Serial MR imaging in Creutzfeldt-Jakob disease.
Serial magnetic resonance (MR) imagings of two autopsied patients with Creutzfeldt-Jakob disease (CJD) are presented. Both patients showed a dramatic progression of brain atrophy. The initial MR imagings were, however, interpreted as normal except for localized mild cortical atrophy in one patient. When a normal MR image is obtained in a demented middle-aged or aged patient, CJD may still need to be ruled out: follow up MR imaging may be useful.
Uchino
A
A
Department of Radiology, Kyushu Rosai Hospital, Kitakyushu, Japan.
Yoshinaga
M
M
Shiokawa
O
O
Hata
H
H
Ohno
M
M
D000368:Aged; D001921:Brain / Q000473:pathology*; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged