Case report: fatal pulmonary toxoplasmosis following chemotherapy.
A 41-year-old woman with acute myelomonocytic leukemia in remission died of a rapidly progressive necrotizing pneumonia while in the recovery phase following consolidation chemotherapy. Autopsy revealed disseminated toxoplasmosis. Although this syndrome has been well described to present as a neurologic complication in certain immunocompromised patients, it is rare in acute leukemia, and non-neurologic presentations are even more unusual. This case emphasizes the need to be suspicious of toxoplasmosis in immunocompromised patients even in the absence of neurologic signs or symptoms.
Brown
N J
NJ
Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232.
McKenzie
S
S
Decker
M D
MD
D000328:Adult; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D015479:Leukemia, Myelomonocytic, Acute / Q000188:drug therapy*; D008174:Lung Diseases, Parasitic / Q000209:etiology*; D014123:Toxoplasmosis / Q000209:etiology*