title: [Effects of the removal of the epiphysis on the hypnogenic action of hexanal in rats].
abstract: After pinealectomy a potentiation of the hypnogenic effect of hexobarbital sodium was observed in rats, which was particularly expressed during night hours. Melatonin (0.1 mg/kg, i.p.) attenuated but not fully eliminate this effect. As suggested pineal compounds have an antihypnogenic activity which can be of a pharmacokinetic and pharmacodynamic origin.
authors.forename: E B
authors.initials: EB
authors.lastname: Arushanian
authors.forename: P
authors.initials: P
authors.lastname: Votvev Orkhiĭ
mesh_terms: D000447:Aldehydes / Q000494:pharmacology*; D000818:Animals; D002940:Circadian Rhythm; D006591:Hexobarbital / Q000494:pharmacology*; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D010870:Pineal Gland / Q000502:physiology* / Q000601:surgery; D012621:Seasons
chemical_list: D000447:Aldehydes; C010463:n-hexanal; D006591:Hexobarbital; D008550:Melatonin
vernacular_title: Vliianie udaleniia épifiza na gipnogennoe deĭstvie geksenala u krys.