Langerhans' cell histiocytosis in an adult.
A woman with typical skin lesions of histiocytosis X is reported. Electron microscopic and immunohistochemical investigations revealed a large number of markedly long Birbeck Langerhans' cell granulae. During treatment with Interferon alpha -2b, the patient developed infarctus cerebri and died.
Department of Dermatology, Karolinska Hospital, Stockholm, Sweden.
B
B
Lindelöf
B
B
Forslind
M
M
Hilliges
O
O
Johansson
L
L
Aström
D000328:Adult; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000473:pathology*; D006801:Humans; D012867:Skin / Q000648:ultrastructure; D012871:Skin Diseases / Q000473:pathology*