title: [Local administration of low-dose estriol and vital Lactobacillus acidophilus in postmenopause].
abstract: A randomized double-blind trial with 15 postmenopausal women led to a remarkable result. Local treatment with vaginal tablets just containing 0.03 mg estriol proved to be equivalent to the widely used dosage of 0.5 mg. The test drug Gynoflor E induced significant proliferation of the vaginal epithelium and thus offers the basis for a complete restoration of the vaginal environment. Simultaneously given Lactobacillus acidophilus can be implanted successfully and thus an acid vaginal milieu can be restored.
authors.forename: B
authors.initials: B
authors.lastname: Kanne
authors.forename: J
authors.initials: J
authors.lastname: Jenny
mesh_terms: D000282:Administration, Intravaginal; D000368:Aged; D002455:Cell Division / Q000187:drug effects; D002979:Climacteric / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004848:Epithelium / Q000187:drug effects; D004964:Estriol / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007779:Lactobacillus acidophilus; D008875:Middle Aged; D014621:Vagina / Q000187:drug effects*
chemical_list: D004964:Estriol
vernacular_title: Lokale Anwendung von schwachdosiertem Ostriol und lebensfähigen Döderlein-Keimen in der Postmenopause.