title: Gentamycin beads in the treatment of localised vascular graft infection--long term results in 17 cases.
abstract: Seventeen patients were treated by the implantation of gentamycin beads for localised Szilagyi type III prosthetic graft infection. Three patients had a pan prosthetic infection and half of the remaining patients were cured, but three of these died from other causes within 3 months. The mean observation time of the four survivors was 20 months (7-39 months). One of the seven patients, in whom the gentamycin beads failed, died of infection, giving a total mortality rate of 6% (1.5-29%). The remaining patients were cured after resection of the infected segment of the prosthesis at a mean follow-up of 22 months (8-37 months).
authors.affiliation: Department of Vascular Surgery RK, Rigshospitalet, University Hospital of Copenhagen, Denmark.
authors.forename: O M
authors.initials: OM
authors.lastname: Nielsen
authors.forename: H H
authors.initials: HH
authors.lastname: Noer
authors.forename: L G
authors.initials: LG
authors.lastname: Jørgensen
authors.forename: J E
authors.initials: JE
authors.lastname: Lorentzen
mesh_terms: D000368:Aged; D001162:Arteriosclerosis Obliterans / Q000601:surgery*; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D004343:Drug Implants; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage*; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D011512:Proteus Infections / Q000188:drug therapy* / Q000209:etiology; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000209:etiology; D013530:Surgical Wound Infection / Q000188:drug therapy* / Q000209:etiology; D013997:Time Factors
chemical_list: D004343:Drug Implants; D005839:Gentamicins