Psychotic exacerbation attributed to low-dose bromocriptine treatment of galactorrhea and hyperprolactinemia.
Low-dose bromocriptine administered for antipsychotic drug-induced hyperprolactinemia and galactorrhea precipitated an acute psychotic state in a female patient. Discontinuation of the bromocriptine and increase in antipsychotic dosage resulted in complete remission. We advise caution in the use of bromocriptine especially in patients with a pre-existing psychiatric history and recommend monitoring for changes in mental status when bromocriptine is prescribed.
Dorevitch
A
A
Department of Obstetrics and Gynecology, Misgav Ladach General Hospital, Jerusalem, Israel.
Aronzon
R
R
Stark
M
M
D000208:Acute Disease; D000328:Adult; D001971:Bromocriptine / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D005687:Galactorrhea / Q000188:drug therapy*; D006801:Humans; D006966:Hyperprolactinemia / Q000188:drug therapy*; D011605:Psychoses, Substance-Induced / Q000209:etiology*; D012563:Schizophrenia, Paranoid / Q000188:drug therapy; D013881:Thioridazine / Q000627:therapeutic use
D001971:Bromocriptine; D013881:Thioridazine