[The presence of antibodies against glycoprotein I (gI) of the virus of Aujeszky's disease in colostrum and milk of sows].
The possibility of using sow's milk to detect antibodies to the gI protein of Aujeszky's virus was studied by the present authors. Antibody titres in serum (collected less than 30 days ante partum) and colostrum from sixty-three sows were determined using a commercially available ELISA; twenty-four of thirty-seven animals vaccinated with gI-positive vaccines showed an antibody response in both colostrum and serum. The titre in colostrum was significantly higher than it was in serum. Antibodies could not be detected in serum or in colostrum of the twenty-six animals which were only vaccinated with gI-negative vaccines. Subsequently, anti-gI titres were determined in milk collected during lactation. Antibodies were also detectable in milk of animals showing high colostrum titres (greater than 128) for at least seventeen days. This period decreased as the initial colostrum titre became lower. Antibodies could still be detected in milk of animals vaccinated with gI-positive vaccine, which were sero-negative at the time of the experiment. Milk therefore seems to be a useful alternative to serum in detecting anti-gI antibodies in sows.
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Gezondheidsdienst voor Dieren in Noord-Nederland, Drachten.
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D000818:Animals; D000914:Antibodies, Viral / Q000302:isolation & purification*; D003126:Colostrum / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005260:Female; D011558:Herpesvirus 1, Suid / Q000276:immunology; D008892:Milk / Q000276:immunology*; D013552:Swine / Q000276:immunology*; D014759:Viral Envelope Proteins / Q000276:immunology*; D014765:Viral Vaccines / Q000276:immunology
D000914:Antibodies, Viral; D014759:Viral Envelope Proteins; D014765:Viral Vaccines; C042966:pseudorabies virus glycoproteins
De aanwezigheid van antistoffen tegen glycoproteïne I (gI) van het virus van de ziekte van Aujeszky in biest en melk van zeugen.