title: [Clinical trials in dermatology. Evaluation of the tolerability and efficacy of a topical anti-acne].
abstract: Acne is a frequent dermatologic disease of the teenagers. Methodology of antiacne preparations clinical trials has evolved recently, leading to better comprehension of acne treatment on acne lesions. The main rules for good clinical evaluation of acne treatments are: an objective counting of each individual lesions on a defined area (face, back), a global acne assessment, a therapy duration from 1 to 3 months or more, a skin safety evaluation for erythema, desquamation, dryness, itching, burning and oiliness with a 0 to 3 scoring system.
authors.affiliation: Centre de Pharmacologie Clinique Appliquée à la Dermatologie, (C.P.C.A.D.), Hôpital Pasteur, Nice.
authors.forename: M
authors.initials: M
authors.lastname: Verschoore
authors.forename: M
authors.initials: M
authors.lastname: Poncet
authors.forename: H
authors.initials: H
authors.lastname: Schaefer
authors.forename: J
authors.initials: J
authors.lastname: Revuz
authors.forename: Y
authors.initials: Y
authors.lastname: De Prost
authors.forename: J C
authors.initials: JC
authors.lastname: Guillaume
authors.forename: J P
authors.initials: JP
authors.lastname: Ortonne
authors.forename: J
authors.initials: J
authors.lastname: Czernielewski
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy*; D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic / Q000379:methods*; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004341:Drug Evaluation / Q000379:methods; D006801:Humans
chemical_list: D003879:Dermatologic Agents
vernacular_title: Les essais cliniques en dermatologie. Evaluation de la tolérance et de l'efficacité d'un antiacnéique topique.