title: Prognostic value of preoperative tests in the surgical treatment of ascites with the implant of Le Veen shunts in cirrhotics.
abstract: In the period of January 1978 to October 1988, 32 Le Veen shunts (LVS) were implanted in 20 patients, out of which 16 were alcoholic cirrhotics and 4 postnecrotic cirrhotics. In the present study, we correlated preoperative laboratory data of these patients with their postoperative evolution, comparing the clinical results of patients who survived more than 30 days (13 patients = 65%) with the results of those who died within the same period (7 patients = 35%). For that matter, 14 laboratory tests were performed in order to measure the serum levels of hematocrit, hemoglobin, urea, creatinine, sodium, potassium, bilirubin, albumin, AST, ALT, alkaline phosphatase, fibrinogen, gamma GT and prothrombin activity. After statistical analysis, we observed that 6 of the 14 tests performed could be considered of prognostic value in the following decreasing order of importance: fibrinogen, alkaline phosphatase, prothrombin activity, urea, gamma GT and bilirubin. We observed that all the 7 patients who died prematurely presented 3 or more of these levels altered, when compared with standard values. Based on these data, we concluded that serum levels of fibrinogen, alkaline phosphatase, urea, gamma GT, bilirubin and activity of prothrombin proved to be important factors in determining the prognosis of immediate survival in cirrhotic patients who underwent LVS implantation. We also concluded that when 3 or more of these factors are altered, the implant of LVS is contraindicated, whatever clinical criteria for indication and contraindication were taken into account.
authors.affiliation: Department of Gastroenterology, University of São Paulo Medical School, Brazil.
authors.forename: L A
authors.initials: LA
authors.lastname: D'Albuquerque
authors.forename: A
authors.initials: A
authors.lastname: de Oliveira e Silva
authors.forename: T
authors.initials: T
authors.lastname: Genzini
authors.forename: M P
authors.initials: MP
authors.lastname: de Miranda
authors.forename: F
authors.initials: F
authors.lastname: Roldan-Molina
mesh_terms: D000328:Adult; D000368:Aged; D001201:Ascites / Q000097:blood / Q000401:mortality / Q000601:surgery*; D002423:Cause of Death; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010536:Peritoneovenous Shunt / Q000401:mortality; D011183:Postoperative Complications / Q000401:mortality; D011300:Preoperative Care; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate