[The quantitative analysis of thyroid hormones and thyrotropin in children critically ill with septicemia].
The function of the hypothalamus, hypophysis, and thyroid glands was studied in 23 critically-ill septicemic children and 15 other healthy children used as controls. A comparison in the quantification of 3,3'5-triiodothyronine (T3), 3,3',5'triiodothyronine (T3r), thyroxine (T4) and thyrotropin (TSH) from those in the control group with the initial values from the patients showed a notable decrease of T3 and T4 and a rise in T3r and TSH in the septicemic children, with a statistical significant difference (P less than 0.001). These biochemical changes which translate into a homeostatic command to avoid catabolism through the conservation of energy, spontaneously returned to normal in 18 of the surviving septicemic children once they recuperated.
Mendoza-Morfín
F
F
Departamento de Endocrinología Pediátrica, Hospital General, Centro Médico La Raza, México, D.F.
Vaca-Arellano
M R
MR
Toledo-Villalpando
A D
AD
Olvera-Hidalgo
C
C
Mondragón-Rosales
L
L
Junco-Lorenzana
E
E
D000208:Acute Disease; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011863:Radioimmunoassay; D018805:Sepsis / Q000097:blood*; D013963:Thyroid Hormones / Q000097:blood*; D013972:Thyrotropin / Q000097:blood*
D013963:Thyroid Hormones; D013972:Thyrotropin
Cuantificación de hormonas tiroideas y tirotropina en niños críticamente enfermos con septicemia.