Glaucoma and Peters' anomaly. A clinicopathologic case report.
A 26-year-old black woman with Peters' anomaly who had been followed since early childhood developed an open-angle form of glaucoma, which required filtering surgery. Light and electron microscope studies of the trabeculectomy specimen, which was obtained by en bloc resection of the trabecular meshwork and iridectomy specimen, revealed that the structures of the anterior-chamber angle were grossly normal aside from evidence of premature aging on the basis of abundant broad-banded collagen fibers in the trabecular lamellae.
Heath
D H
DH
Duke University Medical Center, Duke University Eye Center, Durham, NC 27710.
Shields
M B
MB
D000328:Adult; D000867:Anterior Chamber / Q000002:abnormalities* / Q000473:pathology; D003094:Collagen / Q000648:ultrastructure; D003315:Cornea / Q000002:abnormalities* / Q000473:pathology; D005260:Female; D005902:Glaucoma, Open-Angle / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D010862:Pilocarpine / Q000627:therapeutic use; D013577:Syndrome; D014129:Trabecular Meshwork / Q000473:pathology; D014130:Trabeculectomy
D010862:Pilocarpine; D003094:Collagen