[Polyneuropathy caused by ethylene oxide. Report of a case with clinical, electrophysiological and histopathological studies].
A man who worked as an operator in a factory of sterilization of heat-sensitive materials has been exposed to ethylene oxide for seven years. He developed a mild sensori-motor polyneuropathy. The electromyography and nerve condition studies showed an axonal degenerative type of neuropathy. The sural nerve biopsy revealed mild loss of myelinated fibers, some fibers with axonal degeneration, some clusters of regeneration and few rows of myelin ovoids in the teased nerve fiber preparation. This is the first report of ethylene-oxide polyneuropathy in Brazil.
De Freitas
M R
MR
Departamentos de Medicina Clínica, Faculdade de Medicina, Universidade Federal Fluminense, Brasil.
Nascimento
O J
OJ
Chimelli
L
L
D000328:Adult; D001706:Biopsy; D002908:Chronic Disease; D004576:Electromyography; D004594:Electrophysiology; D005027:Ethylene Oxide / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009410:Nerve Degeneration; D009413:Nerve Fibers, Myelinated / Q000187:drug effects* / Q000473:pathology / Q000502:physiology; D009784:Occupational Diseases / Q000139:chemically induced* / Q000473:pathology; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000473:pathology; D013497:Sural Nerve / Q000473:pathology
D005027:Ethylene Oxide
Polineuropatia devida ao óxido de etileno. Registro de caso com estudo clinico, eletrofisiológico e histopatológico.