title: Relapsing hepatitis due to cytomegalovirus?
abstract: A case of agammaglobulinaemia with hyper IgM (the 'hyper-IgM syndrome') is described, in which a serological diagnosis of cytomegalovirus infection was made during repeated episodes of hepatitis. Three unrelated serological tests agreed with each other, but eventually it appeared that the reactions were non-specific. This shows the limitation of confirmation by tests which are used routinely.
authors.affiliation: Department of Virology, University of Nijmegen, The Netherlands.
authors.forename: J M
authors.initials: JM
authors.lastname: Galama
authors.forename: J W
authors.initials: JW
authors.lastname: van der Meer
authors.forename: I
authors.initials: I
authors.lastname: van Munster
authors.forename: C R
authors.initials: CR
authors.lastname: Weemaes
mesh_terms: D000328:Adult; D000361:Agammaglobulinemia / Q000150:complications / Q000276:immunology; D000914:Antibodies, Viral / Q000032:analysis; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000276:immunology; D005260:Female; D006525:Hepatitis, Viral, Human / Q000382:microbiology*; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications / Q000276:immunology; D007118:Immunoassay; D007075:Immunoglobulin M / Q000032:analysis / Q000276:immunology; D012008:Recurrence; D013577:Syndrome
chemical_list: D000914:Antibodies, Viral; D007075:Immunoglobulin M