title: Purification of an Arg-Gly-Asp selective matrix receptor from brain synaptic plasma membranes.
abstract: Brain synaptic plasma membranes specifically associated with matrix protein monolayers containing the Arg-Gly-Asp sequence recognized by integrin-type adhesion receptors. Experiments using fibronectin affinity chromatography to identify the synaptosomal receptors responsible for this interaction led to the purification of a 55 kDa Arg-Gly-Asp recognition protein that is labelled by antibodies against the alpha 5 beta 1 integrin.
authors.affiliation: Center for the Neurobiology of Learning and Memory, University of California, Irvine 92717-3800.
authors.forename: B A
authors.initials: BA
authors.lastname: Bahr
authors.forename: G
authors.initials: G
authors.lastname: Lynch
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001921:Brain / Q000378:metabolism*; D002448:Cell Adhesion; D016326:Extracellular Matrix Proteins / Q000378:metabolism*; D006624:Hippocampus / Q000378:metabolism; D016023:Integrins / Q000302:isolation & purification / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D008969:Molecular Sequence Data; D051381:Rats; D011919:Rats, Inbred Strains; D013570:Synaptic Membranes / Q000378:metabolism*
chemical_list: D016326:Extracellular Matrix Proteins; D016023:Integrins