[Activity, hexokinase isoenzyme spectrum and various factors of their regulation in liver and skeletal muscles of young piglets].
Hexokinase in the liver of 1- and 5-day-old piglets is presented by four isoforms and in the skeletal muscles--by two ones. The enzyme activity in the liver and skeletal muscles of 5-day-old piglets is much higher than in 1-day-old ones. The increased hexokinase activity in the tissues of piglets during the first days of life appears to be due to the changes in their isoenzyme spectrum. The hexokinase activity and isoenzyme spectrum in the investigated tissue were affected by insulin, cortisol and 24 hours long starvation. These changes depended upon the age of the animals and differed in various organs and tissues: in 1-day-old piglets they were more pronounced in the skeletal muscles, while in 5-days-old animals--in the liver.
Galias
G M
GM
Sintinskiĭ
V V
VV
Ianovich
V G
VG
D000375:Aging / Q000378:metabolism*; D000818:Animals; D000831:Animals, Newborn / Q000378:metabolism*; D006593:Hexokinase / Q000187:drug effects / Q000378:metabolism*; D006854:Hydrocortisone / Q000494:pharmacology; D007328:Insulin / Q000494:pharmacology; D007527:Isoenzymes / Q000187:drug effects / Q000378:metabolism*; D008099:Liver / Q000201:enzymology*; D009132:Muscles / Q000201:enzymology*; D009928:Organ Specificity / Q000502:physiology; D013217:Starvation / Q000503:physiopathology; D013552:Swine
D007328:Insulin; D007527:Isoenzymes; D006593:Hexokinase; D006854:Hydrocortisone
Aktivnost', izofermentnyĭ spektr geksokinazy i nekotorye faktory ikh reguliatsii v pecheni i skeletnykh myshtsakh porosiat v rannem vozraste.