title: Cause of closed suction drainage tube obstruction and its prevention using a tube coated on the inside with a silicone gel drug delivery system.
abstract: In experimental and clinical studies we showed that obstruction of closed suction drainage tubes is often caused by clots. To prevent this we describe a tube coated on the inside with a silicone gel drug delivery system, which releases anticoagulant drugs. It prevents coagulation and liquefies blood clots present in the tube. This device should thus find application as a tube for continuous suction drainage systems.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Hirosaki University School of Medicine, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Sawada
authors.forename: H
authors.initials: H
authors.lastname: Kudo
authors.forename: K
authors.initials: K
authors.lastname: Sone
mesh_terms: D000925:Anticoagulants / Q000008:administration & dosage; D001777:Blood Coagulation / Q000187:drug effects*; D004322:Drainage / Q000295:instrumentation*; D016503:Drug Delivery Systems / Q000295:instrumentation*; D004868:Equipment Failure; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D012828:Silicones; D013997:Time Factors
chemical_list: D000925:Anticoagulants; D012828:Silicones; D005340:Fibrinogen