title: Detection of internal carotid artery stenosis: comparison of MR angiography, color Doppler sonography, and arteriography.
abstract: Findings of two-dimensional time-of-flight magnetic resonance (MR) angiography projection angiograms were prospectively compared with those of color Doppler sonography by using angiography as a standard in 23 consecutive patients (42 carotid bifurcations) to evaluate their utility in determining the presence of carotid artery stenosis. MR angiography helped detect 50% or greater lumen diameter stenosis (sensitivity, 0.96; specificity, 0.64). Color Doppler sonography with 1.25 m/sec peak systolic velocity as a threshold had a sensitivity of 0.96 and a specificity of 0.71. Statistical analysis showed a correlation between percentage of lumen diameter narrowing and the length of the zone of signal intensity loss with MR angiography (r = .69; P less than .0001). A stronger relationship was obtained between angiographic narrowing and peak systolic velocity derived from color Doppler sonography (r = .80; P less than .0001). Two-dimensional time-of-flight MR angiography displayed as projection angiograms and combined with carotid artery and combined with carotid artery sonography is a useful approach for helping detect and potentially grade the severity of stenoses of the carotid artery.
authors.affiliation: Department of Radiology, Brigham and Women's Hospital, Boston, MA 02115.
authors.forename: J F
authors.initials: JF
authors.lastname: Polak
authors.forename: R L
authors.initials: RL
authors.lastname: Bajakian
authors.forename: D H
authors.initials: DH
authors.lastname: O'Leary
authors.forename: M R
authors.initials: MR
authors.lastname: Anderson
authors.forename: M C
authors.initials: MC
authors.lastname: Donaldson
authors.forename: F A
authors.initials: FA
authors.lastname: Jolesz
mesh_terms: D000368:Aged; D002343:Carotid Artery, Internal / Q000473:pathology; D016893:Carotid Stenosis / Q000175:diagnosis* / Q000453:epidemiology; D002533:Cerebral Angiography; D004453:Echoencephalography / Q000379:methods; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D014465:Ultrasonics