title: [Comparison of the bioequivalence of two allopurinol preparations].
abstract: Allopurinol generally is considered to be a problematic substance as to its bioavailability. To prove the quality, the in-vivo bioequivalence of an allopurinol (CAS 315-30-0) preparation (Cellidrin 300) in comparison to the standard preparation has been investigated. Both products were bioequivalent with regard to all relevant parameters such as AUC, tmax and Cmax.
authors.affiliation: McKnight Laboratories, Hamburg.
authors.forename: K
authors.initials: K
authors.lastname: Bührens
authors.forename: P
authors.initials: P
authors.lastname: Berndt
authors.forename: C M
authors.initials: CM
authors.lastname: Hilgenstock
authors.forename: W
authors.initials: W
authors.lastname: Baumann
authors.forename: D
authors.initials: D
authors.lastname: Janzen
mesh_terms: D000328:Adult; D000493:Allopurinol / Q000008:administration & dosage / Q000493:pharmacokinetics*; D001682:Biological Availability; D006801:Humans; D008297:Male; D013607:Tablets; D013810:Therapeutic Equivalency
chemical_list: D013607:Tablets; D000493:Allopurinol
vernacular_title: Zum Nachweis der Bioäquivalenz von zwei Allopurinol-Präparaten.