Studies on immunomodulatory properties of isoniazid: V. Influence of isoniazid on secretion of interleukin-1.
Isoniazid in vitro decreased interleukin-1 production by glass-adherent cells from the blood of healthy donors. The previously described modulation of T cell activation by isoniazid seems to be independent of decreased interleukin-1 secretion.
Kucharz
E J
EJ
Fourth Department of Internal Medicine, Silesian School of Medicine, Katowice, Poland.
Sierakowski
S J
SJ
D002455:Cell Division / Q000187:drug effects; D006801:Humans; D007375:Interleukin-1 / Q000378:metabolism*; D007538:Isoniazid / Q000276:immunology / Q000494:pharmacology*; D008070:Lipopolysaccharides / Q000276:immunology; D013601:T-Lymphocytes / Q000187:drug effects / Q000378:metabolism
D007375:Interleukin-1; D008070:Lipopolysaccharides; D007538:Isoniazid