title: Localization of the gene encoding myelin basic protein to mouse chromosome 18E3----4 and rat chromosome 1p11----p12.
abstract: The location of a gene encoding myelin basic protein in rat (MBP) and mouse (Mbp) was determined by in situ hybridization using the mouse Mbp cDNA labeled with biotin-11-dUTP as a specific probe. The localization of biotin signals in the mouse was found on Chromosome 18E2----3. The result is consistent with the previous report that the Mbp gene is located on the distal half of Chromosome 18. In the rat, the signals localized on chromosome 1p11----p12, suggesting homology between mouse Chromosome 18 and the short arm of rat chromosome 1.
authors.affiliation: Institute for Experimental Animals, School of Medicine, Kanazawa University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Koizumi
authors.forename: M
authors.initials: M
authors.lastname: Katsuki
authors.forename: M
authors.initials: M
authors.lastname: Kimura
authors.forename: J
authors.initials: J
authors.lastname: Hayakawa
mesh_terms: D000818:Animals; D002871:Chromosome Banding; D002874:Chromosome Mapping; D015342:DNA Probes; D005796:Genes; D051379:Mice / Q000235:genetics*; D004676:Myelin Basic Protein / Q000235:genetics*; D009693:Nucleic Acid Hybridization; D051381:Rats / Q000235:genetics*
chemical_list: D015342:DNA Probes; D004676:Myelin Basic Protein