title: Plasma histamine levels in laminitic horses and in horses treated with a corticosteroid.
abstract: In seven sound horses histamine plasma levels were evaluated by means of a radioenzymatic method using the enzyme histamine-N-methyltransferase (mean = 4.46 nmol/l, SD = 1.55 nmol/l). Histamine levels of laminitic horses were significantly higher (n = 11; mean = 12.46 nmol/l, SD = 3.24 nmol/l). In three sound horses plasma histamine levels were determined over a two week period following a double administration of 10 mg dexamethasone-21-isonicotinate/100 kg body weight. Histamine levels remained within the range of sound control horses.
authors.affiliation: Clinic of Orthopaedics in Ungulates, University of Veterinary Medicine, Vienna, Austria.
authors.forename: R
authors.initials: R
authors.lastname: Rautschka
authors.forename: C
authors.initials: C
authors.lastname: Stanek
authors.forename: P F
authors.initials: PF
authors.lastname: Knezevic
mesh_terms: D000818:Animals; D003907:Dexamethasone / Q000494:pharmacology*; D005260:Female; D005534:Foot Diseases / Q000097:blood / Q000662:veterinary; D006632:Histamine / Q000097:blood*; D006724:Hoof and Claw / Q000473:pathology*; D006734:Horse Diseases / Q000097:blood*; D006736:Horses / Q000097:blood*; D008297:Male
chemical_list: D003907:Dexamethasone; D006632:Histamine