title: A mutation defining ultrainduction of the Escherichia coli gal operon.
abstract: Tn10 insertion in the galS (ultrainduction factor) gene of Escherichia coli allows the gal operon to be constitutively expressed at a very high level, equal to that seen in a delta galR strain in the presence of an inducer. The insertion has been mapped by criss-cross Hfr matings and by marker rescue into Kohara phages at 46 min on the E. coli chromosome.
authors.affiliation: Laboratory of Molecular Biology, National Cancer Institute, Bethesda, Maryland 20892.
authors.forename: A
authors.initials: A
authors.lastname: Golding
authors.forename: M J
authors.initials: MJ
authors.lastname: Weickert
authors.forename: J P
authors.initials: JP
authors.lastname: Tokeson
authors.forename: S
authors.initials: S
authors.lastname: Garges
authors.forename: S
authors.initials: S
authors.lastname: Adhya
mesh_terms: D004251:DNA Transposable Elements; D004926:Escherichia coli / Q000235:genetics*; D005690:Galactose / Q000235:genetics*; D015964:Gene Expression Regulation, Bacterial; D009154:Mutation; D009876:Operon; D012097:Repressor Proteins / Q000235:genetics
chemical_list: D004251:DNA Transposable Elements; D012097:Repressor Proteins; D005690:Galactose