The effect of dermatophyte species and density of infection on the pathology of ringworm.
In this study we have measured the mean hyphal length as a function of the density of infection in skin surface biopsies from patients suffering from infection with different species of dermatophyte. The tissue response in the epidermis and dermis of these patients was evaluated for the degree of eczematization (epidermal thickening, spongiosis and dermal infiltrate) in periodic acid Schiff stained histological sections, employing visual analogue scales. There was no correlation between mean hyphal density and the degree of eczematization.
Department of Dermatology, University of Wales College of Medicine, Heath Park, Cardiff, UK.
A J
AJ
Samdani
P J
PJ
Dykes
R
R
Marks
D000328:Adult; D001707:Biopsy, Needle; D004817:Epidermis / Q000473:pathology*; D004821:Epidermophyton / Q000302:isolation & purification* / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000382:microbiology / Q000473:pathology*; D014005:Tinea / Q000382:microbiology* / Q000473:pathology; D014249:Trichophyton / Q000302:isolation & purification* / Q000502:physiology