[Restriction fragment length polymorphism of the apolipoprotein A-I gene among inhabitants of Novosibirsk].
Restriction fragments' length polymorphism in the region of apolipoprotein A-I (apo A-I) gene was investigated in Novosibirsk (Siberia, USSR) population. Correlation between PstI apo A-I alleles (2,2 kb-P1; 3,3 kb-P2) and total cholesterol, triglycerides, high density polyproteins cholesterol, and apolipoprotein A-I level was analysed. A tendency to increase in cholesterol index of atherogenicity and to decrease in high density lipoproteins cholesterol as well as apolipoprotein A-I level was shown to occur for P1P2 genotype patients.
A B
AB
Maslennikov
S P
SP
Kovalenko
E A
EA
Oteva
T A
TA
Filimonova
N P
NP
Mertvetsov
D000483:Alleles; D016632:Apolipoprotein A-I / Q000235:genetics*; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D005060:Europe; D005838:Genotype; D011110:Polymorphism, Genetic / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length; D012800:Siberia; D014280:Triglycerides / Q000097:blood; D014481:United States
D016632:Apolipoprotein A-I; D008076:Cholesterol, HDL; D014280:Triglycerides; D002784:Cholesterol
Polimorfizm dlin restriktsionnykh fragmentov gena apolipoproteina A-I sredi zhiteleĭ g. Novosibirska.