[The value of parameters of iron metabolism in the differential diagnosis of anemias].
As a result of investigations into the diagnostic validity of selected haematologic-morphological and clinical-chemical test factors of iron metabolism in the diagnosis of hypochromic anaemia, the examined test faktora are differently evaluated as individual parameters and in their combination. 1. Haematocrit (PCV) is equal to the determination of haemoglobin concentration as a search parameter. 2. The number of reticulocytes, copper and zinc as well as caeruloplasmin have a separating effect as individual parameters on the examined classes of iron deficiency and tumour and infect anaemia. 3. Iron has no value as a individual parameter. It is only in combination with TEBK and the haematologic test factors that is has a diagnostic value. 4. In contrast, ferritin as an individual parameter is of primary importance and should be used extensively in the laboratory diagnosis of hypochromic anaemia. 5. TEBK and transferrin may be supposed to be equal in their diagnostic value. 6. When used in combination, haemoglobin, MCV, TEBK, Transferrin, and ferritin have effective separating function. They permit hypochromic anaemia to be widely assigned to one or another kind of the examined classes.
Baudach
A
A
Institut für Laboratoriumsdiagnostik, Klinikums Berlin-Buch.
Tille
D
D
Schleusner
A
A
Müller
K
K
Gerisch
A
A
Lobers
W
W
D000740:Anemia / Q000097:blood / Q000175:diagnosis*; D000747:Anemia, Hypochromic / Q000097:blood / Q000175:diagnosis*; D002570:Ceruloplasmin / Q000032:analysis; D003937:Diagnosis, Differential; D004906:Erythrocyte Count; D005293:Ferritins / Q000097:blood; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007501:Iron / Q000378:metabolism*; D012156:Reticulocytes / Q000473:pathology; D014168:Transferrin / Q000032:analysis
D006454:Hemoglobins; D014168:Transferrin; D005293:Ferritins; D007501:Iron; D002570:Ceruloplasmin
Die Wertigkeit von Parametern des Eisenstoffwechsels in der Differentialdiagnose von Anämien.