Applicability of high-performance liquid chromatography--continuous-flow fast atom bombardment mass spectrometry for simultaneous quantitation of multiple neurochemicals.
A method is described for the analysis of multiple neurochemically important compounds. The technique involves high-performance liquid chromatographic separation in combination with ultraviolet and continuous-flow fast atom bombardment mass spectrometric detection. High-performance liquid chromatographic elution behaviour and relative detection responsiveness as correlated with chemical structure are also presented.
Ikarashi
Y
Y
Department of Neuropsychopharmacology (Tsumura), Gunma University School of Medicine, Japan.
Maruyama
Y
Y
D002794:Choline / Q000032:analysis; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004837:Epinephrine / Q000032:analysis; D018377:Neurotransmitter Agents / Q000032:analysis*; D009638:Norepinephrine / Q000032:analysis; D016339:Spectrometry, Mass, Fast Atom Bombardment / Q000379:methods*
D018377:Neurotransmitter Agents; D002794:Choline; D009638:Norepinephrine; D004837:Epinephrine