Evidence for the formation of superoxide ion from the reaction of Cu(II)-ethylenediamine complex with hydrogen peroxide.
Formation of superoxide ion (O2-) from the reaction of CuII(en)2 (en: ethylenediamine) with hydrogen peroxide (H2O2) was first determined spectrophotometrically by use of nitro blue tetrazolium (NBT) in aqueous solutions. From this result, it has been suggested that superoxide ion is generated as an intermediate at the first reaction step between CuII(en)2 and H2O2.
Ozawa
T
T
Division of Chemical Pharmacology, National Institute of Radiological Sciences, Chiba.
Hanaki
A
A
D003300:Copper; D004578:Electron Spin Resonance Spectroscopy; D005029:Ethylenediamines; D006861:Hydrogen Peroxide; D009580:Nitroblue Tetrazolium; D013481:Superoxides
D005029:Ethylenediamines; D013481:Superoxides; D009580:Nitroblue Tetrazolium; D003300:Copper; D006861:Hydrogen Peroxide