title: [Observations in vivo on spermicidal effect of nonoxynol-9 contraceptive in forms of effervescent suppository and film].
abstract: Spermicidal effect of nonoxynol-9 contraceptive in forms of efferscent suppository and film trade in China were studied in vivo. There were noticeable differences on the spermicidal effect in vivo between the two types and different doses. This study indicated that nonoxynol-9 efferscent suppository was more effective than the np-9 film in spermicidal efficacy. (1) No live sperm was found in the samples of vaginal and cervical mucus in the 20 cases of the suppository group. (2) There were live sperms in the samples of vaginal mucus of 6 cases and cervical mucus of 3 cases among the 20 cases of the film group.
authors.affiliation: Tianjin Municipal Research Institute for Family planning.
authors.forename: Y Z
authors.initials: YZ
authors.lastname: Hu
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D017137:Nonoxynol; D010570:Pessaries; D011092:Polyethylene Glycols / Q000008:administration & dosage / Q000494:pharmacology*; D013089:Spermatocidal Agents / Q000008:administration & dosage / Q000494:pharmacology*; D013094:Spermatozoa / Q000187:drug effects*
chemical_list: D013089:Spermatocidal Agents; D017137:Nonoxynol; D011092:Polyethylene Glycols