title: [Severe chloroquine poisoning. Favourable outcome with diazepam therapy. A toxicokinetic study].
abstract: A severe chloroquine poisoning, featuring indicators of bad prognosis, has been treated by a diazepam-type therapy. The outcome was favourable in a dramatic way. A toxicokinetic study showed very high chloroquine plasmatic levels, consistent with the severity of the poisoning.
authors.affiliation: Service de pharmacologie et de toxicologie, Centre hospitalier régional et universitaire, Tours.
authors.forename: Y
authors.initials: Y
authors.lastname: Furet
authors.forename: A P
authors.initials: AP
authors.lastname: Jonville
authors.forename: D
authors.initials: D
authors.lastname: Perrotin
authors.forename: F
authors.initials: F
authors.lastname: Nsabiyumva
authors.forename: E
authors.initials: E
authors.lastname: Autret
authors.forename: M
authors.initials: M
authors.lastname: Breteau
mesh_terms: D000293:Adolescent; D002738:Chloroquine / Q000097:blood / Q000493:pharmacokinetics / Q000506:poisoning*; D003975:Diazepam / Q000627:therapeutic use*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D011041:Poisoning / Q000188:drug therapy
chemical_list: D002738:Chloroquine; D003975:Diazepam
vernacular_title: Intoxication sévère à la chloroquine. Evolution favorable sous diazépam. Etude toxicocinétique.