title: Presacral extramedullary hematopoiesis in thalassemia intermedia.
abstract: Extramedullary hematopoiesis is manifested by several clinical hematologic disorders including beta-thalassemia major and thalassemia intermedia. We report an unusual case of extramedullary hematopoiesis, which presented as a painful presacral mass in a patient with beta-thalassemia intermedia. The diagnosis was confirmed by a needle biopsy guided by computed tomography. The patient responded well to radiation therapy to the sacral region.
authors.affiliation: Department of Radiology, McMaster University Medical Centre, Hamilton, Ont.
authors.forename: I A
authors.initials: IA
authors.lastname: Sproat
authors.forename: J
authors.initials: J
authors.lastname: Dobranowski
authors.forename: V
authors.initials: V
authors.lastname: Chen
authors.forename: M
authors.initials: M
authors.lastname: Ali
authors.forename: D
authors.initials: D
authors.lastname: Woods
mesh_terms: D000328:Adult; D001707:Biopsy, Needle / Q000379:methods; D005260:Female; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D008297:Male; D008875:Middle Aged; D013131:Spine / Q000000981:diagnostic imaging / Q000502:physiology; D013789:Thalassemia / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D014057:Tomography, X-Ray Computed