title: Chorionic villus sampling: analysis of fetal losses to delivery, placental pathology, and cervical microbiology.
abstract: A population of 1639 patients were seen for chorionic villus sampling (CVS). Embryonic death was identified at ultrasound in 5.3 per cent of patients. The number of patients undergoing CVS was 1551, with 1416 transcervical procedures and 135 transabdominal procedures. The most common indication for CVS was advanced maternal age. Spontaneous pregnancy losses identified by increased risk of pregnancy loss with increasing aspiration attempts. The total fetal loss for this population was 5.4 per cent with the pregnancy loss estimated due to procedure being 1.2 per cent. Analysis of placentae from patients having CVS and amniocentesis showed no differences. Microbiological assessment prior to CVS was similar to previous publications.
authors.affiliation: University of British Columbia, Grace Hospital Department of Obstetrics and Gynecology, Vancouver, Canada.
authors.forename: R D
authors.initials: RD
authors.lastname: Wilson
authors.forename: K
authors.initials: K
authors.lastname: Cho
authors.forename: B
authors.initials: B
authors.lastname: McGillivray
authors.forename: D
authors.initials: D
authors.lastname: Kalousek
authors.forename: D
authors.initials: D
authors.lastname: Shaw
authors.forename: V
authors.initials: V
authors.lastname: Baldwin
mesh_terms: D000328:Adult; D001424:Bacterial Infections / Q000175:diagnosis; D002177:Candidiasis / Q000175:diagnosis; D002584:Cervix Uteri / Q000382:microbiology*; D015193:Chorionic Villi Sampling / Q000009:adverse effects*; D002869:Chromosome Aberrations / Q000175:diagnosis; D025063:Chromosome Disorders; D005260:Female; D005313:Fetal Death / Q000209:etiology*; D005500:Follow-Up Studies; D006194:Gardnerella vaginalis; D006801:Humans; D009436:Neural Tube Defects / Q000175:diagnosis / Q000378:metabolism; D010920:Placenta / Q000473:pathology*; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D013290:Streptococcal Infections / Q000175:diagnosis; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D000509:alpha-Fetoproteins