[Dynamics of thyrostimulating immunoglobulin levels during treatment of diffuse toxic goiter].
Twenty-five patients with diffuse toxic goiter, investigated at various time of mercazolyl therapy, demonstrated the presence of thyrostimulating immunoglobulins in 100% before treatment, in 91% after 6 months and in 50% after 12 months of treatment. Specific therapy reduced considerably not only the frequency of detection but also the activity of thyrostimulating immunoglobulins. Clinical and hormonal remission of disease did not always coincide with immunological remission.
Sviridenko
N Iu
NIu
Mkrtukova
N A
NA
Kraĭnova
S I
SI
Nefedov
S B
SB
Kandror
V I
VI
D000293:Adolescent; D000328:Adult; D000368:Aged; D001323:Autoantibodies / Q000097:blood*; D005260:Female; D006042:Goiter / Q000097:blood / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D018828:Immunoglobulins, Thyroid-Stimulating; D008297:Male; D008713:Methimazole / Q000627:therapeutic use*; D008875:Middle Aged; D011237:Predictive Value of Tests; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D013997:Time Factors; D014284:Triiodothyronine / Q000097:blood
D001323:Autoantibodies; D018828:Immunoglobulins, Thyroid-Stimulating; D014284:Triiodothyronine; D008713:Methimazole; D013972:Thyrotropin; D013974:Thyroxine
Dinamika urovnia tireostimuliruiushchikh immunoglobulinov v protsesse lecheniia diffuznogo toksicheskogo zoba.