Turkey and chicken prolactins stimulate the proliferation of rat Nb2 lymphoma cells.
The purpose of this investigation was to assess the actions of two avian prolactins (PRL) on rat Nb2 lymphoma cell proliferation. Various turkey and chicken PRL preparations stimulated the proliferation of rat Nb2 cells. The ability of avian PRL preparations to influence the behavior of rat Nb2 lymphoma cells provides a useful method for monitoring the PRL-like actions of native and recombinant avian PRL and suggests a potential role of PRL in modulating the avian immune system.
Soares
M J
MJ
Department of Physiology, University of Kansas Medical Center, Kansas City 66103.
Proudman
J A
JA
D000818:Animals; D002645:Chickens; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology*; D008223:Lymphoma; D011388:Prolactin / Q000494:pharmacology*; D011863:Radioimmunoassay; D051381:Rats; D014407:Tumor Cells, Cultured; D014422:Turkeys
D011388:Prolactin