title: Effect of a controlled-release albendazole capsule on parasitism and productivity of sheep.
abstract: The efficacy of intraruminal albendazole (ABZ) capsules (Profitril-Captec) and the effect of treatment on productivity were studied in 300 ewes infected with gastrointestinal nematodes and the trematode Dicrocoelium dendriticum. Coprological tests revealed that treated animals remained negative for 10 weeks after the administration of capsules. Contamination of pasture with nematode larvae was significantly reduced during the whole experiment. Necropsy of 14 animals (seven treated and seven untreated) showed 96.9-99.2% efficacy against the nematodes Nematodirus spp., Oesophagostomum spp., Cooperia spp., Trichostrongylus spp. and Trichuris ovis, while efficacy was 88.5% against D. dendriticum. During the 6 month pasture season (May-October 1989), treated ewes produced on average 2.56 kg cheese and 0.6 kg wool per ewe more than untreated controls. Our study confirms the reliability of the ABZ slow-release capsules over 90 days and the positive effect of treatment on nematode contamination of pasture and ewe productivity.
authors.affiliation: Helminthological Institute of the Slovak Academy of Sciences, Kosice, Czechoslovakia.
authors.forename: J
authors.initials: J
authors.lastname: Corba
authors.forename: I
authors.initials: I
authors.lastname: Krupicer
authors.forename: J
authors.initials: J
authors.lastname: Legény
authors.forename: P
authors.initials: P
authors.lastname: Juris
authors.forename: L
authors.initials: L
authors.lastname: Veselý
mesh_terms: D015766:Albendazole / Q000008:administration & dosage* / Q000627:therapeutic use; D000818:Animals; D002214:Capsules; D002611:Cheese; D003692:Delayed-Action Preparations; D005243:Feces / Q000469:parasitology; D005260:Female; D009348:Nematoda / Q000187:drug effects*; D009349:Nematode Infections / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D009814:Oesophagostomiasis / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary; D009815:Oesophagostomum / Q000187:drug effects; D010270:Parasite Egg Count / Q000662:veterinary; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy / Q000469:parasitology*; D014253:Trichostrongylosis / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary; D014254:Trichostrongylus / Q000187:drug effects; D014257:Trichuriasis / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary; D014258:Trichuris / Q000187:drug effects; D014935:Wool
chemical_list: D002214:Capsules; D003692:Delayed-Action Preparations; D015766:Albendazole