The effects of local anesthetics containing epinephrine on digital blood perfusion. 1978.
Digital perfusion research was conducted with two local anesthetics, lidocaine and bupivacaine. The studies were performed utilizing both anesthetic agents, plain and with various concentrations of epinephrine. The drugs' effects on blood perfusion over a 24-hr. period were recorded and discussed. The onset and duration of anesthesia were also compared.
Green
D
D
Department of Surgery, Pennsylvania College of Podiatric Medicine, Philadelphia.
Walter
J
J
Heden
R
R
Menacker
L
L
D000772:Anesthesia, Local / Q000266:history*; D002045:Bupivacaine; D004837:Epinephrine / Q000266:history / Q000494:pharmacology*; D005260:Female; D049673:History, 20th Century; D006801:Humans; D008012:Lidocaine; D008297:Male; D012039:Regional Blood Flow / Q000187:drug effects; D014034:Toes / Q000098:blood supply*; D014661:Vasoconstriction / Q000187:drug effects; D014664:Vasodilation / Q000187:drug effects
D008012:Lidocaine; D002045:Bupivacaine; D004837:Epinephrine