title: CHILD syndrome: fibroblasts from involved skin fail to proliferate in response to interleukin 1a due to induction of excessive prostaglandin E2 synthesis.
authors.affiliation: Department of Dermatology, Veterans Administration Medical Center, San Francisco, California.
authors.forename: M E
authors.initials: ME
authors.lastname: Goldyne
authors.forename: L
authors.initials: L
authors.lastname: Rea
authors.forename: S Z
authors.initials: SZ
authors.lastname: Goldyne
mesh_terms: D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D015232:Dinoprostone / Q000096:biosynthesis*; D005347:Fibroblasts / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D016113:Ichthyosiform Erythroderma, Congenital / Q000378:metabolism / Q000473:pathology*; D007213:Indomethacin / Q000494:pharmacology; D007375:Interleukin-1 / Q000494:pharmacology*; D017880:Limb Deformities, Congenital; D011994:Recombinant Proteins / Q000494:pharmacology; D012867:Skin / Q000378:metabolism* / Q000473:pathology; D013577:Syndrome
chemical_list: D007375:Interleukin-1; D011994:Recombinant Proteins; D015232:Dinoprostone; D007213:Indomethacin