Unusually long survival time after resection and irradiation of a brain metastasis from osteosarcoma.
Cerebral metastases of osteosarcomas are rare. The cases published up to now have manifested only a short relapse-free period of survival. Intracranial filia generation must be anticipated if metastasis formation takes place in the lung. We report here on a young patient who underwent operation for an intraparenchymal cerebral metastasis 76 months after amputation of the left leg due to an osteosarcoma chondroblasticum, and who is, at present, healthy, 13 months after resection. This unusually long survival time is attributed to the good neurological status before craniotomy, early diagnosis, and the improvement of the cytostatic therapy (COSS-80-scheme).
Clinic of Neurosurgery, Rhenisch-Westphalian Technical University (RWTH) Aachen, West Germany.
A
A
Niedeggen
J
J
Weis
R
R
Mertens
J
J
Röther
J
J
Bröcheler
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage; D001932:Brain Neoplasms / Q000556:secondary / Q000601:surgery* / Q000628:therapy; D002648:Child; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D003609:Dactinomycin / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005266:Femoral Neoplasms / Q000473:pathology; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D012516:Osteosarcoma / Q000556:secondary / Q000601:surgery* / Q000628:therapy; D011379:Prognosis
D007370:Interferon Type I; D001761:Bleomycin; D003609:Dactinomycin; D004317:Doxorubicin; D003520:Cyclophosphamide; D002945:Cisplatin; D008727:Methotrexate