[The modification of the cyclic activity of the isolated spinal cord in l6- to 20-day-old chick embryos through changes in the Ca2+ and Mg2+ concentrations].
Spontaneous rhythmic activity which appeared as synchronous oscillations of electrotonic potentials in dorsal and ventral roots (DR and VR, respectively) of isolated spinal cord sections of 16-20-day-old chick embryos was completely blocked with a rise of Mg2+ concentration from the control level (1.3 mmol/l) to 5 mmol/l. The similar effect was observed when Ca2+ concentration fell from 2.6 to 1 mmol/l, but in that case spike discharges could appear in VR. Moreover, during disappearance of the above spontaneous activity (after changes in Mg2+ or Ca2+ concentration) rhythmic activity of other type was observed in 6 from 8 experiments. That rhythmic activity consisted of oscillations of electrotonic VR potentials (amplitude to 200 microV and duration to 400 ms) which arose irrespective of oscillations of DR potentials. Maximum frequency of that activity was 0.4/s. Possible functional role of the found types of rhythmic activity is discussed.
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D000818:Animals; D002118:Calcium / Q000494:pharmacology*; D002642:Chick Embryo; D004305:Dose-Response Relationship, Drug; D005071:Evoked Potentials / Q000187:drug effects / Q000502:physiology; D066298:In Vitro Techniques; D008274:Magnesium / Q000494:pharmacology*; D009433:Neural Inhibition / Q000187:drug effects / Q000502:physiology; D010477:Perfusion / Q000379:methods; D010507:Periodicity; D013116:Spinal Cord / Q000187:drug effects* / Q000502:physiology; D013126:Spinal Nerve Roots / Q000187:drug effects / Q000502:physiology; D013569:Synapses / Q000187:drug effects / Q000502:physiology; D009435:Synaptic Transmission / Q000187:drug effects / Q000502:physiology; D013997:Time Factors
D008274:Magnesium; D002118:Calcium
Modifikatsiia tsiklicheskoĭ aktivnosti izolirovannogo spinnogo mozga 16--20-dnevnykh kurinykh émbrionov pri izmeneniiakh kontsentratsiĭ Ca2+ i Mg2+.