[Increased leukopoietic effect of 2-cyanoethylurea by doubling the oxygen concentration of the air].
In Wistar rats the sure leukopoietic effect of 165 mg/kg-1 of 2-cyanethylurea was found to be increased distinctly and in some cases significantly by doubling the O2 shares of inhaling air to 42%. Small lymphocytes are the main carrier of this effect. The potential immunological relevance of the findings is referred to.
Forschungsinstitut Manfred von Ardenne, Dresden.
M
M
von Ardenne
P G
PG
Reitnauer
J
J
Fleischer
D000818:Animals; D004920:Erythropoiesis / Q000187:drug effects; D006410:Hematopoiesis / Q000187:drug effects*; D007962:Leukocytes / Q000502:physiology*; D008297:Male; D051381:Rats; D014508:Urea / Q000031:analogs & derivatives* / Q000494:pharmacology
C033054:2-cyanoethylurea; D014508:Urea
Erhöhte leukopoetische Wirkung von 2-Cyanethylharnstoff bei verdoppeltem Sauerstoffanteil der Luft.