title: Flumazenil for the reversal of refractory benzodiazepine-induced shock.
abstract: Benzodiazepines are known to cause central nervous system and centrally mediated cardiovascular depression. The benzodiazepine antagonist flumazenil has been shown to antagonize benzodiazepine-induced central nervous system depression. We report a case in which cardiovascular depression secondary to benzodiazepine use was reversed by this agent.
authors.affiliation: Division of Emergency Medicine, Allegheny General Hospital, Pittsburgh, PA 15212.
authors.forename: W
authors.initials: W
authors.lastname: Coates
authors.forename: T C
authors.initials: TC
authors.lastname: Evans
authors.forename: D
authors.initials: D
authors.lastname: Jehle
authors.forename: F
authors.initials: F
authors.lastname: Harchelroad
authors.forename: M
authors.initials: M
authors.lastname: Isaacs
mesh_terms: D000368:Aged; D002319:Cardiovascular System / Q000187:drug effects; D002490:Central Nervous System / Q000187:drug effects; D003975:Diazepam / Q000009:adverse effects* / Q000037:antagonists & inhibitors / Q000627:therapeutic use; D005260:Female; D005442:Flumazenil / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D012119:Respiration / Q000187:drug effects; D012769:Shock / Q000139:chemically induced* / Q000188:drug therapy
chemical_list: D005442:Flumazenil; D003975:Diazepam