The human PDGF receptor alpha-subunit gene maps to chromosome 4 in close proximity to c-kit.
The gene encoding the alpha-subunit of the human platelet-derived growth factor receptor (PDGFRA) maps to band q11-q12 of chromosome 4 by in situ hybridization, which was confirmed by Southern analysis of a Chinese hamster x human cell hybrid that retains only human chromosome 4.
Gronwald
R G
RG
Department of Pathology, University of Washington, Seattle 98195.
Adler
D A
DA
Kelly
J D
JD
Disteche
C M
CM
Bowen-Pope
D F
DF
D000818:Animals; D015139:Blotting, Southern; D002874:Chromosome Mapping; D002894:Chromosomes, Human, Pair 4; D006224:Cricetinae; D006801:Humans; D006822:Hybrid Cells; D009693:Nucleic Acid Hybridization; D010982:Platelet-Derived Growth Factor; D011518:Proto-Oncogene Proteins / Q000235:genetics; D019009:Proto-Oncogene Proteins c-kit; D011956:Receptors, Cell Surface / Q000235:genetics*; D017479:Receptors, Platelet-Derived Growth Factor
D010982:Platelet-Derived Growth Factor; D011518:Proto-Oncogene Proteins; D011956:Receptors, Cell Surface; D019009:Proto-Oncogene Proteins c-kit; D017479:Receptors, Platelet-Derived Growth Factor