Salivary gland antigens of Ixodes dammini are glycoproteins that have interspecies cross-reactivity.
Serum from rabbits and rats exposed to Ixodes dammini adults and larvae, respectively, contain antibodies to a large number of antigens in salivary gland homogenates from adult ticks that cross react with the antigens of a closely related species, Ixodes scapularis, and significantly with Dermacentor variabilis antigens. The salivary gland antigens of I. dammini are glycoproteins composed of both N- and O-linked carbohydrate chains. The antigenic determinants reside in both the polypeptide and carbohydrate chains.
Wheeler
C M
CM
State of New York Department of Health, Stony Brook 11794.
Coleman
J L
JL
Benach
J L
JL
D000818:Animals; D000906:Antibodies / Q000097:blood*; D000941:Antigens / Q000737:chemistry / Q000276:immunology*; D001096:Arachnid Vectors / Q000276:immunology*; D015153:Blotting, Western; D003429:Cross Reactions; D003870:Dermacentor / Q000276:immunology; D004591:Electrophoresis, Polyacrylamide Gel; D000939:Epitopes / Q000032:analysis; D005260:Female; D006023:Glycoproteins / Q000737:chemistry / Q000276:immunology*; D011817:Rabbits; D051381:Rats; D013987:Ticks / Q000276:immunology*
D000906:Antibodies; D000941:Antigens; D000939:Epitopes; D006023:Glycoproteins