Position of double bond of trans isomers of linoleic acid affects fatty acid desaturation and elongation.
The position of the trans double bond of linoleic acid isomers affects the incorporation of the isomers in tissue lipids and their metabolic conversion to other metabolites. The 9 trans, 12 cis isomer of linoleic acid is a poor substrate and the 9 cis, 12 trans isomer is a good substrate for the enzyme that desaturates dienoic acids at position six.
D000818:Animals; D004042:Dietary Fats, Unsaturated / Q000378:metabolism*; D005227:Fatty Acids / Q000737:chemistry / Q000378:metabolism*; D007536:Isomerism; D019787:Linoleic Acid; D008041:Linoleic Acids / Q000737:chemistry* / Q000378:metabolism; D050356:Lipid Metabolism; D008968:Molecular Conformation
D004042:Dietary Fats, Unsaturated; D005227:Fatty Acids; D008041:Linoleic Acids; D019787:Linoleic Acid