Granulocytic sarcoma with meningeal leukemia but no bone marrow involvement at presentation. A report of two cases with characteristic cerebrospinal fluid cytology.
Two cases occurred of granulocytic sarcoma with cerebrospinal fluid involvement but no associated leukemia on presentation. Both cases were difficult to identify by histology and were initially misdiagnosed as malignant lymphoma. The characteristic cerebrospinal fluid cytologic picture allowed the diagnosis. These cases underscore the value of cytologic examination of tumor imprints and the use of myeloid markers in panels for immunophenotyping lymphomas.
Lagrange
M
M
Department of Hematology-Oncology, Centre Antoine Lacassagne, Nice, France.
Gaspard
M H
MH
Lagrange
J L
JL
Michiels
J F
JF
Hofman
P
P
Thyss
A
A
Schneider
M
M
D000328:Adult; D001856:Bone Marrow Examination; D006801:Humans; D007951:Leukemia, Myeloid / Q000134:cerebrospinal fluid* / Q000473:pathology; D015470:Leukemia, Myeloid, Acute / Q000134:cerebrospinal fluid* / Q000473:pathology; D008297:Male; D008578:Meninges / Q000473:pathology*