title: Synthesis and study of antiprotozoal activity of some 5-nitrothiophene aldimines.
abstract: This paper reports on the synthesis and the antiparasitical activity of some 5-nitrothiophene aldimines variously substituted on aniline nucleus. The influence of substituents on the activity of the prepared compounds is discussed.
authors.affiliation: Laboratoire de Parasitologie, Faculté de Pharmacie de Merseille, France.
authors.forename: F
authors.initials: F
authors.lastname: Tedlaouti
authors.forename: M
authors.initials: M
authors.lastname: Gasquet
authors.forename: F
authors.initials: F
authors.lastname: Delmas
authors.forename: B
authors.initials: B
authors.lastname: Majester
authors.forename: P
authors.initials: P
authors.lastname: Timon-David
authors.forename: N
authors.initials: N
authors.lastname: Madadi
authors.forename: P
authors.initials: P
authors.lastname: Vanelle
authors.forename: J
authors.initials: J
authors.lastname: Maldonado
mesh_terms: D000818:Animals; D000981:Antiprotozoal Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D004748:Entamoeba histolytica / Q000187:drug effects; D056890:Eukaryota / Q000187:drug effects; D007097:Imines / Q000138:chemical synthesis* / Q000494:pharmacology; D007891:Leishmania / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010963:Plasmodium falciparum / Q000187:drug effects; D013329:Structure-Activity Relationship; D013876:Thiophenes / Q000138:chemical synthesis* / Q000494:pharmacology; D014246:Trichomonas vaginalis / Q000187:drug effects
chemical_list: D000981:Antiprotozoal Agents; D007097:Imines; D013876:Thiophenes