Antibiotic prophylaxis in neurosurgery. The controlled trials.
Systemic antibiotics are effective in reducing the risk of infection after clean neurosurgical procedures. They are less effective in preventing shunt infection, but are strongly recommended in institutions experiencing a shunt infection rate exceeding 15%. The role for antibiotic prophylaxis using topical agents and in the prevention of meningitis associated with cerebrospinal fluid drainage is uncertain.
Haines
S J
SJ
Department of Neurosurgery, University of Minnesota Hospital and Clinic, Minneapolis.
D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000493:pharmacokinetics; D002557:Cerebrospinal Fluid Shunts; D002986:Clinical Trials as Topic / Q000379:methods*; D006801:Humans; D011292:Premedication; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000517:prevention & control*
D000900:Anti-Bacterial Agents