[Rabbit liver secretes oxidated lipoproteins in experimental atherosclerosis].
It is shown in rabbits, that alimentary hypercholesterolemia proceeds with increasing lipid peroxidation in liver homogenate, blood serum and apo-B-containing lipoproteins. It is established in the model of liver perfusion in rabbits, that liver cells produce apo-B-containing level of lipid peroxidation. The lipid peroxidation increases in perfusate and in the fraction of lipoproteins (d less than 1,065 g/cm3) from this perfusate. Lipid peroxidation can interfere in the changing of physicochemical characteristics of lipoproteins at the stage of synthesis and secretion of lipoproteins by liver cells.
Panasenko
O M
OM
Sdvigova
A G
AG
Sergienko
V I
VI
Lopukhin
Iu M
IuM
D000818:Animals; D001161:Arteriosclerosis / Q000097:blood / Q000378:metabolism / Q000503:physiopathology*; D002784:Cholesterol / Q000097:blood; D004036:Diet, Atherogenic; D005260:Female; D066298:In Vitro Techniques; D015227:Lipid Peroxidation; D008074:Lipoproteins / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008297:Male; D011817:Rabbits
D008074:Lipoproteins; D002784:Cholesterol
Pechen' krolika pri éksperimental'nom ateroskleroze sekretiruet okislennye lipoproteiny.