title: [HLA class II DP antigens and bone marrow transplantation].
abstract: The biochemical structure of the HLA class II DP antigens is close to that of the remainder DR and DQ isotypes. Nevertheless, they may play a peculiar functional role. Their importance in bone marrow transplantation, where a complete HLA class II identity between graft donor and recipient is requested, is not yet known. The detection of a DP mismatch by using the mixed lymphocyte reaction is quite difficult. The role of such a mismatch in the incidence of graft versus host disease (GVHD) or graft rejection has to be defined. Studies on large series of recombinant families, using oligotyping, are necessary.
authors.affiliation: Centre de Transfusion sanguine, Strasbourg.
authors.forename: A
authors.initials: A
authors.lastname: Urlacher
authors.forename: J P
authors.initials: JP
authors.lastname: Bergerat
authors.forename: A
authors.initials: A
authors.lastname: Cesbron
authors.forename: J D
authors.initials: JD
authors.lastname: Bignon
authors.forename: M M
authors.initials: MM
authors.lastname: Tongio
mesh_terms: D016026:Bone Marrow Transplantation / Q000276:immunology*; D002478:Cells, Cultured; D006084:Graft Rejection / Q000276:immunology; D006086:Graft vs Host Disease / Q000453:epidemiology / Q000276:immunology; D006682:HLA-DP Antigens / Q000276:immunology*; D006801:Humans; D008214:Lymphocytes / Q000276:immunology
chemical_list: D006682:HLA-DP Antigens
vernacular_title: Antigènes HLA de classe II DP et greffe de moelle osseuse.