Simultaneous determination of sulphathiazole and sulphanilamide in pharmaceuticals by derivative spectrophotometry.
Third-order and fourth-order derivative spectra have been used for determining sulphathiazole, sulphanilamide and their binary mixtures. The method is suitable for 1-22 micrograms ml-1 of sulphathiazole and for 0.5-14 micrograms ml-1 of sulphanilamide and can be applied for determining the sulphonamides in pharmaceuticals.
Berzas Nevado
J J
JJ
Departamento de Química Analítica, Facultad de Ciencias, Universidad de Extremadura, Badajoz, Spain.
Salinas
F
F
de Orbe Paya
I
I
Capitan-Vallvey
L F
LF
D002851:Chromatography, High Pressure Liquid; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents; D012996:Solutions; D013056:Spectrophotometry, Ultraviolet; D013424:Sulfanilamides / Q000032:analysis*; D013432:Sulfathiazoles / Q000032:analysis*; D013607:Tablets
D007202:Indicators and Reagents; D012996:Solutions; D013424:Sulfanilamides; D013432:Sulfathiazoles; D013607:Tablets