title: The possible involvement of free radical scavenging properties in the actions of cytokines.
abstract: Among the cytokines which show an antiproliferative effect on certain tumor cells, we investigated the free radical scavenging properties of tumor necrosis factor-alpha, interferon-alpha, and interferon-gamma. The scavenging properties were determined in vitro by the ability to reduce DPPH free radicals. All of these cytokines exhibited marked DPPH free radical scavenging ability.
authors.affiliation: First Department of Surgery, Okayama University Medical School, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Matsubara
authors.forename: S
authors.initials: S
authors.lastname: Fuchimoto
authors.forename: H
authors.initials: H
authors.lastname: Iwagaki
authors.forename: Y
authors.initials: Y
authors.lastname: Nonaka
authors.forename: T
authors.initials: T
authors.lastname: Kimura
authors.forename: H
authors.initials: H
authors.lastname: Kashino
authors.forename: R
authors.initials: R
authors.lastname: Edamatsu
authors.forename: M
authors.initials: M
authors.lastname: Hiramatsu
authors.forename: K
authors.initials: K
authors.lastname: Orita
mesh_terms: D015764:Bepridil / Q000031:analogs & derivatives / Q000737:chemistry; D001713:Biphenyl Compounds; D016207:Cytokines / Q000737:chemistry*; D004578:Electron Spin Resonance Spectroscopy; D016166:Free Radical Scavengers; D007370:Interferon Type I / Q000737:chemistry; D007371:Interferon-gamma / Q000737:chemistry; D010851:Picrates; D014409:Tumor Necrosis Factor-alpha / Q000737:chemistry
chemical_list: D001713:Biphenyl Compounds; D016207:Cytokines; D016166:Free Radical Scavengers; D007370:Interferon Type I; D010851:Picrates; D014409:Tumor Necrosis Factor-alpha; D015764:Bepridil; D007371:Interferon-gamma; C004931:1,1-diphenyl-2-picrylhydrazyl