Studies on the control of hookworm and other soil-transmitted helminthiases in farmers in Zhejiang Province, China.
Different periodic selective chemotherapeutic schemes were used to control hookworm and other soil-transmitted helminthiases in eight villages in five counties in Zhejiang Province, China, 1985-1988. The results showed that the prevalence rates of hookworm, ascariasis, and trichuriasis decreased from 35.0-74.4%, 47.0-.76% and 22.9-47.5% to 3.2-15.8%, 9.9-47.8%, and 3.5-31.2%, respectively, using pyrantel pamoate (10 mg/kg for 1-2 days) or albendazole (400 mg for 1-2 days, once or twice a year for 2-3 years). The eggs per gram of feces of hookworm and Trichuris trichiura also dropped markedly after control. Moreover, the mean hemoglobin levels of sampled populations increased after several treatments. The authors recommend periodic selective chemotherapy as the main method to control soil-transmitted helminthiases, especially hookworm infections.
Xia
Z H
ZH
Institute of Parasitic Diseases, Zhejiang Academy of Medical Sciences, Hangzhou, People's Republic of China.
Yao
S Y
SY
Su
Y L
YL
Yao
L Y
LY
Wen
L Y
LY
Song
C C
CC
D000383:Agriculture; D015766:Albendazole / Q000008:administration & dosage / Q000627:therapeutic use*; D000818:Animals; D001196:Ascariasis / Q000188:drug therapy* / Q000453:epidemiology / Q000635:transmission; D001200:Ascaris; D002648:Child; D002681:China / Q000453:epidemiology; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006725:Hookworm Infections / Q000188:drug therapy* / Q000453:epidemiology / Q000635:transmission; D006801:Humans; D007814:Larva; D008297:Male; D011716:Pyrantel Pamoate / Q000008:administration & dosage / Q000627:therapeutic use*; D014257:Trichuriasis / Q000188:drug therapy* / Q000453:epidemiology / Q000635:transmission
D006454:Hemoglobins; D011716:Pyrantel Pamoate; D015766:Albendazole