title: Aortic/glycosaminoglycans alterations in antiatherogenic action of dietary fiber from unripe banana (Musa paradisiaca).
abstract: Dietary fiber isolated as neutral detergent residue from unripe banana altered the concentration of aortic glycosaminoglycans in rats fed cholesterol free and cholesterol diet. Concentration of hyaluronic acid (9.9%), heparan sulphate (53.4%), chondroitin 4-sulphate (32.6%), chondroitin 6-sulphate (17.9%), dermatan sulphate (18.8%) and heparin (10.1%) increased in the aorta in rats fed cholesterol free diet. In rats fed cholesterol diet, concentration of heparan sulphate (23.3%), chondroitin 4-sulphate (9.8%) and heparin (42.4%) increased while hyaluronic acid showed a decrease (29.7%). The activity of beta-glucuronidase (9.5%) and beta-hexosaminidase (19.7%) decreased in the aorta in rats fed cholesterol free diet and given dietary fiber, while only beta-hexosaminidase (19.3%) decreased in rats fed cholesterol diet.
authors.affiliation: Department of Biochemistry, University of Kerala, Trivandrum.
authors.forename: V
authors.initials: V
authors.lastname: Usha
authors.forename: P L
authors.initials: PL
authors.lastname: Vijayammal
authors.forename: P A
authors.initials: PA
authors.lastname: Kurup
mesh_terms: D000818:Animals; D001011:Aorta / Q000737:chemistry* / Q000201:enzymology; D001161:Arteriosclerosis / Q000517:prevention & control*; D002784:Cholesterol / Q000378:metabolism; D004036:Diet, Atherogenic; D004043:Dietary Fiber / Q000494:pharmacology*; D005638:Fruit; D005966:Glucuronidase / Q000378:metabolism; D006025:Glycosaminoglycans / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D001619:beta-N-Acetylhexosaminidases / Q000378:metabolism
chemical_list: D004043:Dietary Fiber; D006025:Glycosaminoglycans; D002784:Cholesterol; D005966:Glucuronidase; D001619:beta-N-Acetylhexosaminidases