[Local recurrence of differentiated thyroid carcinoma effectively treated by local injection of OK-432].
Local recurrence of differentiated thyroid carcinoma in a 67-year-old woman was treated by topical injection of OK-432 every 2-4 weeks. Recurrent tumors turned into small scar-like tissues after 9 months of OK-432 administration. The bleeding from the tumor was well controlled. Secondary recurrent tumors were also effectively treated in the same manner. About 2 years have passed since the start of the treatment and the local recurrence is well controlled. We conclude that topical injection of OK-432 might be a good modality of treatment for the local recurrence of thyroid carcinoma.
Kato
R
R
Department of Surgery, School of Medicine, Keio University, Tokyo, Japan.
Kobayashi
T
T
Watanabe
M
M
Kawamura
M
M
Kikuchi
K
K
Kobayashi
K
K
Ishihara
T
T
D002277:Carcinoma / Q000628:therapy*; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000628:therapy*; D010844:Picibanil / Q000008:administration & dosage / Q000627:therapeutic use*; D012074:Remission Induction; D013964:Thyroid Neoplasms / Q000628:therapy*
D010844:Picibanil