title: Histopathological effects of environmental pollutants beta-HCH and methyl mercury on reproductive organs in freshwater fish.
abstract: From various environmental pollutants studied so far, specific effects on the reproductive system of small fish species Poecilia reticulata (guppy) and Oryzias latipes (medaka) were noted in the case of beta-hexachlorocyclohexane (induction of vitellogenesis and hermaphroditism, both indicative of estrogenic activity; 32 micrograms/l) and methyl mercury (impaired spermatogenesis; 1.8 micrograms/l). The latter effect was attributed to a disturbance of mitosis.
authors.affiliation: Laboratory for Pathology, National Institute of Public Health and Environmental Protection, Bilthoven, The Netherlands.
authors.forename: P W
authors.initials: PW
authors.lastname: Wester
mesh_terms: D000818:Animals; D005260:Female; D005393:Fish Diseases / Q000139:chemically induced; D005618:Fresh Water; D005835:Genitalia / Q000187:drug effects*; D057850:Hermaphroditic Organisms; D001556:Hexachlorocyclohexane / Q000633:toxicity*; D007536:Isomerism; D008297:Male; D008767:Methylmercury Compounds / Q000633:toxicity*; D009990:Oryzias / Q000033:anatomy & histology*; D011036:Poecilia / Q000033:anatomy & histology*; D019849:Sex Determination Processes / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary; D013091:Spermatogenesis / Q000187:drug effects; D014818:Vitellogenesis / Q000187:drug effects; D014874:Water Pollutants, Chemical / Q000633:toxicity*
chemical_list: D008767:Methylmercury Compounds; D014874:Water Pollutants, Chemical; D001556:Hexachlorocyclohexane; C023888:beta-hexachlorocyclohexane