Purpura fulminans in three cases of early-onset neonatal group B streptococcal meningitis.
The diagnosis of purpura fulminans was associated with three cases of early-onset group B beta-hemolytic streptococcal (GBS) disease. All three infants had confirmed bacterial disease, extensive purpuric lesions involving the extremities, and laboratory evidence of a consumptive coagulopathy. All three children survived but had markedly compromised neurologic outcomes. Purpura fulminans has not been previously reported with early-onset GBS disease.
Lynn
N J
NJ
Department of Pediatrics, Albert B. Chandler Medical Center, University of Kentucky, Lexington.
Pauly
T H
TH
Desai
N S
NS
D004211:Disseminated Intravascular Coagulation / Q000150:complications / Q000209:etiology*; D005385:Fingers / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008581:Meningitis / Q000150:complications* / Q000382:microbiology; D009336:Necrosis; D011693:Purpura / Q000150:complications / Q000209:etiology*; D013290:Streptococcal Infections / Q000150:complications* / Q000382:microbiology; D013292:Streptococcus agalactiae / Q000302:isolation & purification*; D013577:Syndrome; D014034:Toes / Q000473:pathology