title: In vitro effect of high doses of morphine on Con A induced lymphokine production.
authors.affiliation: U.S. Food and Drug Administration, Center for Biologics Evaluation and Research, Bethesda, Maryland 20892.
authors.forename: J J
authors.initials: JJ
authors.lastname: Jessop
authors.forename: M S
authors.initials: MS
authors.lastname: Taplits
mesh_terms: D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D002999:Clone Cells / Q000187:drug effects / Q000378:metabolism; D005576:Colforsin / Q000494:pharmacology; D003208:Concanavalin A / Q000494:pharmacology*; D000242:Cyclic AMP / Q000096:biosynthesis; D003864:Depression, Chemical; D015232:Dinoprostone / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004745:Enkephalins / Q000494:pharmacology; D005260:Female; D008213:Lymphocyte Activation / Q000187:drug effects; D008222:Lymphokines / Q000378:metabolism*; D051379:Mice; D008810:Mice, Inbred C57BL / Q000276:immunology; D009020:Morphine / Q000494:pharmacology*; D009270:Naloxone / Q000494:pharmacology; D009271:Naltrexone / Q000494:pharmacology; D014176:Protein Biosynthesis; D011957:Receptors, Opioid / Q000187:drug effects; D013154:Spleen / Q000166:cytology; D006377:T-Lymphocytes, Helper-Inducer / Q000187:drug effects* / Q000378:metabolism; D001615:beta-Endorphin / Q000494:pharmacology
chemical_list: D004745:Enkephalins; D008222:Lymphokines; D011957:Receptors, Opioid; D003208:Concanavalin A; D005576:Colforsin; D009270:Naloxone; D009271:Naltrexone; D001615:beta-Endorphin; D009020:Morphine; D000242:Cyclic AMP; D015232:Dinoprostone