title: Continuous subarachnoid analgesia in two adolescents with severe scoliosis and impaired pulmonary function.
abstract: We report postoperative pain management of two adolescents after upper abdominal procedures, one with Hurler-Scheie syndrome and a second with Duchenne muscular dystrophy, and both had progressive spinal scoliosis with poor pulmonary function. A combined technique of subarachnoid and general anesthesia was used during surgery. Postoperative administration of small intermittent doses of subarachnoid morphine produced profound analgesia, which eliminated the need for systemic opioids, restored preoperative arterial oxygenation within 48 hours after the operation, and expedited postoperative recovery.
authors.affiliation: Department of Anesthesia, Children's Hospital, Boston, MA 02115.
authors.forename: N F
authors.initials: NF
authors.lastname: Sethna
authors.forename: C B
authors.initials: CB
authors.lastname: Berde
mesh_terms: D000005:Abdomen / Q000601:surgery*; D000293:Adolescent; D006801:Humans; D008297:Male; D009020:Morphine / Q000008:administration & dosage*; D008059:Mucopolysaccharidosis I / Q000150:complications*; D009136:Muscular Dystrophies / Q000150:complications*; D010149:Postoperative Pain / Q000517:prevention & control*; D012120:Respiration Disorders / Q000150:complications*; D012600:Scoliosis / Q000150:complications*; D013346:Subarachnoid Space
chemical_list: D009020:Morphine