title: [Mesenteric and portal vein thrombosis following splenectomy in hematologic diseases. Apropos of 3 cases].
abstract: Mesenterico-portal venous thrombosis following hematological splenectomy is infrequent. We report about three cases successfully treated with heparin. A review of the literature allows identifying three factors acting in the etiopathogenesis of such thrombosis: alteration of blood composition, blood stasis and injuries to the vascular walls. The diagnosis is confirmed by ultrasonography and abdominal CT, and echo-Doppler will play a more important role in the future. The treatment of mesenterico-portal thrombosis is mainly medical, with surgery being indicated only in case of intestinal necrosis. An anticoagulant or platelet-suppressive treatment and the ligation of the splenic vein as close as possible to its junction with the mesenteric vein may be proposed as preventive measures.
authors.affiliation: Clinique chirurgicale C, Hôpitaux de Brabois, Nancy, Vandoeuvre.
authors.forename: P
authors.initials: P
authors.lastname: Boissel
authors.forename: L
authors.initials: L
authors.lastname: Bresler
authors.forename: G
authors.initials: G
authors.lastname: Trackoen
authors.forename: D
authors.initials: D
authors.lastname: Poussot
authors.forename: J
authors.initials: J
authors.lastname: Grosdidier
mesh_terms: D006402:Hematologic Diseases / Q000601:surgery*; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008641:Mesenteric Vascular Occlusion / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D008642:Mesenteric Veins; D008875:Middle Aged; D011169:Portal Vein; D013156:Splenectomy / Q000009:adverse effects*; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D014057:Tomography, X-Ray Computed
chemical_list: D006493:Heparin
vernacular_title: Les thromboses de l'axe mésentérico-porte après splénectomie pour affection hématologique. A propos de 3 observations.