title: Clinical profile and factors affecting mortality in acute renal failure.
abstract: The records of 110 patients with acute renal failure (ARF) admitted to the Department of Medicine of the Philippine General Hospital during a 5-year period (1983-1988) were reviewed. The objectives were to evaluate the clinical profile of ARF patients and to determine what factors influenced mortality. Infection significantly influenced the causation and prognosis of ARF. Fifteen patients died, for an overall mortality rate of 14%. Forty-six clinical variables were analyzed in order to identify factors correlated with mortality. Four variables significantly increased the risk of death from ARF: older age, hyperkalemia, oliguria, and presence of sepsis on admission. These characteristics define a subset of patients for whom more aggressive treatment of ARF is warranted.
authors.affiliation: Department of Medicine, Philippine General Hospital, University of the Philippines, College of Medicine, Manila.
authors.forename: C M
authors.initials: CM
authors.lastname: Dela Cruz
authors.forename: L
authors.initials: L
authors.lastname: Pineda
authors.forename: G
authors.initials: G
authors.lastname: Rogelio
authors.forename: F
authors.initials: F
authors.lastname: Alano
mesh_terms: D058186:Acute Kidney Injury / Q000097:blood / Q000401:mortality* / Q000652:urine; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001424:Bacterial Infections / Q000150:complications; D005260:Female; D006801:Humans; D006947:Hyperkalemia / Q000150:complications; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D009846:Oliguria / Q000150:complications; D012079:Renal Circulation / Q000502:physiology; D012189:Retrospective Studies; D012307:Risk Factors