title: An immunohistochemical study of the collagens of rabbit synovial interstitium.
abstract: The interstitial pathway from joint cavity to synovial transport vessels contains a complex extracellular matrix. Rabbit knee synovial intima contains 3 fibrous elements--banded collagen fibrils, microfibrils and broad banded aggregates. The distribution of 4 types of collagen in rabbit knee synovium was investigated immunohistochemically. Types I and III collagens are both present, although the binding of anti-type I antibody was weak. Type V collagen, which forms thin fibrils, or is copolymerized with type I collagen, and type VI collagen, which forms broad banded aggregates and microfibrils, are widely distributed throughout the intimal and subintimal matrices.
authors.affiliation: Department of Anatomy, St. George's Hospital Medical School, London, UK.
authors.forename: D E
authors.initials: DE
authors.lastname: Ashhurst
authors.forename: Y S
authors.initials: YS
authors.lastname: Bland
authors.forename: J R
authors.initials: JR
authors.lastname: Levick
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal; D003094:Collagen / Q000378:metabolism*; D007150:Immunohistochemistry; D011817:Rabbits; D013583:Synovial Membrane / Q000166:cytology / Q000378:metabolism*
chemical_list: D000911:Antibodies, Monoclonal; D003094:Collagen