[The tumor as an atavistic adaptive reaction in environmental conditions].
In sponges, coelenterates, bryozoans, and ascidians, blastogenesis associated with the formation of resting buds and resting blastogenetic structures is similar to the oncogenesis. Just as the tumours, such buds and structures: 1) when released from control of the parent organism, developed independently of the latter and cause its destruction; 2) originate due to the action of various external and internal causes; 3) are hardy to anoxia, dehydration, overcooling; 4) consist of little differentiated and de-differentiated cells. These similarities can be explained in the frame of hypothesis which considers tumours an atavistic resting structure.
Makrushin
A V
AV
Khudoleĭ
V V
VV
D000222:Adaptation, Physiological; D000818:Animals; D005075:Biological Evolution; D002471:Cell Transformation, Neoplastic; D004777:Environment; D009369:Neoplasms / Q000209:etiology* / Q000503:physiopathology
Opukhol' kak atavisticheskaia adaptivnaia reaktsiia na usloviia okruzhaiushcheĭ sredy.