Limb body-wall complex in association with sirenomelia sequence.
Limb body-wall complex and sirenomelia sequence are uncommon birth defects and their association is extremely rare. Their overlapping manifestations and their concurrence in our patient suggest that they share a common cause and belong to a group of pathologically closely related conditions. Embryonic vascular disruption may be a common pathogenesis in both anomalies.
Tang
T T
TT
Department of Pathology, Medical College of Wisconsin, Milwaukee.
Oechler
H W
HW
Hinke
D H
DH
Segura
A D
AD
Franciosi
R A
RA
D000015:Abnormalities, Multiple / Q000473:pathology; D000652:Amniotic Band Syndrome / Q000473:pathology; D004480:Ectromelia / Q000473:pathology; D005260:Female; D005322:Premature Rupture of Fetal Membranes; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D000509:alpha-Fetoproteins / Q000032:analysis
D000509:alpha-Fetoproteins