title: [Evaluation of fetal antigenic stimulation in physiological and complicated pregnancy].
abstract: Fetal hemoglobin and trophoblastic beta 1-globulin levels have been determined in women with normal and complicated pregnancy in order to evaluate the rates of fetal antigenic stimulation. It was demonstrated that trophoblastic beta 1-globulin may not exactly represent fetal antigenic structures, but it is a marker of functional feto-placental activity. An elevated percentage of HbF in blood in threatened+ abortion and early toxemia of pregnancy confirmed feasibility of using it as an indirect marker of fetal antigenic stimulation and permeability of the fetoplacental barrier.
authors.forename: O V
authors.initials: OV
authors.lastname: Osadchaia
authors.forename: V V
authors.initials: VV
authors.lastname: Shabadash
mesh_terms: D000328:Adult; D000941:Antigens / Q000276:immunology*; D001609:Beta-Globulins / Q000276:immunology*; D005260:Female; D005319:Fetal Hemoglobin / Q000276:immunology*; D006801:Humans; D011225:Pre-Eclampsia / Q000097:blood* / Q000276:immunology; D011247:Pregnancy / Q000097:blood* / Q000276:immunology; D011262:Pregnancy Trimester, Second; D011268:Pregnancy-Specific beta 1-Glycoproteins / Q000276:immunology*; D014327:Trophoblasts / Q000276:immunology*
chemical_list: D000941:Antigens; D001609:Beta-Globulins; D011268:Pregnancy-Specific beta 1-Glycoproteins; D005319:Fetal Hemoglobin
vernacular_title: Otsenka fetal'noĭ antigennoĭ stimuliatsii pri fiziologicheski protekaiushcheĭ i oslozhnennoĭ beremennosti.