[Controversial aspects of verrucous carcinoma of the larynx: viral etiology, diagnosis and treatment].
Verrucous carcinoma is a clinical and pathological entity which was recognized only in recent years. The laryngologist and pathologist must cooperate closely to formulate a correct diagnosis, because the microscopical findings may not show cytological criteria for malignancy, whereas the clinical behaviour is locally invasive. Suitable treatment remains controversial, as radiotherapy does not only control the tumour but may be followed by anaplastic transformation. There is increasing evidence of human papillomaviruses as etiologic agents, although further studies to determine their precise role in carcinogenesis are needed.
Esteban Ortega
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Servicio de Otorrinolaringología, Ciudad Sanitaria Virgen de las Nieves, Granada.
Concha López
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D002291:Carcinoma, Papillary / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D003937:Diagnosis, Differential; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D007830:Larynx / Q000473:pathology; D027383:Papillomaviridae; D014412:Tumor Virus Infections / Q000175:diagnosis / Q000473:pathology / Q000628:therapy
Aspectos controvertidos del carcinoma verrucoso de laringe: etiología viral, diagnóstico y tratamiento.