title: [The diagnosis and possibilities for the anti-arrhythmia treatment of malignant ventricular disorders of the heart rhythm].
abstract: Altogether 130 patients with malignant ventricular disorders of cardiac rhythm were examined to demonstrate a possibility of obtaining the diagnostically significant data with the aid of Holter's monitoring of the ECG in 89.2%, with the aid of bicycle ergometry exercise tests in 72.3%, and by means of an electrophysiological examination of the heart in 82.5% of the above-indicated group of patients. The drug testing with the use of invasive and noninvasive techniques of monitoring the action of antiarrhythmic drugs given per os makes it possible to choose effective therapy on an individual basis. The long-term use of such therapy may prevent ventricular tachycardia relapses and noticeably enhance the patients' survival. Severe organic pathology of the heart associated with a decrease of its pump function seen in the majority of patients with malignant ventricular disorders of cardiac rhythm refractory to pharmacotherapy restricts, in a considerable number of cases, the potentialities of drastic surgical treatment because of the risk of operative death. To improve the disease prognosis of these patients, it is necessary that other methods of nonmedicamentous treatment may be used, requiring a less scope of surgical intervention, such as implantation of a cardioverter-defibrillator.
authors.forename: S P
authors.initials: SP
authors.lastname: Golitsyn
authors.forename: V I
authors.initials: VI
authors.lastname: Malakhov
authors.forename: S A
authors.initials: SA
authors.lastname: Bakalov
authors.forename: S F
authors.initials: SF
authors.lastname: Sokolov
authors.forename: I B
authors.initials: IB
authors.lastname: Krutanov
authors.forename: E R
authors.initials: ER
authors.lastname: Levin
authors.forename: G A
authors.initials: GA
authors.lastname: Mikhaĭlova
authors.forename: T V
authors.initials: TV
authors.lastname: Chernousova
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000175:diagnosis* / Q000188:drug therapy; D006328:Cardiac Catheterization; D002304:Cardiac Pacing, Artificial; D004359:Drug Therapy, Combination; D015716:Electrocardiography, Ambulatory; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013610:Tachycardia / Q000175:diagnosis / Q000188:drug therapy; D013614:Tachycardia, Paroxysmal / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D000889:Anti-Arrhythmia Agents
vernacular_title: Diagnostika i vozmozhnosti protivoaritmicheskogo lecheniia zlokachestvennykh zheludochkovykh narusheniĭ ritma serdtsa.