[The effect of drugs that correct regional blood circulation on the function of the parotid salivary glands in the combined treatment of patients with Sjögren's disease].
A study was made of the effect of some drugs that correct microcirculatory disorders (dimethylsulfoxide (DMSO), heparin, novocaine) on the function of the auricular salivary glands (ASG) in combined treatment of 20 patients suffering from Sjögren's disease (SD). It has been established that the use of the indicated remedies is conducive to a more rapid counteracting of the inflammatory process in the ASG, making it possible to stabilize their function for a long time in persons with the initial and marked stages of chronic parotitis (CP) but not preventing repeated exacerbations of CP. In order to maintain the therapeutic level of the response of the vascular bed of the ASG to DMSO, it is desirable that compresses with DMSO in a "pure" form be applied in 6 hours, using a 1% hydrocortisone ointment "laying" 1 to 2 times a day.
Varshavskiĭ
A I
AI
Guberskaia
T A
TA
D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D003729:Dental Care; D004121:Dimethyl Sulfoxide / Q000627:therapeutic use*; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006493:Heparin / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010306:Parotid Gland / Q000098:blood supply* / Q000187:drug effects; D011343:Procaine / Q000627:therapeutic use*; D012039:Regional Blood Flow / Q000187:drug effects; D012074:Remission Induction; D012859:Sjogren's Syndrome / Q000188:drug therapy* / Q000503:physiopathology
D011343:Procaine; D006493:Heparin; D004121:Dimethyl Sulfoxide
Vliianie lekarstvennykh sredstv, korrigiruiushchikh regionarnoe krovoobrashchenie, na funktsional'noe sostoianie okoloushnykh sliunnykh zhelez pri kompleksnom lechenii bol'nykh bolezn'iu Shegrena.