In vivo quantitation of water content in muscle tissues by NMR imaging.
The water contents of phantoms and muscle tissues were determined directly from NMR imaging experiments. The method involves the calculation of corrected proton densities using relaxation time determinations and suitable calibration phantoms. Comparison with the values obtained from the oven-dry method yields good agreement in normal rat skeletal tissue and in rats injected with red blood cells from sickle cell patients.
Rajanayagam
V
V
Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461.
Fabry
M E
ME
Gore
J C
JC
D000818:Animals; D001834:Body Water / Q000737:chemistry*; D002138:Calibration; D003903:Deuterium; D017666:Deuterium Oxide; D009682:Magnetic Resonance Spectroscopy; D008961:Models, Structural; D009132:Muscles / Q000737:chemistry*; D009532:Nickel; D011522:Protons; D051381:Rats; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013848:Thigh; D014867:Water
D011522:Protons; D014867:Water; C022838:nickel chloride; D009532:Nickel; D003903:Deuterium; D017666:Deuterium Oxide