title: Incidence of symptomatic mild hypoglycaemic events: a prospective study in adult patients with insulin-treated diabetes mellitus using a portable microcomputer-based data-logger.
abstract: A new method for recording mild symptomatic hypoglycaemic events was evaluated. A pilot study was conducted using a portable microcomputer-based data-logger which was carried for 10 days by 38 adult patients with insulin-treated diabetes mellitus. The patients recorded symptomatic hypoglycaemic events, meals and sleeping-hours. The recording was prospective and continuous and did not allow any corrections afterwards. No patients had any problems in carrying or handling the data-logger and compliance was good. A total of 76 hypoglycaemic events were recorded in 29 patients. Two patients had hypoglycaemic events that they were unable to manage without help from another person. There was a peak in the incidence of hypoglycaemic events late postprandially, particularly in patients treated with a four-dose insulin regime with fast-acting insulin before meals. A portable microcomputer-based data-logger is a reliable new method for recording symptomatic mild hypoglycaemic events. The incidence of mild hypoglycaemic events was higher than previously reported.
authors.affiliation: Department of Internal Medicine, Central County Hospital, Sweden.
authors.forename: E
authors.initials: E
authors.lastname: Schvarcz
authors.forename: M
authors.initials: M
authors.lastname: Palmér
authors.forename: C
authors.initials: C
authors.lastname: Berne
authors.forename: E
authors.initials: E
authors.lastname: Björk
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D015190:Blood Glucose Self-Monitoring; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy*; D004334:Drug Administration Schedule; D004435:Eating; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007003:Hypoglycemia / Q000139:chemically induced* / Q000453:epidemiology; D015994:Incidence; D007328:Insulin / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D008838:Microcomputers; D008875:Middle Aged; D011446:Prospective Studies
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007328:Insulin