title: Effect of estradiol on spermatogenesis and testicular hydroxysteroid dehydrogenase activities in Bidder's organectomized toad (Bufo melanostictus).
abstract: Inhibition of spermatogenic activity and increase in Leydig Cell nuclear area (L C N A), testicular delta 5-3 beta-hydroxysteroid dehydrogenase (delta 5-3 beta-HSD) and 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) activities were noted after Bidder's organectomy. Administration of estradiol in Bidder's organectomized toad showed more or less similar result as the control animal. It is supposed that estradiol coming from the Bidder's organ might play a role in normal testicular activities.
authors.affiliation: Department of Physiology, Katwa College, West Bengal, India.
authors.forename: A K
authors.initials: AK
authors.lastname: Ghosh
mesh_terms: D015067:17-Hydroxysteroid Dehydrogenases / Q000378:metabolism*; D015096:3-Hydroxysteroid Dehydrogenases / Q000378:metabolism*; D000818:Animals; D002023:Bufo bufo; D004958:Estradiol / Q000494:pharmacology*; D007985:Leydig Cells / Q000187:drug effects; D008297:Male; D013091:Spermatogenesis / Q000187:drug effects*; D013737:Testis / Q000201:enzymology*
chemical_list: D004958:Estradiol; D015067:17-Hydroxysteroid Dehydrogenases; D015096:3-Hydroxysteroid Dehydrogenases