[Generation of active oxygen compounds by whole blood granulocytes in patients with chronic renal failure].
In patients with chronic renal failure (crf) on conservative treatment whole blood granulocyte superoxide anion (O2-) generation was significantly decreased. Regular hemodialysis treatment did not induce its significant improvement. As granulocyte O2- generation determines production of other active oxygen compounds, this phenomenon may lead to the impairment of phagocyte bactericidal activity and increased susceptibility to infections in crf. Various methods of determination of active oxygen compounds give incomparable results.
Pawlicki
L
L
II Klinika Chorób Wewnetrznych WAM w Lodzi.
Trznadel
K
K
Kedziora
J
J
Błaszczyk
J
J
Sibińska
E
E
Luciak
M
M
D000293:Adolescent; D000328:Adult; D005260:Female; D005609:Free Radicals; D006801:Humans; D006861:Hydrogen Peroxide / Q000097:blood* / Q000378:metabolism; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000378:metabolism*; D006435:Renal Dialysis; D013481:Superoxides / Q000097:blood* / Q000378:metabolism
D005609:Free Radicals; D013481:Superoxides; D006861:Hydrogen Peroxide
Generacja aktywnych zwiazków tlenowych przez granulocyty krwi pełnej u chorych z przewlekła niewydolnościa nerek.