title: Structure of mouse myelin-associated glycoprotein gene.
abstract: The mouse myelin-associated glycoprotein gene was isolated from a mouse gene library. This gene was split into 13 exons distributed about 15 kb in length. Each extracellular immunoglobulin-related domain was encoded by a single exon, and RNA splicing between those exons occurred between the first and second nucleotides of the junctional codon, the features of which are conserved in most of the genes of the immunoglobulin superfamily. The sequence of the 5'-flanking region appeared to have some regions homologous to other myelin proteins, which suggested that they were possible cis-elements for specific expression of oligodendrocytes.
authors.affiliation: Department of Neurology, Niigata University, Japan.
authors.forename: R
authors.initials: R
authors.lastname: Nakano
authors.forename: N
authors.initials: N
authors.lastname: Fujita
authors.forename: S
authors.initials: S
authors.lastname: Sato
authors.forename: T
authors.initials: T
authors.lastname: Inuzuka
authors.forename: K
authors.initials: K
authors.lastname: Sakimura
authors.forename: H
authors.initials: H
authors.lastname: Ishiguro
authors.forename: M
authors.initials: M
authors.lastname: Mishina
authors.forename: T
authors.initials: T
authors.lastname: Miyatake
mesh_terms: D000818:Animals; D001483:Base Sequence; D004247:DNA / Q000235:genetics; D005091:Exons; D015723:Gene Library; D005796:Genes; D007438:Introns; D051379:Mice; D008969:Molecular Sequence Data; D009185:Myelin Proteins / Q000235:genetics*; D018992:Myelin-Associated Glycoprotein; D015183:Restriction Mapping; D012689:Sequence Homology, Nucleic Acid
chemical_list: D009185:Myelin Proteins; D018992:Myelin-Associated Glycoprotein; D004247:DNA