title: Acquired cystic disease of kidney associated with renal cell carcinoma in chronic dialysis patients.
abstract: We describe 2 cases of acquired cystic disease of the kidney (ACDK) associated with renal cell carcinoma in patients treated with long-term hemodialysis. Both patients have had dialysis for five and eight years, respectively. Renal cell carcinomas of these patients are small, averaging 2 cm in diameter. They are clear cell type. Atypical epithelial hyperplasia arising from cystic areas can be seen intermingling with carcinoma. This confirms that atypical epithelial hyperplasia is a precursor of renal cell carcinoma. Although the incidence of renal cell carcinoma arising in ACDK is on the rise, the issue of how to manage patients with ACDK remained unsettled and required further study.
authors.affiliation: Department of Laboratory Service, VA Medical Center, Dayton, Ohio.
authors.forename: J I
authors.initials: JI
authors.lastname: Lin
authors.forename: M
authors.initials: M
authors.lastname: Saklayen
authors.forename: M
authors.initials: M
authors.lastname: Ehrenpresis
authors.forename: N M
authors.initials: NM
authors.lastname: Hillman
mesh_terms: D000368:Aged; D002292:Carcinoma, Renal Cell / Q000150:complications / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy; D007680:Kidney Neoplasms / Q000150:complications / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D007690:Polycystic Kidney Diseases / Q000150:complications / Q000209:etiology* / Q000473:pathology; D006435:Renal Dialysis / Q000009:adverse effects*; D013997:Time Factors