[Neuropeptide factors of pathogenesis of brain-related motor disorders].
Overall 136 patients with cerebral tumors, sequels of craniocerebral injury and brain strokes with motor disorders of varying intensity were examined. Factors of the peptide nature, provoking postural asymmetry of the homolateral hind limb in an experimental animal were detected in the blood and CSF of the overwhelming majority of the patients. Provided the compensatory process runs a favorable course (recovery of motor functions), the neuropeptide factors are inactivated with inactivating substances. The data obtained attest to the advisability of further studies into the activity and nature of the factors of postural asymmetry in patients with cerebral motor disorders with a purpose of elaborating new methods of treatment and rehabilitation.
Makarov
A Iu
AIu
Vartanian
G A
GA
Pomnikov
V G
VG
Cherniaev
S G
SG
Shatik
S V
SV
Tokarev
A V
AV
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001921:Brain / Q000503:physiopathology*; D001930:Brain Injuries / Q000150:complications* / Q000503:physiopathology; D001932:Brain Neoplasms / Q000150:complications* / Q000503:physiopathology; D002544:Cerebral Infarction / Q000150:complications* / Q000503:physiopathology; D004195:Disease Models, Animal; D006429:Hemiplegia / Q000209:etiology*; D006614:Hindlimb / Q000294:innervation; D006801:Humans; D007866:Leg / Q000294:innervation*; D008875:Middle Aged; D009123:Muscle Hypotonia / Q000209:etiology*; D009132:Muscles / Q000294:innervation* / Q000503:physiopathology; D009842:Oligopeptides / Q000502:physiology*; D051381:Rats
D009842:Oligopeptides
Neĭropeptidnye faktory patogeneza tserebral'nykh dvigatel'nykh rasstroĭstv.