title: [Synthesis and properties of DNA-duplexes, containing 9-(1'-hydroxy-2'-(hydroxymethyl)ethoxy)methylguanine].
abstract: Phosphoramidite derivative of 9-[1'-hydroxy-2'-(hydroxymethyl)ethoxy]methylguanine (glG) is synthesized which allows one to introduce point modifications in any position of the chemically prepared oligonucleotide chain. Oligonucleotides with 5'-terminal glG can be used in chemical ligation promoted by cyanogen bromide. The modified oligonucleotide duplexes were characterized by melting curves and CD spectra.
authors.forename: E A
authors.initials: EA
authors.lastname: Romanova
authors.forename: L G
authors.initials: LG
authors.lastname: Kuznetsova
authors.forename: E A
authors.initials: EA
authors.lastname: Kubareva
authors.forename: A V
authors.initials: AV
authors.lastname: Tsytovich
authors.forename: I N
authors.initials: IN
authors.lastname: Merenkova
authors.forename: T S
authors.initials: TS
authors.lastname: Oretskaia
authors.forename: E S
authors.initials: ES
authors.lastname: Gromova
authors.forename: Z A
authors.initials: ZA
authors.lastname: Shabarova
mesh_terms: D001483:Base Sequence; D002851:Chromatography, High Pressure Liquid; D002942:Circular Dichroism; D004247:DNA / Q000737:chemistry*; D008969:Molecular Sequence Data; D009692:Nucleic Acid Heteroduplexes / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D009692:Nucleic Acid Heteroduplexes; D004247:DNA
vernacular_title: Sintez i svoĭstva DNK-dupleksov, soderzhashchikh 9-(1'-gidroksi-2'-(gidroksimetil)étoksi)metilguanin.