Corneal melting after pterygium removal followed by topical mitomycin C therapy.
Right corneal melting and scleral necrosis developed in a 77-year-old man 5 months after pterygium excision followed by topical administration of mitomycin C drops (0.4 mg/mL) for 4 weeks. We believe that these were delayed complications of the mitomycin C therapy, and we caution against prolonged use of the drug postoperatively.
Ewing-Chow
D A
DA
Department of Ophthalmology, Royal University Hospital, Saskatoon.
Romanchuk
K G
KG
Gilmour
G R
GR
Underhill
J H
JH
Climenhaga
D B
DB
D000287:Administration, Topical; D000368:Aged; D003315:Cornea / Q000473:pathology*; D006801:Humans; D015948:Keratoplasty, Penetrating; D008297:Male; D016685:Mitomycin / Q000008:administration & dosage / Q000009:adverse effects*; D009336:Necrosis / Q000139:chemically induced; D011183:Postoperative Complications / Q000517:prevention & control; D011625:Pterygium / Q000517:prevention & control / Q000601:surgery*; D012008:Recurrence; D012590:Sclera / Q000473:pathology; D014792:Visual Acuity
D016685:Mitomycin