[The effect of polyanion, cationic and anionic dyes and nonelectrolytes on phagosome fusion with lysosomes in mouse peritoneal macrophages].
Polyanion (mannansulphate), cation dyes (Toluidine blue, Nile blue), anion-dye (Trypan blue) also non-electrolytes (urea, glutaraldehyde) were found to inhibit the phagosome-lysosome fusion in murine macrophages. The mechanism of this effect is discussed.
Mozhenok
T P
TP
Bulychev
A G
AG
Braun
A D
AD
D000818:Animals; D000838:Anions; D002412:Cations; D002478:Cells, Cultured / Q000187:drug effects / Q000648:ultrastructure; D004396:Coloring Agents / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004573:Electrolytes / Q000494:pharmacology*; D008247:Lysosomes / Q000187:drug effects* / Q000648:ultrastructure; D008264:Macrophages / Q000187:drug effects* / Q000648:ultrastructure; D051379:Mice; D008856:Microscopy, Fluorescence; D010529:Peritoneal Cavity / Q000166:cytology; D010588:Phagosomes / Q000187:drug effects* / Q000648:ultrastructure; D013997:Time Factors
D000838:Anions; D002412:Cations; D004396:Coloring Agents; D004573:Electrolytes
Vliianie polianiona, kationnykh i anionnykh krasiteleĭ i neélektrolitov na sliianie fagosom s lizosomami v peritoneal'nykh makrofagakh mysheĭ.