title: A case of diffuse lupus encephalopathy successfully treated with high-dose intravenous methylprednisolone.
abstract: We report a case of systemic lupus erythematosus (SLE) in a young woman who presented a serious encephalopathy with respiratory distress and coma, after arbitrary interruption of oral corticosteroid therapy when her first pregnancy ended in abortion. The patient showed rapid improvement on methylprednisolone pulse therapy. The case suggests the utility of such a therapy in severe, non focal, CNS complications of SLE.
authors.affiliation: Istituto di Scienze Neurologiche, I Facoltà di Medicina e Chirurgia, Università di Napoli.
authors.forename: G
authors.initials: G
authors.lastname: Di Iorio
authors.forename: U
authors.initials: U
authors.lastname: Picillo
authors.forename: P
authors.initials: P
authors.lastname: Santanelli
authors.forename: S
authors.initials: S
authors.lastname: Migliaresi
authors.forename: V
authors.initials: V
authors.lastname: Bonavita
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy; D008775:Methylprednisolone / Q000008:administration & dosage*
chemical_list: D008775:Methylprednisolone