title: Activity of meropenem against antibiotic-resistant or infrequently encountered gram-negative bacilli.
abstract: Meropenem was compared in vitro with imipenem as well as with several other contemporary beta-lactams, ciprofloxacin, and gentamicin against a group of highly antibiotic resistant members of the family Enterobacteriaceae and a collection of oxidase-positive and/or glucose-nonfermentative gram-negative bacilli. In this study, meropenem was more active than imipenem against isolates of Enterobacter, Klebsiella, Morganella, Providencia, Alcaligenes, Aeromonas, and Pasteurella.
authors.affiliation: Department of Pathology, University of Texas Health Science Center, San Antonio 78284-7750.
authors.forename: J H
authors.initials: JH
authors.lastname: Jorgensen
authors.forename: L A
authors.initials: LA
authors.lastname: Maher
authors.forename: A W
authors.initials: AW
authors.lastname: Howell
mesh_terms: D004352:Drug Resistance, Microbial; D006090:Gram-Negative Bacteria / Q000187:drug effects*; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology; D006801:Humans; D000077731:Meropenem; D008826:Microbial Sensitivity Tests; D013845:Thienamycins / Q000494:pharmacology*
chemical_list: D013845:Thienamycins; D000077731:Meropenem