[Opiate analgesia in labor--use of nalbuphine in comparison with administration of the combination Dolantin/Atosil/Haldol].
Since July 1, 1990, Nalbuphine has been used as an obstetric analgesia at the Municipal Women's Hospital in Cologne-Holweide. The following differences were found between 2 groups of 122 patients each, one of which received Nalbuphine and the other a socalled cocktail, a combination of dolantin, haldol, and atosil. The number of spontaneous births in the Nalbuphine group was higher and the number of Caesarean sections and vagino-operative births were lower in comparison to the cocktail group. The pH-level of the arterial umbilical cord was higher in the Nalbuphine group, which can be explained by less stress on the child during birth. Overall, the post partum irregularities were less in the Nalbuphine group, whereas 6 children in the cocktail group had respiratory adaptation disturbances.
Schwickerath
J
J
Frauenklinik der Krankenanstalten der Stadt Köln, Köln-Holweide.
Wolff
F
F
D016362:Analgesia, Obstetrical / Q000379:methods*; D004359:Drug Therapy, Combination; D005113:Extraction, Obstetrical; D005260:Female; D006220:Haloperidol / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D007231:Infant, Newborn; D007273:Injections, Intramuscular; D008431:Maternal-Fetal Exchange / Q000187:drug effects; D008614:Meperidine / Q000008:administration & dosage* / Q000009:adverse effects; D009266:Nalbuphine / Q000008:administration & dosage* / Q000009:adverse effects; D010147:Pain Measurement; D011247:Pregnancy; D011256:Pregnancy Outcome; D011398:Promethazine / Q000008:administration & dosage* / Q000009:adverse effects; D014590:Uterine Contraction / Q000187:drug effects
D008614:Meperidine; D011398:Promethazine; D006220:Haloperidol; D009266:Nalbuphine
Opiatanalgesie unter der Geburt--Einsatz von Nalbuphin im Vergleich zu der Gabe einer Kombination von Dolantin/Atosil/Haldol.