[13 parameters of coagulation and fibrinolysis--univariate pediatric normal values of hemostasis].
In order to establish age related univariate nonparametric tolerance regions in 74 healthy children and adolescents (age 2-18 years) undergoing elective surgery the following haemostatic parameters have been investigated: platelet count, von Willebrand factor, factor VIIIC, ristocetin-cofactor, antithrombin III, protein C fibrinogen, plasminogen, alpha-2-antiplasmin, C1-inactivator, alpha-1-antitrypsin, alpha-1-antichymotrypsin and alpha-macroglobulin. Compared to adult normal values medians of von Willebrand factor and protein C were lowered, alpha-2-antiplasmin, C1-inactivator and alpha-2-macroglobulin were elevated, whereas the medians of alpha-1-antitrypsin and alpha-1-antichymotrypsin reached the lower adult borderline. The other investigated parameters showed no difference to those of adults.
Universitäts-Kinderklinik Frankfurt/Main.
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Nowak-Göttl
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WD
Kreuz
D000293:Adolescent; D001780:Blood Coagulation Tests; D001798:Blood Proteins / Q000737:chemistry; D002648:Child; D002675:Child, Preschool; D005260:Female; D005342:Fibrinolysis; D006487:Hemostasis; D006801:Humans; D007223:Infant; D008297:Male; D010976:Platelet Count; D011446:Prospective Studies; D012016:Reference Values
D001798:Blood Proteins
13 Parameter der Gerinnung und Fibrinolyse--hämostaseologische univariate pädiatrische Normbereiche.