Comparative observation of the changes in serum lipid peroxides influenced by the supplementation of vitamin E in burn patients and healthy controls.
A microfluorescence analytical method was used to determine the contents of serum lipid peroxides and vitamin E in 35 severely burned patients, among whom 18 had been given vitamin E, and in 113 healthy blood donors. A comparative survey showed that the serum vitamin E decreased most significantly from days 6 to 8 postburn in both groups of burned patients, while the concomitant serum lipid peroxides increased significantly and reached a peak value. In control patients, the serum vitamin E levels were lower and lipid peroxides higher than those of healthy people (P less than 0.05) from days 20 to 22 postburn. At this time in the vitamin E-treated patients, the serum vitamin E levels increased and lipid peroxides decreased to the levels of healthy people (P greater than 0.05). Therefore, appropriate supplementation with vitamin E in burn patients is necessary.
Zhang
M J
MJ
First Central Hospital, Academy of Military Medical Sciences, Tianjin, PR China.
Wang
Q F
QF
Gao
L X
LX
Jin
H
H
Wang
Z Y
ZY
D000293:Adolescent; D000328:Adult; D002056:Burns / Q000097:blood*; D003592:Cytophotometry; D005260:Female; D006801:Humans; D008054:Lipid Peroxides / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011897:Random Allocation; D014810:Vitamin E / Q000008:administration & dosage*
D008054:Lipid Peroxides; D014810:Vitamin E