title: Genetic variation in resistance of turkeys to experimental challenge with Pasteurella multocida.
abstract: Six hundred fifty-five male and female turkeys representing four genetic lines were challenged in 10 experiments over a 3-year period with a field isolate of Pasteurella multocida. Poults were challenged at 45 days of age with 1 ml of an inoculum containing 1.2 x 10(7) bacteria per ml. The lines of turkeys included two randombred control lines (RBC1 and RBC2), a subline (E) of RBC1 selected for increased egg production, and a subline (F) of RBC2 selected for increased 16-week body weight. The number of days from exposure to severe clinical signs or death for Line F (5.8 days) differed significantly from that of Line E (8.2 days), Line RBC1 (8.0 days), and Line RBC2 (8.2 days). There were no significant differences due to sex of poult for number of days from exposure to severe clinical signs or death. Overall mortality observed was 51.2%. Mortality was highest for Line F (72.1%) and differed significantly from that of the other lines. Mortality among male poults did not differ significantly from mortality among female poults.
authors.affiliation: Department of Poultry Science, Ohio State University, Wooster 44691.
authors.forename: R E
authors.initials: RE
authors.lastname: Sacco
authors.forename: Y M
authors.initials: YM
authors.lastname: Saif
authors.forename: K E
authors.initials: KE
authors.lastname: Nestor
authors.forename: N B
authors.initials: NB
authors.lastname: Anthony
authors.forename: D A
authors.initials: DA
authors.lastname: Emmerson
authors.forename: R N
authors.initials: RN
authors.lastname: Dearth
mesh_terms: D000818:Animals; D001835:Body Weight / Q000235:genetics; D005260:Female; D014644:Genetic Variation; D007113:Immunity, Innate / Q000235:genetics; D008297:Male; D010058:Oviposition / Q000235:genetics; D010326:Pasteurella Infections / Q000235:genetics / Q000276:immunology / Q000401:mortality / Q000662:veterinary*; D016979:Pasteurella multocida / Q000276:immunology*; D011201:Poultry Diseases / Q000235:genetics* / Q000276:immunology / Q000401:mortality; D014422:Turkeys