title: Alcoholism and depressive disorders in opioid addicts and their family members.
abstract: The co-occurrence of alcoholism and depression was examined in 201 opioid addicts and their 877 first-degree relatives using direct interviews and structured family history based on the Schedule for Affective Disorders and Schizophrenia (SADS) Research Diagnostic Criteria (RDC) method. Familial alcoholism was more frequent in alcoholic than nonalcoholic proband addicts, and primary depression was more frequent in relatives of depressed than nondepressed addicts. An association was suggested between secondary, but not primary, depression and alcoholism in females.
authors.affiliation: Substance Abuse Treatment Unit, Connecticut Mental Health Center, New Haven.
authors.forename: T R
authors.initials: TR
authors.lastname: Kosten
authors.forename: T A
authors.initials: TA
authors.lastname: Kosten
authors.forename: B J
authors.initials: BJ
authors.lastname: Rounsaville
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000235:genetics* / Q000523:psychology* / Q000534:rehabilitation; D016241:Child of Impaired Parents / Q000523:psychology*; D003866:Depressive Disorder / Q000235:genetics* / Q000523:psychology* / Q000534:rehabilitation; D005260:Female; D006801:Humans; D008297:Male; D009293:Opioid-Related Disorders / Q000235:genetics* / Q000523:psychology* / Q000534:rehabilitation; D010553:Personality Development; D012307:Risk Factors; D012737:Sex Factors; D012931:Social Environment