Learning of rats under amnesia caused by pentobarbital.
Dissociated learning of rats in the normal state and the state of amnesia produced by pentobarbital (15 mg/kg, ip) was carried out. Rats were trained to approach a shelf where they received food reinforcement. In Group 1 the rats were trained under the influence of pentobarbital to run to the same shelf as in the normal state. In Group 2 the rats were trained to approach different shelves in different drug states. It was shown that memory dissociation occurred in both groups. Differences in the parameters of training under the influence of pentobarbital between Groups 1 and 2 were revealed. These findings show that the brain-dissociated state induced by pentobarbital is formed with the participation of the mechanisms of information perception.
Arkhipov
V I
VI
Institute of Biological Physics, Academy of Sciences USSR, Pushchino.
D000818:Animals; D001070:Appetitive Behavior / Q000187:drug effects*; D004193:Discrimination Learning / Q000187:drug effects*; D008297:Male; D011939:Mental Recall / Q000187:drug effects*; D009949:Orientation / Q000187:drug effects*; D010424:Pentobarbital / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D012153:Retention, Psychology / Q000187:drug effects*
D010424:Pentobarbital