Gold-associated lymphadenopathy in a patient with rheumatoid arthritis. Histologic and scanning electron microscopic features.
The histologic features of adenopathy associated with intramuscular injections of gold sodium thiomalate in a woman with rheumatoid arthritis are presented. We believe that the light microscopic features of the above process are sufficiently distinctive that a diagnosis of gold-associated lymphadenopathy could be rendered. A review of the literature revealed no descriptions of the light microscopic appearance of gold in lymph nodes. In this case, the diagnosis of gold-associated lymphadenopathy was confirmed by scanning electron microscopic studies.
Rollins
S D
SD
Department of Pathology, St. Louis University School of Medicine, Mo.
Craig
J P
JP
D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D005260:Female; D006052:Gold Sodium Thiomalate / Q000009:adverse effects*; D006801:Humans; D006965:Hyperplasia; D008198:Lymph Nodes / Q000473:pathology* / Q000648:ultrastructure; D008206:Lymphatic Diseases / Q000139:chemically induced*; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged
D006052:Gold Sodium Thiomalate