title: Gemfibrozil-induced myopathy.
abstract: Drug-induced myopathy has been reported with use of lovastatin, nicotinic acid, and clofibrate. A particularly severe form, often accompanied by rhabdomyolysis, has been reported with the use of lovastatin and gemfibrozil; however, as far as we know, no case has been documented with use of gemfibrozil alone. Herein, we report the first case (to our knowledge of gemfibrozil-induced myopathy, confirmed by drug rechallenge.
authors.affiliation: Division of General Internal Medicine, Oregon Health Sciences University, Portland.
authors.forename: G J
authors.initials: GJ
authors.lastname: Magarian
authors.forename: L M
authors.initials: LM
authors.lastname: Lucas
authors.forename: C
authors.initials: C
authors.lastname: Colley
mesh_terms: D002994:Clofibrate / Q000009:adverse effects; D004359:Drug Therapy, Combination; D015248:Gemfibrozil / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D015228:Hypertriglyceridemia / Q000188:drug therapy; D008148:Lovastatin / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000139:chemically induced*
chemical_list: D008148:Lovastatin; D002994:Clofibrate; D015248:Gemfibrozil