title: Antimicrobial and antiviral activity of xylosyl-methylthio-adenosine, a naturally occurring analogue of methylthio-adenosine from Doris verrucosa.
abstract: Xylosyl-methylthio-adenosine, a naturally occurring analogue of 5'-deoxy-5'-methylthio-adenosine, has been postulated to play a protective role during egg development in the mollusc Doris verrucosa. However, in vitro tests showed that this analogue is devoid of activity against fungi, bacteria and viruses.
authors.affiliation: Dipartimento di Biologia Sperimentale, Universitá di Cagliari, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Pani
authors.forename: M E
authors.initials: ME
authors.lastname: Marongiu
authors.forename: P
authors.initials: P
authors.lastname: Obino
authors.forename: M
authors.initials: M
authors.lastname: Gavagnin
authors.forename: P
authors.initials: P
authors.lastname: La Colla
mesh_terms: D000241:Adenosine / Q000031:analogs & derivatives* / Q000494:pharmacology; D000818:Animals; D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D000998:Antiviral Agents / Q000494:pharmacology; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D003839:Deoxyadenosines / Q000494:pharmacology*; D008974:Mollusca / Q000737:chemistry*; D013872:Thionucleosides / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D000998:Antiviral Agents; D003839:Deoxyadenosines; D013872:Thionucleosides; C014251:9-xylosyladenine; C056833:9-(5'-deoxy-5'-(methylthio)-xylofuranosyl)adenine; C008500:5'-methylthioadenosine; D000241:Adenosine