Concentration of Tc-99m MDP in ovarian carcinoma and its soft tissue metastases.
A patient with ovarian carcinoma was evaluated for skeletal metastasis with a routine whole body bone scan. Although no bone metastases were visualized, there was dramatic accumulation of tracer in the soft tissues of the abdomen. CT revealed calcifying soft tissue metastases on the liver surface, the bowel serosa, and in the pelvis corresponding to the abnormal areas of Tc-99m MDP uptake. Tumor necrosis and ongoing calcification within the metastatic sites are possible explanations for this unusual soft tissue concentration of the bone-seeking radiopharmaceutical. In patients with metastatic ovarian carcinoma, careful review of extraosseous regions on bone scan images may provide valuable diagnostic information.
Department of Radiology, Medical College of Wisconsin, Milwaukee.
R A
RA
Beres
N
N
Patel
A Z
AZ
Krasnow
A T
AT
Isitman
R S
RS
Hellman
P
P
Veluvolu
R S
RS
Patillo
B D
BD
Collier
D000008:Abdominal Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D002291:Carcinoma, Papillary / Q000000981:diagnostic imaging / Q000556:secondary*; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000473:pathology*; D011877:Radionuclide Imaging; D012983:Soft Tissue Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D013669:Technetium Tc 99m Medronate
D013669:Technetium Tc 99m Medronate