[The specificity of the deposition of intratracheally administered plutonium in different skeletal bones with a change in iron homeostasis].
A study was made of the distribution of plutonium-239 injected intratracheally within different bones of the skeleton, the iron status in the blood being changed. The iron preparation caused a 2.5-3-fold decrease in the plutonium loading onto cancellous bone tissue that displayed, in ordinary conditions, a higher tropism to the radionuclide than a cortical highly mineralized bone did.
Rushonik
S I
SI
Ivanova
N P
NP
Shvydko
N S
NS
D000818:Animals; D001842:Bone and Bones / Q000187:drug effects / Q000378:metabolism*; D002951:Citrates / Q000008:administration & dosage; D019343:Citric Acid; D006706:Homeostasis / Q000187:drug effects / Q000528:radiation effects*; D007267:Injections; D007501:Iron / Q000097:blood*; D011005:Plutonium / Q000008:administration & dosage / Q000493:pharmacokinetics*; D051381:Rats; D013997:Time Factors; D014018:Tissue Distribution / Q000187:drug effects; D014132:Trachea
D002951:Citrates; D019343:Citric Acid; D011005:Plutonium; D007501:Iron
Spetsifika otlozheniia intratrakheal'no vvedennogo plutoniia v razlichnykh kostiakh skeleta pri izmenenii gomeostaza zheleza.