title: A new balanced operation for complex gastroesophageal reflux disease.
abstract: Twenty-seven patients with advanced gastroesophageal reflux disease have been treated with combined transthoracic parietal cell vagotomy and Collis-Nissen fundoplication. Gastric acid analyses (n = 20) obtained preoperatively and 6 months postoperatively demonstrated a significant late reduction in gastric acid output. Twenty-six patients (96%) have experienced relief of gastroesophageal reflux disease at a mean of 13.3 months (range, 6 to 25 months) without postvagotomy symptoms. Transthoracic parietal cell vagotomy may be considered as an adjunct to mechanical surgical control of advanced gastroesophageal reflux disease.
authors.affiliation: Division of Cardiothoracic Surgery, University of Missouri School of Medicine, Columbia.
authors.forename: R J
authors.initials: RJ
authors.lastname: Landreneau
authors.forename: J B
authors.initials: JB
authors.lastname: Marshall
authors.forename: J A
authors.initials: JA
authors.lastname: Johnson
authors.forename: T M
authors.initials: TM
authors.lastname: Boley
authors.forename: S R
authors.initials: SR
authors.lastname: Hazelrigg
authors.forename: J J
authors.initials: JJ
authors.lastname: Curtis
authors.forename: R N
authors.initials: RN
authors.lastname: McClelland
mesh_terms: D000328:Adult; D000368:Aged; D004947:Esophagus / Q000601:surgery*; D005260:Female; D005748:Gastric Fundus / Q000601:surgery*; D005764:Gastroesophageal Reflux / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013908:Thoracotomy / Q000379:methods; D014629:Vagotomy, Proximal Gastric