title: Examinations of the relative fluidity in cerebrovascular disease patients.
abstract: Parallel with the increasing incidence of cerebrovascular diseases, and the limitations of possible surgical methods, the importance of drug therapy has significantly increased. Due to our knowledge of haemorheology the effectiveness of therapies may be measured by means of useful circulatory markers. In course of our research activities of one and a half decades the changes in blood viscosity were measured during vinpocetine therapy, and were compared to the changes of haematocrit and mean corpuscular volume (MCV) values. The effect of vinpocetine and secale alkaloids or vinpocetine and pentoxifylline were compared by sequential analysis in other cases. The results of these examinations proved that vinpocetine is effective in both short and long-term therapy.
authors.affiliation: Department of Neurology, Municipal Jahn Ferenc Hospital, Budapest.
authors.forename: A
authors.initials: A
authors.lastname: Szobor
authors.forename: M
authors.initials: M
authors.lastname: Klein
mesh_terms: D000328:Adult; D001809:Blood Viscosity / Q000187:drug effects*; D002561:Cerebrovascular Disorders / Q000097:blood* / Q000188:drug therapy; D004876:Ergot Alkaloids / Q000494:pharmacology / Q000627:therapeutic use; D004909:Erythrocyte Indices; D005260:Female; D006400:Hematocrit; D006801:Humans; D008297:Male; D008875:Middle Aged; D010431:Pentoxifylline / Q000494:pharmacology / Q000627:therapeutic use; D014665:Vasodilator Agents / Q000494:pharmacology / Q000627:therapeutic use; D014748:Vinca Alkaloids / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D004876:Ergot Alkaloids; D014665:Vasodilator Agents; D014748:Vinca Alkaloids; C013983:vinpocetine; D010431:Pentoxifylline