Poliomyelitis with special reference to immunization status.
One hundred ninety one children below 5 years of age suffering from poliomyelitis were analyzed to find out the immunization status and its correlation with the incidence of poliomyelitis. Effects of age, sex, immunization status and seasonal variation on the morbidity and mortality status were studied. The maximum number of cases were admitted during the months of July (23.6%) and August (23.1%). Of 191 cases, 143 (74.9%) had no immunization and 48 (25.1%) were partially immunized. A total of 155 (81.2%) cases had spinal polio, 23 (12.01%) bulbo-spinal polio, and 13 had (6.8%) bulbar polio. Serious illness (bulbospinal and bulbar type) was more in partially immunized children (25%) as compared to unimmunized children (16.8%). The mortality rate was more than two times higher in the partially immunized (29.6%) as compared to unimmunized children (11.2%). The possible explanation for high mortality in partially immunized children could be due to the adverse effect of OPV which has not been studied so far.
Mathur
G P
GP
Department of Pediatrics, G.S.V.M. Medical College, Kanpur.
Mathur
S
S
Gupta
V
V
Bhalla
M
M
Bhalla
J N
JN
Tripathi
V N
VN
Kini
S M
SM
Singh
S
S
D000367:Age Factors; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007114:Immunization; D015994:Incidence; D007194:India / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011051:Poliomyelitis / Q000276:immunology* / Q000401:mortality / Q000503:physiopathology; D011055:Poliovirus Vaccine, Oral / Q000009:adverse effects; D012189:Retrospective Studies; D012621:Seasons; D012737:Sex Factors
D011055:Poliovirus Vaccine, Oral