title: Transcription in Drosophila melanogaster salivary gland cells is altered following exposure to low-frequency electromagnetic fields: analysis of chromosome 3R.
abstract: The use of the transcription autoradiographic method permits identification of nascent RNA chains directly on identifiable regions of Drosophila salivary gland chromosomes. Changes in transcriptional activity at 13 defined regions of the right arm of chromosome 3 (3R) were observed following 20-min exposures of salivary glands to five different extremely low frequency (ELF) electromagnetic (EM) fields. Changes in translational patterns were also induced by the ELF EM fields in exposed cells. Differences included an increase in over-all polypeptide synthesis as well as in the number of polypeptides resolved in cells exposed to EM fields.
authors.affiliation: Columbia University Health Sciences, Hunter College, City University of New York.
authors.forename: R
authors.initials: R
authors.lastname: Goodman
authors.forename: D
authors.initials: D
authors.lastname: Weisbrot
authors.forename: A
authors.initials: A
authors.lastname: Uluc
authors.forename: A
authors.initials: A
authors.lastname: Henderson
mesh_terms: D000818:Animals; D001345:Autoradiography; D002875:Chromosomes / Q000648:ultrastructure*; D004331:Drosophila melanogaster; D004574:Electromagnetic Fields; D012469:Salivary Glands / Q000166:cytology*; D014158:Transcription, Genetic