The use of nuclear magnetic resonance imaging in monitoring total body iron in hemodialysis patients with hemosiderosis treated with erythropoietin and phlebotomy.
Two hemodialysis patients with hemosiderosis were treated with combined erythropoietin and repeated phlebotomy. Serial nuclear magnetic resonance (NMR) imaging and serum ferritin levels were used to monitor the efficacy of treatment. This treatment modality has definite advantages over chronic deferoxamine therapy. NMR image-derived parameters offer an objective, accurate, and noninvasive indication of tissue iron stores.
Chan
P C
PC
Divisions of Nephrology, Toronto Hospital, University of Toronto, Ontario, Canada.
Liu
P
P
Cronin
C
C
Heathcote
J
J
Uldall
R
R
D000328:Adult; D000368:Aged; D001815:Bloodletting; D004921:Erythropoietin / Q000627:therapeutic use; D005260:Female; D005293:Ferritins / Q000097:blood; D006486:Hemosiderosis / Q000097:blood / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D006801:Humans; D007501:Iron / Q000032:analysis*; D008099:Liver / Q000737:chemistry / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D009206:Myocardium / Q000737:chemistry / Q000473:pathology; D006435:Renal Dialysis / Q000009:adverse effects*
D004921:Erythropoietin; D005293:Ferritins; D007501:Iron