title: Inhibitory action of extracts of Maclura aurantiaca and Epilobium hirsutum on tumour models in mice.
abstract: Primary screening of alcohol extracts of fruits of Maclura aurantiaca (Moraceae) and the overground part of Epilobium hirsutum (Onagraceae) was conducted in order to test the anti-tumour action on models in mice. Applied in doses of 100 mg/kg and 90 mg/kg, Maclura extract increased the life span of the mice by 158 and 152% accordingly in leucosis P-388 and ascitic tumour of Ehrich. In doses of 1 mg/kg and 3 mg/kg the Epilobium extract prolonged the life span of the mice by 156 and 158% accordingly in leucosis P-388 and ascitic tumour of Ehrlich.
authors.affiliation: National Centre of Oncology, Medical Academy, Sofia, Bulgaria.
authors.forename: E
authors.initials: E
authors.lastname: Voynova
authors.forename: S
authors.initials: S
authors.lastname: Dimitrova
authors.forename: E
authors.initials: E
authors.lastname: Naydenova
authors.forename: P
authors.initials: P
authors.lastname: Karadjov
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy*; D005260:Female; D007941:Leukemia P388 / Q000188:drug therapy*; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts