title: Circadian changes in arginine vasopressin level in the suprachiasmatic nuclei in the rat.
abstract: Arginine vasopressin (AVP) neurons were preferentially localized in the dorsomedial part of the suprachiasmatic nucleus (SCN). To know the role of AVP neurons in the SCN, male rats were kept under a normal light-dark cycle (L-D), or under constant darkness (D-D) for 20 days. In L-D condition, AVP levels in the SCN showed the circadian change. In D-D condition, the patterns in AVP levels showed a free-running rhythm, and an about 12-h shift per 20 days. This result suggests that the activity of AVP neurons may be closely associated with the endogenous circadian rhythm of the SCN.
authors.affiliation: Zoological Institute, Faculty of Science, Hiroshima University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Yamase
authors.forename: S
authors.initials: S
authors.lastname: Takahashi
authors.forename: K
authors.initials: K
authors.lastname: Nomura
authors.forename: K
authors.initials: K
authors.lastname: Haruta
authors.forename: S
authors.initials: S
authors.lastname: Kawashima
mesh_terms: D000818:Animals; D001127:Arginine Vasopressin / Q000378:metabolism*; D002940:Circadian Rhythm / Q000528:radiation effects; D003345:Corticosterone / Q000097:blood; D003624:Darkness; D051381:Rats; D011919:Rats, Inbred Strains; D013493:Suprachiasmatic Nucleus / Q000378:metabolism* / Q000528:radiation effects
chemical_list: D001127:Arginine Vasopressin; D003345:Corticosterone