[Nucleolus organizer regions and ploidy pattern of DNA in stomach neoplasms].
We studied 20 gastric adenocarcinoma to determine DNA ploidy pattern by flow cytometry and nucleolar organizer regions by the colloidal silver method. There were 12 diffuse and 8 intestinal type lesions. 11 tumors were classified as diploid and 9 as aneuploid. No correlation was observed between DNA ploidy pattern and mean number of nucleolar organizer regions. The histologic type was significantly related to the number of nucleolar organizer regions (p < 0.01). Poorly differentiated lesions had significantly less nucleolar organizer regions than intestinal type lesions. Lesions with ring cells (n = 6) had similar number of nucleolar organizer regions than poorly differentiated lesions.
Roa
I
I
Unidad de Anatomía Patológica y Citopatología, Facultad de Medicina, Universidad de La Frontera, Hospital Regional de Temuco, Chile.
Araya
J C
JC
de Aretxabala
X
X
Wistuba
I
I
Villaseca
M
M
D000230:Adenocarcinoma / Q000648:ultrastructure*; D004273:DNA, Neoplasm / Q000032:analysis*; D005434:Flow Cytometry; D006801:Humans; D009697:Nucleolus Organizer Region / Q000473:pathology*; D011003:Ploidies; D013274:Stomach Neoplasms / Q000648:ultrastructure*
D004273:DNA, Neoplasm
Regiones del organizador nucleolar y patrón de ploidía del ADN en el cáncer gástrico.