title: Insulin antagonizes the phagocytosis stimulating action of histamine in Tetrahymena.
abstract: Histamine increased specifically the phagocytic activity of the unicellular Tetrahymena, whereas insulin had no influence on it. Insulin antagonized the phagocytosis stimulating action of histamine after simultaneous exposure and after preexposure two days earlier as well, although in the latter case to a lesser degree. Double exposure to a combination of histamine+insulin didn't influence the phagocytic activity at all, demonstrating the histamine antagonizing effect of insulin in this model.
authors.affiliation: Department of Biology, Semmelweis University of Medicine, Budapest, Hungary.
authors.forename: G
authors.initials: G
authors.lastname: Csaba
authors.forename: Z
authors.initials: Z
authors.lastname: Darvas
mesh_terms: D000818:Animals; D006632:Histamine / Q000494:pharmacology*; D006633:Histamine Antagonists; D007328:Insulin / Q000494:pharmacology*; D010587:Phagocytosis / Q000187:drug effects*; D013769:Tetrahymena pyriformis / Q000187:drug effects* / Q000502:physiology
chemical_list: D006633:Histamine Antagonists; D007328:Insulin; D006632:Histamine