A double-blind, parallel, comparative evaluation of amlodipine against captopril in the monotherapeutic treatment of mild and moderate essential hypertension: interim results.
Amlodipine (once daily) and captopril (twice daily) had comparable efficacy and safety in reducing the blood pressure of patients with mild and moderate essential hypertension. Amlodipine administered once daily is an effective and well-tolerated treatment.
Velasco
M
M
Vargas Hospital, Caracas, Venezuela.
Hernández
R
R
Urbina
A
A
Hernández
O
O
Guevara
J
J
D017311:Amlodipine; D001794:Blood Pressure / Q000187:drug effects; D002121:Calcium Channel Blockers / Q000008:administration & dosage*; D002216:Captopril / Q000008:administration & dosage*; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000008:administration & dosage / Q000031:analogs & derivatives*
D002121:Calcium Channel Blockers; D017311:Amlodipine; D002216:Captopril; D009543:Nifedipine