Influence of prior orchiopexy on stage and prognosis of testicular cancer.
Thirty-four cryptorchid testis cancer cases were studied, of whom 9 patients had prior orchiopexy at the time of cancer diagnosis. Disease stage in this group was: stage I = 4, stage II = 1 and stages III and IV = 4 cases. Seventy-eight percent of these cases (n = 7) had non-seminomas; 4 of these patients died. In the uncorrected cryptorchidism group (n = 25), disease stage was: stage I = 12, stage II = 9 and stages III and IV = 4 cases. Of these cases, 64% (n = 16) had seminomas and 6 patients died. Orchiopexy marginally reduced the symptomatic interval for subsequent cancer and probably decreased the risk of seminoma development. Orchiopexy did not lead to a more favourable disease presentation or prognosis because of the adverse bias of advanced-stage non-seminomas in this group.
Jones
B J
BJ
Irish Testicular Tumour Registry, Dublin, Ireland.
Thornhill
J A
JA
O'Donnell
B
B
Kelly
D G
DG
Walsh
A
A
Fennelly
J J
JJ
Fitzpatrick
J M
JM
D000328:Adult; D002648:Child; D003456:Cryptorchidism / Q000601:surgery*; D004407:Dysgerminoma / Q000453:epidemiology* / Q000473:pathology; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D009373:Neoplasms, Germ Cell and Embryonal / Q000453:epidemiology* / Q000473:pathology; D011379:Prognosis; D012307:Risk Factors; D013736:Testicular Neoplasms / Q000453:epidemiology* / Q000473:pathology; D013737:Testis / Q000473:pathology