Flagellate dermatitis after bleomycin. A histological and immunohistochemical study.
A case of flagellate dermatitis after administration of bleomycin is reported in a patient with Hodgkin's disease. Histopathological and immunohistochemical analysis revealed a drug-induced skin toxic reaction rather than a lymphomatous infiltrate. Pigmentary changes observed after the early erythematous eruption were due to a postinflammatory effect.
Department of Human Pathology, Dermatology Section, University of Pavia, Italy.
L
L
Miori
M
M
Vignini
G
G
Rabbiosi
D000328:Adult; D001761:Bleomycin / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D005260:Female; D006689:Hodgkin Disease / Q000188:drug therapy; D006801:Humans; D007150:Immunohistochemistry; D008214:Lymphocytes / Q000276:immunology / Q000473:pathology; D012867:Skin / Q000276:immunology / Q000473:pathology
D001761:Bleomycin