title: Delineating the pharmacophoric elements of huperzine A: importance of the unsaturated three-carbon bridge to its AChE inhibitory activity.
authors.affiliation: Neurochemistry Research and Neuropharmacology Research, Mayo Clinic Jacksonville, Florida 32224.
authors.forename: A P
authors.initials: AP
authors.lastname: Kozikowski
authors.forename: C P
authors.initials: CP
authors.lastname: Miller
authors.forename: F
authors.initials: F
authors.lastname: Yamada
authors.forename: Y P
authors.initials: YP
authors.lastname: Pang
authors.forename: J H
authors.initials: JH
authors.lastname: Miller
authors.forename: M
authors.initials: M
authors.lastname: McKinney
authors.forename: R G
authors.initials: RG
authors.lastname: Ball
mesh_terms: D000470:Alkaloids; D000818:Animals; D001921:Brain / Q000201:enzymology; D002800:Cholinesterase Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D066298:In Vitro Techniques; D008958:Models, Molecular; D008968:Molecular Conformation; D051381:Rats; D012717:Sesquiterpenes / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D000470:Alkaloids; D002800:Cholinesterase Inhibitors; D012717:Sesquiterpenes; C050426:huperzine A