title: [Neuroendocrine aspects of the pathogenesis of fatty pancreonecrosis].
abstract: In fatty pancreonecrosis, ejection of the considerable amount of endogenous insulin into the blood occurs. Insulin is a potent inhibitor of gluconeogenesis, a most important hormone of lipogenesis, and at the same time considerably inhibits lipolysis. This defines its pathogenetic role in the development of fatty pancreonecrosis.
authors.forename: Iu P
authors.initials: IuP
authors.lastname: Sheverdin
mesh_terms: D004789:Enzyme Activation / Q000502:physiology; D006801:Humans; D006946:Hyperinsulinism / Q000150:complications* / Q000378:metabolism; D007328:Insulin / Q000502:physiology*; D008049:Lipase / Q000502:physiology; D008066:Lipolysis / Q000502:physiology*; D009336:Necrosis; D010179:Pancreas / Q000378:metabolism* / Q000473:pathology; D010182:Pancreatic Diseases / Q000209:etiology*; D010740:Phospholipases / Q000502:physiology
chemical_list: D007328:Insulin; D010740:Phospholipases; D008049:Lipase
vernacular_title: Neĭroéndokrinnye aspekty patogeneza zhirovogo pankreonekroza.