Histological study of furcation perforations treated with tricalcium phosphate, hydroxylapatite, amalgam, and Life.
One-hundred twenty experimental furcation perforations were created in the mandibular and maxillary premolars and molars of six rhesus monkeys. Tricalcium phosphate, hydroxylapatite, amalgam, and Life were used to repair the furcation perforations. The animals were sacrificed at the intervals of 2, 4, and 6 months after the experiment. Histological evaluation revealed lack of complete healing of furcation perforations repaired with any materials. Epithelium was present in the furcation perforations in both experimental and positive control groups. No hard tissue formation was observed in this study. Inflammation in the furcation area may be due to inadequate sealing ability of the repair materials.
Department of Endodontics, University of Medicine and Dentistry, New Jersey Dental School, Newark.
R
R
Balla
C J
CJ
LoMonaco
J
J
Skribner
L M
LM
Lin
D000818:Animals; D001424:Bacterial Infections; D001672:Biocompatible Materials; D002126:Calcium Hydroxide / Q000627:therapeutic use / Q000633:toxicity; D002130:Calcium Phosphates / Q000627:therapeutic use / Q000633:toxicity; D003723:Dental Amalgam / Q000627:therapeutic use / Q000633:toxicity; D003764:Dental Materials / Q000627:therapeutic use / Q000633:toxicity; D005260:Female; D006882:Hydroxyapatites / Q000627:therapeutic use / Q000633:toxicity; D008253:Macaca mulatta; D008297:Male; D012387:Root Canal Filling Materials; D014092:Tooth Root / Q000293:injuries*; D014945:Wound Healing
D001672:Biocompatible Materials; D002130:Calcium Phosphates; D003764:Dental Materials; D006882:Hydroxyapatites; D012387:Root Canal Filling Materials; C485817:beta-tricalcium phosphate; D003723:Dental Amalgam; C040408:Life (dental material); C018392:tricalcium phosphate; D002126:Calcium Hydroxide