[Neurophysiological mechanisms of the antihypertensive effect of clopheline in pain].
In experiments on conscious and unanesthetized cats it was shown that clopheline in analgesic doses do not change the pain baroreflex blood pressure regulation and mild brain antinociceptive sympathoactivating influences. The clopheline antihypertensive effect was due to nonopiate direct sympathoinhibitory effect realized by suprasegmental level of vasomotor regulation.
Ignatov
Iu D
IuD
Bogdanov
E G
EG
Zaĭtsev
A A
AA
Khar'kovskiĭ
A O
AO
D000818:Animals; D000959:Antihypertensive Agents; D002415:Cats; D003000:Clonidine / Q000008:administration & dosage / Q000494:pharmacology*; D006439:Hemodynamics / Q000187:drug effects; D010146:Pain / Q000188:drug therapy*; D010147:Pain Measurement; D014666:Vasomotor System / Q000187:drug effects
D000959:Antihypertensive Agents; D003000:Clonidine
Neĭrofiziologicheskie mekhanizmy antigipertenzivnogo éffekta klofelina pri boli.