title: [The assessment of perinatal brain damage in premature infants at risk by serial creatine kinase BB measurements].
abstract: Peri-intraventricular bleeding (PIVH) is considered the most common cause of neurologic damage or death in low birthweight infants (less than 1000 g birth weight and 31 weeks of gestation). High-resolution real-time ultrasound scan is used for early diagnosis of PIVH in neonates. Furthermore, increase of serum creatine-kinase BB (CK-BB) values has been found to be clinically useful for diagnosis and prognosis of several perinatal cerebrovascular injuries. Eighty-eight preterm infants with different grades of PIVH (I-IV) were studied by serial measurements of CK-BB levels in serum. No statistical correlation was found between enzymatic levels and severity of PIVH (p greater than 0.5).
authors.affiliation: Institut für Neonatologie, Universität Bern, Schweiz.
authors.forename: M
authors.initials: M
authors.lastname: Amato
authors.forename: I
authors.initials: I
authors.lastname: Jäggi
authors.forename: P
authors.initials: P
authors.lastname: Hüppi
mesh_terms: D000704:Analysis of Variance; D001925:Brain Damage, Chronic / Q000175:diagnosis* / Q000453:epidemiology; D002543:Cerebral Hemorrhage / Q000175:diagnosis / Q000453:epidemiology; D016009:Chi-Square Distribution; D004796:Clinical Enzyme Tests; D003402:Creatine Kinase / Q000097:blood*; D004453:Echoencephalography; D005260:Female; D005865:Gestational Age; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D007234:Infant, Premature; D007527:Isoenzymes; D008297:Male; D012307:Risk Factors
chemical_list: D007527:Isoenzymes; D003402:Creatine Kinase
vernacular_title: Erfassung perinataler Hirnschäden bei Risiko-Frühgeborenen durch serielle Creatine-Kinase-BB-Messungen.