title: Structural features of allergens large and small with emphasis on recombinant allergens.
abstract: The application of recombinant DNA techniques to the study of allergen structure has increased our knowledge of primary structures and B- and T-cell determinants. Thus, knowledge of the molecular bases of isoallergens and allergenic cross-reactivities is about to be rapidly expanded. Findings from the early applications of molecular cloning strategies to the study of some polypeptide allergens, together with a summary of our current knowledge of drug allergenic determinants, are presented here.
authors.affiliation: Royal North Shore Hospital of Sydney, New South Wales, Australia.
authors.forename: B A
authors.initials: BA
authors.lastname: Baldo
mesh_terms: D000485:Allergens / Q000737:chemistry* / Q000235:genetics; D000595:Amino Acid Sequence; D000818:Animals; D003001:Cloning, Molecular; D004274:DNA, Recombinant / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D011994:Recombinant Proteins / Q000737:chemistry* / Q000235:genetics
chemical_list: D000485:Allergens; D004274:DNA, Recombinant; D011994:Recombinant Proteins