title: Effect of felodipine on histamine and adenosine induced bronchoconstriction in patients with asthma.
abstract: The effect of felodipine, a new selective calcium antagonist, was assessed on histamine and adenosine monophosphate (AMP) induced bronchoconstriction in 9 mild atopic asthmatics. Felodipine did not alter the baseline FEV1, but showed a small significant inhibitory effect upon histamine and AMP induced bronchoconstriction.
authors.affiliation: Department of Respiratory Medicine, Western Infirmary, Glasgow, Scotland, UK.
authors.forename: S K
authors.initials: SK
authors.lastname: Ghosh
authors.forename: P
authors.initials: P
authors.lastname: Rafferty
mesh_terms: D000249:Adenosine Monophosphate / Q000494:pharmacology; D000328:Adult; D001249:Asthma / Q000503:physiopathology*; D016084:Bronchoconstriction / Q000187:drug effects*; D004311:Double-Blind Method; D015736:Felodipine / Q000008:administration & dosage / Q000494:pharmacology*; D006632:Histamine / Q000494:pharmacology; D006801:Humans; D008297:Male
chemical_list: D000249:Adenosine Monophosphate; D006632:Histamine; D015736:Felodipine