[Dynamic anti-Proteus immunity in plasma donors during plasmapheresis].
A study is presented of homeostasis in 18 volunteer donors after immunisation with Proteus vaccine and in the dynamics of subsequent plasmapheresis for 12 months. It was shown that as a result of anti-Proteus immunisation there occurs an increase of the titer of anti-Proteus antibodies in the blood serum which was maintained at a high level in the course of plasmapheresis for three months. Indices of the peripheral blood, urine, liver function, humoral unspecific and cellular immunity were within normal levels. The blood of donors immunized with Proteus vaccine is a source of obtaining anti-Proteus plasma--an immune allogenous preparation for complex treatment of patients with severe forms of diseases of Proteus etiology.
Nazarchuk
L V
LV
Fedorovskaia
E A
EA
D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood; D001428:Bacterial Vaccines / Q000276:immunology*; D001782:Blood Donors; D006801:Humans; D007109:Immunity / Q000276:immunology; D007114:Immunization; D007136:Immunoglobulins / Q000032:analysis; D010587:Phagocytosis / Q000276:immunology; D010949:Plasma / Q000276:immunology*; D010956:Plasmapheresis; D011513:Proteus mirabilis / Q000276:immunology*
D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines; D007136:Immunoglobulins
Dinamika antiproteĭnogo immuniteta donorov plazmy v protsesse plazmafereza.