[The immunological prognosis of complications in patients undergoing reconstructive operations after the radiation therapy of malignant tumors of the maxillofacial area and neck].
Immunologic studies were carried out in 55 patients with local malignant processes in the maxillofacial area and neck before and after surgery. The patients were divided into 2 groups: group 1 (N = 20) received no specific therapy before surgery, group 2 (n = 35) were administered radiotherapy in a total focal dose of 56-65 Gy before the operation. The findings evidence that radiotherapy augments B and T system immunodeficiency manifestations after surgical stress. Postoperative complications in the patients administered radiotherapy before surgery are due to not only immunodeficiency, but to the initial presence of an infective agent as well. Immunocorrective therapy before and after surgery may be recommended to patients whose immunity parameters are shifted.
Trufanov
V D
VD
Boĭkov
A N
AN
Simonova
A V
AV
Zandelov
V L
VL
Kulakov
A V
AV
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000917:Antibody Formation; D002294:Carcinoma, Squamous Cell / Q000276:immunology* / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D005153:Facial Neoplasms / Q000276:immunology* / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006258:Head and Neck Neoplasms / Q000276:immunology* / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D007111:Immunity, Cellular; D007573:Jaw Neoplasms / Q000276:immunology* / Q000532:radiotherapy / Q000601:surgery; D008297:Male; D008875:Middle Aged; D015166:Monitoring, Immunologic; D011183:Postoperative Complications / Q000517:prevention & control*; D011379:Prognosis
Immunologicheskoe prognozirovanie oslozhneniĭ u bol'nykh posle luchevoĭ terapii zlokachestvennykh opukholeĭ cheliustno-litsevoĭ oblasti i shei pri provedenii rekonstruktivnykh operatsiĭ.