Syntheses of 2,6-dideoxy-6-fluoro-2-[(3R and 3S)-3- hydroxytetradecanamido]-3-O-[(3R)-3-(tetradecanoyloxy)tetra decanoyl]-D- glucopyranose 4-(dihydrogen phosphate) and 2-deoxy-2-[(3R and 3S)-3- hydroxytetradecanamido]-3-O-[(3R)-3-(tetradecanoyloxy)tetra decanoyl]- alpha-D-glucopyranosyl fluoride 4-(dihydrogen phosphate): fluorosugar analogues of GLA-60.
Kobayashi
Y
Y
New Lead Research Laboratories, Sankyo Company Ltd., Tokyo, Japan.
Ishida
N
N
Arai
M
M
Shiozaki
M
M
Hiraoka
T
T
Nishijima
M
M
Kuge
S
S
Otsuka
T
T
Akamatsu
Y
Y
D000818:Animals; D002236:Carbohydrate Conformation; D002460:Cell Line; D007202:Indicators and Reagents; D007536:Isomerism; D008050:Lipid A / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D008264:Macrophages / Q000187:drug effects; D051379:Mice; D015394:Molecular Structure; D015230:Prostaglandin D2 / Q000096:biosynthesis; D013329:Structure-Activity Relationship
D007202:Indicators and Reagents; D008050:Lipid A; C056260:GLA 60; C074481:2-deoxy-2-((3R)-3-hydroxytetradecanamido)-3-O-((3-tetradecanoyloxy)tetradecanoyl)glucopyranosyl fluoride 4-(dihydrogen phosphate); C074480:2,6-dideoxy-6-fluoro-2-(3-hydroxytetradecanamido)-3-O-((3-tetradecanoyloxy)tetradecanoyl)glucopyranose 4-(dihydrogen phosphate); D015230:Prostaglandin D2