title: Medical considerations for human exposure to acceleration-induced loss of consciousness.
abstract: Unconsciousness in humans has probably been occurring since before recorded history. Acceleration-induced loss of consciousness (G-LOC) in flight has been occurring since 1919. Loss of consciousness and syncope are common occurrences in clinical medicine with G-LOC, occurring in a large number of aircrew and research subjects during centrifuge exposures. Although the major risk to humans exposed to centrifuge-induced G-LOC is related directly to the central nervous, cardiac, and musculoskeletal (neck and back) systems, other risks are also present. Human exposure to G-LOC is required to help solve the G-LOC problem in aviators. To perform such human research, the benefits must clearly outweigh the risks to the human. Even if the risk-benefit ratio is considered favorably balanced, continued monitoring of individuals exposed to G-LOC is mandatory. To facilitate monitoring of humans exposed to G-LOC, a central nervous system (CNS) insult classification system would be of significant value. A suggested classification scheme which considers the type of CNS insult, the history of exposure to G-LOC, and the temporal evolution of potential CNS insult is developed. To date there is no indication that G-LOC episodes have any associated long term or persistent psychophysiological sequelae. Improved acute and long term evaluation of humans exposed to G-LOC are, however, important aspects of conducting G-LOC research with humans. Such research and careful monitoring are necessary to understand and eventually solve the G-LOC problem in aviators.
authors.affiliation: Naval Air Development Center, Warminster, PA 18974.
authors.forename: J E
authors.initials: JE
authors.lastname: Whinnery
mesh_terms: D000054:Acceleration; D000337:Aerospace Medicine; D000818:Animals; D002490:Central Nervous System / Q000503:physiopathology; D004195:Disease Models, Animal; D006801:Humans; D012106:Research; D012307:Risk Factors; D013575:Syncope / Q000503:physiopathology; D014474:Unconsciousness / Q000503:physiopathology*