title: Primary squamous cell carcinoma of the caecum.
abstract: A case of primary squamous cell carcinoma of the caecum arising in a tubulo-villous adenoma is described. This rare lesion develops following genomic derangement of the multipotential colonic stem cells. The literature is reviewed and factors contributing towards squamous cell differentiation discussed.
authors.affiliation: Department of Surgery, Derriford Hospital, Plymouth, UK.
authors.forename: M G
authors.initials: MG
authors.lastname: Wyatt
authors.forename: T J
authors.initials: TJ
authors.lastname: Clarke
authors.forename: C
authors.initials: C
authors.lastname: Teasdale
mesh_terms: D000236:Adenoma / Q000473:pathology*; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002430:Cecal Neoplasms / Q000473:pathology*; D002471:Cell Transformation, Neoplastic; D006801:Humans; D008297:Male; D012307:Risk Factors