title: [The use of sublingual nifedipine in pediatric hypertensive patients at the Hospital de la Capital].
abstract: The response to sublingual nifedipina was observed in 7 pediatric patients with renal disease and acute severe hypertension. Average dose used was 0.21 mg/kg, and an initial rapid response was evidenced as early as 3 minutes post administration. The greatest hypotensive effect was seen during the first 30 minutes, but continued its effect up to 60-120 minutes. The drug was well tolerated, of rapid action and results suggests it is efficient in the management of children and adolescents with acute secondary hypertension. No mayor adverse effects were encountered.
authors.affiliation: Departamento de Pediatría, Hospital de la Capital.
authors.forename: D
authors.initials: D
authors.lastname: Marrero Arroyo
authors.forename: M T
authors.initials: MT
authors.lastname: Carrer
authors.forename: M
authors.initials: M
authors.lastname: Molina
authors.forename: M
authors.initials: M
authors.lastname: Gómez
authors.forename: E
authors.initials: E
authors.lastname: Jiménez
mesh_terms: D000286:Administration, Sublingual; D000293:Adolescent; D002214:Capsules; D002648:Child; D004341:Drug Evaluation; D006769:Hospitals, General; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000378:metabolism; D007231:Infant, Newborn; D009543:Nifedipine / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics; D011647:Puerto Rico; D013997:Time Factors
chemical_list: D002214:Capsules; D009543:Nifedipine
vernacular_title: El uso de nifedipina sublingual en pacientes pediátricos hipertensos del Hospital de la Capital.