[Treatment of acute otitis media: comparative study of efficacy of cefatrizine and amoxicillin-clavulanic acid].
Fourty hospitalized patients (15 children, 25 adults) suffering from acute otitis media have been treated with either cefatrizine or amoxycillin-clavulanic acid. Bacteriological samples were done during surgery by tympanocentesis (N = 33) or by sampling of middle ear fluid specimens (13). H. influenzae was the most common isolate, following by Enterobacteriaceae, S. aureus, P. aeruginosa, and S. pneumoniae. We conclude that these two antibiotics can be used for treatment of acute otitis media in our country even in adults where the order of frequency of bacteria is different from those reported in children.
Chomarat
M
M
Laboratoire de Bactériologie, Centre Hospitalier Lyon-Sud, Pierre-Bénite.
Dubreuil
C
C
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000658:Amoxicillin / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002436:Cefatrizine / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D019818:Clavulanic Acid; D002969:Clavulanic Acids / Q000627:therapeutic use*; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010033:Otitis Media / Q000188:drug therapy* / Q000382:microbiology
D000900:Anti-Bacterial Agents; D002969:Clavulanic Acids; D019818:Clavulanic Acid; D000658:Amoxicillin; D002436:Cefatrizine
Traitement des otites moyennes aiguës: étude comparative de l'efficacité de la céfatrizine et de l'amoxicilline-acide clavulanique.