A method to optimize the design parameters of sustained release preparations.
A procedure is proposed for optimizing the design parameters of a drug, which exhibits n-exponential disposition kinetics, intended as an oral sustained release product. The product comprises two components, an immediately available dose and a portion released at a constant rate.
Cadorniga
R
R
Departamento de Farmacia y Tecnologia Farmaceutica, Facultad de Farmacia, U.C.M. Madrid, España.
Frutos
G
G
Martin
P J
PJ
D002626:Chemistry, Pharmaceutical; D003692:Delayed-Action Preparations / Q000737:chemistry*; D008962:Models, Theoretical; D010599:Pharmacokinetics
D003692:Delayed-Action Preparations