Production of self-migration stimulating factor by metastatic human malignant melanoma cells established in culture.
Establishment of human malignant melanoma of hard palate cell line derived from metastatic foci in lymph node is reported. We name it HM162. The shape of HM162 was almost spindle. HM162 cells secreted a factor into culture medium which stimulates motility of HM162 cell itself, and the mode of stimulated migration of HM162 cells were activated random migration, that is chemokinesis.
Yoshikawa
F
F
Second Department of Oral and Maxillofacial Surgery, Osaka University Faculty of Dentistry, Japan.
Sakuda
M
M
D002465:Cell Movement; D006801:Humans; D008545:Melanoma / Q000378:metabolism* / Q000473:pathology; D014407:Tumor Cells, Cultured