Determination of gamma-glutamyl conjugates of monoamines by means of high-performance liquid chromatography with electrochemical detection and application to gastropod tissues.
Catabolism of aminergic neurotransmitters in gastropods appears to be primarily by means of gamma-glutamyl conjugation rather than by oxidative deamination as is typical of vertebrates. High-performance liquid chromatography with electrochemical detection was used to develop a method for the routine measurement of gamma-glutamyl conjugates of dopamine and 5-hydroxytryptamine in gastropod tissues.
Sloley
B D
BD
Department of Zoology, University of Alberta, Edmonton, Canada.
Goldberg
J I
JI
D000818:Animals; D015306:Biogenic Monoamines / Q000032:analysis* / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D004563:Electrochemistry; D005971:Glutamates / Q000378:metabolism*; D018698:Glutamic Acid; D006863:Hydrogen-Ion Concentration; D010084:Oxidation-Reduction; D012908:Snails / Q000378:metabolism*
D015306:Biogenic Monoamines; D005971:Glutamates; D018698:Glutamic Acid