[Efficiency of enterosorbents and detoxication mechanisms in immature rats with simulated hepatitis].
Different modifications of fibrous enterosorbent of the ACFM "Dnepr-MN" type exert a normalizing effect on the morphofunctional state of the liver of preadolescent rats with the model of toxic hepatitis. The distortion in the oxidation of lipids with peroxide and in the antioxidizing system protection removed, antitoxic liver function increases, which is confirmed by microsomal oxidation processes. A mediated effect of enterosorbents on the hepatocyte membrane structures is very significant for their detoxication effect.
Tarakhovskiĭ
M L
ML
Tsypkun
A G
AG
Sergeev
V P
VP
Zadorozhnaia
T D
TD
Tishchenko
V K
VK
Litvinov
V F
VF
D000818:Animals; D056486:Chemical and Drug Induced Liver Injury / Q000503:physiopathology / Q000628:therapy*; D004195:Disease Models, Animal; D016061:Enterosorption / Q000379:methods*; D015227:Lipid Peroxidation / Q000187:drug effects; D008862:Microsomes, Liver / Q000187:drug effects; D010084:Oxidation-Reduction; D051381:Rats; D012741:Sexual Maturation / Q000502:physiology*
Effektivnost' énterosorbentov i mekhanizmy detoksikatsii pri modelirovannom gepatite u nepolovozrelykh krys.