[Priapism secondary to phenothiazines].
We report two cases of priapism in patients previously treated with neuroleptic agents. None of these patients had a previous history of urological or hematological disorders. These two patients warranted emergency treatment by punction-aspiration of the corpora cavernosa and posterior cavernospongiosa shunt. The foregoing approach achieved penile detumescence in both cases. Excellent results were achieved relative to erectile function in one patient. Although the mechanism responsible for phenothiazine-induce priapism has as yet not been elucidated, it has been suggested that this might be due to adrenergic block which directly inhibits the sympathetic impulse of detumescence.
Gómez Vegas
A
A
Servicio de Urología, Hospital Universitario de San Carlos, Madrid, España.
Silmi Moyano
A
A
Blázquez Izquierdo
J
J
Corral Rosillo
J
J
Delgado Martín
J A
JA
Gómez Ruiz
J J
JJ
Prieto Chaparro
L
L
Salinas Casado
J
J
D000328:Adult; D003692:Delayed-Action Preparations / Q000009:adverse effects*; D004322:Drainage; D005476:Fluphenazine / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011317:Priapism / Q000139:chemically induced* / Q000601:surgery; D012008:Recurrence; D013881:Thioridazine / Q000009:adverse effects*
D003692:Delayed-Action Preparations; C011825:fluphenazine depot; D013881:Thioridazine; D005476:Fluphenazine
Priapismo secundario a fenotiazinas.