Treatment of fetal supraventricular tachycardia with flecainide acetate after digoxin failure.
Transplacentally administered digoxin is the drug of choice for the treatment of fetal supraventricular tachycardia. We describe a case of fetal supraventricular tachycardia associated with fetal hydrops that did not respond to digoxin treatment because of a lack of transplacental passage. In contrast, flecainide acetate crossed the placenta and cured the fetus. The clinical implications of this new treatment are discussed.
Kofinas
A D
AD
Department of Obstetrics and Gynecology, York Hospital, PA 17405.
Simon
N V
NV
Sagel
H
H
Lyttle
E
E
Smith
N
N
King
K
K
D000328:Adult; D004077:Digoxin / Q000627:therapeutic use*; D005260:Female; D005315:Fetal Diseases / Q000188:drug therapy*; D005424:Flecainide / Q000627:therapeutic use*; D006801:Humans; D011247:Pregnancy; D013617:Tachycardia, Supraventricular / Q000188:drug therapy*
D004077:Digoxin; D005424:Flecainide