Pattern of NADPH-diaphorase active neurons in rat forebrain is unchanged after pentylenetetrazol kindling.
The activity of NADPH-diaphorase in rat telencephalic structures has been revealed by use of a histochemical method. Multiple neurons belonging to different nuclei were found to contain the enzyme. Furthermore, diaphorase reactive nerve fibres and terminal fields were observed to be widely distributed throughout rat brain. Chemical kindling induced by pentylenetetrazol (PTZ) did not effect the regional distribution and cellular localization of the enzyme in the rat CNS.
Seidel
I
I
Department of Neuromorphology, Institute of Neurobiology and Brain Research, Magdeburg, Germany.
Bernstein
H G
HG
Becker
A
A
Grecksch
G
G
Luppa
H
H
Müller
M
M
D000818:Animals; D006651:Histocytochemistry; D007696:Kindling, Neurologic; D008297:Male; D009252:NADPH Dehydrogenase / Q000378:metabolism*; D009474:Neurons / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D010433:Pentylenetetrazole / Q000494:pharmacology*; D016548:Prosencephalon / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D012640:Seizures / Q000201:enzymology
D009252:NADPH Dehydrogenase; D010433:Pentylenetetrazole