[Comparison of solid phase and liquid-liquid extraction of diazepam and nitrazepam].
We have developed a new extraction technique for nitrazepam and diazepam using Samplex C-18 column. The blood-extractions containing diazepam and nitrazepam were diluted with acetonitrile-water 7:3 eluent. Diazepam and nitrazepam were isolated using liquid-liquid extraction technique. The blood-extracts were diluted with chloroform-ethanol 1:1 and they were evaluated by using OPLC method. Evaluation was done by TLC-scanner (Shimadzu). The efficiency and sensitivity of the methods have been compared.
Gaál Szabó
Z
Z
Országos Igazságügyi Toxikológiai Intézet, Budapest.
Perneczki
S
S
D002845:Chromatography / Q000379:methods*; D003975:Diazepam / Q000302:isolation & purification*; D009567:Nitrazepam / Q000302:isolation & purification*
D009567:Nitrazepam; D003975:Diazepam
Diazepam és nitrazepam szilárd fázisú és folyadék-folyadék extrakciójának összehasonlítása.