Screening of medicinal plants from Yunnan Province in southwest China for antiviral activity.
In an ethnopharmacological screening of medicinal plants used in Yunnan province of China, ethanol extracts from 31 plant species were assayed for inhibition of murine cytomegalovirus and Sindbis virus infections. Parallel assays were carried out with and without exposure to UVA radiation to test for photo-mediation of activity. Antiviral activity was observed with 16 of the plant extracts. Eight plant extracts have been selected for further studies, with the objective of characterizing the antiviral constituents.
Yip
L
L
Department of Botany, University of British Columbia, Vancouver, Canada.
Pei
S
S
Hudson
J B
JB
Towers
G H
GH
D000998:Antiviral Agents / Q000494:pharmacology*; D002478:Cells, Cultured; D002681:China; D003587:Cytomegalovirus / Q000187:drug effects / Q000528:radiation effects; D003588:Cytopathogenic Effect, Viral / Q000187:drug effects; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D010936:Plant Extracts / Q000032:analysis / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D012845:Sindbis Virus / Q000187:drug effects / Q000528:radiation effects; D013056:Spectrophotometry, Ultraviolet; D014466:Ultraviolet Rays
D000998:Antiviral Agents; D004365:Drugs, Chinese Herbal; D010936:Plant Extracts