An immunohistochemically distinct population of cat ciliary ganglion cells.
In the cat ciliary ganglion, 16% and 23% respectively of the neurons are surrounded by nerve fibers immunoreactive to calcitonin gene-related peptide (CGRP) and somatostatin (SOM). One-third of the ganglion cell perikarya are immunoreactive to neuropeptide Y (NPY). Analysis of the coincidence of immunoreactivities shows a striking correlation. Practically all of the ganglion cells surrounded by CGRP-like immunoreactive (LI) nerve fibers also are surrounded by SOM-LI nerve processes and demonstrate NPY-LI perikarya. These observations define a subset of NPY-LI ciliary ganglion cells with a particular peptidergic input and perhaps a specific physiologic function.
Grimes
P A
PA
Department of Ophthalmology, University of Pennsylvania School of Medicine, Philadelphia 19104.
McGlinn
A M
AM
Stone
R A
RA
D000818:Animals; D002924:Ciliary Body / Q000166:cytology* / Q000648:ultrastructure; D005455:Fluorescent Antibody Technique; D005724:Ganglia / Q000166:cytology* / Q000648:ultrastructure; D007150:Immunohistochemistry; D009479:Neuropeptides / Q000276:immunology / Q000494:pharmacology; D011817:Rabbits; D013194:Staining and Labeling
D009479:Neuropeptides