title: [A clinical operation of acne vulgaris treated with benzoyl peroxide].
abstract: This paper describes the treatment of 58 patients with acne, including 30 patients treated with 5% benzoyl peroxide cream and 28 patients treated with 0.025% retinoic acid ointment as control. Improvement could be seen after 4 weeks. The efficacy in the test group was 93.3% and that in the control group was 53.5% (P less than 0.001). The early effect was obtained within one week, and no side effects were seen in the test group. Animal test has shown no side effects, including irritation and sensitive reactions with the skin painted with 10% BPC. The conclusion is that 5% BPC is a treatment of choice for patients with acne vulgaris.
authors.affiliation: PUMC Hospital, Beijing.
authors.forename: B
authors.initials: B
authors.lastname: Zhang
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy*; D000293:Adolescent; D000328:Adult; D000818:Animals; D001585:Benzoyl Peroxide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D008297:Male
chemical_list: D001585:Benzoyl Peroxide