title: Antibody affinity and protection in virus infections.
abstract: Affinity of viral antibodies matures slowly after primary virus infections. Recent investigations with human sera and mouse monoclonal antibodies have provided the first evidence for a role of antibody affinity in the pathogenesis of chronic virus infections. More detailed studies are necessary before the rules and exceptions of this phenomenon are revealed.
authors.affiliation: University of Turku, Finland.
authors.forename: A A
authors.initials: AA
authors.lastname: Salmi
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D000915:Antibody Affinity; D006801:Humans; D007108:Immune Tolerance; D051379:Mice; D014777:Virus Diseases / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral