title: Favorable experience with pre-emptive renal transplantation in children.
abstract: We retrospectively examined our experience with live-related donor kidney transplants in 66 children during the 7-year period 1984-1990. We compared the clinical courses of 26 children who did not receive any dialytic therapy prior to transplantation with 40 children who were dialyzed (27 via peritoneal dialysis and 13 via hemodialysis). We did not find any statistically significant differences in patient or graft survival between these three groups with a follow-up period of 6-87 months. Based on our results, we conclude that pre-emptive transplantation is an acceptable treatment for children who will inevitably require renal replacement therapy.
authors.affiliation: Department of Pediatrics, Northwestern University Medical School, Chicago, Illinois.
authors.forename: L S
authors.initials: LS
authors.lastname: Flom
authors.forename: E M
authors.initials: EM
authors.lastname: Reisman
authors.forename: J M
authors.initials: JM
authors.lastname: Donovan
authors.forename: M R
authors.initials: MR
authors.lastname: Zaontz
authors.forename: J
authors.initials: J
authors.lastname: Stein
authors.forename: C F
authors.initials: CF
authors.lastname: Firlit
authors.forename: R A
authors.initials: RA
authors.lastname: Cohn
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000453:epidemiology / Q000601:surgery / Q000628:therapy; D016030:Kidney Transplantation / Q000592:standards*; D008297:Male; D010530:Peritoneal Dialysis; D006435:Renal Dialysis; D012189:Retrospective Studies; D013223:Statistics as Topic; D013997:Time Factors