Stimulation of granulopoiesis in pregnant swine and their offspring by Propionibacterium avidum KP-40.
Functional parameters of granulopoiesis were measured in gilts, in pregnant sows and in their offspring. Groups of dams and piglets were injected with a potent immunomodulator--killed lyophilized Propionibacterium avidum KP-40 (PA). Administration of PA (0.1 mg/kg body wt for sows and 0.2 mg/kg body wt for piglets) resulted in significant stimulation of all measured parameters of granulopoiesis as well as in a faster gain of body weight. PA stimulation of sows prior to farrowing had no measurable influence on the development of their offspring.
Markowska-Daniel
I
I
Department of Swine Diseases, Veterinary Research Institute, Pulawy, Poland.
Pejsak
Z
Z
Szmigielski
S
S
Jeljaszewicz
J
J
Pulverer
G
G
D000276:Adjuvants, Immunologic; D000818:Animals; D005260:Female; D006098:Granulocytes; D006410:Hematopoiesis; D011247:Pregnancy; D011424:Propionibacterium / Q000276:immunology*; D011897:Random Allocation; D013552:Swine / Q000276:immunology*
D000276:Adjuvants, Immunologic