title: [Disorders of T-cell immunity in patients with eczema, atopic dermatitis and psoriasis].
abstract: It is shown that patients suffering from eczema, atopic dermatitis and psoriasis demonstrate immunologic shifts related to genetic predisposition to allergic (atopic and autoimmune) responses, specific skin responses, clinical features of dermatoses, reactivity of the affected connective tissue. Immune defects of the above patients suggest a drop in T-lymphocyte count and T-suppressor dysfunction, i.e. T-cell immunodeficiency. This indicates possible benefit of pharmacological immunomodulators scheduled on the basis of pathogenetic characteristics of each variant of dermatosis and of dermal inflammation.
authors.forename: I E
authors.initials: IE
authors.lastname: Khazizov
mesh_terms: D003876:Dermatitis, Atopic / Q000276:immunology*; D004485:Eczema / Q000276:immunology*; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis; D007958:Leukocyte Count; D011565:Psoriasis / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
chemical_list: D007136:Immunoglobulins; D007073:Immunoglobulin E
vernacular_title: Narusheniia T-kletochnogo immuniteta u bol'nykh ékzemoĭ, atopicheskim dermatitom, psoriazom.