title: [Rheumatoid arthritis and multiple neoplasms].
abstract: In patients with rheumatoid arthritis the appearance of neoplastic disease has been fundamentally described of lymphoproliferative origin. The case of a 59 year old woman with rheumatoid arthritis of a 4 year evolution is reported. The patient was treated with gold salts and methotrexate and presented successively a bronchogenic carcinoma and a non-Hodgkin lymphoma. The epidemiologic studies in the relation of rheumatoid arthritis-neoplasia are discussed and the pathogenic hypotheses to the immune alterations as well as the treatments employed are described.
authors.affiliation: Seccione de Reumatología, Hospital d'Alacant, Servei Valencià de Salut.
authors.forename: J
authors.initials: J
authors.lastname: Ivorra
authors.forename: B
authors.initials: B
authors.lastname: Massutí
authors.forename: J
authors.initials: J
authors.lastname: Román
authors.forename: C
authors.initials: C
authors.lastname: Balañá
authors.forename: J
authors.initials: J
authors.lastname: Portilla
authors.forename: E
authors.initials: E
authors.lastname: Pascual
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D001172:Arthritis, Rheumatoid / Q000150:complications*; D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D008228:Lymphoma, Non-Hodgkin / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000150:complications*; D014057:Tomography, X-Ray Computed
vernacular_title: Artritis reumatoide y neoplasia múltiple.