title: Early re-extension of necrosis in myocardial infarction. Favouring factors and prognosis in the first months of evolution.
abstract: To determine the risk of myocardial necrosis re-extension (RN) appearance in the first month of evolution of myocardial infarction (MI) confirmed clinically, by ECG, and enzymatically, 262 patients (mean age 64.5 years, 64.6% males) were studied. The incidence of RN was found present in 67 patients (25.6%). A complex statistical analysis (stepwise regression analysis) of the variables presented by the patients (clinical, ECG and laboratory) showed that only 5 variables are important in the determination of the risk of RN namely: nontransmural localization of initial necrosis, atrial fibrillation, past history of angor pectoris, prolonged pain at onset and presence of idioventricular rhythm. The introduction of these 5 variables in a multiple regression equation will allow the distribution of patients, already at entry, in subgroups of risk of re-extension necrosis within the first month of MI evolution thus allowing a more careful management of disease.
authors.affiliation: Medical Clinic of Griviţa Hospital, Bucharest, Romania.
authors.forename: I
authors.initials: I
authors.lastname: Guţiu
authors.forename: T G
authors.initials: TG
authors.lastname: Banu
authors.forename: I
authors.initials: I
authors.lastname: Greceanu
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000453:epidemiology / Q000401:mortality; D009206:Myocardium / Q000473:pathology*; D009336:Necrosis; D011379:Prognosis; D012008:Recurrence; D012044:Regression Analysis; D012307:Risk Factors; D012737:Sex Factors; D013997:Time Factors