title: Lung scintigraphy with [123I]IMP in patients with pulmonary tuberculosis.
abstract: Lung scintigraphy using N-isopropyl-p-[123I]iodoamphetamine (IMP) was performed on 26 patients with pulmonary tuberculosis. Early (5 min after injection) and late images (4 h after injection) were obtained with a large-field gamma-camera equipped with a digital computer. Lung scintigraphy using [99mTc]MAA (MAA) was also done. Although early IMP images showed the same findings as [99mTc]MAA, images, a discrepancy between delayed IMP images and [99mTc]MAA images was seen in some patients. Increment of activities seen in late images was demonstrated in most patients whose chest x-ray findings included exudative inflammatory changes. Uptake and clearance of IMP was considered to be affected by the active phase of pulmonary tuberculosis.
authors.affiliation: Department of Radiology, Miyazaki Medical College, Miyazakiken, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Nagamachi
authors.forename: K
authors.initials: K
authors.lastname: Inoue
authors.forename: H
authors.initials: H
authors.lastname: Hoshi
authors.forename: S
authors.initials: S
authors.lastname: Jinnouchi
authors.forename: T
authors.initials: T
authors.lastname: Ohonishi
authors.forename: S
authors.initials: S
authors.lastname: Futami
authors.forename: K
authors.initials: K
authors.lastname: Watanabe
authors.forename: M
authors.initials: M
authors.lastname: Wakisaka
authors.forename: Y
authors.initials: Y
authors.lastname: Morotomi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000662:Amphetamines; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging / Q000379:methods; D013668:Technetium Tc 99m Aggregated Albumin; D014397:Tuberculosis, Pulmonary / Q000000981:diagnostic imaging*
chemical_list: D000662:Amphetamines; D007457:Iodine Radioisotopes; D013668:Technetium Tc 99m Aggregated Albumin; C041336:4-iodoamphetamine