title: Weaning from ventilation after cardiopulmonary bypass: evaluation of a non-invasive technique.
abstract: Weaning of patients from IPPV after cardiopulmonary bypass (CPB) is usually monitored by frequent arterial blood gas analysis. Non-invasive monitoring has the advantage of providing continuous and instantaneous information and could reduce the frequency of arterial blood gas sampling. Twenty patients were studied to determine the reliability of capnometry and pulse oximetry in this situation. The effects of hypothermia and moderate haemodynamic instability were examined. A further 40 patients were then weaned using non-invasive monitoring. Correlation between PaCO2 and PETCO2 was 0.64-0.79 for the mass spectrometer and 0.67-0.81 for the infra-red analyser. No clinical problems arose. The detection rate for mild hypercarbia was 78.6 per cent and 50 per cent for hypoxia. Possible reasons for this are discussed. Once CO2 and O2 gradients are established, pulse oximetry and capnometry provide sufficiently reliable monitoring to enable weaning from IPPV, with the advantage of continuous display, and allow a reduction in the use of arterial blood gas analyses.
authors.affiliation: Department of Anaesthesia, Royal Victoria Hospital, Montreal, Canada.
authors.forename: D E
authors.initials: DE
authors.lastname: Withington
authors.forename: J G
authors.initials: JG
authors.lastname: Ramsay
authors.forename: A T
authors.initials: AT
authors.lastname: Saoud
authors.forename: J
authors.initials: J
authors.lastname: Bilodeau
mesh_terms: D000328:Adult; D000368:Aged; D002245:Carbon Dioxide / Q000032:analysis* / Q000097:blood; D002315:Cardiopulmonary Bypass; D005260:Female; D006801:Humans; D008297:Male; D013058:Mass Spectrometry; D008875:Middle Aged; D010092:Oximetry; D010100:Oxygen / Q000032:analysis / Q000097:blood; D015657:Respiratory Transport; D013696:Temperature; D015300:Ventilator Weaning
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen