title: Sequence of the Candida albicans gene encoding the secretory aspartate proteinase.
abstract: The gene encoding the Candida albicans aspartate proteinase that is secreted by cells grown in protein-containing media was cloned from a C. albicans genomic bank. The base sequence of the insert shows a 1173 bp open-reading frame and indicates an amino acid sequence typical of aspartate proteinases, with amino acid sequence homology to other enzymes of this class and a putative signal peptide consisting of 50 amino acids upstream of the active enzyme.
authors.affiliation: Hygiene-Institut der Universität, Göttingen, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Hube
authors.forename: C J
authors.initials: CJ
authors.lastname: Turver
authors.forename: F C
authors.initials: FC
authors.lastname: Odds
authors.forename: H
authors.initials: H
authors.lastname: Eiffert
authors.forename: G J
authors.initials: GJ
authors.lastname: Boulnois
authors.forename: H
authors.initials: H
authors.lastname: Köchel
authors.forename: R
authors.initials: R
authors.lastname: Rüchel
mesh_terms: D000595:Amino Acid Sequence; D016282:Aspartic Acid Endopeptidases / Q000235:genetics*; D001483:Base Sequence; D002176:Candida albicans / Q000201:enzymology / Q000235:genetics*; D003001:Cloning, Molecular; D003470:Culture Media; D004271:DNA, Fungal / Q000737:chemistry*; D008969:Molecular Sequence Data; D015345:Oligonucleotide Probes; D016366:Open Reading Frames; D016133:Polymerase Chain Reaction; D021382:Protein Sorting Signals / Q000235:genetics
chemical_list: D003470:Culture Media; D004271:DNA, Fungal; D015345:Oligonucleotide Probes; D021382:Protein Sorting Signals; D016282:Aspartic Acid Endopeptidases