title: Alzheimer's disease in Down's syndrome with SPECT.
abstract: Alzheimer's disease often occurs in patients with Down's syndrome. SPECT scanning with I-123 IMP and Tc-99m HMPAO identifies decreased cerebral perfusion and metabolism in these patients at lower cost. In this case, SPECT scanning revealed changes in Alzheimer's disease in a Down's syndrome patient.
authors.affiliation: Division of Neurology, Allentown Hospital-Lehigh Valley Hospital Center, Pennsylvania.
authors.forename: A D
authors.initials: AD
authors.lastname: Rae-Grant
authors.forename: P J
authors.initials: PJ
authors.lastname: Barbour
authors.forename: P
authors.initials: P
authors.lastname: Sirotta
authors.forename: P
authors.initials: P
authors.lastname: Gross
mesh_terms: D000544:Alzheimer Disease / Q000150:complications / Q000000981:diagnostic imaging*; D000662:Amphetamines; D001921:Brain / Q000000981:diagnostic imaging*; D004314:Down Syndrome / Q000150:complications / Q000000981:diagnostic imaging*; D006801:Humans; D007457:Iodine Radioisotopes; D020367:Iofetamine; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D000662:Amphetamines; D007457:Iodine Radioisotopes; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D020367:Iofetamine