More insights into the complex physiology of TNF.
Tumor necrosis factor (TNF), a multifactorial cytokine involved in a plethora of cell regulatory and differentiative processes, was the subject of a recent conference. It is perhaps best known as a major player in the pathophysiology of numerous diseases but TNF clearly has many beneficial effects and is considered to be a promising therapeutic agent.
Chouaib
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Laboratoire d'Immunologie UA 1156, Villejuif, France.
Branellec
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Buurman
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D000818:Animals; D016207:Cytokines / Q000502:physiology; D004341:Drug Evaluation; D006801:Humans; D011956:Receptors, Cell Surface / Q000502:physiology; D018124:Receptors, Tumor Necrosis Factor; D011994:Recombinant Proteins / Q000627:therapeutic use; D014409:Tumor Necrosis Factor-alpha / Q000502:physiology* / Q000627:therapeutic use
D016207:Cytokines; D011956:Receptors, Cell Surface; D018124:Receptors, Tumor Necrosis Factor; D011994:Recombinant Proteins; D014409:Tumor Necrosis Factor-alpha