title: Vitamin and mineral status in physically active men: effects of a high-potency supplement.
abstract: Changes in nutritional status during supplementation with a high-potency multivitamin-mineral supplement were examined in 22 physically active men randomly assigned to take a supplement (n = 11) or placebo (n = 11) for approximately 12 wk. Four-day dietary intakes, blood concentrations, and urinary excretions of selected vitamins and minerals were measured before, during (approximately 6 and 12 wk), and after supplementation. No changes were observed in blood concentrations of vitamins A and C and measures of zinc, magnesium, and calcium status; the supplement provided less than 300% of the recommended dietary allowance (RDA) of these nutrients. In contrast, blood concentrations of thiamin, riboflavin, vitamins B-6 and B-12, pantothenate, and biotin increased significantly (P less than 0.05) by 6 wk to values that were maintained until the end of the supplementation. These vitamins were provided in amounts that ranged from 396% (biotin) to 6250% (vitamin B-6) of the RDA. Urinary excretions of these vitamins also increased during supplementation and both blood and urine values returned to presupplementation concentrations at approximately 13.5 wk postsupplementation.
authors.affiliation: Department of Military Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814-4799.
authors.forename: A
authors.initials: A
authors.lastname: Singh
authors.forename: F M
authors.initials: FM
authors.lastname: Moses
authors.forename: P A
authors.initials: PA
authors.lastname: Deuster
mesh_terms: D000328:Adult; D015930:Diet Records; D004435:Eating; D015444:Exercise / Q000502:physiology*; D006801:Humans; D008297:Male; D008903:Minerals / Q000008:administration & dosage* / Q000097:blood / Q000652:urine; D009752:Nutritional Status; D011897:Random Allocation; D014803:Vitamin B Complex / Q000008:administration & dosage / Q000097:blood / Q000652:urine; D014815:Vitamins / Q000008:administration & dosage* / Q000097:blood / Q000652:urine
chemical_list: D008903:Minerals; D014815:Vitamins; D014803:Vitamin B Complex