title: [Automated information-diagnostic system for hereditary diseases in childhood].
abstract: This article describes computer-based information-and-diagnostic system dealing with child hereditary diseases which makes in possible to organize automated consultative service on a wide range of monogene and chromosome syndromes. The system is oriented for sorting out a narrow differential-and-diagnostic row from 1200 of genetically determined diseases at the stage of pre-laboratory child examination. The choice of diagnoses in the system is based on the analysis of the likeness of phenotypical manifestation of the syndromes described in literature with the case under analysis. The system envisages information exchange with a physician in a dialogue using the natural language. The system is based on IBM-370 computer and can be operated from remote video device in the data TV transmitting mode.
authors.forename: B A
authors.initials: BA
authors.lastname: Kobrinskiĭ
authors.forename: L Z
authors.initials: LZ
authors.lastname: Kazantseva
authors.forename: A E
authors.initials: AE
authors.lastname: Gel'dman
authors.forename: E A
authors.initials: EA
authors.lastname: Nikolaeva
authors.forename: P V
authors.initials: PV
authors.lastname: Novikov
authors.forename: A N
authors.initials: AN
authors.lastname: Semiachkina
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Chebeliaev
authors.forename: S B
authors.initials: SB
authors.lastname: Kudriavskaia
authors.forename: T P
authors.initials: TP
authors.lastname: Zhuravleva
authors.forename: Iu E
authors.initials: IuE
authors.lastname: Vel'tishchev
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D005103:Expert Systems; D030342:Genetic Diseases, Inborn / Q000175:diagnosis*; D006801:Humans; D010641:Phenotype
vernacular_title: Avtomatizirovannaia informatsionno-diagnosticheskaia sistema po nasledstvennym zabolevaniiam v detskom vozraste.