Effect of immunosuppressive drugs on cytokine gene transcription studied by message amplification phenotyping (MAPPing) polymerase chain reaction.
Nelson
P A
PA
Department of Immunology, Vertex Pharmaceuticals Inc., Cambridge, Massachusetts.
Kawamura
A
A
Akselband
Y
Y
Peattie
D A
DA
Aldape
R A
RA
Harding
M W
MW
D002478:Cells, Cultured; D016572:Cyclosporine / Q000494:pharmacology; D016207:Cytokines / Q000235:genetics*; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007376:Interleukin-2 / Q000235:genetics; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology / Q000502:physiology*; D011090:Polyenes / Q000494:pharmacology; D016133:Polymerase Chain Reaction / Q000379:methods; D011401:Promoter Regions, Genetic / Q000187:drug effects*; D012333:RNA, Messenger / Q000187:drug effects / Q000235:genetics; D020123:Sirolimus; D016559:Tacrolimus / Q000494:pharmacology; D014158:Transcription, Genetic / Q000187:drug effects*; D001613:beta 2-Microglobulin / Q000235:genetics
D016207:Cytokines; D007166:Immunosuppressive Agents; D007376:Interleukin-2; D011090:Polyenes; D012333:RNA, Messenger; D001613:beta 2-Microglobulin; D016572:Cyclosporine; D020123:Sirolimus; D016559:Tacrolimus