Prognosis of fetuses with a cystic hygroma.
This paper reports our experience with 55 fetuses identified in utero to have a cystic hygroma. The outcome of fetuses with an isolated cystic hygroma, cystic hygroma with non-immune hydrops, and cystic hygroma with multiple anomalies was evaluated. Approximately two-thirds of karyotypes were aneuploid, and a strong association of septation and aneuploidy existed. Only five cases, four of which had isolated hygromas, came to term and resulted in live births. Two of these involved small non-septated lesions which resolved in utero.
Department of Obstetrics, University of California, San Francisco.
H S
HS
Bernstein
R A
RA
Filly
J D
JD
Goldberg
M S
MS
Golbus
D000293:Adolescent; D000328:Adult; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000235:genetics / Q000401:mortality*; D006801:Humans; D007621:Karyotyping; D008202:Lymphangioma / Q000000981:diagnostic imaging / Q000235:genetics / Q000401:mortality*; D008875:Middle Aged; D011247:Pregnancy; D011296:Prenatal Diagnosis; D011379:Prognosis; D012189:Retrospective Studies; D014463:Ultrasonography