title: A technique for liver biopsy performed in Pekin ducks using anesthesia with Telazol.
abstract: Infection of Pekin ducks with duck hepatitis B virus is a useful model for studying the hepadenoviruses, of which human hepatitis B virus is the prototype. The utility of this model has been limited, however, by the difficulties associated with anesthetizing and obtaining liver biopsies from ducks. We developed a technique using Telazol (13 mg/kg) to anesthetize ducks before surgical biopsy of the liver in ducks infected with duck hepatitis B virus. Eight Pekin ducks infected with duck hepatitis B virus underwent serial biopsies at 4- to 5-week intervals. There was one perioperative death in 34 surgical procedures with no evidence on intra-abdominal sepsis or wound complications. Telazol can be used safely and humanely to anesthetized ducks without the need for general endotracheal anesthesia.
authors.affiliation: Department of Surgery, American Oncologic Hospital, Philadelphia, PA.
authors.forename: N Z
authors.initials: NZ
authors.lastname: Carp
authors.forename: J
authors.initials: J
authors.lastname: Saputelli
authors.forename: T C
authors.initials: TC
authors.lastname: Halbherr
authors.forename: W S
authors.initials: WS
authors.lastname: Mason
authors.forename: A R
authors.initials: AR
authors.lastname: Jilbert
mesh_terms: D000778:Anesthetics, Dissociative; D000818:Animals; D001706:Biopsy / Q000379:methods*; D004338:Drug Combinations; D004372:Ducks / Q000601:surgery*; D015611:Hepatitis B Virus, Duck; D006524:Hepatitis, Viral, Animal / Q000209:etiology / Q000473:pathology; D008099:Liver / Q000473:pathology*; D013992:Tiletamine; D015041:Zolazepam
chemical_list: D000778:Anesthetics, Dissociative; D004338:Drug Combinations; C006131:tiletamine, zolazepam drug combination; D013992:Tiletamine; D015041:Zolazepam