Identification of twelve new RFLP-markers on chromosome 22q11-qter.
We have previously identified and regionally localized 195 chromosome-22-specific DNA markers. We now report restriction fragment length polymorphisms detected by 9 phage markers mapped to 22q11-q12, two cosmid clones mapped to 22q12-q13 and one plasmid mapped to 22q13-qter. These markers may be useful tools for mapping disease genes such as the NF2 locus, on chromosome 22.
Department of Clinical Genetics, Karolinska Hospital, Stockholm, Sweden.
E
E
Carlbom
N
N
Sugawa
C
C
Larsson
P J
PJ
Scambler
J P
JP
Dumanski
V P
VP
Collins
M
M
Nordenskjöld
D000483:Alleles; D015139:Blotting, Southern; D002892:Chromosomes, Human, Pair 22; D003001:Cloning, Molecular; D003360:Cosmids / Q000235:genetics; D004262:DNA Restriction Enzymes / Q000378:metabolism; D005819:Genetic Markers / Q000235:genetics*; D006801:Humans; D012150:Polymorphism, Restriction Fragment Length
D005819:Genetic Markers; D004262:DNA Restriction Enzymes