title: Immunocytochemistry of eruptive haemangiomas (pyogenic granulomas).
abstract: Eight eruptive haemangiomas (pyogenic granulomas) were stained immunocytochemically. Many of the cells reacted with markers for endothelial cells. The reactions with anti-vWF antibody were weaker than those with UEA-I-lectin and with the monoclonal antibody BMA 120. These results probably reflect reduced capability for storage of vWF by proliferating endothelial cells. Many cells were negative for endothelial-cell markers, and they reacted with a monoclonal antibody against muscle actin. These cells may be myofibroblasts and pericytes. The studies indicate that eruptive haemangiomas are composed of pericytes, myofibroblasts and endothelial cells.
authors.affiliation: Department of Dermatology and Andrology, Justus-Liebig University, Giessen, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Weyers
authors.forename: J U
authors.initials: JU
authors.lastname: Alles
mesh_terms: D006391:Hemangioma / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D012878:Skin Neoplasms / Q000473:pathology*