title: Impact of preoperative CA 15-3 levels in operable breast cancer. Comparison with tissue polypeptide antigen (TPA) and carcinoembryonic antigen (CEA).
abstract: CA 15-3, TPA and CEA were assayed before surgery in 60 patients with breast cancer. A significant association was found between preoperative CA 15-3 levels and some of the most important prognostic factors in breast cancer, such as lymph node status and tumor size. No similar association was discovered for CEA and TPA. Preoperative CA 15-3 levels were also significantly associated with early recurrences of the disease, thus adding useful information to prognosis especially in N+ patients.
authors.affiliation: Division of Medical Oncology, University of Cagliari, Italy.
authors.forename: R V
authors.initials: RV
authors.lastname: Iaffaioli
authors.forename: F
authors.initials: F
authors.lastname: Caponigro
authors.forename: G
authors.initials: G
authors.lastname: Esposito
authors.forename: C
authors.initials: C
authors.lastname: Pagliarulo
authors.forename: S
authors.initials: S
authors.lastname: Deplacido
authors.forename: B
authors.initials: B
authors.lastname: Ungaro
authors.forename: L
authors.initials: L
authors.lastname: Bazzicalupo
authors.forename: G
authors.initials: G
authors.lastname: Frasci
authors.forename: A R
authors.initials: AR
authors.lastname: Bianco
mesh_terms: D015295:Antigens, Tumor-Associated, Carbohydrate / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood*; D001943:Breast Neoplasms / Q000097:blood* / Q000473:pathology / Q000601:surgery; D002272:Carcinoembryonic Antigen / Q000097:blood*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D008593:Menopause; D010455:Peptides / Q000097:blood*; D011379:Prognosis; D019396:Tissue Polypeptide Antigen
chemical_list: D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D010455:Peptides; D019396:Tissue Polypeptide Antigen