title: [Differential therapy of Gilles de la Tourette's syndrome].
abstract: The previous works of the author demonstrated the clinical heterogeneity of Gilles de la Tourette's syndrome (GTS). Based on statistical treatment of the efficacy of 138 courses of the treatment with benzodiazepine tranquilizers, neuroleptics, antidepressants, and anticonvulsants, methods of the individualized treatment of GTS were elaborated. It is recommended that low doses of neuroleptics (orap, haloperidol) be applied in patients with typical GTS. Schizophrenia associated with Tourette-like disorders requires the use of higher doses of neuroleptics and, in some cases, of the combined therapy. In encephalopathy accompanied by Tourette-like disorders, the treatment with anticonvulsants and benzodiazepine tranquilizers turned out most effective.
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Smirnov
mesh_terms: D000927:Anticonvulsants / Q000008:administration & dosage; D000928:Antidepressive Agents / Q000008:administration & dosage; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D006801:Humans; D019965:Neurocognitive Disorders / Q000150:complications / Q000188:drug therapy*; D011619:Psychotropic Drugs / Q000008:administration & dosage*; D012559:Schizophrenia / Q000150:complications / Q000188:drug therapy*; D012720:Severity of Illness Index; D005879:Tourette Syndrome / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D014149:Tranquilizing Agents / Q000008:administration & dosage
chemical_list: D000927:Anticonvulsants; D000928:Antidepressive Agents; D011619:Psychotropic Drugs; D014149:Tranquilizing Agents
vernacular_title: K differentsial'noĭ terapii sindroma Zhilia de lia Turetta.