Purification and characterization of a thymocyte growth factor. 1. Purification.
A thymocyte growth factor has been purified by gel filtration and reverse-phase hplc from the culture medium of a T-lymphocyte-precursor cell line TC.SC-1/2.0. The purified thymocyte growth factor possesses high growth-stimulating activity and has a relative molecular mass of 20,000, as determined by SDS-PAGE.
Talaev VYu
Research Institute of Epidemiology and Microbiology, Ministry of Health of Russia, Nizhnii Novgorod.
Shuvaeva
T M
TM
Lipkin
V M
VM
Yarilin
A A
AA
Shichkin
V P
VP
D000818:Animals; D002460:Cell Line; D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D006133:Growth Substances / Q000302:isolation & purification*; D036341:Intercellular Signaling Peptides and Proteins; D051379:Mice; D008808:Mice, Inbred CBA; D010455:Peptides / Q000302:isolation & purification*; D013601:T-Lymphocytes / Q000737:chemistry*
D006133:Growth Substances; D036341:Intercellular Signaling Peptides and Proteins; D010455:Peptides; C052275:thymocyte growth peptide