title: Intrathecal baclofen for severe spasticity: five years experience.
abstract: Severe spasticity is a major problem in the rehabilitation of patients with dysfunction of the spinal cord or cerebral hemispheres. Oral baclofen is often effective. However, in patients with severe spasticity adequate control may not be obtained from oral therapy with the drug. Over the past 5 years we have developed a program for the use of intrathecal baclofen for severe spasticity, and in relation to this discuss patient assessment, practical aspects of drug administration, complications of therapy and patient benefits. Continuous intrathecal baclofen is a safe and effective adjunct to physical therapy in the management of patients with severe spasticity.
authors.affiliation: Department of Neurology, Royal Perth Hospital.
authors.forename: E G
authors.initials: EG
authors.lastname: Stewart-Wynne
authors.forename: P L
authors.initials: PL
authors.lastname: Silbert
authors.forename: S
authors.initials: S
authors.lastname: Buffery
authors.forename: D
authors.initials: D
authors.lastname: Perlman
authors.forename: E
authors.initials: E
authors.lastname: Tan
mesh_terms: D000328:Adult; D001418:Baclofen / Q000008:administration & dosage*; D002408:Catheters, Indwelling / Q000009:adverse effects; D006801:Humans; D007278:Injections, Spinal; D008875:Middle Aged; D009128:Muscle Spasticity / Q000188:drug therapy* / Q000503:physiopathology; D011788:Quality of Life
chemical_list: D001418:Baclofen