title: Cell culture study of the vestibular ganglion cells. Morphology and immunohistochemical activity.
abstract: Incubation of vestibular ganglion cells from the rat fetus and chick embryos was successfully done demonstrating bipolar cells and two types of multipolar cells, small round cells and large cells, in the cell cultures produced. Vestibular ganglion cells were found to be highly irregular in size. Furthermore, the presence of neurotransmitters (choline acetyltransferase and substance P) was confirmed immunohistochemically. Substance P positive cells had many bipolar cells and some multipolar cells. However, choline acetyl transferase positive cells had some small multipolar cells but few bipolar cells. These findings suggest that all vestibular ganglion cells do not have the same function.
authors.affiliation: Department of Otolaryngology, Yamaguchi University School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Yamashita
authors.forename: T
authors.initials: T
authors.lastname: Sekitani
authors.forename: Y
authors.initials: Y
authors.lastname: Okinaka
authors.forename: T
authors.initials: T
authors.lastname: Inokuma
authors.forename: H
authors.initials: H
authors.lastname: Shimogori
authors.forename: K
authors.initials: K
authors.lastname: Moriya
authors.forename: H
authors.initials: H
authors.lastname: Hara
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D002642:Chick Embryo; D002795:Choline O-Acetyltransferase / Q000378:metabolism; D005260:Female; D005724:Ganglia / Q000166:cytology* / Q000378:metabolism / Q000502:physiology; D007150:Immunohistochemistry; D018377:Neurotransmitter Agents / Q000378:metabolism; D011247:Pregnancy; D051381:Rats; D013194:Staining and Labeling; D013373:Substance P / Q000378:metabolism; D014722:Vestibule, Labyrinth / Q000166:cytology* / Q000378:metabolism
chemical_list: D018377:Neurotransmitter Agents; D013373:Substance P; D002795:Choline O-Acetyltransferase