Familial biliary atresia in three siblings including twins.
We report a North American Indian family of five children in which dizygotic twin sisters and a third sibling had biliary atresia. This is in contrast to many reports of discordant biliary atresia in twins. Added to 29 previously documented cases of familial biliary atresia, these three cases support the theory that both genetic and acquired factors play a role in the pathogenesis of this disease.
Smith
B M
BM
Department of Surgery, Montreal Children's Hospital, McGill University, Quebec, Canada.
Laberge
J M
JM
Schreiber
R
R
Weber
A M
AM
Blanchard
H
H
D001656:Biliary Atresia / Q000235:genetics*; D004200:Diseases in Twins / Q000235:genetics*; D005190:Family; D005260:Female; D006801:Humans; D007198:Indians, North American / Q000235:genetics*; D007231:Infant, Newborn; D011792:Quebec; D014429:Twins, Dizygotic / Q000235:genetics*