Cutaneous response to ultraviolet radiation-induced erythema in patients with type A dysplastic nevi.
The effects of an exposure to 6 times the minimal erythemal dose of ultraviolet radiation (UV) were studied using a visual scale and a tri-stimulus colorimeter in 12 sun-tolerant (skin types III and IV) patients with type A dysplastic nevus syndrome. In such individuals, the melanocytic system would be susceptible to neoplastic transformation induced by sunlight. The cutaneous response to a marked UVB erythema has been shown to identify the high-risk patients prone to light-induced skin cancer. This study indicates that the UVB cutaneous susceptibility of patients with type A dysplastic nevi is not significantly different from control subjects, in terms of erythemal and tanning response.
Aubin
F
F
Service de Dermatologie I, Hôpital St-Jacques, Besançon, France.
Manteaux
A
A
Zultak
M
M
Agache
P
P
D000328:Adult; D003116:Color; D003124:Colorimetry / Q000379:methods; D004198:Disease Susceptibility; D004416:Dysplastic Nevus Syndrome / Q000145:classification / Q000503:physiopathology*; D004890:Erythema / Q000473:pathology / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000503:physiopathology; D012867:Skin / Q000473:pathology / Q000528:radiation effects*; D012878:Skin Neoplasms / Q000503:physiopathology*; D012880:Skin Pigmentation / Q000528:radiation effects*; D014466:Ultraviolet Rays