The treatable dementia of Sjögren's syndrome.
Progressive dementia developed during a 15-month period in a 56-year-old woman with serologically and clinically documented primary Sjögren's syndrome. Findings from magnetic resonance imaging and angiography were normal, but a brain biopsy disclosed perivascular lymphocytic inflammation in leptomeningeal and parenchymal vessels. Treatment with high-dose corticosteroids produced rapid and nearly complete resolution of the dementia.
Caselli
R J
RJ
Department of Neurology, Mayo Clinic, Rochester, MN.
Scheithauer
B W
BW
Bowles
C A
CA
Trenerry
M R
MR
Meyer
F B
FB
Smigielski
J S
JS
Rodriguez
M
M
D000544:Alzheimer Disease / Q000175:diagnosis; D003704:Dementia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D003951:Diagnostic Errors; D005260:Female; D006212:Hallucinations / Q000188:drug therapy / Q000209:etiology; D006801:Humans; D008590:Meningoencephalitis / Q000188:drug therapy / Q000209:etiology*; D008875:Middle Aged; D010258:Paranoid Behavior / Q000188:drug therapy / Q000209:etiology; D011241:Prednisone / Q000627:therapeutic use*; D011581:Psychological Tests; D012859:Sjogren's Syndrome / Q000150:complications* / Q000188:drug therapy
D011241:Prednisone