Lower-limb vasospasm and renal failure during postoperative thromboprophylaxis. Case report.
In a 73-year-old woman with trimalleolar fracture, secondary acute ischemia of the limb and renal failure developed in association with heparin-dihydroergotamine thromboprophylaxis. Earlier cases of thromboprophylaxis-related angiospasm are briefly reviewed. The condition is infrequent, but trauma of extremities and shock are risk factors. Renal failure is rare.
Mattsson
E
E
Department of Orthopedic Surgery, Malmö General Hospital, Lund University, Sweden.
Ohlin
A
A
Balkfors
B
B
Fredin
H O
HO
Nilsson
P
P
Bergqvist
D
D
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000368:Aged; D000792:Angiography; D004087:Dihydroergotamine / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006493:Heparin / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007511:Ischemia / Q000139:chemically induced* / Q000000981:diagnostic imaging; D007866:Leg / Q000098:blood supply*; D011183:Postoperative Complications / Q000517:prevention & control*; D013035:Spasm / Q000139:chemically induced; D013924:Thrombophlebitis / Q000517:prevention & control*; D014661:Vasoconstriction / Q000187:drug effects
D004087:Dihydroergotamine; D006493:Heparin