title: Chediak-Higashi syndrome in a black child.
abstract: Chediak-Higashi syndrome (CHS) is an uncommon genetic disorder with a constellation of clinical, pathologic, and immunologic manifestations. It is rarely reported in blacks. Pathognomonic intracellular inclusions in white blood cells are well recognized; however, characteristic abnormal melanin aggregation into giant melanosomes also occurs, as can be readily seen by histologic evaluation of hair. We present a case of CHS in a black child.
authors.affiliation: Department of Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas.
authors.forename: L L
authors.initials: LL
authors.lastname: Anderson
authors.forename: A S
authors.initials: AS
authors.lastname: Paller
authors.forename: D
authors.initials: D
authors.lastname: Malpass
authors.forename: M L
authors.initials: ML
authors.lastname: Schmidt
authors.forename: T G
authors.initials: TG
authors.lastname: Berger
mesh_terms: D044383:Black People; D002609:Chediak-Higashi Syndrome / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D007223:Infant; D008297:Male; D014481:United States / Q000453:epidemiology; D001741:Black or African American