Penetration power of antiseptic creams ("in vitro" model with pig skin).
By means of an "in vitro" method using pig skin, the authors determine the penetration power of some antiseptic creams in order out the most effective one from this point of view in the treatment of subscar-located infections. The following antiseptic creams were studied: 1% Silver Sulfadiazine, 1% Silver Sulfadiazine with 2.2% Cerium Nitrate, 2.2% Cerium Nitrate, 10% Iodine Povidone, 0.2% Nitrofurazone 0.1%, 0.5% and 1% Chlorhexidine. These products were faced with 17 microorganisms isolated from burn wounds and a control one. The minimal inhibitory concentrations (MIC) obtained after passing through the penetration power of some antiseptic creams in order to find out the most effective one from this point of view in the treatment of subscar-located infections.
Garcia Torres
V
V
Burns Unit, Hospital La Paz, Madrid, Spain.
Herruzo
R
R
Santos Heredero
F X
FX
Lenguas
F
F
Martinez Ratero
S
S
del Fresno
C
C
D000818:Animals; D000891:Anti-Infective Agents, Local / Q000378:metabolism* / Q000494:pharmacology; D002056:Burns / Q000382:microbiology; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests; D009824:Ointments; D012869:Skin Absorption; D013552:Swine
D000891:Anti-Infective Agents, Local; D009824:Ointments