title: [Pituitary apoplexy and empty sella].
abstract: Pituitary apoplexy (PA) is currently considered as one of the causes of empty sella (ES). However, in most reported cases the diagnosis of PA was based on anamnesis. A prospective study of three patients diagnosed during the PA episode was carried out. Periodical evaluations of hormone concentrations and cerebral computed tomography images were carried out. Initially, the three patients had a global anterior pituitary developed ES within 6 and 18 months. Surgical therapy was not undertaken in any case. Owing to the rarity of the disease definitive conclusions are difficult to obtain; however, the present study suggests that after an episode of PA global anterior pituitary failure develops, with subsequent ES. Early medical therapy with glucocorticoids can avoid surgical therapy.
authors.affiliation: Sección de Endocrinología, Hospital General Vall d'Hebron, Barcelona.
authors.forename: J
authors.initials: J
authors.lastname: Montalbán
authors.forename: R
authors.initials: R
authors.lastname: Simó
authors.forename: J
authors.initials: J
authors.lastname: Sumalla
authors.forename: M
authors.initials: M
authors.lastname: Tintoré
authors.forename: J L
authors.initials: JL
authors.lastname: Fernández
authors.forename: A
authors.initials: A
authors.lastname: Codina
mesh_terms: D000368:Aged; D003907:Dexamethasone / Q000627:therapeutic use; D004652:Empty Sella Syndrome / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010899:Pituitary Apoplexy / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed
chemical_list: D003907:Dexamethasone
vernacular_title: Apoplejía hipofisaria y silla turca vacía.