Immunodiagnosis of schistosomiasis. Screen with FAST-ELISA and confirm with immunoblot.
The most efficacious and practical means of diagnosing human schistosomiasis is based on the detection of infection-specific antibodies. Because of their high sensitivity, antibody assays remain the most practical assays for epidemiologic studies and patient management. Initial screening may be performed in the field or laboratory with the FAST-ELISA, using adult microsomal antigens. Species-specific confirmation is obtained by immunoblots with the same antigens.
Tsang
V C
VC
Parasitic Diseases Branch, Centers for Disease Control, Atlanta, Georgia.
Wilkins
P P
PP
D015153:Blotting, Western; D003365:Costs and Cost Analysis; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006801:Humans; D007159:Immunologic Tests / Q000379:methods*; D011933:Reagent Kits, Diagnostic; D012552:Schistosomiasis / Q000175:diagnosis*; D012680:Sensitivity and Specificity
D011933:Reagent Kits, Diagnostic