Oxygen radicals and lung injury.
This article describes the formation of oxygen radicals and their biological effects, especially in relation to lung injury. Various recent experimental data are reviewed. The relationships between hydrostatic effects and permeability effects in producing injury and edema are stressed. Means of prevention and problems related to extrapolation to clinical situations are focused.
Department of Surgery, Ostra Sjukhuset, University of Göteborg, Sweden.
B
B
Risberg
L
L
Smith
P
P
Ortenwall
D000818:Animals; D005609:Free Radicals; D066298:In Vitro Techniques; D008171:Lung Diseases / Q000209:etiology* / Q000517:prevention & control; D010100:Oxygen / Q000009:adverse effects*; D014969:Xanthine Oxidase / Q000378:metabolism
D005609:Free Radicals; D014969:Xanthine Oxidase; D010100:Oxygen