Dysgerminoma of the ovary. Cytologic, histologic and electron microscopic study of a case.
A case of ovarian dysgerminoma is reported. Both histology and cytology showed cells with distinctive anisokaryosis and large, sometimes bizarre, nucleoli as the most striking feature. A lymphocytic infiltration was present. Electron microscopy showed large convoluted nucleoli, structures resembling so-called "annulated lamellae" and glycogen particles, features that are typical of a germ-cell tumor. The cytologic, histologic and ultrastructural investigations revealed a dysgerminoma; that diagnosis was not certain on the frozen sections.
Hees
K
K
Department of Pathology, Municipal Hospital, Cologne, Federal Republic of Germany.
de Jonge
J P
JP
von Kortzfleisch
D H
DH
D000328:Adult; D002466:Cell Nucleolus / Q000648:ultrastructure; D004407:Dysgerminoma / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D015388:Organelles / Q000648:ultrastructure; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy / Q000648:ultrastructure; D013194:Staining and Labeling