Development of the neural crest.
Mutations that affect the morphogenetic behaviour and differentiation of neural crest-derived cells in mouse embryos have been shown to alter genes that code for growth factors or growth factor receptors. Identification of these and other gene products provide opportunities to understand when and how developmentally distinct embryonic cell populations arise, and how interactions between localized developmental cues and responsive cell subpopulations can be modulated during development.
Marusich
M F
MF
Institute of Neuroscience, University of Oregon.
Weston
J A
JA
D000818:Animals; D002454:Cell Differentiation; D002642:Chick Embryo; D004627:Embryonic Induction; D005314:Embryonic and Fetal Development / Q000235:genetics; D005109:Extracellular Matrix / Q000502:physiology; D015870:Gene Expression; D006133:Growth Substances / Q000502:physiology; D008544:Melanocytes / Q000166:cytology; D051379:Mice / Q000196:embryology; D009024:Morphogenesis / Q000235:genetics; D009420:Nervous System / Q000196:embryology; D009432:Neural Crest / Q000254:growth & development*; D011956:Receptors, Cell Surface / Q000502:physiology; D013234:Stem Cells / Q000166:cytology; D014714:Vertebrates / Q000196:embryology
D006133:Growth Substances; D011956:Receptors, Cell Surface