Fetal thyroid-stimulating hormone response to maternal administration of thyrotropin-releasing hormone.
Thyroid-stimulating hormone was measured in fetal blood samples obtained by cordocentesis before and after blood transfusion in Rh-affected pregnancies at 25 to 37 weeks' gestation. In eight of 26 study subjects thyrotropin-releasing hormone was given to the mothers immediately after the pretransfusion samples were obtained. In this group the fetal thyroid-stimulating hormone concentrations in the posttransfusion samples were significantly higher than those before the transfusion.
Thorpe-Beeston
J G
JG
Harris Birthright Research Centre for Fetal Medicine, King's College School of Medicine and Dentistry, London, United Kingdom.
Nicolaides
K H
KH
Snijders
R J
RJ
Butler
J
J
McGregor
A M
AM
D001805:Blood Transfusion, Intrauterine; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D005319:Fetal Hemoglobin / Q000032:analysis; D006801:Humans; D008431:Maternal-Fetal Exchange; D010902:Pituitary Gland / Q000187:drug effects; D011247:Pregnancy; D011863:Radioimmunoassay; D013972:Thyrotropin / Q000097:blood*; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology*; D013997:Time Factors; D014470:Umbilical Cord / Q000098:blood supply
D013973:Thyrotropin-Releasing Hormone; D013972:Thyrotropin; D005319:Fetal Hemoglobin