title: Long-lasting decrease in the crayfish giant motoneuron soma excitability induced by Ca2+ influx.
abstract: After a single Ca-dependent action-potential or a 300 ms clamp pulse to 0 mV in the motor giant somata of the crayfish abdominal nerve cord, a decrease in input resistance, an afterhyperpolarisation and a shortening of the test action potentials were observed during 10-15 min. These effects were due to a novel type of long-lasting outward current, triggered by a single influx of Ca2+, resistant to TEA+ and blocked by Ba2+.
authors.affiliation: Laboratoire de Neurobiologie Cellulaire, Faculté des Sciences, Université de Picardie, Amiens, France.
authors.forename: M
authors.initials: M
authors.lastname: Roux-Bruxelle
authors.forename: J
authors.initials: J
authors.lastname: Czternasty
authors.forename: J
authors.initials: J
authors.lastname: Bruner
mesh_terms: D000200:Action Potentials / Q000187:drug effects; D000818:Animals; D003400:Astacoidea; D001464:Barium / Q000494:pharmacology*; D017609:Barium Compounds; D002118:Calcium / Q000378:metabolism*; D002712:Chlorides; D005724:Ganglia / Q000502:physiology; D066298:In Vitro Techniques; D009046:Motor Neurons / Q000187:drug effects / Q000502:physiology*; D019789:Tetraethylammonium; D013757:Tetraethylammonium Compounds / Q000494:pharmacology; D013997:Time Factors
chemical_list: D017609:Barium Compounds; D002712:Chlorides; D013757:Tetraethylammonium Compounds; C024986:barium chloride; D001464:Barium; D019789:Tetraethylammonium; D002118:Calcium