The GI T-lymphocyte theory of schizophrenia: some new observations.
Schizophrenic patients have low concentrations of PGE-1, n-6 fatty acids, vitamin C and zinc, elevated brain levels of dopamine and high plasma levels of interleukin-2 receptors (IL-2R). IL-2R plasma titers can be raised in celiac patients by administering wheat. These findings are both consistent with and supportive of the GI T-lymphocyte theory of schizophrenia.
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D001206:Ascorbic Acid Deficiency / Q000150:complications; D004064:Digestive System / Q000276:immunology; D005231:Fatty Acids, Unsaturated / Q000378:metabolism; D006801:Humans; D007376:Interleukin-2 / Q000096:biosynthesis; D008954:Models, Biological; D011458:Prostaglandins E / Q000172:deficiency; D012559:Schizophrenia / Q000209:etiology* / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D014908:Triticum / Q000009:adverse effects; D015032:Zinc / Q000172:deficiency
D005231:Fatty Acids, Unsaturated; D007376:Interleukin-2; D011458:Prostaglandins E; D015032:Zinc