Papular acrodermatitis of childhood (Gianotti-Crosti disease).
An 11-year-old boy had lentil-sized lichenoid papules, localized to the limbs and trunk, together with acute, nonicteric, hepatitis B surface antigen-positive hepatitis. The clinical picture and course were typical of Gianotti-Crosti disease. Monoclonal antibodies were used to study the lymphocyte subpopulations and surface antigens in the inflammatory infiltrate in frozen sections of a skin biopsy specimen. The results provide data on the pathogenic mechanism of the papular exanthem.
Magyarlaki
M
M
Department of Dermatology, University Medical School of Pécs, Hungary.
Drobnitsch
I
I
Schneider
I
I
D000169:Acrodermatitis / Q000150:complications / Q000175:diagnosis; D002081:Buttocks; D002648:Child; D006509:Hepatitis B / Q000150:complications / Q000175:diagnosis; D006801:Humans; D008297:Male