Oral contraceptives and skin neoplasia.
A possible association between oral contraception and the development of cutaneous melanoma has been raised largely because of the hyperpigmentation of pregnancy and the effect pregnancy may have on the outcome of established disease. Present evidence suggests there is no causal link between oral contraceptive (OC) use and melanoma (or with benign melanocytic nevi), nor has a specific subgroup of women or subtype of melanoma been consistently implicated as being at increased risk of this disease due to use of OCs.
Green
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Queensland Institute of Medical Research, Brisbane, Australia.
D000367:Age Factors; D016022:Case-Control Studies; D015331:Cohort Studies; D003276:Contraceptives, Oral / Q000009:adverse effects; D005260:Female; D006801:Humans; D008545:Melanoma / Q000139:chemically induced / Q000453:epidemiology / Q000209:etiology*; D009506:Nevus / Q000139:chemically induced / Q000453:epidemiology / Q000209:etiology; D012307:Risk Factors; D012878:Skin Neoplasms / Q000139:chemically induced / Q000453:epidemiology / Q000209:etiology*
D003276:Contraceptives, Oral