Magnetic resonance imaging of hyperbaric oxygen treated rats with spinal cord injury: preliminary studies.
Magnetic resonance imaging (MRI) has been performed to assess the efficacy of hyperbaric oxygen (HBO) treatment on experimental spinal cord injury in a rat animal model. A moderately severe injury, similar to Type III injury seen in humans (Kulkarni et al. Radiology 164:837;1987) has been chosen for these studies. An improvement in the neurologic recovery (based on Tarlov scale) has been observed following HBO treatment over a period of 72 hr. Based on MRI, HBO treatment appears to arrest the spread of hemorrhage and resolve edema.
Narayana
P A
PA
Department of Radiology, University of Texas Medical School, Houston 77030.
Kudrle
W A
WA
Liu
S J
SJ
Charnov
J H
JH
Butler
B D
BD
Harris
J H
JH
D000818:Animals; D006931:Hyperbaric Oxygenation; D008279:Magnetic Resonance Imaging; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013116:Spinal Cord / Q000473:pathology; D013119:Spinal Cord Injuries / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy