Kimura's disease and membranous nephropathy.
An interesting association of Kimura's disease and membranous nephropathy is reported in a 71-year-old Chinese patient, 40 years after emigrating to the UK from Hong Kong. Significant blood eosinophilia and a very high serum IgE level were detected, the latter with a moderate level of specificity to Candida albicans. Light microscopy of renal biopsy was unremarkable despite a proteinuria of nephrotic proportions; diffuse subepithelial dense deposits compatible with membranous nephropathy were identified on electron microscopy. The atopic nature of Kimura's disease is confirmed and C. albicans is suggested as a possible causative agent.
Akosa
A B
AB
Department of Histopathology, Wexham Park Hospital, Slough, UK.
Sherif
A
A
Maidment
C G
CG
D000368:Aged; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000150:complications* / Q000209:etiology / Q000473:pathology; D002176:Candida albicans / Q000276:immunology; D015433:Glomerulonephritis, Membranous / Q000150:complications* / Q000473:pathology; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000150:complications; D008297:Male