Observations on the mechanism of action of FK-506. A pharmacologic probe of lymphocyte signal transduction.
Department of Immunology Research, Merck, Sharp & Dohme Research Laboratories, Rahway, NJ 07065.
N H
NH
Sigal
J J
JJ
Siekierka
F J
FJ
Dumont
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000633:toxicity; D002460:Cell Line; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D008213:Lymphocyte Activation / Q000187:drug effects; D008214:Lymphocytes / Q000187:drug effects* / Q000378:metabolism; D008222:Lymphokines / Q000378:metabolism; D008954:Models, Biological; D015398:Signal Transduction / Q000187:drug effects*; D016559:Tacrolimus
D000900:Anti-Bacterial Agents; D007166:Immunosuppressive Agents; D008222:Lymphokines; D016559:Tacrolimus