title: Antibiotic-associated neutropenia.
abstract: Neutropenia is an uncommon but potentially serious complication of drug therapy. Many drugs, especially antibiotics, can produce this untoward effect. Typically, drug-induced neutropenia occurs in a patient receiving a semisynthetic penicillin for two weeks or more. The cause is believed to be either a hypersensitivity reaction or a toxic dose-related suppression of white blood cell precursors. Most patients improve after discontinuation of the drug.
authors.affiliation: Wright State University School of Medicine, Dayton, Ohio.
authors.forename: G S
authors.initials: GS
authors.lastname: Walbroehl
authors.forename: P G
authors.initials: PG
authors.lastname: John
mesh_terms: D001168:Arthritis / Q000188:drug therapy; D002648:Child; D006801:Humans; D007719:Knee Joint; D007958:Leukocyte Count / Q000187:drug effects; D008297:Male; D009254:Nafcillin / Q000009:adverse effects*; D009503:Neutropenia / Q000139:chemically induced*; D009504:Neutrophils; D013203:Staphylococcal Infections / Q000188:drug therapy; D013290:Streptococcal Infections / Q000188:drug therapy
chemical_list: D009254:Nafcillin