The G protein-channel connection.
Recent interest in the regulation of ion currents by hormones and neurotransmitters has focused on the role of G proteins as modulators. Which G proteins are involved? How is this regulation achieved? Initial results suggest that the pathways and mechanisms of action are complex and that delineation of this area of regulation has just begun.
Sternweis
P C
PC
Department of Pharmacology, University of Texas, Southwestern Medical Center, Dallas 75235.
Pang
I H
IH
D000818:Animals; D019204:GTP-Binding Proteins / Q000502:physiology*; D007473:Ion Channels / Q000187:drug effects* / Q000502:physiology; D015290:Second Messenger Systems
D007473:Ion Channels; D019204:GTP-Binding Proteins