title: Paroxysmal nocturnal hemoglobinuria. Case report of MR imaging and CT findings.
abstract: A case of paroxysmal nocturnal hemoglobinuria (PNH) is presented in which MR imaging and CT findings were characteristic. The signal intensity of renal cortex was lower than that of medulla on both T1- and T2-weighted imaging. On CT without contrast enhancement the attenuation of renal cortex was higher than that of renal medulla. These findings at MR imaging and CT were the results of a deposition of hemosiderin in the cells of proximal convoluted tubules, and were helpful for diagnosis of PNH.
authors.affiliation: Department of Diagnostic Radiology, Seoul National University College of Medicine, Republic of Korea.
authors.forename: S H
authors.initials: SH
authors.lastname: Kim
authors.forename: M C
authors.initials: MC
authors.lastname: Han
authors.forename: J S
authors.initials: JS
authors.lastname: Lee
authors.forename: S
authors.initials: S
authors.lastname: Kim
mesh_terms: D005260:Female; D006457:Hemoglobinuria, Paroxysmal / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D014057:Tomography, X-Ray Computed