title: Solid phase extraction method for rapid isolation and clean-up of some synthetic pyrethroid insecticides from human urine and plasma.
abstract: A simple and rapid method for the isolation of seven synthetic pyrethroid insecticides (methothrin, fenpropathrin, cyhalothrin, permethrin, cypermethrin, fenvalerate, deltamethrin) with a solid phase extraction (SPE), utilizing Sep-Pak C18 cartridges, from human urine and plasma is presented. The detection of the insecticides was performed using a wide bore capillary gas chromatograph (GC) with flame ionization detection (FID). The insecticide-containing samples mixed with 70% methanol were directly applied to the cartridges and eluted with 2 ml chloroform. The recoveries using the cartridges were between 90-102% for urine and 81-93% for plasma. Mixing samples with 70% methanol prior to extraction, seems very useful for the screening of synthetic pyrethroid insecticides.
authors.affiliation: Department of Forensic Chemistry, Faculty of Forensic Medicine, China Medical University, Shenyang.
authors.forename: L
authors.initials: L
authors.lastname: Junting
authors.forename: F
authors.initials: F
authors.lastname: Chuichang
mesh_terms: D002849:Chromatography, Gas; D005410:Flame Ionization; D006801:Humans; D007306:Insecticides / Q000097:blood / Q000652:urine*; D011237:Predictive Value of Tests; D011722:Pyrethrins / Q000097:blood / Q000652:urine*
chemical_list: D007306:Insecticides; D011722:Pyrethrins