A new active steroidal saponin from Anemarrhena asphodeloides.
A new active steroidal saponin, anemarsaponin B, was isolated from the rhizomes of Anemarrhina asphodeloides. The structure of anemarsaponin B was elucidated as 26-O-beta-D-glucopyranosylfurost-20(22)-ene-3 beta, 26-diol-3-O-beta-D-glucopyranosyl-(1----2)-beta-D-galactopyranoside by chemical and spectral studies. Preliminary pharmacological tests showed that anemarsaponin B could inhibit PAF-induced rabbit platelet aggregation in vitro.
Dong
J X
JX
School of Pharmacy, Second Military Medical University, Shanghai, People's Republic of China.
Han
G Y
GY
D000818:Animals; D002240:Carbohydrate Sequence; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000494:pharmacology; D005260:Female; D008297:Male; D008969:Molecular Sequence Data; D015394:Molecular Structure; D010975:Platelet Aggregation Inhibitors / Q000302:isolation & purification* / Q000494:pharmacology; D011817:Rabbits; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014315:Triterpenes
D004365:Drugs, Chinese Herbal; D010975:Platelet Aggregation Inhibitors; D012503:Saponins; D014315:Triterpenes; C073427:anemarsaponin B