Testicular plasmacytoma. A case report with immunohistochemical studies and literature review.
Plasmacytomas of the testes are extremely rare tumors, especially when occurring in the absence of a previous or concurrent diagnosis of multiple myeloma. We present a case of solitary testicular plasmacytoma in a 71-year-old man who had no clinical evidence of myeloma. Immunohistochemical stains showed monoclonal cytoplasmic production of IgA-kappa within tumor cells. A summary of the other reported cases of testicular plasmacytoma is presented. Plasmacytoma of the testes, while occasionally manifesting as a solitary, primary lesion, most likely is a precocious, highly unusual manifestation of systemic multiple myeloma.
Oppenheim
P I
PI
Department of Pathology, Kaiser Permanente Medical Center, Woodland Hills, Calif 91365.
Cohen
S
S
Anders
K H
KH
D000368:Aged; D006801:Humans; D007124:Immunoenzyme Techniques; D007070:Immunoglobulin A / Q000032:analysis; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D008297:Male; D010954:Plasmacytoma / Q000276:immunology / Q000473:pathology*; D013736:Testicular Neoplasms / Q000276:immunology / Q000473:pathology*
D007070:Immunoglobulin A; D007145:Immunoglobulin kappa-Chains