[The search for new antiparasitic agents. 4. The study of the antimalarial activity of N-(halogen naphthyloxy)-2-hydroxy-3,5-dihalogen benzamides].
Antimalarial activity of 10 N-(haloidnaphthyloxy)-2-hydroxy-3,5-dihaloidbenzamide compounds earlier synthesized as potential anthelmintics has been studied. It has been shown that antimalarial activity is typical only of amides of 2-hydroxy-3,5-diiodinebenzoic acid.
Mikhaĭlitsyn
F S
FS
Fedorova
O V
OV
Kozyreva
N P
NP
Lebedeva
M N
MN
Bolotina
L A
LA
Lychko
N D
ND
Menlisheva
F R
FR
D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use* / Q000633:toxicity; D001549:Benzamides / Q000627:therapeutic use* / Q000633:toxicity; D002738:Chloroquine / Q000031:analogs & derivatives / Q000627:therapeutic use; D004353:Drug Evaluation, Preclinical; D008288:Malaria / Q000188:drug therapy*; D051379:Mice; D010962:Plasmodium berghei
D000962:Antimalarials; D001549:Benzamides; C023676:chloroquine diphosphate; D002738:Chloroquine
Poisk novykh protivoparazitarnykh sredstv. Soobshchenie 4. Izuchenie protivomaliariĭnoĭ aktivnosti N-(galoidnaftiloksi)-2-gidroksi-3,5-digaloidbenzamidov.