title: Correlation of serum ibuprofen concentration with clinical signs of toxicity in three canine exposures.
abstract: The clinical signs and serum concentrations of ibuprofen are reported for 3 canine exposures. No adverse clinical signs or abnormal laboratory parameters were observed when serum ibuprofen concentrations were less than 31 micrograms/mL. Melena and 38 mg blood urea nitrogen/dL (normal 7-26 mg/dL) were present in an animal with a serum ibuprofen of 138 micrograms/mL.
authors.affiliation: Hennepin Regional Poison Center, Minneapolis, MN 55415.
authors.forename: T W
authors.initials: TW
authors.lastname: Jackson
authors.forename: C
authors.initials: C
authors.lastname: Costin
authors.forename: K
authors.initials: K
authors.lastname: Link
authors.forename: M
authors.initials: M
authors.lastname: Heule
authors.forename: M J
authors.initials: MJ
authors.lastname: Murphy
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000139:chemically induced*; D004285:Dogs; D007052:Ibuprofen / Q000097:blood / Q000633:toxicity*; D008297:Male
chemical_list: D007052:Ibuprofen