Estimation of ED50 or LD50 using a programmable pocket calculator.
A program is developed for estimation of median effective dose (ED50 or LD50), using the hand-held programmable pocket calculator HP41CV. The well-known Finney's algorithm of probit analysis is used. Input of data is simple, but is restricted to a maximum of 15 groups. The program structure makes use of the technique of indirect addressing for storage, and statistical register manipulation for weighted regression. The ability of the calculator to give sufficiently precise results can be exploited in other similar situations.
Institute for Research in Medical Statistics (ICMR), Ansari Nagar, New Delhi, India.
S C
SC
Mehta
D K
DK
Jain
C K
CK
Gupta
D000465:Algorithms; D007928:Lethal Dose 50; D008432:Mathematical Computing; D012984:Software; D012985:Software Design