Conservation of receptor expression and phagocytic activity of murine macrophages exposed to various ultrasonic regimens in vitro.
Murine peritoneal macrophages insonated in vitro at 37 degrees C were assayed for impairment of adhesion to and spreading on glass coverslips, expressions of Fc gamma and C3b receptors, and phagocytosis. Insonation conditions were typical for exposures by B-mode imaging equipment and approximated the most severe exposures anticipated in use of pulsed Doppler equipment. In no case were the assay results for insonated samples significantly different from those for the sham-exposed controls.
Prohaska
S S
SS
Department of Cellular and Biochemical Technology, SRI International, Menlo Park, CA 94025.
Rimer
V G
VG
Winters
M A
MA
Humphres
R C
RC
Tusé
D
D
Edmonds
P D
PD
D000818:Animals; D002448:Cell Adhesion / Q000502:physiology; D002465:Cell Movement / Q000502:physiology; D002470:Cell Survival / Q000502:physiology; D003179:Complement C3b / Q000502:physiology; D005260:Female; D066298:In Vitro Techniques; D008264:Macrophages / Q000000981:diagnostic imaging*; D051379:Mice; D008807:Mice, Inbred BALB C; D010529:Peritoneal Cavity / Q000000981:diagnostic imaging; D010587:Phagocytosis / Q000502:physiology*; D011951:Receptors, Complement / Q000502:physiology*; D011961:Receptors, Fc / Q000502:physiology*; D014463:Ultrasonography
D011951:Receptors, Complement; D011961:Receptors, Fc; D003179:Complement C3b