[Burden of monogenic hereditary pathologies of the residents of Ashkhabad in the Turkmen SSR].
The results of medico-genetic investigation of population of Ashkhabad city are presented involving 229 thousand individuals (118230 Turkomans, 94050 Russians and 16720 subjects of other nationalities). Aggravation values the ethnic groups studied are as follows: Turkomen--AD (autosome-dominant = 0.86 per 1000 subjects, AR (autosome-recessive) = 2.31 per 1000 subjects, attached X chromosomes = 0.52 per 1000 males; Russians--AD = 0.93 per 1000 subjects, AR = 0.84, attached X chromosomes = 0.17 per 1000 males; other nationalities AD = 0.81, AR = 1.43, attached X chromosomes = 0.27. Aggravation of the urban Turkomen population is more valid than that of rural people. Relationship between non-accidental inbreeding rate and aggravation with autosome-recessive pathology is shown for several ethnic subdivisions of the population studied.
Turaeva
Sh M
ShM
Nekrasova
E P
EP
Kadysheva
E K
EK
Kirova
M A
MA
Orazova
G A
GA
Popova
V V
VV
D005006:Ethnicity / Q000235:genetics; D005799:Genes, Dominant; D005808:Genes, Recessive; D030342:Genetic Diseases, Inborn / Q000453:epidemiology / Q000235:genetics*; D008040:Genetic Linkage; D005828:Genetics, Population; D006801:Humans; D008297:Male; D014423:Turkmenistan; D014960:X Chromosome
Otiagoshchennost' monogennoĭ nasledstvennoĭ patologieĭ naseleniia goroda Ashkhabada Turkmenskoĭ SSR.