A review of forty-five years study of Hiroshima and Nagasaki atomic bomb survivors. Chromosome abnormality in early entrants.
A preliminary study was performed to estimate radiation dose in 10 individuals who had entered Hiroshima city one day after the explosion and worked around the hypocenter area for a week. The numbers of cells with chromosome aberrations differed in each subject, ranging from one to 18 (median: 11 abnormalities) in 500 metaphases of lymphocytes cultured for 48 hours with Phytohemagglutinin. Five individuals had more than 1.6 percent stable type aberrations and were estimated to have been exposed to 6-13 rad. The other five individuals and the controls were estimated to be less than two rad.
Kamada
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Department of Hematology, Hiroshima University, Japan.
D000368:Aged; D002869:Chromosome Aberrations; D006801:Humans; D007564:Japan; D008875:Middle Aged; D009689:Nuclear Warfare; D011831:Radiation Genetics; D013997:Time Factors