Epitope study and cDNA screening of major surface glycoprotein of Pneumocystis carinii.
Use of monoclonal antibodies against the major glycoprotein of Pneumocystis carinii (P115) implicated the sugar moiety as being strongly antigenic. Furthermore, monoclonal antibodies directed against the peptide portion of P115 were generated by using synthetic oligopeptides after amino acid sequencing was done on P115 proteolytic fragments.
Nakamura
Y
Y
Institute of Medical Science, University of Tokyo, Japan.
Kitada
K
K
Wada
M
M
Saito
M
M
D000595:Amino Acid Sequence; D000911:Antibodies, Monoclonal / Q000276:immunology; D000946:Antigens, Fungal / Q000276:immunology*; D002241:Carbohydrates / Q000276:immunology; D004271:DNA, Fungal; D000939:Epitopes / Q000276:immunology*; D005656:Fungal Proteins / Q000276:immunology*; D015723:Gene Library; D006023:Glycoproteins / Q000276:immunology*; D008969:Molecular Sequence Data; D010455:Peptides / Q000138:chemical synthesis / Q000276:immunology; D011010:Pneumocystis / Q000235:genetics / Q000276:immunology*
D000911:Antibodies, Monoclonal; D000946:Antigens, Fungal; D002241:Carbohydrates; D004271:DNA, Fungal; D000939:Epitopes; D005656:Fungal Proteins; D006023:Glycoproteins; D010455:Peptides