title: Cost-effectiveness of hepatitis B screening in a mental health institution.
abstract: In 1982, the Ohio Department of Health Screening established guidelines for hepatitis B screening and vaccination for intermediate mental health care facilities. The present study was developed to evaluate the cost-effectiveness of these guidelines. Data from an intermediate mental health care institution in Champaign/Urbana, Illinois, were used. The analysis considered the direct costs and benefits accrued over a 3-year period and a range of transmission rates. At a 3-year transmission rate of 0.030, the screening and vaccination policy cost $7300 per case of hepatitis B avoided (or $345,800 per hepatitis B fatality avoided). At a more likely 3-year transmission rate of 0.271, the screening and vaccination policy cost $300 per case of hepatitis B avoided (or $12,100 per hepatitis B fatality avoided). Either way, the active prevention policy compares very well with the amounts of money spent by the US Government on other life-saving programs. A general cost-effectiveness model is given that can be adapted for institution-specific analyses at other mental health care facilities.
authors.affiliation: Department of Family Practice, University of Illinois, Urbana/Champaign.
authors.forename: J
authors.initials: J
authors.lastname: Leonard
authors.forename: D R
authors.initials: DR
authors.lastname: Holtgrave
authors.forename: R P
authors.initials: RP
authors.lastname: Johnson
mesh_terms: D003362:Cost-Benefit Analysis / Q000706:statistics & numerical data; D005260:Female; D006509:Hepatitis B / Q000191:economics / Q000276:immunology / Q000517:prevention & control*; D006512:Hepatitis B Core Antigens / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D017325:Hepatitis B Vaccines; D006801:Humans; D007087:Illinois; D008607:Intellectual Disability; D008297:Male; D008403:Mass Screening / Q000191:economics*; D012112:Residential Facilities / Q000191:economics*; D014611:Vaccination; D014761:Viral Hepatitis Vaccines
chemical_list: D006512:Hepatitis B Core Antigens; D006514:Hepatitis B Surface Antigens; D017325:Hepatitis B Vaccines; D014761:Viral Hepatitis Vaccines