title: Case report 700: Primary intracortical osteosarcoma of femur, sclerosing variant, grade 1 to 2 anaplasia.
abstract: We report a case of intracortical OS of the mid-femur in a 43-year-old man. The patient is the oldest reported to date. Histologically, the tumor was a sclerosing variant of OS with extensive "normalization" of nuclei. This is the most common histological subtype of intracortical OS. The patient was treated by en bloc resection without preoperative or systemic chemotherapy and is without evidence of disease with 15 months' follow-up.
authors.affiliation: Department of Pathology, UCLA Medical Center.
authors.forename: J M
authors.initials: JM
authors.lastname: Mirra
authors.forename: L
authors.initials: L
authors.lastname: Dodd
authors.forename: W
authors.initials: W
authors.lastname: Johnston
authors.forename: D B
authors.initials: DB
authors.lastname: Frost
authors.forename: D
authors.initials: D
authors.lastname: Barton
mesh_terms: D000328:Adult; D000708:Anaplasia; D003937:Diagnosis, Differential; D005266:Femoral Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D005269:Femur / Q000473:pathology*; D006801:Humans; D008297:Male; D012516:Osteosarcoma / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery