[The effect of finoptin on platelet aggregation, blood coagulability and fibrinolysis in patients with ischemic heart disease during physical exercise].
Exercise platelet aggregation, blood coagulability, and fibrinolysis were examined in patients prior myocardial infarction 2-3 months following the disease. Seventy patients of whom 35 had received placebo and 35 finoptin prior to exercise were studied. The platelet aggregation, blood coagulability, and fibrinolysis were explored before and after bicycle ergometric test. Following exercise, the patients on placebo showed higher platelet aggregation, blood coagulability and lower fibrinolysis, whereas those on finoption exhibited a lower increase in platelet aggregation and blood coagulability and activated fibrinolysis.
Kovalenko
V M
VM
Shunkova
E I
EI
Gol'dberg
G A
GA
Karagaeva
L G
LG
Shlafer
I D
ID
Epifantseva
N N
NN
D000328:Adult; D001777:Blood Coagulation / Q000187:drug effects*; D003327:Coronary Disease / Q000097:blood*; D005080:Exercise Test; D005342:Fibrinolysis / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology*; D014700:Verapamil / Q000494:pharmacology*
D010975:Platelet Aggregation Inhibitors; D014700:Verapamil
Vliianie finoptina na agregatsiiu trombotsitov, svertyvaemoct' krovi i fibrinoliz u bol'nykh ishimicheskoĭ bolezn'iu serdtsa pri fizicheskoĭ nagruzke.