[Purpura fulminans and C7 deficiency complicated by Pneumocystis carinii pneumonia].
A case of meningococcal purpura fulminans is reported in a 22-year-old woman who also suffered from a congenital deficiency in the seventh component of the complement system. This was her third episode of recurrent meningitis. In the course of her treatment in intensive care, the septic shock was cured, but she developed Pneumocystis carinii pneumonia. Histological investigations revealed abnormalities in her T-cell population, with a very low T-helper (CD4) to T-suppressor (CD8) ratio. Laboratory data showed that she did not have any antibodies to HIV.
Tillant
D
D
Département d'Anesthésie-Réanimation, Hôpital Nord, Marseille.
Albanèse
J
J
Tomachot
L
L
Durbec
O
O
Granthil
C
C
D000328:Adult; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D003184:Complement C7 / Q000172:deficiency*; D003428:Cross Infection / Q000209:etiology*; D005260:Female; D006801:Humans; D008585:Meningitis, Meningococcal / Q000150:complications*; D011020:Pneumonia, Pneumocystis / Q000209:etiology* / Q000276:immunology; D011693:Purpura / Q000209:etiology* / Q000276:immunology; D012008:Recurrence; D012306:Risk
D003184:Complement C7
Purpura fulminans et déficit en C7 compliqué d'une bronchopneumopathie à Pneumocystis carinii.