title: Embolization of hepatic arteriovenous malformations using radiolabeled and nonradiolabeled polyvinyl alcohol sponge in a patient with hereditary hemorrhagic telangiectasia: case report.
abstract: Polyvinyl alcohol sponge (PVA) radiolabeled with 99mTc-sulfur colloid was used to evaluate a large hepatic arteriovenous malformation (AVM) in a 71-yr-old white female prior to embolization. The patient had hereditary hemorrhagic telangiectasia (Osler-Weber-Rendu) with severe left-to-right shunting through the hepatic AVM which resulted in high-output congestive heart failure. The patient also had severe pulmonary hypertension. Scintigraphic imaging of the embolized radiolabeled PVA particles allowed us to be certain that the particles did not flow through the liver and inadvertently embolize the lungs; with the patient's already poor pulmonary status, embolization could have been fatal.
authors.affiliation: Department of Radiology, University of Utah School of Medicine, Salt Lake City.
authors.forename: J H
authors.initials: JH
authors.lastname: Whiting
authors.forename: K A
authors.initials: KA
authors.lastname: Morton
authors.forename: F L
authors.initials: FL
authors.lastname: Datz
authors.forename: G G
authors.initials: GG
authors.lastname: Patch
authors.forename: F J
authors.initials: FJ
authors.lastname: Miller
mesh_terms: D000368:Aged; D001165:Arteriovenous Malformations / Q000000981:diagnostic imaging* / Q000628:therapy; D016534:Cardiac Output, High / Q000150:complications; D004621:Embolization, Therapeutic; D005260:Female; D006333:Heart Failure / Q000150:complications; D006499:Hepatic Artery / Q000002:abnormalities; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications; D011145:Polyvinyls / Q000627:therapeutic use*; D011877:Radionuclide Imaging; D013671:Technetium Tc 99m Sulfur Colloid; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000150:complications*
chemical_list: D011145:Polyvinyls; C026699:ivalon sponge; D013671:Technetium Tc 99m Sulfur Colloid