[The appearance of "central core of respiratory muscle" in patients with respiratory failure].
We report the histological and histochemical features of core fibers present in respiratory muscles obtained from autopsy since 1980. Fifty autopsy cases of adults without neuromuscular disease were examined. "Central core" structure was present in 38 cases and absent in 12 cases. The duration of D.O.E. was greater than 1 month in 81.8% of core positive cases. In core negative cases, the duration of D.O.E. was less than 3 months. "Central core" structure were present in 80.0% of chronic respiratory failure cases and 41.7% of non-chronic cases. It is suggested that central core in respiratory muscles develops less than 3 months after the onset of D.O.E.
Nozaki
H
H
Department of Internal Medicine, National Higashi-Saitama Hospital, Japan.
Ishihara
T
T
Takashima
S
S
Urano
T
T
Toyoda
T
T
Aoyagi
T
T
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003964:Diaphragm / Q000473:pathology; D004417:Dyspnea / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012131:Respiratory Insufficiency / Q000473:pathology*; D012132:Respiratory Muscles / Q000473:pathology*