[The effect of butylcaptax on oxidative phosphorylation and the activity of multienzyme systems of the mitochondrial membranes in the rat liver].
The oxidative phosphorylation and the activity of polyenzymatic systems in the rat liver mitochondrial membranes were studied upon a 5 day administration to rats of butylcaptax in the dose of 1/10 LD50. It is established that butylcaptax led to significant disturbances in the system of oxidative phosphorylation and in the transfer of electrons in the rat liver mitochondrial respiratory chain.
Mirakhmedov
A K
AK
Rustamov
R D
RD
Almatov
K T
KT
Agzamov
Kh
Kh
D000818:Animals; D052160:Benzothiazoles; D003678:Defoliants, Chemical / Q000494:pharmacology*; D003864:Depression, Chemical; D004789:Enzyme Activation / Q000187:drug effects; D007425:Intracellular Membranes / Q000187:drug effects* / Q000201:enzymology; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008297:Male; D008930:Mitochondria, Liver / Q000187:drug effects* / Q000201:enzymology; D010085:Oxidative Phosphorylation / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains; D013844:Thiazoles / Q000494:pharmacology*
D052160:Benzothiazoles; D003678:Defoliants, Chemical; D013844:Thiazoles; C016283:butylcaptax
Vliianie butilkaptaksa na okislitel'noe fosforilirovanie i aktivnost' polifermentnykh sistem membran mitokhondriĭ pecheni krys.