title: Successful treatment of focal hepatic candidiasis in a patient with acute myeloid leukaemia.
abstract: A 38-year-old woman with acute myeloid leukaemia developed focal hepatic candidiasis. Ultrasonography and computerised tomography revealed the hepatic lesion and definite diagnosis was established by percutaneous liver biopsy. The use of a cumulative dose of 6.6 g of amphotericin B in combination with 5-fluorocytosine resulted in successful eradication of the fungus. The difficulties in making an antemortem diagnosis are well recognised and optimal therapy of the condition remains to be defined.
authors.affiliation: Department of Medicine, Queen Mary Hospital, University of Hong Kong.
authors.forename: E
authors.initials: E
authors.lastname: Tsui
authors.forename: R
authors.initials: R
authors.lastname: Liang
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use*; D002177:Candidiasis / Q000175:diagnosis / Q000188:drug therapy*; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D005437:Flucytosine / Q000627:therapeutic use*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008107:Liver Diseases / Q000175:diagnosis / Q000188:drug therapy*; D012074:Remission Induction; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D000666:Amphotericin B; D005437:Flucytosine