Quadruple immunosuppression in renal allografts--the Auckland experience.
Recipients of live related and first cadaveric renal allografts were retrospectively reviewed before and after institution of a standardized regimen incorporating greater immunosuppression, (by the addition of antilymphocyte preparations). The two review groups were comparable with 11 live related and 27 first cadaver grafts in each. Despite a small advantage in terms of graft survival and diminished rejection, this was at the expense of septic morbidity. The implications of this are discussed.
Verran
D
D
Department of Surgery, Auckland Hospital.
Munn
S
S
Doak
P
P
Williams
L
L
Collins
J
J
Lee
W
W
D000961:Antilymphocyte Serum / Q000008:administration & dosage; D002102:Cadaver; D006084:Graft Rejection; D006085:Graft Survival; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods*; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016030:Kidney Transplantation / Q000401:mortality; D009520:New Zealand; D012189:Retrospective Studies; D014019:Tissue Donors
D000961:Antilymphocyte Serum; D007166:Immunosuppressive Agents