Lower-limb vasospasm and renal failure during postoperative thromboprophylaxis. Case report.
In a 73-year-old woman with trimalleolar fracture, secondary acute ischemia of the limb and renal failure developed in association with heparin-dihydroergotamine thromboprophylaxis. Earlier cases of thromboprophylaxis-related angiospasm are briefly reviewed. The condition is infrequent, but trauma of extremities and shock are risk factors. Renal failure is rare.
Department of Orthopedic Surgery, Malmö General Hospital, Lund University, Sweden.
E
E
Mattsson
A
A
Ohlin
B
B
Balkfors
H O
HO
Fredin
P
P
Nilsson
D
D
Bergqvist
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000368:Aged; D000792:Angiography; D004087:Dihydroergotamine / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006493:Heparin / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007511:Ischemia / Q000139:chemically induced* / Q000000981:diagnostic imaging; D007866:Leg / Q000098:blood supply*; D011183:Postoperative Complications / Q000517:prevention & control*; D013035:Spasm / Q000139:chemically induced; D013924:Thrombophlebitis / Q000517:prevention & control*; D014661:Vasoconstriction / Q000187:drug effects
D004087:Dihydroergotamine; D006493:Heparin