The effect of sodium cromoglycate eyedrops compared to the effect of terfenadine on acute symptoms of seasonal allergic conjunctivitis.
A multicentre, group comparative open study was carried out on 68 patients to compare the effects of 2% sodium cromoglycate eyedrops and an oral antihistamine, terfenadine, on acute symptoms of seasonal allergic conjunctivitis. The study was continued for one week after the onset of acute symptoms. Both medications were equally efficient in reducing symptoms during the first hour of observation. During the one-week follow-up both medications reduced symptoms to a low level, and both medications were equally effective for allergic symptoms, except that terfenadine was more effective in reducing the watering of eyes.
Leino
M
M
Department of Ophthalmology, University Hospital of Kuopio, Finland.
Carlson
C
C
Kilkku
O
O
Kumpulainen
T
T
Kyrönpalo-Kauppinen
S
S
Laaka
V
V
Norio
M
M
Valtola
J
J
D000208:Acute Disease; D000284:Administration, Oral; D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003233:Conjunctivitis, Allergic / Q000188:drug therapy*; D004205:Cromolyn Sodium / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D010342:Patient Acceptance of Health Care; D012621:Seasons; D016593:Terfenadine / Q000009:adverse effects / Q000627:therapeutic use*
D016593:Terfenadine; D004205:Cromolyn Sodium