Correlation between 1.25 dihydroxyvitamin D serum levels and fractional rate of intestinal calcium absorption in hypercalciuric nephrolithiasis. Role of phosphate.
Different mechanisms could explain the elevated calcium elimination, the main cause of calcium oxalate renal stones. Our results suggest that phosphate levels are decreased in patients with absorptive hypercalciuric nephrolithiasis and elevated serum dihydroxyvitamin D. This could be the reason why in this group of patients oral phosphate treatment prevented hypercalciuria and renal lithiasis.
Alvarez-Arroyo
M V
MV
Laboratorio de la Unidad Metabólica, Fundación Jiménez Diaz, Spain.
Traba
M L
ML
Rapado
A
A
de la Piedra
C
C
Torralbo
M
M
D002117:Calcitriol / Q000097:blood*; D002118:Calcium / Q000378:metabolism*; D005260:Female; D006801:Humans; D007408:Intestinal Absorption / Q000502:physiology; D007669:Kidney Calculi / Q000097:blood / Q000737:chemistry* / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D010710:Phosphates / Q000378:metabolism* / Q000627:therapeutic use
D010710:Phosphates; D002117:Calcitriol; D002118:Calcium