[Auricular chondritis, malignant glomerulonephritis and pulmonary hemorrhage].
Relapsing polychondritis is a rare connective tissue disorder characterized by inflammation of cartilagenous structures such as ears, nose, joints, trachea and larynx. Renal disease is unusual. A 41 years old man presented with auricular chondritis, subacute renal failure and lung hemorrhage. A renal biopsy disclosed a diffuse proliferative glomerulonephritis with extensive crescents. Immunofluorescent studies suggested a GNRP type III so called "non immunologic disease". He was treated by prednisone and plasmapheresis with rapid disappearance of pulmonary hemorrhages and good renal functional improvement.
Clinique Néphrologique, Hôpital Calmette, Lille.
M
M
Dracon
C
C
Noël
P
P
Ramon
B
B
Wallaert
A B
AB
Tonnel
B
B
Gosselin
G
G
Lelièvre
A
A
Tacquet
D000328:Adult; D005921:Glomerulonephritis / Q000150:complications* / Q000473:pathology; D006470:Hemorrhage / Q000150:complications*; D006801:Humans; D008171:Lung Diseases / Q000150:complications*; D008297:Male; D010956:Plasmapheresis; D011081:Polychondritis, Relapsing / Q000150:complications* / Q000628:therapy; D011241:Prednisone / Q000627:therapeutic use
D011241:Prednisone
Chondrite auriculaire, glomérulonéphrite maligne et hémorragies pulmonaires.