Refinement of localization of the human genes for myeloperoxidase (MPO), protein kinase C, alpha polypeptide, PRKCA, and the DNA fragment D17S21 on chromosome 17q.
The reciprocal translocation t(2;17) (q21.2; q23.2) was used to map the human genes for myeloperoxidase (MPO), protein kinase C, alpha polypeptide, PRKCA, and the anonymous DNA fragment D17S21 more precisely on human chromosome 17q. MPO and PRKCA remain on the der(17) chromosome and therefore are assigned to 17(q21.3-q23.2) and 17(q22-q23.2), respectively. D17S21 is translocated to chromosome der(2) and by this is assigned to 17(q23.3-q24).
Latos-Bielenska
A
A
Institute of Pediatrics, Medical Academy, Poznan, Poland.
Klett
C
C
Just
W
W
Hameister
H
H
D002874:Chromosome Mapping; D002886:Chromosomes, Human, Pair 17; D015342:DNA Probes / Q000235:genetics; D005819:Genetic Markers / Q000235:genetics; D006801:Humans; D008297:Male; D009693:Nucleic Acid Hybridization; D009195:Peroxidase / Q000235:genetics*; D011493:Protein Kinase C / Q000235:genetics*; D014178:Translocation, Genetic / Q000235:genetics*
D015342:DNA Probes; D005819:Genetic Markers; D009195:Peroxidase; D011493:Protein Kinase C