title: Damage to the cytoplasmic membrane and cell death caused by dodine (dodecylguanidine monoacetate) in Pseudomonas syringae ATCC 12271.
abstract: Treatment of Pseudomonas syringae cells with low concentrations of the fungicide dodecylguanidine monoacetate (dodine) resulted in cell death and leakage of K+, UV-absorbing materials, and ribose-containing molecules. The results suggest that dodine causes gross and extensive damage to the cytoplasmic membrane, which is probably implicated in the death of cells.
authors.affiliation: Instituto Nacional de Investigação Científica, Centro de Citologia Experimental da Universidade do Porto, Portugal.
authors.forename: J P
authors.initials: JP
authors.lastname: Cabral
mesh_terms: D002470:Cell Survival / Q000187:drug effects*; D004396:Coloring Agents; D003593:Cytoplasm / Q000187:drug effects*; D005659:Fungicides, Industrial / Q000633:toxicity*; D006146:Guanidines / Q000633:toxicity*; D008566:Membranes / Q000187:drug effects / Q000378:metabolism; D011188:Potassium / Q000378:metabolism; D011549:Pseudomonas / Q000187:drug effects*; D012266:Ribose / Q000378:metabolism; D014466:Ultraviolet Rays
chemical_list: D004396:Coloring Agents; D005659:Fungicides, Industrial; D006146:Guanidines; C006921:dodine; D012266:Ribose; D011188:Potassium