[Hodgkin's lymphoma with nodular sclerosis. A report of a case with an unusual sternal location at the onset].
The authors report the case of a boy, 9 years old, with a mass in the sternum and the anterior region of the mediastinum. A biopsy of the sternal mass was performed and demonstrated a Hodgkin disease variety nodular sclerosis. The disease was classified as stage III A after that two lymph nodes on the right side of the groin were revealed by lymphography. Therapy consisted of 6 alternate MOPP/ABVD cycles, followed by mantle and inverted Y field radiotherapy for a total of 25 Cg and 5 Cg booster on a sternum. During chemotherapy there was a complete regression of the disease in all sites. At present the patient is healthy and in complete remission and "off therapy", with a follow-up of 32 months. The most interesting aspect of this case is the sternum involvement as the initial manifestation of the nodular sclerosing form of Hodgkin's disease.
Miano
C
C
Divisione di Ematologia Pediatrica, Ospedale Bambino Gesù, Roma, Italia.
Lombardi
A
A
Russo
L A
LA
Ceci
A
A
Baronci
C
C
Bonaldi
U
U
Rosati
D
D
D001706:Biopsy; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000473:pathology; D002648:Child; D006689:Hodgkin Disease / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D012598:Sclerosis / Q000473:pathology; D013249:Sternum / Q000473:pathology*
Linfoma di Hodgkin a sclerosi nodulare. Descrizione di un caso con insolita localizzazione sternale all'esordio.