title: Familial hypomelanosis of Ito.
abstract: Two siblings presented the typical skin changes of hypomelanosis of Ito (HI) associated with mental and cerebellar signs. Their mother showed only the skin changes of HI but no neurological disturbances. HI is a hereditary disorder, in which familiarity may go unnoticed because of the different expressions of neural and cutaneous features.
authors.affiliation: Institute of Neurology, University of Bologna, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Montagna
authors.forename: G
authors.initials: G
authors.lastname: Procaccianti
authors.forename: G
authors.initials: G
authors.lastname: Galli
authors.forename: L
authors.initials: L
authors.lastname: Ripamonti
authors.forename: A
authors.initials: A
authors.lastname: Patrizi
authors.forename: A
authors.initials: A
authors.lastname: Baruzzi
mesh_terms: D000328:Adult; D001284:Atrophy; D001706:Biopsy; D002524:Cerebellar Ataxia / Q000175:diagnosis / Q000235:genetics / Q000473:pathology; D002531:Cerebellum / Q000473:pathology; D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D005799:Genes, Dominant / Q000235:genetics; D006801:Humans; D008297:Male; D008543:Melanins / Q000378:metabolism; D008544:Melanocytes / Q000473:pathology; D009422:Nervous System Diseases / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D019965:Neurocognitive Disorders / Q000175:diagnosis / Q000235:genetics / Q000473:pathology; D009460:Neurologic Examination; D010859:Pigmentation Disorders / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D012867:Skin / Q000473:pathology
chemical_list: D008543:Melanins