[Changes in the osmotic resistance of the erythrocytes in thermal trauma and the role of free-radical oxidation].
Reduced erythrocyte osmotic resistance against the background of elevated blood level of TBA-reactive products was recorded in experimental thermic injury (of IIIa-IIIb degree, involving 15-20 per cent of the body surface). Under the influence of alpha-tocopherol, parallel with the restriction of free-radical oxidation (FRO) activity, there was a rise in erythrocyte membrane osmotic resistance. FRO participation in the mechanisms of reduced erythrocyte osmotic resistance in thermic injury is discussed.
Bekiarova
G
G
Kozarev
I
I
D000208:Acute Disease; D000818:Animals; D002056:Burns / Q000097:blood* / Q000188:drug therapy; D004353:Drug Evaluation, Preclinical; D005609:Free Radicals; D008297:Male; D009996:Osmotic Fragility / Q000187:drug effects; D010084:Oxidation-Reduction / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors; D014810:Vitamin E / Q000627:therapeutic use
D005609:Free Radicals; D014810:Vitamin E
Promeni v osmotichnata rezistentnost na eritrotsitite pri termichna travma i roliata na svobodnoradikalnoto okislenie.