title: The ion-conducting properties of Ca2+ ATPase in rabbit skeletal muscle sarcoplasmic reticulum.
abstract: Ca2+ ATPase was isolated from rabbit skeletal muscle sarcoplasmic reticulum and used to form structures resembling potential-dependent calcium channels within the membrane lipid bilayer of liposomes. The orientation of these structures in the bilayer was dependent on the conditions used for enzyme incorporation. The results obtained indicate that Ca2+ ATPase may be involved in the passive transport of calcium ions from the sarcoplasmic reticulum which may be regulated by the membrane potential. The membrane potential within the reticulum is probably positive at the moment of calcium ion release.
authors.affiliation: Palladin Institute of Biochemistry, Academy of Sciences of the Ukrainian SSR, Kiev.
authors.lastname: Shaturskii OYa
authors.forename: M D
authors.initials: MD
authors.lastname: Kurskii
authors.forename: A N
authors.initials: AN
authors.lastname: Fedorov
authors.forename: V B
authors.initials: VB
authors.lastname: Piskarev
authors.forename: A N
authors.initials: AN
authors.lastname: Chanturiya
mesh_terms: D000818:Animals; D015220:Calcium Channels / Q000201:enzymology* / Q000502:physiology; D000252:Calcium-Transporting ATPases / Q000502:physiology*; D004553:Electric Conductivity; D007425:Intracellular Membranes / Q000502:physiology; D008051:Lipid Bilayers / Q000378:metabolism; D008563:Membrane Lipids / Q000502:physiology; D008564:Membrane Potentials / Q000502:physiology; D011817:Rabbits; D012519:Sarcoplasmic Reticulum / Q000201:enzymology* / Q000502:physiology
chemical_list: D015220:Calcium Channels; D008051:Lipid Bilayers; D008563:Membrane Lipids; D000252:Calcium-Transporting ATPases