Juvenile tinea capitis caused by Trichophyton violaceum. Hepatic reactions during ketoconazole treatment.
A 10-year-old boy with T. violaceum tinea capitis was given systemic ketoconazole therapy. After 4 weeks' treatment, liver enzymes had increased considerably. Ketoconazole treatment was stopped and 3 weeks later the values had returned to normal. Three weeks thereafter the patient was completely cured and no relapses have occurred.
Department of Dermatology, University Hospital, Tromsø, Norway.
B
B
Gasior-Chrzan
S E
SE
Stenvold
E S
ES
Falk
D056486:Chemical and Drug Induced Liver Injury; D002648:Child; D003022:Clotrimazole / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007654:Ketoconazole / Q000009:adverse effects*; D008107:Liver Diseases / Q000201:enzymology; D008297:Male; D012537:Scandinavian and Nordic Countries; D014006:Tinea Capitis / Q000188:drug therapy* / Q000382:microbiology; D014249:Trichophyton
D003022:Clotrimazole; D007654:Ketoconazole