title: [Thrombocytapheresis with the (Baxter) A 201 cell separator--initial data of biocompatibility].
abstract: The cell separator A 201 was a new platelet pheresis prototype designed to carry out a discontinuous apheresis while platelet-rich plasma (PRP) is sampled continuously. After donation, a platelet concentrate (PC) and a fresh frozen plasma was collected from the PRP by the plasma cell-C device. The PC contained 2.6 +/- 0.7 x 10(11) platelets with a leucocyte contamination of 3.9 +/- 3.9 x 10(8) and an erythrocyte contamination of 3.0 +/- 3.0 x 10(8). The fresh frozen plasma was nearly cell-free. Prior, during and after apheresis we analysed hemolysis and coagulation parameters. There was no evidence for hemolysis. The analysis of the coagulation factors and of the Thrombin-Antithrombin III-complex, however, gave a hint of an activation of coagulation.
authors.affiliation: Blutspende- und Transfusionsdienst, Universitätsklinikums Essen.
authors.forename: R
authors.initials: R
authors.lastname: Moog
authors.forename: W
authors.initials: W
authors.lastname: Luboldt
authors.forename: A
authors.initials: A
authors.lastname: Krützfeldt
authors.forename: D
authors.initials: D
authors.lastname: Paar
authors.forename: M
authors.initials: M
authors.lastname: Holtmann
authors.forename: A K
authors.initials: AK
authors.lastname: Mengelkamp
mesh_terms: D001672:Biocompatible Materials; D001780:Blood Coagulation Tests; D004868:Equipment Failure; D006461:Hemolysis / Q000502:physiology; D006801:Humans; D007958:Leukocyte Count; D008422:Materials Testing; D010976:Platelet Count; D010983:Plateletpheresis / Q000295:instrumentation*
chemical_list: D001672:Biocompatible Materials
vernacular_title: Thrombozytapherese mit dem Zellseparator A 201 (Baxter)--erste Daten zur Biokompatibilität.