[Prenatal DNA-diagnosis of Duchenne muscular dystrophy].
Two prenatal diagnoses were carried out by the technique of intragenic polymorphous marker detecting heterozygosity in pregnant women in the families with cases of Duchenne muscular dystrophy. In both cases the DNA fragment from pERT87-15 region was amplified. This fragment includes a polymorphous site in BamHI region of recognition. DNA analyses of the families members have been made and the genetical risk has been calculated by the Bayes method. The prognoses for both fetuses are good.
Evgrafov
O V
OV
Poliakov
A V
AV
Zaĭtseva
S P
SP
Vinogradov
S V
SV
Bakharev
V A
VA
Mil'man
F A
FA
Lisova
L P
LP
Zaretskaia
N V
NV
Malygina
N A
NA
Badalian
L O
LO
D001483:Base Sequence; D015245:Deoxyribonuclease BamHI; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis; D005784:Gene Amplification; D005819:Genetic Markers; D006801:Humans; D008969:Molecular Sequence Data; D009136:Muscular Dystrophies / Q000175:diagnosis*; D010375:Pedigree; D012150:Polymorphism, Restriction Fragment Length; D011247:Pregnancy; D011296:Prenatal Diagnosis
D005819:Genetic Markers; D015245:Deoxyribonuclease BamHI
Prenatal'naia DNK-diagnostika miodistrofii Diushenna.