title: MR differentiation of hepatic haemangioma and hepatocellular carcinoma: value of delayed-phase Gd-DTPA enhanced images.
abstract: The efficacy of three different approaches (precontrast and delayed-phase postcontrast T1-weighted (T1-W) images, measurement of T2 value, and dynamic FLASH imaging) for differentiation between hepatic haemangiomas and hepatocellular carcinomas, was compared. Most haemangiomas (89%) showed iso- or hypointensity on precontrast T1-W images and hyperintensity on delayed-phase postcontrast T1-W images. By using both pre/postcontrast T1-W images and T2 measurement, 30 out of 32 lesions (94%) were correctly differentiated. The dynamic FLASH imaging did not significantly improve the overall accuracy although it played a critical role in a few problematic cases. It is concluded that the combination of pre/postcontrast T1-W images is a promising approach for differentiation of small hepatic tumours, and plays a complementary role with T2 measurement.
authors.affiliation: Department of Radiology, University of Tokyo.
authors.forename: Y
authors.initials: Y
authors.lastname: Okada
authors.forename: Y
authors.initials: Y
authors.lastname: Itai
authors.forename: K
authors.initials: K
authors.lastname: Ohtomo
authors.forename: T
authors.initials: T
authors.lastname: Kokubo
authors.forename: H
authors.initials: H
authors.lastname: Yoshida
authors.forename: Y
authors.initials: Y
authors.lastname: Sasaki
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis*; D003287:Contrast Media; D003937:Diagnosis, Differential; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006391:Hemangioma / Q000175:diagnosis*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008113:Liver Neoplasms / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid; D013997:Time Factors
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA