title: [Pattern analytic investigations of blast cells in myelodysplastic syndrome and secondary acute myeloid leukemia].
abstract: Blast-cells in Romanowsky-Giemsa stained bone marrow smears from 14 cases of primary myelodysplastic syndrome which consequently developed an acute myeloid leukemia and 28 cases of primary acute myeloid leukemia were analysed by a computer aided high resolution pattern recognition system. As control we used blast-cells from reactive affected bone marrow. Whereas blast-cell types in MDS and secondary AML showed overlapping features and a heterogenous distribution we could distinguish blasts in primary AML compared to "reactive" blasts. Opposite to this blasts in secondary AML showed no different pattern compared to "reactive" blast.
authors.affiliation: Pathologisches Institut, Universität Würzburg.
authors.forename: I
authors.initials: I
authors.lastname: Baumann
authors.forename: H
authors.initials: H
authors.lastname: Harms
authors.forename: R
authors.initials: R
authors.lastname: Kuse
authors.forename: A C
authors.initials: AC
authors.lastname: Feller
authors.forename: H K
authors.initials: HK
authors.lastname: Müller-Hermelink
mesh_terms: D000208:Acute Disease; D001853:Bone Marrow / Q000473:pathology*; D006412:Hematopoietic Stem Cells / Q000473:pathology*; D006801:Humans; D007951:Leukemia, Myeloid / Q000209:etiology / Q000473:pathology*; D009190:Myelodysplastic Syndromes / Q000150:complications / Q000473:pathology*; D011379:Prognosis; D013194:Staining and Labeling
vernacular_title: Bildanalytische Untersuchungen von Blasten bei myelodysplastischem Syndrom und sekundärer akuter myeloischer Leukämie.