Comparison of two experimental binary ethylenimine (BEI) inactivated Newcastle disease oil-emulsion vaccines.
Mesogenic R2B Mukteswar strain of Newscastle disease virus derived from tissue culture and allantoic fluid was inactivated with binary ethylenimine (BEI). Oil-emulsion vaccines using both substrates were prepared and tested for their potency in chickens. The vaccines elicited a good serological response as assessed by haemagglutination inhibition (HI) test and had an adequate potency as evaluated by challenge test.
Reddy
G S
GS
Indian Immunologicals, Hyderabad.
Srinivasan
V A
VA
D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis; D001388:Aziridines / Q000494:pharmacology*; D002478:Cells, Cultured; D002645:Chickens; D006224:Cricetinae; D004655:Emulsions; D009522:Newcastle disease virus / Q000187:drug effects* / Q000254:growth & development; D009821:Oils; D015164:Vaccines, Inactivated; D014765:Viral Vaccines; D014775:Virus Activation / Q000187:drug effects* / Q000276:immunology
D000914:Antibodies, Viral; D001388:Aziridines; D004655:Emulsions; D009821:Oils; D015164:Vaccines, Inactivated; D014765:Viral Vaccines; C033132:aziridine