Chronic effects of high salt intake and conflict stress on blood pressure in primates. A progress report.
The effects of combined behavioral stress and high dietary salt on blood pressure were examined in baboons (N = 4) over the course of 1 year. Either high salt diet (240 mEq Na+/day) or conflict stress were administered for 8 to 16 weeks, followed by high salt intake and stress combined. Mean arterial pressure (MAP) increased by 8 mmHg during high dietary salt alone, by 4 mmHg during stress alone, and increased further to 14 mmHg above baseline during combined salt and stress. Control baboons (N = 2) had no change in MAP across 47 weeks. The data indicate additive effects of chronic high dietary salt intake and behavioral stress on blood pressure in non-human primates.
Turkkan
J S
JS
Johns Hopkins University School of Medicine, Division of Behavioral Biology, Baltimore, MD 21205.
Goldstein
D S
DS
D000818:Animals; D001143:Arousal; D001794:Blood Pressure; D003220:Conflict, Psychological; D006973:Hypertension / Q000209:etiology* / Q000523:psychology; D008297:Male; D010215:Papio; D012307:Risk Factors; D012931:Social Environment; D012982:Sodium, Dietary / Q000009:adverse effects*; D013315:Stress, Psychological / Q000150:complications* / Q000523:psychology
D012982:Sodium, Dietary