Pregnancy outcome in women with rheumatoid arthritis before disease onset.
Pregnancy outcome before disease onset was evaluated for women with rheumatoid arthritis (RA) and control women as part of a prospective case-control study of newly diagnosed RA. An analysis of women who were ever gravid revealed no statistically significant difference in any adverse pregnancy outcome between RA cases (n = 144) and controls (n = 605) including spontaneous abortions and stillbirths. Thus, in contrast to reports both of an increase of adverse pregnancy outcomes and a decrease in women who subsequently develop RA, we found no evidence for any difference in pregnancy outcome in the RA group.
Nelson
J L
JL
Division of Clinical Research, Fred Hutchison Cancer Research Center, Seattle, WA 98104.
Voigt
L F
LF
Koepsell
T D
TD
Dugowson
C E
CE
Daling
J R
JR
D000022:Abortion, Spontaneous; D000293:Adolescent; D000328:Adult; D001172:Arthritis, Rheumatoid / Q000208:ethnology / Q000503:physiopathology*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D008913:Minority Groups; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D011446:Prospective Studies; D044469:Racial Groups