[The interrelation between the formation of oleandomycin and the resistance to it in different strains of Streptomyces antibioticus].
Strains, producers of oleandomycin, with different level of antibiotic-formation have been studied for their resistance to their own antibiotic. The obtained highly active strain possesses double resistance to oleandomycin and 50% higher activity. Identity of oleandomycin phosphate substances synthesized by initial and produced highly active strains is shown by the HELC method.
Shevchenko
A A
AA
Tyshchenko
A F
AF
Ryzhakova
L B
LB
Matseliukh
B P
BP
D002851:Chromatography, High Pressure Liquid; D004305:Dose-Response Relationship, Drug; D004352:Drug Resistance, Microbial; D009827:Oleandomycin / Q000032:analysis / Q000037:antagonists & inhibitors* / Q000096:biosynthesis*; D013303:Streptomyces antibioticus / Q000187:drug effects* / Q000378:metabolism*; D013997:Time Factors
D009827:Oleandomycin
Vzaimosviaz' mezhdu obrazovaniem oleandomitsina i ustoĭchivost'iu k nemu u razlichnykh shtammov Streptomyes antibioticus.