title: Azathioprine for treatment of immune-mediated thrombocytopenia in two horses.
abstract: Azathioprine, a thiopurine antimetabolite used in the treatment of immune-mediated thrombocytopenia in human beings and dogs, was used in 2 cases of immune-mediated thrombocytopenia in horses that failed to respond to corticosteroid therapy alone. Platelet counts were increased to acceptable values in both horses. One horse returned to a successful racing career, and the other was euthanatized after developing renal disease and mild laminitis.
authors.affiliation: Department of Clinical Studies, George D. Widener Hospital, New Balton Center, School of Veterinary Medicine, University of Pennsylvania, Kennett Square 19348.
authors.forename: K A
authors.initials: KA
authors.lastname: Humber
authors.forename: J
authors.initials: J
authors.lastname: Beech
authors.forename: T A
authors.initials: TA
authors.lastname: Cudd
authors.forename: J E
authors.initials: JE
authors.lastname: Palmer
authors.forename: S Y
authors.initials: SY
authors.lastname: Gardner
authors.forename: M M
authors.initials: MM
authors.lastname: Sommer
mesh_terms: D000818:Animals; D001327:Autoimmune Diseases / Q000188:drug therapy / Q000662:veterinary*; D001379:Azathioprine / Q000627:therapeutic use*; D003907:Dexamethasone / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006734:Horse Diseases / Q000188:drug therapy*; D006736:Horses; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D013921:Thrombocytopenia / Q000188:drug therapy / Q000662:veterinary*; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D014750:Vincristine; D003907:Dexamethasone; D001379:Azathioprine; D011241:Prednisone