title: Does Bowman's layer determine the biomechanical properties of the cornea?
abstract: BACKGROUND
  Bowman's layer is believed to be the stabilizing element of corneal curvature due to its assumed mechanical stiffness.
  
  
  METHODS
  Uniaxial stress-strain analysis was performed in paired corneal strips to compare the contribution from Bowman's layer. Two central strips were taken from each cornea and Bowman's layer was removed from one of them with the excimer laser.
  
  
  RESULTS
  Pairwise comparison yielded no statistical difference in elastic or viscoelastic properties according to presence or absence of Bowman's layer. At a strain of 2%, the stress was measured to be (5.06 +/- 2.01) x 10(3) N/m2 with Bowman's layer and (4.72 +/- 1.3) x 10(3) N/m2 without Bowman's layer. Also, the two relaxation times did not differ significantly.
  
  
  CONCLUSIONS
  These findings imply that Bowman's layer does not contribute significantly to mechanical stability within the cornea.
authors.affiliation: Universitäts-Augenklinik im Klinikum Charlottenburg, Freie Universität Berlin, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Seiler
authors.forename: M
authors.initials: M
authors.lastname: Matallana
authors.forename: S
authors.initials: S
authors.lastname: Sendler
authors.forename: T
authors.initials: T
authors.lastname: Bende
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001696:Biomechanical Phenomena; D003315:Cornea / Q000502:physiology*; D004547:Elastic Tissue / Q000502:physiology; D004548:Elasticity; D006801:Humans; D008875:Middle Aged