Hydrolysed microspheres from cross-linked polymethyl methacrylate (Hydrogel). A new embolic material for interventional neuroradiology.
Highly hydrophilic, perfectly smooth and spherical microspheres have been synthetized. These non-biodegradable microspheres absorb water in varying degrees and can be injected easily through microcatheters due to their slippery and compressible characteristics. The material was successfully used for embolization of 4 vascular intracranial tumours and 2 spinal vascular lesions in the cervical region, by superselective delivery. Histopathology confirmed absolute inertness of the microspheres.
Rao
V R
VR
Department of radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.
Ravimandalam
K
K
Jayakrishnan
A
A
Thanoo
B C
BC
Radhakrishnan
V V
VV
Gupta
A K
AK
Kumar
S
S
Joseph
S
S
Unni
M
M
Rao
A S
AS
D000328:Adult; D015901:Angiography, Digital Subtraction; D001165:Arteriovenous Malformations / Q000628:therapy; D001932:Brain Neoplasms / Q000628:therapy; D002404:Catheterization; D002648:Child; D004621:Embolization, Therapeutic / Q000295:instrumentation* / Q000379:methods; D005260:Female; D006801:Humans; D006868:Hydrolysis; D008297:Male; D008579:Meningioma / Q000098:blood supply / Q000628:therapy; D008768:Methylmethacrylates / Q000138:chemical synthesis / Q000737:chemistry; D008863:Microspheres; D008875:Middle Aged; D015642:Radiology, Interventional; D013131:Spine / Q000098:blood supply; D014711:Vertebral Artery / Q000002:abnormalities
D008768:Methylmethacrylates