title: [Evaluation of dipotassium clorazepate in pre-anesthetic medication].
abstract: The anxiolytic action of clorazepate 15 mg PO on the eve and 1 hour before the surgical procedure was studied in 50 ASA class 1 patients (18-60 years old, 46-86 kg) scheduled for elective non-oncological surgery. Anxiety, assessed by the anaesthetist employing a modified Hamilton Anxiety Scale, was lower after premedication in 46 patients (p less than 0.01) and only few side-effects were noted. As a conclusion we suggested that clorazepate PO as anaesthetic premedication is suitable for anxiety relief.
authors.affiliation: Serviço de Anestesia, Hospital Geral de Santo António, Porto.
authors.forename: M
authors.initials: M
authors.lastname: Seabra
authors.forename: S
authors.initials: S
authors.lastname: Esteves
authors.forename: J
authors.initials: J
authors.lastname: Diaz
authors.forename: D
authors.initials: D
authors.lastname: Sanmartin
authors.forename: M S
authors.initials: MS
authors.lastname: Araújo
mesh_terms: D000328:Adult; D001007:Anxiety / Q000188:drug therapy*; D003009:Clorazepate Dipotassium / Q000627:therapeutic use*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011229:Preanesthetic Medication
chemical_list: D003009:Clorazepate Dipotassium
vernacular_title: Avaliação do clorazepato dipotãssico em medicação pré-anestésica.