Antigen specificity of gamma delta T lymphocytes.
gamma delta T cells represent a new lymphocyte subset without a definitive functional assignment. Although in many ways similar to alpha beta T lymphocytes, they are clearly distinguished by their expression of a different set of T cell receptor genes, a different distribution in normal tissues, and perhaps also different ligand specificities. Because gamma delta T cells appear to be involved in a variety of human diseases, the determination of their biological role has become an important challenge for immunologists and researchers in related areas.
Born
W K
WK
Department of Medicine, National Jewish Center for Immunology and Respiratory Medicine, Denver, Colorado 80206.
O'Brien
R L
RL
Modlin
R L
RL
D000818:Animals; D015551:Autoimmunity; D000939:Epitopes / Q000276:immunology*; D006801:Humans; D007239:Infections / Q000276:immunology; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology* / Q000502:physiology
D000939:Epitopes; D016692:Receptors, Antigen, T-Cell, gamma-delta