title: Significance of urinary cadmium concentration in a Japanese population environmentally exposed to cadmium.
abstract: An epidemiological study was performed on 1,815 cadmium-exposed and 240 nonexposed inhabitants of the Kakehashi River basin in Ishikawa, Japan. The significance of urinary cadmium concentration as an indicator of internal dose in a general environment polluted by cadmium was investigated. The mean urinary cadmium concentration (Cd-U) increased in a dose-related manner when the subjects were classified according to the average cadmium concentration in their village rice and according to their period of residence in the polluted area. As total cadmium intake increased, Cd-U also increased, and strong correlations were found (r = .93 in men and r = .88 in women). Therefore, it was concluded that, on a group basis, Cd-U is a useful indicator of the internal dose of environmental cadmium exposure.
authors.affiliation: Department of Hygiene, Chiba University, School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Kido
authors.forename: K
authors.initials: K
authors.lastname: Nogawa
authors.forename: M
authors.initials: M
authors.lastname: Ohmichi
authors.forename: R
authors.initials: R
authors.lastname: Honda
authors.forename: I
authors.initials: I
authors.lastname: Tsuritani
authors.forename: M
authors.initials: M
authors.lastname: Ishizaki
authors.forename: Y
authors.initials: Y
authors.lastname: Yamada
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002104:Cadmium / Q000737:chemistry / Q000652:urine*; D004034:Diet Surveys; D004781:Environmental Exposure; D004784:Environmental Monitoring / Q000379:methods* / Q000592:standards; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D012275:Oryza / Q000737:chemistry*; D012044:Regression Analysis; D012111:Residence Characteristics; D013997:Time Factors; D014877:Water Pollution, Chemical / Q000009:adverse effects / Q000032:analysis
chemical_list: D002104:Cadmium