title: Adenosine deaminase, Ada, is in mouse chromosome 2H3, and is not allelic with wasted, wst.
abstract: The adenosine deaminase locus (Ada) in the mouse has been localized by in situ hybridization to band 2H3. Linkage analysis of backcross data has shown that Ada is 13.8 +/- 2.7 cM from the coat texture mutant, ragged, Ra. From the results of earlier work (Abbott, C. M., et al., Proc. Natl. Acad. Sci. USA 83:693, 1986), it had been suggested that wst was a low-activity allele of Ada, but this cannot be so because Ada and wst have been found to be nonallelic.
authors.affiliation: MRC Radiobiology Unit, Chilton, Didcot, U.K.
authors.forename: C M
authors.initials: CM
authors.lastname: Abbott
authors.forename: E P
authors.initials: EP
authors.lastname: Evans
authors.forename: M
authors.initials: M
authors.lastname: Burtenshaw
authors.forename: S T
authors.initials: ST
authors.lastname: Ball
authors.forename: C J
authors.initials: CJ
authors.lastname: Skidmore
authors.forename: J
authors.initials: J
authors.lastname: Jones
authors.forename: J
authors.initials: J
authors.lastname: Peters
mesh_terms: D000243:Adenosine Deaminase / Q000235:genetics*; D000483:Alleles; D000818:Animals; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D008040:Genetic Linkage; D051379:Mice / Q000235:genetics*; D008809:Mice, Inbred C3H / Q000235:genetics; D008810:Mice, Inbred C57BL / Q000235:genetics; D008817:Mice, Mutant Strains / Q000235:genetics; D009693:Nucleic Acid Hybridization
chemical_list: D000243:Adenosine Deaminase