[Collagenase of human leukocytes. Its characteristics, function and regulatory mechanisms].
The characteristics of the human neutrophil collagenase and intracellular and extracellular mechanism regulating this enzyme were given. There were presented molecular basis collagenase latent state , activation of latent enzyme form through the system dependent on free oxygen radicals and the role of glutathione peroxidase in the regulation of the activity of the human leukocyte collagenase.
Grabowska-Bochenek
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R
Katedra i Zakład Biochemii i Chemii Slaskiej Akademii Medycznej w Katowicach.
Drózdz
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M
D001808:Blood Vessels / Q000378:metabolism*; D003094:Collagen / Q000378:metabolism*; D004789:Enzyme Activation / Q000502:physiology; D005609:Free Radicals; D005978:Glutathione / Q000502:physiology; D005979:Glutathione Peroxidase / Q000502:physiology; D006801:Humans; D003012:Microbial Collagenase / Q000037:antagonists & inhibitors / Q000097:blood* / Q000502:physiology; D009504:Neutrophils / Q000201:enzymology*; D013482:Superoxide Dismutase / Q000502:physiology; D013481:Superoxides / Q000097:blood
D005609:Free Radicals; D013481:Superoxides; D003094:Collagen; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D003012:Microbial Collagenase; D005978:Glutathione
Kolagenaza ludzkich leukocytoów. Charakterystyka, funkcja i mechanizmy regulacyjne.