title: Common variable hypogammaglobulinemia presenting as nontypable Haemophilus influenzae septic arthritis in an adult.
abstract: Haemophilus influenzae is a rare cause of septic arthritis in adults. We describe a case of septic arthritis with nontypable Haemophilus influenzae presenting as the first invasive infection leading to a diagnosis of common variable hypogammaglobulinemia. Although nontypable strains have been shown to cause serious infections in adults, they are a rare cause of septic arthritis. Underlying immune deficiency should be considered in an adult who presents with invasive infection with Haemophilus influenzae, regardless of serotype.
authors.affiliation: Department of Internal Medicine, National Naval Medical Center, Bethesda, MD 20889-5000.
authors.forename: R E
authors.initials: RE
authors.lastname: Hawkins
authors.forename: J D
authors.initials: JD
authors.lastname: Malone
authors.forename: W L
authors.initials: WL
authors.lastname: Ebbeling
mesh_terms: D000328:Adult; D000361:Agammaglobulinemia / Q000175:diagnosis* / Q000473:pathology; D001170:Arthritis, Infectious / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D003937:Diagnosis, Differential; D006192:Haemophilus Infections / Q000175:diagnosis* / Q000473:pathology; D006193:Haemophilus influenzae / Q000145:classification; D006801:Humans; D008297:Male; D012703:Serotyping