The nucleotide and deduced amino acid sequence of the cationic 19 kDa outer membrane protein OmpH of Yersinia pseudotuberculosis.
The OmpH proteins of enteric bacteria are recently described, small (16 kDa), cationic outer membrane proteins. Because a Yersinia pseudotuberculosis cell envelope protein of this size has been found to cross-react serologically with the human histocompatibility antigen HLA-B27 (B*2701), the sequence of Y. pseudotuberculosis OmpH was determined by sequencing the gene region which encodes mature OmpH. A protein consisting of 143 amino acid residues was found. It was 96% homologous with the OmpH of Y. enterocolitica and 62% homologous with that of Escherichia coli. Two separate OmpH regions had sequence similarity with B*2701; they were identical in both Yersinia species.
Vuorio
R
R
Department of Bacteriology and Immunology, University of Helsinki, Finland.
Hirvas
L
L
Raybourne
R B
RB
Yu
D T
DT
Vaara
M
M
D000595:Amino Acid Sequence; D001425:Bacterial Outer Membrane Proteins / Q000737:chemistry / Q000235:genetics*; D001483:Base Sequence; D003001:Cloning, Molecular; D015796:HLA-B27 Antigen / Q000737:chemistry; D006801:Humans; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D015011:Yersinia pseudotuberculosis / Q000235:genetics*
D001425:Bacterial Outer Membrane Proteins; D015796:HLA-B27 Antigen; C067128:ompH protein, bacteria