Use of non-collagen markers in osteoporosis studies.
Clinical and research laboratories routinely measure various hormonal and nonhormonal parameters of calcium and phosphorus metabolism, and markers of bone turnover. Such measurements may help clinical decision-making relating to metabolic bone disease and osteoporosis. Molecular biological and cell-culture techniques are being used in basic biochemical research on bone-cell metabolism. Results may aid understanding of normal and abnormal regulation of the bone-cell metabolism, and thus provide further insights relating to the diagnosis and prevention of osteoporosis.
Department of Clinical Chemistry, University of Kuopio, Finland.
M T
MT
Parviainen
A
A
Pirskanen
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A
Mahonen
E M
EM
Alhava
P H
PH
Mäenpää
D015055:1-Carboxyglutamic Acid / Q000652:urine; D000328:Adult; D000368:Aged; D000469:Alkaline Phosphatase / Q000378:metabolism; D015415:Biomarkers; D002117:Calcitriol / Q000378:metabolism; D003094:Collagen / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010006:Osteoblasts / Q000378:metabolism; D015675:Osteocalcin / Q000097:blood; D010024:Osteoporosis / Q000378:metabolism*; D012516:Osteosarcoma / Q000378:metabolism
D015415:Biomarkers; D015675:Osteocalcin; D015055:1-Carboxyglutamic Acid; D003094:Collagen; D000469:Alkaline Phosphatase; D002117:Calcitriol