The conformation of echinomycin in DMSO solution.
The conformation of the antibiotic echinomycin in DMSO solution has been determined from two-dimensional NMR and distance geometry calculation with distance constraints. Five converged conformations were calculated with NOE distance constraints followed by restraint energy minimization.
Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan, Republic of China.
C
C
Yu
T H
TH
Yang
J J
JJ
Young
D004121:Dimethyl Sulfoxide; D004448:Echinomycin / Q000737:chemistry*; D004735:Energy Transfer; D009682:Magnetic Resonance Spectroscopy; D011487:Protein Conformation / Q000187:drug effects; D012996:Solutions; D013237:Stereoisomerism
D012996:Solutions; D004448:Echinomycin; D004121:Dimethyl Sulfoxide