Morphological study of the effect of abdominal compression on acute intestinal radiation syndrome. I. Local irradiation with 14 Gy.
The effect of abdominal compression on acute intestinal radiation syndrome in rats was studied morphologically using light microscopic and histochemical methods. It was confirmed that the method of abdominal compression introduced by Svoboda et al. does not induce either acute or later changes (until 11 months) of the structure of abdominal cavity organs. The structure of intestinal mucosa of rats exposed to local irradiation of the abdomen with 14 Gy of gamma radiation from a Co60 source with or without abdominal compression was quite different with respect to acute changes. Ischemia of the intestine wall protects stem cells of intestine epithelium and subsequently allows a rapid and pronounced regeneration of radiation injury.
Kamarád
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V
Institute of Histology and Embryology, Medical Faculty, Palacký University, Olomouc, Czechoslovakia.
Cernochová
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D
Svoboda
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V
D000005:Abdomen; D000135:Acid Phosphatase / Q000378:metabolism / Q000528:radiation effects; D000818:Animals; D003106:Colon / Q000473:pathology* / Q000528:radiation effects; D004798:Enzymes / Q000032:analysis; D005260:Female; D007082:Ileum / Q000473:pathology* / Q000528:radiation effects; D007410:Intestinal Diseases / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology; D007413:Intestinal Mucosa / Q000201:enzymology / Q000473:pathology* / Q000528:radiation effects; D007583:Jejunum / Q000473:pathology* / Q000528:radiation effects; D008938:Mitosis; D011312:Pressure; D011833:Radiation Injuries, Experimental / Q000473:pathology* / Q000503:physiopathology; D051381:Rats
D004798:Enzymes; D000135:Acid Phosphatase