Lung transplantation of ventilator-dependent patients. The Washington University Lung Transplantation Group.
During the last few years, lung transplantation has been extended to patients with a variety of end-stage lung diseases, but recipient selection guidelines have remained relatively strict. Ventilator-dependent patients have traditionally been considered poor candidates for transplantation. However, patients who have been thoroughly evaluated and accepted for transplantation and subsequently develop respiratory failure caused by progression and/or exacerbation of their underlying disease and recipients who experience respiratory failure caused by graft failure may be suitable candidates while ventilator-dependent if no other major complications or contraindications arise before a donor organ becomes available.
Low
D E
DE
Department of Surgery, Washington University School of Medicine, St. Louis 63110.
Trulock
E P
EP
Kaiser
L R
LR
Pasque
M K
MK
Ettinger
N A
NA
Dresler
C
C
Cooper
J D
JD
D000328:Adult; D006084:Graft Rejection; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008173:Lung Diseases, Obstructive / Q000601:surgery / Q000628:therapy; D016040:Lung Transplantation; D008297:Male; D008875:Middle Aged; D011656:Pulmonary Emphysema / Q000601:surgery / Q000628:therapy; D011658:Pulmonary Fibrosis / Q000601:surgery / Q000628:therapy; D011859:Radiography; D012121:Respiration, Artificial