[The clinical information value of an immunoenzyme study of the tumor markers CA-19-9, CEA and AFP in cancer of the stomach, pancreas, colon and rectum].
Blood levels of CEA, CA 19-9 and AFP were assayed by immunoenzyme technique in 60 cases of gastric cancer, 15 patients with pancreatic cancer and 30 patients with colorectal cancer. CEA and CA 19-9 levels were found to depend upon stage and degree of tumor differentiation. Changes in the antigen levels in the course of treatment reflected the degree of its radicality. In application of the immunoenzyme assay, CA 19-9 level appeared most clinically relevant in gastric, pancreatic and colorectal cancers. CEA concentration can serve as an indicator of liver metastases. CA 19-9 and CEA levels can be used for monitoring and objective evaluation of treatment for gastric, pancreatic and colorectal cancer as well as for predicting response.
Ial'chenko
N A
NA
Lagutin
V D
VD
Lavik
N N
NN
Musin
I I
II
D015295:Antigens, Tumor-Associated, Carbohydrate / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood*; D001782:Blood Donors; D002272:Carcinoembryonic Antigen / Q000097:blood*; D003110:Colonic Neoplasms / Q000097:blood* / Q000175:diagnosis; D006801:Humans; D007124:Immunoenzyme Techniques; D008113:Liver Neoplasms / Q000097:blood / Q000556:secondary; D010190:Pancreatic Neoplasms / Q000097:blood* / Q000175:diagnosis; D010437:Peptic Ulcer / Q000097:blood; D012004:Rectal Neoplasms / Q000097:blood* / Q000175:diagnosis; D012680:Sensitivity and Specificity; D013274:Stomach Neoplasms / Q000097:blood* / Q000175:diagnosis; D000509:alpha-Fetoproteins / Q000032:analysis*
D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D000509:alpha-Fetoproteins
Klinicheskaia informativnost' immunofermentnogo issledovaniia opukholevykh markerov CA 19-9, REA i AFP pri rake zheludka, podzheludochnoĭ zhelezy, obodochnoĭ i priamoĭ kishki.