Maternal and perinatal complications in neurofibromatosis during pregnancy.
A total of ten patients with lesions of neurofibromatosis during pregnancy were followed up for pregnancy complications. Seven cases (70%) had hypertensive disorders of pregnancy; four had severe PET (pre-eclamptic toxemia) including one case of eclampsia, one had mild PET and the other two had only mild gestational hypertension. A total of 60% had preterm labor and in none of these did the baby survive; thus perinatal mortality was 600/1000. Mean gestation was 33.0 weeks and mean birthweight was only 1.924 kg. Thus, neurofibromatosis during pregnancy is associated with poor obstetrical outcome and requires greater care.
Department of Obstetrics and Gynaecology-II, Medical College and Hospital, Rohtak, Haryana, India.
J B
JB
Sharma
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N
Gulati
S
S
Malik
D000328:Adult; D001724:Birth Weight; D005260:Female; D005313:Fetal Death / Q000209:etiology*; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007231:Infant, Newborn; D009456:Neurofibromatosis 1 / Q000150:complications*; D007752:Obstetric Labor, Premature / Q000209:etiology; D011225:Pre-Eclampsia / Q000150:complications / Q000209:etiology*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000209:etiology*; D011252:Pregnancy Complications, Neoplastic