title: Granulomatous amebic encephalitis in an AIDS patient.
abstract: A 39-year-old man with AIDS died after developing a variety of neurologic symptoms and signs. CT showed multiple enhancing lesions in the cerebral hemispheres and cerebellum. Postmortem examination revealed parenchymal hemorrhagic and necrotizing lesions with a thrombo-occlusive vasculitis due to Acanthamoeba, which was typed as Acanthamoeba group 2, probably A rhysodes, by immunofluorescence.
authors.affiliation: Department of Pathology, Beth Israel Hospital, Boston, MA 02215.
authors.forename: H A
authors.initials: HA
authors.lastname: Gardner
authors.forename: A J
authors.initials: AJ
authors.lastname: Martinez
authors.forename: G S
authors.initials: GS
authors.lastname: Visvesvara
authors.forename: A
authors.initials: A
authors.lastname: Sotrel
mesh_terms: D000048:Acanthamoeba / Q000302:isolation & purification*; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000469:parasitology; D000328:Adult; D000562:Amebiasis / Q000150:complications* / Q000469:parasitology; D000818:Animals; D001921:Brain / Q000473:pathology; D004660:Encephalitis / Q000000981:diagnostic imaging / Q000469:parasitology* / Q000473:pathology; D006099:Granuloma / Q000000981:diagnostic imaging / Q000469:parasitology* / Q000473:pathology; D006801:Humans; D008297:Male; D014057:Tomography, X-Ray Computed