[Pulmonary silicosis and glomerular nephropathy. Apropos of 1 case].
A 43-year-old stone cutter with 13 years of exposure to silica developed a pulmonary silicosis and a glomerulonephritis with moderate renal failure. Renal biopsy demonstrated in light microscopy a segmental and focal mesangial proliferation and in electron microscopy distinct alterations of the proximal tubular cells. Renal histology suggest silica may play a part in the pathogenesis of renal damage. Clinicians should therefore include silica exposure in the differential diagnosis of unexplained glomerulonephritis.
Pouthier
D
D
Département de Néphrologie, Centre Hospitalier de Luxembourg.
Duhoux
P
P
Van Damme
B
B
D000328:Adult; D005920:Glomerular Mesangium / Q000473:pathology; D005921:Glomerulonephritis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology; D007687:Kidney Tubules, Proximal / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D012822:Silicon Dioxide; D012829:Silicosis / Q000150:complications* / Q000473:pathology
D012822:Silicon Dioxide
Silicose pulmonaire et néphropathie glomérulaire. A propos d'un cas.