title: Fluoride-releasing core build-up materials and artificial caries.
abstract: This study examined the effect of fluoride-releasing core build-up materials upon both enamel and root demineralization in an artificial caries system. Thirty extracted human molars were randomly assigned to three treatment groups consisting of (1) conventional composite core build-up paste, (2) fluoridated core build-up paste and (3) glass cermet. Teeth were thermocycled 350 times between 5 degrees C and 55 degrees C using 30-second dwell times. Acid-resistant varnish was placed on the specimens to within 1 mm of the restoration and the teeth were subjected to an artificial-caries challenge at pH 4.2 for 72 hours. Teeth were then sectioned and the thin sections photographed using a polarized light microscope. Areas of the artificial-caries lesions were measured using a sonic digitizing pad. Mean lesion area (in arbitrary units from the digitizing pad) on enamel for Group 1 was 3.76 +/- 0.54; Group 2 was 2.53 +/- 1.17 and Group 3 was 2.32 +/- 0.68. Mean lesion area on root for Group 1 was 3.04 +/- 0.54; Group 2 was 2.34 +/- 0.58 and Group 3 was 2.51 +/- 0.53. ANOVA with Duncan's multiple range test of contrast indicates a significant difference (P less than 0.001) on both enamel (35 +/- 3%) and root (20 +/- 3%) between the non-fluoridated product and the two fluoridated products. There were no significant differences between Group 2 and 3.
  
  
  CONCLUSIONS
  This artificial caries study indicates that a fluoride-releasing core material may be of value in preventing demineralization of tooth structure adjacent to the restorative core material.
authors.affiliation: Center for Clinical Studies, College of Dentistry, University of Iowa, Iowa City 52242.
authors.forename: P T
authors.initials: PT
authors.lastname: Triolo
authors.forename: J S
authors.initials: JS
authors.lastname: Wefel
authors.forename: M E
authors.initials: ME
authors.lastname: Jensen
mesh_terms: D000704:Analysis of Variance; D016722:Cermet Cements; D003188:Composite Resins; D003692:Delayed-Action Preparations; D003731:Dental Caries / Q000517:prevention & control*; D003793:Dental Restoration, Permanent; D005460:Fluorides, Topical / Q000008:administration & dosage*; D006801:Humans
chemical_list: D016722:Cermet Cements; D003188:Composite Resins; C074317:Core Paste composite resin; D003692:Delayed-Action Preparations; D005460:Fluorides, Topical; C074316:FluoroCore