[Clinical significance of serum ferritin and acute phase reactant proteins levels in patients with cervical cancer].
Serum ferritin (SF) levels from 162 patients with cervical cancer and their serum alpha 1-acid glycoprotein (alpha 1-AGP). alpha 1-antitrypsin (alpha 1-AT. Transferrin (Tf) in most patients were determined. The result showed that concentration of SF, alpha 1-AGP, alpha 1-AT were significantly higher, while TF significantly lower in cervical carcinoma patients during active period than from patients with benign tumors and normal persons. The levels of SF. alpha 1-AGP. alpha 1-AT and Tf were significantly increased during the remission period. The positive rate of SF, alpha 1-AGP and Tf in cervical cancer patients during active period was significantly higher than that of alpha 1-AT. Serial determinations of SF, alpha 1-AGP and. Tf may be helpful in the monitoring of disease development and early detection of recurrence and metastases.
Xie
J F
JF
Tongji Hospital, Tong Ji Medical University, Wuhan.
D000209:Acute-Phase Proteins / Q000378:metabolism*; D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood*; D005260:Female; D005293:Ferritins / Q000097:blood*; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000097:blood; D009961:Orosomucoid / Q000378:metabolism; D014168:Transferrin / Q000378:metabolism; D002583:Uterine Cervical Neoplasms / Q000097:blood*; D000515:alpha 1-Antitrypsin / Q000378:metabolism
D000209:Acute-Phase Proteins; D014408:Biomarkers, Tumor; D009961:Orosomucoid; D014168:Transferrin; D000515:alpha 1-Antitrypsin; D005293:Ferritins