[New paths in the pathogenetic correction of hemic hypoxia].
It is stated that prophylactic administration of ional (dibunol) and taurine to rats exerts an antihypoxic effect in case of acute hemic hypoxia. It is expressed in a decrease of methemoglobin level in blood, increase of pO2, in the skeletal muscles, normalization of the structure of hematoparenchymatous barriers, prevention or decrease in a fall of the rate of oxygen consumption by tissues.
Man'kov'ska
I M
IM
Nazarenko
A I
AI
Nosar
V I
VI
Hovorukha
T M
TM
Sydoriak
N H
NH
D000818:Animals; D002084:Butylated Hydroxytoluene / Q000627:therapeutic use; D004353:Drug Evaluation, Preclinical; D000860:Hypoxia / Q000209:etiology / Q000378:metabolism / Q000517:prevention & control*; D008297:Male; D008706:Methemoglobin / Q000032:analysis; D010101:Oxygen Consumption / Q000187:drug effects; D010313:Partial Pressure; D051381:Rats; D011919:Rats, Inbred Strains; D012977:Sodium Nitrite; D013654:Taurine / Q000627:therapeutic use
D013654:Taurine; D002084:Butylated Hydroxytoluene; D008706:Methemoglobin; D012977:Sodium Nitrite
Novi shliakhy patohenetychnoï korektsiï hemichnoï hipoksiï.