Neovascular glaucoma, endophthalmitis and evisceration.
A retrospective study of 35 patients undergoing evisceration at Moorfields Eye Hospital, London between 1982 and 1987, revealed that 60% were known to be suffering from neovascular glaucoma, the majority as a result of a central retinal vein occlusion. 76% of these rubeotic eyes subsequently developed an endophthalmitis and required evisceration. 81% of this rubeotic, infected group were being treated with topical steroids prior to developing a suppurative keratitis and ensuing endophthalmitis. Every patient (9) with neovascular glaucoma that was debilitated (due to a variety of underlying medical conditions--4 were diabetic) developed an endophthalmitis and 78% of these were also using topical steroids. This study reveals that there may be a specific group of patients with absolute neovascular glaucoma, i.e. being debilitated and using topical steroids, who might appear to be susceptible to developing severe intraocular infection.
Murray
P I
PI
Department of Ophthalmology, University of Birmingham, U.K.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D009877:Endophthalmitis / Q000209:etiology / Q000601:surgery*; D015353:Eye Enucleation; D015818:Eye Infections, Bacterial / Q000209:etiology / Q000601:surgery*; D005260:Female; D015355:Glaucoma, Neovascular / Q000209:etiology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000150:complications / Q000188:drug therapy; D012189:Retrospective Studies; D013256:Steroids / Q000627:therapeutic use
D013256:Steroids