Intralesional bleomycin sulfate therapy for warts. A novel bifurcated needle puncture technique.
A multiple puncture technique using a bifurcated vaccination needle to introduce bleomycin sulfate (1 U/mL sterile saline solution) into warts resulted in elimination of 92% of a random series of 258 warts after a single treatment. Recurrence was not observed during a 6-month follow-up period. Six of the 66 patients required two to seven treatments for wart eradication, and four patients requested alternative therapy after initial failure with a single bleomycin treatment.
Shelley
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Department of Medicine, Medical College of Ohio, Toledo.
Shelley
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D000293:Adolescent; D000328:Adult; D001761:Bleomycin / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015552:Injections, Intralesional / Q000379:methods; D008297:Male; D008875:Middle Aged; D012871:Skin Diseases / Q000188:drug therapy*; D014860:Warts / Q000188:drug therapy*
D001761:Bleomycin