title: [Diagnostic and therapeutic strategies in locally recurrent rectal cancer].
abstract: Following curative operation for rectal cancer, 14-44% of the patients develop a local recurrence, in most instances situated in the operative bed. Differentiation of recurrent tumor, scar tissue and inflammation is not always possible by computerized tomography and magnetic resonance imaging. Recurrent tumor in these patients is diagnosed by percutaneous biopsy and histological analysis. In 24 patients in whom operation was impossible and a maximum irradiation dose was also applied, chemotherapy was administered in the form of regional perfusions. The internal iliac arteries were perfused with folinic acid and 5-fluorouracil in these patients. This procedure reduced the intensity of pain or achieved a pain-free interval of 9 days to 8 months.
authors.affiliation: Institut für Strahlendiagnostik der Städtischen Kliniken Dortmund.
authors.forename: K
authors.initials: K
authors.lastname: Mathias
authors.forename: F M
authors.initials: FM
authors.lastname: Hasse
authors.forename: B
authors.initials: B
authors.lastname: Theophil
authors.forename: D
authors.initials: D
authors.lastname: Löhlein
authors.forename: G
authors.initials: G
authors.lastname: Hoffmann
authors.forename: P
authors.initials: P
authors.lastname: Haarmann
authors.forename: D
authors.initials: D
authors.lastname: Lüth
authors.forename: T
authors.initials: T
authors.lastname: Löffler
mesh_terms: D016461:Chemoembolization, Therapeutic; D010478:Chemotherapy, Cancer, Regional Perfusion; D005260:Female; D005860:Germany, West / Q000453:epidemiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy; D012004:Rectal Neoplasms / Q000453:epidemiology / Q000601:surgery*; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
vernacular_title: Diagnostische und therapeutische Strategie beim lokal rezidivierenden Rektumkarzinom.