Hormonal patterns in a successful pregnancy of a patient with late-onset 21-OH deficiency taking methylprednisolone; a case report.
A successful pregnancy of a young woman with late-onset congenital adrenal hyperplasia (LOCAH) is reported. Exogenous glucocorticoids are the most commonly used regimen in such cases both for suppression of adrenal overstimulation and avoiding masculinization of a female fetus. In our LOCAH patient methylprednisolone has been used for treatment. We present the management and the outcome of this pregnancy, as well as the hormonal follow-up.
Phocas
I
I
2nd Department of Obstetrics and Gynecology, University of Athens, Areteion University Hospital, Greece.
Sarandakou
A
A
Rizos
D
D
Chryssikopoulos
A
A
D019326:17-alpha-Hydroxyprogesterone; D000312:Adrenal Hyperplasia, Congenital / Q000188:drug therapy* / Q000503:physiopathology; D000328:Adult; D000653:Amniotic Fluid / Q000737:chemistry; D005260:Female; D005640:Follicle Stimulating Hormone / Q000032:analysis; D006801:Humans; D006908:Hydroxyprogesterones / Q000032:analysis; D007986:Luteinizing Hormone / Q000032:analysis; D008775:Methylprednisolone / Q000627:therapeutic use*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy* / Q000503:physiopathology; D011388:Prolactin / Q000032:analysis; D013963:Thyroid Hormones / Q000032:analysis
D006908:Hydroxyprogesterones; D013963:Thyroid Hormones; D019326:17-alpha-Hydroxyprogesterone; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D008775:Methylprednisolone