title: [Effect of continuous barbiturate treatment on the blood flow of the mean cerebral artery in severe brain injured patients. A transcranial Doppler study].
abstract: Blood flow velocity (BFV) of the MCA has been studied by TCD of 15 patients with non operated serious cranial trauma, treated with continuous barbiturate therapy. Without hemodynamic and ventilatory modifications (PaCO2), average BFV were lowered during the course of treatment and were raised significantly when it was stopped. This study poses the question of the indication and the methods of barbiturate treatment during serious cranial trauma.
authors.affiliation: Département d'anesthésie-réanimation chirurgicale, Centre hospitalier régional et universitaire, Angers.
authors.forename: N
authors.initials: N
authors.lastname: Boishardy
authors.forename: J C
authors.initials: JC
authors.lastname: Granry
authors.forename: J P
authors.initials: JP
authors.lastname: Jacob
authors.forename: L
authors.initials: L
authors.lastname: Lepoittevin
authors.forename: M
authors.initials: M
authors.lastname: Cavellat
mesh_terms: D000328:Adult; D001783:Blood Flow Velocity; D001930:Brain Injuries / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D004453:Echoencephalography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D013874:Thiopental / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D013874:Thiopental
vernacular_title: Effet du traitement barbiturique continu sur le flux sanguin de l'artère cérébrale moyenne des traumatisés crâniens graves. Etude par Doppler transcrânien.