title: [Use of hemoperfusion and cholinesterase in acute poisoning with organophosphate cholinesterase inhibitors--clinical analysis of 50 patients].
abstract: The authors present a retrospective analysis of 50 patients with acute intoxication with various organophosphate cholinesterase inhibitors who were treated in the course of 8 years by comprehensive conservative and extracorporeal elimination treatment. The mean age of the patients was 38 years. During therapy conservative treatment was used (gastric lavage, repeated lavage of the large intestine, forced diuresis, TMB-4 fusion through activated carbon, amberlite XAD-2 and XAD-4, haemodialysis). A total of 63 haemoperfusions and 15 simultaneous haemoperfusions with haemodialysis were performed. Treatment was successful in 92%. The results of treatment depended on early attendance of the patient in the dialyzation centre, on the onset of intense comprehensive treatment and the concurrent presence of other diseases.
authors.affiliation: IV. interná klinika, Fakultná nemocnica s poliklinikou, Kosice.
authors.forename: M
authors.initials: M
authors.lastname: Mydlík
authors.forename: P
authors.initials: P
authors.lastname: Mizla
authors.forename: J
authors.initials: J
authors.lastname: Klimcík
authors.forename: K
authors.initials: K
authors.lastname: Derzsiová
authors.forename: S
authors.initials: S
authors.lastname: Palko
mesh_terms: D000328:Adult; D002800:Cholinesterase Inhibitors / Q000506:poisoning*; D002802:Cholinesterases / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D006464:Hemoperfusion; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D008297:Male; D008875:Middle Aged; D009943:Organophosphorus Compounds; D011041:Poisoning / Q000628:therapy
chemical_list: D002800:Cholinesterase Inhibitors; D007306:Insecticides; D009943:Organophosphorus Compounds; D002802:Cholinesterases
vernacular_title: Pouzitie hemoperfúzie a cholínesterázy pri akútnej otrave orgánofosforovými inhibítormi cholínesteráz--klinický rozbor 50 chorých.