[Activation of respiratory sinus arrhythmia in monkeys during space flight].
During the first day in space the rhesus monkey, called Vernyi, flown on Cosmos-1667 showed higher values of the daytime, night, and daily respiratory sinus arrhythmia (RSA) when compared to those observed before launch and before or the first day of a simulation study. During orbital flight, the mean daily value of RSA was in the range 13.08-16.00 beats/min. In the simulation study, this parameter increased from 4.68 beats/min during the first day to 15.16 beats/min on the 6th day. The mean RSA values during days 1 through 3 were significantly higher in real than in simulation flight. Analysis of rheopneumograms revealed a correlation between respiration parameters and RSA variations. In space, there was no correlation between RSA and HR, which was reported in the simulation study (r = -0.625). Assuming that RSA is a noninvasive indicator of parasympathetic control over cardiac rhythm, it can be postulated that the primate body adapted to microgravity via activation of parasympathetic mechanisms controlling the heart function.
Mel'nichenko
V P
VP
Badakva
A M
AM
Evstratov
Iu A
IuA
Drozdov
I N
IN
Magedov
V S
VS
D000818:Animals; D002940:Circadian Rhythm / Q000502:physiology; D004195:Disease Models, Animal; D008168:Lung / Q000294:innervation*; D008253:Macaca mulatta / Q000502:physiology*; D012143:Respiratory Physiological Phenomena; D012804:Sick Sinus Syndrome / Q000209:etiology*; D012849:Sinoatrial Node / Q000503:physiopathology*; D013026:Space Flight; D013997:Time Factors; D014630:Vagus Nerve / Q000503:physiopathology*; D014893:Weightlessness / Q000009:adverse effects*
Aktivatsiia respiratornoĭ sinusovoĭ aritmii u obez'iany v kosmicheskom polete.