Continuous epidural hydromorphone for postthoracotomy pain relief.
Forty-four patients were treated with a continuous infusion of lumbar epidural hydromorphone (0.05%) after thoracic operations. Postoperatively, visual analog pain scores were obtained. On postoperative day 1 and 2, more than 90% of the patients experienced either no pain (visual analog pain scale = 0) or mild pain (visual analog pain score = 1 to 3) at rest. The incidence of side effects (hypoventilation, pruritus, and nausea) was less than reported with other epidurally administered opioids. Continuous infusion of lumbar epidural hydromorphone produced safe, predictable analgesia after thoracotomy.
Brodsky
J B
JB
Department of Anesthesia, Stanford University School of Medicine, California.
Chaplan
S R
SR
Brose
W G
WG
Mark
J B
JB
D015360:Analgesia, Epidural; D000767:Anesthesia, Epidural; D003258:Consumer Behavior; D005260:Female; D005283:Fentanyl / Q000627:therapeutic use; D006801:Humans; D004091:Hydromorphone / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D007430:Intraoperative Care; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D011446:Prospective Studies; D013908:Thoracotomy / Q000009:adverse effects; D013997:Time Factors
D004091:Hydromorphone; D005283:Fentanyl