Structure of respiratory allergens.
Respiratory allergens from one of the most important group of allergens. Except for professional allergens they are characterized by an enormous heterogeneity including a restricted number of major allergens. By means of modern immunological, chemical and genetic techniques some of them are, at least partially, characterized. Immunogenicity depends on a restricted area of the molecules. These epitopes seem to be in principle different for B cells (antibodies) and T cells. The strategies to improve immunodiagnosis are, therefore, not necessarily identical with those for the development of immunotherapy. The present data on selected respiratory allergens are summarized.
Jäger
L
L
Dept. of clinical Immunology, University Jena/Germany.
D000485:Allergens / Q000276:immunology*; D000818:Animals; D004175:Diptera / Q000276:immunology; D004391:Dust; D000939:Epitopes / Q000276:immunology; D006684:HLA-DR Antigens / Q000276:immunology; D006801:Humans; D008925:Mites / Q000276:immunology; D015394:Molecular Structure; D011058:Pollen / Q000276:immunology; D011948:Receptors, Antigen, T-Cell / Q000276:immunology; D012130:Respiratory Hypersensitivity / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
D000485:Allergens; D004391:Dust; D000939:Epitopes; D006684:HLA-DR Antigens; D011948:Receptors, Antigen, T-Cell