Reorganization of auditory cortex after neonatal high frequency cochlear hearing loss.
Cochleotopic representation in cortex (AI) is extensively reorganized in cats having neonatal, bilateral high frequency cochlear hearing loss. Anterior areas of AI, normally devoted to high frequencies, contain neurons which are almost all tuned to one lower frequency. This frequency corresponds, at the level of the cochlea, to the border between normal and damaged haircell regions.
Harrison
R V
RV
Hospital for Sick Children Research Institute, Toronto, Canada.
Nagasawa
A
A
Smith
D W
DW
Stanton
S
S
Mount
R J
RJ
D000583:Amikacin; D000818:Animals; D000831:Animals, Newborn; D001303:Auditory Cortex / Q000473:pathology / Q000503:physiopathology*; D002415:Cats; D003051:Cochlea / Q000293:injuries / Q000503:physiopathology; D004195:Disease Models, Animal; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology; D006316:Hearing Loss, High-Frequency / Q000473:pathology / Q000503:physiopathology*; D006319:Hearing Loss, Sensorineural / Q000473:pathology / Q000503:physiopathology
D000583:Amikacin