title: In vivo neutron activation analysis of organ cadmium burdens. Referent levels in liver and kidney and the impact of smoking.
abstract: In vivo neutron activation measurements of liver and kidney cadmium have been made in 77 exposed workers and 101 referents. Cadmium levels were higher in exposed workers than in referents; both in liver, 25.7 cf. 0.6 micrograms/g, and kidney, 17.9 cf. 2.7 mg. The 19 referents who never smoked had lower mean organ cadmium burdens than the other referents, the difference achieving statistical significance in the kidney, p less than .01. Cigarette smoking was estimated to increase cadmium body burden by 370 +/- 140 micrograms/pack year. These referent cadmium levels are similar to, although slightly below, previous in vivo and autopsy data.
authors.affiliation: School of Physics and Space Research, University of Birmingham, England.
authors.forename: D M
authors.initials: DM
authors.lastname: Franklin
authors.forename: C J
authors.initials: CJ
authors.lastname: Guthrie
authors.forename: D R
authors.initials: DR
authors.lastname: Chettle
authors.forename: M C
authors.initials: MC
authors.lastname: Scott
authors.forename: H J
authors.initials: HJ
authors.lastname: Mason
authors.forename: A G
authors.initials: AG
authors.lastname: Davison
authors.forename: A J
authors.initials: AJ
authors.lastname: Newman Taylor
mesh_terms: D001822:Body Burden; D002104:Cadmium / Q000032:analysis*; D006801:Humans; D007668:Kidney / Q000737:chemistry*; D008099:Liver / Q000737:chemistry*; D008297:Male; D008875:Middle Aged; D009501:Neutron Activation Analysis / Q000379:methods*; D016273:Occupational Exposure; D012907:Smoking / Q000009:adverse effects
chemical_list: D002104:Cadmium