[Anti-tumor effect of Cetraria laevigata Rassad. polysaccharides].
The anti-tumor effect of Cetraria laevigata polysaccharides has been investigated in mice using sarcoma 180; Ehrlich ascitic tumor, cervical carcinoma u-14 and leukemia L7217. The results show that Cetraria laevigata polysaccharides may inhibit the growth of sarcoma 180, Ehrlich ascitic tumor and cervical carcinoma u-14 in mice at a dose of 200mg/kg ip (1/5 LD50). However, the survival time of leukemia L7217 wasn't prolonged. The reticuloendothelial system phagocytic function in mice was increased at ip doses of 50 mg/kg and 100 mg/kg (1/10 and 1/20 LD50).
Wang
G
G
Jilin Provincial Academy of Traditional Chinese Medicine and Materia, Medica, Changchun.
Li
Y
Y
Wang
B
B
Gao
J
J
Yan
Z
Z
Li
X
X
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic; D005260:Female; D008011:Lichens; D051379:Mice; D009374:Neoplasms, Experimental / Q000188:drug therapy*; D010587:Phagocytosis / Q000187:drug effects; D011134:Polysaccharides / Q000627:therapeutic use*; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy
D000972:Antineoplastic Agents, Phytogenic; D011134:Polysaccharides