Cytogenetic analysis of the mature and immature teratoma components of a metastatic testicular nonseminomatous germ cell tumor.
A case is described in which the mature and immature teratoma components of metastases of the same testicular nonseminomatous germ cell tumor were karyotyped. The highly similar karyotypes of both components suggest that the phenotypic difference is predominantly epigenetically determined.
de Graaff
W E
WE
Department of Pathology, University of Groningen, The Netherlands.
de Jong
B
B
Oosterhuis
J W
JW
van Echten-Arends
J
J
Wiersema-Buist
J
J
Schraffordt Koops
H
H
Sleijfer
D T
DT
D000328:Adult; D002869:Chromosome Aberrations / Q000473:pathology; D025063:Chromosome Disorders; D004273:DNA, Neoplasm / Q000032:analysis; D006801:Humans; D007621:Karyotyping; D008297:Male; D009362:Neoplasm Metastasis; D013724:Teratoma / Q000235:genetics / Q000473:pathology*; D013736:Testicular Neoplasms / Q000235:genetics / Q000473:pathology*
D004273:DNA, Neoplasm