title: [The adjuvant chemotherapy of patients with colorectal carcinoma (preliminary report)].
abstract: Aim of the present study is to evaluate the role of adjuvant chemotherapy in radically operated patients with colorectal cancer. Included in the study were 55 patients (30 men and 25 women). Radical operation war performed in 24 patients with colonic cancer and in 31 patients with rectal cancer. An average of five courses of chemotherapy were performed after the operation. The observation period for 45 patients was more than 2 years, in 18 of them being more than 5 years. Progression of the disease occurred in 9 patients (16 per cent): 4 with colonic carcinoma and 5 with rectal carcinoma. Evidence of progression was invariably recorded before the end of the second year after the operation. The results tended to be more encouraging after application of the combination Vincristin+CCHO+Ftoruracyl as compared to the use of other combination. The study is in progress.
authors.forename: V
authors.initials: V
authors.lastname: Tsekova
authors.forename: K
authors.initials: K
authors.lastname: Koĭnov
authors.forename: M
authors.initials: M
authors.lastname: Velikova
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002277:Carcinoma / Q000188:drug therapy* / Q000453:epidemiology / Q000473:pathology; D017024:Chemotherapy, Adjuvant; D003082:Colectomy; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000453:epidemiology / Q000473:pathology; D003520:Cyclophosphamide / Q000008:administration & dosage; D004341:Drug Evaluation; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D009367:Neoplasm Staging; D012007:Rectum / Q000601:surgery; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D000970:Antineoplastic Agents; D016685:Mitomycin; D014750:Vincristine; D003520:Cyclophosphamide; D005472:Fluorouracil
vernacular_title: Adiuvantna khimioterapiia pri bolni s kolorektalen kartsinom (predvaritelno sŭobshtenie).