Establishment of clonal cell lines, with or without cartilage phenotypes, from a hamster mesenchymal chondrosarcoma.
A hamster mesenchymal chondrosarcoma was found in the soft tissues of the cheek pouch and has been successfully transplanted. The tumor was composed principally of two cell types: poorly differentiated mesenchymal cells and focal areas of cells in islands showing cartilaginous differentiation. The clonal cell lines, MCS-1 and MCS-8 which closely correspond to the respective cell types in the original tumor were also established. MCS-1 cells formed an undifferentiated sarcoma in the subcutaneous layer of nude mice and MCS-8 cells formed a chondrosarcoma of a common type.
Fujisawa
N
N
1st Department of Pathology, Niigata University School of Medicine, Japan.
Sato
N L
NL
Motoyama
T
T
D000818:Animals; D002356:Cartilage / Q000473:pathology; D002813:Chondrosarcoma / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D002999:Clone Cells / Q000378:metabolism / Q000473:pathology; D003094:Collagen / Q000378:metabolism; D006224:Cricetinae; D003412:Cricetulus; D007621:Karyotyping; D010641:Phenotype; D012983:Soft Tissue Neoplasms / Q000235:genetics / Q000378:metabolism / Q000473:pathology*; D014407:Tumor Cells, Cultured / Q000378:metabolism / Q000473:pathology
D003094:Collagen