IgA nephropathy in a child with human immunodeficiency virus type 1 infection.
Infection with the human immunodeficiency virus type 1 (HIV-1) can cause a spectrum of renal disease, termed acquired immunodeficiency syndrome (AIDS) nephropathy. The most common clinical manifestations of kidney involvement in HIV-1-infected patients are proteinuria and/or nephrotic syndrome, and the histopathological pattern usually reveals focal segmental glomerulosclerosis. We describe an 8-year-old child with AIDS who presented with recurrent gross hematuria. A kidney biopsy demonstrated IgA nephropathy. This unique case indicates that the range of kidney disease in HIV-infected children may be broader than originally thought, and that these patients warrant a complete evaluation of any renal abnormality.
Trachtman
H
H
Department of Pediatrics, Schneider Children's Hospital, New Hyde Park, New York 11042.
Gauthier
B
B
Vinograd
A
A
Valderrama
E
E
D001706:Biopsy; D002648:Child; D005922:Glomerulonephritis, IGA / Q000209:etiology* / Q000473:pathology; D015658:HIV Infections / Q000150:complications*; D015497:HIV-1; D006417:Hematuria / Q000209:etiology; D006801:Humans; D007668:Kidney / Q000473:pathology; D008297:Male