[Effects of atrial natriuretic factor on proliferative response and natural cytotoxicity of human lymphocytes].
Effect of synthetic analogues of atrial natriuretic factor (ANF) on proliferative response and natural cytotoxic lymphocytes of human subjects was investigated in vitro. ANF-III and ANF-IV increased blast transformation lymphocytes induced by a Con-A suboptimal dose. The increase of cells activity was comparable with the effect of interleukin-2, added at a dose of 50-100 unit/ml.
Gracheva
L A
LA
Aleksandrova
E N
EN
Nasonov
E L
EL
Bespalova
Zh D
ZhD
Ovchinnikov
M V
MV
Vinogradov
V A
VA
Titov
M I
MI
D009320:Atrial Natriuretic Factor; D001782:Blood Donors; D002311:Cardiomyopathy, Dilated / Q000276:immunology; D002478:Cells, Cultured; D003208:Concanavalin A / Q000494:pharmacology; D003601:Cytotoxicity Tests, Immunologic; D003602:Cytotoxicity, Immunologic; D006801:Humans; D007376:Interleukin-2 / Q000494:pharmacology; D008213:Lymphocyte Activation / Q000187:drug effects*
D007376:Interleukin-2; C472955:NPPA protein, human; D003208:Concanavalin A; D009320:Atrial Natriuretic Factor
Vliianie atrial'nogo natriĭureticheskogo faktora na proliferatvnyĭ otvet i estestvennuiu tsitotoksichnost' limfotsitov cheloveka.