Serum antibodies to Chlamydia trachomatis in women with ectopic pregnancy, normal pregnancy or salpingitis.
Serum antichlamydial antibodies were studied in three groups. Group A included 49 women with recent ectopic pregnancy, group B included 56 women with normal first trimester pregnancy, and group C included 20 women with a first episode of acute salpingitis. In the ectopic pregnancy group, a significantly higher percentage of women had IgG antichlamydial antibodies than in the normal pregnancy group (75.5% vs. 46.4%, P less than 0.001). Women with acute salpingitis had the same prevalence of IgG antibodies as patients who had an ectopic pregnancy (60% vs. 75.5%, P less than 0.10). In the ectopic pregnancy group, the women had a significantly higher geometric mean titer (GMT) of antichlamydial IgG antibodies than women with an intra-uterine pregnancy (70.4% vs. 27.3%, P less than 0.001). The results suggest that there is a positive relation between prior Chlamydia trachomatis infection and risk for tubal pregnancy.
Chrysostomou
M
M
Department of Gynaecology, General Hospital of Athens, Greece.
Karafyllidi
P
P
Papadimitriou
V
V
Bassiotou
V
V
Mayakos
G
G
D000208:Acute Disease; D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood*; D002692:Chlamydia trachomatis / Q000276:immunology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D011247:Pregnancy / Q000276:immunology*; D011274:Pregnancy, Tubal / Q000276:immunology* / Q000382:microbiology; D012307:Risk Factors; D012488:Salpingitis / Q000276:immunology* / Q000382:microbiology
D000907:Antibodies, Bacterial; D007074:Immunoglobulin G