Teebi hypertelorism syndrome (brachycephalofrontonasal dysplasia) in a U.S. family.
Teebi (Am J Med Genet 28:581-591, 1987) described a pattern of anomalies in an Arab kindred involving 16 individuals in 4 generations. Although some findings were similar to those in craniofrontonasal dysplasia, absence of craniosynostosis, normal to slightly broad nasal tip, normal nails, and male to male transmission distinguished this as a separate entity. This paper describes a U.S. family with similar findings, involving 6 individuals (2 male and 4 female) in 4 generations, with male to male transmission.
Stratton
R F
RF
Department of Pediatrics, Wilford Hall U.S. Air Force Medical Center, Lackland AFB, Texas 78236-5300.
D002675:Child, Preschool; D003241:Consanguinity; D005260:Female; D006801:Humans; D006972:Hypertelorism / Q000235:genetics*; D008297:Male; D010375:Pedigree; D013577:Syndrome