title: [Focal hepato-splenic mycosis caused by Trichosporon beigelii in a patient with acute leukemia].
abstract: We report a case of infection produced by Trichosporon beigelii in a patient with acute leukaemia. In spite of treatment with amphotericin B the patient died and the necropsy studies showed only involvement of liver and spleen without disseminated infection. Focal hepatosplenic fungal infection has been recognized with increasing frequency in recent years as a serious complication in immunosuppressed patients. Usually it is produced by Candida spp and this is the first case described in the literature due to the newly recognized fungus T. beigelii.
authors.affiliation: Servicio de Hematología y Hemoterapia, Hospital Severo Ochoa, Leganés, Madrid.
authors.forename: A
authors.initials: A
authors.lastname: Alegre
authors.forename: M
authors.initials: M
authors.lastname: Algora
authors.forename: M A
authors.initials: MA
authors.lastname: Peñalver
authors.forename: M L
authors.initials: ML
authors.lastname: Llanos
authors.forename: C
authors.initials: C
authors.lastname: Pérez-Pons
authors.forename: I
authors.initials: I
authors.lastname: García Plaza
authors.forename: M
authors.initials: M
authors.lastname: Lozano
authors.forename: B
authors.initials: B
authors.lastname: Padilla
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use; D003561:Cytarabine / Q000008:administration & dosage / Q000009:adverse effects; D003630:Daunorubicin / Q000008:administration & dosage / Q000009:adverse effects; D004198:Disease Susceptibility; D006505:Hepatitis / Q000150:complications* / Q000382:microbiology; D006801:Humans; D016867:Immunocompromised Host; D015473:Leukemia, Promyelocytic, Acute / Q000150:complications* / Q000188:drug therapy; D008297:Male; D009181:Mycoses / Q000150:complications*; D009894:Opportunistic Infections / Q000150:complications*; D013158:Splenic Diseases / Q000150:complications* / Q000382:microbiology; D014250:Trichosporon
chemical_list: D003561:Cytarabine; D003630:Daunorubicin
vernacular_title: Micosis hepatoesplénica focal por Trichosporon beigelii en un paciente con leucemia aguda.