Regional sympathetic denervation in von Recklinghausen's disease with coronary spasm and myocarditis.
Two patients with von Recklinghausen's disease presented with coronary artery spasm, transient high concentrations of norepinephrine, catecholamine-induced myocarditis, and regional sympathetic denervation of the heart that was assessed by I-123 metaiodobenzylguanidine scintigram. It is postulated that regional sympathetic denervation of the heart may precipitate both coronary artery spasm and catecholamine-induced myocarditis in susceptible patients with von Recklinghausen's disease.
Nogami
A
A
Department of Internal Medicine, Toride Kyodo General Hospital, Ibaraki, Japan.
Hiroe
M
M
Marumo
F
F
D001342:Autonomic Nervous System Diseases / Q000150:complications / Q000378:metabolism / Q000503:physiopathology; D003329:Coronary Vasospasm / Q000209:etiology*; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging / Q000294:innervation*; D006801:Humans; D008875:Middle Aged; D009205:Myocarditis / Q000209:etiology*; D009410:Nerve Degeneration; D009456:Neurofibromatosis 1 / Q000150:complications* / Q000378:metabolism / Q000503:physiopathology; D009638:Norepinephrine / Q000097:blood / Q000652:urine; D013564:Sympathetic Nervous System / Q000503:physiopathology*; D015899:Tomography, Emission-Computed, Single-Photon; D016277:Ventricular Function, Left / Q000502:physiology
D009638:Norepinephrine