[Immunohistochemical study of meconial antigens in neoplasms and mucosa of the colon and rectum].
The expression of 4 meconial antigens--beta-1-MA, beta-2-MA, MMA, gamma-MA in neoplastic and preneoplastic colonic mucosa was studied. Meconial antigens were revealed in small amount in adult normal colonic epithelium. The mucosa adjacent to tumours was rich in these antigens. Cellular localization of meconial antigens in these parts of colonic mucosa was similar to that of embryonal alimentary tract. beta-1-MA was found in 96%, beta-2-MA--73.6%, MMA--82.8%, gamma-MA--31.8% of colonic carcinomas.
Frank
G A
GA
Pugachev
K K
KK
Shimbireva
I B
IB
Egorova
S G
SG
D000941:Antigens / Q000032:analysis*; D000951:Antigens, Neoplasm / Q000032:analysis*; D003106:Colon / Q000276:immunology; D003110:Colonic Neoplasms / Q000276:immunology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007413:Intestinal Mucosa / Q000276:immunology*; D008470:Meconium / Q000276:immunology*; D011230:Precancerous Conditions / Q000276:immunology
D000941:Antigens; D000951:Antigens, Neoplasm; C063420:beta1-meconial antigen
Immunogistokhimicheskoe izuchenie mekonial'nykh antigenov v novoobrazovaniiakh i slizistoĭ obolochke tolstoĭ i priamoĭ kishok.