[Comparison of the effects of the irritant action of different amounts of cooling mineral oil with biocides on the rabbit skin].
Effects of different concentrations of Emulgol EN-BIO C/88 oil on rabbit skin were studied. Experiments were carried out to examine oil irritancy to the skin and the inner surface of the ear skin subjected to a 24-hour closed exposure and repeated open exposure for 10 days, respectively. The data obtained have shown that 5 and 10 per cent emulsions of Emulgol EN-BIO C/88 produce mild skin irritation, while a 50 per cent emulsion and concentrate cause irritation of moderate degree. This means that the irritating potential of Emulgol depends on its concentration in oil-water emulsion. It is concluded that EN-BIO C/88 oil should be used in a 5 per cent concentration in industry.
Nowak
B
B
I Zakładu Higieny i Epidemiologii Slaskiej Akademii Medycznej w Katowicach.
Małecka
H
H
Miarczyńska-Jończyk
H
H
D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001673:Biodegradation, Environmental / Q000187:drug effects; D003343:Corrosion; D003877:Dermatitis, Contact / Q000209:etiology*; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D007509:Irritants / Q000008:administration & dosage / Q000009:adverse effects*; D008669:Metallurgy; D008899:Mineral Oil / Q000008:administration & dosage / Q000009:adverse effects*; D011044:Poland; D011817:Rabbits; D013997:Time Factors
D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D007509:Irritants; D008899:Mineral Oil
Porównanie działania drazniacego róznych stezeń olejów emulgujacych z biocydami na skóre królików.