[Plasmapheresis and/or intermediate high dosage immunoglobulin therapy--effective measures in threatened premature labor and intrauterine hemolysis in anti-PP1Pk (-Tja)?].
Anti-PP1Pk developed by women has been associated with abortion early in pregnancy and hemolytic disease of the newborn. The case of a 19-year-old woman who had had 2 spontaneous abortions in the first trimester is presented. When treated with plasma exchange and substituted with 5% albumin and intravenous immunoglobulin begun at six weeks' gestation and continued until the 30th week, she delivered a viable female infant without anemia. According to our data and review of literature, the effectiveness of therapy by plasmapheresis and/or immunoglobulin is discussed.
Heim
M U
MU
Transfusionszentrum, Universität München.
Weidemann
R
R
Brehm
G
G
Versmold
H
H
Mempel
W
W
D003131:Combined Modality Therapy; D004899:Erythroblastosis, Fetal / Q000097:blood / Q000517:prevention & control*; D005260:Female; D005317:Fetal Growth Retardation / Q000097:blood; D005865:Gestational Age; D006801:Humans; D007116:Immunization, Passive / Q000379:methods*; D007231:Infant, Newborn; D007518:Isoantibodies / Q000032:analysis*; D007752:Obstetric Labor, Premature / Q000097:blood / Q000517:prevention & control*; D010127:P Blood-Group System / Q000276:immunology*; D010951:Plasma Exchange / Q000379:methods; D010956:Plasmapheresis / Q000379:methods*; D011247:Pregnancy
D007518:Isoantibodies; D010127:P Blood-Group System
Plasmapherese und/oder mittelhochdosierte Immunoglobulintherapie--wirksame Massnahmen bei drohendem Frühabort und intrauteriner Hämolyse bei Anti-PP1Pk (-Tja)?