Exaggerated prolactin response to thyrotropin-releasing hormone in infertile women with the luteinized unruptured follicle syndrome.
Ten cases of luteinized unruptured follicle (LUF) syndrome out of 250 women with unexplained infertility were detected on ultrasonography, giving a frequency of 4%. Hormonal analysis revealed lower serum progesterone levels at mid-luteal phase in LUF cases, suggesting a link between LUF syndrome and inadequate luteal phase. Prolactin response to thyrotropin-releasing hormone was exaggerated in LUF cases as compared with ovulatory cases. Aberrant prolactin release may be a contributory factor in the pathophysiology of the LUF syndrome.
Kugu
K
K
Department of Obstetrics and Gynecology, Faculty of Medicine, University of Tokyo, Japan.
Taketani
Y
Y
Kohda
K
K
Mizuno
M
M
D000858:Anovulation / Q000097:blood* / Q000523:psychology; D003338:Corpus Luteum / Q000503:physiopathology*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007247:Infertility, Female / Q000097:blood* / Q000523:psychology; D007986:Luteinizing Hormone / Q000097:blood; D006080:Ovarian Follicle / Q000503:physiopathology*; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood*; D013315:Stress, Psychological / Q000150:complications; D013577:Syndrome; D013973:Thyrotropin-Releasing Hormone
D011374:Progesterone; D013973:Thyrotropin-Releasing Hormone; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone