title: Surgical emergencies in liver disease.
abstract: In this chapter the surgical management of bleeding oesophageal varices, ruptured hepatocellular carcinoma and fulminant liver failure have been discussed. Bleeding oesophageal varices can usually be successfully treated with vasopressin, balloon tamponade and injection sclerotherapy. Emergency surgery should be considered if two courses of injection sclerotherapy have failed to achieve haemostasis. Stapled oesophageal transection and portosystemic shunting are currently the two most popular procedures. The former is associated with a lower morbidity and mortality as well as a lower incidence of subsequent encephalopathy. Ruptured hepatocellular carcinomas are usually associated with liver cirrhosis and impaired liver function. Selective coeliac axis cannulation followed by embolization of the hepatic artery branches supplying the tumour is an effective method of achieving haemostasis and is associated with a lower morbidity and mortality than emergency hepatic artery ligation or liver resection. If haemostasis is achieved by embolization the patient may subsequently be assessed for an elective resection of the tumour. Fulminant liver failure may be managed by supportive medical therapy or orthotopic liver transplantation. Patients whose liver failure is graded as mild (grade I) should be treated by medical therapy, whereas those with severe liver damage (grades III and IV) should be assessed for transplantation. Accurate monitoring of the patient's clinical progress and prognostic indicators are vital in deciding whether conservative treatment should be continued or liver transplantation performed.
authors.forename: B
authors.initials: B
authors.lastname: Davidson
authors.forename: R
authors.initials: R
authors.lastname: Carratta
authors.forename: F
authors.initials: F
authors.lastname: Paccione
authors.forename: N
authors.initials: N
authors.lastname: Habib
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000601:surgery; D004630:Emergencies; D004932:Esophageal and Gastric Varices / Q000601:surgery; D006471:Gastrointestinal Hemorrhage / Q000601:surgery; D006801:Humans; D008107:Liver Diseases; D008113:Liver Neoplasms / Q000601:surgery; D016031:Liver Transplantation; D011170:Portasystemic Shunt, Surgical; D012422:Rupture, Spontaneous