Differential effect of castration on the somal size of pudendal motoneurons in the adult male rat.
We have examined the organization of the androgen sensitivity of pudendal motoneurons in adult male rats. Comparisons of mean somal cross sectional area of pudendal motoneurons identified by retrograde labeling with horseradish peroxidase were made between three treatment groups: castrates with testosterone propionate supplementation, castrates with placebo, and sham castrates. Bulbospongiosus and ischiocavernosus motoneurons were sensitive to androgen treatment, whereas external anal sphincter and external urethral sphincter motoneurons were not.
Collins
W F
WF
Department of Neurobiology and Behavior, State University of New York, Stony Brook 11794-5230.
Seymour
A W
AW
Klugewicz
S W
SW
D000818:Animals; D006735:Horseradish Peroxidase; D008297:Male; D009046:Motor Neurons / Q000166:cytology* / Q000187:drug effects; D009919:Orchiectomy; D010413:Penis / Q000294:innervation*; D051381:Rats; D011919:Rats, Inbred Strains; D013737:Testis / Q000502:physiology*; D013739:Testosterone / Q000494:pharmacology*
D013739:Testosterone; D006735:Horseradish Peroxidase