title: Clinical applications of gonadotropin-releasing hormones in reproductive disorders.
abstract: Gonadotropin-releasing hormone (GnRH) agonists show promise as new therapeutic agents with considerable potential for clinical applications in endocrinology, gynecology, pediatrics, and oncology. GnRH agonists are derived from GnRH. This article reviews the physiology and neuroendocrine effects of GnRH and discusses clinical applications of the native substance and its analogs.
authors.affiliation: Department of Obstetrics and Gynecology, Wayne State University, Detroit, Michigan.
authors.forename: K S
authors.initials: KS
authors.lastname: Moghissi
mesh_terms: D004700:Endocrine System Diseases / Q000188:drug therapy*; D004715:Endometriosis / Q000188:drug therapy; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives / Q000502:physiology*; D006066:Gonads; D006628:Hirsutism / Q000188:drug therapy; D006801:Humans; D007889:Leiomyoma / Q000188:drug therapy; D008297:Male; D009376:Neoplasms, Hormone-Dependent / Q000188:drug therapy; D010062:Ovulation Induction; D011628:Puberty, Delayed / Q000188:drug therapy; D011629:Puberty, Precocious / Q000188:drug therapy; D014594:Uterine Neoplasms / Q000188:drug therapy
chemical_list: D007987:Gonadotropin-Releasing Hormone