title: [A new Soviet allergen made from bee venom for the specific diagnosis of allergic reactions to bee stings].
abstract: Overall 46 patients with allergic reactions to bee stings were examined. As a result of making skin prick, scarification and intracutaneous tests with an allergen from bee venom, allergy to bee stings was revealed in all the 46 patients, whereas only 37 patients responded to an allergen from the bee body. Specific IgE-antibodies using RAST were detected in 29 out of 31 patients. All the 29 patients had positive skin tests with an allergen from bee venom and only 22 with an allergen from the bee body. Specific histamine release was detected in all 13 patients examined by means of the indicated test. 100% coincidence was recorded with the results of intracutaneous tests with an allergen from bee venom. Only 11 out of the 13 patients had positive intracutaneous tests with an allergen from the bee body. Thus, the new Soviet allergen obtained from bee venom is effective in the diagnosis of allergy in response to bee stings.
authors.forename: S M
authors.initials: SM
authors.lastname: Shvets
authors.forename: I S
authors.initials: IS
authors.lastname: Gushchin
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Poroshina
authors.forename: V G
authors.initials: VG
authors.lastname: Chitaeva
authors.forename: S M
authors.initials: SM
authors.lastname: Titova
authors.forename: E B
authors.initials: EB
authors.lastname: Romanova
authors.forename: N V
authors.initials: NV
authors.lastname: Korneva
authors.forename: B N
authors.initials: BN
authors.lastname: Orlov
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Lebedin
mesh_terms: D000293:Adolescent; D000328:Adult; D000485:Allergens / Q000302:isolation & purification; D000818:Animals; D001514:Bee Venoms; D001516:Bees / Q000276:immunology; D002648:Child; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis*; D007299:Insect Bites and Stings / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012882:Skin Tests
chemical_list: D000485:Allergens; D001514:Bee Venoms
vernacular_title: Novyĭ otechestvennyĭ allergen iz iada pchel dlia spetsificheskoĭ diagnostiki allergicheskikh reaktsiĭ na uzhaleniia pchelami.