Expression of membrane-associated lymphotoxin/tumor necrosis factor-beta on human lymphokine-activated killer cells.
A membrane-associated lymphotoxin (LT)-related molecule was detected on human lymphokine-activated killer (LAK) cells by flow cytometric analysis. Kinetic analysis revealed that the LT antigenicity on LAK cells appeared at 9 h after the beginning of culture and was maintained thereafter. By autoradiography, the molecular weight of membrane LT was estimated to be 31 kD and/or 62 kD.
Abe
Y
Y
Second Department of Surgery, Ehime University School of Medicine.
Miyake
M
M
Horiuchi
A
A
Kimura
S
S
Hitsumoto
Y
Y
D002462:Cell Membrane / Q000737:chemistry; D002478:Cells, Cultured; D006801:Humans; D015979:Killer Cells, Lymphokine-Activated / Q000737:chemistry*; D008233:Lymphotoxin-alpha / Q000032:analysis*; D008970:Molecular Weight
D008233:Lymphotoxin-alpha