title: In vitro adherence property of cytolethal distending toxin (CLDT) producing EPEC strains and effect of the toxin on rabbit intestine.
abstract: Sixteen cytolethal distending toxin-producing enteropathogenic Escherichia coli (CLDT+ EPEC) strains of six different serogroups were included in this study. The strains showed varying adherence patterns on HEp-2 cells, i.e. six strains showed localized adherence (LA), five strains exhibited diffuse adherence (DA) and five strains were non-adherent. Histological study of rabbit ileal segments showed that live cultures of CLDT+ EPEC did not cause lesions characteristic of attachment and effacement (AE) and the toxin effect resembled that of classical LT or CT.
authors.affiliation: Department of Microbiology, Maulana Azad Medical College, New Delhi, India.
authors.forename: S
authors.initials: S
authors.lastname: Bouzari
authors.forename: B R
authors.initials: BR
authors.lastname: Vatsala
authors.forename: A
authors.initials: A
authors.lastname: Varghese
mesh_terms: D000818:Animals; D001422:Bacterial Adhesion; D001427:Bacterial Toxins / Q000378:metabolism*; D002478:Cells, Cultured; D004926:Escherichia coli / Q000378:metabolism / Q000502:physiology*; D004927:Escherichia coli Infections / Q000382:microbiology; D007082:Ileum / Q000382:microbiology* / Q000473:pathology; D011817:Rabbits
chemical_list: D001427:Bacterial Toxins; C067044:cytolethal distending toxin