[The morphological characteristics of sarcoma M1 cells before and after irradiation].
Morphology of the death of rat sarcoma M1, cells before and in varying time after irradiation at doses of 10 and 20 Gy with and without metronidazole (as a radiosensitizer) was investigated at the light optic and electron microscopic levels. Two types of death: necrosis and apoptosis with the prevalence of the former were revealed. Irradiation and the use of metronidazole did not influence the type of death of sarcoma M1 cells.
Abrosimov
A Iu
AIu
Skoropad
V Iu
VIu
D000818:Animals; D016923:Cell Death / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D008795:Metronidazole / Q000627:therapeutic use; D008854:Microscopy, Electron; D009336:Necrosis; D009368:Neoplasm Transplantation; D011836:Radiation Tolerance; D011879:Radiotherapy Dosage; D051381:Rats; D012513:Sarcoma, Experimental / Q000532:radiotherapy / Q000648:ultrastructure*
D008795:Metronidazole
Morfologicheskaia kharakteristika kletok sarkomy M1 do i posle oblucheniia.