title: Fungal keratitis associated with contact lens wear after penetrating keratoplasty.
abstract: A 71-year-old patient had a stromal infiltration at the donor-recipient interface two years after penetrating keratoplasty while wearing a "piggyback-type" contact lens. The corneal graft sutures in the affected area had been removed one year previously. Corneal scraping revealed the presence of Candida parapsillosis, and the infection was treated successfully with a combination of amphotericin B and flucytosine. The association between contact-lens wear and fungal infections of corneal grafts is discussed.
authors.affiliation: Department of Ophthalmology, Beilinson Medical Center, Petah Tiqva, Israel.
authors.forename: I
authors.initials: I
authors.lastname: Kremer
authors.forename: M
authors.initials: M
authors.lastname: Goldenfeld
authors.forename: D
authors.initials: D
authors.lastname: Shmueli
mesh_terms: D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D002175:Candida / Q000187:drug effects / Q000302:isolation & purification; D002177:Candidiasis / Q000188:drug therapy / Q000209:etiology*; D003261:Contact Lenses / Q000009:adverse effects*; D003315:Cornea / Q000382:microbiology; D015821:Eye Infections, Fungal / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D005437:Flucytosine / Q000627:therapeutic use; D006801:Humans; D007634:Keratitis / Q000188:drug therapy / Q000382:microbiology*; D015948:Keratoplasty, Penetrating; D011183:Postoperative Complications
chemical_list: D000666:Amphotericin B; D005437:Flucytosine