Synthesis and biological evaluation of some piperazine derivatives of isothiazolo[5,4-b]pyridin-3-one and its 1,1-dioxide.
Malinka
W
W
Department of Chemistry of Drug, School of Medicine, Wrocław, Poland.
D000700:Analgesics / Q000138:chemical synthesis / Q000494:pharmacology; D000818:Animals; D014150:Antipsychotic Agents / Q000138:chemical synthesis / Q000494:pharmacology; D002491:Central Nervous System Agents / Q000138:chemical synthesis* / Q000494:pharmacology*; D007928:Lethal Dose 50; D051379:Mice; D010879:Piperazines / Q000138:chemical synthesis* / Q000494:pharmacology; D011744:Pyrimidinones / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats
D000700:Analgesics; D014150:Antipsychotic Agents; D002491:Central Nervous System Agents; D010879:Piperazines; D011744:Pyrimidinones