Heat shock proteins in immunopathology.
In recent years, studies have suggested that autoimmunity and/or immunopathology may sometimes result from the immune response to heat shock proteins of autologous cells and microorganisms. Focusing on the T-cell mediated responses, we review the latest literature on this issue with regard to three hypothetical concepts of immunopathology in which heat shock proteins might play a role.
Res
P C
PC
University Hospital, Leiden, The Netherlands.
Thole
J E
JE
de Vries
R R
RR
D001327:Autoimmune Diseases / Q000276:immunology*; D003429:Cross Reactions; D006360:Heat-Shock Proteins / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*
D006360:Heat-Shock Proteins