Constituents of seed of Malva verticillata. VII. Structural features and reticuloendothelial system-potentiating activity of MVS-I, the major neutral polysaccharide.
The structural features of MVS-I, the major neutral polysaccharide isolated from the seeds of Malva verticillata L., were elucidated by controlled Smith degradation, methylation analysis, partial acid hydrolysis and enzymic degradation studies. It has a backbone chain composed of beta-1,3-linked D-glucose and D-galactose residues having branches composed of alpha-1,5-linked L-arabinosyl beta-1,4-linked D-galactose and of beta-1,4-linked D-galactosyl beta-1,3-linked D-glucose residues at position 6 of a part of D-galactose units as side chains. MVS-I showed remarkable reticuloendothelial system-potentiating activity in a carbon clearance test.
Shimizu
N
N
Kyoritsu College of Pharmacy, Tokyo, Japan.
Asahara
H
H
Tomoda
M
M
Gonda
R
R
Ohara
N
N
D002240:Carbohydrate Sequence; D006868:Hydrolysis; D008745:Methylation; D008969:Molecular Sequence Data; D012157:Mononuclear Phagocyte System / Q000187:drug effects*; D011134:Polysaccharides / Q000378:metabolism / Q000494:pharmacology*; D012639:Seeds / Q000378:metabolism*
D011134:Polysaccharides