[Role of ventrolateral medullary area in the effect of electrical needling "Neiguan" point on improving acute myocardial ischemia in rabbits].
40 healthy rabbits were anesthetized with 20% urethane and divided into 4 groups in same number: 1) electroacupuncture group physiological saline was applied locally on the S area of the ventral surface of the medulla: 2) naloxone group, naloxone (5 mg/ml. PH 6.5-7) was applied on the S area: 3) propranolol group, propranolol (5 mg/ml. pH 7.0) was applied on the S area: 4) control group, physiological saline was applied on the S area. The state of regional myocardial ischemia of the rabbits was caused by ligating the LAD for 20 minutes. The changes of the blood pressure and the ST values of standard lead II of ECG were observed before ligating and, at 5', 10', 15', 20', 25', 30', 35', 40', 45', 50', 55' and 60' after loosening respectively. Electroacupuncture was applied on "Neiguan" points bilaterally at 10' after ligating for 60 minutes (intensity 6-8 volt, frequency 60/min). The average potential changes of the ST values of standard lead II of 5 times were used as the index to evaluate myocardial ischemia and its recovery course. The followings are the main results of our observation: There were no statistical difference, of blood pressure and the ST values between the four groups before ligation. At 10 minutes after ligation, the ST values were elevated markedly, but there were no statistical significances between the four groups.(ABSTRACT TRUNCATED AT 250 WORDS)
Department of Physiology, Hubei College of Traditional Chinese Medicine.
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Huang
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Feng
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Hu
D015669:Acupuncture Points; D000818:Animals; D003327:Coronary Disease / Q000628:therapy*; D015671:Electroacupuncture; D005260:Female; D008297:Male; D008526:Medulla Oblongata / Q000502:physiology*; D011817:Rabbits