[New approaches to the treatment of mycobacterioses of the lungs].
The paper deals with improvement of pulmonary mycobacterioses treatment. In the preliminary experiments with the use of an experimental model, 32 regimens of M. avium mycobacteriosis treatment were tested on 872 white mice and the most efficient one was chosen, which comprised a combination of kanamycin-ethambutol-thionamide coupled with sulfadimethoxine and thymalin courses. The clinical course and results of treatment of 43 patients (23 of the main and 20 of the control group) with fibro-cavernous pulmonary mycobacteriosis were studied. Employment of the new treatment regimen significantly enhanced its efficiency--the incidence of bacillary excretion cessation increased from 30 to 82.6%.
Aleksandrova
A E
AE
Vasil'ev
A V
AV
Lozovskaia
M E
ME
D000995:Antitubercular Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
D000995:Antitubercular Agents
Novye podkhody k lecheniiu mikobakteriozov legkikh.