title: Mitosis: towards a molecular understanding of chromosome behavior.
abstract: The past year has seen important contributions made to resolving how chromosomes attach to and move on the mitotic spindle of animal cells. These include the findings that: kinetochore microtubules are derived from the asters (i.e. centrosomes); poleward chromosome motion need not be coupled to kinetochore microtubules disassembly; the motor for poleward chromosome motion is associated with the kinetochore; and immunological evidence that this motor is cytoplasmic dynein.
authors.affiliation: Wadsworth Center for Laboratory Research, New York State Department of Health, Albany.
authors.forename: C L
authors.initials: CL
authors.lastname: Rieder
mesh_terms: D000705:Anaphase / Q000502:physiology; D000818:Animals; D002875:Chromosomes / Q000502:physiology*; D008938:Mitosis / Q000502:physiology*; D008941:Spindle Apparatus / Q000502:physiology