title: [Primary antibiotic treatment of corneal ulcers in contact lens patients].
abstract: Two patient histories show that the therapy of contact lens corneal ulcers is complicated by bacterial resistance and mixed infection. To start an effective therapy against pseudomonas, gram-negative as well as gram-positive germs, a primary combination of tobramycin with fusidic acid seems to us as reasonable. Because of possible resistance to these antibiotics a smear should be taken from the ulcer and the contact lens case before therapy is begun and the clinical evolution must be controlled. In the choice of the antibiotics, the actual state of resistance and commercial availability was taken into account.
authors.affiliation: Universitätsaugenklinik Basel.
authors.forename: E
authors.initials: E
authors.lastname: Willa
authors.forename: R
authors.initials: R
authors.lastname: Osusky
authors.forename: B
authors.initials: B
authors.lastname: Zbinden
authors.forename: B
authors.initials: B
authors.lastname: Haab
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D003261:Contact Lenses; D003320:Corneal Ulcer / Q000188:drug therapy* / Q000382:microbiology; D004352:Drug Resistance, Microbial; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013290:Streptococcal Infections / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Antibiotische Primärbehandlung von Hornhautulzera bei Kontaktlinsenträgern.