[Multiple liver abscesses in chronic granulomatosis].
We report on a case of a three year old boy, suffering from chronic granulomatosis disease, which led to repeated bacterial infections and finally to multiple liver abscesses. Diagnosis was based on the nitroblue-tetrazolium-test and histology. Antibiotic therapy over many weeks was not successful in spite of an adequate choice of medication against staphylococcal microorganisms and of good intracellular penetration, applicated parenterally. Only treatment by chloramphenicol after previous surgical drainage of the abscesses led to a dramatic clinical improvement and regression of the liver abscesses. The subsequent chemoprophylaxis with trimethoprim/sulfamethoxazole for at lest two years left the patient without clinical symptoms.
Oswald
H P
HP
Universitäts-Kinderklinik, Innsbruck.
Fischer
H
H
Menardi
G
G
Gschnitzer
F
F
Könner
C
C
D000900:Anti-Bacterial Agents; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D006105:Granulomatous Disease, Chronic / Q000175:diagnosis / Q000235:genetics*; D006801:Humans; D008100:Liver Abscess / Q000175:diagnosis / Q000235:genetics* / Q000601:surgery; D008297:Male; D009580:Nitroblue Tetrazolium; D014057:Tomography, X-Ray Computed
D000900:Anti-Bacterial Agents; D009580:Nitroblue Tetrazolium
Multiple Leberabszesse bei chronischer Granulomatose.