[Clinical evaluation of cefpirome in pediatric field].
Cefpirome (CPR), a new synthetic cephalosporin antibiotic, was administered to 10 patients with infectious diseases. The patients included 5 boys and 5 girls from 1 month to 5 years of age. They were given the drug intravenously at dosages ranging 53-100 mg/kg/day for 4 to 10 days. Clinical efficacy was evaluated in 9 patients: excellent in 2 patients, good in 6 patients and fair in 1 patient. The overall efficacy rate was 88.9%. No adverse effects were observed except in one patient who showed a slight increase of serum GOT and GPT.
Matsuoka
S
S
Department of Pediatrics, School of Medicine, Tokushima University.
Takahashi
Y
Y
Kuroda
Y
Y
D000208:Acute Disease; D000367:Age Factors; D002511:Cephalosporins / Q000008:administration & dosage* / Q000627:therapeutic use; D002675:Child, Preschool; D003092:Colitis / Q000188:drug therapy* / Q000382:microbiology; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007223:Infant; D007275:Injections, Intravenous; D008297:Male; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000382:microbiology; D000097572:Cefpirome
D002511:Cephalosporins; D000097572:Cefpirome