title: The three-dimensional x-ray crystal structure of HIV-1 protease complexed with a hydroxyethylene inhibitor.
authors.affiliation: Roche Research Center, Hoffmann-La Roche Inc., Nutley, New Jersey 07110.
authors.forename: B J
authors.initials: BJ
authors.lastname: Graves
authors.forename: M H
authors.initials: MH
authors.lastname: Hatada
authors.forename: J K
authors.initials: JK
authors.lastname: Miller
authors.forename: M C
authors.initials: MC
authors.lastname: Graves
authors.forename: S
authors.initials: S
authors.lastname: Roy
authors.forename: C M
authors.initials: CM
authors.lastname: Cook
authors.forename: A
authors.initials: A
authors.lastname: Kröhn
authors.forename: J A
authors.initials: JA
authors.lastname: Martin
authors.forename: N A
authors.initials: NA
authors.lastname: Roberts
mesh_terms: D001665:Binding Sites; D016333:HIV Protease / Q000737:chemistry*; D017320:HIV Protease Inhibitors; D006860:Hydrogen Bonding; D015394:Molecular Structure; D009842:Oligopeptides / Q000737:chemistry / Q000494:pharmacology; D011480:Protease Inhibitors / Q000737:chemistry / Q000494:pharmacology; D011487:Protein Conformation; D014961:X-Ray Diffraction
chemical_list: D017320:HIV Protease Inhibitors; D009842:Oligopeptides; D011480:Protease Inhibitors; C074409:Ro 31-8588; D016333:HIV Protease