Exploiting the molecular template of angiotensinogen in the discovery and design of peptidyl, pseudopeptidyl and peptidimimetic inhibitors of human renin: a structure-activity perspective.
Sawyer
T K
TK
Upjohn Laboratories, Upjohn Company, Kalamazoo, Michigan 49001.
Hester
J B
JB
Schostarez
H J
HJ
Thaisrivongs
S
S
Bundy
G L
GL
Liu
L
L
Bradford
V S
VS
De Vaux
A E
AE
Staples
D J
DJ
Maggiora
L L
LL
D000595:Amino Acid Sequence; D000808:Angiotensinogen / Q000031:analogs & derivatives / Q000737:chemistry* / Q000494:pharmacology; D001665:Binding Sites; D006801:Humans; D066298:In Vitro Techniques; D008958:Models, Molecular; D008969:Molecular Sequence Data; D012083:Renin / Q000737:chemistry; D013329:Structure-Activity Relationship; D013379:Substrate Specificity; D000092502:Renin Inhibitors
D000808:Angiotensinogen; D012083:Renin; D000092502:Renin Inhibitors