Genital carcinoma after radiotherapy for carcinoma of the cervix. Report of two cases.
Two cases of genital carcinoma were found after radiotherapy for carcinoma of the cervix. Vulval carcinoma occurred 30 years after radiation with initial symptoms of itching and whitish changes of the skin at the external genitalia. Adenocarcinoma of the endometrium occurred 9 years after radiation and diffused intra-abdominal metastasis was found surgically. The sites of second malignancies following irradiation for cervical carcinoma and the time interval between them were reviewed. The characteristics of the post-radiation vulval carcinoma and the endometrial carcinoma were discussed.
Hou
X H
XH
Department of Obstetrics and Gynecology, People's Hospital, Beijing Medical University.
Qian
H N
HN
D002288:Adenocarcinoma, Mucinous / Q000209:etiology / Q000473:pathology; D000368:Aged; D002278:Carcinoma in Situ / Q000209:etiology*; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D009381:Neoplasms, Radiation-Induced; D011878:Radiotherapy / Q000009:adverse effects*; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*; D014594:Uterine Neoplasms / Q000209:etiology / Q000473:pathology; D014846:Vulvar Neoplasms / Q000209:etiology*