[Relapsing polychondritis in a patient with myelodysplastic syndrome].
Relapsing polychondritis is a rare disorder of uncertain origin characterized by recurrent inflammation of cartilage. A case of myelodysplastic syndrome (MDS) associated with relapsing polychondritis is reported. A 60-year-old man who had been diagnosed as MDS was admitted because of pain and swelling in the bilateral preauricular regions and cheek. A diagnosis of relapsing polychondritis was made by coexistence of auricular chondritis, arthropathy, ocular inflammation and audio-vestibular disturbance. He also developed ocular palsies and optic neuritis. He was treated with prednisolone, azathioprine, dapsone, and then with steroid pulse therapy. Moreover, plasmapheresis and high dose gamma-globulin therapy were undertaken. However, all these treatments were unsuccessful and he died of respiratory failure.
Tanaka
K
K
First Department of Internal Medicine, Kurume University School of Medicine.
Nakamura
E
E
Naitoh
K
K
Utsunomiya
I
I
Matsuo
K
K
Osabe
S
S
Honda
J
J
Yoshida
K
K
Egami
K
K
Natori
H
H
D001379:Azathioprine / Q000008:administration & dosage; D003622:Dapsone / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000150:complications* / Q000628:therapy; D009902:Optic Neuritis / Q000209:etiology; D010956:Plasmapheresis; D011081:Polychondritis, Relapsing / Q000209:etiology* / Q000628:therapy; D011239:Prednisolone / Q000008:administration & dosage; D005719:gamma-Globulins / Q000008:administration & dosage
D005719:gamma-Globulins; D003622:Dapsone; D011239:Prednisolone; D001379:Azathioprine