Twenty-four-hour patterns of sleep in depression.
Alterations of nocturnal sleep have been widely described in affective disorders. However, little is known about putative daytime sleep and to what extent daytime sleep could interfere with nocturnal sleep. The goal of this study was to investigate 24-hr sleep patterns in 12 depressed patients hospitalized for a major depressive disorder and in 10 control subjects studied under the same experimental conditions. Patients and controls were free to sleep whenever they chose, and sleep recordings were performed using the Oxford Medilog System during 60 hr. Daytime sleep episodes were detected in 50% of the patients and in 60% of the controls. Patients took naps at various times of the day, whereas controls napped in the early afternoon, during the well-known "postlunch dip". Thus daytime sleep prevalence was similar in both groups; however, the biphasic distribution of sleep observed in controls disappeared in the patients. Napping did not affect subsequent nocturnal sleep in either group.
Kerkhofs
M
M
Department of Psychiatry, Erasme Hospital, Free University of Brussels, Belgium.
Linkowski
P
P
Lucas
F
F
Mendelwicz
J
J
D000328:Adult; D001143:Arousal / Q000502:physiology; D001921:Brain / Q000503:physiopathology; D002940:Circadian Rhythm / Q000502:physiology*; D003866:Depressive Disorder / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic; D011930:Reaction Time / Q000502:physiology; D012894:Sleep Stages / Q000502:physiology*; D014851:Wakefulness / Q000502:physiology