title: Aortocoronary vascular prosthesis made of siliconized homologous vein or bovine sacral artery.
abstract: The purpose of our study was to develop and prepare aortocoronary prostheses, test them experimentally in multivascular and coronary reoperations in case of missing autologous grafts and to use them for shunt operations in cardiac surgery. Human vein or bovine sacral artery were used for preparing aortocoronary prostheses. As for metrics of 9-14 Charr. and a length of 20-30 cm were obtained. Aortocoronary prostheses were preformed according to the coronary configuration for left descending artery, circumflex artery and right coronary artery. Aortocoronary prostheses meet the conditions of desantigenicity, sterility, athrombogenicity, tightness and high tensile strength, tear propagation strength, bursting pressure and shrinkage temperature. Experimental testing was performed in dogs in aortofemoral and aortocoronary positions. Infections did not occur. The healing process and structural changes of aortocoronary vascular prostheses (grafts) were examined histologically and evaluated by means of scanning electron microscopic examinations. Athrombogenicity and healing-in without inflammation and calcification were proved.
authors.affiliation: Clinic and Policlinic of Cardiac Surgery, Humboldt University, Charité, Berlin, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Kruse
authors.forename: J
authors.initials: J
authors.lastname: Borsow
authors.forename: P
authors.initials: P
authors.lastname: Buntrock
authors.forename: G
authors.initials: G
authors.lastname: Matthes
authors.forename: H
authors.initials: H
authors.lastname: Warnke
authors.forename: M
authors.initials: M
authors.lastname: Wenzel
mesh_terms: D000818:Animals; D001158:Arteries; D001705:Bioprosthesis; D001807:Blood Vessel Prosthesis; D002417:Cattle; D001026:Coronary Artery Bypass; D003331:Coronary Vessels / Q000601:surgery; D004285:Dogs; D005500:Follow-Up Studies; D006801:Humans; D012828:Silicones; D013718:Tensile Strength; D013997:Time Factors; D014680:Veins
chemical_list: D012828:Silicones