Skeletal scintigraphy of pseudo-osteomyelitis in Gaucher's disease. Two case reports and a review of the literature.
Two patients with known type 1 Gaucher's disease had signs and symptoms of osteomyelitis. Decreased perfusion and impaired uptake were seen on bone scan. Patient 1 had a culture-negative aspirate of the site. Patient 2 had no surgical procedures. Both improved on bed rest and nonsteroidal anti-inflammatory agents. It is difficult to distinguish osteomyelitis clinically from pseudo-osteomyelitis. The authors suggest that photopenia on bone scan performed within 1 to 3 days of presentation is suggestive of pseudo-osteomyelitis in Gaucher's disease.
Bilchik
T R
TR
Department of Nuclear Medicine, Hospital of the University of Pennsylvania, Philadelphia.
Heyman
S
S
D001842:Bone and Bones / Q000000981:diagnostic imaging*; D002648:Child; D005260:Female; D005710:Gallium Radioisotopes; D005776:Gaucher Disease / Q000150:complications / Q000000981:diagnostic imaging*; D006801:Humans; D010019:Osteomyelitis / Q000000981:diagnostic imaging* / Q000209:etiology; D011877:Radionuclide Imaging
D005710:Gallium Radioisotopes