[Results of neuroleukemia prevention in children with acute lymphoblastic leukemia].
The follow-up of 318 children with acute lymphoblastic leukemia given program therapy that included different treatments including chemo- and radioprevention of neuroleukemia demonstrated the high efficacy of the measures carried out, which reduced the incidence of neuroleukemia to 5.6%. No gross changes on the part of the neuropsychic status were revealed in the course of the follow-up of children who received the combined prophylaxis of neuroleukemia. The derangement of the CNS was recorded in 17 patients and ran its course in the form of leukemic meningitis and meningoencephalitis.
Maiakova
S A
SA
Moiseenko
E I
EI
Tsygankin
V I
VI
Vil'chevskaia
E V
EV
Bondarenko
L V
LV
Kuznetsova
E I
EI
Zaĭtseva
T I
TI
Meluzova
O M
OM
Lobanov
G V
GV
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001921:Brain / Q000528:radiation effects*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D008577:Meningeal Neoplasms / Q000517:prevention & control*; D008590:Meningoencephalitis / Q000517:prevention & control*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000532:radiotherapy / Q000628:therapy*; D011879:Radiotherapy Dosage
Rezul'taty profilaktiki neĭroleĭkoza u deteĭ s ostrym limfoblastnym leĭkozom.