CT scan abnormalities and outcome of chronic schizophrenia.
The authors evaluated the relationship between brain morphological characteristics assessed by means of computerized tomography and the 2-year clinical and social outcomes of 18 patients with chronic schizophrenia. Cerebral structural abnormalities, especially cortical atrophy, were associated with a poorer outcome in several areas of clinical and social functioning.
Vita
A
A
Schizophrenia Research Center, University of Milan, Italy.
Dieci
M
M
Giobbio
G M
GM
Azzone
P
P
Garbarini
M
M
Sacchetti
E
E
Cesana
B M
BM
Cazzullo
C L
CL
D000328:Adult; D001284:Atrophy / Q000473:pathology; D001921:Brain / Q000033:anatomy & histology* / Q000000981:diagnostic imaging / Q000473:pathology; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012559:Schizophrenia / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D012720:Severity of Illness Index; D012917:Social Adjustment; D014057:Tomography, X-Ray Computed