Congenital giant pigmented nevus presenting in one identical twin.
A case of congenital giant pigmented nevus in only one of identical twins confirmed by results of DNA print marker testing is discussed. The benign lesion was removed by serial excision over a five-year period, with excellent results. Current concepts in pathogenesis and genetics are reviewed. We conclude that there is evidence for both genetic and nongenetic causes of congenital giant pigmented nevi.
Morganroth
G S
GS
Department of Dermatology, University of Michigan, Ann Arbor.
Taylor
R S
RS
Izenberg
P H
PH
D004200:Diseases in Twins; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009508:Nevus, Pigmented / Q000151:congenital* / Q000235:genetics / Q000473:pathology; D014430:Twins, Monozygotic