Effects of feeding low protein diet with and without leucine supplementation on protein status of lactating females and their pups.
Female rats were fed low protein diet (10% casein) either as such or supplemented with 3% leucine during pregnancy and lactation. Changes in litter size and the survival rate, growth and protein status of the pups were noted. The milk yield and hepatic and mammary gland protein status of the mothers were also studied. Feeding low protein diet reduced litter size, increased their mortality and resulted in poor growth of the pups. It also resulted in poor hepatic and mammary gland protein status of the mothers, as well as reduced their milk yield. On adding 3% leucine to 10% casein in the diet, the changes observed in the low protein group, did not alter in any manner.
Chugh
K
K
Department of Biochemistry, Medical College, Rohtak.
Kaur
J
J
Saini
A S
AS
Lal
H
H
D000818:Animals; D000833:Animals, Suckling / Q000378:metabolism*; D001835:Body Weight / Q000187:drug effects / Q000502:physiology; D002364:Caseins / Q000008:administration & dosage / Q000494:pharmacology; D004247:DNA / Q000378:metabolism; D004044:Dietary Proteins / Q000008:administration & dosage* / Q000494:pharmacology; D005260:Female; D007774:Lactation / Q000378:metabolism*; D007930:Leucine / Q000494:pharmacology*; D008098:Litter Size; D008099:Liver / Q000033:anatomy & histology; D008297:Male; D008321:Mammary Glands, Animal / Q000378:metabolism; D009929:Organ Size / Q000187:drug effects / Q000502:physiology; D011247:Pregnancy; D011488:Protein Deficiency / Q000378:metabolism; D011506:Proteins / Q000378:metabolism; D012313:RNA / Q000378:metabolism; D051381:Rats
D002364:Caseins; D004044:Dietary Proteins; D011506:Proteins; D012313:RNA; D004247:DNA; D007930:Leucine