Risk of tuberculosis in patients with HIV-I and HIV-II infections in Abidjan, Ivory Coast.
OBJECTIVE
To examine the association between HIV-II infection and tuberculosis.


METHODS
Cross sectional study comparing the prevalence of HIV-I and HIV-II infections in patients with tuberculosis and in blood donors.


METHODS
Abidjan, Ivory Coast, west Africa.


METHODS
2043 consecutive ambulant patients with tuberculosis (confirmed pulmonary, presumed pulmonary, or extrapulmonary) and 2127 volunteer blood donors.


METHODS
Prevalence of HIV-I and HIV-II infections as assessed by presence of serum antibodies.


RESULTS
Overall rates of HIV infection were 40.2% in patients with tuberculosis (26.4% positive for HIV-I, 4.7% for HIV-II, and 9.0% for both); and 10.4% in blood donors (7.2% positive for HIV-I, 1.9% for HIV-II, and 1.3% for both). HIV-II infection was significantly more common in patients with all types of tuberculosis than in blood donors (97/2043, 4.7% v 40/2127, 1.9%; odds ratio 3.8%, 95% confidence interval 2.6 to 5.6).


CONCLUSIONS
Both HIV-I and HIV-II infections are associated with tuberculosis in Abidjan. 35% of adult tuberculosis in Abidjan is attributable to HIV infection and 4% specifically to HIV-II.
De Cock
K M
KM
Division of HIV and AIDS, Centers for Disease Control, Atlanta, Georgia.
Gnaore
E
E
Adjorlolo
G
G
Braun
M M
MM
Lafontaine
M F
MF
Yesso
G
G
Bretton
G
G
Coulibaly
I M
IM
Gershy-Damet
G M
GM
Bretton
R
R
D000328:Adult; D001782:Blood Donors; D007560:Cote d'Ivoire; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology; D015497:HIV-1; D015498:HIV-2; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D015995:Prevalence; D012307:Risk Factors; D014376:Tuberculosis / Q000150:complications*; D014397:Tuberculosis, Pulmonary / Q000150:complications