title: Variations in healing of infrabony defects treated with ceramic bone-grafting material observed radiographically for a period of three years.
abstract: This study has observed the radiographic changes occurring after surgical treatment of areas of severe periodontal destruction with bone loss. Regions designated test sites were grafted with Periograf (Durapatite) and compared with non-grafted control sites over a three-year period, by use of a standardized radiographic alignment technique. Variations in the healing of both the grafted and non-grafted sites were observed, and it was concluded that regeneration of infrabony defects which had received grafting material can occur over a protracted period of time, which may be different in different individuals, and in different parts of the mouth within the same individual. In addition, periodontal destruction may occur as a slowly progressive condition, or in acute bursts of activity at different times, and at different rates in different parts of the mouth. Furthermore, some defects may be associated with active destructive periodontal disease, with adjacent areas concurrently demonstrate healing radiographically.
authors.affiliation: University College Hospital, London, England.
authors.forename: P N
authors.initials: PN
authors.lastname: Galgut
mesh_terms: D001861:Bone Regeneration; D002516:Ceramics; D017886:Durapatite; D005260:Female; D006801:Humans; D006882:Hydroxyapatites; D008297:Male; D008875:Middle Aged; D010510:Periodontal Diseases / Q000000981:diagnostic imaging / Q000601:surgery*; D019736:Prostheses and Implants; D011859:Radiography; D014945:Wound Healing
chemical_list: D006882:Hydroxyapatites; D017886:Durapatite