An audit of head and neck cancer treatment in a Regional Centre for Radiotherapy and Oncology.
All patients with head and neck cancer attending the Regional Centre for Radiotherapy and Oncology at Mount Vernon hospital during the 8-year period from 1 January 1980 to 31 December 1987 have been included in this review. The 545 patients presenting a new primary carcinoma without evidence for metastasis outside the locoregional area, who were treated primarily by radiotherapy are the subject of this present audit. The characteristics of the patients, of the tumours and of the treatment given have been related to outcome. Early tumours (T1 and T2 which were node-negative) showed a complete response (CR) rate of 94% whereas more advanced tumours (T1 and T2 with palpable lymph nodes) showed a CR of 59%. The probability of local tumour control at 5 years was 77% in those without nodes and 20% in those with nodes. For more advanced disease (T3 and T4 tumours), initial CR was 72% in node-negative disease and 32% when the nodes were positive. At 5 years, the probability of local tumour control fell to 37% and 0 respectively. CR, freedom from recurrence and survival were statistically significantly related to T stage, N stage and site of primary tumour. The results compare favourably with those reported by other institutions. The development of medical audit and its influence on treatment policy are considered.
Marie Curie Research Wing, Regional Centre for Radiotherapy and Oncology, Mount Vernon Hospital, Northwood, Middlesex, UK.
A
A
Hong
M I
MI
Saunders
S
S
Dische
E
E
Grosch
D
D
Fermont
R F
RF
Ashford
E J
EJ
Maher
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008485:Medical Audit; D009062:Mouth Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D010039:Otorhinolaryngologic Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D010166:Palliative Care; D011879:Radiotherapy Dosage; D015996:Survival Rate