title: Osteoinductive property of fluoride impregnated decalcified allogeneic bone matrix.
abstract: Present study was carried out in order to explore the ability of a bone graft-decalcified as well as fluoridated to form new bone when put in the rectus abdominis muscle of rabbit. A total of 66 implants placed inside the pouches created in rectus abdominis muscle of rabbits were followed for 2 to 20 weeks. Radiologically decal implants formed bone in 74% cases and fluoridated implants in 68%; whereas histologically 86% of decalcified and 80% of fluoride impregnated decal bone matrix showed evidence of bone induction. It is concluded that fluoride impregnation does not enhance the osteogenic potential of a decal bone matrix.
authors.affiliation: Department of Orthopaedics, Banaras Hindu University, Varanasi, India.
authors.forename: S K
authors.initials: SK
authors.lastname: Saraf
authors.forename: S M
authors.initials: SM
authors.lastname: Tuli
mesh_terms: D000005:Abdomen / Q000601:surgery; D000818:Animals; D016025:Bone Transplantation; D005459:Fluorides / Q000494:pharmacology*; D010012:Osteogenesis / Q000187:drug effects*; D011817:Rabbits; D016042:Transplantation, Heterotopic
chemical_list: D005459:Fluorides