[Endocarditis caused by Candida parapsilosis after total correction of tetralogy of Fallot. Medico-surgical treatment].
Three children with Candida Parapsilosis endocarditis after total surgical correction for Tetralogy of Fallot, are reported. Blood cultures became negative in one child with amphotericin-B and in the other two with Ketoconazole, before reoperation for septal patch replacement. Oral therapy with Ketoconazole continued for a total of 24 months, and during a mean follow-up of 36 months no side effects or reinfection occurred. Medical and surgical conjoined therapy, with surgical timing decided on clinical and laboratorial grounds, were important for good results and cure.
Macedo
A
A
Serviço de Cardiologia Pediátrica, Hospital de Santa Marta, Lisboa.
Agualusa
A
A
Kaku
S
S
Lima
M
M
Cabrita
J
J
Bento
R
R
Sampayo
F
F
D002177:Candidiasis / Q000628:therapy*; D003131:Combined Modality Therapy; D004696:Endocarditis / Q000382:microbiology / Q000628:therapy*; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007654:Ketoconazole / Q000627:therapeutic use; D011183:Postoperative Complications / Q000382:microbiology*; D013771:Tetralogy of Fallot / Q000601:surgery*
D007654:Ketoconazole
Endocardite por Cândida parapsilosis após correcção total de tetralogia de Fallot. Tratamento médico-cirúrgico.