title: [Diagnostic utility of 111In-antimyosin Fab scintigraphy in acute myocardial infarction: comparison with 201Tl and 99mTc-pyrophosphate myocardial scintigraphy].
abstract: To assess the diagnostic accuracy, extent, and characteristics of 111In-antimyosin Fab scintigraphy (In-AM) in acute myocardial infarction (AMI), we studied In-AM in 17 patients with AMI and compared with In-AM, 99mTc-PYP and 201Tl scintigraphy. Intensity of In-AM uptake was classified into 3 grades. Fourteen of 17 patients (82%) showed positive uptake of In-AM. The locations of infarct area diagnosed by In-AM were in accordance with those by electrocardiography. There was a good correlation between the extent score of In-AM planar and that of SPECT (r = 0.72), In-AM SPECT and Tl SPECT (r = 0.79), In-AM planar and PYP planar (r = 0.92), In-AM SPECT and PYP SPECT (r = 0.76), respectively (p less than 0.01). Thus, In-AM is a useful method for diagnosis of AMI.
authors.affiliation: First Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya.
authors.forename: M
authors.initials: M
authors.lastname: Morita
authors.forename: H
authors.initials: H
authors.lastname: Naruse
authors.forename: J
authors.initials: J
authors.lastname: Yamamoto
authors.forename: M
authors.initials: M
authors.lastname: Itano
authors.forename: H
authors.initials: H
authors.lastname: Kawamoto
authors.forename: N
authors.initials: N
authors.lastname: Fukutake
authors.forename: M
authors.initials: M
authors.lastname: Ohyanagi
authors.forename: T
authors.initials: T
authors.lastname: Iwasaki
authors.forename: M
authors.initials: M
authors.lastname: Fukuchi
mesh_terms: D000328:Adult; D000368:Aged; D000911:Antibodies, Monoclonal; D005260:Female; D006801:Humans; D007140:Immunoglobulin Fab Fragments; D007205:Indium Radioisotopes; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging*; D009218:Myosins / Q000276:immunology*; D011237:Predictive Value of Tests; D016698:Technetium Tc 99m Pyrophosphate; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D000911:Antibodies, Monoclonal; D007140:Immunoglobulin Fab Fragments; D007205:Indium Radioisotopes; D013794:Thallium Radioisotopes; D016698:Technetium Tc 99m Pyrophosphate; D009218:Myosins