[Characteristics of functional activity of thrombocytes in patients with "aspirin" bronchial asthma].
Upon comparison of functional activity of platelets and their response to aspirin in 20 subjects with aspirin bronchial asthma, 19 patients with non-aspirin bronchial asthma and 21 healthy controls it was found out that in aspirin asthma platelet count is elevated, their response to aggregation inductors enhances while to aspirin is abnormal, plasmic thromboxane level is reduced. Aspirin asthma patients are believed to have a specific platelet defect.
Evsiukova
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EV
D001241:Aspirin / Q000009:adverse effects* / Q000494:pharmacology; D001249:Asthma / Q000097:blood* / Q000139:chemically induced; D011464:Epoprostenol / Q000097:blood; D006801:Humans; D066298:In Vitro Techniques; D010974:Platelet Aggregation / Q000187:drug effects* / Q000502:physiology; D010976:Platelet Count / Q000187:drug effects; D010979:Platelet Function Tests; D013268:Stimulation, Chemical; D013928:Thromboxane A2 / Q000097:blood
D013928:Thromboxane A2; D011464:Epoprostenol; D001241:Aspirin
Osobennosti funktsional'noĭ aktivnosti trombotsitov u bol'nykh "aspirinovoi" bronkhial'noĭ astmoĭ.