[Behavior of Sa plasmid in tularemia pathogen cells].
The genome of Sa plasmid is shown to be a subject of genetical rearrangements in Francisella tularensis cells. The rearrangements either result in plasmid integration into the host cell genome or intramolecular amplification of cat-gene with the subsequent excision and recombination of the derivative plasmids. Stable inheritance of the plasmid is registered after integration while plasmid elimination occurs in case of extrachromosomal localisation.
Pomerantsev
A P
AP
Domaradskiĭ
I V
IV
Shishkova
N A
NA
Ershov
Iu V
IuV
D002876:Chromosomes, Bacterial; D004269:DNA, Bacterial / Q000235:genetics / Q000378:metabolism; D004587:Electrophoresis, Agar Gel; D004926:Escherichia coli / Q000235:genetics; D005604:Francisella tularensis / Q000235:genetics*; D005798:Genes, Bacterial; D006868:Hydrolysis; D008854:Microscopy, Electron; D009693:Nucleic Acid Hybridization; D010957:Plasmids; D011995:Recombination, Genetic; D015183:Restriction Mapping
D004269:DNA, Bacterial
Povedenie plazmidy Sa v kletkakh tuliaremiĭnogo mikroba.