[The experimental transplacental passage of dimethylformamide and toluene].
The author presents data on the transplacental passage of dimethylformamide (DMFA) and toluene in combined exposure at the level of the maximum allowable concentrations. A new method for measurements of chemicals in animal biomedia is suggested. The permeability index for DMFA has made up 37.1%, that for toluene 90.2%. The results recommend the new method for experimental and clinical measurements of chemicals.
Shumilina
A V
AV
D000280:Administration, Inhalation; D000818:Animals; D002849:Chromatography, Gas; D004126:Dimethylformamide / Q000032:analysis / Q000493:pharmacokinetics*; D005260:Female; D005333:Fetus / Q000737:chemistry / Q000378:metabolism; D010920:Placenta / Q000737:chemistry / Q000378:metabolism*; D011247:Pregnancy; D051381:Rats; D014050:Toluene / Q000032:analysis / Q000493:pharmacokinetics*
D014050:Toluene; D004126:Dimethylformamide
Izuchenie transplatsentarnogo perekhoda dimetilformamida i toluola v éksperimente.