title: Vitrectomy for premacular fibroplasia. Prognostic factors, long-term follow-up, and time course of visual improvement.
abstract: Two hundred seventy eyes with premacular fibroplasia consecutively treated by pars plana vitrectomy and membrane peeling were reviewed. This study is among the largest series with long-term follow-up reported to date. Visual improvement of two or more lines was achieved in 43% of eyes at 6 to 12 months, in 54% at 1 to 2 years, in 60% at 2 to 3 years, and in 58% at 3 to 5 years. Overall, complications occurred in 34 eyes (13%). Cataract progression after vitrectomy was noted in 106 (57%) of phakic eyes at 3 to 5 years, and 43 of these eyes underwent subsequent cataract extraction. Mean time to best visual acuity after vitrectomy was slightly less than 1 year for all eyes unless they had cataract worsening with subsequent cataract extraction (1.9 years). Significant factors affecting visual outcome were: preoperative lens status, visual acuity before vitrectomy, duration of preoperative symptoms of distortion and/or blurred vision, and the occurrence of intraoperative complications.
authors.affiliation: Retina Consultants, Ltd, St. Louis, MO 63110.
authors.forename: S R
authors.initials: SR
authors.lastname: Pesin
authors.forename: R J
authors.initials: RJ
authors.lastname: Olk
authors.forename: M G
authors.initials: MG
authors.lastname: Grand
authors.forename: I
authors.initials: I
authors.lastname: Boniuk
authors.forename: N P
authors.initials: NP
authors.lastname: Arribas
authors.forename: M A
authors.initials: MA
authors.lastname: Thomas
authors.forename: D F
authors.initials: DF
authors.lastname: Williams
authors.forename: D
authors.initials: D
authors.lastname: Burgess
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction; D005260:Female; D005355:Fibrosis; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008266:Macula Lutea / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012164:Retinal Diseases / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D012189:Retrospective Studies; D014792:Visual Acuity; D014821:Vitrectomy