title: Total lymphoid irradiation in chronic progressive multiple sclerosis.
abstract: 6 patients with severe chronic progressive multiple sclerosis were subjected to total lymphoid irradiation (TLI) to assess clinical efficacy and side effects. During a 4 year follow-up the disability progression was continuous. Side effects during TLI were well tolerated; side effects after TLI brought about a worsening of the quality of life. One patient died of pneumonia. In this preliminary study TLI did not reduce the worsening of disability in MS patients.
authors.affiliation: Clinica Neurologica, Università di Brescia.
authors.forename: R
authors.initials: R
authors.lastname: Capra
authors.forename: N
authors.initials: N
authors.lastname: Marcianó
authors.forename: F
authors.initials: F
authors.lastname: Mattioli
authors.forename: V
authors.initials: V
authors.lastname: Di Monda
authors.forename: L A
authors.initials: LA
authors.lastname: Vignolo
authors.forename: A
authors.initials: A
authors.lastname: Buffoli
authors.forename: E
authors.initials: E
authors.lastname: Micheletti
authors.forename: L
authors.initials: L
authors.lastname: Magno
mesh_terms: D000328:Adult; D002908:Chronic Disease; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008208:Lymphatic System; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000503:physiopathology / Q000532:radiotherapy*