title: Chronic leg ulcers in sickle cell disease: experience in Ibadan, Nigeria.
abstract: The prevalence of chronic leg ulcers was investigated in 872 adults with sickle cell disease (SCD) (630 HbSS and 242 HbSC) at Ibadan, Nigeria. The incidence was 7.5% in HbSS and 1.7% in HbSC patients. The sex ratio in HbSS was 2:1 in favour of males, and three of the four HbSC were females. Ulcers were sited around the ankles in more than 70% of the patients. The duration of the ulcers varied from less than 1 year to more than 20 years. There was no bias for social class. Response to therapy, including autologous skin graft, was poor.
authors.affiliation: Department of Haematology, University College Hospital, Ibadan, Nigeria.
authors.forename: M A
authors.initials: MA
authors.lastname: Durosinmi
authors.forename: S M
authors.initials: SM
authors.lastname: Gevao
authors.forename: G J
authors.initials: GJ
authors.lastname: Esan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000755:Anemia, Sickle Cell / Q000150:complications*; D002648:Child; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007871:Leg Ulcer / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009549:Nigeria