Polypeptide growth factors in the regulation of human tumor cell proliferation.
The capacity of growth factors to activate receptors through autocrine and paracrine pathways continues to be a major focus of cancer biology research. This review of growth factors for solid tumor cells complements our summary of hematopoietic growth factors.
Memorial Sloan-Kettering Cancer Center, New York, New York.
R
R
Kumar
J
J
Mendelsohn
D066258:Amphiregulin; D002454:Cell Differentiation / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D066255:EGF Family of Proteins; D004815:Epidermal Growth Factor / Q000502:physiology; D066246:ErbB Receptors / Q000187:drug effects / Q000502:physiology; D006023:Glycoproteins / Q000494:pharmacology; D006133:Growth Substances / Q000494:pharmacology / Q000502:physiology*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins; D009369:Neoplasms / Q000235:genetics / Q000473:pathology*; D010982:Platelet-Derived Growth Factor / Q000494:pharmacology; D011518:Proto-Oncogene Proteins / Q000235:genetics / Q000502:physiology; D018719:Erb-b2 Receptor Tyrosine Kinases; D011956:Receptors, Cell Surface / Q000187:drug effects / Q000502:physiology; D017479:Receptors, Platelet-Derived Growth Factor; D012689:Sequence Homology, Nucleic Acid; D016211:Transforming Growth Factor alpha / Q000494:pharmacology; D016212:Transforming Growth Factor beta / Q000494:pharmacology; D014407:Tumor Cells, Cultured / Q000187:drug effects
D066258:Amphiregulin; D066255:EGF Family of Proteins; D004815:Epidermal Growth Factor; D066246:ErbB Receptors; D006023:Glycoproteins; D006133:Growth Substances; D036341:Intercellular Signaling Peptides and Proteins; D010982:Platelet-Derived Growth Factor; D011518:Proto-Oncogene Proteins; D018719:Erb-b2 Receptor Tyrosine Kinases; D011956:Receptors, Cell Surface; D017479:Receptors, Platelet-Derived Growth Factor; D016211:Transforming Growth Factor alpha; D016212:Transforming Growth Factor beta; C587848:AREG protein, human