title: Diversion colitis in children with severe gastrointestinal motility disorders.
abstract: We found colitis in 11 of 14 children, 4 months to 7 yr after surgical diversion of the colon for chronic intestinal pseudo-obstruction. Colonoscopic examination was incidental during placement of a catheter for colon manometry and transit studies. All 14 children had complained of diffuse, poorly localized abdominal pain, but only three had a history of bloody stools. Diversion colitis had not previously been suspected in six of eight affected children without hematochezia. Biopsies showed a nonspecific acute and chronic inflammation and/or nodular lymphoid hyperplasia. There was no correlation between the duration of the colonic diversion and the severity of the colitis. Diversion colitis may be an indolent inflammatory nidus and a potential cause for repeated bacteremia, abdominal pain, and bleeding.
authors.affiliation: Department of Pediatrics, Harbor/UCLA Medical Center, Torrance.
authors.forename: J J
authors.initials: JJ
authors.lastname: Ordein
authors.forename: C
authors.initials: C
authors.lastname: Di Lorenzo
authors.forename: A
authors.initials: A
authors.lastname: Flores
authors.forename: P E
authors.initials: PE
authors.lastname: Hyman
mesh_terms: D002648:Child; D002675:Child, Preschool; D003092:Colitis / Q000473:pathology*; D003112:Colonic Pseudo-Obstruction / Q000601:surgery*; D003113:Colonoscopy; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011183:Postoperative Complications / Q000473:pathology*