Sequence comparison between the haemagglutinin-neuraminidase genes of simian, canine and human isolates of simian virus 5.
The nucleotide sequence of the haemagglutinin-neuraminidase (HN) gene was determined for a simian (W3), human (LN) and two canine (CPI+/CPI-) isolates of simian virus 5 (SV5). A comparison of the predicted amino acid sequences revealed that the human and canine isolates varied from the simian isolate by 1.7% and 2.4% respectively. This lack of significant variation between the HN proteins of the four SV5 isolates suggests that insufficient differences have occurred between isolates to confine them to a specific host.
Baty
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DU
Department of Biochemistry and Microbiology, University of St Andrews, Fife, U.K.
Southern
J A
JA
Randall
R E
RE
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004279:DNA, Viral; D004285:Dogs; D005814:Genes, Viral; D015707:HN Protein / Q000235:genetics*; D000882:Haplorhini; D006801:Humans; D008969:Molecular Sequence Data; D010252:Paramyxoviridae / Q000235:genetics* / Q000302:isolation & purification; D012689:Sequence Homology, Nucleic Acid; D013045:Species Specificity
D004279:DNA, Viral; D015707:HN Protein