Genetic markers in human hypertension.
A rapidly increasing abundance of genetic markers which can be characterized on a large scale makes an application of the genetic linkage strategy, so successful with Mendelian diseases, ever more attractive for genetic investigations of common diseases such as essential hypertension. Variability in expression, lack of phenotypic specificity and multiple causation create unique challenges when approaches originally designed for single gene inheritance are applied to disorders with complex determination.
Lalouel
J M
JM
Department of Human Genetics, Eccles Institute of Human Genetics, Salt Lake City, Utah 84112.
D005819:Genetic Markers / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000235:genetics*
D005819:Genetic Markers