[Computer selection of thrombocyte donors based on the HLA system].
Thrombocyte concentrates are vitally important in thrombocytopenic types of haemorrhage. If repeated transfusions are necessary, they are associated with immunological reactions, which cause side-effects in the recipient and the transfusion is ineffective. Donors should be selected according to the HLA system. The authors prepared a programme in the Redap language for selection of donors according to HLA antigens (loci A and B) which respects cross reactions and split antigens. The donor is selected by the grade of agreement with the recipient. The authors differentiate between nine possibilities from complete agreement to complete disagreement between donor and recipient. The initial experience revealed that the programme is feasible for the user and is sufficiently quick.
Bláha
M
M
Vojenská lékarská akademie, Hradec Králové.
Stránský
P
P
Pecka
M
M
Malý
J
J
D001782:Blood Donors; D006680:HLA Antigens / Q000032:analysis*; D006648:Histocompatibility; D006801:Humans; D010983:Plateletpheresis; D012042:Registries; D012984:Software
D006680:HLA Antigens
Výbĕr dárců trombocytů podle HLA systému na pocítaci.