Primary pulmonary hypertension and human immunodeficiency virus infection in a non-hemophiliac man.
We describe clinical and postmortem findings in a 44-year-old man with pulmonary hypertension and infection with the human immunodeficiency virus (HIV-1). Plexogenic angiopathy and veno-occlusive lesions were present, in addition to a mild, patchy pulmonary interstitial lymphoid infiltrate. The clinical data for 14 previously reported cases of HIV-associated primary pulmonary hypertension are summarized. We speculate that these vascular changes may be due to damage from a specific immune response to HIV.
Jacques
C
C
Anatomic Pathology Service, Department of Veterans Affairs Medical Center, San Francisco, CA.
Richmond
G
G
Tierney
L
L
Curtis
J L
JL
McKerrow
J
J
Warnock
M L
ML
D000328:Adult; D001344:Autopsy; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications* / Q000473:pathology*; D008297:Male