Evaluating the effects of chemical exposures on adaptive functioning.
1. Although morphological and classical toxicological data have typically served as criteria for judging the effects of chemicals on the nervous system, there has been increasing interest in the use of behavioral end-points for examining the adverse effects of chemicals on nervous system function. 2. The present paper describes the current use of behavioral methods in neurotoxicity assessment and surveys some of the recent developments in the use of specialized methods for examining motor, sensory and cognitive changes following chemical exposures.
Medical Biological Laboratory TNO, Rijswijk, The Netherlands.
B M
BM
Kulig
D000222:Adaptation, Physiological / Q000187:drug effects*; D000818:Animals; D003071:Cognition / Q000187:drug effects; D004353:Drug Evaluation, Preclinical / Q000379:methods; D004785:Environmental Pollutants / Q000633:toxicity*; D009420:Nervous System / Q000187:drug effects*; D011597:Psychomotor Performance / Q000187:drug effects
D004785:Environmental Pollutants