[Beneficial effect of diltiazem on pulmonary hypertension in a patient with Hughes-Stovin's syndrome].
A 54 year-old female who had a history of hemoptysis was admitted to our hospital because of dyspnea on effort. Pulmonary arterial pressure was elevated and pulmonary arteriography showed multiple pulmonary arterial aneurysms and occlusion of the left upper lobe pulmonary artery. Systolic pulmonary arterial pressure was 110 mmHg when measured by continuous wave Doppler echocardiography. From the clinical and angiographical findings, we diagnosed this patient as having Hughes-Stovin's syndrome (forme fruste). 30 mg of diltiazem per day was initially used, and 80 mg was used thereafter. After 2 months follow up of the medication with diltiazem, systolic pulmonary arterial pressure decreased from 110 mmHg to 61 mmHg and clinical symptoms improved dramatically.
Wakamiya
R
R
Second Department of Internal Medicine, Ehime University School of Medicine.
Fujiwara
Y
Y
Hamada
M
M
Hiwada
K
K
Ishikawa
K
K
Watanabe
J
J
D000783:Aneurysm / Q000150:complications*; D004110:Diltiazem / Q000627:therapeutic use*; D005260:Female; D006469:Hemoptysis / Q000150:complications; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy* / Q000209:etiology; D008875:Middle Aged; D011651:Pulmonary Artery; D011655:Pulmonary Embolism / Q000150:complications*; D013577:Syndrome
D004110:Diltiazem