title: Quinolinic acid: effect on 45Ca content in perfused rat heart preparations and its calcium ion binding property in Krebs-Henseleit medium and blood serum.
abstract: In the experiment it was found that quinolinic acid perfusion was accompanied with the increase in calcium 45Ca content in myocardium tissue. The increase in calcium content was associated with a decrease in heart contractility. Moreover, it was shown that quinolinic acid can form complexes with calcium ions in Krebs-Henseleit medium as well as in blood serum but only to a small degree.
authors.affiliation: Medical Centre of Postgraduate Education, Laboratory of Histochemistry, Warsaw, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Beskid
authors.forename: L
authors.initials: L
authors.lastname: Finkiewicz-Murawiejska
authors.forename: Z
authors.initials: Z
authors.lastname: Obminski
authors.forename: B
authors.initials: B
authors.lastname: Wolska
mesh_terms: D000818:Animals; D001798:Blood Proteins / Q000494:pharmacology*; D002118:Calcium / Q000032:analysis* / Q000097:blood / Q000378:metabolism; D002132:Calcium Radioisotopes; D000252:Calcium-Transporting ATPases / Q000378:metabolism; D003470:Culture Media / Q000494:pharmacology*; D006321:Heart / Q000187:drug effects*; D006651:Histocytochemistry; D009206:Myocardium / Q000737:chemistry* / Q000378:metabolism; D010477:Perfusion; D011805:Quinolinic Acids / Q000494:pharmacology*; D051381:Rats; D013385:Succinate Dehydrogenase / Q000378:metabolism
chemical_list: D001798:Blood Proteins; D002132:Calcium Radioisotopes; D003470:Culture Media; D011805:Quinolinic Acids; D013385:Succinate Dehydrogenase; D000252:Calcium-Transporting ATPases; D002118:Calcium