title: Physiology of normal and abnormal synovium.
abstract: Because the synovial lining is a major target organ of rheumatic diseases, it seems logical to seek understanding of those conditions through study of the normal and abnormal physiology of this specialized organ system. This brief review covers some basic principles and recent progress in this area with emphasis on our evolving knowledge of microvascular function.
authors.affiliation: Department of Medicine, University of Washington, Seattle 98195.
authors.forename: P A
authors.initials: PA
authors.lastname: Simkin
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000493:pharmacokinetics; D005122:Exudates and Transudates / Q000378:metabolism; D006801:Humans; D007592:Joint Diseases / Q000378:metabolism / Q000503:physiopathology*; D007596:Joints / Q000378:metabolism / Q000503:physiopathology; D007700:Kinetics; D009038:Motion; D011312:Pressure; D012016:Reference Values; D013583:Synovial Membrane / Q000378:metabolism / Q000502:physiology* / Q000503:physiopathology
chemical_list: D000893:Anti-Inflammatory Agents