[Elimination of PCDF and PCB congeners in the blood of patients with PCB poisoning in Taiwan].
The blood of 3 Yu-cheng patients sampled from 1980 to 1989 were analyzed for congeners of polychlorinated dibenzofurans (PCDF) and polychlorinated biphenyls (PCB) by high resolution gas chromatography-mass spectrometry and gas chromatography-electron capture detection. The high concentrations of 2,3,4,7,8-penta-, 1,2,3,4,7,8-hexa- and 1,2,3,4,6,7,8-hepta-CDFs (15.4, 37.7 and 4.8 ppb in lipid basis, respectively) were eliminated from the blood at half-lives of 2.14, 2.56 and 2.32 years, respectively. The high concentrations of 8 PCB congeners in the blood were also decreased with time at half-lives of 1.16-4.56 years. The half-lives of retainable PCB congeners were about 2 times longer than those of the PCDF congeners.
Daiichi College of Pharmaceutical Sciences, Fukuoka, Japan.
Y
Y
Masuda
H
H
Kuroki
K
K
Haraguchi
J J
JJ
Ryan
S T
ST
Shu
D000328:Adult; D001572:Benzofurans / Q000097:blood*; D000072338:Dibenzofurans, Polychlorinated; D005260:Female; D006801:Humans; D008297:Male; D011041:Poisoning / Q000453:epidemiology; D011078:Polychlorinated Biphenyls / Q000097:blood / Q000506:poisoning*; D012189:Retrospective Studies; D013624:Taiwan / Q000453:epidemiology
D001572:Benzofurans; D000072338:Dibenzofurans, Polychlorinated; D011078:Polychlorinated Biphenyls