title: [Clinical pharmacology: current status and perspectives].
abstract: In view of the ever increasing complexity of individualized pharmacotherapy, the study of new and potent drugs in man and the misuse and abuse of drugs, WHO-Study Group reports and a recent enquiry in Belgium, France and W. Germany stress that the development of clinical pharmacology is an absolute necessity for patients, physicians, health authorities, the pharmaceutical industry and society at large. It seems this development could be optimally achieved by setting up, within Services of General Medicine or Internal Medicine of University Hospitals and large Public Hospitals, autonomous Units of Clinical Pharmacology with the responsibility to take an active part: a) at the service level: 1) in patient care, either directly in general medical services or drug problem oriented consultations, or indirectly through consultative functions and pharmacotherapeutic conferences; 2) in drug monitoring services, management of cases of overdose, drug information, drug utilization surveys, pharmaco-epidemiology, ethical committees, formulary committees, drug regulatory agencies and studies of Phase I, II and III; b) at the teaching level: 1) in courses of clinical pharmacology sui generis, to undergraduates, in close collaboration with the University Department of Pharmacology; 2) at the postgraduate level, as a specialty in se, and as part of the training in medical specialties and at the level of continuing education of general practitioners and specialists; c) at the research level: 1) in clinical pharmacokinetic studies, with special attention to interindividual variability and genetic factors, to drug concentration/effect studies, to drug interactions, and in pharmacodynamic studies, in view of the development of new approaches in the study of drug-receptor interactions; 2) in the design, realization and evaluation of Phase I, II and III studies, clinical trials and multicenter drug studies.
authors.affiliation: J.F. & C. Heymans Instituut voor Farmacologie, Universiteit Gent.
authors.forename: A F
authors.initials: AF
authors.lastname: De Schaepdryver
mesh_terms: D001530:Belgium; D004341:Drug Evaluation; D004345:Drug Industry; D004358:Drug Therapy; D004512:Education, Pharmacy; D005602:France; D005858:Germany; D006801:Humans; D010601:Pharmacology, Clinical / Q000193:education / Q000639:trends*; D012017:Referral and Consultation; D012106:Research
vernacular_title: Klinische farmacologie: vaststellingen en vooruitzichten.