title: Increased activity of pyridoxal kinase in tongue in Down's syndrome.
abstract: The concentrations of B6 vitamins, and the activities of pyridoxal kinase, pyridoxamine phosphate oxidase and pyridoxal phosphate phosphatase were measured in tongue. Pyridoxal kinase activity was significantly greater (P less than 0.01) in Down's syndrome subjects compared with controls.
authors.affiliation: Biochemistry Department, Fort Wayne State Developmental Center, Indiana 46835.
authors.forename: S P
authors.initials: SP
authors.lastname: Coburn
authors.forename: J D
authors.initials: JD
authors.lastname: Mahuren
authors.forename: W E
authors.initials: WE
authors.lastname: Schaltenbrand
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004314:Down Syndrome / Q000097:blood / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011731:Pyridoxal Kinase / Q000097:blood*; D011732:Pyridoxal Phosphate / Q000097:blood; D011736:Pyridoxine / Q000008:administration & dosage / Q000378:metabolism*; D014059:Tongue
chemical_list: D011732:Pyridoxal Phosphate; D011731:Pyridoxal Kinase; D011736:Pyridoxine