title: [Pain treatment in advanced head and neck tumors. Pilot study with continuous subcutaneous administration of morphine].
abstract: In the pain treatment of patients with incurable head and neck tumors it may be difficult to provide adequate oral drug therapy in the advanced stages. In these cases continuous subcutaneous application of morphine by means of external infusors is an alternative. This mode of application was investigated in the long-term treatment of 20 patients with pain that had been therapyresistent until then. Producing sufficient analgesia and having, all told, comparable side-effects, this method was experienced by all patients as being more agreeable than the previously used oral mode of application. Technical simplicity of handling makes this safe and effective treatment concept also a valuable means for outpatient care in tumor clinics.
authors.affiliation: Klinik und Poliklinik für Anasthesiologie und Operative Intensivmedizin-Schmerzambulanz der Westfälischen Wilhelms-Universität Münster.
authors.forename: I
authors.initials: I
authors.lastname: Gralow
authors.forename: W
authors.initials: W
authors.lastname: von Hornstein
authors.forename: J
authors.initials: J
authors.lastname: Hidding
mesh_terms: D005260:Female; D006258:Head and Neck Neoplasms / Q000188:drug therapy*; D006801:Humans; D007279:Injections, Subcutaneous; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage*; D010148:Intractable Pain / Q000188:drug therapy*; D010166:Palliative Care / Q000379:methods*; D010865:Pilot Projects
chemical_list: D009020:Morphine
vernacular_title: Schmerzbehandlung in fortgeschrittenen Stadien von Kopf-Hals-Tumoren. Eine Pilotstudie zur kontinuierlichen subkutanen Morphinapplikation.