title: Human leucocyte antigens and tardive dyskinesia.
abstract: HLA status was assessed in matched groups of schizophrenics, 20 with and 20 without tardive dyskinesia. The antigen frequencies were also compared with that in a control sample. The anticipated excess of HLA-B44 was not confirmed. Pooled data displayed a shortfall of HLA-Cw7 and an excess of HLA-B44 in schizophrenics relative to population controls.
authors.affiliation: Royal Edinburgh Hospital.
authors.forename: K W
authors.initials: KW
authors.lastname: Brown
authors.forename: T
authors.initials: T
authors.lastname: White
mesh_terms: D000328:Adult; D000368:Aged; D014150:Antipsychotic Agents / Q000009:adverse effects; D004409:Dyskinesia, Drug-Induced / Q000209:etiology / Q000276:immunology*; D005260:Female; D005787:Gene Frequency; D005838:Genotype; D006680:HLA Antigens / Q000235:genetics / Q000276:immunology*; D015235:HLA-B Antigens / Q000235:genetics / Q000276:immunology; D059948:HLA-B44 Antigen; D015236:HLA-C Antigens / Q000235:genetics / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000188:drug therapy / Q000276:immunology*
chemical_list: D014150:Antipsychotic Agents; D006680:HLA Antigens; D015235:HLA-B Antigens; D059948:HLA-B44 Antigen; D015236:HLA-C Antigens; C040178:HLA-C*70 antigen