Agenesis of the corpus callosum. Its associated anomalies and syndromes with special reference to the Apert syndrome.
Agenesis of the corpus callosum may be associated with a variety of central nervous system (CNS) and non-CNS abnormalities and is known to occur in a number of specific syndromes. It can be a marker for several inherited metabolic disorders. Study of the Apert syndrome shows a recurrent pattern of CNS abnormalities, including defects of the corpus callosum and limbic structures, megalencephaly, misshapen brain, distortion ventriculomegaly, and gyral anomalies.
Cohen
M M
MM
Faculty of Dentistry, Dalhousie University, Halifax, Nova Scotia, Canada.
Kreiborg
S
S
D000168:Acrocephalosyndactylia / Q000473:pathology*; D000328:Adult; D061085:Agenesis of Corpus Callosum; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D013577:Syndrome