title: Direct projections from the globus pallidus to the midbrain and pons in the cat.
abstract: Employing the anterograde and retrograde axonal tracing techniques with Phaseolus vulgaris leucoagglutinin and cholera toxin B subunit, we demonstrated direct projections from the globus pallidus (GP) to the midbrain and pons in the cat. Cells of origin of these projections were localized in the caudal 2/3 of the GP, and their major target sites included the peripeduncular region, nucleus of the brachium of the inferior colliculus, para-lateral lemniscal zone, nucleus sagulum, external and pericentral nuclei of the inferior colliculus, and cuneiform nucleus. A combination of retrograde axonal tracing and immunohistochemistry for choline acetyltransferase revealed that GP neurons giving rise to such descending projections were primarily non-cholinergic.
authors.affiliation: Department of Morphological Brain Science, Faculty of Medicine, Kyoto University, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Shinonaga
authors.forename: M
authors.initials: M
authors.lastname: Takada
authors.forename: R
authors.initials: R
authors.lastname: Ogawa-Meguro
authors.forename: Y
authors.initials: Y
authors.lastname: Ikai
authors.forename: N
authors.initials: N
authors.lastname: Mizuno
mesh_terms: D000818:Animals; D002415:Cats; D002795:Choline O-Acetyltransferase / Q000378:metabolism; D005917:Globus Pallidus / Q000166:cytology / Q000502:physiology*; D007150:Immunohistochemistry; D008636:Mesencephalon / Q000166:cytology / Q000502:physiology*; D009434:Neural Pathways / Q000166:cytology / Q000502:physiology; D010835:Phytohemagglutinins; D011149:Pons / Q000166:cytology / Q000502:physiology*; D013238:Stereotaxic Techniques
chemical_list: D010835:Phytohemagglutinins; C100156:leukoagglutinins, plants; D002795:Choline O-Acetyltransferase