title: Cytochemical and immunocytochemical characterization of Yoshida ascites sarcoma cells.
abstract: Some cytochemical and immunocytochemical investigations were carried out on actively growing Yoshida ascites sarcoma cells. These cells displayed an intense granular alpha-naphthylacetate esterase (ANAE) staining while the alpha-naphthylbutyrate esterase (ANBE) reaction was in part fluoride-sensitive and marked particularly in the large-size malignant cells. Acid phosphatase as well as peroxidase activities were not detected. The lack of immunoreactive lysozyme and alpha 1-antitrypsin suggested a poor differentiation of the above-mentioned tumor cells, but fibronectin and S-100 protein where highly expressed, as in tumors arising from the mononuclear phagocyte system.
authors.affiliation: Department of Human Pathology, University of Messina, Italy.
authors.forename: P A
authors.initials: PA
authors.lastname: Nicotina
authors.forename: P
authors.initials: P
authors.lastname: Ruggeri
authors.forename: G
authors.initials: G
authors.lastname: Ferlazzo
authors.forename: V
authors.initials: V
authors.lastname: Fimiani
mesh_terms: D000818:Animals; D001201:Ascites; D002265:Carboxylic Ester Hydrolases / Q000737:chemistry; D005260:Female; D005353:Fibronectins / Q000737:chemistry; D008297:Male; D009283:Naphthol AS D Esterase / Q000737:chemistry; D051381:Rats; D011919:Rats, Inbred Strains; D009418:S100 Proteins / Q000737:chemistry; D012517:Sarcoma, Yoshida / Q000737:chemistry* / Q000276:immunology
chemical_list: D005353:Fibronectins; D009418:S100 Proteins; D009283:Naphthol AS D Esterase; D002265:Carboxylic Ester Hydrolases; C021855:naphthylbutyrate esterase