Involvement of chromosome 5 in large bowel cancer.
We present here 3 of 30 cases of large bowel cancer cytogenetically studied, with deletion of chromosome 5. One of them presented a terminal deletion and the other two an interstitial deletion of chromosome 5q. In all three cases the segment 5q12-22 was deleted. Our findings may show that the segment 5q12-22 is important for a subgroup of colorectal cancers.
Panani
A D
AD
Second Department of Internal Medicine, Propaedeutic of Athens University, Evangelismos Hospital, Greece.
Ferti-Passantonopoulou
A
A
Raptis
S
S
D000230:Adenocarcinoma / Q000235:genetics*; D002869:Chromosome Aberrations / Q000235:genetics*; D002871:Chromosome Banding; D002872:Chromosome Deletion; D025063:Chromosome Disorders; D002895:Chromosomes, Human, Pair 5; D015179:Colorectal Neoplasms / Q000235:genetics*; D006801:Humans