title: Scintigraphy with 99mTc-HMPAO labeled leukocytes in acute cholecystitis.
abstract: 99mTc-HMPAO labeled leukocyte scanning was performed on 38 patients with clinically suspected acute cholecystitis (AC) to evaluate its diagnostic value. The typical finding was an increasing accumulation of the tracer in the gallbladder wall in a 4 hour series of scintigrams. Leukocyte scan was positive in 16 of 17 patients with surgically and histologically confirmed AC. There were no false-positive findings. The sensitivity, specificity, and accuracy of scintigraphy were 94, 100, and 96%, respectively. In 2 patients with acute acalculous cholecystitis true-positive findings were observed. Scintigraphy with 99mTc-HMPAO labeled leukocytes is a valuable new imaging method in AC.
authors.affiliation: Department of Radiology, Päijät-Häme Central Hospital, Lahti, Finland.
authors.forename: E
authors.initials: E
authors.lastname: Lantto
authors.forename: K
authors.initials: K
authors.lastname: Järvi
authors.forename: R
authors.initials: R
authors.lastname: Laitinen
authors.forename: T
authors.initials: T
authors.lastname: Lantto
authors.forename: M
authors.initials: M
authors.lastname: Taavitsainen
authors.forename: I
authors.initials: I
authors.lastname: Talvitie
authors.forename: M
authors.initials: M
authors.lastname: Vorne
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000032:analysis; D002764:Cholecystitis / Q000097:blood / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007962:Leukocytes; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D010091:Oximes; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D019690:Technetium Tc 99m Exametazime
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D002097:C-Reactive Protein