title: The value of parenchymal transit time index of Tc-99m DTPA diuretic renography in the evaluation of surgery in chronic bilharzial obstructive uropathy.
abstract: Selection of patients with chronic bilharzial uropathy (CBU) for surgery is a difficult problem due to the presence of grossly dilated urinary tracts without a significant obstruction in most of the cases. In this prospective study of 40 patients with CBU, the time-activity curve (TAC) patterns of the pre- and postoperative Tc-99m DTPA diuretic renography (RDR) studies were compared with the corresponding parenchymal transit time indices (PTTI). The aims were to find out which of these renographic parameters was more accurate in identifying obstruction and which was better in predicting the outcome of surgery. PTTI was more sensitive than TAC in identifying obstruction (96% and 92%, respectively) but it was less specific (78% and 98%). The detection accuracy of RDR for obstruction using TAC patterns was 96% compared to 84% using PTTI. Being independent of renal uptake function, PTTI could not predict the outcome of surgery as TAC could. In contrast to PTTI, TAC patterns could differentiate obstructed kidneys from severely nephropathic kidneys. However, PTTI was useful in identifying kidneys with residual nephropathy.
authors.affiliation: Department of Nuclear Medicine, Faculty of Medicine and Ministry of Public Health, Kuwait.
authors.forename: R H
authors.initials: RH
authors.lastname: Bahar
authors.forename: K
authors.initials: K
authors.lastname: Kouris
authors.forename: M
authors.initials: M
authors.lastname: Sabha
authors.forename: F M
authors.initials: FM
authors.lastname: Abu Zidan
authors.forename: M
authors.initials: M
authors.lastname: Awdeh
authors.forename: H M
authors.initials: HM
authors.lastname: Abdel-Dayem
mesh_terms: D000328:Adult; D002908:Chronic Disease; D005544:Forecasting / Q000379:methods; D005665:Furosemide; D006801:Humans; D008875:Middle Aged; D011184:Postoperative Period; D011446:Prospective Studies; D011866:Radioisotope Renography / Q000379:methods; D012553:Schistosomiasis haematobia / Q000000981:diagnostic imaging*; D012680:Sensitivity and Specificity; D016284:Technetium Tc 99m Pentetate; D013997:Time Factors; D016896:Treatment Outcome; D014517:Ureteral Obstruction / Q000000981:diagnostic imaging* / Q000469:parasitology / Q000601:surgery*
chemical_list: D005665:Furosemide; D016284:Technetium Tc 99m Pentetate