[Evolution of in vivo and in vitro tests during specific immunotherapy against hymenoptera venoms].
In this study, on a population of 26 patients with systemic reactions after hymenoptera stings, different immunobiological tests have been used to confirm the sensitivity to hymenoptera venom. These 26 patients were divided into two groups according to the stage of their immunotherapy: group 1 (n = 8) included all assessments from day 0 (before IT) and group 2 (n = 16) the assessments at 1 and 2 years during IT. In general, there was a good correlation between skin tests, RAST and histamine release. The results show that the IgE level seems to be more informative than histamine release and that measurement of the specific IgE level is more sensitive with Allerbio allergen compared with other allergens. However these preliminary results must be confirmed on a statistically significant number of patients. HL by Agf is less sensitive than that done with Ags.
Laboratoire d'Immuno-Allergologie, CHRU, Angers.
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A
Sabbah
M G
MG
Heulin
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I
Soulière
D001514:Bee Venoms / Q000009:adverse effects*; D003888:Desensitization, Immunologic; D006636:Histamine Release; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000209:etiology / Q000276:immunology* / Q000628:therapy; D007073:Immunoglobulin E / Q000032:analysis; D007158:Immunologic Techniques; D011852:Radioallergosorbent Test; D012882:Skin Tests; D014862:Wasp Venoms / Q000009:adverse effects*
D001514:Bee Venoms; D014862:Wasp Venoms; D007073:Immunoglobulin E
Evolution des tests in vivo et in vitro au cours de l'immunothérapie spécifique au venin d'hyménoptère.