[The micro- and macrovascular reactivity of the arterial bed in renovascular hypertension in rats].
In rats with experimental hypertension, mesenteric artery revealed a hypersensitivity to noradrenaline whereas aorta did not differ from normal values of this parameter. The sensitivity of femoral artery was lowered. The microarterioles of hypertensive animals manifested a lower sensitivity to noradrenaline as well. This data suggests that arterial vessels manifest a regional heterogeneity of their functional properties in chronic birenal renovascular hypertension.
Balashov
N V
NV
Soltitskiĭ
V V
VV
Serebriakova
N B
NB
D000818:Animals; D001011:Aorta / Q000187:drug effects / Q000503:physiopathology; D001158:Arteries / Q000187:drug effects / Q000503:physiopathology*; D002908:Chronic Disease; D004305:Dose-Response Relationship, Drug; D005263:Femoral Artery / Q000187:drug effects / Q000503:physiopathology; D006978:Hypertension, Renovascular / Q000503:physiopathology*; D008297:Male; D008638:Mesenteric Arteries / Q000187:drug effects / Q000503:physiopathology; D008833:Microcirculation / Q000187:drug effects / Q000503:physiopathology; D009638:Norepinephrine / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains
D009638:Norepinephrine
Reaktivnost' mikro- i makrososudov arterial'nogo rusla pri renovaskuliarnoĭ gipertonii u krys.