title: Modelling and numerical optimization of corneal rotation.
abstract: Rotational ipsilateral penetrating autokeratoplasty can be performed for patients whose vision is impaired by corneal opacities overlying the pupil and where an adequate area of clear peripheral cornea is present. A method is presented for determining the maximum clear central corneal area that can be obtained by rotational autokeratoplasty and the most appropriate trephine size and placement. The mathematical modelling consists of estimating the shape of the opacity perimeter using nonlinear constrained optimization.
authors.affiliation: INSERM U. 86, Université Paris VI, Hôtel-Dieu, Paris, France.
authors.forename: I
authors.initials: I
authors.lastname: Karpouzas
authors.forename: Y
authors.initials: Y
authors.lastname: Pouliquen
mesh_terms: D003315:Cornea / Q000601:surgery*; D003318:Corneal Opacity / Q000473:pathology / Q000601:surgery*; D006801:Humans; D015948:Keratoplasty, Penetrating / Q000379:methods*; D008962:Models, Theoretical