title: [Use of alpha interferon preparations in acute lymphoblastic leukemia in children during remission].
abstract: The Soviet alpha-interferon drugs (human leukocytic interferon, reaferon) were used in the program of the treatment of children with acute lymphoblastic leukemia (during remission). The treatment was found to be more effective with an increase of its duration, relapse-free course of the disease (69.4-82.3%) and survival (70.1-93.1%) of patients with an unfavourable disease prognosis (over 5 years).
authors.forename: I E
authors.initials: IE
authors.lastname: Gavrilova
authors.forename: I P
authors.initials: IP
authors.lastname: Kuznetsov
authors.forename: L A
authors.initials: LA
authors.lastname: Denisov
authors.forename: S A
authors.initials: SA
authors.lastname: Maiakova
authors.forename: T G
authors.initials: TG
authors.lastname: Orlova
authors.forename: Z G
authors.initials: ZG
authors.lastname: Kadagidze
authors.forename: L A
authors.initials: LA
authors.lastname: Makhonova
mesh_terms: D000293:Adolescent; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007370:Interferon Type I / Q000627:therapeutic use*; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000401:mortality / Q000628:therapy*; D011379:Prognosis; D011994:Recombinant Proteins; D012074:Remission Induction
chemical_list: D000970:Antineoplastic Agents; D007370:Interferon Type I; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins
vernacular_title: Primenenie preparatov alfa-interferona pri ostrom limfoblastnom leĭkoze u deteĭ v periode remissii.