Lithium-TCA induced malignant syndrome. Case report.
1. The authors describe some adverse reactions, induced by lithium and TCA administration, in a 71 years old woman treated for mixed bipolar disturbance. 2. The case history here described, is perfectly compatible with a diagnosis of Malignant Hyperthermia (MH). 3. Utility of the association of hypothalamic phospholipid liposomes (HPL) and myorelaxants in the reduction of these lithium side effects, is discussed.
De Maio
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D
Servizio di Psichiatria-Lithium Center, Hospital Fatebenefratelli-Oftalmico, Milan, Italy.
Laviani
M
M
D000368:Aged; D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects* / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000150:complications / Q000188:drug therapy / Q000523:psychology; D005260:Female; D006801:Humans; D008081:Liposomes; D008094:Lithium / Q000009:adverse effects* / Q000627:therapeutic use; D008305:Malignant Hyperthermia / Q000188:drug therapy / Q000209:etiology*; D009125:Muscle Relaxants, Central / Q000627:therapeutic use; D010743:Phospholipids / Q000627:therapeutic use
D000929:Antidepressive Agents, Tricyclic; D008081:Liposomes; D009125:Muscle Relaxants, Central; D010743:Phospholipids; D008094:Lithium