title: Crustacean neuropeptides: structures, functions and comparative aspects.
abstract: In this article, an attempt is made to review the presently known, completely identified crustacean neuropeptides with regard to structure, function and distribution. Probably the most important progress has been made in the elucidation of a novel family of large peptides from the X-organ-sinus gland system which includes crustacean hyperglycemic hormone (CHH), putative molt-inhibiting hormone (MIH) and vitellogenesis (= gonad)-inhibiting hormone (VIH). These peptides have so far only been found in crustaceans. Renewed interest in the neurohemal pericardial organs has led to the identification of a number of cardioactive/myotropic neuropeptides, some of them unique to crustaceans. Important contributions have been made by immunocytochemical mapping of peptidergic neurons in the nervous system, which has provided evidence for a multiple role of several neuropeptides as neurohormones on the one hand and as local transmitters or modulators on the other. This has been corroborated by physiological studies. The long-known chromatophore-regulating hormones, red pigment concentrating hormone (RPCH) and pigment-dispending hormone (PDH), have been placed in a broader perspective by the demonstration of an additional role as local neuromodulators. The scope of crustacean neuropeptide research has thus been broadened considerably during the last years.
authors.affiliation: Institut für Zoophysiologie, Universität Bonn, Federal Republic of Germany.
authors.forename: R
authors.initials: R
authors.lastname: Keller
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D003445:Crustacea / Q000737:chemistry*; D007447:Invertebrate Hormones / Q000737:chemistry / Q000502:physiology; D008969:Molecular Sequence Data; D009479:Neuropeptides / Q000737:chemistry / Q000502:physiology
chemical_list: D007447:Invertebrate Hormones; D009479:Neuropeptides