A fast gradient-recalled MRI technique with increased sensitivity to dynamic susceptibility effects.
A fast imaging method that is based on gradient-recalled echoes of spins whose excitation and echo formation are separated by more than one TR period is presented. This method does not incorporate chemical-shift refocusing and thus results in drastically increased sensitivity to dynamic susceptibility effects, while maintaining a short total imaging time. The efficiency of the new technique is demonstrated in dynamic contrast-enhanced experiments (bolus tracking) in the cat brain using a duration of 600 ms for each image. Blood volume maps are derived with expected contrast between white and gray matter.
Moonen
C T
CT
NMR Research Center, BEIP, NCRR, National Institutes of Health, Bethesda, Maryland 20892.
Liu
G
G
van Gelderen
P
P
Sobering
G
G
D000818:Animals; D001921:Brain / Q000033:anatomy & histology*; D002415:Cats; D003287:Contrast Media; D019786:Gadolinium DTPA; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009942:Organometallic Compounds; D004369:Pentetic Acid; D013997:Time Factors
D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA