[The effect of low-dose whole-body gamma-irradiation on the activity of enzyme systems in the rat adrenal medulla].
A study was made of the pattern of changes in histochemical indices of key enzymes of the tricarboxylic acid cycle (succinate dehydrogenase) and glycolysis (lactate dehydrogenase) as well as of catecholamines (monoamine oxidase) in cells of the adrenal medulla of young and adult albino rats subjected to external whole-body gamma-irradiation with doses of 0.5 and 1.0 Gy (dose-rate of 2.7 X 10(-4) Gy/s). Radiosensitivity of the enzyme systems under study in the adrenal gland cells of young animals was higher than in that of adults. Changes of their levels in different periods of observation were mainly of phase nature and indicated the development of adaptation syndrome in the animal organism.
Ambros'ev
A P
AP
Shostak
Iu A
IuA
D000313:Adrenal Medulla / Q000201:enzymology / Q000528:radiation effects*; D000375:Aging / Q000378:metabolism; D000818:Animals; D003037:Cobalt Radioisotopes; D005720:Gamma Rays; D007770:L-Lactate Dehydrogenase / Q000378:metabolism*; D008297:Male; D008995:Monoamine Oxidase / Q000378:metabolism*; D011829:Radiation Dosage; D051381:Rats; D011919:Rats, Inbred Strains; D013385:Succinate Dehydrogenase / Q000378:metabolism*; D014916:Whole-Body Irradiation
D003037:Cobalt Radioisotopes; D007770:L-Lactate Dehydrogenase; D013385:Succinate Dehydrogenase; D008995:Monoamine Oxidase
Vliianie obshchego gamma-oblucheniia v malykh dozakh na aktivnost' nekotorykh fermenty sistem mozgovogo veshchestva nadpochechnikov krysy.