A novel human multi-locus DNA family detected by pJU78 (DF31).
pJU78 is a 2.9-kb cloned human DNA segment derived from Xq24-q26. When used as a hybridization probe, it detects some 25 related sequences dispersed over the genome, including several autosomes and the X and Y chromosomes. Several pJU78-related sequences were chromosomally allocated and five different restriction fragment length polymorphisms detected and partially characterized in population and family studies. This sequence family was not found in non-primate species. The sequence appears to lack CpG-island character and is not detectably expressed in a variety of human tissues.
Peinemann
F
F
Institut für Humangenetik der Universität, Göttingen, Federal Republic of Germany.
Cooper
D N
DN
Grzeschik
K H
KH
Schmidtke
J
J
D000818:Animals; D015139:Blotting, Southern; D002417:Cattle; D002877:Chromosomes, Human; D004247:DNA / Q000097:blood / Q000235:genetics* / Q000302:isolation & purification; D015246:Deoxyribonuclease EcoRI; D019003:Deoxyribonuclease HpaII; D015252:Deoxyribonucleases, Type II Site-Specific; D005260:Female; D006801:Humans; D007962:Leukocytes / Q000737:chemistry; D008099:Liver / Q000737:chemistry; D008297:Male; D005810:Multigene Family; D002679:Pan troglodytes; D010375:Pedigree; D010957:Plasmids; D012150:Polymorphism, Restriction Fragment Length; D015183:Restriction Mapping; D012727:Sex Characteristics
D004247:DNA; D015246:Deoxyribonuclease EcoRI; D019003:Deoxyribonuclease HpaII; D015252:Deoxyribonucleases, Type II Site-Specific