A case of deletion of the short arm of chromosome 10 with severe hearing loss and brainstem dysfunction.
A male newborn infant with a deletion of the short arm of chromosome 10p 14 was described. In addition to the typical clinical features, electrophysiologic studies showed brainstem dysfunction and severe hearing loss when examined with auditory brainstem response and photopalpebral reflex. These electrophysiologic studies may be of benefit for early evaluation of brainstem functions and hearing ability of the patients of such chromosomal aberration and may also be useful predictors of psychomotor development.
Kinoshita
Y
Y
Department of Pediatrics, Kansai Medical University, Osaka, Japan.
Tanaka
Y
Y
Yasuhara
A
A
Matsuzaki
S
S
Kuriki
H
H
Kobayashi
Y
Y
D000015:Abnormalities, Multiple / Q000235:genetics*; D001300:Audiometry, Evoked Response; D001933:Brain Stem / Q000503:physiopathology*; D002872:Chromosome Deletion; D002879:Chromosomes, Human, Pair 10; D003638:Deafness / Q000175:diagnosis / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D008297:Male