title: A method to optimize the design parameters of sustained release preparations.
abstract: A procedure is proposed for optimizing the design parameters of a drug, which exhibits n-exponential disposition kinetics, intended as an oral sustained release product. The product comprises two components, an immediately available dose and a portion released at a constant rate.
authors.affiliation: Departamento de Farmacia y Tecnologia Farmaceutica, Facultad de Farmacia, U.C.M. Madrid, España.
authors.forename: R
authors.initials: R
authors.lastname: Cadorniga
authors.forename: G
authors.initials: G
authors.lastname: Frutos
authors.forename: P J
authors.initials: PJ
authors.lastname: Martin
mesh_terms: D002626:Chemistry, Pharmaceutical; D003692:Delayed-Action Preparations / Q000737:chemistry*; D008962:Models, Theoretical; D010599:Pharmacokinetics
chemical_list: D003692:Delayed-Action Preparations