The three-dimensional x-ray crystal structure of HIV-1 protease complexed with a hydroxyethylene inhibitor.
Graves
B J
BJ
Roche Research Center, Hoffmann-La Roche Inc., Nutley, New Jersey 07110.
Hatada
M H
MH
Miller
J K
JK
Graves
M C
MC
Roy
S
S
Cook
C M
CM
Kröhn
A
A
Martin
J A
JA
Roberts
N A
NA
D001665:Binding Sites; D016333:HIV Protease / Q000737:chemistry*; D017320:HIV Protease Inhibitors; D006860:Hydrogen Bonding; D015394:Molecular Structure; D009842:Oligopeptides / Q000737:chemistry / Q000494:pharmacology; D011480:Protease Inhibitors / Q000737:chemistry / Q000494:pharmacology; D011487:Protein Conformation; D014961:X-Ray Diffraction
D017320:HIV Protease Inhibitors; D009842:Oligopeptides; D011480:Protease Inhibitors; C074409:Ro 31-8588; D016333:HIV Protease