High-pass resolution perimetry and age-related loss of visual pathway neurons.
The normal, age-related decline of results of high-pass resolution perimetry (HRP) predicts a loss of approximately 9,000 retino-cortical neural channels per year of age, or about 1 channel each hour. Previously published counts of numbers of neurons in the optic nerve indicate a loss of approximately 5,000 neurons per year. The HRP results can be accounted for by postulating that neurons are lost at the same rate also in the geniculo-striate visual pathway.
Frisén
L
L
Department of Ophthalmology, University of Göteborg, Sweden.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D001369:Axons; D002452:Cell Count; D002648:Child; D006801:Humans; D008875:Middle Aged; D009900:Optic Nerve / Q000166:cytology; D012165:Retinal Ganglion Cells / Q000166:cytology*; D058609:Visual Field Tests; D014795:Visual Pathways