[Investigation of human cytomegalovirus infection in 103 cases with history of abnormal pregnancy].
Human cytomegalovirus (HCMV)-IgG, IgM antibodies were detected by indirect ELISA in 103 serum specimens from women with history of abnormal pregnancy. The results showed that the positive rates of HCMV-IgG and IgM of abnormal pregnant women were 90.29% and 13.59% respectively. The positive rate of HCMV-IgM in abnormal pregnancies was higher than that of normal pregnancies (4.07%, P less than 0.001). This suggested that the probability of abnormal pregnancy in HCMV-IgM positive women was higher than the negative ones. Thus detecting HCMV-IgM by ELISA could be used not only in early diagnosis of active HCMV infection in pregnant women, but also a way to prevent this delivery of malformed babies.
Xu
G L
GL
Shanghai Second Medical University.
D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D002681:China / Q000453:epidemiology; D003587:Cytomegalovirus / Q000276:immunology / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000453:epidemiology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D015994:Incidence; D011247:Pregnancy; D011248:Pregnancy Complications
D000914:Antibodies, Viral; D007075:Immunoglobulin M