NPC 15669 enhances survival and reverses leukopenia in endotoxin-treated mice.
Nova Pharmaceutical Corporation, Baltimore, MD 21224.
L
L
Noronha-Blob
V C
VC
Lowe
M
M
Weitzberg
R M
RM
Burch
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D004731:Endotoxins / Q000633:toxicity*; D007930:Leucine / Q000031:analogs & derivatives* / Q000494:pharmacology; D007962:Leukocytes / Q000187:drug effects; D007970:Leukopenia / Q000097:blood / Q000139:chemically induced / Q000188:drug therapy*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D012772:Shock, Septic / Q000097:blood / Q000188:drug therapy
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004731:Endotoxins; C071244:N-(9H-(2,7-dimethylfluoren-9-ylmethoxy)carbonyl)leucine; D007930:Leucine