title: Hypocalcemic focal seizures in a one-month-old infant of a mother with a low circulating level of vitamin D.
abstract: We present a case of a one-month-old infant with hypocalcemia and rickets, with symptoms of focal seizures. The ictal EEG showed left occipital spikes spreading over all of the left hemisphere. From the laboratory studies, we concluded that a low maternal circulating level of vitamin D would cause infantile hypocalcemia and rickets, while immature renal response to parathyroid hormone and transient hypoparathyroidism in infancy would induce hyperphosphatemia. Hypocalcemia may be an important factor in the cause of focal seizures which start even after the age of one month. Further, investigation of maternal vitamin D levels should be done in infantile hypocalcemia.
authors.affiliation: Department of Pediatrics, Asahikawa Medical College, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Oki
authors.forename: M
authors.initials: M
authors.lastname: Takedatsu
authors.forename: J
authors.initials: J
authors.lastname: Itoh
authors.forename: K
authors.initials: K
authors.lastname: Yano
authors.forename: K
authors.initials: K
authors.lastname: Cho
authors.forename: A
authors.initials: A
authors.lastname: Okuno
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D006996:Hypocalcemia / Q000097:blood / Q000150:complications*; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood*; D012640:Seizures / Q000209:etiology*; D014808:Vitamin D Deficiency / Q000097:blood / Q000150:complications*