Structure and possible function of Plasmodium falciparum proteins exported to the erythrocyte membrane.
On infecting the red blood cell, the malaria parasite Plasmodium falciparum induces alterations in the erythrocyte membrane. The parasite appears to synthesize proteins that are exported across the parasitophorous vacuole membrane and through a system of membraneous structures within the cytoplasm of the host cell to the surface membrane of the erythrocyte. There, these proteins are either released or remain associated with the membrane. In this review we describe the structure and discuss the possible functions of some of the exported proteins.
Knapp
B
B
Department of Microbiology, Behringwerke AG, Marburg, Federal Republic of Germany.
Hundt
E
E
Lingelbach
K R
KR
D000818:Animals; D000953:Antigens, Protozoan / Q000737:chemistry* / Q000276:immunology / Q000502:physiology; D000954:Antigens, Surface / Q000737:chemistry / Q000276:immunology / Q000502:physiology; D004910:Erythrocyte Membrane / Q000737:chemistry / Q000276:immunology / Q000469:parasitology*; D006801:Humans; D010963:Plasmodium falciparum / Q000276:immunology / Q000502:physiology*; D015800:Protozoan Proteins / Q000737:chemistry* / Q000276:immunology
D000953:Antigens, Protozoan; D000954:Antigens, Surface; D015800:Protozoan Proteins