How do viral reverse transcriptases recognize their RNA genome?
Reverse transcription is not solely a retroviral mechanism. Hepadnaviruses and caulimoviruses have RNA intermediates that are reverse transcribed into DNA. Moreover non-viral retroelements, retrotransposons, use reverse transcription in their transposition. All these retroelements encode reverse transcriptase but each group developed their own expression modes capable of assuring a specific and efficient replication of their genomes.
Mesnard
J M
JM
Institut de Biologie Moléculaire des Plantes du C.N.R.S., Université Louis Pasteur, Strasbourg, France.
Lebeurier
G
G
D002213:Capsid / Q000235:genetics / Q000378:metabolism; D004251:DNA Transposable Elements; D015497:HIV-1 / Q000201:enzymology; D015613:Hepadnaviridae / Q000201:enzymology / Q000235:genetics; D012367:RNA, Viral / Q000378:metabolism*; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism*; D012190:Retroviridae / Q000201:enzymology / Q000235:genetics; D014780:Viruses / Q000201:enzymology* / Q000235:genetics
D004251:DNA Transposable Elements; D012367:RNA, Viral; D012194:RNA-Directed DNA Polymerase