Ascites: a portent of cardiopulmonary complications in the preeclamptic patient with the syndrome of hemolysis, elevated liver enzymes, and low platelets.
OBJECTIVE
Maternal ascites is frequently found at cesarean delivery in patients with severe preeclampsia or eclampsia expressed as hemolysis, elevated liver enzymes, and low platelets (HELLP syndrome). We attempted to determine whether large-volume maternal ascites present at cesarean delivery in HELLP syndrome patients is correlated with disease severity or with any specific form of increased maternal morbidity.


METHODS
For this retrospective case series, we reviewed the medical records of 190 patients and noted the presence or absence of large-volume maternal ascites, peripartum complications, laboratory data, and specific operative techniques.


RESULTS
The incidence of large-volume ascites in patients with HELLP syndrome who underwent abdominal delivery was approximately 10% in classes 1, 2, and 3. Compared with HELLP syndrome patients without ascites, those with HELLP-associated ascites at surgery had a significant sixfold increase in the incidence of congestive heart failure and a ninefold increase in the incidence of adult respiratory distress syndrome, both of which usually became clinically apparent within 24 hours postpartum. Those HELLP syndrome patients without ascites at surgery developed congestive heart failure or adult respiratory distress syndrome infrequently, and more than 24 hours postoperatively.


CONCLUSIONS
Cautious fluid administration and observation for cardiopulmonary deterioration are crucial in management of the critically ill, high-risk group of HELLP syndrome patients with large-volume ascites.
Woods
J B
JB
Department of Obstetrics and Gynecology, University of Mississippi Medical Center, Jackson.
Blake
P G
PG
Perry
K G
KG
Magann
E F
EF
Martin
R W
RW
Martin
J N
JN
D000328:Adult; D000743:Anemia, Hemolytic / Q000150:complications; D001201:Ascites / Q000150:complications*; D002585:Cesarean Section; D005260:Female; D006333:Heart Failure / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D008099:Liver / Q000201:enzymology; D011183:Postoperative Complications / Q000453:epidemiology*; D011225:Pre-Eclampsia / Q000150:complications*; D011247:Pregnancy; D011248:Pregnancy Complications; D011644:Puerperal Disorders; D012127:Respiratory Distress Syndrome, Newborn / Q000453:epidemiology*; D012189:Retrospective Studies; D013577:Syndrome; D013921:Thrombocytopenia / Q000150:complications