title: Sleep electroencephalogram at the early stage of Creutzfeldt-Jakob disease.
abstract: We describe sleep EEG studies in three patients at the early stage of Creutzfeldt-Jakob disease. Little work has been devoted to the study of the sleep EEG in the course of the CJ disease: disorganized sleep architecture was noted, associated with a decrease in stage 4 and an almost complete disappearance of the REM stage. Our patients were considered to have normal stage 2; yet spindles and K complexes were rare at this stage. No evolution towards stage 4 was noted. The percentage of rapid eye movement sleep was significantly low in two cases and normal in one case. Sleep disturbances in the other dementing disorders are reported.
authors.affiliation: Service de Neurochirurgie, CHU Timone, Marseille, France.
authors.forename: A
authors.initials: A
authors.lastname: Donnet
authors.forename: G
authors.initials: G
authors.lastname: Farnarier
authors.forename: D
authors.initials: D
authors.lastname: Gambarelli
authors.forename: U
authors.initials: U
authors.lastname: Aguglia
authors.forename: H
authors.initials: H
authors.lastname: Regis
mesh_terms: D000368:Aged; D007562:Creutzfeldt-Jakob Syndrome / Q000503:physiopathology*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008875:Middle Aged; D012890:Sleep / Q000502:physiology*