title: [HIV infections. Problems of morphologic diagnosis].
abstract: Considerable ultrastructural changes in the lymphoid cells of immunocompetent organs as well as in the epithelial and stromal cells of the rectum--the organ of the first contact with the virus in some cases--are found in HIV-infection. These alterations are of a quantitative nature and are the indications of important disturbances of the water-salt and protein metabolism. Changes in the lymphocytes and plasmacytes of the rectum lamina propria result in the damage to local immune defense. The presence of tubuloreticular and tubulo-annular structures in various cells of the rectum and lymphoid organs which are clearly seen in the biopsy material is most likely a characteristic sign of HIV-infection at its terminal stage.
authors.forename: Iu G
authors.initials: IuG
authors.lastname: Parkhomenko
authors.forename: T G
authors.initials: TG
authors.lastname: Barkhina
mesh_terms: D000328:Adult; D004727:Endothelium / Q000648:ultrastructure*; D004848:Epithelium / Q000648:ultrastructure; D015658:HIV Infections / Q000473:pathology*; D006801:Humans; D008221:Lymphoid Tissue / Q000648:ultrastructure*; D008297:Male; D012007:Rectum / Q000648:ultrastructure*
vernacular_title: VICh-infektsiia. Problemy morfologicheskoĭ diagnostiki.