Molecular models for recognition and activation at the benzodiazepine receptor: a review.
In this minireview an overview description of the different pharmacophores that have been proposed for the benzodiazepine receptor is presented. The methodology as well as the experimental information used in the development of each model will be described. Finally, the new experimental discoveries that are likely to affect the models presented are briefly indicated.
Villar
H O
HO
Molecular Research Institute, Palo Alto, CA 94304.
Davies
M F
MF
Loew
G H
GH
Maguire
P A
PA
D000818:Animals; D014151:Anti-Anxiety Agents / Q000737:chemistry / Q000378:metabolism*; D001569:Benzodiazepines; D008958:Models, Molecular; D015394:Molecular Structure; D011963:Receptors, GABA-A / Q000378:metabolism*
D014151:Anti-Anxiety Agents; D011963:Receptors, GABA-A; D001569:Benzodiazepines