Constituents and biological activity of Bidens pilosa L. grown in Egypt.
Column chromotography and preparative TLC of the light petroleum-diethyl ether extract from Bidens pilosa L. afforded tridecapentyn-1-ene, trideca-2,12-diene-4,6,8,10-tetrayne-1-ol, trideca-3,11-diene-5,7,9-triyne-1,2-diol and trideca-5-ene-7,9,11-triyne-3-ol. The compounds were identified on the bases of UV, 1H-NMR spectra and comparison with reported data. The chloroform extract was chromatographed to yield B-amyrin, phytosterin-B, esculetin and B-sitosterol glucoside. The petroleum ether extract afforded long chain ester, saturated hydrocarbon, long chain alcohol, B-amyrin, phytosterin-B, lupeol and lupeol acetate. GLC analysis of the fatty acids indicated the presence of 5 acids. The antimicrobial test was carried out to indicate an evident activity. The antidiabetic activity showed non significant decrease of blood glucose.
Sarg
T M
TM
Department of Pharmacognosy, Faculty of Pharmacy, University of Zagazig, Egypt.
Ateya
A M
AM
Farrag
N M
NM
Abbas
F A
FA
D000818:Animals; D002845:Chromatography; D004534:Egypt; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats
D010936:Plant Extracts