Sporeamicin A, a new macrolide antibiotic. II. Structure determination.
Structure of a novel antibiotic, sporeamicin A (SRM-A), was determined by a combination of spectroscopic and X-ray crystallographic studies. SRM-A has a unique structure containing a 2,3-dihydro-3-oxofuran moiety as part of a 14-membered macrolide ring.
Morishita
A
A
Research Laboratories, Toyo Jozo Co., Ltd., Shizuoka, Japan.
Ishizawa
K
K
Mutoh
N
N
Yamamoto
T
T
Hayashi
M
M
Yaginuma
S
S
D000900:Anti-Bacterial Agents / Q000737:chemistry*; D004917:Erythromycin / Q000031:analogs & derivatives* / Q000737:chemistry; D014961:X-Ray Diffraction
D000900:Anti-Bacterial Agents; C075534:sporeamicin A; D004917:Erythromycin