Selenium in Kashin-Beck disease areas.
In this article, the duplication portion technique was used to determine the daily intakes of selenium and ten other elements in the 24-h total diets collected in the typical Kashin-Beck endemic areas, i.e., Shanxi Province and Inner Mongolia Autonomous of China. The contents of Ca, Mg, Cu, Fe, Zn, Mn, Al, Sr, Ba, and P in freeze-dried samples were determined by ICP-AES. Se was determined by differential pulse catalytic polarography. The average Se contents in total diets of Shanxi Kashin-Beck endemic and nonendemic areas were 0.009 and 0.021 micrograms/g (dry weight), respectively (P less than 0.001), corresponding to the daily intakes for Se of 4.6 and 10.5 micrograms. After the Se-supplemented fertilizer was applied (225 g of Na2SeO3/ha), the average Se content in total diets of Kashin-Beck disease area was increased to 0.0336 micrograms/g, which corresponded to the average daily intake for Se of 16.8 micrograms. In Inner Mongolia Kashin-Beck endemic and nonendemic areas, the average Se contents in total diets were 0.006 and 0.017 micrograms/g, respectively (p less than 0.001), corresponding to the average daily intakes for Se of 3 and 8.5 micrograms. The contents of other ten elements in total diets in endemic and nonendemic areas were reported and compared.
Xu
L Q
LQ
Shanghai Institute of Metallurgy, Academia Sinica, Shanghai, China.
Sen
W X
WX
Xiong
Q H
QH
Huang
H M
HM
Schramel
P
P
D002681:China / Q000453:epidemiology; D004032:Diet; D005308:Fertilizers / Q000032:analysis; D005504:Food Analysis / Q000379:methods; D006801:Humans; D007592:Joint Diseases / Q000453:epidemiology* / Q000209:etiology / Q000378:metabolism; D012643:Selenium / Q000032:analysis* / Q000172:deficiency; D014131:Trace Elements / Q000032:analysis
D005308:Fertilizers; D014131:Trace Elements; D012643:Selenium