Isolation and identification of xochitloldione and isoxochitlolone from Cnidosculus urens.
Major components of MeOH extracts from the plant roots of Cnidosculus urens purified by cc and tlc and crystallization were lupeol acetate and the previously unreported compounds isoxochitlolone [1] and xochitloldione [2], which were identified through mass, ir, nmr, and uv spectroscopy and X-ray crystallography. In preliminary testing, isoxochitlolone has been found to be active against Escherichia coli and Staphylococcus aureus.
Dominguez
X A
XA
Departamento de Quimica, Instituto Tecnologico y de Estudios Superiores de Monterrey, Mexico.
Sanchez
H
H
Garcia
S
S
Espinosa
G
G
Williams
H J
HJ
Ortiz
C
C
Scott
A I
AI
Reibenspies
J H
JH
D000900:Anti-Bacterial Agents / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology; D002855:Chromatography, Thin Layer; D003460:Crystallization; D003512:Cyclohexanones / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D008800:Mexico; D008826:Microbial Sensitivity Tests; D010636:Phenols / Q000032:analysis / Q000302:isolation & purification* / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects; D014961:X-Ray Diffraction
D000900:Anti-Bacterial Agents; D003512:Cyclohexanones; D010636:Phenols; C075492:isoxochitlolone; C075493:xochitloldione