title: Radionuclide limb blood flow in peripheral vascular disease: a review of 1100 measurements.
abstract: Radionuclide limb blood flow measurements using 99Tcm-labelled human serum albumin and a gamma camera have been performed on normal volunteers and on patients with suspected or confirmed peripheral arterial disease. The normal range of flow was found to be 10.0-22.3 ml per 100 ml tissue per min. Flow in the symptomatic legs of patients with arterial disease varied from 9.0 ml per 100 ml tissue per min in mild claudication to less than 1.0 ml per 100 ml tissue per min in rest pain. The technique has been used as an initial screening procedure, to resolve diagnostic problems, to measure objectively the treatment response and to assess patients with critical ischaemia. The results of 1100 measurements are reported and the clinical utility in routine vascular surgical practice is discussed.
authors.affiliation: Department of Medical Physics, St James's University Hospital, Leeds, UK.
authors.forename: A
authors.initials: A
authors.lastname: Parkin
authors.forename: P J
authors.initials: PJ
authors.lastname: Robinson
authors.forename: D
authors.initials: D
authors.lastname: Martinez
authors.forename: D
authors.initials: D
authors.lastname: Wilkinson
authors.forename: R C
authors.initials: RC
authors.lastname: Kester
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging* / Q000628:therapy; D005080:Exercise Test; D005260:Female; D006801:Humans; D007383:Intermittent Claudication / Q000000981:diagnostic imaging / Q000628:therapy; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D012016:Reference Values; D013668:Technetium Tc 99m Aggregated Albumin
chemical_list: D013668:Technetium Tc 99m Aggregated Albumin