[Histogenesis of pleomorphic adenomas of the salivary glands].
Histogenesis of pleomorphic adenomas was investigated by histological and electron microscopical methods. Histochemically alkaline phosphatase activity was revealed in transformed cells. Positive immunohistochemical reaction was shown in cells of pleomorphic adenomas with polyclonal antibodies against the smooth muscle myosin, human carbonic anhydrase III and monoclonal antibodies to cytokeratins N8, N17, N18, vimentin (clone NT-30) and to membrane epithelial antigen. It is concluded that these tumours are of the epithelial nature.
SHamsutdinov
N Sh
NSh
D008949:Adenoma, Pleomorphic / Q000737:chemistry / Q000473:pathology*; D000469:Alkaline Phosphatase / Q000032:analysis; D000951:Antigens, Neoplasm / Q000032:analysis; D004848:Epithelium / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D007124:Immunoenzyme Techniques; D007633:Keratins / Q000032:analysis; D012468:Salivary Gland Neoplasms / Q000737:chemistry / Q000473:pathology*; D014746:Vimentin / Q000032:analysis
D000951:Antigens, Neoplasm; D014746:Vimentin; D007633:Keratins; D000469:Alkaline Phosphatase
Gistogenez pleomorfnykh adenom sliunnykh zhelez.