Morphea with high titer of fibronectin antibodies.
A 20-year-old man with a 9-year history of unusual subcutaneous morphea with nodular lesions in a circular arrangement and wooden-hard symmetrical induration of the arms, had high titers of fibronectin antibodies. A possible role of fibronectin and antifibronectin antibodies in the pathogenesis of scleroderma is discussed.
Stefanato
C M
CM
Department of Dermatology, Warsaw Academy of Medicine, Poland.
Gorkiewicz-Petkow
A
A
Jarzabek-Chorzelska
M
M
Jablonska
S
S
Chorzelski
T
T
D000328:Adult; D000906:Antibodies / Q000032:analysis*; D005353:Fibronectins / Q000276:immunology*; D005455:Fluorescent Antibody Technique; D006801:Humans; D008297:Male; D012594:Scleroderma, Localized / Q000276:immunology* / Q000473:pathology
D000906:Antibodies; D005353:Fibronectins