Hemicrania continua: a case responsive to piroxicam-beta-cyclodextrin.
The case of a 53-year-old woman is described, who since the age of 38 years had been suffering from a unilateral headache that was at first remitting, but then evolved into an unremitting course. The headache was burning in quality, located in the left forehead and face, and was accompanied by mild ipsilateral autonomic symptoms. The clinical picture, as well as the absolute response to indomethacin, suggested a diagnosis of hemicrania continua. The presence of mild gastric discomfort on continuous indomethacin administration made us transfer the patient to another NSAID (piroxicam-beta-cyclodextrin). With this drug, complete relief and good tolerability was obtained.
Trucco
M
M
Department of Neurology, Ospedali Riuniti di Pietra e Finale Ligure, Italy.
Antonaci
F
F
Sandrini
G
G
D002908:Chronic Disease; D003505:Cyclodextrins / Q000627:therapeutic use*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007213:Indomethacin / Q000009:adverse effects / Q000627:therapeutic use; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy* / Q000503:physiopathology; D010894:Piroxicam / Q000627:therapeutic use*; D013272:Stomach Diseases / Q000139:chemically induced; D047392:beta-Cyclodextrins
D003505:Cyclodextrins; D004338:Drug Combinations; D047392:beta-Cyclodextrins; D010894:Piroxicam; C031215:betadex; D007213:Indomethacin