Magnesium sulphate as a new desensitizing agent.
Various desensitizing agents have been used in clinics to solve the problem of dentinal hypersensitivity (DH), but none of them has been shown to be consistently effective. We here introduce a new type of desensitizing agent, i.e. 4% magnesium sulphate with iontophoresis at 2mA for 3 min. These optimal conditions were determined by animal experiments, while only a minor effect on dentinal issues was observed within 4 weeks after the treatment. When this desensitizing agent was used to treat DH, the cure rate of 62.4% remained steady within the 25-week observation period, while some effect was achieved in all the subjects who participated in the study.
Liu
G H
GH
Faculty of Stomatology, Guanxi Medical College, Nanning, People's Republic of China.
Morimoto
M
M
D000328:Adult; D000368:Aged; D000818:Animals; D003804:Dentin / Q000187:drug effects / Q000648:ultrastructure; D003807:Dentin Sensitivity / Q000188:drug therapy*; D004285:Dogs; D005260:Female; D006801:Humans; D007478:Iontophoresis; D008278:Magnesium Sulfate / Q000008:administration & dosage / Q000737:chemistry / Q000627:therapeutic use*; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D009566:Nitrates / Q000627:therapeutic use; D017680:Potassium Compounds
D009566:Nitrates; D017680:Potassium Compounds; D008278:Magnesium Sulfate; C023844:potassium nitrate