Inhibition of natural antibody synthesis by cyclophosphamide or 15-deoxyspergualin fails to prevent xenograft rejection in the guinea pig-to-rat model.
Leventhal
J R
JR
University of Minnesota Hospital and Clinic, Minneapolis 55455.
Platt
J L
JL
Flores
H C
HC
Gruber
S A
SA
Matas
A J
AJ
Bolman
R M
RM
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D003176:Complement C3 / Q000032:analysis; D003520:Cyclophosphamide / Q000494:pharmacology*; D006084:Graft Rejection / Q000187:drug effects*; D006085:Graft Survival / Q000187:drug effects*; D006146:Guanidines / Q000494:pharmacology*; D006168:Guinea Pigs; D016027:Heart Transplantation / Q000276:immunology*; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D051381:Rats; D011917:Rats, Inbred Lew; D014183:Transplantation, Heterologous / Q000276:immunology*
D003176:Complement C3; D006146:Guanidines; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; C037258:gusperimus