[Changes in the cerebral blood flow in neurosurgical patients during general anesthesia using antihypoxic agents].
Cerebral blood flow (CBF) and central hemodynamics (CH) have been studied during anesthesia and after surgery in patients with tumours located in brain hemispheres. CBF and CH were determined by radiography. GOBA, diazepam and sodium thiopental were used for anesthesia. It has been shown that GOBA fails to normalize CBF both during and after surgery, diazepam normalizes blood flow in both brain hemispheres. Sodium thiopental leads to further CBF depression up to critical level in the affected hemisphere with parallel blood flow ingress in the intact brain hemisphere. It is concluded that the use of diazepam is advisable for anesthesia during surgery for tumours located in brain hemispheres.
Vasil'kov
V G
VG
Kosov
B L
BL
Marinchev
V N
VN
D000328:Adult; D000771:Anesthesia, Intravenous; D002560:Cerebrovascular Circulation / Q000187:drug effects / Q000502:physiology*; D003975:Diazepam; D006801:Humans; D002534:Hypoxia, Brain / Q000517:prevention & control*; D012978:Sodium Oxybate; D015173:Supratentorial Neoplasms / Q000503:physiopathology / Q000601:surgery*; D013874:Thiopental
D012978:Sodium Oxybate; D013874:Thiopental; D003975:Diazepam
Izmeneniia mozgovogo krovotoka u neĭrokhirurgicheskikh bol'nykh vo vremia obshcheĭ anestezii s ispol'zovaniem antigipoksantov.