An association of primary hyperparathyroidism and non medullary thyroid carcinoma.
A 40-year-old woman was admitted because of long-lasting asymptomatic hypercalcaemia. About 2 years earlier she underwent thyroidectomy and further 131 I therapy because of well-differentiated non medullary thyroid carcinoma. On admission biochemical data and hormonal values (serum calcium, serum phosphorus, i-PTH) were consistent with primary hyperparathyroidism; ultrasonography, computed tomography, thallium-technetium scintiscanning disclosed right paratracheal mass; on surgical procedure a right parathyroid adenoma was removed. The coexistence of non medullary thyroid carcinoma and primary hyperparathyroidism is rare: the prior 131 I therapy might be linked to subsequent development of parathyroid adenoma.
Bisbocci
D
D
Dipartimento di Medicina ed Oncologia sperimentale, Sezione di Medicina interna, Ospedale San Vito, Torino.
Gambino
M
M
Modina
P
P
Livorno
P
P
Ossola
M
M
Marinone
C
C
Pellerito
R
R
Cottino
F
F
D000236:Adenoma / Q000150:complications / Q000175:diagnosis; D000328:Adult; D002277:Carcinoma / Q000150:complications* / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000175:diagnosis / Q000209:etiology; D006961:Hyperparathyroidism / Q000175:diagnosis / Q000209:etiology*; D010282:Parathyroid Neoplasms / Q000150:complications / Q000175:diagnosis; D013964:Thyroid Neoplasms / Q000150:complications* / Q000628:therapy; D013997:Time Factors