Depletion of bone marrow T-lymphocytes with an anti-CD5 monoclonal immunotoxin (ST-1 immunotoxin): effective prophylaxis for graft-versus-host disease.
Division of Hematology, Brigham and Women's Hospital, Boston, Massachusetts.
J H
JH
Antin
B E
BE
Bierer
B R
BR
Smith
E C
EC
Guinan
M M
MM
Provost
J
J
Ferrara
R M
RM
Macklis
N J
NJ
Tarbell
H
H
Blythman
C
C
Bouloux
D000293:Adolescent; D000328:Adult; D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D015703:Antigens, CD / Q000276:immunology; D000943:Antigens, Differentiation / Q000276:immunology; D001853:Bone Marrow / Q000276:immunology*; D001854:Bone Marrow Cells; D016026:Bone Marrow Transplantation / Q000276:immunology / Q000379:methods*; D018956:CD5 Antigens; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D003561:Cytarabine / Q000627:therapeutic use; D004341:Drug Evaluation; D006086:Graft vs Host Disease / Q000517:prevention & control*; D006801:Humans; D000922:Immunotoxins / Q000627:therapeutic use*; D007938:Leukemia / Q000628:therapy; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000628:therapy; D012276:Ricin / Q000627:therapeutic use*; D012307:Risk Factors; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D014916:Whole-Body Irradiation
D000911:Antibodies, Monoclonal; D015703:Antigens, CD; D000943:Antigens, Differentiation; D018956:CD5 Antigens; D000922:Immunotoxins; D003561:Cytarabine; D003520:Cyclophosphamide; D012276:Ricin