[The usefulness of measuring fructosamine in the cord blood of the newborn infants of diabetic mothers].
The aim of our study was to evaluate the usefulness of fructosamine measurement (Fram) in cord blood as an index of glucose metabolism in the last week of pregnancy in infants of diabetic mothers. In newborns and their respective mothers Fram values were surprisingly greater in N than in IDM and IGDM and neonatal and maternal values appeared to be strictly related. While intrauterine growth was associated with metabolic control indexes of 2nd and 3rd trimester gestation. Fram value appeared positively correlated to cord insulin. In conclusion Fram level appears as a good index of glucose metabolic control of the last week of pregnancy and it is associated to cord insulin level and to neonatal hypoglycemia.
Beccaria
L
L
Clinica Pediatrica III, Università degli Studi di Milano.
Corbella
E
E
Poloniato
A
A
Bosio
L
L
Castiglioni
M T
MT
Natale
N
N
Bianchi
C
C
D001786:Blood Glucose / Q000032:analysis; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000188:drug therapy; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D019270:Fructosamine; D006595:Hexosamines / Q000097:blood*; D006801:Humans; D007003:Hypoglycemia / Q000097:blood; D007231:Infant, Newborn; D007328:Insulin / Q000627:therapeutic use; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D011254:Pregnancy in Diabetics / Q000097:blood* / Q000188:drug therapy; D013997:Time Factors
D001786:Blood Glucose; D006595:Hexosamines; D007328:Insulin; D019270:Fructosamine
Utilità del dosaggio delle fruttosamine su sangue funicolare in neonati figli di madre diabetica.