[Hexakis, (t-butylisonitryl/technetium, 99mTc-TBI), a cold-focal cardiac radiopharmaceutic agent and its distribution in the body].
The distribution of coldfocal cardiopharmacological substance 99mTc-TBI has been studied on a total of 14 dogs in relation to the healthy heart tissue. The quality heart scan resulted from the use of 99mTc-TBI. It may be performed 30 min after the administration of mentioned substance, when its blood activity is smaller than 10% activity of myocardium From the other organs, the myocardium scan may be influenced negatively with only liver which achieves 200% activity of left heart ventricle what is evidently consequential in worse imaging of "lower" ischemic lesions. These results justify us to conclude that the 99mTc-TBI is a substance suitable for scintigraphical imaging of myocardium.
Hadas
L
L
Vosecková
A
A
Duska
F
F
Vizda
J
J
Kafka
P
P
Urbanová
E
E
D000818:Animals; D004285:Dogs; D006321:Heart / Q000000981:diagnostic imaging*; D009570:Nitriles; D015609:Organotechnetium Compounds / Q000493:pharmacokinetics*; D011877:Radionuclide Imaging; D014018:Tissue Distribution
D009570:Nitriles; D015609:Organotechnetium Compounds; C043714:technetium Tc 99m hexakis(tert-butylisonitrile)
Studenoloziskové srdecní radiofarmakon Hexakis (t-Butylisonitryl/Technetium (99mTc-TBI) a jeho distribuce v organismu.