title: Theileria sergenti proliferates in SCID mice with bovine erythrocyte transfusion.
abstract: The unavailability of in vitro or in vivo experimental systems has been the major factor hampering the progress of research studies on Theileria sergenti, causative agent of theileriosis, a major disease of cattle in Japan. We report the first successful propagation of T. sergenti in SCID mice into which uninfected bovine erythrocytes (Bo-RBC) were supplied periodically. The infectivity of T. sergenti proliferated in an SCID mouse was ascertained by successful transfer of infection into another SCID mouse into which uninfected Bo-RBC were supplied periodically.
authors.affiliation: School of Veterinary Medicine, Rakuno Gakuen University, Ebetsu, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Tsuji
authors.forename: K
authors.initials: K
authors.lastname: Hagiwara
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
authors.forename: C
authors.initials: C
authors.lastname: Ishihara
authors.forename: I
authors.initials: I
authors.lastname: Azuma
authors.forename: W A
authors.initials: WA
authors.lastname: Siddiqui
mesh_terms: D000818:Animals; D002417:Cattle; D004195:Disease Models, Animal; D004912:Erythrocytes / Q000469:parasitology*; D008297:Male; D051379:Mice; D016513:Mice, SCID; D013045:Species Specificity; D016794:Theileria / Q000254:growth & development*; D013801:Theileriasis / Q000097:blood*