Cutaneous neonatal neuroblastoma: report of a case.
We herein report a case of neonatal neuroblastoma with cutaneous metastasis. This newborn male was a full-term infant of a G3P3 mother. Asphyxia occurred immediately after birth, though he was revived after intensive medical treatment. Physical examination revealed multiple firm cutaneous nodules distributed over his body. In addition, congenital glaucoma, hepatomegaly, and a soft tissue mass along the right temporal bone were also observed. Laboratory data revealed markedly elevated urinary vanilmandelic acid excretion, leukopenia, thrombocytopenia and an increased level of SGOT and SGPT. A skin biopsy was performed on a cutaneous nodule on the right hip, and the histopathological picture confirmed the diagnosis of neuroblastoma. The patient expired 12 days after birth due to complications caused by his condition.
Kao
C H
CH
Department of Dermatology, Kaohsiung Medical College, Taiwan, R.O.C.
Yu
H S
HS
D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009447:Neuroblastoma / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*