title: Auditory function in patients infected with the human immunodeficiency virus.
abstract: A prospective study of auditory function in 18 HIV positive male patients at different CDC (Centres for Disease Control) stages was undertaken. One-third had abnormalities on either auditory evoked response testing or pure tone audiometry. No correlation was found between interwave latencies I-V, I-III, III-V and stage of disease determined either clinically or by T-cell subset. There was a weak correlation between pure tone averages at 1,2,4 kHz and 2,4,8 kHz and T-cell subset ratio in CDC Group IV disease (Rs = 0.56 and 0.57 respectively; P less than 0.05). Abnormalities of BSER were similar to those previously reported in HIV infection, and suggest isolated changes within the brain-stem.
authors.affiliation: Department of ENT Surgery, St Mary's Hospital, London, UK.
authors.forename: M A
authors.initials: MA
authors.lastname: Birchall
authors.forename: R G
authors.initials: RG
authors.lastname: Wight
authors.forename: P D
authors.initials: PD
authors.lastname: French
authors.forename: Z
authors.initials: Z
authors.lastname: Cockbain
authors.forename: S J
authors.initials: SJ
authors.lastname: Smith
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000503:physiopathology; D000328:Adult; D001301:Audiometry, Pure-Tone; D001309:Auditory Threshold / Q000502:physiology; D003638:Deafness / Q000503:physiopathology; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D015658:HIV Infections / Q000503:physiopathology*; D006679:HIV Seropositivity / Q000503:physiopathology*; D006309:Hearing / Q000502:physiology*; D006801:Humans; D008297:Male; D011446:Prospective Studies; D011930:Reaction Time / Q000502:physiology; D014012:Tinnitus / Q000503:physiopathology