title: [Variability of the response to recombinant human erythropoietin in patients undergoing hemodialysis treatment].
abstract: The paper assesses the existence of possible interference between dialysis and the response to human recombinant erythropoietin administered i.v. in a group of patients undergoing regular dialysis. The results obtained show that the time taken to reach the set hemoglobin target (Hb 10 g%) was shorter in hemodiafiltered (HDF) patients compared to those receiving bicarbonate dialysis (BD). A plausible explantation may be the different depurative characteristics and the greater degree of biocompatibility of alternative dialysis which is able to achieve a more rapid cellular response to pharmacological stimulation.
authors.affiliation: Divisione Nefrologia, Ospedale SS. Trinità, Borgomanero, Novara.
authors.forename: A
authors.initials: A
authors.lastname: Baroni
authors.forename: G
authors.initials: G
authors.lastname: Airoldi
authors.forename: S
authors.initials: S
authors.lastname: Agliata
authors.forename: F
authors.initials: F
authors.lastname: Fortina
authors.forename: E
authors.initials: E
authors.lastname: Ragazzoni
authors.forename: A
authors.initials: A
authors.lastname: Cavagnino
authors.forename: A
authors.initials: A
authors.lastname: De Nigris
authors.forename: G
authors.initials: G
authors.lastname: Cametti
authors.forename: D
authors.initials: D
authors.lastname: Ferrero
authors.forename: A
authors.initials: A
authors.lastname: Fortina
mesh_terms: D000328:Adult; D000368:Aged; D000740:Anemia / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D001853:Bone Marrow / Q000473:pathology; D015672:Erythroid Precursor Cells / Q000473:pathology; D004921:Erythropoietin / Q000627:therapeutic use*; D005260:Female; D006440:Hemofiltration; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use*; D007231:Infant, Newborn; D007676:Kidney Failure, Chronic / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011993:Recombinant Fusion Proteins / Q000627:therapeutic use; D006435:Renal Dialysis
chemical_list: D007155:Immunologic Factors; D011993:Recombinant Fusion Proteins; D004921:Erythropoietin
vernacular_title: Variabilità di risposta all'eritropoietina umana ricombinante nei pazienti in trattamento emodialitico.