New directions in managing chemotherapy-related emesis.
The author reviews the physiology of the various types of emesis and the factors that influence chemotherapy-induced nausea and vomiting, including both patient-related factors and those related to treatment. He then enumerates and describes the antiemetic agents now available, ranging from phenothiazines to cannabinoids and serotonin (5-hydroxytryptamine) antagonists; explains how they might best be used; and outlines the probable future direction for antiemetic studies.
Krasnow
S H
SH
Oncology Section, Washington VA Medical Center.
D000932:Antiemetics / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D014839:Vomiting / Q000139:chemically induced* / Q000188:drug therapy*
D000932:Antiemetics; D000970:Antineoplastic Agents