Lack of specific saxitoxin binding to rat mast cells.
We studied whether or not mast cells are endowed with specific sodium channels, by using tritiated saxitoxin which binds to site 1 of sodium channels on excitable tissues. Our results suggest that rat pleural and peritoneal mast cells lack specific sodium channels.
Vieytes
M R
MR
Departmentos de Farmacología y Fisiología, Facultad de Veterinaria, Universidad de Santiago de Compostela, Lugo, Spain.
Louzao
M C
MC
Bujan
M J
MJ
Alfonso
A
A
Cabado
A
A
de la Cruz
L F
LF
Botana
L M
LM
D000818:Animals; D008407:Mast Cells / Q000378:metabolism*; D010529:Peritoneal Cavity / Q000166:cytology; D010994:Pleura / Q000166:cytology; D051381:Rats; D012530:Saxitoxin / Q000378:metabolism*
D012530:Saxitoxin