title: [Duration of second remission of Hodgkin's disease in children. Results of treatment achieved by the Polish Leukemia and Malignant Lymphoma Therapy in Children Group].
abstract: Recurrence was noted in 18.5% of 194 children, in which chemotherapy with MVPP regimen produced complete I remission. In 6 out of 36 children with recurrent disease MVPP regimen was repeated, while the remaining children were treated with B-DOPA alone or combined with MOPP regimen. Local radiotherapy was used in 17 children. The second complete remission was achieved in 30 (83.7%) children. Thirteen out of 36 patients died because of the progress of the disease (11 children), and for complications (2 children). Percentage of persisting 5- and 10-year II remissions are 58.2% and 54.6%, respectively. A 5- and 10-year survival rates in children with recurrent disease are 80.5% and 60.5%, respectively. Our relatively favourable results we associate--first of all--with the chemotherapy intensity.
authors.affiliation: Kliniki Hematologii Dzieciecej Instytutu Pediatrii AM w Krakowie.
authors.forename: W
authors.initials: W
authors.lastname: Balwierz
authors.forename: J
authors.initials: J
authors.lastname: Armata
authors.forename: A
authors.initials: A
authors.lastname: Moryl-Bujakowska
authors.forename: T
authors.initials: T
authors.lastname: Depowska
authors.forename: U
authors.initials: U
authors.lastname: Radwańska
authors.forename: M
authors.initials: M
authors.lastname: Kaczmarek
authors.forename: M
authors.initials: M
authors.lastname: Ochocka
authors.forename: E
authors.initials: E
authors.lastname: Stańczak
authors.forename: D
authors.initials: D
authors.lastname: Sońta-Jakimczyk
authors.forename: J
authors.initials: J
authors.lastname: Bogusławska-Jaworska
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002648:Child; D003131:Combined Modality Therapy; D004295:Dihydroxyphenylalanine / Q000008:administration & dosage; D005260:Female; D006689:Hodgkin Disease / Q000401:mortality / Q000628:therapy*; D006801:Humans; D008297:Male; D008466:Mechlorethamine / Q000008:administration & dosage; D011239:Prednisolone / Q000008:administration & dosage; D011241:Prednisone / Q000008:administration & dosage; D011344:Procarbazine / Q000008:administration & dosage; D012074:Remission Induction; D015996:Survival Rate; D014747:Vinblastine / Q000008:administration & dosage; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D011344:Procarbazine; D008466:Mechlorethamine; D014750:Vincristine; D014747:Vinblastine; D004295:Dihydroxyphenylalanine; D011239:Prednisolone; D011241:Prednisone
vernacular_title: Trwałość drugiej remisji w chorobie Hodgkina u dzieci. Wyniki leczenia Polskiej Grupy ds. Leczenia Białaczki i Chłoniaków Złośliwych u Dzieci.