title: Correlation of conjunctival impression cytology results with lacrimal function and age.
abstract: Impression specimens were obtained from the bulbar conjunctiva of 146 eyes of 73 healthy volunteers (mean age, 52 years). Goblet cell densities and nuclear-cytoplasmic (N/C) ratio were determined. Break-up time (BUT), Schirmer-I test (S-I), Rose Bengal scores (RBs) were also recorded. Using a simple linear regression analysis, no correlation between the number of Goblet cells and age, BUT and S-I was found. Negative correlation with RBs (P = 0.05) was found. The N/C ratio has a negative correlation (P less than 0.01) with age and RBs and a positive correlation with BUT (P less than 0.01) and S-I (P = 0.03).
authors.affiliation: Department of Ophthalmology, University of Ioannina, Greece.
authors.forename: C A
authors.initials: CA
authors.lastname: Paschides
authors.forename: G
authors.initials: G
authors.lastname: Petroutsos
authors.forename: K
authors.initials: K
authors.lastname: Psilas
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D002452:Cell Count; D003228:Conjunctiva / Q000166:cytology*; D003584:Cytological Techniques; D005260:Female; D006801:Humans; D007765:Lacrimal Apparatus / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D013666:Tears / Q000502:physiology