[The characteristics of Staphylococcus aureus peptidoglycan in the spectrum of the reactivity of human lymphocytes to bacterial peptidoglycans].
The sensitivity of lymphocytes of healthy persons to S. aureus peptidoglycan as compared with that to the polyclonal stimulator zymosan C3b and peptidoglycans of other bacteria (Streptococcus faecalis, Escherichia coli, Bacterium bifidum) was analyzed with a test system permitting the determination of specific reactivity to peptidoglycans. The analysis showed that at the peak of luminol-dependent chemiluminescence (25-30 minutes) individual reactivity to S. aureus peptidoglycan varied within wide limits (the coefficient of lymphocyte stimulation was 1.4-9.6, 3.5 +/- 0.6), exceeding sensitivity to other bacteria, as well as the values obtained in the negative control. The conclusion of the wide spread of sensitization to S. aureus peptidoglycan and the possibility of using this preparation for the study of cell-mediated immunity reactions was made.
Osipov
O A
OA
Sibiriakova
N I
NI
Astaf'ev
D G
DG
Rassanov
S P
SP
Maianskiĭ
A N
AN
D001644:Bifidobacterium / Q000276:immunology; D003179:Complement C3b / Q000494:pharmacology; D013293:Enterococcus faecalis / Q000276:immunology; D004926:Escherichia coli / Q000276:immunology; D006801:Humans; D008163:Luminescent Measurements; D008165:Luminol; D008213:Lymphocyte Activation / Q000187:drug effects; D008214:Lymphocytes / Q000187:drug effects* / Q000276:immunology; D010457:Peptidoglycan / Q000276:immunology*; D013211:Staphylococcus aureus / Q000276:immunology*; D015054:Zymosan / Q000494:pharmacology
D010457:Peptidoglycan; D008165:Luminol; D003179:Complement C3b; D015054:Zymosan
Kharakteristika peptidoglikana Staphylococcus aureus v spektre reaktivnosti limfotsitov cheloveka k bakterial'nym peptidoglikanam.