Cellular responses of laboratory mice to feedings of Ornithodoros talaje (Acari: Argasidae) larvae.
Studies were carried out in which laboratory mice were subjected to sequential feedings by slow feeding Ornithodoros talaje (Guerín-Méneville) larvae to detect and characterize the host cellular response. After the first exposure, histological evidence showed a strong neutrophil infiltration at the site of attachment and feeding. By the third exposure, a marked shift to lymphocytes was noted in the mouse tissues using histological preparations of the feeding ticks. Lymphocyte proliferation tests also provided indirect evidence of a host lymphocyte response as a result of the three tick exposures and feedings.
Need
J T
JT
Department of Entomology and Nematology, University of Florida, Gainesville 32611.
Butler
J F
JF
Peck
A B
AB
D000818:Animals; D004817:Epidermis / Q000469:parasitology* / Q000473:pathology; D005260:Female; D007111:Immunity, Cellular; D007249:Inflammation; D007814:Larva / Q000276:immunology; D008213:Lymphocyte Activation; D051379:Mice; D013984:Tick Infestations / Q000276:immunology* / Q000473:pathology; D013987:Ticks / Q000276:immunology*