title: [Contribution of a 3% solution of boric acid in the treatment of deep wounds with loss of substance].
abstract: The correct application of antiseptics to major surgical wounds must comply with appropriate protocols. Compliance with the protocol established by the CHRU of Nancy was evaluated by means of a questionnaire assessing the understanding of the protocol by the nursing staff and by a survey in the wards in which it was applied. The defects observed cannot be explained by a lack of efficacy for superficial wounds and deep wounds, as a randomised study of 42 wounds demonstrated the superiority of the protocol in relation to the use of another product which is widely used in the wards. In contrast, for deep wounds with loss of substance, the proposed protocol does not always achieve therapeutic success. This finding has led the authors to propose the use of a 3% boric acid solution based on a case-control study which demonstrated a significantly superior efficacy. All of the epidemiological and clinical elements are summarised in order to demonstrate the solid basis for compliance with antiseptic protocols of surgical wounds which can only be beneficial in terms of therapeutic success, length of hospital stay and cost savings.
authors.affiliation: Service de Chirurgie E, Centre Hospitalier Régional et Universitaire de Nancy.
authors.forename: J
authors.initials: J
authors.lastname: Borrelly
authors.forename: M F
authors.initials: MF
authors.lastname: Blech
authors.forename: G
authors.initials: G
authors.lastname: Grosdidier
authors.forename: C
authors.initials: C
authors.lastname: Martin-Thomas
authors.forename: P
authors.initials: P
authors.lastname: Hartemann
mesh_terms: D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D001888:Boric Acids / Q000008:administration & dosage / Q000627:therapeutic use*; D002710:Chlorhexidine / Q000627:therapeutic use; D002985:Clinical Protocols; D005069:Evaluation Studies as Topic; D005602:France; D006801:Humans; D006863:Hydrogen-Ion Concentration; D009779:Occlusive Dressings; D011206:Povidone-Iodine / Q000627:therapeutic use; D013530:Surgical Wound Infection / Q000188:drug therapy* / Q000517:prevention & control; D011795:Surveys and Questionnaires
chemical_list: D000891:Anti-Infective Agents, Local; D001888:Boric Acids; D011206:Povidone-Iodine; D002710:Chlorhexidine; C032688:boric acid
vernacular_title: Apport d'une solution d'acide borique à 3% pour le traitement des plaies profondes avec perte de substance.