[The cytochemical marking of lymphocyte subpopulations in determining the immunoreactivity status of children vaccinated with a live measles vaccine].
In 54 children aged 1.5-2 years, immunized with the same batch of live measles vaccine prepared from strain, the relative and absolute numbers of different lymphocyte subpopulations were determined in parallel by means of two cytochemical reactions: for acid alpha-naphthyl acetate esterase and acid phosphatase in their dynamics. According to the data obtained in these reactions, the determination of lymphocyte subpopulations by two cytochemical methods in the same blood sample yielded similar results indicating that immunization with attenuated measles virus strain induced a rise in the number or zero lymphocytes and was accompanied by the decrease of the immunoregulatory index (T-helper/T-suppressor ratio), most pronounced in children with a high level of antibody formation.
Zakharova
T R
TR
Bolotovskiĭ
V M
VM
Titova
N S
NS
Ivanova
L A
LA
Shtul'berg
M Kh
MKh
D000135:Acid Phosphatase / Q000097:blood; D000937:Antigen-Antibody Reactions / Q000502:physiology*; D002675:Child, Preschool; D006651:Histocytochemistry; D006801:Humans; D007114:Immunization; D007223:Infant; D007958:Leukocyte Count; D016131:Lymphocyte Subsets / Q000201:enzymology*; D008458:Measles Vaccine / Q000276:immunology*; D009283:Naphthol AS D Esterase / Q000097:blood; D013997:Time Factors
D008458:Measles Vaccine; D009283:Naphthol AS D Esterase; D000135:Acid Phosphatase
Tsitokhimicheskaia markirovka subpopuliatsiĭ limfotsitov pri opredelenii sostoianiia immunoreaktivnosti u deteĭ, vaktsinirovannykh zhivoĭ korevoĭ vaktsinoĭ.