title: [30-months extracorporeal electrohydraulic shock-wave lithotripsy of gallstones using the MPL-9000 at the Zurich University Hospital].
abstract: The effect of extracoporeal shockwave lithotripsy (ESWL) in combination with oral chemolitholysis on gallstone clearance was tested in a prospective study. We used a non-waterbath lithotripter, and the patients were treated without general anesthesia or intravenous analgesia. They solely received oral or subcutaneous premedication. Within the 30 months study-period 78 patients were selected according to the "Munich-criteriae". At the end of the study period 33 patients were free of stones, 20 patients had residual fragments, and 25 patients stopped the therapy prior to complete stone clearance because of compliance (n = 11), or methodological (n = 14) problems. This includes 3 patients in whom the ESWL had to be discontinued because of pain. No severe complications were seen with the exception of one attack of acute pancreatitis, from which the patient recovered. The rate of stone clearance was analyzed using the life-table calculation according to KAPLAN-MEIER to weigh the follow-up time of each patient. At 12 months it revealed a stonefree rate of 70% in patients who did not discontinue the treatment because of methodological problems. The advantage of ESWL is the possibility to treat gallstones without general anesthesia or intravenous analgesia. However, the patient-population must be highly selected, and there is the risk of recurrence.
authors.affiliation: Klinik für Viszeralchirurgie (Departement Chirurgie), Universitätsspital Zürich.
authors.forename: T
authors.initials: T
authors.lastname: Frick
authors.forename: R
authors.initials: R
authors.lastname: Hoffmann
authors.forename: F
authors.initials: F
authors.lastname: Largiadèr
authors.forename: R
authors.initials: R
authors.lastname: Ammann
authors.forename: W
authors.initials: W
authors.lastname: Häcki
authors.forename: W
authors.initials: W
authors.lastname: Fuchs
mesh_terms: D000328:Adult; D002769:Cholelithiasis / Q000628:therapy*; D004987:Ethers / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008096:Lithotripsy / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D008297:Male; D008738:Methyl Ethers; D008875:Middle Aged; D011446:Prospective Studies; D012997:Solvents / Q000627:therapeutic use*
chemical_list: D004987:Ethers; D008738:Methyl Ethers; D012997:Solvents; C043243:methyl tert-butyl ether
vernacular_title: 30 Monate extrakorporale elektrohydraulische Stosswellenlithotripsie von Gallensteinen mit dem MPL-9000 am Universitätsspital Zürich.