Helminths, immunology and equations.
Although the immune system is becoming better characterized, it is by no means becoming easier to predict the outcome of activation given the many potential influences upon the ultimate expression of an immune response. In this article, Nicky Schweitzer and Roy Anderson investigate the application of mathematics to this highly nonlinear system, and show how it can complement experimentation from both a predictive and interpretative point of view.
Wellcome Research Centre for Parasitic Infections, Department of Biology, Imperial College, London University, UK.
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Schweitzer
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Anderson
D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D016207:Cytokines; D006373:Helminthiasis / Q000276:immunology*; D006790:Host-Parasite Interactions; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000276:immunology; D007108:Immune Tolerance; D008954:Models, Biological; D016176:T-Lymphocyte Subsets / Q000276:immunology; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology
D016207:Cytokines