Hemodynamics and metabolism in ischemic cerebrovascular disease.
Measurements of CBF and CMR in human ischemia and infarction have provided valuable insight into the pathophysiology of stroke and important guidance to the development of therapeutic strategies. Further research combing therapeutic manipulation with CBF and CMR will be important for developing optimal methods to treat ischemic cerebrovascular disease. At this time, no value has been demonstrated for these techniques in individual patient care decisions. Although now widely available, CBF and CMR measurements should still be considered clinical research tools until they can be shown to provide benefit in reducing morbidity and mortality or reducing medical expenses in clinical practice.
Powers
W J
WJ
Department of Neurology, Washington University School of Medicine, St. Louis, Missouri.
D002545:Brain Ischemia / Q000175:diagnosis / Q000503:physiopathology*; D002544:Cerebral Infarction / Q000503:physiopathology; D002560:Cerebrovascular Circulation / Q000502:physiology; D004734:Energy Metabolism / Q000502:physiology*; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D012016:Reference Values; D014055:Tomography, Emission-Computed