title: Immune response to hepatitis B vaccine in premature neonates.
abstract: The immunogenecity of a recombinant yeast-derived hepatitis B vaccine in 25 premature infants who were born to HBsAg negative mothers was studied. The gestational ages were 28-37 weeks and birth weights were 1300-2000 grams. Seroconversion occurred in 22 infants, the anti HBs titers varied between 50 and 13,470 IU/L (Geometric mean titer = 542 IU/L). Seroconversion rate = 88%. The response did not vary with gestational age, birth weight or illness status.
authors.affiliation: Department of Pediatrics, Bangkok Christian Hospital, Thailand.
authors.forename: S
authors.initials: S
authors.lastname: Chawareewong
authors.forename: A
authors.initials: A
authors.lastname: Jirapongsa
authors.forename: K
authors.initials: K
authors.lastname: Lokaphadhana
mesh_terms: D006510:Hepatitis B Antibodies / Q000096:biosynthesis*; D006514:Hepatitis B Surface Antigens / Q000276:immunology*; D017325:Hepatitis B Vaccines; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000276:immunology*; D014614:Vaccines, Synthetic / Q000008:administration & dosage / Q000276:immunology*; D014761:Viral Hepatitis Vaccines / Q000008:administration & dosage / Q000276:immunology*
chemical_list: D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D017325:Hepatitis B Vaccines; D014614:Vaccines, Synthetic; D014761:Viral Hepatitis Vaccines