Central nervous system involvement by cutaneous T cell lymphoma.
Central nervous system disease in cutaneous T cell lymphoma is uncommon and is usually not considered in standard therapeutic regimens. We report three patients who had cutaneous T cell lymphoma with involvement of the central nervous system and review the cases of 28 such patients reported in the literature. Potential risk factors, the reliability of various diagnostic tests, and potential therapeutic modalities are discussed.
Grevelink
S A
SA
Department of Medicine, Duke University Medical Center, Durham, NC 27710.
Fuller
G N
GN
Olsen
E A
EA
D000368:Aged; D016543:Central Nervous System Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary*; D005260:Female; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000473:pathology*