Isolation and characterization of galanin from sheep brain.
Galanin is a well-known, naturally occurring peptide, which has been characterized from both cDNA sequences and direct peptide analysis. Previous structural studies have been made using intestinally derived material. This report concerns galanin isolation from sheep brain and its sequence determination. Sheep galanin shows great similarity to pig galanin, differing by one amino acid substitution, that being a histidine residue, as in cow and rat galanin, instead of tyrosine at position 26.
Sillard
R
R
Department of Biochemistry II, Karolinska Institutet, Stockholm, Sweden.
Langel
U
U
Jörnvall
H
H
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001923:Brain Chemistry; D002851:Chromatography, High Pressure Liquid; D019004:Galanin; D008969:Molecular Sequence Data; D009479:Neuropeptides / Q000302:isolation & purification* / Q000378:metabolism; D010449:Peptide Mapping; D010455:Peptides / Q000302:isolation & purification* / Q000378:metabolism; D011869:Radioligand Assay; D012689:Sequence Homology, Nucleic Acid; D012756:Sheep; D014357:Trypsin
D000596:Amino Acids; D009479:Neuropeptides; D010455:Peptides; D019004:Galanin; D014357:Trypsin