Two phosphorylation reactions induced by murine beta interferon in BALB/c-3T3 cells.
Treatment with 1000 units/ml of murine beta-interferon enhanced an adenylate kinaselike activity and markedly increased the level of L-alpha-phosphatidyl inositol 4-monophosphate in quiescent BALB/c-3T3 cells. The addition of platelet-derived growth factor (22 units/ml) or poly(I).poly(C) (0.3-1 microgram/ml) to the phosphorylation reaction mixture did not alter this interferon action.
Tominaga
S
S
Department of Biochemistry II, Jichi Medical School, Tochigi, Japan.
D016475:3T3 Cells; D000263:Adenylate Kinase / Q000187:drug effects / Q000378:metabolism*; D000818:Animals; D016899:Interferon-beta / Q000494:pharmacology*; D051379:Mice; D008807:Mice, Inbred BALB C; D010766:Phosphorylation / Q000187:drug effects; D010982:Platelet-Derived Growth Factor / Q000494:pharmacology
D010982:Platelet-Derived Growth Factor; D016899:Interferon-beta; D000263:Adenylate Kinase