title: Is obstetric and neonatal outcome worse in fetuses who fail to reach their own growth potential?
abstract: OBJECTIVE
  To determine the perinatal outcome of fetuses who had birthweights less than that expected from early third trimester ultrasound scanning.
  
  
  METHODS
  Retrospective estimation of centile fetal weight at early third trimester ultrasound scanning compared with actual centile birthweight corrected for gestational age, parity and sex.
  
  
  METHODS
  Teaching Hospital Obstetric Unit, London.
  
  
  METHODS
  197 unselected women with singleton cephalic pregnancies who were delivered at term in our unit between October 1989 and May 1990.
  
  
  METHODS
  CTG abnormality, need for fetal blood sampling in labour, meconium-staining of the amniotic fluid, mode of delivery, Apgar scores at 1 and 5 min, need for transfer of baby to neonatal unit, and need for neonatal intubation of the neonate at delivery.
  
  
  RESULTS
  An actual birthweight greater than 5% less than the birthweight estimated from ultrasound scanning identified 44 babies (22%) with an increased risk of CTG abnormalities (chi 2 = 8.38, P less than 0.0025; Odds ratio (OR) = 2.54; 95% CI 1.36 to 4.78) and need for operative delivery (chi 2 = 5.81, P less than 0.0125; OR = 1.94; 95% CI 1.15 to 3.27), when compared with the remainder of the sample. Overall 14 (32%) of this group had birthweights above the 50th centile. A group of 44 babies selected as being the smallest for gestational age, without reference to growth pattern, had a similar excess morbidity. (All this group had birthweights below the 39th centile).
  
  
  CONCLUSIONS
  This study supports the hypothesis that in-utero fetal growth pattern is as important for perinatal outcome as being small for gestational age per se.
authors.affiliation: Department of Obstetrics and Gynaecology, Charing Cross and Westminster Medical School, West London Hospital, UK.
authors.forename: P J
authors.initials: PJ
authors.lastname: Danielian
authors.forename: A C
authors.initials: AC
authors.lastname: Allman
authors.forename: P J
authors.initials: PJ
authors.lastname: Steer
mesh_terms: D001724:Birth Weight; D005314:Embryonic and Fetal Development; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011256:Pregnancy Outcome; D011263:Pregnancy Trimester, Third; D012189:Retrospective Studies; D012307:Risk Factors; D012680:Sensitivity and Specificity; D016216:Ultrasonography, Prenatal