title: Effects of some lipophilic carboxylic acid on release of interferon gamma from the human peripheral blood leukocytes.
abstract: Lipophilic carboxylic acids and their salts were tested for the ability of interferon induction in the cultures of human peripheral blood leukocytes. Of 13 tested organic compounds, two were selected: decyl-malonic acid and sodium salt of octylmethane-tri-(2-oxabutanoic)acid--which stimulated the synthesis of low amounts of gamma interferon.
authors.affiliation: Laboratory of Virology, Polish Academy of Sciences, Wrocław.
authors.forename: J
authors.initials: J
authors.lastname: Zielińska-Jenczylik
authors.forename: A D
authors.initials: AD
authors.lastname: Inglot
authors.forename: E
authors.initials: E
authors.lastname: Piasecki
authors.forename: A
authors.initials: A
authors.lastname: Sypuła
authors.forename: M
authors.initials: M
authors.lastname: Albin
authors.forename: J
authors.initials: J
authors.lastname: Młochowski
authors.forename: J
authors.initials: J
authors.lastname: Skarzewski
mesh_terms: D002264:Carboxylic Acids / Q000737:chemistry / Q000494:pharmacology*; D004987:Ethers / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D007369:Interferon Inducers / Q000494:pharmacology; D007371:Interferon-gamma / Q000378:metabolism*; D007962:Leukocytes / Q000187:drug effects* / Q000276:immunology; D008314:Malonates / Q000494:pharmacology; D013329:Structure-Activity Relationship; D014233:Tricarboxylic Acids / Q000494:pharmacology
chemical_list: D002264:Carboxylic Acids; D004987:Ethers; D007369:Interferon Inducers; D008314:Malonates; D014233:Tricarboxylic Acids; C073782:octylmethane-tri-(2-oxabutanoic acid); C073783:decylmalonic acid; D007371:Interferon-gamma