Progress toward the synthesis of nonionic oligonucleotide analogues with sulfonate and sulfonamide internucleotide linkages.
The synthesis of building blocks for the preparation of nonionic oligonucleotide analogues with sulfonate and sulfonamide internucleotide linkages is described. Coupling conditions for the conversion of several of these monomers to dimers are also described.
Secrist
J A
JA
Organic Chemistry Department, Southern Research Institute, Birmingham, AL 35255-5305.
Crooks
P A
PA
Maddry
J A
JA
Reynolds
R C
RC
Rathore
A S
AS
Ahktar
M S
MS
Montgomery
J A
JA
D015226:Dinucleoside Phosphates / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D015394:Molecular Structure; D009841:Oligonucleotides / Q000138:chemical synthesis*; D013449:Sulfonamides; D013451:Sulfonic Acids; D013873:Thionucleotides
D015226:Dinucleoside Phosphates; D007202:Indicators and Reagents; D009841:Oligonucleotides; D013449:Sulfonamides; D013451:Sulfonic Acids; D013873:Thionucleotides