HIV-1: seven facets of functional molecular mimicry.
Molecular mimicry, where structural properties borne by a pathogen "imitate" or "simulate" molecules of the host, is shown to take make different forms in the molecular biology of the human immunodeficiency virus type 1 (HIV-1). There is considerable evidence that a number of important immunopathologic processes are incited by HIV-1 infection, due to molecular mimicry. Accordingly, a systematic review of this evidence is intended to define the fundamental immunopathogenic properties of this virus in terms relevant to the science of acquired immunodeficiency syndrome (AIDS) susceptibility, prevention, and treatment.
Bjork
R L
RL
BioTelesis Corporation, Solana Beach, CA.
D000220:Adaptation, Biological; D000595:Amino Acid Sequence; D016384:Consensus Sequence; D005956:Glucose-6-Phosphate Isomerase / Q000276:immunology; D015658:HIV Infections / Q000276:immunology*; D015497:HIV-1 / Q000235:genetics / Q000276:immunology*; D006680:HLA Antigens / Q000276:immunology; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D008969:Molecular Sequence Data; D012191:Retroviridae Proteins / Q000235:genetics / Q000276:immunology
D006680:HLA Antigens; D007136:Immunoglobulins; D012191:Retroviridae Proteins; D005956:Glucose-6-Phosphate Isomerase