Continuous subcutaneous infusion of hyoscine butylbromide reduces secretions in patients with gastrointestinal obstruction.
We describe the use of hyoscine butylbromide as a subcutaneous infusion in 3 patients with inoperable malignant bowel obstruction. An objective reduction of drainage from the gastrointestinal tract was observed with the hyoscine butylbromide infusion (60-120 mg/day). We suggest that this effect can be useful in the palliative treatment of vomiting in inoperable bowel obstruction.
De Conno
F
F
Caraceni
A
A
Zecca
E
E
Spoldi
E
E
Ventafridda
V
V
D000368:Aged; D002086:Butylscopolammonium Bromide / Q000008:administration & dosage* / Q000494:pharmacology; D004322:Drainage; D005260:Female; D005833:Genital Neoplasms, Female / Q000150:complications; D006801:Humans; D007279:Injections, Subcutaneous; D007415:Intestinal Obstruction / Q000209:etiology / Q000628:therapy*; D007419:Intestinal Secretions / Q000187:drug effects*; D007441:Intubation, Gastrointestinal; D008875:Middle Aged; D010166:Palliative Care
D002086:Butylscopolammonium Bromide