title: [Critical aortic stenosis in newborn infants. Twenty-five years' experience].
abstract: Operative mortality for critical aortic stenosis in newborn having been reported as high as 20-80%, the percutaneous aortic valvuloplasty is looked upon as an alternative therapy. We elected to review our surgical experience in the last 25 years before changing our therapeutic approach. Among 37 infants included in the study, 28 were boys and 9 girls. Mean age at diagnosis was 14.5 days (1 to 113 days) and decreased to 4.1 days in the last 5 years. Surgery was done at a mean of 37.2 days; 22 infants were operated on before one month of age and 9 in their first week of life. Five died from ventricular fibrillation at incision. Trans-ventricular valvulotomy was attempted in 4 and remaining 28 had trans aortic valvuloplasty. The overall survival of 40% had improved in last five years to 75%. All patients with trans-ventricular approach died and also did the only child with percutaneous angioplasty. Only 13% patients weighing less than 3 kg survived the operation. Follow-up was of 93.3% with a mean time of 66 months. All but one are in NYHA class 1 or 2. Our study identified the following risk factors: preoperative hemodynamic state, surgical weight, associated anomalies of the left ventricle, transventricular valvulotomy and the year of surgery. In view of improved survival, surgery remains a good therapeutic choice.
authors.affiliation: Service de Chirurgie Cardiaque, Hôpital Sainte-Justine, Montréal, Québec, Canada.
authors.forename: S J
authors.initials: SJ
authors.lastname: Vobecky
authors.forename: C
authors.initials: C
authors.lastname: Chartrand
authors.forename: H
authors.initials: H
authors.lastname: Yangni-Angaté
authors.forename: P
authors.initials: P
authors.lastname: Stanley
mesh_terms: D001024:Aortic Valve Stenosis / Q000151:congenital / Q000503:physiopathology / Q000601:surgery*; D001835:Body Weight; D005112:Extracorporeal Circulation / Q000379:methods; D005260:Female; D006350:Heart Valve Prosthesis / Q000401:mortality*; D006352:Heart Ventricles / Q000503:physiopathology; D006439:Hemodynamics; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011379:Prognosis; D012307:Risk Factors
vernacular_title: Sténose aortique critique du nouveau-né. Expérience de vingt-cinq ans.