title: A randomised, double-blind, placebo-controlled trial of gemeprost (Cervagem) pessaries for cervical dilatation in non-pregnant women.
abstract: In a randomised, double-blind trial, 75 women received either placebo or a 1-mg gemeprost (Cervagem) pessary for cervical dilatation prior to gynecological procedures which require mechanical dilatation of the cervix. No significant difference was seen between gemeprost and placebo with respect to preoperative cervical dilatation. The incidence of vaginal bleeding and adverse effects was similar in each group.
authors.affiliation: Department of Obstetrics and Gynaecology, Hammersmith Hospital, London.
authors.forename: M G
authors.initials: MG
authors.lastname: Elder
authors.forename: G
authors.initials: G
authors.lastname: Lewis
mesh_terms: D000527:Alprostadil / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002584:Cervix Uteri / Q000187:drug effects*; D004106:Dilatation / Q000379:methods; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D010570:Pessaries; D011300:Preoperative Care; D011459:Prostaglandins E, Synthetic / Q000627:therapeutic use*
chemical_list: D011459:Prostaglandins E, Synthetic; C021182:gemeprost; D000527:Alprostadil