[Intravaginal administration of CDDP for adenocarcinoma].
Single vaginal administration of CDDP was done in a case of adenocarcinoma when relapse in the vaginal stump followed surgery for uterine corpus carcinoma. A tumor the size of a large fingertip in the vaginal stump was completely eliminated via 15-time (75 mg) CDDP vaginal administration, suggesting that this treatment was effective against adenocarcinoma. The only side effect over the whole body was slight pain developing in the external genitalia.
Nakayama
K
K
Dept. of Obstetrics and Gynecology, Tachikawa Kyosa Hospital, Japan.
Nozawa
S
S
Yamaguchi
M
M
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary; D000282:Administration, Intravaginal; D002945:Cisplatin / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D014594:Uterine Neoplasms / Q000473:pathology / Q000601:surgery; D014625:Vaginal Neoplasms / Q000188:drug therapy* / Q000556:secondary
D002945:Cisplatin