title: Local anesthetic mortality: report of case.
abstract: The case of a healthy five-year-old, thirty-six pound female patient scheduled for multiple extractions is reported. The child received a total dose of 270 mg of mepivacaine, instead of the correct dose of 72 mg, which resulted in multiple seizures, hospital admission, pneumonia, and death caused by anoxic brain injury secondary to cardiopulmonary arrest following the overdose.
authors.affiliation: University of Pennsylvania, School of Dental Medicine, Philadelphia 19104-6003.
authors.forename: E V
authors.initials: EV
authors.lastname: Hersh
authors.forename: M L
authors.initials: ML
authors.lastname: Helpin
authors.forename: O B
authors.initials: OB
authors.lastname: Evans
mesh_terms: D000766:Anesthesia, Dental / Q000009:adverse effects*; D000772:Anesthesia, Local / Q000009:adverse effects*; D002675:Child, Preschool; D062787:Drug Overdose; D005260:Female; D006323:Heart Arrest / Q000139:chemically induced; D006801:Humans; D008619:Mepivacaine / Q000506:poisoning*; D012640:Seizures / Q000139:chemically induced
chemical_list: D008619:Mepivacaine