[Infectious agents and autoimmune diseases].
In this paper the molecular aspects of the relationships between infectious agents and autoimmune diseases, the mechanisms of immune response to infectious agents, and the more recent hypotheses regarding the cause of autoimmune diseases are discussed. The antigens are processed and selected by their immunogenicity, and presented by HLA molecules to the T cell receptor. These events initiate the immune response with the activation and proliferation of T-lymphocytes. Although there are several hypotheses regarding the cause of autoimmune diseases and too many findings against and in favor of them, there is still no conclusive data. All these hypothesis and findings are discussed in the context of the more recent advances.
Riebeling-Navarro
C
C
Servicio de Reumatología, Hospital General de Zona No. 1, Instituto Mexicano del Seguro Social, México, D.F.
Madrid-Marina
V
V
Camarena-Medellín
B E
BE
Peralta-Zaragoza
O
O
Barrera
R
R
D000942:Antigens, Bacterial / Q000276:immunology; D001327:Autoimmune Diseases / Q000209:etiology* / Q000276:immunology; D006680:HLA Antigens / Q000276:immunology; D006801:Humans; D007239:Infections / Q000150:complications*; D011971:Receptors, Immunologic; D012216:Rheumatic Diseases / Q000209:etiology; D013601:T-Lymphocytes / Q000276:immunology; D014397:Tuberculosis, Pulmonary / Q000209:etiology
D000942:Antigens, Bacterial; D006680:HLA Antigens; D011971:Receptors, Immunologic
Agentes infecciosos y enfermedades autoinmunes.