Acne vulgaris. Pathogenesis and treatment.
Acne vulgaris is a multifactorial disease involving abnormalities in follicular keratinization, sebum production, proliferation of Propionibacterium acnes, and inflammation. Treatment is directed toward reversing these underlying pathogenic factors. Therapeutic options include topical comedolytics, topical and systemic antibiotics, hormonal manipulations, and oral retinoids.
Winston
M H
MH
Department of Dermatology, State University of New York Health Science Center, Brooklyn.
Shalita
A R
AR
D000152:Acne Vulgaris / Q000145:classification / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001585:Benzoyl Peroxide / Q000627:therapeutic use; D006728:Hormones / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D014212:Tretinoin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D006728:Hormones; D014212:Tretinoin; D001585:Benzoyl Peroxide