Striking feature of alpha-fetoprotein (AFP): stimulation of the phagocytic capabilities of human blood platelets.
In concentrations from 2.5 x 10(3) to 480 x 10(3) ng/ml AFP is able to increase the phagocytic index and the phagocytizing percentage of human blood platelets in vitro conditions. This effect is dependent on the dose of AFP and time of incubation.
Department of Clinical Laboratory Diagnostics, Medical Academy, Białystok, Poland.
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Mantur
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Prokopowicz
D001792:Blood Platelets / Q000502:physiology*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D066298:In Vitro Techniques; D010587:Phagocytosis / Q000187:drug effects*; D000509:alpha-Fetoproteins / Q000494:pharmacology*
D000509:alpha-Fetoproteins