Septicemia due to Yersinia enterocolitica in a hemodialyzed, iron-depleted patient receiving omeprazole and oral iron supplementation.
Septicemia occurred in a long-term hemodialysis patient on oral iron supplementation who had been treated for esophageal ulcer by omeprazole, an ulcer-healing drug. Yersinia enterocolitica serotype 0:3 was recovered from blood cultures. A raised intraintestinal pH and an increased intraluminal iron load may have been contributing factors for the enhanced proliferation and generalized infection of Y enterocolitica.
Fakir
M
M
Service d'Hémodialyse, Epuration extra-rénale-Médecine interne, Centre Hospitalier de Soissons, Reims, France.
Saison
C
C
Wong
T
T
Matta
B
B
Hardin
J M
JM
D000368:Aged; D000747:Anemia, Hypochromic / Q000188:drug therapy; D016470:Bacteremia / Q000382:microbiology*; D004935:Esophageal Diseases / Q000188:drug therapy; D005260:Female; D005296:Ferrous Compounds / Q000627:therapeutic use*; D006801:Humans; D009853:Omeprazole / Q000009:adverse effects / Q000627:therapeutic use*; D006435:Renal Dialysis; D014456:Ulcer / Q000188:drug therapy; D015009:Yersinia Infections / Q000209:etiology*; D015008:Yersinia enterocolitica / Q000302:isolation & purification*
D005296:Ferrous Compounds; D009853:Omeprazole; C031621:ferrous fumarate