Netilmycin and vancomycin in the treatment of peritonitis in CAPD patients.
This study was undertaken to evaluate: 1. The efficacy of netilmycin and vancomycin as combined first line antimicrobial regime, compared to cefuroxime, in the treatment of peritonitis. 2. To measure the levels of netilmycin and vancomycin in the serum and dialysate. 3. To report on the use of this combination over a one year period and compare it with that of cefuroxime used during the previous one year.
Were
A J
AJ
Department of Renal Medicine, Manchester Royal Infirmary, UK.
Marsden
A
A
Tooth
A
A
Ramsden
R
R
Mistry
C D
CD
Gokal
R
R
D000328:Adult; D000368:Aged; D002444:Cefuroxime / Q000627:therapeutic use; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009428:Netilmicin / Q000493:pharmacokinetics / Q000627:therapeutic use*; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*; D010538:Peritonitis / Q000188:drug therapy* / Q000382:microbiology; D010865:Pilot Projects; D011897:Random Allocation; D013203:Staphylococcal Infections / Q000188:drug therapy*; D014640:Vancomycin / Q000493:pharmacokinetics / Q000627:therapeutic use*
D009428:Netilmicin; D014640:Vancomycin; D002444:Cefuroxime