Acanthosis nigricans.
Acanthosis nigricans (AN) is a dermopathy with a distinctive appearance that facilitates its diagnosis. Although an external condition, it is associated with a wide variety of less obvious internal conditions, either benign or malignant. Insulin resistance figures prominently in its benign associations and plays a primary role in its development. The development of AN in malignant conditions remains to be explained. AN rarely requires treatment, although the underlying condition usually does.
Emory University School of Medicine, Atlanta, GA.
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Rogers
D000052:Acanthosis Nigricans / Q000150:complications / Q000473:pathology / Q000628:therapy; D006801:Humans