Effect of conditioned medium on recovery of circulating blood cells in irradiated mice.
The effect of supernatant of thymus-cell conditioned medium (TCCM) on blood element recovery in peripheral blood was followed in mice exposed to a single whole body dose of 5.8 Gy of gamma radiation. As follows from our results. TCCM administered 18 h before irradiation accelerated the recovery of the reticulocyte and, in part, thrombocyte and granulocyte counts. However, no effect on the rate of lymphocyte recovery was found.
Macková
N
N
Institute of General Biology, Faculty of Science, P. J. Safarik University, Kosice, Czechoslovakia.
Fedorocko
P
P
Brezáni
P
P
D000818:Animals; D003470:Culture Media; D004906:Erythrocyte Count / Q000528:radiation effects*; D005260:Female; D005720:Gamma Rays; D006098:Granulocytes / Q000528:radiation effects; D007958:Leukocyte Count / Q000528:radiation effects*; D051379:Mice; D008810:Mice, Inbred C57BL; D010976:Platelet Count / Q000528:radiation effects*; D012156:Reticulocytes / Q000528:radiation effects*; D013950:Thymus Gland / Q000502:physiology*; D014916:Whole-Body Irradiation
D003470:Culture Media