Anti-trichomonad IgA antibodies in trichomoniasis before and after treatment.
Anti-trichomonad IgA antibodies were estimated by enzyme-linked immunosorbent assay (ELISA) in serum and vaginal secretions of 25 symptomatic and 25 asymptomatic Trichomonas vaginalis positive patients before and after treatment and in 25 age-matched controls. Significantly higher levels of antitrichomonad IgA antibodies were found in T. vaginalis positive patients when compared to control subjects, especially in vaginal secretions. In addition, a significant decrease in these antibodies was observed after treatment, which was more pronounced in vaginal secretions. It seems that anti-trichomonad IgA antibodies in serum and more so in vaginal secretions are directly related to and specific to the presence of T. vaginalis in the urogenital tract.
Sharma
P
P
Department of Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Malla
N
N
Gupta
I
I
Ganguly
N K
NK
Mahajan
R C
RC
D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D014247:Trichomonas Vaginitis / Q000188:drug therapy / Q000276:immunology*; D014246:Trichomonas vaginalis / Q000276:immunology*
D000913:Antibodies, Protozoan; D007070:Immunoglobulin A