[Postoperative infections in otorhinolaryngologic surgery. Open study on efficacy and tolerability of antibiotic prophylactic treatment with sulbactam-ampicillin].
The paper reports the results of an open study on the efficacy and tolerability of the association of sulbactam-ampicillin in antibiotic prophylaxis in ENT surgery. The study include 55 cases and confirmed both the total absence of major side-effects and a notable therapeutic efficacy of the drug in question. It is interesting to note the results obtained in ENT cancer surgery: out of 12 cases of partial or total laryngectomies there were 2 cases of infection in extra-operative sites (polmoniti ab ingestis from Pseudomonas aeruginosa) and none within the site of operation. Data regarding the efficacy of the drug were in line or better than previously published results and its low toxicity indicates the elective use of sulbactam/ampicillin in ENT surgical prophylaxis.
Borloni
R
R
Istituto di Clinica Otorinolaringoiatrica II, Università degli Studi di Milano.
De Bellis
M
M
Felisati
G
G
D000293:Adolescent; D000328:Adult; D000368:Aged; D000667:Ampicillin / Q000008:administration & dosage*; D002648:Child; D004338:Drug Combinations; D004341:Drug Evaluation; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D017053:Infection Control; D008297:Male; D008875:Middle Aged; D010038:Otorhinolaryngologic Diseases / Q000601:surgery*; D011183:Postoperative Complications / Q000517:prevention & control; D011292:Premedication; D013407:Sulbactam / Q000008:administration & dosage*; D013530:Surgical Wound Infection / Q000517:prevention & control
D004338:Drug Combinations; D000667:Ampicillin; D013407:Sulbactam
Le infezioni postoperatorie in chirurgia otorinolaringoiatrica. Studio aperto su efficacia e tollerabilità del trattamento antibiotico-profilattico con sulbactam ampicillina.