Progressive dystonia with marked diurnal fluctuation.
Two cases of dopa-responsive dystonia with marked diurnal fluctuations are reported. Of these, one was a 26 year old female who had progressive dystonia of more than 20 years' duration with classical diurnal fluctuations exacerbated by exercise and relieved with sleep; she also had significant worsening during menstruation and the later half of her pregnancy, resulting in a stillbirth. She responded remarkably to low doses of L-dopa.
Satishchandra
P
P
Department of Neurology, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore.
Mullati
N
N
Suresh
T G
TG
D000328:Adult; D002648:Child; D002940:Circadian Rhythm; D004421:Dystonia / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*
D007980:Levodopa