[The ratio of the cAMP content of the plasma and lymphocytes in bronchial asthma patients].
The author revealed a reduction of cAMP in the blood plasma and lymphocytes in patients with a severe course of infection-dependent bronchial asthma during exacerbation of the disease. Continuing use of glucocorticoid hormones (hormone-dependent asthma) is accompanied by normalization of cAMP values. It is suggested that glucocorticoids produce a stimulating effect on nucleotide synthesis. It is also not excluded that there is also another mechanism of cAMP increase, namely anti-phosphodiesterase effect of glucocorticoids.
Diban
G
G
D001249:Asthma / Q000097:blood* / Q000628:therapy; D000242:Cyclic AMP / Q000097:blood*; D006801:Humans; D008214:Lymphocytes / Q000737:chemistry*; D011863:Radioimmunoassay; D012074:Remission Induction
D000242:Cyclic AMP
Sootnoshenie soderzhaniia tsAMF v plazme i limfotsitakh u bol'nykh bronkhial'noĭ astmoĭ.