Distribution of argyrophilic proteins in the nuclei of hepatocytes.
The ultrastructural study on the distribution of argyrophilic proteins of hepatocytes was carried out. Because it has been suggested that the numbers of silver grains were connected with transcriptional activity of nucleoli, we used in our studies as a model the regenerating liver. Among extranucleolar structures affinity to silver interchromatin granules and weakly perichromatin granules was demonstrated. Deposits of silver grains were always located within dense fibrillar components and fibrillar centers. Our study does not enable to indicate a direct relationship between numbers of silver grains deposits and transcriptional activity of nucleoli.
Orkisz
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S
Department of Histology and Embryology, Military Academy of Medicine, Lódź, Poland.
Bartel
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H
D000818:Animals; D002466:Cell Nucleolus / Q000737:chemistry / Q000502:physiology / Q000648:ultrastructure; D002467:Cell Nucleus / Q000737:chemistry* / Q000502:physiology / Q000648:ultrastructure; D002843:Chromatin / Q000737:chemistry / Q000648:ultrastructure; D006498:Hepatectomy; D008099:Liver / Q000737:chemistry / Q000166:cytology* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D009687:Nuclear Proteins / Q000032:analysis* / Q000378:metabolism / Q000502:physiology; D009697:Nucleolus Organizer Region / Q000737:chemistry / Q000502:physiology / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains; D012836:Silver Proteins / Q000032:analysis*; D014158:Transcription, Genetic / Q000502:physiology
D002843:Chromatin; D009687:Nuclear Proteins; D012836:Silver Proteins