title: Hydrolysed microspheres from cross-linked polymethyl methacrylate (Hydrogel). A new embolic material for interventional neuroradiology.
abstract: Highly hydrophilic, perfectly smooth and spherical microspheres have been synthetized. These non-biodegradable microspheres absorb water in varying degrees and can be injected easily through microcatheters due to their slippery and compressible characteristics. The material was successfully used for embolization of 4 vascular intracranial tumours and 2 spinal vascular lesions in the cervical region, by superselective delivery. Histopathology confirmed absolute inertness of the microspheres.
authors.affiliation: Department of radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.
authors.forename: V R
authors.initials: VR
authors.lastname: Rao
authors.forename: K
authors.initials: K
authors.lastname: Ravimandalam
authors.forename: A
authors.initials: A
authors.lastname: Jayakrishnan
authors.forename: B C
authors.initials: BC
authors.lastname: Thanoo
authors.forename: V V
authors.initials: VV
authors.lastname: Radhakrishnan
authors.forename: A K
authors.initials: AK
authors.lastname: Gupta
authors.forename: S
authors.initials: S
authors.lastname: Kumar
authors.forename: S
authors.initials: S
authors.lastname: Joseph
authors.forename: M
authors.initials: M
authors.lastname: Unni
authors.forename: A S
authors.initials: AS
authors.lastname: Rao
mesh_terms: D000328:Adult; D015901:Angiography, Digital Subtraction; D001165:Arteriovenous Malformations / Q000628:therapy; D001932:Brain Neoplasms / Q000628:therapy; D002404:Catheterization; D002648:Child; D004621:Embolization, Therapeutic / Q000295:instrumentation* / Q000379:methods; D005260:Female; D006801:Humans; D006868:Hydrolysis; D008297:Male; D008579:Meningioma / Q000098:blood supply / Q000628:therapy; D008768:Methylmethacrylates / Q000138:chemical synthesis / Q000737:chemistry; D008863:Microspheres; D008875:Middle Aged; D015642:Radiology, Interventional; D013131:Spine / Q000098:blood supply; D014711:Vertebral Artery / Q000002:abnormalities
chemical_list: D008768:Methylmethacrylates