title: [The genomic fingerprinting of the causative agents of sapronoses].
abstract: The genome polymorphism of the causative agents of sapronoses (Vibrio cholerae, Legionella and Leptospira) has been studied. The use of the method of genome fingerprinting [correction of dactyloscopy] has been shown to permit the differentiation of closely related strains of such causative agents. The epidemically significant strains of the causative agents of sapronoses, isolated in different geographical regions, have been found to be genotypically related, i.e., they are probably of clonal origin. Avirulent and nontoxigenic strains are genotypically heterogeneous and differ both from one another and from epidemically significant strains. Using V. cholerae as an example, the hypothesis of the appearance of potentially dangerous variants at the epidemic period in the absence of their release at the period between epidemics is considered.
authors.forename: I A
authors.initials: IA
authors.lastname: Shaginian
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Anan'ina
authors.forename: O N
authors.initials: ON
authors.lastname: Tokarskaia
authors.forename: G M
authors.initials: GM
authors.lastname: Grizhebovskiĭ
authors.forename: A F
authors.initials: AF
authors.lastname: Briukhanov
authors.forename: A P
authors.initials: AP
authors.lastname: Ryskov
authors.forename: I S
authors.initials: IS
authors.lastname: Tartakovskiĭ
authors.forename: A L
authors.initials: AL
authors.lastname: Gintsburg
authors.forename: S V
authors.initials: SV
authors.lastname: Prozorovskiĭ
mesh_terms: D016172:DNA Fingerprinting; D015342:DNA Probes; D004269:DNA, Bacterial / Q000235:genetics*; D004783:Environmental Microbiology; D005798:Genes, Bacterial / Q000235:genetics*; D005838:Genotype; D006801:Humans; D007875:Legionella / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D007919:Leptospira / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D009693:Nucleic Acid Hybridization; D011110:Polymorphism, Genetic / Q000235:genetics; D014734:Vibrio cholerae / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D014774:Virulence / Q000235:genetics
chemical_list: D015342:DNA Probes; D004269:DNA, Bacterial
vernacular_title: Genomnaia daktiloskopiia vozbuditeleĭ sapronozov.