Biologically active constituents of Arnebia euchroma: structures of new monoterpenylbenzoquinones: arnebinone and arnebifuranone.
Two quinonic compounds, arnebinone and arnebifuranone, were isolated from the roots of Arnebia euchroma and their structures were elucidated on the basis of spectral evidence. Arnebionone is a monoterpenyl-benzoquinone in which the monoterpene moiety forms a fused ring to the benzoquinone. Arnebifuranone is another monoterpenylbenzoquinone with a furan ring containing side chain which is bonded to the benzoquinone at the head carbon of C10 moiety originating from the geranyl moiety of geranylhydroquinone.
Yao
X S
XS
Faculty of Pharmaceutical Sciences, University of Tokyo, Japan.
Ebizuka
Y
Y
Noguchi
H
H
Kiuchi
F
F
Shibuya
M
M
Iitaka
Y
Y
Seto
H
H
Sankawa
U
U
D000818:Animals; D016227:Benzoquinones / Q000032:analysis* / Q000494:pharmacology; D003864:Depression, Chemical; D005663:Furans / Q000032:analysis* / Q000494:pharmacology; D066298:In Vitro Techniques; D007679:Kidney Medulla / Q000187:drug effects / Q000378:metabolism; D009285:Naphthoquinones / Q000032:analysis* / Q000494:pharmacology; D010936:Plant Extracts / Q000032:analysis; D010946:Plants, Medicinal / Q000737:chemistry*; D011453:Prostaglandins / Q000096:biosynthesis*; D011817:Rabbits
D016227:Benzoquinones; D005663:Furans; D009285:Naphthoquinones; D010936:Plant Extracts; D011453:Prostaglandins; C073510:arnebinone; C073511:arnebifuranone