[Amyloidosis in children with rheumatoid arthritis and the results of its long-term treatment with colchicine].
The authors provide materials of a clinical follow-up of 23 children suffering from rheumatoid arthritis (RA) with an outcome of amyloidosis of the internal organs, supported by morphological examination in 13 patients. 10 patients were treated with colchicine in a dose of 1-2 mg/day lasting from 6 months to 2 years and 7 months. The beneficial effect was attained in 7 children. In 3 patients with RA standing over 8 years, the results were negative. Colchicine merits attention as an effective drug for the treatment of secondary amyloidosis in RA patients.
Iandashevskaia
S I
SI
Iakovleva
A A
AA
Dvoriakovskaia
G M
GM
Sibiriakova
L G
LG
D000293:Adolescent; D000686:Amyloidosis / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D001171:Arthritis, Juvenile / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D002648:Child; D003078:Colchicine / Q000627:therapeutic use*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D008297:Male; D009404:Nephrotic Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D013997:Time Factors
D003078:Colchicine
Amiloidoz u deteĭ, bol'nykh revmatoidnym artritom, i rezul'taty dlitel'nogo ego lecheniia kolkhitsinom.