[The protective action of interferon type I in experimental Salmonella infection].
The effect of interferon, type 1, on the course of Salmonella infection in mice has been studied. The study has shown that the injection of homologous interferon of type 1 leads to the rapid elimination of the infective agent from the blood and organs of infected mice. Morphological study has shown that the injection of the preparations of interferon of type 1 may diminish pathological changes in the organs of the infected animals and the coagulation system of their blood.
Fil'chakov
I V
IV
Anisimova
Iu N
IuN
Kramarev
S A
SA
Spivak
N Ia
NIa
D000818:Animals; D004353:Drug Evaluation, Preclinical; D007370:Interferon Type I / Q000627:therapeutic use*; D008099:Liver / Q000382:microbiology / Q000473:pathology; D008168:Lung / Q000473:pathology; D051379:Mice; D008815:Mice, Inbred Strains; D012481:Salmonella Infections, Animal / Q000097:blood / Q000382:microbiology / Q000473:pathology / Q000517:prevention & control*; D012486:Salmonella typhimurium; D018805:Sepsis / Q000097:blood / Q000382:microbiology; D013154:Spleen / Q000382:microbiology; D013916:Thrombelastography; D013997:Time Factors
D007370:Interferon Type I
Izuchenie protektivnogo deĭstviia interferona I tipa pri éksperimental'noĭ sal'monelleznoĭ infektsii.