Primary structure of cAMP-gated channel from bovine olfactory epithelium.
The complete amino-acid sequence of the bovine olfactory epithelium adenosine 3',5'-cyclic monophosphate (cAMP)-gated channel has been determined by cloning and sequencing its cDNA. It exhibits a high degree of sequence homology with the cGMP-gated channel of rod photoreceptors, suggesting that cyclic nucleotide-gated channels fall into a new family of genetically related proteins.
Institut für Biologische Informationsverarbeitung, Forschungszentrum Jülich, FRG.
J
J
Ludwig
T
T
Margalit
E
E
Eismann
D
D
Lancet
U B
UB
Kaupp
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002417:Cattle; D003001:Cloning, Molecular; D000242:Cyclic AMP / Q000502:physiology*; D006152:Cyclic GMP / Q000502:physiology; D015640:Ion Channel Gating; D007473:Ion Channels / Q000737:chemistry* / Q000235:genetics*; D008969:Molecular Sequence Data; D009474:Neurons / Q000737:chemistry*; D009831:Olfactory Mucosa / Q000737:chemistry*; D011061:Poly A / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics; D012689:Sequence Homology, Nucleic Acid
D007473:Ion Channels; D012333:RNA, Messenger; D011061:Poly A; D000242:Cyclic AMP; D006152:Cyclic GMP