Non-Hodgkin's lymphoma accompanied by autoimmune hemolytic anemia with anti-e autoantibody.
A 43-year-old male with non-Hodgkin's lymphoma accompanied by autoimmune hemolytic anemia (AIHA). His blood group was group B, CcDEe. Alloantibody was absent in his serum, but autoantibody, a combination of IgG and C3d type which showed anti-e specificity, was present. Although transient improvement of AIHA was achieved by treatment with 60 mg/day of prednisolone, subsequent worsening of the anemia resulted in the patient's death. Identification of blood group-specific autoantibodies may be beneficial in such a case for blood transfusion.
Suzuki
K
K
First Department of Internal Medicine, Hirosaki University School of Medicine, Japan.
Murata
Y
Y
Shiotani
K
K
Kunikane
M
M
Fukuda
S
S
Yoshida
Y
Y
Kimura
A
A
Chiba
S
S
D000328:Adult; D001323:Autoantibodies / Q000032:analysis*; D005334:Fever / Q000209:etiology; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications / Q000276:immunology*; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000276:immunology*; D008297:Male; D012204:Rh-Hr Blood-Group System / Q000276:immunology*
D001323:Autoantibodies; D007074:Immunoglobulin G; D012204:Rh-Hr Blood-Group System