title: [Evaluation in experimental animals of a mathematical model of foreseeing variations in values of stable glycosylated hemoglobin].
abstract: Assay of glycosylated hemoglobin provides reliable information on metabolic control in diabetes mellitus over a period of about 90 days. This is why it is currently used as a parameter of blood glucose control in diabetic patients. However, at present little is known about the kinetics of stable glycosylated hemoglobin variations as a result of circadian changes in blood glucose level. The authors describe a mathematical model which allows to foresee glycosylated hemoglobin variability as a result of alterations of blood glucose equilibrium.
authors.affiliation: Istituto Nazionale di Riposo e Cura per Anziani.
authors.forename: E
authors.initials: E
authors.lastname: Del Nero
authors.forename: G
authors.initials: G
authors.lastname: Carta
authors.forename: L
authors.initials: L
authors.lastname: Granata
authors.forename: E
authors.initials: E
authors.lastname: De Lorenzi
authors.forename: A
authors.initials: A
authors.lastname: Cavagnaro
authors.forename: F
authors.initials: F
authors.lastname: Podestà
authors.forename: M P
authors.initials: MP
authors.lastname: Barbieri
authors.forename: M A
authors.initials: MA
authors.lastname: Del Nero
authors.forename: A
authors.initials: A
authors.lastname: Brizzolara
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D002940:Circadian Rhythm; D005260:Female; D006442:Glycated Hemoglobin / Q000592:standards*; D008297:Male; D008954:Models, Biological; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin
vernacular_title: Valutazione sull'animale da esperimento di un modello matematico per la previsione delle variazioni dei valori di emoglobina glicosilata stabile.