title: [Molecular biology studies of bladder cancer].
abstract: The mechanisms that control the biological behaviour of urothelial cancer are complex, and many regulative interactions are involved. So far, few aspects of these control mechanisms have been recognized and characterized. A precondition for better understanding is knowledge the interaction of this factors. Some markers (e.g., chromosomal aberrations, EGFR expression) are correlated with progression of tumour. Whether they are the cause or the result of the aggressive behaviour of growth remains unknown. Only a few markers, especially in flow cytometry, will have any benefit in clinical routine. Whether it is possible to find a marker with prognostic value remains uncertain.
authors.affiliation: Urologische Abteilung, Universitätsklinik, Nijmegen, Niederlande.
authors.forename: P P
authors.initials: PP
authors.lastname: Bringuier
authors.forename: H J
authors.initials: HJ
authors.lastname: Knopf
authors.forename: J A
authors.initials: JA
authors.lastname: Schalken
authors.forename: F M
authors.initials: FM
authors.lastname: Debruyne
mesh_terms: D000782:Aneuploidy; D014408:Biomarkers, Tumor / Q000235:genetics; D001706:Biopsy; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis / Q000235:genetics*; D002471:Cell Transformation, Neoplastic / Q000235:genetics*; D004273:DNA, Neoplasm / Q000235:genetics; D015972:Gene Expression Regulation, Neoplastic / Q000502:physiology*; D006801:Humans; D011379:Prognosis; D001743:Urinary Bladder / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000235:genetics*
chemical_list: D014408:Biomarkers, Tumor; D004273:DNA, Neoplasm
vernacular_title: Molekularbiologische Untersuchungen beim Blasenkarzinom.