title: [Malignant fibrous histiocytoma of soft tissue: description of 10 cases].
abstract: We analyze the clinical and histological features of 10 cases of malignant fibrous histiocytoma of soft tissue. Nine belonged to the pleomorphic-verticillate variety and one was myxoid. The initial clinical feature was a palpable mass in all cases except three with retroperitoneal localization, where constitutional symptoms predominated. After therapy (surgery in all, associated with radiotherapy in four), seven patients had local relapse and two had distant metastases. 50% died, with a mean survival of 13 months. We discuss the prognostic factors and the therapeutic approach, with emphasis on aggressive therapy and the need for radical surgery and postoperative adjuvant therapy.
authors.affiliation: Departamento de Medicina Interna, Hospital Miguel Servet, Zaragoza.
authors.forename: J
authors.initials: J
authors.lastname: Povar
authors.forename: J M
authors.initials: JM
authors.lastname: Franco
authors.forename: J R
authors.initials: JR
authors.lastname: Muñoz
authors.forename: C
authors.initials: C
authors.lastname: Horndler
authors.forename: P
authors.initials: P
authors.lastname: Arazo
authors.forename: A
authors.initials: A
authors.lastname: Portoles
authors.forename: J
authors.initials: J
authors.lastname: Velilla
authors.forename: A
authors.initials: A
authors.lastname: Gutiérrez
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy
vernacular_title: Histiocitoma fibroso maligno de partes blandas: descripción de 10 casos.