X-ray diffraction by collagen in the fully mineralized cortical bone of cow tibia.
X-ray diffraction patterns were recorded from fully mineralized and demineralized sections of the cortical bone from cow tibia. The results were used to obtain a measure, d, of the mean side-to-side spacing (equatorial diffraction spacing) of the molecules in the type I collagen fibrils of bone. Mineralized bone yielded a d value of 1.23 nm; for the demineralized tissue this value increased to 1.52 nm. Thus it appears that mineralization of bone compacts its collagen molecules within the fibrils.
Lees
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Bioengineering Department, Forsyth Dental Center, Boston, MA 02115.
Hukins
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D000818:Animals; D001842:Bone and Bones / Q000737:chemistry*; D002113:Calcification, Physiologic; D002417:Cattle; D003094:Collagen / Q000032:analysis*; D013977:Tibia; D014961:X-Ray Diffraction
D003094:Collagen