title: Preoperative localization of enlarged parathyroid glands with ultrasonically guided fine needle aspiration for parathyroid hormone assay.
abstract: For preoperative localization of enlarged parathyroid glands, several imaging techniques have been used. In this study we demonstrate the feasibility of using ultrasonography with fine needle aspiration for parathyroid hormone assay as a preoperative localization procedure in 21 patients with primary hyperparathyroidism. A single adenoma was found in 18 patients while 3 patients had multiglandular disease. Ultrasonically guided fine needle biopsy was possible in 11 cases. In 8 of these aspirates, a high parathyroid hormone content was found. In all 8 cases the localization was confirmed at surgery. We conclude that the efficiency to preoperatively localize enlarged parathyroid glands is enhanced by fine needle aspiration.
authors.affiliation: Department of Surgery, University Hospital, Lund, Sweden.
authors.forename: A
authors.initials: A
authors.lastname: Bergenfelz
authors.forename: L
authors.initials: L
authors.lastname: Forsberg
authors.forename: E
authors.initials: E
authors.lastname: Hederström
authors.forename: B
authors.initials: B
authors.lastname: Ahrén
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000379:methods; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000000981:diagnostic imaging / Q000378:metabolism / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010280:Parathyroid Glands / Q000737:chemistry / Q000000981:diagnostic imaging* / Q000601:surgery; D010281:Parathyroid Hormone / Q000032:analysis*; D014463:Ultrasonography
chemical_list: D010281:Parathyroid Hormone