title: Antimicrobial properties of secretions from the metapleural glands of Myrmecia gulosa (the Australian bull ant).
abstract: Myrmecia gulosa (Australian bull ant) produce secretions from their metapleural exocrine glands which have broad spectrum antimicrobial properties. Such secretions are probably of importance in disease control in bull ant communities. These antimicrobial secretions are stable at 100 degrees C, resistant to proteolytic enzymes and are active over a wide pH range. Of the organisms tested only endospores of Bacillus cereus were found to be resistant. The antimicrobial agent(s) are absorbed by cells and result in cell lysis. The secretions do not interfere with any growth-related processes. These observations demonstrate that insects may be a source of novel antimicrobial agent(s).
authors.affiliation: School of Biological Sciences, Macquarie University, New South Wales, Australia.
authors.forename: D A
authors.initials: DA
authors.lastname: Veal
authors.forename: J E
authors.initials: JE
authors.lastname: Trimble
authors.forename: A J
authors.initials: AJ
authors.lastname: Beattie
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D001000:Ants / Q000378:metabolism*; D002175:Candida / Q000187:drug effects* / Q000254:growth & development; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects*; D006863:Hydrogen-Ion Concentration; D013696:Temperature
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents