Neuropathy following acute intoxication with Mecarbam (OP ester)
Only a small number of organophosphorous compounds, of the many thousands circulating on the market, has been reported as causing neuropathy with delayed onset. A case is presented of a young male who in an attempt to commit suicide by taking a massive dose of Mecarbam, developed polyneuropathy accompanied by a mild involvement of the CNS. Mecarbam is herewith reported for the first time as an agent which can affect the peripheral nervous system.
Stamboulis
E
E
Department of Neurology, University of Athens, Greece.
Psimaras
A
A
Vassilopoulos
D
D
Davaki
P
P
Manta
P
P
Kapaki
E
E
D000328:Adult; D004305:Dose-Response Relationship, Drug; D004576:Electromyography / Q000187:drug effects; D005500:Follow-Up Studies; D006801:Humans; D007306:Insecticides; D008297:Male; D009046:Motor Neurons / Q000187:drug effects; D009460:Neurologic Examination; D009468:Neuromuscular Diseases / Q000139:chemically induced* / Q000175:diagnosis; D062025:Organophosphate Poisoning; D063086:Organothiophosphates; D011930:Reaction Time / Q000187:drug effects; D013406:Suicide, Attempted; D009435:Synaptic Transmission / Q000187:drug effects
D007306:Insecticides; D063086:Organothiophosphates; C054137:mecarbam