[EEG value for the prediction of the evolution of Alzheimer's type dementia].
Twenty patients selected as probable dementia of the Alzheimer type (DAT) have been examined two times during a mean follow-up period of 14.5 months. Two groups have been distinguished at the end of this period: a cognitively impaired one and a stable one. EEG features at T1, at T2 or the difference T1-T2 does not allow an accurate and predictive discrimination between the two groups. But we cannot conclude that EEG is useless for prediction of the rate of progression of the disease in DAT because most of the cognitively stable patients are also stable for mean frequency. So mean frequency could be an interesting marker of evolutivity but this to be tested with more patients including more subjects reaching the severe stage of dementia.
Gueguen
B
B
Service de neurophysiologie clinique, hôpital Sainte-Anne, Paris, France.
Derouesné
C
C
Bourdel
M C
MC
Guillou
S
S
Rahal
A
A
Landre
E
E
Gasnault
J
J
Ancri
D
D
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000503:physiopathology*; D001921:Brain / Q000503:physiopathology*; D004569:Electroencephalography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged
Intérêt de l'EEG pour la prédiction de l'évolution des démences de type Alzheimer.