title: The role of mammography to evaluate palpable breast tumours.
abstract: Mammography is the best screening tool at present available to detect early breast cancer in asymptomatic women. Its diagnostic ability to clarify the true nature of a palpable tumour in symptomatic breast disease remains controversial. To investigate this, case records of 115 women over 35 years, who presented clinically with a palpable and solid breast tumour over a 5 1/2-year period at Universitas Hospital, Bloemfontein, were retrospectively reviewed. All women were pre-operatively evaluated by clinical examination, mammography and fine-needle aspiration cytology and all patients subsequently underwent open surgical biopsy. Results of this triple diagnostic regimen were correlated to the final histopathological diagnosis. No differences in diagnostic accuracy could be found between mammography and either clinical or cytological diagnosis alone. Combining the clinical finding with that of either mammography or cytology significantly improved the diagnostic ability of both. Malignant disease diagnosed by cytology alone negated the additional diagnostic role of mammography in this context. However, to enable confirmation of a benign tumour, mammography proved to be an essential addition to clinical and cytological evaluation. Mammography correctly detected multicentricity in 7% of malignant tumours, proving it to be essential before breast-conserving surgery could be carried out for malignant tumours.
authors.affiliation: Department of Surgery, University of the Orange Free State, Bloemfontein.
authors.forename: R S
authors.initials: RS
authors.lastname: Du Toit
authors.forename: S P
authors.initials: SP
authors.lastname: Grobler
authors.forename: C
authors.initials: C
authors.lastname: Brink
authors.forename: P D
authors.initials: PD
authors.lastname: Divall
authors.forename: B D
authors.initials: BD
authors.lastname: Middlecote
authors.forename: C J
authors.initials: CJ
authors.lastname: Nel
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008327:Mammography; D012189:Retrospective Studies