title: Antifungal activity and mode of action of saponins from Madhuca butyracea Macb.
abstract: The antifungal activity of saponins isolated as a byproduct from the defatted cake of M. butyracea oil seed is reported. The inhibitory concentrations against plant pathogenic fungi ranged from 500 to 2000 ppm. Maximum sensitivity to saponins was shown by Penicillium expansum. Cephalosporium acrimonium, Helminthosporium oryzae and Trichoderma viride. The saponins caused leakage of cell components and underwent degradation by fungus, Trichoderma viride. The usefulness of saponins as antimycotic agents is discussed.
authors.affiliation: Department of Medicine and Physiology, School of Medicine, University of Miami, Florida 33101.
authors.forename: T
authors.initials: T
authors.lastname: Lalitha
authors.forename: L V
authors.initials: LV
authors.lastname: Venkataraman
mesh_terms: D000935:Antifungal Agents / Q000302:isolation & purification; D005658:Fungi / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology*; D012503:Saponins / Q000302:isolation & purification / Q000494:pharmacology*; D014242:Trichoderma / Q000187:drug effects
chemical_list: D000935:Antifungal Agents; D010936:Plant Extracts; D012503:Saponins