title: [Structure of tryptic fragments of a neurotoxin from black widow spider venom].
abstract: The N-terminal amino acid sequence of a neurotoxin from the venom of Latrodectus mactans tredecimguttatus (alpha-latrotoxin) was determined. Latrotoxin was subjected to the tryptic cleavage and total or partial amino acid sequences of 25 peptides were established. In total the tryptic fragments contained 252 amino acid residues. Essential structural information on cloning of the latrotoxin structural gene was obtained.
authors.forename: T M
authors.initials: TM
authors.lastname: Volkova
authors.forename: T G
authors.initials: TG
authors.lastname: Galkina
authors.forename: A B
authors.initials: AB
authors.lastname: Kudelin
authors.forename: E V
authors.initials: EV
authors.lastname: Grishin
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001740:Black Widow Spider; D002851:Chromatography, High Pressure Liquid; D004591:Electrophoresis, Polyacrylamide Gel; D005796:Genes; D008969:Molecular Sequence Data; D010449:Peptide Mapping; D013111:Spider Venoms / Q000235:genetics*; D014357:Trypsin
chemical_list: D013111:Spider Venoms; C020763:alpha-latrotoxin; D014357:Trypsin
vernacular_title: Struktura tripticheskikh fragmentov neĭrotoksina iz iada pauka karakurta.