title: Collagenase of Clostridium perfringens type A: degradation of human complement component C1q.
abstract: The semipurified collagenases from Clostridium perfringens type A strains 2-Cli and ATCC 13124, both characterized by molecular weights of 79.4 kilodaltons, partially degraded purified human complement (C) component C1q. The following purified human serum proteins were refractory: C components C3, C4, C5, C6, C7, C8, and C9; immunoglobulin (Ig)A (from colostrum), IgG, and IgM; alpha 2-macroglobulin, haptoglobin, and C-reactive protein.
authors.affiliation: Institut für Medizinische Mikrobiologie und Hygiene, Universität des Saarlandes, Homburg/Saar.
authors.forename: U
authors.initials: U
authors.lastname: Wolf
authors.forename: D
authors.initials: D
authors.lastname: Bauer
authors.forename: W H
authors.initials: WH
authors.lastname: Traub
mesh_terms: D015153:Blotting, Western; D003016:Clostridium perfringens / Q000201:enzymology*; D015922:Complement C1q / Q000378:metabolism*; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007526:Isoelectric Point; D003012:Microbial Collagenase / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D008970:Molecular Weight
chemical_list: D015922:Complement C1q; D003012:Microbial Collagenase