The cellular basis of cerebellar plasticity.
Activity-dependent plasticity of the cerebellar neuronal circuitry is based on a unique synaptic plasticity known as long-term depression that occurs as a result of the interaction of two distinct types of excitatory synapses in Purkinje cells. A complex chain reaction of receptors and messengers has recently been revealed to underlie this phenomenon.
Ito
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Frontier Research Program, Saitama, Japan.
D000818:Animals; D002531:Cerebellum / Q000166:cytology* / Q000502:physiology; D006801:Humans; D009473:Neuronal Plasticity / Q000502:physiology*