Hb F-Cosenza or G gamma 25(B7)Gly----Glu: a new fast-moving fetal hemoglobin variant.
A fast-moving gamma chain variant was discovered in the cord blood of a newborn during a screening program carried out in the northern region of Calabria, Southern Italy. The structural analysis showed a Gly----Glu substitution at position 25 of the G gamma chain indicating a new fetal hemoglobin variant that was named Hb F-Cosenza.
Qualtieri
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Centro Studi delle Microcitemie Cosenza, Italy.
Crescibene
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Bagalà
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De Marco
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EV
Bria
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Brancati
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C
D000595:Amino Acid Sequence; D001797:Blood Protein Electrophoresis; D002851:Chromatography, High Pressure Liquid; D004588:Electrophoresis, Cellulose Acetate; D005312:Fetal Blood / Q000737:chemistry; D005319:Fetal Hemoglobin / Q000235:genetics / Q000302:isolation & purification*; D005914:Globins / Q000235:genetics*; D006455:Hemoglobins, Abnormal / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D007231:Infant, Newborn / Q000097:blood; D008297:Male; D008403:Mass Screening; D008969:Molecular Sequence Data; D010449:Peptide Mapping
D006455:Hemoglobins, Abnormal; C074594:hemoglobin F-Cosenza; D005914:Globins; D005319:Fetal Hemoglobin