title: Intraperitoneal chemotherapy for malignant peritoneal mesothelioma.
abstract: 4 patients with malignant peritoneal mesothelioma have been treated with intraperitoneal chemotherapy in the Netherlands Cancer Institute in the recent years. 1 patient achieved a complete remission for 36+ months and another patient had a partial remission that lasted for 10 months. Intraperitoneal chemotherapy alone or in combination with other treatment modalities may yield a response rate of 58% with 24% complete remissions in 70 patients reviewed in the literature. Although these data should be considered with caution because of the heterogenicity of the patient group treated, cisplatin-based intraperitoneal chemotherapy seems to be the best available treatment for malignant peritoneal mesothelioma at present.
authors.affiliation: Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam.
authors.forename: L T
authors.initials: LT
authors.lastname: Vlasveld
authors.forename: M P
authors.initials: MP
authors.lastname: Gallee
authors.forename: S
authors.initials: S
authors.lastname: Rodenhuis
authors.forename: B G
authors.initials: BG
authors.lastname: Taal
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D006801:Humans; D007274:Injections, Intraperitoneal; D008297:Male; D008654:Mesothelioma / Q000188:drug therapy* / Q000628:therapy; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000188:drug therapy* / Q000628:therapy
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin