title: HbH disease associated with the (--MED) deletion in a Brazilian black woman.
abstract: Clinical, laboratory features and restriction enzyme DNA analysis are reported for a black Brazilian woman with HbH disease. The patient presented a thalassemic blood picture with HbH and Hb Bart's. Gene mapping demonstrated the compound heterozygous state for the --MED and -alpha 3.7 deletions.
authors.affiliation: Department of Clinical Pathology, School of Medicine, State University of Campinas, Brazil.
authors.forename: M F
authors.initials: MF
authors.lastname: Sonati
authors.forename: E M
authors.initials: EM
authors.lastname: Kimura
authors.forename: H Z
authors.initials: HZ
authors.lastname: Grotto
authors.forename: M H
authors.initials: MH
authors.lastname: Tavella
authors.forename: F F
authors.initials: FF
authors.lastname: Costa
mesh_terms: D000328:Adult; D044383:Black People / Q000235:genetics*; D001938:Brazil; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D004247:DNA / Q000032:analysis; D005260:Female; D005914:Globins / Q000235:genetics; D006579:Heterozygote; D006801:Humans; D015183:Restriction Mapping; D013789:Thalassemia / Q000235:genetics*
chemical_list: D005914:Globins; D004247:DNA