[Comparative studies of toothpastes and toothpaste ingredients in biological systems. 2. Study of toothpaste ingredients and their effects on cell growth].
The influence on cell growth by different ingredients of toothpastes was examined in cell culture. Following parameters were evaluated: protein concentration, MTT-test and cell morphology. Substantial inhibition of cell growth was caused by tensides. Preparations with Tego-Betain had a significantly less influence on cell growth than Texapon. Other ingredients as medical soap, fluoride and preservative showed a very low effect.
Gerckens
B
B
Abt. Parodontologie, Universität Gottingen.
Eisinger
G
G
Krüger
W
W
D000818:Animals; D001622:Betaine / Q000031:analogs & derivatives* / Q000633:toxicity; D002455:Cell Division / Q000187:drug effects*; D002478:Cells, Cultured; D005347:Fibroblasts / Q000187:drug effects; D005460:Fluorides, Topical; D006131:Growth Inhibitors; D051379:Mice; D012967:Sodium Dodecyl Sulfate / Q000633:toxicity*; D013501:Surface-Active Agents / Q000633:toxicity*; D014100:Toothpastes / Q000633:toxicity*
D005460:Fluorides, Topical; D006131:Growth Inhibitors; D013501:Surface-Active Agents; D014100:Toothpastes; C075204:Texapon; D012967:Sodium Dodecyl Sulfate; D001622:Betaine; C065099:Tego-Betain
Vergleichende Untersuchungen von Zahnpasten und Zahnpasten-Bestandteilen in biologischen Systemen: 2. Untersuchungen von Zahnpasten-Bestandteilen auf ihre zellwachstumsbeeinflussende Wirkung.