The mild hypertension enigma.
This study examines the problem of the correlation between mild arterial hypertension and cardiovascular damage. The authors examine the results of the most important trials carried out and, on the basis of their evaluations, suggest the need to review the current clinical policy of considering mild arterial hypertension as an important risk factor directly related to cardiovascular disease. Since the therapeutic trials carried out on mild hypertension did not substantially reduce the total and cardiac mortality rate, it seems to be probable that arterial hypertension is a progression acceleration marker of atheromatous disease. According to this theory, a therapy which aims merely at returning the pressure values to normal limits will probably not change the natural course of the atheromatous process.
Antonicelli
R
R
Department of Cardiovascular Pathology and Arterial Hypertension, INRCA (Italian National Research Centre on Aging,) Ancona, Italy.
Amadio
L
L
Paciaroni
E
E
D002318:Cardiovascular Diseases / Q000150:complications* / Q000401:mortality / Q000517:prevention & control; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000401:mortality / Q000628:therapy; D008954:Models, Biological