A model for cortical 40 Hz oscillations invokes inter-area interactions.
Computer simulation of the dynamics of neuronal assemblies within minicolumns, and of the interactions between minicolumns in different cortical areas, has produced a quantitative explanation of the 35-60 Hz oscillations recently observed in adult cat striate cortices. The observed behavior suggests an association mechanism that exploits the NMDA receptor's properties. Detectable oscillations are predicted in cortical areas not directly stimulated, provided these are associatively linked with areas receiving sensory input.
Cotterill
R M
RM
Division of Biophysics, Technical University of Denmark, Lyngby.
Nielsen
C
C
D000818:Animals; D002415:Cats; D002540:Cerebral Cortex / Q000166:cytology* / Q000502:physiology; D003198:Computer Simulation; D003712:Dendrites / Q000502:physiology; D008959:Models, Neurological; D009475:Neurons, Afferent / Q000502:physiology*; D016194:Receptors, N-Methyl-D-Aspartate / Q000502:physiology; D012032:Refractory Period, Electrophysiological / Q000502:physiology; D013569:Synapses / Q000502:physiology
D016194:Receptors, N-Methyl-D-Aspartate