IgM-associated primary diffuse mesangial proliferative glomerulonephritis: natural history and prognostic indicators.
Fifty-four adults with primary mesangial proliferative glomerulonephritis and IgM deposition were observed for a minimum of three years or until end-stage renal failure. The actuarial renal survival was 80 per cent at 5 years and 64 per cent at 10 years; multivariate analysis identified microscopic haematuria, extent of mesangial proliferation and global glomerular sclerosis as independent prognostic indicators.
O'Donoghue
D J
DJ
Renal Unit, Manchester Royal Infirmary.
Lawler
W
W
Hunt
L P
LP
Acheson
E J
EJ
Mallick
N P
NP
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D005921:Glomerulonephritis / Q000276:immunology* / Q000401:mortality / Q000473:pathology; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology*; D007678:Kidney Glomerulus / Q000276:immunology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use; D011379:Prognosis; D012008:Recurrence
D007075:Immunoglobulin M; D011239:Prednisolone