Reverse gyrase in thermophilic eubacteria.
The presence of reverse gyrase, an unusual ATP-dependent type I topoisomerase first isolated from thermophilic archaebacteria, has been detected in four strains of Thermotogales, an order of extremely thermophilic eubacteria. This result suggests that reverse gyrase plays a key role in high-temperature-living organisms, independently of the evolutionary kingdom to which they belong.
Bouthier de la Tour
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Laboratoire d'Enzymologie des Acides Nucléiques, URA 554 Centre National de la recherche Scientifique, Université Pierre et Marie Curie, Paris, France.
Portemer
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Huber
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Forterre
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Duguet
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D001105:Archaea / Q000201:enzymology*; D004264:DNA Topoisomerases, Type I; D004250:DNA Topoisomerases, Type II / Q000737:chemistry / Q000302:isolation & purification*; D004269:DNA, Bacterial / Q000737:chemistry; D004278:DNA, Superhelical / Q000737:chemistry; D013696:Temperature
D004269:DNA, Bacterial; D004278:DNA, Superhelical; C041813:DNA reverse gyrase; D004264:DNA Topoisomerases, Type I; D004250:DNA Topoisomerases, Type II