title: Clinical course and outcome of substance abuse disorders in adolescents.
abstract: Seven percent (19 of 275) of children and adolescents not ascertained for seeking treatment received a DSM-III diagnosis of alcohol or drug use disorder. Their entire families were recruited into a research program designed to study the risk to offspring of parental psychopathology. The ages of those diagnosed were between 12 and 18 years. The drug and alcohol use disorders had a mean duration of 2 years, and the adolescents who remitted had a high likelihood of developing subsequent psychopathology. These adolescents also showed high rates of other psychiatric disorders. A high rate of alcoholism was found among their parents.
authors.affiliation: Department of Psychiatry and Human Behavior, Brown University Medical School, Butler Hospital, Providence, Rhode Island 02906.
authors.forename: M B
authors.initials: MB
authors.lastname: Keller
authors.forename: P W
authors.initials: PW
authors.lastname: Lavori
authors.forename: W
authors.initials: W
authors.lastname: Beardslee
authors.forename: J
authors.initials: J
authors.lastname: Wunder
authors.forename: D L
authors.initials: DL
authors.lastname: Drs
authors.forename: D
authors.initials: D
authors.lastname: Hasin
mesh_terms: D000293:Adolescent; D000437:Alcoholism / Q000523:psychology / Q000534:rehabilitation*; D002648:Child; D002653:Child Behavior Disorders / Q000523:psychology / Q000534:rehabilitation; D016241:Child of Impaired Parents / Q000523:psychology*; D003866:Depressive Disorder / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010552:Personality Assessment; D011569:Psychiatric Status Rating Scales; D011619:Psychotropic Drugs; D012008:Recurrence; D012307:Risk Factors; D019966:Substance-Related Disorders / Q000523:psychology / Q000534:rehabilitation*
chemical_list: D011619:Psychotropic Drugs