[Peritoneal mesothelioma and complete auriculo-ventricular block as late complications in Hodgkin's disease].
A patient who had been successfully treated of Hodgkin's disease (nodular sclerotic type) with mediastinal radiotherapy and polychemotherapy, suffered an acute pericarditis immediately after radiotherapy and a complete atrial-ventricular block 14 years later. Five years later she presented refractory hemorrhagic peritonitis. Necropsy study showed a peritoneal mesothelioma (in non radiated area) and diffuse subpericardial fibrosis. Complete A-V block is a very rare late complication of mediastinal radiotherapy and mesotheliomas (almost exclusively in irradiated areas), also. We have not found any reports on other cases of peritoneal mesotheliomas not attributable to radiotherapy as second neoplasia in Hodgkin's disease.
Ladero Quesada
J M
JM
Departamento de Medicina, Hospital Universitario de San Carlos, Madrid.
Amarillas Sánchez
L
L
Furió Bacete
V
V
Laredo Velasco
L
L
D005260:Female; D006327:Heart Block / Q000209:etiology* / Q000473:pathology; D006689:Hodgkin Disease / Q000150:complications* / Q000473:pathology / Q000532:radiotherapy; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary; D008207:Lymphatic Metastasis; D008654:Mesothelioma / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged; D010315:Particle Accelerators; D010534:Peritoneal Neoplasms / Q000209:etiology* / Q000473:pathology; D013997:Time Factors
Mesotelioma peritoneal y bloqueo aurículo-ventricular completo como complicaciones tardías de la enfermedad de Hodgkin.