Marked cerebrospinal fluid pleocytosis in systemic lupus erythematosus related cerebral ischemia.
Pleocytosis of the cerebrospinal fluid (CSF) may accompany central nervous system lesions that occur as a result of systemic lupus erythematosus (SLE); however, the number of CSF white blood cells is usually less than 50/mm3 and the predominant cell is the lymphocyte. A young woman with SLE had 2 acute episodes of hemorrhagic cerebral ischemia, each of which was associated with a neutrophilic CSF pleocytosis (white blood count 480-2250/mm3). This type of meningeal reaction may have been related to the proximity of the cerebral lesions to the ventricles, a phenomenon previously described in non SLE related cerebral infarcts.
Abialmouna
J
J
Department of Medicine, Erie County Medical Center, Buffalo, NY.
Shoemaker
D W
DW
Pullicino
P M
PM
Baer
A N
AN
D000328:Adult; D002545:Brain Ischemia / Q000134:cerebrospinal fluid* / Q000175:diagnosis; D002536:Cerebral Arteries / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000134:cerebrospinal fluid / Q000175:diagnosis; D002555:Cerebrospinal Fluid / Q000166:cytology*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008279:Magnetic Resonance Imaging; D012008:Recurrence