title: Non-specific X linked mental retardation.
abstract: Non-specific X linked mental retardation (MRX) is mental retardation in persons of normal physical appearance who have no recognisable features apart from a characteristic pedigree. Review of published reports shows that there is clinical variability in the degree of mental retardation within families and genetic heterogeneity, based on gene localisation, between families. We propose a classification based on genetic localisation and a set of minimal clinical features that should be recorded in the hope of identifying possible specific phenotypes.
authors.affiliation: Department of Medical Genetics, Prince of Wales Children's Hospital, Randwick, NSW, Australia.
authors.forename: B
authors.initials: B
authors.lastname: Kerr
authors.forename: G
authors.initials: G
authors.lastname: Turner
authors.forename: J
authors.initials: J
authors.lastname: Mulley
authors.forename: A
authors.initials: A
authors.lastname: Gedeon
authors.forename: M
authors.initials: M
authors.lastname: Partington
mesh_terms: D008040:Genetic Linkage; D006801:Humans; D008607:Intellectual Disability / Q000145:classification / Q000235:genetics*; D014960:X Chromosome