title: Altered permeability of iris vessels following posterior chamber lens implantation: an electron microscopic study.
abstract: Altered permeability of the iris vessels of monkey eyes following extra-capsular cataract extraction and posterior chamber intraocular lens implantation was studied by transmission electron microscopy using horseradish peroxidase (HRP) as a tracer. In control animals, HRP-reaction products were confined to the vascular lumens and to a small number of vesicles on the luminal side of the endothelial cells. In experimental animals, however, the interendothelial junctions of the iris vessels were filled with HRP-reaction products, and the endothelial cells of the iris vessels contained a large number of HRP-labeled plasmalemmal vesicles that opened into the basal lamina. HRP-reaction products were also found in the surrounding iris stroma of these experimental animals.
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ishibashi
authors.forename: S
authors.initials: S
authors.lastname: Sugai
authors.forename: T
authors.initials: T
authors.lastname: Kubota
authors.forename: Y
authors.initials: Y
authors.lastname: Ohnishi
authors.forename: H
authors.initials: H
authors.lastname: Inomata
mesh_terms: D000818:Animals; D001082:Aqueous Humor / Q000378:metabolism; D002199:Capillary Permeability; D002387:Cataract Extraction; D004727:Endothelium / Q000648:ultrastructure; D006735:Horseradish Peroxidase / Q000493:pharmacokinetics; D007365:Intercellular Junctions / Q000648:ultrastructure; D007498:Iris / Q000098:blood supply* / Q000648:ultrastructure; D007910:Lenses, Intraocular; D008251:Macaca
chemical_list: D006735:Horseradish Peroxidase