Disorders of oesophageal motility in children with psychomotor retardation and gastro-oesophageal reflux.
A group of 25 children affected by different degrees of psychomotor retardation (severe (n = 13); mild-moderate (n = 12)) and symptoms suggesting gastro-oesophageal reflux (GOR) underwent oesophageal manometry and oesophageal pH monitoring. Of these patients, 21 (84%) were affected by GOR. In all children with severe brain damage and GOR (12/13), oesophageal manometry showed marked motility abnormalities that persisted after cure of GOR. In patients with minor retardation and GOR (9/12), oesophageal manometry showed normal motility or a less severe degree of oesophageal motor dysfunction which improved after curing the GOR. These results suggest that oesophageal motor dysfunction is a frequent occurrence in children affected by severe psychomotor retardation and GOR.
Staiano
A
A
Department of Paediatrics, Second School of Medicine, University of Naples, Italy.
Cucchiara
S
S
Del Giudice
E
E
Andreotti
M R
MR
Minella
R
R
D001925:Brain Damage, Chronic / Q000150:complications*; D002675:Child, Preschool; D015154:Esophageal Motility Disorders / Q000150:complications* / Q000503:physiopathology; D005764:Gastroesophageal Reflux / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007223:Infant; D008607:Intellectual Disability / Q000150:complications*; D008365:Manometry