[Alpha-mimetic effects on nasal mucosa in magnetic resonance tomography].
The effect of xylometazolin spray (OTRIVEN) on the nasal mucosa was tested on persons with and without clinical signs of rhinitis and sinusitis. MRI is an excellent means to show the decongestive effect. The reaction is chiefly seen at the inferior and middle nasal concha and becomes manifest in a few minutes. No significant effect is noticeable at the maxillary sinus mucosa and infiltrated ethmoidal sinus. Generally, it is possible to show and examine the pharmacological effects that change the size and the liquid consistency of organs.
Radiologische Abteilung, Akademisches Lehrkrankenhaus, Technischen Universität München.
M
M
Benammar-Englmaier
J K
JK
Hallermeier
B
B
Englmaier
D000281:Administration, Intranasal; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage*; D008279:Magnetic Resonance Imaging; D014663:Nasal Decongestants; D009297:Nasal Mucosa / Q000187:drug effects* / Q000473:pathology; D010256:Paranasal Sinuses / Q000187:drug effects / Q000473:pathology; D012220:Rhinitis / Q000188:drug therapy*; D012852:Sinusitis / Q000188:drug therapy*
D007093:Imidazoles; D014663:Nasal Decongestants; C009695:xylometazoline
Alphamimetische Wirkungen an der Nasenschleimhaut im MR-Tomogramm.