Natural IgM play a major role in hyperacute rejection of discordant heart xenografts.
Gambiez
L
L
Laboratoire d'Immunologie, Faculté Cochin, Paris, France.
Salamé
E
E
Chéreau
C
C
Calmus
Y
Y
Ayani
E
E
Houssin
D
D
Weill
B
B
D000818:Animals; D001011:Aorta; D001666:Binding Sites, Antibody; D002478:Cells, Cultured; D004730:Endothelium, Vascular / Q000276:immunology; D006084:Graft Rejection / Q000276:immunology*; D006168:Guinea Pigs; D016027:Heart Transplantation / Q000276:immunology*; D007140:Immunoglobulin Fab Fragments / Q000276:immunology; D007074:Immunoglobulin G / Q000276:immunology / Q000378:metabolism; D007075:Immunoglobulin M / Q000276:immunology* / Q000378:metabolism; D007148:Immunoglobulin mu-Chains / Q000276:immunology; D051381:Rats; D011917:Rats, Inbred Lew; D014183:Transplantation, Heterologous / Q000276:immunology*
D007140:Immunoglobulin Fab Fragments; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007148:Immunoglobulin mu-Chains