title: Hypertrophic gastropathy with transient sessile polyps.
abstract: We report an 8-year-old boy with hypertrophic gastropathy (HG) associated with duodenal Giardia lamblia infestation. The follow-up was complicated by the development of gastric polyps at the site of previous biopsies that spontaneously disappeared within 15 months. Despite the histological similarity, the different course between Ménétrier's disease (MD) in adults (chronic, with frequent development of sessile or pedunculate polyps) and HG (uncomplicated and usually spontaneously resolving) suggests a different pathogenesis. Viral (cytomegalovirus) and bacterial (Helicobacter pylori) infections have been described in association with HG and they could play an important pathogenetic role. The term HG better defines the childhood disease in which a conservative management is recommended.
authors.affiliation: 3rd Pediatric Department, G. Gaslini Institute, Genoa, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Pesce
authors.forename: A
authors.initials: A
authors.lastname: Barabino
authors.forename: C
authors.initials: C
authors.lastname: Dufour
authors.forename: P E
authors.initials: PE
authors.lastname: Caffarena
authors.forename: F
authors.initials: F
authors.lastname: Callea
authors.forename: R
authors.initials: R
authors.lastname: Gatti
mesh_terms: D000818:Animals; D002648:Child; D005753:Gastric Mucosa / Q000473:pathology; D016829:Giardia lamblia; D005873:Giardiasis / Q000150:complications; D006801:Humans; D006984:Hypertrophy / Q000150:complications / Q000175:diagnosis / Q000382:microbiology; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D011127:Polyps / Q000188:drug therapy / Q000209:etiology*; D011706:Pyloric Antrum / Q000473:pathology; D012709:Serum Albumin / Q000627:therapeutic use; D013272:Stomach Diseases / Q000473:pathology*
chemical_list: D012709:Serum Albumin; D008795:Metronidazole