Body composition in growth hormone-deficient adults.
Body composition in a group of growth hormone (GH)-deficient adults was compared with a control group matched for age, sex, body height, body weight, and body mass index by using bioelectrical impedance and deuterium oxide-dilution methods and hydrodensitometry. The body-fat percentages of GH-deficient adults were higher despite comparable weight, height, age, and body mass index. Body impedance was higher in the GH-deficient adults after correction for differences in height and fat-free mass. As a consequence, prediction formulas for body composition from body impedance developed in normal subjects cannot be applied to GH-deficient subjects. The higher body impedance in the GH-deficient subjects can be ascribed to a smaller amount of extracellular water in these subjects than in control subjects.
Binnerts
A
A
Department of Internal Medicine, University Hospital Dijkzigt, Rotterdam, The Netherlands.
Deurenberg
P
P
Swart
G R
GR
Wilson
J H
JH
Lamberts
S W
SW
D000273:Adipose Tissue / Q000473:pathology; D000328:Adult; D001823:Body Composition; D001827:Body Height; D015992:Body Mass Index; D001834:Body Water; D001835:Body Weight; D003397:Craniopharyngioma / Q000473:pathology*; D003720:Densitometry; D005260:Female; D013006:Growth Hormone / Q000172:deficiency*; D006801:Humans; D007018:Hypopituitarism / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis
D013006:Growth Hormone