[Aminopyrine breath test in hepatic auto-transplantation in pigs].
The aminopyrine breath test (ABT) was performed during hepatic autotransplantation in the pig. The test is reproducible in this animal and only hepatic cytochromes perform the demethylation of aminopyrine. Ischemia, varying from 90 to 200 minutes, generated a major decrease in the elimination of the 14CO2 and a marked change in the elimination curve. In this specific model it was not possible to assess survival of the animal by the ABT.
Schopfer
C
C
Département de pharmacologie, Faculté de médecine, Université de Genève.
Belenger
J
J
Mentha
G
G
Pittet
J F
JF
Benakis
A
A
Rohner
A
A
D000632:Aminopyrine / Q000378:metabolism; D000818:Animals; D001944:Breath Tests; D016031:Liver Transplantation; D011184:Postoperative Period; D013552:Swine; D014182:Transplantation, Autologous
D000632:Aminopyrine
L'aminopyrine breath test (ABT) au cours de l'autotransplantation hépatique chez le porc.