Caries incidence after topical application of varnishes containing different concentrations of sodium fluoride: 3-year results.
Previous studies have shown that topical application of the fluoride varnish Duraphat reduces caries incidence. The aim of the present study was to compare the caries inhibiting effect of a new fluoride varnish (Carex) containing 1.8% fluoride (F) with that of Duraphat (2.26% F). Informed consent was obtained from the guardians of 495 children 10-12 yr old in Voss Dental Health District (low F area). The children were randomly allocated to two groups. One group of subjects received 6-monthly application of Duraphat (n = 185), the other Carex (n = 165). Ethical considerations precluded the use of a placebo varnish. All participants received dental examinations including one pair of posterior bitewing radiographs and necessary dental care annually. One trained examiner interpreted bitewing radiographs blindly. Total 3-yr net DFS increment for 24 posterior approximal surfaces was 2.63 (SD = 3.81) in the Duraphat group and 2.12 (SD = 3.50) in the Carex group. DMFS increments based on 40 posterior occlusal and approximal surfaces were 5.21 (SD = 5.79) and 4.04 (SD = 4.92), respectively. Thus the results indicate a comparable efficacy for Carex and Duraphat at the caries activity level exhibited by these study participants.
Haugejorden
O
O
Department of Community Dentistry, University of Bergen, Norway.
Nord
A
A
D000704:Analysis of Variance; D002648:Child; D004245:DMF Index; D003731:Dental Caries / Q000517:prevention & control*; D005260:Female; D005460:Fluorides, Topical / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D015994:Incidence; D008297:Male; D010150:Paint; D010895:Pit and Fissure Sealants / Q000627:therapeutic use; D012737:Sex Factors; D012969:Sodium Fluoride / Q000627:therapeutic use*
C070175:Carex; D005460:Fluorides, Topical; D010895:Pit and Fissure Sealants; C023807:sodium fluoride topical preparation; D012969:Sodium Fluoride