Electrophysiological study on a cochlear outer hair cell.
In order to examine the mechanoelectrical transduction of a cochlear hair cell, the electrical characteristics of the cochlear outer hair cell were studied. Both the cell dissociation technique and the patch clamp technique were used in this experiment. The membrane current gained by the voltage clamp method had a biphasic component, an initial inward current and a following outward current. After blocking the outward current by internal Cs ion and external TEA, the inward current has voltage-dependent inactivation. Also, the membrane potential change was studied by the current clamp method.
Sugata
Y
Y
Department of Otolaryngology, Hiroshima University, School of Medicine, Japan.
Harada
Y
Y
D000200:Action Potentials; D000818:Animals; D004594:Electrophysiology; D006168:Guinea Pigs; D006198:Hair Cells, Auditory / Q000502:physiology*; D008564:Membrane Potentials; D009991:Oscillometry