title: [Stability of cefazolin sodium as eyedrops in various solutions].
abstract: Cephazolin sodium prepared with four different solutions (NaCl 0.9%, Protagent, Liquifilm and phosphate buffer) to be used as eye drops, was evaluated as to its physicochemical features at +4 degrees C, +37 degrees C and at room temperature and its activity in terms of minimal inhibition concentration. In conclusion, cephazolin sodium prepared with artificial tears at acidic pH can be kept for 3 days at room temperature and at +4 degrees C without any loss of its activity.
authors.affiliation: Anadolu Universitesi, Tip Fakültesi, Göz Hastaliklari Anabilim Dali Oğretim Uyesi.
authors.forename: N
authors.initials: N
authors.lastname: Yildirim
authors.forename: S
authors.initials: S
authors.lastname: Topbaş
authors.forename: G
authors.initials: G
authors.lastname: Usluer
authors.forename: I
authors.initials: I
authors.lastname: Ozgüneş
authors.forename: H
authors.initials: H
authors.lastname: Başmak
authors.forename: S
authors.initials: S
authors.lastname: Yurdakul
mesh_terms: D002021:Buffers; D002437:Cefazolin / Q000737:chemistry* / Q000494:pharmacology; D004355:Drug Stability; D006863:Hydrogen-Ion Concentration; D008826:Microbial Sensitivity Tests; D009883:Ophthalmic Solutions; D012996:Solutions; D013211:Staphylococcus aureus / Q000187:drug effects*; D013696:Temperature; D013997:Time Factors
chemical_list: D002021:Buffers; D009883:Ophthalmic Solutions; D012996:Solutions; D002437:Cefazolin
vernacular_title: Ceşitli sivilar ile göz damlasi olarak hazirlanan sefazolin sodyumun stabilitesi.