title: A novel subgroup of exogenous avian leukosis virus in chickens.
abstract: An avian leukosis virus with a wide host range belonging to a new subgroup for chickens was isolated from meat-type chicken lines. The virus, of which HPRS-103 strain is the prototype, was of low oncogenicity in chickens but appeared to behave like an exogenous leukosis virus. Neutralizing antibodies to the virus were found in three of five meat-type chicken lines, but not in seven layer lines. The virus and its Rous sarcoma virus pseudotype did not replicate in, or transform, mammalian cells.
authors.affiliation: AFRC Institute for Animal Health, Houghton Laboratory, Huntingdon, Cambridgeshire, U.K.
authors.forename: L N
authors.initials: LN
authors.lastname: Payne
authors.forename: S R
authors.initials: SR
authors.lastname: Brown
authors.forename: N
authors.initials: N
authors.lastname: Bumstead
authors.forename: K
authors.initials: K
authors.lastname: Howes
authors.forename: J A
authors.initials: JA
authors.lastname: Frazier
authors.forename: M E
authors.initials: ME
authors.lastname: Thouless
mesh_terms: D000818:Animals; D000914:Antibodies, Viral; D001354:Avian Leukosis Virus / Q000145:classification* / Q000302:isolation & purification / Q000502:physiology; D001358:Avian Sarcoma Viruses / Q000502:physiology; D015139:Blotting, Southern; D015153:Blotting, Western; D002460:Cell Line; D002642:Chick Embryo; D002645:Chickens / Q000382:microbiology*; D003370:Coturnix / Q000382:microbiology; D004279:DNA, Viral / Q000302:isolation & purification; D004625:Embryo, Nonmammalian; D014709:Vero Cells; D014764:Viral Proteins / Q000302:isolation & purification; D014779:Virus Replication
chemical_list: D000914:Antibodies, Viral; D004279:DNA, Viral; D014764:Viral Proteins