[Distribution of IGG antibodies to several phospholipids in patients with pulmonary thromboembolism].
Seven pulmonary thromboembolism cases with IgG antibodies to three phospholipids i.e. cardiolipin (CAR), phosphatidyl inositol(PI) or phosphatidyl serine(PS) were reported. We investigated the distribution of these antibodies in relation to clinical courses or clinical laboratory data. The cases had anti-phospholipid antibodies not only to CAR but also to PI or PS without regard to collagen disease cases or non-collagen disease cases. Two out of three collagen disease cases were positive to 2 antibodies among the measured 3 IgG antibodies. The two cases were chronic progressive, complicated with multiple thromboses, prolongation of blood coagulation time and decrease of platelet count. The other four non-collagen disease cases were positive to only 1 antibody among the 3 antibodies. Most of the 4 cases were acute and there were cases not complicated with multiple thromboses, prolongation of blood coagulation time or decrease of platelet count.
Ichinose
Y
Y
First Department of Internal Medicine, Tokyo Medical College.
Murakami
H
H
Kawano
K
K
Yamamoto
M
M
Ikeda
Y
Y
D000328:Adult; D000368:Aged; D001323:Autoantibodies / Q000032:analysis*; D003095:Collagen Diseases / Q000150:complications; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D010743:Phospholipids / Q000276:immunology*; D010976:Platelet Count; D011655:Pulmonary Embolism / Q000097:blood / Q000276:immunology*; D014914:Whole Blood Coagulation Time
D001323:Autoantibodies; D007074:Immunoglobulin G; D010743:Phospholipids