title: [A comparative study of the composition of the microsomal membranes of the liver, brain and skeletal muscles in vertebrates].
abstract: Phospholipid and cholesterol amounts, intrinsic protein/lipid ratios in liver, brain and skeletal muscle microsomal membranes of 14 species of vertebrate animals have been studied. No significant differences between phospholipid amounts in tissues as well as vertebrate classes have been discovered. The highest cholesterol amount has been found in brain microsomes, the smallest one in sarcoplasmic reticulum membranes. In reptile brain and muscle microsomes a higher amount of cholesterol compared to that in species of other vertebrate classes has been found. In brain membranes intrinsic protein and lipid amounts are approximately equal, while in liver and muscle microsomes a protein component predominates. Phospholipid/protein ratio is larger in brain membranes than in liver and muscle ones. Cholesterol/protein ratio reaches the highest values in microsomal membranes of reptile tissues. Brain membranes of vertebrate animals are characterized by a greater stability of protein-lipid composition than liver and muscle ones.
authors.forename: T N
authors.initials: TN
authors.lastname: Medvedeva
mesh_terms: D000663:Amphibians; D000818:Animals; D001717:Birds; D001923:Brain Chemistry; D002415:Cats; D002417:Cattle; D005399:Fishes; D007425:Intracellular Membranes / Q000737:chemistry*; D008563:Membrane Lipids / Q000032:analysis; D008565:Membrane Proteins / Q000032:analysis; D008861:Microsomes / Q000737:chemistry*; D008862:Microsomes, Liver / Q000737:chemistry*; D009132:Muscles / Q000737:chemistry*; D051381:Rats; D012104:Reptiles; D014714:Vertebrates / Q000378:metabolism*
chemical_list: D008563:Membrane Lipids; D008565:Membrane Proteins
vernacular_title: Sravnitel'noe issledovanie sostava membran mikrosom pecheni, mozga i skeletnykh myshts pozvonochnykh.