title: A patient with Werner's syndrome and osteosarcoma presenting as scleroderma.
abstract: Werner's syndrome (WS) is often mistaken for scleroderma. We describe a patient with WS who presented with an enlarging, painful mass of the right knee that proved to be a juxtaarticular osteosarcoma of the distal femur. Recognition of WS and prompt investigation of any painful, enlarging masses to exclude sarcomatous degeneration will benefit these patients.
authors.affiliation: Department of Medicine, Sunnybrook Health Science Centre, University of Toronto, ON, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Khraishi
authors.forename: B
authors.initials: B
authors.lastname: Howard
authors.forename: H
authors.initials: H
authors.lastname: Little
mesh_terms: D001859:Bone Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008875:Middle Aged; D012516:Osteosarcoma / Q000175:diagnosis* / Q000000981:diagnostic imaging; D011859:Radiography; D012595:Scleroderma, Systemic / Q000175:diagnosis*; D014898:Werner Syndrome / Q000175:diagnosis*