Sex but no hand difference in the isthmus of the corpus callosum.
We performed high-resolution magnetic resonance morphometry of the total midsagittal area and seven midsagittal subareas of the corpus callosum in healthy young adult dextrals and sinistrals (N = 52). There was no influence of handedness on these anatomic measurements. However, an effect of sex emerged, with women (N = 26) having a larger proportional isthmus segment of the callosum. This may reflect a sex-specific difference in the interhemispheric connectivity and functional organization of the temporoparietal association cortex.
Steinmetz
H
H
Department of Neurology, Heinrich-Heine University, Düsseldorf, Germany.
Jäncke
L
L
Kleinschmidt
A
A
Schlaug
G
G
Volkmann
J
J
Huang
Y
Y
D000328:Adult; D000704:Analysis of Variance; D003337:Corpus Callosum / Q000033:anatomy & histology / Q000502:physiology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D015999:Multivariate Analysis; D012727:Sex Characteristics