DNA fingerprinting in leukemia.
The detection of polymorphic regions of the human DNA provides individual specific markers, DNA fingerprints (DNA-F), for the identification of individuals. DNA-F can also be used for the detection of cell clones and serve as molecular markers of malignant disease. In leukemia DNA-F analysis can be used for the follow-up studies during remission or after bone marrow transplantation. Recent studies on DNA fingerprinting in leukemia are reviewed.
Pakkala
S
S
Transplantation Laboratory, University of Helsinki, Finland.
D001483:Base Sequence; D014408:Biomarkers, Tumor; D002999:Clone Cells / Q000737:chemistry; D016172:DNA Fingerprinting; D015342:DNA Probes; D004273:DNA, Neoplasm / Q000235:genetics*; D005819:Genetic Markers; D006801:Humans; D007938:Leukemia / Q000235:genetics* / Q000628:therapy; D008969:Molecular Sequence Data; D014411:Neoplastic Stem Cells / Q000737:chemistry; D012680:Sensitivity and Specificity
D014408:Biomarkers, Tumor; D015342:DNA Probes; D004273:DNA, Neoplasm; D005819:Genetic Markers