title: Reservoir of quinolone residues in fish.
abstract: Different tissues from salmon treated with the quinolones oxolinic acid, flumequine, enrofloxacin and sarafloxacin were analysed in search of possible reservoirs of the drugs. Residues of oxolinic acid and flumequine seem to be especially bound to bone, enrofloxacin to skin, and sarafloxacin to both skin and bone. The results showed that residues of these drugs were present in the fish for prolonged periods after the end of treatment.
authors.affiliation: Department of Food Hygiene, Norwegian College of Veterinary Medicine, Oslo.
authors.forename: I
authors.initials: I
authors.lastname: Steffenak
authors.forename: V
authors.initials: V
authors.lastname: Hormazabal
authors.forename: M
authors.initials: M
authors.lastname: Yndestad
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D000818:Animals; D001842:Bone and Bones / Q000378:metabolism; D004350:Drug Residues / Q000032:analysis / Q000493:pharmacokinetics*; D024841:Fluoroquinolones; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D010093:Oxolinic Acid / Q000032:analysis / Q000493:pharmacokinetics; D011807:Quinolizines / Q000032:analysis / Q000493:pharmacokinetics; D015363:Quinolones / Q000032:analysis / Q000493:pharmacokinetics*; D012474:Salmon / Q000378:metabolism*; D012867:Skin / Q000378:metabolism; D014018:Tissue Distribution
chemical_list: D024841:Fluoroquinolones; D011807:Quinolizines; D015363:Quinolones; D010093:Oxolinic Acid; C012976:flumequine