title: Immunohistochemical demonstration of papillomavirus infection in condylomatous and preneoplastic lesions of the lower female genital tract.
abstract: An immunoperoxidase study of 250 cases of condyloma of the female genital tract showed HPV expression in 45% of the cases. The flat form was the most frequent (191/250 cases). Condylomatous lesions were associated with dysplasia, in situ or micro-invasive carcinoma in 43% of the cases. The results support the role of the HPV as a possible carcinogenic agent in the female genital tract.
authors.affiliation: Department of Pathology, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Sâo Paulo, Brazil.
authors.forename: L A
authors.initials: LA
authors.lastname: Andrade
authors.forename: N
authors.initials: N
authors.lastname: Oyakawa
authors.forename: J
authors.initials: J
authors.lastname: Vassallo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000956:Antigens, Viral / Q000032:analysis*; D003218:Condylomata Acuminata / Q000382:microbiology*; D005260:Female; D005833:Genital Neoplasms, Female / Q000382:microbiology*; D006801:Humans; D007124:Immunoenzyme Techniques; D008875:Middle Aged; D027383:Papillomaviridae / Q000276:immunology*; D011230:Precancerous Conditions / Q000382:microbiology*; D014412:Tumor Virus Infections / Q000175:diagnosis*
chemical_list: D000956:Antigens, Viral