Transformation of sitosterol to androsta-1, 4-diene-3, 17-dione by immobilized Mycobacterium cells.
Transformation of sitosterol to androsta-1, 4-diene-3, 17-dione was studied with Mycobacterium cells entrapped in various polymeric matrices. Of the three supports viz. alginate, carageenan, agarose and polyacrylamide, studied, the polyacrylamide immobilized cells showed optimum catalytic stability and reusability.
Roy
P K
PK
Fermentation Technology Division, Central Drug Research Institute, Lucknow, India.
Khan
A W
AW
Basu
S K
SK
D000730:Androstadienes / Q000378:metabolism*; D001711:Biotransformation; D007700:Kinetics; D009161:Mycobacterium / Q000378:metabolism*; D012855:Sitosterols / Q000378:metabolism*
D000730:Androstadienes; D012855:Sitosterols; C006573:1,4-androstadiene-3,17-dione; C025473:gamma-sitosterol