title: [Adaptation to short stress exposures prevents the enhancement of the endothelium-dependent reactions of the aorta in myocardial infarct].
abstract: Acute stress concomitant to the experimental myocardial infarction resulted in endothelial hyperactivation in the rat aorta as manifested in an increased inhibition of norepinephrine-induced contractions of smooth muscle, enhanced endothelium-dependent relaxation and a respective drop of the blood pressure. Preliminary adaptation of rats to short-term non-damaging stress exposure to a considerable extent prevented the stress-induced hyperactivation of endothelium and improved the postinfarction time course of the blood pressure.
authors.forename: A V
authors.initials: AV
authors.lastname: Lapshin
authors.forename: E B
authors.initials: EB
authors.lastname: Manukhina
authors.forename: F Z
authors.initials: FZ
authors.lastname: Meerson
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology*; D000818:Animals; D001011:Aorta / Q000187:drug effects / Q000503:physiopathology*; D001794:Blood Pressure / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004730:Endothelium, Vascular / Q000503:physiopathology*; D066298:In Vitro Techniques; D008297:Male; D009119:Muscle Contraction / Q000187:drug effects / Q000502:physiology; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000503:physiopathology; D009203:Myocardial Infarction / Q000503:physiopathology*; D009638:Norepinephrine / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D013312:Stress, Physiological / Q000503:physiopathology*; D013997:Time Factors
chemical_list: D009638:Norepinephrine
vernacular_title: Adaptatsiia k korotkim stressornym vozdeĭstviiam preduprezhdaet usilenie éndoteliĭzavisimykh reaktsiĭ aorty pri infarkte miokarda.