Biogenesis of the bacterial pilus.
The assembly of surface structures in gram-negative bacteria requires specialized secretion and chaperone systems localized on both sides of the cytoplasmic membrane. Major advances have been made over the last year in understanding how these systems form part of a general strategy used by bacteria to cap and target interactive subunits imported into the periplasmic space to outer membrane uncapping and assembly sites.
Hultgren
S J
SJ
Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, Missouri 63110.
Normark
S
S
D001425:Bacterial Outer Membrane Proteins / Q000235:genetics; D001692:Biological Transport; D036781:Fimbriae Proteins; D010861:Fimbriae, Bacterial / Q000378:metabolism* / Q000648:ultrastructure; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial; D006090:Gram-Negative Bacteria / Q000235:genetics / Q000378:metabolism / Q000648:ultrastructure*; D007136:Immunoglobulins; D008954:Models, Biological; D009024:Morphogenesis / Q000235:genetics; D009876:Operon; D011487:Protein Conformation
D001425:Bacterial Outer Membrane Proteins; D007136:Immunoglobulins; D036781:Fimbriae Proteins