title: Variations between Biomer lots. I. Significant differences in the surface chemistry of two lots of a commercial poly(ether urethane).
abstract: We have studied the surface chemistry of two lots of Biomer (BSP067 and BSUA001), a widely used commercial poly(ether urethane) (PEU). Although transmission infrared adsorption studies revealed no differences in the bulk chemistry of the two lots, the surface chemistry, as seen by x-ray photoelectron spectroscopy (XPS) and static secondary ion mass spectrometry (SIMS), was different. Lot BSP067 showed soft-segment enrichment at the surface, which is typical of PEU. Lot BSUA001 showed no evidence of either hard- or soft-segment PEU components at the surface. The surface of this lot was completely covered with a nonextractable additive identified as poly(diisopropyl amino ethyl methacrylate). Small amounts of a low-molecular-weight antioxidant were observed at the surface of both samples. Because the biological response to polymers is dependent on surface structure, these results are of considerable importance to biomaterials research.
authors.affiliation: Department of Chemical Engineering, University of Washington, Seattle 98195.
authors.forename: B J
authors.initials: BJ
authors.lastname: Tyler
authors.forename: B D
authors.initials: BD
authors.lastname: Ratner
authors.forename: D G
authors.initials: DG
authors.lastname: Castner
authors.forename: D
authors.initials: D
authors.lastname: Briggs
mesh_terms: D000975:Antioxidants; D001672:Biocompatible Materials; D002850:Chromatography, Gel; D004577:Electron Probe Microanalysis; D015394:Molecular Structure; D011140:Polyurethanes / Q000737:chemistry* / Q000592:standards; D013055:Spectrophotometry, Infrared; D013499:Surface Properties
chemical_list: D000975:Antioxidants; D001672:Biocompatible Materials; D011140:Polyurethanes; C031892:biomer