title: Electrolyte transport in the lungs.
abstract: The crucial physiologic role of such transport is illustrated by cystic fibrosis. In that lethal genetic disease, transepithelial sodium absorption and chloride secretion are respectively increased and decreased, and pulmonary mucus is dehydrated. Mechanisms that regulate normal sodium and chloride movement are discussed, as are the derangements in cystic fibrosis.
authors.affiliation: Howard Hughes Medical Institute, University of Iowa, Iowa City.
authors.forename: H A
authors.initials: HA
authors.lastname: Berger
authors.forename: M J
authors.initials: MJ
authors.lastname: Welsh
mesh_terms: D000584:Amiloride / Q000494:pharmacology; D002712:Chlorides / Q000378:metabolism*; D003550:Cystic Fibrosis / Q000201:enzymology / Q000378:metabolism / Q000503:physiopathology*; D004232:Diuretics / Q000494:pharmacology; D006801:Humans; D007473:Ion Channels / Q000187:drug effects / Q000502:physiology; D008168:Lung / Q000033:anatomy & histology / Q000201:enzymology / Q000378:metabolism / Q000502:physiology*; D010042:Ouabain / Q000494:pharmacology; D015221:Potassium Channels / Q000187:drug effects / Q000502:physiology*; D015222:Sodium Channels / Q000187:drug effects / Q000502:physiology*; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism
chemical_list: D002712:Chlorides; D004232:Diuretics; D007473:Ion Channels; D015221:Potassium Channels; D015222:Sodium Channels; D010042:Ouabain; D000584:Amiloride; D000254:Sodium-Potassium-Exchanging ATPase