title: [Allergic granulomatous nodule of the conjunctiva disclosing onchocerciasis].
abstract: A new case of conjunctival allergic nodule is reported in a Guinean man. This lesion was first described by Ashton and Cook in 1979. Histologically, this nodule consists of amorphous eosinophilic material surrounded by epithelioid and giant cells arranged in a pallisade; some eosinophils are often found in the inflammatory reaction. This lesion usually resolves spontaneously. In documented cases, nematodes and particularly filaria such as Mansonella perstans are usually isolated. Our observation is the first documented case with Onchocerca volvulus. Microfilariae were detected by examination of normal saline containing the biopsy specimen. The new major antifilarial treatment ivermectin was associated.
authors.affiliation: Service de Microbiologie, Hôtel Dieu de Paris, France.
authors.forename: D
authors.initials: D
authors.lastname: Basset
authors.forename: F
authors.initials: F
authors.lastname: D'Hermies
authors.forename: Y
authors.initials: Y
authors.lastname: Pouliquen
authors.forename: P H
authors.initials: PH
authors.lastname: Lagrange
mesh_terms: D000328:Adult; D003229:Conjunctival Diseases / Q000209:etiology* / Q000469:parasitology / Q000473:pathology; D004803:Eosinophilic Granuloma / Q000209:etiology* / Q000469:parasitology / Q000473:pathology; D006801:Humans; D008297:Male; D015827:Onchocerciasis, Ocular / Q000150:complications* / Q000469:parasitology / Q000473:pathology
vernacular_title: Nodule granulomateux allergique de la conjonctive révélateur d'une onchocercose.