title: Histological changes in the nasal ventral conchae of piglets infected with Bordetella bronchiseptica.
abstract: Piglets infected intranasally with Bordetella bronchiseptica were injected with two fluorochrome markers. Transverse sections of undecalcified nasal conchae (cut between the third incisor and the third premolar teeth) were examined by microradiography and fluorescence microscopy; surface-stained sections were evaluated by light microscopy. The fluorescent surface of the nasal ventral conchae from the infected piglets was increased as compared with the controls. This was due to an increased amount of fluorescent mineralization fronts as well as to the presence of abnormal fluorescent areas within trabeculae. Trabecular mineral content of the microradiographs was irregular and varied from hypo- to hypermineralized. When compared with the corresponding surface-stained sections, no correlation could be made between the mineral content and the type of tissue. These findings suggest that an increased number of osteoblasts which secrete prebone matrix but are modified so that mineralization does not occur normally.
authors.affiliation: GREMIP (Groupe de Recherche sur les Maladies Infectieuses du Porc), Faculté de Médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, Québec.
authors.forename: B
authors.initials: B
authors.lastname: Martineau-Doizé
authors.forename: H
authors.initials: H
authors.lastname: Trépanier
authors.forename: G P
authors.initials: GP
authors.lastname: Martineau
mesh_terms: D000818:Animals; D001885:Bordetella Infections / Q000473:pathology / Q000662:veterinary*; D005456:Fluorescent Dyes; D008856:Microscopy, Fluorescence; D012222:Rhinitis, Atrophic / Q000473:pathology / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000473:pathology*; D014420:Turbinates / Q000473:pathology*
chemical_list: D005456:Fluorescent Dyes