A normal 46,XX infant with a 46,XX/69,XXY placenta: a major contribution to the placenta is from a resorbed twin.
A predominantly triploid 69,XXY placenta was found associated with a normal 46,XX infant. Therefore, a triploid placenta is apparently capable of supporting normal fetal development. The chromosome and pathological results support the conclusion that the triploid placenta originates from a 'vanishing twin' pregnancy. This case is unusual in that persistence of the placenta from the vanished twin has virtually replaced most of the normal placenta.
Callen
D F
DF
Department of Cytogenetics and Molecular Genetics, Adelaide Children's Hospital, South Australia.
Fernandez
H
H
Hull
Y J
YJ
Svigos
J M
JM
Chambers
H M
HM
Sutherland
G R
GR
D000649:Amniocentesis; D015193:Chorionic Villi Sampling; D005260:Female; D005317:Fetal Growth Retardation / Q000175:diagnosis; D005327:Fetal Resorption / Q000235:genetics*; D006801:Humans; D007621:Karyotyping; D009030:Mosaicism; D010920:Placenta / Q000473:pathology / Q000648:ultrastructure*; D011123:Polyploidy; D011247:Pregnancy; D011272:Pregnancy, Multiple; D014427:Twins