[Malignant hyperthermia today].
Besides offering a concise recapitulation of known facts, experiences and related viewpoints concerning malignant hyperthermia (MH), the present article offers a review of the most relevant new aspects in this field. Special emphasis is on genetics and pathogenesis of MH. The contents of the review are as follows: History; Definition of MH; Epidemiological aspects; Inheritance; Molecular genetics; Pathogenesis; Triggering agents; Awake Triggering; Sympathetic nervous system; Serotoninergic system; Involvement of other organs and cell systems; Clinical symptoms and diagnosis; MH and myopathies; Associated disorders; Treatment; Prophylaxis; Identification of susceptibility; MH testing centres in the FRG; Hot-line for MH emergencies
Roewer
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Abteilung für Anästhesiologie, Universitäts-Krankenhaus Eppendorf, Hamburg.
D005060:Europe; D049673:History, 20th Century; D006801:Humans; D008305:Malignant Hyperthermia / Q000209:etiology / Q000235:genetics / Q000266:history; D014481:United States
Maligne Hyperthermie heute.