[The diagnosis of fatty dystrophy of the liver in fresh, formalin-treated and putrefactive cadaveric material].
In the course of investigation it was stated that fat hepatic dystrophy can be diagnosed by biochemical method (lipid extraction by hexane). For al this the content of extracted lipids more than 20% of dry residue evidences about the presence of fat hepatic dystrophy which is confirmed by histological detection of lipid granules whose quantity is increasing from fat dystrophy I degree (lipid content amounts up to 30% of dry residue) to fat dystrophy III degree (lipid content is more than 40%). Formalin treatment doesn't produce significant changes in lipid content and doesn't prevent biochemical diagnosis of fat dystrophy of the liver. In case of putrefied liver lipid content is increased slightly but in all periods of putrefaction lipid content in the liver in case of fat dystrophy remains significantly higher than in controls. Biochemical method may be used in diagnosis of fat hepatic dystrophy and its degree not only on fresh and formalin-treated cadaveric material but also in case of markedly pronounced putrefactive changes when other methods are useless and this fact is of great value for medicolegal practice.
Purdiaev
Iu S
IuS
Alisievich
V I
VI
D001834:Body Water / Q000378:metabolism; D002102:Cadaver; D005234:Fatty Liver / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology; D005557:Formaldehyde / Q000494:pharmacology*; D006651:Histocytochemistry; D006801:Humans; D050356:Lipid Metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism / Q000473:pathology*; D009132:Muscles / Q000378:metabolism / Q000473:pathology; D011180:Postmortem Changes; D014021:Tissue Preservation
D005557:Formaldehyde
Diagnostika zhirovoĭ distrofii pecheni na svezhem, formalinovom i gnilostno izmenennom trupnom materiale.