title: Surgical complications of Chagas' disease: megaesophagus, achalasia of the pylorus, and cholelithiasis.
abstract: Three surgical complications of Chagas' disease--megaesophagus, achalasia of the pylorus, and cholelithiasis--were evaluated within the framework of the experience acquired in the management of 840 cases of megaesophagus--722 in the nonadvanced stage of the disease and 118 with advanced disease (dolichomegaesophagus). In the group of the 722 patients with nonadvanced disease, achalasia of the pylorus was present in 140 (19.4%), and in the total of 840 patients, uncomplicated cholelithiasis without chagasic involvement of the gallbladder and/or papilla was observed in 58 (6.9%). The 722 subjects with nonadvanced megaesophagus were submitted to wide esophagocardiomyectomy performed at the level of the anterior esophagogastric junction, combined with an antireflux valvuloplasty procedure. We recorded no mortality, and 95% excellent and good results in long-term follow-up. On the other hand, dolichomegaesophagus required esophageal resection with reconstruction by means of an esophagogastroplasty placed in the esophageal bed. The mortality rate was 4.2% (5/118); the main postoperative complications were pleural effusion (22%) and fistulas of the esophagogastric anastomosis (8.4%). Postoperatively, the patients adapted well to their new anatomy and gained weight. Achalasia of the pylorus was confirmed by delayed gastric emptying time. This entity was managed by concomitant antropyloromyectomy without mortality. Cholelithiasis was managed by cholecystectomy and radiologic exploration of the bile ducts.
authors.affiliation: Department of Gastroenterology, Hospital das Clínicas, University of São Paulo Medical School, Brazil.
authors.forename: H W
authors.initials: HW
authors.lastname: Pinotti
authors.forename: V N
authors.initials: VN
authors.lastname: Felix
authors.forename: B
authors.initials: B
authors.lastname: Zilberstein
authors.forename: I
authors.initials: I
authors.lastname: Cecconello
mesh_terms: D014355:Chagas Disease / Q000150:complications*; D002769:Cholelithiasis / Q000209:etiology / Q000601:surgery*; D004931:Esophageal Achalasia / Q000209:etiology / Q000601:surgery*; D006801:Humans; D011183:Postoperative Complications; D011707:Pyloric Stenosis / Q000209:etiology / Q000601:surgery*