The effect of cells on biomaterial calcification: experiments with in vivo diffusion chambers.
The results of these in vivo experiments show that bovine pericardium can undergo calcification without direct contact with tissue. It is clear that the direct interaction of cells with implanted samples both promotes and accelerates the process of calcification. Moreover, dietary calcium supplements, calcium chloride and vitamin D can intensify the rate and extent of this process.
Rosanova
I B
IB
Institute of Transplantology and Artificial Organs, Moscow, USSR.
Mischenko
B P
BP
Zaitsev
V V
VV
Vasin
S L
SL
Sevastianov
V I
VI
D000818:Animals; D001672:Biocompatible Materials; D002113:Calcification, Physiologic / Q000187:drug effects; D002118:Calcium / Q000378:metabolism*; D002122:Calcium Chloride / Q000494:pharmacology; D002417:Cattle; D004058:Diffusion; D008855:Microscopy, Electron, Scanning; D010496:Pericardium / Q000502:physiology* / Q000637:transplantation / Q000648:ultrastructure; D011093:Polyethylene Terephthalates; D011817:Rabbits; D014807:Vitamin D / Q000494:pharmacology
D001672:Biocompatible Materials; D011093:Polyethylene Terephthalates; D014807:Vitamin D; D002122:Calcium Chloride; D002118:Calcium