Out-patient peritoneal lavage cytology in the detection of residual epithelial ovarian cancer.
Peritoneal lavage fluid cytology was performed in 87 out-patients with histologically proven epithelial ovarian cancer undergoing primary management. A total of 246 peritoneal lavages were attempted, usually with temporary cannulae (n = 229). From these, 184 samples were obtained, of which 156 (85%) were suitable for cytological analysis. The sensitivity of peritoneal lavage fluid cytology in 67 patients with known residual disease was 57% whereas serum CA 125 levels were elevated in 58 (87%). Pre- and post-treatment peritoneal lavage fluid cytology had prognostic value, but this was less than that of serum CA 125 measurements.
Redman
C W
CW
West Midlands CRC Clinical Trials Unit, Queen Elizabeth Medical Centre, Birmingham, UK.
Chapman
S E
SE
Chan
S Y
SY
Buxton
E J
EJ
Blackledge
G
G
Luesley
D M
DM
D000328:Adult; D000553:Ambulatory Care / Q000379:methods; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000097:blood; D003581:Cytodiagnosis / Q000379:methods; D004848:Epithelium / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D010051:Ovarian Neoplasms / Q000097:blood / Q000473:pathology*; D010533:Peritoneal Lavage; D011379:Prognosis; D012680:Sensitivity and Specificity
D015295:Antigens, Tumor-Associated, Carbohydrate