[Physiopathologic mechanisms of photo-induced cutaneous alterations].
Ultraviolet rays are responsible for changes in the skin and in particular for actinic ageing. The harmful role of free radicals is now well established in this field. Defense against radicals is provided by enzymatic systems and by non-enzymatic scavenger systems. Some drugs protect against radicals and this property is utilized in photo-induced dermatoses.
Thomas
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Service de Dermatologie, Hôpital Claude-Huriez, CHU, Lille.
D002374:Catalase / Q000502:physiology; D004548:Elasticity; D016166:Free Radical Scavengers; D005609:Free Radicals; D005979:Glutathione Peroxidase / Q000502:physiology; D006801:Humans; D015227:Lipid Peroxidation; D010858:Pigmentation; D015595:Skin Aging / Q000187:drug effects / Q000502:physiology*; D013482:Superoxide Dismutase / Q000502:physiology; D014466:Ultraviolet Rays / Q000009:adverse effects*
D016166:Free Radical Scavengers; D005609:Free Radicals; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase
Mécanismes physiopathologiques des altérations cutanées photo-induites.