title: Synthesis and biological activity of some 4-substituted pyrimidines and fused pyrimidines.
abstract: The synthesis of 4-beta-cyanoethylthiopyrimidine 2 and 4-chloropyrimidine 8a was chieved from 4-mercapto-5-acetylpyrimidine (1a). Also the synthesis of thienopyrimidine-7,7-dioxide 6, 4-arylaminopyrimidines 9a-e, 4-alkoxypyrimidines 11a, b, pyrimidoquinazoline 10, thienopyrimidines 19a, b and tetrazolopyrimidine 18 was described.
authors.affiliation: Chemistry Department, Faculty of Science, Zagazig University, Egypt.
authors.forename: S
authors.initials: S
authors.lastname: el-Bahaie
authors.forename: A
authors.initials: A
authors.lastname: el-Deeb
authors.forename: M C
authors.initials: MC
authors.lastname: Assy
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D001419:Bacteria / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D011743:Pyrimidines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D012475:Salmonella / Q000187:drug effects; D013056:Spectrophotometry, Ultraviolet; D013210:Staphylococcus / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D011743:Pyrimidines