title: [Pelvic recurrences after curative surgery for rectal cancer].
abstract: This report updates an experience with local recurrences of rectal cancer after curative surgery. Overall 13 year period (1976-1988) 254 patients were operated on in the II Surgical Clinic of Parma University for rectal cancer. Only 122 patients who underwent potentially curative resection were examined. Approximate recurrence rates according to patients age, site, type and stage of primitive tumour, tumour complications and surgical procedures were evaluated. The overall local failure rate was 17.2% with 12 patients having local failure alone and 9 patients having concurrent local failure and distant metastasis. Local failure occurred predominantly in tumour bed, involving the anastomosis in 2 cases. Relapse developed primarily at colo-rectal anastomosis in only 1 patients, 20% of recurrences were diagnosed within the first postoperative year; 65% within the second and 90% within the third. Stage of primary tumour was the most predictive factor for eventual relapse. Minute foci of tumour not encompassed by the first operation led to local recurrences in most of the cases, but relapses were independent of operative procedures adopted. The authors conclude that surgery, even if correctly performed, is not sufficient to prevent the risk of local recurrence of rectal cancer. They believe that routine adjuvant radiation therapy after surgical treatment of rectal cancer should improve survival rate.
authors.affiliation: Istituto di II Clinica Chirurgica Generale e Terapia Chirurgica dell'Università di Parma.
authors.forename: A
authors.initials: A
authors.lastname: Peracchia
authors.forename: L
authors.initials: L
authors.lastname: Sarli
authors.forename: N
authors.initials: N
authors.lastname: Pietra
authors.forename: F
authors.initials: F
authors.lastname: Carreras
authors.forename: E
authors.initials: E
authors.lastname: Longinotti
authors.forename: M
authors.initials: M
authors.lastname: Gafà
mesh_terms: D000367:Age Factors; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008207:Lymphatic Metastasis; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology; D009367:Neoplasm Staging; D010386:Pelvic Neoplasms / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology; D012004:Rectal Neoplasms / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology / Q000601:surgery; D012007:Rectum / Q000601:surgery; D012737:Sex Factors; D013997:Time Factors
vernacular_title: Recidive pelviche dopo chirurgia curativa per cancro del retto.