Craniovascular nociceptive pathways relay in the upper cervical spinal cord in the cat.
Units in the dorsolateral area of the upper cervical cord and the ventroposteromedial nucleus of the thalamus respond to stimulation of cranial vessels. To study the physiological role of the upper cervical cord in craniovascular transmission, we used a cryoprobe to interrupt reversibly neural transmission through the cord while recording in the thalamus. Twenty-one of 47 thalamic units tested showed reversible diminution in their response to superior sagittal sinus stimulation during cervical cord cooling. In contrast, receptive field responses and spontaneous thalamic activity were unaffected. These data suggest offt the cervical cord relays craniovascular nociceptive afferents.
Angus-Leppan
H
H
Institute of Neurological Sciences, Prince Henry Hospital, New South Wales, Australia.
Lambert
G A
GA
Boers
P
P
Zagami
A S
AS
Olausson
B
B
D000818:Animals; D002415:Cats; D009434:Neural Pathways / Q000502:physiology; D009619:Nociceptors / Q000502:physiology*; D013116:Spinal Cord / Q000166:cytology / Q000502:physiology*; D013788:Thalamus / Q000502:physiology; D013816:Thermodynamics