title: [Changes in ultrastructure and actomyosin complex of cardiomyocytes in experimental hypergravitation].
abstract: There were studied the cardiomyocyte ultrastructure, contractile function, actomyosin complex composition and property of the rat ventricular myocardium after repeated gravitational overloading and following rest. In the hypergravitation period cardiomyocyte changes carry destructive character or are regenerative processes manifestation. They are comparable with myocardial contractile function state and with displacements in molecular structure of myofibrillar apparatus. At rest conditions the liquidation of cardiomyocytes destructive changes falls behind the normalization of contractile and regulatory cells of physico-chemical characteristics. The possible reasons of this phenomenon are discussed.
authors.forename: M O
authors.initials: MO
authors.lastname: Nikogosova
authors.forename: M A
authors.initials: MA
authors.lastname: Kaĭfadzhian
authors.forename: S B
authors.initials: SB
authors.lastname: Barinian
authors.forename: A A
authors.initials: AA
authors.lastname: Akopian
mesh_terms: D000205:Actomyosin / Q000032:analysis*; D000818:Animals; D004586:Electrophoresis; D005260:Female; D006112:Gravitation; D008297:Male; D009200:Myocardial Contraction; D009206:Myocardium / Q000166:cytology / Q000473:pathology / Q000648:ultrastructure*; D051381:Rats; D012038:Regeneration; D012146:Rest
chemical_list: D000205:Actomyosin
vernacular_title: Izmeneniia ul'trastruktury i aktomiozinovogo kompleksa kardiomiotsitov pri éksperimental'noĭ gipergravitatsii.