title: Inhibitory effects of human salivary histatins and lysozyme on coaggregation between Porphyromonas gingivalis and Streptococcus mitis.
abstract: The effects of histatins on coaggregation between Porphyromonas gingivalis 381 and Streptococcus mitis ATCC 9811 were investigated by using a turbidimetric assay. The coaggregation activity was significantly inhibited by histatins 5 and 8 and strongly by lysozyme. Tritium-labeled histatin 8 bound to P. gingivalis cells but not to S. mitis cells.
authors.affiliation: Department of Preventive Dentistry, Faculty of Dentistry, Osaka University, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Murakami
authors.forename: H
authors.initials: H
authors.lastname: Nagata
authors.forename: A
authors.initials: A
authors.lastname: Amano
authors.forename: M
authors.initials: M
authors.lastname: Takagaki
authors.forename: S
authors.initials: S
authors.lastname: Shizukuishi
authors.forename: A
authors.initials: A
authors.lastname: Tsunemitsu
authors.forename: S
authors.initials: S
authors.lastname: Aimoto
mesh_terms: D000595:Amino Acid Sequence; D001422:Bacterial Adhesion; D001439:Bacteroides / Q000378:metabolism / Q000502:physiology*; D006801:Humans; D008969:Molecular Sequence Data; D009113:Muramidase / Q000494:pharmacology*; D011506:Proteins / Q000494:pharmacology*; D012471:Salivary Proteins and Peptides / Q000494:pharmacology*; D013291:Streptococcus / Q000378:metabolism / Q000502:physiology*; D000099053:Histidine-Rich Glycoprotein
chemical_list: D011506:Proteins; D012471:Salivary Proteins and Peptides; D000099053:Histidine-Rich Glycoprotein; D009113:Muramidase