Study of the gastrointestinal diffusion system (GDS): influence of acacia gum on mechanical and chemical properties in free cellulose acetate films.
In this work a study of free cellulose acetate films was carried out in the presence and absence of acacia gum at high concentrations (50 and 75%). The mechanical toughness and the aspect were influenced by operatory conditions and by the relative air humidity. The increase of relative humidity from about 0% to 75% decreased the mechanical toughness and the color film changed from a clear to opaque white. The presence of acacia gum decreased the mechanical toughness and the water vapour transmission rate and increased the film water solubility.
Mahieux
P
P
Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Paris, France.
Arnaud
P
P
Chaumeil
J C
JC
D002482:Cellulose / Q000031:analogs & derivatives* / Q000737:chemistry; D003692:Delayed-Action Preparations; D004058:Diffusion; D006170:Gum Arabic / Q000737:chemistry*; D008567:Membranes, Artificial; D010539:Permeability; D012212:Rheology; D013718:Tensile Strength; D014867:Water / Q000737:chemistry
D003692:Delayed-Action Preparations; D008567:Membranes, Artificial; D014867:Water; C005062:acetylcellulose; D006170:Gum Arabic; D002482:Cellulose