Dynamics of excretion (14C) bromfenvinphos in rats and dogs.
The dynamics of excretion of 14C in rat and dog after a single oral administration of 14C-bromfenvinphos was investigated. The level of radioactivity in urine, faeces and expired air in rats and in urine and faeces in dogs and the level of 14C in rat, depending on the dose and on the position of the labeling of the bromfenvinphos molecule (14C-vinyl) and (14C-ethyl), were determined. Also, the decay of 14C in blood and the retention degree of radioactivity in selected rat tissues were examined.
Ochyński
J
J
Department of Toxicological Chemistry, Medical Academy, Lublin, Poland.
D000818:Animals; D002709:Chlorfenvinphos / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D004285:Dogs; D005260:Female; D007306:Insecticides / Q000493:pharmacokinetics*; D008297:Male; D008657:Metabolic Clearance Rate / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D013045:Species Specificity
D007306:Insecticides; C014369:bromfenvinphos; D002709:Chlorfenvinphos