[Diagnostic and prognostic significance of anti-HBCAG IgM in hepatitis B and its outcomes].
Enzyme immunoassay was employed to investigate HBV markers (HBsAg, HBeAg, IgM anti-HBc, anti-HBc, anti-HBs) in 126 patients suffering from viral hepatitis B. It was noted that IgM anti-HBc appeared in ++pre-jaundice period in 100% of the examinees. In case of hepatitis transformation into a chronic form the titers of IgM anti-HBc depended on the disease activity, their high concentration being typical for the stage of active virus replication.
Fedorchenko
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D000293:Adolescent; D000328:Adult; D000368:Aged; D000914:Antibodies, Viral / Q000032:analysis / Q000276:immunology*; D006509:Hepatitis B / Q000150:complications / Q000175:diagnosis / Q000276:immunology*; D006512:Hepatitis B Core Antigens / Q000032:analysis / Q000276:immunology*; D006521:Hepatitis, Chronic / Q000175:diagnosis / Q000209:etiology / Q000276:immunology*; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis / Q000276:immunology*; D008875:Middle Aged; D011379:Prognosis; D012720:Severity of Illness Index
D000914:Antibodies, Viral; D006512:Hepatitis B Core Antigens; D007075:Immunoglobulin M
Diagnosticheskoe i prognosticheskoe znachenie IgM anti-HBc pri virusnom gepatite B i ego iskhodakh.