title: Epithelial salivary gland tumors of children and adolescents in southern Portugal. A clinicopathologic study of twenty-four cases.
abstract: During a 30-year period 24 epithelial salivary gland tumors were diagnosed in children and adolescents less than 18 years of age. The cases were retrieved from a series of 759 consecutive cases of salivary gland tumors (3.2%) from the area corresponding to southern Portugal during the same period of time. The mean age of the patients was 13.4 years, and one case was congenital. There was a slight female predominance (male/female ratio 1:1.7). The parotid gland was affected in most cases (70.8%). Seventeen neoplasms were benign, and the remaining seven were malignant. As in the adult group, pleomorphic adenoma was the most frequent benign tumor (66.6%), with similar histologic findings and clinical course. Mucoepidermoid carcinoma was the prevalent malignant tumor (20.8%), had a high grade of differentiation, and had a favorable outcome. The histologic pattern of the congenital neoplasm was similar to that of adult epithelial-myoepithelial carcinoma.
authors.affiliation: Serviço de Patologia Morfológica, Instituto Portuguès de Oncologia, Lisbon.
authors.forename: I
authors.initials: I
authors.lastname: Fonseca
authors.forename: A G
authors.initials: AG
authors.lastname: Martins
authors.forename: J
authors.initials: J
authors.lastname: Soares
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology*; D000293:Adolescent; D002277:Carcinoma / Q000473:pathology*; D003528:Carcinoma, Adenoid Cystic / Q000473:pathology; D002648:Child; D003537:Cystadenoma / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010307:Parotid Neoplasms / Q000151:congenital; D011174:Portugal / Q000453:epidemiology; D012468:Salivary Gland Neoplasms / Q000453:epidemiology / Q000473:pathology*