title: [Determination of the level of heparinization necessary to provide cascade filtration exchange plasmapheresis in patients with generalized suppurative peritonitis].
abstract: Activated clotting time was determined during cascade filtration exchange plasmapheresis (CFEP) in 24 patients with generalized suppurative peritonitis. A modified method of activated clotting time determination, using a home-made infusorial earth substitute of the type of "Kieselguhr" was used. A gradual decrease in activated clotting time during CFEP has been observed, which required additional heparin administration. By the end of the procedure, when the removed plasma volume reached 1500 ml, activated clotting time values returned practically to baseline.
authors.forename: L A
authors.initials: LA
authors.lastname: Ender
authors.forename: A V
authors.initials: AV
authors.lastname: Vatazin
authors.forename: L I
authors.initials: LI
authors.lastname: Iunovidova
mesh_terms: D000328:Adult; D001777:Blood Coagulation / Q000187:drug effects*; D005260:Female; D006493:Heparin / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D010538:Peritonitis / Q000503:physiopathology*; D010956:Plasmapheresis / Q000379:methods*; D013997:Time Factors
chemical_list: D006493:Heparin
vernacular_title: Opredelenie neobkhodimogo urovnia geparinizatsii pri provedenii kaskadnogo fil'tratsionnogo obmennogo plazmafereza u bol'nykh razlitym gnoĭnym peritonitom.