[Pattern analytic investigations of blast cells in myelodysplastic syndrome and secondary acute myeloid leukemia].
Blast-cells in Romanowsky-Giemsa stained bone marrow smears from 14 cases of primary myelodysplastic syndrome which consequently developed an acute myeloid leukemia and 28 cases of primary acute myeloid leukemia were analysed by a computer aided high resolution pattern recognition system. As control we used blast-cells from reactive affected bone marrow. Whereas blast-cell types in MDS and secondary AML showed overlapping features and a heterogenous distribution we could distinguish blasts in primary AML compared to "reactive" blasts. Opposite to this blasts in secondary AML showed no different pattern compared to "reactive" blast.
Baumann
I
I
Pathologisches Institut, Universität Würzburg.
Harms
H
H
Kuse
R
R
Feller
A C
AC
Müller-Hermelink
H K
HK
D000208:Acute Disease; D001853:Bone Marrow / Q000473:pathology*; D006412:Hematopoietic Stem Cells / Q000473:pathology*; D006801:Humans; D007951:Leukemia, Myeloid / Q000209:etiology / Q000473:pathology*; D009190:Myelodysplastic Syndromes / Q000150:complications / Q000473:pathology*; D011379:Prognosis; D013194:Staining and Labeling
Bildanalytische Untersuchungen von Blasten bei myelodysplastischem Syndrom und sekundärer akuter myeloischer Leukämie.