title: Comparative study of semen in diabetic and healthy men.
abstract: This study examines the consequences of diabetes on male reproductive function. We have studied a group of 18 diabetics (15 type I, 3 type II) age 24 to 40 years (mean 34 +/- 5.3) with duration of diabetes from 2 to 30 years (mean 11.8 +/- 8.3). This group was compared to 20 semen donors. In diabetics higher sperm (p = 0.0063) and round cell (p = 0.031) concentrations/ml as well as a higher total spermatozoa count (p = 0.023) were observed. The percentage of abnormal sperms were also higher. None of the couples had consulted for sterility and they had a mean of 2 children. In this group of patients, diabetes was not a cause of subfertility. Specific spermiological alteration in diabetics might reflect a testicular damage secondary to their diabetes or disease.
authors.affiliation: Service d'Endocrinologie, Hôpital Central, Strasbourg, France.
authors.forename: F
authors.initials: F
authors.lastname: Vignon
authors.forename: A
authors.initials: A
authors.lastname: Le Faou
authors.forename: D
authors.initials: D
authors.lastname: Montagnon
authors.forename: A
authors.initials: A
authors.lastname: Pradignac
authors.forename: C
authors.initials: C
authors.lastname: Cranz
authors.forename: P
authors.initials: P
authors.lastname: Winiszewsky
authors.forename: M
authors.initials: M
authors.lastname: Pinget
mesh_terms: D000328:Adult; D003920:Diabetes Mellitus / Q000503:physiopathology*; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology; D004542:Ejaculation; D006801:Humans; D008297:Male; D012016:Reference Values; D012661:Semen / Q000166:cytology / Q000502:physiology*; D013076:Sperm Count