[Active rheumatoid arthritis: effect of dietary supplementation with omega-3 oils. A controlled double-blind trial].
We evaluated the effect of dietary supplementation with eicosapentaenoic acid in 8 patients with active rheumatoid arthritis. An appropriate placebo was given in a randomized double blind fashion to 8 control subjects. After 12 weeks of therapy a significant improvement in prehensile function was detected in patients receiving active treatment, other clinical parameters remaining unchanged. No significant side effects were detected. A larger trial may help define a possible therapeutic role for omega-3 fatty acids in patients with rheumatoid arthritis.
Astorga
G
G
Departamento de Medicina (Sección Reumatología), Facultad de Medicina, Universidad de Chile, Santiago.
Cubillos
A
A
Masson
L
L
Silva
J J
JJ
D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000178:diet therapy*; D004042:Dietary Fats, Unsaturated / Q000627:therapeutic use*; D015525:Fatty Acids, Omega-3 / Q000627:therapeutic use*; D005260:Female; D005395:Fish Oils / Q000627:therapeutic use*; D006225:Hand / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009068:Movement
D004042:Dietary Fats, Unsaturated; D015525:Fatty Acids, Omega-3; D005395:Fish Oils
Artritis reumatóidea activa: efecto de la suplementación dietética con aceites omega 3. Estudio doble ciego controlado.