title: [Relapsing polychondritis in a patient with myelodysplastic syndrome].
abstract: Relapsing polychondritis is a rare disorder of uncertain origin characterized by recurrent inflammation of cartilage. A case of myelodysplastic syndrome (MDS) associated with relapsing polychondritis is reported. A 60-year-old man who had been diagnosed as MDS was admitted because of pain and swelling in the bilateral preauricular regions and cheek. A diagnosis of relapsing polychondritis was made by coexistence of auricular chondritis, arthropathy, ocular inflammation and audio-vestibular disturbance. He also developed ocular palsies and optic neuritis. He was treated with prednisolone, azathioprine, dapsone, and then with steroid pulse therapy. Moreover, plasmapheresis and high dose gamma-globulin therapy were undertaken. However, all these treatments were unsuccessful and he died of respiratory failure.
authors.affiliation: First Department of Internal Medicine, Kurume University School of Medicine.
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: E
authors.initials: E
authors.lastname: Nakamura
authors.forename: K
authors.initials: K
authors.lastname: Naitoh
authors.forename: I
authors.initials: I
authors.lastname: Utsunomiya
authors.forename: K
authors.initials: K
authors.lastname: Matsuo
authors.forename: S
authors.initials: S
authors.lastname: Osabe
authors.forename: J
authors.initials: J
authors.lastname: Honda
authors.forename: K
authors.initials: K
authors.lastname: Yoshida
authors.forename: K
authors.initials: K
authors.lastname: Egami
authors.forename: H
authors.initials: H
authors.lastname: Natori
mesh_terms: D001379:Azathioprine / Q000008:administration & dosage; D003622:Dapsone / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000150:complications* / Q000628:therapy; D009902:Optic Neuritis / Q000209:etiology; D010956:Plasmapheresis; D011081:Polychondritis, Relapsing / Q000209:etiology* / Q000628:therapy; D011239:Prednisolone / Q000008:administration & dosage; D005719:gamma-Globulins / Q000008:administration & dosage
chemical_list: D005719:gamma-Globulins; D003622:Dapsone; D011239:Prednisolone; D001379:Azathioprine