title: [Intrathoracic and generalized granulomatosis in chronic diffuse liver diseases caused by the hepatitis B virus].
abstract: In 7 patients suffering from chronic diffuse liver diseases, they were combined with intrathoracic (3 patients) and generalized (4 patients) granulomatosis. Acute viral hepatitis or risk factors of infecting hepatitis viruses revealed in the case reports of 5 patients preceded the appearance of the signs of both lung and pulmonary damage. In 2 patients (without any indications in the case report to acute viral hepatitis and risk factors of infecting by hepatitis viruses) both the processes were established at a time. HBV markers were detected in all the 7 patients: in the blood serum in 3 and in the blood serum and liver tissue in 4 patients. Besides, HBsAg was identified in the smears of the lavage fluid sediment in 3 patients examined for that purpose. The role of HBV in both etiology of chronic diffuse liver diseases and granulomatosis is under discussion.
authors.forename: Z G
authors.initials: ZG
authors.lastname: Aprosina
authors.forename: A S
authors.initials: AS
authors.lastname: Drozdova
authors.forename: E A
authors.initials: EA
authors.lastname: Kogan
authors.forename: B M
authors.initials: BM
authors.lastname: Kornev
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D002908:Chronic Disease; D005260:Female; D006099:Granuloma / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D006509:Hepatitis B / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D006510:Hepatitis B Antibodies / Q000097:blood; D006511:Hepatitis B Antigens / Q000097:blood; D006521:Hepatitis, Chronic / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D013896:Thoracic Diseases / Q000097:blood / Q000175:diagnosis / Q000209:etiology*
chemical_list: D015415:Biomarkers; D006510:Hepatitis B Antibodies; D006511:Hepatitis B Antigens
vernacular_title: Vnutrigrudnoĭ i generalizovannyĭ granulematoz pri khronicheskikh diffuznykh zabolevaniiakh pecheni, obuslovlennykh virusom gepatita B.