[Regenerative response of hepatocytes implanted in the spleen].
Regenerative activity of syngenic hepatocytes inoculated into the spleen has been assessed. Partial hepatectomy and cyclosporine were used as regenerative stimuli. Nuclear DNA has been quantified by means of a cytophotometric method, and the intensity of the response has been defined as the Mean Percentage of Regenerating Hepatocytes (MPRH). Both hepatectomy and cyclosporine (alone or associated) have significantly increased splenic MPRH.
García-Alonso
I
I
Hospital de Basurto, Departamento de Cirugía, Universidad del País Vasco.
Barceló
P
P
Portugal
V
V
Bilbao
J
J
de Tejada
I L
IL
Méndez
J
J
D000818:Animals; D016572:Cyclosporine / Q000494:pharmacology; D004247:DNA / Q000032:analysis; D005260:Female; D006498:Hepatectomy; D008099:Liver / Q000166:cytology* / Q000187:drug effects; D008115:Liver Regeneration / Q000187:drug effects; D016031:Liver Transplantation; D051381:Rats; D011916:Rats, Inbred F344 / Q000276:immunology; D013154:Spleen; D013268:Stimulation, Chemical; D016042:Transplantation, Heterotopic
D016572:Cyclosporine; D004247:DNA
Estudio de la respuesta regenerativa de hepatocitos implantados en el bazo.