title: Intermittent interpleural injection of bupivacaine and methylprednisolone for analgesia in metastatic thoracic neoplasm.
abstract: Three patients with intractable chest wall pain due to diffusely metastatic thoracic neoplasm were successfully treated with intermittent interpleural steroid injections. Intermittent administration of 0.5% bupivacaine mixed with methylprednisolone suspension (Depo-Medrol) was effective in controlling intractable pain due to metastatic cancer. Pain relief with this technique lasted for periods in excess of 3 weeks between injections. Intermittent interpleural block may be a useful addition to the therapeutic armamentarium in dealing with chronic pain due to metastatic neoplasm.
authors.affiliation: Ohio State University, Columbus.
authors.forename: D S
authors.initials: DS
authors.lastname: Klein
authors.forename: P W
authors.initials: PW
authors.lastname: Klein
mesh_terms: D001943:Breast Neoplasms / Q000150:complications; D002045:Bupivacaine / Q000008:administration & dosage / Q000627:therapeutic use*; D018288:Carcinoma, Small Cell / Q000150:complications; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D013899:Thoracic Neoplasms / Q000150:complications*
chemical_list: D008775:Methylprednisolone; D002045:Bupivacaine