Coadministration of flecainide acetate and sotalol during pregnancy: lack of teratogenic effects, passage across the placenta, and excretion in human breast milk.
Wagner
X
X
ADRs Monitoring Department, 3M Santé Laboratories, Malakoff, France.
Jouglard
J
J
Moulin
M
M
Miller
A M
AM
Petitjean
J
J
Pisapia
A
A
D000328:Adult; D005117:Cardiac Complexes, Premature / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D005424:Flecainide / Q000493:pharmacokinetics / Q000627:therapeutic use* / Q000633:toxicity; D006801:Humans; D008431:Maternal-Fetal Exchange / Q000187:drug effects; D008895:Milk, Human / Q000032:analysis; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy*; D011256:Pregnancy Outcome; D013015:Sotalol / Q000493:pharmacokinetics / Q000627:therapeutic use*; D013610:Tachycardia / Q000188:drug therapy*
D013015:Sotalol; D005424:Flecainide