title: [The effect of anabolic steroids on proliferative activity of thymocytes].
abstract: Testosterone, methandrostenolone during ten-day injections to mice 50 mg/kg decrease mass, quality of DNA and 3H thymidine in Thymus. In vitro these drugs loss 3H-thymidine incorporation at 10(-5) M. Ecdysthene do not influence proliferative activity of thymocytes in vitro and thymolytyc effect in vivo. The present results indicate, that proliferative process may have a functional significance in thymolytycal effects of anabolic steroids.
authors.forename: P V
authors.initials: PV
authors.lastname: Sergeev
authors.forename: A V
authors.initials: AV
authors.lastname: Semeĭkin
authors.forename: A S
authors.initials: AS
authors.lastname: Dukhanin
authors.forename: E V
authors.initials: EV
authors.lastname: Solov'eva
mesh_terms: D045930:Anabolic Agents / Q000494:pharmacology*; D000818:Animals; D002455:Cell Division / Q000187:drug effects*; D004247:DNA / Q000378:metabolism; D003907:Dexamethasone / Q000494:pharmacology; D004441:Ecdysterone / Q000494:pharmacology; D008696:Methandrostenolone / Q000494:pharmacology; D051379:Mice; D008810:Mice, Inbred C57BL; D009929:Organ Size; D013739:Testosterone / Q000494:pharmacology; D013936:Thymidine / Q000378:metabolism; D013950:Thymus Gland / Q000166:cytology / Q000187:drug effects*
chemical_list: D045930:Anabolic Agents; D013739:Testosterone; D004441:Ecdysterone; D003907:Dexamethasone; D004247:DNA; D008696:Methandrostenolone; D013936:Thymidine
vernacular_title: Vliianie anabolicheskikh steroidov na proliferativnuiu aktivnost' timotsitov]