Rabbit syndrome, antidepressant use, and cerebral perfusion SPECT scan findings.
The rabbit syndrome is an extrapyramidal side effect associated with chronic neuroleptic therapy. Its occurrence in a patient being treated with imipramine is described, representing the first reported case of this syndrome in conjunction with antidepressants. Repeated cerebral perfusion SPECT scans revealed decreased basal ganglia perfusion while the movement disorder was present, and a return to normal perfusion when the rabbit syndrome resolved.
Fornazzari
L
L
Neuropsychopharmacology Research Unit, Clarke Institute of Psychiatry, Toronto, Ontario, Canada.
Ichise
M
M
Remington
G
G
Smith
I
I
D001480:Basal Ganglia Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000503:physiopathology; D002560:Cerebrovascular Circulation / Q000502:physiology; D003866:Depressive Disorder / Q000150:complications / Q000188:drug therapy; D005260:Female; D006801:Humans; D007099:Imipramine / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D013577:Syndrome; D015899:Tomography, Emission-Computed, Single-Photon
D007099:Imipramine