Evaluation of automated enzyme immunoassays for several markers for hepatitis A and B using the Abbott IMx analyser.
The analytical performances of the Abbott IMx for the detection of several markers of hepatitis A and B (HBs Ag, anti-HBc, IgM anti-HBc, IgM anti-HAV) were evaluated. The intra-assay and the inter-assay coefficients of variation were below 5 and 10% respectively. We obtained results comparable with our routine methods, except for sera containing rheumatoid factor which gave false positive reactions with the IMx HBs Ag.
Fayol
V
V
Centre de Radioanalyse, Institut Pasteur, Lyon, France.
Ville
G
G
D000914:Antibodies, Viral / Q000097:blood; D015415:Biomarkers; D005069:Evaluation Studies as Topic; D005189:False Positive Reactions; D006506:Hepatitis A / Q000175:diagnosis* / Q000276:immunology; D006509:Hepatitis B / Q000175:diagnosis* / Q000276:immunology; D006510:Hepatitis B Antibodies / Q000097:blood; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006507:Hepatovirus / Q000276:immunology; D006801:Humans; D007124:Immunoenzyme Techniques / Q000295:instrumentation*; D012217:Rheumatoid Factor / Q000097:blood
D000914:Antibodies, Viral; D015415:Biomarkers; D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D012217:Rheumatoid Factor