[Giant-cell arteritis: the clinico-biological manifestations and the complications secondary to steroid treatment].
The analysed clinico-biological manifestations, evolutive course and treatment of 30 patients with GCA are presented. The most frequent symptoms were fever and headache. 33% of patients had FOD criteria. 26% had various visual alterations. All patients were initially treated with steroids. Of the 26 patients followed up, 21 (81.7%) experienced some sort of complication: Cushing iatrogenic, osteoporosis, vertebrae collapse, aseptic necrosis of the femur head, arterial hypertension, diabetes mellitus, hyperlipidemia, steroid myopathy. 6 patients were treated with cyclophosphamide, following severe complications secondary to steroid therapy, and all of them had a good clinical evolution.
de la Casa Monje
R
R
Servicio de Medicina Interna, Hospital La Paz, Universidad Autónoma de Madrid.
Barbado Hernández
F J
FJ
Peña Sánchez de Rivera
J M
JM
Domínguez Castellano
A
A
Sendino Revuelta
A
A
González-Anglada
I
I
Vázquez Rodríguez
J J
JJ
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000009:adverse effects*; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D005260:Female; D013700:Giant Cell Arteritis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D013699:Temporal Arteries / Q000473:pathology; D013997:Time Factors
D000305:Adrenal Cortex Hormones
Arteritis de células gigantes: manifestaciones clínico-biológicas y complicaciones secundarias al tratamiento esteroideo.