Translocation (4;14) and concomitant inv(14) in a basal cell carcinoma.
Chromosome analysis of short-term cultures from a basal cell carcinoma was performed. The analyzed karyotypes showed a pseudodiploid clone characterized by a der(4)t(4;14) (p14;p11) and a concomitant inversion of the same chromosome 4 involved in the t(4;14) with the breakpoints at p14 and q25.
Kawasaki
R S
RS
Departamento de Biologia, Instituto de Biociências, Letras e Ciências Exatas de São José do Rio Preto, UNESP, Brazil.
Caldeira
L F
LF
André
F S
FS
Gasques
J A
JA
Castilho
W H
WH
Bozola
A R
AR
Thomé
J A
JA
Tajara
E H
EH
D002280:Basal Cell Carcinoma / Q000235:genetics*; D002869:Chromosome Aberrations; D007446:Chromosome Inversion; D002883:Chromosomes, Human, Pair 14; D002894:Chromosomes, Human, Pair 4; D005260:Female; D006801:Humans; D007621:Karyotyping; D008875:Middle Aged; D009669:Nose Neoplasms / Q000235:genetics*; D014178:Translocation, Genetic; D014407:Tumor Cells, Cultured