title: [Immunohistochemical characteristics of the epithelial transformation zone in the uterine cervix using monoclonal antibodies against various epithelial markers].
abstract: Epithelium transformation zone in the uterine cervix was studied by means of monoclonal antibodies (MAB) against cytokeratin (CK) peptides, epithelial membrane antigen (EMA) and skin granular layer proteins. It is shown that in the region of epithelial junction metaplastic epithelium is, as a rule, observed which possesses a unique spectrum of CK distinct from that in the ecto--and endocervix. The features of the expression of CK N8, N17, EMA in metaplasia are described. MAB EE 2I-06 against CK N1, 2, 9-11 and MAB G 36-19 are suggested as markers of the metaplastic epithelium maturity in the uterine cervix.
authors.forename: S V
authors.initials: SV
authors.lastname: Petrov
authors.forename: N T
authors.initials: NT
authors.lastname: Raĭkhlin
authors.lastname: Serre Dzh
mesh_terms: D000328:Adult; D000911:Antibodies, Monoclonal; D015415:Biomarkers / Q000737:chemistry; D002584:Cervix Uteri / Q000737:chemistry*; D004848:Epithelium / Q000737:chemistry; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged
chemical_list: D000911:Antibodies, Monoclonal; D015415:Biomarkers
vernacular_title: Immunogistokhimicheskaia kharakteristika zony transformatsii épiteliia sheĭki matki s pomoshch'iu monoklonal'nykh antitel k razlichnym épitelial'nym markeram.