title: IgA producing primary intracerebral lymphoma.
abstract: The first case of a primary and solitary IgA (lambda) producing tumour (possibly a non-Hodgkin's lymphoma) in the CNS is reported. Clinical and neuroimaging findings are described. Early diagnosis without brain biopsy and successful therapy were possible by CSF and serum immunoglobulin analysis which proved local paraprotein production restricted to the CNS.
authors.affiliation: Department of Neurology, University of Goettingen, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Burkhardt
authors.forename: H I
authors.initials: HI
authors.lastname: Schipper
authors.forename: U
authors.initials: U
authors.lastname: Kaboth
authors.forename: K
authors.initials: K
authors.lastname: Felgenhauer
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000134:cerebrospinal fluid*; D007146:Immunoglobulin lambda-Chains / Q000134:cerebrospinal fluid*; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy; D014057:Tomography, X-Ray Computed
chemical_list: D000305:Adrenal Cortex Hormones; D007070:Immunoglobulin A; D007146:Immunoglobulin lambda-Chains