[Intensification of lipid peroxidation upon damage to cell membranes].
It is shown that during sensitized by haematoporphyrin photooxidation accumulation of TBA-active products in destroyed cells (human erythrocytes, rat thymocytes, pig leucocytes) occurs considerably faster than in the intact ones. Similar acceleration is observed in intact erythrocytes after the amount of reduced glutathione in it was decreased. It is supposed that the cause of intensification processes of lipid peroxidation consists in separation of the antioxidant system from the plasma membrane.
Chernitskiĭ
E A
EA
Bolodon
V N
VN
Vorobeĭ
A V
AV
D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D004912:Erythrocytes / Q000378:metabolism; D006461:Hemolysis; D006801:Humans; D007962:Leukocytes / Q000378:metabolism; D015227:Lipid Peroxidation; D008563:Membrane Lipids / Q000378:metabolism*; D051381:Rats; D013552:Swine; D013858:Thiobarbiturates / Q000378:metabolism; D013950:Thymus Gland / Q000166:cytology / Q000378:metabolism
D008563:Membrane Lipids; D013858:Thiobarbiturates; C029684:thiobarbituric acid
Intensifikatsiia perekisnogo okisleniia lipidov pri povrezhdenii membran kletok.