title: Regional variation in canine diaphragm thickness.
abstract: To quantify the relationship between both regional and overall diaphragm morphometry and body weight in the dog, diaphragm thickness was measured in five regions of the costal diaphragm and three regions of the crural diaphragm in 40 healthy dogs (8-40 kg). Surface area of the diaphragm, diaphragm weight, and body weight were also determined. Diaphragm surface area and weight varied linearly with body weight, but there was no significant correlation between overall diaphragm thickness and body weight. Diaphragm thickness varied significantly between regions, and three regions had systematic left-to-right differences as well. Because diaphragm geometry influences the diaphragm's function as a pressure generator, regional differences in thickness may alter the relationship between the force developed by the activation of a particular region of the diaphragm and its action on the respiratory system.
authors.affiliation: Division of Thoracic Diseases and Internal Medicine, Mayo Foundation, Rochester, Minnesota 55905.
authors.forename: S S
authors.initials: SS
authors.lastname: Margulies
mesh_terms: D000818:Animals; D001835:Body Weight; D003964:Diaphragm / Q000033:anatomy & histology* / Q000502:physiology; D004285:Dogs; D066298:In Vitro Techniques; D009929:Organ Size; D015656:Respiratory Mechanics / Q000502:physiology