title: [The mechanisms of cellular complementarity in the erythroblast islands of the bone marrow].
abstract: Phenylhydrazine was shown to reduce the content of erythroblast islands (EI) within 24 hrs in the rat bone marrow, the effect depending on the dose. Simultaneous strengthening of phagocytic activity, acidifying of lysosomes central macrophages EI and lowering of electrophoretic mobility, were observed. The proteinase inhibitor contrycal (50 and 500 i. u.) prevented the effect in the EI and intensified the regeneration of erythron. In vitro, trypsin and chymotrypsin decreased the EI content in the marrow cell suspension. Changing of functional condition of the central macrophages EI and, probably, products of its secretion, seems to affect the cell complementing in EI.
authors.forename: A G
authors.initials: AG
authors.lastname: Rassokhin
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Zakharov
authors.forename: O G
authors.initials: OG
authors.lastname: Krest'ianinova
authors.forename: D G
authors.initials: DG
authors.lastname: Kruglov
authors.forename: P Iu
authors.initials: PIu
authors.lastname: Potapov
mesh_terms: D000818:Animals; D007611:Aprotinin / Q000494:pharmacology; D001853:Bone Marrow / Q000187:drug effects / Q000502:physiology*; D001854:Bone Marrow Cells; D002918:Chymotrypsin / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004586:Electrophoresis; D004900:Erythroblasts / Q000187:drug effects / Q000502:physiology*; D004920:Erythropoiesis / Q000187:drug effects / Q000502:physiology; D006863:Hydrogen-Ion Concentration; D008247:Lysosomes / Q000187:drug effects / Q000502:physiology; D008297:Male; D010659:Phenylhydrazines / Q000494:pharmacology; D051381:Rats; D013997:Time Factors; D014357:Trypsin / Q000494:pharmacology
chemical_list: D010659:Phenylhydrazines; C030299:phenylhydrazine; D007611:Aprotinin; D002918:Chymotrypsin; D014357:Trypsin
vernacular_title: O nekotorykh mekhanizmakh komplementarnosti kletok v éritroblasticheskikh ostrovkakh kostnogo mozga.