title: Glomus tympanicum tumors: a clinical perspective.
abstract: Since Guild first discovered glomus bodies in the middle ear, the diagnostic evaluation and therapy of glomus tympanicum tumors have remained challenging. This study describes 73 cases diagnosed as glomus tympanicum tumors over the past 30 years. During this period, imaging techniques have markedly improved, and surgical approaches have evolved and been refined. These 73 cases were reviewed from a clinical perspective involving presentation, diagnostic evaluation, and therapeutic management. Pulsatile tinnitus was the primary symptom in over half the patients, followed by hearing loss in one third. The physical exam rarely revealed a circumferential view of the lesion, emphasizing the necessity of further diagnostic evaluation. High-resolution computerized tomography (CT) is currently the radiographic study of choice. A transmastoid surgical approach with extended facial recess was most commonly employed. Extension to the jugular bulb or internal carotid was rare, and no intraoperative complications of catecholamine secretion were noted. Postoperative complications were few, and the overall residual/recurrence rate was less than 5%. Additional clinical insights may assist in the management of these rare but fascinating tumors.
authors.affiliation: House Ear Clinic, University of Southern California School of Medicine, Los Angeles.
authors.forename: M J
authors.initials: MJ
authors.lastname: O'Leary
authors.forename: C
authors.initials: C
authors.lastname: Shelton
authors.forename: N A
authors.initials: NA
authors.lastname: Giddings
authors.forename: J
authors.initials: J
authors.lastname: Kwartler
authors.forename: D E
authors.initials: DE
authors.lastname: Brackmann
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002339:Carotid Arteries; D004427:Ear Diseases / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D004428:Ear Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005260:Female; D005918:Glomus Tumor / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006314:Hearing Loss, Conductive / Q000175:diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D014012:Tinnitus / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D014432:Tympanic Membrane