Systemic circulation with high frequency blood flow--analysis from neurophysiological point of view.
The vibrating electromagnetically driven univalved artificial heart, which provided more than 10 1/min at 10 Hz/sec. vibration, was developed in our team. This vibrating electromagnetic pump (VEMP) produced the original flow pattern compared with the flow pattern of the natural heart, so that circulatory regulatory system during maintain the circulation with VEMP must be investigated before the clinical application. In order to assess the effect of high frequency blood flow produced by the VEMP from the neurophysiological point of view, power spectral analysis of the hemodynamics was performed. VEMP was implanted as the total left heart bypass in adult goats and right heart circulation was maintained by natural hearts. In arterial blood pressure during maintain circulation by the high frequency blood flow, Mayer waves (0.01-0.15 Hz) were significantly decreased, though respiratory waves (0.25-0.40 Hz) were not significantly changed. These results suggest that circulatory regulatory system was influenced by the high frequency blood flow produced by the VEMP.
Yambe
T
T
Department of Medical Engineering and Cardiology, Tohoku University, Sendai, Japan.
Nitta
S
S
Katahira
Y
Y
Sonobe
T
T
Naganuma
S
S
Kakinuma
Y
Y
Akiho
H
H
Tanaka
M
M
Fukuju
T
T
Miura
M
M
D000818:Animals; D001775:Blood Circulation; D001794:Blood Pressure; D006041:Goats; D006354:Heart, Artificial; D012039:Regional Blood Flow