Effect on ochratoxin A on Lohmann-type chicks.
Ochratoxin A was fed at 0.5 ppm to Lohmann-type chicks from 7 d of age for 4 w. Body weights and efficiency of feed utilization were depressed and the activity of serum SDH and GDH and the concentration of uric acid were significantly increased. The concentration of serum total protein and potassium and Hb, PCV, RBC and WBC were significantly decreased in the test group. Lesions were seen in vital organs, with hemorrhage in the thigh. A slow recovery in the kidney was observed 3 w after removal from the experimental diet.
Ayed
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IA
Department of Veterinary Medicine, Pharmacology and Toxicology, University of Khartoum, Sudan.
Dafalla
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R
Yagi
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Adam
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D000821:Animal Feed; D000818:Animals; D001772:Blood Cell Count; D001835:Body Weight / Q000187:drug effects; D002645:Chickens; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary; D005969:Glutamate Dehydrogenase / Q000097:blood; D007668:Kidney / Q000473:pathology; D008099:Liver / Q000473:pathology; D008297:Male; D009206:Myocardium / Q000473:pathology; D009793:Ochratoxins / Q000633:toxicity*; D011188:Potassium / Q000097:blood; D011201:Poultry Diseases / Q000139:chemically induced* / Q000473:pathology; D013154:Spleen / Q000473:pathology; D013385:Succinate Dehydrogenase / Q000097:blood; D013848:Thigh / Q000473:pathology; D014527:Uric Acid / Q000097:blood
D009793:Ochratoxins; C025589:ochratoxin A; D014527:Uric Acid; D013385:Succinate Dehydrogenase; D005969:Glutamate Dehydrogenase; D011188:Potassium