Fungal peritonitis in children treated with peritoneal dialysis and gastrostomy feeding.
Feeding gastrostomies were placed in three children treated with chronic peritoneal dialysis at our center because of persistent, severe malnutrition and inadequate growth. Two had frequent fungal infections of the gastrostomy site and all three developed Candida peritonitis which occurred at 1 month, 2 months and 2 years after insertion of gastrostomy. Complications included multiple intra-abdominal adhesions, abscess formation and loss of peritoneal function necessitating transfer to hemodialysis. The presence of a gastrostomy may predispose to the development of fungal peritonitis with its high morbidity and should be avoided in children on chronic peritoneal dialysis.
Murugasu
B
B
Department of Pediatrics, University of Texas Medical School, Houston 77030.
Conley
S B
SB
Lemire
J M
JM
Portman
R J
RJ
D000293:Adolescent; D000666:Amphotericin B / Q000627:therapeutic use; D002177:Candidiasis / Q000635:transmission*; D002648:Child; D002675:Child, Preschool; D000075202:Contraindications; D004750:Enteral Nutrition; D005260:Female; D005774:Gastrostomy; D006801:Humans; D008297:Male; D010530:Peritoneal Dialysis; D010538:Peritonitis / Q000382:microbiology* / Q000473:pathology
D000666:Amphotericin B