title: Nonbronchoscopic approach to bronchoalveolar lavage in children with artificial airways.
abstract: Bronchoalveolar lavage (BAL) performed with a fiberoptic bronchoscope (FOB) is a useful method for sampling alveolar contents. Since the smallest FOB with a channel has a diameter of 3.6 mm, BAL is difficult to accomplish through artificial airways (AA) less than 5.0 mm I.D. We used a 4F balloon wedge pressure catheter to perform BAL through small AA. Supplemental O2 or ventilatory support was delivered via an adaptor through which the catheter was introduced. After it was passed distal to the AA, the balloon was inflated with normal saline (NS) to a predetermined volume, and advanced until resistance was felt. The balloon was deflated, advanced slightly, and then reinflated to achieve airway occlusion. Five aliquots of 0.75 mL/kg of NS were used for BAL. The procedure was performed in 20 children from 1 month (950 g) to 6 1/2 years of age (median, 9 months). All specimens contained abundant alveolar macrophages, indicating good recovery of alveolar contents. Clinically significant information was obtained in 17 (85%) cases, and no patient required an open lung biopsy. In conclusion, nonbronchoscopic bronchoalveolar lavage is a valuable method for obtaining alveolar contents in children with small AA that preclude the use of an FOB, and it obviates the need for open lung biopsy in many patients. This technique could be used as a research tool for measuring constituents of alveolar contents in infants and small animals.
authors.affiliation: St. Christopher's Hospital for Children, Department of Pediatrics, Temple University School of Medicine, Philadelphia, Pennsylvania 19134-1095.
authors.forename: B E
authors.initials: BE
authors.lastname: Alpert
authors.forename: B P
authors.initials: BP
authors.lastname: O'Sullivan
authors.forename: H B
authors.initials: HB
authors.lastname: Panitch
mesh_terms: D002406:Catheterization, Peripheral / Q000295:instrumentation; D002675:Child, Preschool; D004867:Equipment Design; D006801:Humans; D007223:Infant; D007440:Intubation; D012137:Respiratory System; D007507:Therapeutic Irrigation / Q000295:instrumentation* / Q000379:methods*