title: Correlates of high-density lipoprotein cholesterol in a sample of healthy workers.
abstract: METHODS
  Correlates of high-density lipoprotein cholesterol are analyzed in a sample of 797 male workers in southern Italy participating in the Olivetti Heart Study. At the univariate level high-density lipoprotein cholesterol concentrations are positively related to alcohol consumption (r = 0.127; P less than or equal to 0.001) and sport activity (r = 0.074; P less than or equal to 0.05) and inversely related to body mass index (r = -0.160; P less than or equal to 0.001), serum triglycerides (r = -0.349; P less than or equal to 0.001), cigarette smoking (r = -0.227; P less than or equal to 0.001), and coffee consumption (r = -0.153; P less than or equal to 0.001).
  
  
  RESULTS
  In the group as a whole, body mass index, alcohol consumption, cigarette smoking, and serum triglycerides remain significantly related to high-density lipoprotein cholesterol in the multivariate model, while the association with coffee intake and sport activity loses statistical significance. A significant negative interaction is reported between physical activity and cigarette smoking, and a positive significant linear trend between high-density lipoprotein cholesterol and sport activity is observed only in nonsmokers.
  
  
  CONCLUSIONS
  These findings suggest that body mass index, alcohol consumption, cigarette smoking, serum triglycerides, and sport activity are important correlates of high-density lipoprotein cholesterol but that the positive significant association between sport activity and high-density lipoprotein cholesterol is absent in smokers.
authors.affiliation: Department of Social and Preventive Medicine, State University of New York, Buffalo 14214.
authors.forename: F
authors.initials: F
authors.lastname: Jossa
authors.forename: M
authors.initials: M
authors.lastname: Trevisan
authors.forename: V
authors.initials: V
authors.lastname: Krogh
authors.forename: E
authors.initials: E
authors.lastname: Farinaro
authors.forename: D
authors.initials: D
authors.lastname: Giumetti
authors.forename: G
authors.initials: G
authors.lastname: Fusco
authors.forename: R
authors.initials: R
authors.lastname: Galasso
authors.forename: S
authors.initials: S
authors.lastname: Frascatore
authors.forename: C
authors.initials: C
authors.lastname: Mellone
authors.forename: M
authors.initials: M
authors.lastname: Mancini
mesh_terms: D000328:Adult; D000368:Aged; D000428:Alcohol Drinking / Q000009:adverse effects; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood*; D003069:Coffee / Q000009:adverse effects; D015444:Exercise; D006801:Humans; D006951:Hyperlipoproteinemias / Q000097:blood / Q000453:epidemiology* / Q000209:etiology; D007558:Italy / Q000453:epidemiology; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D013177:Sports; D014280:Triglycerides / Q000097:blood
chemical_list: D008076:Cholesterol, HDL; D003069:Coffee; D014280:Triglycerides; D002784:Cholesterol