Effect of cyclosporin A on trichinosis. A histochemical study.
The aim of this work was to reveal the possible effect of the drug CSA treatment in experimental trichinosis on some important tissue enzymes; alklline and acid phosphatases, succinic dehydrogenase and alpha-esterase. This study revealed that the effect of the drug was apparently evident on succinic dehydrogenase enzyme which returns back to the control. The diminished acid phosphatase activity showed the effect of the drug on the T-cells.
Boulos
L M
LM
Departments of Parasitology, Faculty of Medicine Alexandria University, Egypt.
Abou-Samra
L M
LM
el-Mansoury
S T
ST
Kelda
I P
IP
D000818:Animals; D016572:Cyclosporine / Q000627:therapeutic use*; D004950:Esterases / Q000032:analysis; D006651:Histocytochemistry; D051379:Mice; D009132:Muscles / Q000201:enzymology* / Q000469:parasitology; D010744:Phosphoric Monoester Hydrolases / Q000032:analysis; D013385:Succinate Dehydrogenase / Q000032:analysis; D014235:Trichinellosis / Q000188:drug therapy*
D016572:Cyclosporine; D013385:Succinate Dehydrogenase; D004950:Esterases; D010744:Phosphoric Monoester Hydrolases