Modeling the kinetics of topically applied ophthalmic agents.
The equations for the ocular pharmacokinetics of topically applied agents are developed in a matrix form which is well suited to numerical solution on small computers. Some sample computations are presented. The technique is relatively simple to extend to additional compartments.
Wyatt
H J
HJ
State College of Optometry, State University of New York, New York.
D000287:Administration, Topical; D005123:Eye / Q000378:metabolism*; D006801:Humans; D008954:Models, Biological; D009883:Ophthalmic Solutions / Q000493:pharmacokinetics*
D009883:Ophthalmic Solutions