[Edema inhibiting effect of indenochromene derivatives from natural sources].
Experiments carried out with rats of Sprague-Dawley CFY strain have shown that indenochromene derivatives (brasilin, hematoxylin, hematein) inhibit significantly paw oedema of rats induced by carrageenin. Foot oedema produced by dextran has only decreased after application of hematein. Generalized dextran oedema, i. e. thermic oedema has significantly decreased after application of brasilin and hematoxylin. Experiments carried out with mice of CFLP strain have proved that indenochromene derivatives--even in small quantities--decrease ear oedema produced by dithranol statistically in a great extent.
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SZOTE Gyógyszerhatástani Intézet.
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D000818:Animals; D001578:Benzopyrans / Q000627:therapeutic use*; D002351:Carrageenan; D003911:Dextrans; D004487:Edema / Q000503:physiopathology / Q000517:prevention & control*; D006416:Hematoxylin / Q000031:analogs & derivatives / Q000627:therapeutic use*; D051379:Mice; D008815:Mice, Inbred Strains; D051381:Rats; D011919:Rats, Inbred Strains
D001578:Benzopyrans; D003911:Dextrans; C007915:hematein; D002351:Carrageenan; C044362:brazilin; D006416:Hematoxylin
Természetes eredetü indenokromen-származékok ödémagátló hatása.