title: Thrombolytic therapy soon after left heart catheterization--is it safe?
abstract: Puncture of a femoral artery for left heart catheterization is considered a relative contraindication for thrombolytic therapy for some days. We treated 9 patients with systemic thrombolysis who had undergone left heart catheterization in the previous hours. Four patients developed a large hematoma, but only 1 required transfusion. We suggest that thrombolytic therapy can be administered soon after left heart catheterization by the femoral approach, provided that continuous care can be taken over the puncture site.
authors.affiliation: Unidad Coronaria, Hospital Universitario Virgen Macarena.
authors.forename: J C
authors.initials: JC
authors.lastname: García-Rubira
authors.forename: V
authors.initials: V
authors.lastname: López
authors.forename: J
authors.initials: J
authors.lastname: Rojas
authors.forename: J T
authors.initials: JT
authors.lastname: García-Martínez
authors.forename: J M
authors.initials: JM
authors.lastname: Cruz
mesh_terms: D000328:Adult; D006328:Cardiac Catheterization; D005260:Female; D006406:Hematoma / Q000139:chemically induced*; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D013300:Streptokinase / Q000009:adverse effects*; D013997:Time Factors; D010959:Tissue Plasminogen Activator / Q000009:adverse effects*; D014568:Urokinase-Type Plasminogen Activator / Q000009:adverse effects*
chemical_list: D013300:Streptokinase; D010959:Tissue Plasminogen Activator; D014568:Urokinase-Type Plasminogen Activator