A means of retaining chromosome damage in irradiated human lymphocytes.
The method of premature chromosome condensation has been used to determine the damage induced by ionizing radiation to chromosomes in G1 human lymphocytes. The method has also demonstrated the repair of such damage with time following exposure. This study shows how storage at a cold temperature can be used to retain this damage for further biodosimetric study.
Maillie
H D
HD
Department of Biophysics, University of Rochester, NY 14642.
Baker
J V
JV
Watts
R J
RJ
Quinn
B R
BR
D000818:Animals; D002460:Cell Line; D006224:Cricetinae; D004249:DNA Damage; D004260:DNA Repair; D006801:Humans; D008214:Lymphocytes / Q000528:radiation effects*; D011829:Radiation Dosage; D013696:Temperature; D013997:Time Factors; D014021:Tissue Preservation