title: The thyroid nodule: diagnostic strategy.
abstract: This paper comments on the principal techniques (nuclear imaging echography and needle aspiration) and the most widely used protocols available for preoperative selection of thyroid nodule patients. Successively, the authors report the principles to define a new appropriate protocol based on needle aspiration and hormone assays and evaluate their experience with this new simple protocol. Long term clinical practices shows that surgical excision can be avoided for more than 90% of the nodule patients and that thyroid scintigraphy can be avoided for most of these patients, without appreciable disadvantage.
authors.affiliation: Nuclear Medicine Service, University of Pisa, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Carpi
authors.forename: M G
authors.initials: MG
authors.lastname: Toni
authors.forename: G
authors.initials: G
authors.lastname: Di Coscio
authors.forename: A
authors.initials: A
authors.lastname: Nicolini
authors.forename: A
authors.initials: A
authors.lastname: Sagripanti
mesh_terms: D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000379:methods; D006801:Humans; D006980:Hyperthyroidism / Q000175:diagnosis / Q000188:drug therapy; D008875:Middle Aged; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000601:surgery; D016606:Thyroid Nodule / Q000175:diagnosis* / Q000000981:diagnostic imaging; D013973:Thyrotropin-Releasing Hormone / Q000032:analysis; D013974:Thyroxine / Q000627:therapeutic use; D014463:Ultrasonography
chemical_list: D013973:Thyrotropin-Releasing Hormone; D013974:Thyroxine