[Vegetative nervous system's contribution to the development of stress induced gastric ulcers].
A vegetative nervous system contribution to the development of stress-induced gastric ulcers has been investigated. The experiments involved male Wistar rats. Vegetative nervous system activity has been assessed with acetylcholine brain and stomach tissue levels and synthesis as well as adrenaline and noradrenaline levels in adrenals and gastric wall. The results have shown, that ulcerogenic effect of stress is accompanied by the increase in both cholinergic and adrenergic activities. Moreover, it has been shown, that markedly strong stimulation of the adrenergic system in some rats, together with pharmacologic activation of alpha-adrenergic receptors, inhibits the development of stress-induced gastric ulcers.
Pielecka
Z
Z
Kliniki Ogólnej Chorób Wewnetrznych Instytutu Chorób Wewnetrznych.
Hanzlik
J
J
Górny
D
D
Jakiel
A
A
D000109:Acetylcholine / Q000378:metabolism*; D000311:Adrenal Glands / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000378:metabolism; D004837:Epinephrine / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism; D008297:Male; D009638:Norepinephrine / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D013276:Stomach Ulcer / Q000209:etiology* / Q000378:metabolism; D013312:Stress, Physiological / Q000150:complications* / Q000378:metabolism
D000109:Acetylcholine; D009638:Norepinephrine; D004837:Epinephrine
Udział wegetatywnego układu nerwowego w powstawaniu stresowych wrzodów zoładka.