Platelet indices: intra-individual variation in pre- and post-menopausal females.
Blood platelet counts and mean platelet volumes were determined at weekly intervals for eight weeks in 13 pre-menopausal and 11 post-menopausal females. Samples were analysed exactly two hours after blood collection on a Coulter S plus VTM particle counter. Pre-menopausal platelet counts were slightly higher than post-menopausal counts at each week, but the count was not affected by the menstrual cycle, intra-individual variation showing mean coefficients of variation (CV) of 7.4% and 5.2% respectively. The mean platelet volume was similar in pre- and post-menopausal groups at each week and showed little variability over time (mean CV 2.7% and 3.3%, respectively). Platelet parameters show little variability over time in either group and with no cyclical effects of menstruation apparent.
Department of Pathology, Wellington School of Medicine, New Zealand.
J M
JM
Carter
R W
RW
Siebers
P J
PJ
Wakem
P J
PJ
Waken
D001792:Blood Platelets / Q000166:cytology*; D005260:Female; D006801:Humans; D008593:Menopause / Q000097:blood*; D010976:Platelet Count