DNA technology.
Scientific developments in molecular biology enable clinical laboratory testing to directly examine genetic information coded in biologic specimens. These efforts, accomplished by the use of DNA probe technology in the in situ hybridization and other tests will allow for the specific identification of pathogens; recognition of genetic diseases; and the critical evaluation of the genetic basis of cancer. The authors discuss the concepts and uses of DNA testing.
Fernandes
J J
JJ
Department of Pathology, Philadelphia College of Osteopathic Medicine, Pa.
Coffman
N B
NB
D003001:Cloning, Molecular; D005784:Gene Amplification; D005821:Genetic Techniques; D005826:Genetics, Medical; D006801:Humans; D016296:Mutagenesis; D009693:Nucleic Acid Hybridization; D016133:Polymerase Chain Reaction; D011995:Recombination, Genetic