Renographic diagnosis of renovascular hypertension with angiotensin converting enzyme inhibition and furosemide.
Captopril renography is a powerful tool for evaluating renovascular hypertension. In this article we examine four different protocols: 99mTc-DTPA, [131I]hippuran with captopril, [131I]hippuran with enalaprilat, and 99mTc-mercaptoacetyltriglycine (MAG3). In our experience, [131I]hippuran renograms are a reliable and reproducible test in patients both with and without azotemia. Although our experience with the new 99mTc-MAG3 technique is somewhat limited, it appears that this will also be a valuable test, which additionally has several advantages over hippuran, namely, a smaller turnaround time between test and baseline study, a smaller dose of radioactivity, better images, and more accurate counts. We look forward to the future development of this technique.
Sfakianakis
G N
GN
University of Miami/Jackson Memorial Medical Center, Florida.
Bourgoignie
J J
JJ
D000800:Angioplasty, Balloon; D000806:Angiotensin-Converting Enzyme Inhibitors; D002985:Clinical Protocols; D005665:Furosemide; D006801:Humans; D006978:Hypertension, Renovascular / Q000000981:diagnostic imaging* / Q000628:therapy; D007457:Iodine Radioisotopes; D007465:Iodohippuric Acid; D009842:Oligopeptides; D015609:Organotechnetium Compounds; D011859:Radiography; D011866:Radioisotope Renography / Q000379:methods*; D012077:Renal Artery / Q000000981:diagnostic imaging; D017263:Technetium Tc 99m Mertiatide
D000806:Angiotensin-Converting Enzyme Inhibitors; D007457:Iodine Radioisotopes; D009842:Oligopeptides; D015609:Organotechnetium Compounds; D007465:Iodohippuric Acid; D017263:Technetium Tc 99m Mertiatide; D005665:Furosemide