[The effect of serotonin on the heart contraction frequency in the suslik Citellus undulatus depends on the environmental temperature].
In experiments on active ground squirrels, it has been shown that the effect of intraperitoneal injection of serotonin on the heart rate depends on the dose and the environmental temperature. At relatively low doses and high environmental temperature, serotonin increases the heart rate and body temperature; on the contrary, with the increase in the dosage and the decrease in the environmental temperature the heart rate and body temperature of animals decrease. It is suggested that this relationship serves as one of the factors which enhance the transition of animals from one level of activity to another during the beginning and the end of hibernation.
D A
DA
Ignat'ev
G S
GS
Sukhova
V P
VP
Sukhov
D000818:Animals; D001831:Body Temperature / Q000187:drug effects / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D006339:Heart Rate / Q000187:drug effects* / Q000502:physiology; D006605:Hibernation / Q000187:drug effects / Q000502:physiology; D012589:Sciuridae / Q000502:physiology*; D012701:Serotonin / Q000494:pharmacology*; D013696:Temperature; D014159:Transducers; D014851:Wakefulness / Q000187:drug effects / Q000502:physiology
D012701:Serotonin
Vliianie serotonina na chastotu serdechnykh sokrashcheniĭ suslika Citellus undulatus zavisit ot temperatury sredy.