[The enhanced radioresistance (adaptive response) in vivo of splenic colony-forming units (CFU-S) following the exposure of mice to 60Co gamma rays at low doses].
An increase of resistance to radiation damage of human lymphocytes previously exposed to low doses of ionizing radiation from incorporated tritiated thymidine was observed by G. Olivieri et al. in 1984. The phenomenon was named adaptive response and its occurrence was reported by others for many animal and plant cells. In this research we studied the adaptive response of spleen colony formation at different time after previous irradiation of mice with low doses of 60Co gamma rays. Our results suggest that the pretreatments protect spleen colony-formatting units (CFU-S) from the second damaging radiation dose of 1.5 Gy during long time (as many as one month).
Saenko
A S
AS
Semenets
T N
TN
Semina
O V
OV
D000222:Adaptation, Physiological / Q000528:radiation effects*; D000818:Animals; D001853:Bone Marrow / Q000528:radiation effects; D001854:Bone Marrow Cells; D003037:Cobalt Radioisotopes; D003114:Colony-Forming Units Assay; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D006412:Hematopoietic Stem Cells / Q000166:cytology / Q000528:radiation effects*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D011836:Radiation Tolerance; D013154:Spleen / Q000166:cytology / Q000528:radiation effects*; D013997:Time Factors
D003037:Cobalt Radioisotopes
Povyshenie radiorezistentnosti (adaptivnyĭ otvet) in vivo selezenochnykh kononieobrazuiushchikh edinits (KOE-S) posle vozdeĭstviia na mysheĭ gamma-lucheĭ 60Co v malykh dozakh.