Association of HLA-DQw4 with IgA nephropathy in the Japanese population.
We have studied HLA-A, B, DR and DQ phenotypes in 50 Japanese patients with IgA nephropathy. The antigen frequency of HLA-DQw4, which is known to be associated with DR4/Dw15 specificity, was increased in the patient group as well as in those of B35 and DR4. The increase of DQw4 (36.0%) was significantly different from that of national controls (corrected p less than 0.004).
Hiki
Y
Y
Department of Medicine, School of Nursing, Kitasato University, Kanagawa, Japan.
Kobayashi
Y
Y
Ookubo
M
M
Obata
F
F
Kashiwagi
N
N
D000328:Adult; D000939:Epitopes / Q000276:immunology; D005260:Female; D005922:Glomerulonephritis, IGA / Q000276:immunology*; D006683:HLA-DQ Antigens / Q000032:analysis*; D006801:Humans; D007564:Japan; D008297:Male; D010641:Phenotype
D000939:Epitopes; D006683:HLA-DQ Antigens; C060029:HLA-DQ4 antigen