[Magnesium hydroxide and aluminum hydroxide in the treatment of gastroesophageal reflux].
Fifteen children with gastro-esophageal reflux took part in a treatment trial with a regimen of magnesium hydroxide and aluminium hydroxide for 8 weeks period (700 mmol/1.73 mq/die). All children were evaluated clinically and underwent a 24-hour continuous esophageal pH-monitoring both at diagnosis and after 8 weeks of treatment. After therapy 12/15 children were cured and 3/15 improved. Moreover the total percentage of time during which pH was less than 4, the number of reflux episodes and the number of refluxes lasting than 5' recorded during 24-hour continuous esophageal pH-monitoring were significantly reduced after treatment. The Authors conclude that antacids in large quantities are effective in medical treatment of gastro-esophageal reflux.
Iacono
G
G
Cattedra di Patologia Medica II, Ospedale Pediatrico G. Di Cristina, Palermo.
Carroccio
A
A
Montalto
G
G
Cavataio
F
F
Ippolito
S
S
Kazmierska
I
I
Balsamo
V
V
D000536:Aluminum Hydroxide / Q000627:therapeutic use*; D000863:Antacids / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004338:Drug Combinations; D005260:Female; D005764:Gastroesophageal Reflux / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007223:Infant; D008276:Magnesium Hydroxide / Q000627:therapeutic use*; D008297:Male; D008991:Monitoring, Physiologic; D013997:Time Factors
D000863:Antacids; D004338:Drug Combinations; C013591:aluminum hydroxide, magnesium hydroxide, drug combination; D000536:Aluminum Hydroxide; D008276:Magnesium Hydroxide
Idrossido di magnesio e idrossido di alluminio nel trattamento del reflusso gastro-esofageo.