title: [Effect of isoflurane on muscle relaxation in a patient with myotonic dystrophy].
abstract: We did anesthetic management by isoflurane for total thyroidectomy under the neuromuscular transmission monitoring in a patient with myotonic dystrophy. In three patients without neuromuscular disorders, T1 was 85% of control and fade was not observed, while in this case T1 was 40% of the control and TOFR was decreased to 50%. We conclude that isoflurane has a good muscle relaxation effect in this disease and, we could manage without administering any muscle relaxants.
authors.affiliation: Department of Anesthesiology, Akita University School of Medicine.
authors.forename: H
authors.initials: H
authors.lastname: Komatsu
authors.forename: T
authors.initials: T
authors.lastname: Horiguchi
authors.forename: K
authors.initials: K
authors.lastname: Enzan
authors.forename: W
authors.initials: W
authors.lastname: Satoh
authors.forename: K
authors.initials: K
authors.lastname: Shouji
authors.forename: M
authors.initials: M
authors.lastname: Suzuki
mesh_terms: D000328:Adult; D000769:Anesthesia, Inhalation; D005260:Female; D006801:Humans; D007530:Isoflurane / Q000494:pharmacology*; D009126:Muscle Relaxation / Q000187:drug effects*; D009223:Myotonic Dystrophy / Q000150:complications*; D013965:Thyroidectomy
chemical_list: D007530:Isoflurane