Prognostic value of cerebrospinal fluid protein content and leukocyte count in infants and childhood bacterial meningitis.
Seventy infants and children with bacterial meningitis were studied. All children were treated with ampicillin and chloramphenicol. A significant increase in the cerebrospinal fluid protein concentration determined on admission was found in patients who died as compared to those who survived (P less than 0.05). However, no difference was observed between the admission CSF leukocyte count in those patients who died versus those who survived. From this study, it can be concluded that the determination of CSF protein level on admission is an easy, fast and reliable method that can be used to predict clinical outcomes in acute bacterial meningitis.
Shaaban
S Y
SY
Department of Pediatrics, Ain Shams University, US Naval Medical Research Unit No. 3, Cairo, Egypt.
Girgis
N I
NI
Mansour
M M
MM
Yassin
H A
HA
Shikely
K M
KM
D000293:Adolescent; D002555:Cerebrospinal Fluid / Q000166:cytology*; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D004534:Egypt / Q000453:epidemiology; D005069:Evaluation Studies as Topic; D005260:Female; D006782:Hospitals, Special; D006801:Humans; D007223:Infant; D007958:Leukocyte Count; D008297:Male; D016920:Meningitis, Bacterial / Q000134:cerebrospinal fluid* / Q000382:microbiology / Q000401:mortality; D011237:Predictive Value of Tests; D011379:Prognosis
D002556:Cerebrospinal Fluid Proteins