title: The regional distribution of thyrotropin releasing hormone, leu-enkephalin, met-enkephalin, substance P, somatostatin and cholecystokinin in the rat brain and pituitary.
abstract: There was no apparent difference in the regional distribution of neuropeptides in the brain of male and female rats. The highest levels of immunoreactive leu-enkephalin, TRH, substance P and somatostatin were found in the hypothalamus, while the striatum and the cerebral cortex had the highest concentrations of met-enkephalin and cholecystokinin respectively. The lowest concentrations of these were found in the cerebellum. Enkephalins (cerebral cortex), substance P (cerebral cortex and brain stem), and somatostatin (brain stem and striatum) showed higher level in the female while enkephalin and substance P contents in the anterior pituitary were higher in the male.
authors.affiliation: Department of Physiology, Faculty of Medicine, University of Hong Kong.
authors.forename: F
authors.initials: F
authors.lastname: Tang
authors.forename: W S
authors.initials: WS
authors.lastname: Man
mesh_terms: D000818:Animals; D001923:Brain Chemistry; D001933:Brain Stem / Q000737:chemistry; D002766:Cholecystokinin / Q000032:analysis*; D003342:Corpus Striatum / Q000737:chemistry; D004743:Enkephalin, Leucine / Q000032:analysis; D004744:Enkephalin, Methionine / Q000032:analysis; D005260:Female; D007031:Hypothalamus / Q000737:chemistry; D008297:Male; D009479:Neuropeptides / Q000032:analysis*; D010902:Pituitary Gland / Q000737:chemistry*; D051381:Rats; D011919:Rats, Inbred Strains; D013004:Somatostatin / Q000032:analysis; D013373:Substance P / Q000032:analysis; D013973:Thyrotropin-Releasing Hormone / Q000032:analysis
chemical_list: D009479:Neuropeptides; D013373:Substance P; D013004:Somatostatin; D004744:Enkephalin, Methionine; D004743:Enkephalin, Leucine; D013973:Thyrotropin-Releasing Hormone; D002766:Cholecystokinin