Effect of intraumbilical prostaglandin F2 alpha injection on the third stage of labor.
The effect of an intraumbilical prostaglandin (PG) F2 alpha injection on the third stage of normal labor was studied in 54 normal, laboring women at term. Either 1 mg of PGF2 alpha diluted to 20 mL in normal saline (27 women) or 20 mL of normal saline alone (27 women) was injected into the umbilical vein immediately after delivery using a randomized, double-blind protocol. The mean (+/- SD) duration of the third stage was 7.31 +/- 6.37 minutes in the PGF2 alpha patients and 8.94 +/- 7.10 in the normal saline patients. Intraumbilical PGF2 alpha did not influence the third stage of normal labor.
Bider
D
D
Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Ben-Rafael
Z
Z
Dulitzky
M
M
Menashe
Y
Y
Mashiach
S
S
Barkai
G
G
D000328:Adult; D001724:Birth Weight; D001827:Body Height; D001835:Body Weight; D015237:Dinoprost / Q000008:administration & dosage / Q000494:pharmacology*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D007749:Labor Stage, Third / Q000187:drug effects*; D009035:Mothers; D010298:Parity; D011247:Pregnancy; D012744:Sex Ratio; D013997:Time Factors; D014471:Umbilical Veins
D015237:Dinoprost