title: [Familial panhypopituitarism].
abstract: Two Italian brothers showed identical subsequent loss of anterior pituitary function during the first decades of their life, developing panhypopituitarism. The investigations carried out indicate that in this family the etiology is hereditary in nature, being X-chromosomal recessive or autosomal recessive, with the defect located at the level of either the hypothalamus or the pituitary gland.
authors.affiliation: Universität Essen, Abteilung Endokrinologie der Medizinischen Klinik und Kinderklinik.
authors.forename: D
authors.initials: D
authors.lastname: Hamann
authors.forename: T
authors.initials: T
authors.lastname: Olbricht
authors.forename: B P
authors.initials: BP
authors.lastname: Hauffa
authors.forename: D
authors.initials: D
authors.lastname: Reinwein
mesh_terms: D000328:Adult; D005808:Genes, Recessive; D006801:Humans; D007018:Hypopituitarism / Q000175:diagnosis / Q000235:genetics*; D008297:Male; D010375:Pedigree; D010808:Physical Examination; D010901:Pituitary Function Tests; D012729:Sex Chromosome Aberrations / Q000235:genetics*; D014960:X Chromosome
vernacular_title: Familiärer Panhypopituitarismus.