Primary gastric T-cell lymphoma with manifold histologic appearances.
A rare case of malignant T-cell lymphoma with manifold histologic appearances was described. The lymphoma occurred in the stomach of a 50-year-old Japanese male. Grossly, the lymphoma exhibited a deeply ulcerated mass. Histologically, in addition to diffuse infiltrate of large lymphoid cells with deeply indented nuclei, there were many epithelioid cell granulomas, remarkable tissue eosinophilia and stromal fibrosis, mimicking inflammatory disease. Immunohistochemical studies and a gene analysis demonstrated the T-cell phenotype.
Kurihara
K
K
Department of Pathology, Uwajima City Hospital, Japan.
Mizuseki
K
K
Ichikawa
M
M
Kohno
H
H
Okanoue
T
T
D014408:Biomarkers, Tumor / Q000032:analysis; D015139:Blotting, Southern; D002467:Cell Nucleus / Q000648:ultrastructure; D004273:DNA, Neoplasm / Q000235:genetics; D004802:Eosinophilia / Q000473:pathology; D005355:Fibrosis / Q000473:pathology; D015333:Gene Rearrangement, beta-Chain T-Cell Antigen Receptor / Q000235:genetics; D006801:Humans; D007150:Immunohistochemistry; D016399:Lymphoma, T-Cell / Q000737:chemistry / Q000235:genetics / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009113:Muramidase / Q000032:analysis; D010641:Phenotype; D009418:S100 Proteins / Q000032:analysis; D013270:Stomach / Q000473:pathology / Q000648:ultrastructure; D013274:Stomach Neoplasms / Q000737:chemistry / Q000235:genetics / Q000473:pathology*
D014408:Biomarkers, Tumor; D004273:DNA, Neoplasm; D009418:S100 Proteins; D009113:Muramidase