Buflomedil intoxication: the little-known risk.
A life-threatening intoxication, requiring ventilatory support, is reported from the ingestion of 3.05 g of buflomedil, a peripheral vasodilator. Buflomedil at a dosage of 50 mg/kg weight produces seizures. Hypotension is not a specific symptom of intoxication. Buflomedil poisoning can be easily confused with other drugs, especially tricyclic antidepressants.
Martínez-Sierra
R
R
Clinical Pharmacology Unit, Faculty of Medicine, Hospital Regional Reina Sofía Córdoba, Spain.
Lara
B
B
Torres
A
A
D000328:Adult; D003975:Diazepam / Q000627:therapeutic use; D005260:Female; D006801:Humans; D011041:Poisoning / Q000188:drug therapy; D011759:Pyrrolidines / Q000506:poisoning*; D012640:Seizures / Q000139:chemically induced* / Q000188:drug therapy; D014665:Vasodilator Agents / Q000506:poisoning*
D011759:Pyrrolidines; D014665:Vasodilator Agents; D003975:Diazepam; C010651:buflomedil