[Spontaneous cleft palate in CF#1/Ohu mice].
We found a spontaneous cleft palate in a mouse of CF#1/Ohu (Ohu University, Japan). Further, the frequency of the spontaneous cleft palate in strains of CF#1/Jms (Institute of Medical Science, University of Tokyo, Japan) and CF#1/Jah (National Institute of Animal Health, Japan) were about 3%, respectively. The frequency and the types of spontaneous cleft palate in CF#1 were clearly different from those in A/J and CL/Fr strains which were used as model animals of lip and cleft palate. We think that CF#1 is the new animal models to analyze a cleft palate genetically and biochemically.
Matsushima
Y
Y
Department of Laboratory Animal Science, Ohu University, School of Dentistry, Fukushima, Japan.
Ohne
M
M
Irino
T
T
Maki
M
M
D000818:Animals; D002972:Cleft Palate / Q000473:pathology*; D004195:Disease Models, Animal; D005260:Female; D051379:Mice; D008815:Mice, Inbred Strains