CT scan abnormalities and outcome of chronic schizophrenia.
The authors evaluated the relationship between brain morphological characteristics assessed by means of computerized tomography and the 2-year clinical and social outcomes of 18 patients with chronic schizophrenia. Cerebral structural abnormalities, especially cortical atrophy, were associated with a poorer outcome in several areas of clinical and social functioning.
Schizophrenia Research Center, University of Milan, Italy.
A
A
Vita
M
M
Dieci
G M
GM
Giobbio
P
P
Azzone
M
M
Garbarini
E
E
Sacchetti
B M
BM
Cesana
C L
CL
Cazzullo
D000328:Adult; D001284:Atrophy / Q000473:pathology; D001921:Brain / Q000033:anatomy & histology* / Q000000981:diagnostic imaging / Q000473:pathology; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012559:Schizophrenia / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D012720:Severity of Illness Index; D012917:Social Adjustment; D014057:Tomography, X-Ray Computed