Renal norepinephrine content decreases after chronic flow probe implantation.
Electromagnetic flow probes were chronically implanted around the left renal artery in 6 female beagle dogs. 3-10 months after implantation, renal cortex norepinephrine contents of right and left kidneys were compared (liquid chromatography). In 4 out of the 6 dogs investigated 3-6 months after implantation, the norepinephrine content of the left kidney was reduced by 27-72%. In 2 dogs investigated 7 and 10 months after implantation, the difference between left and right kidney was not significant. These findings should be taken into consideration when interpreting results from chronically instrumented kidneys.
Institute of Radiology, Free University, Berlin, FRG.
G
G
Kaczmarczyk
M
M
Langer
G
G
Schulze
D000818:Animals; D003714:Denervation; D004285:Dogs; D005260:Female; D007668:Kidney / Q000294:innervation / Q000378:metabolism*; D007672:Kidney Cortex / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism*; D019736:Prostheses and Implants; D012077:Renal Artery; D012079:Renal Circulation; D012212:Rheology
D009638:Norepinephrine