Is there any correlation between follicular fluid hormone concentrations, fertilizability, and cytogenetic analysis of human oocytes recovered for in vitro fertilization?
Constituents of FF have been suspected to influence fertilizability and cytogenetic constitution of human oocytes. We therefore analyzed the FF concentrations of E2, P, T, and PRL for 114 oocytes recovered for IVF. Forty-six of these oocytes were fertilized and transferred to the maternal uterus. Among the unfertilized gametes, 27 were not analyzable, 30 were normal haploid, and 11 were classified as abnormal. There was no significant difference between fertilized and unfertilized oocytes for FF concentrations of E2, P, T, and PRL and for the E2:P ratios. Similarly, we detected no significant difference between normal and abnormal oocytes for these parameters.
Rosenbusch
B
B
Department of Gynecology and Obstetrics, University of Ulm, Germany.
Djalali
M
M
Sterzik
K
K
D001826:Body Fluids / Q000378:metabolism*; D003582:Cytogenetics; D005260:Female; D005306:Fertilization; D005307:Fertilization in Vitro; D006728:Hormones / Q000378:metabolism*; D006801:Humans; D009865:Oocytes / Q000502:physiology*; D009994:Osmolar Concentration; D006080:Ovarian Follicle / Q000378:metabolism*
D006728:Hormones