Derivatized beta-cyclodextrins combined with high field NMR for enantiomer analysis: application to ICI 185,282 (5(Z)-7- ([2RS,4RS,5SR]-4-o-hydroxyphenyl-2-trifluoromethyl-1,3-dioxan-5-yl) heptenoic acid).
Taylor
A
A
ICI Pharmaceuticals, Pharmaceutical Department, Macclesfield, Cheshire, UK.
Williams
D A
DA
Wilson
I D
ID
D003505:Cyclodextrins; D004146:Dioxanes / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D013237:Stereoisomerism
D003505:Cyclodextrins; D004146:Dioxanes; C059061:ICI 185282