Genetic polymorphism of alpha-2-HS-glycoprotein in a Spanish population.
The genetic polymorphism of alpha-2-HS-glycoprotein (AHSG) was analyzed in 489 unrelated individuals living in Madrid (central Spain), by isoelectric focusing in miniaturized polyacrylamide gels followed by immunoblotting. The allele frequencies were estimated to be 0.7147 and 0.2771 for AHSG*1 and AHSG*2, respectively. In addition to the common alleles, 3 rare variants (AHSG*3, AHSG*10 and AHSG*11) have been found in this study.
Alonso
A
A
Sección de Biología, Instituto Nacional de Toxicología, Madrid, España.
Weidinger
S
S
Visedo
G
G
Sancho
M
M
Fernández-Piqueras
J
J
D000483:Alleles; D001798:Blood Proteins / Q000235:genetics*; D005787:Gene Frequency / Q000235:genetics*; D006801:Humans; D015151:Immunoblotting; D007525:Isoelectric Focusing; D010641:Phenotype; D011110:Polymorphism, Genetic / Q000235:genetics*; D013030:Spain; D060749:alpha-2-HS-Glycoprotein
C556354:AHSG protein, human; D001798:Blood Proteins; D060749:alpha-2-HS-Glycoprotein