Cold agglutinin disease after chicken pox. An uncommon complication of a common disease.
Chicken pox, although common, is rarely associated with autoimmune hemolytic anemia. Reported here is the case of an 8-year-old boy who was found to have cold agglutinin disease and severe anemia several days after he contracted chicken pox. The cold agglutinin appeared to be a polyclonal immunoglobulin M antibody with anti-Pr specificity. To our knowledge, this is the fifth reported case of autoimmune hemolytic anemia and the second reported case of cold agglutinin disease with anti-Pr specificity to be associated with chicken pox.
Friedman
H D
HD
Department of Pathology, State University of New York-Health Science Center, Syracuse 13210.
Dracker
R A
RA
D000744:Anemia, Hemolytic, Autoimmune / Q000097:blood / Q000209:etiology* / Q000628:therapy; D002644:Chickenpox / Q000097:blood / Q000150:complications*; D002648:Child; D006801:Humans; D008297:Male