title: [The dynamics of the humoral immune response to mycobacterial antigens in mice].
abstract: The main regularities of humoral immune response to mycobacterial antigens have been studied in experiments on BALB/c mice immunized with live and thermoinactivated Mycobacterium tuberculosis, var. bovis. As shown in this study, the maximum level of serum antibodies to mycobacterial antigen is achieved in two weeks after immunization irrespective of the dose and viability or mycobacteria, then follows a decrease in the antibody level. The absence of uniformity in the dependence of primary immune response and the formation of immunological memory on the dose and viability of mycobacteria has been demonstrated.
authors.forename: K P
authors.initials: KP
authors.lastname: Liashchenko
authors.forename: S A
authors.initials: SA
authors.lastname: Bobrovnik
authors.forename: S V
authors.initials: SV
authors.lastname: Komissarenko
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D000917:Antibody Formation / Q000276:immunology; D000918:Antibody Specificity / Q000276:immunology; D000936:Antigen-Antibody Complex / Q000097:blood; D000942:Antigens, Bacterial / Q000276:immunology*; D001500:BCG Vaccine / Q000276:immunology; D004306:Dose-Response Relationship, Immunologic; D007114:Immunization; D007117:Immunization, Secondary; D051379:Mice; D008807:Mice, Inbred BALB C; D009163:Mycobacterium bovis / Q000276:immunology*; D013997:Time Factors
chemical_list: D000907:Antibodies, Bacterial; D000936:Antigen-Antibody Complex; D000942:Antigens, Bacterial; D001500:BCG Vaccine
vernacular_title: Dinamika gumoral'nogo immunnogo otveta na antigeny mikobakteriĭ u mysheĭ.