DNA analysis of a patient with two different marker chromosomes using Y-specific DNA probes.
A female patient with unilateral gonadal dysgenesis was a mosaic for three cell lines, 45,X/46,X, + marI/46,X, + marII, including two different marker chromosomes. DNA analysis using 17 Y-specific DNA probes revealed that each marker consists of different segments of the Y chromosome.
Tamura
T
T
Department of Congenital Abnormalities Research, National Children's Medical Research Center, Tokyo, Japan.
Kuroki
Y
Y
Nagafuchi
S
S
Suwa
S
S
Nakahori
Y
Y
Terashima
K
K
Furusho
T
T
Nakagome
Y
Y
D015139:Blotting, Southern; D002460:Cell Line; D002869:Chromosome Aberrations; D002874:Chromosome Mapping; D015342:DNA Probes / Q000235:genetics; D005260:Female; D005819:Genetic Markers / Q000235:genetics; D006059:Gonadal Dysgenesis / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D009030:Mosaicism / Q000235:genetics*; D014998:Y Chromosome
D015342:DNA Probes; D005819:Genetic Markers