title: Fine mapping of a human chromosome 6 ferritin heavy chain pseudogene: relevance to haemochromatosis.
abstract: We have used a somatic cell hybrid regional mapping panel for the short arm of chromosome 6, linkage analysis and a population study to map in detail a previously described ferritin heavy chain pseudogene sequence on chromosome 6. Our results show that this sequence maps to the short arm of chromosome 6 centromeric to the glyoxylase locus. The ferritin pseudogene locus is thus distant from the locus for the iron storage disease haemochromatosis, confirming previous evidence that this sequence is not a candidate for the haemochromatosis gene.
authors.affiliation: Department of Medicine, University of Queensland, Brisbane, Australia.
authors.forename: K M
authors.initials: KM
authors.lastname: Summers
authors.forename: K S
authors.initials: KS
authors.lastname: Tam
authors.forename: P B
authors.initials: PB
authors.lastname: Bartley
authors.forename: J
authors.initials: J
authors.lastname: Drysdale
authors.forename: H Y
authors.initials: HY
authors.lastname: Zoghbi
authors.forename: J W
authors.initials: JW
authors.lastname: Halliday
authors.forename: L W
authors.initials: LW
authors.lastname: Powell
mesh_terms: D002874:Chromosome Mapping; D002896:Chromosomes, Human, Pair 6; D015342:DNA Probes / Q000235:genetics; D005293:Ferritins / Q000235:genetics*; D008040:Genetic Linkage / Q000235:genetics*; D015235:HLA-B Antigens / Q000235:genetics; D006432:Hemochromatosis / Q000235:genetics*; D006801:Humans; D006822:Hybrid Cells; D011544:Pseudogenes / Q000235:genetics*
chemical_list: D015342:DNA Probes; D015235:HLA-B Antigens; D005293:Ferritins