[Cytochemical manifestations of short- and long-term activation of the dopaminergic system of the rat brain].
In order to find correlation between changes in morpho-chemical characteristics of neurons of certain brain structures and changes of the functional state of rats with high horizontal motional activity in "open field" under activation of dopaminergic system caused by short-term and long-term L-DOPA injection aminopeptidase activity and protein content were studied. It was shown that in spite of similar effects of short- and long-term injection on the behaviour of animals, the nature of morpho-chemical changes in the brain differs significantly depending on the duration of the drug injection.
Gershteĭn
L M
LM
Chebotareva
T L
TL
Sergutina
A V
AV
D000626:Aminopeptidases / Q000032:analysis; D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D006651:Histocytochemistry; D007980:Levodopa / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D009419:Nerve Tissue Proteins / Q000032:analysis; D009474:Neurons / Q000187:drug effects; D051381:Rats; D013997:Time Factors
D009419:Nerve Tissue Proteins; D007980:Levodopa; D000626:Aminopeptidases
Tsitokhimicheskie proiavleniia kratkovremennoĭ i dlitel'noĭ aktivatsii dofaminergicheskoĭ sistemy mozga krys.