[Cortical-cell thymomas with predominance of so-called nurse-cells in patients with myasthenia].
30 thymomas in patients with generalized myasthenia studied histologically and immunohistochemically are classified as cortico-cell thymomas (n-15), medullary-cell (n-1), mixed-cell (n-10) and cortical-cell thymomas consisting mainly of thymic "nurse"-cells. Pronounced histological features of thymomas with the predominance of "nurse"-cells allow one to consider them as a special variant of thymic tumours. Production of thymic hormones by tumour cells in combination with the loss of HLA-DR antigen expression may be of importance in the pathogenesis of autoimmunization in patients with myasthenia.
Zaĭrat'iants
O V
OV
Vetshev
P S
PS
Popova
I V
IV
Ippolitov
I Kh
IKh
Voronov
L I
LI
D002452:Cell Count; D006801:Humans; D007150:Immunohistochemistry; D007958:Leukocyte Count; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000150:complications*; D013945:Thymoma / Q000150:complications / Q000473:pathology*; D013953:Thymus Neoplasms / Q000150:complications / Q000473:pathology*
Kortikal'nokletochnye timomy s preobladaniem kletok-"nianek" u bol'nykh miastenieĭ.