Carbon-13 magnetic resonance in biology and medicine.
C-13 magnetic resonance spectroscopy is becoming an important tool for the investigation of metabolic processes either in vitro or in vivo. In this review we discuss some methodological aspects of C-13 magnetic resonance spectroscopy and recent applications of this technique to the study of beta-oxidation of fatty acids in the liver and intermediary metabolism in the brain. Finally, two promising applications in the field of clinical investigation are discussed.
Seelig
J
J
Department of Biophysical Chemistry, University of Basel, Switzerland.
Burlina
A P
AP
D000818:Animals; D001921:Brain / Q000378:metabolism*; D002087:Butyrates / Q000378:metabolism; D002247:Carbon Isotopes; D003920:Diabetes Mellitus / Q000378:metabolism; D005215:Fasting / Q000378:metabolism; D005947:Glucose / Q000378:metabolism; D006801:Humans; D008099:Liver / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008297:Male; D051381:Rats
D002087:Butyrates; D002247:Carbon Isotopes; D005947:Glucose