[Acute phase reaction in acute viral hepatitis].
We investigated serum concentrations of acute-phase-proteins (alpha 1-antitrypsin (alpha 1-AT), alpha 1-acid glycoprotein (alpha 1-sGP) and C-reactive protein (CRP)), and of complement components C3 and C4 during the course of acute hepatitis A and hepatitis B and correlated it to age and sex of the patients. Whereas a small increase of all three acute-phase-proteins was seen during acute hepatitis A, alpha 1-AT and CRP, but not alpha 1-aGP were found to be elevated during hepatitis B. A moderate elevation of C3 and C4 serum levels, more pronounced in hepatitis B than in hepatitis A, was seen followed by a slow return to normal. A systemic acute phase response seems not to be present during acute viral hepatitis in spite of the pronounced local inflammatory changes in liver tissue.
Gödl
I
I
Abteilung für Kinderinfektionskrankheiten und interne Kinderkrankheiten, Universität Wien.
Müller
C
C
Wolf
H
H
Eibl
M M
MM
D000209:Acute-Phase Proteins / Q000378:metabolism*; D000210:Acute-Phase Reaction / Q000175:diagnosis*; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006506:Hepatitis A / Q000097:blood / Q000175:diagnosis*; D006509:Hepatitis B / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D007249:Inflammation / Q000175:diagnosis*; D008111:Liver Function Tests; D008297:Male
D000209:Acute-Phase Proteins
Akut-Phase-Reaktion bei akuter viraler Hepatitis.