Sensitive and rapid reversed-phase liquid chromatography-fluorescence method for determining bisphenol A diglycidyl ether in aqueous-based food simulants.
A method has been developed for determination of bisphenol A diglycidyl ether (BADGE) in 3 aqueous-based food simulants: water, 15% (v/v) ethanol, and 3% (w/v) acetic acid. BADGE is extracted with C18 cartridges and the extract is concentrated under a stream of nitrogen. BADGE is quantitated by reversed-phase liquid chromatography with fluorescence detection. Relative precision at 200 micrograms/L was 3.4%, the detection limit of the method was 0.1 micrograms/L, and recoveries of spiking concentrations from 1 to 8 micrograms/L were nearly 100%. Relative standard deviations for the method ranged from 3.5 to 5.9%, depending on the identity of the spiked aqueous-based food simulant.
Paseiro Losada
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P
Universidad de Santiago de Compostela, Facultad de Farmacia, Departamento de Química Analítica, Nutrición y Bromatología, Spain.
López Mahía
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P
Vázquez Odériz
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L
Simal Lozano
J
J
Simal Gándara
J
J
D000085:Acetates / Q000032:analysis; D019342:Acetic Acid; D001559:Benzhydryl Compounds; D002851:Chromatography, High Pressure Liquid / Q000379:methods* / Q000706:statistics & numerical data; D004852:Epoxy Compounds / Q000032:analysis*; D000431:Ethanol / Q000032:analysis; D005504:Food Analysis / Q000379:methods*; D011786:Quality Control; D012996:Solutions; D014867:Water / Q000032:analysis; D000098826:Bisphenol A Compounds
D000085:Acetates; D019342:Acetic Acid; D001559:Benzhydryl Compounds; D004852:Epoxy Compounds; D000431:Ethanol; D012996:Solutions; D014867:Water; C019273:bisphenol A diglycidyl ether; D000098826:Bisphenol A Compounds