title: [Coronary thrombosis, mechanisms of thrombolysis and the tactics in radiographically guided endovascular treatment of patients with acute myocardial infarction].
abstract: The radio-angiographic features of coronary blood flow were studied in 119 patients in the first 24 hours of a macrofocal myocardial infarction. In 100 (84%) patients with recognized occlusion of the coronary artery responsible for the infarction the semeiotics of the occluding coronary thrombosis is described, and the characteristics of the residual stenoses after intracoronary thrombolysis were studied. In more than 60% of cases the radiographic features of these stenoses were found to be similar to those of primarily revealed stenoses responsible for infarction of the coronary arteries in degree, form, and the presence of mural thrombus. The mechanism of the formation of these stenoses was of a common character--lysis of the occluding thrombus, which was medicinal in the first case and spontaneous in the second. Medicinal thrombolysis is an analogue of the natural physiological mechanism--spontaneous coronary thrombolysis. It was established that the process of medicinal lysis of the coronary thrombus, a mural thrombus among others, is fully completed by the end of the second day of myocardial infarction. The obtained information makes it possible to formulate some principles of radiologically-guided intravascular treatment of patients with myocardial infarction.
authors.forename: L S
authors.initials: LS
authors.lastname: Zingerman
authors.forename: G S
authors.initials: GS
authors.lastname: Topchiian
authors.forename: I E
authors.initials: IE
authors.lastname: Galankina
authors.forename: G E
authors.initials: GE
authors.lastname: Belozerov
authors.forename: T V
authors.initials: TV
authors.lastname: Zvereva
authors.forename: D V
authors.initials: DV
authors.lastname: Rudnev
mesh_terms: D000328:Adult; D000368:Aged; D015906:Angioplasty, Balloon, Coronary / Q000379:methods*; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D003331:Coronary Vessels / Q000187:drug effects; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D015912:Thrombolytic Therapy
chemical_list: D005343:Fibrinolytic Agents
vernacular_title: O koronarnom tromboze, mekhanizmakh trombolizisa i taktike rentgenoéndovaskuliarnogo lecheniia bol'nykh ostrym infarktom miokarda.