title: Antibiotic prophylaxis in neurosurgery. The controlled trials.
abstract: Systemic antibiotics are effective in reducing the risk of infection after clean neurosurgical procedures. They are less effective in preventing shunt infection, but are strongly recommended in institutions experiencing a shunt infection rate exceeding 15%. The role for antibiotic prophylaxis using topical agents and in the prevention of meningitis associated with cerebrospinal fluid drainage is uncertain.
authors.affiliation: Department of Neurosurgery, University of Minnesota Hospital and Clinic, Minneapolis.
authors.forename: S J
authors.initials: SJ
authors.lastname: Haines
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage* / Q000493:pharmacokinetics; D002557:Cerebrospinal Fluid Shunts; D002986:Clinical Trials as Topic / Q000379:methods*; D006801:Humans; D011292:Premedication; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000517:prevention & control*
chemical_list: D000900:Anti-Bacterial Agents