[What position to take for Kaposi's sarcoma in organ transplantation?].
Kaposi's Sarcoma (KS) is a tumor of multicentric origin, accounting for 4% of the observed neoplasia among organ transplant recipients. Its exact pathogenesis is still unknown. The diagnosis must be suspected in view of skin and/or subcutaneous tumor lesions with potential visceral involvement, which are easily confirmed by histological examination. Initial staging of the disease in 4 subgroups allows to guide therapy and prognosis. Therapeutic options depend on the transplanted organ and on results of early staging at time of diagnosis and treatment may associate: decrease and/or cessation of immunosuppression, laser therapy, radiotherapy and/or chemotherapy.
Farge
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Hôpital Saint-Louis, Pavillon Lugol, Paris.
Frances
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C
D006801:Humans; D007165:Immunosuppression Therapy; D016377:Organ Transplantation / Q000009:adverse effects*; D011379:Prognosis; D012514:Sarcoma, Kaposi / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology / Q000628:therapy
Quelle attitude à adopter devant un sarcome de Kaposi chez le transplanté d'organe? Groupe Collaboratif de recherche de transplantation de l'Ile-de-France (GCIF).