title: Epidural blood patch in the HIV-positive patient. Review of clinical experience. San Diego HIV Neurobehavioral Research Center.
abstract: To characterize the natural history of autologous epidural blood patch (EBP) in human immunodeficiency virus (HIV)-seropositive patients, records from an ongoing longitudinal study of the neuropsychological manifestations of HIV infection were retrospectively reviewed. Of 252 participants (218 HIV-seropositive, 34 HIV-seronegative) who underwent at least one diagnostic lumbar puncture, 9 (7 seropositive, 2 seronegative) required EBP for post-dural puncture headache. After EBP, 6 of the seropositive subjects underwent serial neuropsychological evaluations over periods ranging from 6 to 24 months; none of these six subjects had a decline in neurocognitive performance or other adverse neurologic or infectious sequelae. We were unable to identify morbidity attributable to EBP in the HIV-seropositive patient followed for as long as 2 yr.
authors.affiliation: Department of Anesthesiology, University of California, San Diego, Medical Center 92103.
authors.forename: D J
authors.initials: DJ
authors.lastname: Tom
authors.forename: S J
authors.initials: SJ
authors.lastname: Gulevich
authors.forename: H M
authors.initials: HM
authors.lastname: Shapiro
authors.forename: R K
authors.initials: RK
authors.lastname: Heaton
authors.forename: I
authors.initials: I
authors.lastname: Grant
mesh_terms: D000328:Adult; D001769:Blood; D006679:HIV Seropositivity; D006261:Headache / Q000209:etiology / Q000628:therapy*; D006801:Humans; D007268:Injections, Epidural; D008297:Male; D013129:Spinal Puncture / Q000009:adverse effects*