title: Squamous cell carcinoma of the upper aerodigestive tract associated with well-differentiated carcinoma of the thyroid gland.
abstract: The association of squamous cell carcinoma of the upper aerodigestive tract with well-differentiated thyroid carcinomas has rarely been reported in the literature. We report 10 cases illustrating this occurrence. In eight cases, the thyroid carcinoma was discovered accidentally on histological examination of a single neck node, a neck node dissection specimen, an unexpectedly found thyroid nodule, or a systematically resected thyroid lobe, all during surgical treatment of an upper aerodigestive tract carcinoma. In the other two cases, metastatic thyroid neck nodes appeared during the follow-up of a patient with an upper aerodigestive tract carcinoma. No case of upper aerodigestive tract carcinomas was found during the follow-up of thyroid cancer patients. In most cases, adequate thyroid cancer surgery was performed simultaneously or later. Prognosis was essentially determined by the upper aerodigestive tract cancer.
authors.affiliation: Department of Head and Neck Surgery, Institute Gustave-Roussy, Villejuif, France.
authors.forename: L
authors.initials: L
authors.lastname: Pacheco-Ojeda
authors.forename: C
authors.initials: C
authors.lastname: Micheau
authors.forename: B
authors.initials: B
authors.lastname: Luboinski
authors.forename: J
authors.initials: J
authors.lastname: Richard
authors.forename: J P
authors.initials: JP
authors.lastname: Travagli
authors.forename: G
authors.initials: G
authors.lastname: Schwaab
authors.forename: P
authors.initials: P
authors.lastname: Marandas
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000628:therapy; D003131:Combined Modality Therapy; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000628:therapy; D006801:Humans; D008207:Lymphatic Metastasis; D009378:Neoplasms, Multiple Primary / Q000473:pathology / Q000628:therapy; D011379:Prognosis; D013964:Thyroid Neoplasms / Q000473:pathology / Q000601:surgery