Chromoblastomycosis with malignant transformation and cutaneous-synovial secondary localization. The potential therapeutic role of itraconazole.
A case of neoplastic transformation of lesions of chromoblastomycosis is reported in a 67-year-old farmer from French Guyana. An interesting aspect of this case was the appearance of new cutaneous lesions of chromoblastomycosis, in a different site from the original lesion, and the presence of an infected synovial cyst. The potential therapeutic role of itraconazole is discussed.
Paul
C
C
Hospital of the Pasteur Institute, Paris, France.
Dupont
B
B
Pialoux
G
G
Avril
M F
MF
Pradinaud
R
R
D000368:Aged; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D002471:Cell Transformation, Neoplastic; D002862:Chromoblastomycosis / Q000188:drug therapy / Q000473:pathology*; D006172:Guyana; D006801:Humans; D017964:Itraconazole; D007654:Ketoconazole / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery; D013581:Synovial Cyst / Q000382:microbiology / Q000473:pathology
D000935:Antifungal Agents; D017964:Itraconazole; D007654:Ketoconazole