Screening for unruptured familial intracranial aneurysms: subarachnoid hemorrhage 2 years after angiography negative for aneurysms.
The screening of asymptomatic individuals in families with intracranial aneurysms has been advocated to detect unruptured aneurysms before a major hemorrhage occurs. We report a 39-year-old male member of a large Dutch family, with a documented history of intracranial aneurysms, who suffered a subarachnoid hemorrhage 2 years after cerebral digital subtraction angiography using intravenously administered contrast medium showed no abnormalities. Conventional arteriography demonstrated three intracranial aneurysms measuring 3 x 3 mm. Potential alternative screening procedures are discussed.
Department of Neurology, University of Amsterdam, The Netherlands.
W I
WI
Schievink
M
M
Limburg
J J
JJ
Dreissen
F L
FL
Peeters
H W
HW
ter Berg
D000328:Adult; D015901:Angiography, Digital Subtraction; D002533:Cerebral Angiography; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications / Q000000981:diagnostic imaging* / Q000235:genetics; D008297:Male; D008403:Mass Screening; D012422:Rupture, Spontaneous; D013345:Subarachnoid Hemorrhage / Q000209:etiology*