The major glycoprotein of Sendai virus is dispensable for efficient virus particle budding.
A temperature-sensitive mutant of Sendai virus, ts271, when grown at restrictive temperature is known to produce virions lacking integral haemagglutinin-neuraminidase (HN). In this study, it is shown that the transmembrane-cytoplasmic tail of HN is not detected either. This apparent complete lack of HN does not affect budding efficiency.
Stricker
R
R
Department of Microbiology, University of Geneva, Medical School, Switzerland.
Roux
L
L
D002460:Cell Line; D015707:HN Protein / Q000502:physiology*; D010222:Parainfluenza Virus 1, Human / Q000502:physiology*; D013696:Temperature; D014771:Virion / Q000502:physiology*
D015707:HN Protein