title: [Biological and clinical prevalence of pollinosis caused by ragweeds of the upper valley of the Rhône corridor].
abstract: An epidemiological study of ragweed allergy was conducted on 646 employees belonging to 6 factories located in the Rhone valley south of the city of Lyon. Information on seasonal evocative clinical symptoms was obtained through a self-administered questionnaire. Biological prevalence was assessed by measuring anti-ragweed IgE specific antibodies. Measurements were performed by immunoenzymatic assay (W1 Phadezym RAST from Pharmacia). 34 (5,4%) subjects had evocative symptoms whereas 37 (5,9%) had increased specific IgE. Persons with the highest IgE levels were symptomatic. Concordance between symptoms and biology was 35% (12/34). Results indicate that sensitization level varies according to the location of the factory and people's residence, the risk to become allergic being of 10% in the most exposed population. This data emphasize the need to promote anti-ragweed eradication policy.
authors.affiliation: Centre hospitalier Lyon Sud Pierre Benite.
authors.forename: R
authors.initials: R
authors.lastname: Harf
authors.forename: J C
authors.initials: JC
authors.lastname: Contassot
authors.forename: C
authors.initials: C
authors.lastname: Dechamp
authors.forename: B
authors.initials: B
authors.lastname: Despres
authors.forename: P
authors.initials: P
authors.lastname: Deviller
authors.forename: P
authors.initials: P
authors.lastname: Diter
authors.forename: Y
authors.initials: Y
authors.lastname: Garcier
authors.forename: R
authors.initials: R
authors.lastname: Liard
authors.forename: F
authors.initials: F
authors.lastname: Neukirch
authors.forename: P
authors.initials: P
authors.lastname: Quelin
mesh_terms: D000328:Adult; D005602:France / Q000453:epidemiology; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007221:Industry; D011058:Pollen / Q000276:immunology; D015995:Prevalence; D011852:Radioallergosorbent Test; D006255:Rhinitis, Allergic, Seasonal / Q000453:epidemiology* / Q000209:etiology / Q000276:immunology / Q000517:prevention & control; D012621:Seasons
chemical_list: D007073:Immunoglobulin E
vernacular_title: Prévalence biologique et clinique de la pollinose due aux ambroisies dans la vallée supérieure du couloir rhodanien.