title: [Hodgkin's disease. Our 9-year experience with the 1980 protocol].
abstract: The purpose of this work was to evaluate the therapeutic results attained with our 1980 protocol for Hodgkin's disease. The usefulness of staging laparotomy was also analysed. Along a 9-year period, 94 patients were diagnosed (stages IA and IIA: 26 cases, IB, IIB and IIIA: 24 cases, and IIIB and IV: 44 cases). The complete remission (CR) rate, as a whole, was 85%; there were 14 relapses, of whom a new CR was attained in 9 instances. The overall actuarial survival is 64% at 47 months. The appearance of 3 cases of acute non-lymphoblastic leukaemia is noteworthy. Laparotomy induced changes of the patient's staging in 49% of cases (rise in 43% and descent in 6%). In account of this, laparotomy seems an adequate procedure in staging, although the criteria for selecting the patients who will undergo this, procedure should be perhaps restrictive.
authors.affiliation: Servicio de Hematología y Hemoterapia, Hospital Ntra. Sra. de Aranzazu de San Sebastián.
authors.forename: J
authors.initials: J
authors.lastname: Marín
authors.forename: R
authors.initials: R
authors.lastname: Lasa
authors.forename: I
authors.initials: I
authors.lastname: Egurbide
authors.forename: M A
authors.initials: MA
authors.lastname: Etxebeste
authors.forename: E
authors.initials: E
authors.lastname: Bengoetxea
authors.forename: P
authors.initials: P
authors.lastname: Angulo
authors.forename: M
authors.initials: M
authors.lastname: Antigüedad
authors.forename: J R
authors.initials: JR
authors.lastname: Furundarena
authors.forename: F
authors.initials: F
authors.lastname: Peinado
authors.forename: E
authors.initials: E
authors.lastname: Navarro
mesh_terms: D000206:Actuarial Analysis; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D006689:Hodgkin Disease / Q000628:therapy*; D006801:Humans; D007813:Laparotomy; D008297:Male; D008466:Mechlorethamine / Q000008:administration & dosage; D009367:Neoplasm Staging; D011241:Prednisone / Q000008:administration & dosage; D011344:Procarbazine / Q000008:administration & dosage; D012074:Remission Induction; D013156:Splenectomy; D015996:Survival Rate; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D011344:Procarbazine; D008466:Mechlorethamine; D014750:Vincristine; D011241:Prednisone
vernacular_title: Enfermedad de Hodgkin. Nuestra experiencia de neuve años con el protocolo de 1980.