Neurotransmitters and neuromodulators in the basal ganglia.
The basal ganglia have become a focus for work on neurotransmitter interactions in the brain. These structures contain a remarkable diversity of neuroactive substances, organized into functional subsystems that have unique developmental histories and vulnerabilities in neurodegenerative diseases. A new view of the basal ganglia is emerging on the basis of this neurochemical heterogeneity, suggesting that dynamic regulation of transmitter expression may be a key to extrapyramidal function.
Graybiel
A M
AM
Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge 02139.
D000818:Animals; D001479:Basal Ganglia / Q000378:metabolism / Q000502:physiology*; D003342:Corpus Striatum / Q000502:physiology; D005786:Gene Expression Regulation; D006801:Humans; D009434:Neural Pathways / Q000502:physiology; D009479:Neuropeptides / Q000235:genetics / Q000502:physiology; D018377:Neurotransmitter Agents / Q000502:physiology*
D009479:Neuropeptides; D018377:Neurotransmitter Agents