[The use of highly polymorphic DNA systems in the demonstration of mixed chimerism following bone marrow transplantation].
The demonstration of restriction fragment length polymorphism (RFLP) of the highly polymorphic systems MS1, MS31, g3, and MS43 to detect mixed chimerism after bone marrow transplantation is discussed. Degree of heterozygosity, somatic stability and sensitivity are the parameters investigated to demonstrate the practicability of this method. Examples of mixed chimerism after bone marrow transplantation are shown.
Institut für Blutgruppenserologie, Universität Wien.
G F
GF
Fischer
I
I
Faé
P
P
Valent
W F
WF
Pickl
D016026:Bone Marrow Transplantation; D002678:Chimera; D004247:DNA / Q000235:genetics*; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D014184:Transplantation, Homologous
D004247:DNA
Der Einsatz hochpolymorpher Systeme der DNA zum Nachweis des gemischten Chimärismus nach Knochenmarkstransplantation.