Usefulness of a near-total fine-needle aspiration biopsy retrieval method: a study of its use in 85 consecutive patients.
Fine-needle aspiration biopsy may provide miniscule material for diagnosis. A method was devised to ensure optimal retrieval of the specimen. If performed in the manner described, at least four to five different samples from each case may be obtained. This includes a smear stained with the Papanicolaou and hematoxylin and eosin methods, a cell block preparation, and at least two cytocentrifuge specimens. In 85 cases in which the method was applied and subsequently analyzed, we found the cell block and Papanicolaou-stained smears to be most effective for diagnosis, whereas the cytocentrifuge method was much less effective. The sensitivity and specificity were 93% and 100%, respectively.
Dekker
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Department of Pathology, School of Medicine, University of Pittsburgh, PA.
Reyna
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Fuhrman
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D000368:Aged; D001707:Biopsy, Needle / Q000379:methods*; D002277:Carcinoma / Q000473:pathology; D002498:Centrifugation; D005260:Female; D006652:Histological Techniques; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000175:diagnosis* / Q000473:pathology; D012680:Sensitivity and Specificity; D013194:Staining and Labeling