Pseudoknots: a new motif in the RNA game.
In the last few years a novel RNA folding principle called pseudoknotting has emerged. Originally discovered in noncoding regions of plant viral RNAs, pseudoknots now appear to be a widespread structural motif in a number of functionally different RNAs. These structural elements are part of tRNA-like structures and are involved in folding catalytic sites of ribozymes. They increase the efficiency of ribosomal frameshifting or can serve as specific binding sites for regulatory proteins.
Pleij
C W
CW
Department of Biochemistry, University of Leiden, The Netherlands.
D001483:Base Sequence; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D012313:RNA; D016337:RNA, Catalytic; D012333:RNA, Messenger; D012335:RNA, Ribosomal; D012343:RNA, Transfer
D016337:RNA, Catalytic; D012333:RNA, Messenger; D012335:RNA, Ribosomal; D012313:RNA; D012343:RNA, Transfer