Genomic clone OS-2 (D10S20) detects different restriction fragment length polymorphisms in Caucasians and Orientals for both HindIII and TaqI.
Restriction fragment length polymorphisms (RFLPs) for the anonymous DNA probe OS-2 were studied in a Caucasian population. In a sample of 15 two- and three-generation families and 31 unrelated individuals, the restriction endonuclease TaqI revealed an RFLP not seen in a Japanese sample. A similar situation has been observed for this probe with the restriction endonuclease HindIII.
Department of Psychiatry, Washington University School of Medicine, St. Louis, Mo.
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D044466:Asian People / Q000235:genetics; D002879:Chromosomes, Human, Pair 10 / Q000648:ultrastructure*; D015342:DNA Probes; D015252:Deoxyribonucleases, Type II Site-Specific; D005260:Female; D006801:Humans; D008297:Male; D010375:Pedigree; D012150:Polymorphism, Restriction Fragment Length; D044465:White People / Q000235:genetics
D015342:DNA Probes; D015252:Deoxyribonucleases, Type II Site-Specific; C027046:TCGA-specific type II deoxyribonucleases