[Age changes in the level of pyridinoline cross-linking and ratio of soluble and insoluble collagen in human rib collagen].
The changes in the content of mature crosslinks with pyridinoline structure and soluble/insoluble collagen ratio in the costal cartilage tissue of human beings aged from 1 month to 57 years were found to be age-dependent. The effect of the pyridinoline crosslink content on the soluble/insoluble collagen ratio in human costal cartilage tissue may constitute no less than 67% of the total influence of the sum of all factors. The pronounced nonlinearity of the studied dependencies points to a possible involvement of a factor(s) other than the pyridinoline crosslink content.
Prozorovskaia
N N
NN
Gorokhova
T A
TA
Muranov
S G
SG
Kozlov
E A
EA
Voronov
A V
AV
Del'vig
A A
AA
D000328:Adult; D000375:Aging / Q000378:metabolism*; D000596:Amino Acids / Q000378:metabolism*; D002356:Cartilage / Q000378:metabolism*; D003432:Cross-Linking Reagents; D006801:Humans; D007223:Infant; D008875:Middle Aged; D012272:Ribs; D012995:Solubility
D000596:Amino Acids; D003432:Cross-Linking Reagents; C015484:pyridinoline
Vozrastnye izmeneniia soderzhaniia piridinolinovykh sshivok i otnosheniia rastvorimogo i nerastvorimogo kollagena v rebernom khriashche cheloveka.