title: Oxygen saturation during sleep in patients with bronchopulmonary dysplasia.
abstract: We hypothesized that significant sleep desaturation might occur in infants with bronchopulmonary dysplasia whose awake saturations were between 90 and 92%. Supplemental oxygen was continued until the awake saturation on room air was 90% or greater. Sleep saturations were monitored by oximetry sampling for a 3-min period every hour overnight. Significant desaturation was considered to be present if the saturation fell repeatedly below 88%. There were 39 studies performed in room air, and 14 studies in supplemental oxygen. We demonstrated that patients with acceptable awake saturation may desaturate while sleeping. However, only 1 of 25 patients whose saturation in room air was 92% or more repeatedly desaturated during sleep.
authors.affiliation: Department of Pediatrics, McGill University, Montreal Children's Hospital, Canada.
authors.forename: R
authors.initials: R
authors.lastname: Zinman
authors.forename: P W
authors.initials: PW
authors.lastname: Blanchard
authors.forename: F
authors.initials: F
authors.lastname: Vachon
mesh_terms: D001997:Bronchopulmonary Dysplasia / Q000097:blood / Q000503:physiopathology* / Q000628:therapy; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010100:Oxygen / Q000097:blood* / Q000627:therapeutic use; D012189:Retrospective Studies; D012890:Sleep / Q000502:physiology*; D014851:Wakefulness / Q000502:physiology
chemical_list: D010100:Oxygen