title: [Midazolam as a premedicant for trigeminal nerve blocks].
abstract: Although patients with trigeminal neuralgia can be treated satisfactorily with nerve blocks, the block procedure is sometimes very painful and uncomfortable for them. To investigate the efficacy and adverse effects of midazolam as a premedicant for trigeminal nerve blocks, 19 patients were randomly assigned to receive either midazolam (0.05 mg.kg-1, n = 6), midazolam (0.1 mg.kg-1, n = 7), or saline/placebo (n = 6) before the block. The patients given midazolam (0.1 mg.kg-1) had a significantly lower incidence of recalling the block procedure and had complained of less discomfort when interviewed the following day. No serious adverse effects were observed in any patient given midazolam. Midazolam can be used safely as an effective premedicant for potentially uncomfortable procedures such as trigeminal nerve blocks.
authors.affiliation: Department of Anesthesiology, Gifu University School of Medicine.
authors.forename: H
authors.initials: H
authors.lastname: Iida
authors.forename: M
authors.initials: M
authors.lastname: Takenaka
authors.forename: T
authors.initials: T
authors.lastname: Tanahashi
authors.forename: H
authors.initials: H
authors.lastname: Shimonaka
authors.forename: S
authors.initials: S
authors.lastname: Dohi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008874:Midazolam; D008875:Middle Aged; D009407:Nerve Block; D011229:Preanesthetic Medication; D014276:Trigeminal Nerve; D014277:Trigeminal Neuralgia / Q000601:surgery*
chemical_list: D008874:Midazolam