title: [Change of T lymphocyte subsets in peripherial blood of children with malnutrition and zinc deficiency].
abstract: Sixty children with malnutrition were investigated in this study. The results showed a reduction of serum zinc in moderate and severe cases compared with the mild and normal groups. OKT3+, OKT4+ and OKT8+ cells in peripheral blood of mild malnutrition were significantly decreased in contrast to normal control. The reductive degree of OKT8+ and OKT4+ cells correlated with the severity of malnutrition. OKT8+, OKT4+ and OKT4+/OKT8+ ratio of moderate and severe malnutrition with infection were much lower than those without infection. Our findings suggested that main effective and regulative cells of cell-mediated immunity were impaired. OKT3+ and OKT4+ cells might be used as a sensitive index for early assessment of the immune function in malnutrition children.
authors.forename: B
authors.initials: B
authors.lastname: Zeng
authors.forename: Y
authors.initials: Y
authors.lastname: Qian
authors.forename: D
authors.initials: D
authors.lastname: Zheng
authors.forename: K
authors.initials: K
authors.lastname: Wu
authors.forename: M
authors.initials: M
authors.lastname: Zhou
authors.forename: Q
authors.initials: Q
authors.lastname: Gong
mesh_terms: D016516:CD4-CD8 Ratio; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009748:Nutrition Disorders / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D015032:Zinc / Q000172:deficiency*
chemical_list: D015032:Zinc