title: [Polyfunctional inhibitors of proteolytic enzymes in the therapy of patients with chronic purulent maxillary sinusitis].
abstract: Using clinical and biochemical data, the efficacy of the topical application of kontrikal, a polyfunctional inhibitor of proteinases, for the therapy of chronic purulent sinusitis is discussed. The drug was found to reduce the activity of proteolytic enzymes in the purulent exudate from the maxillary sinus. As compared with the controls (27 patients), the treated group (38 patients) showed a rapid disappearance of clinical manifestations, shortening of the therapeutic period, increase of proteinase inhibitors and decrease of protein in the exudate.
authors.forename: D I
authors.initials: DI
authors.lastname: Zabolotnyĭ
authors.forename: K N
authors.initials: KN
authors.lastname: Veremeenko
authors.forename: N N
authors.initials: NN
authors.lastname: Kazimirko
authors.forename: I E
authors.initials: IE
authors.lastname: Raĭko
mesh_terms: D000293:Adolescent; D000328:Adult; D007611:Aprotinin / Q000627:therapeutic use*; D002908:Chronic Disease; D006801:Humans; D015523:Maxillary Sinusitis / Q000188:drug therapy*; D008875:Middle Aged; D011480:Protease Inhibitors / Q000627:therapeutic use*; D013492:Suppuration
chemical_list: D011480:Protease Inhibitors; D007611:Aprotinin
vernacular_title: Primenenie polifunktsional'nykh ingibitorov proteoliticheskikh fermentov v lechenii bol'nykh khronicheskim gnoĭnym gaĭmoritom.