title: Cardioembolic stroke. Primary and secondary prevention.
abstract: Modern prospective trials have recently shown that warfarin prescribed to produce less anticoagulant effect than was customary in the past reduces cardioembolic stroke by up to 80% in patients with nonvalvular atrial fibrillation. These results represent a major advance in stroke prevention. The effectiveness of antithrombotic treatment in other settings in which there is risk of cardioembolism is less well established but likely to be substantial.
authors.affiliation: Department of Neurology, Hennepin County Medical Center, Minneapolis, MN 55415.
authors.forename: D C
authors.initials: DC
authors.lastname: Anderson
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000150:complications; D002561:Cerebrovascular Disorders / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D011322:Primary Prevention / Q000379:methods*; D012307:Risk Factors
chemical_list: D000925:Anticoagulants