title: [Distribution of harmful metals in sheep after experimental administration of industrial emissions].
abstract: Cu, Fe, Zn, Mo, Se, As, Cd and Pb distribution was followed in the organisms of seven lambing ewes after these animals had been on a diet with industrial contaminants generated by the copper and zinc works. The amount of ingested contaminants per lambing ewe was 31.99 g a day pursuant to the starting liveweight. Per-head daily intake of Cu, Fe, Zn, Mo, Se, As, Cd and Pb in mg: 402.02; 95.97; 6158.07; 1.436; 2.975; 15.38; 0.597; 22.14. The first ewe with symptoms of zinc intoxication died on day 42 and the last on day 58. The highest Zn concentrations were recorded in the dry matter of dead ewe liver (1167.3 +/- 314.1 mg per kg). An amount of 1048 +/- 283.7 mg Zn per kg was cumulated in the kidneys in the process of contaminant administration. High Zn contents were also observed in the uterus and spleen. The highest amounts of Cu were cumulated in liver (445.6 238.1 mg per kg). Spleen was an organ with the highest concentrations of Fe, the ovaries cumulated the highest amounts of Mo and bony tissue and ovaries the highest amounts of Se. An exposure of the organisms to As, Cd and Pb in ewes intoxicated with zinc from a source of industrial pollutants, was reflected in their high contents in the ovaries, kidneys, liver and bony tissue. These results demonstrate that in sheep the liver, kidneys, uterus, spleen and ovaries are the most suitable organs if it is to prove zinc intoxication caused by pollutants from the copper and zinc works. Liver, kidneys, ovaries, uterus, spleen, skeletal muscles and bony tissue seem to be suitable for an evaluation of Cu, Fe, Mo, Se, As, Cd and Pb distribution in the organisms of ewes which died from zinc intoxication caused by pollutants from the above-mentioned source.
authors.affiliation: Vysoká skola veterinárska, Kosice.
authors.forename: J
authors.initials: J
authors.lastname: Bíres
authors.forename: L
authors.initials: L
authors.lastname: Vrzgula
authors.forename: Z
authors.initials: Z
authors.lastname: Juhásová
mesh_terms: D000818:Animals; D004785:Environmental Pollutants / Q000493:pharmacokinetics*; D005260:Female; D008670:Metals / Q000493:pharmacokinetics*; D012756:Sheep / Q000378:metabolism*; D014018:Tissue Distribution
chemical_list: D004785:Environmental Pollutants; D008670:Metals
vernacular_title: Distribúcia rizikových kovov v organizme oviec po príjme priemyselnej emisie v experimente.