title: Hyperosmolar hyperglycemic nonketotic coma in Waldenström's macroglobulinemia associated with type II diabetes and complicated by pulmonary tuberculosis.
abstract: In this paper we describe a successfully treated case of hyperosmolar hyperglycemic non ketotic coma (HHNC). The HHNC was observed in a patient affected by Waldenström's macroglobulinemia, associated with type II diabetes and complicated by pulmonary tuberculosis. Hyperosmolar hyperglycemic nonketotic coma is a clinical condition with a high mortality rate associated with a severe increase in blood viscosity. This increase in blood viscosity justifies several clinical manifestations of the HHNC. We believe that an increase in the blood viscosity produced by the simultaneous presence of the single diseases mentioned above may have encouraged the development of hyperosmolar coma in the case reported.
authors.affiliation: Divisione medica Rizzi, Ospedale Niguarda Ca' Granda, Milano.
authors.forename: L
authors.initials: L
authors.lastname: Cirasino
authors.forename: G
authors.initials: G
authors.lastname: Thiella
authors.forename: R
authors.initials: R
authors.lastname: Invernizzi
authors.forename: A
authors.initials: A
authors.lastname: Silvani
authors.forename: S
authors.initials: S
authors.lastname: Ragaini
mesh_terms: D000368:Aged; D002908:Chronic Disease; D003131:Combined Modality Therapy; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000628:therapy; D006801:Humans; D006944:Hyperglycemic Hyperosmolar Nonketotic Coma / Q000150:complications / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D008297:Male; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000628:therapy; D008258:Waldenstrom Macroglobulinemia / Q000150:complications* / Q000628:therapy