Twenty-four hour intragastric acidity and plasma gastrin concentration profiles in female and male subjects.
1. Simultaneous 24 h intragastric acidity and plasma gastrin concentration profiles were determined in 35 healthy young women and 96 healthy young men. 2. The females had a consistently lower median hourly intragastric acidity, and a higher median hourly plasma gastrin concentration, throughout the 24 h. 3. The 24 h integrated intragastric acidity was significantly lower in the female group (females, 485 mmol.h.l-1; males, 842 mmol.h.l-1. P less than 0.001). The 24 h integrated plasma gastrin concentration was significantly higher in the female group (females, 407 pmol.h.l-1; males, 185 pmol.h.l-1; P less than 0.001).
Prewett
E J
EJ
University Department of Medicine, Royal Free Hospital School of Medicine, London.
Smith
J T
JT
Nwokolo
C U
CU
Sawyerr
A M
AM
Pounder
R E
RE
D000328:Adult; D001835:Body Weight; D002940:Circadian Rhythm; D005260:Female; D005745:Gastric Acidity Determination; D005750:Gastric Juice / Q000737:chemistry*; D005755:Gastrins / Q000097:blood*; D006801:Humans; D008297:Male; D012737:Sex Factors
D005755:Gastrins