title: A comparative investigation on autologous mandibular and iliac crest bone grafts. An experimental study in sheep.
abstract: Nine Friesian sheep (age 1.5-2 years) were used to evaluate the quality of bone repair in artificial cleft-like maxillary defects repaired with autologous bone grafts of embryologically different origin. After bilateral extraction of the upper first deciduous molar the tooth socket was enlarged resulting in an open connection between the oral and nasal cavities. In the same session a graft, obtained from the iliac crest, was implanted in one of the two bilateral maxillary defects and on the opposite side a graft, obtained from the mandible, was inserted. During the experiment, serial radiographs were taken. After six months the sheep were sacrificed and the bone of the grafted areas was submitted to histological and histomorphometric investigation. Comparing both areas, it appeared that the quality of bone remodelling and alveolar reconstruction was independent of the origin of the grafts.
authors.affiliation: Department of Oral and Maxillofacial Surgery, University Hospital Utrecht, The Netherlands.
authors.forename: R
authors.initials: R
authors.lastname: Koole
authors.forename: W J
authors.initials: WJ
authors.lastname: Visser
authors.forename: W R
authors.initials: WR
authors.lastname: Klein
authors.forename: A M
authors.initials: AM
authors.lastname: Suiker
mesh_terms: D000539:Alveolar Process / Q000000981:diagnostic imaging / Q000473:pathology; D000543:Alveoloplasty; D000818:Animals; D015519:Bone Density; D016025:Bone Transplantation; D007085:Ilium / Q000473:pathology / Q000637:transplantation*; D008334:Mandible / Q000473:pathology / Q000637:transplantation*; D008437:Maxilla / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D010006:Osteoblasts / Q000473:pathology; D010010:Osteoclasts / Q000473:pathology; D010012:Osteogenesis; D011859:Radiography; D012756:Sheep; D014182:Transplantation, Autologous; D014945:Wound Healing