title: Eye movements in myotonic dystrophy.
abstract: Smooth pursuit eye movements were studied with infrared reflection equipment in 10 patients with myotonic dystrophy and in 10 age- and sex-matched controls. Smooth pursuit gain, measured after correction for catch-up saccades, was decreased in the patient group. Normal latencies of saccadic eye movements made a lack of attention an unlikely explanation for this low gain. Likewise, presence of catch-up saccades and normal fixation made it unlikely that extra-ocular myopathy explained the low smooth pursuit gain. We suggest that periventricular white matter abnormalities represent a more likely explanation.
authors.affiliation: Department of Neurology, University Hospital Leiden, The Netherlands.
authors.forename: E
authors.initials: E
authors.lastname: Bollen
authors.forename: J C
authors.initials: JC
authors.lastname: den Heyer
authors.forename: M H
authors.initials: MH
authors.lastname: Tolsma
authors.forename: S
authors.initials: S
authors.lastname: Bellari
authors.forename: J E
authors.initials: JE
authors.lastname: Bos
authors.forename: A R
authors.initials: AR
authors.lastname: Wintzen
mesh_terms: D000328:Adult; D000368:Aged; D005133:Eye Movements; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009223:Myotonic Dystrophy / Q000503:physiopathology*; D011698:Pursuit, Smooth; D012438:Saccades