Diabetes insipidus 9 years after cessation of therapy for acute lymphoblastic leukemia.
A case of a 16-year-old who developed diabetes insipidus (DI) 9 years after cessation of therapy for ALL is reported. Because hereditary and traumatic factors are excluded as a cause of DI in this patient, possible explanations may be leukemic CNS relapse, secondary brain tumor, primitive idiopathic DI, and late sequelae of CNS radiochemotherapy.
Dibenedetto
S P
SP
Department of Hematology and Pediatrics, University Hospital, Catania, Italy.
Mancuso
G R
GR
Samperi
P
P
Di Cataldo
A
A
Ragusa
R
R
Caruso-Nicoletti
M
M
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects; D002648:Child; D016371:Cranial Irradiation / Q000009:adverse effects; D003919:Diabetes Insipidus / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000628:therapy*; D013997:Time Factors