title: [Silicone breast implants and collagen diseases].
abstract: Connective tissue disease has been reported to occur following implantation of silicone gel-filled prostheses to augment the breast. In this case report and review of the literature, two patients are described in whom connective tissue disease developed within one and three years respectively after cosmetic surgery. One developed dermatomyositis with lung fibrosis, and the other developed cutaneous lupus and a Sjögren-like syndrome. Both suffered serious complications due to vasculitis. Although evidence of a causal relationship between the implantation and the development of connective tissue disease is circumstantial, removal of the silicone prosthesis has been reported to result in subsequent remission.
authors.affiliation: Revmatologisk avdeling, Haukeland sykehus, Bergen.
authors.forename: H J
authors.initials: HJ
authors.lastname: Haga
authors.forename: P
authors.initials: P
authors.lastname: Haaland
authors.forename: T
authors.initials: T
authors.lastname: Haga
mesh_terms: D000328:Adult; D000792:Angiography; D003095:Collagen Diseases / Q000139:chemically induced*; D003882:Dermatomyositis / Q000139:chemically induced; D005260:Female; D005782:Gels; D006225:Hand / Q000098:blood supply; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced; D016462:Mammaplasty / Q000009:adverse effects*; D008875:Middle Aged; D019736:Prostheses and Implants / Q000009:adverse effects*; D012828:Silicones / Q000009:adverse effects*; D014657:Vasculitis / Q000139:chemically induced
chemical_list: D005782:Gels; D012828:Silicones
vernacular_title: Silikon mammaproteser og kollagene sykdommer.