[Psychomotor development of children at risk with special reference to prenatal, intrapartum and postnatal hypoxia].
In a prospective study the psychomotor development of an unselected collective of high risk newborn infants up to the end of the second year of life was examined. The proof of hypoxia was performed with the erythrocytic density test (EDT). The value of EDT showed a decline with the age of life, and it was independent of gestational age or of birthweight only at the first point of determination (cord blood, first or second day of life). Significant connections between the level of light red blood cells and the children's development could not be demonstrated, although the probability to develop psychomotor disabilities increased in the newborn with a positive value of EDT. The diagnostic value of EDT showed the best results for intrapartum and postnatal hypoxia. The highest specificity was calculated with 38.0%, if the sensitivity is 80.0%. In conclusion of these results it's not to be recommended to use the EDT alone for the prediction of individual prognosis of children.
Abel
H T
HT
Frühgeborenenzentrum, Medizinischen Akademie Magdeburg.
Korb
C
C
Fritzsche
K
K
Köditz
H
H
D002657:Child Development; D002675:Child, Preschool; D004906:Erythrocyte Count; D005312:Fetal Blood; D005311:Fetal Hypoxia / Q000523:psychology*; D006801:Humans; D000860:Hypoxia / Q000097:blood / Q000523:psychology*; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D011379:Prognosis; D011446:Prospective Studies; D012307:Risk Factors; D012680:Sensitivity and Specificity
Psychomotorische Entwicklung von Risikokindern unter Berücksichtigung prä-, intra- und postnataler Hypoxien.