Real-time magnetic resonance imaging of laser heat deposition in tissue.
We applied diffusion-sensitive echo planar (Instascan) imaging to study thermal changes caused by a Nd:YAG laser. Images of phantom materials and normal rabbit brain tissue in vivo, acquired in 150 ms, every 2s, clearly showed the dynamics of temperature-related signal intensity changes in the regions irradiated by the laser.
Department of Radiology, Harvard Medical School, Boston, Massachusetts 02115.
A R
AR
Bleier
F A
FA
Jolesz
M S
MS
Cohen
R M
RM
Weisskoff
J J
JJ
Dalcanton
N
N
Higuchi
D A
DA
Feinberg
B R
BR
Rosen
R C
RC
McKinstry
S G
SG
Hushek
D000818:Animals; D001921:Brain / Q000473:pathology* / Q000601:surgery; D006358:Hot Temperature; D053685:Laser Therapy; D008279:Magnetic Resonance Imaging; D008961:Models, Structural; D011817:Rabbits