title: Estimation of the male and female mutation rates in Duchenne muscular dystrophy (DMD).
abstract: We present the results of an international collaborative study aimed at estimating the ratio of male to female mutation rates in Duchenne muscular dystrophy based on the method of C. Müller and T. Grimm. With a sample size of 295, this ratio is found to be very close to 1, thus giving evidence for equal mutation rates in males and females in Duchenne muscular dystrophy.
authors.affiliation: Abteilung für pädiatrische Genetik und pränatale Diagnostik, Kinderpoliklinik der Universität, München, Federal Republic of Germany.
authors.forename: B
authors.initials: B
authors.lastname: Müller
authors.forename: C
authors.initials: C
authors.lastname: Dechant
authors.forename: G
authors.initials: G
authors.lastname: Meng
authors.forename: S
authors.initials: S
authors.lastname: Liechti-Gallati
authors.forename: R A
authors.initials: RA
authors.lastname: Doherty
authors.forename: J F
authors.initials: JF
authors.lastname: Hejtmancik
authors.forename: E
authors.initials: E
authors.lastname: Bakker
authors.forename: A P
authors.initials: AP
authors.lastname: Read
authors.forename: M
authors.initials: M
authors.lastname: Jeanpierre
authors.forename: K H
authors.initials: KH
authors.lastname: Fischbeck
mesh_terms: D015139:Blotting, Southern; D005060:Europe; D005260:Female; D006801:Humans; D008297:Male; D008433:Mathematics; D009136:Muscular Dystrophies / Q000235:genetics*; D009154:Mutation / Q000235:genetics; D012737:Sex Factors; D014481:United States