title: On the voltage dependence of inactivation in the sodium channel of the squid giant axon.
abstract: Measurements of the macroscopic sodium current in the squid giant axon show that the inactivation gate carries around 1.3 units of electronic charge. The contrary evidence from single-channel studies is considered, and a modified series-parallel model of the sodium channel is proposed that might help to resolve the disagreement.
authors.affiliation: Physiological Laboratory, University of Cambridge, U.K.
authors.forename: R D
authors.initials: RD
authors.lastname: Keynes
mesh_terms: D000818:Animals; D001369:Axons / Q000378:metabolism*; D049832:Decapodiformes; D007700:Kinetics; D008564:Membrane Potentials; D008959:Models, Neurological; D015222:Sodium Channels / Q000378:metabolism*
chemical_list: D015222:Sodium Channels