title: Protein-induced hyperthermia for liver cancer treatment.
abstract: It is suggested that the thermic effect of protein be exploited as a means of hyperthermia therapy in the treatment of liver cancer. Oral ingestion of high amounts of protein or intravenous amino acid therapy could generate heat directly within the hepatocytes primarily through urea synthesis. This approach could enhance the effects of conventional hyperthermia or radiation therapy.
authors.affiliation: Hematology-Oncology Division, University of Cincinnati Medical School, OH 45267-0562.
authors.forename: E J
authors.initials: EJ
authors.lastname: Norman
mesh_terms: D000596:Amino Acids / Q000008:administration & dosage; D006528:Carcinoma, Hepatocellular / Q000178:diet therapy / Q000628:therapy; D004044:Dietary Proteins / Q000008:administration & dosage*; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D008113:Liver Neoplasms / Q000178:diet therapy / Q000628:therapy*; D008954:Models, Biological
chemical_list: D000596:Amino Acids; D004044:Dietary Proteins