Acute non-A, non-B hepatitis in a hospital population in Warsaw, Poland: clinical and epidemiological aspects.
In the years 1986-1988, 530 consecutive cases of acute viral hepatitis were admitted to an infectious disease hospital in Warsaw. Hepatitis A was diagnosed in 34 cases (6.4%), hepatitis B in 436 (82.3%), CMV infection in five (0.9%), and 55 cases (10.4%) were classified as hepatitis non-A, non-B. In 47 cases (85%) of non-A, non-B hepatitis, there was evidence of parenteral transmission, whereas in eight (15%), the source of infection was unknown. Chronic liver disease developed in 50% of patients with parenteral exposure, but there were no cases with known exposure. Seroconversion to anti-HCV was observed only in patients with parenteral exposure, and 60% of followed up cases developed antibodies within 6 months.
Laskus
T
T
Department of Immunopathology, Institute of Infectious and Parasitic Diseases, Medical Academy, Warsaw, Poland.
Lupa
E
E
Cianciara
J
J
Slusarczyk
J
J
D000208:Acute Disease; D000328:Adult; D000368:Aged; D003428:Cross Infection / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission; D003937:Diagnosis, Differential; D016174:Hepacivirus / Q000276:immunology; D006506:Hepatitis A / Q000175:diagnosis / Q000453:epidemiology; D006508:Hepatitis Antibodies / Q000097:blood; D006509:Hepatitis B / Q000175:diagnosis / Q000453:epidemiology; D006526:Hepatitis C / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission; D006801:Humans; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D011446:Prospective Studies; D065227:Transfusion Reaction
D006508:Hepatitis Antibodies