Concomitant incidence of fertility chance reducing varicocele and chromosome aberration.
Authors describe the case of a male patient with varicocele, oligozoospermatism and subfertility, a 46 XY t (8; 10) (q22; p15) balanced chromosome carrier. Following varicectomy, successful pregnancy has developed even with balanced translocation meaning only 50% fertility chance. Prenatal diagnostics by chorion biopsy showed a fetus of normal chromosome constellation. Authors call attention to the fact that even minor, step-by-step improvements in fertility chance may lead to success in multiple aberrations.
Béres
J
J
Béla Johan National Institute of Public Health, Department of Human Genetics and Teratology, WHO Cooperative Center for Social Prevention of Hereditary Diseases, Budapest, Hungary.
Papp
G
G
D000328:Adult; D006801:Humans; D007248:Infertility, Male / Q000150:complications* / Q000235:genetics; D007621:Karyotyping; D008297:Male; D009845:Oligospermia / Q000150:complications; D014178:Translocation, Genetic; D014646:Varicocele / Q000150:complications*