title: Research note: ability of fenthion to increase gizzard erosion in broiler chicks.
abstract: Fenthion, an irreversible cholinesterase inhibitor, was used to study the role of the cholinergic system on the development of gizzard erosion. Fenthion increases the gizzard erosion score in a dose-dependent manner and this effect became significant at levels higher than .1 ppm (p less than .05). An inverse relationship between plasma cholinesterase activity and pesticide concentration was also observed at doses higher than 1 ppm (P less than .05). These results show the necessity to evaluate organophosphate pesticide levels during the selection of fish meals in poultry.
authors.affiliation: Laboratory of Biochemistry and Biology, Nutrition and Food Engineering, Santiago, Chile.
authors.forename: S
authors.initials: S
authors.lastname: Lavandero
authors.forename: M
authors.initials: M
authors.lastname: Neira
authors.forename: C
authors.initials: C
authors.lastname: López
authors.forename: R
authors.initials: R
authors.lastname: Gallardo
authors.forename: E
authors.initials: E
authors.lastname: Guerrero
authors.forename: M
authors.initials: M
authors.lastname: Rutman
mesh_terms: D000818:Animals; D002645:Chickens; D004305:Dose-Response Relationship, Drug; D005284:Fenthion / Q000009:adverse effects*; D005895:Gizzard, Avian / Q000187:drug effects*; D011201:Poultry Diseases / Q000139:chemically induced*; D011897:Random Allocation; D012044:Regression Analysis; D013272:Stomach Diseases / Q000139:chemically induced / Q000662:veterinary*
chemical_list: D005284:Fenthion