Assignment of the fucosidase pseudogene FUCA1P to chromosome region 2q31----q32.
FUCA1P is a pseudogene of the structural fucosidase gene FUCA1. The former has been mapped to human chromosome 2, whereas the latter has been localized to chromosome 1p34----p36. We have further localized FUCA1P to chromosomal band 2q31----q32 by fluorescent in situ hybridization and digital imaging microscopy. This localization was confirmed by linkage analysis between FUCA1P and the COL3A1 gene in 2q24----q32 which gave maximal lod scores of 4.03 at 3% recombination.
Department of Medical Genetics, University of Antwerp-U.I.A., Belgium.
P
P
Coucke
K
K
Mangelschots
F
F
Speleman
P
P
Bossuyt
P
P
Van Oostveldt
B
B
Van der Auwera
B
B
Carritt
P J
PJ
Willems
D002478:Cells, Cultured; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D002889:Chromosomes, Human, Pair 2; D005796:Genes; D006801:Humans; D007621:Karyotyping; D008214:Lymphocytes / Q000201:enzymology; D011544:Pseudogenes; D005644:alpha-L-Fucosidase / Q000235:genetics*
D005644:alpha-L-Fucosidase