title: [Blood system responses in inflammation and mechanisms of their development].
abstract: A model of acute infectious peritonitis in mice demonstrated that the inflammation is attended by marked biphasic activation of bone-marrow granulomonocytopoiesis and that the activation is due in many respects to increased functional activity of elements forming the hemopoiesis-inducing microenvironment. This was suggested by increased colony-stimulating activity of the marrow mononuclear cells and the content of hemopoietic islets in the marrow. The colony-stimulating activity of peripheral blood also increased. It was established that inflammation is also characterized by activation of bone-marrow erythropoiesis, which is linked with increased erythropoietic activity of the hemopoiesis-inducing microenvironment and blood. There was a relation between the hemopoietic changes and the kinetics of leukocytes in the focus of inflammation.
authors.forename: A M
authors.initials: AM
authors.lastname: Dygaĭ
authors.forename: N A
authors.initials: NA
authors.lastname: Klimenko
authors.forename: E V
authors.initials: EV
authors.lastname: Abramova
authors.forename: V P
authors.initials: VP
authors.lastname: Khakhov
authors.forename: I V
authors.initials: IV
authors.lastname: Bogdashin
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Zakharova
authors.forename: E V
authors.initials: EV
authors.lastname: Simanina
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Sherstoboev
authors.forename: B Iu
authors.initials: BIu
authors.lastname: Gumilevskiĭ
authors.forename: D A
authors.initials: DA
authors.lastname: Boldyshev
mesh_terms: D000818:Animals; D006410:Hematopoiesis / Q000276:immunology*; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D010538:Peritonitis / Q000097:blood / Q000276:immunology*
vernacular_title: Reaktsii sistemy krovi pri vospalenii i mekhanizmy ikh razvitiia.