Chronic alpha 1 blockade in a patient with Eisenmenger syndrome.
In an 18-year-old male with Eisenmenger syndrome cyanosis and erythrocytosis were increasing. The erythrocytosis diminished following oral bunazosin and phlebotomy was not needed during the treatment. When bunazosin was stopped, the erythrocytosis increased, but when it was resumed, the erythrocytosis and general fatigue diminished.
Watanabe
K
K
Department of Pediatrics, Shimane Medical University, Izumo, Japan.
Mori
C
C
Haneda
N
N
Inoue
M
M
Kishida
K
K
Hayashi
Y
Y
Ozasa
H
H
D000293:Adolescent; D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use*; D004541:Eisenmenger Complex / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008297:Male; D011799:Quinazolines / Q000627:therapeutic use*
D000317:Adrenergic alpha-Antagonists; D011799:Quinazolines; C018176:bunazosin