title: Alpha-interferon and oral fluorouracil in the treatment of unremovable and/or metastatic renal cancer.
abstract: We present the results obtained in a study of the pharmacological action (phase II) of alpha-interferon and oral fluorouracyl administered in our 2-year study (Feb. 1988-Feb. 1990) in 10 patients suffering from surgically unremovable or metastatic renal cancer. Our results were: 1 patient with complete regression of lung metastasis; 5 with progressive disease within 3-4 months from beginning of treatment and 2 deaths with stable disease after 4-5 months. Two patients abandoned treatment and their disease progressed within 4-5 months.
authors.affiliation: Department of Urology, Hospital Clinic, University of Barcelona, Spain.
authors.forename: J A
authors.initials: JA
authors.lastname: Romero
authors.forename: R
authors.initials: R
authors.lastname: Alvarez-Vijande
authors.forename: J M
authors.initials: JM
authors.lastname: Gil-Vernet
authors.forename: R
authors.initials: R
authors.lastname: Samsón
authors.forename: I
authors.initials: I
authors.lastname: Fernández
authors.forename: R
authors.initials: R
authors.lastname: Gutiérrez
authors.forename: P
authors.initials: P
authors.lastname: Carretero
mesh_terms: D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000556:secondary; D003131:Combined Modality Therapy; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D016898:Interferon-alpha / Q000008:administration & dosage* / Q000009:adverse effects; D007680:Kidney Neoplasms / Q000473:pathology / Q000628:therapy*; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008875:Middle Aged
chemical_list: D016898:Interferon-alpha; D005472:Fluorouracil