[Calcium metabolism and the diastolic rigidity status of the myocardium in patients with ischemic heart disease under the influence of calcium antagonist treatment].
The calcium (Ca2+) metabolism disorder in IHD patients which manifests itself in an increase of blood serum content of ionized Ca2+ and its accumulation in red blood cells and in cardiomyocytes is accompanied by myocardial functional disturbances as an increase in myocardial stiffness. The increase both of ionized Ca2+ content in blood plasma and left ventricular rigidity are prerequisites for the antianginal effect of corinfar. Normalization of Ca2+ content in blood plasma by corinfar can serve as a criterion of therapy efficiency of IHD patients.
Lomakovs'kyĭ
O M
OM
Mkhytarian
L S
LS
D002118:Calcium / Q000097:blood*; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D003327:Coronary Disease / Q000097:blood* / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D003971:Diastole / Q000187:drug effects* / Q000502:physiology; D006352:Heart Ventricles / Q000187:drug effects / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D009543:Nifedipine / Q000627:therapeutic use
D002121:Calcium Channel Blockers; D009543:Nifedipine; D002118:Calcium
Kal'tsiievyĭ obmin i stan diastolichnoï zhorstkosti miokardu u khvorykh na ishemichnu khvorobu sertsia pid vplyvom likuvannia antahonistamy kal'tsiiu.