[Characteristics of cell membrane of B-lymphocytes in chronic lymphocytic leukemia. I. Expression of class II antigens (HLA-D)].
Surface expression of class II antigens (HLA-D) on B lymphocytes was studied in 47 patients with chronic lymphatic leukemia (CLL) with an aid of monoclonal antibodies against monomorphic determinants of DR, DP and DQ. An association was found between progression of disease and gradual loss of those markers, especially DP and DQ.
Pluta
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Kliniki Hematologii A. M. w Lublinie.
Górski
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Nowaczyk
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D000328:Adult; D000368:Aged; D000911:Antibodies, Monoclonal / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology* / Q000648:ultrastructure; D002462:Cell Membrane / Q000276:immunology; D000939:Epitopes / Q000032:analysis / Q000276:immunology; D005260:Female; D006682:HLA-DP Antigens / Q000032:analysis / Q000276:immunology*; D006683:HLA-DQ Antigens / Q000032:analysis / Q000276:immunology*; D006684:HLA-DR Antigens / Q000032:analysis / Q000276:immunology*; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000276:immunology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis
D000911:Antibodies, Monoclonal; D000939:Epitopes; D006682:HLA-DP Antigens; D006683:HLA-DQ Antigens; D006684:HLA-DR Antigens
Charakterystyka błonowa limfocytów B w przewlekłej białaczce limfatycznej. I. Ekspresja antygenów klasy II (HLA-D).