Chronic mumps virus encephalitis.
A previously well 4-year-old girl developed frequent seizures and mental deterioration after mumps parotitis. Direct IgG antibody capture enzyme-linked immunosorbent assay revealed a high titer of anti-mumps viral antibodies in the cerebrospinal fluid. Chronic mumps encephalitis was diagnosed. Her mental state and seizures improved markedly with inosine pranobex therapy.
Ito
M
M
Department of Pediatrics, Faculty of Medicine, Kyoto University, Japan.
Go
T
T
Okuno
T
T
Mikawa
H
H
D000914:Antibodies, Viral / Q000134:cerebrospinal fluid; D000927:Anticonvulsants / Q000627:therapeutic use; D002675:Child, Preschool; D002908:Chronic Disease; D004569:Electroencephalography; D004660:Encephalitis / Q000188:drug therapy / Q000382:microbiology*; D004797:Enzyme-Linked Immunosorbent Assay; D004829:Epilepsy, Generalized / Q000188:drug therapy / Q000209:etiology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid; D007542:Inosine Pranobex / Q000627:therapeutic use; D009107:Mumps / Q000150:complications*; D009109:Mumps virus / Q000276:immunology / Q000472:pathogenicity*
D000914:Antibodies, Viral; D000927:Anticonvulsants; D007074:Immunoglobulin G; D007542:Inosine Pranobex