[Effects of preoperative local administration of BRM on cellular immunity and prognosis of patients with esophageal cancer].
We studied the effects of OK-432 administered preoperatively on the cellular immunity and prognosis of patients with esophageal cancer. The preoperative injection of OK-432 was effective to preserve the NK activity in the peripheral blood. Especially the local priming and eliciting with OK-432 seemed to contribute to the activation of NK cells in the regional lymph nodes and to the improved prognosis of the patients.
Tanaka
Y
Y
Dept. of Pathology, Saitama Cancer Center.
Miyama
T
T
Suda
Y
Y
Fujita
K
K
Takubo
K
K
D004938:Esophageal Neoplasms / Q000276:immunology / Q000628:therapy*; D006801:Humans; D007111:Immunity, Cellular; D007271:Injections, Intradermal; D015552:Injections, Intralesional; D007694:Killer Cells, Natural / Q000276:immunology*; D010844:Picibanil / Q000008:administration & dosage*; D011300:Preoperative Care; D011379:Prognosis
D010844:Picibanil