Medical treatment of ectopic pregnancy.
Methotrexate is an alternative to surgical treatment of unruptured tubal pregnancy. Among 39 women with the diagnosis of tubal pregnancy there were ten cases without rupture of the salpinx. Nine out of these were treated with methotrexate. In one case there was a tubal rupture immediately after the termination of the treatment. There were no major side effects from the treatment with methotrexate. Tubal patency was tested for laparoscopically three months after the treatment. There was patency of all previously affected tubes.
Byrjalsen
C
C
Department of Obstetrics and Gynaecology, County Hospital, Herning, Denmark.
Toft
B
B
D000293:Adolescent; D000328:Adult; D006063:Chorionic Gonadotropin / Q000097:blood; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D010535:Laparoscopy; D008727:Methotrexate / Q000008:administration & dosage* / Q000009:adverse effects; D011247:Pregnancy; D011274:Pregnancy, Tubal / Q000097:blood / Q000188:drug therapy*; D012189:Retrospective Studies; D012422:Rupture, Spontaneous
D006063:Chorionic Gonadotropin; D008727:Methotrexate