Molecular events in the development of the lymphocyte repertoire.
Last autumn, an international cast of molecular geneticists and immunologists coalesced around the comfortable Bishenberg Centre in the hills of Alsace to assess various aspects of the expression and development of the lymphocyte repertoire*. Here, progress in the understanding of control of genomic rearrangements and development of the lymphocyte repertoire are described.
Zouali
M
M
Institut Pasteur, Immunogénétique Cellulaire, Paris, France.
MacLennan
I C
IC
D000818:Animals; D001402:B-Lymphocytes / Q000502:physiology*; D004268:DNA-Binding Proteins; D018398:Homeodomain Proteins; D008213:Lymphocyte Activation / Q000502:physiology; D011506:Proteins / Q000235:genetics; D013601:T-Lymphocytes / Q000502:physiology*
D004268:DNA-Binding Proteins; D018398:Homeodomain Proteins; D011506:Proteins; C064655:V(D)J recombination activating protein 2; C064658:RAG-1 protein