Cleft anterior segment with maternal hypervitaminosis A.
We report a case of an 'hourglass' cornea and iris with reduplicated lens in the left eye of an infant girl. An excess of vitamin A products had been taken by the mother during pregnancy. Mechanisms by which vitamin A excess could have caused this are discussed.
Evans
K
K
University of Liverpool, Children's Unit, Alder Hey Hospital, Ophthalmology Department, West Derby.
Hickey-Dwyer
M U
MU
D000014:Abnormalities, Drug-Induced / Q000209:etiology*; D000015:Abnormalities, Multiple / Q000139:chemically induced*; D000328:Adult; D003315:Cornea / Q000002:abnormalities*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007498:Iris / Q000002:abnormalities*; D007908:Lens, Crystalline / Q000002:abnormalities; D014801:Vitamin A / Q000009:adverse effects*
D014801:Vitamin A