title: Two receptor binding regions of human FSH show sense-antisense similarity to the human FSH receptor.
abstract: The sequences of two receptor binding regions of the beta-subunit of the human follicle-stimulating hormone (hFSH-beta) were compared with the DNA-derived antisense peptide sequence of the hFSH receptor. A striking sense-antisense similarity was established between these receptor binding regions and the hFSH receptor. Based on this sense-antisense similarity four putative hormone binding regions on the N-terminal extracellular region of the hFSH receptor are identified.
authors.affiliation: Department of Histology, Vrije Universiteit, Amsterdam, The Netherlands.
authors.forename: J W
authors.initials: JW
authors.lastname: Slootstra
authors.forename: E W
authors.initials: EW
authors.lastname: Roubos
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D001665:Binding Sites; D016373:DNA, Antisense / Q000235:genetics*; D005640:Follicle Stimulating Hormone / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D008961:Models, Structural; D008969:Molecular Sequence Data; D014176:Protein Biosynthesis; D011487:Protein Conformation; D011962:Receptors, FSH / Q000235:genetics* / Q000378:metabolism; D012689:Sequence Homology, Nucleic Acid
chemical_list: D016373:DNA, Antisense; D011962:Receptors, FSH; D005640:Follicle Stimulating Hormone