High amounts of glucose and insulin inhibit p-nitrophenol conjugation in mouse hepatocytes.
Bánhegyi
G
G
1st Institute of Biochemistry, Semmelweis University Medical School, Budapest, Hungary.
Puskás
R
R
Garzó
T
T
Antoni
F
F
Mandl
J
J
D000818:Animals; D001711:Biotransformation / Q000187:drug effects; D000242:Cyclic AMP / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D005215:Fasting; D005947:Glucose / Q000008:administration & dosage / Q000494:pharmacology*; D014453:Glucuronosyltransferase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D007328:Insulin / Q000008:administration & dosage / Q000494:pharmacology*; D007700:Kinetics; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D051379:Mice; D009596:Nitrophenols / Q000493:pharmacokinetics / Q000494:pharmacology*; D006005:Phosphorylases / Q000378:metabolism; D012503:Saponins / Q000494:pharmacology; D014535:Uridine Diphosphate Glucuronic Acid / Q000378:metabolism
D007328:Insulin; D009596:Nitrophenols; D012503:Saponins; D014535:Uridine Diphosphate Glucuronic Acid; D000242:Cyclic AMP; D006005:Phosphorylases; D014453:Glucuronosyltransferase; D005947:Glucose; C024836:4-nitrophenol