Precautions when using methoxyflurane.
Methoxyflurane has a high blood/gas partition coefficient and a low vapor pressure. Mask inductions may be excessively slow, necessitating early high vaporizer control knob settings or additional injectable induction agent. Recoveries may be very prolonged. Methoxyflurane is extensively metabolized, and this may be associated with hepatotoxicity and nephrotoxicity.
Dyson
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Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Canada.
D000769:Anesthesia, Inhalation / Q000662:veterinary*; D000818:Animals; D004285:Dogs / Q000502:physiology*; D006439:Hemodynamics / Q000187:drug effects; D007668:Kidney / Q000187:drug effects*; D008099:Liver / Q000187:drug effects*; D008733:Methoxyflurane / Q000009:adverse effects*
D008733:Methoxyflurane