[Changes in serotonin-containing EC-cells in the lamina epithelialis mucosae of the small intestine in young children with growth disorders caused by intestinal diseases].
Duodenal jejunal biopsy material from children with growth retardation due to enteric disease was investigated. The disease dependent mucosa types were classified into three groups according to Shmerling (1970). 5-hydroxytryptamine was demonstrated with an impregnation technique and histochemically, as well, in EC-cells in the crypt epithelium. The EC-cell content in specimens with subtotal villus atrophy (type III) was higher significantly compared to normal mucosa (type I). The findings were discussed with regard to the possible role of 5-hydroxytryptamine in the pathogenesis of the growth retardation due to enteric disease in children.
Pfister
C
C
Institut für Anatomie, Medizinische Fakultät (Charité), Humboldt-Universität zu Berlin.
Peuthert
R
R
Günther
M
M
Schön
E
E
D001706:Biopsy; D002675:Child, Preschool; D004702:Endocrine Glands / Q000737:chemistry* / Q000166:cytology; D005260:Female; D006130:Growth Disorders / Q000209:etiology*; D006801:Humans; D007223:Infant; D007410:Intestinal Diseases / Q000150:complications* / Q000473:pathology; D007413:Intestinal Mucosa / Q000737:chemistry* / Q000166:cytology; D007421:Intestine, Small / Q000737:chemistry* / Q000166:cytology; D008297:Male; D012701:Serotonin / Q000032:analysis*
D012701:Serotonin
Veränderungen Serotonin-haltiger EC-Zellen in der Lamina epithelialis mucosae des Dünndarmes bei Kleinkindern mit enteral bedingten Gedeihstörungen.