High-dose carboplatinum and VP-16 in treatment of metastatic adrenal carcinoma.
We describe a case of a patient that presented to our center with Cushing syndrome and was found to have an extensive metastatic adrenal carcinoma. He underwent debulking of the abdominal disease followed by eight courses of VP-16/carboplatinum. The patient had a remarkable response and is currently alive and in complete remission.
Ayass
M
M
Department of Pediatrics, University of Florida College of Medicine, Gainesville.
Gross
S
S
Harper
J
J
D000306:Adrenal Cortex Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D016190:Carboplatin / Q000008:administration & dosage*; D003480:Cushing Syndrome / Q000000981:diagnostic imaging / Q000188:drug therapy; D003937:Diagnosis, Differential; D005047:Etoposide / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D008297:Male; D009362:Neoplasm Metastasis; D011859:Radiography
D005047:Etoposide; D016190:Carboplatin