[A new method of the evaluation of lymphocytes and monocytes during immune response in patients with tuberculosis and sarcoidosis].
Examination which included 21 patients with tuberculosis, 6 with sarcoidosis and 9 healthy volunteers was aimed at determining the amount and intensity of surface fluorescence of CD+3, CD+4, CD+8 lymphocytes and CD14+, KIM+I monocytes. The findings demonstrate that determination of the fluorescence intensity of lymphocytes and monocytes provides a more exact characterization of the morphofunctional state of cells involved in the immune response. It is shown in particular that tuberculosis and sarcoidosis patients exhibit a varying density of the expressed antigenic markers of lymphocytes, which increases only in sarcoidosis, except a suppressor subpopulation (cytotoxic lymphocytes). Patients with tuberculosis had decreased density of CD9+, CD14+ and KIMI markers on the particular subpopulations.
Averbakh
M M
MM
Khomenko
I S
IS
Gergert
V Ia
VIa
D000328:Adult; D005453:Fluorescence; D006801:Humans; D008171:Lung Diseases / Q000276:immunology*; D016131:Lymphocyte Subsets / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology*; D009000:Monocytes / Q000276:immunology*; D012507:Sarcoidosis / Q000276:immunology*; D014376:Tuberculosis / Q000276:immunology*
Novyĭ metod otsenki sostoianiia limfotsitov i monotsitov v protsesse immunnogo otveta u bol'nykh tuberkulezom i sarkoidozom.