[Assessment of interleukin-1 beta mRNA expression in the norm and pathology].
We investigated cytoplasmic RNA from the peripheral blood cells of pollinosis patients. Increased levels of IL-I mRNA were registered in neutrophils of patients suffering from pollinosis for a long time. Neutrophils from patients at the time of exacerbation of pollinosis responded to stimuli less than the cells from healthy donors. During remission the activated neutrophils from pollinosis patients and those from healthy donors had same levels of IL-I mRNA.
Kuprianova
O A
OA
Mordvinov
V A
VA
Ivanova
I P
IP
Krugleeva
O L
OL
Braga
E A
EA
Nosikov
V V
VV
Kozlov
V A
VA
Lozovoĭ
V P
VP
D003593:Cytoplasm / Q000737:chemistry; D006801:Humans; D007375:Interleukin-1 / Q000097:blood*; D009504:Neutrophils / Q000737:chemistry*; D009693:Nucleic Acid Hybridization; D012333:RNA, Messenger / Q000097:blood*; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology*
D007375:Interleukin-1; D012333:RNA, Messenger
Otsenka ékspressii mRNK interleĭkina-1beta v norme i pri patologii.