title: Crossed signals: oncogenic transcription factors.
abstract: Transcription factors operate at key regulatory junctions in the cell's responses to diverse extracellular stimuli. We discuss how the transforming activity of mutated transcription factors encoded by several oncogenes (v-erbA, v-fos, v-jun and v-rel) may result in part from a loss of the integrated response to the signalling network.
authors.affiliation: Roche Institute of Molecular Biology, Department of Molecular Oncology and Virology, Nutley, New Jersey 07110.
authors.forename: D
authors.initials: D
authors.lastname: Forrest
authors.forename: T
authors.initials: T
authors.lastname: Curran
mesh_terms: D016762:Genes, fos; D016758:Genes, jun; D009154:Mutation; D009857:Oncogenes; D015398:Signal Transduction; D014157:Transcription Factors
chemical_list: D014157:Transcription Factors