[The evaluation of the efficacy of dalargin treatment in patients with face and neck phlegmons by the free-radical oxidation indices of the peripheral blood].
Dalargin was used in therapy of patients with phlegmons of the face and neck. The treatment efficacy was assessed by analyzing the parameters of the peripheral blood free-radical oxidation and clinical data. The main group (n = 38) patients with medium-severe or severe course of the process were administered dalargin as part of a therapeutic complex; such therapy resulted in early arrest of the inflammatory process and recovery of the reliable correlation between the major parameters of lipid peroxidation and antioxidant systems. These correlations were shifted in the reference group (26 patients), and inflammatory processes in the wound lasted longer in them.
Ganina
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SS
Ragimov
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ChR
D000293:Adolescent; D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000627:therapeutic use*; D002481:Cellulitis / Q000097:blood / Q000188:drug therapy*; D004341:Drug Evaluation; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005145:Face; D005260:Female; D005609:Free Radicals; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D009333:Neck
D000975:Antioxidants; D005609:Free Radicals; D016308:Enkephalin, Leucine-2-Alanine; C040996:enkephalin-Leu, Ala(2)-Arg(6)-
Otsenka éffektivnosti lecheniia dalarginom bol'nykh s flegmonami litsa i shei po pokazateliam svobodnoradikal'nogo okisleniia perifericheskoĭ krovi.