[Ultrastructural features of heart insufficiency and its correction during the post-asphyxia period].
The ultrastructure of myocardium was studied in the experiments on rats during 24 hours after 6-min mechanical asphyxia with following clinical death. It has been established that the contractile cardiac apparatus of myocytes lesions on the intracellular edema background is the main while energy production process impairs insignificantly. The effectiveness of anti-hypoxia, membrane stability and protease inhibiting preparations for prevention of postresuscitation myocardium lesion was examined. The contrykal protective action, suppressing the proteolytic ferment hyperactivity was determined.
P N
PN
Eskunov
S S
SS
Stepanov
V V
VV
Semchenko
D000818:Animals; D007611:Aprotinin / Q000494:pharmacology*; D001237:Asphyxia; D003327:Coronary Disease / Q000473:pathology*; D006164:Guanylthiourea / Q000494:pharmacology; D006323:Heart Arrest / Q000209:etiology / Q000473:pathology / Q000628:therapy; D006333:Heart Failure / Q000473:pathology; D009206:Myocardium / Q000648:ultrastructure*; D011239:Prednisolone / Q000494:pharmacology; D051381:Rats; D012151:Resuscitation
D007611:Aprotinin; D011239:Prednisolone; D006164:Guanylthiourea
Ul'trastrukturnye priznaki serdechnoĭ nedostatochnosti i ee korrektsiia v postasfiksicheskom periode.