[Code of codon roots, determining the intra- and intermolecular interaction of amino acids in peptide chains].
To study the recognition processes and interaction of peptides and proteins, a model has been suggested according to which the first steps of complex formation of molecules are defined by G/C and A/U complementarity of codon roots of amino acid forming the molecules contact sites or surfaces. In contrast to amino acid--antiamino acid interaction code (L. B. Mekler, 1969), the code of codon roots involves the interaction of amino acids independently of the base structures in nucleotide triplets in positions 1 and 3. The analysis of the spectra of point mutations homologous proteins confirms the possible role of the root code.
Chipens
G I
GI
Ievinia
N G
NG
Rudzish
R B
RB
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000737:chemistry*; D003062:Codon; D008969:Molecular Sequence Data; D009154:Mutation; D010455:Peptides / Q000737:chemistry*
D000596:Amino Acids; D003062:Codon; D010455:Peptides
Kod korneĭ kodonov, opredeliaiushchiĭ vnutri- i mezhmolekuliarnoe vzaimodeĭstvie aminokislot v peptidnykh tsepiakh.