title: [Monoclonal antibodies to antigens of the Rh system].
abstract: For the development of monoclonal antibodies, which are useful for typing of Rh-system antigens, human monoclonal antibodies are needed. We have established a method for raising human monoclonal antibodies using EBV-transformation and subsequent stabilisation by fusing with mouse myeloma or heteromyeloma cell-lines. Using this method, we have produced several clones reacting with the D antigen which can be used for typing purposes as well as for research purposes to differentiate epitopes and categories.
authors.affiliation: Biotest AG, Forschugszentrum, Offenbach.
authors.forename: H H
authors.initials: HH
authors.lastname: Sonneborn
authors.forename: M
authors.initials: M
authors.lastname: Ernst
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000918:Antibody Specificity / Q000276:immunology; D002461:Cell Line, Transformed; D006801:Humans; D051379:Mice; D012204:Rh-Hr Blood-Group System / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D012204:Rh-Hr Blood-Group System
vernacular_title: Monoklonale Antikörper gegen Antigene des Rh-Systems.