title: Analysis of serotypes and electropherotypes of equine rotaviruses isolated in the United States.
abstract: Equine group A rotaviruses isolated over a 10-year period in New York State, New Jersey, Kentucky, and Texas were compared serotypically and electropherotypically. All isolates were determined to be serotype 3 by reaction with hyperimmune antiserum to the serotype 3 H-2 strain of equine rotavirus. All displayed RNA electrophoretic migration patterns related to that of the H-2 strain but distinct from that of serotype 5 strain H-1. A serologic survey of 184 mares in Kentucky, which was done to determine the incidence of H-1 and H-2 infections, showed geometric mean serum neutralizing titers to the H-2 strain of equine rotavirus to be significantly higher than those to the H-1 strain. These data suggest that the serotype 3 H-2 strain is the dominant equine rotavirus in Kentucky and perhaps elsewhere in the United States. We were unable to produce confirmational evidence that the H-1 strain occurs as a natural infection in the United States.
authors.affiliation: Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A&M University, College Station 77843-4467.
authors.forename: M E
authors.initials: ME
authors.lastname: Hardy
authors.forename: G N
authors.initials: GN
authors.lastname: Woode
authors.forename: Z C
authors.initials: ZC
authors.lastname: Xu
authors.forename: J D
authors.initials: JD
authors.lastname: Williams
authors.forename: M E
authors.initials: ME
authors.lastname: Conner
authors.forename: R M
authors.initials: RM
authors.lastname: Dwyer
authors.forename: D G
authors.initials: DG
authors.lastname: Powell
mesh_terms: D000818:Animals; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006734:Horse Diseases / Q000382:microbiology; D006736:Horses / Q000382:microbiology*; D011247:Pregnancy; D012367:RNA, Viral / Q000235:genetics / Q000302:isolation & purification; D012401:Rotavirus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D012400:Rotavirus Infections / Q000382:microbiology / Q000662:veterinary; D012703:Serotyping; D014481:United States
chemical_list: D012367:RNA, Viral