title: Differences in mortality from thermal injury between pediatric and adult patients.
abstract: Children differ from adults in their responses to thermal injury, as reflected by higher reported mortality rates for equivalent major injuries. The age at which children's survival rates equal those of young adults has not been well defined, and some investigators have recently claimed that pediatric and adult burn mortality do not differ. We evaluated age-related mortality among 1,443 consecutive patients without inhalation injury treated from 1978 to 1988, inclusively. The sample consisted of 595 children aged 12 years or less, 243 children aged 13 to 20 years, and 605 young adults aged 21 to 40 years who served as a comparison group of patients with the best predicted survival. We separately examined mortality in patients with burns exceeding 30% total body surface area. There were no significant differences in mortality between age groups for the study sample as a whole, but among patients with large burns, children aged 0 to 48 months had higher mortality than comparably injured adults (31% v 12%, P less than .05 by analysis of covariance). Improvements in survival were also demonstrated between the first and second halves of the study period for children aged 25 months to 8 years. These data indicate that children 48 months of age and younger do not tolerate large thermal injuries as well as adults. Improvements in pediatric burn survival are being achieved in most age groups.
authors.affiliation: Department of Surgery, University of Utah Medical Center, Salt Lake City.
authors.forename: E J
authors.initials: EJ
authors.lastname: Erickson
authors.forename: S W
authors.initials: SW
authors.lastname: Merrell
authors.forename: J R
authors.initials: JR
authors.lastname: Saffle
authors.forename: J J
authors.initials: JJ
authors.lastname: Sullivan
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002056:Burns / Q000453:epidemiology / Q000401:mortality*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012042:Registries / Q000706:statistics & numerical data; D014194:Traumatology / Q000706:statistics & numerical data*; D014589:Utah / Q000453:epidemiology