The immunopathogenesis of AIDS.
In summary, the understanding of the pathogenesis of immune dysfunction in HIV infection is incomplete. New mechanisms by which HIV disrupts the immune system through alterations in basic biochemical events in CD4 T cells are continually being discovered. In a positive light, because of the complexity involved in HIV-mediated induction of immune suppression, logic suggests there is potential for reversing some of these processes.
Baker
J R
JR
Department of Medicine, University of Michigan Medical Center, Ann Arbor.
Leigh
T
T
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology*; D000917:Antibody Formation; D006678:HIV / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular