Transferrin subtypes in 11 south China minority populations.
Transferrin subtypes were determined by isoelectric focussing (IEF) in a total of 2,121 individuals from 11 South China minority populations. The C1, C2 and DCHI alleles were present in all the populations; B alleles were lacking, C4 was found in 3 populations and C3 in 6. C2 and C4 allele frequencies are notable in these minority groups. The frequency of the C2 allele was higher (0.25-0.38) than that of Han Chinese (0.18-0.25). In Bai the C2 frequency was as high as 0.38. The C4 allele was present at a low frequency (less than 0.01), which suggests that this allele probably existed in the ancestral Mongoloid population at a low frequency and increased in frequency in Amerindians due to genetic drift or other factors.
Chen
J X
JX
Laboratory of Blood Typing and Serology, Chinese Academy of Medical Sciences, Chengdu.
Chen
Q
Q
Xu
J J
JJ
Du
R F
RF
D000483:Alleles; D002681:China; D005787:Gene Frequency / Q000235:genetics; D005828:Genetics, Population; D006801:Humans; D008913:Minority Groups; D010641:Phenotype; D014168:Transferrin / Q000235:genetics*
D014168:Transferrin