title: Replication origins, factors and attachment sites.
abstract: The initiation of eukaryotic DNA synthesis occurs at specific sites determined by both cis- and trans-acting elements. Here I review advances in the characterization of yeast origins, origin-binding proteins and the relationship of DNA replication to nuclear substructure in yeast.
authors.affiliation: Swiss Institute for Experimental Cancer Research, Lausanne.
authors.forename: S M
authors.initials: SM
authors.lastname: Gasser
mesh_terms: D000818:Animals; D001483:Base Sequence; D001665:Binding Sites; D004247:DNA / Q000235:genetics*; D004261:DNA Replication; D004268:DNA-Binding Proteins; D008957:Models, Genetic; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation
chemical_list: D004268:DNA-Binding Proteins; D004247:DNA