title: Preliminary X-ray crystallographic investigation of human parvovirus B19.
abstract: Crystals that diffract X rays to at least 8 A resolution have been grown from human B19 parvovirus empty capsids. These particles consist of VP-2 derived from a baculovirus expression system. This is possibly the first time that a self-assembled empty viral capsid, grown in other than normal host cells, has been crystallized. Partial X-ray diffraction data have been collected using synchrotron radiation. The space group is P2(1)3 with a = 362 A. The particle position in the crystal cell is given, at least roughly, from packing considerations.
authors.affiliation: Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907.
authors.forename: M
authors.initials: M
authors.lastname: Agbandje
authors.forename: R
authors.initials: R
authors.lastname: McKenna
authors.forename: M G
authors.initials: MG
authors.lastname: Rossmann
authors.forename: S
authors.initials: S
authors.lastname: Kajigaya
authors.forename: N S
authors.initials: NS
authors.lastname: Young
mesh_terms: D000818:Animals; D002460:Cell Line; D005814:Genes, Viral; D006801:Humans; D007313:Insecta; D008854:Microscopy, Electron; D010321:Parvoviridae / Q000235:genetics / Q000648:ultrastructure*; D010957:Plasmids; D012333:RNA, Messenger / Q000235:genetics; D014961:X-Ray Diffraction / Q000379:methods
chemical_list: D012333:RNA, Messenger