title: Synthesis and antiaggregatory activity of antiflammin related peptides.
abstract: The peptide H-Lys-Val-Leu-Asp-OH (KVLD), derived from antiflammins, and its analog H-Lys-Val-Asp-Leu-OH (KVDL) were prepared by solution synthesis. KVLD does not inhibit platelet aggregation in contrast to the results recently published.
authors.affiliation: Dipartimento Scienze Farmaceutiche Università di Ferrara, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Marastoni
authors.forename: V
authors.initials: V
authors.lastname: Scaranari
authors.forename: S
authors.initials: S
authors.lastname: Salvadori
authors.forename: R
authors.initials: R
authors.lastname: Tomatis
authors.forename: S
authors.initials: S
authors.lastname: Spisani
authors.forename: S
authors.initials: S
authors.lastname: Traniello
mesh_terms: D000595:Amino Acid Sequence; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D005340:Fibrinogen / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000138:chemical synthesis* / Q000494:pharmacology; D010975:Platelet Aggregation Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D009842:Oligopeptides; D010975:Platelet Aggregation Inhibitors; C074440:lysyl-valyl-leucyl-aspartic acid; C074441:lysyl-valyl-aspartyl-leucine; D005340:Fibrinogen