Multiple occurrence of macro creatine kinase in one family.
We measured creatine kinase (CK, EC 2.7.3.2), CK-MB isoenzyme activity and mass concentration, and distribution of CK isoenzymes (by electrophoresis) in serum from five members of one family. The mother and two young children showed CK-IgG complexes in their sera. The concentration of the CK-IgG complexes in the children decreased over time, suggesting that the complex involved maternal IgG and had been transferred across the placenta from the mother to her children.
Bayer
P M
PM
Department of Clinical Chemistry and Laboratory Medicine, Wilhelminen Hospital, Vienna, Austria.
Kraus
S
S
D000328:Adult; D000936:Antigen-Antibody Complex / Q000097:blood*; D003402:Creatine Kinase / Q000097:blood* / Q000276:immunology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007223:Infant; D007231:Infant, Newborn; D007527:Isoenzymes
D000936:Antigen-Antibody Complex; D007074:Immunoglobulin G; D007527:Isoenzymes; D003402:Creatine Kinase