title: [Oropharyngeal dysphagia due to a primary change in the pharyngeal musculature. A manometric and isotopic study].
abstract: Twenty-five patients with oropharyngeal dysphagia due to a variety of disorders (4 with muscular dystrophy, 4 with myasthenia gravis and 13 with inflammatory myopathies) were studied clinically by esophageal manometry and isotopic clearance. Clinically patients had moderate dysphagia and 45% other symptoms such as nasal regurgitation, bronchial aspiration, etc. The most important manometric abnormality was the feeble contractions of the pharyngeal musculature, more pronounced in patients with severe dysphagia (grade II). Isotopic clearance of the oropharynx showed slowing of the pharyngeal emptying curve and an increased residual activity in this area. Isotopic oropharyngeal clearance is a useful, comfortable and noninvasive test for determining the clinical improvement which accompanies the manometric recovery of the pharyngeal muscular contraction.
authors.affiliation: Hospital Clínico Universitario, Unidad de Motilidad Digestiva, Valencia.
authors.forename: R
authors.initials: R
authors.lastname: Añón
authors.forename: P
authors.initials: P
authors.lastname: Ibor
authors.forename: M
authors.initials: M
authors.lastname: Tomas-Ridocci
authors.forename: M
authors.initials: M
authors.lastname: Mínguez
authors.forename: F
authors.initials: F
authors.lastname: Mora
authors.forename: A
authors.initials: A
authors.lastname: Benages
authors.forename: E
authors.initials: E
authors.lastname: Moreno-Osset
authors.forename: B
authors.initials: B
authors.lastname: Calvo
mesh_terms: D003680:Deglutition Disorders / Q000145:classification / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008365:Manometry / Q000379:methods; D009960:Oropharynx / Q000000981:diagnostic imaging / Q000503:physiopathology; D010609:Pharyngeal Muscles / Q000000981:diagnostic imaging / Q000503:physiopathology*; D011877:Radionuclide Imaging; D013670:Sodium Pertechnetate Tc 99m
chemical_list: D013670:Sodium Pertechnetate Tc 99m
vernacular_title: Disfagia orofaríngea por alteración primaria de la musculatura faríngea. Estudio manométrico e isotópico.