title: Epidemiology of diaphragmatic hernia in Languedoc-Roussillon.
abstract: The frequency of diaphragmatic hernia (DH) varies, according to the studies, between 1/2000 and 1/7000. In the Languedoc-Roussillon (South of France), due to the presence of a Regional Foeto-Pathology Department and Medico Surgical Paediatric Department, it was possible to itemize all of the DH over a 24 month period (June 1989----May 1991). 20 children presenting DH (10 foetuses and 10 liveborns) were examined for a total population of 49.350 foetuses and liveborns (frequency of DH: 0.40/1000). 10 DH were associated with extra-pulmonary malformations (50%). 4 chromosome abnormalities were found (20%). Prenatal chromosome analysis in cases of ultrasound malformation detection has increased the number of karyotype abnormalities diagnosed.
authors.affiliation: Unité de Génétique Médicale, Hôpital Saint-Charles, Montpellier.
authors.forename: P
authors.initials: P
authors.lastname: Sarda
authors.forename: P
authors.initials: P
authors.lastname: Devaux
authors.forename: G
authors.initials: G
authors.lastname: Lefort
authors.forename: C
authors.initials: C
authors.lastname: Humeau
authors.forename: D
authors.initials: D
authors.lastname: Rieu
mesh_terms: D002869:Chromosome Aberrations / Q000453:epidemiology; D025063:Chromosome Disorders; D005260:Female; D005313:Fetal Death / Q000453:epidemiology; D005602:France / Q000453:epidemiology; D005865:Gestational Age; D006548:Hernia, Diaphragmatic / Q000000981:diagnostic imaging / Q000453:epidemiology*; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male; D014463:Ultrasonography