Renal trapping of In-111 troponolate labeled platelets in thrombotic thrombocytopenic purpura.
A patient with active thrombotic thrombocytopenic purpura underwent examination with In-111 troponolate labeled autologous platelets. A mean platelet survival of 1.2 days was found, comparable to formerly described studies using other methods. Furthermore, remarkable renal uptake of radioactivity consistent with abnormal platelet trapping was demonstrated. In the absence of any other signs of renal involvement, the conclusion was reached that the platelet scan is a sensitive and direct method for showing renal involvement in thrombotic thrombocytopenic purpura.
Department of Internal Medicine, Stichting Deventer Hospital, The Netherlands.
E J
EJ
Kuipers
T M
TM
Brouwers
H J
HJ
Hazenberg
D000293:Adolescent; D001792:Blood Platelets; D005260:Female; D006801:Humans; D007205:Indium Radioisotopes; D007668:Kidney / Q000000981:diagnostic imaging*; D009942:Organometallic Compounds; D011697:Purpura, Thrombotic Thrombocytopenic / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D014334:Tropolone / Q000031:analogs & derivatives
D007205:Indium Radioisotopes; D009942:Organometallic Compounds; C043895:indium tris(tropolonate); D014334:Tropolone