title: [The effect of the nature of the strain on the character of the production of iron-dependent proteins by meningococci].
abstract: The comparative study of three Neisseria meningitidis strains (15, 125, 2394) was carried out by the method of electrophoresis in polyacrylamide gel in the presence of sodium dodecyl sulfate and by the method of immunoblotting. The intensive expression of 8 iron-regulated proteins (IRP) was shown to occur in iron-deficient culture medium. The major IRP with a molecular weight of 35 kD was expressed by all above-mentioned N. meningitidis strains under the conditions of iron deficiency and cross-reacted with 10 mouse and rabbit antisera to N. meningitidis of different groups, i.e. it was common to all Neisseria species. The antigenic activity of various IRP essentially differed with respect to antisera of animals and sera of patients with meningococcal infection.
authors.forename: B O
authors.initials: BO
authors.lastname: Gorbacheva
authors.forename: T N
authors.initials: TN
authors.lastname: Filatova
authors.forename: A B
authors.initials: AB
authors.lastname: Petrov
mesh_terms: D000818:Animals; D001425:Bacterial Outer Membrane Proteins / Q000032:analysis / Q000096:biosynthesis* / Q000276:immunology; D001426:Bacterial Proteins; D004591:Electrophoresis, Polyacrylamide Gel; D015151:Immunoblotting; D007501:Iron / Q000032:analysis / Q000276:immunology / Q000378:metabolism*; D033862:Iron-Binding Proteins; D008585:Meningitis, Meningococcal / Q000276:immunology / Q000382:microbiology; D051379:Mice; D008970:Molecular Weight; D009345:Neisseria meningitidis / Q000737:chemistry / Q000145:classification / Q000276:immunology / Q000378:metabolism*; D033902:Periplasmic Binding Proteins; D012703:Serotyping
chemical_list: D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D033862:Iron-Binding Proteins; D033902:Periplasmic Binding Proteins; D007501:Iron
vernacular_title: Vliianie prirody shtamma na kharakter produtsirovaniia meningokokkami zhelezozavisimykh belkov.