title: Remaining problems in the treatment of patients with Wilms' tumor.
abstract: Major advances have been made in the treatment of children with Wilms' tumor. Remaining areas of investigation include the role of adriamycin and the treatment of children with stage III and IV disease and the role of whole lung radiation therapy in the treatment of children with pulmonary metastases. Long-term follow up of successfully treated patients will provide valuable insight into the importance of genetic factors in the cause of Wilms' tumor.
authors.affiliation: Department of Pediatrics, Roswell Park Cancer Institute, Buffalo, New York.
authors.forename: D M
authors.initials: DM
authors.lastname: Green
authors.forename: J Z
authors.initials: JZ
authors.lastname: Finklestein
authors.forename: N E
authors.initials: NE
authors.lastname: Breslow
authors.forename: J B
authors.initials: JB
authors.lastname: Beckwith
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D003131:Combined Modality Therapy; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology / Q000628:therapy*; D009367:Neoplasm Staging; D009392:Nephrectomy; D011379:Prognosis; D011878:Radiotherapy / Q000009:adverse effects; D009396:Wilms Tumor / Q000473:pathology / Q000628:therapy*