[Effect of dopamine on cecum motility in sheep].
The influence of dopamine on the motility of the caecum were studied. The experiments were carried out on 4 sheep with chronic fistulas of the caecum. The contractions of the caecum were recorded by the balloon method. Dopamine infused intravenously at a rate 29-38 micrograms.kg-1.min-1 inhibited the motility of the caecum. Dopamine infused after beta-adrenergic blocker propranolol (0.5-1.0 mg.kg-1) inhibited the movements of the caecum, however administrated after domperidone (0.2-0.4 mg.kg-1) didn't change its movements. It has been concluded that dopamine inhibits the caecum motility in sheep through specific dopaminergic receptors.
Zieba
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Katedra Fizjologii Zwierzat Wydziału Medycyny Weterynaryjnej AR, Wrocławiu.
Wegrzyn
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Cebrat
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Leroch
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D000818:Animals; D002432:Cecum / Q000187:drug effects* / Q000502:physiology; D004294:Domperidone / Q000494:pharmacology; D004298:Dopamine / Q000494:pharmacology*; D004347:Drug Interactions; D005769:Gastrointestinal Motility / Q000187:drug effects*; D011433:Propranolol / Q000494:pharmacology; D011954:Receptors, Dopamine / Q000187:drug effects / Q000502:physiology; D012756:Sheep / Q000502:physiology*
D011954:Receptors, Dopamine; D004294:Domperidone; D011433:Propranolol; D004298:Dopamine
Wpływ dopaminy na motoryke jelita ślepego u owiec.