title: Bacterial vaginosis and the vaginal leucocyte/epithelial cell ratio in women attending an outpatient gynaecology clinic.
abstract: In order to investigate the usefulness of vaginal leucocytosis as a sign of genital infection, vaginal wet smears were obtained from 230 consecutive non-pregnant women attending an outpatient gynaecology clinic. Although 52 (22.6%) of the women were diagnosed as having bacterial vaginosis, none had symptoms of cervicitis or genital infection. Of the patients with bacterial vaginosis 19 (36.5%) had vaginal leucocytosis compared to 37.1% of the women without bacterial vaginosis. In a further study, bacterial vaginosis was also diagnosed in 104 of 384 women (33.3%) attending for first trimester legal abortions. Of the women with bacterial vaginosis 37.5% had vaginal leucocytosis compared to 31.8% for those without bacterial vaginosis (P greater than 0.05). There was no correlation between vaginal leucocytosis and the presence of cervical Chlamydia trachomatis; however, the presence of C. trachomatis did correlate with bacterial vaginosis. Vaginal leucocytes varies with factors unrelated to genital infection. This fact must be taken into consideration when wet smears from patients with suspected genital tract infection are evaluated.
authors.affiliation: Department of Obstetrics and Gynaecology, Central Hospital Skövde, Sweden.
authors.forename: P G
authors.initials: PG
authors.lastname: Larsson
authors.forename: J J
authors.initials: JJ
authors.lastname: Platz-Christensen
mesh_terms: D000293:Adolescent; D000328:Adult; D002690:Chlamydia Infections / Q000473:pathology; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D007962:Leukocytes / Q000473:pathology*; D008875:Middle Aged; D014621:Vagina / Q000473:pathology*; D016585:Vaginosis, Bacterial / Q000473:pathology*