title: Estimation of fetal lung maturity by assessment of lamellar body particle concentration.
abstract: The concentration of lamellar bodies expressed as the optical density at 700 nm in amniotic fluid samples was calculated after centrifugation of the samples to obtain the lamellar bodies in a relatively pure form. The lamellar body concentrations obtained were compared with lecithin-sphingomyelin (L/S) ratios from the same samples. The advantages of the method compared with the L/S ratio are discussed as is the dependence on total volume that the method shares with all other procedures which depend on the measurement of a single concentration.
authors.affiliation: Clinical Chemistry Laboratory, University Hospital Maastricht, The Netherlands.
authors.forename: B K
authors.initials: BK
authors.lastname: van Kreel
mesh_terms: D000653:Amniotic Fluid / Q000737:chemistry*; D005325:Fetal Organ Maturity / Q000502:physiology; D006801:Humans; D008168:Lung / Q000196:embryology* / Q000648:ultrastructure; D010713:Phosphatidylcholines / Q000032:analysis; D015203:Reproducibility of Results; D013109:Sphingomyelins / Q000032:analysis; D014461:Ultracentrifugation
chemical_list: D010713:Phosphatidylcholines; D013109:Sphingomyelins