The role of serotonergic system in body temperature regulation.
Results indicate that vascular responses to temperature stimulation are predominantly impaired in animals with 5-HT deprivation. A hypothesis is therefore raised that the 5-HT system participates in body temperature regulation in such a way as to link the regulatory output with vasomotor pathways. The 5-HT system in the spinal cord has been shown to inhibit the afferent transmission of temperature signals. Therefore, depletion of 5-HT does not prevent sensory transmission, at least at the spinal cord level.
Nagai
M
M
Department of Physiology, Medical University of Yamanashi, Japan.
D015116:5,7-Dihydroxytryptamine / Q000494:pharmacology; D000818:Animals; D001341:Autonomic Nervous System / Q000502:physiology; D001833:Body Temperature Regulation / Q000502:physiology*; D011817:Rabbits; D012701:Serotonin / Q000502:physiology*; D013116:Spinal Cord / Q000502:physiology; D014666:Vasomotor System / Q000502:physiology
D015116:5,7-Dihydroxytryptamine; D012701:Serotonin