[Effect of various infections on the development, course and outcome of glomerulonephritis in children].
Bacteriological and virological tests were made at the disease onset and repeatedly in 100 children (66 boys and 34 girls) aged 2 to 15 years suffering from acute glomerulonephritis. The throat mucus was found to contain streptococci and staphylococci; direct immunofluorescence demonstrated antigens of influenza A1, A3, B virus, of parainfluenza virus, serotypes 1 and 3, of adenovirus and respiratory and syncytial virus; HBs-antigens, specific viral and bacterial antibodies were detected in the blood serum. At the onset of acute glomerulonephritis, 52.5% of the patients were diagnosed to have bacterial infection, 12.5% respiratory viral infection, and 27.5% mixed infection (respiratory viral and bacterial). Besides, 25.5% of the patients showed HBs-antigenemia. HBs-antigenemia and mixed (respiratory viral and bacterial) infection were found to produce an adverse effect on the course and outcome of acute glomerulonephritis. Long-term circulation of some viral antibodies (mostly to parainfluenza-3 antigen) was revealed on repeated studies as was their untoward effect on the outcome of acute glomerulonephritis.
Shparvasser
V V
VV
Kanatbaeva
A B
AB
Ukbaeva
T D
TD
Fokhridina
L I
LI
D000260:Adenoviruses, Human / Q000302:isolation & purification; D000293:Adolescent; D000907:Antibodies, Bacterial / Q000032:analysis; D000914:Antibodies, Viral / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D005260:Female; D005921:Glomerulonephritis / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology; D006515:Hepatitis B virus / Q000276:immunology; D006801:Humans; D008297:Male; D009975:Orthomyxoviridae / Q000276:immunology; D010252:Paramyxoviridae / Q000276:immunology; D013203:Staphylococcal Infections / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D013210:Staphylococcus / Q000276:immunology; D013290:Streptococcal Infections / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D013291:Streptococcus / Q000276:immunology; D014777:Virus Diseases / Q000150:complications* / Q000175:diagnosis / Q000276:immunology
D000907:Antibodies, Bacterial; D000914:Antibodies, Viral
Vliianie nekotorykh infektsiĭ na vozniknovenie, techenie i iskhod ostrogo glomerulonefrita u deteĭ.