Liver high performance liquid chromatographic porphyrin profiles in experimental porphyria induced by peroxidizing herbicides.
The effect of peroxidizing herbicides on the liver porphyrin content of experimental animals was examined. Mice treated with the herbicide oxadiazon accumulated uroporphyrin and protoporphyrin in the liver. Formesafen-treated mice accumulated uroporphyrin and heptacarboxylic porphyrin.
Krijt
J
J
Department of Pathological Physiology, First Medical Faculty, Charles University, U Prague, Czechoslovakia.
Sanitrák
J
J
Vokurka
M
M
Janousek
V
V
D000818:Animals; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004195:Disease Models, Animal; D006540:Herbicides / Q000009:adverse effects*; D008099:Liver / Q000737:chemistry*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D011164:Porphyrias / Q000139:chemically induced* / Q000378:metabolism; D011166:Porphyrins / Q000032:analysis*
D006540:Herbicides; D011166:Porphyrins