title: A comparison of sample size methods for the logrank statistic.
abstract: Several methods are available for sample size calculation for clinical trials when survival curves are to be compared using the logrank statistic. We discuss advantages and disadvantages of some of these methods, and present simulation results under exponential, proportional hazards and non-proportional hazard situations.
authors.affiliation: Biostatistics Research Branch, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20892.
authors.forename: E
authors.initials: E
authors.lastname: Lakatos
authors.forename: K K
authors.initials: KK
authors.lastname: Lan
mesh_terms: D002986:Clinical Trials as Topic; D003198:Computer Simulation; D006801:Humans; D008962:Models, Theoretical; D012107:Research Design; D013223:Statistics as Topic; D016019:Survival Analysis