Scarless fetal healing. Therapeutic implications.
The purpose of this report is to call attention to the fetal wound healing process as a blueprint for ideal tissue repair. Wound healing in the fetus is fundamentally different from healing in the adult. Fetal tissue repair occurs rapidly and in the absence of scar formation. Because scarring and fibrosis dominate some diseases in every area of medicine, an understanding of fetal wound healing should help develop therapeutic strategies to avert the devastating consequences of excessive scar formation.
Adzick
N S
NS
Fetal Treatment Program, University of California, San Francisco 94143-0570.
Longaker
M T
MT
D000328:Adult; D002921:Cicatrix / Q000503:physiopathology / Q000517:prevention & control; D002971:Cleft Lip / Q000601:surgery; D005109:Extracellular Matrix / Q000737:chemistry; D005333:Fetus / Q000502:physiology* / Q000601:surgery; D006801:Humans; D006820:Hyaluronic Acid / Q000032:analysis / Q000502:physiology / Q000627:therapeutic use*; D014945:Wound Healing / Q000187:drug effects / Q000502:physiology*
D006820:Hyaluronic Acid