title: [Pulsed secretion of gonadotropins in polycystic ovary syndrome].
abstract: Pulsed secretion of gonadotropins was studied in 8 women suffering from polycystic ovarian syndrome, aged 23-28. Data on the time course of LH and FSH levels were processes by Santen and Bardin's method and by harmonic analysis. The results evidence that regular ejections of LH at a frequency higher than circahoralian rhythm (about 2 impulses per h) in such patients may be the cause of the development of the polycystic ovarian syndrome. Therapy with norcolut, carried out for 3 months, resulted in development of a trend to normalization of LH secretion, FSH secretion remaining unchanged.
authors.forename: M L
authors.initials: ML
authors.lastname: Alekseeva
authors.forename: E A
authors.initials: EA
authors.lastname: Alieva
authors.forename: S G
authors.initials: SG
authors.lastname: Korsakov
authors.forename: E A
authors.initials: EA
authors.lastname: Novikov
authors.forename: N D
authors.initials: ND
authors.lastname: Fanchenko
mesh_terms: D000328:Adult; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood / Q000378:metabolism; D006062:Gonadotropins / Q000097:blood / Q000378:metabolism*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism; D009640:Norethindrone / Q000627:therapeutic use; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000188:drug therapy / Q000503:physiopathology*; D013997:Time Factors
chemical_list: D006062:Gonadotropins; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D009640:Norethindrone
vernacular_title: Izuchenie impul'snogo kharaktera sekretsii gonadotropinov pri sindrome polikistoznykh iaichnikov.