title: [Focal dystonias and facial hemispasm: treatment with botulinum A toxin].
abstract: We report the results of the treatment of 80 patients with various idiopathic focal dystonia and essential hemifacial spasm with Botulinum A toxin. A statistically significant improvement was obtained in our 34 patients with blepharospasm, 19 patients with hemifacial spasm, 59% of 22 patients with cervical dystonia and 60% of 5 patients with hand dystonia. Mean duration of the benefit of each injection was 15.3, 16.3, 7.6 and 8.7 weeks respectively. Adverse effects were local and transient. We concluded that botulinum A toxin is a safe and effective therapy for patients with focal dystonia and hemifacial spasm.
authors.affiliation: Servicio de Neurología, Fundación Jiménez Díaz, Madrid.
authors.forename: R
authors.initials: R
authors.lastname: Astarloa
authors.forename: B
authors.initials: B
authors.lastname: Morales
authors.forename: V
authors.initials: V
authors.lastname: Sánchez
authors.forename: N
authors.initials: N
authors.lastname: Peñafiel
authors.forename: J
authors.initials: J
authors.lastname: Rábano
authors.forename: J
authors.initials: J
authors.lastname: Oliván
authors.forename: J
authors.initials: J
authors.lastname: García de Yébenes
mesh_terms: D001764:Blepharospasm / Q000188:drug therapy*; D001905:Botulinum Toxins / Q000008:administration & dosage / Q000627:therapeutic use*; D005152:Facial Muscles / Q000187:drug effects; D006801:Humans; D007279:Injections, Subcutaneous; D013035:Spasm / Q000188:drug therapy*; D014103:Torticollis / Q000188:drug therapy*
chemical_list: D001905:Botulinum Toxins
vernacular_title: Distonías focales y hemiespasmo facial: tratamiento con toxina botulínica A.