Isolation of an infectious oncogenic adenovirus strain from the stimulated lymphocytes of a patient with bladder tumour.
In attempts to grow viruses from tumour cells and circulating lymphocytes, we isolated an oncogenic infectious adenovirus type 18 strain from the phytohaemagglutinin-stimulated peripheral T-lymphocytes of a patient with bladder tumour. The virus genome is assumed to play certain role in the development of the tumour in interaction with other DNA viruses and the damaged immune system.
Kulcsár
G
G
Semmelweis University Medical School, István Hospital, Budapest.
Csata
S
S
Nász
I
I
D000260:Adenoviruses, Human / Q000302:isolation & purification* / Q000472:pathogenicity; D000368:Aged; D005260:Female; D006801:Humans; D009858:Oncogenic Viruses / Q000302:isolation & purification* / Q000472:pathogenicity; D010835:Phytohemagglutinins; D013601:T-Lymphocytes / Q000187:drug effects / Q000382:microbiology*; D014412:Tumor Virus Infections / Q000382:microbiology / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000382:microbiology* / Q000473:pathology; D014565:Urogenital Neoplasms / Q000382:microbiology
D010835:Phytohemagglutinins