[The mechanism of the thymolytic action of anabolic steroids].
The administration of testosterone and metandrostenolone to male rats in doses of 10 and 20 mg/kg for 10 days produced a decrease of the thymus mass and a reduction of the thymic serum factor content. A phytoecdisteroid ecdisterone not possessing the androgenic activity fails to influence the thymus mass and the content of the thymic serum factor.
Semeĭkin
A V
AV
Stanevskaia
T Iu
TIu
Chermnykh
N S
NS
Sergeev
P V
PV
D045930:Anabolic Agents / Q000494:pharmacology*; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004441:Ecdysterone / Q000494:pharmacology; D008297:Male; D008696:Methandrostenolone / Q000494:pharmacology; D051379:Mice; D008810:Mice, Inbred C57BL; D009929:Organ Size / Q000187:drug effects; D051381:Rats; D013739:Testosterone / Q000494:pharmacology; D013935:Thymic Factor, Circulating / Q000032:analysis / Q000187:drug effects; D013950:Thymus Gland / Q000187:drug effects*; D013997:Time Factors
D045930:Anabolic Agents; D013739:Testosterone; D004441:Ecdysterone; D013935:Thymic Factor, Circulating; D008696:Methandrostenolone
Mekhanizm timoliticheskogo deĭstviia anabolicheskikh steroidov.