title: [The efficacy of drug therapy in structural lesions of the hair and in diffuse effluvium--comparative double blind study].
abstract: Growth and quality of hair was studied after treatment with Pantogar, another prescription (Verum-2) and placebo for four months in 60 patients with diffuse effluvium capillorum and agnogenic structural alternations of hair. Efficacy was assessed by measurements of swelling, dye-binding and thickness for hair-quality and evaluation of hair-density and trichograms for hair-growth. Statistical analysis of swelling properties and trichogram data indicated that Pantogar was effective, the second preparation improved quality of hair and retarded hair loss. Placebo was ineffective judged by the used parameters. Tolerance of the treatment was good and adverse effects could not be substantiated.
authors.affiliation: Hautklinik der Städt. Kliniken Dortmund Akademisches Lehrkrankenhaus, Universitäts-Hautklinik Witten-Herdecke.
authors.forename: H
authors.initials: H
authors.lastname: Petri
authors.forename: P
authors.initials: P
authors.lastname: Pierchalla
authors.forename: H
authors.initials: H
authors.lastname: Tronnier
mesh_terms: D010129:4-Aminobenzoic Acid / Q000008:administration & dosage*; D000505:Alopecia / Q000188:drug therapy*; D062365:Aminobenzoates / Q000008:administration & dosage*; D002118:Calcium / Q000008:administration & dosage; D003545:Cysteine / Q000008:administration & dosage*; D003553:Cystine / Q000008:administration & dosage; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D006201:Hair Diseases / Q000188:drug therapy*; D006801:Humans; D007633:Keratins / Q000008:administration & dosage*; D008297:Male; D010205:Pantothenic Acid / Q000008:administration & dosage*; D013831:Thiamine / Q000008:administration & dosage*; D015002:Yeast, Dried / Q000008:administration & dosage*
chemical_list: D062365:Aminobenzoates; D004338:Drug Combinations; C068637:calcium D-pantothenate, L-cysteine drug combination; C068639:pantogar; D010205:Pantothenic Acid; D003553:Cystine; D007633:Keratins; D003545:Cysteine; D002118:Calcium; D010129:4-Aminobenzoic Acid; D013831:Thiamine
vernacular_title: Die Wirksamkeit einer medikamentösen Therapie bei Haarstrukturschäden und diffusen Effluvien--vergleichende Doppelblindstudie.