title: [Experimental parvovirus infection of puppies: immunohistological findings].
abstract: Formalin-fixed tissue samples obtained from puppies experimentally infected with canine parvovirus type 2 (CPV-2) were investigated immunohistologically with the direct immunoperoxidase method. Besides cardiac muscle and lymphatic tissues, bone marrow, intestine, liver, kidney, pancreas and to a lesser degree lung stained positive for viral antigen and are considered as sites of viral replication. The distribution of viral antigen reveals a tropism of CPV-2 to numerous organs in puppies infected during the first week of life.
authors.affiliation: Institut für Pathologie der Tierärztlichen Fakultät Thessaloniki, Griechenland.
authors.forename: I
authors.initials: I
authors.lastname: Vlemmas
authors.forename: P
authors.initials: P
authors.lastname: Wohlsein
authors.forename: G
authors.initials: G
authors.lastname: Trautwein
authors.forename: G
authors.initials: G
authors.lastname: Kanakudis
authors.forename: T
authors.initials: T
authors.lastname: Tsangaris
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000032:analysis*; D004283:Dog Diseases / Q000382:microbiology*; D004285:Dogs; D007150:Immunohistochemistry; D010321:Parvoviridae / Q000276:immunology* / Q000502:physiology; D010322:Parvoviridae Infections / Q000382:microbiology / Q000662:veterinary*; D014779:Virus Replication
chemical_list: D000956:Antigens, Viral
vernacular_title: Experimentelle Parvovirusinfektion von Hundewelpen: Immunohistologische Befunde.