[An immunohistochemical study of placenta-specific alpha 2-microglobulin in human ontogeny].
Tissues of adult man and fetus were studied by indirect immunoperoxidase technique using affinity-purified antibodies against placenta-specific alpha 2-microglobulin (APM-2). APM-2 proved to be synthesized mucous membrane cells of uterus during secretory phase of the menstrual cycle. APM-2 was also found in atretic follicle of fertile woman ovary as well as in I order oocytes from the fetus ovary (26 weeks). In men APM-2 is synthesized in seminal vesicles. APM-2 was found both in cytotrophoblast and in syncytiotrophoblast as shown by study of chorionic villi.
Tatarinov
Iu S
IuS
Tsareva
T Iu
TIu
Pugachev
K K
KK
Terent'ev
A A
AA
Shimbireva
I B
IB
D000328:Adult; D000510:Alpha-Globulins / Q000032:analysis / Q000276:immunology / Q000378:metabolism*; D004717:Endometrium / Q000378:metabolism; D005260:Female; D005333:Fetus; D005496:Follicular Atresia / Q000502:physiology; D006801:Humans; D007124:Immunoenzyme Techniques; D007150:Immunohistochemistry; D008297:Male; D009865:Oocytes / Q000378:metabolism; D012669:Seminal Vesicles / Q000378:metabolism; D014327:Trophoblasts / Q000378:metabolism
D000510:Alpha-Globulins; C025500:alpha(2)-microglobulin
Immunogistokhimicheskoe issledovanie spetsificheskogo dlia platsenty al'fa 2-mikroglobulina v ontogeneze cheloveka.