title: Phagocytosis and adhesiveness of peripheral blood polymorphonuclear leukocytes in patients with rapidly progressive periodontitis.
abstract: Phagocytosis and adhesiveness of peripheral blood polymorphonuclear leukocytes were studied in patients diagnosed with generalized rapidly progressive (form A) periodontitis. All patients belonged to a single family and were first degree relatives. In the patients' leukocytes there was a statistically significant reduction in phagocytic index and adhesiveness, in comparison with leukocytes from controls. However, adhesiveness approached control values in the presence of autologous serum, thus implying that serologic factors may enhance this function in patients with this type of periodontitis.
authors.affiliation: Department of Microbiology, University of Granada, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Gutiérrez
authors.forename: A
authors.initials: A
authors.lastname: Cutando
authors.forename: A M
authors.initials: AM
authors.lastname: Castillo
authors.forename: J
authors.initials: J
authors.lastname: Liébana
authors.forename: P
authors.initials: P
authors.lastname: Baca
authors.forename: J C
authors.initials: JC
authors.lastname: Llodra
mesh_terms: D000328:Adult; D001439:Bacteroides / Q000302:isolation & purification; D002448:Cell Adhesion / Q000502:physiology; D002648:Child; D003774:Dental Plaque Index; D005260:Female; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000502:physiology*; D010512:Periodontal Index; D010518:Periodontitis / Q000097:blood / Q000235:genetics* / Q000382:microbiology / Q000473:pathology; D010587:Phagocytosis / Q000502:physiology*; D016966:Porphyromonas gingivalis / Q000302:isolation & purification; D013291:Streptococcus / Q000302:isolation & purification