title: Effects of lasalocid on coccidial infection and growth in young dairy calves.
abstract: Effects of lasalocid on coccidial infection and on calf growth were examined in 16 Holstein bull calves. Calves were assigned randomly to a 2 x 2 factorial arrangement of starter ration containing 0 or 40 mg of lasalocid/kg of starter, beginning when calves were 3 days old (SE = 0.046), and single oral inoculation with 0 or 30,000 sporulated oocysts (Eimeria bovis) at 28 days. Pelleted calf starter was fed ad libitum from day 1; milk replacer was fed at a rate of 3.6 kg/d until day 28. Mean daily gain, dry-matter intake, and body weight were increased in calves fed lasalocid and decreased in those inoculated with coccidia. Addition of lasalocid to the feed improved gains by 8% in uninoculated calves and by 50% in inoculated calves. Fecal oocyst numbers were reduced when lasalocid was fed to inoculated calves. Feces were more abnormal in calves inoculated with coccidia. Respiration rates, rectal temperatures, PCV, and serum sodium and potassium concentrations were unaffected by treatment. On the basis of findings in this study, lasalocid minimized effects of coccidial challenge inoculation and increased growth of calves.
authors.affiliation: Department of Animal Science, University of Tennessee, Knoxville 37901.
authors.forename: G D
authors.initials: GD
authors.lastname: Sinks
authors.forename: J D
authors.initials: JD
authors.lastname: Quigley
authors.forename: C R
authors.initials: CR
authors.lastname: Reinemeyer
mesh_terms: D000821:Animal Feed; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy*; D003048:Coccidiosis / Q000188:drug therapy / Q000662:veterinary*; D003967:Diarrhea / Q000188:drug therapy / Q000662:veterinary; D004435:Eating / Q000187:drug effects; D005243:Feces / Q000469:parasitology; D007832:Lasalocid / Q000494:pharmacology / Q000627:therapeutic use*; D016018:Least-Squares Analysis; D008297:Male; D010270:Parasite Egg Count / Q000662:veterinary; D011897:Random Allocation; D015430:Weight Gain / Q000187:drug effects*
chemical_list: D007832:Lasalocid