[Hepatitis B infection and primary glomerulonephritis in children].
Out of 165 children presenting with renal pathology, HBV-infection was detected by RIA in 69.7% of children suffering from glomerulonephritis and in 30.8% of children with pyelonephritis. The infection manifested by the carriage of HBs-antigen and persistent hepatitis. Unlike the control group (without HBv-infection), in patients with HBv-infection, glomerulonephritis was characterized by the development of a prognostically unfavourable mixed form there of in children under 7 years, by rare cases of the onset of a complete remission consequent to immunosuppressive therapy, a decline of the level of serum IgG and the T lymphocyte count, a reduction of the helper/suppressor ratio to 1.21 at the expense of a decrease of the number of helpers, and a higher amount of lymphocytes expressing receptors to IL-2.
Naumova
V I
VI
Ilamanov
M
M
Ivanov
V G
VG
Ni
A N
AN
D015415:Biomarkers / Q000097:blood; D002648:Child; D002675:Child, Preschool; D005260:Female; D006509:Hepatitis B / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D006510:Hepatitis B Antibodies / Q000032:analysis / Q000276:immunology; D006512:Hepatitis B Core Antigens / Q000032:analysis / Q000276:immunology; D006514:Hepatitis B Surface Antigens / Q000032:analysis / Q000276:immunology; D006513:Hepatitis B e Antigens / Q000032:analysis / Q000276:immunology; D006515:Hepatitis B virus / Q000276:immunology / Q000472:pathogenicity; D006801:Humans; D007223:Infant; D008297:Male; D009402:Nephrosis, Lipoid / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology
D015415:Biomarkers; D006510:Hepatitis B Antibodies; D006512:Hepatitis B Core Antigens; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens
HB-virusnaia infektsiia i pervichnyĭ glomerulonefrit u deteĭ.