Pump function of the heart as an optimal control problem.
In order to model the pump function of the heart the left ventricle is represented as an elastic thick-walled cylinder contracting symmetrically. The acceleration is included in the mathematical formalism describing the contraction of the myocardium and optimal control theory is used to solve the differential equation of motion of the cylindrical wall in such a way as to minimize a given performance index. Application of the equations to experimental data published in the literature is discussed. The mathematical formalism presents a new way to study the time variation of the volume ejected from the left ventricle. Methods to quantify the pump function of the heart are suggested.
Shoucri
R M
RM
Department of Mathematics and Computer Science, Royal Military College of Canada, Kingston, Ontario.
D001696:Biomechanical Phenomena; D004452:Echocardiography; D004548:Elasticity; D006321:Heart / Q000502:physiology*; D008955:Models, Cardiovascular; D009200:Myocardial Contraction; D013318:Stroke Volume / Q000502:physiology*