title: Lymphosarcoma with urinary bladder infiltration in a horse.
abstract: A 9-year-old Thoroughbred mare was examined because of pollakiuria, hematuria, and weight loss of 3 weeks' duration. Physical examination revealed a regular cardiac rhythm with occasional premature contractions, and a soft tissue mass in the pelvic canal palpable per rectum. Microscopic examination of urine sediment revealed numerous RBC and a large population of lymphocytes and lymphoblasts with characteristics of neoplasia. Similar cells were found in peritoneal fluid obtained by abdominocentesis. The horse was euthanatized without treatment. Necropsy revealed a soft tissue mass infiltrating the bladder, vagina, and uterus. Additional masses were found in the sublumbar muscles and myocardium. The histologic diagnosis was lymphosarcoma.
authors.affiliation: Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, New Bolton Center, Kennett Square 19348.
authors.forename: R W
authors.initials: RW
authors.lastname: Sweeney
authors.forename: A N
authors.initials: AN
authors.lastname: Hamir
authors.forename: R R
authors.initials: RR
authors.lastname: Fisher
mesh_terms: D000818:Animals; D005260:Female; D006338:Heart Neoplasms / Q000473:pathology / Q000662:veterinary; D006734:Horse Diseases / Q000473:pathology*; D006736:Horses; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology / Q000662:veterinary*; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000662:veterinary*; D014594:Uterine Neoplasms / Q000473:pathology / Q000662:veterinary; D014625:Vaginal Neoplasms / Q000473:pathology / Q000662:veterinary