Liquid chromatographic determination of acyclovir.
An easy and precise HPLC method was developed to determine acyclovir in liophilized vials and ointments. The described procedure detects guanine which can be present in raw material as a synthetic contaminant or a degradation product. The method proved to be simple and accurate.
Marini
D
D
Laboratorio Chimico Centrale delle Dogane, Roma.
Pollino
G
G
Balestrieri
F
F
D000212:Acyclovir / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D009824:Ointments; D012996:Solutions; D013056:Spectrophotometry, Ultraviolet
D009824:Ointments; D012996:Solutions; D000212:Acyclovir