title: [Status of protective properties of the gastroduodenal mucosa after surgical treatment of duodenal ulcer].
abstract: The defense properties of the gastroduodenal mucosa (lymphoid system cells secreting immunoglobulins A, M, and G, as well as the secretory component IgA) were studied in 85 patients with duodenal ulcer. The acid-producing function of the stomach was tested at the same time according to the pH value and the basal and maximal acid production. Various types of vagotomy were conducted in 52 patients and resection of the stomach in the remaining patients. The results were followed-up before and after the operation. Peptic ulcer was characterized by secondary immunodeficiency. Selective proximal vagotomy restored the tissue immune defense of the mucosa, gastric resection preserved and even increased immunodeficiency.
authors.forename: V L
authors.initials: VL
authors.lastname: Manevich
authors.forename: A V
authors.initials: AV
authors.lastname: Novikova
authors.forename: A V
authors.initials: AV
authors.lastname: Upyrev
authors.forename: K A
authors.initials: KA
authors.lastname: Abikulov
mesh_terms: D000921:Antibody-Producing Cells / Q000276:immunology*; D004381:Duodenal Ulcer / Q000276:immunology* / Q000473:pathology / Q000601:surgery; D004386:Duodenum / Q000276:immunology* / Q000473:pathology; D005743:Gastrectomy; D005753:Gastric Mucosa / Q000276:immunology* / Q000473:pathology; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis / Q000096:biosynthesis*; D007413:Intestinal Mucosa / Q000276:immunology* / Q000473:pathology; D014629:Vagotomy, Proximal Gastric
chemical_list: D007136:Immunoglobulins
vernacular_title: Sostoianie zashchitnykh svoĭstv slizistoĭ gastroduodenal'noĭ zony pri khirurgicheskom lechenii iazvennoĭ bolezni dvenadtsati- perstnoĭ kishki.