T-cell-mediated activation of macrophages.
Functionally diverse subpopulations of macrophages and lymphocytes, a wide array of stimulatory signals, and an enormous effector repertoire of activated macrophages keeps this field dynamically active. We review new advances in the identification of cytokines that interact to activate macrophages, and in the discovery of effector molecules used by activated macrophages to destroy their targets.
Nacy
C A
CA
Cellular Immunology Branch, Walter Reed Army Institute of Research, Rockville, Maryland 20850.
Meltzer
M S
MS
D000818:Animals; D016207:Cytokines / Q000276:immunology; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000276:immunology; D006801:Humans; D007376:Interleukin-2 / Q000276:immunology; D015847:Interleukin-4 / Q000276:immunology; D008262:Macrophage Activation / Q000276:immunology*; D009569:Nitric Oxide / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*
D016207:Cytokines; D007376:Interleukin-2; D015847:Interleukin-4; D009569:Nitric Oxide; D016178:Granulocyte-Macrophage Colony-Stimulating Factor