The transient increase of plasma thrombin-antithrombin III (TAT) complex levels in patients with congenital antithrombin III deficiency during antithrombin III administration is due to extraction of thrombin from fibrin.
Kario
K
K
Department of Internal Medicine, Hyogo Prefectural Awaji Hospital, Japan.
Matsuo
T
T
Kabayashi
H
H
Matsuo
M
M
Yamamoto
K
K
D000293:Adolescent; D000328:Adult; D000990:Antithrombin III / Q000378:metabolism* / Q000627:therapeutic use*; D020152:Antithrombin III Deficiency; D005260:Female; D005337:Fibrin / Q000737:chemistry*; D006801:Humans; D008297:Male; D010447:Peptide Hydrolases / Q000378:metabolism*; D013917:Thrombin / Q000302:isolation & purification*; D013924:Thrombophlebitis / Q000151:congenital / Q000188:drug therapy*; D013997:Time Factors
C046193:antithrombin III-protease complex; D000990:Antithrombin III; D005337:Fibrin; D010447:Peptide Hydrolases; D013917:Thrombin