[Glucocorticoid function of the adrenal cortex in patients with myocardial infarction: study of elimination of exogenous cortisol].
The paper yields the results of the study into the elimination of exogenous cortisol from the blood bed in 26 patients with myocardial infarction. It is concluded that the nature of cortisol elimination may reflect the natural history and prediction of myocardial infarction. In terms of the body tissue demand, two type of elimination are identified: retarded (a favorable type) and accelerated (an unfavorable type). The data on the nature of cortisol elimination may serve as an indication for glucocorticoid therapy. The baseline cortisol concentrations fail to reflect the nature of glucocorticoid metabolism in patients with myocardial infarction.
Kuimov
A D
AD
Iakobson
M G
MG
Shershnev
V N
VN
Iakobson
G S
GS
D000302:Adrenal Cortex / Q000378:metabolism*; D000328:Adult; D000368:Aged; D005260:Female; D005938:Glucocorticoids / Q000493:pharmacokinetics; D006801:Humans; D006854:Hydrocortisone / Q000378:metabolism / Q000493:pharmacokinetics*; D008297:Male; D008657:Metabolic Clearance Rate / Q000502:physiology; D008875:Middle Aged; D009203:Myocardial Infarction / Q000378:metabolism*; D013997:Time Factors
D005938:Glucocorticoids; D006854:Hydrocortisone
Gliukokortikoidnaia funktsiia kory nadpochechnikov u bol'nykh infarktom miokarda: issledovanie éliminatsii ékzogennogo kortizola.