Polymorphism of complement component I in Mongoloid populations: a new genetic variant IF A2.
The genetic polymorphism of the complement component I (IF) was investigated in 282 Chinese, 239 Koreans and 198 Japanese. The 3 common IF phenotypes (A, AB and B) and a new rare IF phenotype (BA2) were observed. The obtained allele frequencies are as follows: IF*A = 0.0993 and IF*B = 0.9007 in Chinese; IF*A = 0.0921 and IF*B = 0.9079 in Koreans; IF*A = 0.0985, IF*B = 0.8990 and IF*A2 = 0.0025 in Japanese. These 3 Mongoloid populations showed a much higher degree of IF polymorphism than Caucasian populations.
Department of Forensic Serology, Faculty of Forensic Medicine, China Medical University, Shenyang.
M
M
Ding
K
K
Umetsu
I
I
Yuasa
S
S
Nakamura
W Y
WY
Choi
T
T
Suzuki
D000483:Alleles; D044466:Asian People / Q000235:genetics*; D002681:China; D005340:Fibrinogen / Q000235:genetics*; D014644:Genetic Variation / Q000235:genetics*; D006801:Humans; D007564:Japan; D007723:Korea; D010641:Phenotype; D011110:Polymorphism, Genetic / Q000235:genetics*
D005340:Fibrinogen