title: Research note: bioavailability of copper in cupric oxide, cuprous oxide, and in a copper-lysine complex.
abstract: Young chicks were used in a 2-wk feeding study to evaluate Cu bioavailability (relative to CuSO4.5H2O used as a reference standard) in analytical grade CuO, Cu2O, and in a feed-grade Cu-lysine complex. A basal corn and soybean meal diet was formulated to contain 290 mg Cu/kg, and graded levels (0, 75, and 150 mg/kg) of supplemental Cu were added from each Cu source. Based upon accumulation of Cu in the liver, Cu2O and Cu-lysine furnished Cu as efficiently as CuSO4.5H2O, but CuO provided no bioavailable Cu to the chicks.
authors.affiliation: Department of Animal Sciences, University of Illinois, Urbana 61801.
authors.forename: D H
authors.initials: DH
authors.lastname: Baker
authors.forename: J
authors.initials: J
authors.lastname: Odle
authors.forename: M A
authors.initials: MA
authors.lastname: Funk
authors.forename: T M
authors.initials: TM
authors.lastname: Wieland
mesh_terms: D000818:Animals; D001682:Biological Availability; D002645:Chickens / Q000378:metabolism*; D003300:Copper / Q000493:pharmacokinetics*; D008099:Liver / Q000378:metabolism; D008239:Lysine / Q000378:metabolism*; D008297:Male
chemical_list: D003300:Copper; D008239:Lysine; C000520:cuprous oxide; C030973:cupric oxide