[Cell kinetics of lens epithelial cells on the whole-mount preparation (3). Changes in mouse cataract lens by feeding galactose].
In this study, we used ICR (Institute of Cancer Research) strain mouse because they showed hypergalactosemia but not cataractogenesis. We examined the proliferative ability of the lens epithelial cells by means of a whole-mount preparation of epithelium and 3H-thymidine autoradiography. An increased number of labelled cells was not found in the mouse. The increased proliferative ability of epithelial cells in rat galactose cataract did not seem to be caused by hypergalactosemia.
Terubayashi
H
H
Department of Ophthalmology, Kyoto Prefectural University of Medicine, Japan.
Tsutsumi
M
M
Okamoto
S
S
Ikebe
H
H
Akagi
Y
Y
D000284:Administration, Oral; D000821:Animal Feed; D000818:Animals; D002386:Cataract / Q000139:chemically induced / Q000473:pathology*; D002453:Cell Cycle; D003584:Cytological Techniques; D004848:Epithelium / Q000187:drug effects / Q000473:pathology; D005690:Galactose / Q000008:administration & dosage; D005693:Galactosemias / Q000150:complications / Q000473:pathology; D007908:Lens, Crystalline / Q000187:drug effects / Q000473:pathology*; D051379:Mice; D008813:Mice, Inbred ICR
D005690:Galactose