Extramammary Paget's disease and prostatic carcinoma.
A patient with perianal extramammary Paget's disease (EMPD) occurring simultaneously with prostatic adenocarcinoma is presented. Four previously reported cases of genital EMPD associated with prostatic carcinoma are reviewed. The use of immunohistologic techniques to help establish the diagnosis in some cases, and the relationship of EMPD to underlying adenocarcinoma of sweat glands and of the lower urinary and gastrointestinal tracts is discussed. The importance of a directed search for internal malignancy in the individual patient with EMPD is emphasised.
Gudmundsen
K J
KJ
Department of Dermatology, Mater Misericordiae Hospital, Dublin, Ireland.
Smith
J M
JM
Dervan
P A
PA
Powell
F C
FC
D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010145:Paget Disease, Extramammary / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*