title: Ultrastructure of phagocytizing cells of the rat hypothalamic neurosurgery nuclei in a remote period after the sustained clinical death.
abstract: Ultrastructural studies were carried out on neurosecretory nuclei taken from brains of rats which have survived for 16 weeks following clinical death of 5 or 10 min duration. The reported observations indicate that brain lesions were caused by changes due to ischemia and superimposed secondary changes resulting from the maturation of pathological processes. In animals subjected to clinical death for 5 min the observed cells in the perivascular area were integrated in the capillary wall and wrapped by the basement membrane. Sometimes they were accompanied by cells engaged in the process of phagocytosis. Phagocytizing cells were more frequently noted in the animals subjected to clinical death for 10 min and then their cytoplasmic processes were connected with the adjacent capillaries. We assume that these cells, which may represent cerebral macrophages occur by transformation of pericytes or blood derived monocytes.
authors.affiliation: Laboratory of the Ultrastructure of the Nervous System, Medical Research Centre, Polish Academy of Sciences, Warsaw.
authors.forename: M
authors.initials: M
authors.lastname: Walski
authors.forename: R
authors.initials: R
authors.lastname: Celary-Walska
authors.forename: J
authors.initials: J
authors.lastname: Borowicz
mesh_terms: D000818:Animals; D002545:Brain Ischemia / Q000473:pathology; D003643:Death; D007031:Hypothalamus / Q000473:pathology / Q000648:ultrastructure*; D010286:Paraventricular Hypothalamic Nucleus / Q000473:pathology; D010586:Phagocytes / Q000648:ultrastructure*; D051381:Rats; D013194:Staining and Labeling; D013495:Supraoptic Nucleus / Q000473:pathology