[Effect of hypotensive treatment on renal function in patients with pseudo-hypertension].
Osler's maneuver which makes it possible to detect phenomenon of pseudo-hypertension was performed in 64 patients with elevated blood pressure when measured by Korotkoff's method. In 14 patients with essential hypertension and 14 patients with pseudo-hypertension the effect of 9 days hypotensive treatment with furosemide on renal function was compared. 22% of studied patients revealed pseudo-hypertension. The drop in arterial pressure caused a significant increase in the plasma urea, as well as a significant decrease in creatinine clearance and uric acid clearance in patients with pseudo-hypertension. These changes were not observed in patients with essential hypertension. Antihypertensive treatment of patients with pseudo-hypertension is hazardous due to the possibility of adverse effects caused by diminished tissue flow. Before starting the hypotensive therapy in elderly patients it is advisable to exclude pseudo-hypertension by means of Osler's maneuver.
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Kliniki Nadciśnienia Tetniczego Akademii Medycznej w Poznaniu.
D000368:Aged; D003404:Creatinine / Q000097:blood; D005260:Female; D005665:Furosemide / Q000627:therapeutic use*; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy*; D007668:Kidney / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D014508:Urea / Q000097:blood
D005665:Furosemide; D014508:Urea; D003404:Creatinine
Wpływ leczenia hipotensyjnego na czynność nerek u chorych z pseudonadciśnieniem tetniczym.