[DNA from human lymphocytes contains a sequence, homologous to immunoglobulin gene kappa].
DNA released by human lymphocytes and hyman blood plasma DNA were examined by the electrophoresis, electron microscopy and Southern blot hybridization. The data obtained suggested that DNA released by lymphocytes contains covalently closed circular molecules. By the technique of the Southern blot analysis it was shown that DNA released by lymphocytes and human blood plasma DNA contain discretely sized molecules homologous to the C kappa fragment of the human Ig gene.
Vasiukhin
V I
VI
Lipskaia
L A
LA
Tsvetkov
A G
AG
Podgornaia
O I
OI
D001345:Autoradiography; D015139:Blotting, Southern; D004247:DNA / Q000235:genetics* / Q000302:isolation & purification / Q000648:ultrastructure; D004587:Electrophoresis, Agar Gel; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000235:genetics*; D008214:Lymphocytes / Q000378:metabolism*; D008854:Microscopy, Electron; D015183:Restriction Mapping; D012689:Sequence Homology, Nucleic Acid
D007145:Immunoglobulin kappa-Chains; D004247:DNA
DNK, vykhodiashchaia iz limfotsitov cheloveka, soderzhit posledovatel'nosti, gomologichnye immunoglobulinovomu genu kappa.