title: Synapses in developing cingulate and hippocampal cortices in undernourished rats.
abstract: Differential patterns of developmental changes were observed between 10 and 150 days of age in numerical densities of ethanolic-phosphotungstic acid stained synapses in the molecular layer of cingulate cortex (area 29 c,d) and hippocampus (CA1)-dentate region in rat. Chronic caloric undernutrition commencing prenatally caused considerable reduction of synaptic densities up to 45 days of age in both the cortices, but showed opposite trends subsequently; the density attained was higher than control in the cingulate area, but lower than control in hippocampus-dentate area. Post-weaning rehabilitatory nutrition resulted in a reduced deviation from normal in the cingulate area but not in the hippocampus-dentate area.
authors.affiliation: Department of Neurophysiology, National Institute of Mental Health and Neurosciences, Bangalore, India.
authors.forename: K D
authors.initials: KD
authors.lastname: Murthy
authors.forename: T
authors.initials: T
authors.lastname: Desiraju
mesh_terms: D000375:Aging; D000818:Animals; D006179:Gyrus Cinguli / Q000254:growth & development*; D006624:Hippocampus / Q000254:growth & development*; D008297:Male; D009748:Nutrition Disorders / Q000503:physiopathology*; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values; D013569:Synapses / Q000502:physiology*