Colonization of Escherichia coli in young turkeys and chickens.
In order to investigate the possibility of pathogenic Escherichia coli penetrating the bloodstream via the intestinal mucosa in normal and stressed turkeys and chickens, birds were inoculated orally with the bacteria or exposed environmentally to it. Immediately after hatch, intestines contained a substantial number of coliform bacteria that increased with time. In orally infected turkeys, the pathogenic bacteria (nalidixic-acid-resistant O78) replaced 10%-50% of the native coliform flora but could not be isolated from the trachea or blood. Environmentally exposed groups exhibited pathogenic bacteria in intestines but not in blood. Stressing of exposed turkeys resulted in isolation of the pathogenic bacteria from blood and even spleen. In orally infected broiler chickens, stress resulted in bacteremia and mortality. Chickens that were exposed to pathogenic bacteria at a young age and showed no mortality or morbidity demonstrated no detrimental effects due to challenge with the same pathogenic bacteria later in life. Stress seems to cause penetration of the pathogenic bacteria into the bloodstream, which in turn can cause severe disease and mortality.
Leitner
G
G
Department of Animal Science, Hebrew University of Jerusalem, Faculty of Agriculture, Rehovot, Israel.
Heller
E D
ED
D000818:Animals; D016470:Bacteremia / Q000209:etiology / Q000382:microbiology / Q000662:veterinary; D002353:Carrier State / Q000382:microbiology / Q000662:veterinary; D002645:Chickens; D004926:Escherichia coli / Q000302:isolation & purification / Q000472:pathogenicity / Q000502:physiology*; D004927:Escherichia coli Infections / Q000209:etiology / Q000382:microbiology / Q000662:veterinary*; D005508:Food Deprivation; D006358:Hot Temperature / Q000009:adverse effects; D007422:Intestines / Q000382:microbiology; D011201:Poultry Diseases / Q000209:etiology / Q000382:microbiology*; D013154:Spleen / Q000382:microbiology; D013312:Stress, Physiological / Q000150:complications / Q000662:veterinary; D014422:Turkeys; D014868:Water Deprivation