Leukocyte lipid profile in chronic alcoholics.
Polymorphonuclear leukocytic (PNML) lipid content was studied in chronic alcoholic and normal control subjects. Chronic alcoholic subjects showed abnormal liver function and abnormal serum lipid profile. PMNL obtained from chronic alcoholic subjects exhibited decreased free cholesterol and phospholipid contents, with a significant increase in cholesterol to phospholipid ratio. Although, there was no change in the free fatty acids, the levels of triglycerides were significantly elevated.
Chari
S N
SN
Department of Biochemistry, Indira Gandhi Medical College, Nagpur.
Muddeshwar
M G
MG
D000328:Adult; D000410:Alanine Transaminase / Q000378:metabolism; D000437:Alcoholism / Q000097:blood* / Q000201:enzymology / Q000503:physiopathology; D000469:Alkaline Phosphatase / Q000378:metabolism; D001219:Aspartate Aminotransferases / Q000378:metabolism; D006801:Humans; D008055:Lipids / Q000097:blood*; D008099:Liver / Q000201:enzymology / Q000502:physiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000737:chemistry*
D008055:Lipids; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase