title: Exploring the role of an endogenous caffeine-like substance in the pathogenesis of schizophrenia.
abstract: In a previous paper, I have proposed that the deficiency of an endogenous caffeine-like substance is the underlying pathogenic mechanism in schizophrenia (1). In the present paper, my new concept is used to explain many of the clinical, biochemical, radiologic and pharmacologic facts about schizophrenia.
authors.forename: S S
authors.initials: SS
authors.lastname: Missak
mesh_terms: D001921:Brain / Q000503:physiopathology*; D002110:Caffeine / Q000032:analysis* / Q000378:metabolism; D005260:Female; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000523:psychology; D011954:Receptors, Dopamine / Q000502:physiology; D012559:Schizophrenia / Q000209:etiology* / Q000503:physiopathology; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
chemical_list: D011954:Receptors, Dopamine; D002110:Caffeine; D005680:gamma-Aminobutyric Acid