[Antibodies against mycobacterial antigens in patients with non-tuberculous pathology].
Antibodies (type IgG) against the A 60 antigen (Mycobacterium bovis, BCG) and an antigen of Mycobacterium tuberculosis were studied by ELISA in 79 patients with not tuberculous disease: 16 lung carcinoma, 16 hepatic cirrhosis and 47 patients with pulmonary disease. 59.5% and 50.6% of the patients showed antibodies against antigen A 60 and M. tuberculosis antigen respectively; more 25% were strongly positive against antigen A 60; in the patients with lung carcinoma this results were 62.5%. It is concluded than when this methods are use in the serologic diagnostic of tuberculosis the number of cirrhotic and not tuberculous pulmonary disease patients with antibodies against this antigens, obliges a careful study of the individual characteristics of each patient, and it is very important previously to discard a lung neoplastic pathology.
Ladrón de Guevara
M C
MC
Servicio de Microbiología, Hospital La Paz, Madrid.
González
A
A
Saz
J V
JV
D000907:Antibodies, Bacterial / Q000097:blood* / Q000276:immunology; D000942:Antigens, Bacterial / Q000276:immunology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008562:Membrane Glycoproteins / Q000276:immunology*; D009163:Mycobacterium bovis / Q000276:immunology*
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D007074:Immunoglobulin G; D008562:Membrane Glycoproteins; C055539:mycobacterial A60 antigen
Anticuerpos frente a antígenos micobacterianos en enfermos con patología no tuberculosa.