Movement disorder with abnormal copper metabolism--a case report and review of the literature.
We describe a neurological disease, seen in the elder sister of identical twins, with dysarthria, involuntary movements, spastic gait, slightly low serum copper, borderline low to normal serum ceruloplasmin, normal urinary copper, and a high hair copper concentration. This neurological disorder appears to differ from others associated with abnormal copper metabolism such as Wilson's or Menkes' kinky hair disease.
Third Department of Internal Medicine, Kyoto Prefectural University of Medicine, Japan.
K
K
Araki
I
I
Tachibana
Y
Y
Ueda
K
K
Kashima
D000328:Adult; D003300:Copper / Q000378:metabolism*; D004200:Diseases in Twins; D005260:Female; D006801:Humans; D009069:Movement Disorders / Q000209:etiology / Q000235:genetics / Q000378:metabolism*; D014430:Twins, Monozygotic
D003300:Copper