Catheter biofilms and recurrent CAPD peritonitis.
To study the significance of biofilm bacteria in CAPD peritonitis, in a preliminary study, we compared the growth of planktonic and biofilm bacteria by parallel cultures of the same PD effluent in 14 patients with CAPD-associated peritonitis. Planktonic bacteria were isolated by routine microbiologic culture techniques and biofilm bacteria by the use of a modified Robbins' device (MRD). Antibiotic sensitivity or MIC's of bacterial strains isolated by the two techniques were compared. This comparison of the IC identified a subgroup of patients who developed recurrent antibiotic resistant biofilm-induced peritonitis and their peritoneal catheters were subsequently removed.
University of Alberta, Canada.
M K
MK
Dasgupta
K
K
Kowalewska-Grochowska
M
M
Larabie
J W
JW
Costerton
D000328:Adult; D000368:Aged; D001419:Bacteria / Q000254:growth & development*; D002404:Catheterization; D015314:Dialysis Solutions; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*; D010538:Peritonitis / Q000209:etiology / Q000382:microbiology*; D012008:Recurrence
D015314:Dialysis Solutions