Further possibilities of using aryloxycarbonic acid derivatives in clinical practice.
In medical practice aryloxycarbonic acid derivatives have been solely used in the treatment of hyperlipidemia. Recently we patented the use of some of these derivatives in the treatment of dermatological diseases. Further analyses showed that these substances stimulated various cells of mesodermal origin including lymphocytes, the principal cells of the immune system. Depending on the concentration some derivatives of aryloxycarbonic acid stimulated or suppressed the proliferative response of lymphocytes, pointing to the possible use of these drugs as immunomodulators in clinical practice as well.
Dorić
M
M
Department of Microbiology and Parasitology, Faculty of Medicine, University of Rijeka.
Gligora
M
M
D000924:Anticholesteremic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001629:Bezafibrate / Q000494:pharmacology* / Q000627:therapeutic use; D002994:Clofibrate / Q000494:pharmacology / Q000627:therapeutic use; D003240:Connective Tissue Diseases / Q000188:drug therapy*; D011345:Fenofibrate / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D008213:Lymphocyte Activation / Q000187:drug effects*; D010835:Phytohemagglutinins / Q000494:pharmacology
D000924:Anticholesteremic Agents; D010835:Phytohemagglutinins; D002994:Clofibrate; D011345:Fenofibrate; D001629:Bezafibrate