CD5 positivity on peripheral blood B lymphocytes in patients with primary Sjögren's syndrome.
The increased number of the CD5+ (Leu 1) B cells in 9 of 17 patients with primary Sjögren's syndrome (SS) were found in this study. The percentage of CD5+ B cells that demonstrated an increased number of these cells was more than 45% in patients with pSS, and the normal level 26.3 +/- 8.8% in control subjects. The ratio of the CD5+ B cells was higher if the pSS was in the active stage.
3rd Department of Medicine, University Medical School, Debrecen, Hungary.
M
M
Zeher
P
P
Surányi
G
G
Szegedi
D015703:Antigens, CD / Q000032:analysis*; D000943:Antigens, Differentiation / Q000032:analysis*; D001327:Autoimmune Diseases / Q000150:complications / Q000276:immunology* / Q000473:pathology; D001402:B-Lymphocytes / Q000276:immunology* / Q000473:pathology; D018956:CD5 Antigens; D005260:Female; D015432:Glomerulonephritis, Membranoproliferative / Q000209:etiology / Q000276:immunology; D006801:Humans; D008223:Lymphoma / Q000209:etiology; D012859:Sjogren's Syndrome / Q000150:complications / Q000276:immunology* / Q000473:pathology
D015703:Antigens, CD; D000943:Antigens, Differentiation; D018956:CD5 Antigens