Dissolution of gall-stones in vitro.
An in vitro study on dissolution of 36 gall-stones obtained from 3 patients (12 stones from each patient) was carried out in heparin, bile salt and clofibrate solutions of different strengths. Heparin was found to be a poor solvent while bile salt (sodium desoxycholate) proved better and clofibrate the best solvent in various concentrations used. In addition 3 stones, one from each patient, were placed in normal saline to serve as control.
Modi
R P
RP
Department of Surgery, JLN Medical College, Ajmer.
Jain
T C
TC
Baid
J C
JC
Maheshwari
M
M
D001647:Bile Acids and Salts / Q000627:therapeutic use*; D002769:Cholelithiasis / Q000188:drug therapy* / Q000473:pathology; D002994:Clofibrate / Q000627:therapeutic use*; D006493:Heparin / Q000627:therapeutic use*; D006801:Humans; D066298:In Vitro Techniques
D001647:Bile Acids and Salts; D006493:Heparin; D002994:Clofibrate