title: Maximum likelihood training of connectionist models: comparison with least squares back-propagation and logistic regression.
abstract: This paper presents maximum likelihood back-propagation (ML-BP), an approach to training neural networks. The widely reported original approach uses least squares back-propagation (LS-BP), minimizing the sum of squared errors (SSE). Unfortunately, least squares estimation does not give a maximum likelihood (ML) estimate of the weights in the network. Logistic regression, on the other hand, gives ML estimates for single layer linear models only. This report describes how to obtain ML estimates of the weights in a multi-layer model, and compares LS-BP to ML-BP using several examples. It shows that in many neural networks, least squares estimation gives inferior results and should be abandoned in favor of maximum likelihood estimation. Questions remain about the potential uses of multi-level connectionist models in such areas as diagnostic systems and risk-stratification in outcomes research.
authors.affiliation: Biomedical Information Communication Center, Oregon Health Sciences University.
authors.forename: K A
authors.initials: KA
authors.lastname: Spackman
mesh_terms: D003936:Diagnosis, Computer-Assisted; D016018:Least-Squares Analysis; D016013:Likelihood Functions; D016015:Logistic Models; D008432:Mathematical Computing; D016571:Neural Networks, Computer; D017063:Outcome Assessment, Health Care