Distribution of type A and type B EBV in patients with nasopharyngeal carcinoma.
The subtypes of Epstein-Barr virus (EBV) according to EBNA 2 genes were investigated in 53 nasopharyngeal carcinoma (NPC) biopsies in Taiwan by polymerase chain reaction (PCR) and by Southern blot hybridization method. EBV DNA was found present in all NPC biopsies. Type A was the predominant type and comprised of 94.3% of the EBV of NPC. Type B or coinfection of type A and type B comprised of only 3.8% and 1.9% respectively.
Shu
C H
CH
Department of Otolaryngology, Veterans General Hospital-Taipei, R.O.C.
Liu
W T
WT
Chang
Y S
YS
Liang
C L
CL
Liu
S T
ST
Lin
C Z
CZ
Chang
P
P
D000328:Adult; D000368:Aged; D001483:Base Sequence; D002277:Carcinoma / Q000382:microbiology*; D004279:DNA, Viral / Q000032:analysis; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008875:Middle Aged; D008969:Molecular Sequence Data; D009303:Nasopharyngeal Neoplasms / Q000382:microbiology*; D016133:Polymerase Chain Reaction
D004279:DNA, Viral