Brain atrophy in Werdnig-Hoffmann disease.
CT scan imaging of the brain was done in eight children with Werdnig-Hoffmann Disease. Seven of them showed generalized cerebral cortical atrophy and one had low attenuated, non-enhancing areas in the white matter involving both frontal lobes. These changes could be due to repeated episodes of hypoxic injury.
Yohannan
M
M
Department of Paediatrics, King Khalid University Hospital, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Patel
P
P
Kolawole
T
T
Malabarey
T
T
Mahdi
A
A
D001284:Atrophy; D001921:Brain / Q000473:pathology*; D002508:Cephalometry; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009460:Neurologic Examination; D014897:Spinal Muscular Atrophies of Childhood / Q000473:pathology*; D014057:Tomography, X-Ray Computed