title: The role of polyglycolic acid rods in the regeneration of cartilage from perichondrium in rabbits.
abstract: The role of polyglycolic acid (PGA) rods in the regeneration of cartilage from perichondrium was investigated in 12 growing rabbits. The fifth rib cartilage was resected subperichondrially from both sides. A 10 X 1.5 mm self-reinforced polyglycolic acid (SR-PGA) rod was inserted on one side to replace the resected cartilage and the retained perichondrium was sutured around the implant. On the control side the perichondrium was shaped into a tube without an implant. Samples were taken 4, 12, and 20 weeks after operation. Pronounced neocartilage formation was seen on both sides, and had grown to form a tube around the implant. Also new bone formation was seen in 12 and 20 weeks. Foreign body reaction was seen inside the implants in every animal.
authors.affiliation: Department of Surgery, Oulu University Central Hospital, Finland.
authors.forename: M M
authors.initials: MM
authors.lastname: Ruuskanen
authors.forename: M J
authors.initials: MJ
authors.lastname: Kallioinen
authors.forename: O I
authors.initials: OI
authors.lastname: Kaarela
authors.forename: J A
authors.initials: JA
authors.lastname: Laiho
authors.forename: P O
authors.initials: PO
authors.lastname: Törmälä
authors.forename: T J
authors.initials: TJ
authors.lastname: Waris
mesh_terms: D000818:Animals; D001861:Bone Regeneration; D002356:Cartilage / Q000473:pathology / Q000502:physiology*; D005260:Female; D008297:Male; D011100:Polyglycolic Acid / Q000008:administration & dosage*; D019736:Prostheses and Implants; D011817:Rabbits; D012038:Regeneration; D012272:Ribs
chemical_list: D011100:Polyglycolic Acid