title: [Treatment of neurotoxoplasmosis with the combination sulfamethoxazole-trimethoprim: report of 10 cases].
abstract: Toxoplasmosis is the most frequent parasitic infection of the CNS in the immunocompromised host. When promptly treated with the sulfadiazine-pyrimethamine combination patients with cerebral toxoplasmosis characteristically respond with clear clinical and CT improvement within 1-2 weeks. We report the results achieved with the combination sulfamethoxazole-trimethoprim, and conclude that both combinations have similar effects in the treatment of CNS toxoplasmosis.
authors.affiliation: Divisão de Clínica Neurológica, Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, Brasil.
authors.forename: J P
authors.initials: JP
authors.lastname: Nóbrega
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000328:Adult; D002493:Central Nervous System Diseases / Q000150:complications / Q000188:drug therapy* / Q000469:parasitology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009894:Opportunistic Infections / Q000150:complications; D011379:Prognosis; D014123:Toxoplasmosis / Q000150:complications / Q000188:drug therapy*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use*
chemical_list: D015662:Trimethoprim, Sulfamethoxazole Drug Combination
vernacular_title: Tratamento da neurotoxoplasmose com a associação sulfametoxazol-trimetoprim. Relato de 10 casos.