Confirmation of the assignment of the vitronectin (VNRA) and fibronectin (FNRA) receptor alpha-subunits.
The receptors for the extracellular structural components fibronectin and vitronectin each consist of two subunits called alpha and beta. Using human-rodent somatic cell hybrids and cDNA probes corresponding to the alpha-subunits, we have confirmed the mapping of the fibronectin receptor (FNRA) to chromosome 12 and the vitronectin receptor (VNRA) to chromosome 2.
Spurr
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Human Genetic Resources, Imperial Cancer Research Fund, Clare Hall Laboratories, Potters Bar, Herts, UK.
Rooke
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L
D000818:Animals; D015139:Blotting, Southern; D002874:Chromosome Mapping; D002881:Chromosomes, Human, Pair 12; D002889:Chromosomes, Human, Pair 2; D005353:Fibronectins / Q000378:metabolism*; D006801:Humans; D006822:Hybrid Cells; D016023:Integrins / Q000378:metabolism*; D017469:Receptors, Fibronectin; D011971:Receptors, Immunologic / Q000235:genetics* / Q000378:metabolism; D019030:Receptors, Vitronectin
D005353:Fibronectins; D016023:Integrins; D017469:Receptors, Fibronectin; D011971:Receptors, Immunologic; D019030:Receptors, Vitronectin