title: [Determination of chlorphenamine and propantheline bromide in pukeling tablets by differential--linear combination derivative spectrophotometry].
abstract: This paper provides the basic principle and experimental technique of differential--linear combination equal value derivative spectrophotometry. Quantitative analysis of three or four component--mixture can be done without separation. This method was investigated to assay the contents of chlorphenamine and propantheline bromide in Pukeling tablets by using UV-210A spectrophotometer. The average recoveries of chlorphenamine and propantheline bromide were 100.2 +/- 1.49% (CV) and 99.89 +/- 1.03% (CV) respectively. The results showed that it not only can effectively remove disturbances from each other, but also give higher sensitivity and accuracy.
authors.affiliation: Weifang Institute for Drug Control.
authors.forename: L M
authors.initials: LM
authors.lastname: Lin
authors.forename: N J
authors.initials: NJ
authors.lastname: Zhang
authors.forename: H Y
authors.initials: HY
authors.lastname: Wang
mesh_terms: D002744:Chlorpheniramine / Q000032:analysis*; D004338:Drug Combinations; D011413:Propantheline / Q000032:analysis*; D013056:Spectrophotometry, Ultraviolet / Q000379:methods; D013607:Tablets / Q000032:analysis
chemical_list: D004338:Drug Combinations; D013607:Tablets; D011413:Propantheline; D002744:Chlorpheniramine