Exacerbation of fibrous dysplasia associated with an adolescent pregnancy.
Fibrous dysplasia is a metabolic skeletal disorder in which the medullary spaces of affected bones are replaced by fibro-osseous tissue. Patients with fibrous dysplasia usually become symptomatic during childhood; the adolescent patient we describe is unusual because she was not known to suffer from fibrous dysplasia until she became pregnant and experienced a dramatic reactivation of the symptoms. The therapeutic implication of this case and reproductive counselling for young women with fibrous dysplasia are discussed.
Stevens-Simon
C
C
Department of Pediatrics, University of Colorado Health Science Center, Denver, Colorado.
Stewart
J
J
Nakashima
I I
II
White
M
M
D000293:Adolescent; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis