Nasal provocation test with lysine acetylsalicylate in aspirin-sensitive patients.
The authors have studied nasal provocation testing (NPT) with aspirin in 45 aspirin-sensitive patients (40 affected by nasal polyposis) and in 38 aspirin-tolerant patients (27 affected by nasal polyposis). The test was positive in 37.7% of aspirin-intolerant subjects, but only in 7.9% of subjects in the control group (P less than .01).
Patriarca
G
G
Catholic University of Rome, Italy.
Nucera
E
E
DiRienzo
V
V
Schiavino
D
D
Pellegrino
S
S
Fais
G
G
D000328:Adult; D000368:Aged; D000700:Analgesics / Q000009:adverse effects*; D001241:Aspirin / Q000009:adverse effects* / Q000031:analogs & derivatives*; D004342:Drug Hypersensitivity / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D008239:Lysine / Q000009:adverse effects / Q000031:analogs & derivatives*; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000473:pathology; D009299:Nasal Provocation Tests
D000700:Analgesics; D008239:Lysine; D001241:Aspirin; C010395:acetylsalicylic acid lysinate