Calprotectin in cerebrospinal fluid of the HIV infected: a diagnostic marker of opportunistic central nervous system infection?
The calprotectin level in the cerebrospinal fluid (CSF) of 15 HIV positive patients with symptoms from the central nervous system (CNS) was measured. All 5 patients with opportunistic infections had levels above the reference range and all 10 patients with HIV associated encephalopathy had levels within the reference range. Thus, the calprotectin level in CSF can be of diagnostic value in differentiating between HIV associated encephalopathy and opportunistic infection in the HIV positive patient with symptoms from the CNS.
Dunlop
O
O
Department of Infectious Diseases, Ullevaal University Hospital, Oslo, Norway.
Bruun
J N
JN
Myrvang
B
B
Fagerhol
M K
MK
D015526:AIDS Dementia Complex / Q000175:diagnosis; D001927:Brain Diseases / Q000134:cerebrospinal fluid / Q000150:complications / Q000175:diagnosis*; D015816:Cell Adhesion Molecules, Neuronal / Q000134:cerebrospinal fluid*; D003937:Diagnosis, Differential; D015658:HIV Infections / Q000134:cerebrospinal fluid / Q000150:complications*; D006801:Humans; D007124:Immunoenzyme Techniques; D039841:Leukocyte L1 Antigen Complex; D016919:Meningitis, Cryptococcal / Q000150:complications / Q000175:diagnosis; D009894:Opportunistic Infections / Q000134:cerebrospinal fluid / Q000150:complications / Q000175:diagnosis*; D012189:Retrospective Studies
D015816:Cell Adhesion Molecules, Neuronal; D039841:Leukocyte L1 Antigen Complex