B cells from bovine leukemia virus- (BLV) infected sheep with hematological disorders express the CD5 T cell marker.
Though peripheral blood B cells from healthy sheep were known to be devoid of the CD5 T cell marker, it appears from our study that most B cells from bovine leukemia virus- (BLV) infected sheep with hematological disorders express both the CD5 marker and surface IgM. The possible meaning of this T cell marker expression on B cells from BLV-infected sheep is briefly discussed.
Letesson
J J
JJ
Microbiology and Immunology Unit, Universite Notre Dame de la Paix Namur, Belgium.
Mager
A
A
Mammerickx
M
M
Burny
A
A
Depelchin
A
A
D000818:Animals; D000943:Antigens, Differentiation / Q000032:analysis*; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis*; D001402:B-Lymphocytes / Q000276:immunology*; D018956:CD5 Antigens; D005455:Fluorescent Antibody Technique; D007075:Immunoglobulin M / Q000032:analysis; D001909:Leukemia Virus, Bovine; D007942:Leukemia, Experimental / Q000276:immunology*; D012756:Sheep
D000943:Antigens, Differentiation; D000945:Antigens, Differentiation, T-Lymphocyte; D018956:CD5 Antigens; D007075:Immunoglobulin M