Treatment of experimental murine Coxsackie B3 myocarditis.
Using the murine model of coxsackievirus B3-induced myocarditis we studied the effects of various immunosuppressive agents on the course and outcome of the disease in genetically different strains of mice. The response to drug treatment varied greatly among the strains of inbred mice, which suggests different immune pathomechanisms operative in mediating myocarditis.
Herzum
M
M
Philipps University, Department of Internal Medicine-Cardiology, Marburg, Germany.
Huber
S A
SA
Weller
R
R
Grebe
R
R
Maisch
B
B
D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D003384:Coxsackievirus Infections / Q000628:therapy*; D016572:Cyclosporine / Q000627:therapeutic use; D029822:Enterovirus B, Human; D007165:Immunosuppression Therapy; D007694:Killer Cells, Natural; D008212:Lymphocyte Depletion; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D009205:Myocarditis / Q000382:microbiology* / Q000628:therapy*; D011241:Prednisone / Q000627:therapeutic use
D000911:Antibodies, Monoclonal; D016572:Cyclosporine; D011241:Prednisone