Detection of estradiol-induced messenger RNA (pS2) in uninvolved breast tissue from mastectomies for breast cancer.
pS2 mRNA was estimated in uninvolved breast tissue and breast carcinoma from the same patients. pS2 mRNA was clearly detected in 14 of 59 uninvolved breast tissues and in 30 of 58 breast carcinomas. pS2 mRNA was found more frequently in uninvolved breast tissue of premenopausal women than in that of postmenopausal women.
Hähnel
E
E
Department of Pathology, University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands.
Joyce
R
R
Sterrett
G
G
Harvey
J
J
Hähnel
R
R
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001940:Breast / Q000737:chemistry* / Q000502:physiology; D001943:Breast Neoplasms / Q000737:chemistry* / Q000235:genetics / Q000473:pathology; D004958:Estradiol / Q000494:pharmacology*; D005260:Female; D015870:Gene Expression / Q000187:drug effects / Q000235:genetics; D006801:Humans; D008408:Mastectomy; D008593:Menopause / Q000502:physiology; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000235:genetics*; D011506:Proteins; D012333:RNA, Messenger / Q000032:analysis* / Q000187:drug effects / Q000235:genetics; D000071163:Trefoil Factor-1; D025521:Tumor Suppressor Proteins
D009363:Neoplasm Proteins; D011506:Proteins; D012333:RNA, Messenger; C051838:TFF1 protein, human; D000071163:Trefoil Factor-1; D025521:Tumor Suppressor Proteins; D004958:Estradiol