[Elevation of atrial natriuretic factor in alveolo-interstitial lesions of connective tissue diseases].
Plasma levels of the atrial natriuretic factor were prospectively measured in 15 patients suffering from connective tissue disease with alveolar-interstitial lung lesions. The mean level was significantly higher in these patients than in 12 patients without known lung lesions (74.8 +/- 20.7 pg/ml versus 30.8 +/- 12 pg/ml; P less than 0.01) and in 18 healthy subjects (25.4 +/- 12.6 pg/ml). There was no correlation between these levels and lung function tests. Three patients with isolated lymphocytosis in the alveolar lavage fluid had a high level of atrial natriuretic factor.
Oberlin
F
F
Service de Rhumatologie, Hôpital de la Pitié-Salpêtrière, Paris.
Piette
J C
JC
Eugène
L
L
Maistre
G
G
Masson
F
F
Barthelemy
C
C
Camus
J P
JP
D009320:Atrial Natriuretic Factor / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011658:Pulmonary Fibrosis / Q000097:blood* / Q000453:epidemiology / Q000209:etiology; D012216:Rheumatic Diseases / Q000150:complications* / Q000453:epidemiology
D009320:Atrial Natriuretic Factor
Elévation du facteur atrial natriurétique au cours des atteintes alvéolo-interstitielles des connectivites.