title: Coexistence of acetylcholine and calcitonin gene-related peptide in the vestibular efferent neurons in the rat.
abstract: An immunocytochemical study combined with the retrograde tracer technique was performed in the rat to assess the vestibular efferent system. All 3 neuron groups which give rise to axons terminating on the vestibular end-organs were cholinergic, i.e., a group dorsolateral to the genu of the facial nerve (DL), a group dorsomedial to this genu (M), and scattered cells in the parvocellular reticular nucleus (PCRt). In addition, we further demonstrated that about 55% of the cholinergic cells in DL had calcitonin gene-related peptide.
authors.affiliation: Department of Otolaryngology, Osaka University Medical School, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ohno
authors.forename: N
authors.initials: N
authors.lastname: Takeda
authors.forename: M
authors.initials: M
authors.lastname: Yamano
authors.forename: T
authors.initials: T
authors.lastname: Matsunaga
authors.forename: M
authors.initials: M
authors.lastname: Tohyama
mesh_terms: D000109:Acetylcholine / Q000032:analysis*; D000818:Animals; D001369:Axons / Q000648:ultrastructure; D015740:Calcitonin Gene-Related Peptide / Q000032:analysis*; D002795:Choline O-Acetyltransferase / Q000032:analysis*; D004525:Efferent Pathways / Q000166:cytology* / Q000201:enzymology; D007106:Immune Sera; D007150:Immunohistochemistry; D008297:Male; D009474:Neurons / Q000166:cytology* / Q000201:enzymology; D051381:Rats; D011919:Rats, Inbred Strains; D014726:Vestibular Nuclei / Q000166:cytology* / Q000201:enzymology
chemical_list: D007106:Immune Sera; D002795:Choline O-Acetyltransferase; D015740:Calcitonin Gene-Related Peptide; D000109:Acetylcholine