Guidance of neuroblast migrations and axonal projections in Caenorhabditis elegans.
The nematode Caenorhabditis elegans provides an excellent model system in which to study the mechanisms involved in the development of the nervous system. Mutation analyses have now identified several genes that appear to be important in the interaction of neuroblasts and axons with both guidance cues and their target cells.
Wadsworth
W G
WG
Department of Biology, Johns Hopkins University, Baltimore, Maryland 21218.
Hedgecock
E M
EM
D000818:Animals; D001369:Axons / Q000502:physiology*; D002107:Caenorhabditis / Q000254:growth & development*; D002465:Cell Movement; D009420:Nervous System / Q000254:growth & development*; D009434:Neural Pathways / Q000166:cytology / Q000254:growth & development