title: Effects of 250 and 500 Hz tone exposure on the inner ear of guinea pigs as determined by electrophysiological techniques.
abstract: The electrophysiological study of cochlear microphonics (CM), whole nerve action potential (AP) and endocochlear potential (EP) were examined. (1) With the extension of the exposure time of 500 Hz tone, a decrease of CM maximum output voltage in test frequency from 2 to 6 kHz was observed. (2) N1 potential of AP decreased very significantly by 500 Hz tone exposure. (3) A very pronounced decrease of the absolute value of the negative potential of the EP in 500 Hz exposure was seen.
authors.affiliation: Department of Otorhinolaryngology, Asahikawa Medical College, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Fujita
authors.forename: T
authors.initials: T
authors.lastname: Sugisawa
authors.forename: T
authors.initials: T
authors.lastname: Matsui
authors.forename: M
authors.initials: M
authors.lastname: Takahashi
authors.forename: N
authors.initials: N
authors.lastname: Inada
authors.forename: A
authors.initials: A
authors.lastname: Ishida
authors.forename: K
authors.initials: K
authors.lastname: Yamamura
mesh_terms: D000200:Action Potentials / Q000502:physiology; D000818:Animals; D003051:Cochlea / Q000502:physiology*; D003055:Cochlear Microphonic Potentials / Q000502:physiology; D005072:Evoked Potentials, Auditory / Q000502:physiology; D006168:Guinea Pigs; D006317:Hearing Loss, Noise-Induced / Q000209:etiology; D009622:Noise