title: Low prevalence of delta hepatitis virus infection among blacks in Natal.
abstract: The prevalence of delta hepatitis virus (DHV) infection among hepatitis B surface antigen (HBsAg)-positive black subjects in Natal was determined. A total of 172 subjects was tested for the presence of antibodies to DHV; all were HBsAg-positive. They comprised three groups: 51 urban children identified in a community-based seroprevalence survey, 81 subjects identified during a family study, and 40 institutionalised children. None of the 172 subjects was positive for antibodies to DHV. Based on calculations using a binomial distribution of infection, there was a 95% probability that the prevalence of DHV infection was below 30/100,000 HBsAg-positive persons. While DHV infection was found to be rare among blacks in Natal, the risk of delta hepatitis becoming widespread is ever-present, since the high incidence of hepatitis B virus infection in black children provides ample opportunity for the concomitant spread of DHV.
authors.affiliation: Research Institute for Diseases in a Tropical Environment, South African Medical Research Council, Durban.
authors.forename: S S
authors.initials: SS
authors.lastname: Abdool Karim
authors.forename: I M
authors.initials: IM
authors.lastname: Windsor
authors.forename: W
authors.initials: W
authors.lastname: Gopaul
mesh_terms: D001741:Black or African American; D044383:Black People; D002648:Child; D002675:Child, Preschool; D003699:Hepatitis D / Q000453:epidemiology*; D006801:Humans; D013019:South Africa / Q000453:epidemiology