Acute silicosis responding to corticosteroid therapy.
The course of acute silicosis usually is relentlessly progressive. Death results from cor pulmonale and respiratory failure, with mycobacterial infection a frequent serious complication. Attempts to treat the illness generally have been unavailing. We report an unusual case of acute silicosis in which improvement in clinical status, chest x-ray film findings and pulmonary function occurred following therapy with corticosteroids. To our knowledge, this is the first such case reported in the medical literature.
Goodman
G B
GB
Department of Medicine, West Virginia University, Morgantown.
Kaplan
P D
PD
Stachura
I
I
Castranova
V
V
Pailes
W H
WH
Lapp
N L
NL
D000208:Acute Disease; D000328:Adult; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D011241:Prednisone / Q000627:therapeutic use*; D011859:Radiography; D015656:Respiratory Mechanics; D012829:Silicosis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology
D011241:Prednisone