title: Expression of GAD mRNA in GABA interneurons of the rat medial frontal cortex.
abstract: The distribution of glutamic acid decarboxylase (GAD) mRNA containing cells was studied in the rat medial frontal cortex (MFC). The neurons labelled by the 35S-labelled cDNA probe were distributed uniformly throughout all the layers and represented 16% of the total neuronal population. It was possible to distinguish two cell populations expressing high and low levels of GAD mRNA corresponding to 63% and 27% of labelled cells, respectively. Concerning the laminar distribution of these two populations of GAD mRNA containing neurons, no marked difference was observed between the various areas of the MFC.
authors.affiliation: Laboratoire de Neurochimie-Anatomie, Université Paris 6-Pierre et Marie Curie, France.
authors.forename: S
authors.initials: S
authors.lastname: Rétaux
authors.forename: J F
authors.initials: JF
authors.lastname: Julien
authors.forename: M J
authors.initials: MJ
authors.lastname: Besson
authors.forename: J
authors.initials: J
authors.lastname: Penit-Soria
mesh_terms: D000818:Animals; D002452:Cell Count; D004790:Enzyme Induction; D005625:Frontal Lobe / Q000166:cytology* / Q000378:metabolism; D005968:Glutamate Decarboxylase / Q000032:analysis*; D007395:Interneurons / Q000201:enzymology*; D008297:Male; D012333:RNA, Messenger / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains; D005680:gamma-Aminobutyric Acid / Q000096:biosynthesis*
chemical_list: D012333:RNA, Messenger; D005680:gamma-Aminobutyric Acid; D005968:Glutamate Decarboxylase