title: Hearing: the effects of chemicals.
abstract: Recent studies of human beings exposed to environmental chemicals, as well as experimental animal studies, have identified a number of chemical agents that are commercial products, chemical intermediaries, waste products, or contaminants that are potentially ototoxic. The classes of compounds discussed in this review include organic solvents, asphyxiant gases, and heavy metals that are present in the environment as industrial pollutants or byproducts. Both human and animal investigations are summarized in discussing the actions of these ototoxic compounds. The suggested gaps in our knowledge are highlighted to help direct future research.
authors.affiliation: Department of Surgery, School of Medicine, Southern Illinois University, Springfield 62794-9230.
authors.forename: L P
authors.initials: LP
authors.lastname: Rybak
mesh_terms: D000818:Animals; D002246:Carbon Disulfide / Q000009:adverse effects; D002248:Carbon Monoxide / Q000009:adverse effects; D004781:Environmental Exposure; D004782:Environmental Health; D034381:Hearing Loss / Q000139:chemically induced*; D006801:Humans; D007854:Lead / Q000009:adverse effects; D008630:Mercury Poisoning / Q000209:etiology; D012997:Solvents / Q000009:adverse effects; D014001:Tin / Q000009:adverse effects; D014050:Toluene / Q000009:adverse effects
chemical_list: D012997:Solvents; D007854:Lead; D014050:Toluene; D014001:Tin; D002248:Carbon Monoxide; D002246:Carbon Disulfide