title: Pre-clinical toxicity of IDPH-791: a new centrally acting muscle relaxant in rats.
abstract: IDPH-791, a novel centrally acting muscle relaxant, in doses up to 500 mg/kg (po) for 14 days did not result in any appreciable adverse effect on body weight gain, food or water consumption including biochemical and haematologica parameters in rats. Variations observed in the biochemistry and haematology were either comparable to controls or were within normal limits.
authors.affiliation: Biology Division, IDPL Research Centre, Hyderabad, India.
authors.forename: R K
authors.initials: RK
authors.lastname: Varma
authors.forename: M
authors.initials: M
authors.lastname: Rajasekaran
authors.forename: A Y
authors.initials: AY
authors.lastname: Junnarkar
authors.forename: P P
authors.initials: PP
authors.lastname: Singh
authors.forename: A
authors.initials: A
authors.lastname: Krishnamurthy
authors.forename: G S
authors.initials: GS
authors.lastname: Thapar
authors.forename: M R
authors.initials: MR
authors.lastname: Marathe
mesh_terms: D000818:Animals; D005260:Female; D008297:Male; D009125:Muscle Relaxants, Central / Q000633:toxicity*; D051381:Rats; D011919:Rats, Inbred Strains; D013843:Thiazines / Q000633:toxicity*; D014230:Triazoles / Q000633:toxicity*
chemical_list: D009125:Muscle Relaxants, Central; D013843:Thiazines; D014230:Triazoles; C070154:IDPH-791