[Studies of morphometric analysis and cell cycle of gastric epithelia of rat administered minimal mixed bile acids].
The gastric epithelia of the rat after administrated with the minimal mixed bile acids and lysozyme for 9-weeks were studied using morphometric analysis and anti-Bromodeoxyuridine staining immunohistochemistry. Our results show that the atrophic changes and increased anti-BrdU antibody staining positive and mitotic cells of the pyloric glands area in the group administration only bile acids. Lysozyme inhibited bile acids activation on these changes of this area.
Department of Veterinary Surgery, Yamaguchi University.
T
T
Murata
R
R
Wada
H
H
Abe
N
N
Kuwabara
Y
Y
Fukuda
D000818:Animals; D001647:Bile Acids and Salts / Q000494:pharmacology*; D001973:Bromodeoxyuridine / Q000378:metabolism; D002453:Cell Cycle; D004848:Epithelium / Q000187:drug effects / Q000473:pathology; D005748:Gastric Fundus / Q000473:pathology; D005753:Gastric Mucosa / Q000187:drug effects / Q000473:pathology*; D006651:Histocytochemistry; D008297:Male; D011708:Pylorus / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains
D001647:Bile Acids and Salts; D001973:Bromodeoxyuridine