title: Application of matched pair procedures to site-specific data in periodontal research.
abstract: Application of standard statistical procedures to site-specific data in periodontal research is invalid unless site-to-site dependencies are accounted for. In this paper, we present the adjustments required for valid application of matched pair procedures, including the paired t-test and McNemar's chi 2 test for correlated proportions. Examples are given involving data arising from: (1) the comparison of pre- and post-treatment clinical measurements; (ii) split-mouth protocols.
authors.affiliation: Department of Epidemiology and Biostatistics, University of Western Ontario, London, Canada.
authors.forename: A
authors.initials: A
authors.lastname: Donner
authors.forename: M
authors.initials: M
authors.lastname: Eliasziw
mesh_terms: D002710:Chlorhexidine / Q000627:therapeutic use; D003773:Dental Plaque / Q000453:epidemiology / Q000517:prevention & control; D003774:Dental Plaque Index; D005888:Gingival Pocket / Q000453:epidemiology / Q000517:prevention & control; D005891:Gingivitis / Q000453:epidemiology / Q000517:prevention & control; D006801:Humans; D016555:Matched-Pair Analysis; D015233:Models, Statistical; D010510:Periodontal Diseases / Q000453:epidemiology* / Q000628:therapy; D012107:Research Design
chemical_list: D002710:Chlorhexidine