Some possible gynaecological indications for peripheral antidopamine therapy.
The effect of the dopamine receptor blocking domperidone (Motilium) has been examined in 73 gynaecological patients in a wide indication field. The treatment was successful in controlling dyspeptic symptoms of different origins, nausea-vomiting of different etiologies, climacteric flushes, and in the prevention of migraines in 67.1% of the cases. Partial response was obtained in 19.2%, and no response in 13.7% of the cases. According to the opinion of the authors the gastrokinetic and antiemetic effect of domperidone is of high value, the use of the drug may be attempted as a monotherapy or an adjuvant therapy for the prevention of migraine and the treatment of climacteric flushes.
Varga
A
A
Second Department of Obstetric and Gynaecology, Municipal János Hospital-Outpatient Clinic.
Lovas
J
J
D000328:Adult; D002979:Climacteric / Q000187:drug effects*; D004294:Domperidone / Q000627:therapeutic use*; D004341:Drug Evaluation; D004415:Dyspepsia / Q000188:drug therapy; D005260:Female; D005767:Gastrointestinal Diseases / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D008881:Migraine Disorders / Q000517:prevention & control*; D009325:Nausea / Q000517:prevention & control; D011183:Postoperative Complications / Q000517:prevention & control; D014839:Vomiting / Q000517:prevention & control
D004294:Domperidone