title: [Chronic hypoparathyroidism: review of 5 clinical cases].
abstract: In 5 patients with a long clinical evolution of tetany and/or convulsions and with documented hypocalcaemia and hyperphosphatemia, low or inappropriate values of parathormone were detected. Only two of the patients had a history of subtotal thyroidectomy and all presented with basal ganglia calcification, bilateral subcapsular cataracts and prolonged QTc interval in the ECG. After one month of oral therapy with calcium and calcitriol, the values of calcaemia and phosphatemia were in a near-normal range with the exception of a patient in which that normalization was much slower and only occurred after correction of magnesaemia. In this last patient statistical correlation between QTc interval in the ECG and the calcaemia was statistically significant (P less than 0.001). We conclude that the QTc interval can be a useful and accessible index in acute situations of symptomatic hypocalcaemia.
authors.affiliation: Unidade de Endocrinologia, Hospital Curry Cabral, Lisboa.
authors.forename: J
authors.initials: J
authors.lastname: Anselmo
authors.forename: J
authors.initials: J
authors.lastname: Martins
authors.forename: L
authors.initials: L
authors.lastname: Matos
authors.forename: J
authors.initials: J
authors.lastname: Boavida
authors.forename: F
authors.initials: F
authors.lastname: Carreiras
authors.forename: G
authors.initials: G
authors.lastname: Correia
authors.forename: F
authors.initials: F
authors.lastname: Lima e Silva
authors.forename: E
authors.initials: E
authors.lastname: Pereira
authors.forename: J C
authors.initials: JC
authors.lastname: Corrêa
mesh_terms: D000328:Adult; D002908:Chronic Disease; D005260:Female; D006801:Humans; D006996:Hypocalcemia / Q000209:etiology; D007011:Hypoparathyroidism / Q000150:complications / Q000378:metabolism* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged
vernacular_title: Hipoparatiroidismo crónico: revisão de 5 casos clínicos.