title: [Methotrexate and psoriasis].
abstract: Methotrexate is effective in the treatment of severe psoriasis. If recommended guidelines are strictly followed the drug, administered in low doses, is not dangerous. The main adverse effect is cumulative hepatotoxicity. Hematologic toxicity occurs especially if other medications are associated.
authors.affiliation: Service de dermatologie, hôpital Henri-Mondor, Créteil.
authors.forename: I
authors.initials: I
authors.lastname: Bournerias
mesh_terms: D000075202:Contraindications; D008727:Methotrexate / Q000009:adverse effects / Q000627:therapeutic use*; D011565:Psoriasis / Q000188:drug therapy*
chemical_list: D008727:Methotrexate
vernacular_title: Méthotrexate et psoriasis.