title: Interference with sawfly (Arge pullata) poisoning in Fasciola hepatica-infected lambs.
abstract: Lambs harbouring an 8-week-old infection with Fasciola hepatica, together with fluke-free animals, were dosed orally with 2 g per kg body weight of sawfly larvae (Arge pullata). Fluke-free, non-dosed lambs and lambs infected only with F. hepatica served as controls. Clinico-pathological observations on sawfly-dosed, fluke-free lambs revealed the characteristic picture of sawfly poisoning. Four of six animals had to be killed in extremis. In contrast, sawfly-dosed, fluke-infected lambs exhibited only moderate clinico-pathological signs of sawfly poisoning and no deaths occurred. A reduction in the sawfly-induced liver pathology as a consequence of the concurrent F. hepatica infection was also noted. Possible factors responsible for the antagonistic effect of F. hepatica infection on sawfly poisoning in lambs are discussed.
authors.affiliation: Institute of Microbiology and Hygiene, Royal Veterinary and Agricultural University, Copenhagen, Denmark.
authors.forename: F V
authors.initials: FV
authors.lastname: Olaechea
authors.forename: S M
authors.initials: SM
authors.lastname: Thamsborg
authors.forename: N O
authors.initials: NO
authors.lastname: Christensen
authors.forename: P
authors.initials: P
authors.lastname: Nansen
authors.forename: A
authors.initials: A
authors.lastname: Robles
mesh_terms: D000818:Animals; D004798:Enzymes / Q000097:blood; D005210:Fasciola hepatica / Q000469:parasitology*; D005211:Fascioliasis / Q000662:veterinary*; D005243:Feces / Q000469:parasitology; D006790:Host-Parasite Interactions; D006927:Hymenoptera; D007814:Larva; D008099:Liver / Q000201:enzymology / Q000473:pathology; D008297:Male; D012756:Sheep; D012757:Sheep Diseases / Q000097:blood / Q000469:parasitology* / Q000473:pathology
chemical_list: D004798:Enzymes