Westiellamide, a bistratamide-related cyclic peptide from the blue-green alga Westiellopsis prolifica.
The isolation and structural elucidation of westiellamide [1] from the terrestrial blue-green alga Westiellopsis prolifica is described. This moderately cytotoxic cyclic peptide appears to be identical with a bistratamide-type marine natural product from the aplouso-branch ascidian Lissoclinum bistratum.
Prinsep
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Department of Chemistry, University of Hawaii, Honolulu 96822.
Moore
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Levine
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Patterson
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D000595:Amino Acid Sequence; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000458:Cyanobacteria / Q000737:chemistry*; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D015394:Molecular Structure; D010456:Peptides, Cyclic / Q000737:chemistry / Q000302:isolation & purification*; D014407:Tumor Cells, Cultured / Q000187:drug effects
D000970:Antineoplastic Agents; D010456:Peptides, Cyclic; C074972:westiellamide