[Informative value of complex electromyographic and immunologic examinations of patients with diabetic neuropathies].
As many as 43 patients suffering from diabetes mellitus associated with the clinical manifestations of diabetic neuropathy underwent ++clinico-electromyographic and immunologic examinations. The control group comprised 30 practically healthy persons of the same age. The electromyographic++ examination included measurements of the rate of wave spreading in motor fibers of the limb nerves in the distal and proximal parts (in accordance with the F-wave), a study of H-reflex from the musculus soleus of the leg together with M-response of hand and foot muscles. The immunologic examination consisted in measurements of different class immunoglobulins in the blood serum. Based on the electromyographic findings, 3 groups of patients were distinguished: group I included patients with primary injury to the myelin membrane of the nerves; group II was made up of patients with primary injury to the axon, and group III of patients with concomitant injury to the nervous membranes and axons. There was a significant elevation of the concentration of anti-myelin activity possessing IgM in the blood serum of patients belonging to groups I and III, which attests to the involvement of the immunopathological mechanism into myelopathy development.
Gorbacheva
F E
FE
Zinov'eva
O E
OE
Parfenov
V A
VA
D000328:Adult; D000368:Aged; D001132:Arm / Q000294:innervation*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000276:immunology; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000276:immunology; D003929:Diabetic Neuropathies / Q000175:diagnosis / Q000209:etiology*; D004576:Electromyography; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D007866:Leg / Q000294:innervation*; D008875:Middle Aged; D009132:Muscles / Q000294:innervation*; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis / Q000209:etiology*
D007136:Immunoglobulins
K otsenke informativnosti kompleksnogo élektromiograficheskogo i immunologicheskogo obsledovaniia bol'nykh diabeticheskoĭ nevropatieĭ.