[Hyper- or isovolemic hemodilution in patients with stage II peripheral arterial occlusive disease].
The influence of hyper- and isovolaemic hemodilution using HES 200/0.5 6% (HES steril, Fresenius AG) on pain-free walking distance in patients with peripheral arterial occlusive disease stage II according to Fontaine was tested in a randomised investigation involving three groups. The increase in pain-free walking distance was significant both in the hypervolaemic and isovolaemic hemodilution group. The increase in both dilution groups did not differ but compared to a control group (infusion of Ringer lactate) it was significantly higher. Considerable changes concerning rheological parameters (decrease in haematocrit and plasma viscosity) were observed after isovolaemic hemodilution.
Kiesewetter
H
H
Abteilung für Klinische Hämostaseologie und Transfusionsmedizin, Universität des Saarlandes, Homburg Saar, BRD.
Jung
F
F
Blume
J
J
Spitzer
S
S
Birk
A
A
D000293:Adolescent; D000328:Adult; D000368:Aged; D001157:Arterial Occlusive Diseases / Q000097:blood / Q000628:therapy*; D001809:Blood Viscosity / Q000187:drug effects / Q000502:physiology; D001810:Blood Volume / Q000187:drug effects* / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D004903:Erythrocyte Aggregation / Q000187:drug effects / Q000502:physiology; D005080:Exercise Test; D005260:Female; D006400:Hematocrit; D006438:Hemodilution / Q000379:methods*; D006801:Humans; D006895:Hydroxyethyl Starch Derivatives / Q000008:administration & dosage*; D007383:Intermittent Claudication / Q000097:blood / Q000628:therapy; D007511:Ischemia / Q000097:blood / Q000628:therapy*; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged
D006895:Hydroxyethyl Starch Derivatives
Hyper- oder isovolämische Hämodilution bei Patienten mit peripherer arterieller Verschlusskrankheit im Stadium II.