Chronic microsporidian infection of the nasal mucosae, sinuses and conjunctivae in HIV disease.
A case of chronic infection of the nasal mucosae, sinuses and conjunctivae with a microsporidian parasite in association with HIV infection and immune deficiency is reported. This microsporidian resembles both Encephalitozoon cuniculi and the newly described Encephalitozoon hellem by electron microscopy. This occurred in an adult male resident in the UK with no history of foreign travel. Although there are previous descriptions of conjunctival infections from the USA, this is the first description of infection of the nasal epithelium. Further studies are underway to classify this protozoan.
Lacey
C J
CJ
Department of Genitourinary Medicine, General Infirmary, Leeds, UK.
Clarke
A M
AM
Fraser
P
P
Metcalfe
T
T
Bonsor
G
G
Curry
A
A
D000328:Adult; D000818:Animals; D001727:Bisexuality; D002908:Chronic Disease; D003228:Conjunctiva / Q000469:parasitology*; D015658:HIV Infections / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008854:Microscopy, Electron; D016881:Microsporidiosis / Q000150:complications* / Q000000981:diagnostic imaging; D009297:Nasal Mucosa / Q000469:parasitology*; D009894:Opportunistic Infections / Q000150:complications* / Q000000981:diagnostic imaging; D010256:Paranasal Sinuses / Q000000981:diagnostic imaging / Q000469:parasitology*; D011859:Radiography