title: Adrenocorticotropic hormone insensitivity associated with autonomic nervous system disorders.
abstract: Five children with adrenocorticotropic hormone (ACTH) insensitivity associated with autonomic nervous system disorders are described. At the time of diagnosis, four of them had osteoporosis. The fifth patient died and skeletal roentgenograms were not done. Osteoporosis was subsequently discovered in one of our previously reported patients with ACTH insensitivity. We assume that osteoporosis is, at least partly, the result of decreased adrenal androgen production. Human leucocyte antigen typing failed to establish any linkage.
authors.affiliation: Department of Paediatrics, University Hospital Rebro, Zagreb, Yugoslavia.
authors.forename: M
authors.initials: M
authors.lastname: Dumić
authors.forename: A
authors.initials: A
authors.lastname: Radica
authors.forename: Z
authors.initials: Z
authors.lastname: Sabol
authors.forename: V
authors.initials: V
authors.lastname: Plavsić
authors.forename: L
authors.initials: L
authors.lastname: Brkljacić
authors.forename: V
authors.initials: V
authors.lastname: Sarnavka
authors.forename: J
authors.initials: J
authors.lastname: Vuković
mesh_terms: D000304:Adrenal Cortex Function Tests; D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D001342:Autonomic Nervous System Diseases / Q000235:genetics / Q000378:metabolism*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male
chemical_list: D000324:Adrenocorticotropic Hormone