title: The postnatal development of the oscillatory potentials of the electroretinogram. III. Scotopic characteristics.
abstract: The postnatal development of the oscillatory potentials (OPs) of the rat electroretinogram (ERG) was studied during more extreme scotopic conditions. Enhancement of scotopic conditions did not facilitate any earlier appearance of the OPs, including the later ones, compared to previously studied less scotopic conditions. The oscillatory activity appeared at Days 12 to 15, and increased rapidly up to Day 17, which coincided with the major period of development of the photoreceptors. After the physiological opening of the eyelids there was a decline of the OPs. We propose that the decline of the oscillatory activity induced during more extreme scotopic conditions is related to early cell death in the distal retina and/or to developmental neuronal plasticity in the proximal retina.
authors.affiliation: Department of Ophthalmology, Karolinska Institute/Huddinge University Hospital, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: el Azazi
authors.forename: L
authors.initials: L
authors.lastname: Wachtmeister
mesh_terms: D000818:Animals; D003623:Dark Adaptation; D004596:Electroretinography; D009991:Oscillometry; D051381:Rats; D011919:Rats, Inbred Strains; D012160:Retina / Q000254:growth & development / Q000503:physiopathology*