title: [Intravital laboratory diagnosis of human subacute spongioid encephalopathies (Creutzfeldt-Jakob syndrome and amyotrophic leukospongiosis)].
abstract: Methods aimed at the detection of causative agents in the CSF and peripheral blood lymphocytes are recommended for the use in intravital laboratory diagnosis of slow infections of the central nervous system. The results obtained enable recommending the biotest on guinea-pigs or indication of the causative agent of amyotrophic leukospongiosis (AL) in cell culture coupled with the punctate immunoenzyme assay for the diagnosis of AL. As to the diagnosis of Creutzfeldt-Jacob disease, it is suggested that the biotest on guinea-pigs and the punctate immunoenzyme assay may be used.
authors.forename: N D
authors.initials: ND
authors.lastname: Kolomiets
authors.forename: E K
authors.initials: EK
authors.lastname: Mil'kamanovich
authors.forename: A G
authors.initials: AG
authors.lastname: Kolomiets
authors.forename: V P
authors.initials: VP
authors.lastname: Luchko
authors.forename: V V
authors.initials: VV
authors.lastname: Krishchanovich
authors.forename: I I
authors.initials: II
authors.lastname: Protas
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D001927:Brain Diseases / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000382:microbiology; D002555:Cerebrospinal Fluid / Q000382:microbiology; D007562:Creutzfeldt-Jakob Syndrome / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000382:microbiology; D004195:Disease Models, Animal; D006168:Guinea Pigs; D006801:Humans; D008214:Lymphocytes / Q000382:microbiology; D008875:Middle Aged; D012897:Slow Virus Diseases / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000382:microbiology; D014713:Viruses, Unclassified / Q000276:immunology / Q000302:isolation & purification
chemical_list: D000914:Antibodies, Viral
vernacular_title: Prizhiznennaia laboratornaia diagnostika podostrykh spongioznykh éntsefalopatiĭcheloveka (bolezni Kreĭttsfel'da-Jakoba i amiotroficheskogo leĭkospongioza).