Efficacy of aqueous and butanolic fractions of Albizzia anthelmintica against experimental Hymenolepis diminuta infestation in rats.
The oral administration of the aqueous fraction of Albizzia anthelmintica bark extract in a concentration range of 50-150 g/kg body weight was safe and infestation with Hymenolepis diminuta was completely eliminated. The butanolic fraction of A anthelmintica bark extract given by stomach tube in concentrations ranging from 25-150 g/kg was highly toxic to rats and was inactive against H diminuta.
Galal
M
M
Medical and Aromatic Herbs Research Institute, National Council for Research, Sudan.
Bashir
A K
AK
Salih
A M
AM
Adam
S E
SE
D020001:1-Butanol; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D000440:Butanols; D005260:Female; D006925:Hymenolepiasis / Q000150:complications / Q000188:drug therapy* / Q000401:mortality; D007411:Intestinal Diseases, Parasitic / Q000150:complications / Q000188:drug therapy; D008297:Male; D010936:Plant Extracts / Q000627:therapeutic use*; D010946:Plants, Medicinal / Q000737:chemistry*; D011180:Postmortem Changes; D051381:Rats
D000871:Anthelmintics; D000440:Butanols; D010936:Plant Extracts; D020001:1-Butanol