Vidalols A and B, new anti-inflammatory bromophenols from the Caribbean marine red alga Vidalia obtusaloba.
Chemical studies of the Caribbean red alga Vidalia obtusaloba have resulted in the isolation of two new bromophenolic metabolites, vidalols A and B (1, 2). The new compounds were discovered as part of an organized effort to isolate new naturally-occurring anti-inflammatory agents with a focus upon those which may function through the inhibition of phospholipase A2.
Wiemer
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Scripps Institution of Oceanography, University of California, San Diego, La Jolla 92093-0236.
Idler
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Fenical
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D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001969:Bromobenzenes; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D051379:Mice; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D010696:Phloroglucinol / Q000031:analogs & derivatives; D010741:Phospholipases A / Q000037:antagonists & inhibitors; D054467:Phospholipases A2; D000461:Rhodophyta / Q000737:chemistry*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D001969:Bromobenzenes; D010636:Phenols; C071024:vidalol A; C071025:vidalol B; D010696:Phloroglucinol; D010741:Phospholipases A; D054467:Phospholipases A2