Dupuytren's disease among the Chinese in Taiwan.
A retrospective study was made of 41 cases of Dupuytren's disease observed from 1970 to 1988 at the Veterans General Hospital-Taipei, Taiwan. The patients' ages ranged from 49 to 78 years; 21 patients had only one hand involved; 20 patients showed bilateral involvement. Thirty-three of 35 diseased hands with contracture were treated by regional fasciectomy. A follow-up study was done in 32 hands. The operative results of 30 hands were rated as good (94%); 3 showed extension of the disease and 1 had evidence of recurrence. Treatment was not given to 26 hands without contracture; 14 of these showed no change in the lesions, 3 improved, and 6 were worse when seen on subsequent visits. Seventeen of 33 excised thickened palmar fasciae contained nodules. All histological sections of nodule-free specimens showed dense connective tissues. Based on the fibroblastic activity and the amount of collagen, three easily discernible features of the histological make-up of the nodules were found.
Liu
Y
Y
Department of Orthopedics, Veterans General Hospital-Taipei, Taiwan, the Republic of China.
Chen
W Y
WY
D000368:Aged; D004387:Dupuytren Contracture / Q000208:ethnology* / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006225:Hand / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies; D013624:Taiwan / Q000453:epidemiology