title: Persistent facial ulcerations with a unique clinical appearance: possible trigeminal trophic syndrome.
abstract: We reported a 53-year-old woman with a persistent facial ulcer which moved gradually from the right marginal portion of the nasal root to the right lateral canthus along the margin of the right lower eyelid. The ulcer healed spontaneously. A similar ulcer developed at the entrance of the right anterior naris. The clinical findings were suggestive of squamous cell carcinoma, deep mycosis, mycobacterial infection, or a related condition. However, no definitive diagnosis could be made from the clinicopathological findings or the laboratory examinations, including bacterial, mycobacterial, and fungal cultures. The characteristic location of the lesion, and course of the disease, however, suggested the diagnosis of trigeminal trophic syndrome.
authors.affiliation: Department of Dermatology, Faculty of Medicine, Tottori University, Yonago, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Inoue
authors.forename: M
authors.initials: M
authors.lastname: Mihara
authors.forename: H
authors.initials: H
authors.lastname: Nakayama
authors.forename: S
authors.initials: S
authors.lastname: Shimao
authors.forename: Y
authors.initials: Y
authors.lastname: Shimizu
mesh_terms: D002908:Chronic Disease; D003937:Diagnosis, Differential; D005148:Facial Dermatoses / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012008:Recurrence; D012883:Skin Ulcer / Q000473:pathology*; D013577:Syndrome; D061221:Trigeminal Nerve Injuries