Starch malabsorption and stool excretion are influenced by the menstrual cycle in women consuming low-fibre Western diets.
The objectives of the study were to determine whether the follicular (F; days 6-11) and luteal (L; days 16-21) phases of the menstrual cycle were associated with changes in starch malabsorption, stool bulking, stool mucinase, and beta-glucuronidase activities in 10 women (24.1 +/- 0.7 years old) eating a standardized low-fibre diet. Starch malabsorption, measured by breath hydrogen excretion after a breakfast of pureed chickpea (days 10 and 20) versus 10 g lactulose (days 11 and 21), decreased from 9.7 +/- 1.8 g/50 g starch ingested (F) to 6.6 +/- 1.8 g/50 g starch ingested (L) (P less than 0.05). Stool wet weight decreased from 84.5 +/- 10.1 g/day (F) to 52.2 +/- 5.8 g/day (L) (P less than 0.002). Stool dry weight decreased from 20.2 +/- 1.9 g/day (F) to 14.2 +/- 1.1 g/day (L) (P less than 0.006). Stool nitrogen excretion decreased from 1.81 +/- 0.19 g/day (F) to 0.82 +/- 0.06 g/day (L) (P less than 0.006). Stool mucinase and beta-glucuronidase activities were unaffected by the menstrual cycle. These results indicate that women eating low-fibre Western diets may be more prone to constipation during the luteal phase of the menstrual cycle.
McBurney
M I
MI
Dept. of Foods & Nutrition, University of Alberta, Edmonton, Canada.
D000328:Adult; D000416:Alberta; D004043:Dietary Fiber / Q000378:metabolism*; D005243:Feces / Q000201:enzymology*; D005260:Female; D005498:Follicular Phase / Q000502:physiology*; D005966:Glucuronidase / Q000378:metabolism; D006801:Humans; D008183:Luteal Phase / Q000502:physiology*; D008286:Malabsorption Syndromes / Q000378:metabolism*; D011133:Polysaccharide-Lyases / Q000378:metabolism; D013213:Starch / Q000378:metabolism*
D004043:Dietary Fiber; D013213:Starch; D005966:Glucuronidase; D011133:Polysaccharide-Lyases; C100002:hyaluronate lyase