title: Signal averaging of the electrocardiogram in the remote differential diagnosis of broad complex tachycardias.
abstract: The diagnosis of the origin of a broad complex tachycardia may be difficult, especially in the absence of a 12-lead electrocardiogram of the tachycardia. This study investigates the value of signal averaging in the differential diagnosis of broad complex tachycardia. Signal averaging during sinus rhythm was performed in 102 consecutive patients who presented with broad complex tachycardia (QRS width greater than 110 ms), in whom a definitive electrophysiological diagnosis was made. The presence of late potentials was determined on the basis of two definitions, the second including total QRS duration. The patients studied included 75 with ventricular tachycardia; 33 of these patients had suffered previous myocardial infarction, five had dilated cardiomyopathy, and 37 had a 'normal' heart. Of the 27 patients with supraventricular tachycardia, 22 had an atrioventricular accessory pathway (seven with a delta wave in sinus rhythm), three had atrioventricular nodal tachycardia and two had atrial tachycardia. The sensitivity of late potentials for the diagnosis of ventricular tachycardia was low utilizing both definitions (28% and 45%) although specificity was high (96% and 95%). The sensitivity for the diagnosis of ventricular tachycardia was higher for patients with ischaemic heart disease (43% and 70%) but very low for patients with ventricular tachycardia and a normal heart (16% and 22%). In conclusion, signal averaging in the remote diagnosis of broad complex tachycardia is specific but not sensitive for ventricular tachycardia, which limits its usefulness in selecting patients for electrophysiological study.
authors.affiliation: Department of Cardiological Sciences, St. George's Hospital Medical School, London, U.K.
authors.forename: M J
authors.initials: MJ
authors.lastname: Griffith
authors.forename: M A
authors.initials: MA
authors.lastname: de Belder
authors.forename: D
authors.initials: D
authors.lastname: Mehta
authors.forename: D E
authors.initials: DE
authors.lastname: Ward
authors.forename: A J
authors.initials: AJ
authors.lastname: Camm
mesh_terms: D003327:Coronary Disease / Q000150:complications; D003937:Diagnosis, Differential; D004562:Electrocardiography; D006352:Heart Ventricles; D006801:Humans; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D013610:Tachycardia / Q000175:diagnosis*; D013617:Tachycardia, Supraventricular / Q000175:diagnosis