[Significance of narrow frequency bands of the EEG spectrum for demonstrating the effect of diazepam in patients with borderline mental disorders].
A study was made of the effect of the single test dose of diazepam (10 mg, i. m.) and continuous drug therapy on the narrow spectral bands of the EEG in the range of 0.4-30.0 Hz. A relationship was demonstrated between the pattern of EEG changes and individual intensity in patients of the clinical manifestations of activation, tranquilization and sedation as well as the total efficacy of continuous therapy, disease standing and previous treatment. The frequencies of alpha-rhythm were found to be more informative for the reflection of the clinico-electrophysiological correlations established.
Bochkarev
V K
VK
Serebriakova
T V
TV
D000328:Adult; D000513:Alpha Rhythm / Q000187:drug effects; D002540:Cerebral Cortex / Q000187:drug effects* / Q000503:physiopathology; D003975:Diazepam / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004569:Electroencephalography / Q000187:drug effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009497:Neurotic Disorders / Q000188:drug therapy* / Q000503:physiopathology; D013997:Time Factors
D003975:Diazepam
Znachenie uzkikh chastotnykh polos spektra EEG dlia kharakteristiki deĭstviia diazepama u bol'nykh s pogranichnymi psikhicheskimi rasstroĭstvami.