[Physiological status of the body and prediction of the effectiveness of drug therapy of depression. I. Physiological indicators of the reaction to antidepressive drugs].
Evaluation of pulse and breathing rhythm, postural muscle tone, mood and simple reaction time to auditory signal were conducted sevenfold in each of 35 patients with endogenous depression during the six weeks of antidepressant administration. Increased pulse and breath rate and improved mood on the third day of treatment differentiates good and poor responders to the applied treatment. A hypothesis concerning a possible role of observed changes in the balance of autonomous nervous system in the third day of treatment as a positive prognostic sign for the efficiency of medication is evaluated. It appears that mood self-rating on an analogous scale, breath rhythm and postural muscle tone may be used as new early indices of antidepressant drugs efficiency.
Slusarska
M
M
II Kliniki Psychiatrycznej Instytutu Psychiatrii i Neurologii.
Wójcik
M
M
D000328:Adult; D000339:Affect / Q000187:drug effects* / Q000502:physiology; D000368:Aged; D000928:Antidepressive Agents / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000188:drug therapy* / Q000503:physiopathology / Q000523:psychology; D005260:Female; D006339:Heart Rate / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009129:Muscle Tonus / Q000187:drug effects* / Q000502:physiology; D011379:Prognosis; D012074:Remission Induction; D012119:Respiration / Q000187:drug effects* / Q000502:physiology
D000928:Antidepressive Agents
Stan fizjologiczny organizmu a przewidywanie skuteczności farmakoterapii depresji w przebiegu chorób afektywnych. I. Fizjologiczne wskaźniki reakcji na leki przeciwdepresyjne.