title: Serum selenium and coronary heart disease risk factors in southern Italian men.
abstract: The association between serum selenium concentration and a number of coronary heart disease risk factors is studied in 364 males from southern Italy participating in the Olivetti Heart Study. Selenium correlates positively and significantly with serum cholesterol (r = 0.120; P = 0.022), and this positive association persists after adjustment for age and body mass index. Selenium levels in heavy smokers are lower than both light smokers and current non-smokers, but these differences do not reach statistical significance. Selenium is not significantly associated with any of the other CHD risk factors (e.g., triglycerides, HDL cholesterol, blood pressure, age, and body mass index). It is hypothesized that the association between selenium and serum cholesterol reported in this and previous studies could be due to dietary interrelationships between selenium intake and foods that affect serum cholesterol concentrations.
authors.affiliation: Department of Social and Preventive Medicine, State University of New York, Buffalo 14214.
authors.forename: F
authors.initials: F
authors.lastname: Jossa
authors.forename: M
authors.initials: M
authors.lastname: Trevisan
authors.forename: V
authors.initials: V
authors.lastname: Krogh
authors.forename: E
authors.initials: E
authors.lastname: Farinaro
authors.forename: D
authors.initials: D
authors.lastname: Giumetti
authors.forename: G
authors.initials: G
authors.lastname: Fusco
authors.forename: R
authors.initials: R
authors.lastname: Galasso
authors.forename: S
authors.initials: S
authors.lastname: Panico
authors.forename: S
authors.initials: S
authors.lastname: Frascatore
authors.forename: C
authors.initials: C
authors.lastname: Mellone
mesh_terms: D000328:Adult; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D003327:Coronary Disease / Q000097:blood*; D006801:Humans; D007558:Italy; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012643:Selenium / Q000097:blood*; D012907:Smoking
chemical_list: D002784:Cholesterol; D012643:Selenium