title: [Corynebacterium D2 as a ureolytic organism: report of 5 cases].
abstract: Corynebacterium D2, a saprophytic microorganism of skin, causes alkaline encrusted cystitis in patients with a previous bladder injury. In 5 patients that had presented this nosological entity, these gram-positive rods were isolated in urine cultures and calculi. Four patients had undergone urological instrumentation maneuvers and one patient (female) had a history of recurrent cystitis from gram-negative bacteria. Corynebacterium D2 grows slowly and under certain conditions, as those described above, must be considered pathological despite counts of less than 100,000/ufc-cc. It is ureolytic and highly resistant to antibiotics. The synergistic effects of antimicrobials, acetohydroxamic acid and transurethral resection of the lithiasic plaques achieve satisfactory treatment of alkaline encrusted cystitis from Corynebacterium D2.
authors.affiliation: Servicio de Urología II, Complejo Hospitalario de León, España.
authors.forename: F
authors.initials: F
authors.lastname: García Díez
authors.forename: I
authors.initials: I
authors.lastname: Fernández Natal
authors.forename: R
authors.initials: R
authors.lastname: Guerreiro González
authors.forename: C
authors.initials: C
authors.lastname: González del Valle
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001431:Bacteriological Techniques; D003352:Corynebacterium / Q000378:metabolism / Q000472:pathogenicity*; D003354:Corynebacterium Infections / Q000209:etiology / Q000382:microbiology; D003556:Cystitis / Q000209:etiology / Q000382:microbiology*; D005260:Female; D006801:Humans; D008274:Magnesium / Q000378:metabolism; D017616:Magnesium Compounds; D008297:Male; D008875:Middle Aged; D010710:Phosphates / Q000378:metabolism; D000069877:Struvite; D014508:Urea / Q000378:metabolism*; D014545:Urinary Calculi / Q000382:microbiology*; D014546:Urinary Catheterization / Q000009:adverse effects
chemical_list: D017616:Magnesium Compounds; D010710:Phosphates; D014508:Urea; D000069877:Struvite; D008274:Magnesium
vernacular_title: Corynebacterium D2 como germen ureolítico: a propósito de cinco casos.