Psychoactive drug use in an institution for intellectually handicapped persons.
OBJECTIVE
To study the use of psychoactive drugs for the treatment of long-stay developmentally disabled individuals in an institution in New South Wales.


METHODS
Three wards dedicated to the long-term care of developmentally disabled individuals situated on the premises of a large psychiatric hospital.


METHODS
All residents (n = 53) of these wards in August 1989.


METHODS
All subjects were examined by the author. Charts and medication records were extensively reviewed. Mental retardation was classified by DSM-III-R criteria. Categorisation of problem behaviour was done with the assistance of nurses, who also supplied information on behavioural problems and functional level and completed checklists of self-injurious and stereotypic behaviour. A standardised neurological examination was performed and scales for abnormal involuntary movements completed.


RESULTS
The most commonly used drugs were the neuroleptics, with 60.4% of subjects currently receiving one or more neuroleptic drug at relatively large doses. The use of these drugs was not associated with current or past psychiatric illness, but was more closely related with the severity of problem behaviour. Thirty-four per cent of the subjects receiving neuroleptics had dyskinetic movements suggestive of tardive dyskinesia, and 30% had mild tremor. Antidepressant, anxiolytic and sedative drugs were used less commonly. The management of epilepsy was considered to be suboptimal.


CONCLUSIONS
Even though studies over the last two decades have consistently highlighted the problem of overmedication of intellectually handicapped individuals in institutions, the problem does not seem to have been redressed in at least some institutions.
Neuropsychiatric Institute, Prince Henry Hospital, Little Bay, NSW.
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Sachdev
D000293:Adolescent; D000328:Adult; D000368:Aged; D000927:Anticonvulsants / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001519:Behavior / Q000187:drug effects; D004409:Dyskinesia, Drug-Induced / Q000209:etiology; D004827:Epilepsy / Q000188:drug therapy; D005260:Female; D006801:Humans; D007326:Institutionalization; D008607:Intellectual Disability / Q000188:drug therapy*; D008134:Long-Term Care; D008297:Male; D008875:Middle Aged; D011618:Psychotic Disorders / Q000188:drug therapy*; D011619:Psychotropic Drugs / Q000627:therapeutic use*; D012189:Retrospective Studies; D013239:Stereotyped Behavior / Q000187:drug effects
D000927:Anticonvulsants; D014150:Antipsychotic Agents; D011619:Psychotropic Drugs