[The influence of lipoprotein (a) in thrombolysis with r-TPA for myocardial infarction].
OBJECTIVE
To evaluate the influence of lipoprotein (a) (Lp (a)) levels in thrombolysis with rt-PA for myocardial infarction (MI).


METHODS
Thirty-eight MI patients, 28 male, mean age 51 +/- 9 years, submitted to thrombolysis with rt-PA, divided in two groups according the result of the thrombolysis: A) Successful, B) Failure. Serum fibrinogen (SF) was assessed before and 90 minutes after treatment. Lp (a) levels were determined six months later. These parameters were analyzed in both groups.


RESULTS
Lp (a) levels were similar in groups A and B (p = 0.45). The SF levels were not different in the groups.


CONCLUSIONS
Lp (a) seems to have no influence in thrombolysis with rt-PA for MI.
Santos Filho
R D
RD
Instituto do Coração do Hospital das Clínicas-FMUSP, São Paulo.
Tranchesi Júnior
B
B
Caramelli
B
B
Barbosa
V
V
Gebara
O
O
de Albuquerque
C P
CP
Vinagre
C
C
Maranhão
R
R
Pileggi
F
F
D000284:Administration, Oral; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D007275:Injections, Intravenous; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D009203:Myocardial Infarction / Q000097:blood / Q000188:drug therapy*; D011863:Radioimmunoassay; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage / Q000627:therapeutic use*
D008074:Lipoproteins; D005340:Fibrinogen; D010959:Tissue Plasminogen Activator
Influência da lipoproteína (a) na trombólise com rt-PA no infarto do miocárdio.