Effect of a diet rich in linseed oil on complex viscosity and blood pressure in spontaneously hypertensive rats (SHR).
The influence of a diet rich in linseed oil (10% in weight) with a content of 61.2% of alpha-linolenic fatty acid on blood pressure and complex blood viscosity was investigated in spontaneously hypertensive rats. A decrease in blood pressure by 59 mm Hg was found compared to the age-matched, untreated control group. The viscous (eta') and elastic (eta") components of viscosity were also reduced at various shear rates (gamma). The same applies to the aggregation index, which is a measure of the aggregation tendency of red blood cells (RBC). Of course, the effects on blood viscosity cannot explain the observed degree of blood-pressure-lowering. Nevertheless, a decrease in the viscosity can improve the flow conditions in the microcirculation, which may lead to a better oxygen supply.
Dierberger
B
B
Physiologisches Institut II, Universität Tübingen.
Schäch
M
M
Anadere
I
I
Brändle
M
M
Jacob
R
R
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D001809:Blood Viscosity / Q000187:drug effects*; D002449:Cell Aggregation; D004042:Dietary Fats, Unsaturated / Q000494:pharmacology*; D004912:Erythrocytes / Q000502:physiology; D008043:Linseed Oil / Q000494:pharmacology*; D008297:Male; D051381:Rats; D011918:Rats, Inbred SHR / Q000097:blood / Q000502:physiology*
D004042:Dietary Fats, Unsaturated; D008043:Linseed Oil