title: Current research in side effects of high-dose chemotherapy.
abstract: The toxicities of chemotherapy continue to hamper dose escalation of specific chemotherapeutic agents. The impact of dose intensification upon survival will be assessed as clinical studies continue. Strategies to support chemotherapy dose intensification include BMT, use of CSFs and antiemetic drug combinations. Advances in symptom management will hopefully enhance quality of life for patients, whereas the development of chemoprotectant agents may allow specific organ toxicities to be avoided.
authors.affiliation: Department of Nursing, Vanderbilt University Medical Center, Nashville, TN 37232-2410.
authors.forename: D
authors.initials: D
authors.lastname: Wujcik
mesh_terms: D000970:Antineoplastic Agents / Q000633:toxicity*; D003556:Cystitis / Q000139:chemically induced; D005767:Gastrointestinal Diseases / Q000139:chemically induced; D006331:Heart Diseases / Q000139:chemically induced; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced; D009422:Nervous System Diseases / Q000139:chemically induced; D009859:Oncology Nursing; D012106:Research
chemical_list: D000970:Antineoplastic Agents