Fibrinolytic activity in human malignant tumors.
We have studied fibrinolytic activity of 12 cases of infiltrating duct carcinoma of breast (7 metastatic and 5 non-metastatic) and ten cases of adenocarcinoma of gastrointestinal tract (5 each of metastatic and nonmetastatic), and compared with some of their normal tissue counterparts. Both metastatic and non-metastatic tumors of breast and gastrointestinal tract had significantly higher levels of fibrinolytic activity as compared to normal tissues. Though mean fibrinolytic activity (expressed as ug/ml of urokinase activity) of metastatic tumors of breast and gut had higher values as compared to non-metastatic counterparts, however it did not reach statistical significance.
Sarode
R
R
Department of Hematology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Marwaha
N
N
Gupta
N M
NM
D000230:Adenocarcinoma / Q000503:physiopathology*; D001943:Breast Neoplasms / Q000503:physiopathology*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000503:physiopathology*; D005260:Female; D005342:Fibrinolysis; D005770:Gastrointestinal Neoplasms / Q000503:physiopathology*; D006801:Humans