title: Extending the Pallister-Hall syndrome to include other central nervous system malformations.
abstract: Hall-Pallister syndrome is defined by specific facial anomalies, post axial polydactyly, imperforate anus, and brain anomalies including a rare diencephalic mass, hypothalamic hamartoblastoma. In this article, two patients are described with the usual features of Hall-Pallister syndrome, including diencephalic anomalies, but without hamartoblastomas. These patients may suggest an appropriate extension of the definition of the Hall-Pallister syndrome.
authors.affiliation: Division of Embryology, Teratology, and Congenital Defects, University of Washington School of Medicine, Seattle 98195.
authors.forename: D P
authors.initials: DP
authors.lastname: Finnigan
authors.forename: S K
authors.initials: SK
authors.lastname: Clarren
authors.forename: J E
authors.initials: JE
authors.lastname: Haas
mesh_terms: D000015:Abnormalities, Multiple; D001921:Brain / Q000002:abnormalities*; D005145:Face / Q000002:abnormalities*; D005260:Female; D005385:Fingers / Q000002:abnormalities*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010641:Phenotype; D013577:Syndrome; D014034:Toes / Q000002:abnormalities*