In vitro evaluation of drug-induced toxic effects on the immune system as assessed by proliferative assays and cytokine production.
Pallardy
M
M
Laboratoire de Toxicologie, Faculté de Pharmacie Paris XI, Chatenay-Malabry, France.
Lebrec
H
H
Blot
C
C
Burleson
G R
GR
Bohuon
C
C
D000658:Amoxicillin / Q000494:pharmacology; D000818:Animals; D001711:Biotransformation; D002455:Cell Division / Q000187:drug effects; D002927:Cimetidine / Q000494:pharmacology; D016207:Cytokines / Q000096:biosynthesis*; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D005665:Furosemide / Q000494:pharmacology; D015870:Gene Expression / Q000187:drug effects; D007107:Immune System / Q000187:drug effects*; D007166:Immunosuppressive Agents / Q000494:pharmacology; D007213:Indomethacin / Q000494:pharmacology; D007376:Interleukin-2 / Q000494:pharmacology; D008213:Lymphocyte Activation / Q000187:drug effects; D051379:Mice; D008934:Mitogens / Q000494:pharmacology; D011342:Procainamide / Q000494:pharmacology; D013601:T-Lymphocytes / Q000187:drug effects; D014116:Toxicology / Q000379:methods*
D016207:Cytokines; D007166:Immunosuppressive Agents; D007376:Interleukin-2; D008934:Mitogens; D005665:Furosemide; D002927:Cimetidine; D000658:Amoxicillin; D011342:Procainamide; D007213:Indomethacin