title: [The status of free radical processes in the pulmonary surfactant system in chronic bronchitis patients].
abstract: Lipid peroxidation-antioxidants were studied in condensed expired air of patients with chronic bronchitis. Under conditions of bronchopulmonary system impairment considerable activation of lipid peroxidation occurred in surface-active lung layers. These processes were elevated during development of the bronchial obstruction syndrome. Alterations of lipid peroxidation were amplified in patients with chronic bronchitis as functional impairments of the respiratory system increased. The antiradical defense system of lung surfactant was found to correlate inversely with the disease duration and severity of respiratory insufficiency.
authors.forename: B S
authors.initials: BS
authors.lastname: Khyshiktuev
authors.forename: V N
authors.initials: VN
authors.lastname: Ivanov
authors.forename: M Z
authors.initials: MZ
authors.lastname: Zhits
mesh_terms: D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000378:metabolism*; D001991:Bronchitis / Q000378:metabolism* / Q000503:physiopathology; D002908:Chronic Disease; D005609:Free Radicals; D006801:Humans; D015227:Lipid Peroxidation; D008875:Middle Aged; D011663:Pulmonary Surfactants / Q000378:metabolism*; D012119:Respiration
chemical_list: D000975:Antioxidants; D005609:Free Radicals; D011663:Pulmonary Surfactants
vernacular_title: Sostoianie svobodnoradikal'nykh protsessov v sisteme legochnogo surfaktanta u bol'nykh khronicheskim bronkhitom.