Plasma-sprayed coatings of tetracalciumphosphate, hydroxyl-apatite, and alpha-TCP on titanium alloy: an interface study.
In order to study the interaction of calcium phosphate coatings with bone tissue, coated titanium cylinders with a standard size were implanted in dog femora. Coatings were made by plasma spraying powders of hydroxylapatite, beta-whitlockite, and tetracalciumphosphate particles. The plasma spraying process turns beta-whitlockite into alpha-TCP. Bone bonding and bone formation were evaluated by mechanical push-out tests and histological observations. Hydroxylapatite and tetracalciumphosphate coatings show an interface strength after 3 months of implantation of 34.3 +/- 6.5 MPa and 26.8 +/- 3.9 MPa, respectively, while alpha-TCP and blanco titanium lead to an interface strength of 10.0 +/- 3.5 MPa and 9.7 +/- 1.3 MPa, respectively. Histological examinations revealed that hydroxylapatite and tetracalciumphosphate give rise to an excellent bone formation, while alpha-TCP and blanco titanium evoked remodeling and less bone contact.
Klein
C P
CP
Department of Biomaterials, ACTA, Free University, Amsterdam.
Patka
P
P
van der Lubbe
H B
HB
Wolke
J G
JG
de Groot
K
K
D000497:Alloys; D000818:Animals; D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D001842:Bone and Bones / Q000033:anatomy & histology / Q000601:surgery; D002130:Calcium Phosphates; D004285:Dogs; D017886:Durapatite; D006882:Hydroxyapatites; D008422:Materials Testing; D019736:Prostheses and Implants; D013499:Surface Properties; D014025:Titanium
D000497:Alloys; D001672:Biocompatible Materials; D002130:Calcium Phosphates; D006882:Hydroxyapatites; C031462:titanium alloy (TiAl6V4); D017886:Durapatite; D014025:Titanium