[Multiple myeloma with hemolytic anemia and thrombocytopenia].
We report a 59 year old female patient who was diagnosed as having IgG kappa myeloma with hemolytic anemia and thrombocytopenia simultaneously. Although M-protein was suspected to contribute to the hemolysis, the IgG purified from the patient's serum did not bind to red blood cells. Therefore, massive non-specific binding of M-protein to blood cells might contribute to high levels of red blood cell-associated IgG and platelet-associated IgG in the patient.
Department of Medicine, Jichi Medical School.
K
K
Muroi
S
S
Imagawa
T
T
Suda
E
E
Kajii
Y
Y
Otuka
I
I
Sakurabayashi
Y
Y
Amemiya
S
S
Sakamoto
Y
Y
Miura
D000743:Anemia, Hemolytic / Q000150:complications*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000276:immunology; D013921:Thrombocytopenia / Q000150:complications*
D007074:Immunoglobulin G