The antimicrobial activity of the essential oil from Achillea fragrantissima.
Essential oil from Achillea fragrantissima exerted a bactericidic effect on several gram positive and gram negative bacterial strains, as well as on Candida albicans. The oil was fractionated on sillica gel columns by a gradient of ether in petrol ether (30 degrees C-40 degrees C). Two fractions which contained less polar compounds were active against C. albicans only. The fractions which contained more polar compounds inhibited the growth of all the microorganisms tested. One of these compounds was identified as terpinen-4-ol. Commercial terpinen-4-ol had a similar antimicrobial activity.
Department of Bacteriology, Faculty of Medicine, Hebrew University, Jerusalem, Israel.
S
S
Barel
R
R
Segal
J
J
Yashphe
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D002855:Chromatography, Thin Layer; D008401:Gas Chromatography-Mass Spectrometry; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D007557:Israel; D008826:Microbial Sensitivity Tests; D009822:Oils, Volatile / Q000737:chemistry / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D009822:Oils, Volatile