Cerebral oedema with coning in diabetic keto-acidosis. Report of 2 survivors.
Two children presented with a first episode of diabetic ketoacidosis. Initially both patients made a good clinical and biochemical recovery, but suddenly developed neurological signs consistent with a diagnosis of tentorial herniation. Cranial computed tomography showed signs of cerebral oedema in both cases with evidence of uncal and tentorial herniation in 1 patient, which resolved after the appropriate treatment. The excellent neurological outcome emphasises the need for early recognition and treatment of sudden onset brain oedema in diabetic keto-acidosis.
Kalis
N N
NN
Department of Paediatrics, University of Stellenbosch.
van der Merwe
P L
PL
Schoeman
J F
JF
Smith
R M
RM
D001921:Brain / Q000000981:diagnostic imaging; D001929:Brain Edema / Q000000981:diagnostic imaging / Q000209:etiology*; D002648:Child; D016883:Diabetic Ketoacidosis / Q000150:complications*; D005260:Female; D006801:Humans; D014057:Tomography, X-Ray Computed