Blood rheology after LDL apheresis using dextran sulfate cellulose absorption--a case report.
The authors describe a thirty-eight-year-old woman with familial hypercholesterolemia treated by dextran sulfate cellulose adsorption apheresis. This technique and the selective extracorporeal LDL cholesterol elimination by immunoabsorption or heparin-induced precipitation not only dramatically decrease blood lipids but also result in a marked improvement in the rheologic profile. It is suggested that the amelioration of blood rheology by LDL apheresis may represent the cause for the early clinical improvement felt by most patients with severe coronary heart disease and hypercholesterolemia.
Koenig
W
W
Department of Internal Medicine, University of Ulm, Germany.
Ditschuneit
H H
HH
Hehr
R
R
Grunewald
R W
RW
Ernst
E
E
Hombach
V
V
D000327:Adsorption; D000328:Adult; D001781:Blood Component Removal / Q000379:methods; D001809:Blood Viscosity; D002482:Cellulose; D008078:Cholesterol, LDL / Q000097:blood; D016264:Dextran Sulfate; D005260:Female; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000097:blood / Q000628:therapy*; D012212:Rheology
D008078:Cholesterol, LDL; D002482:Cellulose; D016264:Dextran Sulfate