Psychiatric symptoms as features of systemic lupus erythematosus.
An enquiry of the Dutch Lupus Patients Society revealed that 49% of the members had experienced psychiatric symptoms before systemic lupus erythematosus (SLE) was diagnosed and 33% had sought professional psychiatric help at that stage. To determine the frequency of SLE on psychiatric admission 2,121 patients were tested for the presence of SLE-specific antinuclear and anti-DNA autoantibodies. The results suggest that SLE is a cause of admission in psychiatric hospitals at the rate of 0.1-0.2% and routine screening of antinuclear and anti-DNA antibodies on admission is not an effective diagnostic approach.
van Dam
A P
AP
Central Laboratory, The Netherlands Red Cross Blood Transfusion Service, Amsterdam.
Wekking
E M
EM
Oomen
H A
HA
D000328:Adult; D000368:Aged; D000974:Antibodies, Antinuclear / Q000302:isolation & purification; D006778:Hospitals, Psychiatric; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000276:immunology; D001523:Mental Disorders / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D008875:Middle Aged; D009483:Neuropsychological Tests; D015995:Prevalence; D011795:Surveys and Questionnaires
D000974:Antibodies, Antinuclear