Serum concentrations of pregnancy-associated alpha-2-glycoprotein in diabetic pregnancy complicated by nonfulminant and fulminant proliferative retinopathy.
The pregnancy zone protein serum concentration in normal pregnancy reaches its peak at about the 24th week. High serum PZ concentrations are significantly more frequent among pregnant diabetic patients without proliferative retinopathy. In contrast, the mean values in mothers with diabetes mellitus complicated by proliferative retinopathy continue to decrease. A very low limit of 150 mg/l was achieved more frequently in diabetic pregnancy complicated by fulminant proliferative retinopathy. Measurement of serum PZ levels in diabetic pregnancy might help to predict the risk of progressive retinopathy.
Briese
V
V
Clinic of Obstetrics and Gynecology, Medical School, Rostock University, Germany.
Straube
W
W
Glöckner
E
E
D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000737:chemistry; D003930:Diabetic Retinopathy / Q000097:blood*; D005260:Female; D006801:Humans; D005779:Immunodiffusion; D011237:Predictive Value of Tests; D011247:Pregnancy; D011257:Pregnancy Proteins / Q000737:chemistry*; D011254:Pregnancy in Diabetics / Q000097:blood*; D011379:Prognosis; D012307:Risk Factors
D001786:Blood Glucose; D011257:Pregnancy Proteins