Effect of thiamine on glucose utilization in hepatic cirrhosis.
Thiamine, an essential co-enzyme, improves glucose utilization. Thiamine hydrochloride (50 mg per capita per day for 30 days), given to 25 patients with liver cirrhosis who had hyperglycaemia, produced a significant reduction (P less than 0.001) in blood glucose levels. It is therefore suggested that thiamine supplements be given to cirrhotics with hyperglycaemia, to improve glucose utilization.
Hassan
R
R
Pakistan Medical Research Council Research Centre, Finnah Postgraduate Medical Centre, Karachi.
Qureshi
H
H
Zuberi
S J
SJ
D000328:Adult; D000368:Aged; D005260:Female; D005947:Glucose / Q000378:metabolism; D005951:Glucose Tolerance Test; D006801:Humans; D006943:Hyperglycemia / Q000188:drug therapy* / Q000209:etiology; D008099:Liver / Q000378:metabolism; D008103:Liver Cirrhosis / Q000150:complications / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D013831:Thiamine / Q000627:therapeutic use*
D005947:Glucose; D013831:Thiamine