title: [Physiopathological aspects of secondary hyperuricemia].
abstract: Secondary hyperuricaemia expresses a heterogeneous group of clinical conditions generally classified according to the pathogenetic criteria. Hyperuricaemia can depend on an increased production, reduced renal excretion or on the combination of both. Myelo and lymphoproliferative diseases are clinically prevalent among the conditions accompanying this overproduction. The most frequent causes of reduced uric acid excretion are chronic renal failure and diuretic treatment. In recent years, several conditions of hyperuricaemia with mixed pathogenesis have revealed a common mechanism connected to the ATP cellular depletion.
authors.affiliation: Istituto di Clinica medica e Malattie cardiovascolari, Università, Palermo.
authors.forename: G
authors.initials: G
authors.lastname: Caimi
authors.forename: R
authors.initials: R
authors.lastname: Lo Presti
mesh_terms: D000208:Acute Disease; D003327:Coronary Disease / Q000652:urine; D064420:Drug-Related Side Effects and Adverse Reactions; D005632:Fructose; D005953:Glycogen Storage Disease Type I / Q000652:urine; D006801:Humans; D006961:Hyperparathyroidism / Q000652:urine; D006973:Hypertension / Q000652:urine; D007674:Kidney Diseases / Q000139:chemically induced / Q000652:urine; D007676:Kidney Failure, Chronic / Q000652:urine; D007855:Lead Poisoning / Q000652:urine; D009135:Muscular Diseases / Q000652:urine; D012131:Respiratory Insufficiency / Q000652:urine; D014527:Uric Acid / Q000378:metabolism / Q000652:urine*
chemical_list: D014527:Uric Acid; D005632:Fructose
vernacular_title: Aspetti fisiopathologici delle iperuricemie secondarie.