[Changes in various serum protein levels between acute and convalescent phases in patients with respiratory infections].
We determined serum levels of alpha 1-antitrypsin, alpha 1-acid glycoprotein, ceruloplasmin, haptoglobin, alpha 2-HS glycoprotein, C3 and fibronectin in 22 patients with acute pneumonia, 10 patients with mycoplasma pneumonia and 8 patients with exacerbation of chronic bronchitis at both acute and convalescent phases to clarify whether levels of these proteins change with inflammation. Serum levels of alpha 1-antitrypsin, alpha 1-acid glycoprotein, ceruloplasmin, haptoglobin and C3 in the patients in the acute phase were significantly higher than that in the patients in the convalescent phase. The serum level of fibronectin in the patients in the acute phase was significantly lower than that in the patients in convalescent phase. The serum level of alpha 2HS glycoprotein remained unchanged.
Department of Clinical Pathology, Hiroshima University, School of Medicine, Japan.
M
M
Takaishi
K
K
Sadamoto
S
S
Takami
S
S
Ishioka
S
S
Hozawa
M
M
Yamakido
D000209:Acute-Phase Proteins / Q000378:metabolism*; D000210:Acute-Phase Reaction / Q000097:blood*; D001991:Bronchitis / Q000097:blood*; D005353:Fibronectins / Q000097:blood; D006023:Glycoproteins / Q000097:blood; D006801:Humans; D007249:Inflammation / Q000097:blood*; D011014:Pneumonia / Q000097:blood*; D011019:Pneumonia, Mycoplasma / Q000097:blood; D000515:alpha 1-Antitrypsin / Q000378:metabolism
D000209:Acute-Phase Proteins; D005353:Fibronectins; D006023:Glycoproteins; D000515:alpha 1-Antitrypsin