title: Middle childhood onset of interictal psychosis.
abstract: The authors describe three children (mean age = 7.8 years) with complex partial epilepsy, left temporal lobe involvement, and interictal schizophrenia-like psychosis. As described in adults with complex partial epilepsy, these children met DSM-III criteria for schizophrenia, their affect was intact, and they demonstrated no negative signs of schizophrenia. Unlike adult epileptic patients, these children demonstrated psychotic symptomatology despite inadequate seizure control and after a short latency period. The possible role of early onset seizures, temporal lobe lesions, and kindling on the developing brain are discussed.
authors.affiliation: Division of Child Psychiatry, University of California, Los Angeles.
authors.forename: R
authors.initials: R
authors.lastname: Caplan
authors.forename: W D
authors.initials: WD
authors.lastname: Shields
authors.forename: L
authors.initials: L
authors.lastname: Mori
authors.forename: S
authors.initials: S
authors.lastname: Yudovin
mesh_terms: D002648:Child; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000503:physiopathology / Q000523:psychology*; D005260:Female; D006212:Hallucinations / Q000503:physiopathology / Q000523:psychology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D019965:Neurocognitive Disorders / Q000503:physiopathology / Q000523:psychology*; D011569:Psychiatric Status Rating Scales; D012561:Schizophrenia, Childhood / Q000503:physiopathology / Q000523:psychology*; D013702:Temporal Lobe / Q000503:physiopathology