title: IgA nephropathy in a child with human immunodeficiency virus type 1 infection.
abstract: Infection with the human immunodeficiency virus type 1 (HIV-1) can cause a spectrum of renal disease, termed acquired immunodeficiency syndrome (AIDS) nephropathy. The most common clinical manifestations of kidney involvement in HIV-1-infected patients are proteinuria and/or nephrotic syndrome, and the histopathological pattern usually reveals focal segmental glomerulosclerosis. We describe an 8-year-old child with AIDS who presented with recurrent gross hematuria. A kidney biopsy demonstrated IgA nephropathy. This unique case indicates that the range of kidney disease in HIV-infected children may be broader than originally thought, and that these patients warrant a complete evaluation of any renal abnormality.
authors.affiliation: Department of Pediatrics, Schneider Children's Hospital, New Hyde Park, New York 11042.
authors.forename: H
authors.initials: H
authors.lastname: Trachtman
authors.forename: B
authors.initials: B
authors.lastname: Gauthier
authors.forename: A
authors.initials: A
authors.lastname: Vinograd
authors.forename: E
authors.initials: E
authors.lastname: Valderrama
mesh_terms: D001706:Biopsy; D002648:Child; D005922:Glomerulonephritis, IGA / Q000209:etiology* / Q000473:pathology; D015658:HIV Infections / Q000150:complications*; D015497:HIV-1; D006417:Hematuria / Q000209:etiology; D006801:Humans; D007668:Kidney / Q000473:pathology; D008297:Male