title: [Initial results of the Project of the German Breast Cancer Study Group on "Breast saving therapy of the small breast cancer"].
abstract: In the German Breast Cancer Study Group (GBSG) multicenter trial "Breast preservation in small breast cancer" 1119 patients were accrued over a period of six years. The study was originally designed as a randomized trial which had to be changed into a prospective observation study. A high therapeutic standard was guaranteed by quality control. The univariate analysis of prognostic variables was the first step to a valid treatment comparison. Those factors determined as being significant were combined with the treatment effects in a multivariate analysis. The published results were obtained after a median observation time of four years.
authors.affiliation: Chirurgische Universitätsklinik Göttingen.
authors.forename: H F
authors.initials: HF
authors.lastname: Rauschecker
authors.forename: W
authors.initials: W
authors.lastname: Gatzemeier
authors.forename: R
authors.initials: R
authors.lastname: Sauer
authors.forename: M H
authors.initials: MH
authors.lastname: Seegenschmiedt
authors.forename: A
authors.initials: A
authors.lastname: Schauer
authors.forename: L
authors.initials: L
authors.lastname: Ummenhofer
authors.forename: W
authors.initials: W
authors.lastname: Sauerbrei
authors.forename: C
authors.initials: C
authors.lastname: Schmoor
authors.forename: M
authors.initials: M
authors.lastname: Schumacher
mesh_terms: D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D015412:Mastectomy, Segmental / Q000379:methods*; D008875:Middle Aged; D009367:Neoplasm Staging; D009376:Neoplasms, Hormone-Dependent / Q000401:mortality / Q000473:pathology / Q000601:surgery; D011446:Prospective Studies; D011879:Radiotherapy Dosage; D011960:Receptors, Estrogen / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis; D015996:Survival Rate
chemical_list: D011960:Receptors, Estrogen; D011980:Receptors, Progesterone
vernacular_title: Erste Ergebnisse des Projekts der Deutschen Brustkrebs-Studiengruppe (GBSG) zur "Brusterhaltenden Therapie des kleinen Mammacarcinoms".