title: Dismantling the pyramid.
abstract: The suggestion is heard, with increasing frequency, that the therapeutic pyramid be dismantled and that medical management be reordered to treat juvenile rheumatoid arthritis as early and as decisively as possible to induce prompt remission of disease, thereby preserving function and the quality of life. We scrutinize paradigms that guide our treatment strategies, review current practices, update data derived from those practices, and propose reassessment for treatment in the 1990s.
authors.affiliation: Department of Pediatrics, University of Cincinnati, Children's Hospital Medical Center, OH 45229-2899.
authors.forename: J E
authors.initials: JE
authors.lastname: Levinson
authors.forename: C A
authors.initials: CA
authors.lastname: Wallace
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001171:Arthritis, Juvenile / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D001175:Arthrography; D002675:Child, Preschool; D015331:Cohort Studies; D006801:Humans; D016019:Survival Analysis
chemical_list: D000893:Anti-Inflammatory Agents