[The behavior of serum hCG level in normal and disordered pregnancy--a prognostic factor].
The increase of serum hCG was determined in 305 pregnant women at least twice in the first 10 to 12 weeks of pregnancy. In a large number of cases this was done to rule out a disturbance of pregnancy. The results were evaluated by means of a comparison to the time-dependent changes of the normal range. They were classified in the following manner: 1 = Normally increasing values, 2 = Values lower than normal, but normal increase, 3 = values to low and increasing too slowly, 4 = Serum hCG too low or declining, 5 = initially normal values failing to rise. A type 4 secretion pattern was invariably followed by a demise of pregnancy. In about one half of the cases showing a type 2 pattern, the pregnancy either miscarried or was found to be in an ectopic location. In normal pregnancies, type 2 pattern was found in 29% and type 1 in 71%. A comparison of the results of the first and second hCG determination revealed close agreement in more than 90% of the cases, and in 84% when the comparison was extended to a third sample.
Arsenow
H
H
Abteilung für gynäkologische Endokrinologie, Johann-Wolfgang-Goethe-Universität zu Frankfurt am Main.
Dericks-Tan
J S
JS
Taubert
H D
HD
D000022:Abortion, Spontaneous / Q000097:blood / Q000175:diagnosis; D000328:Adult; D006063:Chorionic Gonadotropin / Q000097:blood*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood* / Q000175:diagnosis*; D011261:Pregnancy Trimester, First; D011271:Pregnancy, Ectopic / Q000097:blood / Q000175:diagnosis; D012016:Reference Values
D006063:Chorionic Gonadotropin
Das Verhalten des Serum-hCG-Spiegels bei normalen und gestörten Schwangerschaften--ein prognostischer Faktor.