title: The influence of age on supraoptic nucleus neurons of the rat: morphometric and morphologic changes.
abstract: Neurosecretory neurons (NSNs) of the supraoptic nucleus of 2-year-old rats presented significantly greater nuclear volumes and nuclear perimeters than those of 3-month-old animals. In aged NSNs, membranous bodies (MBs) were observed in the cytoplasm and the cell nucleus. The possible origin and function of these MBs are discussed.
authors.affiliation: Department of Anatomy and Cell Biology, Faculty of Medicine, University of Cantabria, Santander, Spain.
authors.forename: D
authors.initials: D
authors.lastname: Crespo
authors.forename: C
authors.initials: C
authors.lastname: Fernández-Viadero
authors.forename: C
authors.initials: C
authors.lastname: González
mesh_terms: D000375:Aging / Q000473:pathology*; D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D007425:Intracellular Membranes / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D009474:Neurons / Q000166:cytology; D051381:Rats; D011919:Rats, Inbred Strains; D013495:Supraoptic Nucleus / Q000166:cytology*