title: Effect of postural stress on left ventricular performance using the continuous-wave Doppler technique.
abstract: To evaluate the effect of postural shifts on continuous-wave Doppler indices of left ventricular performance in normal man, we recorded Doppler signals suprasternally in 69 healthy volunteers, ranging in age from 20 to 86 years, in the supine position and 2 min after assumption of sitting and standing postures. All indices decreased progressively with increasing orthostasis: peak acceleration (PKA): 15.6 +/- 4.5 m/s2 to 14.0 +/- 4.0 m/s2 to 13.6 +/- 4.6 m/s2; peak velocity (PKV): 0.64 +/- 0.18 m/s to 0.58 +/- 0.17 m/s to 0.56 +/- 0.17 m/s; stroke distance (SD): 11.4 +/- 3.7 cm to 9.8 +/- 3.4 cm to 8.0 +/- 2.8 cm; SD x heart rate (VIH): 717 +/- 272 cm to 655 +/- 268 cm to 572 +/- 217 cm, from supine to sitting to standing, respectively (p less than 0.001). In contrast heart rate increased modestly from 62.4 +/- 10.0 bpm supine, to 66.9 +/- 12.4 bpm sitting, to 71.3 +/- 9.9 bpm standing (p less than .001). Similar postural changes in Doppler variables were seen in all three age groups (20 to 44 years; 45 to 64 years; and 65 to 86 years). Thus, orthostasis in normal subjects is accompanied by a reduction in all continuous-wave Doppler indices of left ventricular performance, regardless of age.
authors.affiliation: Laboratory of Behavioral Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224.
authors.forename: R A
authors.initials: RA
authors.lastname: Brown
authors.forename: K A
authors.initials: KA
authors.lastname: McCormick
authors.forename: P V
authors.initials: PV
authors.lastname: Vaitkevicius
authors.forename: J L
authors.initials: JL
authors.lastname: Fleg
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology; D001011:Aorta / Q000502:physiology; D001783:Blood Flow Velocity; D015150:Echocardiography, Doppler; D006339:Heart Rate; D006801:Humans; D008875:Middle Aged; D011187:Posture / Q000502:physiology*; D016277:Ventricular Function, Left