title: 12q13 abnormality in rhabdomyosarcoma. A nonrandom occurrence?
abstract: We describe two cases of rhabdomyosarcoma with a translocation involving 12q13 as the primary cytogenetic abnormality. Literature review of 35 cases has identified 3 other cases with this abnormality, and we speculate that this may be another nonrandom rearrangement in rhabdomyosarcoma.
authors.affiliation: Regional Cytogenetics Unit, St. James's University Hospital, Leeds, United Kingdom.
authors.forename: P
authors.initials: P
authors.lastname: Roberts
authors.forename: C F
authors.initials: CF
authors.lastname: Browne
authors.forename: I J
authors.initials: IJ
authors.lastname: Lewis
authors.forename: C C
authors.initials: CC
authors.lastname: Bailey
authors.forename: R D
authors.initials: RD
authors.lastname: Spicer
authors.forename: J
authors.initials: J
authors.lastname: Williams
authors.forename: G
authors.initials: G
authors.lastname: Batcup
mesh_terms: D000293:Adolescent; D002648:Child; D002881:Chromosomes, Human, Pair 12; D005260:Female; D006801:Humans; D008297:Male; D012208:Rhabdomyosarcoma / Q000235:genetics* / Q000628:therapy; D012983:Soft Tissue Neoplasms / Q000235:genetics* / Q000628:therapy; D013848:Thigh; D014178:Translocation, Genetic / Q000235:genetics*; D001749:Urinary Bladder Neoplasms / Q000235:genetics* / Q000628:therapy