title: Immune-mediated hemolysis associated with the administration of a radiographic contrast medium.
abstract: A female patient developed serious hemolysis in association with the injection of a radiographic contrast medium (RCM). Serologic investigation of her serum suggested complement-mediated hemolysis, induced by an RCM-dependent IgM antibody in her serum. The antibody was of high titer and low avidity. The antibody showed cross-reactions with related radiographic contrast media and reacted only with group I adult RBCs.
authors.affiliation: Department of Immunology, National Institute of Public Health, Oslo, Norway.
authors.forename: R
authors.initials: R
authors.lastname: Nordhagen
authors.forename: H
authors.initials: H
authors.lastname: Vik
authors.forename: K
authors.initials: K
authors.lastname: Wolthuis
authors.forename: H P
authors.initials: HP
authors.lastname: Bøhn
authors.forename: P
authors.initials: P
authors.lastname: Urdahl
authors.forename: T E
authors.initials: TE
authors.lastname: Michaelsen
mesh_terms: D003165:Complement System Proteins / Q000276:immunology; D003287:Contrast Media / Q000009:adverse effects*; D005260:Female; D006461:Hemolysis; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology; D008875:Middle Aged
chemical_list: D003287:Contrast Media; D007075:Immunoglobulin M; D003165:Complement System Proteins