Activation of prodrugs by antibody-enzyme conjugates.
Senter
P D
PD
Oncogen, Seattle, WA 98121.
Wallace
P M
PM
Svensson
H P
HP
Kerr
D E
DE
Hellstrom
I
I
Hellstrom
K E
KE
D000818:Animals; D000911:Antibodies, Monoclonal / Q000008:administration & dosage*; D001711:Biotransformation / Q000187:drug effects; D004337:Drug Carriers; D004798:Enzymes / Q000008:administration & dosage*; D006801:Humans; D009374:Neoplasms, Experimental / Q000188:drug therapy / Q000378:metabolism; D011355:Prodrugs / Q000493:pharmacokinetics*; D014407:Tumor Cells, Cultured / Q000187:drug effects / Q000378:metabolism
D000911:Antibodies, Monoclonal; D004337:Drug Carriers; D004798:Enzymes; D011355:Prodrugs