The neuropathology of Alzheimer's disease investigated by transplantation of mouse trisomy 16 hippocampal tissues.
This article evaluates the novel application of neural transplantation as a model for studying the neuropathological events associated with Alzheimer's disease and those that have subsequently also been observed in Trisomy 21 (Down syndrome).
Richards
S J
SJ
Dept of Medicine, Addenbrooke's Hospital, Cambridge, UK.
D000544:Alzheimer Disease / Q000473:pathology*; D000818:Animals; D016380:Brain Tissue Transplantation / Q000502:physiology*; D004314:Down Syndrome / Q000473:pathology; D006624:Hippocampus / Q000637:transplantation*; D006801:Humans; D014314:Trisomy