title: [Clinical evaluation of traditional Chinese medicine for chronic idiopathic thrombocytopenic purpura].
abstract: The efficacy of traditional Chinese medicine (Kampo medicine) was examined in 40 patients with steroid-unresponsive idiopathic thrombocytopenic purpura (ITP). All patients were, at first, given Hochuekihi-to, and when they were refractory, therapy was switched to Sairei-to, Ninjinyoei-to, and Kamikihi-to. The efficacy rate was 20.0% by Hochuekihi-to, 20.7% by Sairei-to, 5.5% by Ninjinyoei-to and 6.7% by Kamikihi-to, respectively. Thus, overall responders were 12 in 40 patients with an effective rate of 30.0%. The mechanism of action of traditional Chinese medicine is discussed in relation to the production of various kinds of cytokines.
authors.affiliation: Department of Immunohematology, Kobe City General Hospital.
authors.forename: S
authors.initials: S
authors.lastname: Nakayama
authors.forename: A
authors.initials: A
authors.lastname: Matsushita
authors.forename: S
authors.initials: S
authors.lastname: Ichiba
authors.forename: H
authors.initials: H
authors.lastname: Yabe
authors.forename: K
authors.initials: K
authors.lastname: Nagai
mesh_terms: D000328:Adult; D000368:Aged; D004341:Drug Evaluation; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000188:drug therapy*
chemical_list: D004365:Drugs, Chinese Herbal