title: Factors associated with the risk of developing sarcoid tumours in horses.
abstract: A retrospective case-control study was conducted to identify risk factors in horses associated with the development of the common skin tumours known as sarcoids. The study involved 503 sarcoid cases diagnosed (January 1980-December 1989) at New York State College of Veterinary Medicine and a similar number of controls (non-sarcoid cases). Data on age, breed and sex of cases and controls were obtained from computerised records. Multiple logistic regression analysis was used to identify risk factors. Separate data were obtained for the same 10-year period from the Veterinary Medical Data Program to determine the proportional morbidity rate at different veterinary colleges in North America. Appaloosa, Arabian and Quarter horses were at a higher risk of developing sarcoid tumours than were Thoroughbred horses. Standardbred horses had a lower risk of developing sarcoids. Geldings were at a higher risk of developing sarcoids in comparison with stallions. There was no significant difference in the risk of developing sarcoids between stallions and mares. The risk of developing sarcoid increased with age up to 15 years and then declined. The proportional morbidity rate of sarcoids among the veterinary colleges ranged between 0 and 14 per 1,000 cases, with an average of 6 per 1,000.
authors.affiliation: Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.
authors.forename: H O
authors.initials: HO
authors.lastname: Mohammed
authors.forename: W C
authors.initials: WC
authors.lastname: Rebhun
authors.forename: D F
authors.initials: DF
authors.lastname: Antczak
mesh_terms: D000367:Age Factors; D000818:Animals; D001947:Breeding; D016022:Case-Control Studies; D005260:Female; D006734:Horse Diseases / Q000453:epidemiology* / Q000209:etiology; D006736:Horses; D007889:Leiomyoma / Q000453:epidemiology / Q000209:etiology / Q000662:veterinary*; D008297:Male; D009017:Morbidity; D015999:Multivariate Analysis; D009518:New York / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D012878:Skin Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000662:veterinary*