Bilingual language processing after a lesion in the left thalamic and temporal regions. A case report with early childhood onset.
This case study concerns an 18-year-old bilingual girl who suffered a radiation lesion in the left (dominant) thalamic and temporal region when she was 4 years old. Language and memory assessment revealed deficits in auditory short-term memory, auditory word comprehension, nonword repetition, syntactic processing, word fluency, and confrontation naming tasks. Both languages (English and Dutch) were found to be affected in a similar manner, despite the fact that one language (English) was acquired before and the other (Dutch) after the period of lesion onset. Most of the deficits appear to be related to verbal (short-term) memory dysfunction. Several hypotheses of subcortical involvement in memory processes are discussed with reference to existing theories in this area.
van Lieshout
P
P
Nijmegen Institute for Cognition Research and Information Technology (NICI), University of Nijmegen, The Netherlands.
Renier
W
W
Eling
P
P
de Bot
K
K
Slis
I
I
D000293:Adolescent; D000849:Anomia / Q000503:physiopathology; D001037:Aphasia / Q000175:diagnosis / Q000503:physiopathology*; D001925:Brain Damage, Chronic / Q000175:diagnosis / Q000503:physiopathology*; D001932:Brain Neoplasms / Q000532:radiotherapy; D004292:Dominance, Cerebral / Q000502:physiology*; D004828:Epilepsies, Partial / Q000503:physiopathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007802:Language; D008279:Magnetic Resonance Imaging; D009483:Neuropsychological Tests; D011832:Radiation Injuries / Q000503:physiopathology; D013702:Temporal Lobe / Q000503:physiopathology* / Q000528:radiation effects; D013787:Thalamic Nuclei / Q000503:physiopathology* / Q000528:radiation effects