title: Histological analysis of ultrasonic images of the prostate: an accurate technique.
abstract: Ultrasonography of the prostate furnishes images which still cannot be fully interpreted morphologically. In a cadaver study, the ultrasound images of two groups (21 and 19) prostates, obtained in a water bath, were compared with histology slides taken at corresponding levels. In the first part of the study, using a 4 MHz probe, there was a correlation between hyperechoic lesions and stone formations in 9 out of 15 cases. A relation between hypoechoic lesions and the existence of a carcinoma could also be established in 4 out of 12 cases. In the second part of the study, using a 7 MHz probe, there was a correlation between hyperechoic lesions and stone formations in all cases. Hypoechoic lesions correlated with the presence of a carcinoma in 1 out of 8 cases. The technique used appears to be well suited for the comparative study of ultrasound images and histology. Application of the 7 MHz probe is preferable as, because of a better resolution, smaller lesions can be detected. The results of this study are not very encouraging for the use of transrectal ultrasound for the detection of small prostatic carcinomas.
authors.affiliation: Department of Urology, St. Radboud University Hospital, Nijmegen, The Netherlands.
authors.forename: A J
authors.initials: AJ
authors.lastname: Hendrikx
authors.forename: J J
authors.initials: JJ
authors.lastname: de la Rosette
authors.forename: C A
authors.initials: CA
authors.lastname: van Helvoort-van Dommelen
authors.forename: M A
authors.initials: MA
authors.lastname: van Dijk
authors.forename: H
authors.initials: H
authors.lastname: Semmelink
authors.forename: N V
authors.initials: NV
authors.lastname: Rijntjes
authors.forename: F M
authors.initials: FM
authors.lastname: Debruyne
mesh_terms: D000368:Aged; D002102:Cadaver; D006801:Humans; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000000981:diagnostic imaging* / Q000473:pathology; D011470:Prostatic Hyperplasia / Q000000981:diagnostic imaging*; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging*; D014463:Ultrasonography / Q000379:methods