title: Acute treatment of myasthenia gravis with intranasal neostigmine: clinical and electromyographic evaluation.
abstract: The effectiveness of intranasal neostigmine (9.3-13.8 mg) was tested in 20 subjects with myasthenia gravis, classified as Osserman grades 2A and 2B. In all cases the drug produced significant clinical and electromyographic improvement. No side effects were reported during the treatment.
authors.affiliation: Institute of Neurological Clinic, University of Pisa, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Ricciardi
authors.forename: B
authors.initials: B
authors.lastname: Rossi
authors.forename: M
authors.initials: M
authors.lastname: Nicora
authors.forename: A
authors.initials: A
authors.lastname: Sghirlanzoni
authors.forename: A
authors.initials: A
authors.lastname: Muratorio
mesh_terms: D000281:Administration, Intranasal; D000328:Adult; D000368:Aged; D004576:Electromyography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000188:drug therapy* / Q000503:physiopathology; D009388:Neostigmine / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D009388:Neostigmine