The regularity of intersteroidal relations in urine as related to the law of mass action.
The relation between 14 urinary steroid excretions was investigated by intersteroidal regression analysis with urine from 59 follicular stage women, 135 luteal stage women and 5 female patients with adrenal disorders. The regularity of intersteroidal relation in urine, as detected for all steroid pairs of all groups studied, was explained in terms of the law of mass action, and a chemical equilibrium point was located with a high degree of reproducibility for each steroid and for each group. The theoretical and practical usefulness of urinary steroid regression analysis is emphasized in relation to the possible impact of multihormonal information on endocrinology.
Kodama
M
M
Kodama Research Institute of Preventive Medicine, Nagoya, Japan.
Kodama
T
T
Totani
R
R
Aso
Y
Y
D000307:Adrenal Gland Diseases / Q000652:urine*; D000738:Androsterone / Q000031:analogs & derivatives / Q000652:urine; D003480:Cushing Syndrome / Q000652:urine; D003687:Dehydroepiandrosterone / Q000652:urine; D005260:Female; D005498:Follicular Phase / Q000502:physiology; D006801:Humans; D007700:Kinetics; D008433:Mathematics; D008593:Menopause; D008597:Menstrual Cycle / Q000652:urine*; D008954:Models, Biological; D012016:Reference Values; D012044:Regression Analysis; D013256:Steroids / Q000652:urine*
D013256:Steroids; C015961:11-ketoandrosterone; D003687:Dehydroepiandrosterone; D000738:Androsterone