Progesterone receptor expression in human cervix uteri.
Progesterone receptor (PR) expression was studied in human cervix uteri from 21 cases. The study was performed on fresh frozen material with application of mouse anti-rabbit PR antibody and the immunoperoxidase method. Most cervical PR-s were present in the glandular epithelium and in smooth muscle cells. The results suggest that PR expression in the cervical glands is hormone-dependent; it was strongest in the presence of estrogen-stimulated endometrium, weaker with progesterone stimulation and absent in atrophy. The ectocervical epithelium contained relatively few progesterone receptors.
Kupryjańczyk
J
J
Department of Pathomorphology, Institute of Obstetrics and Gynecology, Medical School of Warsaw, Poland.
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002584:Cervix Uteri / Q000737:chemistry*; D004848:Epithelium / Q000737:chemistry; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008593:Menopause; D008875:Middle Aged; D009130:Muscle, Smooth / Q000737:chemistry; D011980:Receptors, Progesterone / Q000032:analysis*
D011980:Receptors, Progesterone