Fluoxetine potentiation by buspirone: three case histories.
The potentiation of fluoxetine by buspirone is described in three cases of treatment-resistant depression. All three patients improved markedly with very few side-effects from the medication. The possibility of synergy between drugs that affect serotonin reuptake inhibition, 5HT1A receptors and 5HT2 receptors is discussed.
Bakish
D
D
University of Ottawa, Ontario.
D000328:Adult; D002065:Buspirone / Q000008:administration & dosage*; D002998:Clonazepam / Q000008:administration & dosage; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005260:Female; D005473:Fluoxetine / Q000008:administration & dosage*; D006801:Humans; D014196:Trazodone / Q000008:administration & dosage; D014364:Tryptophan / Q000008:administration & dosage
D005473:Fluoxetine; D002998:Clonazepam; D014364:Tryptophan; D002065:Buspirone; D014196:Trazodone