title: Ispaghula husk may relieve gastrointestinal symptoms in ulcerative colitis in remission.
abstract: The efficiency of ispaghula husk in relieving gastrointestinal symptoms in patients with ulcerative colitis in remission was studied in a placebo-controlled trial running for 4 months. Twenty-nine patients (81%) completed the trial; four withdrew after colitis relapse (three while receiving placebo). Grading of symptoms judged ispaghula to be consistently superior to placebo (p less than 0.001) and associated with a significantly higher rate of improvement (69%) than placebo (24%) (p less than 0.001). The results show that ispaghula can be helpful in the management of gastrointestinal symptoms in quiescent ulcerative colitis.
authors.affiliation: Dept. of Internal Medicine, Central Hospital, Norrköping, Sweden.
authors.forename: C
authors.initials: C
authors.lastname: Hallert
authors.forename: M
authors.initials: M
authors.lastname: Kaldma
authors.forename: B G
authors.initials: BG
authors.lastname: Petersson
mesh_terms: D000328:Adult; D000368:Aged; D003093:Colitis, Ulcerative / Q000178:diet therapy*; D004043:Dietary Fiber / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011620:Psyllium / Q000627:therapeutic use*; D011795:Surveys and Questionnaires
chemical_list: D004043:Dietary Fiber; D011620:Psyllium