Ultrastructural study of a murine model for Chediak Higashi syndrome.
The kidneys and platelets of homozygous and heterozygous Chediak-Higashi syndrome mice and normal controls were studied for electron microscopic characteristics. Morphologic features were described and discussed concerning their relevance to the clinical symptoms.
Sayyid
S H
SH
Roswell Park Cancer Institute, Buffalo, NY 14263.
Bielat
K L
KL
Mahafzah
M M
MM
Ambrus
J L
JL
D000818:Animals; D001792:Blood Platelets / Q000648:ultrastructure*; D002609:Chediak-Higashi Syndrome / Q000473:pathology*; D004195:Disease Models, Animal; D005260:Female; D007668:Kidney / Q000648:ultrastructure*; D051379:Mice; D008810:Mice, Inbred C57BL; D008854:Microscopy, Electron