Analysis of the influence of aeroions on ECG and correlation between this action and tissue redox-state potential.
It was observed in rats, that following negative aeroionization heart frequency and the altitude of P-waves increased. After positive ionization these interrelationships took place inversely. As between these effects and the tendency of tissue redox-state potential changes correlation was seen, the results were grouped also on redox basis, independently on whether the increase or decrease of redox-state potential was caused by negative or positive aeroions. The results of this grouping showed, that following an elevation of tissue redox-state potential (+delta E'0) heart frequency dropped, and the altitude of T-waves increased. After a decrease of tissue redox-state potential (-delta E'0) these interrelationships were realized inversely. After -delta E'0 the positive chronotropic influence of noradrenaline increased, but consequent to +delta E'0 the classical positive chronotropic effect of this catecholamine was reversed. These results corroborate our earlier notion, that aeroions exert their action on heart through changing tissue redox-state potential.
Central Laboratory of Animal Experiments, University Medical School, Pécs, Hungary.
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Puppi
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Dely
D000818:Animals; D000838:Anions / Q000494:pharmacology*; D002412:Cations / Q000494:pharmacology*; D004562:Electrocardiography / Q000187:drug effects*; D005260:Female; D006339:Heart Rate / Q000187:drug effects / Q000502:physiology; D008297:Male; D009132:Muscles / Q000187:drug effects / Q000378:metabolism*; D009638:Norepinephrine / Q000494:pharmacology; D010084:Oxidation-Reduction; D051381:Rats
D000838:Anions; D002412:Cations; D009638:Norepinephrine