Use of oocytes from anonymous, matched, fertile donors for prevention of heritable genetic diseases.
Heritable genetic diseases can be prevented with the use of donor oocytes. We report our experience in using donor oocytes from anonymous, matched, fertile donors in four women with heritable genetic disorders. Our results show that use of donor oocytes is a practical, successful, and currently available technique for the prevention of genetic disorders.
Van Voorhis
B J
BJ
Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, Iowa City 52242.
Williamson
R A
RA
Gerard
J L
JL
Hammitt
D G
DG
Syrop
C H
CH
D000328:Adult; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D030342:Genetic Diseases, Inborn / Q000517:prevention & control*; D006801:Humans; D009865:Oocytes; D014019:Tissue Donors