[Circulating immune complexes and neutrophilic phagocytic function in patients with idiopathic autoimmune thrombocytopenic purpura].
The concentration of circulating immune complexes, serum immunoglobulins and state of phagocytic function of neutrophils was studied in patients with autoimmune thrombocytopenic purpura. The patients showed a significant increase of the levels of circulating immune complexes, content of Ig M and Ig G, an increase of the phagocytic activity of neutrophils at the stage of migration, adhesion and absorption of the heterogeneous. The revealed disorders of phagocytic function and destruction of granulocytes at the stage of digestion may be explained by increased load on the phagocytic neutrophils due to the main pathologic process.
Tishchenko
L M
LM
Volobueva
Z V
ZV
D000328:Adult; D000936:Antigen-Antibody Complex / Q000097:blood*; D001327:Autoimmune Diseases / Q000276:immunology*; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology*; D010587:Phagocytosis / Q000276:immunology*; D011696:Purpura, Thrombocytopenic / Q000276:immunology*
D000936:Antigen-Antibody Complex; D007136:Immunoglobulins
Tsirkuliruiushchie immunnye kompleksy i fagotsitarnaia funktsiia neĭtrofilov u bol'nykh idiopaticheskoĭ autoimmunnoĭ trombotsitopenicheskoĭ purpuroĭ.