title: Streptococcal toxic shock syndrome in children.
abstract: Two children with toxic shock-like syndrome due to streptococcal infection are reported. In both cases (one fatal) the site of infection was in the soft tissues. Both strains of group A hemolytic streptococci isolated from blood culture produced large amounts of erythrogenic toxin B (ET B) small amounts of ET C but no ET A. This report confirms the implication of Streptococcus pyogenes in toxic shock like syndromes. When ET A seems to be responsible for most cases observed in the USA, our cases and others observed in Europe could be related to strains producing large amounts of ET B.
authors.affiliation: Unité de Réanimation Pédiatrique, Hopital Edouard Herriot, Lyon, France.
authors.forename: D
authors.initials: D
authors.lastname: Floret
authors.forename: D
authors.initials: D
authors.lastname: Stamm
authors.forename: P
authors.initials: P
authors.lastname: Cochat
authors.forename: P
authors.initials: P
authors.lastname: Delmas
authors.forename: W
authors.initials: W
authors.lastname: Kohler
mesh_terms: D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D012772:Shock, Septic / Q000209:etiology* / Q000382:microbiology / Q000628:therapy; D013290:Streptococcal Infections / Q000150:complications*; D013297:Streptococcus pyogenes