Detection of a frequent polymorphism in exon 10 of the low-density lipoprotein receptor gene.
DNA sequencing of enzymatically-amplified exons of the low-density lipoprotein receptor gene from several individuals revealed a polymorphism in exon 10 of the gene. The codon for arginine 450 was converted from AGG to AGA in some alleles.
Warnich
L
L
Department of Human Genetics, Faculty of Medicine, University of Stellenbosch, Tygerberg, South Africa.
Kotze
M J
MJ
Langenhoven
E
E
Retief
A E
AE
D000483:Alleles; D001120:Arginine / Q000235:genetics; D001483:Base Sequence; D005091:Exons / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics; D009838:Oligodeoxyribonucleotides / Q000235:genetics; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic / Q000235:genetics*; D011973:Receptors, LDL / Q000235:genetics*
D009838:Oligodeoxyribonucleotides; D011973:Receptors, LDL; D001120:Arginine