Bleomycin-induced pulmonary toxicity.
Bleomycin is recognized to cause an interstitial pneumonitis that can lead to fibrosis. Although its occurrence may be sporadic, some factors may increase the risk of such a pulmonary reaction. In this article the clinical setting and presentation, radiographic manifestations, pathologic findings, and the prognosis of bleomycin-induced interstitial fibrosis are described. Additionally, the role of pulmonary function tests in monitoring patients for toxicity is discussed.
Jules-Elysee
K
K
Division of Pulmonary Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York.
White
D A
DA
D000328:Adult; D000368:Aged; D001761:Bleomycin / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D011658:Pulmonary Fibrosis / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D011859:Radiography
D001761:Bleomycin