title: [Use of nitrendipine in treating patients with obliterative atherosclerosis of arteries in the lower extremities].
abstract: Twenty patients with obliterative atherosclerosis in the lower extremities arteries (Fontaine's stage II) were treated with nitrendipine (Bayotensin) given in the dose of 20 mg daily for 6 weeks. This therapy with nitrendipine produced improvement manifested by the prolongation of the distance of intermittent claudication, shortening of pain duration, increase in blood flow in the ischemic extremity, and increase in pressure index. At the same time, nitrendipine decreased ADP-produced platelet aggregation and activated fibrinolytic system. Clinical trials have shown that nitrendipine is effective in the obliterative atherosclerosis in the lower extremities.
authors.affiliation: Zakładu Farmakologii Klinicznej Katedry Farmakologii, Krakowie.
authors.forename: L
authors.initials: L
authors.lastname: Grodzińska
authors.forename: E
authors.initials: E
authors.lastname: Kostka-Trabka
authors.forename: M
authors.initials: M
authors.lastname: Basista
authors.forename: K
authors.initials: K
authors.lastname: Bieroń
authors.forename: M
authors.initials: M
authors.lastname: Sławiński
authors.forename: E
authors.initials: E
authors.lastname: Telesz
mesh_terms: D000328:Adult; D000368:Aged; D001161:Arteriosclerosis / Q000150:complications / Q000188:drug therapy*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007383:Intermittent Claudication / Q000188:drug therapy / Q000209:etiology; D007511:Ischemia / Q000188:drug therapy / Q000209:etiology; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D009568:Nitrendipine / Q000627:therapeutic use*
chemical_list: D009568:Nitrendipine
vernacular_title: Zastosowanie nitrendypiny w leczeniu chorych z miazdzyca tetnic kończyn dolnych.