Successful treatment for perinephric abscess with recombinant human granulocyte colony-stimulating factor following nephrectomy in a patient of myelodysplastic syndrome: a case report.
The 35-year-old man with myelodysplastic syndrome (MDS) and granulocytopenia with dry cough and high fever was eventually found to have a left perinephric abscess of Staphylococcus aureus. He underwent left nephrectomy and drainage of perinephric space in conjunction with appropriate antibiotics. However, because of persistent granulocytopenia, Staph. aureus never cleared up with formation of only poor granulation. Recombinant human granulocyte colony-stimulating factor (G-CSF) was added to the above treatment leading to prompt improvement in granulocytopenia and emergence of the good granulation tissue. G-CSF will probably become one of the important agents in treating MDS with granulocytopenia.
Department of Internal Medicine, Miyazaki Prefectural Hospital, Japan.
K
K
Tamura
M
M
Takeuchi
N
N
Hirakawa
K
K
Toyoda
M
M
Minoda
D000038:Abscess / Q000188:drug therapy* / Q000209:etiology; D000328:Adult; D004341:Drug Evaluation; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use*; D006098:Granulocytes / Q000502:physiology; D006801:Humans; D007674:Kidney Diseases / Q000188:drug therapy*; D008297:Male; D009190:Myelodysplastic Syndromes / Q000150:complications* / Q000601:surgery; D009392:Nephrectomy; D009503:Neutropenia / Q000209:etiology; D011994:Recombinant Proteins / Q000627:therapeutic use
D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor