Involvement of chromosome 13 in myelodysplastic syndromes.
We report 2 of 80 cases of myelodysplastic syndromes (MDS) cytogenetically studied, with involvement of chromosome 13. The first case had a t(6;13), and the second had a t(1;13). Abnormalities of chromosome 13 mainly involving loss of band 13q14 have been described in hematologic malignancies. In both our cases band 13q14 did not participate in the deleted segment.
Panani
A D
AD
Second Department of Internal Medicine, Propaedeutic of Athens University, Evangelismos Hospital, Greece.
Ferti-Passantonopoulou
A
A
Pappa
V
V
Dervenoulas
J
J
Raptis
S
S
D000368:Aged; D002878:Chromosomes, Human, Pair 1; D002882:Chromosomes, Human, Pair 13; D002896:Chromosomes, Human, Pair 6; D005260:Female; D006801:Humans; D007621:Karyotyping; D009190:Myelodysplastic Syndromes / Q000235:genetics*; D014178:Translocation, Genetic