title: Fulminant hepatic failure related to omeprazole.
abstract: Omeprazole is a new hydrogen-potassium adenosine triphosphatase antagonist with indications for severe reflux esophagitis and Zollinger-Ellison syndrome. Side effects involving the liver have consisted of minimal elevations of hepatocellular enzymes with higher dosages. We present what we believe is the first reported case of fulminant hepatic failure related to omeprazole.
authors.affiliation: Department of Gastroenterology, Ohio State University, Columbus.
authors.forename: V
authors.initials: V
authors.lastname: Jochem
authors.forename: R
authors.initials: R
authors.lastname: Kirkpatrick
authors.forename: J
authors.initials: J
authors.lastname: Greenson
authors.forename: M
authors.initials: M
authors.lastname: Brogan
authors.forename: T
authors.initials: T
authors.lastname: Sturgis
authors.forename: C
authors.initials: C
authors.lastname: Cook-Glenn
mesh_terms: D004942:Esophagitis, Peptic / Q000188:drug therapy; D006501:Hepatic Encephalopathy / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009853:Omeprazole / Q000009:adverse effects*
chemical_list: D009853:Omeprazole