Endometrial carcinoma in tamoxifen-treated breast cancer patients.
Tamoxifen is an important agent for the treatment of breast cancer. Occasionally the drug, which is an antiestrogen, has agonistic estrogenic activity. The authors describe three new cases of endometrial carcinoma developing in breast cancer patients taking tamoxifen and stress the necessity of carefully monitoring the uterine cavity under tamoxifen treatment.
Spinelli
G
G
Department of Obstetrics and Gynecology, City Hospital, Prato, Italy.
Bardazzi
N
N
Citernesi
A
A
Fontanarosa
M
M
Curiel
P
P
D001943:Breast Neoplasms / Q000188:drug therapy*; D016889:Endometrial Neoplasms / Q000139:chemically induced*; D004967:Estrogens; D005260:Female; D006801:Humans; D008875:Middle Aged; D009376:Neoplasms, Hormone-Dependent / Q000139:chemically induced* / Q000188:drug therapy; D013629:Tamoxifen / Q000009:adverse effects* / Q000627:therapeutic use
D004967:Estrogens; D013629:Tamoxifen