title: Ocular invasion in mucormycosis.
abstract: The histopathologic findings in a case of ocular invasion in rhinocerebral mucormycosis are described. The findings of hyphae in the inner sclera and marked involvement of the posterior ciliary arteries suggested an arterial route of ocular invasion by fungus. Only five other cases of rhinocerebral mucormycosis with ocular fungal invasion have been reported to our knowledge. All six patients died from the infection. As a group, these cases suggest that the presence of ocular infiltration by fungus may indicate poor prognosis in rhinocerebral mucormycosis.
authors.affiliation: Department of Ophthalmology, Milton S. Hershey Medical Center, Penn State University, Hershey.
authors.forename: T A
authors.initials: TA
authors.lastname: Sponsler
authors.forename: J W
authors.initials: JW
authors.lastname: Sassani
authors.forename: L N
authors.initials: LN
authors.lastname: Johnson
authors.forename: J
authors.initials: J
authors.lastname: Towfighi
mesh_terms: D000785:Aneurysm, Infected / Q000473:pathology; D001927:Brain Diseases / Q000382:microbiology; D002924:Ciliary Body / Q000098:blood supply; D015821:Eye Infections, Fungal / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009090:Mucorales / Q000302:isolation & purification; D009091:Mucormycosis / Q000473:pathology*; D009668:Nose Diseases / Q000382:microbiology; D011379:Prognosis; D012590:Sclera / Q000382:microbiology