Primary cutaneous large-cell anaplastic (Ki-1) lymphoma in a child.
During a 2-week period, a 9-year-old girl developed a tender, dark red, centrally ulcerated 3 cm tumor on her left thigh, associated with inguinal lymphadenopathy. Histologic and immunohistopathologic evaluation disclosed a Ki-1+ large-cell anaplastic lymphoma. The patient received multiagent chemotherapy followed by autologous bone marrow transplantation and is in her second remission.
Meier
F
F
Department of Dermatology, Eberhard-Karls-Universität, Tübingen, Germany.
Schaumburg-Lever
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G
Kaiserling
E
E
Scheel-Walter
H G
HG
Scherwitz
C
C
D000911:Antibodies, Monoclonal / Q000276:immunology; D000951:Antigens, Neoplasm / Q000032:analysis / Q000276:immunology; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000276:immunology / Q000627:therapeutic use; D016026:Bone Marrow Transplantation; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000276:immunology / Q000628:therapy / Q000648:ultrastructure*; D008854:Microscopy, Electron; D009367:Neoplasm Staging; D012867:Skin / Q000276:immunology / Q000648:ultrastructure*; D012878:Skin Neoplasms / Q000276:immunology / Q000628:therapy / Q000648:ultrastructure*
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm