title: [A clinical and cytogenetic study of 50 women with Turner's syndrome. Considerations of the problem of pregnancies in these patients. Part 2].
abstract: The results of a study on 50 patients with Turner syndrome, all of them older than 14 years and never treated, are reported. In order to correlate karyotypes and clinical manifestations of the syndrome, we performed a complete physical examination and ultra sonographic tests of the heart, kidneys, uterus and ovaries. We found a better spontaneous growth and sexual maturation in mosaic 45.X/46.XX patients than in patients with 45.X and X structural anomalies. No differences were found in heart and kidney congenital anomalies between groups of patients with different karyotypes. We conclude that the presence of an XX-line has an ameliorating effect on height and gonadal function of patients with Turner syndrome.
authors.affiliation: V Cattedra di Clinica Pediatrica, Università degli Studi di Roma La Sapienza.
authors.forename: P
authors.initials: P
authors.lastname: Vignetti
authors.forename: L
authors.initials: L
authors.lastname: Tarani
authors.forename: C
authors.initials: C
authors.lastname: Cives
authors.forename: L
authors.initials: L
authors.lastname: Bruni
authors.forename: M C
authors.initials: MC
authors.lastname: Tozzi
authors.forename: A M
authors.initials: AM
authors.lastname: Pasquino
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics; D000293:Adolescent; D000328:Adult; D005260:Female; D005838:Genotype; D006801:Humans; D007621:Karyotyping; D009030:Mosaicism / Q000235:genetics; D010641:Phenotype; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology; D014424:Turner Syndrome / Q000175:diagnosis* / Q000453:epidemiology / Q000235:genetics
vernacular_title: Studio clinico e citogenetico di 50 donne con sindrome di Turner. Considerazioni sul problema delle gravidanze in queste pazienti. Seconda comunicazione.