Bacterial vaginosis and its implication in preterm labor and premature rupture of membranes. A review of the literature.
Preterm delivery continues to occur in 5% to 10% of all births, with a perinatal mortality rate between 50% and 80%. In recent years, the role of infection with lower genital tract organisms in precipitating preterm labor/delivery and premature rupture of membranes has come under considerable study. This article reviews the mechanisms by which infection may play a role in these problems, with a specific focus on bacterial vaginosis. Clinical management issues are addressed, including screening of prenatal patients, diagnostic criteria, and treatment possibilities.
Reynolds
H D
HD
Yale University School of Nursing, New Haven, CT 06536-0740.
D002849:Chromatography, Gas / Q000592:standards; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D007752:Obstetric Labor, Premature / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D011247:Pregnancy; D012307:Risk Factors; D012680:Sensitivity and Specificity; D016585:Vaginosis, Bacterial / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology