Percutaneous transfemoral arterial infusion chemotherapy for metastatic liver tumors--placement of 3 Fr balloon catheters.
A 3 Fr single lumen balloon catheter was successfully introduced for arterial infusion chemotherapy by percutaneous transfemoral arterial insertion. This balloon catheter was combined with a 6.3 Fr outer catheter coaxially. After placing the catheter into the target artery, the balloon was ruptured by injecting 1 ml of contrast medium. Alternatively, the balloon was made into a leaky balloon catheter by a small needle puncture before use. In 34 patients with liver tumors, we used this method combined with the continuous infusion of 5-fluorouracil for three to five weeks and once-a-week intra-arterial administration of mitomycin C and adriamycin. The result of this therapy was as follows: CR, 8.8%; PR, 29.4%; NC, 50.0%; and PD, 11.8%. No serious complications were encountered in our series except for some minor arterial problems caused by the catheter tip.
Sawada
S
S
Department of Radiology, Tottori University School of Medicine, Japan.
Fujiwara
Y
Y
Koyama
T
T
Katsube
Y
Y
Kato
T
T
Oshima
T
T
Nakamura
H
H
D000293:Adolescent; D000328:Adult; D000368:Aged; D000792:Angiography / Q000295:instrumentation / Q000379:methods; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D002404:Catheterization / Q000009:adverse effects / Q000295:instrumentation*; D002408:Catheters, Indwelling; D003287:Contrast Media; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D005263:Femoral Artery; D005472:Fluorouracil / Q000008:administration & dosage; D006499:Hepatic Artery; D006801:Humans; D007260:Infusion Pumps; D007261:Infusions, Intra-Arterial / Q000009:adverse effects / Q000295:instrumentation; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D012074:Remission Induction
D003287:Contrast Media; D016685:Mitomycin; D004317:Doxorubicin; D005472:Fluorouracil