[Treatment of dry eye syndrome with lacrimal gel: a randomized multicenter study].
The appearance on the French market of a carbomer tear substitute, Gel-Larmes, an original galenic form, constitutes a real therapeutic progress in the treatment of dry eye syndrome. An open randomized multicentric trial was conducted comparing the tolerance and efficacy of Gel-Larmes with those of eye drops containing chondroitin sulphate. The statistical analysis evidences an inferior average number of daily instillations for Gel-Larmes, its better efficacy on the symptoms as well as on the objective criteria: biomicroscopic examination, break-up time, rose Bengal test. The tolerance of the product is excellent and 81% of the patients express their wish to pursue Gel-Larmes versus 54% for the reference product.
Laroche
L
L
Hôpital St-Antoine, Paris.
Arrata
M
M
Brasseur
G
G
Lagoutte
F
F
Le Mer
Y
Y
Lumbroso
P
P
Mercante
M
M
Normand
F
F
Rigal
D
D
Roncin
S
S
D000180:Acrylic Resins / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000998:Antiviral Agents / Q000627:therapeutic use*; D015352:Dry Eye Syndromes / Q000188:drug therapy*; D005260:Female; D005782:Gels; D006801:Humans; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions; D013997:Time Factors
D000180:Acrylic Resins; D000998:Antiviral Agents; D005782:Gels; D009883:Ophthalmic Solutions; C006903:carbopol 940
Traitement de la sécheresse oculaire par gel lacrymal: étude multicentrique randomisée.