title: [Radiotherapy of solitary and multiple eosinophilic granulomas of bone (stage I)].
abstract: Between 1957 and 1990 15 patients with solitary (stage Ia by Greenberger) and 2 patients with multiple (stage Ib) eosinophilic granuloma of the bone were treated by radiotherapy in 18 locations after previous surgery. The doses applied varied from 6 Gy to 42 Gy (median for patients under 18 years: 8 Gy, for patients over 18 years: 30 Gy). Median follow-up was 9 years (range, 0.3-33 years). Local control rate and survival were 100%. Three patients with granuloma developed a second granuloma within 13 years after primary diagnosis (two bone manifestations, one cutaneous manifestation). Long-term follow-up of patients with solitary eosinophilic granuloma is necessary.
authors.affiliation: Abteilung für Strahlentherapie, Universitätsklinik Hamburg-Eppendorf.
authors.forename: T
authors.initials: T
authors.lastname: Wiegel
authors.forename: K
authors.initials: K
authors.lastname: Sommer
authors.forename: J
authors.initials: J
authors.lastname: Knop
authors.forename: M
authors.initials: M
authors.lastname: Reuter
authors.forename: M
authors.initials: M
authors.lastname: Baumann
authors.forename: A
authors.initials: A
authors.lastname: Krüll
authors.forename: K H
authors.initials: KH
authors.lastname: Hübener
mesh_terms: D000293:Adolescent; D000328:Adult; D001847:Bone Diseases / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy; D001859:Bone Neoplasms / Q000473:pathology* / Q000532:radiotherapy; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004803:Eosinophilic Granuloma / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D011182:Postoperative Care; D011879:Radiotherapy Dosage; D012878:Skin Neoplasms / Q000556:secondary
vernacular_title: Strahlentherapie des solitären und multiplen eosinophilen Granuloms des Knochens (Stadium I).