title: Cytomegalovirus myocarditis in transplanted heart verified by endomyocardial biopsy.
abstract: Cytomegalovirus infections are common disorders after heart transplantations. Manifestation of the virus without a clinical disease is still more prevalent. Differentiation of clinical infections from cytomegalovirus activations without major pathogenetic importance issues a challenge in the follow-up of patients with cardiac transplants. The case describes a 56-year-old female patient with a multiple organ lethal infection and myocarditis due to cytomegalovirus diagnosed during life with endomyocardial biopsy.
authors.affiliation: First Department of Medicine, Helsinki University Central Hospital, Finland.
authors.forename: J
authors.initials: J
authors.lastname: Partanen
authors.forename: M S
authors.initials: MS
authors.lastname: Nieminen
authors.forename: L
authors.initials: L
authors.lastname: Krogerus
authors.forename: I
authors.initials: I
authors.lastname: Lautenschlager
authors.forename: A
authors.initials: A
authors.lastname: Geagea
authors.forename: P
authors.initials: P
authors.lastname: Aarnio
authors.forename: S
authors.initials: S
authors.lastname: Mattila
mesh_terms: D001706:Biopsy; D003586:Cytomegalovirus Infections / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*; D005260:Female; D015774:Ganciclovir / Q000008:administration & dosage / Q000627:therapeutic use; D006333:Heart Failure / Q000601:surgery; D016027:Heart Transplantation / Q000009:adverse effects* / Q000276:immunology; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D008875:Middle Aged; D009205:Myocarditis / Q000188:drug therapy / Q000209:etiology / Q000473:pathology*
chemical_list: D015774:Ganciclovir