Localization of outer surface proteins A and B in both the outer membrane and intracellular compartments of Borrelia burgdorferi.
Borrelia burgdorferi B31 with and without outer membranes contained nearly identical amounts of outer surface proteins A and B. The majority of each immunogen also was localized intracellularly by immunocryoultramicrotomy. These results are inconsistent with the widely held belief that outer surface proteins A and B are exclusively outer membrane proteins.
Brusca
J S
JS
Department of Microbiology, Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas 75235.
McDowall
A W
AW
Norgard
M V
MV
Radolf
J D
JD
D001425:Bacterial Outer Membrane Proteins / Q000032:analysis*; D015748:Borrelia burgdorferi Group / Q000737:chemistry* / Q000648:ultrastructure; D002462:Cell Membrane / Q000737:chemistry / Q000648:ultrastructure; D007150:Immunohistochemistry; D008854:Microscopy, Electron
D001425:Bacterial Outer Membrane Proteins