The systemic and genetic significance of congenital optic disc anomalies.
Optic disc anomalies have great significance as a clue to associated systemic problems and as a marker of inherited disease. Optic nerve hypoplasia and colobomas of the optic disc are the main visually significant disorders; however, the Morning Glory disc anomaly and Aicardi's syndrome may also be associated with visual impairment.
Jacobs
M
M
Hospital for Sick Children, London.
Taylor
D
D
D003103:Coloboma / Q000235:genetics*; D006801:Humans; D009896:Optic Atrophy / Q000150:complications / Q000235:genetics*; D009898:Optic Disk / Q000002:abnormalities*; D009900:Optic Nerve / Q000002:abnormalities; D014786:Vision Disorders / Q000209:etiology