Necrotizing sialometaplasia. A clinicopathologic study of sixty-nine cases and review of the literature.
The clinicopathologic findings in 69 cases of necrotizing sialometaplasia (NS) were analyzed and compared with 115 reported cases of NS in the English-language literature. Data comparing age, sex, race, location, clinical presentation, and possible predisposing factors are summarized. Analysis of the data indicates that NS can occur in a variety of clinical settings and may exhibit a spectrum of histologic features. Recognition of NS, regardless of its clinical or microscopic presentation, is essential to avoid inappropriate or unnecessary treatment for this benign reactive process.
Brannon
R B
RB
Department of Oral Pathology, Wilford Hall USAF Medical Center, Lackland Air Force Base, Tex.
Fowler
C B
CB
Hartman
K S
KS
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D012469:Salivary Glands / Q000098:blood supply; D012704:Serous Membrane / Q000098:blood supply; D012797:Sialometaplasia, Necrotizing / Q000473:pathology*