The effect of partial coating with hydroxyapatite on bone remodeling in relation to porous-coated titanium-alloy dental implants in the dog.
For inhibition of crestal bone resorption due to stress shielding and disuse atrophy, an hydroxyapatite (HA) plasma coating was added to the coronal portion of partially porous-coated endosseous dental implants. These implants, as well as control non-HA-coated implants were placed in healed mandibular premolar extraction sites in dogs for a 72-week period of function. Histological examination showed that both implant designs became securely fixed by bone ingrowth into the porous-coated apical region of the implants. The plasma-sprayed HA coating resulted in significantly greater bone height formation and maintenance next to the coronal portion of the implant compared with non-HA-coated implants of similar design. In addition, significant resorption of the 20-to-50-microns-thick plasma-sprayed HA coating occurred over the 18-month period of function.
Pilliar
R M
RM
Faculty of Dentistry, University of Toronto, Ontario, Canada.
Deporter
D A
DA
Watson
P A
PA
Pharoah
M
M
Chipman
M
M
Valiquette
N
N
Carter
S
S
De Groot
K
K
D000497:Alloys / Q000494:pharmacology*; D000704:Analysis of Variance; D000818:Animals; D016723:Bone Remodeling / Q000187:drug effects*; D003758:Dental Implantation, Endosseous; D003779:Denture Design; D004285:Dogs; D017886:Durapatite; D006882:Hydroxyapatites / Q000494:pharmacology*; D008297:Male; D008334:Mandible / Q000187:drug effects / Q000648:ultrastructure; D008422:Materials Testing; D008854:Microscopy, Electron; D016062:Porosity; D013997:Time Factors; D014025:Titanium / Q000494:pharmacology*
D000497:Alloys; D006882:Hydroxyapatites; C031462:titanium alloy (TiAl6V4); D017886:Durapatite; D014025:Titanium