title: [Clinical study of urinary fungal infection: survey of patient background and fungal strains from the urine].
abstract: Clinical features of urinary fungal infections were analyzed in 152 patients in whom fungi were cultured from urine and mycologically identified between February, 1989 and June, 1990. The average age was 66 years old, and approximately 70% of the patients were 60 years old or older. Systemic and urinary tract underlying diseases were observed in 145 patients (95.4%) and 70 patients (46.1%) had urinary indwelling catheters. Previous use of antimicrobial agents before isolation of urinary fungi was recorded in 103 patients (67.8%), the 2nd and 3rd generation cephems and new quinolones being most frequent. A mixture of fungi and bacteria was observed in 68 patients (44.7%). Gram-positive cocci were isolated from 50% of them. Of 173 strains of fungi, C. glabrata was the most frequent (31.2%), followed by C. albicans (27.8%), C. tropicalis (17.3%) and T. beigelii (15.0%). All strains of C. glabrata, C. albicans, C. tropicalis and T. beigelii were highly sensitive to flucytosine (5-FC), miconazole (MCZ) and amphotericin B (AMPH), except for 3 strains which were resistant to 5-FC. The consecutiveness was confirmed by repeated culture in 59.4% of the patients. Fungi in the urine, however, spontaneously disappeared in the other patients.
authors.affiliation: Department of Urology, Gifu University School of Medicine.
authors.forename: S
authors.initials: S
authors.lastname: Fujihiro
authors.forename: H
authors.initials: H
authors.lastname: Ehara
authors.forename: K
authors.initials: K
authors.lastname: Tokuyama
authors.forename: S
authors.initials: S
authors.lastname: Yamada
authors.forename: Y
authors.initials: Y
authors.lastname: Harada
authors.forename: M
authors.initials: M
authors.lastname: Kanematu
authors.forename: Y
authors.initials: Y
authors.lastname: Ban
authors.forename: Y
authors.initials: Y
authors.lastname: Kawada
mesh_terms: D000368:Aged; D002408:Catheters, Indwelling; D005260:Female; D005658:Fungi / Q000302:isolation & purification; D006095:Gram-Positive Cocci / Q000302:isolation & purification; D006801:Humans; D008297:Male; D009181:Mycoses / Q000382:microbiology*; D011470:Prostatic Hyperplasia / Q000150:complications; D014525:Urethral Stricture / Q000150:complications; D001750:Urinary Bladder, Neurogenic / Q000150:complications; D014552:Urinary Tract Infections / Q000382:microbiology*; D014556:Urine / Q000382:microbiology; D014570:Urologic Diseases / Q000150:complications*