title: Streptokinase treatment of a thrombosed Björk-Shiley prosthesis in the aortic position.
abstract: Dysfunction of a mechanical prosthetic valve caused by thrombus formation is usually treated surgically. A patient with a thrombosed Björk-Shiley valve in the aortic position was treated successfully with intravenous streptokinase. The considerable improvement in the patient's clinical condition and the phonocardiographic, echocardiographic, and cinefluoroscopic evidence of normalisation of prosthetic valve function established the efficacy of thrombolytic therapy of a thrombosed prosthetic valve in this patient.
authors.affiliation: Department of Cardiology, KEM Hospital, Parel, Bombay, India.
authors.forename: V K
authors.initials: VK
authors.lastname: Mehan
authors.forename: B V
authors.initials: BV
authors.lastname: Dalvi
authors.forename: P A
authors.initials: PA
authors.lastname: Kale
mesh_terms: D000328:Adult; D001021:Aortic Valve; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010701:Phonocardiography; D013300:Streptokinase / Q000627:therapeutic use*; D013927:Thrombosis / Q000188:drug therapy* / Q000209:etiology
chemical_list: D013300:Streptokinase