[Functioning of implantable catheters of intraperitoneal chemotherapy].
Intraperitoneal chemotherapy with a totally implantable catheter was performed in 42 patients with advanced ovarian cancer who received 178 courses of chemotherapy administered in 2 l of solution. Major complication was inflow obstruction due to fibrosis around the catheter observed in 10 patients, 23.8% of the cases. Other complications were: leakage 3 (7.1%), pain 3 (7.2%), infection 3 (7.1%) and rectal perforation 1 (2.4%). Overall, these complications occurred in 15 patients (35.7%) and were the cause of treatment interruption in 7 (16.7%). Outflow obstruction which occurred in 23 patients (54.8%), did not create discomfort and could not be considered as a complication. Despite the problems, intraperitoneal chemotherapy with a totally implantable catheter appeared feasible in at least 80% of the patients.
de Gramont
A
A
GERCOD, Hôpital Saint-Antoine, Paris.
Marpeau
L
L
Demuynck
B
B
Gonzalez-Canali
G
G
Pigné
A
A
Herbulot
P
P
Lagadec
B
B
Cady
J
J
Couturier
J Y
JY
Delfau
S
S
D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D002404:Catheterization / Q000009:adverse effects; D002408:Catheters, Indwelling; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000188:drug therapy*
D000970:Antineoplastic Agents
Fonctionnement des cathéters implantables de chimiothérapie intrapéritonéale.