[The dependence of the functional activity of "immune" macrophages on T-cells].
The dependence of the functional activity of the peritoneal macrophages of mice immunized with Francisella tularensis vaccine strain on the presence of T-cells in the culture has been studied. The elimination of "immune" macrophages and sensitized T-lymphocytes by means of anti-Thy-1-2-serum has been shown to lead to a sharp decrease in both ingestive and digestive functions of the phagocytic mononuclears of peritoneal exudate to the level of the activity of macrophages isolated from intact animals.
Galaktionov
V G
VG
Skatov
D V
DV
Vasilenko
R N
RN
D000818:Animals; D000961:Antilymphocyte Serum / Q000494:pharmacology; D001202:Ascitic Fluid / Q000166:cytology / Q000276:immunology; D001428:Bacterial Vaccines / Q000276:immunology; D002478:Cells, Cultured / Q000187:drug effects / Q000276:immunology; D005604:Francisella tularensis / Q000276:immunology; D007114:Immunization; D007518:Isoantibodies / Q000494:pharmacology; D008264:Macrophages / Q000187:drug effects / Q000276:immunology*; D051379:Mice; D008808:Mice, Inbred CBA; D010587:Phagocytosis / Q000187:drug effects / Q000276:immunology; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D013997:Time Factors
D000961:Antilymphocyte Serum; D001428:Bacterial Vaccines; D007518:Isoantibodies; C035678:anti-Thy antibody
Zavisimost' funktsional'noĭ aktivnosti "immunnykh" makrofagov ot T-kletok.