title: Genetic instability occurs sooner than expected: promotion, progression and clonality during hepatocarcinogenesis in the rat.
authors.affiliation: Institute of Pathology, Case Western Reserve University, Cleveland, OH 44106.
authors.forename: O
authors.initials: O
authors.lastname: Sudilovsky
authors.forename: L I
authors.initials: LI
authors.lastname: Hinrichsen
authors.forename: T K
authors.initials: TK
authors.lastname: Hei
authors.forename: C M
authors.initials: CM
authors.lastname: Whitacre
authors.forename: J H
authors.initials: JH
authors.lastname: Wang
authors.forename: S
authors.initials: S
authors.lastname: Kasturi
authors.forename: S H
authors.initials: SH
authors.lastname: Jiang
authors.forename: R
authors.initials: R
authors.lastname: Cechner
authors.forename: S
authors.initials: S
authors.lastname: Miron
authors.forename: F
authors.initials: F
authors.lastname: Abdul-Karim
mesh_terms: D000782:Aneuploidy; D000818:Animals; D014408:Biomarkers, Tumor; D002273:Carcinogens; D006528:Carcinoma, Hepatocellular / Q000235:genetics / Q000473:pathology; D002454:Cell Differentiation; D002796:Choline Deficiency / Q000150:complications; D002869:Chromosome Aberrations; D002999:Clone Cells / Q000201:enzymology / Q000473:pathology; D003043:Cocarcinogenesis; D004273:DNA, Neoplasm / Q000235:genetics; D005260:Female; D006498:Hepatectomy; D006801:Humans; D006965:Hyperplasia; D008099:Liver / Q000187:drug effects / Q000201:enzymology / Q000473:pathology; D008113:Liver Neoplasms / Q000235:genetics / Q000473:pathology; D008114:Liver Neoplasms, Experimental / Q000139:chemically induced / Q000235:genetics* / Q000473:pathology; D008297:Male; D051379:Mice; D009154:Mutation; D009363:Neoplasm Proteins / Q000032:analysis; D011230:Precancerous Conditions / Q000235:genetics / Q000473:pathology; D051381:Rats; D011916:Rats, Inbred F344; D011919:Rats, Inbred Strains
chemical_list: D014408:Biomarkers, Tumor; D002273:Carcinogens; D004273:DNA, Neoplasm; D009363:Neoplasm Proteins