title: Three-dimensional numerical analysis of pulsatile flow and wall shear stress in the carotid artery bifurcation.
abstract: To analyse the pulsatile flow field and the mechanical stresses in a three-dimensional carotid artery bifurcation model, computer simulation is applied. The approximation of the Navier-Stokes equations uses a pressure correction finite element method. Numerical results are presented for axial and secondary flow velocity and wall shear stresses with special emphasis on the fluid dynamics in the carotid sinus. This region is of major interest because it is affected preferentially by lesions. Detailed local flow studies as carried out here should lead to a further insight into the mechanisms of atherogenesis. The flow conditions used in the study were chosen according to Ku et al. (Arteriosclerosis 5, 293-302, 1985). The results of this numerical analysis agree in the essential features with their experimental results.
authors.affiliation: Institute of Mathematics, Technical University Graz, Austria.
authors.forename: K
authors.initials: K
authors.lastname: Perktold
authors.forename: M
authors.initials: M
authors.lastname: Resch
authors.forename: R O
authors.initials: RO
authors.lastname: Peter
mesh_terms: D001783:Blood Flow Velocity; D001794:Blood Pressure / Q000502:physiology; D002339:Carotid Arteries / Q000502:physiology*; D003198:Computer Simulation; D006801:Humans; D008955:Models, Cardiovascular; D011673:Pulsatile Flow / Q000502:physiology; D012212:Rheology; D013314:Stress, Mechanical