title: Chronic administration of negative modulators produces chemical kindling and GABAA receptor down-regulation.
authors.affiliation: Department of Experimental Biology, University of Cagliari, Italy.
authors.forename: M G
authors.initials: MG
authors.lastname: Corda
authors.forename: O
authors.initials: O
authors.lastname: Giorgi
authors.forename: M
authors.initials: M
authors.lastname: Orlandi
authors.forename: B
authors.initials: B
authors.lastname: Longoni
authors.forename: G
authors.initials: G
authors.lastname: Biggio
mesh_terms: D000818:Animals; D001643:Bridged Bicyclo Compounds / Q000378:metabolism; D019086:Bridged Bicyclo Compounds, Heterocyclic; D002243:Carbolines / Q000494:pharmacology; D003292:Convulsants / Q000378:metabolism / Q000494:pharmacology; D015536:Down-Regulation / Q000187:drug effects; D007696:Kindling, Neurologic / Q000187:drug effects*; D010433:Pentylenetetrazole / Q000494:pharmacology; D010852:Picrotoxin / Q000494:pharmacology; D011963:Receptors, GABA-A / Q000187:drug effects*; D013462:Sulfur Radioisotopes
chemical_list: D001643:Bridged Bicyclo Compounds; D019086:Bridged Bicyclo Compounds, Heterocyclic; D002243:Carbolines; D003292:Convulsants; D010433:Pentylenetetrazole; D010852:Picrotoxin; D011963:Receptors, GABA-A; D013462:Sulfur Radioisotopes; C035874:FG 7142; C037476:tert-butylbicyclophosphorothionate