DNA in yeast.
The efficiency and direction of mismatch correction in the Saccharomyces cerevisiae SUP4-o gene were not altered by an excision-repair defect (rad1). Although excision-repair functions remove methylated adenine from yeast, adenine methylation at a GAC sequence in SUP4-o did not direct the correction of mismatches via excision repair.
Kang
X L
XL
Microbiology Department, University of Manitoba, Winnipeg, Canada.
Kunz
B A
BA
D000225:Adenine / Q000378:metabolism; D001482:Base Composition; D004260:DNA Repair / Q000235:genetics*; D004271:DNA, Fungal / Q000235:genetics*; D005800:Genes, Fungal / Q000502:physiology*; D016153:Genes, Suppressor / Q000235:genetics; D005822:Genetic Vectors; D008745:Methylation; D009154:Mutation; D009692:Nucleic Acid Heteroduplexes / Q000235:genetics*; D012343:RNA, Transfer / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D014170:Transformation, Genetic
D004271:DNA, Fungal; D009692:Nucleic Acid Heteroduplexes; D012343:RNA, Transfer; D000225:Adenine