[The possible participation of the cAMP system in the activation of ornithine decarboxylase in rat tissues following nonlethal fractionated gamma-irradiation].
A study was made of the activity of adenylate cyclase and cAMP-phosphodiesterase in rat thymus and liver various time intervals following nonlethal fractionated gamma-irradiation (2 Gy three times at a week interval). There was a positive correlation between the activity of cAMP metabolism enzymes and the radiation modification of ornithine decarboxylase (ODC) observed before. It is suggested that cAMP system is involved in ODC activity regulation in the exposed tissue.
Slozhenikina
L V
LV
Fialkovskaia
L A
LA
Ushakova
T E
TE
Kuzin
A M
AM
D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000502:physiology*; D000262:Adenylyl Cyclases / Q000502:physiology*; D000818:Animals; D003037:Cobalt Radioisotopes; D005260:Female; D005720:Gamma Rays; D008099:Liver / Q000201:enzymology*; D008297:Male; D009955:Ornithine Decarboxylase / Q000378:metabolism*; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains; D013950:Thymus Gland / Q000201:enzymology*
D003037:Cobalt Radioisotopes; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D009955:Ornithine Decarboxylase; D000262:Adenylyl Cyclases
O vozmozhnom uchasti sistemy tsAMF v aktivatsii ornitindekarboksilazy v tkaniakh krys posle neletal'nogo fraktsionirovannogo gamma-oblucheniia.