HLA antigens in Burger's disease.
The HLA A and B types of 20 Greek patients with thromboangiitis obliterans (TAO) were studied and compared with a panel of 400 controls. A nonstatistically significant increase in the frequencies of HLA B5, B7 and A9 antigens was found. These antigens were found to be associated with a relative risk of 3.47, 3.24 and 2.07 respectively. These findings are partially in agreement with those of a joint English-Swiss study which also found a negative association with B12 antigens; in the Greek population, also of European origin, a negative association was observed with the B8 antigen.
Zervas
J
J
Department of Internal Medicine, Athens University Medical School, Laikon General Hospital, Greece.
Vayopoulos
G
G
Konstantopoulos
K
K
Zervas
C
C
Liapis
C
C
Kaklamanis
P
P
Sechas
M
M
D000293:Adolescent; D000328:Adult; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D015234:HLA-A Antigens / Q000032:analysis; D015235:HLA-B Antigens / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012307:Risk Factors; D013919:Thromboangiitis Obliterans / Q000276:immunology*
D006680:HLA Antigens; D015234:HLA-A Antigens; D015235:HLA-B Antigens