title: A rational system for classifying and denominating adenovirus genome types.
abstract: We propose to classify "genome types" of human adenoviruses in the same way as the "genomic clusters" defined by Li and Wadell, i.e. groups of closely related DNA variants of a given serotype named by the use of indices, P (standing for prototype) a, b etc. Variants within the genome type are named by letter-number indices (p1, p2; a1, a2 etc.). The percentage of comigrating restriction fragments and common restriction sites is significantly higher in variants than between genome types. The new naming system is applicable to adenoviruses from 5 subgenera, but requires additional work for subgenus C strains. Renaming is required mainly for adenovirus 7.
authors.affiliation: Abteilung für Virologie, Universitätskliniken, Homburg/Saar, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Wigand
authors.forename: T
authors.initials: T
authors.lastname: Adrian
mesh_terms: D000260:Adenoviruses, Human / Q000145:classification* / Q000235:genetics; D004262:DNA Restriction Enzymes; D004279:DNA, Viral / Q000145:classification / Q000235:genetics; D005814:Genes, Viral; D014644:Genetic Variation; D012703:Serotyping
chemical_list: D004279:DNA, Viral; D004262:DNA Restriction Enzymes