title: [Human Parvovirus B19--really only fifth disease? Unusual disease course in children and adolescents].
abstract: The human parvovirus B19 agent causes infectious erythema (fifth disease). However, a wide range of other pathological manifestations may also be seen: atypical exanthema, ARD (also obstructive forms, e.g. bronchiolitis), acute gastroenteritis, chronic anemia or aplastic crises (in constitutional or malignant hematological diseases or immunological deficiency), arthralgia/arthritis (e.g. rheumatoid arthritis, jcA), diseases of the central nervous systems (e.g. febrile convulsions in young children), lymphadenopathies (e.g. lymphadenitis mesenterialis or pseudoappendicitis); prenatal infection can lead to fetal death (not malformations!). Infection occurring concomitantly with vaccination may suggest complications of the latter. To clarify the true etiological situation, modern laboratory investigations are then required. Vaccination against parvovirus B19 (initially indicated in the case of non-immune girls and women wanting children) is a desirable future development.
authors.affiliation: Klinik für Kindermedizin, Universität Greifswald.
authors.forename: S
authors.initials: S
authors.lastname: Wiersbitzky
authors.forename: R
authors.initials: R
authors.lastname: Bruns
mesh_terms: D000293:Adolescent; D000402:Airway Obstruction / Q000209:etiology; D002493:Central Nervous System Diseases / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D016731:Erythema Infectiosum / Q000150:complications* / Q000382:microbiology / Q000517:prevention & control; D005315:Fetal Diseases / Q000209:etiology; D005767:Gastrointestinal Diseases / Q000209:etiology; D006801:Humans; D016732:Parvovirus B19, Human / Q000276:immunology / Q000472:pathogenicity; D014765:Viral Vaccines
chemical_list: D014765:Viral Vaccines
vernacular_title: Humanes Parvovirus B19--wirklich nur "Ringelröteln"? Aussergewöhnliche Krankheitsverläufe bei Kindern und Jugendlichen.