Determination of the relative binding free energies of peptide inhibitors to the HIV-1 protease.
Ferguson
D M
DM
University of California, Department of Pharmaceutical Chemistry, San Francisco 94143-0446.
Radmer
R J
RJ
Kollman
P A
PA
D001665:Binding Sites; D003460:Crystallization; D016333:HIV Protease / Q000737:chemistry / Q000378:metabolism; D017320:HIV Protease Inhibitors; D015497:HIV-1 / Q000201:enzymology*; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D009842:Oligopeptides / Q000737:chemistry / Q000378:metabolism*; D011480:Protease Inhibitors / Q000737:chemistry / Q000378:metabolism*; D011522:Protons; D013237:Stereoisomerism; D013816:Thermodynamics
D017320:HIV Protease Inhibitors; D009842:Oligopeptides; D011480:Protease Inhibitors; D011522:Protons; C066511:JG 365; D016333:HIV Protease