title: Thiamine status of elderly patients with cardiac failure.
abstract: This study compared the thiamine status of 37 elderly patients admitted with cardiac failure (CF) with that of 35 unselected elderly patients with other diagnoses (Non-CF), and with that of 41 apparently healthy elderly people. The thiamine pyrophosphate effect (TPPE) on erythrocyte transketolase activity was used to estimate thiamine status. The prevalence of thiamine deficiency (TPPE greater than 19%) on admission in the CF and Non-CF groups was 13% and 29%, respectively. The TPPE of the CF group was significantly lower than that of the Non-CF group, and was not significantly different from that of the elderly control group. The results indicate that thiamine deficiency is not common in an unselected group of elderly inpatients with cardiac failure, but a potential benefit of thiamine supplementation in such patients cannot be ruled out.
authors.affiliation: Department of Medicine for the Elderly, Leicester General Hospital.
authors.forename: T
authors.initials: T
authors.lastname: Kwok
authors.forename: J F
authors.initials: JF
authors.lastname: Falconer-Smith
authors.forename: J F
authors.initials: JF
authors.lastname: Potter
authors.forename: D R
authors.initials: DR
authors.lastname: Ives
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006333:Heart Failure / Q000097:blood / Q000209:etiology*; D006801:Humans; D007902:Length of Stay; D008297:Male; D009369:Neoplasms / Q000097:blood; D013831:Thiamine / Q000008:administration & dosage / Q000097:blood; D013832:Thiamine Deficiency / Q000097:blood / Q000150:complications*; D013835:Thiamine Pyrophosphate / Q000097:blood
chemical_list: D013835:Thiamine Pyrophosphate; D013831:Thiamine