title: Effect of amine fluoride subgingival irrigation on periodontally diseased sites.
abstract: Amine fluoride gel, a surfactant and bactericidal compound was tested for irrigation of periodontal sites in inflammatory periodontal disease. Eight volunteer-patients who had at least 4 sites with probing depths of 6 mm or more in two different quadrants participated in the study. The start of the study was preceded by supragingival scaling. At the selected sites clinical (PI, GI, BOP, probing attachment) and microbial examinations (percentage motile rods and spirochetes) were performed at baseline, 30, 60 and 9 days. Irrigation with AmF gel and saline was performed at experimental and control sites twice weekly during one month. The mean Plaque Index, bleeding on probing and percentage mobile rods and spirochetes, at baseline, were not significantly different between the experimental and control groups, where as the mean gingival index and probing attachment were significantly different. There were decreases in the Plaque and Gingival Indexes, bleeding on probing, percentage motile rods and spirochetes and gain in probing attachment in both experimental and control groups during the test period of 60 days. However, these improvements from baseline values to the periods of 30, 60 and 90 days between the treatment and control groups were not significant. Although mean improvements of the parameters examined were greater in the experimental group, this was probably due to higher baseline values in this group.
authors.affiliation: Department of Periodontology, Faculty of Dental Medicine, Jerusalem.
authors.forename: L
authors.initials: L
authors.lastname: Shapira
authors.forename: S
authors.initials: S
authors.lastname: Kaplan
authors.forename: J
authors.initials: J
authors.lastname: Goultschin
authors.forename: I
authors.initials: I
authors.lastname: Gedalia
mesh_terms: D000328:Adult; D000605:Amino Alcohols / Q000008:administration & dosage*; D001419:Bacteria / Q000187:drug effects; D003774:Dental Plaque Index; D003802:Dentifrices / Q000627:therapeutic use*; D005459:Fluorides / Q000008:administration & dosage*; D005782:Gels; D006801:Humans; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010512:Periodontal Index; D010518:Periodontitis / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000605:Amino Alcohols; D003802:Dentifrices; D005782:Gels; C036238:amine fluoride 297; D005459:Fluorides