title: Preliminary experience with growth factor and porcine graft-young collagenous wettable membrane in the treatment of chronic diabetic ulcer.
abstract: Chronic ulcers are well-known complication of diabetes mellitus, often compounded by infection. Healing of lesions is problematic in some cases using conventional treatment. We have treated a group of six hospitalized diabetic patients with chronic ulcer by a combined regimen consisting of metabolic control, parenteral antibiotics, growth factor and porcine graft-young collagenous wettable membrane (YCWM) treatment. Five of our uncontrolled group had their ulcers improved at 87 +/- 37.6 hospital days after 45.8 +/- 20.2 days of growth factor and YCWM treatment. In conclusion, growth factor and porcine graft-YCWM therapy may be promising as an alternative choice in treatment of chronic diabetic ulcer.
authors.affiliation: Department of Internal Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan, R.O.C.
authors.forename: H C
authors.initials: HC
authors.lastname: Liao
authors.forename: H S
authors.initials: HS
authors.lastname: Huang
authors.forename: M J
authors.initials: MJ
authors.lastname: Huang
authors.forename: C C
authors.initials: CC
authors.lastname: Chen
mesh_terms: D000368:Aged; D000818:Animals; D001684:Biological Dressings; D002908:Chronic Disease; D048909:Diabetes Complications; D005260:Female; D005534:Foot Diseases / Q000628:therapy*; D006133:Growth Substances / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012883:Skin Ulcer / Q000628:therapy*; D013552:Swine
chemical_list: D006133:Growth Substances