Skeletal muscle oxygenation monitoring by near infrared spectroscopy.
The oxygenation of human forearm muscle tissue was studied using an optic fiber fast scanning spectrophotometer. We investigated near infrared (700-1100 nm) hemoglobin (Hb) and myoglobin (Mb) spectral changes in flow and/or oxygen-limited conditions. The superimposition of deoxy Hb and deoxy Mb spectra was confirmed "in vivo" on perfluorocarbon-blood exchanged transfused rats. Oxygenation changes were evaluated in 15 volunteers during 10 min forearm arterial occlusion. Rapid desaturation occurred until a plateau was reached after about 4 min, suggesting rapid anaerobic glycolytic activation.
De Blasi
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Istituto di Anestesiologia e Rianimazione, I Università di Roma, Policlinico Umberto I, Italy.
Quaglia
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Ferrari
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D000818:Animals; D005466:Fluorocarbons; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D009132:Muscles / Q000098:blood supply / Q000378:metabolism*; D009211:Myoglobin / Q000378:metabolism*; D010101:Oxygen Consumption; D051381:Rats; D011919:Rats, Inbred Strains; D013055:Spectrophotometry, Infrared
D005466:Fluorocarbons; D006454:Hemoglobins; D009211:Myoglobin