[Uric acid and arterial hypertension. III. Effect of nifedipine on serum uric acid level and its renal excretion in primary arterial hypertension].
In sixteen patients with moderate essential hypertension the effects of 10-day nifedipine treatment on serum uric acid and renal excretion of uric acid were evaluated. Neither serum uric acid nor clearance and fractional excretion of uric acid changed significantly during treatment with nifedipine. Positive correlation between fall in systolic arterial pressure and decrease of serum uric acid in hypertensive patients treated with nifedipine was found.
Tykarski
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Kliniki Nadciśnienia Tetniczego Instytutu Kardiologii AM w Poznaniu.
D000328:Adult; D004231:Diuresis / Q000187:drug effects / Q000502:physiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000503:physiopathology*; D007668:Kidney / Q000187:drug effects / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors; D014527:Uric Acid / Q000097:blood / Q000378:metabolism* / Q000652:urine
D014527:Uric Acid; D009543:Nifedipine
Kwas moczowy a nadciśnienie tetnicze. III. Wpływ nifedypiny na stezenie kwasu moczowego w surowicy i jego nerkowe wydalanie w nadciśnieniu tetniczym pierwotnym.