title: Prospective, controlled, double-blind study of i.v. tenoxicam for analgesia after thoracotomy.
abstract: We have shown that a single i.v. dose of tenoxicam 20 mg, after thoracotomy, when compared with placebo in 20 patients (with one exclusion), was associated with a reduction in consumption of papaveretum, assessed by patient-controlled analgesia, of 2.2 mg h-1 (22%) to 4 h and 1.4 mg h-1 (23%) to 12 h after operation (repeated measures analysis of variance: P less than 0.01). There was no reduction from 12 to 24 h. There was no significant difference between groups in pain scores or in side effects.
authors.affiliation: Department of Anaesthesia, Green Lane Hospital, Auckland, New Zealand.
authors.forename: A F
authors.initials: AF
authors.lastname: Merry
authors.forename: G J
authors.initials: GJ
authors.lastname: Wardall
authors.forename: R J
authors.initials: RJ
authors.lastname: Cameron
authors.forename: M J
authors.initials: MJ
authors.lastname: Peskett
authors.forename: C J
authors.initials: CJ
authors.lastname: Wild
mesh_terms: D000328:Adult; D000368:Aged; D000698:Analgesia / Q000379:methods*; D016058:Analgesia, Patient-Controlled; D000894:Anti-Inflammatory Agents, Non-Steroidal; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009892:Opium; D010149:Postoperative Pain / Q000188:drug therapy*; D010894:Piroxicam / Q000031:analogs & derivatives*; D011446:Prospective Studies; D013908:Thoracotomy
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D010894:Piroxicam; D009892:Opium; C032801:tenoxicam