[The successive presence of acute lymphoblastic leukemia, Hodgkin's disease and acute myeloblastic leukemia in a female patient].
A case is presented of a female patient initially diagnosed of acute lymphoblastic leukemia who was treated achieving complete remission. Twenty six months later and while in remission of her leukemia, she presented an abdominal mass the histological study of which showed infiltration due to Hodgkin disease. She was treated with chemotherapy type MOPP and complete remission was achieved. Four months after completing treatment she presented pancytopenia in peripheral blood. A bone marrow study was performed observing a blastoid infiltration with morphological and cytochemical characteristics of acute non-lymphoblastic M-5 leukemia. The possible common origin of the three clinical pictures is discussed given the recent findings regarding the origin of Reed-Sternberg cell.
Servicio de Hematología, Hospital Universitario San Carlos, Madrid.
E
E
del Potro
G
G
Espinola Guedes
R
R
Martínez
A
A
Alvarez
J
J
Díaz Mediavilla
C
C
Martín
A
A
Villegas
D
D
Espinós
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D005260:Female; D006689:Hodgkin Disease / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis* / Q000188:drug therapy; D016609:Neoplasms, Second Primary; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000188:drug therapy; D012074:Remission Induction; D013997:Time Factors
Presencia sucesiva de leucemia aguda linfoblástica, enfermedad de Hodgkin y leucemia aguda mieloblástica en una enferma.