[The effect of taurine on the electrically controlled ion channels of the somatic membrane of pond snail neurons].
Isolated and internally dialysed neurons from the molluscs Lymnaea stagnalis were investigated under voltage-clamp conditions. The increasing of taurin concentration (from 1.10(-8) to 1.10(-2) mol/l) reduced the calcium inward--and delayed potassium outward currents, and exerted no effect on the fast potassium outward current. Sodium inward current was increased by taurin concentrations 1.10(-8)-1.10(-4) mol/l, and reduced by 1.10(-3)-1.10(-2) mol/l. Membrane leakage currents were reduced by small taurin concentrations and increased by large concentrations.
Vislobokov
A I
AI
Mantsev
V V
VV
Kopylov
A G
AG
Gurevich
V S
VS
D000818:Animals; D002462:Cell Membrane / Q000187:drug effects / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D066298:In Vitro Techniques; D007473:Ion Channels / Q000187:drug effects* / Q000502:physiology; D008195:Lymnaea / Q000187:drug effects* / Q000502:physiology; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D013654:Taurine / Q000494:pharmacology*
D007473:Ion Channels; D013654:Taurine
Vliianie taurina na élektroupravliaemye ionnye kanaly somaticheskoĭ membrany neĭronov prudovika.