Rubella vaccination in pregnancy.
Ninety-two pregnancies complicated by rubella vaccination were reported to the Rubella Vaccination in Pregnancy Study between 1981 and 1990. These pregnancies resulted in 87 live births, 3 stillbirths and two spontaneous abortions. One infant had serological evidence of congenital rubella infection but was healthy and normal with no indication of rubella damage at the age of two and half years. These findings suggest that the risk of rubella-associated damage following inadvertent rubella vaccination in pregnancy or shortly before is low, and support the current advice that termination of pregnancy should not be routinely recommended in these circumstances.
Tookey
P A
PA
Epidemiology and Biostatistics Unit, Institute of Child Health, London.
Jones
G
G
Miller
B H
BH
Peckham
C S
CS
D000914:Antibodies, Viral / Q000032:analysis; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011256:Pregnancy Outcome; D012307:Risk Factors; D012410:Rubella Syndrome, Congenital / Q000209:etiology* / Q000276:immunology / Q000517:prevention & control; D012411:Rubella Vaccine / Q000008:administration & dosage / Q000009:adverse effects* / Q000276:immunology
D000914:Antibodies, Viral; D012411:Rubella Vaccine; C040901:rubella antibodies