title: Lymphocyte interactions with endothelial cells.
abstract: Adhesion of lymphocytes to endothelium is vital to lymphocyte migration into lymphoid tissue and into inflammatory sites. In this review, Yoji Shimizu and colleagues identify the molecules that mediate lymphocyte-endothelial cell adhesion, describe the underlying principles of lymphocyte migration, and discuss a model of the sequence of events that allow a lymphocyte to successfully attach to endothelium and migrate into the surrounding tissue.
authors.affiliation: Dept of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor 48109.
authors.forename: Y
authors.initials: Y
authors.lastname: Shimizu
authors.forename: W
authors.initials: W
authors.lastname: Newman
authors.forename: Y
authors.initials: Y
authors.lastname: Tanaka
authors.forename: S
authors.initials: S
authors.lastname: Shaw
mesh_terms: D015815:Cell Adhesion Molecules / Q000502:physiology*; D002465:Cell Movement / Q000502:physiology; D004730:Endothelium, Vascular / Q000166:cytology*; D006801:Humans; D013601:T-Lymphocytes / Q000502:physiology*
chemical_list: D015815:Cell Adhesion Molecules