title: Treatment of carcinoma in situ of the urethra with intraurethral instillations of bacillus Calmette-Guérin. Case report and review of literature.
abstract: We present the case of a 60-year-old man with carcinoma in situ of the urethra after previous successful radiotherapy of an invasive bladder tumor. Intraurethral instillations with bacillus Calmette-Guérin were given. In spite of initial success, recurrences developed after two courses of 12 intraurethral instillations, and radical surgery was performed. The use of bacillus Calmette-Guérin is reviewed with regard to the locations of superficial transitional cell carcinoma outside the bladder cavity.
authors.affiliation: Department of Urology, St. Radboud University Hospital, Nijmegen, The Netherlands.
authors.forename: J A
authors.initials: JA
authors.lastname: Witjes
authors.forename: F M
authors.initials: FM
authors.lastname: Debruyne
authors.forename: A P
authors.initials: AP
authors.lastname: van der Meijden
mesh_terms: D001500:BCG Vaccine / Q000008:administration & dosage / Q000627:therapeutic use*; D002278:Carcinoma in Situ / Q000628:therapy*; D002295:Carcinoma, Transitional Cell / Q000628:therapy*; D006801:Humans; D007322:Instillation, Drug; D008297:Male; D008875:Middle Aged; D014523:Urethral Neoplasms / Q000628:therapy*
chemical_list: D001500:BCG Vaccine