Porous phase model of the lung interstitial fluid motion.
A mathematical model of nonsteady-state fluid movement in the lung interstitium during hydrodynamic loading is evaluated. The model is based on experimental results obtained in isolated perfused canine lungs. The interstitium is treated as a porous phase with an elastic framework, able to relax; all resistance to flux is in the interstitial tissue and not in the endothelium. A numerical iteration procedure was applied for the calculation of fluid transfer coefficients. The model describes space distribution of driving pressures in the interstitium.
Laboratory of Medical Research and Technology, Association Alpha, Leningrad, USSR.
V B
VB
Serikov
D000818:Animals; D001783:Blood Flow Velocity; D002199:Capillary Permeability; D002200:Capillary Resistance; D004285:Dogs; D005260:Female; D008168:Lung / Q000098:blood supply / Q000502:physiology*; D008196:Lymph / Q000502:physiology*; D008297:Male; D008433:Mathematics; D008954:Models, Biological; D009997:Osmotic Pressure; D010477:Perfusion / Q000295:instrumentation / Q000379:methods