[The anti-idiotypic response to the experimental administration of the inactivated or live influenza virus].
The injection of inactivated and live influenza virus into rabbits induces the formation of anti-idiotypic antibodies, appearing after anti-influenza hemagglutinins, in the blood. The presence of immune complexes antibody--anti-idiotypic antibody in the blood of the animals has been established. The booster immunization of the animals with influenza virus antigens produces a rise in the levels of both idiotypic and anti-idiotypic antibodies. The injection of autologous anti-idiotypic globulin into the primed animals ensures the induction of idiotypic and anti-idiotypic revaccinal reactions.
Kositskaia
L S
LS
Sofronov
B N
BN
Bichurina
M A
MA
Briantseva
E A
EA
Rozaeva
N R
NR
Fridman
E A
EA
D000818:Animals; D000888:Antibodies, Anti-Idiotypic / Q000097:blood*; D000914:Antibodies, Viral / Q000097:blood*; D000936:Antigen-Antibody Complex / Q000097:blood; D003168:Complement Fixation Tests; D006385:Hemagglutination Inhibition Tests; D007114:Immunization / Q000379:methods; D007117:Immunization, Secondary / Q000379:methods; D007130:Immunoglobulin Idiotypes / Q000097:blood; D009980:Influenza A virus / Q000276:immunology*; D007252:Influenza Vaccines / Q000276:immunology*; D011817:Rabbits; D013997:Time Factors; D015164:Vaccines, Inactivated / Q000276:immunology
D000888:Antibodies, Anti-Idiotypic; D000914:Antibodies, Viral; D000936:Antigen-Antibody Complex; D007130:Immunoglobulin Idiotypes; D007252:Influenza Vaccines; D015164:Vaccines, Inactivated
Antiidiotipicheskiĭ otvet na vvedenie inaktivirovannogo ili zhivogo virusa grippa v éksperimente.