Somatostatin concentrations in the pancreatic-intestinal tissues of the sea lamprey, Petromyzon marinus L., at various periods of its life cycle.
1. Somatostatin concentrations were measured in homogenates of the pancreas-intestinal tissues from each period of the life cycle of Petromyzon marinus using radioimmunoassay. 2. Levels were very low in larva (4.0 pg/mg wet weight) and in the first three stages of metamorphosis, but increased from stage 4 onwards and reached a high in upstream-migrating adults (210.0 ng/mg). 3. These data correlate well with our previous morphological and immunohistochemical observations on the morphogenesis of somatostatin-containing D-cells during the life cycle and indicate that the increased concentration of hormone accompanies the development of the endocrine pancreas in lampreys.
Elliott
W M
WM
Department of Zoology, University of Toronto, Ontario, Canada.
Youson
J H
JH
D000818:Animals; D005260:Female; D007413:Intestinal Mucosa / Q000378:metabolism*; D007798:Lampreys / Q000254:growth & development* / Q000378:metabolism; D008297:Male; D010179:Pancreas / Q000378:metabolism*; D011863:Radioimmunoassay; D013004:Somatostatin / Q000378:metabolism*
D013004:Somatostatin