title: [Rupture of hepatocellular carcinoma with multiple pulmonary metastasis successfully treated by transcatheter arterial embolization (TAE) of tumor: a case report].
abstract: A 66-year-old woman was hospitalized in a state of shock with rupture of hepatocellular carcinoma and multiple pulmonary metastasis. Her bleeding was successfully controlled by emergency transcatheter arterial embolization with Lipiodol (Lp-TAE). Treatments with UFT, OK-432 and two additional Lp-TAE caused the disappearance of pulmonary metastasis with AFP levels decreased and natural killer cell activity increased. The patient died one and a half years after the emergency Lp-TAE. The disappearance of pulmonary metastatic lesions seemed to be caused by improvement of the patient's immunity, which related to the regression of primary tumor after Lp-TAE. It was suggested that Lp-TAE is worth undertaking even in rupture of hepatocellular carcinoma with remote metastatic lesions.
authors.affiliation: Dept. of Internal Medicine, Komonji Hospital, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Sawada
authors.forename: S
authors.initials: S
authors.lastname: Iwamoto
authors.forename: N
authors.initials: N
authors.lastname: Yurino
authors.forename: S
authors.initials: S
authors.lastname: Fujii
authors.forename: N
authors.initials: N
authors.lastname: Murai
authors.forename: F
authors.initials: F
authors.lastname: Okuno
authors.forename: H
authors.initials: H
authors.lastname: Kotake
authors.forename: H
authors.initials: H
authors.lastname: Mashiba
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols; D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D016461:Chemoembolization, Therapeutic; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006499:Hepatic Artery; D006801:Humans; D007459:Iodized Oil / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000473:pathology*; D008175:Lung Neoplasms / Q000556:secondary* / Q000628:therapy; D016685:Mitomycin / Q000008:administration & dosage; D010844:Picibanil / Q000008:administration & dosage; D011379:Prognosis; D012074:Remission Induction; D012422:Rupture, Spontaneous; D005641:Tegafur / Q000008:administration & dosage; D014498:Uracil / Q000008:administration & dosage
chemical_list: D005641:Tegafur; D010844:Picibanil; D016685:Mitomycin; D014498:Uracil; D007459:Iodized Oil; D004317:Doxorubicin