[Synthesis of metabolites and enantiomers of prolintane].
The synthesis of 15 possible metabolites of prolintane (1) (Katovit) which is used in the treatment of blood pressure disregulations is described. Furthermore, the preparation of the enantiomers of 1 is reported, starting with R-(+)- and S-(-)-phenylalaninol respectively.
Rücker
G
G
Pharmazeutisches Institut, Universität Bonn.
Neugebauer
M
M
Zhong
D
D
D011759:Pyrrolidines / Q000737:chemistry / Q000378:metabolism*; D013237:Stereoisomerism
D011759:Pyrrolidines; C005598:prolintane
Synthese einiger Metaboliten und der Enantiomeren des Prolintans.