title: Blood flow and metabolic therapy in CNS injury.
abstract: A hypermetabolic state, consisting of increased resting energy expenditure, excessive protein wasting, and hyperglycemia, occurs in patients with a severe head injury. The hypermetabolism can affect survival by rapidly resulting in protein-calorie malnutrition (increased energy expenditure and protein wasting) and may adversely affect neurological recovery by altering the microenvironment of the injured brain (hyperglycemia).
authors.affiliation: Department of Neurosurgery, Baylor College of Medicine, Houston, Texas.
authors.forename: C S
authors.initials: CS
authors.lastname: Robertson
authors.forename: J C
authors.initials: JC
authors.lastname: Goodman
authors.forename: R G
authors.initials: RG
authors.lastname: Grossman
mesh_terms: D000818:Animals; D001921:Brain / Q000098:blood supply / Q000378:metabolism / Q000503:physiopathology*; D001930:Brain Injuries / Q000178:diet therapy* / Q000378:metabolism / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D004734:Energy Metabolism; D006801:Humans; D006943:Hyperglycemia / Q000209:etiology / Q000517:prevention & control; D007328:Insulin / Q000627:therapeutic use; D012039:Regional Blood Flow; D016896:Treatment Outcome
chemical_list: D007328:Insulin