Epitope-specific regulation and the literature.
The antibody response to a hapten conjugated to a protein can, in a number of situations, be suppressed by prior immunization with the carrier protein alone. The study of this finding appears to have been handicapped by previous literature on the subject having been consistently misquoted. It is to be hoped that recognition of this will allow a better understanding of the limitations to such suppression, and hence the mechanism by which it may act.
Department of Gene Structure and Expression, National Institute for Medical Research, London, UK.
J I
JI
Elliott
D000818:Animals; D002352:Carrier Proteins / Q000276:immunology; D000939:Epitopes / Q000276:immunology*; D006241:Haptens / Q000276:immunology; D007165:Immunosuppression Therapy; D010506:Periodicals as Topic
D002352:Carrier Proteins; D000939:Epitopes; D006241:Haptens