title: Dysphagia in Bouviers associated with muscular dystrophy; evaluation of 24 cases.
abstract: Twenty-four Bouviers with dysphagia were examined between October 1986 and October 1988. The type of dysphagia was characterised by the results from the clinical examination, the videofluorographic examination and the electromyographic recordings from the oral, pharyngeal, and esophageal muscles. Electromyography indicated neurogenic as well as myogenic causes of dysphagia. Tissues from 10 dogs were available for histopathologic examination. In nine dogs there was a progressive muscular degeneration of the pharyngeal and/or esophageal muscles, resembling muscular dystrophy. In two of these dogs the same abnormalities were also noticed in the masseter and temporalis muscles and in the intrinsic laryngeal muscles. In one dog small areas with hyalin degeneration and fragmentation of muscle fibres were found in the cricopharyngeal muscle. No abnormalities in nerve tissue were found. Muscular dystrophy is a hereditary disease. The mode of transmission in these Bouviers is not yet known.
authors.affiliation: Department of Clinical Sciences of Companion Animals, University of Utrecht, The Netherlands.
authors.forename: M E
authors.initials: ME
authors.lastname: Peeters
authors.forename: A J
authors.initials: AJ
authors.lastname: Venker-van Haagen
authors.forename: S A
authors.initials: SA
authors.lastname: Goedegebuure
authors.forename: W T
authors.initials: WT
authors.lastname: Wolvekamp
mesh_terms: D000818:Animals; D001947:Breeding; D003402:Creatine Kinase / Q000097:blood; D003680:Deglutition Disorders / Q000209:etiology / Q000628:therapy / Q000662:veterinary*; D004283:Dog Diseases / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D004285:Dogs; D004576:Electromyography / Q000662:veterinary; D005260:Female; D008297:Male; D009137:Muscular Dystrophy, Animal / Q000150:complications* / Q000235:genetics / Q000473:pathology
chemical_list: D003402:Creatine Kinase