title: [The effect of whole-body controlled hyperthermia on the energy resources of cancer patients].
abstract: The results of examination of 120 patients with advanced malignant melanoma, soft tissue sarcomas and lung and renal cancer suggest disturbance in mechanisms of energy supply during whole-body guided hyperthermia. Cell glucose uptake was inhibited in hyperglycemic patients. High energy loss in due to utilization of such alternative substrates as lipids and proteins which, in turn, potentiates peroxidation of lipids toxic to cell membranes. These data provide biochemical rationale for developing procedures aimed at managing biochemical dysbalance, increase in carbohydrate utilization included.
authors.forename: V I
authors.initials: VI
authors.lastname: Prokhorova
authors.forename: E A
authors.initials: EA
authors.lastname: Zhavrid
authors.forename: S Z
authors.initials: SZ
authors.lastname: Fradkin
authors.forename: V Z
authors.initials: VZ
authors.lastname: Rubanova
authors.forename: S V
authors.initials: SV
authors.lastname: Lappo
authors.forename: T P
authors.initials: TP
authors.lastname: Tsyrus'
mesh_terms: D000975:Antioxidants; D001786:Blood Glucose / Q000032:analysis; D004734:Energy Metabolism; D005947:Glucose / Q000008:administration & dosage; D006801:Humans; D006979:Hyperthermia, Induced; D007680:Kidney Neoplasms / Q000097:blood / Q000628:therapy*; D015227:Lipid Peroxidation; D008175:Lung Neoplasms / Q000097:blood / Q000628:therapy*; D008545:Melanoma / Q000097:blood / Q000628:therapy*; D012983:Soft Tissue Neoplasms / Q000097:blood / Q000628:therapy*; D013997:Time Factors
chemical_list: D000975:Antioxidants; D001786:Blood Glucose; D005947:Glucose
vernacular_title: Vliianie obshcheĭ upravliaemoĭ gipertermii na énergeticheskie resursy u onkologicheskikh bol'nykh.