Obstetric complications in a patient with Bernard-Soulier syndrome.
We describe the obstetric complications and management of a patient with Bernard-Soulier syndrome. Severe bleeding at the time of delivery and delayed postpartum hemorrhage were prominent features of her pregnancies. Further complicating this woman's pregnancies was the development of antibodies to platelet glycoprotein IB/IX, leading to neonatal alloimmune thrombocytopenia.
Peng
T C
TC
Department of Obstetrics and Gynecology, Johns Hopkins University School of Medicine, Baltimore, MD.
Kickler
T S
TS
Bell
W R
WR
Haller
E
E
D000328:Adult; D015119:Aminocaproic Acid / Q000627:therapeutic use; D001606:Bernard-Soulier Syndrome / Q000150:complications* / Q000276:immunology; D005260:Female; D006801:Humans; D007112:Immunity, Maternally-Acquired; D010980:Platelet Membrane Glycoproteins / Q000276:immunology; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic; D013921:Thrombocytopenia / Q000517:prevention & control*; D005719:gamma-Globulins / Q000627:therapeutic use
D010980:Platelet Membrane Glycoproteins; D005719:gamma-Globulins; D015119:Aminocaproic Acid