Age-related changes of the branched-chain fatty acid concentration in rat skin surface lipid.
1. Age-related change of the branched-chain fatty acid distribution in rat skin surface lipid was studied for 24 months. 2. The proportion of even carbon number iso-acid increased from infancy to month 5 and thereafter decreased with advancing age toward senescence. 3. Concentration of odd carbon number iso-acid depicted a similar shape of time course, but with a lesser magnitude and a peak value at month 1. 4. Anteiso- fatty acid reached the plateau level at month 5 and remained roughly constant through maturity to senescence.
Oku
H
H
Laboratory of Applied Biochemistry, Faculty of Agriculture, University of the Ryukyus, Okinawa, Japan.
Oohama
E
E
Yagi
N
N
Urahashi
A
A
Nagata
J
J
Shinjyo
C
C
Chinen
I
I
D000375:Aging / Q000097:blood / Q000378:metabolism*; D000597:Amino Acids, Branched-Chain / Q000097:blood; D000818:Animals; D002855:Chromatography, Thin Layer; D005227:Fatty Acids / Q000097:blood / Q000737:chemistry / Q000378:metabolism*; D007700:Kinetics; D050356:Lipid Metabolism; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012867:Skin / Q000378:metabolism*
D000597:Amino Acids, Branched-Chain; D005227:Fatty Acids