title: Intracerebral thrombosis. Case report and brief clinical review.
abstract: A 29-yr-old writer presented with seizures and left hemiparesis 8 days post-partum. Studies revealed right parietal hemorrhagic infarction secondary to superior sagittal sinus thrombosis. An anticoagulant was given for clot extension associated with increasing cerebral edema and coma. Inpatient rehabilitation was undertaken for residual left hemiparesis, most severe in the leg. Left arm strength rapidly returned to normal. Significant improvement in left leg strength occurred but was delayed for many months. Intracerebral thrombosis is an uncommon but significant cause of stroke in young adults. It frequently occurs in the puerperium and may be associated with unilateral or bilateral neurologic deficits. Treatment with anticoagulants is controversial because of the risk of hemorrhagic cerebral infarction, but may be beneficial in some cases. Recovery may be delayed for several months pending recanalization of the sinus or the development of collateral circulation. The overall prognosis for neurologic and functional recovery in survivors of intracerebral thrombosis is good.
authors.affiliation: Department of Clinical Epidemiology and Preventive Medicine, University of Pittsburgh School of Medicine, Pennsylvania.
authors.forename: E B
authors.initials: EB
authors.lastname: Scott
mesh_terms: D000328:Adult; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000209:etiology / Q000534:rehabilitation*; D011644:Puerperal Disorders / Q000534:rehabilitation*; D013927:Thrombosis / Q000150:complications / Q000188:drug therapy; D016306:Vena Cava Filters; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D014859:Warfarin; D006493:Heparin