title: 24-hour survival of autotransfused red cells in elective aortic surgery: a comparison of two intraoperative autotransfusion systems.
abstract: Twelve patients undergoing elective aortic surgery had intraoperative autotransfusion using either the Haemonetics Cell Saver or the Solcotrans device. The 24-h post-transfusion survival of the patients' preoperative red cells, labelled with indium-111, was compared with the survival of salvaged red cells labelled with chromium-51. A correction coefficient for the instability of the indium-111 label was calculated from the study of red cell survival in six healthy volunteers. There was no significant difference in the volume of circulating red cells measured using each isotope, indicating that extensive early destruction of the autotransfused red cells does not occur. The percentage survival of autotransfused red cells at 24 h was similar to that of the red cells that had not undergone salvage. Both devices were comparable with respect to the effects of cell salvage on the 24-h survival rate of autotransfused red cells.
authors.affiliation: Department of Surgery, St. James's University Hospital, Leeds, UK.
authors.forename: P
authors.initials: P
authors.lastname: Kent
authors.forename: S
authors.initials: S
authors.lastname: Ashley
authors.forename: P J
authors.initials: PJ
authors.lastname: Thorley
authors.forename: A
authors.initials: A
authors.lastname: Shaw
authors.forename: A
authors.initials: A
authors.lastname: Parkin
authors.forename: R C
authors.initials: RC
authors.lastname: Kester
mesh_terms: D001018:Aortic Diseases / Q000601:surgery*; D001804:Blood Transfusion, Autologous / Q000379:methods*; D002860:Chromium Radioisotopes; D004905:Erythrocyte Aging / Q000502:physiology*; D017707:Erythrocyte Transfusion; D004911:Erythrocyte Volume / Q000502:physiology; D005260:Female; D006801:Humans; D007205:Indium Radioisotopes; D008297:Male
chemical_list: D002860:Chromium Radioisotopes; D007205:Indium Radioisotopes