[The role of the rate of sodium-lithium countertransport of the erythrocytes in arterial hypertension].
The present work is concerned with the role of the velocity of Na+/Li(+)-countertransport of red blood cells (as an indicator of the function of cellular membranes) in the development of arterial hypertension under conditions of a populational study. A relationship is demonstrated between the velocity of Na+/Li(+)-countertransport and the sex, arterial pressure, body mass index, and blood serum triglycerides. The high velocity of Na+/Li(+)-countertransport is encountered in 25% of the population, being responsible for about 30% of all cases of arterial hypertension. Taking into consideration the modern multifactorial theory of the genesis of arterial hypertension, the high velocity of Na+/Li(+)-countertransport should be viewed as a definite disease pattern (one of several) and as a risk factor of arterial hypertension in women (the data of the prospective part of the study).
Kobal'
A M
AM
Britov
A N
AN
Orlov
S N
SN
Pokudin
N I
NI
Grishenkov
E A
EA
Deev
A D
AD
D000328:Adult; D001692:Biological Transport; D001794:Blood Pressure; D004910:Erythrocyte Membrane / Q000378:metabolism*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000453:epidemiology / Q000209:etiology; D008094:Lithium / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D012964:Sodium / Q000097:blood*
D008094:Lithium; D012964:Sodium
O roli skorosti natriĭ-litievogo protivotransporta éritrotsitov pri arterial'noĭ gipertenzii.