title: Decrease in erythrocyte survival in Theileria sergenti-infected calves determined by non-radioactive chromium labelling method.
abstract: Pathogenesis of anemia in the calves infected with Theileria sergenti was investigated from the viewpoint of erythrocyte survival decrease in the circulating blood. For investigation of erythrocyte survival a method of erythrocyte labelling with non-radioactive chromium (50Cr) was utilized. It was found that (1) the erythrocyte survival decreased markedly in the T. sergenti-infected calves compared with that in the uninfected calves; the survival rate of 25.7% for infected calves and 86.0% for uninfected ones on the fourth day after re-introduction of the labelled erythrocytes into the original donors, and that (2) the survival of non-parasitized erythrocytes in the infected calves was also decreased, which indicates no obvious relationship between parasitism and decrease in survival of erythrocytes.
authors.affiliation: Systematic Diagnosis Research Division, National Institute of Animal Health, Ibaraki, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Yagi
authors.forename: N
authors.initials: N
authors.lastname: Ito
authors.forename: I
authors.initials: I
authors.lastname: Kunugiyama
mesh_terms: D000740:Anemia / Q000209:etiology / Q000662:veterinary*; D000818:Animals; D002417:Cattle; D004905:Erythrocyte Aging; D004912:Erythrocytes / Q000502:physiology*; D013801:Theileriasis / Q000097:blood* / Q000150:complications