title: Correlation of myosin isoforms with anatomical divisions in equine musculus biceps brachii.
abstract: The biceps brachii of horses is subdivided into a lateral and medial head. Electrophoresis of samples from the lateral head revealed three slow-migrating native myosin isoforms, including one that does not correspond to slow myosin isoforms described for other mammalian muscles. In contrast, the medial head contained a single slow isoform. Both the lateral and medial heads contained three fast-migrating isoforms corresponding with the FM-2, FM-3 and FM-4 isoforms reported for other mammalian fast-twitch muscle fibers. Electrophoresis of myosin heavy chains (MHCs) revealed only two MHC bands, one fast-migrating band that comigrates with rat type I MHC and a second slower-migrating band that comigrates with rat type IIa MHC. Quantitation of the histochemical data is correlated with densitometric analysis of MHCs in the medial and lateral heads of biceps brachii and is consistent with previously hypothesized functional specializations of this muscle.
authors.affiliation: Department of Anatomy, College of Veterinary Medicine, Cornell University, Ithaca, N.Y.
authors.forename: J W
authors.initials: JW
authors.lastname: Hermanson
authors.forename: M T
authors.initials: MT
authors.lastname: Hegemann-Monachelli
authors.forename: M J
authors.initials: MJ
authors.lastname: Daaod
authors.forename: W A
authors.initials: WA
authors.lastname: LaFramboise
mesh_terms: D000818:Animals; D003720:Densitometry; D004586:Electrophoresis; D005260:Female; D006651:Histocytochemistry; D006736:Horses / Q000033:anatomy & histology*; D008297:Male; D009132:Muscles / Q000737:chemistry*; D009218:Myosins / Q000032:analysis*
chemical_list: D009218:Myosins