Cocaethylene inhibits uptake of dopamine and can reach high plasma concentrations following combined cocaine and ethanol use.
Jatlow
P
P
Dept. of Laboratory Medicine, Yale University School of Medicine, New Haven, CT.
Hearn
W L
WL
Elsworth
J D
JD
Roth
R H
RH
Bradberry
C W
CW
Taylor
J R
JR
D000435:Alcoholic Intoxication / Q000503:physiopathology; D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D001923:Brain Chemistry / Q000187:drug effects; D003042:Cocaine / Q000031:analogs & derivatives* / Q000097:blood / Q000493:pharmacokinetics* / Q000494:pharmacology / Q000506:poisoning; D004298:Dopamine / Q000378:metabolism*; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D009043:Motor Activity / Q000187:drug effects; D051381:Rats
D000431:Ethanol; C066444:cocaethylene; D003042:Cocaine; D004298:Dopamine