title: Integrated displays of aligned amino acid sequences and protein structures.
abstract: Programs of the Sun-4 workstation permit the combined display of a table of aligned amino acid sequences of a family of proteins, and a corresponding three-dimensional fold. Interactive facilities include the ability, to scroll through the sequences, to rotate the structure and to connect the examination of the sequences and the structure by selecting a portion of the sequences and automatically highlighting the corresponding region in the structure and vice versa. These programs are well suited to support applications such as the investigation of the structural or functional significance of conserved patterns of amino acids in the sequences of a family of proteins.
authors.affiliation: European Molecular Biology Laboratory, Heidelberg, FRG.
authors.forename: R
authors.initials: R
authors.lastname: Schnobel
mesh_terms: D000465:Algorithms; D000595:Amino Acid Sequence; D003116:Color; D003626:Data Display; D008838:Microcomputers; D008969:Molecular Sequence Data; D012984:Software; D014584:User-Computer Interface