Examination of the choice of models for computing the extracellular potential of a single fibre in a restricted volume conductor.
The paper compares the rigorous and the conventional approximate line source solution of Laplace's equation used to evaluate the potential of a single cylindrical fibre. Particular attention is given to the solutions for a radially restricted circular cylindrical volume conductor. The effect of the extent of the volume conductor b on the difference between the potentials evaluated according to the different models is examined. For values of b larger than 10 times the fibre radius, the relative difference is less than 1 per cent and the values of b around 2 times the fibre radii, the error reaches as much as 17 per cent.
Trayanova
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National Science Foundation, Engineering Research Center, Durham, North Carolina.
Henriquez
C S
CS
D000200:Action Potentials / Q000502:physiology; D006801:Humans; D008433:Mathematics; D008959:Models, Neurological; D009474:Neurons / Q000502:physiology*