title: Loss of expression of the uvomorulin gene in compaction-defective embryonal carcinoma cells.
abstract: The lack of uvomorulin protein in the 6B(NG)C25 subline of H6 embryonal carcinoma cells is due to loss of expression of the uvomorulin gene, without evidence of gross alteration in the gene itself. This suggests that the dominant mutation in 6B(NG)C25 may involve a trans-acting factor involved in the regulation of uvomorulin gene expression.
authors.affiliation: Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205.
authors.forename: D E
authors.initials: DE
authors.lastname: Weng
authors.forename: J W
authors.initials: JW
authors.lastname: Littlefield
mesh_terms: D000818:Animals; D015152:Blotting, Northern; D015139:Blotting, Southern; D015820:Cadherins / Q000235:genetics*; D009154:Mutation; D009693:Nucleic Acid Hybridization; D013724:Teratoma / Q000235:genetics*; D014407:Tumor Cells, Cultured
chemical_list: D015820:Cadherins