title: Alpha-fetoprotein in tumours derived from cystic and simple embryoid bodies.
abstract: Cellular aggregates called embryoid bodies (EB) have been obtained from the experimental teratocarcinoma (TC) 0TT6050. Two morphological types of EB can be differentiated, which are injected subcutaneously into isogenic 129/Sv mice. The tumors are collected 20 and 30 days after EB injection and processed histologically, and immunohistochemically with anti-alpha-fetoprotein (alpha-FP) antibodies. Our results indicate that the histological pattern of the tumors is related to the degree of morphological organization of the EB used.
authors.affiliation: Department of Morphological Sciences, Faculty of Medicine, University of Barcelona, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Monzó
authors.forename: J M
authors.initials: JM
authors.lastname: de Anta
authors.forename: B
authors.initials: B
authors.lastname: Peris
authors.forename: D
authors.initials: D
authors.lastname: Ruano
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor / Q000032:analysis*; D002454:Cell Differentiation; D007279:Injections, Subcutaneous; D051379:Mice; D008815:Mice, Inbred Strains; D009363:Neoplasm Proteins / Q000032:analysis*; D009368:Neoplasm Transplantation; D009940:Organoids / Q000737:chemistry*; D013724:Teratoma / Q000737:chemistry / Q000473:pathology*; D000509:alpha-Fetoproteins / Q000032:analysis*
chemical_list: D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins; D000509:alpha-Fetoproteins