title: [Protective effect of anti-staphylococcal immunosorbent on the phenotype of lymphocyte membrane in diffuse Staphylococcus-Pseudomonas peritonitis].
abstract: An antistaphylococcal and an antitetanic immunosorbents on a silica carrier were tested in diffuse staphylococcal pyocyanic peritonitis to protect receptor expression on the general T and B lymphocyte populations and of Fc-receptors to IgM, IgG and IgA. Plasma of animals with peritonitis was shown to exert a powerful suppressive effect on lymphocyte receptors. Perfusion of toxic plasma over the antistaphylococcal immunosorbents resulted in specific adsorption of microbial toxins and completely prevented Fc gamma-, Fc mu- and Fc alpha-receptor expression on cells. Plasma treated with the antitetanic immunosorbent retained suppressive effects. The low protection of receptors may be explained by nonspecific adsorption of texins.
authors.forename: I N
authors.initials: IN
authors.lastname: Bol'shakov
authors.forename: D V
authors.initials: DV
authors.lastname: Kulaev
authors.forename: O V
authors.initials: OV
authors.lastname: Silant'eva
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Lopukhin
mesh_terms: D000818:Animals; D001427:Bacterial Toxins / Q000302:isolation & purification; D002462:Cell Membrane / Q000276:immunology; D004195:Disease Models, Animal; D006464:Hemoperfusion; D007163:Immunosorbent Techniques; D007164:Immunosorbents / Q000627:therapeutic use*; D010538:Peritonitis / Q000235:genetics / Q000276:immunology / Q000382:microbiology / Q000628:therapy*; D010641:Phenotype; D011552:Pseudomonas Infections / Q000150:complications / Q000235:genetics / Q000276:immunology / Q000628:therapy*; D051381:Rats; D013203:Staphylococcal Infections / Q000150:complications / Q000235:genetics / Q000276:immunology / Q000628:therapy*; D013211:Staphylococcus aureus / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D001427:Bacterial Toxins; D007164:Immunosorbents
vernacular_title: Protektivnyĭ éffekt protivostafilokokkovogo immunosorbenta na fenotip kletochnoĭ poverkhnosti limfotsitov pri razlitom stafilokokko-sinegnoĭnom peritonite.