title: Absence of colorectal cancer metastasis to the cirrhotic liver.
abstract: Hepatic metastasis of colorectal cancer was found in 40 (16%) of 250 patients with colorectal cancer treated in our department during the past 5 years. Liver cirrhosis was not found among the 40 patients with metastases (16%) but was present in 46 (21.9%) of the 210 nonmetastatic patients, with a significant difference between the two groups (p less than 0.001). The rate of patients who were positive for hepatitis B surface antibody was 10% in the metastatic group and 34.3% in the nonmetastatic group, with a significant difference (p less than 0.01). These findings suggest that colorectal cancer does not metastasize to the injured liver, especially the cirrhotic liver.
authors.affiliation: Department of Surgery, Kansai Medical University, Moriguchi City, Osaka, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Uetsuji
authors.forename: M
authors.initials: M
authors.lastname: Yamamura
authors.forename: K
authors.initials: K
authors.lastname: Yamamichi
authors.forename: Y
authors.initials: Y
authors.lastname: Okuda
authors.forename: H
authors.initials: H
authors.lastname: Takada
authors.forename: K
authors.initials: K
authors.lastname: Hioki
mesh_terms: D015179:Colorectal Neoplasms / Q000401:mortality; D005260:Female; D006498:Hepatectomy; D006801:Humans; D015994:Incidence; D008103:Liver Cirrhosis / Q000453:epidemiology; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery; D008297:Male