title: [Endocarditis caused by Candida parapsilosis after total correction of tetralogy of Fallot. Medico-surgical treatment].
abstract: Three children with Candida Parapsilosis endocarditis after total surgical correction for Tetralogy of Fallot, are reported. Blood cultures became negative in one child with amphotericin-B and in the other two with Ketoconazole, before reoperation for septal patch replacement. Oral therapy with Ketoconazole continued for a total of 24 months, and during a mean follow-up of 36 months no side effects or reinfection occurred. Medical and surgical conjoined therapy, with surgical timing decided on clinical and laboratorial grounds, were important for good results and cure.
authors.affiliation: Serviço de Cardiologia Pediátrica, Hospital de Santa Marta, Lisboa.
authors.forename: A
authors.initials: A
authors.lastname: Macedo
authors.forename: A
authors.initials: A
authors.lastname: Agualusa
authors.forename: S
authors.initials: S
authors.lastname: Kaku
authors.forename: M
authors.initials: M
authors.lastname: Lima
authors.forename: J
authors.initials: J
authors.lastname: Cabrita
authors.forename: R
authors.initials: R
authors.lastname: Bento
authors.forename: F
authors.initials: F
authors.lastname: Sampayo
mesh_terms: D002177:Candidiasis / Q000628:therapy*; D003131:Combined Modality Therapy; D004696:Endocarditis / Q000382:microbiology / Q000628:therapy*; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007654:Ketoconazole / Q000627:therapeutic use; D011183:Postoperative Complications / Q000382:microbiology*; D013771:Tetralogy of Fallot / Q000601:surgery*
chemical_list: D007654:Ketoconazole
vernacular_title: Endocardite por Cândida parapsilosis após correcção total de tetralogia de Fallot. Tratamento médico-cirúrgico.