Diffusion-weighted imaging of kainic acid lesions in the rat brain.
We present T2-weighted and diffusion-weighted images of kainic acid lesions in the rat brain. Our observations show improved image contrast between edematous lesions and unaffected tissue using diffusion-weighted imaging. Furthermore, we show that the anisotropic intensity changes associated with this sequence can be used to highlight white matter tracts and to provide information concerning their orientation in the rat brain.
Department of Biophysics, Hunterian Institute, Royal College of Surgeons, London.
M D
MD
King
N
N
van Bruggen
R G
RG
Ahier
J E
JE
Cremer
J V
JV
Hajnal
S R
SR
Williams
M
M
Doran
D000679:Amygdala / Q000187:drug effects / Q000473:pathology; D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000473:pathology; D003337:Corpus Callosum / Q000187:drug effects / Q000473:pathology; D003342:Corpus Striatum / Q000187:drug effects / Q000473:pathology; D004058:Diffusion; D007608:Kainic Acid / Q000009:adverse effects*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D009410:Nerve Degeneration; D011699:Putamen / Q000187:drug effects / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains
D007608:Kainic Acid