title: [The ultrastructural organization of Brucella L forms and revertant cultures].
abstract: The submicroscopic organization of Brucella cells in the process of L-transformation and reversion has been studied. As revealed in this study, at its initial stages L-transformation is accompanied by the loss of cell-wall peptidoglycan and by considerable polymorphism of Brucella cells. Further stages are characterized by the presence of a great number of closed annular membrane structures both in the cytoplasm and outside the cells. At late stages of L-transformation the destruction of the cytoplasm and the cells has been found to occur. In revertant cultures the restoration of the cell wall has been noted.
authors.forename: I A
authors.initials: IA
authors.lastname: Bazikov
authors.forename: A I
authors.initials: AI
authors.lastname: Bondarenko
mesh_terms: D000818:Animals; D002002:Brucella / Q000187:drug effects / Q000648:ultrastructure*; D002003:Brucella abortus / Q000187:drug effects / Q000648:ultrastructure; D002642:Chick Embryo; D003470:Culture Media; D004359:Drug Therapy, Combination / Q000494:pharmacology; D005998:Glycine / Q000494:pharmacology; D007740:L Forms / Q000187:drug effects / Q000648:ultrastructure*; D008854:Microscopy, Electron; D010400:Penicillin G / Q000494:pharmacology; D010401:Penicillin G Benzathine / Q000494:pharmacology; D010402:Penicillin G Procaine / Q000494:pharmacology; D012692:Serial Passage
chemical_list: D003470:Culture Media; C024657:benzathine benzylpenicillin, procaine benzylpenicillin, drug combination; D010402:Penicillin G Procaine; D010400:Penicillin G; D010401:Penicillin G Benzathine; D005998:Glycine
vernacular_title: Ul'trastrukturnaia organizatsiia L-form brutsell i kul'tur-revertantov.