A new balanced operation for complex gastroesophageal reflux disease.
Twenty-seven patients with advanced gastroesophageal reflux disease have been treated with combined transthoracic parietal cell vagotomy and Collis-Nissen fundoplication. Gastric acid analyses (n = 20) obtained preoperatively and 6 months postoperatively demonstrated a significant late reduction in gastric acid output. Twenty-six patients (96%) have experienced relief of gastroesophageal reflux disease at a mean of 13.3 months (range, 6 to 25 months) without postvagotomy symptoms. Transthoracic parietal cell vagotomy may be considered as an adjunct to mechanical surgical control of advanced gastroesophageal reflux disease.
Landreneau
R J
RJ
Division of Cardiothoracic Surgery, University of Missouri School of Medicine, Columbia.
Marshall
J B
JB
Johnson
J A
JA
Boley
T M
TM
Hazelrigg
S R
SR
Curtis
J J
JJ
McClelland
R N
RN
D000328:Adult; D000368:Aged; D004947:Esophagus / Q000601:surgery*; D005260:Female; D005748:Gastric Fundus / Q000601:surgery*; D005764:Gastroesophageal Reflux / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013908:Thoracotomy / Q000379:methods; D014629:Vagotomy, Proximal Gastric