title: Hb F-Catalonia or alpha 2G gamma(2)15(A12)Trp----Arg.
abstract: Hb F-Catalonia, a G gamma chain variant with a Trp----Arg substitution at position gamma 15(A12), was observed in two Spanish newborn babies from Northeastern Spain. Analyses were performed with different reversed phase high performance liquid chromatographic procedures that allowed the identification of the amino acid replacement in only a minute quantity of the isolated G gamma X chain.
authors.affiliation: Department of Cell and Molecular Biology, Medical College of Georgia, Augusta 30912-2100.
authors.forename: D
authors.initials: D
authors.lastname: Plaseska
authors.forename: J B
authors.initials: JB
authors.lastname: Wilson
authors.forename: F
authors.initials: F
authors.lastname: Kutlar
authors.forename: L
authors.initials: L
authors.lastname: Font
authors.forename: M
authors.initials: M
authors.lastname: Baiget
authors.forename: T H
authors.initials: TH
authors.lastname: Huisman
mesh_terms: D000596:Amino Acids / Q000032:analysis; D005319:Fetal Hemoglobin / Q000737:chemistry*; D006455:Hemoglobins, Abnormal / Q000737:chemistry*; D006801:Humans; D007231:Infant, Newborn; D013030:Spain
chemical_list: D000596:Amino Acids; D006455:Hemoglobins, Abnormal; C067965:hemoglobin F Catalonia; D005319:Fetal Hemoglobin