title: Septic bone, joint and muscle lesions associated with human immunodeficiency virus infection.
abstract: Ten episodes of musculoskeletal sepsis have been seen in nine patients with HIV infection. Seven patients had AIDS, circulating CD4-positive lymphocyte counts being less than 0.1 x 10(9)/l in six. Septic arthritis recurred in seven patients, osteomyelitis in three and pyomyositis and bursitis each occurred in one patient. Staphylococcus aureus was isolated from four patients, atypical micro-organisms being found in three. Presentation of musculoskeletal infection in this patient group may be atypical but rapid diagnosis is important as early antimicrobial therapy is often successful.
authors.affiliation: Department of Rheumatology, Westminster Hospital, London.
authors.forename: R A
authors.initials: RA
authors.lastname: Hughes
authors.forename: I F
authors.initials: IF
authors.lastname: Rowe
authors.forename: D
authors.initials: D
authors.lastname: Shanson
authors.forename: A C
authors.initials: AC
authors.lastname: Keat
mesh_terms: D000328:Adult; D001170:Arthritis, Infectious / Q000150:complications*; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006679:HIV Seropositivity / Q000150:complications; D006467:Hemophilia A / Q000150:complications; D006801:Humans; D007596:Joints / Q000382:microbiology / Q000473:pathology; D008297:Male; D009141:Musculoskeletal System / Q000382:microbiology / Q000473:pathology; D010019:Osteomyelitis / Q000150:complications