Serum sickness-like reactions from cefaclor in children.
Cefaclor is an oral semisynthetic cephalosporin that is popular in the treatment of infections in children. This drug has been associated with a serum sickness--like reaction characterized by an urticarial eruption, pruritus, arthritis, and/or arthralgias. We report 12 additional cases of cefaclor-related serum sickness--like reactions in children. All patients improved after discontinuation of the drug and no long-term complications resulted.
Hebert
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AA
Department of Dermatology, University of Texas Medical School, Houston 77030.
Sigman
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ES
Levy
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ML
D002433:Cefaclor / Q000009:adverse effects*; D002675:Child, Preschool; D003116:Color; D004890:Erythema / Q000139:chemically induced; D005260:Female; D006801:Humans; D007223:Infant; D007592:Joint Diseases / Q000139:chemically induced; D008297:Male; D012713:Serum Sickness / Q000139:chemically induced*; D012871:Skin Diseases / Q000139:chemically induced*; D014581:Urticaria / Q000139:chemically induced
D002433:Cefaclor