title: Synthesis of some 5-azaflavones.
abstract: Within a plan of researches concerning drugs with anti-ulcer activity, a series of 5-azaflavones has been prepared. In this first communication we report the relevant synthesis obtained by cyclization of appropriate beta-diketones in HCOOH at the boiling point. The beta-diketones have been obtained by Claisen condensation, starting from methyl 3-hydroxypicolinate and from appropriate aromatic or heterocyclic methylketone, using NaH as base.
authors.affiliation: Formenti Group, Research Laboratories, Origgio, VA, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Passarotti
authors.forename: G L
authors.initials: GL
authors.lastname: Bandi
authors.forename: L
authors.initials: L
authors.lastname: Citerio
authors.forename: M
authors.initials: M
authors.lastname: Valenti
mesh_terms: D000897:Anti-Ulcer Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001372:Aza Compounds / Q000032:analysis / Q000138:chemical synthesis* / Q000494:pharmacology; D005419:Flavonoids / Q000032:analysis / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000897:Anti-Ulcer Agents; D001372:Aza Compounds; D005419:Flavonoids