[Hemodilution in acute arterial circulatory disorders of the retina].
20 patients (age: 68 +/- 9 years) with an acute central artery obstruction of the retina were examined in a prospective study. All patients received a hyper- or isovolemic hemodilution depending on the haematocrit value for a period of 10 days. Clinical, hemodynamical and rheological data of these patients were recorded before therapy, after 10 days and after 6 weeks. Under this therapy, 10 patients presented an improved central vision by 2 or more stages. The degree of the distributed circulation can be determined by means of the arteriovenous passage time (AVP) and the dye bolus velocity (MDV). Compared to a control group, a significantly increased arterious-venous passage time and decreased dye bolus velocity can be observed initially. The values after 10 days of therapy and after 6 weeks were significantly improved (p less than 0.01) compared to the initial values.
Arend
O
O
Universitäts Augenklinik, RWTH Aachen, BRD.
Hoberg
A
A
Bertram
B
B
Reim
M
M
Wolf
S
S
D000368:Aged; D000369:Aged, 80 and over; D001809:Blood Viscosity / Q000187:drug effects / Q000502:physiology; D003131:Combined Modality Therapy; D004305:Dose-Response Relationship, Drug; D004903:Erythrocyte Aggregation / Q000187:drug effects / Q000502:physiology; D005260:Female; D005451:Fluorescein Angiography; D006400:Hematocrit; D006438:Hemodilution / Q000379:methods*; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D010431:Pentoxifylline / Q000008:administration & dosage; D011446:Prospective Studies; D015356:Retinal Artery Occlusion / Q000097:blood / Q000628:therapy*; D014792:Visual Acuity / Q000187:drug effects / Q000502:physiology
D006895:Hydroxyethyl Starch Derivatives; D010431:Pentoxifylline
Hämodilution bei akuten arteriellen Durchblutungsstörungen der Retina.