title: [Changes in lipid metabolism in patients with arteriosclerosis obliterans after charcoal hemoperfusion and hypolipidemic therapy in the preoperative period].
abstract: The paper analyzes the results of the treatment of 26 patients with atherosclerosis obliterans of the lower extremities, which has been performed to make an intensive hypolipidemic preparation for an operation. The comprehensive approach based on the combination of medication (nicotinic acid, and its derivatives, cholestyramine, and SKH -2K charcoal hemoperfusion ) and efferent therapy reduced the plasma levels of total cholesterol by 27%, triglycerides to 48%, low density lipoprotein cholesterol to 40%, and increased high density lipoprotein cholesterol up to 72%. The similar course therapy may be repeatedly used in a follow-up of this group of patients.
authors.forename: S G
authors.initials: SG
authors.lastname: Burlakov
authors.forename: A A
authors.initials: AA
authors.lastname: Diuzhikov
authors.forename: V I
authors.initials: VI
authors.lastname: Beliavskiĭ
authors.forename: L A
authors.initials: LA
authors.lastname: Golenko
authors.forename: A A
authors.initials: AA
authors.lastname: Domnikova
mesh_terms: D000924:Anticholesteremic Agents; D001162:Arteriosclerosis Obliterans / Q000097:blood* / Q000601:surgery; D002606:Charcoal / Q000008:administration & dosage*; D002784:Cholesterol / Q000097:blood*; D006464:Hemoperfusion / Q000379:methods*; D006801:Humans; D000960:Hypolipidemic Agents; D007866:Leg / Q000098:blood supply*; D008875:Middle Aged; D011300:Preoperative Care; D014280:Triglycerides / Q000037:antagonists & inhibitors / Q000097:blood*; D014971:Xanthinol Niacinate / Q000008:administration & dosage*
chemical_list: D000924:Anticholesteremic Agents; D000960:Hypolipidemic Agents; C029814:SKN hemosorbents; D014280:Triglycerides; D002606:Charcoal; D014971:Xanthinol Niacinate; D002784:Cholesterol
vernacular_title: Izmeneniia lipidnogo obmena u bol'nykh obliteriruiushchim atero- sklerozom pod vliianiem gemokarboperfuzii i gipolipidemicheskoĭ terapii pri provedenii predoperatsionnoĭ podgotovki.