title: MW/Pharm, an integrated software package for drug dosage regimen calculation and therapeutic drug monitoring.
abstract: The pharmacokinetic software package MW/Pharm offers an interactive, user-friendly program which gives rapid answers in clinical practice. It comprises a database with pharmacokinetic parameters of 180 drugs, a medication history database, and procedures for an individual drug dosage regimen calculation. The included curve-fitting facilities allow estimation of pharmacokinetic parameters on the basis of medication history, taking into account a varying status of the patient with respect to body weight and kidney function, optionally using a Bayesian procedure. The module KinBes performs the evaluation of bioavailability studies, including various methods, and an extensive statistical evaluation of bioequivalence.
authors.affiliation: Department of Pharmacology and Therapeutics, University of Groningen, The Netherlands.
authors.forename: J H
authors.initials: JH
authors.lastname: Proost
authors.forename: D K
authors.initials: DK
authors.lastname: Meijer
mesh_terms: D000465:Algorithms; D001499:Bayes Theorem; D001682:Biological Availability; D001835:Body Weight; D016303:Clinical Pharmacy Information Systems / Q000592:standards*; D016903:Drug Monitoring; D006801:Humans; D007668:Kidney / Q000502:physiology; D008433:Mathematics; D008487:Medical History Taking; D004364:Pharmaceutical Preparations / Q000008:administration & dosage*; D010599:Pharmacokinetics; D012984:Software / Q000592:standards*; D013810:Therapeutic Equivalency
chemical_list: D004364:Pharmaceutical Preparations