Localization of acidic fibroblast growth factor (aFGF) mRNA in mouse and bovine retina by in situ hybridization.
Acidic fibroblast growth factor (aFGF) mRNA has been detected in adult mouse or bovine retina by in situ hybridization with bovine aFGF cDNA clones. It is localized on ganglion cell layer, inner nuclear layer, photoreceptors and slightly on pigmented epithelium. This synthesis of aFGF in highly specialized retinal cell types is discussed in the framework on current views about the role of FGF in retinal cell biology.
Unité de Recherches Gérontologiques, U.118-INSERM, Unité affiliée CNRS, Association Claude Bernard, Paris, France.
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Jacquemin
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Halley
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Alterio
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Laurent
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Courtois
J C
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Jeanny
D000818:Animals; D003001:Cloning, Molecular; D015342:DNA Probes; D016220:Fibroblast Growth Factor 1 / Q000235:genetics*; D051379:Mice; D009693:Nucleic Acid Hybridization; D012333:RNA, Messenger / Q000032:analysis / Q000235:genetics*; D015183:Restriction Mapping; D012160:Retina / Q000166:cytology / Q000378:metabolism*
D015342:DNA Probes; D012333:RNA, Messenger; D016220:Fibroblast Growth Factor 1