title: [Bilateral interpleural analgesia in a patient with multiple myeloma].
abstract: The case of one patient with multiple myeloma and thoracic pain during myeloptysis is described. Bilateral interpleural analgesia was accomplished with 10 ml of 0.375% bupivacaine with adrenaline (5 micrograms/ml) in both hemithorax and bilateral infusion at a rate of 3 ml/h started immediately and maintained during 24 hours. Analgesia was then obtained by means of a bolus pattern 10 ml/6 h until myeloptysis finished. Analgesic effectiveness was evaluated through visual analogue scale (VAS). Plasmatic levels of bupivacaine were found below toxic levels; maximum concentration was (1.12 microgram/ml) at the steady state (5 x t 1/2). Difficulty in treatment of pain and utility of interpleural analgesia is suggested.
authors.affiliation: Servicio de Anestesiología, Reanimación y Terapéutica del Dolor, Hospital Germans Trias i Pujol, Badalona, Barcelona.
authors.forename: A
authors.initials: A
authors.lastname: Montes
authors.forename: J L
authors.initials: JL
authors.lastname: Aguilar
mesh_terms: D000368:Aged; D000698:Analgesia / Q000379:methods*; D001859:Bone Neoplasms / Q000150:complications*; D002045:Bupivacaine / Q000008:administration & dosage* / Q000097:blood; D002637:Chest Pain / Q000188:drug therapy* / Q000209:etiology; D004837:Epinephrine / Q000008:administration & dosage; D006801:Humans; D008297:Male; D009101:Multiple Myeloma / Q000150:complications*; D010014:Osteolysis / Q000150:complications; D010166:Palliative Care; D010994:Pleura
chemical_list: D002045:Bupivacaine; D004837:Epinephrine
vernacular_title: Analgesia interpleural bilateral en un paciente afectado de mieloma múltiple.