Tuberculin skin-test-induced uveitis in the absence of tuberculosis.
A 16-year-old Caucasian girl who showed no evidence of tuberculosis or other systemic disease developed acute panuveitis progressing to bilateral serous retinal detachments following purified protein derivative (PPD) skin testing on two separate occasions separated by an interval of 8 years. Both episodes responded rapidly to steroid therapy. Uveal hypersensitivity to PPD skin testing has been described in the presence of ocular or systemic tuberculosis, Eales' disease, and the Vogt-Koyanagi-Harada syndrome (VKH). Our case, however, suggests that profound uveitis may be precipitated by routine PPD skin testing alone.
Burgoyne
C F
CF
Eye Institute, University of Pittsburgh School of Medicine, Department of Ophthalmology, PA 15213.
Verstraeten
T C
TC
Friberg
T R
TR
D000293:Adolescent; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D015864:Panuveitis / Q000188:drug therapy / Q000209:etiology*; D011241:Prednisone / Q000008:administration & dosage; D012163:Retinal Detachment / Q000188:drug therapy / Q000209:etiology; D014374:Tuberculin Test / Q000009:adverse effects*; D014376:Tuberculosis / Q000175:diagnosis*
D011241:Prednisone