title: Middle ear disease in cleft palate children at three years of age.
abstract: Fourty-four cleft palate children consecutively referred to a plastic surgery unit were treated with palate repair at one year of age by one surgeon. The children were not routinely treated with ventilating tubes for middle ear disease. At 3 years of age they were investigated for aural pathology. Also specific antipneumococcal antibody activity was measured and was found to be compatible with the activity found in healthy age-matched control children. In the cleft palate children with no immaturity of the immune system only a slight increase in frequency of acute otitis media was evident. One third of the children had however suffered from long-standing secretory otitis media which can be regarded to be more common than what has been found in the normal population in several epidemiologic studies. At 3-4 years of age 82% of the children had a normal hearing indicating an improvement of the condition.
authors.affiliation: Department of Otorhinolaryngology, Huddinge University Hospital, Sweden.
authors.forename: B
authors.initials: B
authors.lastname: Rynnel-Dagöö
authors.forename: K
authors.initials: K
authors.lastname: Lindberg
authors.forename: D
authors.initials: D
authors.lastname: Bagger-Sjöbäck
authors.forename: O
authors.initials: O
authors.lastname: Larson
mesh_terms: D000208:Acute Disease; D000907:Antibodies, Bacterial / Q000032:analysis; D002675:Child, Preschool; D002972:Cleft Palate / Q000150:complications* / Q000276:immunology / Q000601:surgery; D005260:Female; D034381:Hearing Loss / Q000209:etiology; D006312:Hearing Loss, Bilateral / Q000209:etiology; D006801:Humans; D008297:Male; D010033:Otitis Media / Q000150:complications* / Q000276:immunology; D010034:Otitis Media with Effusion / Q000150:complications; D013296:Streptococcus pneumoniae / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial