title: [Evaluation of the prevalence of side effects of phenobarbital in patients in the Champagne-Ardenne region].
abstract: Side effects were compared in 454 patients under phenobarbital and in 133 patients under other antiepileptic agents. Prevalence of adverse effects was 12% and 4% in these two groups, respectively. The fairly low prevalence of untoward reactions to phenobarbital in this study as compared with previously published reports is due to the methodology used. Despite unquestionable drawbacks, especially in patients above 50 years of age at first use, phenobarbital is a valuable therapeutic alternative in some cases.
authors.affiliation: Institut National de la Santé et de la Recherche Médicale, Unité 169, Villejuif, France.
authors.forename: N
authors.initials: N
authors.lastname: Delasnerie-Lauprêtre
authors.forename: J C
authors.initials: JC
authors.lastname: Turpin
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D004827:Epilepsy / Q000188:drug therapy*; D005260:Female; D005602:France; D005891:Gingivitis / Q000139:chemically induced; D006801:Humans; D008297:Male; D008875:Middle Aged; D010634:Phenobarbital / Q000009:adverse effects* / Q000627:therapeutic use; D015995:Prevalence; D012189:Retrospective Studies; D012216:Rheumatic Diseases / Q000139:chemically induced* / Q000453:epidemiology; D012307:Risk Factors; D012894:Sleep Stages
chemical_list: D000927:Anticonvulsants; D010634:Phenobarbital
vernacular_title: Evaluation de la fréquence des effets secondaires du phénobarbital dans une population de malades suivis en Champagne-Ardenne.