Human polymorphic probe pE1.8 detects SacI polymorphism in the ribonucleotide reductase M1 subunit gene.
A new human polymorphic probe to the ribonucleotide reductase M1 subunit gene is described. The location of this gene at chromosome 11p15 makes it a useful marker for studying DNA rearrangements in embryonal tumours.
Byrne
J
J
Department of Pathology, University of Queensland Medical School, Herston, Australia.
Smith
P
P
D002880:Chromosomes, Human, Pair 11; D015342:DNA Probes; D015252:Deoxyribonucleases, Type II Site-Specific / Q000378:metabolism; D005787:Gene Frequency; D006801:Humans; D012150:Polymorphism, Restriction Fragment Length; D012264:Ribonucleotide Reductases / Q000235:genetics*
D015342:DNA Probes; D012264:Ribonucleotide Reductases; C024408:endodeoxyribonuclease SacI; D015252:Deoxyribonucleases, Type II Site-Specific