Cerebral blood flow velocity in term infants treated with phototherapy.
The relationship between phototherapy and changes in the cerebral circulation was studied in 50 jaundiced newborn infants. The aim of the study was to determine whether important alterations in cerebral hemodynamic occur under blue light therapy. Blood flow velocity, i.e., the pulsatility index (PI) and the area under the velocity curve (AUVC), was measured in the anterior cerebral arteries (ACA) using a Duplex scan technique. No prominent changes compromise flow in the ACA. PI and AUVC values were similar during and after phototherapy (p greater than 0.5) suggesting effective cerebral autoregulation in term infants undergoing light treatment for hyperbilirubinemia.
Amato
M
M
Department of Pediatrics, Children's Hospital, Aarau, Switzerland.
Donati
F
F
D002536:Cerebral Arteries / Q000502:physiology; D002560:Cerebrovascular Circulation / Q000502:physiology*; D006801:Humans; D006932:Hyperbilirubinemia / Q000150:complications / Q000628:therapy; D007231:Infant, Newborn; D010789:Phototherapy / Q000009:adverse effects*; D011673:Pulsatile Flow / Q000502:physiology