title: [Clinical studies on cefpirome in pediatrics].
abstract: Cefpirome (CPR, HR 810) was given intravenously to 10 children with acute bacterial infections including 8 with acute pneumonia, 1 each with acute pleuritis and urinary tract infections. Good to excellent clinical responses were obtained in all of the 10 patients and bacterial eradication were obtained for all 8 strains found in these cases. Slight elevation of GOT, GPT and eosinophilia were observed in 1 case each. From the above clinical results, it appears that CPR is a useful antibiotic for treatment of pediatric patients with various bacterial infections.
authors.affiliation: Department of Pediatrics, Takamatsu Red Cross Hospital.
authors.forename: T
authors.initials: T
authors.lastname: Sekiguchi
authors.forename: Y
authors.initials: Y
authors.lastname: Shiino
authors.forename: K
authors.initials: K
authors.lastname: Murakawa
authors.forename: M
authors.initials: M
authors.lastname: Nishimori
authors.forename: H
authors.initials: H
authors.lastname: Kouzan
authors.forename: K
authors.initials: K
authors.lastname: Ohara
authors.forename: T
authors.initials: T
authors.lastname: Okamoto
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001419:Bacteria / Q000187:drug effects; D002511:Cephalosporins / Q000008:administration & dosage* / Q000494:pharmacology / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004341:Drug Evaluation; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D007223:Infant; D007275:Injections, Intravenous; D008297:Male; D010998:Pleurisy / Q000188:drug therapy* / Q000382:microbiology; D011014:Pneumonia / Q000188:drug therapy* / Q000382:microbiology; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology; D000097572:Cefpirome
chemical_list: D002511:Cephalosporins; D000097572:Cefpirome