[Mononuclear magnesium in elderly hypertensive patients treated with thiazide].
OBJECTIVE
To study mononuclear magnesium and serum cations (Na, K and Mg) in elderly hypertensive patients treated with hydrochlorothiazide during 90 days.


METHODS
15 elderly hypertensive patients treated with hydrochlorothiazide, 25 mg/day or placebo. A method of freezing produced total lysis of the cells; Mg was measured by atomic spectrophotometry.


RESULTS
No differences were noted in mononuclear or serum magnesium in the thiazide or placebo treated patients, and the diuretic produced significant decreases in supine systolic and diastolic blood pressure.


CONCLUSIONS
Magnesium supplementation does not seem essential in most patients in this conditions.
Faintuch
J J
JJ
Instituto do Coração, Hospital das Clínicas, FMUSP.
Azul
J B
JB
Wajngarten
M
M
Rocha
A dos S
Ados S
D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000627:therapeutic use*; D006973:Hypertension / Q000097:blood / Q000188:drug therapy*; D007963:Leukocytes, Mononuclear / Q000737:chemistry*; D008274:Magnesium / Q000097:blood*; D008297:Male; D011188:Potassium / Q000097:blood; D012964:Sodium / Q000097:blood; D013054:Spectrophotometry, Atomic; D014527:Uric Acid / Q000097:blood; D014882:Water-Electrolyte Balance / Q000187:drug effects
D006852:Hydrochlorothiazide; D014527:Uric Acid; D012964:Sodium; D008274:Magnesium; D011188:Potassium
Magnésio mononuclear em hipertensos idosos tratados com tiazídico.