[Differences in cataractogenesis according to neodymium-YAG laser injury site].
The author examined morphological changes of the lens induced by mechanical damage with a Q-switch Nd-YAG laser (anterior capsule, anterior subcapsular deep cortex, posterior capsule). In the ruptured anterior capsule group, epithelial cell proliferation covered the ruptured capsule, and separation of posterior subcapsular sutures and swelling of the posterior subcapsular end of lens fiber cells were observed. In the ruptured subcapsular deep cortex group, swollen lens fiber cells were observed in both the anterior subcapsular and the posterior subcapsular cortex. In the ruptured posterior capsule group, the ruptured cortex was not repaired. Swollen lens fiber cells were first recognized in areas surrounding the ruptured capsule, then at the posterior side of the equator, and finally at the anterior subcapsular cortex. The continuity of the lens capsule and lens fiber cells themselves is very important part to maintain lens clarity. The destruction of this feature induced swelling of fiber cells on the opposite side of the injury area.
Terubayashi
H
H
Department of Opthalmology, Kyoto Prefectural University of Medicine, Japan.
Okamoto
S
S
Ikebe
H
H
Akagi
Y
Y
D000818:Animals; D002386:Cataract / Q000209:etiology* / Q000473:pathology; D004195:Disease Models, Animal; D007834:Lasers / Q000009:adverse effects*; D007908:Lens, Crystalline / Q000293:injuries*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains