Assignment by in situ hybridization of a fibroblast growth factor receptor gene to human chromosome band 10q26.
A 2.3-kb cDNA probe for the human bek fibroblast growth factor receptor was used to determine the chromosomal localization of the corresponding gene by in situ hybridization. The results show that this gene, a form of which is amplified in some poorly differentiated stomach cancers, is localized on chromosome region 10q26. The two previously identified fibroblast growth factor receptor genes are thus not on the same chromosome, as the related flg ("fms-like gene") fibroblast growth factor receptor gene has previously been mapped to human chromosome region 8p12.
INSERM Unité 242, Hôpital d'Enfants, Groupe Hospitalier de la Timone,Marseille, France.
M G
MG
Mattei
A
A
Moreau
M C
MC
Gesnel
E
E
Houssaint
R
R
Breathnach
D001345:Autoradiography; D002871:Chromosome Banding; D002879:Chromosomes, Human, Pair 10; D004247:DNA / Q000235:genetics; D015342:DNA Probes; D005346:Fibroblast Growth Factors / Q000235:genetics*; D000091344:Filaggrin Proteins; D006801:Humans; D007621:Karyotyping; D009693:Nucleic Acid Hybridization; D012150:Polymorphism, Restriction Fragment Length; D011956:Receptors, Cell Surface / Q000235:genetics*; D017468:Receptors, Fibroblast Growth Factor
D015342:DNA Probes; C000717249:FLG protein, human; D000091344:Filaggrin Proteins; D011956:Receptors, Cell Surface; D017468:Receptors, Fibroblast Growth Factor; D005346:Fibroblast Growth Factors; D004247:DNA