title: Excitement in synovium: the rapid evolution of understanding of rheumatoid arthritis and expectations for therapy.
abstract: Multiple events give rise to rheumatoid arthritis (RA) and many different elements create an overall pathological effect. It is highly unlikely that a single cause for RA will be identified. A greater appreciation of the multiple events that lead to the development of RA is opening up a number of promising points of intervention which may serve as potential alternatives to the broader-based and often toxic drugs used in RA therapy today.
authors.affiliation: Department of Medicine, Stanford University School of Medicine, CA 94305-5109.
authors.forename: E D
authors.initials: ED
authors.lastname: Harris
mesh_terms: D000941:Antigens / Q000276:immunology; D001172:Arthritis, Rheumatoid / Q000209:etiology* / Q000276:immunology / Q000628:therapy; D006801:Humans; D007167:Immunotherapy; D008213:Lymphocyte Activation; D008954:Models, Biological; D009504:Neutrophils / Q000502:physiology; D013583:Synovial Membrane / Q000276:immunology / Q000473:pathology / Q000502:physiology*; D013601:T-Lymphocytes / Q000502:physiology
chemical_list: D000941:Antigens