Conservative management of cervical intraepithelial neoplasia during pregnancy.
Conservative treatment of a pregnant woman with moderate dysplasia that progressed to microinvasive carcinoma within 6 months is presented along with a review of the relevant literature to date. Pregnancy does not necessarily create special difficulties for the detection and diagnosis of cervical lesions as long as the patient is followed carefully. In this case, close observation using cytology and colposcopy along with colposcopically directed excisional biopsy postponed the need for more aggressive intervention, while minimizing possible disruption of the pregnancy and danger to the mother and infant. A simple hysterectomy performed 6 weeks postpartum proved successful and the cancer has not recurred.
Hospital of the University of Pennsylvania, Philadelphia 19104.
R
R
Giuntoli
I T
IT
Yeh
N
N
Bhuett
W
W
Chu
K
K
Van Leewen
P
P
Van der Lans
D000328:Adult; D001706:Biopsy; D002278:Carcinoma in Situ / Q000473:pathology; D002585:Cesarean Section; D005260:Female; D006801:Humans; D007044:Hysterectomy; D009361:Neoplasm Invasiveness; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery