[Fibrin glue and tetracycline pleurodesis in recurrent malignant pleural effusions. A randomized comparative study].
In a prospective randomized study the effect of pleurodesis using fibrin-glue was compared with pleurodesis using tetracycline in the management of malignant pleural effusions. Intrapleural therapy with fibrin-glue was significantly more effective concerning long-term results as relapse of pleural effusion and improvement of lung function just as time of draining pleural effusion and pain during the application of fibrin glue/tetracycline. Thus, intracavitary therapy with fibrin glue may be recommended in the control of malignant pleural effusions.
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Abteilung für Pneumologie der Medizinischen Hochschule Hannover.
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D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000503:physiopathology*; D010166:Palliative Care / Q000379:methods*; D010994:Pleura / Q000187:drug effects; D010996:Pleural Effusion / Q000628:therapy*; D013752:Tetracycline / Q000008:administration & dosage*
D015718:Fibrin Tissue Adhesive; D013752:Tetracycline
Fibrinkleber- und Tetracyclinpleurodese bei rezidivierenden malignen Pleuraergüssen. Eine randomisierte Vergleichsuntersuchung.