title: Cervical neoplasia and human papilloma virus infection in prostitutes.
abstract: OBJECTIVE
  To evaluate the prevalence and incidence of PAP smears indicating cervical dysplasia as well as human papillomavirus (HPV) infection in prostitutes.
  
  
  METHODS
  Prevalence and incidence study of cervical dysplasia and HPV infection in prostitutes. For detection and typing of HPV-DNA In Situ Hybridisation (ISH) was performed in tissue samples with CIN gained by colposcopically directed punch biopsies.
  
  
  METHODS
  Second Department of Obstetrics and Gynecology, University of Vienna Medical School and STD Clinic of the Public Health Office, Vienna.
  
  
  METHODS
  Registered prostitutes attending the STD Clinic of the Public Health Office and a control group.
  
  
  RESULTS
  978 prostitutes and 5493 women with unknown cytological anamnesis were compared. Frequency of positive PAP smears was significantly higher in prostitutes (6.13% versus 1.43%). To determine the pick-up rate of cervical dysplasia during one year after negative cytology we compared 722 prostitutes and 3162 controls. Prostitutes showed a significant higher dysplasia pick-up rate (3.05% to 1.07%) compared with controls. HPV detection rate in prostitutes was similar to that in the control group. The distribution of HPV types revealed a higher frequency of "high risk" HPV 16/18 and 31/33 in prostitutes.
  
  
  CONCLUSIONS
  The results demonstrate a higher incidence and prevalence of cervical dysplasia in prostitutes and therefore suggest regular cervical PAP smear screening in registered prostitutes twice a year.
authors.affiliation: Second Department of Obstetrics and Gynecology, University of Vienna, Austria.
authors.forename: G
authors.initials: G
authors.lastname: Gitsch
authors.forename: C
authors.initials: C
authors.lastname: Kainz
authors.forename: A
authors.initials: A
authors.lastname: Reinthaller
authors.forename: W
authors.initials: W
authors.lastname: Kopp
authors.forename: G
authors.initials: G
authors.lastname: Tatra
authors.forename: G
authors.initials: G
authors.lastname: Breitenecker
mesh_terms: D002584:Cervix Uteri / Q000473:pathology; D005260:Female; D006801:Humans; D015994:Incidence; D065006:Papanicolaou Test; D027383:Papillomaviridae; D015995:Prevalence; D011477:Sex Work; D014412:Tumor Virus Infections / Q000453:epidemiology*; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology*; D014626:Vaginal Smears