Subgroup assignment of a human monoclonal anti-Rh(D) antibody.
Variable subgroups of both chains of a human monoclonal anti-RH(D) IgG1 (kappa), QA37C3G6, were determined from their N-terminal sequences. Sequence comparison with corresponding chains of other human antibodies indicated that the light chain belongs to the third subgroup of human kappa-light chains while the heavy chain belongs to the second subgroup of human heavy chains.
Dlouha
A
A
Unité de Chimie des Proteines, Institut Pasteur, Paris, France.
Lecroisey
A
A
Henschen
A
A
Rouger
P
P
Keil
B
B
D000595:Amino Acid Sequence; D000911:Antibodies, Monoclonal / Q000737:chemistry / Q000276:immunology*; D006801:Humans; D006825:Hybridomas / Q000378:metabolism; D007143:Immunoglobulin Heavy Chains / Q000737:chemistry; D007147:Immunoglobulin Light Chains / Q000737:chemistry; D008969:Molecular Sequence Data; D012204:Rh-Hr Blood-Group System / Q000276:immunology*; D014407:Tumor Cells, Cultured
D000911:Antibodies, Monoclonal; D007143:Immunoglobulin Heavy Chains; D007147:Immunoglobulin Light Chains; D012204:Rh-Hr Blood-Group System