title: Ultrasound properties of liver with and without particulate contrast agents.
abstract: Basic acoustic parameters are examined in rabbit liver with and without a solid contrast agent used for tumor detection. In normal liver, backscatter, attenuation, and sound speed are found to decrease with increasing water content. The addition of micron-sized particles made from iodipamide ethyl ester (IDE) can increase backscatter and attenuation depending on size and concentration. A discrepancy of the increased backscatter from theoretical predictions based on random scatterers is attributed to the particle's biodistribution in the liver.
authors.affiliation: Department of Electrical Engineering, University of Rochester, NY 14627.
authors.forename: T A
authors.initials: TA
authors.lastname: Tuthill
authors.forename: R B
authors.initials: RB
authors.lastname: Baggs
authors.forename: M R
authors.initials: MR
authors.lastname: Violante
authors.forename: K J
authors.initials: KJ
authors.lastname: Parker
mesh_terms: D000042:Absorption; D000818:Animals; D003287:Contrast Media; D007089:Image Enhancement / Q000379:methods*; D008099:Liver / Q000000981:diagnostic imaging*; D010316:Particle Size; D011817:Rabbits; D013016:Sound; D014463:Ultrasonography
chemical_list: D003287:Contrast Media