title: The SRF and MCM1 transcription factors.
abstract: The mammalian transcription factor SRF (serum-response factor) and the related Saccharomyces cerevisiae transcription factor MCM1 are the prototypes of a new class of dimeric DNA-binding proteins. Their function is regulated in part by the interactions of their DNA-binding domains with accessory proteins. Recent work has advanced the functional characterization of the contributions of SRF and MCM1, and their accessory proteins to transcriptional activation.
authors.affiliation: Imperial Cancer Research Fund, London, UK.
authors.forename: R
authors.initials: R
authors.lastname: Treisman
authors.forename: G
authors.initials: G
authors.lastname: Ammerer
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000502:physiology; D005656:Fungal Proteins / Q000737:chemistry; D026341:Minichromosome Maintenance 1 Protein; D008969:Molecular Sequence Data; D009687:Nuclear Proteins / Q000737:chemistry / Q000502:physiology; D026362:Serum Response Factor; D014157:Transcription Factors / Q000737:chemistry / Q000502:physiology
chemical_list: D004268:DNA-Binding Proteins; D005656:Fungal Proteins; D026341:Minichromosome Maintenance 1 Protein; D009687:Nuclear Proteins; D026362:Serum Response Factor; D014157:Transcription Factors