title: [The dynamics of the cerebral circulation and of brain functional activity in patients with initial atherosclerotic encephalopathy under the influence of a single intravenous administration of sermion].
abstract: The efficacy of sermion was studied in 41 patients of the middle and elderly ages. The reactive changes in the parameters of the cerebral circulation (the frontomastoidal RhEG), total hemodynamics, frequency-integration characteristics of EEG and visual evoked potentials at the administration of 2 mg and 4 mg of sermion were shown. There are given recommendations for the differential approach to the choice of the drug doses in the elderly persons taking into consideration the parameters of the background reactivity of the CNS and the state of vascular regulation.
authors.forename: A Ia
authors.initials: AIa
authors.lastname: Mints
authors.forename: I N
authors.initials: IN
authors.lastname: Karaban'
authors.forename: A A
authors.initials: AA
authors.lastname: Litvinenko
mesh_terms: D000368:Aged; D000375:Aging / Q000187:drug effects / Q000502:physiology; D001921:Brain / Q000187:drug effects* / Q000503:physiopathology; D002560:Cerebrovascular Circulation / Q000187:drug effects* / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation; D004569:Electroencephalography / Q000187:drug effects / Q000379:methods; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D006801:Humans; D007275:Injections, Intravenous; D002537:Intracranial Arteriosclerosis / Q000188:drug therapy* / Q000503:physiopathology; D008875:Middle Aged; D009530:Nicergoline / Q000008:administration & dosage*; D013997:Time Factors
chemical_list: D009530:Nicergoline
vernacular_title: Dinamika mozgovogo krovoobrashcheniia i funktsional'noĭ aktivnosti mozhga u bol'nykh s nachal'noĭ ateroskleroticheskoĭ éntsefalopatieĭ pod vliianiem odnokratnogo vnutrivennogo vvedeniia sermiona.