[Erythroleukemia in pregnancy with successful outcome of delivery].
A 37-year-old woman was admitted to our hospital because of anemia in the 33rd week of pregnancy. On admission, the hemoglobin was 7.6 g/dl, platelets 508,000/microliters and WBC 8,300/microliters with 4% blast cells. Bone marrow aspirate demonstrated 50% erythroblasts of nucleated cells, which had prominent megaloid and polynucleic changes, and 20% myeloblast cells. We diagnosed her as having erythroleukemia. Receiving packed-red-cell transfusions, she had a cesarean section, and gave birth to a female infant (BW 2,175 g) in the 34th week of pregnancy. At the same time, she had a total hysterectomy with left adnexectomy. The postoperative course was favorable. She had a combination chemotherapy of BHAC-DMP, resulting in a partial remission. After the second induction chemotherapy with subcutaneous use of G-CSF and BHAC-DMP, complete remission was obtained, which lasted for almost 17 months. The child is growing well without any hematological disorder.
Tomizuka
H
H
Department of Internal Medicine, Kamitsuga General Hospital.
Yatabe
M
M
Okudera
K
K
Hatake
K
K
Miwa
T
T
Sakamoto
S
S
Miura
Y
Y
Eguti
M
M
D000328:Adult; D002585:Cesarean Section; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D004915:Leukemia, Erythroblastic, Acute / Q000628:therapy; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000628:therapy; D011252:Pregnancy Complications, Neoplastic / Q000628:therapy; D011256:Pregnancy Outcome; D012074:Remission Induction