title: Sequence and localization of the gene encoding yeast phosphoglycerate mutase.
abstract: In this study we report on the complete nucleotide sequence of the yeast phosphoglycerate mutase gene (GPM1) and its essential 5' and 3' non-coding regions. The transcriptional start points were determined by S1-mapping and sequencing of a cDNA clone. Several sequences identified as important for transcriptional regulation in yeast promoters are present upstream of the transcription start point. 3' to the coding region we sequenced a composite repetitive element which, apparently, originated from a recombination between a delta- and a tau-element. Finally, we mapped the GPM1 gene 13 cM distal to fas1 on chromosome XI.
authors.affiliation: Department of Genetics, University of Alberta, Edmonton, Canada.
authors.forename: J
authors.initials: J
authors.lastname: Heinisch
authors.forename: R C
authors.initials: RC
authors.lastname: von Borstel
authors.forename: R
authors.initials: R
authors.lastname: Rodicio
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D001731:Bisphosphoglycerate Mutase / Q000235:genetics* / Q000378:metabolism; D003001:Cloning, Molecular; D004271:DNA, Fungal; D008969:Molecular Sequence Data; D012091:Repetitive Sequences, Nucleic Acid; D015183:Restriction Mapping; D012441:Saccharomyces cerevisiae / Q000201:enzymology / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D014158:Transcription, Genetic
chemical_list: D004271:DNA, Fungal; D001731:Bisphosphoglycerate Mutase