Myofibroblastoma of the tongue. An immunohistochemical, ultrastructural, and flow cytometric study.
A case of myofibroblastoma arising in the tongue of a 77-year-old man is described. The patient presented with a submucosal tongue mass without other associated symptoms. The tumor was 2 cm in diameter, well circumscribed, and composed of uniform spindle cells arranged in fascicles. Electron microscopic examination and immunohistochemistry demonstrated a myofibroblastic origin for the tumor cells. DNA flow cytometric analysis showed a diploid DNA content of this tumor. To the authors' knowledge, this is the first report of myofibroblastoma occurring in the tongue.
Sahin
A A
AA
Department of Pathology, University of Texas, M. D. Anderson Cancer Center, Houston 77030.
Ro
J Y
JY
Ordoñez
N G
NG
Luna
M A
MA
el-Naggar
A K
AK
Goepfert
H
H
Ayala
A G
AG
D000199:Actins / Q000378:metabolism; D000368:Aged; D003094:Collagen / Q000378:metabolism; D003893:Desmin / Q000378:metabolism; D005434:Flow Cytometry; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000378:metabolism; D007889:Leiomyoma / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D009418:S100 Proteins / Q000378:metabolism; D014062:Tongue Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure
D000199:Actins; D003893:Desmin; D009418:S100 Proteins; D007633:Keratins; D003094:Collagen