The recovery of the ultrastructure of hyperchromic host neurons under the influence of fetal neurotransplants.
Fetal neocortical transplants placed into a previously prepared cavity in the cortex of adult animals inhibited destructive processes in host neurons surrounding the place of injury. This was demonstrated by a gradual reduction in the number of hyperchromic and shrunken host neurons and the recovery of the ultrastructure of dystrophic cells which die as a result of neuronophagia or sclerosis in the absence of the transplants.
Kleshchinov
V N
VN
Laboratory of Experimental Neurogenetics, N.I. Vavilov Institute of General Genetics, USSR Academy of Sciences, Moscow.
Alexandrova
M
M
D000818:Animals; D001253:Astrocytes / Q000648:ultrastructure; D016380:Brain Tissue Transplantation / Q000502:physiology*; D002467:Cell Nucleus / Q000648:ultrastructure; D005260:Female; D016332:Fetal Tissue Transplantation / Q000502:physiology*; D008854:Microscopy, Electron; D009457:Neuroglia / Q000648:ultrastructure; D009474:Neurons / Q000648:ultrastructure*; D051381:Rats; D011919:Rats, Inbred Strains; D013003:Somatosensory Cortex / Q000276:immunology / Q000648:ultrastructure