title: [Diagnostic value of detection of blood levels of lactate, pyruvate and 2,3-diphosphoglycerate in children with diabetes mellitus].
abstract: Measurements were made of lactate, pyruvate and 2,3-diphosphoglycerate in 69 children admitted to the hospital in a state of diabetic ketoacidosis of different intensity. Depending on the intensity of metabolic abnormalities, the content of lactate and pyruvate was found to be increased, whereas that of 2,3-diphosphoglycerate to be lowered. Measurements of the content of lactate and the lactate/pyruvate ratio enables carrying out differential diagnosis between the ketoacidotic and lactacidotic varieties of diabetic coma.
authors.forename: L F
authors.initials: LF
authors.lastname: Marchenko
authors.forename: A A
authors.initials: AA
authors.lastname: Baturin
authors.forename: E A
authors.initials: EA
authors.lastname: Terent'eva
mesh_terms: D019794:2,3-Diphosphoglycerate; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000175:diagnosis*; D003926:Diabetic Coma / Q000097:blood / Q000175:diagnosis; D016883:Diabetic Ketoacidosis / Q000097:blood / Q000175:diagnosis; D003937:Diagnosis, Differential; D004163:Diphosphoglyceric Acids / Q000097:blood*; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D007773:Lactates / Q000097:blood*; D019344:Lactic Acid; D011773:Pyruvates / Q000097:blood*; D019289:Pyruvic Acid
chemical_list: D004163:Diphosphoglyceric Acids; D007773:Lactates; D011773:Pyruvates; D019794:2,3-Diphosphoglycerate; D019344:Lactic Acid; D019289:Pyruvic Acid
vernacular_title: Diagnosticheskoe znachenie opredeleniia urovnia laktata, piruvata i 2,3-difosfoglitserata v krovi pri sakharnom diabete u deteĭ.