title: [Thyrotoxic periodic paralysis and Graves' disease. Description of an HLA-CW7-positive case].
abstract: Thyrotoxic periodic paralysis is an uncommon complication of hyperthyroidism, more frequent in Oriental populations and in male than in female subjects. Electron microscopic investigations have shown characteristic degenerative changes of muscle fiber. In this study the sequence of pathophysiologic events proposed by the literature is illustrated and a case of thyrotoxic periodic paralysis in a HLA-CW7 positive patient affected by Graves' disease is reported.
authors.affiliation: I Divisione Medica, USL n. 56, Ospedale Maggiore di Lodi.
authors.forename: C
authors.initials: C
authors.lastname: Pandolfi
authors.forename: L
authors.initials: L
authors.lastname: Pellegrini
authors.forename: E
authors.initials: E
authors.lastname: Vitelli
authors.forename: G
authors.initials: G
authors.lastname: Sbalzarini
mesh_terms: D000328:Adult; D006111:Graves Disease / Q000150:complications* / Q000235:genetics; D015236:HLA-C Antigens / Q000235:genetics; D006801:Humans; D007008:Hypokalemia / Q000150:complications; D008297:Male; D008564:Membrane Potentials; D009123:Muscle Hypotonia; D009124:Muscle Proteins / Q000378:metabolism; D009132:Muscles / Q000378:metabolism / Q000473:pathology; D010243:Paralysis / Q000453:epidemiology / Q000209:etiology* / Q000235:genetics; D010507:Periodicity; D015995:Prevalence; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism; D013971:Thyrotoxicosis / Q000150:complications* / Q000235:genetics
chemical_list: D015236:HLA-C Antigens; C040178:HLA-C*70 antigen; D009124:Muscle Proteins; D000254:Sodium-Potassium-Exchanging ATPase
vernacular_title: Paralisi periodica tireotossica e morbo di Graves. Descrizione di un caso HLA-CW7 positivo.