title: Cefminox sodium penetration into prostatic tissue with and without inflammation.
abstract: The concentrations of cefminox sodium (CMNX) in serum and prostatic tissue were determined in 36 cases of prostatic hyperplasia with and without inflammation. Mean ratios of CMNX in tissue over concentration in serum were 0.11 +/- 0.07 for patients with inflammation and 0.09 +/- 0.06 for those without inflammation. There was no significant difference between the two groups. These data suggest that CMNX penetration into prostatic tissue is not influenced by the presence of inflammation.
authors.affiliation: Department of Urology, Saiseikai Fukushima General Hospital, Japan.
authors.forename: I
authors.initials: I
authors.lastname: Sasagawa
authors.forename: O
authors.initials: O
authors.lastname: Yamaguchi
authors.forename: Y
authors.initials: Y
authors.lastname: Shiraiwa
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002513:Cephamycins / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000627:therapeutic use; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000378:metabolism*; D011470:Prostatic Hyperplasia / Q000150:complications / Q000188:drug therapy / Q000378:metabolism*; D011472:Prostatitis / Q000150:complications / Q000188:drug therapy / Q000378:metabolism*
chemical_list: D002513:Cephamycins; C046079:cefminox