title: Prescribing therapy for depression: the role of learned resourcefulness, a failure to replicate.
abstract: Work in 1985 by Simons, Lustman, Wetzel, and Murphy showed that a patient's score on Rosenbaum's self-control scale predicted differential response to treatments for depression, with a high score predicting a good outcome with talking therapy and a low score a good outcome with drug therapy. This study of 37 patients did not replicate those findings. Using the same paradigm, we predicted response correctly 7 times and incorrectly 16 times, a clear failure. A valid method for choosing the best treatment for a patient with major depression remains to be found.
authors.affiliation: Department of Psychiatry, Washington University School of Medicine, Louis, Missouri 63110.
authors.forename: R D
authors.initials: RD
authors.lastname: Wetzel
authors.forename: G E
authors.initials: GE
authors.lastname: Murphy
authors.forename: R M
authors.initials: RM
authors.lastname: Carney
authors.forename: P
authors.initials: P
authors.lastname: Whitworth
authors.forename: M A
authors.initials: MA
authors.lastname: Knesevich
mesh_terms: D000328:Adult; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003131:Combined Modality Therapy; D003866:Depressive Disorder / Q000523:psychology / Q000628:therapy*; D005260:Female; D006801:Humans; D007389:Internal-External Control; D008297:Male; D008875:Middle Aged; D010555:Personality Inventory
chemical_list: D000929:Antidepressive Agents, Tricyclic