title: Spinocerebellar projection in the meander tail mutant mouse: organization in the granular posterior lobe and the agranular anterior lobe.
abstract: The cerebellum of the mutant mouse, meander tail, is characterized by normal cytoarchitecture posteriorly and abnormal, agranular cortex anteriorly. Anterograde WGA-HRP tracing analysis of the spinocerebellar projection reveals typical mossy fiber labeling posteriorly in lobule VIII. However, in the anterior cortex, a finer, more diffuse pattern of labeling is seen, unlike the distinct banded pattern of mossy fiber rosettes which characterizes the spinocerebellar projection in the normal animal.
authors.affiliation: Department of Anatomy, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107.
authors.forename: L M
authors.initials: LM
authors.lastname: Eisenman
authors.forename: L E
authors.initials: LE
authors.lastname: Arlinghaus
mesh_terms: D000818:Animals; D002531:Cerebellum / Q000166:cytology*; D006735:Horseradish Peroxidase; D007150:Immunohistochemistry; D007278:Injections, Spinal; D051379:Mice; D008818:Mice, Neurologic Mutants / Q000502:physiology*; D009434:Neural Pathways / Q000166:cytology; D013116:Spinal Cord / Q000166:cytology*; D018998:Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; D014909:Wheat Germ Agglutinins
chemical_list: D018998:Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; D014909:Wheat Germ Agglutinins; D006735:Horseradish Peroxidase