title: Malignant rhabdoid tumor: primary intracranial manifestation in an adult.
abstract: Clinical, histopathological, and ultrastructural features of an extended intracranial malignant neoplasm are presented. Following incomplete extirpation of a large epidural tumor at the temporal base of the skull, the 21-year-old male patient suffered from several local recurrences and died at the age of 27. The neoplasm was defined by its histopathological and ultrastructural characteristics and by the pattern of its antigenicity as a malignant rhabdoid tumor (MRT). Considering previous publications on MRT, this case may be the first of primary intracranial MRT appearing in an adult.
authors.affiliation: Neurologisches Institut (Edinger-Institut), Universität Frankfurt/Main, Federal Republic of Germany.
authors.forename: M
authors.initials: M
authors.lastname: Horn
authors.forename: W
authors.initials: W
authors.lastname: Schlote
authors.forename: K D
authors.initials: KD
authors.lastname: Lerch
authors.forename: W I
authors.initials: WI
authors.lastname: Steudel
authors.forename: D
authors.initials: D
authors.lastname: Harms
authors.forename: E
authors.initials: E
authors.lastname: Thomas
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D007382:Intermediate Filaments / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D009364:Neoplasm Recurrence, Local; D014057:Tomography, X-Ray Computed