title: Cogan's syndrome. An unusual etiology of urticarial vasculitis.
abstract: We report the case of an 18-year-old black woman with urticarial vasculitis, vestibuloauditory dysfunction and superficial keratitis. Oral steroid therapy was effective in reducing most clinical manifestations with high-dosage dependency. However, only intravenous pulses of methylprednisolone allowed slight improvement of hearing. In this case, we emphasize urticarial vasculitis as a new manifestation of atypical Cogan's syndrome. A significant titer of Chalmydia trachomatis antibodies was found in our patient: their role in the pathogenesis of Cogan's syndrome is discussed.
authors.affiliation: Department of Dermatology, Hôpital Henri Mondor, Créteil, France.
authors.forename: S
authors.initials: S
authors.lastname: Ochonisky
authors.forename: O
authors.initials: O
authors.lastname: Chosidow
authors.forename: M
authors.initials: M
authors.lastname: Kuentz
authors.forename: N
authors.initials: N
authors.lastname: Man
authors.forename: S
authors.initials: S
authors.lastname: Fraitag
authors.forename: J M
authors.initials: JM
authors.lastname: Pelisse
authors.forename: J
authors.initials: J
authors.lastname: Revuz
mesh_terms: D000293:Adolescent; D003937:Diagnosis, Differential; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000473:pathology*; D006801:Humans; D007634:Keratitis / Q000473:pathology*; D007868:Leg Dermatoses / Q000473:pathology*; D013577:Syndrome; D014581:Urticaria / Q000473:pathology*; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000473:pathology*; D014717:Vertigo / Q000473:pathology*