Pulmonary fibrosis associated with nabumetone.
A patient is described who developed a rapid onset of pulmonary fibrosis following treatment with a new non-steroidal anti-inflammatory drug, nabumetone. Resolution of symptoms, physical signs and radiographic changes followed drug withdrawal and steroid therapy.
Morice
A
A
Chest Medical Unit, Papworth Hospital, Cambs, UK.
Atherton
A
A
Gleeson
F
F
Stewart
S
S
D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D002074:Butanones / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D000077430:Nabumetone; D011239:Prednisolone / Q000627:therapeutic use; D011658:Pulmonary Fibrosis / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy; D011859:Radiography
D000894:Anti-Inflammatory Agents, Non-Steroidal; D002074:Butanones; D011239:Prednisolone; D000077430:Nabumetone