title: Enterocytozoon bieneusi infection in acquired immunodeficiency syndrome-related sclerosing cholangitis.
abstract: Acalculous cholecystitis and sclerosing cholangitis due to Cryptosporidium sp, and cytomegalovirus have been described in patients with the acquired immunodeficiency syndrome (AIDS). However, in about 40% of cases of AIDS-related biliary disease, no opportunistic pathogen is identified. The current case report describes the first case, to the best of the authors' knowledge, of AIDS-related sclerosing cholangitis associated with microsporidiosis. Enterocytozoon bieneusi was detected in the duodenum and bile by means of light microscopy and confirmed by electron microscopy. Microsporidian infection should be suspected in patients with AIDS-related sclerosing cholangitis as well as in cases of diarrhea in which none of the usual pathogens are found.
authors.affiliation: Unité d'Hépatologie, Hôpital Laënnec, Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Pol
authors.forename: C
authors.initials: C
authors.lastname: Romana
authors.forename: S
authors.initials: S
authors.lastname: Richard
authors.forename: F
authors.initials: F
authors.lastname: Carnot
authors.forename: J L
authors.initials: JL
authors.lastname: Dumont
authors.forename: H
authors.initials: H
authors.lastname: Bouche
authors.forename: G
authors.initials: G
authors.lastname: Pialoux
authors.forename: M
authors.initials: M
authors.lastname: Stern
authors.forename: J F
authors.initials: JF
authors.lastname: Pays
authors.forename: P
authors.initials: P
authors.lastname: Berthelot
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D015209:Cholangitis, Sclerosing / Q000209:etiology*; D006801:Humans; D008297:Male; D016881:Microsporidiosis / Q000150:complications*; D009894:Opportunistic Infections / Q000150:complications