Polymeric gastrointestinal MR contrast agents.
Combining either paramagnetic (gadolinium chelates) or superparamagnetic (ferrite) contrast agents with polymers such as polyethylene glycol or cellulose, or with simple sugars such as dextrose, results in mixtures that exhibit improved T1 and/or T2 relaxivity compared with that of the contrast agent alone. It is suggested that the addition of such inexpensive and nontoxic polymers or saccharides may improve the effectiveness and decrease the cost of enteric contrast agents.
Tilcock
C
C
Department of Radiology, University of British Columbia, Vancouver, Canada.
Unger
E C
EC
Ahkong
Q F
QF
Fritz
T
T
Koenig
S H
SH
Brown
R D
RD
D002482:Cellulose; D003287:Contrast Media; D004064:Digestive System / Q000033:anatomy & histology*; D005290:Ferric Compounds; D005682:Gadolinium; D005947:Glucose; D006801:Humans; D066298:In Vitro Techniques; D008279:Magnetic Resonance Imaging; D011092:Polyethylene Glycols
D003287:Contrast Media; D005290:Ferric Compounds; C001215:ferrite; D011092:Polyethylene Glycols; D002482:Cellulose; D005682:Gadolinium; D005947:Glucose