[Age-related changes in the dipeptide hydrolase activity of different sections of the small intestine in rats in response to hydrocortisone administration].
The glycyl-L-leucinedipeptidehydrolase activity in different portions of the small intestine after hydrocortisone administration on the 1st, 5th, 10th, 16th, 30th day of life was studied in rats. The enzyme was mainly localized in distal portion of the small intestine for the first two weeks. The maximal reactivity of the enzyme-synthetizing system was shown after a single hydrocortisone injection during this period in proximal portion. The enzyme distribution along the small intestine became even in the end of the experimental period. The response to the hormone administration was practically absent from the 16th day of suckling life.
Rakhimov
K R
KR
Shinder
D A
DA
Likhovid
L V
LV
D000375:Aging / Q000187:drug effects* / Q000378:metabolism; D000818:Animals; D000831:Animals, Newborn; D004150:Dipeptidases / Q000187:drug effects* / Q000378:metabolism; D006854:Hydrocortisone / Q000494:pharmacology*; D007421:Intestine, Small / Q000187:drug effects* / Q000201:enzymology / Q000254:growth & development; D051381:Rats; D011919:Rats, Inbred Strains
D004150:Dipeptidases; C020825:cytosol non-specific dipeptidase; D006854:Hydrocortisone
Vozrastzavisimye izmeneniia dipeptidgidrolaznoĭ aktivnosti razlichnykh otdelov tonkoĭ kishki krys v otvet na vvedenie gidrokortizona.