Extranodal Rosai-Dorfman disease: an uncommon cause of persistent nodule in the ear.
A 40-year-old woman presented with a nodule over the tragus of the right ear. A biopsy was initially reported as showing non-specific inflammation. In view of the persistence of the lesion, the histological material was reviewed, leading to revision of the diagnosis to Rosai-Dorfman disease, a diagnosis further confirmed by immunoreactivity of the histiocytes for S-100 protein. This case represented the extranodal form of Rosai-Dorfman disease in the absence of lymph node involvement.
Tsang
W Y
WY
Institute of Pathology, Queen Elizabeth Hospital, Kowloon, Hong Kong.
Chan
J K
JK
Ho
W K
WK
Yu
H C
HC
Chow
L T
LT
D000328:Adult; D004427:Ear Diseases / Q000473:pathology; D004431:Ear, External / Q000473:pathology*; D005260:Female; D006644:Histiocytes / Q000473:pathology; D015618:Histiocytosis, Sinus / Q000473:pathology*; D006801:Humans