title: [Immunosuppressive drugs and autoimmune diseases].
abstract: Only a few immunosuppressive drugs can be used today. These are: corticosteroids, azathioprine, cyclophosphamide, ciclosporine A, accessorily chlorambucil and methotrexate. They all have different actions on immune responses. The use of these drugs has completely changed the prognosis of autoimmune diseases such as systematic lupus erythematous, polyartheritis nodosa, Wegener's granulomatosis. Nevertheless treatment of other autoimmune diseases, such as type I insulin-dependent diabetes mellitus or multiple sclerosis, has been inconclusive.
authors.affiliation: INSERM U 28, Hôpital Broussais, Paris.
authors.forename: J
authors.initials: J
authors.lastname: Rossert
authors.forename: P
authors.initials: P
authors.lastname: Druet
mesh_terms: D001327:Autoimmune Diseases / Q000188:drug therapy*; D006801:Humans; D007109:Immunity / Q000187:drug effects; D007166:Immunosuppressive Agents / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D007166:Immunosuppressive Agents
vernacular_title: Immunosuppresseurs chimiques et maladies auto-immunes.