[Interferon activates DNA repair genes in UV-irradiated human cells].
Unscheduled DNA synthesis in human fibroblasts pretreated with natural and recombinant interferons was studied by scintillated radiometry. UDS was increased in fibroblasts pretreated 7 days before UV-irradiation. Newly synthesized proteins induced in cells after interferon treatment were compared with heat shock proteins.
Sinel'shchikova
T A
TA
Gubitskaia
E G
EG
Akhmatullina
N B
NB
Tashenova
A A
AA
Zasukhina
G D
GD
D002478:Cells, Cultured; D004260:DNA Repair / Q000187:drug effects / Q000235:genetics*; D005347:Fibroblasts / Q000187:drug effects / Q000502:physiology / Q000528:radiation effects; D006360:Heat-Shock Proteins / Q000737:chemistry; D006801:Humans; D007372:Interferons / Q000494:pharmacology*; D014176:Protein Biosynthesis; D011506:Proteins / Q000737:chemistry; D014466:Ultraviolet Rays
D006360:Heat-Shock Proteins; D011506:Proteins; D007372:Interferons
Interferon aktiviruet geny reparatsii DNK v UF-obluchennykh kletkakh cheloveka.