title: Postoperative pulmonary function abnormalities after coronary artery bypass surgery.
abstract: In 18 patients, postoperative effects of coronary bypass surgery were evaluated. Pulmonary function studies were conducted preoperatively, and 1 and 6 weeks postoperatively, by means of spirometry, respiratory pressures, body plethysmography and impedance measurement of the respiratory system using the forced oscillation technique. One week postoperatively, total lung capacity (P less than 0.0001), inspiratory vital capacity (P less than 0.0001) forced expiratory volume (P less than 0.0001) and functional residual capacity (P less than 0.01) decreased significantly, while residual volume remained unchanged. This restrictive respiratory impairment was accompanied by significant decreases in inspiratory (P less than 0.0001) and expiratory (P less than 0.01) mouth pressures and significant decreases in respiratory resistance values (P less than 0.01). Six weeks postoperatively, significant differences in total lung capacity (P less than 0.0001), inspiratory vital capacity (P less than 0.0001) and forced expiratory volume (P less than 0.0001) persisted, while respiratory pressures returned to the preoperative values. It is concluded that respiratory muscle weakness contributes to the immediate postoperative restrictive lung function loss. Furthermore, structural alterations of chest wall mechanics have to be supposed for the persisting late restrictive pulmonary impairment.
authors.affiliation: Department of Pulmonary Diseases, University Hospital Maastricht, The Netherlands.
authors.forename: A F
authors.initials: AF
authors.lastname: van Belle
authors.forename: G J
authors.initials: GJ
authors.lastname: Wesseling
authors.forename: O C
authors.initials: OC
authors.lastname: Penn
authors.forename: E F
authors.initials: EF
authors.lastname: Wouters
mesh_terms: D000328:Adult; D000368:Aged; D001026:Coronary Artery Bypass; D005260:Female; D005541:Forced Expiratory Volume; D005652:Functional Residual Capacity; D006801:Humans; D007320:Inspiratory Capacity; D008168:Lung / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D012115:Residual Volume; D014109:Total Lung Capacity