Biochemical thyroid profile in patients infected with the human immunodeficiency virus.
Over a 2-year period, thyroid function was studied in 102 patients infected with the human immunodeficiency virus (HIV) and in 102 age- and sex-matched controls with various infectious diseases. Biochemical abnormalities were observed in 1-20% of the patients, depending on thyroid indices, but thyroid disease (hypothyroidism) was diagnosed in only 1. Compared to controls, patients, especially those with the acquired immunodeficiency syndrome (AIDS), had a significant increase in serum thyroxine-binding globulin, a lower T3 and free thyroxine index, and a higher frequency of thyroglobulin antibodies.
Bourdoux
P P
PP
Laboratory of Experimental Medicine, Saint Pierre University Hospital, Brussels, Belgium.
De Wit
S A
SA
Servais
G M
GM
Clumeck
N
N
Bonnyns
M A
MA
D000328:Adult; D000368:Aged; D000906:Antibodies / Q000032:analysis / Q000276:immunology; D005260:Female; D015658:HIV Infections / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013954:Thyroglobulin / Q000276:immunology; D013961:Thyroid Gland / Q000276:immunology / Q000378:metabolism / Q000502:physiology*; D013974:Thyroxine / Q000097:blood; D013975:Thyroxine-Binding Proteins / Q000378:metabolism; D014284:Triiodothyronine / Q000097:blood
D000906:Antibodies; D013975:Thyroxine-Binding Proteins; D014284:Triiodothyronine; D013954:Thyroglobulin; D013974:Thyroxine