title: Disseminated infection with Neospora caninum in a ten-year-old dog.
abstract: Naturally-occurring neosporosis with multiple organ involvement was identified in a 10-year-old neutered male Basset hound dog. Clinical signs were first noticed 3 weeks prior to referral and consisted of crouched stance and mild pelvic limb ataxia. Dexamethasone administration had provided transient improvement. On presentation to the teaching hospital, clinical signs included depression, pelvic limb ataxia, inability to stand without assistance, and pain on deep palpation of the cervical and lumbar vertebral column. Lesions were found in the myocardium, liver, spleen, adrenal glands, brain, and spinal cord. Tachyzoites of Neospora caninum were found in the myocardium and adrenal glands. Organisms stained with anti-Neospora caninum, but not to anti-Toxoplasma gondii serum in an immunohistochemical test.
authors.affiliation: Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803.
authors.forename: J D
authors.initials: JD
authors.lastname: Hoskins
authors.forename: M M
authors.initials: MM
authors.lastname: Bunge
authors.forename: J P
authors.initials: JP
authors.lastname: Dubey
authors.forename: D E
authors.initials: DE
authors.lastname: Duncan
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D008297:Male; D011528:Protozoan Infections / Q000473:pathology; D011529:Protozoan Infections, Animal