title: Patchy distribution of rejection changes in small intestinal transplantation.
abstract: The aim of this study is to determine the distribution of histological changes of rejection in small intestinal transplantation. Thirty-nine rats were randomized into two groups: group I (n = 15), syngeneic transplants and group II (n = 24), allogeneic transplants. Grafts were excised and examined on days 2, 4, and 8 after transplantation. All grafts of the syngeneic group showed normal mucosa by day 4. However, by this time, all grafts of the allogeneic group demonstrated rejection changes with a patchy distribution in the mucosa. Therefore, with a biopsy from the stoma site there is a risk of missing early rejection.
authors.affiliation: Department of Pediatric Surgery, Juntendo University School of Medicine, Tokyo, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Yamataka
authors.forename: T
authors.initials: T
authors.lastname: Miyano
authors.forename: K
authors.initials: K
authors.lastname: Fukunaga
authors.forename: H
authors.initials: H
authors.lastname: Kobayashi
authors.forename: M
authors.initials: M
authors.lastname: Nozawa
authors.forename: K
authors.initials: K
authors.lastname: Sasaki
mesh_terms: D000818:Animals; D006084:Graft Rejection; D006965:Hyperplasia / Q000209:etiology / Q000473:pathology; D007082:Ileum / Q000473:pathology / Q000637:transplantation*; D007413:Intestinal Mucosa / Q000473:pathology / Q000637:transplantation*; D009336:Necrosis; D051381:Rats; D011917:Rats, Inbred Lew; D011919:Rats, Inbred Strains; D013997:Time Factors; D014184:Transplantation, Homologous; D014185:Transplantation, Isogeneic