Relationship between cows' milk consumption and incidence of IDDM in childhood.
OBJECTIVE
To compare age-standardized incidence rates of diabetes in children 0-14 yr of age and cows' milk consumption in various countries.


METHODS
Ecological correlation study. Only incidence rates from diabetes registries carefully validated by the Diabetes Epidemiology Research International Study Group were used-Finland, Sweden, Norway, Great Britain, Denmark, United States, New Zealand, Netherlands, Canada, France, Israel, and Japan. Data on fluid cows' milk consumption in corresponding countries were obtained from the International Dairy Federation.


RESULTS
Correlation between milk consumption and incidence of insulin-dependent diabetes mellitus (IDDM) was 0.96. The data fit a linear regression model, and analysis showed that 94% of the geographic variation in incidence might be explained by differences in milk consumption.


CONCLUSIONS
The results support the hypothesis that cows' milk may contain a triggering factor for the development of IDDM.
Dahl-Jørgensen
K
K
Aker Diabetes Research Center, Aker University Hospital, Oslo, Norway.
Joner
G
G
Hanssen
K F
KF
D000293:Adolescent; D000818:Animals; D002170:Canada / Q000453:epidemiology; D002417:Cattle; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000453:epidemiology*; D005060:Europe / Q000453:epidemiology; D005247:Feeding Behavior; D006801:Humans; D015994:Incidence; D007223:Infant; D007557:Israel / Q000453:epidemiology; D007564:Japan / Q000453:epidemiology; D008892:Milk; D009520:New Zealand / Q000453:epidemiology; D012042:Registries; D014481:United States / Q000453:epidemiology