[Free radical oxidation of red blood cell membrane lipid structures as a trigger mechanism of an increase in red blood cell membrane permeability during blood coagulation in vitro].
The study of venous blood samples from 50 clinically normal subjects has shown that free radical oxidation of red blood cell membrane lipid structure induced by the blood sample contact with atmospheric oxygen serves a trigger rising the membrane permeability during blood coagulation in vitro. Activation of endogenous phospholipase A2 is a process dependent on the increase of intraerythrocytic concentration of calcium ions.
Bezrukova
G A
GA
D001777:Blood Coagulation / Q000502:physiology*; D002463:Cell Membrane Permeability / Q000502:physiology*; D004910:Erythrocyte Membrane / Q000737:chemistry / Q000378:metabolism*; D005609:Free Radicals / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D008563:Membrane Lipids / Q000097:blood*; D010084:Oxidation-Reduction
D005609:Free Radicals; D008563:Membrane Lipids
Svobodnoradikal'noe okislenie lipidnykh struktur membran éritrotsitov kak puskovoĭ mekhanizm povysheniia membrannoĭ pronitsaemosti krasnykh kletok krovi pri ee svertyvanii in vitro.