[Isolation and identification of cynanester A from Cynanchum chinense R. Br].
Cynanester A (I) a new triterpenoid ester was isolated, together with lupeol acetate, lignoceric acid and beta-sitosterol, from Cynanchum chinense R. Br. (Asclepiadaceae). The mass spectrum suggested the presence of caproyl group and lupane skeleton with isopropenyl group in the molecule. Alkaline hydrolysis of I with 5% methanolic potassium hydroxide yielded lupeol Ia and n-caproic acid. The acid was esterified with MeOH-H2SO4 to afford methyl caproate, by GLC comparison with authentic sample. The acid was also identified by IR comparison. As above, the structure of cynanester A was established as lupeol caproate.
Wu
Y D
YD
Ningxia Medicinal College, Yinchuan.
Zhang
F Q
FQ
Zhang
M
M
Yan
Q S
QS
Huang
B S
BS
Chen
Z L
ZL
D002208:Caproates / Q000737:chemistry / Q000302:isolation & purification*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D015394:Molecular Structure; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
D002208:Caproates; D004365:Drugs, Chinese Herbal; D014315:Triterpenes; C076447:Cynanester A