Pathologic fracture associated with amyloid deposition in the bone of a chronic hemodialysis patient. A case report.
A 63-year-old male who had been on hemodialysis for 14 years developed extensive amyloid deposition in the femoral head and neck that, after a fall, resulted in a femoral neck fracture. The plasma level of beta 2-microglobulin in this patient was elevated, and bone specimens from the fracture site demonstrated positive Congo-red staining, suggesting an association with amyloid deposition.
Tateishi
H
H
Department of Orthopaedic Surgery, Hyogo College of Medicine, Nishinomiya, Japan.
Maeda
M
M
Yoh
K
K
Nakano
T
T
Nakano
K
K
D000686:Amyloidosis / Q000097:blood / Q000150:complications* / Q000209:etiology / Q000473:pathology; D005265:Femoral Neck Fractures / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D005272:Femur Neck / Q000000981:diagnostic imaging / Q000473:pathology; D005598:Fractures, Spontaneous / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D011877:Radionuclide Imaging; D006435:Renal Dialysis / Q000009:adverse effects*; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D001613:beta 2-Microglobulin / Q000032:analysis
D001613:beta 2-Microglobulin