Near-triploid myeloblastic transformation of chronic myeloid leukemia with bizarre blast morphology.
We describe a case of chronic myeloid leukemia (CML) in myeloblastic transformation in which near-triploidy with complex karyotypic abnormalities occurred together with unusual blast morphology. A review of the literature shows that near-triploidy is extremely unusual in blastic transformation (BT) of CML.
Kwong
Y L
YL
University Department of Pathology, Queen Mary Hospital, Pokfulam, Hong Kong.
Chan
A Y
AY
Chan
L C
LC
Wong
K F
KF
Chu
Y C
YC
D001752:Blast Crisis; D001853:Bone Marrow / Q000473:pathology; D002869:Chromosome Aberrations; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000235:genetics* / Q000473:pathology; D007962:Leukocytes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D014314:Trisomy