Sequence and variability of the 5.8S and 26S rRNA genes of Pneumocystis carinii.
The sequence of the coding region of the rRNA operon of rat-derived Pneumocystis carinii has been completed, including the genes for 5.8S and 26S rRNA. These genes show homology to the rRNA genes of yeast, and an apparent group I self-splicing intron is present in the 26S rRNA gene. Like a similar intron in the 16S rRNA gene, this intron is in a phylogenetically conserved region. Variation in the 26S rRNA sequence was noted between P. carinii organisms isolated from two different sources.
Liu
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Department of Molecular Genetics and Microbiology, UMDNJ--Robert Wood Johnson Medical School, Piscataway 08854-5635.
Rocourt
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Pan
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Liu
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Leibowitz
M J
MJ
D001483:Base Sequence; D003001:Cloning, Molecular; D005800:Genes, Fungal; D007438:Introns / Q000235:genetics; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D009876:Operon / Q000235:genetics; D011010:Pneumocystis / Q000235:genetics*; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic / Q000235:genetics; D016337:RNA, Catalytic / Q000235:genetics; D012331:RNA, Fungal / Q000235:genetics; D012335:RNA, Ribosomal / Q000235:genetics*; D012340:RNA, Ribosomal, 5.8S / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid
D016337:RNA, Catalytic; D012331:RNA, Fungal; D012335:RNA, Ribosomal; D012340:RNA, Ribosomal, 5.8S; C065096:RNA, ribosomal, 26S