The DDT method: an alternative to the use of radiolabelled microspheres for the determination of regional blood flows in the rat.
Intravenous administration of the 14C-radiolabelled insecticide DDT--1,1,1-trichloro-2,2-bis-(p-chlorophenyl)ethane--can be used for the estimation of regional blood flows in small rodents. A mathematical model is presented which enables the conversion of relative into absolute blood flows.
Argilés
J M
JM
Departament de Bioquímica i Fisiologia, Facultat de Biologia, Universitat de Barcelona, Spain.
Zegrí
A
A
López-Soriano
F J
FJ
D000818:Animals; D003634:DDT / Q000097:blood* / Q000493:pharmacokinetics; D005069:Evaluation Studies as Topic; D006439:Hemodynamics; D051379:Mice; D008863:Microspheres; D008954:Models, Biological; D051381:Rats; D012039:Regional Blood Flow
D003634:DDT