Comparative analysis of autosomes in karyotypes from pig and rabbit using RBG-banding and in situ hybridization.
The chromosomal location of the porcine gene for glucose phosphate isomerase (GPI) was previously mapped to 6p 12----6q21 in the pig karyotype. The replication patterns and morphology of this chromosome are very similar to those of chromosome 14 in the rabbit karyotype. With combined in situ hybridization and RBG-band induction it was demonstrated that the porcine GPI-probe hybridized most frequently to 14p11----14q12 in the rabbit karyotype, indicating a close relationship between morphology, replication pattern and gene location.
Department of Anatomy and Cytology, Odense University, Denmark.
B S
BS
Poulsen
K
K
Kristiansen
M
M
Rønne
D000818:Animals; D002871:Chromosome Banding; D002874:Chromosome Mapping; D005260:Female; D005956:Glucose-6-Phosphate Isomerase / Q000235:genetics; D007621:Karyotyping; D008297:Male; D009693:Nucleic Acid Hybridization; D011817:Rabbits / Q000235:genetics*; D013045:Species Specificity; D013552:Swine / Q000235:genetics*
D005956:Glucose-6-Phosphate Isomerase