title: Diffuse Lewy body disease presenting with a supranuclear gaze palsy.
abstract: A patient with diffuse Lewy body disease presented with supranuclear vertical and horizontal ophthalmoplegia, dementia, axial rigidity and falls, bradykinesia and pyramidal signs. This broadens the clinical presentation of this pathological diagnosis and re-emphasises the heterogeneity of patients diagnosed clinically as progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome).
authors.affiliation: National Hospital for Nervous Diseases, Queen Square, London, UK.
authors.forename: J M
authors.initials: JM
authors.lastname: Fearnley
authors.forename: T
authors.initials: T
authors.lastname: Revesz
authors.forename: D J
authors.initials: DJ
authors.lastname: Brooks
authors.forename: R S
authors.initials: RS
authors.lastname: Frackowiak
authors.forename: A J
authors.initials: AJ
authors.lastname: Lees
mesh_terms: D000368:Aged; D002540:Cerebral Cortex / Q000473:pathology*; D003704:Dementia / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure*; D008297:Male; D009454:Neurofibrils / Q000648:ultrastructure; D009474:Neurons / Q000473:pathology; D009483:Neuropsychological Tests; D009886:Ophthalmoplegia / Q000175:diagnosis* / Q000473:pathology; D010300:Parkinson Disease / Q000175:diagnosis* / Q000473:pathology; D013494:Supranuclear Palsy, Progressive / Q000175:diagnosis* / Q000523:psychology