Unimolecular decomposition of M+. and [M+H]+ species of some fluorosubstituted acyclic nucleoside analogs.
Electron ionization and fast-atom bombardment mass spectrometry are shown to provide a valid analytical tool for the structural characterization of the title compounds. In fact, diagnostic fragmentation pathways were observed depending on the presence of different substituents (benzyloxy, (benzyloxy, p-tolylthio, p-tolylsulphinyl) as well as of different bases. Regioisomeric compounds could be differentiated by kinetic energy release measurements.
Favretto
D
D
CNR, Padova, Italy.
Traldi
P
P
Bravo
P
P
Viani
F
F
D013058:Mass Spectrometry / Q000379:methods; D009705:Nucleosides / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment
D009705:Nucleosides