Congenital hypothyroidism and cystic fibrosis.
We report a case of dysgenetic congenital hypothyroidism associated with cystic fibrosis. Impaired exocrine pancreatic secretion and/or transit abnormalities secondary to the treatment of meconium ileus resulted in decreased absorption of L-thyroxine and difficulties in management of hypothyroidism.
Depasse
C
C
Department of Paediatrics, Hôpital Universitaire des Enfants Reine Fabiola, Université Libre de Bruxelles, Belgium.
Chanoine
J P
JP
Casimir
G
G
Van Vliet
G
G
D003409:Congenital Hypothyroidism; D003550:Cystic Fibrosis / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D006801:Humans; D007037:Hypothyroidism / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D007077:Ileal Diseases / Q000150:complications* / Q000151:congenital / Q000175:diagnosis / Q000503:physiopathology; D007231:Infant, Newborn; D007418:Intestinal Pseudo-Obstruction / Q000150:complications* / Q000151:congenital / Q000175:diagnosis / Q000503:physiopathology; D008297:Male; D008470:Meconium / Q000502:physiology*; D010179:Pancreas / Q000503:physiopathology; D010186:Pancreatic Function Tests; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000503:physiopathology