title: Functional circulation time images in the diagnosis of cerebral lesions by angio CT.
abstract: An application of angio CT as an adjunct to contrast enhancement evaluation of cerebral lesions is presented. We performed rapid sequential scanning following intravenous bolus injection of an iodinated contrast medium, analyzed the time contrast curves and generated a functional circulation time image. This was accomplished by calculating on a pixel-by-pixel basis the first mathematical moment of the monitored time-density curves about injection time which corresponds to regional arm brain circulation time (rABCT). This method increased the rate of detection of cerebral lesions by contrast enhancement from 30 to 90%.
authors.affiliation: Institute of Clinical Neurology, University of Genoa, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Bartolini
authors.forename: B
authors.initials: B
authors.lastname: Gasparetto
authors.forename: C
authors.initials: C
authors.lastname: Albano
authors.forename: G
authors.initials: G
authors.lastname: Ajmar
authors.forename: R
authors.initials: R
authors.lastname: Amore
authors.forename: A
authors.initials: A
authors.lastname: Primavera
authors.forename: F
authors.initials: F
authors.lastname: Roncallo
mesh_terms: D001927:Brain Diseases / Q000000981:diagnostic imaging*; D002545:Brain Ischemia / Q000000981:diagnostic imaging; D001932:Brain Neoplasms / Q000000981:diagnostic imaging; D002533:Cerebral Angiography; D002544:Cerebral Infarction / Q000000981:diagnostic imaging; D002560:Cerebrovascular Circulation; D003287:Contrast Media; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging; D011856:Radiographic Image Enhancement / Q000379:methods*; D012016:Reference Values; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media