Cerebellar reaggregate and explant transplants contain Bergmann glial fibers.
In mammalian cerebellum, granule cells are believed to migrate from the external germinal layer to the internal granular layer on radially oriented arrays of Bergmann glial fibers. It has been shown that similar arrays of Bergmann fibers are present in intact cerebellar transplants in rats. In the present study radial, parallel arrays have been observed in reaggregate and explant transplants in rats. These findings are consistent with the hypothesis that Bergmann fibers are involved in migration of granule cells and/or other aspects of formation of the trilaminar cortical pattern in cerebellar transplants.
Department of Anatomy and Neurobiology, University of Vermont, Burlington 05405.
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Ezerman
D000818:Animals; D016380:Brain Tissue Transplantation / Q000502:physiology*; D002449:Cell Aggregation; D002531:Cerebellum / Q000166:cytology / Q000502:physiology / Q000637:transplantation*; D016332:Fetal Tissue Transplantation / Q000502:physiology; D006085:Graft Survival; D009412:Nerve Fibers / Q000648:ultrastructure; D009457:Neuroglia / Q000166:cytology*; D009924:Organ Culture Techniques; D051381:Rats