title: [Pharmacology of neural mechanisms of the motor system].
abstract: In reviewing recent progress concerning the motor system and drug action, the following subjects will be discussed on the basis of our data: 1) the mechanisms of action of mephenesin and baclofen, 2) baclofen and gamma-aminobutyric acid B (GABAB) receptor, 3) GABA-, benzodiazepine receptors, 4) control of spinal motor system by descending noradrenergic neuron, 5) pharmacology of the muscle spindle, and 6) pharmaco-metrics of centrally acting muscle relaxants.
authors.affiliation: College of Pharmacy, Nihon University, Chiba-ken, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Fukuda
mesh_terms: D000818:Animals; D001418:Baclofen / Q000494:pharmacology*; D003864:Depression, Chemical; D004594:Electrophysiology; D008615:Mephenesin / Q000494:pharmacology*; D009046:Motor Neurons / Q000187:drug effects*; D009132:Muscles / Q000187:drug effects; D009638:Norepinephrine / Q000378:metabolism; D011963:Receptors, GABA-A / Q000145:classification / Q000378:metabolism / Q000502:physiology; D012023:Reflex, Monosynaptic / Q000187:drug effects*; D013116:Spinal Cord / Q000187:drug effects / Q000378:metabolism
chemical_list: D011963:Receptors, GABA-A; D008615:Mephenesin; D001418:Baclofen; D009638:Norepinephrine