[The effect of duodenal exclusion on the cellular endocrine adaptation of the duodenum after performing an antrectomy. An experimental study in the rat].
We present an experimental study in rats with the aim to value the adaptative variations over the duodenal gastrin and somatostatin cell producing populations after antrectomy and gastrojejunostomy. 30 animals were distributed into two groups of 15 animals each. Group 1 rats underwent antrectomy and gastrojejunostomy, the animals of group 2 were considered as a controls. The results obtained show that after antrectomy and gastrojejunostomy an increase of gastrin producing cells is produced as well as decrease of somatostatin producing cells, both figures are statistically significant, concluding that the duodenum is able to supply the gastric antrum in gastrin production while the duodenal somatostatin cell producing population is negative influenced by the absence of alimentary stimuli and gastric secretions.
Servicio de Cirugía General, Hospital General de Mollet.
A
A
Puigdollers Pérez
F
F
Pérez Bote
E
E
Castell Friguls
M
M
Armengol Carrasco
B
B
Oller Sales
J
J
Puey Bellosta
R
R
Bordes Prats
J
J
Segura Movellán
J A
JA
Salva Lacombe
D000222:Adaptation, Physiological; D000714:Anastomosis, Surgical; D000818:Animals; D004386:Duodenum / Q000166:cytology / Q000502:physiology*; D004702:Endocrine Glands / Q000166:cytology / Q000502:physiology*; D005743:Gastrectomy; D005755:Gastrins / Q000378:metabolism; D007583:Jejunum / Q000601:surgery; D008297:Male; D011706:Pyloric Antrum / Q000601:surgery; D051381:Rats; D011919:Rats, Inbred Strains; D013004:Somatostatin / Q000378:metabolism
D005755:Gastrins; D013004:Somatostatin
Influencia de la exclusión duodenal en la adaptación celular endocrina del duodeno tras la práctica de una antrectomía. Estudio experimental en la rata.