Dietary sources of N-nitrosamines in a high-risk area for oesophageal cancer--Kashmir, India.
Samples of foods consumed frequently in Kashmir, a high-risk area for oesophageal cancer, were analysed for the presence of volatile N-nitrosamines. Relatively high levels of N-nitrosodimethylamine (NDMA), N-nitrosopiperidine (NPIP) and N-nitrosopyrrolidine (NPYR) were detected in smoked fish (20 micrograms/kg NDMA), sun-dried spinach (5.8 micrograms/kg NDMA; 23.8 micrograms/kg NPIP), sun-dried pumpkin (24.6 micrograms/kg NPYR) and dried, mixed vegetables (10 micrograms/kg NDMA). The possible role of N-nitrosamines in the etiology of oesophageal cancer in Kashmir is discussed.
Siddiqi
M A
MA
Department of Biochemistry, University of Kashmir, Srinagar, India.
Tricker
A R
AR
Kumar
R
R
Fazili
Z
Z
Preussmann
R
R
D004032:Diet; D004938:Esophageal Neoplasms / Q000209:etiology*; D005504:Food Analysis; D006801:Humans; D007194:India; D009602:Nitrosamines / Q000032:analysis / Q000633:toxicity*; D012307:Risk Factors; D014835:Volatilization
D009602:Nitrosamines