title: Application of single-photon emission computed tomography (SPECT) with 99mTc-MAA in evaluation of perfusion patterns during hepatic infusion chemotherapy.
abstract: In 6 patients receiving hepatic artery infusion chemotherapy for liver metastases, planar and single-photon emission computed tomography (SPECT) images of the abdomen were obtained after intravenous injection of 99mTc-phytate, and intra-catheter injection of 99mTc-MAA in the same geometrical settings. With this method, the three-dimensional intra- and extra-hepatic distribution of the agents during hepatic artery infusion chemotherapy can be evaluated.
authors.affiliation: Department of Radiology, Tokai University School of Medicine, Isehara, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Suzuki
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: S
authors.initials: S
authors.lastname: Yasuda
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000493:pharmacokinetics / Q000627:therapeutic use; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy; D005260:Female; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial; D007890:Leiomyosarcoma / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D012004:Rectal Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy; D013668:Technetium Tc 99m Aggregated Albumin; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D000970:Antineoplastic Agents; D013668:Technetium Tc 99m Aggregated Albumin