[The functional activity of the urethral neutrophilic granulocytes in patients with chronic urethroprostatitis and its correction].
The functional state of urethral neutrophil granulocytes in patients with chronic urethro-prostatitis, and possibility of miramistin use in complex treatment of the disease were investigated. The data revealed functional suppression of these granulocytes in the patients. Complex treatment with miramistin normalized indices of urethral phagocytic activity, on the contrary, after treatment of the patients without the agent there was no tendency to normalize urethral phagocytic function. The findings suggest that miramistin supplemented to routine antiinflammatory therapy improves curative results in patients with chronic urethro-prostatitis but the drug should be prescribed in accordance with the initial function of urethral neutrophil granulocytes.
Vozianov
A F
AF
Krivoshein
Iu S
IuS
Pasechnikov
S P
SP
Kovalenko
V V
VV
Shatrov
V A
VA
Kuznetsova
L V
LV
D000328:Adult; D000368:Aged; D000892:Anti-Infective Agents, Urinary / Q000009:adverse effects / Q000627:therapeutic use; D001548:Benzalkonium Compounds / Q000009:adverse effects / Q000627:therapeutic use; D002908:Chronic Disease; D004341:Drug Evaluation; D006801:Humans; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000187:drug effects / Q000276:immunology*; D011472:Prostatitis / Q000188:drug therapy / Q000276:immunology*; D014521:Urethra / Q000276:immunology*; D014526:Urethritis / Q000188:drug therapy / Q000276:immunology*
D000892:Anti-Infective Agents, Urinary; D001548:Benzalkonium Compounds; C058048:miramistin
Funktsional'naia aktivnost' uretral'nykh neĭtrofil'nykh granulotsitov u bol'nykh khronicheskim uretroprostatitom i ee korrektsiia.