[Experience in long-term clofelin use in the treatment of glaucoma].
A long (4-14 years, the mean period 7.8 +/- 1.5) follow-up of 52 patients with primary open-angle glaucoma, regularly administered clofelin instillations (over the entire follow-up) has demonstrated a manifest hypotensive and a good functional result of such therapy. Despite reduction of systemic arterial pressure induced by clofelin instillations, rheo-ophthalmography has shown enhanced blood stream in ocular vessels. 52 percent of patients were administered no miotics but only clofelin (16 patients, 28 eyes) or clofelin+timolol (11 patients, 17 eyes).
Ermakova
V N
VN
Kondé
L A
LA
Davydova
N G
NG
D000368:Aged; D000369:Aged, 80 and over; D003000:Clonidine / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D013997:Time Factors; D013999:Timolol / Q000008:administration & dosage
D013999:Timolol; D003000:Clonidine
Opyt dlitel'nogo primeneniia klofelina v terapii glaukomy.