title: AIDS and tuberculosis in Spain. A report of 140 cases.
abstract: From January 1984 to October 1990, 140 of 392 (35.7%) patients with the acquired immunodeficiency syndrome (AIDS) were found to have had tuberculosis. One hundred and sixteen were intravenous drug abusers and 16 were homosexual men. Fever, cough, weight loss and generalised lymphadenopathy were common features of their illness. Tuberculin skin tests were negative in 74% and 55% had intraabdominal lymphadenopathy. The chest radiographs showed hilar lymphadenopathy and lower lobe interstitial or alveolar infiltrates, but rarely cavitation. Forty-one of our patients had pulmonary tuberculosis, 38 had extra pulmonary and in 61 it was disseminated. In 80 cases tuberculosis was the presenting feature of AIDS. Tuberculosis usually responded well to chemotherapy.
authors.affiliation: Service of Infectious Diseases, Instituto de Salud Carlos III, Madrid, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Laguna
authors.forename: M
authors.initials: M
authors.lastname: Adrados
authors.forename: F
authors.initials: F
authors.lastname: Díaz
authors.forename: R
authors.initials: R
authors.lastname: Martínez
authors.forename: C
authors.initials: C
authors.lastname: García Aguado
authors.forename: S
authors.initials: S
authors.lastname: Puente
authors.forename: J M
authors.initials: JM
authors.lastname: González Lahoz
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D004359:Drug Therapy, Combination; D004977:Ethambutol / Q000627:therapeutic use; D005260:Female; D006801:Humans; D015994:Incidence; D007538:Isoniazid / Q000627:therapeutic use; D008297:Male; D011446:Prospective Studies; D011718:Pyrazinamide / Q000627:therapeutic use; D012189:Retrospective Studies; D012293:Rifampin / Q000627:therapeutic use; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology; D013307:Streptomycin / Q000627:therapeutic use; D015819:Substance Abuse, Intravenous / Q000150:complications; D014376:Tuberculosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology
chemical_list: D011718:Pyrazinamide; D004977:Ethambutol; D007538:Isoniazid; D012293:Rifampin; D013307:Streptomycin