title: [Septic granulomatosis (chronic granulomatous disease = CGD) in the jaw area. A case report].
abstract: A rare case of chronic granulomatous disease with manifestation in the mandible is presented. A 10-year-old boy showed the clinical picture of osteomyelitis without paresthesia (Vincent syndrome). Diagnosis was done by the nitroblue tetrazolium test (NBT) and by demonstration of a complete cytochrome-b deficiency of the granulocytes. In septic granulomatosis a continuous application of Sulfamethoxazol-Trimetoprim is recommended for prophylaxis of infection. For treatment of infection further antibiotics who pass into the granulocytes like rifampicin and fosfomycin are necessary. Oral surgical procedures request a careful tissue handling and a tight wound closure.
authors.affiliation: Klinik und Poliklinik für Mund-Kiefer-Gesichtschirurgie, Heidelberg, Bundesrepublik Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Herrmann
authors.forename: J
authors.initials: J
authors.lastname: Zöller
authors.forename: T
authors.initials: T
authors.lastname: Böhler
authors.forename: I A
authors.initials: IA
authors.lastname: Born
mesh_terms: D002648:Child; D003131:Combined Modality Therapy; D003573:Cytochrome b Group / Q000172:deficiency; D006105:Granulomatous Disease, Chronic / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D006801:Humans; D008297:Male; D008334:Mandible / Q000000981:diagnostic imaging / Q000473:pathology; D008336:Mandibular Diseases / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D009580:Nitroblue Tetrazolium; D010019:Osteomyelitis / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D011862:Radiography, Panoramic
chemical_list: D003573:Cytochrome b Group; D009580:Nitroblue Tetrazolium
vernacular_title: Die septische Granulomatose (chronic granulomatous disease = CGD) im Kieferbereich. Ein Fallbericht.