Multisite association by recombinant proteins can enhance binding selectivity. Preferential removal of immune complexes from serum by immobilized truncated FB analogues of the B domain from staphylococcal protein A.
Huston
J S
JS
Creative Biomolecules, Incorporated, Hopkinton, Massachusetts 01748.
Cohen
C
C
Maratea
D
D
Fields
F
F
Tai
M S
MS
Cabral-Denison
N
N
Juffras
R
R
Rueger
D C
DC
Ridge
R J
RJ
Oppermann
H
H
D000595:Amino Acid Sequence; D000936:Antigen-Antibody Complex / Q000097:blood / Q000302:isolation & purification* / Q000378:metabolism; D001665:Binding Sites; D055592:Biophysical Phenomena; D001703:Biophysics; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism; D066298:In Vitro Techniques; D007700:Kinetics; D008958:Models, Molecular; D008969:Molecular Sequence Data; D015202:Protein Engineering; D011994:Recombinant Proteins / Q000737:chemistry / Q000378:metabolism; D013205:Staphylococcal Protein A / Q000737:chemistry / Q000378:metabolism*
D000936:Antigen-Antibody Complex; D007074:Immunoglobulin G; D011994:Recombinant Proteins; D013205:Staphylococcal Protein A