Regulation of autoimmunity.
Despite the prevalence of self-reactive T cells, the healthy organism is not in a state of all-out war. Potent regulatory mechanisms exist at every level to permit the successful integration of the various aspects of the immune system, allowing only minor skirmishes, which ordinarily can be neutralized.
Kumar
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V
University of California, Los Angeles.
Sercarz
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EE
D000818:Animals; D000941:Antigens / Q000276:immunology; D001327:Autoimmune Diseases / Q000276:immunology*; D015551:Autoimmunity / Q000276:immunology*; D001402:B-Lymphocytes / Q000276:immunology*; D007108:Immune Tolerance / Q000276:immunology*; D007130:Immunoglobulin Idiotypes / Q000276:immunology; D008285:Major Histocompatibility Complex / Q000276:immunology; D011948:Receptors, Antigen, T-Cell / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*
D000941:Antigens; D007130:Immunoglobulin Idiotypes; D011948:Receptors, Antigen, T-Cell