title: [An elderly case of small cell lung cancer showing a good partial response by chronic daily administration of oral etoposide].
abstract: An 86-year-old man was admitted to our hospital with complaints of dyspnea and productive cough, and diagnosed as small cell lung cancer with sputum cytology. We concluded that he was unsuitable for standard aggressive intravenous chemotherapy because of an old age, a poor performance status and cardiac complication. He was treated with oral etoposide (100 mg/day x 16.5 days), and showed a good partial response and improvement of clinical symptoms. Toxicities were leukopenia, alopecia, and anorexia. Daily oral administration of etoposide is considered to be effective and useful for elderly patient with small cell lung cancer.
authors.affiliation: Nakamura Shimin Hospital, Kouchi, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Ishikawa
authors.forename: E
authors.initials: E
authors.lastname: Shimizu
authors.forename: K
authors.initials: K
authors.lastname: Kawaji
authors.forename: J
authors.initials: J
authors.lastname: Mukai
authors.forename: K
authors.initials: K
authors.lastname: Tani
authors.forename: A
authors.initials: A
authors.lastname: Okubo
authors.forename: T
authors.initials: T
authors.lastname: Ogura
authors.forename: T
authors.initials: T
authors.lastname: Sano
authors.forename: T
authors.initials: T
authors.lastname: Yamashita
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000369:Aged, 80 and over; D018288:Carcinoma, Small Cell / Q000188:drug therapy*; D004334:Drug Administration Schedule; D005047:Etoposide / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy*; D008297:Male; D012074:Remission Induction; D013997:Time Factors
chemical_list: D005047:Etoposide