title: The natural history and results of surgery in 50 cases of syringomyelia.
abstract: In recent years, new neuroimaging techniques have revived interest in syringomyelia with respect to indications and results of surgery. Fifty patients, 36 of whom underwent surgery, have been reviewed. All patients but 3 underwent a new clinical assessment and 33 of them were also neurophysiologically investigated. In approximately one-third of the non-surgically treated patients the clinical course was benign. In 26 of the surgically treated patients an improvement was noted at the short-term assessment both for spasticity and pain, but in most of them it was not maintained in the medium term. Therefore, an accurate selection of the patients to be treated surgically is strongly recommended, particularly when the natural history of the disease is considered. Decompression of the posterior fossa seems to give the best results, yet no curative surgical treatment has been devised to date.
authors.affiliation: Institute of Clinical Neurology, University of Milan, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Mariani
authors.forename: M G
authors.initials: MG
authors.lastname: Cislaghi
authors.forename: S
authors.initials: S
authors.lastname: Barbieri
authors.forename: F
authors.initials: F
authors.lastname: Filizzolo
authors.forename: F
authors.initials: F
authors.lastname: Di Palma
authors.forename: E
authors.initials: E
authors.lastname: Farina
authors.forename: G
authors.initials: G
authors.lastname: D'Aliberti
authors.forename: G
authors.initials: G
authors.lastname: Scarlato
mesh_terms: D000293:Adolescent; D000328:Adult; D001139:Arnold-Chiari Malformation / Q000150:complications; D004576:Electromyography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009192:Myelography; D012008:Recurrence; D012189:Retrospective Studies; D013595:Syringomyelia / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000473:pathology / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome