title: Pyogenic liver abscess: multivariate analysis of risk factors.
abstract: Seventy-three patients with pyogenic liver abscess during the year 1978-1988 were studied in the Kaohsiung Medical College Hospital. The overall mortality rate was 19.2% in this study. By using univariate analysis, it was revealed that clinical jaundice, pleural effusion, bilobar abscess, profound hypoalbuminemia (less than 2.5 g/dl), hyperbilirubinemia (less than 2 mg/dl), elevated level of serum AST (greater than 100 IU/L), alkaline phosphatase (greater than 150 IU/L), and marked leukocytosis (greater than 20,000 mm3) were associated with a higher mortality rate. Multivariate stepwise logistic regression analysis detected only 3 factors of marked leukocytosis (greater than 20,000 mm3), profound hypoalbuminemia (less than 2.5 g/dl), and presence of pleural effusion with independent significance in predicting mortality. Meanwhile, it was also revealed that the laboratory data could not predict a risk factor to mortality unless they became markedly abnormal.
authors.affiliation: Department of Surgery, Kaohsiung Medical College Hospital, Taiwan, Republic of China.
authors.forename: K T
authors.initials: KT
authors.lastname: Lee
authors.forename: P C
authors.initials: PC
authors.lastname: Sheen
authors.forename: J S
authors.initials: JS
authors.lastname: Chen
authors.forename: C G
authors.initials: CG
authors.lastname: Ker
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001419:Bacteria / Q000302:isolation & purification; D001424:Bacterial Infections / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology; D005260:Female; D006801:Humans; D008100:Liver Abscess / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013492:Suppuration