title: The domestic goat: a useful model to determine effects of diet and exercise on cholesterol accumulation in the body.
abstract: 1. Young goats were used to study factors contributing to atherosclerosis. 2. Cholesterol in egg yolk affected plasma cholesterol concentration more than did a similar amount of crystalline cholesterol in the diet. 3. Goats fed high fat diets developed fatty lesions in their aortas. 4. Cholesterol concentration in low-density lipoprotein was greatest in goats fed restricted-calorie diets without exercise, but least in goats fed liberally and exercised. 5. Cholesterol concentration in liver and fat deposition in aorta were greatest in the restricted-calorie, no exercise regime.
authors.affiliation: Department of Animal Science, Iowa State University, Ames 50011.
authors.forename: M J
authors.initials: MJ
authors.lastname: Richard
authors.forename: L D
authors.initials: LD
authors.lastname: Davis
authors.forename: N L
authors.initials: NL
authors.lastname: Jacobson
mesh_terms: D000818:Animals; D001161:Arteriosclerosis / Q000209:etiology* / Q000378:metabolism; D001835:Body Weight / Q000502:physiology; D002784:Cholesterol / Q000097:blood / Q000378:metabolism*; D002791:Cholesterol, Dietary / Q000494:pharmacology*; D004195:Disease Models, Animal; D006041:Goats / Q000378:metabolism*; D005082:Physical Exertion / Q000502:physiology*
chemical_list: D002791:Cholesterol, Dietary; D002784:Cholesterol