Nucleotide sequence of the ospAB operon of a Borrelia burgdorferi strain expressing OspA but not OspB.
The nucleotide sequence of a 1.6-kb clone containing the gene for outer surface protein A (OspA) of a German strain (GO2) of Borrelia burgdorferi was determined. The deduced amino acid sequence showed a homology of 82% to the OspA molecules from three other B. burgdorferi strains. The best-conserved region was recognized at the 36-amino-terminal amino acids of OspA. OspB could not be identified in the strain investigated, probably because the nucleotide sequence of the ospAB operon prevented expression of the OspB gene.
Eiffert
H
H
Department of Medical Microbiology, University of Göttingen, Germany.
Ohlenbusch
A
A
Fehling
W
W
Lotter
H
H
Thomssen
R
R
D000595:Amino Acid Sequence; D000818:Animals; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D001483:Base Sequence; D015748:Borrelia burgdorferi Group / Q000235:genetics*; D003001:Cloning, Molecular; D008969:Molecular Sequence Data; D009876:Operon; D011817:Rabbits
D001425:Bacterial Outer Membrane Proteins