[Effectiveness of human leukocytic interferon in children with papillomatosis of the larynx, trachea and bronchi].
The results of interferon therapy of 32 children with severe forms of laryngeal, tracheal, and bronchial papillomatosis are very encouraging. Clinical recovery (no relapses during 3 years or longer) was observed in 8 patients, improvement (no relapses during less than 3 years or 2-3-fold prolongation of no-relapse periods) was seen in 12 patients, no changes were recorded in 10 children; data on 2 other patients were too limited or lacking at all. The efficacy of interferon therapy of airways papillomatosis can be further increased, if doses are selected on an individual basis.
Chireshkin
D G
DG
Kuznetsov
V P
VP
Onufrieva
E K
EK
Pritsker
A D
AD
D000293:Adolescent; D001984:Bronchial Neoplasms / Q000209:etiology / Q000556:secondary / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D016898:Interferon-alpha / Q000008:administration & dosage*; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D010212:Papilloma / Q000473:pathology / Q000601:surgery*; D011182:Postoperative Care; D011300:Preoperative Care; D014134:Tracheal Neoplasms / Q000209:etiology / Q000556:secondary / Q000601:surgery*
D016898:Interferon-alpha
Effektivnost' chelovecheskogo leĭkotsitarnogo interferona pri papillomatoze gortani, trakheĭ i bronkhov u deteĭ.