Clinical results with the Biocor porcine bioprosthesis.
In order to evaluate our clinical results with the use of the Biocor prosthesis, a total of 1,101 patients were studied. Follow-up was from 1 to 96 months (mean 48); cumulative follow-up in the aortic group (385 patients) was 1,230 patient years and in the mitral group (716 patients) 3,018 patient years. Mitral patients had 102 late complications (14.24%), and aortic patients had 51 (13.2%). A total of 220 patients were under 20 years of age (176 mitral, 44 aortic). Intrinsic valve failure in this subgroup was found in 43% of mitral patients and 29% of aortic patients. Prosthetic endocarditis was more frequent in the aortic group (45%) than in the mitral group (29.9%). Sixty-two patients were reoperated, with a hospital mortality of 12.6%. Reoperation was more frequent in the mitral group and in patients under 20 years of age. The actuarial curve free mortality related to the bioprosthesis was 97.1% (32 patients). At the 8-year follow-up, 96.9% of the aortic versus 95.2% of the mitral group were free of valve dysfunction, and the majority were in Classes I or II of the New York Heart Association (NYHA) classification. The incidence of reoperation, although significant, is acceptable, especially since the bioprosthesis offers a safer alternative than mechanical prostheses followed for similar periods. Analysis of our results suggests the need for continued research for an ideal bioprosthesis.
Vrandecic
M O
MO
Santa Casa de Miserìcórdia de Belo Horizonte, Brazil.
Gontijo Filho
B
B
Paula e Silva
J A
JA
Fantini
F A
FA
Barbosa
J T
JT
São José
M C
MC
Dos Santos Pinto
C A
CA
Vieira
G L
GL
Oliveira
H G
HG
Rabelo
S
S
D000206:Actuarial Analysis; D000328:Adult; D001021:Aortic Valve; D001705:Bioprosthesis; D002648:Child; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000401:mortality*; D017052:Hospital Mortality; D006801:Humans; D015994:Incidence; D008943:Mitral Valve; D011183:Postoperative Complications / Q000401:mortality; D011474:Prosthesis Design; D016459:Prosthesis-Related Infections / Q000401:mortality; D012086:Reoperation; D013997:Time Factors