Apomorphine in malignant syndrome due to levodopa withdrawal.
We report a case of neuroleptic malignant syndrome (NMS) following abrupt reduction of chronic levodopa treatment in a 71 year old female parkinsonian patient. The NMS resolved within 24 hours of the addition of apomorphine to levodopa therapy.
Bonuccelli
U
U
Clinica Neurologica, Università di Pisa.
Piccini
P
P
Corsini
G U
GU
Muratorio
A
A
D000368:Aged; D001058:Apomorphine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007980:Levodopa / Q000009:adverse effects* / Q000627:therapeutic use; D009459:Neuroleptic Malignant Syndrome / Q000188:drug therapy*; D010300:Parkinson Disease / Q000150:complications / Q000188:drug therapy; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy*
D007980:Levodopa; D001058:Apomorphine