title: Rejection-associated upregulation of the alpha/beta-T cell receptor expression on T cells of renal allograft recipients.
abstract: Peripheral T lymphocytes of renal allograft recipients were phenotyped for their expression of the CD3-T cell receptor (TCR) complex. The majority of T cells from patients with stable graft function had normal CD3 but diminished TCR alpha/beta heterodimer expression, while TCR gamma/delta + T cells were increased in some cases. Acute rejection was associated with an increase in TCR alpha/beta + T cells to normal levels.
authors.affiliation: Transplantation Institute, Warsaw Medical School, Poland.
authors.forename: A
authors.initials: A
authors.lastname: Górski
authors.forename: M
authors.initials: M
authors.lastname: Nowaczyk
authors.forename: M
authors.initials: M
authors.lastname: Małdyk
authors.forename: J
authors.initials: J
authors.lastname: Juskowa
authors.forename: J
authors.initials: J
authors.lastname: Wyzgał
authors.forename: M
authors.initials: M
authors.lastname: Modlińska
authors.forename: J
authors.initials: J
authors.lastname: Bukowska
authors.forename: M
authors.initials: M
authors.lastname: Morzycka-Michalik
mesh_terms: D006084:Graft Rejection / Q000187:drug effects; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016030:Kidney Transplantation / Q000276:immunology*; D016693:Receptors, Antigen, T-Cell, alpha-beta / Q000096:biosynthesis*; D016176:T-Lymphocyte Subsets / Q000187:drug effects; D015854:Up-Regulation
chemical_list: D007166:Immunosuppressive Agents; D016693:Receptors, Antigen, T-Cell, alpha-beta