title: Laser-assisted angioplasty for arterial occlusion of the lower limb: initial results and follow-up.
abstract: A flashlamp-pumped pulsed dye laser operating at either 480 or 504 nm, coupled to an integral ball-tipped optical fibre, was used to recanalize occluded lower limb arteries. All channels created by the laser were augmented with balloon dilatation. We have treated 78 limbs in 71 patients; 46 limbs (59 per cent) had rest pain and 22 (48 per cent) of these had tissue loss. The median occlusion length was 18 (range 0.5-58) cm. Technical success was achieved in 58 limbs (74 per cent) with clinical success in 46 (59 per cent). Success rates fell with increasing length of occlusion. Two patients died in the perioperative period. A subgroup of 22 patients with marked discrete arterial calcification had a lower technical success rate than the subgroup without calcification (50 per cent versus 84 per cent, P less than 0.01). Both subgroups displayed a similar pattern of reclosure during follow-up. The cumulative patency rate after technical success was 67 per cent at 6 months and 45 per cent at 12 months. Forty-six (59 per cent) limbs avoided bypass surgery or amputation. Laser-assisted angioplasty may offer an alternative to femoropopliteal bypass, although the former procedure is not as durable.
authors.affiliation: Professorial Surgery Unit, St. Bartholomew's Hospital, London, UK.
authors.forename: D C
authors.initials: DC
authors.lastname: Mitchell
authors.forename: A
authors.initials: A
authors.lastname: Murray
authors.forename: R F
authors.initials: RF
authors.lastname: Wood
authors.forename: M
authors.initials: M
authors.lastname: Grasty
authors.forename: R E
authors.initials: RE
authors.lastname: Smith
authors.forename: J E
authors.initials: JE
authors.lastname: Dacie
authors.forename: T K
authors.initials: TK
authors.lastname: Walters
authors.forename: G
authors.initials: G
authors.lastname: Cotton
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary; D001157:Arterial Occlusive Diseases / Q000150:complications / Q000473:pathology / Q000601:surgery*; D002114:Calcinosis / Q000150:complications; D005260:Female; D005263:Femoral Artery / Q000473:pathology / Q000601:surgery; D006801:Humans; D007431:Intraoperative Complications; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged