Theory of low-frequency vibrations in DNA macromolecules.
To describe low-frequency dynamics of DNA macromolecules a model is developed taking into account the hydrogen bond stretching in base pairs, the backbone flexibility and intranucleoside mobility. For double-stranded DNA the normal vibrations are found and the structure of low-frequency spectrum is determined. The agreement between theory and Raman spectroscopy data for B-DNA is demonstrated. Conformational dependences of vibration spectrum during the B----A and helix----coil DNA transitions are studied. The contribution coming from low-frequency mobility to the nucleic-protein recognition processes is discussed.
Volkov
S N
SN
Institute for Theoretical Physics, Academy of Sciences of the Ukrainian SSR, Kiev.
Kosevich
A M
AM
D004247:DNA / Q000737:chemistry*; D006860:Hydrogen Bonding; D046911:Macromolecular Substances; D008433:Mathematics; D008956:Models, Chemical; D009690:Nucleic Acid Conformation; D013059:Spectrum Analysis, Raman; D013816:Thermodynamics; D014732:Vibration
D046911:Macromolecular Substances; D004247:DNA