title: [Hexakis, (t-butylisonitryl/technetium, 99mTc-TBI), a cold-focal cardiac radiopharmaceutic agent and its distribution in the body].
abstract: The distribution of coldfocal cardiopharmacological substance 99mTc-TBI has been studied on a total of 14 dogs in relation to the healthy heart tissue. The quality heart scan resulted from the use of 99mTc-TBI. It may be performed 30 min after the administration of mentioned substance, when its blood activity is smaller than 10% activity of myocardium From the other organs, the myocardium scan may be influenced negatively with only liver which achieves 200% activity of left heart ventricle what is evidently consequential in worse imaging of "lower" ischemic lesions. These results justify us to conclude that the 99mTc-TBI is a substance suitable for scintigraphical imaging of myocardium.
authors.forename: L
authors.initials: L
authors.lastname: Hadas
authors.forename: A
authors.initials: A
authors.lastname: Vosecková
authors.forename: F
authors.initials: F
authors.lastname: Duska
authors.forename: J
authors.initials: J
authors.lastname: Vizda
authors.forename: P
authors.initials: P
authors.lastname: Kafka
authors.forename: E
authors.initials: E
authors.lastname: Urbanová
mesh_terms: D000818:Animals; D004285:Dogs; D006321:Heart / Q000000981:diagnostic imaging*; D009570:Nitriles; D015609:Organotechnetium Compounds / Q000493:pharmacokinetics*; D011877:Radionuclide Imaging; D014018:Tissue Distribution
chemical_list: D009570:Nitriles; D015609:Organotechnetium Compounds; C043714:technetium Tc 99m hexakis(tert-butylisonitrile)
vernacular_title: Studenoloziskové srdecní radiofarmakon Hexakis (t-Butylisonitryl/Technetium (99mTc-TBI) a jeho distribuce v organismu.