title: A device for experimental radiosurgery.
abstract: As radiosurgery evolves into a widely available treatment modality for a variety of intracranial lesions, the need for basic research concerning the radiobiology of high-dose single-fraction ionizing radiation becomes crucial. A device especially designed for experimental radiosurgery in the cat is described. It incorporates basic parts of the Kopf stereotactic frame for accurate target positioning. A motorized pendular movement of the machine is used to describe a radiation arc, while the radiation source (either a linear accelerator or a cobalt machine) remains stationary. The pathway of the different radiation arcs is modified by rotation of the animal platform around the machine isocenter. Mechanical accuracy tests have shown a maximal alignment error of 0.15 mm, comparing favorably with that reported for modern clinical radiosurgical systems.
authors.affiliation: Department of Radiation Oncology, University of Florida, Gainesville.
authors.forename: F
authors.initials: F
authors.lastname: Bova
authors.forename: R
authors.initials: R
authors.lastname: Spiegelmann
authors.forename: W A
authors.initials: WA
authors.lastname: Friedman
mesh_terms: D000818:Animals; D002415:Cats; D003037:Cobalt Radioisotopes; D004867:Equipment Design; D010315:Particle Accelerators / Q000295:instrumentation*; D016634:Radiosurgery / Q000295:instrumentation*
chemical_list: D003037:Cobalt Radioisotopes