title: Geographic and birth cohort associations of Kaposi's sarcoma among homosexual men in Canada.
abstract: The authors conducted an analysis of all 677 cases of Kaposi's sarcoma among the 3,047 cases of acquired immunodeficiency syndrome diagnosed in homosexual/bisexual men in Canada between 1980 and 1989. The proportion with Kaposi's sarcoma declined from 32.2% during 1980-1985 to 15.0% in 1989. The proportion with Kaposi's sarcoma was significantly higher in primary epidemic centers (Vancouver, Toronto, and Montreal) and in men in the 1945-1954 birth cohort independent of year of diagnosis. These data are consistent with an environmental cofactor for Kaposi's sarcoma which is likely to be a sexually transmitted agent.
authors.affiliation: Department of Health Care and Epidemiology, Faculty of Medicine, University of British Columbia, Vancouver, Canada.
authors.forename: M T
authors.initials: MT
authors.lastname: Schechter
authors.forename: S A
authors.initials: SA
authors.lastname: Marion
authors.forename: K D
authors.initials: KD
authors.lastname: Elmslie
authors.forename: M N
authors.initials: MN
authors.lastname: Ricketts
authors.forename: P
authors.initials: P
authors.lastname: Nault
authors.forename: C P
authors.initials: CP
authors.lastname: Archibald
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000453:epidemiology; D002170:Canada / Q000453:epidemiology; D015331:Cohort Studies; D005843:Geography; D006716:Homosexuality; D006801:Humans; D008297:Male; D011159:Population Surveillance; D012044:Regression Analysis; D012307:Risk Factors; D012514:Sarcoma, Kaposi / Q000453:epidemiology / Q000209:etiology*; D012749:Sexually Transmitted Diseases / Q000453:epidemiology / Q000209:etiology