Central pulverulent (Coppock) cataracts. A sibship of two Arab females with full-cousin normal parents.
Two Arab (Saudi) sisters are described each with bilateral typical central pulverulent (powdery) or Coppock cataracts. As their unaffected parents are first cousins, the heredity is probably autosomal recessive, unlike the autosomal dominant heredity of the vast majority of previously described cases in the literature. Chromosomes were normal in all four individuals. There are no other children in the family. Both children and both parents were phenotypically Fy a - b+, reasonably common in Arab populations, so that any linkage to the Duffy blood group is neither supported nor refuted.
Hegab
S
S
Eye Department, Ibn Sina Hospital, Kuwait.
Sheriff
S M
SM
al-Awadi
S
S
Naguib
K K
KK
Teebi
A
A
Phillips
C I
CI
D002386:Cataract / Q000208:ethnology / Q000235:genetics*; D002675:Child, Preschool; D003241:Consanguinity; D004375:Duffy Blood-Group System / Q000235:genetics; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D010375:Pedigree; D012529:Saudi Arabia / Q000208:ethnology
D004375:Duffy Blood-Group System