title: Prelude activities in the synthesis of tissue-specific secretory protein products.
abstract: In studying the process of protein synthesis of a silk-producing organism we have found that several macromolecules must be synthesized in order for the process to occur. Through time course studies, we have found that small RNAs may play a paramount role in directing the finely orchestrated process. Alanine tRNA, U1 snRNA, and 5S RNA have been identified through Northern blotting as molecules timely and tissue-specific synthesized and upgraded as a prelude activity for the silk being produced.
authors.affiliation: Department of Biology, University of Puerto Rico, Río Piedras 00931.
authors.forename: E
authors.initials: E
authors.lastname: Luciano
authors.forename: G
authors.initials: G
authors.lastname: Arroyo
authors.forename: T
authors.initials: T
authors.lastname: Candelas
authors.forename: G C
authors.initials: GC
authors.lastname: Candelas
mesh_terms: D000818:Animals; D015152:Blotting, Northern; D004586:Electrophoresis; D005260:Female; D005349:Fibroins / Q000096:biosynthesis*; D012342:RNA, Small Nuclear / Q000302:isolation & purification; D013112:Spiders / Q000378:metabolism*
chemical_list: D012342:RNA, Small Nuclear; D005349:Fibroins