Pancreatic polypeptide-immunoreactive gallbladder carcinoid tumor.
Gallbladder carcinoid tumor seen in a 62-year-old woman is described. The neoplasm with typical histologic features of classic carcinoid tumor was a 10 x 8 x 3 mm polyp at the neck of the gallbladder. The argyrophilic tumor cells were diffusely immunoreactive for neuron-specific enolase, cystatin C, chromogranin A and pancreatic polypeptide. A few cells were further positive for somatostatin. The presence of neurosecretory-type granules was confirmed ultrastructurally. The clinicopathologic significance of polypoid presentation of gallbladder carcinoid tumor is emphasized.
Tanaka
K
K
Department of Pathology, Tokai University School of Medicine, Isehara, Japan.
Iida
Y
Y
Tsutsumi
Y
Y
D002276:Carcinoid Tumor / Q000378:metabolism / Q000473:pathology*; D005260:Female; D005706:Gallbladder Neoplasms / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008854:Microscopy, Electron; D008875:Middle Aged; D010191:Pancreatic Polypeptide / Q000378:metabolism*
D010191:Pancreatic Polypeptide