[Role of oncogenes and anti-oncogenes in dermatology].
Cell growth is controlled by two types of genes, i.e., activating genes (oncogenes) and negative regulator genes (antioncogenes). Studies have shown that malignant transformation of a cell can result from either increased oncogene activity or decreased antioncogene activity. Current knowledge of genes relevant to dermatology is discussed.
Basset-Séguin
N
N
Laboratoire de Dermatologie Moléculaire, CNRS/CRBM, Montpellier, France.
Guillot
B
B
Dereure
O
O
Moles
J P
JP
Guilhou
J J
JJ
D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000235:genetics; D004815:Epidermal Growth Factor / Q000235:genetics; D016147:Genes, Tumor Suppressor / Q000235:genetics*; D016158:Genes, p53 / Q000235:genetics; D006801:Humans; D051379:Mice; D011519:Proto-Oncogenes / Q000235:genetics*; D011565:Psoriasis / Q000235:genetics; D012878:Skin Neoplasms / Q000235:genetics*
D004815:Epidermal Growth Factor
Place des oncogènes et des anti-oncogènes en dermatologie.