10Sa RNA, a small stable RNA of Escherichia coli, is functional.
The ssrA gene, coding for the metabolically stable 10Sa RNA, affects cell growth. A mutant in which the chromosomal 10Sa RNA gene is interrupted by a cat insert does not produce detectable levels of 10Sa RNA, and it grows more slowly than the parental strain.
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Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110.
Apirion
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D015152:Blotting, Northern; D015139:Blotting, Southern; D015500:Chloramphenicol O-Acetyltransferase / Q000235:genetics; D004269:DNA, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics* / Q000254:growth & development; D005810:Multigene Family / Q000235:genetics*; D009154:Mutation / Q000235:genetics; D012329:RNA, Bacterial / Q000235:genetics*; D013696:Temperature
D004269:DNA, Bacterial; D012329:RNA, Bacterial; D015500:Chloramphenicol O-Acetyltransferase