Carpentier-Edwards porcine bioprostheses. Comparison of standard and supra-annular prostheses at 7 years.
The performance of the Carpentier-Edwards supra-annular (CE-SAV) porcine bioprosthesis is compared with the Carpentier-Edwards standard (CE-S) porcine bioprosthesis at 7 years. The standard prosthesis was implanted in 1,195 patients between 1975 and 1987, while the supra-annular prosthesis was implanted in 1,956 patients between 1982 and 1989. The total follow-up for the standard prosthesis was 8,850 patient-years with a mean follow-up of 7.4 years, while for the supra-annular prosthesis it was 7,317 years with a mean of 3.7 years. The follow-up for the standard prosthesis was 96.7% and for the supra-annular prosthesis was 97.6%. The freedom from structural valve deterioration (SVD) for aortic replacements is 96.1 +/- 0.9% for CE-S and 97.6 +/- 1.4% for CE-SAV at 7 years (p = NS). The freedom for mitral replacements from SVD is 89.1 +/- 1.7% and 88.6 +/- 2.8%, respectively, for CE-S and CE-SAV (p = NS). The freedom for multiple replacements at 7 years was 80.0 +/- 4.5% for CE-S and 97.8 +/- 1.5% for CE-SAV (p less than or equal to 0.05). The freedom from SVD for the age group equal to or less than 35 years is 79.0 +/- 4.7% for CE-S and 85.0 +/- 9.4% for CE-SAV (p = NS). The freedom for the age group 36-50 years is 85.2 +/- 2.8% and 90.4 +/- 4.5%, respectively, at seven years for the CE-S and CE-SAV prostheses (p = NS).(ABSTRACT TRUNCATED AT 250 WORDS)
Department of Surgery, Vancouver General Hospital, Canada.
W R
WR
Jamieson
G F
GF
Tyers
R T
RT
Miyagishima
E
E
Germann
M T
MT
Janusz
H
H
Ling
D000206:Actuarial Analysis; D000328:Adult; D000368:Aged; D001705:Bioprosthesis; D005260:Female; D005500:Follow-Up Studies; D006349:Heart Valve Diseases / Q000453:epidemiology / Q000601:surgery; D006350:Heart Valve Prosthesis; D006351:Heart Valves; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D011474:Prosthesis Design; D011475:Prosthesis Failure; D013997:Time Factors