C wave of electroretinogram and visual evoked response in optic neuritis due to demyelinating diseases.
In 21 consecutive cases with unilateral optic neuritis due to demyelinating disease, ERG, C wave of ERG and VER were recorded and studied in both eyes. Also 8 cases suffering from optic atrophy due to trauma or glaucoma were included. The analysis of data shows that the C-wave is significantly diminished in both eyes, namely the affected and the sound, in the cases of optic neuritis. Also in comparison to VER, C wave has a comparative probability in diagnosing optic neuritis due to demyelinating disease. The C wave of ERG is normal in the cases of optic atrophy. The mechanism of C wave involvement during the course of demyelinating disease may be related with an abnormality of the ionic homeostasis of the subretinal space.
Moschos
M
M
Laboratory of Electrophysiology, Athens University Eye Clinic, Greece.
Brouzas
D
D
D000293:Adolescent; D000328:Adult; D000368:Aged; D003711:Demyelinating Diseases / Q000150:complications / Q000503:physiopathology*; D004596:Electroretinography; D005074:Evoked Potentials, Visual; D005131:Eye Injuries / Q000503:physiopathology; D005901:Glaucoma / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D009896:Optic Atrophy / Q000503:physiopathology; D009902:Optic Neuritis / Q000209:etiology / Q000503:physiopathology*; D014792:Visual Acuity