title: The significance of the microcyst response: a review.
abstract: Epithelial microcysts have been identified as a significant corneal response to contact lens wear. The characteristics of the microcyst response are outlined and factors which influence the level of microcysts including lens type, oxygen transmissibility (Dk/L), and wear schedule are discussed. Understanding of the morphology, pathology, etiology, and clinical significance of microcysts is currently incomplete and various hypotheses are discussed.
authors.affiliation: Cornea and Contact Lens Research Unit, School of Optometry, University of New South Wales, Sydney, Australia.
authors.forename: B A
authors.initials: BA
authors.lastname: Holden
authors.forename: D F
authors.initials: DF
authors.lastname: Sweeney
mesh_terms: D003261:Contact Lenses / Q000009:adverse effects*; D003316:Corneal Diseases / Q000209:etiology* / Q000473:pathology; D003560:Cysts / Q000209:etiology* / Q000473:pathology; D006801:Humans; D010101:Oxygen Consumption; D013997:Time Factors