title: [Nelson's syndrome concomitant with Cushing's syndrome].
abstract: A case is presented of Nelson's Syndrome concomitant with Cushing's Syndrome in a female patient who underwent five years earlier bilateral adrenalectomy due to Cushing's Disease. Together with hyperpigmentation, very elevated ACTH, and intrasellar mass in CT scan, plasma cortisol levels without rythm and not suppressible were observed as well as increased cortisol in urine. The macroadenoma was resected though the sphenoid and later hypophysis radiotherapy was given, with a clinical remission and biochemical improvement of the syndrome. At the present time, slightly elevated ACTH levels persist, with panhypopituitarism and empty sella turcica. The clinical picture is described and a literature search is carried out.
authors.affiliation: Servicio de Endocrinología, Hospital Puerta de Hierro, Madrid.
authors.forename: A
authors.initials: A
authors.lastname: Vicente Delgado
authors.forename: T
authors.initials: T
authors.lastname: Lucas Morante
authors.forename: C
authors.initials: C
authors.lastname: Páramo Fernández
authors.forename: J
authors.initials: J
authors.lastname: Estrada García
authors.forename: M
authors.initials: M
authors.lastname: Marazuela Aspiroz
authors.forename: C
authors.initials: C
authors.lastname: de la Cuerda Compés
mesh_terms: D000328:Adult; D003480:Cushing Syndrome / Q000150:complications* / Q000503:physiopathology / Q000601:surgery; D005260:Female; D006801:Humans; D009347:Nelson Syndrome / Q000150:complications* / Q000503:physiopathology; D010913:Pituitary-Adrenal System
vernacular_title: Síndrome de Nelson concomitante con síndrome de Cushing.