title: [The diagnosis and therapy of recurrent tumor of the rectum].
abstract: The authors review the pathogenesis of locoregional recurrences of rectal cancer, pointing out clues for the diagnosis and staging of the disease which are valuable for the definition of a treatment strategy. Surgery is the mainstay of any attempt to cure those recurrences that are amenable to radical resection; over and above the diagnostic role of second-look laparotomy in suspected cases, surgery must include those measures able to reduce actinic damage whenever postoperative radiotherapy is required. On the other hand, palliative surgery is necessary to resolve the presence of intestinal obstruction, fistulous tract, or the removal of abscess and necrotic tissue. In these cases, the quality of life seems to be the prime factor in the choice of therapy (radiotherapy, loco-regional or systemic chemotherapy, hyperthermia).
authors.affiliation: Divisione di Oncologia Chirurgica, Istituto Nazionale per la Ricerca sul Cancro, Genova.
authors.forename: F
authors.initials: F
authors.lastname: Cafiero
authors.forename: M
authors.initials: M
authors.lastname: Gipponi
authors.forename: E
authors.initials: E
authors.lastname: Pirisi
authors.forename: S
authors.initials: S
authors.lastname: Bertoglio
authors.forename: L
authors.initials: L
authors.lastname: Moresco
authors.forename: M
authors.initials: M
authors.lastname: Spiccio
authors.forename: P
authors.initials: P
authors.lastname: Percivale
authors.forename: F
authors.initials: F
authors.lastname: Badellino
mesh_terms: D003131:Combined Modality Therapy / Q000379:methods; D006801:Humans; D008207:Lymphatic Metastasis; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D012004:Rectal Neoplasms / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D012007:Rectum / Q000601:surgery
vernacular_title: Considerazioni sulla diagnosi e terapia del tumore recidivo del retto.