Embolic stroke following carotid radiation angiopathy demonstrated with I-123 IMP brain SPECT.
Radiation angiopathy was developed by the process of accelerated atherosclerosis at the site of irradiation. The case of a 44-year-old man with right hemiparesis showing a high signal intensity in the left semioval center on MRI and a defect in the left temporo-parietal area with subsequent filling-in with I-123 IMP brain SPECT is reported. Digital subtraction angiography showed typical radiation angiopathy with ulceration in the left common carotid artery. Twenty-four years previously, he underwent curative irradiation of a neck mass that revealed Hodgkin's disease by biopsy. The emboli formed at the site of radiation-induced angiopathy and caused cerebral infarction. The perfusion abnormality in the territory of the embolic artery was detected by I-123 IMP SPECT. Long-term survivors of neck irradiation are at high risk for the development of carotid arterial disease and should be watched carefully.
Hayashida
K
K
Department of Diagnostic Radiology, National Cardiovascular Center, Osaka, Japan.
Nishimura
T
T
Imakita
S
S
Kumita
S
S
Uehara
T
T
Hamada
S
S
D000328:Adult; D000662:Amphetamines; D001921:Brain / Q000000981:diagnostic imaging*; D002340:Carotid Artery Diseases / Q000209:etiology*; D002544:Cerebral Infarction / Q000000981:diagnostic imaging / Q000209:etiology*; D006258:Head and Neck Neoplasms / Q000532:radiotherapy; D006689:Hodgkin Disease / Q000532:radiotherapy; D006801:Humans; D002537:Intracranial Arteriosclerosis / Q000209:etiology*; D007457:Iodine Radioisotopes; D020367:Iofetamine; D008297:Male; D011878:Radiotherapy / Q000009:adverse effects*; D013997:Time Factors; D015899:Tomography, Emission-Computed, Single-Photon
D000662:Amphetamines; D007457:Iodine Radioisotopes; D020367:Iofetamine