Mapping of human chromosome 5 microsatellite DNA polymorphisms.
Thirteen moderately to highly informative microsatellite DNA polymorphisms based on (dC-dA)n.(dG-dT)n repeats were mapped to segments of human chromosome 5 using both linkage analysis and a panel of somatic cell hybrids which contained rearranged chromosomes. The markers were distributed throughout most of the length of the chromosome from the regions p15.3-p15.1 to q33.3-qter. Maps of the sites of meiotic recombination within the reference families proved particularly useful for the purpose of integrating new polymorphisms into the existing linkage map.
Weber
J L
JL
Marshfield Medical Research Foundation, Wisconsin 54449.
Polymeropoulos
M H
MH
May
P E
PE
Kwitek
A E
AE
Xiao
H
H
McPherson
J D
JD
Wasmuth
J J
JJ
D001483:Base Sequence; D002874:Chromosome Mapping; D002895:Chromosomes, Human, Pair 5; D003001:Cloning, Molecular; D004276:DNA, Satellite / Q000235:genetics*; D005260:Female; D008040:Genetic Linkage / Q000235:genetics; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D011995:Recombination, Genetic / Q000235:genetics
D004276:DNA, Satellite