[Hematopoietic growth factors].
In the paper the role of interleukin-3, granulocyte-macrophage colony stimulating factor (GM-CSF), granulocyte-colony stimulating factor (G-CSF) and macrophage colony stimulating factor (M-CSF), in the proliferation and differentiation of haemopoietic cells and pathogenesis of leukaemia are reviewed. Role of erythropoietin, thrombopoietin and other thrombopoiesis-stimulating factors in the development of hematopoietic is presented. Potential applications of recombinant haemopoietic growth factors in the treatment of myelodysplastic syndromes. AIDS and other haematologic, infections and neoplastic disorders are also discussed.
Robak
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Pracownia Farmakologii Klinicznej Akademii Medycznej, Lodzi.
D000163:Acquired Immunodeficiency Syndrome / Q000097:blood / Q000628:therapy; D004921:Erythropoietin / Q000502:physiology* / Q000627:therapeutic use; D058851:GPI-Linked Proteins; D016179:Granulocyte Colony-Stimulating Factor / Q000502:physiology / Q000627:therapeutic use; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000502:physiology / Q000627:therapeutic use; D006402:Hematologic Diseases / Q000097:blood / Q000628:therapy; D006410:Hematopoiesis / Q000187:drug effects / Q000502:physiology*; D016298:Hematopoietic Cell Growth Factors / Q000502:physiology* / Q000627:therapeutic use; D006412:Hematopoietic Stem Cells / Q000166:cytology* / Q000187:drug effects / Q000473:pathology; D006801:Humans; D066298:In Vitro Techniques; D007377:Interleukin-3 / Q000502:physiology / Q000627:therapeutic use; D008562:Membrane Glycoproteins; D000090204:Mesothelin; D011506:Proteins / Q000502:physiology / Q000627:therapeutic use
D058851:GPI-Linked Proteins; D016298:Hematopoietic Cell Growth Factors; D007377:Interleukin-3; D008562:Membrane Glycoproteins; D011506:Proteins; D004921:Erythropoietin; D016179:Granulocyte Colony-Stimulating Factor; D016178:Granulocyte-Macrophage Colony-Stimulating Factor; D000090204:Mesothelin
Krwiotwórcze czynniki wzrostowe.