title: Deltamethrin residues in milk and tissues of lactating dairy cows.
abstract: Lactating dairy cows were fed deltamethrin (2 or 10 mg kg-1 feed) for 28 consecutive days and deltamethrin residues measured in milk and tissues. Deltamethrin residues were higher relative to dose administered. The order of relative concentrations of deltamethrin in tissues, measured 1, 4, and 9 days after the last dose was: renal fat greater than subcutaneous fat greater than forequarter muscle greater than hindquarter muscle greater than liver greater than kidney. Depletion of deltamethrin residues in milk was very rapid indicating the half-life of the insectide of about 1 day. Trace amounts of deltamethrin metabolites 3-(2,2-dibromovinyl)-2,2-dimethylcyclopropane carboxylic acid (less than 0.0235 ppm) and 3-phenoxybenzoic acid (less than 0.034 ppm) were also detected in milk and tissues of treated cows.
authors.affiliation: Centre for Food and Animal Research, Research Branch, Agriculture Canada, Ottawa, Ontario.
authors.forename: M H
authors.initials: MH
authors.lastname: Akhtar
authors.forename: C
authors.initials: C
authors.lastname: Danis
authors.forename: H L
authors.initials: HL
authors.lastname: Trenholm
authors.forename: K E
authors.initials: KE
authors.lastname: Hartin
mesh_terms: D000273:Adipose Tissue / Q000737:chemistry / Q000378:metabolism; D000284:Administration, Oral; D000821:Animal Feed; D000818:Animals; D002417:Cattle / Q000378:metabolism*; D002849:Chromatography, Gas; D004305:Dose-Response Relationship, Drug; D002523:Edible Grain; D005260:Female; D005506:Food Contamination; D008401:Gas Chromatography-Mass Spectrometry; D006207:Half-Life; D007306:Insecticides / Q000008:administration & dosage / Q000032:analysis / Q000493:pharmacokinetics*; D007668:Kidney / Q000737:chemistry / Q000378:metabolism; D007774:Lactation / Q000378:metabolism*; D008099:Liver / Q000737:chemistry / Q000378:metabolism; D008892:Milk / Q000032:analysis / Q000378:metabolism; D009132:Muscles / Q000737:chemistry / Q000378:metabolism; D009570:Nitriles; D010573:Pesticide Residues / Q000032:analysis / Q000493:pharmacokinetics*; D011722:Pyrethrins / Q000008:administration & dosage / Q000032:analysis / Q000493:pharmacokinetics*
chemical_list: D007306:Insecticides; D009570:Nitriles; D010573:Pesticide Residues; D011722:Pyrethrins; C017180:decamethrin