title: Chromosome structure and eukaryotic gene organization.
abstract: The DNA in the eukaryotic nucleus is highly compacted but well organized into distinct regional units. Chromosomal bands are characterized by their structure and distinctive replication time. They are subdivided into chromatin loops which serve as functional domains that have discrete boundary elements and can be regulated during development.
authors.affiliation: Department of Cellular Biochemistry, Hebrew University, Hadassah Medical School, Jerusalem, Israel.
authors.forename: D
authors.initials: D
authors.lastname: Kitsberg
authors.forename: S
authors.initials: S
authors.lastname: Selig
authors.forename: H
authors.initials: H
authors.lastname: Cedar
mesh_terms: D000818:Animals; D002645:Chickens / Q000235:genetics; D002843:Chromatin / Q000648:ultrastructure; D002875:Chromosomes / Q000648:ultrastructure*; D004247:DNA / Q000235:genetics; D004330:Drosophila / Q000235:genetics; D005786:Gene Expression Regulation; D008322:Mammals / Q000235:genetics; D012045:Regulatory Sequences, Nucleic Acid
chemical_list: D002843:Chromatin; D004247:DNA