The pluripotent hemopoietic stem cell: its identification and applications.
The experiments leading to the concept of a pluripotent hemopoietic stem cell (PHSC) are reviewed. The identification and morphological characteristics of the PHSC are presented and a number of current and prospective applications of grafts of PHSC are described.
van Bekkum
D W
DW
Institute of Applied Radiobiology and Immunology TNO, Rijswijk, The Netherlands.
D000818:Animals; D002469:Cell Separation / Q000379:methods; D006412:Hematopoietic Stem Cells / Q000166:cytology* / Q000502:physiology / Q000648:ultrastructure; D051379:Mice; D008854:Microscopy, Electron