title: Sequential observation of fundus changes in patients with long standing membranoproliferative glomerulonephritis type II (MPGN type II).
abstract: Specific fundus changes have been reported in patients with membranoproliferative glomerulonephritis type II (MPGN type II). We studied the clinical course of this retinopathy in four patients who all had a long follow-up with several fundus examinations. Sequential observation was indicative of a slow progression of the retinopathy. Most eyes maintained in the chronic stages a nearly normal visual acuity, and a full visual field despite the existence of marked drusen and atrophic changes. The prognosis however must be somewhat guarded, since choroidal neovascularization developed in three eyes and caused bilateral severe visual loss in one patient.
authors.affiliation: Department of Ophthalmology, K.U. Leuven, Belgium.
authors.forename: A
authors.initials: A
authors.lastname: Leys
authors.forename: Y
authors.initials: Y
authors.lastname: Vanrenterghem
authors.forename: B
authors.initials: B
authors.lastname: Van Damme
authors.forename: B
authors.initials: B
authors.lastname: Snyers
authors.forename: Y
authors.initials: Y
authors.lastname: Pirson
authors.forename: M
authors.initials: M
authors.lastname: Leys
mesh_terms: D000328:Adult; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D015432:Glomerulonephritis, Membranoproliferative / Q000150:complications*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D011379:Prognosis; D012162:Retinal Degeneration / Q000473:pathology*; D015593:Retinal Drusen / Q000473:pathology; D015861:Retinal Neovascularization / Q000473:pathology; D014792:Visual Acuity