[Systemic lupus erythematosus and AIDS. Difficulties in the differential diagnosis].
AIDS and systemic lupus erythematosus (SLE) share clinical and laboratory features that may difficult a differential diagnosis. We report five patients who presented diagnostic problems, two of them with SLE diagnosis and HIV-1 false-reactive screening tests, and the other three with AIDS diagnosis and clinical features fulfilling four or more ARA-clinical criteria for the diagnosis of SLE. It is recommended that tests for HIV-1 antibodies in patients with symptoms of SLE, be carried out by at least three different methods, with direct HIV-1 antigen detection as final confirmatory technique. On the other hand, as also proposed for Sjogren syndrome, the presence of HIV-1 or its antigens, established through cell-cultures or direct blood detection, should be considered as exclusion criteria for SLE diagnosis.
Montero
A
A
Departamento de Clínica Médica, Hospital de Emergencias Dr. Clemente Alvarez, Rosario, Argentina.
Prato
R
R
Jorfen
M
M
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000175:diagnosis*; D000328:Adult; D015153:Blotting, Western; D003937:Diagnosis, Differential; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005455:Fluorescent Antibody Technique; D015483:HIV Antibodies / Q000032:analysis; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis*; D008297:Male
D015483:HIV Antibodies
Lupus eritematoso sistémico y SIDA. Dificultades en el diagnóstico diferencial.