[Comparison of free amino acids in capillary and venous blood serum of children and adolescents with phenylketonuria and leucinosis].
Concentrations of free amino acids were determined quantitatively by ion exchange column chromatography in serum from capillary and venous blood of children and adolescents with phenylketonuria (n = 38) and leucinosis (n = 3). Serum was deproteinised by 5% sulphosalicylic acid (1:1, v/v). The results showed with exception of aspartic acid, glutamine and glutamic acid a very close correlation. The correlation coefficients ranged from 0.849 to 0.996. It is concluded that serum from capillary blood can be used for screening of amino acid metabolism.
Liappis
N
N
Zentrum für Kinderheilkunde, Universität Bonn.
Schlebusch
H
H
Mallmann
R
R
D000293:Adolescent; D000592:Amino Acid Metabolism, Inborn Errors / Q000097:blood* / Q000175:diagnosis; D000596:Amino Acids / Q000097:blood*; D002196:Capillaries; D002648:Child; D005260:Female; D006801:Humans; D007930:Leucine / Q000097:blood*; D008297:Male; D010661:Phenylketonurias / Q000097:blood* / Q000175:diagnosis; D014680:Veins
D000596:Amino Acids; D007930:Leucine
Vergleich der freien Aminosäuren in Kapillar- und Venenblutserum von Kindern und Jugendlichen mit Phenylketonurie und Leucinose.