[Distribution of lectin-receptors in normal, dysplastic and neoplastic cervical epithelium].
112 cases of normal, dysplastic and neoplastic cervical epithelium were studied with a panel of twelve various lectins and ABC technique. The results showed that: (1) ConA and WGA receptors were relative to Squamous epithelial origin of the Cervix. (2) PNA, UEA-1, BSL and PHA receptors correlated with the tumorigenicity of cervical squamous epithelium. (3) WGA receptor correlated with the cell differentiation of squamous carcinomas. (4) DBA receptor was related with tumor invasion. (5) ConA and SJA receptors were related to the tumorigenicity of columnar epithelium of the endocervical glands. (6) Applications of neuraminidase caused compositional changes of glycoconjugates in the receptors of normal, dysplastic and malignant cervical epithelium and this may be of some value in clinical practice.
Li
Z H
ZH
Department of Pathology, Xin Jiang Medical College.
D000230:Adenocarcinoma / Q000737:chemistry; D002278:Carcinoma in Situ / Q000737:chemistry; D002294:Carcinoma, Squamous Cell / Q000737:chemistry; D002584:Cervix Uteri / Q000378:metabolism*; D004848:Epithelium / Q000737:chemistry; D005260:Female; D006801:Humans; D011230:Precancerous Conditions / Q000737:chemistry; D011975:Receptors, Mitogen / Q000032:analysis*; D002578:Uterine Cervical Dysplasia / Q000378:metabolism*; D002583:Uterine Cervical Neoplasms / Q000737:chemistry*
D011975:Receptors, Mitogen