title: A case of malignant hypertension and scleroderma after cosmetic surgery.
abstract: A 44-year-old woman with scleroderma-like skin lesions and malignant hypertension following mammoplasty is reported. Sclerotic change is an unusual finding for ordinary finding progressive systemic sclerosis. On admission, she had severe high-renin hypertension and progressive renal failure, suggesting scleroderma renal crisis. With intensive treatment for hypertension including angiotensin-converting enzyme inhibitor, the blood pressure was well controlled. It was then suggested that she had malignant hypertension due to scleroderma after silicone injection, or the so-called human adjuvant disease after cosmetic surgery.
authors.affiliation: Fourth Department of Internal Medicine, Faculty of Medicine, University of Tokyo, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Hitoshi
authors.forename: Y
authors.initials: Y
authors.lastname: Ito
authors.forename: K
authors.initials: K
authors.lastname: Takehara
authors.forename: T
authors.initials: T
authors.lastname: Fujita
authors.forename: E
authors.initials: E
authors.lastname: Ogata
mesh_terms: D000276:Adjuvants, Immunologic; D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001327:Autoimmune Diseases / Q000235:genetics; D001940:Breast / Q000601:surgery*; D005260:Female; D006801:Humans; D006974:Hypertension, Malignant / Q000188:drug therapy / Q000209:etiology*; D007676:Kidney Failure, Chronic / Q000209:etiology; D019736:Prostheses and Implants; D012595:Scleroderma, Systemic / Q000209:etiology*; D012828:Silicones / Q000009:adverse effects*; D013518:Surgery, Plastic / Q000009:adverse effects*
chemical_list: D000276:Adjuvants, Immunologic; D000959:Antihypertensive Agents; D012828:Silicones