Receptor synthesis and routing to the plasma membrane.
Hormones and other extracellular proteins exert their effects on the cells that they influence by interacting with receptors in the plasma membranes of these target cells. For these interactions to occur, the receptor proteins must be efficiently synthesized, processed, and transported to the plasma membrane. This review summarizes the events and organelles involved in this process.
Brumley
L M
LM
Department of Cell Biology, University of Alabama, Birmingham 35294-0005.
Marchase
R B
RB
D000818:Animals; D001692:Biological Transport; D002462:Cell Membrane / Q000378:metabolism; D004721:Endoplasmic Reticulum / Q000378:metabolism; D006056:Golgi Apparatus / Q000378:metabolism; D006801:Humans; D007425:Intracellular Membranes / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism*; D014176:Protein Biosynthesis; D011956:Receptors, Cell Surface / Q000378:metabolism*
D008565:Membrane Proteins; D011956:Receptors, Cell Surface