Lingual localization of an inclusion body fibromatosis (Reye's tumor).
This report illustrates a lingual localization of an inclusion body fibromatosis, the so-called Reye tumor or infantile digital fibromatosis (IDF). The light microscopic features were identical to those found in IDF, showing eosinophilic perinuclear inclusions located in spindle-shaped cells arranged in interlacing fascicles. The immunocytochemical and ultrastructural findings suggested a fibroblastic and/or myofibroblastic nature of the proliferative cells. However, the inclusions in our case were strongly stained with vimentin and their ultrastructural appearance was in keeping with intermediate filaments. These findings have never been described in other reports of fibromatosis. Whereas most reviews state that IDF occurs exclusively on the digits, this unique case describes its possible occurrence in the tongue.
Canioni
D
D
Groupe de Pathologie Pédiatrique, Hôpital des Enfants Malades, Paris, France.
Richard
S
S
Rambaud
C
C
Manach
Y
Y
Nezelof
C
C
D005350:Fibroma / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D002479:Inclusion Bodies / Q000648:ultrastructure*; D007223:Infant; D008297:Male; D008854:Microscopy, Electron; D014062:Tongue Neoplasms / Q000378:metabolism / Q000473:pathology*