Light-sense, flicker and resolution perimetry in glaucoma: a comparative study.
A total of 106 eyes of 106 patients with different types of glaucoma were examined by automated light-sense, flicker and resolution perimetry (Humphrey Field Analyzer, program 30-2; flicker perimeter as described by Lachenmayr [16, 18]; resolution perimeter as devised by Frisén [4, 6, 8-11]). The fields were classified in a masked fashion as being normal or as having purely diffuse loss, purely localized loss or diffuse as well as localized loss. As compared with light-sense perimetry, resolution perimetry had a markedly lower sensitivity in the detection of glaucomatous damage (77%) but a high specificity (93%); the comparison of resolution perimetry with flicker perimetry showed similar results (sensitivity, 75%; specificity, 85%). When flicker perimetry was compared with light-sense perimetry and vice versa, the sensitivity was high (95% and 94%, respectively), but the specificity was low (57% and 62%, respectively). The prevalence of detection of diffuse loss by both light-sense and resolution perimetry was related to visual acuity, whereas flicker perimetry did not show such a relationship.
Lachenmayr
B J
BJ
Department of Ophthalmology, University of British Columbia, Vancouver, Canada.
Drance
S M
SM
Douglas
G R
GR
Mikelberg
F S
FS
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005425:Flicker Fusion; D005901:Glaucoma / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure; D008027:Light; D008875:Middle Aged; D009898:Optic Disk / Q000503:physiopathology; D012680:Sensitivity and Specificity; D014792:Visual Acuity; D058609:Visual Field Tests / Q000379:methods*; D014794:Visual Fields