title: [Agent-conditioned influence on carbohydrate metabolism and energy state in liver and lung of rats in endotoxic shock].
abstract: The pretreatment of rats with the substance LPH and LXU caused decrease of lethality in endotoxin shock and suppression of the following changes 6 hours post endotoxin: Increase of plasma ICDH activity, decrease in platelet count, decrease of the hepatic energy state and increase of the ATP content in the lung. The catabolic glucose metabolism during endotoxin shock was not influenced by LPH and LXU administration.
authors.affiliation: Institut für Pathologische Biochemie, Medizinischen Akademie, Carl Gustav Carus Dresden.
authors.forename: S
authors.initials: S
authors.lastname: Kopprasch
authors.forename: K
authors.initials: K
authors.lastname: Kociok
authors.forename: M
authors.initials: M
authors.lastname: Kohl
authors.forename: D W
authors.initials: DW
authors.lastname: Scheuch
mesh_terms: D000227:Adenine Nucleotides / Q000378:metabolism; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D004731:Endotoxins / Q000494:pharmacology; D004734:Energy Metabolism / Q000187:drug effects*; D004926:Escherichia coli; D007521:Isocitrate Dehydrogenase / Q000378:metabolism*; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008168:Lung / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D010976:Platelet Count; D051381:Rats; D011919:Rats, Inbred Strains; D012772:Shock, Septic / Q000097:blood / Q000378:metabolism*
chemical_list: D000227:Adenine Nucleotides; D001786:Blood Glucose; D004731:Endotoxins; D007521:Isocitrate Dehydrogenase
vernacular_title: Wirkstoffbedingte Beeinflussung des Kohlenhydratstoff-wechsels und Energiestatus in Leber und Lunge der Ratte beim Endotoxinshock.