title: Tc-99m HIDA hepatobiliary agent in the diagnosis of pulmonary metastasis from hepatocellular carcinoma.
abstract: Twelve patients with hepatocellular carcinoma and multiple metastatic pulmonary nodules were studied with Tc-99m HIDA imaging. Lung scanning was performed 1, 2, 3, 4, and 5 hours after administration of 6 mCi of Tc-99m HIDA with a preset count format of 400 K. In two patients, pulmonary uptake was clearly seen at 1 hour; in the other two patients, uptake could not be detected until 3 hours later. The overall detection rate of 33% suggests that Tc-99m HIDA has limited usefulness as a routine diagnostic tool in the detection of hepatoma metastases. The uptake may include both specific and nonspecific mechanisms.
authors.affiliation: Department of Nuclear Medicine and Internal Medicine, Chang Gung Memorial Hospital, Chang Gung Medical College, Taiwan, Republic of China.
authors.forename: P W
authors.initials: PW
authors.lastname: Wang
authors.forename: D I
authors.initials: DI
authors.lastname: Tai
authors.forename: H Y
authors.initials: HY
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000556:secondary*; D005260:Female; D006801:Humans; D007098:Imino Acids; D008113:Liver Neoplasms / Q000000981:diagnostic imaging*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011877:Radionuclide Imaging; D019780:Technetium Tc 99m Lidofenin
chemical_list: D007098:Imino Acids; D015609:Organotechnetium Compounds; D019780:Technetium Tc 99m Lidofenin