title: Experience with anatomical correction of transposition of the great arteries (TGA).
abstract: During the past seven years, 102 patients with TGA have been operated on using the switch operation. Overall early mortality was 5.9%, late mortality 2.%. Sixty-three newborns had an intact septum and were corrected between the 3th and 35th day after birth, 39 had a ventricular septal defect and/or associated anomalies. All operations were carried out under ECC and deep hypothermia. Myocardial function was recorded intraoperatively by using sonomicrometry. The data demonstrate that adaptation of the left ventricle to the new load conditions should be supported by drugs providing inotropic stimulation and afterload reduction. Mean follow-up time is 32.5 months, no rhythm problems have been recorded during that period, a few children revealed trivial pulmonary or aortic valve stenosis and/or incompetence. The switch operation permits good early results for newborns with TGA and intact septum and TGA with VSD. A decade has to pass in order to judge the long-term results.
authors.affiliation: Department of Cardiac and Vascular Surgery, German Heart Center, Munich.
authors.forename: H
authors.initials: H
authors.lastname: Meisner
authors.forename: S
authors.initials: S
authors.lastname: Paek
authors.forename: W
authors.initials: W
authors.lastname: Heimisch
authors.forename: R
authors.initials: R
authors.lastname: Kunkel
authors.forename: H P
authors.initials: HP
authors.lastname: Lorenz
authors.forename: F
authors.initials: F
authors.lastname: Sebening
mesh_terms: D005500:Follow-Up Studies; D006345:Heart Septal Defects, Ventricular / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D013997:Time Factors; D014188:Transposition of Great Vessels / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D016277:Ventricular Function, Left / Q000502:physiology