title: [A long-term follow-up of a patient with DIDMOAD (Wolfram) syndrome].
abstract: A 19-year-old Japanese woman developed diabetes mellitus, diabetes insipidus and optic atrophy. Other abnormal ocular findings included color blindness, elevated dark adaptation threshold and constriction of visual fields. Diabetic retinopathy, which is considered to be rare in this syndrome, also was found in the fundi of this patient. During the nine-year follow-up period, diabetic retinopathy deteriorated despite treatment by photocoagulation and vitrectomy, suggesting the importance of ophthalmological examinations in patients with DIDMOAD syndrome.
authors.affiliation: Department of Ophthalmology, Tohoku University School of Medicine, Sendai, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Shiono
authors.forename: M
authors.initials: M
authors.lastname: Noro
authors.forename: S
authors.initials: S
authors.lastname: Abe
mesh_terms: D000328:Adult; D003930:Diabetic Retinopathy / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008028:Light Coagulation; D014821:Vitrectomy; D014929:Wolfram Syndrome / Q000473:pathology*