Antiepileptic activity of 1,3-dihexadecanoylamino-2-valproyl-propan-2-ol, a prodrug of valproic acid endowed with a tropism for the central nervous system.
F
F
Mergen
D M
DM
Lambert
J C
JC
Goncalves Saraiva
J H
JH
Poupaert
P
P
Dumont
D000284:Administration, Oral; D000818:Animals; D000927:Anticonvulsants / Q000138:chemical synthesis / Q000493:pharmacokinetics* / Q000627:therapeutic use; D002490:Central Nervous System / Q000378:metabolism*; D015195:Drug Design; D004597:Electroshock; D004827:Epilepsy / Q000188:drug therapy / Q000378:metabolism*; D008297:Male; D051379:Mice; D011355:Prodrugs / Q000493:pharmacokinetics* / Q000627:therapeutic use; D013329:Structure-Activity Relationship; D014635:Valproic Acid / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000493:pharmacokinetics / Q000627:therapeutic use
D000927:Anticonvulsants; D011355:Prodrugs; C073602:1,3-dihexadecanoylamino-2-valproyl-propan-ol; D014635:Valproic Acid