Fatal co-infection with pulmonary tuberculosis and herpes simplex virus 1 pneumonia under steroid treatment.
We report a case of adult respiratory distress syndrome in a 65 yr old man under inappropriate steroid therapy who developed both Herpes simplex virus 1 (HSV) and Mycobacterium tuberculosis pneumonia; we conclude from clinical and histological data that HSV 1 played a major role in the fatal outcome of this immunocompromised patient, in spite of acyclovir treatment.
Charasse
C
C
Service de Réanimation Médicale et Maladies Infectieuses, Hôpital Pontchaillou, Universite de Rennes, France.
Liégaux
J M
JM
Le Tulzo
Y
Y
Camus
C
C
Thomas
R
R
Cartier
F
F
Ramée
M P
MP
André
P
P
D000368:Aged; D006561:Herpes Simplex / Q000150:complications* / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000009:adverse effects*; D011024:Pneumonia, Viral / Q000150:complications* / Q000209:etiology / Q000382:microbiology; D012128:Respiratory Distress Syndrome / Q000175:diagnosis / Q000209:etiology*; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000175:diagnosis / Q000209:etiology
D008775:Methylprednisolone