[The effect of plasmin on complement in human blood serum].
Plasma exhibited the dose-dependent inactivating effect on human blood serum hemolytic complement both in classic and alternative pathways. Negative correlation (r = -0.8) was found between the rate of complement inactivation and content of C3 component. Plasmin appears to hydrolyze mainly the C3 component of complement as a result of which hemolytic activity of complement is decreased.
Riumina
E V
EV
Galevskaia
L V
LV
Shcherbak
I G
IG
D001769:Blood; D003171:Complement Pathway, Classical; D003165:Complement System Proteins / Q000378:metabolism*; D005341:Fibrinolysin / Q000378:metabolism*; D006461:Hemolysis; D006801:Humans; D006868:Hydrolysis
D003165:Complement System Proteins; D005341:Fibrinolysin
Vliianie plazmina na komplement syvorotki krovi cheloveka.