[Studies on the toxic constituents of Illicium simonsii Maxim].
A new sesquiterpenelactone compound was isolated along with the known anisatin and shikimic acid from pericarps of the fruit of Illicium simonsii Maxim., family Magnoliaceae, collected in Sichuan province. This new sesquiterpene lactone compound exhibited high toxicity in mice. The structure of which was elucidated as 2-oxo-6-deoxyneoanisatin (I) based on spectral evidences. The detailed physical and chemical data were presented.
Yang
C S
CS
Faculty of Chinese Pharmacy, Beijing College of Traditional Chinese Medicine.
Wang
J L
JL
Zhang
Z L
ZL
Kouno
I
I
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D007783:Lactones; D051379:Mice; D010945:Plants, Edible / Q000737:chemistry*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000627:therapeutic use; D012765:Shikimic Acid / Q000302:isolation & purification; D013141:Spiro Compounds / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity
D004365:Drugs, Chinese Herbal; D007783:Lactones; D012717:Sesquiterpenes; D013141:Spiro Compounds; C064099:2-oxo-6-dehydroxyneoanisatin; D012765:Shikimic Acid; C031244:anisatin