[Structure of nucleosomes. Localization of the H2A and H2B histone segments interacting with DNA using DNA-protein crosslinking].
Histones' H2A and H2B peptidic points which interact with nucleosomal DNA have been identified by using the methods of DNA--protein covalent cross-linking. H2B can be linked to DNA via its N-terminal tail and via several lysines contained within residues 24-34. The most prominent site of histone H2A covalent linking to DNA is His-123, the less prominent being Lys-119 and Lys-124.
Gushchin
D Iu
DIu
Ebralidze
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Mirzabekov
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D000595:Amino Acid Sequence; D000818:Animals; D002645:Chickens; D002851:Chromatography, High Pressure Liquid; D003432:Cross-Linking Reagents; D004247:DNA / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000378:metabolism*; D004591:Electrophoresis, Polyacrylamide Gel; D006657:Histones / Q000378:metabolism*; D006801:Humans; D008745:Methylation; D008969:Molecular Sequence Data; D009707:Nucleosomes / Q000378:metabolism; D014357:Trypsin
D003432:Cross-Linking Reagents; D004268:DNA-Binding Proteins; D006657:Histones; D009707:Nucleosomes; D004247:DNA; D014357:Trypsin
Struktura nukleosom. Lokalizatsiia vzaimodeĭstvuiushchikh s DNK uchstkov gistonov H2A i H2B s pomoshchĭu DNK-belkovykh sshivok.