title: [Sensitivity of Hemophilus strains to fluoroquinolones].
abstract: The sensitivity of haemophilus strains isolated from patients freshly were tested by newly produced fluorokinolones with broader antimicrobial activity and excellent pharmacokinetic features. We found a high sensitivity of all haemophilus strains tested by ofloxacin with Resistest method. The minimal inhibitory concentrations in Levinthal bouillon medium ranged between 0,015-0,03 micrograms/ml and the exerted a bactericidal effect. Since these concentrations are only a small portion of the blood and tissue levels of the ofloxacin, therefore the fluorokinolones proved to be effective antibacterial drugs in the therapy of the haemophilus infections.
authors.affiliation: Semmelweis Orvostudományi Egyetem, Budapest.
authors.forename: Z
authors.initials: Z
authors.lastname: Csukás
authors.forename: L
authors.initials: L
authors.lastname: Sztankov
authors.forename: I
authors.initials: I
authors.lastname: Cserba
mesh_terms: D004352:Drug Resistance, Microbial; D006190:Haemophilus / Q000187:drug effects*; D006801:Humans; D066298:In Vitro Techniques; D015242:Ofloxacin / Q000494:pharmacology*; D015366:Pefloxacin; D015363:Quinolones / Q000494:pharmacology*
chemical_list: D015363:Quinolones; D015366:Pefloxacin; D015242:Ofloxacin
vernacular_title: Haemophilus törzsek fluorokinolonok iránti érzékenysége.