[The immunochemistry of the antigenic fractions of Clostridium tetani toxin].
The localization of tetanospasmin and tetanolysin in C. tetani cells has been determined by the cytochemical method in the dynamics of the development of the microbial population. As shown in this investigation, tetanolysin, similarly to exotoxins, is released from microbial cells into the culture fluid mainly during the first 24 hours of cultivation, while tetanospasmin, similarly to endotoxins, is released only in the process of the destruction of these cells at the phase of the death of the microbial population.
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D000818:Animals; D000907:Antibodies, Bacterial / Q000276:immunology / Q000302:isolation & purification; D000942:Antigens, Bacterial / Q000276:immunology*; D000954:Antigens, Surface / Q000276:immunology; D002846:Chromatography, Affinity; D003017:Clostridium tetani / Q000276:immunology / Q000648:ultrastructure; D003593:Cytoplasm / Q000276:immunology / Q000648:ultrastructure; D007114:Immunization; D007120:Immunochemistry; D008666:Metalloendopeptidases; D011817:Rabbits; D013744:Tetanus Toxin / Q000276:immunology*
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D000954:Antigens, Surface; D013744:Tetanus Toxin; C035979:tetanospasmin; C026167:tetanolysin; D008666:Metalloendopeptidases
Immunokhimiia antigennykh fraktsiĭ stolbniachnogo toksina Clostridium tetani.