title: [Two-year trial of the fluoride-containing varnishes Duraphat and Carex].
abstract: Previous studies have shown that topical application of the fluoride varnish Duraphat reduces caries incidence. The aim of the present study was to compare the caries inhibiting effect of a new fluoride varnish (Carex) containing 1.80% fluoride (F) with that of Duraphat (2.26%F). Informed consent was obtained from the guardians of 495 10-12-years-olds in Voss Dental Health District (low F area). The children were randomly allocated to two groups. One group of subjects received six-monthly applications of Duraphat (n = 206), the other Carex (n = 189). Ethical considerations precluded the use of a placebo varnish. All participants received dental examinations including one pair of posterior bitewing radiographs and necessary dental care annually. One trained examiner interpreted bitewing radiographs blindly. Total mean 2-year net DFS increment for 24 posterior approximal surfaces was 1.79 (s = 3.12) in the Duraphat group and 1.53 (s = 2.92) in the Carex group, a difference which was non-significant (P greater than 0.40). Thus it seems that Carex and Duraphat have approximately the same caries-preventive effect on posterior approximal surfaces.
authors.affiliation: Institutt for Samfunnsodontologi, Bergen.
authors.forename: A
authors.initials: A
authors.lastname: Nord
authors.forename: O
authors.initials: O
authors.lastname: Haugejorden
mesh_terms: D002648:Child; D003731:Dental Caries / Q000517:prevention & control*; D005260:Female; D005460:Fluorides, Topical / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010895:Pit and Fissure Sealants; D012969:Sodium Fluoride / Q000627:therapeutic use
chemical_list: C070175:Carex; D005460:Fluorides, Topical; D010895:Pit and Fissure Sealants; C023807:sodium fluoride topical preparation; D012969:Sodium Fluoride
vernacular_title: Kariesinsidens etter to års bruk av de fluoridholdige lakkene Duraphat og Carex.