title: [Prevention of myocardial infarction by reducing serum cholesterol levels. High-risk strategies should be limited].
abstract: Prevention of premature myocardial infarction is an important public health issue. Two different approaches may be used in order to prevent premature myocardial infarction, a high-risk strategy and a population strategy. The report discusses prevention of myocardial infarction in middle-aged Norwegian individuals by reducing total serum cholesterol and using the high risk and population strategies. A combination of these strategies is recommended, but with major emphasis on the population approach. Both trials and calculations indicate that the high-risk strategy should be limited to subjects with very high serum cholesterol (e.g. greater than or equal to 8 mmol/l in middle-aged men).
authors.affiliation: Institutt for samfunnsmedisin, Universitetet i Tromsø.
authors.forename: B K
authors.initials: BK
authors.lastname: Jacobsen
mesh_terms: D000328:Adult; D002784:Cholesterol / Q000097:blood*; D006801:Humans; D006937:Hypercholesterolemia / Q000517:prevention & control* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000517:prevention & control*; D009664:Norway; D012307:Risk Factors; D014434:Type A Personality
chemical_list: D002784:Cholesterol
vernacular_title: Forebygging av hjerteinfarkt ved reduksjon av serum-kolesterolkonsentrasjonen. Høyrisikostrategien bør begrenses til de få.