Can buspirone induce rebound, dependence or abuse?
Buspirone is a newer anxiolytic which differs chemically and pharmacologically from the benzodiazepines. The question as to whether buspirone can induce rebound, dependence, or abuse can be examined through a variety of clinical and control studies, as well as animal studies, together with meticulous follow-up of adverse reports. It is concluded that, on present evidence, the short-term use of buspirone is unlikely to be followed by rebound or long-term use through dependence; nor is abuse likely to be a problem.
Lader
M
M
Institute of Psychiatry, De Crespigny Park, London.
D001008:Anxiety Disorders / Q000188:drug therapy* / Q000523:psychology; D002065:Buspirone / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D012307:Risk Factors; D019966:Substance-Related Disorders / Q000209:etiology*
D002065:Buspirone