[Role of the mucous barrier in the pathogenesis of stress ulcers of the stomach].
Using the model of immobilizing stress in rats, it has been established that the content of sialic acids in the stomach mucous membrane (SMM) and blood serum rises with simultaneous activation of proteolytic enzymes in them. The preliminary adaptation to short stressor influences parallel with an antipathogenic effect normalizes the content of sialic acids in the blood serum and SMM. The conclusion is made on the essential role of the degradation of gastric mucus in pathogenesis of stress ulcers.
Tarasenko
L M
LM
Petryshanko
T A
TA
Grebennikova
V F
VF
Skrypnik
I N
IN
D000222:Adaptation, Physiological / Q000502:physiology*; D000818:Animals; D005753:Gastric Mucosa / Q000503:physiopathology*; D010447:Peptide Hydrolases / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012149:Restraint, Physical; D012794:Sialic Acids / Q000097:blood / Q000378:metabolism*; D013276:Stomach Ulcer / Q000209:etiology / Q000503:physiopathology*; D013312:Stress, Physiological / Q000503:physiopathology*
D012794:Sialic Acids; D010447:Peptide Hydrolases
Rol' slizistogo bar'era v patogeneze stressornykh iazv zheludka.