title: Lyotropic liquid crystals and the structural lipids of the stratum corneum.
abstract: Lipids were extracted from human stratum corneum and the remaining corneocytes were reaggregated with different lyotropic liquid crystals. Water transport through the reaggregated stratum corneum was determined using a diffusion chamber according to Smith and Blank. The permeability constant for the reaggregated stratum corneum with natural lipids was 25-40% lower than that with the surfactant liquid crystals, but there was no significant difference between different liquid crystals.
authors.affiliation: Chemistry Department, Clarkson University, Potsdam, N.Y. 13699.
authors.forename: I
authors.initials: I
authors.lastname: Kayali
authors.forename: T
authors.initials: T
authors.lastname: Suhery
authors.forename: S E
authors.initials: SE
authors.lastname: Friberg
authors.forename: F A
authors.initials: FA
authors.lastname: Simion
authors.forename: L D
authors.initials: LD
authors.lastname: Rhein
mesh_terms: D000328:Adult; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006801:Humans; D066298:In Vitro Techniques; D050356:Lipid Metabolism; D008055:Lipids / Q000737:chemistry; D010539:Permeability; D010713:Phosphatidylcholines; D012867:Skin / Q000737:chemistry* / Q000166:cytology / Q000378:metabolism; D012997:Solvents; D014867:Water / Q000502:physiology
chemical_list: D008055:Lipids; D010713:Phosphatidylcholines; D012997:Solvents; D014867:Water