Relapsing hepatitis due to cytomegalovirus?
A case of agammaglobulinaemia with hyper IgM (the 'hyper-IgM syndrome') is described, in which a serological diagnosis of cytomegalovirus infection was made during repeated episodes of hepatitis. Three unrelated serological tests agreed with each other, but eventually it appeared that the reactions were non-specific. This shows the limitation of confirmation by tests which are used routinely.
Galama
J M
JM
Department of Virology, University of Nijmegen, The Netherlands.
van der Meer
J W
JW
van Munster
I
I
Weemaes
C R
CR
D000328:Adult; D000361:Agammaglobulinemia / Q000150:complications / Q000276:immunology; D000914:Antibodies, Viral / Q000032:analysis; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000276:immunology; D005260:Female; D006525:Hepatitis, Viral, Human / Q000382:microbiology*; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications / Q000276:immunology; D007118:Immunoassay; D007075:Immunoglobulin M / Q000032:analysis / Q000276:immunology; D012008:Recurrence; D013577:Syndrome
D000914:Antibodies, Viral; D007075:Immunoglobulin M