title: Current status and future perspectives in the prevention of coronary heart disease.
abstract: The causal role of the three major coronary heart disease (CHD) risk factors - elevated plasma cholesterol, elevated blood pressure, and smoking - has become established by a wealth of scientific information which has become importantly expanded during the last decade with regard to prevention and treatment of elevated blood pressure and cholesterol lowering. A comprehensive action for CHD prevention has to include a population strategy for the reduction of risk factor levels in the entire population, and high-risk strategy for the reduction of risk factor levels in asymptomatic high-risk individuals, as well as a risk factor intervention as part of secondary prevention and good clinical care of patients with symptomatic CHD. There is no conflict between population and high-risk strategies, but instead these two different strategies are complementary to each other.
authors.affiliation: Department of Medicine, University of Kuopio, Finland.
authors.forename: K
authors.initials: K
authors.lastname: Pyörälä
mesh_terms: D000328:Adult; D000368:Aged; D002784:Cholesterol / Q000097:blood; D003327:Coronary Disease / Q000453:epidemiology / Q000401:mortality / Q000517:prevention & control*; D005260:Female; D005544:Forecasting; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects
chemical_list: D002784:Cholesterol