[The effect of carbacholine and pentagastrin on pancreatic secretory function during adaptation to a hyperlipemic diet].
Hyperlipemic diet (59% of fat) was found to increase the level of pancreatic secretion as well as its lipase activity in rats. The amylase and proteolytic enzyme activity was decreased. In hyperlipemic diet, carbachol and pentagastrin decreased the level of secretion and enzyme activity as compared with the balanced diet. Pentagastrin followed by atropine resulted in a considerable increase in lipase and proteolytic enzyme activity.
Kuznetsova
O A
OA
Nalivaĭko
D G
DG
Subbotin
Iu V
IuV
D000222:Adaptation, Physiological / Q000187:drug effects* / Q000502:physiology; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D002217:Carbachol / Q000494:pharmacology*; D004041:Dietary Fats / Q000008:administration & dosage*; D006949:Hyperlipidemias / Q000209:etiology / Q000503:physiopathology*; D010179:Pancreas / Q000187:drug effects* / Q000378:metabolism; D010418:Pentagastrin / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
D004041:Dietary Fats; D001285:Atropine; D002217:Carbachol; D010418:Pentagastrin
Vliianie karbakholina i pentagastrina na sekretornuiu funktsiiu podzheludochnoĭ zhelezy pri adaptatsii k giperlipemicheskoĭ diete.