Lentigo maligna. Cytogenetic, ultrastructural, and phenotypic characterization of a primary cell culture.
Lentigo maligna is an early cutaneous neoplastic lesion. This article presents the cytogenetic, ultrastructural, and phenotypic characterization of a primary cell culture obtained from a patient affected with lentigo maligna. Two cellular clones were identified, both characterized by chromosomal markers involving chromosome 10 with a breakpoint at 10q26.
Grammatico
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P
Dipartimento di Medicina Sperimentale, Università degli Studi di Roma La Sapienza, Italy.
Modesti
A
A
Steindl
K
K
Scarpa
S
S
Heouaine
A
A
Picardo
M
M
Del Porto
G
G
D002872:Chromosome Deletion; D002879:Chromosomes, Human, Pair 10; D005455:Fluorescent Antibody Technique; D006801:Humans; D007911:Lentigo / Q000235:genetics* / Q000473:pathology; D008297:Male; D008544:Melanocytes / Q000473:pathology; D008545:Melanoma / Q000235:genetics* / Q000473:pathology; D008854:Microscopy, Electron; D008875:Middle Aged; D012878:Skin Neoplasms / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic / Q000235:genetics*; D014407:Tumor Cells, Cultured; D014746:Vimentin / Q000032:analysis
D014746:Vimentin