[Adrenocortical carcinoma: report of a case].
A 24-year-old man visited our hospital complaining of hypertension and headache. Endocrinological findings revealed no abnormalities except for a slight decrease in serum adrenocorticotropic hormone (ACTH), a slight increase in urine 17-ketosteroid (17-KS), and a marked increase in serum pregnenolone. Computed tomography and magnetic resonance imaging revealed a 3 x 3 cm mass in the right adrenal area and I131-aldosterol scintigraphy demonstrated a high absorption of the isotope in the right adrenal area. Vena cavography suggested a 2 x 2 cm tumor thrombus originating in the right adrenal. Under the diagnosis of the right adrenocortical carcinoma, adrenalectomy and removal of the tumor thrombus were performed. Both serum pregnenolone and urine 17-KS returned to the normal level within a week after the operation and blood pressure was well controlled without any medication 3 months after the operation. Thus, the tumor seemed to be endocrinologically active.
Azuma
H
H
Department of Urology, Osaka Medical School.
Okada
S
S
Fukuhara
M
M
Inoue
H
H
Shimizu
A
A
Takasaki
N
N
D015068:17-Ketosteroids / Q000652:urine; D000302:Adrenal Cortex / Q000000981:diagnostic imaging; D000306:Adrenal Cortex Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D000315:Adrenalectomy; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D002277:Carcinoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007457:Iodine Radioisotopes; D008279:Magnetic Resonance Imaging; D008297:Male; D011284:Pregnenolone / Q000097:blood; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed; D014684:Venae Cavae / Q000000981:diagnostic imaging
D015068:17-Ketosteroids; D007457:Iodine Radioisotopes; D011284:Pregnenolone; D000324:Adrenocorticotropic Hormone