title: Hypoprothrombinemia secondary to administration of sulfaquinoxaline to dogs in a kennel setting.
abstract: Sulfaquinoxaline, a coccidiostat readily available to the public, was mixed in the drinking water for this purpose by the owner. Secondary to its use, a bleeding disorder attributable to hypoprothrombinemia developed in several dogs. Clinical signs of bleeding ceased 24 hours after institution of vitamin K1 and discontinuation of sulfaquinoxaline in the drinking water. This report should remind veterinarians that drugs and medications readily available to the public may have adverse effects in animals, and such problems should be investigated whenever multiple dogs in a common setting are affected with the same clinical problem.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine, Louisiana State University, Baton Rouge 70803.
authors.forename: T M
authors.initials: TM
authors.lastname: Neer
authors.forename: R L
authors.initials: RL
authors.lastname: Savant
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000139:chemically induced*; D004285:Dogs; D004326:Drinking; D005260:Female; D007020:Hypoprothrombinemias / Q000139:chemically induced / Q000662:veterinary*; D013428:Sulfaquinoxaline / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D013428:Sulfaquinoxaline