title: [75 years of Cignolin].
abstract: Eugen Galewsky (1864-1935), dermatologist in Dresden, introduced 1,8-dihydroxyanthrone (Cignolin, Dithranol) for therapy of psoriasis. He intended to substitute Chrysarobin, a synthetic product, which causes strong discolouring and irritation of skin. In 1916 the firm Farbenfabrik Bayer, Leverkusen, obtained a patent for synthesis of 1.8-dihydroxyanthrone by an inexpensive method. There is a reason to believe that the brother of Eugen Galewsky, the chemist Paul Galewsky, was a co-worker to the Farbenfabrik Bayer and that he recommended his brother Eugen testing Cignolin. Even now Cignolin is still used in the treatment of psoriasis.
authors.affiliation: Hautabteilung, Medizinischen Akademie Carl Gustav Carus, Dresden.
authors.forename: A
authors.initials: A
authors.lastname: Scholz
authors.forename: H
authors.initials: H
authors.lastname: Kadner
mesh_terms: D000875:Anthralin / Q000266:history*; D005858:Germany; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D011565:Psoriasis / Q000188:drug therapy / Q000266:history
chemical_list: D000875:Anthralin
vernacular_title: 75 Jahre Cignolin.