Histological differentiation in fetal organ-cultured and human cataractous eye lenses.
Swine fetal organ-cultured lenses were studied histoautoradiographically and histologically, and human cataractous lenses were examined histologically to investigate the continuous differentiation of epithelial cells into fiber cells in the lens equatorial region. Both lens groups studied presented abnormal differentiation: the equatorial epithelium proliferates; nucleus-containing cortical fibers turn into bladder cells (of Wedl), and the formation of new cortical fibers stops.
Veromann
S
S
Institute of General and Molecular Pathology, Tartu University, Estonia, USSR.
D000818:Animals; D001345:Autoradiography; D002386:Cataract / Q000473:pathology*; D002454:Cell Differentiation; D002455:Cell Division; D004847:Epithelial Cells; D004848:Epithelium / Q000473:pathology; D005333:Fetus; D006801:Humans; D007908:Lens, Crystalline / Q000166:cytology / Q000473:pathology*; D009924:Organ Culture Techniques; D013552:Swine; D001743:Urinary Bladder / Q000473:pathology