[Allogeneic bone marrow transplantation in the treatment of leukemia: analysis of 10 cases].
Ten leukemic patients were treated with allogeneic bone marrow transplantation (BMT). The diagnosis were ANLL in 6 cases, CML in 3 and ALL in one. Pretransplant immuno suppressive measures including total body irradiation cyclophosphamide and daunorubicin were given. All the patients were infused with health stem cell preparation, so that the hemopoietic function was restored. Graft versus-host disease of grade I to II was present in 5 of the patients. Leukemia recurred 76 days after BMT in one patient who received the procedure during a relapse of the disease, while in the remaining 9 patients disease-free survival from 1 to 23 months has been observed.
Department of Hematology, Affiliated 307 Hospital.
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LX
Cao
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TQ
Zeng
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Chen
D000293:Adolescent; D000328:Adult; D016026:Bone Marrow Transplantation; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D003630:Daunorubicin / Q000627:therapeutic use; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000601:surgery* / Q000628:therapy; D015470:Leukemia, Myeloid, Acute / Q000601:surgery* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D014916:Whole-Body Irradiation
D003520:Cyclophosphamide; D003630:Daunorubicin