Coexpression of intermediate-sized filaments in sialadenoma papilliferum and other salivary gland neoplasms.
The neoplastic cells present in a sialadenoma pappiliferum were found by immunoperoxidase method and immunofluorescent staining technique to co-express 3 different types of intermediate-sized filaments (IFs) defined by monoclonal antibodies to cytokeratin, vimentin and desmin. When other salivary gland tumors such as 18 pleomorphic adenomas, 15 adenolymphomas, 2 oxyphilic adenomas, 7 mucoepidermoid tumors, 5 acinic cell tumors, 8 adenoid cystic carcinomas and 6 adenocarcinomas were examined immunohistochemically for the expression of IFs, no tumors with all 3 types of IFs observed in sialadenoma papilliferum were found.
Nakahata
A
A
Department of Oral Pathology, Tokushima University School of Dentistry, Japan.
Deguchi
H
H
Yanagawa
T
T
Yoshida
H
H
Sato
M
M
Hayashi
Y
Y
D000230:Adenocarcinoma / Q000737:chemistry / Q000648:ultrastructure; D000235:Adenolymphoma / Q000737:chemistry / Q000648:ultrastructure; D008949:Adenoma, Pleomorphic / Q000737:chemistry / Q000648:ultrastructure; D002277:Carcinoma / Q000737:chemistry / Q000648:ultrastructure; D003528:Carcinoma, Adenoid Cystic / Q000737:chemistry / Q000648:ultrastructure; D003893:Desmin / Q000032:analysis; D005455:Fluorescent Antibody Technique; D006801:Humans; D007124:Immunoenzyme Techniques; D007382:Intermediate Filaments / Q000737:chemistry / Q000648:ultrastructure*; D007633:Keratins / Q000032:analysis; D010212:Papilloma / Q000737:chemistry / Q000648:ultrastructure; D012468:Salivary Gland Neoplasms / Q000737:chemistry / Q000648:ultrastructure*; D014746:Vimentin / Q000032:analysis
D003893:Desmin; D014746:Vimentin; D007633:Keratins