title: A biorhythm in the humoral immune response to SRBC in mice.
abstract: We reveal an existence of a biorhythm in the humoral immune response to SRBC in vivo and in vitro, basing on our experimental data registered in the years 1978-1991. It appears that the immune response to SRBC undergoes regular cycles of high and low responsiveness with 4-week intervals. The biorhythm is not dependent on sex or strain of mice. The importance of the phenomenon in the laboratory practice is discussed.
authors.affiliation: Department of Experimental Therapy, Polish Academy of Sciences, Wrocław.
authors.forename: M
authors.initials: M
authors.lastname: Zimecki
authors.forename: Z
authors.initials: Z
authors.lastname: Wieczorek
mesh_terms: D000818:Animals; D000917:Antibody Formation; D000921:Antibody-Producing Cells / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology; D005260:Female; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D010507:Periodicity; D012621:Seasons; D012756:Sheep