Cystic adrenal masses in the neonate associated with hemihypertrophy and the relation to the Beckwith-Wiedemann syndrome.
We report 2 cases of unilateral, multilocular, cystic adrenal masses in neonates. Both patients demonstrated somatic hemihypertrophy, which is considered to have the same implications as the Beckwith-Wiedemann syndrome in terms of tumor risk. Pathological examination showed multiple, adrenal cysts without evidence of tumor or routine adrenal hemorrhage. This finding appears to represent a previously unreported association between the spectrum of hemihypertrophy/Beckwith-Wiedemann syndrome and benign cystic adrenal disease.
Walton
G R
GR
Department of Urology, Babies Hospital, Columbia-Presbyterian Medical Center, New York, New York.
Peng
B C
BC
Berdon
W E
WE
Collins
M H
MH
Hensle
T W
TW
D000307:Adrenal Gland Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D001506:Beckwith-Wiedemann Syndrome / Q000150:complications*; D003560:Cysts / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D006984:Hypertrophy / Q000150:complications; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D014057:Tomography, X-Ray Computed