title: [Effect of selenium on the connective tissue metabolism in rats].
abstract: Rats were chronically exposed to poisonous sodium selenite in concentrations 0.5 mg/kg b. m. for 10 weeks. As a result, hydroxyproline contents in blood serum increased, as well as its excretion with urine. It was proved that the procedure enhanced urinary glycosaminoglycane excretion and increased the contents of the protein-related glycosaminoglycanes in the serum. This was accompanied by increased quantities of keratane sulphate and heparin sulphate. The results confirmed that selenium poisonings influenced connective tissues.
authors.forename: E I
authors.initials: EI
authors.lastname: Kucharz
authors.forename: K
authors.initials: K
authors.lastname: Olczyk
authors.forename: P
authors.initials: P
authors.lastname: Sonecki
mesh_terms: D000818:Animals; D002908:Chronic Disease; D003238:Connective Tissue / Q000187:drug effects* / Q000378:metabolism; D004195:Disease Models, Animal; D006025:Glycosaminoglycans / Q000378:metabolism*; D006909:Hydroxyproline / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012643:Selenium / Q000506:poisoning*; D018038:Sodium Selenite; D013997:Time Factors; D014874:Water Pollutants, Chemical / Q000506:poisoning*
chemical_list: D006025:Glycosaminoglycans; D014874:Water Pollutants, Chemical; D012643:Selenium; D018038:Sodium Selenite; D006909:Hydroxyproline
vernacular_title: Vliianie selena na metabolizm soedinitel'noĭ tkani u krys.