[Measurement of plasma malondialdehyde contents and erythrocyte superoxide dismutase activities in patients with chronic cor pulmonale].
We measured the contents of plasma MDA and erythrocyte SOD activities in patients with chronic cor pulmonale. The contents of malondialdehyde (MDA) increased; the superoxide dismutase (SOD) activities suppressed significantly and reoxygenation caused increases in the SOD activities in patients with acute attacks. But the changes of the contents of MDA and SOD activities did not appear in patients with stationary phase. These results indicate that oxygen free radicals may contribute to the physiopathological process of chronic cor pulmonale.
Cheng
P
P
Department of Internal Medicine, Second Affiliated Hospital of Hunan Medical University, Changsha.
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D006801:Humans; D008297:Male; D008315:Malondialdehyde / Q000097:blood*; D008875:Middle Aged; D011660:Pulmonary Heart Disease / Q000097:blood* / Q000201:enzymology; D013482:Superoxide Dismutase / Q000097:blood*
D008315:Malondialdehyde; D013482:Superoxide Dismutase