[Evaluation of hemodynamic changes in patients with primary arterial hypertension after treatment with a combination of pindolol and clopamide (Viskaldix)].
In 35 patients with mild essential hypertension the influence of 9 week Viskaldix therapy on hemodynamics was evaluated. Twelve of them underwent repeated hemodynamic examinations after mean 13 months treatment. Viskaldix therapy lowered total peripheral resistance --TPR and there was no significant influence on the heart rate, stroke volume, and cardiac output. It was demonstrated that decrease of total peripheral resistance after treatment with Viskaldix was directly proportional to the initial values of TPR.
II Kliniki Chorób Wewnetrznych Instytutu Chorób Wewnetrznych Akademii Medycznej w Gdańsku.
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Wyrzykowski
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Suchecka-Rachoń
D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D003005:Clopamide / Q000008:administration & dosage* / Q000627:therapeutic use*; D004338:Drug Combinations; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010869:Pindolol / Q000008:administration & dosage* / Q000627:therapeutic use*
D000959:Antihypertensive Agents; D004338:Drug Combinations; C034039:clopamide, pindolol drug combination; D003005:Clopamide; D010869:Pindolol
Ocena zmian w dynamice krazenia u chorych z pierwotnym nadciśnieniem tetniczym po leczeniu trwałym połaczeniem pindololu z klopamidem (Viskaldix).