Primary structure of the embryo-expressed gene KE2 from the mouse H-2K region.
Nucleotide (nt) sequence of the KE2 wild-type (wt) cDNA revealed a novel 669-bp open reading frame encoding a putative hydrophilic protein of 127 amino acids, pI 6.17. Comparison of the wt to the genomic nt sequence from the tw5 mutant shows the KE2 gene is conserved and is probably a functional gene unrelated to the tw5 lethality.
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Department of Zoology, University of Texas, Austin 78712-1064.
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D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003360:Cosmids / Q000235:genetics; D004268:DNA-Binding Proteins; D004622:Embryo, Mammalian / Q000378:metabolism; D005091:Exons / Q000235:genetics; D015870:Gene Expression / Q000235:genetics; D005805:Genes, MHC Class I; D006649:Histocompatibility Antigens / Q000235:genetics*; D047908:Intracellular Signaling Peptides and Proteins; D007438:Introns / Q000235:genetics; D008285:Major Histocompatibility Complex; D051379:Mice; D008869:Microtubule-Associated Proteins; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics; D009687:Nuclear Proteins / Q000235:genetics*; D016366:Open Reading Frames / Q000235:genetics; D016133:Polymerase Chain Reaction; D044767:Ubiquitin-Protein Ligases; D056427:t-Complex Genome Region
D004268:DNA-Binding Proteins; D006649:Histocompatibility Antigens; D047908:Intracellular Signaling Peptides and Proteins; D008869:Microtubule-Associated Proteins; D009687:Nuclear Proteins; C072003:Pfdn6 protein, mouse; C116196:PPP1R11 protein, human; D044767:Ubiquitin-Protein Ligases