title: [Viral hepatitis and blood transfusion].
abstract: Our findings show that hepatitis B-virus was transmitted by blood from two hepatitis B-surface-antigen (HBsAg)-negative but hepatitis B-coreantibody (anti-HBc)-positive donors. Blood donors and recipients were also tested for antibodies against the recently identified hepatitis C-virus (HCV). We found that two anti-HCV-positive donors with no known history of clinical hepatitis were chronic, infective carriers of HCV. The prevalence of anti-HCV in our blood donor population was 0.47% and ALT and anti-HBc testing was of no help for tracing the anti-HCV positives. We recommend that, in addition to HBsAg screening at each donation, donors are tested for anti-HBc and anti-HCV once. Individuals with a history of parenteral virus hepatitis should not be accepted as blood donors.
authors.affiliation: Blodbank og immunologisk avdeling, Ullevål sykehus, Oslo.
authors.forename: J
authors.initials: J
authors.lastname: Larsen
authors.forename: G
authors.initials: G
authors.lastname: Hetland
authors.forename: K
authors.initials: K
authors.lastname: Skaug
authors.forename: A
authors.initials: A
authors.lastname: Maeland
mesh_terms: D001782:Blood Donors; D005260:Female; D016174:Hepacivirus / Q000276:immunology; D006508:Hepatitis Antibodies / Q000032:analysis; D006509:Hepatitis B / Q000635:transmission*; D006515:Hepatitis B virus / Q000276:immunology; D006526:Hepatitis C / Q000635:transmission*; D006525:Hepatitis, Viral, Human / Q000209:etiology*; D006801:Humans; D008297:Male; D065227:Transfusion Reaction
chemical_list: D006508:Hepatitis Antibodies
vernacular_title: Virushepatitt og blodtransfusjon.