Lymphocyte proliferation in Peyer's patches of Giardia muris-infected mice.
Gastrointestinal immune events in giardiasis are important in controlling infection. In this study, Peyer's patch lymphocytes from mice infected with Giardia muris developed specific, proliferative responses to G. muris antigen. This proliferation correlated with clearance of infection. Further understanding of the gut immune response will be helpful in developing immunoprophylactic strategies in the control of giardiasis.
Department of Medicine, University of Connecticut School of Medicine, Farmington 06032.
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D000818:Animals; D000953:Antigens, Protozoan / Q000276:immunology*; D000939:Epitopes; D005260:Female; D005873:Giardiasis / Q000276:immunology*; D008213:Lymphocyte Activation / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D010581:Peyer's Patches / Q000276:immunology*
D000953:Antigens, Protozoan; D000939:Epitopes