title: Determination of clarithromycin as a contaminant on surfaces by high-performance liquid chromatography using electrochemical detection.
abstract: Microgram levels of clarithromycin residues on various surfaces are quantitated. After cleaning, any residual clarithromycin remaining is removed from the surface by a wet swab-dry swab technique. High-performance liquid chromatography with electrochemical detection is used for quantitation of the resulting solutions. Recoveries ranged from 93 to 118%.
authors.affiliation: Analytical Research Department, Abbott Laboratories, North Chicago, Illinois 60064.
authors.forename: T D
authors.initials: TD
authors.lastname: Rotsch
authors.forename: M
authors.initials: M
authors.lastname: Spanton
authors.forename: P
authors.initials: P
authors.lastname: Cugier
authors.forename: A C
authors.initials: AC
authors.lastname: Plasz
mesh_terms: D002851:Chromatography, High Pressure Liquid; D017291:Clarithromycin; D004340:Drug Contamination; D004563:Electrochemistry; D004917:Erythromycin / Q000031:analogs & derivatives* / Q000032:analysis
chemical_list: D004917:Erythromycin; D017291:Clarithromycin