[The ability of partusisten to improve kidney excretory function in the initial stage of kidney failure in patients with chronic glomerulonephritis].
To assess the effect of partusisten (fenoterol) on excretory function of the kidneys, the drug was administered per os in a dose of 10 mg/day for 7-10 days in 17 chronic glomerulonephritis patients with initial forms (stages I-IIA) of renal failure. A dramatic increase of glomerular filtration, a certain rise of tubular reabsorption, a reduction of blood concentration of nitrous residues were revealed, which was accompanied by electrolyte shifts and hemodynamic changes characteristic of partusisten. It is concluded that partusisten can be used as a drug ameliorating excretory function of the kidneys in chronic glomerulonephritis patients with initial forms of chronic renal failure.
Skipskiĭ
I M
IM
Komandenko
M S
MS
Shulutko
B I
BI
Zamoskovskaia
G A
GA
D000293:Adolescent; D000328:Adult; D002908:Chronic Disease; D004341:Drug Evaluation; D005260:Female; D005280:Fenoterol / Q000627:therapeutic use*; D005921:Glomerulonephritis / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007668:Kidney / Q000187:drug effects* / Q000503:physiopathology; D007676:Kidney Failure, Chronic / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged
D005280:Fenoterol
Sposobnost' partusistena uluchshat' ékskretornuiu funktsiiu pochek pri nachal'noĭ pochechnoĭ nedostatochnosti u bol'nykh khronicheskim glomerulonefritom.