title: Characteristics of extracellular protein production by a plasmidless derivative of Staphylococcus simulans biovar staphylolyticus.
abstract: A derivative of Staphylococcus simulans biovar staphylolyticus cured of all five plasmids present in the wild-type organism was developed, and the characteristics of extracellular protein production by this plasmidless strain were compared to those of the wild type. Although staphylolytic endopeptidase (lysostaphin) and beta-lactamase are known to be plasmid encoded, analysis of this cured strain revealed that most other extracellular proteins are chromosomally encoded.
authors.affiliation: Department of Microbiology, University of Alabama, Tuscaloosa 35487.
authors.forename: J D
authors.initials: JD
authors.lastname: Nitterauer
authors.forename: H E
authors.initials: HE
authors.lastname: Heath
authors.forename: L S
authors.initials: LS
authors.lastname: Heath
authors.forename: P A
authors.initials: PA
authors.lastname: LeBlanc
authors.forename: G L
authors.initials: GL
authors.lastname: Sloan
mesh_terms: D001426:Bacterial Proteins / Q000096:biosynthesis* / Q000235:genetics; D004587:Electrophoresis, Agar Gel; D004591:Electrophoresis, Polyacrylamide Gel; D010957:Plasmids; D013210:Staphylococcus / Q000235:genetics / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins