[Treatment of climacteric syndrome with new gengnian prescriptions].
It was found by the observations of clinical treatment that the three indexes of epinephrine(E), norepinephrine(NE) and dopamine(D) of urinary catecholamine(CA) increased (P less than 0.001, P less than 0.05 and P less than 0.001) for the climacteric patients who suffered from the deficiency of Yin leading to the hyperactivity of the internal heat of the heart, and the urinary 17-hydroxycorticosteroid (17-OHCS) increased (P less than 0.001) for the patients who suffered from the deficiency of Yin leading to the hyperactivity of the internal heat of the liver. Both the three indexes and urinary 17-OHCS increased for the two groups (P less than 0.01). However, for all the above groups who suffered from the deficiency of Yin leading to the hyperactivity of the internal heat, the NE/E ratio was larger than the normal ratio, which stands for the level of central catecholamine. After the treatment with new Gengnian prescriptions, the clinical symptoms of the patients were improved, and in the meantime urinary CA. 17-OHCS and NE/E were decreased. The total efficiency was 89.2%. The principle of treatment with this prescription may be due to the fact that the level of central catecholamine decreased so that the excessive excitation of sympathetics-adrenocortical system and sympathetics-adrenocortical system was restrained.
Lu
Q B
QB
Jiangsu Hospital of TCM, Nanjing.
Xia
G C
GC
Chen
D H
DH
D015065:17-Hydroxycorticosteroids / Q000652:urine; D000328:Adult; D002395:Catecholamines / Q000652:urine; D002979:Climacteric / Q000187:drug effects* / Q000652:urine; D003863:Depression / Q000188:drug therapy; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008875:Middle Aged; D013577:Syndrome; D016710:Yin Deficiency / Q000188:drug therapy*
D015065:17-Hydroxycorticosteroids; D002395:Catecholamines; D004365:Drugs, Chinese Herbal