Neovascular glaucoma, endophthalmitis and evisceration.
A retrospective study of 35 patients undergoing evisceration at Moorfields Eye Hospital, London between 1982 and 1987, revealed that 60% were known to be suffering from neovascular glaucoma, the majority as a result of a central retinal vein occlusion. 76% of these rubeotic eyes subsequently developed an endophthalmitis and required evisceration. 81% of this rubeotic, infected group were being treated with topical steroids prior to developing a suppurative keratitis and ensuing endophthalmitis. Every patient (9) with neovascular glaucoma that was debilitated (due to a variety of underlying medical conditions--4 were diabetic) developed an endophthalmitis and 78% of these were also using topical steroids. This study reveals that there may be a specific group of patients with absolute neovascular glaucoma, i.e. being debilitated and using topical steroids, who might appear to be susceptible to developing severe intraocular infection.
Department of Ophthalmology, University of Birmingham, U.K.
P I
PI
Murray
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D009877:Endophthalmitis / Q000209:etiology / Q000601:surgery*; D015353:Eye Enucleation; D015818:Eye Infections, Bacterial / Q000209:etiology / Q000601:surgery*; D005260:Female; D015355:Glaucoma, Neovascular / Q000209:etiology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000150:complications / Q000188:drug therapy; D012189:Retrospective Studies; D013256:Steroids / Q000627:therapeutic use
D013256:Steroids