[The effect of experimental fever in female rabbits on the temperature homeostasis of their fetuses].
I.v. administration of interleukin-1 induced an increment of body temperature in female rabbits. The temperature gradient between female rabbit and its underdeveloped foetus decreased more obviously than between normally developed foetus and female rabbit. This different reaction is associated with the hemodynamics specifics in placenta and foetuses. An increase of the gradient as compared with initial values during the restoration of normal body temperature suggests a more considerable disturbance of the uterus-placenta circulation and a worsening of the foetus state during this phase of the fever.
Nazarova
L A
LA
D000818:Animals; D001831:Body Temperature / Q000187:drug effects / Q000502:physiology; D001833:Body Temperature Regulation / Q000187:drug effects / Q000502:physiology*; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology / Q000503:physiopathology; D005333:Fetus / Q000187:drug effects / Q000502:physiology*; D005334:Fever / Q000139:chemically induced / Q000503:physiopathology*; D006339:Heart Rate / Q000187:drug effects / Q000502:physiology; D006340:Heart Rate, Fetal / Q000187:drug effects / Q000502:physiology; D006706:Homeostasis / Q000187:drug effects / Q000502:physiology*; D007375:Interleukin-1 / Q000494:pharmacology; D011247:Pregnancy; D011817:Rabbits
D007375:Interleukin-1
Vliianie éksperimental'noĭ likhoradki u samok krolika na temperaturnyĭ gomeostaz ikh plodov.