Ketoconazole-induced fulminant hepatitis necessitating liver transplantation.
The most serious side effect of ketoconazole is hepatitis, which has proved fatal in seven reported cases. We present a case of fulminant hepatic failure in a 45-year-old Oriental woman that probably would have been fatal except for a successful liver transplant. A review of the literature of fatalities associated with ketoconazole is presented.
Knight
T E
TE
Department of Medicine, John A. Burns School of Medicine, Honolulu, Hawaii.
Shikuma
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CY
Knight
J
J
D002177:Candidiasis / Q000188:drug therapy; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology* / Q000601:surgery; D005260:Female; D006801:Humans; D007654:Ketoconazole / Q000009:adverse effects*; D016031:Liver Transplantation; D008875:Middle Aged; D014009:Onychomycosis / Q000188:drug therapy
D007654:Ketoconazole