title: [Croup and air pollutants: results of a two-year prospective longitudinal study].
abstract: The Reutlingen/Tübingen/Rottenburg region in Baden-Württemberg is characterized by medium and small sized towns and rural areas. In 1986/87 875 cases of croup were registered there by the treating physicians during a 24-months period. In consideration of meteorological and virological "disturbing variables" the influence of the measured air pollution by SO2, NO, NO2, CO, ozone and dust on croup frequency was computed by means of statistical regression methods. For the months September till March, the main manifestation period of croup, weak but statistically significant influences of the daily means of NO and NO2 were found, for the whole year influences of NO, NO2, and CO. During the winter months temperature correlates positively and velocity of wind negatively, both statistically with significance, to croup frequency. The essential conditions of croup are individual and familiar disposition on the one hand, virus infections on the other. Air pollution of a concentration like given in the investigated region was found to be a weak additional factor that favours the manifestation of croup.
authors.affiliation: Abt. Kinderheilkunde II, Universitäts-Kinderklinik Tübingen.
authors.forename: H
authors.initials: H
authors.lastname: Rebmann
authors.forename: R
authors.initials: R
authors.lastname: Huenges
authors.forename: H E
authors.initials: HE
authors.lastname: Wichmann
authors.forename: E M
authors.initials: EM
authors.lastname: Malin
authors.forename: H R
authors.initials: HR
authors.lastname: Hübner
authors.forename: A
authors.initials: A
authors.lastname: Röll
authors.forename: G
authors.initials: G
authors.lastname: Hörz
authors.forename: R
authors.initials: R
authors.lastname: Hub
authors.forename: C
authors.initials: C
authors.lastname: Walter
authors.forename: G
authors.initials: G
authors.lastname: Döller
mesh_terms: D000393:Air Pollutants / Q000009:adverse effects*; D002248:Carbon Monoxide / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D003440:Croup / Q000209:etiology*; D004391:Dust / Q000009:adverse effects; D005260:Female; D005858:Germany; D006801:Humans; D007223:Infant; D008137:Longitudinal Studies; D008297:Male; D009569:Nitric Oxide / Q000009:adverse effects; D009609:Nitrous Oxide / Q000009:adverse effects; D010126:Ozone / Q000009:adverse effects; D011446:Prospective Studies; D012044:Regression Analysis; D012307:Risk Factors; D012621:Seasons; D013458:Sulfur Dioxide / Q000009:adverse effects; D013696:Temperature; D014919:Wind
chemical_list: D000393:Air Pollutants; D004391:Dust; D013458:Sulfur Dioxide; D009569:Nitric Oxide; D010126:Ozone; D002248:Carbon Monoxide; D009609:Nitrous Oxide
vernacular_title: Krupp und Luftschadstoffe: Ergebnisse einer Zweijährigen prospektiven Längsschnittstudie.