title: Left ventricular thrombus in a 2-year-old boy with cardiomyopathy: lysis with recombinant tissue-type plasminogen activator.
abstract: A 2-year-old boy with cardiomyopathy and clinical signs of cardiac failure presented with an echodense structure in the left ventricle. This structure was seen from different echocardiographic views adjacent to a hypokinetic area of the apex and lateral free wall. It was different in texture and motion from the underlying myocardium and thus met the diagnostic criteria of a left ventricular thrombus. This thrombus protruded into the cavum and was partly mobile. In view of a high embolic risk, thrombolytic therapy with recombinant tissue plasminogen activator was started. The thrombus resolved within 72 h without any embolic or bleeding complications. No recurrence of the thrombus was observed during a 3-month follow up period.
authors.affiliation: Department of Paediatrics, Heinrich Heine Universität, Düsseldorf, Federal Republic of Germany.
authors.forename: O N
authors.initials: ON
authors.lastname: Krogmann
authors.forename: R
authors.initials: R
authors.lastname: von Kries
authors.forename: S
authors.initials: S
authors.lastname: Rammos
authors.forename: H H
authors.initials: HH
authors.lastname: Kramer
authors.forename: M
authors.initials: M
authors.lastname: Bourgeois
mesh_terms: D009202:Cardiomyopathies / Q000150:complications*; D002675:Child, Preschool; D004452:Echocardiography; D006331:Heart Diseases / Q000188:drug therapy*; D006801:Humans; D008297:Male; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000150:complications* / Q000188:drug therapy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
chemical_list: D010959:Tissue Plasminogen Activator