title: [Endoscopy, shockwave lithotripsy and local lysis in complicated pigmentary calculi of extra- and intrahepatic bile ducts].
abstract: Endoscopy, extracorporeal shockwave lithotripsy (ESWL) and local lysis with alkaline solution of EDTA and bile salts in water were applied in combination in four patients with extra- and intrahepatic pigment stones as well as calcium bilirubinate covered concrements of the biliary tract. In the first patient (a man aged 80 years) a giant concrement of the bile duct was broken up after ESWL by three weeks of local chemical lysis and the fragments were removed by endoscopy. In the second case (man, aged 72), a nonextractable pigment stone was at first reduced in size by four-day local lysis and then removed endoscopically. Intrahepatic pigment stones were completely removed in the other two patients (boy of 12, man of 62) by local lysis only in 3 and 15 weeks, respectively. Even long-term use of the alkaline solution may not cause any serious side effects. Breaking up of stones after size reduction with ESWL of giant stones, size reduction of intact stones and contact lysis of intrahepatic stones are three important indications for chemical dissolution of biliary tract stones, respectively.
authors.affiliation: Abteilung für Gastroenterologie, Universität Frankfurt/Main.
authors.forename: S
authors.initials: S
authors.lastname: Güldütuna
authors.forename: A
authors.initials: A
authors.lastname: Hellstern
authors.forename: M
authors.initials: M
authors.lastname: Leuschner
authors.forename: W
authors.initials: W
authors.lastname: Kurtz
authors.forename: B
authors.initials: B
authors.lastname: Lembcke
authors.forename: K
authors.initials: K
authors.lastname: Heller
authors.forename: U
authors.initials: U
authors.lastname: Leuschner
mesh_terms: D000293:Adolescent; D000368:Aged; D000369:Aged, 80 and over; D001647:Bile Acids and Salts / Q000008:administration & dosage*; D001649:Bile Duct Diseases / Q000628:therapy; D001653:Bile Ducts, Intrahepatic; D002769:Cholelithiasis / Q000628:therapy*; D004492:Edetic Acid / Q000008:administration & dosage*; D004724:Endoscopy; D005069:Evaluation Studies as Topic; D042882:Gallstones / Q000628:therapy; D006801:Humans; D008096:Lithotripsy; D008297:Male; D008875:Middle Aged
chemical_list: D001647:Bile Acids and Salts; D004492:Edetic Acid
vernacular_title: Endoskopie, Stosswellenlithotripsie und lokale Lyse bei komplizierten Pigmentsteinen der extra- und intrahepatischen Gallengänge.