title: Clinical effect and mechanism of cariostatic action of fluoride-containing toothpastes: a review.
abstract: Caries reduction has been observed in certain parts of the western world. The reduction coincides with the timing of the introduction of fluoride-containing toothpastes and no other factors can explain the caries reduction. It is possible that improved oral hygiene and use of fluoride have a synergistic effect.
authors.affiliation: Department of Paedodontics, University of Oslo, Norway.
authors.forename: G
authors.initials: G
authors.lastname: Rølla
authors.forename: B
authors.initials: B
authors.lastname: Ogaard
authors.forename: R de A
authors.initials: Rde A
authors.lastname: Cruz
mesh_terms: D002327:Cariostatic Agents; D003731:Dental Caries / Q000517:prevention & control; D003743:Dental Enamel / Q000187:drug effects; D005459:Fluorides / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D014100:Toothpastes
chemical_list: D002327:Cariostatic Agents; D014100:Toothpastes; D005459:Fluorides