[Changes in lipid peroxides and superoxide dismutase as incubation of in vitro erythrocytes with cerebrospinal fluids and the action of various scavengers of free radicals].
In this experiment, LPO increased and SOD reduced as the time pass when erythrocytes (RBC) and CSF were mixed and incubated. There was a negative relationship between LPO and SOD. LPO in RBC of arterial blood was higher than that of venous blood after incubation for 3 days (P less than 0.01). When arterial RBCs were incubated together with various scavengers of free radical (SOD catalase and histidine and mannitol), the production of LPO was less than that of arterial RBC incubation singly (P less than 0.01). The change of LPO was not reduced when sodium nitrite and arterial RBC incubated. The results demonstrated that the scavengers of free radicals could be eliminated free radical but failed with sodium nitrite.
Bao
Y D
YD
First Affiliated Hospital of Shuzhou Medical College.
Jiang
K
K
D000818:Animals; D002555:Cerebrospinal Fluid; D004912:Erythrocytes / Q000201:enzymology / Q000378:metabolism*; D016166:Free Radical Scavengers; D008054:Lipid Peroxides / Q000378:metabolism*; D011817:Rabbits; D013482:Superoxide Dismutase / Q000378:metabolism*
D016166:Free Radical Scavengers; D008054:Lipid Peroxides; D013482:Superoxide Dismutase