The role of chemoprophylaxis in the prevention of airborne infection by fungal pathogens.
The main approach to prevention of infection following airborne transmission of pathogenic fungi such as Aspergillus species has been environmental. However, there are a number of potentially effective methods of prophylaxis using antifungal drugs. Those described previously include itraconazole or amphotericin B given by the intranasal or intrapulmonary route after nebulization. Another possibility for investigation in the future is enilconazole which is highly active against aspergilli after inhalation in animals and which has been used in the treatment of aspergillosis in poultry.
Hay
R J
RJ
Department of Dermatology, Guys Hospital, London, UK.
D000391:Air Microbiology; D000935:Antifungal Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D003428:Cross Infection / Q000188:drug therapy* / Q000453:epidemiology / Q000517:prevention & control; D006801:Humans; D009181:Mycoses / Q000188:drug therapy* / Q000453:epidemiology / Q000517:prevention & control
D000935:Antifungal Agents