[The possible reasons for an increase in the concentration of middle-weight molecules in pathology].
Human plasma and blood were treated by kaolin, thromboplastin, streptokinase, phytohemagglutinin, hydrogen peroxide, and Fe2+. An increase in the amount of median-mass substances was found after incubation. The obtained data showed that activation of limited proteolysis, immunity, and peroxidation could be the cause of increase of median-mass substances in pathological conditions.
Chalenko
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D000937:Antigen-Antibody Reactions / Q000187:drug effects; D006801:Humans; D066298:In Vitro Techniques; D015227:Lipid Peroxidation / Q000187:drug effects; D046911:Macromolecular Substances; D008970:Molecular Weight; D010447:Peptide Hydrolases / Q000494:pharmacology; D010455:Peptides / Q000097:blood* / Q000187:drug effects
D046911:Macromolecular Substances; D010455:Peptides; D010447:Peptide Hydrolases
Vozmozhnye prichiny povysheniia kontsentratsii molekul sredneĭ massy pri patologii.