[The action of xanthinol nicotinate on the central and peripheral arterial pressure and on respiration in dogs].
The pharmaceutical trial in dogs on the influence the Romanian pharmaceutical product xanthinol nicotinate has on the cardiovascular system (central and peripheric blood pressure, venous pressure, EKG) and respiratory system rendered evident a hypotensive effect in direct ratio to the dose, prevalently peripheric, without significant changes in respiratory amplitude. It is concluded that the Romanian product has similar effects to those described in the literature for xanthinol nicotinate.
Mungiu
O C
OC
Universitatea de Medicină şi Farmacie Iaşi.
Topoliceanu
F
F
Ionescu
G D
GD
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D005260:Female; D008297:Male; D012119:Respiration / Q000187:drug effects*; D014971:Xanthinol Niacinate / Q000494:pharmacology*
D014971:Xanthinol Niacinate
Acţiunea xantinolului nicotinat asupra tensiunii arteriale centrale şi periferice şi asupra respiraţiei la cîine.