Retinoic acid receptor transcripts in human umbilical vein endothelial cells.
Human umbilical vein endothelial cells contain high levels of mRNA for the beta-retinoic acid receptor, and very low levels of alpha-retinoic acid receptor transcripts. The cells responded to retinoic acid with a significant induction of tissue transglutaminase expression but no alterations in the expression of beta-retinoic acid receptor transcripts. The physiological implications of the constitutive expression of this receptor in endothelial cells is discussed.
Fesus
L
L
Department of Biochemistry, University School of Medicine, Debrecen, Hungary.
Nagy
L
L
Basilion
J P
JP
Davies
P J
PJ
D015152:Blotting, Northern; D002352:Carrier Proteins / Q000235:genetics*; D002478:Cells, Cultured; D015342:DNA Probes; D004730:Endothelium, Vascular / Q000378:metabolism*; D015723:Gene Library; D006801:Humans; D015345:Oligonucleotide Probes; D011061:Poly A / Q000235:genetics; D012313:RNA / Q000235:genetics / Q000302:isolation & purification; D012333:RNA, Messenger; D018168:Receptors, Retinoic Acid; D015183:Restriction Mapping; D014158:Transcription, Genetic; D014212:Tretinoin / Q000378:metabolism*; D014471:Umbilical Veins
D002352:Carrier Proteins; D015342:DNA Probes; D015345:Oligonucleotide Probes; D012333:RNA, Messenger; D018168:Receptors, Retinoic Acid; D011061:Poly A; D014212:Tretinoin; D012313:RNA