title: [Ischemic hepatitis. Important differential diagnosis of increased levels of transaminases in the liver].
abstract: In patients with pathological findings in tests of liver function, ischemic hepatitis is an important differential diagnosis. This condition is most often seen in patients with coronary heart disease. Acute circulatory failure may induce reduced liver perfusion with extreme elevation in transaminase levels within three to five days. The values return to normal within five to ten days and in uncomplicated cases there is minimal cholestasis. Ischemic hepatitis may progress to fulminant hepatic failure. The diagnosis can be made by clinical examination and biochemical tests alone. Biopsy gives a characteristic picture of centrilobular liver cell necrosis which confirms the diagnosis, but is seldom necessary.
authors.affiliation: Medisinsk avdeling Harstad sykehus.
authors.forename: J D
authors.initials: JD
authors.lastname: Solli
authors.forename: K
authors.initials: K
authors.lastname: Nordgård
mesh_terms: D000368:Aged; D000410:Alanine Transaminase / Q000378:metabolism*; D001219:Aspartate Aminotransferases / Q000378:metabolism*; D003937:Diagnosis, Differential; D006505:Hepatitis / Q000175:diagnosis* / Q000201:enzymology; D006801:Humans; D007511:Ischemia / Q000175:diagnosis* / Q000201:enzymology; D008099:Liver / Q000201:enzymology*; D008102:Liver Circulation; D008297:Male
chemical_list: D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
vernacular_title: Iskemisk hepatitt. En viktig differensialdiagnose ved forhøyede levertransaminaseverdier.