Liver transplantation for acute fulminant hepatic failure.
Orthotopic liver transplantation (OLT) remains the only option for progressive acute fulminant hepatic failure (FHF). The overall one-year survival is approximately 58% versus 75% for all patients undergoing OLT. Nevertheless, this is superior to the results obtained with medical management alone, which carries a mortality of approximately 60-85%. Seven of 32 patients at Hartford Hospital (22%) received liver transplants for acute FHF; the one-year survival was 57%. Four of seven patients are alive with complete neurologic recovery. One case is presented in detail.
Alsina
A E
AE
Department of Surgery, Hartford Hospital, CT 06115.
Hull
D
D
Bartus
S A
SA
Schweizer
R T
RT
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006501:Hepatic Encephalopathy / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008099:Liver / Q000473:pathology; D008111:Liver Function Tests; D016031:Liver Transplantation / Q000473:pathology; D008875:Middle Aged; D011183:Postoperative Complications / Q000401:mortality* / Q000473:pathology; D015996:Survival Rate