Cerebrospinal fluid concentration of fibronectin in meningitis.
Fibronectin concentrations in the cerebrospinal fluid were assessed in 20 patients with acute meningitis using a turbidimetric immunoassay. A significant increase in fibronectin concentrations was observed in patients with bacterial meningitis; decreased concentrations were observed in patients with viral meningitis. The determination of fibronectin concentration in patients with bacterial meningitis may represent a useful marker in differentiating bacterial from viral meningitis.
Division of Infectious Diseases, Regional Hospital, Varese, Italy.
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D000208:Acute Disease; D000328:Adult; D005260:Female; D005353:Fibronectins / Q000134:cerebrospinal fluid*; D006801:Humans; D007118:Immunoassay; D008297:Male; D008581:Meningitis / Q000134:cerebrospinal fluid*
D005353:Fibronectins