Failure of elastin development in hypoplastic lungs associated with oligohydramnios: an electronmicroscopic study.
Pulmonary hypoplasia associated with oligohydramnios results in delayed maturation of fetal lung as assessed at light microscope level. Using an elastin-specific electron-microscopic staining technique, we report absent elastic tissue development in the septal crests of these lungs even at term.
Haidar
A
A
Department of Histopathology, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK.
Ryder
T A
TA
Wigglesworth
J S
JS
D004547:Elastic Tissue / Q000196:embryology*; D004549:Elastin / Q000032:analysis*; D005315:Fetal Diseases / Q000378:metabolism / Q000473:pathology; D005865:Gestational Age; D006801:Humans; D008168:Lung / Q000002:abnormalities* / Q000737:chemistry / Q000196:embryology / Q000648:ultrastructure; D008854:Microscopy, Electron; D016104:Oligohydramnios / Q000150:complications*
D004549:Elastin