title: [Inhibiting effect of a pyrophosphate-dentifrice on calculus formation].
abstract: Anticalculus dentifrices containing pyrophosphate salts have been shown to reduce calculus formation. The purpose of this double-blind, cross-over study was to compare the effects of a pyrophosphate dentifrice with a placebo on supragingival calculus formation in highly calculus-prone subjects. 60 volunteers completed a compliance period during which meticulous full-mouth scaling was performed. Subjects were randomly assigned either to placebo (F-Antibelag Gel) or to the test group (F-Antibelag Gel + K4P2O7/Na4P2O7). Participants were told to brush twice daily with their assigned dentifrice, use only the brushes provided and to abstain from any other oral hygiene procedures. After a three month period a second full-mouth scaling was performed, and according to the cross-over design of this study the participants used the alternative placebo or, respectively, dentifrice for another three months. Baseline scores and control scores after 1, 2 and 3 months were obtained using the Volpe-Manhold-Index and the Marginal-Line-Calculus-Index. A micromorphological SEM Calculus Index was introduced using replicas from interdental areas of mandibular incisors (score 0-3). Both test groups showed significantly less accumulation of supragingival calculus of 25.5% (VMI) and 19.5% (MLCI) and significantly less SEM detectable calculus (24%) with the pyrophosphate dentifrice than with the placebo. It is concluded that the test dentifrice inhibits the formation of calculus.
authors.affiliation: Sektion Stomatologie an der Medizinischen Akademie Erfurt.
authors.forename: A
authors.initials: A
authors.lastname: Kurbad
authors.forename: P
authors.initials: P
authors.lastname: Gängler
authors.forename: T
authors.initials: T
authors.lastname: Hoffmann
authors.forename: T
authors.initials: T
authors.lastname: Kirchner
authors.forename: W
authors.initials: W
authors.lastname: Weinert
mesh_terms: D000328:Adult; D003728:Dental Calculus / Q000517:prevention & control*; D003802:Dentifrices / Q000627:therapeutic use*; D011756:Diphosphates / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D005782:Gels; D006801:Humans; D008297:Male; D008875:Middle Aged; D009911:Oral Hygiene Index
chemical_list: D003802:Dentifrices; D011756:Diphosphates; D005782:Gels; C003319:sodium pyrophosphate
vernacular_title: Zahnsteinbildungshemmung durch ein pyrophosphathaltiges Zahnputzgel.