Peptide tyrosine tyrosine-positive ovarian carcinoid tumor arising from a dermoid cyst.
A case of ovarian carcinoid tumor of the trabecular type is presented. The small carcinoid tumor was found incidentally in a resected dermoid cyst. Histologically, the tumor was surrounded by a smooth muscle layer with focal stromal invasion. Non-carcinoid papillary mucosa and a few small glands, simulating the mucosa of the fallopian tube and remnant müllerian glands, respectively, were also present adjacent to the carcinoid tumor and enclosed by the same smooth muscle layer. The tumor cells revealed argyrophilia, and were positive for peptide tyrosine tyrosine (PYY) in the cytoplasm and for CEA in part of the luminal surface. This case was considered to be a rare ovarian carcinoid tumor arising from a dermoid cyst, without association of struma ovarii. PYY may be a potential marker for determining the histogenesis of ovarian carcinoid tumors.
Fukuda
T
T
Second Department of Pathology, Niigata Minami Hospital, Japan.
Ohnishi
Y
Y
Terashima
T
T
Iwafuchi
M
M
Itoh
S
S
D000328:Adult; D002272:Carcinoembryonic Antigen / Q000032:analysis; D002276:Carcinoid Tumor / Q000737:chemistry / Q000473:pathology*; D003884:Dermoid Cyst / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000737:chemistry / Q000473:pathology*; D019894:Peptide YY; D010455:Peptides / Q000032:analysis*
D002272:Carcinoembryonic Antigen; D010455:Peptides; D019894:Peptide YY