Re-analysis of the time factor in local control by radiotherapy of T3T4 squamous cell carcinoma of the larynx.
The use of logistic regression for the analysis of local control data is illustrated via a re-analysis of previously published data. A larger effect of overall time is found than in the original publication. In addition, the original analysis of 50 percent effective dose (ED50) is found to have obscured the relationship between local control and overall time for some doses.
Lindstrom
M J
MJ
Biostatistics Center, University of Wisconsin-Madison 53706.
Fowler
J F
JF
D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000532:radiotherapy*; D016015:Logistic Models; D015201:Meta-Analysis as Topic; D009364:Neoplasm Recurrence, Local; D012044:Regression Analysis; D013997:Time Factors