The effect of malnutrition on insulin binding to rat erythrocytes.
Insulin binding to erythrocyte receptors was compared in malnourished and control rats. Percentage specific insulin binding to malnourished rat erythrocytes was significantly lower than to control erythrocytes (P less than 0.001). The low insulin binding in the malnourished rat erythrocytes was accompanied by low insulin receptor affinity (P = 0.035).
Payne-Robinson
H M
HM
Tropical Metabolism Research Unit, University of the West Indies, Kingston, Jamaica.
Brown
R
R
D000818:Animals; D004910:Erythrocyte Membrane / Q000378:metabolism; D004912:Erythrocytes / Q000378:metabolism*; D007328:Insulin / Q000378:metabolism*; D009748:Nutrition Disorders / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D011972:Receptor, Insulin / Q000378:metabolism*
D007328:Insulin; D011972:Receptor, Insulin