Beneficial effects of silicone cream on grafted skin.
The clinical effects of silicone cream were compared to vaseline on 27 patients with split (14 cases) and full thickness (13) skin grafts. Silicone cream occlusive treatment resulted in significantly less pigmentation and hardness in 21 out of 27 cases (78%), less marginal scar hypertrophy and redness in 10 and 7 cases respectively (37 and 26%), and in an even narrower marginal scar in 6 cases (22%). In nine cases of the split skin graft, fewer wrinkles resulted in the silicone cream treated lesion.
Sawada
Y
Y
Department of Plastic and Reconstructive Surgery, Hirosaki University School of Medicine, Japan.
Sone
K
K
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D002921:Cicatrix / Q000473:pathology*; D005260:Female; D006801:Humans; D006984:Hypertrophy / Q000517:prevention & control; D007223:Infant; D008297:Male; D008875:Middle Aged; D009779:Occlusive Dressings; D010577:Petrolatum / Q000627:therapeutic use; D011183:Postoperative Complications / Q000517:prevention & control; D012827:Silicone Oils / Q000627:therapeutic use*; D016038:Skin Transplantation; D014945:Wound Healing / Q000187:drug effects
D012827:Silicone Oils; D010577:Petrolatum