Use of a radioimmunoassay for 5-hydroxytryptamine (5-HT) in thrombocytosis.
A decrease in intra-platelet 5-hydroxytryptamine (5-HT) may be a possible marker for primary thrombocytosis and there are several different methods for the measurement of platelet 5-HT content (e.g. fluorimetry, high-performance liquid chromatography and radioimmunoassay). The present study has shown that, in laboratories with radioprotected areas, radioimmunoassay of 5-HT is a simple method which correlates well with a standard fluorimetric technique and yields satisfactory results in patients with thrombocytosis.
Randi
M L
ML
Institute of Medical Semeiotics, University Medical School of Padua, Italy.
Stocco
F
F
Tison
T
T
Fabris
F
F
Girolami
A
A
D000328:Adult; D001792:Blood Platelets / Q000737:chemistry*; D003594:Cytoplasmic Granules / Q000737:chemistry; D005260:Female; D005470:Fluorometry; D006801:Humans; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D012701:Serotonin / Q000097:blood* / Q000172:deficiency; D013922:Thrombocytosis / Q000097:blood*
D012701:Serotonin