Comparison of proteins of simian herpesvirus aotus type 2 and bovine herpesvirus type 4.
Genomes of herpesvirus aotus type 2 (HVA-2) and bovine herpesvirus type 4 (BHV-4) have previously been shown to be closely similar. Moreover, preliminary serological data indicated that HVA-2 is antigenically related to BHV-4. To extend this study, structural components of four BHV-4 strains and HVA-2 were compared by SDS-PAGE, radioimmunoprecipitation and Western blotting. The overall pattern of structural proteins was the same for HVA-2 and BHV-4 but variations were observed in electrophoretic profiles of glycoproteins, mainly of the two major ones (gp6/gp10/gp17 and gp11/VP24). Variations between HVA-2 and BHV-4 glycoproteins were greater than those observed among BHV-4 strains.
Dubuisson
J
J
Department of Virology-Immunology, Faculty of Veterinary Medicine, University of Liège, Belgium.
Danyi
S
S
Bublot
M
M
Pastoret
P P
PP
Thiry
E
E
D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology; D001345:Autoradiography; D015153:Blotting, Western; D002417:Cattle; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D000882:Haplorhini; D006564:Herpesviridae / Q000032:analysis* / Q000276:immunology; D011233:Precipitin Tests; D013045:Species Specificity; D014764:Viral Proteins / Q000276:immunology*
D000914:Antibodies, Viral; D014764:Viral Proteins