Correlation between the level of IgA and Pneumocystis carinii infection.
Sputum examination for detection of P. carinii pneumonia (PCP) can be substituted for more invasive techniques. There was a significant correlation between PCP and the increased level of IgA in serum (P less than 0.01) and sputum. The increase in IgA level in sputum was much more higher than that in the serum. This supports the concept that local antibody formation by the lung may have a more important role in the immune and inflammatory response to P. carinii.
el-Sebai
M M
MM
Department of Parasitology, Faculty of Medicine, Ain Shams University, Abbassia, Cairo.
el-Helaly
S M
SM
Aly
A G
AG
Faris
L
L
D006801:Humans; D007070:Immunoglobulin A / Q000097:blood*; D011010:Pneumocystis / Q000302:isolation & purification*; D011020:Pneumonia, Pneumocystis / Q000175:diagnosis / Q000276:immunology*; D013183:Sputum / Q000276:immunology / Q000382:microbiology*
D007070:Immunoglobulin A