The surgical management of familial adenomatous polyposis in Northern Ireland.
Sixty-eight patients from 18 families have been identified as having familial adenomatous polyposis during the past 30 years in Northern Ireland (population 1.5 million). Six of the 18 probands (33%) had developed colonic carcinoma when first seen at mean age 34 years. Ten of the 44 patients identified by surgical screening (21%) at a significantly lower mean age of 23 years had colonic carcinoma. Surgical management has generally been by subtotal colectomy with ileorectal anastomosis, or by panproctocolectomy and ileostomy.
Campbell
W J
WJ
Department of Surgery, Queen's University of Belfast, Belfast City Hospital.
Irwin
S T
ST
Parks
T G
TG
D011125:Adenomatous Polyposis Coli / Q000150:complications / Q000453:epidemiology / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D002648:Child; D003110:Colonic Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000601:surgery*; D006801:Humans; D015994:Incidence; D008403:Mass Screening; D008875:Middle Aged; D009660:Northern Ireland / Q000453:epidemiology; D012086:Reoperation / Q000706:statistics & numerical data