Identification of germ tube cell wall antigens of Candida albicans.
The reactivity of affinity-purified antibody to two components of germ tube cell wall extracts of Candida albicans showed that the components shared a common determinant(s). Surface expression of at least one of these determinants was demonstrated by indirect immunofluorescence where antibody binding was observed only on the hyphal extension of the organism.
Casanova
M
M
Department of Microbiology, Texas Tech University Health Sciences Center, Lubbock 79430.
Martìnez
J P
JP
Chaffin
W L
WL
D000946:Antigens, Fungal / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis; D015153:Blotting, Western; D002176:Candida albicans / Q000276:immunology* / Q000648:ultrastructure; D002473:Cell Wall / Q000276:immunology; D004591:Electrophoresis, Polyacrylamide Gel; D000939:Epitopes / Q000032:analysis; D005455:Fluorescent Antibody Technique
D000946:Antigens, Fungal; D000954:Antigens, Surface; D000939:Epitopes