title: Interactions between chromosomal omnipotent suppressors and extrachromosomal effectors in Saccharomyces cerevisiae.
abstract: Chromosomal omnipotent suppressor mutations recovered in psi+ strains of Saccharomyces cerevisiae were brought into psi- cytoplasm. SUP46, SUP138 and SUP139 acted as dominant omnipotent suppressors in the psi- cytoplasm though their suppressor activity was substantially reduced. SUP46 and SUP138 conferred recessive thermosensitivity and antibiotic sensitivity in psi- cytoplasm as in psi+ cytoplasm. On the other hand, sup111 through sup115, which acted as recessive omnipotent suppressors in the psi+ cytoplasm, manifested no, or very low, suppressor activity in the psi- cytoplasm. They, however, still enhanced the efficiency of the SUP29 tRNA suppressor in psi- cytoplasm. A multicopy plasmid carrying the wild-type SUP35 gene enhanced the efficiency of sup111 in psi- cytoplasm.
authors.affiliation: Laboratory of Environmental Hygiene Chemistry, Faculty of Pharmaceutical Sciences, Okayama University, Japan.
authors.forename: B
authors.initials: B
authors.lastname: Ono
authors.forename: Y O
authors.initials: YO
authors.lastname: Chernoff
authors.forename: Y
authors.initials: Y
authors.lastname: Ishino-Arao
authors.forename: N
authors.initials: N
authors.lastname: Yamagishi
authors.forename: S
authors.initials: S
authors.lastname: Shinoda
authors.forename: S G
authors.initials: SG
authors.lastname: Inge-Vechtomov
mesh_terms: D005111:Extrachromosomal Inheritance; D005799:Genes, Dominant; D005800:Genes, Fungal; D005808:Genes, Recessive; D016153:Genes, Suppressor; D005816:Genetic Complementation Test; D010957:Plasmids; D014176:Protein Biosynthesis; D012331:RNA, Fungal / Q000235:genetics; D012343:RNA, Transfer / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000235:genetics*
chemical_list: D012331:RNA, Fungal; D012343:RNA, Transfer