title: Reticular erythematous mucinosis and acral papulokeratotic lesions associated with myxoedema due to Hashimoto thyroiditis.
abstract: A case is described of a patient with generalized myxoedema due to Hashimoto thyroiditis involving lesions of reticular erythematous mucinosis and acral papulokeratotic lesions with 'church spire' histological pattern. Substitutive treatment with thyroid hormone led to a rapid regression of the cutaneous lesions. The infrequent association of reticular erythematous mucinosis lesions and other forms of cutaneous mucinoses with hypothyroidism is discussed, with special emphasis on the fact that the underlying thyroid disease in all cases was Hashimoto thyroiditis. The association of distal keratotic papules with hypothyroidism has not been previously reported in the literature.
authors.affiliation: Department of Dermatology, General University Hospital, University of Salamanca, Spain.
authors.forename: J A
authors.initials: JA
authors.lastname: Velasco
authors.forename: J C
authors.initials: JC
authors.lastname: Santos
authors.forename: V
authors.initials: V
authors.lastname: Villabona
authors.forename: J
authors.initials: J
authors.lastname: Santana
mesh_terms: D004890:Erythema / Q000150:complications / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000150:complications / Q000209:etiology* / Q000473:pathology; D007642:Keratosis / Q000150:complications / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged; D009077:Mucins / Q000378:metabolism; D009230:Myxedema / Q000150:complications / Q000209:etiology* / Q000473:pathology; D013967:Thyroiditis, Autoimmune / Q000150:complications*
chemical_list: D009077:Mucins