title: [The cardioprotective action of quercetin in experimental occlusion and reperfusion of the coronary artery in dogs].
abstract: In experimental myocardial infarction in dogs caused by 60-minute occlusion of the coronary artery with the subsequent 24-hour reperfusion, the administration of quercetin solution (50 mg/kg) was found to improve the contractile function of the left ventricular myocardium, to decrease the incidence of heart rate and conductivity disorders, to contribute to limitation of the ischemic damage area, to exert the protective effect on the ultrastructure of the coronary arteries that can promote the preservation of the vessels' integrity, the improvement of the coronary circulation and the prevention of intravascular thrombus formation.
authors.forename: Iu N
authors.initials: IuN
authors.lastname: Kolchin
authors.forename: N P
authors.initials: NP
authors.lastname: Maksiutina
authors.forename: P P
authors.initials: PP
authors.lastname: Balanda
authors.forename: A I
authors.initials: AI
authors.lastname: Luĭk
authors.forename: V N
authors.initials: VN
authors.lastname: Bulakh
authors.forename: A A
authors.initials: AA
authors.lastname: Moĭbenko
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology; D006328:Cardiac Catheterization; D003327:Coronary Disease / Q000188:drug therapy* / Q000503:physiopathology; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D005260:Female; D006321:Heart / Q000187:drug effects* / Q000503:physiopathology; D008297:Male; D008854:Microscopy, Electron; D009203:Myocardial Infarction / Q000188:drug therapy / Q000503:physiopathology; D015428:Myocardial Reperfusion Injury / Q000503:physiopathology / Q000517:prevention & control*; D009206:Myocardium / Q000648:ultrastructure; D011794:Quercetin / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D011794:Quercetin
vernacular_title: Kardioprotektornoe deĭstvie kvertsetina pri éksperimental'noĭ okkliuzii i reperfuzii koronarnoĭ arterii u sobak.