title: Current trends in the management of chronic myeloid leukaemia.
abstract: Conventional or alkylating treatment for chronic myeloid leukaemia has little impact on overall survival. Recent treatments, however, are encouraging. Alpha interferon may prolong the chronic phase in some patients, while allogeneic bone marrow transplantation is curative in over 50% of patients with HLA-compatible donors.
authors.affiliation: City Hospital, Nottingham.
authors.forename: S
authors.initials: S
authors.lastname: Rogers
authors.forename: N
authors.initials: N
authors.lastname: Russell
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D016026:Bone Marrow Transplantation / Q000276:immunology; D006086:Graft vs Host Disease / Q000517:prevention & control; D006680:HLA Antigens; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use; D015465:Leukemia, Myeloid, Accelerated Phase / Q000628:therapy; D015466:Leukemia, Myeloid, Chronic-Phase / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D014184:Transplantation, Homologous
chemical_list: D000970:Antineoplastic Agents; D006680:HLA Antigens; D016898:Interferon-alpha