Clinical spectrum of myasthenia gravis and problems of management.
Seventeen cases of myasthenia gravis, aged 20-79 years, including one case of ocular myasthenia gravis, seen over a 3 year period, were analysed. Dysphagia was the presenting symptom in two cases. One patient had ectopic thymus gland in relation to the cardiac border, which posed difficulty in diagnosis. A majority of the patients were on medical treatment, including neostigmine, prednisolone and azathioprim. Plasmapheresis was done in 4 cases during crisis, with significant benefit. One patient was put on intermittent ventilatory support for 14-16 hours a day for over 2 years; she died during a power failure. Seven patients were subjected to thymectomy.
Dhamija
R M
RM
Anaesthetist, Neurocentre, Army Hospital, Delhi Cantt.
Venkataraman
S
S
Roy
A K
AK
Sanchetee
P C
PC
Bhargava
A K
AK
D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000175:diagnosis / Q000628:therapy*; D010276:Parasympatholytics / Q000008:administration & dosage; D010956:Plasmapheresis; D012121:Respiration, Artificial; D013256:Steroids / Q000008:administration & dosage; D013934:Thymectomy
D010276:Parasympatholytics; D013256:Steroids