A community-based feasibility study using wheat bran fiber supplementation to lower colon cancer risk.
METHODS
In this feasibility study, free-living older adults (n = 180; means = 67.5 years old) were randomly assigned to one of three levels of a 3-month standardized compliance enhancement program.


RESULTS
Regarding subject compliance with the 18 g/day wheat bran fiber supplement, the high compliance enhancement group had a superior regimen compliance rate (88%) versus the medium and low groups, (66 and 29%, respectively) (P = 0.01), with similar attrition rates.


CONCLUSIONS
No significant gastrointestinal side effects and changes in body weight were reported. For similar efficacy, the comprehensive compliance enhancement group had the greatest cost effectiveness.
Ho
E E
EE
Cancer Prevention and Control Program, Arizona Cancer Center, University of Arizona, Tucson 85724.
Atwood
J R
JR
Benedict
J
J
Ritenbaugh
C
C
Sheehan
E T
ET
Abrams
C
C
Alberts
D
D
Meyskens
F L
FL
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D003110:Colonic Neoplasms / Q000178:diet therapy / Q000517:prevention & control* / Q000523:psychology; D003153:Community Health Services / Q000191:economics / Q000458:organization & administration* / Q000592:standards; D003362:Cost-Benefit Analysis; D004043:Dietary Fiber / Q000008:administration & dosage*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D010353:Patient Education as Topic / Q000191:economics / Q000458:organization & administration* / Q000592:standards; D014908:Triticum