[Influence of muscarinic receptors and calcium channel blockers on bronchial reactivity and ventilation parameters in patients with obstructive lung diseases].
In 9 patients with obstructive lung disease as influence of ipratropium bromide (Atrovent) - muscarine receptors blocker and verapamil - calcium channel blocker on bronchial reactivity was evaluated. In the study was documented that verapamil decreased the bronchial reactivity and didn't change static ventilation parameters. Atrovent in observed patients improved their ventilation. On the other hand, verapamil didn't change a mode and efficiency of Atrovent action.
Siergiejko
Z
Z
Kliniki Alergologii AM, Białymstoku.
Kazberuk
M
M
Hofman
J
J
Chyrek-Borowska
S
S
D016535:Bronchial Hyperreactivity / Q000188:drug therapy*; D006801:Humans; D009241:Ipratropium / Q000627:therapeutic use*; D008173:Lung Diseases, Obstructive / Q000503:physiopathology*; D012129:Respiratory Function Tests; D014700:Verapamil / Q000627:therapeutic use*
D014700:Verapamil; D009241:Ipratropium
Wpływ zwiazków blokujacych receptory muskarynowe i blokujacych kanały wapniowe na reaktywność oskrzeli i parametry wentylacyjne u pacjentów z obturacyjnymi chorobami płuc.