title: [Cavinton in the prevention of the convulsive syndrome in children after birth injury].
abstract: The authors studied the efficacy of cavinton as an agent helpful in preventing neurologic disorders in the newborn with hypoxic ischemic encephalopathy due to intracranial birth trauma. The short-term results of the treatment were elucidated in 61 children. In group I including 20 persons given conventional therapy, the disappearance of seizures was recorded in 6 patients; out of 41 children (group II) given additionally cavinton, in 27. Twenty-nine children were followed up for a year. In group I, convulsive paroxysms recurred in 4 patients, whereas in the group II children, no convulsive syndrome was recorded on the follow-up. The group II children also showed a decrease of the phenomena of intracranial hypertension and normalization of the psychomotor development. The preventive effect of cavinton seen in children with a history of birth trauma may be accounted for by its capacity of normalizing cerebrovascular disorders and by its own anticonvulsive properties.
authors.forename: A A
authors.initials: AA
authors.lastname: Dutov
authors.forename: G A
authors.initials: GA
authors.lastname: Gal'tvanitsa
authors.forename: V A
authors.initials: VA
authors.lastname: Volkova
authors.forename: O N
authors.initials: ON
authors.lastname: Sukhanova
authors.forename: T G
authors.initials: TG
authors.lastname: Lavrishcheva
authors.forename: A P
authors.initials: AP
authors.lastname: Petrov
mesh_terms: D000927:Anticonvulsants / Q000008:administration & dosage*; D001720:Birth Injuries / Q000150:complications*; D001930:Brain Injuries / Q000150:complications*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D012640:Seizures / Q000209:etiology / Q000517:prevention & control*; D014748:Vinca Alkaloids / Q000008:administration & dosage*
chemical_list: D000927:Anticonvulsants; D014748:Vinca Alkaloids; C013983:vinpocetine
vernacular_title: Kavinton v profilaktike sudorozhnogo sindroma u deteĭ, perenesshikh rodovuiu travmu.