Proline-directed protein phosphorylation and cell cycle regulation.
Recent discoveries have converged on the emerging enzymology that governs the G1-S phase transition of the mammalian somatic cell cycle. These discoveries have led to an appreciation of the regulatory role of proline-directed protein phosphorylation in molecular signalling, and have resulted in the identification of a putative proto-oncogene.
Hall
F L
FL
University of Southern California, Los Angeles.
Vulliet
P R
PR
D000818:Animals; D002453:Cell Cycle / Q000502:physiology*; D002471:Cell Transformation, Neoplastic; D016213:Cyclins / Q000378:metabolism; D006801:Humans; D010766:Phosphorylation; D011392:Proline / Q000378:metabolism*; D011494:Protein Kinases / Q000378:metabolism*; D000090063:Proto-Oncogene Mas; D015398:Signal Transduction
D016213:Cyclins; C000715470:MAS1 protein, human; D000090063:Proto-Oncogene Mas; D011392:Proline; D011494:Protein Kinases