title: Primary amyloidosis with dry eyes and dry mouth--a case report.
abstract: We report a rare case of dry eyes and dry mouth caused by primary amyloidosis. A 66-year-old woman with keratoconjunctivitis sicca and xerostomia died of acute respiratory failure. Shirmer's test, gum test, and sialography indicated Sjögren's syndrome. Lip biopsy revealed amyloid deposition around the salivary ducts. Bence-Jones protein was noted in the urine. At autopsy, amyloid deposition was identified histochemically in many organs, mainly on the vessel walls. Primary amyloidosis should be considered as a differential diagnosis of Sjögren's syndrome.
authors.affiliation: Department of Internal Medicine, Miki City Hospital, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Itoh
authors.forename: S
authors.initials: S
authors.lastname: Ohashi
authors.forename: T
authors.initials: T
authors.lastname: Tsujino
authors.forename: M
authors.initials: M
authors.lastname: Takenaka
authors.forename: H
authors.initials: H
authors.lastname: Kodama
authors.forename: M
authors.initials: M
authors.lastname: Kishihara
authors.forename: T
authors.initials: T
authors.lastname: Inatome
authors.forename: T
authors.initials: T
authors.lastname: Inoh
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007638:Keratoconjunctivitis Sicca / Q000209:etiology*; D012859:Sjogren's Syndrome / Q000175:diagnosis; D014987:Xerostomia / Q000209:etiology*