title: Unstented and partial stented bioprostheses for aortic valve replacement--up to 6 years of follow-up.
abstract: Since January 8, 1985, three different designs of unstented (type A, n = 9) and partial stented (type B, n = 4; and type C, n = 3) glutaraldehyde preserved porcine aortic valves were used for aortic valve replacement in 16 patients with acquired aortic valve lesions. Type A and type B prostheses were implanted using a two suture row technique. In type C prostheses, only a single suture row was necessary for implantation, facilitating surgery considerably. In all patients, the fully flexible commissures of the bioprostheses were secured to the aortic wall of the recipient. There was no hospital mortality. Two patients with type A bioprostheses died due to noncardiac causes, 4 and 24 months postoperatively. One bioprosthesis in this group had to be replaced after 3 months because of insufficiency. Serial Doppler echocardiographic studies were performed up to 6 years after implantation. No significant leaflet calcification was observed. In three type A bioprostheses, a mild insufficiency without progression was recorded. The latest mean/peak transprosthetic pressure gradients were: type A: 6 +/- 4 mmHg/12 +/- 6 mmHg; type B: 6 +/- 3 mmHg/14 +/- 5 mmHg; and type C: 11 +/- 5 mmHg/18 +/- 8 mmHg. The functional results of the type A and type B bioprostheses have proven to be satisfactory. The slightly higher pressure gradients in patients with a type C bioprosthesis give rise to further refinements of its design. These results confirm the usefulness of imitating normal anatomy by using unstented or partial stented bioprostheses.
authors.affiliation: Department of Cardiovascular Surgery, University of Kiel, Federal Republic of Germany.
authors.forename: H H
authors.initials: HH
authors.lastname: Sievers
authors.forename: M
authors.initials: M
authors.lastname: Mahmoodi
authors.forename: P
authors.initials: P
authors.lastname: Marquardt
authors.forename: U
authors.initials: U
authors.lastname: Nellessen
authors.forename: M
authors.initials: M
authors.lastname: Höfig
authors.forename: W W
authors.initials: WW
authors.lastname: Angell
authors.forename: A
authors.initials: A
authors.lastname: Bernhard
mesh_terms: D000328:Adult; D000368:Aged; D001021:Aortic Valve; D001705:Bioprosthesis; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000503:physiopathology; D015607:Stents; D013536:Suture Techniques; D013997:Time Factors