Chiasmatic optic glioma.
Optic nerve glioma is a rare tumor usually occurring in small children. How these tumors should be treated, is a matter of controversy. Recommended treatment ranges from a wait-and-see policy to radical excision with or without subsequent radio- or chemotherapy. Comparative data on these lesion are limited, as there are no randomized investigations and long-term studies reported in the literature. In 11 patients interstitial radiotherapy was carried out, by the implantation of J-125 seeds following confirmation of the histological diagnosis. The results are compared with those of 10 patients who underwent only biopsy for histological confirmation. CT-stereotactic biopsy to verify the diagnosis with subsequent interstitial irradiation is presented as an alternative therapy for optic gliomas.
Mohadjer
M
M
Department of Neurosurgery, University of Freiburg, Federal Republic of Germany.
Etou
A
A
Milios
E
E
Baden
R
R
Mundinger
F
F
D000293:Adolescent; D000328:Adult; D001254:Astrocytoma / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D001706:Biopsy; D001918:Brachytherapy / Q000379:methods; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003390:Cranial Nerve Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D009897:Optic Chiasm / Q000473:pathology / Q000528:radiation effects / Q000601:surgery*
D007457:Iodine Radioisotopes