title: Anti-trichomonad IgA antibodies in trichomoniasis before and after treatment.
abstract: Anti-trichomonad IgA antibodies were estimated by enzyme-linked immunosorbent assay (ELISA) in serum and vaginal secretions of 25 symptomatic and 25 asymptomatic Trichomonas vaginalis positive patients before and after treatment and in 25 age-matched controls. Significantly higher levels of antitrichomonad IgA antibodies were found in T. vaginalis positive patients when compared to control subjects, especially in vaginal secretions. In addition, a significant decrease in these antibodies was observed after treatment, which was more pronounced in vaginal secretions. It seems that anti-trichomonad IgA antibodies in serum and more so in vaginal secretions are directly related to and specific to the presence of T. vaginalis in the urogenital tract.
authors.affiliation: Department of Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: P
authors.initials: P
authors.lastname: Sharma
authors.forename: N
authors.initials: N
authors.lastname: Malla
authors.forename: I
authors.initials: I
authors.lastname: Gupta
authors.forename: N K
authors.initials: NK
authors.lastname: Ganguly
authors.forename: R C
authors.initials: RC
authors.lastname: Mahajan
mesh_terms: D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D014247:Trichomonas Vaginitis / Q000188:drug therapy / Q000276:immunology*; D014246:Trichomonas vaginalis / Q000276:immunology*
chemical_list: D000913:Antibodies, Protozoan; D007070:Immunoglobulin A