Detection of tumor antigens with monoclonal antibodies: immunopathology and immunodiagnosis.
The immunocytochemical demonstration, using monoclonal antibodies, of diverse cellular constituents has improved our understanding of many aspects of oncology. This review will focus on this approach to facilitate the detection of human tumors, improve their histological classification and provide functional parameters with potential aetiological, prognostic and/or therapeutic value.
Neville
A M
AM
Ludwig Institute for Cancer Research, London, UK.
D000911:Antibodies, Monoclonal / Q000276:immunology*; D000912:Antibodies, Neoplasm / Q000276:immunology*; D000951:Antigens, Neoplasm / Q000032:analysis*; D006801:Humans; D007159:Immunologic Tests; D015994:Incidence; D016023:Integrins / Q000276:immunology; D009362:Neoplasm Metastasis; D009363:Neoplasm Proteins / Q000276:immunology; D009369:Neoplasms / Q000175:diagnosis* / Q000276:immunology; D011518:Proto-Oncogene Proteins / Q000032:analysis / Q000276:immunology; D018719:Erb-b2 Receptor Tyrosine Kinases
D000911:Antibodies, Monoclonal; D000912:Antibodies, Neoplasm; D000951:Antigens, Neoplasm; D016023:Integrins; D009363:Neoplasm Proteins; D011518:Proto-Oncogene Proteins; D018719:Erb-b2 Receptor Tyrosine Kinases