title: Incidence of gallstones in liver cirrhosis.
abstract: We conducted a longitudinal follow-up of 72 patients with liver cirrhosis (LC) in order to assess gallstone (GS) incidence. The period of survey was 24.5 +/- 12.2 months. Patients were divided into two groups: group I--26 patients with ascites at the start or appearing during follow-up, and Group II--46 patients with compensated LC (no ascites) throughout the survey. During follow-up, 12 of 72 (16.6%) patients developed GS. The global cumulative incidence of GS was 5.5 cases/100 people/year. Age and sex had no influence on the incidence of GS in LC; neither had etiology or cirrhosis. On the contrary, the study revealed a significant increase in the incidence of GS in decompensated cirrhosis. In group I patients, GS appeared more frequently (34.6%) than in group II patients (6.5%) (chi 2 9.479; p less than 0.002). The cumulative incidence of GS was five times higher in decompensated versus compensated LC.
authors.affiliation: Third Medical Clinic, University of Medicine and Pharmacy, Romania.
authors.forename: M
authors.initials: M
authors.lastname: Acalovschi
authors.forename: R
authors.initials: R
authors.lastname: Badea
authors.forename: M
authors.initials: M
authors.lastname: Pascu
mesh_terms: D000328:Adult; D000368:Aged; D001201:Ascites / Q000150:complications*; D002769:Cholelithiasis / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D012383:Romania / Q000453:epidemiology