Comparative morphological studies of lamb and calf Sertoli cells treated with anabolic agents.
The morphological alterations caused by anabolic steroids (oestradiol and trenbolone acetate) on the Sertoli cells of testicles in animals for human consumption (lambs and calves) were studied. The morphopathological study of the treated lambs revealed delayed development of the seminiferous tubules, which was marked by signs of immaturity and even degeneration of Sertoli cells. The main morphopathological alterations affecting the Sertoli cells in calves occurred as hyperfunction symptoms marked by increased nuclei and smooth endoplasmic reticulum.
Rodríguez Barbudo
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Department of Comparative Anatomy and Pathologic Anatomy, Veterinary Faculty, University of Córdoba, Spain.
Méndez Sánchez
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Blanco Rodríguez
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D045930:Anabolic Agents / Q000494:pharmacology*; D000818:Animals; D002417:Cattle; D002467:Cell Nucleus / Q000187:drug effects / Q000648:ultrastructure; D004721:Endoplasmic Reticulum / Q000187:drug effects / Q000648:ultrastructure; D004958:Estradiol / Q000494:pharmacology*; D008297:Male; D008854:Microscopy, Electron; D012708:Sertoli Cells / Q000166:cytology / Q000187:drug effects* / Q000648:ultrastructure; D012756:Sheep; D014204:Trenbolone Acetate / Q000031:analogs & derivatives* / Q000494:pharmacology
D045930:Anabolic Agents; D004958:Estradiol; D014204:Trenbolone Acetate