title: [Reevaluation of the unilateral pulmonary artery occlusion test--hemodynamics after lobectomy and pneumonectomy for lung cancer].
abstract: After lobectomy, it is recognized that functional as well as absolute reduction occurs in residual lobes of the operated side. So whether lobectomy is indicated or not is determined by the same criteria as those for pneumonectomy, namely, by the unilateral pulmonary artery occlusion (UPAO) test. However, is it really appropriate to use the same criteria for both lobectomy and pneumonectomy? To answer to this question, in patients with lung cancer we compared the hemodynamics after lobectomy (13 cases) and pneumonectomy (14 cases) with that at the UPAO test. After pneumonectomy, the mean pulmonary arterial wedge pressure (mPWP) was significantly lower than that on the preoperative day and at the test. It seemed that hypovolemic change occurred in the hemodynamics after pneumonectomy. After pneumonectomy, the pulmonary arteriolar resistance index (PARI) was significantly higher than the preoperative value. It was the same as that as at the time of the UPAO test. The total pulmonary vascular resistance index (TPVRI) at the time of the test was significantly higher than the preoperative value, but the TPVRI after pneumonectomy was not significantly higher. The TPVRI tended to decrease after pneumonectomy, compared to the value predicated by the test. These results indicated that some of the cases judged inoperable on the basis of the UPAO test might be operable. On the day of lobectomy, the PARI was significantly higher than the preoperative value, but significantly lower than that at the time of the test. The cardiac index (CI) was significantly higher and the mPWP was significantly lower than each preoperative value.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: First Department of Surgery, Fukushima Medical College, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Ohishi
authors.forename: K
authors.initials: K
authors.lastname: Yanai
authors.forename: T
authors.initials: T
authors.lastname: Saioth
authors.forename: R
authors.initials: R
authors.lastname: Kanno
authors.forename: M
authors.initials: M
authors.lastname: Kogure
authors.forename: T
authors.initials: T
authors.lastname: Takeshige
authors.forename: Y
authors.initials: Y
authors.lastname: Teranishi
authors.forename: A
authors.initials: A
authors.lastname: Usuba
authors.forename: H
authors.initials: H
authors.lastname: Inoue
authors.forename: R
authors.initials: R
authors.lastname: Motoki
mesh_terms: D000368:Aged; D003250:Constriction; D005069:Evaluation Studies as Topic; D006439:Hemodynamics; D006801:Humans; D008175:Lung Neoplasms / Q000503:physiopathology / Q000601:surgery*; D008875:Middle Aged; D011013:Pneumonectomy; D011651:Pulmonary Artery / Q000503:physiopathology*; D011652:Pulmonary Circulation