title: [Direct infusion of drug mixture into the aorta in the treatment of necrotizing pancreatitis].
abstract: The article analyses briefly the methods of modern treatment of destructive pancreatitis. The authors apply complex treatment the principal component of which is infusion of a drug mixture into the aorta after its direct puncture at the level of the 8th-9th thoracic vertebra. The mixture consists of procaine hydrochloride solution, heparin, morphocycline, ftorafur , diphenylhydramine hydrochloride, trimeperidine hydrochloride. Before the aorta is punctured, 100-150 ml of a procaine hydrochloride solution is injected into the paraaortic fat to block the celiac and vagus nerves and the solar plexus. In a period of 9 years 138 patients underwent such treatment. Comparative study showed that the method differed favourably from that in which intraaortic infusion of drugs and blockade of the mediastinal nerve elements were not applied. The mortality was 8.33 in the first and 27.8% in the second group.
authors.forename: V A
authors.initials: VA
authors.lastname: Goldin
authors.forename: Z E
authors.initials: ZE
authors.lastname: Egbe
mesh_terms: D000328:Adult; D001011:Aorta / Q000187:drug effects; D002447:Celiac Plexus / Q000187:drug effects*; D004338:Drug Combinations; D006801:Humans; D007269:Injections, Intra-Arterial; D008875:Middle Aged; D009336:Necrosis; D009407:Nerve Block; D010179:Pancreas / Q000187:drug effects / Q000294:innervation* / Q000473:pathology; D010195:Pancreatitis / Q000188:drug therapy* / Q000473:pathology; D011343:Procaine / Q000008:administration & dosage*; D012965:Sodium Chloride / Q000008:administration & dosage*
chemical_list: D004338:Drug Combinations; D012965:Sodium Chloride; D011343:Procaine
vernacular_title: Priamaia infuziia lekarstvennoĭ smesi v aortu pri lechenii pankreonekroza.