[Pain and painkillers. 1. Neurophysiologic component].
A pain impulse is transmitted in the thin nerves from nerve cell to nerve cell, by means of neurotransmitters and -modulators, shed in the synapses. In the dorsal horn of the spinal medulla the impulse is either or not allowed to travel to the brain by a 'gate control' mechanism, and pain may be felt. The gate is influenced by cells in the nearby situated substantia gelatinosa, thick nerves and efferent nerves from higher situated centra.
Schuurs
A H
AH
Academisch Centrum Tandheelkunde Amsterdam (ACTA).
Baart
J A
JA
Duyx
M P
MP
D000700:Analgesics; D006801:Humans; D010146:Pain / Q000188:drug therapy / Q000503:physiopathology*; D009435:Synaptic Transmission
D000700:Analgesics
Pijn en pijnstiller. I. Neurofysiologische component.