[Effects of excess and deficiency of thyroid hormones in the body upon blood melatonin in pubertal male rats].
Experiments have been carried out on Wistar line pubertal male rats in Winter. Radioimmunological method showed, that in intact animals the night peak of melatonin in blood was 994,36 +/- 195,99 pM/l, following ten-days intramuscular thyroxin injection (100 mg/100 g body mass)--2560,52 +/- 322,04 pM/1 and 20 days after, following bilateral thyroidectomy--117,13 +/- 16,35 pM/l, that totals 257,5% and 11,8%, respectively. Thus, the night peak of melatonin depends upon thyroid hormones concentration in blood.
Bondarenko
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D000818:Animals; D008297:Male; D008550:Melatonin / Q000097:blood*; D010870:Pineal Gland / Q000502:physiology; D011863:Radioimmunoassay; D051381:Rats; D011919:Rats, Inbred Strains; D013961:Thyroid Gland / Q000502:physiology; D013963:Thyroid Hormones / Q000097:blood*; D013965:Thyroidectomy; D013974:Thyroxine / Q000008:administration & dosage / Q000494:pharmacology; D013997:Time Factors
D013963:Thyroid Hormones; D008550:Melatonin; D013974:Thyroxine
Vliianie izbytka i nedostatka tireoidnykh gormonov v organizme na kontsentratsiiu melatonina v krovi u polovozrelykh krys-samtsov.