[Nuclear DNA assay in gynecologic malignant tumors and its clinical significance].
This paper analyzes the nuclear DNA content in 80 gynecologic tumors by microspectrophotometry and correlates the results of ovarian malignant tumors with the clinico-pathologic features of the tumor. The DNA content and the percentage of nuclei with over octaploid were significantly higher in gynecologic malignant tumors and ovarian germ cell tumors than in gynecologic benign tumors and ovarian epidermic tumors. The percentage of nuclei with over octaploid was significantly higher in advanced than in early tumors. It seems that DNA content assay may be helpful in the pathological diagnosis of gynecologic tumors.
Cheng
X
X
Xinqiao Hospital, Third Military Medical College, Chongqing, Sichuan.
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D000782:Aneuploidy; D004273:DNA, Neoplasm / Q000032:analysis*; D005260:Female; D006801:Humans; D015591:Microspectrophotometry; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D011123:Polyploidy; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology
D004273:DNA, Neoplasm