title: An ion-storage time-of-flight mass spectrometer for analysis of electrospray ions.
abstract: A preliminary design and implementation of a novel approach to electrospray-mass spectrometry are described. Based on a time-of-flight mass analysis, the instrument provides several important advantages for on-line mass analysis: 1, simplicity, ease of use and low manufacturing cost; 2, rapid scan speed, yielding quasi-instantaneous full mass scans at repetition rates up to several kHz; 3, soft ionization and accurate mass determination of extremely large analyte molecules; 4, high sensitivity.
authors.affiliation: Dept. of Chemical Engineering, Yale University, New Haven, CT 06520.
authors.forename: J G
authors.initials: JG
authors.lastname: Boyle
authors.forename: C M
authors.initials: CM
authors.lastname: Whitehouse
authors.forename: J B
authors.initials: JB
authors.lastname: Fenn
mesh_terms: D001120:Arginine / Q000737:chemistry; D016572:Cyclosporine / Q000737:chemistry; D003574:Cytochrome c Group / Q000737:chemistry; D013058:Mass Spectrometry / Q000295:instrumentation*; D008970:Molecular Weight
chemical_list: D003574:Cytochrome c Group; D016572:Cyclosporine; D001120:Arginine