Cytogenetic studies in patients with multiple myeloma.
Fourteen patients diagnosed as having multiple myeloma were studied cytogenetically. In eight patients a sufficient number of metaphases was obtained and four of them showed abnormal karyotypes of bone marrow cells. Hypodiploidy was a consistent finding, as was the involvement of chromosome 9.
Institute of Pediatrics, Medical Academy, Lublin, Poland.
J R
JR
Kowalczyk
A
A
Dmoszyńska
M
M
Chobotow
B
B
Sokolowska
D001853:Bone Marrow / Q000648:ultrastructure; D002869:Chromosome Aberrations; D004171:Diploidy; D005260:Female; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000032:analysis; D007146:Immunoglobulin lambda-Chains / Q000032:analysis; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000235:genetics* / Q000276:immunology
D007145:Immunoglobulin kappa-Chains; D007146:Immunoglobulin lambda-Chains