title: [Multivariate analysis for the understanding of typical diabetic hemostasis criteria. 2. Prevalent thrombocytic markers].
abstract: Various thrombocyte functions and metabolic criteria were investigated in 309 test persons, among them 198 Patients affected with diabetes mellitus, 67 of type I and 131 of type II as well as 111 healthy control persons. From the variety of these factors an optimal amount was determined by means of the statistical method of multivariance analysis separating both types of diabetes and healthy control persons. In addition to haemoglobin A1 concentration, thrombocyte parameters have been found together with the degree of capillary fragility, adrenalin-induced aggregation, platelet aggregation test and clot retraction, which allow individuals to be assigned diagnostically to various groups of test persons. Thus, thrombocyte functions found in both types of diabetes and normal persons exhibit differences which may contribute to a diagnostic classification.
authors.affiliation: Klinik für Innere Medizin, Arbeitsgruppe EDV, Friedrich-Schiller-Universität Jena.
authors.forename: G
authors.initials: G
authors.lastname: Syrbe
authors.forename: H
authors.initials: H
authors.lastname: Schröder
authors.forename: E
authors.initials: E
authors.lastname: Keil
authors.forename: A
authors.initials: A
authors.lastname: Jütte
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D001792:Blood Platelets / Q000502:physiology*; D002198:Capillary Fragility; D003018:Clot Retraction; D003920:Diabetes Mellitus / Q000097:blood*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000097:blood; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D015999:Multivariate Analysis; D010974:Platelet Aggregation; D012016:Reference Values
chemical_list: D015415:Biomarkers; D006442:Glycated Hemoglobin
vernacular_title: Multivarianzanalyse zur Erfassung diabetestypischer Hämostasekriterien. Teil 2: Vorwiegend trombozytäre Merkmale.