Interferon type I and II antagonism: a novel regulatory mechanism of indoleamine dioxygenase induction in human peripheral blood monocytes and peritoneal macrophages.
Ozaki
Y
Y
University of Wisconsin Clinical Cancer Center, Madison 53792.
Borden
E C
EC
Smalley
R V
RV
Brown
R R
RR
D019307:1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; D004790:Enzyme Induction / Q000187:drug effects; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000494:pharmacology*; D016899:Interferon-beta / Q000494:pharmacology*; D007371:Interferon-gamma / Q000494:pharmacology*; D007546:Isoquinolines / Q000494:pharmacology; D007963:Leukocytes, Mononuclear / Q000201:enzymology*; D008264:Macrophages / Q000201:enzymology*; D010879:Piperazines / Q000494:pharmacology; D011493:Protein Kinase C / Q000037:antagonists & inhibitors; D011994:Recombinant Proteins / Q000494:pharmacology; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D014366:Tryptophan Oxygenase / Q000096:biosynthesis*
D000077190:Interferon alpha-2; D016898:Interferon-alpha; D007546:Isoquinolines; D010879:Piperazines; D011994:Recombinant Proteins; D016899:Interferon-beta; D007371:Interferon-gamma; D019307:1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; D014366:Tryptophan Oxygenase; D011493:Protein Kinase C; D013755:Tetradecanoylphorbol Acetate