[Activity of alanine aminopeptidase, beta-glucuronidase and N-acetyl-beta-d-glucosaminidase in urine of children with nephrotic syndrome].
Activity of alanine aminopeptidase (AAP), beta-glucuronidase, and N-acetyl-beta-D-glucosaminidase (NAG) in daily urine has been determined in 27 children with nephrotic syndrome, 14 children in remission, and 11 healthy children. It was found, that these enzymes activity is significantly increased in sick children in comparison with healthy ones. Similarly, the activity of AAP and NAG in daily urine is statistically significantly higher in children with remission, than that in healthy children. An assay of these enzymes in the urine may be used in the diagnosis of nephrotic syndrome and in the evaluation of its course.
Katedry i Zakładu Biochemii Farmaceutycznej.
T
T
Guszczyński
R
R
Bednorz
Z
Z
Morawska
D000118:Acetylglucosaminidase / Q000652:urine*; D000293:Adolescent; D000626:Aminopeptidases / Q000652:urine*; D018826:CD13 Antigens; D002648:Child; D002675:Child, Preschool; D005966:Glucuronidase / Q000652:urine*; D006801:Humans; D007223:Infant; D009404:Nephrotic Syndrome / Q000175:diagnosis / Q000201:enzymology*; D012016:Reference Values
D005966:Glucuronidase; D000118:Acetylglucosaminidase; D000626:Aminopeptidases; D018826:CD13 Antigens
Aktywność alanyloaminopeptydazy, beta-glukuronidazy i N-acetylo-beta-D-glukozaminidazy w moczu dzieci z zespołem nerczycowym.