title: Exogenous ochronosis.
abstract: Exogenous ochronosis is a condition characterized by hyperpigmentation of the face secondary to the use of hydroquinone-containing bleaching creams. Histopathologically, it presents a collection of yellowish-brown (ochronotic) globules in the papillary dermis. Two cases of exogenous ochronosis are reported, followed by a review of the literature.
authors.affiliation: Department of Dermatology, School of Medicine, University of Puerto Rico.
authors.forename: R F
authors.initials: RF
authors.lastname: Martín
authors.forename: J L
authors.initials: JL
authors.lastname: Sánchez
authors.forename: A
authors.initials: A
authors.lastname: González
authors.forename: A
authors.initials: A
authors.lastname: Lugo-Somolinos
authors.forename: H
authors.initials: H
authors.lastname: Ruiz
mesh_terms: D000328:Adult; D003358:Cosmetics / Q000009:adverse effects; D003879:Dermatologic Agents / Q000009:adverse effects; D005260:Female; D006801:Humans; D006873:Hydroquinones / Q000009:adverse effects*; D008875:Middle Aged; D009794:Ochronosis / Q000139:chemically induced* / Q000473:pathology; D012867:Skin / Q000648:ultrastructure
chemical_list: D003358:Cosmetics; D003879:Dermatologic Agents; D006873:Hydroquinones