title: Variations and coding features of the sequence spanning the replication terminus of Bacillus subtilis 168 and W23 chromosomes.
abstract: In a comparative study of the sequences of the 3-kb regions of DNA spanning the replication terminus, terC, of Bacillus subtilis strains 168 and W23, it was found that the latter contained an insertion of a large open reading frame (ORF405) whose translated protein product is a member of the cytochrome P-450 family. The insertion was about 34 nucleotides upstream from a putative promoter for the rtp gene. The sequenced regions contained a number of other ORFs. The translation product of one (ORF238) is a member of a previously identified oxidoreductase superfamily. The translation product of another (ORF257) is significantly similar to the proC product of Escherichia coli, but this ORF does not code for a functional proC product of B. subtilis.
authors.affiliation: Department of Biochemistry, University of Sydney, NSW, Australia.
authors.forename: K S
authors.initials: KS
authors.lastname: Ahn
authors.forename: R G
authors.initials: RG
authors.lastname: Wake
mesh_terms: D000595:Amino Acid Sequence; D001412:Bacillus subtilis / Q000235:genetics*; D001483:Base Sequence; D002876:Chromosomes, Bacterial; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics / Q000378:metabolism; D004261:DNA Replication / Q000235:genetics*; D004251:DNA Transposable Elements; D004269:DNA, Bacterial / Q000235:genetics*; D005091:Exons; D014644:Genetic Variation; D008969:Molecular Sequence Data; D005810:Multigene Family; D016366:Open Reading Frames; D011401:Promoter Regions, Genetic; D011762:Pyrroline Carboxylate Reductases / Q000235:genetics; D012091:Repetitive Sequences, Nucleic Acid; D012689:Sequence Homology, Nucleic Acid
chemical_list: D004251:DNA Transposable Elements; D004269:DNA, Bacterial; D003577:Cytochrome P-450 Enzyme System; D011762:Pyrroline Carboxylate Reductases