[Status of immunity in newborn infants and young children born to mothers with tuberculosis].
The children born to tuberculosis mothers show a decline in T-lymphocyte count and in their functional activity, an increase in specific immunity parameters, which is manifested by a higher level of antituberculosis antibodies and a marked proliferative lymphocyte response to tuberculin. It has been established that the level of specific antibodies in children and their mothers is related to the clinical form of tuberculosis. The discovered features of specific and nonspecific immunity in newborns and infants born to tuberculosis mothers should be considered in the organization of preventive measures in this group of children.
Zakharova
R I
RI
Vakhidova
G A
GA
Biriukova
L A
LA
Namazov
S H
SH
D000328:Adult; D000367:Age Factors; D000907:Antibodies, Bacterial / Q000032:analysis; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007112:Immunity, Maternally-Acquired / Q000276:immunology*; D007136:Immunoglobulins / Q000032:analysis*; D007223:Infant; D007231:Infant, Newborn / Q000276:immunology*; D008297:Male; D009169:Mycobacterium tuberculosis / Q000276:immunology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology* / Q000382:microbiology; D013601:T-Lymphocytes / Q000276:immunology*; D014397:Tuberculosis, Pulmonary / Q000276:immunology* / Q000382:microbiology
D000907:Antibodies, Bacterial; D007136:Immunoglobulins
Sostoianie immuniteta u novorozhdennykh i deteĭ rannego vozrasta, rodivshikhsia ot bol'nykh tuberkulezom matereĭ.