title: Premature vascular calcification in a case of POEMS syndrome.
abstract: A patient with classical POEMS syndrome associated with a myeloproliferative disorder is presented, in whom extensive arterial calcification was seen at an early age in the absence of other predisposing factors. Radiographs also demonstrated several small discrete sclerotic foci elsewhere in the skeleton and areas of new bone formation around the spine which were described in previous cases. Histological studies in this patient demonstrated an osteosclerotic solitary plasmacytoma of bone and Castleman's disease of lymph nodes, both of which have previously been causally associated with POEMS syndrome. In addition, dermal infiltration by mast cells was demonstrated.
authors.affiliation: Department of Diagnostic Radiology, University of South Manchester, U.K.
authors.forename: A
authors.initials: A
authors.lastname: Jackson
authors.forename: I E
authors.initials: IE
authors.lastname: Burton
mesh_terms: D000328:Adult; D002114:Calcinosis / Q000150:complications* / Q000000981:diagnostic imaging; D005871:Castleman Disease / Q000150:complications; D005260:Female; D006801:Humans; D016878:POEMS Syndrome / Q000150:complications* / Q000000981:diagnostic imaging; D011859:Radiography; D014652:Vascular Diseases / Q000150:complications* / Q000000981:diagnostic imaging