title: Replacement of the abdominal aorta with an aortic homograft in a patient with an aortic dissection.
abstract: The use of aortic and femoral homografts in early vascular surgery has been abandoned for the more successful and abundant synthetic substitutes. With the recent introduction of cryopreservation, homograft use has again met with improved success. A 40-year-old man who had a DeBakey Type I aortic dissection initially underwent replacement of the aortic root with a pulmonary homograft. Subsequently, in the presence of an intraabdominal infectious process, progressive mesenteric and lower limb ischemia was treated by replacing the abdominal aorta with an aortic homograft. Thirty-six months postoperative the patient has a functioning gastrointestinal tract and no vascular insufficiency of the lower extremities and no evidence of degeneration of the homograft. Further laboratory studies should be undertaken using the newer and improved cyropreserved homograft in the presence of, or potential for, an intraabdominal infectious process.
authors.affiliation: Department of Surgery, University of Oklahoma Health Sciences Center, Oklahoma City 73190.
authors.forename: J B
authors.initials: JB
authors.lastname: Steinberg
authors.forename: S A
authors.initials: SA
authors.lastname: Nickell
authors.forename: M A
authors.initials: MA
authors.lastname: Jacocks
authors.forename: P
authors.initials: P
authors.lastname: Stelzer
mesh_terms: D000328:Adult; D000784:Aortic Dissection / Q000601:surgery*; D001012:Aorta, Abdominal / Q000637:transplantation*; D001014:Aortic Aneurysm / Q000601:surgery*; D006801:Humans; D007511:Ischemia / Q000601:surgery; D007866:Leg / Q000098:blood supply; D008297:Male; D008638:Mesenteric Arteries / Q000473:pathology; D011651:Pulmonary Artery / Q000637:transplantation; D012086:Reoperation