Xanthogranulomatous cholecystitis associated with gallbladder adenocarcinoma. A clinicopathological study of 5 cases.
The simultaneous presence of xanthogranulomatous cholecystitis and adenocarcinoma of the gallbladder has rarely been reported. A review of 53 cases of gallbladder adenocarcinoma in a 15-year period revealed 5 cases in which a concomitant diffuse xanthogranulomatous disease was observed. Clinical and pathologic features of these cases are commented and the diagnostic importance stressed. Both inflammatory and neoplastic components were closely mixed in 3 cases, thus making a prompt diagnosis difficult. Etiologic factors implicated in the development of both entities are considered.
Lopez
J I
JI
Departamento de Anatomia Patologica, Hospital Civil de Bilbao, Facultad de Medicina y Odontologia, Universidad del Pais Vasco/EHU, Spain.
Elizalde
J M
JM
Calvo
M A
MA
D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology; D000368:Aged; D002764:Cholecystitis / Q000150:complications* / Q000473:pathology; D005260:Female; D005706:Gallbladder Neoplasms / Q000150:complications* / Q000473:pathology; D006099:Granuloma / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D014973:Xanthomatosis / Q000150:complications* / Q000473:pathology