Pulsatile secretory patterns of luteinizing hormone in two patients with secondary amenorrhea suffering from Cushing's disease, before and after transsphenoidal adenectomy.
In two infertile women with Cushing's disease, LH pulse frequency increased after pituitary adenectomy; both conceived within 4 months. This finding suggests that defective LH-RH-stimulation of LH secretion accounted (partially) for their infertility.
Hompes
P G
PG
Free University Hospital, Amsterdam, The Netherlands.
Scheele
F
F
Gooren
L J
LJ
Schoemaker
J
J
D000204:Activity Cycles; D000328:Adult; D000568:Amenorrhea / Q000209:etiology / Q000503:physiopathology*; D003480:Cushing Syndrome / Q000097:blood / Q000601:surgery*; D005260:Female; D006801:Humans; D007016:Hypophysectomy; D007247:Infertility, Female / Q000097:blood / Q000209:etiology; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism*
D007986:Luteinizing Hormone