[Results of selected cytochemical studies of mature granulocytes in myelodysplastic syndromes and various other hematologic diseases].
The activity of alkaline phosphatase and peroxidase was measured in polymorphonuclears in 20 cases of myelodysplasia syndromes, 10 cases of chronic myeloid leukaemia. Reduced phosphatase activity was found in 5 cases and peroxidase activity in 3 cases of myelodysplasia syndromes. No evident correlation was noted between the activity of these enzymes and prognosis. Increased proportion of peroxidase-negative granulocytes was observed, moreover, in most cases of chronic myeloid leukaemia. The observations will be continued in larger material.
Mariańska
B
B
Klinika Hematologiczna Instytutu Hematologii, Warszawa.
Apel
D
D
Maj
S
S
D000469:Alkaline Phosphatase / Q000097:blood*; D006098:Granulocytes / Q000201:enzymology*; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000097:blood*; D015470:Leukemia, Myeloid, Acute / Q000097:blood*; D009190:Myelodysplastic Syndromes / Q000097:blood*; D010544:Peroxidases / Q000097:blood*; D011087:Polycythemia Vera / Q000097:blood*; D055728:Primary Myelofibrosis / Q000097:blood*
D010544:Peroxidases; D000469:Alkaline Phosphatase
Wyniki wybranych badań cytochemicznych dojrzałych granulocytów w przebiegu zespołów mielodysplastycznych i niektórych innych chorób układu krwiotwórczego.