title: Vesicoureteral reflux in the renal transplantation candidate.
abstract: The incidence and severity of urinary tract infection episodes were evaluated in two groups of renal transplantation patients. Group 1 consisted of 11 patients transplanted following successful surgical correction of a noninfected vesicoureteral reflux in native kidneys, and group 2 of 28 patients transplanted with a noninfected vesicoureteral reflux. An increased incidence of acute urinary tract infection episodes was noted in group 2 as compared to group 1 (42.8 vs. 18%), with a mean of 2.6 +/- 1.4 episodes per patient in group 2 and 0.5 +/- 0.32 in group 1. Asymptomatic bacteriuria was not statistically different in the two groups (36.4 vs. 25%). In group 2, the incidence of urinary tract infection episodes increased in patients presenting high-grade (3 and 4) reflux in native kidneys. Despite the relatively low number of patients involved, our observations indicate that high-grade vesicoureteral reflux in native kidneys must be operated before transplantation, even when there is no history of urinary tract infections and urine cultures are sterile.
authors.affiliation: Clinique Urologique, CHU, Hôtel-Dieu, Nantes, France.
authors.forename: O
authors.initials: O
authors.lastname: Bouchot
authors.forename: B
authors.initials: B
authors.lastname: Guillonneau
authors.forename: D
authors.initials: D
authors.lastname: Cantarovich
authors.forename: M
authors.initials: M
authors.lastname: Hourmant
authors.forename: L
authors.initials: L
authors.lastname: Le Normand
authors.forename: J P
authors.initials: JP
authors.lastname: Soulillou
authors.forename: J M
authors.initials: JM
authors.lastname: Buzelin
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D014552:Urinary Tract Infections / Q000150:complications / Q000382:microbiology; D014718:Vesico-Ureteral Reflux / Q000150:complications* / Q000628:therapy