Intraocular involvement with subretinal pigment epithelium infiltrates by mycosis fungoides.
We report a case of intraocular mycosis fungoides in a 48-year-old man. The patient presented with decreased visual acuity, white subretinal lesions, and vitritis. Post-mortem histopathology revealed malignant T cell infiltrates consistent with mycosis fungoides in the retina, vitreous, and between the retinal pigment epithelium (RPE) and Bruch's membrane Focal atrophy of the RPE, along with the sub-RPE infiltrates, correlated with the clinically visible fundus lesions.
Erny
B C
BC
Stanford University, Department of Ophthalmology, California 94305.
Egbert
P R
PR
Peat
I M
IM
Shorrock
K
K
Rosenthal
A R
AR
D016570:Bruch Membrane / Q000473:pathology; D005134:Eye Neoplasms / Q000473:pathology / Q000556:secondary*; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000473:pathology*; D010857:Pigment Epithelium of Eye / Q000473:pathology; D012160:Retina / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*; D014822:Vitreous Body / Q000473:pathology