title: [Antiviral therapy with recombinant alpha-interferon in chronic B virus hepatitis].
abstract: Two patients with chronic Hepatitis B virus infection were treated with recombinant alpha-interferon. A positive response with seroconversion from HbeAg to Anti HBe and loss of HBsAg and appearance of Anti-HBs was obtained in one patient. Clinical characteristics and factors that may influence the response are discussed in the light of a review of the literature.
authors.affiliation: Centro de Gastroenterología, Hospital Clínico de la Universidad de Chile, Santiago de Chile.
authors.forename: J
authors.initials: J
authors.lastname: Brahm
authors.forename: C
authors.initials: C
authors.lastname: Hurtado
mesh_terms: D002908:Chronic Disease; D006509:Hepatitis B / Q000097:blood / Q000628:therapy*; D006511:Hepatitis B Antigens / Q000032:analysis; D006801:Humans; D007370:Interferon Type I / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D011994:Recombinant Proteins
chemical_list: D006511:Hepatitis B Antigens; D007370:Interferon Type I; D011994:Recombinant Proteins; D011241:Prednisone
vernacular_title: Terapia antiviral con interferon alfa recombinante en hepatitis crónica por virus B.