Attenuation of carbon dioxide-induced panic after clonazepam treatment.
Ten patients meeting the DSM-III-R criteria for panic disorder were treated with clonazepam. Prior to clonazepam treatment and after a 5-week treatment period, patients underwent a 35% carbon dioxide challenge procedure. Following clonazepam treatment, a significant reduction in carbon dioxide vulnerability was observed.
Pols
H
H
Department of Clinical Psychiatry, State University of Limburg, Maastricht, The Netherlands.
Zandbergen
J
J
de Loof
C
C
Griez
E
E
D000328:Adult; D002245:Carbon Dioxide; D002998:Clonazepam / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010200:Panic / Q000187:drug effects*; D016584:Panic Disorder / Q000188:drug therapy* / Q000523:psychology; D011569:Psychiatric Status Rating Scales
D002245:Carbon Dioxide; D002998:Clonazepam