[Rapid diagnosis of Chlamydia trachomatis using a DNA probe in a population with low risk of infection].
BACKGROUND
To assess the efficacy of a newer diagnostic technique for Chlamydia trachomatis and its usefulness as screening method in populations at low-risk for Chlamydia trachomatis infection.


METHODS
Open comparative trial between the EIA technique (Abbott Laboratories) and DNA gene probe (Gen Probe Diagnostic). A total of 1683 individuals (1630 women and 53 men) were screened with the two different techniques using samples obtained simultaneously.


RESULTS
Among women, 66 give a positive result either by one or another technique. The prevalence was 4.04%. Sensitivity of DNA probe when compared with EIA assay was 64% and specificity was 98.9%.


CONCLUSIONS
The DNA probe technique is faster than actual techniques and easy to do without major laboratory equipment. However, its price is high and its sensitivity poor in low-risk populations.
Rosales
M
M
Servicio de Medicina Preventiva y Salud Pública, Hospital Juan Canalejo, La Coruña.
Domínguez
V
V
Bonacho
I
I
Vidal
X
X
D002584:Cervix Uteri / Q000382:microbiology; D002690:Chlamydia Infections / Q000175:diagnosis* / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D015342:DNA Probes; D004269:DNA, Bacterial / Q000032:analysis*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D011237:Predictive Value of Tests; D012306:Risk; D012680:Sensitivity and Specificity; D013997:Time Factors; D014521:Urethra / Q000382:microbiology
D015342:DNA Probes; D004269:DNA, Bacterial
Diagnóstico rápido de Chlamydia trachomatis por sonda ADN-Probe en una problación con bajo riesgo de infección.