Expression of dystrophin mRNA and the protein in the developing rat heart.
We examined the expression of dystrophin mRNA and the protein in the developing rat heart with polymerase chain reaction, immunoblotting and immunohistochemical analyses. Dystrophin mRNA was detectable on and after the 10th embryonic day, while the protein became detectable during the perinatal period.
National Institute of Neuroscience NCNP, Tokyo, Japan.
H
H
Tanaka
E
E
Ozawa
D000375:Aging; D000818:Animals; D001483:Base Sequence; D016189:Dystrophin / Q000096:biosynthesis / Q000235:genetics* / Q000302:isolation & purification; D005314:Embryonic and Fetal Development; D006321:Heart / Q000196:embryology / Q000254:growth & development*; D008969:Molecular Sequence Data; D008970:Molecular Weight; D015345:Oligonucleotide Probes; D016133:Polymerase Chain Reaction; D012313:RNA / Q000235:genetics / Q000302:isolation & purification; D012333:RNA, Messenger / Q000235:genetics*; D051381:Rats; D011919:Rats, Inbred Strains
D016189:Dystrophin; D015345:Oligonucleotide Probes; D012333:RNA, Messenger; D012313:RNA