Spinal anaesthesia for caesarean section: 0.125% plain bupivacaine 12 ml compared with 0.5% plain bupivacaine 3 ml.
Forty women had elective Caesarean section under spinal anaesthesia with either 0.5% bupivacaine 3 ml or 0.125% bupivacaine 12 ml, injected at a rate of 1 ml/5 s. For 30 min after the spinal injection, each patient lay on her right side. Compared with the patients given 3 ml, in those given bupivacaine 12 ml there was a significantly greater spread of block (P less than 0.02 for analgesia; P less than 0.002 for touch) and significantly less variation in levels of block (P less than 0.02 for analgesia; P less than 0.04 for touch). However, within 5 min of placing the women in a supine, tilted (right hip up) position, there were no clinically or statistically significant differences in the levels of block between the two groups.
Vucevic
M
M
Department of Anaesthesia, Hull Royal Infirmary.
Russell
I F
IF
D000328:Adult; D000773:Anesthesia, Obstetrical; D000775:Anesthesia, Spinal; D002045:Bupivacaine / Q000008:administration & dosage*; D002585:Cesarean Section; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D011187:Posture; D011247:Pregnancy; D013997:Time Factors
D002045:Bupivacaine