[Effect of intraventricular injection of anti-beta-endorphin serum on shock after burn in rats].
Intraventricular injections of anti-beta-endorphin serum (8 microliters) at 0, 1, 2, 3 h after burn shock (20% body surface area, 100 degrees C, 20 s) in different group rats prolonged the survival time, delayed the decrease of mean arterial pressure (MAP) and heart rate, and postponed the abnormal changes of ECG. The effect was most prominent at 1 h and little at 3 h after burn.
Hong
X R
XR
Department of Neurobiology, Second Military Medical College, Shanghai, China.
Wang
C H
CH
Lin
B C
BC
Song
C Y
CY
Zhu
H N
HN
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002056:Burns / Q000150:complications; D004562:Electrocardiography / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D007106:Immune Sera / Q000008:administration & dosage*; D007276:Injections, Intraventricular; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012774:Shock, Traumatic / Q000209:etiology / Q000503:physiopathology*; D013997:Time Factors; D001615:beta-Endorphin / Q000276:immunology* / Q000494:pharmacology
D007106:Immune Sera; D001615:beta-Endorphin