Catheter infections in insulin-dependent diabetics on continuous ambulatory peritoneal dialysis.
We compared a group of 60 insulin-dependent diabetics maintained on CAPD with 60 nondiabetic matched controls to determine if the diabetic patients were at increased risk for catheter-related infections. Although catheter infection rates were 17% higher in the diabetics (1.4/year versus 1.2/year in nondiabetics), time to first catheter infection was not different between the groups (p = 0.6). Rates of peritonitis, peritonitis associated with catheter infection, multiple catheter infection, and catheter removal were also similar among the diabetics and controls. S. aureus caused 52% (42/81) of the catheter infections in the diabetics and 60% (35/58) in the controls. More catheter infections in the nondiabetics versus the diabetics lacked drainage or resulted in sterile cultures (17/75 versus 7/88 respectively, p less than or equal to 0.01), but the significance of this finding is uncertain. In conclusion, we did not find insulin-dependent diabetes mellitus to be a statistically significant risk factor for catheter-related infections.
Holley
J
J
Renal Electrolyte Division, University of Pittsburgh, Pennsylvania 15213.
Bernardini
J
J
Piraino
B
B
D001424:Bacterial Infections / Q000209:etiology* / Q000382:microbiology; D002404:Catheterization / Q000009:adverse effects*; D003922:Diabetes Mellitus, Type 1 / Q000382:microbiology; D003928:Diabetic Nephropathies / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009666:Nose / Q000382:microbiology; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*; D010538:Peritonitis / Q000209:etiology; D012189:Retrospective Studies; D012307:Risk Factors; D013211:Staphylococcus aureus / Q000302:isolation & purification