Unusual t(3;12)(q28;q13) in childhood acute lymphoblastic leukemia.
In this article we report a case of a 7-year-old boy affected by acute lymphoblastic leukemia of the common type. Bone marrow examination at diagnosis showed a reciprocal translocation between the long arm of chromosome 3 and the long arm of chromosome 12. This previously unpublished translocation is discussed and compared to the findings in the current literature.
Blood Bank Service, Ospedale Bambino, Gesu, Rome.
A
A
Angioni
F
F
Ghione
C
C
Miano
D
D
Rosati
C
C
Guazzelli
P
P
Balloni
C
C
Mecucci
D002648:Child; D002881:Chromosomes, Human, Pair 12; D002893:Chromosomes, Human, Pair 3; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics*; D014178:Translocation, Genetic