title: Comparison of patient-controlled and nurse-controlled antiemetic therapy in patients receiving chemotherapy.
abstract: The purpose of this quasi-experimental pilot study was to compare the effect of patient-controlled (PCAE) and nurse administered (NCAE) antiemetic therapy for controlling chemotherapy-induced nausea and vomiting in patients receiving moderate emetogenic chemotherapy. Twenty subjects were randomly assigned to either the PCAE group who received IV antiemetic medication via a patient-controlled pump or the NCAE group who received antiemetic medication via nurse administered minibags. Nausea, vomiting, sedation, and drug consumption were measured. There was no difference in nausea scores between the two groups. Subjects in the PCAE group consumed significantly less medication than subjects in the NCAE group.
authors.affiliation: Cancer Program, McLeod Regional Medical Center, Florence, SC.
authors.forename: J N
authors.initials: JN
authors.lastname: Edwards
authors.forename: J A
authors.initials: JA
authors.lastname: Herman
authors.forename: B K
authors.initials: BK
authors.lastname: Wallace
authors.forename: M D
authors.initials: MD
authors.lastname: Pavy
authors.forename: J
authors.initials: J
authors.lastname: Harrison-Pavy
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016058:Analgesia, Patient-Controlled / Q000295:instrumentation*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D004155:Diphenhydramine / Q000008:administration & dosage* / Q000627:therapeutic use; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008787:Metoclopramide / Q000008:administration & dosage* / Q000627:therapeutic use; D008875:Middle Aged; D009325:Nausea / Q000139:chemically induced / Q000188:drug therapy* / Q000451:nursing; D009732:Nursing Care / Q000592:standards*; D010865:Pilot Projects; D012648:Self Care / Q000592:standards*
chemical_list: D000970:Antineoplastic Agents; D004155:Diphenhydramine; D008787:Metoclopramide