title: [The anti-idiotypic response to the experimental administration of the inactivated or live influenza virus].
abstract: The injection of inactivated and live influenza virus into rabbits induces the formation of anti-idiotypic antibodies, appearing after anti-influenza hemagglutinins, in the blood. The presence of immune complexes antibody--anti-idiotypic antibody in the blood of the animals has been established. The booster immunization of the animals with influenza virus antigens produces a rise in the levels of both idiotypic and anti-idiotypic antibodies. The injection of autologous anti-idiotypic globulin into the primed animals ensures the induction of idiotypic and anti-idiotypic revaccinal reactions.
authors.forename: L S
authors.initials: LS
authors.lastname: Kositskaia
authors.forename: B N
authors.initials: BN
authors.lastname: Sofronov
authors.forename: M A
authors.initials: MA
authors.lastname: Bichurina
authors.forename: E A
authors.initials: EA
authors.lastname: Briantseva
authors.forename: N R
authors.initials: NR
authors.lastname: Rozaeva
authors.forename: E A
authors.initials: EA
authors.lastname: Fridman
mesh_terms: D000818:Animals; D000888:Antibodies, Anti-Idiotypic / Q000097:blood*; D000914:Antibodies, Viral / Q000097:blood*; D000936:Antigen-Antibody Complex / Q000097:blood; D003168:Complement Fixation Tests; D006385:Hemagglutination Inhibition Tests; D007114:Immunization / Q000379:methods; D007117:Immunization, Secondary / Q000379:methods; D007130:Immunoglobulin Idiotypes / Q000097:blood; D009980:Influenza A virus / Q000276:immunology*; D007252:Influenza Vaccines / Q000276:immunology*; D011817:Rabbits; D013997:Time Factors; D015164:Vaccines, Inactivated / Q000276:immunology
chemical_list: D000888:Antibodies, Anti-Idiotypic; D000914:Antibodies, Viral; D000936:Antigen-Antibody Complex; D007130:Immunoglobulin Idiotypes; D007252:Influenza Vaccines; D015164:Vaccines, Inactivated
vernacular_title: Antiidiotipicheskiĭ otvet na vvedenie inaktivirovannogo ili zhivogo virusa grippa v éksperimente.