title: [Cytomegalic inclusion disease in a patient with systemic lupus].
abstract: Cytomegalovirus (CMV) infections acquire characteristics of special severity when they occur in patients suffering primary or secondary cellular immune depression. We present a case of pneumonia with fatal evolution caused by CMV, in a female patient suffering systemic lupus erythematosus. The underlying disease, of recent onset, presented multiorgan involvement (skin, joints, kidney, blood) which could be controlled with steroids and azathioprine. The patient presented a few days after she had overcome an acute outbreak of the disease, a febrile status with rapid evolution with a diffuse pulmonary interstitial infiltrate. Circulating anti CMV antibodies were detected, of IgM class, by a enzyme-immunoassay. The necropsy showed a multiorgan infiltrate (liver, lung, skin, kidney) with cells containing cytomegalic inclusion.
authors.affiliation: Departamento de Medicina Interna (Unidad de Colagenosis), Hospital Universitario Virgen del Rocío, Sevilla.
authors.forename: J
authors.initials: J
authors.lastname: Sánchez-Román
authors.forename: J M
authors.initials: JM
authors.lastname: Varela-Aguilar
authors.forename: I
authors.initials: I
authors.lastname: Fraile
authors.forename: J
authors.initials: J
authors.lastname: Andreu-Alvarez
authors.forename: J
authors.initials: J
authors.lastname: Fernández Alonso
mesh_terms: D000293:Adolescent; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D008099:Liver / Q000473:pathology; D008168:Lung / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D011658:Pulmonary Fibrosis / Q000175:diagnosis / Q000209:etiology / Q000473:pathology
vernacular_title: Enfermedad por inclusión citomegálica en paciente con lupus sistémico.