Dose to red bone marrow from natural radon and thoron exposure.
The age-dependent radiation dose to the haematopoietic tissue of bone marrow has been calculated for exposure to radon, thoron and their daughter products. The component of dose due to pure radon is dependent on the fat content of the marrow, since the solubility of radon in fat is about 16 times that in tissue. The mean dose equivalent muSv to the total active marrow is estimated for a range of fat cell diameters from 25 to 200 microns, taking account of the percentage cellularity and distribution of active marrow as a function of age. Similarly, the dose due to the inhalation of short-lived radon daughters was estimated, based on measurements in blood and marrow, modified to allow for the greater deposition of daughter products expected in children. An estimate of the age-dependent dose from long-lived radon daughters was made from uranium miner and natural exposure data. Dose estimates were made for the average UK indoor exposure to radon gas of 20 Bq/m3 and an equilibrium equivalent thoron concentration of 0.3 Bq/m3. The annual radon and thoron derived dose to the active marrow of the newborn was calculated as 30 and 40 muSv, respectively. For a 10-year-old child, the radon and thoron derived annual dose are 70 and 40 muSv, and for a 40-year-old adult 90 and 30 muSv, respectively. The above values exhibit wide range limits due principally to uncertainties in the accumulation of 210Pb in bone, and 210Po in marrow. These data indicate that at the average UK exposure, the alpha-particle dose to active marrow is dominated by that derived from inhaled radon and thoron compared with dietary intake. In infants the dose is dominated by thoron daughters. At the UK radon Action Limit of 200 Bq/m3, the radon and associated thoron derived dose is similar to that from all low LET sources. This work shows that the dose to red bone marrow from radon and thoron is significant, and that the possibility of leukaemia induced by these radiation sources warrants further investigation.
Richardson
R B
RB
H. H. Wills Physics Laboratory, University of Bristol, UK.
Eatough
J P
JP
Henshaw
D L
DL
D000273:Adipose Tissue / Q000528:radiation effects; D000293:Adolescent; D000328:Adult; D000368:Aged; D000396:Air Pollutants, Radioactive / Q000032:analysis; D001729:Bismuth; D001853:Bone Marrow / Q000528:radiation effects*; D002648:Child; D002675:Child, Preschool; D004781:Environmental Exposure; D005260:Female; D006207:Half-Life; D006412:Hematopoietic Stem Cells / Q000528:radiation effects; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007854:Lead; D008297:Male; D008433:Mathematics; D008875:Middle Aged; D008954:Models, Biological; D011059:Polonium; D011829:Radiation Dosage; D011851:Radioactivity; D011886:Radon; D017687:Radon Daughters
D000396:Air Pollutants, Radioactive; D017687:Radon Daughters; D007854:Lead; D011059:Polonium; D011886:Radon; D001729:Bismuth