title: Influence of adrenalectomy on the odor detection performance of rats.
abstract: The influence of adrenalectomy (ADX) on the odor detection performance of male Long-Evans rats was assessed using high-precision olfactometry and a go/no-go operant signal detection task. Nonparametric signal detection measures of sensitivity and responsivity, as well as measures of S+ response latency, the number of aborted trials, and session time, were obtained in daily 250-trial test sessions prior to and after adrenalectomy. Four ADX animals were tested using the odorant pyridine, three using the odorant eugenol, and two using the odorant ethyl acetate. Nine other rats served as sham-operated controls. Neither odor detection nor related nonsensory performance measures were influenced by adrenalectomy or sham-operation procedures. These results imply that adrenalectomy has little or no influence on the odor detection performance of the rat.
authors.affiliation: Smell and Taste Center, School of Medicine, University of Pennsylvania, Philadelphia 19104-4283.
authors.forename: R L
authors.initials: RL
authors.lastname: Doty
authors.forename: J M
authors.initials: JM
authors.lastname: Risser
authors.forename: G M
authors.initials: GM
authors.lastname: Brosvic
mesh_terms: D000302:Adrenal Cortex / Q000502:physiology*; D000315:Adrenalectomy; D000818:Animals; D003216:Conditioning, Operant / Q000502:physiology; D003345:Corticosterone / Q000502:physiology; D004193:Discrimination Learning / Q000502:physiology; D008297:Male; D009812:Odorants; D051381:Rats; D011930:Reaction Time / Q000502:physiology; D012684:Sensory Thresholds / Q000502:physiology; D012903:Smell / Q000502:physiology*
chemical_list: D003345:Corticosterone