[The dynamic modification of aseptic inflammation with sodium oxybutyrate].
The oxybuturate sodium influence on the vessel and cells dynamics in the source of aseptic inflammation was studied. It was shown that oxybuturate sodium injection (100 mg/kg) before 30 min and after 2 and 4 hours of inflammation onset leads to suppression of microvessel reaction, reduction of macrophagic infiltrate density, decrease of macrophagic phase duration and the earliest perfection of inflammation in the whole.
Vasil'eva
L S
LS
Kuz'menko
V V
VV
Malyshev
V V
VV
D000818:Animals; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D007249:Inflammation / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D008833:Microcirculation / Q000187:drug effects / Q000473:pathology; D051381:Rats; D012978:Sodium Oxybate / Q000627:therapeutic use*; D013997:Time Factors
D012978:Sodium Oxybate
Modifikatsiia dinamiki asepticheskogo vospaleniia oksibutiratom natriia.