Nonleast-squares jackknife regression in drug design.
Nonleast-squares jackknife regression was applied to model a quantitative structure-activity relationship (QSAR) analysis of butyrophenones. Dependent physicochemical and dependent psychopharmacological parameters were correlated, and the robustness of the model was confirmed by resampling.
Mager
P P
PP
Research Group for Pharmacochemistry, Faculty of Medicine, University Johannisallee 32, Leipzig, Germany.
D000465:Algorithms; D000818:Animals; D002090:Butyrophenones / Q000737:chemistry; D004285:Dogs; D004333:Drug Administration Routes; D015195:Drug Design; D051381:Rats; D012044:Regression Analysis; D013329:Structure-Activity Relationship
D002090:Butyrophenones