Proliferative responses of lymphocytes to mitogens in the gray, short-tailed opossum, Monodelphis domestica.
A South American opossum (Monodelphis domestica) is a model animal for studies on the health effects of exposure to ultraviolet radiation (UVR). As part of a broad evaluation of immune function in this animal, we have tested in vitro mitogenic responses using whole blood cultures. Lymphocytes proliferated in the presence of phytohemagglutinin (PHA), concanavalin A (Con A), and pokeweed mitogen (PWM), but were unresponsive to bacterial lipopolysaccharide (LPS).
Brozek
C M
CM
Photomedicine Program, Lovelace Medical Foundation, Albuquerque, NM 87108.
Kaleta
E W
EW
Kusewitt
D F
DF
Ley
R D
RD
D000818:Animals; D008213:Lymphocyte Activation / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology; D008934:Mitogens / Q000276:immunology*; D009893:Opossums / Q000276:immunology*
D008934:Mitogens