title: [Presymptomatic diagnosis in Huntington chorea families using the gene amplification technique].
abstract: The presymptomatic diagnosis of Huntington chorea (HC) by genic amplification (PCR: polymerase chain reaction) of a DNA G8 sequence containing a polymorphic HindIII site was tested in a particular HC genealogy. The advantage of this method are discussed.
authors.affiliation: Laboratoire d'Anthropologie Physique, Collège de France, Paris.
authors.forename: G
authors.initials: G
authors.lastname: Lucotte
authors.forename: S
authors.initials: S
authors.lastname: Berriche
authors.forename: M C
authors.initials: MC
authors.lastname: Petit
authors.forename: A
authors.initials: A
authors.lastname: Burckel
authors.forename: J C
authors.initials: JC
authors.lastname: Turpin
mesh_terms: D005784:Gene Amplification / Q000235:genetics; D006801:Humans; D006816:Huntington Disease / Q000175:diagnosis* / Q000235:genetics; D021141:Nucleic Acid Amplification Techniques; D010375:Pedigree
vernacular_title: Diagnostic présymptomatique dans les familles de chorée de Huntington par utilisation de la technique d'amplification génique.