title: Effect of Tween 80 and dimethyl sulfoxide on biosynthesis of L-lysine in regulatory mutants of Corynebacterium glutamicum.
abstract: By using dimethyl sulfoxide or Tween 80 (1 or 0.2%), the production of L-lysine was increased by 20-28 and 23-25%, respectively, in regulatory mutant strains of Corynebacterium glutamicum. The stimulation observed is supposed to be caused by influencing cellular surface structures.
authors.affiliation: Institute of Microbiology, Czechoslovak Academy of Sciences, Prague.
authors.forename: J
authors.initials: J
authors.lastname: Konícek
authors.forename: F
authors.initials: F
authors.lastname: Smékal
authors.forename: M
authors.initials: M
authors.lastname: Konícková-Radochová
mesh_terms: D003352:Corynebacterium / Q000187:drug effects / Q000235:genetics / Q000378:metabolism*; D004121:Dimethyl Sulfoxide / Q000494:pharmacology; D008239:Lysine / Q000096:biosynthesis*; D009154:Mutation; D011136:Polysorbates / Q000494:pharmacology
chemical_list: D011136:Polysorbates; D008239:Lysine; D004121:Dimethyl Sulfoxide