Correlation of serum ibuprofen concentration with clinical signs of toxicity in three canine exposures.
The clinical signs and serum concentrations of ibuprofen are reported for 3 canine exposures. No adverse clinical signs or abnormal laboratory parameters were observed when serum ibuprofen concentrations were less than 31 micrograms/mL. Melena and 38 mg blood urea nitrogen/dL (normal 7-26 mg/dL) were present in an animal with a serum ibuprofen of 138 micrograms/mL.
Jackson
T W
TW
Hennepin Regional Poison Center, Minneapolis, MN 55415.
Costin
C
C
Link
K
K
Heule
M
M
Murphy
M J
MJ
D000818:Animals; D004283:Dog Diseases / Q000139:chemically induced*; D004285:Dogs; D007052:Ibuprofen / Q000097:blood / Q000633:toxicity*; D008297:Male
D007052:Ibuprofen