[Supercarcinogens and supermutagens--nitrosoalkoxyalkylamines--effective producers of nitrogen oxide].
Nitrosoalcoxyalkylamines are more efficient producers of nitrogen oxide in vivo than nitrosoalkylamines. Production of nitrogen oxide was monitored by EPR. The patterns of denitrosylation have been studied. The ability of the studied compounds to produce nitrogen oxide in vivo may be related to their carcinogenic and mutagenic action.
Vanin
A F
AF
Vedernikov
Iu P
IuP
Galagan
M E
ME
Ignatov
S M
SM
Kubrina
L N
LN
Malenkova
I V
IV
Mordvintsev
P I
PI
Kostianovskiĭ
R G
RG
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002273:Carcinogens / Q000494:pharmacology*; D002951:Citrates / Q000494:pharmacology; D004578:Electron Spin Resonance Spectroscopy; D005290:Ferric Compounds / Q000494:pharmacology; D008099:Liver / Q000737:chemistry / Q000187:drug effects; D008297:Male; D051379:Mice; D009153:Mutagens / Q000494:pharmacology*; D009589:Nitrogen Oxides / Q000032:analysis / Q000378:metabolism*; D015538:Nitrosation; D009603:Nitroso Compounds / Q000494:pharmacology*; D051381:Rats
D002273:Carcinogens; D002951:Citrates; D005290:Ferric Compounds; D009153:Mutagens; D009589:Nitrogen Oxides; D009603:Nitroso Compounds
Superkantserogeny i supermutageny--nitrozoalkoksialkilaminy--éffektivnye produtsenty okisi azota.