title: Spinal leptomeningeal metastasis from cerebral glioblastoma. Appearance on magnetic resonance imaging.
abstract: A case of circumferential leptomeningeal metastasis to the spinal cord from an intracranial glioblastoma multiforme (spinal meningeal gliomatosis) is presented. The clinical, radiographic, and pathological features are described. Spinal magnetic resonance imaging with gadolinium-diethylenetriaminepentaacetic acid accurately demonstrated the spread of disease when compared with autopsy findings. The value of spinal magnetic resonance imaging in patients with symptoms attributable to cerebrospinal fluid metastases is discussed.
authors.affiliation: Department of Surgery, Beth Israel Hospital, Harvard Medical School, Boston, Massachusetts.
authors.forename: C H
authors.initials: CH
authors.lastname: Lam
authors.forename: G R
authors.initials: GR
authors.lastname: Cosgrove
authors.forename: F W
authors.initials: FW
authors.lastname: Drislane
authors.forename: A
authors.initials: A
authors.lastname: Sotrel
mesh_terms: D000368:Aged; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology*; D003287:Contrast Media; D005682:Gadolinium; D019786:Gadolinium DTPA; D005909:Glioblastoma / Q000175:diagnosis / Q000473:pathology / Q000556:secondary*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000556:secondary*; D009366:Neoplasm Seeding; D009942:Organometallic Compounds; D004369:Pentetic Acid; D013120:Spinal Cord Neoplasms / Q000556:secondary*
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA