title: Measurement of estrogen receptors in normal and neoplastic lymph node tissue from dogs.
abstract: Estrogen receptors were measured in normal canine lymph nodes and neoplastic tissue from dogs with lymphoma, using a commercially available [3H]estradiol dextran-coated charcoal assay. Using the same assay, estrogen receptors were detected in the positive-control tissues--dog uterus, rat uterus, and lyophilized bovine uterus. Specific binding of [3H]estradiol was not detected in rat skeletal muscle or in any of the canine lymphoid tissues, indicating that the specimens did not contain estrogen receptors.
authors.affiliation: Department of Veterinary Clinical Sciences, University of Illinois, Urbana 61801.
authors.forename: D S
authors.initials: DS
authors.lastname: Vicini
authors.forename: G K
authors.initials: GK
authors.lastname: Ogilvie
authors.forename: J
authors.initials: J
authors.lastname: Katzenellenbogen
authors.forename: K
authors.initials: K
authors.lastname: Carlson
mesh_terms: D000818:Animals; D001706:Biopsy / Q000662:veterinary; D002417:Cattle; D003600:Cytosol / Q000737:chemistry; D004283:Dog Diseases / Q000378:metabolism*; D004285:Dogs; D005260:Female; D008198:Lymph Nodes / Q000737:chemistry*; D008223:Lymphoma / Q000737:chemistry / Q000662:veterinary*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D011960:Receptors, Estrogen / Q000032:analysis*; D014599:Uterus / Q000737:chemistry
chemical_list: D011960:Receptors, Estrogen