Meningiomas differentiating to arachnoid trabecular cells: a proposal for histological subtype "arachnoid trabecular cell meningioma".
Three cases of meningiomas which had abundant small vacuoles in the tumor tissue are reported. By electron microscopy, the tumor cells exhibited long and thin processes, the tips of which were united by desmosomes. The tumor tissue was revealed to have wide extracellular spaces which corresponded to the vacuoles observed by light microscopy. In previous literature, various terms have been used when referring to this meningioma, such as microcystic meningioma or vacuolated meningioma. Since the ultrastructure of the tumor showed similarity to that of normal arachnoid trabecular cells, we propose to call the tumor "arachnoid trabecular cell meningioma" denoting its morphological nature clearly.
Ito
H
H
Department of Neurosurgery, Kitasato University School of Medicine, Kanagawa, Japan.
Kawano
N
N
Yada
K
K
Kameya
T
T
D002454:Cell Differentiation; D003593:Cytoplasm / Q000648:ultrastructure; D006801:Humans; D008577:Meningeal Neoplasms / Q000378:metabolism / Q000473:pathology*; D008579:Meningioma / Q000378:metabolism / Q000473:pathology*; D008854:Microscopy, Electron; D013194:Staining and Labeling; D014617:Vacuoles / Q000648:ultrastructure