Flow cytometric and genetic study of familial gonadal tumors.
Three cases of familial gonadal tumors are reported. Genetic studies were conducted in 2 cases: a brother and sister with embryonal carcinoma and a benign cystic teratoma, respectively, and a father and son with embryonal carcinoma. DNA flow cytometry of paraffin-embedded tumors and constitutional karyotyping were performed. Further genetic studies are emphasized.
Leventhal
A M
AM
Department of Urology, New York University Medical Center, New York.
Camuto
P
P
Hajjar
J
J
Wolman
S R
SR
Plawner
J
J
D000328:Adult; D004273:DNA, Neoplasm / Q000032:analysis*; D005260:Female; D005434:Flow Cytometry; D005833:Genital Neoplasms, Female / Q000737:chemistry / Q000235:genetics* / Q000473:pathology; D005834:Genital Neoplasms, Male / Q000737:chemistry / Q000235:genetics* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree
D004273:DNA, Neoplasm