title: Development of a medical fiber-optic oxygen sensor based on optical absorption change.
abstract: A new fiber-optic oxygen sensor has been developed for use in medical applications. The sensor's viologen indicator becomes strongly absorbent after brief UV stimulation, and then returns to the transparent state. The rate of indicator return to transparency is proportional to the local oxygen concentration. Indicator absorbance is monitored with a red LED and receiving photodiode, and absorbance data are processed by a dedicated cpu. The solid-state sensor system has performance comparable to existing oxygen measurement techniques, and may be applicable for both in vitro and in vivo oxygen measurements.
authors.affiliation: Metricor Inc., Woodinville, WA 98072.
authors.forename: R A
authors.initials: RA
authors.lastname: Wolthuis
authors.forename: D
authors.initials: D
authors.lastname: McCrae
authors.forename: J C
authors.initials: JC
authors.lastname: Hartl
authors.forename: E
authors.initials: E
authors.lastname: Saaski
authors.forename: G L
authors.initials: GL
authors.lastname: Mitchell
authors.forename: K
authors.initials: K
authors.lastname: Garcin
authors.forename: R
authors.initials: R
authors.lastname: Willard
mesh_terms: D000042:Absorption; D004867:Equipment Design; D005336:Fiber Optic Technology / Q000295:instrumentation; D006801:Humans; D007202:Indicators and Reagents / Q000138:chemical synthesis / Q000737:chemistry; D008422:Materials Testing; D055100:Optical Fibers; D010084:Oxidation-Reduction; D010092:Oximetry / Q000295:instrumentation* / Q000379:methods; D010100:Oxygen / Q000097:blood*; D010777:Photochemistry; D012815:Signal Processing, Computer-Assisted; D014466:Ultraviolet Rays; D014755:Viologens / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D007202:Indicators and Reagents; D014755:Viologens; D010100:Oxygen