[Clinical and consequence study on 51 cases of hepatitis C].
All the 51 patients had history of plasma donation before onset of the illness. All had no evidences of recent infection with following viruses: HAV, HBV, CMV and EBV and were confirmed recently as hepatitis C by the Chiron C-100 EIA test. The incubation period was 35 to 90 days, with an average of 57.9 +/- 19.8 days. The ratio of icteric to anicteric was 1.0:1.55. Only a few cases had fever in the acute phase (13.7%). 36 cases showed acute onset of illness; 15 cases, however, had ALT elevation before the onset. 33 cases became chronic hepatitis after 1 year (64.7%), 14 out of the 33 cases had persistently abnormal ALT and 19 cases showed repeated elevation of ALT. The chronicity rate in 2 years was 38.6%. These results indicate that hepatitis C has the features of high chronicity rate and prolonged clinical course.
Chen
Z
Z
Hebei Provincial Medical Staff College, Baoding.
Wang
S Y
SY
Wang
Z G
ZG
D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D001782:Blood Donors; D005260:Female; D016174:Hepacivirus / Q000302:isolation & purification; D006526:Hepatitis C / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010956:Plasmapheresis / Q000009:adverse effects*; D011379:Prognosis
D000914:Antibodies, Viral