title: Large focal defect on liver/spleen scan caused by fatty liver and masquerading as neoplasm.
abstract: Focal fatty infiltration of the liver may be mistaken for metastatic disease, primary tumor or other space-occupying lesions on CT or ultrasound. Usually, a 99mTc-sulfur colloid scan is sensitive in documenting the presence of Kupffer's cell in such a process. We present a case that was suggestive of focal fatty infiltrate on a CT scan, nondiagnostic on ultrasound, and seen as a large focal defect on the 99mTc-sulfur colloid liver/spleen scan. A 133Xe inhalation study, however, did show uptake in the area of fatty infiltration. A needle biopsy confirmed the diagnosis.
authors.affiliation: Department of Nuclear Medicine, Lutheran General Hospital, Park Ridge, Illinois 60068.
authors.forename: N
authors.initials: N
authors.lastname: Khedkar
authors.forename: B
authors.initials: B
authors.lastname: Pestika
authors.forename: H
authors.initials: H
authors.lastname: Rosenblate
authors.forename: C
authors.initials: C
authors.lastname: Martinez
mesh_terms: D005234:Fatty Liver / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008875:Middle Aged; D011877:Radionuclide Imaging; D013154:Spleen / Q000000981:diagnostic imaging; D013671:Technetium Tc 99m Sulfur Colloid; D014980:Xenon Radioisotopes
chemical_list: D014980:Xenon Radioisotopes; D013671:Technetium Tc 99m Sulfur Colloid