Fatal trichosporonosis is not related to tolerance to amphotericin B.
A case of disseminated trichosporonosis in a 45-year-old female suffering from acute lymphocytic leukaemia is reported. The patient died of that mycosis despite of therapy with amphotericin B for which the pathogen had been proven susceptible in vitro.
Alballaa
S
S
Division of Infectious Diseases, Vancouver General Hospital, British Columbia, Canada.
Bryce
E A
EA
Roberts
F J
FJ
Sekhon
A
A
D000666:Amphotericin B / Q000494:pharmacology* / Q000627:therapeutic use; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy* / Q000209:etiology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D014250:Trichosporon / Q000187:drug effects*
D000666:Amphotericin B