title: Distinctions in DNA and protein profiles among clinical isolates of Mycoplasma pneumoniae.
abstract: Clinical isolates of Mycoplasma pneumoniae previously shown to exhibit significant sequence divergency in a major 170 kDa adhesin, designated P1, were further characterized using restriction enzyme fingerprinting of genomic DNA and two-dimensional gel electrophoresis of total proteins. Numerous differences in DNA restriction patterns and protein profiles were found, possibly reflecting various degrees of virulence and antigenic potential.
authors.affiliation: Department of Microbiology, University of Texas Health Science Center, San Antonio 78284-7758.
authors.forename: C J
authors.initials: CJ
authors.lastname: Su
authors.forename: S F
authors.initials: SF
authors.lastname: Dallo
authors.forename: H
authors.initials: H
authors.lastname: Alderman
authors.forename: J B
authors.initials: JB
authors.lastname: Baseman
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D016172:DNA Fingerprinting; D004269:DNA, Bacterial / Q000235:genetics*; D015180:Electrophoresis, Gel, Two-Dimensional; D006801:Humans; D009177:Mycoplasma pneumoniae / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial