title: Enhanced resistance against Listeria monocytogenes achieved by pretreatment with granulocyte colony-stimulating factor.
abstract: Phagocytosis, H2O2 production, Mac-1 expression, and in vivo elimination of Listeria monocytogenes were enhanced in granulocyte colony-stimulating factor (G-CSF)-treated mice. Transfer of polymorphonuclear leukocytes prolonged survival of mice infected with a lethal dose of L. monocytogenes. G-CSF augments the functions of polymorphonuclear leukocytes and thus plays a role in protection.
authors.affiliation: Department of Microbiology, National Defense Medical College, Saitama, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Shinomiya
authors.forename: S
authors.initials: S
authors.lastname: Tsuru
authors.forename: Y
authors.initials: Y
authors.lastname: Katsura
authors.forename: S
authors.initials: S
authors.lastname: Kayashima
authors.forename: K
authors.initials: K
authors.lastname: Nomoto
mesh_terms: D000818:Animals; D005260:Female; D016179:Granulocyte Colony-Stimulating Factor / Q000494:pharmacology*; D008088:Listeriosis / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D009504:Neutrophils / Q000187:drug effects / Q000276:immunology; D011994:Recombinant Proteins / Q000494:pharmacology
chemical_list: D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor