[Oxygenated free radicals and vascular pathology].
Oxygen free radicals are used as a weapon by neutrophil morphopolynuclear cells, monocytes and macrophages against bacterial attacks. They do interact with arachidonic acid cascade catabolism that means they stimulate too, platelet cells and endothelial cells activity (EDRF is indeed "NO"). They prime all along inflammatory process and thrombosis which are main items of the pathology of vessels.
Emerit
J
J
Groupe Hospitalier Pitié-Salpêtrière, Paris.
Marchand
A
A
D005609:Free Radicals / Q000378:metabolism*; D006487:Hemostasis / Q000502:physiology; D006801:Humans; D007249:Inflammation / Q000209:etiology / Q000503:physiopathology; D010084:Oxidation-Reduction; D013927:Thrombosis / Q000209:etiology / Q000503:physiopathology; D014652:Vascular Diseases / Q000097:blood / Q000209:etiology* / Q000503:physiopathology
D005609:Free Radicals
Radicaux libres oxygénés et pathologie vasculaire.