title: Enhancement of amniotic fluid cell growth for genetic amniocentesis.
abstract: The last two decades have witnessed a logarithmic growth in demand for prenatal diagnosis of human disease through amniocentesis. Consequently, culture turn-around-time has become the major concern of all those who are primary care providers for patients seeking help. We report a rapid method for obtaining cytogenetic results from amniocytes as early as 5 days. Early tapping and reducing the turn-around-time during cytogenetic analysis may provide an alternative to chorionic villi sampling.
authors.affiliation: Division of Genetics, Long Island College Hospital, SUNY Health Science Center, Brooklyn.
authors.forename: T
authors.initials: T
authors.lastname: Mathews
authors.forename: R S
authors.initials: RS
authors.lastname: Verma
mesh_terms: D000649:Amniocentesis / Q000379:methods*; D000653:Amniotic Fluid / Q000166:cytology*; D002455:Cell Division / Q000502:physiology; D002478:Cells, Cultured; D002985:Clinical Protocols; D005260:Female; D006801:Humans; D007621:Karyotyping / Q000379:methods; D011247:Pregnancy; D013997:Time Factors