[The contents of gamma-aminobutyric acid and glutamic acid in brain affected by coriaria lactone].
Capillary chromatography was applied to studying the contents of gamma-aminobutyric acid (GABA) and glutamic acid (Glu) in brain affected by coriaria lactone. The results showed that there was a significant increase in the content of Glu whereas no significant change in the content of GABA was noted. The precisions for GABA and Glu were 3.3% and 4.98% and the recoveries of them were 80.5% and 85.2%, respectively. Capillary chromatography is a good method for determining the contents of GABA and Glu in brain, which has the characteristics of rapid and high sensitivity.
School of Pharmacy.
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Xu
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Guo
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Song
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Li
D000818:Animals; D001921:Brain / Q000378:metabolism*; D002849:Chromatography, Gas / Q000379:methods; D005260:Female; D005971:Glutamates / Q000378:metabolism*; D018698:Glutamic Acid; D007783:Lactones / Q000494:pharmacology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D005971:Glutamates; D007783:Lactones; D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid; C049836:coriaria lactone