Gene mapping by in situ hybridization.
Genome maps with a resolution of approximately 50kb can now be produced by applying the technique of two-color fluorescence in situ hybridization to chromatin targets in varying stages of condensation, such as metaphase chromosomes, interphase nuclei and sperm pronuclei.
Trask
B J
BJ
Biomedical Services Division, Lawrence Livermore National Laboratory, Livermore, California 94550.
D000818:Animals; D001345:Autoradiography / Q000379:methods; D002453:Cell Cycle; D002467:Cell Nucleus / Q000648:ultrastructure; D002843:Chromatin / Q000648:ultrastructure; D002874:Chromosome Mapping / Q000379:methods*; D002875:Chromosomes / Q000648:ultrastructure; D015342:DNA Probes; D005456:Fluorescent Dyes; D005819:Genetic Markers; D006801:Humans; D008297:Male; D008540:Meiosis; D008938:Mitosis; D009693:Nucleic Acid Hybridization; D010944:Plants; D013094:Spermatozoa / Q000648:ultrastructure
D002843:Chromatin; D015342:DNA Probes; D005456:Fluorescent Dyes; D005819:Genetic Markers