title: Sodium and potassium in the lens after exposure to radiation in the 300 nm wavelength region.
abstract: The possible change in sodium and potassium concentration in the lens after an in vivo exposure to radiation in the 300 nm wavelength region was investigated. Both lenses from 12 reference rats and from 80 unilaterally exposed rats were examined. The exposed rats were sacrificed in four groups: 6, 24, 72 and 168 h after exposure. The lenticular cation contents were determined using atomic absorption spectrophotometry. In exposed lenses the concentration of sodium increases whereas that of potassium decreases as the time after exposure increases. The rates of concentration change decrease as the time after exposure increases. The increase in sodium precedes the decrease in potassium. Furthermore, a slight increase in the concentration of sodium is registered, as the time after exposure increases, in the non-exposed contralateral lenses. The registered changes are believed to reflect the water balance in the lenses.
authors.affiliation: Department of Ophthalmology, Karolinska Institute, Stockholm, Sweden.
authors.forename: P G
authors.initials: PG
authors.lastname: Söderberg
mesh_terms: D000818:Animals; D007908:Lens, Crystalline / Q000378:metabolism / Q000528:radiation effects*; D008297:Male; D011188:Potassium / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values; D012964:Sodium / Q000378:metabolism*; D013054:Spectrophotometry, Atomic; D014466:Ultraviolet Rays
chemical_list: D012964:Sodium; D011188:Potassium