Effect of extra-genital Schistosoma mansoni and Echinostoma caproni infections on serum levels of pregnancy-associated murine protein-1 during murine pregnancy.
Maternal plasma levels of pregnancy-associated murine protein-1 (PAMP-1) were measured by rocket immunoelectrophoresis in BALB/cABom mice experimentally infected with the two intestinal parasites Schistosoma mansoni and Echinostoma caproni. In the first half of pregnancy the PAMP-1 level was significantly lower in the infected females compared with the healthy controls, indicating that PAMP-1 is not essential for implantation and early gestation. In the latter half of pregnancy a rapid increase in the plasma levels of PAMP-1 in the infected females was recorded. This might suggest that pituitary GH secretion is restored in the infected animals during the second half of gestation.
Bindseil
E
E
Department of Pharmacology and Pathobiology, Royal Veterinary and Agricultural University, Copenhagen, Frederiksberg, Denmark.
Andersen
L L
LL
Krog
N L
NL
Hau
J
J
D000818:Animals; D004451:Echinostomiasis / Q000097:blood*; D005260:Female; D051379:Mice; D008807:Mice, Inbred BALB C; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000097:blood*; D011257:Pregnancy Proteins / Q000097:blood*; D012016:Reference Values; D012555:Schistosomiasis mansoni / Q000097:blood*
D011257:Pregnancy Proteins; C033484:pregnancy-associated murine protein 1