Inhibition of vitamin B12-dependent methionine biosynthesis by chloroform and carbon tetrachloride.
Alston
T A
TA
Department of Anesthesia, Massachusetts General Hospital, Harvard Medical School, Boston 02114.
D013766:5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase / Q000037:antagonists & inhibitors*; D001975:Bromotrichloromethane / Q000494:pharmacology; D002251:Carbon Tetrachloride / Q000494:pharmacology*; D002725:Chloroform / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism; D008715:Methionine / Q000096:biosynthesis*; D009609:Nitrous Oxide / Q000494:pharmacology; D014240:Trichloroethanes / Q000494:pharmacology; D014805:Vitamin B 12 / Q000037:antagonists & inhibitors*
D014240:Trichloroethanes; D002725:Chloroform; D008715:Methionine; D002251:Carbon Tetrachloride; D013766:5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; D001975:Bromotrichloromethane; D009609:Nitrous Oxide; D014805:Vitamin B 12