title: [Humoral response in health service personnel after administration of hepatitis B vaccine Gen-H-B-Vax].
abstract: Within the group of 260 members of medical staff, the presence of the HBV markers was found in 87 persons (33.5%). Vaccination, which was of a voluntary character, was initiated in the group of 75 persons according to the pattern of 0, 1, 6 months with the use of vaccine GenH-B-Vax (Merck Sharp Dohme-Chibret A. G.) was completed in 62 persons. Humoral response was investigated with quantitative measurement of anti-HBs 30 days after each doses of the vaccine. After three doses of vaccine a protective level of anti-HBs (greater than or equal to 10 IU/l) have been obtained in 90.3% of vaccinated. Humoral response was higher in the group of younger (below 35 years of life) employees. Investigated vaccine was highly immunogenic and was well tolerated.
authors.affiliation: Klinika Chorób Zakaźnych A. M. im. K. Marcinkowskiego w Poznaniu.
authors.forename: J
authors.initials: J
authors.lastname: Juszczyk
authors.forename: H
authors.initials: H
authors.lastname: Rokossowski
authors.forename: M
authors.initials: M
authors.lastname: Krajewska
authors.forename: A
authors.initials: A
authors.lastname: Piatek
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D005260:Female; D006509:Hepatitis B / Q000276:immunology / Q000517:prevention & control*; D006510:Hepatitis B Antibodies / Q000032:analysis / Q000096:biosynthesis / Q000276:immunology*; D017325:Hepatitis B Vaccines; D006515:Hepatitis B virus / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009426:Netherlands; D009784:Occupational Diseases / Q000276:immunology / Q000517:prevention & control*; D010564:Personnel, Hospital; D011044:Poland; D012737:Sex Factors; D014761:Viral Hepatitis Vaccines / Q000008:administration & dosage / Q000276:immunology*
chemical_list: D006510:Hepatitis B Antibodies; D017325:Hepatitis B Vaccines; D014761:Viral Hepatitis Vaccines
vernacular_title: Odpowiedź humoralna u pracowników słuzby zdrowia po szczepionce Gen-H-B-Vax przeciwsko wirusowemu zapaleniu watroby typu B.