title: [Comparison of two methods for conscious sedation in maxillofacial surgery with local anesthesia].
abstract: A randomised, prospective study was conducted to compare the efficiency and safety of methods for intravenous conscious sedation in patients undergoing oral surgery under local analgesia. 150 systemically healthy patients (ASA Class I and II) participated. Three groups were formed: group 1 received 0.05 mg/kg midazolam; group 2 0.05 mg/kg midazolam, 1.5 mg/kg tramadol, 50 mg alizaprid; group 3 0.05 mg/kg midazolam, 0.2 mg/kg nalbuphine, 50 mg alizaprid. Blood pressure, heart rate and oxygen saturation were measured throughout the procedure. The results confirmed that the use of nalbuphine (group 3) allows a reduction in the mean dosage of midazolam required to produce satisfactory sedation and effected a more rapid recovery time compared to group 12 and 2. With the combination nalbuphine and alizaprid nausea and vomiting could be reduced for the most part compared to group 2.
authors.affiliation: Klinik und Poliklinik für Mund-Kiefer-Gesichtschirurgie Heidelberg.
authors.forename: J
authors.initials: J
authors.lastname: Zöller
authors.forename: B
authors.initials: B
authors.lastname: Zöller
authors.forename: S
authors.initials: S
authors.lastname: Hassfeld
authors.forename: J
authors.initials: J
authors.lastname: Köhler
mesh_terms: D016292:Procedural Sedation / Q000379:methods*; D006801:Humans; D008874:Midazolam; D009266:Nalbuphine; D011446:Prospective Studies; D011759:Pyrrolidines; D011897:Random Allocation; D014147:Tramadol
chemical_list: D011759:Pyrrolidines; D014147:Tramadol; D009266:Nalbuphine; C033968:alizapride; D008874:Midazolam
vernacular_title: Vergleich zweier Analgosedierungs-verfahren bei kieferchirurgischen Eingriffen in Lokalanästhesie.