title: Presence of quinolone resistance in a strain of Salmonella typhimurium.
abstract: A human isolate of Salmonella typhimurium was found to be highly resistant to several antibiotics including quinolones (MIC of ciprofloxacin 16 mg/l). Killing by ciprofloxacin was only achieved after prolonged exposure to drug concentrations above the MIC. The quinolone resistance of this particular strain was not mediated by plasmids which, however, coded for several other resistance properties.
authors.affiliation: Institute of Medical Microbiology and Hygiene, Faculty of Clinical Medicine, University of Heidelberg, Klinikum Mannheim, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Hof
authors.forename: I
authors.initials: I
authors.lastname: Ehrhard
authors.forename: H
authors.initials: H
authors.lastname: Tschäpe
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D002648:Child; D002939:Ciprofloxacin / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D012480:Salmonella Infections / Q000382:microbiology; D012486:Salmonella typhimurium / Q000187:drug effects* / Q000302:isolation & purification; D013045:Species Specificity
chemical_list: D000890:Anti-Infective Agents; D002939:Ciprofloxacin