Species differences in the distribution and coexistence ratio of serotonin and substance P in the monkey, cat, rat and chick spinal cord.
Serotoninergic raphe-spinal motor neuron projections exhibit wide species differences in both innervation pattern and coexistence of serotonin and substance P. The coexistence ratios vary widely ranging from more than 80% (rat) to less than 1% (chick). Serotonin and substance P positive fibers are also unevenly distributed in the ventral horn of different species: dense clusters of serotonin and substance P positive fibers were preferentially located in the motor neuron pools of extensor muscles of the hip joint (chick) as well as antigravity muscles of the forelimb (cat and rat).
Okado
N
N
Department of Anatomy, University of Tsukuba, Ibaraki, Japan.
Matsukawa
M
M
Noritake
S
S
Ozaki
S
S
Hamada
S
S
Arita
M
M
Kudo
N
N
D000818:Animals; D002415:Cats; D002645:Chickens; D000882:Haplorhini; D007150:Immunohistochemistry; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000378:metabolism*; D013045:Species Specificity; D013116:Spinal Cord / Q000378:metabolism*; D013373:Substance P / Q000378:metabolism*; D014018:Tissue Distribution
D012701:Serotonin; D013373:Substance P