Diclofenac-induced thrombocytopenic purpura with renal and hepatic involvement.
A case of diclofenac-induced thrombocytopenic purpura in a 59-year-old woman is described. Unlike the majority of earlier cases, ours was associated with renal insufficiency and jaundice. Despite the dramatic clinical picture, with severe thrombocytopenia and marked renal insufficiency, the prognosis appears to be excellent, as is shown in our case and in similar ones reported in the literature. A high dose of steroids is the treatment of choice.
Bondeson
J
J
Department of Medicine, Malmö General Hospital, University of Lund, Sweden.
Berglund
S
S
D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000150:complications; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D004008:Diclofenac / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007565:Jaundice / Q000139:chemically induced* / Q000150:complications; D008875:Middle Aged; D011696:Purpura, Thrombocytopenic / Q000139:chemically induced* / Q000150:complications
D004008:Diclofenac