The role of the streptococcus in poststreptococcal reactive arthritis and childhood polyarteritis nodosa.
Poststreptococcal reactive arthritis is most likely a form of acute rheumatic fever. However, it frequently differs by early development of arthritis after pharyngitis, more prolonged arthritis or arthralgia and a less dramatic response to aspirin. The use of prophylactic penicillin is discussed and advocated. Childhood polyarteritis may be divided into a cutaneous form and a more generalized form that usually involves the kidney but frequently also the gastrointestinal tract, heart, or nervous system. Nine children with polyarteritis nodosa are described and their disease related to a prior streptococcal infection.
University of Texas Southwestern Medical Center, Dallas 75235-9063.
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D000208:Acute Disease; D001170:Arthritis, Infectious / Q000188:drug therapy / Q000382:microbiology*; D002648:Child; D006801:Humans; D010406:Penicillins / Q000627:therapeutic use; D010488:Polyarteritis Nodosa / Q000382:microbiology*; D012008:Recurrence; D012213:Rheumatic Fever / Q000382:microbiology / Q000473:pathology; D013290:Streptococcal Infections / Q000150:complications / Q000382:microbiology*; D013297:Streptococcus pyogenes; D013577:Syndrome
D010406:Penicillins