[Detection of HBAg in the liver in patients with schistosomiasis complicated by liver carcinoma].
HBsAg and HBcAg were detected in the liver biopsies of 21 patients with schistosomiasis japonica complicated by hepatocellular carcinoma (HCC), 69 patients with advanced schistosomiasis japonica and 25 patients with HCC. The positive rate of HBAg in liver of patients with schistosomiasis complicated by HCC (85.7%) was significantly higher than those with advanced schistosomiasis (56.5%), but similar to that in the group of HCC (80.0%). The location of tumor cells in liver was not related with the distribution of schistosomal ova in patients with schistosomiasis complicated by HCC. The results indicate that complicated HBV infection may be one of the major causes of HCC developed in patients with schistosomiasis japonica.
Li
Z
Z
D006528:Carcinoma, Hepatocellular / Q000150:complications*; D005260:Female; D006509:Hepatitis B / Q000150:complications; D006512:Hepatitis B Core Antigens / Q000032:analysis*; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006801:Humans; D008113:Liver Neoplasms / Q000150:complications*; D008297:Male; D012554:Schistosomiasis japonica / Q000150:complications / Q000276:immunology*
D006512:Hepatitis B Core Antigens; D006514:Hepatitis B Surface Antigens