Clinical implications of basic neuroscience research. II: NMDA receptors and neurotrophic factors.
The clinical implications of two areas of basic neuroscience research are described in this review paper. These areas include the identification of glutamate receptors on central neurons and their involvement in brain injury, and the role of nerve growth factor in the development and treatment of Alzheimer disease.
Barry
S R
SR
Department of Physical Medicine and Rehabilitation, University of Michigan School of Medicine, Ann Arbor.
D000544:Alzheimer Disease / Q000473:pathology / Q000628:therapy*; D002561:Cerebrovascular Disorders / Q000378:metabolism; D006801:Humans; D009414:Nerve Growth Factors / Q000502:physiology*; D017470:Receptors, Glutamate; D016194:Receptors, N-Methyl-D-Aspartate / Q000502:physiology*; D017981:Receptors, Neurotransmitter / Q000502:physiology*
D009414:Nerve Growth Factors; D017470:Receptors, Glutamate; D016194:Receptors, N-Methyl-D-Aspartate; D017981:Receptors, Neurotransmitter