[The current status of the problem of the biological indication of radiation lesions].
Current information is presented in the paper concerning the biological indication of radiation effects within a wide range of doses. The radiobiological phenomena that lay the basis for the development of methods of diagnosis of radiation injury are discussed. Basic requirements to biological indicators and principles of elaboration of the system of laboratory diagnosis of radiation injury are reported. A new classification of biological indicators of radiation affection based on the principles of pathogenesis is proposed. The informativeness of the diagnosis methods available is evaluated and the directions, which the search for new biological indications of radiation effect should follow, are outlined.
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D015415:Biomarkers / Q000737:chemistry; D001704:Biopolymers; D004249:DNA Damage; D004307:Dose-Response Relationship, Radiation; D015894:Genome, Human; D006801:Humans; D008722:Methods; D009154:Mutation / Q000528:radiation effects; D011832:Radiation Injuries / Q000145:classification / Q000175:diagnosis* / Q000235:genetics
D015415:Biomarkers; D001704:Biopolymers
Sovremennoe sostoianie problemy biologicheskoĭ indikatsii luchevykh porazheniĭ.