title: Treatment of disseminated onychomycosis due to Trichophyton rubrum with itraconazole under control of plasma levels.
abstract: Successful treatment of a disseminated Trichophyton rubrum infection of the nails is reported. Under therapy with 50 mg/100 mg itraconazole daily total remission was achieved after 5 months (finger nails) and 6 months (toe nails) respectively. Plasma levels of itraconazole were determined twice a month to control the regularity of the treatment using HPLC.
authors.affiliation: Department of Dermatology, University of Erlangen, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Schrenker
authors.forename: H U
authors.initials: HU
authors.lastname: Koch
mesh_terms: D000935:Antifungal Agents / Q000097:blood / Q000627:therapeutic use*; D016903:Drug Monitoring; D005260:Female; D005533:Foot Dermatoses / Q000188:drug therapy; D006229:Hand Dermatoses / Q000188:drug therapy; D006801:Humans; D017964:Itraconazole; D007654:Ketoconazole / Q000031:analogs & derivatives* / Q000097:blood / Q000627:therapeutic use; D008875:Middle Aged; D014009:Onychomycosis / Q000188:drug therapy*
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D007654:Ketoconazole