[Effects of dephosphorylated core of 2',5'-oligoadenylate (2',5'-ApApA) on the electric activity of snail neurons].
On nervous ganglion of snail Helix pomatia was shown the effect of dephosphorylated core of 2',5'-oligoadenylate (2',5'-ApApA) on pacemaker electrical activity of RPa2 snail neurons. In experiments, solution of 2',5'-ApApA in concentration 5 x 10(-5) mol/l effected snail nervous ganglion in the course of 2 min then it was washed in the course of 2 hours.
Iakovenko
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IN
Omel'ianets
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D000227:Adenine Nucleotides / Q000494:pharmacology*; D000818:Animals; D004594:Electrophysiology; D006372:Helix, Snails; D066298:In Vitro Techniques; D008564:Membrane Potentials; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D009843:Oligoribonucleotides / Q000494:pharmacology*; D011500:Protein Synthesis Inhibitors / Q000494:pharmacology*; D013997:Time Factors
D000227:Adenine Nucleotides; D009843:Oligoribonucleotides; D011500:Protein Synthesis Inhibitors; C023505:2',5'-oligoadenylate
Vliianie defosforilirovannogo "kora" 2',5'-oligoadenilata (2', 5'-ApApA) na élektricheskuiu aktivnost' neĭrona ulitki.