Induction of fetal lung maturation with intra-amniotic thyroxine in multiple pregnancy.
Two premature triplet pregnancies underwent repeated treatment aimed at acceleration of individual fetal lung maturity while administering intravenous tocolytic treatment. From the early third trimester, repeated amniocenteses were used for intra-amniotic administration of thyroxine to each sac, while the individual fetal lung maturation rate was determined by surfactant microviscosity until lung maturity was achieved.
Dan
U
U
Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
Barkai
G
G
Reichman
B
B
Goldman
B
B
Mashiach
S
S
D000328:Adult; D000649:Amniocentesis; D005260:Female; D005325:Fetal Organ Maturity; D006801:Humans; D008168:Lung / Q000187:drug effects* / Q000196:embryology / Q000378:metabolism; D007752:Obstetric Labor, Premature / Q000517:prevention & control; D011247:Pregnancy; D011272:Pregnancy, Multiple; D011663:Pulmonary Surfactants / Q000096:biosynthesis / Q000187:drug effects; D012312:Ritodrine / Q000627:therapeutic use; D013974:Thyroxine / Q000627:therapeutic use*; D014310:Triplets
D011663:Pulmonary Surfactants; D012312:Ritodrine; D013974:Thyroxine