[Transplacental passage of Wuchereria bancrofti microfilariae in newborns of microfilaremic mothers].
The occurrence of circulating Wuchereria bancrofti microfilariae was investigated in 304 pregnant women from the "Unidade Mista Pof. Barros Lima" and "Hospital das Clínicas/UFPE". The filtration technique was employed to detect microfilaraemia during pregnancy, and 13 women were found to be positive (4.2%). The investigation of microfilariae in the cord blood of their children was negative (6/13), and also in venous blood samples collected up to 72 hours after birth and with 6 months of life. Milk samples from these mothers also had no microfilariae. The authors suggest that the occurrence of placentary lesions may be a possible factor involved in the transplacental transfer of microfilariae, and that in utero exposure to microfilariae and/or filarial antigens may influence the response to a filarial infection acquired later, thus being important a clinical and laboratorial follow-up of children exposed previously to filarial antigens during early periods of human development.
Pires
M L
ML
Centro de Pesquisas Aggeu Magalhães (CPqAM), FIOCRUZ, Recife, Brasil.
Ferreira
R S
RS
Araújo
S
S
Albuquerque
R
R
Remigio Neto
J
J
Da Silva
A S
AS
Dreyer
G
G
D000293:Adolescent; D000328:Adult; D000818:Animals; D001938:Brazil; D004605:Elephantiasis, Filarial / Q000097:blood / Q000635:transmission*; D005260:Female; D005312:Fetal Blood / Q000469:parasitology*; D006801:Humans; D007231:Infant, Newborn; D010865:Pilot Projects; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic; D014958:Wuchereria bancrofti
Investigação sobre a passagem transplacentária de microfilárias de Wuchereria bancrofti em recém-nascidos de mães microfilarêmicas.