Sex differentiation: the role of alternative splicing.
Sex differentiation in Drosophila is controlled by a regulatory cascade with at least three regulated alternative RNA-processing events. The results of recent work have verified much of the earlier molecular and genetic work in this field and have provided a demonstration that both positive and negative regulatory mechanisms are involved.
McKeown
M
M
Molecular Biology and Virology Laboratory, Salk Institute, San Diego, California 92186.
D000818:Animals; D001483:Base Sequence; D004330:Drosophila / Q000196:embryology* / Q000235:genetics; D005809:Genes, Regulator / Q000502:physiology*; D008969:Molecular Sequence Data; D012326:RNA Splicing / Q000502:physiology*; D012733:Sex Differentiation / Q000235:genetics