Lipid modulators of epidermal proliferation and differentiation.
The importance of lipids within the skin as components of the permeability barrier has been appreciated for quite some time. However, the more recent work reviewed here suggests numerous alternative bioactive functions for lipid molecules within the skin and other tissues. The precise roles of lipids in epidermal proliferation and differentiation have only begun to be studied and are far from being defined.
Holleran
W M
WM
Department of Dermatology, University of California School of Medicine, San Francisco 94143.
D000818:Animals; D002454:Cell Differentiation; D002455:Cell Division; D000078404:Epidermal Cells; D004817:Epidermis / Q000201:enzymology / Q000378:metabolism; D050356:Lipid Metabolism; D008322:Mammals; D010740:Phospholipases / Q000378:metabolism; D010972:Platelet Activating Factor / Q000378:metabolism; D015398:Signal Transduction; D013107:Sphingolipids / Q000378:metabolism
D010972:Platelet Activating Factor; D013107:Sphingolipids; D010740:Phospholipases