Cerebellar interpositus nucleus lesions disrupt classical nictitating membrane conditioning but not discriminative avoidance learning in rabbits.
Cerebellar interpositus nucleus lesions were given to 14 rabbits trained in two behavioral paradigms; discriminative avoidance conditioning of locomotor behavior and classical nictitating membrane conditioning. Bilateral lesions that prevented acquisition of the classically conditioned response on both the left and right side failed to affect the acquisition or performance of the conditioned discriminative avoidance response. The results are discussed in terms of differences in neural substrates that apparently subserve the two forms of learning.
Steinmetz
J E
JE
Department of Psychology, Indiana University, Bloomington 47405.
Sears
L L
LL
Gabriel
M
M
Kubota
Y
Y
Poremba
A
A
Kang
E
E
D000818:Animals; D001245:Association Learning / Q000502:physiology; D001362:Avoidance Learning / Q000502:physiology*; D001931:Brain Mapping; D002529:Cerebellar Nuclei / Q000502:physiology*; D003214:Conditioning, Classical / Q000502:physiology*; D003215:Conditioning, Eyelid / Q000502:physiology*; D004193:Discrimination Learning / Q000502:physiology*; D011939:Mental Recall / Q000502:physiology*; D009043:Motor Activity / Q000502:physiology; D011817:Rabbits; D012153:Retention, Psychology / Q000502:physiology