title: Identification of a Saccharomyces cerevisiae homolog of the SNF2 transcriptional regulator in the DNA sequence of an 8.6 kb region in the LTE1-CYS1 interval on the left arm of chromosome I.
abstract: The DNA sequence of an 8.6 kb region of the left arm of chromosome I has been determined. This region, between the LTE1 and CYS1 loci, is approximately 40 kb from the centromere. There are six potential open-reading frames (ORFs), provisionally named YAL001-006 within this fragment of chromosome I. Four of these ORFs can be aligned with previously identified FUN transcripts: FUN28 with YAL006, FUN29 with YAL004, FUN30 with YAL001 and FUN31 with YAL002. The YAL001 ORF shows significant homology to the SNF2 transcriptional regulator. A region of the DNA contains an extensive repeat of the bases C-A-T positioned in the 5' terminus of the YAL004 promoter region.
authors.affiliation: Biology Department, McGill University, Montreal, Canada.
authors.forename: M W
authors.initials: MW
authors.lastname: Clark
authors.forename: W W
authors.initials: WW
authors.lastname: Zhong
authors.forename: T
authors.initials: T
authors.lastname: Keng
authors.forename: R K
authors.initials: RK
authors.lastname: Storms
authors.forename: A
authors.initials: A
authors.lastname: Barton
authors.forename: D B
authors.initials: DB
authors.lastname: Kaback
authors.forename: H
authors.initials: H
authors.lastname: Bussey
mesh_terms: D000251:Adenosine Triphosphatases; D001483:Base Sequence; D015825:Chromosomes, Fungal; D003001:Cloning, Molecular; D004271:DNA, Fungal / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics*; D015246:Deoxyribonuclease EcoRI; D005656:Fungal Proteins / Q000235:genetics*; D005800:Genes, Fungal; D008969:Molecular Sequence Data; D009687:Nuclear Proteins; D016366:Open Reading Frames; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D029701:Saccharomyces cerevisiae Proteins; D012689:Sequence Homology, Nucleic Acid; D014157:Transcription Factors / Q000235:genetics*
chemical_list: D004271:DNA, Fungal; D004268:DNA-Binding Proteins; C074000:FUN30 protein, S cerevisiae; D005656:Fungal Proteins; D009687:Nuclear Proteins; D029701:Saccharomyces cerevisiae Proteins; D014157:Transcription Factors; D015246:Deoxyribonuclease EcoRI; D000251:Adenosine Triphosphatases; C499333:SNF2 protein, S cerevisiae