Histidine-rich glycoprotein as a negative acute phase reactant.
Serum histidine-rich glycoprotein was determined by the Laurell method in patients with acute inflammation, which negatively correlated with C-reactive protein (P less than 0.005). In sequential observations, this negative relationship was apparently confirmed. Thus histidine-rich glycoprotein acts as a negative acute phase reactant.
Section of Internal Medicine, Kobe Kyodo Hospital, Japan.
K
K
Saigo
A
A
Yoshida
R
R
Ryo
N
N
Yamaguchi
L L
LL
Leung
D000209:Acute-Phase Proteins; D002097:C-Reactive Protein / Q000032:analysis; D006023:Glycoproteins / Q000097:blood*; D006801:Humans; D008107:Liver Diseases / Q000097:blood; D011506:Proteins / Q000032:analysis*; D012016:Reference Values; D000099053:Histidine-Rich Glycoprotein
D000209:Acute-Phase Proteins; D006023:Glycoproteins; D011506:Proteins; D000099053:Histidine-Rich Glycoprotein; D002097:C-Reactive Protein