title: Smoking and risk of leukemia.
abstract: The relation between tobacco use and leukemia was evaluated in a population-based case-control study of 578 white men with leukemia and 820 controls conducted in Iowa and Minnesota during 1981-1984. Risks were significantly elevated for all leukemia (odds ratio (OR) = 1.4) and chronic lymphocytic leukemia (OR = 1.6) for both tobacco users and cigarette smokers. There were significantly elevated risks for cigarette smokers of longest duration for all leukemia (OR = 1.6), chronic myelogenous leukemia (OR = 3.3), and chronic lymphocytic leukemia (OR = 1.6). Thus, the findings of this study provide additional support for an association between smoking and the risk of several types of leukemia.
authors.affiliation: Epidemiology and Biostatistics Program, National Cancer Institute, Bethesda, MD 20892.
authors.forename: L M
authors.initials: LM
authors.lastname: Brown
authors.forename: R
authors.initials: R
authors.lastname: Gibson
authors.forename: A
authors.initials: A
authors.lastname: Blair
authors.forename: L F
authors.initials: LF
authors.lastname: Burmeister
authors.forename: L M
authors.initials: LM
authors.lastname: Schuman
authors.forename: K P
authors.initials: KP
authors.lastname: Cantor
authors.forename: J F
authors.initials: JF
authors.lastname: Fraumeni
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D006801:Humans; D007938:Leukemia / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D010947:Plants, Toxic; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects*; D014030:Tobacco, Smokeless / Q000009:adverse effects