title: Nucleotide profile in rat liver and intestine at portal vein obstruction and reflow.
abstract: Liver and intestinal nucleotides and energy charge levels were examined in rats at portal vein clamping for 1, 5 or 30 min and after reflow for 1 or 6 h following 30 min clamping. In both tissues, clamping resulted in a loss of ATP, energy charge, UTP, GTP, UDP-glucuronic acid and UDP-N-acetylhexosamine levels, which all, except ATP and total adenosine phosphates, essentially recovered at 1 h reflow. At 6 h reflow, liver UDP-glucuronic acid and liver glutathione decreased in both clamped and sham operated rats.
authors.affiliation: Department of Pathology, Lund University, University Hospital, Sweden.
authors.forename: B
authors.initials: B
authors.lastname: Jakobsson
authors.forename: I A
authors.initials: IA
authors.lastname: el Hag
authors.forename: U
authors.initials: U
authors.lastname: Stenram
mesh_terms: D000818:Animals; D003250:Constriction; D006160:Guanosine Triphosphate / Q000378:metabolism; D007413:Intestinal Mucosa / Q000378:metabolism*; D008099:Liver / Q000098:blood supply* / Q000378:metabolism; D008102:Liver Circulation; D008297:Male; D009711:Nucleotides / Q000378:metabolism*; D011169:Portal Vein / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D014535:Uridine Diphosphate Glucuronic Acid / Q000378:metabolism; D014544:Uridine Triphosphate / Q000378:metabolism
chemical_list: D009711:Nucleotides; D014535:Uridine Diphosphate Glucuronic Acid; D006160:Guanosine Triphosphate; D014544:Uridine Triphosphate