title: Fresh osteochondral allografts for post-traumatic defects in the knee. A survivorship analysis.
abstract: Fresh osteochondral allografts were used to repair post-traumatic osteoarticular defects in 92 knees. At the time of grafting, varus or valgus deformities were corrected by upper tibial or supracondylar femoral osteotomies. A survivorship analysis was performed in which failure was defined as the need for a revision operation or the persistence of the pre-operative symptoms. There was a 75% success rate at five years, 64% at ten years and 63% at 14 years. The failure rate was higher for bipolar grafts than for unipolar and the results in patients over the age of 60 years were poor. The outcome did not depend on the sex of the patient and the results of allografts in the medial and lateral compartments of the knee were similar. Careful patient selection, correction of joint malalignment by osteotomy, and rigid fixation of the graft are all mandatory requirements for success. We recommend this method for the treatment of post-traumatic osteochondral defects in the knees of relatively young and active patients.
authors.affiliation: Division of Orthopaedic Surgery, Mount Sinai Hospital, Toronto, Ontario, Canada.
authors.forename: R J
authors.initials: RJ
authors.lastname: Beaver
authors.forename: M
authors.initials: M
authors.lastname: Mahomed
authors.forename: D
authors.initials: D
authors.lastname: Backstein
authors.forename: A
authors.initials: A
authors.lastname: Davis
authors.forename: D J
authors.initials: DJ
authors.lastname: Zukor
authors.forename: A E
authors.initials: AE
authors.lastname: Gross
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016025:Bone Transplantation / Q000379:methods / Q000706:statistics & numerical data; D002102:Cadaver; D002358:Cartilage, Articular / Q000637:transplantation*; D005260:Female; D006085:Graft Survival; D006801:Humans; D007718:Knee Injuries / Q000453:epidemiology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D016019:Survival Analysis; D014184:Transplantation, Homologous