[Alexander's disease].
Alexander disease, or hypoproconvertinemia is a rare autosomic recessive coagulation disorder. The features include familial and/or personal history of bleeding, with an abnormal prothrombin period and a normal activated partial thromboplastin period. Coagulation and genetic studies allow subclassification with prognosis incidence for this disease. The authors report on a case of one family with Alexander disease.
Elian
J C
JC
Service de chimiothérapie massive et greffe de moelle, hôpital nord, Saint Prietz en Jarez, France.
Frappaz
D
D
Reynaud
J
J
Perrot
S
S
Freycon
F
F
D002648:Child; D005168:Factor VII Deficiency / Q000150:complications / Q000235:genetics* / Q000276:immunology; D014644:Genetic Variation; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D008297:Male
La maladie d'Alexander.