title: Immunological treatment of cough occurring in dogs with dirofilariosis.
abstract: A persistent, spasmic and productive cough known as filarial cough often occurs in dogs with dirofilariosis, and has been considered to be the consequence of an allergic response to Dirofilaria immitis. Twenty-one dogs with filarial cough were subcutaneously injected with worm antigen (200 micrograms of protein concentration) extracted from adult D. immitis once a day for 5 days. These injections were effective for 17 (81%) of the dogs, resulting in a complete cure for 7 dogs and marked improvement for 10 dogs.
authors.affiliation: Department of Internal Medicine and Parasitology, School of Veterinary Medicine, Tokyo University of Agriculture and Technology, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Hayasaki
authors.forename: A
authors.initials: A
authors.lastname: Harayama
authors.forename: H
authors.initials: H
authors.lastname: Seki
authors.forename: K
authors.initials: K
authors.lastname: Konno
authors.forename: I
authors.initials: I
authors.lastname: Ohishi
mesh_terms: D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood; D000947:Antigens, Helminth / Q000627:therapeutic use*; D003371:Cough / Q000209:etiology / Q000628:therapy / Q000662:veterinary*; D004183:Dirofilaria immitis / Q000276:immunology*; D004184:Dirofilariasis / Q000150:complications / Q000662:veterinary*; D004283:Dog Diseases / Q000209:etiology / Q000628:therapy*; D004285:Dogs; D005260:Female; D005455:Fluorescent Antibody Technique; D006386:Hemagglutination Tests; D008297:Male
chemical_list: D000909:Antibodies, Helminth; D000947:Antigens, Helminth