title: The use of fibrin sealant in cerebrospinal fluid leakage.
abstract: Cerebrospinal fluid leakage is one of the central problems facing neurosurgeons, both due to its occasional difficulty in management and to the catastrophical significance of ensuing infection. An important tool emerging in the surgical management of CSF leakage is fibrin sealant, the natural coagulation product. Thirteen cases of CSF leakage, due to meningomyelocele, posttraumatic, and secondary to tumor, that were managed surgically with fibrin sealant are presented. Several of the cases were successfully operated upon following failure of conventional surgical techniques. Additional uses of fibrin sealant in neurosurgery are discussed.
authors.affiliation: Neurosurgery Department, Hadassah University Hospital, Jerusalem, Israel.
authors.forename: S
authors.initials: S
authors.lastname: Pomeranz
authors.forename: S
authors.initials: S
authors.lastname: Constantini
authors.forename: F
authors.initials: F
authors.lastname: Umansky
mesh_terms: D000236:Adenoma / Q000601:surgery*; D000328:Adult; D002555:Cerebrospinal Fluid; D002559:Cerebrospinal Fluid Rhinorrhea / Q000601:surgery*; D002675:Child, Preschool; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage*; D005402:Fistula / Q000601:surgery*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008591:Meningomyelocele / Q000601:surgery*; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000601:surgery*; D011183:Postoperative Complications / Q000601:surgery*; D012086:Reoperation; D012887:Skull Fractures / Q000601:surgery*
chemical_list: D015718:Fibrin Tissue Adhesive