title: Biological and molecular comparisons of human (HM-175) and simian (AGM-27) hepatitis A viruses.
abstract: Comparisons of HM-175, the prototype human strain of hepatitis A virus, and AGM-27, a simian isolate, indicate that the two HAV viruses differ substantially in sequence and in biological characteristics. The extent of the differences suggests that hepatitis A viruses have a greater potential for diversity than previously assumed.
authors.affiliation: Hepatitis Viruses Section, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.
authors.forename: S U
authors.initials: SU
authors.lastname: Emerson
authors.forename: S A
authors.initials: SA
authors.lastname: Tsarev
authors.forename: R H
authors.initials: RH
authors.lastname: Purcell
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002213:Capsid / Q000235:genetics; D000882:Haplorhini; D006507:Hepatovirus / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D006801:Humans