Cytomegalovirus excretion after bone marrow transplantation cannot be predicted from the pre-transplant level of IgG antibodies.
The relationship of pre-bone-marrow transplant recipient and donor cytomegalovirus (CMV) antibody level to post-transplant recipient CMV excretion was investigated. CMV excretion was found to be related to pre-transplant recipient serological status, but not to level of antibody. This therefore contrasts with herpes simplex virus (HSV), for which pre-transplant antibody level in recipients predicts post-transplant HSV excretion.
Pillay
D
D
Department of Virology, Royal Free Hospital School of Medicine, London, U.K.
Webster
A
A
Lee
D
D
Prentice
H G
HG
Griffiths
P D
PD
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000378:metabolism*; D016026:Bone Marrow Transplantation / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D003587:Cytomegalovirus / Q000276:immunology*; D003586:Cytomegalovirus Infections / Q000276:immunology / Q000517:prevention & control* / Q000601:surgery; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism*; D008875:Middle Aged; D011300:Preoperative Care; D012307:Risk Factors
D000914:Antibodies, Viral; D007074:Immunoglobulin G