Elementary methods of cohort analysis with several exposure levels.
This paper proposes an extension of the Mantel-Haenszel rate ratio for the dichotomous exposure to the multiple exposure levels. This extension is based on the unbiased estimating function approach and yields closed-form Mantel-Haenszel rate ratio estimators. Dually consistent variance and covariance estimators of the estimating functions are given and a quasi-score-based confidence interval for individual common rate ratio is provided. A similar extension to the common rate difference case is also given.
Sato
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Department of Epidemiology, School of Health Sciences, University of Tokyo, Japan.
D020261:Arsenic Poisoning; D015331:Cohort Studies; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology / Q000209:etiology*; D008433:Mathematics; D009009:Montana; D016273:Occupational Exposure; D016017:Odds Ratio; D016012:Poisson Distribution; D012142:Respiratory Tract Neoplasms / Q000139:chemically induced* / Q000453:epidemiology; D012907:Smoking / Q000009:adverse effects*; D006113:United Kingdom