Comparative fate of the tritiated trichothecene mycotoxin, T-2 toxin, in chickens and ducks.
A tritiated preparation of the trichothecene mycotoxin, T-2 toxin, was administered as a single oral dose to 21-day-old male broiler (Hubbard x Hubbard) chickens and White Pekin ducks. There were few significant differences between the two species in metabolism, tissue retention, and excretion of T-2 toxin and its metabolites. On the basis of the data obtained, the differences in toxicological sensitivity to T-2 toxin known to exist between these two species cannot likely be attributed to differences in the metabolism or elimination of T-2 toxin from the body.
Giroir
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LE
USDA, Food Animal Protection Research Laboratory, College Station, Texas 77845.
Ivie
G W
GW
Huff
W E
WE
D000818:Animals; D002645:Chickens / Q000378:metabolism*; D002855:Chromatography, Thin Layer; D004350:Drug Residues / Q000493:pharmacokinetics*; D004372:Ducks / Q000378:metabolism*; D005895:Gizzard, Avian / Q000378:metabolism; D008297:Male; D009132:Muscles / Q000378:metabolism; D013605:T-2 Toxin / Q000737:chemistry / Q000493:pharmacokinetics*; D014018:Tissue Distribution
D013605:T-2 Toxin