title: The copper chelating agent tetraethylenepentamine inhibits copper, zinc-superoxide dismutase activity in rat liver: a possible mechanism for its hepatotoxicity.
authors.affiliation: Department of Public Health, Yamaguchi University School of Medicine, Ube, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Ishiyama
authors.forename: K
authors.initials: K
authors.lastname: Ogino
authors.forename: T
authors.initials: T
authors.lastname: Hobara
authors.forename: Y
authors.initials: Y
authors.lastname: Shimomura
authors.forename: Y
authors.initials: Y
authors.lastname: Kanbe
authors.forename: S
authors.initials: S
authors.lastname: Yamashita
mesh_terms: D000410:Alanine Transaminase / Q000378:metabolism; D000818:Animals; D002614:Chelating Agents / Q000494:pharmacology*; D056486:Chemical and Drug Induced Liver Injury; D004333:Drug Administration Routes; D005029:Ethylenediamines / Q000633:toxicity*; D005978:Glutathione / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000201:enzymology* / Q000473:pathology; D008107:Liver Diseases / Q000378:metabolism*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013482:Superoxide Dismutase / Q000037:antagonists & inhibitors*; D014266:Trientine / Q000494:pharmacology
chemical_list: D002614:Chelating Agents; D005029:Ethylenediamines; D013482:Superoxide Dismutase; D000410:Alanine Transaminase; D005978:Glutathione; D014266:Trientine; C034269:tetraethylenepentamine