Effects of gonadotrophin on resistance to Listeria monocytogenes infection in mice.
It was demonstrated that exogenous GH suppressed the resistance to L. monocytogenes infection in Listeria resistant C57Bl/6 and susceptible A/J mice. However, different parameters of the immunological reaction to Listeria were affected by GH treatment in these mouse strains. In C57Bl/6 mice GH decreased accumulation of macrophages at the inflammatory site. On the contrary, a depression of anti-listerial activity of the phagocytes and a reduction of DTH reaction to Listeria antigen was demonstrated in GH treated A/J mice.
Rózalska
B
B
Department of Immunology, University of Lódź.
Klink
M
M
Wiewióra
A
A
Rudnicka
W
W
D000818:Animals; D000942:Antigens, Bacterial; D005260:Female; D006062:Gonadotropins / Q000494:pharmacology*; D007108:Immune Tolerance / Q000187:drug effects; D008089:Listeria monocytogenes / Q000276:immunology / Q000302:isolation & purification; D008088:Listeriosis / Q000276:immunology* / Q000382:microbiology; D051379:Mice; D008805:Mice, Inbred A; D008810:Mice, Inbred C57BL; D010587:Phagocytosis / Q000187:drug effects; D013154:Spleen / Q000276:immunology / Q000382:microbiology
D000942:Antigens, Bacterial; D006062:Gonadotropins