title: Nonleast-squares jackknife regression in drug design.
abstract: Nonleast-squares jackknife regression was applied to model a quantitative structure-activity relationship (QSAR) analysis of butyrophenones. Dependent physicochemical and dependent psychopharmacological parameters were correlated, and the robustness of the model was confirmed by resampling.
authors.affiliation: Research Group for Pharmacochemistry, Faculty of Medicine, University Johannisallee 32, Leipzig, Germany.
authors.forename: P P
authors.initials: PP
authors.lastname: Mager
mesh_terms: D000465:Algorithms; D000818:Animals; D002090:Butyrophenones / Q000737:chemistry; D004285:Dogs; D004333:Drug Administration Routes; D015195:Drug Design; D051381:Rats; D012044:Regression Analysis; D013329:Structure-Activity Relationship
chemical_list: D002090:Butyrophenones