Short-term nonconjugate adaptation of human saccades to anisometropic spectacles.
It has been demonstrated before that the long-term wearing of anisometropic spectacles may induce nonconjugate adaptations of saccades. Saccades then become different in size in the two eyes. We examined the time-course and the limits of such adaptations of horizontal and vertical saccades during the short-term (1-6 hr) wearing of anisometropic spectacles. After only 1 hr of conditioning to 2 D of anisometropia, the nonconjugate size-adaptations were almost complete along the horizontal meridian. For progressively larger anisometropias (up to 8 D) the adaptative nonconjugacies after 1 hr became also systematically larger. An anisometropia larger than 6 D did not further increase the rate of adaptation during the first 6 hr of conditioning, which suggests that about 6 D of difference in spectacle correction, causing size differences of about 12%, may be the upper limit of the nonconjugate adaptive range of the saccadic subsystem. Post-saccadic drift of horizontal saccades was also adequately changed. In addition, nonconjugate adaptations had developed in smooth-pursuit eye movements. All of these plastic changes persisted during monocular viewing, indicating that the basic programming of these eye movements was changed.
Lemij
H G
HG
Department of Physiology I, Faculty of Medicine, Erasmus University Rotterdam, The Netherlands.
Collewijn
H
H
D000221:Adaptation, Ocular / Q000502:physiology*; D000328:Adult; D015858:Anisometropia / Q000503:physiopathology*; D005139:Eyeglasses; D006801:Humans; D011698:Pursuit, Smooth / Q000502:physiology; D012438:Saccades / Q000502:physiology*; D013997:Time Factors; D015349:Vision, Monocular / Q000502:physiology