[Pulsed secretion of gonadotropins in polycystic ovary syndrome].
Pulsed secretion of gonadotropins was studied in 8 women suffering from polycystic ovarian syndrome, aged 23-28. Data on the time course of LH and FSH levels were processes by Santen and Bardin's method and by harmonic analysis. The results evidence that regular ejections of LH at a frequency higher than circahoralian rhythm (about 2 impulses per h) in such patients may be the cause of the development of the polycystic ovarian syndrome. Therapy with norcolut, carried out for 3 months, resulted in development of a trend to normalization of LH secretion, FSH secretion remaining unchanged.
Alekseeva
M L
ML
Alieva
E A
EA
Korsakov
S G
SG
Novikov
E A
EA
Fanchenko
N D
ND
D000328:Adult; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood / Q000378:metabolism; D006062:Gonadotropins / Q000097:blood / Q000378:metabolism*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood / Q000378:metabolism; D009640:Norethindrone / Q000627:therapeutic use; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000188:drug therapy / Q000503:physiopathology*; D013997:Time Factors
D006062:Gonadotropins; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D009640:Norethindrone
Izuchenie impul'snogo kharaktera sekretsii gonadotropinov pri sindrome polikistoznykh iaichnikov.