Peptide T a new treatment for psoriasis? A study of nine patients.
Nine patients with recalcitrant and long-standing psoriasis were treated over a period of 28 days with 2 mg Peptide T iv, once daily (22-34 micrograms/kg bodyweight). Eight of them showed an improvement of less than 50% by day 28 and one deteriorated. The patients were evaluated for a further 3 months when no topical or systemic treatment was given. Five patients recovered by more than 50%, during the months following termination of the therapy. Two patterns of healing were noted: firstly, a steady clearance beginning immediately with the Peptide T infusions; secondly, a clearance pattern preceded by deterioration. No serious side effects were noted.
Department of Dermatology, Huddinge Hospital, Sweden.
J A
JA
Marcusson
T
T
Talme
L
L
Wetterberg
O
O
Johansson
D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D015717:Peptide T / Q000009:adverse effects / Q000627:therapeutic use*; D011565:Psoriasis / Q000188:drug therapy* / Q000473:pathology
D015717:Peptide T