Saponins from leaves of Acanthopanax hypoleucus Makino.
From the leaves of Acanthopanax hypoleucus Makino (Araliaceae), five triterpenoidal saponins, having oleanolic acid and hederagenin as sapogenins, were isolated. On the basis of chemical and spectral data, the structures of two new saponins, named hypoleucosides A (1), and B (5) were elucidated as follows: 1; 3-O-beta-D-glucopyranosyl 11 alpha-methoxy-oleanolic acid 28-O-beta-D-glucopyranosyl ester, 5; 3-O-beta-D-glucopyranosyl-(1----2)-alpha-L-arabinopyranosyl-(1---- 4)-beta-D-glucopyranosyl oleanolic acid 28-O-beta-D-glucopyranosyl-(1----6)-beta-D-glucopyranosyl ester.
Kohda
H
H
Institute of Pharmaceutical Sciences, Hiroshima Univeristy School of Medicine, Japan.
Tanaka
S
S
Yamaoka
Y
Y
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000494:pharmacology; D009189:Avian Myeloblastosis Virus / Q000187:drug effects; D008975:Molluscacides; D010946:Plants, Medicinal / Q000032:analysis*; D018894:Reverse Transcriptase Inhibitors; D012503:Saponins / Q000302:isolation & purification* / Q000494:pharmacology / Q000633:toxicity; D012908:Snails
D000972:Antineoplastic Agents, Phytogenic; D008975:Molluscacides; D018894:Reverse Transcriptase Inhibitors; D012503:Saponins