Statistical analyses of enzyme inhibitor kinetics: a hierarchical model-dependent approach.
Inference of the nature of an enzyme inhibitor and calculations of inhibitor constants from linear plots are prone to be unreliable when experimental error is significant. This may be minimised by a method of statistical analysis using nonlinear regression methods and modelling using the variance ratio test of a hierarchy of models of inhibitor behaviour.
Tsai
H H
HH
Department of Medicine, University of Liverpool, United Kingdom.
D003198:Computer Simulation; D004791:Enzyme Inhibitors / Q000378:metabolism*; D007700:Kinetics; D016018:Least-Squares Analysis; D015233:Models, Statistical; D012044:Regression Analysis
D004791:Enzyme Inhibitors