title: Distribution of the 1,25 dihydroxy-vitamin D3 receptor in the bursa of Fabricius of chicken.
abstract: The vitamin D3 metabolite 1,25(OH)2D3 is probably involved in B lymphocyte ontogeny. We therefore determined the distribution of the 1,25(OH)2D3 receptor in the bursa of Fabricius and spleen cells of 7-day-old chicks, by immunohistochemistry using a monoclonal antibody against the chick intestinal cell 1,25(OH)2D3 receptor. The bursa cells of young (7-day-old) chicks contained large amounts of receptor while the spleen cells did not. The bursa cells of older (35-day-old) chicks contained fewer receptors, but the number of receptors in the spleen increased.
authors.affiliation: Chair of Histology and Embryology, Faculty of Medicine, University of Pisa, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Petrini
authors.forename: F
authors.initials: F
authors.lastname: Bianchi
authors.forename: A
authors.initials: A
authors.lastname: Dolfi
authors.forename: M
authors.initials: M
authors.lastname: Lupetti
mesh_terms: D000375:Aging / Q000378:metabolism; D000818:Animals; D002060:Bursa of Fabricius / Q000254:growth & development / Q000378:metabolism*; D002645:Chickens; D007124:Immunoenzyme Techniques; D018167:Receptors, Calcitriol; D011987:Receptors, Steroid / Q000378:metabolism*; D013154:Spleen / Q000254:growth & development / Q000378:metabolism
chemical_list: D018167:Receptors, Calcitriol; D011987:Receptors, Steroid