title: Gliofibroma: immunohistochemical analysis.
abstract: A case of gliofibroma occurring in an adult patient as a large circumscribed supratentorial tumor is reported. The bimorphic pattern was substantiated and further analyzed by immunohistochemistry. Some evidence in favor of collagen production by mesenchymal and/or inflammatory cells leading to a progressive fibrous replacement of the glial cells in this particular tumor type is presented.
authors.affiliation: Abteilung für Neuropathologie, Heinrich-Heine-Universität, Düsseldorf, Federal Republic of Germany.
authors.forename: R
authors.initials: R
authors.lastname: Schober
authors.forename: C
authors.initials: C
authors.lastname: Bayindir
authors.forename: A
authors.initials: A
authors.lastname: Canbolat
authors.forename: H
authors.initials: H
authors.lastname: Urich
authors.forename: W
authors.initials: W
authors.lastname: Wechsler
mesh_terms: D000293:Adolescent; D005910:Glioma / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D008854:Microscopy, Electron; D015173:Supratentorial Neoplasms / Q000473:pathology* / Q000648:ultrastructure