title: Angiosarcoma of the irradiated breast: a new problem after breast conserving therapy?
abstract: Post-irradiation angiosarcoma of the breast is an uncommon neoplasm. The first patient with this disease after breast conserving therapy was reported in 1987 and only a few more patients can be traced in the literature since that time. Two more cases are presented in this paper: both women in the seventh decade of life. The tumour became apparent five and seven years after the primary treatment of breast cancer. The possible influence of irradiation and lymphoedema in inducing this malignancy is discussed.
authors.affiliation: Department of Surgery, Elisabeth Hospital, The Netherlands.
authors.forename: J A
authors.initials: JA
authors.lastname: Roukema
authors.forename: L P
authors.initials: LP
authors.lastname: Leenen
authors.forename: M C
authors.initials: MC
authors.lastname: Kuizinga
authors.forename: B
authors.initials: B
authors.lastname: Maat
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000209:etiology / Q000473:pathology / Q000532:radiotherapy*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000532:radiotherapy*; D005260:Female; D006394:Hemangiosarcoma / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D011832:Radiation Injuries / Q000209:etiology*