Ketamine for caudal analgesia in children: comparison with caudal bupivacaine.
Fifty children undergoing inguinal herniotomy were allocated randomly to three groups to receive a caudal injection of either 0.25% bupivacaine 1 ml kg-1 with or without ketamine 0.5 mg kg-1 or ketamine 0.5 mg kg-1 with normal saline 1 ml kg-1. There was no significant difference in quality of pain relief, postoperative behaviour or analgesic requirements between the ketamine group and the two other groups. The bupivacaine-ketamine mixture provided better analgesia than the bupivacaine solution alone. Side effects such as motor weakness or urinary retention were not observed in the ketamine group.
Naguib
M
M
Department of Critical Care Medicine, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al Ain.
Sharif
A M
AM
Seraj
M
M
el Gammal
M
M
Dawlatly
A A
AA
D015360:Analgesia, Epidural; D002045:Bupivacaine; D002420:Cauda Equina; D002648:Child; D002652:Child Behavior / Q000187:drug effects; D002675:Child, Preschool; D004311:Double-Blind Method; D006552:Hernia, Inguinal / Q000601:surgery; D006801:Humans; D007223:Infant; D007649:Ketamine; D008297:Male; D010149:Postoperative Pain / Q000188:drug therapy*; D013997:Time Factors
D007649:Ketamine; D002045:Bupivacaine