Thermogenic responses to noradrenaline are unaltered following energy supplementation in chronically energy-deficient human subjects.
A group of chronically undernourished labourers underwent a period of controlled supplementary feeding (3.35 MJ per day) over a period of 12 weeks. Thermogenic responses to Noradrenaline (NA) (0.15 microgram kg-1 fat-free mass per min) were assessed (1) before supplementation (2) during the 12th week of supplementation and (3) 12-16 weeks following the cessation of supplementation. There were significant changes in anthropometric indices and basal metabolic rates (BMR) during the three stages of the study; however, these were not accompanied by significant changes in the thermogenic responses to NA.
Vaz
M
M
Department of Physiology, St John's Medical College, Bangalore, India.
Kulkarni
R N
RN
Soares
M J
MJ
Kurpad
A V
AV
Shetty
P S
PS
D000328:Adult; D001481:Basal Metabolism / Q000187:drug effects / Q000502:physiology; D015992:Body Mass Index; D001833:Body Temperature Regulation / Q000187:drug effects* / Q000502:physiology; D002149:Energy Intake; D004734:Energy Metabolism / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008297:Male; D009638:Norepinephrine / Q000494:pharmacology* / Q000502:physiology; D009748:Nutrition Disorders / Q000178:diet therapy / Q000473:pathology / Q000503:physiopathology*; D010101:Oxygen Consumption / Q000187:drug effects / Q000502:physiology
D009638:Norepinephrine