[Effect of kang shuai shen fang on immune functions of 60Co gamma-ray irradiated mice].
In this paper we reported that kang shuai shen fang (KSSF) could recover the immune functions of irradiated mice. The results indicated that KSSF is able to enhance the proliferation response of spleen cells of irradiated mice to Con A and LPS. At the dosage of 400 mg/kg.d, KSSF can stimulate the production of plaque forming cells, the DTH response induced by allogeneic splenocytes. The mixed lymphocyte reaction was much stronger in the drug-receiving irradiated group than that in the control group. Further study indicated that KSSF is able to enhance the production of interleukin 2 in irradiated mice.
Gong
P
P
Department of Immunology, Beijing Medical University.
D000818:Animals; D000921:Antibody-Producing Cells / Q000187:drug effects*; D002455:Cell Division / Q000187:drug effects; D003037:Cobalt Radioisotopes; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D006462:Hemolytic Plaque Technique; D007376:Interleukin-2 / Q000378:metabolism; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D011833:Radiation Injuries, Experimental / Q000276:immunology*; D013154:Spleen / Q000166:cytology
D003037:Cobalt Radioisotopes; D004365:Drugs, Chinese Herbal; D007376:Interleukin-2