title: [Hemostasis profiles in thrombotic disease].
abstract: It is well known that in thrombotic disease the alteration of biological factors such as antithrombin III, protein C, and protein S deficiency, and congenital disfibrinogenimias and displasminogenemias are determining factors being the acquired alterations not so well known. With this in mind was studied 85 patients with arterial thrombosis and 196 with venous thrombosis, who were again divided into three groups: unique or of repetition, less or more than 35 years and with or without immediate apparent cause. The general clinical-biological profile in patients with thrombosis in whom a congenital deficit is not detected, can help establish prognosis and treatment in these patients. In our patients, together with the importance of factors such as obesity, hyperlipemia, and tabaquism, an increase in fibrinogen (Fg), antigenic Factor VII (vWF:Ag), total protein S is observed as well as a decrease in total fibrinolytic activity related to an increase in the inhibitor of the plasminogen tissue activator (PTA).
authors.affiliation: Servicio de Hematología, Hospital Ramón y Cajal, Madrid.
authors.forename: A
authors.initials: A
authors.lastname: García Avello
authors.forename: L J
authors.initials: LJ
authors.lastname: García Frade
authors.forename: P
authors.initials: P
authors.lastname: Ortiz
authors.forename: M C
authors.initials: MC
authors.lastname: Torrado
authors.forename: J L
authors.initials: JL
authors.lastname: Navarro
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006487:Hemostasis; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013927:Thrombosis / Q000097:blood*
vernacular_title: Perfiles de hemostasia en la enfermedad trombótica.