title: Mapping of human chromosome 5 microsatellite DNA polymorphisms.
abstract: Thirteen moderately to highly informative microsatellite DNA polymorphisms based on (dC-dA)n.(dG-dT)n repeats were mapped to segments of human chromosome 5 using both linkage analysis and a panel of somatic cell hybrids which contained rearranged chromosomes. The markers were distributed throughout most of the length of the chromosome from the regions p15.3-p15.1 to q33.3-qter. Maps of the sites of meiotic recombination within the reference families proved particularly useful for the purpose of integrating new polymorphisms into the existing linkage map.
authors.affiliation: Marshfield Medical Research Foundation, Wisconsin 54449.
authors.forename: J L
authors.initials: JL
authors.lastname: Weber
authors.forename: M H
authors.initials: MH
authors.lastname: Polymeropoulos
authors.forename: P E
authors.initials: PE
authors.lastname: May
authors.forename: A E
authors.initials: AE
authors.lastname: Kwitek
authors.forename: H
authors.initials: H
authors.lastname: Xiao
authors.forename: J D
authors.initials: JD
authors.lastname: McPherson
authors.forename: J J
authors.initials: JJ
authors.lastname: Wasmuth
mesh_terms: D001483:Base Sequence; D002874:Chromosome Mapping; D002895:Chromosomes, Human, Pair 5; D003001:Cloning, Molecular; D004276:DNA, Satellite / Q000235:genetics*; D005260:Female; D008040:Genetic Linkage / Q000235:genetics; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011995:Recombination, Genetic / Q000235:genetics
chemical_list: D004276:DNA, Satellite