Acute sarcocystosis-like disease in a dog.
Two of 8 littermate Rottweiler dogs developed persistent diarrhea at 6.5 weeks of age. Dog 1 was euthanatized at 14 weeks of age and had hepatitis characterized by necrosis and mixed leukocyte infiltrations in association with a previously unrecognized Sarcocystis-like protozoon. The organism was free in the hepatocyte cytoplasm without a parasitophorous vacuole, had divided by schizogony, and stained with anti-Sarcocystis serum, but did not stain with anti-Toxoplasma gondii or anti-Neospora caninum serum in an immunohistochemical test. Dog 2 was euthanatized at 10 weeks of age. This dog had large necrotic, hemorrhagic mesenteric lymph nodes. Numerous T gondii tachyzoites were observed in association with these lesions. The organism divided by endodyogeny and stained specifically with anti-T gondii serum.
Dubey
J P
JP
Livestock and Poultry Sciences Institute, USDA, Beltsville, MD 20705.
Cosenza
S F
SF
Lipscomb
T P
TP
Topper
M J
MJ
Speer
C A
CA
Hoban
L D
LD
Davis
S W
SW
Kincaid
A L
AL
Seely
J C
JC
Marrs
G E
GE
D000208:Acute Disease; D000818:Animals; D004283:Dog Diseases / Q000469:parasitology* / Q000473:pathology; D004285:Dogs; D005260:Female; D008099:Liver / Q000469:parasitology / Q000473:pathology; D008198:Lymph Nodes / Q000469:parasitology / Q000473:pathology; D008297:Male; D012523:Sarcocystosis / Q000473:pathology / Q000662:veterinary*; D014124:Toxoplasmosis, Animal