[Analysis of morphometric indices in mice for registration of induced mutations in germ cells].
The new-born mice of the first generation have been examined for changes in morphometric indices after the influence of fopurine, cyclophosphamide and cadmium chloride on their fathers. It is shown that fopurine and cyclophosphamide, the mutagens for mammals, increase the variability of morphometric indices. The method to calculate the morphometric indices of mice may be used for evaluating genetic risk of the compounds for man.
Suraĭkina
T I
TI
Bobrinoev
E V
EV
Skorobogatova
S B
SB
Zolotareva
G N
GN
D000818:Animals; D000831:Animals, Newborn / Q000033:anatomy & histology*; D001388:Aziridines / Q000633:toxicity; D002104:Cadmium / Q000633:toxicity; D019256:Cadmium Chloride; D003520:Cyclophosphamide / Q000633:toxicity; D008297:Male; D051379:Mice; D009153:Mutagens / Q000633:toxicity*; D009154:Mutation; D011687:Purines / Q000633:toxicity; D013094:Spermatozoa / Q000187:drug effects*
D001388:Aziridines; D009153:Mutagens; D011687:Purines; D002104:Cadmium; C015893:pumitepa; D003520:Cyclophosphamide; D019256:Cadmium Chloride
Analiz morfometricheskikh priznakov mysheĭ dlia ucheta indutsirovannykh mutatsiĭ v zarodyshevykh kletkakh.