title: Burkitt's lymphoma presenting with blindness: a case report.
abstract: A 10-year-old schoolboy was referred to the Ophthalmic Unit of Ahmadu Bello University Teaching Hospital because of sudden loss of sight following 5 days of severe frontal headache. The child had bilateral ptosis with internal and external ophthalmoplegia and fixed and dilated pupils. There was no papilloedema. Eight days later, a jaw tumour and a rapidly enlarging abdominal tumour appeared. A fine needle aspiration biopsy of the jaw tumour confirmed Burkitt's lymphoma. Combination chemotherapy with cyclophosphamide, vincristine and methotrexate (COM) led to a rapid resolution of the jaw and abdominal tumour but the child never regained his sight. Cerebrospinal fluid examination was not helpful in reaching a diagnosis.
authors.affiliation: Department of Paediatrics, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.
authors.forename: M
authors.initials: M
authors.lastname: Ibrahim
authors.forename: W N
authors.initials: WN
authors.lastname: Ogala
authors.forename: F A
authors.initials: FA
authors.lastname: Babaoye
authors.forename: O O
authors.initials: OO
authors.lastname: Onabolu
authors.forename: E A
authors.initials: EA
authors.lastname: Afolayan
mesh_terms: D000008:Abdominal Neoplasms / Q000556:secondary*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D001766:Blindness / Q000209:etiology*; D001932:Brain Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D002051:Burkitt Lymphoma / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D002648:Child; D003520:Cyclophosphamide / Q000008:administration & dosage; D003937:Diagnosis, Differential; D006801:Humans; D007573:Jaw Neoplasms / Q000556:secondary*; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D003520:Cyclophosphamide; D008727:Methotrexate