[Role of age at the moment of irradiation on the induction of tumors].
The probability that rats develop tumours following a 3 Gy exposure to gamma rays from cobalt 60 was observed to depend on age at exposure. Lifetime excess of neoplasia decreased by a factor of about 10 in 9-month-old rats as compared to animals irradiated in utero. The 3-month age group developed slightly fewer tumours than the group irradiated in utero, and tumour location was different. The higher incidence of tumours observed in the foetal group was mainly due to the high sensitivities of central nervous system and gonads during organogenesis.
Morin
M
M
Masse
R
R
Lafuma
J
J
D000310:Adrenal Gland Neoplasms / Q000453:epidemiology; D000367:Age Factors; D000818:Animals; D001932:Brain Neoplasms / Q000453:epidemiology; D004307:Dose-Response Relationship, Radiation; D005260:Female; D008297:Male; D009374:Neoplasms, Experimental / Q000453:epidemiology* / Q000209:etiology; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology*; D010911:Pituitary Neoplasms / Q000453:epidemiology; D051381:Rats; D011919:Rats, Inbred Strains; D013964:Thyroid Neoplasms / Q000453:epidemiology
Rôle de l'âge au moment de l'irradiation sur l'induction des tumeurs.