Micro-observation and characterization of bonding between bone and HA-glass-titanium functionally gradient composite.
Bioactive composite implants consisting of hydroxyapatite (HA)-glass (G) ceramic layer and Ti-6AI-4V alloy, so-called HA-G-Ti functionally gradient implant, were provided for investigating the bonding behaviour of bone to the implant in vivo. The HA-G-Ti composites were implanted in femur and tibia of dog for various periods (1-12 month). Microstructural appearance of the interface between bone and the HA-G coating layer as well as the transverse sections of the HA-G coating layer and further apposition of bone to the implant have been studied in detail with SEM. The ingress of collagen fibres into the HA-G coating layer and the deposit of apatite on the collagen fibres and HA crystal grains being containing within the HA-G coating layer have been observed. Radiographical experiments indicate that the reparative process in the bone tissue surrounding the implants is markedly ahead even at one month after implantation. FT-IR measurement and X-ray diffraction were carried out for studying the characterization of the calcified bone matrix around the implants and the new bone proliferated along the HA-G-coated face (surface).
Maruno
S
S
Nagoya Institute of Technology, Showa-ku, Nagoya, Japan.
Itoh
H
H
Ban
S
S
Iwata
H
H
Ishikawa
T
T
D000818:Animals; D001672:Biocompatible Materials; D003094:Collagen / Q000032:analysis; D004285:Dogs; D004548:Elasticity; D005269:Femur; D005583:Fourier Analysis; D005898:Glass / Q000032:analysis*; D006882:Hydroxyapatites / Q000032:analysis*; D008855:Microscopy, Electron, Scanning; D016348:Osseointegration; D019736:Prostheses and Implants; D013057:Spectrum Analysis; D013499:Surface Properties; D013977:Tibia; D014025:Titanium / Q000032:analysis*; D014961:X-Ray Diffraction
D001672:Biocompatible Materials; D006882:Hydroxyapatites; C070637:hydroxyapatite-glass-titanium composite; D003094:Collagen; D014025:Titanium