Effect of treatment and noncompliance on post-polio sequelae.
In this study of 77 patients with post-polio sequelae (PPS), symptoms and manual test scores on initial evaluation were compared with those at subsequent follow-up evaluations. Patients were divided into three groups based on the degree to which they had complied with clinically recommended interventions: compliers, partial compliers, and noncompliers. At the end of the follow-up period (2.2 +/- 1.2 years), the mean muscle function scores of the entire study group had declined -1.5%, which represented a decline of -0.7% annually. On follow-up evaluations, the complier group had realized an improvement or resolution of post-polio symptoms, and also an improvement in muscle function of +0.6% annually. The partial complier group had realized either no improvement, or improvement in post-polio symptoms, but showed a further decline in muscle function of -3.0%, or an annual decline of -1.3%. The noncomplier group showed either no change, or a worsening of post-polio symptoms, and also showed a further decline in muscle function of -4.1%, which represented an annual decline of -2.0%.
Peach
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PE
Roosevelt Warm Springs Institute for Rehabilitation, Georgia 31830.
Olejnik
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D000328:Adult; D005221:Fatigue / Q000503:physiopathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009119:Muscle Contraction; D009123:Muscle Hypotonia / Q000503:physiopathology; D010349:Patient Compliance; D016262:Postpoliomyelitis Syndrome / Q000523:psychology / Q000534:rehabilitation*