title: Hyaluronic acid deposition in cardiac myxomas: localization using a hyaluronate-specific binding protein.
abstract: Myxomas are the most common primary tumors of the heart. These lesions contain a gelatinous, ground-substancelike material which has been described as glycosaminoglycan in nature. Using a newly developed, cartilage-derived hyaluronic acid-binding protein and a modification of the avidin-biotin immunostaining procedure, we demonstrate that hyaluronic acid is contained in the jellylike material of cardiac myxomas.
authors.affiliation: Department of Pathology, University of California, San Francisco 94143.
authors.forename: B N
authors.initials: BN
authors.lastname: Hendin
authors.forename: M T
authors.initials: MT
authors.lastname: Longaker
authors.forename: W E
authors.initials: WE
authors.lastname: Finkbeiner
authors.forename: L J
authors.initials: LJ
authors.lastname: Roberts
authors.forename: R
authors.initials: R
authors.lastname: Stern
mesh_terms: D000328:Adult; D002352:Carrier Proteins; D005260:Female; D006338:Heart Neoplasms / Q000737:chemistry* / Q000473:pathology; D006801:Humans; D018960:Hyaluronan Receptors; D006820:Hyaluronic Acid / Q000032:analysis*; D008875:Middle Aged; D009206:Myocardium / Q000737:chemistry / Q000473:pathology; D009232:Myxoma / Q000737:chemistry* / Q000473:pathology; D013194:Staining and Labeling
chemical_list: D002352:Carrier Proteins; D018960:Hyaluronan Receptors; D006820:Hyaluronic Acid