Identification of seven novel protein-tyrosine kinase genes of Drosophila by the polymerase chain reaction.
We used the polymerase chain reaction to identify 7 novel tyrosine-kinase genes (dtk1 to -7) in Drosophila melanogaster, dtk4 coded for a part of the kinase catalytic domain nearly identical in sequence to that of the human receptor for insulin-like growth factor 1, whereas sequences encoded by dtk1 and dtk2 were highly homologous to that of the chicken fibroblast growth factor receptor.
Shishido
E
E
Department of Biophysics and Biochemistry, Faculty of Science, University of Tokyo, Japan.
Emori
Y
Y
Saigo
K
K
D000483:Alleles; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004247:DNA / Q000235:genetics; D003854:Deoxyribonucleotides; D004330:Drosophila / Q000201:enzymology / Q000235:genetics*; D005796:Genes; D008969:Molecular Sequence Data; D015345:Oligonucleotide Probes; D016133:Polymerase Chain Reaction / Q000379:methods; D011505:Protein-Tyrosine Kinases / Q000235:genetics*; D015183:Restriction Mapping; D012689:Sequence Homology, Nucleic Acid
D003854:Deoxyribonucleotides; D015345:Oligonucleotide Probes; D004247:DNA; D011505:Protein-Tyrosine Kinases