[Characterization of nucleolar organizers in carcinomatous mammmary lesions].
An argyrophil stain for nucleolar organizer regions (NORs) has been applied to paraffin sections of 24 malignant and 3 benign breast tumors. It was found that the total number of Ag-NORs in malignant breast lesions (3.66) significantly exceeded those in benign lesions (1.65). Relationship between this index and some clinical parameters was studied. A positive correlation between NORs and histological grading and prognostic was found.
Kharrat
A
A
Institut Salah Azaïez, Bab-Saâdoun, Tunis.
Krichen
H
H
Tabbene
F
F
Sellami
M
M
D000328:Adult; D014408:Biomarkers, Tumor; D001943:Breast Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D008940:Mitotic Index; D009367:Neoplasm Staging; D009697:Nucleolus Organizer Region / Q000473:pathology*; D011379:Prognosis; D015996:Survival Rate; D014416:Tunisia / Q000453:epidemiology
D014408:Biomarkers, Tumor
Caractérisation des organisateurs nucléolaires dans les lésions carcinomateuses mammaires.