title: Limb gangrene secondary to thromboembolic disease of the newborn.
abstract: Thromboembolic disease of the newborn is a well-known entity to neonatologists. When severe arterial compromise threatens limb survival, the orthopaedic surgeon may be called on to assist in the management of this disorder. A case of spontaneous postnatal ischemic gangrene of an upper extremity that resulted in amputation in a premature infant is presented; management options are discussed. Newborns are prone to thromboembolism due to a fibrinolytic capability that is significantly different from that of adults.
authors.affiliation: Department of Orthopedic Surgery, Medical College of Pennsylvania, Philadelphia.
authors.forename: S R
authors.initials: SR
authors.lastname: Askin
authors.forename: G
authors.initials: G
authors.lastname: Sullivan
authors.forename: K
authors.initials: K
authors.lastname: Dave
authors.forename: A
authors.initials: A
authors.lastname: Zubrow
authors.forename: N
authors.initials: N
authors.lastname: Razi
mesh_terms: D001132:Arm / Q000473:pathology; D002481:Cellulitis / Q000209:etiology* / Q000473:pathology; D005260:Female; D005734:Gangrene; D006801:Humans; D007231:Infant, Newborn; D012867:Skin / Q000473:pathology*; D012871:Skin Diseases / Q000209:etiology* / Q000473:pathology; D013923:Thromboembolism / Q000150:complications*