Long-term stability of diazepam injections.
Diazepam and its main degradation product 2-methyl-amino-5-chlorobenzophenon (MACB) were quantitatively determined by HPLC and spectrophotometry in one- to ten-years-old diazepam injections. The content of diazepam was within the specifications in all the samples. Not more than 1.5% degradation of diazepam was found after ten years.
Fyllingen
G
G
Military Pharmaceutical Laboratory Joint Medical Service, Oslo, Norway.
Kristiansen
F
F
Roksvaag
P O
PO
D003975:Diazepam / Q000032:analysis* / Q000737:chemistry; D004355:Drug Stability; D007267:Injections
D003975:Diazepam