Leukogenic effect of complex indigo powder.
Oral administration of complex indigo powder, an anti-scrofula powder, at a daily dose of 0.5 g/kg, raised the leukocyte count in rats injured by irradiation, but prophylactic administration could not prevent the leukopenia induced by irradiation. This dosage did not affect growth in rats and oral doses up to 6 g/kg did not induce any toxic reactions in mice.
Liu
C X
CX
Tianjin Institute of Pharmaceutical Research, State Pharmaceutical Administration of China.
He
W G
WG
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000633:toxicity; D005260:Female; D006128:Growth / Q000187:drug effects / Q000528:radiation effects; D006410:Hematopoiesis / Q000187:drug effects*; D007203:Indigo Carmine; D007211:Indoles / Q000494:pharmacology / Q000633:toxicity; D007928:Lethal Dose 50; D007958:Leukocyte Count; D007962:Leukocytes / Q000187:drug effects* / Q000528:radiation effects; D007970:Leukopenia / Q000517:prevention & control; D008297:Male; D051379:Mice; D010946:Plants, Medicinal / Q000737:chemistry*; D011833:Radiation Injuries, Experimental / Q000517:prevention & control; D051381:Rats; D011919:Rats, Inbred Strains
D004365:Drugs, Chinese Herbal; D007211:Indoles; D007203:Indigo Carmine