title: Hematopoiesis.
abstract: Hematopoiesis begins with the pluripotent stem cell in the marrow and culminates in mature, functional red blood cells, white blood cells, and platelets in the circulation. The process consists of a complex and well-orchestrated sequence of cell proliferation, differentiation, and maturation, that is stimulated and regulated by a host of cytokines and hormones. The various growth factors act individually and in concert at different stages of hematopoiesis and have important effects on mature cell function.
authors.affiliation: Department of Pharmacy Practice, College of Pharmacy, University of Florida, Gainesville 32610.
authors.forename: S P
authors.initials: SP
authors.lastname: Smith
authors.forename: G C
authors.initials: GC
authors.lastname: Yee
mesh_terms: D001792:Blood Platelets / Q000166:cytology; D001854:Bone Marrow Cells; D016207:Cytokines / Q000502:physiology; D004920:Erythropoiesis; D006098:Granulocytes / Q000166:cytology; D006410:Hematopoiesis; D016298:Hematopoietic Cell Growth Factors / Q000502:physiology; D006412:Hematopoietic Stem Cells / Q000166:cytology; D006801:Humans; D008214:Lymphocytes / Q000166:cytology; D008264:Macrophages / Q000166:cytology
chemical_list: D016207:Cytokines; D016298:Hematopoietic Cell Growth Factors