[Mechanisms of T-cell-mediated hypersensitivity in mice infected with the intestinal helminth Trichinella spiralis].
Intestinal hypersensitivity reactions during parasitic helminth infections are T-cell-dependent. Little is known about the characteristics of T-cells that initiate and regulate intestinal inflammation or about how they do this. In this paper data are presented that indicate that during Trichinella spiralis infections in mice T-cells regulate intestinal inflammation in the same way that they regulate delayed-type hypersensitivity reactions in the skin and cellular immune responses against tumors.
Parmentier
H K
HK
Vakgroep Infectieziekten en Immunologie, Faculteit Diergeneeskunde, RU Utrecht.
Ruitenberg
E J
EJ
de Weger
R A
RA
van Loveren
H
H
D000818:Animals; D002199:Capillary Permeability; D004751:Enteritis / Q000276:immunology* / Q000503:physiopathology; D000939:Epitopes; D006968:Hypersensitivity, Delayed / Q000276:immunology; D051379:Mice; D013601:T-Lymphocytes / Q000276:immunology*; D014235:Trichinellosis / Q000276:immunology*
D000939:Epitopes
Mechanismen van T-cel-gemedieerde overgevoeligheid in muizen geïnfecteerd met de intestinale helminth Trichinella spiralis.