title: Sarcoidosis with tumorous hepatic and bone lesions mimicking disseminated malignancy: a case report.
abstract: An asymptomatic 49-year-old woman with a diffuse abnormal shadow detected on a routine chest rentogenogram was referred for evaluation. Ultrasonography, computed tomography (CT) and magnetic resonance imaging (MRI) revealed space-occupying lesions in the liver and spleen. Lymphadenopathy was observed in the mediastinum and abdomen on CT, and multiple lesions of low signal intensity were observed in the spine on MRI. Furthermore, the presence of multiple tumorous nodules in the liver suggesting metastatic hepatic cancer was demonstrated on laparoscopy. Biopsy of the liver tumors revealed sarcoidosis; transbronchial biopsy specimens showed identical histological features. After administration of prednisolone for one month, the space-occupying lesions in the liver, spleen and spine improved. This case of sarcoidosis exhibited hepatic tumorous nodules and space-occupying lesions in the spleen and the spine which mimicked the presence of metastatic hepatic cancer.
authors.affiliation: Second Department of Internal Medicine, Faculty of Medicine, Kagoshima University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Oketani
authors.forename: H
authors.initials: H
authors.lastname: Tsubouchi
authors.forename: T
authors.initials: T
authors.lastname: Hori
authors.forename: K
authors.initials: K
authors.lastname: Sakamoto
authors.forename: S
authors.initials: S
authors.lastname: Kawakami
authors.forename: N
authors.initials: N
authors.lastname: Yoshimitsu
authors.forename: T
authors.initials: T
authors.lastname: Matsuo
authors.forename: S
authors.initials: S
authors.lastname: Hirono
authors.forename: Y
authors.initials: Y
authors.lastname: Shimoide
authors.forename: T
authors.initials: T
authors.lastname: Miura
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D012507:Sarcoidosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D013122:Spinal Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D013158:Splenic Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed