Clinical and bacterial features of infections caused by Streptococcus milleri.
The clinical and bacteriological features of 51 infections due to Streptococcus milleri observed in 43 patients over a 2-year period were reviewed. Clinical syndromes included bacteremia in 6 cases, endocarditis in 4 cases, cellulitis and subcutaneous abscesses in 8 cases, pleural empyema in 8 cases, brain abscesses in 5 cases, abdominal infections in 5 cases, and other miscellaneous infections in 15 cases. An underlying condition was associated with infection in 33/43 patients (77%). S. milleri was the only pathogen isolated in 19 patients (44%). All strains of S. milleri were susceptible to penicillin. Surgery was combined with antimicrobial therapy in 27 (63%) patients. Nine patients died during hospitalization, and death was directly related to S. milleri infection in 4 patients (9%). These results confirm that S. milleri frequently causes serious suppurative infections and that species identification is a clinically useful procedure.
Molina
J M
JM
Division of Infectious Diseases, Claude Bernard Hospital, Paris, France.
Leport
C
C
Bure
A
A
Wolff
M
M
Michon
C
C
Vilde
J L
JL
D000038:Abscess / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016470:Bacteremia / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D001922:Brain Abscess / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D002481:Cellulitis / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D002648:Child; D016724:Empyema, Pleural / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D005260:Female; D006801:Humans; D008100:Liver Abscess / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D008297:Male; D016920:Meningitis, Bacterial / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D008875:Middle Aged; D010538:Peritonitis / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D012189:Retrospective Studies; D013290:Streptococcal Infections / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D013291:Streptococcus / Q000187:drug effects / Q000302:isolation & purification*; D016896:Treatment Outcome