title: [Osteoporosis as the first manifestation of minor beta-thalassemia].
abstract: We present the case of a 48-year-old premenopausal woman with right lumbosciatalgia secondary to osteoporosic vertebral collapses. Two of her three offsprings, a 31-year-old man and a 16-year-old woman, had chronic dorsolumbalgia, the study of which suggested the diagnosis of minor beta-thalassemia. As opposed to thalassemic osteoarthropathy, frequently observed in the forms of "major" and "minor" beta-thalassemia, rheumatic manifestations have almost never been described in the "minor" forms. We highlight the possibility of symptomatic osteoporosis as the first manifestation and we review the locomotive disorders associated to this hemoglobinopathy.
authors.affiliation: Unidad de Reumatología, Hospital Juan Canalejo, La Coruña.
authors.forename: N
authors.initials: N
authors.lastname: Gómez Rodríguez
authors.forename: J M
authors.initials: JM
authors.lastname: Sánchez Bursón
authors.forename: A
authors.initials: A
authors.lastname: Atanes Sandoval
authors.forename: J
authors.initials: J
authors.lastname: Graña Gil
authors.forename: J
authors.initials: J
authors.lastname: de Toro Santos
authors.forename: F
authors.initials: F
authors.lastname: Galdo Fernández
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000209:etiology*; D013789:Thalassemia / Q000175:diagnosis* / Q000235:genetics
vernacular_title: Osteoporosis como primera manifestación de la beta-talasemia minor.