title: Angiotropic lymphoma (malignant angioendotheliomatosis) presenting with rapidly progressive dementia.
abstract: An 87-year-old male presented with rapidly progressive dementia, disorder of consciousness and myoclonus, suggesting Creutzfeldt-Jakob disease, but with nonspecific EEG and negative CT findings. Autopsy revealed a malignant angiotropic lymphoma with accumulation of tumor cells within small vessels of the brain and visceral organs. Immunohistochemistry disclosed a large cell lymphoma of B cell type.
authors.affiliation: Pathologisch-bakteriologisches Institut, Psychiatrisches Krankenhaus, Wien, Austria.
authors.forename: M
authors.initials: M
authors.lastname: Drlicek
authors.forename: W
authors.initials: W
authors.lastname: Grisold
authors.forename: U
authors.initials: U
authors.lastname: Liszka
authors.forename: P
authors.initials: P
authors.lastname: Hitzenberger
authors.forename: E
authors.initials: E
authors.lastname: Machacek
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000473:pathology*; D002102:Cadaver; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis; D003704:Dementia / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006390:Hemangioendothelioma / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology; D008297:Male; D014781:Viscera / Q000098:blood supply