Genetic analysis of influenza virus.
The newly developed ribonucleoprotein reconstitution and transfection systems have facilitated the characterization of cis and trans functions required for transcription and replication of the influenza virus genome. For the first time, the genome of a negative-strand RNA virus can be manipulated using recombinant DNA techniques.
Luo
G
G
Department of Microbiology, Mount Sinai School of Medicine, New York, New York 10029-6574.
Palese
P
P
D001483:Base Sequence; D008969:Molecular Sequence Data; D009975:Orthomyxoviridae / Q000235:genetics*; D014158:Transcription, Genetic / Q000235:genetics; D014779:Virus Replication / Q000235:genetics*