Cutaneous afferent activity in the median nerve during grasping in the primate.
Neural activity was recorded from the median nerve of a monkey during grasping and lifting, using a chronically implanted cuff electrode. At the onset of lifting, there was an initial dynamic response during which the intensity of the neural signal increased rapidly. This neural response attained its peak value well before the displacement, the load force or the grip force. The time course and peak of the rectified, integrated neurogram were best correlated with the rate of change of grip force. The neural activity declined exponentially to a steady value following the initial peak. During steady holding the mean amplitude of the neurogram was best correlated with the mean grip force. At the end of the holding phase there was a short burst of neural activity as the monkey relaxed the grip force and released the object. During some blocks of trials pulse perturbations were applied to the object. When the monkey did not increase the grip force in advance of the perturbation, the perturbation produced a relatively large displacement of the object and a burst of neural activity whose onset coincided with the onset of displacement. When the monkey anticipated the perturbation by increasing the grip force during the holding period preceding the perturbation, the perturbation produced a relatively small displacement and relatively little increase in neural activity.
Milner
T E
TE
Centre de recherche en sciences neurologiques, Université de Montréal, Canada.
Dugas
C
C
Picard
N
N
Smith
A M
AM
D000344:Afferent Pathways / Q000502:physiology*; D000818:Animals; D004576:Electromyography; D005260:Female; D008252:Macaca fascicularis; D008475:Median Nerve / Q000502:physiology*; D009132:Muscles / Q000294:innervation*; D009474:Neurons / Q000502:physiology*; D005082:Physical Exertion; D012044:Regression Analysis; D012867:Skin / Q000294:innervation*