title: Bone anomalies in myotonic dystrophy.
abstract: Sixteen patients with myotonic dystrophy underwent CT examination of the skull, and measurement of bone mineral density at lumbar spine and hip by dual-photon absortiometry. The results were compared with those of 20 normal subjects of similar age and sex distribution. Hyperostosis of the calvarium, and increased bone mineral density at lumbar vertebrae were observed. One case showed basal ganglia calcification associated with hyperparathyroidism secondary to deficiency of vitamin D. In the other 15 patients, studies of calcium metabolism were normal. There results suggest the existence of generalized hyperostotic potential in patients with myotonic dystrophy.
authors.affiliation: Neurology Service, Galicia General Hospital, Santiago de Compostela University, Spain.
authors.forename: J R
authors.initials: JR
authors.lastname: Rodriguez
authors.forename: J
authors.initials: J
authors.lastname: Castillo
authors.forename: R
authors.initials: R
authors.lastname: Leira
authors.forename: J
authors.initials: J
authors.lastname: Pardo
authors.forename: M
authors.initials: M
authors.lastname: Lema
authors.forename: M
authors.initials: M
authors.lastname: Noya
mesh_terms: D000293:Adolescent; D000328:Adult; D001479:Basal Ganglia / Q000000981:diagnostic imaging; D015519:Bone Density / Q000502:physiology*; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D002114:Calcinosis / Q000000981:diagnostic imaging*; D002421:Caudate Nucleus / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D004057:Hyperostosis, Diffuse Idiopathic Skeletal / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D009223:Myotonic Dystrophy / Q000000981:diagnostic imaging*; D012886:Skull / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed