Outcome of renal grafts after simultaneous kidney/pancreas transplantation.
Nineteen patients with endstage renal failure due to Type 1 (insulin-dependent) diabetes mellitus received simultaneous pancreas/kidney transplants using bladder drainage technique. Another group of 25 Type 1 diabetic patients received pancreas/kidney transplants by the duct occlusion technique. We observed a higher incidence of rejection episodes in the patients of the bladder drainage group than those in the duct occlusion group, 14 of 19 patients (74%) vs 7 of 25 (28%) respectively. Anti CD3 antibodies (OrthocloneR, OKT3) as a part of induction treatment was used more often in the bladder drainage group (58%) than in the control group (20%).
Nephrology Department, Klinikum Grosshadern, University of Munich, FRG.
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G
Hillebrand
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WD
Illner
D
D
Abendroth
H
H
Schneeberger
I
I
Petry
S
S
Schleibner
R
R
Landgraf
W
W
Land
D003922:Diabetes Mellitus, Type 1 / Q000601:surgery*; D003928:Diabetic Nephropathies / Q000601:surgery*; D006084:Graft Rejection; D006085:Graft Survival; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods; D007676:Kidney Failure, Chronic / Q000601:surgery*; D016030:Kidney Transplantation / Q000379:methods / Q000502:physiology*; D016035:Pancreas Transplantation / Q000379:methods / Q000502:physiology*; D016896:Treatment Outcome