[Diagnostic evaluation of the determination of antibodies to purified protein derivative in tuberculosis].
The results with ELISA method showed the levels of the antibody to PPD in exudates of TB group were significantly higher than those of non-TB group (P less than 0.001). When OD value greater than 0.2 and greater than 0.35 were chosen as the positive criteria, for diagnosing tuberculous meningitis and other tuberculous, the sensitivity would be 79.3% and 86.6%, respectively; the specificity would be 93.3% and 86.0%, respectively. Meanwhile tuberculosis could be suggested when the ratio of the antibody level in exudate to that in serum is greater than 1. The authors think that the detection of the antibody to PPD in exudates might be a supplemental diagnostic tool for tuberculosis.
Li
J W
JW
First Affiliated Hospital, West China University of Medical Sciences.
D000907:Antibodies, Bacterial / Q000032:analysis*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D010495:Pericarditis, Tuberculous / Q000175:diagnosis; D014395:Peritonitis, Tuberculous / Q000175:diagnosis; D014373:Tuberculin / Q000276:immunology*; D014376:Tuberculosis / Q000175:diagnosis*; D014390:Tuberculosis, Meningeal / Q000175:diagnosis; D014396:Tuberculosis, Pleural / Q000175:diagnosis
D000907:Antibodies, Bacterial; D014373:Tuberculin