Wegener's granulomatosis presenting as diffuse pulmonary hemorrhage.
A 35-year-old woman experienced diffuse intraalveolar haemorrhage with respiratory distress and acute renal failure. Renal histology and evolution confirmed Wegener's granulomatosis. Early use of immunosuppressive drugs allowed weaning from mechanical ventilation and temporary improvement of the renal failure. A review of the literature emphasizes the rarity of alveolar hemorrhage as an initial symptom of Wegener's granulomatosis and the necessity of aggressive management.
Misset
B
B
Service de Réanimation Médicochirurgicale, Hôpital Broussais, Paris, France.
Glotz
D
D
Escudier
B
B
Nochy
D
D
Bosq
J
J
Gilles
E
E
Leclercq
B
B
Nitenberg
G
G
D000328:Adult; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications*; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D008171:Lung Diseases / Q000209:etiology*; D011650:Pulmonary Alveoli