title: Evaluation of tartar control dentifrices in in vitro models of dentin sensitivity.
abstract: The effects of anticalculus dentifrices were compared with other commercially available dentifrices in in vitro models of dentin sensitivity. Changes in the hydraulic conductance of dentin discs were measured with and without a smear layer before and after treatment and also after a post-treatment acid etch. The capacity of dentifrices to occlude open dentinal tubules in vitro was also assessed by scanning electron microscopy (SEM). There was good correlation (R = 0.98) between our test and values reported in the literature. Tartar control dentifrices gave reductions in fluid flow rates through the dentin discs comparable to those obtained with Promise, Sensodyne, Thermodent and Denquel. Additionally, tartar control dentifrices did not remove microcrystalline debris (smear layers) from the surfaces of dentin in vitro. These results were confirmed by SEM. Thus, according to the hydrodynamic theory of dentin sensitivity, these in vitro results suggest that pyrophosphate-containing dentifrices should reduce dentinal sensitivity.
authors.forename: S
authors.initials: S
authors.lastname: Mason
authors.forename: A
authors.initials: A
authors.lastname: Levan
authors.forename: R
authors.initials: R
authors.lastname: Crawford
authors.forename: S
authors.initials: S
authors.lastname: Fisher
authors.forename: A
authors.initials: A
authors.lastname: Gaffar
mesh_terms: D003728:Dental Calculus / Q000517:prevention & control*; D003804:Dentin / Q000187:drug effects* / Q000502:physiology / Q000648:ultrastructure; D003807:Dentin Sensitivity / Q000209:etiology*; D011756:Diphosphates / Q000627:therapeutic use*; D006801:Humans; D066298:In Vitro Techniques; D008298:Maleates; D010070:Oxalates; D011145:Polyvinyls; D011713:Pyran Copolymer; D012044:Regression Analysis; D012212:Rheology; D014100:Toothpastes / Q000009:adverse effects*
chemical_list: D011756:Diphosphates; D008298:Maleates; D010070:Oxalates; D011145:Polyvinyls; D014100:Toothpastes; C058026:polyvinylmethoxyethylene-maleic anhydride copolymer; D011713:Pyran Copolymer