[Similarity of drug therapy between schizophrenia and their first degree relatives].
61 pairs of probands and their first degree relatives who suffered from schizophrenia and once admitted to our hospital were analyzed. And according to the drugs used 61 pairs of patients were divided into two groups: concordance and disconcordance group. Estimation of these patients with General Assembly Scale (GAS) and the result suggests that there is significant difference of treatment efficiency between the probands and their first degree relatives of disconcordance group (P less than 0.05), but there is no significant difference in concordance or control groups respectively (P greater than 0.05). It seems that clinicians can choose drugs for first degree relatives according to the efficiency of drugs which probands used.
Wang
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Department of Genetics, Nanjing Neuro-Psychiatry Institute.
D000293:Adolescent; D000328:Adult; D000368:Aged; D005190:Family; D005260:Female; D006801:Humans; D008297:Male; D016555:Matched-Pair Analysis; D008875:Middle Aged; D012559:Schizophrenia / Q000188:drug therapy* / Q000235:genetics