title: Neuro-endocrine cells--a new prognostic parameter in prostate cancer.
abstract: Neuro-endocrine cells are a recognised component of prostatic ducts and acini. Half of all clinically manifest cancers show neuro-endocrine differentiation. Occult carcinomas have a lower incidence of such differentiation. Neuro-endocrine cells are of major prognostic importance and appear more reliable in predicting patients' survival than do conventional histological grading systems.
authors.affiliation: Department of Anatomical Pathology, University of the Witwatersrand, Johannesburg, South Africa.
authors.forename: R J
authors.initials: RJ
authors.lastname: Cohen
authors.forename: G
authors.initials: G
authors.lastname: Glezerson
authors.forename: Z
authors.initials: Z
authors.lastname: Haffejee
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D009490:Neurosecretory Systems / Q000473:pathology*; D011379:Prognosis; D011467:Prostate / Q000473:pathology; D011471:Prostatic Neoplasms / Q000401:mortality / Q000473:pathology*