[Histologic examinations of internal mammary artery, saphenous vein and aorta specimens collected during heart surgery].
133 patients with coronary heart disease were treated surgically. 60 patients had Internal Mammary Artery (IMA) grafting performed together with saphenous vein grafts (IMA group), another 70 patients had saphenous vein grafts only (SVG group). Material for histological examination was intraoperatively taken from saphenous vein and ascending aorta and in IMA group also from the distal part of internal mammary artery. The intensity of atherosclerosis was estimated with 5-grade scale from 0 to 4 (0-no atherosclerosis, 1-minimal, 2-insignificant, 3-moderate, 4-pronounced). To visualize and to assess the blood flow through the internal mammary artery Digital Subtraction Angiography (DSA) was performed between day 6 and day 8 postoperatively in the IMA group. Results obtained were correlated with the intensity of atherosclerosis estimated histologically and the numeric data were statistically analysed. In the IMA grafts mean atherosclerosis intensity was 0.94 which is the evidence of minimal atherosclerotic changes. In saphenous vein the corresponding value was in the IMA group 2.14 and in the SVG group 2.17, in aortic scraps 2.64 in the IMA group and 2.73 in the SVG group. Patients in the SVG group were average 8.4 years older than in the IMA group. The difference is statistically significant. Despite the age difference, the intensity of atherosclerosis was not statistically different in aortic and saphenous vein scraps. Among 63 patients in the IMA group in 31 patients (49.2%) no atherosclerosis was found during histological examination and in 32 patients (50.8%) changes ranged from minimal to moderate. There were no IMA grafts with the pronounced atherosclerosis.(ABSTRACT TRUNCATED AT 250 WORDS)
Hirnle
T
T
Kliniki Chirurgii Serca A.M. we Wrocławiu.
Schlosser
V
V
Spillner
G
G
Fraedrich
G
G
Kameda
T
T
Kuttler
H
H
D000328:Adult; D000368:Aged; D001011:Aorta / Q000473:pathology; D003324:Coronary Artery Disease / Q000473:pathology*; D003327:Coronary Disease / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008323:Mammary Arteries / Q000000981:diagnostic imaging / Q000473:pathology; D008875:Middle Aged; D009204:Myocardial Revascularization; D011859:Radiography; D012501:Saphenous Vein / Q000473:pathology
Badania histologiczne wycinków tetnicy piersiowej wewnetrznej, zły odpiszczelowej wielkiej i aorty pobranych w czasie operacji kardiochirurgicznych.