title: [Early identification of streptothricin group antibiotics].
abstract: Methodical approaches to detecting cultures producing streptothricins at the early stages of screening new antibiotics were developed. The approaches are based on chromatographic and electrophoretic mobility of streptothricins and the products of their hydrolysis in the extracts from agar cultures of actinomycetes. Application of the method for screening new antibiotics is illustrated with an example. Nine strains of actinomyces with broad antibacterial spectra isolated from soil samples were studied and 6 of them belonging to 4 species were shown to produce streptothricins in agar cultures. The new streptothricin-producing culture S. roseolilacinus was isolated.
authors.forename: L P
authors.initials: LP
authors.lastname: Terekhova
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Novozhenov
authors.forename: I V
authors.initials: IV
authors.lastname: Tolstykh
authors.forename: M G
authors.initials: MG
authors.lastname: Brazhnikova
mesh_terms: D006868:Hydrolysis; D013302:Streptomyces / Q000302:isolation & purification; D013309:Streptothricins / Q000032:analysis*; D013997:Time Factors
chemical_list: D013309:Streptothricins
vernacular_title: Ranniaia identifikatsiia antibiotikov gruppy streptotritsinov.