[Conformational analysis of lipotropic acton of human somatotropin and peptide analogs].
Based on the results of a semi-empirical analysis, several structural types of human and sea whale somatotropins and placental lactogen lipotropic actons which correspond, apparently, to the biologically active conformation common for the given molecular family, were identified. Chemical modification of human somatotropin lipotropic acton whose conformational possibilities selectively model the most preferential structure of the natural oligopeptide are proposed.
Mzareulov
K D
KD
D000595:Amino Acid Sequence; D000818:Animals; D013006:Growth Hormone / Q000031:analogs & derivatives / Q000737:chemistry*; D006801:Humans; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000737:chemistry; D010920:Placenta / Q000737:chemistry; D011487:Protein Conformation
D010446:Peptide Fragments; C037457:somatotropin (31-44); D013006:Growth Hormone
Konformatsionnyĭ analiz lipotropnogo aktona somatotropina cheloveka i peptidov-analogov.