Studying DNA modifications and DNA-protein interactions in vivo. A window onto the native genome.
The study of native genomes has been greatly facilitated by the use of direct genomic sequencing and footprinting strategies. This review provides an overview of the techniques involved and presents some highlights of the biological results obtained with these methods.
Saluz
H P
HP
IRBM, Pomezia, Roma, Italy.
Wiebauer
K
K
Wallace
A
A
D000818:Animals; D001483:Base Sequence; D004247:DNA / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000378:metabolism*; D005821:Genetic Techniques; D015698:Genomic Library; D006801:Humans; D016133:Polymerase Chain Reaction
D004268:DNA-Binding Proteins; D004247:DNA