A rational system for classifying and denominating adenovirus genome types.
We propose to classify "genome types" of human adenoviruses in the same way as the "genomic clusters" defined by Li and Wadell, i.e. groups of closely related DNA variants of a given serotype named by the use of indices, P (standing for prototype) a, b etc. Variants within the genome type are named by letter-number indices (p1, p2; a1, a2 etc.). The percentage of comigrating restriction fragments and common restriction sites is significantly higher in variants than between genome types. The new naming system is applicable to adenoviruses from 5 subgenera, but requires additional work for subgenus C strains. Renaming is required mainly for adenovirus 7.
Wigand
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R
Abteilung für Virologie, Universitätskliniken, Homburg/Saar, Germany.
Adrian
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T
D000260:Adenoviruses, Human / Q000145:classification* / Q000235:genetics; D004262:DNA Restriction Enzymes; D004279:DNA, Viral / Q000145:classification / Q000235:genetics; D005814:Genes, Viral; D014644:Genetic Variation; D012703:Serotyping
D004279:DNA, Viral; D004262:DNA Restriction Enzymes