Neurological complications after thrombolytic treatment for acute myocardial infarction: emphasis on unprecedented manifestations.
We examined 348 patients who underwent thrombolytic treatment for acute myocardial infarction. Nine patients (2.58%) developed neurological complications related directly or indirectly to this procedure. Cerebral hemorrhage occurred in 3 patients; 2 patients had transient ischemic attacks, 1 had syncope, another had psychomotor agitation and 2 patients presented seizures during the infusion of the thrombolytic agent, without hemodynamic abnormalities. This latter feature had never been described before.
Caramelli
P
P
Department of Neurology, University of São Paulo, Brazil.
Mutarelli
E G
EG
Caramelli
B
B
Tranchesi
B
B
Pileggi
F
F
Scaff
M
M
D000328:Adult; D001927:Brain Diseases / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D002561:Cerebrovascular Disorders / Q000188:drug therapy / Q000209:etiology; D004789:Enzyme Activation; D005260:Female; D005343:Fibrinolytic Agents; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D010672:Phenytoin / Q000627:therapeutic use; D012640:Seizures / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage
D005343:Fibrinolytic Agents; D010672:Phenytoin; D006493:Heparin; D010959:Tissue Plasminogen Activator