The gene for human neurone specific ubiquitin C-terminal hydrolase (UCHL1, PGP9.5) maps to chromosome 4p14.
Ubiquitin carboxy terminal hydrolase 1, UCHL1, is a neurone-specific protein involved in the ubiquitin-mediated proteolytic pathway. The gene for human UCHL1 has been mapped to chromosome 4 using the polymerase chain reaction to amplify specifically the human UCHL1 sequences in rodent/human somatic cell hybrid DNA. A regional assignment of this locus to 4p14 has been made by in situ hybridization to metaphase chromosomes using both tritium and fluorescently labelled probes.
Edwards
Y H
YH
M.R.C. Human Biochemical Genetics Unit, Galton Laboratory, London.
Fox
M F
MF
Povey
S
S
Hinks
L J
LJ
Thompson
R J
RJ
Day
I N
IN
D001483:Base Sequence; D002871:Chromosome Banding; D002894:Chromosomes, Human, Pair 4; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D013869:Thiolester Hydrolases / Q000235:genetics*; D043222:Ubiquitin Thiolesterase
D013869:Thiolester Hydrolases; D043222:Ubiquitin Thiolesterase