Transthyretin amyloidoses of familial amyloidotic polyneuropathy as a paradigm for the genetic control of spontaneous generation of infectious amyloids by patterned configurational change in host precursors in Creutzfeldt-Jacob disease.
Transthyretin amyloidosis. Infectious amyloid proteins. Unconventional slow virus diseases. Spongiform encephalopathies. Genetic control and point mutations.
Gajdusek
D C
DC
National Institutes of Health, Bethesda, Maryland.
D000686:Amyloidosis / Q000235:genetics*; D000818:Animals; D007562:Creutzfeldt-Jakob Syndrome / Q000235:genetics*; D006801:Humans; D009154:Mutation; D009422:Nervous System Diseases / Q000235:genetics*