Survey on use of antimicrobial agents and bacterial resistance in Huashan Hospital.
A cross-section study was carried out to assess the general patterns in use of antimicrobial agents and the trends of bacterial resistance in Huashan Hospital. Of 2,400 patients whose charts were reviewed, 61% were given such drugs. 3,596 antibiotic courses were prescribed. Gentamicin was most frequently used. Results of the susceptibility test of 320 bacterial strains showed a high percentage of resistance against gentamicin, ampicillin, and chloramphenicol. Our findings suggest that antibiotic policies in the hospital need reappraising.
Tung
H H
HH
Huashan Hospital, Shanghai Medical University.
Pan
G Z
GZ
Chen
M K
MK
Yan
B J
BJ
Wong
X H
XH
Xu
Z Y
ZY
Kunin
C M
CM
D000293:Adolescent; D000328:Adult; D000368:Aged; D000668:Ampicillin Resistance; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002648:Child; D002702:Chloramphenicol Resistance; D003430:Cross-Sectional Studies; D004352:Drug Resistance, Microbial; D004363:Drug Utilization; D005260:Female; D005839:Gentamicins / Q000494:pharmacology; D006801:Humans; D007239:Infections / Q000188:drug therapy*; D007711:Klebsiella pneumoniae / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control; D011550:Pseudomonas aeruginosa / Q000187:drug effects
D000900:Anti-Bacterial Agents; D005839:Gentamicins