Immunological treatment of cough occurring in dogs with dirofilariosis.
A persistent, spasmic and productive cough known as filarial cough often occurs in dogs with dirofilariosis, and has been considered to be the consequence of an allergic response to Dirofilaria immitis. Twenty-one dogs with filarial cough were subcutaneously injected with worm antigen (200 micrograms of protein concentration) extracted from adult D. immitis once a day for 5 days. These injections were effective for 17 (81%) of the dogs, resulting in a complete cure for 7 dogs and marked improvement for 10 dogs.
Hayasaki
M
M
Department of Internal Medicine and Parasitology, School of Veterinary Medicine, Tokyo University of Agriculture and Technology, Japan.
Harayama
A
A
Seki
H
H
Konno
K
K
Ohishi
I
I
D000818:Animals; D000909:Antibodies, Helminth / Q000097:blood; D000947:Antigens, Helminth / Q000627:therapeutic use*; D003371:Cough / Q000209:etiology / Q000628:therapy / Q000662:veterinary*; D004183:Dirofilaria immitis / Q000276:immunology*; D004184:Dirofilariasis / Q000150:complications / Q000662:veterinary*; D004283:Dog Diseases / Q000209:etiology / Q000628:therapy*; D004285:Dogs; D005260:Female; D005455:Fluorescent Antibody Technique; D006386:Hemagglutination Tests; D008297:Male
D000909:Antibodies, Helminth; D000947:Antigens, Helminth