Growth patterns of ovarian follicles during induction of ovulation with decreasing doses of human menopausal gonadotropin following presumed selection in polycystic ovary syndrome.
Data presented in this study indicate that ovulation can be induced in patients with PCOS using a GnRH analogue combined with hMG in a decreasing dose regimen. Based on the observed decline in functional, medium sized follicles in the late follicular phase, it may be speculated that the risk of ovarian hyperstimulation during gonadotropin induction of ovulation in patients with PCOS can be reduced.
Schoot
D C
DC
Department of Obstetrics and Gynecology A, Dijkzigt University Hospital, Rotterdam, The Netherlands.
Pache
T D
TD
Hop
W C
WC
de Jong
F H
FH
Fauser
B C
BC
D000328:Adult; D002064:Buserelin / Q000627:therapeutic use; D004334:Drug Administration Schedule; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007247:Infertility, Female / Q000628:therapy; D008596:Menotropins / Q000008:administration & dosage* / Q000627:therapeutic use; D006080:Ovarian Follicle / Q000000981:diagnostic imaging / Q000502:physiology*; D010062:Ovulation Induction; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000503:physiopathology*; D011897:Random Allocation; D014463:Ultrasonography
D008596:Menotropins; D005640:Follicle Stimulating Hormone; D002064:Buserelin