title: [Comparison of free amino acids in capillary and venous blood serum of children and adolescents with phenylketonuria and leucinosis].
abstract: Concentrations of free amino acids were determined quantitatively by ion exchange column chromatography in serum from capillary and venous blood of children and adolescents with phenylketonuria (n = 38) and leucinosis (n = 3). Serum was deproteinised by 5% sulphosalicylic acid (1:1, v/v). The results showed with exception of aspartic acid, glutamine and glutamic acid a very close correlation. The correlation coefficients ranged from 0.849 to 0.996. It is concluded that serum from capillary blood can be used for screening of amino acid metabolism.
authors.affiliation: Zentrum für Kinderheilkunde, Universität Bonn.
authors.forename: N
authors.initials: N
authors.lastname: Liappis
authors.forename: H
authors.initials: H
authors.lastname: Schlebusch
authors.forename: R
authors.initials: R
authors.lastname: Mallmann
mesh_terms: D000293:Adolescent; D000592:Amino Acid Metabolism, Inborn Errors / Q000097:blood* / Q000175:diagnosis; D000596:Amino Acids / Q000097:blood*; D002196:Capillaries; D002648:Child; D005260:Female; D006801:Humans; D007930:Leucine / Q000097:blood*; D008297:Male; D010661:Phenylketonurias / Q000097:blood* / Q000175:diagnosis; D014680:Veins
chemical_list: D000596:Amino Acids; D007930:Leucine
vernacular_title: Vergleich der freien Aminosäuren in Kapillar- und Venenblutserum von Kindern und Jugendlichen mit Phenylketonurie und Leucinose.