Effect of contralateral carotid ligation on experimental carotid artery aneurysm in the rat.
Haemodynamic factors in the formation and development of saccular aneurysms have been widely studied. Saccular aneurysms could appear and grow at the side of the increased blood flow. The effects of contralateral carotid ligation on the formation and growth of our experimental saccular aneurysms were studied. Measurement and pathological examination showed that the haemodynamic changes could facilitate the development of saccular aneurysms, but by itself could not bring about their formation.
Department of Neurosurgery, Free University Hospital, Amsterdam, The Netherlands.
Y Z
YZ
Gao
H A
HA
van Alphen
W
W
Kamphorst
D000783:Aneurysm / Q000473:pathology*; D000818:Animals; D002339:Carotid Arteries / Q000473:pathology / Q000601:surgery*; D002340:Carotid Artery Diseases / Q000473:pathology*; D004195:Disease Models, Animal; D005260:Female; D006439:Hemodynamics; D008026:Ligation; D051381:Rats