title: [Basic factors in the stability of RNA-duplexes. The contribution of dehydration].
abstract: The enthalpy effect of hydrate envelope deformation was first taken into consideration for estimating the influence of aqueous medium on the stability of RNA duplexes. In addition two rarely used parameters (macroscopic value of dielectric water permeability and entropy effect of dehydration) were employed. According to the energy model described the contribution of the free energy of dehydration to the RNA duplexes stability is significant even in comparison with that of the interstrand stacking.
authors.forename: V S
authors.initials: VS
authors.lastname: Shvarts
authors.forename: A V
authors.initials: AV
authors.lastname: Kant
authors.forename: N M
authors.initials: NM
authors.lastname: Frolova
mesh_terms: D004553:Electric Conductivity; D009692:Nucleic Acid Heteroduplexes; D012313:RNA / Q000737:chemistry*; D013816:Thermodynamics; D014867:Water / Q000737:chemistry*
chemical_list: D009692:Nucleic Acid Heteroduplexes; D014867:Water; D012313:RNA
vernacular_title: Osnovnye faktory stabil'nosti RNK-dupleksov. Vklad degidratsii.