title: [Dynamic imaging with magnetic resonance in the diagnosis of breast disease].
abstract: MR imaging was employed for the identification and tissue characterization of nodular lesions in the breast. The study had poor outcome, but the clinical introduction of a paramagnetic contrast medium, Gd-DTPA, allowed better results to be obtained. This study was aimed at evaluating the possibilities of Gd-DTPA enhanced MRI in differentiating benign from malignant breast nodules and in staging cancer. Final diagnosis was made by means of either histology, in the patients who underwent surgery, or cytology. Sixty-one patients with nodules at mammography and US were examined with MRI. The results of US, mammography, and MRI were blindly evaluated and proved that combined mammography and US, together with Gd-DTPA enhanced MRI, correctly identified all nodular lesions. Moreover, enhanced MRI allowed benign lesions to be distinguished from malignant nodules. MRI with Gd-DTPA correctly assessed both T parameter and pectoral muscle infiltration. MRI cannot replace mammography, which is a quick and inexpensive examination, but it should be performed as an adjunct in the cases of questionable radiographic and US findings and to stage breast cancer.
authors.affiliation: Istituto di Semeiologia, Diagnostica e Terapia Strumentale Università, Ancona.
authors.forename: P
authors.initials: P
authors.lastname: Ercolani
authors.forename: A
authors.initials: A
authors.lastname: Giovagnoni
authors.forename: G
authors.initials: G
authors.lastname: Giuseppetti
authors.forename: S
authors.initials: S
authors.lastname: Baldassarre
authors.forename: E
authors.initials: E
authors.lastname: De Nigris
authors.forename: F
authors.initials: F
authors.lastname: Amici
mesh_terms: D000328:Adult; D000368:Aged; D001941:Breast Diseases / Q000175:diagnosis*; D001943:Breast Neoplasms / Q000175:diagnosis*; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA
vernacular_title: Imaging dinamico con risonanza magnetica nella senologia diagnostica.