title: Attachment of cementum on different hydroxylapatite ceramic (HAC) substrata in vivo. A light and electron microscopic study.
abstract: The role of substrate surface characteristics for periodontal regeneration was studied in rats. Cementogenesis was initiated by dental follicle cells retained after dissecting out a molar tooth germ in 5-day-old rats. The tooth germ was substituted by a bone replacement material, namely HAC granules of porous consistency. Tissue blocks were removed after 24 weeks and processed for light and electron microscopic examination. On all HAC surfaces a new cementum-like tissue developed, similar to that of natural root surfaces. The results strongly indicate that the exposure of collagen fibers is not essential in order to achieve new periodontal attachment.
authors.affiliation: Department of orthodontics, Free University of Berlin, FRG.
authors.forename: E A
authors.initials: EA
authors.lastname: Holtgrave
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D003739:Dental Cementum / Q000502:physiology* / Q000648:ultrastructure; D017886:Durapatite; D004846:Epithelial Attachment / Q000502:physiology / Q000648:ultrastructure; D006882:Hydroxyapatites / Q000737:chemistry*; D010519:Periodontium / Q000502:physiology* / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains; D013499:Surface Properties; D014083:Tooth Germ / Q000502:physiology
chemical_list: D001672:Biocompatible Materials; D006882:Hydroxyapatites; D017886:Durapatite