A dual anti-tumor effect of a combination of interferon-alpha and 5-flurouracil or 2-chlorodeoxyadenosine on natural killer (NK) cell mediated cytotoxicity.
Reiter
Z
Z
Department of Biology, Indiana University, Bloomington 47405.
Ozes
O N
ON
Tomson
S
S
Blatt
L M
LM
Taylor
M W
MW
D015762:2-Chloroadenosine / Q000031:analogs & derivatives* / Q000494:pharmacology; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000964:Antimetabolites, Antineoplastic / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D017338:Cladribine; D003602:Cytotoxicity, Immunologic / Q000187:drug effects*; D003839:Deoxyadenosines / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D005260:Female; D005472:Fluorouracil / Q000494:pharmacology*; D006801:Humans; D007370:Interferon Type I / Q000494:pharmacology*; D007694:Killer Cells, Natural / Q000187:drug effects* / Q000276:immunology; D007700:Kinetics; D007943:Leukemia, Hairy Cell; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive; D011994:Recombinant Proteins; D012514:Sarcoma, Kaposi / Q000209:etiology; D002583:Uterine Cervical Neoplasms
D000964:Antimetabolites, Antineoplastic; D003839:Deoxyadenosines; D007370:Interferon Type I; D011994:Recombinant Proteins; D015762:2-Chloroadenosine; D017338:Cladribine; D005472:Fluorouracil