[Levels of ACTH and cortisol in patients with kidney transplantation examined during water immersion].
Influence of water immersion (WI) on ACTH and cortisol levels in 64 kidney transplant patients (KTP) (35 treated by cyclosporine A and prednisone and 29 by azathioprine and prednisone) and 15 healthy subjects were measured. Plasma cortisol level was lower, but ACTH normal in KTP. WI in all groups induced significantly decrease plasma ACTH and cortisol levels. This decrease was higher in controls than in KTP only in healthy subjects a significant correlation between ACTH and cortisol was present. Our results suggest: 1. dissociation pituitary-suprarenal function in KTP; 2. influence of immunosuppressive therapy on ACTH and cortisol levels after WI.
Zukowska-Szczechowska
E
E
Katedry i Kliniki Nefrologii Slaşkiej Akademii Medycznej.
Kokot
F
F
Grzeszczak
W
W
D000324:Adrenocorticotropic Hormone / Q000097:blood*; D000328:Adult; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D007101:Immersion / Q000503:physiopathology*; D007165:Immunosuppression Therapy; D016030:Kidney Transplantation / Q000502:physiology*; D008297:Male; D012016:Reference Values
D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone
Stezenie ACTH i kortyzolu u chorych z przeszczepiona nerka badanych w warunkach immersji wodnej.