Renal norepinephrine content decreases after chronic flow probe implantation.
Electromagnetic flow probes were chronically implanted around the left renal artery in 6 female beagle dogs. 3-10 months after implantation, renal cortex norepinephrine contents of right and left kidneys were compared (liquid chromatography). In 4 out of the 6 dogs investigated 3-6 months after implantation, the norepinephrine content of the left kidney was reduced by 27-72%. In 2 dogs investigated 7 and 10 months after implantation, the difference between left and right kidney was not significant. These findings should be taken into consideration when interpreting results from chronically instrumented kidneys.
Kaczmarczyk
G
G
Institute of Radiology, Free University, Berlin, FRG.
Langer
M
M
Schulze
G
G
D000818:Animals; D003714:Denervation; D004285:Dogs; D005260:Female; D007668:Kidney / Q000294:innervation / Q000378:metabolism*; D007672:Kidney Cortex / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism*; D019736:Prostheses and Implants; D012077:Renal Artery; D012079:Renal Circulation; D012212:Rheology
D009638:Norepinephrine