"Anemone" cell (villiform) tumor of the brain.
At age 31, the patient developed hydrocephalus secondary to a brain lesion that had been present for 12 years. A ventriculoperitoneal shunt was performed, but a stereotactic biopsy did not establish a definitive diagnosis at that time. At age 34 the patient experienced spontaneous intratumoral and ventricular hemorrhage, which prompted radical surgical resection of the lesion. Histologic and immunocytochemical findings established a diagnosis of ependymoma; review of the ultrastructure of the tumor from the biopsy performed when the patient was 31 years old revealed the characteristics of an "anemone" cell neoplasm.
Department of Pathology, Toronto General Hospital, Ontario, Canada.
J H
JH
Deck
S
S
Ramjohn
I
I
Dardick
D000328:Adult; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology*; D002467:Cell Nucleus / Q000648:ultrastructure; D002543:Cerebral Hemorrhage / Q000209:etiology; D003593:Cytoplasm / Q000648:ultrastructure; D003937:Diagnosis, Differential; D004806:Ependymoma / Q000150:complications / Q000473:pathology*; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D008297:Male; D008854:Microscopy, Electron; D009418:S100 Proteins / Q000032:analysis; D014746:Vimentin / Q000032:analysis
D005904:Glial Fibrillary Acidic Protein; D009418:S100 Proteins; D014746:Vimentin; D007633:Keratins