On the interaction of Trypanosoma cruzi neuraminidase and human lipoproteins.
Binding and penetration of Trypanosoma cruzi to host cells is a process that preludes infection and is mediated by specific recognition molecules. Neuraminidase is one of the parasite molecules involved in infection and, in this review, we describe some of its biochemical characteristics, its interaction with human lipoproteins and its effect on infection of mammalian cells.
Prioli
R P
RP
New England Medical Centre Hospitals, Department of Geographic Medicine and Infectious Diseases, Boston, MA 02111.
Mejia
J S
JS
Pereira
M E
ME
D000818:Animals; D014355:Chagas Disease / Q000201:enzymology / Q000469:parasitology; D006790:Host-Parasite Interactions / Q000502:physiology; D006801:Humans; D008075:Lipoproteins, HDL / Q000502:physiology*; D009439:Neuraminidase / Q000378:metabolism / Q000502:physiology*; D014349:Trypanosoma cruzi / Q000201:enzymology*
D008075:Lipoproteins, HDL; D009439:Neuraminidase