[Effect of various factors on the distribution of inhaled substances].
Pulmonary radioaerosol distribution at different inhalation regimens was studied in 11 patients with chronic nonspecific pulmonary disease and 28 individuals without respiratory abnormalities by radionuclide assay by employing 99mTc-labelled human albumin. Respiration rate had the most significant action on the penetration of inhaled particles in the preset values. During inhalation, cough was an important determinant of inhaled aerosol distribution. Causes of these influences are considered in the paper.
Kobylianskiĭ
V I
VI
D000280:Administration, Inhalation; D000336:Aerosols; D000418:Albumins / Q000008:administration & dosage / Q000493:pharmacokinetics*; D001991:Bronchitis / Q000503:physiopathology*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000502:physiology* / Q000503:physiopathology; D008954:Models, Biological; D012123:Pulmonary Ventilation / Q000502:physiology*; D011877:Radionuclide Imaging; D013668:Technetium Tc 99m Aggregated Albumin; D014939:Work of Breathing / Q000502:physiology*
D000336:Aerosols; D000418:Albumins; D013668:Technetium Tc 99m Aggregated Albumin
Vliianie razlichnykh foktorov na raspredelenie ingalirovannykh veshchestv.