title: The effect of preoperative needle abrasion of the recipient site on survival of autologous free fat grafts in rats.
abstract: Pads of fat ranging from 670-1758 mg in weight were taken from the right groins of 20 rats and implanted subcutaneously over their right pectoral muscles. One week previously the recipient site on the thorax had been abraded with a needle in 10 of the rats. After three months the transplanted fat was taken out, weighed, and examined histologically by light microscopy. Regional tissue blood flow in the transplanted fat and in the fat from the left groin was measured by the microsphere technique. The amount of surviving fat and blood flow in the fat transplanted to an abraded recipient site was significantly higher than in the control group after three months. We conclude that preoperative needle abrasion of the recipient site may increase the chance of revascularisation and survival of the transplanted fat in rats.
authors.affiliation: Surgical Research Laboratory, Haukeland University Hospital, Bergen, Norway.
authors.forename: F
authors.initials: F
authors.lastname: Samdal
authors.forename: K C
authors.initials: KC
authors.lastname: Skolleborg
authors.forename: B
authors.initials: B
authors.lastname: Berthelsen
mesh_terms: D000273:Adipose Tissue / Q000473:pathology / Q000637:transplantation*; D000818:Animals; D006085:Graft Survival; D008297:Male; D009339:Needles; D011300:Preoperative Care; D051381:Rats; D011919:Rats, Inbred Strains; D012039:Regional Blood Flow; D012867:Skin / Q000098:blood supply; D014182:Transplantation, Autologous