title: Resection of central primary pulmonary artery sarcoma.
abstract: Primary sarcomas of the pulmonary arteries are rare, and the diagnosis is in the majority of the reported cases established postmortem. Surgical resection of these centrally located tumors has been performed either by pneumonectomy and/or local tumor resection. We report on two patients with sarcomas of the central pulmonary arteries who underwent successful resection of the tumor and prosthetic replacement of the arteries under cardiopulmonary bypass. One patient required additional thromboendarterectomy of the right pulmonary artery branches because of secondary thrombus formation. As primary pulmonary artery sarcomas are refractory to both chemotherapy and radiation, surgical resection remains the only means of treatment. The prognosis depends entirely upon resectability, which, if necessary, should be performed with the aid of cardiopulmonary bypass. In this way, lung resection may be avoided.
authors.affiliation: Department of Cardiothoracic and Vascular Surgery, University Clinic of Mainz, FRG.
authors.forename: S
authors.initials: S
authors.lastname: Iversen
authors.forename: U
authors.initials: U
authors.lastname: Hake
authors.forename: W
authors.initials: W
authors.lastname: Schmiedt
authors.forename: H
authors.initials: H
authors.lastname: Jakob
authors.forename: U
authors.initials: U
authors.lastname: Ramp
authors.forename: H
authors.initials: H
authors.lastname: Gabbert
authors.forename: H
authors.initials: H
authors.lastname: Oelert
mesh_terms: D000328:Adult; D002315:Cardiopulmonary Bypass; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011651:Pulmonary Artery / Q000473:pathology / Q000601:surgery*; D012008:Recurrence; D012509:Sarcoma / Q000473:pathology / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D014652:Vascular Diseases / Q000473:pathology / Q000601:surgery