title: Separation of hydroxyquinolines by high-performance liquid chromatography.
abstract: 1. Hydroxyquinolines are important chemicals for pharmaceutical and cosmetic use. This report describes an improved method for separating these chemicals, by utilizing a high-performance liquid chromatography technique. 2. 8-Hydroxyquinoline is an excellent chelating agent. Previous separation procedures failed because of this property. An important requirement for the success of the method described is to provide a metal-free environment for the separation of hydroxyquinolines by replacing metal tubing with Polyplex and polyether-ether ketone (PEEK) tubing and utilizing a metal-free Hamilton PRP-1 column.
authors.affiliation: American Health Foundation, Valhalla, New York 10595-1599.
authors.forename: I
authors.initials: I
authors.lastname: Nagiel-Ostaszewski
authors.forename: M T
authors.initials: MT
authors.lastname: Vavrek
authors.forename: J H
authors.initials: JH
authors.lastname: Weisburger
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006912:Hydroxyquinolines / Q000302:isolation & purification*; D011804:Quinolines / Q000302:isolation & purification; D013056:Spectrophotometry, Ultraviolet / Q000379:methods
chemical_list: D006912:Hydroxyquinolines; D011804:Quinolines; C037219:quinoline