Diagnosis of pancreatic cancer. Serological markers.
Many serological markers that are widely used for delecting pancreatic cancer are discussed. Some are good indicators, but others are not. Among them, CA19-9 and SPan-1 radioimmunoassays have a higher sensitivity and specificity. However, these markers are neither tumor-specific nor pancreatic cancer-specific. Accurate understanding of their measurement made it possible to diagnose pancreatic cancer, even when the cancer was small, and to monitor the patients after treatment.
Satake
K
K
First Department of Surgery, Osaka City University, Medical School, Japan.
D014408:Biomarkers, Tumor / Q000097:blood; D005069:Evaluation Studies as Topic; D006801:Humans; D010190:Pancreatic Neoplasms / Q000097:blood / Q000175:diagnosis*; D011863:Radioimmunoassay / Q000592:standards; D012680:Sensitivity and Specificity; D012698:Serologic Tests
D014408:Biomarkers, Tumor