[Familial spastic spinal paralysis--clinical spectrum and differential diagnostic considerations].
The familial spastic paraplegia is a rare disorder of the cerebral nervous system characterized by a slowly progressive spasticity of the lower limbs with early or late onset. There are pure and complicated forms. The disease is inherited by an autosomal dominant mode and a recessive one. In this study 6 patients out of 5 families are presented. The clinical variety, genetic aspects, electrophysiological results and differential diagnosis are discussed.
Klemm
E
E
Neurologische Universitätsklinik Bonn.
Tackmann
W
W
D000328:Adult; D003937:Diagnosis, Differential; D004569:Electroencephalography; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology; D005074:Evoked Potentials, Visual / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009046:Motor Neurons / Q000502:physiology; D009134:Muscular Atrophy, Spinal / Q000175:diagnosis / Q000235:genetics* / Q000503:physiopathology; D009460:Neurologic Examination; D010525:Peripheral Nerves / Q000503:physiopathology; D011930:Reaction Time / Q000502:physiology; D015419:Spastic Paraplegia, Hereditary / Q000175:diagnosis / Q000235:genetics* / Q000503:physiopathology; D009435:Synaptic Transmission / Q000502:physiology
Familiäre spastische Spinalparalyse--Klinisches Spektrum und differentialdiagnostische Erwägungen.