Vasopressin levels in infants during the course of aseptic and bacterial meningitis.
We measured urine vasopressin (VP) once daily on days 1 through 3 in 18 patients hospitalized with meningitis. Urine VP values were 215 +/- 100, 116 +/- 44, and 69 +/- 23 pg/mL on days 1 through 3, respectively, for children with bacterial meningitis and 34 +/- 14, 20 +/- 4, and 15 +/- 4 pg/mL for those with aseptic meningitis. Urinary VP levels of infants with bacterial meningitis were significantly greater than those of healthy ambulatory subjects (n = 18) on all three study days; VP values of infants with bacterial meningitis were also greater than those of infants with aseptic meningitis on study days 2 and 3. The VP levels for the subjects with aseptic meningitis were significantly greater than those of the controls on day 1 only. None of the infants exhibited the clinical syndrome of inappropriate antidiuretic hormone secretion.
Padilla
G
G
Department of Pediatrics, UCLA School of Medicine.
Ervin
M G
MG
Ross
M G
MG
Leake
R D
RD
D001424:Bacterial Infections / Q000097:blood / Q000652:urine*; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000209:etiology; D007223:Infant; D008581:Meningitis / Q000097:blood / Q000652:urine*; D008582:Meningitis, Aseptic / Q000097:blood / Q000652:urine*; D009994:Osmolar Concentration; D012307:Risk Factors; D012964:Sodium / Q000097:blood / Q000652:urine; D013997:Time Factors; D014667:Vasopressins / Q000652:urine*
D014667:Vasopressins; D012964:Sodium