An X-ray microprobe facility using synchrotron radiation.
An X-ray microprobe for trace elemental analysis at micrometer spatial resolutions, using synchrotron radiation (SR), is under development. The facility consists of two beamlines, one including a 1:1 focusing mirror and the other an 8:1 ellipsoidal mirror. At present, "white light" is used for excitation of the characteristic X-ray fluorescence lines. Sensitivities in thin biological samples are in the range of 2-20 fg in 100 microns2 areas in 5 min irradiation times. Scanning techniques, as well as microtomography and chemical speciation, are discussed. Application to a specific biomedical study is included.
Gordon
B M
BM
Department of Applied Science, Brookhaven National Laboratory, Upton, NY 11973.
Jones
K W
KW
Hanson
A L
AL
Pounds
J G
JG
Rivers
M L
ML
Spanne
P
P
Sutton
S R
SR
D000818:Animals; D004577:Electron Probe Microanalysis / Q000295:instrumentation* / Q000379:methods; D010315:Particle Accelerators; D014131:Trace Elements / Q000032:analysis*
D014131:Trace Elements