[Respiratory distress and multiple organ failure after intravesical instillation of BCG].
A case of probable hypersensitivity reaction with multi-organic failure, following bladder installation of BCG, in a male with a diagnosis of bladder carcinoma is presented. The patient developed respiratory, renal and liver failure as well as leukocytosis, thrombopenia and an increase in muscular enzymes. It was resolved with hemodynamic support. The rare complication, occasionally described in medical literature and its probable pathogenic mechanisms are discussed.
Sección de Neumolgía, Hospital de la Vila Joiosa-Benidorm, Alicante.
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Chiner
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Larramendi
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Carbonell
J L
JL
Calpe
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L
Rosado
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A
Vilar
D000283:Administration, Intravesical; D001500:BCG Vaccine / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000209:etiology*; D012131:Respiratory Insufficiency / Q000209:etiology*; D001749:Urinary Bladder Neoplasms / Q000628:therapy
D001500:BCG Vaccine
Distress respiratorio y fracaso multiorgánico tras instilación intravesical de BCG.