title: Anticoccidial efficacy of diclazuril against recent field isolates of Eimeria from turkey farms in the United States.
abstract: In a series of laboratory tests, diclazuril was evaluated for efficacy against Eimeria adenoeides, E. meleagrimitis, E. gallopavonis, and a mixture of the three species. Four isolates of each of the species were tested. When given at 0.5, 1.0, and 1.5 ppm in the feed, diclazuril was highly efficacious against all three species and against mixtures of the three, as judged by protection against mortality from coccidiosis, reduction in droppings scores, and improvement of weight gains compared with unmedicated controls. When diclazuril was given at 1.0 ppm, the improvement in droppings scores and weight gains was better than when 0.5 ppm of diclazuril was given. Increasing the dosage to 1.5 ppm did not appear to offer any consistent or significant improvement over 1.0 ppm.
authors.affiliation: Department of Poultry Science, University of Georgia, Athens 30602.
authors.forename: L R
authors.initials: LR
authors.lastname: McDougald
authors.forename: G F
authors.initials: GF
authors.lastname: Mathis
authors.forename: B P
authors.initials: BP
authors.lastname: Seibert
mesh_terms: D000818:Animals; D003048:Coccidiosis / Q000188:drug therapy / Q000662:veterinary*; D003049:Coccidiostats / Q000494:pharmacology / Q000627:therapeutic use; D004539:Eimeria / Q000187:drug effects*; D005260:Female; D008297:Male; D009570:Nitriles / Q000494:pharmacology / Q000627:therapeutic use*; D011201:Poultry Diseases / Q000188:drug therapy*; D011897:Random Allocation; D014227:Triazines / Q000494:pharmacology / Q000627:therapeutic use*; D014422:Turkeys; D014481:United States; D015430:Weight Gain
chemical_list: D003049:Coccidiostats; D009570:Nitriles; D014227:Triazines; C057884:diclazuril