[The immunobiological effects of nitrogranulogen. I. Summarizing the results of the immunological studies to date].
It has been shown that nitrogranulogen is a strong inhibitor of human T and B lymphoproliferation, antibody synthesis in vitro and in vivo as well as natural killer (NK) activity. The drug enhances IL 1 secretion, but blocks its cellular interactions.
Górski
A
A
Zakładu Immunologii Instytutu Transplantologii AM, Warszawie.
Wasik
M
M
Nowaczyk
M
M
Stepień-Sopniewska
B
B
D000818:Animals; D001402:B-Lymphocytes / Q000166:cytology / Q000187:drug effects* / Q000276:immunology; D002455:Cell Division / Q000187:drug effects / Q000502:physiology; D006681:HLA-D Antigens / Q000096:biosynthesis / Q000276:immunology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D066298:In Vitro Techniques; D007375:Interleukin-1 / Q000096:biosynthesis / Q000276:immunology*; D008466:Mechlorethamine / Q000494:pharmacology*; D051379:Mice; D008954:Models, Biological; D013601:T-Lymphocytes / Q000166:cytology / Q000187:drug effects* / Q000276:immunology
D006681:HLA-D Antigens; D007166:Immunosuppressive Agents; D007375:Interleukin-1; D008466:Mechlorethamine
Badania nad immunobiologicznym działaniem nitrogranulogenu. Cześć I. Podsumowanie wyników dotychczasowych badań immunologicznych.