title: Molecular and classical cytogenetic analyses demonstrate an apomorphic reciprocal chromosomal translocation in Gorilla gorilla.
abstract: The existence of an apomorphic reciprocal chromosomal translocation in the gorilla lineage has been asserted or denied by various cytogeneticists. We employed a new molecular cytogenetic strategy (chromosomal in situ suppression hybridization) combined with high-resolution banding, replication sequence analysis, and fluorochrome staining to demonstrate that a reciprocal translocation between ancestral chromosomes homologous to human chromosome 5 and 17 has indeed occurred.
authors.affiliation: Istituto di Antropologia fisica, University of Genoa, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Stanyon
authors.forename: J
authors.initials: J
authors.lastname: Wienberg
authors.forename: D
authors.initials: D
authors.lastname: Romagno
authors.forename: F
authors.initials: F
authors.lastname: Bigoni
authors.forename: A
authors.initials: A
authors.lastname: Jauch
authors.forename: T
authors.initials: T
authors.lastname: Cremer
mesh_terms: D000818:Animals; D002871:Chromosome Banding; D002886:Chromosomes, Human, Pair 17; D002895:Chromosomes, Human, Pair 5; D015342:DNA Probes; D004261:DNA Replication; D015723:Gene Library; D006071:Gorilla gorilla / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D008251:Macaca / Q000235:genetics; D009693:Nucleic Acid Hybridization; D002679:Pan troglodytes / Q000235:genetics; D010957:Plasmids; D014178:Translocation, Genetic
chemical_list: D015342:DNA Probes