title: Dopa-responsive dystonia masquerading as idiopathic kyphoscoliosis.
abstract: A 19-year-old girl with a long-standing history of kyphoscoliosis misdiagnosed as idiopathic was offered corrective surgery on several occasions but fortunately refused, since neurological examination later found evidence of mild dystonic posturing in the neck and right leg. Symptoms worsened toward evening but improved with rest. Treatment with low doses of levodopa led to total remission within a month. Our case illustrates that dopa-responsive dystonia can manifest spinal curvature as the major symptom and warrants its inclusion in the differential diagnoses of idiopathic kyphoscoliosis.
authors.affiliation: Hospital de Clinicas José de San Martin, Neurology Department, University of Buenos Aires, Argentina.
authors.forename: F
authors.initials: F
authors.lastname: Micheli
authors.forename: M F
authors.initials: MF
authors.lastname: Pardal
authors.forename: E
authors.initials: E
authors.lastname: Gatto
authors.forename: G
authors.initials: G
authors.lastname: Paradiso
mesh_terms: D000328:Adult; D002940:Circadian Rhythm; D003937:Diagnosis, Differential; D004295:Dihydroxyphenylalanine / Q000627:therapeutic use*; D004421:Dystonia / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D006801:Humans; D007738:Kyphosis / Q000175:diagnosis*; D012600:Scoliosis / Q000175:diagnosis*
chemical_list: D004295:Dihydroxyphenylalanine