Endoscopic injection of alcohol to stop peptic ulcer hemorrhage. Experience with 115 cases.
In a period of 33 months, we performed endoscopic injection with pure alcohol (PA) to try to stop peptic ulcer hemorrhage in 115 patients. The sex ratio (M/F) was 104/11. The average age was 59.5 +/- 1.5 years (mean +/- SEM). Sixty-two patients (53.9%) were in shock before endoscopic injection. Thirty-three (28.7%) had spurting hemorrhage, 31 (27%) oozing hemorrhage, and 51 (44.3%) nonbleeding visible vessels (NBVV). We obtained initial success in 92 patients (80%). Rebleeding episodes occurred in 7 patients (7.6%) within 7 days of endoscopic injection. Five of those who rebled received a second injection with PA and bleeding stopped in three of them. In 88 (76.5%) patients, therapy was ultimately successful. The duration of hospitalization was 5.1 +/- 0.6 days (mean +/- SEM). The total volume of blood transfused was 1450 +/- 192 ml (mean +/- SEM). We conclude that endoscopic injection is an inexpensive, convenient, and effective means for arresting peptic ulcer hemorrhage. It can be used as the first therapeutic approach.
Department of Medicine, Veterans General Hospital, Taipei, Taiwan, R.O.C.
H J
HJ
Lin
F Y
FY
Lee
C H
CH
Lee
S D
SD
Lee
D004630:Emergencies; D000431:Ethanol / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D005773:Gastroscopy; D006489:Hemostatic Techniques; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D010438:Peptic Ulcer Hemorrhage / Q000628:therapy*; D012008:Recurrence; D012737:Sex Factors; D012769:Shock / Q000150:complications
D000431:Ethanol