title: Radiotherapy for chemodectoma of the carotid body and ganglion nodosum.
abstract: Chemodectomas of the carotid body and of the glomus vagale are uncommon tumors of the head and neck. Between 1981 and 1986, 6 patients with advanced chemodectomas of either the carotid body (5 patients) or the glomus vagale (1 patient) were treated with radiotherapy at the University of Florida. Tumors were bilateral in 2 patients. Five patients have had no evidence of disease progression for 5, 5.5, 7, 7, and 8.5 years following irradiation. One of the 5 patients experienced complete regression, 2 noted partial regression, and 2 remained stable (without progression). One patient, who had received 2 prior operations and a course of irradiation at another institution, died of locally recurrent disease 5 years after re-irradiation at the University of Florida. No patient experienced a significant complication secondary to irradiation.
authors.affiliation: Department of Radiation Oncology, University of Florida College of Medicine, Gainesville.
authors.forename: F
authors.initials: F
authors.lastname: Guedea
authors.forename: W M
authors.initials: WM
authors.lastname: Mendenhall
authors.forename: J T
authors.initials: JT
authors.lastname: Parsons
authors.forename: R R
authors.initials: RR
authors.lastname: Million
mesh_terms: D000328:Adult; D002345:Carotid Body Tumor / Q000532:radiotherapy*; D003390:Cranial Nerve Neoplasms / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000532:radiotherapy; D009620:Nodose Ganglion; D010236:Paraganglioma, Extra-Adrenal / Q000532:radiotherapy*; D016896:Treatment Outcome