A case of hepatitis related to etretinate therapy and hepatitis B vaccine.
The case of a 41-year-old male patient is described who developed acute reversible hepatitis related to etretinate therapy. During the course of etretinate he received 2 doses of hepatitis B vaccine; this and his HLA typing A1, A2, Bw57, Cw6 may have predisposed him to develop this reaction.
Green
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C
Department of Dermatology, Ninewells Hospital, Dundee, Scotland.
Lakshmipathi
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T
D000208:Acute Disease; D000328:Adult; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000276:immunology; D005050:Etretinate / Q000009:adverse effects*; D006680:HLA Antigens / Q000032:analysis; D017325:Hepatitis B Vaccines; D006801:Humans; D008297:Male; D011565:Psoriasis / Q000188:drug therapy; D012307:Risk Factors; D014761:Viral Hepatitis Vaccines / Q000008:administration & dosage / Q000009:adverse effects*
D006680:HLA Antigens; D017325:Hepatitis B Vaccines; D014761:Viral Hepatitis Vaccines; D005050:Etretinate