ACE inhibitors in the diagnosis of renovascular hypertension.
Effective therapy is available but the diagnosis of renovascular hypertension is often elusive. Those affected constitute a minority of the hypertensive population, and traditional screening tests have poor sensitivity and specificity. The merits and limitations of the captopril challenge test and the captopril renogram, alone or in combination, are discussed.
Wilcox
C S
CS
Division of Nephrology, Hypertension, and Transplantation, University of Florida College of Medicine, Gainesville.
D002216:Captopril / Q000494:pharmacology; D003663:Decision Trees; D005919:Glomerular Filtration Rate / Q000187:drug effects; D006801:Humans; D006978:Hypertension, Renovascular / Q000175:diagnosis* / Q000503:physiopathology / Q000517:prevention & control; D008403:Mass Screening / Q000379:methods / Q000592:standards; D011866:Radioisotope Renography / Q000592:standards; D012083:Renin / Q000097:blood / Q000187:drug effects; D012680:Sensitivity and Specificity; D016284:Technetium Tc 99m Pentetate
D002216:Captopril; D012083:Renin; D016284:Technetium Tc 99m Pentetate