title: Neuro-ophthalmic complications of interleukin 2 therapy.
abstract: We describe three patients who experienced several types of visual problems while receiving interleukin 2 therapy for melanoma or lymphoma. Their symptoms included diplopia, binocular negative scotomata, scintillating scotomata, and palinopsia. All symptoms eventually resolved following discontinuation of therapy. It appears that focal neurologic deficits that affect the visual system may complicate interleukin 2 administration.
authors.affiliation: Doheny Eye Institute, University of Southern California, Los Angeles 90033.
authors.forename: D I
authors.initials: DI
authors.lastname: Friedman
authors.forename: E H
authors.initials: EH
authors.lastname: Hu
authors.forename: A A
authors.initials: AA
authors.lastname: Sadun
mesh_terms: D000328:Adult; D004172:Diplopia / Q000139:chemically induced; D005260:Female; D006801:Humans; D007376:Interleukin-2 / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012607:Scotoma / Q000139:chemically induced; D014786:Vision Disorders / Q000139:chemically induced*
chemical_list: D007376:Interleukin-2