Chemotherapy of metastatic Merkel cell cancer.
Out of 16 cases of Merkel cell cancer identified in the records of the Mt. Sinai Medical Center or affiliates, 11 patients developed systemic metastases. Literature review confirms the substantial possibility of dissemination. Both in our series and in the literature, cytotoxic chemotherapy produced a high rate of usually short-lived response, although one of our patients with disseminated metastases achieved complete remission for two years.
Crown
J
J
Department of Neoplastic Diseases, Mount Sinai Medical Center, New York, New York 10029.
Lipzstein
R
R
Cohen
S
S
Goldsmith
M
M
Wisch
N
N
Paciucci
P A
PA
Silverman
L
L
Weiner
M
M
Jaffrey
I
I
Norton
L
L
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D015266:Carcinoma, Merkel Cell / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000188:drug therapy*