title: Comparison of technetium-99m-MIBI and thallium-201-chloride uptake in primary thyroid lymphoma.
abstract: A case of primary thyroid lymphoma demonstrating uptake of 99mTc-hexakis-2-methoxy isobutyl isonitrile (MIBI) is presented. The 99mTc-MIBI image more clearly delineated the extent of tumor as demonstrated on CT compared to 201Tl-chloride and [99mTc]pertechnetate images. Following two courses of chemotherapy, repeat radionuclide studies and CT scan showed complete resolution of the thyroid tumor. Technetium-99m-MIBI may be useful in the assessment of disease activity and monitoring response to treatment in patients with lymphoma.
authors.affiliation: Nuclear Medicine Service, Memorial Sloan-Kettering Cancer Center, New York, New York 10021.
authors.forename: A M
authors.initials: AM
authors.lastname: Scott
authors.forename: L
authors.initials: L
authors.lastname: Kostakoglu
authors.forename: J P
authors.initials: JP
authors.lastname: O'Brien
authors.forename: D J
authors.initials: DJ
authors.lastname: Straus
authors.forename: H M
authors.initials: HM
authors.lastname: Abdel-Dayem
authors.forename: S M
authors.initials: SM
authors.lastname: Larson
mesh_terms: D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000000981:diagnostic imaging* / Q000378:metabolism; D016403:Lymphoma, Large B-Cell, Diffuse / Q000000981:diagnostic imaging* / Q000378:metabolism; D008875:Middle Aged; D009570:Nitriles / Q000493:pharmacokinetics*; D015609:Organotechnetium Compounds / Q000493:pharmacokinetics*; D011877:Radionuclide Imaging; D017256:Technetium Tc 99m Sestamibi; D013794:Thallium Radioisotopes / Q000493:pharmacokinetics*; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism
chemical_list: D009570:Nitriles; D015609:Organotechnetium Compounds; D013794:Thallium Radioisotopes; D017256:Technetium Tc 99m Sestamibi