title: Multigated blood-pool imaging using heart sounds.
abstract: A method to trigger multigated blood-pool (MGBP) acquisition using both the first and second heart sound has been developed. The heart sound gating (HSG) circuitry identifies, individually, both the first (S1) and second (S2) heart sounds from their timing relationship alone, and provides two trigger points during the cardiac cycle. First heart sound gating may be performed to assess the systolic ejection portion of the cardiac cycle, with S2 gating utilized for reproduction of the diastolic filling portion of the cycle. Heart sound gating has been applied to twenty patients who underwent analysis of left ventricular function, and compared to conventional ECG-gated MGBP. Left ventricular ejection fractions calculated from MGBP studies using a first and a second heart sound trigger correlated well with conventional ECG gated acquisitions in patients adequately gated by HSG and ECG. Heart sound gating may be utilized in patients with rapidly changing heart rates, as S1 and S2 precisely define end-diastole and end-systole, respectively, and in situations when the ECG is inadequate for gating purposes.
authors.affiliation: Rush Graduate College, Department of Medical Physics Rush Presbyterian-St Luke's Medical Center, Chicago, Illinois 60612.
authors.forename: M W
authors.initials: MW
authors.lastname: Groch
authors.forename: J R
authors.initials: JR
authors.lastname: Domnanovich
authors.forename: W D
authors.initials: WD
authors.lastname: Erwin
authors.forename: A
authors.initials: A
authors.lastname: Ali
authors.forename: D A
authors.initials: DA
authors.lastname: Turner
mesh_terms: D004562:Electrocardiography; D015637:Gated Blood-Pool Imaging / Q000379:methods*; D006321:Heart / Q000000981:diagnostic imaging*; D006347:Heart Sounds; D006801:Humans; D010701:Phonocardiography; D013318:Stroke Volume / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology*