Cystic endocrine tumor of the pancreas.
A large cystic tumor in the pancreatic body was found incidentally in an 85-yr-old male. A distal pancreatectomy was performed after a diagnosis of cystadenocarcinoma. Microscopic examination of the resected specimen revealed a pancreatic cystic endocrine tumor; however, this tumor produced no symptoms. Immunohistochemical studies of the tumor cells showed positivity for gastrin, neuron-specific enolase, chromogranin A, and synaptophysin, and two cell types of neurosecretory granules were recognized in electron-microscopic studies. Although endocrine tumors of the pancreas are usually solid and cystic change occurs only rarely, such tumors should be considered in the differential diagnosis of patients who have a cystic lesion in the pancreas.
Nojima
T
T
Department of Pathology, Hokkaido University School of Medicine, Sapporo, Japan.
Kojima
T
T
Kato
H
H
Inoue
K
K
Nagashima
K
K
D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D010187:Pancreatic Hormones / Q000378:metabolism; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D009384:Paraneoplastic Endocrine Syndromes / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology
D010187:Pancreatic Hormones