title: [Diagnosis and surgical treatment of myasthenia gravis in childhood].
abstract: Thirty-year experience in surgical treatment of myasthenia in children and adolescents (175 patients) is generalized. It provides evidence of delayed recognition of this disease in many patients and of prolonged, often ineffective nonoperative treatment. Operation for thymectomy should be one of the main methods for the management of myasthenia in children. Operative treatment is indicated in a disease of moderate severity or in a severe course of myasthenia, particularly in patients with the first type of immunomorphological changes. It is important to amend the myasthenic disorders before the operation by means of maximally possible doses of anticholinesterases with addition of corticosteroids, whenever necessary. Whatever the method of treatment chosen, the patients must be kept under skilled dynamic control. Excellent and good late-term results were produced in 84.6% of cases.
authors.forename: P S
authors.initials: PS
authors.lastname: Vetshev
authors.forename: O S
authors.initials: OS
authors.lastname: Shkrob
authors.forename: O V
authors.initials: OV
authors.lastname: Zaĭrat'iants
authors.forename: I Kh
authors.initials: IKh
authors.lastname: Ippolitov
authors.forename: D I
authors.initials: DI
authors.lastname: Shagal
authors.forename: K E
authors.initials: KE
authors.lastname: Chilingaridi
authors.forename: A V
authors.initials: AV
authors.lastname: Kurochkin
mesh_terms: D000293:Adolescent; D002648:Child; D002800:Cholinesterase Inhibitors / Q000008:administration & dosage*; D003907:Dexamethasone / Q000008:administration & dosage*; D006801:Humans; D008197:Lymph Node Excision; D009157:Myasthenia Gravis / Q000175:diagnosis / Q000601:surgery*; D011239:Prednisolone / Q000008:administration & dosage*; D011300:Preoperative Care; D012720:Severity of Illness Index; D013934:Thymectomy / Q000379:methods*
chemical_list: D002800:Cholinesterase Inhibitors; D003907:Dexamethasone; D011239:Prednisolone
vernacular_title: Diagnostika i khirurgicheskoe lechenie miastenii v detskom vozraste.