title: Conjunctival xerosis, arcus lipoides and Rieger's disease.
abstract: Three generations of a family with conjunctival xerosis, Rieger's anomaly (complete or incomplete) and arcus lipoides are described. The xerosis was found always to be accompanied by a Rieger anomaly, which had sometimes, but not always, been detected before. Independent heredity was not observed. In a number of cases the xerosis was bilateral and localised both temporally and nasally. The combination appears to be a stigma malformationis oculi. Correlation with a temporary vitamin A deficiency in early youth appears possible. At this age in such families caution is advisable in the administration of vitamin A inhibiting medicines such as steroids and neomycine.
authors.affiliation: Department of Ophthalmology, University of Leiden, The Netherlands.
authors.forename: R J
authors.initials: RJ
authors.lastname: de Keizer
mesh_terms: D000015:Abnormalities, Multiple; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber / Q000002:abnormalities*; D001112:Arcus Senilis / Q000235:genetics*; D002648:Child; D003229:Conjunctival Diseases / Q000235:genetics*; D005124:Eye Abnormalities; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree