title: Rapid determination of amino acids by high-performance liquid chromatography: release of amino acids by perfused rat liver.
abstract: Perfused rat liver can be considered as one of the most suitable ex vivo models for studies of liver metabolism. To assess the possible effect of L-carnitine and some of its acyl esters on proteolysis in the rat liver, the amino acid derivatization and high-performance liquid chromatographic separation of Tapuhi et al. [Anal. Biochem., 115 (1981) 123] was modified.
authors.affiliation: Department of Biochemistry, Research and Development, Sigma-tau SpA, Rome, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Zezza
authors.forename: J
authors.initials: J
authors.lastname: Kerner
authors.forename: M R
authors.initials: MR
authors.lastname: Pascale
authors.forename: R
authors.initials: R
authors.lastname: Giannini
authors.forename: E A
authors.initials: EA
authors.lastname: Martelli
mesh_terms: D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D002331:Carnitine / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D006868:Hydrolysis; D008099:Liver / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D000596:Amino Acids; D002331:Carnitine