Compounds affecting mosquito oviposition: structure-activity relationships and concentration effects.
Evidence is reviewed for a dose-dependent reversal of response in mosquito oviposition, in which a compound that attracts or stimulates oviposition may repel or deter oviposition at a higher concentration. On the basis of a review of structure-activity relationships in compounds affecting mosquito oviposition, 5 hexanoic acid derivatives were selected for field tests with Aedes aegypti ssp. formosus in Kenya. Egg counts were increased most by methyl hexanoic acid and 5-methyl-2-hexanone, and the presence or absence of a methyl branch affected egg numbers more than the difference between a carbonyl and a carboxylic acid functional group. Hexanoic acid increased egg counts at low release rates, but decreased them at higher release rates.
Gonville College, Cambridge, England.
J C
JC
Knight
S A
SA
Corbet
D000818:Animals; D002208:Caproates / Q000737:chemistry / Q000494:pharmacology*; D009033:Culicidae / Q000033:anatomy & histology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D010058:Oviposition / Q000187:drug effects*; D010063:Ovum
D002208:Caproates; C060775:methyl caproate