[Effect of ethacizine on the heart conduction system and the indicators of central hemodynamics].
A trial of the antiarrhythmic drug ethacizine made in the Soviet Union which is an analogue of ethmozine was performed in 38 patients suffering from coronary heart disease. Automatism, conduction and excitation of the myocardium, hemodynamics and the antiarrhythmic effect were studied using electrophysiological methods, echo-cardiography and Holter monitoring. Ethacizine was found effective in arrhythmia. It reduces conduction in small changes of hemodynamics and myocardial contractility.
Gorshkov
V A
VA
Nesvetov
V N
VN
Kesarev
G V
GV
Sherashov
V S
VS
Mamaev
V I
VI
D000328:Adult; D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000188:drug therapy* / Q000503:physiopathology; D004562:Electrocardiography; D005260:Female; D006329:Heart Conduction System / Q000187:drug effects* / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010640:Phenothiazines / Q000627:therapeutic use*
D000889:Anti-Arrhythmia Agents; D010640:Phenothiazines; C046818:ethacizine
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