[Pregnancy and chronic inflammatory bowel diseases].
Chronic diseases have influence on fertility and course of pregnancy. Altogether 107 women who suffered from ulcerous colitis and Crohn's disease, respectively, were examined. The average weight and the size of the new-born after manifestation did not differ from those before the beginning of the disease. Low birth weight were observed after the medication of prednisolone and a manifestation of the ulcerous colitis during the gravidity. The ability for conception is not restricted when this disease is existing. An infertility rate being above the norm of the total population is to be found in Crohn's disease. There is no correlation to the localisation of the changes. It can be consented to a pregnancy in lacking Crohn's disease or in a mild activity of this disease. When there are moderately severe and severe attacks before the realization of the wish of having a child a dietetic, medicamentous or surgical therapy is to be recommended. The treatment with low-dosed azulfidine and corticosteroid has no influence on the development of the child. A prophylactic therapy is indicated in ulcerative colitis, an interruption is rarely to be proved. In an acute attack during the pregnancy, when the accurate diagnosis is imperative the fully effective dose in therapy is to be aspired to.
Klinik und Poliklinik für Innere Medizin, Martin-Luther-Universität Halle-Wittenberg.
W
W
Schneider
E
E
Hänert
D001724:Birth Weight; D003093:Colitis, Ulcerative / Q000628:therapy*; D003424:Crohn Disease / Q000628:therapy*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy*; D011644:Puerperal Disorders / Q000628:therapy; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D012460:Sulfasalazine / Q000008:administration & dosage
D012460:Sulfasalazine; D011239:Prednisolone
Schwangerschaft und chronisch-entzündliche Darmkrankheiten.