[Synthesis and biological activity of 5-phenyl-1,3,4-benzotriazepines. 25. Synthesis of (1,2,4)triazolo(4,3-a)(1,3,4)benzotriazepines and related tricyclics].
Some title compounds can be obtained conveniently by dehydration of 2-acylhydrazino- or by dehydrogenation of 2-(2-methylenhydrazino)- or by elimination of aniline from 2-phenyl(thio)semicarbazido-1,3,4-benzotriazepines. The direct cyclization of 2-hydrazino-1,3,4-benzotriazepines is not so suitable. The direction of the anellation can be elucidated by comparison of the UV spectra from compounds of known structure.
Richter
P H
PH
Fachrichtung Pharmazie, Ernst-Moritz-Arndt-Universität Greifswald.
Scheefeldt
U
U
D001552:Benzazepines / Q000138:chemical synthesis* / Q000494:pharmacology; D013056:Spectrophotometry, Ultraviolet; D014230:Triazoles / Q000138:chemical synthesis* / Q000494:pharmacology
D001552:Benzazepines; D014230:Triazoles
Synthese und biologische Aktivität von 5-phenyl-1,3,4-benzotriazepinen. 25. Mitteilung: Synthese von [1,2,4]Triazolo[4,3-a][1,3,4]benzotriazepinen und verwandten Trycyclen.