Duplication of chromosome 11 centromere in fetal and maternal karyotypes: a new variant?
Fetal chromosome analysis in a 39-year-old mother revealed a chromosome 11 aberration interpreted as a duplication of the centromere. This was also found in the mother's karyotype, raising the possibility that the abnormality was a new variant of no clinical consequence.
Till
M
M
Laboratoire de Cytogénétique, Hôpital Edouard Herriot, Lyon, France.
Rafat
A
A
Charrin
C
C
Plauchu
H
H
Germain
D
D
D000328:Adult; D000649:Amniocentesis; D002503:Centromere / Q000648:ultrastructure*; D002869:Chromosome Aberrations / Q000175:diagnosis*; D002871:Chromosome Banding; D025063:Chromosome Disorders; D002880:Chromosomes, Human, Pair 11 / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D011247:Pregnancy