title: [Results of experimental radiobiological studies made within the 10-kilometer zone of the Chernobyl AES accident].
abstract: A study was made of the effect of high radioactive contamination on the animal organism (C57BL/6 mice) and HeLa cell culture within the ten-kilometer zone of the Chernobyl A.P.S. accident. The total radiation dose, as calculated by a gamma-component, was 0.09 to 2 Gy. A long-term exposure of mice within the zone (cumulative dose of 1.8 to 2 Gy) caused a significant decrease in bone marrow stem potencies and changes in the brain vascular system; subsequent acute exposure of animals increased interferon titres in the serum to a much greater extent than a single acute exposure did. As to HeLa cells, irradiation there of with doses of 0.09 to 0.4 Gy during 15-20 postirradiation generations caused a decrease in the proliferative activity, an emergence of cells with micronuclei and of giant cells, and remote cell death.
authors.forename: I I
authors.initials: II
authors.lastname: Pelevina
authors.forename: I N
authors.initials: IN
authors.lastname: Riabov
authors.forename: I A
authors.initials: IA
authors.lastname: Riabtsev
authors.forename: B F
authors.initials: BF
authors.lastname: Gulev
authors.forename: V Ia
authors.initials: VIa
authors.lastname: Gotlib
authors.forename: G G
authors.initials: GG
authors.lastname: Afanas'ev
authors.forename: S N
authors.initials: SN
authors.lastname: Vasilenko
authors.forename: M L
authors.initials: ML
authors.lastname: Gumeniuk
authors.forename: L E
authors.initials: LE
authors.lastname: Kozlova
authors.forename: A A
authors.initials: AA
authors.lastname: Kondarov
mesh_terms: D000059:Accidents; D000818:Animals; D001853:Bone Marrow / Q000528:radiation effects; D001921:Brain / Q000528:radiation effects; D006367:HeLa Cells / Q000528:radiation effects; D006801:Humans; D007372:Interferons / Q000097:blood; D051379:Mice; D009688:Nuclear Reactors; D011829:Radiation Dosage; D011848:Radioactive Pollutants / Q000633:toxicity*; D014455:Ukraine
chemical_list: D011848:Radioactive Pollutants; D007372:Interferons
vernacular_title: Itogi éksperimental'nykh radiobiologicheskikh issledovaniĭ v 10-kilometrovoĭ zone avarii na ChAES.