An identical epitope in Pneumocystis carinii and Toxoplasma gondii causing serological cross reactions.
A monoclonal antibody raised against membrane proteins of Toxoplasma gondii with molecular weights of 35 and 21 kDa also reacts strongly and "specifically" with surface antigens of Pneumocystis carinii with molecular weights of 394.2 and 69 kDa when used in a direct immunofluorescence antibody test, on the one hand, and in a immunoblot after sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE), on the other. Whether or not this observation might have any phylogenetic relevance remains open.
Hassl
A
A
Abteilung für Medizinische Parasitologie, Universität Wien, Vienna, Austria.
Müller
W A
WA
Aspöck
H
H
D000818:Animals; D000946:Antigens, Fungal / Q000032:analysis*; D000953:Antigens, Protozoan / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis; D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology; D003429:Cross Reactions; D004591:Electrophoresis, Polyacrylamide Gel; D000939:Epitopes / Q000032:analysis; D005455:Fluorescent Antibody Technique; D015151:Immunoblotting; D010802:Phylogeny; D011010:Pneumocystis / Q000145:classification / Q000276:immunology*; D014122:Toxoplasma / Q000145:classification / Q000276:immunology*
D000946:Antigens, Fungal; D000953:Antigens, Protozoan; D000954:Antigens, Surface; D000939:Epitopes