Frontal, temporal, and striatal proton relaxation times in schizophrenic patients and normal comparison subjects.
Spin-lattice (T1) and spin-spin (T2) magnetic resonance relaxation times were examined in frontal, temporal, and striatal regions of 24 patients with schizophrenia and 10 normal comparison subjects. The schizophrenic patients had more prolonged T2 values than did the comparison subjects, particularly in the left temporal cortex and white matter, suggesting tissue pathology.
Williamson
P
P
Department of Psychiatry, University of Western Ontario, London, Canada.
Pelz
D
D
Merskey
H
H
Morrison
S
S
Karlik
S
S
Drost
D
D
Carr
T
T
Conlon
P
P
D000328:Adult; D001479:Basal Ganglia / Q000473:pathology; D003342:Corpus Striatum / Q000473:pathology*; D005260:Female; D005625:Frontal Lobe / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000175:diagnosis* / Q000473:pathology; D013702:Temporal Lobe / Q000473:pathology*