[Study of antimutagenic properties of bio-ginseng in mammalian cells in vitro and in vivo].
The impact was studied of bio-ginseng produced from ginseng callus cells on the rate of chromosome rearrangements in Chinese hamster cells and in continuous tumor cells of mice (Ehrlich strain). Bio-ginseng reduced rate of spontaneous SCE as well as the level of mitomycin C-induced chromosome aberrations in Chinese hamster cells. It protected ascitic tumor cells (Ehrlich strain) against the mutagen action of urea nitrosomethyl.
Umnova
N V
NV
Michurina
T L
TL
Smirnova
N I
NI
Aleksandrova
I V
IV
Poroshenko
G G
GG
D000818:Animals; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D006224:Cricetinae; D003412:Cricetulus; D051379:Mice; D016296:Mutagenesis / Q000187:drug effects*; D005894:Panax; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D012854:Sister Chromatid Exchange; D014407:Tumor Cells, Cultured
D010936:Plant Extracts
Izuchenie antimutagennykh svoĭstv biozhen'sheniia na kletkakh mlekopitaiushchikh in vitro i in vivo.