title: Phenotypic, embryonic, and neonatal effects of a gene for sex-linked imperfect albinism (Sal-s) in chickens.
abstract: Gross phenotypic observations, histology, and tissue culture showed that the gene for sex-linked imperfect albinism that occurred at the University of Saskatchewan (Sal-s), allows a small amount of melanin pigment to be deposited in eyes and feathers. Melanin pigment accumulates in retinal pigment epithelial and cultured neural crest cells, but neural crest cells pigmenting the feathers transfer their pigment as it is produced, and this is seen as a constant amount of color in successive generations of feathers. Despite differences from early reports, it would appear that the phenotype produced by Sal-s is essentially the same as that produced by other Sal mutations. Albinos have a high incidence of lesions in the regions of the navel, the hocks, and the nares, similar to those associated with other hypomelanic mutations in the chicken. Yolk contents appear to be used more slowly by albinos late in incubation. The increased size of the yolk sacs probably contributes directly to producing the navel lesions and indirectly to variation in hatch weight. Albinos have small bursae of Fabricius, reduced hatchability, and early growth.
authors.affiliation: Department of Animal and Poultry Science, University of Saskatchewan, Saskatoon, Canada.
authors.forename: F G
authors.initials: FG
authors.lastname: Silversides
authors.forename: R D
authors.initials: RD
authors.lastname: Crawford
mesh_terms: D000818:Animals; D001835:Body Weight; D002060:Bursa of Fabricius / Q000196:embryology / Q000473:pathology; D002642:Chick Embryo; D002645:Chickens; D005260:Female; D008040:Genetic Linkage; D008297:Male; D009929:Organ Size; D010641:Phenotype; D016116:Piebaldism / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D011201:Poultry Diseases / Q000235:genetics* / Q000473:pathology; D016038:Skin Transplantation / Q000662:veterinary; D015017:Yolk Sac / Q000473:pathology