[The effect of the different CSF components in convalescent animals on the recovery from a motor deficit in recipients with a homotopic brain lesion].
The effect of the CSF components of the rats who had restored motor deficiency after left unilateral removal of motor neocortex, was studied in the rats with an analogous brain lesion. The first group of animals received a thermostable fraction of the donor CSF containing active factors of the posture asymmetry (FPA). The second group of animals were given a high-molecular fraction of the donor CSF with active factors inactivating the FPA. The first group revealed a significant acceleration of compensatory processes. Only a temporary positive effect was observed in the second group. The findings can be used in neurological clinics when treating motor disorders of central genesis.
Danilovskiĭ
M A
MA
Loseva
I V
IV
Vartanian
G A
GA
D000818:Animals; D001704:Biopolymers; D001930:Brain Injuries / Q000134:cerebrospinal fluid* / Q000188:drug therapy / Q000503:physiopathology; D002555:Cerebrospinal Fluid / Q000502:physiology*; D002556:Cerebrospinal Fluid Proteins / Q000302:isolation & purification / Q000627:therapeutic use; D003289:Convalescence; D004292:Dominance, Cerebral / Q000187:drug effects / Q000502:physiology; D004353:Drug Evaluation, Preclinical; D008297:Male; D008970:Molecular Weight; D009044:Motor Cortex / Q000293:injuries; D009069:Movement Disorders / Q000134:cerebrospinal fluid* / Q000188:drug therapy / Q000503:physiopathology; D011187:Posture / Q000502:physiology; D051381:Rats
D001704:Biopolymers; D002556:Cerebrospinal Fluid Proteins
Vliianie razlichnykh komponentov likvora zhivotnykh-rekonvalistsentov na vosstanovlenie dvigatel'nogo defitsita u retsipientov s gomotopicheskim povrezhdeniem mozga.