title: Nucleolar silver staining patterns of lymphocytes in sarcoidosis.
abstract: Bronchoalveolar lavage lymphocytes from 15 patients with pulmonary sarcoidosis and 8 healthy controls were investigated for nucleolar silver staining patterns and lymphocyte subpopulations. Patients with sarcoidosis had increased numbers of silver stained dots versus controls (2.20 +/- 0.24 versus 1.78 +/- 0.07; p less than 0.001). The number of silver stained dots showed the strongest positive correlation to helper cells (OKT 4+) (r = 0.781; p less than 0.0001). These results may be interpreted as further evidence of lymphocytic activation, especially of helper cells (OKT 4+) in pulmonary sarcoidosis.
authors.affiliation: Lungenabteilung, KH der Stadt Wien-Lainz, Vienna, Austria.
authors.forename: W
authors.initials: W
authors.lastname: Popp
authors.forename: H
authors.initials: H
authors.lastname: Zwick
authors.forename: T
authors.initials: T
authors.lastname: Wanke
authors.forename: O
authors.initials: O
authors.lastname: Braun
authors.forename: J H
authors.initials: JH
authors.lastname: Holzner
authors.forename: F
authors.initials: F
authors.lastname: Wachtler
mesh_terms: D000328:Adult; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology*; D002466:Cell Nucleolus / Q000737:chemistry*; D005260:Female; D006801:Humans; D016131:Lymphocyte Subsets / Q000737:chemistry* / Q000648:ultrastructure; D008297:Male; D008875:Middle Aged; D009687:Nuclear Proteins / Q000032:analysis*; D009697:Nucleolus Organizer Region / Q000737:chemistry; D012016:Reference Values; D012507:Sarcoidosis / Q000473:pathology*; D016622:Silver Staining
chemical_list: D009687:Nuclear Proteins