Endoscopic enhancement of the healing of high-risk colon anastomoses by low-power helium-neon laser. An experimental study.
Recent studies suggest that helium-neon (He-Ne) lasers at low energy can enhance wound healing in intestinal anastomoses. In this experimental study, we tested the strength and collagen concentration of high-risk anastomoses of the rat colon after endoscopic irradiation by helium-neon laser. Our results show that repeated helium-neon laser irradiation (1.9 J/cm2) increases the bursting strength of the anastomoses by almost 100% on the fourth postoperative day. This effect is not observed by increasing the radiation dose (6.4 J/cm2). Differences in collagen (hydroxyproline) concentration did not reach statistical significance.
Asencio-Arana
F
F
Department of Anatomy, University of Valencia, Spain.
Garcia-Fons
V
V
Molina-Andreu
E
E
Vidal-Martinez
J
J
Martinez-Soriano
F
F
D000714:Anastomosis, Surgical; D000818:Animals; D003094:Collagen / Q000378:metabolism; D003106:Colon / Q000378:metabolism / Q000503:physiopathology / Q000601:surgery*; D003113:Colonoscopy; D053685:Laser Therapy; D008297:Male; D011829:Radiation Dosage; D051381:Rats; D011919:Rats, Inbred Strains; D012307:Risk Factors; D013529:Surgical Wound Dehiscence / Q000517:prevention & control*; D013718:Tensile Strength; D014945:Wound Healing / Q000528:radiation effects*
D003094:Collagen