Cheiro-oral syndrome due to lesions in the corona radiata.
OBJECTIVE
We describe three patients with cheiro-oral syndrome caused by a small lesion in the corona radiata confirmed by high-resolution magnetic resonance imaging.


METHODS
Case 1: A 56-year-old hypertensive man who developed hypesthesia and paresthesia in the left perioral area and hand was found to have a small hematoma just lateral to the right internal capsule. Case 2: A 67-year-old man noticed hypesthesia around the left mouth angle and thumb and index finger. Magnetic resonance imaging revealed a lesion in the right corona radiata. Case 3: A 45-year-old hypertensive man developed numbness in his perioral region and left hand that later spread to his shoulder. Magnetic resonance imaging revealed a recent small infarct in the lower lateral aspect of the right corona radiata.


CONCLUSIONS
A small lesion in the corona radiata can cause cheiro-oral syndrome, whose pathogenetic mechanism in such patients may be explained by the somatotopical location or by the differing vulnerability of the neuropils in the corona radiata.
Omae
T
T
Department of Medicine, National Cardiovascular Center, Osaka, Japan.
Tsuchiya
T
T
Yamaguchi
T
T
D000368:Aged; D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging; D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000473:pathology; D006225:Hand; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009055:Mouth; D009422:Nervous System Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology; D012677:Sensation; D013577:Syndrome; D014057:Tomography, X-Ray Computed