title: Surgery for effort thrombosis of the subclavian vein.
abstract: Between February 1988 and March 1991, 28 patients with effort thrombosis of the subclavian vein were treated with a combined approach of thrombolytic therapy followed by surgical therapy. Three categories were seen: group I (six patients), acute stage (less than 5 days); group II (seven patients), subacute stage (6 days to 2 weeks); and group III (15 patients), chronic stage (more than 2 weeks). Group III was divided into two subgroups: subgroup A, seven patients with a short-obstructed segment (less than 1/2 inch), and subgroup B, eight patients with a long-obstructed segment (1 to 6 inches). During venography a catheter is placed within the thrombus for continuous infusion of urokinase (3000 U/kg/hr) for 12 to 24 hours. After complete clot lysis, resection of the first rib via a subclavicular approach is undertaken. Vein patch angioplasty was required in two patients in group I, six in group II, and seven in group III, subgroup A. Bypass of long-obstructed vein segments was attempted in only four (group III, subgroup B). Decompression and reestablishment of normal vein caliber was achieved in 100% of groups I and II and in 86% of group III, A. In only one patient of group III, B, a saphenous vein bypass remained open (25%). Operative technique is described.
authors.affiliation: Department of Surgery, University of Minnesota Hospital and Clinic, Minneapolis.
authors.forename: J E
authors.initials: JE
authors.lastname: Molina
mesh_terms: D015444:Exercise; D006801:Humans; D008722:Methods; D011183:Postoperative Complications; D013350:Subclavian Vein / Q000601:surgery; D013927:Thrombosis / Q000209:etiology / Q000601:surgery*