title: The organization and expression of the human L7a ribosomal protein gene.
abstract: The genomic structure and sequence of the human ribosomal protein L7a (rpL7a) and its transcriptional start sites have been determined. The gene contains eight exons and seven introns spread over 3179 bp. The human rpL7a gene is similar to other mammalian ribosomal protein genes in containing a short first exon, a short 5' untranslated leader and its transcriptional start sites at C residues embedded in a polypyrimidine tract. The 25 bp polypyrimidine tract containing the two human rpL7a start sites is the longest polypyrimide tract so far observed for a mammalian ribosomal protein gene.
authors.affiliation: Department of Eukaryotic Gene Organization and Expression, Imperial Cancer Research Fund, London, U.K.
authors.forename: P
authors.initials: P
authors.lastname: Colombo
authors.forename: J
authors.initials: J
authors.lastname: Yon
authors.forename: M
authors.initials: M
authors.lastname: Fried
mesh_terms: D001483:Base Sequence; D002899:Chromosomes, Human, Pair 9; D005091:Exons / Q000235:genetics; D015870:Gene Expression; D016678:Genome; D006801:Humans; D007438:Introns / Q000235:genetics; D008969:Molecular Sequence Data; D005810:Multigene Family / Q000235:genetics*; D012269:Ribosomal Proteins / Q000235:genetics*; D014158:Transcription, Genetic / Q000235:genetics
chemical_list: C057838:RPL7A protein, human; D012269:Ribosomal Proteins