title: Cytokines: is there biological meaning?
abstract: In the immune system, amidst the bewildering array of cytokine functions, it is sometimes difficult to discern the relative physiological importance of functions that have been determined in tissue culture. Cytokine functions are indeed complex, but the analysis of relatively simple regulatory networks suggests that activities determined in vitro are highly relevant to genuine physiological functions.
authors.affiliation: Department of Immunology, University of Alberta, Edmonton, Canada.
authors.forename: T R
authors.initials: TR
authors.lastname: Mosmann
mesh_terms: D000818:Animals; D016207:Cytokines / Q000276:immunology*; D004804:Eosinophils / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000096:biosynthesis; D007371:Interferon-gamma / Q000276:immunology; D015847:Interleukin-4 / Q000276:immunology; D007896:Leishmaniasis / Q000276:immunology
chemical_list: D016207:Cytokines; D015847:Interleukin-4; D007073:Immunoglobulin E; D007371:Interferon-gamma