Computer-assisted image analysis of nucleolar organizer regions (NORs): a pilot study of astrocytomas and glioblastomas.
Computer-assisted image analysis was used to measure nucleolar organizer regions (NORs) of 22 astrocytomas and glioblastomas. Image analysis provides reproducible information about number and size of NORs together with further karyometric data, which can be compared and processed with other patient-related data. Our study exhibits a statistical relationship between number and size of NORs and malignancy of the measured gliomas.
Martin
H
H
Institute of Pathology, Humboldt University (Charité), Berlin, F.R.G.
Beil
M
M
Hufnagl
P
P
Wolf
G
G
Korek
G
G
D001254:Astrocytoma / Q000648:ultrastructure*; D001932:Brain Neoplasms / Q000648:ultrastructure*; D005910:Glioma / Q000648:ultrastructure*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007621:Karyotyping; D009697:Nucleolus Organizer Region / Q000648:ultrastructure*; D010865:Pilot Projects; D013194:Staining and Labeling