title: [Creatine phosphokinase isoenzymes (CK BB) of the brain in peripheral tissues in schizophrenia].
abstract: The activity and content of the brain isoenzyme of creatine phosphokinase-BB (CPK-BB) were investigated in the peripheral tissues containing this isoenzyme (in the small intestine and heart) in health and schizophrenia. The decrease of CPK-BB activity and content in schizophrenic brain was shown before. The present work demonstrates the reduction of CPK-BB activity and concentration not only in the brain of mental patients but also in the intestine and heart tissues. A high correlation was discovered between the CPK-BB level in the brain and in the intestine of schizophrenic patients (r = 0.85).
authors.forename: M V
authors.initials: MV
authors.lastname: Aksenova
authors.forename: N S
authors.initials: NS
authors.lastname: Karaseva
authors.forename: G Sh
authors.initials: GSh
authors.lastname: Burbaeva
mesh_terms: D001921:Brain / Q000201:enzymology*; D003402:Creatine Kinase / Q000737:chemistry / Q000172:deficiency / Q000378:metabolism*; D006801:Humans; D007421:Intestine, Small / Q000201:enzymology* / Q000473:pathology; D007527:Isoenzymes; D008875:Middle Aged; D009206:Myocardium / Q000201:enzymology* / Q000473:pathology; D012016:Reference Values; D012559:Schizophrenia / Q000201:enzymology* / Q000473:pathology
chemical_list: D007527:Isoenzymes; D003402:Creatine Kinase
vernacular_title: Mozgovaia izoforma kreatinfosfokinazy (KFK BB) v perifericheskikh tkaniakh pri shizofrenii.