[Nasal chemoreception in utero: preliminary experiences in fetal sheep].
Intranasal injections of a fragrant solution of 2-methyl-2-thiazoline elicited significant heart rate decelerations in late pregnancy fetal sheep, while the injection of a control fluid (isotonic saline) had no effect. This result indicates that the ovine fetuses are able to detect nasally administered odorants, as previously demonstrated in the fetuses of murine rodents.
Schaal
B
B
Laboratoire de Psychobiologie de l'Enfant, E.P.H.E.-C.N.R.S. (U.R.A. n. 315), Paris.
Orgeur
P
P
Lecanuet
J P
JP
Locatelli
A
A
Granier-Deferre
C
C
Poindron
P
P
D000281:Administration, Intranasal; D000818:Animals; D005260:Female; D005318:Fetal Heart / Q000502:physiology*; D006339:Heart Rate / Q000187:drug effects*; D008297:Male; D009812:Odorants / Q000032:analysis; D011247:Pregnancy; D012756:Sheep / Q000196:embryology*; D013844:Thiazoles / Q000008:administration & dosage / Q000494:pharmacology*
D013844:Thiazoles; C025765:2-methylthiazoline
Chimioréception nasale in utero: expériences préliminaires chez le foetus ovin.