SEPIVAC: a community-based study of stroke incidence in Umbria, Italy.
The SEPIVAC study is a community-based epidemiological survey of incidence and outcome of acute cerebrovascular disease in the Sixth Local Health Unit, Umbria, Italy (population 49,218). The study was carried out from 1 September 1986 to 31 August 1989. There were 375 patients who were registered with a first ever stroke, with a crude rate of 2.54 (95% confidence limits 2.29-2.81) per 1000 per year; the rate adjusted to the European population is 1.55 (CL 1.36-1.77). The age adjusted relative risk for males is 1.35 (CL 1.10-1.66). Up to 15% of the patients were not admitted to hospital during the acute phase of their disease. At least 286 (76.3%, CL 72-80.6) of the cases were due to cerebral ischaemia; in 56 of these (19.6%, CL 15-24.2) a clinical diagnosis of lacunar ischaemia was made. The 30 day case fatality rate was 20.3% (CL 16.2-24.3); between one and six months 7.5% (CL 5-10.6) of patients died.
Perugia University Hospital, Italy.
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S
Ricci
M G
MG
Celani
F
F
La Rosa
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R
Vitali
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E
Duca
R
R
Ferraguzzi
M
M
Paolotti
D
D
Seppoloni
N
N
Caputo
C
C
Chiurulla
D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000000981:diagnostic imaging / Q000401:mortality; D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging / Q000401:mortality; D002544:Cerebral Infarction / Q000000981:diagnostic imaging / Q000401:mortality; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging / Q000401:mortality*; D003431:Cross-Cultural Comparison; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed