Organic dissociative syndrome associated with antimigraine pharmacotherapy.
This report describes an acute organic brain syndrome with a fugue-like state in association with antimigraine pharmacotherapy. The differential diagnosis of: 1. possible psychotoxic effects of the combination of propranolol, imipramine, and butalbital; 2. confusional migraine with amnesia; and 3. psychogenic dissociation is considered. Although organically induced dissociative states are of clinical, neuropsychological and medico-legal significance, the DSM-III and DSM-III-R have specific categories only for dissociative conditions that are strictly psychogenic in origin.
Good
M I
MI
Massachusetts Mental Health Center, Boston.
D000293:Adolescent; D000700:Analgesics / Q000008:administration & dosage / Q000009:adverse effects*; D001241:Aspirin / Q000008:administration & dosage / Q000009:adverse effects*; D001463:Barbiturates / Q000008:administration & dosage / Q000009:adverse effects*; D002110:Caffeine; D004213:Dissociative Disorders / Q000139:chemically induced* / Q000523:psychology; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007099:Imipramine / Q000008:administration & dosage / Q000009:adverse effects; D008881:Migraine Disorders / Q000188:drug therapy* / Q000523:psychology; D010615:Phenacetin / Q000008:administration & dosage / Q000009:adverse effects*; D019966:Substance-Related Disorders / Q000175:diagnosis / Q000523:psychology*
D000700:Analgesics; D001463:Barbiturates; D004338:Drug Combinations; D002110:Caffeine; C001220:aspirin, butalbital and caffeine drug combination; D010615:Phenacetin; D007099:Imipramine; D001241:Aspirin