title: Chondrosarcoma: MR imaging with pathologic correlation.
abstract: Magnetic resonance (MR) images of 21 surgically confirmed chondrosarcomas were retrospectively reviewed in conjunction with plain radiographs and computed tomographic scans and correlated with pathologic findings. The tumors appeared lobulated, and signal intensity, as analyzed visually (intermediate on T1-weighted, high on T2-weighted images), was similar for all lesions, regardless of pathologic type. Size of lesion was not an indicator of grade. The appearances of mesenchymal and dedifferentiated chondrosarcomas mimicked that of conventional chondrosarcoma. Extraskeletal chondrosarcoma was visualized as a lobulated soft-tissue mass. In all cases, MR imaging accurately depicted intraosseous and soft-tissue extent of tumor noted at surgery and pathologic examination. Histologic type or grade of chondrosarcoma generally cannot be characterized on the basis of visual analysis of signal intensity noted on routine MR images. However, MR imaging is excellent for exact delineation of tumor extent.
authors.affiliation: Department of Diagnostic Radiology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
authors.forename: D G
authors.initials: DG
authors.lastname: Varma
authors.forename: A G
authors.initials: AG
authors.lastname: Ayala
authors.forename: C H
authors.initials: CH
authors.lastname: Carrasco
authors.forename: S Q
authors.initials: SQ
authors.lastname: Guo
authors.forename: R
authors.initials: R
authors.lastname: Kumar
authors.forename: J
authors.initials: J
authors.lastname: Edeiken
mesh_terms: D001859:Bone Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D001842:Bone and Bones / Q000473:pathology; D002813:Chondrosarcoma / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed