Biliary strictures in hepatic transplantation.
Between August 1985 and December 1990, 198 liver transplantations were performed. Among 18 patients, 20 biliary strictures were identified, which were categorized as anastomotic (n = 6), nonanastomotic central hilar (n = 8), and nonanastomotic peripheral (n = 6). Pretransplant disease, hepatic artery patency, presence of acute or chronic rejection, and donor cold ischemia times were tabulated for each case. Among the six patients with peripheral strictures, three had sclerosing cholangitis prior to transplantation. Three patients with nonanastomotic strictures experienced chronic rejection. The mean cold ischemia time for patients with nonanastomotic strictures was 9.75 hours versus 8.1 hours for nonstrictured transplants (P = .025). Balloon dilation was performed in 13 patients; follow-up longer than 6 months was available for nine patients. Dilation was successful in four cases. Among the five failures, only one patient has needed surgery. An association was noted between nonanastomotic biliary strictures and prolonged donor cold ischemia time, between peripheral nonanastomotic strictures and pretransplant sclerosing cholangitis, and between nonanastomotic strictures and chronic rejection. Percutaneous balloon dilation was found useful in the treatment of the strictured transplant.
McDonald
V
V
Department of Diagnostic Radiology and Nuclear Medicine, Rush-Presbyterian-St Luke's Medical Center, Chicago, IL 60612.
Matalon
T A
TA
Patel
S K
SK
Brunner
M C
MC
Sankary
H
H
Foster
P
P
Williams
J
J
D001660:Biliary Tract Diseases / Q000453:epidemiology / Q000209:etiology*; D003251:Constriction, Pathologic / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D016031:Liver Transplantation; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies