title: [Massive intravascular hemolysis in septicemia caused by Clostridium perfringens].
abstract: A case of massive haemolytic anaemia in the course of a C. perfringens sepsis of hepatic origin is presented. The diagnosis was strongly suggested by the presence of intragranulocytic capsulated bacilli in a Giemsa stained peripheral blood smear. The patient developed disseminated intravascular coagulation. The outcome was fatal and the patient died eight hours after admission. We review the aetiopathogenesis, diagnosis and therapy of haemolysis in Clostridium perfringens infections.
authors.affiliation: Servicio de Hematologia del Hospital de Elda, SVS.
authors.forename: D
authors.initials: D
authors.lastname: Borrego
authors.forename: P
authors.initials: P
authors.lastname: María-Tome
authors.forename: P
authors.initials: P
authors.lastname: Cascales
authors.forename: J M
authors.initials: JM
authors.lastname: García Aguayo
authors.forename: G
authors.initials: G
authors.lastname: Pérez Amoros
authors.forename: A
authors.initials: A
authors.lastname: Abad
mesh_terms: D000368:Aged; D000743:Anemia, Hemolytic / Q000209:etiology*; D001427:Bacterial Toxins / Q000494:pharmacology; D002135:Calcium-Binding Proteins; D003015:Clostridium Infections / Q000097:blood / Q000150:complications*; D003016:Clostridium perfringens; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D006801:Humans; D008100:Liver Abscess / Q000382:microbiology; D008297:Male; D018805:Sepsis / Q000097:blood / Q000150:complications* / Q000382:microbiology; D010738:Type C Phospholipases
chemical_list: D001427:Bacterial Toxins; D002135:Calcium-Binding Proteins; D010738:Type C Phospholipases; C040649:alpha toxin, Clostridium perfringens
vernacular_title: Hemólisis intravascular masiva en septicemia por Clostridium perfringens.