Serum peptide III-procollagen and ACE in asbestos workers.
Type-III-procollagen peptide (P-III-P) concentration and angiotensin-converting-enzyme (ACE) activity were measured in the serum of asbestos workers. The subjects were classified into four groups (A, B, C, D) according to the duration of exposure (in years). A gradual increase of ACE activity in group B and P-III-P concentration in group C was found. The increase in ACE activity can be regarded as the response to the progressing inflammatory state, and the increase in P-III-P concentration may be related to the fibrosis of the lung tissue.
Owczarek
H
H
Department of Medical Analytics, Medical Academy Wroclaw, Poland.
Lewczuk
E
E
D001194:Asbestos / Q000009:adverse effects*; D001195:Asbestosis / Q000097:blood / Q000201:enzymology / Q000209:etiology; D006801:Humans; D016273:Occupational Exposure; D007703:Peptidyl-Dipeptidase A / Q000097:blood*; D011348:Procollagen N-Endopeptidase / Q000097:blood*; D011658:Pulmonary Fibrosis / Q000097:blood / Q000201:enzymology / Q000209:etiology*; D013997:Time Factors
D001194:Asbestos; D007703:Peptidyl-Dipeptidase A; D011348:Procollagen N-Endopeptidase