Idiopathic polypoidal choroidal vasculopathy (IPCV).
Eleven patients, 40 to 71 years old, had a choroidal vasculopathy that led to hemorrhagic and exudative macular degeneration. The patients had peculiar polypoidal, subretinal, vascular lesions associated with serious and hemorrhagic detachments of the retinal pigment epithelium. This macular disorder, which we have named idiopathic polypoidal choroidal vasculopathy (IPCV), appears to represent a distinct entity that differs clinically and demographically from age-related macular degeneration (AMD) and other macular diseases associated with subretinal neovascularization. Recognition of this condition is important because it may have specific risk factors, natural course, and management considerations that differ from those of age-related macular degeneration.
LuEsther T. Mertz Retinal Research Lab, Manhattan Eye, Ear and Throat Hospital, New York, NY 10021.
L A
LA
Yannuzzi
J
J
Sorenson
R F
RF
Spaide
B
B
Lipson
D000328:Adult; D000368:Aged; D015862:Choroid Diseases / Q000150:complications / Q000473:pathology* / Q000601:surgery; D002832:Choroid Hemorrhage / Q000209:etiology; D005130:Eye Hemorrhage / Q000209:etiology; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D008028:Light Coagulation; D008268:Macular Degeneration / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic; D010857:Pigment Epithelium of Eye / Q000473:pathology; D011379:Prognosis; D012163:Retinal Detachment / Q000209:etiology; D014792:Visual Acuity