[The effect of long-term venous hypertension on the macro- and microhemodynamics in the skeletal muscle].
Preliminary artificial venous hypertension of hindlimbs for 4-6 weeks was followed by comparison of resistive, capacitance and metabolic functions of the m. gastrocnemius' vessels performed in experimental and control cats with different levels of initial pressure of venous outflow. An increase of precapillary resistance, of the capillary filtration coefficient, a decrease of distensibility of the muscle venous bed, and constancy of postcapillary resistance and mean capillary pressure, were found in experimental animals. Mechanogenic responses of the muscle venous vessels to a rapid increase of the pressure in them were augmented in animals with chronic venous hypertension. The mechanisms of the effect of prolonged venous hypertension on functions of skeletal muscle's vessels, are discussed.
Kudriashov
Iu A
IuA
Talash
S A
SA
D000818:Animals; D002415:Cats; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006614:Hindlimb / Q000098:blood supply; D008026:Ligation; D008297:Male; D009132:Muscles / Q000098:blood supply* / Q000502:physiology; D013997:Time Factors; D014655:Vascular Resistance / Q000502:physiology; D014682:Vena Cava, Inferior; D014690:Venous Pressure / Q000502:physiology*
Vliianie dlitel'noĭ venoznoĭ gipertenzii na makro- i mikrogemodinamiku v skeletnoĭ myshtse.