Transposition of genes encoding kanamycin, neomycin and streptomycin resistance in Staphylococcus aureus.
The determinants encoding resistance to kanamycin, neomycin and streptomycin on plasmid pWBG628 have been shown to undergo recombination independent transposition to the chromosome of Staphylococcus aureus. Transposition of the determinants to a target plasmid corresponded to transfer of a 4.5 kb element which has been designated Tn3854.
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School of Medical Technology, Curtin University of Technology, Perth, Western Australia.
Grubb
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D004251:DNA Transposable Elements; D004352:Drug Resistance, Microbial / Q000235:genetics; D005798:Genes, Bacterial / Q000235:genetics*; D006801:Humans; D007612:Kanamycin; D007613:Kanamycin Resistance / Q000235:genetics; D009355:Neomycin; D010957:Plasmids / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length; D013211:Staphylococcus aureus / Q000235:genetics*; D013307:Streptomycin
D004251:DNA Transposable Elements; D007612:Kanamycin; D009355:Neomycin; D013307:Streptomycin