title: Origin of so-called mesothelioma of the atrioventricular node. An immunohistochemical study.
abstract: To determine the origin of a mesothelioma of the atrioventricular node, immunohistochemical studies that used various antibodies, including the antibody against mesothelial cells, were performed on a mesothelioma of the atrioventricular node in a case. The lining cells of the tubules that composed the tumor were negative when tested with anti-mesothelial cell antibodies. Carcinoembryonic antigen was negative, but the secretory component was positive. Serotonin and calcitonin were positive in a few cells. We concluded that a mesothelial origin was unlikely, and it was suggested that the tumor was of an entodermal origin.
authors.affiliation: Department of Pathology, Iwate Medical University School of Medicine, Morioka, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Monma
authors.forename: R
authors.initials: R
authors.lastname: Satodate
authors.forename: A
authors.initials: A
authors.lastname: Tashiro
authors.forename: I
authors.initials: I
authors.lastname: Segawa
mesh_terms: D001283:Atrioventricular Node / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D006338:Heart Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008654:Mesothelioma / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D008875:Middle Aged