title: Dose-response effects of recombinant bovine somatotropin implants on feedlot performance in steers.
abstract: One hundred twenty crossbred beef steers averaging 377 kg were used in a 2 x 4 factorial experiment to determine the dose-response effects of recombinant bovine somatotropin (rbST) implants on growth performance and carcass characteristics. The implant dosages were 0 (sham), 40, 80, or 160 mg/wk administered s.c. in the tailhead region on a weekly basis throughout the experiment. The steers were fed a high-concentrate diet, which contained either a degradable (DP; soybean meal) or an escape (EP; corn gluten and blood meal) protein source. No dietary protein effect or dietary protein x rbST level interactions were detected. Recombinant bST decreased both DMI (P less than .10) and feed/gain (P less than .05) in a linear dose-dependent manner. Dosage of rbST did not significantly affect (P greater than .10) ADG or final weight of the steers. Recombinant bST decreased backfat depth (P less than .10), marbling score (P less than .05), and quality grade (P less than .10) and increased yield grade (P less than .10) in a linear dose-dependent manner. Soft tissue composition of the 9-10-11th rib section was altered (P less than .01) by rbST administration in a linear dose-dependent manner. The percentage of protein in the rib section was increased by 9.4% and fat was decreased by 11.8% at the 160 mg/wk rbST level compared with the sham-implanted steers. Recombinant bST did not affect (P greater than .10) dressing percentage, hot carcass weight, kidney, pelvic, and heart fat, or longissimus muscle area.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Animal and Veterinary Science, University of Idaho, Moscow 83843.
authors.forename: B S
authors.initials: BS
authors.lastname: Dalke
authors.forename: R A
authors.initials: RA
authors.lastname: Roeder
authors.forename: T R
authors.initials: TR
authors.lastname: Kasser
authors.forename: J J
authors.initials: JJ
authors.lastname: Veenhuizen
authors.forename: C W
authors.initials: CW
authors.lastname: Hunt
authors.forename: D D
authors.initials: DD
authors.lastname: Hinman
authors.forename: G T
authors.initials: GT
authors.lastname: Schelling
mesh_terms: D000273:Adipose Tissue / Q000187:drug effects / Q000254:growth & development; D000818:Animals; D001823:Body Composition / Q000187:drug effects; D002417:Cattle / Q000254:growth & development*; D004044:Dietary Proteins / Q000008:administration & dosage; D004305:Dose-Response Relationship, Drug; D004343:Drug Implants; D004435:Eating; D013006:Growth Hormone / Q000008:administration & dosage / Q000494:pharmacology*; D007334:Insulin-Like Growth Factor I / Q000032:analysis; D008297:Male; D008460:Meat / Q000592:standards; D009124:Muscle Proteins / Q000096:biosynthesis; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000494:pharmacology; D015430:Weight Gain / Q000187:drug effects
chemical_list: D004044:Dietary Proteins; D004343:Drug Implants; D009124:Muscle Proteins; D011994:Recombinant Proteins; D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone