Neuro-endocrine cells--a new prognostic parameter in prostate cancer.
Neuro-endocrine cells are a recognised component of prostatic ducts and acini. Half of all clinically manifest cancers show neuro-endocrine differentiation. Occult carcinomas have a lower incidence of such differentiation. Neuro-endocrine cells are of major prognostic importance and appear more reliable in predicting patients' survival than do conventional histological grading systems.
Cohen
R J
RJ
Department of Anatomical Pathology, University of the Witwatersrand, Johannesburg, South Africa.
Glezerson
G
G
Haffejee
Z
Z
D000230:Adenocarcinoma / Q000473:pathology; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D009490:Neurosecretory Systems / Q000473:pathology*; D011379:Prognosis; D011467:Prostate / Q000473:pathology; D011471:Prostatic Neoplasms / Q000401:mortality / Q000473:pathology*