title: The metabolism of tamoxifen by human liver microsomes is not mediated by cytochrome P450IID6.
authors.affiliation: University Department of Medicine and Pharmacology, Royal Hallamshire Hospital, Sheffield, U.K.
authors.forename: E A
authors.initials: EA
authors.lastname: Blankson
authors.forename: S W
authors.initials: SW
authors.lastname: Ellis
authors.forename: M S
authors.initials: MS
authors.lastname: Lennard
authors.forename: G T
authors.initials: GT
authors.lastname: Tucker
authors.forename: K
authors.initials: K
authors.lastname: Rogers
mesh_terms: D019389:Cytochrome P-450 CYP2D6; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D008862:Microsomes, Liver / Q000201:enzymology* / Q000378:metabolism; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism*; D011802:Quinidine / Q000494:pharmacology; D013379:Substrate Specificity; D013629:Tamoxifen / Q000031:analogs & derivatives / Q000737:chemistry / Q000378:metabolism* / Q000493:pharmacokinetics
chemical_list: D065607:Cytochrome P-450 Enzyme Inhibitors; D013629:Tamoxifen; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D019389:Cytochrome P-450 CYP2D6; D011802:Quinidine; C028787:N-desmethyltamoxifen