Postoperative primary adrenal failure in a patient with anticardiolipin antibodies.
A 50-year-old woman with no history of thrombosis or recurrent abortions developed pulmonary thromboembolism and bilateral hemorrhagic adrenal infarction with adrenal failure after hysterectomy for uterine fibroids. Anticardiolipin antibodies (aCL) were detected in high titer and have persisted. She remains well, without further thromboses, taking steroid replacement and warfarin anticoagulation. The initial presentation of aCL related disease can be as thrombotic postoperative complications in middle-age.
Komesaroff
P A
PA
Ewen Downie Metabolic Unit, Alfred Hospital, Prahran, Victoria, Australia.
Yung
A P
AP
Topliss
D J
DJ
D000307:Adrenal Gland Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000276:immunology; D000311:Adrenal Glands / Q000098:blood supply; D000906:Antibodies / Q000032:analysis*; D001323:Autoantibodies / Q000032:analysis; D001779:Blood Coagulation Factors / Q000032:analysis / Q000276:immunology; D002308:Cardiolipins / Q000276:immunology*; D005260:Female; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D007044:Hysterectomy; D007238:Infarction / Q000209:etiology; D016682:Lupus Coagulation Inhibitor; D008875:Middle Aged; D011183:Postoperative Complications; D014057:Tomography, X-Ray Computed
D000906:Antibodies; D001323:Autoantibodies; D001779:Blood Coagulation Factors; D002308:Cardiolipins; D016682:Lupus Coagulation Inhibitor