title: Synovial sarcoma: a clinicopathological review.
abstract: We have reviewed 20 cases of synovial sarcoma. The main clinical and pathological features of these cases are outlined. Typically these tumours arise in the leg in young adults with a long history before presentation and diagnosis. Clinical and radiological findings are unhelpful in making an early diagnosis. The five year survival rate in this series was 43%. The best guide to prognosis was assessment of mitotic activity. A high index of suspicion is required if the diagnosis is not to be missed. Adequate wide excision of the tumour is the mainstay of treatment.
authors.affiliation: Department of Orthopaedics, Musgrave Park Hospital, Belfast, Northern Ireland.
authors.forename: S A
authors.initials: SA
authors.lastname: Henderson
authors.forename: R
authors.initials: R
authors.lastname: Davis
authors.forename: J R
authors.initials: JR
authors.lastname: Nixon
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001132:Arm; D005260:Female; D006801:Humans; D007866:Leg; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013584:Sarcoma, Synovial / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D015996:Survival Rate