[The expression of hetero-organic antigens of kidney origin on the surfaces of cultured rat hepatocytes under the influence of the narrow-band fractions of non-histone chromosomal proteins].
Narrow fractions of nonhistone chromosomal proteins (NHCP) eluted with 0.4-0.5 M NaCl from the phosphocellulose column stimulate expression of hetero-organic antigens of kidney origin on the membrane of intact hepatocytes cultured in suspension. These fractions of NHCP were isolated from the intact rats kidney, from cells of hepatoma 27 and Zajdela hepatoma, and from the carcinogenic liver after a single diethylnirozamine injection. The membrane hetero-organic antigens were identified by means of indirect immunofluorescence using specific immune serum.
Ivanov
V A
VA
Fedorov
L Iu
LIu
Grandilevskaia
A B
AB
Klimova
A A
AA
Kushner
V P
VP
Fel'
V Ia
VIa
D000818:Animals; D015478:Antigens, Heterophile / Q000032:analysis / Q000187:drug effects*; D000951:Antigens, Neoplasm / Q000032:analysis / Q000187:drug effects; D000954:Antigens, Surface / Q000032:analysis / Q000187:drug effects; D002478:Cells, Cultured / Q000187:drug effects / Q000276:immunology; D002868:Chromosomal Proteins, Non-Histone / Q000302:isolation & purification / Q000494:pharmacology*; D004052:Diethylnitrosamine / Q000494:pharmacology; D007668:Kidney / Q000166:cytology / Q000187:drug effects / Q000276:immunology*; D008099:Liver / Q000166:cytology / Q000187:drug effects / Q000276:immunology*; D008114:Liver Neoplasms, Experimental / Q000276:immunology; D008297:Male; D051381:Rats; D012208:Rhabdomyosarcoma / Q000276:immunology; D014407:Tumor Cells, Cultured / Q000187:drug effects / Q000276:immunology
D015478:Antigens, Heterophile; D000951:Antigens, Neoplasm; D000954:Antigens, Surface; D002868:Chromosomal Proteins, Non-Histone; D004052:Diethylnitrosamine
Ekspressiia geteroorgannykh antigenov pochechnoĭ prirody na poverkhnosti kul'tiviruemykh gepatotsitov krys pod vliianiem uzkikh fraktsiĭ khromosomal'nykh negistonovykh belkov.