Detection of p30 antigen in sexual assault case material.
A sandwich enzyme immunoassay for the detection of p30 prostate specific antigen was applied in 52 forensic cases. In each case, immunoassay results were compared with those of the search for spermatozoa and prostatic acid phosphatase analysis. The results indicate that the p30 assay gave no false positive and fewer false negative reactions than the acid phosphatase test. The sensitivities compared to the search for spermatozoa as a reference method were 94.8% for the p30 assay and 84.4% for the acid phosphatase test; the specificities were 95.6% and 90.0% respectively.
Blood Group Laboratory, University of Liège, Belgium.
L
L
Kamenev
M
M
Leclercq
C
C
Francois-Gerard
D000135:Acid Phosphatase / Q000032:analysis; D000951:Antigens, Neoplasm / Q000032:analysis*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007231:Infant, Newborn; D008297:Male; D011237:Predictive Value of Tests; D011467:Prostate / Q000201:enzymology / Q000276:immunology*; D017430:Prostate-Specific Antigen; D011902:Rape / Q000175:diagnosis*; D013094:Spermatozoa
D000951:Antigens, Neoplasm; D000135:Acid Phosphatase; D017430:Prostate-Specific Antigen