[Anaphylactic shock after sucking on a throat lozenge].
A few minutes after sucking a lozenge for a sore throat a 68-year-old man developed an anaphylactic shock. At a heart rate of 110/min there was no palpable blood pressure. A red confluent exanthem, predominantly of the trunk, was noted. After brief intensive-care treatment the patient was completely well again and diagnostic tests for allergy were performed. The prick test for the 14 individual ingredients of the throat lozenge produced massive reddening and urticaria on the test arm with carbowax, a polyethylene glycol which serves as a vehicle in the remedy and does not have to be listed. Later there were an urge to cough and urticaria all over the trunk. There was no systemic reaction. Neither specific IgE antibodies nor any complement-consuming reaction could be demonstrated. Thus the precipitating mechanism remains unexplained.
Karl-Hansen-Klinik, Bad Lippspringe.
C
C
Hesselbach
W
W
Böhning
R
R
Wettengel
D010129:4-Aminobenzoic Acid / Q000009:adverse effects; D000368:Aged; D000707:Anaphylaxis / Q000139:chemically induced* / Q000175:diagnosis; D001592:Benzyl Alcohols / Q000009:adverse effects*; D001593:Benzyl Compounds / Q000009:adverse effects*; D002594:Cetylpyridinium / Q000009:adverse effects*; D003937:Diagnosis, Differential; D004338:Drug Combinations / Q000009:adverse effects; D006096:Gramicidin / Q000009:adverse effects*; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D008297:Male; D010592:Pharmaceutic Aids / Q000009:adverse effects; D010614:Pharynx; D011726:Pyridinium Compounds / Q000009:adverse effects*; D012882:Skin Tests; D013607:Tablets; D062366:para-Aminobenzoates
D001592:Benzyl Alcohols; D001593:Benzyl Compounds; D004338:Drug Combinations; D010592:Pharmaceutic Aids; D011726:Pyridinium Compounds; D013607:Tablets; D062366:para-Aminobenzoates; D006096:Gramicidin; D007073:Immunoglobulin E; C009812:imposit; D002594:Cetylpyridinium; D010129:4-Aminobenzoic Acid
Anaphylaktischer Schock nach Einnahme einer Lutschtablette.