Bilateral familial carotid body paragangliomas. Report of a case with DNA flow cytometric and cytogenetic analyses.
A case study of bilateral familial carotid body paragangliomas with DNA flow cytometric and cytogenetic analyses is presented. Analysis of tumor cell nuclear DNA content by flow cytometry revealed aneuploid cell populations in both tumors. Standard cytogenetic analysis (Giemsa-banding technique used) of the right carotid body paraganglioma showed no evidence of numerical or structural abnormalities. We describe parameters currently used to "predict" biological behavior in these tumors.
Department of Pathology, University of Arkansas for Medical Sciences, Little Rock.
J K
JK
Granger
H Y
HY
Houn
D000328:Adult; D002345:Carotid Body Tumor / Q000175:diagnosis / Q000235:genetics / Q000473:pathology*; D004273:DNA, Neoplasm / Q000032:analysis; D005434:Flow Cytometry; D006801:Humans; D007150:Immunohistochemistry; D007621:Karyotyping; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D011003:Ploidies; D013194:Staining and Labeling
D004273:DNA, Neoplasm