[Effect of hyperbaric factors on the biochemical and hematological indicators in rats (in vivo) and in humans (in vitro)].
The influence of hyperbaric factors on complex of biochemical and haematological parameters was examined in rats (in vivo) on donor blood samples. It was established, that the sojourn in heliox under the pressure 6.1 MPa and rO2 60 kPa results in activation of lipid peroxidation, alteration of erythrocyte oxygen transport function and the suppression of lipid metabolism. There are no significant alterations of these parameters in the comparative experiment with the pO2 40 kPa. The decompression of donor blood samples from 5.1 MPa to 0.1 MPa during 50 minutes had no significant influence on complex of biochemical, haematological and immunological parameters as compared to control probes.
Ryzhova
T I
TI
Ganenko
S I
SI
Povazhenko
A A
AA
Sukhapovskaia
N S
NS
D000328:Adult; D000818:Animals; D001273:Atmosphere Exposure Chambers; D002374:Catalase / Q000097:blood; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism*; D006019:Glycolysis / Q000187:drug effects / Q000502:physiology; D006371:Helium / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D006931:Hyperbaric Oxygenation; D066298:In Vitro Techniques; D007770:L-Lactate Dehydrogenase / Q000097:blood; D015227:Lipid Peroxidation / Q000187:drug effects / Q000502:physiology; D008297:Male; D008954:Models, Biological; D010100:Oxygen / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D051381:Rats; D013482:Superoxide Dismutase / Q000097:blood; D013997:Time Factors
D006371:Helium; C038949:heliox; D007770:L-Lactate Dehydrogenase; D002374:Catalase; D013482:Superoxide Dismutase; D010100:Oxygen
Vliianie faktorov giperbarii na biokhimicheskie i gematologicheskie pokazateli u krys (in vivo) i cheloveka (in vitro).