[Results of assays of estrogen, progesterone and androgen receptors in stage I and II adenocarcinoma of the endometrium].
The prognosis for adenocarcinoma of the endometrium is dependent on the findings of the histopathological assessment of the tumor. In a retrospective study of patients treated in initially by surgery, the estrogen and progesterone receptors were assayed 89 times and the androgen receptors 64 times. No statistically significant correlation was found between any of these receptors and the degree of structural differentiation or degree of infiltration of the myometrium. The absence of any one of these receptors had no negative impact on the overall survival nor on recurrence-free survival. The same was true for the 9 tumors which were devoid of both estrogen and progesterone receptors. In the authors' experience, the results of these hormone assays did not provide any further information on which to base the prognosis of endometrial cancers.
Cormier
P
P
Fondation Bergonié, Centre Régional de Lutte Contre le Cancer de Bordeaux et du Sud-Ouest.
Floquet
A
A
Wafflart
J
J
Coindre
J M
JM
Bonichon
F
F
Marée
D
D
D000230:Adenocarcinoma / Q000737:chemistry* / Q000453:epidemiology / Q000473:pathology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D011237:Predictive Value of Tests; D011379:Prognosis; D011944:Receptors, Androgen / Q000737:chemistry*; D011960:Receptors, Estrogen / Q000737:chemistry*; D011980:Receptors, Progesterone / Q000737:chemistry*; D012189:Retrospective Studies; D015996:Survival Rate; D014594:Uterine Neoplasms / Q000737:chemistry* / Q000453:epidemiology / Q000473:pathology
D011944:Receptors, Androgen; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone
Résultats du dosage des récepteurs aux estrogènes, à la progestérone et aux androgènes dans les adénocarcinomes de l'endomètre aux stades cliniques I et II.