title: [Effects of callosotomy in the treatment of intractable epilepsies in children on psychiatric disorders].
abstract: Two children, 13 and 14 years old, presented an intractable epilepsy of Lennox-Gastaut. In front of dangerous tonic and atonic epileptic crisis, a corpus callosotomy was performed. Corpus callosotomy is becoming a more widely used procedure in the treatment of intractable epilepsy as Lennox-Gastaut syndrome, or frontal epilepsy. However, there have been very few series that have reported results in children. It is not a complete but a partial, callosal section including approximately the anterior two thirds of the callosum. After this surgery the two children improved dramatically because the dangerous tonic and atonic crisis disappeared. Secondly we observed improvement of pre-surgical psychiatric troubles, that is a data not developed in the literature. Before surgery, the two children had a frontal syndrome with hyperkinesia, distractibility, aggressiveness, alexithymia, loss of the program of ideas. During the two months after the section of the anterior two thirds of the corpus callosum, we observed a progressive improvement of the frontal syndrome, with possibility to learn new praxies. The intellectual quotient was not altered and associative functions, depending of the posterior third of the corpus callosum were spared. Anti-epileptic medications were not stopped. We think that the improvement of the frontal syndrome is due to reduction of seizures. Therefore, we insist on the interest of the section of the anterior two thirds of the corpus callosum as treatment of tonic and atonic seizures but also as treatment of psychiatric symptoms depending of a frontal syndrome.
authors.affiliation: Service de Pédiatrie, Hôpital d'Enfants, Dijon.
authors.forename: L
authors.initials: L
authors.lastname: Septien
authors.forename: M
authors.initials: M
authors.lastname: Giroud
authors.forename: J L
authors.initials: JL
authors.lastname: Sautreaux
authors.forename: M
authors.initials: M
authors.lastname: Brenot
authors.forename: A
authors.initials: A
authors.lastname: Marin
authors.forename: R
authors.initials: R
authors.lastname: Dumas
authors.forename: J L
authors.initials: JL
authors.lastname: Nivelon
mesh_terms: D000293:Adolescent; D003337:Corpus Callosum / Q000601:surgery*; D017034:Epilepsy, Frontal Lobe / Q000209:etiology / Q000601:surgery*; D004830:Epilepsy, Tonic-Clonic / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D010556:Personality Tests; D011594:Psychometrics; D011612:Psychosurgery / Q000379:methods*; D011618:Psychotic Disorders / Q000601:surgery*
vernacular_title: Les effets de la callosotomie dans le traitement de l'épilepsie rebelle de l'enfant sur les troubles psychiques.