[Activation of expression of two immunoglobulin SN-genes in the American mink with Aleutian disease].
110 ranch-raised minks were injected with the Aleutian disease virus. Allotypes of constant regions of gamma-heavy chains of the mink immunoglobulins secreted have been analysed during 3 months. Activation of the expression of two markers (H3 and/or H4) up to minor or to nominal level (above 200 micrograms/ml) was observed. No such enhancement of expression of two other allotypes (H6 and H8) was found. The results suggest that the expression of two mink immunoglobulin CH genes induced by viral infection has allotype-specific regulation.
I I
II
Fomicheva
D K
DK
Tsertsvadze
O Iu
OIu
Volkova
N A
NA
Popova
S I
SI
Smirnykh
N A
NA
Kisteneva
KuznetsovKN
V F
VF
Kudashev
Iu D
IuD
Kaveshnikov
D000453:Aleutian Mink Disease / Q000235:genetics* / Q000276:immunology; D000818:Animals; D015870:Gene Expression; D005803:Genes, Immunoglobulin; D005819:Genetic Markers; D007074:Immunoglobulin G / Q000097:blood; D007129:Immunoglobulin Gm Allotypes; D008907:Mink / Q000235:genetics* / Q000276:immunology; D010641:Phenotype; D011110:Polymorphism, Genetic
D005819:Genetic Markers; D007074:Immunoglobulin G; D007129:Immunoglobulin Gm Allotypes
Aktivatsiia ékspressii dvukh SN-genov immunoglobulinov amerikanskoĭ norki pri aleutskoĭ bolezni.