title: [Blood lipoproteins in modeling of atherosclerosis and administration of protamine].
abstract: The influence of protamine on the HDL, LDL, VLDL species concentration variation as well as on their cholesterol and protein content in respect to total blood serum cholesterol in different periods (1 and 7 months) of hypercholesteremia in rabbits is investigated. Daily administration of protamine (10 mg/kg) during 30 days to intact animals did not change the investigated parameters. In the early period of hypercholesteremia protamine considerably increased the content of all lipoprotein fractions. Under the conditions of prolonged hypercholesteremia the LDL and VLDL concentrations decreased by 23 and 60 per cent, respectively; HDL increased by 101 per cent.
authors.forename: G Kh
authors.initials: GKh
authors.lastname: Bozhko
authors.forename: P V
authors.initials: PV
authors.lastname: Voloshin
authors.forename: T P
authors.initials: TP
authors.lastname: Boĭko
authors.forename: L S
authors.initials: LS
authors.lastname: Kostiukovskaia
mesh_terms: D000818:Animals; D001161:Arteriosclerosis / Q000097:blood* / Q000209:etiology; D002784:Cholesterol / Q000097:blood; D006937:Hypercholesterolemia / Q000097:blood / Q000150:complications; D008074:Lipoproteins / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D011479:Protamines / Q000008:administration & dosage / Q000494:pharmacology*; D011817:Rabbits; D013997:Time Factors
chemical_list: D008074:Lipoproteins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D011479:Protamines; D002784:Cholesterol
vernacular_title: Lipoproteiny krovi pri modelirovanii ateroskleroza i vvedenii protamina.