title: Antibody response to the immediate early protein of cytomegalovirus in renal transplant recipients.
abstract: The antibody response to the immediate early protein (IEP) of cytomegalovirus (CMV) was examined in seven renal transplant recipients during CMV reactivation and associated clinical abnormalities. Three cases with antibody increase to the IEP in the week after CMV isolation had no CMV-induced disease. The four patients without antibody increase exhibited laboratory abnormalities and three of them had renal dysfunction. In this small number of patients, the antibody response to the IEP in the week after isolation of CMV was associated with absence of abnormal clinical laboratory findings including renal function, and the prognosis was good for graft function in renal transplant recipients with CMV reactivation.
authors.affiliation: Department of Virology, Toyama Medical and Pharmaceutical University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Shiraki
authors.forename: M
authors.initials: M
authors.lastname: Ishibashi
authors.forename: T
authors.initials: T
authors.lastname: Okuno
authors.forename: K
authors.initials: K
authors.lastname: Yamanishi
authors.forename: M
authors.initials: M
authors.lastname: Takahashi
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: K
authors.initials: K
authors.lastname: Baba
authors.forename: H
authors.initials: H
authors.lastname: Yabuuchi
authors.forename: Y
authors.initials: Y
authors.lastname: Kokado
authors.forename: S
authors.initials: S
authors.lastname: Takahara
mesh_terms: D000914:Antibodies, Viral / Q000096:biosynthesis*; D000956:Antigens, Viral / Q000276:immunology*; D003587:Cytomegalovirus / Q000254:growth & development / Q000276:immunology* / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000276:immunology* / Q000382:microbiology; D006801:Humans; D017874:Immediate-Early Proteins; D016030:Kidney Transplantation / Q000276:immunology*; D014775:Virus Activation / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral; D017874:Immediate-Early Proteins; C044582:immediate-early proteins, cytomegalovirus