Successful treatment of focal hepatic candidiasis in a patient with acute myeloid leukaemia.
A 38-year-old woman with acute myeloid leukaemia developed focal hepatic candidiasis. Ultrasonography and computerised tomography revealed the hepatic lesion and definite diagnosis was established by percutaneous liver biopsy. The use of a cumulative dose of 6.6 g of amphotericin B in combination with 5-fluorocytosine resulted in successful eradication of the fungus. The difficulties in making an antemortem diagnosis are well recognised and optimal therapy of the condition remains to be defined.
Tsui
E
E
Department of Medicine, Queen Mary Hospital, University of Hong Kong.
Liang
R
R
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use*; D002177:Candidiasis / Q000175:diagnosis / Q000188:drug therapy*; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D005437:Flucytosine / Q000627:therapeutic use*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008107:Liver Diseases / Q000175:diagnosis / Q000188:drug therapy*; D012074:Remission Induction; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
D000666:Amphotericin B; D005437:Flucytosine