[Ways of increasing the efficacy of antibiotic therapy in young children with severe forms of acute pneumonia].
Examination of 136 children with the severe form of acute pneumonia treated in a resuscitation unit revealed a marked suppression of the immunity and lowered antibiotic sensitivity of the bacterial microflora isolated from the respiratory tracts. The patients were previously treated with antibiotics of 2 to 5 families. Auto-blood irradiated with X-rays without the host was transfused to 72 children (group 1) with immunomodulating purposes. 64 children (group 2) were treated with the same purposes with eleuterococcus, pentoxyl and methyluracil. After transfusion of the auto-blood irradiated with x-rays without the host there was an increase in the antibiotic sensitivity of the bacterial flora along with a marked and rapid improvement of the immunity status. The severe state was alleviated earlier in the patients of group 1. The inflammatory lesions in the lungs of the group 1 patients were arrested sooner and the patients were discharged from the hospital 11 days earlier than the children treated with the routine immunomodulators.
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D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D011014:Pneumonia / Q000188:drug therapy*; D012720:Severity of Illness Index
D000900:Anti-Bacterial Agents
Puti povysheniia éffektivnosti antibiotikoterapii pri tiazhelykh formakh ostroĭ pnevmonii u deteĭ rannego vozrasta.