[A possible way to diagnose and treat AIDS with low-molecular nonpeptide substances that specifically block the CD4 receptor of the lymphocytes and the gp120 receptor of the virus].
Piruzian
L A
LA
Kovalev
I E
IE
Dement'eva
V A
VA
D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism; D000998:Antiviral Agents / Q000627:therapeutic use; D015704:CD4 Antigens / Q000037:antagonists & inhibitors*; D015496:CD4-Positive T-Lymphocytes / Q000187:drug effects* / Q000378:metabolism; D015699:HIV Envelope Protein gp120 / Q000037:antagonists & inhibitors*; D006801:Humans; D008024:Ligands; D008970:Molecular Weight; D011485:Protein Binding / Q000187:drug effects; D015728:Receptors, HIV / Q000187:drug effects* / Q000378:metabolism; D012995:Solubility
D000998:Antiviral Agents; D015704:CD4 Antigens; D015699:HIV Envelope Protein gp120; D008024:Ligands; D015728:Receptors, HIV
Vozmozhnyĭ put' diagnostiki i lecheniia SPIDa nizkomolekuliarnymi nepeptidnymi veshchestvami, spetsificheski blokiruiushchimi CD4-retseptor limfotsitov i gp120-retseptor virusa.