[The extrasynaptic effect of the neuropeptides vasopressin, oxytocin and vasotocin on the electrically controlled ion channels of the membrane in mollusk neurons].
Extrasynaptic effects of vasopressin, oxytocin, vasotocin on the membrane electrosensitive ionic channels were studied in model experiments using isolated somata from the CNS of mollusc Lymnaea stagnalis. The neuropeptide in concentrations of 1.10(-16)-1.10(-6) mol/l either blocked or induced biphasic dose-dependent effect on amplitudes of the membrane ionic currents.
Artem'ev
I Iu
IIu
Darinskiĭ
Iu A
IuA
D000818:Animals; D002462:Cell Membrane / Q000187:drug effects / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D066298:In Vitro Techniques; D007473:Ion Channels / Q000187:drug effects* / Q000502:physiology; D008195:Lymnaea; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D010121:Oxytocin / Q000494:pharmacology*; D013569:Synapses / Q000187:drug effects*; D014667:Vasopressins / Q000494:pharmacology*; D014668:Vasotocin / Q000494:pharmacology*
D007473:Ion Channels; D014667:Vasopressins; D010121:Oxytocin; D014668:Vasotocin
Vnesinapticheskoe vliianie neĭropeptidov vazopressina, oksitotsina i vazototsina na élektroupravliaemye ionnye kanaly membrany neĭronov molliuska.