title: [Eighty cases of alveolar hydatid disease treated with albendazole].
abstract: Alveolar hydatid disease occurs frequently in Xiji County of Ningxia. 80 cases of the disease were treated orally with albendazole from 1985 to 1988 and the short-term results proved satisfactory. The treatment consisted of two groups. Group I included 72 cases which were orally given 8-10 mg/kg.d of albendazole 2 to 3 times a day after each meal for 30 days and then stop taking the medicine for 10 days as one treatment course. The treatment continued 3-12 months comprising about 24 courses were given with the highest dosage of 412g. Group II included 8 cases who were given 15.6-20 mg/kg.d of the medicine for 14 days (one course) and every two weeks with a 10 days interval. The treatment of group II continued 3-6 months which totalled 19-24 courses with the highest dosage of 270g. All the treated patients tolerate well except that a few of them felt giddy and had diarrhoea which disappeared after the withdrawal of medicine. Through 3-5 years, follow-up observation, it was found that the gener alsymptoms of the treated patients improved and their body weight increased by 2-9.5 kg, some of them could take part in light physical labour. The jaundice index in 80% of them returned to normal. SGPT in 86.4% decreased to within normal range. The enlarged livers in half of the patients decreased by 1-6 cm. 23.7% of the patients were reexamined by B ultrasound scanning which revealed that their enlarged liver reduced in size while the liquifaction area and the shadows of calcification in the livers in 42.5% patients increased obviously.
authors.affiliation: People's Hospital of Xiji County, Ningxia.
authors.forename: M
authors.initials: M
authors.lastname: Li
authors.forename: W X
authors.initials: WX
authors.lastname: Li
authors.forename: X Z
authors.initials: XZ
authors.lastname: Liu
authors.forename: W J
authors.initials: WJ
authors.lastname: Li
authors.forename: G C
authors.initials: GC
authors.lastname: Huang
authors.forename: G C
authors.initials: GC
authors.lastname: Zhang
authors.forename: Q H
authors.initials: QH
authors.lastname: Wang
authors.forename: X L
authors.initials: XL
authors.lastname: Wang
authors.forename: S Y
authors.initials: SY
authors.lastname: Li
authors.forename: M Z
authors.initials: MZ
authors.lastname: Li
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015766:Albendazole / Q000008:administration & dosage*; D004444:Echinococcosis, Hepatic / Q000145:classification / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D015766:Albendazole