Larvicidal activity of actinomycete isolate against Toxocara canis.
A soil isolate of actinomycete, strain S-70, revealing presence of plasmid(s) was placed in the genus Streptomyces according to the wall composition and morphology. The toxicity of S-70 grown on two fermentation media, glucose-asparagine broth (GAB) and malt extract-yeast extract broth (MYE), against infective larvae of Toxocara canis was assessed. The use of mortality test has provided a sensitive and reproducible bioassay. The results suggest high larvicidal activity of the Streptomyces crude products examined being highly potent when using GAB culture medium.
al-Doori
M
M
Department of Microbiology, Biological Research Centre, Scientific Research Council, Baghdad, Iraq.
al-Tae
A A
AA
Jalil
S
S
Hassan
S A
SA
D000704:Analysis of Variance; D000818:Animals; D001427:Bacterial Toxins / Q000302:isolation & purification / Q000494:pharmacology / Q000627:therapeutic use; D001681:Biological Assay; D003470:Culture Media; D004283:Dog Diseases / Q000188:drug therapy / Q000469:parasitology; D004285:Dogs; D007814:Larva / Q000502:physiology; D013302:Streptomyces / Q000737:chemistry / Q000502:physiology*; D014119:Toxocara / Q000187:drug effects / Q000502:physiology*; D014120:Toxocariasis / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary
D001427:Bacterial Toxins; D003470:Culture Media