Distribution of leucocyte antigens in Icelandic horses affected with summer eczema compared to non-affected horses.
Three hundred and three horses, exported from Iceland to Norway, Sweden, Denmark, Switzerland or Germany were tested for their distribution of leucocyte antigens. One hundred and thirty-six horses were affected with summer eczema. The panel of sera recognised the internationally accepted ELA-specificities A 1 to A10, and the nine work shop specificities W 11 to W 15 and W 18 to W 21. Also, some local specificities, characterised in Switzerland (Be I, Be III, Be 8, Be 25, Be 26, Be 27), and two non major histocompatibility complex (MHC)-linked antigens (Ely 1:1, Ely 2) were included. Only one antigen, Be 8, gave a statistically significant difference in distribution between the two populations: Relative risk = 2.5, x2 = 10.11, corrected P less than 0.01.
Norwegian College of Veterinary Medicine, Department of Microbiology and Immunology, Oslo.
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S
Halldórsdóttir
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S
Lazary
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Gunnarsson
H J
HJ
Larsen
D000818:Animals; D002519:Ceratopogonidae / Q000276:immunology*; D003876:Dermatitis, Atopic / Q000235:genetics / Q000276:immunology / Q000662:veterinary*; D005260:Female; D005787:Gene Frequency; D020022:Genetic Predisposition to Disease; D006649:Histocompatibility Antigens / Q000097:blood*; D006734:Horse Diseases / Q000235:genetics / Q000276:immunology*; D006736:Horses; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D012621:Seasons
D006649:Histocompatibility Antigens