title: Sex but no hand difference in the isthmus of the corpus callosum.
abstract: We performed high-resolution magnetic resonance morphometry of the total midsagittal area and seven midsagittal subareas of the corpus callosum in healthy young adult dextrals and sinistrals (N = 52). There was no influence of handedness on these anatomic measurements. However, an effect of sex emerged, with women (N = 26) having a larger proportional isthmus segment of the callosum. This may reflect a sex-specific difference in the interhemispheric connectivity and functional organization of the temporoparietal association cortex.
authors.affiliation: Department of Neurology, Heinrich-Heine University, Düsseldorf, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Steinmetz
authors.forename: L
authors.initials: L
authors.lastname: Jäncke
authors.forename: A
authors.initials: A
authors.lastname: Kleinschmidt
authors.forename: G
authors.initials: G
authors.lastname: Schlaug
authors.forename: J
authors.initials: J
authors.lastname: Volkmann
authors.forename: Y
authors.initials: Y
authors.lastname: Huang
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D003337:Corpus Callosum / Q000033:anatomy & histology / Q000502:physiology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D015999:Multivariate Analysis; D012727:Sex Characteristics