title: Involvement of neutrophils in ischemia-reperfusion injury in the small intestine.
abstract: Reperfusion of the ischemic intestine results in injury to the microvasculature and mucosal membrane. Inflammatory mediators released as a consequence of oxygen radical formation at the time of reperfusion promote neutrophil adhesion and emigration in postcapillary venules. Agents that interfere with leukocyte adherence afford significant protection against reperfusion injury.
authors.affiliation: Department of Physiology and Biophysics, Louisiana State University Medical Center, Shreveport.
authors.forename: H
authors.initials: H
authors.lastname: Arndt
authors.forename: P
authors.initials: P
authors.lastname: Kubes
authors.forename: D N
authors.initials: DN
authors.lastname: Granger
mesh_terms: D000818:Animals; D015815:Cell Adhesion Molecules / Q000502:physiology; D005609:Free Radicals; D006098:Granulocytes / Q000502:physiology; D006801:Humans; D007422:Intestines / Q000098:blood supply*; D007511:Ischemia / Q000503:physiopathology*; D009504:Neutrophils / Q000502:physiology*; D010100:Oxygen / Q000502:physiology*; D015427:Reperfusion Injury / Q000503:physiopathology*
chemical_list: D015815:Cell Adhesion Molecules; D005609:Free Radicals; D010100:Oxygen