title: Results of coronary artery surgery in young adults.
abstract: To study the results of bypass surgery in young adults, 221 patients undergoing myocardial revascularisation aged 40 or less (1979-1989) were reviewed. The study included 200 men and 21 women. Mean age was 36.2 years. Risk factors were essentially cigarette smoking (69.6%) and hyperlipidaemia (52%). One-hundred and eighteen patients (53.4%) had a history of previous myocardial infarction (MI) and 16 were operated on after an episode of preinfarction angina. One-hundred and twenty-nine patients had three-vessel disease, 59 had double-vessel disease and 33 single-vessel disease. Twenty-three had left main stem coronary artery lesions. Four-hundred and forty-six saphenous vein grafts and 79 internal mammary artery grafts were performed, an average of 2.3 grafts per patient. Operative mortality was 2.7% (6 patients). Deaths were caused in 4 cases by MI. Twelve patients (5.5%) had a non fatal perioperative MI. One-hundred and ninety-nine patients were followed up for a mean of 7.4 years (4838 patients-years). Seventeen late deaths occurred. Six were from cardiac causes. Overall survival was 84% at 9 years. Five patients underwent cardiac reoperation at a mean interval of 6.4 years after the primary procedure. Eighty-five% of patients were free of angina and 11.5% were in an improved condition. In conclusion, coronary revascularisation can be performed at a reduced risk in younger patients. Long-term prognosis seems similar to that of the overall group of patients undergoing bypass surgery.
authors.affiliation: Service de Chirurgie Cardiovasculaire, Hôpital de la Pitié, Paris, France.
authors.forename: P
authors.initials: P
authors.lastname: Nataf
authors.forename: S
authors.initials: S
authors.lastname: Parikh
authors.forename: G
authors.initials: G
authors.lastname: Rabago
authors.forename: M
authors.initials: M
authors.lastname: Fontanel
authors.forename: V
authors.initials: V
authors.lastname: Bors
authors.forename: A
authors.initials: A
authors.lastname: Pavie
authors.forename: C
authors.initials: C
authors.lastname: Cabrol
authors.forename: I
authors.initials: I
authors.lastname: Gandjbakhch
mesh_terms: D000328:Adult; D001026:Coronary Artery Bypass / Q000401:mortality / Q000706:statistics & numerical data; D003324:Coronary Artery Disease / Q000453:epidemiology / Q000401:mortality / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D010297:Paris / Q000453:epidemiology; D011183:Postoperative Complications / Q000453:epidemiology; D012086:Reoperation / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors