Postmortem changes in hapten-specific IgE antibody responses in mice.
This Study was carried out to examine the post-mortem stability of hapten-specific immunoglobulin E (IgE) antibody in mice by the passive cutaneous anaphylaxis test in rats. In vitro IgE antibody responses in blood were stable for 3 days at room temperature. Even in cases when blood could not be obtained from the cadaver it was possible to measure the hapten-specific IgE antibody response up to 3 days after death using the supernatant of the visceral homogenates.
Hieda
Y
Y
Department of Legal Medicine, Fukuoka University School of Medicine, Japan.
Kageura
M
M
Hara
K
K
Kashimura
S
S
D000818:Animals; D000888:Antibodies, Anti-Idiotypic / Q000032:analysis*; D005260:Female; D006433:Hemocyanins / Q000276:immunology*; D007073:Immunoglobulin E / Q000276:immunology*; D008297:Male; D051379:Mice; D011180:Postmortem Changes; D051381:Rats; D011919:Rats, Inbred Strains
C042158:2,4-dinitrophenyl keyhole limpet hemocyanin; D000888:Antibodies, Anti-Idiotypic; D007073:Immunoglobulin E; D006433:Hemocyanins