Nutrition and genetic susceptibility to common diseases.
Genetic factors play a role in chronic disease and conditions such as coronary heart disease, hypertension, and obesity. Individual responses to nutritional factors involved in such conditions vary depending upon a person's genetic make-up. The role of individual genes is best understood for the hyperlipidemias that predispose to coronary heart disease. Until more and better information on gene-nutritional interactions is available, general population-wide recommendations regarding a prudent diet appear reasonable. At the same time, high risk screening for certain conditions such as the hyperlipidemias is appropriate.
Motulsky
A G
AG
Department of Medicine and Genetics, University of Washington, Seattle 98195.
D003327:Coronary Disease / Q000235:genetics*; D004032:Diet; D020022:Genetic Predisposition to Disease; D014644:Genetic Variation; D006801:Humans; D006950:Hyperlipidemia, Familial Combined / Q000235:genetics*; D006973:Hypertension / Q000235:genetics*; D009747:Nutritional Physiological Phenomena; D009765:Obesity / Q000235:genetics*