title: Actuarial survival and other events following valve surgery in octogenarians: comparison with an age-, sex-, and race-matched population.
abstract: From January 1973 to December 1989, 54 patients over 80 years of age underwent an intracardiac repair which included a cardiac valve operation. There were 21 males and 33 females. Mean age at operation was 82 years, range 80-89 years. Fifty-two patients (96%) were in New York Heart Association functional class III or IV preoperatively. Six patients had undergone previous valve surgery (11%). There were eight hospital deaths (14.8%). Risk factors for hospital death included older age at repair (p = 0.008), increased total cardiopulmonary bypass time (p = 0.06), and, possibly, smaller aortic valve prosthesis (p = 0.10). All 46 hospital survivors were followed up at a mean of 28.8 months after hospital discharge. There were 11 late deaths (23.9%), occurring at a mean of 32.3 months postoperatively. Survival analysis indicated that increased age (p = 0.06) and increased pulmonary artery diastolic pressure preoperatively (p less than 0.07) were multivariate risk factors for overall mortality. Actuarial survival at 5 years was 44%, with no difference from survival in an age-, sex-, and race-matched population. We conclude that octogenarians in the modern era have good chance for survival following valvular surgery. As hazards for full anticoagulation were low in this series, if valve repair is not feasible, we presently recommend the use of mechanical valves in the elderly to reduce the requirement for late reoperation due to bioprosthesis degeneration.
authors.affiliation: Department of Surgery, Deborah Heart and Lung Center, Brown Mills, New Jersey.
authors.forename: L B
authors.initials: LB
authors.lastname: McGrath
authors.forename: M S
authors.initials: MS
authors.lastname: Adkins
authors.forename: C
authors.initials: C
authors.lastname: Chen
authors.forename: B M
authors.initials: BM
authors.lastname: Bailey
authors.forename: D
authors.initials: D
authors.lastname: Graf
authors.forename: J
authors.initials: J
authors.lastname: Fernandez
authors.forename: G W
authors.initials: GW
authors.lastname: Laub
authors.forename: S B
authors.initials: SB
authors.lastname: Pollock
mesh_terms: D000206:Actuarial Analysis; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002315:Cardiopulmonary Bypass / Q000401:mortality*; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000401:mortality*; D006801:Humans; D008297:Male; D012086:Reoperation; D013997:Time Factors; D044465:White People