Molecular modelling studies and the chromatographic behaviour of oxiracetam and some closely related molecules.
Modelling studies have been carried out on the cellulose-based chiral stationary phase used to separate the enantiomers of three simple lactams. These studies have helped in understanding differences in the chromatographic behaviour of these molecules.
Camilleri
P
P
SmithKline Beecham Ltd., Welwyn, Herts, U.K.
Murphy
J A
JA
Saunders
M R
MR
Thorpe
C J
CJ
D002240:Carbohydrate Sequence; D002482:Cellulose / Q000031:analogs & derivatives / Q000737:chemistry; D002845:Chromatography; D003199:Computer Systems; D008958:Models, Molecular; D008969:Molecular Sequence Data; D015394:Molecular Structure; D011619:Psychotropic Drugs / Q000737:chemistry / Q000302:isolation & purification; D011759:Pyrrolidines / Q000737:chemistry* / Q000302:isolation & purification*; D013237:Stereoisomerism
D011619:Psychotropic Drugs; D011759:Pyrrolidines; D002482:Cellulose; C040619:oxiracetam