[A retroperitoneal embryonal carcinoma with a high HCG level].
A case of an embryonal carcinoma of the retroperitoneum in a 23-year-old male is reported. His serum, urinary HCG, serum alpha-fetoprotein, and LDH values were high. After combination chemotherapy, when the tumor markers decreased to within normal values, the retroperitoneal tumor was extirpated. Histologically, a small focus in the embryonal carcinoma and cartilage was seen in the fibrous scar tissue. Immunohistochemically, the cancer cells revealed negativity for HCG, alpha-fetoprotein, and the epithelial membrane antigen. However, with the recurrence of the tumor, his HCG and LDH values elevated. The patient died 8 months after the surgical extirpation of his retroperitoneal tumor.
Dept. of Pathology, Okayama City Hospital.
T
T
Murao
M
M
Sunami
H
H
Yoshioka
Y
Y
Saito
T
T
Fujita
D000328:Adult; D014408:Biomarkers, Tumor / Q000378:metabolism; D006063:Chorionic Gonadotropin / Q000097:blood / Q000378:metabolism* / Q000652:urine; D006801:Humans; D008297:Male; D012186:Retroperitoneal Neoplasms / Q000378:metabolism* / Q000473:pathology; D013724:Teratoma / Q000378:metabolism* / Q000473:pathology; D000509:alpha-Fetoproteins / Q000378:metabolism
D014408:Biomarkers, Tumor; D006063:Chorionic Gonadotropin; D000509:alpha-Fetoproteins