[Clinical aspects and allergy-immunologic parameters in 40 children 0-7 years of age with atopic dermatitis].
Forty children with atopic dermatitis were evaluated for history, clinical features and allergologic-immunologic parameters. Lichenoid skin lesions were found in 67.5%, follicular lesions in 57.5%, and eczematoid lesions in 50% in children. 25% of children suffered from associated food allergy, 15% from respiratory atopy, and 5% from contact urticaria. The diagnostic efficiency to show specific sensitization was 93% for Pediatric Phadiatop, 90% for Food-Multidisc (fx5 Pharmacia), 88% for skin tests (Prick), 73% for elevated total serum IgE, 65% for Phadiatop, and 60% for family history. The classification of atopic dermatitis into an extrinsic type with specific sensitizations to allergens and into an intrinsic type without specific sensitizations appears to be useful because specific sensitizations significantly correlate with severer skin condition and disease course.
Hochreutener
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Dermatologische Universitäts-Poliklinik Zürich, Ostschweizerisches Kinderspital St. Gallen.
D000485:Allergens / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000175:diagnosis* / Q000235:genetics / Q000276:immunology*; D005260:Female; D005512:Food Hypersensitivity / Q000175:diagnosis / Q000235:genetics / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007223:Infant; D007428:Intradermal Tests; D008297:Male; D012130:Respiratory Hypersensitivity / Q000175:diagnosis / Q000235:genetics / Q000276:immunology; D012307:Risk Factors
D000485:Allergens; D007073:Immunoglobulin E
Klinik und allergologisch-immunologische Parameter bei 40 Kindern von 0-7 Jahren mit atopischer Dermatitis.