[Renal tuberculosis treated with rifampicin, isoniazid and ofloxacin].
We describe the results of eight patients with renal tuberculosis treated with rifampin, isoniazid and ofloxacin. Ofloxacin was given orally, 200 mg b.i.d. for 6 months. During the first three months, rifampin (600 mg/daily) and isoniazid (330 mg/daily) were added. All M. tuberculosis strains isolated were sensitive to ofloxacin (MIC 1 mg/l). Follow-up cultures turned to be negative rapidly (during the first month of therapy), and no untoward effects were recorded. All patients had a 12-months follow-up period, and all were clinically cured. The treatment used was well accepted by all patients.
Alberte
A
A
Servicios de Microbiología, Hospital del Río Hortega, Valladolid.
Martínez-Sagarra
J M
JM
Estébanez
M J
MJ
Pascual
P P
PP
D000293:Adolescent; D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000008:administration & dosage / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D015242:Ofloxacin / Q000008:administration & dosage / Q000627:therapeutic use*; D012293:Rifampin / Q000008:administration & dosage / Q000627:therapeutic use; D014398:Tuberculosis, Renal / Q000188:drug therapy*
D000995:Antitubercular Agents; D015242:Ofloxacin; D007538:Isoniazid; D012293:Rifampin
Tratamiento de la tuberculosis renal con rifampicina, isoniazida y ofloxacino.