title: [Seronegative rheumatism of late onset. Incidence and atypical forms of spondylarthropathy].
abstract: The authors reviewed the files of male patients who have been hospitalized over a 12 year period for a rheumatoid-factor negative arthritis beginning after age 50. Polymyalgia rheumatica, psoriasis or crystal-induced arthritis were excluded. The remaining 105 observations were classified according to published criteria in rheumatoid arthritis (RA), reactive arthritis or ankylosing spondylitis (AS). Twenty-nine patients had RA and 29 had AS with equal numbers of axial and peripheral types. Four patients had reactive arthritis, one of them had also AS. Forty-four patients had "unclassified arthritis". Among the latter, 14 were B27 positive, 21 were B27 negative, 9 were not typed. Some features were more frequent in B27+ patients: an assymetrical oligoarthritis of the lower limbs with minimal signs of inflammation at synovial analysis or at synovial biopsy; frequent unilateral edema; marked, constitutional signs; very high ESR. Nine patients, all B27+, met the diagnostic criteria of spondylarthropathy. B27 typing thus appears relevant to the classification of late-onset, seronegative rhumatisms.
authors.affiliation: Service de Rhumatologie, Hôpital Saint-Jacques, Clermont-Ferrand.
authors.forename: J J
authors.initials: JJ
authors.lastname: Dubost
authors.forename: J M
authors.initials: JM
authors.lastname: Ristori
authors.forename: C
authors.initials: C
authors.lastname: Zmantar
authors.forename: B
authors.initials: B
authors.lastname: Sauvezie
mesh_terms: D016918:Arthritis, Reactive / Q000453:epidemiology / Q000276:immunology; D001172:Arthritis, Rheumatoid / Q000453:epidemiology / Q000276:immunology; D015796:HLA-B27 Antigen / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D012216:Rheumatic Diseases / Q000145:classification* / Q000453:epidemiology / Q000276:immunology; D013167:Spondylitis, Ankylosing / Q000453:epidemiology / Q000276:immunology
chemical_list: D015796:HLA-B27 Antigen
vernacular_title: Rhumatismes séronégatifs à début tardif. Fréquence et atypies des spondylarthropathies.