title: Pulmonary infiltrates with eosinophilia due to naproxen.
abstract: An increasing number of drugs have been implicated in the etiology of eosinophilic pneumonia characterized by the development of pulmonary infiltrates, and peripheral blood eosinophilia. Naproxen is a commonly used nonsteroidal anti-inflammatory drug which may be added to the growing list of pharmacologic agents associated with infiltrative pulmonary lesions. A case of eosinophilic pneumonia induced by Naproxen is described. The results of TBLB, a lymphocyte stimulation test, and a challenge test supported this diagnosis.
authors.affiliation: Department of Internal Medicine, Ishikawa Prefectural Central Hospital, Kanazawa, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Ogawa
authors.forename: K
authors.initials: K
authors.lastname: Kurashima
authors.forename: M
authors.initials: M
authors.lastname: Namura
authors.forename: H
authors.initials: H
authors.lastname: Kanaya
authors.forename: Y
authors.initials: Y
authors.lastname: Kawamura
authors.forename: T
authors.initials: T
authors.lastname: Ohka
authors.forename: H
authors.initials: H
authors.lastname: Kurumaya
authors.forename: M
authors.initials: M
authors.lastname: Yasui
authors.forename: M
authors.initials: M
authors.lastname: Fujimura
authors.forename: T
authors.initials: T
authors.lastname: Matsuda
mesh_terms: D000368:Aged; D001706:Biopsy; D004342:Drug Hypersensitivity / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008213:Lymphocyte Activation / Q000187:drug effects; D009288:Naproxen / Q000009:adverse effects* / Q000494:pharmacology / Q000627:therapeutic use; D010003:Osteoarthritis / Q000150:complications / Q000188:drug therapy; D011657:Pulmonary Eosinophilia / Q000139:chemically induced* / Q000473:pathology
chemical_list: D009288:Naproxen