Serum lipid and apolipoprotein levels in non-hypertensive lean NIDDM patients.
To determine the possible role of a glycaemic control in lipid metabolism in non-insulin-dependent diabetes mellitus (NIDDM) patients, serum lipid and apolipoprotein levels were measured in well-controlled and poorly controlled lean NIDDM without proteinuria and hypertension. A sample of 96 lean NIDDM patients (body mass index less than 25 kg m-2 in men and less than 27 kg m-2 in women) were divided into two groups: group I, where the HbA1c concentration had been less than 6% for the previous 3 months, and group II, where the HbA1c concentration had been greater than 8% for the previous 3 months. Serum total cholesterol, triglyceride, and HDL-cholesterol levels showed no significant differences between groups I and II. Furthermore, serum levels of apolipoproteins AI, AII, B, CII, CIII, and E did not differ significantly between groups I and II. These results suggest that glycaemic control did not influence lipid metabolism in lean NIDDM patients.
Ikeda
T
T
First Department of Internal Medicine, Tottori University School of Medicine, Yonago, Japan.
Ochi
H
H
Ohtani
I
I
Fujiyama
K
K
Hoshino
T
T
Tanaka
Y
Y
Takeuchi
T
T
Mashiba
H
H
D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001053:Apolipoproteins / Q000097:blood*; D001786:Blood Glucose / Q000032:analysis*; D015992:Body Mass Index; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D005260:Female; D006801:Humans; D006973:Hypertension; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D011507:Proteinuria
D001053:Apolipoproteins; D001786:Blood Glucose; D008055:Lipids