title: Analysis of the activation of poly(ADP-ribose) polymerase by various types of DNA.
abstract: In this work, we examined the activation of poly(ADP-ribose) polymerase by various types of DNA. We have found that the best activator for poly(ADP-ribose) polymerase is an octanucleotide. However, the use of a defined activated DNA is also suitable.
authors.affiliation: Poly (ADP-ribose) Metabolism Group, CHUL Research Center and Laval University, Ste-Foy, Que., Canada.
authors.forename: C
authors.initials: C
authors.lastname: Hengartner
authors.forename: J
authors.initials: J
authors.lastname: Lagueux
authors.forename: G G
authors.initials: GG
authors.lastname: Poirier
mesh_terms: D000818:Animals; D002417:Cattle; D004247:DNA / Q000737:chemistry; D004789:Enzyme Activation; D007700:Kinetics; D009838:Oligodeoxyribonucleotides / Q000737:chemistry*; D011065:Poly(ADP-ribose) Polymerases / Q000737:chemistry*; D011131:Polyribonucleotides / Q000096:biosynthesis*
chemical_list: D009838:Oligodeoxyribonucleotides; D011131:Polyribonucleotides; D004247:DNA; D011065:Poly(ADP-ribose) Polymerases