title: Unusual physiologic melanin pigmentation of the tongue.
abstract: A patient had extensive congenital oral hyperpigmentation of the tongue. The clinical and histologic features set this case apart from any well-delineated disease. Clinically, the congenital onset, the appearance of large black-brownish lesions, the lack of associated systemic abnormalities, and the histologic findings of prominent deposition of melanin in the basal layer support the diagnosis of physiologic melanosis. The macular lesions of the tongue represent discrete depositions of melanin and exemplify soft tissue pigmentation of developmental origin.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Beilinson Medical Center, Petah Tiqva, Israel.
authors.forename: Y
authors.initials: Y
authors.lastname: Anavi
authors.forename: S
authors.initials: S
authors.lastname: Mintz
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008543:Melanins / Q000032:analysis; D008545:Melanoma / Q000473:pathology; D008548:Melanosis / Q000151:congenital* / Q000473:pathology; D009508:Nevus, Pigmented / Q000473:pathology; D014060:Tongue Diseases / Q000151:congenital* / Q000473:pathology; D014062:Tongue Neoplasms / Q000473:pathology
chemical_list: D008543:Melanins