Psychometric detection of schizotypy: perceptual aberration and physical anhedonia in relatives of schizophrenics.
We administered scales of Perceptual Aberration (PERAB) and Physical Anhedonia (PHYSAN), traits that may be related to risk for schizophrenia, to 54 schizophrenics, 146 of their first-degree relatives (evaluated for schizophrenia-related disorders), and 178 normal subjects (screened for psychotic disorders in them or their relatives). For both scales, there was a significant effect of group membership. For the PERAB scale, the schizophrenics had higher scores than the normal subjects, who had higher scores than the relatives. For the PHYSAN scale, schizophrenics had higher scores than their relatives, who had higher scores than the normal subjects. Patterns of familial correlations also suggested that physical anhedonia, but not perceptual aberration, may be familial among schizophrenics and their relatives. The PHYSAN scale, but not the PERAB one, may be a useful indicator of liability for schizophrenia among the relatives of affected probands.
Clementz
B A
BA
University of Minnesota, Minneapolis 55455.
Grove
W M
WM
Katsanis
J
J
Iacono
W G
WG
D000328:Adult; D000342:Affective Symptoms / Q000175:diagnosis* / Q000235:genetics* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D010468:Perceptual Disorders / Q000175:diagnosis* / Q000235:genetics* / Q000523:psychology*; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D011594:Psychometrics; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis* / Q000235:genetics*; D012565:Schizophrenic Psychology; D012569:Schizotypal Personality Disorder / Q000175:diagnosis* / Q000235:genetics* / Q000523:psychology