EDTA-induced pseudothrombocytopenia.
A 45-year-old man was admitted to the hospital because of unstable angina pectoris. During the wait for coronary artery bypass surgery, the platelet count gradually decreased from 154,000 to 20,000/mm3, without hemorrhagic manifestations. Medications were discontinued and surgery was postponed. Direct blood smear revealed a normal number of platelets, establishing the diagnosis of pseudothrombocytopenia. The mechanism of the development of pseudothrombocytopenia is not clear.
Mayan
H
H
Department of Medicine E, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Salomon
O
O
Pauzner
R
R
Farfel
Z
Z
D000789:Angina, Unstable / Q000097:blood; D002951:Citrates / Q000494:pharmacology; D019343:Citric Acid; D004492:Edetic Acid / Q000494:pharmacology*; D006493:Heparin / Q000494:pharmacology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010976:Platelet Count / Q000187:drug effects; D013921:Thrombocytopenia / Q000097:blood / Q000139:chemically induced*
D002951:Citrates; D019343:Citric Acid; D006493:Heparin; D004492:Edetic Acid