title: Residues of organochlorine pesticides in fish, crab and sediment from El Temsah Lake, Suez Canal, Egypt and their effect on mitochondrial ATPase of the New Zealand white rabbit.
abstract: Residues of organochlorine pesticides were monitored in the muscles of Bolti fish Tilapia zillii, the crab Lupa pelagicus and sediment samples collected from El Temsah lake around Ismailia using gas liquid chromatography. The beta isomer of hexachlorocyclohexane (beta.HCH) was the most dominant compound detected in all samples, followed by P, P-DDE and P, P-DDT. Results showed the crab to contain higher concentrations of organochlorine in comparison to concentrations detected in fish muscles. The In-vitro effect of the residues extracted from fish, and crab on the mitochondrial brain and liver ATPase of the New Zealand white rabbit Orcytolagus cuniculus was also studied. Residues of organochlorine pesticides have induced activation in the ATPase enzyme system of both brain and liver. The mixtures of organochlorine residues of both fish and crab were able to activate liver ATPase more than brain ATPase. The present study was conducted to extrapolate possible effects incurred on man if consumed such food.
authors.affiliation: Plant Protection Department, Faculty of Agriculture, Suez Canal University, Ismailia, Egypt.
authors.forename: M T
authors.initials: MT
authors.lastname: Ahmed
authors.forename: S M
authors.initials: SM
authors.lastname: Ismail
mesh_terms: D000251:Adenosine Triphosphatases / Q000187:drug effects*; D000818:Animals; D003386:Brachyura; D004534:Egypt; D004784:Environmental Monitoring; D005069:Evaluation Studies as Topic; D005399:Fishes; D006843:Hydrocarbons, Chlorinated; D007306:Insecticides / Q000009:adverse effects* / Q000032:analysis; D008928:Mitochondria / Q000187:drug effects*; D011817:Rabbits; D014877:Water Pollution, Chemical / Q000032:analysis*
chemical_list: D006843:Hydrocarbons, Chlorinated; D007306:Insecticides; D000251:Adenosine Triphosphatases