Individual differences in aging: behavioral and neural analyses.
Aged populations have remarkable variability in recent memory and cognitive mapping. Although some individuals may have substantial age-related impairments, others perform almost as well as young individuals. This paper reviews the relevant data on aged rats and indicates two challenges for biomarkers of aging. The first is to provide an appropriate quantitative description of these individual differences. The second is to use them effectively as markers for age-related changes in psychological functions and their neural substrates.
Olton
D S
DS
Department of Psychology, Johns Hopkins University, Baltimore, Maryland 21218.
Markowska
A
A
Breckler
S J
SJ
Wenk
G L
GL
Pang
K C
KC
Koliatsos
V
V
D000375:Aging / Q000378:metabolism / Q000502:physiology*; D000818:Animals; D015415:Biomarkers; D003071:Cognition; D008568:Memory; D011597:Psychomotor Performance
D015415:Biomarkers