Inverse relationship between risk of SIDS and early neonatal mortality: study of state mortality rates.
It was predicted that at the state level early neonatal (0-6 days) mortality rates and rates for sudden infant death syndrome (SIDS) in the age range 7-364 days would be negatively correlated. Using published data for each of the 50 states and the District of Columbia over the 5-year period 1980-1984, the actual correlation was -0.68 (p less than 0.001). In a breakdown of early neonatal mortality by age at death, rates for infants aged less than 1 hour proved to be the exception; their rates were not found to be negatively correlated with the rates for SIDS (r = +0.20). This finding probably reflects uniformity in the quality of obstetric care. The geographic variation in mortality rates for infants aged 1 hour to 6 days might be explained by variation in the probability of a mother and fetus sharing one or more HLA antigens.
Spiers
P S
PS
Department of Pediatrics, University of Washington, Seattle 98195.
D002423:Cause of Death; D015986:Confounding Factors, Epidemiologic; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D015994:Incidence; D007223:Infant; D007226:Infant Mortality; D007231:Infant, Newborn; D008957:Models, Genetic; D015233:Models, Statistical; D011237:Predictive Value of Tests; D012111:Residence Characteristics; D012307:Risk Factors; D013398:Sudden Infant Death / Q000453:epidemiology* / Q000209:etiology; D014481:United States / Q000453:epidemiology; D044465:White People / Q000235:genetics
D006680:HLA Antigens