title: [Pathogenesis and morphogenesis of acute pulmonary insufficiency during blood loss].
abstract: Postmortem clinical and anatomic lung examinations in patients dead of blood loss and the experiments on animals have shown that pathological changes underlying acute pulmonary failure are to a great extent due to disorders in pulmonary hemodynamics associated with the spasm in the arterial and venous vascular bed of the respiratory zone. Durable spasm of pulmonary veins promotes to hydrostatic pressure elevation and the onset of pulmonary edema even after blood loss replacement. Massive infusion-transfusion therapy performed in pulmonary hemodynamic disorders may aggravate pulmonary edema and lead to the onset of acute pulmonary failure.
authors.forename: I V
authors.initials: IV
authors.lastname: Timofeev
authors.forename: V G
authors.initials: VG
authors.lastname: Brialin
authors.forename: N D
authors.initials: ND
authors.lastname: Klochkov
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000818:Animals; D004285:Dogs; D006470:Hemorrhage / Q000150:complications*; D006801:Humans; D008168:Lung / Q000473:pathology*; D009024:Morphogenesis; D012131:Respiratory Insufficiency / Q000209:etiology* / Q000473:pathology
vernacular_title: Patogenez i morfogenez ostroĭ legochnoĭ nedostatochnosti pri krovopotere.