title: [Fractionation of a chalone-containing substance from Ehrlich's ascites tumor using high pressure chromatography].
abstract: The effect of various fractions of chalone--containing preparation from ascyte Ehrlich's tumour obtained by high performance liquid chromatography (HPLC) on mitotic activity and DNA synthesis in the tumour has been studied. After filtration the division of active chalone component which inhibits entering cells into M-phase and S-phase took place. The component inhibiting DNA synthesis eluated with G1-chalone.
authors.forename: N Ia
authors.initials: NIa
authors.lastname: Popova
authors.forename: A I
authors.initials: AI
authors.lastname: Antokhin
authors.forename: N V
authors.initials: NV
authors.lastname: Adrianov
authors.forename: L Z
authors.initials: LZ
authors.lastname: Tret'iakova
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Romanov
mesh_terms: D000818:Animals; D002286:Carcinoma, Ehrlich Tumor / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D004247:DNA / Q000096:biosynthesis / Q000187:drug effects; D006131:Growth Inhibitors / Q000032:analysis* / Q000494:pharmacology; D008297:Male; D051379:Mice; D008938:Mitosis / Q000187:drug effects; D016196:S Phase / Q000187:drug effects
chemical_list: D006131:Growth Inhibitors; D004247:DNA
vernacular_title: Fraktsionirovanie keĭlonsoderzhashchego preparata iz astsitnoĭ opukholi érlikha s pomoshch'iu khromatografii vysodogo davleniia.