title: Fixed breathing frequency decreases end-tidal PCO2 in humans.
abstract: We tested the effect of a fixed breathing frequency on the partial pressure of CO2 in the end-tidal air (PETCO2) in resting healthy subjects. In the first experiment, three different rates of breathing were dictated: the same frequency of breathing as the subject's control one (1f), a double frequency (2f), and half of the control frequency (0.5f). 10 min dictate of 1f and 2f induced a decrease of PETCO2. The dictate of 0.5f had no significant effect on PETCO2. In the second experiment, 1f was dictated for 30 min, inducing a decrease of PETCO2 throughout the duration of the dictate. These results demonstrate that fixing the breathing frequency by the dictate affects the chemostatic control of ventilation.
authors.affiliation: Institute of Pathophysiology, 2nd Medical Faculty, Charles University, Prague.
authors.forename: M
authors.initials: M
authors.lastname: Vízek
authors.forename: V
authors.initials: V
authors.lastname: Smejkal
authors.forename: F
authors.initials: F
authors.lastname: Palecek
mesh_terms: D000328:Adult; D002245:Carbon Dioxide / Q000378:metabolism*; D005260:Female; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D006985:Hyperventilation / Q000378:metabolism / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010313:Partial Pressure; D011659:Pulmonary Gas Exchange / Q000502:physiology*; D012119:Respiration / Q000502:physiology*; D013997:Time Factors
chemical_list: D002245:Carbon Dioxide