[Cyclosporin induced gingival hyperplasia].
Cyclosporine is a strong immunosuppressive drug, which is used specially in transplantation patients, however in some cases, like others medicines it causes, gingival overgrowth. In the present article we present five transplantations patients, (one of liver, and four of kidney), whom have taken this drug since more than a year at different dosages. One of them, never has presented overgrowth, whereas the rest cases have needed this specific periodontal treatment to solve hyperplasy. After this work, we don't find clear relationship between drug dosage-age-effect over tissues.
Gonzalez-Jaranay Ruiz
M
M
Universidad de Granada.
Mesa Aguado
F
F
D000293:Adolescent; D000328:Adult; D003524:Cyclosporins / Q000009:adverse effects*; D003777:Dental Prophylaxis; D004305:Dose-Response Relationship, Drug; D005885:Gingival Hyperplasia / Q000139:chemically induced*; D005890:Gingivectomy; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects; D016031:Liver Transplantation / Q000009:adverse effects
D003524:Cyclosporins
Hiperplasia gingival inducida por ciclosporina.