[Synthesis and testing of anticonvulsant properties of 5-benzylidene derivatives of 3-o-, 3-m- I 3-p-chlorophenyl-2-thiohydantoin].
Ten new 3-(o-, 3-(m- and 3-(p-chlorophenyl)-5-benzylidene derivatives of 2-thiohydantoin were obtained. Their IR spectra were recorded. The obtained compounds were tested for anticonvulsant activity using the test of minimal and maximal pentetrazol shock in mice, and the MES test in rats.
Rydzik
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Samodzielny Zakład Chemii Wyzszej Szkoły Pedagogicznej, Krakowie.
Szadowska
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A
Kiełek
M B
MB
D000818:Animals; D000927:Anticonvulsants; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D051381:Rats; D017208:Rats, Wistar; D013867:Thiohydantoins / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*
D000927:Anticonvulsants; D013867:Thiohydantoins
Synteza i badanie właściwości przeciwdrgawkowych 5-benzylidenowych pochodnych 3-o-, 3-m- I 3-p-chlorofenylo-2-tiohydantoiny.