[Antibodies to the structural elements of the neuron in patients with amyotrophic lateral sclerosis and in their healthy relatives].
The results of determining antibodies to the structural elements of neuron in the serum and CSF of 100 patients with lateral amyotrophic sclerosis (LAS), in the serum of their relatives (n-67), and in biological fluids of 50 patients suffering from other neurologic diseases allowed the following conclusions to be made. The predominance of antibody demonstration in the CSF of LAS patients over that in the serum may attest to the immune response on the part of the CNS. The presence of antibodies in the relatives (not-blood ones for the most part) of LAS patients suggests an infectious nature of the disease.
Zavalishin
I A
IA
Roĭkhel'
V M
VM
Fokina
G I
GI
Kozlovskiĭ
A D
AD
Pogodina
V V
VV
D000328:Adult; D000368:Aged; D000690:Amyotrophic Lateral Sclerosis / Q000235:genetics / Q000276:immunology*; D000906:Antibodies / Q000032:analysis*; D002555:Cerebrospinal Fluid / Q000276:immunology; D007562:Creutzfeldt-Jakob Syndrome / Q000276:immunology; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007382:Intermediate Filaments / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000276:immunology; D009474:Neurons / Q000276:immunology*
D000906:Antibodies
Antitela k strukturnym élementam neĭrona u bol'nykh bokovym amiotroficheskim sklerozom i ikh zdorovykh rodstvennikov.