title: [Neuropsychiatric and vascular manifestations of disseminated lupus erythematosus].
abstract: Disseminated lupus erythematous is an auto-immune disease with systemic manifestations that develops by outbreaks. It's pathogenesis is unknown. The physiopathology jeopardizes auto-immune phenomenon whose most important biological effect is the polyclonal activation of B Lymphocytes. The tissue's lesions are due to several mechanisms, being, perhaps, the deposition of immune complexes of a great value. On account of a young woman with recurrent deep venous thrombosis and neuropsychiatric manifestations the bibliographic data are reviewed, especially those that concern with the etiopathogenesis, treatment and prognosis.
authors.affiliation: Serviço de Medicina 1, Hospital Geral de Santo António, Porto.
authors.forename: J de A
authors.initials: Jde A
authors.lastname: Correia
authors.forename: J A
authors.initials: JA
authors.lastname: Ramada
authors.forename: R N
authors.initials: RN
authors.lastname: Rocha
authors.forename: J M
authors.initials: JM
authors.lastname: Bernardo
mesh_terms: D000293:Adolescent; D001927:Brain Diseases / Q000209:etiology*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D001523:Mental Disorders / Q000209:etiology*; D013924:Thrombophlebitis / Q000209:etiology*
vernacular_title: Manifestações neuropsiquiãtricas e vasculares no lúpus eritematoso disseminado.