title: Tissue specificity of low-field-strength magnetization transfer contrast imaging.
abstract: The time-dependent saturation transfer technique was used to measure the transfer of magnetization in several rat tissues at 0.1 T. The length of the saturation pulse was varied from 0 to 510 msec. The magnetization transfer contrast effect was characteristic for each type of tissue. A substantial reduction of image intensity was obtained in skeletal muscle (74%), heart (71%), spleen (64%), brain (65%), pancreas (64%), liver (64%), kidneys (62%), and lungs (56%) with the longest saturation pulse available. Much smaller declines occurred in stagnant blood and peritoneal fat. The potential of this imaging technique for clinical conditions is discussed.
authors.affiliation: Department of Diagnostic Radiology, Turku University Hospital, Finland.
authors.forename: P T
authors.initials: PT
authors.lastname: Niemi
authors.forename: M E
authors.initials: ME
authors.lastname: Komu
authors.forename: S K
authors.initials: SK
authors.lastname: Koskinen
mesh_terms: D000818:Animals; D066298:In Vitro Techniques; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013552:Swine; D014781:Viscera / Q000033:anatomy & histology*