[Correlation between activity of tissue basophils and leukocytes and permeability of mesenteric venules of rats in experimental peritonitis].
Calculation of adhered leukocytes, degranulated mast cells and leaked mesentery venules have been prepared in 1, 2, 4 and 8 hours after induction of inflammation. Number of adhered to the venular walls leukocytes enhanced with constant speed for the first 4 hours. The speed of the appearance of new mast cells with the signs of the degranulation in the period was raised. Alteration of the number (share) of leak vessels had parallel dynamic. This data show that in this model of inflammation the main role in disturbances of the permeability is played by products of the degranulation of must cells. In 4 hours and more predominant significance in genesis of disturbances of transport function of vessels wall begin to acquire metabolites of activated leukocytes--free radicals of the oxygen. Apparently this substances played an important role in the mechanism of releasing of the thrombosis.
Zaĭtsev
K T
KT
D000818:Animals; D002199:Capillary Permeability; D007962:Leukocytes / Q000502:physiology*; D008407:Mast Cells / Q000502:physiology*; D008643:Mesentery / Q000098:blood supply*; D010538:Peritonitis / Q000473:pathology* / Q000503:physiopathology; D051381:Rats; D013997:Time Factors; D014699:Venules / Q000503:physiopathology*
Sootnoshenie aktivnosti tkanevykh bazofilov, leĭkotsitov i pronitsaemosti venul bryzheĭki krysy pri modelirovanii peritonita.