Pulmonary infiltrates with eosinophilia due to naproxen.
An increasing number of drugs have been implicated in the etiology of eosinophilic pneumonia characterized by the development of pulmonary infiltrates, and peripheral blood eosinophilia. Naproxen is a commonly used nonsteroidal anti-inflammatory drug which may be added to the growing list of pharmacologic agents associated with infiltrative pulmonary lesions. A case of eosinophilic pneumonia induced by Naproxen is described. The results of TBLB, a lymphocyte stimulation test, and a challenge test supported this diagnosis.
Ogawa
H
H
Department of Internal Medicine, Ishikawa Prefectural Central Hospital, Kanazawa, Japan.
Kurashima
K
K
Namura
M
M
Kanaya
H
H
Kawamura
Y
Y
Ohka
T
T
Kurumaya
H
H
Yasui
M
M
Fujimura
M
M
Matsuda
T
T
D000368:Aged; D001706:Biopsy; D004342:Drug Hypersensitivity / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008213:Lymphocyte Activation / Q000187:drug effects; D009288:Naproxen / Q000009:adverse effects* / Q000494:pharmacology / Q000627:therapeutic use; D010003:Osteoarthritis / Q000150:complications / Q000188:drug therapy; D011657:Pulmonary Eosinophilia / Q000139:chemically induced* / Q000473:pathology
D009288:Naproxen