A physical model for the titanium-tissue interface.
X-ray photoelectron spectroscopy (XPS) was used to determine changes in titanium oxide composition, oxide stoichiometry, and adsorbed surface species as a function of exposure to model physiologic environments. The oxide on titanium became heterogeneous and polarized as a function of exposure. Changes included an increase in surface hydroxyl groups, and adsorption of H2PO4- and HPO4(2-). The heterogeneous nature of the surface led to preferential adsorption of lipoproteins, glycolipids, or both from serum.
Healy
K E
KE
Division of Biological Materials, Northwestern University, Chicago, Illinois.
Ducheyne
P
P
D001672:Biocompatible Materials; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006801:Humans; D013057:Spectrum Analysis; D014025:Titanium / Q000493:pharmacokinetics*
D001672:Biocompatible Materials; C009495:titanium dioxide; D014025:Titanium