title: Mammographic localization and biopsy of nonpalpable breast lesions. A 5-year study.
abstract: A malignancy rate of 24% was achieved as a result of needle localizations and biopsies of 548 nonpalpable mammographically detected breast lesions in 507 consecutive patients during a 5-year period. Malignancy was present in 74 (23.8%) of 311 irregular soft-tissue densities, in 40 (19.6%) of 204 cases with clustered microcalcifications, and in 33 cases (54.5%) when both features were present. Same-day admission and discharge were achieved in 491 patients and local anesthesia supplemented with intravenous sedation was used in 73 (74%) of the 98 patients (in 1989) by the end of the study period. Nonpalpable cancers were categorized pathologically as stage 0 in 25 patients (20.8%), stage I in 67 patients (55.8%), stage IIA in 24 patients (20.0%), and stage IIB in four patients (3.3%). The malignancy rate rose sharply from the fourth to the fifth decade.
authors.affiliation: Department of Surgery, Rhode Island Hospital, Brown University Program in Medicine, Providence 02902.
authors.forename: W R
authors.initials: WR
authors.lastname: Thompson
authors.forename: J R
authors.initials: JR
authors.lastname: Bowen
authors.forename: B A
authors.initials: BA
authors.lastname: Dorman
authors.forename: V E
authors.initials: VE
authors.lastname: Pricolo
authors.forename: T K
authors.initials: TK
authors.lastname: Shahinian
authors.forename: C H
authors.initials: CH
authors.lastname: Soderberg
mesh_terms: D001707:Biopsy, Needle / Q000379:methods; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000473:pathology; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D010173:Palpation; D012189:Retrospective Studies; D013997:Time Factors