Clastogenic activity of strontium chloride on bone marrow cells in vivo.
Oral administration of different concentrations of Strontium chloride to laboratory bred mice in vivo induced chromosomal aberrations in bone marrow cell metaphase preparations. The degree of clastogenicity was directly proportional to concentration used at 6, 12, and 24 h of treatment. Duration of treatment could only be related positively in the lower doses. The females showed greater susceptibility than the males at all concentrations used.
Department of Botany, University of Calcutta, India.
S
S
Ghosh
G
G
Talukder
A
A
Sharma
D000818:Animals; D001853:Bone Marrow / Q000648:ultrastructure*; D002869:Chromosome Aberrations; D005260:Female; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D008938:Mitosis / Q000187:drug effects; D009153:Mutagens; D013324:Strontium / Q000633:toxicity*
D009153:Mutagens; C025700:strontium chloride; D013324:Strontium