Correlation of negative symptoms in schizophrenia with frontal lobe parameters on magnetic resonance imaging.
Among 24 chronic schizophrenic patients, the 10 with high ratings for negative symptoms had significantly higher left-frontal: temporal-cortical T2 ratios. This finding was unrelated to age, dose of medication, length of illness or handedness. No T1 or T2 changes were found to be associated with positive symptoms or tardive dyskinesia in the regions examined.
Williamson
P
P
London Psychiatric Hospital.
Pelz
D
D
Merskey
H
H
Morrison
S
S
Conlon
P
P
D000328:Adult; D004409:Dyskinesia, Drug-Induced / Q000175:diagnosis / Q000473:pathology; D005260:Female; D005625:Frontal Lobe / Q000473:pathology*; D007839:Functional Laterality; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000175:diagnosis* / Q000473:pathology; D012565:Schizophrenic Psychology; D013702:Temporal Lobe / Q000473:pathology; D013997:Time Factors