On the robustness of regular systems of inbreeding.
Half-sib, first cousin, half nth cousin, and nth cousin mating systems are robust in that small deviations from the mating structure will not significantly alter the levels of genetic identity or effect qualitative distinctions between the models. Substitution of nearest kin in matings may either increase or decrease the level of homozygosity depending on the mating structure; the effect of a single error in the mating structure is not an accurate indicator of the equilibrium resulting from recurrent errors. Models of mixed half nth cousin or nth cousin mating show that the relative frequency of the lowest order inbred mating essentially determines the level of homozygosity. Any positive relative frequency of more distant matings will reduce the probability of identity by descent under half-sib or first cousin mating to less than 1.
Campbell
R B
RB
Department of Mathematics and Computer Science, University of Northern Iowa, Cedar Falls 50614-0441.
D000483:Alleles; D000818:Animals; D003241:Consanguinity; D006720:Homozygote; D006801:Humans; D007178:Inbreeding; D008957:Models, Genetic; D011336:Probability