Hepatoprotector effect of Chrysanthemum balsamita extract in ethanol intoxicated rats.
Male Wistar rats weighing 200 +/- 10 g were intoxicated with ethanol 50% (1 ml/100 g b.w./, day, for 12 days) and concomitantly treated with hydroethanol extract of Chrysanthemum balsamita. An increase of liver glucose-6-phosphatase and phosphorylase a activities correlated with a liver glycogen breakdown as well as a decrease of glycemia were obtained in rats given ethanol 50%. It was found that Chrysanthemum balsamita extract counteracted ethanol effects and maintained at normal limit the metabolite parameters.
Coprean
D
D
Biological Research Institute, Cluj-Napoca, Romania.
Giurgea
R
R
Rusu
M
M
Tamaş
M
M
D000435:Alcoholic Intoxication / Q000188:drug therapy*; D000818:Animals; D006519:Hepatitis, Alcoholic / Q000201:enzymology / Q000517:prevention & control*; D008112:Liver Glycogen / Q000378:metabolism; D008297:Male; D010936:Plant Extracts / Q000627:therapeutic use*; D051381:Rats; D011919:Rats, Inbred Strains
D008112:Liver Glycogen; D010936:Plant Extracts