title: Infectious disease of the spine. Diagnostic and treatment considerations.
abstract: Excellence in treating spinal infections demands recognition of the fact that all spine infections are potential disasters. One needs to possess a complete knowledge of the pathology and pathogenesis of these disorders. An aggressive diagnostic approach is required. Surgery may be required for diagnosis, abscess drainage, neurologic involvement, deformity, or refractoriness to conservative therapy. Selection of the proper operation, as well as its skillful execution, are prerequisites. These goals, along with the appropriate use of antibiotics, and, most importantly, vigilance for the presence of spinal infection, will allow us to avoid the high rates of morbidity and mortality experienced by others in the past.
authors.affiliation: Department of Orthopaedic Surgery, University of Pennsylvania School of Medicine, Philadelphia.
authors.forename: R J
authors.initials: RJ
authors.lastname: Wisneski
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001706:Biopsy; D002985:Clinical Protocols; D003646:Debridement; D003663:Decision Trees; D004322:Drainage; D006801:Humans; D007239:Infections / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D013122:Spinal Diseases / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy
chemical_list: D000900:Anti-Bacterial Agents