Susceptibility of Mycoplasma pneumoniae to several new quinolones, tetracycline, and erythromycin.
Mycoplasma pneumoniae (39 strains) was most susceptible to two quinolones, WIN 57273 and sparfloxacin, with MICs for 90% of the strains (MIC90S) of 0.125 and 0.25 micrograms/ml, respectively. It was susceptible to ofloxacin and ciprofloxacin at 2 micrograms/ml and to lomefloxacin and fleroxacin at 4 micrograms/ml. The MIC90 of erythromycin was 0.062 microgram/ml, and that of tetracycline was 1 microgram/ml.
Kenny
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GE
Department of Pathobiology, University of Washington School of Public Health and Community Medicine, Seattle 98195.
Cartwright
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D000890:Anti-Infective Agents / Q000494:pharmacology*; D004917:Erythromycin / Q000494:pharmacology*; D024841:Fluoroquinolones; D008826:Microbial Sensitivity Tests; D009177:Mycoplasma pneumoniae / Q000187:drug effects*; D015242:Ofloxacin / Q000494:pharmacology*; D015363:Quinolones; D013752:Tetracycline / Q000494:pharmacology*
D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D015363:Quinolones; C062556:Win 57273; D004917:Erythromycin; D015242:Ofloxacin; D013752:Tetracycline; C053091:lomefloxacin; C061363:sparfloxacin