title: Convergent solid-phase peptide synthesis IX: application to the synthesis of peptides with repetitive sequences.
abstract: The synthesis of a 36 amino acid peptide containing six conserved repeats of Val-His-Leu-Pro-Pro-Pro which corresponds to the glutelin-2 protein of maize has been carried out using a convergent approach. The protected single sequence repeat has been synthesized using a combination of a 9-fluorenylmethyloxycarbonyl (Fmoc) protection scheme and a p-alkoxybenzyl resin. The final peptide, as well as the different intermediate peptides, has been characterized by fast atom bombardment mass spectrometry (FAB-MS) and by co-elution with another sample obtained by stepwise continuous flow synthesis.
authors.affiliation: Departament de Química Orgànica, Universitat de Barcelona, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Celma
authors.forename: F
authors.initials: F
authors.lastname: Albericio
authors.forename: E
authors.initials: E
authors.lastname: Pedroso
authors.forename: E
authors.initials: E
authors.lastname: Giralt
mesh_terms: D000595:Amino Acid Sequence; D002851:Chromatography, High Pressure Liquid; D008401:Gas Chromatography-Mass Spectrometry; D005983:Glutens / Q000138:chemical synthesis*; D008969:Molecular Sequence Data; D010455:Peptides / Q000138:chemical synthesis*; D010940:Plant Proteins
chemical_list: D010455:Peptides; D010940:Plant Proteins; D005983:Glutens; C067781:Zc2 protein, Zea mays