title: Enzymology of intracellular membrane fusion.
abstract: A combination of cell-free biochemical and morphological studies has revealed that a coated bud-coated vesicle transport system shuttles newly synthesized proteins through the successive processing compartments of the Golgi apparatus. These "Golgi coated vesicles" operate in a manner formally analogous to the clathrin coated pit-coated vesicle system responsible for receptor-mediated endocytosis; however Golgi coated vesicles do not contain clathrin.
authors.affiliation: Department of Molecular Biology, Princeton University, New Jersey.
authors.forename: J E
authors.initials: JE
authors.lastname: Rothman
mesh_terms: D001692:Biological Transport; D002352:Carrier Proteins / Q000378:metabolism; D006056:Golgi Apparatus / Q000378:metabolism; D007425:Intracellular Membranes / Q000201:enzymology*; D008561:Membrane Fusion; D008565:Membrane Proteins / Q000378:metabolism; D014721:Vesicular stomatitis Indiana virus / Q000378:metabolism
chemical_list: D002352:Carrier Proteins; D008565:Membrane Proteins