title: Intestinal absorption of calcium from yogurt in lactase-deficient subjects.
abstract: Fractional intestinal absorption of calcium (FACa) was measured using radioactive calcium and 200 mg of calcium carrier provided either by yogurt or by CaCl2 in 7 lactase-deficient (L(-] and 7 normal (L(+] subjects. During the control period prior to yogurt consumption, mean calcium intake was 819 mg per day in L(-) and 931 mg per day in L(+) subjects (NS). In both groups of subjects yogurt increased FACa from 20.8 +/- 3.9% to 26.9 +/- 7.2% (P = 0.065) in L(+) subjects and from 20.2 +/- 5.6% to 23.5 +/- 6.4% (P = 0.050) in L(-) subjects. The significant increase in FACa observed in L(-) subjects indicates that yogurt, which is an autodigesting source of lactose, does not impair calcium absorption. FACa increase could reflect the lower dietary calcium intake in L(-) subjects when compared with L(+) subjects, due to avoidance of milk and non-fermented dairy products which could cause intestinal discomfort. It is concluded that yogurt is a well-tolerated and efficient source of calcium in subjects with lactase deficiency.
authors.affiliation: Service de Néphrologie, Centre Hospitalier et Universitaire, France.
authors.forename: A
authors.initials: A
authors.lastname: Wynckel
authors.forename: F
authors.initials: F
authors.lastname: Jaisser
authors.forename: T
authors.initials: T
authors.lastname: Wong
authors.forename: T
authors.initials: T
authors.lastname: Drüeke
authors.forename: J
authors.initials: J
authors.lastname: Chanard
mesh_terms: D000328:Adult; D000368:Aged; D002136:Calcium, Dietary / Q000008:administration & dosage / Q000493:pharmacokinetics*; D002149:Energy Intake; D005260:Female; D006801:Humans; D007408:Intestinal Absorption; D007787:Lactose Intolerance / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D016226:Phosphorus, Dietary / Q000008:administration & dosage; D015014:Yogurt; D001616:beta-Galactosidase / Q000172:deficiency*
chemical_list: D002136:Calcium, Dietary; D016226:Phosphorus, Dietary; D001616:beta-Galactosidase