Experimental reduction of portal hypertension by mechanical increase of liver portal flow.
Studies on the isolated perfused rat liver demonstrated that an increase in portal pressure is associated with an increase in the portal blood flow in normal and in cirrhotic livers. In two pigs with portal hypertension mesenteric portal pressure was lowered by mechanically increasing the liver portal blood flow by means of a balloon pump around the portal vein.
Habib
N
N
Hepatobiliary and Liver Transplantation Unit, Royal Free Hospital, London, UK.
Houssin
D
D
Carol
C
C
Cardoso
J
J
Boisseau
C
C
Calmus
Y
Y
Ozier
Y
Y
Quere
J
J
Wood
C
C
McIntyre
N
N
D000818:Animals; D001783:Blood Flow Velocity; D006975:Hypertension, Portal / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D008102:Liver Circulation; D008106:Liver Cirrhosis, Experimental / Q000150:complications; D011169:Portal Vein / Q000503:physiopathology*; D051381:Rats; D011919:Rats, Inbred Strains; D013552:Swine