title: [Fine needle aspiration biopsy (FNAG) guided with tomodensitometry of pulmonary and mediastinal masses. Personal experience].
abstract: CT-guided fine-needle aspiration biopsy (FNAB) was performed on the patients with pulmonary or mediastinal masses to obtain material for cytologic/histologic diagnosis. Diagnostic accuracy and safety of the technique were evaluated in 75 patients affected with thoracic lesions still undiagnosed after thorough radiological and endoscopic investigations. The cytologic and/or microhistologic samples allowed a correct diagnosis to be made in 61 cases (81%), with no false positives and 7 false negatives (9%). The samples were inadequate for diagnostic purposes in 7 cases (9%). Specificity, sensitivity, and diagnostic accuracy were 68%, 76%, and 81%, respectively. No major complication was recorded and a case of asymptomatic pneumothorax resolved spontaneously within 48 hours. CT-guided FNAB of space-occupying lesions in the lung and mediastinum is therefore a rapid and valuable diagnostic tool and is quite safe when performed by skilled operators.
authors.affiliation: Servizio di Radiologia, Ospedale Regina Apostolorum, Albano Laziale (RM).
authors.forename: C M
authors.initials: CM
authors.lastname: Pacella
authors.forename: E
authors.initials: E
authors.lastname: Papini
authors.forename: D
authors.initials: D
authors.lastname: Valle
authors.forename: E
authors.initials: E
authors.lastname: Buffa
authors.forename: G
authors.initials: G
authors.lastname: Bizzarri
authors.forename: Z
authors.initials: Z
authors.lastname: Rossi
authors.forename: F
authors.initials: F
authors.lastname: Nardi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000009:adverse effects / Q000379:methods; D002648:Child; D002675:Child, Preschool; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed
vernacular_title: La biopsia per aspirazione con ago sottile (FNAB) sotto guida tomodensitometrica (TC) delle masse polmonari e mediastiniche. Esperienza personale.