title: Fate of explanted ICD patients.
abstract: Of 56 consecutive patients who underwent an initial AICD implantation at our center, we analyzed eight patients who subsequently had their units explanted and not replaced by other antitachycardia devices. The mean age was 57.8 years, mean ejection fraction was 28.4%; six patients had coronary disease and two had cardiomyopathy. The presenting arrhythmia was sudden death in four patients and sustained ventricular tachycardia in four others. Mean follow-up from implant to explant was 25 +/- 22 months, and 22 +/- 10 months from explant to end of follow-up. Reasons for explantation were: infection in five patients, lead fracture in one patient, battery depletion in one patient, and one patient underwent cardiac transplantation. Devices were not reimplanted because of: patient refusal in three patients, physician discretion in two patients (one recurrent infection, one received no shocks over 24 months), cardiac transplantation in one patient, ablation of VT focus in one patient, and one patient died while being treated for infection. Three patients died 2, 21, and 26 months after device explantation of nonsudden cardiac, sudden cardiac and noncardiac causes, respectively.
  
  
  CONCLUSIONS
  Preoperative clinical parameters were not indicative of a lower risk of arrhythmic events in these patients as compared to the general population of AICD implantees. Of eight patients, two received alternate nonmedical therapy, one died while receiving treatment for a device-related infection; of the five remaining patients none died of cardiac causes. Termination of AICD therapy for malignant ventricular arrhythmias does not imply imminent sudden cardiac death for most patients treated by alternate modes of therapy.
authors.affiliation: Department of Cardiothoracic Surgery, Montefiore Medical Center, Bronx, New York 10467.
authors.forename: P
authors.initials: P
authors.lastname: Zilo
authors.forename: J N
authors.initials: JN
authors.lastname: Gross
authors.forename: D
authors.initials: D
authors.lastname: Johnston
authors.forename: J D
authors.initials: JD
authors.lastname: Fisher
authors.forename: S
authors.initials: S
authors.lastname: Furman
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D003645:Death, Sudden / Q000453:epidemiology*; D004554:Electric Countershock / Q000295:instrumentation*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019736:Prostheses and Implants; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000453:epidemiology; D013610:Tachycardia / Q000401:mortality / Q000628:therapy*; D013997:Time Factors; D016312:Treatment Refusal
chemical_list: D000889:Anti-Arrhythmia Agents