Arduan muscle relaxation prolonged with norcuron.
Norcuron injection has been applied for the prolongation of the duration of muscle relaxing action of Arduan in 104 patients. The patients underwent major surgery and 1/5 of them were of advanced age. Neuromuscular blockade could be prolonged for the required duration of operation with lower doses of Norcuron (2 mg, 1 mg) than the currently used ones. For avoiding eventual cumulation or synergism the repetition of lower doses to meet the requirements seems to be the most advantageous method.
Department of Anaesthesiology, Municipal János Hospital-Outpatient Clinic, Budapest.
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D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015113:Androstane-3,17-diol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D000758:Anesthesia / Q000379:methods*; D004359:Drug Therapy, Combination; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008875:Middle Aged; D009466:Neuromuscular Blocking Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D017300:Pipecuronium; D010879:Piperazines / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D014673:Vecuronium Bromide / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*
D009466:Neuromuscular Blocking Agents; D010879:Piperazines; D017300:Pipecuronium; D015113:Androstane-3,17-diol; D014673:Vecuronium Bromide