[A mathematical model of the role of Ca2+/calmodulin-dependent protein kinase in the long term increase in effectiveness of synaptic plasticity].
A mathematical model describing initiation and restoring of the long-term potentiation (LTP) is proposed. This model is based on an assumption that Ca2+/Calmodulin-dependent protein kinase from some of second messengers exists in a number of states. The protein kinase ability for securing LTP restoring is connected with autophosphorylation.
Murzina
G B
GB
D017871:Calcium-Calmodulin-Dependent Protein Kinases; D004789:Enzyme Activation; D008962:Models, Theoretical; D010766:Phosphorylation; D011494:Protein Kinases / Q000378:metabolism / Q000502:physiology*; D015290:Second Messenger Systems; D013569:Synapses / Q000502:physiology*
D011494:Protein Kinases; D017871:Calcium-Calmodulin-Dependent Protein Kinases
Matematicheskaia model' roli Ca2+/kal'modulinzavisimoĭ proteinkinazy vdlitel'nom uvelichenii éffektivnosti sinapitcheskoĭ plastichnosti.