title: Ketorolac in acute headache management.
abstract: Twelve patients presenting to an emergency department in headache crisis were treated with Ketorolac tromethamine 60 mg. intramuscularly. All improved sufficiently to require no further emergent treatment. There was statistically significant improvement on all segments of the short form McGill Pain Questionnaire. This open label trial suggests that Ketorolac Tromethamine may be a useful agent in the treatment of headache crisis, and a controlled study to examine this is warranted.
authors.affiliation: Dept. of Neurology, Medical University of South Carolina, Charleston 29425.
authors.forename: R N
authors.initials: RN
authors.lastname: Harden
authors.forename: T D
authors.initials: TD
authors.lastname: Carter
authors.forename: C S
authors.initials: CS
authors.lastname: Gilman
authors.forename: A J
authors.initials: AJ
authors.lastname: Gross
authors.forename: J R
authors.initials: JR
authors.lastname: Peters
mesh_terms: D000208:Acute Disease; D000700:Analgesics / Q000627:therapeutic use*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D006261:Headache / Q000188:drug therapy*; D006801:Humans; D020911:Ketorolac Tromethamine; D014046:Tolmetin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D014325:Tromethamine / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D014325:Tromethamine; D020911:Ketorolac Tromethamine; D014046:Tolmetin