[Flow cytometric DNA content analysis in thyroid carcinoma].
DNA content and proportion of Phase S cells in 69 paraffin embedded thyroid tumors (15 adenomas and 64 adenocarcinomas) were analysed by flow cytometry. The results showed that 14/15 adenomas were diploid; DNA content was abnormal in 1 papillary adenoma (DNA index 1.14). In the 64 cases of adenocarcinomas, 53 were aneuploid and 11 near diploid. The DNA content and proportion of Phase S cells were closely related to degree of malignancy and prognosis.
Zuo
L F
LF
Hebei Cancer Institute, Shijiazhuang.
D000230:Adenocarcinoma / Q000235:genetics / Q000473:pathology; D000782:Aneuploidy; D002277:Carcinoma / Q000235:genetics / Q000473:pathology; D002291:Carcinoma, Papillary / Q000235:genetics / Q000473:pathology; D004273:DNA, Neoplasm / Q000032:analysis*; D005434:Flow Cytometry; D006801:Humans; D011379:Prognosis; D016196:S Phase; D013964:Thyroid Neoplasms / Q000235:genetics* / Q000473:pathology
D004273:DNA, Neoplasm