title: [The results of a controlled field trial of a dried erythrocytic immunoglobulin diagnostic agent for detecting the hepatitis A virus antigen].
abstract: The results of the controlled field trial of lyophilized erythrocytic immunoglobulin diagnosticum for the detection of hepatitis A virus antigen in the urine and feces of patients are presented. This diagnosticum was used for the study of urine and fecal samples from 225 patients (of these, 176 had hepatitis A) and 54 healthy persons in the passive hemagglutination (PHA) test. Their blood sera were studied in the PHA test (to detect HBsAg) and the radioimmunoassay (to detect anti-HAV IgM). The immunoglobulin diagnosticum under study was found to be nonspecific and faintly sensitive and, therefore, unsuitable for use in medical practice.
authors.forename: M A
authors.initials: MA
authors.lastname: Gorbunov
authors.forename: N M
authors.initials: NM
authors.lastname: Nikitiuk
authors.forename: Iu F
authors.initials: IuF
authors.lastname: Solov'ev
authors.forename: L G
authors.initials: LG
authors.lastname: Karpovich
authors.forename: T V
authors.initials: TV
authors.lastname: Kalashnikova
authors.forename: A R
authors.initials: AR
authors.lastname: Reĭzis
authors.forename: V A
authors.initials: VA
authors.lastname: Anan'ev
authors.forename: N V
authors.initials: NV
authors.lastname: Doroshenko
authors.forename: M A
authors.initials: MA
authors.lastname: Donets
authors.forename: M O
authors.initials: MO
authors.lastname: Favorov
mesh_terms: D000293:Adolescent; D000328:Adult; D000956:Antigens, Viral / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D004912:Erythrocytes / Q000276:immunology*; D005243:Feces / Q000382:microbiology; D005260:Female; D006386:Hemagglutination Tests / Q000379:methods; D006506:Hepatitis A / Q000175:diagnosis; D006507:Hepatovirus / Q000276:immunology*; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity
chemical_list: D000956:Antigens, Viral; D007075:Immunoglobulin M
vernacular_title: Rezul'taty polevogo kontroliruemogo ispytaniia diagnostikuma éritrotsitarnogo immunoglobulinovogo sukhogo dlia vyiavleniia antigena virusa gepatitia A.