Involvement of PAF in atherogenesis. Brief review.
Crucial points have been recently explored between formation, release and breakdown of PAF and atherosclerotic plaque formation. Experimental and clinical studies suggest that an autocatalytic feedback network among PAF, cytokines and growth factors contributes to atherogenesis. This novel approach to atherogenesis deserves future therapeutical importance.
Koltai
M
M
Institut Henri Beaufour, Le Plessis Robinson, France.
Braquet
P G
PG
D000818:Animals; D001161:Arteriosclerosis / Q000503:physiopathology*; D006801:Humans; D010972:Platelet Activating Factor / Q000502:physiology*
D010972:Platelet Activating Factor