A rationale for the use of non-steroidal anti-androgens in the management of prostate cancer.
Flutamide is a non-steroidal anti-androgen which has been used to treat prostate cancer. Results to date indicate that flutamide is as effective as other conventional therapy. It has only moderate activity in patients in whom conventional hormonal therapy has previously failed, but appears to be beneficial when combined with an LHRH agonist.
Benson
R C
RC
Center for Urological Treatment and Research, Nashville, Tennessee 37203.
D000818:Animals; D005485:Flutamide / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000188:drug therapy*
D005485:Flutamide