Methotrexate associated Peyronie's disease in the treatment of rheumatoid arthritis.
We describe two patients with rheumatoid arthritis treated with methotrexate (MTX) who developed Peyronie's disease during the course of their treatment. In one of the patients the penile fibrosis resolved on stopping the drug. The other patient's penile fibrosis partially resolved on stopping the drug. We suggest that Peyronie's disease can be a side-effect of MTX in the treatment of rheumatoid arthritis.
Phelan
M J
MJ
Department of Rheumatology, Whiston Hospital, Liverpool.
Riley
P L
PL
Lynch
M P
MP
D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000009:adverse effects / Q000627:therapeutic use*; D008875:Middle Aged; D010411:Penile Induration / Q000139:chemically induced*
D008727:Methotrexate