Giant fibromyxoid tumors of the adventitial dermis. Forme fruste of trichodiscoma?
A 36-year-old paraplegic man developed multiple giant fibromyxoid tumors surrounding a meningomyelocele scar that we believe are forme fruste of trichodiscomas. Histologic examination showed a papillated, slightly hyperplastic epidermis surrounding a delicate fibrovascular proliferation set in a stroma of loose fibrillar connective tissue and stellate fibroblasts. A melanocytic nevus was incorporated into one of the lesions. We believe that these giant lesions are connective tissue nevi of the adventitial dermis that comprise a new clinical variant of trichodiscoma. The potential significance of the relationship between these abortive trichodiscomas and abnormalities of the neural crest is discussed.
McCalmont
C S
CS
Department of Dermatology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina.
White
W L
WL
Jorizzo
J L
JL
D000328:Adult; D002921:Cicatrix / Q000150:complications; D005350:Fibroma / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D008591:Meningomyelocele / Q000601:surgery; D009378:Neoplasms, Multiple Primary / Q000150:complications / Q000473:pathology*; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology*