title: Neurosarcoidosis--demonstration of meningeal disease by gadolinium enhanced magnetic resonance imaging.
abstract: Arriving at a firm diagnosis of neurosarcoidosis continues to pose serious problems, particularly when evidence of granulomatous disease outside the nervous system is lacking. The commonest mode of presentation of neurosarcoidosis is with cranial nerve palsies. Two cases of presumed neurosarcoidosis with cranial nerve palsies showed clear evidence of focal meningeal disease on gadolinium-DTPA enhanced MRI brain scans. Although not specific for sarcoidosis, this technique may be very useful in aiding the diagnosis in suspected cases.
authors.affiliation: Department of Neuroradiology, Atkinson Morley's Hospital, London, UK.
authors.forename: K T
authors.initials: KT
authors.lastname: Khaw
authors.forename: H
authors.initials: H
authors.lastname: Manji
authors.forename: J
authors.initials: J
authors.lastname: Britton
authors.forename: F
authors.initials: F
authors.lastname: Schon
mesh_terms: D000368:Aged; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000175:diagnosis*; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008578:Meninges / Q000473:pathology*; D008875:Middle Aged; D009483:Neuropsychological Tests; D009942:Organometallic Compounds; D004369:Pentetic Acid; D012507:Sarcoidosis / Q000175:diagnosis*; D014390:Tuberculosis, Meningeal / Q000175:diagnosis
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA