[Effectiveness of single intravenous administration of cordarone, ethacizine and obsidan in ventricular extrasystole in patients with chronic alcoholism during withdrawal].
Antiarrhythmic effects of cordarone, ethacizine, and obsidan were evaluated in 30 patients with chronic alcoholism in whom premature ventricular contractions were recorded at a rate of at least of 5 per minute by 30-minute ECG monitoring when they were admitted to a narcologic hospital, having the alcohol withdrawal syndrome. Cordarone, ethacizine, and obsidan were found to reduce the total number of premature ventricular contractions by 90% or more within an hour after their single intravenous injection in 80, 100, and 50% of the patients, respectively.
Karaush
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AP
Gorgaslidze
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Smetnev
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AS
D000328:Adult; D000437:Alcoholism / Q000534:rehabilitation*; D000638:Amiodarone / Q000008:administration & dosage*; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage*; D005117:Cardiac Complexes, Premature / Q000139:chemically induced / Q000188:drug therapy*; D000431:Ethanol / Q000009:adverse effects*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D010640:Phenothiazines / Q000008:administration & dosage*; D011433:Propranolol / Q000008:administration & dosage*; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy*
D000889:Anti-Arrhythmia Agents; D010640:Phenothiazines; D000431:Ethanol; D011433:Propranolol; C046818:ethacizine; D000638:Amiodarone
Effektivnost' odnokratnogo vnutrivennogo vvedeniia kordarona, étatsizina i obzidana pri zheludochkovoĭ ékstrasistolii u bol'nykh khronicheskim alkogolizmom v sostoianii abstinentsii.