Metabolism and action of 2',2'-difluorodeoxycytidine: self-potentiation of cytotoxicity.
Gandhi
V
V
Department of Medical Oncology, University of Texas M. D. Anderson Cancer Center, Houston 77030.
Huang
P
P
Xu
Y Z
YZ
Heinemann
V
V
Plunkett
W
W
D001085:Arabinofuranosylcytosine Triphosphate / Q000494:pharmacology; D001483:Base Sequence; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D003844:DCMP Deaminase / Q000378:metabolism; D004257:DNA Polymerase II / Q000378:metabolism*; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D003845:Deoxycytosine Nucleotides / Q000494:pharmacology; D003854:Deoxyribonucleotides / Q000378:metabolism*; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive; D008969:Molecular Sequence Data; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma; D014410:Tumor Stem Cell Assay; D000093542:Gemcitabine
D003845:Deoxycytosine Nucleotides; D003854:Deoxyribonucleotides; D009838:Oligodeoxyribonucleotides; D003841:Deoxycytidine; D001085:Arabinofuranosylcytosine Triphosphate; C024107:2'-deoxycytidine 5'-triphosphate; D004257:DNA Polymerase II; D003844:DCMP Deaminase; D000093542:Gemcitabine