Treatment of nummular psoriasis with a clobetasol propionate stick.
Twenty-two consecutive patients with nummular psoriasis were treated with a 0.05% clobetasol propionate stick on the right side of the body and with 0.05% clobetasol propionate ointment (Dermovate, Glaxo) on the left according to an intermittent application schedule. The trial was open and lasted for 3 weeks. The patients were assessed at the beginning and at the end of the trial. The variables studied included: an overall clinical assessment, assessment of the lesion area, scaling, erythema and thickness and the amount of clobetasol propionate used during the trial, and a questionnaire on patients' opinions about hygienic and cosmetic qualities of the stick. No significant difference was found between the stick and corresponding ointment. From a hygienic and cosmetic point of view, the patients preferred the stick formulation.
Bergstedt
C
C
Department of Dermatology, Varberg Hospital, Sweden.
Gamborg Nielsen
P
P
Karlsson
L
L
Strömberg
L
L
D000293:Adolescent; D000328:Adult; D000368:Aged; D002990:Clobetasol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004304:Dosage Forms; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009824:Ointments; D011565:Psoriasis / Q000188:drug therapy* / Q000473:pathology
D004304:Dosage Forms; D009824:Ointments; D002990:Clobetasol