Partial hydatidiform mole with subsequent trophoblastic tumor; a case report.
A case of partial hydatidiform mole revealed by genetic marker analysis one maternal and two paternal chromosome complements. Levels of serum human chorionic gonadotropin were persistently elevated during follow-up. Avillous curettage specimens prior to chemotherapy were morphologically suspicious for gestational choriocarcinoma. It is still uncertain whether the risk for gestational choriocarcinoma preceded by partial mole exceeds the risk related to non-molar abortions. Careful follow-up with serial serum human chorionic gonadotropin levels is required to detect persistent disease.
Vejerslev
L O
LO
Department of Medical Genetics, John F. Kennedy Institute, Glostrup/Copenhagen, Denmark.
Larsen
G
G
Jacobsen
M
M
D000328:Adult; D002822:Choriocarcinoma / Q000175:diagnosis / Q000473:pathology; D006063:Chorionic Gonadotropin / Q000378:metabolism; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D014328:Trophoblastic Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D014594:Uterine Neoplasms / Q000175:diagnosis*
D006063:Chorionic Gonadotropin