A case of malignant hyperthermia?
An acute episode of a malignant hyperthermia-like syndrome is described which occurred after suxamethonium and isoflurane anaesthesia in a 41-year-old healthy male patient undergoing a minor elective hand operation. Dantrolene therapy rapidly reversed the life-threatening signs. Laboratory results appeared to confirm the suspicion of malignant hyperthermia. However, the in vitro contracture test, which was carried out according to the standards of the European Malignant Hyperthermia Group, was equivocal.
Broekema
A A
AA
Department of Anaesthesiology, University Hospital Groningen, The Netherlands.
Boersma
G A
GA
Hennis
P J
PJ
D000328:Adult; D003620:Dantrolene / Q000627:therapeutic use; D006801:Humans; D007530:Isoflurane; D008297:Male; D008305:Malignant Hyperthermia / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D009132:Muscles / Q000473:pathology; D009211:Myoglobin / Q000097:blood; D013390:Succinylcholine; D013997:Time Factors
D009211:Myoglobin; D007530:Isoflurane; D003620:Dantrolene; D013390:Succinylcholine