Inadvertent administration of prostaglandin E1 instead of prostaglandin F2 alpha in a patient with uterine atony and hemorrhage.
A woman underwent cesarean delivery for premature labor, breech presentation, and ruptured membranes. Placenta accreta associated with uterine atony and severe hemorrhage was diagnosed. Prostaglandin E1 instead of prostaglandin F2 alpha was inadvertently administered in an effort to control the hemorrhage. The resulting complications included profound hypotension, disseminated intravascular coagulation, and ventricular tachycardia.
Reedy
M B
MB
Department of Obstetrics and Gynecology, Scott and White Clinic, Scott, Sherwood, and Brindley Foundation, Texas A&M University College of Medicine, Temple.
McMillion
J S
JS
Engvall
W R
WR
Sulak
P J
PJ
Fisher
N L
NL
D000328:Adult; D000527:Alprostadil / Q000008:administration & dosage* / Q000009:adverse effects; D015237:Dinoprost / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008508:Medication Errors; D007752:Obstetric Labor, Premature / Q000628:therapy*; D010921:Placenta Accreta / Q000150:complications; D011247:Pregnancy; D014592:Uterine Hemorrhage / Q000188:drug therapy* / Q000209:etiology; D014593:Uterine Inertia / Q000150:complications / Q000188:drug therapy*
D015237:Dinoprost; D000527:Alprostadil