title: [Electrochemotherapy, a new antitumor treatment: first clinical trial].
abstract: Electrochemotherapy (ECT) is a new antitumor treatment which consists in delivering electric pulses to the tumor some minutes after an intravenous injection of bleomycin. We report here the first clinical trial of ECT, applied to patients with permeation nodules of head and neck squamous carcinomas. ECT was well tolerated by patients, no serious incident occurred and a clear antitumor efficiency was found.
authors.affiliation: Unité de Biochimie-Enzymologie de l'I.G.R., U.R.A. n. 147, C.N.R.S., U140 I.N.S.E.R.M., Institut Gustave-Roussy, P.R.I.I., Villejuif.
authors.forename: L M
authors.initials: LM
authors.lastname: Mir
authors.forename: M
authors.initials: M
authors.lastname: Belehradek
authors.forename: C
authors.initials: C
authors.lastname: Domenge
authors.forename: S
authors.initials: S
authors.lastname: Orlowski
authors.forename: B
authors.initials: B
authors.lastname: Poddevin
authors.forename: J
authors.initials: J
authors.lastname: Belehradek
authors.forename: G
authors.initials: G
authors.lastname: Schwaab
authors.forename: B
authors.initials: B
authors.lastname: Luboinski
authors.forename: C
authors.initials: C
authors.lastname: Paoletti
mesh_terms: D001761:Bleomycin / Q000008:administration & dosage* / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000628:therapy*; D004599:Electric Stimulation Therapy / Q000379:methods; D004563:Electrochemistry; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology / Q000628:therapy*; D009959:Oropharyngeal Neoplasms / Q000473:pathology / Q000628:therapy*; D012878:Skin Neoplasms / Q000556:secondary
chemical_list: D001761:Bleomycin
vernacular_title: L'électrochimiothérapie, un nouveau traitement antitumoral: premier essai clinique.