title: Molecular modelling studies and the chromatographic behaviour of oxiracetam and some closely related molecules.
abstract: Modelling studies have been carried out on the cellulose-based chiral stationary phase used to separate the enantiomers of three simple lactams. These studies have helped in understanding differences in the chromatographic behaviour of these molecules.
authors.affiliation: SmithKline Beecham Ltd., Welwyn, Herts, U.K.
authors.forename: P
authors.initials: P
authors.lastname: Camilleri
authors.forename: J A
authors.initials: JA
authors.lastname: Murphy
authors.forename: M R
authors.initials: MR
authors.lastname: Saunders
authors.forename: C J
authors.initials: CJ
authors.lastname: Thorpe
mesh_terms: D002240:Carbohydrate Sequence; D002482:Cellulose / Q000031:analogs & derivatives / Q000737:chemistry; D002845:Chromatography; D003199:Computer Systems; D008958:Models, Molecular; D008969:Molecular Sequence Data; D015394:Molecular Structure; D011619:Psychotropic Drugs / Q000737:chemistry / Q000302:isolation & purification; D011759:Pyrrolidines / Q000737:chemistry* / Q000302:isolation & purification*; D013237:Stereoisomerism
chemical_list: D011619:Psychotropic Drugs; D011759:Pyrrolidines; D002482:Cellulose; C040619:oxiracetam