[Changes in the form and ultrastructure of the smooth-muscle cells in the human aorta in prenatal ontogeny].
The shape of smooth muscle cells (SMC) was analysed using the phase contrast microscopy of cell suspensions obtained by alcohol-alkali dissociation, as well as the semithin sections prepared in perpendicular planes. The phenotype of SMC was analysed using transmission electron microscopy. The shape of SMC changes from preferentially round to preferentially spindle-like and stellate one during development. The differentiation of SMC is accompanied with the increase in the contractile apparatus content and in the decrease in the content of synthetic organelles.
Rekhter
M D
MD
Kolpakov
V A
VA
Korobkina
K Iu
KIu
Kovaleva
T V
TV
Peretiatko
L P
LP
Kulida
L V
LV
Mironov
A A
AA
D008841:Actin Cytoskeleton / Q000648:ultrastructure; D001011:Aorta / Q000196:embryology / Q000648:ultrastructure; D002454:Cell Differentiation; D003584:Cytological Techniques; D003593:Cytoplasm / Q000648:ultrastructure; D005865:Gestational Age; D006801:Humans; D008854:Microscopy, Electron; D008858:Microscopy, Phase-Contrast; D009131:Muscle, Smooth, Vascular / Q000196:embryology / Q000648:ultrastructure*
Izmenenie formy i ul'trastruktury gladkomyshechnykh kletok aorty cheloveka v prenatal'nom periode.