title: Changing pattern of brain hemorrhage during 12 years of computed axial tomography.
abstract: OBJECTIVE
  We examined whether the pattern of cerebral hemorrhage changed after the introduction of computed tomography.
  
  
  METHODS
  Using a prospective data base we analyzed the case-fatality ratio, early mortality, and the incidences of hypertension and anticoagulant medication in 488 consecutive cases with supratentorial hemorrhage between 1978 and 1989. Blood pressure at admission of all patients for the years 1978-1979 and 1988-1989 and the Mathew and activities of daily living scores for the years 1978-1979, 1982-1983, and 1988-1989 were assessed retrospectively.
  
  
  RESULTS
  The case-fatality ratio decreased from 49% in the period 1978-1981 to 31% in 1986-1989 (p = 0.006); early mortality (day 1-4) decreased from 28% to 12% (p = 0.0017). The incidence of hypertension decreased from 78% in the period 1978-1981 to 64% in 1986-1989 (p = 0.01). Systolic and diastolic blood pressure at admission sank (p = 0.09). The decrease of the case-fatality ratio correlated best with a less severe initial disturbance of consciousness (p less than 0.01) and with a higher Mathew score (p = 0.038). The activities of daily living score remained unchanged.
  
  
  CONCLUSIONS
  The case-fatality ratio and early mortality decreased after the introduction of computed tomography. This was basically due to a decreased incidence of comatose and stuporous patients with severe neurological deficit paralleled by a decrease of mean systolic and diastolic blood pressure values at admission.
authors.affiliation: Department of Neurology, Justus-Liebig-University Giessen, FRG.
authors.forename: H
authors.initials: H
authors.lastname: Schuetz
authors.forename: T
authors.initials: T
authors.lastname: Dommer
authors.forename: R H
authors.initials: RH
authors.lastname: Boedeker
authors.forename: M
authors.initials: M
authors.lastname: Damian
authors.forename: P
authors.initials: P
authors.lastname: Krack
authors.forename: W
authors.initials: W
authors.lastname: Dorndorf
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use; D002543:Cerebral Hemorrhage / Q000139:chemically induced / Q000000981:diagnostic imaging* / Q000401:mortality / Q000503:physiopathology; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000453:epidemiology; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D016019:Survival Analysis; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D000925:Anticoagulants