title: What's old and new in molecular phylogenetics.
abstract: While it is fairly easy to devise a phylogenetic tree based on molecular data, it has proven difficult to tell how reliable any such tree is. Thus while the genetic inference that humans, chimpanzees, and gorillas cluster together is widely accepted, the genetic inference that the primary division among Old World human populations is between Asia and EurAfrica is not. A molecular phylogenetic inference linking humans and chimpanzees was proposed in the 1980s based on the technique of DNA hybridization. Despite several recent publications in primary and secondary source material, much confusion still exists surrounding the work. This paper tries to clarify issues that may still be confusing to physical anthropologists, and proposes criteria upon which to judge the robusticity of a phylogenetic inference based on DNA hybridization, in light of a recent published claim of replication. The claim of replication is considered critically. Interestingly, the original DNA hybridization data may actually show a chimp-gorilla link, in harmony with other phylogenetic results.
authors.affiliation: Department of Anthropology, Yale University, New Haven, Connecticut 06520.
authors.forename: J
authors.initials: J
authors.lastname: Marks
mesh_terms: D000818:Animals; D004247:DNA / Q000032:analysis*; D006801:Humans; D009693:Nucleic Acid Hybridization; D010802:Phylogeny; D011323:Primates / Q000145:classification*
chemical_list: D004247:DNA