title: A current view of the interface between borderline personality disorder and depression.
abstract: The recent and dramatic expansion in studies about borderline and depressive disorders is reviewed with respect to the implications about their interface. Revisiting this subject 6 years after an earlier review reveals that intervening research has altered the conclusions that should be drawn. Growing evidence from family history, comorbidity, phenomenology, psychopharmacology, biological markers, and a new domain, pathogenesis, indicates that a surprisingly weak and nonspecific relationship exists between these disorders. Implications are drawn with respect to classification, therapeutics, and defining the borderline construct.
authors.affiliation: Personality and Psychosocial Research Program, McLean Hospital, Belmont, MA 02178.
authors.forename: J G
authors.initials: JG
authors.lastname: Gunderson
authors.forename: K A
authors.initials: KA
authors.lastname: Phillips
mesh_terms: D015415:Biomarkers; D001883:Borderline Personality Disorder / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology; D003131:Combined Modality Therapy; D015897:Comorbidity; D003866:Depressive Disorder / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology; D006801:Humans; D012701:Serotonin / Q000502:physiology
chemical_list: D015415:Biomarkers; D012701:Serotonin