[Effect of isoflurane on muscle relaxation in a patient with myotonic dystrophy].
We did anesthetic management by isoflurane for total thyroidectomy under the neuromuscular transmission monitoring in a patient with myotonic dystrophy. In three patients without neuromuscular disorders, T1 was 85% of control and fade was not observed, while in this case T1 was 40% of the control and TOFR was decreased to 50%. We conclude that isoflurane has a good muscle relaxation effect in this disease and, we could manage without administering any muscle relaxants.
Komatsu
H
H
Department of Anesthesiology, Akita University School of Medicine.
Horiguchi
T
T
Enzan
K
K
Satoh
W
W
Shouji
K
K
Suzuki
M
M
D000328:Adult; D000769:Anesthesia, Inhalation; D005260:Female; D006801:Humans; D007530:Isoflurane / Q000494:pharmacology*; D009126:Muscle Relaxation / Q000187:drug effects*; D009223:Myotonic Dystrophy / Q000150:complications*; D013965:Thyroidectomy
D007530:Isoflurane