Expression of Na,K-ATPase isoforms in human heart.
The expression pattern of the multiple isoforms of Na,K-ATPase was examined in the human heart. Isoform specific oligonucleotide probes for the alpha 1, alpha 2, alpha 3 and beta 1 subunits were used to probe Northern blots. The adult human ventricle expresses mRNAs for all three alpha subunit isoforms in addition to beta 1 subunit mRNA.
Shamraj
O I
OI
Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati, College of Medicine, Ohio 45267-0524.
Melvin
D
D
Lingrel
J B
JB
D000328:Adult; D001483:Base Sequence; D015152:Blotting, Northern; D002648:Child; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000235:genetics*; D008297:Male; D008969:Molecular Sequence Data; D009206:Myocardium / Q000201:enzymology*; D015345:Oligonucleotide Probes; D012333:RNA, Messenger / Q000235:genetics / Q000302:isolation & purification; D000254:Sodium-Potassium-Exchanging ATPase / Q000235:genetics*
D007527:Isoenzymes; D015345:Oligonucleotide Probes; D012333:RNA, Messenger; D000254:Sodium-Potassium-Exchanging ATPase