[Interspecies mouse-mink hybridomas as producers of mink immunoglobulin].
The work is aimed at establishing the interspecies mouse-mink hybridomas from the fusion of American mink B-lymphocytes with the murine cell line NSO. The hybridoma (lime 10-B5) continued to secrete mink immunoglobulin L-chains in the culture for 6 months with constant reclonings. The hybridoma clone was characterized by a decrease in the secretory activity of cells. The karyological study et this clone has not reliably revealed the mink chromosomes in the genome of hybrid cells.
Ufimtseva
E G
EG
Galakhar'
N L
NL
D000818:Animals; D006825:Hybridomas / Q000276:immunology*; D007136:Immunoglobulins / Q000096:biosynthesis*; D051379:Mice; D008907:Mink / Q000276:immunology*
D007136:Immunoglobulins
Mezhvidovye gibridomy mysh'--norka--produtsenty noroch'evo immunoglobulina.