Epstein-Barr virus infection in carcinoma of the salivary gland.
Undifferentiated carcinoma of the parotid gland contains clonal Epstein-Barr virus episomes without ladder arrays of restriction enzyme fragments representing virion DNA. Analysis of Epstein-Barr virus transcription in situ in parotid carcinoma specimens revealed that the EBER RNAs, latent membrane protein mRNA, and the BamHI-A rightward reading frame, BARF0, are expressed in the malignant epithelial cells.
Raab-Traub
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N
Department of Microbiology and Immunology, University of North Carolina, Chapel Hill 27599-7295.
Rajadurai
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P
Flynn
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Lanier
A P
AP
D000413:Alaska; D002277:Carcinoma / Q000382:microbiology* / Q000473:pathology; D004279:DNA, Viral / Q000235:genetics / Q000302:isolation & purification*; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D004930:Inuit; D010307:Parotid Neoplasms / Q000382:microbiology* / Q000473:pathology; D015347:RNA Probes; D012367:RNA, Viral / Q000235:genetics / Q000302:isolation & purification; D015183:Restriction Mapping; D014158:Transcription, Genetic; D014771:Virion / Q000235:genetics / Q000302:isolation & purification*
D004279:DNA, Viral; D015347:RNA Probes; D012367:RNA, Viral