title: The effect of prolonged administration of ketotifen on skin reactions.
abstract: 27 patients suffering from respiratory Allergies (asthma and/or rhinitis) were studied. They were given 25 micrograms of ketotifen/k/every 12 hours for a period of 6 months intradermal tests with house dust and Skin prick tests with D. pteronissinus, D. farinae and 7 grass mix were carried out at the start of the study, and at 3 and 6 months, at which times no significant reduction in induration and erythema was observed.
authors.affiliation: Unit of Allergy and Immunology, Hospital Infantil Universitario Lorencita Villegas de Santos, Bogotá, Colombia.
authors.forename: F J
authors.initials: FJ
authors.lastname: Leal
mesh_terms: D000485:Allergens; D000941:Antigens; D039741:Antigens, Dermatophagoides; D001249:Asthma / Q000188:drug therapy / Q000276:immunology; D002648:Child; D004391:Dust; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects*; D007428:Intradermal Tests; D007665:Ketotifen / Q000494:pharmacology*; D008297:Male; D008407:Mast Cells / Q000187:drug effects; D011058:Pollen; D012220:Rhinitis / Q000188:drug therapy / Q000276:immunology
chemical_list: D000485:Allergens; D000941:Antigens; D039741:Antigens, Dermatophagoides; D004391:Dust; D007665:Ketotifen