title: Paget's disease: current concepts.
abstract: The curious geographic variations in the prevalence of Paget's disease remain unexplained and the viral hypothesis remains unproved. An association between transient hyperphosphataemia of infancy and subsequent Paget's disease has not been established. Some 5% of Pagetic patients have hyperparathyroidism although the mechanism of this apparent association remains unknown. Several agents are available for the medical treatment of Paget's disease but there is a lack of consensus concerning therapeutic aims.
authors.affiliation: Department of Medicine, University of Sydney, New South Wales, Australia.
authors.forename: S
authors.initials: S
authors.lastname: Posen
mesh_terms: D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D001842:Bone and Bones / Q000473:pathology; D004285:Dogs; D006801:Humans; D010001:Osteitis Deformans / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology / Q000473:pathology
chemical_list: D000469:Alkaline Phosphatase