title: Acute lymphoblastic leukemia in the Department of Child Health, School of Medicine, University of North Sumatera/Dr. Pirngadi Hospital Medan (1980-1988).
abstract: A retrospective study on acute lymphoblastic leukemia (ALL) was conducted to assess the pattern of childhood ALL at the Subdivision of Pediatric of Hematology, School of Medicine, University of North Sumatera/Dr. Pirngadi Hospital, Medan, in a period of 8 years (1980-1988). There were 120 cases, consisting of 63 (52.5%) males and 57 (47.5%) females. By the FAB classification (Bennett, 1976) (77.5%) were found as FAB L 1, 25 (20.8%) as FAB L 2, and 2 (1.7%) as FAB L 3. The youngest was 4 months old. The majority of signs and symptoms appeared in the forms of pallor 102 (85%), fever 84 (70%), hemorrhage 52 (43.3%), hepatomegaly 64 (53.3%), splenomegaly 54 (45%) and lymphadenopathy 18 (15%). On first admission, 76 (63.33%) cases were with a leukocyte count of less than 20,000/microliters, and 72 (60%) with Hb content of less than 5 g/dl. Twenty one cases died in the first year. The received cytostatic protocol; 11 (52.38%) were treated regularly and first remission were found in 8 (72.73%) cases. The average of admissions per year for the age group of 2-8 years was higher than the age groups of 0-2 years and 8-16 years (p less than 0.05).
authors.affiliation: Department of Child Health, School of Medicine, University of North Sumatera/Dr. Pirngadi Hospital, Medan.
authors.forename: Z
authors.initials: Z
authors.lastname: Arifin
authors.forename: F
authors.initials: F
authors.lastname: Nasution
authors.forename: A
authors.initials: A
authors.lastname: Sutjipto
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006454:Hemoglobins / Q000032:analysis / Q000145:classification; D006785:Hospitals, University; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000097:blood; D007214:Indonesia / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D007958:Leukocyte Count; D008297:Male; D010343:Patient Admission / Q000706:statistics & numerical data / Q000639:trends; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000097:blood / Q000188:drug therapy / Q000453:epidemiology*; D012189:Retrospective Studies
chemical_list: D006454:Hemoglobins; D007140:Immunoglobulin Fab Fragments