An unusual cause of recurrent chorea.
Recurrent chorea is described in a 61-year-old woman who had had chorea gravidarum when she was younger. The recurrent chorea appeared to be induced by a topical vaginal cream that contained conjugated estrogen. This case is consistent with the existence of a recurrent syndrome of hormone-induced chorea. The effect of estrogen on the basal ganglia is complex and not fully understood.
Caviness
J N
JN
Lee Silverman Center for Parkinson's Disease and Movement Disorders, Mayo Clinic Scottsdale, AZ 85259.
Muenter
M D
MD
D000282:Administration, Intravaginal; D002819:Chorea / Q000139:chemically induced* / Q000503:physiopathology; D004305:Dose-Response Relationship, Drug; D015914:Estrogen Replacement Therapy / Q000009:adverse effects*; D004967:Estrogens / Q000502:physiology; D004966:Estrogens, Conjugated (USP) / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012008:Recurrence
D004967:Estrogens; D004966:Estrogens, Conjugated (USP)