title: Electrochemically modulated optrode for glucose.
abstract: One of the problems with fibre-optic sensors is the difficulty of finding reversible indicator reagents. This is a particular problem for fibre-optic glucose sensors. The development of an electrochemically modulated fibre-optic probe or optrode has been proposed as a convenient solution. Here the indicator reagent is regenerated electrochemically. In this work a design is proposed that offers considerable advantages in practical applications. In particular, it can be used in the same way as conventional optrodes. The optimization of working parameters and the application of the optrode to flow analysis under steady-state and flow-injection conditions is described.
authors.affiliation: Department of Chemistry, National University of Singapore, Kent Ridge.
authors.forename: H
authors.initials: H
authors.lastname: Gunasingham
authors.forename: C H
authors.initials: CH
authors.lastname: Tan
mesh_terms: D015374:Biosensing Techniques; D004563:Electrochemistry; D004795:Enzyme Stability; D005336:Fiber Optic Technology; D005947:Glucose / Q000032:analysis*; D006571:Heterocyclic Compounds / Q000737:chemistry; D007202:Indicators and Reagents; D013053:Spectrophotometry
chemical_list: D006571:Heterocyclic Compounds; D007202:Indicators and Reagents; C063887:tetrathiafulvalene; D005947:Glucose