Meningococcal disease in the United States--1986. Meningococcal Disease Study Group.
Active surveillance for invasive meningococcal disease was conducted during 1986 and 1987 in six areas of the United States with a total population of approximately 34 million persons. The incidence of meningococcal disease was 1.3:10(5). The highest incidence of disease among the surveillance areas was in Los Angeles County (1.65:10(5). Neisseria meningitidis serogroups B and C caused about equal amounts of disease, which reflects a recent increase in the incidence of group C disease. Group C caused more than half of the cases of meningococcal disease in Los Angeles and Tennessee but less than one-third of the cases in Missouri and Oklahoma. Multilocus enzyme electrophoresis demonstrated that a group of closely related isolates of N. meningitidis was prevalent in Los Angeles during the surveillance period and was associated with an increased incidence of meningococcal disease there.
Pinner
R W
RW
Division of Bacterial and Mycotic Diseases, Center for Infectious Diseases, Centers for Disease Control, Atlanta, Georgia 30333.
Gellin
B G
BG
Bibb
W F
WF
Baker
C N
CN
Weaver
R
R
Hunter
S B
SB
Waterman
S H
SH
Mocca
L F
LF
Frasch
C E
CE
Broome
C V
CV
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D015141:Los Angeles / Q000453:epidemiology; D008589:Meningococcal Infections / Q000453:epidemiology*; D008875:Middle Aged; D008923:Missouri / Q000453:epidemiology; D009345:Neisseria meningitidis / Q000145:classification / Q000187:drug effects / Q000276:immunology; D009515:New Jersey / Q000453:epidemiology; D009825:Oklahoma / Q000453:epidemiology; D011159:Population Surveillance; D012621:Seasons; D012703:Serotyping; D013714:Tennessee / Q000453:epidemiology; D014481:United States / Q000453:epidemiology; D014861:Washington / Q000453:epidemiology
D000900:Anti-Bacterial Agents