title: Short-term outcome in infants with birth weights less than 1750 g born to mothers with HELLP syndrome.
abstract: Premature infants born to mothers with HELLP syndrome were reported to have a less favourable outcome compared to infants with uncomplicated maternal history. We investigated the short term outcome in 21 premature infants with birth weights less than 1750 g born to mothers with HELLP syndrome. Median birth weight was 1050 g (range 420 g-1750 g), corresponding gestational age 29 weeks (range 26-35 weeks). Mechanical ventilation for RDS was necessary in 15 infants. Intracranial hemorrhage was diagnosed in 2 infants, 1 of the surviving infants developed bronchopulmonary dysplasia. Acute renal failure was observed in 3 infants immediately after birth. Mortality was attributed to progressive respiratory failure in 2 patients (b.w. 420 g and 490 g) and persisting acute renal failure in 1 patient (b.w. 520 g) Leucocytopenia (less than 9000/mm3) was observed in 13 infants and thrombocytopenia (less than 115000/mm3) was noted in 4 infants during the first day. Eighteen infants survived. We conclude, that the short term outcome in infants born to mothers with HELLP syndrome is not as poor, as previously reported.
authors.affiliation: Children's Hospital, Fed. Rep. of Germany.
authors.forename: L
authors.initials: L
authors.lastname: Gortner
authors.forename: F
authors.initials: F
authors.lastname: Pohlandt
authors.forename: P
authors.initials: P
authors.lastname: Bartmann
authors.forename: R
authors.initials: R
authors.lastname: Terinde
authors.forename: H
authors.initials: H
authors.lastname: Versmold
authors.forename: O
authors.initials: O
authors.lastname: Dorigo
mesh_terms: D001724:Birth Weight; D005260:Female; D005865:Gestational Age; D006461:Hemolysis; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D007234:Infant, Premature; D008099:Liver / Q000201:enzymology*; D011225:Pre-Eclampsia / Q000150:complications*; D011247:Pregnancy; D011248:Pregnancy Complications; D011379:Prognosis; D012189:Retrospective Studies; D013577:Syndrome; D013921:Thrombocytopenia / Q000150:complications*