The 5-HT2 serotonin receptor gene Htr-2 is tightly linked to Es-10 on mouse chromosome 14.
Clones coding for the 5-HT2 serotonin receptor were isolated from rat brain cDNA libraries. Using one of the cDNA clones as the probe, mouse genomic DNAs from intersubspecific backcrosses were analyzed by Southern blot hybridization for a restriction fragment length polymorphism. The 5-HT2 serotonin receptor gene, Htr-2, was mapped to mouse Chromosome 14 and is closely linked with the marker Es-10.
Liu
J
J
Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis 46202.
Chen
Y
Y
Kozak
C A
CA
Yu
L
L
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015139:Blotting, Southern; D003433:Crosses, Genetic; D004247:DNA; D005260:Female; D008040:Genetic Linkage; D005819:Genetic Markers / Q000235:genetics; D008297:Male; D051379:Mice; D008969:Molecular Sequence Data; D051381:Rats; D011985:Receptors, Serotonin / Q000235:genetics*
D005819:Genetic Markers; D011985:Receptors, Serotonin; D004247:DNA