title: Unilateral enucleation alters vasoactive intestinal polypeptide-like immunoreactivity in the suprachiasmatic nucleus of the rat.
abstract: Adult Sprague-Dawley rats were unilaterally enucleated under deep anesthesia and sacrificed 3-11 months post-operatively. The brains were removed and the suprachiasmatic nuclei were evaluated for vasoactive intestinal polypeptide (VIP)-like immunoreactivity. Our data show that expression of VIP is reduced in the nucleus that is deprived of retinal input.
authors.affiliation: Department of Anatomy, UMDNJ-New Jersey Medical School, Newark 07103.
authors.forename: L K
authors.initials: LK
authors.lastname: Laemle
mesh_terms: D000818:Animals; D015353:Eye Enucleation; D007124:Immunoenzyme Techniques; D051381:Rats; D011919:Rats, Inbred Strains; D012160:Retina / Q000502:physiology*; D013493:Suprachiasmatic Nucleus / Q000378:metabolism*; D014660:Vasoactive Intestinal Peptide / Q000378:metabolism*
chemical_list: D014660:Vasoactive Intestinal Peptide