title: Epidemiologic and serologic definition of primary and secondary trichinosis in the Arctic.
abstract: A large outbreak of trichinosis acquired from walrus in Salluit in 1987 provided the immunologic and epidemiologic data from which two distinct clinical syndromes were identified. The first syndrome is the classic myopathic form with edema, fever, myalgia, and rash. The second is a persistent diarrheal illness with little edema or myalgia. The clinical presentations are paralleled by distinct differences in type and development of antibody response. The clinical and serologic profiles of the two syndromes support the hypothesis that the myopathic form represents a primary infection of Trichinella nativa, while the second represents a secondary infection in previously sensitized individuals.
authors.affiliation: Department of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada.
authors.forename: J D
authors.initials: JD
authors.lastname: MacLean
authors.forename: L
authors.initials: L
authors.lastname: Poirier
authors.forename: T W
authors.initials: TW
authors.lastname: Gyorkos
authors.forename: J F
authors.initials: JF
authors.lastname: Proulx
authors.forename: J
authors.initials: J
authors.lastname: Bourgeault
authors.forename: A
authors.initials: A
authors.lastname: Corriveau
authors.forename: S
authors.initials: S
authors.lastname: Illisituk
authors.forename: M
authors.initials: M
authors.lastname: Staudt
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood*; D001110:Arctic Regions; D002648:Child; D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology / Q000209:etiology / Q000276:immunology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007223:Infant; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000453:epidemiology / Q000209:etiology / Q000276:immunology; D014234:Trichinella / Q000276:immunology*; D014235:Trichinellosis / Q000453:epidemiology* / Q000209:etiology / Q000276:immunology; D014856:Walruses / Q000469:parasitology*
chemical_list: D000909:Antibodies, Helminth; D007074:Immunoglobulin G