The prevalence of Toxoplasma infection among pregnant women in Ibadan, Nigeria.
The seroprevalence of toxoplasmosis in pregnant women from the inner area of Ibadan was determined by the dye test. Two hundred and seventy-three of the 352 women (78%) had dye test titres of 1/16 or greater with 165 (47%) having titres of 1/128 or greater. In contrast, 42 of 192 pregnant women (22%) from the Swansea area of the UK were dye test positive with only six (3%) having titres of 1/128. The possibility that reinfection or recrudescence is responsible for maintaining high antibody levels in African women and the consequence of this high level of infection in relation to potential human immune deficiency virus (HIV) infections are discussed. Social and environmental conditions indicate that the source of infection is contact with cat faeces.
Onadeko
M O
MO
University College Hospital, Ibadan, Nigeria.
Joynson
D H
DH
Payne
R A
RA
D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D000013:Congenital Abnormalities; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005313:Fetal Death; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D009549:Nigeria; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*; D015995:Prevalence; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000453:epidemiology*
D000913:Antibodies, Protozoan; D007075:Immunoglobulin M