[Chromosomal polymorphism in patients with otospongiosis].
Cytogenetic examinations were performed on 18 patients with surgically verified otosclerosis. In comparison with 15 healthy patients satellites in the somatic chromosomes of D and G groups were found to occur significantly more frequently (p less than 0.005). Moreover, among the patients a case of 45,X karyotype with clinically incomplete Turner syndrome has been disclosed. The results obtained seem to support genetic hypothesis of otospongiosis pathogenesis.
Buczyłko
K
K
Kliniki Otolaryngologicznej Instytutu Chirurgii WAM Lódź.
Bratkowska
W
W
D004276:DNA, Satellite / Q000032:analysis*; D006801:Humans; D007621:Karyotyping; D010040:Otosclerosis / Q000235:genetics*; D011110:Polymorphism, Genetic / Q000235:genetics*
D004276:DNA, Satellite
Polimorfizm chromosomów u chorych na otospongioze.