[Cerebral glucose metabolism in schizophrenia. Studies using positron-emission tomography].
Several studies using positron emission tomography with 18F-fluorodeoxyglucose (18F-FDG) have revealed functional hypofrontality in schizophrenia. However, frontal hypometabolism is not consistently found and is not specific to schizophrenia. Basal ganglia glucose hypermetabolism related to neuroleptic treatment has been demonstrated. Methodological and clinical differences between studies are discussed in this paper.
M'Rabet
N
N
Service de Psychiatrie, Cliniques Universitaires de Bruxelles, Hôpital Erasme, Belgique.
Lotstra
F
F
Goldman
S
S
Delvenne
V
V
Mendlewicz
J
J
D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging / Q000378:metabolism*; D003847:Deoxyglucose / Q000031:analogs & derivatives; D005260:Female; D019788:Fluorodeoxyglucose F18; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D008297:Male; D012559:Schizophrenia / Q000378:metabolism*; D014055:Tomography, Emission-Computed
D019788:Fluorodeoxyglucose F18; D003847:Deoxyglucose; D005947:Glucose
Métabolisme cérébral du glucose dans la schizophrénie. Etudes par la tomographie à émission de positons.