Postthaw stability of fibrinogen in cryoprecipitate stored between 1 and 6 degrees C.
The fibrinogen activity in thawed cryoprecipitate stored between 1 and 6 degrees C is maintained essentially unchanged in most bags for a month. Occasionally, a bag will have a reduction in fibrinogen. If pooling has not occurred, thawed cryoprecipitate should be useful as a source of fibrinogen for a period of time considerably in excess of the 6 hours allowed for its use as a source of factor VIII or von Willebrand factor.
Howard
P L
PL
Department of Pathology, College of Medicine, University of Vermont, Burlington.
Bovill
E G
EG
Golden
E
E
D011232:Chemical Precipitation; D004355:Drug Stability; D005169:Factor VIII; D005340:Fibrinogen; D006801:Humans; D013696:Temperature; D013997:Time Factors
C026912:cryoprecipitate coagulum; D005169:Factor VIII; D005340:Fibrinogen