title: Expression of tenascin in perifollicular connective tissue: comparison of normal scalp and alopecia areata.
abstract: Tenascin, a recently discovered extracellular matrix protein, was demonstrated in perifollicular connective tissue of normal human scalp using immunohistochemistry. Its localization was different from other well-known extracellular matrix components, like fibronectin, laminin and heparan sulphate proteoglycan. A comparison between alopecia areata and normal scalps did not reveal major qualitative differences, except for an increased expression near heavily infiltrated follicles.
authors.affiliation: Department of Dermatology, University Nijmegen, The Netherlands.
authors.forename: H M
authors.initials: HM
authors.lastname: van Baar
authors.forename: C M
authors.initials: CM
authors.lastname: Perret
authors.forename: I M
authors.initials: IM
authors.lastname: van Vlijmen-Willems
authors.forename: J P
authors.initials: JP
authors.lastname: Cleutjens
authors.forename: E J
authors.initials: EJ
authors.lastname: Mackie
authors.forename: R
authors.initials: R
authors.lastname: Happle
authors.forename: J
authors.initials: J
authors.lastname: Schalkwijk
mesh_terms: D000506:Alopecia Areata / Q000378:metabolism* / Q000473:pathology; D015816:Cell Adhesion Molecules, Neuronal / Q000378:metabolism*; D003238:Connective Tissue / Q000378:metabolism*; D016326:Extracellular Matrix Proteins / Q000378:metabolism*; D005353:Fibronectins / Q000378:metabolism; D006197:Hair / Q000166:cytology / Q000378:metabolism* / Q000473:pathology; D006497:Heparan Sulfate / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D007797:Laminin / Q000378:metabolism; D012535:Scalp / Q000166:cytology / Q000378:metabolism*; D019063:Tenascin
chemical_list: D015816:Cell Adhesion Molecules, Neuronal; D016326:Extracellular Matrix Proteins; D005353:Fibronectins; D006497:Heparan Sulfate; D007797:Laminin; D019063:Tenascin