(+)-CC-1065 produces bending of DNA that appears to resemble adenine/thymine tracts.
Lin
C H
CH
Drug Dynamics Institute, College of Pharmacy, Austin, Texas.
Sun
D Y
DY
Hurley
L H
LH
D000225:Adenine / Q000378:metabolism; D000903:Antibiotics, Antineoplastic / Q000494:pharmacology*; D001483:Base Sequence; D004247:DNA / Q000187:drug effects* / Q000378:metabolism; D000080890:Duocarmycins; D006878:Hydroxides; D017665:Hydroxyl Radical; D007211:Indoles; D007933:Leucomycins / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D009711:Nucleotides / Q000378:metabolism; D013057:Spectrum Analysis / Q000379:methods; D013941:Thymine / Q000378:metabolism
D000903:Antibiotics, Antineoplastic; D000080890:Duocarmycins; D006878:Hydroxides; D007211:Indoles; D007933:Leucomycins; D009711:Nucleotides; D017665:Hydroxyl Radical; C018782:CC 1065; D004247:DNA; D000225:Adenine; D013941:Thymine