title: Evaluation of Ayush-64 for blood schizontocidal activity against rodent and simian malaria parasites.
abstract: Ayush-64, a new herbal antimalarial drug developed by the Central Council for Ayurveda and Siddha, was evaluated for direct parasiticidal action against P. berghei and P. yoelii nigeriensis in swiss mice and P. cynomolgi B and P. knowlesi in rhesus monkeys. No blood schizontocidal activity could be demonstrated against any of the four malaria parasites.
authors.affiliation: Central Drug Research Institute, Chattar Manzil, Lucknow, India.
authors.forename: M
authors.initials: M
authors.lastname: Kazim
authors.forename: S K
authors.initials: SK
authors.lastname: Puri
authors.forename: G P
authors.initials: GP
authors.lastname: Dutta
authors.forename: M V
authors.initials: MV
authors.lastname: Narasimham
mesh_terms: D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use*; D008253:Macaca mulatta; D008288:Malaria / Q000188:drug therapy*; D051379:Mice; D010936:Plant Extracts / Q000627:therapeutic use*; D010946:Plants, Medicinal; D010962:Plasmodium berghei; D016789:Plasmodium cynomolgi; D016790:Plasmodium knowlesi; D010967:Plasmodium yoelii
chemical_list: D000962:Antimalarials; C076841:Ayush 64; D010936:Plant Extracts