Cellular interactions in asthma.
Immediate phase of asthma is induced by mast cells. Late phase asthmatic response is related to other cells such as, macrophages, lymphocytes, eosinophils, and could pass to chronicity and is usually associated with bronchial hyperreactivity. Pathological or functional studies of the different cells involved, could be done in peripheral blood, broncho-alveolar lavage, bronchial biopsies or nasal lavages.
Palma-Carlos
A G
AG
Inst. Immunologia Clinica universitária medicina I, CHIUL-INIC, Fac. Mecidina, Lisboa, Portugal.
Palma-Carlos
M L
ML
Santos
M C
MC
Simoes
M H
MH
de Sousa
J R
JR
D001249:Asthma / Q000473:pathology*; D001792:Blood Platelets / Q000187:drug effects / Q000473:pathology; D006801:Humans; D007249:Inflammation; D008214:Lymphocytes / Q000473:pathology; D008264:Macrophages / Q000187:drug effects / Q000473:pathology; D008407:Mast Cells / Q000473:pathology