Identification of 4-methoxybenzoyl-N-glycine in urine by gas chromatography/mass spectrometry.
An unusual metabolite was detected in the urine of two children with neurological dysfunctions of unclear aetiology by using gas chromatography/mass spectrometry (GC/MS). On the basis of the analysis of its fragmentation pathways, synthesis of tentative compound and its GC/MS analysis it was stated that the unknown metabolite is 4-methoxybenzoyl-N-glycine.
Antoshechkin
A G
AG
Laboratory of Inherited Metabolic Defects, Institute of Molecular Genetics, USSR Academy of Sciences, Moscow.
Seriogina
I A
IA
Maximova
L A
LA
Tatur VYu
D000840:Anisoles / Q000652:urine*; D002648:Child; D002675:Child, Preschool; D008401:Gas Chromatography-Mass Spectrometry; D005998:Glycine / Q000031:analogs & derivatives* / Q000652:urine; D006626:Hippurates; D006801:Humans; D007223:Infant; D008607:Intellectual Disability / Q000652:urine; D008661:Metabolism, Inborn Errors / Q000652:urine*; D009422:Nervous System Diseases / Q000652:urine
D000840:Anisoles; D006626:Hippurates; C072836:4-methyoxybenzoyl-N-glycine; D005998:Glycine