title: Cryptococcal meningitis in pregnancy: a case report.
abstract: We report a pregnant woman with cryptococcal meningitis. She experienced symptoms of meningitis before gestation which worsened during pregnancy. Combined treatment of amphotericin B and flucytosine, including ventriculo-peritoneal shunt gave a favorable outcome for both the patient and her child. We suggest that pregnant women with cryptococcal meningitis should continue their pregnancy and prefer to use combination of both drugs in standard doses because of the effectiveness, shorter duration of treatment and less toxicity than amphotericin B alone.
authors.affiliation: Department of Medicine, Faculty of Medicine, Khon Kaen University, Thailand.
authors.forename: V
authors.initials: V
authors.lastname: Chotmongkol
authors.forename: S
authors.initials: S
authors.lastname: Siricharoensang
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000008:administration & dosage / Q000627:therapeutic use; D002557:Cerebrospinal Fluid Shunts; D003131:Combined Modality Therapy; D005260:Female; D005437:Flucytosine / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D016919:Meningitis, Cryptococcal / Q000175:diagnosis / Q000628:therapy*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000628:therapy*
chemical_list: D000666:Amphotericin B; D005437:Flucytosine