Mode of action of netzahualcoyone.
The activity of netzahualcoyone on Bacillus subtilis and Escherichia coli was studied. The product inhibited the respiration of intact cells of B. subtilis but had no effect on the respiration of E. coli. However, when preparations of sonically disrupted cells were examined, inhibitory activity on both bacteria was observed.
Moujir
L
L
Departamento de Microbiología y Biología Celular, Universidad de La Laguna, Canary Islands, Spain.
Gutiérrez-Navarro
A M
AM
González
A G
AG
Ravelo
A G
AG
Luis
J G
JG
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects / Q000502:physiology / Q000648:ultrastructure; D002462:Cell Membrane / Q000378:metabolism; D002463:Cell Membrane Permeability / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects / Q000502:physiology / Q000648:ultrastructure; D009243:NAD / Q000378:metabolism; D010084:Oxidation-Reduction; D010101:Oxygen Consumption / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000502:physiology / Q000648:ultrastructure; D014315:Triterpenes / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D010936:Plant Extracts; D014315:Triterpenes; D009243:NAD; C068219:netzahualcoyone