A complete solution to the model describing Carr-Purcell and Carr-Purcell-Meiboom-Gill experiments in a two-site exchange system.
A general solution for the relaxation decay function observed in both CP and CPMG spin-echo experiments, performed on systems governed by a two-site chemical exchange mechanism, is presented. This solution not only provides the relaxation time constants, but also supplies complete information about relative component sizes. Solutions are analytical, but results are complex enough to warrant computer-assisted calculations. Programming suggestions, based on the extensive tests performed, are provided.
Radiology Department, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina 27103.
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D000465:Algorithms; D003198:Computer Simulation; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D012984:Software