[The effect of metacin on the activity of digestive enzymes participating in the hydrolysis of fats normally and in stress].
The effect of a peripheral cholinolytic methacin on the activity of lipolytic enzymes of the pancreas and small intestine was studied on intact and stress-exposed animals. The drug was shown to induce certain changes in the activity of lipolytic enzymes. The preliminary administration of methacin attenuates the shifts in the activity of the studied enzymes observed under stress action.
Zakirov
U B
UB
Makhsumov
Sh M
ShM
Teshabaev
D Ia
DIa
D000818:Animals; D004041:Dietary Fats / Q000378:metabolism*; D004063:Digestion / Q000187:drug effects* / Q000502:physiology; D004353:Drug Evaluation, Preclinical; D005260:Female; D006868:Hydrolysis; D008049:Lipase / Q000037:antagonists & inhibitors; D008297:Male; D008994:Monoacylglycerol Lipases / Q000037:antagonists & inhibitors; D010115:Oxyphenonium / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000188:drug therapy* / Q000201:enzymology / Q000209:etiology; D013696:Temperature; D013997:Time Factors
D004041:Dietary Fats; D010115:Oxyphenonium; D008994:Monoacylglycerol Lipases; D008049:Lipase
Vliianie metatsina na aktivnost' pishchevaritel'nykh fermentov, uchastvuiushchikh v gidrolize zhirov, v norme i pri stresse.