Xanthelasmoid mastocytosis.
An 8-year-old girl had small, papular vulval lesions for six years; the lesions were yellowish with numerous surface depressions. Symptoms due to the action of mastocyte mediators were observed. A biopsy specimen showed a dense monomorphous infiltrate of the deep dermis by rounded cells with granular cytoplasm and a round or oval central nucleus. The morphology of the lesions and red-purple metachromatic staining led to the diagnosis of xanthelasmoid mastocytosis. Symptoms were controlled with hydroxyzine. Annual follow-up has shown no evidence of systemic involvement to date. Surgery should be contemplated as a future therapeutic option, in view of the location of the lesions.
Servicio de Dermatologia, Hospital Clínico Universitario, Valencia, Spain.
A
A
Revert
E
E
Jordá
D
D
Ramón
J M
JM
Verdeguer
V
V
Torres
A
A
Pitarch
D002648:Child; D005260:Female; D006801:Humans; D008415:Mastocytosis / Q000473:pathology* / Q000628:therapy; D012867:Skin / Q000473:pathology; D014845:Vulvar Diseases / Q000473:pathology / Q000628:therapy