title: [Gadolinium-DTPA as an oral contrast medium for magnetic resonance tomography of the pancreas].
abstract: 52 patients with normal pancreas, pancreatitis and pancreatic tumors were examined by magnetic resonance imaging (Magnetom 0.5 T). Using T1-, proton density- and T2-weighted spin-echo sequences images were obtained before and after oral administration of Gadolinium-DTPA (Gd-DTPA, 1 mM, 15 g/l Mannit, 5-13 ml/kg). Gd-DTPA resulted in hyperintense labeling of small bowel in all sequences and improved visualization of pancreatic head, body and tail in 15, 14 and 7 of 27 patients with normal pancreas and in 17, 8 and 6 of 25 patients with diseased pancreas. Better delineation of pseudocysts and tumorous gut wall invasion were diagnostically profitable. With regard to motion artifact reduced MRI of the intestine using fast sequences Gd-DTPA may be a suitable oral contrast agent to improve the imaging of the pancreas.
authors.affiliation: Radiologische Klinik und Poliklinik, Universitätsklinikum Rudolf Virchow, Standort Charlottenburg, Freie Universität Berlin.
authors.forename: K
authors.initials: K
authors.lastname: Neumann
authors.forename: S
authors.initials: S
authors.lastname: Kaminsky
authors.forename: M
authors.initials: M
authors.lastname: Gogoll
authors.forename: W
authors.initials: W
authors.lastname: Clauss
authors.forename: M
authors.initials: M
authors.lastname: Langer
authors.forename: R
authors.initials: R
authors.lastname: Felix
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media / Q000008:administration & dosage*; D005260:Female; D005682:Gadolinium / Q000008:administration & dosage; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds / Q000008:administration & dosage; D010190:Pancreatic Neoplasms / Q000175:diagnosis*; D010195:Pancreatitis / Q000175:diagnosis*; D004369:Pentetic Acid / Q000008:administration & dosage
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA
vernacular_title: Gadolinium-DTPA als orales Kontrastmittel für die magnetische Resonanztomographie des Pankreas.