Simultaneous determination of carbamazepine and its major metabolites in human plasma and urine by HPLC.
A method is described for the analysis of carbamazepine and its major metabolites in biological fluids. The method uses a HPLC system based on a C18 Partisil column. The metabolites were extracted from chloroform in the presence of an internal standard. The method was specific, precise and reproducible.
Tsaprounis
C K
CK
Chelsea Department of Pharmacy, King's College London, U.K.
Kajbaf
M
M
Gorrod
J W
JW
D002220:Carbamazepine / Q000032:analysis* / Q000097:blood / Q000652:urine; D002851:Chromatography, High Pressure Liquid; D006801:Humans
D002220:Carbamazepine