Lymphocyte trafficking in inflamed liver.
Cell-mediated immune reactions occurring in liver diseases involve infiltration of inflammatory cells into the hepatic parenchyma. Almost nothing is known about cellular and molecular mechanisms regulating this leukocyte traffic during the afferent and efferent arms of the hepatic immune response. This overview emphasizes that various liver parenchymal cells appear to participate actively in the development of the inflammatory response.
Volpes
R
R
Department of Pathology, University Hospital Sint-Rafaël, Catholic University of Leuven, Belgium.
van den Oord
J J
JJ
Desmet
V J
VJ
D015703:Antigens, CD / Q000502:physiology; D015214:Antigens, Differentiation, Myelomonocytic / Q000502:physiology; D018826:CD13 Antigens; D002448:Cell Adhesion; D015815:Cell Adhesion Molecules / Q000502:physiology; D002465:Cell Movement; D019040:E-Selectin; D004730:Endothelium, Vascular / Q000502:physiology; D006505:Hepatitis / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D007249:Inflammation / Q000503:physiopathology; D018799:Intercellular Adhesion Molecule-1; D019041:L-Selectin; D008214:Lymphocytes / Q000502:physiology*; D016201:Receptors, Lymphocyte Homing / Q000502:physiology; D019010:Vascular Cell Adhesion Molecule-1
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D015815:Cell Adhesion Molecules; D019040:E-Selectin; D016201:Receptors, Lymphocyte Homing; D019010:Vascular Cell Adhesion Molecule-1; D018799:Intercellular Adhesion Molecule-1; D019041:L-Selectin; D018826:CD13 Antigens