Low-dose tamoxifen retinopathy.
A 68-year-old woman with metastatic breast carcinoma manifested bilateral tamoxifen-induced retinopathy after 9 years of low-dose therapy. Treatment with the drug was stopped, with partial resolution of the retinopathy and improvement in visual acuity over 2 1/2 years of follow-up.
Chang
T
T
Ivey Institute of Ophthalmology, Victoria Hospital, London, On.
Gonder
J R
JR
Ventresca
M R
MR
D000368:Aged; D001943:Breast Neoplasms / Q000188:drug therapy / Q000601:surgery; D002277:Carcinoma / Q000188:drug therapy / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D015409:Mastectomy, Radical; D012164:Retinal Diseases / Q000139:chemically induced*; D013629:Tamoxifen / Q000009:adverse effects* / Q000627:therapeutic use; D014792:Visual Acuity
D013629:Tamoxifen