Low dose epirubicin for hypercalcemia associated with renal pelvis carcinoma.
We present a case of hypercalcemia associated with a renal pelvis squamous neoplasm. Severe hyperleukocytosis was also present, resembling a leukaemoid reaction. After failure of standard therapy, we performed a trial of low dose epirubicin in this patient, obtaining a short-term clinical remission. Although a palliative non-toxic effect seems to be achievable with this approach, further studies are needed to ascertain the role of chemotherapy in the long-term control of this condition.
Castillo
J M
JM
Department of Urology, Hospital Virgen del Camino, Pamplona, Spain.
Illarramendi
J J
JJ
Santiago
A
A
Sebastián
J L
JL
D000368:Aged; D002116:Calcitonin / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000150:complications*; D002295:Carcinoma, Transitional Cell / Q000150:complications*; D015251:Epirubicin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000188:drug therapy* / Q000209:etiology; D007680:Kidney Neoplasms / Q000150:complications*; D007955:Leukemoid Reaction / Q000209:etiology; D009378:Neoplasms, Multiple Primary / Q000150:complications*; D010166:Palliative Care
D015251:Epirubicin; D002116:Calcitonin