title: [Effectiveness of long-term treatment with vasodilators in patients with artificial pacemakers].
abstract: The effect of long-term use of venular and arterial vasodilators (molsidomin and nifedipin) on the clinical course and hemodynamic indices was studied in 52 patients with artificial pacemakers. The choice of vasodilator was based on an acute drug test. In the presence of hypertensive disease the calcium antagonist nifedipin was used, in cases of dilatation of the cardiac compartments molsidomin was used. Combination of both drugs was used in patients in whom the acute drug test did not allow to prefer any of the drugs. It is concluded that three-month's treatment resulted in positive changes of the hemodynamics, reduction of the severity of cardiac insufficiency. Side-effects were practically absent.
authors.forename: S
authors.initials: S
authors.lastname: Xalifa
authors.forename: V M
authors.initials: VM
authors.lastname: Berezov
mesh_terms: D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial; D013997:Time Factors; D014665:Vasodilator Agents / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D014665:Vasodilator Agents
vernacular_title: Effectivnost' dlitel'nogo primeneniia vazodilatatorov u bol'nykh s iskusstvennym voditelem ritma.