title: Evidence for energy-dependent copper efflux as a mechanism of Cu2+ resistance in the cyanobacterium Nostoc calcicola.
abstract: Wild-type Nostoc calcicola carried out oxygenic photosynthesis extremely sensitive to copper. A Cu(2+)-resistant mutant (Cu-R1) of the cyanobacterium grew normally at high concentrations of Cu2+. Its ability to grow under such conditions was found to be due to mutational acquisition of an energy-dependent efficient system of Cu(2+)-efflux, which rendered Cu(2+)-inhibited oxygenic photosynthesis fully reversible.
authors.affiliation: School of Life Sciences, University of Hyderabad, India.
authors.forename: S K
authors.initials: SK
authors.lastname: Verma
authors.forename: H N
authors.initials: HN
authors.lastname: Singh
mesh_terms: D001693:Biological Transport, Active; D003300:Copper / Q000378:metabolism* / Q000494:pharmacology / Q000633:toxicity; D000458:Cyanobacteria / Q000187:drug effects / Q000378:metabolism*; D004024:Dicyclohexylcarbodiimide / Q000494:pharmacology; D004237:Diuron / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D009154:Mutation; D010100:Oxygen / Q000378:metabolism; D010788:Photosynthesis / Q000187:drug effects
chemical_list: D004024:Dicyclohexylcarbodiimide; D003300:Copper; D004237:Diuron; D010100:Oxygen