Resistance of the embryonic notochord to invasion by malignant neurogenic tumor cells in vitro.
Very few tissues in vivo are resistant to invasion by malignant cells. In this paper, confrontation cultures consisting of chick embryonic notochord fragments and cell aggregates from three malignant neurogenic cell lines showed a resistance of the embryonic organ to malignant invasion by tumor cells. The mechanism of resistance remains unclear.
Schroyens
W
W
Department of Hematology and Oncology, J.-Liebig University, Giessen, Germany.
Camon
J
J
De Ridder
L
L
D000818:Animals; D002356:Cartilage / Q000196:embryology / Q000473:pathology; D002642:Chick Embryo; D003094:Collagen / Q000378:metabolism; D009361:Neoplasm Invasiveness; D009672:Notochord / Q000473:pathology*; D014407:Tumor Cells, Cultured
D003094:Collagen