[Immunomorphologic diagnosis of early myocardial necrosis using monoclonal antibodies to desmin and vimentin].
Apart from monoclonal antibodies against cytoskeleton proteins, polyclonal antibodies to gamma-globulin and immunoglobulin G were used. Mosaicism of myocardial damage was observed: the intermittence of acute necrosis foci with areas of ischemia and normal myocardium. Desmin may serve a marker of early necrosis in the myocardium.
Chumachenko
P V
PV
Vikhert
A M
AM
D000368:Aged; D000911:Antibodies, Monoclonal; D015415:Biomarkers / Q000737:chemistry; D003327:Coronary Disease / Q000175:diagnosis / Q000473:pathology; D003893:Desmin / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology*; D009336:Necrosis; D014746:Vimentin / Q000032:analysis*
D000911:Antibodies, Monoclonal; D015415:Biomarkers; D003893:Desmin; D014746:Vimentin
Immunomorfologicheskaia diagnostika rannikh nekrozov miokarda s pomoshch'iu monoklonal'nykh antitel k desminu i vimentinu.