Preliminary nuclear magnetic resonance studies on human saliva.
Of gustatory-stimulated human whole, parotid, submandibular and sublingual saliva only parotid saliva, a serous rather than mucous secretion, presented a relatively well-resolved proton NMR spectrum with satisfactory signal-to-noise ratio in a short time (30 min). The proton signal intensities showed significant circadian rhythms related to the circadian rhythms of protein concentrations in saliva. Age- and sex-associated differences in spectra were not observed for healthy saliva. On the other hand, marked differences in the spectra were observed for patients with suspected sialoadenitis.
Yamada-Nosaka
A
A
Department of Oral Radiology, School of Dentistry, Tokushima University, Japan.
Fukutomi
S
S
Uemura
S
S
Hashida
T
T
Fujishita
M
M
Kobayashi
Y
Y
Kyogoku
Y
Y
D000328:Adult; D002940:Circadian Rhythm; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D012463:Saliva / Q000737:chemistry* / Q000378:metabolism; D012471:Salivary Proteins and Peptides / Q000737:chemistry; D012793:Sialadenitis / Q000175:diagnosis*
D012471:Salivary Proteins and Peptides