[Use of alpha interferon preparations in acute lymphoblastic leukemia in children during remission].
The Soviet alpha-interferon drugs (human leukocytic interferon, reaferon) were used in the program of the treatment of children with acute lymphoblastic leukemia (during remission). The treatment was found to be more effective with an increase of its duration, relapse-free course of the disease (69.4-82.3%) and survival (70.1-93.1%) of patients with an unfavourable disease prognosis (over 5 years).
Gavrilova
I E
IE
Kuznetsov
I P
IP
Denisov
L A
LA
Maiakova
S A
SA
Orlova
T G
TG
Kadagidze
Z G
ZG
Makhonova
L A
LA
D000293:Adolescent; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007370:Interferon Type I / Q000627:therapeutic use*; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000401:mortality / Q000628:therapy*; D011379:Prognosis; D011994:Recombinant Proteins; D012074:Remission Induction
D000970:Antineoplastic Agents; D007370:Interferon Type I; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins
Primenenie preparatov alfa-interferona pri ostrom limfoblastnom leĭkoze u deteĭ v periode remissii.