Relation between urinary beta-aminoisobutyric acid excretion and concentration of lead in the blood of workers occupationally exposed to lead.
Urinary beta-aminoisobutyric acid (ABA) concentration was determined by fluorometric high performance liquid chromatography in 22 workers occupationally exposed to lead. The urinary excretion of ABA was increased with increasing exposure to lead. The excretion of urinary ABA had a significant correlation with concentration of lead in blood (Pb-B) (r = 0.581), similar to the correlation of Pb-B with urinary delta-aminolaevulinic acid (ALA) concentration (r = 0.563). The determination of urinary ABA concentration in workers exposed to lead, therefore, may offer a new approach for evaluating the health effect of lead.
Tomokuni
K
K
Department of Community Health Science, Saga Medical School, Japan.
Ichiba
M
M
Mori
K
K
D000328:Adult; D000368:Aged; D000621:Aminoisobutyric Acids / Q000652:urine*; D000622:Aminolevulinic Acid / Q000652:urine; D002851:Chromatography, High Pressure Liquid; D005260:Female; D006801:Humans; D007854:Lead / Q000009:adverse effects / Q000097:blood*; D008297:Male; D008669:Metallurgy; D008875:Middle Aged; D016273:Occupational Exposure
D000621:Aminoisobutyric Acids; D007854:Lead; D000622:Aminolevulinic Acid; C033435:3-aminoisobutyric acid