title: A case of primary biliary cirrhosis associated with Hashimoto's thyroiditis, scleroderma and Sjögren's syndrome.
abstract: A 53-year-old woman was admitted because of Raynaud's phenomenon, polyarthralgia and polymyalgia. Biopsy specimens of the liver and thyroid gland revealed characteristic findings of primary biliary cirrhosis (PBC) (stage I by Scheuer's classification) and chronic thyroiditis. Her clinical features were also complicated by scleroderma (type I by Barnett's classification) and Sjögren's syndrome (Sjs) with keratoconjunctivitis sicca. Thyroid hormone replacement therapy led to improvement in thyroid function, normalization of the biliary tract enzymes and alleviation of subjective symptoms.
authors.affiliation: First Department of Internal Medicine, Medical College of Oita, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Horita
authors.forename: N
authors.initials: N
authors.lastname: Takahashi
authors.forename: M
authors.initials: M
authors.lastname: Seike
authors.forename: S
authors.initials: S
authors.lastname: Nasu
authors.forename: R
authors.initials: R
authors.lastname: Takaki
mesh_terms: D001323:Autoantibodies / Q000097:blood; D001659:Biliary Tract / Q000201:enzymology; D005260:Female; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000150:complications* / Q000201:enzymology / Q000473:pathology; D008875:Middle Aged; D012594:Scleroderma, Localized / Q000150:complications*; D012859:Sjogren's Syndrome / Q000150:complications*; D013967:Thyroiditis, Autoimmune / Q000150:complications* / Q000276:immunology / Q000473:pathology
chemical_list: D001323:Autoantibodies