title: Necrotizing bronchial aspergillosis in a patient receiving neoadjuvant chemotherapy for non-small cell lung carcinoma.
abstract: We describe a case of necrotizing bronchial aspergillosis which developed after lobectomy following neoadjuvant chemotherapy in a 73-year-old woman with non-small cell lung cancer. The lesion was visualized and biopsied through FBS, which played a useful role for early diagnosis of this disease. Itraconazole therapy was effective and safe.
authors.affiliation: Department of Thoracic Surgery, National Chubu Hospital, Aichi, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Niimi
authors.forename: M
authors.initials: M
authors.lastname: Kajita
authors.forename: H
authors.initials: H
authors.lastname: Saito
mesh_terms: D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001228:Aspergillosis / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D001232:Aspergillus fumigatus; D001980:Bronchi / Q000473:pathology; D001982:Bronchial Diseases / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications / Q000188:drug therapy*; D002945:Cisplatin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D017964:Itraconazole; D007654:Ketoconazole / Q000031:analogs & derivatives / Q000627:therapeutic use; D008175:Lung Neoplasms / Q000150:complications / Q000188:drug therapy*; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage; D009336:Necrosis; D014751:Vindesine / Q000008:administration & dosage
chemical_list: D000935:Antifungal Agents; D008937:Mitomycins; D017964:Itraconazole; D016685:Mitomycin; D002945:Cisplatin; D007654:Ketoconazole; D014751:Vindesine