Chorea as a manifestation of the antiphospholipid syndrome in childhood.
Chorea has been related to the presence of antiphospholipid antibodies (a-PL) in the context of systemic lupus erythematosus (SLE). Here we report the case of a 13-year-old girl with a-PL antibodies, who had developed thrombophlebitis at the age of 11 years and chorea two years later, in the absence of clinically evident SLE. Serological tests revealed a false positive test for syphilis, a prolonged activated partial thromboplastin time, hypocomplementaemia and positive anti-DNA antibodies.
Vlachoyiannopoulos
P G
PG
Department of Medicine, School of Medicine, University of Ioannina, Greece.
Dimou
G
G
Siamopoulou-Mavridou
A
A
D000293:Adolescent; D000906:Antibodies / Q000276:immunology*; D000974:Antibodies, Antinuclear / Q000276:immunology; D001327:Autoimmune Diseases / Q000150:complications / Q000276:immunology / Q000473:pathology*; D002819:Chorea / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D003165:Complement System Proteins / Q000276:immunology; D005260:Female; D006801:Humans; D010314:Partial Thromboplastin Time; D010743:Phospholipids / Q000276:immunology*; D013577:Syndrome; D013924:Thrombophlebitis / Q000150:complications / Q000276:immunology / Q000473:pathology
D000906:Antibodies; D000974:Antibodies, Antinuclear; D010743:Phospholipids; D003165:Complement System Proteins