[The protective activity of 2 normal immunoglobulin preparations for intravenous administration in experimental Pseudomonas aeruginosa infection].
The antibody levels in 18 batches of the preparations of human immunoglobulin, Immunovenin and Immunovenin-Intact, for intravenous injection were determined in the enzyme immunoassay with the use of the mixture of P. aeruginosa lipopolysaccharide antigens of seven immunotypes. The average antibody titers in these preparations were identical. The preparations were found to have protective action against P. aeruginosa experimental infection in mice.
Vasilev
Ch L
ChL
Veleva
K V
KV
Tekelieva
R Kh
RKh
Pencheva
P I
PI
D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis; D004353:Drug Evaluation, Preclinical; D006801:Humans; D007116:Immunization, Passive; D007124:Immunoenzyme Techniques; D007128:Immunoglobulin Fragments / Q000008:administration & dosage* / Q000032:analysis; D007074:Immunoglobulin G / Q000008:administration & dosage* / Q000032:analysis; D007275:Injections, Intravenous; D008070:Lipopolysaccharides / Q000276:immunology; D051379:Mice; D011552:Pseudomonas Infections / Q000276:immunology / Q000517:prevention & control*; D011550:Pseudomonas aeruginosa / Q000276:immunology
D000907:Antibodies, Bacterial; D007128:Immunoglobulin Fragments; D007074:Immunoglobulin G; D008070:Lipopolysaccharides
Protektivnaia aktivnost' dvukh normal'nykh immunoglobulinovykh preparatov dlia vnutrivennogo vvedeniia pri éksperimental'noĭ sinegnoĭnoĭ infektsii.