title: [Effect of the non-hydrolyzable guanosine triphosphate analogue on dopamine modulation of the calcium current in a snail neuron].
abstract: Voltage-activated calcium current was recorded in isolated neurons of Lymnaea stagnalis under voltage clamp and intracellular dialysis conditions. Calcium current was modulated by non-hydrolyzable guanine nucleotide analogue, guanosine-5'-0-3-thiotriphosphate (GTP gamma S), in a receptor-mediated manner: effect of 100 microM GTP gamma S was recorded at activation of the dopamine receptor. The results obtained permitted suggesting that the effect of dopamine on calcium channels in these neurons is a GTP-dependent one.
authors.forename: V G
authors.initials: VG
authors.lastname: Safronova
authors.forename: N K
authors.initials: NK
authors.lastname: Chemeris
mesh_terms: D000818:Animals; D015220:Calcium Channels / Q000187:drug effects / Q000502:physiology*; D004298:Dopamine / Q000502:physiology*; D016244:Guanosine 5'-O-(3-Thiotriphosphate) / Q000494:pharmacology*; D006868:Hydrolysis; D008195:Lymnaea / Q000187:drug effects*; D009474:Neurons / Q000187:drug effects*
chemical_list: D015220:Calcium Channels; D016244:Guanosine 5'-O-(3-Thiotriphosphate); D004298:Dopamine
vernacular_title: Deĭstvie negidrolizuemogo analoga guanozintrifosfata na moduliatsiiu kal'tsievogo toka dofaminom v neĭrone prudovika.