Trisomy 14 in two cases of granulosa cell tumor of the ovary.
Cytogenetic analysis of granulosa cell tumor of the ovary was performed in two patients. G-banding analysis of cells cultured 3-5 days showed that the karyotype of each tumor contained normal diploid cells as well as cells with identical aberration: trisomy 14. This is the first report of trisomy 14 in two cases of granulosa cell tumor of the ovary. Flow cytometric DNA content analysis was also performed.
Górski
G K
GK
Department of Pediatrics, Cooper Hospital/University Medical Center, Camden, NJ 08103.
McMorrow
L E
LE
Blumstein
L
L
Faasse
D
D
Donaldson
M H
MH
D000328:Adult; D002883:Chromosomes, Human, Pair 14; D005260:Female; D005434:Flow Cytometry; D006106:Granulosa Cell Tumor / Q000235:genetics*; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000235:genetics*; D014314:Trisomy; D014407:Tumor Cells, Cultured