Visual recovery in two patients after intravenous methylprednisolone treatment of central retinal artery occlusion secondary to giant-cell arteritis.
Two patients with central retinal artery occlusions secondary to biopsy-proven giant-cell arteritis lost visual acuity to no light perception but recovered to baseline acuity after treatment with intravenous methylprednisolone at a dose of 15 to 30 mg/kg/day. The potential advantages and theoretical basis of early and aggressive treatment with large-dose intravenous corticosteroids in arteritic central retinal artery occlusion are discussed.
Matzkin
D C
DC
Department of Ophthalmology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY 10467.
Slamovits
T L
TL
Sachs
R
R
Burde
R M
RM
D000368:Aged; D001706:Biopsy; D005260:Female; D013700:Giant Cell Arteritis / Q000150:complications*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use*; D015356:Retinal Artery Occlusion / Q000188:drug therapy / Q000209:etiology*; D016896:Treatment Outcome; D014786:Vision Disorders / Q000188:drug therapy* / Q000503:physiopathology; D014792:Visual Acuity
D008775:Methylprednisolone