title: [Long-term phenytoin (Diphedan) therapy leading to IgA nephropathy].
abstract: A single case of IgA nephropathy with a concomitant tubulointerstitial nephritis, developing during a long-term phenytoin therapy is reported. The prolonged phenytoin therapy did neither prevent the transitional increases of serum IgA level nor ward off deterioration of the histological alterations. This case suggests that acute tubulointerstitial nephritis may have played a role in the mesangial trapping of IgA immunocomplexes.
authors.affiliation: Pécsi Orvostudományi Egyetem, II. sz. Belgyógyászati Klinika, Pécs.
authors.forename: A
authors.initials: A
authors.lastname: Háber
authors.forename: J
authors.initials: J
authors.lastname: Nagy
authors.forename: G
authors.initials: G
authors.lastname: Deák
authors.forename: T
authors.initials: T
authors.lastname: Süle
mesh_terms: D000328:Adult; D004827:Epilepsy / Q000188:drug therapy; D005922:Glomerulonephritis, IGA / Q000139:chemically induced*; D006801:Humans; D008297:Male; D009395:Nephritis, Interstitial / Q000139:chemically induced*; D010672:Phenytoin / Q000008:administration & dosage* / Q000009:adverse effects
chemical_list: D010672:Phenytoin
vernacular_title: Tartós phenytoin (Diphedan) szedés mellett kialakult IgA nephropathia.