PrP amyloid plaques in Creutzfeldt-Jakob disease of short duration: immunohistochemical studies of 5 cases from Poland.
We report here PrP-immunohistochemistry performed on brains from CJD cases from Poland. Only one of five definitive CJD cases exhibited typical PrP-immunoreactive kuru-like plaques and this was case of a short duration. We thus confirm the low frequency of PrP plaques in CJD of Eastern and Central European origin.
Dept. Oncology, Medical Academy Lodz, Poland.
P P
PP
Liberski
H
H
Kwiecinski
M
M
Barcikowska
B
B
Mirecka
J
J
Kulczycki
E
E
Kida
P
P
Brown
D C
DC
Gajdusek
D000328:Adult; D000368:Aged; D001921:Brain / Q000378:metabolism*; D007562:Creutzfeldt-Jakob Syndrome / Q000453:epidemiology / Q000378:metabolism*; D005260:Female; D016098:Gerstmann-Straussler-Scheinker Disease / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D018620:PrPSc Proteins; D011328:Prions / Q000378:metabolism*
D018620:PrPSc Proteins; D011328:Prions