Localization of the TRK proto-oncogene to human chromosome bands 1q23-1q24.
A FER-related sequence isolated from a human genomic library was found to be homologous to TRK. In situ hybridization of a 0.92 kb probe, isolated from this sequence, localized the TRK gene to the long arm of chromosome 1 within bands 1q23-1q24. This is a significantly more proximal location of TRK than the 1q32-1q41 site published recently (Miozzo et al., 1990).
Morris
C M
CM
Cytogenetic and Molecular Oncology Unit, Christchurch Hospital, New Zealand.
Hao
Q L
QL
Heisterkamp
N
N
Fitzgerald
P H
PH
Groffen
J
J
D000595:Amino Acid Sequence; D001483:Base Sequence; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D015342:DNA Probes; D006801:Humans; D008969:Molecular Sequence Data; D015513:Oncogene Proteins / Q000235:genetics*; D000090063:Proto-Oncogene Mas
D015342:DNA Probes; C000715470:MAS1 protein, human; D015513:Oncogene Proteins; D000090063:Proto-Oncogene Mas; C065400:oncogene protein trk