[Hepatitis C virus infection in different risk groups and among blood donors].
We have studied serological markers of viral hepatitis type A, B, delta and C in 7,713 blood-donors, 265 patients with a clinical diagnosis of hepatitis, 41 inmates of a mental and physical retardation institution and 41 health care workers at the same institution and 35 chronic hemodialysis patients. The results showed a 0.8% anti-HCV prevalence in blood-donors, but a higher percentage (47.5%) among HBV positive patients and in two different groups of the inmates at the mental institution (12.5% and 36%). We can not establish a relationship with the presence of anti-HCV and serological markers for HBV or H-delta V, neither with any serological markers pattern of B hepatitis nor with the anti-HCV levels and pathological findings in the biopsy of the cases in which this procedure was performed. The detection of anti-HCV has two direct applications: to exclude positive blood-donors in order to reduce the risk of post-transfusion hepatitis and to better establish a precise diagnosis in patients otherwise classified of having nonA-nonB hepatitis.
Servicio de Medicina Nuclear, Hospital de Navarra.
J L
JL
Martínez
J
J
del Hierro
A
A
Camarero
A
A
Medarde
M T
MT
López
J
J
Latasa
D000293:Adolescent; D000328:Adult; D015415:Biomarkers; D001782:Blood Donors; D002648:Child; D006282:Health Personnel; D006508:Hepatitis Antibodies / Q000032:analysis; D006511:Hepatitis B Antigens / Q000032:analysis; D006526:Hepatitis C / Q000150:complications / Q000453:epidemiology*; D006525:Hepatitis, Viral, Human / Q000150:complications / Q000453:epidemiology; D006801:Humans; D008607:Intellectual Disability / Q000150:complications; D007676:Kidney Failure, Chronic / Q000150:complications; D015995:Prevalence; D006435:Renal Dialysis; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology
D015415:Biomarkers; D006508:Hepatitis Antibodies; D006511:Hepatitis B Antigens
Estudio de la infección por virus de la hepatitis C en diferentes grupos de riesgo y en donantes de sangre.