Reduced concentration of secretory IgA indicates changes of local immunity in children with adenoid hyperplasia and secretory otitis media.
Children with adenoid hyperplasia and secretory otitis media show significantly lower immunoglobulin A (sIgA) concentrations in their saliva compared to matched controls. Salivary albumin and cortisol levels do not differ in both groups. Changes in local immunity, dilution or stress as possible factors for the reduction of sIgA concentrations are discussed.
Hess
M
M
HNO-Klinik, Universität Düsseldorf, BRD.
Kugler
J
J
Haake
D
D
Lamprecht
J
J
D000234:Adenoids / Q000276:immunology*; D000418:Albumins / Q000032:analysis; D016022:Case-Control Studies; D002648:Child; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis; D006965:Hyperplasia; D007071:Immunoglobulin A, Secretory / Q000032:analysis*; D008297:Male; D015508:Nasal Obstruction / Q000276:immunology; D010034:Otitis Media with Effusion / Q000276:immunology*; D012463:Saliva / Q000737:chemistry / Q000276:immunology*; D012471:Salivary Proteins and Peptides / Q000032:analysis
D000418:Albumins; D007071:Immunoglobulin A, Secretory; D012471:Salivary Proteins and Peptides; D006854:Hydrocortisone