Intracellular concentrations and ouabain-induced fluxes of sodium and potassium in erythrocytes of normotensive Zimbabweans.
Intracellular Na and K concentrations as well as ouabain-induced transmembrane net Na and K fluxes were measures in erythrocytes (TBC) of 22 adult Black male Zimbabweans. The intracellular Na concentration was 9.1 +/- 0.44 mmol/l RBC, the K concentration 90.7 +/- 1.33 mmol/l RBC and the ouabain (0.1 mM)-induced Na influx 1.55 +/- 0.132 mmol/hr.1 RBC. The intracellular Na concentration is higher than most values reported from studies of Whites, but the intracellular K concentration and the ouabain-induced Na influx compare with literature values. No significant correlation was found between intracellular Na concentration and blood pressure.
Mubagwa
K
K
Department of Pharmacology, University of Connecticut Farmington 06032.
Wagaine-Twabwe
D
D
Matimba
N
N
D000328:Adult; D044383:Black People; D001794:Blood Pressure; D015992:Body Mass Index; D004912:Erythrocytes / Q000737:chemistry* / Q000187:drug effects; D006801:Humans; D007424:Intracellular Fluid / Q000737:chemistry* / Q000187:drug effects; D008297:Male; D010042:Ouabain / Q000494:pharmacology*; D011188:Potassium / Q000737:chemistry*; D012016:Reference Values; D012964:Sodium / Q000737:chemistry*; D000254:Sodium-Potassium-Exchanging ATPase / Q000187:drug effects; D015030:Zimbabwe
D010042:Ouabain; D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase; D011188:Potassium