title: [Significance of molecular genetics in oncology].
abstract: The development of Molecular Biology in recent years has had a profound impact in all Medical research fields and has been particularly important for the progress of oncology research. A whole body of new methodologies has been specifically designed to investigate the structure and the expression of cellular genes. This new field has rapidly extended far beyond basic research, with applications that are becoming exceedingly relevant in the resolution of many important clinical problems. As a consequence of a better understanding of the biology of neoplastic cells, more rationale therapeutic approaches as well as new diagnostic tools could be developed. The objective of the present work is to discuss the multiple contributions of Molecular Biology in research, diagnosis and therapy in oncology.
authors.affiliation: Instituto de Histologia e Embriologia, Faculdade de Medicina de Lisboa.
authors.forename: L
authors.initials: L
authors.lastname: Parreira
mesh_terms: D002455:Cell Division; D016147:Genes, Tumor Suppressor; D006801:Humans; D008967:Molecular Biology; D009369:Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D009857:Oncogenes; D011518:Proto-Oncogene Proteins; D012190:Retroviridae
chemical_list: D011518:Proto-Oncogene Proteins
vernacular_title: Importância da genética molecular em oncologia.