Renal tissue mast cells in liver diseases.
Renal tissue mast cell counts were studied in autopsied cases of liver diseases. In cirrhosis and fibrosis of the liver, cases with hepato-renal syndrome showed a significant decrease in renal tissue mast cell counts as compared to those without hepato-renal syndrome. On the other hand, a significant increase in the number of mast cells was noted in cases with hepato-renal syndrome as compared to those without hepato-renal syndrome in fulminant hepatitis. These results suggest that renal tissue mast cells may play an important role in the onset of acute renal failure in liver diseases.
Yoshimura
A
A
Department of Pathology, Faculty of Medicine, University of Tokyo, Japan.
Mori
W
W
D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000473:pathology; D005260:Female; D006530:Hepatorenal Syndrome / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology*; D008103:Liver Cirrhosis / Q000150:complications / Q000473:pathology; D008107:Liver Diseases / Q000473:pathology*; D008113:Liver Neoplasms / Q000150:complications / Q000473:pathology; D008297:Male; D008407:Mast Cells / Q000473:pathology*; D008875:Middle Aged