Intestinal absorption of inorganic mercury in rat.
203Hg-Mercuric chloride was administered intragastrically to female rats. The absorption rate evaluated for a broad range of doses was found constant for low and medium range, and higher for high doses. Mercury was determined in internal organs and intestines. The time-course of intestinal mercury indicated that a deposit formed initially in the mucosa was further absorbed into the circulation. No indication was found of a protection mechanism based on exfoliation of the mucosal deposits of metal.
Piotrowski
J K
JK
Department of Toxicological Chemistry, Medical Academy, Lódź, Poland.
Szymańska
J A
JA
Skrzypińska-Gawrysiak
M
M
Kotelo
J
J
Sporny
S
S
D000818:Animals; D005260:Female; D007408:Intestinal Absorption; D008627:Mercuric Chloride / Q000008:administration & dosage / Q000493:pharmacokinetics*; D008631:Mercury Radioisotopes; D051381:Rats; D011919:Rats, Inbred Strains
D008631:Mercury Radioisotopes; D008627:Mercuric Chloride