title: In vitro antimicrobial effects of fresh split skin, homologous-cultured epithelium and porcine split skin grafts for wound coverage.
abstract: Various biological dressings, for example, human fresh and cadaver skin grafts, homologous cultured human epithelium and deep frozen porcine split skin (Lyocutis), have been used to treat skin loss. Each of these biological dressings has its advantages and disadvantages. The antimicrobial properties of each dressing type are important since bactericidal activity influences the lifespan of the transplanted tissue. In the present study the in vitro antimicrobial effects of human fresh skin, homologous cultured epithelium and Lyocutis were compared to in vivo bactericidal activity of these dressings and possible clinical applications are recommended.
authors.affiliation: Department of Plastic and Reconstructive Surgery, National Institute for Cancer Research, Genova, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Franchelli
authors.forename: M
authors.initials: M
authors.lastname: Muggianu
authors.forename: R
authors.initials: R
authors.lastname: Dalla Costa
authors.forename: M L
authors.initials: ML
authors.lastname: Rainero
authors.forename: E
authors.initials: E
authors.lastname: Campora
authors.forename: P L
authors.initials: PL
authors.lastname: Santi
mesh_terms: D001684:Biological Dressings; D001706:Biopsy; D002056:Burns / Q000601:surgery*; D002448:Cell Adhesion; D002478:Cells, Cultured; D004847:Epithelial Cells; D004848:Epithelium / Q000382:microbiology; D006801:Humans; D012867:Skin / Q000166:cytology / Q000382:microbiology*; D016038:Skin Transplantation / Q000379:methods*; D014945:Wound Healing