[Correlation of local immune system indices of patients with tuberculous and serous meningitis].
The method of discrete-dynamic analysis was used for studying the immunity system state in 60 patients with tuberculous meningitis (TM) of various degree of severity and in 35 patients with serous meningitis of nontuberculous etiology (SMNE). A significant difference was established of the correlation between parameters in the combinations comprising lymphocytes immune to Mycobacterium tuberculosis which enables TM and SMNE differentiation. TM was characterized by a sharp increase in the number of correlations (intensity) in the parameters as compared with SMNE. Intensity significantly declines in the fatal outcome of TM as compared with this parameter in the survived patients. In SMNE local immunity state normalizes (intensity decline) in 1.5-2 months, in TM of moderate severity in 3 months and in a serious course (during the follow-up) intensity does not decline.
Gogebashvili
N V
NV
Gvetadze
I G
IG
Poniakina
I D
ID
D000293:Adolescent; D000917:Antibody Formation; D002648:Child; D006801:Humans; D007111:Immunity, Cellular; D008581:Meningitis / Q000276:immunology*; D012189:Retrospective Studies; D014390:Tuberculosis, Meningeal / Q000276:immunology*
Vzaimosviazi pokazateleĭ mestnoĭ immunnoĭ sistemy bol'nykh tuberkulezom i seroznym meningitom.