[The influence of post-operative chemotherapy courses on the prognosis of small cell lung cancer treated with chemotherapy and surgery].
A group of 110 cases of SCLC treated with chemotherapy (CT) and surgery, their 5-yr survival rate was 28.9%. Different 5-yr survival rates were seen in the patients with one to more than 4 courses of post-operative CT, there were 17.7%, 27.3%, 31.3% and 53.7% respectively. The 5-yr survival rate of the patients with 3 or 4 CT courses was better than those patients with only one or two CT courses, P less than 0.05, especially meaningful in the patients treated with CT-surgery-CT, their 5-yr survival rates were 8.3%, 40%, 66.7% and 62.6% respectively, among which group, 11 cases refused to receive post-operative CT died within one year and one month. It was suggested that post-operative CT was very important to the long survival rate of SCLC treated with CT and surgery, 3 and more than four courses of post-operative CT were optimal.
Liao
M L
ML
Shanghai Chest Hospital.
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D018288:Carcinoma, Small Cell / Q000188:drug therapy* / Q000401:mortality / Q000601:surgery; D003131:Combined Modality Therapy; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000601:surgery; D011446:Prospective Studies; D015996:Survival Rate
D000970:Antineoplastic Agents