[Histoautoradiographic characteristics of candidiasis pneumonia in combination drug therapy].
The lungs and organs of guinea pigs infected with fungus Candida against the background of cyclophosphamide immunodeficiency and therapy with antibiotics were studied morphologically. Secondary immunodeficiency and dysbacteriosis are shown to influence considerably the ability of fungal cells to utilize DNA and RNA precursors (tritium-labelled thymidine and uridine). Historadioautography allowed one to evaluate functional state of the infectious agent and host cell responses.
Khmel'nitskiĭ
O K
OK
Kotovich
V M
VM
Kolokol'chikova
E G
EG
D000818:Animals; D000900:Anti-Bacterial Agents; D001345:Autoradiography; D002177:Candidiasis / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D003520:Cyclophosphamide / Q000627:therapeutic use; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D006168:Guinea Pigs; D011014:Pneumonia / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D013936:Thymidine / Q000378:metabolism; D014529:Uridine / Q000378:metabolism
D000900:Anti-Bacterial Agents; D003520:Cyclophosphamide; D013936:Thymidine; D014529:Uridine
Gistoavtoradiograficheskaia kharakteristika kandidoznĭ pnevmonii pri kombinirovannom lekarstvennom vozdeĭstvii.