[Multiple malignant tumors in Recklinghausen's neurofibromatosis].
The case of a woman aged 77 years, with cutaneous manifestations of neurofibromatosis, is described, in whom cutaneous fibromas with malignant degeneration, displaying an aspect of fibrosarcoma, were detected. The anatomopathological examination shows fibroblastic type tumoral cells, of a globulous aspect, as well as the presence of cell monstruosities with numerous mitoses, among nervous cells and amyelinic fibers are found. Malignization occurs in Recklinghausen's neurofibromatosis at a rate up to 20% of cases.
Crăiţoiu
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Clinica Oftalmologică, Craiova.
Enculescu
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D000368:Aged; D005142:Eyelid Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005143:Eyelids / Q000473:pathology; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D009456:Neurofibromatosis 1 / Q000175:diagnosis* / Q000473:pathology; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology
Malignizări multiple în neurofibromatoza Recklinghausen.