Staphylococcal L-asparaginase: antilymphoma and immunosuppressive action.
Staphylococcal L-asparaginase inhibits blastic transformation of human lymphocytes and growth of mice leukemia lymphoblasts L5178Y-R. The enzyme is removed from blood stream of DBA/2 mice very rapidly.
Sobiś
M
M
Department of Pharmaceutical Microbiology, Medical University, Lódź, Poland.
Mikucki
J
J
Lisiecki
P
P
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D001215:Asparaginase / Q000502:physiology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007940:Leukemia L5178 / Q000188:drug therapy / Q000201:enzymology; D008223:Lymphoma / Q000188:drug therapy* / Q000201:enzymology; D051379:Mice; D008811:Mice, Inbred DBA; D013211:Staphylococcus aureus / Q000201:enzymology*; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D007166:Immunosuppressive Agents; D001215:Asparaginase