title: [Induction of humoral antibodies by a BHV-1 intradermal test].
abstract: An intradermal test for the diagnosis of BHV 1 (Intrakutantest Behringwerke AG) was applied to 53 nonvaccinated BHV 1-seronegative cattle aged 7 months to 8 years. Serologic blood testing performed subsequently using ELISA (Enzygnost-IBR/IPV, Behringwerke AG) and SNT revealed seroconversion in 24 of 45 animals without previous maternal antibodies. A second application of the intradermal test after these BHV 1-antibodies had declined, lead to a 'booster-effect' while a control group remained negative. Six of nine animals not affected by the first intradermal application of BHV 1-antigen, developed BHV 1-antibodies following the second intradermal test. Eight animals possessing maternal antibodies showed no serological response to the intradermal test at all. Present results strongly suggest an induction of humoral BHV 1-antibodies by the intradermal application of inactivated BHV 1. Consequently, the indirect control of BHV 1 infections, especially in cattle breeding farms, should be done exclusively by serological examination.
authors.affiliation: Staatl. Veterinäruntersuchungsamt Arnsberg.
authors.forename: R
authors.initials: R
authors.lastname: Jungblut
authors.forename: W
authors.initials: W
authors.lastname: Hopp
authors.forename: F
authors.initials: F
authors.lastname: Wessel-Ellermann
authors.forename: K H
authors.initials: KH
authors.lastname: Witte
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis*; D002417:Cattle; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D007242:Herpesvirus 1, Bovine / Q000276:immunology*; D007241:Infectious Bovine Rhinotracheitis / Q000276:immunology*; D007428:Intradermal Tests / Q000662:veterinary*; D008297:Male; D009500:Neutralization Tests
chemical_list: D000914:Antibodies, Viral
vernacular_title: Induktion humoraler Antikörper durch einen BHV 1-Intrakutantest.