title: Etretinate and visual function: a 1-year follow-up study.
abstract: Concern has been expressed in the literature that the drug etretinate may be potentially retinotoxic. Four patients are reported who have received long-term treatment with etretinate and who have undergone detailed evaluation for the development of visual dysfunction over a 1-year period. Despite prolonged treatment and high total doses no evidence of ocular toxicity attributable to the drug was found in any of the patients.
authors.affiliation: Tennent Institute of Ophthalmology, Western Infirmary, Glasgow, U.K.
authors.forename: J F
authors.initials: JF
authors.lastname: Pitts
authors.forename: R M
authors.initials: RM
authors.lastname: Mackie
authors.forename: G N
authors.initials: GN
authors.lastname: Dutton
authors.forename: E A
authors.initials: EA
authors.lastname: McClure
authors.forename: D
authors.initials: D
authors.lastname: Allan
mesh_terms: D004476:Ectodermal Dysplasia / Q000188:drug therapy; D004890:Erythema / Q000188:drug therapy; D005050:Etretinate / Q000009:adverse effects* / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D011565:Psoriasis / Q000188:drug therapy; D012160:Retina / Q000187:drug effects; D014786:Vision Disorders / Q000139:chemically induced*; D014785:Vision, Ocular / Q000187:drug effects; D014792:Visual Acuity / Q000187:drug effects; D014794:Visual Fields / Q000187:drug effects
chemical_list: D005050:Etretinate