Acquired factor VIII inhibitor in a patient with adenocarcinoma of the colon-rectum.
The presence of a circulating inhibitor of factor VIII was observed and described in several pathological conditions. In the present study we describe the case of a patient with a severe haemorrhagic syndrome caused by the presence of a circulating inhibitor of factor VIII discovered following abdominal surgery for an adenocarcinoma of the colon rectum. The haemorrhagic syndrome evolved independently from the course of the neoplastic disease.
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I Cattedra di Patologia Speciale Medica, Università di Roma, La Sapienza, Italy.
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D000230:Adenocarcinoma / Q000097:blood*; D001778:Blood Coagulation Disorders / Q000097:blood; D003110:Colonic Neoplasms / Q000097:blood*; D005169:Factor VIII / Q000032:analysis / Q000037:antagonists & inhibitors*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000097:blood*
D005169:Factor VIII