[Spinal leptomeningeal tumor spread disclosing a pineocytoma].
A 39-year-old female was admitted to the hospital because of a sudden meningeal syndrome followed by diplopia, cervical, dorsal and sciatic nerve pains, and right peripheral facial palsy. Cerebrospinal fluid obtained by lumbar puncture showed a protein level at 23 g/l. Myelography and magnetic resonance imaging (MRI) were in favor of a lumbar arachnoiditis. A meningeal biopsy revealed a tumour infiltration with foci of cells that were stained with anti-glial fibrillary acidic protein antibody. Cerebral MRI was performed to search for a central nervous system (CNS) primary tumour, and disclosed a pineal mass. Five months after the onset of the disease, the patient worsened her clinical state and died. Necropsy confirmed the presence of a pineocytoma with astrocytic differentiation and diffuse leptomeningeal spread. This exceptional occurrence leads us to discuss about primary tumours of the CNS with leptomeningeal spread.
Pasquier
B
B
Service d'Anatomie Pathologique, Hôpital Albert Michallon.
Le Marc'Hadour
F
F
Dieny
A
A
Ciapa
A
A
Lefrancq
T
T
Bost
F
F
Martal
S
S
Micoud
M
M
Pasquier
D
D
D000328:Adult; D001099:Arachnoid; D001706:Biopsy; D001932:Brain Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000556:secondary*; D010870:Pineal Gland; D010871:Pinealoma / Q000556:secondary*
Essaimage tumour leptomeninge spinal révélateur d'un pineocytome.