Generalized eruptive histiocytoma: a report of a variant case showing the presence of dermal indeterminate cells.
We describe a 14-year-old Japanese girl with a variant of generalized eruptive histiocytoma. She presented with the characteristic features of classical generalized eruptive histiocytoma but with the following minor differences. Clinically, some of the papular eruptions tended to coalesce to form plaques. Histoligically, some of the histiocytic cells were S-100 protein- and OKT-6-positive; these were thought to be indeterminate cells because they lacked Birbeck granules. In addition, PAS-positive cells were few and there were some intermingled lymphocytes and a few eosinophils.
Saijo
S
S
Department of Dermatology, Tohoku University School of Medicine, Sendai, Japan.
Hara
M
M
Kuramoto
Y
Y
Tagami
H
H
D000293:Adolescent; D005260:Female; D005350:Fibroma / Q000737:chemistry / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D009418:S100 Proteins / Q000032:analysis; D012878:Skin Neoplasms / Q000737:chemistry / Q000473:pathology*
D009418:S100 Proteins