title: Complete nucleotide sequence of segment 5 of epizootic haemorrhagic disease virus; the outer capsid protein VP5 is homologous to the VP5 protein of bluetongue virus.
abstract: The complete nucleotide sequence of a cDNA clone representing the segment 5 RNA of epizootic haemorrhagic disease virus (EHDV) United States serotype 1 was determined. The 5' and 3' termini of the RNA are complementary and are capable of forming secondary structures. The comparison of the predicted amino acid sequence of the encoded outer capsid protein (VP5) with the sequences of VP5 from four serotypes of bluetongue virus, the prototype orbivirus, revealed that the protein shares 59% to 62% homologies with various BTV serotypes, including a single conserved glycine residue at the amino terminus. The sequence has been submitted to the Genebank databox (X55782).
authors.affiliation: Department of Environmental Health, University of Alabama, Birmingham 35294.
authors.forename: H
authors.initials: H
authors.lastname: Iwata
authors.forename: T
authors.initials: T
authors.lastname: Hirasawa
authors.forename: P
authors.initials: P
authors.lastname: Roy
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D001820:Bluetongue virus / Q000235:genetics*; D002213:Capsid / Q000235:genetics*; D036022:Capsid Proteins; D015342:DNA Probes; D004279:DNA, Viral / Q000737:chemistry*; D006476:Orthohantavirus / Q000235:genetics*; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009693:Nucleic Acid Hybridization; D016366:Open Reading Frames / Q000235:genetics; D012689:Sequence Homology, Nucleic Acid
chemical_list: D036022:Capsid Proteins; D015342:DNA Probes; D004279:DNA, Viral