title: [Histomorphology of pelvic floor muscles in women with urinary incontinence].
abstract: Success of urinary incontinence surgery so far depended primarily on the intensity and quality of preoperative diagnosis, the resulting choice of techniques, suture material, and the surgeon's skills. The role played by tissue available from the patient herself, however, had not been adequately considered, although such an assessment would have been of major relevance to all methods using autogenic tissue. Preliminary histological-histochemical and morphometric investigations of pubococcygeal muscles of ten patients revealed unambiguous right-left differences with regard to muscle quality and fibre typing, mean cross-section area of muscle fibres, and connective tissue response up to degeneration and also concerning replacement of striated muscles by smooth muscles. Further studies into collagen metabolism are likely to enable more reliable prognosis of operations for urinary incontinence.
authors.affiliation: Frauenklinik, Medizinischen Fakultät (Charité), Humboldt-Universität zu Berlin.
authors.forename: W
authors.initials: W
authors.lastname: Fischer
authors.forename: C
authors.initials: C
authors.lastname: Pfister
authors.forename: R
authors.initials: R
authors.lastname: Tunn
mesh_terms: D000328:Adult; D003094:Collagen / Q000032:analysis; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008856:Microscopy, Fluorescence; D008875:Middle Aged; D009132:Muscles / Q000473:pathology*; D010388:Pelvis; D011975:Receptors, Mitogen / Q000032:analysis; D014550:Urinary Incontinence, Stress / Q000473:pathology*
chemical_list: D011975:Receptors, Mitogen; D003094:Collagen
vernacular_title: Zur Histomorphologie der Beckenbodenmuskulatur bei Frauen mit Harninkontinenz.