Synthesis, antimicrobial, inotropic, and chronotropic activities of novel 1,2,4-triazolo[4,3-a]quinolines.
Starting from the 2-quinolylhydrazine 1 the title compounds were prepared according to Schemes 1 and 2. Some of them show activities described in the title of this paper.
Khalil
M A
MA
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Alexandria, Egypt.
Habib
N S
NS
Farghaly
A M
AM
el-Sayed
O A
OA
D000818:Animals; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis*; D001001:Anura; D001419:Bacteria / Q000187:drug effects; D002317:Cardiovascular Agents / Q000138:chemical synthesis*; D006339:Heart Rate / Q000187:drug effects; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests; D009200:Myocardial Contraction / Q000187:drug effects; D011804:Quinolines / Q000138:chemical synthesis* / Q000494:pharmacology; D014230:Triazoles / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D002317:Cardiovascular Agents; D011804:Quinolines; D014230:Triazoles