title: Reproducibility of renal blood flow estimation in the miniature pig using 99Tcm-DTPA: introducing semiautomatic processing.
abstract: This study examines the reproducibility of renal blood flow measurement (RBF) in nine miniature pigs using 99Tcm-DTPA renography, and introduces a new algorithm useful in data processing. Renal blood flow can be estimated using three arterial regions of interest (ROI), the left ventricle (LV), the right lung (RL) and the aorta. Using the LV ROI, left kidney RBF was 9.08 (S.D. 1.69) and right RBF was 10.87 (S.D. 2.26). Reproducibility was assessed by performing renograms on successive days in nine pigs and was found to be best for LV [S.D. of change 0.32 for the left kidney (LK) and 0.74 for the right kidney (RK)] followed by RL (0.77 for LK and 0.75 for RK) and worst for aorta (1.47 for LK and 1.78 for RK).
authors.affiliation: Department of Nuclear Medicine, HSC, London, UK.
authors.forename: J P
authors.initials: JP
authors.lastname: Kelleher
authors.forename: P
authors.initials: P
authors.lastname: Brzeski
authors.forename: P J
authors.initials: PJ
authors.lastname: Anderson
authors.forename: I
authors.initials: I
authors.lastname: Gordon
authors.forename: M E
authors.initials: ME
authors.lastname: Snell
mesh_terms: D000465:Algorithms; D000818:Animals; D011866:Radioisotope Renography / Q000379:methods*; D012079:Renal Circulation / Q000502:physiology*; D015203:Reproducibility of Results; D013552:Swine; D013556:Swine, Miniature; D016284:Technetium Tc 99m Pentetate
chemical_list: D016284:Technetium Tc 99m Pentetate