Renal masses: characterization with Doppler US.
The vascularity of indeterminate renal masses in 70 patients was investigated prospectively with duplex ultrasound. The peak-systolic Doppler shift frequency obtained from the renal mass was utilized to attempt distinction between benign and malignant lesions. With use of the criterion of a peak-systolic Doppler shift frequency of 2.5 kHz or greater as evidence of neovascularity, 26 of 37 malignant lesions demonstrated tumor signals (70% sensitivity). Thirty-one of 33 benign lesions lacked tumor signals (94% specificity). Both of the false-positive lesions were infections with inflammatory masses, with peak frequencies of 3.0 and 3.7 kHz. Tumor vascularity in most malignant renal mass lesions gives rise to abnormal, high-frequency, Doppler-shifted signals that can aid the differential diagnosis of renal masses.
Kier
R
R
Department of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT 06510.
Taylor
K J
KJ
Feyock
A L
AL
Ramos
I M
IM
D002292:Carcinoma, Renal Cell / Q000098:blood supply / Q000175:diagnosis*; D006801:Humans; D007668:Kidney / Q000098:blood supply / Q000473:pathology*; D007674:Kidney Diseases / Q000175:diagnosis; D007680:Kidney Neoplasms / Q000098:blood supply / Q000175:diagnosis*; D009389:Neovascularization, Pathologic / Q000175:diagnosis; D011446:Prospective Studies; D014465:Ultrasonics; D014463:Ultrasonography