[Focal dystonias and facial hemispasm: treatment with botulinum A toxin].
We report the results of the treatment of 80 patients with various idiopathic focal dystonia and essential hemifacial spasm with Botulinum A toxin. A statistically significant improvement was obtained in our 34 patients with blepharospasm, 19 patients with hemifacial spasm, 59% of 22 patients with cervical dystonia and 60% of 5 patients with hand dystonia. Mean duration of the benefit of each injection was 15.3, 16.3, 7.6 and 8.7 weeks respectively. Adverse effects were local and transient. We concluded that botulinum A toxin is a safe and effective therapy for patients with focal dystonia and hemifacial spasm.
Astarloa
R
R
Servicio de Neurología, Fundación Jiménez Díaz, Madrid.
Morales
B
B
Sánchez
V
V
Peñafiel
N
N
Rábano
J
J
Oliván
J
J
García de Yébenes
J
J
D001764:Blepharospasm / Q000188:drug therapy*; D001905:Botulinum Toxins / Q000008:administration & dosage / Q000627:therapeutic use*; D005152:Facial Muscles / Q000187:drug effects; D006801:Humans; D007279:Injections, Subcutaneous; D013035:Spasm / Q000188:drug therapy*; D014103:Torticollis / Q000188:drug therapy*
D001905:Botulinum Toxins
Distonías focales y hemiespasmo facial: tratamiento con toxina botulínica A.