title: Correlation between Korotkoff's sounds and ultrasonics of the brachial artery in healthy and normotensive subjects.
abstract: The clinical measurement of blood pressure is generally obtained by auscultation for Korotkoff's sounds over the brachial artery using a sphygmomanometer and cuff. Real-time two dimensional ultrasound and Doppler techniques were used to study the brachial artery movements and blood flow patterns during these pressure measurements. Simultaneous recordings of Korotkoff's sounds were obtained. A strong correlation in time was demonstrated between Korotkoff's five phases, brachial artery wall movements and specific blood flow patterns. The evidence largely supports what to date has been speculation as to the origin of Korotkoff's sounds in that Korotkoff's phases 1 and 3 appear to be produced by vigorous arterial wall motion and phase 5 by cessation of this movement. Phase 2 is produced by blood flow disturbance. Furthermore, the lack of correlation between phase 4 and any specific vascular event may go some way to explaining why in clinical practice phase 5 readings are now preferred for diastolic pressure.
authors.affiliation: Institute of Nephrology, Cardiff Royal Infirmary, UK.
authors.forename: D A
authors.initials: DA
authors.lastname: Sykes
authors.forename: K
authors.initials: K
authors.lastname: McCarty
authors.forename: E
authors.initials: E
authors.lastname: Mulkerrin
authors.forename: D J
authors.initials: DJ
authors.lastname: Fisher
authors.forename: J P
authors.initials: JP
authors.lastname: Woodcock
mesh_terms: D000328:Adult; D001314:Auscultation / Q000379:methods; D001916:Brachial Artery / Q000000981:diagnostic imaging / Q000502:physiology*; D006801:Humans; D009131:Muscle, Smooth, Vascular / Q000000981:diagnostic imaging / Q000502:physiology; D012016:Reference Values; D012039:Regional Blood Flow; D014463:Ultrasonography