[Scedosporium inflatum, a new pathogenic fungus. Report of 2 cases with a fatal outcome].
Scedosporium inflatum is a newly described human pathogen, their infections primarily involved musculoskeletal tissues. We report 2 fatal cases with disseminated S. inflatum infections in Spanish patients. The fungus was isolated from blood in both cases. Amphotericin B treatment was ineffective. In vitro susceptibility testing of one isolate against 7 antifungal agents is done. These cases illustrate the need to remain vigilant for this new emerging pathogen.
Guarro
J
J
Unidad de Microbiología, Facultad de Medicina, Universidad de Barcelona, Reus, Tarragona.
Gaztelurrutia
L
L
Marín
J
J
Bárcena
J
J
D000368:Aged; D000935:Antifungal Agents / Q000494:pharmacology / Q000627:therapeutic use; D002648:Child; D004352:Drug Resistance, Microbial; D005260:Female; D016469:Fungemia / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008590:Meningoencephalitis / Q000188:drug therapy / Q000382:microbiology*; D003904:Mitosporic Fungi / Q000187:drug effects / Q000302:isolation & purification / Q000472:pathogenicity*; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications
D000935:Antifungal Agents
Scedosporium inflatum, un nuevo hongo patógeno. A propósito de dos casos con desenlace fatal.