Eosinophilic hepatitis after ingestion of choline magnesium trisalicylate.
Choline magnesium trisalicylate is a non-acetylated salicylate used widely as a nonsteroidal anti-inflammatory drug. Although mild transient hepatotoxicity associated with aspirin and other salicylates has been well documented, most commonly with high-dose treatment for rheumatologic disorders 112), we report a case of severe hypersensitivity hepatitis with striking tissue and peripheral eosinophilia after ingestion of choline magnesium trisalicylate.
Nadkarni
M M
MM
Graduate Hospital, Philadelphia, Pennsylvania.
Peller
C A
CA
Retig
J
J
D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000150:complications / Q000209:etiology*; D002794:Choline / Q000009:adverse effects / Q000031:analogs & derivatives*; D004802:Eosinophilia / Q000139:chemically induced* / Q000150:complications; D005260:Female; D006801:Humans; D010003:Osteoarthritis / Q000188:drug therapy; D012459:Salicylates / Q000009:adverse effects*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D012459:Salicylates; C017959:choline magnesium trisalicylate; D002794:Choline