[The immunomodulators levamisole and dibazole in the prevention of acute postoperative pleural empyema as one method of preoperative preparation].
Numerous methodologies had been suggested to prevent postoperative pyothorax, but the tendency towards reduction in the incidence of this condition couldn't be seen. Forty patients with different lung diseases (malignant tumours, abscesses, bronchiectases) were examined. Twenty patients received low-dose levamisole and dibazole pre- and postoperatively, while to the remaining 20 patients these immunomodulators were not administered. All the 40 patients underwent radical operations. Immunoassay was undertaken in both groups in the preoperative period and at days 7, 14, and 21 postoperatively. As a result it was found that the group of patients devoid of immunoprophylaxis showed development of pyothorax in 5 percent of the cases. The groups of patients exposed to preventive measures including low doses of levamisole and dibazole did not show septic complications in the pleural cavity.
Uspenskiĭ
L V
LV
Belokrinitskiĭ
D V
DV
Pavlov
Iu V
IuV
Kudriashova
N M
NM
Sugova
L G
LG
Rumiantseva
E G
EG
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use*; D016724:Empyema, Pleural / Q000517:prevention & control*; D006801:Humans; D007978:Levamisole / Q000627:therapeutic use*; D008171:Lung Diseases / Q000601:surgery*; D011183:Postoperative Complications / Q000517:prevention & control*; D011292:Premedication
D000276:Adjuvants, Immunologic; D001562:Benzimidazoles; C004453:bendazole; D007978:Levamisole
Immunomoduliatory levamizol i diabazol v profilaktike ostrykh posleoperatsionnykh émpiem plevry kak odin i metodov predoperatsionnoĭ podgotovki.