[Clinical comparative study of local anesthetics. Random double blind study with four commercial preparations].
In a randomized double blind study effects and tolerability of the local anesthetics Prilocaine 3% with Felypressin, Articaine 4% with Epinephrine 1/200,000 and 1/100,000, and Lidocaine 2% with Epinephrine 1/100,000 were tested. There was no significant difference between the four agents as far as effect on blood pressure, pulse, and tissue rehabilitation are concerned. Prilocaine can be used for extractions and surgical tooth removal. It can not be recommended for apicoectomy or implantation. The better results of Articaine 4% compared to Lidocaine 2% were statistically not significant.
Khoury
F
F
Klinik und Poliklinik für Mund-, und Kiefer-Gesichtschirurgie der Westfalischen Wilhelms-Universität Munster.
Hinterthan
A
A
Schürmann
J
J
Arns
H
H
D000779:Anesthetics, Local / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects; D002355:Carticaine / Q000494:pharmacology; D004311:Double-Blind Method; D004837:Epinephrine / Q000494:pharmacology; D005259:Felypressin / Q000494:pharmacology; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008012:Lidocaine / Q000494:pharmacology; D010147:Pain Measurement; D011318:Prilocaine / Q000494:pharmacology; D014945:Wound Healing / Q000187:drug effects
D000779:Anesthetics, Local; D011318:Prilocaine; D005259:Felypressin; D008012:Lidocaine; D002355:Carticaine; D004837:Epinephrine
Klinische Vergleichsuntersuchung von Lokalanästhetika. Eine randomisierte Doppelblindstudie mit vier Handelspräparaten.