Delayed recovery from lithium neurotoxicity.
Recovery from lithium-induced neurotoxicity can take much longer than the 2 to 3 weeks previously reported. Contributing factors could include advanced age and underlying clinical or subclinical brain disease. However, the occurrence of lithium-induced neurotoxicity does not preclude reinstitution of lithium treatment. We report three case histories that illustrate these points.
Nambudiri
D E
DE
Division of Geriatric Services, New York Hospital-Cornell Medical Center, White Plains.
Meyers
B S
BS
Young
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RC
D000368:Aged; D000369:Aged, 80 and over; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D004569:Electroencephalography / Q000187:drug effects; D005260:Female; D006801:Humans; D008094:Lithium / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D016651:Lithium Carbonate; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011605:Psychoses, Substance-Induced / Q000097:blood / Q000175:diagnosis* / Q000523:psychology
D016651:Lithium Carbonate; D008094:Lithium