title: Evaluation of congenital heart disease by three-dimensional magnetic resonance imaging.
abstract: This study was undertaken to compare electrocardiographically gated magnetic resonance imaging (MRI) to established imaging modalities in the detection of complex intra- and extracardiac morphologic defects. Twenty-three patients with congenital cardiac abnormalities were imaged by four methods: cardiac catheterization, echocardiography, two-dimensional (2D) transaxial MRI, and three-dimensional (3D) MRI surface reconstruction. Observers with experience in congenital cardiac disease diagnosis (two for echo, one for catheterization, two for 2D MR, and three for 3D MR) evaluated the images in a blinded fashion, and the results were analyzed with receiver operating characteristic (ROC) analysis. Overall, cardiac catheterization had the best diagnostic performance. The diagnostic value of routine 2D cardiac MR images and 3D MR reconstruction images were similar to that of echocardiography. All of the modalities performed poorly in the diagnosis of extracardiac defects and atrial septal defects.
authors.affiliation: Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110.
authors.forename: M W
authors.initials: MW
authors.lastname: Vannier
authors.forename: F R
authors.initials: FR
authors.lastname: Gutierrez
authors.forename: C E
authors.initials: CE
authors.lastname: Canter
authors.forename: C F
authors.initials: CF
authors.lastname: Hildebolt
authors.forename: T K
authors.initials: TK
authors.lastname: Pilgram
authors.forename: R C
authors.initials: RC
authors.lastname: McKnight
authors.forename: J C
authors.initials: JC
authors.lastname: Laschinger
authors.forename: J J
authors.initials: JJ
authors.lastname: Brown
authors.forename: S A
authors.initials: SA
authors.lastname: Mirowitz
authors.forename: B D
authors.initials: BD
authors.lastname: Raisher
mesh_terms: D006328:Cardiac Catheterization; D002648:Child; D002675:Child, Preschool; D002932:Cineangiography; D004452:Echocardiography; D005069:Evaluation Studies as Topic; D006330:Heart Defects, Congenital / Q000175:diagnosis*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D007223:Infant; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012372:ROC Curve