title: [Nocturnal oxygen saturation in patients with coronary heart disease--dependent on degree of left ventricular functional impairment].
abstract: It is assumed, that patients with coronary heart disease (CHD) more often suffer from sleep related disorders of breathing than healthy subjects. A relation to an impaired left ventricular performance is discussed. In 40 CHD-patients and 30 cardio-respiratory healthy controls we therefore measured arterial oxygenation during sleep by means of pulse-oximetry. Our results show a marked increase in the frequency of nocturnal oxygen-desaturations along with the degree of impaired left ventricular function independent of a special sleep apnea risk. In case of cardiac insufficiency at rest cyclical oxygen-desaturations were observed ten times as often as in the healthy controls. A central disturbance of the respiratory control, which leads to periodic breathing (type Cheyne-Stokes) has to be discussed. Because of the general high risk of CHD-patients concerning the development of nocturnal complications of their disease, sleep-related disturbances of ventilation have to be detected early by means of routinely applied screening-methods.
authors.affiliation: Medizinische Klinik und Poliklinik, Abteilung für Pneumologie und Allergologie, Ruhr-Universität Bochum.
authors.forename: K
authors.initials: K
authors.lastname: Rasche
authors.forename: H P
authors.initials: HP
authors.lastname: Hoffarth
authors.forename: W
authors.initials: W
authors.lastname: Marek
authors.forename: W
authors.initials: W
authors.lastname: Reier
authors.forename: S
authors.initials: S
authors.lastname: von Dryander
mesh_terms: D000328:Adult; D003327:Coronary Disease / Q000097:blood / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010092:Oximetry; D010100:Oxygen / Q000097:blood*; D012891:Sleep Apnea Syndromes / Q000503:physiopathology; D016277:Ventricular Function, Left / Q000502:physiology*
chemical_list: D010100:Oxygen
vernacular_title: Nächtliche Sauerstoffsättigung bei Patienten mit koronarerHerzkrankheit--Abhängigkeit vom Grad der linksventrikulären Funktionsstörung.