Biochemical properties of vascular endothelial cells.
Present knowledge in the field of vascular endothelial cells is reviewed. The role of endothelial cells in the synthesis of matrix proteins and glycosaminoglycans is described. Endothelial cells play a considerable role in the processes of coagulation and fibrinolysis. They also interact with neurotransmitters and vasomotoric substances, and participate in inflammation and immunological responses. They produce several different growth factors. Their role in lipoprotein metabolism is of special importance to research into atherosclerosis.
Institute for Surgical Research, University of Oslo, Norway.
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D000818:Animals; D000938:Antigen-Presenting Cells / Q000276:immunology; D001777:Blood Coagulation / Q000502:physiology; D002478:Cells, Cultured; D003176:Complement C3 / Q000096:biosynthesis; D004730:Endothelium, Vascular / Q000166:cytology / Q000378:metabolism*; D016326:Extracellular Matrix Proteins / Q000096:biosynthesis; D005342:Fibrinolysis / Q000502:physiology; D006025:Glycosaminoglycans / Q000096:biosynthesis; D006133:Growth Substances / Q000096:biosynthesis; D006801:Humans; D007249:Inflammation; D008074:Lipoproteins / Q000378:metabolism; D018377:Neurotransmitter Agents / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000378:metabolism; D014666:Vasomotor System / Q000502:physiology
D003176:Complement C3; D016326:Extracellular Matrix Proteins; D006025:Glycosaminoglycans; D006133:Growth Substances; D008074:Lipoproteins; D018377:Neurotransmitter Agents; D011956:Receptors, Cell Surface