[Comparison of parasitology of the central vein of the adrenal gland and the other tissues in chronic chagas disease].
By morphological and morphometric analyses of serial sections the occurrence of T. cruzi nests in the central vein and in the parenchyma of adrenal glands, in the left ventricular wall and in the inferior vena cava wall in chronic Chagasic patients was studied. Of 36 cases 50% showed parasites in the adrenal central vein wall (total 29 nests), 3.1% showed parasites in the vena caval wall (only I nest) and 16.8% we found parasites in the myocardiocytes (total 23 nests). The density of parasites measured in the nests for each 100mm2 of the tissue examined, was 0.585 for the adrenal vein, 0.001 for the vena cava and 0.01 for the myocardium. No nest was found in 269103.1mm2 of adrenal parenchyma. Although the central vein area examined was smaller, it showed the largest frequency of T. cruzi nests. Since a basic difference between these tissues is the great quantity of corticoids in the blood of the adrenal central vein, this prevalence may be because of this hormonal ambient, which with its immunosuppressor and anti-inflammatory effects could help T. cruzi survival.
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Disciplina de Patologia Geral, Faculdade de Medicina do Triângulo Mineiro, Uberaba, MG.
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D000311:Adrenal Glands / Q000098:blood supply* / Q000469:parasitology*; D000328:Adult; D000368:Aged; D014355:Chagas Disease / Q000469:parasitology*; D002908:Chronic Disease; D005260:Female; D006321:Heart / Q000469:parasitology; D006801:Humans; D008297:Male; D008875:Middle Aged; D014680:Veins / Q000469:parasitology; D014682:Vena Cava, Inferior / Q000469:parasitology
Comparação do parasitismo da veia central da supra-renal com o de outros tecidos em chagásicos crônicos.