title: Subependymoma with rhabdomyosarcomatous differentiation: report of a case and literature review.
abstract: A unique gliomesenchymal neoplasm, consisting of a subependymoma, a form of low-grade glioma, and a rhabdomyosarcoma, is described. It arose and recurred in the brain stem of a 52-year-old man. Immunohistochemical studies demonstrated the presence of a neuroectodermal marker S-100 protein within some sarcoma cells. The occurrence of this rare tumor supports the concept that striated muscle may derive from a neuroectodermal precursor lesion.
authors.affiliation: Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota.
authors.forename: F H
authors.initials: FH
authors.lastname: Tomlinson
authors.forename: B W
authors.initials: BW
authors.lastname: Scheithauer
authors.forename: P J
authors.initials: PJ
authors.lastname: Kelly
authors.forename: G S
authors.initials: GS
authors.lastname: Forbes
mesh_terms: D001932:Brain Neoplasms / Q000473:pathology*; D001933:Brain Stem / Q000473:pathology; D005910:Glioma / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D012208:Rhabdomyosarcoma / Q000473:pathology*