title: Sweet's syndrome responding to cyclosporin.
abstract: We report a case of Sweet's syndrome which responded to treatment with cyclosporin 4 mg/kg/day. Cyclosporin is effective in the treatment of many dermatoses, and although the immunosuppressive effects of cyclosporin are mainly attributed to inhibition of T-lymphocyte proliferation, it has also been shown to affect the functions of both neutrophils and monocytes. Possible mechanisms of action of cyclosporin in Sweet's syndrome are discussed.
authors.affiliation: Department of Dermatology, Leicester Royal Infirmary, U.K.
authors.forename: J F
authors.initials: JF
authors.lastname: Bourke
authors.forename: J
authors.initials: J
authors.lastname: Berth-Jones
authors.forename: R A
authors.initials: RA
authors.lastname: Graham-Brown
mesh_terms: D000328:Adult; D001706:Biopsy; D016572:Cyclosporine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D012867:Skin / Q000473:pathology; D016463:Sweet Syndrome / Q000188:drug therapy* / Q000473:pathology
chemical_list: D016572:Cyclosporine