title: [Infiltrating bladder carcinoma with metastatic lymph node involvement: radical treatment and survival].
abstract: Presentation of the results obtained from the study of 64 patients with T2-4 stage vesical carcinoma, treated with radical cystectomy, local lymphadenectomy, with and without complementary radiotherapy, with and without neoadjuvant chemotherapy. The univariate study of 19/64 patients with microscopic nodular disease revealed a significant relationship with the pathological stage but not with the clinical stage. The multivariate study demonstrated that the most relevant prognostic factors are a decrease in tumoral stage (P) and the presence of vascular and/or lymphatic involvement in the TUR-biopsy. The analysis of survival confirms the poor prognosis of patients with metastatic nodular involvement, in spite of the association of pelvic radiotherapy or neoadjuvant chemotherapy to the treatment.
authors.affiliation: Departamento de Urología, Facultad de Medicina, Universidad de Navarra, Pamplona.
authors.forename: F
authors.initials: F
authors.lastname: de Castro Barbosa
authors.forename: P
authors.initials: P
authors.lastname: Sánchez de la Muela
authors.forename: D
authors.initials: D
authors.lastname: Rosell Costa
authors.forename: L
authors.initials: L
authors.lastname: Aguera Fernández
authors.forename: W
authors.initials: W
authors.lastname: Isa Kroon
authors.forename: J E
authors.initials: JE
authors.lastname: Robles García
authors.forename: J J
authors.initials: JJ
authors.lastname: Zudaire Bergera
authors.forename: J M
authors.initials: JM
authors.lastname: Berián Polo
mesh_terms: D000206:Actuarial Analysis; D002295:Carcinoma, Transitional Cell / Q000401:mortality / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D015996:Survival Rate; D001749:Urinary Bladder Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery* / Q000628:therapy
vernacular_title: Carcinoma vesical infiltrante con afectación ganglionar metastásica: tratamiento radical y supervivencia.