Decreased bacterial adherence to silver-coated stent material: an in vitro study.
Bacteria are important in causing biliary stent blockage through adherence and subsequent biofilm formation. In our in vitro system, surface modification using test polyurethane discs with silver coating led to a reduction in the number of adherent bacteria compared with untreated controls by 10- to 100-fold in an apparently dose-related manner. The effect was more marked in the presence of bile. These results suggest that silver coating may have a potential benefit in preventing stent blockage.
Leung
J W
JW
Department of Medicine, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin.
Lau
G T
GT
Sung
J J
JJ
Costerton
J W
JW
D001422:Bacterial Adhesion; D001646:Bile; D004926:Escherichia coli / Q000502:physiology; D006801:Humans; D066298:In Vitro Techniques; D008855:Microscopy, Electron, Scanning; D011140:Polyurethanes; D012834:Silver; D015607:Stents; D013499:Surface Properties
D011140:Polyurethanes; D012834:Silver