title: Synthesis and structure-activity relationships of a series of substituted-phenylpropionic acids as a novel class of leukotriene B4 antagonists.
authors.affiliation: Minase Research Institute, Ono Pharmaceutical Co., Ltd., Osaka, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Konno
authors.forename: S
authors.initials: S
authors.lastname: Sakuyama
authors.forename: T
authors.initials: T
authors.lastname: Nakae
authors.forename: N
authors.initials: N
authors.lastname: Hamanaka
authors.forename: T
authors.initials: T
authors.lastname: Miyamoto
authors.forename: A
authors.initials: A
authors.lastname: Kawasaki
mesh_terms: D000818:Animals; D001667:Binding, Competitive; D007975:Leukotriene B4 / Q000037:antagonists & inhibitors* / Q000378:metabolism; D009504:Neutrophils / Q000378:metabolism; D010666:Phenylpropionates / Q000138:chemical synthesis / Q000494:pharmacology*; D051381:Rats; D011971:Receptors, Immunologic / Q000378:metabolism; D018102:Receptors, Leukotriene B4; D013329:Structure-Activity Relationship
chemical_list: D010666:Phenylpropionates; D011971:Receptors, Immunologic; D018102:Receptors, Leukotriene B4; C067523:ONO-LB 457; D007975:Leukotriene B4