title: Studies on the antifertility components from Marsdenia koi.
abstract: By random screening test, Marsdenia koi was found to have antifertility activity on SD rat. From MeOH extracts of this plant two steroidal glycosides, marsdekoiside A and B, were isolated, and their structures were elucidated on the basis of spectral evidence and by comparison of the hydrolysis products with the authentic samples. Both are newly identified compounds, and marsdekoiside A has good antifertility activity.
authors.affiliation: Family Planning Research Institute, Tongji Medical University, Wuhan.
authors.forename: J L
authors.initials: JL
authors.lastname: Yuan
authors.forename: W P
authors.initials: WP
authors.lastname: Ding
authors.forename: J P
authors.initials: JP
authors.lastname: Shi
authors.forename: Z Z
authors.initials: ZZ
authors.lastname: Lu
authors.forename: B N
authors.initials: BN
authors.lastname: Zhou
authors.forename: C A
authors.initials: CA
authors.lastname: Erdelmeier
authors.forename: G A
authors.initials: GA
authors.lastname: Cordell
authors.forename: H H
authors.initials: HH
authors.lastname: Fong
authors.forename: N R
authors.initials: NR
authors.lastname: Farnsworth
mesh_terms: D000818:Animals; D003271:Contraceptive Agents, Female / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D005260:Female; D011278:Pregnanes; D051381:Rats; D011919:Rats, Inbred Strains; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D003271:Contraceptive Agents, Female; D004365:Drugs, Chinese Herbal; D011278:Pregnanes; D012503:Saponins; C072846:marsdekoiside B; C072845:marsdekoiside A