A study of the effect of perchloroethylene exposure on the reproductive outcomes of wives of dry-cleaning workers.
The purpose of this investigation was to compare the reproductive outcomes of wives of men exposed to perchloroethylene in the dry-cleaning industry compared to those of wives of laundry workers. Seventeen female partners of dry cleaners and 32 partners of laundry workers were interviewed. The number of pregnancies and the standardized fertility ratios were similar between the two groups. Wives of dry cleaners did not have higher rates of spontaneous abortions. However, wives of dry cleaners were more than twice as likely to have a history of attempting to become pregnant for more than 12 months or to have sought care for an infertility problem. Cox proportional hazards models indicated that dry-cleaners' wives had half of the per-cycle pregnancy rate of wives of laundry workers, when controlling for other potential confounders (estimated rate ratio of 0.54, 95% C.I. = 0.23, 1.27).
Eskenazi
B
B
Program of Maternal and Child Health, School of Public Health, University of California, Berkeley 94720.
Fenster
L
L
Hudes
M
M
Wyrobek
A J
AJ
Katz
D F
DF
Gerson
J
J
Rempel
D M
DM
D000328:Adult; D005260:Female; D005298:Fertility / Q000187:drug effects*; D005306:Fertilization / Q000187:drug effects*; D006801:Humans; D007846:Laundering; D008393:Marriage; D016273:Occupational Exposure / Q000009:adverse effects; D011247:Pregnancy; D011256:Pregnancy Outcome; D016016:Proportional Hazards Models; D013750:Tetrachloroethylene / Q000494:pharmacology*; D013997:Time Factors
D013750:Tetrachloroethylene