Regional mapping of the parathyroid hormone gene (PTH) by cytogenetic and molecular studies.
The locus for the human parathyroid hormone gene (PTH) was assigned to a region proximal to 11p15.4 using restriction fragment length polymorphisms and gene dose studies performed on a patient with the Beckwith-Wiedemann syndrome accompanied with a chromosome abnormality [46,XX,-14,+der(14),t(14;11)(q32.3;p15.3)pat]. Our data suggest that PTH is localized in 11p15.3----p15.1, most likely near the border of the bands 11p15.4 and 11p15.3.
Tonoki
H
H
Department of Pediatrics, Hokkaido University School of Medicine, Sapporo, Japan.
Narahara
K
K
Matsumoto
T
T
Niikawa
N
N
D001506:Beckwith-Wiedemann Syndrome / Q000235:genetics; D015139:Blotting, Southern; D002869:Chromosome Aberrations; D002874:Chromosome Mapping; D002880:Chromosomes, Human, Pair 11; D005260:Female; D006801:Humans; D007223:Infant; D007621:Karyotyping; D008297:Male; D010281:Parathyroid Hormone / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length
D010281:Parathyroid Hormone