[Changes in the Q-Tc interval in the acute phase of cerebral ischemic infarction].
A clinical prospective study was carried out in 100 patients with stroke (S) (56 with lacunar infarctions [LI] and 44 with nonlacunar infarctions [NLI]) and in a control group without organic cerebral disease (n = 100) to compare the abnormalities in the Q-Tc interval of the electrocardiogram. An abnormal Q-Tc interval (greater than 0.44 sec) was found in 18% of S and in 8% of the control subjects (p less than 0.05). These abnormalities in S were more common at the onset of the disease (18%) than from 3 weeks after the development of focal signs (9%). An abnormal Q-Tc interval was found in 18% of NLI (8 of 44 cases) and in 18% of NLI (10 of 56 cases). Regarding the topography of the lesions, an abnormal Q-Tc interval was found in 20% (3 of 15 cases) of the brainstem infarctions; in 19% of the infarctions of basal ganglia (9 of 47 cases) and in 13% (4 of 30 cases) of hemispheral strokes. Our results show that the abnormalities of Q-Tc interval in strokes are not uncommon. They may be reversible and in some cases they are related with the topography of the cerebral lesion.
Servicio de Neurología, Quinta de Salud La Alianza, Hospital Central, Barcelona.
A
A
Arboix
J
J
Alió
D000208:Acute Disease; D000368:Aged; D002545:Brain Ischemia / Q000503:physiopathology*; D002544:Cerebral Infarction / Q000503:physiopathology*; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies
Variación del intervalo Q-Tc en la fase aguda del infarto isquémico cerebral.