title: Effect of dilantin on myocardial uptake of Tl-201 thallous chloride. A case report.
abstract: Dilantin has been reported to decrease myocardial uptake of Tl-201 thallous chloride by as much as 38.8% in rats. To date, no studies have been done in humans to document the effect of dilantin on the myocardial uptake of thallium or its effect clinically on the interpretation of images obtained while on dilantin. The authors report a case in which simultaneous exercise echocardiogram and Tl-201 myocardial scintigraphy and serial Tl-201 myocardial scintigraphy were performed but revealed no adverse effect on image quality or interpretation.
authors.affiliation: Department of Radiology, Brooke Army Medical Center, San Antonio, Texas 78234.
authors.forename: S E
authors.initials: SE
authors.lastname: Budd
authors.forename: L B
authors.initials: LB
authors.lastname: Padove
authors.forename: J D
authors.initials: JD
authors.lastname: Heironimus
mesh_terms: D000368:Aged; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D004452:Echocardiography; D005080:Exercise Test; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D010672:Phenytoin / Q000494:pharmacology* / Q000627:therapeutic use; D011877:Radionuclide Imaging; D012640:Seizures / Q000188:drug therapy; D013793:Thallium; D013794:Thallium Radioisotopes
chemical_list: D013794:Thallium Radioisotopes; C027549:thallium chloride; D010672:Phenytoin; D013793:Thallium