The effect of primaquine on the ultrastructural morphology of Pneumocystis carinii.
Ultrastructural examination of Pneumocystis grown on WI-38 human embryonic lung fibroblasts and treated with primaquine indicated progressive deterioration of cellular morphology. Thus, primaquine had a cidal effect on the organisms.
Goheen
M P
MP
Department of Pathology, Indiana University School of Medicine, Indianapolis 46202-5250.
Bartlett
M S
MS
Queener
S F
SF
Smith
J W
JW
D002478:Cells, Cultured; D006801:Humans; D011010:Pneumocystis / Q000187:drug effects* / Q000648:ultrastructure; D011319:Primaquine / Q000494:pharmacology*
D011319:Primaquine