[The effects of ciprofloxacin and ofloxacin on the cellular and humoral immune response in mice].
The effects of a 7 days chemotherapy with ciprofloxacin or ofloxacin on the cellular and humoral immune responses in albino mice were studied. The non-toxic doses of the drugs (10 or 30 mg/kg/day) were used. The delayed-type hypersensitivity reaction to sheep blood cells and skin biopsy were evaluated for cellular immune response. The complement fixation method was applied for the determination of the humoral immune response. Both drugs increased the cellular and humoral immune responses.
Usluer
G
G
Anadolu Universitesi, Fakültesi Infeksiyon Hastaliklari Anabilim Dali.
Ulak
G
G
Erol
K
K
Gürer
F
F
Cingi
M I
MI
Ozdemir
M
M
Alpan
R S
RS
D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D002939:Ciprofloxacin / Q000494:pharmacology*; D003168:Complement Fixation Tests; D006968:Hypersensitivity, Delayed; D007111:Immunity, Cellular / Q000187:drug effects*; D051379:Mice; D015242:Ofloxacin / Q000494:pharmacology*
D002939:Ciprofloxacin; D015242:Ofloxacin
Siprofloksasin ve ofloksasinin farelerde hücresel ve hümoral immün cevap üzerine etkileri.