[Postradiation regeneration of hemopoiesis with preliminary whole body hyperthermia in mice].
The stimulatory effect of the preliminary whole body hyperthermia (WBH) on postradiation recovery of number both early hemopoietic progenitor cells (CFU-S and CFU-GM) and morphologically identifiable neutrophilic and erythroid cells in bone marrow was demonstrated in mice. Animals were exposed to the WBH (40 degrees C for 1 h.) 20 h before the irradiation in dose 6 Gr. WBH increased surviving of irradiated (7,5 Gr) mice up to 58% (100% lethality in control).
Moroz
B B
BB
Deshevoĭ
Iu B
IuB
Lebedev
V G
VG
Mareĭ
V A
VA
D000818:Animals; D006410:Hematopoiesis / Q000502:physiology* / Q000528:radiation effects; D006979:Hyperthermia, Induced; D008297:Male; D051379:Mice; D011833:Radiation Injuries, Experimental / Q000517:prevention & control*; D012038:Regeneration / Q000502:physiology*; D013997:Time Factors
Postradiatsionnaia regeneratsiia gemopoéza v usloviiakh predvaritel'nogo vozdeĭstviia na organizm mysheĭ obshcheĭ gipertermii.