The gene for the type II (p75) tumor necrosis factor receptor (TNF-RII) is localized on band 1p36.2-p36.3.
The gene encoding the type II (p75) tumor necrosis factor receptor (TNF-RII) has been localized on human chromosome 1, band 1p36.2 by nonradioactive in situ hybridization. The gene encoding the type I (p55) TNF-R, which is structurally homologous to the type II (p75) TNF-R, has been previously localized on chromosome 12 band 12p13. Thus, despite their probable common ancestry, the genes for the two TNF-Rs are localized on different chromosomes.
Kemper
O
O
Department of Molecular Genetics and Virology, Weitzmann Institute of Science, Rehovot, Israel.
Derré
J
J
Cherif
D
D
Engelmann
H
H
Wallach
D
D
Berger
R
R
D001483:Base Sequence; D002878:Chromosomes, Human, Pair 1; D015342:DNA Probes; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D011956:Receptors, Cell Surface / Q000235:genetics*; D018124:Receptors, Tumor Necrosis Factor
D015342:DNA Probes; D011956:Receptors, Cell Surface; D018124:Receptors, Tumor Necrosis Factor