title: Pain mechanisms and the management of neuropathic pain.
abstract: The nociceptive system is not fixed, but changes in response to its input and activity. This 'plasticity' comprises dynamic developments of both pro- and antinociceptive processes. Recent advances in the understanding of these processes have important implications for the treatment of persistent neuropathic pain.
authors.affiliation: Sir Humphry Davy Department of Anaesthesia, Bristol Royal Infirmary, UK.
authors.forename: J
authors.initials: J
authors.lastname: Alexander
authors.forename: A
authors.initials: A
authors.lastname: Black
mesh_terms: D000344:Afferent Pathways / Q000503:physiopathology; D000700:Analgesics / Q000627:therapeutic use; D005727:Ganglia, Spinal / Q000503:physiopathology; D006801:Humans; D009437:Neuralgia / Q000503:physiopathology* / Q000628:therapy; D009473:Neuronal Plasticity / Q000502:physiology*; D009474:Neurons / Q000502:physiology; D009619:Nociceptors / Q000503:physiopathology*; D010525:Peripheral Nerves / Q000503:physiopathology
chemical_list: D000700:Analgesics