title: Filtration sizes of human immunodeficiency virus type 1 and surrogate viruses used to test barrier materials.
abstract: Filters with well-defined holes were used to determine the effective diameters in buffer of human immunodeficiency virus type 1, herpes simplex virus type 1, and four bacteriophages (phi X174, T7, PRD1, and phi 6), which may serve as surrogate viruses for testing barrier materials. Bacteriophages phi 6 and PRD1 most closely model human immunodeficiency virus type 1 in filtration size.
authors.affiliation: Food and Drug Administration Center for Devices and Radiological Health, Rockville, Maryland.
authors.forename: C D
authors.initials: CD
authors.lastname: Lytle
authors.forename: S C
authors.initials: SC
authors.lastname: Tondreau
authors.forename: W
authors.initials: W
authors.lastname: Truscott
authors.forename: A P
authors.initials: AP
authors.lastname: Budacz
authors.forename: R K
authors.initials: RK
authors.lastname: Kuester
authors.forename: L
authors.initials: L
authors.lastname: Venegas
authors.forename: R E
authors.initials: RE
authors.lastname: Schmukler
authors.forename: W H
authors.initials: WH
authors.lastname: Cyr
mesh_terms: D000818:Animals; D001435:Bacteriophages / Q000648:ultrastructure*; D005374:Filtration / Q000379:methods*; D015497:HIV-1 / Q000648:ultrastructure*; D006801:Humans