[Sympathetic regulation of heart rhythm under the effect of delta sleep peptide and its deficiency].
In acute experiments on 16 rabbits we've studied effects of delta-sleep peptide and its deficiency on the irritation of the stellate ganglion. It has been revealed, that peptide injection (60 nM/kg) produces lowered positive chronotropic effect and elongated response development during irritation of this ganglion. Administration of antiserum to delta-sleep peptide (T = 1:3000) causes opposite effect: enhances sympathetic response during irritation of the stellate ganglion. Thus, delta-sleep peptide promoted lowered sympathetic influences on the heart.
Ul'ianinskiĭ
L S
LS
Zviaginstseva
M A
MA
D000818:Animals; D003701:Delta Sleep-Inducing Peptide / Q000172:deficiency / Q000494:pharmacology / Q000502:physiology*; D004562:Electrocardiography; D006339:Heart Rate / Q000187:drug effects; D011817:Rabbits; D013233:Stellate Ganglion / Q000187:drug effects / Q000502:physiology; D013564:Sympathetic Nervous System / Q000187:drug effects / Q000502:physiology*
D003701:Delta Sleep-Inducing Peptide
Simpaticheskaia reguliatsiia serdechnogo ritma pri deĭstvii peptida del'ta-sna i ego defitsite v organizme.