title: Enterosorption in oncotherapy.
abstract: Patients with lymphogranulomatosis undergoing radiotherapy according to the radical scheme were treated with fibrous carbon enterosorbent VESTA in tablets for 14 days (group I, 23 patients) from the moment of leukopenia development (lower then 2.2 x 10(9)/l) or were traditionally treated using parenteral administration of hemostimulants, hemosubstitutes and detoxicants (group II, 23 patients). After 14 days leukopenia was cured in 18 patients of group I (78%) and in 11 patients of group II (48%), with an average number of leukocytes in the patients of groups I and II growing by 2 and 1.6 times, respectively. The administration of enterosorbents enabled interruptions in radiotherapy caused by the development of leukopenia and the deterioration of health status to be greatly shortened and the requirements in expensive transfusion media to be sharply reduced.
authors.affiliation: Research Institute of Oncology and Medical Radiology, Byelorussian SSR, Minsk, USSR.
authors.forename: G V
authors.initials: GV
authors.lastname: Muravskaya
authors.forename: V G
authors.initials: VG
authors.lastname: Nikolaev
authors.forename: V P
authors.initials: VP
authors.lastname: Sergeev
authors.forename: N I
authors.initials: NI
authors.lastname: Krutilina
authors.forename: L V
authors.initials: LV
authors.lastname: Bonatskaya
authors.forename: V N
authors.initials: VN
authors.lastname: Klevtsov
authors.forename: V V
authors.initials: VV
authors.lastname: Surovikina
authors.forename: V V
authors.initials: VV
authors.lastname: Sinajko
mesh_terms: D000328:Adult; D002244:Carbon; D016061:Enterosorption; D005260:Female; D006689:Hodgkin Disease / Q000532:radiotherapy; D006801:Humans; D007970:Leukopenia / Q000209:etiology / Q000628:therapy*; D008297:Male; D011878:Radiotherapy / Q000009:adverse effects
chemical_list: D002244:Carbon