Haemarthrosis in patients with mild coagulation factor deficiency.
While haemarthrosis is a common finding in severe factor VIII or IX deficiency, it is unusual in mild coagulation factor deficiencies. We describe three patients with mild factor IX, X or XI deficiency who presented with spontaneous haemarthrosis. All underwent joint puncture with subsequent worsening of the haemarthrosis in the affected joint. This report indicates that: (i) even mild coagulation factor deficiency may be associated with haemarthrosis; (ii) patients with suspected haemarthrosis should undergo routine screening coagulation tests before joint puncture; and (iii) any abnormalities in the screening tests indicate a need for further evaluation of the coagulation status. In such cases puncture of the joint should be deferred and specific therapy started immediately.
Bairey
O
O
Division of Hematology, Beilinson Medical Center, Petah Tiqva, Israel.
Shaklai
M
M
Inbal
A
A
D000328:Adult; D000368:Aged; D005171:Factor X Deficiency / Q000150:complications*; D005173:Factor XI Deficiency / Q000150:complications*; D005260:Female; D006395:Hemarthrosis / Q000097:blood / Q000209:etiology*; D002836:Hemophilia B / Q000150:complications*; D006801:Humans; D008297:Male; D012720:Severity of Illness Index