title: Cholesteatoma in an Asian population.
abstract: Two hundred Malaysian patients representing 227 ears with previously untreated cholesteatoma disease were analysed retrospectively in terms of i) type of disease, i.e. primary acquired attic defect or posterior superior retraction pocket and secondary acquired type cholesteatoma; ii) positive history of previous middle ear effusion, atelectasis or grommet insertion; and iii) likelihood of complications as initial presenting feature. The high 47.1% incidence of secondary acquired cholesteatoma disease in our patients contrasts with the predominance of primary acquired cholesteatoma in the Caucasian patient. Correlation of these two disease types with a positive history showed a significant positive association between the primary acquired group and a positive history; and conversely a significant negative association for the secondary acquired type. This supports a role for the retraction theory in primary acquired cholesteatoma but negates this theory in secondary acquired cholesteatoma. Secondary acquired cholesteatoma had a significantly higher (35.5%) complication rate against 15.8% in the primary acquired type (p = 0.001). This fact together with a 47.1% incidence of secondary acquired disease, low otolaryngologist population ratio and patient attitudes to disease account for the high total complication rate of 27.3%.
authors.affiliation: Department of Otorhinolaryngology, Faculty of Medicine, University of Malaya, Kuala Lumpur.
authors.forename: S T
authors.initials: ST
authors.lastname: Lee
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002781:Cholesteatoma / Q000150:complications / Q000453:epidemiology* / Q000209:etiology; D004427:Ear Diseases / Q000150:complications / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D008296:Malaysia / Q000453:epidemiology; D010034:Otitis Media with Effusion / Q000150:complications; D011379:Prognosis; D001261:Pulmonary Atelectasis / Q000150:complications; D012189:Retrospective Studies