Human leucocyte antigens and tardive dyskinesia.
HLA status was assessed in matched groups of schizophrenics, 20 with and 20 without tardive dyskinesia. The antigen frequencies were also compared with that in a control sample. The anticipated excess of HLA-B44 was not confirmed. Pooled data displayed a shortfall of HLA-Cw7 and an excess of HLA-B44 in schizophrenics relative to population controls.
Brown
K W
KW
Royal Edinburgh Hospital.
White
T
T
D000328:Adult; D000368:Aged; D014150:Antipsychotic Agents / Q000009:adverse effects; D004409:Dyskinesia, Drug-Induced / Q000209:etiology / Q000276:immunology*; D005260:Female; D005787:Gene Frequency; D005838:Genotype; D006680:HLA Antigens / Q000235:genetics / Q000276:immunology*; D015235:HLA-B Antigens / Q000235:genetics / Q000276:immunology; D059948:HLA-B44 Antigen; D015236:HLA-C Antigens / Q000235:genetics / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000188:drug therapy / Q000276:immunology*
D014150:Antipsychotic Agents; D006680:HLA Antigens; D015235:HLA-B Antigens; D059948:HLA-B44 Antigen; D015236:HLA-C Antigens; C040178:HLA-C*70 antigen