title: Hypoglycemic and antihyperglycemic effect of leaves of Vinca rosea linn.
abstract: Oral administration of water fraction of alcoholic extract of leaves of Vinca rosea (fam. apocynaeceae) led to marked lowering of blood glucose level in normal and streptozotocin induced diabetic rats. The hypoglycemic effect of the fraction was comparable with that of tolbutamide.
authors.affiliation: Biometry Research Unit, Indian Statistical Institute, Calcutta.
authors.forename: R R
authors.initials: RR
authors.lastname: Chattopadhyay
authors.forename: S K
authors.initials: SK
authors.lastname: Sarkar
authors.forename: S
authors.initials: S
authors.lastname: Ganguly
authors.forename: R N
authors.initials: RN
authors.lastname: Banerjee
authors.forename: T K
authors.initials: TK
authors.lastname: Basu
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001786:Blood Glucose / Q000187:drug effects* / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy; D004347:Drug Interactions; D005260:Female; D005947:Glucose / Q000008:administration & dosage / Q000378:metabolism; D005951:Glucose Tolerance Test; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D007328:Insulin / Q000494:pharmacology; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin; D010936:Plant Extracts; D005947:Glucose