Structure-based inhibition of HIV-1 protease activity and viral infectivity.
DeCamp
D L
DL
Department of Pharmaceutical Chemistry, University of California, San Francisco 94143-0446.
Babé
L M
LM
Furth
P
P
Ortiz de Montellano
P
P
Kuntz
I D
ID
Craik
C S
CS
D001665:Binding Sites; D002402:Cathepsin D / Q000037:antagonists & inhibitors; D016333:HIV Protease / Q000737:chemistry; D017320:HIV Protease Inhibitors; D015497:HIV-1 / Q000187:drug effects* / Q000201:enzymology / Q000502:physiology; D006220:Haloperidol / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D015394:Molecular Structure; D011480:Protease Inhibitors / Q000494:pharmacology; D014779:Virus Replication / Q000187:drug effects; D000092502:Renin Inhibitors
D002402:Cathepsin D; D016333:HIV Protease; D017320:HIV Protease Inhibitors; D006220:Haloperidol; D011480:Protease Inhibitors; D000092502:Renin Inhibitors