[Is there a drug treatment approach for prevention and therapy of fat embolism syndrome?].
The pathogenesis of fat embolism has been subject to considerable debate ever since it was first described by Zenker in 1864. The clinical course, management and pathophysiology of a typical case are described. As no single causative factor has been implied in the development of fat embolism, its therapy and prevention primarily involves the adequate treatment of shock and of the underlying traumatic lesions.
Schröder
D
D
Chirurgische Klinik, Krankenhaus Nordwest, Frankfurt/Main.
Buttenschön
K
K
Herrmann
F
F
Brede
S
S
D000328:Adult; D003131:Combined Modality Therapy; D003422:Critical Care / Q000379:methods*; D004620:Embolism, Fat / Q000188:drug therapy*; D005260:Female; D005264:Femoral Fractures / Q000601:surgery*; D005594:Fracture Fixation, Intramedullary; D006801:Humans; D010713:Phosphatidylcholines / Q000008:administration & dosage*; D011183:Postoperative Complications / Q000188:drug therapy*; D011655:Pulmonary Embolism / Q000188:drug therapy*; D012128:Respiratory Distress Syndrome / Q000188:drug therapy; D013978:Tibial Fractures / Q000601:surgery*
D010713:Phosphatidylcholines; C005152:lipostabil
Gibt es einen medikamentösen Ansatz zur Prophylaxe und Therapie des Fettemboliesyndroms?