Ras-like genes and gene families in the mouse.
Four human RAS-like cDNAs and a mouse genomic DNA fragment were used to define novel mouse Ras-like genes and gene families. Inheritance of DNA restriction fragment length variants associated with these genes in recombinant inbred and backcross mice allowed definition of 12 genetic loci, nine of which were mapped, to chromosomes (Chr) 2, 4, 7, 8, 9, and 17. Two possible clusters of Ras-like and/or G protein genes were identified, on Chrs 9 and 17.
Department of Biochemistry, New York University Medical Center, New York 10016.
G
G
Drivas
R
R
Massey
H Y
HY
Chang
M G
MG
Rush
P
P
D'Eustachio
D000818:Animals; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D003433:Crosses, Genetic; D015342:DNA Probes; D019204:GTP-Binding Proteins / Q000235:genetics*; D011905:Genes, ras / Q000235:genetics*; D051379:Mice; D008815:Mice, Inbred Strains; D005810:Multigene Family / Q000235:genetics; D012150:Polymorphism, Restriction Fragment Length; D009626:Terminology as Topic
D015342:DNA Probes; D019204:GTP-Binding Proteins