[Effect of non-steroidal anti-inflammatory agents on interferon induction].
Nonsteroid antiinflammatory agents (NAIA) such as antipyrine, butadion, acetylsalicylic acid, sodium salicylate, stampyrine and 4-iodantipyrine are not interferonogenic. Still, they stimulated interferonogenic action of poly(G).poly(C) in studies on animals. Relation between the interferon-stimulating action of the NAIA and their effect on activity of prostaglandin and the influence on the immune system was suggested.
Evstropov
A N
AN
Gritsenko
L N
LN
Khudonogova
Z P
ZP
Iavorovskaia
V E
VE
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000494:pharmacology*; D004357:Drug Synergism; D007274:Injections, Intraperitoneal; D007369:Interferon Inducers; D007372:Interferons / Q000096:biosynthesis* / Q000097:blood; D051379:Mice; D011066:Poly C / Q000008:administration & dosage / Q000494:pharmacology*; D011068:Poly G / Q000008:administration & dosage / Q000494:pharmacology*; D013268:Stimulation, Chemical; D013997:Time Factors
D000894:Anti-Inflammatory Agents, Non-Steroidal; D007369:Interferon Inducers; D011068:Poly G; D011066:Poly C; D007372:Interferons
Vliianie nesteroidnykh protivovospalitel'nykh sredstv na induktsiiu interferona.