[Comparative evaluation of the effectiveness of using peripheral vasodilators in the treatment of patients with acute myocardial infarction complicated by left-ventricular failure].
The effects of intravenous nitroglycerin, isodinit, and monizid were compared in patients with myocardial infarction complicated by left ventricular failure. Central and peripheral hemodynamic parameters, coronary venous blood flow and precardial mapping data were analyzed. The drugs were found to be potent vasodilators in the treatment of these patients; the mechanism of their action was identical. The clinical efficacy of isodinit was shown to be superior to that of monizid and nitroglycerin.
Uchaĭkina
L V
LV
Zolotareva
N Iu
NIu
Vakhliaev
V D
VD
Smirnova
I E
IE
D000328:Adult; D000368:Aged; D002311:Cardiomyopathy, Dilated / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D004341:Drug Evaluation; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D006801:Humans; D007548:Isosorbide Dinitrate / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy*; D005996:Nitroglycerin / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use*; D016277:Ventricular Function, Left / Q000187:drug effects* / Q000502:physiology
D014665:Vasodilator Agents; D005996:Nitroglycerin; D007548:Isosorbide Dinitrate
Sravnitel'naia éffektivnost' ispol'zovaniia perifericheskikh vazodilatatorov v lechenii bol'nykh ostrym infarktom miokarda oslozhnennym levozheludochkovoĭ nedostatochnost'iu.