title: [Biological evaluation of In-Ceram-ceramics compared to cobalt-base-alloys and the metals titanium, tantalum and niobium in animal experiments].
abstract: The aim of the study was to evaluate the biocompatibility of the in-cream-ceramic-system in several technological phases by animal experiments. The comparative materials were the Co-Cr-alloys Remanium CD and Wirobond and the implant materials Titanium, Tantalum and Columbium and the high biocompatible material Teflon. The experiments were carried out in accordance with the DIN-standard 13,930 using subcutaneous implantation to verify the toxicity of the materials. 20 cylindrical test pieces were implanted into the subcutaneous connective tissue of the neck in rats. After 12 weeks the animals were sacrificed and the implants were removed with the surrounding tissues. The thickness of the fibrous capsule and the number of cells within the capsule were measured microscopically. The in-ceram-ceramic-system showed the same results like approved Co-Cr-alloys. The results of the implant materials were not attained.
authors.affiliation: Poliklinik für Zahnärztliche Prothetik, Medizinischen Akademie Erfurt.
authors.forename: F
authors.initials: F
authors.lastname: Limberger
authors.forename: E
authors.initials: E
authors.lastname: Lenz
mesh_terms: D000537:Aluminum Oxide / Q000633:toxicity*; D000818:Animals; D001672:Biocompatible Materials / Q000633:toxicity*; D002858:Chromium Alloys / Q000633:toxicity*; D003035:Cobalt / Q000633:toxicity; D003776:Dental Porcelain / Q000633:toxicity*; D005549:Foreign-Body Reaction / Q000209:etiology; D009556:Niobium / Q000633:toxicity; D011138:Polytetrafluoroethylene; D051381:Rats; D013635:Tantalum / Q000633:toxicity; D014025:Titanium / Q000633:toxicity
chemical_list: D001672:Biocompatible Materials; D002858:Chromium Alloys; D009556:Niobium; D003776:Dental Porcelain; C070870:In-Ceram; D003035:Cobalt; D013635:Tantalum; D011138:Polytetrafluoroethylene; D014025:Titanium; D000537:Aluminum Oxide
vernacular_title: Biologische Prüfung der In-Ceram-Keramik im Vergleich mit Kobaltbasis-Legierungen und den Metallen Titan, Tantal und Niob im Tierexperiment.