title: Case report: treatment of blastomycosis with fluconazole.
abstract: The authors present two cases of systemic blastomycosis successfully treated with fluconazole. In one case, the disease involved the respiratory tract, and the central nervous system was presumed to be involved. The second case consisted only of pulmonary blastomycosis. Both patients were treated with oral fluconazole 200 mg twice per day for 9 and 6 months, respectively. Treatment with this new triazole antifungal agent resulted in the complete resolution of the disease in both patients. They have remained asymptomatic for more than 6 months after the completion of therapy.
authors.affiliation: Department of Pharmaceutical Services, St. Joseph Health Centre, Toronto, Ontario.
authors.forename: G J
authors.initials: GJ
authors.lastname: Pearson
authors.forename: T W
authors.initials: TW
authors.lastname: Chin
authors.forename: I W
authors.initials: IW
authors.lastname: Fong
mesh_terms: D000328:Adult; D001759:Blastomycosis / Q000188:drug therapy*; D015725:Fluconazole / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012141:Respiratory Tract Infections / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed
chemical_list: D015725:Fluconazole