title: Separation of human alloalbumin variants by isoelectric focusing.
abstract: A technique for the separation of human alloalbumin variants by means of isoelectric focusing in the presence of 8M urea and 60 mM L-serine is described. The potential usefulness of this technique in the detection and classification of genetic heterogeneity at the albumin locus is demonstrated by the differentiation of three human alloalbumin variants of European origin.
authors.affiliation: Instituto de Antropologia, Faculdade de Ciências, Universidade do Porto, Portugal.
authors.forename: J
authors.initials: J
authors.lastname: Rocha
authors.forename: J
authors.initials: J
authors.lastname: Kömpf
authors.forename: N
authors.initials: N
authors.lastname: Ferrand
authors.forename: A
authors.initials: A
authors.lastname: Amorim
authors.forename: H
authors.initials: H
authors.lastname: Ritter
mesh_terms: D005060:Europe; D014644:Genetic Variation; D006579:Heterozygote; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007525:Isoelectric Focusing / Q000379:methods*; D012694:Serine; D012709:Serum Albumin / Q000235:genetics / Q000302:isolation & purification*; D014508:Urea
chemical_list: D012709:Serum Albumin; D012694:Serine; D014508:Urea