[Effects of antidepressive agents on tolerance of hypoxia and physical exercise].
In experiments on mice and rats we studied the influence of antidepressants on hypoxic and physical tolerance. The antidepressants pyrazidol, azaphen, imipramine and moclobemide as well as the nootropic drug piracetam prolonged the life of animals in conditions of hypoxic and hemic hypoxia and increased the survival rate of rats in circulatory hypoxia. In experiments on mice antidepressants increased also the time of swimming.
Andreeva
N I
NI
Golovina
S M
SM
Parshin
V A
VA
Mashkovskiĭ
M D
MD
D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D000929:Antidepressive Agents, Tricyclic / Q000494:pharmacology; D001549:Benzamides / Q000494:pharmacology; D002227:Carbazoles / Q000494:pharmacology; D002243:Carbolines / Q000494:pharmacology; D005260:Female; D000860:Hypoxia; D007099:Imipramine / Q000494:pharmacology; D008297:Male; D051379:Mice; D020912:Moclobemide; D008996:Monoamine Oxidase Inhibitors / Q000494:pharmacology; D010078:Oxazines / Q000494:pharmacology; D005082:Physical Exertion; D010889:Piracetam / Q000494:pharmacology; D051381:Rats; D013550:Swimming
D000928:Antidepressive Agents; D000929:Antidepressive Agents, Tricyclic; D001549:Benzamides; D002227:Carbazoles; D002243:Carbolines; D008996:Monoamine Oxidase Inhibitors; D010078:Oxazines; C100161:azaphen; C027473:metralindole; D007099:Imipramine; D020912:Moclobemide; C009830:pirlindole; D010889:Piracetam
Vliianie antidepressantov na vynoslivost' k gipoksii i fizicheskoĭ nagruzke.