[Blood group P1 and its relation to renal cicatrix in patients with urinary infection].
Possible relationships between renal scars and P blood group have been recently emphasized. Urinary tract infections, an important factor in the production of renal scar, are mainly caused by specific types of E. coli, which has the ability to adhere through fimbriae, to receptors of the urinary tract epithelium that are structurally related to antigens detected in people with blood group P1. We looked for P1 sub-group in 30 children with vesicoureteral reflux and renal scar and 30 patients with equivalent degrees of reflux but without evidence of renal scar. Sex and age were unmatched. The frequency of P1 blood sub-group was similar in both kinds of patients (56.7% vs. 66.7, n.s.) so we could not demonstrate that P1 sub-group can be a useful indirect risk marker for renal scar formation.
Saieh
C
C
Hospital Luis Calvo Mackenna.
Olguín
H
H
Macho
L
L
Herrera
C
C
D001422:Bacterial Adhesion; D002648:Child; D002921:Cicatrix / Q000097:blood* / Q000209:etiology; D004927:Escherichia coli Infections / Q000150:complications; D006801:Humans; D007674:Kidney Diseases / Q000097:blood* / Q000209:etiology; D010127:P Blood-Group System; D012307:Risk Factors; D014552:Urinary Tract Infections / Q000097:blood*; D014718:Vesico-Ureteral Reflux / Q000097:blood*
D010127:P Blood-Group System
Grupo sanguíneo P1 y su reláción con cicatriz renal en pacientes con infección urinaria.