Connatal rickets following repeated administration of phosphate enemas in pregnancy: a case report.
We present a case of antenatal failure of bone growth and mineralisation in a newborn whose anorectic mother repeatedly administered hypertonic phosphate enemas during pregnancy. Phosphate overload in pregnant women appears to impede calcification of the fetal skeleton.
Rimensberger
P
P
Children's Hospital, Lucerne, Switzerland.
Schubiger
G
G
Willi
U
U
D001846:Bone Development / Q000187:drug effects; D004733:Enema; D005260:Female; D006801:Humans; D006996:Hypocalcemia / Q000150:complications; D007231:Infant, Newborn; D007234:Infant, Premature; D008431:Maternal-Fetal Exchange; D009748:Nutrition Disorders / Q000378:metabolism*; D010710:Phosphates / Q000008:administration & dosage / Q000009:adverse effects*; D011247:Pregnancy; D011248:Pregnancy Complications; D011859:Radiography; D012279:Rickets / Q000139:chemically induced / Q000151:congenital* / Q000000981:diagnostic imaging
D010710:Phosphates