Membrane ATPase, erythrocyte sodium and potassium in haemodialysis patients.
This study was undertaken to evaluate the effect of chronic renal failure as well as dialysate sodium concentration during haemodialysis on membrane ATPase activity and erythrocyte sodium and potassium concentration. Intracellular Na and K were not changed in patients when compared to normal subjects. There was, however, a significant decrease of Na-K-ATPase activity in patients versus controls. Erythrocyte sodium increased during haemodialysis with low and normal sodium dialysate. The present results suggest that sodium dialysate concentration has an influence on the intracellular cationic homeostasis.
Solski
J
J
Department of Nephrology, Academy of Medicine, Lublin, Poland.
Ksiazek
A
A
Szymonik-Lesiuk
S
S
Marzec
Z
Z
D000251:Adenosine Triphosphatases / Q000097:blood*; D000328:Adult; D015314:Dialysis Solutions; D004910:Erythrocyte Membrane / Q000201:enzymology*; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000628:therapy*; D008297:Male; D011188:Potassium / Q000097:blood*; D006435:Renal Dialysis; D012964:Sodium / Q000097:blood*; D000254:Sodium-Potassium-Exchanging ATPase / Q000097:blood
D015314:Dialysis Solutions; D012964:Sodium; D000251:Adenosine Triphosphatases; C030704:magnesium sodium potassium ATPase; D000254:Sodium-Potassium-Exchanging ATPase; D011188:Potassium