title: [Activation of (ADP-ribose) polymerase by DNA fragmented by micrococcal nuclease and DNAase I].
abstract: Activation of (ADP-ribose) polymerase by DNA fragments obtained by digestion of calf thymus DNA with micrococcal nuclease and DNAase I was studied. It was found that activation of the enzyme is due to its interaction with the terminal parts of double-stranded DNA fragments, the level of activation being independent of the size of DNA fragments.
authors.forename: L V
authors.initials: LV
authors.lastname: Karabashian
authors.forename: A G
authors.initials: AG
authors.lastname: Mkhitarian
authors.forename: D L
authors.initials: DL
authors.lastname: Arutiunian
mesh_terms: D000818:Animals; D002417:Cattle; D004247:DNA / Q000378:metabolism*; D003850:Deoxyribonuclease I / Q000378:metabolism*; D004591:Electrophoresis, Polyacrylamide Gel; D004789:Enzyme Activation; D006868:Hydrolysis; D008836:Micrococcal Nuclease / Q000378:metabolism*; D011065:Poly(ADP-ribose) Polymerases / Q000378:metabolism*
chemical_list: D004247:DNA; D011065:Poly(ADP-ribose) Polymerases; D003850:Deoxyribonuclease I; D008836:Micrococcal Nuclease
vernacular_title: Aktivatsiia (ADP-riboza) polimerazy DNK, fragmentirovannoĭ mikrokokkovoĭ nukleazoĭ i DNKazoĭ I.