Acute myocardial infarction associated with intravenous injection of pentazocine and tripelennamine.
This case report describes the evolution of an acute anteroseptal myocardial infarction in a 27-year-old man following intravenous injection of pentazocine and tripelennamine. Subsequent coronary angiography showed normal coronary arteries. Based on the known mechanism of action of these drugs, it is postulated that myocardial infarction resulted from coronary artery spasm secondary to excessive catecholamine stimulation.
McGwier
B W
BW
Division of Cardiology, University of South Alabama College of Medicine, Mobile.
Alpert
M A
MA
Panayiotou
H
H
Lambert
C R
CR
D000328:Adult; D006328:Cardiac Catheterization; D017023:Coronary Angiography; D004562:Electrocardiography / Q000187:drug effects; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000139:chemically induced* / Q000175:diagnosis; D010423:Pentazocine / Q000008:administration & dosage; D015819:Substance Abuse, Intravenous / Q000150:complications* / Q000175:diagnosis; D014309:Tripelennamine / Q000008:administration & dosage
D014309:Tripelennamine; D010423:Pentazocine