[Comparative study on growth kinetics of organisms causing purulent infections in the presence of ofloxacin and ciprofloxacin].
The comparative study of the antimicrobial effect of ofloxacin and ciprofloxacin on the in vitro kinetic models of the pathogen growth showed that ciprofloxacin was more active against Staphylococcus aureus and Pseudomonas aeruginosa. The post-antibiotic effect depended of the drug concentration and period of the pathogen content with ofloxacin and ciprofloxacin. With respect to the both pathogens, the post-antibiotic effect of ciprofloxacin was more pronounced.
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D002939:Ciprofloxacin / Q000494:pharmacology*; D007700:Kinetics; D008826:Microbial Sensitivity Tests; D015242:Ofloxacin / Q000494:pharmacology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000254:growth & development; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000254:growth & development
D002939:Ciprofloxacin; D015242:Ofloxacin
Sravnitel'noe izuchenie kinetiki rosta mikrobov--vozbuditeleĭ gnoĭnoĭ infektsii v prisutstvii ofloksatsina i tsiprofloksatsina.