[Increased expression of proliferation keratins K 6 and K 16 in unaffected skin in exacerbated psoriasis].
The in vivo expression of the proliferation keratins K 6 and K 16 is characteristic for hyperproliferative diseases and positive in psoriatic lesions. Our study was performed in order to investigate the in vitro expression of proliferation keratins and to settle the question whether they are also inducible in organ cultures of uninvolved psoriatic skin, possibly differing from normal skin.
Universitäts-Hautklinik Köln.
A
A
Wevers
H G
HG
Arnold
B
B
Bonnekoh
H J
HJ
Schulze
G
G
Mahrle
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D002455:Cell Division / Q000502:physiology*; D005260:Female; D006801:Humans; D007633:Keratins / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D010455:Peptides / Q000032:analysis*; D011565:Psoriasis / Q000473:pathology*; D012867:Skin / Q000473:pathology*
D010455:Peptides; D007633:Keratins
Vermehrte Expression der Proliferationskeratine K 6 und K 16 in der unbefallenen Haut bei exazerbierter Psoriasis.