Human skeletal muscle: participation of different metabolic activities in oxidation of L-lactate.
The pure mitochondrial fraction obtained from human skeletal muscle did not show coupled L-lactate (+ NAD) oxidation, but this function could be restored by addition of LDH. Thus the "direct", coupled oxidation of L-lactate described earlier (Popinigis et al., 1990. International Perspectives in Exercise Physiology, Human Kinetics Books, pp. 132-133) should be attributed to contaminations.
Popinigis
J
J
Department of Bioenergetics, Jedrzej Sniadecki Academy of Physical Education, Gdańsk-Oliwa, Poland.
Antosiewicz
J
J
Crimi
M
M
Lenaz
G
G
Wakabayashi
T
T
D004579:Electron Transport; D006801:Humans; D007773:Lactates / Q000378:metabolism*; D019344:Lactic Acid; D008928:Mitochondria / Q000378:metabolism; D009132:Muscles / Q000378:metabolism*; D010084:Oxidation-Reduction
D007773:Lactates; D019344:Lactic Acid