title: Reliability of evoked responses to high-frequency (8-14 kHz) tone bursts.
abstract: Instrumentation to evaluate the auditory brainstem response to high-frequency (8-14 kHz) tone bursts has been developed in the Auditory Research Laboratory, Portland, Oregon VA Medical Center. This system is intended to monitor the audition of patients receiving ototoxic drugs who are unresponsive to behavioral test procedures. The reliability of responses obtained with the high-frequency tone-burst system was studied in 30 normal ears. Intrasubject variability of intersession data from response waves I, III, and V to tone bursts of frequencies 8, 10, 12, and 14 kHz was not significantly different from click response variability. The results of this study demonstrate the reliability of the ABR to these high-frequency tone-burst stimuli. This technique may provide early identification of hearing loss in unresponsive subjects receiving treatment with potentially ototoxic agents, thus allowing alternative treatments to minimize or prevent communicative handicap.
authors.affiliation: Portland Veterans Affairs Medical Center (PVAMC), OR 97207.
authors.forename: S A
authors.initials: SA
authors.lastname: Fausti
authors.forename: B Z
authors.initials: BZ
authors.lastname: Rappaport
authors.forename: R H
authors.initials: RH
authors.lastname: Frey
authors.forename: J A
authors.initials: JA
authors.lastname: Henry
authors.forename: D S
authors.initials: DS
authors.lastname: Phillips
authors.forename: C R
authors.initials: CR
authors.lastname: Mitchell
authors.forename: D J
authors.initials: DJ
authors.lastname: Olson
mesh_terms: D000161:Acoustic Stimulation; D000162:Acoustics; D000328:Adult; D000617:Aminoglycosides / Q000009:adverse effects; D000704:Analysis of Variance; D001300:Audiometry, Evoked Response / Q000295:instrumentation* / Q000379:methods; D016057:Evoked Potentials, Auditory, Brain Stem / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D011930:Reaction Time; D015203:Reproducibility of Results
chemical_list: D000617:Aminoglycosides