title: Treatment of deep mycoses with itraconazole.
abstract: Four patients with deep mycoses were treated with itraconazole. Two patients had chromoblastomycosis, one patient each had aspergillosis and Rhinofacial zygomycosis. These patients were either resistant to or showed poor response to Amphotericin B and/or ketoconazole. After the initial clinical and mycological evaluation, itraconazole was given in a daily dose of 200 mg orally. All patients responded to the drug very well. No adverse effects attributable to itraconazole were detected.
authors.affiliation: Department of Dermatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: B
authors.initials: B
authors.lastname: Kumar
authors.forename: I
authors.initials: I
authors.lastname: Kaur
authors.forename: A
authors.initials: A
authors.lastname: Chakrabarti
authors.forename: V K
authors.initials: VK
authors.lastname: Sharma
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D000995:Antitubercular Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000188:drug therapy*; D002648:Child; D002862:Chromoblastomycosis / Q000188:drug therapy*; D004352:Drug Resistance, Microbial; D006801:Humans; D017964:Itraconazole; D007654:Ketoconazole / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000188:drug therapy*
chemical_list: D000935:Antifungal Agents; D000995:Antitubercular Agents; D017964:Itraconazole; D000666:Amphotericin B; D007654:Ketoconazole