Long-term survival of a patient with prosthetic valve endocarditis due to Trichosporon beigelii.
A case is described of a 49-year-old man with rheumatic aortic valve disease who developed endocarditis seven years after valvular replacement. Trichosporon beigelii was isolated from the blood, a peripheral thrombus, and the removed prosthesis. After two valve prosthesis replacements and prolonged antifungal therapy, the patient survived for four years, but eventually died as a consequence of multiple septic complications due to the same organism. To the authors' knowledge, this is the longest survival time of any reported case of Trichosporon prosthetic valve endocarditis.
Martinez-Lacasa
J
J
Department of Internal Medicine, Hospital de Bellvitge Prínceps D'Espanya, Barcelona, Spain.
Maña
J
J
Niubó
R
R
Rufi
G
G
Saez
A
A
Fernández-Nogués
F
F
D000666:Amphotericin B / Q000627:therapeutic use; D004696:Endocarditis / Q000188:drug therapy / Q000382:microbiology*; D015725:Fluconazole / Q000627:therapeutic use; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology*; D011379:Prognosis; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000382:microbiology*; D013030:Spain / Q000453:epidemiology; D013997:Time Factors; D014250:Trichosporon / Q000302:isolation & purification*
D000666:Amphotericin B; D015725:Fluconazole