Involvement of 19q13 in follicular thyroid adenoma.
Cytogenetic investigation of a follicular thyroid adenoma from a 31-year-old woman showed a t(16;19)(q12;q13), as the sole chromosome abnormality. As five more cases with 19q13 involvement have been described, we suggest that the terminal region of the long arm of chromosome 19 is important for the development of follicular thyroid adenoma.
Dal Cin
P
P
Centre for Human Genetics, University of Leuven, Belgium.
Sneyers
W
W
Aly
M S
MS
Segers
A
A
Ostijn
F
F
Van Damme
B
B
Van Den Berghe
H
H
D000236:Adenoma / Q000235:genetics* / Q000473:pathology; D000328:Adult; D002871:Chromosome Banding; D002885:Chromosomes, Human, Pair 16; D002888:Chromosomes, Human, Pair 19; D005260:Female; D006801:Humans; D007621:Karyotyping; D013964:Thyroid Neoplasms / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic