Zopiclone in the treatment of sleep abnormalities in fibromyalgia.
The clinical and polysomnographical effects of zopiclone were evaluated in 41 patients with fibromyalgia in a double blind controlled study. A significant improvement was observed regarding tiredness during the day and subjective sleep complaints, but no effects on pain or stiffness were observed. The sleep structure remained unchanged during treatment. Zopiclone seems to be of value in treating the sleep complaints in patients with fibromyalgia.
Department of Rheumatology, Viborg County Hospital, Denmark.
A M
AM
Drewes
A
A
Andreasen
P
P
Jennum
K D
KD
Nielsen
D000368:Aged; D053961:Azabicyclo Compounds; D005260:Female; D005356:Fibromyalgia / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D008875:Middle Aged; D010879:Piperazines / Q000627:therapeutic use*; D012893:Sleep Wake Disorders / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D012895:Sleep, REM / Q000187:drug effects
D053961:Azabicyclo Compounds; D006993:Hypnotics and Sedatives; D010879:Piperazines; C515050:zopiclone