[Immune mechanisms of resistance in mice to the Western equine encephalomyelitis virus].
Using the immunogenetic method and method of immunomodification of outbred animals, it was established that immune response of humoral or cell-mediated type to WEE virus antigens did not play any important role in the survival of intact mice infected with WEE virus. Under such conditions, it is inexpedient to select immune response modulators. The immune response of predominantly cell-mediated type is a determining factor of resistance to WEE virus in mice after immunization started 7 days before challenge of the animals.
Nesterchuk
S L
SL
Posevaia
T A
TA
Barinskiĭ
I F
IF
D000818:Animals; D000833:Animals, Suckling; D000914:Antibodies, Viral / Q000097:blood; D003524:Cyclosporins / Q000494:pharmacology; D004664:Encephalitis Virus, Japanese / Q000276:immunology*; D004672:Encephalitis, Japanese / Q000276:immunology*; D005838:Genotype; D007113:Immunity, Innate / Q000187:drug effects / Q000276:immunology; D007114:Immunization; D008213:Lymphocyte Activation / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology
D000914:Antibodies, Viral; D003524:Cyclosporins
Immunnye mekhanizmy rezistentnosti mysheĭ k virusu zapadnogo éntsefalomielita loshadeĭ.