title: Molecular cloning of human plasma glutathione peroxidase gene and its expression in the kidney.
abstract: A genomic clone containing the human plasma glutathione peroxidase (GSH-Px) gene has been isolated using a rat plasma GSH-Px cDNA as a probe. The partial nucleotide sequence of the clone completely matched the sequence of the human plasma GSH-Px cDNA. The results of Southern blot hybridization indicate that the human plasma GSH-Px gene consists of at least 4 exons and 3 introns, and spans about 12 kb. RNA blot analysis demonstrated that the human plasma GSH-Px gene is expressed in the kidney.
authors.affiliation: Department of Cell Biology, Tokai University School of Medicine, Kanagawa, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Yoshimura
authors.forename: H
authors.initials: H
authors.lastname: Suemizu
authors.forename: Y
authors.initials: Y
authors.lastname: Taniguchi
authors.forename: K
authors.initials: K
authors.lastname: Watanabe
authors.forename: Y
authors.initials: Y
authors.lastname: Nomoto
authors.forename: Y
authors.initials: Y
authors.lastname: Katsuoka
authors.forename: S
authors.initials: S
authors.lastname: Arimori
authors.forename: T
authors.initials: T
authors.lastname: Moriuchi
mesh_terms: D000818:Animals; D003001:Cloning, Molecular; D005979:Glutathione Peroxidase / Q000096:biosynthesis / Q000097:blood / Q000235:genetics*; D006801:Humans; D007668:Kidney / Q000201:enzymology*; D009928:Organ Specificity / Q000235:genetics; D051381:Rats; D015183:Restriction Mapping
chemical_list: D005979:Glutathione Peroxidase