Pregnancy and postpartum after kidney transplantation and cyclosporin therapy--review of the literature adding a new case.
The number of pregnancies after renal transplantation and immunosuppression is relative low. Since the introduction of a most effective medication, Cyclosporin A, there is not only an increasing improvement of the transplantation results, but there are also more reports on successfully concluded pregnancies. This report pertains to a 26-year old primigravida, whose pregnancy progressed without severe complications until the 33rd week of gestation. Then a sudden and rapidly worsening preeclampsia led to admission and delivery. The postoperative period was complicated by a severe septical shock. The literature is reviewed. Problems following pregnancy after kidney transplantation and triple immunotherapy with Cyclosporin A treatment are pointed out.
Bung
P
P
Department of Gynaecology and Obstetrics, University of Bonn, Fed. Rep. of Germany.
Molitor
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D
D000328:Adult; D001379:Azathioprine / Q000627:therapeutic use; D002585:Cesarean Section; D016572:Cyclosporine / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000276:immunology; D011225:Pre-Eclampsia / Q000209:etiology; D011239:Prednisolone / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology*; D011263:Pregnancy Trimester, Third; D011645:Puerperal Infection / Q000209:etiology
D016572:Cyclosporine; D011239:Prednisolone; D001379:Azathioprine