Ising model for B-Z transition in supercoiled DNA.
The possible existence of nucleic acids in right-handed and left-handed helical forms is considered. A statistical mechanical model is developed to obtain an expression for a change in twist during helical transformation in terms of corresponding free energies and linking for a supercoiled DNA. The theoretically predicted values are compared with those determined experimentally. The physico-chemical significance of the parameters is discussed.
Ghosh
S
S
Department of Biophysics, University of Delhi South Campus, India.
D001482:Base Composition; D004278:DNA, Superhelical / Q000737:chemistry*; D008433:Mathematics; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D010957:Plasmids / Q000235:genetics
D004278:DNA, Superhelical