The antiphospholipid syndrome: the clot thickens.
The "Antiphospholipid Syndrome" is a disorder that mainly affects young people. Recurrent venous or arterial thrombosis, recurrent fetal loss, and thrombocytopenia are the primary features. The diagnosis is established by the presence of the anticardiolipin (aCL) antibody or the lupus anticoagulant (LA). Treatment is symptomatic.
Gleason
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Department of Medicine, University of Louisville, KY 40292.
Harris
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D001323:Autoantibodies / Q000032:analysis*; D002308:Cardiolipins / Q000276:immunology; D005260:Female; D005313:Fetal Death / Q000276:immunology; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000032:analysis; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis / Q000276:immunology*; D008297:Male; D010314:Partial Thromboplastin Time; D010743:Phospholipids / Q000276:immunology*; D010920:Placenta / Q000098:blood supply; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000276:immunology*; D013577:Syndrome; D013927:Thrombosis / Q000175:diagnosis / Q000276:immunology*
D001323:Autoantibodies; D002308:Cardiolipins; D016682:Lupus Coagulation Inhibitor; D010743:Phospholipids