[Aneurysm at the base of the brain and tuberous sclerosis].
Reported is the rare case of intracranial aneurysm in a boy aged one year with tuberous sclerosis. Inconspicuous development in the first few months after birth was followed, in the sixth month of age, by aggravating manifestation of convulsive seizures which were clinically diagnosed as tuberous sclerosis. Rapid progression of the clinical pattern was preterminally followed by cerebral haemorrhage which was caused by circumscribed, partially purulent arteritis along with formation of a mycotic aneurysm on the anterior segments of the arterial circle of Willis. The development of this aneurysm is discussed in conjunction with the morphological and clinical findings of tuberous sclerosis.
Engel
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Abteilung für Neuropathologie am Institut für Pathologie, Medizinische Fakultät (Charité), Humboldt-Universität zu Berlin, Deutschland.
D000785:Aneurysm, Infected / Q000150:complications / Q000473:pathology*; D002543:Cerebral Hemorrhage / Q000209:etiology* / Q000473:pathology; D002941:Circle of Willis; D006801:Humans; D007223:Infant; D002532:Intracranial Aneurysm / Q000150:complications / Q000473:pathology*; D008297:Male; D012422:Rupture, Spontaneous; D014402:Tuberous Sclerosis / Q000150:complications*
Hirnbasisaneurysma und tuberöse Hirnsklerose.