[Microalbuminuria in a population of 653 patients with type 1 and 2 diabetes].
The aim of this retrospective study was to evaluate the prevalence of microalbuminuria in type 1 and 2 diabetic patients with or without high blood pressure levels. 653 patients were involved in the study [type 1: n = 413 (normotensive: n = 298; hypertensive: n = 115); type 2: n = 240 (normotensive: n = 93; hypertensive: n = 147)]. In type 1 diabetic patients, the prevalence of microalbuminuria was of 21 per cent. Microalbuminuria was also found in 28 per cent of type 2 diabetic subjects (p less than 0.10 vs type 1). The prevalence of microalbuminuria was significantly higher in hypertensive than in normotensive diabetic subjects (28 vs 20 per cent; p less than 0.05). Blood pressure in type 1 and 2 normotensive patients was significantly higher in subjects with than without microalbuminuria. We also observed higher HbA1 levels in microalbuminuric type 1 diabetic patients. Finally, we also assessed that the prevalence of diabetic chronic complications was higher in type 1 patients with than without microalbuminuria (p less than 0.05). This relationship was not evidenced in type 2 diabetic patients. In conclusion, the prevalence of microalbuminuria in a population of type 1 and 2 diabetic patients is high. We confirm in this study the relationship between microalbuminuria, blood pressure, and HbA1.
Descamps
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Département de Médecine interne, Cliniques Universitaires UCL St-Luc, Bruxelles, Belgique.
Buysschaert
M
M
Ketelslegers
J M
JM
Hermans
M
M
Lambert
A E
AE
D000328:Adult; D000419:Albuminuria; D001794:Blood Pressure; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000503:physiopathology / Q000652:urine*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000503:physiopathology / Q000652:urine*; D003925:Diabetic Angiopathies / Q000652:urine; D003929:Diabetic Neuropathies / Q000652:urine; D003930:Diabetic Retinopathy / Q000652:urine; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000652:urine; D008297:Male; D008875:Middle Aged; D015995:Prevalence
D006442:Glycated Hemoglobin
Etude de la microalbuminurie dans une population de 653 patients diabétiques de type 1 et 2.