Multiple and complex abnormalities in a case of alveolar soft-part sarcoma.
Chromosomal analysis of two pulmonary metastases from a 25-year-old male with alveolar soft-part sarcoma of the right lower extremity revealed multiple and complex chromosomal abnormalities. The rearrangements included deletions and translocations affecting chromosomes 1, 2, 3, 10, 11, 14, 15, and 16. Trisomy of chromosome 12 and loss of chromosome 17 was also observed.
Cancer Center, Southwest Biomedical Research Institute, Scottsdale, AZ 85251.
C
C
Sreekantaiah
F P
FP
Li
N
N
Weidner
A A
AA
Sandberg
D000328:Adult; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D002872:Chromosome Deletion; D006801:Humans; D007621:Karyotyping; D008175:Lung Neoplasms / Q000235:genetics / Q000473:pathology / Q000556:secondary*; D008297:Male; D012509:Sarcoma / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D014178:Translocation, Genetic; D014314:Trisomy