title: [The use of lanthanide immunofluorescence analysis for demonstrating the antigen of viral hepatitis A].
abstract: The study dealt with the development of an express method for detection of hepatitis A virus (HAV) antigen employing lantanides, especially europium. The new time-resolved fluoroimmunoassay (TRFIA), alongside with a significant shortening of the time for reaction, was also 8 times as sensitive as the analogous enzyme immunoassay. The TRFIA may be used effectively both for control of the antigen amplification in HAV-infected cell culture and for early diagnosis of acute forms of viral hepatitis A.
authors.forename: M A
authors.initials: MA
authors.lastname: Chernovetskiĭ
authors.forename: M V
authors.initials: MV
authors.lastname: Sokolova
authors.forename: I G
authors.initials: IG
authors.lastname: Kharitonenkov
mesh_terms: D000956:Antigens, Viral / Q000097:blood*; D005069:Evaluation Studies as Topic; D015200:Fluoroimmunoassay / Q000379:methods*; D006507:Hepatovirus / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques; D008674:Metals, Rare Earth
chemical_list: D000956:Antigens, Viral; D008674:Metals, Rare Earth
vernacular_title: Primenenie lantanidnogo immunofliuorestsentnogo analiza dlia indikatsii antigena virusnogo gepatita A.