On the question of RBE reversal at high doses.
We present theoretical arguments to explain observations of a "reversal" of the RBE at relatively large doses; that is, the RBE of high-LET vs low-LET radiation is less than one. Numerical examples are given and the results of Bogo et al. (Radiat. Res. 118, 341-352, 1989) are discussed qualitatively.
Zaider
M
M
Center for Radiological Research of Columbia University, New York, New York 10032.
Rossi
H H
HH
D004307:Dose-Response Relationship, Radiation; D008962:Models, Theoretical; D012062:Relative Biological Effectiveness