title: Exocytosis upon osmotic swelling in human epithelial cells.
abstract: Upon osmotic swelling human epithelial cells exhibited significant increases in the membrane capacitance. Evidence for exocytosis includes its dependency on temperature, cytosolic Ca2+ and ATP as well as its sensitivity to guanosine 5'-O-(3-thio)triphosphate (GTP gamma S) and N-ethylmaleimide (NEM). A role of the osmotic exocytosis in the subsequent cell volume regulation is suggested.
authors.affiliation: Department of Physiology, Kyoto University Faculty of Medicine, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Okada
authors.forename: A
authors.initials: A
authors.lastname: Hazama
authors.forename: A
authors.initials: A
authors.lastname: Hashimoto
authors.forename: Y
authors.initials: Y
authors.lastname: Maruyama
authors.forename: M
authors.initials: M
authors.lastname: Kubo
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D002118:Calcium / Q000378:metabolism; D002460:Cell Line; D002462:Cell Membrane / Q000502:physiology*; D004553:Electric Conductivity; D004848:Epithelium / Q000502:physiology; D005089:Exocytosis; D006801:Humans; D009997:Osmotic Pressure; D013696:Temperature
chemical_list: D000255:Adenosine Triphosphate; D002118:Calcium