FK 506 mechanism of nephrotoxicity: stimulatory effect on endothelin secretion by cultured kidney cells and tubular cell toxicity in vitro.
Moutabarrik
A
A
Department of Urology, Osaka University Hospital, Japan.
Ishibashi
M
M
Fukunaga
M
M
Kameoka
H
H
Takano
Y
Y
Kokado
Y
Y
Takahara
S
S
Jiang
H
H
Sonoda
T
T
Okuyama
A
A
D000118:Acetylglucosaminidase / Q000378:metabolism; D000818:Animals; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D016572:Cyclosporine / Q000494:pharmacology; D016232:Endothelins / Q000378:metabolism*; D005920:Glomerular Mesangium / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D007684:Kidney Tubules / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008297:Male; D051381:Rats; D011917:Rats, Inbred Lew; D016559:Tacrolimus / Q000494:pharmacology* / Q000633:toxicity
D016232:Endothelins; D016572:Cyclosporine; D007770:L-Lactate Dehydrogenase; D000118:Acetylglucosaminidase; D016559:Tacrolimus