title: Multisite and hierarchal protein phosphorylation.
abstract: Multisite phosphorylation is a prevalent form of protein modification whose full implications are just beginning to be understood. Multiple protein modifications expand the repertoire of structural changes that can be elicited in proteins and permit more intricate regulatory circuits to operate.
authors.affiliation: Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis 46202-5122.
authors.forename: P J
authors.initials: PJ
authors.lastname: Roach
mesh_terms: D000595:Amino Acid Sequence; D003599:Cytoskeleton / Q000378:metabolism; D004798:Enzymes / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D008969:Molecular Sequence Data; D009687:Nuclear Proteins / Q000378:metabolism; D010749:Phosphoprotein Phosphatases / Q000378:metabolism; D010766:Phosphorylation; D011494:Protein Kinases / Q000378:metabolism; D011506:Proteins / Q000378:metabolism*
chemical_list: D004798:Enzymes; D008565:Membrane Proteins; D009687:Nuclear Proteins; D011506:Proteins; D011494:Protein Kinases; D010749:Phosphoprotein Phosphatases