Influence of verapamil on the coronary arteriovenous difference in long chain free fatty acids in hypertrophic cardiomyopathy.
The percentage composition of free fatty acids in the coronary circulation has been studied during the passage of blood through the heart in patients with hypertrophic cardiomyopathy. Under basal conditions the percentages of palmitic and stearic acid decreased significantly. Verapamil i.v. produced a tendency towards a preferential myocardial uptake of oleic acid.
Dubiel
J S
JS
II. Department of Cardiology, Nicolas Copernicus Medical School, Cracow, Poland.
Jaśkiewicz
J
J
Zmudka
K
K
Brzostek
T
T
Surdacki
A
A
D000328:Adult; D002312:Cardiomyopathy, Hypertrophic / Q000097:blood* / Q000378:metabolism; D003326:Coronary Circulation; D003331:Coronary Vessels; D005230:Fatty Acids, Nonesterified / Q000097:blood* / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000378:metabolism*; D019301:Oleic Acid; D009829:Oleic Acids / Q000097:blood / Q000378:metabolism; D019308:Palmitic Acid; D010169:Palmitic Acids / Q000097:blood / Q000378:metabolism; D014700:Verapamil / Q000494:pharmacology*
D005230:Fatty Acids, Nonesterified; D009829:Oleic Acids; D010169:Palmitic Acids; D019301:Oleic Acid; D019308:Palmitic Acid; D014700:Verapamil