title: Anti-spermatogenic effect of Vinca rosea Linn.
abstract: Regressive changes in seminiferous tubules and Leydig cells, increased cholesterol content in testis, and degeneration of all germinal elements other than spermatogonia were observed in the male Swiss albino mice, treated with aqueous extract of V. rosea leaves for 24 days. While the results reflect antiandrogenic and antispermatogenic action of V. rosea, the selective retention of the spermatogonia provides scope for the much desired revival of spermatogenesis on cessation of the treatment.
authors.affiliation: PG Department of Zoology, Jamal Mohamed College, Tiruchirapalli, India.
authors.forename: T
authors.initials: T
authors.lastname: Murugavel
authors.forename: M A
authors.initials: MA
authors.lastname: Akbarsha
mesh_terms: D000818:Animals; D000988:Antispermatogenic Agents / Q000494:pharmacology*; D008297:Male; D051379:Mice; D014748:Vinca Alkaloids / Q000494:pharmacology*
chemical_list: D000988:Antispermatogenic Agents; D014748:Vinca Alkaloids