title: Continuous quality improvement in chronic disease: a computerized medical record enables description of a severity index to evaluate outcomes in end-stage renal disease.
abstract: We have previously derived an index, based on retrospective data, for mortality in patients with end-stage renal disease (ESRD) treated by dialysis and transplantation. We used this index to calculate probability of death and rates of hospitalization, two measures of severity of illness, for 436 patients enrolled in our ESRD program after the original index was derived. Applied when ESRD treatment was initiated, it predicted future mortality and hospitalization rates. We then analyzed clinical characteristics, including variables in the predictive model, in all 718 patients enrolled in 3-year cohorts from 1976 to 1989. Over time, there was trend toward enrolling patients with a higher likelihood of dying, ie, more severely ill. The severity index facilitated description of the patients and their changing characteristics over time, and proved useful in comparing the degree of illness in different population groups.
authors.affiliation: Dialysis Clinic, Cincinnati, OH.
authors.forename: V E
authors.initials: VE
authors.lastname: Pollak
authors.forename: A
authors.initials: A
authors.lastname: Pesce
authors.forename: K S
authors.initials: KS
authors.lastname: Kant
mesh_terms: D015331:Cohort Studies; D015897:Comorbidity; D016208:Databases, Factual; D005260:Female; D005544:Forecasting; D006436:Hemodialysis Units, Hospital / Q000706:statistics & numerical data*; D006746:Hospital Bed Capacity, 500 and over; D006785:Hospitals, University / Q000706:statistics & numerical data*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000145:classification / Q000401:mortality* / Q000628:therapy; D008297:Male; D016347:Medical Records Systems, Computerized; D008875:Middle Aged; D015233:Models, Statistical; D009820:Ohio / Q000453:epidemiology; D017063:Outcome Assessment, Health Care; D011446:Prospective Studies; D012189:Retrospective Studies; D012720:Severity of Illness Index