title: [The use of antioxidants in the complex therapy of patients with infiltrating pulmonary tuberculosis].
abstract: Clinical and laboratory investigations examined the possibility of a lower load of antibacterial drugs (ABD) in combination with the two antioxidants, alpha-tocopherol and sodium thiosulfate, in combined therapy of patients with infiltrative pulmonary tuberculosis. Higher efficacy of two ABDs supplemented by two antioxidants than three or more ABDs was evidenced by a shorter period of sputum negativity (1.6 +/- 0.26 and 2.7 +/- 0.27 months; p less than 0.01) and higher rates of cavity closure (95.6 +/- 4.3 and 63.2 +/- 6.7%; p less than 0.05).
authors.forename: E V
authors.initials: EV
authors.lastname: Starostenko
authors.forename: B M
authors.initials: BM
authors.lastname: Dolzhanskiĭ
authors.forename: A M
authors.initials: AM
authors.lastname: Salpagarov
authors.forename: T N
authors.initials: TN
authors.lastname: Levchenko
mesh_terms: D000975:Antioxidants / Q000627:therapeutic use*; D006801:Humans; D008854:Microscopy, Electron; D009169:Mycobacterium tuberculosis / Q000187:drug effects / Q000648:ultrastructure; D013183:Sputum / Q000382:microbiology; D013885:Thiosulfates / Q000627:therapeutic use*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy* / Q000382:microbiology; D014810:Vitamin E / Q000627:therapeutic use*
chemical_list: D000975:Antioxidants; D013885:Thiosulfates; D014810:Vitamin E; C017717:sodium thiosulfate
vernacular_title: Primenenie antioksidantov v kompleksnom lechenii bol'nykh infil'trativnym tuberkulezom legkikh.