title: Malignant prolactinomas.
abstract: Six cases of malignant prolactinoma have been reported; an additional two cases are presented here and the literature is reviewed. Diagnosis rests upon evidence of metastasis rather than histological criteria per se. Cases have arisen from known adenomas, particularly the invasive type. Bromocriptine is a useful palliative. The features and treatment of malignant prolactinoma are discussed.
authors.affiliation: Department of Neurosurgery, Prince Henry's Hospital, Melbourne, Australia.
authors.forename: E A
authors.initials: EA
authors.lastname: Popovic
authors.forename: J R
authors.initials: JR
authors.lastname: Vattuone
authors.forename: K H
authors.initials: KH
authors.lastname: Siu
authors.forename: I
authors.initials: I
authors.lastname: Busmanis
authors.forename: M J
authors.initials: MJ
authors.lastname: Pullar
authors.forename: J
authors.initials: J
authors.lastname: Dowling
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000473:pathology; D015175:Prolactinoma / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary