[Gentamicin kinetics in the blood and aqueous humor of the rabbit eye after intramuscular and subconjunctival administration].
Investigations were performed in rabbits which were given gentamycin intramuscularly and subconjunctivally. After subconjunctival application gentamycin passes quickly into the eye and its therapeutical level persists up to 1 hour. After intramuscular injection gentamycin is passing slower into the aqueous but persists there longer (the therapeutical level--up to 5.5 hours).
Sieradzki
E
E
Zakładu Farmacji Aptecznej Studium Farmaceutycznego CMKP, Bydgoszczy.
Strauss
K
K
Olejarz
E
E
Pankowska
I
I
Pankowski
M
M
Kałuzny
J
J
D000818:Animals; D001082:Aqueous Humor / Q000378:metabolism*; D003228:Conjunctiva / Q000187:drug effects; D005839:Gentamicins / Q000008:administration & dosage / Q000378:metabolism / Q000493:pharmacokinetics*; D007267:Injections; D007273:Injections, Intramuscular; D008954:Models, Biological; D011817:Rabbits; D013997:Time Factors
D005839:Gentamicins
Kinetyka gentamycyny w krwi i cieczy wodnistej oka królika podanej domieśniowo i podspojówkowo.