[Sugar residues of glycoconjugates in the olfactory epithelium of the human fetus: histochemical study using peroxidase-conjugated lectins].
The oligosaccharide content of glycoconjugates was studied at the olfactory epithelium of human fetuses ranging from 8 to 12 weeks of gestation by mean of peroxidase labelled lectins (DBA, PNA, WGA, SBA, ConA, LTA, UEA I). The main results demonstrated that: 1-The olfactory epithelium (olfactory cells, supporting cells and basal cells) was generally characterized by different amount of a-D-mannose, a-D-galactosamine, a-D-glucose, D-galactose-(beta 1-3)-N-acetyl-galactosamine, sialic acid and a-L-fucose. 2-At the 11th-12th week of gestation the largest amount of sugar residues was detected at the olfactory cells and at some basal cells. 3-At the 12th week of gestation, UEA I may be considered a specific marker of the olfactory cells in different stages of development.
Gheri
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Dipartimento di Anatomia umana e Istologia Università di Firenze.
Gheri Bryk
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Balboni
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GC
D002240:Carbohydrate Sequence; D002454:Cell Differentiation; D004848:Epithelium / Q000737:chemistry; D005865:Gestational Age; D006001:Glycoconjugates / Q000032:analysis*; D006735:Horseradish Peroxidase; D006801:Humans; D037102:Lectins; D008969:Molecular Sequence Data; D009831:Olfactory Mucosa / Q000737:chemistry / Q000166:cytology / Q000196:embryology*; D009844:Oligosaccharides / Q000032:analysis*
D006001:Glycoconjugates; D037102:Lectins; D009844:Oligosaccharides; D006735:Horseradish Peroxidase
I residui zuccherini dei glicoconiugati nell'epitelio olfattivo di feti umani: studio istochimico con lectine coniugate a perossidasi.