title: [Bile lake: a complication of transcatheter hepatic arterial infusion and embolization therapy (TAI, TAE)].
abstract: A 74-year-old man with hepatocellular carcinoma developed cholangitis and bile lake in the liver after repeated TAI (anticancer drug-lipiodol suspension) and gelfoam TAE. Despite percutaneous transhepatic drainage, he died of hepatic failure 34 months after the first TAI and TAE. We speculate that cholangitis and bile lake were caused by chemical toxicity of highly concentrated anticancer drug to the bile duct and compression of the proximal bile duct by the tumor.
authors.affiliation: Department of Radiology, Nagasaki University School of Medicine.
authors.forename: K
authors.initials: K
authors.lastname: Ashizawa
authors.forename: N
authors.initials: N
authors.lastname: Matsunaga
authors.forename: N
authors.initials: N
authors.lastname: Asoh
authors.forename: M
authors.initials: M
authors.lastname: Morikawa
authors.forename: I
authors.initials: I
authors.lastname: Isomoto
authors.forename: A
authors.initials: A
authors.lastname: Ajimu
authors.forename: T
authors.initials: T
authors.lastname: Fukuda
authors.forename: J
authors.initials: J
authors.lastname: Irie
authors.forename: K
authors.initials: K
authors.lastname: Hayashi
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D001646:Bile; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy / Q000628:therapy*; D002761:Cholangitis / Q000209:etiology; D004621:Embolization, Therapeutic / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy / Q000628:therapy*
chemical_list: D000970:Antineoplastic Agents