[Clinical evaluation of hypopharyngeal cancer].
Clinical results of cases of hypopharyngeal carcinoma treated from 1966 to 1990 at Kyushu University Hospital were investigated. In 1966-1972, all cases were treated with only radical operation. We used FAR therapy since 1972, and preoperative chemotherapy (CDDP and Peplomycin) in addition to FAR therapy since 1984. The crude five-year survival rate of the operative therapy-group (25 cases in 1966-1972) was 24%, and that of the FAR therapy-group with or without operation (47 cases in 1972-1980) was 38%. Although it was cumulative survival rate by Kaplan-Meier's method, the five-year survival rate of the group (16 cases in 1984-1990) treated with a combination of FAR therapy, preoperative-chemotherapy, and operation was 76%. The improvement in the survival rate and the role of preoperative treatment (FAR therapy and chemotherapy) are discussed.
Komiyama
S
S
Dept. of Otorhinolaryngology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Masuda
A
A
Tomita
K
K
Kuratomi
Y
Y
Zingu
K
K
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D007013:Hypopharynx / Q000601:surgery; D008197:Lymph Node Excision; D017663:Peplomycin; D011879:Radiotherapy Dosage; D015996:Survival Rate; D014801:Vitamin A / Q000008:administration & dosage
D001761:Bleomycin; D014801:Vitamin A; D017663:Peplomycin; D002945:Cisplatin; D005472:Fluorouracil