title: Perspectives in colorectal cancer.
abstract: This paper presents an overview of recent developments pertaining to colorectal adenocarcinoma. It is aimed toward the practicing clinician. Topics discussed include epidemiologic observations; genetic predispositions; molecular biology findings; screening and early detection programs; endoscopy; principles of surgical resection; laser and radioimmunoguided surgery; staging; selection of patients for adjuvant chemotherapy; and considerations regarding biologic response modifiers and pain control in the advanced-disease setting.
authors.affiliation: Division of Surgical Oncology, Medical Center of Delaware, Wilmington.
authors.forename: L
authors.initials: L
authors.lastname: Herrera
authors.forename: P
authors.initials: P
authors.lastname: Luna
authors.forename: J R
authors.initials: JR
authors.lastname: Villarreal
authors.forename: M
authors.initials: M
authors.lastname: Brown
authors.forename: J
authors.initials: J
authors.lastname: Sorrentino
authors.forename: Y
authors.initials: Y
authors.lastname: Khalek
mesh_terms: D000230:Adenocarcinoma; D014408:Biomarkers, Tumor; D015179:Colorectal Neoplasms; D003131:Combined Modality Therapy; D016147:Genes, Tumor Suppressor; D006801:Humans; D008403:Mass Screening; D009367:Neoplasm Staging; D009857:Oncogenes
chemical_list: D014408:Biomarkers, Tumor