[Comparative study of immunosuppressive properties of pregnancy- associated protein A, alpha 2-glucoprotein and alpha 2-macroglobulin].
Effects of high-molecular proteinase inhibitors on spontaneous and mitogen-induced lymphocyte proliferation were examined in males and pregnant and non-pregnant females. All three proteins, A protein, alpha 2-glycoprotein, and alpha 2-macroglobulin were found to be potent immunosuppressors and their activity was determined by the stage of pregnancy, the dose and mode of mitogenic lymphocyte stimulation.
Mal'tseva
N V
NV
Gorin
V S
VS
Zhabin
S G
SG
Zorin
N A
NA
D003470:Culture Media; D005260:Female; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology*; D066298:In Vitro Techniques; D008213:Lymphocyte Activation / Q000187:drug effects / Q000276:immunology; D008934:Mitogens / Q000494:pharmacology; D009000:Monocytes / Q000276:immunology*; D011247:Pregnancy / Q000276:immunology*; D011257:Pregnancy Proteins / Q000276:immunology*; D011266:Pregnancy-Associated Plasma Protein-A / Q000276:immunology*; D000511:alpha-Macroglobulins / Q000276:immunology*
D003470:Culture Media; D008934:Mitogens; D011257:Pregnancy Proteins; D000511:alpha-Macroglobulins; D011266:Pregnancy-Associated Plasma Protein-A
Sravnitel'noe izuchenie immunosupressivnykh svoĭstv assotsirovannykh s beremennost'iu proteina A i alpha 2-glikoproteina, a takzhe alpha 2-makroglobulina.