Hyperreninemic hypoaldosteronism due to hepatocellular carcinoma metastatic to the adrenal gland.
Metastases to the adrenal glands are common in patients with cancer, but among those affected, hyperreninemic hypoaldosteronism is noted very rarely. A case of hyperreninemic hypoaldosteronism secondary to metastatic hepatocellular carcinoma is reported. Laboratory data revealed selective aldosterone deficiency with hyperreninemia. Biopsy documented replacement of the adrenal glands with metastatic hepatocellular carcinoma. A review of the literature disclosed that the present case was an extremely rare one of its kind.
Otabe
S
S
Department of Gastroenterology, Jichi Medical School, Tochigi, Japan.
Muto
S
S
Asano
Y
Y
Sato
K
K
Ohtani
M
M
Kawamoto
C
C
Ido
K
K
Kimura
K
K
D000310:Adrenal Gland Neoplasms / Q000556:secondary*; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000450:Aldosterone / Q000097:blood; D000804:Angiotensin II / Q000494:pharmacology; D006528:Carcinoma, Hepatocellular / Q000556:secondary*; D005665:Furosemide / Q000494:pharmacology; D006801:Humans; D006994:Hypoaldosteronism / Q000097:blood / Q000209:etiology*; D008113:Liver Neoplasms; D008297:Male; D008875:Middle Aged; D012083:Renin / Q000097:blood*; D000092502:Renin Inhibitors
D000324:Adrenocorticotropic Hormone; D000450:Aldosterone; D000804:Angiotensin II; D005665:Furosemide; D012083:Renin; D000092502:Renin Inhibitors