title: Adequate function of the immune system and physiological microflora are closely correlated.
abstract: It is already known that physiological microflora of the digestive system plays an important role in local immunity. Studies on immunomodulating activity of some autoantibodies have shown that drugs affecting intestinal microflora possess potent immunosuppressive effect on systemic immunity. These observations inspired to recent investigation on the mechanisms of the influence of digestive tract bacteria on the immune system.
authors.affiliation: Institut für Medizinische Mikrobiologie und Hygiene, Universität zu Köln, FRG.
authors.forename: G
authors.initials: G
authors.lastname: Pulverer
authors.forename: J
authors.initials: J
authors.lastname: Beuth
authors.forename: H L
authors.initials: HL
authors.lastname: Ko
authors.forename: W
authors.initials: W
authors.lastname: Roszkowski
authors.forename: K
authors.initials: K
authors.lastname: Roszkowski
mesh_terms: D000818:Animals; D001420:Bacteria, Aerobic / Q000187:drug effects* / Q000276:immunology; D001421:Bacteria, Anaerobic / Q000187:drug effects* / Q000276:immunology; D001424:Bacterial Infections / Q000150:complications / Q000188:drug therapy / Q000276:immunology / Q000382:microbiology*; D004064:Digestive System / Q000187:drug effects / Q000276:immunology / Q000382:microbiology*; D004195:Disease Models, Animal; D005759:Gastroenteritis / Q000150:complications / Q000188:drug therapy / Q000276:immunology / Q000382:microbiology*; D005770:Gastrointestinal Neoplasms / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D007108:Immune Tolerance / Q000187:drug effects* / Q000276:immunology; D008802:Mezlocillin / Q000009:adverse effects* / Q000627:therapeutic use; D051379:Mice; D008807:Mice, Inbred BALB C; D012513:Sarcoma, Experimental / Q000209:etiology* / Q000276:immunology / Q000473:pathology
chemical_list: D008802:Mezlocillin