A case of gallbladder cancer producing granulocyte-colony-stimulating factor.
A patient with pleomorphic giant cell carcinoma of the gallbladder also had mild neutrophilia, and this tumor was found to be human granulocyte colony-stimulating factor (G-CSF)-positive on immunohistochemical staining. CSF activity in urine and serum was not examined, but leukocytosis disappeared immediately after cholecystectomy. These findings suggest that this was a G-CSF-producing tumor.
Takeda
T
T
Department of Internal Medicine, Sano Hospital, Kobe, Japan.
Ichiyanagi
A
A
Sano
K
K
Yoshida
J
J
Tsutsumi
Y
Y
Miyaji
T
T
D000368:Aged; D002277:Carcinoma / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology; D005260:Female; D005704:Gallbladder / Q000473:pathology; D005706:Gallbladder Neoplasms / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology; D016179:Granulocyte Colony-Stimulating Factor / Q000378:metabolism*; D006801:Humans
D016179:Granulocyte Colony-Stimulating Factor