title: Raised intracranial pressure and visual complications in AIDS patients with cryptococcal meningitis.
abstract: The clinical course of cryptococcal meningitis in AIDS shows some important differences from the features of the illness in non-AIDS patients. Complications such as raised intracranial pressure and visual impairment that are recognised in non-AIDS patients may be less frequent in those with AIDS. Persistent intracranial hypertension should be managed actively to prevent visual impairment. In AIDS patients, in whom ventriculo-peritoneal shunts carry additional risks, acetazolamide can be used successfully to lower the CSF pressure and prevent visual loss.
authors.affiliation: Infectious Diseases Unit, Royal Postgraduate Medical School, Hammersmith Hospital, London, U.K.
authors.forename: S R
authors.initials: SR
authors.lastname: Johnston
authors.forename: E L
authors.initials: EL
authors.lastname: Corbett
authors.forename: O
authors.initials: O
authors.lastname: Foster
authors.forename: S
authors.initials: S
authors.lastname: Ash
authors.forename: J
authors.initials: J
authors.lastname: Cohen
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D001766:Blindness / Q000209:etiology; D003389:Cranial Nerve Diseases / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D003455:Cryptococcus neoformans; D005260:Female; D005437:Flucytosine / Q000627:therapeutic use; D006801:Humans; D007427:Intracranial Pressure; D008297:Male; D016919:Meningitis, Cryptococcal / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D008875:Middle Aged; D010211:Papilledema / Q000150:complications; D014454:Uganda / Q000208:ethnology
chemical_list: D000666:Amphotericin B; D005437:Flucytosine