Interpretation of cardiac pathophysiology from pressure waveform analysis: effects of nitroglycerin.
Nitroglycerin has dependable, short-lived veno- and arterial vasodilatory effects ameliorating ischemia through both preload reduction and coronary vasodilation. Nitroglycerin should be used prior to left ventriculography in patients with elevated left ventricular end-diastolic pressure. The arterial pressure waveform alteration of nitroglycerin can be explained on the basis of changes in arterial distensibility and reflected wave patterns and may vary considerably among individuals with different degrees of atherosclerosis.
Kern
M J
MJ
St. Louis University Hospital, Missouri 63110.
Aguirre
F V
FV
Hilton
T C
TC
D000368:Aged; D000789:Angina, Unstable / Q000503:physiopathology; D001024:Aortic Valve Stenosis / Q000188:drug therapy; D001794:Blood Pressure / Q000187:drug effects; D003326:Coronary Circulation / Q000187:drug effects; D003327:Coronary Disease / Q000503:physiopathology*; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000494:pharmacology* / Q000627:therapeutic use; D014664:Vasodilation / Q000187:drug effects
D005996:Nitroglycerin