Biophysical aspects of neutron scattering from vibrational modes of proteins.
This review describes a major portion of the published work on neutron scattering experiments aimed at measuring large scale motions in proteins. The importance of these motions for enzyme function and oxygen transport is indicated. The theory applicable to each type of neuron scattering measurement is given and results are discussed with a view to biological relevance. New experiments are suggested and a comparison of neutron scattering data is made with results from other techniques such as raman scattering, infrared absorption, photolysis and molecular dynamics simulations.
Martel
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Chalk River Laboratories, AECL Research, Chalk River, Ontario, Canada.
D000818:Animals; D006801:Humans; D009502:Neutrons; D011506:Proteins / Q000737:chemistry*; D012542:Scattering, Radiation; D013329:Structure-Activity Relationship; D014732:Vibration
D011506:Proteins