[Effect of vasopressin and indomethacin on provoked diuresis in pregnant and non-pregnant Meriones crassus].
The dynamics of induced diuresis was studied in Meriones crassus, a desert rodent species, during estrus and pregnancy. In response to hydration, pregnant Meriones crassus excrete excess water more rapidly than non pregnant females. Diuresis appears earlier in pregnant females indicating a more rapid inactivation of vasopressin. The possible interaction between vasopressin and prostaglandins, and its effect on renal excretion during pregnancy, was studied during arginine-vasopressin treatment and after inhibition of endogenous AVP and prostaglandins. Results show a decrease in renal response to endogenous vasopressin during pregnancy in Meriones crassus, which may be due to the increase in renal prostaglandin levels.
Baddouri
K
K
Université Mohammed V, faculté des sciences, laboratoire de physiologie animale, Rabat, Maroc.
Quyou
A
A
D000818:Animals; D004231:Diuresis / Q000187:drug effects*; D005260:Female; D005849:Gerbillinae / Q000502:physiology*; D007213:Indomethacin / Q000494:pharmacology*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000502:physiology*; D011453:Prostaglandins / Q000502:physiology; D014667:Vasopressins / Q000494:pharmacology*
D011453:Prostaglandins; D014667:Vasopressins; D007213:Indomethacin
Effet de la vasopressine et de l'indométhacine sur la diurèse provoquée chez Meriones crassus gravide et non gravide.