title: [The protective action of arbidol during a rise in respiratory diseases in 1990].
abstract: Prophylactic properties of a new chemical drug, arbidol, against acute respiratory diseases (ARD) were studied. Arbidol given daily in a dose of 0.2 g for 19 days reduced the morbidity rate 2.3-fold in adults during an outbreak of ARD. Geometric mean titres of antibodies to respiratory viruses among healthy persons did not change after treatment with arbidol indicating the lack of immunosuppressive properties in the drug. The prophylactic effect of arbidol may be due to both specific effect of the drug on influenza and parainfluenza viruses, and its interferon-inducing and immunity-stimulating properties.
authors.forename: N P
authors.initials: NP
authors.lastname: Obrosova-Serova
authors.forename: E I
authors.initials: EI
authors.lastname: Burtseva
authors.forename: I M
authors.initials: IM
authors.lastname: Nevskiĭ
authors.forename: R I
authors.initials: RI
authors.lastname: Karmanova
authors.forename: V I
authors.initials: VI
authors.lastname: Nazarov
authors.forename: A A
authors.initials: AA
authors.lastname: Pitkenen
authors.forename: A N
authors.initials: AN
authors.lastname: Slepushkin
mesh_terms: D000208:Acute Disease; D000260:Adenoviruses, Human / Q000276:immunology; D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D000998:Antiviral Agents / Q000627:therapeutic use*; D004196:Disease Outbreaks; D004341:Drug Evaluation; D006801:Humans; D009980:Influenza A virus / Q000276:immunology; D009981:Influenza B virus / Q000276:immunology; D007251:Influenza, Human / Q000188:drug therapy / Q000453:epidemiology / Q000276:immunology; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000453:epidemiology / Q000276:immunology; D018108:Respirovirus / Q000276:immunology; D014586:USSR / Q000453:epidemiology
chemical_list: D000914:Antibodies, Viral; D000998:Antiviral Agents
vernacular_title: Izuchenie zashchitnogo deĭstviia arbidola vo vremia pod''ema respiratornykh zabolevaniĭ v 1990 g.