title: Apparent focal motor seizure with a jacksonian march induced by fentanyl: a case report and review of the literature.
abstract: This report describes an unusual presentation of focal motor activity resembling Jacksonian march, which developed during fentanyl induction of general anesthesia. Simultaneous spectral-edge activity recording of electroencephalography (EEG) failed to show evidence of an epileptic focus. A negative history of previous seizures, as well as failure to show postoperative postictal symptoms or seizure activity by 16-lead EEG, suggested a myoclonic rather than epileptic nature of the observed muscle activity. Pertinent literature and current theories regarding opioid-induced seizures are discussed.
authors.affiliation: Department of Anesthesiology, Medical College of Wisconsin, Milwaukee 53226.
authors.forename: J
authors.initials: J
authors.lastname: Sprung
authors.forename: H K
authors.initials: HK
authors.lastname: Schedewie
mesh_terms: D000368:Aged; D000768:Anesthesia, General; D016894:Endarterectomy, Carotid; D004828:Epilepsies, Partial / Q000139:chemically induced*; D005283:Fentanyl / Q000009:adverse effects*; D006801:Humans; D009207:Myoclonus / Q000139:chemically induced*
chemical_list: D005283:Fentanyl