title: Intraoperative patient-controlled analgesia: an alternative to physician administration during outpatient monitored anesthesia care.
abstract: Outpatients undergoing minor diagnostic and therapeutic procedures associated with intermittent discomfort are frequently given bolus injections of intravenous opioid analgesics. In a group of 80 healthy women undergoing vaginal ovum pickup procedures, we evaluated patient-controlled administration of alfentanil using a patient-controlled analgesia device (with a lockout interval of 3 min) as an alternative to conventional physician-controlled administration. The two alfentanil administration techniques were equally effective in providing intraoperative analgesia. The average alfentanil dosage requirements were 1.49 +/- 0.50 and 1.46 +/- 0.55 micrograms.kg-1.min-1 (mean +/- SD) in the physician- and patient-controlled groups, respectively. The incidence of postoperative nausea was the same in both treatment groups (8%). Even with the mandatory lockout interval, intraoperative patient-controlled administration of alfentanil was comparable to physician-controlled administration with respect to patient comfort and satisfaction during vaginal ovum pickup procedures.
authors.affiliation: Department of Anesthesia, Royal Women's Hospital, Melbourne, Australia.
authors.forename: J
authors.initials: J
authors.lastname: Zelcer
authors.forename: P F
authors.initials: PF
authors.lastname: White
authors.forename: S
authors.initials: S
authors.lastname: Chester
authors.forename: J D
authors.initials: JD
authors.lastname: Paull
authors.forename: R
authors.initials: R
authors.lastname: Molnar
mesh_terms: D000328:Adult; D015760:Alfentanil / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D016058:Analgesia, Patient-Controlled; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D010146:Pain / Q000503:physiopathology; D010147:Pain Measurement; D012099:Reproductive Techniques; D014621:Vagina
chemical_list: D015760:Alfentanil