title: Thyroid hormones and testis development: a model system for increasing testis growth and sperm production.
abstract: In conclusion, the unique transient hypothyroidism system described here provides a noninvasive means by which testicular size and sperm production can be increased to unprecedented degrees. This system may be useful as a model for understanding the factors which regulate testicular growth and the eventual size that the testes attain, as well as the factors which normally establish and then maintain the amount of sperm produced by an animal.
authors.affiliation: Department of Veterinary Biosciences, University of Illinois, Urbana 61801.
authors.forename: P S
authors.initials: PS
authors.lastname: Cooke
mesh_terms: D000818:Animals; D005298:Fertility / Q000502:physiology; D008297:Male; D008954:Models, Biological; D011441:Propylthiouracil; D051381:Rats; D013091:Spermatogenesis / Q000502:physiology*; D013737:Testis / Q000166:cytology / Q000254:growth & development*; D013739:Testosterone / Q000378:metabolism; D013963:Thyroid Hormones / Q000502:physiology*
chemical_list: D013963:Thyroid Hormones; D013739:Testosterone; D011441:Propylthiouracil