title: [The mercury exposure of the population. III. Mercury mobilisation by DMPS (Dimaval) in subjects with and without amalgam fillings].
abstract: The urinary excretion of mercury (per 24 h) was determined in 29 subjects before and after application of DMPS (2.3-dimercapto-1-propane sulfonic acid, 300 mg per os). A 6-7 fold increase of mercury excretion was noted after application of DMPS. Subjects with amalgam fillings excreted significantly more mercury before as well as after application of DMPS than subjects without amalgam fillings. Urinary mercury excretion was significantly correlated with the number of amalgam fillings. About 50% of the variance of urinary mercury can be explained by the number of amalgam fillings. The results show that the release of mercury from amalgam fillings represents the main source of mercury exposure in subjects with amalgam fillings.
authors.affiliation: Medizinischen Institut für Umwelthygiene, Heinrich-Heine-Universität Düsseldorf.
authors.forename: D
authors.initials: D
authors.lastname: Zander
authors.forename: U
authors.initials: U
authors.lastname: Ewers
authors.forename: I
authors.initials: I
authors.lastname: Freier
authors.forename: A
authors.initials: A
authors.lastname: Brockhaus
mesh_terms: D000328:Adult; D003723:Dental Amalgam / Q000493:pharmacokinetics*; D003793:Dental Restoration, Permanent; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008297:Male; D008628:Mercury / Q000652:urine*; D008875:Middle Aged; D014494:Unithiol / Q000493:pharmacokinetics*
chemical_list: D014494:Unithiol; D003723:Dental Amalgam; D008628:Mercury
vernacular_title: Untersuchungen zur Quecksilberbelastung der Bevölkerung. III. Quecksilbermobilisation durch DMPS (Dimaval) bei Personen mit und ohne Amalgamfüllungen.