title: [Bilateral optic neuropathy with papilledema].
abstract: The findings in nine patients are presented who suffered from acute bilateral visual loss occurring within less than one week, and all showed optic disc edema. CT scans revealed no abnormalities and the CSF-pressure measured in 6 patients was normal. Four of the patients (22 to 53 years old) recovered completely under orally given prednisolone (about 100 mg/day). The recent history of three patients suggested that the optic neuropathy was associated with an infection. This parainfectious process may be identical to the bilateral optic neuritis described in children. Four older patients (55 to 63 years) did not respond to steroid therapy. Their vision did not significantly improve. They showed attenuated retinal arteries; therefore it can be assumed that ischemia plays a role in the pathogenesis of this second type of optic neuropathy. In none of the cases a toxic optic neuropathy could be confirmed. One patient who experienced a visual loss down to finger counting after throat-surgery without marked blood loss recovered partially after steroid treatment.
authors.affiliation: Abteilung für Pathophysiologie des Sehens und Neuroophthalmologie, Universitäts-Augenklinik Tübingen.
authors.forename: H
authors.initials: H
authors.lastname: Wilhelm
authors.forename: U
authors.initials: U
authors.lastname: Schiefer
authors.forename: H
authors.initials: H
authors.lastname: Wiethölter
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009902:Optic Neuritis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D010211:Papilledema / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D011241:Prednisone / Q000008:administration & dosage; D014792:Visual Acuity / Q000187:drug effects / Q000502:physiology; D014794:Visual Fields / Q000187:drug effects / Q000502:physiology
chemical_list: D011241:Prednisone
vernacular_title: Bilaterale Optikusneuropathien mit Papillenschwellung.