title: [Clinical study of the effectiveness of a preservative-free tear substitute].
abstract: 57 patients with dry eye syndrome of various etiology were treated with a preservative-free hydrogel in an open clinical trial. All patients enrolled in the 12 weeks study had a history of pretreatment with usual commercial tear substitutes which was either insufficient for relief of complaints or caused hypersensitivity. Detailed analysis of patients self assessment of their condition (by means of a linear scale), tear film break-up time, Schirmer Test, and physician's assessment of therapeutical results revealed that in about 90% of cases existing patient complaints and findings related to dry eye syndrome were significantly improved by symptomatic therapy with this preservative-free gel.
authors.affiliation: Augenklinik, Medizinischen Hochschule Hannover.
authors.forename: H
authors.initials: H
authors.lastname: Brewitt
authors.forename: P
authors.initials: P
authors.lastname: Joost
mesh_terms: D000368:Aged; D004342:Drug Hypersensitivity / Q000209:etiology; D015352:Dry Eye Syndromes / Q000628:therapy*; D005260:Female; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D007638:Keratoconjunctivitis Sicca / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011092:Polyethylene Glycols / Q000008:administration & dosage* / Q000009:adverse effects; D011310:Preservatives, Pharmaceutical
chemical_list: D011310:Preservatives, Pharmaceutical; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D011092:Polyethylene Glycols
vernacular_title: Klinische Studie zur Wirksamkeit eines nicht konservierten Tränenersatzmittels.