title: [Acute and chronic effects of vasodilators in a case of chronic recurrent pulmonary embolism].
abstract: A 65-year-old man was admitted to our hospital because of shortness of breath on exertion. As the results of examinations including pulmonary angiography, pulmonary perfusion scan and pulmonary ventilation scan, we diagnosed the case as chronic recurrent pulmonary embolism. Although the patient received thrombolytic therapy by a tissue plasminogen activator (t-PA), there was no noticeable improvement. However, oxygen and vasodilator therapy had marked effective on the hemodynamics. In chronic pulmonary embolism, vasodilators are generally not considered to be effective for improvement of hemodynamics. However, if the acute effects of vasodilators were confirmed, we should try to administer them while paying attention to possible adverse effects.
authors.affiliation: Department of Internal Medicine, National Sanatorium Dohoku Hospital, Asahikawa City, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Ido
authors.forename: N
authors.initials: N
authors.lastname: Hasebe
authors.forename: T
authors.initials: T
authors.lastname: Shimizu
authors.forename: J
authors.initials: J
authors.lastname: Fukuzawa
authors.forename: J
authors.initials: J
authors.lastname: Ohsaki
authors.forename: N
authors.initials: N
authors.lastname: Shimaya
authors.forename: Y
authors.initials: Y
authors.lastname: Fujita
authors.forename: T
authors.initials: T
authors.lastname: Tsuji
authors.forename: Y
authors.initials: Y
authors.lastname: Ohki
authors.forename: E
authors.initials: E
authors.lastname: Sakai
mesh_terms: D000368:Aged; D002908:Chronic Disease; D006439:Hemodynamics; D006801:Humans; D008297:Male; D010102:Oxygen Inhalation Therapy; D011655:Pulmonary Embolism / Q000188:drug therapy* / Q000503:physiopathology; D012008:Recurrence; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000627:therapeutic use*
chemical_list: D014665:Vasodilator Agents; D010959:Tissue Plasminogen Activator