IgA producing primary intracerebral lymphoma.
The first case of a primary and solitary IgA (lambda) producing tumour (possibly a non-Hodgkin's lymphoma) in the CNS is reported. Clinical and neuroimaging findings are described. Early diagnosis without brain biopsy and successful therapy were possible by CSF and serum immunoglobulin analysis which proved local paraprotein production restricted to the CNS.
Burkhardt
D
D
Department of Neurology, University of Goettingen, Germany.
Schipper
H I
HI
Kaboth
U
U
Felgenhauer
K
K
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000134:cerebrospinal fluid*; D007146:Immunoglobulin lambda-Chains / Q000134:cerebrospinal fluid*; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy; D014057:Tomography, X-Ray Computed
D000305:Adrenal Cortex Hormones; D007070:Immunoglobulin A; D007146:Immunoglobulin lambda-Chains