title: [Pain in children: the mechanisms of transmission and response].
abstract: The pain transmission pathways are briefly reviewed, emphasizing the major role the endogenous opioid system plays as a modulator of the pain. The neuroanatomic and physiologic evolution of pain, both in fetus and newborns, are also stated, as well as its relationship with clinical and hormonal response to harmful stimulus. On the whole as newborns can perceive pain preventing this with anaesthetic agents reduces the surgical stress.
authors.affiliation: Servicio de Anestesiología-Reanimación y Terapéutica del Dolor, Edifico Nen Jesus, Hospital de Sabadell, Barcelona.
authors.forename: J
authors.initials: J
authors.lastname: Marco Valls
mesh_terms: D000344:Afferent Pathways / Q000187:drug effects / Q000503:physiopathology; D000700:Analgesics / Q000494:pharmacology; D004525:Efferent Pathways / Q000187:drug effects / Q000503:physiopathology; D006801:Humans; D007231:Infant, Newborn; D009619:Nociceptors / Q000187:drug effects / Q000503:physiopathology; D010146:Pain / Q000503:physiopathology*; D009435:Synaptic Transmission / Q000187:drug effects / Q000502:physiology*
chemical_list: D000700:Analgesics
vernacular_title: Dolor en el niño: mecanismos de transmisión y respuesta.