title: [Polychlorobiphenyls in human milk, adipose tissue, plasma and umbilical cord blood; levels and correlates].
abstract: In a longitudinal study involving 17 women, PCB concentrations (PCBs 138, 153 and 180) were determined in cord blood (17 newborns), breast milk (10 women), maternal adipose tissue (8 women), maternal plasma collected during the last trimester of pregnancy (17 women) and maternal plasma collected 10 days post partum (7 women). Significant correlations were found (p less than 0.05) between PCB levels in cord blood, breast milk and adipose tissue and maternal plasma collected before birth, and between breast milk and maternal plasma collected post partum. In 2 vegetarian women the PCB levels in maternal plasma and cord blood were significantly lower than in the other women (p less than 0.05). If in future studies the PCB levels observed prove to be detrimental to child development, these correlations may offer the possibility of identifying a group of newborns at risk for occurrence of developmental defects due to PCB exposure before birth.
authors.affiliation: Academisch Ziekenhuis Rotterdam-Sophia Kinderziekenhuis, afd. Kindergeneeskunde, subafd. Pasgeborenen.
authors.forename: A H
authors.initials: AH
authors.lastname: van Kaam
authors.forename: C
authors.initials: C
authors.lastname: Koopman-Esseboom
authors.forename: E J
authors.initials: EJ
authors.lastname: Sulkers
authors.forename: P J
authors.initials: PJ
authors.lastname: Sauer
authors.forename: C G
authors.initials: CG
authors.lastname: van der Paauw
authors.forename: L G
authors.initials: LG
authors.lastname: Tuinstra
mesh_terms: D000273:Adipose Tissue / Q000737:chemistry*; D000293:Adolescent; D000328:Adult; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D005506:Food Contamination; D006801:Humans; D007231:Infant, Newborn; D008137:Longitudinal Studies; D008895:Milk, Human / Q000737:chemistry*; D011078:Polychlorinated Biphenyls / Q000032:analysis* / Q000097:blood; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects
chemical_list: D011078:Polychlorinated Biphenyls
vernacular_title: Polychloorbifenylen (PCB's) in moedermelk, vetweefsel, plasma en navelstrengbloed; gehalten en correlaties.