title: Effects of naloxone and naltrexone on receptive and proceptive behaviors in female rats.
abstract: The sexual receptive and proceptive behaviors induced by opiate antagonists, naloxone and naltrexone in estrogen-primed ovariectomized rats were observed under the presence of sexually active males. The females were treated intraperitoneally with naloxone or naltrexone at doses ranging from 0.5 to 4.0 mg/kg and the sexual behavior of females was tested before and after the injection of drug. The results obtained suggest that the opiate antagonists play a role in the regulation of lordosis behavior, but not proceptive behavior in female rats.
authors.affiliation: Department of Laboratory Animal Science, Nippon Veterinary and Animal Science University, Tokyo, Japan.
authors.forename: T R
authors.initials: TR
authors.lastname: Saito
authors.forename: S
authors.initials: S
authors.lastname: Aoki
authors.forename: R
authors.initials: R
authors.lastname: Hokao
authors.forename: H
authors.initials: H
authors.lastname: Amao
authors.forename: Y
authors.initials: Y
authors.lastname: Wakafuji
authors.forename: M
authors.initials: M
authors.lastname: Sugiyama
authors.forename: K W
authors.initials: KW
authors.lastname: Takahashi
mesh_terms: D000818:Animals; D005260:Female; D009270:Naloxone / Q000494:pharmacology*; D009271:Naltrexone / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D013268:Stimulation, Chemical
chemical_list: D009270:Naloxone; D009271:Naltrexone