title: [Arterial stenosis in the renal graft. Spontaneous evolution in 40 cases].
abstract: From January 1976 to June 1989, 138 renal artery stenoses (RAS) occurred in a population of 1,200 renal transplantations in a single center (11.5 percent). An interventional procedure was performed in 89 patients: surgery in 39 and transluminal angioplasty in 50. Six other patients were excluded from the study because of complications and RAS spontaneously disappeared in 3 patients. Finally, 40 patients were treated medically with a mean follow-up of 57.6 months (range 12 to 116 months). In this group, the actuarial graft survival rate did not significantly differ from that of the 2 other groups. One patient only lost his graft from renal artery thrombosis. The mean serum creatinine level at the time of RAS diagnosis (140 +/- 8.6 mumol/l) was not significantly different from the mean serum creatinine level at the last follow-up (146 +/- 14.6 mumol/l). The degree of hypertension, graded on the number of anti-hypertensive drugs, was not different at the time of diagnosis and at the end of follow-up. In conclusion, in our experience, the spontaneous course of RAS does not result in an increased rate of graft failure or impaired long-term renal function.
authors.affiliation: Service de Néphrologie et d'Urologie, Hôpital de Bicêtre, Le Kremlin.
authors.forename: A
authors.initials: A
authors.lastname: Deglise-Favre
authors.forename: C
authors.initials: C
authors.lastname: Hiesse
authors.forename: O
authors.initials: O
authors.lastname: Lantz
authors.forename: M
authors.initials: M
authors.lastname: Moukarzel
authors.forename: H
authors.initials: H
authors.lastname: Bensadoun
authors.forename: G
authors.initials: G
authors.lastname: Benoît
authors.forename: B
authors.initials: B
authors.lastname: Charpentier
authors.forename: D
authors.initials: D
authors.lastname: Fries
mesh_terms: D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000209:etiology; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012075:Remission, Spontaneous; D012078:Renal Artery Obstruction / Q000150:complications / Q000401:mortality*; D013997:Time Factors
chemical_list: D000959:Antihypertensive Agents
vernacular_title: Sténoses de l'artère du rein greffé. Evolution spontanée de 40 cas.