Solvent abuse, toluene acidosis and diabetic ketoacidosis.
Solvent abuse in adolescents and young adults has been reported to cause a metabolic acidosis with a normal or increased anion gap (Streicher et al., 1981; Voights & Kaufman, 1983, Anonymous, 1988). We report a particularly severe clinical problem produced by the combination of toluene intoxication and diabetic ketoacidosis.
Brown
J H
JH
Sir George E. Clark Metabolic Unit, Victoria Hospital, Belfast, Northern Ireland.
Hadden
D R
DR
Hadden
D S
DS
D000096:Acetone / Q000097:blood; D000136:Acid-Base Equilibrium / Q000187:drug effects; D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D016883:Diabetic Ketoacidosis / Q000139:chemically induced* / Q000150:complications / Q000378:metabolism; D005260:Female; D006801:Humans; D012997:Solvents / Q000506:poisoning*; D019966:Substance-Related Disorders; D014050:Toluene / Q000097:blood / Q000506:poisoning*
D012997:Solvents; D000096:Acetone; D014050:Toluene