The 18-kilodalton antigen secreted by Aspergillus fumigatus.
One of the major antigens secreted in vitro by Aspergillus fumigatus is an 18-kDa basic protein which has been purified by cation-exchange chromatography. It is recognized by sera from aspergilloma patients. It is also the major circulating antigen found in urine of patients with invasive aspergillosis. Our results indicated that this antigen has potential for the diagnosis of both aspergilloma and invasive aspergillosis.
Latgé
J P
JP
Unité de Mycologie, Institut Pasteur, Paris, France.
Moutaouakil
M
M
Debeaupuis
J P
JP
Bouchara
J P
JP
Haynes
K
K
Prévost
M C
MC
D000908:Antibodies, Fungal / Q000276:immunology; D000946:Antigens, Fungal / Q000276:immunology / Q000302:isolation & purification / Q000378:metabolism* / Q000652:urine; D001228:Aspergillosis / Q000276:immunology; D001232:Aspergillus fumigatus / Q000276:immunology*; D002177:Candidiasis / Q000276:immunology; D011232:Chemical Precipitation; D002851:Chromatography, High Pressure Liquid; D004797:Enzyme-Linked Immunosorbent Assay; D000431:Ethanol; D006801:Humans; D015151:Immunoblotting; D012995:Solubility; D014867:Water / Q000737:chemistry
D000908:Antibodies, Fungal; D000946:Antigens, Fungal; D014867:Water; D000431:Ethanol