[Initial results of combined surgical-medical therapy for metastatic cancer of the stomach].
Fifty patients with advanced gastric cancer underwent chemotherapy in accordance with the FAMTX protocol. Complete tumor remission was achieved in 6 patients and partial remission in 11 patients. In this group 9 patients (tumor stage: T3-4, N2-3, M chi-1) underwent a second-look operation after chemotherapy either to confirm the complete remission or to resect the remaining tumor mass. It is concluded that even in advanced stages of gastric carcinomas a more aggressive approach involving a combination of surgical and chemotherapeutic treatment improves the survival time of these patients.
Chirurgische Universitätsklinik, Hamburg.
D
D
Henne-Bruns
B
B
Kremer
H J
HJ
Weh
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010166:Palliative Care; D012086:Reoperation; D013274:Stomach Neoplasms / Q000188:drug therapy / Q000601:surgery*
D004317:Doxorubicin; D005472:Fluorouracil; D008727:Methotrexate
Erste Ergebnisse eines kombinierten chirurgisch-onkologischen Therapiekonzeptes beim metastasierenden Magenkarzinom.