[The role of circulating immune complexes and the status of argyrophilic membranes of the vascular walls in the development of brain edema in patients with meningococcal meningoencephalitis].
Based on clinical and immunological examinations of 60 patients with MME and 30 normal persons, the dynamics of the blood CIC content was studied depending on the time and gravity of the disease. The discovered changes in argyrophilic membranes of the vascular walls are determined to a considerable measure by the pathogenic action of CIC on microvessels, which entails the derangement of blood-brain barrier function and contributes to the development of acute purulent meningitis.
Gebesh
V V
VV
Iarosh
O A
OA
D000293:Adolescent; D000328:Adult; D000368:Aged; D000936:Antigen-Antibody Complex / Q000032:analysis*; D001929:Brain Edema / Q000175:diagnosis / Q000209:etiology*; D002199:Capillary Permeability / Q000502:physiology; D002536:Cerebral Arteries / Q000187:drug effects / Q000503:physiopathology*; D006801:Humans; D007105:Immune Complex Diseases / Q000175:diagnosis / Q000209:etiology*; D008589:Meningococcal Infections / Q000150:complications / Q000503:physiopathology*; D008590:Meningoencephalitis / Q000150:complications / Q000503:physiopathology*; D008875:Middle Aged; D012835:Silver Nitrate / Q000493:pharmacokinetics
D000936:Antigen-Antibody Complex; D012835:Silver Nitrate
Rol' tsirkuliruiushchikh immunnykh kompleksov i sostoianiia argirofil'nykh membran sosudistykh stenok v razvitii oteka mozga u bol'nykh meningokokkovym meningoéntsefalitom.