[The interference of miocamycin on the adhesiveness and coaggregation of the bacteria responsible for periodontopathies].
The authors studied the effect miocamycin has on the adherence and coaggregation of pathogenic bacteria in periodontopathy. The data obtained by optic microscopy, after treatment of the strains with doses of miocamycin equal to 1/4 and 1/8 of the MIC after 3 and 6 hours, shows the interference effect on the coaggregation and adhesivity of the antibiotic. These results have been confirmed by the observations obtained by scanning electron microscope (SEM).
Chisari
G
G
Istituto di Microbiologia, Università di Catania.
Drago
L
L
Lo Bue
A M
AM
Gismondo
M R
MR
D001419:Bacteria / Q000187:drug effects* / Q000302:isolation & purification / Q000472:pathogenicity / Q000648:ultrastructure; D001422:Bacterial Adhesion / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods; D008855:Microscopy, Electron, Scanning; D015644:Miocamycin / Q000494:pharmacology*; D010510:Periodontal Diseases / Q000209:etiology / Q000382:microbiology*; D013997:Time Factors
D015644:Miocamycin
Interferenza di miocamicina sull'adesività e sulla coaggregazione di germi responsabili di parodontopatie.