title: Oxygenation in the stomach and the effect of truncal vagotomy.
abstract: A Clark polarographic oxygen electrode allowed detailed mapping of tissue oxygen (PtO2) levels on the anterior surface of the stomach in five patients undergoing cholecystectomy. No significant difference in mean PtO2 was detectable between greater and lesser curvatures. A significant difference in mean PtO2 was detected between the body of the stomach and the pylorus (Mann-Whitney, P less than 0.01). The effect of truncal vagotomy on PtO2 was evaluated in six patients undergoing this procedure for duodenal ulceration. Mean postvagotomy stomach PtO2 levels (46 +/- 12 mmHg) were significantly lower (Wilcoxon test, P less than 0.001) than prevagotomy levels (59 +/- 14 mmHg). Truncal vagotomy did not have any significant effect on small intestinal PtO2. This work provides the first objective evidence of the relatively diminished tissue oxygenation in the gastric antrum and pyloric region, and confirms blood flow studies of the effects of vagotomy.
authors.affiliation: Department of Surgery, University of Wales College of Medicine, Heath Park, Cardiff, UK.
authors.forename: W G
authors.initials: WG
authors.lastname: Sheridan
authors.forename: R H
authors.initials: RH
authors.lastname: Lowndes
authors.forename: M H
authors.initials: MH
authors.lastname: Lewis
authors.forename: H L
authors.initials: HL
authors.lastname: Young
mesh_terms: D000328:Adult; D004381:Duodenal Ulcer / Q000601:surgery; D006801:Humans; D007421:Intestine, Small / Q000737:chemistry; D008875:Middle Aged; D010100:Oxygen / Q000032:analysis*; D012039:Regional Blood Flow; D013270:Stomach / Q000098:blood supply / Q000737:chemistry*; D015167:Vagotomy, Truncal
chemical_list: D010100:Oxygen