Disseminated histoplasmosis in an AIDS patient treated with itraconazole.
A patient with AIDS presented with a fever, shortness of breath and a productive cough. A provisional diagnosis of Pneumocystis carinii pneumonia was made; however, blood cultures and bone marrow examination revealed disseminated infection with Histoplasmosis capsulatum. This was treated by itraconazole with initial success, but the patient relapsed while on maintenance therapy.
Kell
P D
PD
Department of Genitourinary Medicine, St. Stephen's Clinic & Westminster Hospital.
Smith
D E
DE
Barton
S E
SE
Midgley
J
J
Samarasinghe
P L
PL
Gazzard
B G
BG
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D001769:Blood / Q000382:microbiology; D006658:Histoplasma / Q000302:isolation & purification; D006660:Histoplasmosis / Q000150:complications*; D006801:Humans; D017964:Itraconazole; D007654:Ketoconazole / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008264:Macrophages / Q000382:microbiology; D008297:Male; D009894:Opportunistic Infections / Q000150:complications* / Q000382:microbiology
D000935:Antifungal Agents; D017964:Itraconazole; D007654:Ketoconazole