[Effect of immunosuppressive treatment on the crystalline lenses of patients after kidney transplantation].
Presented are the results of observation of lenses in 500 patients (aged 14-58 years, period of observation 3 months - 12 years) treated according to various schemes of immunosuppression (encorton + azathioprin, cyclosporin + encorton). One hundred and eighty patients were examined over and over again. A typical posterior subcortical cataract was detected in the course of the first examination in 25 patients, in the control one in 55. It appeared more frequently in patients who--because of the process of rejection of the kidney--received high doses of steroids (1.0 g) throughout several days. No dependence could be detected between the degree of opacity of the lens and the general doses of steroids and the period of their application.
Dróbecka-Brydakowa
E
E
Kliniki Okulistycznej AM, Warszawie, Poland.
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D001379:Azathioprine / Q000008:administration & dosage / Q000009:adverse effects*; D002386:Cataract / Q000139:chemically induced*; D016572:Cyclosporine / Q000008:administration & dosage / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D006082:Graft Enhancement, Immunologic; D006801:Humans; D007275:Injections, Intravenous; D016030:Kidney Transplantation / Q000276:immunology*; D007908:Lens, Crystalline / Q000187:drug effects*; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage / Q000009:adverse effects*; D013997:Time Factors
D016572:Cyclosporine; D001379:Azathioprine; D011241:Prednisone
Wpływ leczenia immunosupresyjnego na soczewki u chorych po przeszczepieniu nerek.