Mixed transcortical aphasia: clinical features and neuroanatomical correlates. A possible role of the right hemisphere.
This paper reports the clinical features of 2 patients affected by mixed transcortical aphasia. Both of them had extensive damage of the left hemisphere. Cerebral blood flow measurement showed a marked decrease in left-hemisphere flow. In particular, speech areas were found to be morphologically and functionally damaged. The present findings, together with a critical review of the literature, served as a starting point for a discussion of linguistic features, diagnostic criteria and classical neuroanatomical interpretation of mixed transcortical aphasia. The possible contribution of the right hemisphere in determining this aphasic syndrome is suggested.
Grossi
D
D
II Clinica Neurologica, II Facoltà di Medicina, Napoli, Italia.
Trojano
L
L
Chiacchio
L
L
Soricelli
A
A
Mansi
L
L
Postiglione
A
A
Salvatore
M
M
D000368:Aged; D001037:Aphasia / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D002540:Cerebral Cortex / Q000473:pathology; D002560:Cerebrovascular Circulation; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D015899:Tomography, Emission-Computed, Single-Photon