title: Exacerbation of fibrous dysplasia associated with an adolescent pregnancy.
abstract: Fibrous dysplasia is a metabolic skeletal disorder in which the medullary spaces of affected bones are replaced by fibro-osseous tissue. Patients with fibrous dysplasia usually become symptomatic during childhood; the adolescent patient we describe is unusual because she was not known to suffer from fibrous dysplasia until she became pregnant and experienced a dramatic reactivation of the symptoms. The therapeutic implication of this case and reproductive counselling for young women with fibrous dysplasia are discussed.
authors.affiliation: Department of Pediatrics, University of Colorado Health Science Center, Denver, Colorado.
authors.forename: C
authors.initials: C
authors.lastname: Stevens-Simon
authors.forename: J
authors.initials: J
authors.lastname: Stewart
authors.forename: I I
authors.initials: II
authors.lastname: Nakashima
authors.forename: M
authors.initials: M
authors.lastname: White
mesh_terms: D000293:Adolescent; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis