title: [Prospective randomized study on the comparative effect between 10% HES 200/0.5 and 6% HES 200/0.5 in patients with hearing loss].
abstract: Two good comparable groups of patients (group 1 treated with 10% HES 200/0.5 + Naftidrofuryl; and group 2 treated with 6% HES 200/0.5 + Naftidrofuryl) with sudden hearing loss were compared with respect to their hearing recovery, hemorheological parameters and intravasal detectable HES fraction. The results showed an overall improvement of the hemorheological features. No difference between the two groups could be found wether in the hearing improvement nor the investigated parameters. We therefore conclude, that HES 6% is a good alternative to HES 10% for hemodilution therapy in cochleo-vestibular disorders.
authors.affiliation: Universitäts-Hals-Nasen-Ohrenklinik Graz.
authors.forename: G
authors.initials: G
authors.lastname: Friedrich
authors.forename: E
authors.initials: E
authors.lastname: Ott
mesh_terms: D000328:Adult; D000368:Aged; D001299:Audiometry / Q000379:methods; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D003639:Hearing Loss, Sudden / Q000188:drug therapy*; D006438:Hemodilution / Q000379:methods*; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives; D008297:Male; D008875:Middle Aged; D009257:Nafronyl / Q000008:administration & dosage*; D011446:Prospective Studies; D014724:Vestibular Function Tests
chemical_list: D006895:Hydroxyethyl Starch Derivatives; D009257:Nafronyl
vernacular_title: Prospektiv randomisierte Studie zum Wirkungsvergleich zwischen 10% HES 200/0.5 und 6% HES 200/0.5 bei Hörsturzpatienten.