Virus-induced amyloidoses.
After a short introduction into the general concept of amyloidoses and the genetic disposition involved in these diseases, the genetic disposition for unconventional virus diseases (or transmissible spongiform encephalopathies) and the disease specific amyloid are described. Experimental studies on the pathogenesis and the infectious agent suggest that scrapie and related diseases are virus-induced amyloidoses of the brain.
Robert Koch-Institut, Berlin 65, Germany.
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Diringer
D000544:Alzheimer Disease / Q000473:pathology; D000686:Amyloidosis / Q000235:genetics / Q000382:microbiology*; D000818:Animals; D001927:Brain Diseases / Q000235:genetics / Q000382:microbiology*; D006801:Humans; D008954:Models, Biological; D012608:Scrapie / Q000382:microbiology / Q000473:pathology; D014777:Virus Diseases / Q000635:transmission