title: Primary intraosseous squamous carcinoma. Report of two cases.
abstract: Two cases of primary intraosseous squamous carcinoma (PIOSC) are reported. One PIOSC is in the mandible of a 24-year-old man and appears to be a keratinizing PIOSC arising de novo. The other PIOSC presented in the edentulous maxilla of a 56-year-old man and was diagnosed as a PIOSC arising from an odontogenic cyst. The 2nd tumor subsequently metastasized to a cervical lymph node. Previous reports have noted a favorable prognosis for PIOC arising in odontogenic cysts, and only 3 other instances of metastases of a PIOSC in an odontogenic cyst have been documented.
authors.affiliation: Department of Oral Pathology, Emory University, Atlanta, Georgia.
authors.forename: S
authors.initials: S
authors.lastname: Müller
authors.forename: C A
authors.initials: CA
authors.lastname: Waldron
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000556:secondary; D006258:Head and Neck Neoplasms / Q000556:secondary; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology; D008439:Maxillary Diseases / Q000473:pathology; D008441:Maxillary Neoplasms / Q000473:pathology; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009807:Odontogenic Cysts / Q000473:pathology; D009808:Odontogenic Tumors / Q000473:pathology / Q000556:secondary