[Coagulation and fibrinolytic activity of blood from the corpus cavernosum].
Thrombosis in cavernous bodies during erection-induced blood stasis is a exceptional phenomenon. This observation, induced the Authors to study coagulative and fibrinolytic activities of blood in cavernous bodies during pharmacologically induced erection. The results of the tests performed show that the blood of cavernous bodies has a fibrinolytic activity 3 times higher than peripheral blood (FPLA = 277 +- 83 mm2) and did not decrease when plasma was incubated with anti t-PA. During middle length erections, this activity is not expressed and the absence of thrombi formation seems to be due to a slowing of blood coagulation processes. On the other hand, during long-lasting erections, fibrinolysis is induced resulting in a local consumption like coagulopathy. Fibrinolysis in this district is not related to high t-PA plasma levels.
Rolle
L
L
Dipartimento di Scienze Cliniche e Biologiche, Università di Torino.
Bazzan
M
M
Bellina
M
M
Fontana
D
D
D000328:Adult; D001777:Blood Coagulation; D065427:Factor Xa Inhibitors; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D005342:Fibrinolysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D010208:Papaverine / Q000494:pharmacology; D010410:Penile Erection / Q000187:drug effects / Q000502:physiology*; D010413:Penis / Q000098:blood supply*; D013997:Time Factors
D065427:Factor Xa Inhibitors; D005338:Fibrin Fibrinogen Degradation Products; D010208:Papaverine
L'attività coagulativa e fibrinolitica del sangue del corpo cavernoso.