title: Glycoprotein synthesis and secretion: translation and targeting.
abstract: To establish and maintain organelle identity, the eucaryotic cell must be able to target newly synthesized proteins to the various cellular compartments. The specificity of this process appears to be generally mediated by the interaction of structural features of the transported proteins (sorting signals) with cellular proteins that bind these structures and mediate the targeted transport (sorting receptors). Although signals involved in the sorting into a variety of intracellular organelles as well as some (putative) receptor proteins have been identified, the sorting signals and receptors involved in the targeted transport of proteins to the cells surface are just beginning to evolve.
authors.affiliation: Institute für Biochemie, Universität Frankfurt, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Koch-Brandt
mesh_terms: D006023:Glycoproteins / Q000096:biosynthesis* / Q000235:genetics / Q000378:metabolism; D006801:Humans; D014176:Protein Biosynthesis; D011499:Protein Processing, Post-Translational
chemical_list: D006023:Glycoproteins