title: A case of clozapine-induced neuroleptic malignant syndrome.
abstract: The treatment of psychotic symptoms in patients with a previous history of neuroleptic malignant syndrome (NMS) remains a dilemma. The authors describe a case in which clozapine caused NMS in a schizophrenic man who had previously experienced NMS during treatment with various antipsychotics. To their knowledge, this is the first report of "classical" NMS caused by clozapine alone.
authors.affiliation: Department of Psychiatry, University of Iowa College of Medicine, Iowa City 52242.
authors.forename: D D
authors.initials: DD
authors.lastname: Miller
authors.forename: M J
authors.initials: MJ
authors.lastname: Sharafuddin
authors.forename: R G
authors.initials: RG
authors.lastname: Kathol
mesh_terms: D014150:Antipsychotic Agents / Q000009:adverse effects; D003024:Clozapine / Q000009:adverse effects*; D003620:Dantrolene / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009459:Neuroleptic Malignant Syndrome / Q000188:drug therapy / Q000209:etiology*; D012560:Schizophrenia, Catatonic / Q000188:drug therapy* / Q000523:psychology
chemical_list: D014150:Antipsychotic Agents; D003620:Dantrolene; D003024:Clozapine