Histological analysis of ultrasonic images of the prostate: an accurate technique.
Ultrasonography of the prostate furnishes images which still cannot be fully interpreted morphologically. In a cadaver study, the ultrasound images of two groups (21 and 19) prostates, obtained in a water bath, were compared with histology slides taken at corresponding levels. In the first part of the study, using a 4 MHz probe, there was a correlation between hyperechoic lesions and stone formations in 9 out of 15 cases. A relation between hypoechoic lesions and the existence of a carcinoma could also be established in 4 out of 12 cases. In the second part of the study, using a 7 MHz probe, there was a correlation between hyperechoic lesions and stone formations in all cases. Hypoechoic lesions correlated with the presence of a carcinoma in 1 out of 8 cases. The technique used appears to be well suited for the comparative study of ultrasound images and histology. Application of the 7 MHz probe is preferable as, because of a better resolution, smaller lesions can be detected. The results of this study are not very encouraging for the use of transrectal ultrasound for the detection of small prostatic carcinomas.
Hendrikx
A J
AJ
Department of Urology, St. Radboud University Hospital, Nijmegen, The Netherlands.
de la Rosette
J J
JJ
van Helvoort-van Dommelen
C A
CA
van Dijk
M A
MA
Semmelink
H
H
Rijntjes
N V
NV
Debruyne
F M
FM
D000368:Aged; D002102:Cadaver; D006801:Humans; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000000981:diagnostic imaging* / Q000473:pathology; D011470:Prostatic Hyperplasia / Q000000981:diagnostic imaging*; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging*; D014463:Ultrasonography / Q000379:methods