[Eicosanoic acid levels in children with atopic dermatitis].
Column chromatography followed by RIA was used to measure the blood plasma content of arachidonic acid metabolites (leukotrienes C4, B4, C4/D4/E4, prostaglandins F2 alpha, E2, 6-keto-prostaglandin F1 alpha, thromboxane B2) in 146 children aged 6 months to 14 years with atopic dermatitis. The data obtained were compared to the healthy children's parameters. The majority of the patients manifested activation of the system of arachidonic acid metabolism. The intensity of changes in the content of eicosanoids was found to depend on the clinical pattern and spreading of skin lesions.
Vinogradov
A I
AI
Balabolkin
I I
II
Vinogradova
N A
NA
D015121:6-Ketoprostaglandin F1 alpha / Q000097:blood; D000293:Adolescent; D001095:Arachidonic Acids / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000097:blood*; D015237:Dinoprost / Q000097:blood; D015232:Dinoprostone / Q000097:blood; D006801:Humans; D007223:Infant; D007975:Leukotriene B4 / Q000097:blood; D013189:SRS-A / Q000097:blood; D013929:Thromboxane B2 / Q000097:blood
D001095:Arachidonic Acids; D013189:SRS-A; D007975:Leukotriene B4; D013929:Thromboxane B2; D015121:6-Ketoprostaglandin F1 alpha; D015237:Dinoprost; D015232:Dinoprostone
Soderzhanie éĭkozanoidov u deteĭ s atopicheskim dermatitom.