[The interferon status and circulating immunoglobulins during the interferon therapy of respiratory papillomatosis in children].
Studies on the functional activity of interferon (IF) system (interferon status and serum immunoglobulins levels) and its changes in the course of interferon therapy of juvenile respiratory papillomatosis are presented. The initial disorders in alpha-IF production and levels of circulating IF came to normal after interferon therapy. Correlative changes of the following parameters occurred: a decrease in the level of circulating IF and IgM and simultaneous increase in the level of alpha-IF and IgG which, however, did not always correlate strictly with the course of the disease and the kind of preparation used.
Pritsker
A D
AD
Grigorian
S S
SS
Onufrieva
S S
SS
Chireshkin
D G
DG
Ershov
F I
FI
D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007136:Immunoglobulins / Q000097:blood*; D007370:Interferon Type I / Q000627:therapeutic use*; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D007372:Interferons / Q000097:blood*; D008297:Male; D010212:Papilloma / Q000276:immunology* / Q000628:therapy; D011994:Recombinant Proteins; D012142:Respiratory Tract Neoplasms / Q000276:immunology* / Q000628:therapy
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins; D007370:Interferon Type I; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins; D007372:Interferons
Interferonovyĭ status i tsirkuliruiushchie immunoglobuliny v protsesse interferonoterapii respiratornogo papillomatoza deteĭ.