title: Severely reduced recombination in females of the South American marsupial Monodelphis domestica.
abstract: The gray short-tailed opossum, Monodelphis domestica, is a model species for studying the underlying mechanisms that govern recombination. We have identified a new marker, PI (protease inhibitor), in M. domestica and demonstrate its linkage to AK1 (adenylate kinase 1). The rate of recombination in females of this species is approximately one fifth the rate in males, as might be predicted from the difference in chiasma frequency between the two sexes.
authors.affiliation: Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147.
authors.forename: R A
authors.initials: RA
authors.lastname: van Oorschot
authors.forename: P A
authors.initials: PA
authors.lastname: Porter
authors.forename: C M
authors.initials: CM
authors.lastname: Kammerer
authors.forename: J L
authors.initials: JL
authors.lastname: VandeBerg
mesh_terms: D000263:Adenylate Kinase / Q000235:genetics*; D000818:Animals; D005260:Female; D005819:Genetic Markers / Q000235:genetics; D008126:Lod Score; D008297:Male; D009893:Opossums / Q000235:genetics*; D011995:Recombination, Genetic / Q000235:genetics*; D012727:Sex Characteristics; D013020:South America; D000515:alpha 1-Antitrypsin / Q000235:genetics*
chemical_list: D005819:Genetic Markers; D000515:alpha 1-Antitrypsin; D000263:Adenylate Kinase