title: [An analysis of the possible mechanism of the ulcerostatic action of 1-ethoxysilatrane].
abstract: Stimulating effect of 1-ethoxysilatrane on healing processes of experimental stomach ulcers was studied in rats. 1-ethoxysilatrane inhibited lipid peroxidation in blood and stomach wall tissues, interacted with artificial membranes, and affected the rate of mitochondrial respiration in liver. A hypothesis is put forward on the membranotropic effect of 1-ethoxysilatrane which underlies its ulcerostatic effect.
authors.forename: M M
authors.initials: MM
authors.lastname: Rasulov
authors.forename: I G
authors.initials: IG
authors.lastname: Kuznetsov
authors.forename: L K
authors.initials: LK
authors.lastname: Bartkova
authors.forename: S K
authors.initials: SK
authors.lastname: Suslova
authors.forename: A A
authors.initials: AA
authors.lastname: Belousov
authors.forename: M G
authors.initials: MG
authors.lastname: Voronkov
mesh_terms: D000085:Acetates; D000818:Animals; D000897:Anti-Ulcer Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001643:Bridged Bicyclo Compounds / Q000494:pharmacology / Q000627:therapeutic use*; D019086:Bridged Bicyclo Compounds, Heterocyclic; D004353:Drug Evaluation, Preclinical; D008051:Lipid Bilayers; D015227:Lipid Peroxidation / Q000187:drug effects; D008563:Membrane Lipids; D008564:Membrane Potentials / Q000187:drug effects; D017646:Organosilicon Compounds; D051381:Rats; D012825:Silicon / Q000494:pharmacology / Q000627:therapeutic use*; D013276:Stomach Ulcer / Q000139:chemically induced / Q000188:drug therapy / Q000378:metabolism; D013997:Time Factors; D014945:Wound Healing / Q000187:drug effects
chemical_list: D000085:Acetates; D000897:Anti-Ulcer Agents; D001643:Bridged Bicyclo Compounds; D019086:Bridged Bicyclo Compounds, Heterocyclic; D008051:Lipid Bilayers; D008563:Membrane Lipids; D017646:Organosilicon Compounds; C042292:1-ethoxysilatrane; D012825:Silicon
vernacular_title: Analiz vozmozhnogo mekhanizma ul'tserostaticheskogo deĭstviia 1-étoksisilatrana.