Congenital miliary tuberculosis.
A case of a premature baby who had the classical problems associated with congenital tuberculosis and presented a difficult diagnostic problem is described. Diagnosis was ultimately confirmed by liver biopsy. Treatment was initially with isoniazid alone, followed 2 weeks later by isoniazid and rifampicin. Isoniazid was replaced by ethambutol when an isoniazid-resistant culture was obtained. The baby responded extremely well to therapy and, at 2-year follow-up, was growing satisfactorily without any sequelae. To my knowledge, this is the first case of congenital tuberculosis with a miliary spread to be seen, treated and followed up in the developing world, where tuberculosis is prevalent.
Airede
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Department of Paediatrics, Faculty of Medical Sciences, University of Jos, Nigeria.
D000995:Antitubercular Agents / Q000008:administration & dosage; D001706:Biopsy; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008099:Liver / Q000473:pathology; D008297:Male; D014391:Tuberculosis, Miliary / Q000151:congenital* / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
D000995:Antitubercular Agents