title: Long-term effect of retrobulbar hematomas on the vision of cynomolgus monkeys.
abstract: Using the monkey model previously developed, we investigated the long-term effects of retrobulbar hematoma-induced retinal ischemia on functional vision and retinal histology. In this experimental model, ischemic periods of up to 120 minutes did not cause permanent visual deficits, as measured by flashed evoked visual potentials. Similarly, retinal histology showed no evidence of ischemic injury. From this we conclude that blindness after blepharoplasty is not due to retrobulbar hematomas alone and that additional predisposing factors are involved. The most likely additional factor is preexisting occult vascular ocular pathology.
authors.affiliation: Division of Plastic Surgery, Washington University School of Medicine, St. Louis, Mo.
authors.forename: V L
authors.initials: VL
authors.lastname: Young
authors.forename: C A
authors.initials: CA
authors.lastname: Gumucio
authors.forename: H
authors.initials: H
authors.lastname: Lund
authors.forename: R
authors.initials: R
authors.lastname: McMahon
authors.forename: K
authors.initials: K
authors.lastname: Ueda
authors.forename: L
authors.initials: L
authors.lastname: Pidgeon
mesh_terms: D000818:Animals; D005074:Evoked Potentials, Visual; D006406:Hematoma / Q000150:complications* / Q000503:physiopathology; D007511:Ischemia / Q000209:etiology* / Q000503:physiopathology; D008252:Macaca fascicularis; D009916:Orbital Diseases / Q000150:complications* / Q000503:physiopathology; D012160:Retina / Q000473:pathology / Q000503:physiopathology*; D012161:Retinal Artery; D013997:Time Factors; D014785:Vision, Ocular / Q000502:physiology*