[Peptidergic modulation of the vagal effect on heart rhythm].
In 20 experiments on anesthetised cats burst stimulation of peripheral cut end of right vagus nerve leads to synchronisation of cardiac and vagus rhythms. Inhibitory effect of dalargin was caused by a decrease of tonic component while secretin would selectively inhibit synchronizing component. The observed results testify to existence of selective peptidergic modulation of vagus influence on the cardiac rhythm.
Pokrovskiĭ
V M
VM
Osadchiĭ
O E
OE
Kurzanov
A N
AN
D000818:Animals; D002415:Cats; D004558:Electric Stimulation; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives / Q000494:pharmacology; D005260:Female; D006339:Heart Rate / Q000187:drug effects / Q000502:physiology; D008297:Male; D012633:Secretin / Q000494:pharmacology; D013565:Sympatholytics / Q000494:pharmacology; D014630:Vagus Nerve / Q000187:drug effects / Q000502:physiology*
D013565:Sympatholytics; D012633:Secretin; D016308:Enkephalin, Leucine-2-Alanine; C040996:enkephalin-Leu, Ala(2)-Arg(6)-
Peptidergicheskaia moduliatsiia vagusnogo vliianiia na serdechnyĭ ritm.