title: Sibs with a disorder resembling Blount disease (tibia vara).
abstract: Radiographic investigation of 3 Turkish sibs presenting with bowed legs disclosed physiological tibial bowing in the 7-month-old girl. Stage I Blount disease in the 26 month-old boy and Stage II Blount disease in the 45 month-old girl. The reported cases provide evidence for autosomal recessive inheritance. This observation points to genetic heterogenity, i.e. the existence of 2 genetically different, but radiologically indistinguishable disorders.
authors.affiliation: Department of Pediatrics, University Mainz, FRG.
authors.forename: H
authors.initials: H
authors.lastname: Schmidt
authors.forename: S
authors.initials: S
authors.lastname: Mundlos
authors.forename: J W
authors.initials: JW
authors.lastname: Spranger
mesh_terms: D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D010007:Osteochondritis / Q000000981:diagnostic imaging / Q000235:genetics*; D010020:Osteonecrosis / Q000000981:diagnostic imaging / Q000235:genetics*; D011859:Radiography; D013977:Tibia / Q000000981:diagnostic imaging