title: [The radioprotective effect of extracts of Archangelica officinalis Hoffm. and Ledum palustre L. on mice].
abstract: A single injection of Archangelica officinalis Hoffm. and Ledum palustre L. extracts to mice 5-15 min before irradiation with a median lethal dose increased their survival rate. The most favourable effect was produced by a combination of the two preparations: by day 30 100% of animals survived after a dose of 6 Gy (LD50/30); 70% survived after a dose of 7.5 Gy (LD90/30), and 25% after a dose of 8 Gy (LD100/12). DMF for the extract mixture was 1.48.
authors.forename: A A
authors.initials: AA
authors.lastname: Narimanov
authors.forename: S N
authors.initials: SN
authors.lastname: Miakisheva
authors.forename: S M
authors.initials: SM
authors.lastname: Kuznetsova
mesh_terms: D000818:Animals; D002588:Cesium Radioisotopes; D004338:Drug Combinations; D005720:Gamma Rays; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000008:administration & dosage / Q000627:therapeutic use*; D011833:Radiation Injuries, Experimental / Q000517:prevention & control*; D011837:Radiation-Protective Agents / Q000627:therapeutic use*
chemical_list: D002588:Cesium Radioisotopes; D004338:Drug Combinations; D010936:Plant Extracts; D011837:Radiation-Protective Agents
vernacular_title: Radiozashchitnoe deĭstvie ékstraktov Archangelica officinalis Hoffm. i Ledum palustre L. na mysheĭ.