title: [Abnormalities of sexual development in Puerto Rico: status report].
abstract: Puerto Rico presents the highest incidence in the world of anomalous sexual development. The authors have collected over 3100 cases in the past 19 years. Clinical and laboratory studies suggest possible estrogenic contamination of meats and poultry products. Variation in diet provides protection to a significant number of patients. The possibility of mycotic contamination of food employed in animal husbandry by Fusarium sp., and mycotoxins capable of estrogenic effects have been suggested in a preliminary study. Private and government investigators are active in the study of the condition, but more fiscalizing action is needed. A detailed study of food components for possible contaminants determination is considered mandatory.
authors.affiliation: Escuela de Medicina de Ponce, Mayagilez, P. R. 00709.
authors.forename: A
authors.initials: A
authors.lastname: Pérez-Comas
authors.forename: C A
authors.initials: CA
authors.lastname: Saénz de Rodríguez
authors.forename: F
authors.initials: F
authors.lastname: Sánchez Lugo
mesh_terms: D000293:Adolescent; D000328:Adult; D002675:Child, Preschool; D004967:Estrogens / Q000009:adverse effects; D005260:Female; D005348:Fibrocystic Breast Disease / Q000139:chemically induced / Q000453:epidemiology*; D005506:Food Contamination; D006177:Gynecomastia / Q000139:chemically induced / Q000453:epidemiology*; D006801:Humans; D008297:Male; D010048:Ovarian Cysts / Q000139:chemically induced / Q000453:epidemiology*; D011629:Puberty, Precocious / Q000139:chemically induced / Q000453:epidemiology*; D011647:Puerto Rico / Q000453:epidemiology
chemical_list: D004967:Estrogens
vernacular_title: Anomalías de desarrollo sexual en Puerto Rico: estado de situación.