[Is there an unusual incidence of the manifestation of intracranial angiomas in pregnancy? Risk assessment based on 17,733 patients over 10 years].
From 1979-1988, 134 inpatients (m:f = 80:54) were treated because of an intracranial angioma (AVM). The male/female ratio was 3/2 in general as well as during the "reproductive age" (15-45 yrs). In 6 patients (20-27 yrs; grav 2/para 1: n = 3; grav 1/para 0: n = 3) the AVM became symptomatic during pregnancy (n = 4: 23-33 gestational week) or at birth (n = 2). In the group of the presently non-pregnant women (n = 40) 47 uncomplicated deliveries had occurred years before. We conclude that the available data neither allow us to reject nor to confirm the hypothesis that pregnancy and/or delivery influence the manifestation of cerebral AVMs. The reasons for this dilemma of epidemiology are discussed.
Moskopp
D
D
Neurochirurgische Universitätsklinik Westfälischen Wilhelms-Universität Münster.
Janssen
B
B
Schmidt
S
S
Ries
F
F
Krebs
D
D
D000293:Adolescent; D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000453:epidemiology*; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D005858:Germany / Q000453:epidemiology; D006391:Hemangioma / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000453:epidemiology*
Manifestieren sich intrakranielle Angiome im Umfeld einer Schwangerschaft überzufällig häufig? Zum Problem der Risiko- abschätzung anhand von 17,733 Patienten aus 10 Jahren.