title: Adhesive bone cement containing hydroxyapatite particle as bone compatible filler.
abstract: Acrylic bone cement containing hydroxyapatite (HA) as a filler was developed using 4-methacryloyloxyethyl trimellitate anhydride (4-META) to promote adhesion both to bone and HA. The mechanical strengths of the cement did not decrease significantly with increasing HA in the cement by 4-META. However, strengths decreased with increasing HA content in the absence of 4-META. Scanning electron micrographic examination of fractured surfaces of the cement clearly showed that the HA particles adhered to the matrix resin when 4-META was added. Thus, it was important to maintain the original mechanical strengths for 4-META. The HA particles along the surface increased with increased HA content in the cement. The cement adhered to bone with a tensile bond strength was higher than 10 MPa.
authors.affiliation: Institute for Medical and Dental Engineering, Tokyo Medical and Dental University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ishihara
authors.forename: H
authors.initials: H
authors.lastname: Arai
authors.forename: N
authors.initials: N
authors.lastname: Nakabayashi
authors.forename: S
authors.initials: S
authors.lastname: Morita
authors.forename: K
authors.initials: K
authors.lastname: Furuya
mesh_terms: D000180:Acrylic Resins / Q000494:pharmacology*; D000268:Adhesiveness / Q000187:drug effects; D001843:Bone Cements / Q000737:chemistry*; D006882:Hydroxyapatites / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D013718:Tensile Strength / Q000187:drug effects
chemical_list: D000180:Acrylic Resins; D001843:Bone Cements; D006882:Hydroxyapatites; C031172:4-META resin