title: Reversible computerized tomographic lesion following childhood seizures.
abstract: Recently reversible computerized tomographic (CT) lesions following seizures have been reported, mostly in adult subjects. Focal CT lesions following seizures were recorded in 20 children. The distribution of the lesions was parietal in 17, frontal in two, occipital in one, and temporo-parietal in one. Multiple simultaneous lesions were observed in one child. Plain scan revealed evidence of cerebral oedema in 16 patients (mild 10, moderate four, and severe two). Enhanced scan showed a ring lesion in 12, hyperdense focus in five, and non-enhancing (hypodense) lesion in two children (excluding one child who had multiple lesions; three rings and one dense focus). These subjects were treated with anti-epileptic drugs only. Repeat CT scans yielded a complete resolution in 12 and a significant resolution in eight. It is concluded that in children with seizures, reversible CT demonstrable focal abnormalities may occur.
authors.affiliation: Department of Pediatrics, Maulana Azad Medical College, New Delhi, India.
authors.forename: H P
authors.initials: HP
authors.lastname: Sachdev
authors.forename: V K
authors.initials: VK
authors.lastname: Shiv
authors.forename: S K
authors.initials: SK
authors.lastname: Bhargava
authors.forename: A P
authors.initials: AP
authors.lastname: Dubey
authors.forename: P
authors.initials: P
authors.lastname: Choudhury
authors.forename: R K
authors.initials: RK
authors.lastname: Puri
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000627:therapeutic use*; D001929:Brain Edema / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D004828:Epilepsies, Partial / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy; D006801:Humans; D012640:Seizures / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed
chemical_list: D000927:Anticonvulsants