title: Dye to use with virus challenge for testing barrier materials.
abstract: Can FD&C Blue no. 1 dye photoinactivate bacteriophages phi X174, T7, PRD1, and phi 6 under laboratory lighting conditions? At high levels of light, the dye (500 microM) photoinactivated only phi 6. Thus, this dye can be used at concentrations up to 500 microM with bacteriophages phi X174, T7, and PRD1 to test barrier material integrity.
authors.affiliation: Center for Devices and Radiological Health, Food and Drug Administration, Rockville, Maryland 20857.
authors.forename: C D
authors.initials: CD
authors.lastname: Lytle
authors.forename: R P
authors.initials: RP
authors.lastname: Felten
authors.forename: W
authors.initials: W
authors.lastname: Truscott
mesh_terms: D001435:Bacteriophages / Q000187:drug effects* / Q000528:radiation effects; D001557:Benzenesulfonates / Q000494:pharmacology*; D004396:Coloring Agents / Q000494:pharmacology*; D008027:Light; D011481:Protective Clothing; D013056:Spectrophotometry, Ultraviolet; D014775:Virus Activation / Q000187:drug effects / Q000528:radiation effects
chemical_list: D001557:Benzenesulfonates; D004396:Coloring Agents; C006796:brilliant blue