Pure 4p trisomy due to a de novo 4q;22p dicentric translocated chromosome karyotype 46,XX,-22,+t(4;22)(q1200;p13).
A de novo t(4;22)(q1200;p13) is reported in a girl with a florid 4p trisomy phenotype. The abnormal chromosome was identified by high resolution, C-bands and confirmed by 5-BrdU as de novo dicentric translocated chromosome.
de Almeida
J C
JC
Unidade de Citogenética Humana, Instituto de Biofísica Carlos Chagas F. UFRJ, Rio de Janeiro, Brazil.
Reis
D F
DF
Llerena Júnior
J C
JC
D000293:Adolescent; D002894:Chromosomes, Human, Pair 4; D005260:Female; D006801:Humans; D007621:Karyotyping; D014178:Translocation, Genetic / Q000235:genetics*; D014314:Trisomy