[Pharmacology of atriopeptin in the adult rat: power spectra of the fluctuations in heart rate].
The persistence of the cardiac beat-to-beat control is studied in the anesthetized and the pithed adult rat by means of spectral analysis. The data show that atriopeptin affects the amplitude of the heart rate low frequency fluctuations, significantly increasing the spectral patterns both in the anesthetized and the pithed rat. The atriopeptin enhancement of the low frequency range in heart rate fluctuations provides further insight into the hypothesis that beat to beat variability in hemodynamic parameters reflects a compensatory response in the short term cardiovascular control.
Tonnini
C
C
I.M.O.-Centro Interuniversitario Interdipartimentale, Interazioni Biofisiche e Biochimiche Molecole e Organismi.
Bernardi
M
M
Montecchiani
G
G
Rossini
L
L
D000758:Anesthesia; D000818:Animals; D009320:Atrial Natriuretic Factor / Q000494:pharmacology*; D003655:Decerebrate State / Q000503:physiopathology*; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D008297:Male; D010446:Peptide Fragments / Q000494:pharmacology*; D051381:Rats
D010446:Peptide Fragments; D009320:Atrial Natriuretic Factor; C043970:atrial natriuretic factor 26, rat; C044120:atrial natriuretic factor prohormone (8-33)
Farmacologia dell'atriopeptina nel ratto adulto: spettri di potenza delle fluttuazioni della frequenza cardiaca.