title: [Nephropathy in human immunodeficiency virus infection].
abstract: BACKGROUND
  Patients with the human immunodeficiency virus (HIV) infection may present different types of nephropathy with focal segmentary glomerulosclerosis (FSGS) being the most specific lesion associated to HIV (HIVN). The prevalence of this entity varies between 1 to 23%. These differences have been attributed to ethnic factors and/or intravenous drug addiction (IVDA). The renal alterations presented in these patients with HIV infection were analyzed.
  
  
  METHODS
  Two groups of patients were studied: Group I with 300 consecutive patients with advanced HIV infection (complex related with AIDS) treated with zidovudine without initial kidney infection followed for a mean of 19 +/- 11 months (99% caucasian, 65% IVDA, 66% AIDS); and group II with 11 patients with HIV infection remitted for kidney involvement (4 on hemodialysis).
  
  
  RESULTS
  Group I: 26 cases (9%) presented acute reversible kidney failure (12 prerenal, 9 nephrotoxicity and 5 mixed). No patient presented HIVN criteria. Group II: one black patient developed HIVN and had no known risk factors. The remaining patients presented glomerular changes different from those of HIVN.
  
  
  CONCLUSIONS
  The scarce prevalence of human immunodeficiency virus nephropathy in the present series is of note despite the high number of intravenous drug addicts included suggesting that ethnic factors determine the differences observed in different series. The most frequent kidney disturbances seen are those related with infectious complications associated to the acquired immunodeficiency syndrome and the treatment of the same.
authors.affiliation: Servicio de Nefrología, Hospital Clínic i Provincial, Universidad de Barcelona.
authors.forename: N
authors.initials: N
authors.lastname: Esforzado
authors.forename: T
authors.initials: T
authors.lastname: Feliz
authors.forename: J
authors.initials: J
authors.lastname: Almirall
authors.forename: A
authors.initials: A
authors.lastname: Torras
authors.forename: J M
authors.initials: JM
authors.lastname: Miró
authors.forename: J M
authors.initials: JM
authors.lastname: Gatell
authors.forename: L
authors.initials: L
authors.lastname: Revert
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D058186:Acute Kidney Injury / Q000150:complications / Q000453:epidemiology; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000150:complications* / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011507:Proteinuria / Q000150:complications / Q000453:epidemiology; D012189:Retrospective Studies
vernacular_title: Nefropatía en la infección por el virus de la inmunodeficiencia humana.