Formulation optimization of sustained-release tablet of chlorpheniramine maleate by means of extreme vertices design and simultaneous optimization technique.
Hirata
M
M
Department of Pharmaceutics, Hoshi University, Tokyo, Japan.
Takayama
K
K
Nagai
T
T
D002482:Cellulose; D002626:Chemistry, Pharmaceutical; D002744:Chlorpheniramine; D003198:Computer Simulation; D003692:Delayed-Action Preparations; D011205:Povidone; D013607:Tablets; D014753:Vinyl Compounds
D003692:Delayed-Action Preparations; D013607:Tablets; D014753:Vinyl Compounds; D002744:Chlorpheniramine; D002482:Cellulose; D011205:Povidone