title: Treatment of calculi of the common bile duct.
abstract: Endoscopic sphincterotomy (EST) is regarded as an alternative therapeutic approach to the surgical treatment of choledocholithiasis. To clarify the indication for each of these two methods, a prospective study has been performed comparing patients with calculi of the common bile duct who had undergone endoscopic or surgical treatment. Mortality, morbidity and stone clearance were used as criteria for the evaluation of the dependence of age on results achieved by the two modalities. Of 306 patients with choledocholithiasis, 199 underwent surgical exploration of the duct and 107 underwent endoscopic sphincterotomy. Patients who were more than 60 years of age and had previously undergone cholecystectomy underwent endoscopic sphincterotomy. All other patients had surgical treatment. There were no significant differences among the two groups with regard to mortality rates. The incidence of relevant complications as well as the incidence of surgical revisions related to postoperative complications in the operation group was, however, significantly higher (p less than 0.05). In contrast with this, the incidence of retained stones was significantly lower (p less than 0.01) in the group that underwent surgical treatment (2.5 percent) than in the group that had endoscopy (11.2 percent). When assessing the results in terms of stone clearance, complications and mortality rates, findings seem to indicate that a safe limit for the application of surgical treatment would be 60 years of age, whereas older patients should be primarily considered as candidates for EST.
authors.affiliation: Department of Surgery II, University Hospital of Innsbruck, Austria.
authors.forename: G
authors.initials: G
authors.lastname: Schwab
authors.forename: R
authors.initials: R
authors.lastname: Pointner
authors.forename: G
authors.initials: G
authors.lastname: Wetscher
authors.forename: K
authors.initials: K
authors.lastname: Glaser
authors.forename: E
authors.initials: E
authors.lastname: Foltin
authors.forename: E
authors.initials: E
authors.lastname: Bodner
mesh_terms: D000367:Age Factors; D000368:Aged; D002763:Cholecystectomy; D005260:Female; D042882:Gallstones / Q000401:mortality / Q000601:surgery*; D006801:Humans; D015994:Incidence; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology; D011446:Prospective Studies; D012044:Regression Analysis; D012307:Risk Factors; D016717:Sphincterotomy, Endoscopic; D015996:Survival Rate