[The mechanisms of lymphoid regulation and the radiosensitivity of the hematopoietic system].
On the basis of the authors' own data and the literature it has been inferred that the key principles of the haemopoietic system regulation are similar to those of the immune system. The cells of a lymphoid origin are found, which implement helper and suppressor functions with respect to early haemopoiesis precursors; the influence of lymphokines on this compartment under the effect of radiation is described. Disturbances in the haemopoiesis system regulation, that result from various damaging effects, might be corrected by T-lymphocytes and lymphokines. The data obtained suggest that the formation of splenic colonies is the result of the interaction of some cell populations. That is why many radiobiological characteristics of CFUs may be attributed to partner cells (for instance, T-lymphocytes).
Semina
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Semenets
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Poverennyĭ
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D000818:Animals; D002455:Cell Division / Q000528:radiation effects; D003114:Colony-Forming Units Assay; D006413:Hematopoietic System / Q000166:cytology / Q000528:radiation effects*; D008214:Lymphocytes / Q000166:cytology / Q000528:radiation effects*; D008222:Lymphokines / Q000502:physiology / Q000528:radiation effects; D011836:Radiation Tolerance; D013601:T-Lymphocytes / Q000166:cytology / Q000528:radiation effects; D013997:Time Factors
D008222:Lymphokines
Mekhanizmy limfoidnoĭ reguliatsii i radiochuvstvitel'nost' sistemy krovetvoreniia.