title: Inhibition of I-A expression in rat peritoneal macrophages due to T-suppressor cells induced by Cryptococcus neoformans.
abstract: The expression of I-A antigen in rat peritoneal cells was significantly reduced during infection with Cryptococcus neoformans. When studying the in vitro action of T-suppressor cells induced by the fungus, or a soluble factor from the T-suppressor cells, a significant decrease in I-A expression by the peritoneal cells was observed. This expression was partially restored by indomethacin.
authors.affiliation: Departamento de Bioquimica Clinica, Facultad de Ciencias Quimicas, Universidad Nacional de Cordoba, Argentina.
authors.forename: D T
authors.initials: DT
authors.lastname: Masih
authors.forename: C E
authors.initials: CE
authors.lastname: Sotomayor
authors.forename: L A
authors.initials: LA
authors.lastname: Cervi
authors.forename: C M
authors.initials: CM
authors.lastname: Riera
authors.forename: H R
authors.initials: HR
authors.lastname: Rubinstein
mesh_terms: D000818:Animals; D003453:Cryptococcosis / Q000276:immunology*; D003455:Cryptococcus neoformans / Q000276:immunology*; D000949:Histocompatibility Antigens Class II / Q000037:antagonists & inhibitors* / Q000096:biosynthesis; D007213:Indomethacin / Q000494:pharmacology; D008264:Macrophages / Q000276:immunology*; D010529:Peritoneal Cavity / Q000166:cytology; D051381:Rats; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*
chemical_list: D000949:Histocompatibility Antigens Class II; D007213:Indomethacin