Epilepsy as the presenting feature of neuroacanthocytosis in siblings.
A brother and sister developed epilepsy at the age of 28 and 30 years respectively, and were subsequently found to have neuroacanthocytosis. The brother developed tics, and a tendency to self-mutilate a year later, but his sister had not developed any movement disorder in the 5 years since the onset of epilepsy. In families with epilepsy, the diagnosis of neuroacanthocytosis should be considered, particularly when one family member has tics or other involuntary movements.
Schwartz
M S
MS
Department of Neurology, Atkinson Morley's Hospital, London, UK.
Monro
P S
PS
Leigh
P N
PN
D000328:Adult; D004827:Epilepsy / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D009069:Movement Disorders / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D009132:Muscles / Q000503:physiopathology; D009431:Neural Conduction / Q000502:physiology; D011930:Reaction Time / Q000502:physiology