Regulation of glycogen synthesis in human skeletal muscle: does cellular glycogen control glycogen synthase phosphatase activity?
Contrary to the accepted feedback control mechanism of glycogen biosynthesis in skeletal muscle, evidence is presented here leading to the conclusion that glycogen does not control the activity of glycogen synthase phosphatase in intact human skeletal muscle tissue.
Vardanis
A
A
Agriculture Canada, London Research Centre, Ontario.
Hudson
A J
AJ
D005246:Feedback; D006003:Glycogen / Q000096:biosynthesis* / Q000378:metabolism / Q000494:pharmacology; D006012:Glycogen Storage Disease Type V / Q000378:metabolism; D006007:Glycogen-Synthase-D Phosphatase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D006801:Humans; D009132:Muscles / Q000201:enzymology / Q000378:metabolism*
D006003:Glycogen; D006007:Glycogen-Synthase-D Phosphatase