title: [Centroblast morphology: a morphometric evaluation by means of computer-aided image analysis].
abstract: In cytologic preparations, cell images from 30 cases of high grade malignant Non-Hodgkin's lymphoma (NHL) and 10 cases of tonsillitis have been analysed using a colour TV microscope system, high resolution scanning and image processing. Multivariate analysis of 30 cell features allowed satisfying recognition and discrimination of centrocytes, centrocyte-like centroblasts, ordinary centroblasts and multilobated centroblasts. In addition, according to their image analytical data, the ordinary centroblasts from NHL formed 5, and those from tonsillitis 4 well defined, homogeneous clusters. Even at simultaneous analysis, there was an essential overlap only between centroblast subtype 3 from NHL and subtype 9 from tonsillitis, but reliable discrimination of all the rest.
authors.affiliation: Pathologisches Institut, Universität Würzburg.
authors.forename: M
authors.initials: M
authors.lastname: Bergmann
authors.forename: H
authors.initials: H
authors.lastname: Harms
authors.forename: R
authors.initials: R
authors.lastname: Albert
authors.forename: M
authors.initials: M
authors.lastname: Droese
authors.forename: H K
authors.initials: HK
authors.lastname: Müller-Hermelink
mesh_terms: D003201:Computers; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology / Q000648:ultrastructure; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology* / Q000648:ultrastructure; D015999:Multivariate Analysis; D013690:Television; D014069:Tonsillitis / Q000473:pathology*
vernacular_title: Uber die Morphologie der Zentroblasten: Eine morphometrische Untersuchung mit Hilfe der Bildanalyse.