Rosacea-like lesions due to familial Mycobacterium avium-intracellulare infection.
Mycobacterium avium-intracellulare (MAI) is a non-tuberculous, nonlepromatous or "atypical" mycobacterium now seen frequently in patients with acquired immunodeficiency syndrome (AIDS). In the past decade, the incidence appears to have increased in non-AIDS patients. Although cutaneous involvement is rare, two brothers without detectable immune defects who both presented with cutaneous MAI infection are described; the older brother also has disseminated disease. The cutaneous presentation of MAI, as well as immune and genetic defects that may predispose to mycobacterial infection, are discussed.
Nedorost
S T
ST
Department of Dermatology, Cleveland Clinic Foundation, Ohio.
Elewski
B
B
Tomford
J W
JW
Camisa
C
C
D000328:Adult; D003937:Diagnosis, Differential; D005148:Facial Dermatoses / Q000175:diagnosis / Q000235:genetics*; D005192:Family Health; D006801:Humans; D008297:Male; D015270:Mycobacterium avium-intracellulare Infection / Q000175:diagnosis / Q000235:genetics*; D012393:Rosacea / Q000175:diagnosis*; D012874:Skin Diseases, Infectious / Q000175:diagnosis / Q000235:genetics*