Fatal cardiopulmonary complications in children treated with ventriculoatrial shunts.
During the years from 1965 to 1986, 716 children underwent a total of 2065 shunt procedures in our department. Of these, 1298 were ventriculoatrial (VA). Until 1979, Pudenz VA shunts were almost exclusively used as the primary procedure as well as in revisions. Since 1980, mini-Holter VA shunts have been implanted as a second choice, usually in cases with repeated distal failure in ventriculoperitoneal (VP) shunts. Observation time for children with VA shunts is therefore from 10 to 23 years for the great majority. The cumulative death rate for all patients is 24% (175/716), 9% (64/716) being tumor patients who eventually died as a result of their neoplasm. Most of the other deaths were caused by shunt infection or occurred in a group of children where shunts had been implanted for palliative reasons and where follow-up was only sporadic. Among the 450 children with VA shunts, 15 fatal complications occurred that were directly related to the atrial catheter, resulting in an accumulated incidence of 3% of such serious side effects from VA shunting. Three of these 15 fatal cases presented with nonspecific signs of cardiopulmonary failure following 10-21 years' shunting, and they died from irreversible pulmonary hypertension within a few months. A fourth case of late cor pulmonale has done unexpectedly well and has improved considerably while receiving anticoagulant therapy for over a period of 3 years.
Department of Neurosurgery, National Hospital, University of Oslo, Norway.
T
T
Lundar
I A
IA
Langmoen
K H
KH
Hovind
D000293:Adolescent; D000328:Adult; D002423:Cause of Death; D002557:Cerebrospinal Fluid Shunts / Q000295:instrumentation* / Q000401:mortality; D002648:Child; D002675:Child, Preschool; D005260:Female; D006325:Heart Atria; D006333:Heart Failure / Q000401:mortality*; D006801:Humans; D006849:Hydrocephalus / Q000401:mortality / Q000601:surgery*; D008297:Male; D011183:Postoperative Complications / Q000401:mortality*; D011660:Pulmonary Heart Disease / Q000401:mortality; D012131:Respiratory Insufficiency / Q000401:mortality*; D012307:Risk Factors; D018805:Sepsis / Q000401:mortality