[Proliferative processes in nerve tissue culture under the action of ethanol].
The authors describe the ultrastructure of an organotypic culture of rat brain cortex exposed to small doses of ethanol. It is shown that the small dose of alcohol (0.5% ethanol) present in the nutrient medium induced proliferation of cytoplasmic membrane structure: hyperplasia of the endoplasmic reticulum with the formation of concentrically located membranes; an increase of the number and size of mitochondria was accompanied by the appearance of the giant, atypical forms of mitochondria; proliferation of vesicular components of Golgi's laminar complex.
Konovalov
G V
GV
Mel'nikova
T N
TN
Chubakov
A R
AR
D000818:Animals; D000831:Animals, Newborn; D002455:Cell Division / Q000187:drug effects; D046508:Culture Techniques; D000431:Ethanol / Q000494:pharmacology*; D008854:Microscopy, Electron; D009044:Motor Cortex / Q000187:drug effects / Q000648:ultrastructure; D009417:Nerve Tissue / Q000187:drug effects* / Q000648:ultrastructure; D051381:Rats; D013997:Time Factors
D000431:Ethanol
Proliferativnye protsessy v kul'ture nervnoĭ tkani pri deĭstvii étanola.