[Level of specific IgE and IgG in blood serum of patients with hay fever after several cycles of desensitization with pollinex vaccine].
Blood serum specific IgE and IgG levels have been assayed in a group of 54 patients allergic to grass pollen during the long-lasting desensitization with Pollinex Depot vaccine. Specific IgE and IgG levels were determined with RAST and IgG-RAST technique whereas a titre of the blocking antibodies with RAST inhibition test. It was found that cyclic administration of Pollinex vaccine, repeated every 3-4 years, significantly influences patients' immunologic system manifested by a decrease in specific IgE, and an increase in both IgG level and the titre of the blocking antibodies.
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Kliniki Alergologii AM, Białymstoku.
D000293:Adolescent; D000328:Adult; D000485:Allergens / Q000627:therapeutic use*; D052179:Antigens, Plant / Q000627:therapeutic use; D003692:Delayed-Action Preparations; D004338:Drug Combinations; D005260:Female; D005976:Glutaral / Q000008:administration & dosage*; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood*; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000008:administration & dosage*; D011058:Pollen / Q000276:immunology*; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy* / Q000276:immunology*; D014443:Tyrosine / Q000008:administration & dosage*
D000485:Allergens; D052179:Antigens, Plant; D003692:Delayed-Action Preparations; D004338:Drug Combinations; D007074:Immunoglobulin G; D010936:Plant Extracts; D007073:Immunoglobulin E; D014443:Tyrosine; C014155:Parietaria judaica pollen; D005976:Glutaral
Stezenie swoistych IgE i IgG w surowicy chorych na pyłkowice po kilku cyklach odczulania szczepionka alergenowa Pollinex.