Restoration of the defective natural defence of beige mice against tissue-migrating larvae of Strongyloides ratti by transfer with normal peritoneal cells.
The effects of cell transfer on the defective natural defences of beige (bgj/bgj) mice against Strongyloides ratti were studied by assessing recovery of tissue-migrating larvae from head and lung. Transfer of peritoneal resident cells from normal bgj/+ mice restored the defective natural defence of beige mice. The non-adherent population of normal peritoneal cells did not have the restorative capacity. Macrophages may be important to the natural defence against S. ratti.
Abe
T
T
Department of Parasitology, Akita University School of Medicine, Japan.
Yoshimura
K
K
Nawa
Y
Y
D000818:Animals; D007113:Immunity, Innate; D016219:Immunotherapy, Adoptive; D008264:Macrophages / Q000276:immunology*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D013321:Strongyloides / Q000276:immunology*; D013322:Strongyloidiasis / Q000628:therapy*