title: [Lipid metabolism in the cells of the intestinal mucosa in the early and late periods after gamma irradiation in rats].
abstract: Two hours following 20 Gy irradiation of rats cholesterol synthesis in crypt cells was activated, and 24 h after 4 Gy irradiation it was inhibited in crypt cells and activated in villus cells. Remote effects of fractionated irradiation (6 Gy) on lipid metabolism in the intestinal cells were observed during a period of six months following irradiation. Cholesterol and phospholipid synthesis activation in crypt cells was observed during the first months following irradiation, and in villus cells after 3 and 6 months, whereas the phospholipid synthesis in these cells was inhibited throughout the entire period of observation.
authors.forename: E G
authors.initials: EG
authors.lastname: Novoselova
mesh_terms: D000818:Animals; D002250:Carbon Radioisotopes; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D007413:Intestinal Mucosa / Q000166:cytology / Q000378:metabolism / Q000528:radiation effects*; D050356:Lipid Metabolism; D008055:Lipids / Q000528:radiation effects*; D008297:Male; D011833:Radiation Injuries, Experimental / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
chemical_list: D002250:Carbon Radioisotopes; D008055:Lipids
vernacular_title: Lipidnyĭ obmen v kletkakh slizistoĭ kishechnika v rannie i otdalennye sroki posle gamma-obluchenii krys.