[The quality control of a photoprotector bag against ultraviolet light].
The action of light on parenteral nutritional solutions may affect the stability of many of their ingredients. The aim of this study is to perform quality controls on a commercial photoprotective bag by quantifying the degradation of riboflavin in isotonic saline solution during forty-eight hours. Thirty solutions were prepared using 5 mg of riboflavin in 500 ml of saline solution. These were divided into three batches; one not protected from the light, one in a black bag and the third in a commercial bag. Samples were taken at 0 and 48 hours, and were analyzed by spectrophotometry. Solutions were prepared using 1.75 mg of riboflavin in 500 ml of saline solution. The same method was followed, and the samples were analyzed by fluorometry. The results were analyzed using the Student t test. The black bag was seen to be superior to the other two as a protector against ultraviolet light. There were no significant differences between the commercial bag and the non-protective bag.
Piña Vera
M J
MJ
Servicio de Farmacia, Hospital Universitario Virgen del Rocío, Sevilla.
Carvajal Gragera
E
E
Lluch Colomer
A
A
Atienza Fernández
M
M
D005069:Evaluation Studies as Topic; D007552:Isotonic Solutions; D010288:Parenteral Nutrition / Q000295:instrumentation*; D011786:Quality Control; D011835:Radiation Protection / Q000295:instrumentation*; D012256:Riboflavin / Q000032:analysis / Q000528:radiation effects; D013050:Spectrometry, Fluorescence; D013056:Spectrophotometry, Ultraviolet; D013997:Time Factors; D014466:Ultraviolet Rays
D007552:Isotonic Solutions; D012256:Riboflavin
Control de calidad de una bolsa fotoprotectora de luz ultravioleta.