The effect of repeated oral doses of lornoxicam on antipyrine elimination in normal human volunteers.
Treatment with lornoxicam 4 mg twice daily for 14 d did not produce any change in salivary antipyrine elimination in 11 of 12 healthy volunteers. Anomalous results in one subject are presented and discussed.
Department of Clinical Pharmacology, St. Bartholomew's Hospital, London, UK.
M
M
Ravic
A
A
Johnston
P
P
Turner
F
F
Takacs
D E
DE
Rosenow
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage* / Q000494:pharmacology; D000983:Antipyrine / Q000493:pharmacokinetics*; D005260:Female; D006801:Humans; D008297:Male; D010894:Piroxicam / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D012463:Saliva / Q000737:chemistry
D000894:Anti-Inflammatory Agents, Non-Steroidal; D010894:Piroxicam; C059451:lornoxicam; D000983:Antipyrine