[Serum angiotensin converting enzyme in the diagnosis of sarcoidosis and other lung diseases].
The serum angiotensin-converting enzyme activity (ACE) was studied in 198 patients (116 had sarcoidosis and 82 pulmonary diseases with sarcoidosis-like X-ray picture). Rise of ACE activity in sarcoidosis patients was clearly associated with the process phase (93% in active sarcoidosis and 35.7% in nonactive). Rise of serum ACE activity was found in 46.3% of the patients having sarcoidosis-like diseases (in 41% with tuberculosis 56.3% with nonspecific inflammatory diseases and also in patients with fibrosing alveolitis, histiocytosis X and pneumoconiosis). Though the blood serum ACE activity has a high rate of the increase in sarcoidosis, this test should be considered only in the general complex of differential diagnosis signs. This can be explained by a sufficiently high probability of ACE activity rise in all diseases that most commonly require differentiation with sarcoidosis.
Adamovich
V N
VN
Borisov
S E
SE
Zubkov
A A
AA
Danilov
S M
SM
Sakharov
I Iu
IIu
Atochina
E N
EN
D000293:Adolescent; D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D004789:Enzyme Activation / Q000502:physiology; D005260:Female; D006801:Humans; D008171:Lung Diseases / Q000175:diagnosis / Q000201:enzymology*; D008175:Lung Neoplasms / Q000175:diagnosis / Q000201:enzymology*; D008297:Male; D008875:Middle Aged; D007703:Peptidyl-Dipeptidase A / Q000097:blood*; D012507:Sarcoidosis / Q000175:diagnosis / Q000201:enzymology*; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000201:enzymology*
D007703:Peptidyl-Dipeptidase A
Angiotenzinprevrashchaiushchiĭ ferment syvorotki krovi v diagnostike sarkoidoza i drugikh zabolevaniĭ legkikh.