Localized depigmentation after steroid injection of a ganglion cyst on the hand.
Presented is the case of a man who had localized depigmentation after local injection of triamcinolone diacetate. Search of the literature indicates that this is a rare complication of such therapy. Localized depigmentation may have important cultural implications for dark-skinned patients. There is some experimental evidence that less-potent and shorter-acting steroid preparations have a lower likelihood for depigmenting side effects, and such agents may be more appropriate when injecting subcutaneous structures to prevent this complication.
Department of Emergency Medicine, University of Kentucky College of Medicine, Lexington 40536.
J S
JS
Stapczynski
D000328:Adult; D004814:Epidermal Cyst / Q000628:therapy*; D006225:Hand; D006801:Humans; D008297:Male; D010859:Pigmentation Disorders / Q000139:chemically induced*; D008249:Protein-Lysine 6-Oxidase / Q000037:antagonists & inhibitors; D012880:Skin Pigmentation / Q000187:drug effects*; D013396:Suction; D014221:Triamcinolone / Q000009:adverse effects / Q000031:analogs & derivatives*
D014221:Triamcinolone; C030262:triamcinolone diacetate; D008249:Protein-Lysine 6-Oxidase