[Antibiotic prophylaxis with ceftazidime in pediatric surgery].
The authors report their experience with Ceftazidime in surgical prophylaxis in childhood. 50 patients have been treated, suffering from surgical diseases, with 100 mg/kg of Ceftazidime in 3 doses (1 before, 1 after 6 hrs and 1 after 12 hrs from surgery). No side effects were observed and in no case was it necessary to discontinue treatment. Both bacterial and clinical results indicate good tolerability and very rapid effectiveness of the drug. Complications were present in 3 cases (6%) (in 2 cases wound infiltration and in 1 case a Douglas abscess) but no modification in treatment was necessary. All complications were present in so-called "dirty surgery" with a relative percentage of 18.7, that is far below values reported in the literature for this kind of surgery.
Inserra
A
A
Istituto di Ricerca Scientifica, Divisione di Chirurgia Pediatrica, Ospedale del Bambin Gesù Roma.
Serventi
P
P
Ciprandi
G
G
Sommi
M
M
Silvano
A
A
Boglino
C
C
D000293:Adolescent; D000367:Age Factors; D002442:Ceftazidime / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D007223:Infant; D007239:Infections / Q000453:epidemiology; D007558:Italy / Q000453:epidemiology; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology; D011292:Premedication; D013530:Surgical Wound Infection / Q000453:epidemiology
D002442:Ceftazidime
Antibioticoprofilassi con ceftazidime in chirurgia pediatrica.