title: Octamania: the POU factors in murine development.
abstract: Much effort has been directed towards the investigation of regulatory processes in the early mouse embryo. Several multigene families of developmental control genes have been identified. The POU family is a group of related transcription factors containing a particular type of bipartite DNA-binding domain. Members of this family show distinct expression patterns during embryonic development. Two members, Oct-4 and Oct-6, are expressed as early as in the preimplantation embryo and thus may regulate early events of murine development.
authors.affiliation: Max-Planck Institute of Biophysical Chemistry, Department of Molecular Cell Biology, Göttingen, FRG.
authors.forename: H R
authors.initials: HR
authors.lastname: Schöler
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D004268:DNA-Binding Proteins / Q000235:genetics; D005314:Embryonic and Fetal Development / Q000235:genetics*; D006801:Humans; D051379:Mice; D008969:Molecular Sequence Data; D050814:Octamer Transcription Factor-3; D050816:Octamer Transcription Factor-6; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
chemical_list: D004268:DNA-Binding Proteins; D050814:Octamer Transcription Factor-3; C494178:POU3F1 protein, human; C494173:POU5F1 protein, human; C494180:Pou3f1 protein, mouse; C494174:Pou5f1 protein, mouse; D014157:Transcription Factors; D050816:Octamer Transcription Factor-6