title: Calbindin D-28k and parvalbumin immunohistochemistry in developing rat retina.
abstract: The developmental profiles of two calcium-binding proteins, calbindin-D28k (CaBP) and parvalbumin (PV), were investigated immunohistochemically in the developing rat retina. CaBP-immunoreactivity appeared first on embryonic day 17 in the horizontal, amacrine and ganglion cells; on embryonic day 21 in the inner plexiform layer; and on post-natal day 6 in the outer plexiform layer. The reaction intensity had increased to its maximum level by post-natal day 10. PV-immunoreactivity was first noted on embryonic day 19 in the amacrine and ganglion cells and reached its maximum on post-natal day 10. Two distinct subpopulations of amacrine cells were clearly recognized after post-natal day 6; one was positive for CaBP and the other for PV. Some morphological differences were noted between the two.
authors.affiliation: Division of Neurology, University of British Columbia, Vancouver, Canada.
authors.forename: R
authors.initials: R
authors.lastname: Uesugi
authors.forename: M
authors.initials: M
authors.lastname: Yamada
authors.forename: M
authors.initials: M
authors.lastname: Mizuguchi
authors.forename: K G
authors.initials: KG
authors.lastname: Baimbridge
authors.forename: S U
authors.initials: SU
authors.lastname: Kim
mesh_terms: D000818:Animals; D064092:Calbindin 1; D064026:Calbindins; D007150:Immunohistochemistry; D010320:Parvalbumins / Q000032:analysis*; D051381:Rats; D012160:Retina / Q000737:chemistry* / Q000196:embryology / Q000254:growth & development; D012165:Retinal Ganglion Cells / Q000737:chemistry; D064030:S100 Calcium Binding Protein G / Q000032:analysis*; D013997:Time Factors
chemical_list: C576500:Calb1 protein, rat; D064092:Calbindin 1; D064026:Calbindins; D010320:Parvalbumins; D064030:S100 Calcium Binding Protein G