Verapamil and valproic acid treatment of prolonged mania.
The case of an adolescent with severe mental retardation, blindness, and a complex of behavioral symptoms consistent with mania is reported. Symptoms include an increased activity level, mood liability, irritability, hyposomia, and severe self-injurious behavior. The successful use of verapamil and valproic acid in the treatment of prolonged mania in this child is described.
Kastner
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Columbia University College of Physicians and Surgeons.
Friedman
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DL
D000293:Adolescent; D001143:Arousal / Q000187:drug effects; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000523:psychology; D004359:Drug Therapy, Combination; D006801:Humans; D008607:Intellectual Disability / Q000188:drug therapy*; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D019965:Neurocognitive Disorders / Q000188:drug therapy / Q000523:psychology; D014635:Valproic Acid / Q000008:administration & dosage*; D014700:Verapamil / Q000008:administration & dosage*
D014635:Valproic Acid; D014700:Verapamil