Accumulation of hypotaurine in tissues and urine of rats fed an excess methionine diet.
Hypotaurine increased in some tissues, especially in muscle, and urine of rats fed methionine excess diet. The significant depression of the body weight and food intake of rats caused by excess methionine was remarkably alleviated as previous reports and hypotaurine content in muscle and urine increased further by supplement with glycine to the excess methionine diet.
Kasai
T
T
Department of Agricultural Chemistry, Faculty of Agriculture, Hokkaido University, Sapporo, Japan.
Ogo
Y
Y
Otobe
Y
Y
Kiriyama
S
S
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D007668:Kidney / Q000378:metabolism; D008297:Male; D008715:Methionine / Q000009:adverse effects*; D009132:Muscles / Q000378:metabolism; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000378:metabolism; D013654:Taurine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000652:urine
D013654:Taurine; C003949:hypotaurine; D008715:Methionine