title: Hypercarbia is not the determinant factor of systemic arterial hypertension during carboperitoneum in laparoscopy.
abstract: Laparoscopy performed with carboperitoneum in 30 women of infertility was studied to evaluate the changes of systemic blood pressure and end-tidal carbon dioxide (CO2) and their relationship. The patients were randomly divided into 2 groups. In group I (n = 15), the patient's respiration was set to maintain a nearly constant end-tidal CO2 by adjusting the minute ventilation. In group II (n = 15), the minute ventilation was kept constant to monitor the changes of end-tidal CO2. Perioperative measurements included end-tidal CO2, systolic blood pressure (SBP), diastolic blood pressure (DBP), and heart rate (HR) which were recorded the moment just before intra-abdominal CO2 administration and every 2 min thereafter for at least 10 min. The data showed that in both groups there were time-related changes of blood pressure with a maximum increase about 20-30% of baseline level found at 6 min later after the beginning of intra-peritoneal CO2 insufflation, and no significant change of HR was noted. The intergroup comparisons of SBP, DBP and HR were not statistically significant. With regard to end-tidal CO2 change in group II, it also appeared in a time-related fashion. A maximum increase was found 6 min later after the intra-abdominal CO2 administration. Our results disclosed that carboperitoneum during laparoscopy might consistently induce systemic arterial hypertension, and hypercarbia might not be the major determinant factor of hypertension.
authors.affiliation: Department of Anesthesiology, National Cheng-Kung University, Medical College and Hospital, Tainan, Taiwan, R.O.C.
authors.forename: S J
authors.initials: SJ
authors.lastname: Huang
authors.forename: C Y
authors.initials: CY
authors.lastname: Lee
authors.forename: F C
authors.initials: FC
authors.lastname: Yeh
authors.forename: C L
authors.initials: CL
authors.lastname: Chang
mesh_terms: D000328:Adult; D001794:Blood Pressure; D005260:Female; D006339:Heart Rate; D006801:Humans; D006935:Hypercapnia / Q000150:complications*; D006973:Hypertension / Q000209:etiology*; D007431:Intraoperative Complications / Q000209:etiology*; D010535:Laparoscopy / Q000009:adverse effects*