title: EEG changes and platelet aggregation in experimental cerebral focal ischemia in rabbits.
abstract: Nine white New Zealand rabbits were submitted to internal carotid embolization with microspheres which caused a histologically verified focal cerebral ischemia. Six animals were sham-operated. EEG, QEEG, ECG, blood pressure, rectal temperature and platelet aggregation were monitored in basal conditions and one hour after ischemia. Embolized animals showed an increase in power density spectrum (PDS) and delta activity (0.15-3.70 Hz) and the appearance of platelet aggregation. The QEEG changes were correlated to the degree of platelet aggregation after ischemia.
authors.affiliation: Istituto Neurologico C. Mondino, Universita di Pavia, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Bo
authors.forename: V
authors.initials: V
authors.lastname: Cosi
authors.forename: A
authors.initials: A
authors.lastname: Taccola
authors.forename: A
authors.initials: A
authors.lastname: Romani
authors.forename: F
authors.initials: F
authors.lastname: Savoldi
mesh_terms: D000818:Animals; D001794:Blood Pressure; D001831:Body Temperature; D002545:Brain Ischemia / Q000097:blood / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D004569:Electroencephalography; D002542:Intracranial Embolism and Thrombosis / Q000150:complications; D008863:Microspheres; D010974:Platelet Aggregation; D011817:Rabbits