[Glutamate decarboxylase and GABA transaminase activity in the mitochondrial fraction of the dog brain limbic system during postnatal development].
Overall glutamate decarboxylase (GDCase) activity in the initial mitochondrial fraction of the limbic structure is found to be regionally different it increases from the moment of birth up to 1 year, the midbrain reticular formation (RF), where the enzyme activity in the mitochondrial decreases in pups aged 3 month and reincreases in 1 year old dogs being the exception. Overall GABA-transaminase (GABA-T-ase) activity reaches the "adult" level and is the highest: in the hypothalamic and hippocampal mitochondria on the 1st postnatal day; in the limbic cortex (l1 and l2 fields), amygdala and midbrain RF--on the 12-16th postnatal days. During the period from 12-16 postnatal days up to the age of 1 year GABA-T-ase activity in the dog limbic system decreases reliably.
Faradzhev
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D000612:4-Aminobutyrate Transaminase / Q000378:metabolism*; D000375:Aging / Q000378:metabolism; D000818:Animals; D004285:Dogs; D005968:Glutamate Decarboxylase / Q000378:metabolism*; D008032:Limbic System / Q000201:enzymology* / Q000254:growth & development; D008928:Mitochondria / Q000201:enzymology
D000612:4-Aminobutyrate Transaminase; D005968:Glutamate Decarboxylase
Glutamatdekarboksilaznaia i GAMK-transaminaznaia aktivnost' v mitokhondrial'noĭ fraktsii struktur limbicheskoi sistemy mozga sobak v postnatal'nom ontogeneze.