Interleukin-2 receptors on rat eosinophils in adjuvant arthritis.
Monoclonal antibodies specific for the interleukin-2 receptor (IL-2R) have been used to demonstrate by immunohistochemical methods the presence of IL-2R on eosinophils as well as on lymphocytes in lymphoid tissue taken from rats with adjuvant arthritis. Evidence is presented which suggests that the IL-2R on eosinophils may have been induced by the disease process.
Lilly Research Centre Limited, Eli Lilly & Co., Windlesham, Surrey, U.K.
S C
SC
Meacock
D R
DR
Brandon
W
W
Smith
D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology; D001169:Arthritis, Experimental / Q000276:immunology*; D004804:Eosinophils / Q000276:immunology*; D007124:Immunoenzyme Techniques; D008198:Lymph Nodes / Q000276:immunology; D008214:Lymphocytes / Q000276:immunology; D051381:Rats; D015375:Receptors, Interleukin-2 / Q000032:analysis*
D000911:Antibodies, Monoclonal; D015375:Receptors, Interleukin-2