title: [The experimental and clinical effect of ciprofloxacin on the microflora of the gastrointestinal tract].
abstract: The study of the influence of cyprofloxacin on the microflora of the gastrointestinal tract has been made under experimental and clinical conditions. As revealed in this study, cyprofloxacin produces a corrective effect on the intestinal microflora; the action of this preparation, in contrast to that of other antimicrobial preparations, is retained for a long time. In patients having duodenal ulcer with bacteriosis caused by Campylobacter pylori and with intestinal dysbacteriosis the combination of cyprofloxacin and cimetidine yields a higher therapeutic effect than the use of cimetidine alone.
authors.forename: V M
authors.initials: VM
authors.lastname: Korshunov
authors.forename: A A
authors.initials: AA
authors.lastname: Il'chenko
authors.forename: L G
authors.initials: LG
authors.lastname: Dugasheva
authors.forename: L A
authors.initials: LA
authors.lastname: Romanchuk
authors.forename: W
authors.initials: W
authors.lastname: Busch
authors.forename: E D
authors.initials: ED
authors.lastname: Radakova
authors.forename: V G
authors.initials: VG
authors.lastname: Zhukhovitskiĭ
authors.forename: V S
authors.initials: VS
authors.lastname: Gorodinskaia
mesh_terms: D000328:Adult; D000583:Amikacin / Q000494:pharmacology; D000818:Animals; D002927:Cimetidine / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000494:pharmacology* / Q000627:therapeutic use; D004064:Digestive System / Q000187:drug effects* / Q000382:microbiology*; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D004381:Duodenal Ulcer / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D005856:Germ-Free Life / Q000187:drug effects; D016481:Helicobacter Infections / Q000188:drug therapy / Q000382:microbiology; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D008875:Middle Aged; D015366:Pefloxacin / Q000494:pharmacology; D013997:Time Factors
chemical_list: D015366:Pefloxacin; D002939:Ciprofloxacin; D002927:Cimetidine; D000583:Amikacin
vernacular_title: Vliianie tsiprofloksatsina na mikrofloru zheludochno-kishechnogo trakta v éksperimente i klinike.