Multi drug resistant Salmonella typhi infection: clinical profile and therapy.
Multiple drug resistant Salmonella typhi infection was observed in thirty five recent cases among forty eight children with bacteriologically proven enteric fever. Incidence of complications such as shock, myocarditis, encephalopathy and paralytic ileus was higher among these. A combination of cephalexin and gentamicin was successfully used in the management of these children.
Koul
P B
PB
Department of Pediatrics, University College of Medical Sciences, Delhi.
Murali
M V
MV
Sharma
P P
PP
Ghai
O P
OP
Ramchandran
V G
VG
Talwar
V
V
D000658:Amoxicillin / Q000494:pharmacology / Q000627:therapeutic use*; D002506:Cephalexin / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D002701:Chloramphenicol / Q000494:pharmacology / Q000627:therapeutic use*; D002702:Chloramphenicol Resistance; D004352:Drug Resistance, Microbial; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use*; D006801:Humans; D066298:In Vitro Techniques; D007194:India; D008297:Male; D012485:Salmonella typhi / Q000187:drug effects*; D014296:Trimethoprim Resistance; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000494:pharmacology / Q000627:therapeutic use*; D014435:Typhoid Fever / Q000188:drug therapy* / Q000382:microbiology
D005839:Gentamicins; D002701:Chloramphenicol; D000658:Amoxicillin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D002506:Cephalexin