title: [Analysis of 1410 examinations of fetal pathology at the University Hospitals of Bordeaux].
abstract: We present a retrospective study of 1,410 fetal pathological examinations performed in the department of pathology of the CHU de Bordeaux. Initially, the recruitment of the cases was limited to the three maternity units of the CHU. Public and private maternities and departments of pediatrics from the whole of Aquitaine (S.W. province) as well as a certain number of neighbouring provinces now send us their material for analysis. Fetal pathological examination is systematically indicated in cases concerning spontaneous abortion, pregnancies terminated after prenatal diagnosis and stillbirths. Autopsies performed on children aged from 0 to 1 year have been included. The same technique has been used for all examinations and the data have been recorded on a computerized system (Centre Régional d'Informatique Hospitalière). Current data analysis for age at death, sex-ratio, maternal age, mode of abortion and pathological conditions are given. We found at least one pathological anomaly in 43.2% of the spontaneously aborted fetuses and stillbirths. Nevertheless, our aim is to demonstrate that foetopathology units can play a role not only for diagnoses having a significant impact on genetic counseling, but also as a database for epidemiological studies.
authors.affiliation: Unité de Foetopathologie, CHU Pellegrin, Bordeaux.
authors.forename: D
authors.initials: D
authors.lastname: Carles
authors.forename: F
authors.initials: F
authors.lastname: Serville
authors.forename: E M
authors.initials: EM
authors.lastname: Alberti
authors.forename: W
authors.initials: W
authors.lastname: Weichhold
mesh_terms: D001344:Autopsy / Q000592:standards / Q000706:statistics & numerical data*; D000013:Congenital Abnormalities / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology*; D016208:Databases, Factual; D005602:France / Q000453:epidemiology; D005820:Genetic Testing; D006302:Health Services Research; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008423:Maternal Age; D010337:Pathology Department, Hospital / Q000592:standards / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors
vernacular_title: Analyse de 1,410 examens foetopathologiques pratiqués au CHU de Bordeaux.