T-cell and B-cell function in lupus.
Investigation into the nature of the immunologic abnormalities responsible for autoantibody production continues to be an extremely active area of research in lupus. This paper reviews several areas of current research relevant to our understanding of T-cell and B-cell function in lupus.
Handwerger
B S
BS
University of Maryland School of Medicine, Baltimore.
D000818:Animals; D000917:Antibody Formation; D015703:Antigens, CD / Q000032:analysis; D001323:Autoantibodies / Q000276:immunology; D001327:Autoimmune Diseases / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology / Q000502:physiology*; D018956:CD5 Antigens; D002455:Cell Division; D006801:Humans; D007958:Leukocyte Count; D008180:Lupus Erythematosus, Systemic / Q000473:pathology / Q000503:physiopathology*; D010641:Phenotype; D011948:Receptors, Antigen, T-Cell / Q000502:physiology; D015398:Signal Transduction; D013601:T-Lymphocytes / Q000473:pathology / Q000502:physiology*; D006377:T-Lymphocytes, Helper-Inducer / Q000502:physiology; D013950:Thymus Gland / Q000503:physiopathology
D015703:Antigens, CD; D001323:Autoantibodies; D018956:CD5 Antigens; D011948:Receptors, Antigen, T-Cell