[Initial results of the Project of the German Breast Cancer Study Group on "Breast saving therapy of the small breast cancer"].
In the German Breast Cancer Study Group (GBSG) multicenter trial "Breast preservation in small breast cancer" 1119 patients were accrued over a period of six years. The study was originally designed as a randomized trial which had to be changed into a prospective observation study. A high therapeutic standard was guaranteed by quality control. The univariate analysis of prognostic variables was the first step to a valid treatment comparison. Those factors determined as being significant were combined with the treatment effects in a multivariate analysis. The published results were obtained after a median observation time of four years.
Rauschecker
H F
HF
Chirurgische Universitätsklinik Göttingen.
Gatzemeier
W
W
Sauer
R
R
Seegenschmiedt
M H
MH
Schauer
A
A
Ummenhofer
L
L
Sauerbrei
W
W
Schmoor
C
C
Schumacher
M
M
D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D015412:Mastectomy, Segmental / Q000379:methods*; D008875:Middle Aged; D009367:Neoplasm Staging; D009376:Neoplasms, Hormone-Dependent / Q000401:mortality / Q000473:pathology / Q000601:surgery; D011446:Prospective Studies; D011879:Radiotherapy Dosage; D011960:Receptors, Estrogen / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis; D015996:Survival Rate
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone
Erste Ergebnisse des Projekts der Deutschen Brustkrebs-Studiengruppe (GBSG) zur "Brusterhaltenden Therapie des kleinen Mammacarcinoms".