Doppler umbilical velocimetry in women with polydrug abuse including cocaine.
Doppler umbilical artery velocimetry was performed in 40 chemically dependent women. The mean S/D ratio was 2.7 with 15/66 values greater than or equal to 3.0. No cases of absent or reverse end-diastolic flow were noted. The mean S/D ratio in women with positive toxicologies for cocaine use was not statistically elevated compared to women with negative screens (2.8 versus 2.7, P = 0.51). In this study an S/D ratio greater than or equal to 3.0 had a sensitivity of 40% for identifying intrauterine growth retardation with a positive predictive value of 20%.
Department of Obstetrics and Gynecology, Northwestern Medical School, Chicago, Illinois.
L S
LS
Cohen
R E
RE
Sabbagha
L G
LG
Keith
I J
IJ
Chasnoff
D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology; D003042:Cocaine; D005260:Female; D005317:Fetal Growth Retardation / Q000000981:diagnostic imaging* / Q000453:epidemiology; D006801:Humans; D007231:Infant, Newborn; D011237:Predictive Value of Tests; D011247:Pregnancy; D011248:Pregnancy Complications / Q000000981:diagnostic imaging*; D012680:Sensitivity and Specificity; D019966:Substance-Related Disorders; D014463:Ultrasonography; D014469:Umbilical Arteries / Q000000981:diagnostic imaging*
D003042:Cocaine