[Nutritional regulation of serum osteocalcin: study in kwashiorkor].
The serum levels of osteocalcin (bone gla protein) in two groups of Senegalese children, healthy controls and severely malnourished (kwashiorkor) children during nutritional rehabilitation, were measured. The serum osteocalcin of all kwashiorkor children was dramatically decreased on admission to hospital, but increased fourfold during rehabilitation. Serum osteocalcin was low in the control group. In both groups these low levels seemed to be independent of those of 1,25-dihydroxyvitamine D3 which were in the normal range. The results suggest that serum osteocalcin levels might be related to protein-energy status.
Unité n. 1, I.N.S.E.R.M., Hôpital Bichat, Paris.
C
C
Prudhon
G
G
Sall
B
B
Ndiaye
D
D
Lemonnier
D001069:Appetite Regulation / Q000502:physiology*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007732:Kwashiorkor / Q000097:blood* / Q000178:diet therapy / Q000534:rehabilitation; D008297:Male; D015675:Osteocalcin / Q000097:blood*
D015675:Osteocalcin
Régulation nutritionnelle de l'ostéocalcine sérique: étude dans le kwashiorkor.