title: Effects of zopiclone on subjective evaluation of sleep and daytime alertness and on psychomotor and physical performance tests in athletes.
abstract: 1. In a double-blind cross-over study 8 athletes received during 2 sessions of 2 nights zopiclone (7.5 mg) or placebo. 2. Residual effects on subsequent daytime functions were evaluated both subjectively by visual analogue scales as well as objectively by a test battery measuring psychomotor and physical skills. 3. Zopiclone had some favourable effects on self-estimated sleep quality and daytime sleepiness. 4. Psychomotor and physical performance tests did not show any significant difference between zopiclone and placebo. 5. We conclude that zopiclone has useful hypnotic activity without significant adverse effects on athletic performance.
authors.affiliation: Sleep & Wake Disorders Unit, Gui de Chauliac Hospital, Montpellier, France.
authors.forename: M
authors.initials: M
authors.lastname: Tafti
authors.forename: A
authors.initials: A
authors.lastname: Besset
authors.forename: M
authors.initials: M
authors.lastname: Billiard
mesh_terms: D000328:Adult; D001288:Attention / Q000187:drug effects*; D053961:Azabicyclo Compounds; D004311:Double-Blind Method; D005425:Flicker Fusion / Q000187:drug effects; D006801:Humans; D006993:Hypnotics and Sedatives / Q000494:pharmacology*; D008297:Male; D010879:Piperazines / Q000494:pharmacology*; D011597:Psychomotor Performance / Q000187:drug effects*; D011930:Reaction Time / Q000187:drug effects; D012420:Running; D012890:Sleep / Q000187:drug effects*; D013177:Sports / Q000523:psychology
chemical_list: D053961:Azabicyclo Compounds; D006993:Hypnotics and Sedatives; D010879:Piperazines; C515050:zopiclone