Long term use of neuroleptics by schizophrenic patients.
1. Use of antipsychotic medications by schizophrenic patients. 2. Side effects of typical neuroleptics. 3. Dosage strategies for treating schizophrenia. Evidence that high dosage treatment and rapid neuroleptization concepts should be abandoned. 4. Minimal effective dosage in maintenance treatment. Studies attempting to define this regimen. 5. Blood levels of antipsychotics and their clinical relevance. 6. New research strategies, focusing on a) case definition, b) target symptoms, c) clinically stable patients, d) dosage reduction studies.
Dept. of Psychiatry, Faculty of Medicine, University of Calgary, Alberta, Canada.
R
R
Williams
J T
JT
Dalby
J
J
Kennedy
D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006801:Humans; D012559:Schizophrenia / Q000188:drug therapy*
D014150:Antipsychotic Agents