title: [Effect of dopamine on cecum motility in sheep].
abstract: The influence of dopamine on the motility of the caecum were studied. The experiments were carried out on 4 sheep with chronic fistulas of the caecum. The contractions of the caecum were recorded by the balloon method. Dopamine infused intravenously at a rate 29-38 micrograms.kg-1.min-1 inhibited the motility of the caecum. Dopamine infused after beta-adrenergic blocker propranolol (0.5-1.0 mg.kg-1) inhibited the movements of the caecum, however administrated after domperidone (0.2-0.4 mg.kg-1) didn't change its movements. It has been concluded that dopamine inhibits the caecum motility in sheep through specific dopaminergic receptors.
authors.affiliation: Katedra Fizjologii Zwierzat Wydziału Medycyny Weterynaryjnej AR, Wrocławiu.
authors.forename: D
authors.initials: D
authors.lastname: Zieba
authors.forename: T
authors.initials: T
authors.lastname: Wegrzyn
authors.forename: E
authors.initials: E
authors.lastname: Cebrat
authors.forename: Z
authors.initials: Z
authors.lastname: Leroch
mesh_terms: D000818:Animals; D002432:Cecum / Q000187:drug effects* / Q000502:physiology; D004294:Domperidone / Q000494:pharmacology; D004298:Dopamine / Q000494:pharmacology*; D004347:Drug Interactions; D005769:Gastrointestinal Motility / Q000187:drug effects*; D011433:Propranolol / Q000494:pharmacology; D011954:Receptors, Dopamine / Q000187:drug effects / Q000502:physiology; D012756:Sheep / Q000502:physiology*
chemical_list: D011954:Receptors, Dopamine; D004294:Domperidone; D011433:Propranolol; D004298:Dopamine
vernacular_title: Wpływ dopaminy na motoryke jelita ślepego u owiec.