title: Somatostatin prevents acute pancreatitis after pancreatic duct sphincter hydrostatic balloon dilation in patients with idiopathic recurrent pancreatitis.
abstract: The purpose of this study was to determine whether prophylactic somatostatin infusion can prevent pancreatitis after hydrostatic balloon dilation of the pancreatic duct sphincter segment in 16 patients with idiopathic recurrent pancreatitis. This study demonstrated that prophylactic administration of somatostatin before, during, and after the procedure diminished the incidence and severity of acute pancreatitis. We recommend consideration of such prophylaxis in patients undergoing this procedure.
authors.affiliation: Gastroenterology Department, Hospital General del Oeste, M.S.A.S. Los Magallanes, Catia, Caracas, Venezuela.
authors.forename: M
authors.initials: M
authors.lastname: Guelrud
authors.forename: S
authors.initials: S
authors.lastname: Mendoza
authors.forename: L
authors.initials: L
authors.lastname: Viera
authors.forename: D
authors.initials: D
authors.lastname: Gelrud
mesh_terms: D000208:Acute Disease; D000328:Adult; D002404:Catheterization / Q000009:adverse effects*; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000009:adverse effects; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010183:Pancreatic Ducts; D010195:Pancreatitis / Q000517:prevention & control* / Q000628:therapy; D012008:Recurrence; D013004:Somatostatin / Q000627:therapeutic use*; D013105:Sphincterotomy, Transduodenal / Q000009:adverse effects
chemical_list: D013004:Somatostatin