Immunohistochemical expression of galactomannan in the cytoplasm of phagocytic cells during invasive aspergillosis.
The monoclonal antibody EB-A1 to galactomannan is apparently specific for detecting Aspergillus species and Penicillium marneffei in formalin-fixed, paraffin-embedded tissues. It reveals hyphae, remnants of filaments, and organisms in the cytoplasm of some phagocytic cells.
Piérard
G E
GE
Department of Dermatopathology, University of Liège, Belgium.
Arrese Estrada
J
J
Piérard-Franchimont
C
C
Thiry
A
A
Stynen
D
D
D000911:Antibodies, Monoclonal; D001228:Aspergillosis / Q000175:diagnosis*; D002473:Cell Wall / Q000737:chemistry; D003593:Cytoplasm / Q000737:chemistry; D003881:Dermatomycoses / Q000175:diagnosis*; D005690:Galactose / Q000031:analogs & derivatives; D006801:Humans; D007150:Immunohistochemistry; D008107:Liver Diseases / Q000175:diagnosis* / Q000382:microbiology; D008172:Lung Diseases, Fungal / Q000175:diagnosis*; D008351:Mannans / Q000032:analysis*; D010586:Phagocytes / Q000378:metabolism*
D000911:Antibodies, Monoclonal; D008351:Mannans; C012990:galactomannan; D005690:Galactose