title: Hepatitis C virus infection is the major cause of severe liver disease in India.
abstract: The present study describes the status of hepatitis C virus infection in 167 patients with severe forms of liver diseases in India. The anti-HCV positivity rate was recorded as 43%, 47%, and 42% in patients with FHF, SAHF, and CAH respectively. HBV and HCV coinfection was recorded in 28% of FHF, 43% of SAHF and 75% of the CAH cases. Superinfection of HCV in HBsAg carriers was recorded in the 54% cases of FHF, 60% of SAHF and 42% of the CAH. None of these 167 patients was positive of HAV-IgM. Further, 27.7% of FHF, 26.4% of SAHF and 15.2% of CAH cases were neither HBV nor HCV markers positive. These can be labelled as non-A, non-B and non-C infections.
authors.affiliation: Department of Gastroenterology, All-India Institute of Medical Sciences, New Delhi.
authors.forename: B N
authors.initials: BN
authors.lastname: Tandon
authors.forename: M
authors.initials: M
authors.lastname: Irshad
authors.forename: S K
authors.initials: SK
authors.lastname: Acharya
authors.forename: Y K
authors.initials: YK
authors.lastname: Joshi
mesh_terms: D006509:Hepatitis B / Q000150:complications; D006526:Hepatitis C / Q000150:complications / Q000453:epidemiology*; D006521:Hepatitis, Chronic / Q000382:microbiology; D006801:Humans; D007194:India / Q000453:epidemiology; D008107:Liver Diseases / Q000382:microbiology*; D015163:Superinfection / Q000453:epidemiology