[The antioxidant properties of parmidine in a toxic lesion of the liver].
The experiments on rats with toxic lesions of the liver induced by tetrachlorinemethane showed that parmidine (pyridinolcarbamat) promotes the reduction of the activity of lipid peroxidation in the liver tissue homogenates and erythrocytes. The pronounced tendency towards normalization of free-radical oxidation correlated with the positive dynamics of the histological picture of the liver.
Riabkov
A N
AN
Uzbekova
D G
DG
Artem'eva
G B
GB
Nikulin
A A
AA
D000818:Animals; D000975:Antioxidants / Q000627:therapeutic use*; D002252:Carbon Tetrachloride Poisoning / Q000188:drug therapy* / Q000378:metabolism; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy* / Q000378:metabolism; D004353:Drug Evaluation, Preclinical; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008297:Male; D011727:Pyridinolcarbamate / Q000627:therapeutic use*; D051381:Rats; D013997:Time Factors
D000975:Antioxidants; D011727:Pyridinolcarbamate
Izuchenie antioksidantnykh svoĭstv parmidina v usloviiakh tokischeskogo porazheniia pecheni.