Beta-receptor regulation: dynamics of density and function throughout the cardiac cycle.
Recent research shows beta-receptors in human myocardium can lose sensitivity to endogenous and exogenous stimulation. This decreased sensitivity known as down-regulation, explains several therapy. The clinical phenomena of concern to nursing and helps predict patient response to therapy. The concept of lusitropy (process of relaxation) and the use of pharmacologic beta-modulators are added to the traditional hemodynamic framework as integral parts of a new dynamic model.
Gibson
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RK
D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D008955:Models, Cardiovascular; D009200:Myocardial Contraction / Q000187:drug effects* / Q000502:physiology; D011943:Receptors, Adrenergic, beta / Q000187:drug effects* / Q000502:physiology; D012106:Research
D011943:Receptors, Adrenergic, beta