The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach.
Partial sequences corresponding to eleven novel Rab proteins and one new Rho protein have been isolated using a PCR-based cloning approach. These results confirm that the overall diversity of the Rab and Rho protein subfamilies account for more than thirty different members in mammalian cells.
Chavrier
P
P
Cell Biology Programme, European Molecular Biology Laboratory, Heidelberg, F.R.G.
Simons
K
K
Zerial
M
M
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015152:Blotting, Northern; D003001:Cloning, Molecular / Q000379:methods*; D019204:GTP-Binding Proteins / Q000737:chemistry / Q000235:genetics*; D051379:Mice; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction
D019204:GTP-Binding Proteins