A Swedish fatal case of nephropathia epidemica.
A previously healthy 55-year-old man with nephropathia epidemica (NE) developed disseminated intravascular coagulation, anuria and shock and died on day 6 of his disease. By use of indirect immunofluorescence technique and ELISA, specific serum IgM antibodies against Puumala virus could be detected, thus confirming the clinical diagnosis. This case demonstrates that NE in Scandinavia is a potentially lethal disease.
Linderholm
M
M
Department of Infectious Diseases, University of Umeå, Sweden.
Settergren
B
B
Ahlm
C
C
Burman
L A
LA
Träff
S
S
Bäcklund
U
U
Juto
P
P
D000914:Antibodies, Viral / Q000097:blood; D001002:Anuria / Q000209:etiology; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D004797:Enzyme-Linked Immunosorbent Assay; D005455:Fluorescent Antibody Technique; D006476:Orthohantavirus / Q000276:immunology / Q000302:isolation & purification*; D006480:Hemorrhagic Fever with Renal Syndrome / Q000150:complications / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008875:Middle Aged
D000914:Antibodies, Viral; D007075:Immunoglobulin M