Anti-lymphocyte antibodies generated in animals immunised with Theileria annulata-infected cells.
Complement fixing antibodies were measured in sera from animals immunised with either Theileria annulata sporozoites or autologous or allogeneic schizont-infected mononuclear cells using a complement-mediated micro-cytotoxicity test. The test demonstrated the presence of anti-lymphocyte antibodies in allogeneic cell-immunised animals, which were not detectable in autologous cell- or sporozoite-immunised animals; also that these antibodies were directed to T. annulata-infected and (MHC) class I antigens. Their potential importance in repeated immunisations is discussed.
Kachani
M
M
Département de Parasitologie, Institut Agronomique et Vétérinaire Hassan II, Rabat Instituts, Morocco.
Spooner
R L
RL
D000818:Animals; D000918:Antibody Specificity; D000961:Antilymphocyte Serum / Q000032:analysis / Q000096:biosynthesis*; D002417:Cattle; D007114:Immunization; D007963:Leukocytes, Mononuclear / Q000276:immunology / Q000469:parasitology; D016796:Theileria annulata / Q000254:growth & development / Q000276:immunology*; D013801:Theileriasis / Q000097:blood / Q000276:immunology* / Q000469:parasitology
D000961:Antilymphocyte Serum