title: Presynaptic localization of omega-conotoxin-sensitive calcium channels at the frog neuromuscular junction.
abstract: By the use of anti-omega-CTx antibodies in indirect immunofluorescence we demonstrated the presence of omega-CTx binding sites in the presynaptic compartment of frog nerve-muscle preparations. The images we obtained indicate that omega-CTx-sensitive channels are clustered at discrete sites corresponding in distribution to active zones.
authors.affiliation: Department of Medical Pharmacology, Bruno Ceccarelli Center for the Study of Peripheral Neuropathies and Neuromuscular Diseases, Milan, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Torri Tarelli
authors.forename: M
authors.initials: M
authors.lastname: Passafaro
authors.forename: F
authors.initials: F
authors.lastname: Clementi
authors.forename: E
authors.initials: E
authors.lastname: Sher
mesh_terms: D000818:Animals; D001001:Anura; D002121:Calcium Channel Blockers / Q000494:pharmacology*; D005455:Fluorescent Antibody Technique; D066298:In Vitro Techniques; D009469:Neuromuscular Junction / Q000737:chemistry / Q000187:drug effects*; D010456:Peptides, Cyclic / Q000494:pharmacology*; D020960:omega-Conotoxins
chemical_list: D002121:Calcium Channel Blockers; D010456:Peptides, Cyclic; D020960:omega-Conotoxins; C053423:Conus magus toxin