Ketamine, midazolam and vecuronium infusion. Anaesthesia for Down's syndrome and congenital heart disease.
A ketamine, midazolam and vecuronium infusion was used for total intravenous anesthesia in a patient with Down's syndrome, a ventricular septal defect and pulmonary hypertension. A mixture of ketamine 200 mg, midazolam 5 mg and vecuronium 12 mg in 50 ml of normal saline was infused at 0.5 ml/kg/hour. This simple technique and ventilation with 100% oxygen maintained tissue oxygenation and cardiovascular stability.
Department of Anaesthesia and Intensive Care, Royal Newcastle Hospital, NSW, Australia.
D P
DP
Riley
L J
LJ
McBride
D000328:Adult; D000771:Anesthesia, Intravenous; D002387:Cataract Extraction; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006345:Heart Septal Defects, Ventricular / Q000150:complications*; D006801:Humans; D007262:Infusions, Intravenous; D007649:Ketamine; D008874:Midazolam / Q000008:administration & dosage; D014673:Vecuronium Bromide / Q000008:administration & dosage
D007649:Ketamine; D014673:Vecuronium Bromide; D008874:Midazolam