Correlation of histopathological and clinical findings in neuromuscular diseases.
Our file comprises bioptic and necroptic materials of skeletal muscles: progressive spinal muscle atrophy of adults 16, amyotrophic lateral sclerosis 12, infantile progressive spinal amyotrophy Werdnig-Hoffmann 9, chronic progressive amyotrophy Oppenheim 6, syringomyelia and syringobulbia 3, conditions after spinal cord accidents. Diagnosis was difficult because one time the neurological marks were at the head and other time the muscular ones. In the clinical picture there was muscle weakness and atrophy, the spontaneous and palpation painfulness was missing. Muscle weakness und its intensity did not correspond to the degree of muscle atrophies. The discrepancies of electromyographic and histopathologic pictures are explained by occurrence of so-called concomitant myopathies, which arise most probably from the disorders of histioceptive-proprioceptive system.
Rozhold
O
O
Institute of Clinical and Experimental Neurology, Palacký University, Olomouc.
Vojácek
K
K
D004576:Electromyography; D006801:Humans; D009132:Muscles / Q000473:pathology* / Q000503:physiopathology; D009468:Neuromuscular Diseases / Q000473:pathology* / Q000503:physiopathology