title: Aging and humoral immunity.
abstract: If human antibody responses undergo molecular shifts similar to those identified in mice, the appropriate immunization strategy for the elderly would be a passive administration of the protective antibody from young donors rather than an attempt to boost the individual's own response with a more potent vaccine, because the shifted immune system can no longer make the right kind of antibody.
authors.affiliation: Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore 21201.
authors.forename: E A
authors.initials: EA
authors.lastname: Goidl
authors.forename: J
authors.initials: J
authors.lastname: Cerny
authors.forename: G
authors.initials: G
authors.lastname: Kelsoe
authors.forename: D H
authors.initials: DH
authors.lastname: Schulze
mesh_terms: D000375:Aging / Q000276:immunology*; D000818:Animals; D000917:Antibody Formation; D006801:Humans