title: Orthotopic liver transplantation in the management of end stage liver disease: the University of Vienna experience.
abstract: Two hundred and eight orthotopic liver transplantations (OLT) were performed in 191 patients at the I Department of Surgery, University of Vienna from 1982-1990. The most frequent indications were hepatocellular carcinoma, alcoholic cirrhosis, posthepatic cirrhosis, primary biliary cirrhosis, and fulminant hepatic failure. Patients with malignancy constituted 33.8% of cases. The overall results showed a 64% one-year and 58% two-year survival; best results were seen in patients with primary biliary cirrhosis and the poorest long-term results were in malignancy. There were 23 postoperative deaths (11%). Primary non-function was seen in 14 (7%) cases; acute rejection episodes were seen in 62% of patients. The presence of a well organised cadaver organ procurement system in eastern Austria with upto 41 donors per million population per year ensures that the 57% growth rate in OLT achieved in 1990 will be maintained with even better results.
authors.affiliation: Erste Chirurgische Universitaetsklinik (I Department of Surgery), University of Vienna, Austria.
authors.forename: D F
authors.initials: DF
authors.lastname: Mirza
authors.forename: P
authors.initials: P
authors.lastname: Goetzinger
authors.forename: R
authors.initials: R
authors.lastname: Fuegger
authors.forename: P
authors.initials: P
authors.lastname: Wamser
authors.forename: R
authors.initials: R
authors.lastname: Steininger
authors.forename: F
authors.initials: F
authors.lastname: Muehlbacher
mesh_terms: D001317:Austria; D006528:Carcinoma, Hepatocellular / Q000401:mortality / Q000601:surgery; D002908:Chronic Disease; D006084:Graft Rejection / Q000276:immunology; D006085:Graft Survival / Q000276:immunology; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000401:mortality / Q000601:surgery; D008107:Liver Diseases / Q000401:mortality / Q000601:surgery*; D008113:Liver Neoplasms / Q000401:mortality / Q000601:surgery; D016031:Liver Transplantation / Q000401:mortality