Lupus nephritis: prognostic factors and probability of maintaining life-supporting renal function 10 years after the diagnosis. Gruppo Italiano per lo Studio della Nefrite Lupica (GISNEL).
Data from 659 patients with a diagnosis of lupus nephritis were retrospectively collected among 32 nephrology centers in Italy, as a result of the collaborative effort of the Gruppo Italiano per lo Studio della Nefrite Lupica (GISNEL, Italian Lupus Nephritis Study Group). The overall probability of renal survival was 80% 10 years after the diagnosis. The probability of maintaining life-supporting renal function was evaluated according to several variables (clinical characteristics at presentation, World Health Organization [WHO] histologic classification). The presence at the time of diagnosis of hypertension and diffuse proliferative nephritis (WHO class IV) was associated with a worse prognosis.
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003404:Creatinine / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000150:complications; D007668:Kidney / Q000473:pathology / Q000503:physiopathology*; D007676:Kidney Failure, Chronic / Q000453:epidemiology* / Q000209:etiology; D008181:Lupus Nephritis / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011507:Proteinuria / Q000209:etiology; D012189:Retrospective Studies; D012307:Risk Factors; D016019:Survival Analysis; D013997:Time Factors
D003404:Creatinine