title: [Nonamyloid light-chain deposit disease. A report of 2 cases].
abstract: Two cases of non-amyloid light chain deposit disease (EDCL) which were diagnosed by liver biopsy are presented, and the recent literature is reviewed. This disease is a dysproteinemia which shares numerous clinical and pathological features with amyloidosis. A commentary is made on the differential diagnosis between both diseases. This disease must be suspected when the conventional histochemical and immunohistochemical stains for amyloid are negative. Immunohistochemical assays for kappa and lambda chains should then be performed.
authors.affiliation: Servicio de Anatomía Patológica, Hospital General de Castelló.
authors.forename: E
authors.initials: E
authors.lastname: Bernet Vegué
authors.forename: J M
authors.initials: JM
authors.lastname: Vera-Román
authors.forename: V
authors.initials: V
authors.lastname: Cortés Vizcaíno
authors.forename: J
authors.initials: J
authors.lastname: Uso Blasco
mesh_terms: D000328:Adult; D000368:Aged; D000682:Amyloid; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000175:diagnosis* / Q000473:pathology; D007147:Immunoglobulin Light Chains / Q000032:analysis; D007668:Kidney / Q000473:pathology; D008099:Liver / Q000473:pathology; D008297:Male
chemical_list: D000682:Amyloid; D007147:Immunoglobulin Light Chains
vernacular_title: Enfermedad por depósito de cadenas ligeras no-amiloides. Presentación de dos casos.