[Influence of ethanol on the background activity of neurons in the lateral vestibular nucleus of the cat].
Single intravenous administration of ethanol (1 g/kg) to experimental cats influences 95% of investigated neurons of the lateral vestibular nucleus. In most (56.5%) neurons possessing primarily high-frequency background activity of the uninterrupted arrhythmic type ethanol administration has caused a decrease in the impulsation frequency by 84-93%; 14.5% neurons of the burst-group activity demonstrate a primary distinct increase of the average frequency of discharges, prolongation of bursts and the numbers of impulses in them changed 20-30 min after ethanol administration by sharp inhibition of the background activity up to its complete ceasing. A distinct exciting effect has arisen due to the ethanol effect during the whole period of observation in 23.6% of neurons mostly with primary low frequency of the background activity. The rehabilitation of the activity up to the primary level as a rule did not appear even 90 min later. Repeated administration of ethanol in the same dose has induced a cumulative effect.
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D000818:Animals; D002415:Cats; D000431:Ethanol / Q000494:pharmacology*; D008297:Male; D008564:Membrane Potentials / Q000187:drug effects; D009474:Neurons / Q000187:drug effects*; D014726:Vestibular Nuclei / Q000166:cytology / Q000187:drug effects*
D000431:Ethanol
Vliianie étanola na fonovuiu aktivnost' neĭronov lateral'nogo vestibuliarnogo iadra koshki.