[Renal involvement in rheumatic (systemic) diseases: new diagnostic possibilities].
Patients (pts) with rheumatoid arthritis (RA) may develop structural damage and functional deterioration of the kidney, where interstitial fibrosis and mesangioproliferative glomerulitis are seen most frequently. Compared to controls 80 pts with RA under various therapeutical regimes and 23 pts with SLE excreted immunoreactive membrane proteins of the proximal tubule at an increased rate. 30 out of 76 pts, but all with SLE, revealed a pathological pattern of proteinuria in SDS-PAGE.
Abteilung Nephrologie, Universität Frankfurt/Main.
J E
JE
Scherberich
W
W
Schoeppe
D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000150:complications*; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology*; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008297:Male; D008565:Membrane Proteins / Q000652:urine; D008875:Middle Aged; D011507:Proteinuria / Q000175:diagnosis* / Q000209:etiology
D008565:Membrane Proteins
Nierenbeteiligung bei rheumatischen (System-) Erkrankungen: neue diagnostische Möglichkeiten.