Serological diagnosis with the Chlamydia Spot-IF test.
Using a set of sera for which full chlamydial micro-immunofluorescence results suggested a clear diagnosis, we have evaluated the Chlamydia Spot-IF test (bioMerieux), which allows a comparison of titres to Chlamydia trachomatis and C. psittaci antigens. A modification of the test in which the antigen slides were pre-treated with a monoclonal antibody to chlamydial lipopolysaccharide, improved its ability to differentiate infections with C. trachomatis from those with C. psittaci or C. pneumoniae.
Liverpool Public Health Laboratory, Fazakerley Hospital.
P T
PT
Mannion
H
H
Mallinson
J D
JD
Treharne
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002690:Chlamydia Infections / Q000097:blood / Q000175:diagnosis*; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D002691:Chlamydophila psittaci / Q000302:isolation & purification; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008070:Lipopolysaccharides / Q000276:immunology; D008297:Male; D008875:Middle Aged; D012698:Serologic Tests
D008070:Lipopolysaccharides