title: [Daunomycin and silicone oil in treatment of proliferative vitreoretinopathy].
abstract: We describe the long-term results after treatment of 68 eyes in advanced stages of proliferative vitreoretinopathy with vitrectomy, daunomycin perfusion, and silicone oil injection. Six reoperations were performed. After 18 months, 73% of the eyes showed no signs of retinal detachment and 89% had a visual acuity greater than 20/800. These results are better than those reported in previously published studies. Whether this improvement is due to the daunomycin treatment or to more aggressive surgical techniques, such as retinotomies, remains to be answered by a randomized trial.
authors.affiliation: Abteilung für Netzhaut- und Glaskörperchirurgie, Universitäts-Augenklinik, Bundesrepublik Deutschland.
authors.forename: P
authors.initials: P
authors.lastname: Wiedemann
authors.forename: C
authors.initials: C
authors.lastname: Leinung
authors.forename: R D
authors.initials: RD
authors.lastname: Hilgers
authors.forename: K
authors.initials: K
authors.lastname: Heimann
mesh_terms: D003131:Combined Modality Therapy; D003630:Daunorubicin / Q000008:administration & dosage*; D003930:Diabetic Retinopathy / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D011183:Postoperative Complications / Q000209:etiology; D015861:Retinal Neovascularization / Q000601:surgery*; D012827:Silicone Oils / Q000008:administration & dosage*; D014821:Vitrectomy / Q000379:methods*
chemical_list: D012827:Silicone Oils; D003630:Daunorubicin
vernacular_title: Daunomycin und Silikonöl bei der Behandlung der proliferativen Vitreoretinopathie.