Massive ascites after leuprolide acetate administration for the treatment of leiomyomata uteri.
The administration of GnRH-a for decreasing the size of uterine leiomyomata is tolerated by most of our patients with a minimum of side effects and difficulty. An unusual case of pseudo-Meigs' syndrome developed after a single dose of depot LA that resulted in an emergent operation in this young woman. The treatment of large leiomyomata uteri with GnRH-a warrants careful clinical surveillance.
Lee
M J
MJ
Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinois 60611.
Kazer
R R
RR
D000328:Adult; D001201:Ascites / Q000139:chemically induced*; D001202:Ascitic Fluid / Q000473:pathology; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000188:drug therapy* / Q000473:pathology; D016729:Leuprolide / Q000009:adverse effects* / Q000627:therapeutic use; D009929:Organ Size; D014594:Uterine Neoplasms / Q000188:drug therapy* / Q000473:pathology; D014599:Uterus / Q000473:pathology
D016729:Leuprolide