title: [Atypical pathogen spectrum in community-acquired infections of the lower respiratory tract in childhood].
abstract: Over a period of 14 months, we obtained nasal and throat swabs for virological examinations from patients, admitted to hospital with suspected pneumonia. Fifty-five cases of perihilar bronchitis and 103 cases of pneumonia were diagnosed based on radiological criteria. In 36% (n = 57) of the children, a pathogen could be determined by antigen ELISA. We found the following spectrum: Respiratory syncytial virus: 42%; Influenza A: 8%; Influenza B: 10%; Parainfluenza 1: 3%; Parainfluenza 2: 10%; Parainfluenza 3: 2%; Chlamydia: 17%; and Mycoplasma pneumoniae (serology only): 7%. In a control group of 59 healthy children, only one child showed a pathogen. In the past, viruses and Chlamydia have been underestimated as causes of lower respiratory tract infections. Antigen determination by ELISA has proved to be a reliable and rapid method for their detection.
authors.affiliation: Zentrum der Kinderheilkunde, Universität Frankfurt am Main.
authors.forename: P
authors.initials: P
authors.lastname: Sehrt
authors.forename: S
authors.initials: S
authors.lastname: Zielen
authors.forename: H
authors.initials: H
authors.lastname: Rabenau
authors.forename: G
authors.initials: G
authors.lastname: Bauer
authors.forename: P
authors.initials: P
authors.lastname: Ahrens
authors.forename: D
authors.initials: D
authors.lastname: Hofmann
authors.forename: F
authors.initials: F
authors.lastname: Ball
authors.forename: H W
authors.initials: HW
authors.lastname: Doerr
mesh_terms: D000293:Adolescent; D000942:Antigens, Bacterial / Q000032:analysis; D000956:Antigens, Viral / Q000032:analysis; D001424:Bacterial Infections / Q000276:immunology / Q000382:microbiology*; D001431:Bacteriological Techniques; D001991:Bronchitis / Q000276:immunology / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D002690:Chlamydia Infections / Q000175:diagnosis / Q000276:immunology; D003937:Diagnosis, Differential; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011014:Pneumonia / Q000276:immunology / Q000382:microbiology*; D011019:Pneumonia, Mycoplasma / Q000175:diagnosis / Q000276:immunology; D011024:Pneumonia, Viral / Q000276:immunology / Q000382:microbiology*; D014777:Virus Diseases / Q000276:immunology / Q000382:microbiology*
chemical_list: D000942:Antigens, Bacterial; D000956:Antigens, Viral
vernacular_title: Atypisches Erregerspektrum bei ausserhalb der Klinik erworbenen Infektionen der tiefen Atemwege im Kindesalter.