HIV infection of the adult thymus: an even more conventional theory explaining CD4 cell decrease and CD8 cell increase in AIDS.
CD4 cells are known to drop and CD8 cells are known to increase in patients with HIV infection. It is accepted that this is the result of HIV selectively killing CD4 cells; we propose an alternative explanation for this phenomenon.
Harris
P J
PJ
AIDS Clinical Research Center, Washington, DC 20009.
Candeloro
P D
PD
Bunn
J E
JE
D000328:Adult; D016516:CD4-CD8 Ratio; D015658:HIV Infections / Q000209:etiology*; D006801:Humans; D008954:Models, Biological; D016176:T-Lymphocyte Subsets / Q000473:pathology; D013950:Thymus Gland / Q000473:pathology