Linear IgA disease with haemorrhagic pompholyx and dapsone-induced neutropenia.
A case of haemorrhagic pompholyx occurring in a 29-year-old man with linear IgA disease is described. There were several features in our patient that are usually seen in chronic bullous disease of childhood. Treatment with dapsone cleared the eruption but induced a progressive yet reversible neutropenia.
Duhra
P
P
South Warwickshire Hospital, Warwick, U.K.
Charles-Holmes
R
R
D000328:Adult; D003622:Dapsone / Q000009:adverse effects; D011146:Eczema, Dyshidrotic / Q000188:drug therapy*; D006470:Hemorrhage / Q000188:drug therapy*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D008297:Male; D009503:Neutropenia / Q000139:chemically induced*; D012872:Skin Diseases, Vesiculobullous / Q000150:complications*
D007070:Immunoglobulin A; D003622:Dapsone