[Peranal ulcers caused by ergotamine-containing suppositories].
Perianal ulcerations caused by suppositories application is an exceptional situation. We describe a 64 years old female with recurrent painless perianal ulcerations evoluting from 14 months. She medicates herself daily, since 8 to 10 years, with ergotamine tartarate suppositories, for the treatment of migraine. The diagnosis of ulcerated cutaneous drug reaction induced by ergotamine tartarate was confirmed by the complete healing of the lesions after stopping this medication and by their recurrence after the reintroduction of the treatment. These ulcerations are probably due to vasospasm of regional arterioles.
Baptista
A P
AP
Serviço de Dermatologia, Hospitais da Universidade de Coimbra.
Mariano
A
A
Machado
A
A
D001004:Anus Diseases / Q000139:chemically induced*; D004878:Ergotamine / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D013488:Suppositories; D014456:Ulcer / Q000139:chemically induced
D013488:Suppositories; D004878:Ergotamine
Ulcerações perianais por supositórios contendo ergotamina.