The St. George's dementia bed investigation study: a comparison of clinical and pathological diagnosis.
Sixty-four elderly patients who had been admitted to the St. George's Hospital Alzheimer's disease evaluation project during 1981-1989 were followed up to postmortem examination. Comparison between clinical diagnoses and neuropathological diagnoses indicated positive predictive values for the antemortem diagnoses of 50-67%. Existing clinical criteria may not be accurate enough to permit firm antemortem diagnosis of older people for either research or clinical purposes.
Gilleard
C J
CJ
Department of Geriatric Medicine, St. George's Hospital Medical School, Tooting, London, United Kingdom.
Kellett
J M
JM
Coles
J A
JA
Millard
P H
PH
Honavar
M
M
Lantos
P L
PL
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D001921:Brain / Q000473:pathology; D003430:Cross-Sectional Studies; D015161:Dementia, Multi-Infarct / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D003937:Diagnosis, Differential; D004739:England / Q000453:epidemiology; D005260:Female; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D008297:Male; D009483:Neuropsychological Tests