title: Automated microdensitometric quantification of bone ingrowth into porous implants.
abstract: The aim of this study was to develop a technique of automated histometric quantification of bone ingrowth into porous implant bodies that minimizes errors of volume determination arising from the section thickness of histologic specimens. A theoretical and experimental deduction is provided for the calculation of implant and bone layer thicknesses from the grey levels of microradiographs made from thick-section specimens. The presented method allows rapid raising of large amounts of histometric data when a computer-aided video system is available. A histologic preparation of specimens that permits the spatial reconstruction of the examined implant volume and analysis of three-dimensional distribution of bone ingrowth is suggested.
authors.affiliation: Department of Oral and Maxillofacial Surgery, University Medical School, Hannover, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Schliephake
authors.forename: D
authors.initials: D
authors.lastname: Klosa
authors.forename: F W
authors.initials: FW
authors.lastname: Neukam
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods*; D016301:Alveolar Bone Loss / Q000000981:diagnostic imaging*; D000818:Animals; D001861:Bone Regeneration; D015921:Dental Implants; D006882:Hydroxyapatites; D016348:Osseointegration; D011857:Radiographic Image Interpretation, Computer-Assisted; D013552:Swine; D013556:Swine, Miniature
chemical_list: D015921:Dental Implants; D006882:Hydroxyapatites