Determination of cimetidine and related impurities in pharmaceutical formulations by high-performance liquid chromatography.
The analytical characteristics of cimetidine tablets were studied. A high-performance liquid chromatographic method was developed in order to assay cimetidine and its related impurities simultaneously. A reversed-phase system and diode-array detector were used.
Betto
P
P
Istituto Superiore di Sanità, Rome, Italy.
Ciranni-Signoretti
E
E
Di Fava
R
R
D002851:Chromatography, High Pressure Liquid / Q000379:methods* / Q000706:statistics & numerical data; D002927:Cimetidine / Q000032:analysis*; D004340:Drug Contamination
D002927:Cimetidine