Genotoxic effect of smoke-dried meat extract in Swiss albino mice using sperm head shape abnormality test.
The genotoxic effect of an extract of smoke-dried meat was assayed by employing in vivo sperm head shape abnormality. A significant dose responsive mutagenic effect was observed using the sperm head shape abnormality test. The result indicates that higher doses i.e., 100 and 200 mg/kg body wt. of smoke meat extract, significantly induced sperm head shape abnormality as compared to lower doses i.e., 20 mg/kg body wt. and control.
Kumar
S
S
Division of Cancer Biology, Regional Medical Centre, Assam, India.
Zinyu
R
R
Chetia
M
M
Dutta
L P
LP
D000818:Animals; D007194:India; D008297:Male; D008460:Meat / Q000032:analysis*; D051379:Mice; D009152:Mutagenicity Tests; D009153:Mutagens / Q000302:isolation & purification / Q000494:pharmacology; D009303:Nasopharyngeal Neoplasms / Q000453:epidemiology / Q000209:etiology; D012906:Smoke; D013077:Sperm Head / Q000187:drug effects / Q000648:ultrastructure*; D014020:Tissue Extracts / Q000032:analysis
D009153:Mutagens; D012906:Smoke; D014020:Tissue Extracts