[A case of lacrimal gland malignant lymphoma, associated with Sjögren's syndrome].
A 64 year-old female complained of left upper lid swelling. Painless mass lesions were found in her bilateral lacrimal gland areas. She also complained of a dry sensation in both eyes and her mouth. The rose bengal test, Schirmer's test and fluorescein dye test were positive. Lip biopsy revealed chronic sialoadenitis and rheumatoid factor titer was elevated. Anti-nuclear and anti-RNP antibodies were positive. Anti-SS-A and anti-SS-B antibodies were both negative. Left pre-and post auricular, cervical and inguinal lymph nodes were palpable. Excisional biopsies of bilateral orbital lesions and an inguinal lymph node revealed the presence of reactive lymphoid hyperplasia in the right orbit, and B cell type, diffuse, large cell lymphoma, in the left orbit and inguinal lymph node. Intensive chemotherapy resulted in complete remission. Lacrimal gland lymphoma must be considered when examining cases of Sjogren's syndrome.
Ohshima
K
K
Department of Ophthalmology, Okayama University Medical School, Japan.
Matsuo
N
N
Yokoe
S
S
Yoshino
T
T
Akagi
T
T
D005134:Eye Neoplasms / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D007766:Lacrimal Apparatus Diseases / Q000150:complications* / Q000473:pathology; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000473:pathology; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000150:complications*