[The effect of sodium fluoride on energy and protein metabolism in the rat liver after experimental ischemia].
The experimental study of 88 white rats has stated that peroral introduction of sodium fluoride at a rate of 1.2 mg per 100 g of mass in animals during 3 month period is followed by the development of fluoride intoxication, that causes a considerable decrease of liver resistance to ischemia and more vivid disturbances of its energy and protein metabolism. The activity of the restoration plastic processes after ischemia decreases. A conclusion is drawn that fluoride can influence the seriousness of illness, ischemia underlying it.
Tyrtyshnikov
I M
IM
Pedyk
V P
VP
D000818:Animals; D004734:Energy Metabolism / Q000187:drug effects*; D007511:Ischemia / Q000378:metabolism*; D008099:Liver / Q000098:blood supply / Q000187:drug effects* / Q000378:metabolism; D014176:Protein Biosynthesis; D011506:Proteins / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains; D012969:Sodium Fluoride / Q000494:pharmacology*; D013997:Time Factors
D011506:Proteins; D012969:Sodium Fluoride
Vplyv ftorydu natriiu na enerhetychnyĭ ta bilkovyĭ metabolizm u pechintsi shchuriv pislia ïï eksperimental'noï ishemiï.