[Hemo-rheologic disorders as risk factors of ischemic cerebral infarction].
The problem of blood rheological abnormalities as risk factors for ischaemic stroke is only incompletely known. The blood rhreological++ parameters were measured in 35 patients with ischaemic stroke (groups: CS--completed stroke, TIA/RIND--transient brain ischaemia or reversible ischaemic neurological deficit) in the first 48 hours after the onset of the disease and then, for control, after 2-3 weeks. Persistence of abnormal rheological parameters of blood was observed, with increased plasma viscosity, reduced plasticity of erythrocytes, higher fibrinogen level, and increased erythrocyte aggregation 2-3 weeks after the onset of acute ischaemic stroke, which suggests their role as possible risk factors. In the group with completed stroke a significant increase of erythrocyte aggregation was noted 2-3 weeks after disease onset which may be connected with increased absorption of fibrinogen molecules on erythrocyte cell membrane.
Kowal
P
P
Katedry i Kliniki Neurologii AM, Poznaniu.
D000368:Aged; D001809:Blood Viscosity / Q000502:physiology*; D002545:Brain Ischemia / Q000097:blood* / Q000150:complications; D002544:Cerebral Infarction / Q000097:blood / Q000209:etiology*; D004903:Erythrocyte Aggregation / Q000502:physiology*; D005260:Female; D005340:Fibrinogen / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012039:Regional Blood Flow; D012307:Risk Factors
D005340:Fibrinogen
Zaburzenia hemoreologiczne jako czynniki ryzyka niedokrwiennego udaru mózgu.