The structure of 6-phosphogluconate dehydrogenase refined at 2.5 A resolution.
The three-dimensional structure of ovine 6-phosphogluconate dehydrogenase, refined at 2.5 A resolution with a residual for all data of 18.5%, is reported. This model, based on improved diffraction data and a corrected sequence, supersedes that reported earlier. Each subunit of the dimer has three domains: a beta-alpha-beta domain binds NADP; an all alpha domain provides much of the dimer interface; the C-terminal tail burrows into the second subunit.
Adams
M J
MJ
Laboratory of Molecular Biophysics, Oxford University, England.
Gover
S
S
Leaback
R
R
Phillips
C
C
Somers
D O
DO
D015394:Molecular Structure; D010734:Phosphogluconate Dehydrogenase / Q000737:chemistry*; D011487:Protein Conformation; D014961:X-Ray Diffraction
D010734:Phosphogluconate Dehydrogenase