title: Subcutaneous leiomyosarcoma developing in a radiation dermatitis.
abstract: A case of subcutaneous leiomyosarcoma developing in a skin affected by radiation dermatitis is presented. A 59-year-old patient had been suffering from radiation dermatitis induced by radiotherapy for a mediastinal tumor diagnosed at 24 years of age. Thirty-four years later, slow growing nodules developed in this lesion. Light and electron microscopic studies revealed that the tumor was a subcutaneous leiomyosarcoma. There is no previous report of a subcutaneous leiomyosarcoma developing in radiation dermatitis.
authors.affiliation: Department of Dermatology, Osaka University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yamamura
authors.forename: A
authors.initials: A
authors.lastname: Takada
authors.forename: M
authors.initials: M
authors.lastname: Higashiyama
authors.forename: K
authors.initials: K
authors.lastname: Yoshikawa
mesh_terms: D003872:Dermatitis / Q000150:complications* / Q000209:etiology; D006801:Humans; D007890:Leiomyosarcoma / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D008297:Male; D008479:Mediastinal Neoplasms / Q000532:radiotherapy*; D008875:Middle Aged; D011878:Radiotherapy / Q000009:adverse effects*; D012878:Skin Neoplasms / Q000209:etiology / Q000473:pathology* / Q000601:surgery