title: Differentiation and the establishment of cell type during sporulation in Bacillus subtilis.
abstract: Differentiation in Bacillus subtilis involves the formation of specialized cell types called the mother cell and the forespore. These differ from each other and from their parent in developmental fate. Establishment of the two cell types and their subsequent differentiation is governed by the compartmentalized action of six developmental transcription factors.
authors.affiliation: Department of Cellular and Developmental Biology, Harvard University, Cambridge, Massachusetts 02138.
authors.forename: P
authors.initials: P
authors.lastname: Margolis
authors.forename: A
authors.initials: A
authors.lastname: Driks
authors.forename: R
authors.initials: R
authors.lastname: Losick
mesh_terms: D001412:Bacillus subtilis / Q000166:cytology / Q000235:genetics / Q000502:physiology*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D002451:Cell Compartmentation; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial; D008954:Models, Biological; D009024:Morphogenesis / Q000235:genetics; D012808:Sigma Factor / Q000235:genetics / Q000378:metabolism*; D013171:Spores, Bacterial; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
chemical_list: D001426:Bacterial Proteins; D012808:Sigma Factor; D014157:Transcription Factors