Flunarizine--effective add-on therapy in reading epilepsy.
Since it was first described in 1956, reading epilepsy, an uncommon disorder, has engendered great interest among neurologists, the reason being that it is probably one of the most complex of the sensory-evoked reflex epilepsies and one in which the mechanism of seizure production is as yet unresolved. Unfortunately, it often defies the standard medications useful in the treatment of other forms of epilepsy. A patient with typical reading epilepsy, preceded by jaw-jerking, is described in this report. An additional feature of this case is the presence of a stutter from early childhood. Therapy with phenytoin, carbamazepine and sodium valproate failed to provide satisfactory control. Flunarizine, as add-on therapy to sodium valproate, produced an excellent therapeutic response.
Durrheim
D N
DN
Department of Neurology, Medical University of Southern Africa, PO Medunsa.
Joubert
J
J
Griesel
R D
RD
D000328:Adult; D004359:Drug Therapy, Combination; D004569:Electroencephalography; D004827:Epilepsy / Q000188:drug therapy* / Q000209:etiology; D005444:Flunarizine / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D011932:Reading; D014635:Valproic Acid / Q000008:administration & dosage*
D014635:Valproic Acid; D005444:Flunarizine