[The content of stable forms of prostacyclin I2 and thromboxane A2 in the blood plasma in diabetic angiopathies].
Altogether 33 patients with insulin-dependent, 51 patients with noninsulin-dependent diabetes mellitus, and 17 patients with atherosclerosis with the affected lower limb major vessels were investigated. The levels of stable forms of prostacyclin I2 and thromboxane A2 were studied with relation to the nature and degree of vascular disorders. Diabetes mellitus and progress of diabetic angiopathies were accompanied by a more pronounced increase in the level of thromboxane B2 and a decrease in the level of 6-ketoprostaglandin F1. An increase in the ratio of thromboxane B2/6-ketoprostaglandin F1 could be interpreted as a prognostically unfavorable sign, suggestive of progression of diabetic angiopathy. It was recommended to study the efficacy and potentialities of correction of disorders with concentrates of ethers of unsaturated fatty acids.
Sergienko
A A
AA
D015121:6-Ketoprostaglandin F1 alpha / Q000097:blood; D000293:Adolescent; D000328:Adult; D000368:Aged; D001161:Arteriosclerosis / Q000097:blood; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000150:complications; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications; D003925:Diabetic Angiopathies / Q000097:blood*; D011464:Epoprostenol / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013928:Thromboxane A2 / Q000097:blood*; D013929:Thromboxane B2 / Q000097:blood
D013929:Thromboxane B2; D013928:Thromboxane A2; D015121:6-Ketoprostaglandin F1 alpha; D011464:Epoprostenol
Soderzhanie stabil'nykh form prostatsiklina I2, tromboksana A2 v plazme krovi pri diabeticheskikh angiopatiiakh.