[Comparative characteristics of the effectiveness of oxygen delivery to the tissues by human erythrocytes preserved with glugicir and citroglucophosphate].
The main parameters of hemodynamics and oxygen regimen were investigated in isolated rat heart (130 tests) during its perfusion with red blood cells preserved in glugicir (GGC) and citroglucophosphate (CGP). Short-term storage red blood cells did not show disorders in O2 transport to tissues. Long-term storage red blood cells (both in GGC and CGP) showed disorders in hemodynamics that were associated with appearance of free hemoglobin in the perfusion medium due to disruption of some red blood cells by the perfusion apparatus.
Iarochkin
V S
VS
Koziner
V B
VB
Agranenko
V A
VA
Tibilova
N N
NN
Golubeva
V L
VL
D000818:Animals; D000925:Anticoagulants / Q000494:pharmacology; D001793:Blood Preservation; D002951:Citrates / Q000494:pharmacology; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism*; D005947:Glucose / Q000494:pharmacology; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D066298:In Vitro Techniques; D008955:Models, Cardiovascular; D009206:Myocardium / Q000378:metabolism*; D010101:Oxygen Consumption / Q000502:physiology*; D010477:Perfusion; D051381:Rats
D000925:Anticoagulants; D002951:Citrates; C007077:citrate phosphate dextrose; D005947:Glucose
Sravnitel'naia kharakteristika éffektivnosti otdachi kisloroda tkaniam éritrotsitami cheloveka, konservirovannymi na gliugitsire i tsitrogliukofosfate.