Flunarizine in migraine prophylaxis: an Indian trial.
Flunarizine, a calcium channel blocker is considered useful in migraine prophylaxis. We report the first Indian trial with this drug. Fifteen patients with migraine were studied in a 6 months double-blind, placebo-controlled crossover trial. Flunarizine was superior to placebo in reducing the severity and duration of the individual attacks though there was no statistically significant effect on frequency of migraine attacks. The side effects most frequently caused by flunarizine were weight gain and daytime sleepiness.
Thomas
M
M
Department of Neurology, All India Institute of Medical Sciences, New Delhi.
Behari
M
M
Ahuja
G K
GK
D000328:Adult; D004341:Drug Evaluation; D005260:Female; D005444:Flunarizine / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008881:Migraine Disorders / Q000503:physiopathology / Q000517:prevention & control*; D010146:Pain
D005444:Flunarizine