Characterization of a novel human papillomavirus DNA in the cervical carcinoma cell line ME180.
The human cervical carcinoma cell line ME180 was examined for human papillomavirus (HPV) DNA and RNA. The integrated DNA of a presumably new HPV type showing a relationship closer to HPV39 than to HPV18 was cloned and sequenced. HPV sequences from the E6-E7-E1 region are expressed as poly(A)+ RNAs.
Reuter
S
S
Projektgruppe Angewandte Tumorvirologie, Deutsches Krebsforschungszentrum, Heidelberg, Germany.
Delius
H
H
Kahn
T
T
Hofmann
B
B
zur Hausen
H
H
Schwarz
E
E
D001483:Base Sequence; D002460:Cell Line; D003001:Cloning, Molecular; D004279:DNA, Viral / Q000235:genetics / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D027383:Papillomaviridae / Q000235:genetics / Q000302:isolation & purification*; D011061:Poly A / Q000235:genetics; D012313:RNA / Q000235:genetics; D012333:RNA, Messenger; D015183:Restriction Mapping; D002583:Uterine Cervical Neoplasms / Q000382:microbiology*
D004279:DNA, Viral; D012333:RNA, Messenger; D011061:Poly A; D012313:RNA