Regional localization of human beta-casein gene (CSN2) to 4pter-q21.
Milk proteins are crucial for the development of all newborn mammals. Caseins that constitute the bulk of the protein in mammalian milk have been shown to be members of a multigene family in at least two species. They are among the most rapidly diverging groups of proteins, and their numbers vary widely among species. beta- and kappa-Caseins are the only caseins present in human milk. Using polymerase chain reaction on genomic DNA from somatic cell hybrids, we have localized the human beta-casein gene (CSN2) to 4pter----q21.
Menon
R S
RS
Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder 80309.
Chang
Y F
YF
Jeffers
K F
KF
Jones
C
C
Ham
R G
RG
D015139:Blotting, Southern; D002364:Caseins / Q000235:genetics*; D002894:Chromosomes, Human, Pair 4; D006801:Humans; D006822:Hybrid Cells; D005810:Multigene Family / Q000235:genetics*; D016133:Polymerase Chain Reaction
D002364:Caseins