Biology of cancer and aging.
The greatest risk factor for cancer is aging. Human cancer incidence increases exponentially with advancing age. Cancer growth rate and potential for metastatic spread may be influenced by age-specific change in host response. Because cancer and aging are, thus, inextricably linked, the American Cancer Society should encourage submission of research proposals that address the mechanisms of aging and how aging alters cancer development.
University of Kansas Medical Center, Kansas City 66103.
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Holmes
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Wilson
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Blesch
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Kaesberg
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Miller
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Sprott
D000367:Age Factors; D000368:Aged; D000375:Aging / Q000502:physiology*; D006801:Humans; D015994:Incidence; D008136:Longevity; D009369:Neoplasms / Q000453:epidemiology / Q000503:physiopathology*