[Retrospective analysis of prognostic factors in patients with primary lymphoma of the intestine].
Forty-six patients with stage IE and IIE malignant lymphoma of the intestine were analyzed to assess the efficacy of prognostic factors to predict the course and therapeutic approach in these patients. Because the lesion was considered unresectable in all cases, chemotherapy was given after surgery. Using Cox's univariate regression analysis, survival was found to correlate with stage (IE vs IIE) and high levels of lactic dehidrogenase, nevertheless in the multivariate analysis only beta 2 microglobulin levels were associated with a shorter survival. We believe that treatment of extranodal lymphomas, like nodal presentations, as those of the intestine, could be based in the determinations of prognostic factors and that beta 2 microglobulin would be considered the most powerful prognostic factor. Most studies on patients with malignant lymphoma of the intestine are necessary to define the role of beta 2 microglobulin as therapeutic prognostic index.
Avilés
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Departamento de Hematología, Hospital de Oncología, Centro Médico Nacional, IMSS, México, D.F.
Guzmán
R
R
Huerta
J
J
Díaz-Maqueo
J C
JC
D000328:Adult; D005260:Female; D006801:Humans; D007414:Intestinal Neoplasms / Q000401:mortality* / Q000628:therapy; D008223:Lymphoma / Q000401:mortality* / Q000628:therapy; D008297:Male; D015999:Multivariate Analysis; D011379:Prognosis; D012189:Retrospective Studies; D016019:Survival Analysis
Análisis retrolectivo de factores pronósticos en pacientes con linfoma primario de intestino.