title: NMR studies of an FK-506 analogue, [U-13C]ascomycin, bound to FKBP: conformation and regions of ascomycin involved in binding.
authors.affiliation: Pharmaceutical Discovery Division, Abbott Laboratories, Abbott Park, Illinois 60064.
authors.forename: A M
authors.initials: AM
authors.lastname: Petros
authors.forename: R T
authors.initials: RT
authors.lastname: Gampe
authors.forename: G
authors.initials: G
authors.lastname: Gemmecker
authors.forename: P
authors.initials: P
authors.lastname: Neri
authors.forename: T F
authors.initials: TF
authors.lastname: Holzman
authors.forename: R
authors.initials: R
authors.lastname: Edalji
authors.forename: J
authors.initials: J
authors.lastname: Hochlowski
authors.forename: M
authors.initials: M
authors.lastname: Jackson
authors.forename: J
authors.initials: J
authors.lastname: McAlpine
authors.forename: J R
authors.initials: JR
authors.lastname: Luly
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry*; D001665:Binding Sites; D002352:Carrier Proteins / Q000737:chemistry*; D007166:Immunosuppressive Agents / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D016559:Tacrolimus / Q000031:analogs & derivatives; D022021:Tacrolimus Binding Proteins; D014961:X-Ray Diffraction
chemical_list: D000900:Anti-Bacterial Agents; D002352:Carrier Proteins; D007166:Immunosuppressive Agents; C058028:immunomycin; D022021:Tacrolimus Binding Proteins; D016559:Tacrolimus