title: [Changes in leucocytic estrogen receptor levels in patients with gynecomastia].
abstract: The number of estrogen receptor (ER) in human peripheral leucocytes in 13 men with gynecomastia were measured by radioligand binding method. The results were compared with those of 13 sex-and age-matched healthy subjects. It was found that the number of ER in leucocytes was significantly increased in gynecomastia (Rs of leucocytes were 1054 +/- 254 sites/cell). It suggested that increase of ER levels play an important role in the pathogenesis of gynecomastia.
authors.affiliation: Department of Endocrinology, Changhai Hospital, Second Military Medical College, Shanghai.
authors.forename: D J
authors.initials: DJ
authors.lastname: Zhou
authors.forename: J Q
authors.initials: JQ
authors.lastname: Zhang
authors.forename: D B
authors.initials: DB
authors.lastname: Qiao
mesh_terms: D000328:Adult; D000368:Aged; D004958:Estradiol / Q000097:blood; D006177:Gynecomastia / Q000097:blood*; D006801:Humans; D007962:Leukocytes / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011869:Radioligand Assay; D011960:Receptors, Estrogen / Q000097:blood*; D013739:Testosterone / Q000097:blood
chemical_list: D011960:Receptors, Estrogen; D013739:Testosterone; D004958:Estradiol