Receptors coupled to ionic channels: the glutamate receptor family.
Glutamate-gated ion channels belong to a complex family of receptors containing several pharmacological subtypes. They are thought to be essential for the acquisition of associative memory and for activity-dependent synaptogenesis, and have been implicated in several central nervous system diseases. Within the past year, molecular cloning of the first glutamate receptor channel and several related subunits has opened new approaches for understanding the basis of these important phenomena.
Gasic
G P
GP
Molecular Neurobiology Laboratory, Howard Hughes Medical Institute, Salk Institute, La Jolla, California 92307.
Heinemann
S
S
D000818:Animals; D006801:Humans; D007473:Ion Channels / Q000502:physiology*; D017470:Receptors, Glutamate; D017981:Receptors, Neurotransmitter / Q000502:physiology*
D007473:Ion Channels; D017470:Receptors, Glutamate; D017981:Receptors, Neurotransmitter