title: Prolonged storage of tissues at low temperatures does not preclude their use for ultrastructural studies.
abstract: A cost-effective method for electron microscopic study of snap-frozen surgical specimens is described. The method is available to any surgical pathology laboratory equipped with a deep freezer and allows the performance of ultrastructural observations on archival material.
authors.affiliation: Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia.
authors.forename: J M
authors.initials: JM
authors.lastname: Minda
authors.forename: I A
authors.initials: IA
authors.lastname: Lubensky
authors.forename: G G
authors.initials: GG
authors.lastname: Pietra
mesh_terms: D015925:Cryopreservation; D005069:Evaluation Studies as Topic; D006801:Humans; D008854:Microscopy, Electron; D010338:Pathology, Clinical / Q000379:methods*; D012016:Reference Values; D013997:Time Factors