[Structure of tryptic fragments of a neurotoxin from black widow spider venom].
The N-terminal amino acid sequence of a neurotoxin from the venom of Latrodectus mactans tredecimguttatus (alpha-latrotoxin) was determined. Latrotoxin was subjected to the tryptic cleavage and total or partial amino acid sequences of 25 peptides were established. In total the tryptic fragments contained 252 amino acid residues. Essential structural information on cloning of the latrotoxin structural gene was obtained.
Volkova
T M
TM
Galkina
T G
TG
Kudelin
A B
AB
Grishin
E V
EV
D000595:Amino Acid Sequence; D000818:Animals; D001740:Black Widow Spider; D002851:Chromatography, High Pressure Liquid; D004591:Electrophoresis, Polyacrylamide Gel; D005796:Genes; D008969:Molecular Sequence Data; D010449:Peptide Mapping; D013111:Spider Venoms / Q000235:genetics*; D014357:Trypsin
D013111:Spider Venoms; C020763:alpha-latrotoxin; D014357:Trypsin
Struktura tripticheskikh fragmentov neĭrotoksina iz iada pauka karakurta.