Primary squamous cell carcinoma of the caecum.
A case of primary squamous cell carcinoma of the caecum arising in a tubulo-villous adenoma is described. This rare lesion develops following genomic derangement of the multipotential colonic stem cells. The literature is reviewed and factors contributing towards squamous cell differentiation discussed.
Wyatt
M G
MG
Department of Surgery, Derriford Hospital, Plymouth, UK.
Clarke
T J
TJ
Teasdale
C
C
D000236:Adenoma / Q000473:pathology*; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002430:Cecal Neoplasms / Q000473:pathology*; D002471:Cell Transformation, Neoplastic; D006801:Humans; D008297:Male; D012307:Risk Factors