title: Thrombotic microangiopathic nephropathy in scleroderma and lupus anticoagulant.
abstract: A 47-year-old woman with overlap scleroderma-polymyositis syndrome and positive circulating lupus anticoagulant developed scleroderma nephropathy, characterized by rapidly progressive renal failure caused by thrombotic microangiopathy with widespread thrombi in small arteries and glomeruli. The possible relationship between lupus anticoagulant and the development of thrombosis at the small renal vessels level with the triggering of the scleroderma crisis is discussed.
authors.affiliation: Servicio de Nefrologia, Hospital Ramón y Cajal, Madrid, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Quereda
authors.forename: J
authors.initials: J
authors.lastname: Pascual
authors.forename: A
authors.initials: A
authors.lastname: Pardo
authors.forename: F
authors.initials: F
authors.lastname: Mampaso
authors.forename: A
authors.initials: A
authors.lastname: Gonzalo
authors.forename: J
authors.initials: J
authors.lastname: Ortuño
mesh_terms: D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000150:complications* / Q000276:immunology / Q000473:pathology; D016682:Lupus Coagulation Inhibitor / Q000097:blood; D008875:Middle Aged; D009220:Myositis / Q000150:complications; D012595:Scleroderma, Systemic / Q000150:complications* / Q000276:immunology; D013577:Syndrome; D013927:Thrombosis / Q000150:complications* / Q000276:immunology / Q000473:pathology
chemical_list: D016682:Lupus Coagulation Inhibitor