Detection of bovine rhinotracheitis virus antibody by neutralizing test and ELISA in experimentally infected rabbits.
The antibody response of rabbit to infectious bovine rhinotracheitis (IBR) virus was examined. Two rabbits were inoculated with IBR virus strain Los Angeles into the trachea and intravenously, and intravenously two times, respectively. The patterns of antibody titers in the rabbits measured by neutralization test and ELISA were similar to those in the case of bovine. The antibody was detected after the inoculation, and much more antibody was detected after the second inoculation. The fact suggests that rabbits are a very useful laboratory animal for IBR virus infection studies.
Honda
E
E
Department of Veterinary Medicine, Faculty of Agriculture, Tokyo University of Agriculture and Technology, Japan.
Taniguchi
T
T
Watanabe
M
M
Kumagai
T
T
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D002417:Cattle; D004195:Disease Models, Animal; D004797:Enzyme-Linked Immunosorbent Assay; D007242:Herpesvirus 1, Bovine / Q000276:immunology*; D007241:Infectious Bovine Rhinotracheitis / Q000276:immunology*; D009500:Neutralization Tests; D011817:Rabbits
D000914:Antibodies, Viral