title: Agranulocytosis--periodontal manifestations and treatment of the acute phase: a case report.
abstract: A case report of oral and periodontal manifestation of agranulocytosis in a 12-year-old girl is presented. The agranulocytic state may have been caused by chronic brucellosis since childhood. On admission to the hospital, the acute oral symptoms were treated in order to enable the child to eat and perform standard oral hygiene measures. Chlorhexidine gluconate 0.2% was irrigated daily under pressure for supra- and subgingival plaque control. Resolution of inflammation was achieved without increase in white blood count and thus can be attributed to the control of the local etiologic factor, i.e., plaque.
authors.affiliation: Department of Periodontics, The University of Texas Health Science Center at San Antonio.
authors.forename: Y
authors.initials: Y
authors.lastname: Zubery
authors.forename: O
authors.initials: O
authors.lastname: Moses
authors.forename: A
authors.initials: A
authors.lastname: Kozlovsky
mesh_terms: D000380:Agranulocytosis / Q000150:complications* / Q000209:etiology / Q000473:pathology; D002006:Brucellosis / Q000150:complications; D002443:Ceftriaxone / Q000627:therapeutic use; D002648:Child; D002710:Chlorhexidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003773:Dental Plaque / Q000150:complications; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D009910:Oral Hygiene; D010510:Periodontal Diseases / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology
chemical_list: D005839:Gentamicins; D002443:Ceftriaxone; C010882:chlorhexidine gluconate; D002710:Chlorhexidine