title: Contributions to biorheology during hemodialysis.
abstract: Thrombogenicity is the property of a foreign surface to induce clotting processes or formation of aggregates after contact with blood. Beside the sort of anticoagulation patient's prethrombotic state, rheological factors as well as physicochemical properties of foreign membranes decisively influence thrombogenicity. We examined the influence of chronic renal failure and different hemodialyzers and blood transfusion therapy during hemodialysis on hemorheological parameters. Different membranes cannot be discriminated by the used hemorheological parameters. We clearly could demonstrate the close relationship between the hemofiltration rate and an increase of viscosity. Blood transfusion therapy or elevated hematocrit in combination with increased hemofiltration rate have influence on the flow behaviour of blood, especially in disturbed microcirculation.
authors.affiliation: Abt. für Klinische Hämostaseologie und Transfusionsmedizin, Unikliniken, Homburg/Saar, FRG.
authors.forename: U T
authors.initials: UT
authors.lastname: Seyfert
authors.forename: W
authors.initials: W
authors.lastname: Hauck
authors.forename: J
authors.initials: J
authors.lastname: Kirsch
authors.forename: H
authors.initials: H
authors.lastname: Kiesewetter
authors.forename: F W
authors.initials: FW
authors.lastname: Albert
authors.forename: E
authors.initials: E
authors.lastname: Wenzel
mesh_terms: D001672:Biocompatible Materials; D001769:Blood; D001803:Blood Transfusion; D001809:Blood Viscosity / Q000502:physiology; D005260:Female; D006440:Hemofiltration; D006801:Humans; D007676:Kidney Failure, Chronic / Q000503:physiopathology / Q000628:therapy; D008297:Male; D008567:Membranes, Artificial; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D006435:Renal Dialysis; D012212:Rheology
chemical_list: D001672:Biocompatible Materials; D008567:Membranes, Artificial