title: Late onset familial Hallervorden-Spatz disease: MR findings in two sisters.
abstract: Two sisters affected by late onset Hallervorden-Spatz disease are described. In both patients, MR showed rings of decreased signal intensity surrounding hyperintense areas that gave a target-like appearance to the globi pallidi, a finding that corresponds with the known pathologic lesions in the disease. MR reflects the metabolic and anatomic evaluation of this disease.
authors.affiliation: Department of Neuroradiology, Medical School, University of Bologna, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Ambrosetto
authors.forename: R
authors.initials: R
authors.lastname: Nonni
authors.forename: A
authors.initials: A
authors.lastname: Bacci
authors.forename: G
authors.initials: G
authors.lastname: Gobbi
mesh_terms: D005260:Female; D005917:Globus Pallidus / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D006211:Pantothenate Kinase-Associated Neurodegeneration / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology