title: Detection of Helicobacter pylori carriers by discriminant analysis of urea and pH levels in gastric juices.
abstract: An alternative approach to the problems inherent in current methods for detecting Helicobacter pylori carriers--that of being generally time-consuming, expensive, and not sufficiently sensitive--was devised by using the urea concentration and pH levels of gastric juices. A linear discriminant analysis of these variables, measured in 54 patients submitted to digestive endoscopy for gastritis, provided a mathematical formula for assigning the subjects (previously classified by other standard methods) to groups of either positive or negative H pylori carriers. The results obtained showed a correct classification in 52 out of 54 cases with only one false negative and one false positive case.
authors.affiliation: Laboratory of Clinical Pathology, Regina Elena Institute for Cancer, Rome, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Ameglio
authors.forename: M R
authors.initials: MR
authors.lastname: Abbolito
authors.forename: D
authors.initials: D
authors.lastname: Giannarelli
authors.forename: F
authors.initials: F
authors.lastname: Citarda
authors.forename: A
authors.initials: A
authors.lastname: Grassi
authors.forename: G M
authors.initials: GM
authors.lastname: Gandolfo
authors.forename: V
authors.initials: V
authors.lastname: Casale
mesh_terms: D000328:Adult; D002353:Carrier State / Q000175:diagnosis* / Q000378:metabolism; D016002:Discriminant Analysis; D005260:Female; D005750:Gastric Juice / Q000737:chemistry*; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000378:metabolism; D016480:Helicobacter pylori; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D014508:Urea / Q000032:analysis*
chemical_list: D014508:Urea