Clostridium sordellii in diarrhoeal stools, its medical significance.
The 3 Clostridium sordellii strains were isolated from the immunocompromised patient's infected-stool. These isolates were studied in detail. One strain revealed the weakly positive cytotoxin with human diploid fibroblasts whereas the other strain showed induration and edema (VP factor). All strains were confirmed to be Cl.sordellii with specific Cl.sordellii antitoxin. None of them harboured enterotoxin but they were very sensitive to imipenem cefoxitin, moderately sensitive to moxalactam. The role of probable pathophysiologic infection in the human bowel of these isolates are also discussed in this article.
Butra
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Department of Medical Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Vichivanives
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P
D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D003013:Clostridium / Q000187:drug effects / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000382:microbiology*; D003967:Diarrhea / Q000382:microbiology*; D005243:Feces / Q000382:microbiology*; D005260:Female; D006801:Humans; D007108:Immune Tolerance; D008297:Male; D008826:Microbial Sensitivity Tests
D000900:Anti-Bacterial Agents