title: Primary hyperparathyroidism. Our experience.
abstract: We report our experience in the clinical presentation and management of 12 patients with primary hyperparathyroidism, who underwent successful surgery. Comparing our results with those previously reported in the literature, we have attempted to correlate the kind of parathyroid lesion, the magnitude of hypercalcemia and PTH increase, and clinical symptoms. Often these relationships are intriguing; we have tried to classify our patients describing four groups, according to clinical and humoral findings: 1) patients with very mild hypercalcemia and aspecific symptoms; 2) patients with a finding of recurrent hypercalcemia and prevalent renal involvement; 3) patients with severe hypercalcemia, plurisystemic involvement and general decay; 4) patients with medical emergencies. Finally, some considerations on rare histological pictures (hyperfunctioning carcinoma, oxyphil cell adenoma) are reported.
authors.affiliation: Catholic University School of Medicine, Rome, Italy.
authors.forename: L
authors.initials: L
authors.lastname: De Marinis
authors.forename: A
authors.initials: A
authors.lastname: Mancini
authors.forename: R
authors.initials: R
authors.lastname: Sciuto
authors.forename: F
authors.initials: F
authors.lastname: Calabrò
authors.forename: P
authors.initials: P
authors.lastname: Zuppi
authors.forename: C
authors.initials: C
authors.lastname: Fiumara
authors.forename: A
authors.initials: A
authors.lastname: Goglia
authors.forename: L
authors.initials: L
authors.lastname: Sofo
authors.forename: R
authors.initials: R
authors.lastname: Bellantone
authors.forename: F
authors.initials: F
authors.lastname: Crucitti
mesh_terms: D000236:Adenoma / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D000293:Adolescent; D000328:Adult; D002277:Carcinoma / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology; D006961:Hyperparathyroidism / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000097:blood; D010282:Parathyroid Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D016105:Parathyroidectomy
chemical_list: D010281:Parathyroid Hormone