title: [Measurement of local blood flow in the nasal mucosa by the method of hydrogen clearance].
abstract: The hydrogen clearance method was used to measure local blood flow in the inferior concha nasalis of 22 patients, aged 18 to 48 years. According to the method, the nasal mucosa was saturated with hydrogen and the rate of hydrogen washout was recorded in the form of hydrogen clearance curves. The response was tested by applying 0.1% epinephrine solution and the volume blood flow velocity was calculated. In response to epinephrine, blood flow velocity in the nasal mucosa diminished significantly. The hydrogen clearance method allowed an accurate quantitative evaluation of the volume blood flow velocity in a limited area of concha nasalis. The epinephrine test demonstrated a high sensitivity of the method that gave an adequate idea of mucosal microcirculation. This method, together with other procedures, can be used to examine the nasal mucosa.
authors.forename: V V
authors.initials: VV
authors.lastname: Shkabrov
authors.forename: I P
authors.initials: IP
authors.lastname: Sergeev
mesh_terms: D000293:Adolescent; D000328:Adult; D001783:Blood Flow Velocity / Q000502:physiology; D004867:Equipment Design; D006801:Humans; D006859:Hydrogen / Q000097:blood / Q000493:pharmacokinetics*; D008657:Metabolic Clearance Rate / Q000502:physiology; D008875:Middle Aged; D009297:Nasal Mucosa / Q000098:blood supply* / Q000378:metabolism; D010992:Plethysmography, Impedance / Q000295:instrumentation / Q000379:methods; D012039:Regional Blood Flow; D014586:USSR
chemical_list: D006859:Hydrogen
vernacular_title: Opredelenie lokal'nogo krovotoka v slizistoĭ obolochke nosa metodom klirensa vodoroda.