title: Optimization of three-dimensional T1-weighted gradient-echo imaging of the cervical spine.
abstract: Various parameters of the three-dimensional (3D) T1-weighted magnetization-prepared rapid acquisition gradient-echo (MP-RAGE) sequence were evaluated to improve spatial resolution while maintaining T1 contrast and a short examination time in imaging of the cervical spine in volunteers. The most dramatic improvements in image resolution occurred by decreasing section thickness to 1.2 mm and increasing the in-plane matrix to 192 x 256, with a 230-mm field of view. The increase in imaging time due to the increased matrix was offset by the elimination of the preparation pulse and wait time, without dramatic changes in contrast-to-noise ratio or overall image quality. Optimum parameters included elimination of the preparation pulse and wait time, 12 degrees flip angle, 192 x 256 matrix, 1.2-mm section thickness, nonselective excitation (coronal acquisition), RF spoiling, and standard k-space ordering, for an examination time of 5 minutes 21 seconds.
authors.affiliation: Division of Radiology, Cleveland Clinic Foundation, OH 44195-5129.
authors.forename: J S
authors.initials: JS
authors.lastname: Ross
authors.forename: J A
authors.initials: JA
authors.lastname: Tkach
authors.forename: J
authors.initials: J
authors.lastname: Dillinger
authors.forename: P M
authors.initials: PM
authors.lastname: Ruggieri
authors.forename: T J
authors.initials: TJ
authors.lastname: Masaryk
authors.forename: M T
authors.initials: MT
authors.lastname: Modic
mesh_terms: D002574:Cervical Vertebrae / Q000033:anatomy & histology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*