title: Design, synthesis, and studies on the structure activity relationships of certain pyrrolo[2,3-d]pyrimidine nucleosides and structurally related analogs as potential antineoplastic and antiviral agents.
authors.affiliation: Department of Medicinal Chemistry, College of Pharmacy, University of Michigan, Ann Arbor.
authors.forename: L B
authors.initials: LB
authors.lastname: Townsend
authors.forename: J C
authors.initials: JC
authors.lastname: Drach
authors.forename: L L
authors.initials: LL
authors.lastname: Wotring
authors.forename: S
authors.initials: S
authors.lastname: Vittori
authors.forename: J S
authors.initials: JS
authors.lastname: Pudlo
authors.forename: E E
authors.initials: EE
authors.lastname: Swayze
authors.forename: P
authors.initials: P
authors.lastname: Gupta
authors.forename: T
authors.initials: T
authors.lastname: Maruyama
authors.forename: N
authors.initials: N
authors.lastname: Saxena
authors.forename: L A
authors.initials: LA
authors.lastname: Coleman
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D000998:Antiviral Agents / Q000138:chemical synthesis*; D002470:Cell Survival / Q000187:drug effects; D003587:Cytomegalovirus / Q000187:drug effects; D015195:Drug Design; D006801:Humans; D007939:Leukemia L1210 / Q000473:pathology; D051379:Mice; D011741:Pyrimidine Nucleosides / Q000138:chemical synthesis* / Q000494:pharmacology; D011758:Pyrroles / Q000138:chemical synthesis* / Q000494:pharmacology; D010948:Viral Plaque Assay
chemical_list: D000970:Antineoplastic Agents; D000998:Antiviral Agents; D011741:Pyrimidine Nucleosides; D011758:Pyrroles