Mapping and characterization of neutralizing epitopes of glycoproteins gIII and gp50 of the Indiana-Funkhauser strain of pseudorabies virus.
Neutralizing monoclonal antibodies directed against pseudorabies glycoproteins gIII or gp50 were produced. Using these antibodies in competitive binding ELISAs, three overlapping epitopes for gp50 and two nonoverlapping epitopes for gIII were mapped.
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National Animal Disease Center, USDA, Ames, Iowa.
Mengeling
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D000911:Antibodies, Monoclonal / Q000032:analysis / Q000302:isolation & purification; D000914:Antibodies, Viral / Q000032:analysis; D000956:Antigens, Viral / Q000235:genetics* / Q000276:immunology; D001667:Binding, Competitive; D002874:Chromosome Mapping; D004797:Enzyme-Linked Immunosorbent Assay; D000939:Epitopes / Q000235:genetics* / Q000276:immunology; D006023:Glycoproteins / Q000235:genetics* / Q000276:immunology; D011558:Herpesvirus 1, Suid / Q000235:genetics* / Q000276:immunology; D009500:Neutralization Tests; D014759:Viral Envelope Proteins / Q000235:genetics* / Q000276:immunology; D014764:Viral Proteins / Q000235:genetics* / Q000276:immunology
D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D000956:Antigens, Viral; D000939:Epitopes; D006023:Glycoproteins; D014759:Viral Envelope Proteins; D014764:Viral Proteins; C042966:pseudorabies virus glycoproteins