Cardiac angiosarcoma: a case report.
Primary neoplasms of the heart are rare and difficult to diagnose prior to surgery, even with modern imaging techniques. Often, the tumors are diagnosed only at autopsy. Angiosarcoma is the most common malignant neoplasm. This disease is most commonly found in middle-aged men, and the tumor is most often located in the right atrium. It commonly causes blood flow abnormalities, extensively infiltrates cardiac structures, and may extend through the heart wall to involve adjacent structures. Metastatic spread at the time of diagnosis is common, and surgical mortality is high. We present a case of primary angiosarcoma involving the right ventricle of the heart. This tumor developed 6 months after the patient had undergone coronary artery bypass surgery. The patient was initially thought to have a massive thrombus within the right ventricle but at surgery was found to have a malignant neoplasm invading the myocardium. Subsequently, he was found to have pulmonary metastases. A debulking procedure was performed, and the patient was started on chemotherapy. Rather prompt improvement occurred after the debulking procedure, but subsequent studies have indicated progression of the pulmonary metastases despite ongoing chemotherapy.
Brown
B C
BC
Pathology Department, Piedmont Hospital, Atlanta, GA 30309.
Mason
T E
TE
Ballard
W P
WP
Wickliffe
C W
CW
Bone
D
D
D000328:Adult; D006338:Heart Neoplasms / Q000175:diagnosis / Q000628:therapy; D006394:Hemangiosarcoma / Q000175:diagnosis / Q000556:secondary / Q000628:therapy; D006801:Humans; D008297:Male