title: Production of 13 plasma proteins by human testicular yolk sac tumor transplanted into nude mice.
abstract: Thirteen human proteins were found in plasma and cystic fluid of mice bearing human testicular yolk sac tumor. Six of them, alpha-fetoprotein, prealbumin, albumin, alpha 1-antitrypsin, hemopexin and transferrin, had been previously demonstrated to be produced by yolk sac tumors. The syntheses of the remaining seven, namely apolipoprotein A1, retinol-binding protein, alpha 2HS-glycoprotein, haptoglobin, apolipoprotein B, C5 component and anti-hemophilic factor, have been demonstrated for the first time.
authors.affiliation: Department of Biochemistry, Hokkaido University School of Medicine, Sapporo, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Nishi
authors.forename: T
authors.initials: T
authors.lastname: Nishita
authors.forename: K
authors.initials: K
authors.lastname: Ohkawa
mesh_terms: D000328:Adult; D000818:Animals; D016632:Apolipoprotein A-I; D001054:Apolipoproteins A / Q000096:biosynthesis; D001055:Apolipoproteins B / Q000096:biosynthesis; D001798:Blood Proteins / Q000096:biosynthesis*; D003182:Complement C5 / Q000096:biosynthesis; D005169:Factor VIII / Q000096:biosynthesis; D005260:Female; D006242:Haptoglobins / Q000096:biosynthesis; D006801:Humans; D007106:Immune Sera / Q000378:metabolism; D008297:Male; D008649:Mesonephroma / Q000378:metabolism*; D051379:Mice; D008819:Mice, Nude; D009363:Neoplasm Proteins / Q000096:biosynthesis; D009368:Neoplasm Transplantation; D012177:Retinol-Binding Proteins / Q000096:biosynthesis; D054839:Retinol-Binding Proteins, Plasma; D013736:Testicular Neoplasms / Q000378:metabolism*
chemical_list: D016632:Apolipoprotein A-I; D001054:Apolipoproteins A; D001055:Apolipoproteins B; D001798:Blood Proteins; D003182:Complement C5; D006242:Haptoglobins; D007106:Immune Sera; D009363:Neoplasm Proteins; D012177:Retinol-Binding Proteins; D054839:Retinol-Binding Proteins, Plasma; D005169:Factor VIII