[The thioldisulfide system as one of the elements of compensatory mechanisms in influenza].
The paper presents the results of a comparative study of changes in a thioldisulfide component of the antioxidation system in cases of sublethal and lethal patterns of influenza. The both patterns were featured with a correlation between individual values of thioldisulfide equilibrium and the severity of virus-induced pathological process. Characteristic features of SH/SS coefficient in the lethal pattern of the infection were evidently linked with a specific adaptation of the body under the effect of strong irritants. The possibility to use the parameters of the thioldisulfide system performance for the prognosis of the influenza course was discussed.
Leont'eva
G F
GF
Goncharova
L L
LL
Dubrovina
T Ia
TIa
D000818:Animals; D000921:Antibody-Producing Cells / Q000378:metabolism*; D004195:Disease Models, Animal; D008168:Lung / Q000378:metabolism* / Q000473:pathology; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009976:Orthomyxoviridae Infections / Q000276:immunology / Q000378:metabolism* / Q000473:pathology; D012720:Severity of Illness Index; D013438:Sulfhydryl Compounds / Q000378:metabolism*; D013440:Sulfides / Q000378:metabolism*
D013438:Sulfhydryl Compounds; D013440:Sulfides
Tioldisul'fidnaia sistema kak odin iz élementov kompensatornykh mekhanizmov pri grippe.