Memory for temporal order in schizophrenia.
Memory for temporal order information was examined in patients with chronic schizophrenia using the recency discrimination task. In this task, subjects were shown a pair of previously studied words and were asked to choose which one of the two words they had seen more recently. In addition, subjects performed the Wisconsin Card Sorting Test (WCST). The results showed that schizophrenic patients differed from normal control subjects in their performance on the recency discrimination task. In addition, for schizophrenic patients, performance on the recency discrimination task was inversely related to the number of perseverative errors on the WCST. These results provide further evidence of prefrontal-type cognitive deficits in schizophrenia.
Department of Psychiatry, VA Medical Center, Washington, DC 20422.
B L
BL
Schwartz
L H
LH
Deutsch
C
C
Cohen
D
D
Warden
S I
SI
Deutsch
D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001590:Benztropine / Q000031:analogs & derivatives / Q000627:therapeutic use; D002908:Chronic Disease; D004193:Discrimination Learning / Q000187:drug effects / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D011939:Mental Recall / Q000187:drug effects / Q000502:physiology; D008875:Middle Aged; D009483:Neuropsychological Tests; D010276:Parasympatholytics; D012559:Schizophrenia / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D012565:Schizophrenic Psychology; D012691:Serial Learning / Q000187:drug effects / Q000502:physiology
D014150:Antipsychotic Agents; D010276:Parasympatholytics; D001590:Benztropine