title: Induction of labour with prostaglandin gel in patients with unfavourable cervices.
abstract: 151 primigravid patients with Bishop scores of 4 or less were induced with prostaglandin E2 gel using an initial dose of 2 mg followed by 1 mg or 2 mg at 6 hours. Eighty one patients (53.6 per cent) were in established labour or had delivered by 12 hours, and a further 31 (20.5 per cent) had achieved successful ripening of the cervix. Ninety per cent and 64.5 per cent respectively achieved vaginal delivery and although 39 patients failed to respond to this regime, 72 per cent delivered vaginally after augmentation. No case of hypertonus was recorded and only one patient had abdominal delivery for "failed induction". This regime provides an effective means of induction of labour for a difficult group of patients with little worry of overstimulation and low "failed induction" rates.
authors.affiliation: North Tees General Hospital, Cleveland.
authors.forename: S M
authors.initials: SM
authors.lastname: Walton
authors.forename: M J
authors.initials: MJ
authors.lastname: Maresh
authors.forename: A
authors.initials: A
authors.lastname: Murray
authors.forename: M D
authors.initials: MD
authors.lastname: Read
authors.forename: J J
authors.initials: JJ
authors.lastname: Walker
mesh_terms: D000282:Administration, Intravaginal; D000328:Adult; D002585:Cesarean Section; D015232:Dinoprostone / Q000008:administration & dosage*; D005260:Female; D005782:Gels; D006801:Humans; D007751:Labor, Induced / Q000379:methods*; D011247:Pregnancy
chemical_list: D005782:Gels; D015232:Dinoprostone