title: Food intake after hatching inhibits the growth hormone induced stimulation of the thyroxine to triiodothyronine conversion in the chicken.
abstract: The effect of a single injection of 10 micrograms chicken GH on circulating thyroid hormones as well as in vitro liver 5'-monodeiodination (5'-D) activity was studied in posthatch chicks submitted to different feeding conditions. One group was normally fed after hatching, a second group was only fed after three days and a third group was food deprived after 2 days of feeding. Combination of all results indicates that the start of food intake abolishes the stimulatory effect of a GH injection on circulating T3 and liver 5'-D activity. Food deprivation after a period of food intake restores the GH effect on plasma T3 but not on liver 5'-D.
authors.affiliation: Laboratory of Comparative Endocrinology, K. U. Leuven, Belgium.
authors.forename: V M
authors.initials: VM
authors.lastname: Darras
authors.forename: A
authors.initials: A
authors.lastname: Vanderpooten
authors.forename: L M
authors.initials: LM
authors.lastname: Huybrechts
authors.forename: L R
authors.initials: LR
authors.lastname: Berghman
authors.forename: E
authors.initials: E
authors.lastname: Dewil
authors.forename: E
authors.initials: E
authors.lastname: Decuypere
authors.forename: E R
authors.initials: ER
authors.lastname: Kühn
mesh_terms: D000818:Animals; D002645:Chickens / Q000378:metabolism*; D004435:Eating; D005502:Food; D005508:Food Deprivation; D013006:Growth Hormone / Q000494:pharmacology*; D007453:Iodide Peroxidase / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D013974:Thyroxine / Q000097:blood*; D014284:Triiodothyronine / Q000097:blood*
chemical_list: D014284:Triiodothyronine; D013006:Growth Hormone; D007453:Iodide Peroxidase; D013974:Thyroxine