Ribosomal protein S14 is not responsible for the Minute phenotype associated with the M(1)7C locus in Drosophila melanogaster.
A locus associated with a severe Minute effect has been mapped at 7C on the X chromosome of Drosophila melanogaster. Previous work has suggested that this Minute encodes ribosomal proteins S14A and S14B. We have made a chromosomal deficiency that removes the S14 ribosomal protein genes, yet does not display the Minute phenotype. These data suggest that the S14 genes do not actually correspond to the Minute locus.
Dorer
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DR
Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107.
Anane-Firempong
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A
Christensen
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AC
D000818:Animals; D002871:Chromosome Banding; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D004247:DNA / Q000235:genetics; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D007621:Karyotyping; D008297:Male; D016296:Mutagenesis; D009693:Nucleic Acid Hybridization; D010641:Phenotype; D012269:Ribosomal Proteins / Q000235:genetics*; D014960:X Chromosome
D012269:Ribosomal Proteins; C039747:ribosomal protein S14; D004247:DNA