Beyond cold cardioplegia.
One hundred fifteen consecutive patients were operated on for myocardial revascularization or valvular disease or both with continuous antegrade and retrograde aerobic warm (37 degrees C) blood cardioplegia. Mean cross-clamp time was 56.3 +/- 21 minutes (+/- standard deviation). Mean reperfusion time was 18.4 +/- 11.8 minutes (range, 5 to 81 minutes). Five patients (4.3%) died, and 15 (13%) needed inotropic support. Two (1.7%) required intraaortic balloon support. Two patients (1.7%) had evidence of perioperative myocardial infarction, and 98 (85%) returned spontaneously to normal sinus rhythm. Sixteen patients had a cross-clamp time greater than 80 minutes. All 16 of them had an uneventful postoperative course except for 1 patient who required inotropic drugs. This method of myocardial protection is now used for all open heart procedures in our institution.
Lessana
A
A
Department of Cardiovascular Surgery, Hopital Europeen de Paris La Roseraie, France.
Romano
M
M
Singh
A I
AI
Le Houerou
D
D
Martin
V
V
Jegier
B
B
Palsky
E
E
Yu
H Q
HQ
Belli
E
E
Carbone
C
C
D000328:Adult; D000332:Aerobiosis; D000368:Aged; D000369:Aged, 80 and over; D001831:Body Temperature; D002302:Cardiac Output; D002303:Cardiac Output, Low / Q000209:etiology; D002314:Cardioplegic Solutions / Q000008:administration & dosage / Q000627:therapeutic use; D002315:Cardiopulmonary Bypass; D001026:Coronary Artery Bypass; D005260:Female; D006324:Heart Arrest, Induced / Q000379:methods*; D006349:Heart Valve Diseases / Q000601:surgery; D006801:Humans; D007423:Intra-Aortic Balloon Pumping; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D015425:Myocardial Reperfusion; D011446:Prospective Studies; D015996:Survival Rate; D013997:Time Factors
D002314:Cardioplegic Solutions