Total-skin electron irradiation for cutaneous T-cell lymphoma: the Northern Israel Oncology Center experience.
Total-skin electron irradiation (TSEI) is effective and frequently used in the treatment of cutaneous T-cell lymphoma. A treatment technique has been developed at our center, using the Philips SL 75/10 linear accelerator. In our method, the patient is irradiated in a recumbent position by five pairs of uncollimated electron beams at a source to skin distance of 150 cm. This method provides a practical solution to clinical requirements with respect to uniformity of electron dose and low X-ray contamination. Its implementation does not require special equipment or modification of the linear accelerator, 19 of 23 patients (83%) with mycosis fungoides, treated by this method, achieved complete regression of their cutaneous lesions.
Kuten
A
A
Radiotherapy Unit, Northern Israel Oncology Center, Rambam Medical Center, Haifa.
Stein
M
M
Mandelzweig
Y
Y
Tatcher
M
M
Yaacov
G
G
Epelbaum
R
R
Rosenblatt
E
E
D000328:Adult; D000368:Aged; D002173:Cancer Care Facilities; D004583:Electrons; D005260:Female; D006801:Humans; D007557:Israel; D016410:Lymphoma, T-Cell, Cutaneous / Q000401:mortality / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D010315:Particle Accelerators; D011879:Radiotherapy Dosage; D012074:Remission Induction; D012878:Skin Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D014916:Whole-Body Irradiation / Q000009:adverse effects / Q000379:methods*