Information content of the Centre d'Etude du Polymorphisme Humain (CEPH) family structures for linkage studies.
This paper derives theoretical values for joint polymorphism information content for two markers from a family structure consisting of four grandparents, two parents, and many offspring. These data determine the efficiency of linkage map construction.
Chakravarti
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Department of Human Genetics, University of Pittsburgh, PA 15261.
D005260:Female; D005787:Gene Frequency; D008040:Genetic Linkage; D005819:Genetic Markers / Q000235:genetics; D006801:Humans; D008297:Male; D008957:Models, Genetic; D011110:Polymorphism, Genetic
D005819:Genetic Markers