[A therapeutic concept for the treatment of inoperable esophageal carcinoma].
From 1/87 to 12/88, 20 patients with anatomically or functionally inoperable carcinomas of the esophagus (cT1-3/N0-2/M0-1) were treated by endoluminal Ir-192 HDR brachytherapy (1-3 sessions, each 5-7 Gy) and percutaneous irradiation (50-70 Gy/2 Gy). In 10 cases a bouginage or combined dilatation and retrograde Nd-Yag-laser debulking was done before irradiation. The response of the treatment was documented by endoscopy (degree of stenoses) and symptoms (dysphagia score according to De Meester). In 95% of all cases the degree of stenoses was diminished and an improvement of dysphagia was found in 100%. The mean duration of oral uptake of properly chewed food could be prolonged to 308 days.
Universitätsklinik für Radiologie, Abteilung für Thorax- und Hyperbare Chirurgie, Graz.
B
B
Pakisch
P
P
Kohek
G
G
Stücklschweiger
F G
FG
Smolle-Jüttner
E
E
Poier
A
A
Fall
H
H
Leitner
G
G
Friehs
A
A
Hackl
D001918:Brachytherapy / Q000379:methods; D002277:Carcinoma / Q000150:complications / Q000532:radiotherapy*; D003131:Combined Modality Therapy / Q000379:methods; D004106:Dilatation; D004938:Esophageal Neoplasms / Q000150:complications / Q000532:radiotherapy*; D004940:Esophageal Stenosis / Q000209:etiology / Q000628:therapy; D004947:Esophagus / Q000528:radiation effects / Q000601:surgery; D006801:Humans; D007496:Iridium Radioisotopes / Q000627:therapeutic use; D053685:Laser Therapy; D010166:Palliative Care / Q000379:methods; D010315:Particle Accelerators; D011879:Radiotherapy Dosage; D012074:Remission Induction
D007496:Iridium Radioisotopes
Ein Therapiekonzept zur Behandlung inoperabler Osophaguskarzinome.