title: [Acute posttraumatic lung failure. Its treatment through pressure-limited respiration and continuous postural change].
abstract: Nine patients (4 women and 5 men; mean age 31 [20-48] years) with severe posttraumatic adult respiratory distress syndrome (ARDS) were treated with continuous postural change (kinetic bed) and pressure-limited ventilation. Seven patients survived; only one patient died as a result of pulmonary insufficiency. As compliance was markedly reduced (less than 20 ml/cm H2O), low stroke volumes (up to 380 ml) and high respiratory rate (up to 45/min) were employed to keep airway peak pressure below 40 mmHg. Kinetic treatment lasted for a mean of 14 (2-28) days; artificial ventilation was maintained for 31 (9-49) days. Practical problems of the method are the intensive nursing care required for the kinetic bed and the risk of decubitus ulcers, as well as disconnection of infusion tubing. The results indicate that kinetic treatment with pressure-limited ventilation constitutes a low-risk and, in many cases, effective treatment of severe ARDS.
authors.affiliation: Klinik für Abdominal- und Transplantationschirurgie, Medizinische Hochschule Hannover.
authors.forename: H J
authors.initials: HJ
authors.lastname: Schlitt
authors.forename: U
authors.initials: U
authors.lastname: Werner
authors.forename: P
authors.initials: P
authors.lastname: Schandelmaier
authors.forename: C
authors.initials: C
authors.lastname: Krettek
authors.forename: K
authors.initials: K
authors.lastname: Dreinhöfer
authors.forename: J
authors.initials: J
authors.lastname: Hauss
authors.forename: R
authors.initials: R
authors.lastname: Pichlmayr
mesh_terms: D000328:Adult; D001513:Beds; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008170:Lung Compliance; D008297:Male; D008875:Middle Aged; D011175:Positive-Pressure Respiration / Q000379:methods*; D011187:Posture; D011379:Prognosis; D012128:Respiratory Distress Syndrome / Q000150:complications / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D013997:Time Factors; D014947:Wounds and Injuries / Q000150:complications*
vernacular_title: Posttraumatisches akutes Lungenversagen. Behandlung durch drucklimitierte Beatmung und kontinuierlichen Lagewechsel.