Glomerular filtration rate in healthy Nigerian children and in children with sickle cell anaemia in a steady state.
In a prospective study, the glomerular filtration rate (GFR) of 365 Nigerian children aged 4-14 years was determined at the University of Nigeria Teaching Hospital, Enugu. The subjects were made up of 305 healthy children and 60 children with sickle cell anaemia in a steady state. For the healthy children who served as controls, the mean (SD) GFR was 112 (35)ml/min/1.73m2, there being no sex difference. The peak GFR was recorded in boys at 9 years and girls at 13 years. In the children with sickle cell anaemia in a steady state, the mean (SD) GFR was 111 (36), a figure similar to that of normal controls.
Okoro
B A
BA
Department of Paediatrics, University of Nigeria Teaching Hospital, Enugu.
Onwuameze
I C
IC
D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005919:Glomerular Filtration Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D009549:Nigeria; D011446:Prospective Studies; D012016:Reference Values