Growth inhibition observed following administration of an LHRH agonist to a clonal variant of the MCF-7 breast cancer cell line is accompanied by an accumulation of cells in the G0/G1 phase of the cell cycle.
Mullen
P
P
I.C.R.F., Medical Oncology Unit, Western General Hospital, Edinburgh, UK.
Scott
W N
WN
Miller
W R
WR
D001943:Breast Neoplasms; D002064:Buserelin / Q000494:pharmacology*; D002453:Cell Cycle / Q000187:drug effects*; D002460:Cell Line; D002999:Clone Cells; D005260:Female; D016193:G1 Phase / Q000187:drug effects*; D007987:Gonadotropin-Releasing Hormone / Q000037:antagonists & inhibitors*; D006801:Humans; D007700:Kinetics; D016192:Resting Phase, Cell Cycle / Q000187:drug effects*
D007987:Gonadotropin-Releasing Hormone; D002064:Buserelin