Noninvasive measurement of transmural gradients in myocardial strain with MR imaging.
A method is presented for performing high-resolution strain measurements by using magnetic resonance (MR) tagging. Multispectral radiofrequency pulses are used to produce tagging grids from which strain estimates are obtained with a resolution of 2 mm. A tag detection algorithm is presented that measures the center of a tag line with a precision that ranges from 0.1 to 0.2 mm over the systolic interval. With this method, a transmural gradient in the strain of a normal dog heart was detected.
McVeigh
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ER
Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
Zerhouni
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EA
D000818:Animals; D004285:Dogs; D006321:Heart / Q000033:anatomy & histology* / Q000502:physiology; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008961:Models, Structural