Autometallography used as a histochemical indicator of lysosome function in cultured cells.
The present paper suggests the autometallographic demonstration of intralysosomal silver as a sensitive tool for the detection of subtile toxic effects in cell cultures, the method is suggested to primarily detect lysosomal damage.
University Department of Endocrinology, Aarhus County Hospital, Denmark.
J
J
Rungby
G
G
Danscher
M
M
Christensen
S
S
Ellermann-Eriksen
S C
SC
Mogensen
D000818:Animals; D002478:Cells, Cultured; D064420:Drug-Related Side Effects and Adverse Reactions; D008247:Lysosomes / Q000187:drug effects / Q000502:physiology* / Q000648:ultrastructure; D051379:Mice; D012834:Silver; D013194:Staining and Labeling
D012834:Silver