[The Gemeprost test in the screening of endometrial pathology].
A randomized clinical trial has been performed to evaluate the efficacy of intravaginal 1 mg Gemeprost for pre-operative cervical dilatation prior to vacuum aspiration and curettage for endometrial biopsy. Eighty-nine patients were evaluated, 51 treated with Gemeprost and 38 with placebo: in the first group biopsy was possible in 94% of cases vs 86% in the second group. Pain was significantly reduced with Gemeprost improving the success rate and the patient compliance.
Fedele
M
M
Istituto di Ginecologia e Ostetricia, Universita di Torino.
Preve
C U
CU
Olivero
F
F
D'Affinito
S
S
Bontempo
S
S
D000527:Alprostadil / Q000031:analogs & derivatives*; D004107:Dilatation and Curettage; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D010919:Placebos; D011459:Prostaglandins E, Synthetic; D014591:Uterine Diseases / Q000175:diagnosis*
D010919:Placebos; D011459:Prostaglandins E, Synthetic; C021182:gemeprost; D000527:Alprostadil
Il Gemeprost nello screening della patologia endometriale.