Lethal body burden of triphenyltin chloride in fish: preliminary results.
1. Guppies exposed to several triphenyltin chloride (TPTC) concentrations in water died as soon as a body burden of 20 +/- 10 nmol/g fish was reached. 2. Accumulation of TPTC during exposure in acute toxicity experiments can be predicted by using the kinetic parameters of TPTC. 3. The lethal body burden is two orders of magnitude lower than for narcotic organic compounds such as chlorobenzenes.
Research Institute of Toxicology, University of Utrecht, The Netherlands.
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D000818:Animals; D001822:Body Burden; D007928:Lethal Dose 50; D009947:Organotin Compounds / Q000493:pharmacokinetics*; D011036:Poecilia / Q000378:metabolism*; D014874:Water Pollutants, Chemical / Q000493:pharmacokinetics*
D009947:Organotin Compounds; D014874:Water Pollutants, Chemical; C012594:triphenyltin chloride