title: Primary spinal malignant schwannoma: clinical, histological and cytogenetic findings.
abstract: Of the 19 patients who presented between 1980 and 1990 to the Department of Neurosurgery, University of Hamburg, F. R. G. with malignant schwannoma, 5 patients suffered from primary malignant spinal schwannoma (mean age 44 years, only one patient with von Recklinghausen's disease). Here we report the clinical, histological, and cytogenetic features of the five cases with primary malignant spinal schwannoma and discuss the prognostic aspects of this rare tumor.
authors.affiliation: Department of Neurosurgery, University Hospital Hamburg-Eppendorf, Fed. Rep. of Germany.
authors.forename: J M
authors.initials: JM
authors.lastname: Valdueza
authors.forename: C
authors.initials: C
authors.lastname: Hagel
authors.forename: M
authors.initials: M
authors.lastname: Westphal
authors.forename: M
authors.initials: M
authors.lastname: Hänsel
authors.forename: H D
authors.initials: HD
authors.lastname: Herrmann
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D002869:Chromosome Aberrations / Q000235:genetics; D005260:Female; D006801:Humans; D007621:Karyotyping; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009442:Neurilemmoma / Q000235:genetics / Q000473:pathology*; D009456:Neurofibromatosis 1 / Q000235:genetics / Q000473:pathology*; D013116:Spinal Cord / Q000473:pathology; D013117:Spinal Cord Compression / Q000235:genetics / Q000473:pathology; D013120:Spinal Cord Neoplasms / Q000235:genetics / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor