1-O-benzyl-2-O-methyl-rac-glycerol: a key intermediate for synthesis of ether glycerolipids.
A new scheme for synthesis of saturated 1-O-alkyl-2-O-methyl-rac-glycerolipids is described. The reductive cleavage of 2-O-methyl-1,3-O,O-benzylideneglycerol with BH3.THF complex leads to 1-O-benzyl-2-O-methyl-rac-glycerol, which is a key in intermediate for the facile preparation of 1-O-alkyl-2-O-methyl-rac-glycerol and derivatives.
Pinchuk
A N
AN
Central Laboratory, Enterprise of Bacterial Preparates, Kharkov, U.S.S.R.
Mitsner
B I
BI
Shvets
V I
VI
D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D001597:Benzylidene Compounds / Q000737:chemistry*; D001894:Borohydrides / Q000737:chemistry; D004075:Diglycerides / Q000737:chemistry*; D005995:Glyceryl Ethers / Q000138:chemical synthesis*; D010084:Oxidation-Reduction
D000970:Antineoplastic Agents; D001597:Benzylidene Compounds; D001894:Borohydrides; D004075:Diglycerides; D005995:Glyceryl Ethers; C073891:2-O-methyl-1,3-O,O-benzylideneglycerol; C073890:1-O-benzyl-2-O-methylglycerol