title: (E)-1,3-dialkyl-7-methyl-8-(3,4,5-trimethoxystyryl)xanthines: potent and selective adenosine A2 antagonists.
authors.affiliation: Pharmaceutical Research Laboratory, Kyowa Hakko Kogyo Co., Ltd, Shizuoka-ken Japan.
authors.forename: J
authors.initials: J
authors.lastname: Shimada
authors.forename: F
authors.initials: F
authors.lastname: Suzuki
authors.forename: H
authors.initials: H
authors.lastname: Nonaka
authors.forename: A
authors.initials: A
authors.lastname: Ishii
authors.forename: S
authors.initials: S
authors.lastname: Ichikawa
mesh_terms: D000241:Adenosine / Q000031:analogs & derivatives / Q000378:metabolism; D019830:Adenosine-5'-(N-ethylcarboxamide); D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D003342:Corpus Striatum / Q000378:metabolism; D006168:Guinea Pigs; D015394:Molecular Structure; D016548:Prosencephalon / Q000378:metabolism; D058914:Purinergic Antagonists; D051381:Rats; D013329:Structure-Activity Relationship; D014970:Xanthines / Q000737:chemistry* / Q000494:pharmacology
chemical_list: D058914:Purinergic Antagonists; D014970:Xanthines; D019830:Adenosine-5'-(N-ethylcarboxamide); C027513:N(6)-cyclohexyladenosine; D000241:Adenosine