[Effect of diltiazem on silent myocardial ischemia].
Thirty-four patients with coronary heart disease who had silent myocardiac ischemic episodes as evidenced by long-term ECG monitoring were examined. Silent ST-segment elevations and depressions were encountered 2.7- and 4.9-fold as compared to manifest ones. The fact that the CHD patients had silent ST-segment depressions and/or prolonged high-amplitude silent ST-segment elevations suggests a grave severity of abnormal myocardial processes. There was a reduction in the number, duration of silent ST-segment elevations and depression episodes and in the amplitude of silent ST-segment depressions. This may indirectly indicate that the agent affects predominantly coronary blood flow and coronary vascular tone.
Zharov
E I
EI
Galichenko
I V
IV
Martynov
A I
AI
Vertkin
A L
AL
Styrova
T K
TK
D000328:Adult; D000368:Aged; D003327:Coronary Disease / Q000188:drug therapy*; D004110:Diltiazem / Q000494:pharmacology*; D004562:Electrocardiography / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged
D004110:Diltiazem
Vliianie diltiazema na bezbolevuiu ishemiiu miokarda.