title: Primary vaginal tuberculosis after vaginal carcinoma.
abstract: A case of primary vaginal tuberculosis is reported. A 62-year-old woman presented with a slightly eroded, granular vaginal lesion 10 months after radiation therapy for Stage II vaginal squamous cell carcinoma. She had previously undergone a total abdominal hysterectomy and left salpingo-oophorectomy at age 37 for abnormal uterine bleeding. This presentation of genital tract tuberculosis is unusual because of the location of the primary lesion, the age at presentation, the occurrence after radiation therapy, and the possible means of infection. We emphasize the need to maintain a high index of suspicion and to biopsy any suspicious vaginal lesions.
authors.affiliation: Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas 75235-9032.
authors.forename: W H
authors.initials: WH
authors.lastname: Kutteh
authors.forename: K D
authors.initials: KD
authors.lastname: Hatch
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D014376:Tuberculosis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D014623:Vaginal Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D014625:Vaginal Neoplasms / Q000473:pathology / Q000532:radiotherapy*
chemical_list: D007538:Isoniazid