title: Oxygen saturation during third molar removal with local anaesthetic alone and in combination with intravenous sedation.
abstract: Oxygen saturation was recorded in 96 adults undergoing removal of third molar teeth in the dental surgery. Half the patients received local anaesthetic alone; the remainder received, in addition, intravenous midazolam. Patients receiving sedation sustained the greatest falls in oxygen saturation. However, in 10 out of 48 patients undergoing third molar removal with LA alone, oxygen saturations in the range of 93-89% were recorded. The results of this study suggest that all patients undergoing removal of third molars are at risk of hypoxia. Short episodes of hypoxia may be of little consequence in healthy patients, but in compromised patients early detection may avoid serious complications.
authors.affiliation: Department of Oral and Maxillofacial Surgery, University of Sheffield, School of Clinical Dentistry.
authors.forename: T
authors.initials: T
authors.lastname: Lowe
authors.forename: I M
authors.initials: IM
authors.lastname: Brook
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D000766:Anesthesia, Dental / Q000009:adverse effects*; D000771:Anesthesia, Intravenous / Q000009:adverse effects; D000772:Anesthesia, Local / Q000009:adverse effects*; D016292:Procedural Sedation / Q000009:adverse effects*; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000209:etiology*; D008297:Male; D008874:Midazolam / Q000008:administration & dosage / Q000009:adverse effects*; D008964:Molar, Third / Q000601:surgery*; D010092:Oximetry; D010100:Oxygen / Q000097:blood; D014081:Tooth Extraction
chemical_list: D008874:Midazolam; D010100:Oxygen