[The formation of the enzyme systems of the initial and final stages of protein hydrolysis in rat postnatal ontogeny].
Proteolytic activity of the stomach and pancreas as well as glycyl-L-leucin-dipeptide-hydrolase activity of the small intestine after introduction of hydrocortisone on the 1-, 5-, 10-, 16- and 30th days of life was studied in rats. The enzyme system sensitivity responsible for protein hydrolysis was shown to be age-dependent on the hormone administration. The peculiarities of the stomach, pancreas and small intestine responses to the hormone administration was found: the enzyme system inducibility of the pancreas was significantly higher than that of the stomach and the small intestine during the whole suckling period.
Rakhimov
K R
KR
Likhovid
L V
LV
Shinder
D A
DA
D000375:Aging / Q000187:drug effects / Q000378:metabolism*; D000818:Animals; D000831:Animals, Newborn; D000833:Animals, Suckling; D006854:Hydrocortisone / Q000494:pharmacology; D006868:Hydrolysis / Q000187:drug effects; D007421:Intestine, Small / Q000187:drug effects / Q000201:enzymology; D010179:Pancreas / Q000187:drug effects / Q000201:enzymology; D010447:Peptide Hydrolases / Q000187:drug effects / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013270:Stomach / Q000187:drug effects / Q000201:enzymology; D013997:Time Factors
D010447:Peptide Hydrolases; D006854:Hydrocortisone
Formirovanie fermentnykh sistem nachal'nogo i zakliuchitel'nogo étapov gidroliza belkov v postnatal'nom ontogeneze krys.