title: Assembly of cytoplasmic and smooth muscle myosins.
abstract: Filaments formed from a variety of smooth and non-muscle myosins are dynamic polymers whose phosphorylation-dependent assembly and disassembly can be coupled to changes in enzymatic activity. Phosphorylation-insensitive assembly, which allows independent control of activity and polymerization, is an alternative mechanism used by Acanthamoeba myosin. Domains of the tail responsible for assembly and regulation have now been identified for a number of myosins.
authors.affiliation: Rosenstiel Research Center, Brandeis University, Waltham, Massachusetts 02254.
authors.forename: K M
authors.initials: KM
authors.lastname: Trybus
mesh_terms: D000048:Acanthamoeba; D000818:Animals; D003593:Cytoplasm / Q000378:metabolism*; D004023:Dictyostelium; D009119:Muscle Contraction / Q000502:physiology; D009130:Muscle, Smooth / Q000378:metabolism* / Q000502:physiology; D009218:Myosins / Q000378:metabolism*; D010766:Phosphorylation
chemical_list: D009218:Myosins