title: Thyroid releasing hormone test in schizophrenic patients with post-psychotic depression.
abstract: 1. TSH response to TRH was assessed in 25 patients meeting operationalized criteria for the post-psychotic depression syndrome and in an age and sex matched control group of 34 primary depressed patients. 2. A blunted TSH response was observed in 36% of the patients with post-psychotic depression. 3. The rate of blunted TSH response was similar for patients with secondary post-psychotic depression to those patients with primary depressions. 4. Demographic and clinical parameters did not distinguish those post-psychotic depressed patients who had a blunted response from those who did not. 5. A blunted TSH response to TRH did not predict which patients were more likely to have a favorable response when adjunctive imipramine was added to their on-going fluphenazine decanoate and benztropine regimen.
authors.affiliation: Hillside Hospital, Division of Long Island Jewish Medical Center, Glen Oaks, N.Y.
authors.forename: S G
authors.initials: SG
authors.lastname: Siris
authors.forename: K
authors.initials: K
authors.lastname: Frechen
authors.forename: A
authors.initials: A
authors.lastname: Strahan
authors.forename: J
authors.initials: J
authors.lastname: Cutler
authors.forename: K
authors.initials: K
authors.lastname: Owen
authors.forename: J
authors.initials: J
authors.lastname: Alvir
authors.forename: T
authors.initials: T
authors.lastname: McCorry
mesh_terms: D000328:Adult; D003866:Depressive Disorder / Q000175:diagnosis* / Q000209:etiology; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use; D008297:Male; D012559:Schizophrenia / Q000150:complications / Q000175:diagnosis*; D013973:Thyrotropin-Releasing Hormone
chemical_list: D013973:Thyrotropin-Releasing Hormone; D007099:Imipramine