An epizootic of histoplasmosis duboisii (African histoplasmosis) in an American baboon colony.
Histoplasmosis duboisii, a chronic granulomatous disease caused by Histoplasma capsulatum var. duboisii, was diagnosed in 21 baboons at a large primate colony in San Antonio, Texas. Diagnosis was based on finding 8 to 15 microns-diameter yeast cells in histologic sections. Therapy with drugs was unsuccessful. Surgical removal of lesions was the primary treatment. Epidemiologic data suggest the incubation period to be at least 9 months. The most likely route of infection was oral and happened during grooming by the baboons.
Butler
T M
TM
Department of Laboratory Animal Medicine, Southwest Foundation for Biomedical Research, San Antonio, TX.
Hubbard
G B
GB
D000818:Animals; D004196:Disease Outbreaks / Q000662:veterinary*; D006660:Histoplasmosis / Q000453:epidemiology / Q000473:pathology / Q000662:veterinary*; D008992:Monkey Diseases / Q000453:epidemiology*; D010215:Papio; D013781:Texas / Q000453:epidemiology