[Unilateral systematic linear porokeratosis. Immuno- and lectin histochemistry].
An uncommon case of unilateral systemic linear porokeratosis in a women aged 22 years is reported in this paper. The results obtained from frozen-section investigations into lectin binding were indicative of reduced epidermal fucosylation and sialinization beneath the cornoid lamella. The basal stratum failed to react with a polyclonal antibody against calmodulin. Epidermal reaction, with AS-6 staining against urokinase, was of higher intensity. The above findings, as a whole, are likely to suggest accelerated keratinocyte migration to the stratum corneum in cases of linear porokeratosis and and should actually support assignment of the latter to the group of dermatoses with transepidermal elimination.
Wollina
U
U
Klinik und Poliklinik für Hautkrankheiten, Medizinischen Fakultät, Friedrich-Schiller-Universität Jena, Deutschland.
Henkel
U
U
Schaarschmidt
H
H
Hipler
C
C
D000328:Adult; D004817:Epidermis / Q000737:chemistry / Q000473:pathology*; D005260:Female; D005455:Fluorescent Antibody Technique; D005629:Frozen Sections; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D007642:Keratosis / Q000473:pathology*; D037102:Lectins
D037102:Lectins
Unilaterale systematische lineäre Porokeratose. Immun- und Lektinhistochemie.