Synthesis and metabolism of fatty acid esters in cultured hepatoma cells exposed to ethanol.
Hepatoma cells in culture synthesized fatty acid ethyl esters when exposed to ethanol at concentrations known to occur in man. Unesterified fatty acids, potentially dangerous to cells, were produced by hydrolysis, and there was significant conversion to cholesterol esters.
D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000378:metabolism*; D004952:Esters; D000431:Ethanol / Q000494:pharmacology*; D005227:Fatty Acids / Q000378:metabolism*; D006801:Humans; D008113:Liver Neoplasms / Q000378:metabolism*; D014407:Tumor Cells, Cultured
D004952:Esters; D005227:Fatty Acids; D000431:Ethanol