Morphometric and biochemical evaluation of rat prostate and seminal vesicle following chemical sympathectomy with guanethidine.
Selective chemical sympathectomy of the internal genital organs of adult male rats was undertaken by chronic treatment with low doses of guanethidine. Biochemical and morphometric methods revealed that removal of sympathetic innervation prevents fructose secretion in the prostate and seminal vesicle, in addition to promoting reduced efficiency of delivery by the latter.
Carvalho
T L
TL
Laboratory of (1) Pathology, Faculty of Odontology, Ribeiräo Preto, USP, Brasil.
Petenusci
S O
SO
Favaretto
A L
AL
Kempinas
W G
WG
D000818:Animals; D005632:Fructose / Q000378:metabolism; D006145:Guanethidine; D008297:Male; D009929:Organ Size; D011469:Prostatic Diseases / Q000378:metabolism / Q000628:therapy*; D051381:Rats; D011919:Rats, Inbred Strains; D012669:Seminal Vesicles / Q000378:metabolism*; D013563:Sympathectomy, Chemical; D013739:Testosterone / Q000097:blood
D005632:Fructose; D013739:Testosterone; D006145:Guanethidine