title: Ischemic stroke. How to keep the first one from happening.
abstract: The prevention of stroke has undenied merit. Recognition of stroke-inducing conditions (eg, cardiac diseases associated with embolism, polycythemia) provides opportunities for specific prevention strategies. For a larger number of patients, however, risk factors for degenerative vascular disease should be addressed. The evidence for efficacy is strongest for treatment of hypertension, and smoking cessation also reduces the risk of stroke. The value of treatment of hyperlipidemia in reducing the incidence of a first stroke remains to be demonstrated. Optimal management of carotid bruit and asymptomatic stenosis will be clarified by results of ongoing clinical trials. On the basis of available data, use of aspirin by healthy persons without risk factors cannot be recommended as a method for preventing a first ischemic stroke.
authors.affiliation: Department of Neurology, Hennepin County Medical Center, Minneapolis, MN 55415.
authors.forename: S R
authors.initials: SR
authors.lastname: Bundlie
mesh_terms: D001241:Aspirin / Q000627:therapeutic use; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000188:drug therapy; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications / Q000188:drug therapy; D006973:Hypertension / Q000150:complications / Q000188:drug therapy; D002546:Ischemic Attack, Transient / Q000145:classification / Q000209:etiology / Q000517:prevention & control*; D008297:Male; D012307:Risk Factors; D012737:Sex Factors; D016540:Smoking Cessation
chemical_list: D001241:Aspirin