title: Mutations on the second chromosome affecting the Drosophila eye.
abstract: In the developing eye of Drosophila, cell interactions appear to be responsible for organising undifferentiated cells into unit eyes, or ommatidia. Extensive mutagenesis has been used to search for mutations affecting the development and differentiation of ommatidia. These mutations have been characterized using sections of adults and immunocytochemistry of imaginal discs. Fourteen loci on the second chromosome are described that affect the spacing of the preclusters, the differentiation of ommatidial cells, orientation of the ommatidia, or architecture of the adult retina, that cause retinal degeneration in larval or pupal eye discs, or that cause homeotic transformation of part of the head.
authors.affiliation: Howard Hughes Medical Institute, University of California, Berkeley 94720.
authors.forename: N E
authors.initials: NE
authors.lastname: Baker
authors.forename: K
authors.initials: K
authors.lastname: Moses
authors.forename: D
authors.initials: D
authors.lastname: Nakahara
authors.forename: M C
authors.initials: MC
authors.lastname: Ellis
authors.forename: R W
authors.initials: RW
authors.lastname: Carthew
authors.forename: G M
authors.initials: GM
authors.lastname: Rubin
mesh_terms: D000818:Animals; D002875:Chromosomes; D003315:Cornea / Q000502:physiology; D004330:Drosophila / Q000235:genetics; D005123:Eye / Q000166:cytology; D006720:Homozygote; D009154:Mutation / Q000235:genetics; D009799:Ocular Physiological Phenomena; D010641:Phenotype