title: [Periodic disease and pregnancy].
abstract: The authors report a case of familial Mediterranean fever in a pregnant woman treated with Colchicine. She delivered normally at term. A review of the literature shows that colchicine does not have a teratogenic effect which it was long thought to have. All the same it is best to carry out fetal karyotype examination using early amniocentesis. Furthermore, colchicine improves fertility which is disturbed in these patients and pregnancy has a good effect on the disease.
authors.affiliation: Clinique Gynécologique et Obstétricale, Centre Hospitalier Universitaire (Hôtel-Dieu), Rennes.
authors.forename: C
authors.initials: C
authors.lastname: Cousin
authors.forename: J C
authors.initials: JC
authors.lastname: Palaric
authors.forename: F
authors.initials: F
authors.lastname: Jacquemard
authors.forename: J
authors.initials: J
authors.lastname: Lucas
authors.forename: J R
authors.initials: JR
authors.lastname: Giraud
mesh_terms: D000328:Adult; D002985:Clinical Protocols; D003078:Colchicine / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D010505:Familial Mediterranean Fever / Q000188:drug therapy* / Q000235:genetics / Q000503:physiopathology; D005260:Female; D006801:Humans; D008597:Menstrual Cycle; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D003078:Colchicine
vernacular_title: Maladie périodique et grossesse.