title: [Reliable Quick value management by self determination].
abstract: Because of the considerably increased risk of thrombembolic complications after implantation of mechanical heart valves, lifelong anticoagulation is required. In the face of frequently unsteady prothrombin-time (PT)-values, a stable anticoagulation is one of the most difficult tasks in attending patients with heart-valve-prosthesis. If PT is out of the therapeutic range, the risk of bleeding or of thrombembolism increases disproportionately. Two differently trained groups of phenprocoumon-treated patients monitored their PT themselves for 6 months by means of a coagulometer, and they also determined their weekly dose of phenprocoumon. PTs were therapeutic 80.5% resp. 93.8% of the time. Intensive training and care maximized safety of anticoagulation.
authors.affiliation: Kardiologische Abt. Fachklinik Rhein-Ruhr, Essen-Kettwig.
authors.forename: F J
authors.initials: FJ
authors.lastname: Wittstamm
authors.forename: L
authors.initials: L
authors.lastname: Benesch
mesh_terms: D003374:Coumarins / Q000008:administration & dosage; D006350:Heart Valve Prosthesis; D006801:Humans; D011183:Postoperative Complications / Q000097:blood* / Q000517:prevention & control; D011517:Prothrombin Time; D012307:Risk Factors; D012648:Self Care / Q000295:instrumentation*; D013923:Thromboembolism / Q000097:blood* / Q000517:prevention & control
chemical_list: D003374:Coumarins; C030123:coumarin
vernacular_title: Sicheres Quickwert-Management durch Selbstbestimmung.