title: Incessant ectopic atrial tachycardia and sudden death.
abstract: A patient with refractory and incessant ectopic atrial tachycardia (IEAT) is reported in whom it was possible to document, during ECG (Holter) the occurrence of aborted sudden death by spontaneous ventricular fibrillation (VF). Following the second of two attempts at surgical ablation of the origin of the IEAT, the patient has been asymptomatic without antiarrhythmic drugs and in sustained sinus rhythm for 24 months. Although we cannot exclude the residual action of amiodarone and flecainide (proarrhythmia) or the residual peripartum cardiomyopathy it is probable that the observed VF was a true complication of a cardiomyopathy induced by a chronically increased heart rate (HR). Although unclear, this VF might be considered as a form of adrenergic-dependent long QT syndrome due to early afterdepolarization in the presence of predisposing myocardial conditions.
authors.affiliation: Sao Paulo University Medical School Heart Institute (INCOR), Sao Paulo, Brazil.
authors.forename: E
authors.initials: E
authors.lastname: Sosa
authors.forename: M B
authors.initials: MB
authors.lastname: Marcial
authors.forename: M
authors.initials: M
authors.lastname: Scanavacca
authors.forename: G
authors.initials: G
authors.lastname: Bellotti
authors.forename: F
authors.initials: F
authors.lastname: Pileggi
mesh_terms: D000328:Adult; D016280:Atrial Function, Right / Q000502:physiology; D003645:Death, Sudden; D004562:Electrocardiography; D005260:Female; D006323:Heart Arrest / Q000503:physiopathology; D006801:Humans; D013612:Tachycardia, Ectopic Atrial / Q000503:physiopathology; D014693:Ventricular Fibrillation / Q000503:physiopathology