Deet and permethrin as protectants against malaria-infected and uninfected Anopheles stephensi mosquitoes.
Deet and permethrin were evaluated as protectants against Plasmodium falciparum-infected, P. berghei-infected and uninfected Anopheles stephensi mosquitoes. Deet 50% effective dose (ED50) values were 3.2 micrograms/cm2 for P. falciparum-infected and 1.9 micrograms/cm2 for uninfected mosquitoes; permethrin values were 0.5 micrograms/cm2 and 0.6 micrograms/cm2, respectively. Deet ED50 values were 2.3 micrograms/cm2 for P. berghei-infected and 1.3 micrograms/cm2 for uninfected mosquitoes; the permethrin values were both 0.5 micrograms/cm2. There were no significant differences in the protective efficacy of deet or permethrin between malaria-infected and uninfected An. stephensi mosquitoes.
Robert
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Department of Entomology, Walter Reed Army Institute of Research, Washington, DC 20307-5100.
Schneider
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Wirtz
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D000818:Animals; D000852:Anopheles / Q000469:parasitology*; D003671:DEET; D004305:Dose-Response Relationship, Drug; D007299:Insect Bites and Stings / Q000517:prevention & control; D007302:Insect Repellents; D008288:Malaria / Q000517:prevention & control* / Q000635:transmission; D026023:Permethrin; D010962:Plasmodium berghei; D010963:Plasmodium falciparum; D011722:Pyrethrins; D011817:Rabbits
D007302:Insect Repellents; D011722:Pyrethrins; D003671:DEET; D026023:Permethrin