A rapid gas chromatography-mass spectrometry method for the determination of urinary 3-methyladenine: application in human subjects.
A rapid gas chromatography-mass spectrometry method, employing immunoaffinity clean-up, has been developed for the measurement of 3-methyladenine in human urine samples. A wide variation in levels of urinary 3-methyladenine was observed, indicating that at least some may be derived from the diet and not be related to endogenous nitrosation and subsequent methylation.
Shuker
D E
DE
International Agency for Research on Cancer, Lyon, France.
Friesen
M D
MD
Garren
L
L
Prévost
V
V
D000225:Adenine / Q000031:analogs & derivatives* / Q000652:urine; D000293:Adolescent; D002846:Chromatography, Affinity; D004938:Esophageal Neoplasms / Q000652:urine; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans
C025946:3-methyladenine; D000225:Adenine