title: Radiation therapy for skin cancer near the eye: kilovoltage x-rays versus electrons.
abstract: When skin cancer near the eye is irradiated, a corneal shield is placed between the lids and globe to protect ocular structures. The effectiveness of the shield was evaluated with 250 kVp x-ray and 6-20 MeV electron beams. To simulate the clinical situation, a face phantom was constructed out of solid pieces of water-equivalent epoxy. In the region of the eye the phantom was milled to the exact contour of a human face. The phantom was used to reconstruct the setup that had been used to treat a patient with a 1-cm basal cell carcinoma of the mid portion of the lower lid. A medium-sized corneal shield (2-mm-thick lead plated with 0.1 mm gold) was placed on the eye portion of the phantom. A contoured lead (6 mm thick) face mask was placed on the surface of the phantom to define a 3-cm diameter radiation field that included only the inferior hemisphere of the shield. The doses that the cornea, lens, and retina would receive beneath the midpoint of the inferior hemisphere of the shield were measured using thermoluminescent and film dosimetry. With 6 to 8 MeV electrons, the corneal dose was 2 to 4 times higher than with 250 kVp x-rays. Corneal and lens doses rose rapidly with increasing electron beam energy such that with greater than 8 MeV the shield would provide relatively poor ocular protection. A scanning ion chamber and film dosimetry were used to determine the isodose profiles of 250 kVp x-ray and 6 MeV electron beams for a 3-cm diameter field collimated on the surface. With 250 kVp x-rays the 95% isodose area was 32% wider than with 6 MeV electrons. The ease of shielding and the ability to minimize field size argue in favor of kilovoltage x-rays for early-stage skin cancer near the eye.
authors.affiliation: Department of Radiation Oncology, University of Florida College of Medicine, Gainesville.
authors.forename: R J
authors.initials: RJ
authors.lastname: Amdur
authors.forename: K J
authors.initials: KJ
authors.lastname: Kalbaugh
authors.forename: L M
authors.initials: LM
authors.lastname: Ewald
authors.forename: J T
authors.initials: JT
authors.lastname: Parsons
authors.forename: W M
authors.initials: WM
authors.lastname: Mendenhall
authors.forename: F J
authors.initials: FJ
authors.lastname: Bova
authors.forename: R R
authors.initials: RR
authors.lastname: Million
mesh_terms: D003365:Costs and Cost Analysis; D004583:Electrons; D005131:Eye Injuries / Q000517:prevention & control*; D006801:Humans; D008961:Models, Structural; D011829:Radiation Dosage; D011832:Radiation Injuries / Q000517:prevention & control*; D011835:Radiation Protection / Q000295:instrumentation*; D011882:Radiotherapy, High-Energy / Q000191:economics; D012878:Skin Neoplasms / Q000532:radiotherapy*