NSAIDs, musculoskeletal disorders and gastrointestinal adverse effects.
Paracetamol should be considered as first line treatment for the common painful musculoskeletal disorders, especially osteoarthrosis. NSAIDs, which are beneficial should this fail and inflammation be present, should be prescribed in the lowest dose for the shortest possible time.
Day
R
R
School of Physiology and Pharmacology, University of New South Wales.
Seideman
P
P
D000082:Acetaminophen / Q000627:therapeutic use; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001847:Bone Diseases / Q000188:drug therapy*; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced* / Q000517:prevention & control; D005938:Glucocorticoids / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D009135:Muscular Diseases / Q000188:drug therapy*; D009294:Narcotics / Q000627:therapeutic use; D010146:Pain / Q000188:drug therapy; D010437:Peptic Ulcer / Q000150:complications / Q000517:prevention & control
D000894:Anti-Inflammatory Agents, Non-Steroidal; D005938:Glucocorticoids; D009294:Narcotics; D000082:Acetaminophen