Sepsis syndrome. New insights into its pathogenesis and treatment.
Recent insights into the pathogenesis of sepsis and its sequelae have opened up new approaches to treatment. For maximum effectiveness, however, treatment must be given as early as possible in the course of illness--but only to patients who are at high risk of developing shock. The definition of sepsis syndrome outlined in this article provides a method by which to identify such patients before the onset of shock.
Bone
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Rush Medical College, Chicago, Illinois.
D000818:Animals; D016470:Bacteremia / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D012772:Shock, Septic / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D013577:Syndrome