[Isoprenoide pathway and cell proliferation in the yeast Saccharomyces cerevisiae].
Yeast mutants blocked in farnesyl diphosphate (FPP) synthetase have been isolated. Their specific phenotype is likely linked to a lowering in the FPP pool required for protein prenylation. The structural gene of FPP synthetase has been isolated. Complete inactivation of FPP synthetase by gene disruption is letal for the yeast cells.
Blanchard
L
L
Laboratoire de Biochimie et Génétique des Microorganismes, Université de Poitiers, France.
Chambon
C
C
Marcireau
C
C
Karst
F
F
D002455:Cell Division; D004122:Dimethylallyltranstransferase / Q000235:genetics / Q000378:metabolism*; D009154:Mutation / Q000235:genetics; D010641:Phenotype; D012441:Saccharomyces cerevisiae / Q000166:cytology / Q000201:enzymology* / Q000235:genetics
D004122:Dimethylallyltranstransferase
Voie des isoprénoïdes et prolifération cellulaire chez la levure Saccharomyces cerevisiae.