The influence of different types of breakfast on the absorption of paracetamol among members of an ethnic group.
It is well known that food influences the absorption and therapeutic efficacy of many drugs. In this study, the influence of three different types of breakfast, on the absorption of paracetamol was studied in a South African ethnic population group (Tswanas). The results indicated that breakfasts with a high fat content delayed the absorption of paracetamol to the largest extent while breakfasts with a high carbohydrate content delayed the absorption of paracetamol to a lesser extent.
Wessels
J C
JC
Department of Pharmaceutics, Potchefstroom University of Christian Higher Education, South Africa.
Koeleman
H A
HA
Boneschans
B
B
Steyn
H S
HS
D000082:Acetaminophen / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D000293:Adolescent; D000328:Adult; D000818:Animals; D001682:Biological Availability; D004531:Eggs; D005006:Ethnicity; D005215:Fasting / Q000097:blood; D005260:Female; D005502:Food / Q000145:classification; D006801:Humans; D007408:Intestinal Absorption; D008460:Meat; D013019:South Africa; D013552:Swine; D013607:Tablets; D003313:Zea mays
D013607:Tablets; D000082:Acetaminophen