[The adrenergic and dopaminergic regulation of kidney acid-excreting function].
It has been found in experiments on white rats that the activation of peripheral alpha 1-adrenoreceptors and dopamine receptors of type I stimulates acid-excretory renal function with inhibition of the angiotensin-aldosterone system. The blockade of alpha 1-adreno- and dopamine receptors depresses acid-excretory renal activity. The activation and inhibition of beta-adrenoreceptors do not change the excretion of hydrogen ions. The role of the activation of peripheral alpha 1-adreno- and dopamine receptors in compensatory reactions of the organism at metabolic acidosis is discussed.
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D000818:Animals; D004231:Diuresis / Q000187:drug effects; D007668:Kidney / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D051381:Rats; D011941:Receptors, Adrenergic / Q000187:drug effects / Q000502:physiology*; D011954:Receptors, Dopamine / Q000187:drug effects / Q000502:physiology*; D012083:Renin / Q000097:blood / Q000187:drug effects; D012084:Renin-Angiotensin System / Q000187:drug effects; D013565:Sympatholytics / Q000494:pharmacology; D013566:Sympathomimetics / Q000494:pharmacology
D011941:Receptors, Adrenergic; D011954:Receptors, Dopamine; D013565:Sympatholytics; D013566:Sympathomimetics; D012083:Renin
Adrenergicheskaia i dofaminergicheskaia reguliatsiia kislotovydelitel'noĭ funktsii pochek.