The use of immunosuppressive drugs in kidney transplantation.
The proper management of immunosuppression in transplantation requires a working knowledge of immunology and pharmacology. In practice we employ two to four agents in one of several complicated protocols. If we consider the variability of individual patients, the potential for drug interactions, and significant compliance problems inherent in any long-term multidrug regimen, the dimensions of the challenge of immunosuppression to the practicing clinician become apparent.
Salomon
D R
DR
Laboratory of Immunology, National Institute of Allergy and Infectious Diseases, National Institute of Health, Bethesda, MD 20892.
D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006084:Graft Rejection / Q000187:drug effects; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D016030:Kidney Transplantation
D000911:Antibodies, Monoclonal; D007166:Immunosuppressive Agents