Age-related changes in the human lens. Clinical assessment of age-related changes in the human lens.
We compared two methods for assessing changes in the human lens associated with age. The first is a subjective method for quantifying light absorption by the lens. It is useful for determining the functional effect of age-related increases in lens density, especially for short-wavelength light. The second method objectively and rapidly measures the increase in scattered light with increasing lens density. These two methods accurately measured age-related changes and were highly correlated with each other (r = 0.72, P less than 0.001). Both methods were evaluated in a population of normal eyes, eyes with ocular hypertension, and eyes with primary open angle glaucoma. We found ni significant differences among these groups with either method.
Department of Ophthalmology, University of California, San Diego.
P A
PA
Sample
J S
JS
Quirante
R N
RN
Weinreb
D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D002386:Cataract / Q000503:physiopathology; D005902:Glaucoma, Open-Angle / Q000503:physiopathology; D006801:Humans; D007908:Lens, Crystalline / Q000503:physiopathology*; D008875:Middle Aged; D009798:Ocular Hypertension / Q000503:physiopathology; D010775:Photic Stimulation; D011897:Random Allocation; D015203:Reproducibility of Results; D014787:Vision Tests / Q000379:methods