[Diagnostic value of the deletion of the delta F508 gene in cystic fibrosis].
We have studied 70 carrier cystic fibrosis (CF) families with delta F508 mutation using the polymerase chain reaction (P.C.R.). We found that frequency of the mutation in CF chromosomes was 53%. 39% of carrier cystic fibrosis families were informative for the mutation.
Fernández García
E
E
Departamento de Genética, Fundación Jiménez Díaz, Madrid.
Nunes Martínez
V
V
Ibáñez Olias
M A
MA
Benítez Ortíz
J
J
D002648:Child; D002872:Chromosome Deletion; D003550:Cystic Fibrosis / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics*; D005787:Gene Frequency; D006801:Humans; D009154:Mutation; D010375:Pedigree; D013030:Spain / Q000453:epidemiology
Valor diagnóstico de la deleción delta F508 del gen de la fibrosis quística (FQ).