[Comparative study of lymph node gangliosides and blood serum of normal and T-lymphotrophic baboons].
The gangliosides from the lymph nodes and blood sera of normal and T-lymphomic baboons were studied. In lymph nodes the major gangliosides were identified as GM3 and GD3, those in blood sera--as GM3, GM1 and GD3. Gangliosides GM3 and GD3 contained N-acetyl as well as N-glycoloyl neuraminic acids. In gangliosides isolated from lymph nodes and blood sera of T-lymphomic baboons the levels of N-glycoloyl neuraminic acid markedly exceeded that in normal tissues. In tumour lymph nodes the GM3/GD3 ratio was shifted towards GD3.
Malykh
Ia N
IaN
Diatlovitskaia
E V
EV
Lemenovskaia
A F
AF
Sorokin
M M
MM
Indzhiia
L V
LV
Iakovleva
L A
LA
Bergel'son
L D
LD
D000818:Animals; D002853:Chromatography, Liquid; D002855:Chromatography, Thin Layer; D005732:Gangliosides / Q000097:blood / Q000378:metabolism*; D008198:Lymph Nodes / Q000737:chemistry*; D016399:Lymphoma, T-Cell / Q000737:chemistry*; D010215:Papio; D012016:Reference Values
D005732:Gangliosides
Sravnitel'noe izuchenie gangliozidov limfaticheskikh uzlov i syvorotki krovi pavianov-gamadrilov v norme i pri T-kletochnykh limfomakh.