title: Seasonal changes in plasma concentrations of gonadotropins and in the responsiveness of the pituitary and testis to GnRH in a desert rodent, the sand rat (Psammomys obesus).
abstract: The male sand rat (Psammomys obesus), captured alive in the Sahara desert in the area of Béni-Abbès (Algeria), exhibited seasonal changes in plasma concentrations of LH, characterized by an increase in early summer. Administration of a standard dose of GnRH (200 ng/100 g body weight) failed to elicit significant season-dependent changes in LH release, whereas the increase in plasma testosterone was maximum in June-July and quite small between November and March-April. The present results suggest that the summer seasonal onset of the testicular endocrine activity of the sand rat is due to increases both in LH release and in testis sensitivity to gonadotropin.
authors.affiliation: Université (USTHB) d'Alger, Laboratoire d'Endocrinologie et Ecophysiologie Animale, Alger, Algérie.
authors.forename: F
authors.initials: F
authors.lastname: Khammar
authors.forename: R
authors.initials: R
authors.lastname: Brudieux
mesh_terms: D000818:Animals; D005640:Follicle Stimulating Hormone / Q000097:blood; D005849:Gerbillinae / Q000097:blood*; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology*; D007986:Luteinizing Hormone / Q000097:blood*; D008297:Male; D009929:Organ Size; D010902:Pituitary Gland / Q000187:drug effects / Q000502:physiology*; D012621:Seasons; D012669:Seminal Vesicles / Q000033:anatomy & histology; D013737:Testis / Q000033:anatomy & histology / Q000187:drug effects / Q000502:physiology*; D013739:Testosterone / Q000097:blood
chemical_list: D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone