Haemodialysis-related porphyria cutanea tarda and treatment by recombinant human erythropoietin.
Haemodialysis-related porphyria cutanea tarda is a rare, but serious and mutilating skin condition, resulting from extremely high plasma porphyrin levels because of their inadequate clearance by haemodialysis. The treatment is very difficult as chloroquine is ineffective and venesection, the conventional treatment of this disease, is not always an option because of anaemia of end-stage renal disease. We report a case of haemodialysis-related porphyria cutanea tarda and her successful management by recombinant human erythropoietin treatment.
Yaqoob
M
M
Regional Renal Unit, Royal Liverpool Hospital, UK.
Smyth
J
J
Ahmad
R
R
McClelland
P
P
Fahal
I
I
Kumar
K A
KA
Yu
R
R
Verbov
J
J
D004921:Erythropoietin / Q000627:therapeutic use; D005260:Female; D005293:Ferritins / Q000097:blood; D006801:Humans; D008875:Middle Aged; D011164:Porphyrias / Q000097:blood / Q000188:drug therapy / Q000209:etiology*; D011166:Porphyrins / Q000097:blood; D006435:Renal Dialysis / Q000009:adverse effects*; D012871:Skin Diseases / Q000097:blood / Q000188:drug therapy / Q000209:etiology*
D011166:Porphyrins; D004921:Erythropoietin; D005293:Ferritins