Mapping of the MYC gene to band 8q24.12----q24.13 by R-banding and distal to fra(8)(q24.11), FRA8E, by fluorescence in situ hybridization.
The MYC gene was mapped to R-banded human prometaphase chromosomes and to chromosomes expressing fra(8)(q24.11) by fluorescence in situ hybridization. By high-resolution banding analysis, the fluorescent signals were localized to R-positive band q24.12----q24.13 of the long arm of chromosome 8. Furthermore, the signals were localized near the middle part, q24.12----q24.13, of the distal portion of fra(8)(q24.11) expression. Thus, the precise localization of MYC was to the subband 8q24.12----q24.13.
Division of Genetics, National Institute of Radiological Sciences, Chiba, Japan.
E
E
Takahashi
T
T
Hori
P
P
O'Connell
M
M
Leppert
R
R
White
D002871:Chromosome Banding; D002874:Chromosome Mapping; D002898:Chromosomes, Human, Pair 8; D015342:DNA Probes; D016259:Genes, myc; D005819:Genetic Markers; D006801:Humans; D007621:Karyotyping; D008214:Lymphocytes / Q000166:cytology; D008856:Microscopy, Fluorescence; D009693:Nucleic Acid Hybridization
D015342:DNA Probes; D005819:Genetic Markers