Synthesis of the nucleoside analogues of 3-deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN).
Several mono- and di-saccharide nucleoside analogues of 3-deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN, 1) were synthesized under Vorbrüggen, Williamson and Koenigs-Knorr reaction conditions. The stereochemistry at the anomeric position of these compounds were elucidated by means of NMR and acid catalyzed hydrolysis.
Nakamura
M
M
School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan.
Fujita
S
S
Furuhata
K
K
Ogura
H
H
D002240:Carbohydrate Sequence; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism; D013400:Sugar Acids / Q000737:chemistry*
D009705:Nucleosides; D013400:Sugar Acids; C050008:3-deoxyglycero-galacto-nonulosonic acid