title: Localization of outer surface proteins A and B in both the outer membrane and intracellular compartments of Borrelia burgdorferi.
abstract: Borrelia burgdorferi B31 with and without outer membranes contained nearly identical amounts of outer surface proteins A and B. The majority of each immunogen also was localized intracellularly by immunocryoultramicrotomy. These results are inconsistent with the widely held belief that outer surface proteins A and B are exclusively outer membrane proteins.
authors.affiliation: Department of Microbiology, Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas 75235.
authors.forename: J S
authors.initials: JS
authors.lastname: Brusca
authors.forename: A W
authors.initials: AW
authors.lastname: McDowall
authors.forename: M V
authors.initials: MV
authors.lastname: Norgard
authors.forename: J D
authors.initials: JD
authors.lastname: Radolf
mesh_terms: D001425:Bacterial Outer Membrane Proteins / Q000032:analysis*; D015748:Borrelia burgdorferi Group / Q000737:chemistry* / Q000648:ultrastructure; D002462:Cell Membrane / Q000737:chemistry / Q000648:ultrastructure; D007150:Immunohistochemistry; D008854:Microscopy, Electron
chemical_list: D001425:Bacterial Outer Membrane Proteins