title: Hemodynamic assessment of vascular malformations by angio CT with generation of functional transit time images.
abstract: We performed a CT dynamic study during the first pass of an intravenously injected bolus of a iodinated contrast medium, followed by generation of the regional arm-brain circulation time (rABCT) image, in 11 patients with vascular malformations. All lesions could be detected as changes of rABCT, and the comparison with values of normal arteries and veins allowed the deduction of the hemodynamic conditions of the lesions. Seven cases showed evidence of altered distribution of rABCT in the corresponding brain hemisphere, suggesting a perfusion reserve impairment.
authors.affiliation: Institute of Clinical Neurology, University of Genoa, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Bartolini
authors.forename: B
authors.initials: B
authors.lastname: Gasparetto
authors.forename: G
authors.initials: G
authors.lastname: Ajmar
authors.forename: R
authors.initials: R
authors.lastname: Amore
authors.forename: M
authors.initials: M
authors.lastname: Furlan
mesh_terms: D000792:Angiography / Q000379:methods*; D001164:Arteriovenous Fistula / Q000000981:diagnostic imaging; D001165:Arteriovenous Malformations / Q000000981:diagnostic imaging*; D001932:Brain Neoplasms / Q000000981:diagnostic imaging; D002340:Carotid Artery Diseases / Q000000981:diagnostic imaging; D002426:Cavernous Sinus / Q000000981:diagnostic imaging; D003626:Data Display; D006391:Hemangioma / Q000000981:diagnostic imaging; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging*; D007472:Iohexol; D011856:Radiographic Image Enhancement; D013382:Subtraction Technique; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D007472:Iohexol