Abnormal cervical cytologic, colposcopic and histologic findings in exposed DES young Israeli Jewish women.
A consistently higher rate of abnormal cervical cytology, colposcopic and histologic findings in 89 DES exposed Israeli Jewish women was found as compared to 318 women in a control group. This trend however reached statistical significance for abnormal colposcopic and histologic findings only in the 25-34 age group. The higher rate of abnormal findings can be attributed to DES exposure and not to an excess of other risk factors in the study group. Routine cytologic and colposcopic examination is recommended for DES exposed Israeli Jewish women who are otherwise at low risk for development of cervical neoplasia.
Department of Obstetrics and Gynecology and Clinical Epidemiology, Chaim Sheba Medical Center, Tel Hashomer and Sackler School of Medicine, Tel Aviv University, Israel.
G
G
Ben-Baruch
O
O
Rothenberg
M
M
Modan
J
J
Menczer
D000328:Adult; D002278:Carcinoma in Situ / Q000473:pathology*; D003127:Colposcopy; D004054:Diethylstilbestrol / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007557:Israel; D007585:Jews; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D002583:Uterine Cervical Neoplasms / Q000473:pathology*
D004054:Diethylstilbestrol