title: Surgical treatment of myasthenia gravis and evaluation of its efficacy.
abstract: This paper reports 30 cases of myasthenia gravis (MG) treated by thymectomy from 1965 to 1990 in our hospital. Of all the 30 cases of MG, peripheral blood lymphocyte subpopulation was determined in 10, and anti-acetylcholine receptor antibody titer in 6, before and after operation. The results demonstrated the efficacy of thymectomy against MG. We considered that with application of hormone before and after operation to regulate immune function of the body, and/or with plasma exchange to remiss symptoms, all the patients with generalized MG may be indicated for treatment by thymectomy. Indication of treatment does not depend on age, sex and the course of the disease. But radical operation, proper anesthesia and appropriate use of antibiotics may ensure safety of the operation and its curative effect.
authors.affiliation: Department of Surgery, Tongji Hospital, Tongji Medical University, Wuhan.
authors.forename: T C
authors.initials: TC
authors.lastname: Pan
authors.forename: Q F
authors.initials: QF
authors.lastname: Chen
authors.forename: L H
authors.initials: LH
authors.lastname: Zhang
authors.forename: Y Z
authors.initials: YZ
authors.lastname: Shen
authors.forename: Z P
authors.initials: ZP
authors.lastname: Xie
authors.forename: M S
authors.initials: MS
authors.lastname: Yang
authors.forename: B T
authors.initials: BT
authors.lastname: Bu
authors.forename: X B
authors.initials: XB
authors.lastname: Cao
mesh_terms: D000293:Adolescent; D000328:Adult; D016516:CD4-CD8 Ratio; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000209:etiology / Q000276:immunology / Q000601:surgery*; D016176:T-Lymphocyte Subsets / Q000276:immunology; D013934:Thymectomy / Q000379:methods; D013945:Thymoma / Q000150:complications; D013952:Thymus Hyperplasia / Q000150:complications; D013953:Thymus Neoplasms / Q000150:complications