Oligosaccharide-binding molecules on the surface of human hemopoietic and lymphoid cells.
High oligosaccharide specificity for binding carbohydrate probes (biotinylated polyacrylamide with carbohydrates attached) with human hemopoietic and lymphoid cells is shown. Of 15 probes studied those bearing blood group trisaccharides, A and B, bound most intensely. In addition, transformed (leukemic and lymphoid) cells interacted more strongly than normal ones.
Abramenko
I V
IV
Kavetsky Institute for Oncology and Radiobiology Problems, Ukraine Academy of Sciences, Kiev.
Gluzman
D F
DF
Korchagina EYu
Zemlyanukhina
T V
TV
Bovin
N V
NV
D000818:Animals; D002240:Carbohydrate Sequence; D002454:Cell Differentiation; D002460:Cell Line; D002462:Cell Membrane / Q000378:metabolism; D002478:Cells, Cultured; D006801:Humans; D007938:Leukemia / Q000378:metabolism; D007963:Leukocytes, Mononuclear / Q000166:cytology / Q000378:metabolism*; D008214:Lymphocytes / Q000378:metabolism*; D051379:Mice; D015335:Molecular Probes; D008969:Molecular Sequence Data; D009844:Oligosaccharides / Q000378:metabolism*; D014066:Palatine Tonsil / Q000166:cytology / Q000378:metabolism
D015335:Molecular Probes; D009844:Oligosaccharides