title: Research on antibacterial and antifungal agents. IX--Synthesis and microbiological activity of new N-arylpyrroles.
abstract: The synthesis and antiblastomycete activity of new N-arylpyrrole derivatives are reported. Antimicrobial data in comparison with those obtained with pyrrolnitrin and miconazole showed that all tested compounds possess weak or poor activity. The obtained results are discussed on the basis of structure-activity relationships.
authors.affiliation: Dipartimento di Studi di Chimica, Università Degli Studi di Roma La Sapienza, Italy.
authors.forename: G C
authors.initials: GC
authors.lastname: Porretta
authors.forename: M
authors.initials: M
authors.lastname: Biava
authors.forename: R
authors.initials: R
authors.lastname: Fioravanti
authors.forename: A
authors.initials: A
authors.lastname: Villa
authors.forename: N
authors.initials: N
authors.lastname: Simonetti
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis*; D002175:Candida / Q000187:drug effects; D005658:Fungi / Q000187:drug effects; D008825:Miconazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D011758:Pyrroles / Q000138:chemical synthesis* / Q000494:pharmacology; D011764:Pyrrolnitrin / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D000935:Antifungal Agents; D011758:Pyrroles; D008825:Miconazole; D011764:Pyrrolnitrin