Inhibitory effects of a platelet activating factor-antagonist 48740RP in cyclosporin-induced nephrotoxicity in the rat as assessed by renal glutathione metabolism parameters.
Massicot
F
F
Laboratoire de Toxicologie, Faculté de Pharmacie, Paris, France.
Pham Huy
C
C
Martin
C
C
Thevenin
M
M
Warnet
J M
JM
Claude
J R
JR
D000626:Aminopeptidases / Q000378:metabolism; D000818:Animals; D001806:Blood Urea Nitrogen; D018826:CD13 Antigens; D003404:Creatinine / Q000097:blood; D016572:Cyclosporine / Q000633:toxicity*; D005978:Glutathione / Q000378:metabolism*; D007668:Kidney / Q000187:drug effects* / Q000378:metabolism; D007672:Kidney Cortex / Q000187:drug effects / Q000378:metabolism; D010972:Platelet Activating Factor / Q000037:antagonists & inhibitors*; D011725:Pyridines / Q000494:pharmacology*; D051381:Rats; D013844:Thiazoles / Q000494:pharmacology*
D010972:Platelet Activating Factor; D011725:Pyridines; D013844:Thiazoles; D016572:Cyclosporine; C052520:3-(3-pyridinyl)-1H,3H-pyrrolo(1,2-c)thiazole-7-carboxamide; D003404:Creatinine; D000626:Aminopeptidases; D018826:CD13 Antigens; D005978:Glutathione