title: Correlation between in vitro cytokine production and clinical evolution of multiple sclerosis patients.
abstract: In this preliminary study we demonstrated that cytokine production by short whole blood PHA stimulated culture is correlated with clinical evolution of MS patients. The TNF alpha production could forewarn the physician of a new relapse.
authors.forename: M
authors.initials: M
authors.lastname: Chofflon
authors.forename: C
authors.initials: C
authors.lastname: Juillard
authors.forename: G
authors.initials: G
authors.lastname: Gauthier
authors.forename: G E
authors.initials: GE
authors.lastname: Grau
mesh_terms: D001379:Azathioprine / Q000008:administration & dosage; D002478:Cells, Cultured; D003520:Cyclophosphamide / Q000008:administration & dosage; D016207:Cytokines / Q000096:biosynthesis*; D006801:Humans; D015592:Immunoradiometric Assay; D007371:Interferon-gamma / Q000096:biosynthesis; D007375:Interleukin-1 / Q000096:biosynthesis; D008137:Longitudinal Studies; D009000:Monocytes / Q000276:immunology; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D012008:Recurrence; D014409:Tumor Necrosis Factor-alpha / Q000096:biosynthesis
chemical_list: D016207:Cytokines; D007375:Interleukin-1; D014409:Tumor Necrosis Factor-alpha; D007371:Interferon-gamma; D003520:Cyclophosphamide; D001379:Azathioprine