Lymphokines and the immune response: the central role of interleukin-2.
A number of recent and past reports on the in vitro and in vivo roles of interleukin-2, interleukin-4, interferon-gamma and tumor necrosis factor-beta suggest that interleukin-2 plays a general role in the immune response. The other three lymphokines often play directive roles that determine the kind of response that occurs.
Swain
S L
SL
University of California, San Diego.
D000818:Animals; D000917:Antibody Formation; D006801:Humans; D007111:Immunity, Cellular; D007371:Interferon-gamma / Q000276:immunology; D007376:Interleukin-2 / Q000096:biosynthesis / Q000276:immunology*; D015847:Interleukin-4 / Q000276:immunology; D008222:Lymphokines / Q000096:biosynthesis / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology; D016212:Transforming Growth Factor beta / Q000276:immunology
D007376:Interleukin-2; D008222:Lymphokines; D016212:Transforming Growth Factor beta; D015847:Interleukin-4; D007371:Interferon-gamma