[A case of malignant hemangioendothelioma effectively treated with intra-arterial continuous infusion of interleukin-2].
A case of Malignant Hemangioendothelioma (MHE) effectively treated with intra-arterial continuous infusion of recombinant interleukin-2 (rIL-2) was experienced. The Pt, a 82-year-old women, presented herself in our hospital with a complaint of the tumor in right-frontal region. Based on clinical and pathological findings, the Pt, was diagnosed as MHE. Increase of LAK (Lymphokine activated killer cell) activity was observed during treatment with intra-arterial continuous infusion of rIL-2. In addition, decrease of tumor was started when LAK activity showed high value. We mainly discussed about treatments for MHE and mechanism of these therapies by use of data of this case and other autho's papers.
Fujioka
A
A
Department of Dermatology, Choshi General City Hospital.
Sezai
Y
Y
D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006390:Hemangioendothelioma / Q000628:therapy*; D006801:Humans; D007261:Infusions, Intra-Arterial; D007376:Interleukin-2 / Q000008:administration & dosage / Q000627:therapeutic use*; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000627:therapeutic use; D012074:Remission Induction; D012535:Scalp; D012878:Skin Neoplasms / Q000628:therapy*
D007376:Interleukin-2; D011994:Recombinant Proteins