title: Interferon-related leukoencephalopathy in a patient with renal cell carcinoma.
abstract: A 75-year-old patient with metastatic renal cell carcinoma was treated with recombinant interferon alpha-C and thereafter developed a neurologic syndrome of dementia, ataxia, confusional state, loss of concentration ability and cortical blindness. CT scan findings were compatible with leukoencephalopathy, which is reported as being a toxic effect of interferon.
authors.affiliation: Department of Oncology, Tel-Aviv Sourasky Medical Center, Tel-Aviv University, Israel.
authors.forename: O
authors.initials: O
authors.lastname: Merimsky
authors.forename: I
authors.initials: I
authors.lastname: Reider
authors.forename: E
authors.initials: E
authors.lastname: Merimsky
authors.forename: S
authors.initials: S
authors.lastname: Chaitchik
mesh_terms: D000368:Aged; D001927:Brain Diseases / Q000209:etiology*; D002292:Carcinoma, Renal Cell / Q000628:therapy*; D003711:Demyelinating Diseases / Q000209:etiology*; D006801:Humans; D007370:Interferon Type I / Q000009:adverse effects*; D007680:Kidney Neoplasms / Q000628:therapy*; D008297:Male; D011994:Recombinant Proteins
chemical_list: D007370:Interferon Type I; D011994:Recombinant Proteins