title: Learning about cancer genes through invertebrate genetics.
abstract: Genetic studies in yeast, nematodes and Drosophila are revealing the signal transduction pathways that regulate differentiation and cell proliferation. Some of the critical molecules involved are homologous to proto-oncogenes and others are likely to be analogous to the products of tumor suppressor genes.
authors.affiliation: McArdle Laboratory for Cancer Research, University of Wisconsin, Madison 53706.
authors.forename: F M
authors.initials: FM
authors.lastname: Hoffmann
authors.forename: P W
authors.initials: PW
authors.lastname: Sternberg
authors.forename: I
authors.initials: I
authors.lastname: Herskowitz
mesh_terms: D000818:Animals; D002107:Caenorhabditis / Q000235:genetics*; D004330:Drosophila / Q000235:genetics*; D009369:Neoplasms / Q000235:genetics*; D015398:Signal Transduction