title: Prolonged proestrus in a bitch with X chromosomal monosomy (77,XO).
abstract: A stunted Miniature American Eskimo bitch that had signs of proestrus, which persisted for almost 8 months, had a 77,XO karyotype. Despite signs of proestrus, the ovaries were small and fibrous, and there was no evidence of ovarian follicle development or corpora lutea. Except for its juvenile appearance, the rest of the reproductive tract was grossly normal. Clinical signs in this bitch were similar to those in human beings with Turner's syndrome.
authors.affiliation: Department of Medicine, Tufts School of Veterinary Medicine, North Grafton, MA 01536.
authors.forename: R M
authors.initials: RM
authors.lastname: Löfstedt
authors.forename: L C
authors.initials: LC
authors.lastname: Buoen
authors.forename: A F
authors.initials: AF
authors.lastname: Weber
authors.forename: S D
authors.initials: SD
authors.lastname: Johnston
authors.forename: A
authors.initials: A
authors.lastname: Huntington
authors.forename: P W
authors.initials: PW
authors.lastname: Concannon
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D005836:Genitalia, Female / Q000473:pathology; D007621:Karyotyping / Q000662:veterinary; D007986:Luteinizing Hormone / Q000097:blood; D009006:Monosomy; D011359:Proestrus / Q000235:genetics*; D014960:X Chromosome
chemical_list: D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone