title: The effect of partial coating with hydroxyapatite on bone remodeling in relation to porous-coated titanium-alloy dental implants in the dog.
abstract: For inhibition of crestal bone resorption due to stress shielding and disuse atrophy, an hydroxyapatite (HA) plasma coating was added to the coronal portion of partially porous-coated endosseous dental implants. These implants, as well as control non-HA-coated implants were placed in healed mandibular premolar extraction sites in dogs for a 72-week period of function. Histological examination showed that both implant designs became securely fixed by bone ingrowth into the porous-coated apical region of the implants. The plasma-sprayed HA coating resulted in significantly greater bone height formation and maintenance next to the coronal portion of the implant compared with non-HA-coated implants of similar design. In addition, significant resorption of the 20-to-50-microns-thick plasma-sprayed HA coating occurred over the 18-month period of function.
authors.affiliation: Faculty of Dentistry, University of Toronto, Ontario, Canada.
authors.forename: R M
authors.initials: RM
authors.lastname: Pilliar
authors.forename: D A
authors.initials: DA
authors.lastname: Deporter
authors.forename: P A
authors.initials: PA
authors.lastname: Watson
authors.forename: M
authors.initials: M
authors.lastname: Pharoah
authors.forename: M
authors.initials: M
authors.lastname: Chipman
authors.forename: N
authors.initials: N
authors.lastname: Valiquette
authors.forename: S
authors.initials: S
authors.lastname: Carter
authors.forename: K
authors.initials: K
authors.lastname: De Groot
mesh_terms: D000497:Alloys / Q000494:pharmacology*; D000704:Analysis of Variance; D000818:Animals; D016723:Bone Remodeling / Q000187:drug effects*; D003758:Dental Implantation, Endosseous; D003779:Denture Design; D004285:Dogs; D017886:Durapatite; D006882:Hydroxyapatites / Q000494:pharmacology*; D008297:Male; D008334:Mandible / Q000187:drug effects / Q000648:ultrastructure; D008422:Materials Testing; D008854:Microscopy, Electron; D016062:Porosity; D013997:Time Factors; D014025:Titanium / Q000494:pharmacology*
chemical_list: D000497:Alloys; D006882:Hydroxyapatites; C031462:titanium alloy (TiAl6V4); D017886:Durapatite; D014025:Titanium