Proximal gastric vagotomy. A comparative study between the standard technique and the extended technique associated with denervation of the greater curvature.
Forty-six patients in the postoperative period of proximal gastric vagotomy (PGV) for duodenal ulcer (DU) were studied comparatively to verify whether the dividing of the gastroepiploic nerves (Rosati's maneuver) can reduce or not the occurrence of recurrent ulcer as it was proposed. Twenty-one patients who underwent PGV associated with Rosati's maneuver (PGV-R) were compared to 25 after standard PGV (PGV-S), according to several criteria: (1) clinical evaluation; (2) pre and postoperative basal and pentagastrin-stimulated gastric acidity; (3) postoperative basal and pentagastrin-stimulated serum pepsinogen; (4) postoperative basal and sham feeding-stimulated serum gastrin; (5) postoperative endoscopy; (6) endoscopic Congo red test. Both groups were similar (P greater than 0.05) as to age, sex, levels of preoperative gastric acidity and had a 24.4 month average follow-up (12 to 58 months). There has been no significant difference between the techniques studied as to clinical, secretory, morphological or hormonal gastric tests, although PGV-R proved more effective in reducing basal gastric acidity than PGV-S (P less than 0.05). We concluded that Rosati's maneuver does not improve the results obtained with PGV, although it provided greater reduction of basal gastric acidity than PGV-S.
D'Albuquerque
L A
LA
Department of Gastroenterology, Hospital das Clínicas, University of Saõ Paulo, College of Medicine, Brazil.
Gama-Rodrigues
J
J
De Miranda
M F
MF
Genzini
T
T
Sakai
P
P
Laudanna
A A
AA
Pinotti
H W
HW
D000328:Adult; D003224:Congo Red; D004381:Duodenal Ulcer / Q000517:prevention & control / Q000601:surgery*; D005260:Female; D005744:Gastric Acid / Q000378:metabolism; D005755:Gastrins / Q000097:blood; D005773:Gastroscopy; D006801:Humans; D015994:Incidence; D008022:Ligaments / Q000294:innervation; D008297:Male; D010435:Pepsinogens / Q000097:blood; D011706:Pyloric Antrum / Q000294:innervation; D012008:Recurrence; D014629:Vagotomy, Proximal Gastric / Q000379:methods*
D005755:Gastrins; D010435:Pepsinogens; D003224:Congo Red