[Conformation analysis of D-xylose-containing O-glycopeptide sequences].
The preferred conformations of the sequences of O-glycopeptides containing a beta-D-xylosyl group linked to an L-seryl residue, found in the N-terminus of proteodermatan sulfate, show an almost extended peptide chain with the sugar unit in a specific position. The results of force-field calculations with the AMBER program have been confirmed, by n.m.r.-spectroscopic experiments, for a minimum conformation.
Paulsen
H
H
Institut für Organische Chemie der Universität Hamburg, Deutschland.
Busch
R
R
Sinnwell
V
V
Pollex-Krüger
A
A
D000595:Amino Acid Sequence; D003871:Dermatan Sulfate / Q000031:analogs & derivatives / Q000737:chemistry; D006020:Glycopeptides / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D011487:Protein Conformation; D011509:Proteoglycans / Q000737:chemistry; D012984:Software; D014994:Xylose / Q000737:chemistry*
D006020:Glycopeptides; D011509:Proteoglycans; C028774:proteodermatan sulfate; D003871:Dermatan Sulfate; D014994:Xylose
Konformationsanalytische Untersuchungen von D-Xylose-haltigen O-Glycopeptidsequenzen.