Clinical comparison of dementia in Parkinson's and Alzheimer's disease.
Neuropsychological, neuropathological and neurochemical findings show different types of dementias. Few of them have been able to confirm a division into "subcortical" and "cortical" dementia, so this concept has to be questioned. The present clinical study compared type and severity of dementia in 12 Parkinson-patients (PD) and 12 Alzheimer-patients (AD). The age-adjusted normal value differed a significantly from both patient groups. No significant difference in pattern of neuropsychological deficits between PD- and AD-patients was apparent. However, after similar duration of illness, dementia was more severe in AD- than in PD-patients.
Marschall
I
I
Neurological University Clinic, Vienna, Austria.
Dal-Bianco
P
P
Maly
J
J
Auff
E
E
Hufgard
J
J
Mraz
M
M
Deecke
L
L
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000150:complications / Q000523:psychology*; D003704:Dementia / Q000209:etiology / Q000473:pathology / Q000503:physiopathology / Q000523:psychology*; D006801:Humans; D008875:Middle Aged; D009474:Neurons / Q000502:physiology; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000150:complications / Q000523:psychology*; D012720:Severity of Illness Index; D009435:Synaptic Transmission