[Catalytic properties of plasmin and the equimolar plasmin-streptokinase complex in their reactions with various substrates and inhibitors].
The interactions of plasmin and plasmin-streptokinase equimolar complex with a number of protein and low-molecular weight substrates as well as protein inhibitors have been examined. It was concluded that the above interactions entail structural changes in the complexes formed, which trigger the activator, increase the rate constants of low molecular weight substrates but create steric hindrances to the interaction with protein substrates and inhibitors.
Aĭsina
R B
RB
Zhitkova
Iu V
IuV
Fedorenko
Ia E
IaE
Kazanskaia
N F
NF
D002364:Caseins / Q000378:metabolism; D002384:Catalysis; D004950:Esterases / Q000378:metabolism; D005337:Fibrin / Q000378:metabolism; D005341:Fibrinolysin / Q000037:antagonists & inhibitors / Q000378:metabolism*; D006801:Humans; D008970:Molecular Weight; D011506:Proteins / Q000378:metabolism*; D013300:Streptokinase / Q000378:metabolism*; D013379:Substrate Specificity
D002364:Caseins; D011506:Proteins; D005337:Fibrin; D004950:Esterases; D013300:Streptokinase; D005341:Fibrinolysin
Kataliticheskie svoĭstva plazmina i ékvimoliarnogo kompleksa plazmin-streptokinaza v reaktsiiakh s razlichnymi substratami i ingibitorami.