title: On the receiving end. IV: Validation of quality of life indicators.
abstract: Four measures of patient functioning and a mood adjective list currently used in trials of the International Breast Cancer Study Group (IBCSG), and an 8-item Linear Analogue Self Assessment (LASA) instrument measuring specific side effects of cancer and cancer treatment (GLQ-8), were cross-validated against three established measures of quality of life, mood and psychological adjustment to cancer, in a heterogeneous sample of cancer patients. Correlations between new and established measures were high, indicating good convergent and concurrent validity. Compliance on the longer mood measures was relatively poor. Despite the difficulty in developing direct and methodologically sound measures of quality of life, the regular inclusion of practical indicators of aspects of quality of life in clinical trials would allow improved assessment of the cost-benefit ratio of treatment to outcome in cancer patients.
authors.affiliation: Department of Medicine, University of Sydney, NSW, Australia.
authors.forename: P
authors.initials: P
authors.lastname: Butow
authors.forename: A
authors.initials: A
authors.lastname: Coates
authors.forename: S
authors.initials: S
authors.lastname: Dunn
authors.forename: J
authors.initials: J
authors.lastname: Bernhard
authors.forename: C
authors.initials: C
authors.lastname: Hürny
mesh_terms: D000223:Adaptation, Psychological; D000293:Adolescent; D000328:Adult; D000339:Affect; D000368:Aged; D001066:Appetite; D001315:Australia / Q000453:epidemiology; D003710:Demography; D005221:Fatigue; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009325:Nausea; D009369:Neoplasms / Q000523:psychology* / Q000628:therapy; D011581:Psychological Tests / Q000379:methods; D011788:Quality of Life