[Cicatricial, antibacterial and antimycotic effects of tepescohuite in experimental animals].
The cicatricial and antibacterial effects of the sterile powder of the barks of tepescohuite (Mimosa tenuiflora), 2% mupirocin ointment, and 0.9% saline were compared. The experiment was performed in rabbits with chemically induced burns clinically, histopathologically, bacteriologically, and mycologically controlled. No statistically significant difference was found among the three treatment modalities. Due to the potentially hepatotoxic effects and low therapeutic efficacy of tepescohuite it should not be used in human beings.
Palacios
C
C
Departamento de Dermatología, Instituto Nacional de Pediatría, S.S., México, D.F.
Reyes
R E
RE
López-Martínez
R
R
de León
B
B
Pablos
J L
JL
Ruiz-Maldonado
R
R
D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use* / Q000633:toxicity; D000935:Antifungal Agents / Q000627:therapeutic use* / Q000633:toxicity; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification; D002057:Burns, Chemical / Q000188:drug therapy*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology; D003436:Croton Oil / Q000633:toxicity; D003869:Dermabrasion; D004353:Drug Evaluation, Preclinical; D005658:Fungi / Q000187:drug effects / Q000302:isolation & purification; D006212:Hallucinations / Q000139:chemically induced; D016712:Mupirocin / Q000627:therapeutic use; D019800:Phenol; D010636:Phenols / Q000633:toxicity; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use* / Q000633:toxicity; D010946:Plants, Medicinal; D011817:Rabbits; D012867:Skin / Q000382:microbiology; D012874:Skin Diseases, Infectious / Q000517:prevention & control; D014197:Trees; D014945:Wound Healing / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D010636:Phenols; D010936:Plant Extracts; C075006:tepescohuite; D019800:Phenol; D003436:Croton Oil; D016712:Mupirocin
Efectos cicatrizante, antibacteriano y antimicótico del tepescohuite en animales de experimentación.