title: Antiviral activity of Flos verbasci infusion against influenza and Herpes simplex viruses.
abstract: The lyophilized infusion from flowers of Verbascum thapsiforme Schrad. (FVI) showed antiviral activity in in vitro studies against Fowl plague virus, several influenza A strains, influenza B strain as well as Herpes simplex virus. Influenza viruses titer decreased by 1-3 log units, while of H. simplex virus by 2.3 log. FVI has shown virucidal activity on H. simplex virus at 300 micrograms/ml, but did not inactivate influenza viruses. Phytochemical investigations of FVI have shown the presence of flavonoids, iridoids, phenolic acids, saponins, amino acids and free sugars.
authors.affiliation: Department of Virology, Medical Academy, Kraków, Poland.
authors.forename: I
authors.initials: I
authors.lastname: Zgórniak-Nowosielska
authors.forename: J
authors.initials: J
authors.lastname: Grzybek
authors.forename: N
authors.initials: N
authors.lastname: Manolova
authors.forename: J
authors.initials: J
authors.lastname: Serkedjieva
authors.forename: B
authors.initials: B
authors.lastname: Zawilińska
mesh_terms: D000818:Animals; D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification*; D002478:Cells, Cultured; D009980:Influenza A virus / Q000187:drug effects; D009975:Orthomyxoviridae / Q000187:drug effects*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D010946:Plants, Medicinal; D018139:Simplexvirus / Q000187:drug effects*; D014779:Virus Replication / Q000187:drug effects
chemical_list: D000998:Antiviral Agents; D010936:Plant Extracts