title: Biochemical thyroid profile in patients infected with the human immunodeficiency virus.
abstract: Over a 2-year period, thyroid function was studied in 102 patients infected with the human immunodeficiency virus (HIV) and in 102 age- and sex-matched controls with various infectious diseases. Biochemical abnormalities were observed in 1-20% of the patients, depending on thyroid indices, but thyroid disease (hypothyroidism) was diagnosed in only 1. Compared to controls, patients, especially those with the acquired immunodeficiency syndrome (AIDS), had a significant increase in serum thyroxine-binding globulin, a lower T3 and free thyroxine index, and a higher frequency of thyroglobulin antibodies.
authors.affiliation: Laboratory of Experimental Medicine, Saint Pierre University Hospital, Brussels, Belgium.
authors.forename: P P
authors.initials: PP
authors.lastname: Bourdoux
authors.forename: S A
authors.initials: SA
authors.lastname: De Wit
authors.forename: G M
authors.initials: GM
authors.lastname: Servais
authors.forename: N
authors.initials: N
authors.lastname: Clumeck
authors.forename: M A
authors.initials: MA
authors.lastname: Bonnyns
mesh_terms: D000328:Adult; D000368:Aged; D000906:Antibodies / Q000032:analysis / Q000276:immunology; D005260:Female; D015658:HIV Infections / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013954:Thyroglobulin / Q000276:immunology; D013961:Thyroid Gland / Q000276:immunology / Q000378:metabolism / Q000502:physiology*; D013974:Thyroxine / Q000097:blood; D013975:Thyroxine-Binding Proteins / Q000378:metabolism; D014284:Triiodothyronine / Q000097:blood
chemical_list: D000906:Antibodies; D013975:Thyroxine-Binding Proteins; D014284:Triiodothyronine; D013954:Thyroglobulin; D013974:Thyroxine