[Action of an enkephalinase blocker on the effect of acupuncture in acupuncture sensitive and resistant rabbits].
In unanaesthetized acupuncture-sensitive rabbit d-phenylalanine injection didn't change the EP in response to tooth pulp electrostimulation, but prolonged the analgetic effect of auriculo-acupuncture stimulation 15 Hz expressed by decreasing of the amplitude of N1P2 component EP. In acupuncture-resistant rabbit d-phenylalanine injection induced analgetic effect which was enhanced and prolonged by auriculo-acupuncture stimulation. It's suggested that the recovery of pain sensibility after acupuncture analgesia is determined by enkephalinase's mechanism activation which is activated permanently in acupuncture-resistant rabbits.
Kaliuzhnyĭ
L V
LV
Kozlov
A Iu
AIu
D015667:Acupuncture Analgesia; D000818:Animals; D004558:Electric Stimulation; D008297:Male; D015260:Neprilysin / Q000037:antagonists & inhibitors*; D010147:Pain Measurement; D010649:Phenylalanine / Q000494:pharmacology*; D011817:Rabbits
D010649:Phenylalanine; D015260:Neprilysin
Vliianie blokatora énkefalinazy na éffekty akupunktury u akupunkturo-chuvstvitel'nykh i rezistentnykh krolikov.