title: Neurophysiology of the striated urethral sphincter in multiple sclerosis.
abstract: Urethrovesical dysfunction is common in patients with multiple sclerosis. We present the results of urodynamic and neurophysiological studies in a series of 24 patients with multiple sclerosis associated with urinary symptoms. Urethral sphincter electromyography showed only minor abnormalities but studies of central conduction demonstrated abnormal sensory conduction in 88% and abnormal motor conduction in 80% of the patients studied. These abnormalities of central conduction correlated well with the urodynamic findings.
authors.affiliation: Department of Urology, St Bartholomew's Hospital, London.
authors.forename: I
authors.initials: I
authors.lastname: Eardley
authors.forename: K
authors.initials: K
authors.lastname: Nagendran
authors.forename: B
authors.initials: B
authors.lastname: Lecky
authors.forename: C R
authors.initials: CR
authors.lastname: Chapple
authors.forename: R S
authors.initials: RS
authors.lastname: Kirby
authors.forename: C J
authors.initials: CJ
authors.lastname: Fowler
mesh_terms: D000328:Adult; D004576:Electromyography; D005071:Evoked Potentials / Q000502:physiology; D005073:Evoked Potentials, Somatosensory / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications / Q000503:physiopathology*; D014521:Urethra / Q000294:innervation / Q000503:physiopathology*; D014555:Urination Disorders / Q000209:etiology / Q000503:physiopathology*; D014563:Urodynamics / Q000502:physiology