Cytokeratin expression in human cell lines derived from liver tumors.
Immunohistochemical staining of cell lines derived from human liver tumours showed that five cell lines derived from hepatocellular carcinoma (HCC) and hepatoblastoma were stained positively with monoclonal keratin antibodies, CK-5 (Ker-18-specific) and KL-1 (broad specificity), but not with CK-7 (Ker-7-specific). On the other hand, four carcinoma cell lines derived from the biliary system were stained positively with not only CK-5 and KL-1, but also CK-7.
Tokiwa
T
T
Department of Pathology, Okayama University School of Medicine, Japan.
Endo
A
A
Namba
M
M
D000418:Albumins / Q000032:analysis; D000469:Alkaline Phosphatase / Q000032:analysis; D000911:Antibodies, Monoclonal / Q000276:immunology; D001650:Bile Duct Neoplasms / Q000473:pathology; D014408:Biomarkers, Tumor / Q000032:analysis; D002277:Carcinoma / Q000473:pathology; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D005706:Gallbladder Neoplasms / Q000473:pathology; D006801:Humans; D007633:Keratins / Q000032:analysis*; D008113:Liver Neoplasms / Q000473:pathology*; D009363:Neoplasm Proteins / Q000032:analysis*; D014407:Tumor Cells, Cultured / Q000378:metabolism; D000509:alpha-Fetoproteins / Q000032:analysis
D000418:Albumins; D000911:Antibodies, Monoclonal; D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins; D000509:alpha-Fetoproteins; D007633:Keratins; D000469:Alkaline Phosphatase