[Selective resection of the lateral semicircular canal with hearing preservation--an animal experiment study].
The goal of our investigation was to develop a method for removing parts of the vestibular labyrinth by surgery without inducing a loss of auditory function. Three different surgical lesions were created in the lateral semicircular canal of the rabbit: (1) fenestration; (2) fibrin glue perfusion of the canal following fenestration; and (3) destruction of the semicircular canal by drilling after fenestration and fibrin glue perfusion. Brain-stem auditory potentials were recorded repeatedly up to 3 months after operation. They demonstrated preservation of hearing in all rabbits in the first group, in 78% of the second and 67% of the third group. In the last group a 20 dB deterioration of hearing was regularly noticed. Histological study revealed the utmost importance of the fibrin glue perfusion of the perilymph space of the semicircular canal inducing an interruption of the peri- and endolymph flow. A precise microsurgical technique was crucial for hearing preservation.
Gjuric
M
M
Hals-Nasen-Ohrenklinik der Universität Erlangen-Nürnberg.
Wigand
M E
ME
Hosemann
W
W
Berg
M
M
D000818:Animals; D001309:Auditory Threshold / Q000502:physiology; D001933:Brain Stem / Q000503:physiopathology; D004710:Endolymph / Q000502:physiology; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology; D005276:Fenestration, Labyrinth / Q000379:methods*; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage; D006309:Hearing / Q000502:physiology*; D008297:Male; D010498:Perilymph / Q000502:physiology; D011817:Rabbits; D012665:Semicircular Canals / Q000503:physiopathology* / Q000601:surgery*
D015718:Fibrin Tissue Adhesive
Selektive Resektion des lateralen Bogengangs mit Gehörerhaltungeine tierexperimentelle Studie.