[The significance of intercellular interrelations in the diagnosis of immunopathological states in patients with chronic neurological infections with a course of allergic disorders].
As many as 120 patients with different nosological forms of neuroinfections (encephalitis, encephalomyelitis, chorioependymitis and cerebral arachnoiditis) associated with allergic disturbances were examined by clinical and immunological methods. In addition to the common measurements of the relative and absolute content of T, B and 0 cells, cerebral antibodies and circulating immune complexes, the degree of the T component deficiency was calculated as compared to that in healthy persons as were intercellular and populational relations, which characterized individual immune responsiveness. It has been discovered that the populational relations undergo changes in initial manifestations of immune deficiency, becoming more remarkable as the pathological process progresses. The authors point to the necessity of analyzing the immunogram in patients placed under observation with a purpose of early diagnosis of immune imbalance that arises, and of defining the leading immunopathological mechanism to carry out more adequate and goal-oriented correction of immune disorders.
Evtushenko
S K
SK
Efimenko
V N
VN
Dukhovnaia
M A
MA
Simonian
V A
VA
D000293:Adolescent; D000328:Adult; D002450:Cell Communication / Q000276:immunology*; D003131:Combined Modality Therapy; D003141:Communicable Diseases / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis* / Q000188:drug therapy; D007154:Immune System Diseases / Q000175:diagnosis* / Q000188:drug therapy; D007111:Immunity, Cellular / Q000276:immunology; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000175:diagnosis* / Q000188:drug therapy
Znachenie mezhkletochnykh vzaimootnosheniĭ v diagnostike immunopatologicheskikh sostoianiĭ bol'nykh khronicheskimi neĭroinfektsiiami, protekaiushchimi s allergicheskimi narusheniiami.