Leiomyoma of the suprarenal gland in a child with ataxia-telangiectasia.
We report the occurrence of a leiomyoma of the suprarenal gland in a 10-year-old girl with ataxia-telangiectasia (A-T). Muscle cell tumors are very uncommon in this gland as they are in A-T. Possible reasons for developing nonhematologic tumors in this syndrome are reviewed. A defect in DNA repair mechanisms probably favors, in young children, the expression of tumors normally expected in the aged.
Mouchet
F
F
Department of Paediatric Haematology and Oncology, Cliniques Universitaires St Luc, Brussels, Belgium.
Ninane
J
J
Gosseye
S
S
Verellen
C
C
Bonnier
C
C
Evrard
P
P
Vermylen
C
C
Scheiff
J M
JM
Cornu
G
G
D000310:Adrenal Gland Neoplasms / Q000209:etiology / Q000235:genetics / Q000473:pathology*; D001260:Ataxia Telangiectasia / Q000150:complications* / Q000235:genetics; D002648:Child; D007446:Chromosome Inversion; D005260:Female; D006403:Hematologic Tests; D006801:Humans; D007889:Leiomyoma / Q000209:etiology / Q000235:genetics / Q000473:pathology*; D009367:Neoplasm Staging; D014178:Translocation, Genetic