Use of cultured epidermal autograft in ten patients.
This article updates our single-center experience, which was reported in 1990 (Munster AM, Weiner S, Spence RB. Cultured epidermis for the coverage of massive burns: a single center experience. Ann Surg 1990;211:676-80). Current data include data from the time period 1988 to 1990. To date, 10 patients with a mean surface burn of 71.6% were partially treated with cultured epidermal autograft, and no deaths occurred. A group of 41 control patients (partly retrospective and partly concurrent but not randomized) sustained a mean burn of 54.7% body surface area. There were 14 deaths (p less than 0.05 versus the group that received cultured epidermal autograft). No major problems with late graft fragility (up to 2 years) or contracture were noted.
Munster
A M
AM
Johns Hopkins University School of Medicine, Baltimore, Maryland.
D000328:Adult; D015142:Baltimore; D002053:Burn Units; D002056:Burns / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002478:Cells, Cultured; D000078404:Epidermal Cells; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D012189:Retrospective Studies; D016038:Skin Transplantation / Q000379:methods*; D014182:Transplantation, Autologous