title: Plasma cholesterol-lowering potential of edible-oil blends suitable for commercial use.
abstract: We tested semihardened blends of edible oils, suitable for commercial food manufacture, with a lower-than-conventional saturated fatty acid content, for their effects on plasma cholesterol. Twenty-six mildly hypercholesterolemic men took part in a double-blind crossover experiment in which two test blends were compared with two control dietary periods [which resembled the Australian fat intake: proportions of polyunsaturated, monounsaturated, and saturated fatty acids (PMS) 0.4:0.9:1]. PMS in the test diets was approximately 0.8:1.3:1 and resulted in significantly lower LDL-cholesterol concentrations (reductions of less than or equal to 7.7%). HDL cholesterol and plasma triglyceride were unchanged. The trans fatty acid (mainly elaidic) content of the blends was 16%, raising its contribution to energy by 4% but without apparent effect on LDL and HDL concentrations. Provided the overall ratio of linoleic acid to palmitic acid in commercial edible-oil blends exceeds that in the prevailing national diet, partial hydrogenation will not negate the LDL-lowering potential.
authors.affiliation: CSIRO Division of Human Nutrition, Adelaide, South Australia.
authors.forename: P J
authors.initials: PJ
authors.lastname: Nestel
authors.forename: M
authors.initials: M
authors.lastname: Noakes
authors.forename: G B
authors.initials: GB
authors.lastname: Belling
authors.forename: R
authors.initials: R
authors.lastname: McArthur
authors.forename: R M
authors.initials: RM
authors.lastname: Clifton
authors.forename: M
authors.initials: M
authors.lastname: Abbey
mesh_terms: D000328:Adult; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D004042:Dietary Fats, Unsaturated / Q000627:therapeutic use*; D004311:Double-Blind Method; D005227:Fatty Acids / Q000008:administration & dosage / Q000097:blood; D006801:Humans; D006937:Hypercholesterolemia / Q000178:diet therapy*; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D004042:Dietary Fats, Unsaturated; D005227:Fatty Acids; D014280:Triglycerides; D002784:Cholesterol