title: Histochemical stainings, biological cultures and therapeutic responses of granulomatous lymphadenitis in Ramathibodi Hospital-prospective study of 57 cases.
abstract: The study was designed to delineate the etiology of granulomatous lymphadenitis which is one of the most common lesions encountered in our routine surgical pathology practice. Fifty-seven lymph nodes diagnosed histopathologically as granulomatous lymphadenitis were cultured and stained by special histochemical stains for tuberculosis, fungus, anaerobic and aerobic bacteria. M.tuberculosis was isolated in 60-70 per cent of lesions. The remaining 30-40 per cent of the lesions failed to demonstrate any infectious agent but most of the available follow-up cases showed satisfactory response to antituberculous drugs. Ziehl-Neelsen's stain showed very low sensitivity but excellent specificity and is still recommended for use to differentiate from other infectious agents in the areas where infectious agents are prevalent.
authors.affiliation: Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: V
authors.initials: V
authors.lastname: Sirikulchayanonta
authors.forename: R
authors.initials: R
authors.lastname: Prachaktam
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002648:Child; D003470:Culture Media / Q000592:standards; D006099:Granuloma / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology; D006651:Histocytochemistry / Q000592:standards; D006785:Hospitals, University; D006801:Humans; D008199:Lymphadenitis / Q000453:epidemiology / Q000382:microbiology* / Q000473:pathology; D008875:Middle Aged; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D013785:Thailand / Q000453:epidemiology
chemical_list: D003470:Culture Media