title: Malpighian corpuscles of spleen in infancy and childhood.
abstract: In early infancy splenic white pulp is seen arranged around the central arterioles. They do not show any reactive changes even in the presence of systemic infections. Lymphoid follicles are seen at 6 weeks of life. Germinal centres appear from the 8th week of life onwards. Periarteriolar lymphocytic sheaths persist in the older children along with the reactive changes.
authors.affiliation: Department of Pathology, Postgraduate Institute of Medical Education and Research, Chandigarh.
authors.forename: K
authors.initials: K
authors.lastname: Vaiphei
authors.forename: B N
authors.initials: BN
authors.lastname: Dutta
authors.forename: C K
authors.initials: CK
authors.lastname: Banerjee
mesh_terms: D000367:Age Factors; D001160:Arterioles / Q000033:anatomy & histology / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007239:Infections / Q000473:pathology*; D013154:Spleen / Q000033:anatomy & histology* / Q000098:blood supply / Q000473:pathology