title: Thyrotropin and prolactin responses to ECT in schizophrenia and depression.
abstract: Thyroid stimulating hormone (TSH) and prolactin (PRL) plasma levels were studied during electroconvulsive therapy (ECT) in five schizophrenic patients in a simulated ECT (SECT) controlled experimental design. The data were compared to those obtained from a group of 10 depressed patients treated with ECT. In the schizophrenic group, both PRL and TSH increased significantly during ECT compared to SECT, as they did in the depressive group during ECT. Thus, the hormonal TSH and PRL profile during ECT is similar in schizophrenia and depression. It is concluded that the changes in TSH and PRL induced by ECT are specifically linked to the current or the seizure, and are not related to the type of psychopathology.
authors.affiliation: Athens University Medical School Psychiatric Clinic, Greece.
authors.forename: Y
authors.initials: Y
authors.lastname: Papakostas
authors.forename: M
authors.initials: M
authors.lastname: Markianos
authors.forename: G
authors.initials: G
authors.lastname: Papadimitriou
authors.forename: L
authors.initials: L
authors.lastname: Lykouras
authors.forename: C
authors.initials: C
authors.lastname: Stefanis
mesh_terms: D000328:Adult; D001143:Arousal / Q000502:physiology; D003866:Depressive Disorder / Q000097:blood / Q000523:psychology / Q000628:therapy*; D004565:Electroconvulsive Therapy; D005260:Female; D006801:Humans; D011388:Prolactin / Q000097:blood*; D012559:Schizophrenia / Q000097:blood / Q000628:therapy*; D012565:Schizophrenic Psychology; D013972:Thyrotropin / Q000097:blood*
chemical_list: D011388:Prolactin; D013972:Thyrotropin