Measurement of estrogen receptors in normal and neoplastic lymph node tissue from dogs.
Estrogen receptors were measured in normal canine lymph nodes and neoplastic tissue from dogs with lymphoma, using a commercially available [3H]estradiol dextran-coated charcoal assay. Using the same assay, estrogen receptors were detected in the positive-control tissues--dog uterus, rat uterus, and lyophilized bovine uterus. Specific binding of [3H]estradiol was not detected in rat skeletal muscle or in any of the canine lymphoid tissues, indicating that the specimens did not contain estrogen receptors.
Vicini
D S
DS
Department of Veterinary Clinical Sciences, University of Illinois, Urbana 61801.
Ogilvie
G K
GK
Katzenellenbogen
J
J
Carlson
K
K
D000818:Animals; D001706:Biopsy / Q000662:veterinary; D002417:Cattle; D003600:Cytosol / Q000737:chemistry; D004283:Dog Diseases / Q000378:metabolism*; D004285:Dogs; D005260:Female; D008198:Lymph Nodes / Q000737:chemistry*; D008223:Lymphoma / Q000737:chemistry / Q000662:veterinary*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D011960:Receptors, Estrogen / Q000032:analysis*; D014599:Uterus / Q000737:chemistry
D011960:Receptors, Estrogen