[Correction with T-activin of secondary immunodeficiency in inflammatory diseases of female internal genital organs].
A clinicoimmunological examination was performed in 70 patients with acute inflammatory disease of internal genitalia. All the patients received a multimodality anti-inflammatory therapy. They were divided into 2 groups: 1) 30 patients taking ++T-activin as an adjuvant and 2) 40 patients untreated with it. T and B lymphocytes were measured by current cytofluorometry+ by means of monoclonal antibodies and the rosette-forming method. A subpopulation analysis of the T-cell immune system revealed lower T-helper count and decreased immunoregulatory index. ++T-activin used in the multimodality therapy for acute inflammatory diseases of internal genitalia improved the qualitative parameters of regulatory T-cell subpopulations, returned T and B lymphocytes to normal levels and elevated IgG concentrations.
Pogodin
O K
OK
Samorodinova
L A
LA
Matveeva
N K
NK
Sukhikh
G T
GT
D000208:Acute Disease; D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007958:Leukocyte Count / Q000187:drug effects; D008231:Lymphopenia / Q000188:drug therapy* / Q000209:etiology; D000292:Pelvic Inflammatory Disease / Q000188:drug therapy / Q000276:immunology*; D010455:Peptides / Q000627:therapeutic use*; D013601:T-Lymphocytes / Q000276:immunology* / Q000473:pathology; D013949:Thymus Extracts / Q000627:therapeutic use*
D000276:Adjuvants, Immunologic; D010455:Peptides; D013949:Thymus Extracts; C036191:T-activin
Korrektsiia taktivinom vtorichnogo immunodefitsita pri vospalitel'- nykh zabolevaniiakh vnutrennikh genitaliĭ zhenshchin.