Alopecia areata in children: response to treatment with diphencyprone.
Twelve children with extensive alopecia areata or alopecia totalis were treated with the contact allergen diphencyprone. The duration of treatment ranged from 5 months to 1 year. Eight of the 12 (67%) regrew scalp hair and in four (33%) there was a complete regrowth. Six months after treatment was discontinued three of the four children with complete regrowth maintained their hair, one had lost all the regrowth and a further child with patchy regrowth at the end of treatment subsequently regrew hair completely while off therapy.
Hull
S M
SM
Leeds Foundation for Dermatological Research, General Infirmary, Leeds, U.K.
Pepall
L
L
Cunliffe
W J
WJ
D000293:Adolescent; D000485:Allergens; D000506:Alopecia Areata / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D003521:Cyclopropanes / Q000009:adverse effects / Q000276:immunology / Q000627:therapeutic use*; D003877:Dermatitis, Contact / Q000276:immunology; D004485:Eczema / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D012536:Scalp Dermatoses / Q000209:etiology; D013997:Time Factors
D000485:Allergens; D003521:Cyclopropanes; C029402:diphenylcyclopropenone