title: [Immunochemical tests in the diagnosis of diseases of the male reproductive system].
abstract: Immunochemical tests were employed to measure proteins (acid phosphatase, prostatic beta-globulin, endometrial alpha-2-globulin, lactoferrin, carcinoembryonal antigen) in spermatic plasma and prostatic fluid from healthy subjects and patients with prostatic adenoma, cancer, chronic inflammation, defects of spermatogenesis. It was found that the overall concentration of acid phosphatase and prostatic beta-globulin may serve a diagnostic criteria to differentiate prostatic adenoma from cancer as in 93% of prostatic cancer this parameter did not exceed 400 micrograms/ml whereas in 75% of adenomas it was above 1200 micrograms/ml. Activity of chronic prostatitis can be assessed from lactoferrin test. The level of the organ-specific antigens (acid phosphatase and prostatic beta-globulin) and lactoferrin correlated with the severity of spermatogenesis disorders.
authors.forename: A A
authors.initials: AA
authors.lastname: Nikolaev
authors.forename: N I
authors.initials: NI
authors.lastname: Anshakova
authors.forename: V M
authors.initials: VM
authors.lastname: Mel'man
mesh_terms: D003937:Diagnosis, Differential; D005832:Genital Diseases, Male / Q000175:diagnosis* / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D007159:Immunologic Tests; D008297:Male; D011467:Prostate / Q000378:metabolism; D029584:Prostatic Secretory Proteins; D011506:Proteins / Q000032:analysis / Q000378:metabolism; D012661:Semen / Q000737:chemistry / Q000378:metabolism; D029589:Seminal Plasma Proteins
chemical_list: D029584:Prostatic Secretory Proteins; D011506:Proteins; D029589:Seminal Plasma Proteins; C043076:beta-microseminoprotein
vernacular_title: Immunokhimicheskie testy v diagnostike zabolevaniĭ muzhskoĭ reproduktivnoĭ sistemy.