title: Management of the painful and nodular breast.
abstract: Mild breast pain and nodularity are common and may be considered normal. Only when symptoms are severe enough to affect the patient's lifestyle should drug treatment be considered. Using danazol, bromocriptine or evening primrose oil a clinically useful improvement in pain can be anticipated in 77% of patients with cyclical mastalgia and 44% with non-cyclical mastalgia. Benign nodularity should not be biopsied surgically as it is unnecessary and makes subsequent assessment of the breast difficult.
authors.affiliation: University Department of Surgery, University Hospital of South Mancheser, UK.
authors.forename: C A
authors.initials: CA
authors.lastname: Gateley
authors.forename: R E
authors.initials: RE
authors.lastname: Mansel
mesh_terms: D000328:Adult; D000367:Age Factors; D001941:Breast Diseases / Q000188:drug therapy* / Q000503:physiopathology; D001971:Bromocriptine / Q000627:therapeutic use; D002064:Buserelin / Q000031:analogs & derivatives / Q000627:therapeutic use; D003613:Danazol / Q000627:therapeutic use; D015914:Estrogen Replacement Therapy; D005228:Fatty Acids, Essential / Q000627:therapeutic use; D005260:Female; D017273:Goserelin; D006801:Humans; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D008041:Linoleic Acids; D031665:Oenothera biennis; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D010938:Plant Oils; D013629:Tamoxifen / Q000627:therapeutic use; D017965:gamma-Linolenic Acid
chemical_list: D005228:Fatty Acids, Essential; D000960:Hypolipidemic Agents; D008041:Linoleic Acids; D010938:Plant Oils; D013629:Tamoxifen; D017273:Goserelin; D001971:Bromocriptine; C028498:evening primrose oil; D017965:gamma-Linolenic Acid; D003613:Danazol; D002064:Buserelin