title: [Dimethyl sulfoxide in the treatment of interstitial cystitis].
abstract: The paper presents the results obtained with endovesical dimethylsulphoxide in the treatment of interstitial cystitis in 30 women. Up to 80% patients showed clinical improvement with an average of 10 installations. Volume of maximal vesical capacity was increased in 24 patients (80%), the increase being greater than 100 cc in 10 cases. Presently, 24 (80%) patients remain under treatment, 14 with one instillation monthly and 10 once every six months. Six patients are fully asymptomatic without treatment after an average symptoms-free interval of 32 months. Since this is directly related to a decrease both in pain and miction frequency, the increase in vesical capacity appears to be a good improvement index. Dimethylsulphoxide in neither a healing nor a definite therapy but it seems to be effective in the management of this unknown disease.
authors.affiliation: Servicio de Urología, Residencia General del Hospital La Fe, Valencia.
authors.forename: J L
authors.initials: JL
authors.lastname: Ruiz
authors.forename: M
authors.initials: M
authors.lastname: Alonso
authors.forename: B
authors.initials: B
authors.lastname: Moreno
authors.forename: G
authors.initials: G
authors.lastname: Server
authors.forename: J M
authors.initials: JM
authors.lastname: Osca
authors.forename: J F
authors.initials: JF
authors.lastname: Jiménez
mesh_terms: D000283:Administration, Intravesical; D000328:Adult; D000368:Aged; D003556:Cystitis / Q000188:drug therapy*; D004121:Dimethyl Sulfoxide / Q000008:administration & dosage / Q000627:therapeutic use*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008875:Middle Aged; D010166:Palliative Care
chemical_list: D004121:Dimethyl Sulfoxide
vernacular_title: Dimetilsulfóxido en el tratamiento de la cistitis intersticial.