title: [Prostatic cancer before the age of 50--report of 7 cases].
abstract: Based on a retrospective series of 7 cases, the authors study the particular features of prostatic cancer before the age of 50 years. These 7 patients all had an advanced tumour with, in 4 cases, documented metastases. A single patient had a well differentiated tumour, while the others had a moderately or poorly differentiated or undifferentiated tumour. All patients died rapidly, except one who is currently receiving treatment with an LHRH agonist, with a follow-up of 25 months. On the basis of this study, the authors distinguish between prostatic cancers clinically detectable before the age of 50 years, and those which remain occult, leading to a histological discussion between a benign disease and true early cancer. In the light of these findings, systematic screening for prostatic cancer before the age of 50 years does not appear to be justified.
authors.affiliation: Service d'Urologie, CHU de Poitiers, France.
authors.forename: J
authors.initials: J
authors.lastname: Aubert
authors.forename: B
authors.initials: B
authors.lastname: Dore
authors.forename: J
authors.initials: J
authors.lastname: Irani
authors.forename: M N
authors.initials: MN
authors.lastname: Aubert
mesh_terms: D000367:Age Factors; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001706:Biopsy; D017373:Cyproterone Acetate / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D017430:Prostate-Specific Antigen / Q000097:blood; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome; D014567:Urography
chemical_list: D000970:Antineoplastic Agents; D017373:Cyproterone Acetate; D017430:Prostate-Specific Antigen
vernacular_title: Cancer prostatique avant 50 ans--a propos de 7 cas.