Time course EPI of human brain function during task activation.
Using gradient-echo echo-planar MRI, a local signal increase of 4.3 +/- 0.3% is observed in the human brain during task activation, suggesting a local decrease in blood deoxyhemoglobin concentration and an increase in blood oxygenation. Images highlighting areas of signal enhancement temporally correlated to the task are created.
Bandettini
P A
PA
Department of Radiology, Medical College of Wisconsin, Milwaukee 53226.
Wong
E C
EC
Hinks
R S
RS
Tikofsky
R S
RS
Hyde
J S
JS
D001921:Brain / Q000502:physiology*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D013647:Task Performance and Analysis
D006454:Hemoglobins; C100003:deoxyhemoglobin; D010100:Oxygen