[Experimental and clinical study of tong jing bao and Angelicae complex injection in treating fallopian tube obstruction].
Twenty-two female rabbits with fallopian tube obstruction as the model, were made by 25% Phenol-Tragacanth Mucilage in the laboratory study. Eight rabbits were treated by taking Tong Jing Bao and giving transcervical intrauterine injecting of Angelicae complex injection. Seven were treated with the latter and other seven with 0.9% saline only as the control group. The study showed that in the opening fallopian tube, anti-inflammation, limiting the hyperplasia of fibro-connective tissue and improving the regeneration of epithelial tissue, the first group was more effective than the other two groups (P less than 0.05). Forty-eight infertile women, in whom the fallopian tube obstruction were proved by hysterosalpingography, were divided into two groups for the clinical study. Thirty patients were treated as same as the first group of rabbits. As the control group, other eighteen women were treated with transcervical intrauterine injecting of gentamycin and 0.9% saline in 3 to 6 months. The effective rates were 94.6% and 56.6% (P less than 0.01) and the subsequent pregnancy rates were 46.7% and 27.8% respectively in the different two groups.
Lian
F
F
Nanjing College of TCM.
Sun
N Q
NQ
Xia
G C
GC
D000328:Adult; D000818:Animals; D003251:Constriction, Pathologic / Q000188:drug therapy; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005184:Fallopian Tube Diseases / Q000188:drug therapy*; D005186:Fallopian Tube Patency Tests; D005260:Female; D006801:Humans; D011817:Rabbits; D012488:Salpingitis / Q000150:complications
D004365:Drugs, Chinese Herbal