title: Linkage relationship between incontinentia pigmenti (IP2) and nine terminal X long arm markers.
abstract: Linkage data for familial incontinentia pigmenti (IP2) and nine X chromosomal markers are reported. Previously found linkage between IP2 and the DXS52 locus is confirmed with the maximum lod score of 6.19 at a recombination fraction of 0.03. Linkage is also established with loci DXS134, DXS15 and DXS33. Multipoint analysis allows us to localize the IP2 locus outside a block of seven linked markers of the Xq28 region.
authors.affiliation: Unité INSERM U. 12, Hôpital des Enfants-Malades, Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Sefiani
authors.forename: R
authors.initials: R
authors.lastname: M'rad
authors.forename: L
authors.initials: L
authors.lastname: Simard
authors.forename: A
authors.initials: A
authors.lastname: Vincent
authors.forename: C
authors.initials: C
authors.lastname: Julier
authors.forename: L
authors.initials: L
authors.lastname: Holvoet-Vermaut
authors.forename: S
authors.initials: S
authors.lastname: Heuertz
authors.forename: N
authors.initials: N
authors.lastname: Dahl
authors.forename: J F
authors.initials: JF
authors.lastname: Stalder
authors.forename: M O
authors.initials: MO
authors.lastname: Peter
mesh_terms: D002874:Chromosome Mapping; D004262:DNA Restriction Enzymes; D005260:Female; D005804:Genes, Lethal; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D007184:Incontinentia Pigmenti / Q000235:genetics*; D008297:Male; D010375:Pedigree; D014960:X Chromosome
chemical_list: D005819:Genetic Markers; D004262:DNA Restriction Enzymes