The expression of a deafferentation syndrome in the Sprague-Dawley rat: effects of frontoparietal cortical lesions.
Forelimb sensorimotor (SMI) cortical lesions in the rat have been found to suppress a deafferentation syndrome which follows C5-T2 ganglionectomy/avulsion whether the cortical lesions were made prior to, or several days after, the dorsal root lesions. None of the 6 rats with only frontoparietal lesions developed a deafferentation syndrome. These results may be influenced by the presence of a sensorimotor amalgam in the parietal cortex of the rat.
Ovelmen-Levitt
Janice
J
Division of Neurosurgery, Duke University Medical Center, Durham, NC 27710 U.S.A.
Young
Jacob N
JN
Rossitch
Eugene
E
Nashold
Blaine S
BS
D000344:Afferent Pathways / Q000502:physiology; D000818:Animals; D001522:Behavior, Animal / Q000502:physiology; D005260:Female; D005625:Frontal Lobe / Q000502:physiology* / Q000601:surgery; D010146:Pain / Q000209:etiology / Q000503:physiopathology*; D010296:Parietal Lobe / Q000502:physiology* / Q000601:surgery; D051381:Rats; D011919:Rats, Inbred Strains; D013577:Syndrome