title: [Effect of betaxolol and timolol on visual fields in glaucoma patients].
abstract: In a prospective, randomized, double-masked study, primary open-angle glaucoma patients were treated twice daily with either betaxolol 0.5% or timolol 0.5%. Patients received a pretreatment baseline examination following a 2 week washout period; they were then examined after 3 and 6 months of treatment. Each examination included visual field measurements with an Octopus automated perimeter and intraocular pressure measurement. The visual fields of the betaxolol group showed on the average a pronounced tendency toward improvement (MD decrease of 2.05 dB); visual fields in the timolol group showed a slight tendency toward improvement (MD decrease of 1.56 dB). The difference between these 2 trends after 6 months was statistically not significant (p greater than or equal to 0.05, U-test). Both drugs lowered intraocular pressure, there was no significant difference between the two drugs (p greater than or equal to 0.05, U-test).
authors.affiliation: Kantonsspital Luzern Augenklinik.
authors.forename: C
authors.initials: C
authors.lastname: Messmer
authors.forename: D
authors.initials: D
authors.lastname: Stümpfig
authors.forename: J
authors.initials: J
authors.lastname: Flammer
mesh_terms: D015784:Betaxolol / Q000008:administration & dosage*; D004311:Double-Blind Method; D005902:Glaucoma, Open-Angle / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D009883:Ophthalmic Solutions; D011446:Prospective Studies; D013999:Timolol / Q000008:administration & dosage*; D014794:Visual Fields / Q000187:drug effects*
chemical_list: D009883:Ophthalmic Solutions; D013999:Timolol; D015784:Betaxolol
vernacular_title: Einfluss von Betaxolol und Timolol auf das Gesichtsfeld bei Glaukompatienten.