[Hemodynamics of the lesser circulation in patients with ischemic heart disease during acute obsidan test].
During acute obsidan testing, the hemodynamics was evaluated in the pulmonary circuit and right heart cavities of 60 patients with Functional Classes III-IV exertional angina pectoris, by using two-dimensional and Doppler echocardiographies of the pulmonary artery. According to the left ventricular myocardial volume/mass ratio, the patients were divided into 3 morphofunctional types of coronary heart disease (CHD). All the patients were found to have diminished contractility and pump function in the left heart along with moderately elevated blood pressure in the left heart and compensatory hyperfunction in the right heart, which are largely evident in the hypertrophic morphofunctional type of CHD. The degree of pulmonary hypertension was related to the severity of left ventricular dysfunction, whereas in the dilated type it was associated with its contractile disorders. In patients with the dilated and mixed types of CHD, obsidan caused a marked decrease in pulmonary hypertension, while in those with hypertrophic CHD it promoted its slight increase.
Vorob'ev
L P
LP
Maev
I V
IV
Kaziulin
A N
AN
D000293:Adolescent; D000328:Adult; D003327:Coronary Disease / Q000503:physiopathology*; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D008875:Middle Aged; D011433:Propranolol / Q000494:pharmacology*; D011652:Pulmonary Circulation / Q000187:drug effects / Q000502:physiology*; D016277:Ventricular Function, Left / Q000187:drug effects / Q000502:physiology*
D011433:Propranolol
Gemodinamika malogo kruga krovoobrashcheniia u bol'nykh ishemicheskoĭ bolezn'iu serdtsa v usloviiakh ostroĭ proby s obzidanom.