title: [Serum trophoblastic beta 1-glycoprotein and alpha fetoprotein levels in physiological pregnancy].
abstract: Measurements of maternal blood serum trophoblastic beta 1-glycoprotein and alpha-fetoprotein, carried out over the course of normal pregnancy, have demonstrated a progressive increase of trophoblastic beta 1-glycoprotein up to the 36th week, though its level somewhat reduced during the 28th and 32nd weeks. After week 39 the level of this protein in maternal blood serum progressively lowered. alpha-Fetoprotein level was increasing over the course of pregnancy as long as up to the 32nd-34th weeks, then lowering the rest of the term up to delivery. These data permit a conclusion that the time course of the afore-said specific protein concentrations in pregnancy sufficiently well reflects the processes of fetoplacental system establishment and functioning, this permitting the use of these protein measurements in monitoring the course of gestation.
authors.forename: N M
authors.initials: NM
authors.lastname: Pobedinskiĭ
authors.forename: N I
authors.initials: NI
authors.lastname: Razmakhnina
authors.forename: L S
authors.initials: LS
authors.lastname: Aleksandrov
authors.forename: Iu Iu
authors.initials: IuIu
authors.lastname: Vengerov
authors.forename: T A
authors.initials: TA
authors.lastname: Starovoĭtova
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D011247:Pregnancy / Q000097:blood*; D011261:Pregnancy Trimester, First; D011263:Pregnancy Trimester, Third; D011268:Pregnancy-Specific beta 1-Glycoproteins / Q000032:analysis* / Q000096:biosynthesis; D014327:Trophoblasts / Q000378:metabolism*; D000509:alpha-Fetoproteins / Q000032:analysis* / Q000096:biosynthesis
chemical_list: D011268:Pregnancy-Specific beta 1-Glycoproteins; D000509:alpha-Fetoproteins
vernacular_title: Soderzhanie trofoblasticheskogo beta1-glicoproteina i alpha- fetoproteina v syvorotke krovi pri fiziologicheski protekaiushcheĭ beremennosti.