title: White blood cell immunization and anticardiolipin antibody levels in women with recurrent miscarriages.
abstract: To determine whether WBC immunization stimulates production of anticardiolipin antibodies, anticardiolipin antibodies were measured before and 6 weeks after WBC immunization. Twenty-four non-pregnant women, who had had recurrent miscarriages for which a definitive cause could not be determined, were immunized with their partner's WBC. No significant differences in levels of anticardiolipin antibodies were detected between paired samples of sera obtained before and 6 weeks after WBC immunization. White cell immunization in nonpregnant women did not stimulate production of anticardiolipin antibodies.
authors.affiliation: Foundation for Blood Research, Scarborough, Maine 04070-0190.
authors.forename: R A
authors.initials: RA
authors.lastname: Doherty
authors.forename: P
authors.initials: P
authors.lastname: Stubblefield
authors.forename: D A
authors.initials: DA
authors.lastname: Dostal-Johnson
authors.forename: G J
authors.initials: GJ
authors.lastname: Day
mesh_terms: D000026:Abortion, Habitual / Q000097:blood / Q000276:immunology*; D000906:Antibodies / Q000032:analysis; D002308:Cardiolipins / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007114:Immunization; D007075:Immunoglobulin M / Q000032:analysis; D007962:Leukocytes / Q000276:immunology*; D011247:Pregnancy
chemical_list: D000906:Antibodies; D002308:Cardiolipins; D007075:Immunoglobulin M