Beef-heart mitochondrial F1-ATPase can use endogenous bound phosphate to synthesize ATP in dimethyl sulfoxide.
Beef-heart mitochondrial F1-ATPase contained 5 mol of inorganic phosphate bound per mol of F1, following pretreatment with ATP. A portion of the phosphate, bound most likely at a catalytic site, reacted in dimethylsulfoxide with endogenous adenine nucleotide to form ATP.
Beharry
S
S
Department of Biochemistry, University of British Columbia, Vancouver, Canada.
Bragg
P D
PD
D000255:Adenosine Triphosphate / Q000096:biosynthesis*; D000818:Animals; D002384:Catalysis; D002417:Cattle; D004121:Dimethyl Sulfoxide; D008929:Mitochondria, Heart / Q000187:drug effects / Q000201:enzymology*; D010085:Oxidative Phosphorylation; D010710:Phosphates / Q000378:metabolism*; D006180:Proton-Translocating ATPases / Q000378:metabolism*
D010710:Phosphates; D000255:Adenosine Triphosphate; D006180:Proton-Translocating ATPases; D004121:Dimethyl Sulfoxide