[Biliopancreatic bypass and disorders of iron absorption].
Sideropenic anemia is a common long-term complication of surgical bilio-pancreatic bypass for morbid obesity, and is frequently resistant to oral iron therapy. To study the pathogenesis of this phenomenon we investigated 7 such patients clinically and biologically, with special emphasis on iron absorption. Our results show that sideropenia, consistently present and frequently complicated by anemia, is due to deficient iron absorption and that this malabsorption is non-selective. Replacement therapy, when indicated, should therefore use the parenteral route.
Stucki
A
A
Département de médecine interne, Centre hospitalier universitaire vaudois, Lausanne.
Grob
J P
JP
Chapuis
G
G
Meyer
A
A
Christeler
P
P
Bachmann
F
F
D000328:Adult; D000747:Anemia, Hypochromic / Q000188:drug therapy / Q000209:etiology*; D015904:Biliopancreatic Diversion / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D007408:Intestinal Absorption; D007501:Iron / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000601:surgery*
D007501:Iron
Courts-circuits bilio-pancréatiques et troubles de l'absorption du fer.