[The inhibition of keratoplasty rejection with topical cyclosporin A].
23 postoperative patients of keratoplasty were instilled 1% cyclosporin A eyedrops in addition to routine systemic corticosteroids, with reduced rate of rejection and increased rate of transparency of the corneal grafts. The values of OKT3, OKT4/OKT8 ratio, and Et-RFC were also reduced in comparison with those of the controls, indicating that the cyclosporin A eyedrops were effective in inhibiting corneal rejection.
Jai
H
H
Department of Ophthalmology, Third Teaching Hospital, Bethune University of Medical Sciences, Changchun.
Zhang
R X
RX
D000293:Adolescent; D000328:Adult; D016516:CD4-CD8 Ratio; D002648:Child; D016572:Cyclosporine / Q000008:administration & dosage / Q000627:therapeutic use*; D006084:Graft Rejection / Q000187:drug effects*; D006801:Humans; D015948:Keratoplasty, Penetrating / Q000276:immunology*; D008875:Middle Aged; D009883:Ophthalmic Solutions
D009883:Ophthalmic Solutions; D016572:Cyclosporine