Sequence of the precursor of intestinal lactase-phlorizin hydrolase from fetal rat.
The nucleotide sequence of the cDNA corresponding to the precursor of fetal rat intestinal lactase-phlorizin hydrolase was determined. The precursor consists of four tandemly organized homologous domains flanked by a signal peptide in the N-terminal region and by a transmembrane peptide in the C-terminal region.
Duluc
I
I
INSERM U61, Strasbourg, France.
Boukamel
R
R
Mantei
N
N
Semenza
G
G
Raul
F
F
Freund
J N
JN
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D005333:Fetus / Q000201:enzymology; D007422:Intestines / Q000196:embryology / Q000201:enzymology*; D043322:Lactase; D010694:Lactase-Phlorizin Hydrolase / Q000235:genetics*; D008969:Molecular Sequence Data; D011498:Protein Precursors / Q000235:genetics*; D021382:Protein Sorting Signals / Q000235:genetics; D051381:Rats; D012689:Sequence Homology, Nucleic Acid; D001616:beta-Galactosidase / Q000378:metabolism
D011498:Protein Precursors; D021382:Protein Sorting Signals; D043322:Lactase; D001616:beta-Galactosidase; D010694:Lactase-Phlorizin Hydrolase