title: High-resolution magnetic resonance imaging of the interphalangeal joints of the hand.
abstract: High-resolution magnetic resonance imaging (MRI) of the interphalangeal joints of the fingers is being employed to study arthritis. To facilitate this research, a clear understanding of the structures visualisable by MRI is necessary. A gradient echo (GE) sequence was developed that produced good contrast between cartilage and other joint structures. These detailed images, with an in-plane resolution of 200 x 100 microns, enable resolution of three cartilage zones which can be interpreted as a superficial layer at the cartilage/cartilage interface, an intermediate layer and calcified cartilage in contact with bone; these correlate well with known anatomy. Further analysis of the images indicates that although a chemical shift artifact causes changes in the images at the field strength used (0.5 T), it does not cause enough distortion to necessitate suppression of the effect. Furthermore, the only detectable susceptibility artifact at these low field strengths was a loss of signal in bone trabeculae at the bone/cartilage interface. There is clearly potential in the study of the articular structures, in particular cartilage, in detail, using high-resolution MRI.
authors.affiliation: Department of Physics, University of Exeter, UK.
authors.forename: M E
authors.initials: ME
authors.lastname: Fry
authors.forename: R K
authors.initials: RK
authors.lastname: Jacoby
authors.forename: C W
authors.initials: CW
authors.lastname: Hutton
authors.forename: R E
authors.initials: RE
authors.lastname: Ellis
authors.forename: M
authors.initials: M
authors.lastname: Phil
authors.forename: S
authors.initials: S
authors.lastname: Pittard
authors.forename: W
authors.initials: W
authors.lastname: Vennart
mesh_terms: D000328:Adult; D002358:Cartilage, Articular / Q000033:anatomy & histology; D005260:Female; D005384:Finger Joint / Q000033:anatomy & histology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D013933:Thumb / Q000033:anatomy & histology*