title: Mechanism of analgesic effect of clonidine in the treatment of dysmenorrhea.
abstract: Clonidine substantially reduces the pain and cramping of dysmenorrhea. The mechanisms for this effect may lie in increased release of analgesic opioids. It is suggested that perhaps a thromboxane synthetase inhibitor such as ginger which activates endorphin receptors may also be an effective treatment.
authors.affiliation: Mount Pleasant Hospital Addiction Studies Foundation, Lynn, MA.
authors.forename: J
authors.initials: J
authors.lastname: Backon
mesh_terms: D000700:Analgesics / Q000627:therapeutic use; D003000:Clonidine / Q000627:therapeutic use*; D004412:Dysmenorrhea / Q000188:drug therapy* / Q000503:physiopathology; D004723:Endorphins / Q000378:metabolism; D005260:Female; D006801:Humans; D013930:Thromboxane-A Synthase / Q000037:antagonists & inhibitors
chemical_list: D000700:Analgesics; D004723:Endorphins; D013930:Thromboxane-A Synthase; D003000:Clonidine