title: The Ras superfamilies: regulatory proteins and post-translational modifications.
abstract: The Ras-like GTP-binding proteins comprise a large superfamily of proteins that play key roles in a wide variety of cellular activities, including cell growth, differentiation, secretion, and protein trafficking. During the past few years, it has become clear that these GTP-binding proteins are regulated by a variety of manners, including interactions with specific types of regulatory proteins and post-translational modification events.
authors.affiliation: Department of Cell Biology, Genentech Inc., South San Francisco, California 94080.
authors.forename: T
authors.initials: T
authors.lastname: Evans
authors.forename: M J
authors.initials: MJ
authors.lastname: Hart
authors.forename: R A
authors.initials: RA
authors.lastname: Cerione
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D019204:GTP-Binding Proteins / Q000378:metabolism*; D020690:GTPase-Activating Proteins; D011905:Genes, ras / Q000502:physiology*; D006801:Humans; D008969:Molecular Sequence Data; D011499:Protein Processing, Post-Translational; D011506:Proteins / Q000378:metabolism; D020703:ras GTPase-Activating Proteins
chemical_list: D020690:GTPase-Activating Proteins; D011506:Proteins; D020703:ras GTPase-Activating Proteins; D019204:GTP-Binding Proteins