title: Contributing co-variables in clinical trials.
abstract: To accurately compare Class V dentinal bonding studies, it is essential to critically classify the effects of the intraoral location and age of the patient on the retention of resin composite restorations. A mathematical formula for normalization combined with the Weibull analysis also is proposed that could provide CL50 values for the clinical longevity of adhesive restorations.
authors.affiliation: Department of Operative Dentistry, School of Dentistry, University of North Carolina, Chapel Hill 27599-7450.
authors.forename: S C
authors.initials: SC
authors.lastname: Bayne
authors.forename: H O
authors.initials: HO
authors.lastname: Heymann
authors.forename: J R
authors.initials: JR
authors.lastname: Sturdevant
authors.forename: A D
authors.initials: AD
authors.lastname: Wilder
authors.forename: T B
authors.initials: TB
authors.lastname: Sluder
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000571:American Dental Association; D002986:Clinical Trials as Topic / Q000592:standards*; D015986:Confounding Factors, Epidemiologic; D001840:Dental Bonding; D003738:Dental Cements; D003804:Dentin; D006801:Humans; D016015:Logistic Models; D008422:Materials Testing / Q000592:standards*; D008875:Middle Aged; D016019:Survival Analysis; D014481:United States
chemical_list: D003738:Dental Cements