title: Further studies on acid phosphatase in obese subjects.
abstract: Low activity genetic variants of acid phosphatase (ACP1) are positively associated with extreme body mass deviations in obese subjects. The same pattern has been found in non-diabetic children, in diabetic pregnant women, and in non-diabetic adult subjects. Low activity variants of ACP1 also show a positive association with family history of obesity, supporting the hypothesis of an enhancing action of these variants on expressivity of obesity.
authors.affiliation: Chair of Human Development, 2nd University of Rome School of Medicine, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Paggi
authors.forename: P
authors.initials: P
authors.lastname: Borgiani
authors.forename: F
authors.initials: F
authors.lastname: Gloria-Bottini
authors.forename: S
authors.initials: S
authors.lastname: Russo
authors.forename: I
authors.initials: I
authors.lastname: Saponara
authors.forename: M
authors.initials: M
authors.lastname: Banci
authors.forename: A
authors.initials: A
authors.lastname: Amante
authors.forename: N
authors.initials: N
authors.lastname: Lucarini
authors.forename: E
authors.initials: E
authors.lastname: Bottini
mesh_terms: D000135:Acid Phosphatase / Q000235:genetics*; D000328:Adult; D002648:Child; D005260:Female; D014644:Genetic Variation; D006801:Humans; D008297:Male; D009765:Obesity / Q000201:enzymology* / Q000235:genetics; D010641:Phenotype; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000201:enzymology / Q000235:genetics
chemical_list: D000135:Acid Phosphatase