title: [Melanoma metastatic to the trachea and nasal cavity: description of a case and review of the literature].
abstract: Secondary tumors of the trachea are exceedingly rare, only 14 cases having been reported in the literature. Moreover, metastatic involvement of naso-paranasal cavities can be considered quite unusual. Approximately 150 cases have been drawn from the literature, most of which presented a metastatic deposit from a renal adenocarcinoma. Report is then made of a case of cutaneous melanoma metastatic to the trachea and nasal cavity. The tracheal lesion was repeatedly treated with Nd Yag laser, whereas no treatment was considered eligible for nasal metastasis. The patient succumbed to the tumor 16 months after diagnosis of tracheal involvement had been made. The tendency for malignant melanomas to metastasize to distant organs via the bloodstream is well known, yet trachea and nasoparanasal involvement by metastatic melanoma has been reported, respectively, in only three and six cases, including the present one. Prognosis is unfavorable due to the unusual coexistence of metastases to other organs and the lack of an adequate treatment.
authors.affiliation: Istituto di Clinica Otorinolaringoiatrica, dell'Università di Brescia.
authors.forename: P
authors.initials: P
authors.lastname: Nicolai
authors.forename: G
authors.initials: G
authors.lastname: Peretti
authors.forename: J
authors.initials: J
authors.lastname: Cappiello
authors.forename: G
authors.initials: G
authors.lastname: Renaldini
authors.forename: S
authors.initials: S
authors.lastname: Cavaliere
authors.forename: M L
authors.initials: ML
authors.lastname: Morassi
mesh_terms: D006801:Humans; D008297:Male; D008545:Melanoma / Q000473:pathology / Q000556:secondary*; D008875:Middle Aged; D009666:Nose / Q000473:pathology; D009669:Nose Neoplasms / Q000473:pathology / Q000556:secondary*; D011379:Prognosis; D012878:Skin Neoplasms / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014132:Trachea / Q000473:pathology; D014134:Tracheal Neoplasms / Q000473:pathology / Q000556:secondary*
vernacular_title: Melanoma metastatico alla trachea e alla cavità nasa-le: descrizione di un caso e revisione della letteratura.