title: Effect of general anaesthesia on the pharynx.
abstract: Conventional lateral radiography was used in 18 elderly male patients to investigate the changes induced by general anaesthesia in the upper airway. The effect of tongue traction under anaesthesia was studied similarly in another 11 patients. Following induction of anaesthesia, there were highly significant approximations to the posterior pharyngeal wall of the soft palate (median change 1.3 mm, 95% confidence interval (Cl) 0.3-2.6 mm; P = 0.006), tongue base (mean change 6.5 mm, 95% Cl 5.3-7.7 mm; P less than 0.001) and epiglottis (mean change 3.8 mm, 95% Cl 3.1-4.5 mm; P less than 0.001). Apparent radiographic occlusion of the airway occurred most consistently at the level of the soft palate (17 of 18 patients), sometimes at the level of the epiglottis (four patients), but the tongue base did not touch the posterior pharyngeal wall in any patient. Traction on the tongue failed to clear the nasopharyngeal obstruction. Attempted inspiration under anaesthesia caused major secondary collapse of the pharynx, with multiple sites of obstruction, similar to that found in obstructive sleep apnoea.
authors.affiliation: Division of Anaesthesia, Northwick Park Hospital, Harrow, Middlesex.
authors.forename: P R
authors.initials: PR
authors.lastname: Nandi
authors.forename: C H
authors.initials: CH
authors.lastname: Charlesworth
authors.forename: S J
authors.initials: SJ
authors.lastname: Taylor
authors.forename: J F
authors.initials: JF
authors.lastname: Nunn
authors.forename: C J
authors.initials: CJ
authors.lastname: Doré
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000402:Airway Obstruction / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D000768:Anesthesia, General / Q000009:adverse effects*; D004825:Epiglottis / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010160:Palate, Soft / Q000000981:diagnostic imaging / Q000503:physiopathology; D010614:Pharynx / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011859:Radiography; D014059:Tongue / Q000000981:diagnostic imaging / Q000503:physiopathology