Origin of cuneate projections to the anterior and posterior lobes of the rat cerebellum.
The present study was carried out to analyze the topography of projections from external cuneate nucleus to the anterior and posterior lobes of the cerebellum and to investigate whether projections to the two lobes come from different cuneocerebellar neurons or from branching axons of the same cells. We used retrograde double-labeling techniques to estimate the incidence of cuneocerebellar neurons projecting to both anterior and posterior lobes via axon collaterals. Cells sending their axons to the lobus anterior were about twice the number of those projecting to the posterior lobe. The double-labeled cells were about 1/7 of all labeled neurons and were located mainly in the more lateral half of the nucleus. Therefore, the two lobes of the cerebellum are likely to receive common information from these cells, but different information from the separate populations of cuneocerebellar neurons that project only to one lobe or the other.
Berretta
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Institute of Human Physiology, University of Catania, Italy.
Perciavalle
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Poppele
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D000818:Animals; D001369:Axons / Q000502:physiology; D002531:Cerebellum / Q000166:cytology* / Q000502:physiology; D003102:Colloids; D005456:Fluorescent Dyes; D006046:Gold; D006735:Horseradish Peroxidase; D008297:Male; D008526:Medulla Oblongata / Q000166:cytology* / Q000502:physiology; D009434:Neural Pathways / Q000166:cytology* / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D013266:Stilbamidines; D018998:Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; D014909:Wheat Germ Agglutinins
C049774:2-hydroxy-4,4'-diamidinostilbene, methanesulfonate salt; D003102:Colloids; D005456:Fluorescent Dyes; D013266:Stilbamidines; D018998:Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate; D014909:Wheat Germ Agglutinins; D006046:Gold; D006735:Horseradish Peroxidase