Raised intracranial pressure and visual complications in AIDS patients with cryptococcal meningitis.
The clinical course of cryptococcal meningitis in AIDS shows some important differences from the features of the illness in non-AIDS patients. Complications such as raised intracranial pressure and visual impairment that are recognised in non-AIDS patients may be less frequent in those with AIDS. Persistent intracranial hypertension should be managed actively to prevent visual impairment. In AIDS patients, in whom ventriculo-peritoneal shunts carry additional risks, acetazolamide can be used successfully to lower the CSF pressure and prevent visual loss.
Johnston
S R
SR
Infectious Diseases Unit, Royal Postgraduate Medical School, Hammersmith Hospital, London, U.K.
Corbett
E L
EL
Foster
O
O
Ash
S
S
Cohen
J
J
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D001766:Blindness / Q000209:etiology; D003389:Cranial Nerve Diseases / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D003455:Cryptococcus neoformans; D005260:Female; D005437:Flucytosine / Q000627:therapeutic use; D006801:Humans; D007427:Intracranial Pressure; D008297:Male; D016919:Meningitis, Cryptococcal / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D008875:Middle Aged; D010211:Papilledema / Q000150:complications; D014454:Uganda / Q000208:ethnology
D000666:Amphotericin B; D005437:Flucytosine