[Left ventricular remodeling and ischemic heart diseases. Therapeutic possibilities].
Left ventricular modeling after myocardial infarction may be modified in three ways: firstly, by limiting the infarct size; secondly, by administering ACE inhibitors: these drugs limit infarct expansion and ventricular dilatation. They reduce the prevalence of secondary left ventricular failure and, in the animal, improve the prognosis. Glyceryl trinitrate also appears to be effective. The third therapeutic option is maintaining the patency of the artery responsible for the infarction, which has a beneficial effect on ventricular remodeling. The respective therapeutic indications of these three options are still a matter of discussion.
Service de cardiologie, hôpital Bichat, Paris.
A
A
Cohen-Solal
D
D
Himbert
C
C
Paillole
F
F
Chikli
M
M
Dahan
P G
PG
Steg
J M
JM
Juliard
R
R
Gourgon
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D003327:Coronary Disease / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D015425:Myocardial Reperfusion; D014665:Vasodilator Agents / Q000627:therapeutic use*
D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000894:Anti-Inflammatory Agents, Non-Steroidal; D014665:Vasodilator Agents
Remodelage ventriculaire gauche et cardiopathies ischémiques. Possibilités thérapeutiques.