title: [Anticardiolipin antibodies and primary antiphospholipid syndrome of the central nervous system: report of 10 clinical cases].
abstract: An association between anti-phospholipid antibodies and different disorders of the central nervous system has been described recently. We used an ELISA technique and detected anti-cardiolipin antibodies of the IgG or IgM variety in a series of 10 patients: 4 had occlusive stroke, 2 brain hemorrhage, 2 chorea, 1 a Sneddon syndrome and 1 vascular cephalea. The diagnosis of primary anti-phospholipid syndrome was suggested after ruling out systemic lupus in all patients.
authors.affiliation: Servicio de Neurología, Hospital Dr Sótero del Río, Santiago, Chile.
authors.forename: J L
authors.initials: JL
authors.lastname: Córdova
authors.forename: O
authors.initials: O
authors.lastname: Neira
authors.forename: P
authors.initials: P
authors.lastname: Abumohor
authors.forename: S
authors.initials: S
authors.lastname: Palma
authors.forename: F
authors.initials: F
authors.lastname: Vergara
authors.forename: L
authors.initials: L
authors.lastname: Guzmán
mesh_terms: D000328:Adult; D000368:Aged; D017153:Antibodies, Anticardiolipin / Q000032:analysis* / Q000378:metabolism; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D002544:Cerebral Infarction / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D014057:Tomography, X-Ray Computed
chemical_list: D017153:Antibodies, Anticardiolipin; D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: Anticuerpos anticardiolipinas y síndrome antifosfolípidos primario del sistema nervioso central: comunicación de 10 casos clínicos.