title: TORCH infections. Diagnosis in the molecular age.
abstract: TORCH agents cause a varied spectrum of disease. Advances in ultrasound, invasive perinatal procedures and molecular diagnostics have allowed in utero evaluation. Infected fetuses, especially those which are sonographically abnormal, may be treated in utero depending upon the pathogen and attendant pathophysiology. Subclinical perinatal infections may lead to later childhood deficits. Such infected fetuses may benefit from early diagnosis and prompt initiation of rehabilitative measures.
authors.affiliation: Department of Obstetrics and Gynecology, Hutzel Hospital, Wayne State University, Detroit.
authors.forename: N B
authors.initials: NB
authors.lastname: Isada
authors.forename: D P
authors.initials: DP
authors.lastname: Paar
authors.forename: J H
authors.initials: JH
authors.lastname: Grossman
authors.forename: S E
authors.initials: SE
authors.lastname: Straus
mesh_terms: D000004:Abbreviations as Topic; D000649:Amniocentesis; D015342:DNA Probes; D005260:Female; D005312:Fetal Blood / Q000737:chemistry / Q000382:microbiology; D005315:Fetal Diseases / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D007231:Infant, Newborn; D007239:Infections / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology; D008403:Mass Screening / Q000379:methods / Q000592:standards; D008967:Molecular Biology / Q000379:methods* / Q000592:standards; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods* / Q000592:standards; D016216:Ultrasonography, Prenatal
chemical_list: D015342:DNA Probes