title: Magnetic resonance imaging of body fat of athletes compared with controls, and the oxidative metabolism of estradiol.
abstract: The extent of 2-hydroxylation of estradiol (E2), which yields a non-estrogenic metabolite (2-OHE1), increased significantly with decreasing subcutaneous fat (ScF)/total volume percent (TV%) and total fat (TF)/TV% evaluated by magnetic resonance imaging (MRI) for five athletes during low- and high-intensity training, and four controls. The increase in 2-hydroxylation with decreasing adiposity was associated with anovulation and amenorrhea among the athletes.
authors.affiliation: Harvard Center for Population Studies, Cambridge, MA 02138.
authors.forename: R E
authors.initials: RE
authors.lastname: Frisch
authors.forename: R
authors.initials: R
authors.lastname: Snow
authors.forename: E L
authors.initials: EL
authors.lastname: Gerard
authors.forename: L
authors.initials: L
authors.lastname: Johnson
authors.forename: D
authors.initials: D
authors.lastname: Kennedy
authors.forename: R
authors.initials: R
authors.lastname: Barbieri
authors.forename: B R
authors.initials: BR
authors.lastname: Rosen
mesh_terms: D000273:Adipose Tissue / Q000033:anatomy & histology* / Q000378:metabolism; D000328:Adult; D001835:Body Weight; D004958:Estradiol / Q000378:metabolism*; D015444:Exercise; D005260:Female; D006801:Humans; D006900:Hydroxylation; D008279:Magnetic Resonance Imaging; D012016:Reference Values; D013177:Sports
chemical_list: D004958:Estradiol