title: Modulations in nitrogen metabolism in the hepatic and neuronal tissues of fish, Tilapia mossambica exposed to atrazine.
abstract: The present study deals with the effect of atrazine on nitrogen metabolism in the liver and brain of fish. Significant changes were seen in the levels of proteins, free amino acids, ammonia, urea, glutamine and the activity levels of proteases, glucogenic aminotransferases, branched-chain aminotransferases, glutamate dehydrogenase, glutaminase, arginase, AMP deaminase and adenosine deaminase in both the tissues of fish exposed to sublethal concentration of atrazine. The study reflects a shift in nitrogen concentration of atrazine. The study reflects a shift in nitrogen metabolism in the tissues of fish for efficient mobilization of end products of protein catabolism as a consequence of atrazine.
authors.affiliation: Department of Zoology, Sri Venkateswara University, Tirupati, India.
authors.forename: T A
authors.initials: TA
authors.lastname: Prasad
authors.forename: T
authors.initials: T
authors.lastname: Srinivas
authors.forename: D C
authors.initials: DC
authors.lastname: Reddy
mesh_terms: D000596:Amino Acids / Q000378:metabolism; D000641:Ammonia / Q000378:metabolism; D000818:Animals; D001280:Atrazine / Q000494:pharmacology*; D001921:Brain / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D005399:Fishes / Q000378:metabolism*; D005973:Glutamine / Q000378:metabolism; D008099:Liver / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D009584:Nitrogen / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism; D014508:Urea / Q000378:metabolism
chemical_list: D000596:Amino Acids; D011506:Proteins; D005973:Glutamine; D000641:Ammonia; D014508:Urea; D009584:Nitrogen; D001280:Atrazine