The production of antibacterial tubing, sutures, and bandages by in situ precipitation of metallic salts.
Two procedures were used to modify gauze bandages, polyester sutures, silicone tubing, and polyvinyl chloride tubing. In one procedure, the materials were first modified by in situ precipitation of metallic hydroxides and then used to adsorb silver ions. In the second procedure, the materials were soaked in sodium pyrophosphate or sodium chloride, dried, and then soaked in silver nitrate. These procedures produced materials with silver deposited on the surface of the tubing and sutures and both on the surface and within the gauze fibers. The modified materials inhibited the growth of Pseudomonas aeruginosa. Escherichia coli, and Staphylococcus aureus in vitro.
Farrah
S R
SR
Department of Microbiology and Cell Science, University of Florida, Gainesville 32611.
Erdos
G W
GW
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D001458:Bandages; D011232:Chemical Precipitation; D004926:Escherichia coli / Q000187:drug effects / Q000648:ultrastructure; D008670:Metals / Q000494:pharmacology*; D008855:Microscopy, Electron, Scanning; D011143:Polyvinyl Chloride; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000648:ultrastructure; D012828:Silicones; D012834:Silver / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development / Q000648:ultrastructure; D013537:Sutures
D000900:Anti-Bacterial Agents; D008670:Metals; D012828:Silicones; D012834:Silver; D011143:Polyvinyl Chloride