Fluoxetine and norfluoxetine are potent inhibitors of P450IID6--the source of the sparteine/debrisoquine oxidation polymorphism.
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D005473:Fluoxetine / Q000031:analogs & derivatives* / Q000494:pharmacology*; D006801:Humans; D007099:Imipramine / Q000378:metabolism; D008862:Microsomes, Liver / Q000187:drug effects*; D011110:Polymorphism, Genetic
D005473:Fluoxetine; C036139:norfluoxetine; D007099:Imipramine