Simultaneous determination of carbamazepine and its major metabolites in human plasma and urine by HPLC.
A method is described for the analysis of carbamazepine and its major metabolites in biological fluids. The method uses a HPLC system based on a C18 Partisil column. The metabolites were extracted from chloroform in the presence of an internal standard. The method was specific, precise and reproducible.
Chelsea Department of Pharmacy, King's College London, U.K.
C K
CK
Tsaprounis
M
M
Kajbaf
J W
JW
Gorrod
D002220:Carbamazepine / Q000032:analysis* / Q000097:blood / Q000652:urine; D002851:Chromatography, High Pressure Liquid; D006801:Humans
D002220:Carbamazepine