[Biological and clinical prevalence of pollinosis caused by ragweeds of the upper valley of the Rhône corridor].
An epidemiological study of ragweed allergy was conducted on 646 employees belonging to 6 factories located in the Rhone valley south of the city of Lyon. Information on seasonal evocative clinical symptoms was obtained through a self-administered questionnaire. Biological prevalence was assessed by measuring anti-ragweed IgE specific antibodies. Measurements were performed by immunoenzymatic assay (W1 Phadezym RAST from Pharmacia). 34 (5,4%) subjects had evocative symptoms whereas 37 (5,9%) had increased specific IgE. Persons with the highest IgE levels were symptomatic. Concordance between symptoms and biology was 35% (12/34). Results indicate that sensitization level varies according to the location of the factory and people's residence, the risk to become allergic being of 10% in the most exposed population. This data emphasize the need to promote anti-ragweed eradication policy.
Harf
R
R
Centre hospitalier Lyon Sud Pierre Benite.
Contassot
J C
JC
Dechamp
C
C
Despres
B
B
Deviller
P
P
Diter
P
P
Garcier
Y
Y
Liard
R
R
Neukirch
F
F
Quelin
P
P
D000328:Adult; D005602:France / Q000453:epidemiology; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007221:Industry; D011058:Pollen / Q000276:immunology; D015995:Prevalence; D011852:Radioallergosorbent Test; D006255:Rhinitis, Allergic, Seasonal / Q000453:epidemiology* / Q000209:etiology / Q000276:immunology / Q000517:prevention & control; D012621:Seasons
D007073:Immunoglobulin E
Prévalence biologique et clinique de la pollinose due aux ambroisies dans la vallée supérieure du couloir rhodanien.