title: Ketoconazole-induced fulminant hepatitis necessitating liver transplantation.
abstract: The most serious side effect of ketoconazole is hepatitis, which has proved fatal in seven reported cases. We present a case of fulminant hepatic failure in a 45-year-old Oriental woman that probably would have been fatal except for a successful liver transplant. A review of the literature of fatalities associated with ketoconazole is presented.
authors.affiliation: Department of Medicine, John A. Burns School of Medicine, Honolulu, Hawaii.
authors.forename: T E
authors.initials: TE
authors.lastname: Knight
authors.forename: C Y
authors.initials: CY
authors.lastname: Shikuma
authors.forename: J
authors.initials: J
authors.lastname: Knight
mesh_terms: D002177:Candidiasis / Q000188:drug therapy; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000601:surgery; D005260:Female; D006801:Humans; D007654:Ketoconazole / Q000009:adverse effects*; D016031:Liver Transplantation; D008875:Middle Aged; D014009:Onychomycosis / Q000188:drug therapy
chemical_list: D007654:Ketoconazole