title: Blindness associated with toxoplasmosis in canaries.
abstract: Seven of 30 canaries in an aviary in New Zealand developed ophthalmic problems. Clinically, 5 birds had unilateral and 2 birds had bilateral lesions characterized by conjunctivitis, crusty exudates on eyelids, and collapse of the eyeball. Microscopic lesions in 12 of 14 eyes examined included inflammation of the choroid and retina, with osseous replacement of the globe in some. Numerous Toxoplasma gondii tachyzoites were seen in the detached retina and vitreous humor of acutely affected birds. The diagnosis of toxoplasmosis was confirmed by immunohistochemical staining with T gondii antiserum. Affected birds had encephalitis, and T gondii was localized in the brains of these by immunohistochemical examination and by use of bioassays in mice. Toxoplasmosis should be considered in differential diagnosis of ophthalmitis in canaries.
authors.affiliation: Animal Health Laboratory, Palmerston North, New Zealand.
authors.forename: M C
authors.initials: MC
authors.lastname: Vickers
authors.forename: W J
authors.initials: WJ
authors.lastname: Hartley
authors.forename: R W
authors.initials: RW
authors.lastname: Mason
authors.forename: J P
authors.initials: JP
authors.lastname: Dubey
authors.forename: L
authors.initials: L
authors.lastname: Schollam
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D001715:Bird Diseases / Q000209:etiology*; D001766:Blindness / Q000209:etiology / Q000662:veterinary*; D001921:Brain / Q000469:parasitology / Q000473:pathology; D002171:Canaries; D005123:Eye / Q000473:pathology; D005260:Female; D008297:Male; D051379:Mice; D014122:Toxoplasma / Q000276:immunology / Q000302:isolation & purification; D014124:Toxoplasmosis, Animal / Q000150:complications*
chemical_list: D000913:Antibodies, Protozoan