Structure of Lisch nodules in neurofibromatosis type 1.
Postmortem examination of the eyes of a patient with neurofibromatosis Type I was performed by light and electronmicroscopy. Lisch nodules were examined and found to consist of a condensation of spindle cells on the anterior iris surface. When nodules were pigmented an underlying stromal naevus was present. Lisch nodules are confirmed as being of melanocytic origin.
Williamson
T H
TH
Tennent Institute, Department of Ophthalmology, Western Infirmary, Glasgow, UK.
Garner
A
A
Moore
A T
AT
D006801:Humans; D007223:Infant; D007498:Iris / Q000648:ultrastructure*; D015811:Iris Neoplasms / Q000648:ultrastructure*; D008297:Male; D009456:Neurofibromatosis 1 / Q000473:pathology*; D009508:Nevus, Pigmented / Q000648:ultrastructure*