title: Management of post-traumatic acute renal failure with peritoneal dialysis.
abstract: To evaluate the efficacy of peritoneal dialysis (PD) in the management of post-traumatic renal failure, the authors reviewed the courses of five critically injured patients treated with PD over an 18-month period. Each patient had a double-cuffed PD catheter inserted through a subcutaneous tunnel with PD initiated within 48 hours. The dialysis prescription was individualized for each patient with frequent exchanges performed using either a manual manifold system or a continuous cycling machine. Three of the five patients survived and none of the survivors required dialytic therapy at discharge. Duration of PD ranged from 10 to 57 days. Three patients required intermittent hemodialysis (HD) due to progressive azotemia and hyperkalemia. Two patients developed bacterial peritonitis and three patients developed hyperglycemia with PD continuing without interruption in each patient. When compared to HD, PD offers the advantages of better hemodynamic tolerance, no anticoagulation, no vascular access, and a reduced personnel requirement if continuous cyclic PD is used.
authors.affiliation: Department of Surgery, Medical College of Georgia, Augusta 30912.
authors.forename: T R
authors.initials: TR
authors.lastname: Howdieshell
authors.forename: W E
authors.initials: WE
authors.lastname: Blalock
authors.forename: P A
authors.initials: PA
authors.lastname: Bowen
authors.forename: M L
authors.initials: ML
authors.lastname: Hawkins
authors.forename: C
authors.initials: C
authors.lastname: Hess
mesh_terms: D000046:Academic Medical Centers; D058186:Acute Kidney Injury / Q000097:blood / Q000209:etiology / Q000628:therapy*; D000328:Adult; D000368:Aged; D001806:Blood Urea Nitrogen; D003404:Creatinine / Q000097:blood; D005069:Evaluation Studies as Topic; D005845:Georgia / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009104:Multiple Trauma / Q000150:complications* / Q000209:etiology / Q000401:mortality; D010530:Peritoneal Dialysis / Q000295:instrumentation / Q000379:methods / Q000592:standards*; D015996:Survival Rate; D016896:Treatment Outcome
chemical_list: D003404:Creatinine