title: Detection of carcinogenic glutamic acid pyrolysis products in cigarette smoke condensate.
abstract: Carcinogenic glutamic acid pyrolysis products were measured in condensate of cigarette mainstream smoke by HPLC. These carcinogens were found to be present in all brands of filter-tipped cigarette analyzed. The mean levels of 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole and 2-aminodipyridol[1,2-a:3',2'-d]imidazole in the cigarette mainstream smoke were 0.66 and 0.63 ng/cig respectively.
authors.affiliation: Department of Hygiene and Preventive Medicine, Faculty of Medicine, University of Tokyo, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Kanai
authors.forename: O
authors.initials: O
authors.lastname: Wada
authors.forename: S
authors.initials: S
authors.lastname: Manabe
mesh_terms: D002273:Carcinogens / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D005971:Glutamates; D018698:Glutamic Acid; D007093:Imidazoles / Q000032:analysis*; D007564:Japan; D013058:Mass Spectrometry; D009153:Mutagens / Q000032:analysis*; D012906:Smoke / Q000032:analysis*; D012907:Smoking; D014481:United States
chemical_list: D002273:Carcinogens; D005971:Glutamates; D007093:Imidazoles; D009153:Mutagens; D012906:Smoke; D018698:Glutamic Acid; C023785:2-amino-6-methyldipyrido(1,2-a-3',2'-d)imidazole; C023847:Glu-P-2