[Prospective assessment of changes in microcirculation and central hemodynamics in patients with stable angina pectoris according to the data of radionuclide study methods].
The two-year follow-up of 102 patients aged 28-67 years who had Functional Classes I-III stable angina and took no regular antianginal therapy has demonstrated that the first deleterious changes occur in the vasodilator reserve of microcirculation. Then the capillary blood flow velocity decreases, whereas capillary permeability increases. Following 1.5 year of the follow-up there is a dramatic decline in cardiac output, coupled with a significant rise of total peripheral vascular resistance.
Atroshchenko
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D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002199:Capillary Permeability; D002302:Cardiac Output; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D011446:Prospective Studies; D011877:Radionuclide Imaging; D014655:Vascular Resistance; D014980:Xenon Radioisotopes
D014980:Xenon Radioisotopes
Prospektivnaia otsenka izmeneniĭ mikrotsirkuliatsii i tsentral'noĭ gemodinamiki u bol'nykh so stabil'noĭ stenokardieĭ po dannym radionuklidnykh metodov issledovaniia.