title: [The clinico-biochemical characteristics of persons with paraphilias and a chromosome anomaly (47, XYY)].
abstract: The authors describe the results of a comprehensive examination of 5 persons with chromosomal aberration (47, XYY) manifesting the signs of deviation from normal sexual behavior. The examined were shown to have common dysontogenesis that manifested itself by retardation of the biological basis of sexuality, psychosexual formation together with retardation of the mental processes on the whole. Whatever variants of deviations from normal sexual behavior the common feature was predominance in the libido structure of sadistic aims, that contributed to the revealing of aggressive sexual behavior. Material changes were discovered by radioimmunoassay in the function of the hypothalamohypophyseal and gonadal system in persons with the "YY syndrome". The levels of prolactin and luteinizing hormone along with the LH/FSH ratio appeared significantly elevated. Disorders were also identified in the hypothalamohypophyseal and thyroid system. It is assumed that the discovered changes influence the serotoninergic mechanisms by which aggressive and pathological sexual behavior is formed in such persons.
authors.forename: B V
authors.initials: BV
authors.lastname: Shostakovich
authors.forename: L K
authors.initials: LK
authors.lastname: Smirnova
authors.forename: A A
authors.initials: AA
authors.lastname: Tkachenko
authors.forename: M V
authors.initials: MV
authors.lastname: Usiukina
authors.forename: G P
authors.initials: GP
authors.lastname: Marinina
authors.forename: T N
authors.initials: TN
authors.lastname: Nikolaeva
mesh_terms: D012739:Gonadal Steroid Hormones / Q000097:blood; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007328:Insulin / Q000097:blood; D007621:Karyotyping; D008297:Male; D010262:Paraphilic Disorders / Q000097:blood*; D010907:Pituitary Hormones / Q000097:blood; D013963:Thyroid Hormones / Q000097:blood; D014997:XYY Karyotype / Q000097:blood*
chemical_list: D012739:Gonadal Steroid Hormones; D007328:Insulin; D010907:Pituitary Hormones; D013963:Thyroid Hormones; D006854:Hydrocortisone
vernacular_title: Kliniko-biokhimicheskie kharakteristiki lits s parafiliiami pri khromosomnoĭ anomalii (47, XYY).