Isodicentric chromosome 18 in an abnormal infant using chromosome specific DNA probe.
A report is made on a rare isodicentric chromosome 18 in an abnormal male infant whose karyotype was 46,XY,idic(18)(p11.31----qter), confirmed by in situ hybridization using non-radioactive biotin-labelled 18 probe. His clinical features were similar to 18 trisomy syndrome. The literature concerning isochromosome 18 is reviewed.
Meguid
N A
NA
Human Genetics Dept. of National Research Center, Egypt.
Habibian
R
R
D000015:Abnormalities, Multiple / Q000235:genetics*; D002503:Centromere / Q000648:ultrastructure*; D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D002887:Chromosomes, Human, Pair 18; D015342:DNA Probes; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male; D009693:Nucleic Acid Hybridization
D015342:DNA Probes