Dark adapted thresholds in young RCS rats.
The dark adapted thresholds of black-eyed RCS rats and cogenic controls were measured using a new psychophysical procedure that permits determination of thresholds at earlier ages than previously possible. Rats were tested longitudinally between about ages 1 and 3 months. At all ages, thresholds of RCS rats were higher than those of controls. Thresholds did not change systematically with age for either RCS rats or controls. At age 3 months, when the RCS rats' b-wave is no longer recordable, RCS thresholds are about 2.2 log units higher than those of controls.
Kurylo
D D
DD
Department of Ophthalmology, Children's Hospital, Boston, MA.
Hansen
R M
RM
Fulton
A B
AB
D000375:Aging / Q000502:physiology; D000818:Animals; D003623:Dark Adaptation; D011601:Psychophysics; D051381:Rats; D011922:Rats, Mutant Strains; D012162:Retinal Degeneration / Q000503:physiopathology*; D012684:Sensory Thresholds; D014796:Visual Perception / Q000502:physiology*