Guanine ribonucleotide depletion inhibits T cell activation.
Dayton
J S
JS
Department of Pharmacology, University of Michigan, Ann Arbor.
Turka
L A
LA
Thompson
C B
CB
Mitchell
B S
BS
D002453:Cell Cycle / Q000187:drug effects; D015870:Gene Expression / Q000187:drug effects; D006150:Guanine Nucleotides / Q000378:metabolism*; D006151:Guanosine / Q000494:pharmacology; D006160:Guanosine Triphosphate / Q000378:metabolism; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology; D066298:In Vitro Techniques; D008213:Lymphocyte Activation / Q000187:drug effects*; D012263:Ribonucleosides / Q000494:pharmacology*; D013601:T-Lymphocytes / Q000187:drug effects* / Q000276:immunology / Q000378:metabolism
D006150:Guanine Nucleotides; D007166:Immunosuppressive Agents; D012263:Ribonucleosides; D006151:Guanosine; C010052:mizoribine; D006160:Guanosine Triphosphate