title: Sample size requirements for stratified cluster randomization designs.
abstract: Sample size requirements are provided for designs of studies in which clusters are randomized within each of several strata, where cluster size itself may be a stratifying factor. The approach generalizes a formula derived by Woolson et al., which provides sample size requirements for the Cochran-Mantel-Haenszel statistic. Issues of data analysis are also discussed.
authors.affiliation: Department of Epidemiology and Biostatistics, University of Western Ontario, London, Canada.
authors.forename: A
authors.initials: A
authors.lastname: Donner
mesh_terms: D016000:Cluster Analysis; D006801:Humans; D016555:Matched-Pair Analysis; D016016:Proportional Hazards Models; D016032:Randomized Controlled Trials as Topic / Q000592:standards*; D012107:Research Design / Q000592:standards*; D012494:Sampling Studies