Recurrence of extrahepatic biliary atresia in two half sibs.
Extrahepatic biliary atresia (EHBA) usually is a sporadic disorder. Familial cases, including occurrence in sibs and twins, have been reported. We report the first recurrence of EHBA in two half sibs born to a common father and unrelated mothers and suggest the possibility of gonadal mosaicism for a new dominant mutation.
Gunasekaran
T S
TS
Division of Pediatric Gastroenterology, British Columbia Children's Hospital, University of British Columbia, Vancouver, Canada.
Hassall
E G
EG
Steinbrecher
U P
UP
Yong
S L
SL
D001656:Biliary Atresia / Q000235:genetics* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010375:Pedigree