[Use of contrykal in intensive care of myocardial infarct during the prehospital stage].
The effect of contrykal was evaluated in 146 male patients with first myocardial infarction and 116 control patients in the prehospital period. Intravenous contrykal was given in a single dose of 20,000 IU within 30 to 360 minutes of onset of myocardial infarction, followed by intravenous administration of heparin, 10,000-15,000 U. The control patients received conventional therapy. Earlier application of contrykal contributed to attenuation of clinical manifestations of myocardial infarction. The drug was found to produce a clear-cut antianginal effect. It also exerted a positive action on the abdominal syndrome. There was a rapid inverse dynamics in ECG changes, fermentaemia (aspartate aminotransferase and alanine aminotransferase), decreased myocardial necrotic mass.
Leshchinskiĭ
L A
LA
Valeeva
R M
RM
Eĭkhman
L L
LL
D000328:Adult; D000368:Aged; D000410:Alanine Transaminase / Q000097:blood; D007611:Aprotinin / Q000008:administration & dosage / Q000627:therapeutic use*; D001219:Aspartate Aminotransferases / Q000097:blood; D004796:Clinical Enzyme Tests; D003422:Critical Care; D004562:Electrocardiography; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000188:drug therapy*
D007611:Aprotinin; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
Primenenie kontrykala v intensivnoĭ terapii infarkta miokarda na dogospital'nom étape.