Hypo-osmotic sperm swelling test does not assess fertilizing capacity of human spermatozoa.
The hypo-osmotic sperm swelling (HOSS) test was performed on semen samples of five normospermic men from couples with prolonged infertility. Previously, the men had negative results of the zona-free hamster oocyte (ZFHO) test on two different ejaculates and the wives subsequently had become pregnant by donor insemination. A high swelling percentage (at least 60%) was found in all five men. It would appear that the HOSS test does not assess fertilizing capacity.
Jager
S
S
Department of Obstetrics and Gynaecology, University Hospital, Groningen, The Netherlands.
Kremer
J
J
Wijchman
J
J
D000818:Animals; D006224:Cricetinae; D005260:Female; D005298:Fertility / Q000502:physiology*; D006801:Humans; D066298:In Vitro Techniques; D007248:Infertility, Male / Q000503:physiopathology*; D008297:Male; D009994:Osmolar Concentration; D013084:Sperm-Ovum Interactions; D013094:Spermatozoa / Q000502:physiology*