title: [Lethal activity of benzamido-2 nitro-5 thiazole and its derivatives against Lymnaea peregra ovata Müller (Mollusca: Pulmonata) and Gammarus pulex pulex L. (Crustacea: Amphipoda)].
abstract: The toxicity of benzamido-2-nitro-5-thiazole (BNT) and 3 derivatives was studied on Lymnaea peregra ovata and Gammarus pulex pulex. These results were compared with the toxicity obtained by application of a basic product, niclosamide. The evaluation of LC50 (50% lethality concentration) was studied to evaluate the toxicity of each product after 4 different assay periods: 24, 48, 72 and 96 h. The compounds had a high toxicity against snails. Molluscicidal effect was higher than the lethal activity against Crustacea. The ortho substitution decreased the toxicity of products compared with BNT.
authors.affiliation: Faculté de pharmacie, laboratoire de parasitologie, Limoges, France.
authors.forename: P
authors.initials: P
authors.lastname: Vignoles
authors.forename: G
authors.initials: G
authors.lastname: Dreyfuss
authors.forename: D
authors.initials: D
authors.lastname: Rondelaud
mesh_terms: D000818:Animals; D003445:Crustacea; D007928:Lethal Dose 50; D008195:Lymnaea; D008975:Molluscacides; D009534:Niclosamide; D010575:Pesticides; D013844:Thiazoles
chemical_list: D008975:Molluscacides; D010575:Pesticides; D013844:Thiazoles; C074135:benzamido-2-nitro-5-thiazole; D009534:Niclosamide
vernacular_title: Activité létale du benzamido-2 nitro-5 thiazole et de ses dérivés sur Lymnaea peregra ovata Müller (Mollusque pulmoné) et Gammarus pulex pulex L (Crustacé amphipode).