title: Atypical features of primary hyperoxaluria in end-stage renal disease.
abstract: Two case histories of patients with end-stage renal disease subsequently found to have primary hyperoxaluria are reported. In the setting of renal failure, the diagnosis is both difficult, due to diminished oxalate excretion, and important, because of frequent graft loss due to oxalate deposition after renal transplantation. The diagnosis was obtained by renal and bone biopsies. Plasma oxalate levels were normal in one patient and the other patient presented with extensive cystic bone lesions. Primary hyperoxaluria should be considered whenever nephrocalcinosis and/or nephrolithiasis are associated with end-stage renal disease.
authors.affiliation: Renal Unit, King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia.
authors.forename: M M
authors.initials: MM
authors.lastname: Absy
mesh_terms: D000328:Adult; D001706:Biopsy; D001842:Bone and Bones / Q000473:pathology; D005260:Female; D006801:Humans; D006960:Hyperoxaluria, Primary / Q000150:complications / Q000175:diagnosis*; D007668:Kidney / Q000473:pathology; D007669:Kidney Calculi / Q000209:etiology; D007676:Kidney Failure, Chronic / Q000209:etiology* / Q000601:surgery; D016030:Kidney Transplantation / Q000473:pathology; D008297:Male; D009397:Nephrocalcinosis / Q000209:etiology; D010070:Oxalates / Q000097:blood*
chemical_list: D010070:Oxalates