Malignant angioendotheliomatosis presenting as disseminated intravascular coagulopathy.
Disseminated intravascular coagulopathy (DIC) occurred in a patient with hemolytic anemia and anasarca. Skin and muscle biopsy showed intravascular lymphomatosis (malignant angioendotheliomatosis). Combination chemotherapy resulted in resolution of the DIC and anasarca. After an unmaintained 8-month clinical remission, the patient had central nervous system relapse and died. Malignant angioendotheliomatosis is a rare disorder that should be considered among the occult causes of DIC.
Stahl
R L
RL
Department of Medicine, Emory University School of Medicine, Atlanta, Georgia.
Chan
W
W
Duncan
A
A
Corley
C C
CC
D000368:Aged; D015703:Antigens, CD / Q000032:analysis; D001808:Blood Vessels / Q000276:immunology / Q000473:pathology; D004211:Disseminated Intravascular Coagulation / Q000209:etiology*; D004487:Edema / Q000209:etiology; D005260:Female; D006390:Hemangioendothelioma / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007124:Immunoenzyme Techniques; D016400:Lymphoma, Large-Cell, Immunoblastic / Q000150:complications / Q000175:diagnosis*; D014652:Vascular Diseases / Q000150:complications / Q000175:diagnosis*
D015703:Antigens, CD