title: Surgical management of pain.
abstract: This article presents an overview of the neuroanatomical, neurochemical, and neurophysiological substrates of nociception relevant to the neurosurgical treatment of chronic pain. Consideration is given to the various procedures currently employed in the treatment of patients suffering from medically intractable chronic pain of both benign and malignant diseases, including their indications, techniques, and results. Particular attention is given to the modern neuroaugmentative methods, such as electrical stimulation and CNS drug infusion, that are progressively overshadowing the previously developed ablative procedures.
authors.affiliation: Division of Neurosurgery, University of Medicine and Dentristy of New Jersey-Robert Wood Johnson Medical School, New Brunswick.
authors.forename: R R
authors.initials: RR
authors.lastname: Goodman
mesh_terms: D002908:Chronic Disease; D004558:Electric Stimulation; D006801:Humans; D009369:Neoplasms / Q000503:physiopathology; D009619:Nociceptors / Q000503:physiopathology; D010146:Pain / Q000503:physiopathology / Q000601:surgery*; D010166:Palliative Care; D013116:Spinal Cord / Q000503:physiopathology / Q000601:surgery*