Multiple hereditary trichoepithelioma and cylindroma (Brooke-Spiegler syndrome).
Three cases of trichoepithelioma associated with cylindroma (Brooke-Spiegler syndrome) in the same family are reported. Three generations were affected. The syndrome usually beginning at puberty is inherited as an irregular autosomal dominant trait.
Delfino
M
M
Department of Dermatology, University of Naples, Italy.
D'Anna
F
F
Ianniello
S
S
Donofrio
V
V
D000328:Adult; D000368:Aged; D003528:Carcinoma, Adenoid Cystic / Q000150:complications / Q000235:genetics / Q000473:pathology*; D005153:Facial Neoplasms / Q000150:complications / Q000235:genetics / Q000473:pathology*; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D009386:Neoplastic Syndromes, Hereditary / Q000150:complications / Q000235:genetics / Q000473:pathology*; D010375:Pedigree; D009626:Terminology as Topic