Treatment of postoperative Aspergillus fumigatus spondylodiscitis with itraconazole.
A 46-year-old man presented with Aspergillus fumigatus spondylodiscitis after lumbar surgery. He was successfully treated with the new antifungal drug itraconazole in combination with surgical débridement of the disc space. The patient has remained on itraconazole for more than a year and tolerated the drug well.
Peters-Christodoulou
M N
MN
Department of Infectious Diseases, University Hospital, Leiden, The Netherlands.
de Beer
F C
FC
Bots
G T
GT
Ottenhoff
T M
TM
Thompson
J
J
van 't Wout
J W
JW
D000935:Antifungal Agents / Q000627:therapeutic use*; D001228:Aspergillosis / Q000188:drug therapy*; D001232:Aspergillus fumigatus; D003131:Combined Modality Therapy; D003646:Debridement; D015299:Discitis / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D017964:Itraconazole; D007654:Ketoconazole / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D013530:Surgical Wound Infection / Q000188:drug therapy* / Q000601:surgery
D000935:Antifungal Agents; D017964:Itraconazole; D007654:Ketoconazole