title: Coeliac disease "anatomic pathology".
abstract: The microscopic diagnosis of coeliac disease is discussed. The small intestinal mucosal lesions observed in coeliac disease consist of a combination of epithelial alterations and inflammatory lesions starting with pre-infiltrative changes. In the early (?) changes an increase of lymphocytes is noted. The interactions probably finally lead to destruction or atrophy of the villi.
authors.affiliation: Department of Medical Research, University Hospital, Leuven, België.
authors.forename: K
authors.initials: K
authors.lastname: Geboes
authors.forename: N
authors.initials: N
authors.lastname: Ectors
authors.forename: V J
authors.initials: VJ
authors.lastname: Desmet
mesh_terms: D001706:Biopsy / Q000379:methods; D002446:Celiac Disease / Q000473:pathology*; D016099:Endoscopy, Gastrointestinal; D006684:HLA-DR Antigens / Q000302:isolation & purification; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology* / Q000648:ultrastructure
chemical_list: D006684:HLA-DR Antigens