title: Cytogenetic analysis of two sacral chordomas.
abstract: Cytogenetic analysis of two sacral chordomas revealed two distinct abnormal clones in one of the cases: 44,XY,t(1;3)(q42;q11), -2,der(7)t(2;7)(q23;q32), -21 and 46,X,t(Y;8)(q12;q22), t(1;14)(p34;q32),t(5;10)(q13;p11). All cells analyzed from the second case were cytogenetically normal. To the best of our knowledge, chordomas have not previously been subjected to cytogenetic analysis.
authors.affiliation: Department of Pathology and Oncology, University of Kansas Medical Center.
authors.forename: D L
authors.initials: DL
authors.lastname: Persons
authors.forename: J A
authors.initials: JA
authors.lastname: Bridge
authors.forename: J R
authors.initials: JR
authors.lastname: Neff
mesh_terms: D000368:Aged; D001859:Bone Neoplasms / Q000235:genetics*; D002817:Chordoma / Q000235:genetics*; D002877:Chromosomes, Human; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012447:Sacrum; D014178:Translocation, Genetic; D014998:Y Chromosome