Patterning of retinotectal connections in the vertebrate visual system.
Recent work on the retinotectal projection clearly establishes the roles of neuronal activity and position-based cues in the patterning of nerve connections. In some species, the high degree of spatial order has been shown to emerge from a continued process of terminal growth and refinement. The future challenge is now to determine how multiple cues work together to guide the sculpting of the final pattern.
Fraser
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Division of Biology, Beckman Institute, Pasadena, California 91125.
D000818:Animals; D006801:Humans; D009434:Neural Pathways / Q000502:physiology*; D012160:Retina / Q000166:cytology / Q000502:physiology*; D013477:Superior Colliculi / Q000166:cytology / Q000502:physiology*; D014785:Vision, Ocular / Q000502:physiology*