title: [The granulocyte-macrophage colony stimulating factor and the radiation protective effect of yeast mannan].
abstract: The effect of mannan polysaccharide on the haemopoiesis recovery in irradiated mice has been investigated. Mannan has been shown to exert both the protective and the stimulatory effect: it accelerates restoration of femur bone marrow cellularity and nucleate cell number in the peripheral blood and causes a larger initial yield and subsequent more rapid postirradiation dynamics of pluripotent haemopoietic stem cells and precursor cells of granulocytes and macrophages.
authors.forename: N M
authors.initials: NM
authors.lastname: Chernysheva
authors.forename: V P
authors.initials: VP
authors.lastname: Kaplan
authors.forename: A G
authors.initials: AG
authors.lastname: Konopliannikov
authors.forename: T L
authors.initials: TL
authors.lastname: Babaian
authors.forename: L A
authors.initials: LA
authors.lastname: Lepekhina
mesh_terms: D000818:Animals; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000502:physiology*; D006410:Hematopoiesis / Q000187:drug effects*; D008297:Male; D008351:Mannans / Q000627:therapeutic use*; D051379:Mice; D008808:Mice, Inbred CBA; D011837:Radiation-Protective Agents / Q000627:therapeutic use*; D013268:Stimulation, Chemical
chemical_list: D008351:Mannans; D011837:Radiation-Protective Agents; D016178:Granulocyte-Macrophage Colony-Stimulating Factor
vernacular_title: Stimuliruiushchiĭ granulotsitarno-makrofagal'nyĭ rostok i radiozashchitnyĭ éffekty drozhzhevogo mannana.