title: [A case report of thrombosed St. Jude Medical valve in a patient with macroglobulinemia].
abstract: A 66-year-old man who had undergone MVR using a ST. Jude Medical valve entered the hospital with acute heart failure and cardiogenic shock 3 months after surgery. He had had a symptom of petechiae due to macrogloburinemia after initial MVR and had been in the poor control of anticoagulation therapy because of presence of petechiae. He was diagnosed as prosthetic valve thrombosis using echocardiography and underwent emergency re-MVR using a Central Open Bioprosthesis (COB) which was developed by our department. He was doing well 8 month after re-MVR. Selection of prosthetic valve should be performed carefully in the patient with hemorrhagic disease, and careful observation and proper anticoagulant therapy should be carried out after valve replacement.
authors.affiliation: Department of Cardiovascular Surgery, Heart Institute of Japan, Tokyo Women's Medical College.
authors.forename: T
authors.initials: T
authors.lastname: Takemura
authors.forename: A
authors.initials: A
authors.lastname: Shiikawa
authors.forename: M
authors.initials: M
authors.lastname: Kitamura
authors.forename: S
authors.initials: S
authors.lastname: Aomi
authors.forename: M
authors.initials: M
authors.lastname: Endo
authors.forename: A
authors.initials: A
authors.lastname: Hashimoto
authors.forename: H
authors.initials: H
authors.lastname: Koyanagi
mesh_terms: D000368:Aged; D001705:Bioprosthesis; D006333:Heart Failure / Q000209:etiology / Q000601:surgery*; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000601:surgery; D008944:Mitral Valve Insufficiency / Q000601:surgery; D011475:Prosthesis Failure; D012086:Reoperation; D013927:Thrombosis / Q000209:etiology / Q000601:surgery; D008258:Waldenstrom Macroglobulinemia / Q000150:complications*; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D014859:Warfarin