title: Stereotactic linac radiosurgery for arteriovenous malformations.
abstract: Stereotactic linear accelerator (linac) radiosurgery has been in operation in the West Midlands since 1987, the first of its kind in the United Kingdom. Forty two patients with high-flow cerebral arteriovenous malformations have been treated, 26 of whom have been followed up. Angiography one year after treatment showed that five lesions were obliterated, 11 were reduced in size and/or flow rate and 10 were unchanged. Overall results show that nine out of 10 patients reviewed at 24 months had total obliteration. Three patients had complications; one has fully recovered, one died of an unrelated cause at 36 months and the other died from recurrent haemorrhage at nine months. Two patients had recurrent non-fatal haemorrhage within 24 months of treatment; both recovered without further deficit. All patients are fit to work but eight are unemployed. Although the follow up period is short, the early results indicate a success rate similar to those published by others using linac radiosurgery.
authors.affiliation: University of Birmingham, Midland Centre for Neurosurgery and Neurology, UK.
authors.forename: B G
authors.initials: BG
authors.lastname: Kenny
authors.forename: E R
authors.initials: ER
authors.lastname: Hitchcock
authors.forename: G
authors.initials: G
authors.lastname: Kitchen
authors.forename: A E
authors.initials: AE
authors.lastname: Dalton
authors.forename: D A
authors.initials: DA
authors.lastname: Yates
authors.forename: S V
authors.initials: SV
authors.lastname: Chavda
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002533:Cerebral Angiography / Q000295:instrumentation; D002543:Cerebral Hemorrhage / Q000175:diagnosis / Q000601:surgery; D002648:Child; D003199:Computer Systems; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000175:diagnosis / Q000601:surgery*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis; D016634:Radiosurgery / Q000295:instrumentation*; D011880:Radiotherapy Planning, Computer-Assisted / Q000295:instrumentation; D013238:Stereotaxic Techniques / Q000295:instrumentation*; D014057:Tomography, X-Ray Computed / Q000295:instrumentation