Understanding circulatory shock. Is it hypovolemic, cardiogenic, or vasogenic?
Circulatory shock comprises a group of complex circulatory syndromes that result from a variety of conditions. It alters the function of most organ systems and has very high mortality. Identification of the type of shock (hypovolemic, cardiogenic, vasogenic, or a combination) and optimal treatment are aided by hemodynamic monitoring, including determination of preload, cardiac output, and systemic vascular resistance. Experimental studies and isolation of bioactive substances have improved understanding of the mechanisms involved in shock. Restoration of intravascular volume, cardiac contractility, and vascular tone and control of the underlying septic process when applicable are the basis of current therapy. Close monitoring and support of the affected organ systems in an intensive care environment facilitate recovery. Encouraging results with new treatments indicate improved chances for a satisfactory outcome in patients with circulatory shock.
Teba
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L
Department of Medicine, West Virginia University School of Medicine, Morgantown 26506.
Banks
D E
DE
Balaan
M R
MR
D006801:Humans; D012769:Shock / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D012770:Shock, Cardiogenic / Q000175:diagnosis / Q000628:therapy