[Arterial infusion chemotherapy combined with biochemical modulation in cancer patients].
Both arterial infusion chemotherapy and biochemical modulation are effective for unresectable and recurrent cancer patients. Thus, we tried to combine these methods and studied their combined efficacy in 30 cancer patients. Overall effectiveness was 40% with this method. The efficacy of each regimen, such as beta-MF and CF, was approximately 36.4% and 66.7%, respectively. The effectiveness of cannulation into the proper hepatic artery and aorta was 48.6% and 16.7%, respectively. In this study, there were no serial or severe side effects. These findings suggested that arterial infusion chemotherapy in combination with biochemical modulation was a safe and effective method for treating cancer patients.
Suga
T
T
Dept. of Surgery, Cancer Research Institute, Kanazawa University.
Takahashi
Y
Y
Ogino
T
T
Mai
M
M
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D002945:Cisplatin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use*; D007261:Infusions, Intra-Arterial; D007370:Interferon Type I / Q000008:administration & dosage; D002955:Leucovorin / Q000008:administration & dosage; D008727:Methotrexate / Q000008:administration & dosage; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage; D009369:Neoplasms / Q000628:therapy*
D007155:Immunologic Factors; D007370:Interferon Type I; D008937:Mitomycins; D016685:Mitomycin; D002945:Cisplatin; D002955:Leucovorin; D005472:Fluorouracil; D008727:Methotrexate