title: [Study of luminol-dependent chemiluminescence of peripheral blood in acute pneumonia].
abstract: Active oxygen forms (AOF) were measured in whole peripheral blood of 40 acute pneumonia patients using luminol-dependent spontaneous chemiluminescence (LDSC) and luminol-dependent zymosan-stimulated chemiluminescence (LDZSC) in the time course of the disease. Within week 1 of the disease both LDSC and LDZSC were increased in the majority of patients whereas low levels of AOF production served a predictor of poor prognosis in relation to acute pneumonia complications. If high intensity of LDSC and LDZSC persisted for 2 weeks pneumonia was likely to resolve completely though complications were possible. Protracted disease was associated with 3-week high AOF production. The data give evidence for possible application of LDSC and LDZSC of whole peripheral blood to predict complications and incomplete resolution of acute pneumonia.
authors.forename: N V
authors.initials: NV
authors.lastname: Baltiĭskaia
authors.forename: L G
authors.initials: LG
authors.lastname: Korkina
authors.forename: I I
authors.initials: II
authors.lastname: Selivanov
authors.forename: I A
authors.initials: IA
authors.lastname: Solov'eva
authors.forename: N G
authors.initials: NG
authors.lastname: Chupeeva
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D005260:Female; D005609:Free Radicals; D006801:Humans; D006861:Hydrogen Peroxide / Q000097:blood*; D006878:Hydroxides / Q000097:blood*; D008163:Luminescent Measurements; D008165:Luminol; D008297:Male; D011014:Pneumonia / Q000097:blood* / Q000175:diagnosis; D013481:Superoxides / Q000097:blood*
chemical_list: D005609:Free Radicals; D006878:Hydroxides; D013481:Superoxides; D008165:Luminol; C031356:hydroxide ion; D006861:Hydrogen Peroxide
vernacular_title: Issledovanie liuminolzavisimoĭ khemiliuminestsentsii periferi- cheskoĭ krovi pri ostroĭ pnevmonii.