The effect of repeated oral doses of lornoxicam on antipyrine elimination in normal human volunteers.
Treatment with lornoxicam 4 mg twice daily for 14 d did not produce any change in salivary antipyrine elimination in 11 of 12 healthy volunteers. Anomalous results in one subject are presented and discussed.
Ravic
M
M
Department of Clinical Pharmacology, St. Bartholomew's Hospital, London, UK.
Johnston
A
A
Turner
P
P
Takacs
F
F
Rosenow
D E
DE
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage* / Q000494:pharmacology; D000983:Antipyrine / Q000493:pharmacokinetics*; D005260:Female; D006801:Humans; D008297:Male; D010894:Piroxicam / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D012463:Saliva / Q000737:chemistry
D000894:Anti-Inflammatory Agents, Non-Steroidal; D010894:Piroxicam; C059451:lornoxicam; D000983:Antipyrine