title: [Course of dilatative hypertrophic cardiomyopathy].
abstract: Five patients with hypertrophic cardiomyopathy developed left-ventricular dilatation and congestive heart failure during an observation period of 16-29 years. In one patient cardiac transplantation had to be performed. The initial predominant symptoms of outflow-tract obstruction and diastolic dysfunction developed into progressive left-ventricular systolic failure. The question of whether this is a well-defined subgroup of patients with hypertrophic cardiomyopathy, or whether hypertrophic cardiomyopathy turns into a phase of left-ventricular dilatation and failure after some years remains to be elucidated by long-term studies.
authors.affiliation: Abt. für Kardiologie, Zentrum Innere Medizin, Universität Frankfurt.
authors.forename: A
authors.initials: A
authors.lastname: Hartmann
authors.forename: H G
authors.initials: HG
authors.lastname: Olbrich
authors.forename: R
authors.initials: R
authors.lastname: Hopf
authors.forename: M
authors.initials: M
authors.lastname: Schneider
authors.forename: B
authors.initials: B
authors.lastname: Lösse
authors.forename: M
authors.initials: M
authors.lastname: Kaltenbach
mesh_terms: D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000175:diagnosis / Q000503:physiopathology; D002303:Cardiac Output, Low / Q000175:diagnosis / Q000503:physiopathology; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis / Q000503:physiopathology*; D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis / Q000503:physiopathology*; D004562:Electrocardiography; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016277:Ventricular Function, Left / Q000502:physiology
vernacular_title: Dilatative Verlaufsform bei hypertrophischer Kardiomyopathie.