Metabolic deposition of selenium and cadmium into the hair and other tissues of the guinea pig.
To better understand the significance of hair trace-element measurements and their relationships with the trace-element levels in body organs and fluids, a series of controlled animal experiments were conducted in which several trace elements were periodically measured during a 90-day chronic exposure to selenium and cadmium. Chronic selenium exposure appeared to be reflected by elevated selenium levels in the hair, kidneys, and liver. Chronic cadmium exposure, although reflected by kidney and liver elevation, appeared not to be reflected by corresponding increases in its concentration in the hair.
Chatt
A
A
Trace Analysis Research Centre, Dalhousie University, Halifax, Nova Scotia, Canada.
Holzbecher
J
J
Katz
S A
SA
D000818:Animals; D002104:Cadmium / Q000008:administration & dosage / Q000378:metabolism*; D006168:Guinea Pigs; D006197:Hair / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D009501:Neutron Activation Analysis; D012643:Selenium / Q000008:administration & dosage / Q000378:metabolism*; D013997:Time Factors; D014018:Tissue Distribution
D002104:Cadmium; D012643:Selenium