[Digestive manifestations of common variable immunodeficiency].
We present 4 cases of common variable immunodeficiency with main digestive clinical manifestations. In all four cases chronic diarrhea with intestinal malabsorption predominated, as well as the presence lymphoid nodular hyperplasia; in one case Giardia infestation could be identified; one patient also presented chronic pancreatitis, or recurrent aphthous stomatitis and active chronic hepatitis; sideroblastic anemia could be observed in another patient. All patients had favorable evolution during follow-up which lasted at least 14 months in substitutive treatment with immunoglobulins. One of our patients presented an elevated number of suppressor T lymphocytes, with inversion of the T helper/T suppressor ratio which improved with cimetidine treatment.
Estrada Pérez
V
V
Servicio de Medicina Interna III, Hospital Clínico de San Carlos, Universidad Complutense, Madrid.
Pérez de la Serna
J
J
García Paredes
J
J
Cortés León
M
M
Gutiérrez Marcos
F M
FM
Estrada Sáiz
R V
RV
D000328:Adult; D004066:Digestive System Diseases / Q000209:etiology*; D005260:Female; D005873:Giardiasis / Q000209:etiology; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000150:complications*; D008206:Lymphatic Diseases / Q000209:etiology; D008286:Malabsorption Syndromes / Q000209:etiology; D008297:Male
Manifestaciones digestivas de la inmunodeficiencia común variable.