[Fibrosing pneumopathy induced by cyclothiazide. Apropos of a case].
A diffuse interstitial pulmonary fibrosis associated with an idiopathic hepatic cirrhosis occurred in a 79 years old man treated during five years with cyclothiazide and triamterene for a mild systemic hypertension. The outcome was fatal. A provocation test was positive with BAL lymphocytic reaction. Cyclothiazide induced fibrosis is likely.
Kheir
A
A
Service des Maladies Respiratoires et Réanimation Respiratoire, CHRU de Nancy-Brabois.
Chabot
F
F
Lesur
O
O
Gerard
H
H
Delorme
N
N
Polu
J M
JM
D000368:Aged; D000959:Antihypertensive Agents / Q000009:adverse effects*; D001581:Benzothiadiazines / Q000009:adverse effects*; D001992:Bronchoalveolar Lavage Fluid / Q000473:pathology; D004232:Diuretics / Q000009:adverse effects*; D004338:Drug Combinations; D004804:Eosinophils / Q000473:pathology; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D011658:Pulmonary Fibrosis / Q000139:chemically induced* / Q000473:pathology; D014223:Triamterene / Q000009:adverse effects*
D000959:Antihypertensive Agents; D001581:Benzothiadiazines; D004232:Diuretics; D004338:Drug Combinations; C035057:cyclothiazide, triamterene drug combination; C004639:cyclothiazide; D014223:Triamterene
Pneumopathie fibrosante induite par le cyclothiazide. A propos d'un cas.