title: Increment of brain temporal perfusion during auditory stimulation. Preliminary study with technetium-99m HMPAO SPET.
abstract: A study on the dynamic exploration of the auditory pathway is presented, in which technetium-99m hexamethylpropylene amine oxime single-photon emission computed tomography (SPET) was used in volunteers with normal hearing. Changes in 99mTc-HMPAO distribution were calculated using a region of interest/whole-brain count ratio. The results showed a temporal perfusion increment of 17% (right) and 19% (left) during tonal supraliminar stimulation, which was significantly different from the control ROI. Sensitivity tests for the method were requested before any clinical application.
authors.affiliation: Department of Oto-Rhino-Laringology, Centre Hospitalo-universitaire de Tours, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Le Scao
authors.forename: J L
authors.initials: JL
authors.lastname: Baulieu
authors.forename: A
authors.initials: A
authors.lastname: Robier
authors.forename: L
authors.initials: L
authors.lastname: Pourcelot
authors.forename: P
authors.initials: P
authors.lastname: Beutter
mesh_terms: D000161:Acoustic Stimulation; D001303:Auditory Cortex / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000502:physiology; D002560:Cerebrovascular Circulation / Q000502:physiology*; D006801:Humans; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime