title: Toxic effects of drugs used in the ICU. Antiarrhythmic agents.
abstract: Supraventricular and ventricular arrhythmias remain relatively commonplace in the ICU. Proper pharmacologic treatment requires that the clinician recognize accompanying disease states that may alter the pharmacokinetics and pharmacodynamics of antiarrhythmic drugs. In addition, knowledge of cardiovascular toxicity, noncardiovascular adverse effects, and drug-drug interactions are necessary to optimize antiarrhythmic drug therapy.
authors.affiliation: Department of Pharmacy Practice, University of Arizona, College of Pharmacy, Tucson.
authors.forename: P E
authors.initials: PE
authors.lastname: Nolan
authors.forename: C L
authors.initials: CL
authors.lastname: Raehl
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000009:adverse effects* / Q000494:pharmacology / Q000627:therapeutic use; D001145:Arrhythmias, Cardiac / Q000188:drug therapy; D003422:Critical Care; D004347:Drug Interactions; D006801:Humans; D007362:Intensive Care Units
chemical_list: D000889:Anti-Arrhythmia Agents