title: [Insulin effect on lipidemia and immunological indices in diabetes mellitus type 1].
abstract: Biochemical and immunologic studies were carried out in 361 patients with diabetes mellitus type I treated with large nonphysiological doses of insulin and physiological ones. Atherosclerosis and noticeable changes in lipid serum spectrum, immunity derangement occurred significantly more often in heparin overtreatment suggesting a conclusion on a possible role of chronic insulin overdosing in mechanisms of atherosclerosis development in diabetics.
authors.forename: E I
authors.initials: EI
authors.lastname: Krasil'nikova
authors.forename: Ia V
authors.initials: IaV
authors.lastname: Blagosklonnaia
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001161:Arteriosclerosis / Q000097:blood / Q000209:etiology* / Q000276:immunology; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000209:etiology* / Q000276:immunology; D007328:Insulin / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged
chemical_list: D007328:Insulin
vernacular_title: Vliianie insulina na lipidemiiu i immunologicheskie pokazateli pri sakharnom diabete 1 tipa.