[Therapy of immune thrombopenia].
Idiopathic thrombocytopenic purpura (ITP) belongs to the family of autoimmune diseases. The term "idiopathic", however, is no longer correct as it is in fact an immunologically-related thrombocytopenia. This is why nowadays it is referred to as immune thrombopenia. Clinically the acute and chronic forms of ITP can be distinguished. We discuss the different forms of treatment based upon data provided by various studies of ITP. If treatment with prednisone or with gammaglobulins fails, or after unsuccessful splenectomy, then alternative experimental therapies may have to be used. Some of these treatments are described with reference to their therapeutic benefit and their function.
Egli
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Medizinische Poliklinik, Universitätsspital Zürich.
D000208:Acute Disease; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001205:Ascorbic Acid / Q000627:therapeutic use; D001327:Autoimmune Diseases / Q000628:therapy; D002648:Child; D002908:Chronic Disease; D003613:Danazol / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007136:Immunoglobulins; D007372:Interferons / Q000627:therapeutic use; D007518:Isoantibodies / Q000627:therapeutic use; D011696:Purpura, Thrombocytopenic / Q000628:therapy*; D012204:Rh-Hr Blood-Group System / Q000276:immunology; D018029:Rho(D) Immune Globulin; D013156:Splenectomy; D005719:gamma-Globulins / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D000970:Antineoplastic Agents; D007136:Immunoglobulins; D007518:Isoantibodies; D012204:Rh-Hr Blood-Group System; D018029:Rho(D) Immune Globulin; D005719:gamma-Globulins; D007372:Interferons; D003613:Danazol; D001205:Ascorbic Acid
Therapie der Immunthrombopenie.