title: Chronic lesions of thrombo-embolic meningo-encephalomyelitis in calves.
abstract: Six calves showed neurological signs with recumbency for 5 to 30 days. Histologically, they had encephalomyelitis characterized by multiple minute foci of malacia and perivascular microgliosis throughout the central nervous system. Widespread degeneration of the white matter was also detected mainly in the spinal cord. Micro-abscesses and thrombophlebitis, which were occasionally observed in the malacic lesions, suggested that the disease was a feature of infectious thrombo-embolic meningo-encephalomyelitis modified by various factors, including antibiotic therapy.
authors.affiliation: Department of Comparative Pathology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Yamasaki
authors.forename: T
authors.initials: T
authors.lastname: Umemura
authors.forename: M
authors.initials: M
authors.lastname: Goryo
authors.forename: C
authors.initials: C
authors.lastname: Itakura
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology / Q000473:pathology*; D002490:Central Nervous System / Q000473:pathology; D002908:Chronic Disease; D004678:Encephalomalacia / Q000382:microbiology / Q000473:pathology / Q000662:veterinary; D004679:Encephalomyelitis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D006190:Haemophilus / Q000276:immunology; D006192:Haemophilus Infections / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D008590:Meningoencephalitis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D013923:Thromboembolism / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*
chemical_list: D000907:Antibodies, Bacterial