title: Development of novel oestrogen-receptor antagonists.
authors.affiliation: Research I, ICI Pharmaceuticals, Macclesfield, Cheshire, U.K.
authors.forename: A E
authors.initials: AE
authors.lastname: Wakeling
authors.forename: J
authors.initials: J
authors.lastname: Bowler
mesh_terms: D000818:Animals; D001943:Breast Neoplasms / Q000188:drug therapy; D015195:Drug Design; D004958:Estradiol / Q000031:analogs & derivatives / Q000737:chemistry / Q000494:pharmacology; D004965:Estrogen Antagonists / Q000737:chemistry / Q000494:pharmacology; D005260:Female; D000077267:Fulvestrant; D006801:Humans; D009376:Neoplasms, Hormone-Dependent / Q000188:drug therapy; D053284:Polyunsaturated Alkamides; D011960:Receptors, Estrogen / Q000037:antagonists & inhibitors*; D013629:Tamoxifen / Q000494:pharmacology
chemical_list: D004965:Estrogen Antagonists; D053284:Polyunsaturated Alkamides; D011960:Receptors, Estrogen; D013629:Tamoxifen; D000077267:Fulvestrant; D004958:Estradiol; C051781:ICI 164384