title: Endometrial pattern and thickness associated with pregnancy outcome after assisted reproduction technologies.
abstract: The endometrial pattern and thickness was analysed prospectively on the day of administration of human chorionic gonadotrophin (HCG) in 200 in-vitro fertilization (IVF), gamete intra-Fallopian transfer (GIFT) and tubal embryo transfer (TET) cycles. Increasing maturity of the endometrial pattern was positively correlated with oestradiol levels (r = 0.20; P = 0.005), number of mature eggs (r = 0.13; P less than 0.05) and the number of top quality embryos (r = 0.40; P less than 0.001). The endometrial thickness was positively correlated with the number of follicles greater than or equal to 15 mm (r = 0.15; P less than 0.02) and the cycle day on which HCG was administered (r = 0.14; P less than 0.03). It was unaffected by the dose of human menopausal gonadotrophin and was negatively correlated with the use of clomiphene citrate (r = 0.40; P less than 0.001). Fecundity was increased for IVF when the endometrial thickness was greater than or equal to 9 mm (P less than 0.05) and for GIFT and TET when a Type C triple-line endometrial pattern was present (P less than 0.05). Biochemical pregnancies for the combined methods increased from 2.5% of all pregnancies when the endometrial thickness was 9-13 mm, to 27.8% when the thickness was less than 9 mm or greater than 13 mm (P less than 0.01). Biochemical pregnancies occurred in 67% of IVF pregnancies when the endometrial thickness was greater than or equal to 3 mm.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Fertility Institute, New Orleans, LA 70128.
authors.forename: R P
authors.initials: RP
authors.lastname: Dickey
authors.forename: T T
authors.initials: TT
authors.lastname: Olar
authors.forename: D N
authors.initials: DN
authors.lastname: Curole
authors.forename: S N
authors.initials: SN
authors.lastname: Taylor
authors.forename: P H
authors.initials: PH
authors.lastname: Rye
mesh_terms: D000328:Adult; D006063:Chorionic Gonadotropin / Q000097:blood; D004717:Endometrium / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D004958:Estradiol / Q000097:blood; D005260:Female; D005298:Fertility; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D010062:Ovulation Induction; D011247:Pregnancy; D011256:Pregnancy Outcome; D012099:Reproductive Techniques; D014463:Ultrasonography
chemical_list: D006063:Chorionic Gonadotropin; D004958:Estradiol; D007986:Luteinizing Hormone