title: Diagnostic classification of antineutrophil cytoplasmic autoantibody-associated vasculitides.
abstract: Antineutrophil cytoplasmic autoantibodies (ANCA) are in the circulation of patients with a variety of clinically and pathologically distinctive forms of necrotizing vasculitis. Some patients have classic manifestations of well-recognized clinicopathologic syndromes, such as Wegener's granulomatosis, microscopic polyarteritis nodosa, and Churg-Strauss syndrome, but many patients are difficult to assign to a diagnostic category. The Ad Hoc Nomenclature Committee of The Third International Workshop on ANCA is attempting to identify a working classification system for ANCA-associated vasculitides. This system takes into account the many shared clinical and pathologic features, and relies on prerequisite positive and negative findings for diagnostic categorization.
authors.affiliation: Department of Pathology, School of Medicine, University of North Carolina, Chapel Hill 27599.
authors.forename: J C
authors.initials: JC
authors.lastname: Jennette
authors.forename: R J
authors.initials: RJ
authors.lastname: Falk
mesh_terms: D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies / Q000145:classification* / Q000302:isolation & purification; D001327:Autoimmune Diseases / Q000145:classification; D006801:Humans; D009504:Neutrophils / Q000276:immunology*; D009626:Terminology as Topic; D014657:Vasculitis / Q000145:classification* / Q000175:diagnosis / Q000276:immunology
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies