title: [Myocardial scintigraphy with technetium 99m methoxyisobutylisonitrile. A comparison with coronary arteriography in patients with suspected ischemic cardiopathy].
abstract: Technetium-99m methoxy-isobutyl-isonitrile (MIBI) myocardial scintigraphy has been proposed as an alternative to Thallium 201 myocardial imaging in the evaluation of patients with coronary artery diseases. We studied 39 patients (37 men, mean age 56 +/- 9 years) with suspected coronary artery disease. All patients underwent 99mTc MIBI myocardial scintigraphy after stress and at rest. Coronary arteriography, performed within 1 month, showed significant (greater than or equal to 50%) stenosis of at least 1 epicardial coronary artery in 36 subjects. 99mTc MIBI myocardial scintigraphy exhibited 94% sensitivity (34/36 patients) and 100% specificity (3/3 subjects with normal coronary arteries). Sensitivity for individual vessel stenosis was 81% (96% for the left anterior descending artery, 65% for the circumflex artery and 79% for the right artery). Our data show that 99mTc MIBI myocardial scintigraphy is capable of evaluating patients with coronary artery diseases.
authors.affiliation: Cattedra di Medicina Nucleare, II Facoltà di Medicina, Università Federico II, Napoli.
authors.forename: L
authors.initials: L
authors.lastname: Pace
authors.forename: A
authors.initials: A
authors.lastname: Cuocolo
authors.forename: A
authors.initials: A
authors.lastname: Nappi
authors.forename: E
authors.initials: E
authors.lastname: Nicolai
authors.forename: M
authors.initials: M
authors.lastname: Imbriaco
authors.forename: M L
authors.initials: ML
authors.lastname: Mangoni di Santo Stefano
authors.forename: M
authors.initials: M
authors.lastname: Salvatore
mesh_terms: D003287:Contrast Media; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D005069:Evaluation Studies as Topic; D005080:Exercise Test; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009570:Nitriles; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D017256:Technetium Tc 99m Sestamibi
chemical_list: D003287:Contrast Media; D009570:Nitriles; D015609:Organotechnetium Compounds; D017256:Technetium Tc 99m Sestamibi
vernacular_title: La scintigrafia miocardica con tecnezio 99m metossi-isobutil-isonitrile. Confronto con l'arteriografia coronarica nei pazienti con sospetta cardiopatia ischemica.