title: Cerebral blood flow after ventriculoperitoneal shunt in children with hydrocephalus.
abstract: Fourteen hydrocephalic children were studied who were between the ages of 6 months and 14 years. Regional cerebral blood flow (rCBF) was measured by the 133Xe intravenous injection method after ventriculoperitoneal shunting. There was a negative correlation between slow flow and preoperative ventricular size (r = -0.718, P < 0.02), but there was no correlation between fast flow and preoperative ventricular size. There was also no correlation between rCBF and postoperative ventricular size. Postoperative IQ or development quotient showed a positive correlation with slow flow (r = 0.813, P < 0.01), but not with fast flow. It is suggested that in hydrocephalic children there is impairment of white-matter communicating fibres and secondary reduction in higher intellectual activity.
authors.affiliation: Department of Neurosurgery, Nagoya City University Medical School, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Mabe
authors.forename: K
authors.initials: K
authors.lastname: Suzuki
authors.forename: H
authors.initials: H
authors.lastname: Nagai
mesh_terms: D000293:Adolescent; D001783:Blood Flow Velocity / Q000502:physiology; D001921:Brain / Q000098:blood supply*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000000981:diagnostic imaging / Q000601:surgery*; D007223:Infant; D008297:Male; D011183:Postoperative Complications / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D012039:Regional Blood Flow / Q000502:physiology; D017287:Ventriculoperitoneal Shunt; D014980:Xenon Radioisotopes
chemical_list: D014980:Xenon Radioisotopes