Adrenocortical suppression presenting with agitated depression, morbid jealousy, and a dementia-like state.
A 66-year-old woman showed profound neuropsychiatric disturbance after withdrawal from prolonged corticosteroid treatment. Reintroduction of an alternative corticosteroid, at low dose, produced a return to premorbid mental state.
Hassanyeh
F
F
Department of Psychiatry, Royal Victoria Infirmary, Newcastle upon Tyne.
Murray
R B
RB
Rodgers
H
H
D000368:Aged; D017109:Akathisia, Drug-Induced; D001249:Asthma / Q000188:drug therapy; D003704:Dementia / Q000139:chemically induced* / Q000175:diagnosis / Q000523:psychology; D003866:Depressive Disorder / Q000139:chemically induced* / Q000175:diagnosis / Q000523:psychology; D005260:Female; D006801:Humans; D007578:Jealousy; D009483:Neuropsychological Tests; D011239:Prednisolone / Q000008:administration & dosage / Q000009:adverse effects; D011241:Prednisone / Q000008:administration & dosage / Q000009:adverse effects*; D011595:Psychomotor Agitation / Q000175:diagnosis / Q000523:psychology; D013375:Substance Withdrawal Syndrome / Q000175:diagnosis* / Q000523:psychology; D019966:Substance-Related Disorders / Q000175:diagnosis* / Q000523:psychology
D011239:Prednisolone; D011241:Prednisone