title: Treatment of advanced condylomata acuminata with semi-purified and purified human leukocyte interferon.
abstract: Twelve patients with advanced condylomata acuminata were treated by systemic human leukocyte interferon (IFN) therapy. Semi-purified and purified preparations were both able to affect condylomatous growth. Treatment of the patients at various periods of their disease resulted in one complete remission, 6 partial remissions, 4 minimal responses while one case showed progressive disease. Side-effects were unexpectedly common in these advanced patients and 4 of them had to stop IFN treatment.
authors.affiliation: Department of Oncology, Karolinska Hospital, Stockholm, Sweden.
authors.forename: N
authors.initials: N
authors.lastname: Einhorn
authors.forename: P
authors.initials: P
authors.lastname: Ling
authors.forename: D
authors.initials: D
authors.lastname: Secher
authors.forename: H
authors.initials: H
authors.lastname: Strander
mesh_terms: D000328:Adult; D003218:Condylomata Acuminata / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007370:Interferon Type I / Q000009:adverse effects / Q000302:isolation & purification / Q000627:therapeutic use*; D008875:Middle Aged; D027383:Papillomaviridae; D014846:Vulvar Neoplasms / Q000188:drug therapy*
chemical_list: D007370:Interferon Type I