title: [Effect of thrombolytic therapy in acute myocardial infarct on incidence of ventricular late potentials].
abstract: The aim of thrombolytic therapy for acute myocardial infarction is reperfusion of the infarction-related vessel. Ventricular late potentials detected by signal averaging have been demonstrated to be related to slow and inhomogeneous conduction within damaged cardiac tissue. In 75 patients with first myocardial infarction the effect of thrombolysis on ventricular late potentials was studied. Reperfusion of the infarction-related vessel could be demonstrated by coronary angiography in 53 (71%) patients. In 22 patients (29%) there was no reperfusion. In the 53 patients with successful thrombolysis the incidence of late potentials was significantly lower (9%) than in the 22 patients without reperfusion (50%). The lower incidence of late potentials may demonstrate improved ventricular electrical stability.
authors.affiliation: Abteilung für Kardiologie, Zentrum Innere Medizin, Universitätsklinikum Göttingen.
authors.forename: S
authors.initials: S
authors.lastname: Brune
authors.forename: U
authors.initials: U
authors.lastname: Tebbe
authors.forename: J
authors.initials: J
authors.lastname: Wojcik
authors.forename: B D
authors.initials: BD
authors.lastname: Gonska
authors.forename: H
authors.initials: H
authors.lastname: Kreuzer
mesh_terms: D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000503:physiopathology; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000187:drug effects / Q000503:physiopathology; D004562:Electrocardiography / Q000187:drug effects*; D005260:Female; D005343:Fibrinolytic Agents; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology / Q000628:therapy*; D010960:Plasminogen Activators / Q000008:administration & dosage*; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage*
chemical_list: D005343:Fibrinolytic Agents; D010960:Plasminogen Activators; D014568:Urokinase-Type Plasminogen Activator
vernacular_title: Einfluss der thrombolytischen Therapie beim akuten Myokardinfarkt auf das Auftreten von ventrikulären Spätpotentialen.