Deficiency of IgG subclasses and IgA, and elevation of IgE in children with a past history of bacterial meningitis.
Of 44 children who recovered from an attack of bacterial meningitis, 3 (7%) were found to have IgG subclass deficiency, 5 (11%) had IgA deficiency and 22 (50%) had raised IgE levels. These results suggest that immunoglobulin abnormalities may be an important predisposing factor in some cases of bacterial meningitis.
Loh
R K
RK
Department of Child Health, University of Queensland, Mater Children's Hospital, South Brisbane, Australia.
Thong
Y H
YH
Ferrante
A
A
D001424:Bacterial Infections / Q000150:complications / Q000276:immunology* / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D004406:Dysgammaglobulinemia / Q000209:etiology / Q000276:immunology* / Q000378:metabolism; D005260:Female; D006801:Humans; D017098:IgA Deficiency; D017099:IgG Deficiency; D007073:Immunoglobulin E / Q000378:metabolism*; D007223:Infant; D008297:Male; D008581:Meningitis / Q000150:complications / Q000276:immunology* / Q000378:metabolism
D007073:Immunoglobulin E