[The direct stimulating action of thyroliberin on the biosynthesis of total protein in cultured liver cells of rat fetuses].
In experiments using fetal rat liver cultured cells TRH was shown to stimulate total protein synthesis but not RNA synthesis during long incubation. Somatostatin affected neither protein synthesis nor RNA synthesis in cultured liver cells. Possible physiological role of peripheral TRH during perinatal period in the rat is discussed.
Fedotov
V P
VP
Gudoshnikov
V I
VI
Baranova
I N
IN
D000818:Animals; D002478:Cells, Cultured / Q000187:drug effects / Q000378:metabolism; D005333:Fetus; D007328:Insulin / Q000494:pharmacology; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D014176:Protein Biosynthesis; D011506:Proteins / Q000187:drug effects*; D012313:RNA / Q000096:biosynthesis / Q000187:drug effects; D051381:Rats; D013004:Somatostatin / Q000494:pharmacology; D013268:Stimulation, Chemical; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology*; D013997:Time Factors
D007328:Insulin; D011506:Proteins; D013004:Somatostatin; D013973:Thyrotropin-Releasing Hormone; D012313:RNA
Priamoe stimuliruiushchee vliianie tiroliberina na biosintez summarnogo belka v kul'tiviruemykh kletkakh pecheni plodov krys.