Adult Wilms' tumor. Cisplatin and etoposide for relapse after adjuvant chemotherapy.
The prognosis for patients with adult Wilms' tumor is poor in contrast to pediatric Wilms' tumor. A 23-year-old patient with Wilms' tumor is described who relapsed twice; initially after adjuvant treatment with abdominal irradiation, vincristine, and actinomycin and again after treatment with high dose doxorubicin. The patient was treated with cisplatin and etoposide and is clear of disease 75 months after presentation. She has given birth to a healthy baby.
Abratt
R P
RP
Department of Radiotherapy, Groote Schuur Hospital, Cape Town, South Africa.
du Preez
H M
HM
Kaschula
R
R
D000328:Adult; D002945:Cisplatin / Q000627:therapeutic use*; D003609:Dactinomycin / Q000627:therapeutic use; D005047:Etoposide / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy* / Q000473:pathology; D008175:Lung Neoplasms / Q000556:secondary*; D011379:Prognosis; D014750:Vincristine / Q000627:therapeutic use; D009396:Wilms Tumor / Q000188:drug therapy* / Q000473:pathology
D003609:Dactinomycin; D014750:Vincristine; D005047:Etoposide; D002945:Cisplatin