title: Persorption of raw starch: a cause of senile dementia?
abstract: Intact starch granules in food can pass through the intestinal wall and enter the circulation. They remain intact if they have not been cooked for long enough in the presence of water. Some of these granules embolise arterioles and capillaries. In most organs the collateral circulation suffices for continued function. In the brain, however, neurones may be lost. Over many decades the neuronal loss could be of clinical importance. To test this hypothesis, there is a need to examine brains for the presence of embolised starch granules. Examining tissues polariscopically clearly distinguishes starch granules from other objects of similar appearance.
authors.forename: B J
authors.initials: BJ
authors.lastname: Freedman
mesh_terms: D000818:Animals; D003704:Dementia / Q000209:etiology*; D006801:Humans; D007408:Intestinal Absorption; D002542:Intracranial Embolism and Thrombosis / Q000209:etiology; D008954:Models, Biological; D013213:Starch / Q000009:adverse effects* / Q000097:blood / Q000493:pharmacokinetics
chemical_list: D013213:Starch