Quantitative radio-isotope scanning of the sacroiliac joints in ankylosing spondylitis.
A method for applying 99mTc-MDP for dynamic and static quantitative radioisotope scanning (QRS) of the sacroiliac joints (SI) in early progressive sacroiliitis in ankylosing spondylitis (AS) is described. In a prospective study, 2 groups of male AS patients were investigated, one with increased elevated erythrocytic sedimentation rate (ESR) (group A, n = 7) and one with normal ESR (group B, n = 8). In both groups an increased uptake of the radiotracer was found in the static part of the study versus a control group C (n = 9). An increased uptake versus group C was also found for group A in the dynamic part of the study (p = 0.01) while there was no significant difference dynamically between groups B and C. The results of the dynamic study in group A indicate ESR to be a parameter of inflammatory activity in the SI joints. The study also seems to indicate QRS to be a valuable diagnostic method in early AS without definite radiographic changes in the SI joints.
Skaar
O
O
Department of Radiology, Oslo Sanitetsforening Rheumatism Hospital, Norway.
Dale
K
K
Lindegaard
M W
MW
Førre
O
O
Kåss
E
E
D000328:Adult; D001799:Blood Sedimentation; D006801:Humans; D008297:Male; D011446:Prospective Studies; D011877:Radionuclide Imaging; D012446:Sacroiliac Joint / Q000000981:diagnostic imaging*; D013167:Spondylitis, Ankylosing / Q000097:blood / Q000000981:diagnostic imaging*; D013669:Technetium Tc 99m Medronate
D013669:Technetium Tc 99m Medronate