Toxicokinetics of xenobiotics in zebrafish--comparison between tap and river water.
1. Uptake and elimination of lindane, 3,4-dichloroaniline, phenol and 4-nitrophenol by the zebrafish Brachydanio rerio were investigated in tap water and in water of the river Rhine. 2. The differences in bioconcentration of chemicals between the two water types did not exceed a factor of 2.5. 3. Elimination kinetics were comparable in tap and river water. 4. It can be concluded that water of the river Rhine does not influence the kinetics of the investigated xenobiotics.
Department of Zoology, Johannes Gutenberg University, Mainz, F.R.G.
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Ensenbach
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Nagel
D000818:Animals; D005618:Fresh Water / Q000032:analysis*; D013329:Structure-Activity Relationship; D014874:Water Pollutants, Chemical / Q000493:pharmacokinetics* / Q000633:toxicity; D014881:Water Supply / Q000032:analysis*; D015262:Xenobiotics / Q000493:pharmacokinetics* / Q000633:toxicity; D015027:Zebrafish / Q000378:metabolism*
D014874:Water Pollutants, Chemical; D015262:Xenobiotics