title: Bi-phenotypic t(9;22)-positive leukemia cell lines from a patient with acute leukemia: NALM-20, established at the onset; and NALM-21, NALM-22 and NALM-23, established after relapse.
abstract: Four leukemia cell lines; NALM-20, established at the onset of leukemia and NALM-21, -22 and -23 established at the relapse of the disease were found to be t(9;22)-positive leukemia lines having the biphenotypic feature of B cell and myeloid cell characteristics. In addition, a polyclonal Epstein-Barr virus-transformed normal B cell line, B250, was established from the peripheral blood at the onset of the disease.
authors.affiliation: Fujisaki Cell Center, Hayashibara Biochemical Laboratories, Inc.
authors.forename: Y
authors.initials: Y
authors.lastname: Matsuo
authors.forename: T
authors.initials: T
authors.lastname: Ariyasu
authors.forename: E
authors.initials: E
authors.lastname: Ohmoto
authors.forename: I
authors.initials: I
authors.lastname: Kimura
authors.forename: J
authors.initials: J
authors.lastname: Minowada
mesh_terms: D000954:Antigens, Surface; D015139:Blotting, Southern; D002051:Burkitt Lymphoma / Q000235:genetics / Q000473:pathology*; D004273:DNA, Neoplasm / Q000032:analysis; D015321:Gene Rearrangement; D006801:Humans; D007621:Karyotyping; D007951:Leukemia, Myeloid / Q000235:genetics / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010677:Philadelphia Chromosome; D014407:Tumor Cells, Cultured
chemical_list: D000954:Antigens, Surface; D004273:DNA, Neoplasm