title: [Heroin abuse and methadone substitution in pregnancy].
abstract: The pre- and postnatal data of 20 pregnant heroin addicts and their neonates are described. 16 women were treated with methadone to prevent withdrawal symptoms. A relatively stabile prenatal condition with a decrease of complications was achieved. On the other hand, the neonates suffered from severe withdrawal symptoms including seizures in spite of intensive paediatric care and prophylactic treatment with barbiturates. After a mean follow-up of one to two years a relatively good neurological development of the children was observed.
authors.affiliation: Zentrum der Frauenheilkunde und Geburtshilfe, Abt. für Geburtshilfe.
authors.forename: A
authors.initials: A
authors.lastname: Vering
authors.forename: J
authors.initials: J
authors.lastname: Seeger
authors.forename: S
authors.initials: S
authors.lastname: Becker
authors.forename: E
authors.initials: E
authors.lastname: Halberstadt
authors.forename: H G
authors.initials: HG
authors.lastname: Bender
mesh_terms: D001238:Asphyxia Neonatorum / Q000209:etiology; D015148:Cardiotocography / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology; D015658:HIV Infections / Q000209:etiology; D003932:Heroin / Q000009:adverse effects*; D006556:Heroin Dependence / Q000534:rehabilitation*; D006801:Humans; D007231:Infant, Newborn; D008691:Methadone / Q000009:adverse effects*; D009357:Neonatal Abstinence Syndrome / Q000209:etiology*; D009460:Neurologic Examination; D011247:Pregnancy; D011248:Pregnancy Complications / Q000534:rehabilitation*; D013036:Spasms, Infantile / Q000209:etiology
chemical_list: D003932:Heroin; D008691:Methadone
vernacular_title: Heroinabusus und Methadon-Substitution in der Schwangerschaft.