title: Diagnostic potential of IgA coated Candida cells in mucous membrane candidiasis.
abstract: The significance of in vivo IgA coated yeast cells for the diagnosis of candidiasis of the oral and vaginal mucosal membranes was evaluated by direct immunofluorescence in 70 patients with or without clinical symptoms, shown to be positive for yeast growth in the cultural test. Most of the patients with clinically suspected candidiasis of the mucosal membranes gave positive results by serologic assays in contrast to the majority of symptomless patients. The diagnostic approach proved to be essentially consistent with the clinical signs, persistence of infection, response to antifungal therapy and quantitative cultural data.
authors.affiliation: Istituto di Microbiologia, Università degli Studi di Parma, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Polonelli
authors.forename: S
authors.initials: S
authors.lastname: Conti
authors.forename: M G
authors.initials: MG
authors.lastname: Menozzi
authors.forename: M
authors.initials: M
authors.lastname: Gerloni
authors.forename: R
authors.initials: R
authors.lastname: Elosegui
authors.forename: M
authors.initials: M
authors.lastname: Fernandez
authors.forename: M
authors.initials: M
authors.lastname: Alvarez
authors.forename: J
authors.initials: J
authors.lastname: Ponton
mesh_terms: D002175:Candida / Q000276:immunology / Q000302:isolation & purification*; D002180:Candidiasis, Oral / Q000175:diagnosis*; D002181:Candidiasis, Vulvovaginal / Q000175:diagnosis*; D005260:Female; D016650:Fluorescein-5-isothiocyanate; D005455:Fluorescent Antibody Technique; D006801:Humans; D007070:Immunoglobulin A; D011237:Predictive Value of Tests
chemical_list: D007070:Immunoglobulin A; D016650:Fluorescein-5-isothiocyanate