T-cell receptor and T-cell-resistant virus variants.
Analysis of the T-cell receptor has revealed the molecular basis of antigen recognition by T cells specific for viral antigens. Studies using T-cell receptor transgenic mice have provided evidence for clonal deletion of virus-specific T cells in persistently infected hosts and for selection of T-cell-resistant virus variants in vivo.
Yanagi
Y
Y
Scripps Research Institute, La Jolla, California.
D000818:Animals; D000956:Antigens, Viral / Q000276:immunology; D015329:Gene Rearrangement, T-Lymphocyte; D007111:Immunity, Cellular; D008285:Major Histocompatibility Complex / Q000276:immunology; D051379:Mice; D011948:Receptors, Antigen, T-Cell / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*; D014780:Viruses / Q000276:immunology*
D000956:Antigens, Viral; D011948:Receptors, Antigen, T-Cell