title: High-dose oral baclofen: experience in patients with multiple sclerosis.
abstract: We reviewed a 10% random sample of charts from an outpatient clinic for multiple sclerosis to determine the frequency with which baclofen was prescribed for spasticity in high doses (greater than 80 mg/d). About 20% of patients had taken high-dose baclofen, and 15% were still receiving a high dose. Taking a high dose was not associated with discontinuing treatment.
authors.affiliation: Medical Rehabilitation Research and Training Center for Multiple Sclerosis, Albert Einstein College of Medicine, Bronx, NY 10461.
authors.forename: C R
authors.initials: CR
authors.lastname: Smith
authors.forename: N G
authors.initials: NG
authors.lastname: LaRocca
authors.forename: B S
authors.initials: BS
authors.lastname: Giesser
authors.forename: L C
authors.initials: LC
authors.lastname: Scheinberg
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D001418:Baclofen / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000188:drug therapy*; D009128:Muscle Spasticity / Q000188:drug therapy
chemical_list: D001418:Baclofen