title: [Methods for ensuring the apyrogenic quality of injection solutions in hospital pharmacies].
abstract: The existing technology of water production cannot protect injections and solutions from foreign substances. The main ways of the solution contamination are: microbiotic pollution of distilled water, air and manmade pollution. The article deals with a problem of removing pyrogenic substances from parenteral solutions. A special attention is paid to the methods of electrofiltration and ultrafiltration by means of a membrane filter (Soviet production). The authors emphasize the importance of a strict control over pyrogenic tests of injections. The appropriate factory facilities and essential hygienic and sanitary conditions in manufacturing injections will rule out the possibility of its microbiotic pollution.
authors.forename: A A
authors.initials: AA
authors.lastname: Eroshevskiĭ
authors.forename: P F
authors.initials: PF
authors.lastname: Khveshchuk
authors.forename: L D
authors.initials: LD
authors.lastname: Riabykh
mesh_terms: D004340:Drug Contamination / Q000517:prevention & control*; D006772:Hospitals, Military; D006801:Humans; D007267:Injections / Q000592:standards*; D008722:Methods; D010607:Pharmacy Service, Hospital; D011749:Pyrogens / Q000302:isolation & purification*; D012996:Solutions; D014586:USSR
chemical_list: D011749:Pyrogens; D012996:Solutions
vernacular_title: Sposoby obespecheniia apirogennosti in''ektsionnykh rastvorov v aptekakh lechebnykh uchrezhdeniĭ.