title: Characteristics of platelet concentrates, with particular reference to Autopheresis C Plateletcell: correlation between dMPV and other tests for platelet function.
abstract: The quality of platelet concentrates (PC) collected by the Autopheresis C cell separator was assessed in two Regional Transfusion Centres taking part in a multicentre study. This study also enabled the assessment of a new simple, rapid test of platelet function and comparison with more established tests, such as aggregation to adenosine diphosphate, as a tool for the quality testing of PC. The new test, based upon the measurement of mean platelet volume using automated haematological cell analysers, is rapid and uses the same samples as those used to estimate the platelet and leucocyte content of the concentrates. The high correlation between this test and the other tests of platelet function used in the study suggests that it is an ideal tool in the quality testing of platelet concentrates.
authors.affiliation: North London Blood Transfusion Centre, Colindale, UK.
authors.forename: M V
authors.initials: MV
authors.lastname: Vickers
authors.forename: A H
authors.initials: AH
authors.lastname: Ip
authors.forename: M
authors.initials: M
authors.lastname: Cutts
authors.forename: N P
authors.initials: NP
authors.lastname: Tandy
authors.forename: M J
authors.initials: MJ
authors.lastname: Seghatchian
mesh_terms: D000941:Antigens / Q000378:metabolism; D001786:Blood Glucose / Q000378:metabolism; D001792:Blood Platelets / Q000166:cytology* / Q000502:physiology; D001793:Blood Preservation; D004492:Edetic Acid / Q000494:pharmacology; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D010974:Platelet Aggregation; D010976:Platelet Count; D010979:Platelet Function Tests; D010983:Plateletpheresis / Q000295:instrumentation; D014841:von Willebrand Factor / Q000276:immunology
chemical_list: D000941:Antigens; D001786:Blood Glucose; C029417:Von Willebrand antigen; D014841:von Willebrand Factor; D004492:Edetic Acid; D007770:L-Lactate Dehydrogenase