Influence of pineal peptides on the dynamics of the circadian and minute motor biorhythms in rats.
A peptide preparation of the pineal, epithalamin, when administered chronically, exerts a modulating influence on the diurnal fluctuations of the motoric activity of rats. It also decreases the amplitude of apomorphine stereotypy and induces a restructuring of a modulatory character in its rhythmic structure. It is hypothesized that the pineal peptides participate in the maintenance of homeostasis by means of the stabilization of rhythmic processes of various periods.
Arushanyan
E B
EB
Department of the Pharmacology of the Vestibular Apparatus, State Medical Institute, Stavropol.
Baturin
V A
VA
Ovanesov
K B
KB
D000818:Animals; D001058:Apomorphine / Q000494:pharmacology; D002940:Circadian Rhythm / Q000187:drug effects*; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D010455:Peptides / Q000494:pharmacology*; D010507:Periodicity; D010870:Pineal Gland / Q000502:physiology*; D051381:Rats; D013239:Stereotyped Behavior / Q000187:drug effects
D010455:Peptides; C027437:epithalamin; D001058:Apomorphine