Radiation resistance of clinical Acinetobacter spp.: a need for concern?
As part of an epidemiological investigation of hospital infections caused by Acinetobacter spp. the radiation resistance of 15 clinical isolates and four reference strains was assessed. The radiation resistance (in D-6 values, viz. the dose necessary for reducing the initial number of colony forming units by a factor of 10(6)) was, in general, higher in the isolates of A. radioresistens than in the isolates of the A. calcoaceticus-A. baumannii complex and of A. lwoffi. However, the least resistant isolates of A. radioresistens had a D-6 value equal to or lower than the most resistant isolates of the other groups. The lowest D-6 values found were for two of the reference strains. The highest D-6 value was 35 kGy. Three isolates of A. johnsonii could not survive long enough in a dried preparation to make an assessment of the D-6 values possible. The radiation resistance of the 15 clinical isolates in the present study was higher than the resistance found in a study of similar isolates in 1970.
Christensen
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Control Department, Statens Seruminstitut, Copenhagen, Denmark.
Gerner-Smidt
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Kristensen
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D000150:Acinetobacter / Q000528:radiation effects*; D003428:Cross Infection / Q000382:microbiology; D004307:Dose-Response Relationship, Radiation; D006801:Humans