[The role of phagocytic cells in the pathogenesis of idiopathic fibrosing alveolitis].
The paper deals with the examination of the role of phagocytes--alveolar macrophages and neutrophils--and peripheral monocytes, in the pathogenesis of idiopathic fibrosing alveolitis (IFA). As the disease aggravates, activation of the absorbing capacity of monocyte-macrophagal cells corresponds to a sharp rise in the level of circulating immune complexes in the blood of IFA patients. Higher activities of elastase and collagenase are observed in the IFA patients' bronchial lavage fluid.
Pokhodzeĭ
I V
IV
Bulychev
A G
AG
Ses'
T P
TP
Leont'eva
E A
EA
D000328:Adult; D000936:Antigen-Antibody Complex / Q000032:analysis; D001992:Bronchoalveolar Lavage Fluid / Q000201:enzymology; D005260:Female; D006801:Humans; D008297:Male; D003012:Microbial Collagenase / Q000378:metabolism; D008875:Middle Aged; D010196:Pancreatic Elastase / Q000378:metabolism; D010586:Phagocytes / Q000502:physiology*; D011658:Pulmonary Fibrosis / Q000209:etiology* / Q000276:immunology
D000936:Antigen-Antibody Complex; D010196:Pancreatic Elastase; D003012:Microbial Collagenase
Rol' fagotsitiruiushchikh kletok v patogeneze idiopaticheskogo fibroziruiushchego al'veolita.