[Lithium carbonate augmentation in tricyclic antidepressant-resistant depression].
Combinations of lithium carbonate and tricyclic antidepressants are effective in the treatment of resistant unipolar depression. We present a case in which addition of lithium carbonate to a maximal dose of desipramine provided rapid and sustained improvement in a severely depressed 57-year-old woman. She had previously failed to respond to maximum doses of antidepressant drugs of 2 different classes. Although the lithium-tricyclic combination was successful in our case, we caution against its routine use.
Dorevitch
A
A
Talbieh Mental Health Center, Jerusalem.
Ginath
Y
Y
D000929:Antidepressive Agents, Tricyclic / Q000008:administration & dosage* / Q000627:therapeutic use; D003866:Depressive Disorder / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D016651:Lithium Carbonate / Q000008:administration & dosage* / Q000627:therapeutic use; D008875:Middle Aged
D000929:Antidepressive Agents, Tricyclic; D016651:Lithium Carbonate