title: Mixed transcortical aphasia: clinical features and neuroanatomical correlates. A possible role of the right hemisphere.
abstract: This paper reports the clinical features of 2 patients affected by mixed transcortical aphasia. Both of them had extensive damage of the left hemisphere. Cerebral blood flow measurement showed a marked decrease in left-hemisphere flow. In particular, speech areas were found to be morphologically and functionally damaged. The present findings, together with a critical review of the literature, served as a starting point for a discussion of linguistic features, diagnostic criteria and classical neuroanatomical interpretation of mixed transcortical aphasia. The possible contribution of the right hemisphere in determining this aphasic syndrome is suggested.
authors.affiliation: II Clinica Neurologica, II Facoltà di Medicina, Napoli, Italia.
authors.forename: D
authors.initials: D
authors.lastname: Grossi
authors.forename: L
authors.initials: L
authors.lastname: Trojano
authors.forename: L
authors.initials: L
authors.lastname: Chiacchio
authors.forename: A
authors.initials: A
authors.lastname: Soricelli
authors.forename: L
authors.initials: L
authors.lastname: Mansi
authors.forename: A
authors.initials: A
authors.lastname: Postiglione
authors.forename: M
authors.initials: M
authors.lastname: Salvatore
mesh_terms: D000368:Aged; D001037:Aphasia / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D002540:Cerebral Cortex / Q000473:pathology; D002560:Cerebrovascular Circulation; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D015899:Tomography, Emission-Computed, Single-Photon