title: Intralesional bleomycin sulfate therapy for warts. A novel bifurcated needle puncture technique.
abstract: A multiple puncture technique using a bifurcated vaccination needle to introduce bleomycin sulfate (1 U/mL sterile saline solution) into warts resulted in elimination of 92% of a random series of 258 warts after a single treatment. Recurrence was not observed during a 6-month follow-up period. Six of the 66 patients required two to seven treatments for wart eradication, and four patients requested alternative therapy after initial failure with a single bleomycin treatment.
authors.affiliation: Department of Medicine, Medical College of Ohio, Toledo.
authors.forename: W B
authors.initials: WB
authors.lastname: Shelley
authors.forename: E D
authors.initials: ED
authors.lastname: Shelley
mesh_terms: D000293:Adolescent; D000328:Adult; D001761:Bleomycin / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015552:Injections, Intralesional / Q000379:methods; D008297:Male; D008875:Middle Aged; D012871:Skin Diseases / Q000188:drug therapy*; D014860:Warts / Q000188:drug therapy*
chemical_list: D001761:Bleomycin