title: Disorders of smooth pursuit eye movement and auditory N100 in schizophrenic patients.
abstract: Attentional factors are thought to affect eye-tracking patterns. The present study examined the hypothesis that specific quantitative features of eye tracking would be correlated with the amplitude of a component of the auditory evoked potential, the N100, which is known to be enhanced by arousal and selective attention. We studied 12 clinically stable schizophrenic patients by means of DC-electro-oculography. The frequency and amplitude of different types of saccades (catchup, backup, anticipatory saccades, and square wave jerks) were assessed. The results suggest that small and large saccades, as classified by a simple amplitude criterion (4 degrees), have differential meanings and indicate that enhanced amplitudes of small saccades are an effect of arousal.
authors.affiliation: Department of Psychiatry, University of Würzburg, Germany.
authors.forename: W K
authors.initials: WK
authors.lastname: Strik
authors.forename: T
authors.initials: T
authors.lastname: Dierks
authors.forename: J
authors.initials: J
authors.lastname: Böning
authors.forename: M
authors.initials: M
authors.lastname: Osterheider
authors.forename: A
authors.initials: A
authors.lastname: Caspari
authors.forename: J
authors.initials: J
authors.lastname: Körber
mesh_terms: D000328:Adult; D000368:Aged; D001143:Arousal / Q000502:physiology*; D001288:Attention / Q000502:physiology*; D002540:Cerebral Cortex / Q000503:physiopathology; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011698:Pursuit, Smooth / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D012438:Saccades / Q000502:physiology; D012559:Schizophrenia / Q000175:diagnosis / Q000503:physiopathology*; D012565:Schizophrenic Psychology