[Preliminary study of the prevalence of Helicobacter pylori in Tananarive, Madagascar and the antibacterial activity in vitro of 13 Malagasy medicinal plants on this germ].
Helicobacter pylori infection has been studied in 60 patients who were suffering from either a peptic ulcer disease or a gastritis complaint. Helicobacter pylori was searched in antral biopsy specimens using standard bacteriological methods (Gram-staining urea-test, culture) and histological staining techniques (hematoxylin-eosin-saffron, undifferentiated Giemsa). The culture was successful in 40 cases. The antibacterial activity of 13 malagasy medicinal plants has been tested versus Helicobacter pylori using disc method on agar culture. For five extracts, we observed an anti-Helicobacter pylori activity which would deserve further investigations.
Cassel-Beraud
A M
AM
Institut Pasteur de Madagascar, Antananarivo.
Le Jan
J
J
Mouden
J C
JC
Andriantsoa
M
M
Andriantsiferana
R
R
D000328:Adult; D001706:Biopsy; D005260:Female; D005756:Gastritis / Q000175:diagnosis / Q000382:microbiology* / Q000473:pathology; D005773:Gastroscopy; D016481:Helicobacter Infections / Q000150:complications* / Q000453:epidemiology*; D016480:Helicobacter pylori; D006801:Humans; D008270:Madagascar / Q000453:epidemiology; D008297:Male; D016488:Medicine, African Traditional; D008826:Microbial Sensitivity Tests; D010437:Peptic Ulcer / Q000175:diagnosis / Q000382:microbiology* / Q000473:pathology; D010946:Plants, Medicinal; D011159:Population Surveillance; D015995:Prevalence
Etude préliminaire de la prévalence d'Helicobacter pylori à Tananarive, Madagascar et de l'activité anti-bactérienne in vitro sur ce germe de 13 plantes médicinales malgaches.