title: [Clinical analysis of eight cases treated with lateral skull base surgery].
abstract: Eight cases were treated by lateral skull base surgery. Three benign tumors (2: paraganglioma, 1: neurinoma) originated from parapharyngeal space and infiltrated into jugular foramen, and five malignant tumors (3: squamous cell carcinoma, 1: adenoid cystic carcinoma, 1: rhabdomyosarcoma) involved the skull base. Preoperative magnetic resonance imaging gives information as to whether tumors invaded to cranial bone or not, and also permits deciding surgical procedures. Surgical management of mandibular bone was performed in five cases for complete tumor resection and sufficient surgical view; hemimandibulectomy was carried out in four malignant cases, who simultaneously underwent radical neck dissection, and one benign case underwent mandiblotomy. Ligation of sigmoid sinus was carried out in four cases (1; benign, 3; malignant) to control bleeding from large vessels. The skull base was reconstructed with myocutaneous flaps which were fixed by fibrin tissue adhesive. No significant surgical complications were not noted. There were no recurrence of benign tumor during 8-13 years follow up period. Malignant tumors, except one (rhabdomyosarcoma), had no local recurrence during follow up period (4 months-2 years). We emphasize that the progress in preoperative assessment, as well as in reconstructive surgical techniques, will assure more adequate indication of lateral skull surgery for malignant tumors.
authors.affiliation: Department of Otolaryngology, Asahikawa Medical School.
authors.forename: M
authors.initials: M
authors.lastname: Takahashi
authors.forename: T
authors.initials: T
authors.lastname: Kamito
authors.forename: N
authors.initials: N
authors.lastname: Hatayama
authors.forename: H
authors.initials: H
authors.lastname: Shinohara
authors.forename: H
authors.initials: H
authors.lastname: Miyouga
authors.forename: T
authors.initials: T
authors.lastname: Ogino
authors.forename: T
authors.initials: T
authors.lastname: Unno
mesh_terms: D000328:Adult; D000368:Aged; D003528:Carcinoma, Adenoid Cystic / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000601:surgery; D003399:Craniotomy / Q000379:methods*; D005260:Female; D015718:Fibrin Tissue Adhesive; D006801:Humans; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection; D010236:Paraganglioma, Extra-Adrenal / Q000601:surgery; D010610:Pharyngeal Neoplasms / Q000601:surgery; D012208:Rhabdomyosarcoma / Q000601:surgery; D012888:Skull Neoplasms / Q000601:surgery*; D013524:Surgical Flaps
chemical_list: D015718:Fibrin Tissue Adhesive