[Role of the HLA system in the functioning of the immune system].
HLA molecules share a particular architecture that allow them to present various peptides. They belong to 2 different subfamilies (class I and class II) working in parallel: each class restricts the presentation of potentially immunogenic peptides to a peculiar T cells subpopulation. This lead HLA system to be one of the possible components of the allergic background.
Renier
G
G
Laboratoire d'Immunologie, CHRU, Angers.
D000938:Antigen-Presenting Cells / Q000276:immunology; D000941:Antigens / Q000276:immunology / Q000378:metabolism; D006680:HLA Antigens / Q000145:classification / Q000235:genetics / Q000276:immunology* / Q000648:ultrastructure; D006801:Humans; D008285:Major Histocompatibility Complex; D008958:Models, Molecular; D010446:Peptide Fragments / Q000276:immunology / Q000378:metabolism; D011948:Receptors, Antigen, T-Cell / Q000276:immunology; D016176:T-Lymphocyte Subsets / Q000276:immunology
D000941:Antigens; D006680:HLA Antigens; D010446:Peptide Fragments; D011948:Receptors, Antigen, T-Cell
Le rôle du système HLA dans le fonctionnement du système immunitaire.