title: [Calcifications after intra-disk injection of triamcinolone hexacetonide in lumbar disk hernia. Evaluation of therapeutical results in 3 years].
abstract: The development of disk or epidural calcifications is a frequent possibility following intra-disk injection of triamcinolone hexacetonide. It was found 10 times in 26 follow-up CT scans obtained 2 to 3 years after the injection. These calcifications are often clinically silent, but they sometimes accompany a recurrence of the initial painful symptomatology. Furthermore, evaluation at 3 years of therapeutic results in a previously published series of patients who had received an intra-disk injection of triamcinolone hexacetonide showed a marked decrease in favourable results (30% vs 67% at 6 months). These two arguments: disappointing long term results and possibility of disk calcifications, are felt by the authors to justify abandoning the technique of triamcinolone hexacetonide by intra-disk injection in the treatment of lumbar disk prolapse.
authors.affiliation: Service de Rhumatologie, C.H.U., Poitiers.
authors.forename: F
authors.initials: F
authors.lastname: Debiais
authors.forename: D
authors.initials: D
authors.lastname: Bontoux
authors.forename: M
authors.initials: M
authors.lastname: Alcalay
authors.forename: P
authors.initials: P
authors.lastname: Vandermarcq
authors.forename: O
authors.initials: O
authors.lastname: Azais
authors.forename: A
authors.initials: A
authors.lastname: Denis
authors.forename: I
authors.initials: I
authors.lastname: Azais
authors.forename: C
authors.initials: C
authors.lastname: Gasquet
mesh_terms: D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use*; D002114:Calcinosis / Q000139:chemically induced* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007404:Intervertebral Disc Chemolysis; D007405:Intervertebral Disc Displacement / Q000188:drug therapy*; D008159:Lumbar Vertebrae; D008297:Male; D008875:Middle Aged; D013122:Spinal Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D014222:Triamcinolone Acetonide / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D014222:Triamcinolone Acetonide; C005900:triamcinolone hexacetonide
vernacular_title: Etude des calcifications apparues après injection intradiscale d'hexacétonide de triamcinolone dans les hernies discales lombaires. Evaluation des résultats thérapeutiques à 3 ans.