title: [Use of tuftsin in experimental leprosy].
abstract: The effect of tuftsin was studied in vivo using CBA mice infected with M. leprae by Shepard's technique and in vitro using macrophage-like cell line P. 388 (Co-cultivated with M. leprae) and the cultivated leproma tissue. It was found out that tuftsin acted as a stimulator of M. leprae multiplication in foot-pads of mice and as a prolongator of M. leprae survival in the cells of macrophage-like cell line P .388. It is concluded that using tuftsin might be useful in view of studying different aspects of experimental leprosy.
authors.forename: F E
authors.initials: FE
authors.lastname: Vishnevetskiĭ
authors.forename: I S
authors.initials: IS
authors.lastname: Freĭdlin
authors.forename: A A
authors.initials: AA
authors.lastname: Iushchenko
authors.forename: R F
authors.initials: RF
authors.lastname: Vishnevetskiĭ
authors.forename: V V
authors.initials: VV
authors.lastname: Anokhina
authors.forename: N G
authors.initials: NG
authors.lastname: Urliapova
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Iushin
authors.forename: I M
authors.initials: IM
authors.lastname: Eskina
mesh_terms: D000818:Animals; D002460:Cell Line; D003622:Dapsone / Q000627:therapeutic use; D007918:Leprosy / Q000188:drug therapy*; D051379:Mice; D008808:Mice, Inbred CBA; D009166:Mycobacterium leprae / Q000254:growth & development; D012293:Rifampin / Q000627:therapeutic use; D014405:Tuftsin / Q000627:therapeutic use*
chemical_list: D003622:Dapsone; D014405:Tuftsin; D012293:Rifampin
vernacular_title: Primenenie taftsina v éksperimental'noĭ leprologii.