[Study of the structure of anthracycline antibiotics by ERIAD mass spectrometry].
Fragmentation of antibiotics daunorubicin, carminomycin, doxorubicin and their semisynthetic analogues under conditions of the new mass spectrometry method ERIAD is discussed. Signals of protonated molecular ion (M + H)+ and ions of fragments are present in all the mass spectra. The results are compared with literary data obtained by means of other (EI and FAB MS) mass spectrometry methods.
Mirgorodskaia
O A
OA
Olsuf'eva
E N
EN
Matveeva
E R
ER
Podmelezhnikov
A V
AV
D000903:Antibiotics, Antineoplastic / Q000737:chemistry*; D002360:Carubicin / Q000031:analogs & derivatives / Q000737:chemistry; D003630:Daunorubicin / Q000031:analogs & derivatives / Q000737:chemistry; D004317:Doxorubicin / Q000031:analogs & derivatives / Q000737:chemistry; D013058:Mass Spectrometry / Q000379:methods*; D015394:Molecular Structure
D000903:Antibiotics, Antineoplastic; D004317:Doxorubicin; D002360:Carubicin; D003630:Daunorubicin
Izuchenie stroeniia antratsiklinovykh antibiotikov metodom ERIAD mass- spektrometrii.