Nomenclature of vasculitic syndromes: a historical perspective.
Since the original description of periarteritis nodosa (PAN) in 1866, the number of recognized forms of so-called idiopathic vasculitis has risen to about a dozen. Their relation to each other and their nature remain unclear, although the recent discovery of antineutrophil cytoplasmic autoantibodies (ANCA) promises a clue to the origin of at least some of them, particularly Wegener's granulomatosis (WG) and perhaps also Churg-Strauss syndrome (CSS). On the other hand, PAN appears to be a nonspecific syndrome of various etiologies.
Department of Pathology, Mount Sinai School of Medicine, New York, NY.
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D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies / Q000302:isolation & purification; D015267:Churg-Strauss Syndrome / Q000473:pathology; D014890:Granulomatosis with Polyangiitis / Q000473:pathology; D006801:Humans; D009504:Neutrophils / Q000276:immunology; D010488:Polyarteritis Nodosa / Q000473:pathology; D009626:Terminology as Topic; D014657:Vasculitis / Q000145:classification* / Q000276:immunology / Q000473:pathology
D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies