Gastrointestinal involvement in L-tryptophan (L-Trp) associated eosinophilia-myalgia syndrome (EMS).
We report a 45-year-old female who had symptomatic gastrointestinal involvement, eosinophils in the cellular infiltrate, and who proved to have L-tryptophan-associated eosinophilia-myalgia syndrome. This case illustrates that gastrointestinal disease can be a major, seemingly primary clinical presentation in this syndrome, and that a drug history, specifically L-tryptophan, needs to be included in the differential diagnosis of "eosinophilic gastroenteritis."
De Schryver-Kecskemeti
K
K
Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Bennert
K W
KW
Cooper
G S
GS
Yang
P
P
D001706:Biopsy; D002908:Chronic Disease; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology; D004064:Digestive System / Q000473:pathology; D016603:Eosinophilia-Myalgia Syndrome / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D005260:Female; D005767:Gastrointestinal Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D014364:Tryptophan / Q000009:adverse effects*; D015431:Weight Loss / Q000187:drug effects
D014364:Tryptophan