title: Structural modifications of acidic fibroblast growth factor alter activity, stability, and heparin dependence.
authors.affiliation: Department of Biochemistry, Merck Research Laboratories, Rahway, New Jersey 07065.
authors.forename: K A
authors.initials: KA
authors.lastname: Thomas
authors.forename: S
authors.initials: S
authors.lastname: Ortega
authors.forename: D
authors.initials: D
authors.lastname: Soderman
authors.forename: M T
authors.initials: MT
authors.lastname: Schaeffer
authors.forename: J
authors.initials: J
authors.lastname: DiSalvo
authors.forename: G
authors.initials: G
authors.lastname: Gimenez-Gallego
authors.forename: D
authors.initials: D
authors.lastname: Linemeyer
authors.forename: L
authors.initials: L
authors.lastname: Kelly
authors.forename: J
authors.initials: J
authors.lastname: Menke
mesh_terms: D016475:3T3 Cells; D000595:Amino Acid Sequence; D000818:Animals; D003545:Cysteine / Q000737:chemistry; D004220:Disulfides / Q000737:chemistry; D016220:Fibroblast Growth Factor 1 / Q000737:chemistry / Q000502:physiology*; D006801:Humans; D066298:In Vitro Techniques; D051379:Mice; D008934:Mitogens; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D011994:Recombinant Proteins; D016415:Sequence Alignment; D013329:Structure-Activity Relationship
chemical_list: D004220:Disulfides; D008934:Mitogens; D011994:Recombinant Proteins; D016220:Fibroblast Growth Factor 1; D003545:Cysteine