The most frequently lost allelic site in human renal cell carcinoma (D3F15S2) on the short arm of chromosome 3 has homologous sequences on rat chromosome 8.
It has previously been shown that human chromosome 3 has banding homology to rat chromosome 8. We have previously isolated a cDNA from the D3F15S2 region and designated the gene as RIK. In the present study, we localized the homolog of this gene to rat chromosome 8.
Department of Tumor Biology, Karolinska Institutet, Stockholm, Sweden.
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Erlandsson
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Szpirer
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Islam
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Boldog
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Klein
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Ingvarsson
D000483:Alleles; D000818:Animals; D002292:Carcinoma, Renal Cell / Q000235:genetics*; D002460:Cell Line; D002871:Chromosome Banding; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D002893:Chromosomes, Human, Pair 3; D015342:DNA Probes; D006801:Humans; D006822:Hybrid Cells / Q000166:cytology; D007680:Kidney Neoplasms / Q000235:genetics*; D051379:Mice; D051381:Rats; D011919:Rats, Inbred Strains / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid
D015342:DNA Probes