Pituitary and gonadal functions in patients with chordee without hypospadias.
Pituitary and gonadal functions in 16 prepubertal boys with chordee without hypospadias by stimulation of gonadotropin releasing hormone or human chorionic gonadotropin were compared to those of age-matched normal boys. The patients with chordee without hypospadias had poor follicular stimulating hormone response but pituitary luteinizing hormone reserve function was normal. Testosterone response by stimulation of human chorionic gonadotropin was not impaired in patients with chordee without hypospadias. The results suggested that chordee without hypospadias may also be categorized into hypospadias from the aspect of its pituitary and gonadal functions in addition to the embryogenesis of chordee.
Shima
H
H
Department of Urology, Hyogo College of Medicine, Japan.
Okamoto
E
E
Ikoma
F
F
D002675:Child, Preschool; D006063:Chorionic Gonadotropin; D007987:Gonadotropin-Releasing Hormone; D006065:Gonadotropins, Pituitary / Q000378:metabolism*; D006801:Humans; D007021:Hypospadias; D007985:Leydig Cells / Q000502:physiology*; D008297:Male; D010409:Penile Diseases / Q000503:physiopathology*; D010903:Pituitary Gland, Anterior / Q000503:physiopathology*
D006063:Chorionic Gonadotropin; D006065:Gonadotropins, Pituitary; D007987:Gonadotropin-Releasing Hormone