title: The human gene encoding phosphatidylinositol-3 kinase associated p85 alpha is at chromosome region 5q12-13.
abstract: The human chromosomal location of the gene encoding the phosphatidylinositol-3 kinase associated protein, p85 alpha, has been determined by analysis of its segregation in rodent-human hybrids and by chromosome in situ hybridization using a complementary DNA clone, GRB-1. The gene for p85 alpha is at chromosome region 5q13, perhaps near the gene encoding another receptor associated signal transducing protein, the GTPase activating protein.
authors.affiliation: Fels Institute for Cancer Research and Molecular Biology, Temple University School of Medicine, Philadelphia, Pennsylvania 19140.
authors.forename: L A
authors.initials: LA
authors.lastname: Cannizzaro
authors.forename: E Y
authors.initials: EY
authors.lastname: Skolnik
authors.forename: B
authors.initials: B
authors.lastname: Margolis
authors.forename: C M
authors.initials: CM
authors.lastname: Croce
authors.forename: J
authors.initials: J
authors.lastname: Schlesinger
authors.forename: K
authors.initials: K
authors.lastname: Huebner
mesh_terms: D019870:1-Phosphatidylinositol 4-Kinase; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D002895:Chromosomes, Human, Pair 5; D015894:Genome, Human; D006801:Humans; D010770:Phosphotransferases / Q000235:genetics*
chemical_list: D010770:Phosphotransferases; D019870:1-Phosphatidylinositol 4-Kinase