[Effects of opioid neuropeptides on the prostaglandin system and lipid peroxidation processes in the myocardium during stress-induced damage].
The stress was subsequenced by lowering of Thromboxane A2 level and activation of peroxidation of lipids without any changes of prostacyclin content in myocardium. It was found that the pre-increase of the opioid peptides in blood plasma led to the absence of prostacyclin and thromboxane dynamic and myocardial lipids peroxidation inhibition during the subsequent stress.
Lishmanov
Iu B
IuB
Travkov
Iu A
IuA
Fedotova
T V
TV
Rebrova
T Iu
TIu
D000818:Animals; D000897:Anti-Ulcer Agents / Q000494:pharmacology*; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives* / Q000494:pharmacology; D011464:Epoprostenol / Q000378:metabolism; D015227:Lipid Peroxidation; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D011453:Prostaglandins / Q000378:metabolism*; D051381:Rats; D013315:Stress, Psychological / Q000378:metabolism*; D013565:Sympatholytics / Q000494:pharmacology*; D013928:Thromboxane A2 / Q000378:metabolism
D000897:Anti-Ulcer Agents; D011453:Prostaglandins; D013565:Sympatholytics; D013928:Thromboxane A2; D016308:Enkephalin, Leucine-2-Alanine; D011464:Epoprostenol; C040996:enkephalin-Leu, Ala(2)-Arg(6)-
Vliianie opioidnykh neĭropeptidov na sistemu prostaglandinov i protsessy perekisnogo okisleniia lipidov v miokarde pri ego stressornom povrezhdenii.