Advantages and guidelines for using opioid agonist-antagonist analgesics.
The opioid agonist-antagonists are not controlled substances requiring strict record keeping and security because of their low abuse potential. They are effective analgesics in their own right and can be used to antagonize opioid agonist-induced depression while retaining a degree of analgesia. Respiratory depression is less than that induced by opioid agonists, but degree of analgesia is somewhat limited also owing to the ceiling effect.
Benson
G J
GJ
Department of Anesthesiology, University of Illinois, College of Veterinary Medicine, Urbana.
Tranquilli
W J
WJ
D000698:Analgesia / Q000662:veterinary*; D000700:Analgesics / Q000627:therapeutic use*; D000818:Animals; D009292:Narcotic Antagonists / Q000627:therapeutic use*
D000700:Analgesics; D009292:Narcotic Antagonists