[The effect of copper and insulin on nucleic acid and protein synthesis in Tetrahymena pyriformis cells under different functional conditions].
The effect of copper ions and insulin on the rate of DNA, RNA and protein synthesis, and on the growth dynamics of Tetrahymena pyriformis cells, and also joint action of Cu2+ and insulin on these processes has been investigated. The effect of Cu2+ after 6-fold action of heat shock (34 degrees C) on the cell culture has been studied. The results obtained indicate that significant reconstructions of the infusoria cell functioning conditions caused by various reasons re of great importance in the adaptation mechanisms to such stress factors as heavy metals.
Usenko
E V
EV
Bozhkov
A I
AI
Kaliman
P A
PA
D000818:Animals; D003300:Copper / Q000494:pharmacology*; D016054:DNA, Protozoan / Q000096:biosynthesis / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D006360:Heat-Shock Proteins / Q000096:biosynthesis / Q000187:drug effects; D007328:Insulin / Q000494:pharmacology*; D015800:Protozoan Proteins / Q000096:biosynthesis / Q000187:drug effects*; D016053:RNA, Protozoan / Q000096:biosynthesis / Q000187:drug effects*; D013696:Temperature; D013769:Tetrahymena pyriformis / Q000187:drug effects* / Q000378:metabolism
D016054:DNA, Protozoan; D006360:Heat-Shock Proteins; D007328:Insulin; D015800:Protozoan Proteins; D016053:RNA, Protozoan; D003300:Copper
Vliianie medi i insulina na sintez nukleinovykh kislot i belka v kletka Tetrahymena pyriformis, nakhodiashchikhsia v razlichnykh funktsional'nykh sostoianiiakh.