[Kinetic fibrinogen determination with batroxobin (reptilase)].
A kinetic turbidity-producing method for fibrinogen determination on the basis of reptilase reagent (batroxobin) is described. The method, which is in good agreement with method by Clauss shows comparable precision, is marked out by the possibility of objective photometric measurement. Reagent stability, use of undiluted test plasma and single-point calibration are further advantages. The method is insensitive to heparin. With regards to FDP it is less disturbed than the method by Clauss. In case of adaptation to a modern photometer a clear rationalization effect can be achieved.
Kätzel
R
R
Abteilung Transfusionsmedizin und klinische Hämostaseologie, Städtischen Klinikums St. Georg Leipzig.
Lutze
G
G
Selle
B
B
Gutwasser
H
H
D012103:Batroxobin; D004305:Dose-Response Relationship, Drug; D005340:Fibrinogen / Q000032:analysis*; D006493:Heparin / Q000494:pharmacology; D006801:Humans; D009391:Nephelometry and Turbidimetry / Q000379:methods*; D012016:Reference Values
D005340:Fibrinogen; D006493:Heparin; D012103:Batroxobin
Kinetische Fibrinogenbestimmung mit Batroxobin (Reptilase).