title: Adult-form galactosialidosis: ocular findings in three cases.
abstract: We reported ocular findings of 3 patients with adult-form galactosialidosis. Diffuse fine opacities in the deep layer of the corneal stroma, an obscure cherry-red spot of the macula and optic nerve atrophy were noted in all cases. Punctate lenticular opacities were observed in 2 cases. Slowly progressive visual disturbance was seen in all cases, and it might be due to secondary optic nerve atrophy caused by retinal ganglion cell death.
authors.affiliation: Department of Ophthalmology, Niigata University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Usui
authors.forename: M
authors.initials: M
authors.lastname: Takagi
authors.forename: H
authors.initials: H
authors.lastname: Abe
authors.forename: K
authors.initials: K
authors.lastname: Iwata
authors.forename: S
authors.initials: S
authors.lastname: Tsuji
authors.forename: T
authors.initials: T
authors.lastname: Miyatake
mesh_terms: D000328:Adult; D002386:Cataract / Q000473:pathology; D003318:Corneal Opacity / Q000473:pathology; D005128:Eye Diseases / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009439:Neuraminidase / Q000172:deficiency*; D009896:Optic Atrophy / Q000473:pathology; D012164:Retinal Diseases / Q000473:pathology; D001616:beta-Galactosidase / Q000172:deficiency*
chemical_list: D009439:Neuraminidase; D001616:beta-Galactosidase