title: Antimicrobial N-methylpyridinium salts related to the xestamines from the Caribbean sponge Calyx podatypa.
abstract: Two antimicrobial fractions were obtained from the sponge Calyx podatypa from the Bahamas. The less polar fraction contained the known compounds xestamines A [1] and B [2] and three new metabolites called xestamines D [3], E [4], and F [5]. The more polar fraction consisted of a mixture of xestamines G [6] and H [7].
authors.affiliation: Scripps Institution of Oceanography, University of California at San Diego, La Jolla 92093-0212.
authors.forename: D B
authors.initials: DB
authors.lastname: Stierle
authors.forename: D J
authors.initials: DJ
authors.lastname: Faulkner
mesh_terms: D000470:Alkaloids / Q000302:isolation & purification / Q000494:pharmacology*; D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification; D001156:Artemia / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D011161:Porifera / Q000302:isolation & purification*; D011725:Pyridines / Q000302:isolation & purification / Q000494:pharmacology*; D011726:Pyridinium Compounds / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000470:Alkaloids; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D011725:Pyridines; D011726:Pyridinium Compounds