Aspects of stability of regional cerebral blood flow in chronic schizophrenia: an 18-year followup study.
Regional cerebral blood flow (rCBF) measurements and psychiatric ratings were performed on seven schizophrenic patients (mean age = 41.4 years) who had been examined 18 years previously in a study that used similar psychiatric ratings and a comparable rCBF technique. Neither the clinical symptomatology nor the rCBF level and distribution had changed appreciably between 1972 and 1990. The findings indicate that cerebral functional activity in chronic schizophrenia remains constant in spite of continuous neuroleptic medication.
Cantor-Graae
E
E
Department of Psychogeriatrics, St. Lars Hospital, Lund, Sweden.
Warkentin
S
S
Franzén
G
G
Risberg
J
J
Ingvar
D H
DH
D000328:Adult; D000368:Aged; D001143:Arousal / Q000502:physiology; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000098:blood supply* / Q000000981:diagnostic imaging; D002908:Chronic Disease; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D005625:Frontal Lobe / Q000098:blood supply / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011877:Radionuclide Imaging; D012039:Regional Blood Flow / Q000502:physiology; D012559:Schizophrenia / Q000175:diagnosis / Q000000981:diagnostic imaging*; D012565:Schizophrenic Psychology; D014980:Xenon Radioisotopes
D014980:Xenon Radioisotopes