Repeated 99mTc-Sestamibi studies for the evaluation of salvaged myocardium and of its relationship with postinfarction ischemia.
Pre- and post-treatment myocardial scans with 99mTc-Sestamibi demonstrated effective reperfusion after thrombolysis in a patient with acute myocardial infarction. Late follow-up images showed at rest a further noteworthy reduction of the uptake defect and that during exercise a large part of the salvaged territory became ischemic. This report demonstrates that a remarkable amount of myocardium in the posttreatment images was hibernated; furthermore, it was possible to visualize directly that the salvaged territory is the actual site of exercise induced postinfarction ischemia.
Sciagrà
R
R
Department of Cardiology, Careggi Hospital, Florence, Italy.
Bisi
G
G
Santoro
G M
GM
Leoncini
M
M
Fazzini
P F
PF
Meldolesi
U
U
D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000188:drug therapy; D015428:Myocardial Reperfusion Injury / Q000000981:diagnostic imaging*; D015609:Organotechnetium Compounds; D017256:Technetium Tc 99m Sestamibi; D015912:Thrombolytic Therapy; D013997:Time Factors; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D015899:Tomography, Emission-Computed, Single-Photon
D015609:Organotechnetium Compounds; D017256:Technetium Tc 99m Sestamibi; D010959:Tissue Plasminogen Activator