Effects of nucleus basolateralis amygdalae neurotoxic lesions on some spontaneous activities in the rat.
Drinking, feeding, locomotion and exploratory activity of male Wistar rats were assessed after bilateral stereotaxic administration of ibotenic acid in the nucleus basolateralis amygdalae. Feeding, drinking and locomotion were measured in an activity cage, while exploratory activity was determined in a multiple Y-maze. In the 24-hour cycle, lesioned animals exhibited unvaried feeding, decreased drinking and increased locomotion. Exploration was also increased. The results show that this nucleus is not involved in quantitative feeding control, while it does exert a significant facilitatory influence on drinking. It also exerts an inhibitory influence on exploration and on locomotion.
Ambrogi Lorenzini
C
C
Dipartimento di Scienze Fisiologiche, Firenze, Italy.
Baldi
E
E
Bucherelli
C
C
Giachetti
A
A
Tassoni
G
G
D000679:Amygdala / Q000033:anatomy & histology / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D001479:Basal Ganglia / Q000033:anatomy & histology / Q000187:drug effects / Q000502:physiology*; D001522:Behavior, Animal / Q000187:drug effects*; D004327:Drinking Behavior / Q000187:drug effects; D005106:Exploratory Behavior / Q000187:drug effects; D005247:Feeding Behavior / Q000187:drug effects; D007051:Ibotenic Acid / Q000633:toxicity; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D009412:Nerve Fibers / Q000187:drug effects; D009457:Neuroglia / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains
D007051:Ibotenic Acid