title: [Evaluation of the toxicity of particle-bound dioxins and furans in the environment of a metal plant].
abstract: During the last years increased PCDD/PCDF-levels were found in soil, dust and vegetables in a living area close to a metal reclamation plant in Southern Germany. 450 volunteers participated in a clinical and laboratory trial. In a randomised group of 22 persons PCDD/PCDF concentrations have been investigated from blood samples. The range of PCDD/PCDF between 16-80 (mean 31) did not vary substantially from values in non-exposed national samples. Results of clinical history and clinical and laboratory testing did not correlate with emission, time of exposure or PCDD/PCDF concentrations of blood samples. It is suggested that PCDD/PCDF of pyrolytic origin may be incorporated to a lesser extent in humans.
authors.affiliation: Abteilung für Neuroradiologie, Klinikum der Universität Heidelberg.
authors.forename: M
authors.initials: M
authors.lastname: Klett
authors.forename: M
authors.initials: M
authors.lastname: Peper
authors.forename: E
authors.initials: E
authors.lastname: Sennewald
authors.forename: W D
authors.initials: WD
authors.lastname: Heller
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000393:Air Pollutants / Q000009:adverse effects*; D001572:Benzofurans / Q000009:adverse effects / Q000493:pharmacokinetics; D002648:Child; D004147:Dioxins / Q000009:adverse effects* / Q000493:pharmacokinetics; D004391:Dust / Q000009:adverse effects*; D004784:Environmental Monitoring / Q000379:methods*; D005260:Female; D005663:Furans / Q000009:adverse effects* / Q000493:pharmacokinetics; D005858:Germany; D006801:Humans; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D000072317:Polychlorinated Dibenzodioxins / Q000009:adverse effects / Q000031:analogs & derivatives / Q000493:pharmacokinetics; D011108:Polymers / Q000009:adverse effects / Q000493:pharmacokinetics
chemical_list: D000393:Air Pollutants; D001572:Benzofurans; D004147:Dioxins; D004391:Dust; D005663:Furans; D000072317:Polychlorinated Dibenzodioxins; D011108:Polymers; C016068:polychlorodibenzofuran
vernacular_title: Bewertung der Toxizität partikelgebundener Dioxine und Furane im Umfeld einer Metallhütte.