Devitalizing effects of phenol on bone marrow cells. Histologic study on cadaveric animal vertebrae.
The devitalizing effects of 5-90 percent phenol for 30 seconds on bone marrow cells were examined on vertebral bodies of fresh animal cadavers. Evaluation was made by measuring the width of the zone of necrotic cells. The zone increased with rising phenol concentration up to 75 percent, reaching an average width of 0.75 mm. However, when protected by bone trabeculae, the cells escaped devitalization.
Lang
S
S
University of Vienna Bone Tumor Register, Pathologic-Anatomical Institute, Vienna, Austria.
Lack
W
W
Brand
G
G
Salzer-Kuntschik
M
M
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects / Q000473:pathology; D001854:Bone Marrow Cells; D002417:Cattle; D002470:Cell Survival / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D009336:Necrosis / Q000139:chemically induced; D019800:Phenol; D010636:Phenols / Q000008:administration & dosage / Q000494:pharmacology*; D013552:Swine
D010636:Phenols; D019800:Phenol