Review and hypothesis: Alzheimer disease and Down syndrome--chromosome 21 nondisjunction may underlie both disorders.
Potter
H
H
Department of Neurobiology, Harvard Medical School, Boston, MA 02115.
D000375:Aging / Q000235:genetics; D000544:Alzheimer Disease / Q000235:genetics*; D000782:Aneuploidy; D002891:Chromosomes, Human, Pair 21; D004314:Down Syndrome / Q000235:genetics*; D006801:Humans; D008938:Mitosis; D014314:Trisomy