title: The effect of ammonium chloride and sodium bicarbonate ingestion on the physical working capacity at the fatigue threshold.
abstract: The purpose of this investigation was to examine the effect of ammonium chloride (NH4Cl) and sodium bicarbonate (NaHCO3) ingestion on the physical working capacity at the fatigue threshold (PWCFT). Eighteen adult males (mean age, SD = 23, 2 years) volunteered for two experiments (experiment 1, n = 9; experiment 2, n = 9). In both experiments, the subjects orally ingested 0.3 g.kg-1 body weight of NH4Cl and NaHCO3 over a 3-h period in random order on days separated by 72 h or more. In experiment 1, following ingestion of the substance, the subjects performed a discontinuous incremental cycle ergometer test to the onset of PWCFT which was estimated from integrated electromyography voltages at the vastus lateralis muscle. In experiment 2, the subjects performed a continuous PWCFT test. The results of these experiments indicated that NH4Cl and NaHCO3 ingestion had no significant (P greater than 0.05) effect on PWCFT (experiment 1: NH4Cl = 257, SD 26 W; NaHCO3 = 256, SD 22 W; t = 0.06; r = 0.866; experiment 2: NH4Cl = 231, 14 W; NaHCO3 = 216, 16 W; t = 1.78; r = 0.857).
authors.affiliation: Center for Youth Fitness and Sports Research, University of Nebraska-Lincoln 68588-0229.
authors.forename: T J
authors.initials: TJ
authors.lastname: Housh
authors.forename: H A
authors.initials: HA
authors.lastname: deVries
authors.forename: G O
authors.initials: GO
authors.lastname: Johnson
authors.forename: S A
authors.initials: SA
authors.lastname: Evans
authors.forename: S
authors.initials: S
authors.lastname: McDowell
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000643:Ammonium Chloride / Q000494:pharmacology*; D001639:Bicarbonates / Q000494:pharmacology*; D004056:Differential Threshold; D004576:Electromyography; D006801:Humans; D008297:Male; D010807:Physical Endurance / Q000187:drug effects*; D012964:Sodium / Q000494:pharmacology*; D017693:Sodium Bicarbonate
chemical_list: D001639:Bicarbonates; D000643:Ammonium Chloride; D017693:Sodium Bicarbonate; D012964:Sodium