Tissue-plasminogen activator for pulmonary embolism resulting in shock: two case reports and discussion of the literature.
Two patients with significant relative contraindications to fibrinolysis, and with refractory shock caused by acute pulmonary embolism, who were successfully treated with recombinant tissue-type plasminogen activator (rt-PA) are reported. The role of rt-PA in the management of pulmonary embolism is discussed, and pertinent literature is reviewed.
Mitchell
J P
JP
Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110.
Trulock
E P
EP
D000328:Adult; D000368:Aged; D006801:Humans; D008297:Male; D011655:Pulmonary Embolism / Q000150:complications* / Q000628:therapy*; D011994:Recombinant Proteins / Q000627:therapeutic use; D012769:Shock / Q000209:etiology*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator