Localized depigmentation after steroid injection of a ganglion cyst on the hand.
Presented is the case of a man who had localized depigmentation after local injection of triamcinolone diacetate. Search of the literature indicates that this is a rare complication of such therapy. Localized depigmentation may have important cultural implications for dark-skinned patients. There is some experimental evidence that less-potent and shorter-acting steroid preparations have a lower likelihood for depigmenting side effects, and such agents may be more appropriate when injecting subcutaneous structures to prevent this complication.
Stapczynski
J S
JS
Department of Emergency Medicine, University of Kentucky College of Medicine, Lexington 40536.
D000328:Adult; D004814:Epidermal Cyst / Q000628:therapy*; D006225:Hand; D006801:Humans; D008297:Male; D010859:Pigmentation Disorders / Q000139:chemically induced*; D008249:Protein-Lysine 6-Oxidase / Q000037:antagonists & inhibitors; D012880:Skin Pigmentation / Q000187:drug effects*; D013396:Suction; D014221:Triamcinolone / Q000009:adverse effects / Q000031:analogs & derivatives*
D014221:Triamcinolone; C030262:triamcinolone diacetate; D008249:Protein-Lysine 6-Oxidase