title: Neurochemical mechanisms of chronic antisocial behavior (psychopathy). A literature review.
abstract: This article reviews the important emotional correlates of chronic antisocial behavior from the standpoint of primary and secondary psychopathy. Primary psychopaths exhibit a conspicuous lack of empathetic emotions and secondary psychopaths exhibit a conspicuous excess of inappropriate emotions. The article points out the relationship between passive-avoidance learning deficits and primary psychopathy and between central nervous system serotonergic dysfunction and primary and secondary psychopathy.
authors.affiliation: Department of Psychiatry, Washington University School of Medicine, Jewish Hospital, St. Louis, Missouri 63110.
authors.forename: C E
authors.initials: CE
authors.lastname: Lewis
mesh_terms: D000328:Adult; D000374:Aggression / Q000523:psychology; D000987:Antisocial Personality Disorder / Q000209:etiology / Q000503:physiopathology* / Q000523:psychology; D001362:Avoidance Learning / Q000502:physiology; D001921:Brain / Q000378:metabolism / Q000503:physiopathology; D002648:Child; D002908:Chronic Disease; D004644:Emotions / Q000502:physiology; D006801:Humans; D008959:Models, Neurological; D012701:Serotonin / Q000378:metabolism / Q000502:physiology*
chemical_list: D012701:Serotonin