Adherence of Streptococcus suis capsular type 2 to porcine lung sections.
The present study was undertaken to evaluate the ability of 33 Streptococcus suis capsular type 2 isolates to adhere to frozen sections of porcine lung. Twenty isolates originated from diseased pigs and 13 from the nasal cavities of clinically healthy pigs. All isolates from diseased animals adhered to lung sections; isolates from pneumonia adhered, in general, in greater numbers than isolates from meningitis. Only four isolates from clinically healthy animals showed a weak adherence to lung sections. Hydrophobic surface properties were also evaluated. All isolates tested appeared to possess a hydrophilic cell surface. The thickness of the capsular material correlated well with the degree of adherence. However, when the adherence capacity of a noncapsulated mutant was compared with that of the parent strain, it was found that the mutant strain had at least the same adherence capacity as the capsulated parent strain. The data suggest that S. suis capsular type 2 isolates involved in pathological conditions can adhere to porcine lung tissue. The adherence activity does not seem to involve hydrophobic interactions. The amount of capsular material seems to influence the adherence activity, but is probably not the only mechanism involved.
Gottschalk
M
M
Groupe de Recherche sur les Maladies Infectieuses du Porc. Faculté de médecine vétérinaire, Université de Montréal, Québec.
Petitbois
S
S
Higgins
R
R
Jacques
M
M
D000818:Animals; D001422:Bacterial Adhesion; D005629:Frozen Sections; D008168:Lung / Q000382:microbiology*; D008581:Meningitis / Q000382:microbiology / Q000662:veterinary; D008854:Microscopy, Electron; D009154:Mutation; D009296:Nasal Cavity / Q000382:microbiology; D011014:Pneumonia / Q000382:microbiology / Q000662:veterinary; D013290:Streptococcal Infections / Q000382:microbiology / Q000662:veterinary*; D013291:Streptococcus / Q000235:genetics / Q000378:metabolism* / Q000648:ultrastructure; D013499:Surface Properties; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology*