[Dysontogenesis of the brain of the progeny born to mothers drinking alcohol during pregnancy].
A study was made of the development of the brain from 44 embryos (5-12 weeks) and 1 fetus (14 weeks) obtained from mothers who used alcohol during pregnancy. 16 cases made up the control group. In 34 cases out of 45 (75.5%), deviations in the development of the brain were established and distributed into the three degrees of gravity: mild, moderate and severe. 11 variants of brain pathology are described. Deviations in the formation of brain walls and disorders of the development of the cortical lamina occurred most frequently (70.6 and 57.9%, respectively). In alcoholic mothers, brain pathology in their progeny was revealed in 100% of cases. Provided they used alcohol systematically and frequently, brain pathology was identified in 83.3% of cases, in systematic rare use of alcohol in 77.3%, and in episodic use of alcohol in 28.5% of cases.
Kovetskiĭ
N S
NS
Konovalov
G V
GV
Orlovskaia
D D
DD
Semke
V Ia
VIa
Solonskiĭ
A V
AV
D000328:Adult; D000437:Alcoholism / Q000473:pathology*; D001284:Atrophy / Q000209:etiology / Q000473:pathology; D001921:Brain / Q000002:abnormalities / Q000196:embryology / Q000473:pathology*; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000150:complications / Q000473:pathology*; D006801:Humans; D006965:Hyperplasia / Q000209:etiology / Q000473:pathology; D007231:Infant, Newborn; D008431:Maternal-Fetal Exchange; D008831:Microcephaly / Q000209:etiology* / Q000473:pathology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000473:pathology*
Dizontogenez golovnogo mozga potomstva matereĭ, upotrebliavshikh alkogol' v period beremennosti.