title: Carcinoembryonic antigen and alpha-lactalbumin in phylloid tumor tissues.
abstract: The concentration of carcinoembryonic antigen and alpha-lactalbumin in tumor tissue cytosol were analyzed in a group of 19 tumors of cystosarcoma phyllodes type. Both antigens were also localized in the tissue of identical tumors by means of immunohistochemical procedure. The cytosol levels of both proteins were found to be higher in the histologically defined malignant type of phylloid tumors. This group was also characterized by the simultaneous occurrence of both antigens. We did not manage to prove any relationship between the presence of alpha-lactalbumin and the steroid hormone receptor positivity in tumor tissue.
authors.affiliation: Masaryk Memorial Cancer Institute, Brno, Czechoslovakia.
authors.forename: M
authors.initials: M
authors.lastname: Simícková
authors.forename: B A
authors.initials: BA
authors.lastname: Lang
authors.forename: P
authors.initials: P
authors.lastname: Stratil
authors.forename: I
authors.initials: I
authors.lastname: Vermousek
authors.forename: A
authors.initials: A
authors.lastname: Rejthar
authors.forename: M
authors.initials: M
authors.lastname: Cernoch
authors.forename: Z
authors.initials: Z
authors.lastname: Pacovský
mesh_terms: D001943:Breast Neoplasms / Q000737:chemistry* / Q000473:pathology; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000737:chemistry; D003600:Cytosol / Q000737:chemistry; D005348:Fibrocystic Breast Disease / Q000737:chemistry; D006801:Humans; D007124:Immunoenzyme Techniques; D007768:Lactalbumin / Q000032:analysis*; D009363:Neoplasm Proteins / Q000032:analysis*; D003557:Phyllodes Tumor / Q000737:chemistry* / Q000473:pathology
chemical_list: D002272:Carcinoembryonic Antigen; D009363:Neoplasm Proteins; D007768:Lactalbumin