Post radiation sarcoma (malignant fibrous histiocytoma) of the cervical spine following ependymoma (a case report).
A case is reported of a 36 y/o man treated with radiation therapy for cervical cord ependymoma who developed malignant fibrous histiocytoma of the cervical spine 15 years later. Pathology revealed the sarcoma adjacent to the recurrent ependymoma. Post-radiation sarcomas following treatment of central nervous system malignancies is discussed.
Nadeem
S Q
SQ
Department of Oncology, Silvester Comprehensive Cancer Center, University of Miami.
Feun
L G
LG
Bruce-Gregorios
J H
JH
Green
B
B
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001254:Astrocytoma / Q000175:diagnosis; D002574:Cervical Vertebrae; D003131:Combined Modality Therapy; D003606:Dacarbazine / Q000008:administration & dosage; D003907:Dexamethasone / Q000008:administration & dosage; D003951:Diagnostic Errors; D004317:Doxorubicin / Q000008:administration & dosage; D004806:Ependymoma / Q000175:diagnosis / Q000532:radiotherapy* / Q000601:surgery; D018219:Histiocytoma, Benign Fibrous / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007796:Laminectomy; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D016609:Neoplasms, Second Primary / Q000209:etiology*; D011882:Radiotherapy, High-Energy / Q000009:adverse effects*; D013120:Spinal Cord Neoplasms / Q000175:diagnosis / Q000532:radiotherapy* / Q000601:surgery; D013125:Spinal Neoplasms / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology / Q000601:surgery
D003606:Dacarbazine; D003907:Dexamethasone; D004317:Doxorubicin