title: Gadopentetate dimeglumine-enhanced MR imaging in children following surgery for brain tumor: spectrum of meningeal findings.
abstract: Gadopentetate dimeglumine-enhanced MR imaging was performed in 51 consecutive postoperative pediatric neurosurgical patients with a diagnosis of brain tumor. These studies were examined retrospectively to determine the spectrum of meningeal findings in this patient population. Patterns of enhancement were correlated with type of surgery, interval since surgery, clinical and CSF findings, and the use of radiation and steroid therapies. Normal postoperative meningeal findings include no meningeal enhancement or mild focal or diffuse dural enhancement. More moderate dural or subdural enhancement may be seen in clinically well children who have postsurgical subdural collections, or who have a remote history of serious meningeal disease (meningitis or subarachnoid hemorrhage). In all six cases in which nodular dural, leptomeningeal, or ependymal enhancement was seen, recurrent local tumor, leptomeningeal metastases, or infection were present. Leptomeningeal tumor or infection should be suspected if such patterns of enhancement are noted. Parameters that did not appear to affect the pattern of meningeal enhancement included type of surgery, interval since surgery, or therapeutic radiation.
authors.affiliation: Department of Radiology, Emory University School of Medicine, Atlanta, GA 30322.
authors.forename: P A
authors.initials: PA
authors.lastname: Hudgins
authors.forename: P C
authors.initials: PC
authors.lastname: Davis
authors.forename: J C
authors.initials: JC
authors.lastname: Hoffman
mesh_terms: D000293:Adolescent; D001932:Brain Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D003287:Contrast Media; D005260:Female; D005500:Follow-Up Studies; D019786:Gadolinium DTPA; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008578:Meninges / Q000473:pathology*; D009942:Organometallic Compounds; D004369:Pentetic Acid; D011184:Postoperative Period
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA