title: [Acute severe pancreatitis. Analysis of mortality and morbidity].
abstract: Sixty-three patients with severe acute pancreatitis have been studied. Pancreatitis was associated with biliary tract disease in 23 patients (36.5%) and with alcoholism in 21 (33.3%). It occurred post-operatively in 9, and was associated with other conditions in 10. We evaluated the Ranson prognostic signs (RPS) with the appearance of complications. 36 patients (57.2%) had 3-4 RPS, 9 (30.2%) had 5-6 RPS and 8 (12.6%) had 7 or more RPS. Diagnostic laparotomy was performed in 11 patients (17.5%). 55 patients were operated one or more times due to failure of medical treatment and/or local and septic complications. The most frequent complications were pancreatic abscess (60.3%), sepsis (58.7%) and pulmonary insufficiency (52.4%). Renal failure occurred in 26 patients and 9 required dialysis. Of the patients with renal failure, 84.6% (22/26) had 4 or more RPS; 78.4% (29/37) of those with sepsis and 71.6% (27/38) of those with pancreatic abscess also had 4 or more RPS. The mean duration of hospitalization of survivors was 58 +/- 30 days. Overall mortality was 28.6%. We conclude that RPS are helpful to predict complications in patients with severe pancreatitis.
authors.affiliation: Servicio de Cirugía, Hospital Clínico P Universidad Católica de Chile, Santiago.
authors.forename: J
authors.initials: J
authors.lastname: Martínez
authors.forename: A
authors.initials: A
authors.lastname: Zúñiga
authors.forename: S
authors.initials: S
authors.lastname: Guzmán
authors.forename: O
authors.initials: O
authors.lastname: Llanos
authors.forename: A
authors.initials: A
authors.lastname: Rahmer
authors.forename: P
authors.initials: P
authors.lastname: Troncoso
authors.forename: M
authors.initials: M
authors.lastname: Escobar
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000437:Alcoholism / Q000150:complications; D002769:Cholelithiasis / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D010195:Pancreatitis / Q000209:etiology / Q000401:mortality* / Q000601:surgery; D011183:Postoperative Complications; D011379:Prognosis; D011446:Prospective Studies; D012189:Retrospective Studies
vernacular_title: Pancreatitis aguda grave: analisis de la mortalidad y morbilidad.