title: Multisystemic eosinophilic epitheliotropic disease in a horse: attempted treatment with hydroxyurea and dexamethasone.
abstract: Equine multisystemic eosinophilic epitheliotropic disease is rare in horses. The clinical signs vary according to the organs affected, the skin and gastrointestinal tract being most commonly involved. This paper gives the first reported description of a horse with multisystemic eosinophilic epitheliotropic disease in the United Kingdom and the attempts to treat it. The horse showed dermatological, gastrointestinal, hepatic, pulmonary and pancreatic involvement. Some improvement was seen when the horse was treated with corticosteroid and hydroxyurea.
authors.affiliation: Department of Veterinary Medicine, University of Bristol School of Veterinary Science, Langford.
authors.forename: M H
authors.initials: MH
authors.lastname: Hillyer
authors.forename: T S
authors.initials: TS
authors.lastname: Mair
mesh_terms: D000818:Animals; D003907:Dexamethasone / Q000627:therapeutic use*; D004802:Eosinophilia / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D004848:Epithelium / Q000473:pathology; D005260:Female; D005767:Gastrointestinal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary; D006734:Horse Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology; D006736:Horses; D006918:Hydroxyurea / Q000627:therapeutic use*; D008107:Liver Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary; D008171:Lung Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary; D010182:Pancreatic Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary; D012871:Skin Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary; D013577:Syndrome
chemical_list: D003907:Dexamethasone; D006918:Hydroxyurea