title: Changes of thymocyte subpopulations induced by activities diffusing from leukemia L1210 cells.
abstract: Mice with intraperitoneally inoculated leukemia L1210 cells had a lower total number of thymocytes and a markedly reduced percentage of L3T4+ Lyt2+ (CD4+ 8+) thymocytes, but increased subpopulations of L3T4+ Lyt2-, L3T4- Lyt2+, L3T4-Lyt2-. The percentage of Thy 1.2+ thymocytes was unchanged as compared with control animals. A similar effect was observed is suggested that leukemia L1210 cells produce some activities which diffuse through 0.22 microns filters and influence the subpopulations of thymocytes.
authors.affiliation: Department of Cytophysiology, Medical Centre of Postgraduate Education, Warsaw, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Kawiak
authors.forename: M
authors.initials: M
authors.lastname: Kawalec
authors.forename: G
authors.initials: G
authors.lastname: Hoser
authors.forename: B
authors.initials: B
authors.lastname: Miks
authors.forename: T
authors.initials: T
authors.lastname: Skórski
authors.forename: Z
authors.initials: Z
authors.lastname: Pojda
authors.forename: H
authors.initials: H
authors.lastname: Skurzak
mesh_terms: D000818:Animals; D015704:CD4 Antigens; D016827:CD8 Antigens; D002454:Cell Differentiation / Q000276:immunology*; D002461:Cell Line, Transformed / Q000276:immunology; D015194:Diffusion Chambers, Culture; D007939:Leukemia L1210 / Q000276:immunology*; D016131:Lymphocyte Subsets / Q000276:immunology*; D051379:Mice; D013950:Thymus Gland / Q000166:cytology / Q000276:immunology*
chemical_list: D015704:CD4 Antigens; D016827:CD8 Antigens