A multicentric study on sensitivity and specificity of a new in vitro test for measurement of IgE antibodies.
The sensitivity and specificity of the Pharmacia CAP System, a new in vitro assay for measuring IgE antibodies, were evaluated in a multicentric study on 286 allergic patients and 243 normal subjects. Sensitivity was 95.5%, with results significantly better than RAST for some allergens, and specificity was excellent, 98.1%.
Pastorello
E A
EA
1st Department of Internal Medicine, University of Milan, Italy.
Incorvaia
C
C
Pravettoni
V
V
Bonini
S
S
Canonica
G W
GW
Ortolani
C
C
Romagnani
S
S
Tursi
A
A
Zanussi
C
C
D000293:Adolescent; D000328:Adult; D000888:Antibodies, Anti-Idiotypic / Q000032:analysis*; D000918:Antibody Specificity; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis / Q000276:immunology*; D008722:Methods; D008875:Middle Aged; D011852:Radioallergosorbent Test; D012680:Sensitivity and Specificity
D000888:Antibodies, Anti-Idiotypic; C026408:anti-IgE antibodies; D007073:Immunoglobulin E