title: [Fecal occult blood--does a hemoglobin-specific tests improve the diagnosis of relevant colonic neoplasms?].
abstract: The object of this study was to assess whether an immunological test specific for human hemoglobin improves the detection of bleeding from colorectal tumors as compared to a conventional guaiac test for occult fecal blood. We examined one stool sample from 134 patients prior to a complete colonoscopy by the Colo-Immun-Test (CI) as well as the Colo-Rectal-Test (CR). CI proved to have a higher sensitivity for occult bleeding from all colonic lesions, but this difference was not statistically significant. There was, however, no difference in the sensitivity of the two tests in detecting bleeding from relevant colonic neoplasms. In this study the immunological CI did not improve the detection of occult fecal blood loss due to adenomas and carcinomas of the colon in comparison with CR.
authors.affiliation: Medizinische Abteilung, St. Claraspital Basel.
authors.forename: B
authors.initials: B
authors.lastname: Gysi
authors.forename: C
authors.initials: C
authors.lastname: Lang
authors.forename: H
authors.initials: H
authors.lastname: Affolter
mesh_terms: D015179:Colorectal Neoplasms / Q000150:complications*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis*; D006801:Humans; D007159:Immunologic Tests; D008297:Male; D008551:Melena / Q000175:diagnosis; D008875:Middle Aged; D009780:Occult Blood; D012680:Sensitivity and Specificity
vernacular_title: Okkultes Blut im Stuhl--Verbessert ein hämoglobinspezifischer Test die Diagnostik relevanter Kolon-Neoplasien?