title: Epidermolysis bullosa acquisita, a rare late complication of allogeneic bone marrow transplantation?
abstract: We report a rare disease of skin and oropharyngeal mucosa in a 28-year-old patient occurring 2 years after an allogeneic bone marrow transplantation. The dermatologic diagnosis was unambiguously epidermolysis bullosa acquisita according to the immunofluorescence and clinical presentation. Treatment with cyclosporin A and prednisone resulted in resolution. This autoimmune skin disease may be a manifestation of graft-versus-host disease, but the relationship must remain speculative.
authors.affiliation: Medizinische Klinik, Universitätsspital Zürich, Switzerland.
authors.forename: J
authors.initials: J
authors.lastname: Burger
authors.forename: J
authors.initials: J
authors.lastname: Gmür
authors.forename: L
authors.initials: L
authors.lastname: Bruckner-Tuderman
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001327:Autoimmune Diseases / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D016026:Bone Marrow Transplantation / Q000009:adverse effects; D003131:Combined Modality Therapy; D016572:Cyclosporine / Q000627:therapeutic use; D016107:Epidermolysis Bullosa Acquisita / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D006086:Graft vs Host Disease / Q000150:complications*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy / Q000628:therapy; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D012074:Remission Induction; D014184:Transplantation, Homologous
chemical_list: D016572:Cyclosporine; D011241:Prednisone