title: [Diagnosis of the causes and prevention of intrauterine fetal death in the second trimester of pregnancy in women with hyperandrogenism].
abstract: Differential diagnosis of the causes of intrauterine fetal death was carried out in 84 women; in 57 of them it was due to hyperandrogenism of various origins. 63.2% of patients suffered from mixed (combined ++ovario-adrenal) androgen hypersecretion, 33.3% from the adrenal and only 3.5% of women from the ovarian form of hyperandrogenism. Relationship between the frequency of intrauterine fetal death, the pregnancy term and the form of hyperandrogenism was revealed. Differential diagnosis of hyperandrogenism forms and preparatory pathogenetic therapy helped preserve the pregnancy and resulted in delivery of a viable healthy child in 77.4% of the examined women.
authors.forename: V M
authors.initials: VM
authors.lastname: Sidel'nikova
authors.forename: V G
authors.initials: VG
authors.lastname: Orlova
authors.forename: A T
authors.initials: AT
authors.lastname: Raisova
authors.forename: A A
authors.initials: AA
authors.lastname: Agadzhanova
mesh_terms: D000302:Adrenal Cortex / Q000187:drug effects / Q000378:metabolism*; D000308:Adrenocortical Hyperfunction / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D000328:Adult; D003687:Dehydroepiandrosterone / Q000037:antagonists & inhibitors / Q000378:metabolism*; D005260:Female; D005313:Fetal Death / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D010053:Ovary / Q000187:drug effects / Q000378:metabolism*; D011239:Prednisolone / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D011262:Pregnancy Trimester, Second; D013739:Testosterone / Q000037:antagonists & inhibitors / Q000378:metabolism*
chemical_list: D013739:Testosterone; D003687:Dehydroepiandrosterone; D011239:Prednisolone
vernacular_title: Diagnostika prichin i profilaktika vnutriutrobnoĭ gibeli ploda vo II trimestre beremennosti u zhenshchin s giperandrogenieĭ.