Phylogeny and molecular epidemiology of Sporothrix schenckii in Japan.
Mitochondrial DNA(mtDNA) diversity was investigated in 257 clinical isolants of Sporothrix schenckii obtained from 4 districts in Japan. S. schenckii was classified into 10 types based on Hae III restriction profiles. Phylogeny of types constructed by the method of Fitch and Margoliash [1] on the estimated sequence divergence within mtDNA using the methods of Nei and Li [2], showed that S. schenckii are grouped into 2 clusters, one group consisting of types 1, 2 and 3, and the other group consisting of the other seven types. In addition, types 1, 2, and 5 were correlated with their geographic origin, whereas type 4 was present throughout Japan.
Takeda
Y
Y
Department of Dermatology, Kanazawa Medical University, Ishikawa, Japan.
Kawasaki
M
M
Ishizaki
H
H
D004271:DNA, Fungal / Q000032:analysis*; D004272:DNA, Mitochondrial / Q000032:analysis*; D006801:Humans; D007564:Japan / Q000453:epidemiology; D010802:Phylogeny; D015183:Restriction Mapping; D013175:Sporothrix / Q000145:classification* / Q000235:genetics; D013174:Sporotrichosis / Q000453:epidemiology / Q000382:microbiology*
D004271:DNA, Fungal; D004272:DNA, Mitochondrial