Muscle cell death. Ultrastructural differences between muscle cell necrosis and apoptosis.
The morphology and incidence of muscle cell necrosis and apoptosis are presented. Necrosis which occurs as a massive tissue damage is structurally characterized by swelling of the muscle cell and disruption of cellular components. Apoptosis, on the other hand, is a process of active cellular self-destruction. It shows characteristic sequence of muscle cell shrinkage, which is ending in transformation of each muscle cell into compact apoptotic bodies that in turn are phagocytized by adjacent cells or macrophages.
Fidziańska
A
A
Department of Neurology, School of Medicine, Warsaw.
Kamińska
A
A
Glinka
Z
Z
D001343:Autophagy / Q000502:physiology*; D016923:Cell Death; D006801:Humans; D008854:Microscopy, Electron; D008931:Mitochondria, Muscle / Q000648:ultrastructure; D009132:Muscles / Q000276:immunology / Q000473:pathology* / Q000648:ultrastructure; D009210:Myofibrils / Q000648:ultrastructure; D009336:Necrosis; D009468:Neuromuscular Diseases / Q000276:immunology / Q000473:pathology*