title: [Nasal chemoreception in utero: preliminary experiences in fetal sheep].
abstract: Intranasal injections of a fragrant solution of 2-methyl-2-thiazoline elicited significant heart rate decelerations in late pregnancy fetal sheep, while the injection of a control fluid (isotonic saline) had no effect. This result indicates that the ovine fetuses are able to detect nasally administered odorants, as previously demonstrated in the fetuses of murine rodents.
authors.affiliation: Laboratoire de Psychobiologie de l'Enfant, E.P.H.E.-C.N.R.S. (U.R.A. n. 315), Paris.
authors.forename: B
authors.initials: B
authors.lastname: Schaal
authors.forename: P
authors.initials: P
authors.lastname: Orgeur
authors.forename: J P
authors.initials: JP
authors.lastname: Lecanuet
authors.forename: A
authors.initials: A
authors.lastname: Locatelli
authors.forename: C
authors.initials: C
authors.lastname: Granier-Deferre
authors.forename: P
authors.initials: P
authors.lastname: Poindron
mesh_terms: D000281:Administration, Intranasal; D000818:Animals; D005260:Female; D005318:Fetal Heart / Q000502:physiology*; D006339:Heart Rate / Q000187:drug effects*; D008297:Male; D009812:Odorants / Q000032:analysis; D011247:Pregnancy; D012756:Sheep / Q000196:embryology*; D013844:Thiazoles / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D013844:Thiazoles; C025765:2-methylthiazoline
vernacular_title: Chimioréception nasale in utero: expériences préliminaires chez le foetus ovin.