Transcriptional activation by viral regulatory proteins.
The control of transcription involves the use of many transcriptional regulatory proteins. Viral systems and proteins have been used as models to gain insight into these control processes. These include the adenovirus E1A13S and E1A12S products and the herpes virus VP16 protein. This review examines these diverse mechanisms, but also explores the elements of commonality between them.
Nevins
J R
JR
Howard Hughes Medical Institute, Department of Microbiology and Immunology, Duke University Medical Center, Durham, NC 27710.
D000260:Adenoviruses, Human / Q000235:genetics; D001483:Base Sequence; D004268:DNA-Binding Proteins / Q000235:genetics; D015967:Gene Expression Regulation, Viral / Q000235:genetics*; D008969:Molecular Sequence Data; D018139:Simplexvirus / Q000235:genetics; D015534:Trans-Activators; D014157:Transcription Factors / Q000235:genetics
D004268:DNA-Binding Proteins; D015534:Trans-Activators; D014157:Transcription Factors