title: Hemangiopericytoma of the head and neck region. A clinical and morphological study of three cases.
abstract: Whereas the morphological picture allows classification of malignant hemangiopericytomas with great accuracy, classification of hemangiopericytomas exhibiting a histologically and cytologically benign picture can be difficult. Three hemangiopericytomas of the head could be studied in detail both clinically and morphologically. Inspite of light, scanning and transmission electron microscopic, immunohistochemical and electron microscopic studies no reliable histological criteria indicative of the biological pattern of so-called "benign" hemangiopericytoma could be found. Thus, it appears appropriate to consider all hemangiopericytomas as potentially malignant.
authors.affiliation: Department of Pathology, Ruhr University Bochum, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Philippou
authors.forename: N C
authors.initials: NC
authors.lastname: Gellrich
mesh_terms: D008841:Actin Cytoskeleton / Q000737:chemistry / Q000648:ultrastructure; D000328:Adult; D001485:Basement Membrane / Q000737:chemistry / Q000648:ultrastructure; D005260:Female; D006393:Hemangiopericytoma / Q000737:chemistry / Q000473:pathology*; D006470:Hemorrhage / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D008938:Mitosis; D009336:Necrosis; D012888:Skull Neoplasms / Q000737:chemistry / Q000473:pathology*; D014746:Vimentin / Q000032:analysis; D000514:alpha 1-Antichymotrypsin / Q000032:analysis; D000515:alpha 1-Antitrypsin / Q000032:analysis
chemical_list: D014746:Vimentin; D000514:alpha 1-Antichymotrypsin; D000515:alpha 1-Antitrypsin