title: Cis-platinum chemotherapy for ocular basal cell carcinoma.
abstract: We have used intravenous cis-platinum chemotherapy in the treatment of three patients with basal cell carcinoma of the lid extending into the orbit. Cis-platinum chemotherapy caused a reduction in tumour size and thereby delayed surgery in all cases. It allowed for local resection in one case, appeared to delay a patient's exenteration in a second case, and was used prior to radiotherapy in a third case. While not curative, cis-platinum may be useful as an adjuvant to decrease tumour mass prior to local excision and for patients who refuse or must delay exenteration.
authors.affiliation: Department of Ophthalmology, Manhattan Eye, Ear, and Throat Hospital, New York City.
authors.forename: M
authors.initials: M
authors.lastname: Morley
authors.forename: P T
authors.initials: PT
authors.lastname: Finger
authors.forename: M
authors.initials: M
authors.lastname: Perlin
authors.forename: L R
authors.initials: LR
authors.lastname: Weiselberg
authors.forename: D S
authors.initials: DS
authors.lastname: DeBlasio
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002280:Basal Cell Carcinoma / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use*; D005142:Eyelid Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D009361:Neoplasm Invasiveness; D009915:Orbit / Q000000981:diagnostic imaging; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed
chemical_list: D002945:Cisplatin