title: [Neonatal malignant tumors. Apropos of 75 cases].
abstract: From 1975 to 1986, 75 neonates were treated at the Institute Gustave-Roussy for a malignant solid tumor, comprising 1.7% of the overall oncopediatric population treated during the same period of time. Of these 75 patients, 47 (62%) presented with neuroblastomas, 15 (20%) with mesenchymal tumors, 9 (12%) with germ cell tumors and 4 with various other types of tumors. Treatment consisted of surgery in 63 patients, chemotherapy in 43 and radiotherapy in 18. The 5 year crude survival rate was 77%. Neuroblastomas did the best with a crude survival rate of 89%. The young age of the patients resulted in two types of problems: immediate tolerance and long term sequelae. The therapeutic regimen should take into account the good prognosis of the majority of these tumors in order to decrease delayed effects.
authors.affiliation: Service d'Oncologie Pédiatrique, Institut Gustave-Roussy, Villejuif.
authors.forename: C
authors.initials: C
authors.lastname: Teinturier
authors.forename: C
authors.initials: C
authors.lastname: Kalifa
authors.forename: O
authors.initials: O
authors.lastname: Hartmann
authors.forename: F
authors.initials: F
authors.lastname: Flamant
authors.forename: J
authors.initials: J
authors.lastname: Lemerle
mesh_terms: D000008:Abdominal Neoplasms / Q000401:mortality / Q000628:therapy*; D000310:Adrenal Gland Neoplasms / Q000401:mortality / Q000628:therapy*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001859:Bone Neoplasms / Q000401:mortality / Q000628:therapy*; D003131:Combined Modality Therapy; D005134:Eye Neoplasms / Q000401:mortality / Q000628:therapy; D005260:Female; D006393:Hemangiopericytoma / Q000401:mortality / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D007680:Kidney Neoplasms / Q000401:mortality / Q000628:therapy; D008297:Male; D009447:Neuroblastoma / Q000401:mortality / Q000628:therapy*; D012175:Retinoblastoma / Q000401:mortality / Q000628:therapy; D012208:Rhabdomyosarcoma / Q000401:mortality / Q000628:therapy*; D012509:Sarcoma / Q000401:mortality / Q000628:therapy; D013724:Teratoma / Q000401:mortality / Q000628:therapy; D013736:Testicular Neoplasms / Q000401:mortality / Q000628:therapy
vernacular_title: Tumeurs solides malignes néonatales. A propos de 75 cas.