[Cardiac assist device with inserted alternate-drive skeletal muscle pump system].
Many studies on a skeletal muscle pump (SMP) for use as a cardiac assist device require preconditioning as a countermeasure to muscle fatigue. However, we conducted experiments in the hope of developing a cardiac assist device with an alternate-drive SMP system requiring no preconditioning. Adult mongrel dogs were used. We prepared a roll-type SMP from a pedicled muscle flap of the latissimus dorsi and major pectoris muscle, and an insert type SMP without separating the latissimus dorsi and major pectoris muscle. The muscles were stimulated at a frequency of 60 rpm at cycles of burst stimulation. Thirty-minute intermittent driving was performed. The hydrodynamic changes were measured at five-minute intervals for a total of three hours. The function of the pumps markedly declined after a few minutes of driving the roll-type SMPs but remained satisfactory after thirty minutes of driving the insert-type SMPs. Consequently, we concluded that dual SMPs, alternately driven through thirty minute intermittent drive and rest intervals, could be useful as cardiac assist devices without preconditioning.
Fujikawa
T
T
Second Department of Surgery, Tokyo Medical College, Japan.
Suesada
H
H
Shimizu
H
H
Osada
K
K
Hirayama
T
T
Ishimaru
S
S
Furukawa
K
K
D000818:Animals; D004285:Dogs; D004558:Electric Stimulation; D004867:Equipment Design; D006353:Heart-Assist Devices; D009132:Muscles