title: [Pathogenesis of severe vision deficiency in school-age children in Hungary].
abstract: A population-based aetiological study was carried out on 6 to 14 year-old severely visually handicapped children in Hungary. Of the 547 recorded cases 491 (90%) were included in the analysis. Eleven aetiological groups were separated: isolated cataracts (16.7%), congenital abnormalities of the eye (15.1%), high myopia +/- retinal detachment and other cases (13.4%), retinopathia praematurorum (11.0%), choroidoretinal degenerations (10.0%), syndromes (9.6%), nystagmus and/or hypermetropia (9.0%), isolated and complicated optic atrophy (6.7%), postnatal causes (4.9%), retinoblastoma (1.8%), praenatal causes (1.8%). A significantly higher rate of previous induced abortions was found in the group of retinopathia praematurorum. Perinatal damage syndrome and Mendelian monogenic defects are the two most common aetiological categories in the origin of severe visual handicaps in Hungary.
authors.affiliation: Humángenetikai és Teratológiai Osztály, Országos Közegészségügyi Intézet--WHO, Orökletes Artalmak Társadalmi Megelözése, Együttmüködési Központ, Budapest.
authors.forename: E
authors.initials: E
authors.lastname: Czeizel
authors.forename: E
authors.initials: E
authors.lastname: Törzs
authors.forename: J
authors.initials: J
authors.lastname: Kovács
authors.forename: G
authors.initials: G
authors.lastname: Szabó
authors.forename: M
authors.initials: M
authors.lastname: Vitéz
authors.forename: L
authors.initials: L
authors.lastname: Garcia Diaz
mesh_terms: D000293:Adolescent; D002648:Child; D005128:Eye Diseases / Q000150:complications* / Q000453:epidemiology / Q000235:genetics; D005260:Female; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D008297:Male; D012572:School Health Services; D014786:Vision Disorders / Q000453:epidemiology / Q000209:etiology* / Q000235:genetics
vernacular_title: Az iskoláskorú súlyos látási fogyatékos gyermekek kóreredete Magyarországon.