Total organic carbon measurement as a substitute for the USP oxidizable substances test.
The insensitivity and variability of response of the USP Oxidizable Substances Test for waters are investigated. Instrumental measurement of Total Organic Carbon (TOC) is described, and the method is compared with the Oxidizable Substances Test. Pharmaceutical factory measurements of TOC in various water systems are discussed.
Crane
G A
GA
Rosemount Analytical, Inc., Dohrmann Division, Santa Clara, California.
Mittleman
M W
MW
Stephan
M
M
D002244:Carbon / Q000032:analysis; D002245:Carbon Dioxide / Q000032:analysis; D011196:Potassium Permanganate; D012015:Reference Standards; D013055:Spectrophotometry, Infrared; D013678:Technology, Pharmaceutical / Q000592:standards*; D014481:United States; D014867:Water / Q000032:analysis / Q000592:standards*
D011196:Potassium Permanganate; D014867:Water; D002245:Carbon Dioxide; D002244:Carbon