[What is the role of nutrition in Crohn disease? A contribution to the importance of dietary therapy in regional enteritis].
The clinical appearance of Crohn's disease (CD) is especially marked by nutritional deficits and insufficiencies. For a long time the goal of nutritional care was reduced to the readjustment of the nutritional status. The development and clinical use of controlled parenteral nutrition (TPN) and enteral nutritive solutions (EN) did not only emphasize this therapeutical issue, but furthermore showed positive effects on the conservative as well as on the surgical treatment concepts. Therefore today artificial nutritional support is a firm part of therapy in acute, active phases or in the contact of surgical management of CD. This is especially valid in children, where complications in general and growth failure in particular can be reduced. EN is the preferred feeding method in most of the cases, due to a lower complication rate and reduced cost when compared to TPN. The question regarding the importance of nutritional support as primary therapy has also been investigated. The results differ extensively, but point towards the conclusion that patients with solitary small bowel disease do profit from this therapeutical concept. Nevertheless it is unclear, how TPN or EN interfere in the pathophysiology or -biochemistry in this process. A question about reduction e.g. of allergic components of daily diet did stimulate new theories regarding the hypothesis of a possible causal relationship between diet and the pathogenesis of CD. Investigations on dietary habits and daily dietary therapy did not reveal an overall accepted dietary guideline. Nevertheless it seems obvious that dietary counselling has a positive effect on the disease process. It does appear, that today in the acute, active phase as well as in the long term management of Crohn's disease nutritional-care is an important therapeutical method.
Klinik für Abdominal- und Transplantationschirurgie, Medizinische Hochschule, Hannover, BRD.
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Nagel
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Canzler
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Pichlmayr
D003424:Crohn Disease / Q000209:etiology / Q000628:therapy*; D004750:Enteral Nutrition / Q000379:methods*; D005247:Feeding Behavior; D005500:Follow-Up Studies; D006801:Humans; D010289:Parenteral Nutrition, Total / Q000379:methods*; D012307:Risk Factors
Welche Rolle spielt die Ernährung beim Morbus Crohn? Ein Beitrag zur Bedeutung der diätetischen Therapie der Enteritis regionalis.