The preparation of 2,4-dibromoestra-1,3,5(10),6-tetraene-3,17 beta-diol diacetate.
[2,4,6,7-3H4]Estradiol is used for the quantitative determination of estradiol receptors. The synthesis of 2,4-dibromoestra-1,3,5(10),6-tetraene-3,17 beta-diol 3,17-diacetate, the convenient precursor of [2,4,6,7-3H4]estradiol, is described. 6-Alkoxy compounds were also prepared and investigated.
Szendi
Z
Z
Department of Organic Chemistry, Attila József University, Szeged, Hungary.
Dombi
G
G
Vincze
I
I
D004958:Estradiol / Q000031:analogs & derivatives* / Q000138:chemical synthesis
C072602:2,4-dibromoestra-1,3,5(10),6-tetraene-3,17-diol diacetate; D004958:Estradiol