title: First report of an infectious bursal disease outbreak in a vaccinated chicken flock in Anambra State, Nigeria.
abstract: Infectious bursal disease was reported in a flock of 7-week old vaccinated chickens. Clinical findings and post-mortem changes were classical as well as the microscopic pathology of the bursa. Bursal homogenates from dead birds were positive for IBD virus antigen in agar gel diffusion test (AGDT). Convalescent sera obtained from birds 14 days following the onset of clinical signs were also positive for IBD virus antibody in AGDT. Seven-week old susceptible birds, each infected i/m with 0.1 ml of a bursal preparation from the outbreak, showed clinical signs of IBD on the 3rd day and were all dead by the 6th day. Their bursae were also positive for IBD virus antigen in AGDT. This is the first recorded outbreak of IBD in Southern Nigeria following inoculation with a locally produced vaccine.
authors.affiliation: National Veterinary Research Institute, Vom, Nigeria.
authors.forename: O
authors.initials: O
authors.lastname: Onunkwo
authors.forename: J O
authors.initials: JO
authors.lastname: Okoye
mesh_terms: D000818:Animals; D002645:Chickens; D004196:Disease Outbreaks; D007243:Infectious bursal disease virus; D009549:Nigeria / Q000453:epidemiology; D011201:Poultry Diseases / Q000453:epidemiology*; D012088:Reoviridae Infections / Q000662:veterinary*; D014611:Vaccination