title: Common bile duct obstruction in cystic fibrosis: utility of hepatobiliary scintigraphy.
abstract: Abdominal pain occurs commonly in patients with cystic fibrosis, and is the result of a variety of causes, including hepatobiliary disorders. With the increasing duration of survival in these patients, diagnostic investigations for abdominal pain, including hepatobiliary scanning, may be utilized more frequently than in the past. Difficulties in the interpretation of scintigraphic studies may arise because of associated gallbladder anomalies that occur in more than 50% of patients with cystic fibrosis. Hypoplasia of the gallbladder (microgallbladder) occurs commonly. A case is presented in which Tc-99m disofenin hepatobiliary scanning proved diagnostic in a patient with cystic fibrosis and cholelithiasis leading to common bile duct obstruction. The hepatobiliary abnormalities and causes of common bile duct obstruction encountered in cystic fibrosis are reviewed.
authors.affiliation: Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor.
authors.forename: L M
authors.initials: LM
authors.lastname: Fig
authors.forename: D
authors.initials: D
authors.lastname: Daugherty
authors.forename: T
authors.initials: T
authors.lastname: Nostrant
authors.forename: B
authors.initials: B
authors.lastname: Shapiro
mesh_terms: D015746:Abdominal Pain / Q000000981:diagnostic imaging / Q000209:etiology; D000328:Adult; D002779:Cholestasis / Q000000981:diagnostic imaging* / Q000209:etiology; D003137:Common Bile Duct Diseases / Q000000981:diagnostic imaging* / Q000209:etiology; D003550:Cystic Fibrosis / Q000150:complications* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007098:Imino Acids; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D019785:Technetium Tc 99m Disofenin
chemical_list: D007098:Imino Acids; D015609:Organotechnetium Compounds; D019785:Technetium Tc 99m Disofenin