[Elevated plasma interleukin-6 in patient with idiopathic thrombocytopenic purpura].
Plasma Interleukin-6 (IL-6) level was measured in patients with idiopathic thrombocytopenic purpura (ITP), systemic lupus erythematosus (SLE), rheumatoid arthritis and aplastic anemia. Increase in the plasma level of IL-6 was observed in patients with ITP and SLE. The plasma IL-6 level decreased with progression of the treatment for ITP, and it showed weak negative correlations with the platelet count at the onset of ITP. The increases in the plasma IL-6 level suggest the involvement of activation of the immune system in the pathogenesis of ITP.
2nd Department of Internal Medicine, Mie University School of Medicine.
H
H
Wada
K
K
Minamikawa
M
M
Ohiwa
T
T
Kaneko
Y
Y
Mori
S
S
Tamaki
M
M
Takagi
S
S
Kageyama
N
N
Katayama
N
N
Minami
D000293:Adolescent; D000328:Adult; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D008180:Lupus Erythematosus, Systemic / Q000276:immunology; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000276:immunology*; D012015:Reference Standards
D015850:Interleukin-6