title: [Orthotopic liver transplantation--indications and results].
abstract: Indications for and results of orthotopic liver transplantation (OLT) were modified over the past ten years by new immunosuppressive agents, earlier timing of transplantation and better knowledge of potential complications. In 1990, OLT appears justified in the treatment of all liver disease threatening life, in the absence of contraindications and other possible treatments. Between July 1987 and December 1990, 21 patients were transplanted at the Geneva University Hospital. Three children received part of an adult liver (two or three segments), using the reduced-size liver transplantation technique. Four OLTs had to be performed in an emergency situation. Two patients died within six months of transplantation, one after 7.5 months, and the last patient died after one year from cancer recurrence. 17 patients are presently alive (81%) at 4 to 39 months (median 14 months) following OLT. More than the mere survival, however, the quality of life regained after transplantation prompts us to consider transplantation early in the progress of the disease.
authors.affiliation: Clinique de chirurgie digestive, Hôpital cantonal universitaire, Genève.
authors.forename: G
authors.initials: G
authors.lastname: Mentha
authors.forename: C
authors.initials: C
authors.lastname: Le Coultre
authors.forename: O
authors.initials: O
authors.lastname: Huber
authors.forename: P
authors.initials: P
authors.lastname: Meyer
authors.forename: D
authors.initials: D
authors.lastname: Belli
authors.forename: C
authors.initials: C
authors.lastname: Klopfenstein
authors.forename: M
authors.initials: M
authors.lastname: Kowalski
authors.forename: A
authors.initials: A
authors.lastname: Rohner
mesh_terms: D000293:Adolescent; D000328:Adult; D001656:Biliary Atresia / Q000601:surgery; D006502:Budd-Chiari Syndrome / Q000601:surgery; D002675:Child, Preschool; D015209:Cholangitis, Sclerosing / Q000601:surgery; D005260:Female; D006505:Hepatitis / Q000601:surgery; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000601:surgery; D008105:Liver Cirrhosis, Biliary / Q000601:surgery; D008107:Liver Diseases / Q000601:surgery*; D008113:Liver Neoplasms / Q000601:surgery; D016031:Liver Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged
vernacular_title: Orthotope Lebertransplantation--Indikationen und Resultate.