On the perfluorocarbon emulsions of second generation.
For formulation of perfluorocarbon-emulsions (PFC-emulsions) of second generation new perfluorocarbons (F-dimorpholines, F-dipiperidines and F-cyclohexylmorpholine) were synthesized, acting both as oxygen carriers and as interfacial active compounds (IFACs). The stabilizing effect of these IFACs is interpreted and a new theory is introduced. Also new classes of fluorosurfactants were synthesized and tested for biocompatibility. In PFC mixtures compounds of the type RFRH (RF = CmF2m + 1, RH = CnH2n + 1) are acting as IFACs but also as anchor-groups for lipophilic surfactants.
Meinert
H
H
Universität Ulm, Abt. Anorganische Chemie, Federal Republic of Germany.
Fackler
R
R
Knoblich
A
A
Mader
J
J
Reuter
P
P
Röhlke
W
W
D001672:Biocompatible Materials / Q000737:chemistry; D001802:Blood Substitutes / Q000138:chemical synthesis*; D004655:Emulsions / Q000737:chemistry; D005466:Fluorocarbons / Q000737:chemistry*; D008958:Models, Molecular; D009025:Morpholines / Q000737:chemistry; D010880:Piperidines / Q000737:chemistry; D013501:Surface-Active Agents / Q000737:chemistry
D001672:Biocompatible Materials; D001802:Blood Substitutes; D004655:Emulsions; D005466:Fluorocarbons; D009025:Morpholines; D010880:Piperidines; D013501:Surface-Active Agents