[Optimization of the conditions for extracting metronidazole with organic solvents].
Optimal conditions of metronidazole extraction from aqueous solutions by different solvents using a mathematical method of experiment planning (latin square) were studied. It was stated that optimal conditions of metronidazole extraction from aqueous solutions were: extraction time (5 min.), pH medium-6, extractant-isoamyl spirit in saturation of aqueous phase with ammonium sulfate.
Belikov
V G
VG
Vergeĭchik
T Kh
TKh
Tsybulina
M G
MG
D006801:Humans; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents; D008722:Methods; D008795:Metronidazole / Q000302:isolation & purification* / Q000506:poisoning; D012997:Solvents; D013997:Time Factors
D007202:Indicators and Reagents; D012997:Solvents; D008795:Metronidazole
Optimizatsiia usloviĭ izvlecheniia metronidazola organicheskimi rastvoriteliami.