title: A comparison of serum and saliva paracetamol concentrations.
abstract: The relationship between serum and saliva paracetamol concentrations was investigated in twenty healthy volunteers. The plasma and saliva drug concentrations showed a significant correlation (r = 0.67). However the agreement between the two methods of measurement was poor with limits of agreement of -15.3 mg l-1 to +15.9 mg l-1 with mean sample values of 19.2 and 19.5 mg l-1 for plasma and saliva, respectively.
authors.affiliation: Anaesthetic Unit, St Thomas' Hospital, London.
authors.forename: M
authors.initials: M
authors.lastname: Smith
authors.forename: E
authors.initials: E
authors.lastname: Whitehead
authors.forename: G
authors.initials: G
authors.lastname: O'Sullivan
authors.forename: F
authors.initials: F
authors.lastname: Reynolds
mesh_terms: D000082:Acetaminophen / Q000097:blood / Q000493:pharmacokinetics*; D000328:Adult; D003124:Colorimetry; D006801:Humans; D012463:Saliva / Q000737:chemistry*
chemical_list: D000082:Acetaminophen