Comparison of the detoxification courses of the histamine-sensitizing, lymphocytosis-promoting and CHO cell-clustering activities in the process of the production of acellular pertussis vaccine.
Department of General Biologics Control, National Institute of Health, Tokyo, Japan.
S
S
Iwasa
H
H
Fujiwara
D000818:Animals; D001681:Biological Assay; D002449:Cell Aggregation / Q000187:drug effects; D005557:Formaldehyde; D006636:Histamine Release / Q000187:drug effects; D008218:Lymphocytosis / Q000139:chemically induced; D051379:Mice; D010567:Pertussis Vaccine / Q000302:isolation & purification* / Q000633:toxicity
D010567:Pertussis Vaccine; D005557:Formaldehyde