CGRP as a marker of the climbing fibers during the development of the cerebellum in the rat.
Olivary fibers express CGRP-LI until the nest phase of their development and never in the next postnatal steps, that is, the "capuchon" stage. Together with other results presented in this volume regarding the postnatal development of CGRP binding sites in the cerebellar cortex, these immunohistologic findings suggest a role for CGRP in reshaping connectivity and in synapse stabilization of cerebellar circuitry during postnatal development.
Morara
S
S
Ist. Fisiologia Centri Nervosi CNR, Facoltá di Farmacia, Universitá di Milano, Italy.
Rosina
A
A
Provini
L
L
D000375:Aging / Q000502:physiology*; D000818:Animals; D000831:Animals, Newborn; D015415:Biomarkers; D015740:Calcitonin Gene-Related Peptide / Q000032:analysis*; D002525:Cerebellar Cortex / Q000166:cytology / Q000254:growth & development; D002531:Cerebellum / Q000166:cytology / Q000254:growth & development*; D007124:Immunoenzyme Techniques; D009412:Nerve Fibers / Q000502:physiology* / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains
D015415:Biomarkers; D015740:Calcitonin Gene-Related Peptide