[Chemical investigation of naturally occurring drug materials. Elucidation of scientific basis for traditional medicines and exploitation of new naturally occurring drugs].
In search of new biologically active compounds in nature, we have been investigating naturally occurring substances on the following subjects: I. chemical studies on naturally occurring drug materials [a) elucidation of bioactive constituents in natural drugs, b) elucidation of scientific basis for crude drug processing, and c) investigation of bioactive constituents in food materials], II. exploitation of new pharmaceuticals in nature [a) investigation of marine natural products and b) exploitation of Indonesian medicinal plants], and III. synthetic studies on bioactive natural products [a) chemical modification of naturally abundant carbohydrates and terpenoids and b) synthetic studies of complex lipids]. This article reviews the results obtained in our laboratory since 1978 on the subjects of I-a, b, c, II-a, and III-a.
Kitagawa
I
I
Faculty of Pharmaceutical Sciences, Osaka University, Japan.
D000470:Alkaloids / Q000032:analysis / Q000737:chemistry; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000494:pharmacology / Q000627:therapeutic use; D005947:Glucose / Q000737:chemistry; D008968:Molecular Conformation; D009705:Nucleosides / Q000138:chemical synthesis; D012503:Saponins / Q000032:analysis / Q000737:chemistry
D000470:Alkaloids; D004365:Drugs, Chinese Herbal; D009705:Nucleosides; D012503:Saponins; D005947:Glucose