Enkephalin and serotonin innervation of somatostatin-immunoreactive medullary reticular formation neurones.
Somatostatin cells in the rat medullary reticular formation (Md) have been studied using peroxidase-antiperoxidase immunocytochemistry. Large fusiform and multipolar somatostatin immunoreactive cells were observed in the ventral subnucleus (MdV) running in a band close to the border with the dorsal subnucleus (MdD). In the same region somatostatin-, serotonin- and enkephalin-immunoreactive fibres occur and double staining revealed that these all contact the somatostatin-immunoreactive cells, with enkephalin making a particularly dense innervation.
Department of Physiology, UMDS St. Thomas's Hospital Medical School Campus, London, U.K.
J J
JJ
López Costa
S
S
Marter
T J
TJ
Görcs
J P
JP
Saavedra
J V
JV
Priestley
D000818:Animals; D004745:Enkephalins / Q000032:analysis*; D007124:Immunoenzyme Techniques; D008297:Male; D008526:Medulla Oblongata / Q000166:cytology / Q000502:physiology*; D009474:Neurons / Q000166:cytology / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D012154:Reticular Formation / Q000166:cytology / Q000502:physiology*; D012701:Serotonin / Q000032:analysis*; D013004:Somatostatin / Q000032:analysis*
D004745:Enkephalins; D012701:Serotonin; D013004:Somatostatin