[Structure of the antineoplastic antibiotic variamycin].
The results of the structural study of antitumor antibiotic variamycin and its peracetyl derivative by 1H-and 13C-NMR spectroscopy are reported. Structures of carbohydrate chains of the antibiotics molecule are revised. Variamycin is shown to be 2-[beta-cymmarosyl(1-3)-beta-oliosyl (1-3)-beta-olivosyl]-6-[beta-olivosyl (1-3)-beta-olivosyl] chromomycinone.
Shashkov
A S
AS
Iashunskiĭ
D V
DV
Zhdanovich
Iu V
IuV
Lokshin
G B
GB
D000903:Antibiotics, Antineoplastic / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002247:Carbon Isotopes; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D008926:Plicamycin / Q000031:analogs & derivatives* / Q000737:chemistry
D000903:Antibiotics, Antineoplastic; D002247:Carbon Isotopes; C009950:variamycin; D002244:Carbon; D008926:Plicamycin
Stroenie protivoopukholevogo antibiotika variamitsina.