Giant fibromyxoid tumors of the adventitial dermis. Forme fruste of trichodiscoma?
A 36-year-old paraplegic man developed multiple giant fibromyxoid tumors surrounding a meningomyelocele scar that we believe are forme fruste of trichodiscomas. Histologic examination showed a papillated, slightly hyperplastic epidermis surrounding a delicate fibrovascular proliferation set in a stroma of loose fibrillar connective tissue and stellate fibroblasts. A melanocytic nevus was incorporated into one of the lesions. We believe that these giant lesions are connective tissue nevi of the adventitial dermis that comprise a new clinical variant of trichodiscoma. The potential significance of the relationship between these abortive trichodiscomas and abnormalities of the neural crest is discussed.
Department of Dermatology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina.
C S
CS
McCalmont
W L
WL
White
J L
JL
Jorizzo
D000328:Adult; D002921:Cicatrix / Q000150:complications; D005350:Fibroma / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D008591:Meningomyelocele / Q000601:surgery; D009378:Neoplasms, Multiple Primary / Q000150:complications / Q000473:pathology*; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology*