title: Complete external ophthalmoplegia and asterixis with carbamazepine toxicity.
abstract: Ophthalmoplegia is a rarely observed sign in carbamazepine and other anticonvulsant overdoses. We present a patient who developed transient complete external ophthalmoplegia and asterixis with relative preservation of consciousness, in association with carbamazepine toxicity. Previously reported cases and proposed mechanisms are reviewed.
authors.affiliation: Department of Neurology, Royal Perth Hospital, WA.
authors.forename: K
authors.initials: K
authors.lastname: Ng
authors.forename: P L
authors.initials: PL
authors.lastname: Silbert
authors.forename: R H
authors.initials: RH
authors.lastname: Edis
mesh_terms: D002220:Carbamazepine / Q000009:adverse effects* / Q000037:antagonists & inhibitors / Q000097:blood; D004347:Drug Interactions; D062787:Drug Overdose; D004917:Erythromycin / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009886:Ophthalmoplegia / Q000097:blood / Q000139:chemically induced*; D011187:Posture; D014202:Tremor / Q000097:blood / Q000139:chemically induced*
chemical_list: D002220:Carbamazepine; D004917:Erythromycin