title: Opsonophagocytosis of Pneumocystis carinii.
abstract: The interaction of Pneumocystis carinii purified from rat lungs with rat peritoneal macrophages and human circulating polymorphonuclear leucocytes was studied by amplified chemiluminescence and examination of stained cytospin preparations. A polyclonal rat antiserum to P. carinii was opsonic with both types of phagocyte. Complement had no opsonic properties alone but produced a synergic effect in combination with antibody.
authors.affiliation: Department of Medical Microbiology, Wright Fleming Institute, St Mary's Hospital Medical School, London.
authors.forename: M B
authors.initials: MB
authors.lastname: Taylor
authors.forename: M
authors.initials: M
authors.lastname: Phillips
authors.forename: C S
authors.initials: CS
authors.lastname: Easmon
mesh_terms: D000818:Animals; D000908:Antibodies, Fungal / Q000276:immunology; D003165:Complement System Proteins / Q000276:immunology; D005260:Female; D006801:Humans; D007106:Immune Sera / Q000276:immunology; D008264:Macrophages / Q000276:immunology*; D008297:Male; D009504:Neutrophils / Q000276:immunology*; D009895:Opsonin Proteins / Q000276:immunology*; D010587:Phagocytosis; D011010:Pneumocystis / Q000276:immunology*; D051381:Rats; D011917:Rats, Inbred Lew; D011919:Rats, Inbred Strains
chemical_list: D000908:Antibodies, Fungal; D007106:Immune Sera; D009895:Opsonin Proteins; D003165:Complement System Proteins