title: Cortical blindness in postpartum preeclampsia progressing to eclampsia: case report.
abstract: A 23-year-old woman who had an uneventful prenatal course and normal delivery developed severe, generalized headache and blurred vision on postpartum day four. The patient was noted to have generalized hyperreflexia and sustained ankle clonus. The blood pressure was 170/100 mm Hg, there was no edema, and the urine showed trace proteinuria. The visual disturbance rapidly progressed to complete blindness with preserved pupillary reactions. The patient then had a generalized tonic-clonic seizure lasting about one minute. Treatment was initiated with intravenous diazepam and phenytoin, and there was no recurrence of seizure activity. Vision returned to normal and the patient made a complete recovery. This case is presented to demonstrate progressive postpartum pre-eclampsia and the importance of early recognition and treatment. Pathophysiologic mechanisms and treatment options are discussed.
authors.affiliation: Department of Neurology, Mount Sinai School of Medicine (CUNY), New York, NY 10029.
authors.forename: D
authors.initials: D
authors.lastname: Mandelkern
authors.forename: A
authors.initials: A
authors.lastname: Burger
mesh_terms: D000328:Adult; D001766:Blindness / Q000209:etiology*; D004461:Eclampsia / Q000150:complications*; D005260:Female; D006801:Humans; D011225:Pre-Eclampsia / Q000150:complications; D011247:Pregnancy; D011644:Puerperal Disorders / Q000150:complications*; D012640:Seizures / Q000150:complications; D013997:Time Factors