Human immunodeficiency virus infection in cells of myeloid-monocytic lineage.
We established persistent infection with a strain of human immunodeficiency virus type 1, HTLV-IIIB, in a promyelomonocytic cell line, ML-1 (CD4 antigen nearly negative and CD4 mRNA negative), and a promonocytic cell line, THP-1 (CD4 antigen positive). Different reaction of giant cell formation was found after co-cultivation of infected and uninfected cells of ML-1, HL-60, THP-1 and U-937 cell lines with uninfected and infected MOLT4 (a T-lymphoma cell line).
Ushijima
H
H
Division of AIDS Virus, National Institute of Health, Tokyo.
Dairaku
M
M
Honma
H
H
Yamaguchi
K
K
Shimizu
H
H
Tsuchie
H
H
Abe
K
K
Yamamoto
A
A
Hoshino
H
H
Müller
W E
WE
D015704:CD4 Antigens / Q000276:immunology; D002460:Cell Line; D002478:Cells, Cultured; D005434:Flow Cytometry; D005455:Fluorescent Antibody Technique; D015726:Giant Cells / Q000276:immunology / Q000382:microbiology; D006098:Granulocytes / Q000382:microbiology*; D015483:HIV Antibodies / Q000276:immunology; D015497:HIV-1 / Q000254:growth & development* / Q000276:immunology; D006801:Humans; D009000:Monocytes / Q000382:microbiology*; D014776:Virus Cultivation
D015704:CD4 Antigens; D015483:HIV Antibodies