The role of hepatic metabolites of benzene in bone marrow peroxidase-mediated myelo- and genotoxicity.
Kalf
G
G
Department of Biochemistry and Molecular Biology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
Shurina
R
R
Renz
J
J
Schlosser
M
M
D000818:Animals; D001554:Benzene / Q000378:metabolism / Q000633:toxicity*; D016227:Benzoquinones / Q000493:pharmacokinetics; D001711:Biotransformation; D001853:Bone Marrow / Q000187:drug effects* / Q000378:metabolism; D006801:Humans; D006873:Hydroquinones / Q000493:pharmacokinetics; D009153:Mutagens; D010544:Peroxidases / Q000378:metabolism; D019800:Phenol; D010636:Phenols / Q000493:pharmacokinetics; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism
D016227:Benzoquinones; D006873:Hydroquinones; D009153:Mutagens; D010636:Phenols; D019800:Phenol; C004532:quinone; D010544:Peroxidases; D011451:Prostaglandin-Endoperoxide Synthases; D001554:Benzene; C031927:hydroquinone