Typing and screening of blood from intraosseous access.
OBJECTIVE
To determine if intramedullary aspirate from intraosseous needle placement can be used as a source for evaluating blood compatibility.


METHODS
A prospective, nonrandomized, crossover study.


METHODS
Patients admitted to the hematology/oncology service undergoing bone marrow aspiration for medical purposes.


METHODS
Patients had simultaneous samples of bone marrow aspiration from the posterior iliac crest and peripheral venous blood drawn and sent for typing and screening.


RESULTS
The paired samples were evaluated for ABO and Rh typing as well as the presence of human leukocyte activity by evaluating the reaction strength between the marrow and venous samples.


RESULTS
No differences were seen in the reaction strength between the paired samples in any subjects for ABO and Rh typing (P = .90, yielding beta = .0523). In addition, human leukocyte activity was detected in both the marrow and venous samples in one patient.


CONCLUSIONS
Bone marrow aspirates following intraosseous infusion can be used for accurate and reliable typing and screening of blood.
Brickman
K R
KR
St Vincent Medical Center, Toledo Hospital, Ohio.
Krupp
K
K
Rega
P
P
Alexander
J
J
Guinness
M
M
D000017:ABO Blood-Group System / Q000302:isolation & purification; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001788:Blood Grouping and Crossmatching / Q000379:methods*; D001853:Bone Marrow; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies; D012204:Rh-Hr Blood-Group System / Q000302:isolation & purification
D000017:ABO Blood-Group System; D012204:Rh-Hr Blood-Group System