title: Microbiological exploitation of cardiac glycosides and alkaloids from Garcinia kola, Borreria ocymoides, Kola nitida and Citrus aurantifolia.
abstract: The four medicinal plants, Garcinia kola (roots), Borreria ocymoides (leaves), Kola nitida (bark) and Citrus aurantifolia (roots) were screened for phytochemical components. They were found to contain tannins, phlobatannins, polyphenols, hydroxymethyl anthraquinones, glucides, saponins, alkaloids, cardiac glycosides, flavanoids and reducing compounds. The aqueous and alcoholic extracts as well as alkaloids and cardiac glycosides of the medicinal plants were tested on various pathogenic bacteria. They were found to inhibit such organisms as Staphylococcus aureus, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, beta-haemolytic streptococci, Escherichia coli and Neisseria gonorrhoeae. The usefulness of the phytochemical bases of these plants as potential sources of pharmaceutical drug preparation is discussed.
authors.affiliation: Department of Biological Sciences, University of Calabar, Cross River State, Nigeria.
authors.forename: R U
authors.initials: RU
authors.lastname: Ebana
authors.forename: B E
authors.initials: BE
authors.lastname: Madunagu
authors.forename: E D
authors.initials: ED
authors.lastname: Ekpe
authors.forename: I N
authors.initials: IN
authors.lastname: Otung
mesh_terms: D000470:Alkaloids / Q000302:isolation & purification / Q000494:pharmacology*; D002301:Cardiac Glycosides / Q000302:isolation & purification / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D002301:Cardiac Glycosides; D010936:Plant Extracts