[The effect of chaotropic anions on the course of acid hemolysis in an isotonic sugar medium].
The influence of CNS-, ClO4-, NO3-, and SO4(2-) on the kinetics of acid hemolysis of erythrocytes of man, lamb, rat and rabbit was investigated. These chaotropic anions exercised strong and specific effects on the extent and time course of acid hemolysis under such conditions. In accordance with the intensity of the exercised antihemolytic effect, these anions formed a row coinciding with the Hoffmeister's row of their chaotropic action. The results demonstrate the impact of intermolecular interactions disturbance applied mainly on the cell membrane on the mechanism of acid hemolysis.
Ivanov
I T
IT
Department of Physics and Biophysics, Medical Institute, Stara Zagora, Bulgaria.
Danailova
Iu D
IuD
D000818:Animals; D000838:Anions; D003470:Culture Media; D006461:Hemolysis / Q000187:drug effects*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D009566:Nitrates / Q000494:pharmacology*; D010472:Perchlorates / Q000494:pharmacology*; D011817:Rabbits; D051381:Rats; D012756:Sheep; D013395:Sucrose / Q000737:chemistry*; D013431:Sulfates / Q000494:pharmacology*; D013861:Thiocyanates / Q000494:pharmacology*
D000838:Anions; D003470:Culture Media; D009566:Nitrates; D010472:Perchlorates; D013431:Sulfates; D013861:Thiocyanates; D013395:Sucrose
Vliianie khaotropnykh anionov na khod kislotnogo gemoliza v izotonicheskoĭ srede sakharozy.