[Use of enterosorption for correction of dyslipoproteinemias in patients with ischemic heart disease in geriatric practice].
Sixty patients with coronary heart disease, stable angina pectoris of functional class II and III and dislipoproteinemia (cholesterol greater than 6.5 mmol/l, triglycerides greater than 2.0 mmol/l, the atherogenic index greater than 3.5) were assigned to two groups. 40 patients received enterosorbent (high-porous, small-spherical fraction of CKH carbon). 20 control subjects were treated with placebo. The patients age ranged from 60 to 74. The treatment course lasted for 4 weeks. Evaluation of the treatment results showed that total cholesterol dropped by 20%, triglycerides by 27%, apoB by 32%, apoB-containing lipoproteins by 20%; there were positive changes in circulation, clinical status (in 60% of cases), exercise tolerance (by 12%). Control patients did not present any noticeable shifts. Thus, enterosorption proved an effective modality of dyslipoproteinemia correction in coronary patients of advanced age.
Korkushko
O V
OV
Bogatskaia
L N
LN
Novikova
S N
SN
Kotko
D N
DN
Nikolaev
V G
VG
Shcherbitskaia
E V
EV
D000368:Aged; D002606:Charcoal / Q000008:administration & dosage; D008078:Cholesterol, LDL / Q000097:blood*; D015243:Cholesterol, VLDL / Q000097:blood*; D003327:Coronary Disease / Q000097:blood*; D016061:Enterosorption; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010919:Placebos
D008078:Cholesterol, LDL; D015243:Cholesterol, VLDL; D010919:Placebos; C029814:SKN hemosorbents; D002606:Charcoal
Ispol'zovanie énterosorbtsii s tsel'iu korrektsii dislipoproteidemiĭ u bol'nykh IBS v geriatricheskoĭ praktike.