[Methodologic characteristics of determining immunologic indices in cerebrospinal fluid].
The authors have tried to adapt the micro-methods for assessment of the peripheral blood immunologic parameters to measurements of these characteristics in the cerebrospinal fluid (CSF) and examined a group of patients to define the diagnostic value of these parameters. Eighteen patients with disseminated sclerosis and 14 normal controls were examined. Relative and absolute counts of T and B lymphocytes, phagocytes, IgA, IgG, and IgM were measured. Normal values of the CSF cellular immunity parameters were determined; these values were essentially shifted in the patients, which recommends the developed methods for assessment of local immunity in nervous system diseases.
Totolian
N A
NA
Georgeos
F
F
Smirnov
A Iu
AIu
Totolian
A A
AA
D000293:Adolescent; D000328:Adult; D002555:Cerebrospinal Fluid / Q000276:immunology*; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid*
Metodicheskie osobennosti opredeleniia immunologicheskikh pokazateleĭ v tserebrospinal'noĭ zhidkosti.