title: Position of double bond of trans isomers of linoleic acid affects fatty acid desaturation and elongation.
abstract: The position of the trans double bond of linoleic acid isomers affects the incorporation of the isomers in tissue lipids and their metabolic conversion to other metabolites. The 9 trans, 12 cis isomer of linoleic acid is a poor substrate and the 9 cis, 12 trans isomer is a good substrate for the enzyme that desaturates dienoic acids at position six.
mesh_terms: D000818:Animals; D004042:Dietary Fats, Unsaturated / Q000378:metabolism*; D005227:Fatty Acids / Q000737:chemistry / Q000378:metabolism*; D007536:Isomerism; D019787:Linoleic Acid; D008041:Linoleic Acids / Q000737:chemistry* / Q000378:metabolism; D050356:Lipid Metabolism; D008968:Molecular Conformation
chemical_list: D004042:Dietary Fats, Unsaturated; D005227:Fatty Acids; D008041:Linoleic Acids; D019787:Linoleic Acid