[Kinetic methods of reverse mechanism functions of receptor domain Na+- and K+-channels].
Complete kinetic diagrams of the gate mechanisms of Na(+)- and K(+)-channels of receptor domains were examined. Analysis of various states of gate mechanisms of these channels allow to reveal the fundamental characteristics of Na(+)- and K(+)-channels of receptor domains which can underlie the molecular mechanisms of a number of processes dealing with the functioning of receptor domains. Taking into account these characteristics of Na(+)- and K(+)-channels of receptor domains, the molecular mechanisms of generation and spreading of the action potential and the molecular mechanisms of synaptic transmission, in chemical, and electrical synapses, was proposed. A possible role of receptor domains in the processes of cell differentiation, proliferation and carcinogenesis are also discussed.
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D000200:Action Potentials; D001665:Binding Sites; D015640:Ion Channel Gating; D007700:Kinetics; D015221:Potassium Channels / Q000378:metabolism* / Q000502:physiology; D015222:Sodium Channels / Q000378:metabolism* / Q000502:physiology
D015221:Potassium Channels; D015222:Sodium Channels
Kineticheskie skhemy raboty vorotnykh mekhanizmov Na+- i K+-kanalov reseptornykh domenov.