Failure to demonstrate natriuretic activity in the posterior pituitary after immunoneutralization of the vasopressin content.
The attempt to demonstrate the presence of a natriuretic substance in the posterior pituitary after immunoneutralization of the AVP content failed. Rats infused i.v. AVP-immunoneutralized posterior pituitary extract did not respond by natriuresis to a saline infusion, in contrast to those infused untreated posterior pituitary extract. Thus, vasopressin seems to be the natriuretic substance in the posterior pituitary extract.
Ponec
J
J
Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Czechoslovakia.
Földes
O
O
Lichardus
B
B
D000818:Animals; D000906:Antibodies; D001127:Arginine Vasopressin / Q000276:immunology / Q000502:physiology*; D007163:Immunosorbent Techniques; D008297:Male; D009318:Natriuresis / Q000502:physiology*; D010904:Pituitary Gland, Posterior / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D014020:Tissue Extracts / Q000494:pharmacology
D000906:Antibodies; D014020:Tissue Extracts; D001127:Arginine Vasopressin