Solid versus liquid lithium--a pharmacokinetic study.
The pharmacokinetics of solid lithium (Priadel) were compared with liquid lithium citrate in nine manic depressive patients. The results show that whilst the 12-h steady-state levels are similar, there are significant differences in the degree and rate of absorption between the two preparations. The clinical implications of this are discussed further.
Markar
H R
HR
Department of Psychiatry, Addenbrooke's Hospital, University of Cambridge, U.K.
Ascough
G
G
D000328:Adult; D001682:Biological Availability; D002951:Citrates; D003866:Depressive Disorder / Q000097:blood* / Q000188:drug therapy; D006801:Humans; D008094:Lithium / Q000493:pharmacokinetics*; D016651:Lithium Carbonate
D002951:Citrates; D016651:Lithium Carbonate; C070669:lithium citrate; D008094:Lithium