Odor-induced fos-like immunoreactivity in the rat olfactory bulb.
We here report odor-induced mapping patterns of c-fos-like protein (Fos) immunoreactivity in the rat olfactory bulb under urethane anesthesia. Regional patterns of cells with nuclei expressing Fos, plotted on a spread-out reconstruction of the mitral cell layer, were strikingly comparable to data from the 2-deoxyglucose method, by which different foci of the most-labelled glomeruli of metabolic activity were demonstrated using different odors. Cells in the glomerular, external plexiform, and granule cell layers were also labelled.
Onoda
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Department of Physiology, School of Medicine, Gunma University, Maebashi, Japan.
D000818:Animals; D002628:Chemoreceptor Cells / Q000502:physiology; D003847:Deoxyglucose; D007150:Immunohistochemistry; D008297:Male; D009474:Neurons / Q000502:physiology; D009812:Odorants; D009830:Olfactory Bulb / Q000033:anatomy & histology / Q000166:cytology / Q000502:physiology*; D016760:Proto-Oncogene Proteins c-fos / Q000276:immunology / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
D016760:Proto-Oncogene Proteins c-fos; D003847:Deoxyglucose