[Urinary tract infections caused by Staphylococcus saprophyticus. Increased incidence depending on the blood group].
Between 1. 1. 1988 and 31. 12. 1990, greater than or equal to 10 colony-forming units of Staph. saprophyticus were isolated from 55 of a total of 20,000 urine samples went in. The isolates from these 55 patients (52 women, 3 men; mean age 29 [17-58] years) were tested for specific adhesion molecules (lectins) to discover their relationship to blood-group characteristic carbohydrates. 52 of the 55 patients (94.5%) were blood-group A or AB (average for Middle-Europeans: 48.2%). Haemagglutination and inhibition tests with the Staph. saprophyticus isolates demonstrated in all instances N-acetylgalactosamine (GalNAc) specificity of the surface lectins. These findings support the hypothesis that the carbohydrate pattern of Blood group A (terminal GalNAc) is important for the colonization of exposed organs by Staph. saprophyticus with GalNAc-specific lectins.
Beuth
J
J
Institut für Medizinische Mikrobiologie und Hygiene, Universität Köln.
Ko
H L
HL
Tunggal
L
L
Pulverer
G
G
D000017:ABO Blood-Group System; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D015331:Cohort Studies; D005260:Female; D006385:Hemagglutination Inhibition Tests; D006386:Hemagglutination Tests; D006801:Humans; D037102:Lectins / Q000032:analysis; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology*; D013210:Staphylococcus / Q000276:immunology / Q000302:isolation & purification; D014552:Urinary Tract Infections / Q000453:epidemiology / Q000382:microbiology*
D000017:ABO Blood-Group System; D037102:Lectins
Harnwegsinfektionen durch Staphylococcus saprophyticus. Gehäuftes Auftreten in Abhängigkeit von der Blutgruppe.