[Study of revaccination with primary hamster kidney cell rabies vaccine in human beings and its possibility of pre-exposure prevention of rabies].
This paper reported that revaccination of antirabies PHKC-RV led to strong increase of antibody after two-dose immunization, vaccinees were reimmunized once with PHKC-vaccine within 7 years (ranging from 6 months to 7 years). Then 7 days later seroconversion was found in 85.71% revaccinees. The antibody level in 7th days of revaccinees was similar to those in 45th days of primary routine five-dose vaccination. In comparison of 7th, 14th, 30th-day level, reimmunization was significantly more effective than routine method (P less than 0.005). In addition, the antibody produced by reimmunization lasted much longer. So it implied that pre-exposure immunization for rabies control has its advantage and feasibility.
Chen
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Anti-epidemic Station of Jining City, Shandong Province.
D000914:Antibodies, Viral / Q000097:blood*; D006801:Humans; D007117:Immunization, Secondary; D011818:Rabies / Q000517:prevention & control*; D011819:Rabies Vaccines; D011820:Rabies virus / Q000276:immunology*; D013997:Time Factors
D000914:Antibodies, Viral; D011819:Rabies Vaccines