Orbital tumor in an infant with acute monocytic leukemia associated with chromosome 5q-,t(9p-11q+),11p+.
We examined an 8-month-old infant with left proptosis, chemosis and orbital mass. A computed tomographic scan revealed a left orbital tumor. An anorectal nodule was also found. Results of the hematologic study showed poorly differentiated acute monocytic leukemia (M5 according to the French-American-British classification). Chromosomal analysis disclosed 46, XX,5q-,t(9p-;11q+),11p+. We believe that our patient represents a rare case of orbital tumor in acute monocytic leukemia associated with chromosomal abnormalities.
Hayasaka
S
S
Department of Ophthalmology, Shimane Medical University, Izumo, Japan.
Noda
S
S
Ishikura
S
S
Setogawa
T
T
Mori
C
C
D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D002895:Chromosomes, Human, Pair 5; D005260:Female; D006801:Humans; D007223:Infant; D007621:Karyotyping; D007948:Leukemia, Monocytic, Acute / Q000235:genetics*; D009918:Orbital Neoplasms / Q000235:genetics*; D014178:Translocation, Genetic