title: Müllerian tract abnormalities and associated auditory defects.
abstract: Fifteen women with müllerian defects and a control population of 15 with normal müllerian systems underwent dynamic audiometric testing. The rate of auditory defects in women with müllerian abnormalities (33%) was significantly higher (P less than .05) than in the control population (0%). Those patients manifested mild, moderate and severe sensorineural defects in the high-frequency range. The defects were not accounted for by age or occupation and were associated with renal agenesis in 60% of the cases. One patient with normal audiometric testing and a septate uterus had a family history significant for an identical twin sister with unilateral renal agenesis, ipsilateral congenital deafness and an unevaluated müllerian tract. The results of the study suggest that a spectrum of auditory changes may exist in association with müllerian defects, ranging from previously described congenital deafness to more subtle hearing defects not clinically evident.
authors.affiliation: Department of Obstetrics and Gynecology, Tripler Army Medical Center, Honolulu, Hawaii 96859-5000.
authors.forename: G S
authors.initials: GS
authors.lastname: Letterie
authors.forename: N
authors.initials: N
authors.lastname: Vauss
mesh_terms: D000328:Adult; D001299:Audiometry; D001309:Auditory Threshold; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics; D006801:Humans; D009095:Mullerian Ducts / Q000002:abnormalities*