title: Diversity and specificity in transcriptional regulation: the benefits of heterotypic dimerization.
abstract: Many eukaryotic transcription factors contain domains that mediate the formation of homo- and heterodimers. The widespread occurrence of such domains suggests that they are important to the genetic regulatory apparatus. In this review we explore the contributions that heterotypic dimerization may make to the generation of regulatory diversity.
authors.affiliation: Howard Hughes Research Laboratory, Carnegie Institution of Washington, Baltimore, MD 21210.
authors.forename: P
authors.initials: P
authors.lastname: Lamb
authors.forename: S L
authors.initials: SL
authors.lastname: McKnight
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004268:DNA-Binding Proteins / Q000235:genetics; D005786:Gene Expression Regulation; D008969:Molecular Sequence Data; D014158:Transcription, Genetic
chemical_list: D004268:DNA-Binding Proteins