Mammalian cartilage synthesizes both proteoglycan and non-proteoglycan forms of type IX collagen.
Bovine epiphysial cartilage synthesizes both proteoglycan (PG) and non-PG forms of type IX collagen in a ratio of approx. 2:1. The PG form with its attached glycosaminoglycan on the alpha 2(IX) chain is the major form in the medium, whereas both forms are found in the tissue. The results are discussed with regard to cartilage matrix organization.
Ayad
S
S
Department of Biochemistry and Molecular Biology, University of Manchester Medical School, U.K.
Marriott
A
A
Brierley
V H
VH
Grant
M E
ME
D000818:Animals; D002356:Cartilage / Q000378:metabolism*; D002417:Cattle; D003094:Collagen / Q000096:biosynthesis*; D004591:Electrophoresis, Polyacrylamide Gel; D005470:Fluorometry; D006132:Growth Plate / Q000378:metabolism; D011233:Precipitin Tests; D011509:Proteoglycans / Q000096:biosynthesis*
D011509:Proteoglycans; D003094:Collagen