[Alcohol drinking and intrauterine dystrophia. Effects and significance in infancy].
In a prospective study intrauterine growth retardation (IUGR) (less than 10. growth percentile at birth) was used as a predictor to diagnose intrauterine alcohol exposure. An interview about maternal alcohol consumption was performed prenatally--when IUGR was diagnosed by ultrasound--or postnatally. The children were followed up to 18 months of age. In 6/47 children we diagnosed various degrees of the Fetal Alcohol Syndrome FAS, with only one patient showing a full blown syndrome at birth. 5 patients could not be identified until the pediatric reexamination at the age of 8-18 months. IUGR and a maternal history of even moderate drinking during pregnancy should emphasize the possibility of an intrauterine alcohol damage, even in a normal child at birth.
Schöneck
U
U
Universitätsklinikum Rudolf Virchow, Berlin.
Spohr
H L
HL
Willms
J
J
Steinhausen
H C
HC
D000428:Alcohol Drinking / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000009:adverse effects; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000175:diagnosis*; D005317:Fetal Growth Retardation / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009460:Neurologic Examination; D007752:Obstetric Labor, Premature / Q000209:etiology; D011247:Pregnancy; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects
D000431:Ethanol
Alkoholkonsum und intrauterine Dystrophie. Auswirkungen und Bedeutung im Säuglingsalter.