[Modification of radiation sensitivity of lymphocytes of the rat thymus gland using cholesterol-enriched autoliposomes].
The influence of thymocyte enrichment with cholesterol on radiosensitivity of these cells has been studied. The enrichment was performed using autoliposomes. It was found that in the modified cells the processes of lipid peroxidation, enzymatic degradation of chromatin and apoptosis are inhibited.
Posokhov
V S
VS
Rozenberg
O A
OA
Khanson
K P
KP
D000818:Animals; D002784:Cholesterol / Q000008:administration & dosage*; D002843:Chromatin / Q000378:metabolism; D004337:Drug Carriers; D015227:Lipid Peroxidation; D008081:Liposomes; D011838:Radiation-Sensitizing Agents; D051381:Rats; D013601:T-Lymphocytes / Q000187:drug effects / Q000528:radiation effects*
D002843:Chromatin; D004337:Drug Carriers; D008081:Liposomes; D011838:Radiation-Sensitizing Agents; D002784:Cholesterol
Modifikatsiia radiochuvstvitel'nosti limfotsitov timusa krys s pomoshch'iu obogashchennykh kholesterinom autoliposom.