Amniotic cavity accumulation of magnesium with prolonged magnesium sulfate tocolysis.
In seven women, continuous intravenous tocolysis with magnesium sulfate for 4-28 days resulted in high amniotic fluid magnesium levels (10.54 mg% +/- 1.83 SD). In all cases the amniotic fluid magnesium level greatly exceeded the maternal serum level in a sample collected simultaneously. Additionally, when amniorrhexis and delivery occurred within one hour of each other, the fetal magnesium levels uniformly exceeded the maternal levels in paired maternal and cord blood samples.
Hankins
G D
GD
Department of Obstetrics and Gynecology, Wilford Hall United States Air Force Medical Center, Lackland Air Force Base, Texas 78236-5300.
Hammond
T L
TL
Yeomans
E R
ER
D000328:Adult; D000653:Amniotic Fluid / Q000737:chemistry*; D002118:Calcium / Q000097:blood / Q000737:chemistry; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D005865:Gestational Age; D006801:Humans; D008278:Magnesium Sulfate / Q000009:adverse effects* / Q000097:blood / Q000737:chemistry; D010298:Parity; D011247:Pregnancy / Q000097:blood; D015145:Tocolysis / Q000009:adverse effects*
D008278:Magnesium Sulfate; D002118:Calcium