title: [Necessity to adopt and disseminate therapeutic schemes for the treatment of American tegumentary leishmaniasis in Paraná].
abstract: American cutaneous leishmaniasis has shown an endemic character in areas of North-North-west Paraná State, which were populated in 40's, where residual forests persist with intense modifications. The infection has been found mainly in males, but was found also in females and children and in many individuals of a same family. 513 cases of cutaneous leishmaniasis notified to SUCAM by clinical diagnosis were investigated. Treatment was begun with Glucantime at State Health Centers or at SUCAM. Of 513 treated patients 260 (50.67%) were considered clinically cured. The remaining 253 (49.33%) abandoned treatment. The quantity of Glucantime supplied to the patients varied from 10 vials to more than 200, with or without intervals during the treatment. Two hundred and seventeen (85.46%) patients among 260 received from 10 to 75 vials. The occurrence of leishmaniasis in 163 (31.75%) women and in 34 (6.62%) children, of both sexes, up to 10 years old, suggests domiciliary transmission. It's not known if the 253 (49.33%) individuals who abandoned the treatment recovered. This high number shows the necessity of better knowledge of the consequences that can occur due to incomplete treatment.
authors.affiliation: Fundação Universidade Estadual de Maringá, Paraná, Brasil.
authors.forename: U
authors.initials: U
authors.lastname: Teodoro
authors.forename: R P
authors.initials: RP
authors.lastname: Spinoza
authors.forename: V
authors.initials: V
authors.lastname: La Salvia Filho
authors.forename: A L
authors.initials: AL
authors.lastname: Guilherme
authors.forename: A P
authors.initials: AP
authors.lastname: Lima
authors.forename: G M
authors.initials: GM
authors.lastname: Junqueira
authors.forename: N M
authors.initials: NM
authors.lastname: Misuta
authors.forename: A
authors.initials: A
authors.lastname: Nerilo Sobrinho
authors.forename: E M
authors.initials: EM
authors.lastname: de Lima
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D016773:Leishmaniasis, Cutaneous / Q000188:drug therapy* / Q000453:epidemiology; D008297:Male; D008536:Meglumine / Q000627:therapeutic use*; D000077485:Meglumine Antimoniate; D008875:Middle Aged; D009942:Organometallic Compounds / Q000627:therapeutic use*; D012042:Registries
chemical_list: D009942:Organometallic Compounds; D008536:Meglumine; D000077485:Meglumine Antimoniate
vernacular_title: Da necessidade de se adotar e divulgar esquemas terapêuticos para tratamento de leishmaniose tegumentar no Paraná.