title: Cytogenetic study of a papillary thyroid carcinoma with a rearranged chromosome 10.
abstract: Cytogenetic findings of a multifocal papillary thyroid cancer and a metastatic lymph node from a 29-year-old white female patient are reported. Two clonal aberrations were observed: a trisomy 7 in one nodule, and a rearranged chromosome 10 in a separate nodule and in a lymph node. The rearrangement of 10q described here is similar to other published cases and is relevant for interpreting the molecular findings associated with thyroid cancer.
authors.affiliation: Michigan Cancer Foundation, Detroit.
authors.forename: M E
authors.initials: ME
authors.lastname: Herrmann
authors.forename: A
authors.initials: A
authors.lastname: Mohamed
authors.forename: G
authors.initials: G
authors.lastname: Talpos
authors.forename: S R
authors.initials: SR
authors.lastname: Wolman
mesh_terms: D000328:Adult; D002291:Carcinoma, Papillary / Q000473:pathology*; D002879:Chromosomes, Human, Pair 10; D002897:Chromosomes, Human, Pair 7; D002999:Clone Cells; D005260:Female; D006801:Humans; D007621:Karyotyping; D008207:Lymphatic Metastasis; D013964:Thyroid Neoplasms / Q000473:pathology*; D014314:Trisomy