Iodine supplementation in children receiving long-term parenteral nutrition.
In 18 children receiving long-term total parenteral nutrition (TPN) without iodide supplements, thyroid function test results were normal but serum iodide levels were greater than in control subjects (p less than 0.01). Iodine contamination of TPN solutions and fat emulsions accounted for only half of the recommended parenteral intake. Skin absorption of topical iodinated disinfectant may explain the adequate, if not excessive, iodine intake. We conclude that iodine is an unnecessary supplement in TPN solutions.
Moukarzel
A A
AA
Department of Pediatrics, Maimonides Medical Center, Brooklyn, New York.
Buchman
A L
AL
Salas
J S
JS
Vargas
J
J
Guss
W
W
Baron
H I
HI
Reyen
L
L
Ament
M E
ME
D000293:Adolescent; D000596:Amino Acids / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D004202:Disinfectants; D004573:Electrolytes; D005217:Fat Emulsions, Intravenous / Q000032:analysis; D005526:Food, Formulated / Q000032:analysis*; D005947:Glucose; D006801:Humans; D007223:Infant; D007455:Iodine / Q000008:administration & dosage / Q000032:analysis* / Q000097:blood; D008297:Male; D057947:Parenteral Nutrition Solutions; D010289:Parenteral Nutrition, Total; D011206:Povidone-Iodine; D012869:Skin Absorption; D012996:Solutions; D013960:Thyroid Function Tests
D000596:Amino Acids; D004202:Disinfectants; D004573:Electrolytes; D005217:Fat Emulsions, Intravenous; D057947:Parenteral Nutrition Solutions; D012996:Solutions; C545824:amino-acid, glucose, and electrolyte solution; D011206:Povidone-Iodine; D007455:Iodine; D005947:Glucose