[Familial colonic polyposis and malignant transformation: preventive colectomy in childhood?].
Familial polyposis coli is a classical premalignant disease. Malignancy has been observed as early as the 2nd decade of life. The probability of the development of colorectal cancer rises with age. The problem of prophylactic colectomy in childhood and adolescence is discussed using the example of two sisters whose father died of colorectal cancer at the age of 32.
Roth
H
H
Kinderchirurg. Abtlg. d. Chirurg. Univ.-Klinik Heidelberg, Bundesrepublik Deutschland.
Daum
R
R
Benz
G
G
von Herbay
A
A
D011125:Adenomatous Polyposis Coli / Q000235:genetics / Q000517:prevention & control* / Q000601:surgery*; D002648:Child; D003082:Colectomy; D005260:Female; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology; D010375:Pedigree; D011230:Precancerous Conditions / Q000235:genetics / Q000517:prevention & control* / Q000601:surgery*; D012307:Risk Factors
Familiäre Polyposis Coli und Maligne Entartung: Prophylaktische Kolektomie im Kindesalter?