Phosphate, not superoxide dismutase, facilitates electron transfer from ferrous salts to cytochrome c.
Peterson and Eaton (1989, Biochem. Biophys. Res. Commun. 165, 164-167) reported that the copper- and zinc-containing, but not the manganese-containing, superoxide dismutase catalyzes the reduction of cytochrome c by ferrous salts. This activity, erroneously attributed to the enzyme, is now shown to have been due to inorganic phosphate.
Beyer
W F
WF
Department of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710.
Fridovich
I
I
D000818:Animals; D003574:Cytochrome c Group / Q000378:metabolism*; D004579:Electron Transport / Q000187:drug effects; D005296:Ferrous Compounds / Q000378:metabolism*; D010710:Phosphates / Q000494:pharmacology*; D011188:Potassium / Q000494:pharmacology; D017680:Potassium Compounds; D012710:Serum Albumin, Bovine / Q000494:pharmacology; D013482:Superoxide Dismutase / Q000494:pharmacology*
D003574:Cytochrome c Group; D005296:Ferrous Compounds; D010710:Phosphates; D017680:Potassium Compounds; D012710:Serum Albumin, Bovine; C013216:potassium phosphate; D013482:Superoxide Dismutase; D011188:Potassium