title: Changes in testicular lactate dehydrogenases of the rat (Rattus norvegicus) during growth and development.
abstract: 1. We have quantified lactate dehydrogenase (LDH) A, B and C enzyme levels during the first twelve weeks of life in rat testes. 2. Proteins were electrophoresed under non-denaturing conditions, isoenzymes identified by activity staining and quantified by densitometry scanning. 3. LDH A declined 2-3-fold during testes growth, changing from the most to the least abundant isoenzyme form. LDH B remained fairly constant, and LDH C increased from undetectable levels at birth to become the most abundant of the three polypeptides from week 3 onwards.
authors.affiliation: Department of Biochemistry, University of Sussex, Falmer, Brighton, UK.
authors.forename: A F
authors.initials: AF
authors.lastname: Skidmore
authors.forename: T J
authors.initials: TJ
authors.lastname: Beebee
mesh_terms: D000375:Aging / Q000378:metabolism; D000818:Animals; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D046911:Macromolecular Substances; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013737:Testis / Q000201:enzymology / Q000254:growth & development*
chemical_list: D007527:Isoenzymes; D046911:Macromolecular Substances; D007770:L-Lactate Dehydrogenase