title: Protracted Lhermitte's sign following head and neck irradiation.
abstract: Lhermitte's sign is a rare complication of head and neck irradiation involving the delivery of dose to the cervical spinal cord. Although uncommon, symptoms of lightning-like electric sensations spreading into both arms, down the dorsal spine, and into both legs on neck flexion following head and neck irradiation, causes great concern in both the patient and the physician. This spontaneously reversible phenomenon is important for the otolaryngologist and radiation oncologist to recognize and discuss. A particularly severe and protracted case of Lhermitte's sign involving a patient recently completing a radical course of radiation for nasopharyngeal carcinoma is described in detail, including a review of the literature surrounding the cause and management of this condition.
authors.affiliation: Department of Radiation Oncology, University of Michigan Hospital, Ann Arbor.
authors.forename: A F
authors.initials: AF
authors.lastname: Thornton
authors.forename: S H
authors.initials: SH
authors.lastname: Zimberg
authors.forename: H S
authors.initials: HS
authors.lastname: Greenberg
authors.forename: M J
authors.initials: MJ
authors.lastname: Sullivan
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009068:Movement; D009303:Nasopharyngeal Neoplasms / Q000532:radiotherapy; D009333:Neck; D010292:Paresthesia / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects*; D013116:Spinal Cord / Q000528:radiation effects*