title: Association of a thyrotropin-secreting pituitary adenoma and a thyroid follicular carcinoma.
abstract: The different factors involved as etiological agents in thyroid cancer have in common long term thyroid follicle stimulation. On this base, a patient with a TSH-producing pituitary adenoma could be at high risk for developing thyroid cancer. A patient consulting for a single thyroid nodule was studied in our unit. He was diagnosed as having a TSH-producing pituitary adenoma and the Thyroid nodule was shown to be a follicular carcinoma following removed. We speculate that elevated TSH levels could have contributed to neoplastic transformation of the thyroid in this patient.
authors.affiliation: Unidad de Endocrinologia y Nutricion, Hospital Ntra Sra de Sonsoles, Avila, Spain.
authors.forename: A L
authors.initials: AL
authors.lastname: Calle-Pascual
authors.forename: E
authors.initials: E
authors.lastname: Yuste
authors.forename: P
authors.initials: P
authors.lastname: Martin
authors.forename: T
authors.initials: T
authors.lastname: Aramendi
authors.forename: M L
authors.initials: ML
authors.lastname: Garcia-Mauriño
authors.forename: J
authors.initials: J
authors.lastname: Argente
authors.forename: M J
authors.initials: MJ
authors.lastname: Catalan
authors.forename: J
authors.initials: J
authors.lastname: Uria
authors.forename: J A
authors.initials: JA
authors.lastname: Cabranes
authors.forename: A L
authors.initials: AL
authors.lastname: Charro
mesh_terms: D000230:Adenocarcinoma / Q000150:complications* / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D000236:Adenoma / Q000150:complications* / Q000473:pathology; D001921:Brain / Q000000981:diagnostic imaging; D002230:Carbidopa / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D013006:Growth Hormone / Q000494:pharmacology; D013007:Growth Hormone-Releasing Hormone / Q000494:pharmacology; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D007328:Insulin / Q000494:pharmacology; D007980:Levodopa / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D011388:Prolactin / Q000097:blood; D011863:Radioimmunoassay; D013964:Thyroid Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D013972:Thyrotropin / Q000097:blood; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology; D013974:Thyroxine / Q000097:blood / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed; D014284:Triiodothyronine / Q000097:blood
chemical_list: D007328:Insulin; D014284:Triiodothyronine; D007980:Levodopa; D013973:Thyrotropin-Releasing Hormone; D011388:Prolactin; D013972:Thyrotropin; D013006:Growth Hormone; D013007:Growth Hormone-Releasing Hormone; D002230:Carbidopa; D013974:Thyroxine; D006854:Hydrocortisone