[Evaluation of fetal lung maturity with the measurement of enzymatic activities in amniotic fluid: comparison of three ratios].
Measurement, in amniotic fluid, of gamma-glutamyl-transferase (GGT) alkaline phosphatase and of thermostable and thermolabile (TLAP) isoenzyme allows to anticipate the unexpected risk of hyaline membrane disease. ROC method adapted to three ratio of these enzymatic activities shows that TLAP/GGT is the most performant at the level of 0.9 with a sensitivity of 96% and a specificity of 60%.
Forzy
G
G
Département de Gynécologie-Obstétrique, Centre Hospitalier Saint-Philbert, Faculté Libre de Médecine de Lille, Lomme.
Houze de l'aulnoit
D
D
Brabant
G
G
Ellart
D
D
Dhondt
J L
JL
Delcroix
M
M
D000469:Alkaline Phosphatase / Q000378:metabolism*; D000653:Amniotic Fluid / Q000201:enzymology*; D005260:Female; D005325:Fetal Organ Maturity; D006801:Humans; D008168:Lung / Q000196:embryology*; D011247:Pregnancy; D005723:gamma-Glutamyltransferase / Q000378:metabolism*
D005723:gamma-Glutamyltransferase; D000469:Alkaline Phosphatase
Evaluation de la maturité pulmonaire foetale par la mesure d'activités enzymatiques du liquide amniotique: comparaison de trois rapports.