Serologic evidence of coronavirus infection in New York and New England dairy cattle with winter dysentery.
Acute and convalescent sera were collected from 8 dairy herds with classic clinical features of winter dysentery. An enzyme-linked immunosorbent assay was used to measure coronavirus antibody titers, employing calf diarrhea coronavirus as antigen. Twenty-two of the 35 animals tested (63%) showed a greater than or equal to 4-fold seroconversion. Adult cattle in all 8 herds seroconverted. These findings complement previously reported immunoperoxidase and electron microscopic evidence, suggesting an etiologic role for an enteric coronavirus in this disease.
Van Kruiningen
H J
HJ
Department of Pathobiology, University of Connecticut, Storrs 06269.
Castellano
V P
VP
Torres
A
A
Sharpee
R L
RL
D000208:Acute Disease; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology*; D003237:Connecticut / Q000453:epidemiology; D003332:Coronaviridae / Q000276:immunology*; D003333:Coronaviridae Infections / Q000453:epidemiology / Q000662:veterinary*; D003967:Diarrhea / Q000453:epidemiology / Q000662:veterinary; D004403:Dysentery / Q000453:epidemiology / Q000662:veterinary*; D004797:Enzyme-Linked Immunosorbent Assay; D009518:New York / Q000453:epidemiology
D000914:Antibodies, Viral