Growing human B lymphocytes in the CD40 system.
One approach to generating human monoclonal antibodies relies on the development of culture techniques allowing the long-term growth of most B lymphocytes, a property of the CD40 system.
Banchereau
J
J
Schering-Plough Corporation, Laboratory for Immunological Research, Dardilly, France.
Rousset
F
F
D000911:Antibodies, Monoclonal; D015703:Antigens, CD / Q000276:immunology*; D000944:Antigens, Differentiation, B-Lymphocyte / Q000276:immunology*; D001402:B-Lymphocytes / Q000166:cytology* / Q000276:immunology; D019013:CD40 Antigens; D002455:Cell Division; D002461:Cell Line, Transformed; D004854:Herpesvirus 4, Human; D006801:Humans
D000911:Antibodies, Monoclonal; D015703:Antigens, CD; D000944:Antigens, Differentiation, B-Lymphocyte; D019013:CD40 Antigens