title: [Localized primary cutaneous nodular amyloidosis].
abstract: A case of cutaneous nodular amyloidosis in a 60-year-old man is described with reference to histological, immunohistochemical and ultrastructural features. Clinically, the patient presented two brownish nodules on his face. Histologically, a massive dermal collection of eosinophilic, homogeneous material showing positivity for Congo red stain was revealed. Immunoreactivity for both Ig-light chains was detected in dermal plasma cells as well as in amyloid material. Ultramicroscopically, the typical fibrillary pattern of amyloid was found. Clinical and instrumental examinations failed to demonstrate amyloid depositions elsewhere in the body.
authors.affiliation: Divisioni di Anatomia Patologica, P.O.M., G. Rummo di Benevento.
authors.forename: G
authors.initials: G
authors.lastname: Ferrara
authors.forename: F
authors.initials: F
authors.lastname: Cusano
authors.forename: M
authors.initials: M
authors.lastname: Capozzi
authors.forename: G
authors.initials: G
authors.lastname: De Dominicis
mesh_terms: D000682:Amyloid / Q000032:analysis; D000686:Amyloidosis / Q000175:diagnosis / Q000473:pathology*; D003224:Congo Red; D005148:Facial Dermatoses / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D007147:Immunoglobulin Light Chains / Q000032:analysis; D008297:Male; D008875:Middle Aged
chemical_list: D000682:Amyloid; D007147:Immunoglobulin Light Chains; D003224:Congo Red
vernacular_title: Amiloidosi nodulare cutanea primaria localizzata.