title: Preliminary nuclear magnetic resonance studies on human saliva.
abstract: Of gustatory-stimulated human whole, parotid, submandibular and sublingual saliva only parotid saliva, a serous rather than mucous secretion, presented a relatively well-resolved proton NMR spectrum with satisfactory signal-to-noise ratio in a short time (30 min). The proton signal intensities showed significant circadian rhythms related to the circadian rhythms of protein concentrations in saliva. Age- and sex-associated differences in spectra were not observed for healthy saliva. On the other hand, marked differences in the spectra were observed for patients with suspected sialoadenitis.
authors.affiliation: Department of Oral Radiology, School of Dentistry, Tokushima University, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Yamada-Nosaka
authors.forename: S
authors.initials: S
authors.lastname: Fukutomi
authors.forename: S
authors.initials: S
authors.lastname: Uemura
authors.forename: T
authors.initials: T
authors.lastname: Hashida
authors.forename: M
authors.initials: M
authors.lastname: Fujishita
authors.forename: Y
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: Y
authors.initials: Y
authors.lastname: Kyogoku
mesh_terms: D000328:Adult; D002940:Circadian Rhythm; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D012463:Saliva / Q000737:chemistry* / Q000378:metabolism; D012471:Salivary Proteins and Peptides / Q000737:chemistry; D012793:Sialadenitis / Q000175:diagnosis*
chemical_list: D012471:Salivary Proteins and Peptides