Neurologic complications of nonneuronopathic Gaucher's disease.
We describe eight patients with type 1 Gaucher's disease who developed neurologic complications that were secondary to systemic features of the illness. Four patients experienced neurologic difficulties because of coagulopathy, and the other four patients had involvement of the nervous system secondary to skeletal disease. Early recognition of these complications in patients with type 1 Gaucher's disease may lead to improved neurologic outcome.
Grewal
R P
RP
Developmental and Metabolic Neurology Branch, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health, Bethesda, MD 20892.
Doppelt
S H
SH
Thompson
M A
MA
Katz
D
D
Brady
R O
RO
Barton
N W
NW
D000368:Aged; D005776:Gaucher Disease / Q000150:complications* / Q000473:pathology; D006402:Hematologic Diseases / Q000209:etiology; D006801:Humans; D008297:Male; D009422:Nervous System Diseases / Q000209:etiology* / Q000473:pathology