title: An unusual presentation of systemic lupus erythematosus.
abstract: A case of right hemiparesis in a 22-year-old, caucasian male is presented. Echocardiography and an indirect left ventriculogram revealed a mass in the left ventricle which was eventually removed at surgery. Histology of the ventricular wall revealed thrombus superimposed on a full thickness myocardial infarction with florid intimal proliferation of small arteries. This histological picture suggested a diagnosis of systemic lupus erythematosus. Serum immunology revealed raised antibody titres in keeping with systemic lupus erythematosus. This is an unusual presentation where the only manifestation of disease was hemiparesis secondary to an embolic episode, from thrombus in the left ventricle subsequent to a small localised myocardial infarct.
authors.affiliation: Department of Cardiothoracic Surgery, London Chest Hospital, UK.
authors.forename: R
authors.initials: R
authors.lastname: Uppal
authors.forename: M N
authors.initials: MN
authors.lastname: Sheppard
authors.forename: P
authors.initials: P
authors.lastname: Magee
mesh_terms: D000328:Adult; D006331:Heart Diseases / Q000150:complications* / Q000209:etiology; D006352:Heart Ventricles; D006429:Hemiplegia / Q000209:etiology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008297:Male; D009203:Myocardial Infarction / Q000150:complications / Q000209:etiology; D013927:Thrombosis / Q000150:complications* / Q000209:etiology