title: [Neonatal infections and premature rupture of fetal membranes].
abstract: The premature rupture of the membranes is still a cause of concern due to the related risk of infection and respiratory disorders. The study included sixty-two neonates whose mothers had ruptured their membranes for at least 48 hours (group A) and 42 neonates with a high risk of infection (low birth weight, prematurity) (group B) in order to assess whether antibiotic prophylaxis used in pregnant women with premature rupture of the membranes is sufficient to reduce the risk of severe neonatal infection. The results obtained show that there is an increased frequency of RDS, jaundice and mortality in group A, whereas in group B there was a greater frequency of sepsis and urinary tract infections. Antibiotic prophylaxis therefore allows the frequency of neonatal infections following the rupture of membranes to be reduced, thus enabling the birth to be delayed in order to induce pulmonary maturity.
authors.affiliation: Istituto di Pediatria Clinica e Preventiva, Università degli Studi di Bari.
authors.forename: O
authors.initials: O
authors.lastname: Montagna
authors.forename: A
authors.initials: A
authors.lastname: Giusti
authors.forename: F
authors.initials: F
authors.lastname: Baisi
authors.forename: L
authors.initials: L
authors.lastname: Napolitano
authors.forename: A
authors.initials: A
authors.lastname: Mautone
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000209:etiology* / Q000517:prevention & control; D001724:Birth Weight; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000150:complications*; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000209:etiology* / Q000401:mortality / Q000517:prevention & control; D007235:Infant, Premature, Diseases / Q000209:etiology / Q000401:mortality / Q000517:prevention & control; D011247:Pregnancy
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Infezioni neonatali e rottura prematura delle membrane.