title: [Malignant lymphomatous polyposis of the gastrointestinal tract].
abstract: Two years after endoscopic excision of several polyps of the colon (histological examination revealing infiltration by a malignant non-Hodgkin lymphoma) a 67-year-old man was again found to have blood and mucus in his stool. Because local recurrence was suspected a coloscopy was performed. This revealed multiple polyps throughout the entire colon, predominantly in the sigmoid and rectum. Biopsy showed focal infiltration of the submucosa and mucosa with centrocytic non-Hodgkin lymphoma, compatible with the diagnosis of malignant lymphomatous polyposis of the gastrointestinal tract. Gastroduodenoscopy then demonstrated duodenal polyps and massive coarsening of the gastric folds due to infiltration. For the first time tumour masses were also found in the epipharynx. After 6 chemotherapy cycles according to the CHOP scheme (day 1: cyclophosphamide, 1500 mg, adriblastin, 100 mg and vincristine, 2 mg; days 1-5: prednisolone, 100 mg) all lymphoma infiltrates regressed completely. The patient has been symptom-free for 9 months.
authors.affiliation: II. Medizinische Klinik, Universität Wien.
authors.forename: L
authors.initials: L
authors.lastname: Erlacher
authors.forename: A
authors.initials: A
authors.lastname: Wagner
authors.forename: P
authors.initials: P
authors.lastname: Knoflach
authors.forename: A
authors.initials: A
authors.lastname: Chott
authors.forename: A
authors.initials: A
authors.lastname: Luger
authors.forename: T
authors.initials: T
authors.lastname: Radaszkiewicz
authors.forename: M
authors.initials: M
authors.lastname: Zrunek
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003110:Colonic Neoplasms / Q000473:pathology / Q000628:therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D004724:Endoscopy; D005770:Gastrointestinal Neoplasms / Q000473:pathology / Q000628:therapy; D006801:Humans; D007417:Intestinal Polyps / Q000473:pathology / Q000628:therapy; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology / Q000628:therapy; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D012004:Rectal Neoplasms / Q000473:pathology / Q000628:therapy; D012811:Sigmoid Neoplasms / Q000473:pathology / Q000628:therapy; D013274:Stomach Neoplasms / Q000473:pathology / Q000628:therapy; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone
vernacular_title: Maligne lymphomatöse Polypose des Gastrointestinaltrakts.