Parallel stranded DNA under scanning tunnelling microscope: the main characteristics of the double helix.
Using the scanning tunnelling microscopy we have directly observed the parallel stranded DNA of 43 bp in length, containing alternating AT-stretches. The double helix is right-handed and has the same width of each grooves equal to 17.4 A. The average pitch of the helical turn is about 34 A. The parallel double helix possesses no more than 8.6 bases per one turn. The diameter of the parallel stranded DNA molecule is 17-18 A. We conclude that in parallel DNA double helix the angle between N-glycoside bounds in trans-Crick-Watson base pairs is close to 180 degrees.
Tchurikov
N A
NA
Institute of Molecular Biology, USSR Academy of Sciences, Moscow.
Zhu
J D
JD
Li
M Q
MQ
Chernov
B K
BK
D001482:Base Composition; D001483:Base Sequence; D004247:DNA / Q000737:chemistry / Q000648:ultrastructure*; D016252:Microscopy, Scanning Tunneling / Q000379:methods; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation
D004247:DNA