[The heterogeneity of the alveolar macrophages of guinea pigs immunized subcutaneously with a vaccinal strain of Yersinia pestis].
The study of alveolar macrophages obtained from guinea pigs at different periods after the subcutaneous immunization with Y. pestis vaccine strain has revealed the heterogeneity of these macrophages in their bactericidal activity with respect to Y. pestis and in their resistance to the cytopathic action of this microorganism, as well as in the content of lysosomes and in the expression of receptors on the cell surface. The study has shown that subcutaneous immunization does not lead to the redistribution of subpopulations and to changes in their digestive activity.
Vasil'eva
G I
GI
Gamleshko
Kh P
KhP
Tkachenko
L N
LN
Kiseleva
A K
AK
Doroshenko
A P
AP
D000818:Animals; D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000276:immunology*; D002469:Cell Separation; D003176:Complement C3 / Q000276:immunology; D006168:Guinea Pigs; D007114:Immunization / Q000379:methods; D007279:Injections, Subcutaneous; D008247:Lysosomes / Q000276:immunology; D008262:Macrophage Activation / Q000276:immunology; D008264:Macrophages / Q000276:immunology*; D010587:Phagocytosis / Q000276:immunology; D011650:Pulmonary Alveoli / Q000276:immunology*; D011951:Receptors, Complement / Q000276:immunology; D011961:Receptors, Fc / Q000276:immunology; D013997:Time Factors; D015010:Yersinia pestis / Q000276:immunology*
D001428:Bacterial Vaccines; D003176:Complement C3; D011951:Receptors, Complement; D011961:Receptors, Fc
Geterogennost' al'veoliarnykh makrofagov morskikh svinok pri podkozhnoĭ immunizatsii vaktsinnym shtammom Yersinia pestis.