title: [Hepatic and renal transplantation in the treatment of type I hyperoxaluria].
abstract: Hyperoxaluria type I (HPI) is a metabolic disorder secondary to liver alanine glyoxylate aminotransferase deficiency. Renal failure occurs due to the excessive production and precipitation of oxalate in the kidney. Combined liver-renal transplantation is the correct treatment for this condition when end-stage renal failure occurs as with renal transplantation alone the risk of recurrence of the same pathology in the transplanted kidney would be high. We report the case of a 4 year-old child with HPI suffering from terminal renal failure in whom a hepato-renal transplantation was performed: six months later, creatinine clearance was 62 ml/min/1.73 m2 and liver function tests were normal.
authors.affiliation: Service de Réanimation Médicochirurgicale Pédiatrique Polyvalente, Hôpital des Enfants-Malades, Paris.
authors.forename: P
authors.initials: P
authors.lastname: Jouvet
authors.forename: P
authors.initials: P
authors.lastname: Hubert
authors.forename: D
authors.initials: D
authors.lastname: Jan
authors.forename: P
authors.initials: P
authors.lastname: Niaudet
authors.forename: A
authors.initials: A
authors.lastname: Beringer
authors.forename: C
authors.initials: C
authors.lastname: Narcy
authors.forename: M
authors.initials: M
authors.lastname: Daudon
authors.forename: M
authors.initials: M
authors.lastname: Broyer
authors.forename: Y
authors.initials: Y
authors.lastname: Revillon
mesh_terms: D000206:Actuarial Analysis; D003404:Creatinine / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006960:Hyperoxaluria, Primary / Q000097:blood / Q000150:complications / Q000601:surgery* / Q000652:urine; D007223:Infant; D007676:Kidney Failure, Chronic / Q000209:etiology; D016030:Kidney Transplantation; D008111:Liver Function Tests; D016031:Liver Transplantation
chemical_list: D003404:Creatinine
vernacular_title: Transplantation hépatique et rénale dans le traitement de l'hyperoxalurie de type I.