[Changes in the functional activity of T-lymphocytes after administration of stelazine].
It has been established that stelazine administered in the dose corresponding to the therapeutic one is capable of inhibiting the proliferative activity of T lymphocytes and production of IL-2 in experiments in vitro. It is assumed that decrease of these characteristics in schizophrenic patients is related to the systematic intake of neuroleptics.
L V
LV
Androsova
T P
TP
Sekirina
D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D066298:In Vitro Techniques; D007376:Interleukin-2 / Q000096:biosynthesis; D007958:Leukocyte Count; D008213:Lymphocyte Activation / Q000187:drug effects / Q000502:physiology; D008875:Middle Aged; D012559:Schizophrenia / Q000188:drug therapy / Q000276:immunology*; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology* / Q000378:metabolism / Q000473:pathology; D014268:Trifluoperazine / Q000008:administration & dosage*
D014150:Antipsychotic Agents; D007376:Interleukin-2; D014268:Trifluoperazine
Izmenenie funktsional'noĭ aktivnosti T-limfotsitov pod vliianiem stelazina.