Histopathological study of porcine gastric mucosa with and without a spiral bacterium ("Gastrospirillum suis").
Tightly spiralled bacteria ("Gastrospirillum suis") were seen in the pyloric mucosa of the stomach of 13 (10.8%) of 120 pigs that appeared clinically healthy at slaughter and in the fundic mucosa of three (5.0%) out of 60 pigs. The spiral organism could not be cultured from any pig. Chronic gastritis was observed in the pyloric mucosa of 53 (44.2%) of 120 pigs and in the fundic mucosa of 7 (11.7%) of 60 pigs. The 13 pigs with spiral bacteria in the pyloric region comprised one animal (7.7%) with normal pyloric mucosa, two (15.4%) with "borderline gastritis", and 10 (76.9%) with chronic gastritis--in one instance accompanied by signs of activity (numerous polymorphonuclear cells). The three pigs with spiral bacteria in the fundic mucosa comprised two animals with a normal fundic region and one with "borderline gastritis". The presence of the spiral bacterium was significantly associated with pyloric gastritis (p = 0.013) and with numbers of lymphoid follicles (p = 0.014).
Mendes
E N
EN
Laboratory of Research in Bacteriology, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Queiroz
D M
DM
Rocha
G A
GA
Nogueira
A M
AM
Carvalho
A C
AC
Lage
A P
AP
Barbosa
A J
AJ
D000818:Animals; D002908:Chronic Disease; D005260:Female; D005748:Gastric Fundus / Q000382:microbiology / Q000473:pathology; D005753:Gastric Mucosa / Q000382:microbiology* / Q000473:pathology; D005756:Gastritis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary; D016480:Helicobacter pylori / Q000254:growth & development / Q000302:isolation & purification*; D008297:Male; D011708:Pylorus / Q000382:microbiology / Q000473:pathology; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology / Q000473:pathology