title: HIV protease: a novel chemotherapeutic target for AIDS.
authors.affiliation: Department of Medicinal Chemistry, Merck Sharp and Dohme Research Laboratories, West Point, Pennsylvania 19486.
authors.forename: J R
authors.initials: JR
authors.lastname: Huff
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D000595:Amino Acid Sequence; D016282:Aspartic Acid Endopeptidases / Q000737:chemistry; D016333:HIV Protease / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D017320:HIV Protease Inhibitors; D015497:HIV-1 / Q000201:enzymology; D006801:Humans; D008969:Molecular Sequence Data; D015394:Molecular Structure; D016297:Mutagenesis, Site-Directed; D013379:Substrate Specificity; D014779:Virus Replication
chemical_list: D017320:HIV Protease Inhibitors; D016282:Aspartic Acid Endopeptidases; D016333:HIV Protease