Quality of life in type 1 (insulin-dependent) diabetic patients prior to and after pancreas and kidney transplantation in relation to organ function.
Improvement of the quality of life in Type 1 (insulin-dependent) diabetic patients with severe late complications is one of the main goals of pancreas and/or kidney grafting. To assess the influences of these treatment modalities on the different aspects of the quality of life a cross-sectional study in 157 patients was conducted. They were categorized into patients pretransplant without dialysis (n = 29; Group A), pretransplant under dialysis (n = 44; Group B), posttransplant with pancreas and kidney functioning (n = 31; Group C), post-transplant with functioning kidney, but insulin therapy (n = 29; Group D), post-transplant under dialysis and insulin therapy again (n = 15; Group E) and patients after single pancreas transplantation and rejection, with good renal function, but insulin therapy (n = 9; Group F). All patients answered a mailed, self-administered questionnaire (217 questions) consisting of a broad spectrum of rehabilitation criteria. The results indicate a better quality of life in Groups C and D as compared to the other groups. In general the scores are highest in C, but without any significant difference to D. Impressive significant differences between C or D and the other groups were found especially in their satisfaction with physical capacity, leisure-time activities or the overall quality of life.(ABSTRACT TRUNCATED AT 250 WORDS)
Department of Internal Medicine Innenstadt, University of Munich, FRG.
W
W
Piehlmeier
M
M
Bullinger
J
J
Nusser
A
A
König
W D
WD
Illner
D
D
Abendroth
W
W
Land
R
R
Landgraf
D000223:Adaptation, Psychological; D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000503:physiopathology / Q000523:psychology* / Q000601:surgery*; D004644:Emotions; D004651:Employment; D005260:Female; D006801:Humans; D016030:Kidney Transplantation / Q000502:physiology / Q000523:psychology*; D008297:Male; D008960:Models, Psychological; D016035:Pancreas Transplantation / Q000502:physiology / Q000523:psychology*; D011788:Quality of Life; D012189:Retrospective Studies; D012725:Sexual Behavior; D011795:Surveys and Questionnaires