title: Deficiency of IgG subclasses and IgA, and elevation of IgE in children with a past history of bacterial meningitis.
abstract: Of 44 children who recovered from an attack of bacterial meningitis, 3 (7%) were found to have IgG subclass deficiency, 5 (11%) had IgA deficiency and 22 (50%) had raised IgE levels. These results suggest that immunoglobulin abnormalities may be an important predisposing factor in some cases of bacterial meningitis.
authors.affiliation: Department of Child Health, University of Queensland, Mater Children's Hospital, South Brisbane, Australia.
authors.forename: R K
authors.initials: RK
authors.lastname: Loh
authors.forename: Y H
authors.initials: YH
authors.lastname: Thong
authors.forename: A
authors.initials: A
authors.lastname: Ferrante
mesh_terms: D001424:Bacterial Infections / Q000150:complications / Q000276:immunology* / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D004406:Dysgammaglobulinemia / Q000209:etiology / Q000276:immunology* / Q000378:metabolism; D005260:Female; D006801:Humans; D017098:IgA Deficiency; D017099:IgG Deficiency; D007073:Immunoglobulin E / Q000378:metabolism*; D007223:Infant; D008297:Male; D008581:Meningitis / Q000150:complications / Q000276:immunology* / Q000378:metabolism
chemical_list: D007073:Immunoglobulin E