Immunologic abnormalities in myelodysplastic syndromes.
In myelodysplastic syndromes, several autoimmune phenomena are more common than expected. Lymphocyte subsets are sometimes abnormal in number and function. Associated lymphoid malignancies and lymphoblastic evolution have occasionally been reported. Molecular studies suggest that the lymphoid system may be involved in the dysplastic process.
Hamblin
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Department of Immunohaematology, Southampton University, United Kingdom.
D001327:Autoimmune Diseases / Q000150:complications / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology / Q000473:pathology; D006801:Humans; D007239:Infections / Q000150:complications; D007694:Killer Cells, Natural / Q000276:immunology / Q000473:pathology; D009000:Monocytes / Q000276:immunology / Q000473:pathology; D009190:Myelodysplastic Syndromes / Q000150:complications / Q000276:immunology* / Q000473:pathology; D009369:Neoplasms / Q000150:complications; D013601:T-Lymphocytes / Q000276:immunology / Q000473:pathology