[Severe chloroquine poisoning. Favourable outcome with diazepam therapy. A toxicokinetic study].
A severe chloroquine poisoning, featuring indicators of bad prognosis, has been treated by a diazepam-type therapy. The outcome was favourable in a dramatic way. A toxicokinetic study showed very high chloroquine plasmatic levels, consistent with the severity of the poisoning.
Furet
Y
Y
Service de pharmacologie et de toxicologie, Centre hospitalier régional et universitaire, Tours.
Jonville
A P
AP
Perrotin
D
D
Nsabiyumva
F
F
Autret
E
E
Breteau
M
M
D000293:Adolescent; D002738:Chloroquine / Q000097:blood / Q000493:pharmacokinetics / Q000506:poisoning*; D003975:Diazepam / Q000627:therapeutic use*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D011041:Poisoning / Q000188:drug therapy
D002738:Chloroquine; D003975:Diazepam
Intoxication sévère à la chloroquine. Evolution favorable sous diazépam. Etude toxicocinétique.