"Anemone" cell (villiform) tumor of the brain.
At age 31, the patient developed hydrocephalus secondary to a brain lesion that had been present for 12 years. A ventriculoperitoneal shunt was performed, but a stereotactic biopsy did not establish a definitive diagnosis at that time. At age 34 the patient experienced spontaneous intratumoral and ventricular hemorrhage, which prompted radical surgical resection of the lesion. Histologic and immunocytochemical findings established a diagnosis of ependymoma; review of the ultrastructure of the tumor from the biopsy performed when the patient was 31 years old revealed the characteristics of an "anemone" cell neoplasm.
Deck
J H
JH
Department of Pathology, Toronto General Hospital, Ontario, Canada.
Ramjohn
S
S
Dardick
I
I
D000328:Adult; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology*; D002467:Cell Nucleus / Q000648:ultrastructure; D002543:Cerebral Hemorrhage / Q000209:etiology; D003593:Cytoplasm / Q000648:ultrastructure; D003937:Diagnosis, Differential; D004806:Ependymoma / Q000150:complications / Q000473:pathology*; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D008297:Male; D008854:Microscopy, Electron; D009418:S100 Proteins / Q000032:analysis; D014746:Vimentin / Q000032:analysis
D005904:Glial Fibrillary Acidic Protein; D009418:S100 Proteins; D014746:Vimentin; D007633:Keratins