[The immunogenicity of mono- and associated vaccines made from strains of opportunistic bacteria].
In experiments on white mice the immunogenic potency of two variants of combined vaccines prepared from strains of opportunistic bacteria was compared with that of monovaccines used as the components of the combined vaccines. All the vaccines under study were found highly immunogenic. Decrease of monovaccine share in the combined vaccine did not reduce the immunogenic potency to any of the strains. An 8- to 16-fold increase in the level of specific antibodies in the colostric lactosera of cows immunized with combined vaccines was observed, and the survival rate of newborn calves increased 3- to 4-fold.
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D000818:Animals; D001428:Bacterial Vaccines / Q000276:immunology*; D002417:Cattle; D004306:Dose-Response Relationship, Immunologic; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D004926:Escherichia coli / Q000276:immunology; D005260:Female; D007114:Immunization; D051379:Mice; D011513:Proteus mirabilis / Q000276:immunology; D011514:Proteus vulgaris / Q000276:immunology; D011550:Pseudomonas aeruginosa / Q000276:immunology; D012486:Salmonella typhimurium / Q000276:immunology; D015164:Vaccines, Inactivated / Q000276:immunology
D001428:Bacterial Vaccines; D004338:Drug Combinations; D015164:Vaccines, Inactivated
Izuchenie immunogennosti mono- i assotsiirovannykh vaktsin iz shtammov uslovno-patogennykh bakteriĭ.