Sensorimotor myeloradiculoneuropathy in thymoma.
This is the first report describing the clinical, electrophysiological, and neuropathological findings in a patient with thymoma and sensorimotor myeloradiculoneuropathy. Degeneration of the Clarke's nucleus and posterior horns were noted in addition to segmental demyelination and variable axonal loss of the anterior and posterior roots. The segmental demyelination was more severe in the anterior roots of the lower thoracic and lumbosacral regions. A possible rare association between paraneoplastic myeloradiculoneuropathy and thymoma is suggested.
Sridhar
K S
KS
Department of Oncology, University of Miami School of Medicine, Jackson Memorial Hospital, FL 33101.
Cohen
A B
AB
Bruce-Gregorios
J H
JH
Ayyar
D R
DR
D000368:Aged; D004594:Electrophysiology; D006801:Humans; D008297:Male; D010257:Paraneoplastic Syndromes / Q000473:pathology* / Q000503:physiopathology; D010523:Peripheral Nervous System Diseases / Q000209:etiology / Q000473:pathology; D013118:Spinal Cord Diseases / Q000209:etiology* / Q000473:pathology; D013126:Spinal Nerve Roots / Q000473:pathology; D013945:Thymoma / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D013953:Thymus Neoplasms / Q000150:complications* / Q000473:pathology / Q000503:physiopathology