Esterase activity toward the diastereomers of cefuroxime axetil in the rat and dog.
Mosher
G L
GL
Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, Indiana 46285.
McBee
J
J
Shaw
D B
DB
D000818:Animals; D002444:Cefuroxime / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D002851:Chromatography, High Pressure Liquid; D004285:Dogs; D004386:Duodenum / Q000378:metabolism / Q000648:ultrastructure; D004950:Esterases / Q000378:metabolism*; D005260:Female; D006868:Hydrolysis; D007408:Intestinal Absorption / Q000502:physiology*; D007421:Intestine, Small / Q000378:metabolism / Q000648:ultrastructure; D008297:Male; D008871:Microvilli / Q000378:metabolism; D015394:Molecular Structure; D011355:Prodrugs / Q000493:pharmacokinetics*; D051381:Rats; D011919:Rats, Inbred Strains; D013237:Stereoisomerism
D011355:Prodrugs; D004950:Esterases; D002444:Cefuroxime; C040738:cefuroxime axetil