title: Transdermal fentanyl in cancer pain.
abstract: Transdermal fentanyl appears to be a safe and practical alternative to short-acting analgesics in the treatment of cancer pain. The unique pharmacokinetics of the transdermal system, including the prolonged time to peak analgesic effect, long elimination half-life and skin depot concept, should be kept in mind when prescribing the system. Short-acting narcotics are recommended for break-through pain. Side effects of fentanyl, and their management, are similar to those associated with other narcotic analgesics.
authors.affiliation: York Hospital, Pennsylvania.
authors.forename: K H
authors.initials: KH
authors.lastname: Mosser
mesh_terms: D000279:Administration, Cutaneous; D005283:Fentanyl / Q000008:administration & dosage* / Q000009:adverse effects / Q000191:economics / Q000493:pharmacokinetics; D006801:Humans; D009369:Neoplasms / Q000150:complications*; D010146:Pain / Q000188:drug therapy*
chemical_list: D005283:Fentanyl