The hospital management of severe migrainous headache.
In a two year period, 47 patients with migraine were hospitalized for the management of severe headache; 18 had acute migraine (duration less than 72 hours), 17 had status migrainosus (duration by definition more than 72 hours), and 12 had chronic daily headaches qualitatively of a migraine type. Treatment in all comprised cessation of all previous medication, plus one of the following: intravenous DHE, intravenous lidocaine, a combination of lidocaine + DHE, or subcutaneous sumatriptan. Improvement from DHE, lidocaine, or both was slow and often incomplete. Sumatriptan was not used in patients with chronic daily headaches; in the 8 cases of acute migraine or status migrainosus in which it was used, improvement was rapid and complete in seven.
Jauslin
P
P
Institute of Neurological Sciences, Prince Henry Hospital, Sydney, Australia.
Goadsby
P J
PJ
Lance
J W
JW
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004087:Dihydroergotamine / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007211:Indoles / Q000627:therapeutic use*; D008012:Lidocaine / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy*; D012189:Retrospective Studies; D013449:Sulfonamides / Q000627:therapeutic use*; D018170:Sumatriptan
D007211:Indoles; D013449:Sulfonamides; D004087:Dihydroergotamine; D018170:Sumatriptan; D008012:Lidocaine