Isolation and characterization of new allosamidins.
Three of new allosamidins, termed glucoallosamidins A (5), B (6) and methyl-N-demethyl-allosamidin (4), were isolated as yeast chitinase inhibitors from the mycelium of Streptomyces sp. SA-684.
Nishimoto
Y
Y
Department of Biotechnology, Faculty of Engineering, Osaka University, Japan.
Sakuda
S
S
Takayama
S
S
Yamada
Y
Y
D000117:Acetylglucosamine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002176:Candida albicans / Q000201:enzymology; D002688:Chitinases / Q000037:antagonists & inhibitors*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D012441:Saccharomyces cerevisiae / Q000201:enzymology; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013302:Streptomyces / Q000378:metabolism; D014242:Trichoderma / Q000201:enzymology; D014312:Trisaccharides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*
D000935:Antifungal Agents; D014312:Trisaccharides; C054851:allosamidin; C070537:methyl-N-demethylallosamidin; C070535:glucoallosamidin A; C070536:glucoallosamidin B; D002688:Chitinases; D000117:Acetylglucosamine