[Quantitative dermatoglyphic markers in fra-X-syndrome].
Quantitative dermatoglyphic characters of fingers and palms of 61 male patients with fra-X-syndrome and 20 female heterozygote carriers were analysed and compared with the data from 84 male and 90 female normal individuals. Univariate and multivariate analysis of the data led to the following conclusions: 1. The fra-X-syndrome patients show higher ridge count and higher MLI value (increased transversality of the main lines), and lower a-b ridge counts than the controls. In addition to this, differences are observed also for the diversity and asymmetry measures. 2. Discriminant analysis as applied to the sexes separately, showed that 75% of males can be correctly classified in their group. However, the percent of correctly classified females is lower than the males; it is 70% (fra-X female) ad 64.4% (control female). 3. D2-matrix and the comparison of TFR C values support the hypothesis of X-chromosomal doses effect on the dermatoglyphics.
Rodewald
A
A
Institut für Humanbiologie, Universität Hamburg.
Chopra
V P
VP
D000328:Adult; D003878:Dermatoglyphics / Q000145:classification*; D005260:Female; D005600:Fragile X Syndrome / Q000175:diagnosis / Q000235:genetics*; D006580:Genetic Carrier Screening; D005819:Genetic Markers / Q000235:genetics*; D014644:Genetic Variation / Q000235:genetics; D006801:Humans; D008297:Male; D008957:Models, Genetic; D010641:Phenotype
D005819:Genetic Markers
Untersuchungen quantitativer Hautleistenmerkmale beim fra-X-Syndrom.