title: Streptococcal lid necrosis in previously healthy children.
abstract: Fulminant preseptal eyelid cellulitis developed in two previously healthy children, aged 17 months and 8 years, following minor trauma. Despite appropriate intravenous antibiotic therapy, lid necrosis with ulceration developed in both patients. In both cases group A beta-hemolytic Streptococcus was the causative agent. Spontaneous granulation of the ulcerated areas resulted in cicatricial defects, which in one case may require surgical correction. Neither child had a past history of susceptibility to infection. Group A beta-hemolytic Streptococcus has been known to cause lid gangrene, but almost all previously documented cases occurred in debilitated or elderly patients.
authors.affiliation: Department of Ophthalmology, McGill University, Montreal, PQ.
authors.forename: L
authors.initials: L
authors.lastname: Stone
authors.forename: F
authors.initials: F
authors.lastname: Codère
authors.forename: S A
authors.initials: SA
authors.lastname: Ma
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002481:Cellulitis / Q000188:drug therapy / Q000382:microbiology*; D002648:Child; D005141:Eyelid Diseases / Q000188:drug therapy / Q000382:microbiology*; D005143:Eyelids / Q000293:injuries* / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009336:Necrosis; D013290:Streptococcal Infections / Q000188:drug therapy; D013297:Streptococcus pyogenes; D014456:Ulcer
chemical_list: D000900:Anti-Bacterial Agents