[Diagnostic value of detection of blood levels of lactate, pyruvate and 2,3-diphosphoglycerate in children with diabetes mellitus].
Measurements were made of lactate, pyruvate and 2,3-diphosphoglycerate in 69 children admitted to the hospital in a state of diabetic ketoacidosis of different intensity. Depending on the intensity of metabolic abnormalities, the content of lactate and pyruvate was found to be increased, whereas that of 2,3-diphosphoglycerate to be lowered. Measurements of the content of lactate and the lactate/pyruvate ratio enables carrying out differential diagnosis between the ketoacidotic and lactacidotic varieties of diabetic coma.
Marchenko
L F
LF
Baturin
A A
AA
Terent'eva
E A
EA
D019794:2,3-Diphosphoglycerate; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000175:diagnosis*; D003926:Diabetic Coma / Q000097:blood / Q000175:diagnosis; D016883:Diabetic Ketoacidosis / Q000097:blood / Q000175:diagnosis; D003937:Diagnosis, Differential; D004163:Diphosphoglyceric Acids / Q000097:blood*; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D007773:Lactates / Q000097:blood*; D019344:Lactic Acid; D011773:Pyruvates / Q000097:blood*; D019289:Pyruvic Acid
D004163:Diphosphoglyceric Acids; D007773:Lactates; D011773:Pyruvates; D019794:2,3-Diphosphoglycerate; D019344:Lactic Acid; D019289:Pyruvic Acid
Diagnosticheskoe znachenie opredeleniia urovnia laktata, piruvata i 2,3-difosfoglitserata v krovi pri sakharnom diabete u deteĭ.