Arecoline-associated changes in open-field behavior following swim stress in the rat. A possible relationship to water temperature.
The rat exhibits a reduction in movement in an open field following a 14-day course of forced swim stress at 12 degrees C. The decrease in movement is greater in rats receiving arecoline relative to those receiving saline prior to placement in the open field. The authors report that when water temperature is increased to 20 degrees, there is a categorical difference in the results. The saline control group exhibits a rise and the arecoline group no change in crossings.
Jaeckle
R S
RS
Department of Psychiatry, Ohio State University, Columbus 43210-1228.
Dilsaver
S C
SC
Hoh
J
J
Peck
J A
JA
D000818:Animals; D001115:Arecoline / Q000494:pharmacology*; D001522:Behavior, Animal / Q000187:drug effects*; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D013312:Stress, Physiological / Q000523:psychology; D013550:Swimming; D013696:Temperature; D014867:Water
D014867:Water; D001115:Arecoline