Ichthyosis bullosa of Siemens responds well to low-dosage oral retinoids.
Two patients with ichthyosis bullosa of Siemens (IBS) and one patient with bullous ichthyosiform erythroderma of Brocq (BIE) were treated with etretinate. Two additional patients with IBS received acitretin. All the patients had a marked improvement when on retinoids and the maintenance dose required was for IBS 10-25 mg per day. The patient with BIE was on a maintenance dose of 40-60 mg per day.
Steijlen
P M
PM
Department of Dermatology, University of Nijmegen, The Netherlands.
van Dooren-Greebe
R J
RJ
Happle
R
R
Van de Kerkhof
P C
PC
D017255:Acitretin; D000328:Adult; D004334:Drug Administration Schedule; D005050:Etretinate / Q000008:administration & dosage; D005260:Female; D006225:Hand; D006801:Humans; D016113:Ichthyosiform Erythroderma, Congenital / Q000188:drug therapy* / Q000473:pathology; D007866:Leg; D008297:Male; D008875:Middle Aged; D012176:Retinoids / Q000627:therapeutic use*; D012867:Skin / Q000473:pathology; D014212:Tretinoin / Q000008:administration & dosage / Q000031:analogs & derivatives
D012176:Retinoids; D014212:Tretinoin; D005050:Etretinate; D017255:Acitretin