title: Aerosolized vancomycin therapy facilitating nursing home placement.
abstract: OBJECTIVE
  To demonstrate a novel method of eliminating nasopharyngeal colonization by methicillin-resistant Staphylococcus aureus (MRSA) in a debilitated, hospitalized patient.
  
  
  METHODS
  Single-patient, nonblind, nonplacebo, case study.
  
  
  METHODS
  Community hospital, Brooklyn, NY.
  
  
  METHODS
  Hospitalized patient with recalcitrant nasopharyngeal MRSA colonization that could not be eliminated by conventional therapeutic interventions.
  
  
  METHODS
  Aerosolized vancomycin hydrochloride 120 mg q6h administered in room air via face mask together with vancomycin nasal drops, 2 drops to each nostril q6h.
  
  
  METHODS
  Elimination of MRSA from the nasopharynx of the patient.
  
  
  RESULTS
  Successful elimination of MRSA colonization after four days of therapy.
  
  
  CONCLUSIONS
  Aerosolized vancomycin in combination with vancomycin nasal drops is beneficial in eliminating nasopharyngeal colonization by MRSA. Clinical trials are warranted to confirm this clinical observation.
authors.affiliation: Division of Infectious Diseases, Maimonides Medical Center, Brooklyn.
authors.forename: J D
authors.initials: JD
authors.lastname: Gradon
authors.forename: E H
authors.initials: EH
authors.lastname: Wu
authors.forename: L I
authors.initials: LI
authors.lastname: Lutwick
mesh_terms: D000280:Administration, Inhalation; D000368:Aged; D000369:Aged, 80 and over; D002353:Carrier State / Q000188:drug therapy* / Q000382:microbiology; D006764:Hospitals, Community; D006801:Humans; D008297:Male; D016106:Methicillin Resistance; D009305:Nasopharynx / Q000382:microbiology*; D009735:Nursing Homes; D010360:Patient Transfer; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects*; D014640:Vancomycin / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D014640:Vancomycin