[An immunochemical study of the interaction of human trophoblastic beta-glycoprotein with steroid and sex hormones].
Human trophoblastic beta-glycoprotein (TBG) was subjected to immunoelectrophoresis with intermediate gel containing hormones. We have observed TBG binding either with cyclopentaneperhydrophenanthrene derivatives (cholesterol, testosterone, progesterone, estradiol, estrone) or their synthetic analogs (sinestrol, diethylstilbestrol). TGB showed markedly higher affinity to estrogens than to other hormones.
Krivonosov
S K
SK
Zorin
N A
NA
Ionova
N K
NK
Kopteva
I I
II
Leutova
G V
GV
D002784:Cholesterol / Q000378:metabolism; D004347:Drug Interactions; D005260:Female; D012739:Gonadal Steroid Hormones / Q000378:metabolism*; D006728:Hormones / Q000378:metabolism*; D006801:Humans; D007123:Immunoelectrophoresis, Two-Dimensional; D008297:Male; D011268:Pregnancy-Specific beta 1-Glycoproteins / Q000378:metabolism*; D011485:Protein Binding
D012739:Gonadal Steroid Hormones; D006728:Hormones; D011268:Pregnancy-Specific beta 1-Glycoproteins; D002784:Cholesterol
Immunokhimicheskoe izuchenie vzaimodeĭstviia trofoblasticheskogo beta-glikoproteina cheloveka s steroidnymi i polovymi gormonami.