title: [Our experience in surgery of metastases of parenchymal renal neoplasms: mean follow-up time results].
abstract: The Authors report their experience about surgical treatment of metastases from renal cell carcinoma. From January 1983 to December 1989, twenty eight patients, 19 males and 9 females, with a median age of 58 years (range 42-79), have been submitted to contemporary or subsequent metastasectomy. Metastases were synchronous in 10 cases, while they appeared after a free disease mean-time of 28 months after nephrectomy in 18 patients. Recovery period has always been normal and all the patients were controlled, every six months, with routine blood and urine examinations, Chest X-ray, abdominal CAT and bone scan. Among the 10 patients with synchronous metastases 5 died, 3 are in progression and 2 are NED after a mean-time follow up of 36 months. Among 18 patients who underwent surgery for metachronous metastases, 2 died, 4 are in progression and 12 NED (mean follow up of 36 months). In conclusion, while the presence of synchronous metastases is an unfavourable prognostic factor even after their surgical removal (8 out of 10 patients died or are in progression shortly after metastasectomy), results after metachronous metastases surgery are encouraging, but the real efficiency of this treatment is still to be confirmed.
authors.affiliation: Divisione Clinicizzata di Urologia, Università di Brescia.
authors.forename: A
authors.initials: A
authors.lastname: Cozzoli
authors.forename: E
authors.initials: E
authors.lastname: Frego
authors.forename: G
authors.initials: G
authors.lastname: Cancarini
authors.forename: A
authors.initials: A
authors.lastname: Giongo
authors.forename: S
authors.initials: S
authors.lastname: Cosciani Cunico
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000556:secondary / Q000601:surgery*; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000556:secondary / Q000601:surgery*; D002292:Carcinoma, Renal Cell; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms; D008175:Lung Neoplasms / Q000556:secondary / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D013997:Time Factors
vernacular_title: Nostra esperienza nella chirurgia delle metastasi da neoplasia renale parenchimale: risultati a medio termine.