[Study of luminol-dependent chemiluminescence of peripheral blood in acute pneumonia].
Active oxygen forms (AOF) were measured in whole peripheral blood of 40 acute pneumonia patients using luminol-dependent spontaneous chemiluminescence (LDSC) and luminol-dependent zymosan-stimulated chemiluminescence (LDZSC) in the time course of the disease. Within week 1 of the disease both LDSC and LDZSC were increased in the majority of patients whereas low levels of AOF production served a predictor of poor prognosis in relation to acute pneumonia complications. If high intensity of LDSC and LDZSC persisted for 2 weeks pneumonia was likely to resolve completely though complications were possible. Protracted disease was associated with 3-week high AOF production. The data give evidence for possible application of LDSC and LDZSC of whole peripheral blood to predict complications and incomplete resolution of acute pneumonia.
Baltiĭskaia
N V
NV
Korkina
L G
LG
Selivanov
I I
II
Solov'eva
I A
IA
Chupeeva
N G
NG
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D005260:Female; D005609:Free Radicals; D006801:Humans; D006861:Hydrogen Peroxide / Q000097:blood*; D006878:Hydroxides / Q000097:blood*; D008163:Luminescent Measurements; D008165:Luminol; D008297:Male; D011014:Pneumonia / Q000097:blood* / Q000175:diagnosis; D013481:Superoxides / Q000097:blood*
D005609:Free Radicals; D006878:Hydroxides; D013481:Superoxides; D008165:Luminol; C031356:hydroxide ion; D006861:Hydrogen Peroxide
Issledovanie liuminolzavisimoĭ khemiliuminestsentsii periferi- cheskoĭ krovi pri ostroĭ pnevmonii.