Anti-human red cell monoclonal antibodies produced by macaque-mouse heterohybridomas.
Eight monoclonal antibodies (Mabs) against human red cells were produced by macaque-mouse heterohybridomas. All Mabs uniformly reacted with all human red blood cells tested, but only some agglutinated the red cells of anthropoid apes occasionally detecting intraspecies polymorphisms. None was reactive with blood of Old and New World monkeys. One of the Mabs recognized the Vc antigen of the chimpanzee V-A-B-D system, the homologue of the human M-N blood group system.
Blancher
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Laboratoire d'Anthropologie Physique, Collège de France, Paris.
Socha
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D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis*; D001789:Blood Group Antigens; D004912:Erythrocytes / Q000276:immunology*; D006801:Humans; D006825:Hybridomas; D008214:Lymphocytes / Q000276:immunology*; D008253:Macaca mulatta / Q000097:blood*; D008254:Macaca nemestrina / Q000097:blood*; D008297:Male; D051379:Mice; D011323:Primates / Q000097:blood
D000911:Antibodies, Monoclonal; D001789:Blood Group Antigens