Hepatitis E virus: the cause of a waterbourne hepatitis outbreak.
Newly developed assays for antibody to hepatitis E virus (HEV) were used to study 114 serum samples collected during an outbreak of enterically transmitted hepatitis that occurred in Kashmir in 1978/9. The sera included samples from patients with viral hepatitis, anicteric hepatitis, contacts of cases, and unaffected persons. A total of 71% of patients with viral hepatitis were found positive for anti-HEV specific IgG, and 75% of these were also positive for IgM. These data confirm the hepatitis E virus as the causative agent in this outbreak.
Skidmore
S J
SJ
Regional Virus Laboratory, East Birmingham Hospital, United Kingdom.
Yarbough
P O
PO
Gabor
K A
KA
Reyes
G R
GR
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004196:Disease Outbreaks; D004797:Enzyme-Linked Immunosorbent Assay; D006508:Hepatitis Antibodies / Q000097:blood*; D016751:Hepatitis E / Q000453:epidemiology*; D016752:Hepatitis E virus / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007194:India / Q000453:epidemiology; D008875:Middle Aged; D016036:Seroepidemiologic Studies
D006508:Hepatitis Antibodies; D007074:Immunoglobulin G; D007075:Immunoglobulin M