title: Whole blood electrolyte assay using ChemPro 500. A comparison of assay performance with standard laboratory instruments.
abstract: The ChemPro 500 'near-the-patient' analyser, with ChemPro 'Ion Profile' sensor cards, was evaluated for the assay of pH, Ca2+, K+ and Na+ in whole blood samples from patients in the intensive care unit or during surgery for heart or major blood vessel disease, or for liver transplantation. Imprecisions estimated from replicate whole blood measurements were much greater for all four ions than even the least stringent of the generally accepted analytical goals, and much greater than those estimated using quality assurance materials. Comparisons of assayed values with those obtained using standard laboratory instruments showed significant constant and proportional biases. The performance of the ChemPro 500 with the Ion Profile cards gave us no confidence in recommending their use to anaesthetists and intensivists.
authors.affiliation: City General Hospital, Stoke on Trent.
authors.forename: J M
authors.initials: JM
authors.lastname: Thompson
authors.forename: C
authors.initials: C
authors.lastname: Emmett
authors.forename: S C
authors.initials: SC
authors.lastname: Smith
authors.forename: R
authors.initials: R
authors.lastname: Cramb
authors.forename: P
authors.initials: P
authors.lastname: Hutton
mesh_terms: D015374:Biosensing Techniques / Q000592:standards*; D001774:Blood Chemical Analysis / Q000295:instrumentation*; D002118:Calcium / Q000097:blood; D006801:Humans; D006863:Hydrogen-Ion Concentration; D011188:Potassium / Q000097:blood; D011786:Quality Control; D012964:Sodium / Q000097:blood
chemical_list: D012964:Sodium; D011188:Potassium; D002118:Calcium