Spinal growth after irradiation for Wilm's tumour.
Between 1960 and 1983, 82 children were treated for Wilm's tumour at our hospital. The secondary effects and changes in the skeleton have been assessed. Radiotherapy was found to cause growth disturbances and osteochondrosis of variable degree, but not osteonecrosis. Since irradiation produces late damage, it should be applied symmetrically to the spine and the dose limited as far as is possible. A long follow up is necessary since skeletal damage can only be assessed after the end of growth.
Scheibel-Jost
P
P
Department of Orthopaedics, University Hospital, Heidelberg, Federal Republic of Germany.
Pfeil
J
J
Niethard
F U
FU
Fromm
B
B
Willich
E
E
Kuttig
H
H
D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000532:radiotherapy*; D007738:Kyphosis / Q000209:etiology; D008297:Male; D010007:Osteochondritis / Q000209:etiology; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy / Q000009:adverse effects*; D012600:Scoliosis / Q000209:etiology; D013131:Spine / Q000254:growth & development* / Q000528:radiation effects; D009396:Wilms Tumor / Q000532:radiotherapy*