[Evaluation of sensitivity and specificity of various staining methods for the detection of myocardial fibrosis].
Fifty bioptic endomyocardial samples from 15 patients with idiopathic dilatative cardiomyopathy have been stained with PicroSirius, Masson-Goldner, Van Gieson Verhoeff, AFOG. The extension of stained areas has been evaluated by morphometry using a videoscan. As control sections samples have been taken from lower third of the right ventricle at autopsies of healthy subjects dying in road accidents. Morphometric analysis of subendocardial interstitial and perivascular fibrosis has been performed. For the authors the most useful stain in the evidentiation of fibrosis was PicroSirius both in the bioptic samples and the autoptic ones.
Colecchia
M
M
Servizio di anatomia patologica, Ospedale Maggiore di Lodi.
Leopardi
O
O
D000293:Adolescent; D000328:Adult; D004719:Endomyocardial Fibrosis / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D013194:Staining and Labeling / Q000379:methods*
Valutazione della sensibilità e della specificità di metodiche di colorazione per la evidenziazione della fibrosi miocardica.