title: Association of chronic interstitial cystitis, protein-losing enteropathy and paralytic ileus with seronegative systemic lupus erythematosus: case report and review of the literature.
abstract: We report the case of a female patient with seronegative lupus and predominant bladder and intestinal involvement in the form of interstitial cystitis and protein-losing enteropathy. This association is exceptional in the literature but may be underestimated because of frequent latency of interstitial cystitis. It may define a peculiar subgroup of lupus patients usually responsive to steroid therapy. In this case, only cyclophosphamide markedly improved the protein-losing enteropathy but did not influence the bladder disease.
authors.affiliation: Département de Néphrologie, Hôpital Tenon, Paris, France.
authors.forename: Q
authors.initials: Q
authors.lastname: Meulders
authors.forename: C
authors.initials: C
authors.lastname: Michel
authors.forename: P
authors.initials: P
authors.lastname: Marteau
authors.forename: J D
authors.initials: JD
authors.lastname: Grange
authors.forename: B
authors.initials: B
authors.lastname: Mougenot
authors.forename: P
authors.initials: P
authors.lastname: Ronco
authors.forename: F
authors.initials: F
authors.lastname: Mignon
mesh_terms: D000328:Adult; D003520:Cyclophosphamide / Q000627:therapeutic use; D003556:Cystitis / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000188:drug therapy / Q000209:etiology*; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy; D008775:Methylprednisolone / Q000627:therapeutic use; D011504:Protein-Losing Enteropathies / Q000188:drug therapy / Q000209:etiology*
chemical_list: D003520:Cyclophosphamide; D008775:Methylprednisolone