Mechanism of site-specific DNA inversion in bacteria.
A wealth of new information regarding the structure of the synaptic complex, the mechanism of DNA strand exchange, and the role of the recombinational enhancer in promoting DNA inversion has been obtained from a combination of approaches. These include: electron microscopy of reaction intermediates, topological analysis of recombination products, and X-ray crystallography coupled with genetic analysis.
Johnson
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RC
Department of Biological Chemistry, UCLA School of Medicine 90024-1737.
D001419:Bacteria / Q000235:genetics*; D001426:Bacterial Proteins / Q000378:metabolism; D010583:Bacteriophage mu / Q000201:enzymology; D001483:Base Sequence; D002352:Carrier Proteins / Q000378:metabolism; D007446:Chromosome Inversion; D004254:DNA Nucleotidyltransferases / Q000378:metabolism; D004251:DNA Transposable Elements; D004269:DNA, Bacterial / Q000235:genetics* / Q000648:ultrastructure; D004742:Enhancer Elements, Genetic; D034982:Integration Host Factors; D008957:Models, Genetic; D008969:Molecular Sequence Data; D011995:Recombination, Genetic; D014764:Viral Proteins / Q000378:metabolism
D001426:Bacterial Proteins; D002352:Carrier Proteins; D004251:DNA Transposable Elements; D004269:DNA, Bacterial; D034982:Integration Host Factors; D014764:Viral Proteins; D004254:DNA Nucleotidyltransferases; C071957:Gin recombinase; C059997:Hin recombinase