title: Detection of complications after liver transplantation by technetium-99m mebrofenin hepatobiliary scintigraphy.
abstract: Fifty-five hepatobiliary scintigraphic studies using 99mTc-Mebrofenin were performed in 52 orthotopic liver transplant patients to evaluate suspected biliary complications, namely biliary extravasation and extrahepatic obstruction. Final diagnosis was made by analysis of the clinical course and other procedures. Three out of three studies of biliary leak and four out of five studies of biliary obstruction were detected. There were no false positives in either complication. The sensitivity, specificity and accuracy were 100, 100, 100% for ectravasation and 80, 100, 98% for obstruction, respectively. Hepatobiliary scintigraphy appears to be an accurate means of detecting biliary leak and obstruction associated with the transplanted liver.
authors.affiliation: Department of Radiology, University of Pittsburgh School of Medicine, PA 15213.
authors.forename: T
authors.initials: T
authors.lastname: Mochizuki
authors.forename: W N
authors.initials: WN
authors.lastname: Tauxe
authors.forename: J
authors.initials: J
authors.lastname: Dobkin
authors.forename: A N
authors.initials: AN
authors.lastname: Shah
authors.forename: R
authors.initials: R
authors.lastname: Shanker
authors.forename: S
authors.initials: S
authors.lastname: Todo
authors.forename: T E
authors.initials: TE
authors.lastname: Starzl
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000814:Aniline Compounds; D001660:Biliary Tract Diseases / Q000000981:diagnostic imaging*; D002648:Child; D005260:Female; D005998:Glycine; D006801:Humans; D007098:Imino Acids; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011183:Postoperative Complications / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging
chemical_list: D000814:Aniline Compounds; D007098:Imino Acids; D015609:Organotechnetium Compounds; C034837:technetium Tc 99m mebrofenin; D005998:Glycine