title: Calcium phosphate cements: effect of fluorides on the setting and hardening of beta-tricalcium phosphate-dicalcium phosphate-calcite cements.
abstract: Increasing amounts of fluoride ions have been found to increase the setting and hardening rates of beta-tricalcium phosphate-dicalcium phosphate dihydrate-calcite cements. Thus, fluoride-containing cements reached a diametral strength of about 1.5 MPa after 15 d, but the fluoride-free reference sample reached only 0.45 MPa. The acceleration of setting and hardening is correlated to an increased rate of hydroxyapatite formation in the cement at the expense of dicalcium phosphate dihydrate and calcite. Adding monocalcium phosphate monohydrate and fluoride to the blends resulted in a marked decrease of their setting time from about 1 h down to 8 min, without greatly affecting their final strength.
authors.affiliation: Unité de Chimie des Interfaces, Université Catholique de Louvain, Louvain-la-Neuve, Belgium.
authors.forename: A A
authors.initials: AA
authors.lastname: Mirtchi
authors.forename: J
authors.initials: J
authors.lastname: Lemaître
authors.forename: E
authors.initials: E
authors.lastname: Munting
mesh_terms: D001031:Apatites / Q000737:chemistry; D001672:Biocompatible Materials; D001843:Bone Cements / Q000737:chemistry*; D002119:Calcium Carbonate / Q000737:chemistry; D002130:Calcium Phosphates / Q000737:chemistry*; D005459:Fluorides / Q000737:chemistry*; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning
chemical_list: D001031:Apatites; D001672:Biocompatible Materials; D001843:Bone Cements; D002130:Calcium Phosphates; C485828:alpha-tricalcium phosphate; C485817:beta-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; C020243:calcium phosphate; D002119:Calcium Carbonate; C018392:tricalcium phosphate; C485829:calcium phosphate, dibasic, anhydrous; D005459:Fluorides