[Micronucleus formation in the bone marrow cells of chronically irradiated mice with subsequent acute gamma irradiation].
With the use of the micronuclear test method it has been shown that mice preirradiated with gamma rays at a low dose rate exhibit a decreased frequency of chromosome aberrations induced in bone marrow cells by subsequent acute exposure to gamma radiation as compared to mice not subjected to preliminary irradiation. Such animals have a higher radioresistance with respect to the survival rate. The results obtained suggest the possibility of induction by ionizing radiation, at a low dose rate, of adaptive repair response at the organism level.
Fomenko
L A
LA
Kozhanovskaia
Ia K
IaK
Gaziev
A I
AI
D000222:Adaptation, Physiological / Q000528:radiation effects; D000818:Animals; D001853:Bone Marrow / Q000528:radiation effects* / Q000648:ultrastructure; D002869:Chromosome Aberrations; D004307:Dose-Response Relationship, Radiation; D004912:Erythrocytes / Q000528:radiation effects / Q000648:ultrastructure; D005720:Gamma Rays; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D048629:Micronuclei, Chromosome-Defective / Q000528:radiation effects* / Q000648:ultrastructure; D015162:Micronucleus Tests; D011833:Radiation Injuries, Experimental / Q000401:mortality / Q000473:pathology; D014916:Whole-Body Irradiation
Issledovanie obrazovaniia mikroiader v kletkakh kostnogo mozga khronicheski obluchennykh mysheĭ pri ikh posleduiushchem ostrom gamma-obluchenii.