A related epitope is consistently present on glycoprotein C of herpes simplex virus type 1 and 2.
A monoclonal antibody (VE8) directed to glycoprotein C of herpes simplex virus type 1 (HSV-1) cross-reacted with all HSV type 2 (HSV-2) strains tested. Positive reaction was also observed with all investigated HSV-1 strains, indicating that the related epitope is consistently present in HSV-1 and HSV-2.
Eis-Hübinger
A M
AM
Institute of Medical Microbiology and Immunology of the University, Bonn, F.R.G.
Kleim
J P
JP
Mohr
K
K
Schneweis
K E
KE
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D003429:Cross Reactions; D000939:Epitopes / Q000032:analysis*; D015151:Immunoblotting; D051379:Mice; D008807:Mice, Inbred BALB C; D018139:Simplexvirus / Q000276:immunology*; D014759:Viral Envelope Proteins / Q000276:immunology*
D000911:Antibodies, Monoclonal; D000939:Epitopes; D014759:Viral Envelope Proteins; C048232:glycoprotein C, herpes simplex virus type 2; C038535:glycoprotein gC, herpes simplex virus type 1