[Synthesis of baogongteng A analogs].
In order to search for antiglaucoma drugs, three analogs (5, 12 and 10) of Baogongteng A were synthesized. The analog 12 shows myotic and reducing intraocular pressure activities in rabbit.
Yang
J H
JH
Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing.
Xie
X J
XJ
D000818:Animals; D001643:Bridged Bicyclo Compounds / Q000138:chemical synthesis*; D019086:Bridged Bicyclo Compounds, Heterocyclic; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D008916:Miotics / Q000138:chemical synthesis*; D011817:Rabbits; D014326:Tropanes
D001643:Bridged Bicyclo Compounds; D019086:Bridged Bicyclo Compounds, Heterocyclic; D004365:Drugs, Chinese Herbal; D008916:Miotics; D014326:Tropanes; C027863:bao gong teng A