title: Antigenic variation of pseudorabies virus glycoproteins g II and g III demonstrated by neutralizing monoclonal antibodies.
abstract: Antigenic variation of pseudorabies virus glycoprotein g II was demonstrated in field isolates by neutralizing monoclonal antibodies. Mutants capable of avoiding neutralization by the monoclonal antibodies specific for glycoproteins g II and g III could be obtained from the parent virus by mutagenesis.
authors.affiliation: Second Research Division, National Institute of Animal Health, Ibaraki, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Yamada
authors.forename: T
authors.initials: T
authors.lastname: Imada
authors.forename: T
authors.initials: T
authors.lastname: Nishimori
authors.forename: K
authors.initials: K
authors.lastname: Sekikawa
authors.forename: M
authors.initials: M
authors.lastname: Shimizu
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal; D000940:Antigenic Variation; D005455:Fluorescent Antibody Technique; D011558:Herpesvirus 1, Suid / Q000235:genetics / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D016296:Mutagenesis; D009500:Neutralization Tests; D014759:Viral Envelope Proteins / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D014759:Viral Envelope Proteins; C042966:pseudorabies virus glycoproteins