title: Mutagenicity of organic emissions from unvented kerosene heaters in a chamber study.
abstract: A study was conducted to assess the mutagenicity of semivolatile organics and particle-bound organics emitted from unvented kerosene space heaters. The units tested included a well-tuned radiant heater and a maltuned convective heater. The tests were conducted in a 27-m3 chamber with a prescribed on/off heater usage pattern. The organic emissions were collected on Teflon-coated glass filters backed by XAD-2 resin. The dichloromethane-extractable organics from both the filters and the XAD were analyzed for nitropolycyclic hydrocarbons using gas chromatography/mass spectrometry, and were bioassayed for mutagenicity in microsuspension assays using Salmonella typhimurium strains TA98 with and without S9 and TA98NR (a nitroreductase-deficient strain) without S9. The results showed that both the semivolatile and particle-bound organics emitted from the kerosene heaters were mutagenic, and the presence of nitropolycyclic hydrocarbons in these organic emissions substantiated these findings.
authors.affiliation: U.S. Environmental Protection Agency, Research Triangle Park, NC 27711.
authors.forename: J L
authors.initials: JL
authors.lastname: Mumford
authors.forename: J
authors.initials: J
authors.lastname: Lewtas
authors.forename: K
authors.initials: K
authors.lastname: Williams
authors.forename: W G
authors.initials: WG
authors.lastname: Tucker
authors.forename: G W
authors.initials: GW
authors.lastname: Traynor
mesh_terms: D000393:Air Pollutants / Q000032:analysis* / Q000633:toxicity; D001273:Atmosphere Exposure Chambers; D007648:Kerosene / Q000633:toxicity*; D009152:Mutagenicity Tests; D009153:Mutagens / Q000633:toxicity*
chemical_list: D000393:Air Pollutants; D007648:Kerosene; D009153:Mutagens