title: Plasma-mediated ablation of corneal tissue at 1053 nm using a Nd:YLF oscillator/regenerative amplifier laser.
abstract: Plasma-mediated ablations were performed on human donor corneas with a short pulsed Nd:YLF laser system at 1053 nm. The pulses were 60 psec in duration at a repetition rate of 1.0 kHz. The laser beam was oriented perpendicular to the cornea surface. The threshold energy densities for ablation of epithelium, Bowman's membrane and stroma were measured. They were 6.1 +/- 1.8 J/cm2, 21.0 +/- 5.1 J/cm2 and 10.4 +/- 1.8 J/cm2, respectively. The mean rate of tissue removal at the stromal energy density threshold was about 1 micron per pulse. The walls of the laser excisions were smooth with distortions of less than 1 micron. A new quantitative model of plasma-mediated ablation is introduced and found to closely predict the observed results. Based on the promising nature of the experimental data further investigations are planned in the use of a mode locked Nd:YLF laser as an alternative to excimer lasers for refractive corneal surgery.
authors.affiliation: Department of Ophthalmology, La Jolla, University of California, San Diego 92093-0946.
authors.forename: M H
authors.initials: MH
authors.lastname: Niemz
authors.forename: E G
authors.initials: EG
authors.lastname: Klancnik
authors.forename: J F
authors.initials: JF
authors.lastname: Bille
mesh_terms: D003315:Cornea / Q000601:surgery*; D003319:Corneal Stroma / Q000601:surgery; D004735:Energy Transfer; D004867:Equipment Design; D006801:Humans; D007834:Lasers; D008028:Light Coagulation / Q000295:instrumentation / Q000379:methods*; D009354:Neodymium; D012044:Regression Analysis; D015019:Yttrium
chemical_list: D009354:Neodymium; D015019:Yttrium