title: Depicting topology and handedness in jellyroll structures.
abstract: The jellyroll structure is a special case of the Greek key topology and, to date, has only been observed in complete form in one of its four possible arrangements. Like other elements of super-secondary structure involving the beta-strand (e.g. the beta alpha beta unit) the known structure forms a right-handed superhelix. The possibility of losing such tertiary information and other problems associated with representing these structures by two-dimensional topology diagrams are discussed. A series of rules are presented which allow this three-dimensional information to be represented in two-dimensional topology diagrams from which the handedness of a jellyroll structure can be determined.
authors.affiliation: Department of Biochemistry and Molecular Biology, University College, London, UK.
authors.forename: H J
authors.initials: HJ
authors.lastname: Stirk
authors.forename: D N
authors.initials: DN
authors.lastname: Woolfson
authors.forename: E G
authors.initials: EG
authors.lastname: Hutchinson
authors.forename: J M
authors.initials: JM
authors.lastname: Thornton
mesh_terms: D011487:Protein Conformation