title: Pseudosarcomatous myofibroblastic proliferations of the spermatic cord ("proliferative funiculitis"). Histologic and immunohistochemical analysis of a distinctive entity.
abstract: Pseudosarcomatous myofibroblastic proliferations have been recognised at a variety of sites. We describe five lesions of the spermatic cord, four of which were incidental findings at inguinal herniorrhaphy. The patients' age range was 52-76 years. In all cases, sarcoma was suspected histologically, but each lesion showed morphologic features in keeping with fasciitis-like lesions described at other sites. Two cases showed actin positivity, supporting this interpretation. All were marginally or incompletely excised. One recurred locally. We believe that ischemia or torsion is of pathogenetic importance at this site. We propose that the term "proliferative funiculitis" be used to describe this type of reactive process when it presents in the spermatic cord.
authors.affiliation: Department of Histopathology, St Thomas's Hospital, London, England.
authors.forename: K
authors.initials: K
authors.lastname: Hollowood
authors.forename: C D
authors.initials: CD
authors.lastname: Fletcher
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D005350:Fibroma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D005832:Genital Diseases, Male / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D005834:Genital Neoplasms, Male / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D007249:Inflammation / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013085:Spermatic Cord / Q000473:pathology*; D009626:Terminology as Topic