Newborn screening for cystic fibrosis: a historical perspective.
The historical development of blood immunoreactive trypsin as a screening procedure performed on neonatal dried blood is described. Our experience of false positive, and false positive results using the original procedure has led to some useful modifications which reduce these errors to an acceptable level. A satisfactory national screening programme has been in place in New Zealand for 10 years.
Elliott
R B
RB
Department of Paediatrics, School of Medicine, Aukland, New Zealand.
D003550:Cystic Fibrosis / Q000175:diagnosis / Q000266:history*; D049673:History, 20th Century; D006801:Humans; D007231:Infant, Newborn; D015997:Neonatal Screening / Q000266:history*; D009520:New Zealand; D014357:Trypsin / Q000097:blood
D014357:Trypsin