title: [The characteristics of the long-term continuous cultivation of a cell line chronically infected with the human immunodeficiency virus type-1].
abstract: A chronically HIV-1-infected culture of continuous human monocytes producing infectious virus during long-term continuous cultivation (over 200 passages) without the addition of noninfected cells was generated. HIV-1 produced by this culture had typical morphology and complete set of virus-specific proteins. This cell line is proposed for use as an additional model for the evaluation of antiviral effects of various drugs.
authors.forename: O A
authors.initials: OA
authors.lastname: Mamaeva
authors.forename: O A
authors.initials: OA
authors.lastname: Pliasunova
authors.forename: T R
authors.initials: TR
authors.lastname: Proniaeva
authors.forename: A G
authors.initials: AG
authors.lastname: Pokrovskiĭ
authors.forename: V K
authors.initials: VK
authors.lastname: Tkachev
authors.forename: E V
authors.initials: EV
authors.lastname: Karamov
authors.forename: I A
authors.initials: IA
authors.lastname: Rudneva
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000382:microbiology*; D002460:Cell Line; D002478:Cells, Cultured / Q000382:microbiology; D002908:Chronic Disease; D003470:Culture Media; D015488:HIV Antigens / Q000032:analysis; D015497:HIV-1 / Q000276:immunology; D006801:Humans; D009000:Monocytes / Q000382:microbiology; D012692:Serial Passage; D014764:Viral Proteins / Q000032:analysis; D014776:Virus Cultivation / Q000379:methods
chemical_list: D003470:Culture Media; D015488:HIV Antigens; D014764:Viral Proteins
vernacular_title: Osobennosti dlitel'nogo nepreryvnogo kul'tivirovaniia linii kletok, khronicheski infitsirovannoĭ virusom immunodefitsita cheloveka 1 tipa.