title: Bhattacharya: a new application for quality control.
abstract: The Bhattacharya method and the 'average of normals' method for internal quality control were compared. Both are based on unselected patient test results. The Bhattacharya method is mostly used in clinical chemistry for calculation of reference intervals but could be modified for quality control procedures. Using the data of a coagulation test and stimulating systematic errors, it was concluded that the Bhattacharya method is more sensitive to expected shifts and is more flexible than the 'average of normals' method.
authors.affiliation: Diakonessenhuis Refaja, Dordrecht, The Netherlands.
authors.forename: W P
authors.initials: WP
authors.lastname: Oosterhuis
authors.forename: T A
authors.initials: TA
authors.lastname: Modderman
authors.forename: R B
authors.initials: RB
authors.lastname: Dinkelaar
authors.forename: A H
authors.initials: AH
authors.lastname: Zwinderman
authors.forename: H J
authors.initials: HJ
authors.lastname: van der Helm
mesh_terms: D001780:Blood Coagulation Tests / Q000379:methods; D016000:Cluster Analysis; D006801:Humans; D008722:Methods; D016011:Normal Distribution; D011786:Quality Control; D011933:Reagent Kits, Diagnostic; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D011933:Reagent Kits, Diagnostic