Pseudoknots: a new motif in the RNA game.
In the last few years a novel RNA folding principle called pseudoknotting has emerged. Originally discovered in noncoding regions of plant viral RNAs, pseudoknots now appear to be a widespread structural motif in a number of functionally different RNAs. These structural elements are part of tRNA-like structures and are involved in folding catalytic sites of ribozymes. They increase the efficiency of ribosomal frameshifting or can serve as specific binding sites for regulatory proteins.
Department of Biochemistry, University of Leiden, The Netherlands.
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D001483:Base Sequence; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D012313:RNA; D016337:RNA, Catalytic; D012333:RNA, Messenger; D012335:RNA, Ribosomal; D012343:RNA, Transfer
D016337:RNA, Catalytic; D012333:RNA, Messenger; D012335:RNA, Ribosomal; D012313:RNA; D012343:RNA, Transfer