title: Energy requirements for the basal efflux of noradrenaline and its metabolites from adrenergic varicosities.
abstract: The combination of hypoxia plus glucose deprivation or of hypoxia plus lactate induces carrier-mediated outward transport of 3H-noradrenaline in the rat vas deferens. Lactate efflux is higher from atria than from vas deferens. Hence, the much lower contribution by outward transport to the spontaneous efflux of 3H-noradrenaline in vas deferens than atria is likely to be due to a better supply of oxygen (and perhaps also glucose) to the 3H-noradrenaline-storing varicosities in vas deferens than in atria.
authors.affiliation: Department of Pharmacology and Toxicology, University of Würzburg, Federal Republic of Germany.
authors.forename: U
authors.initials: U
authors.lastname: Trendelenburg
authors.forename: H
authors.initials: H
authors.lastname: Russ
authors.forename: E
authors.initials: E
authors.lastname: Schömig
mesh_terms: D000818:Animals; D004734:Energy Metabolism; D006019:Glycolysis; D006325:Heart Atria; D007773:Lactates / Q000378:metabolism; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism*; D010085:Oxidative Phosphorylation; D051381:Rats; D014316:Tritium; D014649:Vas Deferens / Q000294:innervation / Q000378:metabolism*
chemical_list: D007773:Lactates; D014316:Tritium; D009638:Norepinephrine