Influence of nembutal on the impulse activity of cells of embryonal nervous tissue transplanted into the rat brain.
The average frequency of the impulse activity of neurons of an allograft of embryonal cortex, in the brain of adult Wistar rats, under nembutal anesthesia was four times lower than in nonanesthetized animals; at the same time the variability of the activity of the cells of the graft, with respect to the frequency and pattern of impulse activity, decreased. As compared with the unanesthetized animals, half as many cells of the graft reacted to tactile stimulation of the contralateral hind extremity; the neuronal reactions to the stimulation of somatic receptors of the ipsilateral side of the body completely disappeared.
Senatorov
V V
VV
Institute of Experimental Medicine, Academy of Medical Sciences of the USSR, Leningrad.
Obukhova
G P
GP
Silakov
V L
VL
D000758:Anesthesia; D000818:Animals; D016380:Brain Tissue Transplantation / Q000502:physiology*; D002540:Cerebral Cortex / Q000502:physiology; D004388:Dura Mater / Q000502:physiology; D004558:Electric Stimulation; D004594:Electrophysiology; D005071:Evoked Potentials / Q000187:drug effects; D005260:Female; D016332:Fetal Tissue Transplantation / Q000502:physiology*; D006614:Hindlimb / Q000502:physiology; D008839:Microelectrodes; D009431:Neural Conduction / Q000187:drug effects*; D009474:Neurons / Q000187:drug effects*; D009475:Neurons, Afferent / Q000187:drug effects / Q000502:physiology; D010424:Pentobarbital / Q000494:pharmacology*; D010812:Physical Stimulation; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D012879:Skin Physiological Phenomena
D010424:Pentobarbital