Short-term effect of kainic acid administration and its dependence on the circadian rhythm on cytoplasmic RNA content in neurons of the hypothalamus of mice.
Kainic acid in a dose of 12 micrograms/g given 1 hour before decapitation strongly modifies the content of cytoplasmic RNA, as determined cytophotometrically, in neurons of the supraoptic, paraventricular, and arcuate nuclei of the hypothalamus of adult mice. This stimulatory action of kainic acid was strongest during the night hours when the control animals exhibited the lowest amounts.
Srebro
Z
Z
Department of Biology, Medical Academy, Kraków, Poland.
Lach
H
H
D000818:Animals; D002940:Circadian Rhythm; D003593:Cytoplasm / Q000378:metabolism; D007031:Hypothalamus / Q000378:metabolism*; D007608:Kainic Acid / Q000494:pharmacology*; D008297:Male; D051379:Mice; D012313:RNA / Q000378:metabolism*
D012313:RNA; D007608:Kainic Acid