title: Crystallization of the Fab fragments of anti-peptide monoclonal antibodies and a complex with peptide.
abstract: The antigen-binding fragments of four monoclonal antibodies that cross-react with both the "loop" peptide of hen egg-white lysozyme (residues 57 to 84) against which they were raised, and with the native protein (HEL) have been crystallized. One of these fragments also crystallizes as a complex with the peptide antigen.
authors.affiliation: Laboratory of Molecular Biophysics, Oxford, Great Britain.
authors.forename: R E
authors.initials: RE
authors.lastname: Griest
authors.forename: P D
authors.initials: PD
authors.lastname: Jeffrey
authors.forename: G L
authors.initials: GL
authors.lastname: Taylor
authors.forename: A R
authors.initials: AR
authors.lastname: Rees
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000648:ultrastructure; D003461:Crystallography; D007140:Immunoglobulin Fab Fragments / Q000648:ultrastructure*; D007074:Immunoglobulin G / Q000737:chemistry; D046911:Macromolecular Substances; D051379:Mice; D009113:Muramidase / Q000737:chemistry / Q000276:immunology; D010455:Peptides / Q000737:chemistry* / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal; D007140:Immunoglobulin Fab Fragments; D007074:Immunoglobulin G; D046911:Macromolecular Substances; D010455:Peptides; D009113:Muramidase