[Variability of immune response in mice immunized at different time intervals after total or partial removal of organs with different reparative capacity].
The antibody response on sheep erythrocytes in the murine spleen at different time intervals after has been studied in one of the following operations: liver resection (70%), unilateral nephrectomy or sialadenectomy, or castration and bilateral sialadenectomy or castration. It was shown, that the liver and kidney surgery enhance the immune response if immunization was performed immediately or 24 h after the operation. Analogous changes of the immune response were observed under the immunization during 3 days after unilateral nephrectomy. The unilateral sialadenectomy evokes the contrary changes in immune response: immunization immediately or 24 h after the operation is accompanied by decrease of the above, the immunization on 3-7 days after the operation gets the increase of antibody genesis. Unilateral and bilateral castration as well as bilateral sialadenectomy evoke no changes of the immune response.
Babaeva
A G
AG
Arsent'eva
V V
VV
D000818:Animals; D000917:Antibody Formation; D007114:Immunization; D008099:Liver / Q000601:surgery*; D008297:Male; D051379:Mice; D009392:Nephrectomy; D009919:Orchiectomy; D011184:Postoperative Period; D012469:Salivary Glands / Q000601:surgery*; D013997:Time Factors
Variabel'nost' immunnogo otveta u mysheĭ, immunizirovannykh v raznye sroki posle polnogo i chastichnogo udaleniia tkani organov s neodinakovoĭ vosstanovitel'noĭ sposobnost'iu.