title: Isolation and identification of chicken infectious anemia virus in Brazil.
abstract: Seven chicken infectious anemia virus (CIAV) isolates were obtained from seven broiler flocks with poor performance in two states of Brazil. All isolates induced thymus atrophy, bone-marrow aplasia, and low hematocrit values when inoculated into 1-day-old susceptible chicks. The CIAV isolates were resistant to treatment with chloroform and were able to pass through 50-nm-pore-size filters. CIAV-specific antigens could be demonstrated in tissues of experimentally infected chicks using a monoclonal antibody specific for CIAV. These characteristics of the virus and the virus-induced lesions demonstrate that CIAV is present in Brazil and that the virus is associated with production problems.
authors.affiliation: Centro Nacional de Pesquisas de Suinos e Aves (CNPSA), Agropecuaria (EMBRAPA), Concordia, SC, Brazil.
authors.forename: L
authors.initials: L
authors.lastname: Brentano
authors.forename: N
authors.initials: N
authors.lastname: Mores
authors.forename: I
authors.initials: I
authors.lastname: Wentz
authors.forename: D
authors.initials: D
authors.lastname: Chandratilleke
authors.forename: K A
authors.initials: KA
authors.lastname: Schat
mesh_terms: D000740:Anemia / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D001853:Bone Marrow / Q000473:pathology; D001938:Brazil; D002460:Cell Line; D002645:Chickens; D004267:DNA Viruses / Q000302:isolation & purification* / Q000648:ultrastructure; D008854:Microscopy, Electron; D011201:Poultry Diseases / Q000382:microbiology* / Q000473:pathology; D012692:Serial Passage; D013154:Spleen / Q000382:microbiology / Q000473:pathology; D013950:Thymus Gland / Q000382:microbiology / Q000473:pathology; D014777:Virus Diseases / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*
chemical_list: D000956:Antigens, Viral