Antitumor imidazotetrazinones: prodrugs targeted to the major groove of DNA.
Stevens
M F
MF
Department of Pharmaceutical Sciences, Aston University, Birmingham, UK.
D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D004247:DNA / Q000737:chemistry / Q000187:drug effects*; D015195:Drug Design; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000494:pharmacology; D006801:Humans; D007093:Imidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D011355:Prodrugs / Q000138:chemical synthesis*; D013329:Structure-Activity Relationship
D000970:Antineoplastic Agents; D006571:Heterocyclic Compounds; D007093:Imidazoles; D011355:Prodrugs; D004247:DNA