[Life expectancy after a first attack of sustained monomorphic ventricular tachycardia. Apropos of 295 patients with a follow-up of more than 5 years].
Analysis of actuarial cardiac mortality of 295 patients after a first attack of sustained monomorphic ventricular tachycardia followed up for an average of 5.1 years showed that: the aetiology was the main prognostic factor. Patients with a normal left ventricle had a zero 5 year mortality rate (normal heart) or 3% (arrhythmogenic right ventricular dysplasia) compared with 24% in patients with cardiomyopathy and 40% with myocardial infarction: p less than 0.01. Similar results were obtained if sudden death was considered; in patients with left-ventricular disease, the role of pump function assessed by the ejection fraction was essential: the 5 year mortality was 14.5% (cardiomyopathy) and 30% (myocardial infarction) if this was greater than 0.3 compared to 43% and 51% respectively when less than 0.3 (p less than 0.01); the heart rate of spontaneous ventricular tachycardia and that of tachycardia induced during endocavitary investigation had no influence on the mortality. However, the mortality following a first tachycardia with syncope was higher than that following a well tolerated tachycardia (p less than 0.5 if the ejection fraction less than or equal to 0.3 and p less than 0.001 if greater than 0.3).(ABSTRACT TRUNCATED AT 250 WORDS)
Leclercq
J F
JF
Clinique cardiologique, hôpital Lariboisière, Paris.
Leenhardt
A
A
Ruta
I
I
Cauchemez
B
B
Chouty
F
F
Denjoy
I
I
Maison-Blanche
P
P
Coumel
P
P
Slama
R
R
D000206:Actuarial Analysis; D000328:Adult; D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D005500:Follow-Up Studies; D006352:Heart Ventricles; D006801:Humans; D008017:Life Expectancy; D008875:Middle Aged; D011379:Prognosis; D012008:Recurrence; D012189:Retrospective Studies; D015996:Survival Rate; D013610:Tachycardia / Q000188:drug therapy / Q000401:mortality* / Q000503:physiopathology; D016277:Ventricular Function, Left
D000889:Anti-Arrhythmia Agents
Espérance de vie après une première crise de tachycardie ventriculaire monomorphe soutenue. A propos de 295 patients suivis plus de 5 ans.