title: Models of repression of transposition in P-M hybrid dysgenesis by P cytotype and by zygotically encoded repressor proteins.
abstract: By analytical theory and computer simulation the expected evolutionary dynamics of P transposable element spread in an infinite population are investigated. The analysis is based on the assumption that, unlike transposable elements which move via RNA intermediates, the harmful effects of P elements arise primarily in the act of transposition, and that this causes their evolutionary dynamics to be unusual. It is suggested that a situation of transposition-selection balance will be superceded by the buildup of a cytoplasmically inherited repression or by the elimination of active transposase-encoding elements from the chromosomes, a process which may be accompanied by the evolution of elements which encode proteins which repress transposition.
authors.affiliation: Department of Genetics, University of Nottingham, Queens Medical Centre, England.
authors.forename: J F
authors.initials: JF
authors.lastname: Brookfield
mesh_terms: D000818:Animals; D005075:Biological Evolution; D003198:Computer Simulation; D004251:DNA Transposable Elements; D006824:Hybridization, Genetic; D008433:Mathematics; D008957:Models, Genetic; D012097:Repressor Proteins / Q000235:genetics*
chemical_list: D004251:DNA Transposable Elements; D012097:Repressor Proteins