Retinal pigment epithelium implantation in the rabbit: technique and morphology.
Dysfunction of the retinal pigment epithelium (RPE) is a major component of many degenerative disorders of the retina. We have developed a modified pars plana technique for subretinal implantation of homologous, cultured, carbon-loaded RPE cells in the rabbit. The natural history and morphologic behavior of the implanted RPE cells for up to 6 weeks after transplantation were observed in successful procedures.
el Dirini
A A
AA
Department of Ophthalmology, University of Southern California School of Medicine, Los Angeles.
Wang
H M
HM
Ogden
T E
TE
Ryan
S J
SJ
D000818:Animals; D002244:Carbon; D002478:Cells, Cultured; D010857:Pigment Epithelium of Eye / Q000637:transplantation* / Q000648:ultrastructure; D011817:Rabbits; D012160:Retina / Q000601:surgery* / Q000648:ultrastructure; D014184:Transplantation, Homologous / Q000379:methods
D002244:Carbon