title: [Study of chemically modified hemoglobin as an artificial oxygen carrier in the model of hemorrhagic shock in dogs].
abstract: Hemodynamic and gas-transporting properties of the chemically modified hemoglobin solution have been studied on the model of hemorrhagic shock in dog. It has been shown that the polymerized hemoglobin solution exerts the hemodynamic action just as the plasma substitute "polyglucin" does. However, in contrast to the latter, polyhemoglobin circulating in the vascular bed for a prolonged period of time increases the blood oxygen capacity and oxygen delivery to tissues with the resultant increase in body total oxygen taking-up.
authors.forename: E A
authors.initials: EA
authors.lastname: Selivanov
authors.forename: N I
authors.initials: NI
authors.lastname: Kochetygov
authors.forename: K A
authors.initials: KA
authors.lastname: Gerbut
authors.forename: M A
authors.initials: MA
authors.lastname: Azhigirova
authors.forename: E P
authors.initials: EP
authors.lastname: Viazova
authors.forename: A M
authors.initials: AM
authors.lastname: Zeĭnalov
authors.forename: I M
authors.initials: IM
authors.lastname: Bystrova
authors.forename: E I
authors.initials: EI
authors.lastname: Molokovskaia
mesh_terms: D000818:Animals; D001802:Blood Substitutes; D003911:Dextrans; D004285:Dogs; D006439:Hemodynamics; D006454:Hemoglobins; D010100:Oxygen / Q000008:administration & dosage / Q000097:blood; D012771:Shock, Hemorrhagic / Q000503:physiopathology / Q000628:therapy*; D013997:Time Factors
chemical_list: D001802:Blood Substitutes; D003911:Dextrans; D006454:Hemoglobins; C037158:polyhemoglobin; D010100:Oxygen
vernacular_title: Izuchenie khimicheski modifitsirovannogo gemoglobina v kachestve iskusstvennogo perenoschika kisloroda na modeli gemorragicheskogo shoka u sobak.