[Relationship between decreased presynaptic inhibition and muscle spasticity in patients with a history of cerebral insult].
Stimulation electromyography was used to study inhibition of the soleus muscle H-reflex induced by stimulation of the common peroneal nerve in healthy individuals and in patients who had underwent cerebral apoplexy. Two successive inhibition waves (D1 and D2) were recorded; the first wave demonstrated the development of presynaptic inhibition of group Ia afferent fibers. In post-insult patients the depth of inhibition diminished depending on the degree of the pathologic increase of the tonus of the skeletal musculature. The role of presynaptic inhibition disorders in the pathogenesis of muscle spasticity is discussed.
Brazhnikov
A N
AN
Gaft
P G
PG
Kaperko
V P
VP
Kotlik
B A
BA
Krivtsova
E S
ES
Slivko
E I
EI
Teplova
L N
LN
Shevchenko
L A
LA
D002561:Cerebrovascular Disorders / Q000503:physiopathology*; D006801:Humans; D009128:Muscle Spasticity / Q000503:physiopathology*; D009433:Neural Inhibition / Q000502:physiology*
Zavisimost' mezhdu oslableniem presinapticheskogo tormozheniia i myshechnoĭ spastichnost'iu u bol'nykh, perenesshikh mozgovoĭ insul't.