[Primary biliary cirrhosis and pregnancy. Apropos of a clinical case. Review of the literature].
The appearance of pruritus and abnormal liver function tests (cellular damage) during pregnancy should of course suggest the diagnosis of intrahepatic cholestasis of pregnancy. However, these signs must also be recognized as signs of other hepatic diseases, especially primary biliary cirrhosis. The diagnosis is based on the search for antimitochondrial antibodies. This mode of presentation must not be overlooked because of major therapeutic consequences. The disease course often stabilizes with ursodeoxycholic acid, if administrated early.
Marpeau
L
L
Service de Gynécologie-Obstétrique, Hôpital Saint-Antoine, Paris.
Benifla
J L
JL
Chazoullière
O
O
Larue
L
L
Pigné
A
A
Poupon
R
R
Barrat
J
J
D000328:Adult; D002780:Cholestasis, Intrahepatic / Q000175:diagnosis; D005260:Female; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000175:diagnosis; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis
Cirrhose biliaire primitive (CBP) et grossesse. A propos d'un cas clinique. Revue de la littérature.