Serotonin and proctolin modulate the response of a stretch receptor in crayfish.
The modulatory effects of proctolin and a biogenic amine (5-hydroxytryptamine; 5-HT) have been investigated on a leg mechanoreceptor in the crayfish. Single afferent sensory units were recorded extra- and intracellularly during imposed sinusoidal movement to the receptor strand; all responses were facilitated by a bath application of proctolin and 5-HT at various concentrations (10(-9)-10(-6) M).
LNF2, CNRS, Marseille, France.
A
A
el Manira
C
C
Rossi-Durand
F
F
Clarac
D000818:Animals; D003400:Astacoidea / Q000502:physiology*; D066298:In Vitro Techniques; D008465:Mechanoreceptors / Q000187:drug effects*; D009479:Neuropeptides; D018377:Neurotransmitter Agents / Q000494:pharmacology; D009842:Oligopeptides / Q000494:pharmacology*; D009994:Osmolar Concentration; D010812:Physical Stimulation; D012701:Serotonin / Q000494:pharmacology*
D009479:Neuropeptides; D018377:Neurotransmitter Agents; D009842:Oligopeptides; D012701:Serotonin; C011536:proctolin