title: Cone biopsy: a review of 112 cases.
abstract: A chart review of 112 patients who underwent cold knife conisation was performed. Records showed that 73.5% of the patients smoked cigarettes and 26.5% were using oral contraception. In 85.7% of cases pre-operative cytology/colposcopy findings were within one grade of the cone histology. The majority of lesions were CIN III (59.9%). Only 4.5% were normal. Human papilloma virus infection was detected histologically in 26.8% of patients. Pre-operative punch biopsy was undertaken in only five cases. Post-operative haemorrhage (9.0%) and genito-urinary infection (9.0%) were the main complications seen. The incidence of residual disease and post-cone hysterectomy was significantly higher if the margins of resection of the cone were unclear. Large-loop excision of the transformation zone (LLETZ) has now replaced cold knife conisation in both study centres due to its lower morbidity and reduced demand on hospital resources.
authors.affiliation: Department of Gynaecology, Rotunda Hospital.
authors.forename: E J
authors.initials: EJ
authors.lastname: Moore
authors.forename: C C
authors.initials: CC
authors.lastname: Fitzpatrick
authors.forename: B M
authors.initials: BM
authors.lastname: Coughlan
authors.forename: P J
authors.initials: PJ
authors.lastname: McKenna
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy / Q000379:methods; D002584:Cervix Uteri / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007494:Ireland; D008875:Middle Aged; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000517:prevention & control