title: Plasma uric acid in patients receiving anticonvulsant monotherapy.
abstract: In newly diagnosed adult patients with epilepsy followed prospectively on monotherapy, carbamazepine and phenytoin were associated with a fall in plasma uric acid, but sodium valproate and phenobarbitone were associated with a rise in plasma uric acid. The mechanisms and significance of these findings are discussed.
authors.affiliation: Department of Neurology, King's College Hospital, London, U.K.
authors.forename: H A
authors.initials: HA
authors.lastname: Ring
authors.forename: A J
authors.initials: AJ
authors.lastname: Heller
authors.forename: W J
authors.initials: WJ
authors.lastname: Marshall
authors.forename: A L
authors.initials: AL
authors.lastname: Johnson
authors.forename: E H
authors.initials: EH
authors.lastname: Reynolds
mesh_terms: D000293:Adolescent; D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use*; D002220:Carbamazepine / Q000627:therapeutic use; D004827:Epilepsy / Q000097:blood* / Q000188:drug therapy; D006801:Humans; D010634:Phenobarbital / Q000627:therapeutic use; D010672:Phenytoin / Q000627:therapeutic use; D011446:Prospective Studies; D014527:Uric Acid / Q000097:blood*; D014635:Valproic Acid / Q000627:therapeutic use
chemical_list: D000927:Anticonvulsants; D014527:Uric Acid; D002220:Carbamazepine; D014635:Valproic Acid; D010672:Phenytoin; D010634:Phenobarbital