Further immunohistochemical study of Crooke's hyalin.
For analysis of the cytokeratin (CK) of Crooke's cells, 28 post-mortem pituitary glands with unequivocal Crooke's hyaline change were investigated immunohistochemically using monoclonal antibodies for CK subfamilies. Crooke's hyalin was positive for CK 8 [molecular weight 52.5 kilodalton (KD)] and 18 (45 KD) but negative for skin-, cornea- and esophageal-typed CKs.
Uei
Y
Y
Cytology Section, National Cancer Center Hospital, Japan.
Kanzaki
M
M
Yabana
T
T
D000911:Antibodies, Monoclonal; D001491:Basophils / Q000378:metabolism*; D006801:Humans; D006818:Hyalin / Q000378:metabolism*; D007150:Immunohistochemistry; D007633:Keratins / Q000737:chemistry / Q000378:metabolism; D008970:Molecular Weight; D010902:Pituitary Gland / Q000166:cytology / Q000378:metabolism*
D000911:Antibodies, Monoclonal; D007633:Keratins