Rh33 in two of three German siblings with D+ C+ c+ E- e+ red cells.
The proposita in a German family of three siblings has D+ C+ c+ E- e+ f+ Rh: -17,19,33,34 red cells with weak C, e, f, Rh19, and Rh34 and stronger-than-usual Rh33 expression. One sibling has D+ C+ c+ E- e+ f+ Rh:17,19,33,34 red cells with weak f and ordinary-strength Rh33, and the other sibling has D+ C+ c+ E- e+ f+ Rh:17,19,-33,34 red cells. In the absence of any further family members, the proposita's unusual phenotype suggests that she has an RoHar haplotype and a "new" Rh haplotype, provisionally named R1Lisa, that encodes Rh33, normal-strength D, weak C, weak or nondemonstrable e, Rh19, and Rh34, but not Rh17. Her Rh:33 sibling may have R1 and RoHar and her Rh:-33 sibling R1 and r haplotypes.
Natal Institute of Immunology, Durban, South Africa.
P
P
Moores
E
E
Smart
J
J
Sternberger
W
W
Schneider
D000328:Adult; D001788:Blood Grouping and Crossmatching; D003298:Coombs Test; D004912:Erythrocytes / Q000737:chemistry*; D005192:Family Health; D005260:Female; D005858:Germany / Q000208:ethnology; D006384:Hemagglutination; D006801:Humans; D012204:Rh-Hr Blood-Group System / Q000097:blood*
D012204:Rh-Hr Blood-Group System