Saliva and salivary gland alterations in HIV infection.
HIV-1 infection may involve saliva and the salivary glands. The virus may be recovered from the mouth and anti-viral antibodies are found in saliva. Salivary dysfunction after infection ranges from xerostomia to a Sjogren's syndrome-like condition with persistent glandular enlargement and marked secretory hypofunction.
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Investigations Section, NIDR, NIH, Bethesda, Md 20892.
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000998:Antiviral Agents / Q000378:metabolism; D016516:CD4-CD8 Ratio; D015496:CD4-Positive T-Lymphocytes; D015497:HIV-1 / Q000302:isolation & purification*; D006801:Humans; D012463:Saliva / Q000737:chemistry / Q000382:microbiology* / Q000502:physiology; D012466:Salivary Gland Diseases / Q000150:complications* / Q000382:microbiology / Q000503:physiopathology; D012471:Salivary Proteins and Peptides; D014987:Xerostomia / Q000150:complications
D000998:Antiviral Agents; D012471:Salivary Proteins and Peptides