title: Magnetic resonance imaging in children with spastic diplegia: correlation with the severity of their motor and mental abnormality.
abstract: Magnetic resonance imaging (MRI) findings for 34 children with spastic diplegia, examined between two and 10 years of age, were analysed. Dilatation of the trigone, atrophy of the peritrigonal white matter and prominent deep cortical sulci were seen. On T2-weighted images, periventricular high-intensity areas in the white matter adjacent to the trigones and bodies of the lateral ventricles were seen in many children. These MRI features may reflect the pathological changes of periventricular leukomalacia in children with spastic diplegia. Among the MRI findings, only the amount of white matter correlated with severity of disability: white matter reduction corresponded to the more severe motor disabilities.
authors.affiliation: Department of Pediatric Neurology, Seirei-Hamamatsu General Hospital, Mikatabara, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Yokochi
authors.forename: K
authors.initials: K
authors.lastname: Aiba
authors.forename: M
authors.initials: M
authors.lastname: Horie
authors.forename: K
authors.initials: K
authors.lastname: Inukai
authors.forename: S
authors.initials: S
authors.lastname: Fujimoto
authors.forename: M
authors.initials: M
authors.lastname: Kodama
authors.forename: K
authors.initials: K
authors.lastname: Kodama
mesh_terms: D001921:Brain / Q000473:pathology*; D002547:Cerebral Palsy / Q000473:pathology* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007969:Leukomalacia, Periventricular / Q000473:pathology; D008124:Locomotion; D008279:Magnetic Resonance Imaging; D008297:Male; D009069:Movement Disorders / Q000503:physiopathology*