title: The determination of the contrast necessary for the detection of small positive or negative contrasting areas in flood field images by employing ROCs.
abstract: Flood field images are acquired and inspected visually during weekly quality control procedures for scintillation cameras. Nonuniformities are quantified by parameters such as integral and differential uniformity (IU and DU). This study is a first step toward understanding the relation between the standard quantitative parameters measured in regular quality control procedures and the performance of clinicians in the interpretation of studies conducted with the same scintillation camera. This study quantified the performance of observers to detect nonuniformities in an ideal case. Flood field images (64 x 64) were simulated on a computer. One contrasting area (2 x 2) was superimposed at random positions on each image. Positive and negative contrast values of 10%, 8%, 6%, 4%, 2%, and 0% were employed. The linearly scaled computer images were transferred to film. These films were evaluated by 11 observers to obtain receiver operating characteristic (ROC) curves. The areas (A) below the average ROCs for every contrast value were utilized as an indication of the detectability of the contrasting areas superimposed on the flood images. The results indicate areas with positive contrasts greater than 6% and negative contrasts less than -8% were detected with 95% probability (A greater than or equal to 0.95). These contrasts correspond to optical density differences of greater than 0.051 and less than -0.072, respectively (assuming a gamma, G, or gradient of 2.0 for the x-ray film characteristic curve). The contrast values and optical density differences obtained may serve as guide values, beyond which action must be taken to correct the scintillation camera nonuniformity to ensure optimum imaging. These results can be utilized by other institutions to predict the threshold contrasts of their imaging systems if G can be measured or estimated for the systems.
authors.affiliation: Department of Biophysics, Faculty of Medicine, University of the Orange Free State, Bloemfontein, South Africa.
authors.forename: E M
authors.initials: EM
authors.lastname: Geldenhuys
mesh_terms: D015902:Gamma Cameras / Q000592:standards*; D011786:Quality Control; D012372:ROC Curve