title: The effect of hyperosmolarity on muscle glycogen accumulation.
abstract: Soleus (red) and extensor digitorum longus (white) muscles from Sprague Dawley rats were incubated with 6-14C-labelled glucose in normal and in hyperosmotic media. Hyperosmolarity decreased 6-14C-glucose incorporation into muscle glycogen in a dose dependent manner and increased glycolysis and glucose oxidation. Increased glycogenolysis rather than decreased glycogenesis was responsible for the reduction in labelled glycogen accumulation.
authors.affiliation: Department of Medicine, Medical College of Virginia, Richmond.
authors.forename: J
authors.initials: J
authors.lastname: Li
authors.forename: J S
authors.initials: JS
authors.lastname: Stillman
authors.forename: J N
authors.initials: JN
authors.lastname: Clore
authors.forename: W G
authors.initials: WG
authors.lastname: Blackard
mesh_terms: D000818:Animals; D006003:Glycogen / Q000378:metabolism*; D066298:In Vitro Techniques; D008297:Male; D009132:Muscles / Q000378:metabolism*; D009994:Osmolar Concentration; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D006003:Glycogen