Effect of feed type on the pharmacokinetic disposition of oxfendazole in sheep.
The plasma concentration profiles of oxfendazole (OFZ), fenbendazole (FBZ) and FBZ sulphone (FBZ.SO2) were measured followed intraruminal administration of OFZ at 5 mg kg-1 to Merino weaners fed either dry forage or grazed on pasture lucerne clover. Plasma concentrations of OFZ and FBZ were significantly lower in sheep given the dry forage.
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CSIRO Division of Animal Health, McMaster Laboratory, New South Wales, Australia.
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D000821:Animal Feed; D000818:Animals; D000871:Anthelmintics / Q000493:pharmacokinetics*; D001562:Benzimidazoles / Q000493:pharmacokinetics*; D002523:Edible Grain; D000455:Medicago sativa; D012756:Sheep / Q000378:metabolism*; D014908:Triticum
D000871:Anthelmintics; D001562:Benzimidazoles; C011030:oxfendazole