title: A kit formulation for preparation of iodine-123-IBZM: a new CNS D-2 dopamine receptor imaging agent.
abstract: A method for the preparation of iodine-123IBZM, a central nervous system D-2 imaging agent, is reported. By using a rapid filtration technique to remove the unreacted iodide, the preparation can be completed in less than 20 min (overall yield greater than 60%). The product, with high purity (greater than or equal to 95%) and specific activity, is suitable for human use.
authors.affiliation: Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104.
authors.forename: M P
authors.initials: MP
authors.lastname: Kung
authors.forename: B L
authors.initials: BL
authors.lastname: Liu
authors.forename: Y Y
authors.initials: YY
authors.lastname: Yang
authors.forename: J J
authors.initials: JJ
authors.lastname: Billings
authors.forename: H F
authors.initials: HF
authors.lastname: Kung
mesh_terms: D000818:Animals; D001549:Benzamides; D001921:Brain / Q000000981:diagnostic imaging*; D008297:Male; D011759:Pyrrolidines; D011877:Radionuclide Imaging; D051381:Rats; D011919:Rats, Inbred Strains; D011933:Reagent Kits, Diagnostic; D011954:Receptors, Dopamine; D017448:Receptors, Dopamine D2
chemical_list: D001549:Benzamides; D011759:Pyrrolidines; D011933:Reagent Kits, Diagnostic; D011954:Receptors, Dopamine; D017448:Receptors, Dopamine D2; C055743:3-iodo-2-hydroxy-6-methoxy-N-((1-ethyl-2-pyrrolidinyl)methyl)benzamide