[The effect of ethanol on increased expression of HLA-A,-B antigens on lymphocytes].
Ethanol in a concentration of 0.001% to 2% increases the expressivity of HLA-A, B antigens on lymphocytes. In 26.13% of the examinations HLA antigens were proved only on lymphocytes processed with ethanol. The expressivity is maximally enhanced already by short-term incubation of lymphocytes with ethanol; if prolonged to 120 mins at 20 degrees C ethanol does not produce an unspecific positivity of results. There is no difference between processing of lymphocytes at 20 degrees C and 37 degrees C. 1% and 2% ethanol facilitates detection of HLA-A, B antigens after addition to serum and lymphocytes in the first stage of the microlymphocytotoxic test.
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Ustav hematologie a krevní transfúze, Praha.
D000431:Ethanol / Q000494:pharmacology*; D015234:HLA-A Antigens / Q000032:analysis*; D015235:HLA-B Antigens / Q000032:analysis*; D006801:Humans; D008214:Lymphocytes / Q000276:immunology*
D015234:HLA-A Antigens; D015235:HLA-B Antigens; D000431:Ethanol
Zvýsení expresivity HLA-A, B antigenů na lymfocytech etanolem.