Chromosomal aberrations in the mildly mentally retarded.
Chromosome analyses were performed on 52 mildly mentally retarded adults and a control group representing the non-retarded population. Chromosomal aberrations were found in 19.2% of the mentally retarded and in 1.9% of the controls. The aberrations in the retarded group consisted of trisomy 21, fragile-X, sex-chromosome aberrations and balanced translocations. The index group included a man with a fragile site Xp22.1. The aberration in the control group consisted of a karyotype with an extra marker chromosome.
Göstason
R
R
Social Board of the Kopparberg County Council, Falun, Sweden.
Wahlström
J
J
Johannisson
T
T
Holmqvist
D
D
D002872:Chromosome Deletion; D003430:Cross-Sectional Studies; D004314:Down Syndrome / Q000453:epidemiology / Q000235:genetics; D005111:Extrachromosomal Inheritance / Q000235:genetics; D005600:Fragile X Syndrome / Q000453:epidemiology / Q000235:genetics; D005787:Gene Frequency / Q000235:genetics*; D006801:Humans; D015994:Incidence; D008607:Intellectual Disability / Q000453:epidemiology / Q000235:genetics*; D007621:Karyotyping; D009030:Mosaicism / Q000235:genetics; D012729:Sex Chromosome Aberrations / Q000453:epidemiology / Q000235:genetics*; D013548:Sweden / Q000453:epidemiology; D014960:X Chromosome