title: [Soluble elastin and antibody formation].
abstract: In the present study, we have obtained antibodies in rabbits to peptides prepared by digestion of elastin with either oxalic acid or phosphoric acid. By Elisa assay, we have shown the lowest production of antibodies against elastin-derived peptides prepared by digestion of N-elastin with phosphoric acid. We have found a strong cross-reactivity between antibodies obtained to peptides prepared by different digestion of insoluble elastin from bovine ligamentum nuchae or aorta and these antigens. A less pronounced cross-reactivity was observed in case of elastin-derived peptides from porcine aorta.
authors.affiliation: Ustav biochemie, LF UK, Hradec Králové.
authors.forename: A
authors.initials: A
authors.lastname: Stoklasová
authors.forename: Z
authors.initials: Z
authors.lastname: Randová
authors.forename: J
authors.initials: J
authors.lastname: Wimmerová
authors.forename: M
authors.initials: M
authors.lastname: Ledvina
mesh_terms: D000818:Animals; D000917:Antibody Formation; D003429:Cross Reactions; D004549:Elastin / Q000276:immunology*; D006801:Humans; D011817:Rabbits; D012995:Solubility
chemical_list: D004549:Elastin
vernacular_title: Rozpustný elastin a tvorba protilátek.