[75 years of Cignolin].
Eugen Galewsky (1864-1935), dermatologist in Dresden, introduced 1,8-dihydroxyanthrone (Cignolin, Dithranol) for therapy of psoriasis. He intended to substitute Chrysarobin, a synthetic product, which causes strong discolouring and irritation of skin. In 1916 the firm Farbenfabrik Bayer, Leverkusen, obtained a patent for synthesis of 1.8-dihydroxyanthrone by an inexpensive method. There is a reason to believe that the brother of Eugen Galewsky, the chemist Paul Galewsky, was a co-worker to the Farbenfabrik Bayer and that he recommended his brother Eugen testing Cignolin. Even now Cignolin is still used in the treatment of psoriasis.
Scholz
A
A
Hautabteilung, Medizinischen Akademie Carl Gustav Carus, Dresden.
Kadner
H
H
D000875:Anthralin / Q000266:history*; D005858:Germany; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D011565:Psoriasis / Q000188:drug therapy / Q000266:history
D000875:Anthralin
75 Jahre Cignolin.