[Clinical research on the tolerance for and the interferon-inducing activity of amiksin].
Tolerance and interferon-inducing activity of amixine, an interferon inducer, was studied by the double-blind method clinically in healthy volunteers given tableted amixine orally in doses of 0.125-0.25 g by different schedules. According to clinical laboratory examinations and studies of indirect parameters of labor capacity amixine was found to be tolerable for man. The amount of interferon in the blood serum depended on the schedule of administration of the inducer, the optimal being 1-2 amixine tablets at least 2 days apart.
N P
NP
Chizhov
T T
TT
Smol'skaia
P I
PI
Baĭchenko
R I
RI
Luk'ianova
V M
VM
Teslenko
G P
GP
Bavra
I A
IA
Romanchenko
E B
EB
Shatalov
F I
FI
Ershov
E B
EB
Tazulakhova
D000293:Adolescent; D000328:Adult; D004311:Double-Blind Method; D004361:Drug Tolerance; D006801:Humans; D007369:Interferon Inducers / Q000627:therapeutic use*; D007372:Interferons / Q000097:blood; D008297:Male; D010919:Placebos; D011581:Psychological Tests / Q000379:methods; D011603:Psychophysiology; D013607:Tablets; D013994:Tilorone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D013997:Time Factors
D007369:Interferon Inducers; D010919:Placebos; D013607:Tablets; D007372:Interferons; D013994:Tilorone
Klinicheskie issledovaniia perenosimosti i interferonindutsiruiushcheĭ aktivnosti amiksina.