Antibody affinity and protection in virus infections.
Affinity of viral antibodies matures slowly after primary virus infections. Recent investigations with human sera and mouse monoclonal antibodies have provided the first evidence for a role of antibody affinity in the pathogenesis of chronic virus infections. More detailed studies are necessary before the rules and exceptions of this phenomenon are revealed.
Salmi
A A
AA
University of Turku, Finland.
D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D000915:Antibody Affinity; D006801:Humans; D007108:Immune Tolerance; D051379:Mice; D014777:Virus Diseases / Q000276:immunology*
D000914:Antibodies, Viral