Coeliac disease, folic acid deficiency and epilepsy with cerebral calcifications.
Two cases of focal occipital epilepsy with cerebral calcifications poorly responsive to antiepileptic treatment are described. In both cases coeliac disease was diagnosed and folic acid deficiency documented. A gluten-free diet and a brief supplementation with folic acid lead to a complete EEG and clinical normalization in one case and to a significant improvement of EEG and seizure control in the other.
Ventura
A
A
Department of Paediatrics, University Hospital, Istituto per l'Infanzia Burlo Garofolo, Italy.
Bouquet
F
F
Sartorelli
C
C
Barbi
E
E
Torre
G
G
Tommasini
G
G
D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage; D001928:Brain Diseases, Metabolic / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D002114:Calcinosis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D002446:Celiac Disease / Q000150:complications* / Q000175:diagnosis / Q000178:diet therapy; D002675:Child, Preschool; D004828:Epilepsies, Partial / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D005492:Folic Acid / Q000008:administration & dosage; D005494:Folic Acid Deficiency / Q000175:diagnosis / Q000178:diet therapy / Q000209:etiology*; D005983:Glutens / Q000008:administration & dosage; D006801:Humans; D009778:Occipital Lobe
D000927:Anticonvulsants; D005983:Glutens; D005492:Folic Acid