Inhibition of drug metabolism in rat and human liver microsomes by FK 506 and cyclosporine.
Moochhala
S M
SM
Department of Pharmacology, National University of Singapore.
Lee
E J
EJ
Earnest
L
L
Wong
J Y
JY
Ngoi
S S
SS
D000818:Animals; D016572:Cyclosporine / Q000494:pharmacology*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D011374:Progesterone / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values; D016559:Tacrolimus / Q000494:pharmacology*
D007527:Isoenzymes; D011374:Progesterone; D016572:Cyclosporine; D003577:Cytochrome P-450 Enzyme System; D016559:Tacrolimus