Allergic contact dermatitis from 4-chloro-7-nitrobenzofurazan.
A 30-year-old pharmacist suffered from acute allergic contact dermatitis due to 4-chloro-7-nitrobenzofurazan (NBD-Cl). Contact allergy towards this reagent and 2 of its reaction products was proven by patch tests. As NBD-Cl has not been reported as an allergen before, the characteristics of this chemical and its use as an analytical reagent are briefly surveyed. Similarities to dinitrochlorobenzene (DNCB) are pointed out.
Brasch
J
J
Department of Dermatology, University of Kiel, FRG.
D000208:Acute Disease; D000328:Adult; D001572:Benzofurans / Q000009:adverse effects* / Q000737:chemistry; D003877:Dermatitis, Contact / Q000188:drug therapy / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000139:chemically induced* / Q000188:drug therapy; D005260:Female; D006801:Humans; D011223:Praziquantel / Q000009:adverse effects / Q000737:chemistry
D001572:Benzofurans; C043708:7-chloro-4-nitrobenzofuran; D011223:Praziquantel