title: Periosteum-wrapped alloplasts for reconstructive head and neck surgery.
abstract: Methylmethacrylate is widely used by orthopaedic and neurosurgeons for bone reconstruction. However, there is not much information about the interaction between methylmethacrylate and soft tissues. A prospective canine study was designed to examine the morphologic and histologic aspects of the use of methylmethacrylate with soft tissues. A previous study has shown that by wrapping the prosthesis with dense connective tissue, such as periosteum, better results can be achieved in tracheal reconstruction. Ten wrapped and 10 unwrapped pieces of methylmethacrylate were implanted in dogs, and were removed at intervals of 2, 4, 8, 11 and 16 weeks. Gross morphologic and histologic examination showed better incorporation of the wrapped implants into the surrounding soft tissues with less inflammation when compared to the unwrapped pieces. We suggest that connective tissue wrapped methylmethacrylate alloplasts are better tolerated by surrounding soft tissues and may lead to improved reconstructive results.
authors.affiliation: Department of Otolaryngology, Long Island College Hospital, New York.
authors.forename: G
authors.initials: G
authors.lastname: Har-El
authors.forename: M
authors.initials: M
authors.lastname: Nash
authors.forename: R B
authors.initials: RB
authors.lastname: Torno
authors.forename: M
authors.initials: M
authors.lastname: Goldsher
authors.forename: Y P
authors.initials: YP
authors.lastname: Krespi
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D004285:Dogs; D006084:Graft Rejection; D008768:Methylmethacrylates; D009132:Muscles / Q000473:pathology / Q000601:surgery*; D010521:Periosteum; D011183:Postoperative Complications / Q000209:etiology; D011446:Prospective Studies; D019736:Prostheses and Implants; D013997:Time Factors
chemical_list: D001672:Biocompatible Materials; D008768:Methylmethacrylates