[Modulation of the surface antigens of Salmonella-phagocytized U937 cells].
In this study, modulation of the surface antigens of Salmonella enteritidis-phagocytized U937 cells and morphology of the bacteria in these cells were analyzed by the indirect immunofluorescence technique. The results are as follows: (1) Morphological studies revealed that the bacteria phagocytized by the U937 cells were transformed to a small coccoid form. (2) The expression of CD14 antigen was observed 24 to 48 h after phagocytosis. (3) The levels of CD11b and CD23 antigens were clearly enhanced 48 h after phagocytosis. (4) No modulation of HLA-class II (DR, DQ and DP) antigens was observed after phagocytosis.
Ikewaki
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Department of Microbiology, Kitasato University School of Nursing, Kanagawa, Japan.
D015703:Antigens, CD / Q000032:analysis; D000944:Antigens, Differentiation, B-Lymphocyte / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D000954:Antigens, Surface / Q000032:analysis*; D002478:Cells, Cultured; D006801:Humans; D018950:Lipopolysaccharide Receptors; D010586:Phagocytes / Q000276:immunology*; D010587:Phagocytosis; D011961:Receptors, Fc / Q000032:analysis; D017455:Receptors, IgE; D012477:Salmonella enteritidis / Q000648:ultrastructure*
D015703:Antigens, CD; D000944:Antigens, Differentiation, B-Lymphocyte; D015214:Antigens, Differentiation, Myelomonocytic; D000954:Antigens, Surface; D018950:Lipopolysaccharide Receptors; D011961:Receptors, Fc; D017455:Receptors, IgE