Photophysics and photochemistry of new verdin compounds.
Five different verdins, including one zinc metal chelate, were examined by laser flash techniques. Triplet molar absorption coefficients, triplet and singlet oxygen quantum yields and triplet lifetimes were determined. Zinc methyl pyroverdin (ZNMPV), copro II verdin trimethyl ester (CVTME) and deuteroverdin methyl ester (DVME) have the highest triplet and singlet oxygen quantum yields. ZNMPV and CVTME have the longest triplet lifetimes. Our data are consistent with singlet oxygen as the primary modality for phototherapy and it is suggested that DVME and CVTME may be useful agents.
Becker
R S
RS
Department of Chemistry, University of Houston, TX 77204-5641.
Das
S
S
Chakravorti
S
S
Morgan
A R
AR
D007834:Lasers; D015394:Molecular Structure; D010782:Photolysis; D011166:Porphyrins / Q000138:chemical synthesis / Q000737:chemistry* / Q000528:radiation effects; D011838:Radiation-Sensitizing Agents / Q000737:chemistry*; D013329:Structure-Activity Relationship
D011166:Porphyrins; D011838:Radiation-Sensitizing Agents; C054069:verdin