[Avermectins: biotechnological features of the producing strain of Streptomyces avermitilis VKM As 1301].
The monosporic plating of the avermectin-producing strain Streptomyces avermitilis VKM Ac-1301 with low activity showed the heterogeneity of the population. By selection of natural mutants the authors obtained a strain synthesizing up to 60 micrograms avermectin B1 per ml of culture liquid. The maximum avermectin yield was observed in the medium containing 7% glucose after 100-120 h of culture growth.
Chermenskiĭ
D N
DN
Adanin
V M
VM
Driniaev
V A
VA
Kovalev
V N
VN
Golovleva
L A
LA
D003470:Culture Media; D005947:Glucose / Q000378:metabolism; D007559:Ivermectin / Q000031:analogs & derivatives* / Q000378:metabolism; D013302:Streptomyces / Q000254:growth & development / Q000378:metabolism*
D003470:Culture Media; D007559:Ivermectin; C019264:avermectin; D005947:Glucose
Avermektiny: biotekhnologicheskie osobennosti shtamma-produtsenta Streptomyces avermitilis VKM As1301.