The conformation of echinomycin in DMSO solution.
The conformation of the antibiotic echinomycin in DMSO solution has been determined from two-dimensional NMR and distance geometry calculation with distance constraints. Five converged conformations were calculated with NOE distance constraints followed by restraint energy minimization.
Yu
C
C
Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan, Republic of China.
Yang
T H
TH
Young
J J
JJ
D004121:Dimethyl Sulfoxide; D004448:Echinomycin / Q000737:chemistry*; D004735:Energy Transfer; D009682:Magnetic Resonance Spectroscopy; D011487:Protein Conformation / Q000187:drug effects; D012996:Solutions; D013237:Stereoisomerism
D012996:Solutions; D004448:Echinomycin; D004121:Dimethyl Sulfoxide