Two new trichothecenes from Fusarium sporotrichioides.
Two new trichothecenes, 8-n-pentanoylneosolaniol and 8-n-hexanoylneosolaniol, were isolated from corn grits cultured with Fusarium sporotrichioides. The structures of these compounds were elucidated using gc-ms, nmr, X-ray crystallography, and other spectroscopic techniques. Seven known trichothecenes were also isolated, and the relative cytotoxicity of these nine trichothecenes in cultured baby hamster kidney (BHK-21) cells was determined.
Bekele
E
E
Veterinary Medical Diagnostic Laboratory, University of Missouri, Columbia 65211.
Rottinghaus
A A
AA
Rottinghaus
G E
GE
Casper
H H
HH
Fort
D M
DM
Barnes
C L
CL
Tempesta
M S
MS
D000818:Animals; D002478:Cells, Cultured; D006224:Cricetinae; D005670:Fusarium / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009183:Mycotoxins / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D014255:Trichothecenes / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity
D009183:Mycotoxins; D014255:Trichothecenes; C073624:8-pentanoylneosolaniol; C073623:8-hexanoylneosolaniol