[The immediate results of radiation therapy with polyradiomodification of the late stages in cancer of the oral mucosa].
Radiotherapy and polyradiomodification (metronidazole in a dose of 2.5 g/m2 and 30 min hyperthermia) result in regression of the carcinoma of the buccal mucosa and the pharynx in 72% of patients with Stages III-IV condition. No side effects of metronidazole are associated with this dose of the drug. The suggested polyradiomodification somewhat increases the normal mucosal radiosensitivity and permits a course of long-distance gamma-beam therapy in the dynamic fractionation mode.
Vorob'ev
Iu I
IuI
Dzharadat
I
I
D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy*; D003131:Combined Modality Therapy / Q000379:methods; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D009367:Neoplasm Staging; D011879:Radiotherapy Dosage; D012074:Remission Induction
D008795:Metronidazole
Neposredstvennye rezul'taty luchevoĭ terapii s poliradiomodifikatsieĭ pozdnikh stadiĭ raka slizistoĭ obolochki rta.