Relative sensitivity of myeloid and lymphatic stem cells to mutational and cell killing effects of ionizing radiation.
Following exposure to a high dose of ionizing radiation there is a much greater risk of developing myeloid than lymphatic leukaemia. Reasons are given why this difference probably owes more to cell killing than mutational effects of the radiation.
Stewart
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Department of Social Medicine, University of Birmingham, Edgbaston, U.K.
D016923:Cell Death / Q000528:radiation effects; D006412:Hematopoietic Stem Cells / Q000473:pathology / Q000528:radiation effects; D006801:Humans; D007945:Leukemia, Lymphoid / Q000235:genetics / Q000473:pathology*; D007951:Leukemia, Myeloid / Q000235:genetics / Q000473:pathology*; D007953:Leukemia, Radiation-Induced / Q000235:genetics / Q000473:pathology*; D009154:Mutation / Q000528:radiation effects*; D014411:Neoplastic Stem Cells / Q000473:pathology / Q000528:radiation effects