Maintaining integrity and credibility in industry-sponsored clinical research.
There have been recent, heightened concerns about the integrity and credibility of industry-sponsored clinical research. While attributable to a variety of factors, the potential consequences are a decrease in the ability of the biomedical research enterprise to produce innovative methods for the diagnosis and treatment of disease, with possible adverse implications for the health and well-being of the public. A specific example of a recent industry-sponsored clinical trial is presented as an approach to attempt to avoid any suggestion of fraud, error, or biased interpretation, in a way in which the integrity of the process will not be called into question and the credibility of the results will be maximized.
Schwarz
R P
RP
Sterling Research Group, Malvern, Pennsylvania 19355.
D002316:Cardiotonic Agents / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D004345:Drug Industry; D006333:Heart Failure / Q000188:drug therapy / Q000401:mortality; D006801:Humans; D020105:Milrinone; D011446:Prospective Studies; D011728:Pyridones / Q000627:therapeutic use; D011785:Quality Assurance, Health Care; D012109:Research Support as Topic; D015871:Scientific Misconduct; D015996:Survival Rate
D002316:Cardiotonic Agents; D011728:Pyridones; D020105:Milrinone