title: [Psychophysiologic markers of arterial hypertension].
abstract: Many studies, concerning cardiovascular reactivity in hypertensives, show contrasting data. The aim of the present study was to check, also measuring extracardiovascular variables, a procedure able to identify a peculiar characteristic of the prehypertensive phase. We studied 47 normotensives, who referred high blood pressure values, but that we did not find in our visit. The cardioneurovascular assessment was evaluated, by means of a non invasive, beat to beat technique, measuring SBP, DBP, HR, muscular contraction and skin conductance level (EMG, SCL), peripheric temperature (PT), during a psychophysiologic session. This was composed by 4 stressors (mental arithmetic and Sacks test, acoustic and electric stimulations), 5 minutes each, preceded and followed by an observation period of 10 minutes. After 18 month follow-up, we could distinguish 26 hypertensives (H), and 21 subjects maintained normal blood pressure values (N). The obtained findings showed, with statistical significance, 1) the hyperresponsiveness of SCL and PT; 2) the failed recovery, with consequent hyperdysreactivity, of SCL and PT; 3) the presence of both these phenomena in the H., while SBP, DBP and HR responses did not result a discriminative tool. These data seem 1) to reinforce the hypothesis that a hypersympathetic phase can characterize the prehypertensive stages of essential hypertension and 2) to suggest the psychophysiological approach as a useful method to diagnose prehypertension.
authors.affiliation: Centro universitario studio dello stress, Università di Bari.
authors.forename: P
authors.initials: P
authors.lastname: Nazzaro
authors.forename: M
authors.initials: M
authors.lastname: Manzari
authors.forename: M
authors.initials: M
authors.lastname: Merlo
authors.forename: A
authors.initials: A
authors.lastname: Pirrelli
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D001831:Body Temperature; D004558:Electric Stimulation; D005260:Female; D005712:Galvanic Skin Response; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology* / Q000523:psychology; D008297:Male; D009129:Muscle Tonus; D009483:Neuropsychological Tests; D013315:Stress, Psychological / Q000150:complications / Q000503:physiopathology*; D013564:Sympathetic Nervous System / Q000503:physiopathology*
vernacular_title: Markers psicofisiologici di ipertensione arteriosa.