Further studies on acid phosphatase in obese subjects.
Low activity genetic variants of acid phosphatase (ACP1) are positively associated with extreme body mass deviations in obese subjects. The same pattern has been found in non-diabetic children, in diabetic pregnant women, and in non-diabetic adult subjects. Low activity variants of ACP1 also show a positive association with family history of obesity, supporting the hypothesis of an enhancing action of these variants on expressivity of obesity.
Paggi
A
A
Chair of Human Development, 2nd University of Rome School of Medicine, Italy.
Borgiani
P
P
Gloria-Bottini
F
F
Russo
S
S
Saponara
I
I
Banci
M
M
Amante
A
A
Lucarini
N
N
Bottini
E
E
D000135:Acid Phosphatase / Q000235:genetics*; D000328:Adult; D002648:Child; D005260:Female; D014644:Genetic Variation; D006801:Humans; D008297:Male; D009765:Obesity / Q000201:enzymology* / Q000235:genetics; D010641:Phenotype; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000201:enzymology / Q000235:genetics
D000135:Acid Phosphatase