Plasma histamine levels in laminitic horses and in horses treated with a corticosteroid.
In seven sound horses histamine plasma levels were evaluated by means of a radioenzymatic method using the enzyme histamine-N-methyltransferase (mean = 4.46 nmol/l, SD = 1.55 nmol/l). Histamine levels of laminitic horses were significantly higher (n = 11; mean = 12.46 nmol/l, SD = 3.24 nmol/l). In three sound horses plasma histamine levels were determined over a two week period following a double administration of 10 mg dexamethasone-21-isonicotinate/100 kg body weight. Histamine levels remained within the range of sound control horses.
Rautschka
R
R
Clinic of Orthopaedics in Ungulates, University of Veterinary Medicine, Vienna, Austria.
Stanek
C
C
Knezevic
P F
PF
D000818:Animals; D003907:Dexamethasone / Q000494:pharmacology*; D005260:Female; D005534:Foot Diseases / Q000097:blood / Q000662:veterinary; D006632:Histamine / Q000097:blood*; D006724:Hoof and Claw / Q000473:pathology*; D006734:Horse Diseases / Q000097:blood*; D006736:Horses / Q000097:blood*; D008297:Male
D003907:Dexamethasone; D006632:Histamine