title: Dietary fiber and lipid peroxidation: effect of dietary fiber on levels of lipids and lipid peroxides in high fat diet.
abstract: Effect of feeding coconut and blackgram fiber isolated as neutral detergent fiber (NDF) on the levels of lipids and lipid peroxides was studied in rats given a high fat diet. Concentration of cholesterol, free falty acid and phospholipids showed significant decrease in the serum, liver aorta and intestine of coconut and blackgram fiber groups. Concentration of malondialdehyde (MDA) and conjugated dienes was significantly decreased in liver and intestine of both fiber groups, while hydroperoxides showed significant increase in liver and heart of both the fiber groups. SOD and catalase activity was found to be increased in liver, intestine, heart proximal colon and distal colon of both the fiber groups. Serum ceruloplasmin levels showed a slight increase in animals fed coconut and blackgram fiber groups. Glutathione levels in liver, intestine proximal colon, distal colon and heart also showed a significant decrease in the animals of both the fiber groups.
authors.affiliation: Department of Biochemistry, University of Kerala Trivandrum, India.
authors.forename: B S
authors.initials: BS
authors.lastname: Thampi
authors.forename: G
authors.initials: G
authors.lastname: Manoj
authors.forename: S
authors.initials: S
authors.lastname: Leelamma
authors.forename: V P
authors.initials: VP
authors.lastname: Menon
mesh_terms: D000818:Animals; D004043:Dietary Fiber / Q000494:pharmacology*; D050356:Lipid Metabolism; D015227:Lipid Peroxidation; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains