title: [Thrombolytic therapy in acute myocardial infarction at the pre-hospital stage].
abstract: Mobile teams of the Leningrad Emergency Station came to use prehospital thrombolytic therapy (TT) for acute myocardial infarction (AMI) in 1986. The trial reported includes three groups of AMI patients: group I of 67 patients received avelysin in a dose of 0.5 mln FU, group II of 35 patients received celyase in a dose of 1 mln FU, group III consisted of 47 control subjects. The analysis of the treatment results showed that intravenous infusion of avelysin enabled myocardial reperfusion in 49.3% of cases while that of celyase in 5.7% (noninvasive data). High effectiveness of avelysin is inferred as well as safety of systemic TT at prehospital stage of AMI.
authors.forename: S Iu
authors.initials: SIu
authors.lastname: Varshavskiĭ
authors.forename: S Kh
authors.initials: SKh
authors.lastname: Fel'dman
authors.forename: K V
authors.initials: KV
authors.lastname: Zhuravlev
authors.forename: M V
authors.initials: MV
authors.lastname: Borisov
authors.forename: O A
authors.initials: OA
authors.lastname: Loginovskaia
mesh_terms: D000328:Adult; D004359:Drug Therapy, Combination; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D005392:First Aid; D006493:Heparin / Q000008:administration & dosage*; D006801:Humans; D007262:Infusions, Intravenous; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D013300:Streptokinase / Q000008:administration & dosage*; D015912:Thrombolytic Therapy
chemical_list: D005343:Fibrinolytic Agents; D006493:Heparin; D013300:Streptokinase
vernacular_title: Tromboliticheskaia terapiia pri ostrom infarkte miokarda na dogospital'nom étape.