title: Secondary syphilis presenting as cutaneous nodules in a patient previously treated for laryngeal carcinoma.
abstract: A person who had previously been treated for laryngeal carcinoma presented with the new onset of asymptomatic nodular skin lesions. The preliminary differential diagnosis included cutaneous metastasis. Examination of a biopsy specimen of the lesions and results of subsequent laboratory investigation ruled out the possibility of recurrent metastatic disease and established a diagnosis of secondary syphilis. The differential diagnosis of nodular lesions that resemble a lymphoid neoplasm or a cutaneous metastasis in a patient treated for cancer should also include secondary syphilis.
authors.affiliation: Department of Dermatology, University of Texas Medical School, Houston 77030.
authors.forename: P R
authors.initials: PR
authors.lastname: Cohen
authors.forename: S R
authors.initials: SR
authors.lastname: Hymes
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000556:secondary*; D003937:Diagnosis, Differential; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000175:diagnosis / Q000556:secondary*; D013591:Syphilis, Cutaneous / Q000175:diagnosis* / Q000473:pathology