Antithrombin III activity in horses with colic: an analysis of 46 cases.
Antithrombin-III (AT-III) activity was measured at the time of admission in 46 horses referred with colic. Differences in AT-III activities between animals treated medically or surgically and survivors or non-survivors were compared. The mean AT-III values for the horses treated medically (76.2 per cent), surgical survivors (69.5 per cent) and surgical non-survivors (55.9 per cent) were significantly different from the reference value for healthy adults (92 to 108 per cent). The mean AT-III activity of the survivors was significantly (P less than 0.01) greater than that of the nonsurvivors. The majority of the survivors (11 to 13 horses) had AT-III activities exceeding 60 per cent of normal, whereas that of 10 of the 14 non-survivors was less than 60 per cent of normal. There was an apparent distinction between the survivors and non-survivors at approximately 60 per cent of normal AT-III activity.
Darien
B J
BJ
Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing 48824.
Potempa
J
J
Moore
J N
JN
Travis
J
J
D000818:Animals; D000990:Antithrombin III / Q000032:analysis*; D003085:Colic / Q000097:blood / Q000601:surgery / Q000628:therapy / Q000662:veterinary*; D006734:Horse Diseases / Q000097:blood* / Q000601:surgery / Q000628:therapy; D006736:Horses; D011379:Prognosis
D000990:Antithrombin III