Biosynthesis of P450 products of arachidonic acid in humans: increased formation in cardiovascular disease.
Catella
F
F
Division of Clinical Pharmacology, Vanderbilt University, Nashville, Tennessee 37232.
Lawson
J
J
Braden
G
G
Fitzgerald
D J
DJ
Shipp
E
E
FitzGerald
G A
GA
D015056:1-Methyl-3-isobutylxanthine / Q000494:pharmacology; D019796:15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; D015126:8,11,14-Eicosatrienoic Acid / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology / Q000652:urine; D000789:Angina, Unstable / Q000378:metabolism*; D015906:Angioplasty, Balloon, Coronary; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000378:metabolism*; D005576:Colforsin / Q000494:pharmacology; D000242:Cyclic AMP / Q000494:pharmacology; D000090762:Cytochrome P-450 CYP2J2; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D005260:Female; D006801:Humans; D010105:Oxygenases / Q000378:metabolism; D015539:Platelet Activation / Q000187:drug effects; D011225:Pre-Eclampsia / Q000378:metabolism*; D011247:Pregnancy / Q000378:metabolism; D011450:Prostaglandin Endoperoxides, Synthetic / Q000494:pharmacology; D013917:Thrombin / Q000494:pharmacology
D001095:Arachidonic Acids; D011450:Prostaglandin Endoperoxides, Synthetic; D005576:Colforsin; D016718:Arachidonic Acid; C046783:11,12-epoxy-5,8,14-eicosatrienoic acid; D019796:15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; C050715:8,9-epoxyeicosatrienoic acid; C046782:14,15-epoxy-5,8,11-eicosatrienoic acid; D003577:Cytochrome P-450 Enzyme System; D000242:Cyclic AMP; D010105:Oxygenases; D000090762:Cytochrome P-450 CYP2J2; D013917:Thrombin; D015126:8,11,14-Eicosatrienoic Acid; D015056:1-Methyl-3-isobutylxanthine