[A case of infiltrative transitional cell carcinoma of the kidney with hypercalcemia].
A 73-year-old man was admitted to our hospital with chief complaint of macrohematuria. Computerized tomography revealed enlargement of right kidney, tumor thrombi and lymph nodal involvement. Distant metastases were found in liver, lung and pelvis. We performed conservative therapy including right renal embolization. However, serum calcium levels continued to increase. Patient died from renal failure and pneumonia after 2 months, and autopsy was performed. Histological examination revealed infiltrative transitional cell carcinoma of the right kidney. PTH like peptide was measured 1 ng/gram wet tissue from the primary tumor and 16.6 ng/gram wet tissue from the metastatic liver tumor.
Department of Urology, Asahi General Hospital.
M
M
Tanaka
T
T
Oki
S
S
Hara
T
T
Igarashi
S
S
Murakami
O
O
Matsuzaki
K
K
Nagao
T
T
Yasuda
D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D002295:Carcinoma, Transitional Cell / Q000150:complications* / Q000473:pathology; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D007680:Kidney Neoplasms / Q000150:complications* / Q000473:pathology; D008297:Male; D044162:Parathyroid Hormone-Related Protein; D011506:Proteins / Q000032:analysis
D014408:Biomarkers, Tumor; C470121:PTHLH protein, human; D044162:Parathyroid Hormone-Related Protein; D011506:Proteins