Normal biochemistry values in baboons (Papio C. cinocephalus).
1. Analysis of biochemical parameters was carried out on material pooled from 10 baboons, adult male and female, of the Papio c. cinocephalus strain. 2. The values determined were for the common metabolites and enzymes utilized for specific studies in general metabolism (urea, glucose, cholesterol, phospholipids, bilirubin, uric acid, creatinine, alkaline phosphatase, glutamic oxaloacetic transaminase, glutamic pyruvic transaminase, lactic dehydrogenase, leucine amino peptidase, gamma glutamyl transpeptidase, total creatine kinase and amylase). Total protein and its fractions (ratio albumin/globulin, albumin, alpha 1-globulin and alpha 2-globulin) were also determined. 3. Results of these studies were compared with values for normal human adults. 4. The differences obtained between the respective ranges can be explained by the different physiology of the two species and, possibly, may also be caused by the use of human substrates in the enzyme assays. 5. Through the determination of normal values for the baboon, this study provides values for this species as an experimental animal in biomedical research.
Departamento de Medicina y Cirugía Experimental, Hospital General Gregorio Marañón, Madrid, Spain.
M J
MJ
Cano
M
M
Desco
P
P
Garcia-Barreno
D000469:Alkaline Phosphatase / Q000097:blood; D000681:Amylases / Q000097:blood; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D002784:Cholesterol / Q000097:blood; D003402:Creatine Kinase / Q000097:blood; D005260:Female; D006801:Humans; D007931:Leucyl Aminopeptidase / Q000097:blood; D008297:Male; D010215:Papio / Q000097:blood*; D012016:Reference Values; D014508:Urea / Q000097:blood; D014527:Uric Acid / Q000097:blood
D001786:Blood Glucose; D014527:Uric Acid; D014508:Urea; D002784:Cholesterol; D003402:Creatine Kinase; D000469:Alkaline Phosphatase; D000681:Amylases; D007931:Leucyl Aminopeptidase