title: [Malignant meningioma with lung metastases in a Boxer].
abstract: The rare case of a meningioma with pulmonary metastases in a dog is described. Clinically, the ten-year-old boxer bitch showed generalized seizures, strabismus and deficient proprioception. The post-mortem examination revealed a basically localized meningeal tumor, having the light- and electron-microscopic appearance of a malignant meningotheliomatous meningioma. Immunohistochemically, the tumor cells did not show any positive reaction with antibodies to GFAP, S-100 protein, NSE, vimentin, cytokeratin, desmin, and von Willebrand factor (factor VIII related antigen). Immunohistochemical examination of seven other canine meningiomas showed an identical pattern. The results and the relevant literature are discussed.
authors.affiliation: Lehrstuhl für Allgemeine Pathologie und Neuropathologie, Ludwig-Maximilians-Universität München.
authors.forename: P
authors.initials: P
authors.lastname: Schmidt
authors.forename: C
authors.initials: C
authors.lastname: Geyer
authors.forename: A
authors.initials: A
authors.lastname: Hafner
authors.forename: K
authors.initials: K
authors.lastname: Bise
authors.forename: W
authors.initials: W
authors.lastname: Hermanns
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000556:secondary / Q000662:veterinary*; D008577:Meningeal Neoplasms / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary*; D008579:Meningioma / Q000473:pathology / Q000556:secondary / Q000648:ultrastructure / Q000662:veterinary*; D008854:Microscopy, Electron
vernacular_title: Malignes Meningeom mit Lungenmetastasen bei einem Boxer.