[Protein metabolism in patients with atherosclerosis using a 15(N) isotope].
Incorporation of 15N into blood plasma proteins and blood cells was studied in 11 patients with ischemic heart disease and peripheric atherosclerosis and in 7 healthy volunteers after oral administration of 15NH4Cl (95 atm%/15N) at a dose of 3 g per 70 kg of body mass. Metabolism of fibrinogen was stimulated, while incorporation of 15N into thrombocyte proteins was decreased in the patients with atherosclerosis as compared with healthy persons. Possible reasons of these alterations are discussed.
Barleben
Kh
Kh
Vagenknekht
K
K
Iung
K
K
Iunker
L
L
Khaĭne
Kh
Kh
D001161:Arteriosclerosis / Q000097:blood*; D001792:Blood Platelets / Q000378:metabolism; D001798:Blood Proteins / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009587:Nitrogen Isotopes; D012016:Reference Values
D001798:Blood Proteins; D009587:Nitrogen Isotopes
Issledovaniia obmena belkov u bol'nykh aterosklerozom s pomoshch'iu izotopa (15)N.