title: [Level of R-proteins in blood during development of diabetes mellitus].
abstract: R-proteins were studied in children with diabetes mellitus and in the risk group. The highest titre of the pattern was found in the children group where diabetes was the first to be detected. Normalization of the R-proteins high titre after insulin therapy was more typical for patients with first detected diabetes as compared with children impaired by the disease within 1-2 years. Content of immunoreactive insulin and titre of R-proteins correlated in the risk group. Estimation of the R-proteins titre simultaneously with other markers may be used for early diagnosis of diabetes mellitus as well as in control of the disease compensation.
authors.forename: V P
authors.initials: VP
authors.lastname: Fedotov
authors.forename: A V
authors.initials: AV
authors.lastname: Chernushkina
authors.forename: L N
authors.initials: LN
authors.lastname: Shcherbacheva
authors.forename: L M
authors.initials: LM
authors.lastname: Bartova
authors.forename: N N
authors.initials: NN
authors.lastname: Kulagina
authors.forename: A Ia
authors.initials: AIa
authors.lastname: Kul'berg
mesh_terms: D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D007328:Insulin / Q000097:blood / Q000627:therapeutic use; D009687:Nuclear Proteins / Q000097:blood*; D012307:Risk Factors
chemical_list: D007328:Insulin; D009687:Nuclear Proteins
vernacular_title: Uroven' R-belkov v krovi pri razvitii sakharnogo diabeta.