[Pericardial C-reactive protein. A marker of agonal cardiac disease ?].
We studied the influence of the agonal period on the concentrations of acute phase proteins in biological fluids obtained from 26 autopsy cases. We found significant differences for C-reactive protein concentrations in serum and in pericardial fluid, between short and long agonies. The other acute phase proteins studied (alpha-1 antitrypsin, alpha-2 macroglobulin, haptoglobin) failed to show any significant difference in serum and pericardial fluid levels between the two types of agony. The increase in C-reactive protein level in the pericardial fluid is attributed to an "agonal pericarditis" which may result from an agonal myocardial necrosis. Our results could be of interest in forensic medicine.
Laurier
E
E
Institut de Médecine Légale de médecine Sociale, Université du Droit et de la Santé, Lille.
Gosset
D
D
Hennache
B
B
Nuttens
M C
MC
Debuire
B
B
Lenoir
L
L
Muller
P H
PH
D000328:Adult; D000368:Aged; D002097:C-Reactive Protein / Q000032:analysis / Q000378:metabolism*; D005260:Female; D005554:Forensic Medicine; D006242:Haptoglobins / Q000032:analysis / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D010496:Pericardium / Q000378:metabolism*; D000515:alpha 1-Antitrypsin / Q000032:analysis / Q000378:metabolism; D000511:alpha-Macroglobulins / Q000032:analysis / Q000378:metabolism
D006242:Haptoglobins; D000515:alpha 1-Antitrypsin; D000511:alpha-Macroglobulins; D002097:C-Reactive Protein
La protéine C-réactive péricardique. Un marqueur de la souffrance cardiaque agonique?