title: Stimulation of granulopoiesis in pregnant swine and their offspring by Propionibacterium avidum KP-40.
abstract: Functional parameters of granulopoiesis were measured in gilts, in pregnant sows and in their offspring. Groups of dams and piglets were injected with a potent immunomodulator--killed lyophilized Propionibacterium avidum KP-40 (PA). Administration of PA (0.1 mg/kg body wt for sows and 0.2 mg/kg body wt for piglets) resulted in significant stimulation of all measured parameters of granulopoiesis as well as in a faster gain of body weight. PA stimulation of sows prior to farrowing had no measurable influence on the development of their offspring.
authors.affiliation: Department of Swine Diseases, Veterinary Research Institute, Pulawy, Poland.
authors.forename: I
authors.initials: I
authors.lastname: Markowska-Daniel
authors.forename: Z
authors.initials: Z
authors.lastname: Pejsak
authors.forename: S
authors.initials: S
authors.lastname: Szmigielski
authors.forename: J
authors.initials: J
authors.lastname: Jeljaszewicz
authors.forename: G
authors.initials: G
authors.lastname: Pulverer
mesh_terms: D000276:Adjuvants, Immunologic; D000818:Animals; D005260:Female; D006098:Granulocytes; D006410:Hematopoiesis; D011247:Pregnancy; D011424:Propionibacterium / Q000276:immunology*; D011897:Random Allocation; D013552:Swine / Q000276:immunology*
chemical_list: D000276:Adjuvants, Immunologic