Relationships between hair-follicle afferent axons and glycine-immunoreactive profiles in cat spinal dorsal horn.
In order to identify synapses between hair-follicle afferent axons and glycine-containing structures in cat spinal cord, semithin sections containing physiologically identified primary afferent boutons which had been filled with horseradish peroxidase (HRP) were reacted with anti-glycine antiserum, while adjacent ultrathin sections were examined for synaptic contacts. Four axodendritic synapses between hair-follicle afferent boutons and glycine-immunoreactive dendrites and 4 axoaxonic synapses in which HRP-filled boutons were postsynaptic to immunoreactive axons were identified. These results suggest that glycine is involved in the spinal processing of input from A beta hair-follicle afferent axons.
Todd
A J
AJ
Department of Anatomy, University of Glasgow, U.K.
Maxwell
D J
DJ
Brown
A G
AG
D000818:Animals; D001369:Axons / Q000502:physiology* / Q000648:ultrastructure; D002415:Cats; D005998:Glycine / Q000276:immunology / Q000378:metabolism*; D006197:Hair / Q000502:physiology*; D006735:Horseradish Peroxidase; D007150:Immunohistochemistry; D007395:Interneurons / Q000502:physiology / Q000648:ultrastructure; D009475:Neurons, Afferent / Q000502:physiology* / Q000648:ultrastructure; D013116:Spinal Cord / Q000166:cytology* / Q000276:immunology / Q000648:ultrastructure
D006735:Horseradish Peroxidase; D005998:Glycine