title: Solitary brain metastasis: radiosurgery in lieu of microsurgery in 32 patients.
abstract: Thirty-two consecutive patients with 34 small brain metastases underwent boost stereotactic radiosurgery using the first North American Gamma Unit between May 1988 and July 1990. The majority of tumors (n = 24; 71%) were considered resistant to conventional, fractionated irradiation (malignant melanoma, n = 13; non-small cell lung carcinoma, n = 7; renal cell carcinoma, n = 4). During the follow-up period (median = 10 months; range = 1.5-15 months) no patient suffered a complication of radiosurgical treatment, and no patient died from a radiosurgically-treated metastasis. Shrinkage or growth-arrest was documented in 20 of 23 patients (87%) available for follow-up. Median survival after treatment was 10 months.
authors.affiliation: Department of Neurologic Surgery, Mayo Clinic/Mayo Medical School.
authors.forename: R J
authors.initials: RJ
authors.lastname: Coffey
authors.forename: J C
authors.initials: JC
authors.lastname: Flickinger
authors.forename: L D
authors.initials: LD
authors.lastname: Lunsford
authors.forename: D J
authors.initials: DJ
authors.lastname: Bissonette
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001164:Arteriovenous Fistula / Q000601:surgery*; D001165:Arteriovenous Malformations / Q000601:surgery*; D002340:Carotid Artery Diseases / Q000601:surgery*; D002426:Cavernous Sinus / Q000002:abnormalities / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis; D016634:Radiosurgery / Q000295:instrumentation*; D013238:Stereotaxic Techniques / Q000295:instrumentation*