Some immunological correlations between thyroid pathology and ophthalmopathy.
Hormonal and immunogenetic investigation of patients with ophthalmopathy in the presence of thyroid pathology and without it made it possible to come to a conclusion of the independence of both diseases. Immunological markers of thyroid pathology in the presence of ophthalmopathy are noted less frequently than in thyroid diseases without ophthalmopathy. The latter is characterized by the presence of specific autoantibodies to eye muscle membranes in the patients' sera. The presence of antithyroid antibodies increases the probability of appearance of antibodies to eye muscles and therefore can be regarded as a risk factor of ophthalmopathy.
Laboratory of Pathophysiology, USSR Academy of Medical Sciences, Moscow.
V
V
Kandror
M
M
Birjukova
I
I
Kryukova
N
N
Mkrtumova
E
E
Konnova
D000328:Adult; D000368:Aged; D001323:Autoantibodies / Q000276:immunology; D005128:Eye Diseases / Q000150:complications* / Q000276:immunology; D006680:HLA Antigens / Q000032:analysis; D006801:Humans; D008875:Middle Aged; D009801:Oculomotor Muscles / Q000276:immunology; D013959:Thyroid Diseases / Q000150:complications* / Q000276:immunology; D013961:Thyroid Gland / Q000276:immunology / Q000473:pathology
D001323:Autoantibodies; D006680:HLA Antigens