title: [Detection of nootropic activity indicated by acute inhibition of orientation reaction].
abstract: Exploratory locomotor activity was studied in the experiments on adult male mice. It was shown that routine nootropic drugs as well as newly synthesized nootropic compounds were able to facilitate the development of inhibition during one registration session. Inhibition may be used for revealing only selective nootropic drugs devoid of sedative and stimulating effects.
authors.forename: R U
authors.initials: RU
authors.lastname: Ostrovskaia
authors.forename: T A
authors.initials: TA
authors.lastname: Gudasheva
mesh_terms: D000818:Animals; D005106:Exploratory Behavior / Q000187:drug effects*; D006185:Habituation, Psychophysiologic / Q000187:drug effects; D007266:Inhibition, Psychological; D008297:Male; D002504:Meclofenoxate / Q000494:pharmacology; D051379:Mice; D009949:Orientation / Q000187:drug effects*; D010889:Piracetam / Q000031:analogs & derivatives / Q000494:pharmacology; D011619:Psychotropic Drugs / Q000494:pharmacology*; D011746:Pyrithioxin / Q000494:pharmacology
chemical_list: D011619:Psychotropic Drugs; D011746:Pyrithioxin; D002504:Meclofenoxate; D010889:Piracetam
vernacular_title: Vyiavlenie aktivnosti nootropov po pokazateliu ostrogo ugashcheniia orientirovochnoĭ reaktsii.