Secondary prevention of myocardial reinfarction with low dose aspirin.
A clinical trial of secondary prevention of reinfarction with low dose aspirin is reported. 50 mg aspirin per day was administered in 216 case. 211 cases did not take aspirin or any other antiplatelet agents as a control group. The follow-up periods in the two groups were 19.4 +/- 12.6 mon and 20.7 +/- 13.0 mon, respectively. There were 175 males in the aspirin group and 137 males in the control group. The incidence of reinfarction was reduced by 65% and platelet aggregation was inhibited obviously in the aspirin group as compared to the control group in men, whereas no significant trends were observed in women.
Chen
Z
Z
Cardiovascular Institute, CAMS, Beijing.
Xu
Y
Y
Yu
Q
Q
Kou
W
W
Lu
Z
Z
Yao
K
K
Gao
R
R
Chen
J
J
Jia
Y
Y
Duan
B
B
D000368:Aged; D001241:Aspirin / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000517:prevention & control*; D010974:Platelet Aggregation / Q000187:drug effects; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology; D012008:Recurrence; D012737:Sex Factors
D010975:Platelet Aggregation Inhibitors; D001241:Aspirin