[Carbohydrate metabolism in the brain in comatose states. Mechanisms of gluconeogenesis].
Glucose release and lactate uptake by the brain during coma is discussed. A hypothesis of autonomous gluconeogenesis in the brain is suggested. To substantiate the hypothesis use is made of the literature data on the presence in the brain of stimuli, and its provision with substrates and gluconeogenetic enzyme apparatus. Special attention is paid to the problem of gluconeogenesis energy supply during hypoxia, using proton or sodium potentials.
Gruzman
A B
AB
Khapiĭ
Kh Kh
KhKh
D001786:Blood Glucose / Q000378:metabolism*; D001921:Brain / Q000378:metabolism*; D003128:Coma / Q000378:metabolism*; D005943:Gluconeogenesis / Q000502:physiology*; D006801:Humans; D007773:Lactates / Q000097:blood*
D001786:Blood Glucose; D007773:Lactates
Uglevodnyĭ obmen v golovnom mozge pri komatoznykh sostoianiiakh. Mekhanizmy gliukoneogeneza.