Objective measures of ocular irritation as a consequence of hydrogen sulphide exposure.
Hydrogen sulphide (H2S) exposure has been reported to adversely affect the eyes. Objective information regarding the extent of injury relative to varied exposure concentrations of H2S has not been published. The exfoliative eye cytology procedure has been demonstrated to provide quantitative information regarding the degree of ocular irritation and to allow for comparisons to be made between the irritants. This paper evaluates this procedure's efficiency in determining the degree of ocular irritation resulting from hydrogen sulphide exposure in rats.
Lefebvre
M
M
Alberta Environmental Centre, Animal Sciences Division, Vegreville, Canada.
Yee
D
D
Fritz
D
D
Prior
M G
MG
D000818:Animals; D002452:Cell Count / Q000187:drug effects; D005123:Eye / Q000187:drug effects* / Q000473:pathology; D006862:Hydrogen Sulfide / Q000633:toxicity*; D007509:Irritants / Q000633:toxicity*; D008297:Male; D051381:Rats; D011916:Rats, Inbred F344
D007509:Irritants; D006862:Hydrogen Sulfide