Antibody to serotype 8 rotavirus in Ecuadorian and German children.
Only 2 out of 71 German patients infected with rotavirus (3%) and 8 out of 147 German control patients (5%) showed serum antibody to the new serotype 8 rotavirus. Such antibody was detected in the sera of 232 of 870 Ecuadorian children (27%). Twelve Ecuadorian sera showed neutralizing activity only against serotype 8 and not to the other serotypes (1-4) tested, indicating that human serotype 8 rotavirus circulates in South America.
Brüssow
H
H
Nestlé Research Centre, Nestec Ltd, Lausanne, Switzerland.
Sidoti
J
J
D000208:Acute Disease; D000367:Age Factors; D000914:Antibodies, Viral / Q000097:blood*; D002675:Child, Preschool; D004484:Ecuador / Q000453:epidemiology; D005759:Gastroenteritis / Q000453:epidemiology*; D005860:Germany, West / Q000453:epidemiology; D006801:Humans; D007223:Infant; D009500:Neutralization Tests; D015995:Prevalence; D012401:Rotavirus / Q000276:immunology*; D012400:Rotavirus Infections / Q000453:epidemiology*
D000914:Antibodies, Viral