Effect of turpentine on alpha 1-major acute phase concentration in normal and adrenalectomized rats.
Acute phase response of plasma alpha 1-major acute phase (alpha 1-MAP) was studied in normal and adrenalectomized rats. alpha 1-MAP basal levels were higher in female than in male rats. This protein, measured by radial immunodiffusion, increased significantly both in male and female rats 24 and 48 h after a turpentine stimulus, proving to be a positive acute phase protein for both sexes. In adrenalectomized male rats the increase of plasma alpha 1-MAP concentration was not different from that observed in sham-operated rats, suggesting that the acute phase response of this protein is not corticoid dependent.
Silveira
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VL
Departamento de Fisiologia, Escola Paulista de Medicina, São Paulo, Brasil.
Limãos
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EA
D000209:Acute-Phase Proteins / Q000032:analysis*; D000315:Adrenalectomy; D000818:Animals; D003345:Corticosterone / Q000097:blood*; D005260:Female; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D014425:Turpentine / Q000494:pharmacology*
D000209:Acute-Phase Proteins; D003345:Corticosterone; D014425:Turpentine