title: Efficiency of the left ventricle assist device Hemopump in cardiac fibrillation.
abstract: We have examined in sheep the efficiency of the Hemopump during ventricular fibrillation. Circulatory arrest was induced by electrical stimulation and maintained for 30 min. Haemodynamic measurements were recorded continuously and blood samples were taken before, during and after fibrillation to determine total body and myocardial metabolic activity. All hearts were defibrillated successfully after 30 min of fibrillation. During fibrillation, the Hemopump sustained a mean arterial pressure of about 60 mm Hg with a blood flow rate of about 2.3 litre min-1. These perfusion conditions were sufficient for maintenance of aerobic myocardial metabolism, but with a borderline circulatory supply to the total organism.
authors.affiliation: Department of Experimental Cardiology, University of Göttingen, FRG.
authors.forename: T
authors.initials: T
authors.lastname: Schröder
authors.forename: J P
authors.initials: JP
authors.lastname: Hering
authors.forename: P
authors.initials: P
authors.lastname: Uhlig
authors.forename: K H
authors.initials: KH
authors.lastname: Scholz
authors.forename: U
authors.initials: U
authors.lastname: Tebbe
authors.forename: H
authors.initials: H
authors.lastname: Kreuzer
authors.forename: G
authors.initials: G
authors.lastname: Hellige
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000502:physiology; D004195:Disease Models, Animal; D006323:Heart Arrest / Q000503:physiopathology / Q000628:therapy*; D006353:Heart-Assist Devices; D010101:Oxygen Consumption / Q000502:physiology; D011188:Potassium / Q000378:metabolism; D012039:Regional Blood Flow / Q000502:physiology; D012756:Sheep; D014693:Ventricular Fibrillation / Q000503:physiopathology / Q000628:therapy*
chemical_list: D011188:Potassium