title: Collateral circulation as a marker of the presence of viable myocardium in patients with recent myocardial infarction.
abstract: The relationship between the presence of viable myocardium and the extent of coronary collateral circulation to the infarct area was evaluated in 20 patients with a recent anterior myocardial infarction who had complete obstruction of the left anterior descending coronary artery. The viability of myocardial tissue was assessed by exercise thallium-201 myocardial scintigraphy, and the collateral circulation was angiographically evaluated by means of a collateral index ranging from 0 to 3. Patients were divided into two groups according to the presence (group 1, n = 10) or absence (group 2, n = 10) of viable myocardium in the perfusion territory of the infarct-related artery. The collateral index in group 1 was 2.5 +/- 0.5 (SD), which was significantly higher than the 0.7 +/- 0.8 in group 2. These findings indicate that the presence of ischemic but viable myocardium is intimately related to the development of collateral circulation in patients with myocardial infarction, and the existence of well-developed collateral channels predicts the presence of viable myocardium in the infarct area.
authors.affiliation: Second Department of Internal Medicine, Toyama Medical and Pharmaceutical University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Fujita
authors.forename: A
authors.initials: A
authors.lastname: Ohno
authors.forename: O
authors.initials: O
authors.lastname: Wada
authors.forename: K
authors.initials: K
authors.lastname: Miwa
authors.forename: T
authors.initials: T
authors.lastname: Nozawa
authors.forename: K
authors.initials: K
authors.lastname: Yamanishi
authors.forename: S
authors.initials: S
authors.lastname: Sasayama
mesh_terms: D003097:Collateral Circulation / Q000502:physiology*; D017023:Coronary Angiography; D003326:Coronary Circulation / Q000502:physiology*; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology*; D011877:Radionuclide Imaging; D013794:Thallium Radioisotopes; D016277:Ventricular Function, Left / Q000502:physiology
chemical_list: D013794:Thallium Radioisotopes