title: Composite tragal perichondrial/cartilage autografts vs cartilage or bone paste grafts in tympanoplasty.
abstract: Extrusion of plastic or ceramic implants is a significant cause of failure in ossiculoplasty for chronic ear disease. This paper reports the use of a composite tragal cartilage and perichondrial autograft compared to cartilage or bone paste between the graft and tympanic membrane. At 2 years, there were no extrusions in the group with the composite graft (n = 18) and 5 extrusions in the cartilage/bone paste group (n = 18) (P = 0.02). The mean average air-bone gap was significantly better for the composite grafts at 2 years (15 dB vs 24 dB) (P less than 0.05). Extrusions were eliminated and hearing results better at 2 years using the composite graft.
authors.affiliation: Virginia Mason Clinic, Seattle, Washington.
authors.forename: C A
authors.initials: CA
authors.lastname: East
authors.forename: C A
authors.initials: CA
authors.lastname: Mangham
mesh_terms: D001672:Biocompatible Materials; D001844:Bone Conduction / Q000502:physiology; D016025:Bone Transplantation / Q000379:methods* / Q000473:pathology; D002356:Cartilage / Q000473:pathology / Q000637:transplantation*; D002516:Ceramics; D003238:Connective Tissue / Q000473:pathology / Q000637:transplantation; D005500:Follow-Up Studies; D006309:Hearing / Q000502:physiology; D006801:Humans; D009998:Ossicular Prosthesis; D011095:Polyethylenes; D011126:Polypropylenes; D011474:Prosthesis Design; D012189:Retrospective Studies; D014433:Tympanoplasty / Q000379:methods*
chemical_list: D001672:Biocompatible Materials; C016674:Plastipore; D011095:Polyethylenes; D011126:Polypropylenes; C031323:bio-vitroceramic AP40