[Structural analysis of the brain microvessel permeability to metals in bacterial meningoencephalitis].
Concentration of a large group of metals in the blood and liquor of 70 patients with bacterial encephalitis is studied by atomic-absorption spectrometry. Correlation analysis showed that in patients with brain edema microvessels behave in relation to metals as a linear dynamic system. Postmortem light microscopic and scanning electron microscopic study of 3 brains found a predominant damage to endothelial cells and argyrophilic component of the microvessel basal membrane in the brain and cerebellum cortex and basal nuclei. Various degree of the structural changes of the microcirculation and the state of the permeability results in a nonhomogeneous accumulation of metals in the brain tissue.
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D001424:Bacterial Infections / Q000378:metabolism*; D001921:Brain / Q000098:blood supply*; D001929:Brain Edema / Q000378:metabolism*; D002199:Capillary Permeability / Q000502:physiology*; D006801:Humans; D008297:Male; D008590:Meningoencephalitis / Q000378:metabolism*; D008670:Metals / Q000493:pharmacokinetics*; D008833:Microcirculation / Q000502:physiology; D008875:Middle Aged
D008670:Metals
Strukturnyĭ analiz pronitsaemosti mikrososudov golovnogo mozga dlia metallov pri bakterial'nom meningoéntsefalite.