Extrapituitary acromegaly.
Acromegaly may result from ectopic production of the hypothalamic peptide, growth hormone releasing hormone (GHRH), or growth hormone (GH) itself. Hypothalamic, carcinoid, and pancreatic tumors account for most of these cases. The pathogenesis, etiology, and diagnosis of acromegaly caused by these nonpituitary tumors is discussed, and an approach to their management is provided.
Division of Endocrinology and Metabolism, Cedars-Sinai Medical Center, Los Angeles, California.
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D000172:Acromegaly / Q000175:diagnosis / Q000503:physiopathology*; D003937:Diagnosis, Differential; D013006:Growth Hormone / Q000378:metabolism; D013007:Growth Hormone-Releasing Hormone / Q000378:metabolism; D006729:Hormones, Ectopic / Q000378:metabolism; D006801:Humans; D007031:Hypothalamus / Q000378:metabolism; D009384:Paraneoplastic Endocrine Syndromes / Q000175:diagnosis / Q000503:physiopathology
D006729:Hormones, Ectopic; D013006:Growth Hormone; D013007:Growth Hormone-Releasing Hormone