Changes in the testicular acid and alkaline phosphatase activities at different durations following prostatectomy: a correlative study with spermatogenesis.
The purpose of this investigation was to make a correlative study between spermatogenesis and testicular acid and alkaline phosphatase activities in mature prostatectomized animals at different post-operative periods. The results demonstrate that there was a significant augmentation in the activity of testicular acid and alkaline phosphatases subsequent to 14 and 21 days of prostatectomy. A parallel quantitative study of spermatogenesis at stage VII of the seminiferous cycle, namely, type A spermatogonia (ASg), preleptotene spermatocytes (pLSc), mid-pachytene spermatocytes (mPSc) and step 7 spermatids (7sd), revealed that there was a significant reduction in the number of step 7 spermatids after 14 and 21 days. No change was observed in the above testicular enzymes and spermatogenesis after 7 days of prostatectomy. Therefore, it is concluded that prostatectomy can alter the above testicular enzyme activities and spermatogenesis in chronic prostatectomized state.
Chaudhuri
A
A
Reproductive Physiology Unit, Department of Physiology, Calcutta, India.
Biswas
N M
NM
Ghosh
D
D
Ghosh
P K
PK
D000135:Acid Phosphatase / Q000378:metabolism*; D000469:Alkaline Phosphatase / Q000378:metabolism*; D000818:Animals; D005854:Germ Cells / Q000502:physiology; D008297:Male; D011468:Prostatectomy; D051381:Rats; D011919:Rats, Inbred Strains; D013076:Sperm Count; D013087:Spermatids / Q000502:physiology; D013091:Spermatogenesis / Q000502:physiology*; D013194:Staining and Labeling; D013737:Testis / Q000201:enzymology*; D013997:Time Factors
D000469:Alkaline Phosphatase; D000135:Acid Phosphatase