Lysophospholipase activity of Ascaris suum-induced mouse peritoneal neutrophils and eosinophils.
Lysophospholipase activity of mouse peritoneal neutrophils and eosinophils was studied to determine if neutrophils and eosinophils have lysophospholipase activity when treated with Ascaris suum whole worm extract, if zymosan activated complement can induce increased lysophospholipase activity, or if the immune status of the host has an effect on lysophospholipase activity. Neutrophils from noninfected or infected (immunized) mice were found to have increased lysophospholipase activity when treated with A. suum whole worm extract or zymosan activated complement demonstrating neutrophils as a source of lysophospholipase activity in the presence or absence of an immune response. Eosinophils from immunized mice had increased lysophospholipase activity when treated with either A. suum whole worm extract or zymosan activated complement.
Laubach
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HE
Department of Microbiology, Southeastern University of the Health Sciences, North Miami Beach, Florida 33162.
Hall
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PA
D000818:Animals; D001200:Ascaris / Q000472:pathogenicity*; D003167:Complement Activation; D004804:Eosinophils / Q000201:enzymology*; D007274:Injections, Intraperitoneal; D007963:Leukocytes, Mononuclear / Q000201:enzymology; D008245:Lysophospholipase / Q000378:metabolism*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009504:Neutrophils / Q000201:enzymology*; D010533:Peritoneal Lavage; D014020:Tissue Extracts / Q000494:pharmacology; D015054:Zymosan / Q000494:pharmacology
D014020:Tissue Extracts; D015054:Zymosan; D008245:Lysophospholipase