Oncogenes and growth factors in renal cell carcinoma.
Oncogenes and growth factors play a role in normal cellular processes such as growth and differentiation. In addition, considerable circumstantial evidence indicates that these genes may be responsible for the induction and/or maintenance of human malignancies. There are different oncogene families; up to now only a small number has been tested in renal cancer cells.
Peter
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Urologische Klinik und Poliklinik, Heinrich-Heine-Universität Düsseldorf, BRD.
D002292:Carcinoma, Renal Cell / Q000235:genetics*; D004273:DNA, Neoplasm / Q000235:genetics*; D004815:Epidermal Growth Factor / Q000235:genetics; D016762:Genes, fos; D016259:Genes, myc; D011905:Genes, ras; D006801:Humans; D007680:Kidney Neoplasms / Q000235:genetics*; D009857:Oncogenes; D014409:Tumor Necrosis Factor-alpha / Q000235:genetics
D004273:DNA, Neoplasm; D014409:Tumor Necrosis Factor-alpha; D004815:Epidermal Growth Factor