Anesthetic management for instrumentation of the pregnant rhesus monkey.
The anesthetic procedures used and the responses observed during maternal instrumentation on 38 pregnant rhesus monkeys (Macaca mulatta) during the second half of gestation are reported. A laparotomy with maternal instrumentation was performed in all animals. Anesthesia was induced with ketamine and maintained with halothane. Two animals delivered within five days of anesthesia and surgery and were unable to undergo experimentation. The remaining 36 animals underwent successful experimentation. Dysrhythmias, hypotension, and hypothermia were identified as complications of anesthesia.
Department of Physiology, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.
E A
EA
Sanders
R D
RD
Gleed
P W
PW
Nathanielsz
D000768:Anesthesia, General / Q000662:veterinary*; D000769:Anesthesia, Inhalation; D000818:Animals; D001784:Blood Gas Analysis / Q000662:veterinary; D001794:Blood Pressure / Q000187:drug effects; D002404:Catheterization / Q000662:veterinary; D005260:Female; D005865:Gestational Age; D006221:Halothane; D006339:Heart Rate / Q000187:drug effects; D007103:Immobilization; D007649:Ketamine; D007813:Laparotomy / Q000662:veterinary; D008253:Macaca mulatta / Q000502:physiology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011270:Pregnancy, Animal / Q000502:physiology*; D012149:Restraint, Physical / Q000662:veterinary
D007649:Ketamine; D006221:Halothane