Age-related changes in the human lens. Clinical assessment of age-related changes in the human lens.
We compared two methods for assessing changes in the human lens associated with age. The first is a subjective method for quantifying light absorption by the lens. It is useful for determining the functional effect of age-related increases in lens density, especially for short-wavelength light. The second method objectively and rapidly measures the increase in scattered light with increasing lens density. These two methods accurately measured age-related changes and were highly correlated with each other (r = 0.72, P less than 0.001). Both methods were evaluated in a population of normal eyes, eyes with ocular hypertension, and eyes with primary open angle glaucoma. We found ni significant differences among these groups with either method.
Sample
P A
PA
Department of Ophthalmology, University of California, San Diego.
Quirante
J S
JS
Weinreb
R N
RN
D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D002386:Cataract / Q000503:physiopathology; D005902:Glaucoma, Open-Angle / Q000503:physiopathology; D006801:Humans; D007908:Lens, Crystalline / Q000503:physiopathology*; D008875:Middle Aged; D009798:Ocular Hypertension / Q000503:physiopathology; D010775:Photic Stimulation; D011897:Random Allocation; D015203:Reproducibility of Results; D014787:Vision Tests / Q000379:methods