title: Magnetic resonance imaging of hyperbaric oxygen treated rats with spinal cord injury: preliminary studies.
abstract: Magnetic resonance imaging (MRI) has been performed to assess the efficacy of hyperbaric oxygen (HBO) treatment on experimental spinal cord injury in a rat animal model. A moderately severe injury, similar to Type III injury seen in humans (Kulkarni et al. Radiology 164:837;1987) has been chosen for these studies. An improvement in the neurologic recovery (based on Tarlov scale) has been observed following HBO treatment over a period of 72 hr. Based on MRI, HBO treatment appears to arrest the spread of hemorrhage and resolve edema.
authors.affiliation: Department of Radiology, University of Texas Medical School, Houston 77030.
authors.forename: P A
authors.initials: PA
authors.lastname: Narayana
authors.forename: W A
authors.initials: WA
authors.lastname: Kudrle
authors.forename: S J
authors.initials: SJ
authors.lastname: Liu
authors.forename: J H
authors.initials: JH
authors.lastname: Charnov
authors.forename: B D
authors.initials: BD
authors.lastname: Butler
authors.forename: J H
authors.initials: JH
authors.lastname: Harris
mesh_terms: D000818:Animals; D006931:Hyperbaric Oxygenation; D008279:Magnetic Resonance Imaging; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013116:Spinal Cord / Q000473:pathology; D013119:Spinal Cord Injuries / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy