[Cardiac diseases related to free radicals and active species of oxygen. Biochemistry (1)].
In the first part of this paper, a group of definitions are explained in order to understand the mechanisms groups of the most important enzymes which participate in the formations of free radicals and active species of oxygen in the heart. Furthermore, we focus on chemistry and the production of these different active species of oxygen, rounding of by giving information related to the importance of hypoxia-reoxygenation, as well as the lipidic peroxidation in the formation of oxygen free radicals. All this information provides us with a biochemical baseline to write a second part about the cardiovascular pathology related to the lack of equilibrium between pro-oxidation and anti-oxidation.
Romero Alvira
D
D
Hospital de Insalud, Calatayud, Zaragoza.
Villalba Martín
M P
MP
Bueno Gómez
J
J
D001669:Biochemical Phenomena; D001671:Biochemistry; D015687:Cell Hypoxia; D003327:Coronary Disease / Q000209:etiology*; D005609:Free Radicals / Q000378:metabolism; D006801:Humans; D015227:Lipid Peroxidation; D009206:Myocardium / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism*
D005609:Free Radicals; D010100:Oxygen
Enfermedades cardíacas relacionadas con los radicales libres y las especies activas del oxígeno. Bioquímica (1a. parte).