[Application of positive end expiratory pressure (PEEP) and continuous positive airway pressure (CPAP) in the treatment of asthma].
Two intubated young adults with respiratory failure and acidosis due to severe asthma attack were treated by mechanical ventilation with PEEP. Two hours after using of PEEP the expiratory resistance decreased from 35 to 14 cmH2O/L/Sec and 56 to 18 cmH2O/L/Sec respectively, and within two days they were successfully weaned from mechanical ventilation. Another fifteen patients with moderate asthmatic attack were treated with CPAP via a mask from Siemens 900C ventilator. Twenty minutes later the FEV1 and VC were significantly increased from 1.19 +/- 0.69 L to 1.36 +/- 0.73 L and 2.41 +/- 0.97 to 2.65 +/- 0.94 L respectively. We concluded that, PEEP and CPAP have mechanical bronchodilative effect on spasm bronchi, and could be used as a effective way to treat severe asthma attack.
Liu
Y N
YN
Chinese PLA General Hospital, Beijing.
D000142:Acidosis, Respiratory / Q000209:etiology / Q000628:therapy; D000328:Adult; D001249:Asthma / Q000150:complications / Q000628:therapy*; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D008875:Middle Aged; D011175:Positive-Pressure Respiration / Q000379:methods; D012131:Respiratory Insufficiency / Q000209:etiology / Q000628:therapy