title: Adhesion formation after laparoscopic surgery in tubal pregnancy: a randomized trial versus laparotomy.
abstract: OBJECTIVE
  Women with ectopic pregnancy (EP) who have been operated on by laparoscopy are thought to have improved subsequent fertility, probably because of less adhesion formation. We aimed to evaluate the adhesion formation after laparoscopy as compared with laparotomy in a randomized trial.
  
  
  METHODS
  One hundred five patients with tubal pregnancy were stratified with regard to age and risk factors and randomized to surgery by laparoscopy or laparotomy. To evaluate adhesion formation and tubal status, 73 patients with strong desire of pregnancy underwent a second-look laparoscopy. The adhesion status at the ipsilateral and contralateral side at primary surgery was compared with the status at second-look laparoscopy.
  
  
  RESULTS
  Patients operated on by laparotomy developed significantly more adhesions at the operated side than patients operated on by laparoscopy (P less than 0.001). Substantially more patients in the laparotomy group underwent adhesiolysis at second-look laparoscopy than did patients in the laparoscopy group. Tubal patency did not differ between the groups.
  
  
  CONCLUSIONS
  Laparoscopic treatment of EP results in less impairment of the pelvic status compared with conventional conservative surgery.
authors.affiliation: Department of Obstetrics and Gynecology, University of Göteborg, Sweden.
authors.forename: P
authors.initials: P
authors.lastname: Lundorff
authors.forename: M
authors.initials: M
authors.lastname: Hahlin
authors.forename: B
authors.initials: B
authors.lastname: Källfelt
authors.forename: J
authors.initials: J
authors.lastname: Thorburn
authors.forename: B
authors.initials: B
authors.lastname: Lindblom
mesh_terms: D005187:Fallopian Tubes / Q000473:pathology / Q000503:physiopathology; D005260:Female; D005298:Fertility; D006801:Humans; D010535:Laparoscopy; D007813:Laparotomy; D011183:Postoperative Complications; D011247:Pregnancy; D011274:Pregnancy, Tubal / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D011446:Prospective Studies; D000267:Tissue Adhesions / Q000209:etiology* / Q000517:prevention & control