title: [Synthesis of alpha-chrysanthemylmethyl-gamma- and delta-lactones with cytostatic activity].
abstract: The synthesis of the alpha-chrysanthemylmethylen-gamma- and delta-lactones 7-9, 11, 12 from the lactones 1-3, 5 and that of 10 from 2-oxo-chroman (4) and the aldehyd 6 is described. The compounds 7-9 and 11, 12 show cytostatic activity.
authors.affiliation: Dipartimento di Scienze Farmaceutiche, Università degli Studi di Trieste, Trieste, Italia.
authors.forename: G
authors.initials: G
authors.lastname: Falsone
authors.forename: F
authors.initials: F
authors.lastname: Cateni
authors.forename: A
authors.initials: A
authors.lastname: el-Alali
authors.forename: A
authors.initials: A
authors.lastname: Papaioannau
authors.forename: L
authors.initials: L
authors.lastname: Ravalico
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D006801:Humans; D007783:Lactones / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D011722:Pyrethrins / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D014407:Tumor Cells, Cultured / Q000187:drug effects
chemical_list: D000970:Antineoplastic Agents; D007783:Lactones; D011722:Pyrethrins
vernacular_title: Synthese von alpha-Chrysanthemylmethylen-gamma- und delta-Lactonen mit zytostatischer Wirkung.