[The dynamics of the blood level of phosphatidylinositol in patients with myocardial infarction].
Phospholipids, particularly inositol-containing ones, that serve as secondary messengers and bioregulators of fundamental biochemical processes, essentially contribute to the origination of cardiovascular diseases. These compounds are highly labile and the data on their levels in the blood and its components in various cardiovascular conditions are contradictory. This may be explained by the fact that phosphatidylinositol levels change immediately after blood collection. Therefore the authors found it interesting to investigate the time course of this phospholipid levels, that may to a certain measure reflect the pattern of the metabolic disorders present in this case. They suggest a method of multiple measurements of phosphatidylinositol levels, carried out in short intervals, this yielding additional data on the function of biologic membranes, that may be useful in the diagnosis of coronary disease and assessment of the efficacy of treatment of this condition.
Lopina
N P
NP
Bykovskaia
N G
NG
Kargapolov
A V
AV
Anikin
V V
VV
Iastrebov
G N
GN
D000328:Adult; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood*; D010716:Phosphatidylinositols / Q000097:blood*
D010716:Phosphatidylinositols
Dinamika soderzhaniia v krovi fosfatidilinozita u bol'nykh infarktom miokarda.