title: Analysis of chromosome band 1p36 alterations by chromosomal in situ suppression hybridization with a microclone DNA bank.
abstract: Alterations of the distal portion of chromosome Ip are a recurrent abnormality of several types of human cancer. In this study we show that chromosomal in situ suppression hybridization with a regional 1p36 DNA bank generated by microdissection and microcloning can be employed to detect translocations involving 1p36.
authors.affiliation: Institut für Experimentelle Pathologie, Deutsches Krebsforschungszentrum, Heidelberg, Federal Republic of Germany.
authors.forename: D
authors.initials: D
authors.lastname: Zink
authors.forename: A
authors.initials: A
authors.lastname: Weith
authors.forename: T
authors.initials: T
authors.lastname: Martinsson
authors.forename: M
authors.initials: M
authors.lastname: Schwab
mesh_terms: D002460:Cell Line; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D025063:Chromosome Disorders; D002878:Chromosomes, Human, Pair 1; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics*; D004273:DNA, Neoplasm / Q000235:genetics*; D016208:Databases, Factual; D006801:Humans; D008214:Lymphocytes; D009369:Neoplasms / Q000235:genetics*; D009447:Neuroblastoma / Q000235:genetics
chemical_list: D004273:DNA, Neoplasm; D004247:DNA