[Immunohistochemical demonstration of neurohormonal polypeptides in primary carcinoid tumor of testis].
A primary carcinoid tumor of testis was studied. The tumor cells showed a strong positive reaction to argyrophil or argentaffin stainings, and neuroendocrine granules were identified by electron microscopy. Immunohistochemically, tumor cells expressed various markers such as those for NSE, synaptophysin, CG, Leu-7, 5-HT, HCG, cytokeratin, EMA, CEA and PACP, which indicated the special multiple directions of differentiation of cells possessing neuroendocrinal, epithelial or carcinoembryonic behavior.
Zhang
H M
HM
Department of Pathology, Norman Bethune Medical University.
D014408:Biomarkers, Tumor / Q000032:analysis*; D002276:Carcinoid Tumor / Q000378:metabolism* / Q000648:ultrastructure; D006063:Chorionic Gonadotropin / Q000032:analysis; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000032:analysis; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009418:S100 Proteins / Q000032:analysis; D013736:Testicular Neoplasms / Q000378:metabolism* / Q000648:ultrastructure; D013737:Testis / Q000648:ultrastructure
D014408:Biomarkers, Tumor; D006063:Chorionic Gonadotropin; D009418:S100 Proteins; D006897:Hydroxyindoleacetic Acid