Human monocyte antigens in a random sample from Japan.
We studied a random sample of Japanese and compared both Japanese and German monocyte antigen frequencies and performed a segregation analysis in Japanese families. In Japanese, the following gene frequencies were established: 0.1033 for HMA-A1; 0.0299 for HMA-A3; 0.0033 for HMA-A6; 0.1521 for HMA-B2. Data on the gene frequency in Germans were presented by Rose. In this comparison, the frequency for HMA-B2 in Japanese is more than two times higher; for antigen HMA-A6, the Japanese is a fifth of the German quantity. The antigen HMA-B4 was not found in Japanese. The results we obtained from family analysis confirmed an unambiguous autosomal, codominant inheritance of the examined HMA antigens.
Nagai
T
T
Department of Hemogenetics, Kitasato University School of Hygienic Sciences, Sagamihara-shi, Japan.
Sugita
Y
Y
Kurihara
M
M
Ikeda
T
T
Rose
M
M
D005787:Gene Frequency; D005858:Germany; D006801:Humans; D007519:Isoantigens / Q000235:genetics*; D007564:Japan; D009000:Monocytes / Q000276:immunology*
D007519:Isoantigens