title: Recurrent intra-cranial granulomata presenting as space-occupying lesions in a patient with common variable immunodeficiency.
abstract: A patient with profound panhypogammaglobulinaemia due to common variable immunodeficiency developed two discrete intra-cranial space-occupying lesions, 10 years apart, requiring craniotomy. Histological examination revealed the intra-cranial masses to be granulomata of unknown aetiology on both occasions.
authors.affiliation: Department of Immunology, John Radcliffe Hospital, Oxford, UK.
authors.forename: S A
authors.initials: SA
authors.lastname: Misbah
authors.forename: G P
authors.initials: GP
authors.lastname: Spickett
authors.forename: M M
authors.initials: MM
authors.lastname: Esiri
authors.forename: J T
authors.initials: JT
authors.lastname: Hughes
authors.forename: W B
authors.initials: WB
authors.lastname: Matthews
authors.forename: R A
authors.initials: RA
authors.lastname: Thompson
authors.forename: H M
authors.initials: HM
authors.lastname: Chapel
mesh_terms: D000293:Adolescent; D000361:Agammaglobulinemia / Q000150:complications*; D001927:Brain Diseases / Q000209:etiology* / Q000473:pathology; D005260:Female; D006099:Granuloma / Q000209:etiology* / Q000473:pathology; D006801:Humans; D012008:Recurrence