title: Serological survey for Lyme disease in sika deer (Cervus nippon yesoensis) by enzyme-linked immunosorbent assay (ELISA).
abstract: Seventy-six wild sika deer (Cervus nippon yesoensis) from areas endemic for Borrelia burgdorferi during 1988 to 1989 had the IgG antibody to the bacteria in enzyme-linked immunosorbent assay. The percentage of seropositive deer was 25.0% to strain HO14 and 22.4% to strain HP3, respectively. Specific IgG antibody titers were high in summer but low in winter. In summer, seropositive deer were 75.0%. Similar results were obtained in serum specimens obtained monthly from 4 farmed deer. It was suggested that the sika deer could be one of the wild reservoirs for B. burgdorferi in Hokkaido, Japan. The transmission risk of B. burgdorferi is considered to be greatest during late spring to early summer.
authors.affiliation: Department of Preventative Dentistry, Higashi Nippon Gakuen University, Hokkaido, Japan.
authors.forename: E
authors.initials: E
authors.lastname: Isogai
authors.forename: H
authors.initials: H
authors.lastname: Isogai
authors.forename: T
authors.initials: T
authors.lastname: Masuzawa
authors.forename: Y
authors.initials: Y
authors.lastname: Yanagihara
authors.forename: N
authors.initials: N
authors.lastname: Sato
authors.forename: S
authors.initials: S
authors.lastname: Hayashi
authors.forename: T
authors.initials: T
authors.lastname: Maki
authors.forename: M
authors.initials: M
authors.lastname: Mori
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D015748:Borrelia burgdorferi Group / Q000276:immunology / Q000472:pathogenicity*; D003670:Deer / Q000382:microbiology*; D004797:Enzyme-Linked Immunosorbent Assay; D006306:Health Surveys; D007564:Japan / Q000453:epidemiology; D008193:Lyme Disease / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology / Q000635:transmission; D012621:Seasons; D012698:Serologic Tests; D013997:Time Factors
chemical_list: D000907:Antibodies, Bacterial