Exchange of copper between serum albumin and bleomycin.
1. The present in vitro study shows that bleomycin is able to take up copper from albumin, which functions as a copper transport protein in plasma. 2. Calculations, based on plasma concentrations of Cu(II)-albumin and bleomycin, suggest that only a small fraction of bleomycin (less than 3%) may directly accept copper from Cu(II)-albumin.
Løvstad
R A
RA
Institute of Medical Biochemistry, University of Oslo, Norway.
D001761:Bleomycin / Q000737:chemistry*; D002850:Chromatography, Gel; D003300:Copper / Q000737:chemistry*; D012709:Serum Albumin / Q000737:chemistry*; D013057:Spectrum Analysis
D012709:Serum Albumin; D001761:Bleomycin; D003300:Copper