Role of electric stimulation in bladder evacuation following spinal cord transection.
Neural stimulation is potentially a valuable therapeutic tool in the treatment of neurogenic bladder with detrusor areflexia. We studied 20 dogs in different groups, up to eight months, and compared the effect of electric stimulation with intermittent catheterization, specially during spinal shock phase. We found that early stimulation hastened the return of detrusor activity. When stimulation was delayed, the bladder could still regain its activity, and when the pace-maker was turned off, the detrusor activity was gradually decreased. Neurostimulation can completely empty bladder up to eight months. The lowest A.Ch. content in detrusor muscle was found in intermittent catheterization group and in this group the detrusor strips showed marked supersensitivity to urecholine stimulation than the bladders managed by electric stimulation. Also, we found that electric stimulation reduced the complications caused by intermittent catheterization and protected kidney function.
Li
J S
JS
Urology Research Laboratory, Royal Victorial Hospital, McGill University, Montreal, Quebec, Canada.
Hassouna
M
M
Sawan
M
M
Duval
F
F
Latt
R
R
Carter
K
K
Collier
B
B
Elhilali
M M
MM
D000818:Animals; D004285:Dogs; D004558:Electric Stimulation; D015994:Incidence; D007677:Kidney Function Tests; D008297:Male; D013116:Spinal Cord / Q000601:surgery; D001743:Urinary Bladder / Q000502:physiology*; D014546:Urinary Catheterization / Q000009:adverse effects; D014552:Urinary Tract Infections / Q000453:epidemiology / Q000209:etiology; D014554:Urination / Q000502:physiology*; D014563:Urodynamics