title: Challenges in the design of trials to evaluate antibacterial agents in serious infections.
authors.affiliation: Department of Infectious Diseases, University of Lund, Sweden.
authors.forename: S R
authors.initials: SR
authors.lastname: Norrby
mesh_terms: D002442:Ceftazidime / Q000008:administration & dosage / Q000627:therapeutic use*; D015377:Cilastatin / Q000008:administration & dosage / Q000627:therapeutic use*; D003428:Cross Infection / Q000175:diagnosis / Q000188:drug therapy*; D004338:Drug Combinations; D005060:Europe; D005260:Female; D006801:Humans; D015378:Imipenem / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D015337:Multicenter Studies as Topic; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D012107:Research Design; D014552:Urinary Tract Infections / Q000175:diagnosis / Q000188:drug therapy*
chemical_list: D004338:Drug Combinations; D015377:Cilastatin; D015378:Imipenem; D002442:Ceftazidime