title: Changes in phosphatases and lipids following scrotal gamma irradiation in adult rat testis.
abstract: Effects of localized low (2.5 Gy) and high (10 Gy) levels of gamma irradiation on the testis of albino rats were studied. A marked increase in the testicular total lipid, phospholipid and cholesterol content was observed at all post-treatment intervals except at 16 weeks where the contents decreased. A significant decrease in the activity of acid phosphatase/g of testis was seen at both the doses, the minimum value being at 4 weeks. The decrease in acid phosphatase activity is correlated with the state of germ cell population in seminiferous tubule which is found to be depleted at 4 week interval. The alkaline phosphatase activity/g testis however, showed a significant increase, the maximum being at 4 weeks post-treatment. Thereafter, the values of the enzyme activity showed a slight recovery at 16 weeks post-irradiation. ATPase activity increased initially followed by a significant decrease at all post-treatment intervals.
authors.affiliation: Department of Biophysics, Panjab University, Chandigarh, India.
authors.forename: B
authors.initials: B
authors.lastname: Nehru
authors.forename: M
authors.initials: M
authors.lastname: Tiwari
authors.forename: A
authors.initials: A
authors.lastname: Kaul
authors.forename: M R
authors.initials: MR
authors.lastname: Bansal
mesh_terms: D000818:Animals; D005720:Gamma Rays; D050356:Lipid Metabolism; D008297:Male; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism*; D051381:Rats; D013737:Testis / Q000378:metabolism / Q000528:radiation effects*
chemical_list: D010744:Phosphoric Monoester Hydrolases