title: [Possibilities of the cytological method in the determination of therapeutic pathomorphosis of breast cancer].
abstract: Combined treatment was used in 380 patients with breast cancer stage IIB, IIIA and IIIB. Preoperative therapy included large-fraction radiation (213 patients) or CMP chemotherapy course (176 patients). It was followed by radical mastectomy and postoperative chemotherapy, radiation. Cytograms of the specimens from the removed tumors were compared to pretreatment findings. This served the basis for recognition of 4 degrees of breast cancer pathomorphosis. The scheme can be used as additional morphological information on the degree of the breast cancer destruction and should be taken into consideration together with other data.
authors.forename: N A
authors.initials: NA
authors.lastname: Sidorova
authors.forename: N N
authors.initials: NN
authors.lastname: Volchenko
authors.forename: E K
authors.initials: EK
authors.lastname: Saribekian
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D002277:Carcinoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D003581:Cytodiagnosis; D005069:Evaluation Studies as Topic; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D015409:Mastectomy, Radical; D008727:Methotrexate / Q000627:therapeutic use; D011879:Radiotherapy Dosage
chemical_list: D003520:Cyclophosphamide; D005472:Fluorouracil; D008727:Methotrexate
vernacular_title: Vozmozhnosti tsitologicheskogo metoda v ustanovlenii lechebnogo patomorfoza raka molochnoĭ zhelezy.