Diabetic pregnancy: evidence of selection on the Rh blood group system.
The blood glucose levels of pregnant women with insulin-dependent diabetes mellitus and the blood glucose levels of newborns during the first few hours of life show an association with maternal Rh genotype. Distortions of joint maternal-fetal Rh phenotype distribution have also been observed. Because a cluster of genes involved in glycide metabolism is located on the short arm of chromosome 1, the present observations may reflect the action of these genes.
Gloria-Bottini
F
F
Division of Biometry and Human Development, School of Medicine, 2d University of Rome, Italy.
Gerlini
G
G
Amante
A
A
Pascone
R
R
Bottini
E
E
D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000453:epidemiology / Q000235:genetics*; D005260:Female; D005838:Genotype; D006239:Haplotypes; D006801:Humans; D007003:Hypoglycemia / Q000453:epidemiology; D007231:Infant, Newborn; D010641:Phenotype; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000097:blood / Q000453:epidemiology / Q000235:genetics*; D012204:Rh-Hr Blood-Group System / Q000235:genetics*; D012384:Rome / Q000453:epidemiology; D012641:Selection, Genetic
D001786:Blood Glucose; D012204:Rh-Hr Blood-Group System