[Pharmacological correction of disorders of antithrombogenic properties of the vascular wall in patients with arteriosclerosis of the lower extremities].
Examined were 156 patients (all the men) at the age of from 41 to 76 years with obliterative atherosclerosis of the arteries of the lower extremities. The antithrombogenic properties of a vascular wall were studied with a use of the functional vascular test with arteriovenous occlusion (cuff test). Reduction of the antithrombogenic properties of a vascular wall, ++anti-aggregative, anticoagulative and fibrinolytic activity as compared with those in normal subjects was revealed. For correction of disorders in antithrombogenic activity of a vascular wall, the administration of a complex of hemostatically active preparations (trental, phytin, glutaminic acid) is recommended.
Adamchik
A S
AS
Kokhan
E P
EP
Grishin
G P
GP
D000328:Adult; D000368:Aged; D001162:Arteriosclerosis Obliterans / Q000097:blood*; D005263:Femoral Artery / Q000503:physiopathology; D006801:Humans; D007083:Iliac Artery / Q000503:physiopathology; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects* / Q000502:physiology; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage; D013927:Thrombosis / Q000517:prevention & control*
D010975:Platelet Aggregation Inhibitors
Farmakologicheskaia korrektsiia narusheniĭ antithrombogennykh svoĭstv stenki sosudov u bol'nykh s aterosklerozom arteriĭ nizhnikh konechnosteĭ.