Nasal polyps, bronchial asthma and aspirin sensitivity.
The ASA triad comprises bronchial asthma, acetylsalicylic acid (ASA) sensitivity and nasal polyps. It presents as chronic rhinitis followed by bronchial asthma and ASA sensitivity, and later nasal polyps. The pathogenesis of the ASA triad may involve interrelationships between disease in the upper and lower airway and hypersensitivity to cyclo-oxygenase inhibiting medications. Treatment of the nasal polyps has been shown to improve the patients' asthma.
Probst
L
L
Department of Otolaryngology, St. Joseph's Health Centre, Toronto, Ontario, Canada.
Stoney
P
P
Jeney
E
E
Hawke
M
M
D001241:Aspirin / Q000009:adverse effects*; D001249:Asthma / Q000150:complications*; D004342:Drug Hypersensitivity / Q000150:complications*; D006801:Humans; D009298:Nasal Polyps / Q000150:complications*; D012220:Rhinitis / Q000150:complications; D013577:Syndrome
D001241:Aspirin