[Cardiolipin antibodies in non-specific aortic arteritis].
Cardiolipin antibodies are detected in the sera from patients having a wide range of clinical manifestations, including venous and arterial thrombosis, obstetric abnormality, damaged CHS and diseased vascular wall. To clarify the clinical value of cardiolipin antibodies, 21 patients with non-specific aortic arteritis were studied. The antibodies were determined by enzyme immunoassay. Their higher levels were found in 5 (24%) patients. The patients who were positive for cardiolipin antibodies showed a significant increase in the incidence of occlusive lesions (p less than 0.001) and a moderate increase in that of valvular heart diseases. The findings suggest that cardiolipin antibodies might contribute to the pathogenesis of non-specific of aortic arteritis.
Naconov
E L
EL
Arabidze
G G
GG
Sugraliev
A B
AB
Kovalev
V N
VN
Aleksandrova
L Z
LZ
D000293:Adolescent; D000328:Adult; D001025:Aortitis / Q000276:immunology*; D001323:Autoantibodies / Q000097:blood*; D002308:Cardiolipins / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D001323:Autoantibodies; D002308:Cardiolipins
Antitela k kardiolipinu pri nespetsificheskom aortoarteriite.