title: Increased frequency of chromosomal aberrations in railroad car painters.
abstract: The purpose of this study was to determine if exposure to paints and solvents contributes to chromosomal alterations in occupationally exposed individuals. A total of 25 male railroad and underground railroad car painters were studied. This group had a mean age of 32.7 y and a mean exposure time of 5.2 y. The results were compared with those obtained for 25 healthy (unexposed) males. The scoring of structural chromosome aberrations clearly revealed an increase in the number of all types of aberrations considered in the population of painters. This suggests that exposure to a combination of chemicals may increase genotoxicity in industrial workers.
authors.affiliation: Depto. Morfología Escuela Nacional de Ciencias Biológicas México.
authors.forename: A
authors.initials: A
authors.lastname: Piña-Calva
authors.forename: E
authors.initials: E
authors.lastname: Madrigal-Bujaidar
authors.forename: M V
authors.initials: MV
authors.lastname: Fuentes
authors.forename: P
authors.initials: P
authors.lastname: Neria
authors.forename: C
authors.initials: C
authors.lastname: Pérez-Lucio
authors.forename: N M
authors.initials: NM
authors.lastname: Vélez-Zamora
mesh_terms: D000328:Adult; D002842:Chromatids / Q000187:drug effects; D002869:Chromosome Aberrations; D006801:Humans; D007221:Industry; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D010150:Paint / Q000009:adverse effects*; D011890:Railroads; D012997:Solvents / Q000009:adverse effects*
chemical_list: D012997:Solvents