Adenosine deaminase, Ada, is in mouse chromosome 2H3, and is not allelic with wasted, wst.
The adenosine deaminase locus (Ada) in the mouse has been localized by in situ hybridization to band 2H3. Linkage analysis of backcross data has shown that Ada is 13.8 +/- 2.7 cM from the coat texture mutant, ragged, Ra. From the results of earlier work (Abbott, C. M., et al., Proc. Natl. Acad. Sci. USA 83:693, 1986), it had been suggested that wst was a low-activity allele of Ada, but this cannot be so because Ada and wst have been found to be nonallelic.
Abbott
C M
CM
MRC Radiobiology Unit, Chilton, Didcot, U.K.
Evans
E P
EP
Burtenshaw
M
M
Ball
S T
ST
Skidmore
C J
CJ
Jones
J
J
Peters
J
J
D000243:Adenosine Deaminase / Q000235:genetics*; D000483:Alleles; D000818:Animals; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D008040:Genetic Linkage; D051379:Mice / Q000235:genetics*; D008809:Mice, Inbred C3H / Q000235:genetics; D008810:Mice, Inbred C57BL / Q000235:genetics; D008817:Mice, Mutant Strains / Q000235:genetics; D009693:Nucleic Acid Hybridization
D000243:Adenosine Deaminase