title: Hematologic data in 825 cases of beta-thalassemia trait in Spain.
abstract: We present the hematologic data of 825 cases of beta-thalassemia trait (687 cases of beta-thalassemia trait and 138 cases of delta beta-thalassemia trait). There were no significant differences between the red cell indices of the patients with beta and delta beta-thalassemia trait. In patients with beta-thalassemia trait, MCV was significantly reduced in 97% of the males and 99% of the females. All the patients with delta beta-thalassemia trait showed low MCV values. Red cell morphology was altered in the vast majority of cases, with basophilic stippling in 96% of the patients. Most patients came from provinces with the highest incidence of malaria in the past.
authors.affiliation: Servicio de Hematologia, Hospital Universitario San Carlos, Universidad Complutense de Madrid, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Calero
authors.forename: A
authors.initials: A
authors.lastname: Villegas
authors.forename: A
authors.initials: A
authors.lastname: Porres
authors.forename: F
authors.initials: F
authors.lastname: Valverde
authors.forename: E
authors.initials: E
authors.lastname: del Potro
authors.forename: P
authors.initials: P
authors.lastname: Sánchez
authors.forename: J M
authors.initials: JM
authors.lastname: Luque
authors.forename: D
authors.initials: D
authors.lastname: Espinós
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D005319:Fetal Hemoglobin / Q000378:metabolism; D006443:Hemoglobin A2 / Q000378:metabolism; D006579:Heterozygote; D006801:Humans; D008288:Malaria / Q000453:epidemiology / Q000235:genetics*; D008297:Male; D013030:Spain / Q000453:epidemiology; D013789:Thalassemia / Q000097:blood* / Q000235:genetics
chemical_list: D006443:Hemoglobin A2; D005319:Fetal Hemoglobin