title: Immunoelectron microscopy of Fc receptors on the surface of clinical isolates of streptococci.
abstract: The distribution of Fc receptors on the surface of clinical isolates of streptococci was examined by immunoelectron microscopy. A unique two-layered ferritin tagging was observed on the surface of isolate MS-4 (group A). The spacing between the layers (10-40 nm) was narrower than that of the layered protein A (30-70 nm) on Staphylococcus aureus. Labeling on the other isolates, IP-28 (group A) and ES-21L (group C), showed similar rough layers, but the labeling were clearly different in thickness and density. The labeling on isolate IP-28 was also similar to that on strain AR1 (group A), reported previously, while the labeling on ES-21L was similar to that on protein G producing strain G148 (group G) in thickness. However, it was obviously thinner than that on IP-28 and AR1. These results strongly suggest that there are at least three distribution patterns of Fc receptors on streptococci, and these are distinct from that of protein A.
authors.affiliation: Department of Microbiology, Kawasaki Medical School, Okayama, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Yamada
authors.forename: A
authors.initials: A
authors.lastname: Matsumoto
authors.forename: K
authors.initials: K
authors.lastname: Uehira
authors.forename: T
authors.initials: T
authors.lastname: Suda
mesh_terms: D006386:Hemagglutination Tests; D007074:Immunoglobulin G / Q000378:metabolism; D016253:Microscopy, Immunoelectron; D011961:Receptors, Fc / Q000378:metabolism / Q000648:ultrastructure*; D013211:Staphylococcus aureus / Q000648:ultrastructure; D013297:Streptococcus pyogenes / Q000648:ultrastructure*
chemical_list: D007074:Immunoglobulin G; D011961:Receptors, Fc