[Effect of estrogens on the free fatty acid content and fatty acid-binding protein fractions in rabbit intestinal mucosa].
A study was made of the effect of ovariectomy and administration of estradiol-dipropionate on the level of estrogen receptors, low molecular protein fractions, incorporating fatty acid binding proteins (FABP), and free fatty acids (FFA) in the protein fractions of the cytosol of the intestinal mucosa of mature and immature female rabbits. The female rabbit upper intestinal mucosa was shown to possess cytoplasmic estrogen receptors and to have low metabolic activity of estradiol dehydrogenase (not being target tissue). Ovariectomy caused a decrease in the level of estrogen receptors, protein fractions, incorporating FABP, and FFA in them in enterocyte mucosa cytosol as compared to respective parameters in female rabbits in the pubertal and mature periods of their development. Estrogens were involved in the regulation of the level of intestinal fatty acid binding protein fractions and in ensuring physiological concentrations of absorbed fatty acids.
Bogdarin
Iu A
IuA
D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism*; D004958:Estradiol / Q000502:physiology*; D050556:Fatty Acid-Binding Proteins; D005230:Fatty Acids, Nonesterified / Q000378:metabolism*; D005260:Female; D007413:Intestinal Mucosa / Q000378:metabolism*; D008970:Molecular Weight; D009363:Neoplasm Proteins; D010052:Ovariectomy; D010053:Ovary / Q000502:physiology*; D011485:Protein Binding; D011817:Rabbits; D011960:Receptors, Estrogen / Q000378:metabolism*; D012741:Sexual Maturation / Q000502:physiology
D002352:Carrier Proteins; D050556:Fatty Acid-Binding Proteins; D005230:Fatty Acids, Nonesterified; D009363:Neoplasm Proteins; D011960:Receptors, Estrogen; D004958:Estradiol
Vliianie éstrogenov na soderzhanie svobodnykh zhirnykh kislot i fraktsiĭ sviazyvaiiushchikh ikh belkov i slizistoĭ tonkoĭ kishki krolikov.