title: Effect of different kinds of dietary casein on blood cholesterol and triglycerides in pair fed rats.
abstract: After casein intake, serum cholesterol levels are dependent on many experimental conditions in rats. The effect of the method of casein preparation was assessed in Wistar rats pair-fed for 4 wk with three identical diets differing only by the type of casein used. Compared with dietary casein and Na caseinate, ingestion of lipid- and vitamin-free casein resulted in higher liver weights (4.35 +/- 0.23 vs. 3.89 +/- 0.30 and 3.90 +/- 0.25 g) and fasting serum cholesterol levels (0.55 +/- 0.13 vs. 0.49 +/- 0.09 and 0.44 +/- 0.09 g/L). Compared with the two other casein diets, ingestion of Na caseinate produced the lowest fasting serum triglyceride levels (0.62 +/- 0.13 vs 0.74 +/- 0.12 and 0.73 +/- 0.13 g/L). Peptic digestibility of caseins used might be a regulating factor of serum cholesterol levels in Wistar rats.
authors.affiliation: INSERM U.308, Nancy, France.
authors.forename: L
authors.initials: L
authors.lastname: Guermani
authors.forename: C
authors.initials: C
authors.lastname: Villaume
authors.forename: H M
authors.initials: HM
authors.lastname: Bau
authors.forename: L
authors.initials: L
authors.lastname: Mejean
authors.forename: J P
authors.initials: JP
authors.lastname: Nicolas
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D002364:Caseins / Q000494:pharmacology*; D002784:Cholesterol / Q000097:blood*; D004044:Dietary Proteins / Q000494:pharmacology*; D050356:Lipid Metabolism; D008099:Liver / Q000187:drug effects; D008297:Male; D016555:Matched-Pair Analysis; D011817:Rabbits; D051381:Rats; D011919:Rats, Inbred Strains; D014280:Triglycerides / Q000097:blood*; D014815:Vitamins / Q000378:metabolism
chemical_list: D001786:Blood Glucose; D002364:Caseins; D004044:Dietary Proteins; D014280:Triglycerides; D014815:Vitamins; D002784:Cholesterol