[The surface antigens of Rickettsia prowazekii studied with monoclonal antibodies].
R. prowazekii antigens have been tested with the use of monoclonal antibodies (McAb) to different epitopes of the microorganism. As revealed in these tests, McAb B4/4 and A-3/D, active against species-specific thermolabile antigen, interact with protein having a molecular weight of 90-120 KD. McAb C5/2, active against thermostable group antigen common with that of Rickettsia typhi, interact with LPS-like antigen having a molecular weight of 30 KD. Ultrastructural immunochemical studies have revealed that both R. prowazekii antigens are located on surface structures of rickettsiae, such as the microcapsule and cell wall.
Iu A
IuA
Nedialkov
S V
SV
Spitsyn
E I
EI
Drobyshevskaia
V V
VV
Gosteva
N V
NV
Klitsunova
N S
NS
Smirnova
I V
IV
Tarasevich
V G
VG
Nesterenko
D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis; D003381:Coxiella / Q000276:immunology; D000939:Epitopes / Q000276:immunology; D007158:Immunologic Techniques; D008854:Microscopy, Electron; D008970:Molecular Weight; D012283:Rickettsia prowazekii / Q000276:immunology* / Q000648:ultrastructure; D012286:Rickettsia typhi / Q000276:immunology; D013045:Species Specificity
D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial; D000954:Antigens, Surface; D000939:Epitopes
Izuchenie poverkhnostnykh antigenov Rickettsia prowazekii pri pomoshchi monoklonal'nykh antitel.