Current progress on nucleoside antibiotics.
Structure and biological activity of thirty-six new nucleoside antibiotics which appeared after the 1988 review are described. New synthetic analogs of neplanocin and oxetanocin are also described with special emphasis on their antiviral activities. New biosynthetic findings on nikkomycins, blasticidin S, and griseolic acid are also reviewed.
Isono
K
K
Antibiotics Laboratory, RIKEN, Institute of Physical and Chemical Research, Saitama-ken, Japan.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification / Q000627:therapeutic use; D000903:Antibiotics, Antineoplastic / Q000737:chemistry / Q000302:isolation & purification / Q000627:therapeutic use; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000627:therapeutic use; D006801:Humans; D009705:Nucleosides / Q000737:chemistry / Q000302:isolation & purification / Q000627:therapeutic use; D013329:Structure-Activity Relationship
D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic; D000935:Antifungal Agents; D009705:Nucleosides