[The biological effects in animals in relation to the accident at the Chernobyl Atomic Electric Power Station. 8. The status of cellular immunity in different generations of rats].
In studying immunity in laboratory rats of different generations (P, F1 and F2) brought up in Chernobyl in 1989-1990 the authors have revealed the development of leuko- and lymphopenia; decrease in the absolute content of immunocompetent cells bearing Fc receptors to IgG; stable and long-lasting suppression of blood NK cell activity; reduction of antibody-dependent cytotoxicity; and changed ability of blood lymphocytes to interact contactly with allogenic mast cells. The most considerable disorders have been found in 6- and 9-month-old F1 rats and in 3- and 6-month-old F2 rats.
Mel'nikov
O F
OF
Sambur
M B
MB
Indyk
V M
VM
Diugovskaia
L A
LA
Zaiats
T A
TA
Serkiz
Ia I
IaI
Timchenko
S V
SV
D000059:Accidents; D000375:Aging / Q000276:immunology / Q000528:radiation effects*; D000818:Animals; D000920:Antibody-Dependent Cell Cytotoxicity / Q000276:immunology / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D004781:Environmental Exposure; D007111:Immunity, Cellular / Q000276:immunology / Q000528:radiation effects*; D007694:Killer Cells, Natural / Q000276:immunology / Q000528:radiation effects; D008297:Male; D009688:Nuclear Reactors; D011210:Power Plants; D051381:Rats; D011961:Receptors, Fc / Q000276:immunology / Q000528:radiation effects; D012397:Rosette Formation; D014455:Ukraine
D011961:Receptors, Fc
Biologicheskie éffekty u zhivotnykh v sviazi s avarieĭ na Chernobyl'skoĭ AES. Soobshchenie 8. Sostoianie keltochnogo immuniteta u raznykh pokoleniĭ krys.