title: Higher rate of evolution of X chromosome alpha-repeat DNA in human than in the great apes.
abstract: The rate of introduction of neutral mutations is lower in man than in other primates, including the chimpanzee. This species is generally regarded as our closest relative among the great apes. We present here an analysis of sequences of X chromosomal alphoid repetitive DNA from man and the great apes, which supports the closer relationship between man and chimpanzee and indicates a considerably increased rate of recombination in the human repeat DNA. These results indicate that the 'molecular clock' is running more quickly in man.
authors.affiliation: Institute of Medical Microbiology, University of Aarhus, Denmark.
authors.forename: H B
authors.initials: HB
authors.lastname: Laursen
authors.forename: A L
authors.initials: AL
authors.lastname: Jørgensen
authors.forename: C
authors.initials: C
authors.lastname: Jones
authors.forename: A L
authors.initials: AL
authors.lastname: Bak
mesh_terms: D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D015139:Blotting, Southern; D002460:Cell Line; D003001:Cloning, Molecular; D006224:Cricetinae; D004247:DNA; D005260:Female; D015186:Hominidae / Q000235:genetics*; D006801:Humans; D051379:Mice; D008969:Molecular Sequence Data; D010802:Phylogeny; D011323:Primates / Q000235:genetics; D012091:Repetitive Sequences, Nucleic Acid; D013045:Species Specificity; D014960:X Chromosome
chemical_list: D004247:DNA