[Mobilization of leukocytes during sub-maximal dynamic exercise].
Increase of blood leucocytes induced by a dynamic exercise has been studied in 10 adult male subjects (age: 22 +/- 2 years; body weight 73 +/- 10 kg; VO2max: 54 +/- 8 ml O2/kg.min. The exercise consisted of a 20 minutes test on a cycle ergometer at a work rate eliciting a total energy expenditure roughly equal to 80% of the maximal aerobic power (80% VO2max). During exercise the absolute number of circulating leucocytes (n Leu) increased significantly toward a maximal value reached in most cases at the end of exercise. The maximal values of n Leu--expressed as percentage of n Leu measured at rest--in the different blood leucocyte types (monocytes:n Mono; granulocytes:n GR; natural killer cells:n NK) and lymphocyte subsets (lymphocytes:n LY; lymphocytes T:n T; lymphocytes B:n B; lymphocytes T helper:n T4; lymphocytes T suppressor:n T8)--were as follows:n Mono:240%; n GR:170%; n NK:490%; n LY:220%; n T:200%; n B:190%; n T4:140%; n T8:190%. With the exception of n GR, n Leu decreased during recovery at a rate depending on the leucocyte type. The n T4/n T8 ratio, equal to 1 at rest, was reduced by about 40% during exercise. This ratio rose after exercise and reached a value equal to that measured at rest after 20 minutes recovery. In agreement with FERRY (1989), we concluded that exercise is accompanied by a selective mobilization of the different leucocyte types. The magnitude of this phenomenon and the kinetics of n Leu recuperation depend on cell types.
Camus
G
G
Laboratoire de physiologie humaine appliquée, ISEP, Sart Tilman, Liège.
Sondag
D
D
Maggipinto
J
J
Pincemail
J
J
Plumier
A F
AF
Feron
F
F
Juchmes-Ferir
A
A
Duchateau
J
J
Lamy
M
M
Deby-Dupont
G
G
D000328:Adult; D015444:Exercise / Q000502:physiology*; D006098:Granulocytes; D006801:Humans; D007694:Killer Cells, Natural; D007958:Leukocyte Count; D016131:Lymphocyte Subsets; D008297:Male; D009000:Monocytes
Mobilisation des leucocytes lors de l'exercice dynamique sous-maximum.