New observations on the distribution of an old and forgotten model of enteritis in rats.
Human serum injected intravenously into rats caused multiple foci of acute enteritis. The enteritis had a predilection for the antimesenteric side of the intestine and for the zones between circumferential vessels. Despite their antimesenteric location, Peyer's patches tended to be spared. The details of distribution suggest that a gradient related to intestinal blood flow plays a role in development of the enteritis.
Levine
S
S
Pathology Department, New York Medical College, Valhalla 10595.
Saltzman
A
A
D000818:Animals; D001798:Blood Proteins / Q000009:adverse effects; D004195:Disease Models, Animal; D004751:Enteritis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D007275:Injections, Intravenous; D007422:Intestines / Q000098:blood supply; D008297:Male; D010581:Peyer's Patches / Q000473:pathology; D051381:Rats; D011917:Rats, Inbred Lew; D011919:Rats, Inbred Strains; D012039:Regional Blood Flow / Q000502:physiology; D013997:Time Factors
D001798:Blood Proteins