A malaria vaccine strategy based on the induction of cellular immunity.
In this article, Michael Good offers an alternative to the current emphasis on developing subunit, humoral-response-inducing malaria vaccines. He develops a three-pronged proposal comprising (1) a greater emphasis on cellular immunity, (2) analysis of the role of the spleen in protection, and (3) the development of an attenuated vaccine.
Good
M F
MF
Queensland Institute of Medical Research, Bancroft Centre, Brisbane, Australia.
D000818:Animals; D006801:Humans; D007111:Immunity, Cellular; D008288:Malaria / Q000276:immunology / Q000517:prevention & control*; D010961:Plasmodium / Q000276:immunology; D016052:Protozoan Vaccines; D014612:Vaccines; D014613:Vaccines, Attenuated / Q000276:immunology
D016052:Protozoan Vaccines; D014612:Vaccines; D014613:Vaccines, Attenuated