[The humoral immunity system of mice with experimental slow influenzal infection].
The status of the interferon system and level of immunoglobulins were studied in C57BL6 mice with slow influenza infection. These mice showed signs of immunosuppression: low endogenous interferon production, synthesis of alpha- and gamma-interferon by splenocytes of these mice in vitro 4-8 times lower than by those of the controls, lower levels of IgG in the blood serum. These data indicate general suppression of humoral immunity.
Mirchink
E P
EP
Babaiants
A A
AA
Kuznetsov
V P
VP
Zuev
V A
VA
Aleshkin
V A
VA
D000375:Aging / Q000276:immunology; D000818:Animals; D000917:Antibody Formation / Q000276:immunology; D005260:Female; D007108:Immune Tolerance / Q000276:immunology; D007136:Immunoglobulins / Q000032:analysis; D007372:Interferons / Q000032:analysis / Q000276:immunology; D051379:Mice; D008810:Mice, Inbred C57BL; D009976:Orthomyxoviridae Infections / Q000276:immunology*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D012897:Slow Virus Diseases / Q000276:immunology*
D007136:Immunoglobulins; D007372:Interferons
Sostoianie sistemy gumoral'nogo immuniteta u mysheĭ pri éksperimental'noĭ medlennoĭ grippoznoĭ infektsii.