title: [Anesthesia for thalamic stimulations: value of flumazenil].
abstract: Five cases are reported of peroperative awakening in order to obtain patient cooperation during stereotaxic procedures. General anaesthesia was induced with 0.25 mg.kg-1 midazolam, 1.5 to 2 micrograms.kg-1 fentanyl, and 0.1 mg.kg-1 vecuronium. Maintenance was obtained with isoflurane, nitrous oxide, and small doses of fentanyl. Isoflurane inhalation was discontinued 30 to 40 min before the time of awakening required by surgery. Once expiratory isoflurane concentration reached a level less than or equal to 0.1%, nitrous oxide administration was stopped, and 0.5 mg flumazenil administered. After surgical checking, on the fully awake patient of the efficiency of thalamic stimulation and the lack of any motor deficit, anaesthesia was deepened again, with either isoflurane or a non benzodiazepine intravenous agent. All five patients recovered rapidly and calmly.
authors.affiliation: Département d'Anesthésie-Réanimation, Hôpital Henri-Mondor, Créteil.
authors.forename: G
authors.initials: G
authors.lastname: Orliaguet
authors.forename: J P
authors.initials: JP
authors.lastname: Nguyen
authors.forename: K
authors.initials: K
authors.lastname: Abay
authors.forename: E
authors.initials: E
authors.lastname: Berberich
authors.forename: E
authors.initials: E
authors.lastname: Melon
authors.forename: P
authors.initials: P
authors.lastname: Duvaldestin
mesh_terms: D000328:Adult; D000368:Aged; D000768:Anesthesia, General / Q000379:methods*; D004558:Electric Stimulation; D005442:Flumazenil / Q000494:pharmacology*; D006801:Humans; D007432:Intraoperative Period; D008297:Male; D008874:Midazolam / Q000037:antagonists & inhibitors*; D008875:Middle Aged; D009437:Neuralgia / Q000601:surgery; D010300:Parkinson Disease / Q000601:surgery; D013238:Stereotaxic Techniques; D013788:Thalamus; D014202:Tremor / Q000601:surgery
chemical_list: D005442:Flumazenil; D008874:Midazolam
vernacular_title: Anesthésie pour stimulations thalamiques: intérêt du flumazénil.