title: An experimental evaluation of possible teratogenic potential in Boerhaavia diffusa in Albino rats.
abstract: The present study was undertaken to evaluate any possibility of teratogenic effects in Boerhaavia diffusa (Punarnava), a widely used herbal medicine for renal and urinary tract diseases by Ayurvedic physicians in India. The ethanolic extract of Boerhaavia diffusa (BDE) was administered daily in a dose of 250 mg/kg, body weight p.o., to pregnant albino female rats during the entire period of gestation. BDE was found to be devoid of any teratogenic effect as litter size and survival rate of foetuses were the same as for the normal control group and no foetal anomaly could be detected.
authors.affiliation: Department of Nephrology and Kayachikitsa, Banaras University, Varanasi, India.
authors.forename: A
authors.initials: A
authors.lastname: Singh
authors.forename: R G
authors.initials: RG
authors.lastname: Singh
authors.forename: R H
authors.initials: RH
authors.lastname: Singh
authors.forename: N
authors.initials: N
authors.lastname: Mishra
authors.forename: N
authors.initials: N
authors.lastname: Singh
mesh_terms: D000818:Animals; D005260:Female; D008515:Medicine, Ayurvedic; D010946:Plants, Medicinal; D011247:Pregnancy; D051381:Rats; D013723:Teratogens
chemical_list: D013723:Teratogens