High-performance liquid chromatographic determination of alpha-tocopheryl nicotinate in cosmetic preparations.
alpha-Tocopheryl nicotinate (alpha-TN) accelerates blood circulation and stimulates hair follicle cells, hence it is an active ingredient in a broad range of cosmetic products. A reversed-phase high-performance liquid chromatographic method was developed to determine alpha-TN in cosmetic preparations with alpha-tocopheryl acetate as internal standard. The method was found to be rapid, precise and specific.
Baruffini
A
A
Department of Pharmaceutical Chemistry, Pavia, Italy.
De Lorenzi
E
E
Gandini
C
C
Kitsos
M
M
Massolini
G
G
D002851:Chromatography, High Pressure Liquid; D003358:Cosmetics / Q000032:analysis*; D009539:Nicotinic Acids / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet; D014665:Vasodilator Agents / Q000032:analysis*; D014810:Vitamin E / Q000031:analogs & derivatives* / Q000032:analysis
D003358:Cosmetics; D009539:Nicotinic Acids; D014665:Vasodilator Agents; D014810:Vitamin E; C012581:alpha-tocopheryl nicotinate