The penetration of drugs into the lesions of spinal tuberculosis.
The concentration of antituberculous drugs in blood and pus from tuberculous spinal lesions was measured initially, and again after 3 to 5 months of treatment in 4 cases. The pre- and post-chemotherapy drug concentrations were almost the same. This indicated that healing does not interfere with the penetration of the drugs into the lesion.
Kumar
K
K
Department of Orthopaedics, Krishna Institute of Medical Sciences, Karad Maharashtra State, India.
D000293:Adolescent; D000328:Adult; D000995:Antitubercular Agents / Q000493:pharmacokinetics* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D016659:Psoas Abscess / Q000188:drug therapy* / Q000378:metabolism; D013492:Suppuration / Q000378:metabolism; D014376:Tuberculosis / Q000188:drug therapy / Q000378:metabolism; D014399:Tuberculosis, Spinal / Q000188:drug therapy* / Q000378:metabolism
D000995:Antitubercular Agents