Retrograde adriamycin sensory ganglionectomy: novel approach for the treatment of intractable pain.
Selective sensory ganglionectomy by means of retrograde suicide transport of adriamycin was performed on 3 patients with neuropathic pain in the areas of the trigeminal and intercostal nerves, producing significant pain relief, particularly from hyperalgesic pain. Adriamycin ganglionectomy is considered as a less invasive and highly selective pain treatment, which may possibly become an alternative for surgical ganglionectomy or rhizotomy.
Kato
S
S
Division of Neurosurgery, Tohoku University School of Medicine, Sendai, Japan.
Otsuki
T
T
Yamamoto
T
T
Iwasaki
Y
Y
Yoshimoto
T
T
D000368:Aged; D000369:Aged, 80 and over; D001370:Axonal Transport / Q000502:physiology; D004317:Doxorubicin / Q000008:administration & dosage* / Q000493:pharmacokinetics; D005260:Female; D006801:Humans; D007267:Injections; D007367:Intercostal Nerves / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D009437:Neuralgia / Q000188:drug therapy*; D010148:Intractable Pain / Q000188:drug therapy*; D012668:Trigeminal Ganglion / Q000187:drug effects*; D014277:Trigeminal Neuralgia / Q000188:drug therapy*
D004317:Doxorubicin