Plasminogen activator in human breast cancer cytosols: revisited after five years.
The outcome after five years in 63 women with breast cancer was correlated with biochemical parameters (estrogen and progesterone receptors, plasminogen activator activity) determined in the cytosol of tumour specimens obtained at surgery. The information from tumour cell products and their regulatory proteins may provide additional prognostic indicators, independent of subsequent treatment.
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Sunnybrook Health Science Centre, University of Toronto, Ontario, Canada.
Sutherland
D J
DJ
Szalai
J P
JP
Kellen
J A
JA
D001943:Breast Neoplasms / Q000737:chemistry* / Q000601:surgery; D003600:Cytosol / Q000737:chemistry*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D010960:Plasminogen Activators / Q000032:analysis*; D013223:Statistics as Topic; D010959:Tissue Plasminogen Activator / Q000032:analysis; D016896:Treatment Outcome; D014568:Urokinase-Type Plasminogen Activator / Q000032:analysis
D010960:Plasminogen Activators; D010959:Tissue Plasminogen Activator; D014568:Urokinase-Type Plasminogen Activator