Identification of seven novel protein-tyrosine kinase genes of Drosophila by the polymerase chain reaction.
We used the polymerase chain reaction to identify 7 novel tyrosine-kinase genes (dtk1 to -7) in Drosophila melanogaster, dtk4 coded for a part of the kinase catalytic domain nearly identical in sequence to that of the human receptor for insulin-like growth factor 1, whereas sequences encoded by dtk1 and dtk2 were highly homologous to that of the chicken fibroblast growth factor receptor.
Department of Biophysics and Biochemistry, Faculty of Science, University of Tokyo, Japan.
E
E
Shishido
Y
Y
Emori
K
K
Saigo
D000483:Alleles; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004247:DNA / Q000235:genetics; D003854:Deoxyribonucleotides; D004330:Drosophila / Q000201:enzymology / Q000235:genetics*; D005796:Genes; D008969:Molecular Sequence Data; D015345:Oligonucleotide Probes; D016133:Polymerase Chain Reaction / Q000379:methods; D011505:Protein-Tyrosine Kinases / Q000235:genetics*; D015183:Restriction Mapping; D012689:Sequence Homology, Nucleic Acid
D003854:Deoxyribonucleotides; D015345:Oligonucleotide Probes; D004247:DNA; D011505:Protein-Tyrosine Kinases