title: [Chromosome analysis in spontaneous abortion using direct preparation of chorionic villi].
abstract: Two hundred cases of spontaneous abortions were studied by analysing chromosomes directly from chorionic villi. Abnormal karyotypes were found in 52% of the investigated cases. Among the chromosome abnormalities the most frequent were the trisomies (56.7%) followed by polyploidy (23.1%), monosomy X (15.4%) and structural anomalies (4.8%). The rapid and relatively simple method is suitable for studying the causes of spontaneous abortions, and these information may be helpful also for genetic counselling.
authors.affiliation: Györ-Moson-Sopron Megyei Kórház.
authors.forename: S
authors.initials: S
authors.lastname: Gardó
authors.forename: K
authors.initials: K
authors.lastname: Bajnóczky
mesh_terms: D000030:Abortion, Missed / Q000473:pathology*; D002824:Chorionic Villi / Q000473:pathology*; D015193:Chorionic Villi Sampling; D002869:Chromosome Aberrations / Q000175:diagnosis; D025063:Chromosome Disorders; D005260:Female; D006801:Humans; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D012641:Selection, Genetic
vernacular_title: Spontán abortumok kromoszóma-vizsgálata chorionbolyhokból direkt preparálás útján.