title: An X-ray microprobe facility using synchrotron radiation.
abstract: An X-ray microprobe for trace elemental analysis at micrometer spatial resolutions, using synchrotron radiation (SR), is under development. The facility consists of two beamlines, one including a 1:1 focusing mirror and the other an 8:1 ellipsoidal mirror. At present, "white light" is used for excitation of the characteristic X-ray fluorescence lines. Sensitivities in thin biological samples are in the range of 2-20 fg in 100 microns2 areas in 5 min irradiation times. Scanning techniques, as well as microtomography and chemical speciation, are discussed. Application to a specific biomedical study is included.
authors.affiliation: Department of Applied Science, Brookhaven National Laboratory, Upton, NY 11973.
authors.forename: B M
authors.initials: BM
authors.lastname: Gordon
authors.forename: K W
authors.initials: KW
authors.lastname: Jones
authors.forename: A L
authors.initials: AL
authors.lastname: Hanson
authors.forename: J G
authors.initials: JG
authors.lastname: Pounds
authors.forename: M L
authors.initials: ML
authors.lastname: Rivers
authors.forename: P
authors.initials: P
authors.lastname: Spanne
authors.forename: S R
authors.initials: SR
authors.lastname: Sutton
mesh_terms: D000818:Animals; D004577:Electron Probe Microanalysis / Q000295:instrumentation* / Q000379:methods; D010315:Particle Accelerators; D014131:Trace Elements / Q000032:analysis*
chemical_list: D014131:Trace Elements