Approaches to the evaluation of growth and growth disorders in children after bone marrow transplantation (BMT).
Since impaired growth may occur as a long--term consequence in children treated with BMT this aspect of development needs particular attention for various reasons. Primarily, in each affected child parameters relevant for the evaluation of growth need to be documented regularly from the beginning in a prospective mode. In addition, treatment protocols should contain elements of a standardized follow-up for the documentation and evaluation of the endocrine, the nutritional and the emotional situation of the patient. This will eventually allow us to define--and hopefully avoid--adverse elements within complex treatment modalities--including BMT--for various malignant diseases. Thus it will be possible to develop a rational approach for the therapy of persistent adverse events following attempts of treatment primarily directed to ensure survival.
Ranke
M B
MB
University Children's Hospital, Department of Hematology, Tübingen, FRG.
Dopfer
R
R
Blum
W F
WF
Niethammer
D
D
D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002648:Child; D005260:Female; D006128:Growth; D006130:Growth Disorders / Q000209:etiology* / Q000628:therapy; D006728:Hormones / Q000502:physiology; D006801:Humans; D008297:Male
D006728:Hormones