Immunological aspects of corneal graft rejection.
Immunological graft rejection is a major cause of corneal graft failure. HLA class I and II antigens are expressed by various cells within the cornea and during sensitisation of the recipient donor antigens appear to be presented by both donor and recipient antigen presenting cells. Certain donor and host factors have been shown to influence the incidence of corneal graft rejection, and the manipulation of these factors is discussed.
Prendergast
D G
DG
Department of Ophthalmology, Bristol Eye Hospital, U.K.
Easty
D L
DL
D016039:Corneal Transplantation / Q000276:immunology*; D006084:Graft Rejection / Q000276:immunology*; D006680:HLA Antigens / Q000276:immunology; D006801:Humans; D007165:Immunosuppression Therapy; D012307:Risk Factors; D016896:Treatment Outcome
D006680:HLA Antigens