Embryonal rhabdomyosarcoma with 100 chromosomes but no structural aberrations.
An embryonal rhabdomyosarcoma was analyzed cytogenetically after short-term culturing. The tumor was located in the scrotum of an 18-year-old man who, at the age of 4, had been treated for a rhabdomyosarcoma in the orbita. The chromosome number was 100. No structural aberrations were present. There were 2-7 copies of each chromosome type with particular excess of chromosomes 8, 12, and 22, and a relative deficit of chromosome 15.
Olegård
C
C
Department of Clinical Genetics, University Hospital, Lund, Sweden.
Mandahl
N
N
Heim
S
S
Willén
H
H
Leifsson
B
B
Mitelman
F
F
D000293:Adolescent; D002869:Chromosome Aberrations; D005834:Genital Neoplasms, Male / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007621:Karyotyping; D008297:Male; D012208:Rhabdomyosarcoma / Q000235:genetics* / Q000473:pathology; D012611:Scrotum / Q000473:pathology*