Magnetic-resonance imaging used for determining fat distribution in obesity and diabetes.
Computed-tomography scanning and magnetic-resonance imaging (MRI) have been used to quantify intraabdominal and subcutaneous fat depots. In this study MRI was used to define fat-distribution patterns in 24 obese females with non-insulin-dependent diabetes (NIDDM) and 12 females with simple obesity. Subjects had anthropometric measurements and single-slice abdominal scans performed at the umbilicus. In addition, in 10 of the nondiabetic females, measurements were repeated after 10 wk of a very-low-calorie diet. Nondiabetic females had significantly less intraabdominal fat (P less than 0.01) than did the diabetics but had equivalent subcutaneous fat. There was no significant relationship between waist-to-hip ratio and intraabdominal fat, subcutaneous fat, or their ratio. After a weight loss of 10.6 +/- 3.8 kg there were significant decreases in both intraabdominal and subcutaneous fat (P less than 0.01). Weight loss is associated with decreases in fat in both depots.
Gray
D S
DS
Department of Family Medicine, University of Southern California, Los Angeles County/University of Southern California Medical Center.
Fujioka
K
K
Colletti
P M
PM
Kim
H
H
Devine
W
W
Cuyegkeng
T
T
Pappas
T
T
D000273:Adipose Tissue / Q000473:pathology*; D000328:Adult; D000367:Age Factors; D000886:Anthropometry; D015992:Body Mass Index; D001835:Body Weight; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000473:pathology*; D004038:Diet, Reducing; D002149:Energy Intake; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009765:Obesity / Q000150:complications / Q000473:pathology*; D012044:Regression Analysis; D012984:Software