title: Contractile protein alterations in heart failure.
abstract: After nearly three decades of intense investigation, the precise cellular mechanisms underlying impaired contractility in heart failure remain to be defined. Nevertheless, growing use of the tools of molecular biology promises new insights into how alterations of contractile proteins mediate the functional derangements of failure.
authors.affiliation: Division of Cardiology, University of Arkansas College of Medicine.
authors.forename: J P
authors.initials: JP
authors.lastname: Lindemann
mesh_terms: D000199:Actins / Q000737:chemistry / Q000502:physiology* / Q000648:ultrastructure; D006333:Heart Failure / Q000503:physiopathology*; D006801:Humans; D009200:Myocardial Contraction / Q000502:physiology*; D009218:Myosins / Q000737:chemistry / Q000502:physiology* / Q000648:ultrastructure; D014335:Tropomyosin / Q000737:chemistry / Q000502:physiology / Q000648:ultrastructure; D014336:Troponin / Q000737:chemistry / Q000502:physiology / Q000648:ultrastructure
chemical_list: D000199:Actins; D014335:Tropomyosin; D014336:Troponin; D009218:Myosins