Rapid differentiation of Mycobacterium xenopi from mycobacteria of the Mycobacterium avium-intracellulare complex by pyrolysis mass spectrometry.
Thirty four cultures of slow growing, Tween-80 negative mycobacteria were analysed by pyrolysis mass spectrometry. The results showed that pyrolysis mass spectrometry could positively distinguish strains of Mycobacterium xenopi from those of the Mycobacterium avium-intracellulare (MAI) complex. Pyrolysis mass spectrometry may be a useful technique for the rapid characterisation of non-tuberculous mycobacteria in such clinical settings as their isolation from immunocompromised patients-for example, those with AIDS.
Sisson
P R
PR
Regional Public Health Laboratory, General Hospital, Newcastle upon Tyne.
Freeman
R
R
Magee
J G
JG
Lightfoot
N F
NF
D006358:Hot Temperature; D013058:Mass Spectrometry / Q000379:methods; D015269:Mycobacterium avium Complex / Q000145:classification; D009170:Nontuberculous Mycobacteria / Q000145:classification*