title: Recently characterized vascular tumours of skin and soft tissues.
abstract: This review summarizes the clinicopathological features of a number of vascular tumours that have been characterized only in recent years. These include: glomeruloid haemangioma, a multifocal vascular lesion associated with POEMS syndrome: Kaposi-like infantile haemangioendothelioma, a borderline malignant tumour occurring in the retroperitoneum of infants, mimicking Kaposi's sarcoma histologically; giant cell angioblastoma, characterized by proliferated vessels with a granuloma-like appearance; benign lymphangioendothelioma (progressive lymphangioma), slowly-growing macule or plaque over the trunk or limb, mimicking low-grade angiosarcoma histologically; targetoid haemosiderotic haemangioma, a benign lesion with a distinctive annular appearance and histologically overlapping with benign lymphangioendothelioma; spindle cell haemangioendothelioma, a lesion located mostly in the distal extremities, characterized by cavernous vascular spaces, spindle cells with interspersed narrow vascular channels and scattered plump vacuolated endothelial cells; acquired tufted angioma, characterized by 'cannon-ball' involvement of the dermis by lobules of pericyte-rich capillaries; sinusoidal haemangioma, a distinctive variant of cavernous haemangioma which may be confused with angiosarcoma; and epithelioid angiosarcoma, a highly aggressive tumour of deep soft tissue mimicking metastatic carcinoma and co-expressing endothelial and epithelial markers.
authors.affiliation: Institute of Pathology, Queen Elizabeth Hospital, Hong Kong.
authors.forename: W Y
authors.initials: WY
authors.lastname: Tsang
authors.forename: J K
authors.initials: JK
authors.lastname: Chan
authors.forename: C D
authors.initials: CD
authors.lastname: Fletcher
mesh_terms: D003937:Diagnosis, Differential; D006390:Hemangioendothelioma / Q000175:diagnosis / Q000473:pathology; D006391:Hemangioma / Q000175:diagnosis / Q000473:pathology; D006394:Hemangiosarcoma / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008202:Lymphangioma / Q000175:diagnosis / Q000473:pathology; D009383:Neoplasms, Vascular Tissue / Q000175:diagnosis / Q000473:pathology*; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000473:pathology*