Iopamidol in cardioangiography: a retrospective, multicentre study. Part II. Paediatric patients.
To evaluate the complication rate in paediatric cardioangiography with the nonionic contrast medium iopamidol data on 8,166 procedures were retrospectively collected in 12 centres. The overall complication rate was 3.78% (309/8,166). 3.44% were related to the procedure, and 0.34% to the contrast medium. The mortality rate varied with age. It was higher in patients less than 2 months (0.38%) than in patients greater than 2 months-2 years (0.06%) and in patients older than 2 years (0.03%). The total complication rate was higher than the one observed in a similar retrospective analysis performed in adult patients (1.89%). This difference is probably due to higher risk conditions of the younger patients. However the contrast medium related complication rate (0.34% vs 0.4%) and the mortality rate (0.11% vs 0.1%) were comparable, confirming the good tolerability of iopamidol in cardiac catheterisation also in paediatric patients.
Ballerini
L
L
Dipartimento di Cardiologia Pediatrica, Ospedale Bambin Gesù Roma, Italy.
Barbaresi
F
F
Binaghi
G
G
Cernigliaro
C
C
Chioin
R
R
Fattori
R
R
Inglese
L
L
Invernizzi
G
G
Leto di Priolo
S
S
Onorato
E
E
D000367:Age Factors; D000790:Angiocardiography / Q000009:adverse effects / Q000379:methods* / Q000401:mortality / Q000706:statistics & numerical data; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000209:etiology / Q000401:mortality; D002648:Child; D004341:Drug Evaluation; D006801:Humans; D007479:Iopamidol / Q000008:administration & dosage / Q000009:adverse effects; D007558:Italy / Q000453:epidemiology; D012189:Retrospective Studies; D012737:Sex Factors
D007479:Iopamidol