[Photodynamic therapy for genitourinary carcinomas--report of 26 tumors in 17 patients].
Twenty-six genito-urinary carcinomas in 17 patients were treated with photodynamic therapy (PDT). The complete response rate was 88.5%, significant response rate 7.7% and mild response rate 3.8%. Three tumors recurred (including 1 cancer in situ) during 9-23 months follow-up. Ultrastructurally, it was found that the necrosis of the malignant cells developed gradually and mitochondria was the major target of injury. No deleterious side effect was found.
Huang
J G
JG
First Hospital, Dalian Medical College.
D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy; D002295:Carcinoma, Transitional Cell / Q000188:drug therapy*; D005260:Female; D005834:Genital Neoplasms, Male / Q000188:drug therapy; D017324:Hematoporphyrin Derivative; D006414:Hematoporphyrin Photoradiation; D006415:Hematoporphyrins / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy*
D000970:Antineoplastic Agents; D006415:Hematoporphyrins; D017324:Hematoporphyrin Derivative