title: Cold swimming stress: effects on serum lipids, lipoproteins and LCAT activity in male and female rats.
abstract: Effects of consistent cold swimming stress on lipid and lipoprotein metabolism parameters were studied using male and female rats over a period of 60 and 20 days respectively. At the end of treatment serum total cholesterol, high density lipoproteins (HDL-C) and lecithin:cholesterol acetyltransferase (LCAT) activity declined in both male and female rats. TC/HDL-C ratio declined in 20 days in females, while in males it did not change. Free fatty acids increased, while triglycerides remained unchanged in both sexes. %Lipoprotein distribution in male animals did not show any phenotype alteration except in the group of 40 days where %VLDL declined and %LDL-C increased. Body weights did not change, except in males in 60 days. Consistent cold swimming stress by lowering HDL-C and LCAT activity seems to influence lipoprotein metabolism.
authors.affiliation: Department of Experimental Physiology, Athens University Medical School, Greece.
authors.forename: C
authors.initials: C
authors.lastname: Tsopanakis
authors.forename: C
authors.initials: C
authors.lastname: Tesserommatis
mesh_terms: D000818:Animals; D003080:Cold Temperature; D005260:Female; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D007862:Phosphatidylcholine-Sterol O-Acyltransferase / Q000097:blood*; D051381:Rats; D011919:Rats, Inbred Strains; D013312:Stress, Physiological / Q000097:blood*; D013550:Swimming; D013997:Time Factors
chemical_list: D008055:Lipids; D008074:Lipoproteins; D007862:Phosphatidylcholine-Sterol O-Acyltransferase