[Combined action of anti-arrhythmia agents].
A significant potentiation of antiarrhythmic effect was observed in 121 dogs with arrhythmias 24 and 48 hours after the coronary artery ligation when the following drugs were combined: N-propylajmaline bromide (1A class) and trimecaine (1B class), quinidine (1A class) and trimecaine, N-propylajmaline bromide and anaprilin (2 class). The potentiation is attributed to the different molecular mechanisms of action of the drugs.
Gendenshteĭn
E I
EI
Kostin
Ia V
IaV
Balashov
V P
VP
Oleĭnikov
V E
VE
D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000494:pharmacology*; D001145:Arrhythmias, Cardiac / Q000188:drug therapy*; D004285:Dogs; D004359:Drug Therapy, Combination; D011219:Prajmaline / Q000008:administration & dosage / Q000494:pharmacology; D011433:Propranolol / Q000008:administration & dosage / Q000494:pharmacology; D011802:Quinidine / Q000008:administration & dosage / Q000494:pharmacology; D014288:Trimecaine / Q000008:administration & dosage / Q000494:pharmacology; D014700:Verapamil / Q000008:administration & dosage / Q000494:pharmacology
D000889:Anti-Arrhythmia Agents; D011219:Prajmaline; D011433:Propranolol; D014700:Verapamil; D014288:Trimecaine; D011802:Quinidine
Sochetannoe kombinirovannoe deĭstvie antiaritmicheskikh sredstv.