title: Response of laying hens to supplemental niacin.
abstract: Two experiments were conducted to investigate the effect of supplemental niacin on laying hen performance and liver fat and egg cholesterol content. In Experiment 1, 16 replicate groups of four adjacently caged birds were fed corn and soybean meal diets calculated to contain 22, 44, 66, or 132 mg supplemental niacin/kg (23.2, 38.7, 57.0, and 143 mg/kg niacin by analysis). Egg production, egg weight, feed intake, and eggshell quality were assessed each 28 days through a 364-day trial period. After 280 days, cholesterol content on three eggs per replicate was measured. At the end of the study, one bird per replicate was killed for subjective scoring of liver fat content. In Experiment 2, 24 birds from the control treatment (22 mg/kg supplemental niacin) of Experiment 1 were retained and fed for a subsequent 28-day period. Over this time, eight birds were each fed diets containing 22, 522, or 1,022 mg/kg supplemental niacin. Egg cholesterol content was measured in eggs collected on the last 3 days of the study. In Experiment 1, birds fed 66 or 132 mg/kg supplemental niacin/kg produced more eggs (P less than .05) than birds fed 22mg/kg. Niacin supplementation affected shell quality (P less than .05). Dietary niacin level had no effect on egg cholesterol content of liver lipid evaluation. In Experiment 2, supplementary niacin levels up to 1,022 mg/kg, which more closely stimulates therapeutic levels used for humans, again failed to affect egg cholesterol content.
authors.affiliation: Department of Animal and Poultry Science, University of Guelph, Ontario, Canada.
authors.forename: S
authors.initials: S
authors.lastname: Leeson
authors.forename: L J
authors.initials: LJ
authors.lastname: Caston
authors.forename: J D
authors.initials: JD
authors.lastname: Summers
mesh_terms: D000821:Animal Feed; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D002645:Chickens / Q000254:growth & development* / Q000378:metabolism / Q000502:physiology; D002784:Cholesterol / Q000032:analysis; D004435:Eating / Q000187:drug effects; D004531:Eggs / Q000032:analysis / Q000592:standards; D005260:Female; D008055:Lipids / Q000032:analysis; D008099:Liver / Q000737:chemistry; D009525:Niacin / Q000008:administration & dosage / Q000494:pharmacology*; D010058:Oviposition / Q000187:drug effects*
chemical_list: D008055:Lipids; D009525:Niacin; D002784:Cholesterol