title: Lumbar intervertebral disc prosthesis. An experimental study.
abstract: To provide a more effective treatment and improve the outcome of surgical treatment of lumbar intervertebral disc protrusion, the values of lumbar intervertebral disc prosthesis (LIDP) were investigated. LIDP was specially designed and made of silicone rubber. The properties of material mechanics were investigated by compressive test and damage test of LIDP specimens. The biocompatibilities of LIDP were observed experimentally in monkeys. The surgical applicabilities were studied by in vitro experiments of fresh human lumbar spine. The results showed that LIDP has the advantages of good biomechanical applicability, biocompatibility and surgical applicability. LIDP is able to maintain the intervertebral space, stress balance and stability of the lumbar spine. after lumbar intervertebral disc excision, the replacement of LIDP could restore the functions of the lumbar spine and improve the curative results of disc excision.
authors.affiliation: Department of Orthopedics, Changzheng Hospital, Shanghai.
authors.forename: T S
authors.initials: TS
authors.lastname: Hou
authors.forename: K Y
authors.initials: KY
authors.lastname: Tu
authors.forename: Y K
authors.initials: YK
authors.lastname: Xu
authors.forename: Z B
authors.initials: ZB
authors.lastname: Li
authors.forename: A H
authors.initials: AH
authors.lastname: Cai
authors.forename: H C
authors.initials: HC
authors.lastname: Wang
mesh_terms: D000328:Adult; D000818:Animals; D005260:Female; D000882:Haplorhini; D006801:Humans; D007403:Intervertebral Disc; D007405:Intervertebral Disc Displacement / Q000601:surgery*; D008159:Lumbar Vertebrae; D008297:Male; D019736:Prostheses and Implants; D012826:Silicone Elastomers
chemical_list: D012826:Silicone Elastomers