title: Systemic contact dermatitis from pseudoephedrine.
abstract: A patient with rhinitis developed systemic contact dermatitis when starting oral treatment with Rhinalair, containing pseudoephedrine hydrochloride. A few months later, another oral treatment Rinutan, containing norephedrine hydrochloride, provoked a more severe generalized eczema. Patch test reactions were strongly positive to ephedrine and pseudoephedrine, slightly positive to phenylephrine and negative to epinephrine. Norephedrine was not tested.
authors.affiliation: Clinique Dermatologique, Hôpital Civil, Strasbourg, France.
authors.forename: R R
authors.initials: RR
authors.lastname: Tomb
authors.forename: J P
authors.initials: JP
authors.lastname: Lepoittevin
authors.forename: F
authors.initials: F
authors.lastname: Espinassouze
authors.forename: E
authors.initials: E
authors.lastname: Heid
authors.forename: J
authors.initials: J
authors.lastname: Foussereau
mesh_terms: D000368:Aged; D003877:Dermatitis, Contact / Q000209:etiology*; D003875:Drug Eruptions / Q000209:etiology*; D004809:Ephedrine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D010665:Phenylpropanolamine / Q000009:adverse effects; D012008:Recurrence; D012220:Rhinitis / Q000188:drug therapy
chemical_list: D010665:Phenylpropanolamine; D004809:Ephedrine