title: [Pregnancy after direct oocyte-sperm transfer (DOST)--a simple alternative to in vitro fertilization (IVF)].
abstract: We report on the first pregnancies achieved at our clinic following direct oocyte-sperm-transfer (DOST). Immediately after follicular aspiration, oocytes together with spermatozoa prepared by the swim-up-technique are transferred to the uterus in a manner similar to the embryo transfer following IVF. Our study population consists of 9 patients with bilateral tubal occlusion, accompanied by a male factor in three cases. Up to now, we have achieved four pregnancies, including one twin pregnancy, all occurring, when a male factor was absent. The method described appears promising in terms of efficiency, reduction in the costs and technical procedures during treatment of human infertility.
authors.affiliation: Abt. Frauenheilkunde und Geburtshilfe, Universität Ulm.
authors.forename: K
authors.initials: K
authors.lastname: Sterzik
authors.forename: B
authors.initials: B
authors.lastname: Rosenbusch
authors.forename: D
authors.initials: D
authors.lastname: Grab
authors.forename: C
authors.initials: C
authors.lastname: Lauritzen
mesh_terms: D004624:Embryo Transfer / Q000379:methods; D005184:Fallopian Tube Diseases / Q000628:therapy*; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010063:Ovum / Q000637:transplantation*; D011247:Pregnancy; D013094:Spermatozoa / Q000637:transplantation*
vernacular_title: Schwangerschaften nach direktem Oozyten-Spermien-Transfer (DOST)--Eine einfache Alternative zur In-vitro-Fertilisation (IVF).