[Complete remission of lung metastases of bladder tumor treated by small dosage of UFT: a case report].
The patient was a 61-year-old woman with bladder cancer presenting in stage pT3a, N0, M0, T.C.C. (GIII) greater than S.C.C. Following total cystectomy and one course of cisplatin, adriamycin, cyclophosphamide (CAP) as adjuvant chemotherapy, she was started on futraful and uracil (UFT) at a dose of 4 capsules daily and placed on observation. Since she complained of olfactory anesthesia at 2 months of treatment, the dosage of UFT was reduced to 2 capsules daily and the drug was withdrawn after another 2 months of treatment. With the detection of lung metastases one month later UFT was resumed at a dose of 2 capsules daily. At 4 months of resumed treatment the foci of metastasis completely disappeared. She has since shown a complete remission by small dosage of UFT (2 capsules daily) for 12 months or more.
Fukuoka
H
H
Department of Urology, Yokohama Minami Kyosai Hospital.
Takeda
M
M
Nomura
S
S
Ogawa
T
T
Sakanishi
S
S
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002295:Carcinoma, Transitional Cell / Q000188:drug therapy / Q000556:secondary*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary*; D008875:Middle Aged; D012074:Remission Induction / Q000379:methods; D005641:Tegafur / Q000627:therapeutic use; D014498:Uracil / Q000627:therapeutic use; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery
D005641:Tegafur; D014498:Uracil