[Results of specific hyposensitization in children with pollinosis].
Hyposensitization was carried out in 120 children aged 5 to 15 years with proven sensitivity to various pollen for 3 to 5 years before the start of the season. By reason of the results of intracutaneous tests 90 patients were treated with mixed pollen allergen and 30 patients with grass pollen allergen. A retrospective study was undertaken on the base of a questionnaire. Every year after the season duration and severity of symptoms as well as consumption of medicine were registered. The total success of hyposensitization amounted to 70.8% and this result varied on the one hand in dependence of the duration of disease on the other hand in dependence of the duration of treatment. A more inconvenient result was seen in those children who suffered from asthmatic symptoms exclusively compared to patients with hay fever. Local side effects resulted sporadically in 71.5% and systemic side effects in 15.7% by subcutaneous injection of depot-pollen allergen. Despite of extensive and not indifferent mode of treatment, hyposensitization should be performed in a correct way as soon as possible after exact indication.
Klinik für Kinderheikunde, Medizinischen Akademie Magdeburg.
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Schuster
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Quassem
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Sollich
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Thal
D000293:Adolescent; D001249:Asthma / Q000517:prevention & control; D002648:Child; D002675:Child, Preschool; D003233:Conjunctivitis, Allergic / Q000517:prevention & control; D003888:Desensitization, Immunologic / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D011058:Pollen / Q000276:immunology*; D006255:Rhinitis, Allergic, Seasonal / Q000517:prevention & control*; D012621:Seasons
Ergebnisse der spezifischen Hyposensibilisierung bei Kindern mit Pollinose.