title: [A case of prolonged eosinophilic pneumonia with pulmonary emphysema and bronchial asthma diagnosed by open lung biopsy].
abstract: A 65-year-old man was admitted to our hospital complaining of productive cough, dyspnea and stridor. Chest X-ray disclosed overinflation with micronodular infiltrates. Blood examination showed mild eosinophilia and IgE elevation. Pulmonary function test disclosed severe airway obstruction and diffusion capacity impairment. Although clinical improvement was achieved after bronchodilator therapy, laboratory abnormalities continued. Open lung biopsy demonstrated mononuclear cellular and eosinophilic infiltration at alveolar lumen and vessel walls without prominent fibrosis, which was compatible for prolonged eosinophilic pneumonia. From above findings, this case was thought as a prolonged eosinophilic pneumonia combined with pulmonary emphysema and bronchial asthma.
authors.affiliation: Second Department of Internal Medicine, Nara Medical University.
authors.forename: Y
authors.initials: Y
authors.lastname: Koyama
authors.forename: H
authors.initials: H
authors.lastname: Ako
authors.forename: H
authors.initials: H
authors.lastname: Katada
authors.forename: K
authors.initials: K
authors.lastname: Hamada
authors.forename: H
authors.initials: H
authors.lastname: Kasuga
authors.forename: K
authors.initials: K
authors.lastname: Nishikawa
authors.forename: N
authors.initials: N
authors.lastname: Narita
authors.forename: S
authors.initials: S
authors.lastname: Iioka
authors.forename: S
authors.initials: S
authors.lastname: Kitamura
authors.forename: M
authors.initials: M
authors.lastname: Kitagawa
mesh_terms: D000368:Aged; D001249:Asthma / Q000150:complications*; D001706:Biopsy; D001995:Bronchography; D006801:Humans; D008168:Lung / Q000473:pathology*; D008297:Male; D011656:Pulmonary Emphysema / Q000150:complications*; D011657:Pulmonary Eosinophilia / Q000150:complications* / Q000175:diagnosis; D013902:Radiography, Thoracic; D014057:Tomography, X-Ray Computed