Interstrain differences in organization of metabolic processes in the rat liver--I. The dynamics of changes in the contents of adenine nucleotides, glycogen and fatty acyl-CoAs in the course of short-term starvation in the livers of rats of Wistar, August and WAG strains.
1. The metabolic patterns in the livers of rats of the Wistar, August and Wag strains were evaluated 4, 8, 12 and 24 hr after food withdrawal. 2. In the fed state (4 hr) there were large differences in the liver's contents of ATP, phosphate potential values, glycogen contents and blood FFA. These distinctions disappeared in the fasted state (12 hr). 3. There are large differences between the strains in the dynamics of transition of the liver metabolic patterns from the fed to the starved states. 4. The results obtained show that the three strains of the laboratory animals strongly differ in the organization of the liver energy metabolism.
Panov
A
A
Laboratory of Bioenergetics, Academy of Medical Sciences of U.S.S.R., Siberian Branch, Novosibirsk.
Solovyov
V
V
Vavilin
V
V
D000214:Acyl Coenzyme A / Q000378:metabolism*; D000227:Adenine Nucleotides / Q000378:metabolism*; D000818:Animals; D006003:Glycogen / Q000378:metabolism*; D007700:Kinetics; D008099:Liver / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013045:Species Specificity; D013217:Starvation / Q000378:metabolism*
D000214:Acyl Coenzyme A; D000227:Adenine Nucleotides; D006003:Glycogen