title: Methylpendolmycin, an indolactam from a Nocardiopsis sp.
abstract: Methylpendolmycin, a new indole alkaloid with an N-methylisoleucine moiety incorporated in the nine-membered indolactam ring, has been isolated from an actinomycete culture of Nocardiopsis. Methylpendolmycin exhibited inhibition of phorbol ester binding to protein kinase C. Its structure was assigned on the basis of spectroscopic data.
authors.affiliation: Department of Natural Products Chemistry, Sterling Research Group, Malvern, Pennsylvania 19355.
authors.forename: H H
authors.initials: HH
authors.lastname: Sun
authors.forename: C B
authors.initials: CB
authors.lastname: White
authors.forename: J
authors.initials: J
authors.lastname: Dedinas
authors.forename: R
authors.initials: R
authors.lastname: Cooper
authors.forename: D M
authors.initials: DM
authors.lastname: Sedlock
mesh_terms: D000192:Actinomycetales / Q000737:chemistry*; D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D007211:Indoles / Q000737:chemistry / Q000302:isolation & purification*; D007769:Lactams / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure
chemical_list: D000470:Alkaloids; D007211:Indoles; D007769:Lactams; C073640:methylpendolmycin