Urine-blood carbon dioxide tension gradient in healthy dogs.
The urine-blood carbon dioxide tension (PCO2) gradient was measured in 10 healthy mature Beagles after alkalinization of the urine by administration of sodium bicarbonate. The mean (+/- SD) urine-blood PCO2 gradient was 65.92 +/- 14.42 mm of Hg, with range of 38.2 to 82.2 mm of Hg. Mean urine PCO2 was 110.21 +/- 14.19 mm of Hg, with range of 84.1 to 127.3 mm of Hg. Because urine-blood PCO 2 gradient less than 30.0 mm of Hg or urine PCO2 less than 55 mm of Hg in people is diagnostic for a defect in distal nephron acidification, similar values might be applicable to diseases in dogs.
Shaw
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Department of Companion Animals, Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, Canada.
D000818:Animals; D001639:Bicarbonates / Q000008:administration & dosage; D001785:Blood Gas Monitoring, Transcutaneous / Q000662:veterinary*; D002245:Carbon Dioxide / Q000097:blood / Q000652:urine*; D004285:Dogs; D005260:Female; D008297:Male; D012964:Sodium / Q000008:administration & dosage; D017693:Sodium Bicarbonate; D013997:Time Factors
D001639:Bicarbonates; D002245:Carbon Dioxide; D017693:Sodium Bicarbonate; D012964:Sodium