Organic mood disorder associated with the HAIR-AN syndrome.
The HAIR-AN syndrome is characterized by hyperandrogenism, insulin resistance, and acanthosis nigricans. The authors report the first case of an organic mood disorder associated with this condition that improved markedly in response to ovarian suppression with oral contraceptives. The proposed pathophysiology of this syndrome is also discussed.
Levin
T R
TR
Medical Psychiatric Unit, Emory University Hospital, Atlanta, GA.
Terrell
T R
TR
Stoudemire
A
A
D000052:Acanthosis Nigricans / Q000503:physiopathology* / Q000523:psychology; D000328:Adult; D000728:Androgens / Q000097:blood*; D003276:Contraceptives, Oral / Q000008:administration & dosage; D003866:Depressive Disorder / Q000503:physiopathology* / Q000523:psychology; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007333:Insulin Resistance / Q000502:physiology*; D019965:Neurocognitive Disorders / Q000503:physiopathology* / Q000523:psychology; D009483:Neuropsychological Tests; D011085:Polycystic Ovary Syndrome / Q000503:physiopathology* / Q000523:psychology
D000728:Androgens; D003276:Contraceptives, Oral; D012739:Gonadal Steroid Hormones; D006854:Hydrocortisone