Antibody to human T-lymphotropic virus in a patient with Guillain-Barré syndrome (case report)
Serum sample obtained from a male, 12 year old patient suffering from Guillain-Barré syndrome (GBS) was positive for human T-lymphotropic virus (HTLV-I) antibody by the enzyme-linked immunosorbent assay (ELISA) and the Western Blot analysis (WB). Attempts to isolate enteroviruses (including poliovirus) from faecal material in both tissue culture and suckling mice were unsuccessful; in addition, acute and convalescent paired serum samples did not show any evidence of recent poliovirus infection when tested against the three serotypes. Specific tests for detection of Epstein-Barr virus infection were not performed; however, the Paul-Bunnel test yielded negative results. ELISA for detection of anti-cytomegalovirus IgM was also negative. The concomitant occurrence of either adult T cell leukemia (ATL) or lymphoma was not recorded in this case.
Nakauchi
C M
CM
Seção de Vírus do Instituto Evandro Chagas, Fundação Nacional de Saúde, Belém, Pará, Brazil.
Linhares
A C
AC
Gomes
M L
ML
Maruyama
K
K
Kanzaki
L I
LI
Azevedo
V N
VN
D015153:Blotting, Western; D002648:Child; D004797:Enzyme-Linked Immunosorbent Assay; D015481:HTLV-I Antibodies / Q000032:analysis*; D006801:Humans; D008297:Male; D011129:Polyradiculoneuropathy / Q000276:immunology*
D015481:HTLV-I Antibodies