Crystallographic refinement of bovine pro-phospholipase A2 at 1.6 A resolution.
Bovine pro-phospholipase A2 (Mr = 14,520), trigonal, P3(1)21, a = b = 46.5, c = 102.0 A, one molecule per asymmetric unit, lambda (Cu K alpha) = 1.54 A. The model incorporating 895 protein atoms, two molecules of 2-methyl-2,4-pentanediol, and 60 solvent water molecules, was refined by restrained least squares to a residual R = 0.194 for 14,667 reflections from 5 to 1.6 A resolution.
Finzel
B C
BC
DuPont Merck Pharmaceutical Company, Wilmington, DE 19880-0228.
Weber
P C
PC
Ohlendorf
D H
DH
Salemme
F R
FR
D004792:Enzyme Precursors / Q000737:chemistry*; D010741:Phospholipases A / Q000737:chemistry*; D014961:X-Ray Diffraction
D004792:Enzyme Precursors; D010741:Phospholipases A