title: [The value of computerized tomography and of the surgical assessment for lymph node staging in bronchial carcinoma. A prospective study].
abstract: We evaluated the accuracy of computed tomography (CT) and of surgical assessment for lymph node staging prospectively in 108 patients with bronchogenic carcinoma. For CT/surgical assessment a sensitivity of 29/90%, a specificity of 93/63%, a positive predictive value of 49/39% and a negative predictive value of 85/96% were calculated on a node-by-node basis. Sensitivity and specificity of CT were highly influenced by the lymph node region studied and by typing of the tumor. Adenocarcinomas showed a high proportion of normal-sized metastatic lymph nodes whereas squamous cell carcinomas exhibited a high proportion of enlarged tumor-free lymph nodes. The diagnostic accuracy in predicting the correct N-stage by CT was determined with 54% for squamous cell carcinoma and 56% for adenocarcinoma. The surgeon predicted the N-stage correctly in 39% of squamous cell carcinoma and 69% of adenocarcinoma. In conclusion, accuracy of CT-scan is too low to renounce mediastinoscopy for routine use in preoperative staging of bronchogenic carcinoma.
authors.affiliation: Chirurgische Klinik und Poliklinik, Universität München.
authors.forename: J R
authors.initials: JR
authors.lastname: Izbicki
authors.forename: O
authors.initials: O
authors.lastname: Thetter
authors.forename: T
authors.initials: T
authors.lastname: Kreusser
authors.forename: B
authors.initials: B
authors.lastname: Passlick
authors.forename: A
authors.initials: A
authors.lastname: Trupka
authors.forename: O
authors.initials: O
authors.lastname: Karg
authors.forename: D K
authors.initials: DK
authors.lastname: Wilker
authors.forename: L
authors.initials: L
authors.lastname: Schweiberer
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008482:Mediastinum; D008875:Middle Aged; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed
vernacular_title: Der Wert der Computertomographie und der chirurgischen Beurteilung für das Lymphknoten-Staging beim Bronchialcarcinom. Eine prospektive Studie.