title: Age-related complications and optimal choice of artificial heart valves in elderly patients.
abstract: The use of bioprosthetic heart valves in elderly patients is presently advocated by many since implanting mechanical valves are considered to result in unacceptable rates of thromboembolism and bleeding. However the somewhat limited durability of bioprostheses has to be acknowledged since a group of elderly patients will eventually require a reoperation due to tissue failure. We have evaluated our policy to implant mechanical heart valve prostheses even in elderly patients based on the conception that we believe that anticoagulation in this group of patients can be handled with a low rate of complications.
authors.affiliation: Department of Thoracic Surgery, University Hospital, Lund, Sweden.
authors.forename: L I
authors.initials: LI
authors.lastname: Thulin
mesh_terms: D000367:Age Factors; D000925:Anticoagulants / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis / Q000009:adverse effects* / Q000401:mortality / Q000706:statistics & numerical data; D006470:Hemorrhage / Q000453:epidemiology / Q000401:mortality; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology* / Q000401:mortality; D011474:Prosthesis Design; D013548:Sweden / Q000453:epidemiology; D013923:Thromboembolism / Q000453:epidemiology / Q000401:mortality
chemical_list: D000925:Anticoagulants