Novel HLA-DR2 and -DR3 haplotypes among Norwegian Caucasians.
In the Northern European population, all DR2 haplotypes encoded by DRB1*1501 have previously been found to carry the DQA1*0102 and DQB1*0602 alleles, and DR3 haplotypes have been found to carry the DQA1*0501 and DQB1*0201 alleles. Here we report a novel recombinant DR2 haplotype carrying the DRB1*1501, DQA1*0102 and DQB1*0603 alleles as well as a novel recombinant DR3 haplotype carrying the DRB1*0301, DRB3*0101, DQA1*0102 and DQB1*0602 alleles.
Ronningen
K S
KS
Institute of Transplantation Immunology, National Hospital, Oslo, Norway.
Spurkland
A
A
Iwe
T
T
Sollid
L M
LM
Vartdal
F
F
Thorsby
E
E
D000483:Alleles; D001483:Base Sequence; D005260:Female; D005787:Gene Frequency; D005802:Genes, MHC Class II; D015802:HLA-DR2 Antigen / Q000235:genetics*; D015803:HLA-DR3 Antigen / Q000235:genetics*; D006239:Haplotypes; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D009664:Norway; D010375:Pedigree; D011995:Recombination, Genetic; D044465:White People / Q000235:genetics*
D015802:HLA-DR2 Antigen; D015803:HLA-DR3 Antigen