[A comparison of the protective properties of preparations of the virion and nonvirion ("soluble") antigens of the tick-borne encephalitis virus].
A comparative assessment of the protective properties of virion (VA) and nonvirion ("soluble") (NA) antigens of tick-borne encephalitis virus prepared as inactivated samples close in their parameters to vaccine preparations was carried out. The NA in the preparations free from VA or containing only trace, nonprotective amounts of it, was shown to have significantly lower protective properties than VA and exerted no booster effect on the protective activity when added to VA preparations.
Liapustin
V N
VN
Pivanova
G P
GP
Karavanov
A S
AS
Lashkevich
V A
VA
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis / Q000276:immunology* / Q000302:isolation & purification; D004353:Drug Evaluation, Preclinical; D004669:Encephalitis Viruses, Tick-Borne / Q000276:immunology* / Q000472:pathogenicity; D004675:Encephalitis, Tick-Borne / Q000517:prevention & control; D007114:Immunization; D051379:Mice; D008807:Mice, Inbred BALB C; D011817:Rabbits; D012995:Solubility; D015164:Vaccines, Inactivated / Q000032:analysis / Q000276:immunology / Q000302:isolation & purification; D014765:Viral Vaccines / Q000032:analysis / Q000276:immunology* / Q000302:isolation & purification; D014771:Virion / Q000737:chemistry / Q000276:immunology* / Q000302:isolation & purification
D000956:Antigens, Viral; D015164:Vaccines, Inactivated; D014765:Viral Vaccines
Sopostavlenie protektivnykh svoĭstv preparatov virionnogo i nevirionnogo ("rastvorimogo") antigenov virusa kleshchevogo éntsefalita.