title: [Acute pancreatitis and valproic acid].
abstract: An 11 year-old epileptic boy, treated with valproic acid developed after 11 months on therapy a severe acute pancreatitis. Pancreatitis recurred 18 months after re-exposure to the same drug. Twenty-four cases of valproic-acid induced acute pancreatitis have been reported in the literature. However, it remains a major anticonvulsant drug whose tolerance is usually excellent. This complication, although exceptional needs to be known so that the treatment can be stopped in due-time if not tolerated or to avoid eventual recurrence.
authors.affiliation: Département de pédiatrie, centre hospitalier général, Chambéry, France.
authors.forename: S
authors.initials: S
authors.lastname: Kayemba Kay's Kabangu
authors.forename: M
authors.initials: M
authors.lastname: Bovier Lapierre
authors.forename: E
authors.initials: E
authors.lastname: Jalaguier
mesh_terms: D000208:Acute Disease; D002648:Child; D004827:Epilepsy / Q000188:drug therapy; D006801:Humans; D008297:Male; D010195:Pancreatitis / Q000139:chemically induced*; D014635:Valproic Acid / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D014635:Valproic Acid
vernacular_title: Pancréatite aiguë et acide valproïque.