[Electromyographic, histoenzymologic and immunocytochemical aspects of affected muscles in HIV infection. Observations of five cases].
In 5 acquired-immunodeficiency syndrome (AIDS) cases without peripheral neuropathy, we observed myogen clinical signs (diffuse amyotrophy of lower limbs or cramps) or an isolated increase in seric enzyme (LDH, CK). EMG abnormalities were observed in all cases: spontaneous activities (fibrillations and positive sharp waves) in 5 cases, myogenic signs in 2 case. Muscular biopsies were normal in 3 cases and showed myopathic changes in 1 case and polymyositis in another case. Antidystrophin and antilaminin antibodies reactions were altered in 1 case. The spontaneous activities together with these modifications could be in favour of a lesion at the membrane level.
Georgesco
M
M
Laboratoire d'électromyographie, hôpital Gui-de-Chauliac, France.
Reynes
J
J
Pons
F
F
Janbon
F
F
Cadilhac
J
J
D000163:Acquired Immunodeficiency Syndrome / Q000201:enzymology / Q000473:pathology* / Q000503:physiopathology; D000328:Adult; D004576:Electromyography; D004798:Enzymes / Q000097:blood; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009132:Muscles / Q000201:enzymology / Q000473:pathology* / Q000503:physiopathology
D004798:Enzymes
Aspects électromyographiques, histoenzymologiques et immunocytochimiques dans les atteintes musculaires au cours de l'infection par le VIH. A propos de cinq observations.