Identity between polysaccharide antigens of Moraxella nonliquefaciens, group B Neisseria meningitidis, and Escherichia coli K1 (non-O acetylated).
A surface polysaccharide antigen of Moraxella nonliquefaciens, reported to be cross-reactive with the capsular polysaccharides of group B Neisseria meningitidis and Escherichia coli K1 (K. Błvre, K. Bryn, O. Closs, N. Hagen, and L. O. Froholm, NIPH Ann. 6:65-73, 1983), was isolated, purified, and characterized chemically, immunologically, and by nuclear magnetic resonance. This polysaccharide was shown to be a linear homopolymer of alpha (2----8)-linked N-acetylneuraminic acid, identical to the capsular polysaccharide of group B N. meningitidis and O-acetyl-negative variants of E. coli K1.
Devi
S J
SJ
Laboratory of Developmental and Molecular Immunity, National Institute of Child Health and Human Development, Bethesda, Maryland 20892.
Schneerson
R
R
Egan
W
W
Vann
W F
WF
Robbins
J B
JB
Shiloach
J
J
D000818:Animals; D000942:Antigens, Bacterial / Q000032:analysis* / Q000276:immunology; D004926:Escherichia coli / Q000276:immunology*; D005260:Female; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D009016:Moraxella / Q000276:immunology*; D019158:N-Acetylneuraminic Acid; D009345:Neisseria meningitidis / Q000276:immunology*; D011135:Polysaccharides, Bacterial / Q000032:analysis* / Q000276:immunology; D012794:Sialic Acids / Q000032:analysis
D000942:Antigens, Bacterial; D011135:Polysaccharides, Bacterial; D012794:Sialic Acids; D019158:N-Acetylneuraminic Acid