Immunogenetics of the human major histocompatibility complex.
The biologic significance of the human major histocompatibility complex (MHC), also referred to as HLA, is well known through its influence on transplant immunity and its association with many diseases. This article attempts to summarize recent progress in the field of HLA polymorphisms. Topics discussed include the genetic basis of HLA, methods to determine HLA polymorphisms, and definitions of HLA Class I and II polymorphisms.
Duquesnoy
R J
RJ
University of Pittsburgh School of Medicine, Pennsylvania.
D005805:Genes, MHC Class I; D005802:Genes, MHC Class II; D006680:HLA Antigens / Q000737:chemistry / Q000235:genetics; D006650:Histocompatibility Testing; D006801:Humans; D007125:Immunogenetics; D008285:Major Histocompatibility Complex; D008958:Models, Molecular; D011110:Polymorphism, Genetic; D014019:Tissue Donors; D014181:Transplantation Immunology
D006680:HLA Antigens