title: Intraplacental sonolucent spaces: incidences and relevance to chorionic villus sampling.
abstract: Detailed ultrasound examination of the placentae from 293 consecutive women requesting first-trimester chorionic villus sampling (CVS) showed evidence of intraplacental sonolucent spaces with varying density in 42.3 per cent of these placentae. Their presence, however, did not complicate the subsequent course of these women's pregnancies. Their prime significance relates to CVS, where inadvertent entry into these areas can lead to bleeding and contamination of the villus specimens with blood. A search for these spaces should be made before sampling, and when present, they should be avoided wherever possible.
authors.affiliation: Department of Obstetrics and Gynaecology, City Hospital, Nottingham, U.K..
authors.forename: D T
authors.initials: DT
authors.lastname: Liu
authors.forename: R
authors.initials: R
authors.lastname: Agbaje
authors.forename: C
authors.initials: C
authors.lastname: Preston
authors.forename: J
authors.initials: J
authors.lastname: Savage
mesh_terms: D015193:Chorionic Villi Sampling / Q000009:adverse effects / Q000379:methods; D005260:Female; D006801:Humans; D010920:Placenta / Q000166:cytology* / Q000000981:diagnostic imaging; D011247:Pregnancy; D011256:Pregnancy Outcome; D011261:Pregnancy Trimester, First; D014463:Ultrasonography