Why yeast?
Yeast is an apparently strange "model" for the human genome, but it works because of the high degree of conservation in evolution between the primitive eukaryote and mammals. Moreover, the genic concentration in yeast--with almost no noncoding introns--packs the entire yeast genome into 16 chromosomes with only 10% of the DNA of one human chromosome.
Botstein
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Department of Genetics, Stanford University School of Medicine.
D015894:Genome, Human; D006801:Humans; D008957:Models, Genetic; D015003:Yeasts / Q000235:genetics*