[Ultrastructural and proliferation studies of human, catheter atherectomy extracted plaque material].
Atherectomy with a Simpson catheter enables a detailed characterization of percutaneously removed human atheromatous plaque material. Cell biological investigations (flow-cytometric analyses, cell type-specific antibodies, immunohistological labelling methods of selected extracellular matrix proteins) are aimed at a comparative characterization of excised material from primary lesions and restenoses to yield further insight into the mechanisms of plaque formation. First results on 17 specimens would like to contribute to a better understanding of the structure and composition of the extracellular matrix and their interaction with cells in atherosclerotic plaques.
Krings
W
W
Institut für Klinische Radiologie, Universitätsklinik Münster.
Schlumberger
W
W
Thie
M
M
Harrach
B
B
Robenek
H
H
Windmann
R
R
Rieser
R
R
Roth
F J
FJ
Peters
P E
PE
D000368:Aged; D000369:Aged, 80 and over; D001161:Arteriosclerosis / Q000473:pathology*; D002455:Cell Division / Q000502:physiology*; D002465:Cell Movement / Q000502:physiology*; D004691:Endarterectomy; D005260:Female; D005263:Femoral Artery / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009131:Muscle, Smooth, Vascular / Q000473:pathology*; D011150:Popliteal Artery / Q000473:pathology
Ultrastruktur- und Proliferationsuntersuchungen an humanem, durch Katheteratherektomie gewonnenem Plaquematerial.