title: Noncompartmental analysis in metabolism.
abstract: A new type of model called a department is formulated to complement the compartment. While a compartment may be dominated by convective transport, a department is dominated by diffusive transport. Although exit from a compartment is limited by the rate of biophysical or biochemical removal ("kc"), exit from a department is limited by the rate of transport to the site of biophysical or biochemical removal.
authors.affiliation: Institute of Biomedical Engineering, University of Toronto, Ontario, Canada.
authors.forename: K H
authors.initials: KH
authors.lastname: Norwich
mesh_terms: D000818:Animals; D001692:Biological Transport; D001842:Bone and Bones / Q000378:metabolism; D004058:Diffusion; D007700:Kinetics; D008433:Mathematics; D008660:Metabolism; D008954:Models, Biological; D011868:Radioisotopes / Q000378:metabolism
chemical_list: D011868:Radioisotopes