Lithium: serum levels, renal effects, and dosing strategies.
Lithium prescribing practices have changed over the course of its forty years of use in psychiatric patients. Currently there are controversies as to clinically effective serum levels, dosing strategies, and effects of lithium on renal functioning. These issues are discussed, and recommendations are offered for effective management of the patient taking lithium.
Gitlin
M J
MJ
University of California, Neuropsychiatric Institute and Hospital, Los Angeles 90024-1759.
D001714:Bipolar Disorder / Q000097:blood / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D006801:Humans; D007668:Kidney / Q000187:drug effects*; D007677:Kidney Function Tests; D008094:Lithium / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics
D008094:Lithium