Rational design of thromboxane A2 antagonists.
Hamanaka
N
N
Minase Research Institute, Ono Pharmaceutical Co., Ltd., Osaka, Japan.
Seko
T
T
Miyazaki
T
T
Kawasaki
A
A
D001643:Bridged Bicyclo Compounds / Q000737:chemistry / Q000494:pharmacology*; D003198:Computer Simulation; D015195:Drug Design; D005229:Fatty Acids, Monounsaturated / Q000737:chemistry / Q000494:pharmacology*; D005231:Fatty Acids, Unsaturated / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D010974:Platelet Aggregation / Q000187:drug effects; D013329:Structure-Activity Relationship; D013928:Thromboxane A2 / Q000037:antagonists & inhibitors*
D001643:Bridged Bicyclo Compounds; D005229:Fatty Acids, Monounsaturated; D005231:Fatty Acids, Unsaturated; C056566:S 145; C067519:ONO-NT 125; C067520:ONO-NT 126; D013928:Thromboxane A2