Localisation of the gene for Norrie disease to between DXS7 and DXS426 on Xp.
A highly informative microsatellite marker, DXS426, which maps proximal to DXS7 in the interval Xp11.4-Xp11.23, has been used to refine further the localisation of the gene for Norrie disease (NDP). The results from a multiply informative crossover localize the NDP gene proximal to DXS7. In conjunction with information from 2 NDP patients who have a deletion for DXS7 but not for DSX426, our data indicate that the NDP gene lies between DXS7 and DXS426 on proximal Xp.
Lindsay
S
S
Molecular Genetics Unit, University of Newcastle-upon-Tyne, UK.
Thiselton
D L
DL
Bateman
J B
JB
Ngo
J T
JT
Sparkes
R S
RS
Coleman
M
M
Davies
K E
KE
Bhattacharya
S S
SS
D001483:Base Sequence; D001766:Blindness / Q000235:genetics*; D002874:Chromosome Mapping; D004247:DNA / Q000235:genetics; D008040:Genetic Linkage; D006579:Heterozygote; D006801:Humans; D008969:Molecular Sequence Data; D010375:Pedigree; D014960:X Chromosome
D004247:DNA