[Deep white matter hyperintensity in the occipital lobe on T2-weighted MRI in children. II. Classification based on the signal intensity].
Twenty-seven children, who had deep white matter hyperintensity in the occipital lobe (DWMH) on T2-weighted MRI, were classified into two groups, mild and severe, based on the signal intensity. The frequency of mild DWMH, which was iso-or hyperintense relative to the gray matter but hypointense relative to cerebrospinal fluid (CSF), decreased with aging; mild DWMH might result from a delayed myelination in the central nervous system. However, the frequency of severe DWMH, which was iso-or hyperintense relative to CSF, was not related to aging and was significantly high in severely retarded children. Therefore, severe DWMH might be a new indicator of mental retardation in children.
Miyazaki
M
M
Department of Pediatrics, School of Medicine, University of Tokushima.
Hashimoto
T
T
D000293:Adolescent; D000375:Aging / Q000473:pathology; D001921:Brain / Q000473:pathology*; D001932:Brain Neoplasms / Q000175:diagnosis; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000175:diagnosis; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male; D008527:Medulloblastoma / Q000175:diagnosis; D009778:Occipital Lobe / Q000473:pathology*