[The inhibition of endothelial cell proliferation by esters of 4-aminomethylbenzoic acid (pamba)].
PAMBA-esters are able to decrease the proliferation of in vitro cultivated endothelial cells. PAMBA-hexylester was found to be the most effective one. In comparison to PAMBA-ethylester the ethylesters of EACA, 4-amino-benzoic acid, 4-amidinobenzoic acid and 4-amidino-phenylpyruvic acid were investigated.
Beyer
S
S
Fachrichtung Pharmazie, Ernst-Moritz-Arndt-Universität Greifswald.
Pilgrim
H
H
D010129:4-Aminobenzoic Acid / Q000494:pharmacology; D062365:Aminobenzoates / Q000494:pharmacology; D000818:Animals; D000933:Antifibrinolytic Agents / Q000494:pharmacology*; D002417:Cattle; D002455:Cell Division / Q000187:drug effects; D003864:Depression, Chemical; D004730:Endothelium, Vascular / Q000166:cytology* / Q000187:drug effects; D013329:Structure-Activity Relationship; D062366:para-Aminobenzoates
D062365:Aminobenzoates; D000933:Antifibrinolytic Agents; D062366:para-Aminobenzoates; C015668:4-aminomethylbenzoic acid; D010129:4-Aminobenzoic Acid
Die Hemmung der Endothelzellproliferation durch Ester der 4-Aminomethylbenzoesäure (PAMBA).