[In vivo exploration of glutamine metabolism in man].
Glutamine is the most copious aminoacid in the body where it plays fundamental physiological roles. Its is a precursor of hepatic ureagenesis and renal ammoniagenesis; it acts as cellular fuel in tissues with fast turnover (intestine, skin, immune system) and is a potential regulator of protein synthesis. The sites of production (muscle) and utilization of glutamine have been established by multiple catheterization, while 15N-labelled tracers have made it possible to quantify its role as main inter-organ nitrogen carrier, to determine the origin of nitrogen used in its synthesis and to demonstrate in vivo the utilization of glutamine in the human bowel.
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INSERM U.290 Fonctions Intestinales, Métabolisme et Nutrition, Hôpital St-Lazare, Paris, France.
D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D005973:Glutamine / Q000378:metabolism*; D006801:Humans; D009132:Muscles / Q000378:metabolism*; D009928:Organ Specificity
D000596:Amino Acids; D005973:Glutamine
L'exploration du métabolisme de la glutamine in vivo chez l'homme.