title: No evidence of HIV-2 infection in subjects at risk for AIDS living in north-east Italy.
abstract: Sera samples from 1134 individuals (824 HIV-1 seropositive and 310 HIV-1 seronegative), collected from January 1988 to April 1990, were tested for HIV-2 antibodies by whole virus assays and synthetic peptide-based assays to determine the prevalence of HIV-2 infection in populations at risk for AIDS in North-East Italy (Veneto Region). Partial reactivities on HIV-2 Western Blot were a common finding in HIV-1 seropositive samples. None of the sera fulfilled the criteria for HIV-2 seropositivity, since only low-level reactivity was observed with an HIV-2 competitive ELISA test, and no reactivity occurred with an HIV-2 specific peptide. Therefore, there is no evidence of HIV-2 infection in this geographical area, to date.
authors.affiliation: Istituto di Oncologia, Padova, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Del Mistro
authors.forename: A
authors.initials: A
authors.lastname: De Rossi
authors.forename: E
authors.initials: E
authors.lastname: Francavilla
authors.forename: M T
authors.initials: MT
authors.lastname: Sartori
authors.forename: L
authors.initials: L
authors.lastname: Chieco-Bianchi
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology* / Q000276:immunology; D015483:HIV Antibodies / Q000032:analysis; D015658:HIV Infections / Q000453:epidemiology* / Q000276:immunology; D006679:HIV Seropositivity / Q000453:epidemiology / Q000276:immunology; D015497:HIV-1 / Q000276:immunology; D015498:HIV-2; D006801:Humans; D007558:Italy / Q000453:epidemiology; D015995:Prevalence; D012307:Risk Factors; D016036:Seroepidemiologic Studies
chemical_list: D015483:HIV Antibodies