The agonist pharmacophore of the benzodiazepine receptor. Synthesis of a selective anticonvulsant/anxiolytic.
Diaz-Arauzo
H
H
Department of Chemistry, University of Wisconsin--Milwaukee 53201.
Evoniuk
G E
GE
Skolnick
P
P
Cook
J M
JM
D000818:Animals; D014151:Anti-Anxiety Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D000927:Anticonvulsants / Q000138:chemical synthesis* / Q000494:pharmacology; D002243:Carbolines / Q000138:chemical synthesis* / Q000494:pharmacology; D051379:Mice; D011963:Receptors, GABA-A / Q000187:drug effects*
D014151:Anti-Anxiety Agents; D000927:Anticonvulsants; D002243:Carbolines; D011963:Receptors, GABA-A; C068884:6-propoxy-4-(methoxymethyl)-beta-carboline-3-carboxylic acid ethyl ester; C042569:ZK 93423