The reaction of copper and other projectile metals in body tissues.
To determine the effect of copper in tissue, copper specimens, along with other metals commonly used in firearm projectiles, were implanted into rats. Copper consistently produced a necrotic, abscesslike reaction in all tissues tested. Nickel produced a similar reaction, although of lesser magnitude. Aluminum, zinc, and lead produced no significant tissue reaction.
Wigle
R L
RL
Department of Surgery, Rhode Island Hospital, Providence.
D000038:Abscess / Q000209:etiology / Q000503:physiopathology; D000818:Animals; D003300:Copper; D003964:Diaphragm / Q000187:drug effects / Q000503:physiopathology; D005549:Foreign-Body Reaction / Q000473:pathology / Q000503:physiopathology*; D007082:Ileum / Q000187:drug effects / Q000503:physiopathology; D008297:Male; D008670:Metals; D051381:Rats; D011919:Rats, Inbred Strains
D008670:Metals; D003300:Copper