title: Exaggerated prolactin response to thyrotropin-releasing hormone in infertile women with the luteinized unruptured follicle syndrome.
abstract: Ten cases of luteinized unruptured follicle (LUF) syndrome out of 250 women with unexplained infertility were detected on ultrasonography, giving a frequency of 4%. Hormonal analysis revealed lower serum progesterone levels at mid-luteal phase in LUF cases, suggesting a link between LUF syndrome and inadequate luteal phase. Prolactin response to thyrotropin-releasing hormone was exaggerated in LUF cases as compared with ovulatory cases. Aberrant prolactin release may be a contributory factor in the pathophysiology of the LUF syndrome.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kugu
authors.forename: Y
authors.initials: Y
authors.lastname: Taketani
authors.forename: K
authors.initials: K
authors.lastname: Kohda
authors.forename: M
authors.initials: M
authors.lastname: Mizuno
mesh_terms: D000858:Anovulation / Q000097:blood* / Q000523:psychology; D003338:Corpus Luteum / Q000503:physiopathology*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007247:Infertility, Female / Q000097:blood* / Q000523:psychology; D007986:Luteinizing Hormone / Q000097:blood; D006080:Ovarian Follicle / Q000503:physiopathology*; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood*; D013315:Stress, Psychological / Q000150:complications; D013577:Syndrome; D013973:Thyrotropin-Releasing Hormone
chemical_list: D011374:Progesterone; D013973:Thyrotropin-Releasing Hormone; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone