title: Functional MR of the kidney.
abstract: A bolus injection of Gadopentetate Dimeglumine with dynamic gradient echo MR imaging has allowed for the visualization of normal and abnormal renal function. Following an injection of gadopentetate dimeglumine, NMR T1 relaxation times obtained on serial collections of serum and urine at timed intervals were used to derive the glomerular filtration rate. The merger of dynamic contrast-enhanced MRI with an in vitro NMR-derived GFR provides for assessment of renal function without the use of radioactive agents.
authors.affiliation: Diagnostic Radiology Department, Warren Grant Magnuson Clinical Center, National Institutes of Health, Bethesda, Maryland 20892.
authors.forename: J A
authors.initials: JA
authors.lastname: Frank
authors.forename: P L
authors.initials: PL
authors.lastname: Choyke
authors.forename: H A
authors.initials: HA
authors.lastname: Austin
authors.forename: M E
authors.initials: ME
authors.lastname: Girton
mesh_terms: D000818:Animals; D005682:Gadolinium; D019786:Gadolinium DTPA; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000033:anatomy & histology* / Q000502:physiology; D007674:Kidney Diseases / Q000175:diagnosis*; D007677:Kidney Function Tests; D008279:Magnetic Resonance Imaging; D009942:Organometallic Compounds; D004369:Pentetic Acid
chemical_list: D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA