title: Transdermal scopolamine as treatment of bradyarrhythmias.
abstract: Fifteen patients with different degrees of chronic bradyarrhythmias of supraventricular origin were studied with Holter monitoring before and during application of a transdermal patch of scopolamine. No changes were found in the mean or minimal heart rates, standard deviation of the RR interval, or the degree of bradyarrhythmia. It is concluded that transdermal scopolamine is not an adequate treatment of chronic symptomatic bradyarrhythmias.
authors.affiliation: Servicio de Cardiología, Hospital de la Arrixaca, Murcia, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Salas Nieto
authors.forename: J A
authors.initials: JA
authors.lastname: Ruiperez Abizanda
authors.forename: F
authors.initials: F
authors.lastname: Pico Aracil
authors.forename: G
authors.initials: G
authors.lastname: de la Morena Valenzuela
authors.forename: J A
authors.initials: JA
authors.lastname: Ruiz Ros
mesh_terms: D000279:Administration, Cutaneous; D000293:Adolescent; D000328:Adult; D000368:Aged; D001919:Bradycardia / Q000188:drug therapy* / Q000503:physiopathology; D004341:Drug Evaluation; D015716:Electrocardiography, Ambulatory; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D012601:Scopolamine / Q000008:administration & dosage*; D013997:Time Factors
chemical_list: D012601:Scopolamine