[The biological effects in animals in relation to the accident at the Chernobyl Atomic Electric Power Station. 10. Cooperative immune reactions in different generations of mice].
The immune status of mice has been assessed by the whole complex of data. The permanent action of low-level radiation has been shown to suppress considerably the rate of reactions of the delayed-type hypersensitivity and "graft versus host" disease, as well as NK and specific cytolytic T-lymphocyte activity. The dynamics of accumulation and the levels of antiviral antibodies in the serum, lung and trachea extracts are virtually invariable. The resistance of experimental animals to influenza is lower than that of non-irradiated mice of the same line and age. The data obtained indicate that the immune disturbances revealed are connected not only with the alteration of lymphoid cell populations, but also with the alteration of the immune regulation mechanisms.
Savtsova
Z D
ZD
Kovbasiuk
S A
SA
Iudina
O Iu
OIu
Zaritskaia
M Iu
MIu
Voeĭkova
I M
IM
Orlovskiĭ
A A
AA
Indyk
V M
VM
Serkiz
Ia I
IaI
D000059:Accidents; D000375:Aging / Q000276:immunology / Q000528:radiation effects*; D000818:Animals; D004781:Environmental Exposure; D005260:Female; D006087:Graft vs Host Reaction / Q000276:immunology / Q000528:radiation effects; D006968:Hypersensitivity, Delayed / Q000276:immunology; D007113:Immunity, Innate / Q000276:immunology / Q000528:radiation effects; D009980:Influenza A virus; D008211:Lymphocyte Cooperation / Q000276:immunology / Q000528:radiation effects*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D009688:Nuclear Reactors; D009976:Orthomyxoviridae Infections / Q000276:immunology; D011210:Power Plants; D014455:Ukraine
Biologicheskie éffekty u zhivotnykh v sviazi s avarieĭ na Chernobyl'skoĭ AES. Soobshchenie 10. Kooperativnye immunnye reaktsii u razlichnykh pokoleniĭ mysheĭ.