title: Catheter with an anchoring tip for chronic joint capsule perfusion.
abstract: An orthopedic catheter for long-term access to the synovial joint is anchored by a hollow threaded tap that penetrates the capsule through a hole drilled in the surrounding bone. The proximal end of the catheter is connected to either an implantable drug infusion pump or an implantable access port for continuous or intermittent perfusion or sampling. Four catheters were evaluated in dogs. Three were attached to ports, the fourth to a pump. Water (one trial, 22 weeks) and hyaluronic acid (HA) (5 mg/ml; two trials of 8 weeks each) were administered through ports twice weekly in 1.5 ml boluses; 5 mg/ml HA was delivered by pump (1 trial of 33 weeks) at 0.31 ml/day.
authors.affiliation: Department of Surgery, University of Minnesota, Minneapolis 55455.
authors.forename: B D
authors.initials: BD
authors.lastname: Wigness
authors.forename: F D
authors.initials: FD
authors.lastname: Dorman
authors.forename: H J
authors.initials: HJ
authors.lastname: Robinson
authors.forename: E A
authors.initials: EA
authors.lastname: Arendt
authors.forename: T R
authors.initials: TR
authors.lastname: Oegema
authors.forename: T D
authors.initials: TD
authors.lastname: Rohde
authors.forename: H
authors.initials: H
authors.lastname: Buchwald
mesh_terms: D000818:Animals; D002408:Catheters, Indwelling; D004285:Dogs; D006820:Hyaluronic Acid / Q000008:administration & dosage; D015918:Infusion Pumps, Implantable; D007719:Knee Joint / Q000187:drug effects*; D013582:Synovial Fluid / Q000187:drug effects*
chemical_list: D006820:Hyaluronic Acid