Sarcomatous change in a teratoma after treatment of testicular carcinoma.
Treatment can transform the metastases of nonseminomatous germ cell carcinoma into histologically mature teratoma. These lesions typically have a benign clinical course. The authors present a case of leiomyosarcoma occurring within such a lesion. It arose 18 years after therapy for metastatic embryonal carcinoma of the testis and appears to have been radiation induced.
Radford
D M
DM
Department of Surgery, St. Louis University Medical Center, Missouri 63110-0250.
Johnson
F E
FE
Janney
C G
CG
D000328:Adult; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D003037:Cobalt Radioisotopes / Q000627:therapeutic use; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology*; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000532:radiotherapy; D009381:Neoplasms, Radiation-Induced / Q000473:pathology*; D012186:Retroperitoneal Neoplasms / Q000473:pathology*; D013736:Testicular Neoplasms / Q000532:radiotherapy*
D003037:Cobalt Radioisotopes