[Pepsin activity of the stomach as a pathogenetic factor of duodenal ulcer and prognostic indicator of its course].
Proteolytic activity in the stomach can play an active role in pathogenesis of duodenal ulcer (DU). When high, this activity attends a severe course of the disease. It is feasible to prognosticate DU progress in remission patients basing on gastric pepsin levels. Normal gastric pepsin levels suggest a favorable long-term outcome. In DU aggravation investigations of acid-peptic aggression should be supplemented by examination of the mucous protective barrier.
Iu Ia
IuIa
Shmykov
D000208:Acute Disease; D002940:Circadian Rhythm / Q000502:physiology; D004381:Duodenal Ulcer / Q000209:etiology / Q000503:physiopathology*; D005744:Gastric Acid / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism*; D006801:Humans; D010434:Pepsin A / Q000378:metabolism*; D011379:Prognosis; D012008:Recurrence; D012720:Severity of Illness Index
D010434:Pepsin A
Pepsinovaia aktivnost' zheludka kak faktor patogeneza iazvennoĭ bolezni dvenadtsatiperstnoĭ kishki i prognosticheskiĭ pokazatel' techeniia zabolevaniia.