title: [The 5-fluorouracil content of the pancreas and parapancreatic tissues when it is administered regionally into the tissue of the round ligament of the liver].
abstract: In the experiment on 31 dogs there was shown a significant increase of 5-fluorouracil concentrations in the pancreas and parapancreatic tissues with regional methods of its administration in the fat of the round ligament of the liver. A more prolonged preservation of the drug concentrations at the therapeutic level in the blood was observed. The most effective method of the cytostatic therapy is the regional lymphotropic method.
authors.forename: K Iu
authors.initials: KIu
authors.lastname: Danilov
authors.forename: N S
authors.initials: NS
authors.lastname: Brodinova
authors.forename: S V
authors.initials: SV
authors.lastname: Kharitonov
authors.forename: I V
authors.initials: IV
authors.lastname: Sorokin
authors.forename: E I
authors.initials: EI
authors.lastname: Zaranko
mesh_terms: D000818:Animals; D010478:Chemotherapy, Cancer, Regional Perfusion; D004285:Dogs; D005472:Fluorouracil / Q000008:administration & dosage / Q000032:analysis / Q000493:pharmacokinetics*; D006470:Hemorrhage / Q000378:metabolism; D007272:Injections, Intralymphatic; D007275:Injections, Intravenous; D008022:Ligaments; D008099:Liver; D009336:Necrosis; D010179:Pancreas / Q000737:chemistry / Q000378:metabolism* / Q000473:pathology; D010182:Pancreatic Diseases / Q000378:metabolism
chemical_list: D005472:Fluorouracil
vernacular_title: Soderzhanie 5-ftoruratsila v podzheludochnoĭ zheleze i parapankreaticheskikh tkaniakh pri regionarnykh sposobakh ego vvedeniia v kletchatku krugloĭ sviazki pecheni.