[Endogenous vasoactive factors in children with nephrotic syndrome].
In accordance with the results of examining 40 children with nephrotic and mixed glomerulonephritis, it has been established that in the pathogenesis of the nephrotic syndrome of paramount importance is imbalance of the output of renal prostanoids, manifesting in the predominance of the vasopressor and proaggregate fraction--thromboxane A2 and in the deficiency of its antagonist prostacyclin that exerts a protective action on glomerular filtration. Sodium and water retention in patients with the nephrotic syndrome favours an increase of the content of antidiuretic hormone and plasma renin activity.
Tsygin
A N
AN
Kucherenko
A G
AG
Markov
Kh M
KhM
D015121:6-Ketoprostaglandin F1 alpha / Q000652:urine*; D002648:Child; D002940:Circadian Rhythm; D015237:Dinoprost / Q000652:urine*; D015232:Dinoprostone / Q000652:urine*; D006801:Humans; D009404:Nephrotic Syndrome / Q000503:physiopathology*; D012084:Renin-Angiotensin System / Q000502:physiology*; D013929:Thromboxane B2 / Q000652:urine*; D014667:Vasopressins / Q000097:blood*; D014882:Water-Electrolyte Balance / Q000502:physiology*
D014667:Vasopressins; D013929:Thromboxane B2; D015121:6-Ketoprostaglandin F1 alpha; D015237:Dinoprost; D015232:Dinoprostone
Endogennye vazoaktivnye faktory pri nefroticheskom sindrome u deteĭ.