title: DES clinic--the first six months.
abstract: In October 1990 a DES (Diethylstilbestrol) clinic was established at the National Maternity Hospital, Dublin. We describe the results of the first six months of the clinic. During this time, 172 inquiries were received; 95 women were seen at the clinic, 16 were deemed to be DES--exposed and eight were classified as possibly DES exposed. Classical cervicovaginal signs of DES exposure were noted in 15 women, a further eight women showed cervical epithelial abnormalities at colposcopy, the history of in utero DES exposure was confirmed in eight cases. No cases of cervical intraepithelial neoplasia or vaginal clear-cell adenocarcinoma were detected. Pregnancy related problems possibly attributable to DES exposure were documented in six women.
authors.affiliation: National Maternity Hospital, Dublin.
authors.forename: M
authors.initials: M
authors.lastname: Wingfield
authors.forename: V S
authors.initials: VS
authors.lastname: Donnelly
authors.forename: P
authors.initials: P
authors.lastname: Kelehan
authors.forename: J M
authors.initials: JM
authors.lastname: Stronge
authors.forename: J
authors.initials: J
authors.lastname: Murphy
authors.forename: P
authors.initials: P
authors.lastname: Boylan
mesh_terms: D000230:Adenocarcinoma / Q000139:chemically induced; D000293:Adolescent; D000328:Adult; D004054:Diethylstilbestrol / Q000009:adverse effects*; D005260:Female; D006771:Hospitals, Maternity / Q000706:statistics & numerical data; D006801:Humans; D007494:Ireland; D010044:Outpatient Clinics, Hospital / Q000458:organization & administration / Q000706:statistics & numerical data*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D002583:Uterine Cervical Neoplasms / Q000139:chemically induced
chemical_list: D004054:Diethylstilbestrol