[Evaluation of dipotassium clorazepate in pre-anesthetic medication].
The anxiolytic action of clorazepate 15 mg PO on the eve and 1 hour before the surgical procedure was studied in 50 ASA class 1 patients (18-60 years old, 46-86 kg) scheduled for elective non-oncological surgery. Anxiety, assessed by the anaesthetist employing a modified Hamilton Anxiety Scale, was lower after premedication in 46 patients (p less than 0.01) and only few side-effects were noted. As a conclusion we suggested that clorazepate PO as anaesthetic premedication is suitable for anxiety relief.
Seabra
M
M
Serviço de Anestesia, Hospital Geral de Santo António, Porto.
Esteves
S
S
Diaz
J
J
Sanmartin
D
D
Araújo
M S
MS
D000328:Adult; D001007:Anxiety / Q000188:drug therapy*; D003009:Clorazepate Dipotassium / Q000627:therapeutic use*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011229:Preanesthetic Medication
D003009:Clorazepate Dipotassium
Avaliação do clorazepato dipotãssico em medicação pré-anestésica.