title: Acute and long-term outcome of narrowed saphenous venous grafts treated by endoluminal stenting and directional atherectomy.
abstract: Angioplasty of the narrowed saphenous vein bypass grafts remains a difficult challenge. Over a 37-month period at this institution, 119 of 176 interventions (68%) on saphenous vein grafts (average age 8.3 years from bypass surgery to graft intervention) were performed using either directional coronary atherectomy (n = 35) or Palmaz-Schatz intracoronary stents (n = 84), representing 37% of all stents and 15% of all atherectomies during the study period, respectively. Of the 57 saphenous vein graft lesions treated with conventional balloon angioplasty during this period, 49 (86%) had 1 or more contraindications to stenting or directional atherectomy (thrombus, total occlusion, reference vessel less than 3 mm in diameter). The acute success rate was 99% for stents (1 failure to dilate) and 94% for directional atherectomy (2 failures to cross the lesion with the atherectomy device). Lumen diameter increased from 0.9 to 3.6 mm (reference vessel 3.6) for stents, and from 0.9 to 3.5 mm (reference 3.8) for atherectomy (for all comparisons, p = not significant), with no major complications (abrupt or subabrupt closure, emergent coronary bypass surgery, death, or Q-wave myocardial infarctions). During the same time period 50 of 57 vein grafts (88%) rejected for stenting or atherectomy were dilated successfully by conventional balloon angioplasty, with 3 patients (5%) requiring emergent coronary bypass surgery. Angiographic follow-up was available for 50 of 64 eligible patients (78%).(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Charles A. Dana Research Institute, Boston, Massachusetts.
authors.forename: R M
authors.initials: RM
authors.lastname: Pomerantz
authors.forename: R E
authors.initials: RE
authors.lastname: Kuntz
authors.forename: J P
authors.initials: JP
authors.lastname: Carrozza
authors.forename: R F
authors.initials: RF
authors.lastname: Fishman
authors.forename: M
authors.initials: M
authors.lastname: Mansour
authors.forename: S J
authors.initials: SJ
authors.lastname: Schnitt
authors.forename: R D
authors.initials: RD
authors.lastname: Safian
authors.forename: D S
authors.initials: DS
authors.lastname: Baim
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D001161:Arteriosclerosis / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000628:therapy*; D001026:Coronary Artery Bypass; D005260:Female; D005500:Follow-Up Studies; D006083:Graft Occlusion, Vascular / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015641:Radiography, Interventional; D012501:Saphenous Vein / Q000000981:diagnostic imaging / Q000637:transplantation*; D015607:Stents