title: The effect of a chlorhexidine rinse on the incidence of alveolar osteitis following the surgical removal of impacted mandibular third molars.
abstract: A prospective randomized double-blind placebo-controlled study was conducted with 139 patients (278 bilaterally impacted mandibular third molars) to determine the effect of a perioperative 0.12% chlorhexidine gluconate rinse on the incidence of alveolar osteitis following surgical removal of impacted mandibular third molars. A statistically significant 60% reduction in the incidence of alveolar osteitis was obtained in the chlorhexidine group compared with the placebo group. In most subgroups analyzed, chlorhexidine was associated with at least a 50% reduction in alveolar osteitis compared with control groups.
authors.affiliation: Department of Oral and Maxillofacial Surgery, College of Dentistry, Ohio State University, Columbus 43210.
authors.forename: P E
authors.initials: PE
authors.lastname: Larsen
mesh_terms: D000293:Adolescent; D000328:Adult; D002710:Chlorhexidine / Q000627:therapeutic use*; D004311:Double-Blind Method; D004368:Dry Socket / Q000453:epidemiology / Q000517:prevention & control*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008964:Molar, Third; D011446:Prospective Studies; D014081:Tooth Extraction; D014095:Tooth, Impacted / Q000601:surgery
chemical_list: D002710:Chlorhexidine