[Determination of placental protein 12 (insulin-like growth factor binding protein 25) in pleural effusion of various origins].
It is reported on the possible role of the radioimmunological estimation of placental protein 12 (PP 12; insulin-like growth factor binding protein 25, IGF-BP 25) in pleural effusions of patients with lung cancer, with pleural carcinosis of extrathoracal carcinomas and benign pleural diseases, respectively. There are more PP 12, IGF-BP 25-positive cases at benign diseases than at carcinomas at all. It is discussed the possible importance of PP 12, IGF-BP 25 as a binding protein of growth factor s IGF-I and -II. The clinical validity should be analysed in more detail on the basis of the estimation of more patients.
Frauenklinik Bezirkskrankenhauses Wismar.
R R
RR
Strache
H H
HH
Büttner
P
P
Göcze
D
D
Szabó
P O
PO
Willroth
V
V
Briese
I
I
Csaba
D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000378:metabolism*; D002283:Carcinoma, Bronchogenic / Q000175:diagnosis* / Q000378:metabolism; D002352:Carrier Proteins / Q000378:metabolism*; D003937:Diagnosis, Differential; D006801:Humans; D018969:Insulin-Like Growth Factor Binding Proteins; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D008875:Middle Aged; D010996:Pleural Effusion / Q000378:metabolism*; D010997:Pleural Neoplasms / Q000175:diagnosis / Q000556:secondary
D014408:Biomarkers, Tumor; D002352:Carrier Proteins; D018969:Insulin-Like Growth Factor Binding Proteins
Bestimmungen des Plazentaproteins 12 (insulin-like growth factor binding protein 25) im Pleuraerguss unterschiedlicher Genese.