[Acute renal failure due to endocapillary proliferative glomerulonephritis in a patient with IBL-like T-cell lymphoma].
A 72-year-old man was admitted of generalized lymphadenopathy and oliguria on December 12, 1987. Laboratory findings revealed progressive renal impairment, polyclonal hypergammaglobulinemia, and reduction of serum complements. A cervical lymph node was typically suitable for histology of IBL-like T-cell lymphoma. The surface markers of lymph node were mainly CD2 (+) and CD3 (+) and clonal proliferation of lymphoma cells was proved by TCR-beta gene rearrangement. Renal biopsy to examine the pathogenesis of acute renal failure revealed endocapillary proliferative glomerulonephritis without invasion of lymphoma cells. Both lymphadenopathy and renal failure were improved by successful administration of prednisolone and hemodialysis. Although relapsed tumor was partially responded to vincristine and prednisolone, he died of alimentary tract bleeding. We reported a case of IBL-like T-cell lymphoma with acute renal failure due to endocapillary proliferative glomerulonephritis.
Department of Internal Medicine, Aoto Hospital, School of Medicine Jikei University.
Y
Y
Yamazaki
S
S
Inaba
T
T
Nemoto
K
K
Iizuka
T
T
Fujikawa
J
J
Horiguchi
H
H
Yamada
D058186:Acute Kidney Injury / Q000209:etiology*; D000368:Aged; D001706:Biopsy; D015432:Glomerulonephritis, Membranoproliferative / Q000150:complications*; D006801:Humans; D007119:Immunoblastic Lymphadenopathy / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology; D016399:Lymphoma, T-Cell / Q000150:complications* / Q000473:pathology; D008297:Male