Recombinant hirudin: genetic engineering and structure analysis.
Märki
W E
WE
Ciba-Geigy Ltd., Biotechnology Department, Basel, Switzerland.
Grossenbacher
H
H
Grütter
M G
MG
Liersch
M H
MH
Meyhack
B
B
Heim
J
J
D000595:Amino Acid Sequence; D000818:Animals; D001412:Bacillus subtilis / Q000235:genetics; D001665:Binding Sites; D004247:DNA / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics; D006629:Hirudins / Q000031:analogs & derivatives / Q000096:biosynthesis / Q000235:genetics* / Q000378:metabolism; D007865:Leeches / Q000235:genetics; D008969:Molecular Sequence Data; D015394:Molecular Structure; D016297:Mutagenesis, Site-Directed; D011485:Protein Binding; D011487:Protein Conformation; D011993:Recombinant Fusion Proteins / Q000235:genetics* / Q000378:metabolism; D011994:Recombinant Proteins; D012441:Saccharomyces cerevisiae / Q000235:genetics; D013329:Structure-Activity Relationship; D013917:Thrombin / Q000037:antagonists & inhibitors / Q000378:metabolism
D006629:Hirudins; D011993:Recombinant Fusion Proteins; D011994:Recombinant Proteins; C072298:hirudin HV1; C072299:hirudin HV2; C072300:hirudin HV3; D004247:DNA; D013917:Thrombin; C060225:desirudin