title: Heat shock response in Drosophila.
abstract: Major alterations in genetic activity have been observed in every organism after exposure to abnormally high temperatures. This phenomenon, called the heat shock response, was discovered in the fruit fly Drosophila. Studies with this organism led to the discovery of the heat shock proteins, whose genes were among the first eukaryotic genes to be cloned. Several of the most important aspects of the regulation of the heat shock response and of the functions of the heat shock proteins have been unraveled in Drosophila.
authors.affiliation: Département de Zoologie et Biologie Animale, Université de Genève, Chêne-Bougeries, Switzerland.
authors.forename: D
authors.initials: D
authors.lastname: Pauli
authors.forename: A P
authors.initials: AP
authors.lastname: Arrigo
authors.forename: A
authors.initials: A
authors.lastname: Tissières
mesh_terms: D000818:Animals; D004330:Drosophila; D006360:Heat-Shock Proteins / Q000235:genetics / Q000502:physiology*; D006358:Hot Temperature; D006801:Humans
chemical_list: D006360:Heat-Shock Proteins