Angiotropic lymphoma (malignant angioendotheliomatosis) presenting with rapidly progressive dementia.
An 87-year-old male presented with rapidly progressive dementia, disorder of consciousness and myoclonus, suggesting Creutzfeldt-Jakob disease, but with nonspecific EEG and negative CT findings. Autopsy revealed a malignant angiotropic lymphoma with accumulation of tumor cells within small vessels of the brain and visceral organs. Immunohistochemistry disclosed a large cell lymphoma of B cell type.
Drlicek
M
M
Pathologisch-bakteriologisches Institut, Psychiatrisches Krankenhaus, Wien, Austria.
Grisold
W
W
Liszka
U
U
Hitzenberger
P
P
Machacek
E
E
D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000473:pathology*; D002102:Cadaver; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis; D003704:Dementia / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006390:Hemangioendothelioma / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology; D008297:Male; D014781:Viscera / Q000098:blood supply