title: Identification of human papillomavirus antigen in a bladder tumor.
abstract: Human papillomavirus (HPV) antigen was found in one of six noninfiltrating (grade II) carcinomas of the bladder. The antigen was located in the nuclei of the superficial cells. This virus-bearing tumor occurred in a patient with no known risk factors. The presence of HPV in low-grade urinary lesions seems to be frequent and may reflect the early stages of carcinogenesis; in fact, HPV infections may cause papillomas and carcinomas of the urothelial mucosae as well as the genital mucosae.
authors.affiliation: Department of Histology and Embryology, Charles Nicolle Hospital, University and Regional Medical Center, Rouen, France.
authors.forename: F
authors.initials: F
authors.lastname: Roussel
authors.forename: J M
authors.initials: JM
authors.lastname: Picquenot
authors.forename: O
authors.initials: O
authors.lastname: Rousseau
mesh_terms: D000956:Antigens, Viral / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010212:Papilloma / Q000382:microbiology* / Q000473:pathology; D027383:Papillomaviridae / Q000302:isolation & purification*; D001749:Urinary Bladder Neoplasms / Q000382:microbiology* / Q000473:pathology
chemical_list: D000956:Antigens, Viral