Idiopathic gastroparesis in patients with unexplained nausea and vomiting.
Nausea and vomiting are symptoms sometimes associated with motor dysfunction. We compared a group of young patients suffering from chronic nausea and/or vomiting and normal upper gastrointestinal x-ray series with a control group. The members of both groups underwent isotopic examinations of their stomachs. The aim of the study was to find a simple method of checking the stomach and proving a motor dysfunction in a group of patients with chronic, inexplicable nausea and vomiting. Patients and controls fasted for at least 6 hr were given 0.5 mCI of [99mTc] diethylene triaminopentaacetic acid orally in 150 cc milk with 50 g cornflakes. A time-activity curve was obtained and radioactivity over the stomach was recorded exponentially. The parameter of the T1/2 emptying time was used. In normal controls T1/2 emptying time ranged from 18 to 26 min. Twenty-five symptomatic patients were examined, three of whom achieved normal values, but 22 patients showed pathologic results ranging from 36 to 184 min. In patients with chronic nausea and/or vomiting an isotopic examination of the stomach may provide a simple and rapid diagnostic method of evaluation.
Wengrower
D
D
Department of Gastroenterology, Hadassah University Hospital, Hebrew University, Jerusalem, Israel.
Zaltzman
S
S
Karmeli
F
F
Goldin
E
E
D000328:Adult; D005260:Female; D005502:Food; D005746:Gastric Emptying / Q000502:physiology*; D005769:Gastrointestinal Motility / Q000502:physiology; D006801:Humans; D008297:Male; D009325:Nausea / Q000209:etiology*; D011877:Radionuclide Imaging; D013270:Stomach / Q000000981:diagnostic imaging; D013272:Stomach Diseases / Q000150:complications* / Q000503:physiopathology; D016284:Technetium Tc 99m Pentetate; D013997:Time Factors; D014839:Vomiting / Q000209:etiology*
D016284:Technetium Tc 99m Pentetate