The effects of tricaine methanesulfonate (MS-222) on plasma nonesterified fatty acids in rainbow trout, Oncorhynchus mykiss.
The effects of tricaine methanesulfonate (MS-222), a commonly used fish anesthetic, on plasma nonesterified fatty acid levels (NEFA) were examined in rainbow trout, Oncorhynchus mykiss. Total NEFA levels declined with increasing duration of exposure to MS-222. Most of the decline in total NEFA was due to decreases in saturated fatty acids (14:0, 16:0 and 18:0). The fatty acid displaying the most rapid response to exposure to MS-222 was 20:5n-3. The lower plasma NEFA levels in anesthetized fish may be explained by depressed lipolysis in the presence of the anesthetic.
Harrington
A J
AJ
Department of Zoology, University of Guelph, Ontario, Canada.
Russell
K A
KA
Singer
T D
TD
Ballantyne
J S
JS
D062365:Aminobenzoates / Q000494:pharmacology*; D000777:Anesthetics / Q000494:pharmacology; D000818:Animals; D005227:Fatty Acids / Q000097:blood / Q000737:chemistry; D005230:Fatty Acids, Nonesterified / Q000097:blood* / Q000737:chemistry; D008066:Lipolysis / Q000187:drug effects; D014337:Trout / Q000378:metabolism*
D062365:Aminobenzoates; D000777:Anesthetics; D005227:Fatty Acids; D005230:Fatty Acids, Nonesterified; C003636:tricaine