Acute nonhemodynamic pulmonary edema with nifedipine in primary pulmonary hypertension.
A 34-year-old man with primary pulmonary hypertension developed acute nonhemodynamic pulmonary edema after a loading dose of nifedipine. Changes of the vascular permeability induced by the drug acting on the arteriolar wall of the capillary system could be an explanation.
Prigogine
T
T
Department of Medicine, Cl.E. Cavell, Brussels, Belgium.
Waterlot
Y
Y
Gottignies
P
P
Verhoeven
A
A
Decroly
P
P
D000208:Acute Disease; D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D009543:Nifedipine / Q000008:administration & dosage / Q000009:adverse effects*; D011651:Pulmonary Artery / Q000503:physiopathology; D011654:Pulmonary Edema / Q000139:chemically induced*; D011669:Pulmonary Wedge Pressure / Q000187:drug effects; D014655:Vascular Resistance / Q000187:drug effects
D009543:Nifedipine