[Effect of duokang jiasu on the cytotoxicity of peripheral blood mononuclear cells].
Duokang Jiasu, a biological reaction modifier widely used in cancer clinics, has been proved that its tumor suppression effect is based on the macrophage activity. The results of this study showed that monocytes treated with Duokang jiasu in vitro has much stronger cytotoxicity against allogenic tumor cells. Incubation of mononuclear cells with Duokang jiasu beforehand could promote both NK and ADCC activities.
Department of Pathology, Xian Medical University.
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D000276:Adjuvants, Immunologic / Q000494:pharmacology*; D000920:Antibody-Dependent Cell Cytotoxicity / Q000187:drug effects*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D006801:Humans; D007694:Killer Cells, Natural / Q000187:drug effects; D007963:Leukocytes, Mononuclear / Q000187:drug effects*; D014407:Tumor Cells, Cultured / Q000187:drug effects
D000276:Adjuvants, Immunologic; D004365:Drugs, Chinese Herbal; C059907:duokangjiasu