title: Human serum non-antibody inhibitors towards SA-11 rotavirus hemagglutination.
abstract: In the present work the non-antibody inhibitory activity of human serum towards SA-11 rotavirus hemagglutination (HA) has been studied. Among human serum protein components, inhibitory activity was recovered in fractions III (beta-globulin), IV (alpha-globulin) and IV (glycoprotein). Additional experiments performed with purified lipoprotein sub-classes and their lipid and apolipoprotein moieties demonstrated the ability of HDL and, HDL1 to prevent SA-11 HA.
authors.affiliation: Laboratorio di Ultrastrutture, Istituto Superiore di Sanità, Roma.
authors.forename: F
authors.initials: F
authors.lastname: Superti
authors.forename: M
authors.initials: M
authors.lastname: Marchetti
authors.forename: L
authors.initials: L
authors.lastname: Seganti
authors.forename: M P
authors.initials: MP
authors.lastname: Conte
authors.forename: N
authors.initials: N
authors.lastname: Orsi
mesh_terms: D000818:Animals; D001798:Blood Proteins / Q000378:metabolism*; D002460:Cell Line; D005260:Female; D006023:Glycoproteins / Q000097:blood; D006385:Hemagglutination Inhibition Tests; D006386:Hemagglutination Tests; D006387:Hemagglutination, Viral; D006801:Humans; D008075:Lipoproteins, HDL / Q000097:blood; D008297:Male; D012401:Rotavirus / Q000378:metabolism*; D012712:Serum Globulins / Q000378:metabolism*
chemical_list: D001798:Blood Proteins; D006023:Glycoproteins; D008075:Lipoproteins, HDL; D012712:Serum Globulins