[A case of pustulotic arthro-osteitis with secondary amyloidosis].
A 63-year-old man with a history of Pustulosis Palmaris et Plantaris since 1960 was suffered from lumbago and anterior chest pain in 1973. Chest X-ray film showed inter-sterno-costo-clavicular ossification. Spondylodiscitis, Syndesmophyte of lumbal spine, Sacro-iliitis were seen by abdominal X-ray film. He was admitted to near hospital with generalized edema and urinary protein (10-20 g/day) in April 1986. Laboratory studies showed hypoproteinemia, positive C-reactive protein, high serum amyloid A protein(240 ng/100 microliters) and negative HL-A B27. He was diagnosed Pustulotic arthro-osteitis and Secondary Amyloidosis by renal biopsy and rectal biopsy in 1987. He was treated with high-dose oral prednisolone(60 mg/day)and dimethyl sulfoxide. After treatment, Edema and Nephrose improved. Increasement of renal function was not observed.
Second Department of Internal Medicine, Fukushima Medical College.
T
T
Kanno
Y
Y
Funabashi
T
T
Nishimaki
R
R
Kasukawa
K
K
Sagawa
D000686:Amyloidosis / Q000188:drug therapy / Q000209:etiology*; D015535:Arthritis, Psoriatic / Q000150:complications* / Q000188:drug therapy; D004121:Dimethyl Sulfoxide / Q000008:administration & dosage; D006801:Humans; D007674:Kidney Diseases / Q000188:drug therapy / Q000209:etiology*; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage; D011859:Radiography; D000685:Serum Amyloid A Protein / Q000032:analysis
D000685:Serum Amyloid A Protein; D011239:Prednisolone; D004121:Dimethyl Sulfoxide