title: RNA editing.
abstract: Since its discovery, RNA editing in kinetoplastid mitochondria has proven a fascinating topic of study, and the last one and a half years have witnessed enormous advances in our understanding of this unprecedented form of RNA processing. The information flow in this RNA editing, once considered a candidate for defying the central dogma, is now known to conform to the DNA-to-RNA-to-protein paradigm, with the novel feature that the sequence of an edited region is not actually present in any DNA segment, but instead derives by a novel micro-interdigitating of information encoded in multiple DNA regions.
authors.affiliation: Johns Hopkins University, Baltimore, Maryland.
authors.forename: B
authors.initials: B
authors.lastname: Sollner-Webb
mesh_terms: D008928:Mitochondria / Q000378:metabolism*; D008957:Models, Genetic; D012313:RNA / Q000235:genetics / Q000378:metabolism*; D012323:RNA Processing, Post-Transcriptional
chemical_list: D012313:RNA