title: A comparative study of the biological properties of krait (genus Bungarus) venoms.
abstract: 1. The intravenous median lethal doses (LD50), protease, phosphodiesterase, alkaline phosphomonoesterase, L-amino acid oxidase, acetylcholinesterase, phospholipase A, 5'-nucleotidase, hyauronidase and anticoagulant activities of fourteen samples of venoms from the four common species of krait (Bungarus caeruleus, Bungarus candidus, Bungarus multicinctus and Bungarus fasciatus) were examined. 2. The results indicate that even though there are individual variations in the biological properties of the krait venoms, interspecific differences in the properties can be used for differentiation of the venoms from the four species of Bungarus. Particularly useful for this purpose are the LD50's and the contents of 5'-nucleotidase and hyaluronidase of the venoms.
authors.affiliation: Department of Biochemistry, University of Malaya, Kuala Lumpur.
authors.forename: N H
authors.initials: NH
authors.lastname: Tan
authors.forename: G
authors.initials: G
authors.lastname: Ponnudurai
mesh_terms: D015720:5'-Nucleotidase / Q000378:metabolism; D000110:Acetylcholinesterase / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000378:metabolism; D000594:Amino Acid Oxidoreductases / Q000378:metabolism; D000818:Animals; D000925:Anticoagulants; D002265:Carboxylic Ester Hydrolases / Q000378:metabolism; D003029:Coagulants; D004546:Elapid Venoms / Q000494:pharmacology*; D006470:Hemorrhage / Q000139:chemically induced; D006821:Hyaluronoglucosaminidase / Q000378:metabolism; D050830:L-Amino Acid Oxidase; D007928:Lethal Dose 50; D051379:Mice; D010447:Peptide Hydrolases / Q000378:metabolism; D010741:Phospholipases A / Q000378:metabolism; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism; D013045:Species Specificity
chemical_list: D000925:Anticoagulants; D003029:Coagulants; D004546:Elapid Venoms; D000594:Amino Acid Oxidoreductases; D050830:L-Amino Acid Oxidase; C019724:arginine esterase; D002265:Carboxylic Ester Hydrolases; D010741:Phospholipases A; D000110:Acetylcholinesterase; D000469:Alkaline Phosphatase; D015720:5'-Nucleotidase; D010727:Phosphoric Diester Hydrolases; D006821:Hyaluronoglucosaminidase; D010447:Peptide Hydrolases