Role of T-cell subsets in bacterial infections.
Classic functional partitioning of T-cell subsets is being questioned: in many bacterial and protozoan infections, CD8 T cells play a role in protection; two types of CD4 T helper cells have been characterized, one protective, the other exacerbating disease; finally, gamma delta T cells have been implicated in the host response to certain bacteria. Moreover, evidence is accumulating that, in addition to T-cell helper functions, cytolytic T-cell functions participate in antibacterial immunity.
University of Ulm, Germany.
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Kaufmann
D000818:Animals; D001424:Bacterial Infections / Q000276:immunology*; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D008213:Lymphocyte Activation; D051379:Mice; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000276:immunology; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology
D016692:Receptors, Antigen, T-Cell, gamma-delta