[New possibilities of prevention of acute gastric and intestinal ulcers in peritonitis with drugs of anti-hypoxic and antioxidant action].
A retrospective analysis has been made of 96 cases of acute erosions and peptic ulcer emerging in diffuse purulent peritonitis. The examination and treatment of 124 patients suggested that toxic peritonitis runs with excessive accumulation of lipid peroxidation products in the serum. Administration of antihypoxic drugs and antioxidants promoted stabilization of peroxidation thus preventing gastroduodenal erosions and ulcer.
Asanov
O N
ON
Khanevich
M D
MD
Shakh
B N
BN
Golubeva
L A
LA
Lapshin
V N
VN
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005561:Formates / Q000008:administration & dosage*; D006801:Humans; D000860:Hypoxia / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects* / Q000502:physiology; D008875:Middle Aged; D010437:Peptic Ulcer / Q000517:prevention & control*; D010538:Peritonitis / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism
D000975:Antioxidants; D005561:Formates; C030544:formic acid
Novye vozmozhnosti profilaktiki ostrykh iazv zheludka i kishok pri peritonite preparatami antigipoksicheskogo i antioksidantnogo riada.