title: Biochemical studies on 2-deoxy-scyllo-inosose, an early intermediate in the biosynthesis of 2-deoxystreptamine. I. Chemical synthesis of 2-deoxy-scyllo-inosose and [2,2-2H2]-2-deoxy-scyllo-inosose.
abstract: A practical preparative method for 2-deoxy-scyllo-inosose, the earliest key intermediate leading to 2-deoxystreptamine, was devised as a prerequisite to more detailed biochemical studies on the biosynthesis of 2-deoxystreptamine. [2,2-2H2]-2-Deoxy-scyllo-inosose was also synthesized through a modified Ferrier reaction.
authors.affiliation: Department of Chemistry, Tokyo Institute of Technology, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Yamauchi
authors.forename: K
authors.initials: K
authors.lastname: Kakinuma
mesh_terms: D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D006595:Hexosamines / Q000096:biosynthesis; D007294:Inositol / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D006595:Hexosamines; D007294:Inositol; C075548:2-deoxyinosose; C007265:2-deoxystreptamine