Axon guidance by molecular gradients.
In the past year, evidence indicating that some developing axons are guided to their targets, at least in part, by gradients of diffusible chemoattractants secreted by their target cells has continued to accumulate. It has also been shown for the first time that axons can orient in response to smooth gradients of immobilized substrate molecules.
Tessier-Lavigne
M
M
Department of Anatomy, University of California, San Francisco 94143-0452.
D000818:Animals; D001369:Axons / Q000502:physiology*; D006801:Humans; D009420:Nervous System / Q000166:cytology / Q000254:growth & development*; D009434:Neural Pathways / Q000166:cytology / Q000254:growth & development