[The antiradical activity of coumarin reductones].
The antiradical activity of coumarine reductones was investigated by the method of inhibition of Fe2+ induced chemiluminescence of egg-yolk lipoproteins. All coumarines studied exhibited high antioxidant activity. The dependence of chemiluminescence intensity on the antioxidant concentration shows that coumarines reductions resemble their chemical analog--ascorbic acid rather than the lipid antioxidant butilated hydroxitoluene (ionol).
Vladimirov
Iu A
IuA
Parfenov
E A
EA
Epanchintseva
O M
OM
Smirnov
L D
LD
D001205:Ascorbic Acid / Q000494:pharmacology; D002084:Butylated Hydroxytoluene / Q000494:pharmacology; D003374:Coumarins / Q000494:pharmacology*; D003864:Depression, Chemical; D004305:Dose-Response Relationship, Drug; D004527:Egg Proteins / Q000187:drug effects / Q000378:metabolism; D005609:Free Radicals; D015227:Lipid Peroxidation / Q000187:drug effects; D008074:Lipoproteins / Q000187:drug effects / Q000378:metabolism; D008163:Luminescent Measurements; D008315:Malondialdehyde / Q000031:analogs & derivatives* / Q000494:pharmacology; D013329:Structure-Activity Relationship
D003374:Coumarins; D004527:Egg Proteins; D005609:Free Radicals; D008074:Lipoproteins; D002084:Butylated Hydroxytoluene; C010778:reductone; D008315:Malondialdehyde; D001205:Ascorbic Acid
Antiradikal'naia aktivnost' kumarinovykh reduktonov.