title: [Changes in cognitive functions after sleep deprivation as a prognostic indicator of drug therapy of endogenous depression].
abstract: Studies performed on a group of 27 patients with endogenous depression demonstrated that changes of cognitive functions following sleep deprivation may reveal a prognostic potential for results of pharmacological treatment of depression. Worsening of memory following sleep deprivation was more frequently observed in a subgroup of nonresponders. Greater improvement of concentration and increased task mobilization were noticed in a subgroup which positively responded to the antidepressant treatment. Patient's age, sex, self-rating of depression intensity or baseline level of ability to memorize, to concentrate attention, to perform tasks did not exhibit any predictive value.
authors.affiliation: II Kliniki Psychiatrycznej Instytutu Psychiatrii i Neurologii.
authors.forename: W
authors.initials: W
authors.lastname: Walecka
authors.forename: E
authors.initials: E
authors.lastname: Habrat
mesh_terms: D000328:Adult; D000368:Aged; D000929:Antidepressive Agents, Tricyclic / Q000627:therapeutic use*; D001288:Attention / Q000187:drug effects / Q000502:physiology*; D003866:Depressive Disorder / Q000188:drug therapy / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008568:Memory / Q000187:drug effects / Q000502:physiology*; D008875:Middle Aged; D011379:Prognosis; D011581:Psychological Tests / Q000379:methods; D012074:Remission Induction; D012892:Sleep Deprivation / Q000502:physiology*
chemical_list: D000929:Antidepressive Agents, Tricyclic
vernacular_title: Zmiany funkcji poznawczych po deprywacji snu jako wskaźnik prognostyczny farmakoterapii depresji endogennej.