title: Malignant rhabdoid tumor of the central nervous system with subarachnoid dissemination.
abstract: A case of primary central nervous system malignant rhabdoid tumor is presented. Clinical, radiological, and histopathological findings are described in detail. Because of a relatively long clinical course after presentation, it was possible to assess the clinical and radiological response to different treatment modalities: surgery, chemotherapy, and radiotherapy. Despite the complete clinical and radiological response that was achieved after subtotal excision, two cycles of chemotherapy, and high-dose radiotherapy, the tumor recurred within 4 months of completion of the treatment, with wide subarachnoid dissemination. Radiotherapy treatment of whole cranial axis is recommended.
authors.affiliation: Department of Radiation Oncology, Saskatoon Cancer Centre, Saskatchewan, Canada.
authors.forename: A L
authors.initials: AL
authors.lastname: Agranovich
authors.forename: L C
authors.initials: LC
authors.lastname: Ang
authors.forename: R W
authors.initials: RW
authors.lastname: Griebel
authors.forename: N L
authors.initials: NL
authors.lastname: Kobrinsky
authors.forename: N
authors.initials: N
authors.lastname: Lowry
authors.forename: S P
authors.initials: SP
authors.lastname: Tchang
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D002675:Child, Preschool; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local; D013346:Subarachnoid Space / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed