title: Dihalomethyl compounds as mechanism-based inactivators of cytochromes P450.
authors.forename: J R
authors.initials: JR
authors.lastname: Halpert
authors.forename: J C
authors.initials: JC
authors.lastname: Stevens
mesh_terms: D000081:Acetamides / Q000494:pharmacology*; D000818:Animals; D002250:Carbon Radioisotopes; D065607:Cytochrome P-450 Enzyme Inhibitors; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006846:Hydrocarbons, Halogenated / Q000494:pharmacology*; D007527:Isoenzymes / Q000037:antagonists & inhibitors*; D007700:Kinetics; D008862:Microsomes, Liver / Q000201:enzymology; D011865:Radioisotope Dilution Technique; D051381:Rats
chemical_list: D000081:Acetamides; D002250:Carbon Radioisotopes; D065607:Cytochrome P-450 Enzyme Inhibitors; D004791:Enzyme Inhibitors; D006846:Hydrocarbons, Halogenated; D007527:Isoenzymes