title: Hyperreninemic hypoaldosteronism due to hepatocellular carcinoma metastatic to the adrenal gland.
abstract: Metastases to the adrenal glands are common in patients with cancer, but among those affected, hyperreninemic hypoaldosteronism is noted very rarely. A case of hyperreninemic hypoaldosteronism secondary to metastatic hepatocellular carcinoma is reported. Laboratory data revealed selective aldosterone deficiency with hyperreninemia. Biopsy documented replacement of the adrenal glands with metastatic hepatocellular carcinoma. A review of the literature disclosed that the present case was an extremely rare one of its kind.
authors.affiliation: Department of Gastroenterology, Jichi Medical School, Tochigi, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Otabe
authors.forename: S
authors.initials: S
authors.lastname: Muto
authors.forename: Y
authors.initials: Y
authors.lastname: Asano
authors.forename: K
authors.initials: K
authors.lastname: Sato
authors.forename: M
authors.initials: M
authors.lastname: Ohtani
authors.forename: C
authors.initials: C
authors.lastname: Kawamoto
authors.forename: K
authors.initials: K
authors.lastname: Ido
authors.forename: K
authors.initials: K
authors.lastname: Kimura
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000556:secondary*; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000450:Aldosterone / Q000097:blood; D000804:Angiotensin II / Q000494:pharmacology; D006528:Carcinoma, Hepatocellular / Q000556:secondary*; D005665:Furosemide / Q000494:pharmacology; D006801:Humans; D006994:Hypoaldosteronism / Q000097:blood / Q000209:etiology*; D008113:Liver Neoplasms; D008297:Male; D008875:Middle Aged; D012083:Renin / Q000097:blood*; D000092502:Renin Inhibitors
chemical_list: D000324:Adrenocorticotropic Hormone; D000450:Aldosterone; D000804:Angiotensin II; D005665:Furosemide; D012083:Renin; D000092502:Renin Inhibitors