[Growth factors and oncogenes in brain tumors: the model of glioblastoma and medulloblastoma].
Glioblastomas and medulloblastomas are models for studying the implication of growth factors and oncogenes in tumor development. Amplification and/or hyperexpression of oncogenes result in products that may mimic growth factors and/or their receptors; cells may demonstrate autocrine and/or paracrine activity. Prognostic implications of such findings are suggested.
Frappaz
D
D
Laboratoire de culture cellulaire à moyen terme, faculté de médecine de St-Etienne, St-Etienne, France.
Elian
J C
JC
Brunon
J
J
Freycon
F
F
D001932:Brain Neoplasms / Q000503:physiopathology*; D002460:Cell Line; D002648:Child; D005729:Ganglioneuroma / Q000503:physiopathology*; D006133:Growth Substances / Q000502:physiology*; D006801:Humans; D008527:Medulloblastoma / Q000503:physiopathology*; D009857:Oncogenes / Q000502:physiology*
D006133:Growth Substances
Facteurs de croissance et oncogènes dans les tumeurs cérébrales: le modèle du glioblastome et du médulloblastome.