title: Differentiation between hemangiomas and metastases of the liver with ultrafast MR imaging: preliminary results with T2 calculations.
abstract: We studied the efficacy of T2 measurements at high field strength in distinguishing between liver hemangiomas and hepatic metastases when an ultrafast (single-excitation) MR imaging technique is used. Fourteen patients with known liver tumors were imaged in a 2.0-T prototype ultrafast MR scanner with a spin-echo (infinite TR and TE of 30-340 msec) pulse sequence. Each image was obtained with a total data acquisition time of 20 msec. T2 calculations for hepatic metastases (n = 6) showed a mean of 79.3 +/- 13.5 msec, whereas hemangiomas (n = 8) showed a T2 of 139.8 +/- 18.8 msec (p less than .0001). T2 values of lesions had a smaller relative standard deviation than previously reported, and the range of T2 values of hemangiomas (119-181 msec) and metastases (68-103 msec) did not overlap. Our preliminary results suggest that T2 calculations with ultrafast MR imaging may be useful for differentiating hemangiomas from metastases. We hypothesize that T2 values obtained from ultrafast MR images are more reliable than those obtained from conventional MR images, primarily because of the elimination of T1 information and effects of motion on image signal intensity.
authors.affiliation: Department of Radiology, Massachusetts General Hospital, Boston 02114.
authors.forename: M A
authors.initials: MA
authors.lastname: Goldberg
authors.forename: S
authors.initials: S
authors.lastname: Saini
authors.forename: P F
authors.initials: PF
authors.lastname: Hahn
authors.forename: T K
authors.initials: TK
authors.lastname: Egglin
authors.forename: P R
authors.initials: PR
authors.lastname: Mueller
mesh_terms: D002276:Carcinoid Tumor / Q000473:pathology / Q000556:secondary; D003937:Diagnosis, Differential; D005069:Evaluation Studies as Topic; D006392:Hemangioma, Cavernous / Q000175:diagnosis*; D006801:Humans; D007414:Intestinal Neoplasms / Q000473:pathology; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000556:secondary; D008279:Magnetic Resonance Imaging / Q000379:methods*