title: Risk of prophylactic contralateral carotid endarterectomy.
abstract: Fifty-eight patients underwent a prophylactic contralateral carotid endarterectomy following an initial endarterectomy for symptomatic (38 patients) or asymptomatic (20 patients) carotid stenosis. No deaths occurred after either operation. Two (3.4%) minor neurologic deficits occurred after the initial operation and two (3.4%) major and two (3.4%) minor deficits occurred after the prophylactic contralateral carotid endarterectomy. Sixteen (28%) of the initial endarterectomies were associated with perioperative hyper- or hypotensive episodes compared to 35 (60%) of the prophylactic contralateral carotid endarterectomies (p less than 0.001). We did not document an increased risk of surgery in patients undergoing prophylactic contralateral carotid endarterectomy soon after the initial operation. All four neurologic events following a prophylactic contralateral carotid endarterectomy occurred when the operation was performed more than five weeks after the initial endarterectomy. The incidence of perioperative hyper- or hypotension was similar in patients undergoing prophylactic contralateral carotid endarterectomy less than or greater than five weeks after the first operation. Our results suggest that a prophylactic contralateral carotid endarterectomy may be associated with a higher incidence of neurologic complications and hyper- and hypotensive episodes than the initial carotid endarterectomy. Waiting more than five weeks to repair a contralateral asymptomatic carotid stenosis may not enhance the safety of the operation.
authors.affiliation: Section of Vascular Surgery, Pennsylvania Hospital/University of Pennsylvania School of Medicine, Philadelphia.
authors.forename: K D
authors.initials: KD
authors.lastname: Calligaro
authors.forename: B
authors.initials: B
authors.lastname: Hass
authors.forename: C J
authors.initials: CJ
authors.lastname: Westcott
authors.forename: R P
authors.initials: RP
authors.lastname: Savarese
authors.forename: D A
authors.initials: DA
authors.lastname: DeLaurentis
mesh_terms: D000328:Adult; D000368:Aged; D001037:Aphasia / Q000453:epidemiology; D016893:Carotid Stenosis / Q000601:surgery*; D016894:Endarterectomy, Carotid / Q000379:methods; D005260:Female; D006429:Hemiplegia / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D007022:Hypotension / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology*; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome