Kaposi's sarcoma in a child after autologous bone marrow transplantation for non-Hodgkin's lymphoma.
A case of Kaposi's sarcoma in a child with no serologic evidence of human immunodeficiency virus (HIV) infection is reported. A 7-year-old boy with Stage IV non-Hodgkin's lymphoma, after conventional chemotherapy, underwent autologous bone marrow transplantation (ABMT). Five months later he presented with supraclavicular mass and mediastinal enlargement. A bone marrow biopsy showed hypoplasia with no signs of the underlying disease, whereas the excised mass revealed a typical histologic pattern of Kaposi's sarcoma. The child is currently being treated with recombinant alpha-interferon (alpha-IFN) and regression of the disease has been achieved.
Porta
F
F
Department of Pediatrics, University of Pavia, IRCCS Policlinico S. Matteo, Italy.
Bongiorno
M
M
Locatelli
F
F
Gibardi
A
A
Lanfranchi
A
A
Rosso
R
R
Paulli
M
M
Nespoli
L
L
Burgio
G R
GR
D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002648:Child; D002968:Clavicle; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000601:surgery*; D012514:Sarcoma, Kaposi / Q000209:etiology* / Q000473:pathology