[3H]1,3-Di(2-tolyl)guanidine labels two high affinity binding sites in guinea pig brain: evidence for allosteric regulation by calcium channel blockers and sigma ligands.
Rothman
R B
RB
Unit on Receptor Studies, LCS, NIMH, Bethesda, MD 20892.
Mahboubi
A
A
Reid
A A
AA
Kim
C H
CH
deCosta
B R
BR
Jacobson
A E
AE
Rice
K C
KC
D000818:Animals; D001665:Binding Sites / Q000187:drug effects*; D001923:Brain Chemistry / Q000187:drug effects*; D002121:Calcium Channel Blockers / Q000494:pharmacology*; D006146:Guanidines / Q000493:pharmacokinetics; D006168:Guinea Pigs; D066298:In Vitro Techniques; D008024:Ligands; D008566:Membranes / Q000187:drug effects / Q000378:metabolism; D011957:Receptors, Opioid / Q000187:drug effects*; D017480:Receptors, sigma
D002121:Calcium Channel Blockers; D006146:Guanidines; D008024:Ligands; D011957:Receptors, Opioid; D017480:Receptors, sigma; C050232:1,3-ditolylguanidine