title: Kininogen changes in the alloxan-diabetic rat.
abstract: Ten-day alloxan diabetic rats showed substantial increases in plasma T-kininogen, high molecular and low molecular weight kininogens, as well as significant decreases in urinary levels of kallikrein. Changes in T-kininogen were also observed following turpentine inflammatory treatment. In the diabetic rat, inflammatory responses may contribute to T-kininogen increases.
authors.affiliation: Department of Physics and Chemistry, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Brazil.
authors.forename: M L
authors.initials: ML
authors.lastname: Reis
authors.forename: R
authors.initials: R
authors.lastname: Paschoalato
authors.forename: C H
authors.initials: CH
authors.lastname: Serra
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism* / Q000652:urine; D007610:Kallikreins / Q000652:urine; D007704:Kininogens / Q000097:blood / Q000378:metabolism* / Q000652:urine; D008297:Male; D008969:Molecular Sequence Data; D051381:Rats
chemical_list: D001786:Blood Glucose; D007704:Kininogens; D007610:Kallikreins