Contribution of vascular network transformation of the heart to the pathogenesis of ischaemic heart disease. Qualitative changes in myocardial angioarchitectonics.
Based on the idea of segmental arterial vascularization of the heart as well as qualitative assessment of angio- and microangiograms, transformations of intramyocardial vascularization induced by atherosclerotic lesions of the extramyocardial coronary arteries have been presented. Using various angiographic methods, vascularization was evaluated in 58 cases of acute and chronic ischaemic heart disease. Attention was paid to transformations of spatial structure of the vascular network and it was found that some morphological forms of ischaemic heart disease are characterized by a progressive remodelling of the peripheral vascular bed microangioarchitectonics which seems to be of major importance for exacerbation pathomechanisms. Two group of angiographic changes in the ischaemic myocardium have been distinguished, which consisted in disturbances of the segmental pattern of myocardial vascularization and disturbances of the intrasegmental structure of the arterial bundles and capillary vessels.
Zieliński
K
K
Departament of Pathomorphology, Military School of Medicine, Lódź.
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008833:Microcirculation; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology