Nematocidal principles in "oakmoss absolute" and nematocidal activity of 2,4-dihydroxybenzoates.
Nematocidal principles obtained from oakmoss absolute were identified as methyl 2,4-dihydroxy-3,6-di-methylbenzoate (2), ethyl 3-formyl-2,4-dihydroxy-6-methylbenzoate (4), and ethyl 5-chloro-3-formyl-2,4-dihydroxy-6-methylbenzoate (7). In relation to their structures, the nematocidal activity of 2,4-dihydroxybenzoates of methyl to tetradecyl was tested and the strongest activity was found in the octyl ester (minimal lethal concentration = 13 microM).
Ahad
A M
AM
Faculty of Pharmaceutical Sciences, Kanazawa University, Japan.
Goto
Y
Y
Kiuchi
F
F
Tsuda
Y
Y
Kondo
K
K
Sato
T
T
D000818:Animals; D000969:Antinematodal Agents / Q000302:isolation & purification* / Q000494:pharmacology; D062385:Hydroxybenzoates / Q000302:isolation & purification / Q000494:pharmacology; D008011:Lichens / Q000032:analysis*; D013329:Structure-Activity Relationship
D000969:Antinematodal Agents; D062385:Hydroxybenzoates