Use of ciprofloxacin in an infant with ventriculitis.
Ciprofloxacin was used successfully in a neonate with ventriculitis caused by a multiply resistant strain of Enterobacter cloacae. Limited pharmacokinetic data indicated that adequate concentrations of drug could be attained in cerebrospinal fluid.
Goepp
J G
JG
Department of Pediatrics, Johns Hopkins Hospital, Baltimore, Maryland 21205.
Lee
C K
CK
Anderson
T
T
Dick
J D
JD
Stokoe
J M
JM
Eiden
J
J
D002552:Cerebral Ventricles; D002939:Ciprofloxacin / Q000032:analysis / Q000493:pharmacokinetics / Q000627:therapeutic use*; D004352:Drug Resistance, Microbial; D004660:Encephalitis / Q000097:blood / Q000134:cerebrospinal fluid / Q000188:drug therapy* / Q000382:microbiology; D016972:Enterobacter cloacae / Q000187:drug effects; D004756:Enterobacteriaceae Infections / Q000097:blood / Q000134:cerebrospinal fluid / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007223:Infant
D002939:Ciprofloxacin