Reanalysis of epidemiological data for selenium anti-cancer activity.
Investigations of the health effects of selenium have repeatedly noted an inverse relationship of selenium (both soil and human sera) and decreased prevalence of cancer. This has been found in cross sectional, case-control and ecological study designs. Reanalysis of age-adjusted death rates by cancer site revealed a significant inverse relationship for lung and all cancer with blood selenium. Methodological problems in this type of research is discussed.
Lange
J H
JH
Center for Environmental and Occupational Training, Inc., East Pittsburgh, Pennsylvania 15112.
D016588:Anticarcinogenic Agents / Q000494:pharmacology*; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000401:mortality / Q000517:prevention & control*; D012643:Selenium / Q000494:pharmacology*
D016588:Anticarcinogenic Agents; D012643:Selenium