Immunoreactivity of canine and feline polyglucosan bodies for monoclonal antibody against human polyglucosan.
With the use of monoclonal antibodies, raised against the human polyglucosan, positive staining of polyglucosan bodies (PGB) was detected in the brain, spinal cord and cecum of aged dogs. PGB in feline brain were also positively stained with these antibodies. These findings indicate that animal PGB share common antigenicity with human PGB.
Kamiya
S
S
Department of Veterinary Anatomy, Nippon Veterinary and Zootechnical College, Tokyo, Japan.
Suzuki
Y
Y
Daigo
M
M
D000818:Animals; D000911:Antibodies, Monoclonal; D001921:Brain / Q000378:metabolism / Q000648:ultrastructure*; D002415:Cats; D002432:Cecum / Q000378:metabolism / Q000648:ultrastructure; D003594:Cytoplasmic Granules / Q000378:metabolism / Q000648:ultrastructure*; D004285:Dogs; D005936:Glucans / Q000276:immunology*; D006801:Humans; D007150:Immunohistochemistry; D013116:Spinal Cord / Q000378:metabolism / Q000648:ultrastructure*; D013194:Staining and Labeling
D000911:Antibodies, Monoclonal; D005936:Glucans