Recovery from widespread bone marrow necrosis occurring after chemotherapy for adult acute monocytic leukemia.
A patient with acute monocytic leukemia who developed bone marrow necrosis following induction chemotherapy is presented. Although the bone marrow necrosis was extensive, recovery occurred, along with complete remission of leukemia. Severe bone marrow necrosis in this setting may be reversible, and continued vigorous supportive care for these patients should be strongly considered.
Sporn
J R
JR
Department of Medicine, University of Connecticut Health Center, Farmington 06030.
Fallon
M A
MA
D000328:Adult; D001853:Bone Marrow / Q000473:pathology*; D001855:Bone Marrow Diseases / Q000209:etiology*; D006801:Humans; D007948:Leukemia, Monocytic, Acute / Q000150:complications / Q000188:drug therapy*; D008297:Male; D009336:Necrosis; D012074:Remission Induction