title: Acne vulgaris. Pathogenesis and treatment.
abstract: Acne vulgaris is a multifactorial disease involving abnormalities in follicular keratinization, sebum production, proliferation of Propionibacterium acnes, and inflammation. Treatment is directed toward reversing these underlying pathogenic factors. Therapeutic options include topical comedolytics, topical and systemic antibiotics, hormonal manipulations, and oral retinoids.
authors.affiliation: Department of Dermatology, State University of New York Health Science Center, Brooklyn.
authors.forename: M H
authors.initials: MH
authors.lastname: Winston
authors.forename: A R
authors.initials: AR
authors.lastname: Shalita
mesh_terms: D000152:Acne Vulgaris / Q000145:classification / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001585:Benzoyl Peroxide / Q000627:therapeutic use; D006728:Hormones / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D014212:Tretinoin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D006728:Hormones; D014212:Tretinoin; D001585:Benzoyl Peroxide