[Level of plasma fibronectin and its biological activity in patients with ovarian cancer].
Plasma level of fibronectin and its biological activity were assessed in 33 females suffering ovarian cancer; 13 cases had stage I or II disease whereas 20-stage III or IV tumors. Fibronectin level, as measured by immunoelectrophoresis, proved normal. This was accompanied by a statistically significant (p less than 0.05) rise in gelatin--binding activity of the glycoprotein in patients with stage I-II cancer which accounted for an increased value registered for the entire group studied. However, no such rise was observed in cases of stage III and IV disease.
Kharrasov
A F
AF
Safina
N A
NA
Moroz
I P
IP
Zinkevich
O F
OF
D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor; D005260:Female; D005353:Fibronectins / Q000097:blood* / Q000378:metabolism; D006801:Humans; D007122:Immunoelectrophoresis; D008875:Middle Aged; D009391:Nephelometry and Turbidimetry; D010051:Ovarian Neoplasms / Q000097:blood* / Q000175:diagnosis / Q000473:pathology; D011485:Protein Binding
D014408:Biomarkers, Tumor; D005353:Fibronectins
Uroven' plazmennogo fibronektina i ego biologicheskaia aktivnost' u bol'nykh rakom iaichnikov.