title: Effect of clomiphene citrate upon periovulatory endometrial development in the baboon.
abstract: Endometrial histology in baboons (Papio cynocephalus anubis) was evaluated after five days of clomiphene citrate (CC) treatment initiated on either cycle day six (n = 8) or ten (n = 4). Biopsies performed before and after a human chorionic gonadotropin (hCG) induced ovulation were compared to non-CC treated controls. Although CC had a definite antiestrogenic effect on perineal skin, no significant effect of endometrial proliferation was demonstrable.
authors.affiliation: Institute of Primate Research, National Museums of Kenya, Nairobi.
authors.forename: R M
authors.initials: RM
authors.lastname: Eley
authors.forename: K G
authors.initials: KG
authors.lastname: Gould
authors.forename: D S
authors.initials: DS
authors.lastname: Eley
authors.forename: M A
authors.initials: MA
authors.lastname: Suleman
authors.forename: R P
authors.initials: RP
authors.lastname: Tarara
mesh_terms: D000818:Animals; D001707:Biopsy, Needle / Q000662:veterinary; D002996:Clomiphene / Q000494:pharmacology*; D004717:Endometrium / Q000187:drug effects* / Q000254:growth & development / Q000648:ultrastructure; D005260:Female; D008183:Luteal Phase; D008597:Menstrual Cycle; D008855:Microscopy, Electron, Scanning; D010060:Ovulation; D010215:Papio / Q000502:physiology*; D010502:Perineum; D012867:Skin / Q000187:drug effects
chemical_list: D002996:Clomiphene