Controlled ultraviolet irradiation generates endothelial damage without affecting the nerve terminals of the cerebral artery in cats.
The vesicles of adventitial autonomic nerve terminals were examined quantitatively under an electron microscope in controlled ultraviolet ray (UV)-irradiated cerebral vessels. Five cats whose basilar arteries were irradiated with UV (UV group) and 5 cats whose basilar arteries were irradiated with visible rays (control group) were compared. Endothelial vacuolation was observed only in the UV group. There was no statistically significant difference in the diameters of the dense-cored vesicles, related to noradrenaline, and clear vesicles, related to acetylcholine, between the two groups. It is concluded that controlled UV irradiation which generates endothelial damage does not affect the vascular adventitia ultrastructurally.
Isozumi
K
K
Department of Neurology, School of Medicine, Keio University, Tokyo, Japan.
Gotoh
F
F
Koto
A
A
Suzuki
N
N
Tsuzuki
Y
Y
D000109:Acetylcholine / Q000502:physiology; D000818:Animals; D001488:Basilar Artery / Q000294:innervation / Q000528:radiation effects* / Q000648:ultrastructure; D002415:Cats; D004730:Endothelium, Vascular / Q000528:radiation effects* / Q000648:ultrastructure; D005260:Female; D007003:Hypoglycemia / Q000473:pathology*; D008027:Light; D008297:Male; D008854:Microscopy, Electron; D009411:Nerve Endings / Q000187:drug effects*; D009638:Norepinephrine / Q000502:physiology; D011833:Radiation Injuries, Experimental / Q000473:pathology*; D014466:Ultraviolet Rays; D014617:Vacuoles / Q000648:ultrastructure
D000109:Acetylcholine; D009638:Norepinephrine