[Second solid tumors in childhood. Review based on three cases].
As children with cancer survive longer, the incidence of second malignant neoplasms has increased considerably. We describe here three cases of second solid tumors after 12, 8 and 2 years of initial diagnosis of cancer: one osteosarcoma of left maxilla in a previously treated child with bilateral retinoblastoma, a temporal astrocytoma associated with acute lymphoblastic leukemia and a glioblastoma multiforme in a girl with neurofibromatosis de Von Recklinghausen, after Non Hodgkin lymphoma, respectively. We review the literature about the influence of genetic, immunologic and therapeutic factors involved in the appearance of these second tumors.
Astigarraga Aguirre
I
I
Unidad de Oncología Infantil, Departamento de Pediatría, Hospital de Cruces de Baracaldo, Vizaya.
Navajas Gutiérrez
A
A
Rivera Aranda
A
A
Moya Calderón
E
E
Bezanilla Regato
J L
JL
D001254:Astrocytoma / Q000235:genetics / Q000276:immunology / Q000628:therapy; D002648:Child; D005260:Female; D005909:Glioblastoma / Q000235:genetics / Q000276:immunology / Q000628:therapy; D006689:Hodgkin Disease / Q000235:genetics / Q000276:immunology / Q000628:therapy; D006801:Humans; D007223:Infant; D008228:Lymphoma, Non-Hodgkin / Q000235:genetics / Q000276:immunology / Q000628:therapy; D008297:Male; D008441:Maxillary Neoplasms / Q000235:genetics / Q000276:immunology / Q000628:therapy; D016609:Neoplasms, Second Primary / Q000235:genetics* / Q000276:immunology / Q000628:therapy; D009456:Neurofibromatosis 1 / Q000235:genetics / Q000276:immunology / Q000628:therapy; D012516:Osteosarcoma / Q000235:genetics / Q000276:immunology / Q000628:therapy; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics / Q000276:immunology / Q000628:therapy; D012175:Retinoblastoma / Q000235:genetics / Q000276:immunology / Q000628:therapy
Segundos tumores sólidos en la infancia. Revisión a propósito de tres casos.