Eye movements in myotonic dystrophy.
Smooth pursuit eye movements were studied with infrared reflection equipment in 10 patients with myotonic dystrophy and in 10 age- and sex-matched controls. Smooth pursuit gain, measured after correction for catch-up saccades, was decreased in the patient group. Normal latencies of saccadic eye movements made a lack of attention an unlikely explanation for this low gain. Likewise, presence of catch-up saccades and normal fixation made it unlikely that extra-ocular myopathy explained the low smooth pursuit gain. We suggest that periventricular white matter abnormalities represent a more likely explanation.
Bollen
E
E
Department of Neurology, University Hospital Leiden, The Netherlands.
den Heyer
J C
JC
Tolsma
M H
MH
Bellari
S
S
Bos
J E
JE
Wintzen
A R
AR
D000328:Adult; D000368:Aged; D005133:Eye Movements; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009223:Myotonic Dystrophy / Q000503:physiopathology*; D011698:Pursuit, Smooth; D012438:Saccades