Cyclosporin in steroid-resistant auto-immune haemolytic anaemia.
A case of Evans' syndrome which was refractory to conventional and high dose steroid treatment and to splenectomy was treated with cyclosporin, beginning with the dose of 10 mg/kg/day and then gradually tapering to 4 mg/kg/day. The patient experienced excellent benefit from cyclosporin; his haematological parameters were completely normal at the 12th month of therapy, without any side effect of the drug.
Dündar
S
S
Hacettepe University, School of Medicine Department of Haematology, Ankara, Turkey.
Ozdemir
O
O
Ozcebe
O
O
D000284:Administration, Oral; D000305:Adrenal Cortex Hormones / Q000037:antagonists & inhibitors*; D000328:Adult; D000744:Anemia, Hemolytic, Autoimmune / Q000097:blood / Q000188:drug therapy*; D001803:Blood Transfusion; D003131:Combined Modality Therapy; D016572:Cyclosporine / Q000008:administration & dosage*; D004351:Drug Resistance; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D012074:Remission Induction; D013156:Splenectomy; D013577:Syndrome
D000305:Adrenal Cortex Hormones; D016572:Cyclosporine