title: [Systemic corticosteroid therapy in non-arteritic anterior ischemic optic neuropathy].
abstract: A non-arteritic anterior ischemic optic neuropathy has usually a poor prognosis. Spontaneous remissions are extremely rare. In contrast to arteritic anterior ischemic neuropathy, systemic corticosteroids are generally accepted to be ineffective. Two cases of bilateral severe non-arteritic anterior ischemic optic neuropathy are reported who underwent full remission of their visual function directly related to high-dose systemic corticosteroids. It is hypothesized that, in acute phases of non-arteritic anterior ischemic optic neuropathy a significant reduction of tissue swelling and consecutive prelaminar reperfusion can be achieved with high-dose corticosteroids.
authors.affiliation: Universitäts-Augenklinik Bern.
authors.forename: J
authors.initials: J
authors.lastname: Menzi
authors.forename: F
authors.initials: F
authors.lastname: Körner
mesh_terms: D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D002537:Intracranial Arteriosclerosis / Q000150:complications / Q000188:drug therapy; D007511:Ischemia / Q000188:drug therapy*; D008875:Middle Aged; D009900:Optic Nerve / Q000098:blood supply*; D009902:Optic Neuritis / Q000188:drug therapy*; D011241:Prednisone / Q000008:administration & dosage*; D014792:Visual Acuity / Q000187:drug effects; D014794:Visual Fields / Q000187:drug effects
chemical_list: D011241:Prednisone
vernacular_title: Systemische Kortikosteroidtherapie bei nicht-arteriitischer anteriorer ischämischer Optikusneuropathie.