[Production of monoclonal antibodies against Leishmania mexicana mexicana antigens].
In the present work we obtained three mAbs specific against gp65 of the strain L. mexicana mexicana (NR). These three mAbs were able of recognizing promastigotes of L.m.m. not only for immunofluorescence but also by immunostain. In the immunohistochemistry of biopsies of patients with leishmaniasis, using the three mAbs, it was possible to observe the presence of amastigotes in the infected tissues.
Correnti
M
M
Escuela de Biología, Facultad de Ciencias, Universidad Central de Venezuela.
Ortega
G
G
D000818:Animals; D000911:Antibodies, Monoclonal / Q000096:biosynthesis*; D000953:Antigens, Protozoan / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D007894:Leishmania mexicana / Q000276:immunology* / Q000302:isolation & purification
D000911:Antibodies, Monoclonal; D000953:Antigens, Protozoan
Producción de anticuerpos monoclonales contra antígenos de Leishmania mexicana mexicana.