A probe for measuring current density during magnetic stimulation.
Time-varying magnetic fields induce currents in conductive media, and when the induced current is large enough in excitable tissue, stimulation occurs. This phenomenon has been applied to the human brain and peripheral nerves for diagnostic evaluation of the neural system. One important aspect that is presently unknown is the current level necessary in tissue for stimulation induced by magnetic fields. This study presents a method of measuring the induced current density from pulsed magnetic fields in vitro and in vivo. The current-density probe was inserted into three concentrations of saline and into the brains of ten anesthetized cats. Two stimulation systems with coils 9 cm and 5 cm in diameter were used. The two systems provided sinusoidal and pulsatile coil currents. Measurements made in saline were compared with those calculated theoretically for a semi-infinite medium. The measured values were within 5% of the calculated values. Measurements made in the cat brain showed a 67% decrease compared with the theoretic model. This variance is attributed to the finite bounds of the skull. The results indicate that direct measurement of current density is possible. Subsequent measurements will aid in the design of improved magnetic stimulation systems.
Tay
G
G
Department of Neurosurgery, Medical College of Wisconsin, Milwaukee.
Chilbert
M A
MA
Battocletti
J
J
Sances
A
A
Swiontek
T
T
D000818:Animals; D001931:Brain Mapping; D002138:Calibration; D002415:Cats; D004553:Electric Conductivity; D004558:Electric Stimulation; D004574:Electromagnetic Fields