[Ulcerous disease of endocrinal origin caused by a non-gastric substance].
The purpose of this paper is to report on a form of duodenal ulceration associated with a major hypersecretion that we described in 1984. This entity belongs to the group of endocrine duodenal ulcer diatheses of which the Zollinger-Ellison Syndrome (ZES) is the prototype. We have recently in 1989 reported a series of patients with clinical and pathologic features indistinguishable from those of the Zollinger-Ellison syndrome but without hypergastrinemia. We have also found that the plasma and the tumor tissues of these patients contains a potent non-gastrin secretagogue.
Service de Chirurgie Générale, Université de Rochester, New York 14607.
R
R
Menguy
W Y
WY
Chey
D000328:Adult; D000368:Aged; D005260:Female; D005745:Gastric Acidity Determination; D005750:Gastric Juice / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015043:Zollinger-Ellison Syndrome / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology*
Maladie ulcéreuse d'origine endocrine véhiculée par une substance non-gastrinique.