title: The DVR gene family in embryonic development.
abstract: The DVR gene family consists of at least 15 members, including decapentaplegic from Drosophila, Xenopus Vg1 and the mammalian bone morphogenetic protein genes, encoding secreted proteins closely related to transforming growth factor beta Genetic and biochemical evidence supports the idea that DVR proteins form part of a cascade of extracellular signalling molecules mediating inductive tissue interactions during development.
authors.affiliation: Department of Cell Biology, Vanderbilt University Medical School, Nashville, TN 37232.
authors.forename: K M
authors.initials: KM
authors.lastname: Lyons
authors.forename: C M
authors.initials: CM
authors.lastname: Jones
authors.forename: B L
authors.initials: BL
authors.lastname: Hogan
mesh_terms: D000818:Animals; D005075:Biological Evolution; D055398:Bone Morphogenetic Protein 3; D019485:Bone Morphogenetic Proteins; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000196:embryology / Q000235:genetics; D004625:Embryo, Nonmammalian / Q000502:physiology; D004627:Embryonic Induction; D005314:Embryonic and Fetal Development / Q000235:genetics*; D005775:Gastrula / Q000502:physiology; D005786:Gene Expression Regulation; D007301:Insect Hormones / Q000235:genetics / Q000502:physiology*; D008322:Mammals / Q000196:embryology / Q000235:genetics; D008648:Mesoderm; D005810:Multigene Family; D010012:Osteogenesis / Q000235:genetics; D011506:Proteins / Q000235:genetics / Q000502:physiology*; D015398:Signal Transduction; D016212:Transforming Growth Factor beta / Q000235:genetics / Q000502:physiology*; D014982:Xenopus laevis / Q000196:embryology / Q000235:genetics
chemical_list: D055398:Bone Morphogenetic Protein 3; D019485:Bone Morphogenetic Proteins; D029721:Drosophila Proteins; D007301:Insect Hormones; D011506:Proteins; D016212:Transforming Growth Factor beta; C064196:dpp protein, Drosophila