[Function of the pentosephosphate pathway in the rat brain during one-time administration of various doses of ethanol].
A rate of alterations in the enzymatic activity of pentosephosphate pathway and content of glucose in rat brain depended on a dose of administered ethanol. The alcohol inhibitory effect on the enzymatic activity was localized mainly in the brain steam. Impairment of the pentosephosphate pathway functions in alcohol intoxication demonstrated the pathway importance in realization of ethanol effects in nervous tissue.
Lelevich
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D000818:Animals; D001921:Brain / Q000201:enzymology / Q000378:metabolism*; D000431:Ethanol / Q000008:administration & dosage / Q000633:toxicity*; D005954:Glucosephosphate Dehydrogenase / Q000037:antagonists & inhibitors / Q000378:metabolism; D008297:Male; D010427:Pentose Phosphate Pathway / Q000502:physiology*; D010734:Phosphogluconate Dehydrogenase / Q000037:antagonists & inhibitors / Q000378:metabolism; D051381:Rats; D014174:Transketolase / Q000037:antagonists & inhibitors / Q000378:metabolism
D000431:Ethanol; D010734:Phosphogluconate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D014174:Transketolase
Funktsionirovanie pentozofosfatnogo puti v golovnom mozge krys pri odnokratnom vvedenii razlichnykh doz étanola.