title: Crystalluria in marathon runners. III. Stone-forming subjects.
abstract: In order to investigate further the possible relationship between urinary stone formation and marathon running, the crystalluria in seven male, stone forming runners was characterized. Particle size distribution curves (Coulter counter) and crystal number, size and morphology (scanning electron microscopy) were measured. These studies suggest that urinary stone formation may be accelerated in those subjects with previous histories of renal stone formation but that the nature of the crystalluria is favourably affected by an increase in fluid intake. The presence of large quantities of mucoid material in the urine of "natural" stone formers and its absence in the urine of stone-forming runners is cited as evidence for the existence of different aetiological mechanisms in these groups. It is concluded that while natural stone formers may be at chronic risk of stone formation due to pathological factors, marathon runners may be at acute risk due to factors associated with long distance running itself.
authors.affiliation: Department of Chemistry, University of Cape Town, Republic of South Africa.
authors.forename: A L
authors.initials: AL
authors.lastname: Rodgers
authors.forename: K G
authors.initials: KG
authors.lastname: Greyling
authors.forename: T D
authors.initials: TD
authors.lastname: Noakes
mesh_terms: D000328:Adult; D002129:Calcium Oxalate / Q000652:urine; D003460:Crystallization; D004327:Drinking Behavior; D004577:Electron Probe Microanalysis; D006801:Humans; D007669:Kidney Calculi / Q000453:epidemiology / Q000209:etiology / Q000652:urine*; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D010316:Particle Size; D012307:Risk Factors; D012420:Running
chemical_list: D002129:Calcium Oxalate