title: Fracture healing of chick femurs in tissue culture.
abstract: Embryonic chick femurs were isolated, and a transverse osteotomy was performed at the midshaft. The femurs were transplanted individually onto the host chorioallantoic membrane and incubation continued. Cultured femurs were harvested at intervals from 1 to 9 days after the transplant. Histologic examinations showed that repair progressed rapidly: the fracture gap was invaded by blood vessels and fibrous ingrowth. Ossification followed, and the repair process was completed by Day 9.
authors.affiliation: Department of Orthopedics, Nagasaki University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
authors.forename: M D
authors.initials: MD
authors.lastname: Shanahan
authors.forename: L A
authors.initials: LA
authors.lastname: Coulton
authors.forename: T
authors.initials: T
authors.lastname: Duckworth
mesh_terms: D000481:Allantoin; D000818:Animals; D002146:Bony Callus / Q000033:anatomy & histology / Q000502:physiology; D002642:Chick Embryo; D002823:Chorion; D046508:Culture Techniques; D004195:Disease Models, Animal; D004531:Eggs; D005264:Femoral Fractures / Q000473:pathology* / Q000503:physiopathology; D010012:Osteogenesis / Q000502:physiology; D014945:Wound Healing / Q000502:physiology*
chemical_list: D000481:Allantoin