[Effects of polysaccharide from Thuja occidentale L. on stromal precursor cells of hematopoietic microenvironment in mice].
The effect of high molecular polysaccharide subfraction from Thuja occidentale L. (TPS) on stromal precursor cells of hematopoietic microenvironment under the "steady-state" conditions and after sublethal irradiation was investigated. The stromal precursor cells of different stages of differentiation were detected by the implantation of mouse bone marrow under the renal capsule of syngeneic intact recipients and chimeras. It was shown that TPS did not occur the toxic influence on the stromal precursor cells and provided the defense effect on them under the strong (6 Gy) radiation damages.
Gan
O I
OI
Medical Clinic, Hamburg, FRG.
Drize
N I
NI
Gola
S
S
Shrum
S
S
Net
R
R
D000818:Animals; D016026:Bone Marrow Transplantation; D006413:Hematopoietic System / Q000166:cytology* / Q000187:drug effects* / Q000528:radiation effects; D037102:Lectins; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology*; D011134:Polysaccharides / Q000494:pharmacology*
D037102:Lectins; D010936:Plant Extracts; D011134:Polysaccharides
Deĭstvie polisakharida iz Thuja occidentale L na stromal'nye kletki-predshestvenniki krovetvornogo mikrookruzheniia myshi.