title: Antibody to human T-lymphotropic virus in a patient with Guillain-Barré syndrome (case report)
abstract: Serum sample obtained from a male, 12 year old patient suffering from Guillain-Barré syndrome (GBS) was positive for human T-lymphotropic virus (HTLV-I) antibody by the enzyme-linked immunosorbent assay (ELISA) and the Western Blot analysis (WB). Attempts to isolate enteroviruses (including poliovirus) from faecal material in both tissue culture and suckling mice were unsuccessful; in addition, acute and convalescent paired serum samples did not show any evidence of recent poliovirus infection when tested against the three serotypes. Specific tests for detection of Epstein-Barr virus infection were not performed; however, the Paul-Bunnel test yielded negative results. ELISA for detection of anti-cytomegalovirus IgM was also negative. The concomitant occurrence of either adult T cell leukemia (ATL) or lymphoma was not recorded in this case.
authors.affiliation: Seção de Vírus do Instituto Evandro Chagas, Fundação Nacional de Saúde, Belém, Pará, Brazil.
authors.forename: C M
authors.initials: CM
authors.lastname: Nakauchi
authors.forename: A C
authors.initials: AC
authors.lastname: Linhares
authors.forename: M L
authors.initials: ML
authors.lastname: Gomes
authors.forename: K
authors.initials: K
authors.lastname: Maruyama
authors.forename: L I
authors.initials: LI
authors.lastname: Kanzaki
authors.forename: V N
authors.initials: VN
authors.lastname: Azevedo
mesh_terms: D015153:Blotting, Western; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay; D015481:HTLV-I Antibodies / Q000032:analysis*; D006801:Humans; D008297:Male; D011129:Polyradiculoneuropathy / Q000276:immunology*
chemical_list: D015481:HTLV-I Antibodies