title: Unusual dentinal changes in dentinogenesis imperfecta associated with osteogenesis imperfecta. A case report.
abstract: A case is described of a boy with dentinogenesis imperfecta associated with osteogenesis imperfecta. The dentin of extracted deciduous teeth was found to show an abrupt transition to a normal tubular structure before a reversion to the more typical structure seen in dentinogenesis imperfecta. This change in the dentin appeared to have occurred in a chronologic manner. The possibilities that either a metabolic disturbance or a temporary reduced expression of the mutant gene had caused the abnormality and could account for the unusual histologic findings are discussed.
authors.affiliation: Institute of Medical Genetics, University of Wales College of Medicine, Cardiff.
authors.forename: M J
authors.initials: MJ
authors.lastname: Aldred
mesh_terms: D002648:Child; D002675:Child, Preschool; D003804:Dentin / Q000002:abnormalities / Q000473:pathology*; D003811:Dentinogenesis Imperfecta / Q000150:complications / Q000473:pathology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010013:Osteogenesis Imperfecta / Q000150:complications / Q000235:genetics / Q000473:pathology*; D014094:Tooth, Deciduous / Q000002:abnormalities