title: [Effects of atrial natriuretic factor on proliferative response and natural cytotoxicity of human lymphocytes].
abstract: Effect of synthetic analogues of atrial natriuretic factor (ANF) on proliferative response and natural cytotoxic lymphocytes of human subjects was investigated in vitro. ANF-III and ANF-IV increased blast transformation lymphocytes induced by a Con-A suboptimal dose. The increase of cells activity was comparable with the effect of interleukin-2, added at a dose of 50-100 unit/ml.
authors.forename: L A
authors.initials: LA
authors.lastname: Gracheva
authors.forename: E N
authors.initials: EN
authors.lastname: Aleksandrova
authors.forename: E L
authors.initials: EL
authors.lastname: Nasonov
authors.forename: Zh D
authors.initials: ZhD
authors.lastname: Bespalova
authors.forename: M V
authors.initials: MV
authors.lastname: Ovchinnikov
authors.forename: V A
authors.initials: VA
authors.lastname: Vinogradov
authors.forename: M I
authors.initials: MI
authors.lastname: Titov
mesh_terms: D009320:Atrial Natriuretic Factor; D001782:Blood Donors; D002311:Cardiomyopathy, Dilated / Q000276:immunology; D002478:Cells, Cultured; D003208:Concanavalin A / Q000494:pharmacology; D003601:Cytotoxicity Tests, Immunologic; D003602:Cytotoxicity, Immunologic; D006801:Humans; D007376:Interleukin-2 / Q000494:pharmacology; D008213:Lymphocyte Activation / Q000187:drug effects*
chemical_list: D007376:Interleukin-2; C472955:NPPA protein, human; D003208:Concanavalin A; D009320:Atrial Natriuretic Factor
vernacular_title: Vliianie atrial'nogo natriĭureticheskogo faktora na proliferatvnyĭ otvet i estestvennuiu tsitotoksichnost' limfotsitov cheloveka.