title: Monoclonal antibodies to the components of the high-molecular-mass aminoacyl-tRNA synthetase complex.
abstract: Six monoclonal antibodies to the components of the rabbit multienzyme aminoacyl-tRNA synthetase complex were generated and characterised. Two, F7 and F31 were directed against arginyl-tRNA synthetase, two, F8 and F25 against glutamyl-tRNA synthetase, and two, F6 and F12 recognised 38 and 43 kDa polypeptides, respectively. All antibodies were species-specific and failed to affect the activity of the respective enzymes.
authors.affiliation: Institute of Molecular Biology, Academy of Sciences of the USSR, Moscow.
authors.forename: V V
authors.initials: VV
authors.lastname: Filonenko
authors.forename: A D
authors.initials: AD
authors.lastname: Wolfson
authors.forename: O A
authors.initials: OA
authors.lastname: Wartanyan
authors.forename: S F
authors.initials: SF
authors.lastname: Beresten
mesh_terms: D000604:Amino Acyl-tRNA Synthetases / Q000737:chemistry / Q000276:immunology*; D000818:Animals; D000911:Antibodies, Monoclonal / Q000737:chemistry*; D000918:Antibody Specificity; D000939:Epitopes / Q000276:immunology; D005975:Glutamate-tRNA Ligase / Q000737:chemistry / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D008970:Molecular Weight; D009097:Multienzyme Complexes / Q000737:chemistry / Q000276:immunology*; D010449:Peptide Mapping; D011817:Rabbits
chemical_list: D000911:Antibodies, Monoclonal; D000939:Epitopes; D009097:Multienzyme Complexes; D000604:Amino Acyl-tRNA Synthetases; D005975:Glutamate-tRNA Ligase