title: Xenon-enhanced CT of the brain: effect of flow activation on derived cerebral blood flow measurements.
abstract: The errors associated with derivation of cerebral blood flow values by the xenon-enhanced CT method have been evaluated through computer simulations as a function of flow-activation patterns and different scanning protocols. The results of this study indicate that actual flow activation during inhalation increases the derived flow values in a systematic way. Compared with the errors introduced by CT noise and/or variations in scanning protocols, flow activation introduces relatively small errors in the derived flow value when the washin technique is used.
authors.affiliation: Department of Diagnostic Radiology, University of Pittsburgh, PA 15261.
authors.forename: W F
authors.initials: WF
authors.lastname: Good
authors.forename: D
authors.initials: D
authors.lastname: Gur
mesh_terms: D000280:Administration, Inhalation; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D003198:Computer Simulation; D006801:Humans; D013268:Stimulation, Chemical; D014057:Tomography, X-Ray Computed; D014978:Xenon / Q000008:administration & dosage
chemical_list: D014978:Xenon