title: [Studies on the cell and tissue tolerance of a polymeric bone replacement material].
abstract: BOP (Biocompatible Osteoconductive Polymer) shows no cytotoxicity in vitro. After six months of subcutaneous implantation in mice a weak cellular tissue reaction is seen histologically. The hard tissue reaction after six months of implantation in fractured tibia bone shows less connective tissue between the implant material BOP and bone.
authors.affiliation: Klinik für Zahnarztliche Prothetik der RWTH Aachen.
authors.forename: M
authors.initials: M
authors.lastname: Augthun
authors.forename: R
authors.initials: R
authors.lastname: Bilo
authors.forename: S
authors.initials: S
authors.lastname: Hauptmann
authors.forename: H
authors.initials: H
authors.lastname: Richter
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000633:toxicity*; D001842:Bone and Bones / Q000187:drug effects; D003238:Connective Tissue / Q000187:drug effects; D004285:Dogs; D005260:Female; D008768:Methylmethacrylates / Q000633:toxicity*; D051379:Mice; D008807:Mice, Inbred BALB C; D011205:Povidone / Q000633:toxicity*; D019736:Prostheses and Implants / Q000009:adverse effects*
chemical_list: D001672:Biocompatible Materials; D008768:Methylmethacrylates; C037334:poly(methylmethacrylate-N-vinylpyrrolidone); D011205:Povidone
vernacular_title: Untersuchungen zur Zell- und Gewebeverträglichkeit eines Knochenersatzmaterials auf Polymerbasis.