title: Effect of a live reovirus vaccine on reproductive performance of broiler breeder hens and development of viral tenosynovitis in progeny.
abstract: A live commercial reovirus vaccine, Enterovax, was administered to adult broiler breeder hens via the drinking water to determine its efficacy in stimulation of circulating antibody. This vaccine was compared with a commercial inactivated reovirus vaccine. Only the inactivated product resulted in increased antibody as measured by a commercial enzyme-linked immunosorbent assay. However, the live reovirus vaccine caused diarrhea in the hens and decreased eggshell quality, fertility, and hatchability. In addition, the live vaccine virus was vertically transmitted from hens to their progeny, resulting in increased embryonic mortality and viral tenosynovitis.
authors.affiliation: Poultry Science Department, Auburn University, Alabama 36849-5416.
authors.forename: J J
authors.initials: JJ
authors.lastname: Giambrone
authors.forename: T L
authors.initials: TL
authors.lastname: Hathcock
authors.forename: S B
authors.initials: SB
authors.lastname: Lockaby
mesh_terms: D000284:Administration, Oral; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002645:Chickens; D003967:Diarrhea / Q000139:chemically induced / Q000662:veterinary; D004326:Drinking; D004531:Eggs / Q000592:standards; D005260:Female; D005298:Fertility / Q000187:drug effects; D007117:Immunization, Secondary / Q000662:veterinary; D008297:Male; D010058:Oviposition / Q000187:drug effects; D011201:Poultry Diseases / Q000209:etiology*; D012087:Reoviridae / Q000276:immunology*; D013717:Tenosynovitis / Q000209:etiology / Q000662:veterinary*; D014611:Vaccination / Q000662:veterinary; D015164:Vaccines, Inactivated / Q000276:immunology; D014765:Viral Vaccines / Q000008:administration & dosage / Q000009:adverse effects* / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D015164:Vaccines, Inactivated; D014765:Viral Vaccines