Gemfibrozil-induced myopathy.
Drug-induced myopathy has been reported with use of lovastatin, nicotinic acid, and clofibrate. A particularly severe form, often accompanied by rhabdomyolysis, has been reported with the use of lovastatin and gemfibrozil; however, as far as we know, no case has been documented with use of gemfibrozil alone. Herein, we report the first case (to our knowledge of gemfibrozil-induced myopathy, confirmed by drug rechallenge.
Magarian
G J
GJ
Division of General Internal Medicine, Oregon Health Sciences University, Portland.
Lucas
L M
LM
Colley
C
C
D002994:Clofibrate / Q000009:adverse effects; D004359:Drug Therapy, Combination; D015248:Gemfibrozil / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D015228:Hypertriglyceridemia / Q000188:drug therapy; D008148:Lovastatin / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000139:chemically induced*
D008148:Lovastatin; D002994:Clofibrate; D015248:Gemfibrozil