Adjuvant systemic therapy of stage I and II breast cancer.
The value of adjuvant systemic therapy has been clearly demonstrated in both node-positive and node-negative patients. However, there are many women with favorable prognoses whose breast cancer recurs. It has been possible only recently to identify subsets of patients who are at definite risk for recurrence. Advances both in selection and treatment of patients with early-stage breast cancer are being made as critical research questions are delineated and examined in prospective randomized trials.
Goodman
M
M
Section of Medical Oncology, Rush Presbyterian St. Luke's Medical Center, Chicago, IL.
D001943:Breast Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000523:psychology; D017024:Chemotherapy, Adjuvant / Q000379:methods / Q000592:standards*; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D015201:Meta-Analysis as Topic; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D011788:Quality of Life; D012106:Research; D015996:Survival Rate