A case of trisomy 21 with holoprosencephaly: the fifth case.
A case of trisomy 21 with holoprosencephaly, the fifth case in the literature, is described. The patient also had extracephalic malformations frequently associated with Down syndrome. The possibility of a causal relationship between trisomy 21 and holoprosencephaly is discussed.
Hamada
H
H
Department of Obstetrics and Gynecology, University of Tsukuba, Ibaraki, Japan.
Arinami
T
T
Koresawa
M
M
Kubo
T
T
Hamaguchi
H
H
Iwasaki
H
H
D000015:Abnormalities, Multiple / Q000235:genetics*; D044466:Asian People / Q000235:genetics; D004314:Down Syndrome / Q000235:genetics*; D005260:Female; D016142:Holoprosencephaly / Q000235:genetics*; D006801:Humans; D007564:Japan; D011247:Pregnancy