Contrast agents and cerebral hemodynamics.
Contrast-enhanced magnetic resonance imaging of regional cerebral hemodynamics is discussed. Techniques for measuring cerebral blood volume (CBV) have been validated in animal models and have recently been applied to human studies. Factors affecting CBV measurement in pathologic tissue are addressed. Extension of these techniques to the measurement of cerebral blood flow is presented.
Rosen
B R
BR
MGH-NMR Center, Department of Radiology, Massachusetts General Hospital, Boston.
Belliveau
J W
JW
Buchbinder
B R
BR
McKinstry
R C
RC
Porkka
L M
LM
Kennedy
D N
DN
Neuder
M S
MS
Fisel
C R
CR
Aronen
H J
HJ
Kwong
K K
KK
D001810:Blood Volume; D001812:Blood-Brain Barrier; D002560:Cerebrovascular Circulation / Q000502:physiology*; D003287:Contrast Media; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods
D003287:Contrast Media