title: [Exudative reaction after implantation of an artificial lens].
abstract: Results of clinical observation over post-operative period and degree of exsudative reaction in 240 patients (262 eyes) with implantation of intraocular lenses are analysed. Three types of postoperative course are distinguished: a reactive, postoperative with early exsudative reaction and postoperative with late exsudative reaction. Immunologic investigations (determination of percentage and absolute amount of T-lymphocytes in peripheral blood, reaction of blast-transformation of lymphocytes on phytohemagglutinin and on antigens of the lens, the choroid and the retina) performed in 184 patients with artiphakia allowed to make a conclusion that postoperative course with late exsudative reaction is dependent on preliminary sensibilization of the body to proteins of eye tissues and has immune nature. The treatment with indometacin proved to be effective and prevented development of late exsudative reaction in 40 patients with implantation of intraocular lenses.
authors.affiliation: Medizinische Hochschule Varna, Bulgarien.
authors.forename: D
authors.initials: D
authors.lastname: Georgiew
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D005549:Foreign-Body Reaction / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D007213:Indomethacin / Q000008:administration & dosage; D007910:Lenses, Intraocular; D007958:Leukocyte Count / Q000187:drug effects; D009883:Ophthalmic Solutions; D011183:Postoperative Complications / Q000188:drug therapy / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D009883:Ophthalmic Solutions; D007213:Indomethacin
vernacular_title: Exsudative Reaktion nach Implantation einer künstlichen Linse.