title: L-alanine transport by systems A and ASC in plasma membrane vesicles isolated from Ehrlich cells.
abstract: Plasma membrane vesicles were prepared from Ehrlich cells using two-phase system compartmentation. These vesicles accumulated L-alanine mainly by means of Na(+)-dependent transport systems A and ASC. The kinetic of both transport systems could be elucidated by specific inhibition of system A with methyl-aminoisobutyric acid.
authors.affiliation: Laboratorio de Bioquímica, Facultad de Ciencias, Universidad de Málaga, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Luque
authors.forename: J
authors.initials: J
authors.lastname: Márquez
authors.forename: I
authors.initials: I
authors.lastname: Núñez de Castro
authors.forename: M A
authors.initials: MA
authors.lastname: Medina
mesh_terms: D000409:Alanine / Q000378:metabolism*; D026905:Amino Acid Transport Systems; D026921:Amino Acid Transport Systems, Neutral; D000621:Aminoisobutyric Acids / Q000494:pharmacology; D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000378:metabolism*; D002352:Carrier Proteins / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism*; D007700:Kinetics; D051379:Mice; D009363:Neoplasm Proteins / Q000378:metabolism; D027981:Symporters; D014407:Tumor Cells, Cultured / Q000187:drug effects / Q000378:metabolism
chemical_list: D026905:Amino Acid Transport Systems; D026921:Amino Acid Transport Systems, Neutral; D000621:Aminoisobutyric Acids; D002352:Carrier Proteins; D009363:Neoplasm Proteins; D027981:Symporters; C052168:sodium-alanine cotransporter; C017911:2-(methylamino)isobutyric acid; D000409:Alanine