title: [The protective activity of the attenuated strain 15 of the Venezuelan equine encephalomyelitis virus in rodent infection via the respiratory tract].
abstract: Administration to rodents (Syrian hamsters, mice, guinea pigs, rabbits) of minimal doses of attenuated strain 15 VEE (up to 20 ImD50) provided protection against respiratory challenge with a highly virulent strain of Venezuelan equine encephalomyelitis virus. The protection is observed in a wide range of doses (up to LD50 hundreds and even thousands).
authors.forename: A G
authors.initials: AG
authors.lastname: Filatenkov
authors.forename: G G
authors.initials: GG
authors.lastname: Khaltaeva
authors.forename: N N
authors.initials: NN
authors.lastname: Khlebnikova
authors.forename: S G
authors.initials: SG
authors.lastname: Gorban'
authors.forename: N N
authors.initials: NN
authors.lastname: Shkurnikova
authors.forename: M F
authors.initials: MF
authors.lastname: Khamitova
mesh_terms: D000818:Animals; D006224:Cricetinae; D004353:Drug Evaluation, Preclinical; D004666:Encephalitis Virus, Venezuelan Equine / Q000276:immunology* / Q000472:pathogenicity; D004685:Encephalomyelitis, Venezuelan Equine / Q000209:etiology / Q000517:prevention & control*; D006168:Guinea Pigs; D007114:Immunization; D008647:Mesocricetus; D051379:Mice; D011817:Rabbits; D012141:Respiratory Tract Infections / Q000209:etiology / Q000517:prevention & control*; D012376:Rodent Diseases / Q000209:etiology / Q000517:prevention & control*; D012692:Serial Passage; D014613:Vaccines, Attenuated / Q000008:administration & dosage / Q000276:immunology; D014765:Viral Vaccines / Q000008:administration & dosage / Q000276:immunology*; D014774:Virulence
chemical_list: D014613:Vaccines, Attenuated; D014765:Viral Vaccines
vernacular_title: Protektivnaia aktivnost' attenirovannogo shtamma 15 virusa venesuél'skogo éntsefalomielita loshadeĭ pri infitsirovanii gryzunov cherez dykhatel'nye puti.