Structural systematics of bioactive peptides and their biosynthetic implications.
Structures of natural peptides have been linearized according to their biosynthetic constructions. The structural diversities of these peptides originate from highly complex enzyme systems, that are often found to be integrated to polyenzymes. Polyenzymes are constructed from similar elements or modules, and structural variations can be understood from mutational events and rearrangements at the DNA-level.
von Doehren
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Institute of Biochemistry and Molecular Biology, Technical University Berlin.
D004798:Enzymes / Q000378:metabolism; D015394:Molecular Structure; D010452:Peptide Biosynthesis; D010455:Peptides / Q000737:chemistry* / Q000235:genetics; D012270:Ribosomes / Q000378:metabolism
D004798:Enzymes; D010455:Peptides