title: Incompatibility of water-soluble contrast media and intravascular pharmacologic agents. An in vitro study.
abstract: In vitro incompatibilities between nine water-soluble contrast media and 21 intravascular pharmacologic agents were investigated using naked-eye observation and a centrifuge. Most of the previously reported incompatibilities were verified, and a few new incompatibilities were discovered: phentolamine mesylate with diatrizoate sodium, diatrizoate meglumine, ioxaglate, and iothalamate; diatrizoate meglumine with diazepam and meperidine hydrochloride; and diatrizoate sodium with meperidine hydrochloride. There were no incompatibilities when the pharmacologic agents investigated were mixed with ioxithalamate, iopromide, iopamidol, and iohexol.
authors.affiliation: Department of Diagnostic Radiology, Seoul National University College of Medicine, Republic of Korea.
authors.forename: S H
authors.initials: SH
authors.lastname: Kim
authors.forename: H K
authors.initials: HK
authors.lastname: Lee
authors.forename: M C
authors.initials: MC
authors.lastname: Han
mesh_terms: D001808:Blood Vessels; D003287:Contrast Media; D004347:Drug Interactions; D066298:In Vitro Techniques; D004364:Pharmaceutical Preparations / Q000008:administration & dosage
chemical_list: D003287:Contrast Media; D004364:Pharmaceutical Preparations