title: Mammogram-directed fine-needle aspiration of nonpalpable breast lesions.
abstract: A prospective study was undertaken to evaluate the effectiveness of mammogram directed fine-needle aspiration cytology in women with nonpalpable abnormalities detected on mammogram. Seventy patients were entered into the research protocol, with 61 patients undergoing mammogram directed fine-needle aspiration. Forty-three of the aspirates were adequate for diagnosis. Fine-needle aspiration yielded an accurate diagnosis in 12 of the 14 carcinomas in which the sample was considered adequate, for a sensitivity of 87%. No patients were falsely diagnosed with malignant disease, a specificity of 100%. The predictive value of a positive test was 100%, and that of a negative test was 93%. We conclude that fine-needle aspiration cytology can aid in making a diagnosis when nonpalpable breast abnormalities are detected on mammogram.
authors.affiliation: Department of Surgery, David Grant USAF Medical Center, Travis Air Force Base, California 94535-5300.
authors.forename: G I
authors.initials: GI
authors.lastname: Arishita
authors.forename: B K
authors.initials: BK
authors.lastname: Cruz
authors.forename: C T
authors.initials: CT
authors.lastname: Harding
authors.forename: D R
authors.initials: DR
authors.lastname: Arbutina
mesh_terms: D001707:Biopsy, Needle / Q000379:methods*; D001943:Breast Neoplasms / Q000175:diagnosis*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000175:diagnosis*; D005260:Female; D005348:Fibrocystic Breast Disease / Q000175:diagnosis*; D006801:Humans; D008327:Mammography; D011237:Predictive Value of Tests; D011446:Prospective Studies