[The correlation between the clinical stage and multimodal treatment in breast cancer expressed in the 5-year survival rate].
The survival rate in 143 patients with breast cancer followed up for 60 months has been evaluated by the regression Cox method and life table method, a number of representative variables for tumor and/or host being taken into account. The Cox model coefficients pointed out the following factors to positively influence the survival: age, premenopausal status, surgery, radiotherapy and complete chemotherapy (6-12 cycles). Negative and highly negative values recorded within variables: tumor over 5 cm, the presence of metastases, Karnofsky index less than 80 and the postmenopausal status generally correlated with the disease in advanced clinical stages. An apparently better survival in patients who underwent radiotherapy as compared to those who underwent an associated radiochemotherapy could be the result of the preferential associated treatment in advanced stages. The optimal intensity of chemotherapy positively influences the survival, except in late stages, suggesting the necessity of chemotherapy in initial stages.
Carasevici
E
E
Clinica oncologie-radiologie, Spitalul universitar Sf. Spiridon, Iaşi.
Miron
L
L
Cianga
C
C
D000367:Age Factors; D001943:Breast Neoplasms / Q000401:mortality* / Q000473:pathology / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D011379:Prognosis; D012044:Regression Analysis; D012383:Romania; D015996:Survival Rate
Corelaţia dintre stadiul clinic şi tratamentul multimodal în cancerul mamar, exprimată în rata de supravieţuire la 5 ani.