[Effect of histological criteria (TpNM classification, degree of differentiation) on mortality of patients with retinoblastoma].
153 patients suffering from retinoblastoma and treated between 1960 and 1980 were analysed retrospectively. Median follow-up was 11.2 years. 13 patients (8.5%) died from retinoblastoma. 3 patients died from a secondary osteosarcoma. The survival rates from patients with differentiated retinoblastomas did not differ from those with undifferentiated tumor cells. Optic nerve invasion decreased significantly the survival rate and involvement of the sectional line led to a survival rate after 5 years of only 22.2%. Due to 3 cases of death from secondary osteosarcoma, the survival rate of 91.14% after 5 years deteriorated to 87.64% after 10 to 14 years.
Lommatzsch
P K
PK
Augenklinik, Universität Leipzig.
Morgenstern
B
B
D002648:Child; D002675:Child, Preschool; D005134:Eye Neoplasms / Q000401:mortality* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D009367:Neoplasm Staging; D012160:Retina / Q000473:pathology; D012175:Retinoblastoma / Q000401:mortality* / Q000473:pathology; D015996:Survival Rate
Der Einfluss histologischer Kriterien (TpNM-Klassifikation, Differenzierungsgrad) auf die Letalität von Patienten mit Retinoblastom.