title: The surgical management of familial adenomatous polyposis in Northern Ireland.
abstract: Sixty-eight patients from 18 families have been identified as having familial adenomatous polyposis during the past 30 years in Northern Ireland (population 1.5 million). Six of the 18 probands (33%) had developed colonic carcinoma when first seen at mean age 34 years. Ten of the 44 patients identified by surgical screening (21%) at a significantly lower mean age of 23 years had colonic carcinoma. Surgical management has generally been by subtotal colectomy with ileorectal anastomosis, or by panproctocolectomy and ileostomy.
authors.affiliation: Department of Surgery, Queen's University of Belfast, Belfast City Hospital.
authors.forename: W J
authors.initials: WJ
authors.lastname: Campbell
authors.forename: S T
authors.initials: ST
authors.lastname: Irwin
authors.forename: T G
authors.initials: TG
authors.lastname: Parks
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000150:complications / Q000453:epidemiology / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D002648:Child; D003110:Colonic Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000601:surgery*; D006801:Humans; D015994:Incidence; D008403:Mass Screening; D008875:Middle Aged; D009660:Northern Ireland / Q000453:epidemiology; D012086:Reoperation / Q000706:statistics & numerical data