[Histo- and ultrahisto-pathology of the anterior chamber angle in congenital glaucoma].
92 trabeculectomy specimens of congenital glaucoma, aged 35 days to 46 years, were studied by light and transmission electron microscopy, with findings of narrowed anterior chamber angle, thickened ciliary muscle displaced forward, and crooked or thickened trabeculae, many disintegrated with hyaloid degeneration. The cribriform meshwork appeared dense, with deposition of fibrillae and collagen or basement membrane-like material; Schlemm's canal was absent in 3 specimens; in some the lumen was narrowed or locally obliterated; and Descemet membrane-like substance covered the trabecular meshwork. The types of pathological changes, their relationship with the symptoms, and the locations of outflow resistance were discussed.
Zhongshan Ophthalmic Centre, Sun Yat-sen University of Medical Sciences, Guangzhou.
J
J
Zhang
D000293:Adolescent; D000328:Adult; D000867:Anterior Chamber / Q000473:pathology / Q000648:ultrastructure*; D001082:Aqueous Humor / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D005260:Female; D005901:Glaucoma / Q000151:congenital / Q000473:pathology*; D006801:Humans; D007223:Infant; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D014129:Trabecular Meshwork / Q000473:pathology / Q000648:ultrastructure*