A new alkaloid antibiotic tetrazomine. Structure determination.
A new alkaloid antibiotic tetrazomine was isolated from the culture broth of Saccharothrix mutabilis subsp. chichijimaensis subsp. nov., and its structure was determined to be I by means of spectroscopic measurements. It has an unusual structure which consists of six rings, including piperidine, piperazine, oxazole, and pyrrolidine rings.
Sato
T
T
Biomedical Research Laboratories I, Yamanouchi Pharmaceutical Co., Ltd., Tokyo, Japan.
Hirayama
F
F
Saito
T
T
Kaniwa
H
H
D000470:Alkaloids / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry*; D010880:Piperidines / Q000737:chemistry
D000470:Alkaloids; D000900:Anti-Bacterial Agents; D010880:Piperidines; C069637:tetrazomine