[Septic granulomatosis (chronic granulomatous disease = CGD) in the jaw area. A case report].
A rare case of chronic granulomatous disease with manifestation in the mandible is presented. A 10-year-old boy showed the clinical picture of osteomyelitis without paresthesia (Vincent syndrome). Diagnosis was done by the nitroblue tetrazolium test (NBT) and by demonstration of a complete cytochrome-b deficiency of the granulocytes. In septic granulomatosis a continuous application of Sulfamethoxazol-Trimetoprim is recommended for prophylaxis of infection. For treatment of infection further antibiotics who pass into the granulocytes like rifampicin and fosfomycin are necessary. Oral surgical procedures request a careful tissue handling and a tight wound closure.
Herrmann
A
A
Klinik und Poliklinik für Mund-Kiefer-Gesichtschirurgie, Heidelberg, Bundesrepublik Deutschland.
Zöller
J
J
Böhler
T
T
Born
I A
IA
D002648:Child; D003131:Combined Modality Therapy; D003573:Cytochrome b Group / Q000172:deficiency; D006105:Granulomatous Disease, Chronic / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D006801:Humans; D008297:Male; D008334:Mandible / Q000000981:diagnostic imaging / Q000473:pathology; D008336:Mandibular Diseases / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D009580:Nitroblue Tetrazolium; D010019:Osteomyelitis / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D011862:Radiography, Panoramic
D003573:Cytochrome b Group; D009580:Nitroblue Tetrazolium
Die septische Granulomatose (chronic granulomatous disease = CGD) im Kieferbereich. Ein Fallbericht.