title: Aggregation of human granulocytes by Staphylococcus aureus lipase.
abstract: The effects of purified extracellular lipase from Staphylococcus aureus on human granulocytes were studied in vitro with a turbidimetric technique. Within the concentration range 0.6-4.4 micrograms/ml, lipase caused monophasic aggregation accompanied by the release of lactoferrin; the corresponding concentrations of the solvent in which it was suspended, Triton X100, had no effect. Lipase-induced aggregation did not occur in the presence of autologous plasma.
authors.affiliation: Department of Infectious Diseases, University Hospital of Lund, Sweden.
authors.forename: J
authors.initials: J
authors.lastname: Rollof
authors.forename: E
authors.initials: E
authors.lastname: Vinge
authors.forename: P
authors.initials: P
authors.lastname: Nilsson-Ehle
authors.forename: J H
authors.initials: JH
authors.lastname: Braconier
mesh_terms: D002449:Cell Aggregation / Q000502:physiology*; D006098:Granulocytes / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D007781:Lactoferrin / Q000032:analysis; D008049:Lipase / Q000378:metabolism*; D017830:Octoxynol; D011092:Polyethylene Glycols; D013211:Staphylococcus aureus / Q000201:enzymology*; D013696:Temperature
chemical_list: D011092:Polyethylene Glycols; D017830:Octoxynol; D008049:Lipase; D007781:Lactoferrin