Apophysomyces elegans as an agent of zygomycosis in a patient following trauma.
Apophysomyces elegans was isolated from the subcutaneous tissue, muscle and bone of a patient who had fallen from a height of 55 feet. Broad, sparsely septate hyphae were present in the tissue. Surgical debridement of wounds and amphotericin B treatment were not sufficient in controlling rapid tissue necrosis. Ultimately, amputation of the two affected limbs was necessary.
Huffnagle
K E
KE
Department of Pathology, University of Texas Southwestern Medical Center, Dallas 75235-9072.
Southern
P M
PM
Byrd
L T
LT
Gander
R M
RM
D000059:Accidents; D000328:Adult; D000671:Amputation, Surgical; D001132:Arm / Q000601:surgery; D005264:Femoral Fractures / Q000150:complications; D005360:Fibula / Q000293:injuries; D050723:Fractures, Bone / Q000150:complications; D006801:Humans; D006810:Humeral Fractures / Q000150:complications; D007866:Leg / Q000601:surgery; D008297:Male; D009090:Mucorales / Q000302:isolation & purification*; D009091:Mucormycosis / Q000150:complications / Q000382:microbiology* / Q000601:surgery; D009104:Multiple Trauma / Q000150:complications*; D013978:Tibial Fractures / Q000150:complications; D014949:Wounds, Nonpenetrating / Q000150:complications