[Cholinesterase activity and the rate of the maturation of the sensorimotor reflexes in the progeny of white rats administered carbophos during pregnancy].
Female mongrel albino rats were administered orally carbophos in a dose of 10 mg/kg (1/100 of LD50) on the 11th, 13th, 15th and 17th days of pregnancy. The antenatal administration of carbophos was shown to produce combined disturbances of the postnatal development of the mongrel albino rats manifesting themselves in changes of the maturation of sensomotor reflexes, cholinesterase activity, increased addiction both to carbophos and ethanol.
Ivashin
V M
VM
Chumakova
O V
OV
Bandazhevskiĭ
Iu I
IuI
Oboznyĭ
N D
ND
Zakharchenko
R G
RG
D000110:Acetylcholinesterase / Q000187:drug effects / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000201:enzymology; D002802:Cholinesterases / Q000097:blood / Q000187:drug effects*; D005260:Female; D008294:Malathion / Q000494:pharmacology*; D009043:Motor Activity / Q000187:drug effects*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D012018:Reflex / Q000187:drug effects*; D013997:Time Factors
D000110:Acetylcholinesterase; D002802:Cholinesterases; D008294:Malathion
Aktivnost' kholinésterazy i skorost' sozrevaniia sensorno-dvigatel'nykh refleksov u potomstva belykh krys pri vvedenii karbofosa v period beremennosti.