title: Chondrosarcomas of the skull base: MR imaging features.
abstract: The magnetic resonance (MR) images from 17 patients with chondrosarcomas of the skull base were retrospectively reviewed to characterize the size, location, signal intensity, and extension of these tumors. Eleven patients with chondrosarcomas received intravenously administered gadopentetate dimeglumine. In 16 patients, computed tomographic (CT) scans were obtained to evaluate intratumorous mineralization and bone erosion. On short repetition time (TR)/echo time (TE) MR images, chondrosarcomas generally had low to intermediate signal intensity; on long TR/TE MR images, they generally had very high signal intensity. Signal heterogeneity on long TR/TE MR images was seen in 10 of 17 tumors (59%) and was caused by matrix mineralization, fibrocartilaginous elements, or both. Matrix mineralization was demonstrated with CT in seven of the 16 chondrosarcomas. Chondrosarcomas showed marked enhancement after administration of gadopentetate dimeglumine in either a heterogeneous (n = 8) or homogeneous (n = 3) pattern. The information about the size and extent of these neoplasms was important in the choice of surgical approaches for gross total resection of tumor.
authors.affiliation: Department of Radiology, University of Pittsburgh School of Medicine, Presbyterian-University Hospital, PA 15213.
authors.forename: S P
authors.initials: SP
authors.lastname: Meyers
authors.forename: W L
authors.initials: WL
authors.lastname: Hirsch
authors.forename: H D
authors.initials: HD
authors.lastname: Curtin
authors.forename: L
authors.initials: L
authors.lastname: Barnes
authors.forename: L N
authors.initials: LN
authors.lastname: Sekhar
authors.forename: C
authors.initials: C
authors.lastname: Sen
mesh_terms: D000328:Adult; D000368:Aged; D002813:Chondrosarcoma / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D012189:Retrospective Studies; D012888:Skull Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed