Non-ribosomal peptide synthesis.
Many peptides are synthesized by the multienzyme thiotemplate mechanism. This is catalyzed by large, multifunctional enzymes called peptide synthetases. Recent studies have focused on elucidating the primary structure of the peptide synthetases and defining their functional domains. These are essential first steps in the detailed mutational analysis of peptide synthetase function.
Zuber
P
P
Louisiana State University Medical Center, Shreveport.
D004252:DNA Mutational Analysis; D005798:Genes, Bacterial; D005800:Genes, Fungal; D010453:Peptide Synthases / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism
D010453:Peptide Synthases