title: High prevalence of hepatitis C virus antibodies in a local haemophiliac population.
abstract: Non-A, non-B hepatitis is common among individuals with clotting factor deficiencies who have had multiple exposures to replacement concentrate. Newly introduced screening tests for hepatitis C virus antibody make it possible to determine the prevalence of this entity in defined populations. In 68 haemophiliac patients attending the Groote Schuur Hospital clinic, 44 were shown to be positive (65%). There was no significant correlation between seropositivity for this agent and severity of the bleeding disorder, age or elevation of the liver enzyme values.
authors.affiliation: Leukaemia Centre, University of Cape Town.
authors.forename: J M
authors.initials: JM
authors.lastname: du Toit
authors.forename: N S
authors.initials: NS
authors.lastname: Brink
authors.forename: A R
authors.initials: AR
authors.lastname: Bird
authors.forename: S C
authors.initials: SC
authors.lastname: Robson
authors.forename: P
authors.initials: P
authors.lastname: Jacobs
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006467:Hemophilia A / Q000150:complications / Q000276:immunology*; D016174:Hepacivirus / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000032:analysis*; D006526:Hepatitis C / Q000150:complications / Q000635:transmission; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy; D065227:Transfusion Reaction
chemical_list: D006508:Hepatitis Antibodies