title: Bradyarrhythmias and laparoscopy: a prospective study of heart rate changes with laparoscopy.
abstract: Cardiac arrhythmias are a common complication of laparoscopy. Brady-arrhythmias (including asystole) may be life-threatening. The recent introduction of new shorter-acting muscle relaxants (atracurium and vecuronium), with their lack of vagolytic activity, may exacerbate this situation. At the Royal Women's Hospital there have been several episodes of severe bradyarrhythmias and/or asystole associated with these relaxants. This study evaluated heart rate changes in 49 women during laparoscopy: 47% of patients had arrhythmias, 30% of these being bradyarrhythmias. Nearly all the episodes occurred during carbon dioxide insufflation or with traction on pelvic structures. The life-threatening nature of this phenomenon should be understood by all anaesthetists and gynaecologists engaged in laparoscopic procedures.
authors.affiliation: Royal Women's Hospital, Melbourne.
authors.forename: P S
authors.initials: PS
authors.lastname: Myles
mesh_terms: D000328:Adult; D000768:Anesthesia, General; D001145:Arrhythmias, Cardiac / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006339:Heart Rate; D006771:Hospitals, Maternity; D006801:Humans; D015994:Incidence; D010535:Laparoscopy / Q000009:adverse effects*; D008875:Middle Aged; D011446:Prospective Studies; D014739:Victoria / Q000453:epidemiology