Giant basal prolactinoma extending into the nasal cavity.
An unusual case of a giant prolactinoma extending to the nasopharynx and nasal cavity is presented. A 35-year-old man admitted for nasal obstruction and visual disturbances was found to have bilateral anosmia, right homonymous hemianopsia, and a right hemiparesis. The serum prolactin level was 13,300 ng/mL. Radiological examination revealed a large mass invading the skull base and extending into the suprasellar region and the left frontal lobe superiorly and into the nasopharynx inferiorly. Subtotal removal was done through a bilateral orbitofrontal craniotomy, which was followed by radiotherapy and bromocriptine administration. Immunohistochemical analysis confirmed a prolactinoma. The rarity of such a tumor, its location and extension, and the usefulness of magnetic resonance imaging and immunohistochemistry are stressed. Pertinent literature is reviewed.
Iwai
Y
Y
Department of Neurosurgery, Osaka City University Medical School, Japan.
Hakuba
A
A
Khosla
V K
VK
Nishikawa
M
M
Katsuyama
J
J
Inoue
Y
Y
Nishimura
S
S
D000328:Adult; D006801:Humans; D008297:Male; D009296:Nasal Cavity / Q000000981:diagnostic imaging / Q000473:pathology*; D010911:Pituitary Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D015175:Prolactinoma / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography