title: Genetic polymorphism of human glutamate oxaloacetate transaminase (GOT1) detected using isoelectric focusing and a sensitive and positive staining method.
abstract: Genetic polymorphism of glutamate oxaloacetate transaminase (GOT1) was demonstrated in human erythrocytes by isoelectric focusing in thin layer polyacrylamide gels and a sensitive and positive detection method. Using this technique, five phenotypes, GOT1 1, 2, 2-1, 3-1 and 3-2 were determined and the estimated gene frequencies of GOT1*1, GOT1*2 and GOT1*3 in the Japanese population were 0.9740, 0.0173 and 0.0087, respectively.
authors.affiliation: Department of Internal Medicine and Medical Genetics, Fukui Medical School, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Nakanaga
authors.forename: D
authors.initials: D
authors.lastname: Nadano
authors.forename: T
authors.initials: T
authors.lastname: Yasuda
authors.forename: E
authors.initials: E
authors.lastname: Tenjo
authors.forename: K
authors.initials: K
authors.lastname: Sawazaki
authors.forename: R
authors.initials: R
authors.lastname: Iida
authors.forename: N
authors.initials: N
authors.lastname: Fujiki
authors.forename: K
authors.initials: K
authors.lastname: Kishi
mesh_terms: D001219:Aspartate Aminotransferases / Q000235:genetics*; D004912:Erythrocytes / Q000201:enzymology*; D005787:Gene Frequency; D006801:Humans; D007525:Isoelectric Focusing; D007564:Japan; D010641:Phenotype; D011110:Polymorphism, Genetic / Q000235:genetics*; D012016:Reference Values; D013194:Staining and Labeling
chemical_list: D001219:Aspartate Aminotransferases