[A study on factors influencing the stability of total nutrient admixture].
To study the stability of total nutrient admixture, glucose, amino acid, fat emulsion, electrolyte, and other nutrients in different combinations and concentrations were admixed and infused into 16 3-liter polyvinyl chloride bags, which at last were stored at 4 degrees C, 22-25 degrees C, 32 degrees C, respectively. Samples were inspected at 0, 12, 24 and 48 hours. The results showed that the admixture was stable when total concentration of mono cation was lower than 150 mmol/L, Mg2+ less than 3.4 mmol/L, and Ca2+ less than 1.7 mmol/L, stored at 4 degrees C for 48 hours, or at 22-25 degrees C for 24 hours. We conclude that PVC 3L container is safe for storage of TNA at least within 24 hours.
Zhang
L H
LH
General Hospital of Nanjing Unit of People's Liberation Army.
D000596:Amino Acids / Q000008:administration & dosage; D004355:Drug Stability; D004573:Electrolytes / Q000008:administration & dosage; D005217:Fat Emulsions, Intravenous / Q000008:administration & dosage; D005947:Glucose / Q000008:administration & dosage; D010289:Parenteral Nutrition, Total; D011145:Polyvinyls; D012996:Solutions; D013696:Temperature; D013997:Time Factors
D000596:Amino Acids; D004573:Electrolytes; D005217:Fat Emulsions, Intravenous; D011145:Polyvinyls; D012996:Solutions; D005947:Glucose