title: [Selection of antigenic variants of the influenza virus on the cells of different hosts].
abstract: Antigenic differences were found in influenza B virus variants isolated and propagated in different systems: chick embryos (E variants) and MDCK cell culture (M variants). The antigenic differences in M and E variants were detected in HI tests with polyclonal mouse sera and monoclonal antibodies as well as in biological neutralization tests in chick embryos and MDCK cell culture, and confirmed when M and E variants were used as antigens for antibody detection in human sera. By protein mobility in PAGE, M and E variants did not differ from each other and were also identical with the reference B/Victoria/87 strain.
authors.forename: S F
authors.initials: SF
authors.lastname: Shenderovich
authors.forename: L V
authors.initials: LV
authors.lastname: Feklisova
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Smirnov
authors.forename: M A
authors.initials: MA
authors.lastname: Kuznetsova
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal; D000940:Antigenic Variation / Q000276:immunology*; D000956:Antigens, Viral / Q000032:analysis*; D004591:Electrophoresis, Polyacrylamide Gel; D000939:Epitopes / Q000032:analysis; D006382:Hemadsorption / Q000276:immunology; D006385:Hemagglutination Inhibition Tests; D006389:Hemagglutinins, Viral / Q000276:immunology; D006801:Humans; D009980:Influenza A virus / Q000276:immunology*; D051379:Mice; D009500:Neutralization Tests; D051381:Rats; D014764:Viral Proteins / Q000032:analysis
chemical_list: D000911:Antibodies, Monoclonal; D000956:Antigens, Viral; D000939:Epitopes; D006389:Hemagglutinins, Viral; D014764:Viral Proteins
vernacular_title: Selektsiia antigennykh variantov virusa grippa na kletkakh raznykh khoziaev.