title: [The presence of an ovarian granulocytic sarcoma concurrent with a type M2 acute myeloblastic leukemia: a case].
abstract: The authors report a case of granulosa cell tumor principally located in the ovary associated with M2 type acute myeloblastic leukemia (AML) in a trisomy 22 patients. Surgery and chemotherapy were combined with a bone marrow allograft. Frequency of granulosa cell tumor is 8 percent or less of AML cases. Diagnosis is particularly difficult when haematologic expression occurs late in the disease course. An immunohistochemical work-up is required in these cases. Aetiopathogenesis is discussed. Treatment relies essentially on chemotherapy. The prognostic is variable according to different case reports in the literature.
authors.affiliation: Service de Gynécologie-Obstétrique B, CHR Orléans.
authors.forename: S
authors.initials: S
authors.lastname: Avigdor
authors.forename: E
authors.initials: E
authors.lastname: du Rouchet
authors.forename: P
authors.initials: P
authors.lastname: Michenet
authors.forename: D
authors.initials: D
authors.lastname: Grossetti
authors.forename: V
authors.initials: V
authors.lastname: Lucas
mesh_terms: D000328:Adult; D002892:Chromosomes, Human, Pair 22; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000473:pathology*; D015470:Leukemia, Myeloid, Acute / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000473:pathology*; D014314:Trisomy
vernacular_title: Localisation ovarienne d'un sarcome granulocytaire contemporain d'une leucémie aiguë myéloblastique type M2: un cas.