title: Quantitative production of prostaglandin E2 and its metabolites by human fetal membranes.
abstract: Cultured amnion, choriodecidua and intact fetal membrane produced similar quantities of prostaglandin E2 (PGE2) (1-5 ng/ml). Choriodecidua and intact fetal membrane also produced very high levels of PGE2 metabolites (100-1000 ng/ml). The total production of PGE (PGE2 + PGE2 metabolites) was similar in intact fetal membrane and in choriodecidua, suggesting that the amnion, although a source of PGE2, contributes little to the overall PGE production by fetal membranes.
authors.affiliation: Institute of Obstetrics and Gynaecology, Royal Postgraduate Medical School, Hammersmith Hospital, London.
authors.forename: H
authors.initials: H
authors.lastname: Khan
authors.forename: M H
authors.initials: MH
authors.lastname: Sullivan
authors.forename: R
authors.initials: R
authors.lastname: Helmig
authors.forename: C K
authors.initials: CK
authors.lastname: Roseblade
authors.forename: N
authors.initials: N
authors.lastname: Uldbjerg
authors.forename: M G
authors.initials: MG
authors.lastname: Elder
mesh_terms: D000650:Amnion / Q000378:metabolism; D002823:Chorion / Q000378:metabolism; D046508:Culture Techniques; D015232:Dinoprostone / Q000032:analysis / Q000378:metabolism*; D005321:Extraembryonic Membranes / Q000378:metabolism*; D006801:Humans
chemical_list: D015232:Dinoprostone