title: Structure of Lisch nodules in neurofibromatosis type 1.
abstract: Postmortem examination of the eyes of a patient with neurofibromatosis Type I was performed by light and electronmicroscopy. Lisch nodules were examined and found to consist of a condensation of spindle cells on the anterior iris surface. When nodules were pigmented an underlying stromal naevus was present. Lisch nodules are confirmed as being of melanocytic origin.
authors.affiliation: Tennent Institute, Department of Ophthalmology, Western Infirmary, Glasgow, UK.
authors.forename: T H
authors.initials: TH
authors.lastname: Williamson
authors.forename: A
authors.initials: A
authors.lastname: Garner
authors.forename: A T
authors.initials: AT
authors.lastname: Moore
mesh_terms: D006801:Humans; D007223:Infant; D007498:Iris / Q000648:ultrastructure*; D015811:Iris Neoplasms / Q000648:ultrastructure*; D008297:Male; D009456:Neurofibromatosis 1 / Q000473:pathology*; D009508:Nevus, Pigmented / Q000648:ultrastructure*