In vitro activity of 79 antimicrobial agents against Corynebacterium group D2.
Corynebacterium group D2 (CGD2) is involved in urinary tract infections in patients with underlying predisposing factors. This microorganism is highly resistant to a number of antimicrobial agents. We tested the activities of 79 antimicrobial agents against CGD2. beta-Lactams, aminoglycosides, and macrolides were ineffective. Fluorinated quinolones showed irregular activities, ofloxacin being the most active one. Doxycycline, rifampin, and mainly glycopeptides (vancomycin and teicoplanin) were the most active antibiotics against CGD2.
García-Rodriguez
J A
JA
Department of Microbiology, Hospital Clinico Universitario, Salamanca, Spain.
García Sánchez
J E
JE
Muñoz Bellido
J L
JL
Nebreda Mayoral
T
T
García Sánchez
E
E
García García
I
I
D042462:4-Quinolones; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003352:Corynebacterium / Q000187:drug effects*; D004352:Drug Resistance, Microbial; D008826:Microbial Sensitivity Tests; D008997:Monobactams / Q000494:pharmacology; D010406:Penicillins / Q000494:pharmacology
D042462:4-Quinolones; D000900:Anti-Bacterial Agents; D008997:Monobactams; D010406:Penicillins