title: Development of resistance in laboratory animals to adults of the tick Rhipicephalus evertsi evertsi.
abstract: Acquired resistance to adults of the two-host tick Rhipicephalus evertsi evertsi Neumann has been demonstrated in guinea-pigs and rabbits. Four infestations of both hosts with R.e.evertsi adults resulted in a significant reduction in the mean weight of the engorged females. A decline in the mean weight of the female ticks was also observed in ticks which fed on a rabbit previously injected with serum taken from a rabbit resistant to R.e.evertsi. This suggests that humoral immunity may have an important role in the acquired resistance to ticks. In both hosts an increase in the level of serum globulins was recorded. In rabbits the level of gamma globulin was affected, while in guinea-pigs an increase was observed in the concentration of alpha 1 and beta globulins. The differences in host responses to the R.e.evertsi adults are discussed.
authors.affiliation: Department of Biology, Medical University, Medunsa, South Africa.
authors.forename: Y
authors.initials: Y
authors.lastname: Rechav
authors.forename: F C
authors.initials: FC
authors.lastname: Clarke
authors.forename: D A
authors.initials: DA
authors.lastname: Els
authors.forename: J
authors.initials: J
authors.lastname: Dauth
mesh_terms: D000818:Animals; D000830:Animals, Laboratory; D005260:Female; D006168:Guinea Pigs / Q000469:parasitology*; D008297:Male; D011817:Rabbits / Q000469:parasitology*; D012376:Rodent Diseases / Q000276:immunology*; D013984:Tick Infestations / Q000276:immunology / Q000662:veterinary*; D013987:Ticks / Q000276:immunology*