Autosomal recessive inheritance of myopia in Hong Kong Chinese infants.
Hong Kong Chinese infants were refracted by retinoscopy at regular intervals between the age of approximately 10 and 40 weeks. Cyclopentolate 1% was used to obtain cycloplegia. The spherical equivalent of the refractive error was calculated for each child and analysis of variance carried out according to the refractive status of the parents. From approximately 20 weeks of age a significant difference was found between the mean spherical equivalent of the refractive error of infants of parents both of whom were myopic and that of infants of parents neither of whom was myopic. At 40 weeks of age a good fit with an autosomal recessive probability model was obtained.
Edwards
M
M
Department of Diagnostic Sciences, Hong Kong Polytechnic.
Lewis
W H
WH
D000328:Adult; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D002924:Ciliary Body / Q000187:drug effects; D003519:Cyclopentolate / Q000494:pharmacology; D005260:Female; D005808:Genes, Recessive; D006723:Hong Kong; D006801:Humans; D007223:Infant; D008297:Male; D008957:Models, Genetic; D009216:Myopia / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics*; D009887:Ophthalmoscopy; D010290:Parents
D003519:Cyclopentolate