[Fractionation of a chalone-containing substance from Ehrlich's ascites tumor using high pressure chromatography].
The effect of various fractions of chalone--containing preparation from ascyte Ehrlich's tumour obtained by high performance liquid chromatography (HPLC) on mitotic activity and DNA synthesis in the tumour has been studied. After filtration the division of active chalone component which inhibits entering cells into M-phase and S-phase took place. The component inhibiting DNA synthesis eluated with G1-chalone.
Popova
N Ia
NIa
Antokhin
A I
AI
Adrianov
N V
NV
Tret'iakova
L Z
LZ
Romanov
Iu A
IuA
D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D004247:DNA / Q000096:biosynthesis / Q000187:drug effects; D006131:Growth Inhibitors / Q000032:analysis* / Q000494:pharmacology; D008297:Male; D051379:Mice; D008938:Mitosis / Q000187:drug effects; D016196:S Phase / Q000187:drug effects
D006131:Growth Inhibitors; D004247:DNA
Fraktsionirovanie keĭlonsoderzhashchego preparata iz astsitnoĭ opukholi érlikha s pomoshch'iu khromatografii vysodogo davleniia.