[Lipid peroxidation in vasopressin-induced pulmonary edema and hyperbaric oxygenation therapy].
Experiments in 150 albino rats have revealed that hyperbaric oxygenation (303.98 kPa) causes no decrease in pulmonary tissue hyperhydration and its blood filling induced by pituitrin administration. Hyperbaric oxygen therapy enhances pulmonary tissue peroxidation of lipids, without modifying them in blood. Application of lipid peroxidation inhibitors to prevention of pulmonary edema fails to affect pulmonary hydration and blood filling, which does not rule out the possibility of using them as protective agents against the toxic effects of oxygen in myocardial infarction which may be complicated by acute pulmonary edema.
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D000818:Animals; D000975:Antioxidants; D000075202:Contraindications; D004195:Disease Models, Animal; D006931:Hyperbaric Oxygenation; D007275:Injections, Intravenous; D015227:Lipid Peroxidation / Q000187:drug effects / Q000502:physiology*; D010909:Pituitary Hormones, Posterior / Q000008:administration & dosage / Q000037:antagonists & inhibitors; D011654:Pulmonary Edema / Q000139:chemically induced / Q000378:metabolism* / Q000628:therapy; D051381:Rats; D014508:Urea / Q000627:therapeutic use; D014810:Vitamin E / Q000627:therapeutic use
D000975:Antioxidants; D010909:Pituitary Hormones, Posterior; D014810:Vitamin E; D014508:Urea
Perekisnoe okislenie lipidov pri vazopressinovom oteke legkikh i giperoksibaroterapii.