Cardiac tumors: assessment with Gd-DTPA enhanced MR imaging.
Previous studies have shown the value of MR imaging for the identification of cardiac masses. The distinction of intramural tumors from normal myocardium may be equivocal because of the similarity of signal intensity between tumor and normal myocardium on ECG-gated SE images. The purpose of this study was to assess the role of Gd-DTPA for improving the contrast between cardiac tumors and myocardium. Four patients with established or suspected cardiac tumors were imaged with a 1.5 T imager. The T1-weighted images (TR = RR interval, TE = 20-30 ms) were obtained before and immediately after the intravenous injection of Gd-DTPA, at a dosage of 0.1 mmol/kg. Tumors were identified in three patients. All tumors were isointense to the myocardium in precontrast images but demonstrated differential enhancement relative to myocardium after the administration of Gd-DTPA. Two tumors were hyperintense relative to myocardium, and the third was mostly hypointense, surrounded by a hyperintense rim. In the remaining case, no tumor was found and the myocardium was homogeneously enhanced on postgadolinium images. Gadolinium DTPA can produce differential enhancement of tumor from normal myocardium and therefore demonstrate intramural masses.
Department of Radiology, University of California, San Francisco 94143.
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Funari
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Fujita
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Peck
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Higgins
D000368:Aged; D002276:Carcinoid Tumor / Q000175:diagnosis; D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis; D002648:Child; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D005350:Fibroma / Q000175:diagnosis; D019786:Gadolinium DTPA; D006338:Heart Neoplasms / Q000175:diagnosis* / Q000556:secondary; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009232:Myxoma / Q000175:diagnosis; D009942:Organometallic Compounds; D004369:Pentetic Acid
D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA