[Type distribution of human papilloma virus (HPV) in cervical cancer].
For analysis of the relationship between HPV type and the progress of cervical cancer, we investigated the distribution of HPV genome type in 171 cases of papilloma, cervical neoplasm early cancer and invasive cancer. The results showed that Chinese Human Papilloma Virus type 16 (CHPV16) and Chinese Human Papilloma Virus non-classified type 1 (CHPVX1) have positive rates 11.5%, 4.8%, 50.0% and 48.8%, respectively. While HPV11/HPV6 decreased with developing of cervical neoplasia. Their positive rate was 76.9%, 26.8%, 10.0% and 2.4%, respectively. There was significant difference (P less than 0.01) in X2 test for trend. It was indicated that there is a strong correlation between the CHPV16/CHPVX1 and the developing of cervical cancer.
Guo
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D000368:Aged; D005260:Female; D006801:Humans; D010212:Papilloma / Q000382:microbiology*; D027383:Papillomaviridae / Q000145:classification* / Q000302:isolation & purification; D011230:Precancerous Conditions / Q000382:microbiology; D014412:Tumor Virus Infections; D002583:Uterine Cervical Neoplasms / Q000382:microbiology*