title: [Activity of human natural killer cells against target cells possessing different sensitivity to interferon].
abstract: The cytotoxic activity of peripheral blood natural killers (NK) against target cells (TC) J-96 and L-929 with high sensitivity to interferon (IFN) action, J-41 and MCB resistant to IFN action and line K-562 labelled by H3-uridine was studied in 14 hrs cytotoxic test. It has been shown that human TC J-96 didn't differ from the J-41 in their sensitivity to NK cytotoxicity and they are strongly resistant to NK than TC K-562. The murine TC L-929 as the human TC didn't differ from the MCB in their sensitivity to NK lysis and had also the same sensitivity to NK as the K-562 cells.
authors.forename: S B
authors.initials: SB
authors.lastname: Cheknev
authors.forename: A N
authors.initials: AN
authors.lastname: Narovlianskiĭ
authors.forename: A M
authors.initials: AM
authors.lastname: Amchenkova
authors.forename: A M
authors.initials: AM
authors.lastname: Sorokin
authors.forename: Ia E
authors.initials: IaE
authors.lastname: Khesin
authors.forename: F I
authors.initials: FI
authors.lastname: Ershov
mesh_terms: D000818:Animals; D002460:Cell Line; D003601:Cytotoxicity Tests, Immunologic; D003602:Cytotoxicity, Immunologic; D006801:Humans; D007372:Interferons / Q000494:pharmacology*; D007694:Killer Cells, Natural / Q000276:immunology*; D051379:Mice; D008810:Mice, Inbred C57BL; D014407:Tumor Cells, Cultured / Q000276:immunology
chemical_list: D007372:Interferons
vernacular_title: Aktivnost' estestvennykh killerov cheloveka protiv kletok-misheneĭ, obladaiushchikh razlichnoĭ chuvstvitel'nost'iu k interferonu.