Interrelationship between hypersensitivity to soybean proteins and growth performance in early-weaned pigs.
The objective of this growth trial was to determine the interrelationship between immunological criteria, gut morphology, and performance of starter pigs fed soybean proteins processed by different methods. One hundred twenty-five pigs were orally infused with 6 g/d of either dried skim milk, soybean meal (48% CP), soy protein concentrate, extruded soy protein concentrate, or experimental soy protein concentrate from 7 to 11 d of age and then fed a diet containing the same protein sources from weaning (d 21) to 35 d of age. All pigs were fed a corn-soybean meal diet containing 10% dried whey, 1.25% lysine, and 3% soybean oil for the remaining 21 d of the experiment. Xylose absorption and anti-soy immunoglobulin G (IgG) titers were measured on d 6 postweaning, and skin-fold thickness after intradermal injection of protein extracts was measured on d 7 postweaning. A total of 25 pigs (five pigs/treatment) was euthanatized on d 7 postweaning. Villus height and crypt depth from duodenum samples were measured. These measurements were obtained to elucidate a relationship between the hypersensitivity responses to soybean products and growth performance of baby pigs. Pigs fed diets containing soybean meal had a lower (P less than .05) rate of gain (d 0 to 14) and villus height, higher (P less than .01) serum anti-soy IgG titers, and increased skin-fold thickness (d 6 and 7 postweaning) after intradermal injection compared with those fed dried skim milk. Pigs fed other soy proteins also had lower ADG from d 0 to 14 postweaning; however, pigs fed moist extruded soy protein concentrate tended (P less than .09) to have higher ADG and improved feed utilization when compared with pigs fed soybean meal (d 0 to 14).(ABSTRACT TRUNCATED AT 250 WORDS)
Li
D F
DF
Kansas State University, Manhattan 66506.
Nelssen
J L
JL
Reddy
P G
PG
Blecha
F
F
Klemm
R
R
Goodband
R D
RD
D000821:Animal Feed / Q000009:adverse effects*; D000818:Animals; D001419:Bacteria / Q000254:growth & development; D015169:Colony Count, Microbial; D004755:Enterobacteriaceae / Q000254:growth & development; D004797:Enzyme-Linked Immunosorbent Assay; D005512:Food Hypersensitivity / Q000503:physiopathology / Q000662:veterinary*; D007074:Immunoglobulin G / Q000097:blood; D007421:Intestine, Small / Q000382:microbiology / Q000473:pathology; D008871:Microvilli / Q000473:pathology; D014674:Plant Proteins, Dietary / Q000009:adverse effects* / Q000276:immunology; D030262:Soybean Proteins; D013025:Glycine max / Q000009:adverse effects*; D013552:Swine; D013553:Swine Diseases / Q000503:physiopathology*; D014886:Weaning; D015430:Weight Gain
D007074:Immunoglobulin G; D014674:Plant Proteins, Dietary; D030262:Soybean Proteins