[Effects of green tea extract on the development of aflatoxin B1-induced precancerous enzyme-altered hepatocellular foci in rats].
Three kinds of extracts of green tea (decoction extract of green tea, water extract of green tea and ethanol extract of green tea) were tested for their effects on aflatoxin B1 (AFB1)-induced hepatocarcinogenesis in rats. The results revealed that all these three extracts of green tea possessed the remarkable inhibitory effects on the development of precancerous enzyme-altered hepatocellular foci. These results indicated that the main components of the green tea responsible for cancer prevention were all soluble in water and ethanol and thus providing an important clue for the search of the effective components in green tea for cancer prevention.
Qin
G Z
GZ
Department of Pathology, Guangxi Cancer Institute, Nanning.
D016604:Aflatoxin B1; D000818:Animals; D006651:Histocytochemistry; D008114:Liver Neoplasms, Experimental / Q000139:chemically induced / Q000188:drug therapy*; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use*; D011230:Precancerous Conditions / Q000139:chemically induced / Q000188:drug therapy*; D051381:Rats; D011919:Rats, Inbred Strains; D013662:Tea
D010936:Plant Extracts; D013662:Tea; D016604:Aflatoxin B1