A case of primary systemic amyloidosis with AA protein.
We present here a case of young adult-onset primary systemic amyloidosis with AA protein. A 29-year-old male presenting with macrohematuria was transferred to our hospital because of aggravation of renal function. Amyloid protein was detected in the bladder, stomach and thyroid. The amyloid protein proved to be AA type by potassium permanganate histochemical analysis. Since secondary amyloidosis was excluded by the laboratory data and there was no family history of amyloidosis, a diagnosis of primary systemic amyloidosis with AA protein was reached. Although the patient was prescribed dimethyl sulphoxide, his renal function worsened with gastrocolic symptoms and a bleeding tendency. Hemodialysis (HD) was then initiated. After starting the HD, the patient's general condition recovered and subsequently the patient on treatment with maintenance HD was discharged.
Okada
K
K
2nd Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan.
Takahashi
S
S
Horiuchi
K
K
Nagura
Y
Y
Hatano
M
M
D000328:Adult; D000686:Amyloidosis / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy; D005753:Gastric Mucosa / Q000378:metabolism; D006801:Humans; D008297:Male; D006435:Renal Dialysis; D000685:Serum Amyloid A Protein / Q000378:metabolism*; D013961:Thyroid Gland / Q000378:metabolism; D001743:Urinary Bladder / Q000378:metabolism
D000685:Serum Amyloid A Protein