title: [Sodium reabsorption and the aldosterone receptors in the cells of the kidney tubules in a dynamic disorder of the trophic function of the nervous system].
abstract: The results are presented of investigations on determining the functional state of mineralocorticoid receptor apparatus in rat kidney at diverse stages of the reflex renal dystrophy per se and that against the background of renal denervation along with propranolol injections produced at different terms following the disturbance of nervous system trophic function. It was shown that simultaneous blockade of neuroconductory and humoral pathways of pathological stimulus transmission from central end of cut ischiatic nerve to the kidney prevents the development of trophic disturbances in the organ as tested by the state of mineralocorticoid receptors, to a more extent than the blockade of neuroconductory pathway only. The activity of molecular structures which determine the mineralocorticoid reception in cells of renal tubules seems to be controlled both by central neuroconductory and humoral mechanisms.
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Akimov
authors.forename: A A
authors.initials: AA
authors.lastname: Rodionov
authors.forename: A I
authors.initials: AI
authors.lastname: Grishchenko
authors.forename: Ia I
authors.initials: IaI
authors.lastname: Azhipa
mesh_terms: D000042:Absorption; D000315:Adrenalectomy; D000450:Aldosterone / Q000502:physiology*; D000818:Animals; D001693:Biological Transport, Active; D003714:Denervation; D004195:Disease Models, Animal; D007668:Kidney / Q000294:innervation*; D007674:Kidney Diseases / Q000503:physiopathology*; D007684:Kidney Tubules / Q000503:physiopathology*; D008297:Male; D011433:Propranolol; D051381:Rats; D011965:Receptors, Glucocorticoid / Q000502:physiology*; D018161:Receptors, Mineralocorticoid; D012021:Reflex, Abnormal / Q000502:physiology*; D012964:Sodium / Q000378:metabolism*
chemical_list: D011965:Receptors, Glucocorticoid; D018161:Receptors, Mineralocorticoid; D000450:Aldosterone; D012964:Sodium; D011433:Propranolol
vernacular_title: Reabsorbtsiia natriia i retseptory al'dosterona v kletkakh kanal'tsev pochek v dinamike narusheniia troficheskoĭ funktsii nervnoĭ sistemy.