title: [Evaluation of energy metabolism and physical work capacity of divers for determining the optimal oxygen level during breathing gas mixture under pressure up to 5.1 MPa].
abstract: A complex evaluation of energy metabolism, oxygen-transport function of blood and physical work capacity of aquanauts has been performed during three imitation divings at depths of 400, 450 and 500 m in heliox as a breathing medium. These experiments have shown that optimal levels of partial oxygen pressure in artificial chamber environment are 30-33 kPa at 4.1 MPa, 32-35 kPa at 4.6 MPa and 33-34 kPa at 5.1 MPa. It is established that 24-days exposure of aquanautes to 4.6 MPa and 10-days exposure to 5.1 MPa yield no unfavourable changes of the examined organism functions. The activated lipid exchange in combination with stable carbohydrate catabolism, the elevated levels of oxygen consumption and its partial pressure in blood and transient fluctuations of erythropoiesis activity are interpreted as compensatory responses of diverse organisms under the influence of hyperbaric factors.
authors.forename: V V
authors.initials: VV
authors.lastname: Semko
authors.forename: A A
authors.initials: AA
authors.lastname: Povazhenko
authors.forename: V V
authors.initials: VV
authors.lastname: Krivov
authors.forename: T I
authors.initials: TI
authors.lastname: Ryzhova
authors.forename: S I
authors.initials: SI
authors.lastname: Ganenko
mesh_terms: D000280:Administration, Inhalation; D000328:Adult; D001273:Atmosphere Exposure Chambers; D001274:Atmospheric Pressure; D004242:Diving; D004734:Energy Metabolism / Q000187:drug effects / Q000502:physiology*; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism*; D006371:Helium / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D006931:Hyperbaric Oxygenation; D008297:Male; D008954:Models, Biological; D009326:Naval Medicine; D010100:Oxygen / Q000008:administration & dosage* / Q000494:pharmacology*; D014586:USSR; D014938:Work Capacity Evaluation
chemical_list: D006371:Helium; C038949:heliox; D010100:Oxygen
vernacular_title: Otsenka énergeticheskogo obmena i fizicheskoĭ rabotosposobnosti akvanavtov pri opredelenii optimal'nogo soderzhaniia kisloroda v dykhatel'noĭ gazovoĭ smesi pod davleniem do 5.1 MPa.