[Study of components of standard samples of polyene macrolide antibiotics by the methods of high performance liquid chromatography and SIEAP mass spectrometry].
The component composition of reference samples of polyenic macrolide antibiotics such as nystatin, mycoheptin, amphotericin B and levorin was studied by HPLC and chromatographic mass spectrometry in comparison to the WHO standards. It was shown that the samples were close by their component composition to the analogous samples of the WHO standards.
Mitrofanova
V G
VG
Mirgorodskaia
O A
OA
Derzhavets
A A
AA
Matveeva
E R
ER
Shenin
Iu D
IuD
Morgunova
A F
AF
D000666:Amphotericin B / Q000032:analysis* / Q000592:standards; D000900:Anti-Bacterial Agents / Q000032:analysis* / Q000592:standards; D002174:Candicidin / Q000032:analysis* / Q000592:standards; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D013058:Mass Spectrometry / Q000379:methods; D008970:Molecular Weight; D009761:Nystatin / Q000032:analysis* / Q000592:standards; D011090:Polyenes / Q000032:analysis / Q000592:standards; D012015:Reference Standards; D014944:World Health Organization
D000900:Anti-Bacterial Agents; D011090:Polyenes; D009761:Nystatin; D002174:Candicidin; D000666:Amphotericin B; C008567:mycoheptin
Izuchenie komponentnogo sostava standartnykh obraztsov polienovykh makrolidnykh antibiotikov metodom vysokoéffektivnoĭ zhidkostnoĭ khromatografii i mass-spektrometrii ERIAD.