The successful medical management of gastric outflow obstruction associated with the use of non-steroidal anti-inflammatory drugs in the elderly.
One hundred and nineteen consecutive elderly patients with endoscopically diagnosed peptic ulceration were reviewed. Associated gastric outflow obstruction was present in 10.1%. The presenting clinical features differed significantly from typical younger patients and most (11/12) were taking non-steroidal anti-inflammatory drugs, suggesting a possible role for these agents in the pathogenesis of gastric outflow obstruction. These elderly patients have been successfully managed by medical therapy alone.
Geraghty
R J
RJ
Queen Mary's Hospital, Sidcup, Kent, UK.
Black
D
D
Bruce
S A
SA
D000368:Aged; D000369:Aged, 80 and over; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D002927:Cimetidine / Q000627:therapeutic use; D004380:Duodenal Obstruction / Q000139:chemically induced / Q000188:drug therapy; D005260:Female; D005746:Gastric Emptying / Q000187:drug effects*; D006801:Humans; D008297:Male; D010437:Peptic Ulcer / Q000150:complications; D011707:Pyloric Stenosis / Q000139:chemically induced* / Q000188:drug therapy; D011899:Ranitidine / Q000627:therapeutic use
D000894:Anti-Inflammatory Agents, Non-Steroidal; D002927:Cimetidine; D011899:Ranitidine