title: Effects of enalapril on heart failure in hypertensive patients with diastolic dysfunction.
abstract: Ten hypertensive patients with symptoms of heart failure and normal systolic function but with diastolic dysfunction were treated with 10 mg enalapril twice a day for 9 +/- 3 months to evaluate the effects of this agent alone on heart failure induced by diastolic dysfunction. After therapy, all patients improved and echocardiographic parameters of diastolic dysfunction became normalized. It is concluded that enalapril appears to be useful in the treatment of heart failure in hypertensive patients with normal systolic function and diastolic dysfunction.
authors.affiliation: Department of Medicine, San Juan City Hospital, Puerto Rico University School of Medicine, Río Piedras.
authors.forename: R A
authors.initials: RA
authors.lastname: González-Fernández
authors.forename: P I
authors.initials: PI
authors.lastname: Altieri
authors.forename: L M
authors.initials: LM
authors.lastname: Díaz
authors.forename: P J
authors.initials: PJ
authors.lastname: Rodríguez
authors.forename: J
authors.initials: J
authors.lastname: Fernández
authors.forename: J G
authors.initials: JG
authors.lastname: Miranda
authors.forename: J
authors.initials: J
authors.lastname: Báez
authors.forename: D
authors.initials: D
authors.lastname: Cantellops
authors.forename: J E
authors.initials: JE
authors.lastname: Lugo
mesh_terms: D000328:Adult; D002303:Cardiac Output, Low / Q000188:drug therapy* / Q000209:etiology; D003971:Diastole; D004452:Echocardiography; D004656:Enalapril / Q000627:therapeutic use*; D005260:Female; D006321:Heart / Q000503:physiopathology*; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology; D008297:Male; D008875:Middle Aged
chemical_list: D004656:Enalapril