title: Chronic actinic dermatitis: a time course study of histopathological changes.
abstract: We report herein a case of chronic actinic dermatitis in which histopathological changes were observed on several occasions during the course of 2 years. The findings were quite different among stages of the eruption. At a half year after the appearance of the lesion, histological findings revealed eczematous changes. However, gradually a granulomatous change appeared with histiocytes and giant cells. Although the mechanism of histogenesis is not clear, the appearance of histiocytic giant cells seems to be unusual in chronic actinic dermatitis.
authors.affiliation: Department of Dermatology, Kansai Medical University, Moriguchi, Osaka, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Miyauchi
authors.forename: T
authors.initials: T
authors.lastname: Horio
authors.forename: Y
authors.initials: Y
authors.lastname: Asada
authors.forename: M
authors.initials: M
authors.lastname: Hayami
mesh_terms: D000368:Aged; D001706:Biopsy; D002908:Chronic Disease; D006801:Humans; D008297:Male; D010328:Patch Tests; D010787:Photosensitivity Disorders / Q000209:etiology / Q000473:pathology*; D013997:Time Factors; D014466:Ultraviolet Rays / Q000009:adverse effects