title: Scaling up the nervous system of Caenorhabditis elegans: is one ape equal to 33 million worms?
abstract: Although vastly different, both the mammalian brain and the nematode Caenorhabditis elegans' nervous system must contribute critically to assure survival. Two quantitative conditions which place bounds on networks for connectedness and stability are tested on the published neural network of C. elegans and fit. Consideration of networks scaled up to mammalian size and confined between these bounds suggests that perhaps, the entire spectrum of brain size may be built between these bounds. Further consequences of increasing brain size relate to the trade-off between complexity, providing internal resistance to individual damage, and redundancy of population, as survival mechanisms.
authors.affiliation: Department of Computer Medicine, George Washington University School of Medicine, Washington, D.C. 20037.
authors.forename: W S
authors.initials: WS
authors.lastname: Yamamoto
authors.forename: T B
authors.initials: TB
authors.lastname: Achacoso
mesh_terms: D000818:Animals; D002107:Caenorhabditis; D015186:Hominidae; D008959:Models, Neurological; D009415:Nerve Net / Q000033:anatomy & histology* / Q000502:physiology; D009420:Nervous System / Q000033:anatomy & histology*; D009424:Nervous System Physiological Phenomena; D009434:Neural Pathways; D009474:Neurons / Q000502:physiology