Enhanced recovery of learned alternation in ganglioside-treated rats after unilateral entorhinal lesions.
The present study demonstrates that an abbreviated regimen of ganglioside treatments attenuates the behavioral impairments produced by unilateral lesions of the entorhinal cortex. Ganglioside treatments not only accelerate recovery of learned alternation on a Y-maze, but also reduce total errors and perseverative errors.
Ramirez
J J
JJ
Department of Psychology, Davidson College, NC 28036.
Fass-Holmes
B
B
Karpiak
S E
SE
Harshbarger
R
R
Zengel
D
D
Wright
P
P
Valbuena
M
M
D000818:Animals; D001931:Brain Mapping; D004193:Discrimination Learning / Q000187:drug effects*; D005732:Gangliosides / Q000494:pharmacology*; D008032:Limbic System / Q000187:drug effects*; D008297:Male; D011939:Mental Recall / Q000187:drug effects*; D009416:Nerve Regeneration / Q000187:drug effects*; D009949:Orientation / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains; D012153:Retention, Psychology / Q000187:drug effects
D005732:Gangliosides