[Current progress in cancer chemotherapy for childhood cancer].
New strategies in antineoplastic therapy that have been applied during the last 5 years to children with malignant disease include the Goldic-Coldman hypothesis, new methods of drug delivery, reduction in toxicity with prolonged intravenous infusions, shortening of maintenance therapy and techniques to improve the compliance of adolescents and older children with prescribed therapy. These new concepts of chemotherapy in developmental pharmacology to treat cancers in children are reviewed.
Fujimoto
T
T
Dept. of Pediatrics, Aichi Medical University, Japan.
D000818:Animals; D000970:Antineoplastic Agents / Q000493:pharmacokinetics / Q000627:therapeutic use*; D002648:Child; D002945:Cisplatin / Q000493:pharmacokinetics / Q000627:therapeutic use; D006801:Humans; D007939:Leukemia L1210 / Q000188:drug therapy; D009369:Neoplasms / Q000188:drug therapy* / Q000378:metabolism; D011379:Prognosis
D000970:Antineoplastic Agents; D002945:Cisplatin