title: Study on rat-rat hybridoma technique and production of rat monoclonal antibodies against HIV and HBsAg.
abstract: The rat-rat hybridoma technique has some definite advantages in the three systems (mouse, rat or human system) currently utilized for monoclonal antibody production. The study on rat-rat hybridoma technique and its application to the productions of monoclonal antibodies against human immunodeficiency virus (HIV) and hepatitis B virus surface antigen (HBsAg) are described as examples in this paper.
authors.affiliation: Department of Cell Biology, Beijing Institute for Cancer Research, China.
authors.forename: J C
authors.initials: JC
authors.lastname: Fang
authors.forename: M
authors.initials: M
authors.lastname: Bodeus
authors.forename: G
authors.initials: G
authors.lastname: Burtonboy
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis* / Q000276:immunology / Q000302:isolation & purification; D002459:Cell Fusion; D002999:Clone Cells; D005260:Female; D006678:HIV / Q000276:immunology*; D006514:Hepatitis B Surface Antigens / Q000276:immunology*; D006825:Hybridomas; D007114:Immunization; D008297:Male; D051381:Rats
chemical_list: D000911:Antibodies, Monoclonal; D006514:Hepatitis B Surface Antigens