Melanoma and the sun: the effect of swimsuits and a "healthy" tan on the risk of nonfamilial malignant melanoma in women.
The authors examined the relation between sun exposure and melanoma risk and tested the previously published site-specific association of bikini use and melanoma of the trunk in a study of 130 cases incident between 1976 and 1984 and 300 controls nested within the Nurses' Health Study. A summary variable derived from four measures of sun sensitivity was more closely associated with melanoma than any component measure. There was no association of bikini use at ages 15-20 years with trunk melanoma risk (relative risk (RR) = 0.8, p = 0.7), and the 95% confidence interval (CI) (0.3-2.6) excludes the previously published estimate. High frequency of swimsuit use outdoors at ages 15-20 years was associated with increased melanoma risk among sun-sensitive women (RR = 6.4, 95% CI 1.7-23.8, p = 0.006), but appeared to be protective among sun-resistant women (RR = 0.3, 95% CI 0.1-1.0, p = 0.06). These findings suggest that the risk of trunk melanoma associated with bikini use is at most modest and that sun-sensitive women may increase their risk of melanoma with frequent sun exposures, but that sun-resistant women do not, presumably because they develop a photoprotective tan.
Weinstock
M A
MA
Department of Medicine, Veterans Affairs Medical Center, Providence, RI 02908.
Colditz
G A
GA
Willett
W C
WC
Stampfer
M J
MJ
Bronstein
B R
BR
Mihm
M C
MC
Speizer
F E
FE
D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D003020:Clothing; D015331:Cohort Studies; D016001:Confidence Intervals; D005260:Female; D006801:Humans; D016015:Logistic Models; D008545:Melanoma / Q000209:etiology*; D010787:Photosensitivity Disorders / Q000150:complications; D012306:Risk; D012307:Risk Factors; D012878:Skin Neoplasms / Q000209:etiology*; D012880:Skin Pigmentation; D013471:Sunburn; D013472:Sunlight / Q000009:adverse effects*