title: Chromosome size-dependent control of meiotic recombination.
abstract: Smaller chromosomes have higher rates of meiotic reciprocal recombination (centimorgans per kilobase pair) than larger chromosomes. This report demonstrates that decreasing the size of Saccharomyces cerevisiae chromosomal DNA molecules increases rates of meiotic recombination and increasing chromosome size decreases recombination rates. These results indicate that chromosome size directly affects meiotic reciprocal recombination.
authors.affiliation: Department of Microbiology and Molecular Genetics, Graduate School of Biomedical Sciences, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark 07103.
authors.forename: D B
authors.initials: DB
authors.lastname: Kaback
authors.forename: V
authors.initials: V
authors.lastname: Guacci
authors.forename: D
authors.initials: D
authors.lastname: Barber
authors.forename: J W
authors.initials: JW
authors.lastname: Mahon
mesh_terms: D002874:Chromosome Mapping; D015825:Chromosomes, Fungal / Q000502:physiology*; D004271:DNA, Fungal / Q000235:genetics; D005785:Gene Conversion; D005800:Genes, Fungal; D006720:Homozygote; D007621:Karyotyping; D008540:Meiosis / Q000235:genetics*; D011995:Recombination, Genetic; D012441:Saccharomyces cerevisiae / Q000166:cytology / Q000235:genetics*; D014178:Translocation, Genetic
chemical_list: D004271:DNA, Fungal