title: [Effectiveness of a liposomal form of rifampicin in the treatment of experimental tuberculosis in mice].
abstract: The therapeutic effectiveness of rifampicin as a free form and a component of multilamellar phosphatidylcholine cholesterol liposomes was studied on a model of generalized tuberculosis in BALB/c mice. Rifampicin as a liposomal form was found to have no advantages over its free form. Possible mechanisms of the phenomenon and prospects for using liposomes in the chemotherapy of tuberculosis are discussed.
authors.forename: Iu N
authors.initials: IuN
authors.lastname: Kurunov
authors.forename: V I
authors.initials: VI
authors.lastname: Kaledin
authors.forename: N A
authors.initials: NA
authors.lastname: Popova
authors.forename: A G
authors.initials: AG
authors.lastname: Panteleeva
mesh_terms: D000818:Animals; D004337:Drug Carriers; D008081:Liposomes; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D012293:Rifampin / Q000008:administration & dosage*; D014376:Tuberculosis / Q000188:drug therapy*
chemical_list: D004337:Drug Carriers; D008081:Liposomes; D012293:Rifampin
vernacular_title: Effektivnost' liposomal'noĭ formy rifampitsina pri lechenii éksperimental'nogo tuberkuleza mysheĭ.