Insulin stimulatory action on amino acid uptake in bovine adrenal cortex or glomerulosa zone.
1. Insulin stimulated the [1-14C] methylaminoisobutyric acid and [1-14C] aminoisobutyric acid uptake in the bovine adrenal cortex or in the glomerulosa zone through the A system. 2. Verapamil nullified the insulin stimulatory action indicating that this hormonal action is probably related to the voltage-dependent Ca2+ channels.
Centro de Endocrinologia Experimental, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
M G
MG
Fauth
K P
KP
Barreto
G F
GF
Wassermann
D000302:Adrenal Cortex / Q000187:drug effects* / Q000378:metabolism; D000596:Amino Acids / Q000378:metabolism*; D000621:Aminoisobutyric Acids / Q000378:metabolism; D000818:Animals; D001693:Biological Transport, Active / Q000187:drug effects; D002417:Cattle; D066298:In Vitro Techniques; D007328:Insulin / Q000494:pharmacology*; D014700:Verapamil / Q000494:pharmacology; D015384:Zona Glomerulosa / Q000187:drug effects / Q000378:metabolism
D000596:Amino Acids; D000621:Aminoisobutyric Acids; D007328:Insulin; C017911:2-(methylamino)isobutyric acid; D014700:Verapamil