Verapamil versus lithium in acute mania.
Twenty acutely manic patients were studied in a double-blind randomized trial comparing verapamil with lithium. The Petterson Mania Scale, the Brief Psychiatric Rating Scale (BPRS), and the Clinical Global Impression (CGI) were administered before treatment and weekly during 4 weeks of treatment to evaluate response to verapamil and lithium. Both treatment groups improved significantly, and there were no significant overall differences between treatments.
Garza-Treviño
E S
ES
University of Texas Health Science Center, San Antonio.
Overall
J E
JE
Hollister
L E
LE
D000208:Acute Disease; D000328:Adult; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000523:psychology; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D016651:Lithium Carbonate / Q000627:therapeutic use*; D008297:Male; D011569:Psychiatric Status Rating Scales; D014700:Verapamil / Q000627:therapeutic use*
D016651:Lithium Carbonate; D014700:Verapamil