title: [Biomechanic study of the tensile strength of lyophilized and deep frozen human Achilles tendons following gamma and ethylene oxide sterilization].
abstract: By a failed first operation allogenic tissues, as human Achilles tendons are offered for anterior cruciate ligament replacement. The effects of freeze-drying and primary Gamma- or EO-sterilization on the mechanical properties of 62 complete and 74 bisected tendons again fresh frozen controls were investigated under axial tension. A significant decrease of tensile strength for the freeze-dried preparations of 33% for the whole and 43% for the bisected tendons were observed, while Gamma- or EO-sterilizations showed a smaller deleterious effect on the tendons. Considering only the primary mechanical strength complete freeze-dried or complete and bisected irradiated Achilles tendons show sufficient tensile strength for anterior cruciate ligament replacement.
authors.affiliation: Zentrum Operative Medizin II, Philipps-Universität, Marburg.
authors.forename: G
authors.initials: G
authors.lastname: Rauch
authors.forename: M
authors.initials: M
authors.lastname: Gerbersdorf
authors.forename: P
authors.initials: P
authors.lastname: Dörner
authors.forename: M
authors.initials: M
authors.lastname: Lengsfeld
authors.forename: P
authors.initials: P
authors.lastname: Griss
mesh_terms: D000125:Achilles Tendon / Q000187:drug effects / Q000503:physiopathology / Q000528:radiation effects / Q000637:transplantation*; D016118:Anterior Cruciate Ligament / Q000601:surgery*; D000070598:Anterior Cruciate Ligament Injuries; D001705:Bioprosthesis; D015925:Cryopreservation; D005027:Ethylene Oxide; D005612:Freeze Drying; D005720:Gamma Rays; D006801:Humans; D007718:Knee Injuries / Q000601:surgery*; D011183:Postoperative Complications / Q000601:surgery*; D013242:Sterilization; D013718:Tensile Strength; D014021:Tissue Preservation
chemical_list: D005027:Ethylene Oxide
vernacular_title: Biomechanische Untersuchung über die Zugfestigkeit lyophilisierter und tiefgefrorener humaner Achillessehnen nach Gamma- und Ethylenoxid-Sterilisation.