title: Activation of a specific vestibulo-olivary pathway by centripetal acceleration in rat.
abstract: Unanesthetized Long-Evans (pigmented) rats were subjected to 2.0 G centripetal acceleration for 90 min. Immunohistochemical analysis, using a polyclonal antibody for Fos, revealed a distinct pattern of neuronal activation in the off-axis animals in the dorsomedial cell column (DMCC) of the inferior olivary nucleus. These results are consistent with previous anatomical evidence and indicate that the DMCC is an important component in an otolith-olivocerebellar circuit which may help to define an internal spatial reference.
authors.affiliation: Department of Veterinary Biology, University of Minnesota, St. Paul 55108.
authors.forename: G D
authors.initials: GD
authors.lastname: Kaufman
authors.forename: J H
authors.initials: JH
authors.lastname: Anderson
authors.forename: A
authors.initials: A
authors.lastname: Beitz
mesh_terms: D000054:Acceleration; D000818:Animals; D007150:Immunohistochemistry; D009434:Neural Pathways / Q000502:physiology; D009847:Olivary Nucleus / Q000502:physiology*; D016760:Proto-Oncogene Proteins c-fos / Q000276:immunology; D051381:Rats; D012399:Rotation; D014722:Vestibule, Labyrinth / Q000502:physiology*
chemical_list: D016760:Proto-Oncogene Proteins c-fos