title: [Significance of blood Ca(++) determination for assessment of the current status of calcium homeostasis].
abstract: Out of the blood calcium fractions know only the ionized calcium is biologically active. From the height of the total calcium level despite significant dependence no secure conclusion to the Ca++ concentration can be drawn. The level of the total calcium spreads further than that one of the ionized calcium. The up to now used mathematical approaches for the estimation of the blood Ca++ concentration also proved unsuitable; none of them provides a really better statement than the total calcium level. Thus even they represent no acceptable alternative to the Ca++ determination by means of ion-selective electrodes. The investigation by means of ion-selective electrodes. The investigation of various paraclinical sizes (total calcium, total protein, albumin, creatinine, alkaline phosphatase) in a group of patients and a control group in quality and quantity resulted in a different influence on the Ca++ level by the influential factors tested. Only by measurement of the ionized calcium the real actual condition of the calcium homoeostasis can be reflected. Therefore it is no more justified to draw diagnostically and therapeutically relevant consequences from the exclusive determination of the total calcium level.
authors.affiliation: Klinik und Poliklinik für Innere Medizin, Universität Rostock.
authors.forename: H
authors.initials: H
authors.lastname: Böhringer
authors.forename: H
authors.initials: H
authors.lastname: Börner
authors.forename: P
authors.initials: P
authors.lastname: Jeroschewski
authors.forename: C
authors.initials: C
authors.lastname: Teickner
mesh_terms: D000328:Adult; D000469:Alkaline Phosphatase / Q000097:blood; D001798:Blood Proteins / Q000378:metabolism*; D002118:Calcium / Q000097:blood*; D003404:Creatinine / Q000097:blood; D005260:Female; D006706:Homeostasis / Q000502:physiology*; D006801:Humans; D008223:Lymphoma / Q000097:blood; D008297:Male; D008875:Middle Aged; D008962:Models, Theoretical; D009196:Myeloproliferative Disorders / Q000097:blood; D009369:Neoplasms / Q000097:blood; D010265:Paraproteinemias / Q000097:blood; D012016:Reference Values; D012709:Serum Albumin / Q000378:metabolism
chemical_list: D001798:Blood Proteins; D012709:Serum Albumin; D003404:Creatinine; D000469:Alkaline Phosphatase; D002118:Calcium
vernacular_title: Die Bedeutung der Blut-Ca(++)-Bestimmung für die Einschätzung des aktuellen Zustandes der Calciumhomöostase.