Fermentable fibers and vitamin B12 dependency.
Addition of the fermentable fiber pectin to a B12-deficient diet accelerates development of deficiency symptoms. This appears to be the result of changes in the intestinal bacteria that bind vitamin B12, interfere with enterohepatic circulation, and accelerate depletion of this vitamin.
D000818:Animals; D004043:Dietary Fiber / Q000494:pharmacology*; D004755:Enterobacteriaceae / Q000378:metabolism; D005285:Fermentation; D010368:Pectins / Q000494:pharmacology*; D014805:Vitamin B 12 / Q000378:metabolism; D014806:Vitamin B 12 Deficiency
D004043:Dietary Fiber; D010368:Pectins; D014805:Vitamin B 12