[Morphological comparison between pm-carcinoma and minute ss-carcinoma of the gallbladder].
Eleven cases of pm-carcinoma and thirty cases of minute ss-carcinoma of the gallbladder were compared with their morphologies and biological behavior with reference to the assessment of pm-carcinoma as early carcinoma. The vascular permeation and lymph nodal metastasis was 9% and 0%, respectively, in the pm-carcinoma and 43% and 9% in the minute ss-carcinoma. The 5-year survival rate of the pm-carcinoma was better (100%) than the minute ss-carcinoma (73.3%). The poorly differentiated adenocarcinoma or well differentiated adenocarcinoma with high grade atypia in the invasive-area was higher in incidence in the minute ss-carcinoma. From these findings it is concluded that the pm-carcinoma should be defined as early carcinoma in the gallbladder. The both carcinomas were hardly distinguishable macroscopically. Therefore, the careful examination of resected gallbladder by stepwise sections is important.
Katayama
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Fourth Department of Internal Medicine, Tokyo Medical College.
D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology*; D000368:Aged; D005706:Gallbladder Neoplasms / Q000401:mortality / Q000473:pathology*; D006801:Humans; D008207:Lymphatic Metastasis; D009361:Neoplasm Invasiveness; D015996:Survival Rate