title: Cocaine toxicity in an infant following intranasal instillation of a four percent cocaine solution.
abstract: An 11-week-old infant experienced toxicity following the intranasal instillation of a four percent cocaine solution in preparation for an examination to rule out choanal stenosis. The child recovered fully but required the use of anticonvulsants and admission to the hospital. To our knowledge, this is the first case report where cocaine toxicity was experienced following this routine practice. We present our case and a review of the literature involving other instances where there have been complications with the use of topical cocaine. This report should alert the medical community to the potential complications of using topical cocaine for its anesthetic properties.
authors.affiliation: Department of Ambulatory and Community Pediatrics, Children's Hospital Medical Center, Cincinnati, Ohio 45229.
authors.forename: C J
authors.initials: CJ
authors.lastname: Schubert
authors.forename: S
authors.initials: S
authors.lastname: Wason
mesh_terms: D000281:Administration, Intranasal; D000772:Anesthesia, Local; D002754:Choanal Atresia / Q000175:diagnosis; D003042:Cocaine / Q000009:adverse effects*; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007223:Infant; D012640:Seizures / Q000139:chemically induced; D012996:Solutions
chemical_list: D012996:Solutions; D003042:Cocaine