title: Role of soluble factors in immune and normal sera in the control of giardiasis due to Giardia lamblia.
abstract: Hyperimmune sera (HIS), raised against crude giardia antigen, on in vitro interaction, caused more agglutination of Giardia lamblia trophozoites. Heat inactivated HIS possessed a comparable agglutinating activity as the non-inactivated controls. Non-inactivated normal (unimmunized) serum caused immobilization of Giardia trophozoite, which was checked on heat inactivation. Antibodies in immune sera are mainly responsible for agglutination, whereas the heat labile non-immune components control the mobility of the intestinal parasite.
authors.affiliation: Division of Toxicology, Central Drug Research Institute, Lucknow, India.
authors.forename: R K
authors.initials: RK
authors.lastname: Srivastava
authors.forename: N
authors.initials: N
authors.lastname: Sethi
authors.forename: N
authors.initials: N
authors.lastname: Gupta
authors.forename: A K
authors.initials: AK
authors.lastname: Agarwal
mesh_terms: D000371:Agglutination; D000818:Animals; D004306:Dose-Response Relationship, Immunologic; D016829:Giardia lamblia / Q000276:immunology* / Q000502:physiology; D005873:Giardiasis / Q000097:blood / Q000276:immunology*; D007106:Immune Sera / Q000276:immunology*; D011817:Rabbits
chemical_list: D007106:Immune Sera