title: Intraindividual variability of anorectal manometry parameters.
abstract: The present study investigates the intraindividual day-to-day variability of anorectal manometry parameters. Manometric studies were performed in twelve healthy volunteers on three different days. A low compliance capillary perfusion system was used. The values measured on day 1 and day 2, as well as those on day 2 and day 3, showed no significant (p greater than 0.05) differences for any parameter in Wilcoxon's test. Mean percentage of differences as a measure for intraindividual day-to-day variation was relatively low for anal resting (mean: 13.5%) and maximal squeeze (17.5%) pressure. However, it was high for the threshold volumes for minimal perception (71.8%) and urgency to defecate (38.5%) during rectal balloon distention as well as for the minimal volume required to abolish recovery of the rectoanal inhibitory reflex (41.2%). We conclude that anal resting pressure and maximal squeeze pressure both are the most stable anorectal manometry parameters in man, at least over a period of a few days.
authors.affiliation: I. Department of Medicine, University of Mainz, Germany, Bundesrepublik, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Göke
authors.forename: K
authors.initials: K
authors.lastname: Donner
authors.forename: K
authors.initials: K
authors.lastname: Ewe
authors.forename: K H
authors.initials: KH
authors.lastname: Meyer zum Büschenfelde
mesh_terms: D000328:Adult; D001003:Anal Canal / Q000503:physiopathology*; D005242:Fecal Incontinence / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry / Q000295:instrumentation*; D008838:Microcomputers; D012007:Rectum / Q000503:physiopathology*; D012016:Reference Values; D012684:Sensory Thresholds / Q000502:physiology; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*