title: [Treatment of dry eye syndrome with lacrimal gel: a randomized multicenter study].
abstract: The appearance on the French market of a carbomer tear substitute, Gel-Larmes, an original galenic form, constitutes a real therapeutic progress in the treatment of dry eye syndrome. An open randomized multicentric trial was conducted comparing the tolerance and efficacy of Gel-Larmes with those of eye drops containing chondroitin sulphate. The statistical analysis evidences an inferior average number of daily instillations for Gel-Larmes, its better efficacy on the symptoms as well as on the objective criteria: biomicroscopic examination, break-up time, rose Bengal test. The tolerance of the product is excellent and 81% of the patients express their wish to pursue Gel-Larmes versus 54% for the reference product.
authors.affiliation: Hôpital St-Antoine, Paris.
authors.forename: L
authors.initials: L
authors.lastname: Laroche
authors.forename: M
authors.initials: M
authors.lastname: Arrata
authors.forename: G
authors.initials: G
authors.lastname: Brasseur
authors.forename: F
authors.initials: F
authors.lastname: Lagoutte
authors.forename: Y
authors.initials: Y
authors.lastname: Le Mer
authors.forename: P
authors.initials: P
authors.lastname: Lumbroso
authors.forename: M
authors.initials: M
authors.lastname: Mercante
authors.forename: F
authors.initials: F
authors.lastname: Normand
authors.forename: D
authors.initials: D
authors.lastname: Rigal
authors.forename: S
authors.initials: S
authors.lastname: Roncin
mesh_terms: D000180:Acrylic Resins / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000998:Antiviral Agents / Q000627:therapeutic use*; D015352:Dry Eye Syndromes / Q000188:drug therapy*; D005260:Female; D005782:Gels; D006801:Humans; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions; D013997:Time Factors
chemical_list: D000180:Acrylic Resins; D000998:Antiviral Agents; D005782:Gels; D009883:Ophthalmic Solutions; C006903:carbopol 940
vernacular_title: Traitement de la sécheresse oculaire par gel lacrymal: étude multicentrique randomisée.