[The radioprotective effect of extracts of Archangelica officinalis Hoffm. and Ledum palustre L. on mice].
A single injection of Archangelica officinalis Hoffm. and Ledum palustre L. extracts to mice 5-15 min before irradiation with a median lethal dose increased their survival rate. The most favourable effect was produced by a combination of the two preparations: by day 30 100% of animals survived after a dose of 6 Gy (LD50/30); 70% survived after a dose of 7.5 Gy (LD90/30), and 25% after a dose of 8 Gy (LD100/12). DMF for the extract mixture was 1.48.
Narimanov
A A
AA
Miakisheva
S N
SN
Kuznetsova
S M
SM
D000818:Animals; D002588:Cesium Radioisotopes; D004338:Drug Combinations; D005720:Gamma Rays; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000008:administration & dosage / Q000627:therapeutic use*; D011833:Radiation Injuries, Experimental / Q000517:prevention & control*; D011837:Radiation-Protective Agents / Q000627:therapeutic use*
D002588:Cesium Radioisotopes; D004338:Drug Combinations; D010936:Plant Extracts; D011837:Radiation-Protective Agents
Radiozashchitnoe deĭstvie ékstraktov Archangelica officinalis Hoffm. i Ledum palustre L. na mysheĭ.