Evaluation of serum ferritin as a marker for adult Still's disease activity.
Extremely high serum ferritin values (greater than 10,000 micrograms/l) were detected in two patients with adult Still's disease. The ferritin concentrations decreased to normal after adequate treatment. During a one year follow up ferritin concentration was helpful in monitoring disease activity and guiding decisions about treatment. Raised concentrations of soluble interleukin 2 receptors (sCD25) were also found. Detection of ferritin values above 3000 micrograms/l should lead to the consideration of Still's disease when there is an acute febrile illness without evidence for bacterial or viral infections, serum ferritin being suitable for monitoring treatment.
Schwarz-Eywill
M
M
Department of Internal Medicine, Med Poliklink V, University of Heidelberg, Germany.
Heilig
B
B
Bauer
H
H
Breitbart
A
A
Pezzutto
A
A
D000328:Adult; D015415:Biomarkers / Q000097:blood; D005260:Female; D005293:Ferritins / Q000097:blood*; D006801:Humans; D008297:Male; D016706:Still's Disease, Adult-Onset / Q000097:blood* / Q000175:diagnosis
D015415:Biomarkers; D005293:Ferritins