title: Structure-based inhibition of HIV-1 protease activity and viral infectivity.
authors.affiliation: Department of Pharmaceutical Chemistry, University of California, San Francisco 94143-0446.
authors.forename: D L
authors.initials: DL
authors.lastname: DeCamp
authors.forename: L M
authors.initials: LM
authors.lastname: Babé
authors.forename: P
authors.initials: P
authors.lastname: Furth
authors.forename: P
authors.initials: P
authors.lastname: Ortiz de Montellano
authors.forename: I D
authors.initials: ID
authors.lastname: Kuntz
authors.forename: C S
authors.initials: CS
authors.lastname: Craik
mesh_terms: D001665:Binding Sites; D002402:Cathepsin D / Q000037:antagonists & inhibitors; D016333:HIV Protease / Q000737:chemistry; D017320:HIV Protease Inhibitors; D015497:HIV-1 / Q000187:drug effects* / Q000201:enzymology / Q000502:physiology; D006220:Haloperidol / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D015394:Molecular Structure; D011480:Protease Inhibitors / Q000494:pharmacology; D014779:Virus Replication / Q000187:drug effects; D000092502:Renin Inhibitors
chemical_list: D002402:Cathepsin D; D016333:HIV Protease; D017320:HIV Protease Inhibitors; D006220:Haloperidol; D011480:Protease Inhibitors; D000092502:Renin Inhibitors