Morphometric comparison of uterine glandular epithelium in the early secretory phase from patients treated with different superovulatory drugs on an in vitro fertilization programme.
The glandular structure in the uterine epithelium of three groups of patients on standard superovulatory regimes was studied using a fully automated image analysis system. It was found that one treatment (buserelin stimulation) produced more glandular area than either of the other two. We suggest that buserelin gives the morphometric appearance of the most normal endometrial glands and find that our morphometric analysis is a reliable means to evaluate glandular structure in patients on superovulatory therapy.
Hosie
M J
MJ
Department of Histology and Embryology, University of Sydney, N.S.W., Australia.
Murphy
C R
CR
Rogers
P A
PA
Dwarte
D M
DM
D002064:Buserelin / Q000494:pharmacology*; D002996:Clomiphene / Q000494:pharmacology*; D004338:Drug Combinations; D004717:Endometrium / Q000187:drug effects*; D005260:Female; D005307:Fertilization in Vitro / Q000187:drug effects*; D006801:Humans; D008596:Menotropins / Q000494:pharmacology*; D010062:Ovulation Induction; D014599:Uterus / Q000033:anatomy & histology / Q000187:drug effects*
D004338:Drug Combinations; D002996:Clomiphene; D008596:Menotropins; D002064:Buserelin