[Toxicologic investigations of selected phenolic compounds. I. Acute and subacute toxicity of guaiacol, methyl-guaiacol and syringol].
The aim of the investigations were determination of acute (A-DL50) and subacute (C-DL50) toxicity of guaiacol, methyl-guaiacol and syringol. White Wistar male rats, body weight 250 g +/- 20, were used. From the data obtained it was concluded that tested compounds could be classified to the fourth toxicity class (Hodge-Sterner classification). Cumulation coefficients show that no cumulation of there compounds occurs in a rat organism.
Orłowski
J
J
Katedry i Zakładu Toksykologii, Akademii Medycznej im. K. Marcinkowskiego, Poznaniu. [
Boruszak
D
D
D000818:Animals; D005260:Female; D006139:Guaiacol / Q000031:analogs & derivatives* / Q000633:toxicity*; D007928:Lethal Dose 50; D008297:Male; D011748:Pyrogallol / Q000031:analogs & derivatives* / Q000633:toxicity; D051381:Rats; D017208:Rats, Wistar
D011748:Pyrogallol; C010120:pyrogallol 1,3-dimethyl ether; D006139:Guaiacol
Badania toksyczności wybranych zwiazków fenolowych. I. Toksyczność ostra i podostra gwajakolu, metylogwajakolu i syringolu.