[Burkitt's lymphoma with granulocytosis and a high level of C-reactive protein].
A case of Burkitt's lymphoma with granulocytosis including immature cells and a high level of C-reactive protein (CRP) is reported. The activity of interleukin-1 alpha (IL-1 alpha) was detected in the sera, although its activity was not detected in the supernate of the cultured lymphoblasts. The lymphoblasts stimulated production of IL-1 alpha from human umbilical endothelial cells. Therefore, the lymphoblasts infiltrating bone marrow may have stimulated production of IL-1 alpha from bone marrow stroma cells, and IL-1 alpha may have induced granulocytosis and a high level of CRP.
Muroi
K
K
Department of Medicine, Jichi Medical School.
Izumi
T
T
Yoshida
M
M
Suda
T
T
Miwa
A
A
Sakamoto
S
S
Miura
Y
Y
D000368:Aged; D002051:Burkitt Lymphoma / Q000097:blood* / Q000150:complications; D002097:C-Reactive Protein / Q000032:analysis*; D006098:Granulocytes; D006801:Humans; D007964:Leukocytosis / Q000150:complications*; D008297:Male
D002097:C-Reactive Protein