Heterogeneity of lymphocytes from aqueous humor of patients with uveitis.
T lymphocyte subsets from inflammatory aqueous humor (n = 34) have shown one of three different patterns: group 1 = lower CD4+/CD8+ ratio in aqueous as compared to peripheral blood (0.43 +/- 0.25 vs. 1.96 +/- 0.82; n = 9); group 2 = similar CD4+/CD8+ ratio in aqueous and peripheral blood (1.76 +/- 0.60 vs. 1.60 +/- 0.62; n = 22); and group 3 = higher CD4+/CD8+ ratio in aqueous as compared to peripheral blood (7.53 +/- 0.47 vs. 2.13 +/- 0.55; n = 3). DR+ T lymphocytes were significantly higher, and natural killer cells significantly lower, in inflammatory aqueous as compared to peripheral blood.
Secchi
A G
AG
Institute of Ophthalmology, University of Padova School of Medicine, Italy.
Fregona
I A
IA
Tognon
M S
MS
Marcon
G B
GB
D001082:Aqueous Humor / Q000166:cytology*; D015496:CD4-Positive T-Lymphocytes; D006801:Humans; D007694:Killer Cells, Natural; D007958:Leukocyte Count; D016176:T-Lymphocyte Subsets; D050378:T-Lymphocytes, Regulatory; D014605:Uveitis / Q000097:blood / Q000473:pathology*