title: Inheritance of hydrocephalus in horses.
abstract: From 1974 to 1979, seven stillborn foals with internal hydrocephalus were encountered from one Standardbred trotter stallion which sired 239 registered foals. An hydrocephalic foal was also aborted by a daughter of the same stallion. One affected foal from Standardbred trotters and one from a Finnish Horses were also reported. In some cases, the condition caused severe dystocia. Based on field data, possible causes of the defect could neither be proved nor specifically overruled in individual cases. Hydrocephalus was obviously not an autosomal recessive single-locus defect, nor was it X-linked. A dominant mutation in the germ line in one of the parents or in any embryo seemed the most likely explantation for the occurrence of internal hydrocephalus in horses.
authors.affiliation: Department of Animal Breeding, University of Helsinki, Finland.
authors.forename: M
authors.initials: M
authors.lastname: Ojala
authors.forename: J
authors.initials: J
authors.lastname: Ala-Huikku
mesh_terms: D000818:Animals; D001947:Breeding; D005260:Female; D005799:Genes, Dominant; D006734:Horse Diseases / Q000235:genetics*; D006736:Horses; D006849:Hydrocephalus / Q000235:genetics / Q000662:veterinary*; D008297:Male; D009154:Mutation; D010375:Pedigree