[Studies of the immunostimulating properties of lipopolysaccharides and dextran sulfate based on a model of radiogenic immunodepression].
At a model of initial immunoresponse of mice to sheep erythrocytes the immunostimulating activity of lipopolysaccharide (LPS) and dextransulphate (DS) was tested. It was shown, that suppression of the immunosystem after influence of radiation can be compensated successfully by application of lipopolysaccharide and dextransulphate. The prophylactic application of these preparation is more ineffective.
Prokofjev
S A
SA
2. Moskauer Medizinisches Institut, UdSSR.
Perelygin
N L
NL
Dmitrijeva
N B
NB
Markina
E V
EV
Utesev
B S
BS
D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects / Q000528:radiation effects*; D016264:Dextran Sulfate; D003911:Dextrans / Q000494:pharmacology*; D008070:Lipopolysaccharides / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA
D000276:Adjuvants, Immunologic; D003911:Dextrans; D008070:Lipopolysaccharides; D016264:Dextran Sulfate
Untersuchungen der immunstimulierenden Eigenschaften von Lipopolysacchariden und Dextransulfat an einem Modell der radiogenen Immundepression.