title: MHC class II expression in the bovine mammary gland.
abstract: The distribution of major histocompatibility complex (MHC) class II positive cells within the connective tissue and the epithelium of the involuted bovine mammary gland has been determined. The effect of intramammary administration of the antigens ovalbumin and formalin killed Streptococcus uberis on the distribution pattern has also been investigated. Infusion of formalin killed S. uberis increased cellular expression of class II antigens when compared with quarters either infused with ovalbumin, not infused at all, or from which minor pathogens had been isolated. The increased expression occurred particularly in the area of the gland cistern-secretory tissue junction.
authors.affiliation: Department of Veterinary Medicine, University of Bristol, School of Veterinary Science, Langford, UK.
authors.forename: J L
authors.initials: JL
authors.lastname: Fitzpatrick
authors.forename: P J
authors.initials: PJ
authors.lastname: Cripps
authors.forename: A W
authors.initials: AW
authors.lastname: Hill
authors.forename: P W
authors.initials: PW
authors.lastname: Bland
authors.forename: C R
authors.initials: CR
authors.lastname: Stokes
mesh_terms: D000818:Animals; D002417:Cattle / Q000276:immunology*; D003238:Connective Tissue / Q000378:metabolism; D004848:Epithelium / Q000378:metabolism; D005260:Female; D000949:Histocompatibility Antigens Class II / Q000032:analysis*; D007111:Immunity, Cellular; D007124:Immunoenzyme Techniques; D008321:Mammary Glands, Animal / Q000276:immunology*; D008414:Mastitis, Bovine / Q000276:immunology*; D010047:Ovalbumin / Q000276:immunology; D013291:Streptococcus / Q000276:immunology
chemical_list: D000949:Histocompatibility Antigens Class II; D010047:Ovalbumin