Children born after their fathers had been treated with chemotherapy for testicular cancer.
Twenty children fathered by 15 patients treated with platinum-based combination chemotherapy for disseminated testicular carcinoma were examined and found to have no evidence of congenital malformations. The results indicate no reason for advising against pregnancies in this group of young couples.
van der Kolk
B M
BM
Department of Medical Oncology, University Hospital Groningen, The Netherlands.
Mulder
N H
NH
Mantingh
A
A
van den Berg
E
E
Schraffordt Koops
H
H
de Vries
E G
EG
Willemse
P H
PH
Sleijfer
D T
DT
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000627:therapeutic use; D002945:Cisplatin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome; D013736:Testicular Neoplasms / Q000188:drug therapy*; D014747:Vinblastine / Q000627:therapeutic use
D001761:Bleomycin; D014747:Vinblastine; D002945:Cisplatin