[Torsades de pointes heart arrhythmia caused by terodiline].
An 88-year old woman was prescribed treatment with terodilin for urge incontinence. The drug was administered daily by a nurse. About a fortnight later she had several syncopes in the course of three to four days. On admission to hospital the electrocardiogram showed recurring torsades de pointes ventricular tachycardias. Ventricular pacing prevented any further arrhythmia. An internal pacemaker was therefore implanted. The QT-interval was probably prolonged after two weeks on terodilin compared with the interval shown on an electrocardiogram taken earlier.
Braadland
H
H
Medisinsk etterbehandling, og rehabilitering 1K, Klinikk for geriatri og rehabilitering, Ullevål sykehus, Oslo.
D000368:Aged; D002082:Butylamines / Q000009:adverse effects*; D002121:Calcium Channel Blockers / Q000009:adverse effects*; D005260:Female; D006801:Humans; D010138:Pacemaker, Artificial; D016171:Torsades de Pointes / Q000139:chemically induced* / Q000503:physiopathology / Q000628:therapy
D002082:Butylamines; D002121:Calcium Channel Blockers; C010637:terodiline
Torsades de pointes hjertearytmi utløst av terodilin.