Side effects of erythropoietin therapy.
Recombinant erythropoietin is usually associated with marked improvement in physiological and psychological well-being. Adverse effects are unusual. In this report, the unusual occurrence of seizures, increased clotting, and influenza-like syndromes is reviewed. Emphasis is given to adverse effects noted in the few available placebo-controlled studies.
Department of Medicine, Oregon Health Sciences University, Portland 97201.
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Bennett
D000740:Anemia / Q000209:etiology / Q000628:therapy*; D001778:Blood Coagulation Disorders / Q000209:etiology; D002986:Clinical Trials as Topic; D004921:Erythropoietin / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D011994:Recombinant Proteins / Q000009:adverse effects / Q000627:therapeutic use; D012640:Seizures / Q000209:etiology
D011994:Recombinant Proteins; D004921:Erythropoietin