Successful surgical management of septic arthritis due to Trichosporon beigelii in a patient with acute myeloid leukaemia.
A Greek male with acute myeloid leukaemia (AML) developed a pyrexial illness while neutropenic and Trichosporon beigelii was isolated from his skin, blood and urine. This infection appeared to resolve with a rising neutrophil count, but recurred in the next episode of neutropenia. T. beigelii was isolated from an aspirate from an inflamed knee. Despite a rising neutrophil count resolution only occurred after surgical drainage and local irrigation with miconazole.
McWhinney
P H
PH
Division of Communicable Diseases, Royal Free Hospital School of Medicine, London, England.
Madgwick
J C
JC
Hoffbrand
A V
AV
Bhamra
A
A
Kibbler
C C
CC
D000293:Adolescent; D001170:Arthritis, Infectious / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D004322:Drainage; D016469:Fungemia / Q000382:microbiology; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008297:Male; D008825:Miconazole / Q000008:administration & dosage / Q000627:therapeutic use; D009181:Mycoses / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D012867:Skin / Q000382:microbiology; D007507:Therapeutic Irrigation; D014250:Trichosporon / Q000302:isolation & purification*; D014556:Urine / Q000382:microbiology
D008825:Miconazole