Sclerotic fibromas of the skin.
We report a case of a 34-year-old Japanese woman with a fibrous tumor on the left palm that fulfilled the criteria of sclerotic fibroma of the skin. Immunohistochemically, the tumor cells were positive for vimentin, but negative for S-100 protein and neuron-specific enolase. Ultrastructurally, the cross-striations of collagen microfibrils were less prominent. Our case supports the concept that sclerotic fibroma of the skin is a distinctive lesion which may represent a hamartoma of the skin.
Nogita
T
T
Department of Dermatology, Tokyo Women's Medical College, Japan.
Akiyoshi
E
E
Kawashima
M
M
D000328:Adult; D003094:Collagen / Q000648:ultrastructure; D003937:Diagnosis, Differential; D005260:Female; D005350:Fibroma / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D008854:Microscopy, Electron; D012598:Sclerosis; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D014746:Vimentin / Q000032:analysis
D014746:Vimentin; D003094:Collagen