Risk evaluation in a small series of transabdominal chorionic villus sampling.
Previous reports have suggested that the fetal loss rate with transcervical chorionic villus sampling was high in the initial 100-300 procedures performed. In a consecutive series of 155 patients with first-trimester transabdominal chorionic villus sampling (CVS), we observed a total fetal loss rate of 8.4%, and loss rate not attributable to induced abortion or cytogenetic abnormality of 3.2%. Our results demonstrate that transabdominal CVS in the first trimester of pregnancy is a safe method of prenatal diagnosis.
Bergman
B
B
Department of Obstetrics and Gynecology, Central Hospital, Skövde, Sweden.
Claesson
U
U
Mark
J
J
D000005:Abdomen; D000022:Abortion, Spontaneous / Q000453:epidemiology* / Q000209:etiology; D000328:Adult; D015193:Chorionic Villi Sampling / Q000009:adverse effects* / Q000379:methods / Q000592:standards; D002869:Chromosome Aberrations / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics; D025063:Chromosome Disorders; D005069:Evaluation Studies as Topic; D005260:Female; D005865:Gestational Age; D006801:Humans; D007621:Karyotyping; D008423:Maternal Age; D011247:Pregnancy; D011256:Pregnancy Outcome; D011261:Pregnancy Trimester, First; D012307:Risk Factors