Long term follow-up after surgical removal of pheochromocytoma--observations in 61 patients.
89 patients were operated on for pheochromocytoma. 61 patients (37 women and 24 men) were available for extended follow-up. The final survey, performed 79.1 +/- 66.9 months postoperatively, provided data on survival, blood pressure tumor recurrence, malignant metastatic lesions, cardiovascular complications and coexisting diseases. There were 4 deaths during the follow-up period, including 2 instances of malignant pheochromocytoma. Permanent normalization of blood pressure was achieved in 38 patients (62.3%). This hypotensive effect was noted in 79.2% of patients with preoperative paroxysmal hypertension and in 40.8% of those with sustained hypertension. Permanent or re-developing postoperative hypertension was noted in 23 (37.7%) patients. This includes 4 cases of malignant pheochromocytoma, 4 cases of recurrent benign pheochromocytoma and 15 cases of essential hypertension. Cardiovascular complications during follow-up were rare and concerned the patients with essential hypertension diagnosed postoperatively.
Pruszczyk
P
P
Department of Hypertension and Angiology, Medical Academy, Warsaw.
Januszewicz
W
W
Feltynowski
T
T
Chodakowska
J
J
Wocial
B
B
Pachocki
R
R
Nielubowicz
J
J
Szostek
M
M
D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D001794:Blood Pressure; D002318:Cardiovascular Diseases / Q000209:etiology; D002395:Catecholamines / Q000652:urine; D003920:Diabetes Mellitus / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000209:etiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010673:Pheochromocytoma / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D011379:Prognosis
D002395:Catecholamines