Nuclear ultrastructure of human parotid gland tumors with special focus on nuclear bodies.
The purpose of our study was to determine the morphology and the proportion of NB in 20 human parotid gland tumors. Types I and III NB were observed in benign as well as malignant tumors. Some atypical forms ("onion-like" NB and NB with lipidic inclusions) were found in benign tumors. The proportion of nuclear profiles containing one and more NB varied from 0 to 60% in the benign tumors, and from 4 to 50% in the malignant tumors. Nuclei containing 3 and more NB were observed as well in the benign as in the malignant tumors. The NB ratio cannot be taken for a malignancy criteria.
Dourov
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Department of Pathology and Electron Microscopy, School of Medicine, Université Libre de Bruxelles, Belgium.
Duquene
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D000230:Adenocarcinoma / Q000648:ultrastructure; D000235:Adenolymphoma / Q000648:ultrastructure; D008949:Adenoma, Pleomorphic / Q000648:ultrastructure; D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000648:ultrastructure; D003528:Carcinoma, Adenoid Cystic / Q000648:ultrastructure; D002467:Cell Nucleus / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D008297:Male; D008875:Middle Aged; D009208:Myoepithelioma / Q000648:ultrastructure; D010307:Parotid Neoplasms / Q000648:ultrastructure*