Dieting and pain sensitivity: a validation of clinical findings.
To validate findings of a reduced pain sensitivity in anorexia and bulimia nervosa, the effects of dieting on somatosensation (especially pain sensitivity) were investigated in healthy young women. One group of subjects (n = 11) received a calorically reduced balanced diet for 21 days, while the other group (n = 14) continued to eat normally. The fasting state induced in the dieting subjects was comparable to that of eating disorder patients, since the dieters showed a reduction of the body mass index, a decrease in triiodothyronine and an increase in beta-hydroxybutyric acid plasma levels. However, neither the thresholds of pain, warmth, cold and vibration sensitivity nor the peripheral skin temperature changed systematically under the diet. Therefore, the reduced pain sensitivity in eating disorder patients is apparently not a mere effect of fasting, but a true pathological feature.
Lautenbacher
S
S
Max Planck Institute of Psychiatry, Department of Psychiatry, Munich, Germany.
Barth
K
K
Friess
E
E
Strian
F
F
Pirke
K M
KM
Krieg
J C
JC
D020155:3-Hydroxybutyric Acid; D000328:Adult; D001835:Body Weight / Q000502:physiology; D004038:Diet, Reducing / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006885:Hydroxybutyrates / Q000097:blood; D010146:Pain / Q000503:physiopathology*; D010147:Pain Measurement; D012881:Skin Temperature / Q000502:physiology; D013696:Temperature; D014284:Triiodothyronine / Q000097:blood
D006885:Hydroxybutyrates; D014284:Triiodothyronine; D020155:3-Hydroxybutyric Acid