Effects of liver disease on red blood cell acetaldehyde in alcoholics and non-alcoholics.
High endogenous levels of acetaldehyde were found in the blood (mainly in red blood cells) of patients with liver disease of various etiologies. The presence of severe liver injury increased the blood acetaldehyde response to ethanol consumption and resulted in a more prolonged persistence of high levels after ethanol withdrawal.
Uppal
R
R
Alcohol Research and Treatment Center, Mount Sinai School of Medicine, Bronx, NY.
Rosman
A
A
Hernández
R
R
Baraona
E
E
Lieber
C S
CS
D000079:Acetaldehyde / Q000097:blood*; D000428:Alcohol Drinking / Q000097:blood; D004912:Erythrocytes / Q000378:metabolism*; D005234:Fatty Liver / Q000097:blood; D006801:Humans; D008103:Liver Cirrhosis / Q000097:blood; D008104:Liver Cirrhosis, Alcoholic / Q000097:blood*; D008107:Liver Diseases / Q000097:blood*; D012016:Reference Values
D000079:Acetaldehyde