[Prevention of dialysis-induced leukopenia and hypoxemia by using low-molecular dextran].
In 10 patients with end stage renal failure on chronic haemodialysis the effect was studied of the low molecular dextran (filling the dialyser) on the peripheral blood leucocyte count and some gasometric and ventilatory parameters during and after haemodialysis (HD). When the dialyser was filled with dextran neither the leucocyte count nor the arterial PaO2 were altered but on the 10th minute of HD without dextran both those values fell. The decrease of the ventilation rate (VE), of the alveolar oxygen tension (PAO2) as well as of the index of oxygen utilisation (VIO2/VE) within the first hour of HD with or without dextran might be due to the absorption of the CO2 by dialysing fluid.
Kliniki Nefrologii Instytutu Chorób Wewnetrznych Akademii Medycznej im. K. Marcinkowskiego w Poznaniu, kierownik.
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Wanic-Kossowska
D000328:Adult; D000368:Aged; D003911:Dextrans / Q000008:administration & dosage*; D015314:Dialysis Solutions; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000209:etiology / Q000517:prevention & control*; D007676:Kidney Failure, Chronic / Q000097:blood / Q000628:therapy*; D007970:Leukopenia / Q000209:etiology / Q000517:prevention & control*; D008297:Male; D008875:Middle Aged; D008970:Molecular Weight; D006435:Renal Dialysis / Q000009:adverse effects
D003911:Dextrans; D015314:Dialysis Solutions
Zapobieganie leukopenii i hipoksemii dializacyjnej poprzez zastosowanie dekstranu niskoczasteczkowego.