Diazemuls versus diazepam as premedication in upper gastrointestinal endoscopy: a randomised cross-over study.
The efficacy and tolerability of Diazemuls versus conventional diazepam as endoscopic premedication was evaluated in a study with a cross-over design performed in 26 patients undergoing upper gastrointestinal tract endoscopy. No statistically significant differences were found between the two forms of premedication with regard to degree of sedation, patient compliance or recovery of psychomotor function. With respect to short-term amnesic effects, efficacy and tolerability Diazemuls was comparable to the conventional formulation of diazepam. Diazemuls may therefore be proposed as an alternative premedication for endoscopy.
Gastrointestinal Unit, L. Sacco Hospital, Milan, Italy.
G
G
Bianchi Porro
M
M
Lazzaroni
F
F
Parente
M
M
Petrillo
O
O
Sangaletti
H
H
Zhu
D000328:Adult; D000368:Aged; D003975:Diazepam / Q000008:administration & dosage*; D004381:Duodenal Ulcer / Q000473:pathology; D016099:Endoscopy, Gastrointestinal; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011292:Premedication; D011597:Psychomotor Performance / Q000187:drug effects
D003975:Diazepam