Incidence of bronchopulmonary dysplasia, growth failure, and pulmonary dysfunction assessed by clinical scoring.
A clinical scoring system was used to determine retrospectively whether the severity of bronchopulmonary dysplasia (BPD) in 67 preterm infants at 21 to 27 days of age would predict the need for home supplemental oxygen or growth retardation (weight less than 5th percentile at 12 months of age). The scoring system was composed of five variables, including fractional inspiratory oxygen, partial pressure of CO2, respiratory rate, chest retractions, and growth rate. The score did not predict the need for home supplemental oxygen or growth retardation (P = .87 and .79, respectively); in contrast, the number of hours of oxygen greater than 80% was significantly correlated with home O2 use (P = .0001) and growth retardation at 1 year of age (P = .013). Since there is no simple predictive score that can be used to determine the functional severity of BPD, each at-risk infant must be clinically evaluated for the degree of pulmonary dysfunction, the need for O2 supplementation, and other supportive pulmonary care prior to discharge.
Ariagno
R L
RL
Department of Pediatrics, Stanford University School of Medicine, CA 94305.
Fulroth
R
R
Baldwin
R B
RB
Glotzbach
S F
SF
D001724:Birth Weight; D001997:Bronchopulmonary Dysplasia / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology; D005183:Failure to Thrive / Q000453:epidemiology*; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007230:Infant, Low Birth Weight / Q000254:growth & development; D007231:Infant, Newborn; D007234:Infant, Premature / Q000254:growth & development; D008168:Lung / Q000503:physiopathology; D010100:Oxygen / Q000097:blood; D010102:Oxygen Inhalation Therapy; D011379:Prognosis; D012119:Respiration; D012121:Respiration, Artificial; D012189:Retrospective Studies; D012720:Severity of Illness Index
D010100:Oxygen