Role of bronchoalveolar lavage in diagnosis of disseminated toxoplasmosis.
In three cases of acute disseminated toxoplasmosis developing soon after renal (two patients) or hepatorenal (one patient) transplantation, Toxoplasma gondii trophozoites were visualized on Giemsa-stained smears of bronchoalveolar lavage fluid. Trophozoites were also found in bone marrow smears in one instance. Seroconversion occurred late in two cases and was not detected before the patient's death in the third. These observations underline the potential of bronchoalveolar lavage as a diagnostic procedure for disseminated toxoplasmosis.
Department of Infectious Diseases, Cliniques Universitaires de Bruxelles, Hôpital Erasme, Belgium.
F
F
Jacobs
M
M
Depierreux
M
M
Goldman
M
M
Hall
C
C
Liesnard
F
F
Janssen
C
C
Toussaint
J P
JP
Thys
D000293:Adolescent; D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D001992:Bronchoalveolar Lavage Fluid / Q000469:parasitology*; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D016031:Liver Transplantation; D008297:Male; D012189:Retrospective Studies; D014122:Toxoplasma / Q000276:immunology / Q000302:isolation & purification*; D014123:Toxoplasmosis / Q000175:diagnosis* / Q000209:etiology
D000913:Antibodies, Protozoan