title: Endoscopic resection of carcinoma in situ of the esophagus accompanied by esophageal varices.
abstract: A case of carcinoma in situ of the esophagus accompanied by esophageal varices was treated by endoscopic mucosal resection using a transparent tube (EMRT) following eradication of the varices via injection sclerotherapy (EIS). Intravariceal injection sclerotherapy was performed for esophageal varices, and after eradication of the varices had been achieved, half of the circumferential esophageal mucosal resection of the cancer lesion was carried out. No serious complication such as perforation or mass bleeding was observed. Cancer-involved mucosa was completely resected and all specimens contributed well to accurate histopathological study, being diagnosed as intraepithelial squamous-cell carcinoma. The artificial ulcer recovered completely, showing no stenotic changes. Our conclusion from this experience is that EIS + EMRT is a valuable and minimally invasive treatment for patients exhibiting this disease, providing an accurate histological diagnosis.
authors.affiliation: First Department of Surgery, Tokyo Medical and Dental University, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Inoue
authors.forename: M
authors.initials: M
authors.lastname: Endo
authors.forename: K
authors.initials: K
authors.lastname: Takeshita
authors.forename: K
authors.initials: K
authors.lastname: Shimoju
authors.forename: K
authors.initials: K
authors.lastname: Yoshino
authors.forename: N
authors.initials: N
authors.lastname: Goseki
authors.forename: M
authors.initials: M
authors.lastname: Sasabe
mesh_terms: D000368:Aged; D002278:Carcinoma in Situ / Q000150:complications / Q000473:pathology / Q000601:surgery*; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000150:complications / Q000473:pathology / Q000601:surgery*; D004932:Esophageal and Gastric Varices / Q000150:complications / Q000628:therapy*; D004945:Esophagoscopy; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D009092:Mucous Membrane / Q000601:surgery; D009367:Neoplasm Staging; D015911:Sclerotherapy