title: Effects of Na+ on the persistence length and excluded volume of T7 bacteriophage DNA.
abstract: Total intensity, Rayleigh light scattering has been used to measure the rms radius, second virial coefficient, persistence length, and excluded volume of homogeneous T7 bacteriophage DNA as a function of Na+ concentration (0.005 to 3.0 M). All parameters decrease sharply as [Na+] increases, and tend to level off at high Na+. The variation of persistence length with [Na+] is consistent with predictions from counterion condensation theory.
authors.affiliation: Department of Biochemistry, Case Western Reserve University, Cleveland, Ohio 44106-4935.
authors.forename: E S
authors.initials: ES
authors.lastname: Sobel
authors.forename: J A
authors.initials: JA
authors.lastname: Harpst
mesh_terms: D004279:DNA, Viral / Q000737:chemistry* / Q000187:drug effects; D008433:Mathematics; D008962:Models, Theoretical; D009690:Nucleic Acid Conformation; D012542:Scattering, Radiation; D012964:Sodium / Q000494:pharmacology*; D013604:T-Phages / Q000378:metabolism*
chemical_list: D004279:DNA, Viral; D012964:Sodium