title: Relationship of symptomatology of schizophrenia and tardive dyskinesia.
abstract: The role of drug factors and patient factors in the development of tardive dyskinesia (TD) was examined in 31 TD patients and 31 non-TD patients matched by age and sex. TD patients achieved significantly lower total scores on the anxiety-depression factor of Brief Psychiatric Rating Scale (BPRS) (5.2 +/- 1.4 vs. 6.5 +/- 2.2; less than P) and significantly higher total scores on the activation factor (6.4 +/- 2.2 vs. 5.3 +/- 2.5; less than P). The finding that TD patients were less depressed may be explained by a hypermonoaminergic state developing in TD. Based on the findings of this study it is suggested that catatonic schizophrenic patients are more vulnerable to the development of TD.
authors.affiliation: National Institute for Nervous and Mental Diseases, Budapest, Hungary.
authors.forename: A
authors.initials: A
authors.lastname: Perenyi
authors.forename: T
authors.initials: T
authors.lastname: Norman
authors.forename: G D
authors.initials: GD
authors.lastname: Burrows
mesh_terms: D000293:Adolescent; D000328:Adult; D015306:Biogenic Monoamines / Q000097:blood; D003863:Depression / Q000150:complications / Q000523:psychology; D004409:Dyskinesia, Drug-Induced / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000150:complications*; D012565:Schizophrenic Psychology
chemical_list: D015306:Biogenic Monoamines