title: [The ratio of sex hormone production by the ovaries and the adrenal cortex in different phases of the rat estrous cycle].
abstract: The biosynthesis of estradiol and testosterone was found to occur mainly in the ovaries (4-5 and 10-20 times more than in the adrenals during diestrus and proestrus, resp.). Estron and androstendion were produced equally in both glands. The estrogens and androgens were found to act as synergists in the stimulation of biosynthetic processes in the uterus. Their level in peripheral blood reflects less fully the character of hormonal function of the ovaries than study of these steroids in the incubates of the ovaries. The biosynthesis of progesterone in adrenals exceeds 2-3-fold that in the ovaries. No changes on production of this hormone depending on the cycle phase, were found.
authors.forename: M G
authors.initials: MG
authors.lastname: Stepanov
authors.forename: O N
authors.initials: ON
authors.lastname: Savchenko
mesh_terms: D000302:Adrenal Cortex / Q000737:chemistry; D000305:Adrenal Cortex Hormones / Q000032:analysis / Q000096:biosynthesis*; D000814:Aniline Compounds / Q000494:pharmacology*; D000818:Animals; D002940:Circadian Rhythm / Q000502:physiology; D004971:Estrus / Q000502:physiology*; D005260:Female; D012739:Gonadal Steroid Hormones / Q000032:analysis / Q000096:biosynthesis*; D006834:Hydrazines / Q000494:pharmacology*; D010053:Ovary / Q000737:chemistry / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000305:Adrenal Cortex Hormones; D000814:Aniline Compounds; D012739:Gonadal Steroid Hormones; D006834:Hydrazines; C034343:4-aminobenzhydrazide
vernacular_title: Sootnoshenie produktsii polovykh gormonov iaichnikami i koroĭ nadpochechnikov v razlichnye fazy éstral'nogo tsikla u krys.