Familial occurrence of thrombotic thrombocytopenic purpura in two sisters during pregnancy.
The etiology of thrombotic thrombocytopenic purpura is not fully understood. A genetic predisposition and other inciting factors have been suggested by several studies to bring about the full-blown syndrome. We report two cases of thrombotic thrombocytopenic purpura in two sisters with sudden onset during late pregnancy.
Wiznitzer
A
A
Division of Obstetrics and Gynecology, Soroka University Hospital, Beer-Sheva, Israel.
Mazor
M
M
Leiberman
J R
JR
Bar-Levie
Y
Y
Gurman
G
G
Glezerman
M
M
D000328:Adult; D005260:Female; D006801:Humans; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic; D011697:Purpura, Thrombotic Thrombocytopenic / Q000235:genetics* / Q000628:therapy