title: Molecular-biological and immunological properties of ribosomal vaccines.
abstract: Data on the immunological properties and protective action of ribosomal vaccines are reviewed from the point of view of the structural and functional properties of ribosomes. Comparative analyses are presented for ribosomes from Gram-negative and Gram-positive microorganisms, and for ribosomes from prokaryotes and eukaryotes. Special consideration is given to the nature of the protective factors of ribosomal preparations and the mechanisms of ribosomal vaccine immunogenesis.
authors.affiliation: Shemyakin Institute of Bioorganic Chemistry, Academy of Sciences of the USSR, Moscow.
authors.forename: L V
authors.initials: LV
authors.lastname: Nikolaeva
authors.forename: E P
authors.initials: EP
authors.lastname: Savel'ev
mesh_terms: D000818:Animals; D007109:Immunity / Q000187:drug effects; D012335:RNA, Ribosomal / Q000276:immunology; D012270:Ribosomes / Q000276:immunology*; D014612:Vaccines / Q000276:immunology*
chemical_list: D012335:RNA, Ribosomal; D014612:Vaccines