title: Retrograde labelling of serotonergic projections onto the neuroendocrine bag cells of Aplysia.
abstract: Injection of rhodamine-conjugated latex microspheres into the right bag cell cluster of Aplysia brasiliana yielded retrograde labelling of a small number of cells in the cerebral and abdominal ganglia. Subsequent staining for serotonin immunoreactivity demonstrated consistent double-labelling in specific cerebral and abdominal ganglion serotonergic cells. The double-labelled populations were also stained in vivo by prior treatment with 5,7-dihydroxytryptamine. These retrogradely labelled serotonergic neurons may represent sources of inhibitory input to the neuroendocrine bag cells.
authors.affiliation: Marine Biomedical Institute, University of Texas Medical Branch, Galveston.
authors.forename: D R
authors.initials: DR
authors.lastname: McPherson
authors.forename: J E
authors.initials: JE
authors.lastname: Blankenship
mesh_terms: D000005:Abdomen / Q000294:innervation*; D000818:Animals; D001048:Aplysia / Q000502:physiology*; D005724:Ganglia / Q000166:cytology / Q000378:metabolism / Q000502:physiology*; D007840:Latex; D008863:Microspheres; D009490:Neurosecretory Systems / Q000166:cytology / Q000378:metabolism / Q000502:physiology*; D012235:Rhodamines; D012701:Serotonin / Q000378:metabolism / Q000502:physiology*; D009435:Synaptic Transmission
chemical_list: D007840:Latex; D012235:Rhodamines; D012701:Serotonin