Induction and regulation of interleukin-8 gene expression.
Recent advances in understanding granulocyte elicitation have been made with the discovery and isolation of chemotactic cytokines. There is little doubt that these polypeptides will prove to be important mediators of disease process. Therefore, studies directed at understanding the production and regulation of interleukin-8 will continue to be a fertile area to explore mechanisms of disease processes and therapeutic targets.
Strieter
R M
RM
Department of Pathology, University of Michigan Medical School, Ann Arbor 48109-0602.
Standiford
T
T
Chensue
S W
SW
Kasahara
K
K
Kunkel
S L
SL
D005786:Gene Expression Regulation; D006801:Humans; D007249:Inflammation / Q000378:metabolism; D016209:Interleukin-8 / Q000096:biosynthesis / Q000235:genetics*; D007962:Leukocytes / Q000378:metabolism
D016209:Interleukin-8