Gi-2 is at the centre of an active phosphorylation/dephosphorylation cycle in hepatocytes: the fine-tuning of stimulatory and inhibitory inputs into adenylate cyclase in normal and diabetic states.
Houslay
M D
MD
Department of Biochemistry, University of Glasgow, U.K.
D000262:Adenylyl Cyclases / Q000378:metabolism*; D000818:Animals; D003920:Diabetes Mellitus / Q000201:enzymology*; D019204:GTP-Binding Proteins / Q000378:metabolism*; D005934:Glucagon / Q000378:metabolism; D008099:Liver / Q000166:cytology / Q000201:enzymology*; D010766:Phosphorylation; D011493:Protein Kinase C / Q000378:metabolism; D015398:Signal Transduction
D005934:Glucagon; D011493:Protein Kinase C; D019204:GTP-Binding Proteins; D000262:Adenylyl Cyclases