Prediction of gas chromatographic relative retention times of anabolic steroids.
The prediction of gas chromatographic relative retention times (RRTs) of anabolic steroids, used in the doping control of athletes, was performed by a quantitative structure-retention relationship (QSRR) and multiple linear regression analysis study. A nine-variable model was generated with a multiple correlation coefficient R = 0.991 and relative standard error of less than 3%. Preliminary results indicated that the application of the model, especially in the prediction of RRTs of metabolites of the anabolic steroids, will be helpful.
Georgakopoulos
C G
CG
Doping Control Laboratory, Olympic Athletic Center of Athens, Greece.
Tsika
O G
OG
Kiburis
J C
JC
Jurs
P C
PC
D045930:Anabolic Agents / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D011237:Predictive Value of Tests; D012044:Regression Analysis
D045930:Anabolic Agents