Identification of disease genes: recent successes.
As we continue to localize, sequence, and characterize more and more genes and as we increase our understanding of the biologic function of the gene products--and the nature of the disruptions that mutations can cause--we will come closer to the goals of diagnosis, prevention, and therapy. Progress in the field is proceeding at a pace that no one could have envisioned a decade ago.
Collins
F S
FS
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor.
D002874:Chromosome Mapping; D002877:Chromosomes, Human; D030342:Genetic Diseases, Inborn / Q000235:genetics*; D006801:Humans; D009154:Mutation