title: Reduced concentration of secretory IgA indicates changes of local immunity in children with adenoid hyperplasia and secretory otitis media.
abstract: Children with adenoid hyperplasia and secretory otitis media show significantly lower immunoglobulin A (sIgA) concentrations in their saliva compared to matched controls. Salivary albumin and cortisol levels do not differ in both groups. Changes in local immunity, dilution or stress as possible factors for the reduction of sIgA concentrations are discussed.
authors.affiliation: HNO-Klinik, Universität Düsseldorf, BRD.
authors.forename: M
authors.initials: M
authors.lastname: Hess
authors.forename: J
authors.initials: J
authors.lastname: Kugler
authors.forename: D
authors.initials: D
authors.lastname: Haake
authors.forename: J
authors.initials: J
authors.lastname: Lamprecht
mesh_terms: D000234:Adenoids / Q000276:immunology*; D000418:Albumins / Q000032:analysis; D016022:Case-Control Studies; D002648:Child; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis; D006965:Hyperplasia; D007071:Immunoglobulin A, Secretory / Q000032:analysis*; D008297:Male; D015508:Nasal Obstruction / Q000276:immunology; D010034:Otitis Media with Effusion / Q000276:immunology*; D012463:Saliva / Q000737:chemistry / Q000276:immunology*; D012471:Salivary Proteins and Peptides / Q000032:analysis
chemical_list: D000418:Albumins; D007071:Immunoglobulin A, Secretory; D012471:Salivary Proteins and Peptides; D006854:Hydrocortisone