[Effect of betaxolol and timolol on visual fields in glaucoma patients].
In a prospective, randomized, double-masked study, primary open-angle glaucoma patients were treated twice daily with either betaxolol 0.5% or timolol 0.5%. Patients received a pretreatment baseline examination following a 2 week washout period; they were then examined after 3 and 6 months of treatment. Each examination included visual field measurements with an Octopus automated perimeter and intraocular pressure measurement. The visual fields of the betaxolol group showed on the average a pronounced tendency toward improvement (MD decrease of 2.05 dB); visual fields in the timolol group showed a slight tendency toward improvement (MD decrease of 1.56 dB). The difference between these 2 trends after 6 months was statistically not significant (p greater than or equal to 0.05, U-test). Both drugs lowered intraocular pressure, there was no significant difference between the two drugs (p greater than or equal to 0.05, U-test).
Messmer
C
C
Kantonsspital Luzern Augenklinik.
Stümpfig
D
D
Flammer
J
J
D015784:Betaxolol / Q000008:administration & dosage*; D004311:Double-Blind Method; D005902:Glaucoma, Open-Angle / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D009883:Ophthalmic Solutions; D011446:Prospective Studies; D013999:Timolol / Q000008:administration & dosage*; D014794:Visual Fields / Q000187:drug effects*
D009883:Ophthalmic Solutions; D013999:Timolol; D015784:Betaxolol
Einfluss von Betaxolol und Timolol auf das Gesichtsfeld bei Glaukompatienten.