title: Evaluation of different assay techniques to assess the interaction between Leishmania major and L. infantum promastigotes and U937 cells.
abstract: Adherence of Leishmania major and L. infantum promastigotes to U937 cells was determined by microscopic observation or by using radiolabelled parasites. With both methods L. infantum showed a greater adherence. Aspecific attachment to plastic was greater for L. major. The possible implications of these findings in connection with disease pathogenesis are briefly discussed.
authors.affiliation: Institute of Microbiology, University of Torino, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Savoia
authors.forename: F
authors.initials: F
authors.lastname: Vulcano
authors.forename: S
authors.initials: S
authors.lastname: Biglino
authors.forename: M
authors.initials: M
authors.lastname: Zucca
mesh_terms: D000818:Animals; D002448:Cell Adhesion; D003124:Colorimetry; D003470:Culture Media; D018219:Histiocytoma, Benign Fibrous; D006801:Humans; D007893:Leishmania donovani / Q000254:growth & development / Q000378:metabolism*; D007895:Leishmania tropica / Q000254:growth & development / Q000378:metabolism*; D011849:Radioactive Tracers; D014407:Tumor Cells, Cultured
chemical_list: D003470:Culture Media; D011849:Radioactive Tracers