title: Fibrous papule of the nose with granular cells: two cases.
abstract: Two cases of fibrous papule of the nose (FPN) with granular cell features are presented and discussed. Both lesions have classic architectural features of FPN; however, the main stromal cells show large cytoplasmic granules of the type seen in granular cells. We are uncertain of the significance of these findings. Our hypotheses include a perifollicular granular cell reaction and a granular degenerative change of local dermal dendrocytes.
authors.affiliation: Department of Pathology, Cleveland Clinic Foundation, Ohio 44195.
authors.forename: J
authors.initials: J
authors.lastname: Guitart
authors.forename: W F
authors.initials: WF
authors.lastname: Bergfeld
authors.forename: R J
authors.initials: RJ
authors.lastname: Tuthill
mesh_terms: D016586:Granular Cell Tumor / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D006651:Histocytochemistry; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009669:Nose Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D013194:Staining and Labeling