title: Oculocutaneous manifestations of the erythema multiforme/Stevens-Johnson syndrome/toxic epidermal necrolysis spectrum.
abstract: Although they were once believed to be distinct diseases, many observers currently consider erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis to represent a mild-to-severe continuum of the same process. Each shares certain clinical, histologic, and etiologic characteristics; among the latter two are frequent ocular involvement. Because long-term ophthalmic sequelae may be catastrophic, early recognition and therapy of this acute oculocutaneous disease spectrum are critically important.
authors.affiliation: Department of Ophthalmology, Oregon Health Sciences University, Portland.
authors.forename: J
authors.initials: J
authors.lastname: Wilkins
authors.forename: L
authors.initials: L
authors.lastname: Morrison
authors.forename: C R
authors.initials: CR
authors.lastname: White
mesh_terms: D003231:Conjunctivitis / Q000150:complications; D004774:Entropion / Q000150:complications; D004892:Erythema Multiforme / Q000150:complications* / Q000473:pathology; D005128:Eye Diseases / Q000150:complications* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007638:Keratoconjunctivitis Sicca / Q000150:complications; D008297:Male; D009077:Mucins / Q000172:deficiency; D013262:Stevens-Johnson Syndrome / Q000150:complications* / Q000473:pathology
chemical_list: D009077:Mucins