title: Segregation of three reciprocal translocations in the same family: t(3;4), t(5;10), and t(15;21).
abstract: A male infant with static antenatal encephalopathy and epilepsy was found to have a duplication of 5p12----5pter and deficiency of 10p13----10pter. Each of his parents was a carrier of a balanced reciprocal translocation. A third translocation was found in the maternal grandfather. The pedigree of each translocation and the segregation of parental reciprocal translocations are discussed.
authors.affiliation: Service d'Histologie-Embryologie-Cytogénétique et Anatomie Pathologique, Hôpital Saint-Vincent de Paul, Paris, France.
authors.forename: L
authors.initials: L
authors.lastname: Telvi
authors.forename: M
authors.initials: M
authors.lastname: Folhen
authors.forename: O
authors.initials: O
authors.lastname: Raoul
authors.forename: J
authors.initials: J
authors.lastname: Feingold
authors.forename: G
authors.initials: G
authors.lastname: Ponsot
authors.forename: A
authors.initials: A
authors.lastname: Pompidou
authors.forename: M O
authors.initials: MO
authors.lastname: Rethoré
authors.forename: J
authors.initials: J
authors.lastname: Lejeune
mesh_terms: D000596:Amino Acids / Q000032:analysis; D001927:Brain Diseases / Q000196:embryology / Q000235:genetics*; D002872:Chromosome Deletion; D002879:Chromosomes, Human, Pair 10; D002895:Chromosomes, Human, Pair 5; D004827:Epilepsy / Q000235:genetics*; D006580:Genetic Carrier Screening; D006801:Humans; D007223:Infant; D007621:Karyotyping; D008297:Male; D005810:Multigene Family / Q000235:genetics; D010375:Pedigree; D014178:Translocation, Genetic / Q000235:genetics*
chemical_list: D000596:Amino Acids