[Formation of E-rosettes in homozygous nude mice (nu/nu) and heterozygotes (nu/+)].
Nude homozygote nu/nu mice show a deficiency in their cellular immune response, due to the fact that their thymic tissue is very scarce. The purpose of this paper has been to determine whether nu/nu mice, in the presence of T lymphocytes, have the capacity of forming E rosettes with sheep erythrocytes. These mice do present them, although in significantly lower quantities when compared to the nu/+ and normal ones of Balb/c strain. This result confirms previous information which point towards the existence of other types of markers on the surface of T lymphocytes in nu/nu mice.
Ramos-Zepeda
R
R
División de Patologia Experimental, Instituto Mexicano del Seguro Social, Guadalajara, Jalisco.
Ramos-Zepeda
Y
Y
González-Mendoza
A
A
Ramos-Zepeda
R
R
D000818:Animals; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis; D004912:Erythrocytes / Q000276:immunology / Q000378:metabolism; D006579:Heterozygote; D006720:Homozygote; D008297:Male; D008562:Membrane Glycoproteins; D051379:Mice; D008807:Mice, Inbred BALB C / Q000276:immunology; D008819:Mice, Nude / Q000235:genetics / Q000276:immunology*; D011971:Receptors, Immunologic / Q000378:metabolism; D012397:Rosette Formation; D012756:Sheep / Q000097:blood; D063267:Sialic Acid Binding Ig-like Lectin 1; D013601:T-Lymphocytes / Q000276:immunology* / Q000378:metabolism
D000945:Antigens, Differentiation, T-Lymphocyte; D008562:Membrane Glycoproteins; D011971:Receptors, Immunologic; D063267:Sialic Acid Binding Ig-like Lectin 1; C571167:Siglec1 protein, mouse
Formación de rosetas-E en ratones desnudos homocigotos (nu/nu) y heterocigotos (nu/+).