title: Laparoscopic cholecystectomy in anticoagulated patients.
abstract: Although minimally surgically invasive, laparoscopic surgery has yet to be proven safe in patients receiving anticoagulants. Retrospectively, the laparoscopic management of four patients requiring anticoagulation for cardiac valvular prostheses or chronic atrial fibrillation was reviewed with regard to potential hemorrhagic complications. Warfarin was discontinued preoperatively in all cases. Heparin anticoagulation was individualized according to each patient's risk for thrombosis. Laparoscopic cholecystectomy and intraoperative cholangiography were completed in each patient without resulting hemorrhagic complications. The operative management of patients exhibiting cholecystitis may be complicated by anticoagulation therapy required for preexisting conditions/diseases such as cardiac valve prostheses, chronic atrial fibrillation, deep venous thrombosis, and pulmonary embolism. The minimally invasive nature of laparoscopic surgery lends itself well to cholecystectomy required in the face of anticoagulation treatment. This limited initial series of selected patients demonstrates the feasibility and efficacy of laparoscopic cholecystectomy in patients receiving anticoagulants.
authors.affiliation: Department of Surgery, St. Louis University School of Medicine, MO 63110-0250.
authors.forename: S D
authors.initials: SD
authors.lastname: Fitzgerald
authors.forename: P V
authors.initials: PV
authors.lastname: Bailey
authors.forename: G J
authors.initials: GJ
authors.lastname: Liebscher
authors.forename: C H
authors.initials: CH
authors.lastname: Andrus
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use*; D002763:Cholecystectomy / Q000379:methods*; D002764:Cholecystitis / Q000150:complications / Q000601:surgery*; D002769:Cholelithiasis / Q000150:complications / Q000601:surgery*; D005260:Female; D006349:Heart Valve Diseases / Q000150:complications / Q000188:drug therapy; D006470:Hemorrhage / Q000139:chemically induced / Q000517:prevention & control*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000139:chemically induced / Q000517:prevention & control*
chemical_list: D000925:Anticoagulants