[Bladder involvement in HTLV-I associated myelopathy].
The HTLV-I infection was endemic in south western Kyushu. This human T-lymphotropic virus type I may cause HTLV-I associated myelopathy (HAM), a neurological disease characterized by a spastic paraparesis. And one of the minor diagnostic features of HAM is the presence of cystorectal disturbance. We experienced 35 HAM patients with a neurogenic bladder. A gradually progressive contracted bladder was observed in 3 of them. The main pathological finding in these patients was submucosal infiltration of lymphocytes. These findings suggest that immunologic mechanisms account for the development of bladder lesions.
Nomata
K
K
Department of Urology, Nagasaki University School of Medicine.
Suzu
H
H
Yushita
Y
Y
Kanetake
H
H
Saito
Y
Y
D000368:Aged; D001284:Atrophy; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008875:Middle Aged; D015493:Paraparesis, Tropical Spastic / Q000150:complications*; D001743:Urinary Bladder / Q000473:pathology; D001750:Urinary Bladder, Neurogenic / Q000150:complications* / Q000473:pathology