title: HLA phenotype and haplotype frequencies in the Cantabria (middle north Spain) population.
abstract: The gene and haplotype frequencies of the HLA-A and -B locus antigens were determined in 502 unrelated individuals from Cantabria (middle North Spain). Our results were compared with those reported for other European and Spanish populations. The haplotypes with significant linkage disequilibrium were also analyzed in various Spanish population samples in order to establish possible relationships with geographic situation and historical events.
authors.affiliation: Departamento de Fisiología y Farmacología, Universidad de Cantabria, España.
authors.forename: R
authors.initials: R
authors.lastname: Calvet
authors.forename: J M
authors.initials: JM
authors.lastname: Pastor
authors.forename: R
authors.initials: R
authors.lastname: Fernández
authors.forename: A
authors.initials: A
authors.lastname: Zubizarreta
authors.forename: J L
authors.initials: JL
authors.lastname: Romero
mesh_terms: D005787:Gene Frequency / Q000235:genetics*; D006680:HLA Antigens / Q000235:genetics*; D006239:Haplotypes / Q000235:genetics*; D006801:Humans; D015810:Linkage Disequilibrium / Q000235:genetics; D010641:Phenotype; D013030:Spain / Q000208:ethnology
chemical_list: D006680:HLA Antigens