title: Longterm neurological complications of chronic, habitual cocaine abuse.
abstract: We review and expand the results of several previously published studies on computed tomographic and electroencephalographic correlates of chronic, habitual cocaine abuse in order to present a complete spectrum of the longterm neurological complications of cocaine abuse. We argue that prolonged and frequent cocaine abuse leads to biochemical and vascular cerebral insults that eventually may cause functional and structural abnormalities affecting predominantly the fronto-temporal areas.
authors.affiliation: Medical Neurology Branch, National Institutes of Neurological Disorders and Stroke, NIH, Bethesda, Maryland 20892.
authors.forename: A
authors.initials: A
authors.lastname: Pascual-Leone
authors.forename: A
authors.initials: A
authors.lastname: Dhuna
authors.forename: D C
authors.initials: DC
authors.lastname: Anderson
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging; D003042:Cocaine; D004569:Electroencephalography / Q000187:drug effects; D006801:Humans; D019966:Substance-Related Disorders / Q000150:complications*; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D003042:Cocaine