Structure determination of a novel cyclic phosphocompound isolated from Desulfovibrio desulfuricans.
The structure of a novel diphosphodiester compound recently detected in Desulfovibrio desulfuricans cells [Santos, Fareleira, Pedregal, LeGall & Xavier (1991) Eur. J. Biochem. 201, 283-287] was fully elucidated using a combination of n.m.r. techniques in aqueous and in methanolic solutions. The novel metabolite was identified as 3-methyl-1,2,3,4-tetrahydroxybutane-1,3-cyclic bisphosphate, and the minimum energy conformation is presented. The two chiral centres have the relative configuration RS.
Turner
D L
DL
Department of Chemistry, University of Southampton, U.K.
Santos
H
H
Fareleira
P
P
Pacheco
I
I
LeGall
J
J
Xavier
A V
AV
D000440:Butanols / Q000737:chemistry* / Q000302:isolation & purification; D003901:Desulfovibrio / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D009943:Organophosphorus Compounds / Q000737:chemistry* / Q000302:isolation & purification; D013237:Stereoisomerism
D000440:Butanols; D009943:Organophosphorus Compounds; C075747:3-methyl-1,2,3,4-tetrahydroxybutane-1,3-cyclic bisphosphate