[Hemodynamic changes in patients with myocardial infarct complicated by acute left ventricular failure during combined nitroglycerin and dobutamine therapy].
A total of 18 patients with acute myocardial infarction complicated by acute left ventricular failure were examined for their central hemodynamics. Intravenous nitroglycerin was shown to cause positive changes in central hemodynamic parameters, but it failed to normalize the hemodynamics in patients with baseline low blood pressure, as nitroglycerin induced a further reduction in blood pressure. A combined administration of nitroglycerin and dobutamine solutions contributes to hemodynamic normalization and is indicated for patients with acute myocardial infarction complicated by acute left ventricular failure at a baseline low blood pressure.
Ol'binskaia
L I
LI
Poptsov
V N
VN
Gofman
A M
AM
D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D004280:Dobutamine / Q000008:administration & dosage / Q000494:pharmacology*; D004359:Drug Therapy, Combination; D005260:Female; D006333:Heart Failure / Q000150:complications / Q000503:physiopathology*; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D005996:Nitroglycerin / Q000008:administration & dosage / Q000494:pharmacology*
D004280:Dobutamine; D005996:Nitroglycerin
Izmeneniia gemodinamiki u bol'nykh infarktom miokarda, oslozhnennym ostroĭ levozheludochkovoĭ nedostatochnost'iu, pri kombinirovannoĭ terapii nitroglitserinom i dobutaminom.