Determination of D-lactate concentration for rapid diagnosis of bacterial infections of body fluids.
The value of determining D-lactate concentrations in body fluids for the rapid diagnosis of bacterial infections was investigated. A total of 336 body fluid samples were analyzed: 208 ascitic fluids, 57 synovial fluids, 40 cerebrospinal fluids and 32 pleural fluids. Using a cut-off value of 0.05 mM, the overall sensitivity was 0.96 and the specificity was 0.88. Therefore, the measurement of D-lactate concentration in body fluids offers a rapid (2-hour) and useful method of differentiating between infectious and non-infectious body fluid diseases.
Marcos
M A
MA
Servei de Microbiologia, Hospital Clinic de Barcelona, Spain.
Vila
J
J
Gratacos
J
J
Brancos
M A
MA
Jimenez de Anta
M T
MT
D001202:Ascitic Fluid / Q000737:chemistry; D001419:Bacteria / Q000302:isolation & purification; D001424:Bacterial Infections / Q000175:diagnosis*; D001826:Body Fluids / Q000737:chemistry*; D006801:Humans; D007773:Lactates / Q000032:analysis* / Q000134:cerebrospinal fluid; D019344:Lactic Acid; D011237:Predictive Value of Tests; D013582:Synovial Fluid / Q000737:chemistry
D007773:Lactates; D019344:Lactic Acid