title: Sodium and potassium channels in epithelial cells from thymus glands and thymomas of myasthenia gravis patients.
abstract: In both normal and neoplastic epithelial cells from human thymus glands and thymomas, respectively, we found voltage-gated sodium and potassium channels that resemble the adult-type Na channel and the delayed outward rectifier K channel, respectively, of human skeletal muscle and mammalian nervous system. These voltage-gated ion channels might be part of a communication system between epithelial cells and other components of the microenvironment of the thymus.
authors.affiliation: Pathologisches Institut, Universität Würzburg, Federal Republic of Germany.
authors.forename: A
authors.initials: A
authors.lastname: Marx
authors.forename: J
authors.initials: J
authors.lastname: Siara
authors.forename: R
authors.initials: R
authors.lastname: Rüdel
mesh_terms: D004553:Electric Conductivity; D004848:Epithelium / Q000473:pathology; D006801:Humans; D015640:Ion Channel Gating; D009157:Myasthenia Gravis / Q000473:pathology*; D015221:Potassium Channels / Q000502:physiology*; D015222:Sodium Channels / Q000502:physiology*; D013945:Thymoma / Q000473:pathology; D013950:Thymus Gland / Q000473:pathology*; D013953:Thymus Neoplasms / Q000473:pathology; D014407:Tumor Cells, Cultured
chemical_list: D015221:Potassium Channels; D015222:Sodium Channels