9p monosomy in a patient with Gilles de la Tourette's syndrome.
Gilles de la Tourette's syndrome (GTS) is a genetic disorder characterized by multiple motor and vocal tics, obsessive-compulsive disorder, and attention-deficit disorder. Family studies support the presence of an autosomal dominant gene; however, to date, an assignment for the GTS locus has not been made. We present the case of a boy with GTS and a deletion of the terminal portion of the short arm of chromosome 9, del(9)(qter----p2304:).
Department of Pathology, Baylor College of Medicine, Houston, TX 77030.
L D
LD
Taylor
D B
DB
Krizman
J
J
Jankovic
A
A
Hayani
P C
PC
Steuber
F
F
Greenberg
R G
RG
Fenwick
C T
CT
Caskey
D000293:Adolescent; D002899:Chromosomes, Human, Pair 9; D015342:DNA Probes; D006801:Humans; D007370:Interferon Type I / Q000235:genetics; D007621:Karyotyping; D008297:Male; D009006:Monosomy; D012150:Polymorphism, Restriction Fragment Length; D005879:Tourette Syndrome / Q000150:complications / Q000235:genetics*
D015342:DNA Probes; D007370:Interferon Type I