[Dynamics of rheological properties of the blood in patients with breast cancer during combined treatment].
The paper is devoted to the results of investigation of blood rheological features (dynamic blood and plasma viscosity) in 70 breast cancer patients during combined therapy. The basal levels of dynamic blood viscosity indices in these patients were lower by 11.6% than in the control group of healthy women (p less than 0.05). During combined therapy after a course of gamma-beam therapy (in the small fractionation regimen for the 1st group and large fractionation regimen for the 2nd group) a further decrease of blood and plasma viscosity indices was observed, reaching their minimum values on the 14th day after radical mastectomy. In a long-term period of combined therapy (5 years--the 3rd group) dynamic blood and plasma viscosity indices remained below the control values and had no significant differences from the basal values in the 1st and 2nd groups. These shifts in rheological blood features during combined therapy of breast cancer were probably of favourable nature as complications (hypostatic pneumonia, thromboses, necroses of displaces of skin grafts) in the postoperative period were absent.
Timchenko
V G
VG
Moroz
V A
VA
Shapovalov
S V
SV
D000328:Adult; D001809:Blood Viscosity; D001943:Breast Neoplasms / Q000097:blood* / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D015409:Mastectomy, Radical; D008875:Middle Aged; D011379:Prognosis; D011879:Radiotherapy Dosage; D013997:Time Factors
Dinamika reologicheskikh svoĭstv krovi bol'nykh rakom molochnoĭ zhelezy v protsesse kombinirovannogo lecheniia.