Sister chromatid exchange frequency in breast cancer cases.
Sister chromatid exchange (SCE) were studied in 22 patients with breast cancer (i.e., four stage II; 12 stage III, six stage IV) and 10 normal healthy females as age-matched controls. The data obtained in these cases followed a Poisson distribution. An apparent increase in the average rate of SCE/cell was observed with the advancing stage of breast cancer.
Husain
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SA
Department of Human Biology and Human Genetics, Guru Nanak Dev University, Amritsar, Punjab, India.
Balasubramanian
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Bamezai
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R
D001943:Breast Neoplasms / Q000235:genetics* / Q000473:pathology; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D016012:Poisson Distribution; D012854:Sister Chromatid Exchange / Q000235:genetics*