[Tetrazepam in the treatment of painful muscle spasms].
The aim of the study was to examine myorelaxant and analgetic effects of tetrazepam using double-blind controlled random tests. The study comprised two groups of patients with 30 subjects in each with reflex muscle spasms in the lumbar and cervical spine. One group was treated with a nonsteroid analgetic and the another one with the combination of tetrazepam and a nonsteroid analgetic. The treatment lasted 15 days and the assessment using the standardized, graded scale was performed 0, 7 and 15 days after the onset of the treatment. More hematologic and biochemical parameters were analysed both at the beginning and completion of the treatment. The results of the study have shown that the combination of nonsteroid analgetics and tetrazepam achieved better and faster effects on pain and muscle spasms compared to nonsteroid analgetics with no significant side effects.
Vojnomedicinska akademija, Klinika za neurologiju.
A
A
Jovicić
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V
Ivanisević
D000328:Adult; D014151:Anti-Anxiety Agents / Q000627:therapeutic use*; D001569:Benzodiazepines; D001570:Benzodiazepinones / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007052:Ibuprofen / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009128:Muscle Spasticity / Q000188:drug therapy*
D014151:Anti-Anxiety Agents; D001570:Benzodiazepinones; D001569:Benzodiazepines; C005245:tetrazepam; D007052:Ibuprofen
Primena tetrazepama u lecenju bolnih misićnih spazama.