[Characteristics of peptide preparations obtained during enzymatic hydrolysis and ultrafiltration of milk proteins for use in specialized nutrition products].
+Ultrafiltrated bovine milk proteins with whey protein/casein ratios 20/80, 60/40 and 97/3 were subjected to pancreatin hydrolysis, and the hydrolysates obtained were fractionated to high- and low-molecular weight (LMW) fractions by means of ultrafiltration. The preparations obtained were characterized according to routine physico-chemical indices, amino-nitrogen content, amino acids score, molecular weight distribution, and concentration of precipitating milk antigens. The capacity of LMW fractions for inducing oral anaphylactic sensitization in guinea pig and for changing its susceptibility to histamine LD50 was studied. The conclusion has been made that LMW preparations with whey/casein ratios 20/80 and 60/40 could be effectively used in specialized formulae intended for nutrition of allergic children and adults, nursing women, and also for enteral nutrition.
Gmoshinskiĭ
I V
IV
Kruglik
V I
VI
Samenkova
N F
NF
Krzhechkovskaia
V V
VV
Zorin
S N
SN
Mazo
V K
VK
D000328:Adult; D000596:Amino Acids / Q000737:chemistry; D000818:Animals; D002648:Child; D004195:Disease Models, Animal; D005512:Food Hypersensitivity / Q000178:diet therapy*; D006168:Guinea Pigs; D006801:Humans; D006868:Hydrolysis; D008894:Milk Proteins / Q000737:chemistry* / Q000276:immunology / Q000627:therapeutic use; D010194:Pancreatin / Q000494:pharmacology; D010455:Peptides / Q000737:chemistry* / Q000276:immunology / Q000627:therapeutic use; D014462:Ultrafiltration
D000596:Amino Acids; D008894:Milk Proteins; D010455:Peptides; D010194:Pancreatin
Kharakteristika peptidnykh preparatov, poluchennykh pri fermentativnom gidrolize i ul'trafil'tratsii belkov moloka, prednaznachennykh dlia ispol'zovaniia v spetsializirovannykh produktakh pitaniia.