title: [Disseminated intraperitoneal trophoblast tissue after laparoscopic treatment of extrauterine pregnancy].
abstract: We report on the atypical course of a 31-year old primigravida, who underwent conservative treatment for a tubal pregnancy. After confirmation of the diagnosis by means of laparoscopy, a linear salpingotomy and removal of the products of gestation were performed through the laparoscope. Routine measurements of the serum HCG levels postoperatively showed, after a short period of decreasing HCG levels, a new rapid increase of HCG values. At relaparoscopy, evidence for an intraperitoneal dissemination of trophoblastic tissue was found and confirmed by histology. After treatment with 20 mg methotrexate q.i.d. per os for 5 days, HCG levels returned to normal within a short time. Apart from a minor degree of an aphthosal stomatitis, the patient did not experience any major side effects from the treatment.
authors.affiliation: Universitätsfrauenklinik Erlangen.
authors.forename: E
authors.initials: E
authors.lastname: Beck
authors.forename: E
authors.initials: E
authors.lastname: Siebzehnrübl
authors.forename: W
authors.initials: W
authors.lastname: Jäger
authors.forename: L
authors.initials: L
authors.lastname: Wildt
authors.forename: N
authors.initials: N
authors.lastname: Lang
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood; D001706:Biopsy; D006063:Chorionic Gonadotropin / Q000097:blood; D002828:Choristoma / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D010535:Laparoscopy; D002955:Leucovorin / Q000008:administration & dosage; D008727:Methotrexate / Q000008:administration & dosage; D009366:Neoplasm Seeding; D010534:Peritoneal Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D010537:Peritoneum / Q000473:pathology; D011183:Postoperative Complications / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery*; D011247:Pregnancy; D011274:Pregnancy, Tubal / Q000473:pathology* / Q000601:surgery*; D012489:Salpingostomy; D014327:Trophoblasts
chemical_list: D014408:Biomarkers, Tumor; D006063:Chorionic Gonadotropin; D002955:Leucovorin; D008727:Methotrexate
vernacular_title: Disseminierte intraperitoneale Trophoblast-Aussaat nach laparoskopisch behandelter Extrauteringravidität.