title: [The use of obzidan and metoprolol in patients with supraventricular systolic tachyarrhythmias].
abstract: Having analyzed the electrophysiological mechanisms and state of humoral regulatory substances in 87 patients with paroxysmal disorders of the cardiac rhythm the authors determined the antiarrhythmic action of two beta-blockaders: obsidan and metoprolol. They found a reduction of the sinus node function under the effect of obsidan and to a lesser degree under the effect of metoprolol. Metoprolol produced a high antiarrhythmic effect, particularly in supraventricular tachycardias with participation of abnormal conduction pathways.
authors.forename: A I
authors.initials: AI
authors.lastname: Frolov
authors.forename: V A
authors.initials: VA
authors.lastname: Bobrov
authors.forename: E I
authors.initials: EI
authors.lastname: Mitchenko
authors.forename: E M
authors.initials: EM
authors.lastname: Chervonopiskaia
authors.forename: I V
authors.initials: IV
authors.lastname: Galichanskiĭ
authors.forename: N V
authors.initials: NV
authors.lastname: Delikatnaia
mesh_terms: D000293:Adolescent; D000328:Adult; D004341:Drug Evaluation; D005260:Female; D006329:Heart Conduction System / Q000187:drug effects / Q000503:physiopathology; D006339:Heart Rate / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008297:Male; D008790:Metoprolol / Q000494:pharmacology / Q000627:therapeutic use*; D008875:Middle Aged; D010053:Ovary / Q000187:drug effects / Q000503:physiopathology; D011433:Propranolol / Q000494:pharmacology / Q000627:therapeutic use*; D013617:Tachycardia, Supraventricular / Q000188:drug therapy* / Q000503:physiopathology; D013737:Testis / Q000187:drug effects / Q000503:physiopathology; D013961:Thyroid Gland / Q000187:drug effects / Q000503:physiopathology
chemical_list: D011433:Propranolol; D008790:Metoprolol
vernacular_title: Primenenie obzidana i metoprolola u bol'nykh s supraventrikuliarnymi takhisistolicheskimi aritmiiami.