A multicenter study of short hour dialysis using AN69S. Preliminary results.
A multicenter prospective study of short hour (SH, less than or equal to 3 hr) dialysis using a high flux membrane (AN69S) plus volumetric control (VC), versus conventional (greater than or equal to 4 hr) (CNV) cellulosic non-VC dialysis, is ongoing. The study hypothesizes that SH treatment over 1 year will provide adequate dialysis, will not increase morbidity, and may improve quality of life. To date, 112 patients have been entered, and 54 have completed 6 months, 30 by SH. There were no differences in biophysiologic parameters at 6 months. Mean hospitalization was 5.24 days per patient. The SH group had a higher (p = 0.0374) hospitalization rate because of two patients. Quality of life was similar in SH and CNV groups. The study indicates that SH dialysis is feasible, safe, and as comfortable as CNV.
Lindsay
R M
RM
Department of Medicine, Victoria Hospital, London, Ontario, Canada.
Spanner
E
E
Heidenheim
A P
AP
Burton
H
H
Lindsay
S
S
LeFebvre
J M
JM
D000180:Acrylic Resins; D000181:Acrylonitrile / Q000031:analogs & derivatives*; D000328:Adult; D002482:Cellulose; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000628:therapy*; D007688:Kidneys, Artificial; D008567:Membranes, Artificial; D011188:Potassium / Q000097:blood; D011788:Quality of Life; D013997:Time Factors; D014508:Urea / Q000097:blood
D000180:Acrylic Resins; D008567:Membranes, Artificial; C016892:AN-69; D014508:Urea; D002482:Cellulose; D000181:Acrylonitrile; D011188:Potassium