title: [The isomorphism of univalent thallium and potassium in membrane transport processes].
abstract: Thallium ions (T1+) are able to isomorphous replacement of K+ in various minerals. The similarity between. T1+ and K+ is based upon the closeness of their crystal radii, hydration energy and mobility in aqueous solutions. Under certain conditions, the behaviour of T1+ can be substantially different from that of K+. As distinguished from K+, thallium ions tend to associate with different anions forming ion pairs and complexes. As a rule, the stability of these compounds is rather low, but in many cases the T(1+)-anion interactions appear to play an important role in discriminating between T1+ and K+ involved in transport processes. T1+/K(+)-selectivity characterizes K(+)-transport mechanisms operating in different kinds of cells membranes. In excitable membranes (muscles, nerves) the rates of passive transport of T1+ and K+ are similar. In non-excitable membranes (epithelial cells, red blood cells, mitochondrial membranes, bacteria) the T1+ passive permeability is about one or two orders of magnitude higher than that of K+. A moderate T1+/K(+)-selectivity was reported for various types of K+ active transport mechanisms.
authors.forename: I A
authors.initials: IA
authors.lastname: Skul'skiĭ
mesh_terms: D000818:Animals; D001419:Bacteria / Q000378:metabolism; D001692:Biological Transport / Q000502:physiology; D001693:Biological Transport, Active / Q000502:physiology; D003461:Crystallography; D006801:Humans; D008564:Membrane Potentials / Q000502:physiology; D011188:Potassium / Q000378:metabolism*; D000254:Sodium-Potassium-Exchanging ATPase / Q000502:physiology; D013793:Thallium / Q000378:metabolism*
chemical_list: D013793:Thallium; D000254:Sodium-Potassium-Exchanging ATPase; D011188:Potassium
vernacular_title: Izomorfizm odnovalentnogo talliia i kaliia v protsessakh membrannogo transporta.