title: [Use of pefloxacin in boutonneuse fever].
abstract: On the basis of previous studies, the authors tested pefloxacin, a new generation quinolone, for the treatment of Mediterranean spotted fever. Treatment with this drug brought about complete recovery with rapid subsidence of clinical symptoms and normalization of instrumental and laboratory parameters. This antibiotic should therefore be listed as one of the agents suitable for combatting rickettsial infections and its use should be encouraged in view of its easy handling, excellent compliance and the possibility for oral administration.
authors.affiliation: Divisione di Medicina Generale, Ospedale Civile Polispecializzato, Anzio.
authors.forename: G
authors.initials: G
authors.lastname: Di Lascio
authors.forename: S
authors.initials: S
authors.lastname: Salvini
authors.forename: S
authors.initials: S
authors.lastname: Cermola
authors.forename: C
authors.initials: C
authors.lastname: Grasso
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001907:Boutonneuse Fever / Q000175:diagnosis / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015366:Pefloxacin / Q000627:therapeutic use*
chemical_list: D015366:Pefloxacin
vernacular_title: Sull'impiego della pefloxacina nella febbre bottonosa.