[Differential diagnosis of necrotizing sarcoid angiitis: necrotizing sarcoid angiitis and collagen disease--a case report].
The chest x-ray showed a bilateral micronodular pattern and hilar lymph nodes. Lung function test revealed a diminished VC, TLC and a reduced compliance and CO diffusion capacity. The histological examination of the lung biopsy showed sarcoid-like necrotising granulomatous formations of the vessel walls and destruction of these. Unusual was the coincidence of a sarcoidal necrotizing angiitis and a connective tissue disease which presented as Raynaud's disease. Antinuclear antibodies and antibodies against SSA-RO and Scleroderma 70 were identified. The histological examination of the skin biopsy showed changes pertaining to scleroderma. In accordance with the definition by Laevitt (4, 5), this disease is a polyarteritis overlap syndrome.
II. Interne Lungenabteilung des Pulmologischen Zentrums der Stadt Wien.
C
C
Armbruster
N
N
Vetter
D000328:Adult; D006801:Humans; D008099:Liver / Q000098:blood supply*; D008168:Lung / Q000098:blood supply*; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000473:pathology; D010488:Polyarteritis Nodosa / Q000473:pathology*; D012507:Sarcoidosis / Q000473:pathology*; D012595:Scleroderma, Systemic / Q000473:pathology*
Zur Differentialdiagnose der nekrotisierenden sarkoidalen Angiitis: Nekrotisierende sarkoidale Angiitis und Kollagenerkrankung--Ein Fallbericht.