[Radiology of thalassemic syndrome in the transition from the old to the new therapeutic transfusion regimen].
The authors have evaluated the skull, thorax, wrist and hand standard radiographs of 29 patients affected by Cooley's disease who were treated up to 1983 with a low transfusion regimen, rather with a high transfusion regimen (Hb level greater than 9.5 g/dl). The patients have been divided into two groups, according to the prevalence of the first or the second transfusion regimen. Almost all the changes described in the literature have been found in the radiographs, but completely modified; some of these, like rib notchings, in higher percentage than known. In the youngest patients the most significant appearances were ribs and hand changes, that can be considered the most important feature in their radiological monitoring. However this new transitional radiological syndrome will rapidly modify with the establishment "ab initio" of the high transfusional regimen.
De Luca
B
B
Istituto di Radiologia, Università di Catania, Italia.
Magnano
C
C
Caruso
V
V
Blandini
S
S
Massimino
R
R
Majorana
M
M
D000293:Adolescent; D000328:Adult; D001803:Blood Transfusion / Q000379:methods*; D002648:Child; D005260:Female; D006225:Hand / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D013902:Radiography, Thoracic; D012886:Skull / Q000000981:diagnostic imaging; D013577:Syndrome; D013789:Thalassemia / Q000000981:diagnostic imaging* / Q000628:therapy*; D014953:Wrist / Q000000981:diagnostic imaging
La sindrome radiologica talassemica di transizione fra vecchio e nuovo regime terapeutico trasfusionale.