title: Successful treatment of a hepatic cyst by one-shot instillation of minocycline chloride.
abstract: Hepatic cysts are not rare but usually are asymptomatic; however, large ones sometimes show clinical manifestations. Treatment of a solitary hepatic cyst by one-shot instillation of minocycline chloride is reported here; 500 mg of minocycline chloride was instilled into the hepatic cyst, 11 cm in diameter, through a percutaneous transhepatic cholangiography needle under ultrasound guidance. After 5 weeks, the cyst had decreased in size to 5 cm. Five months later, the cyst could not be detected by diagnostic imaging. Fifteen months after the treatment, no reaccumulated fluid was observed. Ultrasound-guided percutaneous one-shot instillation of minocycline chloride seems to be a safe, easy, and useful procedure for treating a hepatic cyst.
authors.affiliation: First Department of Medicine, Osaka University Medical School, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Hagiwara
authors.forename: A
authors.initials: A
authors.lastname: Kasahara
authors.forename: N
authors.initials: N
authors.lastname: Hayashi
authors.forename: M
authors.initials: M
authors.lastname: Kono
authors.forename: K
authors.initials: K
authors.lastname: Suzuki
authors.forename: S
authors.initials: S
authors.lastname: Kashio
authors.forename: H
authors.initials: H
authors.lastname: Fusamoto
authors.forename: T
authors.initials: T
authors.lastname: Kamada
mesh_terms: D003560:Cysts / Q000188:drug therapy*; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D008107:Liver Diseases / Q000188:drug therapy*; D008875:Middle Aged; D008911:Minocycline / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D008911:Minocycline