Isolated ascending colon ulceration in a patient with chronic renal insufficiency.
Chronic renal hemodialysis or transplantation may be accompanied by a myriad of gastrointestinal problems. Ischemic bowel disease, spontaneous perforation diverticulitis, appendicitis, fistulae, and angiodysplasia have all been reported in the literature. Isolated colonic ulcerations have been described as a cause of both massive hemorrhage and spontaneous perforation. The exact predisposing factors are unknown. Ischemia, immunosuppression, and cytomegalovirus may play important roles in pathogenesis. This article describes a case of both hemorrhage and spontaneous colonic perforation accompanying end-stage renal disease in a patient who was not undergoing long-term dialysis or posttransplantation immunosuppression.
Brown
K M
KM
Washington Hospital Center, Washington, DC.
D000368:Aged; D003108:Colonic Diseases / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D014456:Ulcer / Q000150:complications / Q000175:diagnosis* / Q000601:surgery