Chlamydia trachomatis in pelvic inflammatory disease.
C. trachomatis seems to be an important causative organism of pelvic inflammatory disease (PID) as C. trachomatis antigen and/or antibody was found in 234 (69.85%) of 335 patients clinically diagnosed to have PID. Antigen was detected in the lower genital tract of 118 (35.22%) patients whereas IgG antibody was present in 188 (56.11%), of whom 89 (47.34%) had a high titre. Repeat testing of sera of 37 patients showed a rise in antibody titre in 18 (40%). As the success rate of therapy for PID with doxycycline was found to be 80 per cent, early diagnosis and treatment may be recommended to prevent further complications of PID.
Bhujwala
R A
RA
Department of Microbiology, All India Institute of Medical Sciences, New Delhi.
Bhargava
V L
VL
Amatya
S
S
Sengupta
S
S
D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood*; D000942:Antigens, Bacterial / Q000032:analysis*; D002690:Chlamydia Infections / Q000382:microbiology*; D002692:Chlamydia trachomatis / Q000276:immunology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D000292:Pelvic Inflammatory Disease / Q000382:microbiology*
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial