title: The thermogenic role of exercise in the treatment of morbid obesity: a critical evaluation.
abstract: Exercise induces negative energy balance either directly or by enhancing meal thermogenesis, increasing resting metabolic rate, and/or decreasing food intake. A quantitative evaluation of these effects in programs of weight control led to the following conclusions: 1) energy cost of exercise per se is minimal, 2) effects on thermic of food are negligible, and 3) exercise training may be advantageous in conjunction with low-calorie diet programs because it helps to maintain resting metabolic rate and fat-free mass. However, exercise may not prevent, and may even accentuate, the fall in metabolic rate in programs of severe calorie restriction, thus hampering weight reduction. Overall, exercise should not be envisioned as a sole agent to induce negative energy balance, but it is an essential element in comprehensive programs for morbidly obese patients due to its effects on lipids, carbohydrate metabolism, and cardiovascular system.
authors.affiliation: Department of Medicine, University of Vermont, Burlington 05405.
authors.forename: J
authors.initials: J
authors.lastname: Calles-Escandón
authors.forename: E S
authors.initials: ES
authors.lastname: Horton
mesh_terms: D004734:Energy Metabolism; D015444:Exercise; D006801:Humans; D009767:Obesity, Morbid / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy*