[30 years experience with haloperidol].
Haloperidol, a butyrophenone derivative, was first used 30 years ago and has since become one the most frequently prescribed neuroleptics, employed in the treatment of numerous psychiatric and neurological syndromes. It has a very good antipsychotic effect; its sedative effects are moderate compared against weakly potent neuroleptics, and its vegetative side effects are only slight. In a review of the literature, the data found during the past 30 years are commented upon, such as data on pharmacodynamics, pharmacokinetics, indications, undesirable effects, interactions, dosage, contraindications and precautionary measures - all of them having implications on research on neuroleptics as a whole.
Bandelow
B
B
Psychiatrische Universitätsklinik Göttingen.
Müller
P
P
Rüther
E
E
D001921:Brain / Q000187:drug effects; D018492:Dopamine Antagonists; D004409:Dyskinesia, Drug-Induced / Q000097:blood / Q000209:etiology*; D006220:Haloperidol / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006801:Humans; D011618:Psychotic Disorders / Q000097:blood / Q000188:drug therapy* / Q000523:psychology
D018492:Dopamine Antagonists; D006220:Haloperidol
30 Jahre Erfahrung mit Haloperidol.