Effect of xamoterol on haemodynamics and plasma catecholamines in chronic heart failure.
The effects of xamoterol on haemodynamics and plasma catecholamines were studied at rest and after exercise in patients with mild to moderate heart failure, using a symptom-limited exercise test. Exercise duration and myocardial efficiency were significantly increased, and heart rate on maximal exercise was reduced despite increased catecholamine levels.
Ollivier
J P
JP
Department of Cardiology, Hôpital Militaire du Val-de-Crâce, Paris, France.
Ricordei
I
I
Bayon
P
P
Popelard
P
P
Moyse
D
D
de Bourayne
J
J
Dupont
C
C
Droniou
J
J
D000318:Adrenergic beta-Agonists / Q000494:pharmacology*; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects*; D002303:Cardiac Output, Low / Q000097:blood*; D002395:Catecholamines / Q000097:blood*; D002908:Chronic Disease; D004311:Double-Blind Method; D015444:Exercise / Q000502:physiology; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011412:Propanolamines / Q000494:pharmacology*; D017307:Xamoterol
D000318:Adrenergic beta-Agonists; D002395:Catecholamines; D011412:Propanolamines; D017307:Xamoterol