Transient symptomatic subendocardial ischemia during intravenous magnesium sulfate tocolytic therapy.
Although beta-sympathomimetic tocolytic therapy has been associated with transient subendocardial ischemia, magnesium sulfate has rarely been noted to cause acute chest pain and is, in fact, known to improve myocardial perfusion in patients with variant angina. We believe this report represents the first case in which intravenous magnesium sulfate administered as a tocolytic agent caused acute chest pain accompanied by transient electrocardiographic evidence of subendocardial ischemia.
Sherer
D M
DM
Department of Obstetrics and Gynecology, Strong Memorial Hospital, University of Rochester School of Medicine and Dentistry, NY 14642-8668.
Cialone
P R
PR
Abramowicz
J S
JS
Woods
J R
JR
D000328:Adult; D003327:Coronary Disease / Q000139:chemically induced*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008278:Magnesium Sulfate / Q000009:adverse effects*; D011247:Pregnancy; D015145:Tocolysis; D015149:Tocolytic Agents / Q000009:adverse effects*
D015149:Tocolytic Agents; D008278:Magnesium Sulfate