Calcitonin gene-related peptide immunoreactivity in a crustacean Nephrops norvegicus and correlation with calcitonin.
Immunoreactive calcitonin-gene-related peptide (ir-CGRP) was detected in the crustacean Nephrops norvegicus. High levels of ir-CGRP were present in the foregut and hepatopancreas (3 +/- 0.7 and 4.6 +/- 1.0 micrograms eq per 100 mg of fresh organ, respectively). Molecular sieving of acidic extracts of anterior gut of Nephrops norvegicus showed a high molecular weight immunoreactive peptide in the range 15,000 to 25,000 Da. Immunoreactivity related to salmon calcitonin was present in the high molecular weight fraction.
Arlot-Bonnemains
Y
Y
URA 174, CHU St. Antoine, Paris, France.
Fouchereau-Peron
M
M
Chesnais
J
J
Taboulet
J
J
Milhaud
G
G
Moukhtar
M S
MS
D000818:Animals; D001001:Anura; D002116:Calcitonin / Q000032:analysis; D015740:Calcitonin Gene-Related Peptide / Q000032:analysis*; D002645:Chickens; D002850:Chromatography, Gel; D004064:Digestive System / Q000737:chemistry*; D005399:Fishes; D006801:Humans; D008121:Nephropidae / Q000378:metabolism*; D011863:Radioimmunoassay; D051381:Rats; D012474:Salmon / Q000378:metabolism
D002116:Calcitonin; D015740:Calcitonin Gene-Related Peptide