[Histological and histochemical changes in the neck muscles of spontaneously occurring scoliosis in a special strain of Japanese quail, SQOHM].
A strain of Japanese quail, SQOHM, is known as a model of idiopathic scoliosis in humans. It shows hereditary scoliotic deformities occurring in the cervical region. Histological, histochemical and serological studies were performed in 51 scoliotic and 109 non-scoliotic quail. Histological study revealed internal nuclei and tiny groups of small fibers in the neck muscles. The incidence of these, however, was only 19% in the scoliotic and 7% in the non-scoliotic quail. Histochemical observation with adenosine triphosphatase, phosphorylase and succinic dehydrogenase stains was made on the dorsal neck muscles. An increase in the number of beta-fibers, and a decrease in the number and hyperplasia of alpha-fibers were observed on the concave side of the scoliosis. The increase in number of beta-fibers on the concave side can play a role in promoting the deformity was suggested.
Department of Orthopaedic Surgery, Keio University, School of Medicine, Tokyo, Japan.
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Nakai
D000251:Adenosine Triphosphatases / Q000097:blood; D000818:Animals; D003370:Coturnix / Q000235:genetics; D003402:Creatine Kinase / Q000097:blood; D004195:Disease Models, Animal; D005260:Female; D008297:Male; D009132:Muscles / Q000473:pathology*; D009334:Neck Muscles / Q000473:pathology*; D012600:Scoliosis / Q000201:enzymology / Q000473:pathology*; D013194:Staining and Labeling; D013385:Succinate Dehydrogenase / Q000097:blood
D013385:Succinate Dehydrogenase; D003402:Creatine Kinase; D000251:Adenosine Triphosphatases