Stratification of multiple myeloma according to serum beta 2-microglobulin and serum albumin levels.
In 71 patients with multiple myeloma the authors evaluated the clinical significance and the prognostic relevance of Bataille's stratification system based on serum beta 2-microglobulin and serum albumin levels. This staging system, which classified the patients to low, intermediate and poor risk groups (stages 1-3) showed a rather small prognostic significance, and it stratified our myeloma patients unsatisfactorily. On the basis of the results of our own analyses, we have developed our own modification of a pilot stratification system. We have verified its good clinical applicability and its powerful prognostic prediction. In this study, the good prognostic significance of serum beta 2-microglobulin and albumin levels (with the best cut-off levels of 4.0 mg/l and 35.0 g/l) and a good correlation between both analysed markers were confirmed.
Scudla
V
V
Third Medical Department, Medical Faculty of the Palacký University, Olmouc, CSFR.
Budíková
M
M
Fischerová
E
E
Zadrazil
J
J
Indrák
K
K
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008875:Middle Aged; D009101:Multiple Myeloma / Q000097:blood* / Q000145:classification / Q000401:mortality; D011379:Prognosis; D012709:Serum Albumin / Q000032:analysis*; D015996:Survival Rate; D001613:beta 2-Microglobulin / Q000032:analysis*
D012709:Serum Albumin; D001613:beta 2-Microglobulin