Carbohydrate metabolic studies in women using a levonorgestrel/ethinyl estradiol containing triphasic oral contraceptive for eighteen months.
Carbohydrate metabolism was evaluated in 17 women before and after 18 months of triphasic oral contraceptive use. The triphasic oral contraceptive contained levonorgestrel and ethinyl estradiol. An oral glucose tolerance test was utilized and both plasma glucose and insulin levels were measured. There were no significant changes in the glucose levels. The fasting insulin level was raised at the 18-month test, whereas the other insulin values were similar. These results demonstrate that the new triphasic oral contraceptive preparations produce minimal carbohydrate metabolic changes.
Department of Obstetrics and Gynecology, University of South Florida College of Medicine, Tampa 33606.
W N
WN
Spellacy
J C
JC
Tsibris
A B
AB
Ellingson
D000328:Adult; D001786:Blood Glucose / Q000187:drug effects; D003277:Contraceptives, Oral, Combined / Q000008:administration & dosage / Q000494:pharmacology*; D004958:Estradiol / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D005947:Glucose / Q000378:metabolism*; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000097:blood; D016912:Levonorgestrel; D009644:Norgestrel / Q000008:administration & dosage / Q000494:pharmacology*
D001786:Blood Glucose; D003277:Contraceptives, Oral, Combined; D007328:Insulin; D009644:Norgestrel; D004958:Estradiol; D016912:Levonorgestrel; D005947:Glucose