Porous phase model of the lung interstitial fluid motion.
A mathematical model of nonsteady-state fluid movement in the lung interstitium during hydrodynamic loading is evaluated. The model is based on experimental results obtained in isolated perfused canine lungs. The interstitium is treated as a porous phase with an elastic framework, able to relax; all resistance to flux is in the interstitial tissue and not in the endothelium. A numerical iteration procedure was applied for the calculation of fluid transfer coefficients. The model describes space distribution of driving pressures in the interstitium.
Serikov
V B
VB
Laboratory of Medical Research and Technology, Association Alpha, Leningrad, USSR.
D000818:Animals; D001783:Blood Flow Velocity; D002199:Capillary Permeability; D002200:Capillary Resistance; D004285:Dogs; D005260:Female; D008168:Lung / Q000098:blood supply / Q000502:physiology*; D008196:Lymph / Q000502:physiology*; D008297:Male; D008433:Mathematics; D008954:Models, Biological; D009997:Osmotic Pressure; D010477:Perfusion / Q000295:instrumentation / Q000379:methods