title: Serum beta-hexosaminidase in young university students.
abstract: In a sample of 203 first-year university students, serum beta-hexosaminidase (beta-HEX) was studied as a possible marker of heavy drinking. There are no previous studies on beta-HEX in a young nonalcoholic population. All students were healthy and without regular medication except the use of p-pills in 49 of the 123 female students. Alcohol consumption was measured on a frequency-volume scale. Serum beta-HEX did not correlate with reported drinking, gamma-glutamyl transferase (GGT), mean corpuscular volume (MCV) nor alcohol problems. The mean beta-HEX of 26 teetotalers did not differ from that of the heaviest drinking group (n = 25). A new finding was a significant (p = 0.009) increase of serum beta-HEX in female students using oral contraceptives. We conclude that serum beta-HEX is a poor indicator of alcohol consumption in young university students and if elevated the use of p-pills must be considered.
authors.affiliation: Finnish Student Health Service, Helsinki.
authors.forename: M
authors.initials: M
authors.lastname: Nyström
authors.forename: J
authors.initials: J
authors.lastname: Peräsalo
authors.forename: M
authors.initials: M
authors.lastname: Salaspuro
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000503:physiopathology; D000437:Alcoholism / Q000175:diagnosis* / Q000201:enzymology*; D005260:Female; D006801:Humans; D008297:Male; D012016:Reference Values; D013695:Temperance; D001619:beta-N-Acetylhexosaminidases / Q000097:blood*
chemical_list: D001619:beta-N-Acetylhexosaminidases