title: Preparation and investigation of inclusion complexes containing nitrazepam.
abstract: Nitrazepam is a valuable drug, being one of the often used minor tranquillizers in psychotherapy. However, its solubility characteristics are very unfavourable. Products were prepared with dimethyl-beta-cyclodextrin in different combinations (8.58%, 19.48% and 27.29%) and by several methods such as mixing, kneading, precipitation and spray-drying.
authors.affiliation: Department of Pharmaceutical Technology, Albert Szent-Györgyi Medical University, Szeged.
authors.forename: G
authors.initials: G
authors.lastname: Czékus
authors.forename: N
authors.initials: N
authors.lastname: Jung
authors.forename: M
authors.initials: M
authors.lastname: Kata
mesh_terms: D003505:Cyclodextrins / Q000737:chemistry; D009567:Nitrazepam / Q000737:chemistry*; D012995:Solubility
chemical_list: D003505:Cyclodextrins; D009567:Nitrazepam