[The value of classification for therapy and prognosis of acute pancreatitis. Analysis of a patient sample of the Heidelberg Surgical University Clinic 1986-1989].
116 patients admitted for acute pancreatitis were analysed. In 80% of patients presenting biliary pancreatitis cholecystectomy and bile duct exploration was the prevalent treatment, in 7.8% pancreatic necrosis was removed. Indications to operate on patients with non-biliary pancreatitis included enhancement of pancreatic inflammation revealed by computed tomography and multi-organ-failure or sepsis complicating the course of the disease (incidence of laparotomy 20.3%, incidence of necrosectomy 12.3%). According to this concept 2 out of 3 patients presenting partial pancreatic necrosis recovered without operation. Lethality of patients with acute necrotizing pancreatitis (6.9%) was accounted 25%, over-all mortality 6%. Methods used for classification of severity of acute pancreatitis (Mainz classification, Ranson criteria) turned out to be not reliable. Clinical staging of pancreatitis was not in accordance with intraoperative findings in 51.9% of cases. As a prerequisite for stage-dependent therapy new objective data to access severity and clinical course of acute pancreatitis have to be worked out.
Foitzik
T
T
Chirurgische Universitätsklinik, Heidelberg.
Klar
E
E
Runkel
N
N
Buhr
H J
HJ
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000150:complications; D002423:Cause of Death; D002769:Cholelithiasis / Q000150:complications / Q000601:surgery; D005260:Female; D005858:Germany; D006801:Humans; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy; D010186:Pancreatic Function Tests; D010195:Pancreatitis / Q000145:classification / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D011183:Postoperative Complications / Q000401:mortality*; D011446:Prospective Studies; D012307:Risk Factors; D015996:Survival Rate
Stellenwert der Klassifikation für die Therapie und Prognose der akuten Pankreatitis. Analyse des Krankengutes der Chirurgischen Universitätsklinik Heidelberg 1986-1989.