title: Low-power HeNe laser treatment of venous leg ulcers.
abstract: Clinical observations have suggested that low-energy lasers, mainly helium-neon (HeNe) lasers, might stimulate wound healing. A controlled study of the effects of low-power HeNe laser was performed in conjunction with a standard treatment for healing chronic venous leg ulcers on 46 patients divided randomly into two groups. All patients received standard treatment (paste-impregnated bandage and a self-adhesive elastic bandage) plus either HeNe laser (wave-length, 632.8 nm; beam power, 6 mW; continuous emission, energy density, 4 J/cm2) or placebo HeNe laser twice weekly for 12 weeks. The areas of healing were examined and compared percentage-wise after 2, 4, 6, 8, and 12 weeks. There were no significant differences in the proportion of healed ulcers or ulcer area in the HeNe group compared with the placebo group.
authors.affiliation: Department of Physiology, Karolinska Institute, Stockholm, Sweden.
authors.forename: T
authors.initials: T
authors.lastname: Lundeberg
authors.forename: M
authors.initials: M
authors.lastname: Malm
mesh_terms: D000328:Adult; D000368:Aged; D001458:Bandages / Q000592:standards; D003131:Combined Modality Therapy; D015444:Exercise; D005260:Female; D006801:Humans; D053685:Laser Therapy / Q000379:methods / Q000592:standards*; D007871:Leg Ulcer / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D014945:Wound Healing