Reciprocal cellular and humoral immune responses in bovine tuberculosis.
A sandwich ELISA for the detection of gamma interferon showed higher sensitivity and specificity than an indirect ELISA for mycobacterial antibodies in the diagnosis of bovine tuberculosis. Circumstantial evidence of an inverse relationship between cellular and humoral immune responses to Mycobacterium bovis was found in cattle with natural infection.
Ritacco
V
V
National University of Luján, Buenos Aires, Argentina.
López
B
B
De Kantor
I N
IN
Barrera
L
L
Errico
F
F
Nader
A
A
D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis* / Q000097:blood; D002417:Cattle; D004797:Enzyme-Linked Immunosorbent Assay; D007111:Immunity, Cellular; D007371:Interferon-gamma / Q000032:analysis*; D009163:Mycobacterium bovis / Q000276:immunology*; D011237:Predictive Value of Tests; D014373:Tuberculin / Q000276:immunology; D014380:Tuberculosis, Bovine / Q000175:diagnosis / Q000276:immunology*
D000907:Antibodies, Bacterial; D014373:Tuberculin; D007371:Interferon-gamma