Adsorption of a hydrophobic mutagen to five contrasting dietary fiber preparations.
The ability of five plant cell wall (dietary fiber) preparations with contrasting compositions to adsorb in vitro the hydrophobic, environmental mutagen, 1,8-dinitropyrene (DNP), was investigated. Many of the fruits and vegetables in Western diets are from dicotyledonous (broad leaved) plants and the dietary fiber from these consists mainly of unlignified cell walls. A representative of this wall type, prepared from immature cabbage leaves, showed little ability to adsorb DNP. Two other cell-wall preparations, representing lignified walls of dicotyledons and unlignified walls of vegetative parts of grasses and cereals (monocotyledons belonging to the family Poaceae), adsorbed DNP much more effectively. However, two further preparations, representing suberized walls of cork cells and lignified walls of vegetative parts of grasses and cereals, were the most effective in adsorbing DNP. Extrapolation of these data to the in vivo situation would indicate that increased consumption of the vegetative parts of grasses or cereals and plant material containing cork cells, for example potato skins, could be effective in removing hydrophobic mutagens from potential contact with colonic mucosal cells.
Roberton
A M
AM
Department of Biochemistry, University of Auckland, New Zealand.
Ferguson
L R
LR
Hollands
H J
HJ
Harris
P J
PJ
D001937:Brassica; D004043:Dietary Fiber / Q000737:chemistry*; D008129:Lolium; D009152:Mutagenicity Tests; D009153:Mutagens / Q000737:chemistry*; D011721:Pyrenes / Q000737:chemistry*; D014908:Triticum
D004043:Dietary Fiber; D009153:Mutagens; D011721:Pyrenes; C033310:1,8-dinitropyrene