title: Propionibacterium acnes endophthalmitis after intracapsular cataract extraction.
abstract: The authors report a case of Propionibacterium acnes endophthalmitis after intracapsular cataract extraction with implantation of an anterior chamber intraocular lens. The patient's chronic inflammation persisted for 5 years after cataract surgery despite treatment with pars plana vitrectomy, intraocular lens removal, topical and oral steroids, and topical fortified antibiotics. Fluctuations in the inflammation were paralleled by changes in the size and appearance of a white plaque on the posterior corneal surface. Anterior chamber tap cultures were positive for P. acnes after 8 days of incubation under anaerobic conditions. The inflammation was not controlled until the posterior corneal plaque, which was the presumed nidus of the chronic infection, was removed and the patient was treated with intravitreal and oral antibiotics.
authors.affiliation: Cornea Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107.
authors.forename: A M
authors.initials: AM
authors.lastname: Chien
authors.forename: I M
authors.initials: IM
authors.lastname: Raber
authors.forename: D H
authors.initials: DH
authors.lastname: Fischer
authors.forename: R C
authors.initials: RC
authors.lastname: Eagle
authors.forename: M A
authors.initials: MA
authors.lastname: Naidoff
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents; D002387:Cataract Extraction / Q000009:adverse effects*; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D009877:Endophthalmitis / Q000188:drug therapy / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D007910:Lenses, Intraocular / Q000009:adverse effects; D011183:Postoperative Complications / Q000382:microbiology*; D011425:Propionibacterium acnes / Q000302:isolation & purification; D014821:Vitrectomy
chemical_list: D000900:Anti-Bacterial Agents