title: PIXE determination of essential trace elements in some traditional Chinese medicines.
abstract: The essential trace elements in 30 traditional Chinese medicines, (24 tonics and 6 nontonics) were determined by proton-induced X-ray emission. The authors' previous suggestion that traditional Chinese medicines may be classified by the order of magnitude of their essential trace elements, thus indicating their pharmacological effects, is not justified. The pharmacological effect of a trace element or its essentiality may be dependent on some ligand that can be chelated with it. A nonlinear mapping algorithm, however, shows that the 30 traditional Chinese medicines are nearly separated into two groups, indicating their tonic or nontonic pharmacological effects.
authors.affiliation: Institute of Atomic Energy, Beijing, People's Republic of China.
authors.forename: L
authors.initials: L
authors.lastname: Xiao
authors.forename: J F
authors.initials: JF
authors.lastname: Qin
mesh_terms: D004365:Drugs, Chinese Herbal / Q000032:analysis* / Q000145:classification; D007501:Iron / Q000032:analysis; D008345:Manganese / Q000032:analysis; D013052:Spectrometry, X-Ray Emission; D014131:Trace Elements / Q000032:analysis*
chemical_list: D004365:Drugs, Chinese Herbal; D014131:Trace Elements; D008345:Manganese; D007501:Iron