Pulmonary function in a hospital population of asthmatic children.
Traditionally, assessment of control of pediatric asthma has relied on symptoms reported by the child and his or her family, and on clinical examination at office visits. A survey of the pulmonary function of 100 clinically stable asthmatic children, recruited from the outpatient clinics of the Royal Children's Hospital, Melbourne, Australia for a clinical drug trial was performed. Correlation of baseline pulmonary function with symptom scores recorded at home and home monitoring of peak expiratory flow variability (PEFV) found that a third of these clinically stable asthmatic children had an abnormal FEV1 and half had an abnormal FEF25-75; however, there was no correlation between symptom scores and FEV1 or PEFV. Objective measurements of pulmonary function are needed to ensure good asthma control. Home monitoring of peak expiratory flow can provide a valuable aid for the management of pediatric asthma.
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Department of Thoracic Medicine, Royal Children's Hospital, Victoria, Melbourne, Australia.
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D000280:Administration, Inhalation; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D000328:Adult; D001249:Asthma / Q000188:drug therapy / Q000503:physiopathology*; D002648:Child; D003692:Delayed-Action Preparations; D005541:Forced Expiratory Volume; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D010366:Peak Expiratory Flow Rate; D013566:Sympathomimetics / Q000008:administration & dosage / Q000627:therapeutic use; D013806:Theophylline / Q000008:administration & dosage / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D003692:Delayed-Action Preparations; D013566:Sympathomimetics; D013806:Theophylline