title: [Use of flumazenil to reverse the effects of midazolam in children].
abstract: We have studied the clinical usefulness of Flumazenil to reverse the sedative action of Midazolam in 12 children admitted in a Pediatric Intensive Care Unit. Two groups were established, one treated with individual dose and the other treated with continuous infusion. In four cases the indication of Flumazenil was the reversion of secondary effects and in 8 cases it was elective. The average reversion time was 1.22 +/- 0.42 minutes. Flumazenil is able to reverse immediately the effects of Midazolam.
authors.affiliation: Departamento de Pediatría, Hospital General de Galicia, Clínico Universitario, Santiago de Compostela.
authors.forename: A
authors.initials: A
authors.lastname: Rodríguez Núñez
authors.forename: J M
authors.initials: JM
authors.lastname: Martinón Sánchez
authors.forename: P
authors.initials: P
authors.lastname: Rivas Pumar
authors.forename: I
authors.initials: I
authors.lastname: Martínez Soto
authors.forename: J L
authors.initials: JL
authors.lastname: Relova Quinteiro
authors.forename: J
authors.initials: J
authors.lastname: Peña Guitián
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001007:Anxiety / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D005442:Flumazenil / Q000008:administration & dosage*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage; D007223:Infant; D008874:Midazolam / Q000008:administration & dosage / Q000037:antagonists & inhibitors / Q000627:therapeutic use*
chemical_list: D006993:Hypnotics and Sedatives; D005442:Flumazenil; D008874:Midazolam
vernacular_title: Utilidad del flumazenil para revertir las acciones del midazolam en niños.