Reliability of two new test kits for rapid diagnosis of respiratory syncytial virus infection.
Two new rapid enzyme immunoassays (EIAs) for detecting respiratory syncytial virus (RSV), Directigen (Becton Dickinson Microbiology Systems) and TestPack (Abbott Diagnostics) were compared with virus isolation and direct immunofluorescence by using fresh specimens. The sensitivities of both EIAs were low (72 to 73%), but when initial specimens were used, TestPack had a high sensitivity (92%) in contrast to that of Directigen (76%). Because of its high sensitivity and specificity, TestPack can be used for diagnosis of RSV in acute disease.
Rothbarth
P H
PH
Department of Virology, University Hospital Rotterdam, The Netherlands.
Hermus
M C
MC
Schrijnemakers
P
P
D046508:Culture Techniques; D005455:Fluorescent Antibody Technique; D006801:Humans; D011933:Reagent Kits, Diagnostic; D015203:Reproducibility of Results; D012136:Respiratory Syncytial Viruses / Q000302:isolation & purification*; D010253:Respirovirus Infections / Q000175:diagnosis*; D012680:Sensitivity and Specificity
D011933:Reagent Kits, Diagnostic