Different stabilities to bile among feline calicivirus strains of respiratory and enteric origin.
Feline calicivirus (FCV) strains isolated from feces (E-FCV) were compared with FCV strains of respiratory origin (R-FCV). All strains were shown to be labile at pH 3.0. All strains except one strain of E-FCV were found to be sensitive to the action of trypsin. When exposed to bile salt (deoxycholic acid sodium salt), all R-FCV strains were markedly inactivated, but none of the E-FCV strains was inactivated. It was possible to select bile-resistant substrains from a bile-sensitive strain.
Mochizuki
M
M
Department of Veterinary Medicine, Faculty of Agriculture, Kagoshima University, Japan.
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D001646:Bile / Q000378:metabolism*; D002139:Caliciviridae / Q000187:drug effects* / Q000276:immunology; D002371:Cat Diseases / Q000382:microbiology; D002415:Cats; D003168:Complement Fixation Tests; D003840:Deoxycholic Acid / Q000494:pharmacology*; D003967:Diarrhea / Q000382:microbiology / Q000662:veterinary; D005243:Feces / Q000382:microbiology*; D009500:Neutralization Tests; D012137:Respiratory System / Q000382:microbiology*; D012141:Respiratory Tract Infections / Q000382:microbiology / Q000662:veterinary
D000956:Antigens, Viral; D003840:Deoxycholic Acid