Spontaneous visual improvement in chiasmal gliomas.
Three untreated patients with presumed chiasmal gliomas had spontaneous visual improvement, although serial magnetic resonance imaging in two of the patients showed the lesions to be unchanged. Two patients had evidence of neurofibromatosis. Three other patients with similar disease courses have been documented in the medical literature. These cases demonstrate that conservative management of optic chiasmal gliomas may sometimes be associated with favorable outcomes.
Liu
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Harvard-Longwood Neurology Program, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston.
Lessell
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S
D000293:Adolescent; D000328:Adult; D002648:Child; D003390:Cranial Nerve Neoplasms / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D005260:Female; D005500:Follow-Up Studies; D005910:Glioma / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009897:Optic Chiasm / Q000503:physiopathology*; D012075:Remission, Spontaneous; D014786:Vision Disorders / Q000209:etiology / Q000503:physiopathology*; D014792:Visual Acuity; D014794:Visual Fields