[The characteristics of the cardiovascular reactions in modelling a state of orthostatic hypotension in waking hypertensive animals].
This study demonstrates the suppression of chronotropic component and activation of vascular component of baroreceptor reflex evoked by v.cava inferior occlusion in the conscious chronically instrumented cats with renal hypertension. Infusion of nitroprusside caused the depression of both components in the normotensive and hypertensive animals. The values of system hemodynamics indices permit considering that new model of orthostatic hypotension is worked out.
Rozin
B D
BD
Iashina
L P
LP
Zhigalina
S G
SG
Medvedev
O S
OS
D000818:Animals; D002319:Cardiovascular System / Q000187:drug effects / Q000503:physiopathology*; D002415:Cats; D003864:Depression, Chemical; D004195:Disease Models, Animal; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D006973:Hypertension / Q000209:etiology / Q000503:physiopathology*; D007024:Hypotension, Orthostatic / Q000209:etiology / Q000503:physiopathology*; D008297:Male; D009392:Nephrectomy; D009599:Nitroprusside / Q000494:pharmacology; D014682:Vena Cava, Inferior / Q000502:physiology; D014851:Wakefulness / Q000187:drug effects / Q000502:physiology*
D009599:Nitroprusside
Issledovanie osobennosteĭ reaktsiĭ serdechno-sosudistoĭ sistemy pri modelirovanii sostoianiia ortostaticheskoĭ gipotonii u bodrstvuiushchikh gipertenzivnykh zhivotnykh.