title: NADH oxidase and fumarate reductase of Ancylostoma ceylanicum.
abstract: Ancylostoma ceylanicum, the hookworm parasite of cat, dog and man, was found to contain NADH and/or NADPH oxidase as well as fumarate reductase activities. Both the enzyme systems were predominantly located in the membranes of mitochondrial-rich preparations. The membranes also exhibited the presence of a reduced pyridine nucleotide transhydrogenase activity which transferred hydrogen from NADPH to NAD. Amongst respiratory inhibitors, rotenone (Site I inhibitor) markedly depressed both NADH oxidase and fumarate reductase while others, namely antimycin-A, KCN and azide, had a lesser effect.
authors.affiliation: Division of Biochemistry, Central Drug Research Institute, Lucknow, India.
authors.forename: N
authors.initials: N
authors.lastname: Goyal
authors.forename: S
authors.initials: S
authors.lastname: Gupta
authors.forename: J C
authors.initials: JC
authors.lastname: Katiyar
authors.forename: V M
authors.initials: VM
authors.lastname: Srivastava
mesh_terms: D000722:Ancylostoma / Q000201:enzymology*; D000818:Animals; D008928:Mitochondria / Q000201:enzymology; D009097:Multienzyme Complexes / Q000378:metabolism*; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism*; D013385:Succinate Dehydrogenase / Q000378:metabolism*
chemical_list: D009097:Multienzyme Complexes; D013385:Succinate Dehydrogenase; C023107:NADH oxidase; D009247:NADH, NADPH Oxidoreductases