Production of anti-tumor-promoting iridoid glucosides in Genipa americana and its cell cultures.
The Genipa americana plant contains geniposide [3] and geniposidic acid [2] in the fruits and geniposidic acid [2] in the leaves. On callus induction, the plant produces tarennoside [1], geniposidic acid [2], and gardenoside [4] in high levels. The leaves of Ge. americana plants redifferentiated from the callus tissues produce 2.
Ueda
S
S
Faculty of Pharmaceutical Sciences, Kyoto University, Japan.
Iwahashi
Y
Y
Tokuda
H
H
D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification / Q000494:pharmacology*; D005960:Glucosides / Q000302:isolation & purification / Q000494:pharmacology*; D004854:Herpesvirus 4, Human / Q000187:drug effects; D006801:Humans; D057888:Iridoid Glucosides; D039823:Iridoids; D011493:Protein Kinase C / Q000187:drug effects; D011714:Pyrans / Q000302:isolation & purification / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic; D005960:Glucosides; D057888:Iridoid Glucosides; D039823:Iridoids; D011714:Pyrans; C007835:geniposide; C058966:geniposidic acid; D011493:Protein Kinase C; C056587:gardenoside