title: [Initial results of the anti-HIV-1/2 combined ELISA].
abstract: Between March 30 and July 31, 1989, 117,874 blood donations were tested for anti-HIV-1 and in a combined ELISA for anti-HIV-1/HIV-2 (both Abbott). On each repeat reactive (14 = 0.01% for anti-HIV-1 and 400 = 0.34% for anti-HIV-1/HIV-2), a Western blot (WB) was performed. Two donors, who tested repeatedly reactive in both ELISAs, were confirmed anti-HIV-1 positive by WB. As the specificity of anti-HIV-1/HIV-2 ELISA is considerably lower (99.66%) than of anti-HIV-1 (99.99%), introduction of a different HIV-2 specific ELISA should be discussed to prevent loss of too many blood donations and donors through anti-HIV screening.
authors.affiliation: Blutspendedienst des Bayerischen Roten Kreuzes, München.
authors.forename: U
authors.initials: U
authors.lastname: Bäcker
authors.forename: B
authors.initials: B
authors.lastname: Gathof
authors.forename: J
authors.initials: J
authors.lastname: Eberle
authors.forename: L
authors.initials: L
authors.lastname: Gürtler
mesh_terms: D015492:AIDS Serodiagnosis / Q000379:methods*; D001782:Blood Donors; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods*; D005858:Germany; D015658:HIV Infections / Q000517:prevention & control*; D015528:HIV Seroprevalence / Q000639:trends; D015497:HIV-1 / Q000276:immunology*; D015498:HIV-2 / Q000276:immunology*; D006801:Humans; D012307:Risk Factors
vernacular_title: Erste Ergebnisse des Anti-HIV-1/2, Combi-ELISA.