Serum antibodies to capsular polysaccharide vaccine of group A and C Neisseria meningitidis in military recruits in Italy.
In this study we evaluated, by a standard bactericidal assay, the antibody response to the meningococcal group A and C polysaccharide vaccine used for the immunization programme of the Italian military recruits, compulsory by law since 1987. The percentage of responders, those who developed a four-fold increase in the bactericidal titre to polysaccharide A and C, was 96% and 98%, respectively. No significant side effects were observed after vaccination.
Occhionero
M
M
Laboratorio di Batteriologia e Micologia Medica, Istituto Superiore di Sanità, Roma.
Usai
G
G
Di Martino
M
M
Le Moli
S
S
Stroffolini
T
T
Mastrantonio
P
P
D000907:Antibodies, Bacterial / Q000096:biosynthesis*; D016667:Bacterial Capsules; D001428:Bacterial Vaccines / Q000276:immunology*; D006801:Humans; D007558:Italy; D022401:Meningococcal Vaccines; D008889:Military Personnel; D009345:Neisseria meningitidis / Q000276:immunology*; D011135:Polysaccharides, Bacterial / Q000276:immunology*; D011897:Random Allocation; D014611:Vaccination
D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines; D022401:Meningococcal Vaccines; D011135:Polysaccharides, Bacterial; C039455:capsular polysaccharide, meningococcal group B; C043226:meningococcal group A polysaccharide