title: Dehydroepiandrosterone sulfate, cholesterol, hemoglobin, and anthropometric measures related to growth in male adolescents.
abstract: Sixty-four white boys between 10.6 and 14.3 years old participated in an adolescent nutrition assessment study evaluating dehydroepiandrosterone sulfate (DHEAS) as a measure of maturation. DHEAS, an adrenal androgen, is low in childhood and rises with the development of secondary sexual characteristics. Biochemical measures included plasma DHEAS assessed by radioimmunoassay, cholesterol assessed by an enzymatic method, and hemoglobin assessed by the cyanmethemoglobin method. Midarm muscle area (MAMA) was calculated from midarm circumference and triceps fatfold measurements. DHEAS was correlated significantly with height, weight, MAMA, and hemoglobin. By age, significant differences were found for height, weight, and MAMA, but not for any of the biochemical measures. For boys with DHEAS concentration less than 3 mumol/L, values for height, weight, body mass index, MAMA, and hemoglobin were significantly different from those for boys with higher DHEAS concentrations. No significant differences were found for age or nutrient intakes by DHEAS concentration groups. Mean plasma cholesterol concentrations decreased with increases in age and with maturation evidenced by higher DHEAS concentration. Cholesterol concentration was negatively correlated with height and MAMA. Mean nutrient intakes estimated by a quantitative food frequency questionnaire met or exceeded the Recommended Dietary Allowances for these age groups. DHEAS identified maturation differences in male adolescents.
authors.affiliation: Department of Food, Nutrition and Institution Administration, Oklahoma State University, Stillwater 74078.
authors.forename: A B
authors.initials: AB
authors.lastname: Arquitt
authors.forename: B J
authors.initials: BJ
authors.lastname: Stoecker
authors.forename: J S
authors.initials: JS
authors.lastname: Hermann
authors.forename: E A
authors.initials: EA
authors.lastname: Winterfeldt
mesh_terms: D000293:Adolescent / Q000502:physiology*; D000886:Anthropometry; D001827:Body Height; D015992:Body Mass Index; D001835:Body Weight; D002648:Child; D002784:Cholesterol / Q000097:blood*; D003687:Dehydroepiandrosterone / Q000031:analogs & derivatives* / Q000097:blood; D019314:Dehydroepiandrosterone Sulfate; D006128:Growth; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D008297:Male; D009752:Nutritional Status; D012741:Sexual Maturation
chemical_list: D006454:Hemoglobins; D003687:Dehydroepiandrosterone; D019314:Dehydroepiandrosterone Sulfate; D002784:Cholesterol