Multiple sclerosis in childhood. Longitudinal study in 14 cases.
The Authors review the literature on the occurrence of multiple sclerosis in children and add 14 personal cases below the age of 15.5 years, the youngest being 6.4 years old. Modality of onset, clinical course, clinical classification according to the criteria proposed by McDonald and Halliday, paraclinical evidence of lesions and disability grade at the last control are widely discussed. Eleven cases were scheduled as clinically definite multiple sclerosis. In the youngest children the recovery may be often complete or the disability grade may be low.
Neurological Clinic, Child Neuropsychiatric Service, University of Bari, Italy.
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Perniola
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Russo
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Margari
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Buttiglione
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Simone
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009103:Multiple Sclerosis / Q000453:epidemiology* / Q000503:physiopathology / Q000628:therapy