[Functional disorders of the central nervous system in patients with pulmonary tuberculosis].
Two groups of pulmonary tuberculosis patients were followed up to reveal the relation between the lipid peroxidation (LPO) processes and the function of the central nervous system (CNS) in pulmonary tuberculosis. Group 1 (n = 76) included subjects with normal baseline electroencephalographic findings; group 2 (n = 41) consisted of those with profound changes in the electroencephalogram. The findings of LPO processes were assessed by the blood levels of malonic dialdehyde and alpha-tocopherol. Group 2 showed a direct relationship between the progression of neurotic symptoms and the abnormal changes in the values of LPO processes. It is concluded that it is expedient to use antioxidants in the combined treatment of pulmonary tuberculosis patients to eliminate the baseline CNS changes caused by the specific process.
Chelnokova
N V
NV
Starostenko
E V
EV
Salpagarov
A M
AM
Kruglova
E G
EG
D001921:Brain / Q000378:metabolism*; D002540:Cerebral Cortex / Q000503:physiopathology*; D004569:Electroencephalography; D006801:Humans; D015227:Lipid Peroxidation / Q000502:physiology*; D008315:Malondialdehyde / Q000097:blood; D008995:Monoamine Oxidase / Q000172:deficiency; D014397:Tuberculosis, Pulmonary / Q000503:physiopathology*; D014811:Vitamin E Deficiency / Q000503:physiopathology*; D005680:gamma-Aminobutyric Acid / Q000172:deficiency
D008315:Malondialdehyde; D005680:gamma-Aminobutyric Acid; D008995:Monoamine Oxidase
Narusheniia funktsional'nogo sostoianiia tsentral'noĭ nervnoĭ sistemy u bol'nykh tuberkulezom legkikh.