Decreased responsiveness of platelets to a stable prostacyclin analogue in patients with Crohn's disease. Reversal by n-3 polyunsaturated fatty acids.
Jaschonek
K
K
Medizinische Klinik und Poliklinik, Universität Tübingen, Germany.
Clemens
M R
MR
Scheurlen
M
M
D001792:Blood Platelets / Q000187:drug effects*; D003424:Crohn Disease / Q000097:blood* / Q000178:diet therapy; D004042:Dietary Fats, Unsaturated / Q000494:pharmacology*; D004355:Drug Stability; D005231:Fatty Acids, Unsaturated / Q000494:pharmacology*; D005395:Fish Oils / Q000627:therapeutic use*; D006801:Humans; D016285:Iloprost / Q000378:metabolism*; D044006:Receptors, Epoprostenol; D011982:Receptors, Prostaglandin / Q000187:drug effects*
D004042:Dietary Fats, Unsaturated; D005231:Fatty Acids, Unsaturated; D005395:Fish Oils; D044006:Receptors, Epoprostenol; D011982:Receptors, Prostaglandin; D016285:Iloprost