[Familial occlusion of central veins associated with type II familial hyperlipoproteinemia].
We report, for the first time to the best of our knowledge, about a family in which 3 members (two of which were under 40 years of age) of two successive generations presented central retinal vein occlusions in relation to a type II hyperlipoproteinaemia. On the basis of the reported cases, it can be postulated that hyperlipoproteinaemia seems to be a serious potential risk factor for central retinal vein occlusion. The particular aspects of central vein occlusion in relation to hyperlipoproteinaemia are the elevated frequency of recurrences, the poor visual prognosis secondary to severity of veinous obstruction, and the increased incidence of these occlusions in younger patients. The discovery of a hyperlipoproteinaemia in young patients with central retinal vein occlusion should therefore incite prompt examination of other family members in order to initiate prophylactic hypolipaemic treatment.
Castella
A
A
Service d'ophtalmologie, Hôpital Jules Gonin, Université de Lausanne.
Othenin-Girard
P
P
D000368:Aged; D002784:Cholesterol / Q000097:blood; D005260:Female; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000097:blood / Q000235:genetics*; D008269:Macular Edema / Q000097:blood / Q000235:genetics; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D012170:Retinal Vein Occlusion / Q000097:blood / Q000235:genetics*; D014280:Triglycerides / Q000097:blood
D014280:Triglycerides; D002784:Cholesterol
Occlusions veineuses centrales familiales associées à une hyperlipoprotéinémie familiale de type II.