title: Concentrations of fumonisin B1 in feeds associated with animal health problems.
abstract: Ninety-eight samples of feeds associated with 44 cases of equine leukoencephalomalacia (ELEM) and 83 samples of feed associated with 42 cases of a porcine pulmonary edema syndrome (PPE) were analyzed for fumonisin B1 (FB1). For comparison purposes, 51 feed samples not associated with PPE or ELEM were also analyzed. Feed associated with ELEM contained FB1 ranging from less than 1 microgram/g to 126 micrograms/g with 75% of the cases having at least 1 sample above 10 micrograms/g. Feeds associated with PPE ranged from less than 1 microgram/g to 330 micrograms/g with 71% of the cases having at least 1 sample greater than 10 micrograms/g. Quantitation was by high performance liquid chromatography (HPLC)/fluorescence using the fluorescamine derivative with confirmation by thin layer chromatography (TLC) and/or gas chromatography/mass spectroscopy (GC/MS).
authors.affiliation: US Department of Agriculture, Animal and Plant Health Inspection Service, National Veterinary Services Laboratories, Ames, IA 50010.
authors.forename: P F
authors.initials: PF
authors.lastname: Ross
authors.forename: L G
authors.initials: LG
authors.lastname: Rice
authors.forename: R D
authors.initials: RD
authors.lastname: Plattner
authors.forename: G D
authors.initials: GD
authors.lastname: Osweiler
authors.forename: T M
authors.initials: TM
authors.lastname: Wilson
authors.forename: D L
authors.initials: DL
authors.lastname: Owens
authors.forename: H A
authors.initials: HA
authors.lastname: Nelson
authors.forename: J L
authors.initials: JL
authors.lastname: Richard
mesh_terms: D000821:Animal Feed / Q000009:adverse effects / Q000032:analysis*; D000818:Animals; D002274:Carcinogens, Environmental / Q000009:adverse effects / Q000032:analysis; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D004678:Encephalomalacia / Q000209:etiology / Q000662:veterinary; D005516:Food Microbiology; D037341:Fumonisins; D008401:Gas Chromatography-Mass Spectrometry; D006734:Horse Diseases / Q000209:etiology*; D006736:Horses; D009183:Mycotoxins / Q000009:adverse effects / Q000032:analysis*; D011654:Pulmonary Edema / Q000209:etiology / Q000662:veterinary; D013552:Swine; D013553:Swine Diseases / Q000209:etiology*; D003313:Zea mays
chemical_list: D002274:Carcinogens, Environmental; D037341:Fumonisins; D009183:Mycotoxins; C056933:fumonisin B1