HLA type is not indicative for the effect of thymectomy in myasthenia gravis.
The frequency of HLA types in a selected group of 40 patients with myasthenia gravis in relation to the effect of thymectomy and also to gender, and thymus histology was studied. As generally described we found a significant increase in the frequency of HLA-A1, HLA-B8, HLA-DR3 and HLA-DQ2 in the total group. There were no further differences between subgroups of patients, which demonstrates that HLA type is not indicative for the effect of thymectomy in myasthenia gravis.
Kuks
J B
JB
Department of Neurology, University Hospital Groningen, Netherlands.
Lems
S P
SP
Oosterhuis
H J
HJ
D000328:Adult; D005260:Female; D015234:HLA-A Antigens / Q000032:analysis*; D015235:HLA-B Antigens / Q000032:analysis*; D006683:HLA-DQ Antigens / Q000032:analysis*; D006684:HLA-DR Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D009157:Myasthenia Gravis / Q000276:immunology / Q000601:surgery*; D013934:Thymectomy
D015234:HLA-A Antigens; D015235:HLA-B Antigens; D006683:HLA-DQ Antigens; D006684:HLA-DR Antigens