[Effect of rhizoma Zingiberis on anoxic or cooled mice].
The anti-anoxic experiments have indicated that the petroleum ether extract of Rhizoma Zingiberis can prolong the survival time in mice poisoned by KCN or under the condition of normobaric hypoxia, as well as decapitation-induced gasping duration in mice, but can not prolong the survival time in mice poisoned by NaNO4. The anti-anoxic action might be related to the reduction rate of O2 consumption of the body. The aqueous extract of Rhizoma Zingiberis does not possess the above-mentioned anti-anoxic action. Both extracts do not affect the survival time in cooled mice.
Zhang
M
M
Shen
Y
Y
Xu
Q
Q
D000818:Animals; D003080:Cold Temperature / Q000009:adverse effects*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology / Q000627:therapeutic use* / Q000633:toxicity; D005260:Female; D000860:Hypoxia / Q000188:drug therapy*; D008297:Male; D051379:Mice; D010101:Oxygen Consumption / Q000187:drug effects; D011041:Poisoning / Q000188:drug therapy; D011190:Potassium Cyanide / Q000506:poisoning; D012977:Sodium Nitrite / Q000506:poisoning
D004365:Drugs, Chinese Herbal; D012977:Sodium Nitrite; D011190:Potassium Cyanide