title: [Effect of local anesthetics on the dental pulp. Study in rats].
abstract: According to the in vitro and in vivo procedures described by Rockert and Pracros, the effect of different local anesthetics (with and without vaso-constrictive solution) have been studied on rat incisor dental pulp. Histological analysis (optical microscopy) of samples (90 rat incisors) showed: A systematic pulp response with concentrations up to 2%. This response correspond with a toxic reaction on the respiratory activity of pulp cells; A highest response with solutions containing a vaso-constrictor additive; An increasing response according to the nature of the anesthetic solution.
authors.affiliation: Institut d'Odontologie et de Stomatologie de Dakar, Senegal.
authors.forename: F
authors.initials: F
authors.lastname: Gaye
authors.forename: J P
authors.initials: JP
authors.lastname: Rocca
authors.forename: J
authors.initials: J
authors.lastname: Poulard
mesh_terms: D010129:4-Aminobenzoic Acid / Q000633:toxicity; D000779:Anesthetics, Local / Q000633:toxicity*; D000818:Animals; D003782:Dental Pulp / Q000098:blood supply / Q000187:drug effects*; D008012:Lidocaine / Q000633:toxicity; D011343:Procaine / Q000633:toxicity; D051381:Rats; D014662:Vasoconstrictor Agents / Q000633:toxicity
chemical_list: D000779:Anesthetics, Local; D014662:Vasoconstrictor Agents; D011343:Procaine; D008012:Lidocaine; D010129:4-Aminobenzoic Acid
vernacular_title: Contribution à l'étude de l'action des anesthésiques locaux sur la pulpe dentaire: expérience sur le rat.