title: Psychosocial risk factors distinguishing melancholic and nonmelancholic depression: a comparison of six systems.
abstract: We examined six systems or scales designed to distinguish melancholia from residual nonmelancholic depressive disorders in a sample of 305 patients. A count of the number of significant psychosocial risk factors showed that a clinical diagnosis was the most differentiating (19 significant risk factors), followed by the Newcastle index (13), DSM-III (10), and the CORE system (10)--the last essentially assessing psychomotor change; Research Diagnostic Criteria (RDC) (7) and an endogeneity symptom scale (2) were the least differentiating. A subsample of "composite melancholics" was derived, comprising 138 who met "melancholia" criteria for DSM-III, RDC, and CORE, and they were contrasted with residual depressives. The composite melancholics were older, had had a briefer depressive episode, and differed significantly on 12 risk factors, essentially being less likely to report deprivational experiences such as deficient parenting and dysfunctional marital relationships. We suggest that such a risk factor strategy is of potential use in refining the clinical definition of melancholia.
authors.affiliation: School of Psychiatry, University of New South Wales, Randwick, Australia.
authors.forename: G
authors.initials: G
authors.lastname: Parker
authors.forename: D
authors.initials: D
authors.lastname: Hadzi-Pavlovic
authors.forename: P
authors.initials: P
authors.lastname: Mitchell
authors.forename: I
authors.initials: I
authors.lastname: Hickie
authors.forename: K
authors.initials: K
authors.lastname: Wilhelm
authors.forename: H
authors.initials: H
authors.lastname: Brodaty
authors.forename: P
authors.initials: P
authors.lastname: Boyce
authors.forename: K
authors.initials: K
authors.lastname: Roy
mesh_terms: D000223:Adaptation, Psychological; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001714:Bipolar Disorder / Q000145:classification / Q000175:diagnosis* / Q000523:psychology; D003866:Depressive Disorder / Q000145:classification / Q000175:diagnosis* / Q000523:psychology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008016:Life Change Events; D008297:Male; D008875:Middle Aged; D010553:Personality Development; D010555:Personality Inventory / Q000706:statistics & numerical data; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data*; D011594:Psychometrics; D012931:Social Environment; D012944:Social Support