title: [Biometric parameters of the uterus and ovaries in sheep after administration of Depotocin inj. Spofa in early puerperium].
abstract: Objectivisation of the physiological course of puerpery and control of involution processes of uterus represent topical questions of an increased frequency of lambing. Our study was directed at the determination of the weight, length of body and horns of uterus as well as of the weight, length, width and height of ovaries, following the administration of carbetocin (Depotocin inj. Spofa), in the puerperal period of Slovak Merino sheep. The study was aimed at obtaining objective biometric data on uterus and ovaries and recording the influence of carbetocin on the involution of uterus and ovaries of sheep. Thirty ewes, divided into two groups, were included in the experiment. The animals of the experimental group (n = 15) were subjected to treatment with carbetocin (Depotocin inj. Spofa) at the amount 2 x 0.07 mg. The first dose was applied intramuscularly (i. m.) on the 2nd day after parturition and the second dose was injected subcutaneously (s.c.) on the 4th day after lambing. The second group (n = 15) served as a control. Three ewes (n = 3) were bled on each of the following days: 1, 7, 17, 25 and 34 after parturition. After bleeding the sexual organs were removed by excision and their weight and the length of the body and horns of uterus and of ovaries was determined. The number and size of follicles were determined on the surface of ovaries. The weight of uterus body showed a declining tendency in sheep of the control group with a statistically significant decrease from the 17th till the 34th day after parturition (P less than 0.01). Its weight varied from 56.0-14.6 to 5.2-0.3 g in the above-mentioned time interval. The experimental group showed a statistically significant decrease in weight as early as on the 7th day after lambing compared to the 1st day after parturition, down to the values 185.66-38.91 g (P less than 0.05). The decrease in the weight of uterus body recorded on day 17 (106.56-41.08 g) was less pronounced than in the control group. The final average weight of the body of uterus on the 34th day after parturition was 41.36-8.52 g, that means higher than in the control group (5.2-0.3 g). The weight of gravid horns in the experimental group declined significantly as early as on the 7th day after parturition to the average weight of 60.89-9.45 g and reached 9.86-3.49 g on the 34th day.(ABSTRACT TRUNCATED AT 400 WORDS)
authors.affiliation: Ustav experimentálnej veterinárnej medicíny, Kosice.
authors.forename: M
authors.initials: M
authors.lastname: Krajnicáková
authors.forename: J
authors.initials: J
authors.lastname: Elecko
authors.forename: E
authors.initials: E
authors.lastname: Bekeová
authors.forename: I
authors.initials: I
authors.lastname: Maracek
authors.forename: V
authors.initials: V
authors.lastname: Hendrichovský
mesh_terms: D000818:Animals; D001699:Biometry; D005260:Female; D010053:Ovary / Q000033:anatomy & histology / Q000187:drug effects*; D010120:Oxytocics / Q000494:pharmacology*; D010121:Oxytocin / Q000031:analogs & derivatives* / Q000494:pharmacology; D049590:Postpartum Period; D012756:Sheep / Q000033:anatomy & histology*; D014599:Uterus / Q000033:anatomy & histology / Q000187:drug effects*
chemical_list: D010120:Oxytocics; D010121:Oxytocin; C020731:carbetocin
vernacular_title: Biometrické parametre maternice a vajecníkov po aplikácii Depotocinu inj. Spofa v ranom puerpériu oviec.