Persistent virus infections in studies of the immune response.
Some recent studies on immune phenomena in persistent virus infections, employing non-cytolytic viruses, are reviewed. This includes the refutation of a possible inheritance of tolerance and some aspects of drug-induced tolerance to persistent viruses, with its consequences for possible treatment of virus-induced immunopathological diseases. The biological peculiarities of viruses involved in persistent or chronic infections are discussed with respect to the balance between the immune system and the infectious agent.
Institut für Virologie, Justus-Liebig-Universität Giessen, Germany.
L
L
Stitz
D000818:Animals; D002908:Chronic Disease; D006801:Humans; D008216:Lymphocytic Choriomeningitis / Q000276:immunology; D008217:Lymphocytic choriomeningitis virus / Q000472:pathogenicity; D014777:Virus Diseases / Q000276:immunology*