title: Stress increases the secretory product of rat nasal mucosa goblet cells.
abstract: The effect of stress on the secretory activity of rat nasal mucosa goblet cells was examined by quantitative histochemistry. Mucosa was prepared from the nasal septum of male rats with or without electric shock applied to the tail. Mucosa was fixed with formaldehyde and stained with alcian blue. The epithelial layer was further dissected, and examined microscopically. The percentage of stained area was estimated with the aid of a microscope connected to a computerized video system. The stained area, which corresponded to the secretory granules of mucosal goblet cells, was greater in the electrically shocked group than the control group. This result raises the possibility that stress enhances the secretory activity of goblet cells in nasal mucosa.
authors.affiliation: Department of Otolaryngology, Meiji College of Oriental Medicine, Kyoto, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Tachibana
authors.forename: H
authors.initials: H
authors.lastname: Senuma
authors.forename: T
authors.initials: T
authors.lastname: Ebara
authors.forename: K
authors.initials: K
authors.lastname: Kumamoto
mesh_terms: D000423:Alcian Blue; D000818:Animals; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D004558:Electric Stimulation; D004848:Epithelium / Q000648:ultrastructure; D007091:Image Processing, Computer-Assisted; D008297:Male; D009297:Nasal Mucosa / Q000378:metabolism* / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains; D013194:Staining and Labeling; D013312:Stress, Physiological / Q000378:metabolism* / Q000473:pathology
chemical_list: D000423:Alcian Blue