The role of chest computed tomography in the diagnosis of drug-related reactions.
Computed tomography (CT) of the chest provides important information toward the diagnosis of drug-induced lung disease. CT's ability to demonstrate subtle parenchymal and pleural changes, small nodules, and adenopathy is valuable in the early detection of drug-related reactions. CT is also of value in monitoring the appearance, progression, and resolution of pulmonary damage in patients receiving potentially toxic drugs. The CT appearances of specific drug reactions are reviewed, including the spectrum of CT findings in bleomycin toxicity and amiodarone-induced lung disease.
Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, Maryland.
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Kuhlman
D000638:Amiodarone / Q000009:adverse effects; D001761:Bleomycin / Q000009:adverse effects; D004342:Drug Hypersensitivity / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D007119:Immunoblastic Lymphadenopathy / Q000139:chemically induced / Q000000981:diagnostic imaging; D008168:Lung / Q000000981:diagnostic imaging; D008171:Lung Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000009:adverse effects
D001761:Bleomycin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D000638:Amiodarone