Zinc protection against lipid peroxidation from cadmium.
Effect of zinc and cadmium on lipid peroxidation and catalase activity in liver, heart, brain and testis was determined in order to characterise the interaction of zinc with cadmium. Zinc and cadmium both increased lipid peroxidation significantly in the tissues studied. In animals pretreated with zinc prior to cadmium administration, significant decrease in lipid peroxidation in liver was observed. Lipid peroxidation was not affected significantly in testis but a significant increase was observed in heart and brain tissues. Catalase activity in testis increased significantly by zinc treatment with or without cadmium administration.
Khan
S
S
School of Biochemistry, D.A. University, Indore, India.
Khan
M A
MA
Bhatnagar
D
D
Yadav
P
P
Sarkar
S
S
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000201:enzymology; D002104:Cadmium / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D002374:Catalase / Q000187:drug effects / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects*; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D008297:Male; D051379:Mice; D013737:Testis / Q000187:drug effects / Q000201:enzymology; D015032:Zinc / Q000494:pharmacology*
D002104:Cadmium; D002374:Catalase; D015032:Zinc