Cytogenetic study of a papillary thyroid carcinoma with a rearranged chromosome 10.
Cytogenetic findings of a multifocal papillary thyroid cancer and a metastatic lymph node from a 29-year-old white female patient are reported. Two clonal aberrations were observed: a trisomy 7 in one nodule, and a rearranged chromosome 10 in a separate nodule and in a lymph node. The rearrangement of 10q described here is similar to other published cases and is relevant for interpreting the molecular findings associated with thyroid cancer.
Herrmann
M E
ME
Michigan Cancer Foundation, Detroit.
Mohamed
A
A
Talpos
G
G
Wolman
S R
SR
D000328:Adult; D002291:Carcinoma, Papillary / Q000473:pathology*; D002879:Chromosomes, Human, Pair 10; D002897:Chromosomes, Human, Pair 7; D002999:Clone Cells; D005260:Female; D006801:Humans; D007621:Karyotyping; D008207:Lymphatic Metastasis; D013964:Thyroid Neoplasms / Q000473:pathology*; D014314:Trisomy