Role of agglomeration in calcium oxalate monohydrate urolith development.
Formation of agglomerates of calcium oxalate monohydrate (COM) crystals on semi-batch precipitation performed at conditions relevant to urolithiasis (37 degrees C, pH = 6, initial ratio [Ca]/[Ox] = 10), but without any specific admixture, was followed by both optical and electron microscopy. COM crystals formed on precipitation developed into large agglomerates consisting of intergrown crystals by a mechanism of primary agglomeration. Primary agglomeration of COM crystals represents an important mechanism of COM renal calculi growth.
Grases
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University of the Balearic Islands, Department of Chemistry, Palma de Mallorca, Spain.
Millan
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A
Söhnel
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O
D002129:Calcium Oxalate / Q000737:chemistry*; D011232:Chemical Precipitation; D003460:Crystallization; D006801:Humans; D066298:In Vitro Techniques; D008855:Microscopy, Electron, Scanning; D014545:Urinary Calculi / Q000737:chemistry* / Q000209:etiology*
D002129:Calcium Oxalate