[Clinical notes about methylprednisolone pulse-therapy in patients with rheumatoid arthritis].
From the analysis of literature and first-hand data on methylprednisolone pulse-therapy for rheumatoid arthritis (RA) the conclusion is made that such therapy produces a rapid and pronounced though short-term effect on the disease activity. It fails to stop RA progression. A case of two-wave effect is attributed to restoration of target cell sensitivity to chrysotherapy.
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D018501:Antirheumatic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000503:physiopathology; D004112:Dimercaprol / Q000008:administration & dosage / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D050607:Organogold Compounds; D009942:Organometallic Compounds / Q000008:administration & dosage / Q000627:therapeutic use; D020005:Propanols; D012460:Sulfasalazine / Q000008:administration & dosage / Q000627:therapeutic use; D013438:Sulfhydryl Compounds
D018501:Antirheumatic Agents; D050607:Organogold Compounds; D009942:Organometallic Compounds; D020005:Propanols; D013438:Sulfhydryl Compounds; D004112:Dimercaprol; D012460:Sulfasalazine; C013394:aurotioprol; D008775:Methylprednisolone
Klinicheskie zametki o pul's-terapii metilprednizolonom u bolnykh revmatoidnym artritom.