title: Hemorrhage associated with "bone crisis" in Gaucher's disease identified by magnetic resonance imaging.
abstract: Children suffering from Gaucher's disease were examined by magnetic resonance imaging (MRI) during a characteristic episode of "bone crisis". An unexpectedly high intramedullary as well as subperiosteal signal was observed on both the T1- and T2-weighted sequences in 5 patients, suggesting a subacute hemorrhage or hematoma. It is conceivable that such a painful hemorrhage is an important component of the "bone crisis" phenomenon. Furthermore, in these cases this is a specific sign which may enable differentiation of bone crises from other types of bone pain associated with Gaucher's disease.
authors.affiliation: Department of Pediatric Radiology, Beilinson Medical Center, School of Medicine, TA University, Petach-Tikva, Israel.
authors.forename: G
authors.initials: G
authors.lastname: Horev
authors.forename: L
authors.initials: L
authors.lastname: Kornreich
authors.forename: H
authors.initials: H
authors.lastname: Hadar
authors.forename: K
authors.initials: K
authors.lastname: Katz
mesh_terms: D000293:Adolescent; D001847:Bone Diseases / Q000175:diagnosis*; D002648:Child; D005260:Female; D005269:Femur / Q000473:pathology; D005776:Gaucher Disease / Q000150:complications* / Q000473:pathology; D006470:Hemorrhage / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013977:Tibia / Q000473:pathology