title: A noninvasive test of sphincter of Oddi dysfunction in postcholecystectomy patients: the scintigraphic score.
abstract: The ideal noninvasive test of sphincter of Oddi dysfunction (SOD) does not exist and the diagnosis of patients with postcholecystectomy pain often relies on invasive procedures. In this paper we describe a scintigraphic test for SOD: the scintigraphic score. This score combines quantitative and visual criteria for interpretation of hepatobiliary scans. Twenty-six consecutive postcholecystectomy patients underwent hepatobiliary imaging, ERCP, and sphincter manometry. Twelve patients had SOD and 14 had normal sphincters determined by clinical findings, ERCP, and manometric studies. All patients with normal sphincter had scores of 0-4, while patients with SOD had values of 5-12 for a perfect sensitivity and specificity of 100%. Hepatobiliary scans scored in this fashion may become the noninvasive test of choice to screen postcholecystectomy patients with suspected SOD.
authors.affiliation: Division of Nuclear Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland 21205.
authors.forename: S
authors.initials: S
authors.lastname: Sostre
authors.forename: A N
authors.initials: AN
authors.lastname: Kalloo
authors.forename: E J
authors.initials: EJ
authors.lastname: Spiegler
authors.forename: E E
authors.initials: EE
authors.lastname: Camargo
authors.forename: H N
authors.initials: HN
authors.lastname: Wagner
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002763:Cholecystectomy; D002766:Cholecystokinin; D003137:Common Bile Duct Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000453:epidemiology; D005260:Female; D006801:Humans; D007098:Imino Acids; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D010149:Postoperative Pain / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology*; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D009803:Sphincter of Oddi; D019785:Technetium Tc 99m Disofenin
chemical_list: D007098:Imino Acids; D015609:Organotechnetium Compounds; D002766:Cholecystokinin; D019785:Technetium Tc 99m Disofenin