title: An experimental intraarticular implantation of woven carbon fiber pad into osteochondral defect of the femoral condyle in rabbit.
abstract: The defects of the articular cartilage structure are not replaced unless the subchondral plate has been breached. However, following the creation of a defect in the subchondral plate, the area is filled in with a fibrous tissue which gradually transforms to hyaline cartilage. The porous nontoxic materials of both biologic and synthetic origin have reportedly been used as matrices for repairing bone and cartilage. Following implantation, carbon fibre, chemically inert and well-tolerated by the body, induces a proliferation of ordered fibrous tissue. We implanted carbon fiber pads in osteochondral defects in rabbits. Those repairs were compared to control holes with no implants. The pads appeared to induce the gross appearance of a restored joint surface, mechanically strong to loading for periods from 2 to 6 weeks. Also, carbon fiber pads promoted the healing of the osteochondral defects in the rabbit femoral condyle, supplying well-organized cartilagenous tissue over repaired subchondral bone. The use of carbon fiber pads as implant material is suggested for the restoration of articular surface in osteoarthritis and osteochondritis dissecans.
authors.affiliation: Department of Orthopaedic Surgery, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea.
authors.forename: H J
authors.initials: HJ
authors.lastname: Kang
authors.forename: C D
authors.initials: CD
authors.lastname: Han
authors.forename: E S
authors.initials: ES
authors.lastname: Kang
authors.forename: N H
authors.initials: NH
authors.lastname: Kim
authors.forename: W I
authors.initials: WI
authors.lastname: Yang
mesh_terms: D000818:Animals; D002244:Carbon; D000077482:Carbon Fiber; D002358:Cartilage, Articular / Q000601:surgery / Q000648:ultrastructure*; D007719:Knee Joint / Q000601:surgery / Q000648:ultrastructure*; D008855:Microscopy, Electron, Scanning; D019736:Prostheses and Implants; D011817:Rabbits
chemical_list: D000077482:Carbon Fiber; D002244:Carbon