title: Tetracycline resistance in Moraxella (Branhamella) catarrhalis: demonstration of two clonal outbreaks by using pulsed-field gel electrophoresis.
abstract: Two tetracycline-resistant (Tcr) Moraxella (Branhamella) catarrhalis strains from England were compared with two previously characterized Tcr Texas strains. Both pairs carried the Tet B determinant, which was nontransferable. Pulsed-field gel electrophoresis of their genomic DNA restriction fragments demonstrated that the strains from the same area were identical (clonal); however, the Texas and English strains differed from each other.
authors.affiliation: Department of Pathobiology, University of Washington, Seattle 98195.
authors.forename: M C
authors.initials: MC
authors.lastname: Roberts
authors.forename: Y J
authors.initials: YJ
authors.lastname: Pang
authors.forename: R C
authors.initials: RC
authors.lastname: Spencer
authors.forename: T G
authors.initials: TG
authors.lastname: Winstanley
authors.forename: B A
authors.initials: BA
authors.lastname: Brown
authors.forename: R J
authors.initials: RJ
authors.lastname: Wallace
mesh_terms: D004269:DNA, Bacterial / Q000032:analysis; D004196:Disease Outbreaks; D016521:Electrophoresis, Gel, Pulsed-Field; D006801:Humans; D001936:Moraxella catarrhalis / Q000187:drug effects*; D016870:Neisseriaceae Infections / Q000382:microbiology; D010957:Plasmids; D013753:Tetracycline Resistance / Q000235:genetics
chemical_list: D004269:DNA, Bacterial