[The stimulating effect of prolactin on the neurite growth of sensory neurons in an organotypic culture].
Prolactine was found to promote neurite extension in chick embryo dorsal root ganglia in vitro. This hormone was active at the concentration 10-50 ng/ml provided extensive neurite outgrowth in the bioassay, compared to the control. The liquor from patients with prolactinoma was also found to promote neurite extension. This fact may be used for prolactinoma diagnostics.
Chalisova
N I
NI
Mel'kishev
V F
VF
Akoev
G N
GN
Liudyno
M I
MI
Kurenkova
T Iu
TIu
D000818:Animals; D002642:Chick Embryo; D046508:Culture Techniques; D004305:Dose-Response Relationship, Drug; D005727:Ganglia, Spinal / Q000187:drug effects / Q000648:ultrastructure; D013006:Growth Hormone / Q000494:pharmacology; D006801:Humans; D016501:Neurites / Q000187:drug effects* / Q000502:physiology; D009475:Neurons, Afferent / Q000187:drug effects* / Q000502:physiology; D010911:Pituitary Neoplasms / Q000134:cerebrospinal fluid; D011388:Prolactin / Q000494:pharmacology*; D015175:Prolactinoma / Q000134:cerebrospinal fluid
D011388:Prolactin; D013006:Growth Hormone
Stimuliruiushchee vliianie prolaktina na rost neĭritov chuvstvitel'nykh neĭronov v organotipicheskoĭ kul'ture.