title: The reaction of copper and other projectile metals in body tissues.
abstract: To determine the effect of copper in tissue, copper specimens, along with other metals commonly used in firearm projectiles, were implanted into rats. Copper consistently produced a necrotic, abscesslike reaction in all tissues tested. Nickel produced a similar reaction, although of lesser magnitude. Aluminum, zinc, and lead produced no significant tissue reaction.
authors.affiliation: Department of Surgery, Rhode Island Hospital, Providence.
authors.forename: R L
authors.initials: RL
authors.lastname: Wigle
mesh_terms: D000038:Abscess / Q000209:etiology / Q000503:physiopathology; D000818:Animals; D003300:Copper; D003964:Diaphragm / Q000187:drug effects / Q000503:physiopathology; D005549:Foreign-Body Reaction / Q000473:pathology / Q000503:physiopathology*; D007082:Ileum / Q000187:drug effects / Q000503:physiopathology; D008297:Male; D008670:Metals; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D008670:Metals; D003300:Copper