Slow excretion of exogenous human chorionic gonadotropin simulating repeated pregnancies and pregnancy losses.
We report a patient undergoing hMG-induced superovulation who demonstrated delayed excretion of hCG, originally believed to be because of successive biochemical pregnancies. However, sequential hCG titers after administration of exogenous hCG demonstrated a longer than normal half-life for the excretion of hCG in this patient. To what extent delayed excretion of hCG contributes to the diagnosis of biochemical pregnancy in assisted reproductive technology programs has yet to be determined.
Maier
D B
DB
Department of Obstetrics and Gynecology, University of Connecticut Health Center, Farmington 06030.
Metzger
D A
DA
D000328:Adult; D006063:Chorionic Gonadotropin / Q000493:pharmacokinetics / Q000627:therapeutic use / Q000652:urine*; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000628:therapy; D007317:Insemination, Artificial, Homologous; D008297:Male; D008596:Menotropins / Q000627:therapeutic use; D010062:Ovulation Induction; D011247:Pregnancy
D006063:Chorionic Gonadotropin; D008596:Menotropins