[Aggregation of denatured membrane proteins--the initial stage of acid hemolysis].
Influence of some sulfhydryl reagents on kinetics of acid hemolysis has been investigated. The results obtained indicate that the mechanism of acid hemolysis includes aggregation of some denatured membrane integral proteins, following the intermolecular disulfide bond formation. A suggestion is made that in this hemolysis-inducing aggregation free SH-groups containing proteins only take place.
Ivanov
I T
IT
Benov
L Ts
LTs
D006461:Hemolysis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008565:Membrane Proteins / Q000378:metabolism*; D011489:Protein Denaturation; D013438:Sulfhydryl Compounds / Q000737:chemistry
D008565:Membrane Proteins; D013438:Sulfhydryl Compounds
Agregatsiia denaturirovannykh membrannykh belkov--nachal'nyĭ étap kislotnogo gemoliza.