A comparative study of oral glucose tolerance tests in Nigerian women on three types of steroidal contraceptives.
Oral glucose tolerance tests (OGTT) were performed on 146 Nigerian women volunteers using one of three types of steroidal contraceptives: high-dose combined pills; low-dose combined pills and injectable progesterone. Twenty-six appropriately matched nonusers served as controls. The OGTT curves were analysed using the H-index (HI). Women on injectable progesterone and high-dose combined pills, respectively, had significantly higher (P less than 0.05) mean HI than the controls. The low-dose combined pills had the least effect on carbohydrate metabolism.
Department of Chemical Pathology, Faculty of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria.
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Oyelola
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Olusi
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Ayangade
D000328:Adult; D000704:Analysis of Variance; D001786:Blood Glucose / Q000032:analysis; D050260:Carbohydrate Metabolism; D003271:Contraceptive Agents, Female / Q000008:administration & dosage / Q000494:pharmacology*; D003277:Contraceptives, Oral, Combined / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D007273:Injections, Intramuscular; D009549:Nigeria; D011374:Progesterone / Q000008:administration & dosage / Q000494:pharmacology*
D001786:Blood Glucose; D003271:Contraceptive Agents, Female; D003277:Contraceptives, Oral, Combined; D011374:Progesterone