title: Results of surgery for extratemporal partial epilepsy that began in childhood.
abstract: Thirty-five consecutive patients who underwent surgery for intractable extratemporal seizures originating in childhood are described. Candidates for surgery were selected on the basis of clinical criteria, neurodiagnostic imaging, and an electroencephalographic investigation that included the use of sphenoidal electrodes and long-term monitoring. Invasive preoperative monitoring was not used. Our results, with respect to the control of seizures and behavioral improvement, are comparable with series in which data from invasive recordings were used in the selection process. Sixty-three percent of the 35 patients (76.5% of those operated on after the introduction of long-term electroencephalographic monitoring) became either seizure free or experienced a reduction in their frequency of seizures by at least 75%. The favorable outcome in this group of patients strengthens the argument for early operation in children with intractable epilepsy, even when the seizure focus is outside the temporal lobe.
authors.affiliation: Department of Surgery, (Neurosurgery), Stanford University Medical School, Calif.
authors.forename: J
authors.initials: J
authors.lastname: Adler
authors.forename: G
authors.initials: G
authors.lastname: Erba
authors.forename: K R
authors.initials: KR
authors.lastname: Winston
authors.forename: K
authors.initials: K
authors.lastname: Welch
authors.forename: C T
authors.initials: CT
authors.lastname: Lombroso
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000627:therapeutic use; D001927:Brain Diseases / Q000150:complications; D001932:Brain Neoplasms / Q000150:complications; D002540:Cerebral Cortex / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D004828:Epilepsies, Partial / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D005260:Female; D005625:Frontal Lobe; D006801:Humans; D008297:Male; D011859:Radiography; D013702:Temporal Lobe; D013997:Time Factors
chemical_list: D000927:Anticonvulsants