Tentative assignment of gene for oto-palato-digital syndrome to distal Xq (Xq26-q28).
Detailed physical mapping of oto-palato-digital (OPD) syndrome gene on the X-chromosome was attempted on a family of 3 generations with 2 affected men. Although the result remains statistically non-significant, it indicates that the OPD-I gene might be located on the distal Xq.
Hoar
D I
DI
Department of Pediatrics, University of Calgary/Alberta Children's Hospital Research Center, Canada.
Field
L L
LL
Beards
F
F
Hoganson
G
G
Rollnick
B
B
Hoo
J J
JJ
D002874:Chromosome Mapping; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D008126:Lod Score; D008297:Male; D010375:Pedigree; D011995:Recombination, Genetic; D012729:Sex Chromosome Aberrations / Q000235:genetics*; D013577:Syndrome; D014960:X Chromosome