title: Effect of ethyl apovincaminate on the utilization of 14C-glucoses by rat brain in vitro.
abstract: The effect of the presence of 500 micrograms ethyl epovincaminate (Cavinton) on the aerobic metabolism of 14C-labelled glucoses was studied in vitro. The drug tested increased the metabolism of [1-14C]-D-glucose first of all, which indicated a significant activation of pentose-phosphate shunt.
authors.affiliation: Biological Isotope Laboratory, Atilla József University, Szeged, Hungary.
authors.forename: B
authors.initials: B
authors.lastname: Matkovics
authors.forename: L
authors.initials: L
authors.lastname: Szabó
authors.forename: B
authors.initials: B
authors.lastname: Kiss
authors.forename: L
authors.initials: L
authors.lastname: Szpornyi
mesh_terms: D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects*; D002245:Carbon Dioxide / Q000378:metabolism; D005947:Glucose / Q000378:metabolism*; D066298:In Vitro Techniques; D010726:Phosphodiesterase Inhibitors / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D014748:Vinca Alkaloids / Q000494:pharmacology*
chemical_list: D010726:Phosphodiesterase Inhibitors; D014748:Vinca Alkaloids; D002245:Carbon Dioxide; C013983:vinpocetine; D005947:Glucose