Genetic instability occurs sooner than expected: promotion, progression and clonality during hepatocarcinogenesis in the rat.
Sudilovsky
O
O
Institute of Pathology, Case Western Reserve University, Cleveland, OH 44106.
Hinrichsen
L I
LI
Hei
T K
TK
Whitacre
C M
CM
Wang
J H
JH
Kasturi
S
S
Jiang
S H
SH
Cechner
R
R
Miron
S
S
Abdul-Karim
F
F
D000782:Aneuploidy; D000818:Animals; D014408:Biomarkers, Tumor; D002273:Carcinogens; D006528:Carcinoma, Hepatocellular / Q000235:genetics / Q000473:pathology; D002454:Cell Differentiation; D002796:Choline Deficiency / Q000150:complications; D002869:Chromosome Aberrations; D002999:Clone Cells / Q000201:enzymology / Q000473:pathology; D003043:Cocarcinogenesis; D004273:DNA, Neoplasm / Q000235:genetics; D005260:Female; D006498:Hepatectomy; D006801:Humans; D006965:Hyperplasia; D008099:Liver / Q000187:drug effects / Q000201:enzymology / Q000473:pathology; D008113:Liver Neoplasms / Q000235:genetics / Q000473:pathology; D008114:Liver Neoplasms, Experimental / Q000139:chemically induced / Q000235:genetics* / Q000473:pathology; D008297:Male; D051379:Mice; D009154:Mutation; D009363:Neoplasm Proteins / Q000032:analysis; D011230:Precancerous Conditions / Q000235:genetics / Q000473:pathology; D051381:Rats; D011916:Rats, Inbred F344; D011919:Rats, Inbred Strains
D014408:Biomarkers, Tumor; D002273:Carcinogens; D004273:DNA, Neoplasm; D009363:Neoplasm Proteins