[Infections after massive bone allografts in surgery of bone tumors of the limbs. Incidence, contributing factors, therapeutic problems].
This study was carried out on a sample of 115 patients receiving massive allografts that were sterilized by irradiation and implanted after tumor resection, and having a remission period of 2-5 years. Among the 11 post-operative infections that occurred, 9 arose early and 2 arose late. The risk of infection was augmented when reconstruction by allograft followed tumor surgery requiring adjuvant chemotherapy and/or radiation treatments. Treatment of these allograft infections was difficult due to the presence of multiple bacteria as well as the general circumstances surrounding the infection (immunosuppressed patients under chemotherapy): 5 of the 11 patients required amputation secondary to infection.
Hernigou
P
P
Service de Chirurgie Orthopédique, Hôpital Henri Mondor, Créteil.
Delepine
G
G
Goutallier
D
D
D001859:Bone Neoplasms / Q000601:surgery*; D016025:Bone Transplantation / Q000009:adverse effects*; D005121:Extremities; D005500:Follow-Up Studies; D006801:Humans; D015831:Osteochondroma / Q000601:surgery; D012516:Osteosarcoma / Q000601:surgery; D012307:Risk Factors; D012512:Sarcoma, Ewing / Q000601:surgery; D013530:Surgical Wound Infection / Q000209:etiology* / Q000628:therapy; D013997:Time Factors
Infections après allogreffes osseuses massives dans la chirurgie des tumeurs osseuses des membres. Fréquence, facteurs favorisants, problèmes thérapeutiques.