title: Expression of Escherichia coli F-18 type 1 fimbriae in the streptomycin-treated mouse large intestine.
abstract: Escherichia coli F-18, isolated from the feces of a healthy human, makes type 1 fimbriae and is an excellent colonizer of the streptomycin-treated mouse large intestine. Recently, it was shown that the inability to produce type 1 fimbriae had no effect on the ability of E. coli F-18 to colonize the streptomycin-treated mouse large intestine, suggesting the possibility that E. coli F-18 does not express type 1 fimbriae in vivo. However, we show here that E. coli F-18 does express type 1 fimbriae in mouse cecal mucus in vivo and, in fact, appears to express substantially more type 1 fimbriae in cecal mucus in vivo than in L broth in vitro.
authors.affiliation: Department of Microbiology, Technical University of Denmark, Lyngby.
authors.forename: K A
authors.initials: KA
authors.lastname: Krogfelt
authors.forename: B A
authors.initials: BA
authors.lastname: McCormick
authors.forename: R L
authors.initials: RL
authors.lastname: Burghoff
authors.forename: D C
authors.initials: DC
authors.lastname: Laux
authors.forename: P S
authors.initials: PS
authors.lastname: Cohen
mesh_terms: D000818:Animals; D002432:Cecum / Q000382:microbiology*; D004926:Escherichia coli / Q000502:physiology*; D010861:Fimbriae, Bacterial / Q000502:physiology*; D051379:Mice; D013307:Streptomycin / Q000494:pharmacology*
chemical_list: D013307:Streptomycin