title: [Chromosomal translocation (2;13) in disseminated rhabdomyosarcoma].
abstract: A 12-year-old male with a disseminated alveolar rhabdomyosarcoma is reported. The diagnosis was difficult because of the clinical manifestations and the histological patterns of the bone marrow and a chest wall tumor. Diagnosis was confirmed through the histologic picture of a gum biopsy and the karyotype of the tumoral cells of the bone marrow. Chromosome study revealed a hypotetraploid cell line with the translocation (2;13) characteristic of this type of neoplasias. The usefulness of chromosome studies in solid tumors of childhood is emphasized.
authors.affiliation: Departamento de Investigación en Genética Humana, Instituto Nacional de Pediatría, México, D.F.
authors.forename: P
authors.initials: P
authors.lastname: Pérez-Vera
authors.forename: G
authors.initials: G
authors.lastname: Braun
authors.forename: R
authors.initials: R
authors.lastname: Rivera-Luna
authors.forename: R
authors.initials: R
authors.lastname: Cárdenas
authors.forename: A
authors.initials: A
authors.lastname: Carnevale
mesh_terms: D001706:Biopsy; D001842:Bone and Bones / Q000473:pathology; D002648:Child; D002882:Chromosomes, Human, Pair 13; D002889:Chromosomes, Human, Pair 2; D005881:Gingiva / Q000473:pathology; D006801:Humans; D007621:Karyotyping; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008339:Mandibular Neoplasms / Q000235:genetics* / Q000473:pathology; D012208:Rhabdomyosarcoma / Q000235:genetics* / Q000473:pathology; D013899:Thoracic Neoplasms / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic / Q000235:genetics*
vernacular_title: Translocación cromosómica (2;13) en un rabdomiosarcoma diseminado.