title: Orofacial and respiratory tardive dyskinesia: potential side effects of 2-dimethylaminoethanol (deanol)?
abstract: A case of essential tremor since early adultness is presented, which has been treated successfully with the acetylcholine precursor 2-dimethylaminoethanol (deanol) for 10 years. Development of a marked dyskinesia syndrome affecting predominantly orofacial and respiratory musculature has been noticed with this medication. Partial remission after discontinuation and a favorable response to anticholinergics are suggestive of an adverse drug effect.
authors.affiliation: Department of Neurology, University of Göttingen, FRG.
authors.forename: B A
authors.initials: BA
authors.lastname: Haug
authors.forename: M
authors.initials: M
authors.lastname: Holzgraefe
mesh_terms: D003642:Deanol / Q000008:administration & dosage / Q000009:adverse effects*; D003937:Diagnosis, Differential; D004409:Dyskinesia, Drug-Induced / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009460:Neurologic Examination; D012132:Respiratory Muscles / Q000187:drug effects*; D013375:Substance Withdrawal Syndrome / Q000175:diagnosis / Q000209:etiology; D014202:Tremor / Q000188:drug therapy*
chemical_list: D003642:Deanol