title: Evidence for a pseudoautosomal locus for schizophrenia. I: A replication study using phenotype analysis.
abstract: A locus for schizophrenia within the pseudoautosomal region of chromosomes X and Y has been suggested by Crow on the basis of epidemiological data. The present report replicates this finding in a sample of 38 French multiply affected families with schizophrenia. Sibship and pairwise analysis, with or without weighted-pair correction, with three different systems of family classifications, showed there to be an excess of same-sex pairs in paternally derived sibships, as predicted by the pseudoautosomal hypothesis.
authors.affiliation: Laboratoire de'anthropologie biologique, INSERM V ISS, Université Paris VII, France.
authors.forename: P
authors.initials: P
authors.lastname: Gorwood
authors.forename: M
authors.initials: M
authors.lastname: Leboyer
authors.forename: T
authors.initials: T
authors.lastname: d'Amato
authors.forename: M
authors.initials: M
authors.lastname: Jay
authors.forename: D
authors.initials: D
authors.lastname: Campion
authors.forename: D
authors.initials: D
authors.lastname: Hillaire
authors.forename: J
authors.initials: J
authors.lastname: Mallet
authors.forename: J
authors.initials: J
authors.lastname: Feingold
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D010641:Phenotype; D012559:Schizophrenia / Q000235:genetics*; D012737:Sex Factors