title: [Possibility of directed changes in the surface activity of rat pulmonary surfactants by means of exposure to antibodies specific to them].
abstract: The experiments were performed on Wistar rats with weight of 150-200 g. Antibodies were prepared by immunization of rabbits with pure surfactants of rat lungs and were intravenously injected into rats three times within 3 days intervals. These antibodies were shown to influence the superficial activity of lung surfactants and the alveolar lung cells activity. The low doses of antibodies (0.06 micrograms of protein per 100 g of body mass) stimulated the superficial activity of lung surfactants, while higher doses (3 mg of protein per 100 g of body mass) inhibited it.
authors.forename: V A
authors.initials: VA
authors.lastname: Berezovskiĭ
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Gorchakov
authors.forename: I N
authors.initials: IN
authors.lastname: Alekseeva
authors.forename: E O
authors.initials: EO
authors.lastname: Bogomolets
authors.forename: I V
authors.initials: IV
authors.lastname: Andrianova
authors.forename: N V
authors.initials: NV
authors.lastname: Makogon
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology*; D011663:Pulmonary Surfactants / Q000276:immunology*; D011817:Rabbits; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D000911:Antibodies, Monoclonal; D011663:Pulmonary Surfactants
vernacular_title: Vozmozhnost' napravlennykh izmeneniĭ poverkhnostnoĭ aktivnosti surfaktantov legkogo krys putem vozdeĭstviia spetsificheskimi k nim antitelami.