[Labetalol in the prophylaxis of postoperative arterial hypertension in surgery of the posterior cranial fossa].
Increased catecholamines are one of the factors responsible for post-operative arterial hypertension. In order to prevent this severe complication labetalol, an alpha and beta blocking drug, was infused following the closure of the dura mater in half of the patients studied. For two hours after surgery blood pressure values in treated patients were constantly lower than those recorded in the control group, thus confirming the efficacy of this drug in preventing the cardiocirculatory effects of increased adrenalin and noradrenalin.
Montolivo
M
M
Istituto Nazionale Neurologico, C. Besta, Milano.
Gemma
M
M
Pastore
J C
JC
Regi
B
B
Bricchi
M
M
Vescovi
A
A
Fiacchino
F
F
D000293:Adolescent; D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000601:surgery*; D003388:Cranial Fossa, Posterior; D005260:Female; D006801:Humans; D006973:Hypertension / Q000517:prevention & control*; D007741:Labetalol / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*
D007741:Labetalol
Il labetalolo come profilassi della ipertensione arteriosa post-operatoria nella chirurgia della fossa cranica posteriore.