Topical minoxidil in the treatment of androgenetic alopecia in women.
Twenty-eight women with mild to moderate androgenetic alopecia were randomly assigned to apply either 2 percent topical minoxidil or placebo (vehicle) to their involved scalp areas twice daily. At the end of thirty-two weeks, there was a statistically significant increase of nonvellus target area hairs in the minoxidil-treated versus the vehicle-treated group (p = 0.006). Investigator assessment of moderate regrowth showed better results in subjects who used 2 percent topical minoxidil solution than those who used vehicle (p = 0.007), although subjects discerned no difference between treatment groups. Two percent topical minoxidil appears to be effective in the treatment of female androgenetic alopecia.
Olsen
E A
EA
Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710.
D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000506:Alopecia Areata / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008875:Middle Aged; D008914:Minoxidil / Q000008:administration & dosage*
D008914:Minoxidil