Research note: naloxone inhibits drinking in the chick induced by angiotensin II.
Subcutaneous injection of Angiotensin II (AII) induces a rapid increase in water intake in the chick. These studies were designed to determine whether this response was mediated through the opioid system. Injection of AII stimulated a rapid increase in water intake. Administration of naloxone, an opioid antagonist, attenuated AII-induced drinking in the chick. These data would indicate that the opioids may be involved in the drinking response elicited by AII.
Firman
J D
JD
Department of Animal Sciences, University of Missouri, Columbia 65211.
Volmert
R F
RF
D000804:Angiotensin II / Q000008:administration & dosage / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D000818:Animals; D002645:Chickens / Q000502:physiology*; D004305:Dose-Response Relationship, Drug; D004326:Drinking / Q000187:drug effects*; D007273:Injections, Intramuscular / Q000662:veterinary; D007279:Injections, Subcutaneous / Q000662:veterinary; D008297:Male; D009270:Naloxone / Q000008:administration & dosage / Q000494:pharmacology*; D009271:Naltrexone / Q000008:administration & dosage / Q000494:pharmacology
D000804:Angiotensin II; D009270:Naloxone; D009271:Naltrexone