title: The staggerer gene curtails the reproductive life span of females.
abstract: Three studies were undertaken to investigate some features of the reproductive activity of female staggerer mice of the C57BL/6 strain. It was found that in the staggerer female, (1) vaginal opening and onset of vaginal estrous cycling were delayed; (2) the vaginal estrous cycle was irregular and characterized by abnormally prolonged diestrous and estrous phases, and (3) the reproductive life span of the mutant female was confined to a 3-month period after puberty. The abnormalities observed in sexual functions suggest a specific influence of the staggerer gene on reproductive activity.
authors.affiliation: Laboratoire d'Ethologie et Sociobiologie, URA CNRS No 667, Université Paris XIII, Villetaneuse, France.
authors.forename: J M
authors.initials: JM
authors.lastname: Guastavino
authors.forename: K
authors.initials: K
authors.lastname: Larsson
mesh_terms: D000818:Animals; D004971:Estrus / Q000235:genetics*; D005260:Female; D051379:Mice; D008818:Mice, Neurologic Mutants / Q000235:genetics*; D010641:Phenotype; D012726:Sexual Behavior, Animal; D012741:Sexual Maturation / Q000235:genetics*