A child with xeroderma pigmentosum and bone marrow failure.
The case of a child with both xeroderma pigmentosum and bone marrow failure is reported. It is suggested that this is not a chance association, and that the bone marrow hypoplasia may reflect an increased susceptibility of this patient's haemopoietic stem cells to non-UV mutagens.
Salob
S P
SP
Department of Dermatology, Hospitals for Sick Children, London, U.K.
Webb
D K
DK
Atherton
D J
DJ
D000741:Anemia, Aplastic / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D001853:Bone Marrow / Q000473:pathology; D002648:Child; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D010110:Oxymetholone / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use; D012867:Skin / Q000473:pathology; D014983:Xeroderma Pigmentosum / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
D011239:Prednisolone; D010110:Oxymetholone