First peak insulin release after intravenous glucose and arginine is maintained for up to 3 years after segmental pancreas transplantation.
In this study we have investigated blood glucose and serum free insulin response to glucose and to arginine orally or intravenously, 3 months and 3 years after a successful segmental, neoprene-injected, pancreas transplantation. Serum insulin responses to different secretagogues were normal 3 months after transplantation; they remained normal up to 3 years after transplantation.
Department of Internal Medicine, Istituto Scientifico San Raffaele, Milan, Italy.
A
A
Secchi
S
S
Martinenghi
R
R
Caldara
E
E
La Rocca
V
V
Di Carlo
G
G
Pozza
D001120:Arginine; D001786:Blood Glucose / Q000378:metabolism*; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology / Q000601:surgery*; D003928:Diabetic Nephropathies / Q000601:surgery; D005500:Follow-Up Studies; D005951:Glucose Tolerance Test; D006801:Humans; D007328:Insulin / Q000097:blood / Q000378:metabolism*; D000078790:Insulin Secretion; D016030:Kidney Transplantation / Q000502:physiology; D016035:Pancreas Transplantation / Q000502:physiology*
D001786:Blood Glucose; D007328:Insulin; D001120:Arginine