Inhibitory potencies of fish oil hydroxy fatty acids on cellular lipoxygenases and platelet aggregation.
Vanderhoek
J Y
JY
Department of Biochemistry and Molecular Biology, George Washington University School of Medicine and Health Sciences, Washington, DC 20037.
Schoene
N W
NW
Pham
P P
PP
D000818:Animals; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000378:metabolism; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism; D004281:Docosahexaenoic Acids / Q000097:blood; D015118:Eicosapentaenoic Acid / Q000097:blood; D005227:Fatty Acids / Q000494:pharmacology*; D005395:Fish Oils / Q000494:pharmacology*; D006801:Humans; D006893:Hydroxyeicosatetraenoic Acids / Q000097:blood; D008055:Lipids / Q000097:blood; D008084:Lipoxygenase / Q000097:blood / Q000187:drug effects*; D016859:Lipoxygenase Inhibitors; D009504:Neutrophils / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism; D010974:Platelet Aggregation / Q000187:drug effects*; D051381:Rats; D013929:Thromboxane B2 / Q000097:blood
D001095:Arachidonic Acids; D005227:Fatty Acids; D005395:Fish Oils; D006893:Hydroxyeicosatetraenoic Acids; D008055:Lipids; D016859:Lipoxygenase Inhibitors; D004281:Docosahexaenoic Acids; D016718:Arachidonic Acid; D013929:Thromboxane B2; C025984:15-hydroxy-5,8,11,13-eicosatetraenoic acid; C059528:14-hydroxydocosahexaenoic acid; D015118:Eicosapentaenoic Acid; D008084:Lipoxygenase