title: [Splenectomy for chronic thrombocytopenic purpura].
abstract: During the period 1985-1989, 49 patients underwent splenectomy for chronic idiopathic thrombocytopenic purpura in our department. A correct follow-up was available for 39 patients. All patients had been previously treated with corticosteroids. We evaluated the platelet count one year after the operation and the relation between this count and several preoperative and postoperative factors. We observed a favourable prognosis when the preoperative study of platelet sequestration showed splenic destruction, when the duration of symptoms was less than one year and when there was a rapid increase in the platelet count during the first week after the operation.
authors.affiliation: Service de Chirurgie Générale, Hôpital Saint-Louis, Paris.
authors.forename: M A
authors.initials: MA
authors.lastname: Cohen
authors.forename: E
authors.initials: E
authors.lastname: Bourstyn
authors.forename: M J
authors.initials: MJ
authors.lastname: Galera
authors.forename: Y
authors.initials: Y
authors.lastname: Najean
authors.forename: P
authors.initials: P
authors.lastname: Clot
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D002908:Chronic Disease; D004351:Drug Resistance; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010976:Platelet Count; D011182:Postoperative Care; D011379:Prognosis; D011696:Purpura, Thrombocytopenic / Q000097:blood / Q000188:drug therapy / Q000601:surgery*; D013156:Splenectomy / Q000379:methods*; D019966:Substance-Related Disorders
chemical_list: D000305:Adrenal Cortex Hormones
vernacular_title: Splénectomie pour purpura thrombopénique chronique.