title: [Enzyme activity in Leishmania].
abstract: Some enzymes produced by the protozoon Leishmania can have an important role in the intraphagocytic survival of the parasites. The production of hydrolytic enzymes by promastigotes belonging to two Leishmania sp. (major and infantum) and maintained in different experimental conditions was evaluated. The proteolytic activity was moderate, while superior was the production of acid phosphatase in L. infantum. An increase of the trypsin-like activity was observed after incubation of protozoa for 24 h at 37 degrees C, while a mouse injection did not changed the enzymatic activity of L. major.
authors.affiliation: Istituto di Microbiologia, Università di Torino.
authors.forename: D
authors.initials: D
authors.lastname: Savoia
authors.forename: S
authors.initials: S
authors.lastname: Biglino
authors.forename: A
authors.initials: A
authors.lastname: Cestaro
mesh_terms: D000818:Animals; D010450:Endopeptidases / Q000302:isolation & purification / Q000378:metabolism; D004950:Esterases / Q000302:isolation & purification / Q000378:metabolism; D006026:Glycoside Hydrolases / Q000302:isolation & purification / Q000378:metabolism; D007893:Leishmania donovani / Q000201:enzymology* / Q000254:growth & development / Q000472:pathogenicity; D007895:Leishmania tropica / Q000201:enzymology* / Q000254:growth & development / Q000472:pathogenicity; D051379:Mice; D010744:Phosphoric Monoester Hydrolases / Q000302:isolation & purification / Q000378:metabolism; D015800:Protozoan Proteins / Q000302:isolation & purification / Q000378:metabolism*; D014774:Virulence
chemical_list: D015800:Protozoan Proteins; D004950:Esterases; D010744:Phosphoric Monoester Hydrolases; D006026:Glycoside Hydrolases; D010450:Endopeptidases
vernacular_title: Attività enzimatica delle Leishmanie.