Comparative study of four over-the-counter mouthrinses claiming antiplaque and/or antigingivitis benefits.
The efficacy of over-the-counter mouthrinses claiming to have antiplaque/antigingivitis benefits was compared using the modified Löe-Silness Gingival Index and the Quigley-Hein Plaque Index. The double-blind in vivo study involved 122 subjects. Each subject was randomly assigned to one of five groups. Gingival inflammation and plaque were evaluated at 0, 2, 4 and 6 weeks of product use. Results revealed that plaque scores for some of the products were statistically significant from the control at the 4-week and 6-week visits. Changes in the gingival scores were negligible.
Nelson
R F
RF
Department of Dental Hygiene, University of South Dakota, Vermillion.
Rodasti
P C
PC
Tichnor
A
A
Lio
Y L
YL
D000293:Adolescent; D000328:Adult; D000470:Alkaloids / Q000627:therapeutic use; D001565:Benzoates / Q000627:therapeutic use; D053119:Benzophenanthridines; D002594:Cetylpyridinium / Q000627:therapeutic use; D003773:Dental Plaque / Q000517:prevention & control*; D003774:Dental Plaque Index; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D005891:Gingivitis / Q000517:prevention & control*; D006801:Humans; D007546:Isoquinolines; D008297:Male; D008875:Middle Aged; D009067:Mouthwashes / Q000627:therapeutic use*; D010512:Periodontal Index; D012459:Salicylates / Q000627:therapeutic use; D012967:Sodium Dodecyl Sulfate / Q000627:therapeutic use; D013729:Terpenes / Q000627:therapeutic use
D000470:Alkaloids; D001565:Benzoates; D053119:Benzophenanthridines; D004338:Drug Combinations; D007546:Isoquinolines; D009067:Mouthwashes; C070868:Plax; D012459:Salicylates; D013729:Terpenes; D012967:Sodium Dodecyl Sulfate; C057473:Listerine; C005705:sanguinarine; D002594:Cetylpyridinium