title: Specificity of functional changes during normal brain aging.
abstract: Although there is no question that age-related alterations in neural function occur in the central nervous system (CNS) of mammals, these changes tend to be somewhat circumscribed rather than completely global, even in pathological conditions. Examples of this kind of specificity of functional neural change are drawn from experiments on the electrophysiology of the senescent rat hippocampus.
authors.affiliation: Department of Psychology, University of Arizona, Tucson 85724.
authors.forename: C A
authors.initials: CA
authors.lastname: Barnes
authors.forename: T C
authors.initials: TC
authors.lastname: Foster
authors.forename: G
authors.initials: G
authors.lastname: Rao
authors.forename: B L
authors.initials: BL
authors.lastname: McNaughton
mesh_terms: D000375:Aging / Q000502:physiology*; D000818:Animals; D006624:Hippocampus / Q000502:physiology*; D007051:Ibotenic Acid / Q000031:analogs & derivatives / Q000494:pharmacology; D008564:Membrane Potentials / Q000502:physiology; D009473:Neuronal Plasticity / Q000502:physiology; D051381:Rats; D013569:Synapses / Q000502:physiology; D018350:alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
chemical_list: D007051:Ibotenic Acid; D018350:alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid