Bedside blood ketone body monitoring.
The use of a reagent strip and reflectance meter for the bedside measurement of 3-hydroxybutyrate during the clinical management of diabetic ketoacidosis is described. Comparison of this method with a laboratory enzymatic assay shows good correlation (r = 0.97, p less than 0.05). Initial use in acute ketoacidosis suggests that knowledge of hourly changes in 3-hydroxybutyrate levels could be helpful in determining the optimum insulin dose.
McBride
M O
MO
Sir George E. Clark Metabolic Unit, Royal Victoria Hospital, Belfast, UK.
Smye
M
M
Nesbitt
G S
GS
Hadden
D R
DR
D020155:3-Hydroxybutyric Acid; D001786:Blood Glucose / Q000032:analysis; D016883:Diabetic Ketoacidosis / Q000097:blood* / Q000188:drug therapy; D006801:Humans; D006885:Hydroxybutyrates / Q000097:blood*; D007328:Insulin / Q000627:therapeutic use; D008991:Monitoring, Physiologic / Q000379:methods; D011934:Reagent Strips; D013997:Time Factors
D001786:Blood Glucose; D006885:Hydroxybutyrates; D007328:Insulin; D011934:Reagent Strips; D020155:3-Hydroxybutyric Acid