Aphasia in left-handers. Comparison of aphasia profiles and language recovery in non-right-handed and matched right-handed patients.
The present retrospective analysis reports two studies. In Study 1, clinical aspects of aphasia are compared in right-handed (RH) and non-right-handed (NRH) patients; in Study 2, recovery from aphasia is compared in RH and NRH aphasic patients with a minimum of 5 months of daily language rehabilitation. From a continuous series of 1200 brain-damaged subjects, 24 NRH patients with a vascular lesion documented by computerized tomography were selected. In 19 cases the lesion was in the left hemisphere and in 5 cases in the right hemisphere. For 14 NRH patients, a RH subject with similar lesion, matched for age, education, length of illness, etiology (ischemic vs. hemorrhagic), and, when possible, sex was found. Presence and type of aphasia were compared in the two patients of the same pair and were found similar except for Pair 14; the RH subject had global aphasia and the NRH had conduction-like aphasia. Fifteen NRH patients were rehabilitated and reexamined at least 5 months after the first examination. Recovery of the 12 patients with a left-hemisphere lesion was compared with recovery of a group of RH subjects and no significant differences were found. Recovery of the three patients with right-hemisphere lesions is described. It is concluded that differences in type of aphasia and recovery between RHs and NRHs have been overemphasized in the past and must be reconsidered.
Basso
A
A
Clinic for Nervous Diseases, Milan University, Italy.
Farabola
M
M
Grassi
M P
MP
Laiacona
M
M
Zanobio
M E
ME
D000328:Adult; D000368:Aged; D001037:Aphasia / Q000534:rehabilitation*; D001039:Aphasia, Broca / Q000534:rehabilitation; D001041:Aphasia, Wernicke / Q000534:rehabilitation; D001072:Apraxias / Q000534:rehabilitation; D001925:Brain Damage, Chronic / Q000534:rehabilitation*; D002543:Cerebral Hemorrhage / Q000534:rehabilitation*; D002544:Cerebral Infarction / Q000534:rehabilitation*; D004292:Dominance, Cerebral; D005260:Female; D005500:Follow-Up Studies; D007839:Functional Laterality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests