title: Light-induced, GTP-binding protein mediated membrane currents of Xenopus oocytes injected with rhodopsin of cephalopods.
abstract: Xenopus oocytes that were injected with rhabdomeric membranes of squid and octopus photoreceptors acquired light sensitivity. The injected oocytes showed a light-induced current having characteristics similar to other G-protein-mediated Cl- currents induced by the activation of other membrane receptors. Pretreatment of the oocytes with pertussis toxin before the injection suppressed the generation of the light-induced current, indicating an ability of cephalopod rhodopsin to cross-react with an endogenous G-protein of Xenopus oocytes.
authors.affiliation: Department of Physiology, School of Medicine, Kobe University, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Ando
authors.forename: M
authors.initials: M
authors.lastname: Seidou
authors.forename: Y
authors.initials: Y
authors.lastname: Kito
mesh_terms: D000818:Animals; D002712:Chlorides / Q000502:physiology; D003429:Cross Reactions; D049832:Decapodiformes; D005260:Female; D019204:GTP-Binding Proteins / Q000502:physiology*; D007473:Ion Channels / Q000502:physiology; D008564:Membrane Potentials / Q000187:drug effects; D049831:Octopodiformes; D009865:Oocytes / Q000502:physiology*; D010775:Photic Stimulation; D012243:Rhodopsin / Q000502:physiology*; D013997:Time Factors; D014982:Xenopus laevis
chemical_list: D002712:Chlorides; D007473:Ion Channels; D012243:Rhodopsin; D019204:GTP-Binding Proteins