[Radiation-induced neurosarcoma. Clinical, histological and immunohistochemistry aspects].
The authors report on a case of radiation-induced malignant Triton tumor eg malignant schwannoma with rhabdomyoblastic differentiation). The tumor was situated in the brachial plexus of a patient who had received irradiation therapy 20 years previously for breast carcinoma. Pathological and immunohistological features have been described: coexpression of PS100, vimentin and desmin indicate a common neuroectodermic origin. A review of the literature has been presented in order to evaluate the diagnostic and prognostic characteristics of this unusual tumor and its relationship to neurofibromatosis.
Beuvon
F
F
Laboratoire d'anatomie pathologique, institut Curie, Paris, France.
Criscuolo
J L
JL
Salmon
R J
RJ
Laurent
M
M
D001917:Brachial Plexus; D001943:Breast Neoplasms / Q000532:radiotherapy; D003893:Desmin; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis* / Q000473:pathology; D009455:Neurofibroma / Q000175:diagnosis* / Q000473:pathology; D011379:Prognosis; D011879:Radiotherapy Dosage; D014746:Vimentin
D003893:Desmin; D014746:Vimentin
Neurosarcome radio-induit. Aspects clinique, histologique et immunohistochimique.