Eosinophilic cellulitis: histologic features in a cutaneous mastocytoma.
A cutaneous mastocytoma with associated histologic features of eosinophilic cellulitis is reported. The tumor occurred as a small, asymptomatic lesion on the left thigh of a 4-year-old boy. Microscopically, an accumulation of mast cells, microgranulomas, eosinophils and 'flame figures' was present. A pathogenesis involving mast cell degranulation, eosinophil chemotactic factors and eosinophil major basic protein is discussed.
Hunt
S J
SJ
Cutaneous Pathology, St. John's Mercy Medical Center, St. Louis, Mo.
Santa Cruz
D J
DJ
D002481:Cellulitis / Q000150:complications / Q000473:pathology*; D002675:Child, Preschool; D004802:Eosinophilia / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D012515:Mast-Cell Sarcoma / Q000150:complications / Q000473:pathology*; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology*