[A case of hepatocellular carcinoma in an elderly patient that improved upon combination therapy of Lentinan and Tegafur].
The case was an 83-year-old man whose chief complaint was right-hypochondralgia and high fever. His laboratory findings at the first visit revealed liver dysfunction and an elevation of AFP level. Abdominal ultra-sonography revealed a giant tumor in his liver. Because of his advanced age and the large size of his tumor, he was given 2 mg Lentinan a week and 750 mg Tegafur every day. After 3 months his serum AFP level decreased to normal range, and on computed tomography his tumor disappeared completely 6 months after the beginning of this therapy. We recommend the combination therapy of Lentinan and Tegafur for patients with a high risk for usual therapies like this case for their quality of life.
Takahashi
T
T
2nd Dept. of Medicine, Hokkaido University, School of Medicine, Sapporo, Japan.
Hori
Y
Y
Isogawa
S
S
Saho
M
M
Yoshida
H
H
Yokoyama
K
K
Watanabe
M
M
Nakagawa
S
S
D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D006528:Carcinoma, Hepatocellular / Q000097:blood / Q000188:drug therapy*; D006801:Humans; D007912:Lentinan / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000097:blood / Q000188:drug therapy*; D008297:Male; D012074:Remission Induction; D005641:Tegafur / Q000008:administration & dosage; D000509:alpha-Fetoproteins / Q000378:metabolism
D000509:alpha-Fetoproteins; D005641:Tegafur; D007912:Lentinan