Hürthle cell carcinoma of the thyroglossal duct.
A thyroglossal duct cyst is an embryologic remnant that often manifests as a swelling in the midline of the neck. The development of a carcinoma in a cyst is rare but well recognized. The majority of those reported are papillary carcinoma; there have been 4 cases of mixed follicular-papillary (which biologically and clinically behaves as a papillary carcinoma) and only 1 follicular. A computer search of the literature revealed no previous report of a Hürthle cell carcinoma arising in a thyroglossal duct. A case of Hürthle cell carcinoma arising in a thyroglossal duct is presented, and the pathology, clinical manifestations, and management are reviewed.
Department of Otolaryngology, Mount Sinai Hospital, University of Toronto, Ontario, Canada.
M
M
Adler
J L
JL
Freeman
D002277:Carcinoma / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D013955:Thyroglossal Cyst / Q000150:complications* / Q000473:pathology / Q000601:surgery; D013964:Thyroid Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D013965:Thyroidectomy