title: Preventive and therapeutic effects of lithium carbonate on acute radiation injury of hemopoietic system in mice.
abstract: The administration of Li2CO3 to female LACA mice for three consecutive days before or after 4Gy whole body gamma-irradiation appeared to have both preventive and therapeutic effects on radiation-induced leucopenia, especially on the depression of CFU-GM. It is effective in small dosage, short course, and even when given 24 hours after irradiation.
authors.affiliation: Research Center of Occupational Medicine, Third Hospital, Beijing Medical University.
authors.forename: X Y
authors.initials: XY
authors.lastname: Ke
authors.forename: Y F
authors.initials: YF
authors.lastname: Wang
authors.forename: T Z
authors.initials: TZ
authors.lastname: Jia
mesh_terms: D000818:Animals; D003114:Colony-Forming Units Assay; D005260:Female; D006410:Hematopoiesis / Q000187:drug effects; D007970:Leukopenia / Q000188:drug therapy / Q000517:prevention & control*; D008094:Lithium / Q000494:pharmacology / Q000627:therapeutic use*; D016651:Lithium Carbonate; D008297:Male; D051379:Mice; D011833:Radiation Injuries, Experimental / Q000188:drug therapy / Q000517:prevention & control*; D014916:Whole-Body Irradiation
chemical_list: D016651:Lithium Carbonate; D008094:Lithium