title: [Side effects of oral contraceptives in the first treatment cycle].
abstract: In order to compare the secondary effects of oral contraceptive pills during the first cycle of application, 308 women between the age of 25 and 45 were interrogated by questionnaires about their subjective complaints. The patients received a contraceptive within an In-vitro-Fertilization-program (IVF-program) in preparation for a stimulation treatment to follow. The study consisted of two parts: at the beginning a pilot study was carried out in which retrospectively a pill containing 0.150 mg Desogestrel and 0.030 mg Ethinylestradiol and a contraceptive containing 0.075 mg Gestoden and 0.030 mg Ethinylestradiol were compared. In a following prospective randomized examination a product, new on the market, containing 0.250 mg Norgestimat and 0.035 mg Ethinylestradiol, was included. The most common secondary effects, occurring in 34% of our patients, were spottings and break through bleedings. Regarding the secondary effects--during the first cycle of application--no significant difference between the contraceptives could be established.
authors.affiliation: Institut für Sterilitätsbetreuung, II. Universitäts-Frauenklinik, Wien.
authors.forename: W
authors.initials: W
authors.lastname: Feichtinger
authors.forename: P
authors.initials: P
authors.lastname: Babor
authors.forename: K M
authors.initials: KM
authors.lastname: Herczeg
authors.forename: M
authors.initials: M
authors.lastname: Heyda
authors.forename: R
authors.initials: R
authors.lastname: Hoffmann
authors.forename: B
authors.initials: B
authors.lastname: Plöckinger
authors.forename: B
authors.initials: B
authors.lastname: Steinhauser
mesh_terms: D000328:Adult; D003277:Contraceptives, Oral, Combined / Q000008:administration & dosage / Q000009:adverse effects*; D017135:Desogestrel; D004305:Dose-Response Relationship, Drug; D004997:Ethinyl Estradiol / Q000008:administration & dosage / Q000009:adverse effects; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D009644:Norgestrel / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives; D009652:Norpregnenes / Q000008:administration & dosage / Q000009:adverse effects; D010865:Pilot Projects; D011446:Prospective Studies; D012189:Retrospective Studies
chemical_list: D003277:Contraceptives, Oral, Combined; D009652:Norpregnenes; C033273:Gestodene; D009644:Norgestrel; D004997:Ethinyl Estradiol; D017135:Desogestrel; C017576:norgestimate
vernacular_title: Nebenwirkungen oraler Kontrazeptiva im ersten Einnahmezyklus.