title: The evolution of Hodgkin's disease and necrobiotic xanthogranuloma syndrome.
abstract: We describe a woman in whom hypogammaglobulinemia and severe granulomatous cutaneous lesions had developed during childhood; subsequently, Hodgkin's disease and necrobiotic xanthogranuloma were diagnosed. This case illustrates an apparent association with disease activity and raises the question of a direct relationship of necrobiotic xanthogranuloma with lymphoproliferative disease.
authors.affiliation: Division of Hematology/Oncology, Mayo Clinic Scottsdale, AZ 85259.
authors.forename: C B
authors.initials: CB
authors.lastname: Reeder
authors.forename: S M
authors.initials: SM
authors.lastname: Connolly
authors.forename: R K
authors.initials: RK
authors.lastname: Winkelmann
mesh_terms: D000293:Adolescent; D000361:Agammaglobulinemia / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D001706:Biopsy; D001856:Bone Marrow Examination; D005260:Female; D006689:Hodgkin Disease / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D009367:Neoplasm Staging; D010265:Paraproteinemias / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D012008:Recurrence; D014057:Tomography, X-Ray Computed; D014972:Xanthogranuloma, Juvenile / Q000150:complications* / Q000175:diagnosis / Q000628:therapy