"Rubral" tremor induced by a neuroleptic drug.
"Rubral" tremor is a rare movement disorder that occurs typically with midbrain damage. It is defined by its presence at rest, with sustained posture, and with movement. Whether it is a single-tremor disorder or a combination of two distinct tremors is debated. This report chronicles a severe neuroleptic induced "rubral" tremor in a patient who had had a stable posttraumatic ataxia. The dramatic response to benztropine and bromocriptine is illustrated in the videotape.
Friedman
J H
JH
Neuropsychiatry Research and Training Center, Institute for Mental Health, Cranston, Rhode Island.
D000328:Adult; D001590:Benztropine / Q000008:administration & dosage; D001971:Bromocriptine / Q000008:administration & dosage; D003342:Corpus Striatum / Q000187:drug effects / Q000503:physiopathology; D005476:Fluphenazine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D008297:Male; D009434:Neural Pathways / Q000187:drug effects / Q000503:physiopathology; D012012:Red Nucleus / Q000187:drug effects* / Q000503:physiopathology; D013378:Substantia Nigra / Q000187:drug effects / Q000503:physiopathology; D014202:Tremor / Q000139:chemically induced* / Q000503:physiopathology
D001590:Benztropine; D001971:Bromocriptine; C011825:fluphenazine depot; D005476:Fluphenazine