title: [The anesthetic management of a patient with the malignant hyperthermia trait diagnosed preoperatively].
abstract: A patient for fixation of ankle arthrodesis diagnosed as having malignant hyperthermia trait preoperatively is reported. A 17 year old man was anesthetized with enflurane for orthopedic surgery of the knee joint. At that time malignant hyperthermia developed. He was critically ill, but resuscitated and recovered from acute renal failure on 7th day after operation. Ca2+ release test was performed. Ca2+ releasing speed was prominently accelerated in this patient. We could identify him as having malignant hyperthermia trait. Epidural anesthesia with procaine chloride was given cautiously. No drug which may induce malignant hyperthermia was used. Nevertheless, malignant hyperthermia occurred. This disease has various forms of presentation. The mechanism is equivocal, and in some cases, it is difficult to judge it immediately. This patient was managed without complication. We consider that tourniquet and stress provoked signs of malignant hyperthermia in this patient.
authors.affiliation: Department of Anesthesiology, Kitasato University School of Medicine, Sagamihara.
authors.forename: K
authors.initials: K
authors.lastname: Fujiwara
authors.forename: T
authors.initials: T
authors.lastname: Takenaka
authors.forename: S
authors.initials: S
authors.lastname: Okada
authors.forename: S
authors.initials: S
authors.lastname: Nomiyama
authors.forename: S
authors.initials: S
authors.lastname: Watanabe
authors.forename: R
authors.initials: R
authors.lastname: Tanaka
mesh_terms: D000293:Adolescent; D000767:Anesthesia, Epidural; D006801:Humans; D008297:Male; D008305:Malignant Hyperthermia / Q000517:prevention & control*; D009985:Orthopedics; D011343:Procaine
chemical_list: D011343:Procaine