[The thrombin-antithrombin III complex ELISA test in diagnosis of surgery-induced blood coagulation activation].
In addition to measuring the routine blood coagulation parameters (Quick, PTT, TT, AT III, Fibrinogen, PLT), the Thrombin-Antithrombin III Complex (TAT) Test was performed preoperatively on 20 patients treated because of nodular goiter in the euthyreoid state and ten patients with symptomatic cholecystolithiasis. While there were no changes in the routine blood coagulation parameters, significant alterations of the TAT occurred in both patient groups. This indicates that TAT makes operation-induced activation of the blood coagulation system, which is impossible by just measuring the routine blood coagulation parameters alone, detectable.
Chirurgische Klinik Ruhruniversität am St. Josef-Hospital, Bochum.
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M
Kemen
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Sperling
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Mumme
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Zumtobel
D000328:Adult; D000990:Antithrombin III / Q000032:analysis*; D001780:Blood Coagulation Tests; D002763:Cholecystectomy; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008297:Male; D010447:Peptide Hydrolases / Q000032:analysis*; D011183:Postoperative Complications / Q000097:blood* / Q000175:diagnosis; D013927:Thrombosis / Q000097:blood* / Q000175:diagnosis; D013965:Thyroidectomy
C046193:antithrombin III-protease complex; D000990:Antithrombin III; D010447:Peptide Hydrolases
Der Thrombin-Antithrombin-III-Komplex-ELISA-Test in der Diagnostik der operationsbedingten Gerinnungsaktivierung.