title: Crossover phenomena in epileptic syndromes of childhood.
abstract: Benign Rolandic epilepsy (BRE) and primary generalized epilepsy (PGE) are found at about the same period of childhood. Crossover from PGE to BRE and vice versa may occur; two short case reports provide further evidence for this development. Hence, transitions from a primarily generalized to a focal (partial) epileptic seizure disorder and vice versa is a possibility. Both PGE and BRE are based upon states of hyperexcitability, i.e. dysfunctional rather than structural abnormalities that are capable of changing their spatial distribution.
authors.affiliation: Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland.
authors.forename: A N
authors.initials: AN
authors.lastname: de Melo
authors.forename: E
authors.initials: E
authors.lastname: Niedermeyer
mesh_terms: D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004827:Epilepsy / Q000503:physiopathology*; D004832:Epilepsy, Absence / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D003294:Seizures, Febrile / Q000503:physiopathology