Prediction and prevention of IDDM--1991.
Although we can now identify some nondiabetic individuals who will subsequently develop clinical insulin-dependent diabetes mellitus (IDDM), our ability to predict subsequent clinical IDDM is far from perfect. In this article, we discuss the status of knowledge regarding the natural history of preclinical IDDM and discuss, especially in relation to predicting IDDM, the genetic, immunologic, and metabolic components of the IDDM disease process.
Palmer
J P
JP
Veterans Administration Medical Center, Medical Services, Seattle, WA 98108.
McCulloch
D K
DK
D015415:Biomarkers; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis* / Q000235:genetics / Q000517:prevention & control / Q000628:therapy; D005819:Genetic Markers; D006801:Humans
D015415:Biomarkers; D005819:Genetic Markers