[Auricular chondritis, malignant glomerulonephritis and pulmonary hemorrhage].
Relapsing polychondritis is a rare connective tissue disorder characterized by inflammation of cartilagenous structures such as ears, nose, joints, trachea and larynx. Renal disease is unusual. A 41 years old man presented with auricular chondritis, subacute renal failure and lung hemorrhage. A renal biopsy disclosed a diffuse proliferative glomerulonephritis with extensive crescents. Immunofluorescent studies suggested a GNRP type III so called "non immunologic disease". He was treated by prednisone and plasmapheresis with rapid disappearance of pulmonary hemorrhages and good renal functional improvement.
Dracon
M
M
Clinique Néphrologique, Hôpital Calmette, Lille.
Noël
C
C
Ramon
P
P
Wallaert
B
B
Tonnel
A B
AB
Gosselin
B
B
Lelièvre
G
G
Tacquet
A
A
D000328:Adult; D005921:Glomerulonephritis / Q000150:complications* / Q000473:pathology; D006470:Hemorrhage / Q000150:complications*; D006801:Humans; D008171:Lung Diseases / Q000150:complications*; D008297:Male; D010956:Plasmapheresis; D011081:Polychondritis, Relapsing / Q000150:complications* / Q000628:therapy; D011241:Prednisone / Q000627:therapeutic use
D011241:Prednisone
Chondrite auriculaire, glomérulonéphrite maligne et hémorragies pulmonaires.