In vivo pulsatile LHRH release into the anterior pituitary of the male rat: effects of castration.
The effects of castration on the concentration of luteinizing hormone releasing hormone (LHRH) in the anterior pituitary (PIT) was studied in freely-behaving male rats using a push-pull cannula for sampling. In over 70 perfusions of the PIT of rats sampled before and at multiple days after castration there was no consistent change detected in the overall amount, secretory pulse amplitude or frequency or the LHRH signal reaching the PIT.
Phelps
C P
CP
Department of Obstetrics and Gynecology, University of Florida, College of Medicine, Gainesville.
Kalra
S P
SP
Kalra
P S
PS
D000818:Animals; D007987:Gonadotropin-Releasing Hormone / Q000378:metabolism*; D008297:Male; D009919:Orchiectomy; D010477:Perfusion / Q000379:methods; D010902:Pituitary Gland / Q000378:metabolism / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values; D013997:Time Factors
D007987:Gonadotropin-Releasing Hormone