Chromosomal translocation t(1;13)(p36;q14) in a case of rhabdomyosarcoma.
Cytogenetic studies of a rhabdomyosarcoma of mixed embryonal and alveolar histology in an 11-month-old male revealed a single structural abnormality, t(1;13)(p36;q14). This abnormality may define a subset of patients with a variant of the t(2;13)(q35;q14) translocation frequently seen in alveolar rhabdomyosarcoma.
Biegel
J A
JA
Division of Human Genetics and Molecular Biology, Children's Hospital of Philadelphia, PA 19104.
Meek
R S
RS
Parmiter
A H
AH
Conard
K
K
Emanuel
B S
BS
D002878:Chromosomes, Human, Pair 1 / Q000648:ultrastructure*; D002882:Chromosomes, Human, Pair 13 / Q000648:ultrastructure*; D006801:Humans; D007223:Infant; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000235:genetics* / Q000473:pathology; D012208:Rhabdomyosarcoma / Q000235:genetics* / Q000473:pathology; D012983:Soft Tissue Neoplasms / Q000235:genetics* / Q000473:pathology; D013848:Thigh; D014178:Translocation, Genetic