Treatment resistant depression in the elderly: three cases.
We report three cases of severe depression in whom ECT was relatively contraindicated, who responded dramatically to switching lithium and fluoxetine to lithium and lofepramine. Possible mechanisms are discussed.
Seymour
J
J
Rosemary Day Hospital, St. James's University Hospital, Leeds, UK.
Wattis
J P
JP
D000368:Aged; D000369:Aged, 80 and over; D003866:Depressive Disorder / Q000188:drug therapy*; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D005260:Female; D005473:Fluoxetine / Q000627:therapeutic use; D006801:Humans; D008094:Lithium / Q000627:therapeutic use*; D008127:Lofepramine / Q000627:therapeutic use*; D008297:Male
D005473:Fluoxetine; D008094:Lithium; D008127:Lofepramine