title: Identification of peroxyacetic acid uroporphyrin I in the urine of patients with congenital erythropoietic porphyria by liquid chromatography and mass spectrometry.
abstract: A new porphyrin, peroxyacetic acid uroporphyrin I, has been isolated from the urine of patients with congenital erythropoietic porphyria by reversed phase high performance liquid chromatography. The porphyrin was characterized by high resolution mass spectrometry and by typical chemical reactions of a peroxyacid.
authors.affiliation: Division of Clinical Cell Biology, MRC Clinical Research Centre, Harrow, Middlesex, UK.
authors.forename: R
authors.initials: R
authors.lastname: Guo
authors.forename: J M
authors.initials: JM
authors.lastname: Rideout
authors.forename: W
authors.initials: W
authors.lastname: Chai
authors.forename: A M
authors.initials: AM
authors.lastname: Lawson
authors.forename: C K
authors.initials: CK
authors.lastname: Lim
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods; D015394:Molecular Structure; D011164:Porphyrias / Q000151:congenital / Q000652:urine*; D014578:Uroporphyrins / Q000302:isolation & purification / Q000652:urine*
chemical_list: D014578:Uroporphyrins; C070230:peroxyacetic acid uroporphyrin I