[Morphometric features of breast cancer cells in the evaluation of the degree of tumor differentiation].
Morphometric study of the cell and nucleus surface as well as nucleus-cytoplasmatic ratio are performed in 80 patients with mammary carcinoma using a Soviet cytoanalyzer "Integral-2MT". Highly differentiated carcinomas are characterized by a domination (61.3%) of small nuclei (up to 120 microns 2). Moderately differentiated carcinomas are polymorphic by their composition: 43.3% nuclei up to 120 microns 2, 39.3% from 120 to 160 microns 2, remaining nuclei are of a large size. Poorly differentiated carcinomas are even more polymorphic due to high percentage of large nuclei--from 140 to 200 microns 2 and larger representing 46.5% cells. The analysis of nuclear size distribution allows estimation of the degree of cell differentiation in the tumour.
Sil'chenko
S A
SA
Loboda
V I
VI
Isakova
L M
LM
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology*; D002454:Cell Differentiation / Q000502:physiology; D002467:Cell Nucleus / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged
Morfometricheskie osobennosti kletok raka molochnoĭ zhelezy v otsenke stepeni differentsirovki opukholi.