title: The response of evidential breath alcohol testing instruments with subjects exposed to organic solvents and gases. I. Toluene, 1,1,1-trichloroethane and butane.
abstract: Experimental work has been undertaken to investigate the potential interference of toluene, 1,1,1-trichloroethane and butane with the evidential breath alcohol testing instruments used in Great Britain (Lion Intoximeter 3000 and Camic Breath Analyser). Volunteers inhaled the volatile substances in an exposure chamber for up to 4 hours, at concentrations of 100, 350 and 600ppm respectively. Subsequently breath was tested on leaving the chamber. No interference was observed with the breath alcohol instruments when the subjects were exposed to toluene and 1,1,1-trichloroethane. A short-term response immediately after exposure was observed for subjects exposed to butane. Further analytical work involving blood and breath samples demonstrated that all three volatile substances were absorbed during exposure and were detectable in blood for at least 3 hours post-exposure. Their elimination post-exposure followed an exponential decay.
authors.affiliation: Central Research and Support Establishment, Home Office Forensic Science Service, Aldermaston, Reading, Berkshire.
authors.forename: R
authors.initials: R
authors.lastname: Gill
authors.forename: S E
authors.initials: SE
authors.lastname: Hatchett
authors.forename: C G
authors.initials: CG
authors.lastname: Broster
authors.forename: M D
authors.initials: MD
authors.lastname: Osselton
authors.forename: J D
authors.initials: JD
authors.lastname: Ramsey
authors.forename: H K
authors.initials: HK
authors.lastname: Wilson
authors.forename: A H
authors.initials: AH
authors.lastname: Wilcox
mesh_terms: D000328:Adult; D001273:Atmosphere Exposure Chambers; D001944:Breath Tests; D002073:Butanes / Q000032:analysis; D005260:Female; D005740:Gases / Q000032:analysis*; D006801:Humans; D008297:Male; D016273:Occupational Exposure; D012997:Solvents / Q000032:analysis*; D014050:Toluene / Q000032:analysis; D014240:Trichloroethanes / Q000032:analysis
chemical_list: D002073:Butanes; D005740:Gases; D012997:Solvents; D014240:Trichloroethanes; C024566:1,1,1-trichloroethane; D014050:Toluene; C046888:butane