title: Chronic inflammatory demyelinating polyneuropathy in childhood: clinical and electrophysiological features.
abstract: Five children with chronic progressive polyneuropathy but no familial history of it showed electrophysiological evidence of demyelination with partial conduction block, temporal dispersion, and focal slowing of nerve conduction velocities in multiple nerves. These findings are indicative of an acquired demyelinating polyneuropathy that is chronic and inflammatory and differentiate this condition from most of the inherited neuropathies. It is very important to recognize this entity because of the availability of various treatments.
authors.affiliation: Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, New York.
authors.forename: A
authors.initials: A
authors.lastname: Uncini
authors.forename: E
authors.initials: E
authors.lastname: Parano
authors.forename: D J
authors.initials: DJ
authors.lastname: Lange
authors.forename: D C
authors.initials: DC
authors.lastname: De Vivo
authors.forename: R E
authors.initials: RE
authors.lastname: Lovelace
mesh_terms: D002648:Child; D002908:Chronic Disease; D003711:Demyelinating Diseases / Q000175:diagnosis* / Q000503:physiopathology*; D003937:Diagnosis, Differential; D004576:Electromyography; D005260:Female; D007839:Functional Laterality; D015417:Hereditary Sensory and Motor Neuropathy / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D008297:Male; D009132:Muscles / Q000294:innervation*; D009468:Neuromuscular Diseases / Q000175:diagnosis / Q000503:physiopathology; D010525:Peripheral Nerves / Q000503:physiopathology; D011115:Polyneuropathies / Q000175:diagnosis* / Q000503:physiopathology*; D011129:Polyradiculoneuropathy / Q000175:diagnosis / Q000503:physiopathology; D009435:Synaptic Transmission / Q000502:physiology*