title: [Nucleolus organizer regions and ploidy pattern of DNA in stomach neoplasms].
abstract: We studied 20 gastric adenocarcinoma to determine DNA ploidy pattern by flow cytometry and nucleolar organizer regions by the colloidal silver method. There were 12 diffuse and 8 intestinal type lesions. 11 tumors were classified as diploid and 9 as aneuploid. No correlation was observed between DNA ploidy pattern and mean number of nucleolar organizer regions. The histologic type was significantly related to the number of nucleolar organizer regions (p < 0.01). Poorly differentiated lesions had significantly less nucleolar organizer regions than intestinal type lesions. Lesions with ring cells (n = 6) had similar number of nucleolar organizer regions than poorly differentiated lesions.
authors.affiliation: Unidad de Anatomía Patológica y Citopatología, Facultad de Medicina, Universidad de La Frontera, Hospital Regional de Temuco, Chile.
authors.forename: I
authors.initials: I
authors.lastname: Roa
authors.forename: J C
authors.initials: JC
authors.lastname: Araya
authors.forename: X
authors.initials: X
authors.lastname: de Aretxabala
authors.forename: I
authors.initials: I
authors.lastname: Wistuba
authors.forename: M
authors.initials: M
authors.lastname: Villaseca
mesh_terms: D000230:Adenocarcinoma / Q000648:ultrastructure*; D004273:DNA, Neoplasm / Q000032:analysis*; D005434:Flow Cytometry; D006801:Humans; D009697:Nucleolus Organizer Region / Q000473:pathology*; D011003:Ploidies; D013274:Stomach Neoplasms / Q000648:ultrastructure*
chemical_list: D004273:DNA, Neoplasm
vernacular_title: Regiones del organizador nucleolar y patrón de ploidía del ADN en el cáncer gástrico.