title: Crystallographic refinement of bovine pro-phospholipase A2 at 1.6 A resolution.
abstract: Bovine pro-phospholipase A2 (Mr = 14,520), trigonal, P3(1)21, a = b = 46.5, c = 102.0 A, one molecule per asymmetric unit, lambda (Cu K alpha) = 1.54 A. The model incorporating 895 protein atoms, two molecules of 2-methyl-2,4-pentanediol, and 60 solvent water molecules, was refined by restrained least squares to a residual R = 0.194 for 14,667 reflections from 5 to 1.6 A resolution.
authors.affiliation: DuPont Merck Pharmaceutical Company, Wilmington, DE 19880-0228.
authors.forename: B C
authors.initials: BC
authors.lastname: Finzel
authors.forename: P C
authors.initials: PC
authors.lastname: Weber
authors.forename: D H
authors.initials: DH
authors.lastname: Ohlendorf
authors.forename: F R
authors.initials: FR
authors.lastname: Salemme
mesh_terms: D004792:Enzyme Precursors / Q000737:chemistry*; D010741:Phospholipases A / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: D004792:Enzyme Precursors; D010741:Phospholipases A