High grade atrioventricular heart block in 2 adults with systemic lupus erythematosus.
We describe 2 patients with systemic lupus erythematosus (SLE) and high grade atrioventricular (AV) block. In one patient anti-Ro antibodies were positive. This antibody has been associated with congenital complete heart block in children of mothers with SLE; however, its role in adult high grade AV block is not clear. We reviewed the 8 published cases of adults with SLE and high grade AV block. The possible mechanisms that could be implicated in the pathology of high grade AV block are discussed.
Martinez-Costa
X
X
Department of Internal Medicine, Hospital General Vall d'Hebron, Barcelona, Spain.
Ordi
J
J
Barberá
J
J
Selva
A
A
Bosch
J
J
Vilardell
M
M
D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D004562:Electrocardiography; D005260:Female; D006327:Heart Block / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*
D000974:Antibodies, Antinuclear; C035356:SS-A antibodies