[Validation of the use of brachytherapy in uveal melanomas of juxtapapillary localization].
Forty-two patients with juxtacapillary melanomas of the choroid were treated by brachytherapy. The treatment was carried out in two stages: Stage I--separating laser coagulation, Stage II--irradiation with ophthalmologic applicators (90Sr, 90I). Complete resorption was achieved in 12 patients, partial regression with the process stabilization in 17, no effect in 13, in 11 of these enucleation had to be performed. The mean follow-up period has made up 6.8 years. Analysis of brachytherapy results has lead the authors to a conclusion that this treatment modality may be considered as enucleation alternative in patients with juxtacapillary melanomas located by the optic disk and covering not more than 1/3 of its perimeter, with the prominence of less than 3 mm; brachytherapy applicator in this case should be US monitored.
Brovkina
A F
AF
Zarubeĭ
G D
GD
Fishkin
Iu G
IuG
D001918:Brachytherapy; D005069:Evaluation Studies as Topic; D006801:Humans; D053685:Laser Therapy; D008545:Melanoma / Q000532:radiotherapy* / Q000601:surgery; D009898:Optic Disk; D013326:Strontium Radioisotopes / Q000008:administration & dosage; D014604:Uveal Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D015021:Yttrium Radioisotopes / Q000008:administration & dosage
D013326:Strontium Radioisotopes; D015021:Yttrium Radioisotopes
Obosnovannost' ispol'zovaniia brakhiterapii pri uveal'nykh melanomakh iukstapapilliarnoĭ lokalizatsii.