[The lithium oxybutyrate correction of disorders in higher nervous activity in the progeny of alcoholized male rats].
In experiments on rats it was shown that alcohol administered intragastrically in a dose of 8 g/kg for 4 weeks produced long-term disturbances of CNS function in the offspring similar to those observed under clinical conditions. Early postnatal administration of lithium oxybutyrate (from the 8th through the 14th day of life) was found to prevent the development of the disturbances.
Nemova
E P
EP
Liubimov
B I
BI
Smol'nikova
N M
NM
Krylova
A M
AM
Trofimov
S S
SS
D000375:Aging / Q000187:drug effects / Q000502:physiology; D000437:Alcoholism / Q000188:drug therapy* / Q000503:physiopathology; D000818:Animals; D001927:Brain Diseases / Q000139:chemically induced* / Q000188:drug therapy / Q000503:physiopathology; D004353:Drug Evaluation, Preclinical; D005220:Fathers; D006613:Higher Nervous Activity / Q000187:drug effects* / Q000502:physiology; D006885:Hydroxybutyrates / Q000627:therapeutic use*; D008094:Lithium / Q000627:therapeutic use*; D008297:Male; D009942:Organometallic Compounds / Q000627:therapeutic use*; D051381:Rats
D006885:Hydroxybutyrates; D009942:Organometallic Compounds; C022826:lithium hydroxybutyrate; D008094:Lithium
Korrektsiia litiia oksibutiratom narusheniĭ vyssheĭ nervnoĭ deiatel'nosti potomstva alkogolizirovannykh krys-samtsov.