Confirmed rabies exposure during pregnancy: treatment with human rabies immune globulin and human diploid cell vaccine.
A review of the literature shows 24 cases of pregnant human exposure to rabies virus through confirmed rabid animal bites. Historically, these patients received passive immunization with equine rabies immunoglobulin and/or purified vero cell vaccine or duck embryo vaccine. With the recent development of human-derived rabies vaccines, we report an additional case of human gestational rabies exposure, which was treated with human rabies immune globulin and human diploid cell vaccine.
Chabala
S
S
Henry Ford Hospital-Fairlane, Dearborn, Michigan.
Williams
M
M
Amenta
R
R
Ognjan
A F
AF
D000328:Adult; D005260:Female; D006801:Humans; D007116:Immunization, Passive / Q000592:standards*; D007136:Immunoglobulins / Q000008:administration & dosage* / Q000097:blood; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000097:blood / Q000453:epidemiology / Q000628:therapy*; D011256:Pregnancy Outcome; D011818:Rabies / Q000097:blood / Q000453:epidemiology / Q000628:therapy*; D011819:Rabies Vaccines / Q000008:administration & dosage / Q000627:therapeutic use*
D007136:Immunoglobulins; D011819:Rabies Vaccines