Human aortic proteoglycans of subjects from districts of high and low prevalence of atherosclerosis in China.
The contents of three species of proteoglycans (PGs), heparan sulfate PG(HSPG), chondroitin sulfate PG(CSPG) and dermatan sulfate chondroitin sulfate PG(DSCSPG), in human thoracic aortas of subjects from districts of high (Beijin, in North China) and low (Nanning, in South China) prevalence of atherosclerosis in China were quantitated. Higher aortic HSPG and DSCSPG (but lower DS) in samples from Nanning than those from Beijing might be implicated in the lower prevalence of atherosclerosis in the former.
Chang
Y S
YS
Division of Biochemistry, Chinese Academy of Medical Sciences, Beijing.
Zhang
C L
CL
Zhao
P Z
PZ
Deng
Z L
ZL
D000293:Adolescent; D000328:Adult; D001013:Aorta, Thoracic / Q000378:metabolism*; D001161:Arteriosclerosis / Q000453:epidemiology / Q000378:metabolism*; D002681:China / Q000453:epidemiology; D011508:Chondroitin Sulfate Proteoglycans / Q000378:metabolism; D002809:Chondroitin Sulfates / Q000378:metabolism; D002850:Chromatography, Gel; D002852:Chromatography, Ion Exchange; D003871:Dermatan Sulfate / Q000031:analogs & derivatives / Q000378:metabolism; D004588:Electrophoresis, Cellulose Acetate; D005260:Female; D019812:Heparan Sulfate Proteoglycans; D006497:Heparan Sulfate / Q000378:metabolism; D006801:Humans; D008297:Male; D015995:Prevalence; D011509:Proteoglycans / Q000378:metabolism*
D011508:Chondroitin Sulfate Proteoglycans; D002809:Chondroitin Sulfates; D003871:Dermatan Sulfate; D019812:Heparan Sulfate Proteoglycans; D006497:Heparan Sulfate; D011509:Proteoglycans; C069524:dermatan sulfate chondroitin sulfate