Study on rat-rat hybridoma technique and production of rat monoclonal antibodies against HIV and HBsAg.
The rat-rat hybridoma technique has some definite advantages in the three systems (mouse, rat or human system) currently utilized for monoclonal antibody production. The study on rat-rat hybridoma technique and its application to the productions of monoclonal antibodies against human immunodeficiency virus (HIV) and hepatitis B virus surface antigen (HBsAg) are described as examples in this paper.
Fang
J C
JC
Department of Cell Biology, Beijing Institute for Cancer Research, China.
Bodeus
M
M
Burtonboy
G
G
D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis* / Q000276:immunology / Q000302:isolation & purification; D002459:Cell Fusion; D002999:Clone Cells; D005260:Female; D006678:HIV / Q000276:immunology*; D006514:Hepatitis B Surface Antigens / Q000276:immunology*; D006825:Hybridomas; D007114:Immunization; D008297:Male; D051381:Rats
D000911:Antibodies, Monoclonal; D006514:Hepatitis B Surface Antigens