The stability of four catecholamines in 5% glucose infusions.
The stability of adrenaline, noradrenaline, dopamine and dobutamine in 5% glucose infusion minibags stored at 5 degrees C was determined. Results indicated that noradrenaline (16 and 40 mg/l) and dobutamine (1 and 5 g/l) were relatively stable with t/95% values in excess of 30 days. Adrenaline and dopamine were less stable. The t/95% values were approximately 20 and 14 days respectively.
Allwood
M C
MC
Medicines Research Unit, Derbyshire Royal Infirmary, U.K.
D002395:Catecholamines / Q000008:administration & dosage / Q000737:chemistry*; D002626:Chemistry, Pharmaceutical; D004280:Dobutamine / Q000008:administration & dosage / Q000737:chemistry; D004298:Dopamine / Q000008:administration & dosage / Q000737:chemistry; D004355:Drug Stability; D004837:Epinephrine / Q000008:administration & dosage / Q000737:chemistry; D005947:Glucose / Q000737:chemistry*; D009638:Norepinephrine / Q000008:administration & dosage / Q000737:chemistry; D013696:Temperature; D013997:Time Factors
D002395:Catecholamines; D004280:Dobutamine; D005947:Glucose; D004298:Dopamine; D009638:Norepinephrine; D004837:Epinephrine