[A control study of intravenous versus oral clomipramine in major depression].
Intravenous clomipramine (n = 105) and oral clomipramine (n = 64) were compared in a control study of 169 inpatients with major depression. The therapeutic effects were evaluated with four-degree scale and the rating scales of HDS and CGI. The results showed intravenous group has earlier response and better antidepressive effects than oral group within treatment period of 2 weeks. No significant differences between two groups were found in anticholinergic side-reaction. Clinical useful values of intravenous clomipramine were discussed.
Zhao
J
J
Mental Health Institute of Hunan Medical University, Changsha.
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D002997:Clomipramine / Q000008:administration & dosage* / Q000009:adverse effects; D003866:Depressive Disorder / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D013607:Tablets
D013607:Tablets; D002997:Clomipramine