title: Pressure support ventilation using a new tracheal gas injection tube.
abstract: In order to explore new types of jet ventilation, we tested a tracheal gas injection tube (TGIT) which included six thin capillaries and provided high pressure injection. The driving pressure was chosen to yield a plateau of inspiratory tracheal pressure of 10 cm H2O. An original controller was built to monitor spirometry and trigger injection in order to deliver both pressure controlled ventilation (PCVTGIT) and a new mode of inspiratory pressure support jet ventilation (IPSTGIT). The PVCTGIT mode maintained the same end-tidal carbon dioxide concentration as conventional ventilation with the same tidal and minute ventilation. We studied 10 patients after abdominal surgery. During spontaneous breathing, the patients were allowed to breathe through the tube, successively with and without IPSTGIT. IPSTGIT, compared with spontaneous breathing increased minute ventilation (from 5.7 (SD 1.6) to 7.1 (1.7) litre min-1) (P less than 0.001). It reduced the total work of breathing (from 0.625 (0.223) to 0.263 (0.151) J litre-1, respectively) (P less than 0.01) and the occlusion pressure (from 2.62 (1.28) to 1.36 (0.74) cm H2O, respectively) (P less than 0.01). It is concluded that this TGIT used with a specific system for sensing and triggering ventilation allows inspiratory pressure support during low frequency jet ventilation.
authors.affiliation: Unité INSERM U296, Hôpital Henri Mondor, Créteil, France.
authors.forename: L
authors.initials: L
authors.lastname: Beydon
authors.forename: D
authors.initials: D
authors.lastname: Isabey
authors.forename: G
authors.initials: G
authors.lastname: Boussignac
authors.forename: F
authors.initials: F
authors.lastname: Bonnet
authors.forename: P
authors.initials: P
authors.lastname: Duvaldestin
authors.forename: A
authors.initials: A
authors.lastname: Harf
mesh_terms: D005260:Female; D006611:High-Frequency Jet Ventilation / Q000295:instrumentation*; D006801:Humans; D007442:Intubation, Intratracheal / Q000295:instrumentation*; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D012119:Respiration / Q000502:physiology; D015656:Respiratory Mechanics / Q000502:physiology; D014939:Work of Breathing / Q000502:physiology