[The effects of captopril in stable angina pectoris].
Eighteen normotensive patients with coronary disease and stable effort-induced angina were selected. The effect of captopril was studied. A Bruce stress test was obtained before and after administration of conventional treatment with captopril or placebo. The captopril induced less systolic pressure elevation during maximal exercise without modification of heart rate. By decreasing myocardial oxygen consumption, increasing the time in which angina appears during exercise. Captopril may prove to be useful adjunct to the antianginal drug regimens of patients with stable angina and systolic arterial pressure greater than 110 mm Hg.
Rodríguez Gilabert
C
C
Servicio de Cardiología, Centro Médico Nacional Adolfo Ruiz Cortínes, IMSS, Veracruz.
Antúnez Sánchez
J
J
Miravete Oropeza
R
R
D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D001794:Blood Pressure / Q000187:drug effects; D002216:Captopril / Q000008:administration & dosage / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged
D002216:Captopril
Efectos del captopril en angina de pecho estable.