title: [Nature of female sterility in mutants at the ecs locus controlling sensitivity to ecdysterone in Drosophila melanogaster].
abstract: Using interstrain level ovary transplantations function of ovaries was estimated in females bearing mutations at the ecs locus mapped in the 2B3-5 region of the X-chromosome of Drosophila melanogaster. Dissection of recipient flies and genetic analysis of their progeny demonstrated that the donor ovary in fertile flies was capable of normal functioning in the case of connection of the donor ovary in fertile flies with the recipient oviducts. Therefore, female-sterile mutations at the ecs locus are somatic line specific. SDS-PAGE electrophoresis revealed normal level of the yolk proteins in such females. Thus, the sterility of the ecs mutants may arise from abnormal morphogenesis of their genital disc, due to the loss of normal sensitivity to ecdysterone.
authors.forename: O M
authors.initials: OM
authors.lastname: Mazina
authors.forename: S E
authors.initials: SE
authors.lastname: Korochkina
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D004331:Drosophila melanogaster / Q000235:genetics*; D004441:Ecdysterone / Q000502:physiology*; D004527:Egg Proteins / Q000032:analysis; D005260:Female; D005298:Fertility / Q000235:genetics; D009024:Morphogenesis / Q000235:genetics; D009154:Mutation / Q000235:genetics; D010053:Ovary / Q000502:physiology / Q000637:transplantation
chemical_list: D004527:Egg Proteins; D004441:Ecdysterone
vernacular_title: Issledovanie prirody steril'nosti samok u mutantov po lokusu ecs, kontroliruiushchemu chuvstvitel'nost' k ekdisteronu u Drosophila melanogaster.