title: Visual recovery in two patients after intravenous methylprednisolone treatment of central retinal artery occlusion secondary to giant-cell arteritis.
abstract: Two patients with central retinal artery occlusions secondary to biopsy-proven giant-cell arteritis lost visual acuity to no light perception but recovered to baseline acuity after treatment with intravenous methylprednisolone at a dose of 15 to 30 mg/kg/day. The potential advantages and theoretical basis of early and aggressive treatment with large-dose intravenous corticosteroids in arteritic central retinal artery occlusion are discussed.
authors.affiliation: Department of Ophthalmology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY 10467.
authors.forename: D C
authors.initials: DC
authors.lastname: Matzkin
authors.forename: T L
authors.initials: TL
authors.lastname: Slamovits
authors.forename: R
authors.initials: R
authors.lastname: Sachs
authors.forename: R M
authors.initials: RM
authors.lastname: Burde
mesh_terms: D000368:Aged; D001706:Biopsy; D005260:Female; D013700:Giant Cell Arteritis / Q000150:complications*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use*; D015356:Retinal Artery Occlusion / Q000188:drug therapy / Q000209:etiology*; D016896:Treatment Outcome; D014786:Vision Disorders / Q000188:drug therapy* / Q000503:physiopathology; D014792:Visual Acuity
chemical_list: D008775:Methylprednisolone