title: [Present possibilities of serological detection of the early phase of the disease caused by Toxoplasma gondii].
abstract: The author described the estimation of toxoplasmic antibodies by the method of reverse enzyme immunoanalysis (IgM-ELISA) in 476 sera. The results of IgM-ELISA were compared with the complement fixation reaction (CFR) and indirect fluorescent reaction IgM-ELISA. Of 217 sera which were IgM-NFR positive 115 were positive in IgM-ELISA. In clinically confirmed acute toxoplasmosis high absorbance values of IgM-ELISA were recorded and during repeated examination a dynamic drop of antibodies was observed. The author discusses the importance of IgM-ELISA for the differentiation of acute and chronic stages of toxoplasmosis and draw attention to false IgM-NFR positivity in the sera they examined.
authors.affiliation: Ustav lékarské mikrobiologie 2. lékarské fakulty UK, Praha-Motol.
authors.forename: J
authors.initials: J
authors.lastname: Kawaciuková
authors.forename: K
authors.initials: K
authors.lastname: Dvoráková
authors.forename: V
authors.initials: V
authors.lastname: Potuzník
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis*; D003168:Complement Fixation Tests; D004797:Enzyme-Linked Immunosorbent Assay; D005455:Fluorescent Antibody Technique; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D014122:Toxoplasma / Q000276:immunology; D014123:Toxoplasmosis / Q000175:diagnosis*
chemical_list: D000913:Antibodies, Protozoan; D007075:Immunoglobulin M
vernacular_title: Soucasné moznosti sérologického pråkazu casné fáze onemocnĕní vyvolaného Toxoplasma gondii.