[Effect of ultrafiltrates in plasma from patients with chronic uremia on platelet aggregation].
An effect of 20 ultrafiltrates from patients with chronic renal failure on ADP-, epinephrine-, and arachidonic acid-induced platelet aggregation. Ultrafiltrates were collected at the beginning and the end of dialysis. It was found that ultrafiltrates collected at the beginning of dialysis decrease ADP-induced platelet aggregation whereas ultrafiltrates collected at the and of dialysis exert reverse effect. No effect on epinephrine- and arachidonic acid-induced platelet aggregation was seen. Removal of substances inhibiting platelet aggregation produced by ADP hemodialysis may reveal increased platelet aggregation in patients with uremia.
Myśliwiec
M
M
Kliniki Nefrologii AM, Białymstoku.
Popławski
A
A
Soszka
J
J
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000502:physiology*; D006435:Renal Dialysis
Wpływ ultrafiltratów osocza chorych na przewlekła mocznice na agregacje krwinek płytkowych.