title: Beams eye view-based photon radiotherapy I.
abstract: Geographic miss, dosimetric miss (underdosing), and proximity of the tumor to sensitive normal tissues are some of the causes of inadequate radiation dose delivery; this is one of many causes of failure after radiotherapy. In the past decade, computerized tomography (CT)-based treatment planning has helped to overcome some of these problems. Beam's eye view (BEV)-based radiotherapy planning is an improvement over CT-based treatment planning that may further increase the therapeutic ratio. Since January 1988, we have treated 198 patients with BEV-based photon radiotherapy. About 40% of our patients treated with radical radiotherapy undergo BEV-based treatment, and about 70% of patients who undergo planning CT in the treatment position receive BEV-based radiotherapy. Our findings are as follows: (a) routine use of BEV-based RT (BEVRT) is possible in a busy radiation oncology department; (b) BEVRT improves geometric coverage of tumors; (c) BEVRT is extremely useful in the design of oblique portals; (d) time commitments for various members of the RT treatment-planning team are reasonable; (e) BEVRT helps individualize RT technique; (f) preliminary data suggest decreased acute toxicity with the use of BEVRT for prostate cancer patients. Whether these advantages will help to improve the outcome (i.e., improve local control and survival) and/or decrease the long-term toxicity is not yet known.
authors.affiliation: Michael Reese/University of Chicago, Department of Radiation and Cellular Oncology, IL 60616.
authors.forename: S
authors.initials: S
authors.lastname: Vijayakumar
authors.forename: N
authors.initials: N
authors.lastname: Low
authors.forename: G T
authors.initials: GT
authors.lastname: Chen
authors.forename: L
authors.initials: L
authors.lastname: Myrianthopoulos
authors.forename: H
authors.initials: H
authors.lastname: Culbert
authors.forename: P
authors.initials: P
authors.lastname: Chiru
authors.forename: D
authors.initials: D
authors.lastname: Spelbring
authors.forename: A
authors.initials: A
authors.lastname: Awan
authors.forename: I
authors.initials: I
authors.lastname: Rosenberg
authors.forename: H
authors.initials: H
authors.lastname: Halpern
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy; D002289:Carcinoma, Non-Small-Cell Lung / Q000532:radiotherapy; D002985:Clinical Protocols; D006801:Humans; D008175:Lung Neoplasms / Q000532:radiotherapy; D009367:Neoplasm Staging; D009369:Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D011878:Radiotherapy / Q000379:methods; D011880:Radiotherapy Planning, Computer-Assisted; D014057:Tomography, X-Ray Computed