title: Quantitative histochemical study of secretory cells after short term tubal obstruction in the cat.
abstract: Quantitative histochemistry of goblet cells producing different types of glycoproteins was examined in cat middle ears with and without Euatachian tube obstruction (ETO). The goblet cell population significantly increased at 1 week after ETO and showed a tendency to decrease down to the normal level at 4 weeks after ETO. In the normal ears, approximately 85% of glycoprotein in the secretory cells were sulphated and 15% were neutral. ETO significantly increased goblet cell population containing sulphated glycoprotein at the expense of neutral glycoprotein. The results indicate that goblet cells can easily and within a short period be modified both in number and in intracellular glycoproteins by a tubal obstruction.
authors.affiliation: Department of Otorhinolaryngology, Mie University School of Medicine, Tsu, Japan.
authors.forename: C S
authors.initials: CS
authors.lastname: Jin
authors.forename: Y
authors.initials: Y
authors.lastname: Majima
authors.forename: Y
authors.initials: Y
authors.lastname: Hamaguchi
authors.forename: K
authors.initials: K
authors.lastname: Takeuchi
authors.forename: Y
authors.initials: Y
authors.lastname: Sakakura
mesh_terms: D000818:Animals; D002415:Cats; D003250:Constriction; D004432:Ear, Middle / Q000737:chemistry / Q000166:cytology* / Q000378:metabolism; D005064:Eustachian Tube / Q000473:pathology*; D006023:Glycoproteins / Q000032:analysis / Q000378:metabolism; D006651:Histocytochemistry; D009092:Mucous Membrane / Q000737:chemistry / Q000166:cytology / Q000378:metabolism; D010034:Otitis Media with Effusion / Q000473:pathology*; D013997:Time Factors
chemical_list: D006023:Glycoproteins