[The dynamics of the Zn content in the pancreatic islets of rabbits after the administration of the diabetogenic agent dithizone].
The dynamics of changes of the Zn content in the pancreatic islets of rabbits after dithizon injection was studied. The amount of this metal in the islets reduced due to destruction of the cells and under the effect of high blood plasma glucose concentration. The insulin producing cells were devoid of zinc in diabetes of long duration with high hyperglycemia.
Gol'dberg
E D
ED
Eshchenko
V A
VA
Bovt
V D
VD
D000634:Aminoquinolines; D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000139:chemically induced / Q000378:metabolism; D004230:Dithizone / Q000494:pharmacology*; D005456:Fluorescent Dyes; D006651:Histocytochemistry; D007515:Islets of Langerhans / Q000187:drug effects* / Q000378:metabolism; D011817:Rabbits; D013449:Sulfonamides; D013997:Time Factors; D014105:Tosyl Compounds; D015032:Zinc / Q000032:analysis*
D000634:Aminoquinolines; D005456:Fluorescent Dyes; D013449:Sulfonamides; D014105:Tosyl Compounds; C031480:8-(4-tolylsulfonylamino)quinoline; D004230:Dithizone; D015032:Zinc
Dinamika soderzhaniia Zn v pankreaticheskikh ostrovkakh krolikov posle vvedeniia diabetogennogo agenta ditizona.