title: Effect of chronic non-lethal doses of non-metals and metals on hepatic metallothionein in Channa punctatus (Bloch).
abstract: Compared to non-metal toxicants (ammonia, 1.56 ppm; and phenol, 10 ppm), the metals (CdCl2, 30 ppm; HgCl2, 16.7 ppb; and ZnCl2, 6 ppm) significantly induced hepatic metallothionein (MT) concentrations in C. punctatus, exposed independently to non-lethal doses of these toxicants for 28 days. It is suggested that hepatic MT serves as a metal-sequestering protein and is involved in the detoxication of metals only and ensures protection from toxic chemicals in ambience.
authors.affiliation: Environmental Toxicology Laboratory, Department of Zoology, School of Life Sciences, Visva-Bharati, Santiniketan, India.
authors.forename: R
authors.initials: R
authors.lastname: Dalal
authors.forename: S
authors.initials: S
authors.lastname: Bhattacharya
mesh_terms: D064753:Ammonium Hydroxide; D000818:Animals; D002712:Chlorides / Q000494:pharmacology*; D005399:Fishes / Q000378:metabolism*; D005786:Gene Expression Regulation / Q000187:drug effects; D006878:Hydroxides / Q000494:pharmacology*; D008099:Liver / Q000378:metabolism; D008627:Mercuric Chloride / Q000494:pharmacology*; D008668:Metallothionein / Q000096:biosynthesis*; D019800:Phenol; D010636:Phenols / Q000494:pharmacology*; D013268:Stimulation, Chemical; D015032:Zinc / Q000494:pharmacology*; D017967:Zinc Compounds
chemical_list: D002712:Chlorides; D006878:Hydroxides; D010636:Phenols; D017967:Zinc Compounds; D019800:Phenol; D064753:Ammonium Hydroxide; D008627:Mercuric Chloride; C016837:zinc chloride; D008668:Metallothionein; D015032:Zinc