A study of bleeding patterns with two injectable contraceptives given postpartum and the effect of two non-hormonal treatments.
349 women were given Depo-Provera and 304 were given Nur-Isterate immediately after delivery. No significant difference in duration or amount of bleeding was found between the two injectables over 6 months. Although the incidence and duration of bleeding were greater when injectables were used postpartum than when used electively, they were not excessive. This option should therefore not be withheld. Treatment with anti-inflammatory and anti-fibrinolytic agents were not effective in controlling bleeding.
Sapire
K E
KE
Department of Obstetrics and Gynecology, University of Cape Town Medical School, Observatory, South Africa.
D003271:Contraceptive Agents, Female / Q000008:administration & dosage / Q000009:adverse effects; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007267:Injections; D008525:Medroxyprogesterone / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D017258:Medroxyprogesterone Acetate; D009288:Naproxen / Q000494:pharmacology; D009640:Norethindrone / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D049590:Postpartum Period; D011247:Pregnancy; D014148:Tranexamic Acid / Q000494:pharmacology; D014592:Uterine Hemorrhage / Q000188:drug therapy / Q000209:etiology*
D003271:Contraceptive Agents, Female; D009288:Naproxen; D014148:Tranexamic Acid; D017258:Medroxyprogesterone Acetate; D008525:Medroxyprogesterone; C024319:norethindrone enanthate; D009640:Norethindrone