Short-term effect of glutamine on the incorporation of glucose-carbon into nucleic acids in Ehrlich ascites tumour cells.
A slight but significant short-term incorporation (15 and 60 min) of glucose-carbon into DNA and RNA was detected in Ehrlich ascites tumour cells incubated in the presence of labelled glucose (5 mM). Glutamine (0.5 mM) increased the incorporation of glucose but did not modify the glycolytic flux.
Laboratorio de Bioquímica, Facultad de Ciencias, Universidad de Málaga, Spain.
M A
MA
Medina
J M
JM
Carrascosa
I
I
Núñez de Castro
D000818:Animals; D002244:Carbon / Q000378:metabolism*; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy / Q000378:metabolism*; D004247:DNA / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism*; D005973:Glutamine / Q000494:pharmacology*; D012313:RNA / Q000378:metabolism*
D005973:Glutamine; D012313:RNA; D002244:Carbon; D004247:DNA; D005947:Glucose