The structural polypeptide VP3 of infectious bursal disease virus carries group- and serotype-specific epitopes.
Two independent non-overlapping epitopes could be demonstrated on the structural protein VP3 of infectious bursal disease virus by non-neutralizing monoclonal antibodies produced against serotypes I and II. Both serotypes have one epitope in common, whereas the second epitope is distinct for serotype I and serotype II.
Oppling
V
V
Institut für Virologie, Justus-Liebig-Universität Giessen, Germany.
Müller
H
H
Becht
H
H
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D000918:Antibody Specificity; D000956:Antigens, Viral / Q000032:analysis* / Q000276:immunology; D003429:Cross Reactions; D004797:Enzyme-Linked Immunosorbent Assay; D000939:Epitopes / Q000032:analysis / Q000276:immunology; D006825:Hybridomas; D015151:Immunoblotting; D007243:Infectious bursal disease virus / Q000145:classification / Q000276:immunology*; D015531:Radioimmunoprecipitation Assay; D012703:Serotyping; D015678:Viral Structural Proteins / Q000276:immunology*
D000911:Antibodies, Monoclonal; D000956:Antigens, Viral; D000939:Epitopes; D015678:Viral Structural Proteins