title: Experimental CNS tumors in rats. Testing field for a computerized classification and tumor grading.
abstract: The purpose of this study was to verify the efficiency of a previously described method for the computerized histological diagnosis of experimental brain tumors (Kroh et al. 1988). 117 tumors (astrocytomas, glioblastomas, meningosarcomas, neurinomas, oligoastrocytomas and oligodendrogliomas), experimentally induced in rats, were studied. In every case the same 50 histological characteristics used for the elaboration of a computerized system for the diagnosis of experimental brain tumors in mice were analyzed. Our results demonstrate the efficiency of this diagnostic method for experimental brain tumors. Furthermore, the grade of malignancy of these tumors was also determined by using a previously described computer program.
authors.affiliation: Katharinenhospital, Institute of Pathology, Stuttgart, Germany.
authors.forename: J R
authors.initials: JR
authors.lastname: Iglesias
authors.forename: H
authors.initials: H
authors.lastname: Kroh
authors.forename: A
authors.initials: A
authors.lastname: Matyja
authors.forename: C
authors.initials: C
authors.lastname: Aruffo
mesh_terms: D000818:Animals; D001932:Brain Neoplasms / Q000139:chemically induced / Q000145:classification*; D003936:Diagnosis, Computer-Assisted; D005038:Ethylnitrosourea; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D005038:Ethylnitrosourea