Granulocyte collection.
Techniques for collecting granulocytes for transfusion either to neutropenic patients or to neonates are described. Currently, the best granulocyte concentrates are prepared using continuous-flow centrifugation leukapheresis of steroid-stimulated donors in the presence of pentastarch. Donor reactions are mild and are similar to those expected with automated plateletpheresis.
Strauss
R G
RG
DeGowin Blood Center, University of Iowa Hospitals and Clinics, Iowa City.
Rohret
P A
PA
Randels
M J
MJ
Winegarden
D C
DC
D005434:Flow Cytometry; D006098:Granulocytes; D006801:Humans; D007937:Leukapheresis / Q000379:methods*; D007958:Leukocyte Count; D009504:Neutrophils