[Dendrite-morphometry of lamina-V-pyramidal cells in premature brain damaged humans--a Golgi study].
Specimens from the area 10 of the frontal cortex collected out of 7 patients with severe mental retardation, aged 3 to 24 years and also 8 non-neuropsychiatric age-matched controls were processed according to the Golgi-Kopsch method. The total length of the apical side-dendrites and of the basal dendrites was measured on layer V pyramidal neurons. Compared with controls the total dendritic length of the apical side-dendrites as well as of the basal dendrites was significant reduced in the affected patients (p less than 0.001). The reduced dendritic length represents perhaps a morphological correlate to the mental dysfunction.
von Bossányi
P
P
Abteilung Neuropathologie, Medizinischen Akademie Magdeburg.
Schmitt
J A
JA
Dietzmann
K
K
D000293:Adolescent; D000328:Adult; D001925:Brain Damage, Chronic / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D003712:Dendrites / Q000648:ultrastructure*; D005260:Female; D005625:Frontal Lobe / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D011712:Pyramidal Tracts / Q000473:pathology*
Dendriten-Morphometrie von Lamina-V-Pyramidenzellen bei frühkindlicher Hirnschädigung--eine Golgi-Studie.