title: [Comparison of the results of the treatment of patients with SSPE using various immunomodulating preparations].
abstract: The authors analysed the results of controlled treatment by three methods of patients in the 1st or 2nd phase of SSPE in a randomized group. The groups received: I. Propionibacterium granulosum KP-45 (interferon inducer) + isoprinosine, II--TFX (thymus extract) + isoprinosine, III--only isoprinosine. In all groups the treatment was continued during 6 months. The analysis of the clinical results of these methods failed to demonstrate a statistically significant superiority of any of these methods (among others, due to small number of cases) but an evident statistical tendency was revealed suggesting a better effectiveness of combined treatment (immunostimulator + isoprinosine) in relation to treatment with isoprinosine only. The final evaluation of the results requires further observations of these patients.
authors.affiliation: I Kliniki Neurologicznej Instytutu Psychiatrii i Neurologii, Warszawie.
authors.forename: W
authors.initials: W
authors.lastname: Sobczyk
authors.forename: J
authors.initials: J
authors.lastname: Kulczycki
authors.forename: E
authors.initials: E
authors.lastname: Piłkowska
authors.forename: B
authors.initials: B
authors.lastname: Iwińska
authors.forename: D
authors.initials: D
authors.lastname: Milewska
authors.forename: S
authors.initials: S
authors.lastname: Szmigielski
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage*; D000293:Adolescent; D000328:Adult; D002648:Child; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007542:Inosine Pranobex / Q000008:administration & dosage*; D007369:Interferon Inducers / Q000008:administration & dosage*; D008297:Male; D011424:Propionibacterium; D013344:Subacute Sclerosing Panencephalitis / Q000188:drug therapy / Q000276:immunology / Q000628:therapy*; D013949:Thymus Extracts / Q000008:administration & dosage*; D014020:Tissue Extracts / Q000008:administration & dosage*
chemical_list: D000276:Adjuvants, Immunologic; D007369:Interferon Inducers; C019108:TFX; D013949:Thymus Extracts; D014020:Tissue Extracts; D007542:Inosine Pranobex
vernacular_title: Porównanie wyników leczenia chorych na SSPE róznymi preparatami immunomodulujacymi.