[Creatine phosphokinase isoenzymes (CK BB) of the brain in peripheral tissues in schizophrenia].
The activity and content of the brain isoenzyme of creatine phosphokinase-BB (CPK-BB) were investigated in the peripheral tissues containing this isoenzyme (in the small intestine and heart) in health and schizophrenia. The decrease of CPK-BB activity and content in schizophrenic brain was shown before. The present work demonstrates the reduction of CPK-BB activity and concentration not only in the brain of mental patients but also in the intestine and heart tissues. A high correlation was discovered between the CPK-BB level in the brain and in the intestine of schizophrenic patients (r = 0.85).
Aksenova
M V
MV
Karaseva
N S
NS
Burbaeva
G Sh
GSh
D001921:Brain / Q000201:enzymology*; D003402:Creatine Kinase / Q000737:chemistry / Q000172:deficiency / Q000378:metabolism*; D006801:Humans; D007421:Intestine, Small / Q000201:enzymology* / Q000473:pathology; D007527:Isoenzymes; D008875:Middle Aged; D009206:Myocardium / Q000201:enzymology* / Q000473:pathology; D012016:Reference Values; D012559:Schizophrenia / Q000201:enzymology* / Q000473:pathology
D007527:Isoenzymes; D003402:Creatine Kinase
Mozgovaia izoforma kreatinfosfokinazy (KFK BB) v perifericheskikh tkaniakh pri shizofrenii.