title: Postangioplasty restenosis rate between segments of the major coronary arteries.
abstract: Conflicting data have been published regarding the rate of postangioplasty restenosis observed in diverse segments of the coronary tree. However, these studies may be criticized for their biased selection of patients, methods of analysis, and definitions of restenosis. In the present study, 1,353 patients underwent a successful coronary dilatation of greater than or equal to 1 site. In all, 1,234 patients (91%) had a follow-up angiogram after 6 months, or earlier when indicated by symptoms. All films were processed and analyzed at the thoraxcenter core laboratory with the coronary angiography analysis system (automated contour detection). Restenosis was considered present if the diameter stenosis at follow-up was greater than 50%. No differences in restenosis rates were observed between coronary segments using this categorical definition. A continuous approach was also used; absolute changes in minimal luminal diameter adjusted for vessel size were used in order to allow comparison between vessels of different sizes (relative loss). No significant differences were observed between the coronary segments with this continuous approach. These results suggest that restenosis is a ubiquitous phenomenon without any predilection for a particular site in the coronary tree.
authors.affiliation: Catheterization Laboratory, Erasmus University, Rotterdam, The Netherlands.
authors.forename: W R
authors.initials: WR
authors.lastname: Hermans
authors.forename: B J
authors.initials: BJ
authors.lastname: Rensing
authors.forename: J C
authors.initials: JC
authors.lastname: Kelder
authors.forename: P J
authors.initials: PJ
authors.lastname: de Feyter
authors.forename: P W
authors.initials: PW
authors.lastname: Serruys
mesh_terms: D000704:Analysis of Variance; D015906:Angioplasty, Balloon, Coronary; D016009:Chi-Square Distribution; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000473:pathology / Q000628:therapy; D006801:Humans; D011859:Radiography; D012008:Recurrence