title: Effect of dentifrices containing either xylitol and glycerol or sorbitol on mutans streptococci in saliva.
abstract: In 76 adults, randomly distributed between two groups, a comparison was made of the effect on the level of mutans streptococci in saliva between two dentifrices containing: (1) xylitol (9.9%) and glycerol (20%) or (2) sorbitol (28%) as humectants. After the use of the dentifrices twice daily for 3 months, the levels of mutans streptococci had not changed significantly in the sorbitol-treated group, whereas a significant reduction (p less than 0.0005) was found in subjects using the xylitol/glycerol dentifrice. The difference between the two dentifrice groups based on the changes observed during the 3-month period was also significant (p less than 0.02).
authors.affiliation: Department of Public Dental Health, Kronoberg County Council, Växjö, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: Svanberg
authors.forename: D
authors.initials: D
authors.lastname: Birkhed
mesh_terms: D000328:Adult; D015169:Colony Count, Microbial; D003802:Dentifrices / Q000032:analysis / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D005990:Glycerol / Q000032:analysis / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009067:Mouthwashes; D012463:Saliva / Q000382:microbiology*; D013012:Sorbitol / Q000032:analysis / Q000627:therapeutic use*; D013291:Streptococcus / Q000302:isolation & purification; D013295:Streptococcus mutans / Q000302:isolation & purification*; D016986:Streptococcus sobrinus / Q000302:isolation & purification*; D014993:Xylitol / Q000032:analysis / Q000627:therapeutic use*
chemical_list: D003802:Dentifrices; D009067:Mouthwashes; D013012:Sorbitol; D005990:Glycerol; D014993:Xylitol