[Selenium concentrations in serum, hair and tumor tissue from patients with ovarian tumors].
Selenium (Se) concentration was determined in 150 samples of serum, 135 samples of hair and 96 samples of ovarian tissue from patients with malignant or benign ovarian tumors and normal subjects. The serum Se level in patients with malignant ovarian tumors was significantly lower than that in patients with benign ovarian tumors and normal subjects. No difference of Se concentrations of hair among different groups was observed. Se level in malignant ovarian tumor tissue was significantly higher than that in benign ovarian tumor tissue and normal ovarian tissue. The low serum Se level in patients with malignant ovarian tumors was probably the result of protective migration of Se from blood to the cancer tissue.
First Affiliated Hospital, Tianjin Medical College.
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Xue
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Zhang
D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000737:chemistry; D003884:Dermoid Cyst / Q000737:chemistry; D005260:Female; D006197:Hair / Q000737:chemistry; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000737:chemistry*; D012643:Selenium / Q000032:analysis* / Q000097:blood
D012643:Selenium