An unusual cutaneous lymphoma with B and T cell characteristics showing gallium-67 positive benign thymic hyperplasia following intensive chemotherapy.
This case illustrates two interesting features. Firstly it describes an unusual cutaneous lymphoma in an adolescent girl. This lymphoma showed features of B and T cell lineages with rearrangements of both immunoglobulin heavy chain and T cell beta chain genes. Secondly it describes the development of gallium-67 citrate (67Ga) scan positive benign thymic hyperplasia, 15 months after diagnosis and three months after cessation of intensive chemotherapy.
Young
G A
GA
Kanematsu Laboratories, Royal Prince Alfred Hospital, Sydney, NSW, Australia.
Grace
J
J
Williams
B G
BG
Trent
R J
RJ
McLaughlin
A F
AF
McCaughan
B
B
D000293:Adolescent; D000970:Antineoplastic Agents / Q000009:adverse effects; D005260:Female; D005710:Gallium Radioisotopes; D015321:Gene Rearrangement; D015333:Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; D006801:Humans; D007143:Immunoglobulin Heavy Chains / Q000235:genetics; D016393:Lymphoma, B-Cell / Q000188:drug therapy*; D016410:Lymphoma, T-Cell, Cutaneous / Q000188:drug therapy* / Q000235:genetics; D011877:Radionuclide Imaging; D012878:Skin Neoplasms / Q000188:drug therapy* / Q000235:genetics; D013952:Thymus Hyperplasia / Q000139:chemically induced / Q000000981:diagnostic imaging*
D000970:Antineoplastic Agents; D005710:Gallium Radioisotopes; D007143:Immunoglobulin Heavy Chains