[Ultrastructural relief of unaffected mucosa in recurrent oral ulcer patients. 2].
Electron microscopy was performed on clinically normal vestibular mucosa biopsies of two patients affected with recurrent oral ulcers. Apoptotic cells were absent from vestibular mucosa; this is in contrast with the pathogenetic theory proposed by Honma et al., 1985 (1). Only a few modifications in the keratinization process (intracytoplasmic desmosomes, electrondense granules in basal keratinocytes) and an unusually high number of dendritic cells were found; dendritic cells could be involved in local immunological iperreactivity, responsible for the ulcers of these subjects.
Bergamini
M
M
Università degli Studi di Firenze.
Tonelli
P
P
Sanvenero
S
S
Galeotti
F
F
D003713:Dendritic Cells / Q000648:ultrastructure; D006801:Humans; D007633:Keratins; D008855:Microscopy, Electron, Scanning; D009061:Mouth Mucosa / Q000473:pathology / Q000648:ultrastructure*; D013281:Stomatitis, Aphthous / Q000276:immunology / Q000473:pathology*
D007633:Keratins
Rilievi ultrastrutturali su mucosa indenne di portatori di ulcere orali ricorrenti. Nota II.