Effect of acute alcohol ingestion on short-term heart rate fluctuations.
Acute ingestion of a low dose of alcohol (0.3 g/Kg) in a group of 18 healthy volunteers does not alter RR mean nor RR variance, producing only a slight decrease in the heart rate variability (HRV) measured by the mean momentary arrhythmia. However, power spectral of the HRV signal shows appreciable changes in the magnitude of the short-term RR fluctuations. Low frequency RR oscillations (0.02-0.06 Hz) increase in power during the 20-45 min. period after alcohol intake, while middle (0.08-0.15 Hz) frequency oscillations decrease in power during the 20-60 min. period and higher (0.20-0.35 Hz) frequency oscillations decrease in power during the 5-60 min. period after intake. The most drastic changes were observed in the middle frequency oscillations during the 20-30 min. period after intake while higher frequency oscillations seem to be less affected by the alcohol ingestion.
Gonzalez Gonzalez
J
J
Departamento de Fisiología, Facultad de Medicina, Universidad de La Laguna, Tenerife, Spain.
Mendez Llorens
A
A
Mendez Novoa
A
A
Cordero Valeriano
J J
JJ
D000328:Adult; D000428:Alcohol Drinking / Q000503:physiopathology*; D000435:Alcoholic Intoxication / Q000503:physiopathology*; D004305:Dose-Response Relationship, Drug; D004562:Electrocardiography / Q000187:drug effects* / Q000295:instrumentation; D000431:Ethanol / Q000493:pharmacokinetics; D006339:Heart Rate / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D008297:Male; D008838:Microcomputers; D010275:Parasympathetic Nervous System / Q000187:drug effects / Q000503:physiopathology; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation; D013564:Sympathetic Nervous System / Q000187:drug effects / Q000503:physiopathology
D000431:Ethanol