Perinatal transmission of Chlamydia trachomatis. The use of serological tests in detecting infected women.
A study is presented on the use of serological tests for the detection of Chlamydia trachomatis in 273 pregnant women. 166 were cultured for C. trachomatis and nine (5.4%) were positive. Three culture-positive babies, all born to culture-positive women, had conjunctivitis. Elevated IgG and IgA antibody levels were seen in six (67%) and three (33%) of the infected women, respectively. Three (2.4%) of IgG antibody-negative mothers (n = 126) were positive by culture. Compared to serology culture of the microorganism appears as the most reliable way of detecting infected women.
Dannevig
L
L
Dept. of Opthalmology, University Hospital, Norway.
Schive
B
B
Straume
B K
BK
Melby
K
K
D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis; D002690:Chlamydia Infections / Q000175:diagnosis / Q000635:transmission*; D002692:Chlamydia trachomatis / Q000276:immunology; D003235:Conjunctivitis, Inclusion / Q000635:transmission*; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007231:Infant, Newborn; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis; D011933:Reagent Kits, Diagnostic
D000907:Antibodies, Bacterial; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D011933:Reagent Kits, Diagnostic