title: [Metaphyseal and diaphyseal fractures of the femur resulting in growth inequality in children under 3 years of age].
abstract: The authors clinically and radiographically review 42 of 53 children between the ages of 5 months and 3 years treated by closed means from 1983 to 1987 for femoral fracture (average follow-up, 4 years). Evaluation of a large number of patients in this particular age group offers several advantages: a) it regards a phase of evolution in which the modalities of growth do not affect in any significant way the metabolic balance of the growth plate chondrocyte, as occurs in periods of rapid growth. This makes the sample group statistically homogeneous; b) it eliminates the age variable in the search for the factors which may contribute to limb-length discrepancy. The importance of the following factors was statistically analyzed: location, type, and initial displacement of the fracture, accuracy of reduction, and characteristics of the traumatic event. There was a significant correlation between a large degree of limb lengthening and further reduction or corrective procedures under general anesthesia. Overlapping reduction and limb shortening were also closely related. A highly significant correlation was also found between limb lengthening exceeding 15 mm. (range, 15-22 mm.) and the time of day at which the trauma occurred (9-10 pm). The results of treatment suggest the need for a reevaluation, using recently gained knowledge, of Lacroix's theory of the pathogenesis of this disorder as well as the need to examine more thoroughly, with further clinical and experimental studies, the hormonal changes following the trauma.
authors.affiliation: Ospedale Pediatrico Bambino Gesù, Istituto di Ricovero e Cura a Carattere Scientifico, Roma.
authors.forename: V
authors.initials: V
authors.lastname: Guzzanti
authors.forename: A
authors.initials: A
authors.lastname: Di Lazzaro
authors.forename: F
authors.initials: F
authors.lastname: Falciglia
mesh_terms: D002675:Child, Preschool; D005260:Female; D005264:Femoral Fractures / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000601:surgery; D005269:Femur / Q000000981:diagnostic imaging / Q000254:growth & development* / Q000601:surgery; D006801:Humans; D007223:Infant; D007870:Leg Length Inequality / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery; D008297:Male; D010027:Osteotomy; D011859:Radiography
vernacular_title: L'esito in dismetria delle fratture metafisarie e diafisarie del femore in bambini fino ai 3 anni di età.