Occupational asthma due to ethylene diamine.
We report a case of bronchial asthma due to ethylene diamine in a chemical worker. The typical relationship with work exposure was elicited from the occupational history and serial peak flow measurements. A late dual asthmatic reaction was seen in bronchial provocation test with ethylene diamine. Bronchial hyper-responsiveness to isopropyly alcohol and histamine was observed and was likely to be the result rather than a predisposing factor for the development of occupational asthma. Amines are a powerful group of small molecular weight asthmatogens that are commonly used in various types of industries locally and should be recognised in the clinical evaluation of workers with asthma.
Department of Community, Occupational & Family Medicine, National University of Singapore.
T P
TP
Ng
H S
HS
Lee
F Y
FY
Lee
Y T
YT
Wang
V L
VL
Tay
K T
KT
Tan
D000328:Adult; D001249:Asthma / Q000139:chemically induced* / Q000175:diagnosis; D001985:Bronchial Provocation Tests; D002617:Chemical Industry; D005029:Ethylenediamines / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009784:Occupational Diseases / Q000139:chemically induced* / Q000175:diagnosis; D012123:Pulmonary Ventilation
D005029:Ethylenediamines; C031234:ethylenediamine