Enzootic nasal tumour of goats: demonstration of a type D-related retrovirus in nasal fluids and tumours.
Nasal exudate and tumour tissue from goats with enzootic nasal tumours were shown to contain a reverse transcriptase activity associated with a particle of buoyant density typical of retroviruses. The same particle contained a 25,000 Mr protein that cross-reacted with the p27 of Mason-Pfizer monkey virus (MPMV) and with p25 of sheep pulmonary adenomatosis retrovirus. It also contained a low Mr protein related to p10-12 of MPMV.
De las Heras
M
M
Facultad de Veterinaria, Universidad de Zaragoza, Spain.
Sharp
J M
JM
Garcia de Jalon
J A
JA
Dewar
P
P
D000818:Animals; D015153:Blotting, Western / Q000662:veterinary; D015511:Goat Diseases / Q000201:enzymology / Q000382:microbiology*; D006041:Goats; D009669:Nose Neoplasms / Q000201:enzymology / Q000382:microbiology / Q000648:ultrastructure / Q000662:veterinary*; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism; D012190:Retroviridae / Q000201:enzymology / Q000302:isolation & purification* / Q000648:ultrastructure; D012192:Retroviridae Infections / Q000382:microbiology / Q000662:veterinary
D012194:RNA-Directed DNA Polymerase