Serum ferritin deficiency in Huntington's disease patients.
This study was designed to investigate serum levels of iron, ferritin, vitamin B12 and folic acid in 18 Huntington's disease patients and 86 healthy control subjects. Serum iron, vitamin B12 and folic acid levels were normal. Ferritin concentrations were significantly diminished in the choreic patients. The importance of this finding in our attempt to understand the underlying biochemical defect and the chemical nature of the iron deposits found in several brain nuclei in Huntington's disease patients is unknown.
Bonilla
E
E
Instituto de Investigaciones Clínicas, Facultad de Medicina, Universidad del Zulia, Venezuela.
Estévez
J
J
Suárez
H
H
Morales
L M
LM
Chacin de Bonilla
L
L
Villalobos
R
R
Dávila
J O
JO
D000293:Adolescent; D000328:Adult; D005260:Female; D005293:Ferritins / Q000097:blood / Q000172:deficiency*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D006816:Huntington Disease / Q000097:blood*; D008297:Male; D008875:Middle Aged
D006454:Hemoglobins; D005293:Ferritins