title: Microencapsulation of propranolol hydrochloride by the solvent evaporation technique.
abstract: Propranolol hydrochloride microcapsules were prepared by the coacervation-phase separation induced by solvent evaporation technique. The cellulose acetate phthalate was employed as coating material alone and in combination with ethyl cellulose. The prepared microcapsules were evaluated for their drug content, particle size distribution (microscopic method), flow properties, bulk density, in vitro dissolution and drug release kinetics.
authors.affiliation: Department of Pharmaceutical Sciences, Nagpur University, India.
authors.forename: N C
authors.initials: NC
authors.lastname: Manekar
authors.forename: P K
authors.initials: PK
authors.lastname: Puranik
authors.forename: S B
authors.initials: SB
authors.lastname: Joshi
mesh_terms: D002482:Cellulose / Q000031:analogs & derivatives / Q000737:chemistry; D004339:Drug Compounding / Q000379:methods*; D007700:Kinetics; D011433:Propranolol / Q000008:administration & dosage*; D012997:Solvents / Q000737:chemistry; D014835:Volatilization
chemical_list: D012997:Solvents; C013517:ethyl cellulose; D002482:Cellulose; C011708:cellulose acetate phthalate; D011433:Propranolol