title: Use of TAO without methylprednisolone in the treatment of severe asthma.
abstract: The antimicrobial agent troleandomycin (TAO) has been shown to be effective in reducing corticosteroid requirements in patients with corticosteroid-dependent asthma. To our knowledge, the efficacy of TAO without concomitant use of corticosteroids has never been documented. We report the case of a 12-year-old patient with corticosteroid-dependent asthma who has remained asymptomatic and without any evidence of pulmonary deterioration during treatment with TAO without concomitant use of corticosteroids.
authors.affiliation: Division of Pulmonary Medicine, Children's Hospital of Philadelphia.
authors.forename: S M
authors.initials: SM
authors.lastname: Rosenberg
authors.forename: H
authors.initials: H
authors.lastname: Gerhard
authors.forename: M M
authors.initials: MM
authors.lastname: Grunstein
authors.forename: C M
authors.initials: CM
authors.lastname: Schramm
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000188:drug therapy* / Q000503:physiopathology; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008775:Methylprednisolone / Q000008:administration & dosage* / Q000627:therapeutic use; D015656:Respiratory Mechanics / Q000187:drug effects; D014217:Troleandomycin / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D014217:Troleandomycin; D008775:Methylprednisolone