title: Low frequency hearing threshold determination in newborns, infants and mentally retarded children by middle latency responses.
abstract: Middle latency (10-50 ms) responses (MLR) evoked by tone-pips (1,000 Hz 500 Hz) and early (0-10 ms) auditory evoked potentials (EAEP) evoked by chicks were recorded on 68 newborn babies (premature or at term), infants and children, some with central nervous system or psychiatric disorders, who had normal or impaired hearing. MLR were obtained either during sleep, chloral-hydrate sedation or ketamine anesthesia. Thresholds estimated from MLR and EAEP were compared to those from subsequent psychoacoustic pure tone testing. We confirm that MLR provide good threshold estimates for hearing in the low frequency range, whereas click evoked EAEP are good threshold indicators only for high frequencies.
authors.affiliation: Department of Otolaryngology, Cantonal University Hospital, Geneva, Switzerland.
authors.forename: R
authors.initials: R
authors.lastname: Hausler
authors.forename: M
authors.initials: M
authors.lastname: Cao
authors.forename: C
authors.initials: C
authors.lastname: Magnin
authors.forename: P
authors.initials: P
authors.lastname: Mulette
mesh_terms: D000161:Acoustic Stimulation; D001300:Audiometry, Evoked Response / Q000379:methods*; D001301:Audiometry, Pure-Tone; D001309:Auditory Threshold / Q000187:drug effects; D001927:Brain Diseases / Q000150:complications / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D002697:Chloral Hydrate / Q000494:pharmacology; D005072:Evoked Potentials, Auditory / Q000187:drug effects; D006311:Hearing Disorders / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn / Q000502:physiology*; D008607:Intellectual Disability / Q000150:complications / Q000503:physiopathology*; D007649:Ketamine / Q000494:pharmacology; D001523:Mental Disorders / Q000150:complications / Q000503:physiopathology; D011930:Reaction Time / Q000187:drug effects; D012189:Retrospective Studies
chemical_list: D002697:Chloral Hydrate; D007649:Ketamine