Spitz naevus of the toe.
A 68-year-old Japanese woman presented with a brownish macule, containing two papules, on her left fourth toe. Histological examination revealed an intradermal epithelioid cell tumour with irregularly shaped, bizarre giant cells. In the upper portion of the tumour, the epithelioid cells contained abundant melanin. A low amount of 5-S-cysteinyldopa and a diploid DNA distribution histographic pattern were helpful in differentiating the lesion from malignant melanoma. This location of a Spitz naevus is exceptional.
Nogita
T
T
Department of Dermatology, Tokyo Women's Medical College, Japan.
Nagayama
M
M
Kawashima
M
M
Hidano
A
A
Kasori
J
J
Morishima
T
T
D000368:Aged; D004273:DNA, Neoplasm / Q000032:analysis; D004171:Diploidy; D005260:Female; D006801:Humans; D007564:Japan; D009508:Nevus, Pigmented / Q000235:genetics / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*; D014034:Toes
D004273:DNA, Neoplasm