Effect of flavones and their metabolites on induction of SOS repair in the strain PQ37--E. coli K-12.
The SOS-Chromotest was used to detect DNA damage induced by two flavones: apigenin and luteolin and/or their metabolites. It was found that the compounds tested weakly induced the SOS repair system in the strain studied.
Czeczot
H
H
Department of Biochemistry, Medical School, Warszawa, Poland.
Bilbin
M
M
D000818:Animals; D001711:Biotransformation; D020843:Chamomile; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics*; D005419:Flavonoids / Q000378:metabolism / Q000494:pharmacology*; D047311:Luteolin; D008297:Male; D008862:Microsomes, Liver / Q000737:chemistry; D009822:Oils, Volatile / Q000494:pharmacology; D010946:Plants, Medicinal; D051381:Rats; D011919:Rats, Inbred Strains; D013014:SOS Response, Genetics / Q000187:drug effects*
D005419:Flavonoids; D009822:Oils, Volatile; D047311:Luteolin