Treatment of tularemia with imipenem/cilastatin sodium.
A seriously ill patient with circulatory collapse, fever, acute renal failure, and progressive respiratory failure had dramatic improvement after treatment with imipenem/cilastatin sodium. During the treatment period, a diagnosis of tularemia was established serologically. This case suggests the efficacy of imipenem/cilastatin in the treatment of tularemia.
Department of Medicine, Creighton University Medical Center, Omaha, Neb. 68131.
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Horowitz
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D058186:Acute Kidney Injury / Q000188:drug therapy / Q000209:etiology*; D015377:Cilastatin / Q000627:therapeutic use*; D000077728:Cilastatin, Imipenem Drug Combination; D004338:Drug Combinations; D006801:Humans; D015378:Imipenem / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D014406:Tularemia / Q000150:complications / Q000188:drug therapy*
D004338:Drug Combinations; D015377:Cilastatin; D015378:Imipenem; D000077728:Cilastatin, Imipenem Drug Combination