title: Pressure wave cardiography; cardiac diagnosis by means of noninvasive continuous blood pressure record.
abstract: The pulse pressure (PP) is proportional to the preceding interval (T) because of the restitution of contractility and the Starling mechanism, and is inversely proportional to the pre-preceding interval (T-1) because of potentiation of contractility. The aim of the present paper was to find if this relationship can be used for diagnostic purposes. Blood pressure was noninvasively and continuously recorded for 3 minutes (Penáz method), in 26 healthy subjects, in 13 patients with congestive heart failure (NYHA I,II) and sinusoidal rhythms and in 21 patients with atrial fibrillations. By means of multidimensional regression analysis the coefficient D[T] and D[T-1] were calculated in each subject. D[T] expresses the relative role of the preceding, D[T-1] of the pre-preceding interval. The correlation between PP and T was small in subjects with sinusoidal rhythms. Subjects with particular correlation coefficients between PP and T-1 higher than 0.5 were used for further analysis (18 controls, 7 patients). The difference between D[T-1] in controls (0.30 +/- 0.20) and in patients (0.48 +/- 0.19) was significant (Wilcoxon P less than 0.05). In subjects with atrial fibrillations both D[T] and D[T-1] were higher in decompensated patients (Wilcoxon P less than 0.05). The ratio D[T]/D[T-1] was higher in patients with mitral stenosis than in patients with ischaemic heart disease (t-test, P less than 0.05). The test can be usefully employed as a screening test in medical practice.
authors.affiliation: Department of Physiology, Medical Faculty, Masaryk University, Brno.
authors.forename: B
authors.initials: B
authors.lastname: Fiser
authors.forename: N
authors.initials: N
authors.lastname: Honzíková
authors.forename: B
authors.initials: B
authors.lastname: Semrád
mesh_terms: D001281:Atrial Fibrillation / Q000503:physiopathology; D001795:Blood Pressure Determination / Q000379:methods*; D003327:Coronary Disease / Q000503:physiopathology; D006321:Heart / Q000502:physiology / Q000503:physiopathology*; D006331:Heart Diseases / Q000503:physiopathology*; D006333:Heart Failure / Q000503:physiopathology; D006801:Humans; D008946:Mitral Valve Stenosis / Q000503:physiopathology; D012044:Regression Analysis