Trial of flecainide acetate in the management of tinnitus.
A two-phase trial of flecainide acetate in the management of tinnitus has been carried out in 22 patients with severe long-term tinnitus resistant to other treatments. Although 5 (23%) patients reported some limited benefit the results are not conclusive but suggest that, for such patients, flecainide deserves a place as a drug worth considering as a last resort, with the prospect of it occasionally giving a worthwhile degree of relief.
Fortnum
H M
HM
MRC Institute of Hearing Research, Nottingham University, UK.
Coles
R R
RR
D000368:Aged; D004311:Double-Blind Method; D005260:Female; D005424:Flecainide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014012:Tinnitus / Q000188:drug therapy*
D005424:Flecainide