Effects of chronic administration of noradrenaline and glucagon on in vitro brown adipose tissue thermogenesis.
The in vitro brown adipose tissue (BAT) oxygen consumption stimulated by noradrenaline (NA) or glucagon (G) was significantly lower in chronically NA-treated rats and that of G-treated rats did not differ as compared with that of vehicle-treated control animals. In vitro thermogenic response of BAT in NA-treated rats was consistent with that induced by cold acclimation.
Kikuchi
K
K
Department of Physiology I, Asahikawa Medical College, Japan.
Okano
S
S
Nozu
T
T
Yahata
T
T
Kuroshima
A
A
D000064:Acclimatization / Q000502:physiology; D002001:Adipose Tissue, Brown / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D001833:Body Temperature Regulation / Q000187:drug effects / Q000502:physiology*; D005934:Glucagon / Q000494:pharmacology / Q000502:physiology; D066298:In Vitro Techniques; D008297:Male; D009638:Norepinephrine / Q000494:pharmacology / Q000502:physiology; D010101:Oxygen Consumption / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains
D005934:Glucagon; D009638:Norepinephrine