Hypercholesterolaemia alters platelet reactivity and the antihypertensive effect of nitrendipine.
Le Quan Sang
K H
KH
Department of Pharmacology, CNRS 161670, CHU-Necker, Paris, France.
Mazeaud
M
M
Levenson
J
J
Del Pino
M
M
Pithois-Merli
I
I
Simon
A
A
Devynck
M A
MA
D001792:Blood Platelets / Q000737:chemistry / Q000187:drug effects* / Q000502:physiology; D001794:Blood Pressure / Q000187:drug effects; D002118:Calcium / Q000032:analysis; D002784:Cholesterol / Q000097:blood; D000242:Cyclic AMP / Q000032:analysis; D003600:Cytosol / Q000737:chemistry; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications*; D006973:Hypertension / Q000097:blood* / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology; D008560:Membrane Fluidity; D008875:Middle Aged; D009568:Nitrendipine / Q000627:therapeutic use*; D010974:Platelet Aggregation / Q000187:drug effects
D002784:Cholesterol; D009568:Nitrendipine; D000242:Cyclic AMP; D002118:Calcium