Glutamate-immunoreactive neurons of the central amygdaloid nucleus projecting to the subretrofacial nucleus of SHR and WKY rats: a double-labeling study.
Glutamate immunoreactivity was found in 9%, in the case of Wistar Kyoto rats (WKY), and 14%, in the case of spontaneously hypertensive rats (SHR), of neurons located in the medial division of the central amygdaloid nucleus (CeM) projecting ipsilaterally to the subretrofacial nucleus (SRF) in the rostral ventrolateral medulla using a double-labeling technique in combination with glutamate immunocytochemistry. The results indicate that possibly-glutamatergic neurons located in the CeM project to the SRF, in which vasomotor neurons are present, suggesting involvement of the CeM in blood pressure regulation. No significant difference was found between the distribution of labeled CeM neurons in SHR and WKY rats.
Department of Physiology 1st Division, Gunma University School of Medicine, Maebashi, Japan.
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Takayama
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Miura
D000344:Afferent Pathways / Q000033:anatomy & histology; D000679:Amygdala / Q000737:chemistry / Q000166:cytology*; D000818:Animals; D001794:Blood Pressure / Q000502:physiology; D004558:Electric Stimulation; D005971:Glutamates / Q000032:analysis*; D018698:Glutamic Acid; D006973:Hypertension / Q000503:physiopathology; D008297:Male; D008526:Medulla Oblongata / Q000033:anatomy & histology*; D051381:Rats; D011918:Rats, Inbred SHR / Q000033:anatomy & histology* / Q000378:metabolism; D011921:Rats, Inbred WKY / Q000033:anatomy & histology* / Q000378:metabolism; D014666:Vasomotor System / Q000502:physiology
D005971:Glutamates; D018698:Glutamic Acid