Circadian and menstrual rhythms in frequency variations of spontaneous otoacoustic emissions from human ears.
This paper reports hourly and daily monitoring of the frequencies of spontaneous otoacoustic emissions. Regular circadian variations in frequency were found in two of three subjects. Consistent monthly variations, in step with the menstrual cycle, were seen in three of four women. The circadian cycle typically showed a rise in frequency of 0.6-1% while asleep and a similar fall while awake. The monthly cycle typically saw frequencies rise and fall by 0.4-0.6%, reaching a minimum near the onset of menstruation, and rising to a peak close to ovulation. A review of the literature revealed that certain cardiovascular parameters such as arterial blood pressure follow, over both daily and menstrual cycles, a broadly similar time course to SOAE frequency. Further experiments produced data supporting a relationship between blood pressure and SOAE frequency, and it is therefore suggested that much of the circadian-linked, menstrual-linked, and background variation in SOAE frequency may arise from cardiovascular changes. A likely causal mechanism, involving cerebrospinal fluid, is discussed.
Bell
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Research School of Biological Sciences, Australian National University, Canberra.
D000162:Acoustics; D000328:Adult; D001794:Blood Pressure / Q000502:physiology; D015170:Cerebrospinal Fluid Pressure / Q000502:physiology; D002940:Circadian Rhythm / Q000502:physiology*; D003052:Cochlear Aqueduct / Q000502:physiology; D004423:Ear / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008597:Menstrual Cycle / Q000502:physiology*; D010498:Perilymph / Q000502:physiology; D011312:Pressure