title: Serous otitis media and paranasopharyngeal extension of nasopharyngeal carcinoma.
abstract: Two hundred thirty-two patients with nasopharyngeal carcinoma were evaluated for serous otitis media (SOM) at diagnosis. The diagnosis of SOM required the detection of effusion behind the tympanic membrane in association of air-bone gap of 10 dB or more in pure tone audiogram. These patients were also evaluated by computed tomography for the degree of tumor extension. By stepwise logistic regression analysis, the degree of paranasopharyngeal extension of tumor, erosion of petrous temporal bone, and the obliteration of pharyngeal recess were significantly related to the development of SOM, but sex and age were not. The findings of computed tomography may influence the plan of management for SOM in patients with nasopharyngeal carcinoma at diagnosis.
authors.affiliation: Department of Radiotherapy and Oncology, University of Hong Kong, Queen Mary Hospital.
authors.forename: J S
authors.initials: JS
authors.lastname: Sham
authors.forename: W I
authors.initials: WI
authors.lastname: Wei
authors.forename: S K
authors.initials: SK
authors.lastname: Lau
authors.forename: C C
authors.initials: CC
authors.lastname: Yau
authors.forename: D
authors.initials: D
authors.lastname: Choy
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D009367:Neoplasm Staging; D010034:Otitis Media with Effusion / Q000209:etiology*; D011446:Prospective Studies; D012886:Skull / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed