Two cases of gastric antral vascular ectasia--response to medical treatment.
Two patients with severe iron deficiency anemia and gastric antral vascular ectasia (GAVE) are reported. The anemia caused by the chronic blood loss from the abnormally dilated mucosal and submucosal capillary veins in the gastric antrum was unresponsive to oral iron supplementation. However, one of the patients was successfully treated with intramuscular injection of (Asu1,7) eel calcitonin. The other one was treated by oral prednisolone with resulting improvement iron deficiency anemia. The possible mechanisms of successful calcitonin and prednisolone treatments on chronic blood loss from GAVE is discussed.
Kishi
K
K
Department of Internal Medicine, Miki City Hospital, Japan.
Kinoshita
Y
Y
Kitajima
N
N
Itoh
T
T
Watanabe
M
M
Kawanami
C
C
Inadome
T
T
Inoh
T
T
Fukuzaki
H
H
Fukase
M
M
D000368:Aged; D000369:Aged, 80 and over; D000747:Anemia, Hypochromic / Q000188:drug therapy / Q000209:etiology*; D002116:Calcitonin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004108:Dilatation, Pathologic / Q000150:complications / Q000188:drug therapy; D005260:Female; D005352:Fibromuscular Dysplasia / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use*; D011706:Pyloric Antrum / Q000098:blood supply*
D002116:Calcitonin; D011239:Prednisolone; C012755:elcatonin