title: [The diagnosis of bladder carcinomas by NMR tomography: an improvement with Gd-DTPA?].
abstract: 85 patients suffering from urinary bladder carcinoma were examined by magnetic resonance imaging in a prospective study. Following precontrast diagnosis, 15 patients were given an intravesicular application of gadolinium-DTPA (Gd-DTPA). Another 35 patients received an intravenous bolus of GD-DTPA. A diagnostic advantage was achieved in only 2 of 15 tumours by using intravesicular contrast application. Compared to the precontrast diagnosis, a 14% improvement from 69% (precontrast) to 83% (contrast medium) was seen with Gd-DTPA applied intravenously in the diagnosis of the tumour stage. The diagnostic gain lies in the improved tumour recognition, the improved demarcation of papillary, non-muscle-infiltrating tumours and in the more definite diagnosis of infiltration into neighbouring organs and the pelvic wall. Demarcation of perivesicular fatty infiltration is rendered more difficult by Gd-DTPA.
authors.affiliation: Klinik für Radiologie, Abteilung für Röntgendiagnostik, Universitäts-Klinikum Steglitz, Freie Universität, Berlin.
authors.forename: A
authors.initials: A
authors.lastname: Sparenberg
authors.forename: B
authors.initials: B
authors.lastname: Hamm
authors.forename: P
authors.initials: P
authors.lastname: Hammerer
authors.forename: V
authors.initials: V
authors.lastname: Samberger
authors.forename: K J
authors.initials: KJ
authors.lastname: Wolf
mesh_terms: D000283:Administration, Intravesical; D002277:Carcinoma / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D003287:Contrast Media / Q000008:administration & dosage; D004341:Drug Evaluation; D005260:Female; D005682:Gadolinium / Q000008:administration & dosage; D019786:Gadolinium DTPA; D006801:Humans; D007275:Injections, Intravenous; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data; D008297:Male; D009367:Neoplasm Staging; D009942:Organometallic Compounds / Q000008:administration & dosage; D004369:Pentetic Acid / Q000008:administration & dosage; D011446:Prospective Studies; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA
vernacular_title: Diagnostik von Harnblasenkarzinomen in der Kernspintomographie: Verbesserung mit Gd-DTPA?