title: Chiasmatic optic glioma.
abstract: Optic nerve glioma is a rare tumor usually occurring in small children. How these tumors should be treated, is a matter of controversy. Recommended treatment ranges from a wait-and-see policy to radical excision with or without subsequent radio- or chemotherapy. Comparative data on these lesion are limited, as there are no randomized investigations and long-term studies reported in the literature. In 11 patients interstitial radiotherapy was carried out, by the implantation of J-125 seeds following confirmation of the histological diagnosis. The results are compared with those of 10 patients who underwent only biopsy for histological confirmation. CT-stereotactic biopsy to verify the diagnosis with subsequent interstitial irradiation is presented as an alternative therapy for optic gliomas.
authors.affiliation: Department of Neurosurgery, University of Freiburg, Federal Republic of Germany.
authors.forename: M
authors.initials: M
authors.lastname: Mohadjer
authors.forename: A
authors.initials: A
authors.lastname: Etou
authors.forename: E
authors.initials: E
authors.lastname: Milios
authors.forename: R
authors.initials: R
authors.lastname: Baden
authors.forename: F
authors.initials: F
authors.lastname: Mundinger
mesh_terms: D000293:Adolescent; D000328:Adult; D001254:Astrocytoma / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D001706:Biopsy; D001918:Brachytherapy / Q000379:methods; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003390:Cranial Nerve Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D009897:Optic Chiasm / Q000473:pathology / Q000528:radiation effects / Q000601:surgery*
chemical_list: D007457:Iodine Radioisotopes