The most frequently lost allelic site in human renal cell carcinoma (D3F15S2) on the short arm of chromosome 3 has homologous sequences on rat chromosome 8.
It has previously been shown that human chromosome 3 has banding homology to rat chromosome 8. We have previously isolated a cDNA from the D3F15S2 region and designated the gene as RIK. In the present study, we localized the homolog of this gene to rat chromosome 8.
Erlandsson
R
R
Department of Tumor Biology, Karolinska Institutet, Stockholm, Sweden.
Szpirer
J
J
Islam
M Q
MQ
Boldog
F
F
Klein
G
G
Ingvarsson
S
S
D000483:Alleles; D000818:Animals; D002292:Carcinoma, Renal Cell / Q000235:genetics*; D002460:Cell Line; D002871:Chromosome Banding; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D002893:Chromosomes, Human, Pair 3; D015342:DNA Probes; D006801:Humans; D006822:Hybrid Cells / Q000166:cytology; D007680:Kidney Neoplasms / Q000235:genetics*; D051379:Mice; D051381:Rats; D011919:Rats, Inbred Strains / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid
D015342:DNA Probes