title: Molecular size and symmetry of Pseudomonas aeruginosa catabolic ornithine carbamoyltransferase. An X-ray crystallography analysis.
abstract: The catabolic ornithine carbamoyltransferase (EC 2.1.3.3) from Pseudomonas aeruginosa, that shows allosteric behaviour, and a mutant version of this enzyme has been crystallized in several different crystal forms. All of these have been characterized by X-ray diffraction methods. A 4.5 A resolution data set has been collected on a triclinic crystal. Analysis of the data using the self-rotation function shows that 12 monomers associate to form a particle with cubic 23 point group symmetry.
authors.affiliation: Institut de Physique, Université de Liège, Belgium.
authors.forename: S
authors.initials: S
authors.lastname: Marcq
authors.forename: A
authors.initials: A
authors.lastname: Diaz-Ruano
authors.forename: P
authors.initials: P
authors.lastname: Charlier
authors.forename: O
authors.initials: O
authors.lastname: Dideberg
authors.forename: C
authors.initials: C
authors.lastname: Tricot
authors.forename: A
authors.initials: A
authors.lastname: Piérard
authors.forename: V
authors.initials: V
authors.lastname: Stalon
mesh_terms: D046911:Macromolecular Substances; D008961:Models, Structural; D009954:Ornithine Carbamoyltransferase / Q000737:chemistry* / Q000302:isolation & purification; D011487:Protein Conformation; D011550:Pseudomonas aeruginosa / Q000201:enzymology*; D014961:X-Ray Diffraction / Q000379:methods
chemical_list: D046911:Macromolecular Substances; D009954:Ornithine Carbamoyltransferase