[Severe encephalopathy in Schönlein-Henoch purpura (case report)].
We are reporting on the case of a 7-year old, previously healthy boy with Schönlein-Henoch Purpura complicated by a severe encephalopathy: Two days after the initial abdominal symptoms he showed a prolonged cerebral convulsion followed by a 6-day semicomatous state, right-sided paralysis and aphasia. The typical skin lesions and joint swellings only appeared two days after the seizure. He was treated with acyclovir, followed by beta-interferon, both without apparent improvement. After initiating corticosteroids improvement of the neurological deficits was noticed. After 3 1/2 months he was still left with a right-sided spastic paralysis and mild aphasia. The cranial CT demonstrated initially a left-sided cerebral edema, later developing into a cerebral atrophy involving the periventricular structures as well as cortical regions predominantly of the left side.
Kinderklinik, Leopoldina-Krankenhaus der Stadt Schweinfurt.
S
S
Fösel
H
H
Artmann
D000212:Acyclovir / Q000008:administration & dosage; D001037:Aphasia / Q000175:diagnosis; D001284:Atrophy; D001921:Brain / Q000473:pathology; D001925:Brain Damage, Chronic / Q000175:diagnosis*; D002648:Child; D004569:Electroencephalography; D006429:Hemiplegia / Q000175:diagnosis*; D006801:Humans; D011695:IgA Vasculitis / Q000175:diagnosis* / Q000628:therapy; D007370:Interferon Type I / Q000008:administration & dosage; D008297:Male; D013226:Status Epilepticus / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed
D007370:Interferon Type I; D000212:Acyclovir
Schwere Encephalopathie bei Purpura Schönlein-Henoch (Fallbericht).