title: Telomeres--what's new at the end?
abstract: Telomeres are specialized chromatin domains located at the ends of chromosomes. They are involved in chromosome replication, stability and localization in the nucleus. In addition to these functions, recent work suggests that telomeres are involved in such superficially diverse cellular phenomena as ageing, cancer, nuclear architecture and nuclear/cellular division.
authors.affiliation: Department of Zoology and Genetics, Iowa State University, Ames 50011.
authors.forename: E R
authors.initials: ER
authors.lastname: Henderson
authors.forename: D D
authors.initials: DD
authors.lastname: Larson
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure; D004261:DNA Replication; D004268:DNA-Binding Proteins / Q000145:classification / Q000378:metabolism; D004330:Drosophila / Q000235:genetics; D009690:Nucleic Acid Conformation; D015800:Protozoan Proteins / Q000145:classification / Q000378:metabolism; D012091:Repetitive Sequences, Nucleic Acid; D012441:Saccharomyces cerevisiae / Q000235:genetics; D016615:Telomere / Q000502:physiology / Q000648:ultrastructure*
chemical_list: D004268:DNA-Binding Proteins; D015800:Protozoan Proteins