title: Neurophysiological aspects of smoking behaviour: a neuroelectric perspective.
abstract: Many of the current neurobiological hypotheses of tobacco smoking concern relationships between nicotine-induced neurotransmitter alterations--events at the level of the individual neuron--and mental behavioural states. Since non-invasive physiological variables may reflect neural activity more directly than overt indices, neuroelectric studies are suggested to be particularly helpful in understanding the intermediate steps between the neuronal effects of smoke/nicotine and behavioural change. The intent of this paper is to offer direction and suggestion regarding electroencephalographic (EEG) and event-related brain potential (ERP) research into smoke/nicotine effects on mood and performance. Suggested directions revolve around multi-component measurement strategies and the employment of study designs and test paradigms which may offer a more dynamic and detailed neurobiological view of smoke/nicotine effects on these processes.
authors.affiliation: Clinical Neurophysiological Services, University of Ottawa, Royal Ottawa Hospital, Ontario, Canada.
authors.forename: V J
authors.initials: VJ
authors.lastname: Knott
mesh_terms: D000818:Animals; D001143:Arousal / Q000187:drug effects* / Q000502:physiology; D001288:Attention / Q000187:drug effects / Q000502:physiology; D001921:Brain / Q000187:drug effects* / Q000503:physiopathology; D004569:Electroencephalography / Q000187:drug effects* / Q000295:instrumentation; D009538:Nicotine / Q000494:pharmacology*; D051381:Rats; D011930:Reaction Time / Q000187:drug effects / Q000502:physiology; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation; D012907:Smoking / Q000503:physiopathology*; D009435:Synaptic Transmission / Q000187:drug effects* / Q000502:physiology
chemical_list: D009538:Nicotine