Meningoencephalitis in a neonate congenitally infected with human immunodeficiency virus type 1.
A newborn infant born to a mother infected with human immunodeficiency virus type 1 had acute meningoencephalitis on the second day of life. Human immunodeficiency virus type 1 was isolated from the plasma, cerebrospinal fluid, and peripheral blood mononuclear cells. Specific IgM for human immunodeficiency virus type 1 was detected by an enzyme-linked immunosorbent assay antibody-capture technique in cord blood and in serum obtained 3 weeks later. We believe that the meningoencephalitis was caused by human immunodeficiency virus type 1 acquired in utero.
Srugo
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I
Division of Pediatric Infectious Diseases, Ahmanson Pediatric Center, Los Angeles, CA 90048.
Wittek
A E
AE
Israele
V
V
Brunell
P A
PA
D000328:Adult; D005260:Female; D015658:HIV Infections / Q000151:congenital* / Q000635:transmission; D015497:HIV-1; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008431:Maternal-Fetal Exchange; D008590:Meningoencephalitis / Q000209:etiology*; D011247:Pregnancy