On the influence of the sugar moiety on the antigonadotropic activity of luteoline glycosides.
Luteolin-7-glucoside and luteolin-7-glucuronide were isolated from Lycopus europaeus L. (Lamiaceae) and identified by 1H- and 13C-NMR spectroscopy. Luteolin-7-glucuronide proved to be active against PMSG in vitro as well as in vivo, whereas the other flavone glycosides occurring in the plant were completely inactive.
Gumbinger
H G
HG
Centre C.N.R.S.I.N.S.E.R.M. de Pharmakologie Endocrinologie, Montpellier, France.
Winterhoff
H
H
Wylde
R
R
Sosa
A
A
D000818:Animals; D002241:Carbohydrates / Q000737:chemistry / Q000494:pharmacology*; D005260:Female; D005419:Flavonoids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D005960:Glucosides / Q000737:chemistry / Q000494:pharmacology*; D006064:Gonadotropins, Equine / Q000037:antagonists & inhibitors*; D047311:Luteolin; D051381:Rats; D011919:Rats, Inbred Strains
D002241:Carbohydrates; D005419:Flavonoids; D005960:Glucosides; D006064:Gonadotropins, Equine; C075406:luteolin-7-glucuronide; C066408:luteolin-7-glucoside; D047311:Luteolin