Decreased metabolic rate as an acrolein resistance mechanism in Drosophila melanogaster.
Using several mutant strains of Drosophila melanogaster, with different degrees of spontaneous activity, we have studied whether a decreased metabolic rate, measured by oxygen consumption, might be one of the mechanisms involved in acrolein resistance, such as predicted by Hoffmann and Parsons (1989a, b). The results agree with this prediction.
Barros
A R
AR
Departamento de Biología Funcional, Universidad de Oviedo, Spain.
Sierra
L M
LM
Comendador
M A
MA
D000171:Acrolein / Q000494:pharmacology*; D000818:Animals; D004331:Drosophila melanogaster / Q000187:drug effects / Q000235:genetics*; D004734:Energy Metabolism / Q000187:drug effects / Q000235:genetics; D008957:Models, Genetic; D009154:Mutation / Q000235:genetics; D010101:Oxygen Consumption / Q000187:drug effects / Q000235:genetics*
D000171:Acrolein