title: [Effectiveness and tolerance of tramadol with or without an antiemetic and pethidine in obstetric analgesia].
abstract: The aim of this prospective, randomised, blind study was to investigate the analgesic potency and tolerance of intramuscular Tramadol compared to a standard obstetric analgesia with Pethidine. Triflupromazine was administrated in combination with the two tested analgesics in order to study its efficacy in alleviating the emetic side effects of the tested analgesics. 66 parturients were randomly assigned to three groups: group A: 100 mg Tramadol (Tramal), group B: 100 mg Tramadol (Tramal) and 10 mg Triflupromazine (Psyquil), group C: 50 mg Pethidine (Alodan) and 10 mg Triflupromazine (Psyquil). No significant differences concerning duration of labour, FHR-alterations, umbilical cord blood gases, respiration pattern and Apgar Scores of the neonate occurred. In all three groups the analgesic effect was equally good. Combination of the analgesic with the antiemetic showed no reduction of the incidence and severity of side effects.
authors.affiliation: II. Universitäts-Frauenklinik Wien.
authors.forename: C
authors.initials: C
authors.lastname: Kainz
authors.forename: E
authors.initials: E
authors.lastname: Joura
authors.forename: R
authors.initials: R
authors.lastname: Obwegeser
authors.forename: B
authors.initials: B
authors.lastname: Plöckinger
authors.forename: W
authors.initials: W
authors.lastname: Gruber
mesh_terms: D000328:Adult; D016362:Analgesia, Obstetrical / Q000379:methods*; D015148:Cardiotocography / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007273:Injections, Intramuscular; D008614:Meperidine / Q000008:administration & dosage* / Q000009:adverse effects; D010121:Oxytocin / Q000008:administration & dosage; D010147:Pain Measurement; D011247:Pregnancy; D011446:Prospective Studies; D014147:Tramadol / Q000008:administration & dosage* / Q000009:adverse effects; D014273:Triflupromazine / Q000008:administration & dosage* / Q000009:adverse effects; D014590:Uterine Contraction / Q000187:drug effects
chemical_list: D014147:Tramadol; D010121:Oxytocin; D008614:Meperidine; D014273:Triflupromazine
vernacular_title: Wirksamkeit und Verträglichkeit von Tramadol mit oder ohne Antiemetikum sowie von Pethidin zur geburtshilflichen Analgesie.