Sequence of the Candida albicans gene encoding the secretory aspartate proteinase.
The gene encoding the Candida albicans aspartate proteinase that is secreted by cells grown in protein-containing media was cloned from a C. albicans genomic bank. The base sequence of the insert shows a 1173 bp open-reading frame and indicates an amino acid sequence typical of aspartate proteinases, with amino acid sequence homology to other enzymes of this class and a putative signal peptide consisting of 50 amino acids upstream of the active enzyme.
Hube
B
B
Hygiene-Institut der Universität, Göttingen, Germany.
Turver
C J
CJ
Odds
F C
FC
Eiffert
H
H
Boulnois
G J
GJ
Köchel
H
H
Rüchel
R
R
D000595:Amino Acid Sequence; D016282:Aspartic Acid Endopeptidases / Q000235:genetics*; D001483:Base Sequence; D002176:Candida albicans / Q000201:enzymology / Q000235:genetics*; D003001:Cloning, Molecular; D003470:Culture Media; D004271:DNA, Fungal / Q000737:chemistry*; D008969:Molecular Sequence Data; D015345:Oligonucleotide Probes; D016366:Open Reading Frames; D016133:Polymerase Chain Reaction; D021382:Protein Sorting Signals / Q000235:genetics
D003470:Culture Media; D004271:DNA, Fungal; D015345:Oligonucleotide Probes; D021382:Protein Sorting Signals; D016282:Aspartic Acid Endopeptidases