title: 3-D treatment planning and dose delivery verification integrating a variety of state-of-the-art techniques: a case report.
abstract: A patient previously treated with radiation for base-of-tongue cancer presented with recurrent disease seven years later. The spinal cord had received tolerance dose. Using state-of-the-art treatment planning techniques, including beam's-eye-view and volumetrics, dose-volume histograms, split field technique, mixed energies, and beam intensity modulation (with a compensator), we achieved uniform dose coverage of the target in 3-D. This was verified in vivo with thermoluminescence dosimeters positioned in the esophagus by means of a nasogastric tube that ran centrally through the target volume. The various techniques applied will be presented with a discussion of the rationale used in each step of plan optimization and verification.
authors.affiliation: Department of Radiation and Cellular Oncology, University of Chicago, IL 60637.
authors.forename: F T
authors.initials: FT
authors.lastname: Kuchnir
authors.forename: S
authors.initials: S
authors.lastname: Watson-Bullock
authors.forename: C S
authors.initials: CS
authors.lastname: Reft
authors.forename: D
authors.initials: D
authors.lastname: Hallahan
mesh_terms: D007091:Image Processing, Computer-Assisted; D009364:Neoplasm Recurrence, Local / Q000532:radiotherapy*; D011880:Radiotherapy Planning, Computer-Assisted; D014062:Tongue Neoplasms / Q000532:radiotherapy*