Immunoclinical correlation in diabetes mellitus. A preliminary report on the lectin-agglutination test.
Twenty cases with insulin dependent diabetes mellitus (IDDM) were studied and compared with a control group with non insulin dependent diabetes mellitus (NIDDM) and another group of nondiabetic healthy persons. Lymphocytes of each group were tested for agglutination with three sets of lectins: concavalin A (ConA), soyabean agglutinin (SBA) and peanut agglutinin (PNA). SBA test, being highly positive in IDDM and persistently negative in NIDDM, is the most significant of the three tests for differentiating between the two types of diabetes mellitus.
Mukherjee
N
N
Calcutta National Medical College.
Biswas
T K
TK
Mitra
S
S
Gupta
N
N
Sarkar
M
M
D000293:Adolescent; D000328:Adult; D000372:Agglutination Tests; D001327:Autoimmune Diseases / Q000175:diagnosis / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis* / Q000276:immunology; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis* / Q000276:immunology; D005260:Female; D006801:Humans; D037102:Lectins; D008297:Male; D008875:Middle Aged; D013601:T-Lymphocytes / Q000276:immunology
D037102:Lectins