title: Time course EPI of human brain function during task activation.
abstract: Using gradient-echo echo-planar MRI, a local signal increase of 4.3 +/- 0.3% is observed in the human brain during task activation, suggesting a local decrease in blood deoxyhemoglobin concentration and an increase in blood oxygenation. Images highlighting areas of signal enhancement temporally correlated to the task are created.
authors.affiliation: Department of Radiology, Medical College of Wisconsin, Milwaukee 53226.
authors.forename: P A
authors.initials: PA
authors.lastname: Bandettini
authors.forename: E C
authors.initials: EC
authors.lastname: Wong
authors.forename: R S
authors.initials: RS
authors.lastname: Hinks
authors.forename: R S
authors.initials: RS
authors.lastname: Tikofsky
authors.forename: J S
authors.initials: JS
authors.lastname: Hyde
mesh_terms: D001921:Brain / Q000502:physiology*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D013647:Task Performance and Analysis
chemical_list: D006454:Hemoglobins; C100003:deoxyhemoglobin; D010100:Oxygen