Intravenous gamma-globulin therapy in Diamond-Blackfan anemia.
Pure red cell aplasia (PRCA) is a rare disorder of erythrocyte production which is believed to have an autoimmune basis in most cases. Diamond-Blackfan anemia (DBA) is one type of congenital PRCA. Since PRCA has been reported to respond to intravenous gamma-globulin (IVGG) therapy, we administered IVGG to a 2 year old girl with DBA resistant to corticosteroids and observed slight therapeutic effect.
Sumimoto
S
S
Department of Pediatrics, Sumitomo Hospital, Osaka, Japan.
Kawai
M
M
Kasajima
Y
Y
Hamamoto
T
T
D000305:Adrenal Cortex Hormones / Q000009:adverse effects / Q000627:therapeutic use*; D001803:Blood Transfusion; D002675:Child, Preschool; D005199:Fanconi Anemia / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use*; D012010:Red-Cell Aplasia, Pure / Q000097:blood* / Q000151:congenital / Q000188:drug therapy
D000305:Adrenal Cortex Hormones; D016756:Immunoglobulins, Intravenous