Analysis of chromosome band 1p36 alterations by chromosomal in situ suppression hybridization with a microclone DNA bank.
Alterations of the distal portion of chromosome Ip are a recurrent abnormality of several types of human cancer. In this study we show that chromosomal in situ suppression hybridization with a regional 1p36 DNA bank generated by microdissection and microcloning can be employed to detect translocations involving 1p36.
Zink
D
D
Institut für Experimentelle Pathologie, Deutsches Krebsforschungszentrum, Heidelberg, Federal Republic of Germany.
Weith
A
A
Martinsson
T
T
Schwab
M
M
D002460:Cell Line; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D025063:Chromosome Disorders; D002878:Chromosomes, Human, Pair 1; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics*; D004273:DNA, Neoplasm / Q000235:genetics*; D016208:Databases, Factual; D006801:Humans; D008214:Lymphocytes; D009369:Neoplasms / Q000235:genetics*; D009447:Neuroblastoma / Q000235:genetics
D004273:DNA, Neoplasm; D004247:DNA