The interaction between cells in different phases of the cell cycle and aminocarb.
Synchronous cultures of Chlamydomonas segnis Ettl. were treated with aminocarb (0.5, 5.0, 10.0, or 50.0 micrograms ml-1) at each specific phase of the cell cycle, namely, G1, S, G2, and M phases. The subsequent effects of some macromolecular products were assayed at the end of the M phase. Aminocarb treatments of 0.5 microgram ml-1 were at the no effects level on the parameters monitored. However, the higher concentrations of aminocarb tested, namely, 5, 10, and 50 micrograms ml-1, dramatically affected not only macromolecular syntheses but also some cell cycle events. Algistatic and algicidal effects were obtained with some treatments.
Dechacin
C
C
Department of Biology, University of Ottawa, Ontario, Canada.
Weinberger
P
P
Czuba
M
M
D002219:Carbamates / Q000633:toxicity*; D002241:Carbohydrates / Q000096:biosynthesis; D002453:Cell Cycle / Q000187:drug effects*; D002696:Chlamydomonas / Q000378:metabolism / Q000502:physiology*; D004247:DNA / Q000096:biosynthesis; D007306:Insecticides / Q000633:toxicity*; D048448:Phenylcarbamates; D010940:Plant Proteins / Q000096:biosynthesis; D012313:RNA / Q000096:biosynthesis
D002219:Carbamates; D002241:Carbohydrates; D007306:Insecticides; D048448:Phenylcarbamates; D010940:Plant Proteins; D012313:RNA; C006511:aminocarb; D004247:DNA