title: DNA sequencing of four bases using three lanes.
abstract: A three-lane DNA sequencing strategy is described which is based on redundant binary coding principles from communications theory. Three-lane sequencing is an efficient, accurate, and flexible strategy, suitable for large-scale automated DNA sequencing. Communications theory and algebraic coding principles can also be applied to sequencing other informational macromolecules.
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Chicago, IL 60637.
authors.forename: M
authors.initials: M
authors.lastname: Nelson
authors.forename: J L
authors.initials: JL
authors.lastname: Van Etten
authors.forename: R
authors.initials: R
authors.lastname: Grabherr
mesh_terms: D001482:Base Composition; D001483:Base Sequence; D003198:Computer Simulation; D004247:DNA / Q000737:chemistry*; D005821:Genetic Techniques
chemical_list: D004247:DNA