[Quinidine-induced thrombocytopenia].
We present the case of drug-dependent thrombocytopenic purpura due to the treatment with quinidine. IgG quinidine-dependent antibodies in patient serum were detected in the platelet immunofluorescence test. They were bound to GP Ib on platelet membrane.
Maślanka
K
K
Zakład Serologii Instytutu Hematologii, Warszawa.
Majcher
A
A
Bykowska
K
K
D001323:Autoantibodies / Q000032:analysis / Q000276:immunology; D001792:Blood Platelets / Q000187:drug effects* / Q000276:immunology; D005117:Cardiac Complexes, Premature / Q000188:drug therapy*; D004342:Drug Hypersensitivity / Q000097:blood / Q000150:complications* / Q000276:immunology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D008875:Middle Aged; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood / Q000139:chemically induced* / Q000276:immunology; D011802:Quinidine / Q000009:adverse effects*
D001323:Autoantibodies; D007074:Immunoglobulin G; D011802:Quinidine
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