Effectiveness of genetic counselling. Retinoblastoma.
The authors studied 32 families with 36 RB patients. Among them 24 were sporadic cases; four had recurrence of RB; two had RB plus bone tumour in relatives and two were RB propositi. Two evaluations with an interval from four to 13 years were made. In the first the recurrence risk was informed as high or low. The patients' decisions were evaluated at the second consultation. The authors considered that counselling was negative in more than 50% of cases. For normal parents, prognosis of RB was severe, whereas for RB patients it was mild.
Erwenne
C M
CM
Ocular Oncology Service, A.C. Camargo Hospital/António Prudente Foundation, São Paulo, Brazil.
Pacheco
J C
JC
D000293:Adolescent; D000328:Adult; D001938:Brazil; D005134:Eye Neoplasms / Q000235:genetics*; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000235:genetics; D010375:Pedigree; D012175:Retinoblastoma / Q000235:genetics*; D012307:Risk Factors