title: Combined silicone and fluorosilicone oil tamponade (double filling) in the management of complicated retinal detachment.
abstract: We evaluated the use of simultaneous double filling with polydimethylsiloxane (PDMS) and fluorosilicone (FSiO) in the repair of complicated retinal detachment in 12 selected cases. Initial retinal reattachment was achieved in all cases. Proliferative vitreoretinopathy (PVR) recurred in 10 patients (83%), 6 of which showed partial retinal detachment. Inferior and superior postoperative residual free spaces were abolished by this procedure, but a new residual fluid space was created, lying horizontally between the bubbles and expanding in a triangular shape nasally to the optic disk and temporally to the macula. Overall, 9 of 10 eyes with postoperative PVR had proliferation involving these areas. These findings support the concept that 'compartmentalization' is of major importance in determining postoperative cell proliferation.
authors.affiliation: Institute of Biomedical Sciences, University of Milan, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Bottoni
authors.forename: P
authors.initials: P
authors.lastname: Arpa
authors.forename: P
authors.initials: P
authors.lastname: Vinciguerra
authors.forename: S
authors.initials: S
authors.lastname: Zenoni
authors.forename: V
authors.initials: V
authors.lastname: De Molfetta
mesh_terms: D000328:Adult; D004129:Dimethylpolysiloxanes / Q000008:administration & dosage*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology; D012008:Recurrence; D012163:Retinal Detachment / Q000601:surgery*; D012827:Silicone Oils / Q000008:administration & dosage*; D012828:Silicones / Q000008:administration & dosage*; D014821:Vitrectomy / Q000379:methods*
chemical_list: D004129:Dimethylpolysiloxanes; D012827:Silicone Oils; D012828:Silicones; C054077:fluorosilicone oil; C013830:baysilon