title: The treatment of precocious puberty.
abstract: Long-acting GnRH agonists are the treatment of choice for central precocious puberty. GnRH agonists are not effective in peripheral precocious puberty, but a number of other agents, including medroxyprogesterone acetate, ketoconazole, testolactone, and androgen antagonists, may be useful.
authors.affiliation: Department of Pediatrics, University of California, School of Medicine, Davis.
authors.forename: M D
authors.initials: MD
authors.lastname: Wheeler
authors.forename: D M
authors.initials: DM
authors.lastname: Styne
mesh_terms: D000726:Androgen Antagonists / Q000627:therapeutic use; D003692:Delayed-Action Preparations; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D007654:Ketoconazole / Q000627:therapeutic use; D008297:Male; D008525:Medroxyprogesterone / Q000031:analogs & derivatives / Q000627:therapeutic use; D017258:Medroxyprogesterone Acetate; D011629:Puberty, Precocious / Q000188:drug therapy* / Q000523:psychology; D013738:Testolactone / Q000627:therapeutic use
chemical_list: D000726:Androgen Antagonists; D003692:Delayed-Action Preparations; D007987:Gonadotropin-Releasing Hormone; D013738:Testolactone; D017258:Medroxyprogesterone Acetate; D008525:Medroxyprogesterone; D007654:Ketoconazole