A novel hepatoprotective gamma-lactone, MH-031. I. Discovery, isolation, physico-chemical properties and structural elucidation.
Research Center, Taisho Pharmaceutical Co., Ltd., Saitama, Japan.
Y
Y
Itoh
H
H
Shimura
M
M
Ito
N
N
Watanabe
M
M
Yamagishi
M
M
Tamai
K
K
Hanada
D015107:4-Butyrolactone / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D002478:Cells, Cultured; D005688:Galactosamine / Q000037:antagonists & inhibitors / Q000633:toxicity; D007783:Lactones / Q000302:isolation & purification* / Q000494:pharmacology; D008099:Liver / Q000187:drug effects; D051381:Rats; D013302:Streptomyces / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D007783:Lactones; C071013:3-(2-oxo-2,5-dihydro-3-furanyl)propanoic acid; D005688:Galactosamine; D015107:4-Butyrolactone