[Perioperative preventive use of ciprofloxacin in patients with cancer of the larynx].
In comparative study of patients with laryngeal cancer, perioperative prophylaxis with ciprofloxacin was estimated. The drug was administered intravenously 200 mg twice daily, for five days to groups of 95 patients. Bacteriological examinations performed intraoperatively mostly revealed Gram-positive germs. The intravenous form of ciprofloxacin was very effective, resulting in complete healing of the operative wound in shorter time than in control groups. The drug has been well tolerated and no side effects were observed.
Szmeja
Z
Z
Kliniki Otolaryngologicznej Katedry Chorób Ucha, Nosa, Gardła i Krtani AM w Poznaniu.
Kulczyński
B
B
Pietkiewicz
K
K
Kwiatek
G
G
Michalska
W
W
Chylak
J
J
D001424:Bacterial Infections / Q000517:prevention & control*; D002939:Ciprofloxacin / Q000008:administration & dosage*; D006801:Humans; D007275:Injections, Intravenous; D007822:Laryngeal Neoplasms / Q000601:surgery*; D007825:Laryngectomy; D007830:Larynx / Q000187:drug effects / Q000382:microbiology / Q000601:surgery*; D011300:Preoperative Care; D013530:Surgical Wound Infection / Q000517:prevention & control*; D014945:Wound Healing / Q000187:drug effects
D002939:Ciprofloxacin
Profilaktyka okołooperacyjna z zastosowaniem ciprofloksacyny u chorych na raka krtani.