title: T2-weighted three-dimensional MP-RAGE MR imaging.
abstract: The application of three-dimensional (3D) magnetization-prepared rapid-gradient-echo (MP-RAGE) imaging to the acquisition of T2-weighted 3D data sets has been investigated, with a 90 degrees x-180 degrees y-90 degrees-x pulse set (driven equilibrium) for the T2 contrast preparation. A theoretical model was used to study the contrast behavior of brain tissue. The effects of radio-frequency and static-field inhomogeneities and eddy currents on the T2 contrast preparation and the effects of eddy currents on the gradient-echo acquisition resulted in blurring and intensity banding artifacts. With a multistep gradient preparation, these artifacts could be suppressed. With further development, this technique may yield a clinically practical method for obtaining T2-weighted 3D data sets of relatively large volumes (eg, the whole head) suitable for multiplanar reformatting.
authors.affiliation: Department of Radiology, University of Virginia Health Sciences Center, Charlottesville 22908.
authors.forename: J P
authors.initials: JP
authors.lastname: Mugler
authors.forename: T A
authors.initials: TA
authors.lastname: Spraggins
authors.forename: J R
authors.initials: JR
authors.lastname: Brookeman
mesh_terms: D016477:Artifacts; D001921:Brain / Q000033:anatomy & histology; D002555:Cerebrospinal Fluid; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008280:Magnetics; D012212:Rheology; D012815:Signal Processing, Computer-Assisted