Ion transport inhibition in the medullary thick ascending limb of Henle's loop by cytochrome P450-arachidonic acid metabolites.
Escalante
B
B
Department of Pharmacology, New York Medical College, Valhalla 10595.
Erlij
D
D
Falck
J R
JR
McGiff
J C
JC
D000818:Animals; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000378:metabolism* / Q000494:pharmacology; D002478:Cells, Cultured; D000090762:Cytochrome P-450 CYP2J2; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D003864:Depression, Chemical; D005665:Furosemide / Q000494:pharmacology; D015640:Ion Channel Gating / Q000187:drug effects*; D008138:Loop of Henle / Q000187:drug effects* / Q000378:metabolism; D010042:Ouabain / Q000494:pharmacology; D010101:Oxygen Consumption / Q000187:drug effects; D010105:Oxygenases / Q000378:metabolism*; D011817:Rabbits; D012413:Rubidium / Q000378:metabolism; D000254:Sodium-Potassium-Exchanging ATPase / Q000037:antagonists & inhibitors
D001095:Arachidonic Acids; D016718:Arachidonic Acid; D010042:Ouabain; C067517:20-carboxyarachidonic acid; D005665:Furosemide; D003577:Cytochrome P-450 Enzyme System; D010105:Oxygenases; D000090762:Cytochrome P-450 CYP2J2; D000254:Sodium-Potassium-Exchanging ATPase; D012413:Rubidium