title: Quantitative analysis of the Epstein-Barr virus-inducing properties of short-chain fatty acids present in the culture fluids of oral bacteria.
abstract: The culture fluids of various anaerobic bacteria induced the synthesis of early antigens (EA) in Epstein-Barr virus (EBV) carrying lymphoblastoid cells. The culture fluids of Corynebacterium butyricum and Fusobacterium nucleatum were the effective inducer on EA. The inducing activity was, to some extent, dependent on their n-butyric acid content, but appeared to be regulated by yet unidentified materials.
authors.affiliation: Department of Oral Microbiology, School of Dentistry, Asahi University, Gifu, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Asai
authors.forename: Y
authors.initials: Y
authors.lastname: Nakamura
authors.forename: M
authors.initials: M
authors.lastname: Yamamura
authors.forename: H
authors.initials: H
authors.lastname: Ikezawa
authors.forename: I
authors.initials: I
authors.lastname: Namikawa
mesh_terms: D000956:Antigens, Viral / Q000096:biosynthesis; D002087:Butyrates / Q000378:metabolism; D020148:Butyric Acid; D003352:Corynebacterium / Q000378:metabolism*; D005227:Fatty Acids / Q000378:metabolism*; D005673:Fusobacterium / Q000378:metabolism*; D004854:Herpesvirus 4, Human / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D009055:Mouth / Q000382:microbiology; D014407:Tumor Cells, Cultured; D014775:Virus Activation
chemical_list: D000956:Antigens, Viral; D002087:Butyrates; C033305:Epstein-Barr virus early antigen; D005227:Fatty Acids; D020148:Butyric Acid