[The transplacental effect of methylmercury on the chromosome of embryo liver cells in rat].
The effect of methylmercury on the chromosome of embryo liver cells of rat was studied in vivo. The results showed that the rate of chromosome aberration both of embryo liver cells and maternal bone marrow cells increased linearly with the dose of methylmercury. The linear equations were as follows: Yembryo liver cell = 10.30 + 2.54D (r = 0.9573, P less than 0.01) Ymarrow cell = 2.34 + 0.71D (r = 0.9782, P less than 0.01).
Li
Y H
YH
School of Preventive Medicine, Norman Bethune University of Medical Sciences, Changchun.
Lin
X W
XW
D000818:Animals; D001853:Bone Marrow / Q000648:ultrastructure; D002869:Chromosome Aberrations; D004305:Dose-Response Relationship, Drug; D004622:Embryo, Mammalian; D005260:Female; D008099:Liver / Q000648:ultrastructure*; D008431:Maternal-Fetal Exchange; D008767:Methylmercury Compounds / Q000633:toxicity*; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains
D008767:Methylmercury Compounds