[Immunological change in pigmentary degeneration of retina and its relation to traditional Chinese medicine differentiation of syndromes].
Using monoclonal antibody technique, T lymphocyte cell subgroups, immunoglobins, complements, and circulating immune complexes (CIC) were measured in 60 patients with pigmentary degeneration of retina (RP) and 40 normal subjects. The results indicated that T1, T4, T8, C3 and C4 of the patients were lower than those of the controls; T4/T8, IgM and CIC of the patients were more than those of the controls. The differences between the patients and the controls were remarkably significant. Similarly, by investigating the objective quota of TCM differentiation of syndromes, the authors divided the RP patients into Liver-Kidney deficiency of Yin and Spleen-Kidney deficiency of Yang groups, and compared them with normal subjects. The results indicated that the two groups underwent similar change of immunology. But they had their own characteristics. The Yin-deficiency group showed remarkable increase of T4/T8 and normal T4; the Yang-deficiency group showed remarkable reduction of T1 and reduction of T4.
Qin
Y H
YH
Hunan Academy of TCM and Medicinal Herbs, Changsha.
Zhu
W F
WF
Li
C K
CK
D000293:Adolescent; D000328:Adult; D000936:Antigen-Antibody Complex / Q000378:metabolism; D016516:CD4-CD8 Ratio; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000378:metabolism; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D012162:Retinal Degeneration / Q000145:classification / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D016711:Yang Deficiency / Q000276:immunology; D016710:Yin Deficiency / Q000276:immunology
D000936:Antigen-Antibody Complex; D007075:Immunoglobulin M