Determination of levamisole and thiabendazole in meat by HPLC and photodiode array detection.
An HPLC method for the analysis of levamisole and thiabendazole has been developed with recoveries varying over 63-75%. The two anthelmintics are extracted from meat with ethyl acetate, purified by liquid/liquid extraction and analyzed quantitatively on a mu Bondapak C18 column. The optimum detection is achieved by means of a photodiode array detector at 240 nm for levamisole and at 300 nm for thiabendazole. The detection limits for both compounds in meat are 25 micrograms/kg and 5 micrograms/kg, respectively.
Wyhowski de Bukanski
B
B
Ministère de la Santé Publique et de l'Environnement, Bruxelles, Belgium.
Degroodt
J M
JM
Beernaert
H
H
D000818:Animals; D002851:Chromatography, High Pressure Liquid; D004350:Drug Residues / Q000032:analysis*; D007978:Levamisole / Q000032:analysis*; D008460:Meat / Q000032:analysis*; D015203:Reproducibility of Results; D013827:Thiabendazole / Q000032:analysis*
D007978:Levamisole; D013827:Thiabendazole