Serotonin and behavior: emphasis on motor control.
Electrophysiologic studies of brain serotonergic neurons in behaving animals indicate that their activity is closely related to the sleep-wake-arousal cycle and to certain specific types of repetitive motor activity. A variety of other environmental and physiologic manipulations are ineffective in altering the activity of this neurochemical system. An attempt is made to relate these results to well-known involvement of brain serotonin in human affective disorders.
Jacobs
B L
BL
Program in Neuroscience, Princeton University, N.J.
D000818:Animals; D001522:Behavior, Animal / Q000502:physiology; D001921:Brain / Q000502:physiology*; D002415:Cats; D002940:Circadian Rhythm / Q000502:physiology; D003866:Depressive Disorder / Q000503:physiopathology; D006801:Humans; D009043:Motor Activity / Q000502:physiology*; D009771:Obsessive-Compulsive Disorder / Q000503:physiopathology; D011903:Raphe Nuclei / Q000502:physiology; D051381:Rats; D011985:Receptors, Serotonin / Q000502:physiology; D012701:Serotonin / Q000502:physiology*; D012890:Sleep / Q000502:physiology; D014851:Wakefulness / Q000502:physiology
D011985:Receptors, Serotonin; D012701:Serotonin