title: [Determination of immunity (?)/immune response (using serological techniques].
abstract: The effective use of serological tests for the diagnosis of disease and/or infection depends both on the nature of the diagnostic problem and on the diagnostic value of positive and negative results of the test. In veterinary practice, diagnostic uses consist in (1) diagnosis in patients showing typical symptoms, (2) staging of the infection, (3) screening studies, and in patients showing typical symptoms, (2) staging of the infection, (3) screening studies, and (4) monitoring of effects of therapy. In quantitative tests for diagnostic purposes, the positive or negative value of the test may be established using either reference ranges in controls or longitudinal studies in single patients. When serological tests are performed for measuring immunity or susceptibility of animals to infection, the test(s) should be performed in conjunction with experimental challenge infection studies. This form of combined testing thus provides the levels of serum antibodies protective against disease.
authors.affiliation: Vakgroep Infectieziekten en Immunologie, Utrecht.
authors.forename: W E
authors.initials: WE
authors.lastname: Bernadina
mesh_terms: D000818:Animals; D004198:Disease Susceptibility / Q000276:immunology / Q000662:veterinary; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005188:False Negative Reactions; D005189:False Positive Reactions; D006385:Hemagglutination Inhibition Tests / Q000662:veterinary; D007159:Immunologic Tests / Q000662:veterinary*; D007239:Infections / Q000276:immunology / Q000662:veterinary*; D009500:Neutralization Tests / Q000662:veterinary; D012680:Sensitivity and Specificity
vernacular_title: Aantonen van immuniteit (?)/immuunrespons (door middel van serologische technieken).