Signal transduction pathways controlling multicellular development in Dictyostelium.
The importance of signal transduction pathways in regulating developmental processes in a number of organisms has become evident in recent years. This is exceptionally clear for Dictyostelium, which uses soluble factors to regulate morphogenesis and cellular differentiation. It is now known that many of these processes are controlled by signal transduction pathways mediated by cyclic AMP through cell surface receptors coupled to G proteins, and that others are mediated by the morphogen DIF.
Firtel
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Department of Biology, University of California, San Diego, La Jolla 92093-0634.
D000818:Animals; D002465:Cell Movement; D000242:Cyclic AMP / Q000502:physiology; D004023:Dictyostelium / Q000254:growth & development*; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism; D019204:GTP-Binding Proteins / Q000502:physiology; D015966:Gene Expression Regulation, Fungal; D005800:Genes, Fungal; D008954:Models, Biological; D012098:Reproduction; D015398:Signal Transduction
D005656:Fungal Proteins; D000242:Cyclic AMP; D019204:GTP-Binding Proteins