[Lymphocyte subpopulations in rheumatoid arthritis patients, their relatives and spouses].
A study of lymphocytic sub-populations of patients with rheumatoid arthritis, their families and partners, is presented. The determination was carried out by means of monoclonal antibodies, analysing: T cells sub-population (CD3, CD4, CD8 and quotient CD4/CD8); B cells sub-population (B1); activated cells (OK1a); monocytes and NK cells (OKM1 and BMA 070). The results showed an increase of CD3 sub-population (T total lymphocytes) in patients with RA and their families. The meaning of these results is difficult to evaluate as lymphocyte sub-population is affected by several variables. The lack of modification of suppressor population, CD4/CD8 quotient and IKM1 cells in RA patients is probably due to the moderate activity of the disease.
Rodríguez Pérez
M
M
Cátedra de Reumatología, Servicio de Reumatología, Hospital Clínico Universitario, Facultatd de Medicina Granada.
Mataran Pérez
L
L
González Dominguez
J
J
Gutiérrez Gea
F
F
Abellán Pérez
M
M
González Utrilla
A
A
Salvatierra Ríos
D
D
D000911:Antibodies, Monoclonal; D001172:Arthritis, Rheumatoid / Q000276:immunology*; D001327:Autoimmune Diseases / Q000276:immunology*; D003601:Cytotoxicity Tests, Immunologic / Q000379:methods; D005192:Family Health; D005260:Female; D006801:Humans; D016131:Lymphocyte Subsets / Q000276:immunology*; D008297:Male; D008875:Middle Aged
D000911:Antibodies, Monoclonal
Subpoblaciones linfocitarias en pacientes con artritis reumatoide, sus familiares y cónyuges.