title: Near-triploid myeloblastic transformation of chronic myeloid leukemia with bizarre blast morphology.
abstract: We describe a case of chronic myeloid leukemia (CML) in myeloblastic transformation in which near-triploidy with complex karyotypic abnormalities occurred together with unusual blast morphology. A review of the literature shows that near-triploidy is extremely unusual in blastic transformation (BT) of CML.
authors.affiliation: University Department of Pathology, Queen Mary Hospital, Pokfulam, Hong Kong.
authors.forename: Y L
authors.initials: YL
authors.lastname: Kwong
authors.forename: A Y
authors.initials: AY
authors.lastname: Chan
authors.forename: L C
authors.initials: LC
authors.lastname: Chan
authors.forename: K F
authors.initials: KF
authors.lastname: Wong
authors.forename: Y C
authors.initials: YC
authors.lastname: Chu
mesh_terms: D001752:Blast Crisis; D001853:Bone Marrow / Q000473:pathology; D002869:Chromosome Aberrations; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000235:genetics* / Q000473:pathology; D007962:Leukocytes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D014314:Trisomy