[Cardiovascular effects of kainic acid injected into habenular nucleus].
The present study was to determine if the cardiovascular effect being produced by exciting cells in the habenular nucleus (Hab). Experiments were performed on urethane-anesthetized rats. Microinjection of kainic acid into Hab demonstrated dose-dependent increases in arterial blood pressure and heart rate, accompanied by other sympathetic reactions, such as mydriasis and pilo-erection. But microinjection of lidocaine into Hab did not elicit similar effects mentioned above.
Yang
S N
SN
Department of Physiology, Norman Bethune University of Medical Sciences, Changchun, China.
Tang
Y H
YH
Wang
S
S
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D007608:Kainic Acid / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D008845:Microinjections; D051381:Rats; D011919:Rats, Inbred Strains; D013787:Thalamic Nuclei
D007608:Kainic Acid