Fibrous papule of the nose with granular cells: two cases.
Two cases of fibrous papule of the nose (FPN) with granular cell features are presented and discussed. Both lesions have classic architectural features of FPN; however, the main stromal cells show large cytoplasmic granules of the type seen in granular cells. We are uncertain of the significance of these findings. Our hypotheses include a perifollicular granular cell reaction and a granular degenerative change of local dermal dendrocytes.
Guitart
J
J
Department of Pathology, Cleveland Clinic Foundation, Ohio 44195.
Bergfeld
W F
WF
Tuthill
R J
RJ
D016586:Granular Cell Tumor / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009669:Nose Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D013194:Staining and Labeling