The role of T-cell subsets and cytokines in the regulation of infection.
The study of immunity to infectious agents has proved valuable for analysing the role of T-cell subsets. This was true when Zinkernagel and Doherty demonstrated MHC restriction using viral and bacterial systems, and was re-emphasized at a recent meeting, where data were presented on the role of T cells and cytokines in viral, bacterial, protozoan and helminth infections. This report summarizes some of the highlights.
Scott
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Dept of Pathobiology, Veterinary School of Medicine, University of Pennsylvania, Philadelphia.
Kaufmann
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SH
D000818:Animals; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D016207:Cytokines / Q000276:immunology*; D006801:Humans; D007109:Immunity; D007239:Infections / Q000276:immunology*; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000276:immunology; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
D016207:Cytokines; D016692:Receptors, Antigen, T-Cell, gamma-delta