title: Effect of intensive endurance training on lipoprotein profiles in young and older men.
abstract: Although there are considerable data concerning the effects of endurance exercise training (ET) on plasma lipoproteins, the results have been quite inconsistent. The observed variability of response may be related to the age, sex, adiposity, or diet of the subjects tested, or to the type and intensity of the exercise intervention. Furthermore, there is relatively little such data in older individuals. Therefore, in the present study, we investigated the effects of intensive ET on lipoprotein profiles in healthy young (n = 12; 28.2 +/- 2.4 years) and older (n = 15; 67.5 +/- 5.8 years) men. Unlike subjects in most similar studies, our subjects were weight-stabilized on a constant-composition diet for 21 days prior to determination of the lipoprotein profile before and after the ET program. At baseline, the two groups were not significantly different with respect to any individual component of their lipoprotein profiles, relative weight, or percent body fat, but the older men had a more central distribution of fat by both waist to hip ratio (WHR) and computed tomography (CT). Maximal aerobic power, expressed per kilogram of body weight (VO2 max), was 33% lower (P less than .001) in the older men at baseline. Following the 6-month, walk/jog/bike ET program (5 d/wk), both the young (+18%, P less than .001) and the older (+22%, P less than .001) men increased their VO2 max. This was associated with small, but significant, decrements in weight, percent body fat, and WHR only in the older men.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Medicine, University of Washington, Seattle.
authors.forename: R S
authors.initials: RS
authors.lastname: Schwartz
authors.forename: K C
authors.initials: KC
authors.lastname: Cain
authors.forename: W P
authors.initials: WP
authors.lastname: Shuman
authors.forename: V
authors.initials: V
authors.lastname: Larson
authors.forename: J R
authors.initials: JR
authors.lastname: Stratton
authors.forename: J C
authors.initials: JC
authors.lastname: Beard
authors.forename: S E
authors.initials: SE
authors.lastname: Kahn
authors.forename: M D
authors.initials: MD
authors.lastname: Cerqueira
authors.forename: I B
authors.initials: IB
authors.lastname: Abrass
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001823:Body Composition; D002784:Cholesterol / Q000097:blood; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008875:Middle Aged; D010806:Physical Education and Training; D010807:Physical Endurance; D014280:Triglycerides / Q000097:blood
chemical_list: D008074:Lipoproteins; D014280:Triglycerides; D002784:Cholesterol