title: Treatment of symptomatic cholelithiasis in France. A decision analysis comparing cholecystectomy and biliary lithotripsy.
abstract: To determine the potential role of extracorporeal shock wave lithotripsy (ESWL) in the treatment of symptomatic gallstone patients in France, a simulation model evaluated the health and economic effects of three different treatment strategies. Decision analysis of conventional cholecystectomy alone and either of two strategies using a combination of biliary lithotripsy and conventional cholecystectomy reveals that a strategy employing biliary ESWL results in a significant number of successfully treated patients, thus avoiding the risks and costs of abdominal surgery. Moreover, cost analysis shows that expanding the use of lithotripsy to all patients for whom the procedure is indicated increases the average cost per successfully treated patient, but, more importantly, decreases the overall costs incurred by the cohort. From a societal viewpoint, a policy using biliary ESWL in appropriate patients is superior to one of cholecystectomy alone, from both clinical and economic perspectives.
authors.affiliation: Ecole Polytechnique and Assistance, Publique-Hôpitaux de Paris.
authors.forename: A M
authors.initials: AM
authors.lastname: Fendrick
authors.forename: G
authors.initials: G
authors.lastname: de Pouvourville
authors.forename: C
authors.initials: C
authors.lastname: Bitker
authors.forename: G
authors.initials: G
authors.lastname: Pelletier
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002763:Cholecystectomy / Q000191:economics / Q000379:methods; D002769:Cholelithiasis / Q000191:economics / Q000628:therapy*; D003365:Costs and Cost Analysis; D003661:Decision Support Techniques; D003663:Decision Trees; D005260:Female; D005602:France; D006801:Humans; D008096:Lithotripsy / Q000191:economics; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D012008:Recurrence; D012680:Sensitivity and Specificity; D013673:Technology Assessment, Biomedical / Q000379:methods*