title: Subjective feelings and changes in body sway following diazepam in sons of alcoholics and control subjects.
abstract: The possible generalization to diazepam of the dampened response to ethanol in sons of alcoholic fathers was evaluated in 62 sons of alcoholics (family history positive [FHP] subjects) and 62 family history negative (FHN) controls (124 men). Following challenges with placebo, .12 and .2 mg/kg of diazepam in three separate sessions, evaluation of subjective feelings and increases in body sway revealed no decreased reaction for FHPs.
authors.affiliation: Alcohol Research Center, Veterans Affairs Medical Center, San Diego, California 92161.
authors.forename: M A
authors.initials: MA
authors.lastname: Schuckit
authors.forename: L A
authors.initials: LA
authors.lastname: Duthie
authors.forename: H I
authors.initials: HI
authors.lastname: Mahler
authors.forename: M
authors.initials: M
authors.lastname: Irwin
authors.forename: M G
authors.initials: MG
authors.lastname: Monteiro
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000235:genetics* / Q000523:psychology*; D000437:Alcoholism / Q000235:genetics* / Q000523:psychology*; D016241:Child of Impaired Parents / Q000523:psychology*; D003975:Diazepam / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D000431:Ethanol / Q000494:pharmacology; D006801:Humans; D008297:Male; D004856:Postural Balance / Q000187:drug effects*
chemical_list: D000431:Ethanol; D003975:Diazepam