title: Reference values for renal concentrating capacity in children by the desmopressin test.
abstract: Reference values are reported for maximal renal concentrating capacity in children using intranasally administered desmopressin. The report is based on 591 tests in 473 healthy children aged 0.5-13 years. The concentrating capacity increased markedly during the first years of life and reached a plateau at the age of 3 years. The mean value minus two standard deviations was 525 mosmol/kg at 1 year of age and 825 mosmol/kg at 3 years of age.
authors.affiliation: Department of Paediatrics, University of Gothenburg, Ostra sjukhuset, Sweden.
authors.forename: S
authors.initials: S
authors.lastname: Mårild
authors.forename: U
authors.initials: U
authors.lastname: Jodal
authors.forename: G
authors.initials: G
authors.lastname: Jonasson
authors.forename: L
authors.initials: L
authors.lastname: Mangelus
authors.forename: A
authors.initials: A
authors.lastname: Odén
authors.forename: N G
authors.initials: NG
authors.lastname: Persson
mesh_terms: D000281:Administration, Intranasal; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003894:Deamino Arginine Vasopressin / Q000008:administration & dosage; D006801:Humans; D007223:Infant; D007671:Kidney Concentrating Ability; D008722:Methods; D012016:Reference Values; D013223:Statistics as Topic; D013548:Sweden
chemical_list: D003894:Deamino Arginine Vasopressin