Acid proteinases of the fore-gut in metamorphosing tadpoles of Rana catesbeiana.
1. Two types of acid proteinases were found in the adult stomach of the bullfrog, Rana catesbeiana. 2. The first type of enzyme appeared in the developing stomach and esophagus and contained more than two kinds of acid proteinases. 3. These enzymes were identified as pepsin-type enzymes. 4. The second type of enzyme existed from the larva to adult stage and was also present in the adult duodenum. 5. This enzyme was different from pepsin and thought to be cathepsin E.
Inokuchi
T
T
Life Science Institute, Sophia University, Tokyo, Japan.
Kobayashi
K I
KI
Horiuchi
S
S
D000818:Animals; D002847:Chromatography, Agarose; D004064:Digestive System / Q000201:enzymology*; D010450:Endopeptidases / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D007814:Larva / Q000201:enzymology; D007976:Leupeptins / Q000494:pharmacology; D008970:Molecular Weight; D010436:Pepstatins / Q000494:pharmacology; D011892:Rana catesbeiana / Q000254:growth & development / Q000378:metabolism*
D007976:Leupeptins; D010436:Pepstatins; C014195:Streptomyces pepsin inhibitor; D010450:Endopeptidases; C032854:leupeptin; C031375:pepstatin