[Effect of adrenergic beta blockers on hemodynamics, diastolic relaxation and distensibility of left-ventricular myocardium in patients with ischemic heart disease].
Altogether 32 patients were investigated by catheterization of the left ventricular cavity with volume loading of 76% solution of verographin++ administered at 0.65 ml per kg body mass. beta-blockade with preliminary i.v. administration of 5 mg obsidan or 10 mg cordanum was shown to improve myocardial diastolic function as a result of improved myocardial distensibility in CHD patients.
Moroz
V A
VA
Gladchenko
A R
AR
Latoguz
I K
IK
Khimenko
P L
PL
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000328:Adult; D003327:Coronary Disease / Q000188:drug therapy* / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D007223:Infant; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects* / Q000502:physiology; D011412:Propanolamines / Q000627:therapeutic use*; D011433:Propranolol / Q000627:therapeutic use*; D016277:Ventricular Function, Left / Q000187:drug effects* / Q000502:physiology
D000319:Adrenergic beta-Antagonists; D011412:Propanolamines; C011550:talinolol; D011433:Propranolol
Vliianie adrenoblokatorov na gemodinamiku, diastolicheskoe rasslablenie i rastiazhimost' miokarda levogo zheludochka u bol'nykh ishemicheskoĭ bolezn'iu serdtsa.