title: [The efficacy of glucosamine in treating complicated hyperreactive experimental myocardial infarct].
abstract: The effect of glucosamine hydrochloride on the course of complicated hyperreactive myocardial infarction in dogs was studied. Glucosamine contributed to the restoration of reactivity in the animals. The reactivity became corresponding for normoreactive myocardial infarction. Glucosamine normalized carbohydrate and protein metabolism in the necrosis zone, cAMP and cGMP and also their ratio that led to healing by postinfarction scar, and in none of the cases the heart aneurysm developed. The optimizing healing of hyperreactive myocardial infarction under the influence of glucosamine is mediated through the mechanisms of reactivity and the regulation of metabolic processes.
authors.forename: V N
authors.initials: VN
authors.lastname: Sokrut
authors.forename: I A
authors.initials: IA
authors.lastname: Zupanets
authors.forename: N I
authors.initials: NI
authors.lastname: Iabluchanskiĭ
authors.forename: S M
authors.initials: SM
authors.lastname: Drogovoz
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000097:blood; D000818:Animals; D004247:DNA / Q000096:biosynthesis; D004195:Disease Models, Animal; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D004837:Epinephrine / Q000097:blood; D005944:Glucosamine / Q000627:therapeutic use*; D006854:Hydrocortisone / Q000097:blood; D007328:Insulin / Q000097:blood; D008070:Lipopolysaccharides; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D009712:Nucleotides, Cyclic / Q000097:blood; D011749:Pyrogens; D013997:Time Factors
chemical_list: D007328:Insulin; D008070:Lipopolysaccharides; D009712:Nucleotides, Cyclic; D011749:Pyrogens; C009136:pyrogenal; D000324:Adrenocorticotropic Hormone; D004247:DNA; D005944:Glucosamine; D006854:Hydrocortisone; D004837:Epinephrine
vernacular_title: Effektivnost' gliukozamina v lechenii oslozhnennogo giperreaktovnogo éksperimental'nogo infarkta miokarda.