Adaptation of human rotavirus to cell culture and characterization of the isolated strain.
Human rotavirus strain 649 was isolated from a child with clinical picture of acute intestinal infection in the West European part of the U.S.S.R. This strain was adapted to MA-104 (rhesus monkey kidney) cells. By electrophoresis and haemagglutination it differed from the human rotavirus strain Wa and from the simian strain Sa-11. The productive reproduction of human rotavirus strain 649 may allow its use for the preparation of antigens for diagnostic, immunoprophylaxis, and treatment.
Belorussian Research Institute of Epidemiology and Microbiology, Minsk, U.S.S.R.
V G
VG
Gudkov
P G
PG
Rytik
V V
VV
Shumko
A S
AS
Virinskaya
I V
IV
Nepljuev
J G
JG
Ilkevich
D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology; D000956:Antigens, Viral / Q000276:immunology; D002478:Cells, Cultured; D003429:Cross Reactions; D005243:Feces / Q000382:microbiology; D005759:Gastroenteritis / Q000382:microbiology*; D006801:Humans; D007668:Kidney; D008253:Macaca mulatta; D012401:Rotavirus / Q000145:classification / Q000276:immunology / Q000302:isolation & purification*; D012400:Rotavirus Infections / Q000382:microbiology*; D014776:Virus Cultivation
D000914:Antibodies, Viral; D000956:Antigens, Viral