Intestinal metaplasia of the gastric mucosa: a study of its incidence in various disease states.
The incidence of intestinal metaplasia (IM) was studied in 159 specimens from gastric mucosa. Rare in histologically normal specimens (4%), the IM showed the highest incidence in patients with gastric carcinoma (75%). Intermediate values were observed in chronic atrophic gastritis (25%) and peptic ulcer (21%). Histochemical data shows that type complete-IM was most common in benign conditions; type incomplete-IM and particularly subtype secreting sulphomucins revealed a higher frequence in the mucosa bordering carcinomas.
Sirigu
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Institute of Internal Medicine, University of Cagliari, Italy.
Dessì
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Tocco
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Usai
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D000328:Adult; D000368:Aged; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology*; D005757:Gastritis, Atrophic / Q000473:pathology; D006801:Humans; D008297:Male; D008679:Metaplasia / Q000473:pathology; D008875:Middle Aged; D010437:Peptic Ulcer / Q000473:pathology; D013274:Stomach Neoplasms / Q000473:pathology