Genetics of post-hatching survival potential of Australorp chicks infected as embryos by subgroup A Rous sarcoma virus: further support to 4-allele genetic model.
Embryos (II day-old) of Australorp breed were inoculated via chorioallantoic membrane (CAM) with subgroup A Rous sarcoma virus, and hatched subsequently. The post-hatch survival period in chicks was recorded upto the last chick that died by virus-induced liver tumour, which had a range from 3 to 50 days with an average of 13 +/- 8.7 days. The survival potential of progency tested Australorp parents selected on the basis of negative CAM-infection and those selected on uninoculated embryos, differed significantly (P less than 0.01) while maintaining an inverse relationship between liver tumour mortality and degrees of infection of CAMs. The homozygous susceptibles lacking either ar1 or ar2 or both alleles of the tva (tumour virus a) locus died within 7 days of post-hatching, supporting thereby 4-allele genetic model of tva locus recently proposed for the control of LT- and CAM-infection phenotypes.
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PL-480 Project, Indian Veterinary Research Institute, Izatnagar.
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D000483:Alleles; D000818:Animals; D002642:Chick Embryo; D002645:Chickens / Q000235:genetics* / Q000254:growth & development; D008957:Models, Genetic; D011201:Poultry Diseases / Q000235:genetics* / Q000401:mortality; D001357:Sarcoma, Avian / Q000235:genetics* / Q000401:mortality