Linkage relationship between incontinentia pigmenti (IP2) and nine terminal X long arm markers.
Linkage data for familial incontinentia pigmenti (IP2) and nine X chromosomal markers are reported. Previously found linkage between IP2 and the DXS52 locus is confirmed with the maximum lod score of 6.19 at a recombination fraction of 0.03. Linkage is also established with loci DXS134, DXS15 and DXS33. Multipoint analysis allows us to localize the IP2 locus outside a block of seven linked markers of the Xq28 region.
Sefiani
A
A
Unité INSERM U. 12, Hôpital des Enfants-Malades, Paris, France.
M'rad
R
R
Simard
L
L
Vincent
A
A
Julier
C
C
Holvoet-Vermaut
L
L
Heuertz
S
S
Dahl
N
N
Stalder
J F
JF
Peter
M O
MO
D002874:Chromosome Mapping; D004262:DNA Restriction Enzymes; D005260:Female; D005804:Genes, Lethal; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D007184:Incontinentia Pigmenti / Q000235:genetics*; D008297:Male; D010375:Pedigree; D014960:X Chromosome
D005819:Genetic Markers; D004262:DNA Restriction Enzymes