title: Interaction of heterologous fibrinogens with human platelet receptors.
abstract: The interaction of ADP-stimulated human platelets with human 125I-fibrinogen as well as with pig and bovine fibrinogens was analysed. It was found that the fibrinogens studied were bound to the same platelet receptors but the affinity of animal preparations was about half the value observed for human fibrinogen (in a homologous system).
authors.affiliation: Department of Biochemistry, University of Lódź, Poland.
authors.forename: P
authors.initials: P
authors.lastname: Nowak
authors.forename: T
authors.initials: T
authors.lastname: Krajewski
authors.forename: T
authors.initials: T
authors.lastname: Pietrucha
authors.forename: C
authors.initials: C
authors.lastname: Cierniewski
mesh_terms: D000244:Adenosine Diphosphate / Q000494:pharmacology; D000818:Animals; D001665:Binding Sites; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism*; D002417:Cattle; D005340:Fibrinogen / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D011956:Receptors, Cell Surface / Q000378:metabolism*; D018000:Receptors, Peptide
chemical_list: D011956:Receptors, Cell Surface; D018000:Receptors, Peptide; C048650:fibrin-fibrinogen degradation products receptor; D000244:Adenosine Diphosphate; D005340:Fibrinogen