[The combined radionuclide diagnosis of rectal cancer recurrences].
Of 153 patients with confirmed rectal cancer CEA was recorded in 139 (90.8%); erroneous results were noted in 14 (9.2%) patients; in scintigraphy with 67Ga-citrate and 111In-bleomycin diagnoses coincided in 147 (96.1%) patients, and false-negative results were noted in 6 (3.9%) patients. During the investigation 16 patients who had undergone radical operation with any signs of recurrence and 36 patients with suspected tumor recurrence, scintigraphic false-positive results were observed in 12.5 and 30.6% patients, and a false-positive increase in the CEA titer was observed in 12.5 and 11.1%. Of 11 patients with false-positive scintigraphic results a rise of the CEA level was noted in 2 cases making it possible to rule out with a great degree of assurance the presence of a recurrent tumor. The results obtained suggest the appropriateness of the combination of these methods to improve the diagnosis of rectal cancer recurrences.
Lenskaia
O P
OP
KUznetsova
L F
LF
Ozhiganov
E L
EL
Bogdasarov
Iu B
IuB
D000293:Adolescent; D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood; D001761:Bleomycin / Q000031:analogs & derivatives; D002272:Carcinoembryonic Antigen / Q000097:blood; D002951:Citrates; D019343:Citric Acid; D005188:False Negative Reactions; D005189:False Positive Reactions; D005710:Gallium Radioisotopes; D006801:Humans; D007205:Indium Radioisotopes; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging*; D009942:Organometallic Compounds; D011863:Radioimmunoassay; D011877:Radionuclide Imaging; D012004:Rectal Neoplasms / Q000000981:diagnostic imaging*; D012007:Rectum / Q000000981:diagnostic imaging
D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D002951:Citrates; D005710:Gallium Radioisotopes; D007205:Indium Radioisotopes; D009942:Organometallic Compounds; C047120:indium-bleomycin; D001761:Bleomycin; D019343:Citric Acid
Kompleksnaia radionuklidnaia diagnostika raka priamoĭ kishki.