title: Plasma cyclic AMP increases in hamsters following exposure to a graded footshock stressor.
abstract: To assess the utility of plasma cyclic AMP (cAMP) as a sensitive physiological index of an animal's arousal level, we exposed male hamsters to various intensities (0.0-2.0 mA) of a footshock stressor. The plasma cAMP response was directly related to stimulus intensity. Ratings of behavioral arousal were positively correlated with plasma cAMP values. We conclude that plasma cAMP may be a useful index of arousal.
authors.affiliation: Department of Medical Neurosciences, Walter Reed Army Institute of Research, Washington, D.C.
authors.forename: K L
authors.initials: KL
authors.lastname: Huhman
authors.forename: M A
authors.initials: MA
authors.lastname: Hebert
authors.forename: J L
authors.initials: JL
authors.lastname: Meyerhoff
authors.forename: B N
authors.initials: BN
authors.lastname: Bunnell
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000502:physiology; D006224:Cricetinae; D000242:Cyclic AMP / Q000097:blood*; D004558:Electric Stimulation; D008297:Male; D008647:Mesocricetus / Q000097:blood*; D011863:Radioimmunoassay; D013312:Stress, Physiological
chemical_list: D000242:Cyclic AMP