The brain-gut axis: a model system to study gene regulation.
The data summarized show unequivocal differences in gene regulation between the brain and the intestine in the rat. It is possible that the differences may occur partly as a reflection of cell turnover kinetics. The mechanisms accounting for these differences should provide fertile ground for investigation. I conclude that the brain-gut axis provides a model for studying differential gene regulation in animals.
Greenstein
R J
RJ
Dept. of Surgery, Veterans Affairs Medical Center, Bronx, NY 10468.
D000818:Animals; D001921:Brain / Q000378:metabolism*; D002766:Cholecystokinin / Q000235:genetics*; D005786:Gene Expression Regulation; D007413:Intestinal Mucosa / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism; D051381:Rats
D012333:RNA, Messenger; D002766:Cholecystokinin