Olfactory neuroblastoma--management of a rare tumour at the Queensland Radium Institute and literature review.
Olfactory neuroblastoma (esthesioneuroblastoma) is an extremely rare tumour arising from the olfactory epithelium of the nasal cavity close to the cribriform plate. Most institutions will have little experience in recognising the clinical and histological features, or management of this tumour and reliance is placed on researching the literature when the individual patient presents. This study reviews seven patients with olfactory neuroblastoma treated at the Queensland Radium Institute from 1971 to January 1990. The overall local control rate in this series is 57% (four of seven patients) and 43% of patients (three of seven) remain alive. Conservative surgery and post-operative radiotherapy is recommended for early disease and more radical surgery with post-operative radiotherapy for advanced disease.
Ahern
V A
VA
Queensland Radium Institute, Royal Brisbane Hospital.
Poulsen
M G
MG
D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000453:epidemiology* / Q000628:therapy; D009669:Nose Neoplasms / Q000453:epidemiology* / Q000628:therapy; D009831:Olfactory Mucosa; D011793:Queensland / Q000453:epidemiology