Carbohydrate metabolism after three months of using a gestodene-containing monophasic oral contraceptive.
Carbohydrate metabolism was prospectively evaluated in twenty-one normal women prior to and during their use for three months of a monophasic oral contraceptive containing the progestin gestodene plus ethinyl estradiol. The women had a three-hour oral glucose tolerance test using a 75 gram glucose load, measuring serum glucose and insulin levels. The results demonstrate no significant changes in either of the carbohydrate metabolic indices between the two tests. These data support the safety of this new progestin-containing contraceptive.
Spellacy
W N
WN
Department of Obstetrics and Gynecology, University of South Florida College of Medicine, Tampa 33606.
Schwandt
R A
RA
Tsibris
J C
JC
Smalling
S
S
Chez
R A
RA
Angel
J L
JL
O'Brien
W F
WF
D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D050260:Carbohydrate Metabolism; D003276:Contraceptives, Oral / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D009652:Norpregnenes / Q000494:pharmacology*; D011446:Prospective Studies
D001786:Blood Glucose; D003276:Contraceptives, Oral; D007328:Insulin; D009652:Norpregnenes; C033273:Gestodene