title: Management of persons exposed to multidrug-resistant tuberculosis.
abstract: Recent outbreaks of multidrug-resistant tuberculosis (MDR-TB) have posed challenges for the management of exposed persons. This report offers suggestions for evaluating and managing persons (i.e., contacts) who have been exposed to patients with infectious MDR-TB (TB due to strains of Mycobacterium tuberculosis resistant to both isoniazid [INH] and rifampin [RIF]), provides background information on alternative preventive therapy regimens with drugs other than INH or RIF, and presents considerations relevant to making a decision to offer one of these alternative regimens.
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use*; D002985:Clinical Protocols; D004196:Disease Outbreaks / Q000517:prevention & control; D004352:Drug Resistance, Microbial; D004359:Drug Therapy, Combination; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000187:drug effects*; D014376:Tuberculosis / Q000188:drug therapy / Q000517:prevention & control* / Q000635:transmission
chemical_list: D000995:Antitubercular Agents