[Bone marrow graft in hereditary diseases].
Since 1968, bone marrow transplantation became the first line therapy for selected metabolic and immunological hereditary disorders. Actually, advances in the supportive care in bone marrow transplantation and a better knowledge of the immunology of BMT complications has been associated with a better disease correction and an increase in long term survival. New approaches are under investigation and include: hematopoietic growth factors, enzymatic replacement and gene therapy. However at the present time BMT is still the only curative treatment for selected hereditary disorders.
Bujan
W
W
Unité d'Hémato-Oncologie, Hôpital Universitaire des Enfants, Bruxelles.
Ferster
A
A
Devalck
C
C
Vamos
E
E
Mascart
F
F
Denis
R
R
Azzi
N
N
Vergauwen
P
P
Sariban
E
E
D016026:Bone Marrow Transplantation; D002609:Chediak-Higashi Syndrome / Q000628:therapy; D030342:Genetic Diseases, Inborn / Q000145:classification / Q000628:therapy*; D006133:Growth Substances / Q000627:therapeutic use; D006801:Humans; D008661:Metabolism, Inborn Errors / Q000628:therapy; D014923:Wiskott-Aldrich Syndrome / Q000628:therapy
D006133:Growth Substances
La greffe de moelle dans les maladies héréditaires.