title: Lentigo maligna. Cytogenetic, ultrastructural, and phenotypic characterization of a primary cell culture.
abstract: Lentigo maligna is an early cutaneous neoplastic lesion. This article presents the cytogenetic, ultrastructural, and phenotypic characterization of a primary cell culture obtained from a patient affected with lentigo maligna. Two cellular clones were identified, both characterized by chromosomal markers involving chromosome 10 with a breakpoint at 10q26.
authors.affiliation: Dipartimento di Medicina Sperimentale, Università degli Studi di Roma La Sapienza, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Grammatico
authors.forename: A
authors.initials: A
authors.lastname: Modesti
authors.forename: K
authors.initials: K
authors.lastname: Steindl
authors.forename: S
authors.initials: S
authors.lastname: Scarpa
authors.forename: A
authors.initials: A
authors.lastname: Heouaine
authors.forename: M
authors.initials: M
authors.lastname: Picardo
authors.forename: G
authors.initials: G
authors.lastname: Del Porto
mesh_terms: D002872:Chromosome Deletion; D002879:Chromosomes, Human, Pair 10; D005455:Fluorescent Antibody Technique; D006801:Humans; D007911:Lentigo / Q000235:genetics* / Q000473:pathology; D008297:Male; D008544:Melanocytes / Q000473:pathology; D008545:Melanoma / Q000235:genetics* / Q000473:pathology; D008854:Microscopy, Electron; D008875:Middle Aged; D012878:Skin Neoplasms / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic / Q000235:genetics*; D014407:Tumor Cells, Cultured; D014746:Vimentin / Q000032:analysis
chemical_list: D014746:Vimentin