title: [Erythrocytic immunoreagents for diagnosing autoimmune disorders of the pancreas].
abstract: Amidol sensitization of formalin-treated sheep red blood cells was found to be the optimal method for the preparation of an erythrocytic diagnostic agent from the summary antigen of the pancreas. Organ specificity of serum antibodies detection with the use of the developed diagnostic agent was provided by preliminary adsorption of the tested sera with rhesus-positive human red cells, group IV (AB). Use of this diagnostic agent in the neutralization test permitted a highly specific detection of the pancreatic antigen. Antigen-specific lymphocytes detectable in the indirect rosette-formation test with the erythrocytic diagnostic agent from the pancreatic summary antigen, based on chicken red cells were found highly specific.
authors.forename: K V
authors.initials: KV
authors.lastname: Kim
authors.forename: P N
authors.initials: PN
authors.lastname: Deriabin
authors.forename: B V
authors.initials: BV
authors.lastname: Karal'nik
mesh_terms: D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology*; D006801:Humans; D010182:Pancreatic Diseases / Q000175:diagnosis* / Q000276:immunology
vernacular_title: Eritrotsitarnye immunoreagenty dlia diagnostiki autoimmunnykh povrezhdeniĭ podzheludochnoĭ zhelezy.