Hypercoagulability in a patient with Marfan syndrome.
A 39 year old man with Marfan syndrome presented with multiple pulmonary emboli and renal, hepatic, and splenic infarcts of unknown aetiology. The combination of thromboemboli and physical features initially suggested homocystinuria; however, laboratory examination showed no evidence for this disorder. Laboratory evaluation identified no coagulation abnormalities. This patient represents the unusual occurrence of hypercoagulability in a patient with Marfan syndrome.
Humphries
J E
JE
Department of Internal Medicine, University of Virginia School of Medicine, Box 34, Charlottesville 22908.
Stouffer
G A
GA
Kelly
T E
TE
Rose
C E
CE
D000328:Adult; D003937:Diagnosis, Differential; D006712:Homocystinuria / Q000175:diagnosis; D006801:Humans; D007238:Infarction / Q000209:etiology* / Q000235:genetics; D008297:Male; D008382:Marfan Syndrome / Q000097:blood* / Q000150:complications / Q000175:diagnosis; D011655:Pulmonary Embolism / Q000209:etiology / Q000235:genetics; D013923:Thromboembolism / Q000209:etiology* / Q000235:genetics