title: Cerebral oedema with coning in diabetic keto-acidosis. Report of 2 survivors.
abstract: Two children presented with a first episode of diabetic ketoacidosis. Initially both patients made a good clinical and biochemical recovery, but suddenly developed neurological signs consistent with a diagnosis of tentorial herniation. Cranial computed tomography showed signs of cerebral oedema in both cases with evidence of uncal and tentorial herniation in 1 patient, which resolved after the appropriate treatment. The excellent neurological outcome emphasises the need for early recognition and treatment of sudden onset brain oedema in diabetic keto-acidosis.
authors.affiliation: Department of Paediatrics, University of Stellenbosch.
authors.forename: N N
authors.initials: NN
authors.lastname: Kalis
authors.forename: P L
authors.initials: PL
authors.lastname: van der Merwe
authors.forename: J F
authors.initials: JF
authors.lastname: Schoeman
authors.forename: R M
authors.initials: RM
authors.lastname: Smith
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging; D001929:Brain Edema / Q000000981:diagnostic imaging / Q000209:etiology*; D002648:Child; D016883:Diabetic Ketoacidosis / Q000150:complications*; D005260:Female; D006801:Humans; D014057:Tomography, X-Ray Computed