[Ag-negative phenomenon of nucleolar organizers of bone marrow and blood cells in children with acute lymphoblastic leukemia].
The activity of nucleoli-organizing (NOR's) regions was studied in leukemic cells of 53 children with immunologically typical ALL. The Ag-negative type of ALL was found in 9 cases of IA-ALL and Comm(+)-ALL. Dominating cells were not argentaffin. Some cytological peculiarities of Ag-negative cases have been demonstrated: lower presence of E(+)-receptor on circulating lymphoid cells, the greater number of cells with smooth surface which was revealed by the scanning electron microscopic method. The cases when the product of Ag-philic reaction was impossible to be revealed are discussed.
Ikonnikova
O A
OA
Lenskaia
R V
RV
Zatsepina
O V
OV
Kondratchik
K L
KL
Chernov
V M
VM
D000293:Adolescent; D001773:Blood Cells / Q000648:ultrastructure*; D001853:Bone Marrow / Q000648:ultrastructure*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D009697:Nucleolus Organizer Region / Q000648:ultrastructure*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000276:immunology / Q000473:pathology*; D012397:Rosette Formation; D012834:Silver; D013194:Staining and Labeling
D012834:Silver
Fenomen Ag-negativnosti iadryshkovykh organizatorov kletok kostnogo mozga i krovi u deteĭ s ostrym limfoblastnym leĭkozom.