Isolation and characterization of tributyltin chloride-resistant marine Vibrio.
Tributyltin chloride (TBTCl)-resistant marine bacteria were isolated from coastal sea water. One of these bacteria (Vibrio M-1) was highly resistant when grown in medium containing 125 microM of TBTCl. This strain was sensitive to other metals. Two polypeptides, 30 kDa and 12 kDa, increased when the strain was cultured in the medium supplemented with TBTCl. Initially TBTCl was taken up by the cell; however, the amount of TBTCl determined in the cellular fraction was low after the exponential growth phase of Vibrio M-1, suggesting the existence of a TBTCl-efflux system.
Fukagawa
T
T
Department of Food Science and Technology, Faculty of Fisheries, Hokkaido University, Japan.
Suzuki
S
S
Fukunaga
K
K
Suzuki
T
T
Takama
K
K
D001692:Biological Transport; D004352:Drug Resistance, Microbial; D012623:Seawater; D014220:Trialkyltin Compounds / Q000378:metabolism / Q000494:pharmacology*; D014733:Vibrio / Q000187:drug effects* / Q000302:isolation & purification / Q000378:metabolism; D014871:Water Microbiology
D014220:Trialkyltin Compounds; C011559:tributyltin