[Increased expression of the OKM5 antigen in blood monocytes in vitiligo].
In 25 patients suffering from vitiligo, we determined the T-cell profile (OKT3, 4 and 8; anti-Leu7) as well as the peripheral monocytes (OKM5) by means of monoclonal antibodies. Comparing the patients with a control group (n = 8), we found no differences regarding the T-cell count, whereas the expression of OKM5 antigens on peripheral monocytes was significantly elevated in patients with vitiligo.
Baumer
F E
FE
Zentrum der Dermatologie und Venerologie, J.W. Goethe-Universität, Frankfurt am Main.
Frisch
W
W
Milbradt
R
R
Holzmann
H
H
D000293:Adolescent; D000328:Adult; D000911:Antibodies, Monoclonal; D000943:Antigens, Differentiation / Q000032:analysis*; D018955:CD36 Antigens; D005260:Female; D006801:Humans; D015603:Keratinocytes / Q000276:immunology; D007801:Langerhans Cells / Q000276:immunology; D007958:Leukocyte Count; D008297:Male; D008544:Melanocytes / Q000276:immunology; D008875:Middle Aged; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D014820:Vitiligo / Q000276:immunology*
D000911:Antibodies, Monoclonal; D000943:Antigens, Differentiation; D018955:CD36 Antigens
Erhöhte Expression des OKM5-Antigens auf Blutmonozyten bei Vitiligo.