title: Duration of cardiopulmonary bypass compared with changes in the plasma protease systems.
abstract: Forty patients undergoing elective coronary artery bypass grafting were investigated concerning association between duration of cardiopulmonary bypass (CPB) and changes in the plasma protease systems. Spontaneous enzyme activity, proenzymes and functional inhibition capacities in the fibrinolytic, plasma kallikrein-kinin and coagulation systems were measured before, during and after CPB and in the immediate postoperative period. No clear relationship was revealed between changes in the measured variables and the duration of CPB.
authors.affiliation: Department of Anaesthesiology, Rikshospitalet, Oslo, Norway.
authors.forename: U E
authors.initials: UE
authors.lastname: Kongsgaard
authors.forename: N
authors.initials: N
authors.lastname: Smith-Erichsen
authors.forename: O
authors.initials: O
authors.lastname: Geiran
authors.forename: L
authors.initials: L
authors.lastname: Bjørnskau
mesh_terms: D001777:Blood Coagulation / Q000502:physiology*; D002315:Cardiopulmonary Bypass; D010450:Endopeptidases / Q000097:blood; D005342:Fibrinolysis / Q000502:physiology*; D006801:Humans; D016234:Kallikrein-Kinin System / Q000502:physiology*; D008875:Middle Aged; D013997:Time Factors; D000979:alpha-2-Antiplasmin / Q000378:metabolism
chemical_list: D000979:alpha-2-Antiplasmin; D010450:Endopeptidases