Development of an inductive, non-invasive RF applicator for studying hyperthermia in a rat brain tumour model.
A non-invasive inductive RF applicator has been designed specially for local heating of 6 mm diameter tumours growing in the brains of F344 rats (144-148 MHz). It is shown that an inductive applicator is the choice for this particular case. The power deposition pattern is analysed by modelling the applicator with a three-dimensional array of magnetic dipoles. The total hyperthermia system is briefly described and results of phantom and in vivo experimental measurements are presented. These confirm the theoretical analysis.
Heinzl
L
L
Ontario Cancer Institute, Toronto, Canada.
Hunt
J W
JW
Bernstein
M
M
D000818:Animals; D055592:Biophysical Phenomena; D001703:Biophysics; D001932:Brain Neoplasms / Q000628:therapy*; D003198:Computer Simulation; D005069:Evaluation Studies as Topic; D006979:Hyperthermia, Induced / Q000295:instrumentation*; D008961:Models, Structural; D008962:Models, Theoretical; D011846:Radio Waves; D051381:Rats; D011916:Rats, Inbred F344