title: [Optimization of the functional activity of the adrenal cortex in patients with sepsis].
abstract: The effect of hemosorption on adrenal steroidogenic reactions has been studied in 75 patients with sepsis. Different variants of steroidogenesis optimization have been used. Hemosorption led to an increase in the level of steroid hormones, with this background retained throughout the whole treatment period. The most effective of all the variants of stress adrenal steroidogenic reactions optimization was the application of B, B1, B6, B12 vitamin complex and taktivin. The least effective was the application of B vitamin complex, taktivin and ultraviolet blood irradiation. The technique elaborated makes it possible to avoid an increase in steroid blood level during treatment, which must have a favorable effect on the recovery of immune homeostasis in the patients.
authors.forename: V V
authors.initials: VV
authors.lastname: Spas
authors.forename: V V
authors.initials: VV
authors.lastname: Vinogradov
authors.forename: N I
authors.initials: NI
authors.lastname: Taranda
authors.forename: A N
authors.initials: AN
authors.lastname: Parfenov
mesh_terms: D000305:Adrenal Cortex Hormones / Q000097:blood*; D000328:Adult; D006464:Hemoperfusion; D006801:Humans; D007239:Infections / Q000628:therapy*; D008875:Middle Aged; D010455:Peptides / Q000627:therapeutic use*; D013268:Stimulation, Chemical; D013949:Thymus Extracts / Q000627:therapeutic use*; D014803:Vitamin B Complex / Q000627:therapeutic use*
chemical_list: D000305:Adrenal Cortex Hormones; D010455:Peptides; D013949:Thymus Extracts; D014803:Vitamin B Complex; C036191:T-activin
vernacular_title: Optimizatsiia funktsional'noĭ aktivnosti kory nadpochechnikov u bol'nykh sepsisom.