[Capillary microscopy controlled nail fold biopsy in the diagnosis of collagen disease and vasculitis].
In cases of suspected microangiopathies morphologic abnormal capillaries were identified and marked by nailfold capillary microscopy (NCM). The marked nailfold areas were precisely biopsied and the biopsies were examined by electronic-microscopy and light microscopy (HE and immune-histochemical). Histological findings well correlated with clinical and capillaroscopical findings. It is concluded that NCM-assisted nailfold biopsy helps to achieve histologic proof of microangiopathies and improves diagnostic accuracy in collagen vascular diseases and vasculitides.
von Bierbrauer
A
A
Philipps-Universität Marburg.
Mennel
H D
HD
Leyhe
A
A
von Wichert
P
P
D001706:Biopsy; D002196:Capillaries / Q000473:pathology; D003095:Collagen Diseases / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008853:Microscopy; D008875:Middle Aged; D009131:Muscle, Smooth, Vascular / Q000473:pathology*; D009262:Nails / Q000098:blood supply*; D014657:Vasculitis / Q000175:diagnosis* / Q000473:pathology
Die kapillarmikroskopisch gezielte Nagelfalzbiopsie in der Kollagenose- und Vaskulitis-Diagnostik.