title: Immunohistochemical characterization of experimental Greene melanoma.
abstract: 20 experimental amelanotic Greene melanomas implanted into the anterior chamber of rabbit eyes were examined immunohistochemically in paraffin sections. All the Greene melanomas were found to be positive for vimentin, S-100 and HMB 45 and negative for alpha-human chorionic gonadotropin, neuron-specific enolase, chromogranin, synaptophysin, cytokeratin, carcino-embryonic antigen, serotonin, desmin and pan leukocyte marker T-200. Greene melanoma is comparable with human cutaneous and uveal melanoma in its immunohistochemical reaction pattern.
authors.affiliation: Department of Pathology, University of Freiburg, FRG.
authors.forename: G
authors.initials: G
authors.lastname: Wollensak
mesh_terms: D000818:Animals; D000867:Anterior Chamber; D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm / Q000032:analysis; D004195:Disease Models, Animal; D005134:Eye Neoplasms / Q000276:immunology / Q000378:metabolism*; D005260:Female; D007124:Immunoenzyme Techniques; D008545:Melanoma / Q000276:immunology / Q000378:metabolism*; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins / Q000032:analysis*; D011817:Rabbits; D009418:S100 Proteins / Q000032:analysis*; D014746:Vimentin / Q000032:analysis*
chemical_list: D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D058950:Melanoma-Specific Antigens; D009363:Neoplasm Proteins; D009418:S100 Proteins; D014746:Vimentin