[An immunological study of endogenous uveitis: changes in peripheral blood T-cell subsets and their transformation rate].
Dynamic changes of peripheral blood T-cell subsets and their transformation rate were studied in 77 cases of EU. The results showed that the percentages of T3+ and T4+ cells, and the T4+/T8+ ratio decreased, while the percentage of T8+ cells increased, and the T-cell transformation rate was significantly lowered. The immunofunctional changes in chronic anterior uveitis and pan-uveitis were particularly remarkable. The findings indicated that abnormal T-cell subsets and the reduced cell-mediated immunofunction played an important role in the pathogenesis of EU.
Zhang
M D
MD
Department of Ophthalmology, Workers' General Hospital, Benxi Steel Co., Anhui Province.
Huang
S R
SR
D000293:Adolescent; D000328:Adult; D016516:CD4-CD8 Ratio; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D008213:Lymphocyte Activation; D008297:Male; D008875:Middle Aged; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D014605:Uveitis / Q000276:immunology*; D014606:Uveitis, Anterior / Q000276:immunology