title: Low dose epirubicin for hypercalcemia associated with renal pelvis carcinoma.
abstract: We present a case of hypercalcemia associated with a renal pelvis squamous neoplasm. Severe hyperleukocytosis was also present, resembling a leukaemoid reaction. After failure of standard therapy, we performed a trial of low dose epirubicin in this patient, obtaining a short-term clinical remission. Although a palliative non-toxic effect seems to be achievable with this approach, further studies are needed to ascertain the role of chemotherapy in the long-term control of this condition.
authors.affiliation: Department of Urology, Hospital Virgen del Camino, Pamplona, Spain.
authors.forename: J M
authors.initials: JM
authors.lastname: Castillo
authors.forename: J J
authors.initials: JJ
authors.lastname: Illarramendi
authors.forename: A
authors.initials: A
authors.lastname: Santiago
authors.forename: J L
authors.initials: JL
authors.lastname: Sebastián
mesh_terms: D000368:Aged; D002116:Calcitonin / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000150:complications*; D002295:Carcinoma, Transitional Cell / Q000150:complications*; D015251:Epirubicin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000188:drug therapy* / Q000209:etiology; D007680:Kidney Neoplasms / Q000150:complications*; D007955:Leukemoid Reaction / Q000209:etiology; D009378:Neoplasms, Multiple Primary / Q000150:complications*; D010166:Palliative Care
chemical_list: D015251:Epirubicin; D002116:Calcitonin