title: [Essential thrombocythemia. Therapy with interferon alfa].
abstract: A clinical case of essential thrombocythaemia is presented to demonstrate good therapeutic response to subcutaneous Alpha-2b Interferon in a dosage of 3 x 10(6) units, three times a week. Based on this case and on a literature research we propose that Alpha-2b Interferon is a legitimate alternative to alkylating agents or radioactive phosphorus (32P), showing identical efficacy and less Leukemogen effect.
authors.affiliation: Serviço de Medicina Interna, Hospital Sa. Cruz, Carnaxide.
authors.forename: L
authors.initials: L
authors.lastname: Lebre
authors.forename: A
authors.initials: A
authors.lastname: Sousa
authors.forename: J
authors.initials: J
authors.lastname: Sampaio
authors.forename: L
authors.initials: L
authors.lastname: Novais
authors.forename: E
authors.initials: E
authors.lastname: Júnior
authors.forename: R
authors.initials: R
authors.lastname: Coelho
authors.forename: J
authors.initials: J
authors.lastname: Simões
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use*; D008875:Middle Aged; D013920:Thrombocythemia, Essential / Q000628:therapy*
chemical_list: D016898:Interferon-alpha
vernacular_title: Trombocitemia essencial. Terapêutica com alfa interferão.