title: Acute sarcocystosis-like disease in a dog.
abstract: Two of 8 littermate Rottweiler dogs developed persistent diarrhea at 6.5 weeks of age. Dog 1 was euthanatized at 14 weeks of age and had hepatitis characterized by necrosis and mixed leukocyte infiltrations in association with a previously unrecognized Sarcocystis-like protozoon. The organism was free in the hepatocyte cytoplasm without a parasitophorous vacuole, had divided by schizogony, and stained with anti-Sarcocystis serum, but did not stain with anti-Toxoplasma gondii or anti-Neospora caninum serum in an immunohistochemical test. Dog 2 was euthanatized at 10 weeks of age. This dog had large necrotic, hemorrhagic mesenteric lymph nodes. Numerous T gondii tachyzoites were observed in association with these lesions. The organism divided by endodyogeny and stained specifically with anti-T gondii serum.
authors.affiliation: Livestock and Poultry Sciences Institute, USDA, Beltsville, MD 20705.
authors.forename: J P
authors.initials: JP
authors.lastname: Dubey
authors.forename: S F
authors.initials: SF
authors.lastname: Cosenza
authors.forename: T P
authors.initials: TP
authors.lastname: Lipscomb
authors.forename: M J
authors.initials: MJ
authors.lastname: Topper
authors.forename: C A
authors.initials: CA
authors.lastname: Speer
authors.forename: L D
authors.initials: LD
authors.lastname: Hoban
authors.forename: S W
authors.initials: SW
authors.lastname: Davis
authors.forename: A L
authors.initials: AL
authors.lastname: Kincaid
authors.forename: J C
authors.initials: JC
authors.lastname: Seely
authors.forename: G E
authors.initials: GE
authors.lastname: Marrs
mesh_terms: D000208:Acute Disease; D000818:Animals; D004283:Dog Diseases / Q000469:parasitology* / Q000473:pathology; D004285:Dogs; D005260:Female; D008099:Liver / Q000469:parasitology / Q000473:pathology; D008198:Lymph Nodes / Q000469:parasitology / Q000473:pathology; D008297:Male; D012523:Sarcocystosis / Q000473:pathology / Q000662:veterinary*; D014124:Toxoplasmosis, Animal