Rhabdomyosarcoma associated with familial adenomatous polyposis.
We report a case of a 16 year old girl with orbital rhabdomyosarcoma who during chemotherapy developed bloody diarrhoea. On investigation she was found to have multiple colonic polyps. Cytogenetic analysis has shown a pattern typical of familial adenomatous polyposis. We present a review of the literature concerning the associations of familial adenomatous polyposis. The association of familial adenomatous polyposis with rhabdomyosarcoma has not been previously reported.
Armstrong
S J
SJ
Department of Radiodiagnosis, Bristol Royal Hospital for Sick Children, UK.
Duncan
A W
AW
Mott
M G
MG
D011125:Adenomatous Polyposis Coli / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D000293:Adolescent; D005260:Female; D006801:Humans; D009378:Neoplasms, Multiple Primary; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy; D011859:Radiography; D012208:Rhabdomyosarcoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy