A comparison of azapropazone and aspirin for pain relief following dental extractions.
Eighty patients received one of three treatments after elective dental surgery involving multiple extractions. Group A received aspirin 600 mg, group B azapropazone 300 mg and group C azapropazone 600 mg. All drugs were administered in a double-blind fashion. Quality of analgesia was unsatisfactory for all treatments; over 30% of patients required supplementary analgesia with an opioid. In addition there were a large number of withdrawals from the study. There were no significant differences in analgesic efficacy between groups.
Garrioch
M A
MA
University Department of Anaesthesia, Glasgow Royal Infirmary, Scotland.
Wardall
G J
GJ
Fitch
W
W
D000293:Adolescent; D000328:Adult; D001032:Apazone / Q000009:adverse effects / Q000097:blood / Q000627:therapeutic use*; D001241:Aspirin / Q000009:adverse effects / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy*; D014081:Tooth Extraction / Q000009:adverse effects*
D009020:Morphine; D001032:Apazone; D001241:Aspirin