title: The structure of the F-actin filament and the actin molecule.
abstract: A consensus view on the three-dimensional structure of the F-actin filament and the relative strength of the intersubunit contacts in the filament has been established from an atomic filament model and recent three-dimensional reconstructions from electron micrographs of F-actin filaments. Functional implications of recent structural and biochemical data indicating a rather dynamic filament structure are discussed.
authors.affiliation: ME Müller-Institute for High-Resolution Electron Microscopy at the Biocenter, University of Basel, Basel, Switzerland.
authors.forename: A
authors.initials: A
authors.lastname: Bremer
authors.forename: U
authors.initials: U
authors.lastname: Aebi
mesh_terms: D008841:Actin Cytoskeleton / Q000737:chemistry* / Q000648:ultrastructure; D000199:Actins / Q000737:chemistry* / Q000648:ultrastructure; D000818:Animals; D008958:Models, Molecular; D011487:Protein Conformation; D013329:Structure-Activity Relationship
chemical_list: D000199:Actins