Effect of methanol extract from Monadenium Lugardiae on contractile activity of guinea-pig ileum.
A methanol extract from Monadenium Lugardiae was tested for contractile activity on the guinea-pig ileum using the transmural stimulation method. Results obtained showed that the extract exhibited notable activity on the guinea-pig ileum contraction. Higher concentrations, however, showed inhibitory effect on the guinea-pig ileum contraction as well as its response to transmural stimulation.
Gundidza
M
M
Department of Pharmacy, Faculty of Medicine, University of Zimbabwe, Mount Pleasant, Harare.
D000818:Animals; D004353:Drug Evaluation, Preclinical; D005769:Gastrointestinal Motility / Q000187:drug effects*; D006168:Guinea Pigs; D007082:Ileum / Q000187:drug effects*; D016488:Medicine, African Traditional; D000432:Methanol / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology*; D015030:Zimbabwe
D010936:Plant Extracts; D000432:Methanol