Phospholipase A2--a mediator between proximal and distal effectors of inflammation.
Phospholipase A2 (PLA2) is known to play an important intracellular role in inflammatory processes but does it also perform a vital function extracellularly? Here, W. Pruzanski and P. Vadas marshall the evidence supporting PLA2 as a mediator of inflammation, specifically in linking local and systemic effects.
Pruzanski
W
W
University of Toronto, Canada.
Vadas
P
P
D000818:Animals; D006801:Humans; D007249:Inflammation / Q000503:physiopathology*; D010741:Phospholipases A / Q000502:physiology*; D054467:Phospholipases A2
D010741:Phospholipases A; D054467:Phospholipases A2