[Severe prolonged hypotension after the first dose of enalapril in a patient with essential hypertension].
A case of severe and prolonged hypotension following intake of 10 mg enalapril in a patient with slight hyponatraemia is described. Despite administration of isotonic NaCl and treatment with dopamine infusion, it did not prove possible to maintain a stable blood pressure. Adrenaline and ephedrine were required intravenously on repeated occasions on account of symptom-producing hypotension with a systolic pressure as low as 60 mmHg. On account of the increasing use of ACE-inhibitors, it is recommended that the specific antidote, angiotension II, should be registered in Denmark and should be available in all hospitals.
Rannem
T
T
Medicinsk afdeling B., Centralsygehust Hillerød.
Eriksen
J
J
Fruergaard
P
P
D004656:Enalapril / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D007022:Hypotension / Q000139:chemically induced* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D004656:Enalapril
Svaer langvarig hypotension efter første dosis af enalapril hos en patient med essentiel hypertension.