[Use of the principle of reverse problems for detecting processes, occurring in cells suspended in culture. I. Distribution in the exponential growth phase of the age component of the cell population by its dynamic characteristics].
A mathematical model of age distribution in the suspension culture was verified. This model used the principle of reverse problems and allowed determination of age distribution from the cell numbers dynamics in the population. The verification was based on the complex non-destructive measurement of the microorganism parameters, which allowed simultaneous determination of the cell population dynamics and the distribution of cells according to their projection areas. The experiments were carried out on E. coli culture.
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D003470:Culture Media; D004926:Escherichia coli / Q000254:growth & development*; D005285:Fermentation; D008962:Models, Theoretical
D003470:Culture Media
Primenenie printsipa obratnykh zadach dliia vyiavleniia protsessov, proiskhodiashchikh v kletkakh pri ikh suspenzionnom kul'tivirovanii. I. Opredelenie v éksponentsial'noĭ faze rosta vozrastnogo sostava kletochnoĭ populiatsii po ee dinamicheskim kharakteristikam.