title: [Percutaneous instillation of fluconazole in the treatment of pulmonary aspergilloma].
abstract: A 68-year-old woman had pulmonary aspergilloma in the right upper lobe with old cavitary pulmonary tuberculosis. Despite intravenous fluconazole there was no change in the size of the fungus ball. Endobronchial instillation of fluconazole also failed. Subsequently percutaneous instillation of fluconazole was attempted with localized drainage. The fungus ball decreased in size after 8 weeks. Although slight hemoptysis and subcutaneous emphysema occurred in this case, these condition required no treatment. This method of treatment appears to be useful for inoperable cases of pulmonary aspergilloma.
authors.affiliation: Third Department of Medicine, Medical College of Oita, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yoshimatsu
authors.forename: O
authors.initials: O
authors.lastname: Onizuka
authors.forename: T
authors.initials: T
authors.lastname: Matsumoto
authors.forename: T
authors.initials: T
authors.lastname: Tsuda
mesh_terms: D000279:Administration, Cutaneous; D000368:Aged; D001228:Aspergillosis / Q000150:complications / Q000188:drug therapy*; D005260:Female; D015725:Fluconazole / Q000008:administration & dosage*; D006801:Humans; D015552:Injections, Intralesional; D008172:Lung Diseases, Fungal / Q000150:complications / Q000188:drug therapy*; D014397:Tuberculosis, Pulmonary / Q000150:complications
chemical_list: D015725:Fluconazole