[Evaluation of D-dimer levels in obliterating arteriopathies].
A research has been carried out for the evaluation of D-dimer serum levels by the ELISA technique at 1:200 and 1:500 dilution in 30 male patients suffering from chronic obliterating arteriopathy of the lower limbs at second and third stage of the disease and in a homogeneous control group for number, sex and age. The value difference between the two groups, for both dilutions, seems to be highly significant with higher levels in the arteriopathic patients. The extent of D-dimer levels has shown an obvious correlation in respect to the entity of the arteriopathy. It has been also observed a significant correlation between the D-dimer and LDL levels in the arteriopathic patients. The usefulness of such a parameter in order to prevent trophic lesions in the obliterating arteriopathy is emphasized for the possibility of establishing an early and prolonged thrombolytic therapy.
Clinica dermatologica, Università, Bari.
V
V
Petruzzellis
M T
MT
Ventura
T
T
Florio
T
T
Troccoli
F
F
Loconsole
N M
NM
Pellegrino
D000368:Aged; D001157:Arterial Occlusive Diseases / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis*; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D011379:Prognosis
D005338:Fibrin Fibrinogen Degradation Products; D008077:Lipoproteins, LDL
Valutazione dei tassi di D-dimero nelle arteriopatie obliteranti.