A double-blind clinical trial to compare the efficacy of an active based cream F14001 against a placebo non-active based cream for the treatment of pressure ulcers in a population of elderly subjects.
A double-blind clinical trial was conducted to compare the efficacy of an active based cream against a placebo non-active based cream in the healing of superficial pressure ulcers in a population of geriatric hospital patients and residents in community nursing homes. The active group showed a small significant beneficial effect at week four. The overall results of the trial also demonstrated a significant improvement in ulcer size over the duration of the trial period in both active and placebo groups.
LeVasseur
S A
SA
National Research Institute of Gerontology and Geriatric Medicine, Mount Royal Hospital, Parkville, Victoria, Australia.
Helme
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RD
D000287:Administration, Topical; D000368:Aged; D000369:Aged, 80 and over; D002592:Cetomacrogol / Q000008:administration & dosage / Q000627:therapeutic use*; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D001467:Hordeum; D006801:Humans; D008297:Male; D009730:Nursing Assessment; D010919:Placebos; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D003668:Pressure Ulcer / Q000188:drug therapy* / Q000453:epidemiology / Q000451:nursing; D012307:Risk Factors; D014945:Wound Healing / Q000187:drug effects
D004338:Drug Combinations; C072632:F 14001; D010919:Placebos; D010936:Plant Extracts; D002592:Cetomacrogol