Comparison of Novak and Pipelle endometrial biopsy instruments.
A randomized study compared the Novak and Pipelle endometrial biopsy instruments with respect to quality of the biopsy obtained and pain related to the procedure. Fifty-five subjects were randomized to one of two groups. Twenty-six women had a biopsy using the Pipelle, followed immediately by one using the Novak instrument; 29 had the procedures performed in the reverse sequence. After the procedures, each woman completed a pain questionnaire. Individual histology slides were reviewed in a blinded fashion. The two biopsies from each subject were paired, and a reviewer indicated the preferred type of biopsy. The scores were analyzed by nonparametric tests. The instruments yielded biopsies of similar quality (z = -0.18, P = .856). Pain scores were lower for the Pipelle (z = -3.40, P = .001). The pathologist showed no preference when choosing Novak or Pipelle slides (chi 2 = 2.08, P = .149). In our patient population, the Pipelle instrument was comparable to the Novak instrument in obtaining adequate tissue and was significantly less painful.
Silver
M M
MM
Department of Obstetrics and Gynecology, William Beaumont Army Medical Center, El Paso, Texas.
Miles
P
P
Rosa
C
C
D000328:Adult; D000368:Aged; D001706:Biopsy / Q000009:adverse effects / Q000295:instrumentation*; D002404:Catheterization / Q000009:adverse effects / Q000295:instrumentation; D003475:Curettage / Q000009:adverse effects / Q000295:instrumentation; D004717:Endometrium / Q000473:pathology*; D004867:Equipment Design; D005260:Female; D006652:Histological Techniques; D006801:Humans; D008875:Middle Aged; D010146:Pain / Q000517:prevention & control; D017060:Patient Satisfaction; D011126:Polypropylenes; D011897:Random Allocation; D013232:Steel; D013396:Suction / Q000009:adverse effects / Q000295:instrumentation
D011126:Polypropylenes; D013232:Steel