An analysis of lectin agglutination as a means of sub-dividing gonococcal serovars.
Sixteen lectins were examined for their ability to agglutinate 298 strains of Neisseria gonorrhoeae. Seven lectins failed to agglutinate any of the strains; the remaining nine lectins gave 22 different agglutination patterns. The 298 strains were divided into 14 serovars with a single panel of monoclonal antibody typing reagents; lectin agglutination subdivided these into 57 serovar/lectin patterns. A combination of two monoclonal antibody serotyping panels divided the strains into 32 serovar combinations; lectin agglutination further subdivided these into 79 serovar/lectin patterns. There was no correlation between lectin pattern and serovar. Lectin agglutination is a simple supplementary typing method and could be particularly useful in micro-epidemiological studies.
Moyes
A
A
Department of Medical Microbiology, University of Edinburgh Medical School.
Young
H
H
D000371:Agglutination; D000372:Agglutination Tests; D006069:Gonorrhea / Q000382:microbiology; D006801:Humans; D037102:Lectins / Q000378:metabolism*; D009344:Neisseria gonorrhoeae / Q000145:classification* / Q000378:metabolism; D012703:Serotyping
D037102:Lectins