title: [Azosemide--a loop diuretic with protracted effect].
abstract: Azosemide, a novel loop diuretic that has been available for the past few years, acts qualitatively like thiazide, viz by prolonging the diuretic effect with, however, only a slight delay in the onset of diuresis, in combination with the quantitative effect of previous loop diuretics, i.e. large excretion volumes. On the basis of experience gained to date, specific indications will presumably be cardiac and renal edema and ascites, also as long-term treatment. Provided that no NaCl or volume deficiency presents, side effects are insignificant.
authors.forename: D
authors.initials: D
authors.lastname: Michel
mesh_terms: D004232:Diuretics / Q000627:therapeutic use*; D004487:Edema / Q000097:blood / Q000188:drug therapy*; D006801:Humans; D008138:Loop of Henle / Q000187:drug effects; D008657:Metabolic Clearance Rate; D013424:Sulfanilamides / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D013777:Tetrazoles; D013876:Thiophenes; D000096926:Benzenesulfonamides
chemical_list: D004232:Diuretics; D013424:Sulfanilamides; C018222:azosemide; D013777:Tetrazoles; D013876:Thiophenes; D000096926:Benzenesulfonamides
vernacular_title: Azosemid--ein Schleifendiuretikum mit protrahierter Wirkung.