Visual scotomata resulting from lupus anticoagulant in a patient with lymphoma in remission.
Episodic cerebro or retinovascular ischemic events without apparent cause occur in patients with cancer. We report a patient in remission from lymphoma whose multiple episodes of presumed ocular ischemia occurred in the setting of a circulating lupus anticoagulant. Symptoms resolved following therapy with Warfarin.
Gruber
M L
ML
Massachusetts General Hospital, Boston.
Hochberg
F H
FH
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage; D001921:Brain / Q000473:pathology; D003520:Cyclophosphamide / Q000008:administration & dosage; D003907:Dexamethasone / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D006973:Hypertension / Q000150:complications; D002546:Ischemic Attack, Transient / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D016682:Lupus Coagulation Inhibitor / Q000032:analysis / Q000502:physiology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012074:Remission Induction; D012607:Scotoma / Q000188:drug therapy / Q000209:etiology*; D014750:Vincristine / Q000008:administration & dosage; D015349:Vision, Monocular; D014859:Warfarin / Q000627:therapeutic use
D016682:Lupus Coagulation Inhibitor; D001761:Bleomycin; D014750:Vincristine; D014859:Warfarin; D003907:Dexamethasone; D004317:Doxorubicin; D003520:Cyclophosphamide