Influences of thiamin on lead intoxication, lead deposition in tissues and lead hematological responses of Tilapia zillii.
1. Lead levels in the blood, kidney, liver, brain and muscle of fish receiving only lead were elevated markedly over the values of both controls and thiamin-treated fish. 2. No statistical difference was observed between the lead levels in bone samples of both fish receiving only lead and thiamin-treated fish. 3. In contrast to the fish receiving only lead the fish treated with thiamin appeared to be healthy and had no lead poisoning signs. 4. Over the period of study, hemoglobin content and red blood cell counts of fish receiving only lead showed significant decreases from the values of both controls and fish treated with thiamin. 5. Hematocrit values and white blood cell counts were uninfluenced by either lead exposure or thiamin treatment at all intervals. 6. The data suggest that thiamin can serve as a promising natural chelator to prevent fish mortality, not only in short term, but also in prolonged exposure.
Ghazaly
K S
KS
Department of Natural History, Faculty of Education, University of Alexandria, Egypt.
D000818:Animals; D004785:Environmental Pollutants / Q000506:poisoning*; D005393:Fish Diseases / Q000097:blood / Q000378:metabolism / Q000517:prevention & control*; D005399:Fishes; D006403:Hematologic Tests; D007855:Lead Poisoning / Q000097:blood / Q000378:metabolism / Q000517:prevention & control / Q000662:veterinary*; D013831:Thiamine / Q000627:therapeutic use*
D004785:Environmental Pollutants; D013831:Thiamine