[Central, pulmonary and hepatic hemodynamics at the developmental stages of cardiopulmonary insufficiency].
The analysis of correlations between the time and speed parameters found out that in healthy subjects and patients with chronic nonspecific bronchitis (CNB) the blood flow in great hepatic vessels is provided by the amount of blood entering the aorta in the systole. When central hemodynamics is affected in the CNB exacerbation, this factor becomes essential also for the arterial inflow into middle-size and small branches of the hepatic artery. Persistent bronchial obstruction and labile pulmonary hypertension rise as a result of failure of adequate relations between systemic, pulmonary and hepatic hemodynamics. The condition of great arterial vessels of the liver gets dependent on lesser and greater circulation. The response of the middle-size and small branches of the hepatic artery in chronic obstructive bronchitis (functional class II) is independent of the vascular tone of the lesser and greater circulation. The conclusion is made that intrahepatic blood flow in patients with secondary pulmonary hypertension is regulated by vasoactive factors acting at the level of the organ (mainly kallikrein-kinin system and prostaglandins).
Tatarkina
N D
ND
Avdeeva
E V
EV
Orlovskaia
T G
TG
Kamennyĭ
M V
MV
D000293:Adolescent; D000328:Adult; D000368:Aged; D001991:Bronchitis / Q000150:complications / Q000503:physiopathology*; D002908:Chronic Disease; D005260:Female; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008102:Liver Circulation / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011652:Pulmonary Circulation / Q000502:physiology*; D011660:Pulmonary Heart Disease / Q000209:etiology / Q000503:physiopathology*
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