title: [Anal and perianal lesions in symptomatic HIV infections. Prospective study of a series of 190 patients].
abstract: The aim of this study was to determine the prevalence and type of symptomatic anal and perianal diseases in patients belonging to group IV of the Centers for Disease Control classification of infections with human immuno-deficiency virus. Among the 190 prospectively included patients, 31 (16.3 percent) (30 men, 29 homosexuals or bisexuals; 1 woman) had anal symptoms and were referred for proctological examination. Thirty-five "specific" diagnoses were reached in 25 (13.2 percent) patients: 21 ulcerations, 7 condyloma acuminata, 6 perianal sepsis and 1 non-Hodgkin malignant lymphoma. The causes of ulcerations were 16 herpes, one syphilitic chancre and one fissure-in-ano. Three ulcerations remained unexplained despite bacteriological, viral, and histological investigations. Eight patients underwent 10 surgical procedures without significantly delayed wound healing.
authors.affiliation: Service d'Hépato-Gastroentérologie, CHRU de Nancy-Brabois, Vandoeuvrelès-Nancy.
authors.forename: B J
authors.initials: BJ
authors.lastname: Denis
authors.forename: T
authors.initials: T
authors.lastname: May
authors.forename: M A
authors.initials: MA
authors.lastname: Bigard
authors.forename: P
authors.initials: P
authors.lastname: Canton
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000212:Acyclovir / Q000627:therapeutic use; D000328:Adult; D001004:Anus Diseases / Q000453:epidemiology* / Q000209:etiology; D001005:Anus Neoplasms / Q000453:epidemiology / Q000209:etiology; D003218:Condylomata Acuminata / Q000453:epidemiology / Q000209:etiology; D005260:Female; D006561:Herpes Simplex / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000150:complications / Q000188:drug therapy / Q000453:epidemiology; D015995:Prevalence; D011446:Prospective Studies; D014456:Ulcer / Q000453:epidemiology / Q000209:etiology
chemical_list: D000212:Acyclovir
vernacular_title: Lésions anales et péri-anales au cours des infections symptomatiques par le VIH. Etude prospective d'une série de 190 patients.