Hepatitis C virus infection is the major cause of severe liver disease in India.
The present study describes the status of hepatitis C virus infection in 167 patients with severe forms of liver diseases in India. The anti-HCV positivity rate was recorded as 43%, 47%, and 42% in patients with FHF, SAHF, and CAH respectively. HBV and HCV coinfection was recorded in 28% of FHF, 43% of SAHF and 75% of the CAH cases. Superinfection of HCV in HBsAg carriers was recorded in the 54% cases of FHF, 60% of SAHF and 42% of the CAH. None of these 167 patients was positive of HAV-IgM. Further, 27.7% of FHF, 26.4% of SAHF and 15.2% of CAH cases were neither HBV nor HCV markers positive. These can be labelled as non-A, non-B and non-C infections.
Tandon
B N
BN
Department of Gastroenterology, All-India Institute of Medical Sciences, New Delhi.
Irshad
M
M
Acharya
S K
SK
Joshi
Y K
YK
D006509:Hepatitis B / Q000150:complications; D006526:Hepatitis C / Q000150:complications / Q000453:epidemiology*; D006521:Hepatitis, Chronic / Q000382:microbiology; D006801:Humans; D007194:India / Q000453:epidemiology; D008107:Liver Diseases / Q000382:microbiology*; D015163:Superinfection / Q000453:epidemiology