Canine leishmaniasis associated with systemic vasculitis in two dogs.
Two cases of canine leishmaniasis associated with systemic necrotizing vasculitis are described. The main macroscopic lesions were haemorrhagic in type; histopathological changes confirmed a vascular lesion affecting small arteries of several organs (skin, intestinal tract, kidney, urinary bladder, mesenteric lymph nodes, adrenal gland, myocardium, lung, eye and choroid plexus). The presence of the parasite was confirmed with a specific immunocytochemical stain. The possibility of an immunological aetiology of the vasculitis and its classification is discussed.
Pathology Department, Faculty of Veterinary Medicine, Autonomous University of Barcelona, U.A.B., Bellaterra, Spain.
M
M
Pumarola
L
L
Brevik
J
J
Badiola
A
A
Vargas
M
M
Domingo
L
L
Ferrer
D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D006470:Hemorrhage / Q000469:parasitology / Q000473:pathology / Q000662:veterinary; D007124:Immunoenzyme Techniques; D007074:Immunoglobulin G / Q000032:analysis; D007893:Leishmania donovani / Q000276:immunology / Q000302:isolation & purification; D007898:Leishmaniasis, Visceral / Q000473:pathology / Q000662:veterinary*; D010488:Polyarteritis Nodosa / Q000469:parasitology / Q000662:veterinary*
D000913:Antibodies, Protozoan; D007074:Immunoglobulin G