title: A new approach to encapsulating non-steroidal anti-inflammatory drugs. V. Biopharmaceutical study of microcapsules of azapropazone coated with pectin and rutin.
abstract: Azapropazone was encapsulated with pectin-rutin mixture using the fluidized bed technique. The encapsulated particles showed higher dissolution rate and bioavailability but lower ulcerogenic activity as compared with the drug alone.
authors.affiliation: Faculty of Pharmacy, Mansoura University.
authors.forename: M M
authors.initials: MM
authors.lastname: Meshali
authors.forename: E Z
authors.initials: EZ
authors.lastname: el-Dien
authors.forename: S A
authors.initials: SA
authors.lastname: Omar
authors.forename: L A
authors.initials: LA
authors.lastname: Luzzi
mesh_terms: D000818:Animals; D001032:Apazone / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000633:toxicity; D001682:Biological Availability; D004339:Drug Compounding / Q000379:methods*; D008297:Male; D010316:Particle Size; D010368:Pectins / Q000737:chemistry*; D051381:Rats; D012431:Rutin / Q000737:chemistry*; D013276:Stomach Ulcer / Q000139:chemically induced
chemical_list: D012431:Rutin; D010368:Pectins; D001032:Apazone