title: [A case report of a thrombosed mitral prosthesis diagnosed by 111In-oxine platelets scintigraphy].
abstract: The purpose of this report was to evaluate the efficacy of 111In-oxine labeled platelets scintigraphy for detection of thrombus in the prosthetic valve. A 50-year-old man underwent re-mitral valve replacement with a Björk-Shiley prosthesis because of malfunction of the xenograft in a previous operation. Almost one year later, this patient suffered from peripheral embolism and sight disturbance. There was no evidence of a thrombosed valve although it was suspected. Cineradiography showed the valve almost fully open, and there were no abnormal sounds when the valve closed. 111In-oxine labeled platelets scintigraphy was performed for the detection of thrombus in the mitral position. Hot areas of high quality in the scintigram were demonstrated in the mitral position. As a result, Björk-Shiley prosthesis was replaced with a Duromedics prosthesis. A small thrombus (10mm) surrounded by fresh tiny thrombi was found in a minor orifice of the Björk-Shiley prosthesis.
authors.affiliation: Department of Cardiovascular Surgery, National Ohsaka Hospital.
authors.forename: M
authors.initials: M
authors.lastname: Otaki
authors.forename: M
authors.initials: M
authors.lastname: Kawashima
authors.forename: A
authors.initials: A
authors.lastname: Yamaguchi
authors.forename: N
authors.initials: N
authors.lastname: Kitamura
mesh_terms: D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve; D009942:Organometallic Compounds; D015125:Oxyquinoline / Q000031:analogs & derivatives; D011183:Postoperative Complications / Q000175:diagnosis; D013927:Thrombosis / Q000175:diagnosis*
chemical_list: D009942:Organometallic Compounds; C032950:indium oxine; D015125:Oxyquinoline