[The heparin prophylaxis of gas exchange disorders in disseminated intravascular blood coagulation].
Altogether 35 patients operated on for gastric carcinoma were examined. In the postoperative period, a study was made of alterations in gas exchange function of the lungs parallel with the parameters of the hemostatic system. It has been established that in the early postoperative period, arterial hypoxemia was associated with the maximum tension of the functioning of the hemocoagulation system. Administration of heparin in a dose of 20,000 Units/day for 10 days led to a decrease of the period of arterial hypoxemia and reduction of its intensity. This is related to the blockade of intravascular blood coagulation. The heparin dose administered does not influence the plasma content of antithrombin-III and blood fibrinolytic activity.
Riabov
G A
GA
Pasechnik
I N
IN
Emtsov
Iu G
IuG
D000368:Aged; D000369:Aged, 80 and over; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000188:drug therapy / Q000503:physiopathology*; D006487:Hemostasis / Q000187:drug effects; D006493:Heparin / Q000008:administration & dosage*; D006801:Humans; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D011182:Postoperative Care; D011183:Postoperative Complications / Q000097:blood / Q000188:drug therapy / Q000503:physiopathology; D011659:Pulmonary Gas Exchange / Q000187:drug effects*; D013274:Stomach Neoplasms / Q000150:complications / Q000601:surgery; D013997:Time Factors
D006493:Heparin; D010100:Oxygen
Geparinprofilaktika narusheniĭ gazoobmena pri disseminirovannom vnutrisosudistom svertyvanii krovi.