title: Breast cancer developing after chemotherapy for osteosarcoma: a case report.
abstract: A 24-year-old patient who developed breast cancer 16 years after chemotherapy for osteosarcoma is presented. She had no family history of cancer. She had also not had radiotherapy. She had been given chemotherapy consisting of VAOMT (vincristine 10.2 mg, cyclophosphamide 900 mg, mitomycin C 15.2 mg, chromomycin A3 25.8 mg) pre- and post-operatively in the treatment of her osteosarcoma. Careful long-term follow-up is required after treatment of malignant neoplasms because there is a possibility of developing a second malignancy.
authors.affiliation: Department of Surgery, Tochigi Cancer Center, Utsunomiya.
authors.forename: T
authors.initials: T
authors.lastname: Ikeda
authors.forename: C
authors.initials: C
authors.lastname: Sekiguchi
authors.forename: K
authors.initials: K
authors.lastname: Shimamura
authors.forename: I
authors.initials: I
authors.lastname: Ozawa
authors.forename: T
authors.initials: T
authors.lastname: Inada
authors.forename: S
authors.initials: S
authors.lastname: Hishinuma
authors.forename: H
authors.initials: H
authors.lastname: Shimizu
authors.forename: K
authors.initials: K
authors.lastname: Kotake
authors.forename: Y
authors.initials: Y
authors.lastname: Ogata
authors.forename: Y
authors.initials: Y
authors.lastname: Koyama
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000139:chemically induced / Q000473:pathology / Q000601:surgery; D014128:Chromomycin A3 / Q000008:administration & dosage; D003520:Cyclophosphamide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007717:Knee; D016685:Mitomycin / Q000008:administration & dosage; D016609:Neoplasms, Second Primary / Q000139:chemically induced* / Q000601:surgery; D012516:Osteosarcoma / Q000188:drug therapy*; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D016685:Mitomycin; D014750:Vincristine; D003520:Cyclophosphamide; D014128:Chromomycin A3