Thermal and mechanical responses of the amphibian skin to nerve stimulation.
The isolated calf skin of the toad and bullfrog was found to generate a burst of heat in response to stimulation of the cutaneous nerve. The electric responses of the skin evoked by nerve stimulation invariably lagged behind the heat burst. The generation of a heat burst was followed by a slow mechanical response of the skin. Suppression of these responses by adrenergic blocking agents suggests that heat is produced at the junction between the gland cells and the sympathetic nerve fibers. Large mechanical changes in the skin were observed when noradrenaline was applied to the inner surface of the skin.
Tasaki
I
I
Unit on Neurobiology, National Institute of Mental Health, Bethesda, Maryland 20892.
Byrne
P M
PM
D000818:Animals; D001696:Biomechanical Phenomena; D001833:Body Temperature Regulation / Q000502:physiology*; D002024:Bufo marinus; D004558:Electric Stimulation; D066298:In Vitro Techniques; D009638:Norepinephrine / Q000494:pharmacology; D011892:Rana catesbeiana; D012867:Skin / Q000187:drug effects / Q000294:innervation*; D012879:Skin Physiological Phenomena; D012881:Skin Temperature / Q000502:physiology; D013565:Sympatholytics / Q000494:pharmacology
D013565:Sympatholytics; D009638:Norepinephrine