title: Development of spontaneous echocardiographic contrast after surgical trauma.
abstract: To determine if hypercoagulability is associated with contrast, surgical trauma was studied in a canine model. Contrast increased in the right heart and aorta after laparotomy, but not after anesthesia alone in either the right or the left heart. The inferior vena cava had the largest amount of contrast after surgery, implying that contrast development was primarily a local response to injury. The cellular composition of this contrast was not determined, but it occurred in the absence of changes in systemic rheologic or hematologic parameters and was not affected by heparin administration.
authors.affiliation: Wenner-Gren Research Laboratory, Department of Biomedical Engineering, University of Kentucky, Lexington 40506-0701.
authors.forename: C
authors.initials: C
authors.lastname: Mahony
authors.forename: J M
authors.initials: JM
authors.lastname: Ferguson
mesh_terms: D000771:Anesthesia, Intravenous / Q000009:adverse effects; D000818:Animals; D001778:Blood Coagulation Disorders / Q000000981:diagnostic imaging / Q000209:etiology*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D004285:Dogs; D004452:Echocardiography; D006325:Heart Atria / Q000601:surgery; D006352:Heart Ventricles / Q000601:surgery; D014682:Vena Cava, Inferior / Q000000981:diagnostic imaging