[Near infrared spectrophotometry--a non-invasive, continuous method for monitoring of cerebral status in newborn infants].
Hypoxic-ischaemic injury to the brain is the commonest cause of permanent neurodevelopmental disability in the very preterm and other children who survive after neonatal intensive care. Non-invasive techniques are therefore needed to examine the mechanisms of damage to the brain. Near infrared spectroscopy provides continuous cot-side information about cerebral oxygenation and metabolism in sick preterm infants by measurements of oxyhaemoglobin, deoxyhaemoglobin and oxidized cytokrom aa3. The cytokrome aa3 signal may, however, be artifactual due to interference from oxyhaemoglobin. Future investigations may clarify this problem.
Rigshospitalet, København, Neonatalafdelingen GN.
L
L
Skov
O
O
Pryds
B
B
Friis-Hansen
D001925:Brain Damage, Chronic / Q000517:prevention & control; D002545:Brain Ischemia / Q000150:complications / Q000000981:diagnostic imaging*; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D002534:Hypoxia, Brain / Q000150:complications / Q000000981:diagnostic imaging*; D007231:Infant, Newborn; D011859:Radiography; D013055:Spectrophotometry, Infrared / Q000379:methods*
Naer-infrarød spektrofotometri--en ikke-invasiv, kontinuerlig metode til monitorering af den cerebrale tilstand hos nyfødte.