Molecular diagnosis of Ureaplasma urealyticum septic arthritis in a patient with hypogammaglobulinemia.
OBJECTIVE
We report a hypogammaglobulinemic patient with a destructive oligoarticular arthritis, whose synovial fluid cultures were repeatedly sterile.


RESULTS
We identified a Ureaplasma urealyticum infection in his affected joints, using a polymerase chain reaction (PCR) assay.


CONCLUSIONS
The PCR technique promises to be extremely valuable in the rapid and specific diagnosis of infectious arthritis.
Lee
A H
AH
Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia.
Ramanujam
T
T
Ware
P
P
Edelstein
P H
PH
Brooks
J J
JJ
Freundlich
B
B
Schumacher
H R
HR
Zurier
R B
RB
Weiner
D B
DB
Williams
W V
WV
D000328:Adult; D000361:Agammaglobulinemia / Q000150:complications*; D001170:Arthritis, Infectious / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism; D001483:Base Sequence; D004269:DNA, Bacterial / Q000032:analysis*; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011948:Receptors, Antigen, T-Cell / Q000235:genetics / Q000378:metabolism; D013583:Synovial Membrane / Q000378:metabolism; D016869:Ureaplasma Infections / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism; D016990:Ureaplasma urealyticum / Q000235:genetics
D004269:DNA, Bacterial; D011948:Receptors, Antigen, T-Cell