Penetration of stimuli of fish skin for Acanthostomum brauni cercariae.
The cercaria of Acanthostomum brauni penetrates the skin of its fish host in response to a combination of two chemical signals from the fish skin surface: free fatty acids and a macro-molecular mucus component. The latter seems to be a protein, as the penetration-stimulating activity of fish skin surface mucus is eliminated by digestion with proteinase, but not by digestion with glycosidases, nor by a removal of glycosaminoglycans. These penetration-stimulating host signals differ from the glycoproteins that stimulate the attachment of A. brauni cercariae to the host and also from the macromolecular fish host signals which have been found to stimulate the attachment and penetration by Opisthorchis viverrini cercariae.
Ostrowski de Nuñez
M
M
Institut für Zoologie I, Universität Erlangen-Nürnberg, Federal Republic of Germany.
Haas
W
W
D000818:Animals; D002347:Carps / Q000469:parasitology*; D002809:Chondroitin Sulfates / Q000494:pharmacology; D010450:Endopeptidases / Q000378:metabolism; D005227:Fatty Acids / Q000502:physiology; D006026:Glycoside Hydrolases / Q000378:metabolism; D006790:Host-Parasite Interactions; D006820:Hyaluronic Acid / Q000494:pharmacology; D009077:Mucins / Q000494:pharmacology; D009093:Mucus / Q000502:physiology; D011506:Proteins / Q000502:physiology; D012867:Skin / Q000737:chemistry / Q000378:metabolism / Q000469:parasitology*; D014200:Trematoda / Q000502:physiology*
D005227:Fatty Acids; D009077:Mucins; D011506:Proteins; D006820:Hyaluronic Acid; D002809:Chondroitin Sulfates; D006026:Glycoside Hydrolases; D010450:Endopeptidases