Perspectives in colorectal cancer.
This paper presents an overview of recent developments pertaining to colorectal adenocarcinoma. It is aimed toward the practicing clinician. Topics discussed include epidemiologic observations; genetic predispositions; molecular biology findings; screening and early detection programs; endoscopy; principles of surgical resection; laser and radioimmunoguided surgery; staging; selection of patients for adjuvant chemotherapy; and considerations regarding biologic response modifiers and pain control in the advanced-disease setting.
Herrera
L
L
Division of Surgical Oncology, Medical Center of Delaware, Wilmington.
Luna
P
P
Villarreal
J R
JR
Brown
M
M
Sorrentino
J
J
Khalek
Y
Y
D000230:Adenocarcinoma; D014408:Biomarkers, Tumor; D015179:Colorectal Neoplasms; D003131:Combined Modality Therapy; D016147:Genes, Tumor Suppressor; D006801:Humans; D008403:Mass Screening; D009367:Neoplasm Staging; D009857:Oncogenes
D014408:Biomarkers, Tumor