Measuring gastric PGE2 release in healthy and alcoholic subjects after ethanol stimulation.
The aim of this work was to study the effect of 20% and 40% ethanol, administered acutely, on gastric PGE2 release in normal subjects and alcoholics. Ethanol 20% did not modify the release of PGE2 into the gastric juice, whereas 40% ethanol increased PGE2 release only in healthy subjects. The basal PGE2 levels were higher in alcoholic patients.
Cavallini
G
G
Istituto di Clinica Medica, Università di Verona, Italy.
Franco
L
L
Brocco
G
G
Orlandi
P G
PG
Riela
A
A
Manara
P
P
Pavesi
V
V
Velo
G
G
D000328:Adult; D000437:Alcoholism / Q000378:metabolism*; D015232:Dinoprostone / Q000378:metabolism*; D000431:Ethanol / Q000494:pharmacology*; D005260:Female; D005750:Gastric Juice / Q000737:chemistry; D005753:Gastric Mucosa / Q000187:drug effects / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013268:Stimulation, Chemical
D000431:Ethanol; D015232:Dinoprostone