Blood levels of propylene oxide during propylene inhalation and effect on hepatic and nasal cytochrome P-450 concentrations.
Lovelace Inhalation Toxicology Research Institute, Albuquerque, NM 87185.
K R
KR
Maples
A R
AR
Dahl
D000280:Administration, Inhalation; D000475:Alkenes / Q000008:administration & dosage / Q000633:toxicity*; D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000187:drug effects / Q000378:metabolism*; D004305:Dose-Response Relationship, Drug; D004852:Epoxy Compounds / Q000097:blood*; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008297:Male; D008861:Microsomes / Q000187:drug effects / Q000201:enzymology; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology; D009296:Nasal Cavity / Q000187:drug effects / Q000201:enzymology*; D011433:Propranolol / Q000031:analogs & derivatives* / Q000097:blood / Q000378:metabolism; D051381:Rats; D011916:Rats, Inbred F344; D013997:Time Factors
D000475:Alkenes; D004852:Epoxy Compounds; C040851:4'-hydroxypropranolol sulfate ester; D003577:Cytochrome P-450 Enzyme System; D011433:Propranolol; C013658:propylene; C009068:propylene oxide