[Specificity of neuropsychological syndromes in disorders of higher mental functions in Alzheimer's disease and senile dementia].
A comparative neuropsychological study was made of the two groups of patients: with Alzheimer's disease [AD] (n = 40) and senile dementia [SD] (n = 54). The correlation and role of different factors in the formation of syndromes of higher mental functions (HMF) impairment in AD and SD were determined. The analysis was based on the concept of the presence of operational and regulatory factors in the systemic organization of mental activity. The structure of the syndrome of HMF impairment in AD is specified by the deficiency of operational factors whereas in SD, the deficiency of regulatory factors plays the key role. The patients with AD manifest the combination of disordered operational and regulatory factors related to the work of brain blocks II and I respectively (according to Luria). In SD patients, the syndrome is marked by the predominance of the symptoms related to the deficiency of regulatory factors provided for by the structures of brain blocks III and I, with the interest of the brain areas entering block II being far less.
Korsakova
N K
NK
Dybovskaia
N R
NR
Roshchina
I F
IF
Gavrilova
S I
SI
D000368:Aged; D000544:Alzheimer Disease / Q000150:complications* / Q000175:diagnosis / Q000523:psychology; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology* / Q000523:psychology; D003704:Dementia / Q000150:complications* / Q000175:diagnosis / Q000523:psychology; D003937:Diagnosis, Differential; D006801:Humans; D008182:Luria-Nebraska Neuropsychological Battery; D008875:Middle Aged
O spetsifichnosti neĭropsikhologicheskikh sindromov narusheniia vysshikh psikhicheskikh funktsiĭ pri bolezni Al'tsgeĭmera i senil'noĭ dementsii.