title: [Can choice of medications and adjuvants reduce risks of local anesthetic complications?].
abstract: Local anesthetic agents in high concentrations may cause local irritation by ischemia especially after the use of adrenaline whereas felypressin has no tissue-irritating properties. Adrenaline but not felypressin increases the intravenous systemic toxicity. Noradrenaline has to be avoided as a vasoconstrictor. An aspiration test before injection will decrease the risk of inadvertent intravenous injection.
authors.affiliation: St. Marien- und St. Annastiftskrankenhaus.
authors.forename: H C
authors.initials: HC
authors.lastname: Niesel
authors.forename: H
authors.initials: H
authors.lastname: Kaiser
mesh_terms: D000759:Adjuvants, Anesthesia / Q000633:toxicity; D000771:Anesthesia, Intravenous; D000779:Anesthetics, Local / Q000633:toxicity*; D000818:Animals; D004837:Epinephrine / Q000633:toxicity*; D005259:Felypressin / Q000633:toxicity*; D051379:Mice; D014662:Vasoconstrictor Agents / Q000633:toxicity*
chemical_list: D000759:Adjuvants, Anesthesia; D000779:Anesthetics, Local; D014662:Vasoconstrictor Agents; D005259:Felypressin; D004837:Epinephrine
vernacular_title: Kann durch die Auswahl von Medikamenten und Adjuvantien das Komplikationsrisiko von Lokalanästhesien gesenkt werden?