Blood flow and skeletal muscle in patients with heart failure.
The factors that contribute to the symptoms of breathlessness and fatigue, and that limit exercise capacity in patients with chronic heart failure are poorly understood. Recent evidence suggests that the major mechanism is not related to central hemodynamics but to a reduction of skeletal muscle mass and diminished blood flow to skeletal muscle on exercise.
Poole-Wilson
P A
PA
National Heart and Lung Institute, London, England.
Buller
N P
NP
Lindsay
D C
DC
D004417:Dyspnea / Q000503:physiopathology; D005080:Exercise Test; D006333:Heart Failure / Q000175:diagnosis / Q000503:physiopathology*; D006801:Humans; D009132:Muscles / Q000098:blood supply*; D009133:Muscular Atrophy / Q000503:physiopathology; D010101:Oxygen Consumption / Q000502:physiology; D012039:Regional Blood Flow / Q000502:physiology