title: (-)-agelasidine C and (-)-agelasidine D, two new hypotaurocyamine diterpenoids from the Caribbean sea sponge Agelas clathrodes.
abstract: Two new diterpene derivatives of hypotaurocyamine, (-)-agelasidine C [3] and (-)-agelasidine D [5], have been isolated from the Caribbean sea sponge Agelas clathrodes. The structures of 3 and 5 have been established by interpretation and comparison of their spectral data to those of the known antipode (+)-agelasidine C [1].
authors.affiliation: Department of Chemistry, University of Puerto Rico, Río Piedras 00931.
authors.forename: J J
authors.initials: JJ
authors.lastname: Morales
authors.forename: A D
authors.initials: AD
authors.lastname: Rodríguez
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D004224:Diterpenes / Q000302:isolation & purification* / Q000494:pharmacology*; D006146:Guanidines / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D011161:Porifera / Q000502:physiology*; D014407:Tumor Cells, Cultured
chemical_list: D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D004224:Diterpenes; D006146:Guanidines; C074726:agelasidine D; C054173:agelasidine C