title: [Mycotoxins as a risk factor for the origin of diseases and production decreases in swine facilities--an epidemiologic study].
abstract: Feed samples checked for the mycotoxins zearalenone and ochratoxin A from the harvest 1987 were positive at a markedly higher percentage (37.5%) compared to previous years, which is explained by the especially unfavourable harvesting conditions of 1987. In certain herd problems affecting the digestive or respiratory tract, mycotoxins could be detected with a much higher frequency (64.7% and 50.0% respectively). The mean level detected in feed samples by thin layer chromatography ranged within 30.3 ppb for zearalenone and within 58.3 ppb for ochratoxin A. In most cases there was a history of infertility. Considering the clinical situation, which is presented comparatively in herds with positive mycotoxin results, the possible involvement of mycotoxins in the disease, even at very low concentrations, is pointed out. In this context, zearalenone is incriminated of being an indicator of a multitoxic process besides its own direct effects. According to own experiences low levels of zearalenone in the range of 20-50 ppb in the feed have to be considered hazardous. If changing of pig feed in cases of herd problems will be recommended, a level of less than 10 ppb of zearalenone, especially in sow and piglet rations, should not be exceeded. Same may be valid to ochratoxin A.
authors.affiliation: Tierärztlichen Ambulanz Schwarzenbek, Fachbereich Veterinärmedizin der Freien Universität Berlin.
authors.forename: C
authors.initials: C
authors.lastname: Ewald
authors.forename: A
authors.initials: A
authors.lastname: Rehm
authors.forename: C
authors.initials: C
authors.lastname: Haupt
mesh_terms: D000821:Animal Feed / Q000506:poisoning*; D000818:Animals; D002855:Chromatography, Thin Layer; D005506:Food Contamination; D009793:Ochratoxins / Q000506:poisoning*; D013552:Swine; D013553:Swine Diseases / Q000209:etiology*; D015025:Zearalenone / Q000506:poisoning*
chemical_list: D009793:Ochratoxins; C025589:ochratoxin A; D015025:Zearalenone
vernacular_title: Mykotoxine als Risikofaktor für das Entstehen von Krankheiten und Leistungsminderung in Schweinebeständen--eine epidemiologische Studie.