Ultrasound properties of liver with and without particulate contrast agents.
Basic acoustic parameters are examined in rabbit liver with and without a solid contrast agent used for tumor detection. In normal liver, backscatter, attenuation, and sound speed are found to decrease with increasing water content. The addition of micron-sized particles made from iodipamide ethyl ester (IDE) can increase backscatter and attenuation depending on size and concentration. A discrepancy of the increased backscatter from theoretical predictions based on random scatterers is attributed to the particle's biodistribution in the liver.
Tuthill
T A
TA
Department of Electrical Engineering, University of Rochester, NY 14627.
Baggs
R B
RB
Violante
M R
MR
Parker
K J
KJ
D000042:Absorption; D000818:Animals; D003287:Contrast Media; D007089:Image Enhancement / Q000379:methods*; D008099:Liver / Q000000981:diagnostic imaging*; D010316:Particle Size; D011817:Rabbits; D013016:Sound; D014463:Ultrasonography
D003287:Contrast Media