Progress of brown tumors in patients with chronic renal insufficiency undergoing dialysis.
In a group of 73 patients, affected by chronic renal insufficiency, whose skeleton was periodically checked, three cases of brown tumors were found. These cases demonstrated a variety of locations that were involved, especially the pelvis, ribs and mandible. During therapeutic treatment the brown tumors presented a different behavior; while some lesions tended toward complete sclerosis, others increased in size and in both instances new lesions appeared. Parathyroidectomy, carried out in two patients, determined a definitive sclerosis of these lesions. Brown tumors also correlate with high PTH levels and with lesions from osteitis fibrosa.
Marini
M
M
Departement of Expermental Medicine, University of Rome La Sapienza, Italy.
Vidiri
A
A
Guerrisi
R
R
Campodonico
F
F
Ponzio
R
R
D000293:Adolescent; D000328:Adult; D000368:Aged; D001847:Bone Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006101:Granuloma, Giant Cell / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010002:Osteitis Fibrosa Cystica / Q000000981:diagnostic imaging / Q000473:pathology; D010014:Osteolysis / Q000000981:diagnostic imaging / Q000473:pathology; D010026:Osteosclerosis / Q000000981:diagnostic imaging / Q000473:pathology; D011859:Radiography; D006435:Renal Dialysis; D012189:Retrospective Studies