Detection of human papilloma virus (HPV) in laryngeal carcinoma tissue.
Using alpha-32P-dCTP labelled human papillomavirus type 16 DNA genome probe (cHPV 16 DNA, cloned and identified from a Chinese cervical invasive carcinoma), 3 HPV 16 genomic relative sequences were detected in 6 biopsies of laryngeal carcinoma. The results showed serious HPV infection in laryngeal carcinoma. This indicates that HPV infection may play an important pathogenetic role in cancer development.
Wang
H
H
Shanxi Cancer Institute, Taiyuan.
Lin
Y C
YC
Kang
X S
XS
Li
G Z
GZ
Li
J
J
Liu
B Y
BY
Qiao
L J
LJ
Ma
K R
KR
D015139:Blotting, Southern; D002277:Carcinoma / Q000382:microbiology*; D015344:DNA Probes, HPV; D004279:DNA, Viral / Q000032:analysis*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000382:microbiology*; D027383:Papillomaviridae / Q000302:isolation & purification*; D014412:Tumor Virus Infections
D015344:DNA Probes, HPV; D004279:DNA, Viral