title: Isolation method for lysine-excreting mutants of Arthrobacter globiformis.
abstract: To improve the yield of lysine by the isolate, auxotrophic mutants were isolated. Among the mutants, only one auxotrophic mutant required vitamin B12. This mutant produced alpha-alanine. About 200 mutants resistant to the lysine analog S-(2-aminoethyl)-L-cysteine were isolated and some of them produced well above the wild type.
authors.affiliation: Department of Botany, School of Life Science, Visva-Bharati University, West Bengal, India.
authors.forename: S K
authors.initials: SK
authors.lastname: Sen
mesh_terms: D000409:Alanine / Q000096:biosynthesis; D001173:Arthrobacter / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D001431:Bacteriological Techniques; D003545:Cysteine / Q000031:analogs & derivatives / Q000494:pharmacology; D004352:Drug Resistance, Microbial / Q000235:genetics; D008239:Lysine / Q000096:biosynthesis*; D008769:Methylnitronitrosoguanidine; D009154:Mutation
chemical_list: D008769:Methylnitronitrosoguanidine; C000204:S-2-aminoethyl cysteine; D008239:Lysine; D003545:Cysteine; D000409:Alanine