Pathological study on cerebral amyloid angiopathy.
The cerebral amyloid angiopathy (CAA) was pathologically confirmed in 26 cases in which there were 20 cerebral hemorrhages, 2 subarachnoid hemorrhages, 3 cerebral infarctions, and 1 subdural hematoma. The CAA mainly involved the media and extima of small and medium-sized arteries as well as the capillaries of the brain tissue. Half of all cases in our series had the CAA associated vasculopathies (CAA-AV), including microaneurysms, "double barreling", onion skin-like intima, fibrinoid necrosis, clusters of arterioles and perivascular lymphocytic infiltrations. The CAA was often accompanied with the senile plaques and neurofibrillary tangles.
Xu
H Q
HQ
Department of Neurology, PLA General Hospital of the Shenyang Command.
Wang
Y S
YS
D000368:Aged; D016657:Cerebral Amyloid Angiopathy / Q000150:complications / Q000473:pathology*; D002536:Cerebral Arteries / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008576:Meningeal Arteries / Q000473:pathology; D008875:Middle Aged