[The effects of passive smoking on health].
Our experiments were conducted on rabbits. In order to study the effects of passive smoking on the health, smokers were exposed to cigarette smoke for 30 days. Cigarette dosimetry is equivalent to two packs per day in man. The experimental results as follows. 1. There is a significant amount of Cotinine (0.69 microgram/ml) in the blood of passive smoking rabbits. 2. There is a lot of Benzpyrene (0.59 microgram/ml) in the BALF of passive smoking rabbits. 3. The level of histamine in BALF increased more than that of control group. 4. The level of TXB2 increased and the level of 6-keto-PGF1 alpha decreased in the blood of passive smoking rabbits more than that of the control group. 5. The level of elastase in the blood and the O2- production of alveolar macrophages of passive smoking rabbits are more than that of the control group. These results showed that passive smoking may increase the occurrence and development of COPD and cardiovascular disease as well.
Du
B Y
BY
Beijing Red Cross Chao Yang Hospital.
D000818:Animals; D001564:Benzo(a)pyrene / Q000032:analysis; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry; D003367:Cotinine / Q000097:blood; D006632:Histamine / Q000032:analysis; D010196:Pancreatic Elastase / Q000097:blood; D011817:Rabbits; D012907:Smoking / Q000009:adverse effects; D013929:Thromboxane B2 / Q000097:blood; D014028:Tobacco Smoke Pollution / Q000009:adverse effects* / Q000032:analysis
D014028:Tobacco Smoke Pollution; D001564:Benzo(a)pyrene; D013929:Thromboxane B2; D006632:Histamine; D010196:Pancreatic Elastase; D003367:Cotinine