title: Leiomyosarcoma: a rare pedal finding.
abstract: Leiomyosarcoma of the skin and subcutaneous tissue is a rare soft tissue neoplasm comprised of spindle-shaped smooth muscle cells. The statistical incidence of superficial leiomyosarcomas varies from 2.3% to 5.3% of malignant soft tissue tumors and from 4.0% to 6.5% of soft tissue sarcomas. Its occurrence in the foot is even more unusual. In a literature review extending from 1936-present, the authors have been able to locate only 12 known cases of leiomyosarcoma involving the foot and ankle. A presentation of the incidence, demographics of distribution, clinical characteristics, histopathologic features, prognosis, and treatment of leiomyosarcoma will be presented along with a unique case history involving a recalcitrant heel ulcer complicated by leiomyosarcoma.
authors.affiliation: Department of Podiatric Surgery, West Jersey Health System, Camden 08104.
authors.forename: T R
authors.initials: TR
authors.lastname: Gunzy
authors.forename: P R
authors.initials: PR
authors.lastname: Quintavalle
authors.forename: F J
authors.initials: FJ
authors.lastname: Tursi
mesh_terms: D000368:Aged; D005534:Foot Diseases / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D006365:Heel; D006801:Humans; D007890:Leiomyosarcoma / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D008297:Male; D011379:Prognosis; D012008:Recurrence; D012983:Soft Tissue Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D015996:Survival Rate