Genetic polymorphism of human glutamate oxaloacetate transaminase (GOT1) detected using isoelectric focusing and a sensitive and positive staining method.
Genetic polymorphism of glutamate oxaloacetate transaminase (GOT1) was demonstrated in human erythrocytes by isoelectric focusing in thin layer polyacrylamide gels and a sensitive and positive detection method. Using this technique, five phenotypes, GOT1 1, 2, 2-1, 3-1 and 3-2 were determined and the estimated gene frequencies of GOT1*1, GOT1*2 and GOT1*3 in the Japanese population were 0.9740, 0.0173 and 0.0087, respectively.
Nakanaga
M
M
Department of Internal Medicine and Medical Genetics, Fukui Medical School, Japan.
Nadano
D
D
Yasuda
T
T
Tenjo
E
E
Sawazaki
K
K
Iida
R
R
Fujiki
N
N
Kishi
K
K
D001219:Aspartate Aminotransferases / Q000235:genetics*; D004912:Erythrocytes / Q000201:enzymology*; D005787:Gene Frequency; D006801:Humans; D007525:Isoelectric Focusing; D007564:Japan; D010641:Phenotype; D011110:Polymorphism, Genetic / Q000235:genetics*; D012016:Reference Values; D013194:Staining and Labeling
D001219:Aspartate Aminotransferases