[Lymphocyte subpopulations in inflammatory periapical lesions. A histopathological and immunohistochemical study in 10 cases].
The authors, thanks to the application of monoclonal antibodies, as well as the immunohistochemical technique of APAAP, have traced the qualitative and quantitative features of inflammatory cells implied in periapical lesions. Moreover ten patients, of whom 6 males and 4 females aged between 20 and 60 have been tested. The immunohistochemical reactions revealed a heterogeneous population of B and T (T4-T8) lymphocytes, together with myeloid trunk cells (granulocytes and histiocytes). The B lymphocytes form nearly 31.5% of all the inflammatory cell, whereas the T types form about 55.8. The granulo-histiocyte part implies 11.1% of all the inflammatory cells themselves. The average percentages of the roted inflammatory cells have been compared with two diagnostic categories of periapical granuloma and periapical cyst. However, by comparing the obtained results with the ones described by other authors, we notice agreement as for as qualitative analysis is concerned, while as for quantitative analysis, some differences are proved. Finally, this situation shows that the quantitative demonstration of inflammatory cell populations is only a moment in the development of immune reactions in the inflammatory tissue.
Riccio
C
C
Istituto di Clinica Odontoiatrica e Stomatologica, I Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli Federico II.
Scognamiglio
R
R
D000328:Adult; D005260:Female; D016591:Histocytological Preparation Techniques; D006801:Humans; D007124:Immunoenzyme Techniques; D007150:Immunohistochemistry; D016131:Lymphocyte Subsets / Q000378:metabolism / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010483:Periapical Diseases / Q000378:metabolism / Q000473:pathology; D010484:Periapical Granuloma / Q000378:metabolism / Q000473:pathology; D010485:Periapical Periodontitis / Q000378:metabolism / Q000473:pathology*; D011842:Radicular Cyst / Q000378:metabolism / Q000473:pathology
Sottopopolazioni linfocitarie nelle lesioni infiammatorie periapicali. Studio isotopatologico ed immunoistochimico su 10 casi.