Aureobasidins, new antifungal antibiotics. Taxonomy, fermentation, isolation, and properties.
Aureobasidins A to R were isolated from the fermentation broth of Aureobasidium pullulans R106. Aureobasidins are cyclic depsipeptide antibiotics with MW's ranging from 1.070 to 1,148. Aureobasidins showed high in vitro antifungal activity against Candida albicans.
Takesako
K
K
Biotechnology Research Laboratories, Takara Shuzo Co., Ltd., Shiga, Japan.
Ikai
K
K
Haruna
F
F
Endo
M
M
Shimanaka
K
K
Sono
E
E
Nakamura
T
T
Kato
I
I
Yamaguchi
H
H
D000935:Antifungal Agents / Q000302:isolation & purification* / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D005285:Fermentation; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi / Q000737:chemistry*
D000935:Antifungal Agents