title: Immunosuppression elicited by stressors and stressor-related odors.
abstract: Exposure of footshock 72 h after administration of sheep red blood cells (SRBC) provoked a reduction of the splenic plaque-forming cell (PFC) response and plasma antibody titers in CD-1 mice. At this time following SRBC inoculation the antibody titers and PFC response were also modifiable by nonpainful stressors, such as the presentation of a weak light or odor cues of conspecifics that had been exposed to a stressor (light). Data are discussed in terms of the sensitivity of the immune response to environmental and psychological stressors, and the implications of this particular sensitivity to further analyses of stressor effects on immune activity.
authors.affiliation: Department of Psychology, Carleton University, Ottawa, Ontario, Canada.
authors.forename: S
authors.initials: S
authors.lastname: Zalcman
authors.forename: L
authors.initials: L
authors.lastname: Kerr
authors.forename: H
authors.initials: H
authors.lastname: Anisman
mesh_terms: D000818:Animals; D000917:Antibody Formation; D003214:Conditioning, Classical; D004597:Electroshock; D017707:Erythrocyte Transfusion; D004912:Erythrocytes / Q000276:immunology; D006388:Hemagglutinins / Q000096:biosynthesis; D006462:Hemolytic Plaque Technique; D007108:Immune Tolerance; D007274:Injections, Intraperitoneal; D008297:Male; D051379:Mice; D009812:Odorants; D010775:Photic Stimulation / Q000009:adverse effects; D012756:Sheep / Q000097:blood; D013312:Stress, Physiological / Q000209:etiology / Q000276:immunology* / Q000503:physiopathology; D014183:Transplantation, Heterologous
chemical_list: D006388:Hemagglutinins