[The body muscle compartment and its relationship to food absorption and blood chemistry during an extreme endurance performance].
The purpose of the study was to examine the changes of the muscle's fat-free compartment and its relation to the corresponding biochemical and nutritional parameters of 42 men and 13 women, the participants of an ultra long-distance run of 1000 km (20 days of daily running 50 km). The muscle-fractions initially increased, decreased in the middle phase, and remained stable for the rest of the run. Significant changes of the fat-free weight were registered from the 11th day on, the LBM decreasing until the middle of the distance; then the lean body mass enlarged. All the muscle-circumferences were reduced with the exception of the thigh, which grew, paralleling the CK/CKMB-concentrations, this phenomenon being due to the high mechanical stress of the lower extremities. The biochemical parameters exhibit a strain-related reaction of adaptation within the initial 6 days, the hormones and protein-concentration increasing in the beginning and falling from the third day on, uric acid and CK/CKMB-activity decreasing from the 6th day on. The consecutive parallel reduction of both uric acid, urea, and muscle measurements might be seen as a special endurance-related clearance-mechanism of potential toxicants. The negative relationship between the changes of muscle measurements and the cumulative protein intake and the catabolic constellation of the clinical-chemical values might suggest that the absolute protein intake of 1.7 g/kg body mass should be increased in order to diminish the loss of musculature during an ultra-long distance run.
Raschka
C
C
Institut für Anthropologie, Universität Mainz.
Plath
M
M
Cerull
R
R
Bernhard
W
W
Jung
K
K
Leitzmann
C
C
D000042:Absorption; D000886:Anthropometry; D001774:Blood Chemical Analysis; D001798:Blood Proteins / Q000032:analysis; D001835:Body Weight; D003402:Creatine Kinase / Q000097:blood*; D004044:Dietary Proteins / Q000008:administration & dosage / Q000378:metabolism*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007527:Isoenzymes; D008297:Male; D024510:Muscle Development; D009132:Muscles / Q000378:metabolism / Q000473:pathology*; D005082:Physical Exertion / Q000502:physiology*; D012420:Running; D013739:Testosterone / Q000097:blood; D014508:Urea / Q000097:blood; D014527:Uric Acid / Q000097:blood
D001798:Blood Proteins; D004044:Dietary Proteins; D007527:Isoenzymes; D014527:Uric Acid; D013739:Testosterone; D014508:Urea; D003402:Creatine Kinase; D006854:Hydrocortisone
Das Körpermuskelkompartiment und seine Beziehungen zu Nahrungsaufnahme und Blutchemie unter einer extremen Ausdauerbelastung.