Relationships among ragweed skin tests and both allergen specific and nonspecific nasal provocation.
Twenty-six patients with ragweed-induced allergic rhinitis were evaluated prior to the onset of seasonal symptoms. Ragweed skin tests and nasal challenges were performed 2 weeks after histamine nasal provocation. A correlation between ragweed skin tests and nasal challenges was detected (r = .4867, P much less than .01). Histamine challenges did not correlate with either of the other variables. A properly performed skin test predicts nasal reactivity to the same allergen. A clinical role for nonspecific nasal provocation could not be determined.
SMBD-Jewish General Hospital, Montreal, Quebec, Canada.
P
P
Small
N
N
Biskin
D
D
Barrett
D000328:Adult; D000485:Allergens / Q000276:immunology*; D000939:Epitopes; D005260:Female; D006632:Histamine; D006801:Humans; D008297:Male; D009299:Nasal Provocation Tests; D011058:Pollen / Q000276:immunology*; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology; D012882:Skin Tests
D000485:Allergens; D000939:Epitopes; D006632:Histamine