title: Medulloblastoma in adulthood.
abstract: Reporting 32 cases of medulloblastoma in patients aged 17 to 65 years and reviewing the major case-series in the literature, we analyze the clinicobiological and diagnostic features and treatment of this tumor in adulthood. We consider some factors that seem to have a favorable bearing on the prognosis: female sex, length of clinical history, tumor size, hemispheric site, and total removal followed by radiotherapy. We then discuss the differences in tumor behavior between adulthood and childhood that emerged from the comparative analysis.
authors.affiliation: Department of Neurological Sciences, University of Rome La Sapienza, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Ferrante
authors.forename: L
authors.initials: L
authors.lastname: Mastronardi
authors.forename: P
authors.initials: P
authors.lastname: Celli
authors.forename: M
authors.initials: M
authors.lastname: Acqui
authors.forename: L
authors.initials: L
authors.lastname: Cervoni
authors.forename: A
authors.initials: A
authors.lastname: Fortuna
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001932:Brain Neoplasms / Q000401:mortality* / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008527:Medulloblastoma / Q000401:mortality* / Q000532:radiotherapy / Q000601:surgery; D008875:Middle Aged; D011379:Prognosis; D016019:Survival Analysis