title: Dialysis in patients with upper urinary tract transitional cell carcinoma.
abstract: In some patients with primary malignant disease of the kidney the only way of achieving a cure may involve radical surgery. If the tumour is bilateral or involves a solitary kidney, renal failure may be unavoidable. The role of dialysis and transplantation in these patients following "curative" cancer surgery is not clear. A review of the literature and experience with 4 patients who ultimately had bilateral nephrectomies for multiple recurrent upper tract urothelial malignancy is reported. These 4 patients remained free of tumour recurrence on dialysis at 5, 8, 12 and 72 months respectively since commencing dialysis, although 2 have died from unrelated causes. It would seem reasonable to offer dialysis followed by subsequent transplantation in this group of patients after a period of 1 to 2 years has elapsed without any evidence of malignant recurrence.
authors.affiliation: Department of Urology, Royal Infirmary Hospital, Bristol.
authors.forename: R A
authors.initials: RA
authors.lastname: Persad
authors.forename: D A
authors.initials: DA
authors.lastname: Gillatt
authors.forename: P
authors.initials: P
authors.lastname: Harrison
authors.forename: P H
authors.initials: PH
authors.lastname: Abrams
mesh_terms: D000328:Adult; D002295:Carcinoma, Transitional Cell / Q000601:surgery*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000628:therapy*; D007680:Kidney Neoplasms / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009392:Nephrectomy / Q000009:adverse effects*; D011183:Postoperative Complications / Q000628:therapy*; D006435:Renal Dialysis; D014513:Ureter / Q000601:surgery; D014516:Ureteral Neoplasms / Q000601:surgery*