title: [Search for early indications for reintubation after mechanical ventilation weaning of the newborn].
abstract: Early predictive factors for successful extubation were investigated, in order to determine the best moment for respiratory weaning of the newborn, and the risk of subsequent reintubation. PaO2/FiO2 ratio, PCO2 and respiratory rate were measured 2 h after extubation in 100 newborn infants. There was no statistically significant difference for the PaO2/FiO2 ratio and PCO2 between infants who were successfully extubated (group 1) and those who required subsequent reintubation (group 2). By contrast, the respiratory rate 2 h after extubation was significantly higher in group 2, and a respiratory rate greater than 70/min appears to be the earliest ventilatory modification predictive of the need for further mechanical ventilation before the occurrence of hypoxemia and respiratory acidosis.
authors.affiliation: Service de réanimation infantile et prématurés, CHU Saint-Jacques, Besançon, France.
authors.forename: R
authors.initials: R
authors.lastname: Destuynder
authors.forename: A
authors.initials: A
authors.lastname: Menget
authors.forename: C
authors.initials: C
authors.lastname: Fromentin
authors.forename: A
authors.initials: A
authors.lastname: Burguet
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D007442:Intubation, Intratracheal / Q000379:methods* / Q000706:statistics & numerical data; D011237:Predictive Value of Tests; D013997:Time Factors; D015300:Ventilator Weaning / Q000379:methods*
vernacular_title: Recherche de critères précoces de réintubation après sevrage de la ventilation mécanique du nouveau-né.