Depicting topology and handedness in jellyroll structures.
The jellyroll structure is a special case of the Greek key topology and, to date, has only been observed in complete form in one of its four possible arrangements. Like other elements of super-secondary structure involving the beta-strand (e.g. the beta alpha beta unit) the known structure forms a right-handed superhelix. The possibility of losing such tertiary information and other problems associated with representing these structures by two-dimensional topology diagrams are discussed. A series of rules are presented which allow this three-dimensional information to be represented in two-dimensional topology diagrams from which the handedness of a jellyroll structure can be determined.
Stirk
H J
HJ
Department of Biochemistry and Molecular Biology, University College, London, UK.
Woolfson
D N
DN
Hutchinson
E G
EG
Thornton
J M
JM
D011487:Protein Conformation