title: [Vitamin D and calcium metabolism in relation to different levels of vitamins B6 and D].
abstract: The influence of vitamin B6 deficiency on some vitamin D-dependent processes was studied in animals. The following parameters changing in relation to the level of vitamin D providing were investigated: activity of alkaline phosphatase in the serum and small intestine mucosa, the levels of Ca, P and parathormone, concentration of vitamin D metabolites and enzyme activity; and only 25-hydroxyvitamin D (25-OVD) concentration in the blood serum, under conditions of combined vitamin B6 and D deficiency was significantly lower as compared to cases with vitamin D deficiency alone. In the presence of vitamin B6 deficiency recovery of 25-OVD level in the blood serum, after vitamin D administration to the animals, had a tendency to delay as compared to that in the animals provided with vitamin B6. Vitamin B6 deficiency produced similar effect on 25-OVD 1-hydroxylase activity. The data obtained have evidenced a possibility of vitamin B6 influence on vitamin D metabolism.
authors.forename: O A
authors.initials: OA
authors.lastname: Klimova
authors.forename: A A
authors.initials: AA
authors.lastname: Sokol'nikov
authors.forename: V M
authors.initials: VM
authors.lastname: Kodentsova
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Glinka
authors.forename: Iu P
authors.initials: IuP
authors.lastname: Arkhapchev
authors.forename: I N
authors.initials: IN
authors.lastname: Sergeev
mesh_terms: D000469:Alkaline Phosphatase / Q000378:metabolism; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D006887:Hydroxycholecalciferols / Q000378:metabolism; D008297:Male; D010281:Parathyroid Hormone / Q000378:metabolism; D010758:Phosphorus / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D026681:Vitamin B 6 Deficiency / Q000378:metabolism*; D014808:Vitamin D Deficiency / Q000378:metabolism*
chemical_list: D006887:Hydroxycholecalciferols; D010281:Parathyroid Hormone; D010758:Phosphorus; D000469:Alkaline Phosphatase; D002118:Calcium
vernacular_title: Obmen vitamina D i kal'tsiia pri razlichnoĭ obespechennosti vitamina B6 i D.