Steatohepatitis and fatal hepatic failure after biliopancreatic diversion.
Steatohepatitis and hepatic failure are well known complications of jejunoileal bypass, an operation that has been abandoned as a treatment for severe obesity because of its potential for adverse metabolic consequences. Biliopancreatic diversion is a novel operation designed to avoid the harmful effects of jejunoileal bypass. Although it has not gained wide acceptance, this procedure is being advocated by some surgeons as a safe and effective treatment for severe obesity. Published reports indicate that liver histology generally remains stable or improves after biliopancreatic diversion. We present a patient who developed steatohepatitis and subsequently died in hepatic failure after this operation. Severe liver disease should be added to the list of complications that may follow biliopancreatic diversion.
Grimm
I S
IS
Department of Internal Medicine (Gastroenterology Division), Naval Hospital, San Diego, California.
Schindler
W
W
Haluszka
O
O
D000328:Adult; D015904:Biliopancreatic Diversion / Q000009:adverse effects*; D005234:Fatty Liver / Q000209:etiology*; D005260:Female; D006505:Hepatitis / Q000209:etiology; D006801:Humans; D009765:Obesity / Q000601:surgery*