Overview: subunit diversity in the Na,K-ATPase.
The pioneering work on the Na,K-ATPase was dominated by the concept that this enzyme was essentially the same in all tissues and organisms. Now, with the development of new molecular and immunological techniques, the Na,K-ATPase is found to be composed of several clearly different subunit types. This brief update focuses on the identification of subunits and recent ideas about their functional differences.
Sweadner
K J
KJ
Neurosurgical Research, Massachusetts General Hospital, Boston 02114.
D000818:Animals; D015971:Gene Expression Regulation, Enzymologic / Q000502:physiology; D006801:Humans; D007527:Isoenzymes / Q000032:analysis* / Q000235:genetics / Q000502:physiology; D015394:Molecular Structure; D000254:Sodium-Potassium-Exchanging ATPase / Q000032:analysis* / Q000235:genetics / Q000502:physiology
D007527:Isoenzymes; D000254:Sodium-Potassium-Exchanging ATPase