Prostate irradiation does not affect the serum prostatic acid phosphatase level.
Twenty-nine consecutive patients with localized prostatic carcinoma were studied prospectively to assess the effect of radical pelvic irradiation on the serum prostatic acid phosphatase level (SPAPL). The doses of radiation given ranged from 64.00 to 66.00 Gy. SPAPLs were taken before, during and shortly after their treatment. No significant individual variations in SPAPLs were found. When patients with prostatic carcinoma show rises in serum prostatic acid phosphatase during or after pelvic irradiation, these are unlikely to be due to their treatment and occult pelvic nodal or bony disease should be considered.
Wellington Hospital, New Zealand.
D R
DR
Christie
N A
NA
Spry
S
S
Marshall
D S
DS
Lamb
D000135:Acid Phosphatase / Q000097:blood*; D006801:Humans; D008297:Male; D011467:Prostate / Q000201:enzymology*; D011471:Prostatic Neoplasms / Q000201:enzymology / Q000532:radiotherapy*
D000135:Acid Phosphatase