High-performance liquid chromatographic determination of ciprofloxacin in plasma.
This paper describes an accurate, specific and sensitive high-performance liquid chromatographic (HPLC) method for the determination of ciprofloxacin in small samples (0.5 ml). The samples, after pretreatment by solvent extraction, were eluted on a reversed-phase column and detected by an ultraviolet detector. The results obtained on patient samples are presented.
Mehta
A C
AC
Department of Pharmacy, General Infirmary, Leeds, Yorkshire, U.K.
Hart-Davies
S
S
Kay
E A
EA
D002851:Chromatography, High Pressure Liquid; D002939:Ciprofloxacin / Q000097:blood*; D006801:Humans
D002939:Ciprofloxacin