title: [Burkitt's lymphoma with granulocytosis and a high level of C-reactive protein].
abstract: A case of Burkitt's lymphoma with granulocytosis including immature cells and a high level of C-reactive protein (CRP) is reported. The activity of interleukin-1 alpha (IL-1 alpha) was detected in the sera, although its activity was not detected in the supernate of the cultured lymphoblasts. The lymphoblasts stimulated production of IL-1 alpha from human umbilical endothelial cells. Therefore, the lymphoblasts infiltrating bone marrow may have stimulated production of IL-1 alpha from bone marrow stroma cells, and IL-1 alpha may have induced granulocytosis and a high level of CRP.
authors.affiliation: Department of Medicine, Jichi Medical School.
authors.forename: K
authors.initials: K
authors.lastname: Muroi
authors.forename: T
authors.initials: T
authors.lastname: Izumi
authors.forename: M
authors.initials: M
authors.lastname: Yoshida
authors.forename: T
authors.initials: T
authors.lastname: Suda
authors.forename: A
authors.initials: A
authors.lastname: Miwa
authors.forename: S
authors.initials: S
authors.lastname: Sakamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Miura
mesh_terms: D000368:Aged; D002051:Burkitt Lymphoma / Q000097:blood* / Q000150:complications; D002097:C-Reactive Protein / Q000032:analysis*; D006098:Granulocytes; D006801:Humans; D007964:Leukocytosis / Q000150:complications*; D008297:Male
chemical_list: D002097:C-Reactive Protein