Experimental borderline lepromatous leprosy with intraneural erythema nodosum leprosum in a mangabey monkey (Cercocebus atys).
A sooty mangabey monkey (Cercocebus atys) was inoculated with Mycobacterium leprae and developed borderline lepromatous leprosy and intraneural erythema nodosum leprosum. Previously studied mangabeys have developed only disseminated lepromatous leprosy without reactions. This case broadens the spectrum of leprosy seen in experimentally inoculated animals and further characterizes the nonhuman primate model of leprosy.
Baskin
G B
GB
Tulane Regional Primate Research Center, Tulane University, Covington, Louisiana 70433.
Gormus
B J
BJ
Xu
K
K
Martin
L N
LN
Wolf
R H
RH
Cantrell
C
C
Pezeshkpour
G H
GH
Walsh
G P
GP
Malaty
R
R
Meyers
W M
WM
D000818:Animals; D016665:Cercocebus atys; D004195:Disease Models, Animal; D004893:Erythema Nodosum / Q000473:pathology*; D005260:Female; D015439:Leprosy, Borderline / Q000473:pathology*; D015440:Leprosy, Lepromatous / Q000473:pathology*; D008475:Median Nerve / Q000473:pathology; D010543:Peroneal Nerve / Q000473:pathology; D011826:Radial Nerve / Q000473:pathology; D013979:Tibial Nerve / Q000473:pathology; D014459:Ulnar Nerve / Q000473:pathology