[Insulin-inducible structural reorganizations in the lipid bilayer of fatty tissue plasma membranes and their age-related characteristics].
Effect of insulin on properties of plasmatic membranes (PM) from adipose tissue of young and aged rats has been studied. Insulin increased the anisotropy of PM. The data obtained indicate that this effect of insulin was specific and was confined to specific domains of the membrane matrix. Both the level of insulin-induced structural changes in PM and fluidity of lipid bilayer decreased with age.
Egutkin
G G
GG
Gatsko
G G
GG
D000273:Adipose Tissue / Q000187:drug effects* / Q000648:ultrastructure; D000375:Aging / Q000187:drug effects*; D000818:Animals; D002462:Cell Membrane / Q000187:drug effects / Q000648:ultrastructure; D004305:Dose-Response Relationship, Drug; D005454:Fluorescence Polarization; D007328:Insulin / Q000494:pharmacology*; D008051:Lipid Bilayers / Q000737:chemistry*; D008297:Male; D008560:Membrane Fluidity / Q000187:drug effects; D008563:Membrane Lipids / Q000737:chemistry*; D051381:Rats
D007328:Insulin; D008051:Lipid Bilayers; D008563:Membrane Lipids
Indutsiruemye insulinom strukturnye perestroĭki lipidnogo bisloia plazmaticheskikh membran zhirovoĭ tkani i ikh vozrastnye osobennosti.