Burkitt cell leukemia with myelodysplasia as a presentation of HIV infection.
Hematologic manifestations of human immunodeficiency virus (HIV) infection include cytopenias, non-Hodgkin's lymphoma, and myelodysplasia. Acute lymphocytic leukemia has rarely been reported in association with HIV infection. We describe a patient who presented with Burkitt cell leukemia and myelodysplasia as her initial manifestation of HIV infection. The dysplastic features included circulating asymmetric binucleated red blood cells as well as pseudo Pelger-Huet cells. To the best of our knowledge, this has not been previously reported.
Sham
R L
RL
University of Rochester School of Medicine and Dentistry, Rochester General Hospital, Department of Medicine, New York 14621.
Bennett
J M
JM
D000328:Adult; D001706:Biopsy; D001853:Bone Marrow / Q000473:pathology; D002051:Burkitt Lymphoma / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D015658:HIV Infections / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D009190:Myelodysplastic Syndromes / Q000209:etiology*