[Anti-inflammatory activities and effect of rhizoma Alismatis on immune system].
10 and 20 g/kg ig of Rhizoma Alismatis (RA) markedly decrease the clearance rate of charcoal particles in mice, but have no significant effect on the weight of immune organs, or on the content of serum antibody hemolysin and immunoglobulin G and the delayed footpad edema induced by sheep red blood cell. The contact dermatitis of mouse pinnae immunized with dinitrochlorobenzene is inhibited by RA when it is given before challenge. In addition, RA 20g/kg suppresses the swelling of mouse rinnae induced by xylene and the proliferation of granuloma induced by cotton-pellet in rats. However, the content of vitamin C in the adrenal of rats is not clearly affected by RA.
Dai
Y
Y
China Pharmaceutical University, Nanjing.
Hang
B
B
Huang
Z
Z
Li
P
P
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology* / Q000627:therapeutic use; D002244:Carbon / Q000493:pharmacokinetics; D003877:Dermatitis, Contact / Q000517:prevention & control*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology* / Q000627:therapeutic use; D006968:Hypersensitivity, Delayed / Q000276:immunology; D008657:Metabolic Clearance Rate / Q000187:drug effects; D051379:Mice
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004365:Drugs, Chinese Herbal; D002244:Carbon