Protection tests in pigs vaccinated with the lapinized Chinese strain of hog cholera virus (HCV) previously adapted in a minipig kidney (MPK) cell line, to challenge infection with virulent HCV.
Pigs which had been vaccinated with the Lapinized Chinese strain of Hog Cholera Virus previously adapted in a minipig cell line cultures (MPK-LC-HCV), resultet to be protected when they were subjected to challenge infection with virulent Hog Cholera Virus (HCV) 6 or 11 months later. The challenge virus was never isolated from any of the vaccinated pigs. The MPK-LC-HCV vaccine induced a significant rise of the antibody titer to the HCV in pigs kept under field conditions.
Scuola per la Ricerca Scientifica, Fondazione Iniziative Zooprofilattiche e Zootecniche, Brescia, Italy.
G L
GL
Gualandi
M
M
Ferrari
G
G
Cardeti
M
M
Boldini
C
C
Buonavoglia
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002460:Cell Line; D006691:Classical Swine Fever / Q000517:prevention & control*; D006692:Classical Swine Fever Virus / Q000276:immunology* / Q000472:pathogenicity; D009500:Neutralization Tests; D013552:Swine; D013556:Swine, Miniature; D014611:Vaccination / Q000662:veterinary*; D014765:Viral Vaccines; D014774:Virulence
D000914:Antibodies, Viral; D014765:Viral Vaccines