title: Effect of the mineralizing agent on the permanent teeth.
abstract: In a two-year pragmatic clinical trial, the effect of the mineralizing agent was evaluated on permanent teeth of the first eruption group among Finnish children (7-years old at the beginning of the study) with a low prevalence of DFS. In the test group (n = 123, biweekly mouthrinsing with a 2% solution of mineralizing agent and 0.2% NaF solution) the percentage reduction in increment of both EFDS and DFS was high, whereas in the control group (n = 123, biweekly mouthrinsing with placebo and 0.2% NaF solutions) the incidence for symptoms of caries disease did not differ from that normally found in this age cohort. Positive clinical effect of tested solution was age-related and was associated with remineralization of old and inhibition of occurrence of new EFD lesions.
authors.affiliation: Department of Oral Pathology, Oral Roentgenology and Forensic Dentistry, Institute of Dentistry, University of Kuopio, Finland.
authors.forename: S
authors.initials: S
authors.lastname: Kolmakow
authors.forename: E
authors.initials: E
authors.lastname: Honkala
authors.forename: E V
authors.initials: EV
authors.lastname: Borovsky
authors.forename: E M
authors.initials: EM
authors.lastname: Kuzmina
authors.forename: S A
authors.initials: SA
authors.lastname: Vasina
mesh_terms: D002327:Cariostatic Agents; D002648:Child; D003731:Dental Caries / Q000517:prevention & control*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008903:Minerals; D009067:Mouthwashes; D014089:Tooth Remineralization
chemical_list: D002327:Cariostatic Agents; D008903:Minerals; D009067:Mouthwashes