title: [Collection of fetal cord blood for karyotyping].
abstract: Cordocentesis was performed in 234 pregnancies (241 fetuses) for rapid karyotyping. The indication was in 86% of cases: abnormal ultrasound. The abnormality encountered were IUGR (85 fetuses) or morphologic abnormality of the pregnancy (130 fetuses). The other indications were maternal mosaicism, mosaicism in cultured amniotic cells, maternal age (late booking), fragile X syndrome, confirmation of abnormal karyotype obtained by amniocentesis. The fetal karyotype was established in 97.5% (6 failures), 18 karyotypes were abnormal in the group "abnormal ultrasound" (208 pregnancies, 8.6%; 215 fetuses, 8.3%). No maternal complication were observed, there were 6 fetal losses (2.5%).
authors.affiliation: Service de Gynécologie-Obstétrique, Hôpital Erasme, Bruxelles.
authors.forename: C
authors.initials: C
authors.lastname: Donner
authors.forename: F
authors.initials: F
authors.lastname: Avni
authors.forename: R
authors.initials: R
authors.lastname: Karoubi
authors.forename: P
authors.initials: P
authors.lastname: Simon
authors.forename: E
authors.initials: E
authors.lastname: Vamos
authors.forename: N
authors.initials: N
authors.lastname: Van Regemorter
authors.forename: F
authors.initials: F
authors.lastname: Rodesch
mesh_terms: D001800:Blood Specimen Collection / Q000379:methods* / Q000592:standards; D005069:Evaluation Studies as Topic; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D005315:Fetal Diseases / Q000097:blood* / Q000000981:diagnostic imaging / Q000453:epidemiology; D006801:Humans; D007621:Karyotyping / Q000379:methods*; D008403:Mass Screening / Q000379:methods / Q000592:standards; D011247:Pregnancy; D012680:Sensitivity and Specificity; D016216:Ultrasonography, Prenatal / Q000592:standards
vernacular_title: Prélèvement de sang foetal par cordocentèse pour établissement du caryotype.