title: Upper gastrointestinal mucosal lesions in chronic renal failure.
abstract: The upper gastrointestinal mucosa was studied endoscopically in 182 patients (140 males, 42 females) with chronic renal failure prior to hemodialysis. Endoscopy revealed normal mucosa in 77 patients (42.3%), inflammatory mucosal lesions in 88 (48.4%), peptic ulcer in 16 (8.8%; duodenal 15, gastric 1) and Barrett's ulcer in one patient. Upper gastrointestinal bleeding was noted at presentation in 16 (8.8%) cases and was associated with erosive gastritis, duodenitis and duodenal ulcer in 11, 3 and 2 patients respectively. Thus patients with chronic renal failure had a high prevalence of inflammatory mucosal changes.
authors.affiliation: Department of Nephrology, Indira Gandhi Institute of Medical Sciences, Sheikhpura, Patna, Bihar.
authors.forename: J
authors.initials: J
authors.lastname: Prakash
authors.forename: B K
authors.initials: BK
authors.lastname: Agrawal
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D004386:Duodenum / Q000473:pathology; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology*; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology*; D007676:Kidney Failure, Chronic / Q000473:pathology*; D008297:Male; D008875:Middle Aged