[Biological activity of gamma-irradiated serum albumin].
Gamma-irradiated serum albumin activated L-tyrosine oxidation to 3,4-dioxyphenyl alanine (DOPA) and forms adducts with DOPA oxidation products. These adducts are more resistant to proteolysis and have bactericidal and mutagenic capacity. A possible role of such adducts in a radiation damage to the organism is discussed.
Kopylov
V A
VA
Revin
A F
AF
Iurov
S S
SS
Shchelkaeva
N V
NV
Kuzin
A M
AM
D004295:Dihydroxyphenylalanine / Q000378:metabolism; D004347:Drug Interactions; D005720:Gamma Rays; D066298:In Vitro Techniques; D010084:Oxidation-Reduction / Q000528:radiation effects; D011485:Protein Binding / Q000528:radiation effects; D012710:Serum Albumin, Bovine / Q000378:metabolism / Q000528:radiation effects*; D012996:Solutions; D014443:Tyrosine / Q000378:metabolism
D012996:Solutions; D012710:Serum Albumin, Bovine; D014443:Tyrosine; D004295:Dihydroxyphenylalanine
Biologicheskaia aktivnost' gamma-obluchennogo syvorotochnogo al'bumina.