title: The influence of stress treatment on femur cortical bone porosity and medullary bone status in Japanese quail selected for high and low blood corticosterone response to stress.
abstract: 1. Femurs taken from Japanese quail (Coturnix coturnix japonica) genetically selected for either exaggerated (HS; high-stress) or reduced (LS; low-stress) blood corticosterone (B) response to unfamiliar environments were examined to determine their cortical bone porosity (CBP; degree of osteoporosis) and medullary bone (MB) status following treatment with or without stress. 2. Femur CBP was elevated in both sexes of stressed, HS-line quail and was attributed directly to the presumably exaggerated blood B responses known to occur in this line as a consequence of the stress treatments used. 3. The increase in CBP in stressed, HS-line birds occurred independently of changes in the numbers of osteoclast cells (CLASTS) associated with cortical bone. 4. Stress treatment was associated with lower CLAST numbers/mm2 of MB and with increased MB accretion. 5. These stress-induced effects were considered to be the consequence of a reduced rate of lay found in stressed quail hens. 6. There was only marginal evidence for a direct effect of B in stimulating MB resorption.
authors.affiliation: Poultry Science Department, Louisiana Agricultural Experiment Station, Louisiana State University Agricultural Center, Baton Rouge 70803.
authors.forename: D G
authors.initials: DG
authors.lastname: Satterlee
authors.forename: E D
authors.initials: ED
authors.lastname: Roberts
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D002452:Cell Count; D003345:Corticosterone / Q000097:blood*; D003370:Coturnix / Q000097:blood / Q000502:physiology*; D005260:Female; D005269:Femur / Q000473:pathology*; D008297:Male; D010010:Osteoclasts / Q000473:pathology; D010024:Osteoporosis / Q000209:etiology* / Q000473:pathology; D011784:Quail / Q000502:physiology*; D013223:Statistics as Topic; D013312:Stress, Physiological / Q000097:blood / Q000150:complications* / Q000473:pathology
chemical_list: D003345:Corticosterone