title: Substrate analogue renin inhibitors containing replacements of histidine in P2 or isosteres of the amide bond between P3 and P2 sites.
authors.affiliation: E. Merck Pharmaforschung, Darmstadt, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Raddatz
authors.forename: A
authors.initials: A
authors.lastname: Jonczyk
authors.forename: C J
authors.initials: CJ
authors.lastname: Schmitges
authors.forename: J
authors.initials: J
authors.lastname: Sombroek
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002918:Chymotrypsin / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009842:Oligopeptides / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D013379:Substrate Specificity; D000092502:Renin Inhibitors
chemical_list: D002918:Chymotrypsin; D009842:Oligopeptides; D000092502:Renin Inhibitors