Histologic findings on the condylar process of the mandible in rats with reduced bone-mineral density.
We studied the histology of the condylar process in rats on a low calcium diet. Female rats aged 15 weeks were given a low Ca diet for 14 weeks, which reduced bone-mineral density, i.e., induced osteoporosis. Histologic observation revealed tylosis of the fibrous layer of the condyle, shrinkage of the cartilaginous layer, enlargement of the marrow cavity, reduction in the number of osteoblasts in the condylar neck, and cellular disarrangement and other morphologic changes of both the fibrocartilaginous and cartilaginous layers.
Shimahara
M
M
Department of Oral Surgery, Osaka Medical College, Japan.
Ono
K
K
Yoshida
Y
Y
Kono
K
K
D000818:Animals; D015519:Bone Density; D002118:Calcium / Q000172:deficiency*; D002356:Cartilage / Q000473:pathology; D005260:Female; D008335:Mandibular Condyle / Q000473:pathology*; D051381:Rats; D011919:Rats, Inbred Strains
D002118:Calcium