title: UK external quality assessment scheme for immunoassays in endocrinology.
abstract: UK EQAS provide the UK with a comprehensive system for EQA in endocrinology, as well as in other aspects of clinical chemistry and laboratory medicine. UK EQAS in endocrinology are scientifically designed to yield an objective assessment of participants' performance and stimulate improvements in between-laboratory agreement. The design uses appropriate specimens, based on liquid human serum and prepared with minimal processing and additives in the organising centres to enable detailed study of recovery and other important factors. Target values are validated by reproducibility on repeated distribution and by recovery and parallelism studies. Reports are presented informatively, and emphasise the cumulative scoring system (bias and variance) for performance assessment. Computerised data processing and data presentation form an integral part of these schemes, and a common core computing system is in use throughout these UK EQAS. Participants receive advice and assistance in the interpretation of performance data and, when appropriate, in the resolution of problems.
authors.affiliation: UK EQAS for Thyroid-related Hormones, Wolfson Research Laboratories, Queen Elizabeth Hospital, Birmingham, UK.
authors.forename: F
authors.initials: F
authors.lastname: MacKenzie
authors.forename: D G
authors.initials: DG
authors.lastname: Bullock
authors.forename: J G
authors.initials: JG
authors.lastname: Ratcliffe
mesh_terms: D002624:Chemistry, Clinical / Q000592:standards; D004704:Endocrinology / Q000592:standards*; D006728:Hormones / Q000032:analysis* / Q000276:immunology; D006801:Humans; D007118:Immunoassay / Q000592:standards*; D007753:Laboratories / Q000592:standards; D010455:Peptides / Q000032:analysis / Q000276:immunology; D011786:Quality Control; D012984:Software; D013256:Steroids / Q000032:analysis / Q000276:immunology; D013963:Thyroid Hormones / Q000032:analysis / Q000276:immunology; D006113:United Kingdom
chemical_list: D006728:Hormones; D010455:Peptides; D013256:Steroids; D013963:Thyroid Hormones