Movement disorders as sequelae of central pontine myelinolysis: report of three cases.
In three survivors of central pontine myelinolysis, dystonia (in two patients) and rest tremor (in one) were sequelae. The onset of these movements occurred 3 weeks to 5 months after the initial presentation with central pontine myelinolysis. Magnetic resonance imaging revealed basal ganglia lesions suggestive of extra-pontine myelinolysis in all three patients. We propose that the movement disorders seen in our cases are clinical correlates of extra-pontine myelinolysis.
Maraganore
D M
DM
Department of Neurology, Mayo Clinic, Rochester, MN 55905.
Folger
W N
WN
Swanson
J W
JW
Ahlskog
J E
JE
D003711:Demyelinating Diseases / Q000139:chemically induced* / Q000175:diagnosis; D004630:Emergencies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007010:Hyponatremia / Q000175:diagnosis / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009460:Neurologic Examination / Q000187:drug effects; D011149:Pons / Q000187:drug effects* / Q000473:pathology; D011699:Putamen / Q000187:drug effects / Q000473:pathology; D011782:Quadriplegia / Q000139:chemically induced* / Q000175:diagnosis; D012462:Saline Solution, Hypertonic / Q000008:administration & dosage / Q000009:adverse effects*
D012462:Saline Solution, Hypertonic