title: [Study of antimutagenic properties of bio-ginseng in mammalian cells in vitro and in vivo].
abstract: The impact was studied of bio-ginseng produced from ginseng callus cells on the rate of chromosome rearrangements in Chinese hamster cells and in continuous tumor cells of mice (Ehrlich strain). Bio-ginseng reduced rate of spontaneous SCE as well as the level of mitomycin C-induced chromosome aberrations in Chinese hamster cells. It protected ascitic tumor cells (Ehrlich strain) against the mutagen action of urea nitrosomethyl.
authors.forename: N V
authors.initials: NV
authors.lastname: Umnova
authors.forename: T L
authors.initials: TL
authors.lastname: Michurina
authors.forename: N I
authors.initials: NI
authors.lastname: Smirnova
authors.forename: I V
authors.initials: IV
authors.lastname: Aleksandrova
authors.forename: G G
authors.initials: GG
authors.lastname: Poroshenko
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D006224:Cricetinae; D003412:Cricetulus; D051379:Mice; D016296:Mutagenesis / Q000187:drug effects*; D005894:Panax; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D012854:Sister Chromatid Exchange; D014407:Tumor Cells, Cultured
chemical_list: D010936:Plant Extracts
vernacular_title: Izuchenie antimutagennykh svoĭstv biozhen'sheniia na kletkakh mlekopitaiushchikh in vitro i in vivo.