title: [Laryngeal cancer following gunshot injury and paraffin injection].
abstract: Subcutaneous and submucosal injections of paraffin were a wide-spread technique in plastic and reconstructive surgery during the early decades of this century. Intralaryngeal injections were applied to patients suffering from paralysis of one vocal cord or a defect resulting from perforating trauma, intending improvement of the voice. This method was widely abandoned within the fifties when severe complications like foreign-body granuloma and carcinoma developed in patients undergoing paraffin injections. The development of cancer after a trauma is a common question in expert reports. We report the case of a patient who developed carcinoma of the vocal cord 49 years after perforation of the larynx by a shot with consecutive injection of paraffin. The relationship between trauma, injections of paraffin and cancer is discussed and consequences on diagnostics and treatment of risk patients are outlined.
authors.affiliation: HNO-Klinik, Albert-Ludwigs-Universität Freiburg.
authors.forename: W
authors.initials: W
authors.lastname: Maier
authors.forename: C
authors.initials: C
authors.lastname: Beck
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000139:chemically induced* / Q000473:pathology; D002471:Cell Transformation, Neoplastic / Q000139:chemically induced / Q000473:pathology; D006801:Humans; D007822:Laryngeal Neoplasms / Q000139:chemically induced* / Q000473:pathology; D007828:Laryngoscopy; D007830:Larynx / Q000187:drug effects / Q000293:injuries* / Q000473:pathology; D008297:Male; D010232:Paraffin / Q000008:administration & dosage / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed; D014948:Wounds, Gunshot / Q000473:pathology / Q000601:surgery*
chemical_list: D010232:Paraffin
vernacular_title: Larynxkarzinom nach Schussverletzung und Paraffininjektion.