title: Use of low-osmolality contrast medium does not increase prevalence of medullary sponge kidney.
abstract: To assess the prevalence of intrapapillary linear collections of contrast medium as well as of homogeneous papillary blush on excretory urograms obtained with a low-osmolality contrast medium, iohexol was used in 300 patients. Intrapapillary linear collections of contrast medium (ie, three or more linear collections of contrast material within a papilla) were found in 10 (9.5%) of the 105 patients with renal stone disease and two (1.0%) of the 195 patients without nephrolithiasis (P less than .001). These prevalences are similar to those found in a previous study with use of a high-osmolality contrast medium (sodium amidotrizoate). The difference in the prevalence of homogeneous papillary blush between stone formers and non-stone formers was nonsignificant. The authors conclude that intrapapillary linear collections of contrast medium on excretory urograms obtained with use of a low-osmolality contrast medium should be considered to have the same clinical significance as those on excretory urograms obtained with use of a high-osmolality contrast medium, that is, as indicating the presence of medullary sponge kidney.
authors.affiliation: Department of Radiology, University Hospital, Lausanne, Switzerland.
authors.forename: J M
authors.initials: JM
authors.lastname: Ginalski
authors.forename: T
authors.initials: T
authors.lastname: Spiegel
authors.forename: P
authors.initials: P
authors.lastname: Jaeger
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007472:Iohexol; D007669:Kidney Calculi / Q000150:complications / Q000000981:diagnostic imaging; D007679:Kidney Medulla / Q000000981:diagnostic imaging*; D008297:Male; D007691:Medullary Sponge Kidney / Q000150:complications / Q000000981:diagnostic imaging*; D008875:Middle Aged; D009994:Osmolar Concentration; D011859:Radiography
chemical_list: D007472:Iohexol