title: A computer simulation model for cost-effectiveness analysis of cardiovascular disease prevention.
abstract: In this paper a computer simulation model for cost-effectiveness analysis of cardiovascular disease prevention is presented. Cost-effectiveness analysis makes it possible to compare the cost-effectiveness of different interventions in order to maximize the health effects for a given amount of resources. The computer simulation model was written in Turbo-Pascal to be used on an IBM-PC-compatible. The model was based on the 8-year logistic multivariate risk equations for CHD and stroke from the Framingham Heart Study, but the regression coefficients can easily be changed if local data exist. The main advantages with the model are that it is easy to use, transparent, and flexible. The model was mainly developed for scientific purposes, but should be useful also for educational purposes and clinical decision analysis. The modelling approach used should also be useful in many other medical areas.
authors.affiliation: Department of Health and Society, Linköping University, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: Johannesson
authors.forename: J
authors.initials: J
authors.lastname: Hedbrant
authors.forename: B
authors.initials: B
authors.lastname: Jönsson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000191:economics* / Q000209:etiology / Q000517:prevention & control*; D003198:Computer Simulation; D003362:Cost-Benefit Analysis / Q000379:methods*; D006801:Humans; D008017:Life Expectancy; D016015:Logistic Models; D008875:Middle Aged; D015999:Multivariate Analysis; D011788:Quality of Life; D012307:Risk Factors; D014481:United States; D026712:Value of Life