title: [Current status of Clostridium difficile: recent advances in diagnostic materials and treatment of colitis and diarrheas associated with antibiotic therapy].
abstract: Clostridium difficile infection covers several clinical pictures which have been identified only recently. The majority are based upon imbalance in the intestinal ecosystem. Major advances in recent years concerning this type of infection have involved: a) better knowledge of pathophysiological mechanisms, in particular the demonstration of a 2nd toxin, essential to the understanding of C. difficile infections; b) better codification of the management of these disorders. This is aimed today at treating the infection while maintaining the balance of the intestinal ecosystem.
authors.affiliation: Dept. of Gastroenterology, Boston University Medical Center, Massachusetts.
authors.forename: M
authors.initials: M
authors.lastname: Dru
mesh_terms: D015984:Causality; D002985:Clinical Protocols; D003082:Colectomy; D004761:Enterocolitis, Pseudomembranous / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D005260:Female; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D012008:Recurrence; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D008795:Metronidazole; D014640:Vancomycin
vernacular_title: Mise à jour sur Clostridium difficile: progrès récents en matière de diagnostic et de traitement des colites et diarrhées associées à l'antibiothérapie.