[Protection of beta-adrenoreceptors of the rat brain during emotional-pain stress by oxidants of the steric hindrance class of phenols].
Adaptogenic properties of a new antioxidant-isoquinoline derivative of hindered phenol class under pain-emotional stress have been investigated. This new antioxidant was shown to have stress-protective effects, i.e. it stabilizes cerebral beta-adrenoreceptors, inhibits lipid peroxidation and stimulates anti-radical defense systems in the brain and serum, as well as normalizes vegetative functions in rats.
Libe
M L
ML
Brusovanik
V I
VI
Ukhin
L Iu
LIu
Levshina
I P
IP
Guliaeva
N V
NV
Erin
A N
AN
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001921:Brain / Q000187:drug effects*; D005260:Female; D007546:Isoquinolines / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects; D010146:Pain / Q000503:physiopathology; D051381:Rats; D011943:Receptors, Adrenergic, beta / Q000187:drug effects*; D013315:Stress, Psychological / Q000188:drug therapy / Q000503:physiopathology*
D000975:Antioxidants; D007546:Isoquinolines; D011943:Receptors, Adrenergic, beta; C039109:isoquinoline
Zashchita beta-adrenoretseptorov mozga krys pri émotsional'no-bolevom stresse antioksidantom klassa prostranstvenno-zatrudnennykh fenolov.