Naphthol and lens.
Alpha and beta naphthols, the metabolites of naphthalene, a cataractogenic agent, was tested for it's effect on sheep lens proteases and their inhibitors. It reduced protease activities, not that of inhibitor activities of lens proteins. It also increased the efflux of free amino acid from lenses which was retarded by a high concentration of tissue galactose.
Murthy
M S
MS
Dept. of Biochemistry, Department of Atomic Energy Hospital, Kalpakkam.
D000596:Amino Acids / Q000378:metabolism; D000818:Animals; D002386:Cataract / Q000139:chemically induced; D003470:Culture Media; D005690:Galactose / Q000494:pharmacology; D007908:Lens, Crystalline / Q000187:drug effects* / Q000378:metabolism; D009284:Naphthols / Q000494:pharmacology*; D011188:Potassium / Q000378:metabolism; D012756:Sheep
D000596:Amino Acids; D003470:Culture Media; D009284:Naphthols; D011188:Potassium; D005690:Galactose