title: Anaphylaxis.
abstract: The syndrome of anaphylaxis is a life-threatening event in which the potential for patient morbidity and mortality is high. An understanding of the pathophysiology of anaphylaxis, the most serious of the allergic disorders, is paramount for its diagnosis. In addition to these elements, this article discusses newly recognized causes of anaphylaxis and reviews its treatment.
authors.affiliation: Laboratory of Clinical Investigation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
authors.forename: T P
authors.initials: TP
authors.lastname: Atkinson
authors.forename: M A
authors.initials: MA
authors.lastname: Kaliner
mesh_terms: D000707:Anaphylaxis / Q000175:diagnosis / Q000276:immunology / Q000628:therapy; D016887:Cardiopulmonary Resuscitation / Q000379:methods; D002927:Cimetidine / Q000627:therapeutic use; D002985:Clinical Protocols / Q000592:standards; D003167:Complement Activation / Q000276:immunology; D003937:Diagnosis, Differential; D004155:Diphenhydramine / Q000627:therapeutic use; D004632:Emergency Medical Services; D004837:Epinephrine / Q000627:therapeutic use; D006801:Humans; D008407:Mast Cells / Q000276:immunology
chemical_list: D002927:Cimetidine; D004155:Diphenhydramine; D004837:Epinephrine