title: Hepatic perfusion index: a multicentre trial.
abstract: The reproducibility and accuracy of the hepatic perfusion index (HPI) was examined by consideration of in vitro and in vivo factors. A phantom was used to simulate liver blood flow and data acquired on nine gamma cameras. Dynamic hepatic scintigraphy was undertaken on 28 patients at two centres and values obtained for the HPI. Results from the phantom study showed good agreement between the nine cameras and also with the HPI values predicted from the measured phantom flow rates. The results of the patient study indicated a high degree of conformity between observers (r = 0.95, S.E = 0.03) but poorer correlation between the HPI values from the two centres (r = 0.67, S.E. = 0.09). These results imply that centres wishing to use HPI clinically should establish their own range of normality.
authors.affiliation: Department of Medical Physics, St James's University Hospital, Leeds, UK.
authors.forename: J
authors.initials: J
authors.lastname: Maughan
authors.forename: A
authors.initials: A
authors.lastname: Parkin
authors.forename: A H
authors.initials: AH
authors.lastname: Smith
authors.forename: M C
authors.initials: MC
authors.lastname: Barker
authors.forename: P J
authors.initials: PJ
authors.lastname: Robinson
authors.forename: P
authors.initials: P
authors.lastname: Finan
authors.forename: P
authors.initials: P
authors.lastname: Gilson
authors.forename: M
authors.initials: M
authors.lastname: Avison
mesh_terms: D001783:Blood Flow Velocity; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D066298:In Vitro Techniques; D008102:Liver Circulation; D008961:Models, Structural; D015588:Observer Variation; D011877:Radionuclide Imaging; D015203:Reproducibility of Results; D013671:Technetium Tc 99m Sulfur Colloid
chemical_list: D013671:Technetium Tc 99m Sulfur Colloid