title: [The effect of ecdysterone on experimental arrhythmias and changes in the hemodynamics and myocardial contractility induced by coronary artery occlusion].
abstract: In acute animal experiments it was shown that phytoecdizon ecdisteron (ecdisten) in some animals eliminates arrhythmia caused by the ligation of the descending branch of the left coronary artery and prevents the development of fibrillation and also corrects the hemodynamic parameters and the structure of the heart contractility, prevents the development of arrhythmias induced by aconitine and calcium chloride. The mechanism of the antiarrhythmic action is related to the membrane stabilizing effect and the improvement of the hemodynamic parameters and the heart contractility is due to an increase of the adaptative possibilities of the myocardium.
authors.forename: A G
authors.initials: AG
authors.lastname: Kurmukov
authors.forename: O A
authors.initials: OA
authors.lastname: Ermishina
mesh_terms: D000157:Aconitine; D000818:Animals; D000889:Anti-Arrhythmia Agents; D001145:Arrhythmias, Cardiac / Q000139:chemically induced / Q000188:drug therapy* / Q000503:physiopathology; D002122:Calcium Chloride; D002415:Cats; D003327:Coronary Disease / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D004441:Ecdysterone / Q000494:pharmacology / Q000627:therapeutic use*; D006439:Hemodynamics / Q000187:drug effects; D009200:Myocardial Contraction / Q000187:drug effects* / Q000502:physiology; D051381:Rats
chemical_list: D000889:Anti-Arrhythmia Agents; D004441:Ecdysterone; D002122:Calcium Chloride; D000157:Aconitine
vernacular_title: Vliianie ékdisterona na éksperimental'nye aritmii, izmeneniia gemodinamiki i sokratimosti miokarda, vyzvannye okkliuzieĭ koronarnoĭ arterii.