Increased plasma norepinephrine in psoriasis.
Free plasma catecholamines were measured by means of a standardized HPLC method in 50 adult patients with psoriasis and in 18 healthy volunteers. The concentrations of circulating norepinephrine were significantly higher in the psoriasis group (p less than 0.005); by contrast only slight differences were found in the epinephrine and dopamine concentrations. The possible mechanisms leading to these changes are discussed.
Research Department, Spezialklinik Neukirchen, West Germany.
G
G
Ionescu
R
R
Kiehl
D000293:Adolescent; D000328:Adult; D002851:Chromatography, High Pressure Liquid; D004298:Dopamine / Q000097:blood; D004837:Epinephrine / Q000097:blood; D006801:Humans; D008875:Middle Aged; D009638:Norepinephrine / Q000097:blood*; D011565:Psoriasis / Q000097:blood*
D004298:Dopamine; D009638:Norepinephrine; D004837:Epinephrine