title: The effectiveness of tipi in the treatment of hip and knee osteoarthritis--a preliminary report.
abstract: Osteoarthritis (OA) is a common painful inflammatory condition occurring mainly in the later half of life. Hip and knee are the joints mostly affected. Petiveria alliacea (tipi) popularly known as an anti-rheumatic medicine, has been used by OA patients to relief pain. This one-week cross-over double-blind trial has preliminary evaluated the analgesic effect of tipi tea in 14 patients with hip and knee OA. Imperata exaltata (sape) was used as the Placebo tea. The pain assessments that were made at baseline and before the start of the second treatment period by treatment groups were comparable. While taking tipi or placebo tea patients experienced a statistically significant improvement in pain on motion and pain at night. The comparison between the improvements reported while on tipi and placebo tea, however, did not disclose any statistically significant difference. At the conclusion of the study 7 patients preferred tipi tea and 6 preferred placebo tea (NS). Two patients reported insomnia, one during placebo treatment and the other during tipi treatment.
authors.affiliation: Escola Paulista de Medicina, São Paulo, Brasil.
authors.forename: M B
authors.initials: MB
authors.lastname: Ferraz
authors.forename: R B
authors.initials: RB
authors.lastname: Pereira
authors.forename: L E
authors.initials: LE
authors.lastname: Coelho Andrade
authors.forename: E
authors.initials: E
authors.lastname: Atra
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000700:Analgesics / Q000627:therapeutic use*; D001628:Beverages; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007719:Knee Joint; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000150:complications / Q000188:drug therapy*; D015207:Osteoarthritis, Hip / Q000188:drug therapy; D010146:Pain / Q000188:drug therapy / Q000209:etiology; D010147:Pain Measurement
chemical_list: D000700:Analgesics