title: [Histologic signs of cutaneous aging].
abstract: The changes induced by ageing of the skin are particularly visible in photo-exposed areas, indicating the interaction between actinic factors and factors specific to the ageing process itself. The corresponding histological signs affect various structures: epidermis (thinning of the epidermis, reduced cell proliferation...), dermis-epidermis junction (disappearance of the microvilli with defective adhesion of the epidermis to the dermis), dermis (degeneration of elastin and collagen, which is photoinduced, and a moth-eaten appearance with loss of microfibrils as a result of time-related ageing), microcirculation (reduced vascularization, particularly visible in photo-exposed areas...) appendages.
authors.affiliation: Service de Dermatologie, CHU Timone, Marseille.
authors.forename: C
authors.initials: C
authors.lastname: Mestre-Deharo
authors.forename: J
authors.initials: J
authors.lastname: Sayag
mesh_terms: D004817:Epidermis / Q000473:pathology / Q000502:physiology / Q000648:ultrastructure; D006197:Hair / Q000473:pathology / Q000502:physiology; D006801:Humans; D015603:Keratinocytes / Q000473:pathology / Q000502:physiology / Q000648:ultrastructure; D007801:Langerhans Cells / Q000473:pathology / Q000502:physiology / Q000648:ultrastructure; D008544:Melanocytes / Q000473:pathology / Q000502:physiology / Q000648:ultrastructure; D009262:Nails / Q000473:pathology / Q000502:physiology; D012627:Sebaceous Glands / Q000473:pathology / Q000502:physiology; D015595:Skin Aging / Q000502:physiology*; D013545:Sweat Glands / Q000033:anatomy & histology / Q000473:pathology
vernacular_title: Signes histologiques du vieillissement cutané.