[Determination of Toxoplasma IgM by ELISA in maternal blood and cord blood of infants born with abnormalities or fetal death].
In this study, Toxoplasma IgM antibodies in serum samples of 54 women who had maternal problems like abortion, preterm, fetal exitus, delivery with pediatric anomalies have been investigated with ELISA. In the cord sera of babies of these mothers, Toxo-IgM has been investigated too. Six mothers have been found to be Toxo-IgM seropositivity (11.11%). Toxo-IgM has been found negative in all of the cord samples. Three of Toxo-IgM positive mothers had fetal exitus and one of them had intrauterine growth retardation. One pregnancy has been terminated as abortion, the other as newborn with multiple anomalies. We have found out that active, latent or reactive toxoplasmosis have to be discriminated and for this purpose detection of Toxo-IgM levels is useful.
Cengiz
A T
AT
Tip Fakültesi Mikrobiyoloji Ana Bilim Dali.
Kiyan
M
M
Cengiz
L
L
Kara
F
F
Uğurel
M S
MS
D000022:Abortion, Spontaneous / Q000209:etiology; D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D000013:Congenital Abnormalities / Q000209:etiology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005312:Fetal Blood / Q000276:immunology; D005313:Fetal Death / Q000209:etiology*; D005317:Fetal Growth Retardation / Q000209:etiology; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood*; D007231:Infant, Newborn; D007752:Obstetric Labor, Premature / Q000209:etiology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000150:complications
D000913:Antibodies, Protozoan; D007075:Immunoglobulin M
Olü veya anomalili bebek doğumu yapan anne serumlarinda ve bebeklerin kordon serumlarinda, elisa ile toksoplazma IgM'nin araştirilmasi.