title: ViraPap: can it help to reduce the need for colposcopy?
abstract: Two new tests recently became available for identifying cervical human papillomavirus (HPV). This study investigated the usefulness of the ViraPap and ViraType in the clinical setting. Thirty-six subjects considered to be at risk for HPV infection were examined; had specimens obtained for Papanicolaou smear (Pap smear), ViraPap, and ViraType; and were then referred for colposcopy. Results of these examinations were then compared to the findings of colposcopy and/or colposcopic biopsy. The sensitivity and specificity of the ViraPap in predicting an abnormality being found on colposcopic examination were 61.5% and 70%, respectively. Identifying the specific viral type by use of the ViraType did not prove to be clinically helpful in this population.
authors.affiliation: University of South Dakota Health Clinic, Vermillion.
authors.forename: D G
authors.initials: DG
authors.lastname: Mareck
authors.forename: D G
authors.initials: DG
authors.lastname: Woolard
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy / Q000592:standards; D003127:Colposcopy / Q000592:standards; D015342:DNA Probes / Q000592:standards; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000379:methods* / Q000592:standards; D065006:Papanicolaou Test; D027383:Papillomaviridae; D011933:Reagent Kits, Diagnostic / Q000592:standards*; D012680:Sensitivity and Specificity; D012703:Serotyping; D014412:Tumor Virus Infections / Q000175:diagnosis* / Q000453:epidemiology / Q000517:prevention & control; D002577:Uterine Cervical Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000517:prevention & control; D014626:Vaginal Smears / Q000592:standards
chemical_list: D015342:DNA Probes; D011933:Reagent Kits, Diagnostic