Severe hypomagnesemia associated with pentamidine therapy.
A case of severe hypomagnesemia in a patient with AIDS that manifested as changes in mental status is presented. The hypomagnesemia was due to renal wasting of magnesium, most probably caused by pentamidine-induced renal tubular injury. This entity has been reported once before and should be considered in the differential diagnosis of altered mental status in patients with AIDS.
Gradon
J D
JD
Divisions of Infectious Diseases, Maimonides Medical Center, Brooklyn, New York 11219.
Fricchione
L
L
Sepkowitz
D
D
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D005260:Female; D006801:Humans; D008274:Magnesium / Q000097:blood*; D008275:Magnesium Deficiency / Q000139:chemically induced*; D010419:Pentamidine / Q000009:adverse effects* / Q000627:therapeutic use; D011020:Pneumonia, Pneumocystis / Q000150:complications / Q000188:drug therapy*
D010419:Pentamidine; D008274:Magnesium