Tranexamic acid treatment of hemothorax in two patients with malignant mesothelioma.
Patients with malignant mesothelioma may present with hemothorax. We used a combination of oral and intrapleural tranexamic acid to treat two patients with this severe complication. Initiation of treatment with this potent anti-fibrinolytic drug resulted in rapid reduction of bleeding and of transfusion requirements.
De Boer
W A
WA
Academic Medical Center, Amsterdam, The Netherlands.
Koolen
M G
MG
Roos
C M
CM
Ten Cate
J W
JW
D000368:Aged; D001777:Blood Coagulation; D005260:Female; D005342:Fibrinolysis; D006491:Hemothorax / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000150:complications*; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000150:complications*; D014148:Tranexamic Acid / Q000627:therapeutic use*
D014148:Tranexamic Acid