title: Increased endothelial cell stimulating angiogenesis factor in patients with tibial fractures.
abstract: Angiogenesis is an important step in the normal process of fracture healing, irrespective of the method of fixation. Using a quantitative assay, the amount of endothelial cell stimulating factor (ESAF) has been determined in a small group of patients with tibial fractures. ESAF levels were found to be increased when compared with normal volunteers, although this increase was relatively less in fractures held with intramedullary nails than with external fixation.
authors.affiliation: Royal Infirmary of Edinburgh, UK.
authors.forename: A L
authors.initials: AL
authors.lastname: Wallace
authors.forename: B
authors.initials: B
authors.lastname: McLaughlin
authors.forename: J B
authors.initials: JB
authors.lastname: Weiss
authors.forename: S P
authors.initials: SP
authors.lastname: Hughes
mesh_terms: D000328:Adult; D043925:Angiogenesis Inducing Agents / Q000097:blood*; D005592:Fracture Fixation; D005594:Fracture Fixation, Intramedullary; D006801:Humans; D008297:Male; D013977:Tibia / Q000098:blood supply; D013978:Tibial Fractures / Q000097:blood* / Q000601:surgery; D014945:Wound Healing / Q000502:physiology
chemical_list: D043925:Angiogenesis Inducing Agents