[A method for determining the classification of a protein in a given family at a low level of similarity].
Basing on the analysis of the primary structure of proteins from a family of signal receptor proteins, the existence of short extremely conservative family-specific chains was postulated. These chains may serve as a marker in determination of the relationship of a protein to the given family. On the basis of the performed analysis, it is suggested that mass-oncogene belongs to the family of signal receptors, whereas pheromonal receptor of the yeasts STE-2--presumably does not.
Klebanov
S E
SE
Bochina
Iu M
IuM
Berman
A L
AL
D000595:Amino Acid Sequence; D000818:Animals; D006224:Cricetinae; D006801:Humans; D009363:Neoplasm Proteins / Q000145:classification; D021382:Protein Sorting Signals / Q000145:classification; D011505:Protein-Tyrosine Kinases / Q000145:classification; D011506:Proteins / Q000145:classification*; D000090063:Proto-Oncogene Mas; D011518:Proto-Oncogene Proteins / Q000145:classification; D011943:Receptors, Adrenergic, beta / Q000145:classification; D043562:Receptors, G-Protein-Coupled; D012243:Rhodopsin / Q000145:classification
D009363:Neoplasm Proteins; D021382:Protein Sorting Signals; D011506:Proteins; D000090063:Proto-Oncogene Mas; D011518:Proto-Oncogene Proteins; D011943:Receptors, Adrenergic, beta; D043562:Receptors, G-Protein-Coupled; D012243:Rhodopsin; D011505:Protein-Tyrosine Kinases
Metod opredeleniia prinadlezhnosti belka k dannomu semeĭstvu pri malom urovne skhodstva.