Ovarian hyperstimulation and follicular aspiration. Effect on ovulatory function.
The return of normal function of the reproductive axis immediately after hyperstimulation and follicular aspiration is of both physiologic and clinical interest. These cycles may be utilized for the replacement of cryopreserved embryos, for repeated ovarian stimulation or for any alternative treatment that relies upon normal ovulatory function. Thirty-five women were randomly assigned to be monitored in the first (n = 11), second (n = 13) or third (n = 11) menstrual cycle after in vitro fertilization (IVF). Five of 35 patients (14.3%) failed to ovulate, 2 in each of the first and second menstrual cycles and 1 in the third cycle after IVF. Six (20%) ovulatory cycles demonstrated luteal phase deficiencies. The defective luteal phases were evenly distributed between cycles immediately after IVF and those more remote in time from the procedure.
Grunfeld
L
L
Department of Obstetrics and Gynecology and Reproductive Science, Mount Sinai Medical Center, New York, New York.
Sandler
B
B
Fox
J H
JH
Williams
M
M
Navot
D
D
D000046:Academic Medical Centers; D000328:Adult; D000858:Anovulation / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D004958:Estradiol / Q000097:blood; D005260:Female; D006801:Humans; D015994:Incidence; D007247:Infertility, Female / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D008183:Luteal Phase; D007986:Luteinizing Hormone / Q000097:blood; D009519:New York City / Q000453:epidemiology; D016471:Ovarian Hyperstimulation Syndrome / Q000150:complications*; D010062:Ovulation Induction / Q000009:adverse effects*; D011374:Progesterone / Q000097:blood; D014463:Ultrasonography
D011374:Progesterone; D004958:Estradiol; D007986:Luteinizing Hormone