Role of the beta-adrenergic receptor kinase in desensitization of the alpha 2-adrenergic receptor.
Liggett
S B
SB
Department of Medicine (Pulmonary and Cardiology), Duke University Medical Center, Durham, NC 27710.
Ostrowski
J
J
Chesnut
L C
LC
Caron
M G
MG
Lefkowitz
R J
RJ
D000262:Adenylyl Cyclases / Q000378:metabolism; D000595:Amino Acid Sequence; D000818:Animals; D002460:Cell Line; D006224:Cricetinae; D017868:Cyclic AMP-Dependent Protein Kinases; D004837:Epinephrine / Q000494:pharmacology; D019204:GTP-Binding Proteins / Q000378:metabolism; D006801:Humans; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D011494:Protein Kinases / Q000378:metabolism*; D011942:Receptors, Adrenergic, alpha / Q000235:genetics / Q000378:metabolism*; D011943:Receptors, Adrenergic, beta / Q000235:genetics / Q000378:metabolism; D051552:beta-Adrenergic Receptor Kinases
D011942:Receptors, Adrenergic, alpha; D011943:Receptors, Adrenergic, beta; D011494:Protein Kinases; D017868:Cyclic AMP-Dependent Protein Kinases; D051552:beta-Adrenergic Receptor Kinases; D019204:GTP-Binding Proteins; D000262:Adenylyl Cyclases; D004837:Epinephrine