title: Establishment of clonal cell lines, with or without cartilage phenotypes, from a hamster mesenchymal chondrosarcoma.
abstract: A hamster mesenchymal chondrosarcoma was found in the soft tissues of the cheek pouch and has been successfully transplanted. The tumor was composed principally of two cell types: poorly differentiated mesenchymal cells and focal areas of cells in islands showing cartilaginous differentiation. The clonal cell lines, MCS-1 and MCS-8 which closely correspond to the respective cell types in the original tumor were also established. MCS-1 cells formed an undifferentiated sarcoma in the subcutaneous layer of nude mice and MCS-8 cells formed a chondrosarcoma of a common type.
authors.affiliation: 1st Department of Pathology, Niigata University School of Medicine, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Fujisawa
authors.forename: N L
authors.initials: NL
authors.lastname: Sato
authors.forename: T
authors.initials: T
authors.lastname: Motoyama
mesh_terms: D000818:Animals; D002356:Cartilage / Q000473:pathology; D002813:Chondrosarcoma / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D002999:Clone Cells / Q000378:metabolism / Q000473:pathology; D003094:Collagen / Q000378:metabolism; D006224:Cricetinae; D003412:Cricetulus; D007621:Karyotyping; D010641:Phenotype; D012983:Soft Tissue Neoplasms / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D014407:Tumor Cells, Cultured / Q000378:metabolism / Q000473:pathology
chemical_list: D003094:Collagen