Molecular and classical cytogenetic analyses demonstrate an apomorphic reciprocal chromosomal translocation in Gorilla gorilla.
The existence of an apomorphic reciprocal chromosomal translocation in the gorilla lineage has been asserted or denied by various cytogeneticists. We employed a new molecular cytogenetic strategy (chromosomal in situ suppression hybridization) combined with high-resolution banding, replication sequence analysis, and fluorochrome staining to demonstrate that a reciprocal translocation between ancestral chromosomes homologous to human chromosome 5 and 17 has indeed occurred.
Stanyon
R
R
Istituto di Antropologia fisica, University of Genoa, Italy.
Wienberg
J
J
Romagno
D
D
Bigoni
F
F
Jauch
A
A
Cremer
T
T
D000818:Animals; D002871:Chromosome Banding; D002886:Chromosomes, Human, Pair 17; D002895:Chromosomes, Human, Pair 5; D015342:DNA Probes; D004261:DNA Replication; D015723:Gene Library; D006071:Gorilla gorilla / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D008251:Macaca / Q000235:genetics; D009693:Nucleic Acid Hybridization; D002679:Pan troglodytes / Q000235:genetics; D010957:Plasmids; D014178:Translocation, Genetic
D015342:DNA Probes