title: Klion in the prevention of early complications following appendectomy.
abstract: The authors observations with prophylactic administration of metronidazole manufactured by the Gedeon Richter Company, Hungary (trade mark Klion) in children with phlegmonous appendicitis are reported. The drug was administered in three doses to 51 children. Results of bacteriology could be assessed in 42 children. The results of prophylactic administration of Klion in phlegmonous appendicitis were excellent. In our group there were no inflammatory wounds and/or intraperitoneal complications. For comparison, in a cohort of 1.008 children with phlegmonous appendicitis, without prophylaxis the rate of inflammatory complications was 3.62%. Klion has minimal side effects and is well tolerated and seems to be a superb drug for prophylaxis.
authors.affiliation: Department of Paediatric Surgery, Thomayer's Teaching Hospital, Prague.
authors.forename: H
authors.initials: H
authors.lastname: Hájková
authors.forename: M
authors.initials: M
authors.lastname: Prichlik
authors.forename: M
authors.initials: M
authors.lastname: Bártová
authors.forename: L
authors.initials: L
authors.lastname: Brezinová
authors.forename: M
authors.initials: M
authors.lastname: Hatala
mesh_terms: D001062:Appendectomy / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage*; D013530:Surgical Wound Infection / Q000517:prevention & control*
chemical_list: D008795:Metronidazole