title: Local thrombolysis and thromboaspiration in the treatment of acutely thrombosed arteriovenous hemodialysis fistulas.
abstract: Sixty-four thrombosed hemodialysis fistulas in 55 patients were treated by local low-dose infusion of urokinase, percutaneous angioplasty, and thromboaspiration. Lysis was initially successful in 38 cases (59%) without any negative side effects. At 1 year, 59% of these fistulas were still functional. When the procedures failed, surgery saved the vascular access in 17 cases. Local fibrinolysis combined with thromboaspiration and angioplasty provides a clinically useful means of access preservation.
authors.affiliation: Cardiovascular Department of Radiology, Paris 6th University, Broussais Hospital, France.
authors.forename: F
authors.initials: F
authors.lastname: Poulain
authors.forename: A
authors.initials: A
authors.lastname: Raynaud
authors.forename: P
authors.initials: P
authors.lastname: Bourquelot
authors.forename: C
authors.initials: C
authors.lastname: Knight
authors.forename: X
authors.initials: X
authors.lastname: Rovani
authors.forename: J C
authors.initials: JC
authors.lastname: Gaux
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000800:Angioplasty, Balloon; D001166:Arteriovenous Shunt, Surgical / Q000009:adverse effects*; D002408:Catheters, Indwelling; D002648:Child; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*; D012086:Reoperation; D013396:Suction; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000209:etiology / Q000628:therapy*; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use; D014654:Vascular Patency
chemical_list: D006493:Heparin; D014568:Urokinase-Type Plasminogen Activator