[The potential hazard of the late toxic effects of the new Soviet herbicide levanil and of the semiproducts of its industrial manufacture].
Results of experimental studies in the gonado- and embryotoxicity and teratogenicity of the herbicide levanil (a chlorine derivative of phenoxipropion acid) and its synthetic semiproducts (AXBT, DXBT, OFPK) proved potential embryotoxicity and teratogenic hazards of the AXBT and DXBT semiproducts. The gonadotoxic effects of levanil and its semiproducts were also established. The compounds were characterized by a considerable degree of tropism to gonads. The revealed effects necessitate preventive measures in levanil processing and usage.
Medved'
I L
IL
Pokrovskaia
T N
TN
D000014:Abnormalities, Drug-Induced / Q000209:etiology; D000577:Amides / Q000633:toxicity*; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004622:Embryo, Mammalian / Q000187:drug effects; D005260:Female; D006540:Herbicides / Q000633:toxicity*; D006571:Heterocyclic Compounds / Q000633:toxicity*; D008297:Male; D011247:Pregnancy; D051381:Rats; D013737:Testis / Q000187:drug effects / Q000473:pathology
D000577:Amides; D006540:Herbicides; D006571:Heterocyclic Compounds; C074258:N-(aminocarbonyl)-2-ethyl-2-butenamide
O potentsial'noĭ opasnosti otdalennykh toksicheskikh éffektov novogo otechestvennogo gerbitsida levanila i poluproduktov ego promyshlennogo proizvodstva.