Ultrastructural studies on the effects of hypergravity environment on the parathyroid glands in golden hamsters of different ages.
The ultrastructure of the parathyroid glands of infantile, young, adult and senile golden hamsters subjected to a hypergravity environment was studied. In the parathyroid glands of 5-, 10- and 20-day-old, and 1- and 3-month-old golden hamsters exposed to a hypergravity environment, the Golgi complexes were significantly increased, and in 5-, 10- and 20-day-old, and 1- and 8-month-old animals exposed to a hypergravity environment, the cisternae of the granular endoplasmic reticulum appeared to be increased as compared to those of each control group. In addition, in centrifuged animals numerous prosecretory granules were observed in the Golgi areas, and many secretory granules were located in the peripheral cytoplasm. The ultrastructure of the parathyroid glands of 14-month-old centrifuged animals resembled that of 14-month-old control animals. These results suggest that the secretory activity of the parathyroid gland may be stimulated in infantile, young and adult golden hamsters subjected to a hypergravity environment and may not be stimulated in senile animals subjected to a hypergravity environment.
Shoumura
S
S
Department of Anatomy, Gifu University School of Medicine, Japan.
Emura
S
S
Utsumi
M
M
Chen
H
H
Yamahira
T
T
Hayakawa
D
D
Arakawa
M
M
Isono
H
H
D000375:Aging; D000818:Animals; D006224:Cricetinae; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D006056:Golgi Apparatus / Q000648:ultrastructure; D006112:Gravitation; D008247:Lysosomes / Q000648:ultrastructure; D008647:Mesocricetus / Q000033:anatomy & histology*; D008854:Microscopy, Electron; D010280:Parathyroid Glands / Q000254:growth & development / Q000502:physiology / Q000648:ultrastructure*; D012016:Reference Values; D014617:Vacuoles / Q000648:ultrastructure