[Hyposplenism in celiac disease. Role of a gluten-free diet].
Hyposplenism is a common complication of adult celiac disease. A study of splenic function in 17 adult patients with celiac disease was performed both before and during treatment with a gluten-free diet. Splenic hypofunction was assessed evaluating morphological changes in red cells (Howell-Jolly bodies, spherocytosis, achantocytosis). The hyposplenic changes were compared with: age of patients, duration of symptoms previous to diagnosis, severity of the clinical picture and histological response to treatment. We concluded that 82.4% of patients had hyposplenic changes and that there was a non significant tendency to improve such changes by a strict adherence to gluten-free diet.
Vázquez
H
H
Sección Intestino Delgado, Hospital Nacional de Gastroenterología, Buenos Aires, Argentina.
Martínez
C
C
Xavier
L
L
Mazure
R
R
Boerr
L
L
Bai
J
J
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002446:Celiac Disease / Q000097:blood / Q000150:complications* / Q000178:diet therapy; D002648:Child; D004912:Erythrocytes / Q000473:pathology; D005260:Female; D005983:Glutens / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D013158:Splenic Diseases / Q000097:blood / Q000209:etiology*
D005983:Glutens
Hipoesplenia en la enfermedad celíaca. Rol de la dieta libre de glúten.