title: [Alexander's disease].
abstract: Alexander disease, or hypoproconvertinemia is a rare autosomic recessive coagulation disorder. The features include familial and/or personal history of bleeding, with an abnormal prothrombin period and a normal activated partial thromboplastin period. Coagulation and genetic studies allow subclassification with prognosis incidence for this disease. The authors report on a case of one family with Alexander disease.
authors.affiliation: Service de chimiothérapie massive et greffe de moelle, hôpital nord, Saint Prietz en Jarez, France.
authors.forename: J C
authors.initials: JC
authors.lastname: Elian
authors.forename: D
authors.initials: D
authors.lastname: Frappaz
authors.forename: J
authors.initials: J
authors.lastname: Reynaud
authors.forename: S
authors.initials: S
authors.lastname: Perrot
authors.forename: F
authors.initials: F
authors.lastname: Freycon
mesh_terms: D002648:Child; D005168:Factor VII Deficiency / Q000150:complications / Q000235:genetics* / Q000276:immunology; D014644:Genetic Variation; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D008297:Male
vernacular_title: La maladie d'Alexander.