Recognition of self within self: specific lymphocyte positioning and the extracellular matrix.
In this article, Maria de Sousa and colleagues address the importance of interactions between lymphocytes and extracellular matrix components to lymphocyte migration and positioning, emphasizing the role of the basement membrane and the complex stromal matrix of the lymphoid organs. They conclude that such interactions are of great importance, both in the physiological functioning of the immune system and in organ transplantation.
de Sousa
M
M
Institute for the Biomedical Sciences, Porto, Portugal.
Tilney
N L
NL
Kupiec-Weglinski
J W
JW
D000818:Animals; D002465:Cell Movement / Q000276:immunology; D005109:Extracellular Matrix / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology*; D051381:Rats; D014181:Transplantation Immunology