[Primary hypothyroidism and glomerular involvement].
Association between auto-immune dysthyroidism and glomerulonephritis is quite rare. The authors report 3 cases with proteinuria varying from 2.72 to 6.06 g/day and hypothyroidism. Nephrotic syndrome was found in 2 cases and thyroid auto-antibodies (microsomal and thyroglobulin) and circulating immun complexes (C.I.C.) in 1 case, complement fractions C3 and C4 were normal in all cases. Renal biopsy showed membranous glomerulonephritis in 2 cases and minimal lesions in the third case. Proteinuria disappeared with glucocorticoids and thyroxine in 1 case, with thyroxine alone in an other case and persisted in the third case with normal thyroid function.
Mahjoub
S
S
Service de Médecine Interne et Néphrologie de Monastir, Tunisie.
Ben Dhia
N
N
Achour
A
A
Zebidi
A
A
Frih
A
A
Elmay
M
M
D000328:Adult; D005260:Female; D005921:Glomerulonephritis / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007037:Hypothyroidism / Q000150:complications*; D008297:Male; D008875:Middle Aged
Hypothyroïdie primitive et atteinte glomérulaire.