Bilateral optic neuritis following bacille Calmette-Guérin (BCG) vaccination.
A 12-year-old PPD-negative girl developed bilateral optic neuritis with decreasing visual acuity 5 days after bacille Calmette-Guérin (BCG) vaccination. Laboratory findings and computerized tomography scan of brain and orbit were negative. Cerebrospinal fluid study revealed 62 leukocytes (92% lymphocytes) per cubic millimeter and a protein level of 33 mg/dl. The patient was treated with systemic steroids. The vision returned to normal in 4 weeks and the disc edema resolved in 6 weeks without residual deficit. The complications of BCG are discussed.
Yen
M Y
MY
Department of Ophthalmology, Veterans General Hospital, Taipei, Taiwan, R.O.C.
Liu
J H
JH
D001500:BCG Vaccine / Q000009:adverse effects*; D002648:Child; D003907:Dexamethasone / Q000627:therapeutic use; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D007958:Leukocyte Count; D009902:Optic Neuritis / Q000188:drug therapy / Q000209:etiology*; D012882:Skin Tests; D014376:Tuberculosis / Q000517:prevention & control; D015348:Vision, Binocular; D014792:Visual Acuity
D001500:BCG Vaccine; D003907:Dexamethasone