Effects of FK 506 and cyclosporine on T-cell tolerance: inhibition of a "protective" mechanism that regulates activation-induced apoptosis in developing thymocytes.
McCarthy
S A
SA
Department of Surgery, University of Pittsburgh School of Medicine, Pennsylvania.
Mainwaring
M S
MS
Cairns
J S
JS
D000818:Animals; D000001:Calcimycin / Q000494:pharmacology; D016923:Cell Death / Q000187:drug effects*; D002478:Cells, Cultured; D016572:Cyclosporine / Q000494:pharmacology*; D004247:DNA / Q000032:analysis; D007108:Immune Tolerance / Q000187:drug effects*; D051379:Mice; D008810:Mice, Inbred C57BL; D013601:T-Lymphocytes / Q000166:cytology / Q000187:drug effects / Q000276:immunology*; D016559:Tacrolimus / Q000494:pharmacology*; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology
D000001:Calcimycin; D016572:Cyclosporine; D004247:DNA; D013755:Tetradecanoylphorbol Acetate; D016559:Tacrolimus