Cytotoxicity of 3-hydroxykynurenine: implications for CNS damage in neonatal vitamin B-6 deficiency.
Eastman
C L
CL
Department of Environmental Health Sciences, Johns Hopkins University School of Hygiene and Public Health, Baltimore, Maryland 21205.
Guilarte
T R
TR
D000818:Animals; D000831:Animals, Newborn / Q000378:metabolism; D000975:Antioxidants / Q000494:pharmacology; D001921:Brain / Q000201:enzymology / Q000254:growth & development; D001923:Brain Chemistry; D016923:Cell Death / Q000187:drug effects; D006822:Hybrid Cells / Q000187:drug effects; D006867:Hydrolases / Q000378:metabolism; D007737:Kynurenine / Q000031:analogs & derivatives* / Q000633:toxicity; D051379:Mice; D009447:Neuroblastoma / Q000473:pathology; D010084:Oxidation-Reduction; D011736:Pyridoxine / Q000502:physiology; D012160:Retina / Q000166:cytology; D012640:Seizures / Q000209:etiology; D026681:Vitamin B 6 Deficiency / Q000150:complications / Q000378:metabolism*
D000975:Antioxidants; C005045:3-hydroxykynurenine; D007737:Kynurenine; D006867:Hydrolases; C021480:kynureninase; D011736:Pyridoxine