[The evaluation of the possibility of using a perfluorocarbon emulsion for the normothermic perfusion of the isolated heart].
Complex study of isolated heart preparations according to some electromechanical, biochemical, gas transport, and morphofunctional criteria showed that a perfusion medium based on an emulsion of perfluorocarbons ensures an essentially better survival of a heart perfused in a recirculation regimen than with the traditionally used Krebs-Henseleite solution. The analysis shows that the use of perfluorocarbon emulsions as a perfusion medium for prolonged storage of isolated organs is promising.
Vorob'ev
S I
SI
Vasil'ev
A E
AE
Islamov
B I
BI
Kravchenko
V V
VV
D000818:Animals; D004655:Emulsions; D005466:Fluorocarbons / Q000494:pharmacology*; D006321:Heart / Q000187:drug effects*; D007552:Isotonic Solutions; D009206:Myocardium / Q000201:enzymology / Q000473:pathology; D009926:Organ Preservation / Q000379:methods; D010477:Perfusion / Q000379:methods; D011817:Rabbits; D013696:Temperature; D013997:Time Factors; D014022:Tissue Survival / Q000187:drug effects
D004655:Emulsions; D005466:Fluorocarbons; D007552:Isotonic Solutions; C051865:Krebs-Ringer solution
Otsenka vozmozhnosti ispol'zovaniia émul'sii perftoruglerodov dlia normotermicheskoĭ perfuzii izolirovannogo serdtsa.