title: Frontal, temporal, and striatal proton relaxation times in schizophrenic patients and normal comparison subjects.
abstract: Spin-lattice (T1) and spin-spin (T2) magnetic resonance relaxation times were examined in frontal, temporal, and striatal regions of 24 patients with schizophrenia and 10 normal comparison subjects. The schizophrenic patients had more prolonged T2 values than did the comparison subjects, particularly in the left temporal cortex and white matter, suggesting tissue pathology.
authors.affiliation: Department of Psychiatry, University of Western Ontario, London, Canada.
authors.forename: P
authors.initials: P
authors.lastname: Williamson
authors.forename: D
authors.initials: D
authors.lastname: Pelz
authors.forename: H
authors.initials: H
authors.lastname: Merskey
authors.forename: S
authors.initials: S
authors.lastname: Morrison
authors.forename: S
authors.initials: S
authors.lastname: Karlik
authors.forename: D
authors.initials: D
authors.lastname: Drost
authors.forename: T
authors.initials: T
authors.lastname: Carr
authors.forename: P
authors.initials: P
authors.lastname: Conlon
mesh_terms: D000328:Adult; D001479:Basal Ganglia / Q000473:pathology; D003342:Corpus Striatum / Q000473:pathology*; D005260:Female; D005625:Frontal Lobe / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000175:diagnosis* / Q000473:pathology; D013702:Temporal Lobe / Q000473:pathology*