[Sequential changes in free amino acid pool in burned rabbits].
Free amino acid (FAA) levels in plasma, erythrocytes, bone marrow, skeletal muscle, heart, liver, lung, brain, kidney and spleen were measured simultaneously in rabbits with burn injury. Results of study showed that, 86%-87% of skeletal muscle (remote from burn site), liver and lung FAA, 80%-82% of brain, bone marrow and erythrocyte FAA, 73% of heart, spleen and kidney FAA, and 57% of skeletal muscle (underneath the burn site) FAA varied in levels with the trends similar to that in plasma. These results suggest that the changes in profile of plasma free amino acids may essentially represent that of total amino acid pool after burn injury, and that the plasma amino acid kinetics seems to be a useful index for clinical study.
Li
J Y
JY
Trauma Center, Postgraduate Medical College, Beijing.
D000596:Amino Acids / Q000097:blood* / Q000378:metabolism; D000818:Animals; D002056:Burns / Q000097:blood* / Q000378:metabolism; D005260:Female; D008297:Male; D011817:Rabbits
D000596:Amino Acids