Advantages of F(ab')2 fragments of anti-CD3 monoclonal antibody as compared to whole antibody as immunosuppressive agents in mice.
Hirsch
R
R
Experimental Immunology Branch, NCI, National Institutes of Health, Bethesda, MD 20892.
Bluestone
J A
JA
Bare
C V
CV
Gress
R E
RE
D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D000945:Antigens, Differentiation, T-Lymphocyte / Q000276:immunology*; D017252:CD3 Complex; D006084:Graft Rejection; D006085:Graft Survival; D007140:Immunoglobulin Fab Fragments / Q000627:therapeutic use*; D007165:Immunosuppression Therapy; D051379:Mice; D011948:Receptors, Antigen, T-Cell / Q000276:immunology*; D016038:Skin Transplantation / Q000276:immunology*; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology; D014184:Transplantation, Homologous
D000911:Antibodies, Monoclonal; D000945:Antigens, Differentiation, T-Lymphocyte; D017252:CD3 Complex; D007140:Immunoglobulin Fab Fragments; D011948:Receptors, Antigen, T-Cell