title: Laboratory assessment of feeding behavior in bulimia nervosa and healthy women: methods for developing a human-feeding laboratory.
abstract: We have designed a human-feeding laboratory to be used to study feeding behavior in patients with eating disorders. Twenty-one normal-weight bulimic subjects consumed 29.711 +/- 39.940 MJ (range 0.862-178.632 MJ; 7101 +/- 9546 kcal, range 206 to 42,694 kcal) in 24 h. In comparison, 11 healthy volunteer women, when instructed to eat ad lib for 48 h, ate 7.715 +/- 2.590 MJ (1844 +/- 619 kcal) during the first 24 h and 7665 +/- 1828 MJ (1832 +/- 437 kcal) during the second 24 h. Bulimics and control subjects had a similar number of eating intervals (6.6 +/- 2.6 vs 5.0 +/- 1.7); 72% of the bulimic subjects' meals were similar in size to the meals of the controls [167-4100 kJ (40-980 kcal)] but these meals were higher in carbohydrate and lower in fat in bulemic patients. Excessive caloric intake by bulimic subjects was because 28% of their meals were very large [range 4.427-28.150 MJ (1058-6728 kcal)]. Data gathered in a laboratory setting appears to be a reasonable replication of naturalistic feeding and suggest that such a laboratory may prove useful for future studies of feeding behaviors in humans.
authors.affiliation: University of Pittsburgh, School of Medicine, Department of Psychiatry, Western Psychiatric Institute and Clinic, PA 15212.
authors.forename: W H
authors.initials: WH
authors.lastname: Kaye
authors.forename: T E
authors.initials: TE
authors.lastname: Weltzin
authors.forename: M
authors.initials: M
authors.lastname: McKee
authors.forename: C
authors.initials: C
authors.lastname: McConaha
authors.forename: D
authors.initials: D
authors.lastname: Hansen
authors.forename: L K
authors.initials: LK
authors.lastname: Hsu
mesh_terms: D000328:Adult; D001835:Body Weight; D002032:Bulimia / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology*; D005247:Feeding Behavior; D005260:Female; D005502:Food; D006801:Humans; D007753:Laboratories; D009747:Nutritional Physiological Phenomena; D012016:Reference Values