Bladder dysfunction due to human T-lymphotrophic virus type I associated myelopathy.
Bladder dysfunction is a major complication of human T-lymphotrophic virus type I associated myelopathy (HAM). Four patients (3 females and 1 male, aged between 23 and 44 years), who had suffered from HAM for an average of 6 years complained variously of difficulty in micturition, frequency, bed wetting and/or urge incontinence. They were investigated urodynamically. A significant amount of urine was retained in the bladder of 3 patients. During the storage phase, bladder sensation was well preserved in all 4 patients but severe uninhibited detrusor contractions were observed in 3. At micturition, detrusor contractility was present in 3 and completely lost in 1. Of the 4 patients with HAM, 3 suffered from detrusor hyper-reflexia and 1 from detrusor areflexia.
Department of Urology, Nagoya University School of Medicine, Japan.
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M
Saito
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A
Kondo
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K
Kato
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M
Gotoh
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D009119:Muscle Contraction / Q000502:physiology; D015493:Paraparesis, Tropical Spastic / Q000150:complications* / Q000503:physiopathology; D001743:Urinary Bladder / Q000503:physiopathology; D014555:Urination Disorders / Q000209:etiology* / Q000503:physiopathology; D014563:Urodynamics