In vivo behaviour of low molecular weight iron complexes.
The in vivo distribution in mice of ferric citrate, ferric beta-glycerophosphate and ferric lactate complexes has been studied. There is a relationship between the 59Fe uptake by various tissues and the physicochemical characteristics of the complexes. Ferric lactate seems a useful preparation for iron deficiency therapy.
Anghileri
L J
LJ
Biophysics Laboratory, Medicine Faculty, University of Nancy, France.
Cordova Martinez
A
A
Maincent
P
P
Robert
J
J
D000818:Animals; D001842:Bone and Bones / Q000378:metabolism; D004334:Drug Administration Schedule; D005290:Ferric Compounds / Q000008:administration & dosage / Q000493:pharmacokinetics*; D005994:Glycerophosphates / Q000008:administration & dosage / Q000493:pharmacokinetics*; D006863:Hydrogen-Ion Concentration; D007274:Injections, Intraperitoneal; D007275:Injections, Intravenous; D007668:Kidney / Q000378:metabolism; D007773:Lactates / Q000008:administration & dosage / Q000493:pharmacokinetics*; D019344:Lactic Acid; D008099:Liver / Q000378:metabolism; D051379:Mice; D008970:Molecular Weight; D013154:Spleen / Q000378:metabolism
D005290:Ferric Compounds; D005994:Glycerophosphates; D007773:Lactates; D019344:Lactic Acid; C025314:ferric citrate; C031463:beta-glycerophosphoric acid