title: [Production of leukocyte-poor thrombocyte concentrates: results with a new kind of filter system].
abstract: A newly developed filter-system (Sepacell PL) for the removal of leukocytes from single donor platelet concentrates was tested. It removes contaminating leukocytes by 99.9%, the platelet loss was calculated as less than 1%. Platelet ultrastructure and function do not seem to be altered by the filtration. Therefore, the tested filter system seems to be a suitable device for leukocyte depletion of single donor platelet concentrates. Further clinical studies, however, are necessary to prove the efficiency of the filter system in preventing alloimmunization in vivo.
authors.affiliation: Transfusionszentrum (Med. Klinik III), Klinikum Grosshadern, Universität München.
authors.forename: M
authors.initials: M
authors.lastname: Böck
authors.forename: C
authors.initials: C
authors.lastname: Salat
authors.forename: L
authors.initials: L
authors.lastname: Greither
authors.forename: M U
authors.initials: MU
authors.lastname: Heim
authors.forename: R
authors.initials: R
authors.lastname: Weindler
authors.forename: A
authors.initials: A
authors.lastname: Bilas
authors.forename: W
authors.initials: W
authors.lastname: Mempel
mesh_terms: D001803:Blood Transfusion / Q000295:instrumentation*; D002469:Cell Separation / Q000295:instrumentation*; D006801:Humans; D007958:Leukocyte Count; D010974:Platelet Aggregation / Q000502:physiology; D010976:Platelet Count; D017713:Platelet Transfusion; D010983:Plateletpheresis / Q000295:instrumentation*
vernacular_title: Herstellung leukozytenarmer Thrombozytenkonzentrate: Ergebnisse mit einem neuartigen Filtersystem.