Subependymoma with rhabdomyosarcomatous differentiation: report of a case and literature review.
A unique gliomesenchymal neoplasm, consisting of a subependymoma, a form of low-grade glioma, and a rhabdomyosarcoma, is described. It arose and recurred in the brain stem of a 52-year-old man. Immunohistochemical studies demonstrated the presence of a neuroectodermal marker S-100 protein within some sarcoma cells. The occurrence of this rare tumor supports the concept that striated muscle may derive from a neuroectodermal precursor lesion.
Tomlinson
F H
FH
Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota.
Scheithauer
B W
BW
Kelly
P J
PJ
Forbes
G S
GS
D001932:Brain Neoplasms / Q000473:pathology*; D001933:Brain Stem / Q000473:pathology; D005910:Glioma / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D012208:Rhabdomyosarcoma / Q000473:pathology*