[Profile of pO2. I. Profile of transretinal pO2 in hypoxia].
Transretinal PO2 measurements during systemic hypoxia, made during variations of the PO2 by steps of 10 mmHg between 120 and 30 mmHg, have shown that the PO2 values measured at the inner-retina up to half the thickness of the retina remained stable. On the other hand, those measured at the choroid and at the outer-retina decreased in a linear manner according to the variations of PaO2. These results suggest a regulation in the retinal blood flow, allowing the PO2 to remain stable for the different steps of hypoxia studied. On the other hand, the values measured at the choroid and at the outer-retina showed the absence of regulation in the choroidal blood flow during hypoxia. Systemic hypoxia may affect the metabolism of the photoreceptors and the pigmentary epithelium.
Moret
P
P
Clinique d'Ophtalmologie, Universitaire Genève.
Pournaras
C J
CJ
Munoz
J L
JL
Brazitikos
P
P
Tsacopoulos
M
M
D000818:Animals; D001813:Blood-Retinal Barrier / Q000502:physiology*; D004596:Electroretinography; D000860:Hypoxia / Q000097:blood*; D010100:Oxygen / Q000097:blood*; D012160:Retina / Q000378:metabolism*; D013552:Swine; D013556:Swine, Miniature
D010100:Oxygen
Profils de la PO2. I. Profils de la PO2 transrétinienne en hypoxie.