Congenital gliosarcoma; so-called sarcoglioma.
A mixed glioma and sarcoma in a 3-month-old infant is presented as a rare case of gliosarcoma with a good response to treatment. This congenital case is quite different from those in adults: the tumor cells were mainly composed of sarcomatous elements; glial components were not anaplastic without obvious endothelial hyperplasia, but presented as reticulin-free islands, mimicking a reactive glioma in a sarcoma. It may be termed "sarcoglioma" to distinguish from a classic gliosarcoma. The origin of the rare mixed tumor may be related to a dysgenesis of both mesenchymal and glial elements.
Ono
N
N
Department of Neurosurgery, Gunma University School of Medicine, Japan.
Nakamura
M
M
Inoue
H K
HK
Tamura
M
M
Murata
M
M
D001479:Basal Ganglia / Q000473:pathology; D001480:Basal Ganglia Diseases / Q000473:pathology / Q000601:surgery*; D001932:Brain Neoplasms / Q000151:congenital* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D005260:Female; D005500:Follow-Up Studies; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D018316:Gliosarcoma / Q000151:congenital* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D008854:Microscopy, Electron; D010296:Parietal Lobe / Q000473:pathology / Q000601:surgery*; D013702:Temporal Lobe / Q000473:pathology / Q000601:surgery*
D005904:Glial Fibrillary Acidic Protein