[A comparison of the value of magnetic resonance tomography and computed tomography in Nelson syndrome patients].
The hypophyses of 13 patients with Nelson syndrome following bilateral adrenalectomy were examined by MRI and CT. Diffuse enlargement of the hypophysis was demonstrated in 8 patients by CT and in 9 by MRI. Compared with CT, MRI provides better demonstration of tumour development, such as abnormal convexity of the cranial margin of the hypophysis (MRI 4/13, CT 1/13), displacement of the infundibulum (MRI 4/13, CT 0/13) or optic chiasm (MRI 2/13, CT 0/13). MRI also provides diagnostically important differentiation between scar tissue and recurrence of tumour following hypophysectomy (MRI 1/3, CT 0/3) and more accurate demonstration of infiltration of the cavernous sinus (MRI 4/13, CT 2/13). CT is superior only in showing the floor of the sella. MRI is the method of choice for imaging in cases of Nelson syndrome.
Kersjes
W
W
Institut für Klinische Strahlenkunde, Universität Mainz.
Allmendinger
S
S
Stiebler
H
H
Christ
F
F
Bockisch
A
A
Klingmüller
D
D
D000315:Adrenalectomy; D000328:Adult; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007016:Hypophysectomy; D007479:Iopamidol; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods; D008297:Male; D008875:Middle Aged; D009347:Nelson Syndrome / Q000175:diagnosis*; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D010902:Pituitary Gland / Q000000981:diagnostic imaging / Q000473:pathology; D010911:Pituitary Neoplasms / Q000175:diagnosis; D014057:Tomography, X-Ray Computed / Q000379:methods
D007479:Iopamidol
Vergleich der Wertigkeit von Magnetresonanztomographie und Computertomographie bei Patienten mit Nelson-Syndrom.