title: Gene therapy: a status report.
abstract: Gene therapy is a way to treat disease by transfer of genetic material into the cells of a diseased organism. Generally it is transferred in the form of one or few genes. There is a tremendous potential for application of this technique to the treatment of human hereditary diseases, particularly single gene disorders. Due to ethical and practical reasons, it is currently being used only as somatic cell therapy but it could be achieved by germline also. The major problem in gene therapy is achieving an efficient gene transfer and a persistent gene expression in appropriate somatic cells.
authors.affiliation: Department of Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow.
authors.forename: S
authors.initials: S
authors.lastname: Agarwal
authors.forename: R
authors.initials: R
authors.lastname: Khardori
authors.forename: N
authors.initials: N
authors.lastname: Khardori
mesh_terms: D000818:Animals; D003001:Cloning, Molecular; D004992:Ethics, Medical; D030342:Genetic Diseases, Inborn / Q000628:therapy; D005818:Genetic Engineering; D015316:Genetic Therapy; D006801:Humans; D051379:Mice; D011401:Promoter Regions, Genetic; D012106:Research; D014162:Transfection