Prenatal paternity testing by DNA analysis.
Prenatal paternity testing was evaluated by DNA analysis in chorionic villus biopsies obtained during the 7th-22nd weeks of gestation. Using highly polymorphic variable number of tandem repeats (VNTR) probes, we analysed four cases consisting of mother/child/alleged father trios. In all cases, we were able to detect maternal and paternal alleles and could establish or exclude paternity. The application of DNA analysis represents a new important diagnostic aid for all cases that require a prenatal identification of paternity.
Lobbiani
A
A
Molecular Biology Laboratory, Clonit Sp A, Milan, Italy.
Nocco
A
A
Vedrietti
P
P
Brambati
B
B
Colucci
G
G
D015139:Blotting, Southern; D015193:Chorionic Villi Sampling; D004247:DNA / Q000032:analysis*; D005260:Female; D006801:Humans; D010334:Paternity; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second; D012091:Repetitive Sequences, Nucleic Acid
D004247:DNA