title: A statistical method for the comparison of a discrete diagnostic test with several continuous diagnostic tests.
abstract: In this paper we study a statistic that is suitable for comparing a discrete diagnostic marker to one or more continuous diagnostic markers. Test procedures and confidence intervals are based on asymptotic normality. The statistic is applicable for correlated data in which all the markers are obtained for each subject. The statistic was studied for use in comparing two markers for rectal bleeding. Examples for this application and two more general applications are presented.
authors.affiliation: Department of Radiology, Duke University Medical Center, Durham, North Carolina 27710.
authors.forename: C A
authors.initials: CA
authors.lastname: Beam
authors.forename: H S
authors.initials: HS
authors.lastname: Wieand
mesh_terms: D000704:Analysis of Variance; D001699:Biometry; D002272:Carcinoembryonic Antigen / Q000032:analysis; D003110:Colonic Neoplasms / Q000473:pathology; D003933:Diagnosis; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis / Q000517:prevention & control; D006400:Hematocrit; D006801:Humans; D007415:Intestinal Obstruction / Q000601:surgery; D008403:Mass Screening / Q000379:methods; D008433:Mathematics; D009010:Monte Carlo Method; D009780:Occult Blood; D010051:Ovarian Neoplasms / Q000150:complications; D010166:Palliative Care; D011379:Prognosis; D012004:Rectal Neoplasms / Q000473:pathology*
chemical_list: D002272:Carcinoembryonic Antigen