The effect of acetazolamide on essential tremor: an open-label trial.
We studied the effect of the carbonic anhydrase inhibitor acetazolamide on 24 patients with essential tremor by patient self-evaluation of functional disability, rating of motor task function, and clinical rating of tremor severity. Acetazolamide significantly reduced tremor severity, but there was no statistically significant change in patient self-assessment of function or motor task rating. Although side effects were common, over half the patients elected to remain on the drug.
Busenbark
K
K
Department of Neurology, University of Kansas Medical Center, Kansas City 66103.
Pahwa
R
R
Hubble
J
J
Koller
W
W
D000086:Acetazolamide / Q000009:adverse effects / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014202:Tremor / Q000188:drug therapy*
D000086:Acetazolamide