[The effect of a high-saccharose diet on the enzymatic activity of the oral mucosa in rats].
Cathepsin D, acid phosphatase, beta-galactosidase, N-acetyl hexosaminidase, leucine aminopeptidase (LAP), lactate dehydrogenase, glucose-6-phosphate dehydrogenase (g-6-PDH), and peroxidase activities were measured in the buccal mucosa of rats kept for 60 days on high-sucrose (68% of sucrose) caries-inducing diet. The findings evidence that this diet observed for 30 days results in a significant elevation of beta-galactosidase and LAP activities and in reduction of peroxidase level. After 60-day diet the examined parameters virtually did not differ from the reference characteristics (a control group kept on 68% starch diet), except elevated g-6-PDH and lowered peroxidase activities. Enzymic activity changes are adaptive and evidence changes in the metabolic processes in the buccal mucosa, that may eventuate in the development of periodontal diseases.
T P
TP
Vavilova
L T
LT
Malyshkina
G I
GI
Tkachenko
N I
NI
Trunilina
D000818:Animals; D004040:Dietary Carbohydrates / Q000008:administration & dosage*; D009061:Mouth Mucosa / Q000201:enzymology*; D051381:Rats; D013395:Sucrose / Q000008:administration & dosage*; D013997:Time Factors
D004040:Dietary Carbohydrates; D013395:Sucrose
Vliianie vysokosakharoznoĭ diety na aktivnost' fermentov slizistoĭ obolochki polosti rta krys.