The paradoxical effects of dietary fish oil on blood pressure.
Dietary fish oil supplementation has received considerable interest as a non-pharmacological adjuvant in the treatment of several diseases, especially hypertension. However, epidemiological, clinical, and experimental evidence conflict. A hypothesis is proposed that fish oil, may have a variable effect on vascular reactivity and consequently, blood pressure. A mechanism is proposed and reasons for the variation in the literature suggested. On the basis of this analysis a potentially adverse effect of dietary fish oil on blood pressure in some individuals is suggested.
Kenny
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Blood Center of Southeastern Wisconsin, Milwaukee 53233-2194.
D000818:Animals; D002561:Cerebrovascular Disorders / Q000209:etiology; D004042:Dietary Fats, Unsaturated / Q000009:adverse effects*; D005395:Fish Oils / Q000009:adverse effects*; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D008954:Models, Biological
D004042:Dietary Fats, Unsaturated; D005395:Fish Oils