title: Dental amalgam and mercury.
abstract: The mercury concentrations in blood (HgB) and urine (HgU) samples, and in exhaled air (HgAir) were measured in 147 individuals from an urban Norwegian population, using cold vapour atomic absorption spectrometry. The study aimed to estimate the mercury exposure from the dental restorations, by correlating the data to the presence of amalgam restorations. Mean values were HgB = 24.8 nmol/l, HgU = 17.5 nmol/l and HgAir = 0.8 micrograms/m3. HgU correlated with HgAir, and both HgU and HgAir with the number of amalgam restorations, amalgam restored surfaces and amalgam restored occlusal surfaces. HgB showed poor correlation to HgU and HgAir and the presence of amalgam restorations. A differentiation of the mercury absorption due to exposure from dental amalgams and from the dietary intake, necessitates measurements of both organic and inorganic mercury in the plasma, and in the erythrocytes. The results suggest that individuals with many amalgam restorations, i.e., more than 36 restored surfaces, absorb 10-12 micrograms Hg/day.
authors.affiliation: Department of Anatomy, Dental Faculty, University of Oslo, Norway.
authors.forename: A
authors.initials: A
authors.lastname: Jokstad
authors.forename: Y
authors.initials: Y
authors.lastname: Thomassen
authors.forename: E
authors.initials: E
authors.lastname: Bye
authors.forename: J
authors.initials: J
authors.lastname: Clench-Aas
authors.forename: J
authors.initials: J
authors.lastname: Aaseth
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000388:Air / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D003723:Dental Amalgam / Q000493:pharmacokinetics*; D005260:Female; D006801:Humans; D008297:Male; D008628:Mercury / Q000097:blood / Q000378:metabolism* / Q000652:urine; D008875:Middle Aged
chemical_list: D003723:Dental Amalgam; D008628:Mercury