[Essential hypertension. Treatment with nifedipine and levels of insulin, glucagon, gastrin and prolactin].
In 40 patients (pts) with essential hypertension (EH) the plasma levels of insulin, glucagon, gastrin and prolactin during 2 week therapy with nifedipine were evaluated. In pts with EH there were higher levels of hormones than in control subjects. During nifedipine therapy there was no elevation of the plasma hormone levels although the blood pressure was lowered. This study shows that there are other than hypertension factors in the pathogenesis of elevated hormone levels in EH.
Katedra i Klinika Nefrologii Slaskiej Akademii Medycznej.
R
R
Wnuk
F
F
Kokot
D000328:Adult; D005260:Female; D005755:Gastrins / Q000097:blood; D005934:Glucagon / Q000097:blood; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000188:drug therapy*; D007328:Insulin / Q000097:blood; D008297:Male; D008875:Middle Aged; D009543:Nifedipine / Q000627:therapeutic use*; D011388:Prolactin / Q000097:blood
D005755:Gastrins; D007328:Insulin; D011388:Prolactin; D005934:Glucagon; D009543:Nifedipine
Nadciśnienie tetnicze samoistne. Leczenie nifedypina a poziom insuliny, glukagonu, gastryny i prolaktyny.