A computer program for the estimation of kinetic parameters of membrane currents based on the Gauss-Newton method.
A computer program based on the Gauss-Newton method was developed for the Hodgkin-Huxley estimation of kinetic parameters of membrane currents recorded in voltage-clamp experiments. Fast potassium current of land snail neurons was estimated, and found to be in agreement with literature reports.
Grave de Peralta
R
R
National Center for Scientific Research, Neuroscience Center, Havana, Cuba.
Hernández
J L
JL
Castellanos
M
M
Garateix
A
A
D000465:Algorithms; D000818:Animals; D007700:Kinetics; D008432:Mathematical Computing; D008564:Membrane Potentials / Q000502:physiology; D015221:Potassium Channels / Q000378:metabolism*; D012908:Snails; D012984:Software
D015221:Potassium Channels