[Lactate dehydrogenase in the esophageal mucosa of patients with different types of esophagitis].
Total lactate dehydrogenase (LDH) activity and its isozymic spectrum were examined in esophageal tissue biopsy specimens from 56 patients with various esophagitides. For control esophageal mucosa specimens from 30 subjects dead in accidents were examined. The findings evidence a significant increase of the total LDH activity in the patients with erosive esophagitis and more so in those with the ulcerative condition. Increased share of the fifth fraction parallelled by a drop of the first LDH fraction were detected in the esophageal mucosa of the patients suffering from erosive and ulcerative esophagitides. The detected disorders of redistribution of LDH isoform activities in erosive and ulcerative esophagitides are less manifest than in malignant tumors but show the same tendency.
Bazarova
R I
RI
Lalaeva
N V
NV
D001706:Biopsy; D004796:Clinical Enzyme Tests / Q000379:methods*; D003937:Diagnosis, Differential; D004941:Esophagitis / Q000175:diagnosis*; D004942:Esophagitis, Peptic / Q000175:diagnosis; D004947:Esophagus / Q000201:enzymology* / Q000473:pathology; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000032:analysis*; D009092:Mucous Membrane / Q000201:enzymology / Q000473:pathology
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase
Issledovanie laktatdegidrogenazy v slizistoĭ obolochke pishchevoda bol'nykh razlichnymi ézofagitami.