title: High-fiber diet reduces serum estrogen concentrations in premenopausal women.
abstract: The effect of dietary fiber on serum estrogen concentrations was studied in 62 premenopausal women. Their estimated daily dietary fiber intake was increased from an average of approximately 15 g to 30 g/d by supplementation with wheat, oat, or corn bran. This was done without any significant decrease in dietary fat consumption. After 2 mo on the high-fiber diets, the wheat-bran-supplemented group showed significant reductions in serum estrone (P less than 0.002) and estradiol (P less than 0.02) but no change in serum progesterone or sex-hormone-binding globulin concentrations. The serum estrogens were unaffected by dietary-fiber supplementation with oat or corn brans.
authors.affiliation: Division of Nutrition and Endocrinology, American Health Foundation, Valhalla, NY 10595.
authors.forename: D P
authors.initials: DP
authors.lastname: Rose
authors.forename: M
authors.initials: M
authors.lastname: Goldman
authors.forename: J M
authors.initials: JM
authors.lastname: Connolly
authors.forename: L E
authors.initials: LE
authors.lastname: Strong
mesh_terms: D000328:Adult; D004041:Dietary Fats / Q000494:pharmacology; D004043:Dietary Fiber / Q000494:pharmacology*; D002523:Edible Grain; D004967:Estrogens / Q000097:blood*; D004970:Estrone / Q000097:blood; D005260:Female; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D009994:Osmolar Concentration; D012738:Sex Hormone-Binding Globulin / Q000032:analysis; D014908:Triticum; D003313:Zea mays
chemical_list: D004041:Dietary Fats; D004043:Dietary Fiber; D004967:Estrogens; D012738:Sex Hormone-Binding Globulin; D004970:Estrone