Acute changes of serum markers for tissue damage after ESWL of kidney stones.
Seventeen serum markers (including 9 enzyme activities) for eventual tissue damage were studied after ESWL in 40 patients with unilateral kidney calculosis. No changes were established in the 8 non-enzymic parameters and the activities of amylase, lipase, AST (GOT), ALT (GPT) and CK-MB. A statistically significant increase was found in LDH, alpha-HBDH, CK (twice) and glutamate dehydrogenase (3 times). The slight elevation of LDH and alpha-HBDH could be due to haemolysis caused by the shock waves. Increased activity of CK suggested myolysis and that of GlDH a hepatocellular damage.
Apostolov
I
I
Department of Clinical Laboratory, Emergency Medical Institute, N. I. Pirogov, Sofia, Bulgaria.
Minkov
N
N
Koycheva
M
M
Isterkov
M
M
Abadjyev
M
M
Ondeva
V
V
Trendafilova
T
T
D000328:Adult; D015415:Biomarkers / Q000097:blood*; D004798:Enzymes / Q000097:blood*; D005260:Female; D006461:Hemolysis; D006801:Humans; D007668:Kidney / Q000293:injuries; D007669:Kidney Calculi / Q000628:therapy*; D008096:Lithotripsy / Q000009:adverse effects*; D008099:Liver / Q000293:injuries; D008297:Male; D009132:Muscles / Q000293:injuries; D010179:Pancreas / Q000293:injuries
D015415:Biomarkers; D004798:Enzymes