Site-specific mutations of nicotinic acetylcholine receptor at the lipid-protein interface dramatically alter ion channel gating.
Li
L
L
Department of Biochemistry and Biophysics, University of California, Davis 95616.
Lee
Y H
YH
Pappone
P
P
Palma
A
A
McNamee
M G
MG
D000818:Animals; D055592:Biophysical Phenomena; D001703:Biophysics; D003001:Cloning, Molecular; D005260:Female; D015640:Ion Channel Gating / Q000235:genetics* / Q000502:physiology; D008563:Membrane Lipids / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D016297:Mutagenesis, Site-Directed; D009865:Oocytes / Q000378:metabolism; D011978:Receptors, Nicotinic / Q000235:genetics* / Q000378:metabolism; D014101:Torpedo; D014981:Xenopus
D008563:Membrane Lipids; D008565:Membrane Proteins; D011978:Receptors, Nicotinic