title: Lower extremity arterial occlusive disease.
abstract: The clinician must first understand the natural history of chronic lower extremity ischemia before making a decision regarding therapeutic options. Clearly, mild ischemia as evidenced by claudication does not place the patient at significant risk for limb loss. Initial conservative treatment emphasizing abstinence from tobacco products, control of underlying medical maladies, and an exercise program, along with patient reassurance, will adequately treat the majority of claudicators. When ischemia is present, patient education regarding foot care and avoidance of trauma are beneficial. Limb-threatening ischemia often requires revascularization. Adequate preoperative cardiologic evaluation and intraoperative monitoring have greatly reduced the morbidity and mortality of arterial reconstruction. Selection of the appropriate recipient vessel and bypass conduit enables limb salvage, whereas amputation would have been performed just a few years ago. Continued analysis of treatment outcomes will further define appropriate intervention in the future.
authors.affiliation: Division of Vascular Surgery, Mount Sinai Medical Center, Cleveland, Ohio.
authors.forename: H I
authors.initials: HI
authors.lastname: Darvin
authors.forename: T A
authors.initials: TA
authors.lastname: King
mesh_terms: D001157:Arterial Occlusive Diseases / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D001161:Arteriosclerosis / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006801:Humans; D007511:Ischemia / Q000175:diagnosis / Q000628:therapy; D007866:Leg / Q000098:blood supply*; D013923:Thromboembolism / Q000175:diagnosis / Q000209:etiology / Q000628:therapy