title: Salivary testosterone concentrations in prepubertal and pubertal males: comparison with total and free plasma testosterone.
abstract: Salivary testosterone (T) levels in male children and adolescents were measured and compared with plasma T. Salivary concentrations correlated well with plasma total T (r = 0.72) and even better with free plasma T (r = 0.89) in subjects with plasma T levels of pubertal or adult levels (greater than 1.0 nmol/l). In subjects with prepubertal or low plasma T (less than 1.0 nmol/l), there was neither a correlation with plasma total, nor with free T. In hCG tests (responder and nonresponder), salivary T reflected plasma levels faithfully. The results suggest that salivary T, which is suitable for repeated sampling, is a good marker of T secretion in pubertal males.
authors.affiliation: Department of Pediatrics, University of Zurich, Kinderspital, Switzerland.
authors.forename: T
authors.initials: T
authors.lastname: Ohzeki
authors.forename: B
authors.initials: B
authors.lastname: Manella
authors.forename: C
authors.initials: C
authors.lastname: Gübelin-De Campo
authors.forename: M
authors.initials: M
authors.lastname: Zachmann
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D006801:Humans; D011627:Puberty / Q000097:blood / Q000378:metabolism*; D012463:Saliva / Q000378:metabolism*; D013739:Testosterone / Q000097:blood / Q000378:metabolism*
chemical_list: D013739:Testosterone