[Benign pleural fibroma. An anatomo-clinical study of 10 cases].
We present an anatomical-clinical analysis of ten cases of benign pleural fibroma. This tumour was discovered in a systematic fashion in 8 of the 10 cases and fortuitously in one. Recent radiological examinations enabled the diagnosis to be suspected. Computerised tomography most often precisely identified the pleural topography and imagery by nuclear magnetic resonance in one case visualised fibrous tissue (with a zone of low signals on the scale in T2). The final diagnosis was achieved at the same time as the treatment when an exploratory thoracotomy was performed. In all the cases there was a tumour composed of fusiform cells covered by normal epithelium coming from the viscera pleura 8 times out of 10. The ultrastructure examination and immunohistochemistry of the fusiform cells (Vimentin plus, EMA-, KL1-) allowed for a differentiation of these tumours of connective tissue origin from tumours of mesothelial origin. These analyses constitute an argument in favour of the fibroblastic origin of pleural fibromas.
Moro
D
D
Service de Pneumologie, C.H.U. A.-Michallon, Grenoble.
Brambilla
E
E
Brichon
P Y
PY
Claraz
C
C
Coulomb
M
M
Sarrazin
R
R
Paramelle
B
B
Brambilla
C
C
D000328:Adult; D000368:Aged; D005260:Female; D005347:Fibroblasts / Q000473:pathology; D005350:Fibroma / Q000032:analysis / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D008297:Male; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000032:analysis / Q000473:pathology*; D014746:Vimentin / Q000032:analysis
D014746:Vimentin; D007633:Keratins
Les fibromes pleuraux bénins. Etude anatomo-clinique de 10 cas.