Ritodrine-induced agranulocytosis.
This is the first reported case of development of agranulocytosis induced by continuous intravenous infusion of a large quantity of ritodrine hydrochloride for tocolysis. It is suspected that the pathophysiological mechanism is a dose-related toxic reaction and a cell loss maturation process of myelocytes.
Muro
M
M
Department of Obstetrics and Gynecology, Saga Medical School, Japan.
Shono
H
H
Oga
M
M
Ito
Y
Y
Hirai
M
M
Sugimori
H
H
D000328:Adult; D000380:Agranulocytosis / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007752:Obstetric Labor, Premature / Q000517:prevention & control*; D011247:Pregnancy; D011272:Pregnancy, Multiple; D012312:Ritodrine / Q000009:adverse effects* / Q000627:therapeutic use; D015145:Tocolysis
D012312:Ritodrine