title: [Genetic load of hereditary diseases in populations of the Krasnodar Krai].
abstract: Medico-genetical study of populations living in Krasnodar district was carried out. The mean value of genetic load contributed by autosomal dominant diseases composed 0.92 +/- 0.06, this value being 0.56 +/- 0.04 for autosomal recessive and 0.36 +/- 0.05 for X-linked recessive disorders per one thousand. Comparative analysis of genetical load in urban and rural populations demonstrated that they had no differences in relation to genetical load contributed by autosomal recessive and X-linked recessive disorders. At the same time, significant differences were noted between the populations concerning genetic load contributed by autosomal-dominant disorders.
authors.forename: A N
authors.initials: AN
authors.lastname: Petrin
authors.forename: V I
authors.initials: VI
authors.lastname: Golubtsov
authors.forename: V A
authors.initials: VA
authors.lastname: Galkina
authors.forename: E K
authors.initials: EK
authors.lastname: Ginter
authors.forename: A A
authors.initials: AA
authors.lastname: Revazov
authors.forename: M V
authors.initials: MV
authors.lastname: Khisamova
authors.forename: L K
authors.initials: LK
authors.lastname: Mikhaĭlova
authors.forename: O V
authors.initials: OV
authors.lastname: Khlevnikova
authors.forename: G I
authors.initials: GI
authors.lastname: Sukolin
authors.forename: V V
authors.initials: VV
authors.lastname: Poleshchuk
mesh_terms: D005799:Genes, Dominant / Q000235:genetics; D005808:Genes, Recessive / Q000235:genetics; D030342:Genetic Diseases, Inborn / Q000235:genetics*; D008040:Genetic Linkage; D005828:Genetics, Population; D006801:Humans; D012423:Rural Health / Q000706:statistics & numerical data; D012426:Russia; D014504:Urban Health / Q000706:statistics & numerical data; D014960:X Chromosome
vernacular_title: Gruz nasledstvennykh bolezneĭ v populiatsiiakh Krasnodarskogo Kraia.