title: [Management of cervico-vaginal dystrophies].
abstract: Fifty-nine outpatients affected by cervico-vaginal dystrophy with manifest symptoms were included in the study. Following initial tests (colposcopy with Schiller's test, colpocytological test, analysis of symptoms), a cycle of treatment was commenced using the insertion of a vaginal pessary of Polydeoxy-ribonucleotide (PDRN) in the evening for 20 days. A control on day 28 revealed a marked improvement of the symptoms together with a positive evolution of objective tests. During the 10th week after the end of therapy, both subjective and objective findings tended to confirm the relapse towards pre-treatment conditions.
authors.affiliation: Ospedale Maggiore, S. Giovanni Battista di Torino.
authors.forename: L
authors.initials: L
authors.lastname: Zagami
authors.forename: F
authors.initials: F
authors.lastname: Lesca
mesh_terms: D000287:Administration, Topical; D000368:Aged; D005260:Female; D006801:Humans; D008875:Middle Aged; D010570:Pessaries; D011089:Polydeoxyribonucleotides / Q000008:administration & dosage; D012008:Recurrence; D002577:Uterine Cervical Diseases / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D014623:Vaginal Diseases / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D014626:Vaginal Smears
chemical_list: D011089:Polydeoxyribonucleotides
vernacular_title: Contributo allo studio della terapia delle distrofie cervico-vaginali.