Angiosarcoma of the thigh with thrombosis in the femoral artery.
We report a case of angiosarcoma with some peculiar clinical features developing on the left thigh of a 63-year-old man. The early primary lesion was erythematous with necrotic areas. The initial biopsy specimen of the lesion indicated a benign angioproliferative process. However, the necrotic area enlarged rapidly, ulcerated with severe pain, and thus was widely excised. The excised specimen had a malignant histologic appearance, particularly in the fascia, and was diagnosed as angiosarcoma. Following local recurrence, the lesion was complicated by thrombosis of the femoral artery at the affected site. A similar cutaneous lesion subsequently arose on the right lower leg, and thrombosis developed in the right femoral artery. Both legs had to be amputated. There were no distant metastases.
Miyamoto
T
T
Department of Dermatology, Tsuyama Central Hospital, Japan.
Mihara
M
M
Iwasaki
K
K
Mishima
E
E
Shimao
S
S
Miyamoto
H
H
D000671:Amputation, Surgical; D005263:Femoral Artery; D006394:Hemangiosarcoma / Q000150:complications* / Q000648:ultrastructure; D006801:Humans; D007866:Leg / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009336:Necrosis / Q000209:etiology; D012878:Skin Neoplasms / Q000150:complications* / Q000648:ultrastructure; D013848:Thigh; D013927:Thrombosis / Q000209:etiology*