The activity of neutrophil myeloperoxidase in patients with Hodgkin's disease.
Neutrophil myeloperoxidase activity has been studied in twenty one patients diagnosed with Hodgkin's disease. The presented data indicate no differences in total MPO activity, whereas we observed some differences in the percentage of granulocytes with different degree of scores. Changes in the intensity of reaction may indicate the possibility of exocytosis as a mechanism releasing MPO from the cell to the surrounding area. In peripheral, circulating neutrophils, such a phenomenon seems to be of no avail and may disorganise anti-cancer defence.
Dabrowska
M
M
Department of Laboratory Clinical Diagnostics, Medical School, Białystok, Poland.
Kemona
H
H
Prokopowicz
J
J
Dabrowski
A
A
Kiluk
S
S
D000328:Adult; D000368:Aged; D005260:Female; D006098:Granulocytes / Q000201:enzymology / Q000473:pathology; D006689:Hodgkin Disease / Q000097:blood / Q000201:enzymology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D009504:Neutrophils / Q000201:enzymology*; D009195:Peroxidase / Q000097:blood*; D012016:Reference Values
D009195:Peroxidase