title: Nematocidal principles in "oakmoss absolute" and nematocidal activity of 2,4-dihydroxybenzoates.
abstract: Nematocidal principles obtained from oakmoss absolute were identified as methyl 2,4-dihydroxy-3,6-di-methylbenzoate (2), ethyl 3-formyl-2,4-dihydroxy-6-methylbenzoate (4), and ethyl 5-chloro-3-formyl-2,4-dihydroxy-6-methylbenzoate (7). In relation to their structures, the nematocidal activity of 2,4-dihydroxybenzoates of methyl to tetradecyl was tested and the strongest activity was found in the octyl ester (minimal lethal concentration = 13 microM).
authors.affiliation: Faculty of Pharmaceutical Sciences, Kanazawa University, Japan.
authors.forename: A M
authors.initials: AM
authors.lastname: Ahad
authors.forename: Y
authors.initials: Y
authors.lastname: Goto
authors.forename: F
authors.initials: F
authors.lastname: Kiuchi
authors.forename: Y
authors.initials: Y
authors.lastname: Tsuda
authors.forename: K
authors.initials: K
authors.lastname: Kondo
authors.forename: T
authors.initials: T
authors.lastname: Sato
mesh_terms: D000818:Animals; D000969:Antinematodal Agents / Q000302:isolation & purification* / Q000494:pharmacology; D062385:Hydroxybenzoates / Q000302:isolation & purification / Q000494:pharmacology; D008011:Lichens / Q000032:analysis*; D013329:Structure-Activity Relationship
chemical_list: D000969:Antinematodal Agents; D062385:Hydroxybenzoates