title: On the relationships between the genetic code coevolution hypothesis and the physicochemical hypothesis.
abstract: This paper analyzes the relationships between the genetic code coevolution hypothesis and the physicochemical hypothesis by means of a comparative study of the precursor-product amino acid pairs on which the former hypothesis is based. Even if the coevolution between the biosynthetic relationships of amino acids and the organization of the genetic code is not questioned in this paper, the results and the arguments used lead us to believe that the selective pressures considered essential by the physicochemical postulates, played a more active role than that of the precursor-product relationships in defining the allocation of these amino acids in the genetic code. It is furthermore pointed out that the two evolutionary hypothesis might be aspects of the same selective pressure, and thus difficult to differentiate.
authors.affiliation: International Institute of Genetics and Biophysics, CNR Via G. Marconi 10, Napoli, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Di Giulio
mesh_terms: D000596:Amino Acids; D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D003062:Codon / Q000235:genetics*; D005815:Genetic Code; D008957:Models, Genetic; D000069497:Origin of Life; D011336:Probability
chemical_list: D000596:Amino Acids; D003062:Codon