title: Renal microangiography and correlated histopathological observation of cows with nephropathy.
abstract: Seven Holstein-Friesian cows showing chronic nephropathy were studied by renal microangiography and its correlated histopathology. In cases of pyelonephritis associated with severe pathological lesions such as thickening of arterial walls, narrowing of the arterial and arteriolar lumen, and interstitial inflammation and abscess formation, patchy loss of the peritubular capillary plexus from the cortex to the medulla was clearly demonstrated by microangiography. Interlobular arteries were tortuous and attenuated or truncated. Opacification in the vasa rectae and interstitial capillaries was increased. Extensive non-perfused regions could be detected in the cortex. In cases of mild interstitial nephritis and moderate pyelonephritis, microangiography showed focal changes in the renal vasculature. Microangiography is thus shown to clearly demonstrate changes in the renal vasculature corresponding to the severity of the histopathological lesions.
authors.affiliation: Department of Hygiene, Hamamatsu University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Sugimoto
authors.forename: N
authors.initials: N
authors.lastname: Sakurai
authors.forename: M
authors.initials: M
authors.lastname: Kaneko
authors.forename: H
authors.initials: H
authors.lastname: Shirasawa
authors.forename: K
authors.initials: K
authors.lastname: Shibata
authors.forename: M
authors.initials: M
authors.lastname: Miyata
authors.forename: T
authors.initials: T
authors.lastname: Noguchi
authors.forename: K
authors.initials: K
authors.lastname: Uematsu
authors.forename: K
authors.initials: K
authors.lastname: Shimoda
authors.forename: J
authors.initials: J
authors.lastname: Sakata
mesh_terms: D000792:Angiography / Q000662:veterinary; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D007668:Kidney / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000473:pathology; D007674:Kidney Diseases / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary*; D008833:Microcirculation / Q000000981:diagnostic imaging; D009395:Nephritis, Interstitial / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary; D011704:Pyelonephritis / Q000000981:diagnostic imaging / Q000473:pathology / Q000662:veterinary