title: [Creutzfeldt-Jakob disease. The first case with histopathological study in Panama].
abstract: We studied the clinical and histopathology findings of the first proved case of Creutzfeldt-Jakob disease in Panama. A sixty-five-years-old female patient referred from Santiago de Veraguas was admitted to Santo Tomás Hospital with a progressive clinical picture of dementia, incoordination and generalized myoclonia. The electroencephalogram showed periodic paroxysmal activity. The patient died eight months after initiated the disease. The cerebral histopathologic study was characteristic of Creutzfeldt-Jakob disease: status spongiform, neuronal loss and non-inflammatory gliosis was found.
authors.affiliation: Sección de Neurología, Hospital Santo Tomás, Panama.
authors.forename: F
authors.initials: F
authors.lastname: Gracia
authors.forename: R
authors.initials: R
authors.lastname: Díaz
authors.forename: M
authors.initials: M
authors.lastname: Larreátegui
authors.forename: L
authors.initials: L
authors.lastname: Castillo
mesh_terms: D000368:Aged; D002525:Cerebellar Cortex / Q000473:pathology; D002540:Cerebral Cortex / Q000473:pathology; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis / Q000473:pathology*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D010176:Panama
vernacular_title: Enfermedad de Creutzfeldt-Jakob. Primer caso con estudio histopatológico en Panamá.