Renal insufficiency due to bilateral primary renal lymphoma.
Diffusely enlarged nonhydronephrotic kidneys on ultrasound and computer-tomographic examination in a case of progressive preterminal renal insufficiency were very suggestive of extensive lymphomatous infiltration. Diffuse infiltration of the kidney by centrocytic/centroblastic non-Hodgkin lymphoma was confirmed upon renal biopsy. No other localizations of lymphoma could be found. After four courses of CHOP chemotherapy there was a complete remission of this primary renal non-Hodgkin lymphoma, with complete recovery of renal function.
van Gelder
T
T
Department of Internal Medicine, University Hospital Rotterdam, The Netherlands.
Michiels
J J
JJ
Mulder
A H
AH
Klooswijk
A I
AI
Schalekamp
M A
MA
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging; D007674:Kidney Diseases / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D007680:Kidney Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D014750:Vincristine / Q000008:administration & dosage
D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone