title: Fluorescence, CD, and NMR studies on spantide, a bombesin and substance P antagonist.
abstract: The conformational properties of spantide [(D-Arg, D-Trp, Leu) substance P] have been studied by fluorescence, CD, and nmr techniques. The fluorescence, CD, and nmr parameters in different solvents and in a micellar environment (SDS) are compared with the data collected for bombesin. A preliminary investigation on [D-Pro] spantide is also reported.
authors.affiliation: Institute of Industrial Chemistry, University of Padova, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Di Bello
authors.forename: A
authors.initials: A
authors.lastname: Scatturin
authors.forename: G
authors.initials: G
authors.lastname: D'Auria
authors.forename: M
authors.initials: M
authors.lastname: Gargiulo
authors.forename: L
authors.initials: L
authors.lastname: Paolillo
authors.forename: E
authors.initials: E
authors.lastname: Trivellone
authors.forename: R
authors.initials: R
authors.lastname: De Castiglione
mesh_terms: D000595:Amino Acid Sequence; D001839:Bombesin / Q000737:chemistry*; D002942:Circular Dichroism; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D012996:Solutions; D013050:Spectrometry, Fluorescence; D013373:Substance P / Q000031:analogs & derivatives* / Q000737:chemistry
chemical_list: D012996:Solutions; D013373:Substance P; C042867:spantide; D001839:Bombesin