[Family studies on the incidence of multiple pigmented naevi, familial skin melanoma and other malignant tumors].
102 family members of 14 patients with primary melanoma and multiple atypical pigmented naevi were investigated. Additionally to 14 patients with melanoma, 31 family members were found to have multiple atypical pigmented naevi. Most of them had light complexion and poor pigmentation capacity. A relative high frequency of malignant tumors other than melanoma were observed among blood relatives without multiple naevi. Members of melanoma-prone families need regular medical surveillance.
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Szent-Györgyi Albert Orvostudományi Egyetem, Szeged.
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D000328:Adult; D004416:Dysplastic Nevus Syndrome / Q000453:epidemiology / Q000235:genetics; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D015994:Incidence; D008297:Male; D008545:Melanoma / Q000453:epidemiology / Q000235:genetics*; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology / Q000235:genetics*; D009508:Nevus, Pigmented / Q000453:epidemiology / Q000235:genetics*; D010375:Pedigree; D010641:Phenotype; D011159:Population Surveillance; D012878:Skin Neoplasms / Q000453:epidemiology / Q000235:genetics*; D009626:Terminology as Topic
Családvizsgálatok többszörös festékes anyajegyek, familiáris börmelanoma és egyéb malignus tumorok elöfordulására vonatkozóan.