title: Evaluation of serum ferritin as a marker for adult Still's disease activity.
abstract: Extremely high serum ferritin values (greater than 10,000 micrograms/l) were detected in two patients with adult Still's disease. The ferritin concentrations decreased to normal after adequate treatment. During a one year follow up ferritin concentration was helpful in monitoring disease activity and guiding decisions about treatment. Raised concentrations of soluble interleukin 2 receptors (sCD25) were also found. Detection of ferritin values above 3000 micrograms/l should lead to the consideration of Still's disease when there is an acute febrile illness without evidence for bacterial or viral infections, serum ferritin being suitable for monitoring treatment.
authors.affiliation: Department of Internal Medicine, Med Poliklink V, University of Heidelberg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Schwarz-Eywill
authors.forename: B
authors.initials: B
authors.lastname: Heilig
authors.forename: H
authors.initials: H
authors.lastname: Bauer
authors.forename: A
authors.initials: A
authors.lastname: Breitbart
authors.forename: A
authors.initials: A
authors.lastname: Pezzutto
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D005260:Female; D005293:Ferritins / Q000097:blood*; D006801:Humans; D008297:Male; D016706:Still's Disease, Adult-Onset / Q000097:blood* / Q000175:diagnosis
chemical_list: D015415:Biomarkers; D005293:Ferritins