title: [Primary germinal tumors of the central nervous system].
abstract: Primary intra-cranial germ-cell tumors are a rare and heterogeneous group of neoplasms, identical to germ-cell tumors of gonads and other organs. These tumors arise along the midline, from the supra-sellar cistern to the pineal gland, and have neurological, ophthalmological, and endocrinological expression. The diagnosis is established by detection of increased levels of tumoral markers and/or by histological examination. The treatment includes chemotherapy, radiotherapy and surgery.
authors.affiliation: Service de médicine infantile, Grenoble, France.
authors.forename: D
authors.initials: D
authors.lastname: Plantaz
authors.forename: C
authors.initials: C
authors.lastname: Bachelot
authors.forename: A
authors.initials: A
authors.lastname: Joannard
authors.forename: A
authors.initials: A
authors.lastname: Benabid
authors.forename: P
authors.initials: P
authors.lastname: Baudain
authors.forename: B
authors.initials: B
authors.lastname: Pasquier
authors.forename: M
authors.initials: M
authors.lastname: Bost
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology; D002493:Central Nervous System Diseases / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D002648:Child; D006801:Humans; D009373:Neoplasms, Germ Cell and Embryonal / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D009423:Nervous System Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy
vernacular_title: Tumeurs germinales primitives du système nerveux central.