title: Verapamil and valproic acid treatment of prolonged mania.
abstract: The case of an adolescent with severe mental retardation, blindness, and a complex of behavioral symptoms consistent with mania is reported. Symptoms include an increased activity level, mood liability, irritability, hyposomia, and severe self-injurious behavior. The successful use of verapamil and valproic acid in the treatment of prolonged mania in this child is described.
authors.affiliation: Columbia University College of Physicians and Surgeons.
authors.forename: T
authors.initials: T
authors.lastname: Kastner
authors.forename: D L
authors.initials: DL
authors.lastname: Friedman
mesh_terms: D000293:Adolescent; D001143:Arousal / Q000187:drug effects; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000523:psychology; D004359:Drug Therapy, Combination; D006801:Humans; D008607:Intellectual Disability / Q000188:drug therapy*; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D019965:Neurocognitive Disorders / Q000188:drug therapy / Q000523:psychology; D014635:Valproic Acid / Q000008:administration & dosage*; D014700:Verapamil / Q000008:administration & dosage*
chemical_list: D014635:Valproic Acid; D014700:Verapamil