Myofibroblastoma of the tongue. An immunohistochemical, ultrastructural, and flow cytometric study.
A case of myofibroblastoma arising in the tongue of a 77-year-old man is described. The patient presented with a submucosal tongue mass without other associated symptoms. The tumor was 2 cm in diameter, well circumscribed, and composed of uniform spindle cells arranged in fascicles. Electron microscopic examination and immunohistochemistry demonstrated a myofibroblastic origin for the tumor cells. DNA flow cytometric analysis showed a diploid DNA content of this tumor. To the authors' knowledge, this is the first report of myofibroblastoma occurring in the tongue.
Department of Pathology, University of Texas, M. D. Anderson Cancer Center, Houston 77030.
A A
AA
Sahin
J Y
JY
Ro
N G
NG
Ordoñez
M A
MA
Luna
A K
AK
el-Naggar
H
H
Goepfert
A G
AG
Ayala
D000199:Actins / Q000378:metabolism; D000368:Aged; D003094:Collagen / Q000378:metabolism; D003893:Desmin / Q000378:metabolism; D005434:Flow Cytometry; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000378:metabolism; D007889:Leiomyoma / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D009418:S100 Proteins / Q000378:metabolism; D014062:Tongue Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure
D000199:Actins; D003893:Desmin; D009418:S100 Proteins; D007633:Keratins; D003094:Collagen