Successful treatment of acute postoperative pulmonary hypertension with nifedipine.
We report the successful use of nifedipine in the treatment of acute pulmonary hypertension in an infant after a cardiac operation. This patient had undergone total surgical correction of his truncus arteriosus malformation. He had signs of severe pulmonary artery hypertension unresponsive to hyperventilation, oxygenation, sedation, and a myriad of vasodilators. Nifedipine, 0.2 mg/kg every 4 hours, effectively treated his pulmonary artery hypertension and allowed for a smooth postoperative course and positive outcome.
Davis
D A
DA
Pediatric Heart Institute, Temple University School of Medicine, Philadelphia, Pennsylvania.
Russo
P
P
D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy*; D007223:Infant; D008297:Male; D009543:Nifedipine / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000188:drug therapy*; D014339:Truncus Arteriosus, Persistent / Q000601:surgery*
D009543:Nifedipine