title: Total and split renal function assessed by ultrasound Doppler techniques.
abstract: We evaluated total and split renal functions from the pattern for renal arterial blood flow detected by ultrasound Doppler in healthy subjects and patients with varying degrees of renal function and disorders other than renovascular hypertension or severe aortic valvular disease. A renal-time pulsed ultrasonic echo-Doppler device at 2.5 MHz was used with a translumbar approach. The ratio of peak diastolic (D) to systolic (S) velocity correlated well with both p-aminohippurate clearance and creatinine clearance. Acceleration time was correlated with the clearance of neither compound. To evaluate the clinical usefulness of ultrasound Doppler in the assessment of split renal function, we compared the D/S ratio with the renal function obtained by radionuclide methods for individuals. The split renal glomerular filtration rate, calculated by a method which makes use of the early renal uptake of 99mTc-diethylenetriam-inepentaacetic acid, correlated well with the D/S ratio. These results indicate that the ultrasonic measurement of renal arterial blood flow by the pulsed Doppler method should be useful for assessment of total and split renal functions.
authors.affiliation: Second Department of Internal Medicine, Kagawa Medical School, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yura
authors.forename: Y
authors.initials: Y
authors.lastname: Takamitsu
authors.forename: S
authors.initials: S
authors.lastname: Yuasa
authors.forename: S
authors.initials: S
authors.lastname: Miki
authors.forename: N
authors.initials: N
authors.lastname: Takahashi
authors.forename: H
authors.initials: H
authors.lastname: Bandai
authors.forename: T
authors.initials: T
authors.lastname: Sumikura
authors.forename: K
authors.initials: K
authors.lastname: Uchida
authors.forename: T
authors.initials: T
authors.lastname: Tamai
authors.forename: H
authors.initials: H
authors.lastname: Matsuo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging / Q000502:physiology* / Q000503:physiopathology; D007674:Kidney Diseases / Q000000981:diagnostic imaging* / Q000503:physiopathology; D007677:Kidney Function Tests; D008297:Male; D008657:Metabolic Clearance Rate / Q000502:physiology; D008875:Middle Aged; D011877:Radionuclide Imaging; D012016:Reference Values; D012077:Renal Artery / Q000502:physiology; D012079:Renal Circulation / Q000502:physiology*; D014463:Ultrasonography