Evidence that Rieger syndrome maps to 4q25 or 4q27.
We report a baby with the features of Rieger syndrome and a de novo interstitial deletion of 4q which includes band 4q26 and an adjoining GTL light band, either q25 or q27. Rieger syndrome is provisionally mapped to 4q23----q27 but band 4q26 has been excluded as a possible site, suggesting that Rieger syndrome must map to a band, either 4q25 or 4q27, adjoining 4q26.
Vaux
C
C
Victorian Clinical Genetics Services, Murdoch Institute, Royal Children's Hospital, Australia.
Sheffield
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L
Keith
C G
CG
Voullaire
L
L
D000848:Anodontia / Q000235:genetics*; D000867:Anterior Chamber / Q000002:abnormalities*; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D002894:Chromosomes, Human, Pair 4; D005260:Female; D006801:Humans; D007223:Infant; D007621:Karyotyping