title: The mechanisms of stone disintegration by shock waves.
abstract: Through interpretation of high-speed films at 10,000 frames per second of shock wave action on kidney stones and gallstones, the mechanism of stone destruction was analyzed in detail. This shows that the interaction of the shock wave with the targets firstly produces fissures in the stone material. Liquid then enters these small cracks. The actual disintegration is caused later by the enormous violence of imploding cavitation bubbles within these small split lines. That cavitation acts inside the stone and causes fragmentation even within the human gallbladder could furthermore be demonstrated by using scanning electron microscopy. These results should lead to a different process in gallstone lithotripsy leaving intervals between the shock wave treatments. This will allow the viscous bile fluids to occupy the fissures of the stones more completely and, therefore, should increase the cavitational activity on the subsequent treatment with shock pulses.
authors.affiliation: Department of Experimental Surgery, University of Kiel, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Sass
authors.forename: M
authors.initials: M
authors.lastname: Bräunlich
authors.forename: H P
authors.initials: HP
authors.lastname: Dreyer
authors.forename: E
authors.initials: E
authors.lastname: Matura
authors.forename: W
authors.initials: W
authors.lastname: Folberth
authors.forename: H G
authors.initials: HG
authors.lastname: Preismeyer
authors.forename: J
authors.initials: J
authors.lastname: Seifert
mesh_terms: D002769:Cholelithiasis / Q000473:pathology / Q000628:therapy*; D006801:Humans; D007669:Kidney Calculi / Q000473:pathology / Q000628:therapy*; D008096:Lithotripsy; D008855:Microscopy, Electron, Scanning; D010781:Photography / Q000379:methods