Isolated liver perfusion versus hepatic artery infusion with 5-fluorouracil in a rat model; effects on thymidylate synthase.
Van der Wilt
C L
CL
Dept. Oncology, Free University Hospital, Amsterdam, The Netherlands.
Marinelli
A
A
Cloos
J
J
Smid
K
K
Pinedo
H M
HM
Peters
G J
GJ
D000818:Animals; D001665:Binding Sites; D001853:Bone Marrow / Q000187:drug effects / Q000201:enzymology; D002460:Cell Line; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000201:enzymology; D005468:Fluorodeoxyuridylate / Q000378:metabolism; D005472:Fluorouracil / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D007261:Infusions, Intra-Arterial; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008113:Liver Neoplasms / Q000188:drug therapy / Q000201:enzymology / Q000556:secondary*; D010477:Perfusion; D051381:Rats; D013940:Thymidylate Synthase / Q000378:metabolism*
D005468:Fluorodeoxyuridylate; D013940:Thymidylate Synthase; D005472:Fluorouracil