title: Comparison between two versus three patches single pulse shock defibrillation in pigs.
abstract: The aim of the study was to test the hypothesis that defibrillation with a single pulse shock can be obtained at lower energy using three epicardial patches configuration (one cathode and two anodes) instead of the conventional two patches. The total surface area of the two- and three-patches configuration was the same (10 cm2 vs 9.9 cm2). Epicardial spatial configuration was planned by using a computerized heart model. In ten anesthetized open-chest pigs, ventricular fibrillation was induced by using AC current through the mesh plaque epicardial custom-designed electrodes, and the minimum energy requirement for defibrillation was determined 15 seconds after the onset of stable ventricular fibrillation. Results were as follows (mean +/- standard deviation): Defibrillation Threshold 16 +/- 9 J 9 +/- 5 J P less than 0.01 CONCLUSIONS: three epicardial patches configuration significantly reduces energy requirements for defibrillation compared with two patches when single pulse shock is used.
authors.affiliation: Istituto di Cardiologia e Cardiochirurgia, Università Cattolica del S. Cuore, Rome, Italy.
authors.forename: A S
authors.initials: AS
authors.lastname: Montenero
authors.forename: G
authors.initials: G
authors.lastname: Bombardieri
authors.forename: C
authors.initials: C
authors.lastname: Barilaro
authors.forename: P
authors.initials: P
authors.lastname: Di Francesco
authors.forename: S
authors.initials: S
authors.lastname: Bertazzoni
authors.forename: P
authors.initials: P
authors.lastname: Santarelli
authors.forename: E
authors.initials: E
authors.lastname: Pisanó
authors.forename: F
authors.initials: F
authors.lastname: Alessandrini
authors.forename: G
authors.initials: G
authors.lastname: Possati
mesh_terms: D000818:Animals; D004554:Electric Countershock / Q000295:instrumentation* / Q000379:methods; D004567:Electrodes, Implanted; D019736:Prostheses and Implants; D013552:Swine; D014693:Ventricular Fibrillation / Q000628:therapy*