[Effect of a carnitine analog on the level of bile lipids of the enterohepatic system in rabbits in cholelithiasis].
Lipid components were studied in enterohepatic system of rabbits with cholelithiasis after administration of plant components contained in meadow hay as well as of their mixture with a synthetic analogue of carnitine. Hypothetic mechanism of the carnitine derivative effect, contributing to elevation of phosphatidyl choline production in hepatocytes and to accumulation of the phospholipid in bile, is discussed. During the treatment course the calculous form of hepatocholecystitis was not detected in the experimental animals.
Bogdarin
Iu A
IuA
Kalvin'sh
I Ia
IIa
D000818:Animals; D001646:Bile / Q000378:metabolism*; D002331:Carnitine / Q000031:analogs & derivatives / Q000494:pharmacology*; D002769:Cholelithiasis / Q000201:enzymology*; D005260:Female; D050356:Lipid Metabolism; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D010713:Phosphatidylcholines / Q000096:biosynthesis; D011817:Rabbits
D010713:Phosphatidylcholines; D002331:Carnitine
Vliianie analoga karnitina na urovni zhelchnykh lipidov énterogepaticheskoĭ sistemy u krolikov pri kholelitiaze.