title: Leiomyoma of the suprarenal gland in a child with ataxia-telangiectasia.
abstract: We report the occurrence of a leiomyoma of the suprarenal gland in a 10-year-old girl with ataxia-telangiectasia (A-T). Muscle cell tumors are very uncommon in this gland as they are in A-T. Possible reasons for developing nonhematologic tumors in this syndrome are reviewed. A defect in DNA repair mechanisms probably favors, in young children, the expression of tumors normally expected in the aged.
authors.affiliation: Department of Paediatric Haematology and Oncology, Cliniques Universitaires St Luc, Brussels, Belgium.
authors.forename: F
authors.initials: F
authors.lastname: Mouchet
authors.forename: J
authors.initials: J
authors.lastname: Ninane
authors.forename: S
authors.initials: S
authors.lastname: Gosseye
authors.forename: C
authors.initials: C
authors.lastname: Verellen
authors.forename: C
authors.initials: C
authors.lastname: Bonnier
authors.forename: P
authors.initials: P
authors.lastname: Evrard
authors.forename: C
authors.initials: C
authors.lastname: Vermylen
authors.forename: J M
authors.initials: JM
authors.lastname: Scheiff
authors.forename: G
authors.initials: G
authors.lastname: Cornu
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000209:etiology / Q000235:genetics / Q000473:pathology*; D001260:Ataxia Telangiectasia / Q000150:complications* / Q000235:genetics; D002648:Child; D007446:Chromosome Inversion; D005260:Female; D006403:Hematologic Tests; D006801:Humans; D007889:Leiomyoma / Q000209:etiology / Q000235:genetics / Q000473:pathology*; D009367:Neoplasm Staging; D014178:Translocation, Genetic