title: Sequence comparison between the haemagglutinin-neuraminidase genes of simian, canine and human isolates of simian virus 5.
abstract: The nucleotide sequence of the haemagglutinin-neuraminidase (HN) gene was determined for a simian (W3), human (LN) and two canine (CPI+/CPI-) isolates of simian virus 5 (SV5). A comparison of the predicted amino acid sequences revealed that the human and canine isolates varied from the simian isolate by 1.7% and 2.4% respectively. This lack of significant variation between the HN proteins of the four SV5 isolates suggests that insufficient differences have occurred between isolates to confine them to a specific host.
authors.affiliation: Department of Biochemistry and Microbiology, University of St Andrews, Fife, U.K.
authors.forename: D U
authors.initials: DU
authors.lastname: Baty
authors.forename: J A
authors.initials: JA
authors.lastname: Southern
authors.forename: R E
authors.initials: RE
authors.lastname: Randall
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004279:DNA, Viral; D004285:Dogs; D005814:Genes, Viral; D015707:HN Protein / Q000235:genetics*; D000882:Haplorhini; D006801:Humans; D008969:Molecular Sequence Data; D010252:Paramyxoviridae / Q000235:genetics* / Q000302:isolation & purification; D012689:Sequence Homology, Nucleic Acid; D013045:Species Specificity
chemical_list: D004279:DNA, Viral; D015707:HN Protein