title: The human genome: a view from above.
abstract: The genome of vertebrates (and of eukaryotes in general) is not simply formed by genes that are randomly scattered over vast expanses of "junk DNA", but is organized in a system which obeys precise rules, that amount to a genomic code. Moreover, genes are concentrated in the chromosomal regions which are the richest in G (guanine) and C (cytosine) and seem to correspond to the telomeric regions of certain chromosome arms (T-bands). The study of the genome organization in different vertebrate classes allowed us to approach in a novel way a number of fundamental problems of genome evolution.
authors.affiliation: Laboratoire de Génétique Moléculaire, Institut Jacques Monod, Paris, France.
authors.forename: G
authors.initials: G
authors.lastname: Bernardi
mesh_terms: D000818:Animals; D005075:Biological Evolution; D004247:DNA / Q000235:genetics; D005786:Gene Expression Regulation; D015894:Genome, Human; D006801:Humans; D014714:Vertebrates / Q000235:genetics
chemical_list: D004247:DNA