Sulfur conjugates as putative pneumotoxic metabolites of the pyrrolizidine alkaloid, monocrotaline.
Huxtable
R J
RJ
Department of Pharmacology, College of Medicine, University of Arizona, Tucson 85724.
Bowers
R
R
Mattocks
A R
AR
Michnicka
M
M
D000818:Animals; D001711:Biotransformation; D003545:Cysteine / Q000031:analogs & derivatives / Q000378:metabolism / Q000633:toxicity; D005978:Glutathione / Q000378:metabolism / Q000633:toxicity; D008099:Liver / Q000378:metabolism; D008168:Lung / Q000187:drug effects*; D016686:Monocrotaline / Q000031:analogs & derivatives; D011763:Pyrrolizidine Alkaloids / Q000378:metabolism / Q000493:pharmacokinetics / Q000633:toxicity*; D051381:Rats
D011763:Pyrrolizidine Alkaloids; C069710:7-cysteinyldehydroretronecine; C064161:glutathione-dehydro-retronecine conjugate; D016686:Monocrotaline; D005978:Glutathione; D003545:Cysteine