Species differences in the activation of mianserin to a cytotoxic metabolite.
Department of Pharmacology and Therapeutics, University of Liverpool, UK.
P
P
Roberts
N R
NR
Kitteringham
B K
BK
Park
D000818:Animals; D001711:Biotransformation; D002845:Chromatography; D006168:Guinea Pigs; D006801:Humans; D008297:Male; D008803:Mianserin / Q000031:analogs & derivatives / Q000378:metabolism / Q000493:pharmacokinetics* / Q000633:toxicity; D008862:Microsomes, Liver / Q000378:metabolism; D011817:Rabbits; D051381:Rats; D013045:Species Specificity
D008803:Mianserin; C056517:desmethylmianserin