title: [Long term follow-up of non-symptomatic HBsAg carriers].
abstract: 232 asymptomatic HBsAg carriers were controlled between May/1986 and May/1990. The were detected in our blood bank between 1974 and 1976 or during pregnancy or delivery period after 1981. 23 of 232 (10%) became negative during the follow-up, this happening more frequently in carriers after 5 years of follow-up. Only 2 of 209 carriers with HBsAg were HBeAg positive and 1 of these was also DNA-VHB positive. None of the HBeAg negative carriers showed DNA-VHB; only 5 had increased transaminases. 7 were anti-VHC positive, these individuals experiencing more frequent increases in transaminases. The results of this study suggests that the determination of transaminases, viral activity markers, anti-HD, anti-VHC in HBsAg carriers are enough to identify those with hepatic disease.
authors.affiliation: Sección de Hepatología, Hospital General Universitario Vall d'Hebrón, Universidad Autónoma, Barcelona.
authors.forename: A
authors.initials: A
authors.lastname: González
authors.forename: V
authors.initials: V
authors.lastname: Vargas
authors.forename: J M
authors.initials: JM
authors.lastname: Hernández-Sánchez
authors.forename: M
authors.initials: M
authors.lastname: Cortina
authors.forename: D
authors.initials: D
authors.lastname: Pelegrí
authors.forename: J C
authors.initials: JC
authors.lastname: López-Talavera
authors.forename: J
authors.initials: J
authors.lastname: Genescá
authors.forename: R
authors.initials: R
authors.lastname: Jardí
authors.forename: R
authors.initials: R
authors.lastname: Esteban
authors.forename: J
authors.initials: J
authors.lastname: Guardia
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002353:Carrier State / Q000276:immunology*; D005260:Female; D005500:Follow-Up Studies; D006509:Hepatitis B / Q000276:immunology*; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D006514:Hepatitis B Surface Antigens
vernacular_title: Seguimiento a largo plazo de portadores asintomáticos de HBsAg.