title: [Preventive treatment of systemic embolic complications of atrial fibrillation].
abstract: Non-valvular atrial fibrillation multiplies the risk of presumed embolic events by a factor of four. The hemorrhagic risk of anticoagulant treatment varies considerably and its prophylactic efficacy was not tested in any randomised trial before the end of 1989. The recommendations of experts at that time recognised that data were inadequate. The publication since of four randomised trials involving 3,049 patients has provided a more objective base for management decisions, highly in favour of the anticoagulation of cases of non-isolated atrial fibrillation in the absence of contraindications.
authors.affiliation: Hôpital Cardiologique, Lille.
authors.forename: P
authors.initials: P
authors.lastname: Asseman
authors.forename: J J
authors.initials: JJ
authors.lastname: Bauchart
authors.forename: N
authors.initials: N
authors.lastname: Amrouni
authors.forename: M
authors.initials: M
authors.lastname: Lesenne
authors.forename: C
authors.initials: C
authors.lastname: Neuville
authors.forename: C
authors.initials: C
authors.lastname: Loubeyre
authors.forename: M
authors.initials: M
authors.lastname: Elkohen
authors.forename: C
authors.initials: C
authors.lastname: Thery
authors.forename: B
authors.initials: B
authors.lastname: Jude
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000150:complications* / Q000503:physiopathology; D004617:Embolism / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D012307:Risk Factors
chemical_list: D000925:Anticoagulants
vernacular_title: Le traitement prophylactique des complications emboliques systémiques de la fibrillation auriculaire.