[Lipid profiles of breast cancer cell lines: proton nuclear magnetic resonance spectroscopy].
Nuclear magnetic resonance spectroscopy was performed on breast cancer cell lines MCF-7, MDA-MB231 and T47D. Proton spectra showed discrepancies of lipid quantity in the different lines. The high resolution lines of lipids were not as intense in the membrane preparations. These results show the potential of NMR spectroscopy to study the involvement of membrane lipids in proliferation, metastasis or drug resistance process.
Le Moyec
L
L
Laboratoire de RMN, Hôpital Saint-Louis, Paris.
Eugène
M
M
Gauvillé
C
C
Tatoud
R
R
Ouvrard
B N
BN
Calvo
F
F
D000230:Adenocarcinoma / Q000737:chemistry* / Q000473:pathology; D001943:Breast Neoplasms / Q000737:chemistry* / Q000473:pathology; D002455:Cell Division; D002461:Cell Line, Transformed; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008563:Membrane Lipids / Q000032:analysis*
D008563:Membrane Lipids
Profils lipidiques de lignées de cancer du sein: spectrométrie par résonance magnétique nucléaire du proton.