[Precancerous conditions in gastric cancer (II): relationship between atrophic gastritis-intestinal metaplasia-gastric dysplasia-gastric carcinoma].
We studied a group of gastric precancerous lesions in order to analyze their mutual relationship as well as and their association with the development of gastric carcinoma of the intestinal type. This study was performed on 850 gastric biopsy specimens. Our results demonstrate the strong association of atrophic gastritis, intestinal metaplasia and gastric dysplasia (p less than 0.001) which should be considered as precursor lesions of gastric cancer. Moreover, the relations between these lesions and the intestinal type of gastric carcinoma suggest their active participation in the genesis of this type of malignancy. Our results also suggest that chronic atrophic gastritis and intestinal metaplasia evolve to the dysplasia stage before developing gastric cancer.
Martínez Díaz
F J
FJ
Facultad de Medicina, Departamento de Anatomía Patológica, Universidad de Murcia.
Canteras Jordana
M
M
Ortuño Pacheco
G
G
D001706:Biopsy; D005757:Gastritis, Atrophic / Q000453:epidemiology / Q000473:pathology*; D006801:Humans; D007422:Intestines / Q000473:pathology*; D008679:Metaplasia; D011230:Precancerous Conditions / Q000453:epidemiology / Q000473:pathology*; D013270:Stomach / Q000473:pathology*; D013274:Stomach Neoplasms / Q000453:epidemiology / Q000473:pathology*
Lesiones precursoras del cáncer gástrico (II): Relación entre gastritis atrófica-metaplasia intestinal-displasia gástrica-carcinoma gástrico.