Valine is a precursor of propionyl-CoA.
For some time the metabolism of valine has been misrepresented by several biochemistry textbooks. This article demonstrates that propionyl-CoA occurs as an intermediate in the valine metabolic pathway before the formation of methylmalonyl CoA.
Kamoun
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University Rene Descartes, Department of Biochemical Genetics URA, CNRS 1335, Hospital Necker Enfants Malades, Paris, France.
D000214:Acyl Coenzyme A / Q000378:metabolism*; D000818:Animals; D006801:Humans; D008316:Malonyl Coenzyme A / Q000378:metabolism; D014633:Valine / Q000378:metabolism*
D000214:Acyl Coenzyme A; C015357:methylmalonyl-coenzyme A; C009061:propionyl-coenzyme A; D008316:Malonyl Coenzyme A; D014633:Valine