title: Proto-oncogene expression in cultured synovial fibroblasts of patients with rheumatoid arthritis.
abstract: Total RNA was isolated from cultured synovial fibroblasts of nine patients with rheumatoid arthritis and two controls (cruciate ligament ruptures). RNA was dot-blotted and hybridized with nine different, cloned cellular or viral oncogene probes. None of the proto-oncogenes showed a significant difference of expression in cultured fibroblasts from patients with rheumatoid arthritis when compared to the expression of control fibroblasts.
authors.affiliation: Abt. Biochemie, Robert Koch-Institut, Berlin, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Anders
authors.forename: K
authors.initials: K
authors.lastname: Krohn
authors.forename: H
authors.initials: H
authors.lastname: Kröger
authors.forename: H
authors.initials: H
authors.lastname: Huser
authors.forename: M
authors.initials: M
authors.lastname: Sparmann
authors.forename: A
authors.initials: A
authors.lastname: Meissner
authors.forename: W
authors.initials: W
authors.lastname: Gombert
mesh_terms: D001172:Arthritis, Rheumatoid / Q000235:genetics*; D015152:Blotting, Northern; D002455:Cell Division; D015342:DNA Probes; D005347:Fibroblasts / Q000378:metabolism; D015870:Gene Expression; D016259:Genes, myc; D011905:Genes, ras; D016391:Genes, src; D006801:Humans; D000090063:Proto-Oncogene Mas; D011519:Proto-Oncogenes / Q000235:genetics*; D012333:RNA, Messenger / Q000032:analysis; D013583:Synovial Membrane / Q000378:metabolism*
chemical_list: D015342:DNA Probes; C000715470:MAS1 protein, human; D000090063:Proto-Oncogene Mas; D012333:RNA, Messenger