Impact of schistosomiasis on urinary bladder cancer in the southern province of Saudi Arabia: review of 60 cases.
The histopathologic findings reported in 254 consecutive urinary bladder biopsies were reviewed. Evidence of urinary schistosomiasis was identified in 88 biopsies (35%) and malignant neoplasms were diagnosed in 60 cases (24%). Nine out of 60 (15%) cases of bladder cancer had urinary bladder schistosomiasis and the remaining 51 cases (85%) had no clinical evidence of schistosomiasis. Transitional cell carcinoma was the commonest type of urinary bladder cancer (70%) followed by squamous cell carcinoma (20%) adenocarcinoma (8%) and rhabdomyosarcoma (2%). The mean age of the patients included was 60 +/- 15 years and the male:female ratio was 9:1. Comparison of our findings to those reported from other provinces of Saudi Arabia and from other countries, including those with known high incidence of schistosomiasis, is included.
Khurana
P
P
Department of Pathology, Asir Central Hospital, Abha, Saudi Arabia.
Morad
N
N
Khan
A R
AR
Shetty
S
S
Ibrahim
A
A
Patil
K
K
D000230:Adenocarcinoma / Q000150:complications / Q000453:epidemiology; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000453:epidemiology; D002295:Carcinoma, Transitional Cell / Q000150:complications / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012529:Saudi Arabia / Q000453:epidemiology; D012553:Schistosomiasis haematobia / Q000150:complications* / Q000453:epidemiology; D001749:Urinary Bladder Neoplasms / Q000150:complications* / Q000453:epidemiology