Modulation of metabolism and anti-HIV-1 activity of purine 2',3'-dideoxynucleosides by IMP dehydrogenase inhibitors.
Bondoc
L L
LL
Division of Biochemical and Clinical Pharmacology, St. Jude Children's Research Hospital, Memphis, Tennessee 38101.
Robbins
B L
BL
Ahluwalia
G S
GS
Mitsuya
H
H
Johns
D G
DG
Fridland
A
A
D000998:Antiviral Agents / Q000494:pharmacology*; D002460:Cell Line; D016048:Dideoxyadenosine / Q000494:pharmacology*; D015224:Dideoxynucleosides / Q000494:pharmacology*; D004347:Drug Interactions; D015497:HIV-1 / Q000187:drug effects* / Q000378:metabolism; D006801:Humans; D007168:IMP Dehydrogenase / Q000037:antagonists & inhibitors*; D012254:Ribavirin / Q000494:pharmacology*; D013601:T-Lymphocytes
D000998:Antiviral Agents; D015224:Dideoxynucleosides; C057503:carbovir; D012254:Ribavirin; D016048:Dideoxyadenosine; C050220:2',3'-dideoxyguanosine; D007168:IMP Dehydrogenase