[Appraisal and significance of individual reactivity, daily and seasonal fluctuations of biorhythms, age, sex, and force and multiplicity factor of mechanical effects in the development and outcomes of the shock process].
Experiments were conducted on 944 rats on two models of traumatic shock (prolonged crushing of soft tissues of the thighs, shock after Cannon). A diagnostic index of the severity of traumatic shock (K) was elaborated which showed in conditional units (from 0 to 9) the relation of changes of the skin electric resistance before and after the trauma. The types of the animals' responses were determined and classified according to this index. In severe shock K varied from 2 to 3.5 (the survival of animals did not exceed 24 hours). In moderately severe shock it ranged between 0.8 and 2 or 3.5 and 9 (the survival period was 2-3 days). In mild shock this index ranged from 0 to 0.5 (survival period was 4-5 days). The authors determined the informative significance of some criteria for complex evaluation of the severity of the shock in experiments. According to this significance, the criteria stand in the following diminishing sequence: force of the mechanical effect, factors of individual reactivity (pronounced K index, duration of phase two of its fluctuations), age (weight), time of day, season, sex.
Zolotukhin
S E
SE
El'skiĭ
V N
VN
Kriuk
Iu Ia
IuIa
Akishev
A M
AM
Dlugokanskiĭ
D M
DM
D000375:Aging / Q000502:physiology*; D000818:Animals; D001696:Biomechanical Phenomena; D002940:Circadian Rhythm / Q000502:physiology*; D005260:Female; D008297:Male; D011379:Prognosis; D051381:Rats; D012621:Seasons; D012727:Sex Characteristics; D012774:Shock, Traumatic / Q000503:physiopathology*
Otsenka i znachenie individual'noĭ reaktivnosti, sutochnykh, sezonnykh kolebaniĭ bioritmov, vozrasta, pola organizma, sily i kratnosti mekhanicheskikh vozdeĭstviĭ v razvitii i iskhodakh shokovogo protsessa.