title: Patterns of oxygenation after thoracotomy.
abstract: We have studied patterns of oxygen saturation (SpO2) before and after thoracotomy in 20 patients monitored nightly from the preoperative night to the fourth postoperative night. After operation, 10 patients received paravertebral bupivacaine (PVB) infusion and 10 received paravertebral saline (PVS) infusion. Papaveretum was given as required. Before operation the SpO2 profiles formed two groups: stable with SpO2 greater than 94% and stable with a median SpO2 less than 94% (hypoxaemia). During the first night after operation SpO2 profiles formed four groups: stable, not hypoxaemic (2/20); stable, hypoxaemic but improving (8/20); stable and constant hypoxaemia (5/20); unstable, hypoxaemic and deteriorating (5/20). Eleven patients remained hypoxaemic as late as the fourth night after operation. All patients who were hypoxaemic before operation were hypoxaemic after operation. Postoperative hypoxaemia was predicted in only 50% of cases. Papaveretum requirement was reduced in the PVB group, but regional analgesia did not affect the proportion of patients showing each SpO2 profile. Papaveretum caused a decrease in SpO2 in both analgesic groups.
authors.affiliation: Department of Anaesthetics, Bradford Royal Infirmary.
authors.forename: M D
authors.initials: MD
authors.lastname: Entwistle
authors.forename: P G
authors.initials: PG
authors.lastname: Roe
authors.forename: D J
authors.initials: DJ
authors.lastname: Sapsford
authors.forename: R G
authors.initials: RG
authors.lastname: Berrisford
authors.forename: J G
authors.initials: JG
authors.lastname: Jones
mesh_terms: D000328:Adult; D000368:Aged; D002045:Bupivacaine / Q000008:administration & dosage; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009892:Opium / Q000008:administration & dosage / Q000009:adverse effects; D010100:Oxygen / Q000097:blood*; D010102:Oxygen Inhalation Therapy; D010149:Postoperative Pain / Q000628:therapy; D011183:Postoperative Complications / Q000209:etiology*; D013908:Thoracotomy; D013997:Time Factors
chemical_list: D009892:Opium; D010100:Oxygen; D002045:Bupivacaine