Angiosarcoma of the skin overlying an irradiated breast.
A case of angiosarcoma of the breast which developed six and a half years after treatment for carcinoma of the same breast is reported. As a result of radiotherapy the breast manifested signs of chronic lymphedema prior to development of angiosarcoma. Although the aetiology in this case is uncertain, there was a past history of childhood naevus regressing spontaneously. Angiosarcoma is a well known complication following radiotherapy and lymphedema, and is likely to be seen more frequently as conservation treatment is used more commonly for patients with early breast cancer.
Badwe
R A
RA
ICRF Clinical Oncology Unit, Guy's Hospital, London, UK.
Hanby
A M
AM
Fentiman
I S
IS
Chaudary
M A
MA
D001943:Breast Neoplasms / Q000532:radiotherapy*; D005260:Female; D006394:Hemangiosarcoma / Q000209:etiology / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000473:pathology*; D016609:Neoplasms, Second Primary / Q000209:etiology / Q000473:pathology*; D012878:Skin Neoplasms / Q000209:etiology / Q000473:pathology*