[Experimental study of protease C--proteolytic enzyme of microbial origin].
The specific activity of protease C, a proteolytic enzyme isolated from Acremonium chrysogenum was studied under experimental conditions. Protease C was shown to lyse necrotic biological substrates (dry crusts of burn wounds) and blood clots. By the nature of the effect protease C was analogous to terrilytin and by the level of the effect it was superior in some experiments. Protease C was low toxic and had no mutagenic action.
Dolgova
G V
GV
Berezhinskaia
V V
VV
Svinogeeva
T P
TP
Krest'ianova
I N
IN
D000164:Acremonium / Q000201:enzymology*; D000681:Amylases / Q000096:biosynthesis / Q000627:therapeutic use*; D000818:Animals; D001688:Biological Products / Q000627:therapeutic use; D002056:Burns / Q000628:therapy*; D004195:Disease Models, Animal; D004338:Drug Combinations; D010450:Endopeptidases / Q000096:biosynthesis / Q000627:therapeutic use*; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D010447:Peptide Hydrolases / Q000096:biosynthesis / Q000627:therapeutic use*; D051381:Rats; D013927:Thrombosis / Q000628:therapy*
D001688:Biological Products; D004338:Drug Combinations; D005343:Fibrinolytic Agents; C009402:amylase, phosphates, proteases drug combinations; D000681:Amylases; D010450:Endopeptidases; D010447:Peptide Hydrolases
Eksperimental'noe izuchenie proteazy C--proteoliticheskogo fermenta mikrobnogo proiskhozhdeniia.