Pathomorphological changes in calf erythrocytes during phenylhydrazine-induced acute hemolytic anaemia.
In acute hemolytic anaemia of calves induced with phenylhydrazine-hydrochloride, accentuated degenerative changes in circulating erythrocytes occurred on the 5th d post-injection. Marked anisocytosis and poikilocytosis were observed. Crenated cells, acanthocytes (star-shaped cells), dacrocytes (tear drop cells), bite cells, and schistocytes predominated. Heinz bodies were the cytoplasmic hallmark of hemolytic anaemia. The regenerative nature of anaemia was evidenced by early appearance of reticulocytes in peripheral blood.
Sharma
M L
ML
Department of Medicine, College of Veterinary Science and Animal Husbandry, Jabalpur, M.P., India.
Soni
J L
JL
Datta
K
K
D000208:Acute Disease; D000743:Anemia, Hemolytic / Q000097:blood / Q000662:veterinary*; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000097:blood*; D004195:Disease Models, Animal; D004912:Erythrocytes / Q000473:pathology*; D008297:Male; D010659:Phenylhydrazines
D010659:Phenylhydrazines; C030299:phenylhydrazine