[Post-ischemia normal function of living related kidney transplants after preservation with HTK solution].
This study reports on the first clinical use of HTK preservation solution devised by Bretschneider in renal transplantation. Using this HTK solution, nine living related donor kidneys subjected to cold ischemia for up to 4 h were consecutively transplanted between 1987 and 1989. The postoperative function of the donor and recipient kidneys is analyzed. The endogenous creatinine clearance and the plasma creatinine level are used as function parameters. Within 24-48 h after transplantation a postischemic normal graft function occurred. With triple drug therapy the transplanted kidneys showed an increase in renal function identical with that in the donor's single remaining kidney. Within 7 postoperative days no perfusion damage and no HTK or CyA nephrotoxicity was observed.
Chirurgische Klinik und Poliklinik, Technischen Universität München, Klinikum rechts der Isar.
J
J
Vieweg
C D
CD
Heidecke
T
T
Beckurts
M
M
Hölscher
D000328:Adult; D000368:Aged; D003404:Creatinine / Q000097:blood; D005260:Female; D005947:Glucose; D006801:Humans; D007668:Kidney / Q000503:physiopathology; D007677:Kidney Function Tests; D016030:Kidney Transplantation / Q000502:physiology*; D008297:Male; D008353:Mannitol; D008875:Middle Aged; D009926:Organ Preservation / Q000379:methods*; D011183:Postoperative Complications / Q000503:physiopathology; D011189:Potassium Chloride; D011343:Procaine
C039984:Bretschneider cardioplegic solution; D008353:Mannitol; D011343:Procaine; D011189:Potassium Chloride; D003404:Creatinine; D005947:Glucose
Postischämische Normalfunktion von Verwandtennierentransplantaten nach Protektion mit HTK-Lösung.