Eosinophilia associated with a composite lymphoma.
We report a case of composite lymphoma heralded by a hyper-eosinophilia syndrome. Combination of immunophenotyping and gene rearrangement analysis allowed us to confirm malignancy and to detect a minor oligoclone B within a malignant T-cell predominant population. No evidence of retroviral infection was found using western blot and gene amplification techniques.
Merlio
J P
JP
Pathology Laboratory, Hôpital Saint-André, Bordeaux, France.
De Mascarel
A
A
Astier-Gin
T
T
Michenet
P
P
Beylot
C
C
Beylot
J
J
D000328:Adult; D004802:Eosinophilia / Q000209:etiology / Q000473:pathology*; D015333:Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; D006801:Humans; D007119:Immunoblastic Lymphadenopathy / Q000150:complications / Q000235:genetics / Q000473:pathology; D016130:Immunophenotyping; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000175:diagnosis; D008223:Lymphoma / Q000150:complications / Q000235:genetics* / Q000473:pathology; D008297:Male