title: Effect of MAP2, MAP2c, and tau on kinesin-dependent microtubule motility.
abstract: By making use of DIC video microscopy to monitor microtubule motility we have studied the effect of several MAPs (MAP2, MAP2c, tau) on microtubule-kinesin interactions and microtubule gliding. Of the three MAPs tested, MAP2 interferes most strongly with kinesin-dependent microtubule motility.
authors.affiliation: Max-Planck-Unit for Structural Molecular Biology, Hamburg, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Heins
authors.forename: Y H
authors.initials: YH
authors.lastname: Song
authors.forename: H
authors.initials: H
authors.lastname: Wille
authors.forename: E
authors.initials: E
authors.lastname: Mandelkow
authors.forename: E M
authors.initials: EM
authors.lastname: Mandelkow
mesh_terms: D000251:Adenosine Triphosphatases / Q000502:physiology*; D000818:Animals; D001692:Biological Transport; D016547:Kinesins; D008869:Microtubule-Associated Proteins; D008870:Microtubules / Q000502:physiology*; D010784:Photomicrography; D013552:Swine; D014743:Videotape Recording; D016875:tau Proteins
chemical_list: D008869:Microtubule-Associated Proteins; D016875:tau Proteins; D000251:Adenosine Triphosphatases; D016547:Kinesins