title: Local thrombolytic therapy as a support for catheter embolectomy in limb arterial occlusions.
abstract: Eleven patients with acute arterial occlusion of the lower limb were treated by standard balloon catheter embolectomy. Residual thrombus seen in intraoperative arteriograms was treated with streptokinase: after an initial dose of 10.000 IU, streptokinase was infused intra-arterially in a dose of 5.000-10.000 IU/hour. The average infusion time was 40 hours (range 15-94 hours) and the total amount of streptokinase used was on average 210.000 IU (range 35.000-470.000 IU). All legs were saved. Complete recanalization occurred in eight patients and partial recanalization in three patients. Excluding three inguinal haematomas no other complications occurred.
authors.affiliation: Department of Surgery, Central Hospital of Keski-Pohjanmaa, Kokkola, Finland.
authors.forename: A
authors.initials: A
authors.lastname: Alavaikko
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging / Q000628:therapy*; D002406:Catheterization, Peripheral; D003131:Combined Modality Therapy; D004617:Embolism / Q000000981:diagnostic imaging / Q000628:therapy*; D005260:Female; D006801:Humans; D007511:Ischemia / Q000000981:diagnostic imaging / Q000628:therapy*; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D013300:Streptokinase / Q000008:administration & dosage*; D015912:Thrombolytic Therapy / Q000379:methods*
chemical_list: D013300:Streptokinase