title: Colloid scintigraphy showing red bone marrow extension in patients with prostatic carcinoma.
abstract: In 25 of 30 patients with bone metastases from prostatic carcinoma, red bone marrow extension was observed by scintigraphy of the reticuloendothelial system (RES). The degree of bone marrow extension in the lower extremities increased with increasing number of bone metastases. In 8 patients, 15 peripheral metastases were detected, all located in areas with extended red bone marrow. The distal level of bone marrow extension coincided with that of the most distal metastases. This is of importance for the detection of peripheral metastases at risk for fracture. Bone marrow extension was also seen in 5 of 8 patients with prostatic carcinoma without bone metastases and was interpreted as a paramalignant activation of RES.
authors.affiliation: Department of Diagnostic Radiology, St. Göran's Hospital, Stockholm, Sweden.
authors.forename: U
authors.initials: U
authors.lastname: Rudberg
authors.forename: R
authors.initials: R
authors.lastname: Udén
authors.forename: S O
authors.initials: SO
authors.lastname: Ahlbäck
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001853:Bone Marrow / Q000000981:diagnostic imaging*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D006801:Humans; D008297:Male; D008875:Middle Aged; D012157:Mononuclear Phagocyte System / Q000000981:diagnostic imaging*; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D013668:Technetium Tc 99m Aggregated Albumin; D013669:Technetium Tc 99m Medronate
chemical_list: D013668:Technetium Tc 99m Aggregated Albumin; D013669:Technetium Tc 99m Medronate