Surgery following chemotherapy for metastatic testicular teratoma.
Twenty patients with metastatic testicular teratoma underwent surgery for residual disease after chemotherapy. Twelve patients in whom complete excision of all residual masses was possible are alive with no evidence of disease. Four patients have died of malignant teratoma, 2 have active malignant disease and 2 have inoperable residual cystic disease. Patients with malignant teratoma intermediate (MTI) primary testis tumours, and those with bulky abdominal disease at presentation, are more likely to have residual masses requiring excision. Completeness of excision appears to be the most important predictor of disease-free survival.
Whillis
D
D
Department of Clinical Oncology, Western General Hospital, Edinburgh.
Coleman
R E
RE
Lessells
A M
AM
Hargreave
T B
TB
Cornbleet
M A
MA
Howard
G C
GC
D000293:Adolescent; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D011379:Prognosis; D013724:Teratoma / Q000188:drug therapy* / Q000601:surgery*; D013736:Testicular Neoplasms / Q000188:drug therapy* / Q000601:surgery*