Damage to the cytoplasmic membrane and cell death caused by dodine (dodecylguanidine monoacetate) in Pseudomonas syringae ATCC 12271.
Treatment of Pseudomonas syringae cells with low concentrations of the fungicide dodecylguanidine monoacetate (dodine) resulted in cell death and leakage of K+, UV-absorbing materials, and ribose-containing molecules. The results suggest that dodine causes gross and extensive damage to the cytoplasmic membrane, which is probably implicated in the death of cells.
Cabral
J P
JP
Instituto Nacional de Investigação Científica, Centro de Citologia Experimental da Universidade do Porto, Portugal.
D002470:Cell Survival / Q000187:drug effects*; D004396:Coloring Agents; D003593:Cytoplasm / Q000187:drug effects*; D005659:Fungicides, Industrial / Q000633:toxicity*; D006146:Guanidines / Q000633:toxicity*; D008566:Membranes / Q000187:drug effects / Q000378:metabolism; D011188:Potassium / Q000378:metabolism; D011549:Pseudomonas / Q000187:drug effects*; D012266:Ribose / Q000378:metabolism; D014466:Ultraviolet Rays
D004396:Coloring Agents; D005659:Fungicides, Industrial; D006146:Guanidines; C006921:dodine; D012266:Ribose; D011188:Potassium