title: The use of hepatobiliary scintigraphy in patients with acalculous biliary colic.
abstract: Twelve patients with biliary colic had no evidence of gallstones but underwent cholecystokinin-augmented hepatobiliary scintigraphy that revealed gallbladder ejection fractions of less than 35%. All 12 patients underwent cholecystectomy. Biliary colic was relieved in all patients at a mean postoperative follow-up of 2.5 years. The biliary colic in these patients was probably caused by abnormal gallbladder emptying, itself apparently produced by either cystic duct obstruction or abnormal motility. Biliary abnormality was seen at operation in most patients, and all patients had abnormalities of the gallbladder or cystic duct seen grossly or histologically. These abnormalities included cystic duct stenosis or adhesions, chronic inflammation, and cholesterolosis.
authors.affiliation: Department of Surgery, State University of New York, Syracuse 13210.
authors.forename: J D
authors.initials: JD
authors.lastname: Halverson
authors.forename: B A
authors.initials: BA
authors.lastname: Garner
authors.forename: B A
authors.initials: BA
authors.lastname: Siegel
authors.forename: R
authors.initials: R
authors.lastname: Alexander
authors.forename: S A
authors.initials: SA
authors.lastname: Edmundowicz
authors.forename: W
authors.initials: W
authors.lastname: Campbell
authors.forename: J E
authors.initials: JE
authors.lastname: Miller
mesh_terms: D000328:Adult; D000368:Aged; D000814:Aniline Compounds; D001660:Biliary Tract Diseases / Q000000981:diagnostic imaging* / Q000601:surgery; D002763:Cholecystectomy; D003085:Colic / Q000000981:diagnostic imaging* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D005704:Gallbladder / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D005998:Glycine; D006801:Humans; D007098:Imino Acids; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D012844:Sincalide; D019785:Technetium Tc 99m Disofenin
chemical_list: D000814:Aniline Compounds; D007098:Imino Acids; D015609:Organotechnetium Compounds; C034837:technetium Tc 99m mebrofenin; D012844:Sincalide; D019785:Technetium Tc 99m Disofenin; D005998:Glycine