title: [Prolonged mechanical nasal ventilation. Apropos of 27 case of myopathy].
abstract: We report the results of a retrospective study of a group of 27 patients with a myopathy who were ventilated at home using a nasal mask over a period of 5 years. Twelve patients were ventilated in a preventive fashion before any orthopaedic surgical intervention and 15 out of necessity because of respiratory failure and/or hypercapnia. There was a statistically significant improvement in the PaO2 while the PaCO2 remained stable. The vital capacity (CV) was unaltered. Side effects were relatively frequent but did not lead to this method of ventilation being stopped. One patient died from a very advanced cardio-myopathy after having stopped his own assisted ventilation. Another patient died at home of bronchial congestion. One patient had a tracheotomy after 3 years of ventilation. The treatment was judged overall as positive amongst the 19 patients who responded to a questionnaire anonymously. We are able to confirm the efficacy of this mode of ventilation by the nasal route as much therapeutically as prophylactically, which is against the recently reported results in a multi-centre study.
authors.affiliation: Service des Explorations Fonctionnelles, CHU, Caen.
authors.forename: J Y
authors.initials: JY
authors.lastname: Rigault
authors.forename: F
authors.initials: F
authors.lastname: Leroy
authors.forename: C
authors.initials: C
authors.lastname: Poncey
authors.forename: J
authors.initials: J
authors.lastname: Brun
authors.forename: J F
authors.initials: JF
authors.lastname: Mallet
mesh_terms: D000293:Adolescent; D000328:Adult; D002245:Carbon Dioxide / Q000097:blood; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008397:Masks; D008875:Middle Aged; D009136:Muscular Dystrophies / Q000628:therapy*; D009666:Nose; D010100:Oxygen / Q000097:blood; D017060:Patient Satisfaction; D011175:Positive-Pressure Respiration / Q000295:instrumentation / Q000379:methods; D011300:Preoperative Care; D012121:Respiration, Artificial / Q000295:instrumentation / Q000379:methods*; D012131:Respiratory Insufficiency / Q000517:prevention & control / Q000628:therapy; D012189:Retrospective Studies; D014797:Vital Capacity
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen
vernacular_title: Ventilation mécanique prolongée par voie nasale. A propos de 27 cas de myopathie.