Irresectable hepatoma treated by intrahepatic iodized oil doxorubicin hydrochloride: initial results.
In this study we describe the investigation and treatment of 14 patients with primary hepatocellular carcinoma. Patients were treated with intra-arterial infusion of iodized oil and doxorubicin hydrochloride. Five of these patients were alive after 1 year. Twelve patients showed a fall in alpha-fetoprotein, and in seven of these patients, the fall in alpha-fetoprotein was greater than 50%.
Kirk
S
S
Department of Surgery, University of Capetown, South Africa.
Blumgart
R
R
Craig
B
B
Rosen
A
A
Terblanche
J
J
Spence
R A
RA
D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000188:drug therapy*; D002460:Cell Line; D004261:DNA Replication / Q000187:drug effects; D004317:Doxorubicin / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007261:Infusions, Intra-Arterial; D007459:Iodized Oil / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D007482:Iothalamate Meglumine / Q000008:administration & dosage / Q000627:therapeutic use; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008297:Male; D010865:Pilot Projects; D014057:Tomography, X-Ray Computed
D007459:Iodized Oil; D004317:Doxorubicin; D007482:Iothalamate Meglumine