title: Intraoral biopsy technique for direct immunofluorescence studies.
abstract: A wedge biopsy technique is described for use when oral manifestations of vesiculoerosive disease are suspected. The resultant soft tissue specimens are submitted for both light microscopic and direct immunofluorescence studies. This technique offers the advantage of obtaining highly diagnostic, mirror-image soft tissue specimens from a single perilesional site while minimizing postsurgical morbidity to the patient.
authors.affiliation: Department of Oral Medicine and Diagnostic Sciences Dental School, University of Maryland, Baltimore 21201.
authors.forename: M A
authors.initials: MA
authors.lastname: Siegel
mesh_terms: D001706:Biopsy / Q000379:methods; D003937:Diagnosis, Differential; D005455:Fluorescent Antibody Technique; D006801:Humans; D008856:Microscopy, Fluorescence / Q000379:methods; D009059:Mouth Diseases / Q000175:diagnosis / Q000473:pathology*; D009061:Mouth Mucosa / Q000473:pathology*; D010390:Pemphigoid, Benign Mucous Membrane / Q000175:diagnosis; D010392:Pemphigus / Q000175:diagnosis; D012872:Skin Diseases, Vesiculobullous / Q000175:diagnosis / Q000473:pathology*