title: Histological evolution of peripheral T-cell lymphomas. Study of six cases.
abstract: The authors report 6 cases of histological transformation in peripheral T-cell lymphomas of low grade of malignancy. The transformation occurs in 75% of the cases, in extra-nodal sites and corresponds to a monomorphic of pleiomorphic large cell type. There is no discordance in the immunologic results between the two phases. The transformation seems to occur earlier than in B lymphomas, with a relative frequency of hematological manifestations and no therapeutic response.
authors.affiliation: Institut Paoli-Calmettes, Marseille, France.
authors.forename: N
authors.initials: N
authors.lastname: Horschowski
authors.forename: D
authors.initials: D
authors.lastname: Sainty
authors.forename: G
authors.initials: G
authors.lastname: Sebahoun
authors.forename: F
authors.initials: F
authors.lastname: George
authors.forename: R
authors.initials: R
authors.lastname: Bouabdallah
authors.forename: A M
authors.initials: AM
authors.lastname: Stoppa
authors.forename: D
authors.initials: D
authors.lastname: Maraninchi
authors.forename: D
authors.initials: D
authors.lastname: Blaise
authors.forename: Y
authors.initials: Y
authors.lastname: Carcassonne
mesh_terms: D000368:Aged; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D005260:Female; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology / Q000503:physiopathology; D016411:Lymphoma, T-Cell, Peripheral / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged