title: [Anesthesiologic aspects of multiorgan donation].
abstract: As of July 1990 brain death was legally recognized in Denmark thereby rendering transplantation of heart, liver and lung possible. Brain death donors are usually treated in neurosurgical or anaesthetic intensive care units. The staff of these units influence the number of donors and also the quality of organs donated. Physiological factors pertinent to brain death donors and pre- and peroperative donor therapy in relation to multiorgan procurement are discussed from the viewpoint of the anaesthetist. Symptomatic therapy aimed at optimizing and maintaining organ function is employed; thus continuing intensive care. Sympathetic and somatic reflex responses to surgical stimulation are to be anticipated, often necessitating analgesics to blunt haemodynamic responses and neuromuscular blocking agents to inhibit movements and/or rigidity.
authors.affiliation: Anaestesiafdelingen, Rigshospitalet, København.
authors.forename: P B
authors.initials: PB
authors.lastname: Hansen
authors.forename: B K
authors.initials: BK
authors.lastname: Thisted
authors.forename: L W
authors.initials: LW
authors.lastname: Andersen
authors.forename: B
authors.initials: B
authors.lastname: Larsen
authors.forename: E C
authors.initials: EC
authors.lastname: Jansen
authors.forename: N H
authors.initials: NH
authors.lastname: Secher
mesh_terms: D000777:Anesthetics / Q000008:administration & dosage*; D001926:Brain Death / Q000503:physiopathology*; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D009466:Neuromuscular Blocking Agents / Q000008:administration & dosage*; D014019:Tissue Donors
chemical_list: D000777:Anesthetics; D009466:Neuromuscular Blocking Agents
vernacular_title: Anaestesiologiske aspekter ved multiorgandonation.