title: Evaluation of liver function tests in screening for intra-abdominal injuries.
abstract: OBJECTIVE
  To determine the utility of serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT) in predicting intra-abdominal injury in blunt trauma patients.
  
  
  METHODS
  Descriptive review of 309 blunt trauma admissions during study period.
  
  
  METHODS
  A 1,000-bed Level I trauma center in a major metropolitan area.
  
  
  METHODS
  Consecutive adult blunt trauma admissions to the trauma service.
  
  
  METHODS
  Serum levels of study enzymes were measured at initial evaluation and subsequent hospitalization. Results of all intra-abdominal evaluations were recorded.
  
  
  RESULTS
  Significantly greater numbers of patients with SGOT and/or SGPT elevated to more than 130 IU/L had associated intra-abdominal injuries as compared with patients with enzyme elevations of less than 130 IU/L (52% versus 8%). All 18 patients with liver injuries had one or both enzymes elevated to more than 130 IU/L. Higher enzyme levels were more frequently associated with liver injury.
  
  
  CONCLUSIONS
  Elevation of serum levels of the study enzymes is a marker for intra-abdominal injury. Levels in excess of 130 IU/L are relative indicators of abdominal computed tomography scan. Levels of less than 130 IU/L are unlikely to be associated with liver injury.
authors.affiliation: Department of Trauma, Nassau County Medical Center, East Meadow, New York 11554.
authors.forename: P
authors.initials: P
authors.lastname: Sahdev
authors.forename: R R
authors.initials: RR
authors.lastname: Garramone
authors.forename: R J
authors.initials: RJ
authors.lastname: Schwartz
authors.forename: S R
authors.initials: SR
authors.lastname: Steelman
authors.forename: L M
authors.initials: LM
authors.lastname: Jacobs
mesh_terms: D000007:Abdominal Injuries / Q000097:blood / Q000175:diagnosis*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000410:Alanine Transaminase / Q000097:blood*; D001219:Aspartate Aminotransferases / Q000097:blood*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008099:Liver / Q000293:injuries; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D015599:Trauma Severity Indices; D014949:Wounds, Nonpenetrating / Q000097:blood / Q000175:diagnosis*
chemical_list: D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase