title: [Physiopathology, exploration and treatment of calcium lithiasis].
abstract: The main risk factors for calcium urolithiasis that are clinically detectable are low diuresis, hypercalciuria, hyperruricuria, alkaline urinary pH, hyperoxaluria, hypomagnesuria, hypocitraturia. They should be evaluated, all the more precisely that the disease is active, under both the urological and metabolic points of view, using 24 hour urine collection made at home on a free diet with a dietary record. In the majority of the cases the calcic urolithiasis is idiopathic, i.e. not related to a cause of secondary hypercalciuria like primary hyperparathyroidism, or to a hyperroxaluria either primary or of digestive or toxic origin. Its treatment if mainly dietary with high fluid intake (diuresis greater than 2 1/24 h), normoclacic diet (800-1000h mh/24 h) with meat but not dairy product restriction, oxalate salts, carbohydrate and alcohol restriction. These dietary recommendations should be controlled by measuring the above cited parameters in the 24 hour urine samples and by measuring urea excretion which should not exceed 0.33 g/kg of body weight. When diet fails, drugs may be added mainly allopurinol, thiazides and potassium citrate.
authors.affiliation: Service de néphrologie, centre hospitalier, Boulogne-sur-Mer.
authors.forename: P
authors.initials: P
authors.lastname: Bataille
authors.forename: J M
authors.initials: JM
authors.lastname: Achard
authors.forename: A
authors.initials: A
authors.lastname: Fournier
mesh_terms: D002118:Calcium / Q000737:chemistry*; D006801:Humans; D007669:Kidney Calculi / Q000737:chemistry* / Q000503:physiopathology / Q000517:prevention & control / Q000628:therapy
chemical_list: D002118:Calcium
vernacular_title: Physiopathologie, exploration et traitement de la lithiase calcique.