title: Neovascularisation of the meniscus with angiogenin. An experimental study in rabbits.
abstract: Angiogenin, a potent blood vessel inducing protein, was implanted into experimentally injured menisci of 75 New Zealand white rabbits. Localised neovascularisation occurred in 52% of the angiogenin-treated animals, and in 9% of the controls. Neovascularisation induced by angiogenin may enhance healing of injuries within the poorly vascularised meniscal fibrocartilage, and improve the results of meniscal repair.
authors.affiliation: Harvard Medical School, Boston, Massachusetts 02115.
authors.forename: T V
authors.initials: TV
authors.lastname: King
authors.forename: B L
authors.initials: BL
authors.lastname: Vallee
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D008592:Menisci, Tibial / Q000098:blood supply / Q000187:drug effects* / Q000473:pathology; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging* / Q000473:pathology; D011506:Proteins / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D011817:Rabbits; D011859:Radiography; D012259:Ribonuclease, Pancreatic; D014945:Wound Healing / Q000187:drug effects
chemical_list: D011506:Proteins; C046366:angiogenin; D012259:Ribonuclease, Pancreatic