Maternal and perinatal complications in neurofibromatosis during pregnancy.
A total of ten patients with lesions of neurofibromatosis during pregnancy were followed up for pregnancy complications. Seven cases (70%) had hypertensive disorders of pregnancy; four had severe PET (pre-eclamptic toxemia) including one case of eclampsia, one had mild PET and the other two had only mild gestational hypertension. A total of 60% had preterm labor and in none of these did the baby survive; thus perinatal mortality was 600/1000. Mean gestation was 33.0 weeks and mean birthweight was only 1.924 kg. Thus, neurofibromatosis during pregnancy is associated with poor obstetrical outcome and requires greater care.
Sharma
J B
JB
Department of Obstetrics and Gynaecology-II, Medical College and Hospital, Rohtak, Haryana, India.
Gulati
N
N
Malik
S
S
D000328:Adult; D001724:Birth Weight; D005260:Female; D005313:Fetal Death / Q000209:etiology*; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007231:Infant, Newborn; D009456:Neurofibromatosis 1 / Q000150:complications*; D007752:Obstetric Labor, Premature / Q000209:etiology; D011225:Pre-Eclampsia / Q000150:complications / Q000209:etiology*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000209:etiology*; D011252:Pregnancy Complications, Neoplastic