title: Nd:YAG laser with sapphire tip combined with balloon angioplasty in peripheral arterial occlusions. Long-term results.
abstract: In 167 patients with complete occlusion (greater than 3 cm) of the femoropopliteal artery, percutaneous transluminal laser angioplasty (PTLA) was performed after an unsuccessful attempt at crossing with a guide wire and was immediately followed by balloon dilatation. An Nd-YAG laser and an optical fiber delivery system with a sapphire tip serving as a contact probe were used for PTLA. In 132 of 167 (79%) patients, the occluded segment was successfully reopened. Clinical symptoms improved in 126 of 167 (75%) patients. PTLA was unsuccessful in 35 patients, and in 15 of these, injury of the vessel wall occurred. In one patient, surgical drainage of a large hematoma became necessary. All patients in whom recanalization had been achieved were randomized to receive long-term treatment with either phenprocumarol or acetylsalicylic acid (ASA) plus dipyridamole to prevent rethrombosis. At 36 months of follow-up, the cumulative patency rate (CPR) was 63%. A complete reobstruction in 32 patients (24%) and a partial reobstruction in 15 patients (11%) were found angiographically. The CPR after 36 months was significantly lower (p less than 0.05) in patients younger than 60 years of age (54%) than in patients older than 60 (68%); it was also significantly lower (p less than 0.05) in patients with reduced peripheral runoff (55%) due to obstructed arteries of the lower leg than in patients with unaffected runoff (73%). The CPR was 65% in recanalized segments shorter than 7 cm and was 62% in recanalized segments longer than 7 cm.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Internal Medicine, Karl Franzens University School of Medicine, Graz, Austria.
authors.forename: E
authors.initials: E
authors.lastname: Pilger
authors.forename: J
authors.initials: J
authors.lastname: Lammer
authors.forename: H
authors.initials: H
authors.lastname: Bertuch
authors.forename: G
authors.initials: G
authors.lastname: Stark
authors.forename: M
authors.initials: M
authors.lastname: Decrinis
authors.forename: K P
authors.initials: KP
authors.lastname: Pfeiffer
authors.forename: G J
authors.initials: GJ
authors.lastname: Krejs
mesh_terms: D000368:Aged; D000800:Angioplasty, Balloon; D016342:Angioplasty, Laser; D001157:Arterial Occlusive Diseases / Q000628:therapy*; D001241:Aspirin / Q000627:therapeutic use; D004176:Dipyridamole / Q000627:therapeutic use; D005260:Female; D005263:Femoral Artery; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010644:Phenprocoumon / Q000627:therapeutic use; D011150:Popliteal Artery; D012008:Recurrence; D013997:Time Factors
chemical_list: D004176:Dipyridamole; D010644:Phenprocoumon; D001241:Aspirin