title: Pig herds having a single reactor to serum antibody tests to Aujeszky's disease virus.
abstract: The introduction of Aujeszky's disease virus into a herd of pigs usually results in a rapid spread of the virus and a high percentage of pigs become seropositive. However, herd monitoring for the virus occasionally reveals a single seropositive breeding pig, referred to as a single reactor. The seropositive status of single reactors may be due to previous vaccination against Aujeszky's disease, or to exposure to a field strain of the virus, or to a false positive reaction in the serological assay. During a monitoring programme in Minnesota, 30 pig herds with single serological reactors were detected. Twenty-seven of these single reactors from 19 herds were segregated from their herds immunosuppressed with dexamethasone. Aujeszky's disease virus was isolated from four of the 27 pigs. Three of the four herds subsequently had outbreaks of Aujeszky's disease, suggesting that some single reactors were infected with Aujeszky's disease virus and had the potential to spread the virus within and between herds.
authors.affiliation: Department of Agriculture, University of Minnesota, St Paul 55108.
authors.forename: J F
authors.initials: JF
authors.lastname: Annelli
authors.forename: R B
authors.initials: RB
authors.lastname: Morrison
authors.forename: S M
authors.initials: SM
authors.lastname: Goyal
authors.forename: M E
authors.initials: ME
authors.lastname: Bergeland
authors.forename: W J
authors.initials: WJ
authors.lastname: Mackey
authors.forename: D G
authors.initials: DG
authors.lastname: Thawley
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D005189:False Positive Reactions; D005260:Female; D005455:Fluorescent Antibody Technique / Q000662:veterinary; D011558:Herpesvirus 1, Suid / Q000276:immunology*; D007165:Immunosuppression Therapy / Q000662:veterinary; D008910:Minnesota; D011557:Pseudorabies / Q000635:transmission*; D013552:Swine / Q000276:immunology*; D013553:Swine Diseases / Q000635:transmission*
chemical_list: D000914:Antibodies, Viral