[Consecutive observation of the plasma MDA, XO and UA levels and erythrocyte SOD in 10 cases of cardiopulmonary bypass].
The plasma malonaldehyde (MDA), xanthine oxidase (XO) and uric acid (UA) levels and erythrocyte superoxide dismutase (SOD) were measured in 10 cases during cardiopulmonary bypass (CPB) operation. These examinations were taken at pre-aortic clamping, 15 min after aortic clamping, 30, 60, 120 and 180 min after reperfusion respectively. The results showed that MDA, XO and UA rise but SOD decreases after reperfusion. We believe that a lot of oxygen free radicals (OFR) release during peri-operative period and the XO may be an important pathway of OFR release.
Xiao
X
X
Tian
Z
Z
Wu
X
X
Yin
Q
Q
Huang
X
X
Yuan
H
H
Liang
S
S
Shi
Y
Y
D002315:Cardiopulmonary Bypass; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D005609:Free Radicals / Q000378:metabolism; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008315:Malondialdehyde / Q000097:blood*; D013482:Superoxide Dismutase / Q000097:blood*; D013997:Time Factors; D014527:Uric Acid / Q000097:blood*; D014969:Xanthine Oxidase / Q000097:blood*
D005609:Free Radicals; D014527:Uric Acid; D008315:Malondialdehyde; D013482:Superoxide Dismutase; D014969:Xanthine Oxidase