title: Immune response of the Mongolian gerbil (Meriones unguiculatus) to sheep red blood cells.
abstract: The immune responses of Mongolian gerbils, Meriones unguiculatus, to sheep red blood cells (SRBC) were studied as compared to those of mice. After a single injection of SRBC, hemagglutinin titers in gerbils were significantly lower and hemolytic plaque-forming cells (PFC) in the spleen were less in number as compared to the response of mice. In gerbils the PFC response to a higher dose of bacterial lipopolysaccharide (LPS) was rather higher than in mice. The delayed-type hypersensitivity (DTH) assay on the foot-pad revealed that the responsiveness was considerably lower in gerbils than in mice.
authors.affiliation: Laboratory of Biomedical Science, College of Agriculture and Veterinary Medicine, Nihon University, Tsukuba, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Yukawa
authors.forename: T
authors.initials: T
authors.lastname: Onodera
authors.forename: K
authors.initials: K
authors.lastname: Yoshihara
authors.forename: H
authors.initials: H
authors.lastname: Saitoh
authors.forename: K
authors.initials: K
authors.lastname: Mochizuki
mesh_terms: D000818:Animals; D004912:Erythrocytes / Q000276:immunology*; D005849:Gerbillinae / Q000276:immunology*; D006386:Hemagglutination Tests; D006388:Hemagglutinins / Q000096:biosynthesis*; D006460:Hemolysin Proteins / Q000096:biosynthesis*; D006462:Hemolytic Plaque Technique; D006968:Hypersensitivity, Delayed / Q000662:veterinary*; D008297:Male; D012756:Sheep
chemical_list: D006388:Hemagglutinins; D006460:Hemolysin Proteins