Ultrasonographic diagnosis of a large placental intervillous thrombosis associated with elevated maternal serum alpha-fetoprotein level.
A placental lesion associated with elevated maternal serum alpha-fetoprotein level and a positive Kleihauer-Betke test is reported. Serial ultrasonograms showed a progressive increase in the echogenicity of the lesion that corresponded to a large intervillous thrombosis after delivery. This case illustrates the importance of detailed ultrasonographic and pathologic placental investigations in pregnancies with unexplained elevated levels of alpha-fetoprotein.
Department of Obstetrics and Gynecology, King's College Hospital School of Medicine and Dentistry, University of London, England.
E
E
Jauniaux
D
D
Gibb
G
G
Moscoso
S
S
Campbell
D000328:Adult; D002824:Chorionic Villi; D005260:Female; D006801:Humans; D010922:Placenta Diseases / Q000097:blood / Q000000981:diagnostic imaging*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood / Q000000981:diagnostic imaging*; D013927:Thrombosis / Q000097:blood / Q000000981:diagnostic imaging*; D016216:Ultrasonography, Prenatal; D000509:alpha-Fetoproteins / Q000378:metabolism*
D000509:alpha-Fetoproteins