title: Nonrandom t(1;22)(p12-p13;q13) in acute megakaryocytic malignant proliferation.
abstract: A case of acute megakaryocytic leukemia (M7) and one of acute myeloid hemopathy affecting megakaryocytic and erythrocytic cell lineages in infants are reported. Both patients had t(1;22)(p12-p13;q13). This translocation was previously observed in a congenital M7 leukemia. These studies suggest that t(1;22) translocation can be nonrandom in M7.
authors.affiliation: Service D'Hématologie Pédiatrique, Hôpital Saint-Louis, Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Baruchel
authors.forename: M T
authors.initials: MT
authors.lastname: Daniel
authors.forename: G
authors.initials: G
authors.lastname: Schaison
authors.forename: R
authors.initials: R
authors.lastname: Berger
mesh_terms: D002871:Chromosome Banding; D002878:Chromosomes, Human, Pair 1; D002892:Chromosomes, Human, Pair 22; D005260:Female; D006801:Humans; D007223:Infant; D007947:Leukemia, Megakaryoblastic, Acute / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic