title: Molecular diagnosis of Ureaplasma urealyticum septic arthritis in a patient with hypogammaglobulinemia.
abstract: OBJECTIVE
  We report a hypogammaglobulinemic patient with a destructive oligoarticular arthritis, whose synovial fluid cultures were repeatedly sterile.
  
  
  RESULTS
  We identified a Ureaplasma urealyticum infection in his affected joints, using a polymerase chain reaction (PCR) assay.
  
  
  CONCLUSIONS
  The PCR technique promises to be extremely valuable in the rapid and specific diagnosis of infectious arthritis.
authors.affiliation: Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia.
authors.forename: A H
authors.initials: AH
authors.lastname: Lee
authors.forename: T
authors.initials: T
authors.lastname: Ramanujam
authors.forename: P
authors.initials: P
authors.lastname: Ware
authors.forename: P H
authors.initials: PH
authors.lastname: Edelstein
authors.forename: J J
authors.initials: JJ
authors.lastname: Brooks
authors.forename: B
authors.initials: B
authors.lastname: Freundlich
authors.forename: H R
authors.initials: HR
authors.lastname: Schumacher
authors.forename: R B
authors.initials: RB
authors.lastname: Zurier
authors.forename: D B
authors.initials: DB
authors.lastname: Weiner
authors.forename: W V
authors.initials: WV
authors.lastname: Williams
mesh_terms: D000328:Adult; D000361:Agammaglobulinemia / Q000150:complications*; D001170:Arthritis, Infectious / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism; D001483:Base Sequence; D004269:DNA, Bacterial / Q000032:analysis*; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011948:Receptors, Antigen, T-Cell / Q000235:genetics / Q000378:metabolism; D013583:Synovial Membrane / Q000378:metabolism; D016869:Ureaplasma Infections / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism; D016990:Ureaplasma urealyticum / Q000235:genetics
chemical_list: D004269:DNA, Bacterial; D011948:Receptors, Antigen, T-Cell