title: Neurological complications after thrombolytic treatment for acute myocardial infarction: emphasis on unprecedented manifestations.
abstract: We examined 348 patients who underwent thrombolytic treatment for acute myocardial infarction. Nine patients (2.58%) developed neurological complications related directly or indirectly to this procedure. Cerebral hemorrhage occurred in 3 patients; 2 patients had transient ischemic attacks, 1 had syncope, another had psychomotor agitation and 2 patients presented seizures during the infusion of the thrombolytic agent, without hemodynamic abnormalities. This latter feature had never been described before.
authors.affiliation: Department of Neurology, University of São Paulo, Brazil.
authors.forename: P
authors.initials: P
authors.lastname: Caramelli
authors.forename: E G
authors.initials: EG
authors.lastname: Mutarelli
authors.forename: B
authors.initials: B
authors.lastname: Caramelli
authors.forename: B
authors.initials: B
authors.lastname: Tranchesi
authors.forename: F
authors.initials: F
authors.lastname: Pileggi
authors.forename: M
authors.initials: M
authors.lastname: Scaff
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D002561:Cerebrovascular Disorders / Q000188:drug therapy / Q000209:etiology; D004789:Enzyme Activation; D005260:Female; D005343:Fibrinolytic Agents; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D010672:Phenytoin / Q000627:therapeutic use; D012640:Seizures / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage
chemical_list: D005343:Fibrinolytic Agents; D010672:Phenytoin; D006493:Heparin; D010959:Tissue Plasminogen Activator