Selective sigma ligands block stimulant effects of cocaine.
Drug Development Group, NIDA Addiction Research Center, Baltimore, Maryland 21224.
M
M
Menkel
P
P
Terry
M
M
Pontecorvo
J L
JL
Katz
J M
JM
Witkin
D000818:Animals; D014151:Anti-Anxiety Agents / Q000494:pharmacology; D014150:Antipsychotic Agents / Q000494:pharmacology; D000697:Central Nervous System Stimulants / Q000037:antagonists & inhibitors*; D003042:Cocaine / Q000037:antagonists & inhibitors*; D004305:Dose-Response Relationship, Drug; D008024:Ligands; D008297:Male; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D009292:Narcotic Antagonists; D011957:Receptors, Opioid / Q000187:drug effects*; D017480:Receptors, sigma; D013268:Stimulation, Chemical
D014151:Anti-Anxiety Agents; D014150:Antipsychotic Agents; D000697:Central Nervous System Stimulants; D008024:Ligands; D009292:Narcotic Antagonists; D011957:Receptors, Opioid; D017480:Receptors, sigma; D003042:Cocaine