title: Precautions when using antiprostaglandins.
abstract: Antiprostaglandins are effective for relief of pain of low to moderate intensity. The majority of these agents interfere with clotting function, and they should not be used on animals with potential coagulopathies. With high dosage or long-term treatment, gastrointestinal irritation and ulceration are probable. NSAIDs should not be used in conjunction with methoxyflurane because of the potential for renal damage. Care should be taken to avoid hypotension with any anesthetic to obviate renal complications.
authors.affiliation: Department of Veterinary Anesthesiology, Radiology, and Surgery, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada.
authors.forename: P H
authors.initials: PH
authors.lastname: Cribb
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D002371:Cat Diseases / Q000139:chemically induced*; D002415:Cats; D000075202:Contraindications; D004283:Dog Diseases / Q000139:chemically induced*; D004285:Dogs; D011448:Prostaglandin Antagonists / Q000009:adverse effects*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D011448:Prostaglandin Antagonists