[Clinical effect of ligustrazine in patients with benign paroxysmal positional vertigo].
The therapeutic effect of Ligustrazine was studied in patients with benign paroxysmal positional vertigo (BPPV). 11 cases were given Ligustrazine 100 mg daily (iv. or im.), another 11 cases were given Valium and Diphenidol as the control group. The results were as follows: In Ligustrazine group, the average curative time was 37 days. In the control group, the average curative time was 72 days. This result suggests that Ligustrazine is a useful drug in the treatment of BPPV. It is believed that the cause of BPPV is due to the occlusion of the anterior vestibular artery. Ligustrazine has the effect of improving microcirculation of the cochlea.
Zhao
P Y
PY
First Affiliated Hospital of Beijing Medical University.
D000328:Adult; D000368:Aged; D003051:Cochlea / Q000098:blood supply; D005260:Female; D006801:Humans; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D011187:Posture; D011719:Pyrazines / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use*; D014717:Vertigo / Q000188:drug therapy* / Q000503:physiopathology
D011719:Pyrazines; D014665:Vasodilator Agents; C017953:tetramethylpyrazine