title: [Chemotherapy and thymostimulin in the treatment of advanced-stage breast neoplasms].
abstract: In this study, we have evaluated certain haematologic and immunologic parameters in two advanced disease patient groups treated with chemotherapy (CMF schedule)+thymostimulin or chemotherapy alone, respectively. Statistical analysis of the data does not reveal any significant difference between the two patient groups. In our opinion, however, the administration of thymic hormone seems to protect the marrow crasis and, as a consequence, to obtain a lower incidence of side effects and respect of chemotherapeutic schedule.
authors.affiliation: Cattedra di Oncologia Medica, Università degli Studi di Torino.
authors.forename: L
authors.initials: L
authors.lastname: Negri
authors.forename: F
authors.initials: F
authors.lastname: Calabrese
authors.forename: F
authors.initials: F
authors.lastname: Correggia
authors.forename: S
authors.initials: S
authors.lastname: Miozzo
authors.forename: S
authors.initials: S
authors.lastname: Giacomasso
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy / Q000276:immunology / Q000628:therapy*; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008207:Lymphatic Metastasis; D008213:Lymphocyte Activation; D016131:Lymphocyte Subsets / Q000276:immunology; D008727:Methotrexate / Q000627:therapeutic use; D008875:Middle Aged; D009362:Neoplasm Metastasis; D013949:Thymus Extracts / Q000627:therapeutic use*
chemical_list: D000276:Adjuvants, Immunologic; D007136:Immunoglobulins; D013949:Thymus Extracts; C031407:thymostimulin; D003520:Cyclophosphamide; D005472:Fluorouracil; D008727:Methotrexate
vernacular_title: Chemioterapia e timostimolina nel trattamento della neoplasia mammaria in fase avanzata.