title: Effects of maternal sickle cell haemoglobinopathy on pregnancy.
abstract: In order to determine the significant factors which may contribute to complications in pregnant mothers with sickle cell haemoglobinopathy, a study was considered on 100 mothers (35 SS and 65 AS) and the results were compared with 20 control women with normal haemoglobin electrophoretic pattern. The incidence of vaso-occlusive was significant in mothers with sickle cell disease. Furthermore, it was observed that high levels of fetal haemoglobin did not have any beneficial effect in patients with sickle disease during vaso-occlusive episodes.
authors.affiliation: Gynaecology and Obstetric Department, Assiut University, Cairo, Egypt.
authors.forename: M
authors.initials: M
authors.lastname: Salah
authors.forename: M
authors.initials: M
authors.lastname: Massoud
authors.forename: W A
authors.initials: WA
authors.lastname: Saleh
mesh_terms: D000022:Abortion, Spontaneous / Q000453:epidemiology; D000208:Acute Disease; D000755:Anemia, Sickle Cell / Q000097:blood / Q000453:epidemiology* / Q000235:genetics; D003241:Consanguinity; D036861:Delivery, Obstetric / Q000379:methods; D005260:Female; D006769:Hospitals, General; D006801:Humans; D015985:Precipitating Factors; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000097:blood / Q000453:epidemiology*; D011256:Pregnancy Outcome; D012529:Saudi Arabia / Q000453:epidemiology