Antidromic and synaptic activation of Deiters' neurons induced by stimulation of red nucleus in the cat.
Antidromic and orthodromic action potentials of neurons located in the lateral vestibular nucleus of Deiters' evoked by stimulation of red nucleus were studied in anaesthetized cats. Vestibulospinal neurons were identified by stimulation of the lateral vestibulospinal tract. The 'second-order' vestibular neurons were revealed by mean of stimulation of the ipsilateral VIIIth nerve. Stimulation of the red nucleus is shown to lead mainly to antidromic, as well as mono-, oligo- and polysynaptic activation of Deiters' neurons. Not any inhibitory reaction was observed in vestibular neurons in response to stimulation of the red nucleus. Ascending axon collaterals of the vestibulospinal neurons to this brainstem structure were revealed. The peculiarities and functional significance of the effects mentioned are discussed.
Sarkisian
V H
VH
Laboratory of Physiology of Central Nervous System, Orbeli Institute of Physiology, Academy of Sciences of Armenia, Yerevan.
Fanardjian
V V
VV
D000200:Action Potentials; D000344:Afferent Pathways / Q000502:physiology; D000818:Animals; D002415:Cats; D004558:Electric Stimulation; D009474:Neurons / Q000502:physiology; D012012:Red Nucleus / Q000502:physiology*; D014725:Vestibular Nerve / Q000502:physiology; D003689:Vestibular Nucleus, Lateral / Q000166:cytology / Q000502:physiology*