title: [The incorporation of acyclovir into the treatment of peripheral paralysis. A study of 45 cases].
abstract: The relation between use of acyclovir and facial nerve palsy prognosis was studied. In a randomised study, steroids or steroids + acyclovir (oral doses for Bell's palsy, and intravenous doses for Ramsay Hunt's syndrome) were given to 45 patients with facial palsy. There was a significant reduction of sequelae in patients treated with acyclovir in the group of Ramsay Hunt's syndrome (n = 15) (p less than 0.05). There were no significant differences in the group of Bell's palsy (n = 30) (p greater than 0.05), treated with acyclovir compared with steroids.
authors.affiliation: Servicio de ORL, Hospital Clínico Universitario de Salamanca.
authors.forename: A
authors.initials: A
authors.lastname: Ramos Macías
authors.forename: I
authors.initials: I
authors.lastname: de Miguel Martínez
authors.forename: A M
authors.initials: AM
authors.lastname: Martín Sánchez
authors.forename: J L
authors.initials: JL
authors.lastname: Gómez González
authors.forename: A
authors.initials: A
authors.lastname: Martín Galán
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use*; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005158:Facial Paralysis / Q000175:diagnosis / Q000188:drug therapy*; D016697:Herpes Zoster Oticus / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D011379:Prognosis
chemical_list: D000305:Adrenal Cortex Hormones; D000212:Acyclovir
vernacular_title: Incorporación del aciclovir en el tratamiento de la parálisis periférica. Un estudio en 45 casos.