[A control study of clomipramine and amitriptyline for treating obsessive-compulsive disorder].
This paper reported a comparative study of clomipramine (n = 21) and amitriptyline (n = 18) for treatment OCD. The improvement rate of clomipramine and amitriptyline was 95.2% and 55.6%, respectively (P less than 0.01). The decreased scores of obsessive-compulsive and depressive factors of SCL-90 of clomipramine were higher than amitriptyline. The results showed that clomipramine has better therapeutic effects and less side-effects than amitriptyline.
Zhao
J P
JP
Mental Health Institute of Hunan Medical University, Changsha.
D000293:Adolescent; D000328:Adult; D000639:Amitriptyline / Q000627:therapeutic use*; D002997:Clomipramine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy*
D000639:Amitriptyline; D002997:Clomipramine