[The effect of Zindep inj. preparation on levels of zinc, T-lymphocytes and beta-lysine in the blood of pregnant dairy cows].
The effects of zinc administration at a rate of 3 mg/kg lw. in the preparation Zindep inj. ad usum vet. (Biotika, Slovenská L'upca) were evaluated as exerted on zinc concentrations in the blood serum of 16 dairy cows in the middle of the 7th month of pregnancy. With respect to zinc injection, T-rosetted lymphocytes and beta-lysine activity were inestigated. Blood was collected from all dairy cows from v. jugularis before the preparation was administered, on days 2, 5, 8, 15, 30 and 60 after Zindep administration. Atom absorption spectrophotometry, applying a flame technique on a Perkin Elmer 1100 apparatus (Bíres, 1986), was used to determine Zn concentrations in the blood serum of all dairy cows. T-lymphocytes were determined by a rosette test after Paul et al. (1977), and beta-lysine was detected spectrophotometrically after Bucharin et al. (1987). Zinc dynamics in the blood serum of dairy cows is presented in Fig. 1. The starting values of zinc in the test cows were 9.68 +/- 2.30 mumol/l and in the control ones 10.15 +/- 1.27 mumol/l. Zincaemia of experimental dairy cows was significantly lower (P less than 0.01) on day 2 after Zindep administration, in comparison with the control group. A significant increase in zinc concentrations in the blood serum of experimental animals, in comparison with the control ones, was observed from day 8 to day 60 (P less than 0.01). The maximum zincaemia values were recorded in experimental dairy cows within days 15 and 30 (15.65 +/- 3.33, and/or 14.55 +/- 2.10 mumol/l).(ABSTRACT TRUNCATED AT 250 WORDS)
Bíres
J
J
Vysoká skola veterinárska, Kosice.
Harvan
M
M
Hudák
P
P
Mucha
L
L
Juhásová
Z
Z
D000818:Animals; D002417:Cattle / Q000097:blood*; D003612:Dairying; D005260:Female; D007958:Leukocyte Count; D008239:Lysine / Q000031:analogs & derivatives* / Q000097:blood; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000097:blood*; D013601:T-Lymphocytes; D015032:Zinc / Q000494:pharmacology*
C076854:Zindep; C065591:beta-lysine; D015032:Zinc; D008239:Lysine
Vplyv prípravku Zindep inj. na zinkémiu, T-lymfocyty a beta-lyzín u gravidných dojníc.