[HLA antigens and prognosis of the development of pneumoconiosis].
Basing on the studies of the HLA spectra of the A, B and C locuses in 102 pneumoconiosis patients working at a machine-building plant, and 112 healthy persons, the author proposes a technique for calculating the integral coefficient of pneumoconiosis risks. The integral coefficient 0-2 provides a criterion for distinguishing between healthy and pneumoconiosis cases. The coefficient can be used in screening of workers engaged in dust-exposed profession in machine-building industries, who may require preventive medical examination performed on a regular basis.
Nabrinskiĭ
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SI
D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D004198:Disease Susceptibility; D004391:Dust / Q000009:adverse effects; D004738:Engineering; D006680:HLA Antigens / Q000032:analysis / Q000235:genetics*; D015234:HLA-A Antigens / Q000032:analysis / Q000235:genetics; D015235:HLA-B Antigens / Q000032:analysis / Q000235:genetics; D015236:HLA-C Antigens / Q000032:analysis / Q000235:genetics; D006801:Humans; D008669:Metallurgy; D011009:Pneumoconiosis / Q000209:etiology* / Q000235:genetics; D011379:Prognosis; D012307:Risk Factors; D014455:Ukraine
D000395:Air Pollutants, Occupational; D004391:Dust; D006680:HLA Antigens; D015234:HLA-A Antigens; D015235:HLA-B Antigens; D015236:HLA-C Antigens
Antigeny HLA i otsenka prognoza razvitiia pnevmokonioza.