title: Effect of repeated immobilization stress on the uptake of exogenous [3H]dopamine in adrenal chromaffin cells of mice.
abstract: Uptake of [3H]dopamine in adrenal chromaffin cells of the mouse during repeated immobilization was examined by autoradiography. Repeated daily immobilization of mice resulted in an increased uptake of [3H]dopamine to the level of denervated chromaffin cells. The increase was observed only in adrenaline-storing (A) cells, not in noradrenaline-storing (NA) cells. The results indicate that sympathetic outflow to the adrenal gland, especially to A cells, is ceased or blocked during the adaptation to stress.
authors.affiliation: Department of Physiology, Niigata University, School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Hirano
authors.forename: K
authors.initials: K
authors.lastname: Nagai
authors.forename: T
authors.initials: T
authors.lastname: Bando
authors.forename: H
authors.initials: H
authors.lastname: Nakagawa
mesh_terms: D000311:Adrenal Glands / Q000378:metabolism* / Q000473:pathology; D000818:Animals; D001345:Autoradiography; D002838:Chromaffin System / Q000166:cytology / Q000378:metabolism* / Q000473:pathology; D003714:Denervation; D004298:Dopamine / Q000378:metabolism*; D005976:Glutaral; D006651:Histocytochemistry; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009993:Osmium Tetroxide; D012149:Restraint, Physical; D012834:Silver; D013315:Stress, Psychological / Q000378:metabolism* / Q000473:pathology
chemical_list: D012834:Silver; D009993:Osmium Tetroxide; D005976:Glutaral; D004298:Dopamine