A correlation between muscular strength and hydroxyproline concentration in human patellar tendon.
The connective tissue of the knee is frequently injured by athletes, especially those involved in contact sports. It would be important in the prevention of injury as well as the strategy of physical fitness training to know whether the connective tissue is modified in response to athletic stress or training. The potential modification investigated was variability in the concentration of hydroxyproline, a post-translationally modified imino acid found principally in collagen protein. A correlation was sought between this variability and the leg strength parameters torque (expressed as ft-lbs), torque/body weight and work (expressed as ft-lbs). In a preliminary study of five subjects, no correlation was found between hydroxyproline concentration of the patellar tendon and any of the leg strength parameters. These results suggest that this modification of the collagen in connective tissue does not occur in response to athletic stress or training, but rather, for the small number of subjects investigated, appeared to be relatively constant across a range of leg strengths.
Lemley
P V
PV
Department of Chemistry, United States Military Academy, West Point, N.Y.
Welch
M J
MJ
D003094:Collagen / Q000378:metabolism*; D005260:Female; D006801:Humans; D006909:Hydroxyproline / Q000378:metabolism*; D007719:Knee Joint / Q000378:metabolism* / Q000502:physiology; D008297:Male; D009119:Muscle Contraction; D013710:Tendons / Q000378:metabolism*
D003094:Collagen; D006909:Hydroxyproline