Usefulness of semi-quantitative cultures in the diagnosis of Clostridium difficile associated disease.
Semi-quantitative stool cultures on CCFA were compared to cytotoxic assays for the diagnosis of Clostridium difficile associated disease (CAD). There was a significant correlation between the amount of Clostridium difficile growth on CCFA, the presence of cytotoxin and a clinical diagnosis of CAD in the 541 initial stool specimens tested.
Poirier
L
L
Service de Microbiologie et Maladies Infectieuses, Hôpital Saint-Luc, Montreal, Quebec, Canada.
Lamothe
F
F
Vincelette
J
J
Bourgault
A M
AM
D001426:Bacterial Proteins; D001427:Bacterial Toxins / Q000032:analysis*; D001431:Bacteriological Techniques; D016360:Clostridioides difficile / Q000254:growth & development* / Q000302:isolation & purification; D003015:Clostridium Infections / Q000175:diagnosis / Q000382:microbiology*; D003603:Cytotoxins / Q000032:analysis*; D005243:Feces / Q000382:microbiology; D006801:Humans; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity
D001426:Bacterial Proteins; D001427:Bacterial Toxins; D003603:Cytotoxins; C031815:toxB protein, Clostridium difficile