title: Valve replacement in octogenarians: increased early mortality but good long-term result.
abstract: Between January 1983 and December 1990, 20 patients aged 80 years or older underwent valvular surgery. The patients' ages varied from 80 to 87 years (mean, 82 +/- 1.5 years). The indication for operation was aortic stenosis in 19 patients, and mitral insufficiency after previous mitral valve replacement with a bioprosthesis in one. There were 15 elective, two urgent, and three emergency operations. Four of these patients had aortic valve replacement plus coronary artery bypass grafting. Six patients (30%) had an uneventful hospital stay, and the other 14 (70%) experienced several post-operative complications. The operative mortality rate was 15% (three patients). All patients before operation were in NYHA (New York Heart Association) class III and IV and all survivors remained in NYHA class I or II. The survivors have been followed from 6 to 70 months (mean 20 +/- 8 months). The actuarial survival rate at 1 and 5 years was 78.5% and 67%, respectively. Valvular replacement in octogenarians can be performed, despite the high rate of post-operative complications, with increased but acceptable mortality. Long-term results are good.
authors.affiliation: Clinic for Cardiovascular Surgery, University Hospital Zurich, Switzerland.
authors.forename: M
authors.initials: M
authors.lastname: Pasic
authors.forename: T
authors.initials: T
authors.lastname: Carrel
authors.forename: A
authors.initials: A
authors.lastname: Laske
authors.forename: E
authors.initials: E
authors.lastname: Bauer
authors.forename: J
authors.initials: J
authors.lastname: Turina
authors.forename: R
authors.initials: R
authors.lastname: Jenni
authors.forename: L
authors.initials: L
authors.lastname: von Segesser
authors.forename: M
authors.initials: M
authors.lastname: Turina
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001021:Aortic Valve / Q000601:surgery*; D001705:Bioprosthesis; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000601:surgery*; D011183:Postoperative Complications / Q000401:mortality*; D011474:Prosthesis Design; D015996:Survival Rate