title: The reliability of the SADS-LA in a family study setting.
abstract: The joint-rater and test-retest reliability study of two translated versions of the SADS-LA (Schedule for Affective Disorders and Schizophrenia--Lifetime version--modified for the study of anxiety disorders), one in French and the other in German, have been tested in family study settings, in a sample of patients and first-degree relatives. The test-retest reliability study demonstrated that identification of major affective disorders and schizophrenia was performed with sufficient reliability; however, diagnoses of subtypes of major disorders (e.g. bipolar II disorder) and identification of minor disorders was less reliable. The implications of these findings in phenotype identification during family studies in psychiatry are discussed.
authors.affiliation: INSERM, Unité 155, Château de Longchamp, Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Leboyer
authors.forename: W
authors.initials: W
authors.lastname: Maier
authors.forename: M
authors.initials: M
authors.lastname: Teherani
authors.forename: D
authors.initials: D
authors.lastname: Lichtermann
authors.forename: T
authors.initials: T
authors.lastname: D'Amato
authors.forename: P
authors.initials: P
authors.lastname: Franke
authors.forename: J P
authors.initials: JP
authors.lastname: Lépine
authors.forename: J
authors.initials: J
authors.lastname: Minges
authors.forename: P
authors.initials: P
authors.lastname: McGuffin
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000175:diagnosis / Q000235:genetics* / Q000523:psychology*; D003866:Depressive Disorder / Q000175:diagnosis / Q000235:genetics* / Q000523:psychology*; D005260:Female; D005500:Follow-Up Studies; D008040:Genetic Linkage / Q000235:genetics; D006801:Humans; D008297:Male; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data*; D011594:Psychometrics; D011618:Psychotic Disorders / Q000175:diagnosis / Q000235:genetics* / Q000523:psychology*; D015203:Reproducibility of Results; D012559:Schizophrenia / Q000175:diagnosis / Q000235:genetics*; D012565:Schizophrenic Psychology