Pharmacologic treatment of priapism in two horses.
Benztropine mesylate was used successfully to treat priapism that developed during anesthesia in 2 horses. After IV injection, there was a rapid resolution of signs in both horses, and no side effects were observed. The choice of an effective method to treat priapism is challenging because precise causes in most patients have not been well-defined. Benztropine mesylate is a synthetic compound resulting from the combination of the active portions of atropine and diphenhydramine, and is believed effective because of its central acetyl-choline-antagonizing properties.
Wilson
D V
DV
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing 48824.
Nickels
F A
FA
Williams
M A
MA
D000768:Anesthesia, General / Q000009:adverse effects / Q000662:veterinary*; D000818:Animals; D001182:Arthroscopy / Q000662:veterinary; D001590:Benztropine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006734:Horse Diseases / Q000188:drug therapy* / Q000209:etiology; D006736:Horses; D008297:Male; D010276:Parasympatholytics / Q000627:therapeutic use*; D011317:Priapism / Q000188:drug therapy / Q000209:etiology / Q000662:veterinary*; D001744:Urinary Bladder Calculi / Q000601:surgery / Q000662:veterinary; D014546:Urinary Catheterization / Q000662:veterinary
D010276:Parasympatholytics; D001590:Benztropine