Revised technique of heterotopic heart transplantation in rabbits.
The technique of heterotopically transplanting a rabbit heart into the abdominal position of a recipient rabbit is discussed. Myocardial preservation, vascular anatomy of the recipient, and general anesthetic considerations are described, as are techniques to avoid anesthetic death, hemorrhage, and paraplegia. Application of these techniques to experimental models of accelerated coronary atherosclerosis and reperfusion injury are suggested.
Dworkin
G H
GH
Department of Surgery, Medical College of Virginia, Richmond 23298.
Eich
D M
DM
Allen
C
C
Wechsler
A S
AS
D000005:Abdomen; D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D016027:Heart Transplantation / Q000009:adverse effects / Q000379:methods*; D008297:Male; D011817:Rabbits; D016042:Transplantation, Heterotopic / Q000379:methods*