[Gingival hyperplasia in a heart transplant patient treated with cyclosporin A and nifedipine].
Cyclosporin-A and Nifedipine-induced gingival enlargement have been reported to have similar clinical and histopathological features as phenytoin. The present case report describes the clinical course and treatment of a young heart-transplant patient who developed gingival hyperplasia under both Nifedipine and Cyclosporin-A. After withdrawing Nifedipine from his daily medication and a second step of surgical excision, the patient presents no recurrence of gingival enlargement, 6 months post-treatment despite his Cyclosporin-A regimen and poor oral hygiene.
Goffin
M
M
Emory University, U.L.B., Bruxelles.
D000293:Adolescent; D003524:Cyclosporins / Q000009:adverse effects* / Q000627:therapeutic use; D005885:Gingival Hyperplasia / Q000139:chemically induced* / Q000601:surgery; D016027:Heart Transplantation; D006801:Humans; D008297:Male; D009543:Nifedipine / Q000009:adverse effects* / Q000627:therapeutic use
D003524:Cyclosporins; D009543:Nifedipine
Hyperplasie gingivale chez un transplanté cardiaque traité par Ciclosporine-A et Nifédipine.