title: Determination of levamisole and thiabendazole in meat by HPLC and photodiode array detection.
abstract: An HPLC method for the analysis of levamisole and thiabendazole has been developed with recoveries varying over 63-75%. The two anthelmintics are extracted from meat with ethyl acetate, purified by liquid/liquid extraction and analyzed quantitatively on a mu Bondapak C18 column. The optimum detection is achieved by means of a photodiode array detector at 240 nm for levamisole and at 300 nm for thiabendazole. The detection limits for both compounds in meat are 25 micrograms/kg and 5 micrograms/kg, respectively.
authors.affiliation: Ministère de la Santé Publique et de l'Environnement, Bruxelles, Belgium.
authors.forename: B
authors.initials: B
authors.lastname: Wyhowski de Bukanski
authors.forename: J M
authors.initials: JM
authors.lastname: Degroodt
authors.forename: H
authors.initials: H
authors.lastname: Beernaert
mesh_terms: D000818:Animals; D002851:Chromatography, High Pressure Liquid; D004350:Drug Residues / Q000032:analysis*; D007978:Levamisole / Q000032:analysis*; D008460:Meat / Q000032:analysis*; D015203:Reproducibility of Results; D013827:Thiabendazole / Q000032:analysis*
chemical_list: D007978:Levamisole; D013827:Thiabendazole