The in vitro activity of flomoxef compared to four other cephalosporins and imipenem.
The antibacterial activity of the oxacephalosporin flomoxef was evaluated in comparison to cefpirome, cefuzoname, cefotaxime, ceftazidime, and imipenem against fresh clinical isolates. Flomoxef is an antibiotic with strong antibacterial activity against staphylococci including methicillin-resistant strains and streptococci with the exception of Enterococcus faecalis and Enterococcus faecium. It is very active against gram-negative cocci and rods including gram-positive and gram-negative anaerobes. Against Pseudomonas sp. flomoxef has no activity.
Shah
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PM
Klinikum der Johann Wolfgang Goethe-Universität, Frankfurt am Main, Germany.
Knothe
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H
D002511:Cephalosporins / Q000494:pharmacology*; D015378:Imipenem / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests
D002511:Cephalosporins; D015378:Imipenem; C045693:flomoxef