Studies on the mutagenicity of hair dyes made in China.
A total of 13 commercial hair dye products made in China were tested for mutagenicity in 2 short-term bioassays, the histidine-requiring mutants of Salmonella typhimurium (strains TA98 and TA100) and the micronucleus test with mouse bone-marrow polychromatic erythrocyte cells in vivo. The results showed that the 13 hair dyes were not mutagenic in strains TA98 and TA100 with and without S-9. In the micronucleus test, no mutagenic effect was observed.
Wang
L L
LL
Institute of Environmental Health Monitoring, Chinese Academy of Preventive Medicine, Beijing.
Li
S L
SL
Qin
Y H
YH
Xu
F D
FD
Wang
Z S
ZS
Song
X D
XD
Li
J
J
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects; D001854:Bone Marrow Cells; D002681:China; D004912:Erythrocytes / Q000187:drug effects; D006202:Hair Dyes / Q000633:toxicity*; D008297:Male; D051379:Mice; D015162:Micronucleus Tests; D009152:Mutagenicity Tests / Q000379:methods; D009153:Mutagens / Q000633:toxicity*; D012486:Salmonella typhimurium / Q000235:genetics
D006202:Hair Dyes; D009153:Mutagens