[The effect of the small cardioactive peptide (b) on synaptic transmission efficiency and on the excitability of command neurons in the defensive behavior of the edible snail].
Small cardioactive peptide (b) (SCPb) application in concentration 5 X 10(-8) mol/l into the saline surrounding the snail CNS leads to an increase of amplitude of summate excitatory postsynaptic potential in the command neurones (CN) elicited by the intestinal nerve stimulation. Besides, SCPb causes an increase of excitability of the CN. Described effects can change the threshold of the neuronal net underlying avoidance behaviour. The possibility of integrative effects of peptides in low concentration on the behaviour is discussed.
Bravarenko
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D000818:Animals; D004305:Dose-Response Relationship, Drug; D004924:Escape Reaction / Q000187:drug effects* / Q000502:physiology; D006372:Helix, Snails / Q000187:drug effects* / Q000502:physiology; D066298:In Vitro Techniques; D007447:Invertebrate Hormones / Q000494:pharmacology*; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D009479:Neuropeptides / Q000494:pharmacology*; D013268:Stimulation, Chemical; D013569:Synapses / Q000187:drug effects* / Q000502:physiology; D009435:Synaptic Transmission / Q000187:drug effects* / Q000502:physiology
D007447:Invertebrate Hormones; D009479:Neuropeptides; C041307:small cardioactive peptide B
Vliianie malogo kardioaktivnogo peptida (b) na éffektivnost' sinapticheskoĭ peredachi i vozbudimost' komandnykh neĭronov oboronitel'nogo povedeniia vinogradnoĭ ulitki.