Trisomy 18 and a constitutional maternal translocation (2;18).
Parental chromosomes are usually not analyzed in cases of trisomy 18 because the extra 18 is assumed to have arisen through a meiotic nondisjunctional event. We report on a case of a trisomy 18 and a maternal translocation (2;18)(q34;q12).
Teshima
I E
IE
Department of Genetics, Hospital for Sick Children, Toronto, Canada.
Winsor
E J
EJ
Van Allen
M I
MI
D000022:Abortion, Spontaneous; D000328:Adult; D002478:Cells, Cultured; D002871:Chromosome Banding; D002887:Chromosomes, Human, Pair 18; D002889:Chromosomes, Human, Pair 2; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D008214:Lymphocytes / Q000473:pathology; D008831:Microcephaly / Q000235:genetics*; D011247:Pregnancy; D014178:Translocation, Genetic; D014314:Trisomy