Clip electrode method for recording eye movements in experimental animals.
Both the guinea pig and squirrel monkey were used in this study. An animal model for inner ear disease was established, and each animal was subjected to vestibular function tests consisting of spontaneous nystagmus recording, positional testing, caloric testing, and optokinetic stimulation testing. Recordings of nystagmus in the guinea pig and squirrel monkey were successfully obtained by using newly devised clip electrodes. A variety of nystagmic patterns in animal models following experimentally created perilymphatic fistula and labyrinthectomy are presented in this study.
Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Japan.
Y H
YH
Young
Y
Y
Nomura
T
T
Okuno
M
M
Hara
D000818:Animals; D002150:Caloric Tests; D015834:Cochlear Diseases / Q000503:physiopathology; D004566:Electrodes; D004584:Electronystagmography / Q000295:instrumentation*; D004867:Equipment Design; D005133:Eye Movements / Q000502:physiology*; D005402:Fistula / Q000503:physiopathology; D006168:Guinea Pigs; D007759:Labyrinth Diseases / Q000503:physiopathology; D009760:Nystagmus, Physiologic / Q000502:physiology; D010498:Perilymph / Q000502:physiology; D012453:Saimiri; D014724:Vestibular Function Tests / Q000295:instrumentation*