[Results of treatment of habitual abortion by immune stimulation with partner and/or foreign donor lymphocytes].
47 couples with repeated spontaneous first trimester abortions were referred for immunotherapy with lymphocytes from spouse and/or unrelated donor towards stimulation of blocking antibody, protecting the next pregnancy. 40 couples were treated, 38% did not yet conceive again. 69% of the 29 observed pregnancies were successful, as were 3 among the 7 untreated women. A prospective, controlled trial is necessary to determine the value of active immunotherapy recurrent spontaneous first trimester abortion.
Diekamp
U
U
Bluttransfusionsdienst, ZKH St.-Jürgen-Strasse, Bremen.
D000026:Abortion, Habitual / Q000276:immunology / Q000628:therapy*; D000328:Adult; D001666:Binding Sites, Antibody / Q000276:immunology; D001667:Binding, Competitive / Q000276:immunology; D005260:Female; D006801:Humans; D007114:Immunization / Q000379:methods*; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D011247:Pregnancy
Ergebnisse der Behandlung von habituellem Abort durch Immunstimulation mit Partner- und/oder Fremdspenderlymphozyten.