title: Familial pulmonary nodular lymphoid hyperplasia.
abstract: We describe three persons in one family with diffuse lung infiltrates, digital clubbing, and chronic hypoxia. Elevated immunoglobulin levels and antinuclear antibodies were found in all patients; pathologic findings included hyperplastic lymphoid follicles infiltrating the epithelium of the small airways. These cases may represent a familial systemic autoimmune disorder seen primarily with pulmonary compromise.
authors.affiliation: Pediatric Pulmonary and Critical Care Division, Memorial Miller Children's Hospital, Long Beach, CA 90801.
authors.forename: L M
authors.initials: LM
authors.lastname: Franchi
authors.forename: T W
authors.initials: TW
authors.lastname: Chin
authors.forename: E
authors.initials: E
authors.lastname: Nussbaum
authors.forename: J
authors.initials: J
authors.lastname: Riker
authors.forename: M
authors.initials: M
authors.lastname: Robert
authors.forename: W M
authors.initials: WM
authors.lastname: Talbert
mesh_terms: D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D001327:Autoimmune Diseases / Q000235:genetics* / Q000473:pathology; D003490:Cyanosis / Q000473:pathology; D005260:Female; D005385:Fingers / Q000473:pathology; D006801:Humans; D006965:Hyperplasia; D007074:Immunoglobulin G / Q000032:analysis; D007223:Infant; D008171:Lung Diseases / Q000235:genetics* / Q000473:pathology; D008221:Lymphoid Tissue / Q000473:pathology*; D008297:Male; D011658:Pulmonary Fibrosis / Q000473:pathology
chemical_list: D000974:Antibodies, Antinuclear; D007074:Immunoglobulin G