Further evidence for the importance of parental source of the Xce allele in X chromosome inactivation.
Using mice that were mosaics for both Xce and phosphoglycerate kinase (Pgk-1) alleles, we present further evidence that the parental source of the X chromosome may affect the probability of that X chromosome remaining active. The reciprocal cross differences in PGK-1 activity described here are intermediate between those published previously for other alleles of Xce.
Department of Zoology, University of Edinburgh.
D J
DJ
Fowlis
J D
JD
Ansell
H S
HS
Micklem
D000483:Alleles; D000818:Animals; D003433:Crosses, Genetic; D004303:Dosage Compensation, Genetic; D005260:Female; D008297:Male; D051379:Mice; D009030:Mosaicism; D010735:Phosphoglycerate Kinase / Q000235:genetics
D010735:Phosphoglycerate Kinase