title: [Color-coded duplex sonography and ultrasound contrast media--detection of renal perfusion defects in experimental animals].
abstract: The diagnostic use of microbubble consisting transpulmonary ultrasound contrast media in combination with color-coded duplex sonography (CCDS) has not been evaluated. Perfusion of the orthotopic kidney was therefore examined in an animal experiment with CCDS and transpulmonary echocontrast agent. The contrast agent consists of tiny stabilized air bubbles which survive the lung passage after peripheral venous injection and cause echo-enhancement of the arterial blood. The combination of CCDS and this contrast agent permits demonstration of the renal perfusion including the peripheral parenchyma. Even small experimental perfusion defects can be identified by this method. The use of this contrast agent in combination with CCDS might contribute significantly to the diagnostic potential of ultrasound.
authors.affiliation: Abteilung für Röntgendiagnostik, FU Berlin, Klinkum Steglitz.
authors.forename: F
authors.initials: F
authors.lastname: Fobbe
authors.forename: J
authors.initials: J
authors.lastname: Siegert
authors.forename: T
authors.initials: T
authors.lastname: Fritzsch
authors.forename: H C
authors.initials: HC
authors.lastname: Koch
authors.forename: K J
authors.initials: KJ
authors.lastname: Wolf
mesh_terms: D000818:Animals; D003287:Contrast Media / Q000008:administration & dosage; D004285:Dogs; D007275:Injections, Intravenous; D007668:Kidney / Q000098:blood supply* / Q000000981:diagnostic imaging; D011134:Polysaccharides / Q000008:administration & dosage; D013535:Suspensions; D014463:Ultrasonography
chemical_list: D003287:Contrast Media; D011134:Polysaccharides; D013535:Suspensions; C059891:SHU 508
vernacular_title: Farbkodierte Duplexsonographie und Ultraschallkontrastmittel--Nachweis von renalen Perfusionsdefekten im Tierexperiment.