Toxicity after self-poisoning by ingestion of potassium chloroplatinite.
A 31 year-old man ingested 10 mL of a photographic toning solution containing 600 mg of potassium chloroplatinite in a suicide attempt. Subsequent toxic effects included acute oliguric renal failure, metabolic acidosis, fever, muscle cramps, gastroenteritis and rhabdomyolysis. Laboratory abnormalities included mildly elevated liver enzymes and elevated peripheral blood neutrophil and eosinophil counts. All symptoms and signs of toxicity resolved over a six day hospital stay with supportive medical management only; thereafter he was lost to medical follow-up. A spot serum platinum concentration was 245 mcg/dL and a spot urine platinum concentration was 4200 mcg/L.
Woolf
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Division of General Pediatrics, Children's Hospital, Boston, Massachusetts.
Ebert
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D000138:Acidosis / Q000139:chemically induced*; D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000628:therapy; D000328:Adult; D056486:Chemical and Drug Induced Liver Injury; D005440:Fluid Therapy; D006801:Humans; D007202:Indicators and Reagents; D008297:Male; D010984:Platinum / Q000097:blood / Q000506:poisoning* / Q000652:urine; D017671:Platinum Compounds; D013406:Suicide, Attempted
D007202:Indicators and Reagents; D017671:Platinum Compounds; C002999:chloroplatinic acid; D010984:Platinum