Spironolactone in dermatologic therapy.
In the treatment of androgen-mediated skin disorders spironolactone provides a valuable therapeutic option. This article reviews the use of spironolactone as an antiandrogen in dermatologic therapy. The endocrinologic effects, pharmacology, dermatologic uses, and side effects are discussed, and guidelines for its use are provided.
Shaw
J C
JC
Department of Dermatology, Oregon Health Sciences University, Portland.
D000152:Acne Vulgaris / Q000188:drug therapy; D000818:Animals; D004702:Endocrine Glands / Q000187:drug effects; D006628:Hirsutism / Q000188:drug therapy; D006801:Humans; D012871:Skin Diseases / Q000188:drug therapy*; D013148:Spironolactone / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
D013148:Spironolactone