Diaphragmatic electromyogram power-spectral analysis as a function of reduced end-expiratory lung volume.
We examined the centroid frequency (Fc) of the electromyogram power-frequency spectra from the costal (EMGco) and crural (EMGcr) diaphragms at functional residual capacity and at reduced end-expiratory lung volume (EELV) (induced by abdominal banding) in six anesthetized newborn piglets. EMGco and EMGcr were recorded from bipolar electrodes embedded in the costal and crural diaphragms respectively. A fast Fourier transformation of ECG free EMGco and EMGcr was used to compute the power-frequency spectra and calculate the Fc of EMGco and EMGcr. The nitrogen washout technique was used to measure EELV. Abdominal banding induced a reduction in EELV of 30.6% functional residual capacity (range 22-39%). The mean Fc of EMGcr was not significantly altered by the reduction in EELV, whereas the mean Fc of the EMGco fell in every animal at reduced EELV by 13 +/- 8% of baseline Fc (p less than 0.05). We conclude that alterations in lung volume alone can determine changes in the EMGco power spectrum and Fc. Investigators performing EMGco power spectral analysis should consider EELV status when interpreting their findings.
Lantzy
A
A
Department of Pediatrics, University of Pittsburgh School of Medicine, Magee-Womens Hospital, Pennsylvania 15213.
O'Day
T L
TL
Vazquez
R L
RL
Guthrie
R D
RD
Watchko
J F
JF
D000818:Animals; D000831:Animals, Newborn; D003964:Diaphragm / Q000502:physiology*; D004576:Electromyography; D005221:Fatigue / Q000503:physiopathology; D005652:Functional Residual Capacity; D008176:Lung Volume Measurements; D009119:Muscle Contraction / Q000502:physiology; D015656:Respiratory Mechanics / Q000502:physiology*; D013552:Swine