Comparison between Bricanyl Turbuhaler and Ventolin metered dose inhaler in the treatment of exercise-induced asthma in adults.
The aim of the present study was to compare the effect of Bricanyl Turbuhaler (0.5 mg x 1 terbutaline) with the effect of albuterol metered dose inhaler (0.1 mg x 2 albuterol) in patients with reproducible bronchoconstriction. The study was performed as a double-blind placebo-controlled trial in sixteen asthmatic adults. Bronchoconstriction was induced by steady state running on a treadmill. Both 0.5 mg terbutaline and 0.2 mg albuterol have good bronchodilating effects in patients with exercise-induced asthma. There was, however, a faster onset of action after albuterol. The clinical value of this observed difference is uncertain.
Vilsvik
J
J
Dept. of Pulmonary Diseases, Regional Hospital, University of Trondheim, Norway.
Schaanning
J
J
Ståhl
E
E
Holthe
S
S
D000281:Administration, Intranasal; D000293:Adolescent; D000328:Adult; D000420:Albuterol / Q000008:administration & dosage*; D001250:Asthma, Exercise-Induced / Q000188:drug therapy*; D004311:Double-Blind Method; D006339:Heart Rate; D006801:Humans; D008875:Middle Aged; D009330:Nebulizers and Vaporizers / Q000706:statistics & numerical data*; D010366:Peak Expiratory Flow Rate; D010919:Placebos; D013726:Terbutaline / Q000008:administration & dosage*
D010919:Placebos; D013726:Terbutaline; D000420:Albuterol