title: Use of Z-amino acid-glyceryl esters in protease catalyzed peptide synthesis.
abstract: The alpha-glyceryl esters of Z-Gly, Z-Phe and Z-Tyr were synthesized and their use for protease catalyzed peptide synthesis was studied. Three enzymes isolated from crude papain were compared in their catalytic potency. Syntheses with alpha-chymotrypsin were performed in a biphasic system.
authors.affiliation: Deutsches Wollforschungsinstitut, Aachen, BRD.
authors.forename: J
authors.initials: J
authors.lastname: Wiese
authors.forename: H G
authors.initials: HG
authors.lastname: Gattner
authors.forename: H
authors.initials: H
authors.lastname: Zahn
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000737:chemistry; D004151:Dipeptides / Q000138:chemical synthesis / Q000737:chemistry; D010450:Endopeptidases / Q000737:chemistry*; D004952:Esters / Q000138:chemical synthesis / Q000737:chemistry; D005990:Glycerol / Q000737:chemistry; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry; D010649:Phenylalanine / Q000031:analogs & derivatives / Q000737:chemistry
chemical_list: D000596:Amino Acids; D004151:Dipeptides; D004952:Esters; D010455:Peptides; C017105:carbobenzoxyphenylalanine; D010649:Phenylalanine; D010450:Endopeptidases; D005990:Glycerol