Tightly coupled respiration in rat brain homogenates.
"Respiratory control", a typical feature of well coupled mitochondria, was found to be higher in rat brain homogenate than in isolated mitochondria. This observation points to the possibility of studying the coupling between respiration and ADP phosphorylation, as well as mitochondrial metabolism, directly in homogenates and not in isolated mitochondria, using very small samples of brain tissue.
Tiałowska
B
B
Department of Bioenergetics, Jedrzej Sniadecki, Academy of Physical Education, Gdańsk-Oliwa, Poland.
Kaczor
J
J
Stempak
W
W
Gryboś
D
D
Popinigis
J
J
D000244:Adenosine Diphosphate / Q000494:pharmacology; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D004579:Electron Transport; D008928:Mitochondria / Q000378:metabolism; D010085:Oxidative Phosphorylation / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D014475:Uncoupling Agents / Q000494:pharmacology
D014475:Uncoupling Agents; D000244:Adenosine Diphosphate