Gallium-67-labelled red blood cells as a blood-pool marker for dual-isotope imaging.
Red blood cells were labelled with 67Ga oxine prepared from 67Ga citrate, a routinely available and relatively inexpensive radiopharmaceutical which is suitable for dual-isotope imaging with 99mTc. Labelling efficiency was 88 +/- 1%, 24-h in vitro stability was 93 +/- 5% in saline at room temperature and 68 +/- 4% in whole blood at 37 degrees C, and the method could be performed within 20-30 min.
Ballinger
J R
JR
Department of Nuclear Medicine, Princess Margaret Hospital, Toronto, Ontario, Canada.
Boxen
I
I
D004912:Erythrocytes / Q000378:metabolism*; D005710:Gallium Radioisotopes; D006801:Humans; D015125:Oxyquinoline / Q000737:chemistry; D011725:Pyridines / Q000737:chemistry; D013871:Thiones; D014334:Tropolone / Q000097:blood / Q000378:metabolism
D005710:Gallium Radioisotopes; D011725:Pyridines; D013871:Thiones; D015125:Oxyquinoline; C008704:pyrithione; D014334:Tropolone