title: Two new trichothecenes from Fusarium sporotrichioides.
abstract: Two new trichothecenes, 8-n-pentanoylneosolaniol and 8-n-hexanoylneosolaniol, were isolated from corn grits cultured with Fusarium sporotrichioides. The structures of these compounds were elucidated using gc-ms, nmr, X-ray crystallography, and other spectroscopic techniques. Seven known trichothecenes were also isolated, and the relative cytotoxicity of these nine trichothecenes in cultured baby hamster kidney (BHK-21) cells was determined.
authors.affiliation: Veterinary Medical Diagnostic Laboratory, University of Missouri, Columbia 65211.
authors.forename: E
authors.initials: E
authors.lastname: Bekele
authors.forename: A A
authors.initials: AA
authors.lastname: Rottinghaus
authors.forename: G E
authors.initials: GE
authors.lastname: Rottinghaus
authors.forename: H H
authors.initials: HH
authors.lastname: Casper
authors.forename: D M
authors.initials: DM
authors.lastname: Fort
authors.forename: C L
authors.initials: CL
authors.lastname: Barnes
authors.forename: M S
authors.initials: MS
authors.lastname: Tempesta
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D006224:Cricetinae; D005670:Fusarium / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D009183:Mycotoxins / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D014255:Trichothecenes / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity
chemical_list: D009183:Mycotoxins; D014255:Trichothecenes; C073624:8-pentanoylneosolaniol; C073623:8-hexanoylneosolaniol