Genetic linkage studies of human neurodegenerative disorders.
Recombinant DNA technology has the ability to delineate the causes of several neurodegenerative disorders. Genetic linkage studies have been used successfully to localize gene defects and it is likely that in the near future the exact loci will be determined.
Tanzi
R E
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Molecular Neurogenetics Laboratory, Massachusetts General Hospital, Charlestown 02129.
D000544:Alzheimer Disease / Q000235:genetics; D000690:Amyotrophic Lateral Sclerosis / Q000235:genetics; D006801:Humans; D006816:Huntington Disease / Q000235:genetics; D009410:Nerve Degeneration / Q000502:physiology*; D009422:Nervous System Diseases / Q000235:genetics*