[Changes in the blood rheology and an audiometric deficit in a group of patients exposed to occupational noise pollution].
Several hemorheologic and plasma proteic features were analyzed in workers exposed to acoustic defilement. Whole-blood viscosity was significantly increased (at every shear-rate considered) in patients with severe sensorineural hearing impairment; whereas plasma, serum and relative viscosity remained unchanged. These variations were independent of erythrocyte deformability and aggregation, and of plasma fibrinogen levels, resulted indeed in the normal range. On the contrary plasma fibronectin was significantly increased in patients with sensorineural hearing impairment, suggesting a microvascular endothelial damage in these subjects. The exposition to acoustic defilement during work activity may be considered as aetiological factor for the development and progression of sensorineural hearing impairment, and more extensively for the occurrence of cardiovascular complications.
Solerte
S B
SB
Dipartimento di Medicina Interna e Terapia Medica, Università di Pavia.
Fioravanti
M
M
Ferrari
E
E
Vittadini
G
G
Battaglia
A
A
Candura
F
F
D000328:Adult; D000704:Analysis of Variance; D001299:Audiometry / Q000706:statistics & numerical data; D001809:Blood Viscosity; D006317:Hearing Loss, Noise-Induced / Q000097:blood* / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009623:Noise, Occupational / Q000009:adverse effects* / Q000706:statistics & numerical data; D009784:Occupational Diseases / Q000097:blood* / Q000453:epidemiology / Q000209:etiology; D012044:Regression Analysis
Modificazioni dell'assetto emoreologico e deficit audiometrico in un gruppo di pazienti sottoposti ad inquinamento acustico professionale.