Bruton-type (congenital X-linked) agammaglobulinemia: MR imaging of unusual intracranial complications.
The authors describe two patients with Bruton-type agammaglobulinemia, their purpose being to indicate the spectrum of findings, clinical and imaging. MR in one patient revealed diffuse leptomeningeal enhancement in the brain and spine; in the second patient, a heterogeneous mass was seen that had broken through the basiocciput and displaced a cerebellar hemisphere. Awareness of the common and unusual CNS manifestations of this disease can impact clinical management.
Lerner
E J
EJ
Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104.
Bilaniuk
L T
LT
D000328:Adult; D000361:Agammaglobulinemia / Q000150:complications* / Q000151:congenital / Q000235:genetics; D001927:Brain Diseases / Q000175:diagnosis* / Q000209:etiology; D004338:Drug Combinations; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008536:Meglumine; D008587:Meningitis, Viral / Q000175:diagnosis / Q000209:etiology; D009942:Organometallic Compounds; D004369:Pentetic Acid
D004338:Drug Combinations; D009942:Organometallic Compounds; D008536:Meglumine; D004369:Pentetic Acid; D019786:Gadolinium DTPA