A device for experimental radiosurgery.
As radiosurgery evolves into a widely available treatment modality for a variety of intracranial lesions, the need for basic research concerning the radiobiology of high-dose single-fraction ionizing radiation becomes crucial. A device especially designed for experimental radiosurgery in the cat is described. It incorporates basic parts of the Kopf stereotactic frame for accurate target positioning. A motorized pendular movement of the machine is used to describe a radiation arc, while the radiation source (either a linear accelerator or a cobalt machine) remains stationary. The pathway of the different radiation arcs is modified by rotation of the animal platform around the machine isocenter. Mechanical accuracy tests have shown a maximal alignment error of 0.15 mm, comparing favorably with that reported for modern clinical radiosurgical systems.
Bova
F
F
Department of Radiation Oncology, University of Florida, Gainesville.
Spiegelmann
R
R
Friedman
W A
WA
D000818:Animals; D002415:Cats; D003037:Cobalt Radioisotopes; D004867:Equipment Design; D010315:Particle Accelerators / Q000295:instrumentation*; D016634:Radiosurgery / Q000295:instrumentation*
D003037:Cobalt Radioisotopes