[Study of atherogenic, coagulant and cardio-cerebral risk factors in the pathogenesis of minor strokes in arterial hypertension].
The paper is concerned with the results of studying risk factors correlations in patients who suffered minor brain stroke (MBS) associated with different forms of arterial hypertension (AH). As regards their importance in the pathogenesis of MBS, risk factors may be distributed into the two categories: atherogenic, coagulant and vascular alterations and ++cardio-cerebral ones characterizing the status of heart pump function. The atherogenic and coagulant risk factors (perivascular and intravascular lesions, agglutination of the capillaries by formed elements of the blood, aggregation of red blood cells, a high level of TH and beta-lipoproteins, fibrinogen and prothrombin) are significantly marked more widely and intensely among persons suffering from stable AH, with a history of MBS. Risk factors characterizing a decrease of heart pump function (myocardial contractility, ejection fractions) were demonstrable without significant differences among persons who suffered MBS associated with stable and labile AH. As to further studies, of the main interest is the pathogenesis of MBS in persons suffering from mild, episodic AH, since the data obtained may cast doubt on the thrombocoagulant mechanism thereof.
Bardin
A I
AI
D001777:Blood Coagulation / Q000502:physiology*; D002561:Cerebrovascular Disorders / Q000209:etiology*; D005260:Female; D006333:Heart Failure / Q000150:complications*; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications*; D006973:Hypertension / Q000150:complications / Q000503:physiopathology*; D008055:Lipids / Q000097:blood*; D008297:Male; D009200:Myocardial Contraction / Q000502:physiology*; D012307:Risk Factors; D013923:Thromboembolism / Q000150:complications*
D008055:Lipids
K izucheniiu aterogennykh, koaguliantnykh i kardiotserebral'nykh faktorov riska v patogeneze malykh insul'tov pri arterial'noĭ gipertonii.