[Oxidative phosphorylation in liver mitochondria in toxic form of experimental form of influenza].
The effect of free radical processes on the oxidation-phosphorylation activity in the liver of CBA-mice has been studied, using a model of toxic form viral infection. The EPR-spectroscopic and electrochemical methods applied in the study of animals infected with pathogenic form of the influenza virus made it possible to reveal a decrease in the activity of the respiratory chain in mitochondria. This seems likely to be due to accumulation of endogenic nitric oxide in the liver tissue.
Bykova
N O
NO
Gorbunov
N V
NV
Bolgarev
A A
AA
Savina
M V
MV
Ivanova
T I
TI
Egoiants
M A
MA
Vanin
V F
VF
Prozorovskaia
M P
MP
D000818:Animals; D004563:Electrochemistry; D005453:Fluorescence; D005609:Free Radicals; D009980:Influenza A virus / Q000472:pathogenicity; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D008930:Mitochondria, Liver / Q000378:metabolism*; D009976:Orthomyxoviridae Infections / Q000378:metabolism*; D010085:Oxidative Phosphorylation
D005609:Free Radicals
Okislitel'noe fosforilirovanie v mitokhondriiakh pecheni pri toksicheskoĭ forme éksperimental'noĭ grippoznoĭ infektsii.