The cannabinoid receptor: biochemical, anatomical and behavioral characterization.
The actions of the active principle of marihuana, delta 9-tetrahydrocannabinol, are mimicked by synthetic cannabinoid agonists showing high potency and enantio-selectivity in behavioral assays. These drugs have been used to characterize cannabinoid receptor binding, biochemistry and pharmacology, leading to a better understanding of the effects of cannabinoids in the CNS of humans and experimental animals.
Department of Pharmacology, St Louis University School of Medicine, MO 63104.
A C
AC
Howlett
M
M
Bidaut-Russell
W A
WA
Devane
L S
LS
Melvin
M R
MR
Johnson
M
M
Herkenham
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D001921:Brain / Q000378:metabolism*; D002186:Cannabinoids / Q000378:metabolism* / Q000494:pharmacology; D006801:Humans; D051381:Rats; D043882:Receptors, Cannabinoid; D011955:Receptors, Drug / Q000378:metabolism*
D002186:Cannabinoids; D043882:Receptors, Cannabinoid; D011955:Receptors, Drug