Insulin binding to skeletal muscle microsomes in lactating and dry sheep.
Microsomes were prepared from skeletal muscles taken from lactating and non lactating ewes. Insulin binding to these microsomes was not affected by reproductive status. There were significant differences in the ability of individual muscles to bind insulin. These differences correlated with the function of the muscle, as defined by the predominant muscle fibre type.
Department of Agricultural Biochemistry and Nutrition, University of Newcastle upon Tyne, United Kingdom.
J A
JA
Metcalf
R G
RG
Vernon
D J
DJ
Flint
T E
TE
Weekes
D015720:5'-Nucleotidase / Q000378:metabolism; D000818:Animals; D005260:Female; D007328:Insulin / Q000378:metabolism*; D007774:Lactation / Q000378:metabolism*; D008861:Microsomes / Q000201:enzymology / Q000378:metabolism* / Q000648:ultrastructure; D009132:Muscles / Q000201:enzymology / Q000378:metabolism* / Q000648:ultrastructure; D012756:Sheep / Q000378:metabolism*
D007328:Insulin; D015720:5'-Nucleotidase