title: Serine/threonine kinases in the nervous system.
abstract: Three principal serine/threonine kinases that catalyze protein phosphorylation in response to second messengers are: cAMP-dependent protein kinase, multifunctional Ca2+/calmodulin-dependent protein kinase, and protein kinase C. Studies are now focusing on the distinct isoforms of these kinases that may subserve specific functions in some systems, and on providing a more molecular understanding of kinase functions. Combined genetic and biochemical approaches are beginning to be used to define unique roles for these kinases.
authors.affiliation: Department of Pharmacology, Stanford University School of Medicine, California 94305-5332.
authors.forename: H
authors.initials: H
authors.lastname: Schulman
mesh_terms: D000818:Animals; D006801:Humans; D009420:Nervous System / Q000201:enzymology*; D009424:Nervous System Physiological Phenomena; D011494:Protein Kinases / Q000502:physiology*; D017346:Protein Serine-Threonine Kinases
chemical_list: D011494:Protein Kinases; D017346:Protein Serine-Threonine Kinases