title: Two cases of nickel dermatitis showing vitiligo-like depigmentations.
abstract: The authors reviewed two patients showing "vitiligo-like depigmentations" where the skin had been in close contact with a metal spectacle frame made of nickel alloy. In spite of the hypersensitivity to nickel in both patients, they showed clinical and histologic findings indicate that the formation of "vitiligo-like depigmentation" does not result from posinflammatory hypopigmentation but from chemical hypomelanosis. We could not explain the underlying mechanisms; however, the speculation that the "vitiligo-like depigmentation" may come from the direct effect of the nickel itself, prompted us to report these cases.
authors.affiliation: Department of Microbiology, Ajou University College of Medicine, Suwon, Korea.
authors.forename: H I
authors.initials: HI
authors.lastname: Kim
authors.forename: D H
authors.initials: DH
authors.lastname: Kim
authors.forename: M S
authors.initials: MS
authors.lastname: Yoon
authors.forename: H J
authors.initials: HJ
authors.lastname: Kim
authors.forename: S
authors.initials: S
authors.lastname: Lee
mesh_terms: D000328:Adult; D003877:Dermatitis, Contact / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009532:Nickel / Q000009:adverse effects*; D014820:Vitiligo / Q000139:chemically induced*
chemical_list: D009532:Nickel