title: Clinical-instrumental evaluation of the effects of mesoglycan sulphate in chronic vascular encephalopathy.
abstract: 15 patients with chronic cerebrovascular disease were studied using carotid Doppler and B-mode echography, transcranial Doppler, EEG and clinical evaluation before and 3 and 6 months after treatment with mesoglycan sulphate at doses of 96 mg/day per os. A subjective improvement was reported by 7 out of 15 patients while no significant variations in Doppler, TCD, echographic and EEG data were observed. During treatment no side effects or laboratory abnormalities were found.
authors.affiliation: Unit of Clinical Neurophysiology, Dpt. of Neurology, University of Fisa, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Orlandi
authors.forename: F
authors.initials: F
authors.lastname: Viapiano
authors.forename: R
authors.initials: R
authors.lastname: Massetani
authors.forename: M
authors.initials: M
authors.lastname: Ferrari
authors.forename: L
authors.initials: L
authors.lastname: Murri
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002561:Cerebrovascular Disorders / Q000188:drug therapy*; D002908:Chronic Disease; D005260:Female; D006025:Glycosaminoglycans / Q000627:therapeutic use*; D006801:Humans; D008297:Male
chemical_list: D006025:Glycosaminoglycans; C040617:mesoglycan