title: Acquired airway hyperresponsiveness from nonimmunogenic irritant exposure.
abstract: The question of whether nonallergic airway hyperresponsiveness is an acquired or an inherent phenomenon is important in the understanding of occupational lung disease, as it has implications for the management and prevention of occupational disease. This chapter reviews the evidence suggesting that airway hyperresponsiveness may be acquired as a result of exposure to irritants in the workplace.
authors.affiliation: Department of Medicine, University of British Columbia, Vancouver, Canada.
authors.forename: S M
authors.initials: SM
authors.lastname: Kennedy
mesh_terms: D000403:Airway Resistance / Q000187:drug effects; D006801:Humans; D007509:Irritants / Q000009:adverse effects*; D008171:Lung Diseases / Q000139:chemically induced* / Q000453:epidemiology / Q000503:physiopathology; D009784:Occupational Diseases / Q000139:chemically induced* / Q000453:epidemiology / Q000503:physiopathology; D016273:Occupational Exposure
chemical_list: D007509:Irritants