title: [The effects of a dietary fiber (white lupine bran) in the treatment of non-insulin-dependent diabetes].
abstract: We evaluated the effect of dietary fiber from sweet lupine hull (SLH) upon metabolic control in 16 non insulin dependent diabetics (11 males, mean age 52). Body mass index was 23 +/- 2 and non fasting glucose levels were < 200 mg/dl. Following a 2 month control period, patients received SLH, 10 g th 3rd month and 20 g the fourth. Eleven patients received in addition oral hypoglycemic drugs. Intake of crude dietary fiber increased from 4.1 +/- 1.7 to 8.4 +/- 2 and 13.1 +/- 1 g from control to the 3rd and 4th month. Blood glucose increased and cholesterol level decreased in the 3rd month (p < 0.05). During the 4th month, blood glucose decreased to control levels. No changes were observed in body mass, HDL cholesterol, triglycerides, glycosylated Hb and non-fasting glucose and insulin levels in relation to fiber intake. We conclude that dietary fiber intake is low in our patients but a supplement of 10 to 20 g of this particular fiber did not improve metabolic control.
authors.affiliation: Departamento de Medicina, Hospital San Juan de Dios, Universidad de Chile, Santiago.
authors.forename: J
authors.initials: J
authors.lastname: Díaz
authors.forename: P
authors.initials: P
authors.lastname: Durruty
authors.forename: J C
authors.initials: JC
authors.lastname: Tapia
authors.forename: E
authors.initials: E
authors.lastname: Carrasco
authors.forename: V
authors.initials: V
authors.lastname: Riesco
authors.forename: G
authors.initials: G
authors.lastname: Durruty
authors.forename: M
authors.initials: M
authors.lastname: García de los Ríos
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001786:Blood Glucose / Q000032:analysis / Q000187:drug effects; D016009:Chi-Square Distribution; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000178:diet therapy* / Q000453:epidemiology; D004043:Dietary Fiber / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis / Q000187:drug effects; D006801:Humans; D007328:Insulin / Q000097:blood; D008297:Male; D008875:Middle Aged; D010945:Plants, Edible; D013997:Time Factors
chemical_list: D001786:Blood Glucose; D004043:Dietary Fiber; D006442:Glycated Hemoglobin; D007328:Insulin
vernacular_title: Efectos de una fibra dietaria (salvado de lupino dulce) en el tratamiento de la diabetes no insulinodependiente.