title: Microvillus growth and M-cell formation in mouse Peyer's patch follicle-associated epithelial tissue.
abstract: Development of microvillus structure on the surface of enterocytes migrating over follicle-associated lymphoid tissue appears to take place in an identical way to that seen on villus enterocytes. M-cells, which are not found in crypts, possess microvilli of constant length in all parts of the follicle dome epithelial tissue. The surface area of M-cell microvilli is not however different from that determined on fully formed follicle-associated enterocytes. These results support the hypothesis that M-cell formation takes place throughout the dome epithelium by immune-induced transformation of already existing enterocytes.
authors.affiliation: Department of Cell Biology, AFRC Institute of Animal Physiology and Genetics Research, Babraham, Cambridge.
authors.forename: M W
authors.initials: MW
authors.lastname: Smith
authors.forename: M A
authors.initials: MA
authors.lastname: Peacock
mesh_terms: D000818:Animals; D004848:Epithelium / Q000648:ultrastructure; D005260:Female; D051379:Mice; D008871:Microvilli / Q000648:ultrastructure; D010581:Peyer's Patches / Q000166:cytology / Q000648:ultrastructure*