Anti-toxoplasma serotitres in ocular toxoplasmosis.
Serological studies are one of the important diagnostic tools used in the investigation of uveitis. This study was based on anti-toxoplasma serotitres obtained from 80 normal healthy adults and 122 patients investigated for ocular toxoplasmosis over a 42 month period. Fifteen per cent of normal healthy sera were found to have low titres (1:64 to 1:256), while 3.8% had high titres (1:1024 or higher). Thirty five eyes of 29 patients had presumed ocular toxoplasmosis based on clinical features and a typical fundal appearance. 89.6% of clinically positive ocular toxoplasmosis were found to have titres ranging from 1:64 to 1:4096. Among the suspected ocular toxoplasmosis cases with a serotitre more than or equal to 1:256, at least 77% had clinical ocular toxoplasmosis.
Phaik
C S
CS
Singapore National Eye Centre.
Seah
S
S
Guan
O S
OS
Chandra
M T
MT
Hui
S E
SE
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis*; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008297:Male; D008875:Middle Aged; D012846:Singapore; D014122:Toxoplasma / Q000276:immunology*; D014126:Toxoplasmosis, Ocular / Q000175:diagnosis* / Q000276:immunology; D014605:Uveitis / Q000469:parasitology
D000913:Antibodies, Protozoan