Genetic systems of red cell blood groups in goats.
Evidence is presented for six genetic systems of goat red cell blood groups. The A system presently consists of one specificity, two alleles, two phenotypes (A1 and no-A1) and appears to be homologous to the A system of sheep. The B system, like its homologue in sheep, is very complex. Fourteen of 21 specificities detected in the present study, i.e. B2, B3, B4, B5, B7, B8, B9, B10, B11, B14, B15, B16, B17 and B20, belong to the B system which involves a large number of phenogroups (31 different B phenogroups identified in 26 sires). Because of their homology with sheep C and R systems, two other genetic systems of goat blood groups are named C and R respectively. Each of the two goat systems is presently a one blood group specificity, two phenotype (C12 and no-C12; R and no-R detectable on the red cells) two allele system. Two specificities, namely E6 and E18, belong to a genetic system called E in which four phenotypes are under the control of two alleles codominant and one recessive at a single locus. The F system involves but a single pair of alleles and two phenotypes (F19 and no-F19). Because of its low frequency in the goats tested, the X13 specificity remains unassigned.
Institut National de la Recherche Agronomique, Centre de Recherches de Jouy-en-Josas, France.
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Nguyen
D000483:Alleles; D000818:Animals; D000918:Antibody Specificity; D001789:Blood Group Antigens / Q000235:genetics*; D000939:Epitopes / Q000235:genetics; D004912:Erythrocytes / Q000378:metabolism*; D005787:Gene Frequency; D008040:Genetic Linkage; D006041:Goats / Q000235:genetics* / Q000276:immunology; D007519:Isoantigens / Q000235:genetics*; D010641:Phenotype; D012689:Sequence Homology, Nucleic Acid
D001789:Blood Group Antigens; D000939:Epitopes; D007519:Isoantigens