title: Complications of Lyme borreliosis.
abstract: Lyme borreliosis is the multisystem infectious disease caused by the spirochete Borrelia burgdorferi. Complications of this infection can involve many organ systems, especially the skin, joints, nervous system, and heart. These manifestations may be acute, or evolve slowly over months or years. Diagnosis is not always straightforward, and is currently hampered by lack of a specific serologic assay. This review discusses the syndromes associated with Lyme borreliosis and addresses issues of diagnosis and treatment.
authors.affiliation: Guthrie Foundation for Medical Research, Sayre, Pennsylvania 18840.
authors.forename: W D
authors.initials: WD
authors.lastname: Cooke
authors.forename: R J
authors.initials: RJ
authors.lastname: Dattwyler
mesh_terms: D000907:Antibodies, Bacterial / Q000032:analysis; D001170:Arthritis, Infectious / Q000175:diagnosis / Q000276:immunology; D015748:Borrelia burgdorferi Group / Q000276:immunology; D015787:Erythema Chronicum Migrans / Q000175:diagnosis / Q000276:immunology; D005260:Female; D006327:Heart Block / Q000175:diagnosis / Q000276:immunology; D006801:Humans; D008193:Lyme Disease / Q000175:diagnosis* / Q000276:immunology; D009422:Nervous System Diseases / Q000175:diagnosis / Q000276:immunology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial