Transformation mapping of the regulatory elements of the ecdysone-inducible P1 gene of Drosophila melanogaster.
The transcription of the P1 gene is induced by 20-hydroxyecdysone in fat bodies of third-instar larvae. Germ line transformation showed that sequences between -138 to +276 contain elements required for a qualitatively correct developmental and hormonal regulation of P1 transcription. Sequences from -138 to -68 are essential for this expression.
Maschat
F
F
Institut Jacques-Monod, Centre National de la Recherche Scientifique, Paris, France.
Dubertret
M L
ML
Lepesant
J A
JA
D000818:Animals; D001483:Base Sequence; D015152:Blotting, Northern; D004247:DNA / Q000235:genetics / Q000302:isolation & purification; D004331:Drosophila melanogaster / Q000187:drug effects / Q000235:genetics*; D004441:Ecdysterone / Q000494:pharmacology*; D004926:Escherichia coli / Q000235:genetics; D005091:Exons; D007814:Larva; D008969:Molecular Sequence Data; D012045:Regulatory Sequences, Nucleic Acid; D015183:Restriction Mapping; D012689:Sequence Homology, Nucleic Acid; D013539:Simian virus 40 / Q000235:genetics; D014158:Transcription, Genetic
D004441:Ecdysterone; D004247:DNA