Origin of so-called mesothelioma of the atrioventricular node. An immunohistochemical study.
To determine the origin of a mesothelioma of the atrioventricular node, immunohistochemical studies that used various antibodies, including the antibody against mesothelial cells, were performed on a mesothelioma of the atrioventricular node in a case. The lining cells of the tubules that composed the tumor were negative when tested with anti-mesothelial cell antibodies. Carcinoembryonic antigen was negative, but the secretory component was positive. Serotonin and calcitonin were positive in a few cells. We concluded that a mesothelial origin was unlikely, and it was suggested that the tumor was of an entodermal origin.
Monma
N
N
Department of Pathology, Iwate Medical University School of Medicine, Morioka, Japan.
Satodate
R
R
Tashiro
A
A
Segawa
I
I
D001283:Atrioventricular Node / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D006338:Heart Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008654:Mesothelioma / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D008875:Middle Aged