title: Nitrogranulogen-dependent inhibition of antibody synthesis. II. In vivo studies in mice.
abstract: NTG in higher doses inhibits specific antibody responses in mice when given after but not prior to antigen. The drug also causes suppression of polyclonal humoral responses but to a lesser extent than other alkylating agents.
authors.affiliation: Department of Immunology, Medical School, Warszawa.
authors.forename: Z
authors.initials: Z
authors.lastname: Lagodziński
authors.forename: A
authors.initials: A
authors.lastname: Górski
mesh_terms: D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D000941:Antigens / Q000008:administration & dosage; D001402:B-Lymphocytes / Q000187:drug effects / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology; D007166:Immunosuppressive Agents / Q000494:pharmacology; D008466:Mechlorethamine / Q000008:administration & dosage / Q000494:pharmacology*; D051379:Mice; D008807:Mice, Inbred BALB C; D012756:Sheep; D013154:Spleen / Q000166:cytology / Q000187:drug effects / Q000276:immunology
chemical_list: D000941:Antigens; D007166:Immunosuppressive Agents; D008466:Mechlorethamine