title: New mechanism of melanosomes transport into hair of lambs of different breeds and genotypes.
abstract: By light microscopic investigation of skin and wool specimens of newborn lambs, we discovered a previously unknown mechanism for melanosomes transport in the process of dermal papilla melanocytes regular mitosis and migration into the hair shaft. This mechanism plays a great role in hair pigmentation especially in dominant (ED/ED) and recessive (Aa/Aa) black lambs of all investigated breeds. The rate of pigment cell mitosis, proliferation, and migration differs greatly in lambs of investigated color genotypes. In black genotypes the rate of melanocyte mitosis is very high and is approximately the same as in the hair bulb matrix cells, whereas in brown and red genotypes this rate is much lower. Melanocyte mitosis in the light red and tan groups was not found.
authors.affiliation: Department of Genetics, Academy of Sciences of the Tajik, SSR, Dushanbe.
authors.forename: M L
authors.initials: ML
authors.lastname: Rachkovsky
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000235:genetics / Q000502:physiology; D001692:Biological Transport; D002465:Cell Movement; D003594:Cytoplasmic Granules; D006197:Hair / Q000502:physiology*; D006200:Hair Color / Q000235:genetics / Q000502:physiology; D015603:Keratinocytes / Q000502:physiology*; D008544:Melanocytes / Q000502:physiology*; D008938:Mitosis; D012756:Sheep / Q000235:genetics / Q000502:physiology*