title: Neuropeptides in atrial subepicardial ganglia of rats.
abstract: The distribution of several neuropeptides in subepicardial atrial ganglia was examined in the rat heart by using immunohistochemical techniques. Some of the ganglion cells in the right atrium exhibited neuropeptide Y-immunoreactivity while no immunostaining was found with antisera against atrial natriuretic polypeptide (ANF), substance P, vasoactive intestinal polypeptide (VIP), and calcitonin gene-related peptide (CGRP). Nerve fibers in and around the ganglia showed neuropeptide Y, calcitonin gene-related peptide and vasoactive intestinal polypeptide immunoreactivities. Some of these immunoreactive fibers (substance P, calcitonin gene-related peptide, neuropeptide Y) formed relatively dense networks around blood vessels and capillaries. Atrial natriuretic polypeptide-like immunoreactivity which was present in atrial myocytes failed to show up in any neuronal elements in the rat heart.
authors.affiliation: Institute of Biochemistry, Armenian Acad. Sci., Yerevan.
authors.forename: S
authors.initials: S
authors.lastname: Abrahamian
authors.forename: M
authors.initials: M
authors.lastname: Fodor
authors.forename: T
authors.initials: T
authors.lastname: Görcs
authors.forename: A
authors.initials: A
authors.lastname: Galoyan
authors.forename: M
authors.initials: M
authors.lastname: Palkovits
mesh_terms: D000818:Animals; D009320:Atrial Natriuretic Factor / Q000032:analysis; D015740:Calcitonin Gene-Related Peptide / Q000032:analysis; D005260:Female; D005724:Ganglia / Q000737:chemistry* / Q000166:cytology; D006321:Heart / Q000294:innervation*; D006325:Heart Atria; D008297:Male; D009412:Nerve Fibers / Q000737:chemistry; D009478:Neuropeptide Y / Q000032:analysis; D009479:Neuropeptides / Q000032:analysis*; D051381:Rats; D013373:Substance P / Q000032:analysis; D014660:Vasoactive Intestinal Peptide / Q000032:analysis
chemical_list: D009478:Neuropeptide Y; D009479:Neuropeptides; D013373:Substance P; D014660:Vasoactive Intestinal Peptide; D009320:Atrial Natriuretic Factor; D015740:Calcitonin Gene-Related Peptide