[Immunoregulating phenomena in patients with alcoholic cirrhosis].
Several immunologic changes, both humoral and cellular, have been described in patients with post-alcoholic cirrhosis. One of these changes was a polyclonal hypergammaglobulinemia which can be produced by a failure in the immunoregulation dynamics. The number of leukocytes, as well as lymphocytic population and subpopulation, did not prove significant differences between healthy people and patients. The seric immunoglobulin showed an increase of IgG in cirrhotics. The synthesis of immunoglobulins "in vitro" showed increased productions in cirrhotics; this being spontaneous in IgA and induced by pokeweed in the case of IgG and IgA.
Esparza Echevarría
B
B
Universidad del País Vasco/Euskal Herriko Unibertsitatea, Facultad de Medicina, Departamento de Medicina, Lejona, Vizcaya.
de las Heras Niño
B
B
Solano López
D
D
Martínez Odriozola
P
P
de la Villa
F M
FM
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000276:immunology*; D007070:Immunoglobulin A / Q000378:metabolism; D007074:Immunoglobulin G / Q000378:metabolism; D007075:Immunoglobulin M / Q000378:metabolism; D007958:Leukocyte Count; D008104:Liver Cirrhosis, Alcoholic / Q000276:immunology*; D016131:Lymphocyte Subsets; D008297:Male; D008875:Middle Aged
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M
Estudio de los fenómenos inmunorregulatorios en pacientes con cirrosis alcohólica.