title: [A comparative study of the efficacy of josamycin versus oral penicillin in the treatment of acute tonsillitis].
abstract: We have compared the efficacy josamycin (750 mg/12 h/orally) versus penicillin V (500 mg/8 h) for the treatment of acute tonsillitis in a prospective randomized study. Of the 82 eligible patients, 18 were diagnosed of infectious mononucleosis and excluded and the remaining 64 could be evaluated. The duration of the fever and the clinical evolution was similar away the 31 randomized to receive josamycin and the 27 treated with penicillin. In conclusion, josamycin seems to be a useful alternative to penicillin for the treatment of acute tonsillitis.
authors.affiliation: Servicio de Enfermedades Infecciosas, Hospital Clínic i Provincial, Barcelona.
authors.forename: E
authors.initials: E
authors.lastname: Aznar
authors.forename: F
authors.initials: F
authors.lastname: Sabater
authors.forename: J
authors.initials: J
authors.lastname: Cobarro
authors.forename: J
authors.initials: J
authors.lastname: Puig
authors.forename: J
authors.initials: J
authors.lastname: Mensa
mesh_terms: D000208:Acute Disease; D000284:Administration, Oral; D000328:Adult; D001419:Bacteria / Q000302:isolation & purification; D005260:Female; D006801:Humans; D015570:Josamycin / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D010404:Penicillin V / Q000008:administration & dosage / Q000627:therapeutic use*; D011446:Prospective Studies; D014069:Tonsillitis / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D015570:Josamycin; D010404:Penicillin V
vernacular_title: Estudio comparativo de la eficacia de josamicina frente a penicilina oral en el tratamiento de la amigdalitis aguda.