[Genetic markers of individual predisposition to lung cancer].
The investigation concerning the dependence of cancer incidence on genetic HLA-markers and character of dermatoglyphs was carried out. The use of the pattern recognition method for multifactorial estimation of the above markers as well as the elimination of the main non-genetic oncogenic risk factors allowed obtaining the proof of the existence of the genetic predisposition to lung cancer. It was estimated that the character of dermatoglyphic prints is the most adequate marker for the investigated predisposition, and the reliable prediction of the genetic risk of the lung cancer development can be given as based on the joint evaluation of both markers.
Polzik
E V
EV
Katsnel'son
B A
BA
Lezhnin
V L
VL
Iakusheva
M Iu
MIu
Khodyrev
V N
VN
D015984:Causality; D003878:Dermatoglyphics; D005819:Genetic Markers / Q000235:genetics; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology / Q000235:genetics*; D010363:Pattern Recognition, Automated; D012307:Risk Factors
D005819:Genetic Markers; D006680:HLA Antigens
K probleme geneticheskikh markerov individual'noĭ predraspolozhennosti k raku legkikh.