title: [Gene-enzyme system of alcohol dehydrogenase and adaptation of Drosophila to increased temperature].
abstract: Properties and allelic ADH (alcohol dehydrogenase) control in Drosophila melanogaster were studied upon flies' cultivation under conditions of hypotherm of different intensity and duration. Lines homozygotic for F allele (vg) and S allele (cn) of the Adh gene as well as genetically enriched experimental cn' and vg' populations containing a small number of AdhF/AdhS heterozygotes at the initial stage were used. It was found out that physiological adaptation of the species to momentary influence of elevated temperature is accompanied by modification of physical properties of ADH-F according to ADH-S. Constant influence (during the life span of 25 generations) of elevated temperature on the population changes its genetic structure, due to selective advantages of the S allele of Adh under these conditions.
authors.forename: N D
authors.initials: ND
authors.lastname: Khaustova
authors.forename: V M
authors.initials: VM
authors.lastname: Totskiĭ
authors.forename: N A
authors.initials: NA
authors.lastname: Strel'tsova
mesh_terms: D000222:Adaptation, Physiological; D000426:Alcohol Dehydrogenase / Q000235:genetics* / Q000378:metabolism; D000818:Animals; D004331:Drosophila melanogaster / Q000201:enzymology* / Q000502:physiology; D004795:Enzyme Stability; D006579:Heterozygote; D006358:Hot Temperature; D007527:Isoenzymes / Q000235:genetics* / Q000378:metabolism
chemical_list: D007527:Isoenzymes; D000426:Alcohol Dehydrogenase
vernacular_title: Gen-énzimnaia sistema alkogol'degidrogenazy i adaptatsiia drosofily k povyshennoĭ temperature.