title: [Comparative studies of toothpastes and toothpaste ingredients in biological systems. 2. Study of toothpaste ingredients and their effects on cell growth].
abstract: The influence on cell growth by different ingredients of toothpastes was examined in cell culture. Following parameters were evaluated: protein concentration, MTT-test and cell morphology. Substantial inhibition of cell growth was caused by tensides. Preparations with Tego-Betain had a significantly less influence on cell growth than Texapon. Other ingredients as medical soap, fluoride and preservative showed a very low effect.
authors.affiliation: Abt. Parodontologie, Universität Gottingen.
authors.forename: B
authors.initials: B
authors.lastname: Gerckens
authors.forename: G
authors.initials: G
authors.lastname: Eisinger
authors.forename: W
authors.initials: W
authors.lastname: Krüger
mesh_terms: D000818:Animals; D001622:Betaine / Q000031:analogs & derivatives* / Q000633:toxicity; D002455:Cell Division / Q000187:drug effects*; D002478:Cells, Cultured; D005347:Fibroblasts / Q000187:drug effects; D005460:Fluorides, Topical; D006131:Growth Inhibitors; D051379:Mice; D012967:Sodium Dodecyl Sulfate / Q000633:toxicity*; D013501:Surface-Active Agents / Q000633:toxicity*; D014100:Toothpastes / Q000633:toxicity*
chemical_list: D005460:Fluorides, Topical; D006131:Growth Inhibitors; D013501:Surface-Active Agents; D014100:Toothpastes; C075204:Texapon; D012967:Sodium Dodecyl Sulfate; D001622:Betaine; C065099:Tego-Betain
vernacular_title: Vergleichende Untersuchungen von Zahnpasten und Zahnpasten-Bestandteilen in biologischen Systemen: 2. Untersuchungen von Zahnpasten-Bestandteilen auf ihre zellwachstumsbeeinflussende Wirkung.