title: A catheter-based enzyme-coupled electrode for measurement of lactate.
abstract: An enzyme-coupled electrode was incorporated into a catheter to measure the concentration of lactate solutions. The sensor output was found to be linearly dependent on the lactate concentration. The average nonlinearity over a sample of nine catheters was 5.88% full scale. Hysteresis for the device was low, with an average of 4.54% full scale. Preliminary results indicate that in-vivo measurements may be possible, which are not possible with other lactate measurement methods.
authors.affiliation: Department of Electrical and Computer Engineering, Rose-Hulman Institute of Technology, Terre Haute, IN 47803.
authors.forename: R I
authors.initials: RI
authors.lastname: Waite
authors.forename: L R
authors.initials: LR
authors.lastname: Waite
authors.forename: S P
authors.initials: SP
authors.lastname: Lim
authors.forename: C
authors.initials: C
authors.lastname: Spieker
mesh_terms: D015374:Biosensing Techniques; D002404:Catheterization / Q000295:instrumentation; D004867:Equipment Design; D006801:Humans; D007773:Lactates / Q000097:blood*; D019344:Lactic Acid
chemical_list: D007773:Lactates; D019344:Lactic Acid