title: [Effects of fenoverine on biliary kinetics evaluated by hepatobiliary scintigraphy with 99mTc-Br-IDA].
abstract: Hepatobiliary scintigraphy was used to evaluate the action of fenoverine in 16 patients suffering from dyskinesia of the biliary tract; the drug was administered in doses of 300 mg per day per os for 20 days, the patients being subjected to hepatobiliary scintigraphy before and after treatment. The following parameters--accurate indicators of the motor coordination of the biliary tract--were evaluated: tracer appearance time in the gallbladder (Tc) and in the intestine (Ti). After treatment there was a normalization of these two parameters which initially were extended. Statistical analysis showed a highly significant reduction in these times. Stress is laid on the importance of hepatobiliary scintigraphy in the diagnosis of biliary dyskinesia and on the effectiveness of fenoverine in the treatment of this conditions.
authors.affiliation: Istituto di Clinica Medica, Università di Palermo.
authors.forename: R
authors.initials: R
authors.lastname: Costa
authors.forename: M
authors.initials: M
authors.lastname: Cirrincione
authors.forename: G
authors.initials: G
authors.lastname: Cangialosi
authors.forename: M
authors.initials: M
authors.lastname: Chinnici
authors.forename: V
authors.initials: V
authors.lastname: Salerno
authors.forename: R
authors.initials: R
authors.lastname: Mannino
authors.forename: L
authors.initials: L
authors.lastname: Scaffidi
authors.forename: A
authors.initials: A
authors.lastname: Scaffidi
mesh_terms: D000284:Administration, Oral; D000328:Adult; D001657:Biliary Dyskinesia / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D001659:Biliary Tract / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007098:Imino Acids; D008099:Liver / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D010640:Phenothiazines / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors; D015899:Tomography, Emission-Computed, Single-Photon; D010879:Piperazines
chemical_list: D007098:Imino Acids; D015609:Organotechnetium Compounds; D010640:Phenothiazines; C046767:technetium Tc 99m iminodiacetic acid; C048314:fenoverine; D010879:Piperazines
vernacular_title: Effetti della fenoverina sulla cinetica biliare valutata con scintigrafia epatobiliare con 99mTc-Br-IDA.