[Morphometric evidence of activation of axo-somatic synapses during administration of delta sleep-inducing peptide].
Computed morphometry proved activation of neocortex layer III-V axosomatic synapses. This is evident from an increase in the mean plasmalemma length, that in the active synapse zones on neurone bodies and width of the synaptic cleft, this being induced by a single intraperitoneal administration of delta-sleep-inducing peptide. The activation of the axosomatic synapses correlates with elevated GABA levels in the cerebral hemispheres cortex.
Mendzheritskiĭ
A M
AM
Kuraev
G A
GA
Mikhaleva
I I
II
Povilaĭtite
P E
PE
D000818:Animals; D003701:Delta Sleep-Inducing Peptide / Q000494:pharmacology*; D009044:Motor Cortex / Q000187:drug effects; D051381:Rats; D013569:Synapses / Q000187:drug effects* / Q000648:ultrastructure; D013997:Time Factors
D003701:Delta Sleep-Inducing Peptide
Morfometricheskie dokazatel'stva aktivatsii akso-somaticheskikh sinapsov pri vvedenii del'ta-son indutsiruiushchego peptida.