title: [Reference values and tolerance intervals].
abstract: Statistical aspects of tolerance intervals estimation are considered and tolerance coefficients for unilateral and central intervals are derived for normally distributed biological variables. The difference between confidence and tolerance interval is explained and application to biological and environmental monitoring, as well as applications to reference values estimation, are exemplified. Tables of unilateral and central coefficients are also produced and reported for different sample dimensions, confidence, and tolerance levels.
authors.affiliation: Istituto di Biometria e Statistica Medica, Università di Milano.
authors.forename: P
authors.initials: P
authors.lastname: Duca
mesh_terms: D004784:Environmental Monitoring / Q000592:standards*; D006801:Humans; D008954:Models, Biological; D015233:Models, Statistical; D016273:Occupational Exposure / Q000592:standards*; D012016:Reference Values
vernacular_title: Valori di riferimento ed intervalli di tolleranza.