[The effect of hyperbaric oxygenation on glycosylated proteins in diabetes mellitus].
Hyperbaric oxygenation (HBO) effects on the levels of circulating glycosylated proteins with various life spans in the blood stream (glycosylated hemoglobin (GH) and serum glycosylated fructose amine (SF) were studied in diabetes mellitus patients not suffering from vascular complications but developing various microangiopathies. Measurements of blood glycosylated proteins and mean daily glycemia carried out over the course of HBO treatment in the diabetics without microangiopathies evidenced an essential reduction of blood GH, SF, and glucose, reaching, in some cases, the normal values. Patients with vascular involvement (lower limb angiopathy, nephropathy, retinopathy) exposed to HBO developed but a trend to reduction of blood levels of glycosylated proteins and glucose. These results indicate a positive therapeutic effect of HBO courses on the status of diabetics with slightly manifest microvascular involvement. In cases with grave vascular involvement exposure to HBO appears inefficient.
Viktorova
L N
LN
Ananchenko
V G
VG
Gorodetskiĭ
V K
VK
Vasilenko
V V
VV
Navodnyĭ
O A
OA
D000293:Adolescent; D000328:Adult; D001798:Blood Proteins / Q000032:analysis*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000628:therapy; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000628:therapy; D005260:Female; D006023:Glycoproteins; D006801:Humans; D006931:Hyperbaric Oxygenation; D008297:Male; D008875:Middle Aged; D000093422:Glycated Serum Proteins
D001798:Blood Proteins; D006023:Glycoproteins; D000093422:Glycated Serum Proteins
Vliianie giperbaricheskoĭ oksigenatsii na glikirovannye belki pri sakharnom diabete.