[Post-stress disorders of resistance of mice to recurrent infection by homologous influenza virus].
A decrease in the mouse resistance to reinfection by influenza virus under the effect of immobilization stress was depicted. Violation in the formation of a long-term resistance to a repeated disease ran in the presence of the high levels of circulating anti-influenza antibodies and not ++always correlated with a post-stress impairment of the formation of antigen-reactive clones of cells in the spleen of primarily infected mice. Prophylactic administration of ionol which prevented a post-stress aggravation of the primary influenza infection failed to produce a favourable effect on the immunity in case of reinfection.
Kramskaia
T A
TA
Chetverikova
L K
LK
Frolova
B A
BA
Poliak
R Ia
RIa
D000818:Animals; D004195:Disease Models, Animal; D007108:Immune Tolerance / Q000276:immunology*; D009980:Influenza A virus / Q000276:immunology / Q000472:pathogenicity*; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009976:Orthomyxoviridae Infections / Q000209:etiology / Q000276:immunology*; D012008:Recurrence; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000150:complications / Q000276:immunology*
Poststressornoe narushenie ustoĭchivosti mysheĭ k povtornomu zarazheniiu gomologichnym virusom grippa.