Tetracycline resistance in Moraxella (Branhamella) catarrhalis: demonstration of two clonal outbreaks by using pulsed-field gel electrophoresis.
Two tetracycline-resistant (Tcr) Moraxella (Branhamella) catarrhalis strains from England were compared with two previously characterized Tcr Texas strains. Both pairs carried the Tet B determinant, which was nontransferable. Pulsed-field gel electrophoresis of their genomic DNA restriction fragments demonstrated that the strains from the same area were identical (clonal); however, the Texas and English strains differed from each other.
Roberts
M C
MC
Department of Pathobiology, University of Washington, Seattle 98195.
Pang
Y J
YJ
Spencer
R C
RC
Winstanley
T G
TG
Brown
B A
BA
Wallace
R J
RJ
D004269:DNA, Bacterial / Q000032:analysis; D004196:Disease Outbreaks; D016521:Electrophoresis, Gel, Pulsed-Field; D006801:Humans; D001936:Moraxella catarrhalis / Q000187:drug effects*; D016870:Neisseriaceae Infections / Q000382:microbiology; D010957:Plasmids; D013753:Tetracycline Resistance / Q000235:genetics
D004269:DNA, Bacterial