Comparison of three species of dietary fish: effects on serum concentrations of low-density-lipoprotein cholesterol and apolipoprotein in normotriglyceridemic subjects.
Limited information is available comparing the effect of different species of fish on serum low-density-lipoprotein-cholesterol (LDL-C) and apolipoprotein B (apo B) concentrations. We fed 21 normotriglyceridemic males diets containing different species of fish (200 g Dover sole, Chinook salmon, or sablefish) for 18 d in a three-period crossover design. Concentrations of apo B and LDL-C rose on the salmon and sablefish diets compared with the sole diet (P = 0.02 for apo B, 0.08 for LDL-C). These increases were parallel to each other: apo B rose 14% and LDL-C rose 16% on the salmon diet and 17% and 14%, respectively, on the sablefish diet compared with the diet consumed before the study. These results suggest that the consumption of fish with a moderate amounts of n-3 fatty acids may cause a deleterious rise in LDL-C and apo B concentrations in normotriglyceridemic males.
Gerhard
G T
GT
Department of Nutrition and Food Management, Oregon State University, Corvallis 97331-5103.
Patton
B D
BD
Lindquist
S A
SA
Wander
R C
RC
D000818:Animals; D001055:Apolipoproteins B / Q000097:blood; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000097:blood; D001792:Blood Platelets / Q000378:metabolism; D008078:Cholesterol, LDL / Q000097:blood*; D004032:Diet; D015118:Eicosapentaenoic Acid / Q000097:blood; D005227:Fatty Acids / Q000097:blood; D005395:Fish Oils / Q000008:administration & dosage*; D005399:Fishes; D005412:Flatfishes; D006801:Humans; D008297:Male; D012474:Salmon; D014280:Triglycerides / Q000097:blood*
D001055:Apolipoproteins B; D001095:Arachidonic Acids; D008078:Cholesterol, LDL; D005227:Fatty Acids; D005395:Fish Oils; D014280:Triglycerides; D016718:Arachidonic Acid; D015118:Eicosapentaenoic Acid