[Trisomy 18 (Edwards syndrome): two case reports].
Edwards (or trisomy 18) syndrome, with a frequency of about 1 over 8000 births, is commonly characterized by a very short survival; those rare cases reported with ages of 12 months or more, always were demonstrated to be chromosomic mosaicisms. Two affected children with completely different outcomes are here described; the first with a classic short-life evolution, in opposition to the second with long survival, the last a good example of all those various biological, psychological and social support interventions in these circumstances, very rare to match with, for this appears to be a trisomy 18 without mosaicism.
Morosini
P
P
Divisione di Patologia Neonatale, Ospedale Maggiore di Lodi Mi, Italia.
Verdura
C
C
Paolillo
F
F
Fornari
M
M
Argentiero
M L
ML
Belloni
C
C
D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D002887:Chromosomes, Human, Pair 18; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D014314:Trisomy
La trisomia 18 (sindrome di Edwards): considerazioni su due casi.