Treatment of genital condylomata with topical 5-fluorouracil.
Use of topical 5-FU is indicated for therapy-resistant condylomata and for extensive untreated vulvar condylomata. It may be the treatment of choice for extensive or therapy-resistant vaginal condylomata. Applications of 5-FU once weekly to the vagina and twice weekly to the vulva for 10 weeks appear to be as effective as continued regimens but are better tolerated. Perhaps the greatest value of 5-FU lies in periodic application for prevention of recurrences of condylomata removed by surgical methods.
Krebs
H B
HB
Department of Obstetrics and Gynecology, George Washington University Hospital, DC.
D000287:Administration, Topical; D001005:Anus Neoplasms / Q000188:drug therapy; D003131:Combined Modality Therapy; D003218:Condylomata Acuminata / Q000188:drug therapy* / Q000601:surgery; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D005833:Genital Neoplasms, Female / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D053685:Laser Therapy; D027383:Papillomaviridae; D014412:Tumor Virus Infections / Q000188:drug therapy* / Q000601:surgery; D014523:Urethral Neoplasms / Q000188:drug therapy; D014625:Vaginal Neoplasms / Q000188:drug therapy; D014846:Vulvar Neoplasms / Q000188:drug therapy
D005472:Fluorouracil