Conformationally restrained aminoalkylindoles: potent, stereoselective ligands at the cannabinoid binding site.
Estep
K G
KG
Department of Medicinal Chemistry, Sterling Research Group, Rensselaer, NY 12144.
D'Ambra
T E
TE
Olefirowicz
E M
EM
Bell
M R
MR
Eissenstat
M A
MA
Haycock
D A
DA
Ward
S J
SJ
D000700:Analgesics / Q000494:pharmacology; D007211:Indoles / Q000494:pharmacology; D008024:Ligands; D008968:Molecular Conformation; D043882:Receptors, Cannabinoid; D011955:Receptors, Drug / Q000187:drug effects*
D000700:Analgesics; D007211:Indoles; D008024:Ligands; D043882:Receptors, Cannabinoid; D011955:Receptors, Drug; C062767:pravadoline