[Postpartum diabetes screening: value of fructosamine determination].
After birth of an infant with a birthweight of 4000 g or more maternal glucose tolerance should be examined. We measured blood glucose values after a 100 g oral glucose challenge and compared them with serum fructosamine values of the same subjects. 40 women who had given birth to an infant with macrosomia (group I) were matched with 40 women who had delivered babies with normal birthweight (group II). Impaired glucose tolerance was found in 6 women (15%) of group I, and in one woman (2.5%) of group II. Fructosamine values were within the normal range in each of the seven women (1.74 + 0.2 mmol/l vs 1.73 + 0.2 mmol/l). Thus, fructosamine determination is not sensitive enough to detect impaired glucose tolerance in asymptomatic women post partum. It is not feasible to replace the oral glucose tolerance test in screening for gestational diabetes mellitus.
Huter
O
O
Universitätsklinik für Frauenheilkunde, Universitätsklinik für Innere Medizin Innsbruck.
Brezinka
C
C
Sölder
E
E
Kölle
D
D
Drexel
H
H
D001724:Birth Weight; D005260:Female; D005320:Fetal Macrosomia / Q000097:blood*; D019270:Fructosamine; D005951:Glucose Tolerance Test; D006595:Hexosamines / Q000097:blood*; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000097:blood* / Q000175:diagnosis; D012016:Reference Values
D006595:Hexosamines; D019270:Fructosamine
Postpartales Diabetes-Screening: Wertigkeit der Fruktosaminbestimmung.