title: Surgical options in 424 patients with primary breast cancer without systemic metastases.
abstract: Mastectomy was dictated by medical considerations in about 40% of 424 consecutive patients who had invasive breast cancer with no evidence of systemic metastases. Half of the women considered suitable for local excision of the breast cancer followed by radiotherapy (conservation) elected to have mastectomy, and intraoperative findings dictated mastectomy in about 20% of those electing conservation. Consequently, conservation was accomplished in about one quarter of those treated for breast cancer. Younger rather than older women more frequently expressed the desire for breast conservation.
authors.affiliation: Department of Surgery, University of Wisconsin, Madison 53792.
authors.forename: W H
authors.initials: WH
authors.lastname: Wolberg
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols; D001943:Breast Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery*; D002985:Clinical Protocols; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008408:Mastectomy; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010358:Patient Participation