Clinical-instrumental evaluation of the effects of mesoglycan sulphate in chronic vascular encephalopathy.
15 patients with chronic cerebrovascular disease were studied using carotid Doppler and B-mode echography, transcranial Doppler, EEG and clinical evaluation before and 3 and 6 months after treatment with mesoglycan sulphate at doses of 96 mg/day per os. A subjective improvement was reported by 7 out of 15 patients while no significant variations in Doppler, TCD, echographic and EEG data were observed. During treatment no side effects or laboratory abnormalities were found.
Orlandi
G
G
Unit of Clinical Neurophysiology, Dpt. of Neurology, University of Fisa, Italy.
Viapiano
F
F
Massetani
R
R
Ferrari
M
M
Murri
L
L
D000368:Aged; D000369:Aged, 80 and over; D002561:Cerebrovascular Disorders / Q000188:drug therapy*; D002908:Chronic Disease; D005260:Female; D006025:Glycosaminoglycans / Q000627:therapeutic use*; D006801:Humans; D008297:Male
D006025:Glycosaminoglycans; C040617:mesoglycan