An evaluation of antimutagenic properties of vitamin E.
The influence of vitamin E on the mutagenic activities of aflatoxin and adriamycin was studied. The results indicate that vitamin E shows antimutagenic activity towards aflatoxin B1 only when homogenized with liver tissue.
Chłopkiewicz
B
B
Drug Institute, Warsaw, Poland.
Marczewska
J
J
Koziorowska
J
J
D016604:Aflatoxin B1 / Q000037:antagonists & inhibitors / Q000633:toxicity; D000818:Animals; D016587:Antimutagenic Agents / Q000493:pharmacokinetics / Q000494:pharmacology*; D004317:Doxorubicin / Q000037:antagonists & inhibitors / Q000633:toxicity; D004353:Drug Evaluation, Preclinical; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D009152:Mutagenicity Tests; D051381:Rats; D011921:Rats, Inbred WKY; D014810:Vitamin E / Q000493:pharmacokinetics / Q000494:pharmacology*
D016587:Antimutagenic Agents; D014810:Vitamin E; D004317:Doxorubicin; D016604:Aflatoxin B1