Characterization of p30, a highly antigenic membrane and secreted protein of African swine fever virus.
We have identified and characterized a 30-kDa phosphoprotein (p30) of African Swine Fever Virus (ASFV) that is synthesized, membrane localized, and released into the culture medium at early times after infection. Sequence analysis of the p30 open reading frame predicts a highly antigenic protein with putative phosphorylation, glycosylation, and membrane attachment sites.
Afonso
C L
CL
Plum Island Animal Disease Center, United States Department of Agriculture, Greenport, New York 11944.
Alcaraz
C
C
Brun
A
A
Sussman
M D
MD
Onisk
D V
DV
Escribano
J M
JM
Rock
D L
DL
D000358:African Swine Fever Virus / Q000235:genetics* / Q000276:immunology; D000595:Amino Acid Sequence; D000818:Animals; D000911:Antibodies, Monoclonal; D000956:Antigens, Viral / Q000096:biosynthesis / Q000235:genetics* / Q000276:immunology; D001483:Base Sequence; D002478:Cells, Cultured; D006031:Glycosylation; D008264:Macrophages / Q000382:microbiology; D008565:Membrane Proteins / Q000235:genetics / Q000276:immunology / Q000378:metabolism; D008969:Molecular Sequence Data; D010750:Phosphoproteins / Q000235:genetics* / Q000276:immunology / Q000378:metabolism; D010766:Phosphorylation; D011487:Protein Conformation; D013552:Swine; D014764:Viral Proteins / Q000235:genetics* / Q000276:immunology / Q000378:metabolism
D000911:Antibodies, Monoclonal; D000956:Antigens, Viral; D008565:Membrane Proteins; D010750:Phosphoproteins; D014764:Viral Proteins; C074960:P30 protein, African Swine Fever Virus