title: Enhancement of fracture healing by specific pulsed capacitively-coupled electric field stimulation.
abstract: The histologic procedure technique was used to evaluate the bone fracture healing rate of manually fractured fibulae after they were submitted to several different types of capacitively-coupled electric field stimulation, classified depending on the parameters of peak-to-peak voltage, frequency and duration. Using a completely randomized design, 30 New Zealand male rabbits were divided into six different groups: a control group, a 60 kHz and 220 mVp-p sine wave group as proposed by Brighton in 1985, and four special parameters of pulse wave groups. After comparing these different types of electrical stimulation, the group with the parameters of a pulse train repetition frequency of 15 Hz, a pulse frequency of 10 kHz and 5 V peak-to-peak intensity experienced the same enhancement of bone fracture healing as the group with the parameters suggested by Brighton in 1985.
authors.affiliation: Department of Biomedical Engineering, Chung Yuan Christian University, Taiwan, ROC.
authors.forename: W H
authors.initials: WH
authors.lastname: Chang
authors.forename: I M
authors.initials: IM
authors.lastname: Hwang
authors.forename: H C
authors.initials: HC
authors.lastname: Liu
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000502:physiology; D004553:Electric Conductivity; D004558:Electric Stimulation; D050723:Fractures, Bone / Q000503:physiopathology*; D010012:Osteogenesis / Q000502:physiology; D011817:Rabbits; D011897:Random Allocation; D014945:Wound Healing / Q000502:physiology