title: Centrally acting anorectic drugs: a clinical perspective.
abstract: This paper reviews the anorectic activity and effectiveness of catecholamine and serotoninergic anorectic drugs in the management of obesity. It discusses the clinical implications of the experimental findings and suggests prescribing strategies for effective long-term therapeutic benefit. The authors advocate that there is a role for the recently developed serotonin-mediated anorectic compounds in the treatment of obesity, particularly in those individuals with abnormal glucose tolerance or who are hypertensive.
authors.affiliation: Academic Unit of Human Psychopharmacology, Medical College of St Bartholomew's Hospital, London, UK.
authors.forename: T
authors.initials: T
authors.lastname: Silverstone
authors.forename: E
authors.initials: E
authors.lastname: Goodall
mesh_terms: D001067:Appetite Depressants / Q000494:pharmacology / Q000627:therapeutic use*; D002491:Central Nervous System Agents / Q000627:therapeutic use*; D004435:Eating / Q000187:drug effects; D006801:Humans; D006815:Hunger / Q000187:drug effects; D009765:Obesity / Q000188:drug therapy*
chemical_list: D001067:Appetite Depressants; D002491:Central Nervous System Agents