title: [The effect of immunotherapy with cell-free vaccines made from the antigens of opportunistic microorganisms on the dynamics of DNA antibody formation].
abstract: The sera of patients subjected to immunotherapy with staphylococcal vaccine and with multicomponent vaccine (i.e. the mixture of the antigenic preparations of Staphylococcus aureus, Klebsiella pneumoniae, Proteus vulgaris, Escherichia coli) were studied by the method of the enzyme immunoassay on the basis of cattle spleen DNA. Immunotherapy with staphylococcal vaccine was given to patients with dermal diseases, chronic obstructive bronchitis and pulmonary abscess. Multicomponent vaccine was introduced to patients with the infectious allergic form of bronchial asthma, moderate or severe. Immunotherapy with both preparations under study was shown to produce no accumulation of antibodies to native and denatured DNA.
authors.forename: N B
authors.initials: NB
authors.lastname: Egorova
authors.forename: N L
authors.initials: NL
authors.lastname: Shagam
authors.forename: N P
authors.initials: NP
authors.lastname: Vaneeva
authors.forename: V N
authors.initials: VN
authors.lastname: Efremova
authors.forename: G L
authors.initials: GL
authors.lastname: Osipova
authors.forename: S A
authors.initials: SA
authors.lastname: Masiukova
authors.forename: L A
authors.initials: LA
authors.lastname: Kuz'mina
mesh_terms: D000328:Adult; D001249:Asthma / Q000276:immunology / Q000628:therapy; D001323:Autoantibodies / Q000096:biosynthesis / Q000097:blood / Q000187:drug effects*; D001428:Bacterial Vaccines / Q000627:therapeutic use*; D001991:Bronchitis / Q000276:immunology / Q000628:therapy; D004247:DNA / Q000187:drug effects / Q000276:immunology*; D004338:Drug Combinations; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007114:Immunization; D007124:Immunoenzyme Techniques; D007167:Immunotherapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D013207:Staphylococcal Skin Infections / Q000276:immunology / Q000628:therapy; D015164:Vaccines, Inactivated / Q000627:therapeutic use
chemical_list: D001323:Autoantibodies; D001428:Bacterial Vaccines; D004338:Drug Combinations; D015164:Vaccines, Inactivated; D004247:DNA
vernacular_title: Izuchenie vliianiia immunoterapii beskletochnymi vaktsinami iz antigenov uslovno-patogennykh mikroorganizmov na dinamiku obrazovaniia antitel k DNK.