Suppression of penicillin-induced lysis of Staphylococcus aureus by cibacron blue 3G-A.
The effect of cibacron blue 3G-A (CB) on bacteriolysis induced by penicillin G was investigated using Staphylococcus aureus FDA 209P. Penicillin-induced lysis was completely inhibited by 30 microM CB. However, the bactericidal effect of penicillin G was not influenced by CB. These results indicate that a bacteriolytic process is not essential for penicillin to kill S. aureus.
Sugai
M
M
Department of Microbiology, Hiroshima University School of Dentistry, Japan.
Ooku
K
K
Akiyama
T
T
Inoue
S
S
Iseda
S
S
Miyake
Y
Y
Suginaka
H
H
D001433:Bacteriolysis / Q000187:drug effects*; D004396:Coloring Agents / Q000494:pharmacology*; D010400:Penicillin G / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects*; D014227:Triazines / Q000494:pharmacology*
D004396:Coloring Agents; D014227:Triazines; C012842:Cibacron Blue F 3GA; D010400:Penicillin G