title: Abnormally increased iron concentration in basal ganglia in Shy-Drager syndrome. MR imaging and autonomic study.
abstract: Report of an early case of Shy-Drager syndrome in a 67 year-old woman patient. Autonomic failure was diagnosed by functional evaluation as well as laboratory tests. MR imaging disclosed a prominent putamina hypodensity in T2-weighted images at high field strength due to iron increased depositing in this basal ganglia. MR imaging evidences confirm Shy-Drager syndrome diagnosis, and contributes for differential diagnosis of idiopathic hypotension (pure autonomic failure) in special in SDS early cases.
authors.affiliation: Departamento de Neurologia, Faculdade de Ciências Médicas, Universidade Estadual de Campinas (UNICAMP), Brasil.
authors.forename: J A
authors.initials: JA
authors.lastname: Maciel Júnior
authors.forename: C M
authors.initials: CM
authors.lastname: Da Rocha
authors.forename: S
authors.initials: S
authors.lastname: Cabelho
authors.forename: M G
authors.initials: MG
authors.lastname: Pradal
mesh_terms: D000368:Aged; D001479:Basal Ganglia / Q000378:metabolism*; D001794:Blood Pressure; D005260:Female; D006339:Heart Rate; D006801:Humans; D007501:Iron / Q000378:metabolism*; D008279:Magnetic Resonance Imaging; D012791:Shy-Drager Syndrome / Q000175:diagnosis* / Q000503:physiopathology
chemical_list: D007501:Iron