Selective involvement of the spinal trigeminal nucleus in the conditioned nictitating membrane reflex of the rabbit.
These experiments were performed to test the hypothesis that a region associated with the trigeminal nuclear complex is selectively involved in mediating the classically conditioned nictitating membrane reflex in the rabbit. Microinjections of Lidocaine were used to produce a temporary, localized block of neural activity following the conditioning of the reflex using a standard tone/air puff-paired stimulus paradigm. Data indicate that the injection of Lidocaine at the medial pars oralis/reticular formation junction results in a selective suppression of the conditioned reflex.
Bracha
V
V
Division of Neurobiology, Barrow Neurological Institute, Phoenix, AZ 85013.
Wu
J Z
JZ
Cartwright
S
S
Bloedel
J R
JR
D000818:Animals; D003214:Conditioning, Classical / Q000187:drug effects / Q000502:physiology*; D008012:Lidocaine / Q000494:pharmacology; D008845:Microinjections; D009541:Nictitating Membrane / Q000502:physiology*; D010775:Photic Stimulation; D010812:Physical Stimulation; D011817:Rabbits; D014279:Trigeminal Nucleus, Spinal / Q000502:physiology*
D008012:Lidocaine