title: Reactivity of monoclonal antibodies to the 41-kilodalton protein of porcine group C rotavirus with homologous and heterologous rotavirus serogroups in immunofluorescence tests.
abstract: Three monoclonal antibodies (MAbs) to porcine group C rotavirus immunoprecipitated the major inner capsid protein (41 kDa) but failed to precipitate group A rotavirus proteins. In immunofluorescence tests of rotavirus-infected cell cultures or pig intestines, the MAbs recognized porcine and bovine group C rotaviruses but not group A or B rotaviruses. These MAbs may recognize the group C rotavirus counterpart to VP6 of group A rotaviruses and may be useful as diagnostic reagents.
authors.affiliation: Department of Veterinary Microbiology and Parasitology, University of Ibadan, Nigeria.
authors.forename: C K
authors.initials: CK
authors.lastname: Ojeh
authors.forename: B M
authors.initials: BM
authors.lastname: Jiang
authors.forename: H
authors.initials: H
authors.lastname: Tsunemitsu
authors.forename: S Y
authors.initials: SY
authors.lastname: Kang
authors.forename: P A
authors.initials: PA
authors.lastname: Weilnau
authors.forename: L J
authors.initials: LJ
authors.lastname: Saif
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D000918:Antibody Specificity; D002213:Capsid / Q000737:chemistry / Q000276:immunology*; D005260:Female; D005455:Fluorescent Antibody Technique; D051379:Mice; D008970:Molecular Weight; D012401:Rotavirus / Q000145:classification / Q000276:immunology*; D012400:Rotavirus Infections / Q000276:immunology; D012703:Serotyping; D013552:Swine
chemical_list: D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral