title: Cocaine in decomposed human remains.
abstract: From March 1988 through March 1990, at the Philadelphia Medical Examiner's Office toxicology laboratory, samples from 77 decomposed human bodies were tested for the presence of cocaine, employing gas chromatography/mass spectrometry (GC-MS). The material analyzed included decomposed soft tissue, bloody decomposition fluid, mummified tissue, maggots, and beetle feces. Twenty-two cases (28.6%) were positive for cocaine, many of these cases in states of advanced decomposition. These findings indicate the usefulness of testing decomposed tissue for cocaine in all cases where its presence is suspected. This is contrary to what might be expected, since cocaine is generally labile and rapidly broken down by both enzymatic and nonenzymatic mechanisms.
authors.affiliation: Medical Examiner's Office, Philadelphia, PA.
authors.forename: D T
authors.initials: DT
authors.lastname: Manhoff
authors.forename: I
authors.initials: I
authors.lastname: Hood
authors.forename: F
authors.initials: F
authors.lastname: Caputo
authors.forename: J
authors.initials: J
authors.lastname: Perry
authors.forename: S
authors.initials: S
authors.lastname: Rosen
authors.forename: H G
authors.initials: HG
authors.lastname: Mirchandani
mesh_terms: D000818:Animals; D003042:Cocaine / Q000032:analysis*; D001517:Coleoptera / Q000737:chemistry; D004175:Diptera / Q000737:chemistry; D005243:Feces / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007814:Larva / Q000737:chemistry; D009132:Muscles / Q000737:chemistry; D011180:Postmortem Changes
chemical_list: D003042:Cocaine