title: Lymphoedema/hypercalcaemia syndrome mediated by parathyroid-hormone-related protein.
abstract: A 24-year-old woman presented with a cryptogenic, hypercalcaemic syndrome with metastatic pulmonary calcification and leg and massive breast enlargement and bilateral chylous pleural effusions compatible with a generalised lymphatic abnormality. The patient's serum parathyroid hormone-related protein concentration was very high at a time when she was significantly hypercalcaemic, implying that the hypercalcaemia was mediated by this protein.
authors.affiliation: Royal Brompton, National Heart Hospital, London, UK.
authors.forename: S
authors.initials: S
authors.lastname: Braude
authors.forename: A
authors.initials: A
authors.lastname: Graham
authors.forename: D
authors.initials: D
authors.lastname: Mitchell
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000097:blood* / Q000150:complications; D006961:Hyperparathyroidism / Q000175:diagnosis; D008209:Lymphedema / Q000097:blood* / Q000150:complications; D010281:Parathyroid Hormone / Q000097:blood*; D044162:Parathyroid Hormone-Related Protein; D011506:Proteins / Q000378:metabolism*; D013577:Syndrome
chemical_list: C470121:PTHLH protein, human; D010281:Parathyroid Hormone; D044162:Parathyroid Hormone-Related Protein; D011506:Proteins