title: Hepatic and renal phosphomonoesterases and adenosine triphosphatases in chronic hyperprolactinaemic rats.
abstract: Influence of hyperprolactinaemia, induced endogenously by anterior pituitary transplantation on rat hepatic and renal cortical and medullary phosphomonoesterases and adenosine triphosphatases (ATPases) has been investigated. Although prolactin has a stimulatory effect on phosphomonoesterases and ATPases, it exhibits a specific and temporal influence on each subtype of hepatic and renal ATPases and phosphomonoesterases at different durations of pituitary transplantation. The specific activities of alkaline phosphatase and Na(+)-K+ dependent ATPases are activated in all the regions of different durations of experimentation. However, acid phosphatases, Ca2+ and Mg2+ dependent ATPases exhibit a differential response to prolactin in renal cortex, medulla and liver. Direct influence of prolactin on hepatic and renal phosphomonoesterases and ATPases is thus suggested.
authors.affiliation: Department of Endocrinology, Dr A.L.M. Post Graduate Institute of Basic Medical Sciences, Taramani, Madras, India.
authors.forename: T M
authors.initials: TM
authors.lastname: Kumari
authors.forename: P
authors.initials: P
authors.lastname: Govindarajulu
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism*; D000818:Animals; D005260:Female; D006966:Hyperprolactinemia / Q000201:enzymology*; D007668:Kidney / Q000201:enzymology*; D008099:Liver / Q000201:enzymology*; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D010744:Phosphoric Monoester Hydrolases; D000251:Adenosine Triphosphatases