Preoptic-brainstem connections and maternal behavior in rats.
This study presents evidence supporting the view that preoptic area (POA) projections through the ventral tegmental area (VTA) to lower brainstem regions are important for maternal behavior in postpartum rats. Experiment 1 demonstrated that bilateral coronal knife cuts posterior to the VTA disrupted maternal behavior, and Experiment 2 demonstrated a similar disruption when a unilateral knife cut that severed the lateral connections of the medial POA was paired with a contralateral knife cut posterior to the VTA. In a final anatomical experiment using horseradish peroxidase histochemistry, it was shown that knife cuts posterior to the VTA do sever POA efferents. However, such cuts severed other ascending and descending pathways as well, and these may also be involved in maternal behavior control.
Numan
M
M
Department of Psychology, Boston College, Chestnut Hill, Massachusetts 02167.
Numan
M J
MJ
D000818:Animals; D001931:Brain Mapping; D001933:Brain Stem / Q000502:physiology*; D004525:Efferent Pathways / Q000502:physiology; D005260:Female; D007774:Lactation / Q000502:physiology; D008425:Maternal Behavior; D009412:Nerve Fibers / Q000502:physiology; D009425:Nesting Behavior / Q000502:physiology; D009474:Neurons / Q000502:physiology; D011301:Preoptic Area / Q000502:physiology*; D051381:Rats; D009435:Synaptic Transmission / Q000502:physiology*; D013681:Tegmentum Mesencephali / Q000502:physiology