title: Radon exposure system for mammalian cells in culture: design, operation, and dosimetry.
abstract: A novel system for Rn gas exposure of mammalian cells in culture has been designed, constructed, and used to directly assess both the magnitude and the nature of chronic, low-dose Rn/Rn daughter toxicity of exposed vital lung cells isolated from normal pulmonary tissue, propagated and exposed in vitro. Direct correlations between atmospheric Rn concentrations, alpha-particle fluences, and macro- and microdoses of absorbed radiation doses by lung cells provide for a heretofore unavailable assessment of critical doses to vital cells.
authors.affiliation: Biological and Medical Research Division, Argonne National Laboratory, IL 60439.
authors.forename: T M
authors.initials: TM
authors.lastname: Seed
authors.forename: N D
authors.initials: ND
authors.lastname: Kretz
authors.forename: R A
authors.initials: RA
authors.lastname: Schlenker
mesh_terms: D000396:Air Pollutants, Radioactive; D001729:Bismuth; D002470:Cell Survival / Q000528:radiation effects; D002478:Cells, Cultured; D004307:Dose-Response Relationship, Radiation; D005347:Fibroblasts / Q000528:radiation effects; D006801:Humans; D066298:In Vitro Techniques; D007854:Lead; D008168:Lung / Q000166:cytology / Q000528:radiation effects*; D011059:Polonium; D011829:Radiation Dosage; D011886:Radon; D017687:Radon Daughters
chemical_list: D000396:Air Pollutants, Radioactive; D017687:Radon Daughters; D007854:Lead; D011059:Polonium; D011886:Radon; D001729:Bismuth