title: Medical management of spinal epidural abscesses: case report and review.
abstract: Although the traditional management of spinal epidural abscesses includes antibiotic therapy and surgical drainage, numerous reports have appeared in the literature that describe a nonsurgical approach. We report the successful nonsurgical management of a case of an extensive spinal epidural abscess in which the patient was closely monitored by serial studies with magnetic resonance imaging. Review of the literature from 1970 to 1990 revealed 37 cases that describe conservative management of spinal epidural abscesses. Despite successful conservative management reported for some cases, sudden neurological deterioration of patients receiving appropriate antibiotic therapy has also occurred. A true index of the success of nonsurgical therapy is difficult to discern since cases may have been selectively reported and unsuccessful attempts at conservative management may have never been reported once a laminectomy was performed. A prospective investigation that includes clearly defined indications for conservative management vs. surgical intervention and that can be studied with an intention-to-treat analysis is needed.
authors.affiliation: Department of Medicine, University of Maryland Medical Center, Baltimore.
authors.forename: D
authors.initials: D
authors.lastname: Wheeler
authors.forename: P
authors.initials: P
authors.lastname: Keiser
authors.forename: D
authors.initials: D
authors.lastname: Rigamonti
authors.forename: S
authors.initials: S
authors.lastname: Keay
mesh_terms: D000038:Abscess / Q000175:diagnosis / Q000628:therapy*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004322:Drainage; D004824:Epidural Space; D006801:Humans; D008297:Male; D008875:Middle Aged; D013118:Spinal Cord Diseases / Q000175:diagnosis / Q000628:therapy; D013290:Streptococcal Infections / Q000175:diagnosis / Q000628:therapy*
chemical_list: D000900:Anti-Bacterial Agents