Effects of anti-infectious agents on polymorphonuclear neutrophils.
Polymorphonuclear neutrophils play a crucial role in host defences against infectious diseases. New trends in anti-infectious therapy require knowledge of the possible interactions between the drugs and the natural defence system. This overview summarizes some of the in vitro data on the effects of anti-infectious agents on neutrophils. The relevance for the clinical situation is discussed.
Labro
M T
MT
INSERM U. 294, Centre Hospitalier Universitaire X. Bichat, Paris, France.
el Benna
J
J
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002511:Cephalosporins / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D009504:Neutrophils / Q000187:drug effects* / Q000502:physiology
D000900:Anti-Bacterial Agents; D002511:Cephalosporins