Laser ablation ability of different fiber tips on human arteries. The role of photothermal effect.
To compare laser ablation abilities of bare tip and metal probe as well as spectraprobe, specimens from human normal and atherosclerotic aorta were irradiated with Nd-YAG laser. To evaluate the influence of photothermal effect thermal energy productions of 3 tips were measured with a calorimeter. The results showed that the bare tip produced the most effective ablation in arterial atheroma, followed by the metal probe and the spectraprobe. Similarly, the ratio of the ablation area on atheroma to that on normal vessel was the best with the bare tip and the worst with the spectraprobe. However, the extent of surrounding tissue damage adjacent to the ablation crater was the largest with the bare tip and the smallest with the spectraprobe. These differences cannot be explained only by variations in the photothermal effect, since thermal energy production is proved to be almost equal among the 3 laser fiber tips.
Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing.
X M
XM
Yang
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H
Manninen
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S
Soimakallio
D000368:Aged; D000369:Aged, 80 and over; D016342:Angioplasty, Laser / Q000009:adverse effects / Q000295:instrumentation; D001161:Arteriosclerosis / Q000473:pathology / Q000601:surgery*; D006358:Hot Temperature; D006801:Humans; D066298:In Vitro Techniques; D008297:Male