title: Synthesis and anti-peptic activity of compounds related to the metabolites of sodium 3-ethyl-7-isopropyl-1-azulenesulfonate (KT1-32).
abstract: The metabolites of sodium 3-ethyl-7-isopropyl-1-azulenesulfonate (KT1-32, 1), a candidate as an anti-ulcer drug, and related compounds were synthesized. The effects of the compounds on anti-peptic activity were determined as compared to that of 1.
authors.affiliation: Kotobuki Seiyaku Co., Ltd., Nagano, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yanagisawa
authors.forename: K
authors.initials: K
authors.lastname: Kosakai
authors.forename: C
authors.initials: C
authors.lastname: Izawa
authors.forename: T
authors.initials: T
authors.lastname: Tomiyama
authors.forename: M
authors.initials: M
authors.lastname: Yasunami
mesh_terms: D000897:Anti-Ulcer Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D052176:Azulenes; D012717:Sesquiterpenes / Q000737:chemistry* / Q000378:metabolism* / Q000494:pharmacology
chemical_list: D000897:Anti-Ulcer Agents; D052176:Azulenes; D012717:Sesquiterpenes; C061956:azuletil