Drug-induced hypokalaemia. A cause for concern.
Drug-induced hypokalaemia is a widespread problem in the elderly that can be caused by many therapeutically useful substances, the most common of which are diuretics. In certain classes of patients (e.g. those with acute myocardial infarction, with congestive heart failure receiving digitalis, or with cirrhosis), iatrogenic hypokalaemia is an established risk factor. In patients with hypertension who have no underlying heart disease or liver disease, the use of diuretics may lead to worsened glucose tolerance and cardiac arrhythmias. There is also evidence for an increased risk of sudden cardiac death.
Isaac
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Department of Internal Medicine, University of Texas Medical Branch, Galveston.
Holland
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D000368:Aged; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D000970:Antineoplastic Agents / Q000009:adverse effects; D003287:Contrast Media / Q000009:adverse effects; D004232:Diuretics / Q000009:adverse effects; D005938:Glucocorticoids / Q000009:adverse effects; D006801:Humans; D007008:Hypokalemia / Q000139:chemically induced* / Q000150:complications / Q000517:prevention & control; D013566:Sympathomimetics / Q000009:adverse effects; D014805:Vitamin B 12 / Q000009:adverse effects
D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D003287:Contrast Media; D004232:Diuretics; D005938:Glucocorticoids; D013566:Sympathomimetics; D014805:Vitamin B 12