title: An evaluation of Lawsonia alba extract as hepatoprotective agent.
abstract: The hepatoprotective activity of an ethanol-water (1:1) extract of Lawsonia alba has been studied against CCl4-induced liver toxicity. The effects of the extract on hexobarbitone-induced sleep, BSP clearance, and on certain biochemical parameters indicated its protective role. There was no effect on bile flow. The extract did not show any signs of toxicity and the minimum lethal dose was greater than 2.0 g/kg p.o. in mice.
authors.affiliation: Department of Pharmacology, Regional Research Laboratory, Jammu Twai, India.
authors.forename: K K
authors.initials: KK
authors.lastname: Anand
authors.forename: B
authors.initials: B
authors.lastname: Singh
authors.forename: D
authors.initials: D
authors.lastname: Chand
authors.forename: B K
authors.initials: BK
authors.lastname: Chandan
mesh_terms: D000818:Animals; D001646:Bile / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008107:Liver Diseases / Q000188:drug therapy*; D008297:Male; D010936:Plant Extracts / Q000627:therapeutic use* / Q000633:toxicity; D010946:Plants, Medicinal; D051381:Rats; D012890:Sleep / Q000187:drug effects
chemical_list: D010936:Plant Extracts