title: [Evaluation of clinical effectiveness of colchicine in the treatment of chronic active hepatitis with transformation to liver cirrhosis].
abstract: 12 patients with viral chronic active hepatitis, confirmed clinically and histopathologically, were treated with colchicine in doses 1 mg orally, daily. After 20 months, on average, therapy only 2 patients presented the clinical and histopathological improvement of liver disease. In group of remain patients we observed deterioration of liver function and progression of the disease.
authors.affiliation: Katedra i Klinika Chorób Zakaźnych AM, Wrocławiu.
authors.forename: K
authors.initials: K
authors.lastname: Simon
authors.forename: A
authors.initials: A
authors.lastname: Gładysz
authors.forename: M
authors.initials: M
authors.lastname: Zalewska
authors.forename: A
authors.initials: A
authors.lastname: Machaj
mesh_terms: D000284:Administration, Oral; D000328:Adult; D015415:Biomarkers; D003078:Colchicine / Q000008:administration & dosage*; D005260:Female; D006509:Hepatitis B / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006513:Hepatitis B e Antigens / Q000032:analysis; D006521:Hepatitis, Chronic / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D008103:Liver Cirrhosis / Q000209:etiology* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D013997:Time Factors
chemical_list: D015415:Biomarkers; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens; D003078:Colchicine
vernacular_title: Ocena klinicznej skuteczności kolchicyny w leczeniu przewlekłego czynnego wirusowego zapalenia watroby przechodzacego w marskość.