title: Chromosomal localization of human O6-methylguanine-DNA methyltransferase (MGMT) gene by in situ hybridization.
abstract: Recombinant lambda phage DNA containing segments of human O6-methylguanine-DNA transferase gene was employed to localize this gene among the human chromosomes using non-radioactive in situ hybridization technique. This gene was found to be present at the telomeric end, 26q, of the long arm of the chromosome 10.
authors.affiliation: MGC Department of Radiation Genetics and Chemical Mutagenesis, State University of Leiden, The Netherlands.
authors.forename: A T
authors.initials: AT
authors.lastname: Natarajan
authors.forename: S
authors.initials: S
authors.lastname: Vermeulen
authors.forename: F
authors.initials: F
authors.lastname: Darroudi
authors.forename: M B
authors.initials: MB
authors.lastname: Valentine
authors.forename: T P
authors.initials: TP
authors.lastname: Brent
authors.forename: S
authors.initials: S
authors.lastname: Mitra
authors.forename: K
authors.initials: K
authors.lastname: Tano
mesh_terms: D002874:Chromosome Mapping / Q000379:methods*; D002879:Chromosomes, Human, Pair 10; D004247:DNA / Q000235:genetics; D006801:Humans; D008780:Methyltransferases / Q000235:genetics*; D009693:Nucleic Acid Hybridization; D019853:O(6)-Methylguanine-DNA Methyltransferase
chemical_list: D004247:DNA; D008780:Methyltransferases; D019853:O(6)-Methylguanine-DNA Methyltransferase