Rate of metastasis from C3H mouse mammary tumours.
Transplants from the same C3H mouse mammary tumour have been used for radiobiological experiments with curative intent for more than 8 years. During that time, the rate of metastasis to the lungs has varied between 0 and 63% and an explanation has been sought for this change. The results of immunological assays showed no obvious pattern. An inverse relationship was found between tumour latency and metastasis.
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Richard Dimbleby Department of Cancer Research UMDS, St Thomas' Hospital, London, UK.
D000818:Animals; D005260:Female; D006979:Hyperthermia, Induced; D015994:Incidence; D008175:Lung Neoplasms / Q000453:epidemiology / Q000556:secondary*; D008297:Male; D015674:Mammary Neoplasms, Animal / Q000276:immunology / Q000473:pathology* / Q000628:therapy; D051379:Mice; D008809:Mice, Inbred C3H; D009368:Neoplasm Transplantation; D012737:Sex Factors