Unilateral acute idiopathic maculopathy.
This is a report of nine patients who experienced sudden, severe, unilateral central vision loss following a flulike illness. Each patient had an exudative detachment of the macula. All patients experienced a spontaneous resolution of the acute macular manifestations with near-complete recovery of vision. A characteristic "bull's-eye" appearance in the macula persisted. The acute manifestations of the disorder did not recur in any of the patients during the period of follow-up. The constellation of findings was suggestive of an inflammatory disease of the retinal pigment epithelium, but a specific causative agent could not be identified. The acute clinical and angiographic features, the natural course, and the residual pigment epithelial derangement were not consistent with any previously described disorder.
LuEsther T. Mertz Retinal Research Laboratory, Manhattan Eye, Ear and Throat Hospital, New York, NY 10021.
L A
LA
Yannuzzi
L M
LM
Jampol
M F
MF
Rabb
J A
JA
Sorenson
C
C
Beyrer
L M
LM
Wilcox
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001766:Blindness / Q000209:etiology; D003937:Diagnosis, Differential; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology; D012141:Respiratory Tract Infections / Q000150:complications; D012163:Retinal Detachment / Q000473:pathology; D012164:Retinal Diseases / Q000175:diagnosis / Q000473:pathology*; D014792:Visual Acuity