Condensation reactions between 2-phenylthio-2,3-dideoxyribose derivatives and nucleic bases.
The effects of phenylthio group at C-2 of 2,3-dideoxyribose were examined for the stereoselectivities in condensation reactions between sugars and pyrimidine bases. In the case of mono-PhS sugar, the 1,2-trans-anomers were mainly obtained in the ratio of 9:1. Condensation reactions with di-PhS-sugar gave the anomeric mixtures of alpha:beta = 2:8.
Kawakami
H
H
Life Science Research Laboratory, Japan Tobacco Inc., Kanagawa.
Ebata
T
T
Koseki
K
K
Matsumoto
K
K
Matsushita
H
H
D002241:Carbohydrates / Q000737:chemistry; D003855:Deoxyribose / Q000737:chemistry*; D015394:Molecular Structure; D011743:Pyrimidines / Q000737:chemistry
D002241:Carbohydrates; D011743:Pyrimidines; D003855:Deoxyribose