Exanthematic type of pustular psoriasis consisting of two types of pustular lesion.
A 35-year-old female developed generalized pustules within a short period of time. Clinically, two distinct types of pustules were observed, viz. erythematous patches studded with crops of small pustules, and isolated large pustules with a red halo. Histologically, the former were subcorneal spongiform pustules, whereas the latter were unilocular pustules involving the hair follicular infundibulum or a subcorneal unilocular pustule on the palmo-plantar skin. On the basis of the sudden appearance of the pustules without any pre-existing lesions of psoriasis and the histological findings of the spongiform pustules, we made a diagnosis of the exanthematic type of pustular psoriasis. The lesions responded in a dose-dependent fashion to oral cyclosporin.
Department of Dermatology, Tohoku University School of Medicine, Sendai, Japan.
N
N
Matsumura
H
H
Takematsu
S
S
Saijo
K
K
Hashimoto
H
H
Tagami
D000284:Administration, Oral; D000328:Adult; D016572:Cyclosporine / Q000008:administration & dosage; D004305:Dose-Response Relationship, Drug; D005076:Exanthema / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D005533:Foot Dermatoses / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006229:Hand Dermatoses / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D011565:Psoriasis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D012867:Skin / Q000473:pathology*
D016572:Cyclosporine