Catecholamine- and endotoxin-influenced cutaneous basophil hypersensitivity in chickens.
1. Catecholamines suppress cutaneous basophil hypersensitivity (CBH) to intradermal phytohemagglutinin (PHA-P) challenge in chickens. 2. E. coli 0127:B8 endotoxin, reserpine, and propranolol prevented a norepinephrine-induced suppression of CBH. 3. PHA-P induced CBH appeared to be mediated through a beta-adrenergic receptor mechanism associated with plasma corticosterone in chickens.
North Carolina State University Department of Poultry Science, Raleigh 27695-7635.
H M
HM
Brown-Borg
F W
FW
Edens
P M
PM
Grant
D000818:Animals; D001491:Basophils / Q000276:immunology*; D002395:Catecholamines / Q000037:antagonists & inhibitors / Q000494:pharmacology* / Q000502:physiology; D002645:Chickens; D003877:Dermatitis, Contact / Q000276:immunology / Q000473:pathology; D004731:Endotoxins / Q000494:pharmacology*; D004926:Escherichia coli; D006968:Hypersensitivity, Delayed / Q000139:chemically induced / Q000276:immunology* / Q000473:pathology; D007271:Injections, Intradermal; D010835:Phytohemagglutinins / Q000008:administration & dosage; D011433:Propranolol / Q000494:pharmacology; D012110:Reserpine / Q000494:pharmacology
D002395:Catecholamines; D004731:Endotoxins; D010835:Phytohemagglutinins; D012110:Reserpine; D011433:Propranolol