Cathepsin D activity of an aortic polyester double velour DALLON graft.
Cathepsin D activity, protein and acid-soluble tyrosine contents in a polyester double velour DALLON graft were evaluated in an experiment lasting one year, performed in 36 male mongrel dogs. The cathepsin D activity in the intimal, medial and adventitial layers of the graft on the 7th day of the experiment was much higher than in a normal artery and vein. In the intimal and medial layers of the graft, this activity increased in the 1st and 4th months of the experiment. In all the layers, cathepsin D activity fell to the level of the activity in normal vessels after one year of the experiment. The protein and acid-soluble tyrosine contents in all the graft layers were highest on the 7th day after which they decreased gradually.
Głowiński
S
S
Department of Vascular Surgery and Transplantology, Medical School, Białystok, Poland.
Worowski
K
K
D000818:Animals; D001012:Aorta, Abdominal / Q000201:enzymology / Q000601:surgery; D001807:Blood Vessel Prosthesis; D004285:Dogs; D006083:Graft Occlusion, Vascular / Q000175:diagnosis / Q000201:enzymology*; D008297:Male; D011091:Polyesters
D011091:Polyesters