title: The impact of vitamin A supplementation on morbidity: a randomized community intervention trial.
abstract: A randomized community trial investigated the impact of vitamin A supplementation on symptoms of respiratory and enteric infections among Indonesian children aged 1 to 5 years. A sample of 450 villages had been randomized into 229 villages that received vitamin A distribution and 221 that were observed as controls. The prevalence rates of cough, fever, and diarrhea were reduced in the treatment villages compared with the control villages by 8%, 5%, and 11%, respectively, but the reduction was not statistically significant. These results indicate that vitamin A supplements did not produce a substantial reduction in these symptoms, in spite of a reported reduction in all-cause mortality.
authors.affiliation: School of Public Health, University of Michigan, Ann Arbor 48109.
authors.forename: M H
authors.initials: MH
authors.lastname: Abdeljaber
authors.forename: A S
authors.initials: AS
authors.lastname: Monto
authors.forename: R L
authors.initials: RL
authors.lastname: Tilden
authors.forename: M A
authors.initials: MA
authors.lastname: Schork
authors.forename: I
authors.initials: I
authors.lastname: Tarwotjo
mesh_terms: D002675:Child, Preschool; D003371:Cough / Q000188:drug therapy* / Q000453:epidemiology / Q000517:prevention & control; D003967:Diarrhea / Q000188:drug therapy* / Q000453:epidemiology / Q000517:prevention & control; D005334:Fever / Q000188:drug therapy* / Q000453:epidemiology / Q000517:prevention & control; D006801:Humans; D007214:Indonesia / Q000453:epidemiology; D007223:Infant; D009017:Morbidity; D015995:Prevalence; D014801:Vitamin A / Q000008:administration & dosage / Q000627:therapeutic use*; D014985:Xerophthalmia / Q000453:epidemiology*
chemical_list: D014801:Vitamin A