[An autopsy case of primary lung leiomyosarcoma].
We report autopsy findings for a case of leiomyosarcoma originating in the right lung in an 86-year-old man. We surveyed current literatures and compared the immunohistochemical results in the present case with those reported previously in Japan. The solid tumor measured 6 x 7 x 7 cm sized and was located in the right lung. Its cut-surface appeared grayish to yellowish and contained areas of hemorrhage and necrosis. The lungs contained scattered nodular lesions less than 2 cm in diameter. Metastatic lesions were also confirmed in other tissues such as the heart, pericardium, liver, spleen, left adrenal gland and thyroid. Microscopically, 14 mitoses were detected in every 10 high-power fields. An immunohistochemical study revealed positivity for smooth muscle myosin and actin, and negativity for CEA, and appeared to be important in differential diagnosis and determination of histogenetic type.
Shimota
H
H
Department of Clinical Laboratory, Juntendo Urayasu Hospital, Juntendo University School of Medicine.
Satoh
T
T
Ishi
K
K
Iwase
A
A
D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology*; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male