Evaluation of lumbar bone mineral density by dual energy x-ray absorptiometry.
Using dual-energy x-ray absorptiometry (DEXA), the lumbar spinal bone mineral density (BMD) in 49 Japanese children with or without metabolic bone disease (MBD) was determined. The following results were obtained: (a) The normal data for healthy Caucasians (J Clin Endocrinol Metab 1990; 70: 1330-1333) appear to be applicable to Japanese children; (b) BMD was normal in patients with congenital hydronephrosis with normal renal function; (c) One patient with congenital renal failure and one with Lowe syndrome had low BMD, but the MBD in the former improved markedly with peritoneal dialysis; (d) A reduced BMD was found in patients treated with long-term steroids, probably because of decreased turnover of bone; (e) A reduction in BMD was pronounced in preterm infants during the first few months of life. In conclusion, DEXA is a useful method of bone densitometry in MBD in children.
Tsukahara
H
H
Department of Pediatrics, Fukui Medical School, Japan.
Nakashima
T
T
Yoshimoto
M
M
Kuriyama
M
M
Shigematsu
Y
Y
Hayashi
S
S
Haruki
S
S
Ishii
Y
Y
Sudo
M
M
D015502:Absorptiometry, Photon; D000293:Adolescent; D044466:Asian People; D015519:Bone Density; D001851:Bone Diseases, Metabolic / Q000000981:diagnostic imaging* / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D007564:Japan; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging*; D008297:Male; D010024:Osteoporosis / Q000139:chemically induced / Q000000981:diagnostic imaging; D012016:Reference Values; D013256:Steroids / Q000009:adverse effects
D013256:Steroids