title: Long-term survival of a patient with prosthetic valve endocarditis due to Trichosporon beigelii.
abstract: A case is described of a 49-year-old man with rheumatic aortic valve disease who developed endocarditis seven years after valvular replacement. Trichosporon beigelii was isolated from the blood, a peripheral thrombus, and the removed prosthesis. After two valve prosthesis replacements and prolonged antifungal therapy, the patient survived for four years, but eventually died as a consequence of multiple septic complications due to the same organism. To the authors' knowledge, this is the longest survival time of any reported case of Trichosporon prosthetic valve endocarditis.
authors.affiliation: Department of Internal Medicine, Hospital de Bellvitge Prínceps D'Espanya, Barcelona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Martinez-Lacasa
authors.forename: J
authors.initials: J
authors.lastname: Maña
authors.forename: R
authors.initials: R
authors.lastname: Niubó
authors.forename: G
authors.initials: G
authors.lastname: Rufi
authors.forename: A
authors.initials: A
authors.lastname: Saez
authors.forename: F
authors.initials: F
authors.lastname: Fernández-Nogués
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D004696:Endocarditis / Q000188:drug therapy / Q000382:microbiology*; D015725:Fluconazole / Q000627:therapeutic use; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology*; D011379:Prognosis; D016459:Prosthesis-Related Infections / Q000188:drug therapy / Q000382:microbiology*; D013030:Spain / Q000453:epidemiology; D013997:Time Factors; D014250:Trichosporon / Q000302:isolation & purification*
chemical_list: D000666:Amphotericin B; D015725:Fluconazole