[Massive intravascular hemolysis in septicemia caused by Clostridium perfringens].
A case of massive haemolytic anaemia in the course of a C. perfringens sepsis of hepatic origin is presented. The diagnosis was strongly suggested by the presence of intragranulocytic capsulated bacilli in a Giemsa stained peripheral blood smear. The patient developed disseminated intravascular coagulation. The outcome was fatal and the patient died eight hours after admission. We review the aetiopathogenesis, diagnosis and therapy of haemolysis in Clostridium perfringens infections.
Borrego
D
D
Servicio de Hematologia del Hospital de Elda, SVS.
María-Tome
P
P
Cascales
P
P
García Aguayo
J M
JM
Pérez Amoros
G
G
Abad
A
A
D000368:Aged; D000743:Anemia, Hemolytic / Q000209:etiology*; D001427:Bacterial Toxins / Q000494:pharmacology; D002135:Calcium-Binding Proteins; D003015:Clostridium Infections / Q000097:blood / Q000150:complications*; D003016:Clostridium perfringens; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D006801:Humans; D008100:Liver Abscess / Q000382:microbiology; D008297:Male; D018805:Sepsis / Q000097:blood / Q000150:complications* / Q000382:microbiology; D010738:Type C Phospholipases
D001427:Bacterial Toxins; D002135:Calcium-Binding Proteins; D010738:Type C Phospholipases; C040649:alpha toxin, Clostridium perfringens
Hemólisis intravascular masiva en septicemia por Clostridium perfringens.