Routine applications of DNA fingerprinting with the oligonucleotide probe (CAC)5/(GTG)5.
The use of DNA fingerprinting with synthetic oligonucleotides is illustrated for practical applications familiar in clinical diagnostics: pre- and postnatal zygosity determination and the monitoring of bone marrow transplantation. A simple method for non-radioactive detection is described which may be interesting for many diagnostic laboratories.
Neitzel
H
H
Institut für Humangenetik, Universitätsklinikum Rudolf Virchow, Berlin, Germany.
Digweed
M
M
Nürnberg
P
P
Pöpperl
A
A
Schmidt
C A
CA
Tinschert
S
S
Sperling
K
K
D016026:Bone Marrow Transplantation; D002648:Child; D004247:DNA; D016172:DNA Fingerprinting / Q000295:instrumentation / Q000379:methods*; D004262:DNA Restriction Enzymes; D005260:Female; D006650:Histocompatibility Testing / Q000379:methods; D006801:Humans; D008297:Male; D009693:Nucleic Acid Hybridization; D015345:Oligonucleotide Probes; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods; D014427:Twins / Q000235:genetics
D015345:Oligonucleotide Probes; D004247:DNA; D004262:DNA Restriction Enzymes