Nitrite activates the transcription of the Pseudomonas aeruginosa nitrite reductase and cytochrome c-551 operon under anaerobic conditions.
The transcription of the Pseudomonas aeruginosa denAB operon, which consists of the nitrite reductase and cytochrome c-551 genes, is induced under anaerobic conditions. However, under anaerobic non-denitrifying conditions (anaerobic growth on arginine), the promoter activity of the operon was approximately one-fifth of that under anaerobic denitrifying conditions (anaerobic growth in the presence of nitrite or nitrate). This result clearly demonstrates that the presence of nitrite or nitrate activates the transcription of P. aeruginosa denAB operon under anaerobic conditions.
Arai
H
H
Department of Agricultural Chemistry, University of Tokyo, Japan.
Igarashi
Y
Y
Kodama
T
T
D000693:Anaerobiosis; D001120:Arginine / Q000494:pharmacology; D001426:Bacterial Proteins; D003574:Cytochrome c Group / Q000235:genetics*; D015964:Gene Expression Regulation, Bacterial / Q000187:drug effects; D050901:Nitrate Reductase; D009565:Nitrate Reductases / Q000235:genetics*; D009566:Nitrates / Q000494:pharmacology; D009573:Nitrites / Q000494:pharmacology*; D009876:Operon / Q000235:genetics; D011401:Promoter Regions, Genetic / Q000187:drug effects; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000201:enzymology / Q000235:genetics*; D014158:Transcription, Genetic / Q000187:drug effects*
D001426:Bacterial Proteins; D003574:Cytochrome c Group; D009566:Nitrates; D009573:Nitrites; C017167:cytochrome C(551); D001120:Arginine; D009565:Nitrate Reductases; D050901:Nitrate Reductase