Comparison of two techniques for sedation in dental surgery.
Forty-eight patients were randomised to receive sedation of outpatient dental surgery with midazolam. Sedation was given using the Verrill technique (24 patients) and the Glasgow Dental Hospital technique (24 patients). The differences in recovery and patient acceptability were assessed. There was no statistical difference in mean recovery times between the two groups. Memory function was examined using the Warrington memory test. Fewer patients in the Verrill group recalled the injection of local anaesthetic but they demonstrated memory defects 4 hours after sedation for words and 3 hours for faces. The Glasgow Dental Hospital group demonstrated memory defects for words up to 2 hours following sedation, but not for faces at any time. Thirty-eight patients would have dental surgery again with similar sedation. The dental surgeon found conditions for surgery inadequate in two patients. In view of the shorter duration of amnesia we recommend the Glasgow Dental Hospital technique.
Department of Anaesthesia, Western Infirmary, Glasgow.
J A
JA
Church
J S
JS
Pollock
D M
DM
Still
G D
GD
Parbrook
D000293:Adolescent; D000328:Adult; D000556:Ambulatory Surgical Procedures; D001794:Blood Pressure / Q000187:drug effects; D016292:Procedural Sedation / Q000379:methods*; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D006801:Humans; D008568:Memory / Q000187:drug effects; D008874:Midazolam / Q000008:administration & dosage*; D008875:Middle Aged; D011183:Postoperative Complications; D013997:Time Factors; D014070:Tooth / Q000601:surgery; D014081:Tooth Extraction
D008874:Midazolam