Persistent virus infections in studies of the immune response.
Some recent studies on immune phenomena in persistent virus infections, employing non-cytolytic viruses, are reviewed. This includes the refutation of a possible inheritance of tolerance and some aspects of drug-induced tolerance to persistent viruses, with its consequences for possible treatment of virus-induced immunopathological diseases. The biological peculiarities of viruses involved in persistent or chronic infections are discussed with respect to the balance between the immune system and the infectious agent.
Stitz
L
L
Institut für Virologie, Justus-Liebig-Universität Giessen, Germany.
D000818:Animals; D002908:Chronic Disease; D006801:Humans; D008216:Lymphocytic Choriomeningitis / Q000276:immunology; D008217:Lymphocytic choriomeningitis virus / Q000472:pathogenicity; D014777:Virus Diseases / Q000276:immunology*