title: [Two cases of Ewing's sarcoma originating from the adult rib].
abstract: Two cases of Ewing's sarcoma originating from the adult rib were reported. Case 1: A 23-year-old male was admitted for further examination of a right anterior chest wall tumor. The tumor was resected and the pathological examination revealed Ewing's sarcoma. Adriamycin, vincristine, cyclophosphamide and actinomycin-D were administered. After 1 year the patient died due to local relapse. Case 2: A 28-year-old male was found to have a left extrapleural tumor on chest roentgenogram. He responded to chemotherapy consisting of CDDP, etoposide, ifosfamide and radiotherapy at a dose of 38.4 Gy before surgery. On the surgical specimen no tumor cells were observed and his postoperative course has been good. According to our experience, exact preoperative diagnosis and adjuvant therapy are necessary to improve the prognosis of Ewing's sarcoma patient.
authors.affiliation: First Department of Internal Medicine, Asahikawa Medical College, National Douhoku Hospital.
authors.forename: S
authors.initials: S
authors.lastname: Ishida
authors.forename: Y
authors.initials: Y
authors.lastname: Akiba
authors.forename: Y
authors.initials: Y
authors.lastname: Ohosaki
authors.forename: S
authors.initials: S
authors.lastname: Onodera
authors.forename: Y
authors.initials: Y
authors.lastname: Fujita
authors.forename: S
authors.initials: S
authors.lastname: Tagaki
authors.forename: T
authors.initials: T
authors.lastname: Shimizu
authors.forename: E
authors.initials: E
authors.lastname: Sakai
authors.forename: Y
authors.initials: Y
authors.lastname: Ikushima
authors.forename: K
authors.initials: K
authors.lastname: Saotome
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D005047:Etoposide / Q000008:administration & dosage; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D008297:Male; D009364:Neoplasm Recurrence, Local; D012272:Ribs; D012512:Sarcoma, Ewing / Q000188:drug therapy* / Q000473:pathology / Q000532:radiotherapy
chemical_list: D005047:Etoposide; D002945:Cisplatin; D007069:Ifosfamide