[The glycolipids of the causative agent of tularemia].
Up to 10 glycolipids were detected in F. tularensis with the use of thin-layer chromatographic techniques. These glycolipids were slime antigens of F. tularensis membrane. Attenuated F. tularensis strains were found to have defects in their glycolipid composition: in the vaccine strain glycolipid 8 was replaced by more polar lipid 8-a; the avirulent strain had only two glycolipids, and one of them was not typical for virulent strains. Considering that glycolipids differed from entero-bacterial Vi-antigen in their physical-chemical and biological properties, the suggestion was made that the use of the symbol "Vi" to denote the surface substances of F. tularensis should be abolished.
Sukhar'
V V
VV
D001426:Bacterial Proteins / Q000032:analysis; D002855:Chromatography, Thin Layer / Q000379:methods; D005604:Francisella tularensis / Q000737:chemistry* / Q000472:pathogenicity; D006017:Glycolipids / Q000032:analysis / Q000302:isolation & purification*; D006023:Glycoproteins / Q000032:analysis; D008074:Lipoproteins / Q000032:analysis; D014774:Virulence
D001426:Bacterial Proteins; D006017:Glycolipids; D006023:Glycoproteins; D008074:Lipoproteins; C025431:extracellular slime proteins, bacterial
Glikolipidy vozbuditelia tuliaremii.