Changes in muscle fiber size and composition in response to heavy-resistance exercise.
Progressive resistance exercise was used to induce hypertrophy in the right palmaris longus muscle (PLM) of 16 cats. The left PLM served as the non-exercised intra-animal control. After an average 150 +/- 26.6 wk of training, left and right PLMs were removed and weighed. Muscle fibers were typed using standard histochemical techniques. Mean fiber cross-sectional area, connective tissue content, and muscle fiber length were determined. The right exercised PLM demonstrated a 24.2 +/- 6.9% increase in muscle mass. Mean muscle fiber cross-sectional area increased 11.0 +/- 7.3% in the exercised muscles. No change in connective tissue content, fiber length, or fiber type composition was observed. The results show that increases in muscle fiber cross-sectional area do not account for all the observed increases in muscle mass, and that other mechanisms, such as muscle fiber hyperplasia, may play a role in contributing to muscle mass increases.
Department of Cell Biology and Neuroscience, University of Texas Southwestern Medical Center, Dallas 75235-9039.
A E
AE
Mikesky
C J
CJ
Giddings
W
W
Matthews
W J
WJ
Gonyea
D000818:Animals; D002415:Cats; D006965:Hyperplasia; D006984:Hypertrophy; D009132:Muscles / Q000033:anatomy & histology* / Q000473:pathology; D010805:Physical Conditioning, Animal; D014891:Weight Lifting