[The fatty acid spectrum in the serum of mothers and infants after premature delivery].
Using the method of gas chromatography on a Carlo Erba 2531 apparatus in Base's modification, the authors identified serum fatty acids of mothers (n = 23) and premature infants (17 girls and 6 boys). The mean birth weight was 2224.3 (800-2650 g), the mean gestation age 34 weeks (28-37 weeks). The fatty acid levels were compared with fatty acid levels of control mothers (n = 7) and control healthy neonates born at term (n = 15). Individual fatty acids were expressed as the ratio in the total volume of fatty acids (100%). The neonates and their mothers were divided into three groups. The most numerous group (n = 12) are mothers who lost the amniotic fluid prematurely (6 hours-12 days), mothers under the influence of Partusisten (n = 10); the third group is formed by mothers treated with ATB (n = 8). In these groups the authors assessed, as compared with controls, the rise of the saturated fatty acid ratio, in particular short-chain fatty acids. The greatest increase was recorded in mothers and children under the influence of Partusisten. The ratio of mono- and polyunsaturated n-6 fatty acids was not altered in the infants, there was, however, a marked reduction of the n-3 fatty acid ratio which are known to play an important role in the regulation of immune responses and to have an anti-inflammatory effect; they are also important for the development of the CNS and retina.(ABSTRACT TRUNCATED AT 250 WORDS)
Mydlilová
A
A
Dĕtská klinika katedry pediatrie Institutu pro dalsí vzdĕlávání lékarů a farmaceutů, Praha.
Mourek
J
J
Base
J
J
Smídová
L
L
Tomásová
H
H
Dvorák
M
M
D005227:Fatty Acids / Q000097:blood*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000097:blood*; D008297:Male; D007752:Obstetric Labor, Premature / Q000097:blood*; D011247:Pregnancy
D005227:Fatty Acids
Spektrum mastných kyselin v séru matek a dĕtí po predcasném porodu.