Biogenic amines and ascorbic acid in rat brain following steroid contraceptive treatment.
Chronic treatment with steroid contraceptive produced a decrease in dopamine and norepinephrine concentration in discrete brain areas and an increase in ascorbic acid level. We suggest that alteration in the level of biogenic amines by steroid contraceptive may have some functional correlation with the ascorbic acid concentration in rat brain.
Dey
C D
CD
Department of Physiology, Calcutta University College of Science and Technology, India.
Das
P C
PC
Das
K
K
Patra
P B
PB
Dasgupta
S
S
D000818:Animals; D001205:Ascorbic Acid / Q000378:metabolism*; D001679:Biogenic Amines / Q000378:metabolism*; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D002531:Cerebellum / Q000378:metabolism; D002540:Cerebral Cortex / Q000378:metabolism; D003278:Contraceptives, Oral, Hormonal / Q000494:pharmacology*; D004298:Dopamine / Q000378:metabolism; D004997:Ethinyl Estradiol / Q000494:pharmacology*; D019304:Ethinyl Estradiol-Norgestrel Combination; D005260:Female; D006624:Hippocampus / Q000378:metabolism; D007031:Hypothalamus / Q000378:metabolism; D008526:Medulla Oblongata / Q000378:metabolism; D009638:Norepinephrine / Q000378:metabolism; D009644:Norgestrel / Q000494:pharmacology*; D011149:Pons / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013788:Thalamus / Q000378:metabolism
D001679:Biogenic Amines; D003278:Contraceptives, Oral, Hormonal; D009644:Norgestrel; D004997:Ethinyl Estradiol; D019304:Ethinyl Estradiol-Norgestrel Combination; D001205:Ascorbic Acid; D004298:Dopamine; D009638:Norepinephrine