[Pathogenesis of arterial hypertension in diabetes mellitus].
To investigate pathogenesis of arterial hypertension in diabetes mellitus, the authors measured parameters of central and peripheral hemodynamics, basal renin levels, angiotensin, aldosterone, kallikrein-kinin system. The results were analysed with regard to hypertension type: essential (EH), atherosclerotic (AH) and nephrogenic (NH). Hypokinetic circulation, defected vascular elasticity, activation of renin-angiotensin-aldosterone system and hypoactivity of kallikrein-kinin system were characteristic of EH and AH. Most pronounced changes in peripheral hemodynamics and hypoactivity of depressor kallikrein-kinin system were seen in NH.
Zubkova
S T
ST
Epshteĭn
E V
EV
Bulat
O V
OV
Bezverkhaia
T P
TP
Skrobonskaia
N A
NA
D000328:Adult; D000368:Aged; D003920:Diabetes Mellitus / Q000503:physiopathology*; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology; D005260:Female; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D016234:Kallikrein-Kinin System / Q000502:physiology; D008297:Male; D008875:Middle Aged; D012084:Renin-Angiotensin System / Q000502:physiology
K patogenezu arterial'noĭ gipertenzii pri sakharnom diabete.