Erythroderma, palmoplantar keratoderma and profound failure to thrive in an infant.
The case is reported of a female infant, who at the age of 3 months developed severe erythroderma, marked hyperkeratosis of the palms and soles and subsequently extreme growth failure and intermittent diarrhoea. Her course was complicated by life-threatening infections but detailed investigation revealed no recognized underlying metabolic or immune abnormality.
Judge
M R
MR
Department of Dermatology, Hospitals for Sick Children, London, U.K.
Shield
J P
JP
Cant
A
A
Strobel
S
S
Levin
M
M
Reiser
J
J
Harper
J I
JI
D003873:Dermatitis, Exfoliative / Q000150:complications / Q000473:pathology*; D005183:Failure to Thrive / Q000150:complications / Q000473:pathology*; D005260:Female; D006225:Hand / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D015776:Keratoderma, Palmoplantar, Diffuse / Q000150:complications / Q000473:pathology*; D011379:Prognosis; D012867:Skin / Q000473:pathology; D013577:Syndrome