Transient epidermal necrosis associated with disseminated intravascular coagulation in a patient with urticaria.
A patient with intermittent erythema developed urticaria and a systemic illness associated with the development of disseminated intravascular coagulation and a widespread bullous eruption. A skin biopsy showed intravascular fibrin and epidermal necrosis with no evidence of vasculitis. The patient made a complete recovery following therapy with fresh frozen plasma and platelets and pulsed intravenous methylprednisolone.
Camilleri
J P
JP
Department of Rheumatology, University Hospital of Wales, Heath Park, Cardiff, U.K.
Finlay
A Y
AY
Douglas-Jones
A G
AG
Kitching
P A
PA
Williams
B D
BD
D000328:Adult; D004211:Disseminated Intravascular Coagulation / Q000150:complications* / Q000473:pathology; D005260:Female; D005528:Foot; D006801:Humans; D009336:Necrosis; D012867:Skin / Q000473:pathology*; D012872:Skin Diseases, Vesiculobullous / Q000150:complications* / Q000473:pathology; D014581:Urticaria / Q000150:complications* / Q000473:pathology