History of clinical trials.
Advances in medical treatments have occurred because of the application of new knowledge gained from clinical experiments conducted over the last 250 years. New sources of compounds with anti-tumor activity in human cancer are constantly under investigation. The development of a new drug is a complex process: screening, formulation, production, toxicology studies, FDA approval, and evaluation in phase I, II, and III clinical trials.
Jenkins
J
J
Cancer Nursing Service, National Institutes of Health, Bethesda, MD 20892.
Hubbard
S
S
D000970:Antineoplastic Agents / Q000592:standards / Q000627:therapeutic use; D002985:Clinical Protocols / Q000592:standards; D002986:Clinical Trials as Topic / Q000266:history*; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D012106:Research / Q000266:history* / Q000458:organization & administration / Q000592:standards; D012107:Research Design / Q000592:standards; D014481:United States
D000970:Antineoplastic Agents