Maternal cigarette smoking and the risk of tubal pregnancy.
The association between maternal smoking and the occurrence of tubal pregnancy was evaluated in a population-based case-control study of members of the Group Health Cooperative of Puget Sound, Seattle, Washington. Women hospitalized with tubal pregnancy from October 1981 through September 1986 (n = 274) were compared with reproductive-age women who were at risk of becoming pregnant during the same time period (n = 727). The relative risk of tubal pregnancy associated with ever having smoked cigarettes was 1.3 (95% confidence interval (CI) 1.0-1.8). Compared with women who had never smoked, those who smoked at the time of conception had a 40% increase in the risk of tubal pregnancy (95% CI 1.0-2.0). These results support earlier epidemiologic and nonepidemiologic reports of a greater risk of tubal pregnancy associated with current or recent maternal cigarette smoking.
Stergachis
A
A
Department of Pharmacy Practice, School of Pharmacy, University of Washington, Seattle 98195.
Scholes
D
D
Daling
J R
JR
Weiss
N S
NS
Chu
J
J
D016022:Case-Control Studies; D005260:Female; D006801:Humans; D011247:Pregnancy; D011274:Pregnancy, Tubal / Q000453:epidemiology / Q000209:etiology*; D011295:Prenatal Care / Q000458:organization & administration; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects* / Q000453:epidemiology