Case report: mammographic and sonographic demonstration of extramedullary haematopoiesis of the breast.
A female patient with agnogenic myeloid metaplasia presented with hepatosplenomegaly and a palpable mass in the right breast. Mammography showed an asymmetric pattern of confluent densities and sonography revealed several smooth, homogeneous and echo-poor masses of variable sizes in both breasts. Excision biopsy of the mass in the right breast revealed extramedullary haematopoiesis as did histopathologic examination of the liver and the spleen. The data are discussed with emphasis on the complementary character of both diagnostic modalities and the resemblance to lymphoma of the breast, although the findings are too non-specific to rule out breast carcinoma. Knowledge of the clinical history and histopathology are necessary to make the proper diagnosis.
Zonderland
H M
HM
Department of Radiology, University Hospital Dijkzigt, Erasmus University, Rotterdam, The Netherlands.
Michiels
J J
JJ
ten Kate
F J
FJ
D001940:Breast / Q000473:pathology*; D005260:Female; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology; D008327:Mammography; D008875:Middle Aged; D055728:Primary Myelofibrosis / Q000473:pathology; D013154:Spleen / Q000000981:diagnostic imaging / Q000473:pathology; D016217:Ultrasonography, Mammary