Measurement of interleukin 1 alpha and 1 beta (IL-1 alpha and IL-1 beta) in human cystic lesions of the jaw. Implications for the pathogenesis of radicular cysts.
Human radicular cystic tissue of jaws was found to contain between 0.823 pg/mg to 18.026 pg/mg interleukin 1 beta and from 0.34 pg/mg to 0.708 pg/mg interleukin 1 alpha. No IL-1 beta and alpha could be found in specimens from healthy patients. A finding which may be extremely relevant in cystic growth and episodes of alveolar bone resorption around the cystic lesion.
Hoenig
J F
JF
Department of Maxillo-Facial-Surgery, University Hospital, Goettingen, Germany.
Rordorf-Adam
C
C
Siegmund
C
C
Erard
F
F
D000911:Antibodies, Monoclonal; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006801:Humans; D007375:Interleukin-1 / Q000032:analysis*; D011842:Radicular Cyst / Q000737:chemistry* / Q000209:etiology
D000911:Antibodies, Monoclonal; D007375:Interleukin-1