title: Enzymatic manipulation of protecting groups: more than deprotection.
abstract: Recent developments in the enzymatic manipulation of protecting groups are reviewed. The application of enzymes opens new alternatives in the methodics of peptide synthesis. The following topics are dealt with: 1. New combinations of protecting groups 2. Simultaneous deprotections 3. Enzymatic regiospecificity versus chemical selectivity 4. Racemization control and enantioselective deprotection 5. N- and O-glycosylated amino acid and peptide derivatives.
authors.affiliation: Institute of Biochemistry, Medical Faculty Martin-Luther-University, Halle, FRG.
authors.forename: P
authors.initials: P
authors.lastname: Hermann
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000737:chemistry; D004798:Enzymes; D006031:Glycosylation; D008969:Molecular Sequence Data; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D013379:Substrate Specificity
chemical_list: D000596:Amino Acids; D004798:Enzymes; D010455:Peptides