[The in vitro inhibitory effect of sodium selenite on complement activation].
Sodium selenite exerts a marked inhibiting effect on the hemolysis induced by complement fixation. The results of rocket immunoelectrophoresis tests for the activated fragments C3d and C4d show that sodium selenite inhibits complement activation through the alternative pathway.
Li
B
B
Institute of Basic Medical Sciences, Beijing.
D003167:Complement Activation / Q000187:drug effects*; D015933:Complement C3d / Q000187:drug effects; D003181:Complement C4 / Q000187:drug effects; D015935:Complement C4b; D006461:Hemolysis / Q000187:drug effects; D006801:Humans; D010446:Peptide Fragments / Q000187:drug effects; D012643:Selenium / Q000494:pharmacology*; D018038:Sodium Selenite
D003181:Complement C4; D010446:Peptide Fragments; D015933:Complement C3d; D015935:Complement C4b; C032261:complement C4d; D012643:Selenium; D018038:Sodium Selenite