Cytogenetics of six follicular thyroid adenomas including a case report of an oxyphil variant with t(8;14)(q13;q24.1).
Cytogenetic analyses were performed on six follicular thyroid adenomas. Five had normal karyotypes and one, an oxyphil adenoma, had a t(8;14)(q13;q24.1). This patient also had a history of pleomorphic adenoma of the parotid gland. This clonal abnormality may suggest a primary genetic lesion in this patient who had two different benign neoplasms.
Herrmann
M A
MA
Cytogenetics Laboratory, Mayo Clinic, Rochester, MN 55905.
Hay
I D
ID
Bartelt
D H
DH
Spurbeck
J L
JL
Dahl
R J
RJ
Grant
C S
CS
Jenkins
R B
RB
D000236:Adenoma / Q000235:genetics*; D000368:Aged; D002883:Chromosomes, Human, Pair 14; D002898:Chromosomes, Human, Pair 8; D005260:Female; D006801:Humans; D016609:Neoplasms, Second Primary / Q000235:genetics; D010307:Parotid Neoplasms / Q000235:genetics; D013964:Thyroid Neoplasms / Q000235:genetics*; D014178:Translocation, Genetic