Validation of the Glasgow Meningococcal Septicemia Prognostic Score: a 10-year retrospective survey.
OBJECTIVE
To derive performance characteristics for the Glasgow Meningococcal Septicemia Prognostic Score (GMSPS).


METHODS
Retrospective case-note study.


METHODS
Two children's hospitals with Regional Intensive Care Unit.


METHODS
One hundred twenty-three children with proven meningococcal septicemia (some with concurrent meningitis) from January 1, 1977 to December 31, 1986.


RESULTS
All 14 children who died after arrival scored greater than or equal to 8 either on admission (n = 8) or afterward (n = 6). Of 109 survivors, five scored greater than or equal to 8 (two were postictal at the time of scoring). A GMSPS of greater than or equal to 10 at or after admission predicted death with sensitivity 100%, specificity 98%, and positive predictive value of 88%; for GMSPS of both greater than or equal to 8 or 9, the values were 100%, 95%, and 74%, respectively.


CONCLUSIONS
The GMSPS is a rapid clinical score that performs well in identifying children with poor prognosis who might benefit from early intensive care. It should be studied prospectively and compared with other scoring systems.
Thomson
A P
AP
Institute of Child Health, Royal Liverpool Childrens' Hospitals, UK.
Sills
J A
JA
Hart
C A
CA
D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008589:Meningococcal Infections / Q000175:diagnosis*; D009345:Neisseria meningitidis; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D018805:Sepsis / Q000175:diagnosis*; D012720:Severity of Illness Index