Three-dimensional collagen architecture in bovine articular cartilage.
The three-dimensional architecture of bovine articular cartilage collagen and its relationship to split lines has been studied with scanning electron microscopy. In the middle and superficial zones, collagen was organised in a layered or leaf-like manner. The orientation was vertical in the intermediate zone, curving to become horizontal and parallel to the articular surface in the superficial zone. Each leaf consisted of a fine network of collagen fibrils. Adjacent leaves merged or were closely linked by bridging fibrils and were arranged according to the split-line pattern. The surface layer (lamina splendens) was morphologically distinct. Although ordered, the overall collagen structure was different in each plane (anisotropic) a property described in previous morphological and biophysical studies. As all components of the articular cartilage matrix interact closely, the three-dimensional organisation of collagen is important when considering cartilage function and the processes of cartilage growth, injury and repair.
Jeffery
A K
AK
University of Otago, Dunedin, New Zealand.
Blunn
G W
GW
Archer
C W
CW
Bentley
G
G
D000818:Animals; D002358:Cartilage, Articular / Q000648:ultrastructure*; D002417:Cattle; D003094:Collagen / Q000648:ultrastructure*; D005614:Freeze Fracturing; D008855:Microscopy, Electron, Scanning
D003094:Collagen