Highly informative dinucleotide repeat polymorphism at the D11S29 locus on chromosome 11q23.
The informativeness of locus D11S29 as a genetic marker was improved by the identification of a highly polymorphic (GT)n repeat within the locus. Ten alleles were identified in parents of 40 Centre d'Etude du Polymorphisme Humain families and the polymorphism information content (PIC) was 0.77. The increased PIC value thus enables refinement of the linkage map of 11q23.
Warnich
L
L
Department of Human Genetics, Tygerberg Hospital, Republic of South Africa.
Groenewald
I
I
Theart
L
L
Retief
A E
AE
D000483:Alleles; D001483:Base Sequence; D002880:Chromosomes, Human, Pair 11; D005260:Female; D005787:Gene Frequency / Q000235:genetics; D008040:Genetic Linkage / Q000235:genetics; D005819:Genetic Markers / Q000235:genetics; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D010375:Pedigree; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic / Q000235:genetics*; D012091:Repetitive Sequences, Nucleic Acid
D005819:Genetic Markers