Automated microdensitometric quantification of bone ingrowth into porous implants.
The aim of this study was to develop a technique of automated histometric quantification of bone ingrowth into porous implant bodies that minimizes errors of volume determination arising from the section thickness of histologic specimens. A theoretical and experimental deduction is provided for the calculation of implant and bone layer thicknesses from the grey levels of microradiographs made from thick-section specimens. The presented method allows rapid raising of large amounts of histometric data when a computer-aided video system is available. A histologic preparation of specimens that permits the spatial reconstruction of the examined implant volume and analysis of three-dimensional distribution of bone ingrowth is suggested.
Schliephake
H
H
Department of Oral and Maxillofacial Surgery, University Medical School, Hannover, Germany.
Klosa
D
D
Neukam
F W
FW
D015502:Absorptiometry, Photon / Q000379:methods*; D016301:Alveolar Bone Loss / Q000000981:diagnostic imaging*; D000818:Animals; D001861:Bone Regeneration; D015921:Dental Implants; D006882:Hydroxyapatites; D016348:Osseointegration; D011857:Radiographic Image Interpretation, Computer-Assisted; D013552:Swine; D013556:Swine, Miniature
D015921:Dental Implants; D006882:Hydroxyapatites