Remarkable improvement of neuropsychiatric symptoms in HIV-infected patients after AZT therapy.
Treatment of neuropsychiatric symptoms with AZT (Azidothymidine) seems to be effective in many AIDS patients. In earlier studies, 204 of 525 patients treated with AZT showed neuropsychiatric improvement. In this presentation, two patients with affective disorder and dementia are described. Both patients showed remarkable improvement of their severe psychiatric symptoms after AZT. The authors recommend treatment of AIDS-associated dementia and psychoorganic symptoms with AZT.
Psychiatrische Klinik und Poliklinik, Universität München.
M
M
Hollweg
R R
RR
Riedel
F D
FD
Goebel
U
U
Schick
D
D
Naber
D015526:AIDS Dementia Complex / Q000188:drug therapy* / Q000523:psychology; D000328:Adult; D001143:Arousal / Q000187:drug effects; D001288:Attention / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D014057:Tomography, X-Ray Computed; D015215:Zidovudine / Q000627:therapeutic use*
D015215:Zidovudine