Neurocysticercosis: neurologic, pathogenic, diagnostic and therapeutic aspects.
Worldwide neurocysticercosis is the most common parasitic infection of the human brain and meninges. Clinical features of the illness vary with the stage of ova infection, but most problems arise when the mature cyst degenerates. Seizures, increased intracranial pressure, and focal neurologic signs then often develop. Computed tomography and magnetic resonance usually demonstrate Cysticercus cellulosae cysts in the brain. A new immunoblot test for antibodies to the cysticercus seems both sensitive and specific. Treatment with praziquantel or albendazole has hastened the disappearance of the cysts on computed tomography and improved clinical symptoms.
Davis
L E
LE
Neurology Service, Department of Veterans Affairs Medical Center, Albuquerque, N. Mex.
Kornfeld
M
M
D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D001927:Brain Diseases / Q000469:parasitology*; D003551:Cysticercosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008578:Meninges / Q000469:parasitology; D011223:Praziquantel / Q000627:therapeutic use; D013621:Taenia / Q000469:parasitology; D014057:Tomography, X-Ray Computed
D011223:Praziquantel; D015766:Albendazole