title: Comparison of whole saliva flow rates and mucin concentrations in healthy Caucasian young and aged adults.
abstract: Unstimulated and chewing-stimulated whole saliva samples were obtained from 42 healthy Caucasians; 21 were between 18 and 35 years of age, and 21 between 65 and 83 years of age. The unstimulated salivary flow rate was significantly lower in the aged group, but the stimulated flow rate was significantly higher in the aged than in the young group. Both groups showed significantly increased flow during salivary stimulation. MG1 and MG2 concentrations in unstimulated and stimulated saliva samples were significantly lower in the aged group. There were no significant correlations between salivary flow rates and MG1 and MG2 concentrations.
authors.affiliation: Department of Dental Medicine and Public Health, School of Dentistry, University of Southern California, Los Angeles 90089-0641.
authors.forename: M
authors.initials: M
authors.lastname: Navazesh
authors.forename: R A
authors.initials: RA
authors.lastname: Mulligan
authors.forename: V
authors.initials: V
authors.lastname: Kipnis
authors.forename: P A
authors.initials: PA
authors.lastname: Denny
authors.forename: P C
authors.initials: PC
authors.lastname: Denny
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D000704:Analysis of Variance; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008409:Mastication; D009077:Mucins / Q000032:analysis*; D012463:Saliva / Q000737:chemistry* / Q000378:metabolism*; D012636:Secretory Rate
chemical_list: D009077:Mucins