Multiple miliary osteoma cutis.
We describe the clinical, radiographic, histologic, and metabolic features of an unusual case of multiple miliary osteoma cutis in an otherwise healthy 57-year-old woman. Although the pathogenesis of this rarely reported entity is not fully understood, the novel application of a dynamic bone study revealed a high rate of internal bone remodeling within the lesion. This finding prompted a brief therapeutic trial of a diphosphonate, not previously reported in the treatment of this condition.
Goldminz
D
D
Department of Dermatology, Yale University School of Medicine, New Haven, Connecticut.
Greenberg
R D
RD
D001842:Bone and Bones / Q000473:pathology; D002113:Calcification, Physiologic; D003707:Demeclocycline; D005260:Female; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000737:chemistry / Q000473:pathology*; D010016:Osteoma / Q000737:chemistry / Q000473:pathology*; D010118:Oxytetracycline; D012878:Skin Neoplasms / Q000737:chemistry / Q000473:pathology*
D003707:Demeclocycline; D010118:Oxytetracycline