title: Nutrient intake and biochemical markers of nutritional status during long-term follow-up after total and partial gastrectomy.
abstract: Dietary intake and biochemical nutritional status was studied in patients who had undergone total gastrectomy (TG, n = 10) or partial gastrectomy (PG, n = 10) several years ago. The dietary intake of energy, macronutrients and micronutrients was very similar in the two groups and was also similar to the intake reported for healthy subjects in Sweden. The concentration of alpha-tocopherol in serum was subnormal in the TG group and that of carotene in both groups of patients, and the values were also significantly lower in the TG group than in the PG group. This was probably due to fat malabsorption, since dietary intake was found to be adequate. The proportions of n-6 and n-3 polyunsaturated fatty acids in serum phosphatidylcholine were not significantly different between the TG and PG groups. Iron deficiency was found in three patients in the TG group. Three patients (two TG, one PG) had elevated serum alkaline phosphatase and one patient (PG) had subnormal cobalamin concentration. For ascorbic acid, folate, calcium, phosphorus, magnesium, zinc, copper and selenium, the serum concentrations were normal or close to normal. Although the stores of some micronutrients seemed smaller after total gastrectomy, no major differences in nutritional status were found between the TG and PG groups. For the demonstration of decreased micronutrient stores during long-term follow-up after gastrectomy, an extended profile of biochemical markers of nutritional status is recommended.
authors.affiliation: Department of Surgery, University of Lund, Sweden.
authors.forename: C
authors.initials: C
authors.lastname: Staël von Holstein
authors.forename: E
authors.initials: E
authors.lastname: Ibrahimbegovic
authors.forename: B
authors.initials: B
authors.lastname: Walther
authors.forename: B
authors.initials: B
authors.lastname: Akesson
mesh_terms: D015415:Biomarkers / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D008286:Malabsorption Syndromes / Q000097:blood / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D015596:Nutrition Assessment; D009749:Nutrition Surveys; D009752:Nutritional Status; D013548:Sweden / Q000453:epidemiology
chemical_list: D015415:Biomarkers