title: Recent study on radioiodination of [4-127I]iodoantipyrine via isotope-exchange in dry-states up-to melt.
abstract: A recent study on the radioiodination of [4-127I]iodoantipyrine with Na131I via no-carrier-added isotope exchange in dry-states up-to melt at 160 degrees C using different inorganic ammonium salts as catalyst was described at different reaction conditions of concentrations and temperatures (100-160 degrees C). A radiochemical yield (%) up to 98.5 of pure [4-131I]iodoantipyrine was obtained in melt (at 160 degrees C) using di-ammonium hydrogen orthophosphate within 2-5 min. The reaction offers a good possibility to label [4-127I]iodoantipyrine with short-lived radioiodine isotopes with no substrate decomposition.
authors.affiliation: Radioisotope Production and Labelled Compounds Department, Atomic Energy Establishment, Cairo, Egypt.
authors.forename: G
authors.initials: G
authors.lastname: el-Shaboury
authors.forename: K
authors.initials: K
authors.lastname: Farah
mesh_terms: D000983:Antipyrine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D002855:Chromatography, Thin Layer; D007457:Iodine Radioisotopes / Q000737:chemistry*; D007553:Isotope Labeling / Q000379:methods*; D010710:Phosphates / Q000737:chemistry; D013696:Temperature
chemical_list: D007457:Iodine Radioisotopes; D010710:Phosphates; C024788:ammonium phosphate; D000983:Antipyrine; C008135:iodoantipyrine