The effect of GRF on the EEG sleep of normal males.
The administration of GRF in young men either before sleep onset or coinciding with sleep onset leads to an immediate significant increase in GH secretion. These increases were not associated with major alterations in sleep including slow-wave sleep.
Department of Psychiatry, University of Pittsburgh, School of Medicine, PA 15213.
D J
DJ
Kupfer
D B
DB
Jarrett
C L
CL
Ehlers
D000328:Adult; D002940:Circadian Rhythm / Q000187:drug effects; D003700:Delta Rhythm; D004569:Electroencephalography / Q000187:drug effects*; D013007:Growth Hormone-Releasing Hormone / Q000494:pharmacology*; D006801:Humans; D008297:Male; D012016:Reference Values; D012894:Sleep Stages / Q000187:drug effects*; D013004:Somatostatin / Q000494:pharmacology*
D013004:Somatostatin; D013007:Growth Hormone-Releasing Hormone