Quantitative analysis of epidermal growth factor in human benign prostatic hyperplasia and prostatic carcinoma and its prognostic significance.
The incidence of prostatic carcinoma (PC) is increasing worldwide. Despite the discovery by Huggins in 1941 of the hormone dependency of this tumour, the overall prognosis and survival for patients with advanced disease has not changed. The prognosis for individual patients with PC cannot be accurately predicted by factors such as clinical stage and histological differentiation of the tumour. There is therefore a need to investigate new prognosis factors to assess their role.
Royal Postgraduate Medical School, Hammersmith Hospital, London, U.K.
N
N
Shaikh
L
L
Lai
J
J
McLoughlin
D
D
Clark
G
G
Williams
D000368:Aged; D004815:Epidermal Growth Factor / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011470:Prostatic Hyperplasia / Q000378:metabolism*; D011471:Prostatic Neoplasms / Q000032:analysis*
D004815:Epidermal Growth Factor