Anabolism and mechanism of action of Ro24-5098, an isomer of 2',3'-dideoxyadenosine (ddA) with anti-HIV activity.
Frank
K B
KB
Roche Research Center, Hoffmann-La Roche Inc., Nutley, New Jersey 07110-1199.
Connell
E V
EV
Holman
M J
MJ
Huryn
D M
DM
Sluboski
B C
BC
Tam
S Y
SY
Todaro
L J
LJ
Weigele
M
M
Richman
D D
DD
Mitsuya
H
H
D000998:Antiviral Agents / Q000494:pharmacology*; D016048:Dideoxyadenosine / Q000031:analogs & derivatives* / Q000494:pharmacology*; D006678:HIV / Q000187:drug effects* / Q000201:enzymology; D006801:Humans; D007536:Isomerism; D018894:Reverse Transcriptase Inhibitors
D000998:Antiviral Agents; D018894:Reverse Transcriptase Inhibitors; C067988:Ro 24-5098; D016048:Dideoxyadenosine