title: Prevalence of calcium oxalate uroliths in miniature schnauzers.
abstract: Epidemiologic data were evaluated from all dogs admitted to the University of Minnesota, Veterinary Teaching Hospital (UMVTH) between June 1981 and November 1989. Of 69,890 admissions, 2,077 were Miniature Schnauzers. Uroliths were retrieved from 63 of the 2,077 Miniature Schnauzers admitted. In 20 of the 63 urolith episodes, calcium oxalate was the predominant mineral identified. By comparison, calcium oxalate uroliths were identified in only 56 of the remaining 67,813 non-Miniature Schnauzer canine admissions. The odds that uroliths from Miniature Schnauzers were composed of calcium oxalate was 11.8 times greater than for other canine breeds evaluated at the UMVTH (95% confidence interval = 6.8 to 20.1). Data also were evaluated from files of uroliths retrieved from dogs and submitted to the Minnesota Urolith Center for quantitative mineral analysis, between June 1981 and November 1989. Of 3,930 uroliths analyzed, 615 (15.6%) uroliths were obtained from Miniature Schnauzers. of the 615 uroliths, 175 (28.4%) were calcium oxalate. By comparison, only 550 (16.6%) of the remaining 3,315 from dogs of breeds other than Miniature Schnauzers were calcium oxalate. The odds that uroliths submitted for analysis were composed of calcium oxalate was 2 times greater for Miniature Schnauzers than for dogs of other breeds (95% confidence interval = 1.6 to 2.4). Calcium oxalate uroliths were retrieved more frequently in males than females. The risk for males developing calcium oxalate uroliths was greater than 3 times the risk for females in both groups of data evaluated. The mean age of all Miniature Schnauzers admitted to the UMVTH with calcium oxalate uroliths was 9 years. Calcium oxalate uroliths were not detected in Miniature Schnauzers younger than 1.7 years.
authors.affiliation: Department of Small Animal Clinical Sciences College of Veterinary Medicine, University of Minnesota, St Paul 55108.
authors.forename: J P
authors.initials: JP
authors.lastname: Lulich
authors.forename: C A
authors.initials: CA
authors.lastname: Osborne
authors.forename: L K
authors.initials: LK
authors.lastname: Unger
authors.forename: J
authors.initials: J
authors.lastname: Sanna
authors.forename: C W
authors.initials: CW
authors.lastname: Clinton
authors.forename: M P
authors.initials: MP
authors.lastname: Davenport
mesh_terms: D000367:Age Factors; D000818:Animals; D001947:Breeding; D002129:Calcium Oxalate / Q000032:analysis*; D004283:Dog Diseases / Q000453:epidemiology* / Q000235:genetics; D004285:Dogs; D005260:Female; D008297:Male; D008910:Minnesota / Q000453:epidemiology; D012307:Risk Factors; D012737:Sex Factors; D014545:Urinary Calculi / Q000737:chemistry / Q000453:epidemiology / Q000235:genetics / Q000662:veterinary*
chemical_list: D002129:Calcium Oxalate