Brain synthesis and cerebrovascular action of cytochrome P-450/monooxygenase metabolites of arachidonic acid.
Ellis
E F
EF
Department of Pharmacology and Toxicology, Medical College of Virginia, Richmond 23298.
Amruthesh
S C
SC
Police
R J
RJ
Yancey
L M
LM
D015126:8,11,14-Eicosatrienoic Acid / Q000031:analogs & derivatives* / Q000037:antagonists & inhibitors / Q000378:metabolism / Q000494:pharmacology; D000818:Animals; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000378:metabolism*; D001923:Brain Chemistry; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D000090762:Cytochrome P-450 CYP2J2; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D005609:Free Radicals; D007213:Indomethacin / Q000494:pharmacology; D051379:Mice; D010100:Oxygen / Q000378:metabolism; D010105:Oxygenases / Q000378:metabolism*; D011453:Prostaglandins / Q000096:biosynthesis; D014664:Vasodilation / Q000187:drug effects
D001095:Arachidonic Acids; D005609:Free Radicals; D011453:Prostaglandins; D016718:Arachidonic Acid; C046783:11,12-epoxy-5,8,14-eicosatrienoic acid; C040776:5,6-epoxy-8,11,14-eicosatrienoic acid; C050715:8,9-epoxyeicosatrienoic acid; C046782:14,15-epoxy-5,8,11-eicosatrienoic acid; D003577:Cytochrome P-450 Enzyme System; D010105:Oxygenases; D000090762:Cytochrome P-450 CYP2J2; D015126:8,11,14-Eicosatrienoic Acid; D010100:Oxygen; D007213:Indomethacin