Studies of three Amerindian populations using nuclear DNA polymorphisms.
Three Amerindian populations, two from Rondônia, Brazil (Karitiana and Rondônia Suruí), and one from Campeche, Mexico (Mayan), were typed for up to 30 nuclear restriction fragment length polymorphisms (RFLPs). Heterozygosities, both observed and expected, were compared with those of Europeans. Average heterozygosity is reduced among these Amerindians (relative to that of Europeans) by 7.0% (Mayan) to 27.1% (Karitiana). This amount of heterozygosity in the nuclear DNA is nevertheless high enough that it is unlikely that there was a severe or prolonged bottleneck.
Department of Human Genetics, Yale University School of Medicine, New Haven, CT 06510.
J R
JR
Kidd
F L
FL
Black
K M
KM
Weiss
I
I
Balazs
K K
KK
Kidd
D000483:Alleles; D001938:Brazil; D002874:Chromosome Mapping; D004247:DNA / Q000032:analysis*; D005787:Gene Frequency; D006579:Heterozygote; D006801:Humans; D007198:Indians, North American / Q000235:genetics*; D007199:Indians, South American / Q000235:genetics*; D008800:Mexico; D011110:Polymorphism, Genetic / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length; D011153:Population
D004247:DNA