title: Duration of appearance of Vi antigen and Salmonella typhi in blood and urine of infected models.
abstract: Salmonella typhi (S typhi) infected models were established to evaluate the latex agglutination test (LAT) and staphylococcal coagglutination test (SCT) for the detection of S typhi Vi antigen in blood and urine. Antigens in serum or urine were detected within 7 days after infection with positive cultures, and decreased in 2 weeks. LAT and SCT were positive in 7 mice with no bacteria isolation from blood and urine but their spleen aspirates yielded S typhi. Both tests are rapid and sensitive and may be used for the diagnosis of typhoid infection, especially in partially treated patients when their blood cultures are negative.
authors.affiliation: Children's Hospital, Shanghai Medical University.
authors.forename: D M
authors.initials: DM
authors.lastname: Wang
authors.forename: X H
authors.initials: XH
authors.lastname: Gu
mesh_terms: D000372:Agglutination Tests / Q000379:methods; D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis* / Q000097:blood / Q000652:urine; D007841:Latex Fixation Tests; D051379:Mice; D011135:Polysaccharides, Bacterial; D012485:Salmonella typhi / Q000276:immunology*; D013205:Staphylococcal Protein A; D014435:Typhoid Fever / Q000276:immunology*
chemical_list: D000942:Antigens, Bacterial; D011135:Polysaccharides, Bacterial; D013205:Staphylococcal Protein A