title: Electrophysiologic findings in optic nerve dysfunction associated with multiple evanescent white-dot syndrome.
abstract: Electrophysiologic findings in a case of multiple evanescent white-dot syndrome were studied. A 37-year-old woman presented with multiple white dots, granularity of the macula, and optic disc swelling in her left fundus. The electroretinogram and electro-oculogram revealed abnormal findings indicative of changes in the retinal pigment epithelium and photoreceptors. In addition, relative afferent pupillary defect, enlargement of the blind spot, a decrease in the critical fusion frequency, staining of the optic disc on fluorescein angiography and prolonged latency of the P100 component with decreased amplitude in pattern-reversal visual evoked cortical potential strongly suggested dysfunction of the optic nerve in this patient.
authors.affiliation: Department of Ophthalmology, Toyama Medical and Pharmaceutical University, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Takeda
authors.forename: K
authors.initials: K
authors.lastname: Numata
authors.forename: S
authors.initials: S
authors.lastname: Yamamoto
authors.forename: T
authors.initials: T
authors.lastname: Katayama
authors.forename: Y
authors.initials: Y
authors.lastname: Kubota
mesh_terms: D000328:Adult; D003623:Dark Adaptation; D004596:Electroretinography; D005074:Evoked Potentials, Visual; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D009901:Optic Nerve Diseases / Q000503:physiopathology*; D010363:Pattern Recognition, Automated; D010775:Photic Stimulation; D010857:Pigment Epithelium of Eye / Q000503:physiopathology*; D012164:Retinal Diseases / Q000503:physiopathology; D013577:Syndrome; D014794:Visual Fields