A case of neurogenic orthostatic hypertension.
A patient with orthostatic hypertension of neurogenic origin is reported. The Schellong and head-up tilt tests produced a sudden moderate to marked increase of the blood pressure, but the plasma renin activity and plasma aldosterone level showed a normal response. The cold pressor test also produced a moderate to marked increase in the blood pressure. Pharmacological cardiovascular autonomic nervous function tests showed a decrease of parasympathetic tone and denervation hypersensitivity of the sympathetic nerve terminals. These findings suggest that the orthostatic hypertension in this patient was mainly due to sympathetic denervation hypersensitivity.
Araki
K
K
Third Department of Internal Medicine, Kyoto Prefectural University of Medicine, Japan.
Ueda
Y
Y
Kono
I
I
Ookawara
T
T
Kashima
K
K
D000311:Adrenal Glands / Q000378:metabolism; D000368:Aged; D000450:Aldosterone / Q000097:blood; D001342:Autonomic Nervous System Diseases / Q000097:blood / Q000175:diagnosis*; D001794:Blood Pressure; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D009638:Norepinephrine; D012083:Renin / Q000032:analysis
D000450:Aldosterone; D012083:Renin; D009638:Norepinephrine