[The place of radioimmunoscintigraphy in the diagnosis and follow-up of ovarian cancer in comparison with computed tomography and second-look surgery].
In this prospective study the diagnostic capability of radioimmunoscintigraphy (RIS) was compared with that of computed tomography (CT) and of "second look" surgery as primary diagnostic procedures in 27 patients and in the follow-up of 52 women suspected of suffering from ovarian cancer. The results were compared with immunohistochemical findings and CA125 serum levels. For primary diagnosis sensitivity, specificity and diagnostic accuracy of RIS was 100%, 60% and 90%, resp. In follow-up, sensitivity for local recurrencies was 75% and specificity 68%. Peritoneal carcinosis in the pelvis and lower abdominal region was better detectable by RIS, but for detection of liver metastases CT showed better results. CT and RIS could not replace "second look" surgery.
Barzen
G
G
Strahlenklinik und Poliklinik, Freie Universität Berlin, FRG.
Friedmann
W
W
Richter
W
W
Schönegg
W
W
Riess
H
H
Eichstädt
H
H
Lichtenegger
W
W
Felix
R
R
D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007457:Iodine Radioisotopes; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000453:epidemiology; D011446:Prospective Studies; D016719:Radioimmunodetection; D012086:Reoperation; D014057:Tomography, X-Ray Computed
D007457:Iodine Radioisotopes
Stellenwert der Radioimmunszintigraphie in der Diagnostik und Verlaufskontrolle des Ovarialkarzinoms im Vergleich zur Computertomographie und "Second Look"-Operation.