Are frequent spike-waves during non-REM sleep in relation with an acquired neuro-psychological deficit in epileptic children?
In a population of 11 children with frequent spike waves during non REM sleep who had no neurological symptoms between birth and their first symptom, 3 groups were compared according to their neuropsychological performances. In the first group, the children had no intellectual deficit, in the second group, they had an acquired aphasia as in the Landau-Kleffner syndrome and in the third they had severe behavioural disorder and mental deterioration. The non REM sleep paroxysmic activity density tended to be highest in the third group, variable in the second group and moderate in the first group, and their topography was always generalized in the acute phase in groups II and III but asymmetrical in group I. The EEG anomalies disappeared during adolescence but in group II and III children a moderate to severe delay in school work persisted.
Billard
C
C
Centre Hospitalier Universitaire, France.
Autret
A
A
Lucas
B
B
Degiovanni
E
E
Gillet
P
P
Santini
J J
JJ
de Toffol
B
B
D001037:Aphasia / Q000209:etiology / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007360:Intelligence / Q000502:physiology*; D008297:Male; D009483:Neuropsychological Tests; D012890:Sleep / Q000502:physiology*