Photodegradation of nalidixic and tiaprofenic acids and nifedipine in aerobic conditions.
Since nalidixic acid had been previously studied in acidic and basic media, nifedipine had been investigated in anaerobic conditions and under ultraviolet light and tiaprofenic acid had not been studied at all, their photodegradation was carried out in this laboratory under milder conditions, with methanol as the solvent and using visible light. The role of oxygen was demonstrated and the photoproducts were isolated and identified spectroscopically.
Vargas
F
F
Centro de Química, Instituto Venezolano de Investigaciones Científicas, Caracas.
Rivas
C
C
Machado
R
R
Miranda
M A
MA
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000528:radiation effects*; D006801:Humans; D009268:Nalidixic Acid / Q000737:chemistry / Q000528:radiation effects*; D009543:Nifedipine / Q000528:radiation effects*; D010100:Oxygen; D010787:Photosensitivity Disorders / Q000139:chemically induced; D011422:Propionates / Q000737:chemistry / Q000528:radiation effects*; D013057:Spectrum Analysis
D000894:Anti-Inflammatory Agents, Non-Steroidal; D011422:Propionates; C021270:tiaprofenic acid; D009268:Nalidixic Acid; D009543:Nifedipine; D010100:Oxygen