Chloral hydrate overdose: trichloroethanol detection by gas chromatography/mass spectrometry.
A case is presented where an individual ingested a fatal dose of chloral hydrate. Trichloroethanol (TCE), the metabolite of chloral hydrate, was initially identified by the Fujiwara reaction and quantified by gas chromatography/mass spectrometry in blood )127 mg/l), urine (128 mg/l) and stomach contents (25 mg total).
Heller
P F
PF
Department of Biomedicinal Chemistry, University of Maryland, Baltimore 21201.
Goldberger
B A
BA
Caplan
Y H
YH
D000328:Adult; D002697:Chloral Hydrate / Q000493:pharmacokinetics / Q000506:poisoning*; D062787:Drug Overdose / Q000175:diagnosis; D005023:Ethylene Chlorohydrin / Q000031:analogs & derivatives* / Q000032:analysis; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry; D005766:Gastrointestinal Contents / Q000737:chemistry*; D006207:Half-Life; D006801:Humans; D013405:Suicide
D002697:Chloral Hydrate; D005023:Ethylene Chlorohydrin; C005849:2,2,2-trichloroethanol