Demonstration of a haemopoietic pluripotent stem cell adhesion molecule (HPSC-CAM) in mouse bone marrow.
In this paper the probable mechanism of the haemopoietic pluripotent stem cell (PSC) homing into the bone-marrow is investigated. Experiments were done to understand the role of fibronectin hexapeptide and ubiquitin. Attempts to isolate the PSC adherence molecule were made. A new adherence assay for PSC has been described.
Desai
S S
SS
Cell Biology Division, Tata Memorial Centre, Bombay, India.
Kale
S A
SA
Rao
S G
SG
D000818:Animals; D000906:Antibodies / Q000276:immunology; D001853:Bone Marrow / Q000737:chemistry*; D002448:Cell Adhesion / Q000187:drug effects; D015815:Cell Adhesion Molecules / Q000737:chemistry* / Q000302:isolation & purification; D002478:Cells, Cultured / Q000187:drug effects; D003114:Colony-Forming Units Assay; D005260:Female; D005353:Fibronectins / Q000494:pharmacology*; D006412:Hematopoietic Stem Cells / Q000737:chemistry* / Q000378:metabolism; D008099:Liver / Q000196:embryology / Q000378:metabolism; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D014452:Ubiquitins / Q000276:immunology
D000906:Antibodies; D015815:Cell Adhesion Molecules; D005353:Fibronectins; D014452:Ubiquitins