Concentration and time dependent growth inhibition and metabolism in vitro by 2',2'-difluoro-deoxycytidine (gemcitabine).
Ruiz van Haperen
V W
VW
Dept. of Oncology, Free University Hospital, Amsterdam, The Netherlands.
Veerman
G
G
Noordhuis
P
P
Vermorken
J B
JB
Peters
G J
GJ
D000818:Animals; D000964:Antimetabolites, Antineoplastic / Q000494:pharmacology*; D001711:Biotransformation; D002294:Carcinoma, Squamous Cell; D002455:Cell Division / Q000187:drug effects*; D002460:Cell Line; D003110:Colonic Neoplasms; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D005260:Female; D006258:Head and Neck Neoplasms; D006801:Humans; D007700:Kinetics; D051379:Mice; D010051:Ovarian Neoplasms; D000093542:Gemcitabine
D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D000093542:Gemcitabine