title: [A new milk formula: iron bioavailability and effect on prevention of iron deficiency in infants].
abstract: Iron bioavailability from a modified cow milk, formula (LPM) (which included additional iron as 5 mg/l ferrous sulfate and ascorbic acid, 50 mg/l) was examined in 11 adult women using the extrinsic radioactive tag method. The geometric mean absorption from LPM was 13% (reference dose absorption = 26%). The effect of this formula on iron nutrition of infants was studied in 43 healthy term infants weaned spontaneously before 3 months of age which were given LPM until 9 months of age. Another 45 infants (controls) were fed full fat, non fortified powdered cow's milk (LP) as delivered through the National Complementary Food Program (PNAC-Chile) and additional 45 infants were given fortified a cow's milk formula (LF) with ferrous sulfate (iron: 15 mg/l and ascorbic acid: 100 mg/l). Solid foods (vegetables and meat) were introduced to all these babies from age 4 months. At 9 months of age 4% infants fed LPM had evidence of anemia vs. 2% and 20% of infants given LF and LP formulae respectively. This results suggests that LPM is effective in preventing iron deficiency anemia in infants.
authors.affiliation: INTA, Instituto de Nutrición y Tecnología de los Alimentos, Universidad de Chile.
authors.forename: E
authors.initials: E
authors.lastname: Hertrampf
authors.forename: F
authors.initials: F
authors.lastname: Pizarro
authors.forename: A
authors.initials: A
authors.lastname: Pereyra
authors.forename: V
authors.initials: V
authors.lastname: Vega
mesh_terms: D000328:Adult; D000747:Anemia, Hypochromic / Q000517:prevention & control; D000818:Animals; D001682:Biological Availability; D005260:Female; D005526:Food, Formulated; D005527:Food, Fortified; D006801:Humans; D007223:Infant; D007225:Infant Food; D007501:Iron / Q000097:blood / Q000493:pharmacokinetics*; D000090463:Iron Deficiencies; D008137:Longitudinal Studies; D008875:Middle Aged; D008892:Milk / Q000378:metabolism*
chemical_list: D007501:Iron
vernacular_title: Nueva fórmula láctea: biodisponibilidad del hierro y efecto en la prevención de su deficiencia en lactantes.