Dependence studies of new compounds in the rhesus monkey and mouse (1990).
Norcocaine dose-dependently attenuates abrupt morphine withdrawal in rhesus monkeys. These results suggest a possible role for this metabolite in the interaction of cocaine with the opioid system.
Aceto
M D
MD
Department of Pharmacology and Toxicology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298-0613.
Bowman
E R
ER
Harris
L S
LS
May
E L
EL
D000818:Animals; D008253:Macaca mulatta; D051379:Mice; D011930:Reaction Time / Q000187:drug effects; D013375:Substance Withdrawal Syndrome / Q000523:psychology; D019966:Substance-Related Disorders / Q000523:psychology*