[Diagnostic significance of osteocalcin levels in the classification of senile osteoporosis].
The authors investigated the osteocalcin (BGP) serum level in 55 women with the senile type of osteoporosis. According to BGP values they divided the group into three sub-groups. Lower values were recorded in 27 subjects (50%), normal values comparable with a control group of 13 healthy women of equal age were recorded in 21 subjects (38%) and in a small sub-group of 7 women (12%) the BGP level was raised or high. Senile osteoporosis can be also heterogeneous, characterized by a reduced, normal but in some also an elevated metabolic turnover of bone. It is, however, possible that this is a question of different stages and at the time of examination the mentioned status was recorded. An opportunity to examine BGP levels would be a great asset for osteological departments, among others also for the classification of osteoporosis with regard to the rate of the metabolic turnover or remodelling activity and would provide doctors with valuable information for decision taking on rational therapy.
Neradilová
M
M
Endokrinologický ústav, Praha.
Soutorová
M
M
Bednár
J
J
Simecková
A
A
D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008875:Middle Aged; D015675:Osteocalcin / Q000097:blood*; D010024:Osteoporosis / Q000097:blood / Q000145:classification*
D015675:Osteocalcin
Diagnostický význam hladiny osteokalcinu pri klasifikaci starecké osteoporózy.