title: Intracranial meningiomas in patients over 70 years old. Follow-up in operated and unoperated cases.
abstract: Forty-six cases of intracranial meningioma in patients above 70 years of age form the basis of this study; 34 underwent surgery while 12 did not. The decision to operate was based on the general condition of the patient, evaluated according to the Karnofsky index, neurological conditions, the site and dimensions of the tumor, and the presence of peritumoral edema. The post-surgical mortality rate was 11.5% at 30 days, and 20% at 3 months. Long-term follow-up in both patient groups ranged from 1 to 5 years, and quality of life was evaluated by the Karnofsky index. Five operated patients died during follow-up (only 1 from intracranial pathology); the 22 survivors showed further improvement in their grading level compared to scores immediately following surgery. Among the unoperated patients, 6 died within two years of diagnosis, all from causes related to intracranial pathology; among the survivors, the Karnofsky index was unchanged in 2, and diminished in the other 4 cases.
authors.affiliation: Institute of Neurosurgery, University of Milano, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Arienta
authors.forename: M
authors.initials: M
authors.lastname: Caroli
authors.forename: S
authors.initials: S
authors.lastname: Balbi
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000150:complications / Q000601:surgery*; D004487:Edema / Q000150:complications; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000150:complications / Q000601:surgery*; D008579:Meningioma / Q000150:complications / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology; D011379:Prognosis; D011788:Quality of Life