[Prevention of recurrence of Sudeck's disease with calcitonin].
In patients suffering from, or with a history of, reflex sympathetic dystrophy (RSD), there is always a risk of exacerbation or reactivation of this disease after surgery or trauma. The use of calcitonin in the treatment of this type of disorder is well established. Starting in 1984, 18 patients with clinical symptoms of RSD or a history of this disease were given daily prophylactic treatment with salmon calcitonin (100 IU subcutaneously or as a spray). Ten of the patients underwent orthopaedic surgery and 8 received conservative treatment following trauma. The mean duration of prophylactic treatment was 4 days before and 23 days after surgery or trauma. Only one recurrence was observed (3 per cent). For comparison, a retrospective analysis of a group with the same inclusion criteria who underwent surgery or received conservative treatment after trauma, without prophylactic administration of calcitonin showed a recurrence of the underlying disease 28 per cent of the cases. It is therefore possible to recommend prophylactic administration of calcitonin, to patients with a history of RSD who are about to undergo orthopaedic surgery or conservative treatment following trauma.
Kissling
R O
RO
Clinique orthopédique universitaire Balgrist, Zurich, Suisse.
Bloesch
A C
AC
Sager
M
M
Dambacher
M A
MA
Schreiber
A
A
D000328:Adult; D002116:Calcitonin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009985:Orthopedics; D012008:Recurrence; D012019:Reflex Sympathetic Dystrophy / Q000188:drug therapy / Q000517:prevention & control*; D012086:Reoperation
D002116:Calcitonin
Prévention de la récidive d'une maladie de Sudeck par la calcitonine.