title: The central nervous system in systemic lupus erythematosus.
abstract: Management of central nervous system (CNS) involvement is one of the most challenging problems in systemic lupus erythematosus. This article reviews the spectrum of CNS manifestations present in this disease, their diagnosis and pathogenesis, as well as an approach to their treatment and prognostic implications.
authors.affiliation: Lupus Arthritis Research Unit, Rayne Institute, St. Thomas' Hospital, London, UK.
authors.forename: M A
authors.initials: MA
authors.lastname: Khamashta
authors.forename: R
authors.initials: R
authors.lastname: Cervera
authors.forename: G R
authors.initials: GR
authors.lastname: Hughes
mesh_terms: D001927:Brain Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D015994:Incidence; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D001523:Mental Disorders / Q000209:etiology; D011379:Prognosis