Successful treatment of cervical pregnancy with oral etoposide.
Cervical ectopic pregnancy is an uncommon entity associated with significant morbidity and devastating effects on future fertility. A woman with a cervical gestation with quantitative serum beta-hCG levels higher than 46,000 mIU/mL and fetal cardiac activity on ultrasound was treated successfully with one course of oral etoposide, a fetocidal agent, which avoided operative intervention and preserved the patient's fertility.
Segna
R A
RA
Department of Obstetrics and Gynecology, Naval Hospital San Diego, California.
Mitchell
D R
DR
Misas
J E
JE
D000019:Abortifacient Agents; D000284:Administration, Oral; D000328:Adult; D002584:Cervix Uteri; D006063:Chorionic Gonadotropin / Q000097:blood; D018997:Chorionic Gonadotropin, beta Subunit, Human; D005047:Etoposide / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D010446:Peptide Fragments / Q000097:blood; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000188:drug therapy*
D000019:Abortifacient Agents; D006063:Chorionic Gonadotropin; D018997:Chorionic Gonadotropin, beta Subunit, Human; D010446:Peptide Fragments; D005047:Etoposide