[Results of treatment of paralytic ileus caused by diffuse intra-abdominal metastasis with motilin. A pilot study of 25 patients].
In a pilot-study 25 patients presenting with a paralytic ileus due to diffuse intraabdominal metastases were treated with motilin. There were 16 male (64%) and nine female (36%) patients. Gastric cancer was the most frequent cause (40%), followed by pancreatic (36%), and colorectal (20%) cancer. 36% had received a postoperative chemotherapy before commencing the motilin-scheme. In 92% motilin therapy was started within 48 hours after the diagnosis of paralytic ileus. There were no serious side-effects of motilin therapy. In approximately 80% the pretherapeutic state was improved. Thus, it seems worthwhile to investigate the influence of motilin on paralytic ileus in incurable cancer patients in a prospective controlled trial.
Meyer
J
J
Klinik und Poliklinik für Allgemeine Chirurgie, Westfälische Wilhelms-Universität, Münster.
Sulkowski
U
U
Preusser
P
P
D003131:Combined Modality Therapy; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000601:surgery*; D006801:Humans; D007262:Infusions, Intravenous; D007418:Intestinal Pseudo-Obstruction / Q000188:drug therapy*; D008297:Male; D009037:Motilin / Q000627:therapeutic use*; D010166:Palliative Care; D010534:Peritoneal Neoplasms / Q000556:secondary* / Q000601:surgery; D011183:Postoperative Complications / Q000188:drug therapy*
D009037:Motilin
Ergebnisse der Behandlung des paralytischen Ileus wegen diffuser intraabdomineller Metastasierung mit Motilin. Eine Pilotstudie an 25 Patienten.