An aberrant hemolysin of Vibrio cholerae non-O1.
An aberrant hemolysin produced by a Vibrio cholerae non-O1 strain N037 (N037-hly) was purified and characterized. N037-Hly was antigenically very similar to El Tor hemolysin but differed in molecular weight (48,000 vs. 60,000), interaction with glucose, and hemolytic activity. Of 100 V. cholerae non-O1 strains other than the N037 strain examined, none produced this aberrant hemolysin. The N-terminal amino acid sequence of N037-hly was highly homologous to that of El Tor hemolysin.
Iwanaga
M
M
Department of Bacteriology, University of the Ryukyus School of Medicine, Okinawa, Japan.
Ichinose
Y
Y
D000595:Amino Acid Sequence; D001483:Base Sequence; D002772:Cholera Toxin / Q000276:immunology; D006460:Hemolysin Proteins / Q000737:chemistry* / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification; D006461:Hemolysis; D008969:Molecular Sequence Data; D012689:Sequence Homology, Nucleic Acid; D014734:Vibrio cholerae / Q000737:chemistry* / Q000235:genetics / Q000472:pathogenicity
D006460:Hemolysin Proteins; D002772:Cholera Toxin