[Time-lapse microcinematographical analysis of the biological characteristics of a macrophage-like cell line--MMC-1].
By using time-lapse microcinematography, we recorded and conducted an analysis of the macrophage-like cell line MMC-1, including observations of the spreading, polarity, contact inhibition and mitosis common to cultured cells as well as the properties of phagocytosis and rosette formation unique to macrophage. We also found an MMC-1 cell which, after feeding, still stretched its finger-like filopodia towards surrounding red blood cells. The filopodia extended as red blood cells moved towards them. At the point of contact, red blood cell fragments were seen moving towards the cell body along the filopodia; a kind of cytolysis was progressing.
Wang
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R
Institute of Basic Medical Sciences, Beijing.
D000818:Animals; D002460:Cell Line; D008264:Macrophages / Q000166:cytology* / Q000502:physiology; D051379:Mice; D008938:Mitosis; D009040:Motion Pictures; D010587:Phagocytosis; D012397:Rosette Formation