Zinc-positive boutons in the cerebral cortex of lizards show glutamate immunoreactivity.
Zinc-positive boutons, originating in the medial cortex of lizards, exhibit glutamate immunoreactivity. This finding supports the presumed homology between lizard zinc-positive boutons and the hippocampal mossy fibres of mammals, which are also glutamate-immunoreactive and zinc-positive. Zinc-positive boutons of lizards contain a chelatable pool of zinc located in the hippocampal mossy fibres of mammals. These synaptic systems also contain glutamate, which indicates a possible simultaneous action of zinc and glutamate during synaptic transmission.
Martinez-Guijarro
F J
FJ
Catedra de Citologia e Histologia, Facultad de Ciencias Biologicas, Universidad de Valencia, Burjasot, Spain.
Soriano
E
E
Del Rio
J A
JA
Lopez-Garcia
C
C
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D002540:Cerebral Cortex / Q000737:chemistry / Q000648:ultrastructure*; D005971:Glutamates / Q000032:analysis* / Q000276:immunology; D006624:Hippocampus / Q000737:chemistry / Q000648:ultrastructure; D008116:Lizards / Q000033:anatomy & histology*; D013194:Staining and Labeling / Q000379:methods*; D013569:Synapses / Q000737:chemistry / Q000648:ultrastructure*; D013572:Synaptic Vesicles / Q000737:chemistry / Q000648:ultrastructure; D015032:Zinc / Q000378:metabolism
D000911:Antibodies, Monoclonal; D005971:Glutamates; D015032:Zinc