[The use of sublingual nifedipine in pediatric hypertensive patients at the Hospital de la Capital].
The response to sublingual nifedipina was observed in 7 pediatric patients with renal disease and acute severe hypertension. Average dose used was 0.21 mg/kg, and an initial rapid response was evidenced as early as 3 minutes post administration. The greatest hypotensive effect was seen during the first 30 minutes, but continued its effect up to 60-120 minutes. The drug was well tolerated, of rapid action and results suggests it is efficient in the management of children and adolescents with acute secondary hypertension. No mayor adverse effects were encountered.
Marrero Arroyo
D
D
Departamento de Pediatría, Hospital de la Capital.
Carrer
M T
MT
Molina
M
M
Gómez
M
M
Jiménez
E
E
D000286:Administration, Sublingual; D000293:Adolescent; D002214:Capsules; D002648:Child; D004341:Drug Evaluation; D006769:Hospitals, General; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000378:metabolism; D007231:Infant, Newborn; D009543:Nifedipine / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics; D011647:Puerto Rico; D013997:Time Factors
D002214:Capsules; D009543:Nifedipine
El uso de nifedipina sublingual en pacientes pediátricos hipertensos del Hospital de la Capital.