title: Lessons from caprine and ovine retrovirus infections.
abstract: Two lentiviruses that infect sheep and goats have been shown to be closely related to the human immunodeficiency virus (HIV). These ungulate lentiviruses cause a spectrum of diseases, including arthritis in their natural hosts. The molecular and cellular biology of these viruses as well as possible pathogenic mechanisms is compared to HIV-1 in order to identify common features and significant differences between the human and animals pathogens.
authors.affiliation: Laboratory of Tumor Cell Biology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland.
authors.forename: F H
authors.initials: FH
authors.lastname: Michaels
authors.forename: K L
authors.initials: KL
authors.lastname: Banks
authors.forename: M S
authors.initials: MS
authors.lastname: Reitz
mesh_terms: D000818:Animals; D016088:Arthritis-Encephalitis Virus, Caprine / Q000302:isolation & purification; D006041:Goats; D016180:Lentivirus Infections / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D012192:Retroviridae Infections / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D012756:Sheep; D012757:Sheep Diseases / Q000209:etiology / Q000473:pathology*; D014790:Visna-maedi virus / Q000302:isolation & purification