[The effect of low doses of x-rays on the biochemical processes in the brain and on urinary metabolites in fasted rats].
The effect of mild doses of X-rays (three fractions, each of 100 R) on energy metabolism of the brain of starved rats has been investigated. It is inferred that X-radiation may cause serious detrimental changes of enzymes involved in glucose metabolism (glucose-6-phosphate dehydrogenase and fructose diphosphate aldolase) and in peroxidation (of catalase and lipid peroxidase), and of the acetylcholine activity which is determined by the cholinesterase level. Dynamics of changes in the protein and nucleic acid content of the brain has been studied. It has been shown that the level of 4-HIAA and 3M4HMA in the brain increases after irradiation of starved and normally fed rats.
Hasan
S S
SS
Kushawa
A K
AK
D000818:Animals; D001921:Brain / Q000201:enzymology / Q000378:metabolism / Q000528:radiation effects*; D004734:Energy Metabolism / Q000528:radiation effects; D005215:Fasting / Q000378:metabolism*; D006016:Glycolates / Q000652:urine*; D011829:Radiation Dosage; D051381:Rats; D014642:Vanilmandelic Acid / Q000652:urine*
D006016:Glycolates; C031149:glycolic acid; D014642:Vanilmandelic Acid
Deĭstvie malykh doz rentgenovskogo izlucheniia na biokhimicheskie protsessy v golovnom mozgu i metabolity mochi u golodaiushchikh krys.