title: Interactive effects of sodium zeolite-A and copper in growing swine: growth, and bone and tissue mineral concentrations.
abstract: An experiment was conducted with 64 crossbred pigs to determine the effect of 0 or .50% dietary sodium zeolite-A (NZA) in combination with 0 or 250 ppm supplemental Cu (as CuSO4.5H2O). Pigs were assigned randomly to one of the following four treatments: 1) corn-soybean meal basal (B), 2) B + .50% NZA, 3) B + 250 ppm Cu, or 4) B + .50% NZA + 250 ppm Cu. Each treatment was replicated four times with four pigs per replicate. Average initial weight was 7.5 kg and the experimental period lasted 144 d. Overall rate and efficiency of gain, incidence of gastric ulcers, dressing percentage, carcass weight, percentage of muscling, 10th rib fat, loin eye area, blood urea N, and bone Ca, P, Mn, Fe, Ni, Na, and Al concentrations were not affected by treatment. The addition of 250 ppm Cu increased liver (P less than .01), serum (P less than .06), and bone (P less than .07) Cu concentrations but decreased mean backfat thickness (P less than .09), bone ash percentage (P less than .03) and serum (P less than .09) and bone (P less than .01) Zn concentrations. Sodium zeolite-A increased serum alkaline phosphatase (P less than .04), carcass length (P less than .06), and liver (P less than .02) and bone (P less than .01) Zn content but decreased (P less than .04) serum Ca and serum inorganic P concentrations. Sodium zeolite-A did not protect against liver Cu accumulation or gastric ulceration in growing swine fed 250 ppm supplemental Cu.
authors.affiliation: Louisiana Agricultural Experiment Station, Louisiana State University Agricultural Center, Baton Rouge 70803.
authors.forename: T L
authors.initials: TL
authors.lastname: Ward
authors.forename: K L
authors.initials: KL
authors.lastname: Watkins
authors.forename: L L
authors.initials: LL
authors.lastname: Southern
authors.forename: P G
authors.initials: PG
authors.lastname: Hoyt
authors.forename: D D
authors.initials: DD
authors.lastname: French
mesh_terms: D000273:Adipose Tissue / Q000187:drug effects; D000538:Aluminum Silicates / Q000494:pharmacology*; D000818:Animals; D001842:Bone and Bones / Q000737:chemistry / Q000187:drug effects*; D003300:Copper / Q000494:pharmacology*; D004435:Eating / Q000187:drug effects; D005260:Female; D008099:Liver / Q000737:chemistry; D008297:Male; D008903:Minerals / Q000032:analysis* / Q000097:blood; D011897:Random Allocation; D013552:Swine / Q000254:growth & development*; D015430:Weight Gain / Q000187:drug effects; D017641:Zeolites
chemical_list: D000538:Aluminum Silicates; D008903:Minerals; D017641:Zeolites; D003300:Copper