title: Structure and synthesis of nectrisine, a new immunomodulator isolated from a fungus.
abstract: The structure of a novel immunomodulator, nectrisine (1), has been elucidated on the basis of chemical and spectroscopic evidence. Its absolute stereochemistry was predicted on the basis of the dibenzoate chirality rule and finally confirmed by a synthesis from D-glucose.
authors.affiliation: Exploratory Research Laboratories, Fujisawa Pharmaceutical Co., Ltd., Ibaraki, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kayakiri
authors.forename: K
authors.initials: K
authors.lastname: Nakamura
authors.forename: S
authors.initials: S
authors.lastname: Takase
authors.forename: H
authors.initials: H
authors.lastname: Setoi
authors.forename: I
authors.initials: I
authors.lastname: Uchida
authors.forename: H
authors.initials: H
authors.lastname: Terano
authors.forename: M
authors.initials: M
authors.lastname: Hashimoto
authors.forename: T
authors.initials: T
authors.lastname: Tada
authors.forename: S
authors.initials: S
authors.lastname: Koda
mesh_terms: D000276:Adjuvants, Immunologic / Q000138:chemical synthesis* / Q000302:isolation & purification / Q000494:pharmacology; D006999:Hypocreales / Q000737:chemistry*; D050113:Imino Furanoses; D011759:Pyrrolidines / Q000138:chemical synthesis* / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D000276:Adjuvants, Immunologic; D050113:Imino Furanoses; D011759:Pyrrolidines; C055825:nectrisine