title: Staging and prognostic factors in carcinoma of the base of the tongue.
abstract: During the period 1966-1985, 66 patients were submitted for curative treatment of a carcinoma of the base of the tongue in the Netherlands Cancer Institute. Treatment consisted of radiotherapy (59 patients), surgery and post-operative radiotherapy (4 patients) and surgery alone (3 patients). Patients were staged according to the UICC (1982) and UICC (1987)/AJCC (1988) criteria. Regrouping by the latter system caused enlargement of the N2-group and of stage IV. The crude 5-year survival was 22%, the 5-year tumour control was 36% and the locoregional control was 47%. The most important prognostic factors for the tumour-free interval are the T-category (P = 0.01) and stage grouping (UICC 1982) (P = 0.022). The same factors predict the locoregional control (P = 0.005 and 0.02 respectively). Crude survival is lower in smokers, and in patients in poor general condition (P = 0.04 and 0.007 respectively).
authors.affiliation: Departments of ENT/Head and Neck Surgery, The Netherlands Cancer Institute, Amsterdam.
authors.forename: S
authors.initials: S
authors.lastname: Mak-Kregar
authors.forename: P F
authors.initials: PF
authors.lastname: Schouwenburg
authors.forename: G
authors.initials: G
authors.lastname: Baris
authors.forename: F J
authors.initials: FJ
authors.lastname: Hilgers
authors.forename: A A
authors.initials: AA
authors.lastname: Hart
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000145:classification / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009333:Neck; D009367:Neoplasm Staging; D011182:Postoperative Care; D011379:Prognosis; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy; D012189:Retrospective Studies; D016879:Salvage Therapy; D012907:Smoking; D015996:Survival Rate; D014062:Tongue Neoplasms / Q000145:classification / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*