Modeling the kinetics of topically applied ophthalmic agents.
The equations for the ocular pharmacokinetics of topically applied agents are developed in a matrix form which is well suited to numerical solution on small computers. Some sample computations are presented. The technique is relatively simple to extend to additional compartments.
State College of Optometry, State University of New York, New York.
H J
HJ
Wyatt
D000287:Administration, Topical; D005123:Eye / Q000378:metabolism*; D006801:Humans; D008954:Models, Biological; D009883:Ophthalmic Solutions / Q000493:pharmacokinetics*
D009883:Ophthalmic Solutions