[The effect of phosphoenolpyruvate on the course of the acute period in experimental myocardial infarct].
It was found in the experiments on dogs, that phosphoenolpyruvate decreased the level of regional metabolic acidosis, stabilized energy metabolism, cardiohemodynamics and enhanced the blood supply of the ischemic myocardium. Anti-ischemic effect of the phosphoenolpyruvate was more significant in comparison with fructose-1,6-diphosphate in isomolar doses.
Sernov
L N
LN
Gatsura
V V
VV
D000818:Animals; D003326:Coronary Circulation / Q000187:drug effects; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D004734:Energy Metabolism / Q000187:drug effects; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D008297:Male; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000503:physiopathology; D009206:Myocardium / Q000378:metabolism; D010728:Phosphoenolpyruvate / Q000627:therapeutic use*; D051381:Rats; D013997:Time Factors
D010728:Phosphoenolpyruvate
Vliianie fosfoenolpiruvata na techenie ostrogo perioda éksperimental'nogo infarkta miokarda.