title: Adenocarcinoma of the retinal pigment epithelium in the guppy Poecilia reticulata Peters.
abstract: A single case of adenocarcinoma of the retinal pigment epithelium occurred in a guppy, Poecilia reticulata, Peters. This is the first such tumour reported from fishes. The left eye of the affected fish was severely exophthalmic because of a large intraocular tumour mass. The tumour, which displaced normal retina anteriorly, consisted mainly of melanin-containing epithelial cells. Neoplastic cells were bilayered and arranged in a tubular pattern. The tumour was confined to the orbit. Although the specimen was from a group exposed to a mixture of halogenated organic compounds, the lesion was not considered to have been chemically induced because of its rare occurrence within the group as a whole.
authors.affiliation: U.S. Environmental Protection Agency, Center for Marine and Estuarine Disease Research, Gulf Breeze, Florida 32561.
authors.forename: J W
authors.initials: JW
authors.lastname: Fournie
authors.forename: W E
authors.initials: WE
authors.lastname: Hawkins
authors.forename: W W
authors.initials: WW
authors.lastname: Walker
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D005393:Fish Diseases / Q000473:pathology*; D010857:Pigment Epithelium of Eye; D011036:Poecilia; D012164:Retinal Diseases / Q000473:pathology / Q000662:veterinary*