Painful ejaculation associated with antidepressants in four patients.
BACKGROUND
Painful ejaculation associated with tricyclic antidepressants is rarely reported in the medical literature.


METHODS
Painful ejaculation following the administration of imipramine and clomipramine is described in four patients.


RESULTS
The phenomenon occurred in all patients during the first 3 weeks of treatment and disappeared within several days when the tricyclic dosage was reduced or the medication was withdrawn.


CONCLUSIONS
Painful ejaculation was apparently evoked by tricyclic antidepressant administration. Clinicians should be aware of this underreported side effect.
Aizenberg
D
D
Gehah Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva, Israel.
Zemishlany
Z
Z
Hermesh
H
H
Karp
L
L
Weizman
A
A
D000328:Adult; D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects*; D002997:Clomipramine / Q000009:adverse effects; D003866:Depressive Disorder / Q000188:drug therapy; D004542:Ejaculation / Q000187:drug effects*; D006801:Humans; D007099:Imipramine / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000139:chemically induced*; D016584:Panic Disorder / Q000188:drug therapy
D000929:Antidepressive Agents, Tricyclic; D002997:Clomipramine; D007099:Imipramine