title: Microangiopathy of the brain, retina, and ear: improvement without immunosuppressive therapy.
abstract: We describe a pregnant young woman with branch retinal arteriolar occlusions, encephalopathy, and hearing loss in whom we demonstrated a patent foramen ovale. She improved while receiving anticoagulants and no immunosuppressive therapy. The microangiopathic syndrome of retinopathy, encephalopathy, and deafness may be due to a disturbance of coagulation and/or microembolism.
authors.affiliation: Department of Neurology, University of Iowa College of Medicine, Iowa City 52242.
authors.forename: D L
authors.initials: DL
authors.lastname: Gordon
authors.forename: S S
authors.initials: SS
authors.lastname: Hayreh
authors.forename: H P
authors.initials: HP
authors.lastname: Adams
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D002561:Cerebrovascular Disorders / Q000188:drug therapy / Q000503:physiopathology*; D004423:Ear / Q000098:blood supply*; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D008833:Microcirculation; D011247:Pregnancy; D012164:Retinal Diseases / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology; D012171:Retinal Vessels / Q000473:pathology / Q000503:physiopathology*; D013577:Syndrome; D014652:Vascular Diseases / Q000188:drug therapy / Q000503:physiopathology*
chemical_list: D000925:Anticoagulants