Leukemic pneumonitis as a poor prognostic factor in chronic myelomonocytic leukemia.
We report the case of a 69-year-old man with chronic myelomonocytic leukemia (CMML) that was complicated by fatal respiratory failure. Bilateral pulmonary infiltrates were demonstrated by chest roentgenograms and worsened with an increase in the leukocyte count. Postmortem examination confirmed the presence of leukemic monocyte infiltration of the pulmonary interstitial spaces. In CMML with marked monocytosis, respiratory failure may be one of the important causes of death in addition to infection and bleeding.
Yamauchi
K
K
Department of Internal Medicine, Tokai University School of Medicine, Kanagawa, Japan.
Omata
T
T
D000368:Aged; D006801:Humans; D015477:Leukemia, Myelomonocytic, Chronic / Q000097:blood / Q000150:complications*; D007958:Leukocyte Count; D008297:Male; D011379:Prognosis; D011658:Pulmonary Fibrosis / Q000209:etiology* / Q000473:pathology