[From a statistical standpoint].
Issues in the statistical evaluation for therapeutic efficacy of surgical adjuvant modality therapy on the patients suffering from gastrointestinal cancers were mentioned as follows: 1) When a therapeutic effect is evaluated, it is important that a well-controlled, randomized trial should be requested under the statistical consideration. 2) On a series of systematized process such as protocol planning, coordination and administration, analysis and its interpretation, such a trial should be enough to complete several conditions which are mutually understood and coordinated between doctors and statisticians, and which are rich in knowledge and skill for the trial in each institutions. 3) Method of overview and its application for clinical data has been mentioned as an method of exploratory trials.
Nakazato
H
H
Department of Gastroenterological Surgery, Aichi Cancer Center Hospital, Nagoya, Japan.
Sakamoto
J
J
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002985:Clinical Protocols; D002986:Clinical Trials as Topic / Q000706:statistics & numerical data*; D006801:Humans; D015201:Meta-Analysis as Topic; D011379:Prognosis; D013274:Stomach Neoplasms / Q000188:drug therapy / Q000401:mortality
D000970:Antineoplastic Agents