Use of third-generation cephalosporins. Streptococci.
The third-generation cephalosporins are highly active against nonenterococcal streptococci. The subgroup of ceftizoxime, ceftriaxone, and cefotaxime are similar to penicillin in their activities by weight; and the drug with the longest half-life, ceftriaxone, offers the potential for home therapy for selected patients with endocarditis.
Division of Infectious Diseases and International Health, Duke University Medical Center, Durham, North Carolina.
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Durack
D000328:Adult; D000368:Aged; D000818:Animals; D002443:Ceftriaxone / Q000627:therapeutic use; D002511:Cephalosporins / Q000494:pharmacology / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004698:Endocarditis, Subacute Bacterial / Q000188:drug therapy; D005260:Female; D006801:Humans; D008297:Male; D013290:Streptococcal Infections / Q000188:drug therapy*; D013291:Streptococcus / Q000187:drug effects
D002511:Cephalosporins; D002443:Ceftriaxone