title: Clinical significance of hypouricemia in hospitalized patients.
abstract: Serum uric acid was measured in 586 normal subjects and 1,220 hospitalized patients. Hypouricemia was noted in 0.34% of the normal subjects and 2.54% of the hospitalized patients. Among hospitalized patients with hypouricemia, 22 were on medication, including allopurinol, anticancer drugs, antibiotics and glucocorticoids. Twenty-one patients had liver disorders and 11 of them had received transfusions. Neoplastic diseases were noted in 14 patients. Thus, hypouricemia was found to be relatively common in hospitalized patients, and seems to be caused mainly by medication, neoplastic diseases, liver disorders and transfusions.
authors.affiliation: First Department of Internal Medicine, Tottori University School of Medicine, Yonago, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ogino
authors.forename: I
authors.initials: I
authors.lastname: Hisatome
authors.forename: M
authors.initials: M
authors.lastname: Saitoh
authors.forename: J
authors.initials: J
authors.lastname: Miyamoto
authors.forename: R
authors.initials: R
authors.lastname: Ishiko
authors.forename: J
authors.initials: J
authors.lastname: Hasegawa
authors.forename: H
authors.initials: H
authors.lastname: Kotake
authors.forename: H
authors.initials: H
authors.lastname: Mashiba
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000493:Allopurinol / Q000009:adverse effects; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D000970:Antineoplastic Agents / Q000009:adverse effects; D002648:Child; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008107:Liver Diseases / Q000097:blood; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000097:blood; D012189:Retrospective Studies; D065227:Transfusion Reaction; D014527:Uric Acid / Q000097:blood* / Q000652:urine
chemical_list: D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D005938:Glucocorticoids; D014527:Uric Acid; D000493:Allopurinol