title: [Synthesis of "danshensu" derivatives].
abstract: This paper describes the synthesis of alpha-nicotinyloxy-beta-(substituted phenyl) propionic acid and alpha-(o-acetoxy)benzoyloxy-beta-phenyl propionic acid. They were obtained in six steps starting from benzaldehyde or substituted benzaldehyde. The preliminary pharmacological tests show that all compounds were effective for inhibition of rabbit platelet aggregation.
authors.affiliation: School of Pharmacy, Shanghai Medical University.
authors.forename: J M
authors.initials: JM
authors.lastname: Yu
authors.forename: F
authors.initials: F
authors.lastname: Xue
authors.forename: H J
authors.initials: HJ
authors.lastname: Dai
mesh_terms: D000818:Animals; D007773:Lactates / Q000138:chemical synthesis*; D009539:Nicotinic Acids / Q000138:chemical synthesis* / Q000494:pharmacology; D010666:Phenylpropionates / Q000138:chemical synthesis* / Q000494:pharmacology; D010975:Platelet Aggregation Inhibitors / Q000138:chemical synthesis*; D011817:Rabbits
chemical_list: D007773:Lactates; D009539:Nicotinic Acids; D010666:Phenylpropionates; D010975:Platelet Aggregation Inhibitors; C035055:3,4-dihydroxyphenyllactic acid; C073953:alpha-(2-acetoxy)benzoyloxy-beta-phenylpropionic acid