title: Inability of cephalothin testing to predict cefprozil susceptibility.
abstract: The 30-micrograms cefprozil disk and the cephalosporin class (30-micrograms cephalothin) disk were compared for their abilities to predict cefprozil susceptibility by agar disk diffusion testing. High error (5.02% major and 14.11% minor) rates were encountered with the cephalothin disk and were most frequently observed for Escherichia coli and Enterococcus faecalis. The cefprozil disks resulted in rates of 0.05% very major, 0% major, and 3.72% minor errors. Thus, the 30-micrograms cefprozil disk is more desirable for predicting cefprozil susceptibility.
authors.affiliation: Department of Microbiology, Pharmaceutical Research Institute, Wallingford, Connecticut 06492.
authors.forename: J
authors.initials: J
authors.lastname: Fung-Tomc
authors.forename: T
authors.initials: T
authors.lastname: Stickle
authors.forename: C
authors.initials: C
authors.lastname: Doyle
authors.forename: E
authors.initials: E
authors.lastname: Huczko
authors.forename: R E
authors.initials: RE
authors.lastname: Kessler
mesh_terms: D002511:Cephalosporins / Q000494:pharmacology*; D002512:Cephalothin / Q000494:pharmacology*; D004755:Enterobacteriaceae / Q000187:drug effects / Q000302:isolation & purification; D013293:Enterococcus faecalis / Q000187:drug effects / Q000302:isolation & purification; D004926:Escherichia coli / Q000187:drug effects / Q000302:isolation & purification; D005069:Evaluation Studies as Topic; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods*; D000097670:Cefprozil
chemical_list: D002511:Cephalosporins; D002512:Cephalothin; D000097670:Cefprozil