title: [Pressure of the anal canal in patients with hemorrhoids or with anal fissure. Effect of the topical application of an anesthetic gel].
abstract: The pressure measurements and clinical sensation of 11 patients with hemorrhoids and 8 patients with posterior and fissure were analyzed before and after the topical administration of an anesthetic gel containing tetracaine in the anal canal. A significant increase of the maximal basal pressure (p less than 0.01) was observed in comparison with a control group of the same age and sex. No differences in the maximal pressure of voluntary contractions. The anesthetic gel produced a significant decrease of the maximal basal pressure in subjects with hemorrhoids, as well as a lessening of pain in 37% of patients with anal fissure and in 55% of those with hemorrhoids. This symptomatic improvement was not correlated with changes in pressure. Therefore we conclude that the hypertonicity of the anal canal is not secondary to pain and must be evaluated as a disturbance related to the subjacent lesion.
authors.affiliation: Unidad de Motilidad Digestiva, Hospital Clínico Universitario, Valencia.
authors.forename: M
authors.initials: M
authors.lastname: Mínguez
authors.forename: M
authors.initials: M
authors.lastname: Tomás-Ridocci
authors.forename: A
authors.initials: A
authors.lastname: García
authors.forename: A
authors.initials: A
authors.lastname: Benages
mesh_terms: D000287:Administration, Topical; D000328:Adult; D001003:Anal Canal / Q000187:drug effects* / Q000503:physiopathology*; D005260:Female; D005401:Fissure in Ano / Q000503:physiopathology*; D005782:Gels; D006484:Hemorrhoids / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D011312:Pressure; D012677:Sensation; D013748:Tetracaine / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D005782:Gels; D013748:Tetracaine
vernacular_title: Estudio presivo del canal anal en pacientes con hemorroides o con fisura anal. Efecto de la aplicación tópica de un gel anestésico.