title: Alterations in uterine contractility during the oviposition cycle in domestic hens.
abstract: 1. The potencies of several neurohypophysial hormones were examined at different times during the oviposition cycle in an in vitro fowl oxytocic assay. 2. Uterine tissues were removed 2 h before (-2h-OP), immediately after (0h-OP) and 5 h after (+5h-OP) spontaneous oviposition. In addition, uterine tissue was removed immediately after oviposition was induced, by administering prostaglandin E2 2 h before an expected oviposition (Induced-OP). 3. The rank order of oxytocic potencies for the peptides was arginine vasotocin = vasopressin greater than oxytocin greater than mesotocin. The sensitivity of the uterus to the hormones was 0h-OP = Induced-OP greater than -2h-OP = +5-OP. 4. These results suggest that uterine sensitivity to neurohypophysial hormones changes during the oviposition cycle in domestic fowls.
authors.affiliation: Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock 72205.
authors.forename: N
authors.initials: N
authors.lastname: Saito
authors.forename: T I
authors.initials: TI
authors.lastname: Koike
mesh_terms: D000818:Animals; D001127:Arginine Vasopressin / Q000494:pharmacology; D002645:Chickens / Q000502:physiology*; D046508:Culture Techniques; D015232:Dinoprostone / Q000494:pharmacology; D005260:Female; D010058:Oviposition / Q000187:drug effects / Q000502:physiology*; D010121:Oxytocin / Q000031:analogs & derivatives / Q000494:pharmacology; D014590:Uterine Contraction / Q000187:drug effects / Q000502:physiology*; D014599:Uterus / Q000187:drug effects / Q000502:physiology*; D014668:Vasotocin / Q000494:pharmacology
chemical_list: D001127:Arginine Vasopressin; C001713:mesotocin; D010121:Oxytocin; D015232:Dinoprostone; D014668:Vasotocin