title: [Study of neurovegetative function in type 2 diabetes mellitus in childhood].
abstract: The passive (tilting) orthoclinostatic test was performed on 44 young subjects affected by type 1 insulin-dependent diabetes. In 11 cases the test was repeated after a 3-4 years interval. The results, compared with age matched controls, showed in the diabetic patients a supersensitivity of the two antagonist systems, increasing with age and duration of the disease, up to an overexcitability and a functional exhaustion. It would thus seem that diabetic dysautonomia involves not only the peripheral nervous system but also the hypothalamic centers, with an impoverishment of the capacity of self-regulation. The hypersympathicotonus in diabetic young patients seems to be only apparent, as a result of the hypersensitivity of an overstimulated system.
authors.affiliation: Clinica Neurologica, Università di Pisa.
authors.forename: M
authors.initials: M
authors.lastname: Orsini
authors.forename: L
authors.initials: L
authors.lastname: Calisti
authors.forename: D
authors.initials: D
authors.lastname: Gandini
authors.forename: L
authors.initials: L
authors.lastname: Crespin
mesh_terms: D000293:Adolescent; D000328:Adult; D001342:Autonomic Nervous System Diseases / Q000503:physiopathology*; D002648:Child; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology*; D003929:Diabetic Neuropathies / Q000503:physiopathology*; D006339:Heart Rate; D006801:Humans; D008137:Longitudinal Studies; D011187:Posture
vernacular_title: Indagini neurovegetative nel diabete mellito tipo 1 in età pediatrica.