Anticoagulant effects of the selective factor XA inhibitors tick anticoagulant peptide and antistasin in the APTT assay are determined by the relative rate of prothrombinase inhibition.
Dunwiddie
C T
CT
Department of Pharmacology, Merck Sharp and Dohme Research Laboratories, West Point, PA 19486.
Smith
D E
DE
Nutt
E M
EM
Vlasuk
G P
GP
D000925:Anticoagulants / Q000494:pharmacology*; D060829:Arthropod Proteins; D065427:Factor Xa Inhibitors; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins; D007447:Invertebrate Hormones / Q000494:pharmacology*; D010314:Partial Thromboplastin Time; D010455:Peptides / Q000494:pharmacology*; D011994:Recombinant Proteins / Q000494:pharmacology; D013925:Thromboplastin / Q000037:antagonists & inhibitors*
D000925:Anticoagulants; D060829:Arthropod Proteins; D065427:Factor Xa Inhibitors; D036341:Intercellular Signaling Peptides and Proteins; D007447:Invertebrate Hormones; D010455:Peptides; D011994:Recombinant Proteins; C063967:tick anticoagulant peptide; C053155:antistasin; D013925:Thromboplastin