title: High grade atrioventricular heart block in 2 adults with systemic lupus erythematosus.
abstract: We describe 2 patients with systemic lupus erythematosus (SLE) and high grade atrioventricular (AV) block. In one patient anti-Ro antibodies were positive. This antibody has been associated with congenital complete heart block in children of mothers with SLE; however, its role in adult high grade AV block is not clear. We reviewed the 8 published cases of adults with SLE and high grade AV block. The possible mechanisms that could be implicated in the pathology of high grade AV block are discussed.
authors.affiliation: Department of Internal Medicine, Hospital General Vall d'Hebron, Barcelona, Spain.
authors.forename: X
authors.initials: X
authors.lastname: Martinez-Costa
authors.forename: J
authors.initials: J
authors.lastname: Ordi
authors.forename: J
authors.initials: J
authors.lastname: Barberá
authors.forename: A
authors.initials: A
authors.lastname: Selva
authors.forename: J
authors.initials: J
authors.lastname: Bosch
authors.forename: M
authors.initials: M
authors.lastname: Vilardell
mesh_terms: D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D004562:Electrocardiography; D005260:Female; D006327:Heart Block / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*
chemical_list: D000974:Antibodies, Antinuclear; C035356:SS-A antibodies