[Tumors of the upper urothelium and cyclophosphamide: presentation of a case and review of the literature].
We report a case of upper urothelial tumor in a patient who had previously received prolonged cyclophosphamide therapy for Waldeström's macroglobulinemia. Although bladder tumors in cyclophosphamide-treated patients are relatively frequent, upper urothelial tumors are rare. Only 5 cases of this latter tumor type have been reported as of 1987. The literature on this disease entity is reviewed. Patients who have received prolonged therapy with cyclophosphamide or similar drugs must be followed very closely.
de Castro Barbosa
F
F
Departamento de Urología, Facultad de Medicina, Universidad de Navarra, Pamplona, España.
Rosell Costa
D
D
Agüera Fernández
L
L
Isa Kroon
W A
WA
Sánchez de la Muela
P
P
Robles García
J E
JE
Zudaire Bergera
J J
JJ
Berián Polo
J M
JM
D001500:BCG Vaccine / Q000627:therapeutic use; D002295:Carcinoma, Transitional Cell / Q000139:chemically induced* / Q000628:therapy; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000009:adverse effects* / Q000627:therapeutic use; D004317:Doxorubicin / Q000627:therapeutic use; D006801:Humans; D007680:Kidney Neoplasms / Q000139:chemically induced* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009378:Neoplasms, Multiple Primary / Q000139:chemically induced / Q000628:therapy; D009392:Nephrectomy; D001749:Urinary Bladder Neoplasms / Q000139:chemically induced* / Q000628:therapy; D008258:Waldenstrom Macroglobulinemia / Q000150:complications / Q000188:drug therapy*
D001500:BCG Vaccine; D004317:Doxorubicin; D003520:Cyclophosphamide
Tumores de urotelio superior y ciclofosfamida: presentación de un caso y revisión de la literatura.