Induction of an endothelial cell growth factor by human cytomegalovirus infection of fibroblasts.
Human cytomegalovirus (HCMV) induction of growth factors in fibroblasts was investigated after establishing serum-free culture conditions conducive to viral replication. HCMV infection induced a type II heparin-binding growth factor which stimulated human endothelial cell proliferation.
Alcami
J
J
Departement des Rétrovirus, Institut Pasteur, Paris, France.
Barzu
T
T
Michelson
S
S
D002455:Cell Division; D003587:Cytomegalovirus / Q000502:physiology*; D004730:Endothelium, Vascular / Q000166:cytology; D016222:Fibroblast Growth Factor 2 / Q000096:biosynthesis*; D005347:Fibroblasts / Q000378:metabolism / Q000382:microbiology; D006493:Heparin / Q000494:pharmacology; D006801:Humans; D007328:Insulin / Q000494:pharmacology; D013936:Thymidine / Q000378:metabolism; D014168:Transferrin / Q000494:pharmacology; D014779:Virus Replication
D007328:Insulin; D014168:Transferrin; D016222:Fibroblast Growth Factor 2; D006493:Heparin; D013936:Thymidine