The hypoglycemic effect of "Hipogalegin".
In alloxan-induced diabetes in rats a marked increase in fasting glycemia was seen. The administration of "Hipogalegin" (0.45 g/kg b.w.; for one administration) led to a marked decrease of the glycemia in fasted diabetic animals: 40% of the diabetic animals subjected to this treatment survived and continued to survive even on the 94th day after diabetes was induced. Diabetic animals who were not given "Hypogalegin" died during the first two weeks after diabetes was induced.
Coprean
D
D
Biological Research Center Cluj-Napoca, Romania.
Giurgea
R
R
Tamaş
M
M
Roşca
M
M
Coprean
D
D
Cuparencu
B
B
D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000188:drug therapy*; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D051381:Rats; D011919:Rats, Inbred Strains
D007004:Hypoglycemic Agents; D010936:Plant Extracts; C075093:hypogalegin