Stereotypy and asymmetry in mice.
Mice ran in a circular runway. Number and direction of circuits were recorded. Most control mice ran about the same number of circuits in each direction. After 100 mumols/kg cocaine there were 3.5 times as many circuits and most mice ran most circuits in one direction. Some mice ran strongly in one direction after a first dose of cocaine and strongly in the other direction after a second dose. Hence, the primary influence toward unidirectional running is stereotypy rather than asymmetry.
Dews
P B
PB
Laboratory of Psychobiology, Harvard Medical School, Boston, MA.
D000818:Animals; D003042:Cocaine / Q000494:pharmacology*; D005260:Female; D007839:Functional Laterality; D008297:Male; D051379:Mice; D009043:Motor Activity; D012016:Reference Values; D013239:Stereotyped Behavior / Q000187:drug effects
D003042:Cocaine