title: Comparison of plateletpheresis with two different cell separators using 100 identical donors.
abstract: Plateletpheresis with the cell separator COBE Spectra and Fenwal CS 3000 was compared in 100 identical donors. The Spectra was significantly superior with regard to collection efficiency (53% vs. 42%, p less than .001) and leukocyte contamination of the platelet products (.1 x 10(8) vs. 1.4 x 10(8), p less than .001). Additionally, it offers a selectable volume of the concentrate and a better control of the ACD infusion. The Spectra standard procedure needs more ACD, resulting in more citrate dependent donor reactions (5% vs. 1%). In conclusion, the Spectra system shows a more efficient and pure platelet separation compared with the CS 3000.
authors.affiliation: Red Cross Blood Bank, University of Ulm.
authors.forename: M
authors.initials: M
authors.lastname: Wiesneth
authors.forename: J
authors.initials: J
authors.lastname: Freudenberg
authors.forename: S
authors.initials: S
authors.lastname: Platow
authors.forename: J
authors.initials: J
authors.lastname: Kalinova
authors.forename: M
authors.initials: M
authors.lastname: Vogel
authors.forename: B
authors.initials: B
authors.lastname: Kubanek
mesh_terms: D000293:Adolescent; D000328:Adult; D016913:Blood Component Transfusion / Q000295:instrumentation; D001782:Blood Donors; D004867:Equipment Design; D005260:Female; D006452:Hemoglobinometry / Q000295:instrumentation; D006801:Humans; D007958:Leukocyte Count / Q000295:instrumentation; D008297:Male; D008875:Middle Aged; D010976:Platelet Count / Q000295:instrumentation*; D010983:Plateletpheresis / Q000295:instrumentation*