title: [The prospective evolution of the efficacy of antiarrhythmia therapy in paroxysmal supraventricular tachycardia in patients with the ventricular pre-excitation syndrome].
abstract: Evolution of the effectiveness of antiarrhythmic drugs used in 240 patients with preexcitation syndrome to arrest episodes of paroxysmal supraventricular tachycardia was analysed prospectively. The first intravenous administration was effective in 97, 93.3, 80.9, 75, 70.3, 60, 48% of cases for novocainamid, verapamil, cordarone, disopyramide, ajmaline, ethacizine, mexitil and inderal, respectively. When observed in prospective evolution for 10-14 years, overall group efficacy dropped from 81.3% at first administration to 21.4%.
authors.forename: I G
authors.initials: IG
authors.lastname: Fomina
authors.forename: V V
authors.initials: VV
authors.lastname: Iankin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011226:Pre-Excitation Syndromes / Q000188:drug therapy* / Q000453:epidemiology; D011446:Prospective Studies; D013614:Tachycardia, Paroxysmal / Q000188:drug therapy* / Q000453:epidemiology; D013617:Tachycardia, Supraventricular / Q000188:drug therapy* / Q000453:epidemiology
chemical_list: D000889:Anti-Arrhythmia Agents
vernacular_title: Prospektivnaia évoliutsiia éffektivnosti antiaritmicheskoĭ terapii pri paroksizmal'noĭ nadzheludochkovoĭ takhikardii u bol'nykh s sindromom prezhdevremennogo vozbuzhdeniia zheludochkov.