title: [The role of oxygen-binding properties of hemoglobin in the development of oxygen deficiency in acute exogenous hyperthermia].
abstract: Acid-base balance and oxygen-binding hemoglobin properties in mixed venous blood have been studied in 25 mongrel rabbits with acute environmental hyperthermia. As oxygen-hemoglobin affinity at standard pH, pCO2 and temperature increases, the effect of heat on oxygen-hemoglobin interaction is considerably attenuated. The Bohr effect increases. The mechanisms of changes in oxygen-binding properties of hemoglobin and their role in development of oxygen deficiency are discussed.
authors.forename: V V
authors.initials: VV
authors.lastname: Zinchuk
authors.forename: M V
authors.initials: MV
authors.lastname: Borisiuk
mesh_terms: D000136:Acid-Base Equilibrium / Q000502:physiology; D000818:Animals; D004195:Disease Models, Animal; D006358:Hot Temperature; D006863:Hydrogen-Ion Concentration; D000860:Hypoxia / Q000209:etiology*; D010100:Oxygen / Q000097:blood*; D010108:Oxyhemoglobins / Q000378:metabolism*; D011817:Rabbits
chemical_list: D010108:Oxyhemoglobins; D010100:Oxygen
vernacular_title: Rol' kislorodsviazuiushchikh svoĭstv gemoglobina v geneze kislorodnoĭ nedostatochnosti pri ostroĭ ékzogennoĭ gipertermii.