Adaptation of human rotavirus to cell culture and characterization of the isolated strain.
Human rotavirus strain 649 was isolated from a child with clinical picture of acute intestinal infection in the West European part of the U.S.S.R. This strain was adapted to MA-104 (rhesus monkey kidney) cells. By electrophoresis and haemagglutination it differed from the human rotavirus strain Wa and from the simian strain Sa-11. The productive reproduction of human rotavirus strain 649 may allow its use for the preparation of antigens for diagnostic, immunoprophylaxis, and treatment.
Gudkov
V G
VG
Belorussian Research Institute of Epidemiology and Microbiology, Minsk, U.S.S.R.
Rytik
P G
PG
Shumko
V V
VV
Virinskaya
A S
AS
Nepljuev
I V
IV
Ilkevich
J G
JG
D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology; D000956:Antigens, Viral / Q000276:immunology; D002478:Cells, Cultured; D003429:Cross Reactions; D005243:Feces / Q000382:microbiology; D005759:Gastroenteritis / Q000382:microbiology*; D006801:Humans; D007668:Kidney; D008253:Macaca mulatta; D012401:Rotavirus / Q000145:classification / Q000276:immunology / Q000302:isolation & purification*; D012400:Rotavirus Infections / Q000382:microbiology*; D014776:Virus Cultivation
D000914:Antibodies, Viral; D000956:Antigens, Viral