The antidotal activity of the thiol drug diethyldithiocarbamate against N-acetyl-p-benzoquinone imine in isolated hepatocytes.
Lauriault
V V
VV
Faculty of Pharmacy, University of Toronto, Ontario, Canada.
O'Brien
P J
PJ
D000478:Alkylation; D000818:Animals; D000931:Antidotes; D016227:Benzoquinones / Q000037:antagonists & inhibitors* / Q000633:toxicity; D002470:Cell Survival / Q000187:drug effects; D004050:Ditiocarb / Q000494:pharmacology*; D005978:Glutathione / Q000378:metabolism; D007097:Imines / Q000037:antagonists & inhibitors* / Q000633:toxicity; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D000931:Antidotes; D016227:Benzoquinones; D007097:Imines; D004050:Ditiocarb; C028473:N-acetyl-4-benzoquinoneimine; D005978:Glutathione