title: A neutrophilic reaction of Sweet's syndrome type associated with the oral contraceptive.
abstract: A case is presented of a Sweet's syndrome-like eruption in association with the oral contraceptive. A 46 year old caucasian woman developed recurrent episodes of erythematous tender plaques on her trunk six weeks after commencement of the oral contraceptive (OC). Her condition clinically and histologically resembled Sweet's dermatosis. On cessation of the OC there was complete resolution of her lesions and she remains well 12 months later. This is the first report, to our knowledge, of a neutrophilic reaction to the oral contraceptive, and we believe that drugs may be implicated in the aetiology of atypical neutrophilic reactions simulating Sweet's syndrome in patients who are otherwise well.
authors.affiliation: Dermatology Centre, Lidcombe Hospital, NSW.
authors.forename: F J
authors.initials: FJ
authors.lastname: Tefany
authors.forename: K
authors.initials: K
authors.lastname: Georgouras
mesh_terms: D003282:Contraceptives, Postcoital, Hormonal / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D004997:Ethinyl Estradiol / Q000009:adverse effects*; D019304:Ethinyl Estradiol-Norgestrel Combination; D005260:Female; D005334:Fever / Q000209:etiology; D006801:Humans; D008875:Middle Aged; D009504:Neutrophils / Q000473:pathology*; D009644:Norgestrel / Q000009:adverse effects*; D012008:Recurrence; D016463:Sweet Syndrome / Q000139:chemically induced* / Q000473:pathology; D013577:Syndrome
chemical_list: D003282:Contraceptives, Postcoital, Hormonal; D009644:Norgestrel; D004997:Ethinyl Estradiol; D019304:Ethinyl Estradiol-Norgestrel Combination