title: [Effect of adaptation to periodic hypoxia on post-infarction fall of blood pressure and hyperactivation of the endothelium].
abstract: Acute stress concomitant to the experimental myocardial infarction has induced endothelial hyperactivation of the rat aorta exhibited in an increase of inhibition of norepinephrine-induced contractions of vascular smooth muscle, enhanced endothelium-dependent relaxation correlating with a fall of systemic blood pressure. Preliminary adaptation of rats to intermittent hypobaric hypoxia greatly prevented the stress-induced endothelial hyperactivation and beneficially affected the postinfarction time course of blood pressure.
authors.forename: E B
authors.initials: EB
authors.lastname: Manukhina
authors.forename: A V
authors.initials: AV
authors.lastname: Lapshin
authors.forename: F Z
authors.initials: FZ
authors.lastname: Meerson
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology*; D000818:Animals; D001011:Aorta / Q000503:physiopathology*; D001794:Blood Pressure / Q000502:physiology*; D004195:Disease Models, Animal; D004730:Endothelium, Vascular / Q000503:physiopathology*; D006973:Hypertension / Q000517:prevention & control*; D000860:Hypoxia / Q000209:etiology / Q000503:physiopathology*; D008297:Male; D009203:Myocardial Infarction / Q000150:complications / Q000503:physiopathology*; D010507:Periodicity; D051381:Rats; D011919:Rats, Inbred Strains
vernacular_title: Vliianie adaptatsii k periodicheskoĭ gipoksii na postinfarktnoe padenie davleniia i giperaktivatsiiu éndoteliia.