title: Changes in plasma levels of lipid peroxide and vitamin E during pregnancy.
abstract: The present study was undertaken in order to determine the changes in blood levels of lipid peroxide and vitamin E during pregnancy. 1. The man plasma level of lipid peroxide was 0.89 +/- 0.13 nmole/ml for non-pregnant women, while in pregnant women it was increased as the progressed pregnancy reaching 2.71 +/- 0.29 nmole/ml at full term. 2. The mean plasma, red cell and platelet levels of vitamin E were 6.6 +/- 0.9 micrograms/ml, 3.55 +/- 0.38 micrograms/ml packed cell and 99 +/- 25 micrograms/g protein for non-pregnant women, while in pregnant women the levels changed as the progressed pregnancy becoming 15.5 +/- 0.9 micrograms/ml, 2.43 +/- 0.24 micrograms/ml packed cell, and 244 +/- 19 micrograms/g protein at full term. It was shown in this study that during pregnancy the plasma level of lipid peroxide increased while the levels of vitamin E which inhibited the formation of lipid peroxide, increased in plasma and platelets, but decreased in red cells.
authors.affiliation: Department of Obstetrics and Gynaecology, Nara Medical University, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Iioka
authors.forename: S
authors.initials: S
authors.lastname: Akada
authors.forename: H
authors.initials: H
authors.lastname: Hisanaga
authors.forename: T
authors.initials: T
authors.lastname: Shimamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Yamada
authors.forename: I S
authors.initials: IS
authors.lastname: Moriyama
authors.forename: M
authors.initials: M
authors.lastname: Ichijo
mesh_terms: D000328:Adult; D001792:Blood Platelets / Q000378:metabolism; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D006801:Humans; D008054:Lipid Peroxides / Q000097:blood*; D011247:Pregnancy / Q000097:blood*; D014810:Vitamin E / Q000097:blood*
chemical_list: D008054:Lipid Peroxides; D014810:Vitamin E