title: [Creatine phosphokinase in leptospirosis].
abstract: Leptospirosis is a widely-distributed infectious disease, that usually presents with fever, headache and myalgia. Organ involvement could have very different severity degree. We evaluate 21 patients with leptospirosis looking for prognostic and diagnostic value of myalgia and/or elevated creatine-phosphokinase serum levels. Myalgia was recorded in nearly all patients (91%). Creatine-phosphokinase levels above normal limits were seen in 37% of cases, either in severe forms of leptospirosis with organ involvement or in mild forms of disease. We conclude that creatine-phosphokinase elevated levels could be of early diagnosis interest but they are not solely seen in the more severe forms of the disease.
authors.affiliation: Servicio de Medicina Interna, Hospital Verge de la Cinta, Tortosa, Tarragona.
authors.forename: A
authors.initials: A
authors.lastname: Grau
authors.forename: T
authors.initials: T
authors.lastname: Pumarola
authors.forename: J L
authors.initials: JL
authors.lastname: Llort
authors.forename: M J
authors.initials: MJ
authors.lastname: Murria
authors.forename: D
authors.initials: D
authors.lastname: Bofill
authors.forename: J
authors.initials: J
authors.lastname: Manresa
authors.forename: I
authors.initials: I
authors.lastname: Piñas
authors.forename: J
authors.initials: J
authors.lastname: Giné
mesh_terms: D000293:Adolescent; D000328:Adult; D003402:Creatine Kinase / Q000097:blood*; D005334:Fever / Q000209:etiology; D006261:Headache / Q000209:etiology; D006801:Humans; D007922:Leptospirosis / Q000097:blood / Q000150:complications / Q000201:enzymology*; D008297:Male; D009135:Muscular Diseases / Q000209:etiology; D010146:Pain / Q000209:etiology; D011379:Prognosis
chemical_list: D003402:Creatine Kinase
vernacular_title: Creatinfosfocinasa en la leptospirosis.