title: The discovery of FK-506 and U.S. development.
mesh_terms: D006084:Graft Rejection / Q000187:drug effects; D049673:History, 20th Century; D006801:Humans; D007564:Japan; D016377:Organ Transplantation; D010414:Pennsylvania; D016559:Tacrolimus / Q000266:history* / Q000494:pharmacology; D014481:United States
chemical_list: D016559:Tacrolimus