Dialysis in patients with upper urinary tract transitional cell carcinoma.
In some patients with primary malignant disease of the kidney the only way of achieving a cure may involve radical surgery. If the tumour is bilateral or involves a solitary kidney, renal failure may be unavoidable. The role of dialysis and transplantation in these patients following "curative" cancer surgery is not clear. A review of the literature and experience with 4 patients who ultimately had bilateral nephrectomies for multiple recurrent upper tract urothelial malignancy is reported. These 4 patients remained free of tumour recurrence on dialysis at 5, 8, 12 and 72 months respectively since commencing dialysis, although 2 have died from unrelated causes. It would seem reasonable to offer dialysis followed by subsequent transplantation in this group of patients after a period of 1 to 2 years has elapsed without any evidence of malignant recurrence.
Persad
R A
RA
Department of Urology, Royal Infirmary Hospital, Bristol.
Gillatt
D A
DA
Harrison
P
P
Abrams
P H
PH
D000328:Adult; D002295:Carcinoma, Transitional Cell / Q000601:surgery*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000628:therapy*; D007680:Kidney Neoplasms / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009392:Nephrectomy / Q000009:adverse effects*; D011183:Postoperative Complications / Q000628:therapy*; D006435:Renal Dialysis; D014513:Ureter / Q000601:surgery; D014516:Ureteral Neoplasms / Q000601:surgery*