title: Acid phosphatase, adenosine deaminase and esterase D polymorphisms in the Spanish Basque population.
abstract: The 3 red-cell polymorphic systems acid phosphatase (ACP), adenosine deaminase (ADA) and esterase D (ESD) have been studied in a random sample of 1,112 individuals from the Basque country: The allelic frequencies obtained were ACP*A = 0.275, ACP*B = 0.718 and ACP*C = 0.007; ADA*2 = 0.021, and, ESD*2 = 0.066. The allelic frequencies have been compared with those of other Basque and other European populations. In comparison with Basques, significant differences were detected only for ACP, whereas as regards other Europeans significant differences were obtained with practically all the populations compared for the 3 genetic systems studied. The low values of the less frequent alleles, especially that for the ACP*C allele which is the lowest reported in Europe, are noteworthy.
authors.affiliation: Departamento de Biología Animal y Genética, Universidad del País Vasco, Spain.
authors.forename: A I
authors.initials: AI
authors.lastname: Aguirre
authors.forename: A
authors.initials: A
authors.lastname: Vicario
authors.forename: L I
authors.initials: LI
authors.lastname: Mazón
authors.forename: M M
authors.initials: MM
authors.lastname: de Pancorbo
authors.forename: A
authors.initials: A
authors.lastname: Estomba
authors.forename: C
authors.initials: C
authors.lastname: Lostao
mesh_terms: D000135:Acid Phosphatase / Q000235:genetics*; D000243:Adenosine Deaminase / Q000235:genetics*; D043182:Carboxylesterase; D002265:Carboxylic Ester Hydrolases / Q000235:genetics*; D004912:Erythrocytes / Q000201:enzymology*; D005787:Gene Frequency / Q000235:genetics; D014644:Genetic Variation / Q000235:genetics; D005828:Genetics, Population; D006801:Humans; D011110:Polymorphism, Genetic / Q000235:genetics; D013030:Spain
chemical_list: D002265:Carboxylic Ester Hydrolases; D043182:Carboxylesterase; C020118:ESD protein, human; D000135:Acid Phosphatase; D000243:Adenosine Deaminase