[Aminoglycoside-inactivating enzymes in strains of Salmonella and genes encoding them].
Aminoglycoside resistance patterns of 56 strains isolated from man, cattle and environment were determined. 34 out of 42 gentamicin-resistant strains were shown to produce AAC(3)-II and 7 strains produced ANT(2"). All the 48 kanamycin resistant strains produced APH(3')-I. Spot hybridization of the 42 gentamicin resistant strains with the inner fragment of the aacC2 gene revealed positive signals for all the strains. Hybridization of the 48 kanamycin-resistant strains with the aphA1 gene probe provided positive results in all the strains. The AAC(3)-IV encoding gene was not detected by DNA-DNA hybridization in the strains studied.
Vakulenko
S B
SB
Kolganov
A N
AN
Krotova
L A
LA
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000378:metabolism*; D004269:DNA, Bacterial / Q000235:genetics; D004352:Drug Resistance, Microbial / Q000235:genetics; D007613:Kanamycin Resistance / Q000235:genetics; D009693:Nucleic Acid Hybridization; D012475:Salmonella / Q000201:enzymology* / Q000235:genetics
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial
Aminoglikozidinaktiviruiushchie fermenty shtammov sal'monell i kodiruiushchie ikh geny.