title: Gram-negative bacterial pneumonia with secondary aspergillosis in an AIDS patient.
abstract: A 40-year-old, HIV-infected female patient received antibiotic treatment for a urinary tract infection. After the initial success of therapy and a symptom-free period, she developed pneumonia with septic shock and adult respiratory distress syndrome (ARDS). In spite of intensive care and respirator therapy with positive end-expiratory pressure (PEEP), she died of infectious toxic shock. Autopsy findings showed relapsing, gram-negative, bacterial pneumonia (morphologically compatible with Klebsiella pneumonia) and secondary, invasive aspergillosis. The pathogenesis and epidemiology of these unusual complications of AIDS are discussed.
authors.affiliation: III. Medizinische Klinik, Fakultät für Klinische Medizin Mannheim, Universität Heidelberg.
authors.forename: K
authors.initials: K
authors.lastname: Bonatz
authors.forename: A
authors.initials: A
authors.lastname: Weiss
authors.forename: R
authors.initials: R
authors.lastname: Hehlmann
authors.forename: H P
authors.initials: HP
authors.lastname: Assmus
authors.forename: M
authors.initials: M
authors.lastname: Heine
mesh_terms: D000386:AIDS-Related Complex / Q000175:diagnosis / Q000473:pathology; D000328:Adult; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000175:diagnosis* / Q000473:pathology; D001232:Aspergillus fumigatus / Q000648:ultrastructure; D001921:Brain / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D007710:Klebsiella Infections / Q000175:diagnosis* / Q000473:pathology; D008168:Lung / Q000473:pathology; D008169:Lung Abscess / Q000473:pathology; D009894:Opportunistic Infections / Q000175:diagnosis* / Q000473:pathology; D011014:Pneumonia / Q000175:diagnosis* / Q000473:pathology; D012128:Respiratory Distress Syndrome / Q000473:pathology