title: [Characterization of immunological responses to bone and cartilage xenografts].
abstract: The immunological responses to subcutaneous bone and cartilage grafts were investigated in rats using phenol oxidase, a leukocyte labelling enzyme. The resulting development of granulomas reflects a cell-mediated immunological process and is proof of the immunogenicity of bone and cartilage. This method is a new criterium for the assessment of the biocompatibility of graft and implant materials.
authors.affiliation: Institut für Biochemie des Bereiches Medizin der Martin-Luther-Universität in Halle, Saale.
authors.forename: H
authors.initials: H
authors.lastname: Schmidt
authors.forename: S
authors.initials: S
authors.lastname: Völkel
mesh_terms: D000818:Animals; D016025:Bone Transplantation / Q000009:adverse effects / Q000276:immunology*; D002356:Cartilage / Q000637:transplantation*; D015745:Granuloma, Foreign-Body / Q000209:etiology; D014442:Monophenol Monooxygenase; D051381:Rats; D014184:Transplantation, Homologous / Q000276:immunology*
chemical_list: D014442:Monophenol Monooxygenase
vernacular_title: Zur Charakterisierung der immunologischen Abwehr bei xenogener Transplantation von Knochen und Knorpel.