title: [Assessment of conformation changes of immunoglobulin G molecules using a fluorescent probe].
abstract: A proximate method for conformational changes detection in immunoglobulin G preparations used in research and medical practice is introduced. This method is based on the measurement of IgG-connected 1,8-anilinenaphtalenesulphonate fluorescent probe (ANS) time of damping. When the protein structure is broken fluorescence damping time of IgG-connected ANS rises up.
authors.forename: N P
authors.initials: NP
authors.lastname: Pupyrev
authors.forename: N A
authors.initials: NA
authors.lastname: Matveeva
authors.forename: V Iu
authors.initials: VIu
authors.lastname: Naumenko
authors.forename: F F
authors.initials: FF
authors.lastname: Karpov
mesh_terms: D000817:Anilino Naphthalenesulfonates / Q000737:chemistry; D005456:Fluorescent Dyes; D007074:Immunoglobulin G / Q000737:chemistry*; D011487:Protein Conformation
chemical_list: D000817:Anilino Naphthalenesulfonates; D005456:Fluorescent Dyes; D007074:Immunoglobulin G; C027132:1-anilino-8-naphthalenesulfonate
vernacular_title: Otsenka konformatsionnykh izmeneniĭ molekul immunoglobulina G s pomoshch'iu fluorestsentnogo zonda.