[Effectiveness of immunomodulators in multimodal treatment of patients with lung cancer].
The analysis of clinical and immunologic findings indicate that retinol and decaris influence functional activity of immune cells at stage II of lung cancer irrespective of histological structure. In stage III, retinol induced changes in proportion of lymphocyte subpopulations, more evident in glandular cancer. Both immunomodulators lowered the number of purulent complications after surgical interventions. It is only retinol that influenced metastatic dissemination in lung cancer stage II-III.
Vagner
V P
VP
Voĭtkevich
E G
EG
Zakora
G I
GI
Chirvina
E D
ED
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000276:immunology / Q000601:surgery; D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000276:immunology / Q000601:surgery; D003131:Combined Modality Therapy; D004224:Diterpenes; D006801:Humans; D007978:Levamisole / Q000627:therapeutic use; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000276:immunology / Q000601:surgery; D016131:Lymphocyte Subsets / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011300:Preoperative Care; D000084562:Retinyl Esters; D014801:Vitamin A / Q000031:analogs & derivatives / Q000627:therapeutic use
D000276:Adjuvants, Immunologic; D004224:Diterpenes; D000084562:Retinyl Esters; D014801:Vitamin A; D007978:Levamisole; C009166:retinol acetate
Effektivnost' immunomoduliatorov pri kompleksnom lechenii bol'nykh rakom legkogo.