title: Recurrent Lhermitte-Duclos disease: report of two cases and association with Cowden's disease.
abstract: Two cases of Lhermitte-Duclos disease (LDD), one associated with Cowden's disease, are reported. Both demonstrated recurrence long after initial surgical resection. There is a propensity for occurrence in the left cerebellar hemisphere. On MR there is hypointensity on T1-weighted images and moderately high signal on T2-weighted images, with parallel linear striations on the surface of the lesion felt to represent dysplastic cerebellar folia. LDD is felt to be a low-grade neoplasm and potential component of Cowden's phakomatosis.
authors.affiliation: Department of Radiology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC 27157-1022.
authors.forename: D W
authors.initials: DW
authors.lastname: Williams
authors.forename: A D
authors.initials: AD
authors.lastname: Elster
authors.forename: L E
authors.initials: LE
authors.lastname: Ginsberg
authors.forename: C
authors.initials: C
authors.lastname: Stanton
mesh_terms: D000328:Adult; D002526:Cerebellar Diseases / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006223:Hamartoma Syndrome, Multiple / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D013577:Syndrome; D014057:Tomography, X-Ray Computed