Report of a fatal thiamylal intoxication.
A fatality due to the intravenous administration of thiamylal is reported. Quantitation of the drug was accomplished by high-performance liquid chromatography (HPLC) and confirmation was by gas chromatography/mass spectrometry (GC/MS). Postmortem tissue concentrations of thiamylal were as follow: 129 mg/L in blood, 366 mg/kg in liver, and 116 mg/kg in brain. Thiamylal was not detected in the urine, gastric contents, or bile. Analytical caveats involving the quantitation of thiamylal are also discussed.
Stockham
T L
TL
Office of Chief Medical Examiner, New York, NY 10016.
McGee
M P
MP
Stajic
M
M
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D013840:Thiamylal / Q000032:analysis / Q000493:pharmacokinetics / Q000506:poisoning*; D014018:Tissue Distribution
D013840:Thiamylal