title: The fate of tumour rests following removal of acoustic neuromas: an MRI Gd-DTPA study.
abstract: The fate of capsular fragments left attached to vital structures at the time of otherwise total tumour removal was studied in 14 of 21 such patients who underwent acoustic neuroma surgery. Imaging using magnetic resonance Gd-DTPA at post-operative intervals of 6 months-12 years (mean 70 months) showed evidence of persistent tumour in half the patients. None of the patients had developed new symptoms and computed tomography had failed to demonstrate tumour recurrence. Persistence of the tumour was more likely if the residual fragments were not cauterized at the time of operation. Four of the seven persisting tumour rests showed evidence of gradual enlargement. The implications for patient management, particularly if an attempt is made to preserve hearing, are discussed.
authors.affiliation: Department of Otolaryngology, Manchester Royal Infirmary, UK.
authors.forename: R H
authors.initials: RH
authors.lastname: Lye
authors.forename: A
authors.initials: A
authors.lastname: Pace-Balzan
authors.forename: R T
authors.initials: RT
authors.lastname: Ramsden
authors.forename: J E
authors.initials: JE
authors.lastname: Gillespie
authors.forename: J M
authors.initials: JM
authors.lastname: Dutton
mesh_terms: D000328:Adult; D002531:Cerebellum / Q000473:pathology; D003287:Contrast Media; D005260:Female; D005500:Follow-Up Studies; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D009464:Neuroma, Acoustic / Q000473:pathology / Q000601:surgery*; D009942:Organometallic Compounds; D004369:Pentetic Acid; D011183:Postoperative Complications / Q000473:pathology*
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA