The histologic characteristics of the core of the fissula ante fenestram.
In earlier studies of perilymphatic fistulae, we described their histologic criteria and the clinical criteria for the identification and prediction of patencies of the labyrinth capsule related to disorders of hearing and balance. These patencies were either of the fissula ante fenestram or of the round window niche-posterior canal ampulla fissure. The permeability of the fibrous core of a patent fissula ante fenestram has been questioned, authors of some earlier articles arguing that the tissue is loose, others that it is dense. This study demonstrates loose fibrous and cellular structure in the fissula's tract, dense collagen at the circumference. The loose arrangement of tissue suggests that fluid can pass through this patency, and it appears similar to that of the spiral ligament which has been shown to contain perilymph by way of intercellular communications with the perilymphatic space.
Department of Otolaryngology, Bowman Gray School of Medicine, Winston-Salem, North Carolina.
R I
RI
Kohut
R
R
Hinojosa
J H
JH
Ryu
D004432:Ear, Middle / Q000473:pathology*; D006801:Humans; D007759:Labyrinth Diseases / Q000473:pathology*; D010498:Perilymph / Q000502:physiology; D012405:Round Window, Ear / Q000473:pathology; D014722:Vestibule, Labyrinth / Q000473:pathology*