CA 125 is released by human amnion cells in culture.
CA 125 was measured in the medium of human amnion cells in primary culture after confluence. The antigen accumulated as a function of time with a median value of 1897 U/mg protein after 7 days in culture. CA 125 was detectable by immunoperoxidase staining in the cells, which supports the possibility that amnion cells play a role as a source of the CA 125 found in the amniotic fluid.
Institute of Gynecology and Obstetrics, University of Perugia, Italy.
A
A
Barbati
M M
MM
Anceschi
L
L
Broccucci
E V
EV
Cosmi
D000650:Amnion / Q000166:cytology / Q000276:immunology*; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000276:immunology*; D002478:Cells, Cultured; D003470:Culture Media; D006801:Humans; D007124:Immunoenzyme Techniques; D013194:Staining and Labeling
D015295:Antigens, Tumor-Associated, Carbohydrate; D003470:Culture Media