Presacral extramedullary hematopoiesis in thalassemia intermedia.
Extramedullary hematopoiesis is manifested by several clinical hematologic disorders including beta-thalassemia major and thalassemia intermedia. We report an unusual case of extramedullary hematopoiesis, which presented as a painful presacral mass in a patient with beta-thalassemia intermedia. The diagnosis was confirmed by a needle biopsy guided by computed tomography. The patient responded well to radiation therapy to the sacral region.
Sproat
I A
IA
Department of Radiology, McMaster University Medical Centre, Hamilton, Ont.
Dobranowski
J
J
Chen
V
V
Ali
M
M
Woods
D
D
D000328:Adult; D001707:Biopsy, Needle / Q000379:methods; D005260:Female; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D008297:Male; D008875:Middle Aged; D013131:Spine / Q000000981:diagnostic imaging / Q000502:physiology; D013789:Thalassemia / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology*; D014057:Tomography, X-Ray Computed