Endogenous N-nitrosation and cancer of the biliary tract.
Evidence is presented that N-nitroso compounds occur in bile from patients who have undergone surgery for gallstones or had gastrectomy and from unoperated persons. It is unlikely, therefore, that local formation of nitrosamines can account for the excess risk for gallbladder cancer in the first two groups. Gastric formation remains the likeliest hypothesis.
Caygill
C P
CP
Public Health Laboratory Service, Communicable Disease Surveillance Centre, London, UK.
Leach
S A
SA
Fernandez
F
F
Duncan
S
S
Hill
M J
MJ
Massey
R
R
Hall
R
R
D001646:Bile / Q000737:chemistry; D001661:Biliary Tract Neoplasms / Q000139:chemically induced*; D006801:Humans; D009603:Nitroso Compounds / Q000032:analysis / Q000378:metabolism / Q000633:toxicity*
D009603:Nitroso Compounds