Sperm chromosome analysis of a man heterozygous for a pericentric inversion of chromosome 20.
The sperm chromosomes of a man heterozygous for inv(20)(p13q11.2) were analyzed. Twenty-six sperm chromosome complements were examined, of which fourteen contained the normal chromosome, and twelve the inverted chromosome. None of the sperm complements contained a recombinant chromosome 20. The frequency of structural chromosomal aberrations unrelated to the inversion was 11.5% (3/26). Numerical aberrations were not observed. The percentages of X- and Y-bearing sperm were 56% and 44%, respectively, which was similar to the expected 1:1 ratio.
Jenderny
J
J
Institut für Humangenetik und Anthropologie der Universität, Düsseldorf, Federal Republic of Germany.
Gebauer
J
J
Röhrborn
G
G
Rüger
A
A
D007446:Chromosome Inversion; D002890:Chromosomes, Human, Pair 20; D006579:Heterozygote; D006801:Humans; D008297:Male; D013094:Spermatozoa / Q000648:ultrastructure*; D014960:X Chromosome; D014998:Y Chromosome