Upper airway obstruction during nasal intermittent positive-pressure hyperventilation in sleep.
Episodes of apnoea for up to 1 min were observed in association with hypocapnia caused by passive nasal intermittent positive-pressure mechanical hyperventilation in 3 of 4 patients during sleep. Apnoea seemed to be caused by complete upper airways obstruction; we suggest that this finding was caused by active glottic closure. Avoidance of excessive hypocapnia during positive-pressure ventilation might help to avoid central-nervous-system mediated apnoeic episodes.
Rehabilitation Unit, Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium.
P
P
Delguste
G
G
Aubert-Tulkens
D O
DO
Rodenstein
D000328:Adult; D004569:Electroencephalography; D004576:Electromyography; D005260:Female; D005931:Glottis / Q000503:physiopathology; D006801:Humans; D016857:Hypocapnia / Q000209:etiology; D007385:Intermittent Positive-Pressure Ventilation / Q000009:adverse effects*; D015508:Nasal Obstruction / Q000150:complications* / Q000503:physiopathology; D012891:Sleep Apnea Syndromes / Q000209:etiology* / Q000503:physiopathology