Geographic distribution of xanthine oxidase, free radical scavengers, creatine kinase, and lactate dehydrogenase enzyme systems in rat heart and skeletal muscle.
The geographic distribution of the following enzyme systems is described in the rat heart (left and right ventricles) and in different skeletal muscles (soleus, plantaris, and red and white gastrocnemius): xanthine oxidase and dehydrogenase, creatine kinase isoenzymes, lactate dehydrogenase isoenzymes, and the free radical scavenger enzymes superoxide dismutase, glutathione reductase, and glutathione peroxidase. No substantial difference in enzyme activities was observed between the left and right ventricles. Skeletal muscles showed a clear distinction between enzyme activities depending on their composition of oxidative fibers and glycolytic fibers.
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Hennepin County Medical Center, Department of Laboratory Medicine and Pathology, University of Minnesota School of Medicine, Minneapolis, Minnesota 55415.
Hyde
J E
JE
Ingersoll-Stroubos
A M
AM
Theologides
A
A
D000818:Animals; D016166:Free Radical Scavengers; D006352:Heart Ventricles / Q000201:enzymology*; D007770:L-Lactate Dehydrogenase / Q000032:analysis*; D008297:Male; D009132:Muscles / Q000201:enzymology*; D010725:Phosphocreatine / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains; D013482:Superoxide Dismutase / Q000032:analysis; D014969:Xanthine Oxidase / Q000032:analysis*
D016166:Free Radical Scavengers; D010725:Phosphocreatine; D007770:L-Lactate Dehydrogenase; D013482:Superoxide Dismutase; D014969:Xanthine Oxidase