Trimethoprim-resistant Escherichia coli in households of children attending day care centers.
Children in day care centers are frequently colonized with trimethoprim-resistant Escherichia coli. The frequency of transmission to family members was studied. Colonization with trimethoprim-resistant E. coli was detected in 13 (57%) of 23 day care center children. Among the 50 (98%) of 51 household members tested, colonization was detected in 13 (26%), representing 12 (52%) of 23 households tested. Households of colonized center children had significantly more colonized members than did households of noncolonized children (odds ratio, 13.3; 95% confidence interval, 1.3-172.6; P = .01). There was a trend toward higher prevalence of colonization in mothers (35%) and siblings (30%) than in fathers (12%). The same plasmid profiles of trimethoprim-resistant E. coli from center children were found among 8 (67%) of 12 colonized households. There was no association between antibiotic use and fecal colonization with trimethoprim-resistant E. coli. Thus, transmission of trimethoprim-resistant E. coli among children within day care centers and from center children to household members is common.
Fornasini
M
M
Department of Pediatrics, University of Texas Medical School, Houston.
Reves
R R
RR
Murray
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BE
Morrow
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Pickering
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LK
D002353:Carrier State / Q000453:epidemiology / Q000382:microbiology*; D002656:Child Day Care Centers; D002675:Child, Preschool; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000382:microbiology* / Q000635:transmission; D005190:Family; D005243:Feces / Q000382:microbiology; D006801:Humans; D007223:Infant; D010957:Plasmids; D015995:Prevalence; D014296:Trimethoprim Resistance