Influence of prolonged physical exercise on the erythropoietin concentration in blood.
Erythropoietin (EPO) and red blood cells were studied in 15 well-trained men before and several times after a marathon run. Changes in red blood cells reflected changes of plasma volume. Immediately after the run, red blood cells were increased due to haemoconcentration, whereas 31 h later the values were decreased due to haemodilution. The EPO concentration was increased 3 h, and more impressive 31 h, after the run. This long-lasting increase in EPO concentration after the marathon run would seem to be responsible for the increased red blood cell mass in long distance runners.
Schwandt
H J
HJ
Institut für Leistungsmedizin, Abteilung Sportphysiologie, Berlin, Federal Republic of Germany.
Heyduck
B
B
Gunga
H C
HC
Röcker
L
L
D000328:Adult; D004906:Erythrocyte Count; D004921:Erythropoietin / Q000097:blood*; D015444:Exercise / Q000502:physiology*; D006400:Hematocrit; D006438:Hemodilution; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D008297:Male; D010953:Plasma Volume; D012156:Reticulocytes / Q000166:cytology; D012420:Running; D013997:Time Factors
D006454:Hemoglobins; D004921:Erythropoietin