title: Umbilical artery and uteroplacental velocimetry in pregnancies complicated by idiopathic low birthweight centile.
abstract: Umbilical artery and uteroplacental Doppler flow velocity waveforms were studied in 35 pregnancies complicated by idiopathic low birthweight centile. Thirty fetuses (86%) were below the 5th centile birthweight for gestation. Fifteen (43%) had an abnormal umbilical artery systolic to diastolic ratio. Uteroplacental waveforms were recorded in 29 of the 35 pregnancies and five (17%) showed an abnormal systolic to diastolic ratio. Abnormal uteroplacental systolic to diastolic ratios were associated with a significantly earlier gestational age at delivery and significantly more cesarean sections for fetal distress compared with normal uteroplacental systolic to diastolic ratios (p less than or equal to 0.01). The absence of umbilical artery end-diastolic frequencies was associated with a significantly earlier gestational age at delivery compared with the presence of umbilical artery end-diastolic frequencies (p less than 0.005). No differences in pregnancy outcome were observed comparing normal with abnormal amniotic fluid volume assessment. These findings suggest that Doppler studies may be useful in estimating the risk of adverse perinatal outcome for small for gestational age fetuses with no identifiable cause.
authors.affiliation: Perinatal Research Center, Glasgow Royal Maternity Hospital, Scotland, United Kingdom.
authors.forename: F M
authors.initials: FM
authors.lastname: Fairlie
authors.forename: M
authors.initials: M
authors.lastname: Moretti
authors.forename: J J
authors.initials: JJ
authors.lastname: Walker
authors.forename: B M
authors.initials: BM
authors.lastname: Sibai
mesh_terms: D001783:Blood Flow Velocity; D003971:Diastole; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age / Q000502:physiology*; D010920:Placenta / Q000098:blood supply*; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology; D012307:Risk Factors; D013599:Systole; D014469:Umbilical Arteries / Q000502:physiology*; D014599:Uterus / Q000098:blood supply*