[Effect of mutant genes db(diabetes) and m(misty) on the severity of high-dose streptozotocin diabetes in C57bl/KsJY mice].
It is stated that high-dose streptozotocin diabetes is more serious in gene db-homozygous mice of mutant line C57BL/KsJY than in heterozygotes db +/+ m and mice M+/+m. Manifestation of spontaneous insulin-independent diabetes mellitus in homozygotes db decreases the level of hyperglycemic streptozotocin-induced reactions.
Blokh
K O
KO
Poltorak
V V
VV
Brindak
O I
OI
D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000235:genetics*; D006579:Heterozygote; D006720:Homozygote; D008297:Male; D051379:Mice; D008817:Mice, Mutant Strains; D009154:Mutation; D012720:Severity of Illness Index
Vliianie mutantnykh genov db(diabetes) i m(misty) na tiazhest' vysokodozovogo streptozototsinovogo diabeta u mysheĭ linii C57bl/KsJY.