title: A gene in the archaebacterium Sulfolobus solfataricus that codes for a protein equivalent to the alpha subunits of the signal recognition particle receptor in eukaryotes.
abstract: We have sequenced a gene in the archaebacterium Sulfolobus solfataricus that codes for a protein that shows sequence similarity to the alpha subunit of the signal recognition particle receptor or docking protein in eukaryotes and the product of the ftsY gene in Escherichia coli. Comparison of the Sulfolobus 'docking protein' with its eukaryotic and eubacterial counterparts showed that the region of highest sequence similarity corresponds to a GTP-binding site. The presence of this gene in archaebacteria suggests that some of the components involved in protein transport have been conserved in the three kingdoms.
authors.affiliation: Department of Biochemistry and Microbiology, University of Victoria, British Columbia, Canada.
authors.forename: C
authors.initials: C
authors.lastname: Ramírez
authors.forename: A T
authors.initials: AT
authors.lastname: Matheson
mesh_terms: D000595:Amino Acid Sequence; D001105:Archaea / Q000235:genetics*; D001483:Base Sequence; D001665:Binding Sites; D001693:Biological Transport, Active; D004926:Escherichia coli / Q000235:genetics; D006801:Humans; D046911:Macromolecular Substances; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D011487:Protein Conformation; D011956:Receptors, Cell Surface / Q000235:genetics*; D018160:Receptors, Cytoplasmic and Nuclear; D018000:Receptors, Peptide; D016415:Sequence Alignment; D012689:Sequence Homology, Nucleic Acid
chemical_list: D046911:Macromolecular Substances; D011956:Receptors, Cell Surface; D018160:Receptors, Cytoplasmic and Nuclear; D018000:Receptors, Peptide; C036318:signal peptide receptor