An in vivo chloroquine sensitivity study in relation to low transmission potential and imported malaria in Kerala.
The study highlights the presence of chloroquine resistant Plasmodium falciparum strains in Kerala state, India for the first time. The emergence of chloroquine resistant P. falciparum in a low transmission area is dependent on the imported cases while build up of resistance is mainly due to persistence of resistant parasites which have more opportunities for transmission.
Nagaraj
C
C
National Malaria Eradication Programme, Delhi.
Sugathan
N
N
Chakrabarti
N K
NK
Narasimham
M V
MV
D000818:Animals; D002738:Chloroquine / Q000627:therapeutic use*; D003132:Commerce; D004351:Drug Resistance; D006801:Humans; D007194:India / Q000453:epidemiology; D016778:Malaria, Falciparum / Q000188:drug therapy / Q000453:epidemiology* / Q000635:transmission; D010963:Plasmodium falciparum / Q000187:drug effects*
D002738:Chloroquine