title: [Shape changes in contrast VEP in multiple sclerosis: relation to the type of lesion].
abstract: VEP changes in MS patients are due to the demyelinating process which causes conduction alterations as well as inhibitory mechanisms. The pattern-shift VEP can show a delay of the main positivity, a diminished amplitude or/and an altered shape and duration. Concerning to series from the literature and own observations on more than 500 MS patients 4 different types of VEP alterations can be observed: 1. NPN complex with P2 delay; 2. broadening with loss of N2 and P2 delay; 3. bifid P2, P100-P135 complex; 4. deformation and dissociation with loss of P2, N105 dominance and amplitude reduction.
authors.affiliation: Neurologische Klinik des Klinikums Ludwigshafen.
authors.forename: K
authors.initials: K
authors.lastname: Lowitzsch
mesh_terms: D005074:Evoked Potentials, Visual / Q000502:physiology*; D006801:Humans; D009103:Multiple Sclerosis / Q000503:physiopathology*; D010364:Pattern Recognition, Visual / Q000502:physiology*
vernacular_title: Formveränderungen des Kontrast-VEP bei multipler Sklerose: Beziehung zum Läsionstyp.