[The clinico-morphological characteristics of synovial membrane involvement in beta-thalassemia].
Using data on optic and electron microscopy the authors give characteristics of lesions in the synovial membrane of the knee joints in 6 patients with an intermediary form of beta-thalassemia. Multiple reduplication of the basal membrane was noted in all the vessels, the width of the noncellular component of the vessels increased several times and its stratification was clearly seen. Deposits of iron oxide were revealed in biopsy samples of the synovial membrane of all the patients. Those deposits were in the form of microgranular intracellular inclusions in phagocytosing cells of the superficial stroma of villi but more often they were found in the cytoplasm of the vessel cells and pericytes.
Nasonova
V A
VA
Musaev
S K
SK
Iakovleva
G I
GI
Abasov
E Sh
ESh
Rustamov
R Sh
RSh
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D005290:Ferric Compounds / Q000378:metabolism; D006651:Histocytochemistry; D006801:Humans; D007719:Knee Joint; D008854:Microscopy, Electron; D013583:Synovial Membrane / Q000378:metabolism / Q000648:ultrastructure*; D013789:Thalassemia / Q000378:metabolism / Q000473:pathology*
D005290:Ferric Compounds; C000499:ferric oxide
Kliniko-morfologicheskaia kharakteristika porazheniia sinovial'noĭ obolochki pri beta-talassemii.