Mos oncogene expression in human ovarian tumors.
The expression of the mos proto-oncogene was investigated in frozen sections from 15 ovarian adenocarcinomas, 1 seminoma, 1 immature teratoma and 2 benign stromal tumors by in situ RNA/RNA hybridization with a [35S] labeled mos probe. The presence of mos transcripts was detected in one germ cell tumor and three ovarian carcinomas. The putative role of the mos proto-oncogene activation is discussed.
Xerri
L
L
Laboratoire d'Anatomie pathologique, Faculté de Médecine de Marseille, France.
Charpin
C
C
Hassoun
J
J
Birnbaum
D
D
Delapeyriere
O
O
D000230:Adenocarcinoma / Q000235:genetics* / Q000473:pathology; D000368:Aged; D004407:Dysgerminoma / Q000235:genetics / Q000473:pathology; D005260:Female; D015870:Gene Expression; D016258:Genes, mos; D006801:Humans; D009361:Neoplasm Invasiveness; D010051:Ovarian Neoplasms / Q000235:genetics* / Q000473:pathology; D010053:Ovary / Q000166:cytology / Q000502:physiology; D011505:Protein-Tyrosine Kinases / Q000032:analysis; D000090063:Proto-Oncogene Mas; D011518:Proto-Oncogene Proteins / Q000032:analysis; D017231:Proto-Oncogene Proteins c-mos; D012334:RNA, Neoplasm / Q000032:analysis / Q000235:genetics; D013724:Teratoma / Q000235:genetics / Q000473:pathology; D014158:Transcription, Genetic
C000715470:MAS1 protein, human; D000090063:Proto-Oncogene Mas; D011518:Proto-Oncogene Proteins; D012334:RNA, Neoplasm; D011505:Protein-Tyrosine Kinases; D017231:Proto-Oncogene Proteins c-mos