title: Maternal temperature regulation during extradural analgesia for labour.
abstract: We have studied the effect of analgesia on maternal temperature (oral and tympanic membrane) progression in 53 women during normal spontaneous labour. Three groups were studied: two received extradural analgesia with a continuous infusion of 0.25% bupivacaine with or without the addition of fentanyl; the third group received only parenteral opioid analgesia. All patients were afebrile and without clinical evidence of infection at the beginning of the study. Both groups of patients receiving extradural analgesia had a consistent and significant increase in temperature after approximately 5 h of analgesia; no such trend was observed in the parenteral opioid group. Alterations in mechanisms of heat dissipation may explain these findings.
authors.affiliation: Department of Anaesthesia, Brigham and Women's Hospital, Boston, Massachusetts 02115.
authors.forename: W R
authors.initials: WR
authors.lastname: Camann
authors.forename: L A
authors.initials: LA
authors.lastname: Hortvet
authors.forename: N
authors.initials: N
authors.lastname: Hughes
authors.forename: A M
authors.initials: AM
authors.lastname: Bader
authors.forename: S
authors.initials: S
authors.lastname: Datta
mesh_terms: D000293:Adolescent; D000328:Adult; D015360:Analgesia, Epidural; D016362:Analgesia, Obstetrical; D001833:Body Temperature Regulation / Q000187:drug effects*; D002045:Bupivacaine; D005260:Female; D005283:Fentanyl; D006801:Humans; D007743:Labor, Obstetric / Q000502:physiology*; D009266:Nalbuphine; D011247:Pregnancy; D011446:Prospective Studies; D014432:Tympanic Membrane / Q000502:physiology
chemical_list: D009266:Nalbuphine; D005283:Fentanyl; D002045:Bupivacaine