Protein catabolic rate calculations in CAPD patients.
Four different approaches to calculating the protein catabolic rate (PCR, in g/kg/day) were investigated in 28 stable continuous ambulatory peritoneal dialysis (CAPD) patients and compared to the dietary protein intake (DPI) from a 3 day diet history. The modified Borah technique is based on the hemodialysis correlation, with the addition of measured effluent protein losses. The Randerson technique is a correlation similar to the Borah hemodialysis correlation, but it was established in a CAPD population. The Teehan technique estimates total nitrogen loss by adding the measured urea nitrogen loss to average values from the literature for protein, amino acid, and non-urea nitrogen losses. The Kjeldahl technique measures total nitrogen loss. All four techniques yielded similar PCR values (0.85-0.92 g/kg/day), none of which was significantly different from the DPI (0.89 g/kg/day). Based on the simplicity of the measurements and calculations, the Randerson technique is recommended for routine monitoring of PCR in CAPD patients.
Keshaviah
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PR
Baxter Clinical Engineering Laboratory, Minneapolis, Minnesota 55404.
Nolph
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D000328:Adult; D000368:Aged; D000596:Amino Acids / Q000097:blood; D001806:Blood Urea Nitrogen; D004044:Dietary Proteins / Q000008:administration & dosage / Q000378:metabolism*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009751:Nutritional Requirements; D010531:Peritoneal Dialysis, Continuous Ambulatory; D011502:Protein-Energy Malnutrition / Q000097:blood*; D012709:Serum Albumin / Q000378:metabolism
D000596:Amino Acids; D004044:Dietary Proteins; D012709:Serum Albumin