C4: Rodgers and Chido typing.
Rodgers (Rg) and Chido (Ch)-typing, by means of haemagglutination inhibition, has been performed on 136 plasma/serum samples selected by or submitted to the 1989 Workshop. All were tested for two Rg and six Ch antigenic determinants and a proportion were also tested for WH. The established interrelationships for the antigenic determinants have been fully supported and previously reported associations with C4 allotypes have been maintained. A second example of the Ch phenotype Ch:-1, 2,-3,4,5-6 was detected in an Italian family with the B3 allotype.
Giles
C M
CM
Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK.
D000595:Amino Acid Sequence; D003181:Complement C4 / Q000235:genetics* / Q000276:immunology; D000939:Epitopes / Q000032:analysis*; D005838:Genotype; D006385:Hemagglutination Inhibition Tests; D006720:Homozygote; D006801:Humans; D010641:Phenotype; D011110:Polymorphism, Genetic; D011487:Protein Conformation
D003181:Complement C4; D000939:Epitopes