Aplasia cutis congenita associated with syndactyly and supernumerary nipples: report of a second family with similar clinical findings.
Aplasia cutis congenita (ACC) is a rare disorder characterized by localized absence of skin at birth. A subtype consisting of a solitary scalp defect in association with limb abnormalities has been described. We report a case of ACC in association with 3,4 syndactyly and supernumerary nipples with an apparent autosomal dominant inheritance pattern.
Halper
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S
University of Chicago, Department of Medicine, Section of Dermatology, Illinois 60637.
Rubenstein
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D
D000015:Abnormalities, Multiple / Q000235:genetics*; D004476:Ectodermal Dysplasia / Q000235:genetics*; D006801:Humans; D007223:Infant; D008297:Male; D009558:Nipples / Q000002:abnormalities*; D013576:Syndactyly / Q000235:genetics*