[Late results of the treatment of advanced Hodgkin's disease by the MOPP/COPP programs (chlormethine or cyclophosphamide, vincristine, procarbazine and prednisone)].
The results of the treatment with MOPP/COPP program for 114 patients with advanced Hodgkin's disease are presented. Complete remission has been achieved in 74 patients (65%). Thirty four of them (30%) are still remaining in first remission. The relapse of disease was observed in 37 patients, in 16 of them during first 24 months of follow-up. Three patients were lost of observation. The analysis of these unsatisfactory long-term results suggests that more effective management policies for patients with advanced Hodgkin's disease are needed.
Błasińska-Morawiec
M
M
II Kliniki Chorób Wewnetrznych A.M.
Płuzańska
A
A
Krykowski
E
E
Robak
T
T
Mrówka
I
I
D000293:Adolescent; D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000008:administration & dosage; D005260:Female; D006689:Hodgkin Disease / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008297:Male; D008466:Mechlorethamine / Q000008:administration & dosage; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000209:etiology*; D009367:Neoplasm Staging; D011241:Prednisone / Q000008:administration & dosage; D011344:Procarbazine / Q000008:administration & dosage; D013997:Time Factors; D014750:Vincristine / Q000008:administration & dosage
D011344:Procarbazine; D008466:Mechlorethamine; D014750:Vincristine; D003520:Cyclophosphamide; D011241:Prednisone
Odległe wyniki leczenia zaawansowanej ziarnicy złośliwej według programu MOPP/COPP (chlormetyna lub cyklofosfamid, winkrystyna, prokarbazyna, prednizon).