[Hemorheology in clinical practice. Introduction to the notion of hemorheologic profile].
Although the non-Newtonian characteristics of blood have now been accurately defined, the influence and effect of a hyperviscosity syndrome at the onset of ischemia and in oxygen transport to the tissues remains within the realm of assumptions. Using a simple theoretical approach it can be shown that oxygen transport capacity to the tissues is proportional to the radio H/eta s (where H = hematocrit, eta s = blood viscosity), as long as vascular bed geometry remains constant (with no sign of compensatory vasodilation). With the help of examples, the authors show the changes in oxygen transport as a function of various rheological parameters (red cell aggregation ans deformability). Further, the authors introduce the concept of a hemorheological profile for taking all the hemorheological parameters into consideration and for standardising the presentation of the results for hyperviscosity syndromes.
U 284 INSERM, Vandoeuvre Les Nancy.
J F
JF
Stoltz
M
M
Donner
S
S
Muller
A
A
Larcan
D001809:Blood Viscosity; D002318:Cardiovascular Diseases / Q000097:blood*; D006801:Humans; D010100:Oxygen / Q000378:metabolism; D012212:Rheology
D010100:Oxygen
L'hémorhéologie en pratique clinique. Introduction à la notion de profil hémorhéologique.