[Use of a microtest plate method in pregnancy thrombocyte serology].
In search of a time saving concept for verifying a neonatal allo-immune thrombocytopenia (NATP) we tested the suitability of a solid phase platelet assay for antibodies (ab) which might induce NATP. Compared to PSIFT the test is equally appropriate for the detection of platelet specific and HLA ab. Using maternal, paternal, P1A1 neg. and random platelets the test gives quick answers to: a) is one dealing with a NATP? b) is anti-P1A1 involved?
Sehrbundt
M
M
Institut für Transfusionsmedizin, Universität zu Köln.
Timoteo
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R
Krüger
J
J
D016824:Antigens, Human Platelet; D001792:Blood Platelets / Q000276:immunology*; D003601:Cytotoxicity Tests, Immunologic; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007231:Infant, Newborn; D039661:Integrin beta3; D007518:Isoantibodies / Q000032:analysis*; D007519:Isoantigens / Q000276:immunology*; D011247:Pregnancy; D013921:Thrombocytopenia / Q000097:blood / Q000175:diagnosis*
D016824:Antigens, Human Platelet; C061248:ITGB3 protein, human; D039661:Integrin beta3; D007518:Isoantibodies; D007519:Isoantigens
Einsatz einer Mikrotest-Platten-Methode in der Schwangeren-Thrombozytenserologie.