title: [Critical evaluation of dialytic adequacy].
abstract: At present it is difficult to define the concept of dialysis adequacy correctly. The paper analyses two of the parameters which are commonly used for this purpose: Kt/V and the behaviour of Beta-2 microglobulin, molecular antipodes for the removal of uremic toxins. A critical analysis is made of the validity of methods to calculate the former and the reliability of the latter. Attention is focused on the fact that an evaluation of dialysis adequacy cannot be limited to theoretical observations regarding the removal of solutes, but must also be integrated by the clinical observation of patients and the commencement of support therapy (pharmacological and/or nutritional and/or physical). In this manner, the adequate treatment of the uremic patients is not entrusted solely to the technological component.
authors.affiliation: Divisione di Nefrologia, Ospedale S. Croce, Cuneo.
authors.forename: P M
authors.initials: PM
authors.lastname: Ghezzi
mesh_terms: D000465:Algorithms; D005069:Evaluation Studies as Topic; D006801:Humans; D008567:Membranes, Artificial; D006435:Renal Dialysis / Q000295:instrumentation; D014508:Urea / Q000097:blood; D014511:Uremia / Q000097:blood* / Q000628:therapy; D001613:beta 2-Microglobulin / Q000032:analysis
chemical_list: D008567:Membranes, Artificial; D001613:beta 2-Microglobulin; D014508:Urea
vernacular_title: Esame critico dell'adeguatezza dialitica.