title: Immunohistochemical localization of the alpha 1, alpha 2 and alpha 3 subunit of the GABAA receptor in the rat brain.
abstract: The immunohistochemical distribution of the alpha 1, alpha 2 and alpha 3 subunit of the gamma-aminobutyric acid-A (GABAA) receptor was investigated in the rat brain using affinity-purified antibodies against unique parts of the amino acid sequence of the respective subunits. The distribution of the 3 subunits differed markedly from each other indicating heterogeneity of the GABAA-receptor composition in different brain regions and at various receptive compartments (dendrites or somata) of neuronal cells.
authors.affiliation: Research Unit for Experimental Neuropathology, Austrian Academy of Sciences, Vienna.
authors.forename: F
authors.initials: F
authors.lastname: Zimprich
authors.forename: J
authors.initials: J
authors.lastname: Zezula
authors.forename: W
authors.initials: W
authors.lastname: Sieghart
authors.forename: H
authors.initials: H
authors.lastname: Lassmann
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism*; D007150:Immunohistochemistry; D051381:Rats; D011919:Rats, Inbred Strains; D011963:Receptors, GABA-A / Q000378:metabolism*; D013194:Staining and Labeling; D014018:Tissue Distribution
chemical_list: D011963:Receptors, GABA-A