[The presence of an ovarian granulocytic sarcoma concurrent with a type M2 acute myeloblastic leukemia: a case].
The authors report a case of granulosa cell tumor principally located in the ovary associated with M2 type acute myeloblastic leukemia (AML) in a trisomy 22 patients. Surgery and chemotherapy were combined with a bone marrow allograft. Frequency of granulosa cell tumor is 8 percent or less of AML cases. Diagnosis is particularly difficult when haematologic expression occurs late in the disease course. An immunohistochemical work-up is required in these cases. Aetiopathogenesis is discussed. Treatment relies essentially on chemotherapy. The prognostic is variable according to different case reports in the literature.
Avigdor
S
S
Service de Gynécologie-Obstétrique B, CHR Orléans.
du Rouchet
E
E
Michenet
P
P
Grossetti
D
D
Lucas
V
V
D000328:Adult; D002892:Chromosomes, Human, Pair 22; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000473:pathology*; D015470:Leukemia, Myeloid, Acute / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000473:pathology*; D014314:Trisomy
Localisation ovarienne d'un sarcome granulocytaire contemporain d'une leucémie aiguë myéloblastique type M2: un cas.