Endothelial cells in hemostasis, thrombosis, and inflammation.
Once regarded as an inert lining, the vascular endothelium is now known to synthesize a variety of molecules that can protect against or promote disease. These important agents include prostacyclin, thrombomodulin, plasminogen activators, and ecto-enzymes. Our growing understanding of their protective and pathologic roles has already provided new therapeutic strategies.
Wu
K K
KK
University of Texas, Houston.
D001809:Blood Viscosity / Q000502:physiology; D004211:Disseminated Intravascular Coagulation / Q000503:physiopathology; D004730:Endothelium, Vascular / Q000166:cytology / Q000502:physiology*; D006487:Hemostasis / Q000502:physiology*; D006801:Humans; D011697:Purpura, Thrombotic Thrombocytopenic / Q000503:physiopathology; D013927:Thrombosis / Q000503:physiopathology*; D014657:Vasculitis / Q000503:physiopathology*; D014661:Vasoconstriction / Q000502:physiology