title: [Familial form of gelatin drop corneal dystrophy].
abstract: We report 4 cases of gelatin drop dystrophy corneal amyloidosis in two brothers and two sisters of the same family. The age of onset is between 1 and 10 years. The corneal signs are described at different stages of development. Lesions are initially asymmetrical. The typical is a subepithelial nodule starting in the center and then expanding to involve the whole cornea. There is no relationship between extension and outcome of the disease. Diagnostic is confirmed by histological examination. There was no consanguinity between parents and no other cases were found in the family. An immunological study with HLA typing was performed. All patients were treated with lamellar or transfixing keratoplasty with a follow-up of 2 to 5 years.
authors.affiliation: Institut d'Ophtalmologie, Tunis, Tunisie.
authors.forename: L
authors.initials: L
authors.lastname: el Matri
authors.forename: A
authors.initials: A
authors.lastname: Bachtobji
authors.forename: M
authors.initials: M
authors.lastname: Ghorbal
authors.forename: J
authors.initials: J
authors.lastname: Maamri
authors.forename: M
authors.initials: M
authors.lastname: Kamoun
authors.forename: A
authors.initials: A
authors.lastname: Ouertani
authors.forename: R
authors.initials: R
authors.lastname: Bardi
authors.forename: M F
authors.initials: MF
authors.lastname: Triki
mesh_terms: D000293:Adolescent; D000328:Adult; D003317:Corneal Dystrophies, Hereditary / Q000235:genetics* / Q000473:pathology; D005260:Female; D005780:Gelatin; D006801:Humans; D008297:Male
chemical_list: D005780:Gelatin
vernacular_title: Forme familiale de dystrophie gélatineuse en gouttes de la cornée.