[Hypersensitivity reactions to ethylenediamine].
Most allergic reactions to aminophylline are caused by hypersensitivity to ethylendiamine. We present 3 asthmatic patients, 2 of whom had immediate allergic symptoms after the administration of aminophylline. The third patient presented generalized erythrodermia 24 hours after receiving aminophylline. In all three cases sensitivity to ethylendiamine was observed in skin testing. These patients can tolerate other theophylline preparations not containing ethylendiamine.
Lleonart
R
R
Unidad de Alergia, Hospital de la Sta. Creu i Sant Pau, Barcelona.
Abadías
M
M
Monés
O
O
Jané
F
F
Olivé
A
A
Cisteró
A
A
D000368:Aged; D000628:Aminophylline / Q000009:adverse effects; D001249:Asthma / Q000150:complications / Q000188:drug therapy; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000209:etiology*; D005029:Ethylenediamines / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000139:chemically induced / Q000175:diagnosis; D006969:Hypersensitivity, Immediate / Q000139:chemically induced / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D012882:Skin Tests
D005029:Ethylenediamines; D000628:Aminophylline; C031234:ethylenediamine
Reacciones de hipersensibilidad a la etilendiamina.