title: Planned reoperations and open management in critical intra-abdominal infections: prospective experience in 52 cases.
abstract: Open management and "planned relaparotomies" in the treatment of critical abdominal infections have recently generated interest and hope. Most studies which examine the value of these therapeutic modalities are retrospective and include poorly stratified groups of patients. Since 1985, we have consistently applied these aggressive methods of treatment in all patients presenting with intra-abdominal infections belonging to the following groups: I) diffuse postoperative peritonitis (29 cases); II) diffuse fecal peritonitis (14 cases); and III) infected pancreatic necrosis (9 cases). The overall mortality rate was 44%; it was 55%, 14% and 56%, respectively, in the 3 groups. The abdomen was closed between reoperations in 21 patients who required an average of 1.7 relaparotomies; the mortality in this group was 24%. Thirty-one patients, who required an average of 3.8 relaparotomies, were managed with the open method resulting in a mortality of 58%. Multiple organ failure was the cause of death in 87% of the patients. We conclude that "planned relaparotomies" may have been beneficial in group II. The value of open management in patients belonging to groups I and III remains unproven. The mechanical-surgical answers to severe forms of peritonitis may have reached their limit.
authors.affiliation: Department of Surgery, University of the Witwatersrand, Johannesburg, South Africa.
authors.forename: M
authors.initials: M
authors.lastname: Schein
mesh_terms: D000009:Abdominal Muscles / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007239:Infections / Q000175:diagnosis / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010195:Pancreatitis / Q000175:diagnosis / Q000601:surgery*; D010538:Peritonitis / Q000175:diagnosis / Q000601:surgery*; D011446:Prospective Studies; D012086:Reoperation