[Asthma and infection: interrelations].
The frequent interaction of infection in asthma is a result of a complex interrelationship. Infectious agents are capable both of inducing asthmatic crises and, at least for viruses, of initiating the asthmatic process. They also favour a specific IgE response to allergens. Similar immunity is involved in defence against these infectious agents but this immunity can be disturbed in asthmatic subjects; as seen with defects in immunoglobulin subclasses, disturbance in T lymphocyte function, monocytes and blood neutrophils. The determination of the genetic or acquired character of these disturbances is pre-condition for the development of a therapeutic substitute.
Gormand
F
F
Service de Pneumologie, Centre Hospitalier Lyon-Sud.
Pacheco
Y
Y
Perrin-Fayolle
M
M
D001249:Asthma / Q000276:immunology / Q000503:physiopathology*; D001424:Bacterial Infections / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D012141:Respiratory Tract Infections / Q000276:immunology / Q000503:physiopathology*; D014777:Virus Diseases / Q000503:physiopathology
Asthme et infection: interrelations.