[Neoplasms following kidney transplantation].
The incidence, predisposing factors, localization, evolution and outcome of neoplasms following kidney transplantation were studied in two groups of patients--120 and 146 patients for an observation period from 1 to 16 years. In patients with adequate renal function who received immunosuppressive treatment for more than one year (accordingly 78 and 88 patients) neoplasms developed in 4 and 10 patients with mean duration of immunosuppressive treatment 4.9 and 6.1 years respectively. The neoplasms were: 3 skin cancers, 2 lung cancers, 2 Kaposi sarcomas, 1 lymphosarcoma, 1 breast cancer, 1 prostate cancer, 1 renal cancer, 1 rectal cancer and 2 polyps of the colon. The case fatality rate was 3.6 per cent. The importance of precision of the immunosuppressive treatment for reducing the incidence of these complications is pointed out.
Beleva
B
B
D000367:Age Factors; D002031:Bulgaria / Q000453:epidemiology; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects / Q000706:statistics & numerical data; D016030:Kidney Transplantation / Q000706:statistics & numerical data; D009369:Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000401:mortality; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology* / Q000401:mortality; D012189:Retrospective Studies; D012737:Sex Factors; D013997:Time Factors
Novoobrazuvaniia sled bŭbrechna transplantatsiia.