title: A within-patient comparison between superovulation with intra-uterine artificial insemination using husband's washed spermatozoa and gamete intrafallopian transfer in unexplained infertility.
abstract: The purpose of this study was to evaluate the success of gamete intrafallopian transfer (GIFT) and superovulation with intra-uterine artificial insemination (S-IUI) in couples with long-term unexplained infertility. Thirty-nine couples were offered three attempts at each treatment. Sixty-three IUI cycles were completed with a pregnancy rate of 1.5% per cycle. Forty-nine GIFT procedures were carried out with a pregnancy rate of 26.5% per cycle. The cumulative conception rate after three cycles of GIFT was 0.56. GIFT appears to offer a far greater chance of pregnancy than S-IUI in unexplained infertility.
authors.affiliation: Academic Department of Obstetrics and Gynaecology, Royal Free Hospital, London, U.K.
authors.forename: C A
authors.initials: CA
authors.lastname: Iffland
authors.forename: W
authors.initials: W
authors.lastname: Reid
authors.forename: N
authors.initials: N
authors.lastname: Amso
authors.forename: A G
authors.initials: AG
authors.lastname: Bernard
authors.forename: G
authors.initials: G
authors.lastname: Buckland
authors.forename: R W
authors.initials: RW
authors.lastname: Shaw
mesh_terms: D000328:Adult; D002064:Buserelin / Q000627:therapeutic use; D002996:Clomiphene / Q000627:therapeutic use; D005260:Female; D015181:Gamete Intrafallopian Transfer; D006801:Humans; D007246:Infertility / Q000628:therapy*; D007317:Insemination, Artificial, Homologous; D008297:Male; D008596:Menotropins / Q000627:therapeutic use; D011247:Pregnancy; D013480:Superovulation; D014599:Uterus
chemical_list: D002996:Clomiphene; D008596:Menotropins; D002064:Buserelin