title: [An electrolyte-adapted heparin solution for the determination of blood gases and electrolytes in whole blood].
abstract: Blood gases, pH, sodium, potassium, chloride, and ionised calcium in whole blood samples can be determined simultaneously in modern instruments. Preparing syringes with conventional heparin solutions causes a relevant bias of the electrolyte concentrations (especially K+ and Ca2+) by dilution of the sample. Additionally, ionised calcium is decreased by binding to heparin. The solution described in the present paper yields a final heparin concentration of 4-6 mU/l, thus eliminating the calcium binding effect. The dilution effects are antagonised by an electrolyte composition that is similar to normal plasma. The heparin solution is commercially available.
authors.affiliation: Zentrallaboratorium des Allgemeinen Krankenhauses Altona in Hamburg.
authors.forename: O
authors.initials: O
authors.lastname: Müller-Plathe
authors.forename: R
authors.initials: R
authors.lastname: Schreiber
mesh_terms: D001784:Blood Gas Analysis / Q000379:methods*; D004573:Electrolytes / Q000097:blood*; D006493:Heparin; D006801:Humans; D012996:Solutions
chemical_list: D004573:Electrolytes; D012996:Solutions; D006493:Heparin
vernacular_title: Eine elektrolytadaptierte Heparinlösung für die Bestimmung der Blutgase und der Elektrolyte im Vollblut.