Kinetics of histone protein glycation.
The kinetics of glycation of histone proteins was studied. The glucose uptake of H1 linker histone reached saturation attained after an exponential course. H2-H4 core histone and total histone exhibited two-phase courses differing in time. With the uptake of glucose, the electromobility of the fractions changed. The kinetic results are explained in terms of interaction between proteins.
Lakatos
A
A
Department of Clinical Chemistry, University Medical School of Pécs, Hungary.
Jobst
K
K
D000818:Animals; D002417:Cattle; D005947:Glucose / Q000378:metabolism*; D006031:Glycosylation; D006657:Histones / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D007700:Kinetics; D010865:Pilot Projects
D006657:Histones; D005947:Glucose