Interferon-induced reversible acute renal failure with nephrotic syndrome.
Although there has been considerable experience with interferons in clinical trials during the past decade, acute renal failure as a side effect of interferon treatments has rarely been reported. We report a case in which acute renal failure with nephrotic syndrome was associated with therapy with two types of interferons. We note incomplete return of renal function upon withdrawal of therapy.
Nair
S
S
Division of Medical Oncology, University of Pittsburg, Pennsylvania.
Ernstoff
M S
MS
Bahnson
R R
RR
Arthur
S
S
Johnston
J
J
Downs
M A
MA
Neuhart
J
J
Kirkwood
J M
JM
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000368:Aged; D006801:Humans; D007370:Interferon Type I / Q000009:adverse effects* / Q000627:therapeutic use; D007371:Interferon-gamma / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D009404:Nephrotic Syndrome / Q000139:chemically induced*; D011994:Recombinant Proteins
D007370:Interferon Type I; D011994:Recombinant Proteins; D007371:Interferon-gamma