Increment of brain temporal perfusion during auditory stimulation. Preliminary study with technetium-99m HMPAO SPET.
A study on the dynamic exploration of the auditory pathway is presented, in which technetium-99m hexamethylpropylene amine oxime single-photon emission computed tomography (SPET) was used in volunteers with normal hearing. Changes in 99mTc-HMPAO distribution were calculated using a region of interest/whole-brain count ratio. The results showed a temporal perfusion increment of 17% (right) and 19% (left) during tonal supraliminar stimulation, which was significantly different from the control ROI. Sensitivity tests for the method were requested before any clinical application.
Le Scao
Y
Y
Department of Oto-Rhino-Laringology, Centre Hospitalo-universitaire de Tours, France.
Baulieu
J L
JL
Robier
A
A
Pourcelot
L
L
Beutter
P
P
D000161:Acoustic Stimulation; D001303:Auditory Cortex / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000502:physiology; D002560:Cerebrovascular Circulation / Q000502:physiology*; D006801:Humans; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime