title: Bedside blood ketone body monitoring.
abstract: The use of a reagent strip and reflectance meter for the bedside measurement of 3-hydroxybutyrate during the clinical management of diabetic ketoacidosis is described. Comparison of this method with a laboratory enzymatic assay shows good correlation (r = 0.97, p less than 0.05). Initial use in acute ketoacidosis suggests that knowledge of hourly changes in 3-hydroxybutyrate levels could be helpful in determining the optimum insulin dose.
authors.affiliation: Sir George E. Clark Metabolic Unit, Royal Victoria Hospital, Belfast, UK.
authors.forename: M O
authors.initials: MO
authors.lastname: McBride
authors.forename: M
authors.initials: M
authors.lastname: Smye
authors.forename: G S
authors.initials: GS
authors.lastname: Nesbitt
authors.forename: D R
authors.initials: DR
authors.lastname: Hadden
mesh_terms: D020155:3-Hydroxybutyric Acid; D001786:Blood Glucose / Q000032:analysis; D016883:Diabetic Ketoacidosis / Q000097:blood* / Q000188:drug therapy; D006801:Humans; D006885:Hydroxybutyrates / Q000097:blood*; D007328:Insulin / Q000627:therapeutic use; D008991:Monitoring, Physiologic / Q000379:methods; D011934:Reagent Strips; D013997:Time Factors
chemical_list: D001786:Blood Glucose; D006885:Hydroxybutyrates; D007328:Insulin; D011934:Reagent Strips; D020155:3-Hydroxybutyric Acid