[The determination and evaluation of the plasma amino acid in respiratory failure].
The measurement of the plasma amino acid was made in 15 patients with chronic respiratory failure and 15 persons of control. The results showed: (1) The plasma acid model changed. Lysine increases and arginine decreases, due to hypothermia. Hypercapnia imbalance of acid and alkali and changes of hepatic dysfunction etc. (2) The prognosis of respiratory failure as well as its severity was judged according to the decreasing extent of arginine and BCAA. The more worse the condition of the disease, the more lowering of the level of arginine and BCAA. (3) The changes of blood gas analysis and hepatic dysfunction may effect on the metabolism of plasma amino acid in some degree. (4) Hypoxemia in infected patients with respiratory failure may cause peripheral deficit of energy. We suggested that patients should be given BCAA and arginine for more energy as anti-infection and oxygen therapy were used.
Research Section of Respiratory Disease, Second Hospital Attached to Sheng Yang Medical College.
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Pan
D000328:Adult; D000368:Aged; D000596:Amino Acids / Q000097:blood*; D000597:Amino Acids, Branched-Chain / Q000097:blood; D001120:Arginine / Q000097:blood; D005260:Female; D006801:Humans; D008239:Lysine / Q000097:blood; D008297:Male; D008875:Middle Aged; D012131:Respiratory Insufficiency / Q000097:blood*
D000596:Amino Acids; D000597:Amino Acids, Branched-Chain; D001120:Arginine; D008239:Lysine