title: Changing trends in the epidemiology and management of gonococcal ophthalmia neonatorum.
abstract: Between June 1985 and December 1988, 58 cases of gonococcal ophthalmia neonatorum were admitted to the neonatal unit at the University Hospital (USM). Of these, 15 (25.9%) cases were due to penicillin-resistant strains of Neisseria gonorrhoea. Of the 58 cases, 56 cases were treated effectively with a single dose of antibiotic given systemically. The mean period of recovery was shorter with spectinomycin in doses of 40 mg/kg than with cefotaxime (100 mg/kg). There was no permanent sequelae in the treated cases. An increasing incidence of infection with penicillin-resistant strains of N. gonorrhoea has been observed in the area of study.
authors.affiliation: Department of Paediatrics, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kelantan.
authors.forename: A K
authors.initials: AK
authors.lastname: Gururaj
authors.forename: W A
authors.initials: WA
authors.lastname: Ariffin
authors.forename: S
authors.initials: S
authors.lastname: Vijayakumari
authors.forename: T N
authors.initials: TN
authors.lastname: Reddy
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D009878:Ophthalmia Neonatorum / Q000188:drug therapy* / Q000453:epidemiology; D012846:Singapore / Q000453:epidemiology