Chlorella virus PBCV-1 replication is not affected by cytoskeletal disruptors.
The majority, if not the entire life cycle, of the large dsDNA-containing algal virus PBCV-1 occurs in localized regions in the cytoplasm. Thirteen drugs that disrupt the cytoskeleton had no effect on PBCV-1 replication at concentrations which inhibited host growth. Therefore, host cytoskeletal elements do not appear to be important in PBCV-1 morphogenesis.
Nietfeldt
J W
JW
Department of Plant Pathology, University of Nebraska, Lincoln 68583-0722.
Lee
K
K
Van Etten
J L
JL
D002708:Chlorella / Q000187:drug effects / Q000648:ultrastructure; D003599:Cytoskeleton / Q000187:drug effects*; D004267:DNA Viruses / Q000187:drug effects* / Q000502:physiology; D014779:Virus Replication / Q000187:drug effects*