The use of oral antibiotics in daily clinical practice.
In the treatment of infectious diseases in daily clinical practice, the physician is faced with a wide choice of antibiotics. Rational antibiotic use requires knowledge of the pathogens causing disease at that site, and the prevalence of resistance. In outpatient respiratory tract infection, for example, 3 pathogens, Branhamella (Moraxella) catarrhalis, Haemophilus influenzae and Streptococcus pneumoniae, predominate, beta-Lactamase production by the first 2 is a significant factor in antibiotic selection for respiratory tract infection. Empirical antibiotics are selected for efficacy, cost-effectiveness, safety and patient compliance.
Verghese
A
A
Texas Tech Regional Academic Health Center, El Paso.
D000284:Administration, Oral; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D012141:Respiratory Tract Infections / Q000188:drug therapy
D000900:Anti-Bacterial Agents