Familial congenital brachial palsy.
Eight relatives in a Sicilian family, including a sibship of 5, were affected with severe unilateral congenital brachial palsy (CBP) in a pattern suggesting autosomal dominant inheritance with reduced penetrance (6 cases affected on the right, 2 on the left). X-linked inheritance with expression in heterozygous females cannot be excluded.
Mollica
F
F
Clinica Pediatrica, University of Catania, Italy.
Li Volti
S
S
Grasso
A
A
De Simone
D
D
D001132:Arm / Q000002:abnormalities*; D001917:Brachial Plexus / Q000503:physiopathology*; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000235:genetics; D005260:Female; D005799:Genes, Dominant / Q000235:genetics*; D006801:Humans; D008297:Male; D010243:Paralysis / Q000150:complications / Q000151:congenital / Q000235:genetics*; D010375:Pedigree