Uterine and fetal Doppler flow changes after intravaginal prostaglandin E2 therapy for cervical ripening.
Nineteen patients received prostaglandin E2 as a 2.5 mg gel (seven cases), 3.3 mg chip (five cases), or 10 mg controlled-release pessary (seven cases) for preinduction cervical ripening. Blood flow velocities did not change significantly for the uterine arcuate artery, fetal aorta, and umbilical artery circulations after any of the treatments. In no case did systolic/diastolic ratios consistently elevate above baseline values.
Rayburn
W F
WF
Department of Obstetrics and Gynecology, University of Nebraska College of Medicine, Omaha.
Anderson
J C
JC
Smith
C V
CV
Appel
L L
LL
D001775:Blood Circulation / Q000187:drug effects*; D002584:Cervix Uteri / Q000187:drug effects*; D015232:Dinoprostone / Q000627:therapeutic use*; D005260:Female; D005333:Fetus / Q000502:physiology*; D006801:Humans; D007751:Labor, Induced / Q000379:methods*; D011247:Pregnancy; D012039:Regional Blood Flow / Q000187:drug effects; D014599:Uterus / Q000098:blood supply*
D015232:Dinoprostone