[Substance produced by Klebsiella pneumoniae with protects it from the bactericidal effect of normal human serum].
A Klebsiella pneumoniae culture in Fouad's chemically defined medium, which was grown from 18 to 24 hours at 37 degrees C was prepared. Bacterial cells were eliminated by centrifugation and the supernatant was sterilized by Millipore membrane filtration. A protective activity against normal human serum bactericidal effect on K. pneumoniae K-9 and K-13 was ascribed to sterile filtrate. The protective filtrate seems to be a high molecular weight substance.
Rodas-Suárez
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Departamento de Microbiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, México, D.F.
Martínez-Ramos
A
A
D001685:Biological Factors / Q000302:isolation & purification* / Q000494:pharmacology; D001770:Blood Bactericidal Activity / Q000187:drug effects*; D017077:Culture Media, Conditioned / Q000737:chemistry; D003956:Dialysis; D006801:Humans; D007711:Klebsiella pneumoniae / Q000254:growth & development / Q000378:metabolism*; D014462:Ultrafiltration
D001685:Biological Factors; D017077:Culture Media, Conditioned
Substancia producida por Klebsiella pneumoniae que la protege del efecto bactericida del suero humano normal.