Lens coenzymes and cataract formation.
The present work discusses the role of certain coenzymes in the metabolic and the biophysical processes maintaining the nativity of lens components. It also analyses results of the levels of oxidized and reduced forms of nicotine amide coenzymes and glutathione in the lens folling insults by both physical and chemical cataractogenic agents. The role of flavine and flavine coenzymes in the maintainance of the biochemical and biophysical stability of the lens has also been discussed. Data concerning the enzymatic biosynthesis and degradation of the lens coenzymes has been presented.
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Biochemical Laboratory Odessa Academician Filatov Research Institute of Eye Diseases and Tissue Therapy, USSR.
D000818:Animals; D002386:Cataract / Q000201:enzymology*; D003067:Coenzymes / Q000378:metabolism*; D005182:Flavin-Adenine Dinucleotide / Q000378:metabolism; D005978:Glutathione / Q000378:metabolism; D007908:Lens, Crystalline / Q000201:enzymology*; D012256:Riboflavin / Q000008:administration & dosage
D003067:Coenzymes; D005182:Flavin-Adenine Dinucleotide; D005978:Glutathione; D012256:Riboflavin