title: Clinical trials with purified platelet releasate.
abstract: Clinical trials of PDWHF are ongoing and the final results are not yet available; however early lessons learned have allowed us to modify these trials. It is anticipated that the patient accrual will be completed within the next six months, and the last patient will complete the trial within the next year. At that time, we hope to have new insight into the role of PDWHF in the treatment of lower extremity ulcers. At this time, we are encouraged by the early improvement seen in patients entering the PDWHF versus saline trial. Preliminary results suggest that PDWHF improves the healing of diabetic ulcers of the lower extremity.
authors.affiliation: Department of Surgery and Dermatology, University of Pittsburgh, School of Medicine, PA.
authors.forename: D
authors.initials: D
authors.lastname: Steed
authors.forename: B
authors.initials: B
authors.lastname: Goslen
authors.forename: R
authors.initials: R
authors.lastname: Hambley
authors.forename: E
authors.initials: E
authors.lastname: Abell
authors.forename: P
authors.initials: P
authors.lastname: Hebda
authors.forename: M
authors.initials: M
authors.lastname: Webster
mesh_terms: D001792:Blood Platelets; D002908:Chronic Disease; D003929:Diabetic Neuropathies / Q000150:complications; D004311:Double-Blind Method; D006133:Growth Substances / Q000627:therapeutic use*; D006801:Humans; D007871:Leg Ulcer / Q000209:etiology / Q000628:therapy*; D011446:Prospective Studies; D014945:Wound Healing
chemical_list: D006133:Growth Substances