[Fatal cytomegalovirus pneumonia in a non-immunodeficient adult. Diagnostic contribution of in situ hybridization].
A case of fatal cytomegalovirus pneumonia in a non-immunocompromised 65-year old man is reported. The patient presented with symptoms of a lower respiratory tract infection. The diagnosis of cytomegalovirus pneumonia was made after histopathological examination of the open lung biopsy. Confirmation of cytomegalovirus infection was made with in situ DNA Hybridization. The outcome was rapidly fatal. This case demonstrates the value of DNA probe analysis for diagnosis. This case is also unusual in that a non-immunocompromised adult had severe evolution of cytomegalovirus infection.
Joundi
A
A
Laboratoire Central d'Anatomie et Cytologie Pathologiques, Centre Hospitalier Régional et Universitaire de Reims, Hôpital Robert-Debré.
Caulet
T
T
Mehaut
S
S
Bakhtiari
P
P
Carquin
J
J
D000368:Aged; D001706:Biopsy; D003586:Cytomegalovirus Infections / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D004279:DNA, Viral / Q000032:analysis*; D006801:Humans; D007108:Immune Tolerance; D008297:Male; D009693:Nucleic Acid Hybridization; D011024:Pneumonia, Viral / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology
D004279:DNA, Viral
Pneumopathie fatale à CMV chez un adulte non-immuno-déprimé. Apport de l'hybridation in situ au diagnostic.