Effect of dimethoate and fenvalerate on conditioned avoidance and passive avoidance responses.
Dimethoate at 24.75 and 49.5 mg/kg (i.e., 1/10 and 1/5th LD50 respectively) impaired the learning process and retrieval of memory in rats while it did not affect permanent memory. Fenvalerate / 10.12 and 20 mg/kg (i.e., 1/20 and 1/10th LD50 respectively) had no effect on learning process, retrieval of memory and permanent memory traces.
Reddy
B N
BN
Department of Pharmacology and Toxicology, College of Veterinary Science, Rajendranagar, Hyderabad, India.
Reddy
K S
KS
Janardhan
A
A
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects*; D004117:Dimethoate / Q000633:toxicity*; D007306:Insecticides / Q000633:toxicity*; D008297:Male; D009570:Nitriles; D011722:Pyrethrins / Q000633:toxicity*; D051381:Rats; D011919:Rats, Inbred Strains
D007306:Insecticides; D009570:Nitriles; D011722:Pyrethrins; D004117:Dimethoate; C017690:fenvalerate