Leukemia cutis in acute myelomonocytic leukemia: infiltration to minor traumas and scars.
We describe a patient with acute myelomonocytic leukemia who demonstrated leukemic cell infiltration to scratched wounds and scars from trauma. A 65-year-old Japanese woman developed low grade fever, headache and exanthema. Hematology testing disclosed leukocytosis of 95,600/mm3 with 65% monocytes and 9% blast cells. Infiltrated erythema and nodules were disseminated over most of her body. Moreover, linear scratched wounds and traumatic scars were indurated. Skin biopsy showed dense atypical mononuclear cell infiltration with monocytic characteristics. We discuss the possible reasons for the infiltration of leukemia cells into the wounds and scars from trauma.
Koizumi
H
H
Department of Dermatology, Hokkaido University School of Medicine, Sapporo, Japan.
Kumakiri
M
M
Ishizuka
M
M
Ohkawara
A
A
Okabe
S
S
D000368:Aged; D002921:Cicatrix / Q000473:pathology*; D005260:Female; D006801:Humans; D015479:Leukemia, Myelomonocytic, Acute / Q000473:pathology*; D007964:Leukocytosis / Q000473:pathology; D012867:Skin / Q000293:injuries* / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*