title: Intrauterine insemination outperforms intracervical insemination in a randomized, controlled study with frozen, donor semen.
abstract: OBJECTIVE
  To assess the efficacy of intrauterine insemination (IUI) in a donor insemination program.
  
  
  METHODS
  Prospective randomized clinical trial.
  
  
  METHODS
  Donor insemination program.
  
  
  METHODS
  Women undergoing insemination were randomly assigned to receive either IUI or intracervical insemination for a maximum of six cycles.
  
  
  METHODS
  None.
  
  
  METHODS
  Cycle fecundity rates between the two routes were compared.
  
  
  RESULTS
  The monthly fecundity rate for intracervical insemination was 5.1% compared with 23% by IUI. By life table analysis, pregnancy rates for IUI were significantly higher than intracervical insemination (P = 0.02).
  
  
  CONCLUSIONS
  Intrauterine insemination with quarantined donor sperm is superior to intracervical insemination.
authors.affiliation: Department of Obstetrics and Gynecology, Oregon Health Sciences University, Portland.
authors.forename: P E
authors.initials: PE
authors.lastname: Patton
authors.forename: K A
authors.initials: KA
authors.lastname: Burry
authors.forename: A
authors.initials: A
authors.lastname: Thurmond
authors.forename: M J
authors.initials: MJ
authors.lastname: Novy
authors.forename: D P
authors.initials: DP
authors.lastname: Wolf
mesh_terms: D002584:Cervix Uteri; D005260:Female; D005615:Freezing; D006801:Humans; D007316:Insemination, Artificial, Heterologous / Q000379:methods*; D015993:Life Tables; D008297:Male; D008597:Menstrual Cycle; D009845:Oligospermia; D011247:Pregnancy; D011256:Pregnancy Outcome; D011446:Prospective Studies; D012661:Semen; D014599:Uterus