title: [Isocapnic cold air provocation in healthy probands].
abstract: To study the physiological response to cold air challenge, the "flow-volume-loop" method was used. Fifty-one healthies (31 males and 20 females, mean age 30 +/- 9 years) served as the subjects. Measurements were done before and subsequently 5 and 30 min after challenge. In normal subjects it were observed both an increase and decrease of the airway obstruction. All registered changes were statistically significant. The range of normal alterations of parameters as a response to the cold air challenge was calculated on the base of obtained data.
authors.affiliation: Medizin-Ingenieurzentrum AEROSOL, Leningrad, UdSSR.
authors.forename: P P
authors.initials: PP
authors.lastname: Gorbenko
authors.forename: N A
authors.initials: NA
authors.lastname: Silber
authors.forename: E A
authors.initials: EA
authors.lastname: Melnikowa
mesh_terms: D000293:Adolescent; D000328:Adult; D000403:Airway Resistance / Q000502:physiology; D001249:Asthma / Q000503:physiopathology*; D016535:Bronchial Hyperreactivity / Q000503:physiopathology*; D001985:Bronchial Provocation Tests / Q000379:methods*; D002245:Carbon Dioxide / Q000097:blood*; D003080:Cold Temperature; D005260:Female; D006801:Humans; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D012123:Pulmonary Ventilation / Q000502:physiology; D012016:Reference Values
chemical_list: D002245:Carbon Dioxide
vernacular_title: Isokapnische Kaltluftprovokation bei gesunden Probanden.