The effect of sedation with propofol on postoperative bronchoconstriction in patients with hyperreactive airway disease.
Two patients with chronic obstructive pulmonary disease developed postoperatively bronchospasm after insertion of a prostetic aortic valve. Continuous sedation with propofol infusion was associated with a significant decline in peak inspiratory pressure suggesting that propofol may have bronchodilating properties.
Pedersen
C M
CM
Department of Anaesthesiology and Intensive Care, Skejby University Hospital, Aarhus, Denmark.
D000368:Aged; D001024:Aortic Valve Stenosis / Q000150:complications / Q000601:surgery*; D001249:Asthma / Q000150:complications*; D001986:Bronchial Spasm / Q000139:chemically induced* / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D008176:Lung Volume Measurements; D008297:Male; D011183:Postoperative Complications / Q000139:chemically induced* / Q000503:physiopathology / Q000628:therapy; D015742:Propofol / Q000009:adverse effects*; D012121:Respiration, Artificial
D015742:Propofol