title: Nutrition and serum cholesterol levels among elderly men and women (Dutch Nutrition Surveillance System).
abstract: Associations of serum cholesterol with relevant dietary intake variables (assessed with the dietary history method) and body mass index were investigated in elderly men (n = 199) and women (n = 180) 65-79 years old. All subjects were apparently healthy, nondiabetic, and not on a dietary regimen. The associations were studied separately for men and women using linear regression analysis and all possible subsets regression analysis. Among men, body mass index (kg/m2) and intake of monounsaturated fat and of alcohol were positively and consistently associated with serum total cholesterol. Among women, intake of alcohol and of saturated fat were positively associated, and intake of polysaccharides was inversely associated with serum total cholesterol. The intake of monounsaturated fatty acids was highly (r greater than .60) positively correlated with the intake of total fat and saturated fatty acids, and inversely with carbohydrates. HDL-cholesterol was positively associated with alcohol intake (significant for men only), and inversely with body mass index (women). The results indicate that the effect of dietary factors on serum cholesterol levels is probably not age-limited. Elderly people may potentially benefit from weight reduction or control, moderate alcohol consumption, and avoidance of too much dietary fat. These suggestions are in fair accordance with general population-based guidelines for a healthy diet. However, as our study was cross-sectional, causation as well as the public health impact remains to be proven.
authors.affiliation: Department of Human Nutrition, TNO-CIVO, Toxicology and Nutrition Institute, Zeist, The Netherlands.
authors.forename: M R
authors.initials: MR
authors.lastname: Löwik
authors.forename: M
authors.initials: M
authors.lastname: Wedel
authors.forename: F J
authors.initials: FJ
authors.lastname: Kok
authors.forename: J
authors.initials: J
authors.lastname: Odink
authors.forename: S
authors.initials: S
authors.lastname: Westenbrink
authors.forename: J F
authors.initials: JF
authors.lastname: Meulmeester
mesh_terms: D000368:Aged; D000375:Aging / Q000097:blood*; D000428:Alcohol Drinking; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D004032:Diet; D004040:Dietary Carbohydrates / Q000032:analysis; D004041:Dietary Fats / Q000032:analysis; D004043:Dietary Fiber / Q000032:analysis; D002149:Energy Intake; D005260:Female; D006801:Humans; D008297:Male; D009426:Netherlands; D009747:Nutritional Physiological Phenomena; D011159:Population Surveillance; D012044:Regression Analysis; D012737:Sex Factors
chemical_list: D008076:Cholesterol, HDL; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004043:Dietary Fiber; D002784:Cholesterol