title: Oxyntic and antral gastritis in the People's Republic of China: diagnosis and relationship to Helicobacter pylori.
abstract: This study investigates the relationship between gastritis and Helicobacter pylori infection in the Chinese population. Particular focus was placed upon the grading of gastritis, using the recently developed "Sydney system." Five diagnostic procedures were used to establish H. pylori status, all of which were found to be highly sensitive and specific. Histological chronic gastritis was reported in 93/108 (86.1%) of the patients examined, H. pylori infection being present in 73/93 (78.5%), and in no patient with histologically normal mucosae. There was a relatively high incidence of idiopathic antral gastritis within the gastritic population, 20/93 (21.5%). In the H. pylori-positive group, 10/73 (13.7%) had pangastritis, 57/73 (78.1%) had pangastritis-antrum-predominant, and 6/73 (8.2%) had antral-only gastritis. The level of activity was significantly higher in the antrum; however, the distribution of bacteria between the antrum and body was not significantly different. There is a need for additional studies examining the specific topographical relationship between H. pylori, the histology, and gastroduodenal disease.
authors.affiliation: Affiliated First Hospital, Sun Yat-Sen University of Medical Science, Guangzhou, People's Republic of China.
authors.forename: P J
authors.initials: PJ
authors.lastname: Hu
authors.forename: Y Y
authors.initials: YY
authors.lastname: Li
authors.forename: H M
authors.initials: HM
authors.lastname: Mitchell
authors.forename: M H
authors.initials: MH
authors.lastname: Zhou
authors.forename: M H
authors.initials: MH
authors.lastname: Chen
authors.forename: G G
authors.initials: GG
authors.lastname: Du
authors.forename: B J
authors.initials: BJ
authors.lastname: Huang
authors.forename: A
authors.initials: A
authors.lastname: Lee
authors.forename: S L
authors.initials: SL
authors.lastname: Hazell
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002681:China; D002908:Chronic Disease; D005260:Female; D005756:Gastritis / Q000175:diagnosis* / Q000382:microbiology; D005773:Gastroscopy; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010295:Parietal Cells, Gastric / Q000382:microbiology / Q000473:pathology; D011237:Predictive Value of Tests; D011706:Pyloric Antrum / Q000382:microbiology / Q000473:pathology; D012680:Sensitivity and Specificity; D012698:Serologic Tests