Localized scleroderma and hemiatrophy in association with antibodies to double-stranded DNA.
Localized scleroderma involves primarily skin but also muscle, bone and synovium. Further associations and transitional forms have been reported. We report here two cases showing associations between localized scleroderma and vasculitis, mononeuritis multiplex, juvenile chronic arthritis and hemiatrophy. In particular our cases both possess antibodies to double-stranded DNA, a finding not previously reported.
Adebajo
A O
AO
Department of Rheumatology, Addenbrooke's Hospital, Cambridge, UK.
Crisp
A J
AJ
Nicholls
A
A
Hazleman
B L
BL
D000293:Adolescent; D000974:Antibodies, Antinuclear / Q000032:analysis*; D001171:Arthritis, Juvenile / Q000276:immunology*; D005146:Facial Asymmetry / Q000276:immunology*; D005260:Female; D016523:Foot Ulcer / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012594:Scleroderma, Localized / Q000276:immunology*
D000974:Antibodies, Antinuclear