title: [Diagnostic value of the deletion of the delta F508 gene in cystic fibrosis].
abstract: We have studied 70 carrier cystic fibrosis (CF) families with delta F508 mutation using the polymerase chain reaction (P.C.R.). We found that frequency of the mutation in CF chromosomes was 53%. 39% of carrier cystic fibrosis families were informative for the mutation.
authors.affiliation: Departamento de Genética, Fundación Jiménez Díaz, Madrid.
authors.forename: E
authors.initials: E
authors.lastname: Fernández García
authors.forename: V
authors.initials: V
authors.lastname: Nunes Martínez
authors.forename: M A
authors.initials: MA
authors.lastname: Ibáñez Olias
authors.forename: J
authors.initials: J
authors.lastname: Benítez Ortíz
mesh_terms: D002648:Child; D002872:Chromosome Deletion; D003550:Cystic Fibrosis / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics*; D005787:Gene Frequency; D006801:Humans; D009154:Mutation; D010375:Pedigree; D013030:Spain / Q000453:epidemiology
vernacular_title: Valor diagnóstico de la deleción delta F508 del gen de la fibrosis quística (FQ).