[Hepatic metastasis of non-colorectal cancers. Results of surgical treatment].
To evaluate long-term results after curative hepatic resection for metastases from non-colorectal cancers, eleven studies published between 1978 and 1991 were reviewed. Data from 255 patients were available. Among these 255 patients, hepatic metastases were originating from 35 different primitive tumors. Breast cancers were the most frequent primitive tumors (n = 34, 13%). Following hepatic resection, Wilm's tumors and endocrine tumors gave the best results (five-year survival rate superior to 50%). Despite hepatic resection, melanomas and pancreatic cancers remained of poor prognosis. In breast cancers, when hepatic surgery was associated with adjuvant chemotherapy, the five-year cumulative survival was 16%. For leiomyosarcomas, gastric adenocarcinomas and gallbladder cancers few cases of prolonged survival have been recorded. These results suggest that in a selected group, surgery could be contemplate with chance of cure. Multicentric studies and/or a national register, would allow to improve the selection of patients and to optimize the surgical approach.
Mariette
D
D
Service de chirurgie digestive, hôpital Henri-Mondor, Créteil.
Fagniez
P L
PL
D001943:Breast Neoplasms / Q000473:pathology*; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery; D011379:Prognosis
Les métastases hépatiques des cancers non colo-rectaux. Résultats du traitement chirurgical.