A radioautographic study of [3H]-A 23187 (calcimycin) in components of the brain. Distribution in different cell types of the diencephalo-mesencephalic roof.
The distribution of the ionophore [3H]-A 23187 was examined by means of light and electron microscopy in elements of the central nervous system located in the diencephalo-mesencephalic roof. A 23187 is not evenly distributed in the components studied (ependyma, secretory ependyma of the subcommissural organ and neurons of the mesencephalon). At the cellular level, A 23187 appears preferentially associated with the cytoplasmic membrane as well as with the internal membranous system.
Meiniel
R
R
Didier
R
R
Meiniel
A
A
Jeminet
G
G
Prudhomme
M
M
D000818:Animals; D001345:Autoradiography; D000001:Calcimycin / Q000737:chemistry / Q000493:pharmacokinetics*; D002645:Chickens; D004027:Diencephalon / Q000378:metabolism* / Q000648:ultrastructure; D008636:Mesencephalon / Q000378:metabolism* / Q000648:ultrastructure; D015394:Molecular Structure; D014018:Tissue Distribution
D000001:Calcimycin