title: MRI assessment of anterior callosotomy in the treatment of pharmacoresistant epilepsy.
abstract: Section of the anterior two-thirds of the corpus callosum is a well-known treatment of some forms of epilepsy of long duration resistant to anti-epileptic drugs and dangerous for the patient (tonic and atonic seizures). The aim of this functional surgery is to obtain the most complete rostral and caudal section of the corpus callosum without risk of disconnection syndrome. Callosotomy is seldom performed in Europe. We present our experience of magnetic resonance imaging (MRI) in the pre- and postoperative assessment of 6 patients who underwent anterior callosotomy and were followed up for more than six months. Our results were encouraging with considerable improvement of the patients' social life.
authors.affiliation: Service de neurochirurgie, CHRU de Dijon, hôpital général, France.
authors.forename: N
authors.initials: N
authors.lastname: Chadan
authors.forename: J L
authors.initials: JL
authors.lastname: Sautreaux
authors.forename: M
authors.initials: M
authors.lastname: Giroud
authors.forename: D
authors.initials: D
authors.lastname: Martin
authors.forename: D
authors.initials: D
authors.lastname: Binnert
authors.forename: R
authors.initials: R
authors.lastname: Dumas
authors.forename: A
authors.initials: A
authors.lastname: Thierry
mesh_terms: D000293:Adolescent; D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D002648:Child; D003071:Cognition; D003337:Corpus Callosum / Q000473:pathology / Q000601:surgery*; D004569:Electroencephalography; D017034:Epilepsy, Frontal Lobe / Q000188:drug therapy / Q000601:surgery*; D004829:Epilepsy, Generalized / Q000188:drug therapy / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012008:Recurrence
chemical_list: D000927:Anticonvulsants