title: Microbial pathogenesis and tyrosine dephosphorylation: surprising 'bedfellows'.
abstract: The importance of parasite-directed phosphatases in such diseases as smallpox and the bubonic plague emphasizes the need to understand the molecular events associated with the normal function of protein tyrosine phosphatase in eukaryotic cells.
authors.affiliation: Department of Biochemistry, Purdue University, West Lafayette, Indiana 47907.
authors.forename: J C
authors.initials: JC
authors.lastname: Clemens
authors.forename: K
authors.initials: K
authors.lastname: Guan
authors.forename: J B
authors.initials: JB
authors.lastname: Bliska
authors.forename: S
authors.initials: S
authors.lastname: Falkow
authors.forename: J E
authors.initials: JE
authors.lastname: Dixon
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D008969:Molecular Sequence Data; D010766:Phosphorylation; D019000:Phosphotyrosine; D011499:Protein Processing, Post-Translational; D017027:Protein Tyrosine Phosphatases / Q000502:physiology*; D011505:Protein-Tyrosine Kinases / Q000502:physiology; D011994:Recombinant Proteins / Q000378:metabolism; D012689:Sequence Homology, Nucleic Acid; D014443:Tyrosine / Q000031:analogs & derivatives / Q000378:metabolism*; D014616:Vaccinia virus / Q000201:enzymology* / Q000235:genetics / Q000472:pathogenicity; D014764:Viral Proteins / Q000235:genetics / Q000378:metabolism*; D015007:Yersinia / Q000201:enzymology* / Q000235:genetics / Q000472:pathogenicity
chemical_list: D001426:Bacterial Proteins; D011994:Recombinant Proteins; D014764:Viral Proteins; D019000:Phosphotyrosine; D014443:Tyrosine; D011505:Protein-Tyrosine Kinases; D017027:Protein Tyrosine Phosphatases