title: Advanced nasopharyngeal carcinoma: radiation treatment and chemotherapy approaches, and life table survival results.
abstract: Induction combination chemotherapy and radiotherapy was tried in 50 patients with T3-T4 nasopharyngeal carcinoma. The results were compared to another matching group of 50 patients given radical radiotherapy. The study showed preliminary improvement of local control rates of the tumour in patients treated by combination chemotherapy with radiation. The actuarial method of survival computation was applied, also the variance and standard error of the four years survival rates for both treatment groups was computed. Comparison of the survival rates showed no significant difference between group I (received combined chemo and radiotherapy) and group II (Radiation therapy) throughout the observation period.
authors.affiliation: Radiotherapy Unit, Faculty of Medicine, Alexandria University.
authors.forename: N
authors.initials: N
authors.lastname: el-Ghamry
authors.forename: A
authors.initials: A
authors.lastname: el-Ghamry
authors.forename: S A
authors.initials: SA
authors.lastname: Mokhtar
authors.forename: A
authors.initials: A
authors.lastname: Omran
authors.forename: M
authors.initials: M
authors.lastname: Zewil
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000532:radiotherapy; D002648:Child; D002945:Cisplatin / Q000008:administration & dosage; D003037:Cobalt Radioisotopes; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy; D011867:Radioisotope Teletherapy; D016019:Survival Analysis
chemical_list: D003037:Cobalt Radioisotopes; D001761:Bleomycin; D002945:Cisplatin; D008727:Methotrexate