title: [Biological activity of gamma-irradiated serum albumin].
abstract: Gamma-irradiated serum albumin activated L-tyrosine oxidation to 3,4-dioxyphenyl alanine (DOPA) and forms adducts with DOPA oxidation products. These adducts are more resistant to proteolysis and have bactericidal and mutagenic capacity. A possible role of such adducts in a radiation damage to the organism is discussed.
authors.forename: V A
authors.initials: VA
authors.lastname: Kopylov
authors.forename: A F
authors.initials: AF
authors.lastname: Revin
authors.forename: S S
authors.initials: SS
authors.lastname: Iurov
authors.forename: N V
authors.initials: NV
authors.lastname: Shchelkaeva
authors.forename: A M
authors.initials: AM
authors.lastname: Kuzin
mesh_terms: D004295:Dihydroxyphenylalanine / Q000378:metabolism; D004347:Drug Interactions; D005720:Gamma Rays; D066298:In Vitro Techniques; D010084:Oxidation-Reduction / Q000528:radiation effects; D011485:Protein Binding / Q000528:radiation effects; D012710:Serum Albumin, Bovine / Q000378:metabolism / Q000528:radiation effects*; D012996:Solutions; D014443:Tyrosine / Q000378:metabolism
chemical_list: D012996:Solutions; D012710:Serum Albumin, Bovine; D014443:Tyrosine; D004295:Dihydroxyphenylalanine
vernacular_title: Biologicheskaia aktivnost' gamma-obluchennogo syvorotochnogo al'bumina.