[The comparative efficacy and prognosis of the long-term treatment with korinfar of men and women suffering from hypertension].
The paper is concerned with the results of the corinfar treatment for a year of men and women suffering from stage II stable essential hypertension. The treatment efficacy, the influence on central hemodynamics were estimated as was the prognostic significance of different variants of acute pharmacological tests (sublingual, oral, oral with the use of static loading) compared with the treatment results. The long-term monotherapy with corinfar was shown to be effective in the majority of patients suffering from stage II stable essential hypertension. However, in women with essential hypertension, the hypotensive effect was more stable, the effective doses were lower, and tolerance was better than in men. To predict the efficacy of the long-term monotherapy a method of acute pharmacological test with the use of static leading devised by the authors is suggested. The method has a high prognostic significance.
Maslova
N P
NP
Baranova
E I
EI
Barabanova
N G
NG
D000328:Adult; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D002908:Chronic Disease; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000627:therapeutic use*; D011379:Prognosis; D012727:Sex Characteristics; D013997:Time Factors
D002121:Calcium Channel Blockers; D009543:Nifedipine
Sravnitel'naia éffektivnost' i prognoz dlitel'nogo lecheniia korinfarom muzhchin i zhenshchin, stradaiushchikh gipertonicheskoĭ bolezn'iu.