Protease resistant interleukin-3 stimulating components in excretory and secretory products from adult worms of Strongyloides ratti.
Excretory and secretory (ES) products collected from adult worms of Strongyloides ratti stimulated interleukin-3 (IL-3) production with mesenteric lymph node cells from infected C57BL/6 mice, but not with normal mesenteric lymph node cells. The IL-3 stimulating components were not major IgG binding antigens. Activity of the IL-3 stimulating components was stable by treatment with protease, although reduced by heating in boiling water.
Abe
T
T
Department of Parasitology, Akita University School of Medicine, Japan.
Nawa
Y
Y
Yoshimura
K
K
D000818:Animals; D002478:Cells, Cultured; D002851:Chromatography, High Pressure Liquid; D010450:Endopeptidases / Q000378:metabolism; D006358:Hot Temperature; D007377:Interleukin-3 / Q000276:immunology*; D008198:Lymph Nodes / Q000166:cytology / Q000276:immunology*; D051379:Mice; D008810:Mice, Inbred C57BL; D013321:Strongyloides / Q000276:immunology*
D007377:Interleukin-3; D010450:Endopeptidases