title: Triglycerides, a major coronary risk factor in elderly men. A study of men born in 1913.
abstract: We examined two 'cohorts' of elderly men, 60 and 67 years old. The two 'cohorts' overlapped to a large extent in terms of numbers but not in the follow-up periods. The mean have been followed-up for 7 and 8 years respectively. Among the 748 60-year-old men without prior myocardial infarction the 7-year incidence of coronary heart disease was 8%. The incidence was related to blood pressure, smoking habits and serum triglycerides (but not serum cholesterol) both in univariate and multivariate analyses. The incidence of coronary heart disease increased 5-fold from the lowest to the highest quintile of triglycerides. Among the 595 67-year-old men without prior myocardial infarction the 8-year incidence of coronary heart disease was 11%. Both serum cholesterol and triglycerides were significant risk factors in univariate analyses but only triglycerides in multivariate analyses. The incidence of coronary heart disease increased almost three-fold from the lowest to the highest quintile of triglycerides. Increased serum triglycerides is a major coronary risk factor in elderly men.
authors.affiliation: Department of Medicine, Ostra Hospital, Sweden.
authors.forename: L
authors.initials: L
authors.lastname: Welin
authors.forename: H
authors.initials: H
authors.lastname: Eriksson
authors.forename: B
authors.initials: B
authors.lastname: Larsson
authors.forename: L O
authors.initials: LO
authors.lastname: Ohlson
authors.forename: K
authors.initials: K
authors.lastname: Svärdsudd
authors.forename: G
authors.initials: G
authors.lastname: Tibblin
authors.forename: L
authors.initials: L
authors.lastname: Wilhelmsen
mesh_terms: D000368:Aged; D015331:Cohort Studies; D003327:Coronary Disease / Q000097:blood* / Q000401:mortality; D005500:Follow-Up Studies; D006801:Humans; D015228:Hypertriglyceridemia / Q000097:blood* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000401:mortality; D011446:Prospective Studies; D012307:Risk Factors; D013548:Sweden; D014280:Triglycerides / Q000097:blood*
chemical_list: D014280:Triglycerides