[Detection of movement disorders in newborn infants by using infants' blood serum in experimental models].
A method of early diagnosis of motor disorders of the central genesis in neonates within the first to the third days of life was elaborated in experimental models for estimating the status of the motor apparatus. The experiments were made on spinal (Th3-Th5) albino noninbred rats used as recipients, in which spontaneous and electric stimulation-induced EMG activity of the antagonists muscles of the hind limbs was recorded before and after intralumbar administration of donors' blood serum. The presence of motor pathology in a donor child is judged from the changes in the EMG parameters after administration of blood serum. The method enables revealing motor disorders in neonates even in cases where the clinical examination does not provide any conclusive answer.
Bogdanov
O V
OV
Avaliani
T V
TV
D000818:Animals; D001790:Blood Physiological Phenomena; D004576:Electromyography; D006614:Hindlimb / Q000502:physiology; D006801:Humans; D007231:Infant, Newborn; D007278:Injections, Spinal; D008954:Models, Biological; D009123:Muscle Hypotonia / Q000097:blood / Q000175:diagnosis* / Q000503:physiopathology; D009132:Muscles / Q000502:physiology / Q000503:physiopathology*; D051381:Rats; D012018:Reflex / Q000502:physiology*
Vyiavlenie dvigatel'nykh rasstroĭstv v period novorozhdennosti priemami biotestirovaniia syvorotki krovi deteĭ na éksperi- mental'nykh modeliakh.