title: Audiological, vestibular and radiological abnormalities in Kallman's syndrome.
abstract: Kallman's syndrome is a multifaceted congenital disorder with predominantly endocrine abnormalities. We have characterized the associated mixed hearing loss and identified consistent radiological evidence of abnormal temporal bone anatomy. Abnormal labyrinthine morphology is accompanied by a complete absence of response to vestibular stimulation with caloric or rotational chair testing. The endocrine abnormalities are correctable and Kallman's syndrome is a diagnosis worthy of consideration when assessing children with congenital hearing loss.
authors.affiliation: Department of Otolaryngology, Freeman Hospital, Newcastle upon Tyne.
authors.forename: J
authors.initials: J
authors.lastname: Hill
authors.forename: C
authors.initials: C
authors.lastname: Elliott
authors.forename: I
authors.initials: I
authors.lastname: Colquhoun
mesh_terms: D000328:Adult; D005260:Female; D006062:Gonadotropins / Q000172:deficiency*; D034381:Hearing Loss / Q000151:congenital* / Q000503:physiopathology; D006320:Hearing Tests; D006801:Humans; D008297:Male; D000857:Olfaction Disorders / Q000209:etiology; D013577:Syndrome; D014057:Tomography, X-Ray Computed; D014724:Vestibular Function Tests
chemical_list: D006062:Gonadotropins