[Osmolality of contrast media--a risk factor in radiological endovascular procedures in children].
The study was conducted in 90 children aged from 5 months to 14 years during radiologically-guided endovascular (RIV) interventions with bolus injection of radiocontrast agents (RCA) in a dose of 2-3 ml/kg for 2-3 sec. High-osmolality RCA were used in 80 children, an nonionic low-osmolality RCA omnipaque-300 in 10 children. Injection of RCA bolus was attended by marked acute disorders of blood colloidoosmotic equilibrium (COE) which depended on the initial status of the latter and were greater when high osmolality RCA were used. On the basis of the study results, the authors developed and tested a method of modulator infusion therapy with consideration for the initial blood COE (hyper-, normo-, hypoosmolality). The suggested therapy makes it possible to reduce the degree of blood COE disorders considerably and prevent the development of complications associated with disturbed osmoregulation.
B A
BA
Mikhel'son
N D
ND
Guliev
V V
VV
Lazarev
Iu A
IuA
Poliaev
Iu A
IuA
Vodolazov
D000293:Adolescent; D000792:Angiography / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D003287:Contrast Media / Q000009:adverse effects*; D005440:Fluid Therapy; D006801:Humans; D007223:Infant; D009994:Osmolar Concentration; D012307:Risk Factors; D014883:Water-Electrolyte Imbalance / Q000139:chemically induced / Q000628:therapy*
D003287:Contrast Media
Osmolialnoct' rentgenokontrastnykh veshchestv--faktor agressii pri rentgenoendovackuliarnykh vmeshchatel'stvakh u deteĭ.