Granulocyte enzymes and complement after an anaphylactoid reaction to coronary angiography.
An anaphylactoid reaction following angiography with ioxaglate in a 59-year-old man implied generalized pruritus, angioedema, bronchospasm and hypotension. Leucocytosis and an increased number of neutrophils were observed from 90 min to 8 h after the reaction. Elevated values of the neutrophil specific enzymes elastase and lactoferrin were demonstrated. The concentrations of C3d and CH50 did not change which indicate that no complement activation took place.
Rasmussen
F
F
Department of Diagnostic Radiology, Odense University Hospital, Denmark.
Antonsen
S
S
Georgsen
J
J
D000707:Anaphylaxis / Q000097:blood / Q000139:chemically induced*; D015933:Complement C3d / Q000032:analysis*; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging; D006461:Hemolysis; D006801:Humans; D007485:Ioxaglic Acid / Q000009:adverse effects*; D007781:Lactoferrin / Q000097:blood*; D007964:Leukocytosis / Q000097:blood; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000201:enzymology*; D010196:Pancreatic Elastase / Q000097:blood*
D015933:Complement C3d; D007781:Lactoferrin; D010196:Pancreatic Elastase; D007485:Ioxaglic Acid