[Immunohistochemical study of temporomandibular joint disturbance syndrome].
In this paper, condylar cartilages of 10 temporomandibular joint disturbance syndrome (TMJDS) patients were studied by means of immunofluorescence and immunogold staining to clarify if there are immune complexes. We also detected the antibodies to type II collagen in synovial fluids and sera of the TMJDS patients with passive hemagglutination. Through these studies, we found: there are autoimmune responses in articular tissues in TMJDS; these responses are caused by the exposure of sequestered antigens and taken place mainly in the involved joints, and may participate in the destruction of TMJ.
Gu
Z Y
ZY
School of Stomatology, Beijing Medical University.
D000328:Adult; D001323:Autoantibodies / Q000032:analysis; D003094:Collagen / Q000276:immunology; D005455:Fluorescent Antibody Technique; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008335:Mandibular Condyle; D013582:Synovial Fluid / Q000737:chemistry; D013704:Temporomandibular Joint / Q000378:metabolism*; D013706:Temporomandibular Joint Dysfunction Syndrome / Q000276:immunology / Q000378:metabolism*
D001323:Autoantibodies; D003094:Collagen