title: A clinical profile of multidrug resistant typhoid fever.
abstract: Fifty blood culture positive patients of typhoid fever were studied during the current outbreak of the disease for their clinical profile. In 39 (78%) cases the isolates of S. typhi were resistant to conventional drugs. Children below 2 years of age constituted 20% of the total cases and belonged exclusively to the group with multidrug resistant typhoid fever (MRTF). The clinical presentation seemed to mimic malaria, bronchopneumonia, meningitis, etc. Typhoid hepatitis was diagnosed in 2 cases with MRTF. Life threatening complications were seen in 28.2% patients and were observed exclusively in MRTF group.
authors.affiliation: Department of Pediatrics, Lady Hardinge Medical College, New Delhi.
authors.forename: S
authors.initials: S
authors.lastname: Mishra
authors.forename: A K
authors.initials: AK
authors.lastname: Patwari
authors.forename: V K
authors.initials: VK
authors.lastname: Anand
authors.forename: P K
authors.initials: PK
authors.lastname: Pillai
authors.forename: S
authors.initials: S
authors.lastname: Aneja
authors.forename: J
authors.initials: J
authors.lastname: Chandra
authors.forename: D
authors.initials: D
authors.lastname: Sharma
mesh_terms: D002648:Child; D002675:Child, Preschool; D004352:Drug Resistance, Microbial; D006801:Humans; D008826:Microbial Sensitivity Tests; D012485:Salmonella typhi / Q000187:drug effects*; D014435:Typhoid Fever / Q000188:drug therapy* / Q000382:microbiology