Effect of heavy drinking and alcohol withdrawal on markers of carbohydrate metabolism.
A number of biochemical markers were monitored in 38 male alcoholic patients at admittance and one week later. In patients with a drinking period of greater than 3 weeks the median fasting B-glucose decreased significantly as well as S-fructosamine concentrations. The ability of S-fructosamine to identify patients with a diabetic glucose tolerance test, expressed in terms of sensitivity and specificity, was 12 and 47%, respectively; that of HbA1c was still lower.
Kallner
A
A
Department of Clinical Chemistry, Karolinska Hospital, Stockholm, Sweden.
Blomquist
L
L
D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D001786:Blood Glucose / Q000032:analysis*; D000431:Ethanol / Q000009:adverse effects*; D019270:Fructosamine; D005951:Glucose Tolerance Test; D006442:Glycated Hemoglobin / Q000032:analysis*; D006595:Hexosamines / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013375:Substance Withdrawal Syndrome / Q000097:blood*; D013997:Time Factors
D015415:Biomarkers; D001786:Blood Glucose; D000431:Ethanol; D019270:Fructosamine; D006442:Glycated Hemoglobin; D006595:Hexosamines