Relevance of the rodent model to human aging studies.
Rodents have proven to be a useful general model for aging research. Although they are not necessarily appropriate for the study of such specific human age-associated diseases as atherosclerosis, rodents have provided the basis for important age-related findings in many diverse areas, including nutrition, behavior, immunology, physiology, oncology, biochemistry, and neurobiology. Contributions in these areas are briefly reviewed.
Hazzard
D G
DG
Office of Resource Development, National Institute on Aging, Bethesda, MD 20892.
D000375:Aging / Q000502:physiology*; D000818:Animals; D006801:Humans; D008954:Models, Biological; D012377:Rodentia / Q000502:physiology*