Expression of chromosomal protein HMG-1 in transformed and normal human cells.
Western blot analysis showed differences in the expression of chromosomal high mobility group protein (HMG-1) in human leukemic cell lines and normal peripheral nonproliferating leukocytes. The amount of HMG-1 was increased in fast growing transformed cells. The data suggest that HMG-1 has an important function in cell proliferation.
Cabart
P
P
Institute of Hematology and Blood Transfusion, Prague, Czechoslovakia.
Kalousek
I
I
Jandová
D
D
D000911:Antibodies, Monoclonal / Q000096:biosynthesis; D015153:Blotting, Western; D002461:Cell Line, Transformed / Q000737:chemistry*; D002868:Chromosomal Proteins, Non-Histone / Q000032:analysis*; D006609:High Mobility Group Proteins / Q000032:analysis*; D006801:Humans; D007962:Leukocytes / Q000737:chemistry*; D012016:Reference Values
D000911:Antibodies, Monoclonal; D002868:Chromosomal Proteins, Non-Histone; D006609:High Mobility Group Proteins