Collection of PBSC with Fenwal CS-3000 for autografting.
The peripheral blood represents an alternative source of haemopoietic progenitors and permits autografting in patients who have contraindications for a bone marrow harvest but who are otherwise candidates for autologous bone marrow transplantation. Circulating stem cells can be harvested performing several leucaphereses during the overshoot after a mobilization chemotherapy. The use of Fenwal CS-3000 cell separator allows reproducibility from donor to donor and makes the procedure very efficient. We collected peripheral blood stem cells (PBSC) in four patients, 2 with Hodgkin's lymphoma, 1 with high-grade non-Hodgkin's lymphoma and 1 with secondary FAB unclassifiable ANLL: the procedures of collection and cell harvests obtained are reported.
Indovina
A
A
Divisione di Ematologia, Ospedale V Cervello, Palermo, Italy.
Scimè
R
R
Vasta
S
S
Magrin
S
S
Hauser
D
D
Gentile
S
S
Santoro
A
A
Felice
R
R
Majolino
I
I
D000328:Adult; D001800:Blood Specimen Collection / Q000379:methods*; D002469:Cell Separation / Q000379:methods*; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D014182:Transplantation, Autologous