title: Immunogenicity trial of inactivated hepatitis A virus vaccine in human volunteers.
abstract: An inactivated hepatitis A virus (HAV) vaccine was tested on a group of human adult volunteers. The vaccine was administered subcutaneously, and a control group received a placebo (aluminium hydroxide). The vaccine was found to be relatively well tolerated and non-reactogenic, and levels of anti-HAV were comparable to those in other studies.
authors.affiliation: Institute of Poliomyelitis and Viral Encephalitides, Moscow State Medical Institute, USSR.
authors.lastname: Kusov YuYu
authors.forename: L B
authors.initials: LB
authors.lastname: Elbert
authors.forename: I V
authors.initials: IV
authors.lastname: Nelga
authors.forename: G K
authors.initials: GK
authors.lastname: Grishina
authors.forename: O A
authors.initials: OA
authors.lastname: Dunaevski
authors.forename: N V
authors.initials: NV
authors.lastname: Kharin
authors.lastname: Maslov YuN
authors.forename: S G
authors.initials: SG
authors.lastname: Drozdov
authors.forename: M S
authors.initials: MS
authors.lastname: Balayan
mesh_terms: D000293:Adolescent; D000328:Adult; D000536:Aluminum Hydroxide; D005260:Female; D035922:Hepatitis A Antibodies; D006508:Hepatitis Antibodies / Q000096:biosynthesis*; D006507:Hepatovirus / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014611:Vaccination / Q000009:adverse effects; D014613:Vaccines, Attenuated / Q000009:adverse effects / Q000276:immunology; D014761:Viral Hepatitis Vaccines / Q000009:adverse effects / Q000276:immunology*
chemical_list: D035922:Hepatitis A Antibodies; D006508:Hepatitis Antibodies; D014613:Vaccines, Attenuated; D014761:Viral Hepatitis Vaccines; D000536:Aluminum Hydroxide