[The incorporation of acyclovir into the treatment of peripheral paralysis. A study of 45 cases].
The relation between use of acyclovir and facial nerve palsy prognosis was studied. In a randomised study, steroids or steroids + acyclovir (oral doses for Bell's palsy, and intravenous doses for Ramsay Hunt's syndrome) were given to 45 patients with facial palsy. There was a significant reduction of sequelae in patients treated with acyclovir in the group of Ramsay Hunt's syndrome (n = 15) (p less than 0.05). There were no significant differences in the group of Bell's palsy (n = 30) (p greater than 0.05), treated with acyclovir compared with steroids.
Ramos Macías
A
A
Servicio de ORL, Hospital Clínico Universitario de Salamanca.
de Miguel Martínez
I
I
Martín Sánchez
A M
AM
Gómez González
J L
JL
Martín Galán
A
A
D000212:Acyclovir / Q000627:therapeutic use*; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005158:Facial Paralysis / Q000175:diagnosis / Q000188:drug therapy*; D016697:Herpes Zoster Oticus / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D011379:Prognosis
D000305:Adrenal Cortex Hormones; D000212:Acyclovir
Incorporación del aciclovir en el tratamiento de la parálisis periférica. Un estudio en 45 casos.