[Drug therapy of non-ulcer dyspepsia].
The results of placebo-controlled clinical trials of the treatment of non-ulcer dyspepsia with antacids, H2-receptor blockers, pirenzepine, sucralfate and colloidal bismuth subcitrate are reviewed. The methodological difficulties involved in connection with clinical trials of treatment of a vaguely defined condition such as non-ulcer dyspepsia are discussed with particular attention to the criteria for inclusion, assessment of effect and selection bias. None of the pharmacological agents have proved convincingly better than a placebo but sub-groups of the condition probably exist where symptomatic effects may be anticipated.
Odense Sygehus, medicinsk gastroenterologisk afdeling.
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D000863:Antacids / Q000627:therapeutic use; D001729:Bismuth / Q000627:therapeutic use; D004415:Dyspepsia / Q000188:drug therapy*; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D009853:Omeprazole / Q000627:therapeutic use; D010890:Pirenzepine / Q000627:therapeutic use; D013392:Sucralfate / Q000627:therapeutic use
D000863:Antacids; D006635:Histamine H2 Antagonists; D010890:Pirenzepine; D013392:Sucralfate; D009853:Omeprazole; D001729:Bismuth
Medikamentel behandling af non-ulcus dyspepsi.