Concentration of hyaluronectin and anionic glycoconjugates in perineuronal glial cell processes at GABAergic synapses of rat cerebellum.
Hyaluronectin was detected in the rat cerebellum using monospecific polyclonal antibodies at the light and electron microscopic level. The immunoreactivity was associated in the grey matter with glial (astrocytic) cell processes of perineuronal glial sheets but could not be found in glial cell bodies nor in neurons. This molecular specialization of grey matter astrocyte expansions was distinctly expressed at known sites of GABAergic synaptic transmission.
Brückner
G
G
Paul Flechsig Institute for Brain Research, Department of Neurochemistry, Karl Marx University, Leipzig.
Delpech
B
B
Delpech
A
A
Girard
N
N
D000818:Animals; D002352:Carrier Proteins / Q000032:analysis*; D002531:Cerebellum / Q000166:cytology*; D005260:Female; D006001:Glycoconjugates / Q000032:analysis*; D018960:Hyaluronan Receptors; D006820:Hyaluronic Acid / Q000378:metabolism; D007150:Immunohistochemistry; D016253:Microscopy, Immunoelectron; D009457:Neuroglia / Q000166:cytology* / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains; D013569:Synapses / Q000648:ultrastructure*; D005680:gamma-Aminobutyric Acid / Q000032:analysis*
D002352:Carrier Proteins; D006001:Glycoconjugates; D018960:Hyaluronan Receptors; D005680:gamma-Aminobutyric Acid; D006820:Hyaluronic Acid