title: Ornithine decarboxylase immunoreactivity in the pituitary gland. A comparative lightmicroscopical study.
abstract: In the present study efforts are made to localize ornithine decarboxylase enzyme protein--the key enzyme of polyamine biosynthesis--in the adenohypophysis of different vertebrates by means of immunocytochemistry. The antigenic expression of ornithine decarboxylase was revealed in the pituitary of the clawed frog (Xenopus laevis D.), but not in rat and human adenohypophysis. The immunocytochemical results are compared with the staining pattern of the periodic acid-Schiff-reaction. No correlation between these results and the immunocytochemically obtained data has been found. Conclusions are drawn from the location of the enzyme and possible phylogenetic and humoral regulation mechanism.
authors.affiliation: Institute of Neurobiology and Brain Research, Magdeburg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Müller
authors.forename: H G
authors.initials: HG
authors.lastname: Bernstein
authors.forename: H
authors.initials: H
authors.lastname: Aurin
authors.forename: M
authors.initials: M
authors.lastname: Järvinen
authors.forename: A E
authors.initials: AE
authors.lastname: Pajunen
mesh_terms: D000818:Animals; D003593:Cytoplasm / Q000201:enzymology; D006801:Humans; D007124:Immunoenzyme Techniques; D009955:Ornithine Decarboxylase / Q000032:analysis*; D010902:Pituitary Gland / Q000201:enzymology*; D010903:Pituitary Gland, Anterior / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains; D014982:Xenopus laevis
chemical_list: D009955:Ornithine Decarboxylase