Plant metabolites. New compounds and anti-inflammatory activity of Uncaria tomentosa.
Bioassay-directed fractionation of the anti-inflammatory extracts of Uncaria tomentosa, using the carrageenan-induced edema in rat paw, has led to the isolation of a new quinovic acid glycoside 7 as one of the active principles. Furthermore, a new triterpene 8 was isolated as its methyl ester. The structures were elucidated by spectral and chemical studies.
Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli Federico II, Italy.
R
R
Aquino
V
V
De Feo
F
F
De Simone
C
C
Pizza
G
G
Cirino
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D015394:Molecular Structure; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D011919:Rats, Inbred Strains; D014315:Triterpenes / Q000302:isolation & purification / Q000494:pharmacology
D000894:Anti-Inflammatory Agents, Non-Steroidal; D014315:Triterpenes