title: Understanding tolerance, physical dependence and addiction in the use of opioid analgesics.
authors.forename: R E
authors.initials: RE
authors.lastname: Enck
mesh_terms: D004361:Drug Tolerance / Q000502:physiology*; D006801:Humans; D009294:Narcotics / Q000009:adverse effects*; D009369:Neoplasms / Q000503:physiopathology*; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D013375:Substance Withdrawal Syndrome / Q000503:physiopathology; D019966:Substance-Related Disorders / Q000453:epidemiology / Q000503:physiopathology*
chemical_list: D009294:Narcotics