Ribonucleoprotein particles with LINE-1 RNA in mouse embryonal carcinoma cells.
The LINE-1 repeat family is interspersed throughout mammalian genomes and is thought to be the result of duplicative transposition of LINE-1 sequences via an RNA intermediate. This report describes a ribonucleoprotein particle with LINE-1 RNA in the mouse embryonal carcinoma cell line F9. This ribonucleoprotein particle is a potential intermediate in the transposition of LINE-1 in the mouse genome.
Martin
S L
SL
Department of Cellular and Structural Biology, University of Colorado Health Sciences Center, Denver 80262.
D000818:Animals; D015152:Blotting, Northern; D002499:Centrifugation, Density Gradient; D004247:DNA; D054278:Embryonal Carcinoma Stem Cells; D051379:Mice; D014411:Neoplastic Stem Cells; D012313:RNA / Q000378:metabolism; D011995:Recombination, Genetic; D012091:Repetitive Sequences, Nucleic Acid; D012261:Ribonucleoproteins / Q000235:genetics* / Q000378:metabolism
D012261:Ribonucleoproteins; D012313:RNA; D004247:DNA