title: Median lip fissure: etiology and suggested treatment.
abstract: In a prospective study of 20 patients with median lip fissure, pedigrees were obtained. A hereditary predisposition for weakness in the first branchial arch fusion seems to exist. In some persons, more often in males than in females, this weakness eventually leads to development of a median lip fissure. The fissure becomes symptomatic when it is infected. In 10 patients the fissure was excised; in the other 10 patients excision was done in combination with a Z-plasty of the center of the lesion. The prognosis with the latter operation was superior to that with the former.
authors.affiliation: Maxillofacial Unit, Malmö General Hospital, Sweden.
authors.forename: B
authors.initials: B
authors.lastname: Rosenquist
mesh_terms: D000328:Adult; D001284:Atrophy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006965:Hyperplasia; D008047:Lip Diseases / Q000209:etiology* / Q000235:genetics / Q000473:pathology / Q000601:surgery; D008297:Male; D008722:Methods; D008875:Middle Aged; D009504:Neutrophils / Q000473:pathology; D010375:Pedigree; D011379:Prognosis; D014945:Wound Healing