Direct projections from the globus pallidus to the midbrain and pons in the cat.
Employing the anterograde and retrograde axonal tracing techniques with Phaseolus vulgaris leucoagglutinin and cholera toxin B subunit, we demonstrated direct projections from the globus pallidus (GP) to the midbrain and pons in the cat. Cells of origin of these projections were localized in the caudal 2/3 of the GP, and their major target sites included the peripeduncular region, nucleus of the brachium of the inferior colliculus, para-lateral lemniscal zone, nucleus sagulum, external and pericentral nuclei of the inferior colliculus, and cuneiform nucleus. A combination of retrograde axonal tracing and immunohistochemistry for choline acetyltransferase revealed that GP neurons giving rise to such descending projections were primarily non-cholinergic.
Shinonaga
Y
Y
Department of Morphological Brain Science, Faculty of Medicine, Kyoto University, Japan.
Takada
M
M
Ogawa-Meguro
R
R
Ikai
Y
Y
Mizuno
N
N
D000818:Animals; D002415:Cats; D002795:Choline O-Acetyltransferase / Q000378:metabolism; D005917:Globus Pallidus / Q000166:cytology / Q000502:physiology*; D007150:Immunohistochemistry; D008636:Mesencephalon / Q000166:cytology / Q000502:physiology*; D009434:Neural Pathways / Q000166:cytology / Q000502:physiology; D010835:Phytohemagglutinins; D011149:Pons / Q000166:cytology / Q000502:physiology*; D013238:Stereotaxic Techniques
D010835:Phytohemagglutinins; C100156:leukoagglutinins, plants; D002795:Choline O-Acetyltransferase