title: Successful antibiotic therapy of clostridial septic arthritis in a patient with bilateral total hip prostheses.
abstract: We report a case of clostridial bacteraemia with infection of a prosthetic hip joint. The patient was successfully treated with IV benzyl penicillin and fucidin followed by oral amoxycillin and probenecid, without surgical intervention. She had no recurrence of her infection in the 19 months before her death. This is believed to be the first reported case of clostridial infection affecting a prosthetic joint.
authors.affiliation: Departments of Microbiology, University College Hospital, London, U.K.
authors.forename: C C
authors.initials: CC
authors.lastname: Kibbler
authors.forename: A M
authors.initials: AM
authors.lastname: Jackson
authors.forename: R N
authors.initials: RN
authors.lastname: Grüneberg
mesh_terms: D000368:Aged; D000658:Amoxicillin / Q000627:therapeutic use*; D001170:Arthritis, Infectious / Q000188:drug therapy*; D003015:Clostridium Infections / Q000188:drug therapy*; D003016:Clostridium perfringens / Q000302:isolation & purification; D005260:Female; D005672:Fusidic Acid / Q000627:therapeutic use*; D006622:Hip Prosthesis; D006801:Humans; D010400:Penicillin G / Q000627:therapeutic use*
chemical_list: D005672:Fusidic Acid; D000658:Amoxicillin; D010400:Penicillin G