Occupational asthma in bakeries caused by sensitivity to alpha-amylase.
We report on a patient with asthma induced by occupational exposure to alpha-amylase derived from Aspergillus oryzae, which is a component of bread additives. A type I hypersensitivity to this enzyme was demonstrated by means of skin test, immunoassay for specific IgE, and immediate bronchial provocation test response to an alpha-amylase extract.
Blanco Carmona
J G
JG
Sección de Alergología, Hospital General Yagüe, Burgos, Spain.
Juste Picón
S
S
Garcés Sotillos
M
M
D000328:Adult; D001236:Aspergillus oryzae; D001249:Asthma / Q000209:etiology* / Q000276:immunology; D001939:Bread; D001985:Bronchial Provocation Tests; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000209:etiology / Q000276:immunology; D007073:Immunoglobulin E / Q000032:analysis; D008297:Male; D009784:Occupational Diseases / Q000209:etiology* / Q000276:immunology; D012882:Skin Tests; D013030:Spain; D000516:alpha-Amylases / Q000009:adverse effects*
D007073:Immunoglobulin E; D000516:alpha-Amylases