title: Comparison of yearling, two-year-old and adult Thoroughbreds using a standardised exercise test.
abstract: The purpose of this study was to compare exercise measurements in yearling, two-year-old and adult Thoroughbreds using a standardised treadmill incremental exercise test. Peak oxygen consumption (VO2 peak: 128.0 +/- 2.1, 140.0 +/- 2.1, 163.7 +/- 3.4; ml/kg/min +/- se, P less than 0.05), peak packed cell volume (PCV peak: 0.50 +/- 0.01, 0.58 +/- 0.01, 0.64 +/- 0.01 litres/litre +/- se, P less than 0.05) and the maximum number of steps completed in the exercise test (STEPmax: 7.7 +/- 0.1, 8.1 +/- 0.1, 8.6 +/- 0.1; steps +/- se, P less than 0.05) increased with age and degree of physical activity. Peak venous lactate concentration (LACpeak: 21.3 +/- 1.5, 19.5 +/- 1.7, 14.4 +/- 1.7; mmol/litre +/- se, P less than 0.05) and peak respiratory exchange ratio (Rpeak) were significantly higher in both groups of younger horses compared to the adult racehorses. Peak heart rate (HRpeak: 230 +/- 2, 231 +/- 3, 229 +/- 3; beats/min +/- se) did not change with age or training. The rate of change of VO2 between steps in the exercise test (VO2trans) was significantly lower in the adult racehorses at the highest exercise intensities. The slopes of the linear approximation between R (LinR bx), the natural log transformation of venous lactate concentration (LogLAC bx), and heart rate (HR bx) with velocity were significantly lower in the trained adult racehorses. The slope of venous lactate concentration normalised to per cent VO2peak (LogLAC per cent bx) was significantly lower and R breakpoint (R brkpt) normalised to per cent VO2peak was significantly higher in the trained adult racehorses. There was a more rapid decrease in venous lactate and a more rapid return to initial R values in the adult horses relative to the younger, untrained horses. No significant age or training effects were found in the remainder of the post exercise measurements. These results indicate that aerobic power and exercise capacity increased with age and training. Anaerobic power was already well developed even at a young age.
authors.affiliation: Tufts University School of Veterinary Medicine, North Grafton, Massachusetts 01536.
authors.forename: H J
authors.initials: HJ
authors.lastname: Seeherman
authors.forename: E A
authors.initials: EA
authors.lastname: Morris
mesh_terms: D000367:Age Factors; D000818:Animals; D001798:Blood Proteins / Q000032:analysis; D002245:Carbon Dioxide / Q000378:metabolism; D005080:Exercise Test / Q000662:veterinary; D005260:Female; D005684:Gait / Q000502:physiology; D006339:Heart Rate; D006400:Hematocrit / Q000662:veterinary; D006736:Horses / Q000502:physiology*; D007773:Lactates / Q000097:blood; D008297:Male; D010100:Oxygen / Q000378:metabolism; D010101:Oxygen Consumption; D010805:Physical Conditioning, Animal
chemical_list: D001798:Blood Proteins; D007773:Lactates; D002245:Carbon Dioxide; D010100:Oxygen