Awakening and recovery of simple cognitive and psychomotor functions 2 h after anaesthesia for day-case surgery--total intravenous anaesthesia with propofol-alfentanil versus thiopentone-alfentanil.
Fifty-seven patients undergoing minor out-patient gynaecological procedures were allocated to one of two total intravenous anaesthesia regimes: propofol and alfentanil or thiopentone and alfentanil. Diazepam was given orally as premedication. To assess objectively the quality of recovery, the patients underwent a number of tests pre-operatively and two hours post-operatively. The time to opening of eyes and orientation was equal in both groups, as was the recovery of the tested cognitive and psychomotor functions after 2 h, when the score in both groups had returned to baseline. We conclude that the use of propofol instead of thiopentone for shorter surgical procedures gives no advantage as regards length of stay in hospital.
Nielsen
J
J
Department of Anaesthesia, Central Hospital Hillerød, Denmark.
Jenstrup
M
M
Gerdes
N U
NU
Rasmussen
L S
LS
Fruergaard
K
K
Wiberg-Jørgensen
F
F
D000293:Adolescent; D000328:Adult; D015760:Alfentanil / Q000008:administration & dosage / Q000494:pharmacology*; D000556:Ambulatory Surgical Procedures; D000762:Anesthesia Recovery Period; D000771:Anesthesia, Intravenous; D001143:Arousal / Q000187:drug effects; D001288:Attention / Q000187:drug effects; D003071:Cognition / Q000187:drug effects*; D003243:Consciousness / Q000187:drug effects*; D005260:Female; D006801:Humans; D007902:Length of Stay; D008568:Memory / Q000187:drug effects; D008570:Memory, Short-Term / Q000187:drug effects; D008875:Middle Aged; D009048:Motor Skills / Q000187:drug effects; D015742:Propofol / Q000008:administration & dosage / Q000494:pharmacology*; D011597:Psychomotor Performance / Q000187:drug effects*; D013874:Thiopental / Q000008:administration & dosage / Q000494:pharmacology*; D013997:Time Factors
D015760:Alfentanil; D013874:Thiopental; D015742:Propofol