Clinical comparison of the anticalculus efficacy of three commercially available dentifrices.
A three-month, double-blind, parallel and unsupervised clinical study was conducted to compare the effects on supragingival calculus formation of the following four dentifrices: 1) A placebo dentifrice containing 0.243% sodium fluoride in a silica base. 2) A commercially available anticalculus dentifrice containing 5.0% soluble pyrophosphate in a 0.243% sodium fluoride silica base. 3) A commercially available anticalculus dentifrice containing 1.3% soluble pyrophosphate and 1.5% of a Gantrez copolymer in a 0.243% sodium fluoride silica base. 4) A commercially available anticalculus dentifrice containing 3.3% soluble pyrophosphate and 1.0% of a Gantrez copolymer in a 0.243% sodium fluoride silica base. The three-month results indicated that the three commercially available anticalculus dentifrices provided statistically significant reductions (at the 99% level of confidence) in supragingival calculus formation of 43.87%, 46.60%, and 51.32% respectively, as compared to the placebo dentifrice. There was no statistically significant difference among the three commercially available anticalculus dentifrices.
Petrone
M
M
Lobene
R R
RR
Harrison
L B
LB
Volpe
A
A
Petrone
D M
DM
D000328:Adult; D003728:Dental Calculus / Q000517:prevention & control*; D003802:Dentifrices / Q000627:therapeutic use*; D011756:Diphosphates / Q000627:therapeutic use; D004311:Double-Blind Method; D005260:Female; D005459:Fluorides / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008298:Maleates / Q000627:therapeutic use*; D011145:Polyvinyls / Q000627:therapeutic use*
D003802:Dentifrices; D011756:Diphosphates; D008298:Maleates; D011145:Polyvinyls; C058026:polyvinylmethoxyethylene-maleic anhydride copolymer; D005459:Fluorides