title: [Regulation of diabetes and late complications in the ambulatory treatment of patients with Type II diabetes mellitus].
abstract: In order to obtain more information on the quality of metabolic control and presence of secondary complications in type 2 diabetic patients treated in a hospital outpatient-clinic, we studied 124 of our diabetic patients (56 males, 68 females, age 65 (SD 11) years, duration of diabetes 9, range 1-32 years). HbA1c levels were 7.9% in patients on oral hypoglycaemic agents (n = 56), and 8.2% in insulin-treated patients (n = 59). Cholesterol and triglyceride levels tended to be lower in the insulin-treated patients. The prevalence of vascular abnormalities was high: in comparison with a population of general practice patients more patients had hypertension (56% vs 38%), coronary artery disease (48% vs 40%), and cerebrovascular disease (15% vs 6%). In addition, 35% of our diabetics had signs of peripheral artery disease. Retinopathy was present in 35 patients, microalbuminuria was found in 31 patients, proteinuria in 18 patients. The presence of microalbuminuria and proteinuria was a strong indicator for cardiovascular disease, polyneuropathy and retinopathy. The use of cardiovascular medication was high: 57 patients used antihypertensive therapy, 37 used diuretics, and 26 long-acting nitrates. Only 25 patients took no medication apart from to their diabetes therapy.
authors.affiliation: Academisch Ziekenhuis, afd. Inwendige Geneeskunde, Maastricht.
authors.forename: B H
authors.initials: BH
authors.lastname: Wolffenbuttel
authors.forename: J P
authors.initials: JP
authors.lastname: Sels
authors.forename: S
authors.initials: S
authors.lastname: Verhoeven
authors.forename: A C
authors.initials: AC
authors.lastname: Nieuwenhuijzen Kruseman
mesh_terms: D000368:Aged; D000553:Ambulatory Care; D000959:Antihypertensive Agents / Q000627:therapeutic use; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications / Q000628:therapy*; D004232:Diuretics / Q000627:therapeutic use; D005194:Family Practice; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010044:Outpatient Clinics, Hospital
chemical_list: D000959:Antihypertensive Agents; D004232:Diuretics; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents
vernacular_title: Diabetesregulatie en late complicaties bij poliklinisch behandelde patiënten met diabetes mellitus type II.