Early onset neonatal group B streptococcus (GBS) infection: associated obstetric risk factors.
An analysis of all early onset neonatal Group B streptococcal (GBS) infections at the Royal Women's Hospital, Melbourne was made for the 10-year period 1979-1988. There were 104 cases with 29 neonatal deaths (28%). One or more predisposing perinatal risk factors was evident in 82% of cases (premature labour 79%, prolonged membrane rupture (greater than 12 hours) 57%, premature rupture of the membranes 69%, maternal sepsis 29%). Overall, 88% of GBS infections were evident within 24 hours of birth, suggesting an intrapartum pathogenesis for infection.
Microbiology Department, Royal Women's Hospital, Melbourne, Victoria.
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Garland
D001437:Bacteriuria / Q000453:epidemiology / Q000209:etiology; D015984:Causality; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000453:epidemiology / Q000209:etiology; D006771:Hospitals, Maternity; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology / Q000276:immunology; D011272:Pregnancy, Multiple; D018805:Sepsis / Q000209:etiology; D013290:Streptococcal Infections / Q000453:epidemiology* / Q000209:etiology / Q000635:transmission; D013292:Streptococcus agalactiae; D014739:Victoria / Q000453:epidemiology