[The first trial of treating opisthorchiasis with the Soviet preparation azinoks].
7 patients in the acute and 51 patients in the chronic stages of opisthorchiasis were treated with azynoks in daily dose 60 mg per kilo. The radical cure was achieved in 95.8 +/- 0.4% of cases. The wild side effects (headache, vertigo, nausea, fatigue) were registered in 51.7 +/- 9.1% of the cases, predominantly during the first hours of the treatment. The biochemical and immunological changes during the first 2 weeks after azynoks administration were analogues to those seen after biltricide and chloxyl (hexaparaxylol) treatment.
Stepanova
T F
TF
Pomigalov
A Iu
AIu
Shonin
A L
AL
Postnikova
T F
TF
Emel'ianova
E D
ED
Maĭer
V A
VA
Skarednov
N I
NI
D000293:Adolescent; D000328:Adult; D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood; D005243:Feces / Q000469:parasitology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009889:Opisthorchiasis / Q000097:blood / Q000188:drug therapy* / Q000469:parasitology; D009891:Opisthorchis / Q000276:immunology / Q000302:isolation & purification; D010270:Parasite Egg Count; D011223:Praziquantel / Q000009:adverse effects / Q000627:therapeutic use*
D000909:Antibodies, Helminth; D011223:Praziquantel
Pervyĭ opyt lecheniia opistorkhoza otechestvennym preparatom azinoksom.