[Presymptomatic diagnosis in Huntington chorea families using the gene amplification technique].
The presymptomatic diagnosis of Huntington chorea (HC) by genic amplification (PCR: polymerase chain reaction) of a DNA G8 sequence containing a polymorphic HindIII site was tested in a particular HC genealogy. The advantage of this method are discussed.
Lucotte
G
G
Laboratoire d'Anthropologie Physique, Collège de France, Paris.
Berriche
S
S
Petit
M C
MC
Burckel
A
A
Turpin
J C
JC
D005784:Gene Amplification / Q000235:genetics; D006801:Humans; D006816:Huntington Disease / Q000175:diagnosis* / Q000235:genetics; D021141:Nucleic Acid Amplification Techniques; D010375:Pedigree
Diagnostic présymptomatique dans les familles de chorée de Huntington par utilisation de la technique d'amplification génique.