title: Albumin Paris 2: a new genetic variant distinguished by isoelectric focusing.
abstract: Until recently, the characterization of genetic variants of human serum albumin was performed by electrophoretic typing prior to the determination of their amino acid substitutions. We describe a procedure using isoelectric focusing in the presence of urea for the analysis of the genetic variation of albumin. This procedure allowed a clear distinction of a new variant, previously found to be identical with albumin Sondrio according to its relative electrophoretic mobilities at 3 pHs. This new variant, the third rare albumin allotype identified in the Ile-de-France region, was called albumin Paris 2.
authors.affiliation: Laboratoire d'Immunochimie Analytique, Institut National de Transfusion Sanguine, Paris, France.
authors.forename: D
authors.initials: D
authors.lastname: Rochu
authors.forename: H
authors.initials: H
authors.lastname: Crespeau
authors.forename: J M
authors.initials: JM
authors.lastname: Fine
mesh_terms: D000595:Amino Acid Sequence; D014644:Genetic Variation; D006801:Humans; D007525:Isoelectric Focusing; D012709:Serum Albumin / Q000737:chemistry / Q000235:genetics* / Q000302:isolation & purification
chemical_list: D012709:Serum Albumin