[Status of the T-lymphocyte system of immunity in patients with newly diagnosed paroxysmal schizophrenia].
Overall 19 male patients with attack-like schizophrenia were examined within the first 1-2 months since the disease manifestation till the onset of the antipsychotic treatment. To characterize the T immunity system, use was made of the E-rosette formation test and a kit of monoclonal antibodies. It has been revealed, that in the peripheral blood of the schizophrenic patients, the T lymphocyte count was noticeably decreased, the relative count of the cells of both the regulatory populations was increased, being statistically significant only for helpers. The ratio of T helpers to T suppressors remained unchanged. The count of poorly differentiated T lymphocytes turned out noticeably increased.
Rogozhnikova
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D000293:Adolescent; D000328:Adult; D006801:Humans; D007958:Leukocyte Count; D008231:Lymphopenia / Q000175:diagnosis / Q000209:etiology*; D008297:Male; D012397:Rosette Formation; D012560:Schizophrenia, Catatonic / Q000175:diagnosis / Q000276:immunology*; D012563:Schizophrenia, Paranoid / Q000175:diagnosis / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology* / Q000473:pathology; D013997:Time Factors
Sostoianie T-sistemy immuniteta u bol'nykh s vpervye diagnosti- rovannoĭ pristupoobraznoĭ shizofrenieĭ.