title: Erythroderma, palmoplantar keratoderma and profound failure to thrive in an infant.
abstract: The case is reported of a female infant, who at the age of 3 months developed severe erythroderma, marked hyperkeratosis of the palms and soles and subsequently extreme growth failure and intermittent diarrhoea. Her course was complicated by life-threatening infections but detailed investigation revealed no recognized underlying metabolic or immune abnormality.
authors.affiliation: Department of Dermatology, Hospitals for Sick Children, London, U.K.
authors.forename: M R
authors.initials: MR
authors.lastname: Judge
authors.forename: J P
authors.initials: JP
authors.lastname: Shield
authors.forename: A
authors.initials: A
authors.lastname: Cant
authors.forename: S
authors.initials: S
authors.lastname: Strobel
authors.forename: M
authors.initials: M
authors.lastname: Levin
authors.forename: J
authors.initials: J
authors.lastname: Reiser
authors.forename: J I
authors.initials: JI
authors.lastname: Harper
mesh_terms: D003873:Dermatitis, Exfoliative / Q000150:complications / Q000473:pathology*; D005183:Failure to Thrive / Q000150:complications / Q000473:pathology*; D005260:Female; D006225:Hand / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D015776:Keratoderma, Palmoplantar, Diffuse / Q000150:complications / Q000473:pathology*; D011379:Prognosis; D012867:Skin / Q000473:pathology; D013577:Syndrome