Weight and radioactivity of the organs of progeny after 5-HT and/or Na2H32PO4 treatment of pregnant mice.
In 30-day-old offspring of mice treated with 5-HT and/or Na2H32PO4, there was a decrease in the fresh weight of the organs, being more noticeable in males than in females. In relation to a group injected with Na2H32PO4 and that to which both 5-HT and Na2H32PO4 were administered, a greater fresh weight of the organs in mice treated with 5-HT only was found. No differences in the radioactivity of 32P in the organs of 30-day-old offspring between the group of mice treated with Na2H32PO4 only and that injected with both 5-HT and Na2H32PO4, were observed.
Manowska
J
J
Department of Animal Physiology, Jagiellonian University, Kraków, Poland.
Mazur
L
L
D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development; D001835:Body Weight / Q000187:drug effects; D005260:Female; D006321:Heart / Q000033:anatomy & histology; D007668:Kidney / Q000033:anatomy & histology / Q000378:metabolism; D008099:Liver / Q000033:anatomy & histology / Q000378:metabolism; D008168:Lung / Q000033:anatomy & histology / Q000378:metabolism; D008431:Maternal-Fetal Exchange; D051379:Mice; D008810:Mice, Inbred C57BL; D009206:Myocardium / Q000378:metabolism; D009929:Organ Size / Q000187:drug effects; D010761:Phosphorus Radioisotopes / Q000493:pharmacokinetics / Q000633:toxicity*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*; D012701:Serotonin / Q000494:pharmacology*; D013154:Spleen / Q000033:anatomy & histology / Q000378:metabolism; D014018:Tissue Distribution
D010761:Phosphorus Radioisotopes; D012701:Serotonin