Postparturient metabolic and production responses in cows previously exposed to long-term treatment with somatotropin.
Postparturient metabolic and production responses were studied for 85 multiparous cows consisting of controls and animals that had been previously exposed to long-term treatment with bST. Older cows previously exposed to bST at high doses (51.6 mg/d) had lower milk yields than controls. However, there were no significant differences compared with controls in milk yield for lower dose (17.2 mg/d) older cows or parity 2 cow groups. The bST-treated groups had higher postpartum DMI, lower serum FFA, lower serum beta-hydroxybutyrate levels, and higher serum glucose than controls. Some bST-exposed groups had lower milk fat but higher milk protein levels. All bST-treated groups had significantly lower ratios of C18 to C4 to 10 milk fatty acids. Control cows of both parity groups were in higher body condition and weighed more than bST-treated cows prior to calving. The differences in postpartum metabolism may be attributed to differences in body composition resulting from bST treatment in the prior lactation, because use of body condition score prior to calving as a covariate did not substantially alter responses. The control cows probably had greater reserves of mobilizable lipid. These contentions are supported by changes in milk composition for bST-treated cows, which were consistent with animals of greater appetite, mobilizing less lipid. The bST-treated cows were probably more energetically efficient milk producers because they produced milk from feed rather than from mobilization of tissue stores. These data suggest that bST use in a prior lactation may have potential benefit in reducing risk of metabolic disorders associated with lipid mobilization in the postparturient period.
Lean
I J
IJ
University of California, Davis 95616.
Troutt
H F
HF
Bruss
M L
ML
Farver
T B
TB
Baldwin
R L
RL
Galland
J C
JC
Kratzer
D
D
Holmberg
C A
CA
Weaver
L D
LD
D020155:3-Hydroxybutyric Acid; D000367:Age Factors; D000821:Animal Feed; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001823:Body Composition; D001835:Body Weight; D002417:Cattle / Q000378:metabolism / Q000502:physiology*; D002784:Cholesterol / Q000097:blood; D004305:Dose-Response Relationship, Drug; D004435:Eating; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D013006:Growth Hormone / Q000008:administration & dosage / Q000494:pharmacology*; D006885:Hydroxybutyrates / Q000097:blood; D007657:Ketone Bodies / Q000652:urine; D007774:Lactation / Q000187:drug effects*; D007785:Lactose / Q000032:analysis; D008055:Lipids / Q000032:analysis; D008892:Milk / Q000032:analysis / Q000378:metabolism; D008894:Milk Proteins / Q000032:analysis; D010298:Parity; D049590:Postpartum Period / Q000187:drug effects* / Q000378:metabolism / Q000502:physiology
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D006885:Hydroxybutyrates; D007657:Ketone Bodies; D008055:Lipids; D008894:Milk Proteins; D013006:Growth Hormone; D002784:Cholesterol; D007785:Lactose; D020155:3-Hydroxybutyric Acid