title: Chlorella virus PBCV-1 replication is not affected by cytoskeletal disruptors.
abstract: The majority, if not the entire life cycle, of the large dsDNA-containing algal virus PBCV-1 occurs in localized regions in the cytoplasm. Thirteen drugs that disrupt the cytoskeleton had no effect on PBCV-1 replication at concentrations which inhibited host growth. Therefore, host cytoskeletal elements do not appear to be important in PBCV-1 morphogenesis.
authors.affiliation: Department of Plant Pathology, University of Nebraska, Lincoln 68583-0722.
authors.forename: J W
authors.initials: JW
authors.lastname: Nietfeldt
authors.forename: K
authors.initials: K
authors.lastname: Lee
authors.forename: J L
authors.initials: JL
authors.lastname: Van Etten
mesh_terms: D002708:Chlorella / Q000187:drug effects / Q000648:ultrastructure; D003599:Cytoskeleton / Q000187:drug effects*; D004267:DNA Viruses / Q000187:drug effects* / Q000502:physiology; D014779:Virus Replication / Q000187:drug effects*