title: The use of vidarabine in the treatment of human polyomavirus associated acute haemorrhagic cystitis.
abstract: The human BK and JC polyomaviruses are known to be reactivated and excreted in the urine following bone marrow transplantation (BMT). A proportion of patients who excrete BK virus following BMT experience a haemorrhagic cystitis (HC), which may persist for many months. We report a case of human polyomavirus-associated HC, in whom treatment with vidarabine was associated with a dramatic response.
authors.affiliation: Department of Haematology, Leicester Royal Infirmary, UK.
authors.forename: C
authors.initials: C
authors.lastname: Chapman
authors.forename: A J
authors.initials: AJ
authors.lastname: Flower
authors.forename: S T
authors.initials: ST
authors.lastname: Durrant
mesh_terms: D000208:Acute Disease; D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects; D003556:Cystitis / Q000150:complications* / Q000188:drug therapy; D006470:Hemorrhage / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008297:Male; D011120:Polyomavirus; D014412:Tumor Virus Infections / Q000150:complications / Q000188:drug therapy* / Q000209:etiology; D014740:Vidarabine / Q000627:therapeutic use*
chemical_list: D014740:Vidarabine