title: Radiation therapy for the management of localized prostate carcinoma.
abstract: Radiation therapy has been reported as an effective modality for the curative management of localized prostate carcinoma. In a 6 year period (1982-87), 141 patients with localized prostate carcinoma were treated at Auckland Hospital. Most patients were given radiation to the prostate alone. The overall local failure rate was 14%, with 57 patients developing distant metastases at the time of analysis. Toxicity was generally acceptable but was clearly related to the size of the treatment volume. The 5 year actuarial survival for all patients was 69.5%. Relapse-free survival rate was 39% at 5 years. Clinical stage and histological differentiation were significant factors affecting survival. Histology was a significant factor in local control. Radiation therapy for localized prostate carcinoma is effective, with a high rate of local control and low morbidity.
authors.affiliation: Department of Clinical Oncology, Auckland Hospital, New Zealand.
authors.forename: B H
authors.initials: BH
authors.lastname: Burmeister
authors.forename: J C
authors.initials: JC
authors.lastname: Probert
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011471:Prostatic Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D011829:Radiation Dosage; D012189:Retrospective Studies; D015996:Survival Rate