U7 snRNP particles bind H4 pre-mRNA in vitro.
1. U7 snRNP particles were bound in vitro to H4 pre-mRNA using immunoassay experiments. 2. The processing of in vitro H4 pre-mRNAs is an SmRNP-dependent reaction. 3. U7 RNA was isolated as a unique species from the complex H4-pre-mRNA-snRNPs, which indicates its involvement in the processing of histone pre-mRNAs.
Pironcheva
G
G
Institute of Molecular Biology, Bulgarian Academy of Science, Sofia.
Russev
G
G
D004591:Electrophoresis, Polyacrylamide Gel; D006367:HeLa Cells; D006657:Histones / Q000235:genetics*; D006801:Humans; D011233:Precipitin Tests; D012322:RNA Precursors / Q000378:metabolism*; D012261:Ribonucleoproteins / Q000378:metabolism*; D017411:Ribonucleoproteins, Small Nuclear
D006657:Histones; D012322:RNA Precursors; D012261:Ribonucleoproteins; D017411:Ribonucleoproteins, Small Nuclear