Experience with omeprazole in erosive oesophagitis.
Omeprazole is a potent, highly specific, and clinically efficacious anti-secretory agent. Current clinical data suggest that omeprazole could be a useful drug in the short-term treatment of patients with severe erosive oesophagitis resistant to standard H2-receptor antagonist therapy. The magnitude of omeprazole's eventual role in the treatment of acid secretory-related disorders will depend on the results of its expanded postmarketing clinical experience and upon resolution of concerns regarding potential adverse effects associated with long-term administration.
Robinson
M G
MG
Oklahoma Foundation for Digestive Research, Oklahoma City 73104.
Decktor
D L
DL
D004942:Esophagitis, Peptic / Q000188:drug therapy*; D006635:Histamine H2 Antagonists / Q000627:therapeutic use; D006801:Humans; D009853:Omeprazole / Q000009:adverse effects / Q000627:therapeutic use*
D006635:Histamine H2 Antagonists; D009853:Omeprazole