Antituberculosis agents. V: Alpha-[5-(5-nitro-2-furyl)-1,3,4-oxadiazol-2-ylthio]acethydrazide and related compounds.
alpha-[5-(5-Nitro-2-furyl)-1,3,4-oxadiazol-2-ylthio]aceth ydrazide, alpha-[5-(5-nitro-2-furyl)-1,3,4-oxadiazol-2-ylthio]acetamid e, delta-allyl-1-[( 5-(5-nitro-2-furyl)-1,3,4-oxadiazol-2-ylthio]acety) thiosemicarbazide, and other related compounds have been synthesised for testing against Mycobacterium tuberculosis.
Natural Drugs Division, PCSIR Laboratories, Peshawar, Pakistan.
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Mir
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Siddiqui
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Comrie
D000995:Antitubercular Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D005663:Furans / Q000138:chemical synthesis / Q000494:pharmacology; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D010069:Oxadiazoles / Q000138:chemical synthesis*; D013329:Structure-Activity Relationship
D000995:Antitubercular Agents; D005663:Furans; D010069:Oxadiazoles; C070885:(5-(nitro-2-furyl)-1,3,4-oxadiazol-2-ylthio)acethydrazide