title: [Evaluation of the hemodynamic effects of the long-acting peripheral vasodilator flosequinan in patients with chronic heart failure].
abstract: The hemodynamic effects of the peripheral vasodilator flosequinan, 100 mg/day, were evaluated in 20 patients with Stage IIA-IIB (the Lang-Strazhesko-Vasilenko classification) heart failure. The doses of digoxin and diuretics were found to be stable. The right cardiac cavities and pulmonary artery were catheterized by Swan-Ganz balloon catheters. The agent was demonstrated to produced profound effects showing decreased pre- and afterload when given both in a single dose or in course therapy.
authors.forename: U S
authors.initials: US
authors.lastname: Abdurakhmanov
authors.forename: V G
authors.initials: VG
authors.lastname: Naumov
authors.forename: S A
authors.initials: SA
authors.lastname: Shevliagin
authors.forename: S V
authors.initials: SV
authors.lastname: Novikov
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Mareev
authors.forename: Iu N
authors.initials: IuN
authors.lastname: Belenkov
mesh_terms: D000328:Adult; D002908:Chronic Disease; D006333:Heart Failure / Q000188:drug therapy / Q000503:physiopathology*; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011804:Quinolines / Q000494:pharmacology*; D014665:Vasodilator Agents / Q000494:pharmacology*
chemical_list: D011804:Quinolines; D014665:Vasodilator Agents; C047316:flosequinan
vernacular_title: Otsenka gemodinamicheskogo deĭstviia prolongirovannogo perifericheskogo vazodilatatora flozekvinana u bol'nykh s khronicheskoĭ serdechnoĭ nedostatochnost'iu.