[Is there a future for vaccines against gastrointestinal helminths?].
Vaccines against gastro-intestinal helminths have a large market potential, but they also generally have a narrow range of activity. This is a major drawback in the competition with the broad-spectrum anthelmintics and there is still a long way to go before molecular (recombinant) vaccines will appear on the market. Major problems are the induction of protective gut-mucosal immunity with subunit vaccines and the differences in genetic background within host populations, which largely determine the efficacy of vaccination. As yet the changes for vaccines against blood- and tissue parasites, comprising a number of veterinary important protozoa, seem to be better.
Bos
H J
HJ
Intervet International B.V., Boxmeer.
Schetters
T
T
D000818:Animals; D000939:Epitopes / Q000276:immunology; D006373:Helminthiasis / Q000517:prevention & control; D006374:Helminthiasis, Animal; D006376:Helminths / Q000276:immunology*; D014612:Vaccines / Q000302:isolation & purification*; D014613:Vaccines, Attenuated; D015164:Vaccines, Inactivated
D000939:Epitopes; D014612:Vaccines; D014613:Vaccines, Attenuated; D015164:Vaccines, Inactivated
Is er een toekomst voor vaccins tegen maag-darmwormen?