Class-3 porin protein of Neisseria meningitidis: cloning and structure of the gene.
The gene coding for the class-3 protein of Neisseria meningitidis was cloned and sequenced. The deduced amino acid (aa) sequence was highly homologous (50-78%) to those of other neisserial porin proteins. Alignment of the aa sequence of five neisserial porin proteins pinpointed several regions of identity or near identity. These are assumed to be membrane-spanning beta-strands. A comparison of the homologies between these neisserial porins showed that the class-3 protein is most closely related to the Neisseria gonorrhoeae P1A protein.
Butcher
S
S
Molecular Biology Program, National Public Health Institute, Helsinki, Finland.
Sarvas
M
M
Runeberg-Nyman
K
K
D000595:Amino Acid Sequence; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D001483:Base Sequence; D003001:Cloning, Molecular; D008969:Molecular Sequence Data; D009344:Neisseria gonorrhoeae / Q000235:genetics; D009345:Neisseria meningitidis / Q000235:genetics*; D018272:Porins; D016415:Sequence Alignment; D012689:Sequence Homology, Nucleic Acid
D001425:Bacterial Outer Membrane Proteins; D018272:Porins