Inhibition of insulin-stimulated glycogen synthesis in skeletal muscle by resiniferatoxin is probably due to a mechanism involving CGRP.
Leighton
B
B
Department of Biochemistry, University of Oxford, United Kingdom.
Foot
E
E
D000818:Animals; D015740:Calcitonin Gene-Related Peptide / Q000502:physiology*; D002211:Capsaicin / Q000494:pharmacology; D004224:Diterpenes / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D006003:Glycogen / Q000096:biosynthesis*; D007328:Insulin / Q000494:pharmacology*; D007329:Insulin Antagonists / Q000494:pharmacology*; D009132:Muscles / Q000187:drug effects / Q000378:metabolism*; D051381:Rats
D004224:Diterpenes; D007328:Insulin; D007329:Insulin Antagonists; D006003:Glycogen; C024353:resiniferatoxin; D015740:Calcitonin Gene-Related Peptide; D002211:Capsaicin