[Contribution of magnesium gluconate in intravenous tocolysis with ritodrine].
The purpose of this randomized study was to compare the efficacy of ritodrine alone (51) versus ritodrine plus magnesium gluconate (56). We concluded that high oral doses of magnesium therapy (4 x 3 gr) potentiate the effects of intravenous beta-agonists, allowing a reduction of the dosage needed and a better "tolerance". Considering the low side effects, it seems reasonable to consider using magnesium in the treatment of premature labour.
Ally
K
K
Département de Gynécologie-Obstétrique, Université de Liège.
Nicolas
A
A
Thoumsin
H
H
Lambotte
R
R
D000284:Administration, Oral; D002985:Clinical Protocols / Q000592:standards*; D004359:Drug Therapy, Combination; D005260:Female; D005942:Gluconates / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D007262:Infusions, Intravenous; D007752:Obstetric Labor, Premature / Q000188:drug therapy*; D011247:Pregnancy; D012312:Ritodrine / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D015145:Tocolysis / Q000379:methods / Q000592:standards*; D014590:Uterine Contraction / Q000187:drug effects / Q000502:physiology
D005942:Gluconates; D012312:Ritodrine; C030691:gluconic acid
Apport du gluconate de magnésium dans la tocolyse parentérale par la ritodrine.