[Effect of a new sweetening agent from Stevia rebaudiana on animals].
Animals received saccharol adequate (by sweetness) to sugar, and in 10- and 50-fold increased amounts. The data of chronic 10-month experiments studied in the time course after 2, 5, 10 months have permitted a conclusion that saccharol included into the ration during long periods, does not produce a significant effect on the parameters of metabolic processes and morphological picture of the internal organs in test animals. Saccharol in 50-fold increased amounts inhibits the activity of oxidative phosphorylation in the hepatic tissue of rats.
Smoliar
V I
VI
Karpilovskaia
E D
ED
Saliĭ
N S
NS
Tsapko
E V
EV
Lavrushenko
L F
LF
Gulich
M P
MP
Kryshevich
L P
LP
Grigorenko
S N
SN
D000821:Animal Feed; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D004305:Dose-Response Relationship, Drug; D008112:Liver Glycogen / Q000378:metabolism*; D008930:Mitochondria, Liver / Q000187:drug effects* / Q000378:metabolism; D008954:Models, Biological; D010085:Oxidative Phosphorylation / Q000187:drug effects; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology*; D010946:Plants, Medicinal; D051381:Rats; D012439:Saccharin / Q000008:administration & dosage / Q000494:pharmacology*; D013549:Sweetening Agents / Q000008:administration & dosage / Q000494:pharmacology*
D001786:Blood Glucose; D008112:Liver Glycogen; D010936:Plant Extracts; D013549:Sweetening Agents; D012439:Saccharin
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