Early intraocular pressure response to laser trabeculoplasty 180 degrees without apraclonidine versus 360 degrees with apraclonidine.
Early postoperative intraocular pressure elevation (IOP) is less common after 180-degree than after 360-degree argon laser trabeculoplasty (ALT). We retrospectively reviewed the charts of 38 patients treated with 360-degree ALT and perioperative 1% apraclonidine, and those of 39 patients treated with 180-degree ALT without apraclonidine, to determine whether apraclonidine offset the increased risk of transient pressure elevation following 360-degree treatment, as compared with that after 180-degree therapy. The average IOP change and the frequency of pressure elevations at 1 hour, 1 day, and 1 month postoperatively were similar in the two groups. With respect to early postoperative IOP elevation, 360-degree ALT with perioperative apraclonidine appears to be as safe as 180-degree ALT without apraclonidine.
Duke University Eye Center, Durham, NC 27710.
B E
BE
Allf
M B
MB
Shields
D000316:Adrenergic alpha-Agonists / Q000627:therapeutic use*; D000368:Aged; D003000:Clonidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D005901:Glaucoma / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D053685:Laser Therapy; D008297:Male; D011183:Postoperative Complications / Q000188:drug therapy; D012189:Retrospective Studies; D014130:Trabeculectomy; D016896:Treatment Outcome
D000316:Adrenergic alpha-Agonists; C016986:apraclonidine; D003000:Clonidine