Recognition impairment correlated with short bisynchronous epileptic discharges.
The occurrence of transitory cognitive impairment during diffuse subclinical electroencephalographic (EEG) discharges has been widely documented but the role of the parameters influencing the cognitive performance and the involvement of motor or verbal response in the tasks used is still under debate. Fifteen patients suffering from primary generalized epilepsy with frequent bisynchronous EEG epileptic bursts underwent a shape recognition task during EEG monitoring. The test sequence was as follows: memorandum, pause, and multiple choice set. After pressing the response button, the patient was asked to confirm the choice verbally. The following parameters were considered: geometrical complexity of the shape, chronological position of the burst occurring during the single test, and the duration of discharge ranging from 1 to 3 s. Results showed a significant increase in incorrect responses during the test when discharges occurred, with more errors occurring for difficult than for easy shapes. Neither the discharge position nor the duration of the epileptic burst influenced the performance. Diffuse epileptic activity of short duration produced selective effects on the cognitive process regardless of the motor component of the response.
Provinciali
L
L
Institute of Nervous System Diseases, School of Medicine, University of Ancona, Italy.
Signorino
M
M
Censori
B
B
Ceravolo
G
G
Del Pesce
M
M
D000293:Adolescent; D000328:Adult; D001288:Attention / Q000502:physiology; D002648:Child; D002755:Choice Behavior / Q000502:physiology; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D004569:Electroencephalography; D004829:Epilepsy, Generalized / Q000150:complications / Q000503:physiopathology* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008570:Memory, Short-Term / Q000502:physiology; D010364:Pattern Recognition, Visual / Q000502:physiology; D013647:Task Performance and Analysis