Glucose-6-phosphate dehydrogenase deficiency and sulfadimidin acetylation phenotypes in Egyptian oases.
Screening of 1315 males from two Egyptian oases for glucose-6-phosphate dehydrogenase deficiency (G-6PD) found an incidence of 5.9%. The rate of acetylation of sulfadimidin was also studied, and a bimodal distribution was found with 73% rapid acetylators. There is a correlation between high frequency of G-6PD deficiency and high frequency of slow acetylation rate.
Hussein
L
L
Nutrition Laboratory, National Research Centre, Giza, Egypt.
Yamamah
G
G
Saleh
A
A
D000107:Acetylation; D002648:Child; D002675:Child, Preschool; D004534:Egypt; D005787:Gene Frequency; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000097:blood* / Q000453:epidemiology / Q000235:genetics; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010641:Phenotype; D011110:Polymorphism, Genetic; D013418:Sulfamethazine / Q000097:blood*
D013418:Sulfamethazine