Analysis of the protective effects of 21-aminosteroids in MPP(+)-induced neurotoxicity to dopaminergic neurons in mesencephalic cultures.
Sanchez-Ramos
J R
JR
Department of Neurology, University of Miami School of Medicine, Florida 33136.
Song
S
S
Oppenheimer
J
J
Mash
D
D
Weiner
W J
WJ
D015655:1-Methyl-4-phenylpyridinium / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002352:Carrier Proteins / Q000378:metabolism; D016923:Cell Death / Q000187:drug effects*; D002462:Cell Membrane / Q000378:metabolism; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D003342:Corpus Striatum / Q000378:metabolism; D004298:Dopamine / Q000378:metabolism*; D050483:Dopamine Plasma Membrane Transport Proteins; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D008454:Mazindol / Q000378:metabolism; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D008636:Mesencephalon / Q000166:cytology* / Q000378:metabolism; D009419:Nerve Tissue Proteins; D009474:Neurons / Q000166:cytology* / Q000187:drug effects / Q000378:metabolism; D009498:Neurotoxins / Q000494:pharmacology*; D013256:Steroids / Q000494:pharmacology*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
D000975:Antioxidants; D002352:Carrier Proteins; D050483:Dopamine Plasma Membrane Transport Proteins; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D009419:Nerve Tissue Proteins; D009498:Neurotoxins; D013256:Steroids; D005680:gamma-Aminobutyric Acid; D008454:Mazindol; D015655:1-Methyl-4-phenylpyridinium; D004298:Dopamine