Pre-clinical toxicity of IDPH-791: a new centrally acting muscle relaxant in rats.
IDPH-791, a novel centrally acting muscle relaxant, in doses up to 500 mg/kg (po) for 14 days did not result in any appreciable adverse effect on body weight gain, food or water consumption including biochemical and haematologica parameters in rats. Variations observed in the biochemistry and haematology were either comparable to controls or were within normal limits.
Varma
R K
RK
Biology Division, IDPL Research Centre, Hyderabad, India.
Rajasekaran
M
M
Junnarkar
A Y
AY
Singh
P P
PP
Krishnamurthy
A
A
Thapar
G S
GS
Marathe
M R
MR
D000818:Animals; D005260:Female; D008297:Male; D009125:Muscle Relaxants, Central / Q000633:toxicity*; D051381:Rats; D011919:Rats, Inbred Strains; D013843:Thiazines / Q000633:toxicity*; D014230:Triazoles / Q000633:toxicity*
D009125:Muscle Relaxants, Central; D013843:Thiazines; D014230:Triazoles; C070154:IDPH-791