title: An active feedback system for isotonic studies of smooth muscle.
abstract: A feedback system used to perform isotonic studies of smooth muscle is presented. This system is capable of applying a constant force to muscle samples regardless of their contractile activities. The force applied to the tissue is controlled using a proportional integral control system that drives a linear motor. The device is integrated into a sucrose gap tissue bath apparatus where measurements of displacement and electrical activity are also possible. The frequency of canine colonic smooth-muscle electrical oscillations is positively related to applied force.
authors.affiliation: Surgical Medical Research Institute, University of Alberta, Edmonton, Canada.
authors.forename: P J
authors.initials: PJ
authors.lastname: Sabourin
authors.forename: Y J
authors.initials: YJ
authors.lastname: Kingma
authors.forename: K L
authors.initials: KL
authors.lastname: Bowes
mesh_terms: D000818:Animals; D003106:Colon / Q000502:physiology; D004285:Dogs; D005246:Feedback / Q000502:physiology; D066298:In Vitro Techniques; D007551:Isotonic Contraction / Q000502:physiology*; D009130:Muscle, Smooth / Q000502:physiology*; D012016:Reference Values