title: Weight loss and 2-y follow-up for 80 morbidly obese patients treated with intensive very-low-calorie diet and an education program.
abstract: Eighty morbidly obese individuals consecutively enrolled in a comprehensive very-low-calorie diet (VLCD) program were evaluated. Patients' mean initial body mass index was 45.5 kg/m2 and they lost 35.3 kg in 26 wk. Serum total cholesterol, low-density-lipoprotein cholesterol, and triglycerides decreased by 15.0%, 17.0%, and 14%, respectively. Systolic and diastolic blood pressure decreased by 8.7% and 10.0%, respectively. The 46 individuals completing 2-y follow-up were maintaining 48.0 +/- 7.6% (means +/- SE) of their weight loss. Morbidly obese persons lost substantial amounts of weight using a comprehensive VLCD program, reduced risk factors associated with obesity, and had encouraging long-term results, with 48% of weight loss maintained at 2 y of follow-up.
authors.affiliation: Endocrine-Metabolic Section, VA Medical Center, Lexington, KY 40511.
authors.forename: J W
authors.initials: JW
authors.lastname: Anderson
authors.forename: V L
authors.initials: VL
authors.lastname: Brinkman
authors.forename: C C
authors.initials: CC
authors.lastname: Hamilton
mesh_terms: D000328:Adult; D001794:Blood Pressure; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D004038:Diet, Reducing / Q000009:adverse effects; D002149:Energy Intake; D004734:Energy Metabolism; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000178:diet therapy / Q000628:therapy*; D010353:Patient Education as Topic; D016896:Treatment Outcome; D014280:Triglycerides / Q000097:blood; D015431:Weight Loss
chemical_list: D008078:Cholesterol, LDL; D014280:Triglycerides; D002784:Cholesterol