[Somatosensory evoked potentials in the sleep-wakefulness cycle in healthy subjects and narcolepsy patients].
Studies of somatosensory evoked potentials (SSEPs) were conducted in various functional states of sleep-alertness cycle (relaxed alertness, 2-nd and delta-stages of slow sleep, rapid sleep) in 7 healthy subjects and 8 patients with polysymptom narcolepsy. Integrated amplitude (IA) was calculated in poststimulus intervals, accordingly to SSEPs division into groups of early (20-80 ms), mean (80-200 ms) and late (200-400 ms) components. It has been shown that in patients with polysymptom narcolepsy IA of all SSEPs components in alertness was lower than in healthy subjects; during sleep higher IA values of earlier components were found in comparison with healthy subjects and lower values--of later negative wave at slow sleep. Psychophysiological interpretation of high amplitude negative shift in the area of late SSEPs components during slow sleep is suggested.
Zenkov
L R
LR
Razumov
V M
VM
Iakhno
N N
NN
Petrenko
A P
AP
D000328:Adult; D004569:Electroencephalography / Q000295:instrumentation / Q000379:methods; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D006801:Humans; D009290:Narcolepsy / Q000503:physiopathology*; D011930:Reaction Time / Q000502:physiology; D012016:Reference Values; D012890:Sleep / Q000502:physiology*; D012894:Sleep Stages / Q000502:physiology; D014851:Wakefulness / Q000502:physiology*
Somatosensornye vyzvannye potentialy v tsikle son--bodrstvovanie u zdorovykh ispytuemykh i bol'nykh narkolepsieĭ.