Irradiated volume and arytenoid edema after radiotherapy for T1 glottic carcinoma.
From May 1982 through December 1986, 116 T1 glottic carcinomas were treated with radiotherapy in a prospective randomized study to determine the effect of radiation field size. Patients were treated with a total dose of 60 Gy over six weeks using 4 MV X-ray, wedge filter and shell. Local control rates treated with a field size of 5 x 5 cm2 and 6 x 6 cm2 were 93% and 95%, respectively. Persistent laryngeal edema occurred in 4% of cases treated with 5 x 5 cm2 and 21% with 6 x 6 cm2 (p less than 0.02). The rate of late laryngeal edema was dependent upon the treatment volume. A larger treatment field yielded a higher minor complication rate without improvement of local control rate.
Inoue
T
T
Department of Radiation Therapy, Center for Adult Diseases, Osaka, Japan.
Inoue
T
T
Chatani
M
M
Teshima
T
T
D001193:Arytenoid Cartilage / Q000528:radiation effects*; D002277:Carcinoma / Q000150:complications / Q000473:pathology / Q000532:radiotherapy*; D005374:Filtration / Q000295:instrumentation; D005931:Glottis; D006801:Humans; D015994:Incidence; D007819:Laryngeal Edema / Q000453:epidemiology / Q000209:etiology*; D007822:Laryngeal Neoplasms / Q000150:complications / Q000473:pathology / Q000532:radiotherapy*; D009367:Neoplasm Staging; D011446:Prospective Studies; D011878:Radiotherapy / Q000295:instrumentation; D011879:Radiotherapy Dosage