title: Ameloblastoma of the mandible with intracranial metastasis. A case study.
abstract: Ameloblastoma is an aggressive locally recurring neoplasm of odontogenic epithelium. We describe a case of a mandibular ameloblastoma with a 17-year history of local recurrences followed by two metachronous intracranial metastases. Central nervous system metastasis without pulmonary involvement is previously unreported in a living patient with ameloblastoma. The behavior of this tumor qualifies it as a malignant ameloblastoma.
authors.affiliation: Department of Otolaryngology, Johns Hopkins School of Medicine, Baltimore, Md.
authors.forename: S D
authors.initials: SD
authors.lastname: Phillips
authors.forename: R L
authors.initials: RL
authors.lastname: Corio
authors.forename: H
authors.initials: H
authors.lastname: Brem
authors.forename: D
authors.initials: D
authors.lastname: Mattox
mesh_terms: D000368:Aged; D000564:Ameloblastoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D004388:Dura Mater / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D009364:Neoplasm Recurrence, Local; D011859:Radiography