Large-cell anaplastic (Ki-1-positive) lymphoma complicated by disseminated intravascular coagulation.
Large-cell anaplastic lymphoma (Ki-1-positive lymphoma) was first described as a type of large-cell lymphoma that has morphologic, enzymatic, and immunologic similarities to malignant histiocytosis. To date, an association between Ki-1-positive lymphoma and disseminated intravascular coagulation has not been described, but cases of malignant histiocytosis with disseminated intravascular coagulation have been reported. We report a case of anaplastic, Ki-1-positive, large-cell lymphoma complicated by clinical and laboratory evidence of disseminated intravascular coagulation with histologic evidence of vascular invasion and fibrin thrombi.
Arber
D
D
Scott and White Clinic, Temple, TX 76508.
Bilbao
J
J
Bassion
S
S
D015703:Antigens, CD / Q000032:analysis*; D000943:Antigens, Differentiation / Q000032:analysis*; D000951:Antigens, Neoplasm / Q000032:analysis*; D004211:Disseminated Intravascular Coagulation / Q000209:etiology*; D005260:Female; D015329:Gene Rearrangement, T-Lymphocyte; D006801:Humans; D017730:Ki-1 Antigen; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000276:immunology / Q000473:pathology; D008875:Middle Aged; D010641:Phenotype
D015703:Antigens, CD; D000943:Antigens, Differentiation; D000951:Antigens, Neoplasm; D017730:Ki-1 Antigen