[Contents of prostaglandins E2 and F2alpha and cAMP in the endometrium of women with habitual abortion during late pregnancy terms].
Measurements of prostaglandins E2 and F2 alpha in the endometrium of 35 women of a reproductive age, suffering from habitual abortions in late pregnancy terms, have shown elevation of these prostaglandin levels in the secretory phase as against the reference group and their normal values during the proliferative phase. It is possible, that disordered prostaglandin synthesis in the endometrium, manifesting in pregnancy, is one of the causes of habitual abortions. cAMP levels were somewhat decreased in the secretory phase in this patient population; this permits a hypothesis on disorders in the adenylate cyclase system.
Goncharova
V N
VN
Morozova
M S
MS
Murashko
L E
LE
Sidel'nikova
V M
VM
Malysheva
V A
VA
Zaĭtseva
T S
TS
D000026:Abortion, Habitual / Q000201:enzymology / Q000209:etiology*; D000262:Adenylyl Cyclases / Q000378:metabolism; D000328:Adult; D000242:Cyclic AMP / Q000032:analysis*; D015237:Dinoprost / Q000032:analysis*; D015232:Dinoprostone / Q000032:analysis*; D004717:Endometrium / Q000737:chemistry*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third
D015237:Dinoprost; D000242:Cyclic AMP; D000262:Adenylyl Cyclases; D015232:Dinoprostone
Soderzhanie prostaglandinov E2 i F2 alfa i tsAMF v éndometrii zhenshchin, stradaiushchikh privychnym nevynashivaniem beremenosti pozdnikh srokov.