title: Haemophilus influenzae in New Zealand: subtyping of isolates from invasive disease using outer membrane protein profiling.
abstract: Invasive Haemophilus influenzae type b disease affects one in every 350 New Zealand children by the age of five, leaving some with severe handicap. As part of a national surveillance programme aimed at determining the epidemiology of H influenzae b disease in this country, the diversity of local isolates causing invasive disease was examined using outer membrane protein (OMP) profiling. Of 81 H influenzae b isolates examined, 70 (86%) had identical OMP profiles. Among the other 11 H influenzae b isolates, eight different OMP profiles were observed. Nontype b Haemophilus influenzae isolates (n = 13) showed a greater diversity of OMP patterns.
authors.affiliation: New Zealand Communicable Disease Centre, Porirua.
authors.forename: G A
authors.initials: GA
authors.lastname: Saravani
authors.forename: D R
authors.initials: DR
authors.lastname: Martin
authors.forename: M T
authors.initials: MT
authors.lastname: Arriesgado
mesh_terms: D001425:Bacterial Outer Membrane Proteins / Q000032:analysis*; D002675:Child, Preschool; D004591:Electrophoresis, Polyacrylamide Gel; D006192:Haemophilus Infections / Q000453:epidemiology / Q000382:microbiology*; D006193:Haemophilus influenzae / Q000145:classification*; D006801:Humans; D007223:Infant; D009520:New Zealand / Q000453:epidemiology; D016036:Seroepidemiologic Studies; D012703:Serotyping
chemical_list: D001425:Bacterial Outer Membrane Proteins