title: Silicone injection management of diabetic foot ulcers: a possible model for prevention of pressure ulcers.
abstract: Long-term clinical and histologic findings with injectable fluid silicone to reduce mechanical forces over plantar skin are described. The fluid induces a relatively stable soft tissue prosthesis between skin and bone, reducing the frequency of insensitive ulcer recurrence in the foot. On the basis of these favorable findings, studies are warranted to determine the fluid's efficacy in prevention of pressure ulcers.
authors.forename: S W
authors.initials: SW
authors.lastname: Balkin
authors.forename: L
authors.initials: L
authors.lastname: Kaplan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003929:Diabetic Neuropathies / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D016523:Foot Ulcer / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012828:Silicones / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D012828:Silicones