title: Cadmium resistance in Gammarus pulex (L.).
abstract: The ability of Gammarus pulex to develop cadmium resistance through physiological acclimation was investigated. Organisms were found to be significantly more tolerant to acute cadmium toxicity after pre-exposure to sublethal concentrations of cadmium and zinc. The induced elevation in cadmium tolerance was shown to be associated with an increase in the body concentration of a metallothionein-like protein. Pre-exposure had no apparent effect on cadmium uptake, although it did influence the distribution of cadmium within the organisms. Whereas pre-exposure to low levels of zinc and cadmium increased cadmium tolerances in acute tests, it had no observable effects on sublethal responses measured during chronic exposure.
authors.affiliation: Department of Animal and Plant Sciences, University of Sheffield, United Kingdom.
authors.forename: A
authors.initials: A
authors.lastname: Stuhlbacher
authors.forename: L
authors.initials: L
authors.lastname: Maltby
mesh_terms: D000818:Animals; D001822:Body Burden; D002104:Cadmium / Q000633:toxicity*; D003445:Crustacea; D004351:Drug Resistance; D008297:Male; D008668:Metallothionein / Q000096:biosynthesis; D015032:Zinc / Q000494:pharmacology
chemical_list: C004203:cadmium-binding protein; D002104:Cadmium; D008668:Metallothionein; D015032:Zinc