Jejunal mucosal lactase activity from birth to three weeks in conventionally raised calves fed an electrolyte solution on days 5, 6 and 7 instead of milk.
The purpose of this study was to evaluate the effect of withdrawal of lactose from the diet for 72 hours on lactase activity in the jejunal mucosa of conventionally raised calves. The descending portion of the duodenum of six Holstein calves less than 24 hours old was cannulated. The calves were fed milk except on days 5, 6 and 7 when they were given the same volume of an electrolyte solution. Sequential biopsy specimens of the proximal jejunal mucosa were obtained for three weeks and the lactase activity determined. Lactase activity was highest on day 1 and a trend toward decreased lactase activity from birth until three weeks was observed. Mean lactase activity was significantly (p less than 0.05) higher for days 1, and 3 compared to days 9, 13 and 17. The withdrawal of milk and replacement by an electrolyte solution during three days had no significant effect on jejunal mucosal lactase activity in neonatal calves.
St Jean
G D
GD
Department of Surgery and Medicine, College of Veterinary Medicine, Kansas State University, Manhattan 66506-5606.
Schmall
L M
LM
Rings
D M
DM
Hoffsis
G F
GF
Hull
B L
BL
D000818:Animals; D000831:Animals, Newborn / Q000378:metabolism*; D002417:Cattle / Q000378:metabolism*; D004573:Electrolytes / Q000008:administration & dosage*; D007413:Intestinal Mucosa / Q000201:enzymology; D007583:Jejunum / Q000201:enzymology*; D043322:Lactase; D007785:Lactose / Q000008:administration & dosage; D008297:Male; D008892:Milk / Q000378:metabolism; D001616:beta-Galactosidase / Q000378:metabolism*
D004573:Electrolytes; D043322:Lactase; D001616:beta-Galactosidase; D007785:Lactose