Subdural fat effusion complicating parenteral nutrition.
A preterm infant fed parenterally through a central venous catheter developed a subdural effusion containing fat emulsion. Subsequent postmortem examination failed to demonstrate any vascular abnormality that might have explained this rarely reported complication. Although retrograde flow of feeding solutions into cerebral veins seems a likely explanation, the exact mechanism remains uncertain.
Rushforth
A
A
Department of Paediatrics and Child Health, University of Leeds.
Green
M A
MA
Levene
M I
MI
Puntis
J W
JW
D002405:Catheterization, Central Venous; D005217:Fat Emulsions, Intravenous / Q000032:analysis; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000209:etiology*; D010288:Parenteral Nutrition / Q000009:adverse effects*; D013353:Subdural Effusion / Q000209:etiology* / Q000378:metabolism
D005217:Fat Emulsions, Intravenous