title: In vivo and in vitro studies on soft denture materials: microbial adhesion and tests for antibacterial activity.
abstract: The microbiological properties of four tissue conditioners, one soft liner, and one acrylic resin were studied. The tissue conditioners showed no or negligible antimicrobial effects toward salivary microorganisms by two different in vitro tests. In in vitro adhesion experiments, more Streptococcus mutans and Candida albicans adhered to the tissue conditioners and the soft liner in comparison with conventional acrylic resin used for denture-base fabrication. No difference in bacterial adhesion was found among the tissue conditioners. The microbial colonization of two tissue conditioners lined on maxillary dentures in three volunteers was followed for 14 days. No difference among the materials was found, but a tendency for subject-dependence in plaque formation on the materials was noted.
authors.affiliation: Department of Prosthodontics, Dental Faculty, University of Oslo.
authors.forename: N
authors.initials: N
authors.lastname: Okita
authors.forename: D
authors.initials: D
authors.lastname: Orstavik
authors.forename: J
authors.initials: J
authors.lastname: Orstavik
authors.forename: K
authors.initials: K
authors.lastname: Ostby
mesh_terms: D000180:Acrylic Resins; D000368:Aged; D001422:Bacterial Adhesion / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects*; D003819:Denture Bases; D003822:Denture Liners; D004129:Dimethylpolysiloxanes; D005260:Female; D006801:Humans; D008297:Male; D008422:Materials Testing; D008689:Methacrylates; D008768:Methylmethacrylates; D008875:Middle Aged; D010795:Phthalic Acids; D012826:Silicone Elastomers; D013295:Streptococcus mutans / Q000187:drug effects*; D014016:Tissue Conditioning, Dental
chemical_list: D000180:Acrylic Resins; D004129:Dimethylpolysiloxanes; C074498:Futur Acryl 2000; C020964:MDX 4-4210; D008689:Methacrylates; D008768:Methylmethacrylates; D010795:Phthalic Acids; D012826:Silicone Elastomers; C073909:GC Soft-Liner; C043685:Coe Comfort; C009931:poly(ethylmethacrylate)