Skin cancers and HLA frequencies in renal transplant recipients.
An association between HLA DR7 and the development of multiple non-melanoma skin cancer was detected in immunosuppressed patients in southern Australia. The relative risk was 2.6 which was lower than for immunocompetent patients with the same skin cancers. HLA frequencies of renal transplant recipients with multiple skin cancers were determined. The types HLA B27 and HLA Dr7 were found in significantly higher frequency, and there was no absence of HLA A11.
Czarnecki
D
D
Repatriation General Hospital, Heidelberg, Australia.
Watkins
F
F
Leahy
S
S
Dyall-Smith
D
D
Levis
A
A
Nicholson
I
I
Tait
B
B
D000328:Adult; D000368:Aged; D002280:Basal Cell Carcinoma / Q000276:immunology*; D002294:Carcinoma, Squamous Cell / Q000276:immunology*; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D015796:HLA-B27 Antigen / Q000032:analysis; D015809:HLA-DR7 Antigen / Q000032:analysis; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000276:immunology*
D006680:HLA Antigens; D015796:HLA-B27 Antigen; D015809:HLA-DR7 Antigen