title: Cage ammonia levels during murine reproduction.
abstract: Monogamous pairs of inbred BALB/c and outbred CD-1 mice housed in M2 cages with a floor area of 330 cm2, produced a mean cage ammonia level of 26 ppm and 154 ppm respectively over a four day period prior to weaning their litters. A gradient of ammonia exists from the nest to the food hopper. By housing CD-1 monogamous pairs in RM2 cages which have double the floor area of M2 cages (676 cm2), a lower mean level of ammonia was recorded at the same stage of reproduction and air sampling. The CD-1 mice in particular, were subjected to high levels of ammonia when compared with long term human health and safety occupational exposure limits of 25 ppm.
authors.affiliation: AFRC Institute for Animal Health, Pirbright Laboratory, U.K.
authors.forename: J R
authors.initials: JR
authors.lastname: Eveleigh
mesh_terms: D000641:Ammonia / Q000009:adverse effects* / Q000032:analysis; D000818:Animals; D004781:Environmental Exposure; D005260:Female; D006799:Housing, Animal / Q000592:standards*; D008297:Male; D051379:Mice / Q000502:physiology*; D008807:Mice, Inbred BALB C / Q000502:physiology*; D012098:Reproduction / Q000187:drug effects*
chemical_list: D000641:Ammonia