Precautions when using opioid agonist-antagonist analgesics.
Agonist-antagonists are attractive because of their availability and absence of strict regulation. They do provide effective analgesia in many cases, and they are cost-effective. Incomplete analgesia can be noted in moderate to severe pain. Cardiopulmonary depression may be noted following agonist-antagonist administration. Interference with coadministered opiate agents may occur.
Raffe
M R
MR
Department of Small Animal Clinical Sciences, University of Minnesota, College of Veterinary Medicine, Saint Paul.
D000700:Analgesics / Q000009:adverse effects*; D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D006339:Heart Rate / Q000187:drug effects*; D009292:Narcotic Antagonists / Q000009:adverse effects*; D012119:Respiration / Q000187:drug effects*
D000700:Analgesics; D009292:Narcotic Antagonists