The significance of nuclear grooves and phagocytosis in the diagnosis of metastatic papillary carcinoma of the thyroid.
A 57-year-old patient presented with a lesion of the iliac bone. Cytological smears prepared from material aspirated from the lesion revealed cells with longitudinal nuclear grooves and haemosiderin within their cytoplasm. These observations led to a diagnosis of metastatic thyroid papillary carcinoma which was confirmed by histological examination.
Chetty
R
R
Department of Anatomical Pathology, University of Cape Town, South Africa.
Learmonth
G M
GM
Kalan
M R
MR
D001859:Bone Neoplasms / Q000473:pathology / Q000556:secondary* / Q000648:ultrastructure; D002291:Carcinoma, Papillary / Q000473:pathology / Q000556:secondary* / Q000648:ultrastructure; D002467:Cell Nucleus / Q000473:pathology; D006485:Hemosiderin / Q000032:analysis; D006801:Humans; D007085:Ilium / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000473:pathology*
D006485:Hemosiderin