The use of aztreonam in pediatric patients: a review.
Aztreonam is the first monobactam available for use in this country. A parenteral antibiotic, its antibacterial spectrum is limited to gram-negative aerobic pathogens. The drug's pharmacologic, pharmacokinetic, and toxicologic properties are reviewed. Based on early experience in pediatric patients, certain recommendations can be made for the use of aztreonam.
Bosso
J A
JA
University of Houston College of Pharmacy, TX 77030.
Black
P G
PG
D000328:Adult; D001398:Aztreonam / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy*; D006088:Gram-Negative Aerobic Bacteria; D006801:Humans; D007231:Infant, Newborn; D008581:Meningitis / Q000188:drug therapy; D011550:Pseudomonas aeruginosa; D012141:Respiratory Tract Infections / Q000188:drug therapy; D014552:Urinary Tract Infections / Q000188:drug therapy
D001398:Aztreonam