Ultrastructural analysis of noradrenergic nerve terminals in the cat lumbosacral spinal dorsal horn: a dopamine-beta-hydroxylase immunocytochemical study.
Noradrenaline-containing nerve terminals within the cat spinal dorsal horn were studied by immunocytochemical localization of dopamine-beta-hydroxylase. Immunoreactive terminals formed symmetrical (Gray type II) synaptic specializations with dendrites and somata throughout laminae I-IV, but no junctions were formed with other axons. These findings suggest that noradrenaline regulates sensory transmission through the dorsal horn via a postsynaptic action.
Doyle
C A
CA
Department of Preclinical Veterinary Sciences, University of Edinburgh, U.K.
Maxwell
D J
DJ
D000818:Animals; D002415:Cats; D004299:Dopamine beta-Hydroxylase / Q000276:immunology*; D005260:Female; D007150:Immunohistochemistry; D009411:Nerve Endings / Q000201:enzymology / Q000648:ultrastructure*; D009638:Norepinephrine / Q000502:physiology; D013116:Spinal Cord / Q000201:enzymology / Q000648:ultrastructure*; D013569:Synapses / Q000648:ultrastructure
D004299:Dopamine beta-Hydroxylase; D009638:Norepinephrine