title: [Human cutaneous leishmaniasis caused by Leishmania Major MON-26 in the region of Damascus (Syria)].
abstract: In response to an epidemic of oriental sore around Damascus, an ecological and epidemiological survey was carried out in the village of Dmeir, 40 km NE of Damascus. Parasites isolated from six cases from Dmeir, and two other cases from Syria were identified as Leishmania major, zymodeme MON-26. This zymodeme is known as the agent of zoonotic cutaneous leishmaniasis from the Sub-Saharian Sahel to the Near and Middle East. This is the first report of L. major in Syria. In a group of 234 school children aged 5-11 years, the leishmanin skin test was positive in 37%, indicating a high transmission rate. The epidemic seems to be the result of agricultural and industrial development projects in the area: numbers of both the gerbil reservoir host and sandfly vector appear to be increased by the land improvement.
authors.affiliation: Hôpital Mouassat, Laboratoire Central, Université de Damas, Syrie.
authors.forename: A
authors.initials: A
authors.lastname: Khiami
authors.forename: J
authors.initials: J
authors.lastname: Dereure
authors.forename: F
authors.initials: F
authors.lastname: Pratlong
authors.forename: A
authors.initials: A
authors.lastname: Martini
authors.forename: J A
authors.initials: JA
authors.lastname: Rioux
mesh_terms: D000383:Agriculture; D000818:Animals; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D004199:Disease Vectors; D005260:Female; D005849:Gerbillinae; D006801:Humans; D007221:Industry; D007895:Leishmania tropica; D016773:Leishmaniasis, Cutaneous / Q000097:blood / Q000453:epidemiology* / Q000635:transmission; D008297:Male; D011576:Psychodidae; D016036:Seroepidemiologic Studies; D013593:Syria / Q000453:epidemiology
vernacular_title: La leishmaniose cutanée humaine à Leishmania major MON-26 aux environs de Damas (Syrie).