title: Primary hepatic carcinoid tumor. An electron microscopic and immunohistochemical study.
abstract: A case of primary carcinoid tumor of the liver with striking morphologic and electron microscopic features is reported. Conventional histologic examination showed a prominent paranuclear clear zone in numerous tumor cells. By electron microscopic examination, this clear zone corresponded to a paranuclear mass of intermediate filaments admixed with neurosecretory granules and other cytoplasmic organelles.
authors.affiliation: Department of Pathology, Memorial Hospital of Rhode Island, Pawtucket 02860.
authors.forename: N
authors.initials: N
authors.lastname: Sioutos
authors.forename: S
authors.initials: S
authors.lastname: Virta
authors.forename: N
authors.initials: N
authors.lastname: Kessimian
mesh_terms: D000368:Aged; D000951:Antigens, Neoplasm / Q000032:analysis; D002272:Carcinoembryonic Antigen / Q000032:analysis; D002276:Carcinoid Tumor / Q000737:chemistry / Q000276:immunology / Q000473:pathology*; D002864:Chromogranins / Q000032:analysis; D003594:Cytoplasmic Granules / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D008113:Liver Neoplasms / Q000737:chemistry / Q000276:immunology / Q000473:pathology*; D008297:Male; D008562:Membrane Glycoproteins / Q000032:analysis; D008854:Microscopy, Electron; D018396:Mucin-1; D015388:Organelles / Q000473:pathology; D010751:Phosphopyruvate Hydratase / Q000032:analysis
chemical_list: D000951:Antigens, Neoplasm; D002272:Carcinoembryonic Antigen; D002864:Chromogranins; D008562:Membrane Glycoproteins; D018396:Mucin-1; D007633:Keratins; D010751:Phosphopyruvate Hydratase