title: A study of short term lipoprotein changes induced by single high cholesterol diet in healthy and diseases human volunteers.
abstract: Changes in lipid lipoprotein profile were observed in the first and third hours after feeding 750 mg of egg cholesterol in 13 healthy male subjects (Group A), 6 patients of coronary artery disease (Group B), 10 diabetic patients (Group C), and 10 hypertensive patients (Group D), all belonging to the age group of 35-60 years. 61.53% of healthy male subjects showed a fall in the total serum cholesterol (STC) in the first hour after feeding, while in the rest there was a rise. On the other hand, 66.67% of coronary artery disease patients, 50% of diabetics and 50% hypertensives showed a rise in the first hour while the rest showed either a fall or no change in STC. All groups showed a fall in LDL at the first hour. In the third hour the STC and LDL level increased in group A, C and D, whereas in group B STC showed a fall and LDL showed a rise. All these changes were, however, statistically insignificant. The changes in HDL values were also statistically insignificant except in group D where they showed a progressive rise increase in the first and third hours.
authors.affiliation: Dept. of Medicine, MLB Medical College, Jhansi, India.
authors.forename: R C
authors.initials: RC
authors.lastname: Arora
authors.forename: N
authors.initials: N
authors.lastname: Agarwal
authors.forename: D K
authors.initials: DK
authors.lastname: Singh
mesh_terms: D000328:Adult; D002791:Cholesterol, Dietary / Q000494:pharmacology*; D003327:Coronary Disease / Q000097:blood; D003920:Diabetes Mellitus / Q000097:blood; D006801:Humans; D006973:Hypertension / Q000097:blood; D008074:Lipoproteins / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008077:Lipoproteins, LDL / Q000097:blood; D008079:Lipoproteins, VLDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D014280:Triglycerides / Q000097:blood
chemical_list: D002791:Cholesterol, Dietary; D008074:Lipoproteins; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D008079:Lipoproteins, VLDL; D014280:Triglycerides