title: Platelet catecholamines in cluster headache.
abstract: Platelet tyrosine and catecholamine (CA) content was measured in cluster headache sufferers during the different phases of the illness. Compared with controls, cluster headache sufferers had lower platelet levels of norepinephrine (NE) and epinephrine (E) in all phases of the syndrome. Tyrosine levels were increased significantly during the cluster headache attack. We suggest that these results provide biochemical evidence of sympathetic nervous system (SNS) hypofunction in cluster headache.
authors.affiliation: Department of Neurology, San Bortolo Hospital, Vicenza, Italy.
authors.forename: G
authors.initials: G
authors.lastname: D'Andrea
authors.forename: A R
authors.initials: AR
authors.lastname: Cananzi
authors.forename: M
authors.initials: M
authors.lastname: Morra
authors.forename: E
authors.initials: E
authors.lastname: Martignoni
authors.forename: S
authors.initials: S
authors.lastname: Fornasiero
authors.forename: F
authors.initials: F
authors.lastname: Zamberlan
authors.forename: S
authors.initials: S
authors.lastname: Grunfeld
authors.forename: K M
authors.initials: KM
authors.lastname: Welch
mesh_terms: D000328:Adult; D001792:Blood Platelets / Q000378:metabolism*; D003027:Cluster Headache / Q000097:blood*; D004837:Epinephrine / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000097:blood*; D014443:Tyrosine / Q000097:blood
chemical_list: D014443:Tyrosine; D009638:Norepinephrine; D004837:Epinephrine