[The effect of a high-saccharose diet on the enzymatic activity of the oral mucosa in rats].
Cathepsin D, acid phosphatase, beta-galactosidase, N-acetyl hexosaminidase, leucine aminopeptidase (LAP), lactate dehydrogenase, glucose-6-phosphate dehydrogenase (g-6-PDH), and peroxidase activities were measured in the buccal mucosa of rats kept for 60 days on high-sucrose (68% of sucrose) caries-inducing diet. The findings evidence that this diet observed for 30 days results in a significant elevation of beta-galactosidase and LAP activities and in reduction of peroxidase level. After 60-day diet the examined parameters virtually did not differ from the reference characteristics (a control group kept on 68% starch diet), except elevated g-6-PDH and lowered peroxidase activities. Enzymic activity changes are adaptive and evidence changes in the metabolic processes in the buccal mucosa, that may eventuate in the development of periodontal diseases.
Vavilova
T P
TP
Malyshkina
L T
LT
Tkachenko
G I
GI
Trunilina
N I
NI
D000818:Animals; D004040:Dietary Carbohydrates / Q000008:administration & dosage*; D009061:Mouth Mucosa / Q000201:enzymology*; D051381:Rats; D013395:Sucrose / Q000008:administration & dosage*; D013997:Time Factors
D004040:Dietary Carbohydrates; D013395:Sucrose
Vliianie vysokosakharoznoĭ diety na aktivnost' fermentov slizistoĭ obolochki polosti rta krys.