[Analysis of clinical factors and IgE-RAST of Dermatophagoides farinae and rice in atopic dermatitis by multiple factor analysis of quantification theory type II].
Twelve clinical factors and IgE-RAST of Dermatophagoides farinae (DF) and rice were analysed in three hundred patients with atopic dermatitis by multiple factor analysis of quantification theory Type II. Atopic dermatitis was simply defined here, as a patient who had typical eczematous eruption on the flexural portions of the body, such as the cubital fossa and/or the tibial fossa and/or the neck. The results were as follows: 1) Five clinical items such as onset age, age, history of asthma, sex, and history of allergic rhinitis were selected as significant variables to discriminate the objective variable of DF RAST, and influenced the discrimination in the order. The category of "less than 10 years-old" in the item of onset age, mostly influenced on the positive DF RAST, followed by the categories of "more than 20 years-old" in age, "presence of asthma", "presence of allergic rhinitis", and so on, in the order. 2) Five clinical items such as duration of the disease, eruption on the face, eruption on the trunks and/or extremities, sex, and age were selected as significant variables to discriminate the objective variable of rice RAST, and influenced the discrimination in the order. The category of "more than 5 years" in the item of duration of the disease, mostly influenced on the positive rice RAST, followed by the categories of refractory signs such as "lichenification on the face", "lichenification on the trunks and/or extremities", and so on, in the order. Based on the results by the multiple factor analysis, rice antigen was strongly suspected to have relation with refractory patients with atopic dermatitis.
Miyakawa
K
K
Department of Dermatology, National Sagamihara Hospital.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000276:immunology*; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D007223:Infant; D008297:Male; D008875:Middle Aged; D008925:Mites / Q000276:immunology*; D015999:Multivariate Analysis; D012275:Oryza; D011852:Radioallergosorbent Test
D007073:Immunoglobulin E