Aggressive therapy of acute MI in the elderly.
In elderly patients with myocardial infarction, clinicians face a management catch-22: Mortality is increased in the absence of therapy, which is often withheld because elderly patients may succumb to its complications. What to do? Evidence from recent studies suggests that the benefits of aggressive therapy with early thrombolysis may outweigh the risks.
O'Connor
C M
CM
Duke University, Durham.
Califf
R M
RM
D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary; D002561:Cerebrovascular Disorders / Q000150:complications; D002986:Clinical Trials as Topic; D003327:Coronary Disease / Q000628:therapy; D006801:Humans; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy* / Q000401:mortality / Q000628:therapy; D009204:Myocardial Revascularization; D011379:Prognosis; D012306:Risk; D015912:Thrombolytic Therapy / Q000009:adverse effects