Tone, autoregulatory properties, and wall thickness-to-radius ratio in skeletal muscle arterioles.
Internal diameter, wall thickness, wall thickness-to-radius ratio (W/r), and blood flow velocity in arterioles of different branching orders were measured in the rat cremaster muscle. The heterogeneity of W/r increased in more distal orders. During papaverine treatment, there was a direct correlation between vasodilation and W/r. When pressure was decreased by 20%, 42% of arterioles showed autoregulation; the remaining arterioles constricted in proportion to initial W/r. Similarly, the dilatation of arterioles with autoregulatory properties increased with initial W/r. It is concluded that W/r is an important parameter quantitatively related to tone, mechanical characteristics, and autoregulatory properties of arterioles.
Department of Human and Animal Physiology, Biology Faculty, Moscow State University, Union of Soviet Socialist Republics.
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EY
Kostromina
I M
IM
Rodionov
V S
VS
Shinkarenko
D000818:Animals; D001160:Arterioles / Q000033:anatomy & histology / Q000502:physiology*; D001783:Blood Flow Velocity; D001794:Blood Pressure; D001808:Blood Vessels / Q000502:physiology; D006706:Homeostasis; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000502:physiology; D009132:Muscles / Q000098:blood supply*; D051381:Rats; D011919:Rats, Inbred Strains; D014666:Vasomotor System / Q000502:physiology*