[Ventricle-vessels relationship in aspects of hypertension].
The diagnostics of the ventricle-vessel relations in arterial hypertension is significant in particular for advanced stages. Under the aspect to regard the cardiac contraction in form of a model as temporarily varying elastance of the volume invasively (P-measurement, V-measurement, preload alteration via balloon in the inferior vena cava) relations of the ventricular pressure volume (ESPVR, EDPVR) and system-arterial ones in form of the effective arterial elastance can be established. Additionally calculated functional curves give separated information concerning the influence of preload, afterload and contractility on the stroke work. Thus a comprehensive statement concerning the cardiovascular function and a basis for valuable therapeutic effects is worked out. Several references result for advanced stages of the arterial hypertension with hypertrophied heart. The systolic function remains normal for a long time. Diastolically the increasingly disturbed relaxation with pathological preload is found. The relation stroke work-afterload is no more in the optimum region and can further be deteriorated by vasodilation. Whether or not, however, this relation has the same relevance for all clinical questions, remains open. Is the stroke work really that parameter which shall be optimized therapeutically?
Abteilung für Kardiologie, Fakultät für Medizin, Universität Rostock.
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Urbaszek
D001794:Blood Pressure; D002311:Cardiomyopathy, Dilated / Q000503:physiopathology; D002312:Cardiomyopathy, Hypertrophic / Q000503:physiopathology; D002319:Cardiovascular System / Q000503:physiopathology*; D006334:Heart Function Tests; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D013318:Stroke Volume; D016276:Ventricular Function
Ventrikel-Gefäss-Beziehungen unter dem Aspekt der Hypertonie.