title: Hereditary peromelia in Mohair goats.
abstract: The occurrence of a new congenital defect of the appendicular skeleton in Mohair goats is described. The malformation is peromelia and occurs in a familiar pattern. The defect seems to have an autosomal recessive mode of inheritance with variation in the expressivity of the genotype. The pathological abnormalities were described in 8 cases, all characterized by agenesia of the phalanges and parts of the metacarpus or metatarsus affecting one or more limbs. In some cases additional skeletal defects were found. Furthermore, 5 cases were reported by the owners with a description of the limb affected and 1 case was examined clinically. Predisposition for pelvic limbs to be affected was observed. The defect, which does not seem to have been described in goats previously, is phenotypically similar to and possibly also genetically homologous to a defect described in sheep.
authors.affiliation: Department of Pathology and Epidemiology, National Veterinary Laboratory, Copenhapen, Denmark.
authors.forename: J S
authors.initials: JS
authors.lastname: Nielsen
authors.forename: J
authors.initials: J
authors.lastname: Arnbjerg
mesh_terms: D000818:Animals; D001947:Breeding; D000013:Congenital Abnormalities / Q000235:genetics / Q000662:veterinary; D005260:Female; D015511:Goat Diseases / Q000235:genetics*; D006041:Goats; D017880:Limb Deformities, Congenital; D008297:Male; D010375:Pedigree