title: [Serologic study of patients with leptospirosis using TR antigen].
abstract: This paper deals with 254 monosera of patients with leptospirosis verified by macroagglutination test with thermoresistant antigen (TR antigen) and passive hemaglutination (HA), as reference technique. The TR antigen was elaborated according to the method described by Mailloux and coworkers, 1974, with modifications, and it showed a wide generic reactivity. It was specific when serologic test were performed with hyperimmune sera obtained from febrile disease producing bacteria and the causal agent of syphilis. The results obtained by both serologic tests were compared and it was observed that 106 sera (41.73%) were reactive to HA, which showed a highly significant statistical difference between the two techniques; so a lower sensibility of TR macroagglutination test was determined.
authors.affiliation: Instituto de Medicina Tropical Pedro Kouri, Laboratorio Nacional de Referencia de Leptospiras.
authors.forename: J D
authors.initials: JD
authors.lastname: Regalado Segui
authors.forename: C
authors.initials: C
authors.lastname: López Acosta
authors.forename: P
authors.initials: P
authors.lastname: Pedroso Peña
authors.forename: L R
authors.initials: LR
authors.lastname: Ramos Pérez
mesh_terms: D000942:Antigens, Bacterial / Q000276:immunology*; D000939:Epitopes / Q000276:immunology*; D006801:Humans; D007919:Leptospira / Q000276:immunology*; D007922:Leptospirosis / Q000175:diagnosis*; D012680:Sensitivity and Specificity
chemical_list: D000942:Antigens, Bacterial; D000939:Epitopes
vernacular_title: Estudio serológico de pacientes con leptospirosis mediante el antígeno TR.