[The keratinocyte--a biologically active cell].
Both keratin synthesis and the formation of the horny layer are "classical" functions of human epidermal keratinocytes. In recent year a couple of interesting immunological functions of keratinocytes have been discovered. In the present review phagocytosis, production and secretion of cytokines (IL-1, IL-3, IL-6, IL-8, CSF, ECDF, IFN) and their ligands as well as the expression of selected cell surface receptors (HLA-DR, ICAM-1, Fc-gamma receptor) ligands are described.
Klinik und Poliklinik für Hautkrankheiten, Friedrich-Schiller-Universität Jena.
B
B
Knopf
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U
Wollina
D016207:Cytokines / Q000096:biosynthesis; D006801:Humans; D015603:Keratinocytes / Q000276:immunology / Q000502:physiology*; D007633:Keratins / Q000096:biosynthesis; D010587:Phagocytosis; D011947:Receptors, Antigen, B-Cell; D011971:Receptors, Immunologic
D016207:Cytokines; D011947:Receptors, Antigen, B-Cell; D011971:Receptors, Immunologic; D007633:Keratins
Der Keratinozyt--eine biologisch aktive Zelle.