title: Actinomycosis of the brain.
abstract: Actinomyces species are rare but treatable causes of central nervous system infection. A case of actinomycotic cerebral abscess is reported. The primary source of infection was probably the lung based on radiological findings although culture of the bronchial brushings was negative. The patient had surgical excision and repeated drainage with two prolonged causes of antibiotic therapy. At follow-up examination 36 months later, the patient was well except for a residual left hemiplegia. Diagnosis of cerebral actinomycosis can be made by anaerobic culture of the appropriate specimens or on histologic grounds. Optimal management combines adequate surgical drainage and prolonged antibiotic therapy.
authors.affiliation: Department of Medicine II, Tan Tock Seng Hospital, Singapore.
authors.forename: H M
authors.initials: HM
authors.lastname: Oh
authors.forename: W Y
authors.initials: WY
authors.lastname: Cheong
authors.forename: K K
authors.initials: KK
authors.lastname: Tan
authors.forename: C S
authors.initials: CS
authors.lastname: Sim
authors.forename: F J
authors.initials: FJ
authors.lastname: Jayaratnam
mesh_terms: D000196:Actinomycosis / Q000175:diagnosis*; D000328:Adult; D001922:Brain Abscess / Q000175:diagnosis* / Q000382:microbiology; D004322:Drainage; D006801:Humans; D008297:Male; D014057:Tomography, X-Ray Computed