title: [Psoralen sensitized thermoactivated photodamage to leukocyte membranes].
abstract: Psoralen sensitized photodamage of rat peritoneal exudate cells was investigated. Irradiation of cells induced latent lesions in membranes which during thermal activation at the post-irradiation stage were transformed into permeability channels for trypan blue. The effect linearly increased with fluence of irradiation which indicates one hit production of thermolabile psoralen photoproducts in the membranes.
authors.forename: A A
authors.initials: AA
authors.lastname: Kiagova
authors.forename: M I
authors.initials: MI
authors.lastname: Ismailova
authors.forename: A Ia
authors.initials: AIa
authors.lastname: Potapenko
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000187:drug effects / Q000528:radiation effects; D011564:Furocoumarins / Q000494:pharmacology*; D006358:Hot Temperature; D007962:Leukocytes / Q000187:drug effects* / Q000528:radiation effects; D010529:Peritoneal Cavity / Q000166:cytology; D051381:Rats; D014466:Ultraviolet Rays
chemical_list: D011564:Furocoumarins
vernacular_title: Sensibilizirovannye psoralenom termoaktiviruemye fotopovrezhdeniia membran leĭkotsitov.