Feasibility of semen collection and cryopreservation during chemotherapy.
Collection and cryopreservation of semen was undertaken in a 40-year-old man undergoing combination cyclophosphamide-doxorubicin-vincristine-prednisone chemotherapy for diffuse large cell lymphoma. Semen samples worthy of cryopreservation could be obtained through 39 days of therapy, with azoospermia observed after 70 days. Although pregnancy has not been attempted in the current case, reports by others suggest that normal outcomes can be expected with thawed semen collected during chemotherapy.
Carson
S A
SA
Department of Obstetrics and Gynecology, University of Tennessee, Memphis 38163.
Gentry
W L
WL
Smith
A L
AL
Buster
J E
JE
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D015925:Cryopreservation; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000188:drug therapy*; D008297:Male; D012662:Semen Preservation / Q000379:methods*; D013048:Specimen Handling / Q000379:methods*