title: Endothelin: a long-acting local constrictor hormone.
abstract: Endothelin is a local peptide hormone produced by vascular endothelial cells and is the most potent vasoconstrictor yet identified. There is increasing evidence that endothelin plays a role in the regulation of vascular tone and blood pressure and in the pathophysiology of cardiovascular, renal and respiratory disease.
authors.affiliation: University of Edinburgh, Department of Medicine, Western General Hospital.
authors.forename: W G
authors.initials: WG
authors.lastname: Haynes
authors.forename: D J
authors.initials: DJ
authors.lastname: Webb
mesh_terms: D000595:Amino Acid Sequence; D001249:Asthma / Q000503:physiopathology; D002318:Cardiovascular Diseases / Q000503:physiopathology; D016232:Endothelins / Q000737:chemistry / Q000235:genetics / Q000502:physiology; D006801:Humans; D007674:Kidney Diseases / Q000503:physiopathology; D008969:Molecular Sequence Data; D015398:Signal Transduction
chemical_list: D016232:Endothelins