title: Gadopentetate dimeglumine-enhanced MR imaging of the musculoskeletal system.
abstract: Contrast-enhanced MR imaging with gadopentetate dimeglumine has been used in the evaluation of musculoskeletal disorders only in recent years, and for the most part it is still under investigation. Review of the literature identified potential uses for this technique: (1) in the spine, for differentiation between scar tissue and recurrent disk herniation and for evaluation of epidural tumors; (2) in musculoskeletal tumors, for differentiation between tumor necrosis and peritumoral edema and for characterization and evaluation of tumors before and after treatment; (3) in the joints for delineation of cartilage and tendon tears, with intraarticular injection, and for differentiation between pannus and joint effusion, with IV injection; and (4) for delineation of infectious processes. Further studies are needed to confirm most of these potential indications. It is unlikely that gadopentetate dimeglumine-enhanced MR imaging will become a routine part of musculoskeletal MR imaging, and its use will be reserved for specific circumstances.
authors.affiliation: Department of Radiology, Ohio State University Hospitals, Columbus 43210.
authors.forename: J
authors.initials: J
authors.lastname: Beltran
authors.forename: V
authors.initials: V
authors.lastname: Chandnani
authors.forename: R A
authors.initials: RA
authors.lastname: McGhee
authors.forename: S
authors.initials: S
authors.lastname: Kursunoglu-Brahme
mesh_terms: D001847:Bone Diseases / Q000175:diagnosis*; D003287:Contrast Media; D004338:Drug Combinations; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D007592:Joint Diseases / Q000175:diagnosis; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008536:Meglumine; D009135:Muscular Diseases / Q000175:diagnosis*; D009942:Organometallic Compounds; D004369:Pentetic Acid; D012983:Soft Tissue Neoplasms / Q000175:diagnosis; D013122:Spinal Diseases / Q000175:diagnosis
chemical_list: D003287:Contrast Media; D004338:Drug Combinations; D009942:Organometallic Compounds; D008536:Meglumine; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA