Impaired bactericidal activity of serum of a child suffering from focal proliferative glomerulonephritis.
The serum of a child with focal proliferative glomerulonephritis was found to exhibit a weaker bactericidal activity against Pseudomonas aeruginosa, Salmonella typhimurium, Salmonella enteritidis and Escherichia coli strains as compared with sera of the child's parents. The child's serum showed a low haemolytical activity of complement as well as a low C3 concentration. The authors believe that the abnormal complement concentration could cause the impaired bactericidal activity of the patient serum.
Jankowski
S
S
Department of Microbiology, Academy of Medicine, Wrocław, Poland.
Galar
A
A
Grzybek-Hryncewicz
K
K
Walczuk
M
M
D001770:Blood Bactericidal Activity; D002648:Child; D003165:Complement System Proteins / Q000276:immunology; D005260:Female; D005923:Glomerulosclerosis, Focal Segmental / Q000276:immunology*; D006801:Humans
D003165:Complement System Proteins