Effect of 12 hr temporal relation of serotonin and dopamine precursor drugs (5-HTP and L-DOPA) on photosexual responses of immature Japanese quail.
To study the interaction of photoperiod and circadian neurotransmitter activity, L-DOPA L-dihydroxyphenylalanine, dopamine precursor) was administered daily, 12 hr after 5-HTP (5-hydroxy tryptophan, serotonin precursor) in sexually immature Japanese quail, raised under short photoperiod (LD8:16) since hatching. The 12 hr treatment of 5-HTP and L-DOPA was given under continuous condition of light for 11 days. After treatment the quail were transferred to intermediate day length (LD 13.5:10.5). The cloacal gland size of drug treated group increased significantly in comparison to control. The quail were then transferred to short photoperiod (LD 8:16). The cloacal gland size of both the groups started decreasing gradually but the rate was significantly low in drug treated quail in comparison to control. The results indicate that the endogenous mechanism controlling seasonality may be reset by drugs that influence serotonergic and dopaminergic activity. The 12 hr relation between the two drugs is stimulatory for gonadal growth under intermediate day length and retards the rate of regression when transferred to short days.
Chaturvedi
C M
CM
Department of Zoology, Banaras Hindu University, Varanasi, India.
Meier
A H
AH
Bhatt
R
R
D006916:5-Hydroxytryptophan / Q000494:pharmacology*; D000818:Animals; D002940:Circadian Rhythm; D002988:Cloaca / Q000033:anatomy & histology / Q000187:drug effects / Q000378:metabolism; D003370:Coturnix; D007980:Levodopa / Q000494:pharmacology*; D008297:Male; D012098:Reproduction / Q000187:drug effects / Q000502:physiology*; D013737:Testis / Q000033:anatomy & histology / Q000187:drug effects / Q000378:metabolism
D007980:Levodopa; D006916:5-Hydroxytryptophan