title: [Wernicke-Korsakoff syndrome caused by prolonged infusion therapy during the postoperative period].
abstract: Wernicke-Korsakoff's syndrome (W.K.S.) is a complication of alcoholism and malnutrition and usually presents acutely and is characterized by disturbances of consciousness, paralysis of the external ocular muscles, ataxia and disorder of retentive memory. The disease results from deficiency of vitamin B1, or thiamine, an essential coenzyme in intermediate carbohydrate metabolism. We report a seriously ill, nonalcoholic surgical patient, who developed W.K.S. in the postoperative period as a result of thiamine deficiency, during prolonged intravenous therapy. It is recommended that malnourished patients receive 100 mg parenteral thiamine especially when glucose infusions are administered.
authors.affiliation: Divisione di Medicina generale, Ospedale Filippo Del Ponte, Varese.
authors.forename: V
authors.initials: V
authors.lastname: Ferrari
authors.forename: E
authors.initials: E
authors.lastname: Baratelli
authors.forename: C
authors.initials: C
authors.lastname: Colombo
authors.forename: L
authors.initials: L
authors.lastname: Vitaloni
authors.forename: M
authors.initials: M
authors.lastname: Broggini
mesh_terms: D000368:Aged; D000425:Alcohol Amnestic Disorder / Q000209:etiology*; D005217:Fat Emulsions, Intravenous / Q000008:administration & dosage; D005260:Female; D005440:Fluid Therapy / Q000009:adverse effects*; D042882:Gallstones / Q000601:surgery; D005947:Glucose / Q000008:administration & dosage; D006801:Humans; D011183:Postoperative Complications / Q000209:etiology*; D016717:Sphincterotomy, Endoscopic; D013832:Thiamine Deficiency / Q000209:etiology*; D013997:Time Factors; D014839:Vomiting / Q000150:complications
chemical_list: D005217:Fat Emulsions, Intravenous; D005947:Glucose
vernacular_title: Sindrome di Wernicke-Korsakoff da terapia infusionale prolungata in periodo postoperatorio.