Occupational asthma due to ethylene diamine.
We report a case of bronchial asthma due to ethylene diamine in a chemical worker. The typical relationship with work exposure was elicited from the occupational history and serial peak flow measurements. A late dual asthmatic reaction was seen in bronchial provocation test with ethylene diamine. Bronchial hyper-responsiveness to isopropyly alcohol and histamine was observed and was likely to be the result rather than a predisposing factor for the development of occupational asthma. Amines are a powerful group of small molecular weight asthmatogens that are commonly used in various types of industries locally and should be recognised in the clinical evaluation of workers with asthma.
Ng
T P
TP
Department of Community, Occupational & Family Medicine, National University of Singapore.
Lee
H S
HS
Lee
F Y
FY
Wang
Y T
YT
Tay
V L
VL
Tan
K T
KT
D000328:Adult; D001249:Asthma / Q000139:chemically induced* / Q000175:diagnosis; D001985:Bronchial Provocation Tests; D002617:Chemical Industry; D005029:Ethylenediamines / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009784:Occupational Diseases / Q000139:chemically induced* / Q000175:diagnosis; D012123:Pulmonary Ventilation
D005029:Ethylenediamines; C031234:ethylenediamine