Pheromone signaling pathways in yeast.
The discovery that the transducing G protein of the Saccharomyces cerevisiae mating pheromone response figures centrally in signal adaptation was the focus of considerable excitement in the past year. Not only does activated G alpha in this system stimulate an adaptive signal but G beta undergoes a desensitizing phosphorylation in response to pheromone signaling.
Reed
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Department of Molecular Biology, Scripps Research Institute, La Jolla, CA 92037.
D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism*; D019204:GTP-Binding Proteins / Q000235:genetics / Q000502:physiology*; D015966:Gene Expression Regulation, Fungal; D005800:Genes, Fungal; D006160:Guanosine Triphosphate / Q000378:metabolism; D000072235:Mating Factor; D008954:Models, Biological; D010455:Peptides / Q000235:genetics / Q000502:physiology*; D010766:Phosphorylation; D011494:Protein Kinases / Q000235:genetics / Q000378:metabolism; D011499:Protein Processing, Post-Translational; D011956:Receptors, Cell Surface / Q000235:genetics / Q000378:metabolism; D051964:Receptors, Mating Factor; D018000:Receptors, Peptide; D012098:Reproduction; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000502:physiology*; D015398:Signal Transduction; D014157:Transcription Factors
D005656:Fungal Proteins; D010455:Peptides; D011956:Receptors, Cell Surface; D051964:Receptors, Mating Factor; D018000:Receptors, Peptide; D014157:Transcription Factors; D000072235:Mating Factor; D006160:Guanosine Triphosphate; D011494:Protein Kinases; D019204:GTP-Binding Proteins