The effect of various avocado oils on skin collagen metabolism.
The effects of various avocado oils on collagen metabolism in skin were studied in growing rats fed diets containing 10% (w/w) of the tested oils. Rats fed the unrefined avocado oil extracted with hexane from the intact fruit, its unsaponifiables or the avocado seed oil, showed significant increases in soluble collagen content in skin, though total collagen content was not affected. The increased soluble collagen content appears to be a consequence of the inhibition of lysyl oxidase activity. The active factor was found to be present in the unrefined avocado oil and probably originated from the avocado seed, since collagen metabolism was affected only by fractions which contained lipids fraction from the seed. In comparison rats fed the refined or unrefined soybean oils showed no effects.
Department of Food Engineering and Biotechnology, Technion-Israel Institute of Technology, Haifa, Israel.
M J
MJ
Werman
S
S
Mokady
M E
ME
Nimni
I
I
Neeman
D000818:Animals; D003094:Collagen / Q000378:metabolism*; D004042:Dietary Fats, Unsaturated / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D010938:Plant Oils / Q000008:administration & dosage / Q000494:pharmacology*; D008249:Protein-Lysine 6-Oxidase / Q000037:antagonists & inhibitors; D051381:Rats; D012639:Seeds / Q000032:analysis; D012867:Skin / Q000187:drug effects / Q000378:metabolism*; D013024:Soybean Oil / Q000008:administration & dosage / Q000494:pharmacology
D004042:Dietary Fats, Unsaturated; D010938:Plant Oils; D013024:Soybean Oil; D003094:Collagen; D008249:Protein-Lysine 6-Oxidase