title: The effect of the Angelchik prosthesis on esophageal and gastric function.
abstract: The effects of the Angelchik prosthesis on esophageal and gastric function were investigated in 17 patients (11 men and six women; median age, 57 years; age range, 36 to 88 years) who underwent surgery for treatment of gastroesophageal reflux disease. All patients demonstrated unequivocal reflux, either at endoscopy or 24-hour pH testing. There was a significant increase in lower esophageal sphincter pressure after surgery, and no patient demonstrated abnormal reflux on pH testing. Gastric emptying of liquids and solids was not altered by surgery. Six months after surgery, all symptoms except dysphagia had significantly improved. Thirty-three months after surgery, six patients described symptoms as severe as or worse than those before surgery. Four patients had the prosthesis removed, two because of dysphagia alone, one because of reflux and dysphagia, and one because of flatulence and bloating. The patients who required removal of the prosthesis because of dysphagia had gross delay of esophageal emptying. We conclude that the Angelchik prosthesis is an effective antireflux device, but it interferes with esophageal function in some patients, requiring removal of the prosthesis. We think the rate of removal of the prosthesis is too high for its routine use in the treatment of gastroesophageal reflux disease.
authors.affiliation: Department of Surgery, Royal Adelaide Hospital, Australia.
authors.forename: G J
authors.initials: GJ
authors.lastname: Maddern
authors.forename: J C
authors.initials: JC
authors.lastname: Myers
authors.forename: N
authors.initials: N
authors.lastname: McIntosh
authors.forename: F H
authors.initials: FH
authors.lastname: Bridgewater
authors.forename: G G
authors.initials: GG
authors.lastname: Jamieson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003680:Deglutition Disorders / Q000209:etiology; D004945:Esophagoscopy; D004947:Esophagus / Q000502:physiology* / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D005746:Gastric Emptying; D005764:Gastroesophageal Reflux / Q000601:surgery*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008365:Manometry; D008875:Middle Aged; D019736:Prostheses and Implants / Q000009:adverse effects; D011474:Prosthesis Design