[Changes in leucocytic estrogen receptor levels in patients with gynecomastia].
The number of estrogen receptor (ER) in human peripheral leucocytes in 13 men with gynecomastia were measured by radioligand binding method. The results were compared with those of 13 sex-and age-matched healthy subjects. It was found that the number of ER in leucocytes was significantly increased in gynecomastia (Rs of leucocytes were 1054 +/- 254 sites/cell). It suggested that increase of ER levels play an important role in the pathogenesis of gynecomastia.
Zhou
D J
DJ
Department of Endocrinology, Changhai Hospital, Second Military Medical College, Shanghai.
Zhang
J Q
JQ
Qiao
D B
DB
D000328:Adult; D000368:Aged; D004958:Estradiol / Q000097:blood; D006177:Gynecomastia / Q000097:blood*; D006801:Humans; D007962:Leukocytes / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011869:Radioligand Assay; D011960:Receptors, Estrogen / Q000097:blood*; D013739:Testosterone / Q000097:blood
D011960:Receptors, Estrogen; D013739:Testosterone; D004958:Estradiol