title: Effect of hydrocortisone on the axial organ of the sea star Asterias rubens.
abstract: Sea stars Asterias rubens were inoculated daily with hydrocortisone. After 3 days a plaque of lysis was formed in the center of the axial organ and increased in size if the injections were continued for 2 more days. This result is reminiscent of the effect of cortisone on the thymus of vertebrates and supports the hypothesis that the axial organ is an ancestral lymphoid tissue.
authors.forename: M
authors.initials: M
authors.lastname: Leclerc
authors.forename: M
authors.initials: M
authors.lastname: Bajelan
mesh_terms: D000818:Animals; D006854:Hydrocortisone / Q000494:pharmacology*; D008221:Lymphoid Tissue / Q000187:drug effects*; D013215:Starfish / Q000187:drug effects*
chemical_list: D006854:Hydrocortisone