Proteolytic activity of vitreous-humour.
It has been found that the bovine vitreous--humour did not digest in vitro collagen at physiological and acidic pH. A proteolytic activity against haemoglobin in acid pH was found both in bovine and human vitreous-humours. The activity of human vitreous-humour increased significantly in endophtalmitis and glaucoma. In all pathological conditions studied the pH optima were at more acidic values than in control.
Wolańska
M
M
Department of Biochemistry, Medical Academy, Białystok, Poland.
Bakunowicz-Lazarczyk
A
A
Bańkowski
E
E
D000818:Animals; D002403:Cathepsins / Q000378:metabolism; D002417:Cattle; D003094:Collagen / Q000378:metabolism*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D003012:Microbial Collagenase / Q000378:metabolism*; D051381:Rats; D014822:Vitreous Body / Q000201:enzymology*
D003094:Collagen; D002403:Cathepsins; D003012:Microbial Collagenase