title: Blood zinc status and zinc treatment in human immunodeficiency virus-infected patients.
abstract: We investigated the zinc concentration in blood and the effect of zinc supplementation in 11 male outpatients seropositive for human immunodeficiency virus at stage 5 according to the Walter Reed classification. Zinc concentration was measured in serum, platelets, mononuclear and polymorphonuclear cells, and erythrocytes. There was a significant increase in serum zinc concentration after zinc administration, but the zinc level in blood cells remained unchanged. All patients showed a progressive gain in body weight and a slight elevation in levels of CD4+ cells. No adverse side-effects were noticed.
authors.affiliation: Division of Medicine, Gorgonzola-Melzo Hospital, Milan, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Isa
authors.forename: A
authors.initials: A
authors.lastname: Lucchini
authors.forename: S
authors.initials: S
authors.lastname: Lodi
authors.forename: M
authors.initials: M
authors.lastname: Giachetti
mesh_terms: D000293:Adolescent; D000328:Adult; D001835:Body Weight / Q000187:drug effects; D015658:HIV Infections / Q000097:blood / Q000188:drug therapy*; D006801:Humans; D008297:Male; D015032:Zinc / Q000097:blood / Q000627:therapeutic use*
chemical_list: D015032:Zinc