title: Ocular cicatricial pemphigoid.
abstract: Cicatricial pemphigoid is an inflammatory disease of presumed autoimmune etiology. It most commonly affects the conjunctiva and oral mucosa and less commonly the skin. The ocular manifestations of the disease include bilateral conjunctival shrinkage, xerosis, and corneal opacification. The progression of cicatricial pemphigoid is variable and can be interrupted by periods of remission or by periods of rapid exacerbation. Ocular surgery and topical pharmaceuticals may contribute to the exacerbation of this disease. Current treatment consists of systemic immunosuppressants and systemic corticosteroids.
authors.affiliation: V.A. Medical Center, Battle Creek, MI 49016.
authors.forename: M R
authors.initials: MR
authors.lastname: Vandeveer
mesh_terms: D001327:Autoimmune Diseases / Q000175:diagnosis; D003229:Conjunctival Diseases / Q000175:diagnosis* / Q000188:drug therapy; D003316:Corneal Diseases / Q000175:diagnosis* / Q000188:drug therapy; D005141:Eyelid Diseases / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010390:Pemphigoid, Benign Mucous Membrane / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D007166:Immunosuppressive Agents