Epidemiological associations between Mycoplasma hyopneumoniae and Actinobacillus pleuropneumoniae antibody titers and lung lesions in Prince Edward Island swine herds.
A survey of anteroventral (AV) lung lesions, pleuritis and serology for Mycoplasma hyopneumoniae (MH) and Actinobacillus pleuropneumoniae (AP) was conducted on a minimum of 25 slaughter hogs from each of 18 randomly sampled Prince Edward Island farms (producing over 1,000 market hogs per year). The data were analyzed to evaluate the potential role of these two agents as risk factors for the two conditions, using crude and multivariable techniques, as well as individual and herd data. Anteroventral lung lesions were present in 50.5% of hogs at slaughter, and pleuritis was present in 15.4% of the hogs. Least squares multivariable regression was used to analyze the simultaneous ability of MH, AP and MH/AP interaction to predict the herd prevalence of AV lung lesions. Only MH was associated with AV lung lesions (p = 0.035). In spite of this statistical significance, MH accounted for only 53% of the herd variation in prevalence of lung lesions (R2 = 0.529). As well, some herds maintained very low levels of lung lesions despite moderate (up to 30%) prevalence of MH. Discrepancies between the analytic techniques suggested herd-level factors play an important role in the development of lung lesions. Pleuritis did not appear to be associated with either of the agents studied (p = 0.478).
Van Til
L D
LD
Department of Health Management, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown.
Dohoo
I R
IR
Morley
R S
RS
D000189:Actinobacillus Infections / Q000453:epidemiology / Q000662:veterinary*; D016977:Actinobacillus pleuropneumoniae / Q000276:immunology*; D000704:Analysis of Variance; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D016018:Least-Squares Analysis; D008168:Lung / Q000473:pathology*; D009174:Mycoplasma / Q000276:immunology; D009175:Mycoplasma Infections / Q000453:epidemiology / Q000662:veterinary*; D010998:Pleurisy / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary; D011014:Pneumonia / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary; D015995:Prevalence; D011325:Prince Edward Island / Q000453:epidemiology; D012307:Risk Factors; D012984:Software; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology*
D000907:Antibodies, Bacterial