Structural consensus of RNA templates replicated by Q beta replicase.
Q beta replicase replicates a variety of enzyme-specific small RNAs in addition to the phage genomic RNA. The sequence analysis has revealed that all these RNAs are potentially capable of forming a consensus secondary structure element. It represents a stalk which is formed by the 5'-GGG ... and ... CCCA-3' complementary stretches at the termini of the replicating RNA molecules and adjacent 5'- and 3'-hairpins, which may form a stacking with the stalk. The structure found is rather similar to the analogous structure in the tRNA molecule. The genomic RNA of the Q beta phage and other related phages can also form a similar structural element.
Voronin
L A
LA
Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region.
D001483:Base Sequence; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D011777:Q beta Replicase / Q000378:metabolism*; D012333:RNA, Messenger / Q000096:biosynthesis / Q000737:chemistry*; D012343:RNA, Transfer / Q000737:chemistry; D013698:Templates, Genetic
D012333:RNA, Messenger; D012343:RNA, Transfer; D011777:Q beta Replicase