title: Oropharyngeal and esophageal function in scleroderma.
abstract: Fifty-one patients with systemic sclerosis (scleroderma) underwent videofluoroscopy during barium swallow to evaluate the incidence of oropharyngeal deglutition abnormalities and to correlate the radiologic patterns of esophageal motility abnormalities with patients' clinical features. Thirteen patients (26%) showed swallowing dysfunction, (e.g., oral leakage, retention, penetration, mild or moderate aspiration, and upper esophageal sphincter incoordination). These dysfunctions were more severe in patients with prominent esophageal dysmotility. Normal esophageal motility was not associated with swallowing alterations. Patients with an oropharyngeal disorder had a higher incidence of pulmonary disease. The clinical picture of the above-mentioned 13 patients was more severe, based on the duration of Raynaud's phenomenon and duration of skin sclerosis. Patients with primary Raynaud's phenomenon had no oral or esophageal abnormalities. The esophageal phase of swallowing was abnormal in 80% of the patients with scleroderma. Esophageal dysfunction, therefore, seems to be frequent in the early stages of the disease. However, patients with advanced or extensive disease may have normal esophageal function.
authors.affiliation: Servizio di Radiologia, Ospedale Regionale Umberto 1st, Ancona, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Montesi
authors.forename: A
authors.initials: A
authors.lastname: Pesaresi
authors.forename: M L
authors.initials: ML
authors.lastname: Cavalli
authors.forename: G
authors.initials: G
authors.lastname: Ripa
authors.forename: M
authors.initials: M
authors.lastname: Candela
authors.forename: A
authors.initials: A
authors.lastname: Gabrielli
mesh_terms: D000328:Adult; D000368:Aged; D003680:Deglutition Disorders / Q000503:physiopathology; D015154:Esophageal Motility Disorders / Q000503:physiopathology; D004947:Esophagus / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009960:Oropharynx / Q000503:physiopathology*; D010528:Peristalsis / Q000502:physiology; D012595:Scleroderma, Systemic / Q000503:physiopathology*