[H-reflex in spastic patients due to spinal cord injury before and after the use of diazepam and baclofen].
This paper concerns the "H" reflex in eleven patients with spastic spinal cord injury (C5-T10), treated with Baclofen (50 mg/day) or Diazepam (20 mg/day). The "H" reflex was tested in the tibial nerve before and 15 days after the interrupted use of the drugs. Five patients used Baclofen and 6 patients used Diazepam. The latency time was measured. All the patients showed normal latency time before the use of the drugs. After the use all but one didn't show any significant alterations of the latency time. The patient, who showed a greater latency after use of drugs, presented an improvement of the motor function.
Greve
J M
JM
Divisão de Reabilitação de Vergueiro, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo.
Ribeiro
J B
JB
Camargo
A J
AJ
Chiovato
J
J
Battistella
L R
LR
Barros Filho
T E
TE
D000328:Adult; D001418:Baclofen / Q000494:pharmacology*; D003975:Diazepam / Q000494:pharmacology*; D006181:H-Reflex / Q000187:drug effects*; D006801:Humans; D008297:Male; D009128:Muscle Spasticity / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology*; D011930:Reaction Time; D013119:Spinal Cord Injuries / Q000150:complications / Q000503:physiopathology*
D001418:Baclofen; D003975:Diazepam
Pesquisa do reflexo "H" em pacientes espásticos por lesão medular antes e depois do uso de diazepam e baclofen.