title: [Synthesis and testing of anticonvulsant properties of 5-benzylidene derivatives of 3-o-, 3-m- I 3-p-chlorophenyl-2-thiohydantoin].
abstract: Ten new 3-(o-, 3-(m- and 3-(p-chlorophenyl)-5-benzylidene derivatives of 2-thiohydantoin were obtained. Their IR spectra were recorded. The obtained compounds were tested for anticonvulsant activity using the test of minimal and maximal pentetrazol shock in mice, and the MES test in rats.
authors.affiliation: Samodzielny Zakład Chemii Wyzszej Szkoły Pedagogicznej, Krakowie.
authors.forename: E
authors.initials: E
authors.lastname: Rydzik
authors.forename: A
authors.initials: A
authors.lastname: Szadowska
authors.forename: M B
authors.initials: MB
authors.lastname: Kiełek
mesh_terms: D000818:Animals; D000927:Anticonvulsants; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D051381:Rats; D017208:Rats, Wistar; D013867:Thiohydantoins / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000927:Anticonvulsants; D013867:Thiohydantoins
vernacular_title: Synteza i badanie właściwości przeciwdrgawkowych 5-benzylidenowych pochodnych 3-o-, 3-m- I 3-p-chlorofenylo-2-tiohydantoiny.