Trisomy 13q in a case of acute leukemia with lineage inconsistency.
A case of acute leukemia has two distinct immature blast lines, lineage inconsistency with CD 4 positivity, and trisomy 13q as the effective cytogenetic abnormality. This case represents another instance of trisomy 13 with acute leukemia developing in a more primitive pluripotent stem cell.
Comenzo
R
R
Department of Medicine, New England Medical Center Hospital, Boston, MA 02111.
Roth
D
D
Desforges
J F
JF
Berkman
E M
EM
D015703:Antigens, CD / Q000032:analysis; D001853:Bone Marrow / Q000473:pathology; D002871:Chromosome Banding; D002882:Chromosomes, Human, Pair 13; D006801:Humans; D016130:Immunophenotyping; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000276:immunology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D014314:Trisomy
D015703:Antigens, CD