Breast carcinoma and skeletal formation.
We have studied skeletal structure in 67 women with breast carcinoma and in 59 women without breast carcinoma, looking for differences of development that might be correlated with hormonal, metabolic or genetic abnormalities. We have measured the lengths of the limbs and of their segments (upper arm, forearm, thigh, leg), of the bisacromial and bitrochanteric transverse diameters and total height and height divided into the parts from vertex to pubis and from pubis to the ground. The analysis showed statistically significant coefficients of regression with presence of mammary carcinoma for height (0.0904262, S.D. 0.0461), length of thigh (0.12989, S.D. 0.03981) and length of lower leg (-0.68475, S.D. 0.1390). This skeletal type might be the expression of a genetic condition that is associated with the existence of mechanisms that permit development of mammary cancer.
Mondina
R
R
Consiglio Nazionale delle Ricerche, Clinica Ostetrica Ginecologica della Università, Milano, Italy.
Borsellino
G
G
Poma
S
S
Baroni
M
M
Di Nubila
B
B
Sacchi
P
P
D000328:Adult; D000368:Aged; D000886:Anthropometry; D001132:Arm / Q000473:pathology; D001827:Body Height; D001846:Bone Development; D001842:Bone and Bones / Q000473:pathology*; D001943:Breast Neoplasms / Q000209:etiology*; D002277:Carcinoma / Q000209:etiology*; D005260:Female; D006801:Humans; D007866:Leg / Q000473:pathology; D008875:Middle Aged