title: Aprotinin used in emergency coronary operation after streptokinase treatment.
abstract: We describe a patient with evolving myocardial infarction who underwent emergency intracoronary thrombolysis followed by immediate coronary artery grafting. Aprotinin was administered intraoperatively to control the potential bleeding problems associated with thrombolysis. Total postoperative blood loss was 260 mL. The case illustrates a further use for aprotinin in cardiac operations when excessive bleeding is anticipated.
authors.affiliation: Department of Cardiothoracic Surgery, Hammersmith Hospital, London, England.
authors.forename: T
authors.initials: T
authors.lastname: Efstratiadis
authors.forename: C
authors.initials: C
authors.lastname: Munsch
authors.forename: D
authors.initials: D
authors.lastname: Crossman
authors.forename: K
authors.initials: K
authors.lastname: Taylor
mesh_terms: D007611:Aprotinin / Q000627:therapeutic use*; D016063:Blood Loss, Surgical / Q000517:prevention & control*; D003131:Combined Modality Therapy; D001026:Coronary Artery Bypass; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000628:therapy*; D013300:Streptokinase / Q000627:therapeutic use*; D015912:Thrombolytic Therapy / Q000009:adverse effects*
chemical_list: D007611:Aprotinin; D013300:Streptokinase