title: Inserting foreign peptides into the major coat protein of bacteriophage M13.
abstract: Foreign DNA fragments were inserted into filamentous phage gene VIII to create hybrid B-proteins with foreign sequences in the amino terminus. The hybrid proteins are incorporated into the virions which retain viability and infectivity. Virions with hybrid B-proteins have the same contour length and the same number of B-protein molecules as virions with natural B-proteins. It was shown that for one of hybrid B-proteins the position of the processing site had changed.
authors.affiliation: Research and Technology Institute of Biologically Active Substances, Vektor NPO, Berdsk, Novosibirsk, Region, USSR.
authors.forename: A A
authors.initials: AA
authors.lastname: Ilyichev
authors.forename: O O
authors.initials: OO
authors.lastname: Minenkova
authors.forename: G P
authors.initials: GP
authors.lastname: Kishchenko
authors.forename: S I
authors.initials: SI
authors.lastname: Tat'kov
authors.forename: N N
authors.initials: NN
authors.lastname: Karpishev
authors.forename: A M
authors.initials: AM
authors.lastname: Eroshkin
authors.forename: V I
authors.initials: VI
authors.lastname: Ofitzerov
authors.forename: Z A
authors.initials: ZA
authors.lastname: Akimenko
authors.forename: V A
authors.initials: VA
authors.lastname: Petrenko
authors.forename: L S
authors.initials: LS
authors.lastname: Sandakhchiev
mesh_terms: D000595:Amino Acid Sequence; D001435:Bacteriophages / Q000235:genetics* / Q000472:pathogenicity; D001483:Base Sequence; D002213:Capsid / Q000235:genetics*; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D010455:Peptides / Q000235:genetics*; D010957:Plasmids
chemical_list: D010455:Peptides