Histological evolution of peripheral T-cell lymphomas. Study of six cases.
The authors report 6 cases of histological transformation in peripheral T-cell lymphomas of low grade of malignancy. The transformation occurs in 75% of the cases, in extra-nodal sites and corresponds to a monomorphic of pleiomorphic large cell type. There is no discordance in the immunologic results between the two phases. The transformation seems to occur earlier than in B lymphomas, with a relative frequency of hematological manifestations and no therapeutic response.
Horschowski
N
N
Institut Paoli-Calmettes, Marseille, France.
Sainty
D
D
Sebahoun
G
G
George
F
F
Bouabdallah
R
R
Stoppa
A M
AM
Maraninchi
D
D
Blaise
D
D
Carcassonne
Y
Y
D000368:Aged; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D005260:Female; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology / Q000503:physiopathology; D016411:Lymphoma, T-Cell, Peripheral / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged