Glomus tumour of the trachea: report of a case with microscopic, ultrastructural and immunohistochemical examination and review of the literature.
A case of glomus tumour of the trachea is reported. The patient, a 58-year-old man, complained of dyspnoea, cough and occasional haemoptysis for many years and had been misdiagnosed as having chronic bronchitis. The diagnosis of glomus tumour in a tissue sample taken by bronchoscopy was useful in planning adequate surgery. Light and electromicroscopy of the excised tumour confirmed the preoperative diagnosis. Immunohistochemical examination showed vimentin and actin in the tumour cells, and negativity for high and low molecular weight keratins, desmin, neurofilaments, and factor VIII-related antigen, findings similar to glomus tumours of other sites.
García-Prats
M D
MD
Department of Pathology, Hospital 12 de Octubre, Madrid, Spain.
Sotelo-Rodríguez
M T
MT
Ballestín
C
C
Martínez-González
M A
MA
Roca
R
R
Alfaro
J
J
De Miguel
E
E
D000199:Actins / Q000032:analysis; D001999:Bronchoscopy; D005918:Glomus Tumor / Q000737:chemistry / Q000648:ultrastructure*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D014134:Tracheal Neoplasms / Q000737:chemistry / Q000648:ultrastructure*; D014746:Vimentin / Q000032:analysis
D000199:Actins; D014746:Vimentin