[Hypervolemic hemodilution with medium molecular-weight hydroxyethyl starch: effect of duration of administration on viscoelasticity of blood in IIa and IIb peripheral arterial occlusive disease].
45 consecutive patients suffering from peripheral arterial occlusive disease (PAOD) stage IIa and b were integrated in a study about the effect of hemorheological parameters due to different application times. The patients were divided into 3 subgroups with different application times: group A received the infusion during 2, group B during 4, and group C during 6 hours. The used substance was 500 ml 6% HES 200,000/0.6-0.66. Except elasticity of group A all hemorheological parameters from group A to group C show a decrease after 6 hours, the trend to the same phenomenon could be observed after 24 hours in group B and C, while group A except plasma viscosity showed even a trend to increasing values compared to onset. As a conclusion of these results, long-time application should be preferred.
Költringer
P
P
Neurologische Abteilung, Barmherzige Brüder Eggenberg, Graz, Austria.
Langsteger
W
W
Lind
P
P
Klima
G
G
Pierer
G
G
Reisecker
F
F
Eber
O
O
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001157:Arterial Occlusive Diseases / Q000097:blood / Q000628:therapy*; D001809:Blood Viscosity / Q000187:drug effects* / Q000502:physiology; D001810:Blood Volume / Q000187:drug effects* / Q000502:physiology; D004334:Drug Administration Schedule; D005260:Female; D006400:Hematocrit; D006438:Hemodilution / Q000379:methods*; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000008:administration & dosage*; D007511:Ischemia / Q000097:blood / Q000628:therapy; D007866:Leg / Q000098:blood supply; D008297:Male; D008875:Middle Aged
D006895:Hydroxyethyl Starch Derivatives
Hypervolämische Hämodilution mit mittel-molekularer Hydroxyäthylstärke: Der Einfluss der Applikationsdauer auf die Viskoelastizität des Blutes bei PAVK IIa und IIb.