title: Accumulation of leucocytes labelled with technetium-99m hexamethylpropylene amine oxime in malignant abdominal tumours.
abstract: A total of 343 leucocyte scans labelled with technetium-99m hexamethylpropylene amine oxime were reviewed that had been performed in 338 patients suspected of having abdominal infection or inflammation. There was uptake by malignant abdominal tumours in 10 cases (2.9%), which represents 62.5% of known malignancies at the time of the scintigram. Accumulation was seen in 8 patients with adenocarcinoma of the colon associated with a secondary infection in the tumour or pericolic inflammation. A large tumour that had spread beyond the bowel wall was related to a positive scintigram. Accumulation was also found twice in a malignant fibrous histiocytoma in which bleeding and an inflammatory reaction to necrosis were probably responsible for the uptake. The relevant treatment was delayed for 2 weeks-2 months in 4 patients with adenocarcinoma of the colon in whom the positive uptake was regarded as confirmation of the clinically suspected acute diverticulitis.
authors.affiliation: Department of Radiology, Päijät-Häme Central Hospital, Lahti, Finland.
authors.forename: E
authors.initials: E
authors.lastname: Lantto
authors.forename: K
authors.initials: K
authors.lastname: Järvi
authors.forename: T
authors.initials: T
authors.lastname: Lantto
authors.forename: S
authors.initials: S
authors.lastname: Ristkari
authors.forename: M
authors.initials: M
authors.lastname: Vorne
mesh_terms: D000008:Abdominal Neoplasms / Q000000981:diagnostic imaging* / Q000453:epidemiology; D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000453:epidemiology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001079:Apudoma / Q000000981:diagnostic imaging / Q000453:epidemiology; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000000981:diagnostic imaging / Q000453:epidemiology; D006801:Humans; D007962:Leukocytes; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D010091:Oximes; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D019690:Technetium Tc 99m Exametazime
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime