Hereditary epidermolytic palmo-plantar keratoderma (Vörner type)--report of a family and review of the literature.
We describe a patient in whose family 13 of 26 members have a palmo-plantar keratoderma. The histopathological findings in the proband, his brother and father were those of epidermolytic hyperkeratosis. As in other families reported, this disorder was found to be inherited as an autosomal-dominant trait. A review of the literature on the clinical, genetic and associated features of this genodermatosis is presented. We also review the cutaneous conditions that may exhibit the histopathological pattern of epidermolytic hyperkeratosis.
Requena
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Departamento de Dermatología, Hospital Universitario San Carlos, Facultad de Medicina, Madrid, Spain.
Schoendorff
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Sanchez Yus
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D000328:Adult; D005260:Female; D006801:Humans; D015776:Keratoderma, Palmoplantar, Diffuse / Q000235:genetics* / Q000473:pathology; D008297:Male; D010375:Pedigree