title: Teratogenicity studies of a new potent tetanus vaccine in rabbit (Oryctolagus cuniculus).
abstract: Glaxo Laboratories, Bombay, have prepared a potent tetanus vaccine of 250 Lf as a substitute of the previous 5 Lf tetanus vaccine. The safety evaluation of the vaccine has been reported, but the teratogenic potential was not studied. In the experiment reported herein we have studied the teratogenic action of the vaccine in the progeny of rabbits. No congenital anomalies were observed.
authors.affiliation: Division of Toxicology, Central Drug Research Institute, Lucknow, India.
authors.forename: N
authors.initials: N
authors.lastname: Sethi
authors.forename: R K
authors.initials: RK
authors.lastname: Srivastava
authors.forename: R K
authors.initials: RK
authors.lastname: Singh
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D005314:Embryonic and Fetal Development / Q000187:drug effects; D005260:Female; D011247:Pregnancy; D011817:Rabbits; D013723:Teratogens / Q000633:toxicity*; D013745:Tetanus Toxoid / Q000633:toxicity*; D015430:Weight Gain / Q000187:drug effects
chemical_list: D013723:Teratogens; D013745:Tetanus Toxoid