[Endocrinology 1990-1991].
The author presents an account of selected important findings in endocrinology during the last year. The mediator of action of STH, IGF-I, was tested as a protein anabolic in a child with Laron's nanism. STH is about to be tested as a geriatric drug. A non-peptide vasopressin antagonist was described. Melatonin is being tested in sleep disorders. A combination of methimazol and thyroxine is more suitable for treatment of Graves-Basedow's disease than the goitrogen alone. Dermal vasoconstriction can be an indicator of the effectiveness of glucocorticoids in asthma. Significant advances were made in the sphere of the new hormone, NO: it is not only an effective vasorelaxing agent but also a neuromodulator and participates in the natural lymphocytic cytotoxicity. Marked advances were made as regards knowledge of the endogenous ligand for benzodiazepine receptors.
Schreiber
V
V
Laborator pro endokrinologii a metabolismus pri III, interní klinice 1, lékarské fakulty, Univerzity Karlovy, Praha.
D004700:Endocrine System Diseases; D006728:Hormones; D006801:Humans
D006728:Hormones
Endokrinologie 1990-1991.