title: Mucinous syringometaplasia mimicked by a clear cell hidradenoma with mucinous change.
abstract: An adnexal tumor with features of both clear cell hidradenoma and mucinous syringometaplasia is reported. The lesion occurred as a solitary, asymptomatic, slow growing nodule of 6-months duration on the anterior neck of a 55-year-old woman. Serous fluid could be expressed from a central skin opening. Histologically, there was a squamous-lined invagination with foci of mucin-laden cells. A ductal component with a variable admixture of mucinous cells merged with a nearby clear cell hidradenoma. Because clinicopathologic similarities exist between mucinous syringometaplasia and clear cell hidradenoma with mucinous change, thorough sectioning of mucinous syringometaplasia-like lesions is necessary to exclude an associated sweat gland neoplasm.
authors.affiliation: Department of Dermatology, University of Pittsburgh.
authors.forename: S J
authors.initials: SJ
authors.lastname: Hunt
authors.forename: E
authors.initials: E
authors.lastname: Abell
mesh_terms: D006607:Adenoma, Sweat Gland / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009077:Mucins; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology*; D013544:Sweat Gland Neoplasms / Q000175:diagnosis
chemical_list: D009077:Mucins