title: Projections from the nucleus accumbens to cholinergic neurons of the ventral pallidum: a correlated light and electron microscopic double-immunolabeling study in rat.
abstract: A correlated light- and electron microscopic double-immunolabeling study combining choline acetyltransferase immunocytochemistry with anterograde tracing of Phaseolus vulgaris leucoagglutinin (PHA-L) revealed that axons of the nucleus accumbens terminate on cholinergic neurons of the ventral pallidum. These findings are discussed with respect to the possibility that these cholinergic neurons may be part of parallel circuits, providing feedback to the same cortical and amygdaloid areas which innervate the nucleus accumbens.
authors.affiliation: Department of Otolaryngology, University of Virginia Health Sciences Center, Charlottesville 22908.
authors.forename: L
authors.initials: L
authors.lastname: Záborszky
authors.forename: W E
authors.initials: WE
authors.lastname: Cullinan
mesh_terms: D000109:Acetylcholine / Q000502:physiology*; D000818:Animals; D002795:Choline O-Acetyltransferase; D005917:Globus Pallidus / Q000648:ultrastructure*; D007124:Immunoenzyme Techniques; D008853:Microscopy; D008854:Microscopy, Electron; D009434:Neural Pathways / Q000648:ultrastructure; D009474:Neurons / Q000648:ultrastructure*; D009714:Nucleus Accumbens / Q000648:ultrastructure*; D010835:Phytohemagglutinins; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D010835:Phytohemagglutinins; C100156:leukoagglutinins, plants; D002795:Choline O-Acetyltransferase; D000109:Acetylcholine