title: Multicentric osteosarcoma. Report of 5 cases.
abstract: Multiple foci of osteosarcoma are found in several pathological conditions: skip metastases, late bone metastases from osteosarcoma, so called metachronous osteosarcoma and multicentric osteosarcoma. The authors describe five cases with multicentric osteosarcoma of the skeleton. These lesions differ from classic osteosarcoma for their clinical and radiographical features. They generally arise in younger patients and are always sclerotic on X-rays and histological evaluation. Our data, as reported in literature, underline the poor prognosis of this disease.
authors.affiliation: Centro Tumori dell'Apparato Locomotore, Istituto Ortopedico Rizzoli, Bologna.
authors.forename: R
authors.initials: R
authors.lastname: Biagini
authors.forename: P
authors.initials: P
authors.lastname: Ruggieri
authors.forename: R
authors.initials: R
authors.lastname: De Cristofaro
authors.forename: P
authors.initials: P
authors.lastname: Torricelli
authors.forename: P
authors.initials: P
authors.lastname: Picci
authors.forename: G
authors.initials: G
authors.lastname: Bacci
mesh_terms: D000293:Adolescent; D001707:Biopsy, Needle; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000473:pathology; D002648:Child; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D012516:Osteosarcoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D011859:Radiography