Computerized analysis of episodic changes in fetal heart rate variation in early labor.
Fetal heart rate variation in early labor was measured by computerized analysis in cyclic episodes of low or high variation in 136 women at 37 to 42 weeks' gestation. The amplitude (mean +/- SE) in episodes of low variation was 20.6 +/- 0.4 milliseconds; in high variation it was 57.3 +/- 1.1 milliseconds. The duration (mean +/- SE) of low episodes (24.3 +/- 1.3 minutes) was less than that of high episodes (45.1 +/- 2.7 minutes) but was sometimes greater than 1 hour. In episodes of low variation the amplitude was less than 5 beats/min long term in 11% and less than 2.5 milliseconds (pulse intervals) short term in 8%; these measures would be predictive of intrauterine death if persistent before birth. We conclude that the use of decreased fetal heart rate variation as a diagnostic sign of acute fetal hypoxemia in labor is incorrect, because changes of this size occur randomly as a consequence of fetal sleep states. There was no significant correlation between fetal heart rate variation over the last hour of labor and umbilical arterial base deficit on delivery.
Dawes
G S
GS
Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Oxford, England.
Rosevear
S K
SK
Pello
L C
LC
Moulden
M
M
Redman
C W
CW
D000328:Adult; D002940:Circadian Rhythm; D003201:Computers; D005260:Female; D005323:Fetal Monitoring; D006340:Heart Rate, Fetal; D006801:Humans; D007747:Labor Stage, First / Q000502:physiology; D007748:Labor Stage, Second / Q000502:physiology; D007743:Labor, Obstetric / Q000502:physiology*; D011247:Pregnancy