[Serological markers of viral infections and various indicators of immunity in patients with hemophilia].
The authors have studied the incidence rate for markers of viruses of AIDS (HIV), hepatitis B (HBV) and cytomegalia (CMV), as well as certain parameters of antiinfectious defense in hemophilia patients. A high incidence rate of HBV and CMV markers was established in the investigated patients, and among them no seropositive subjects, by antibodies to HIV, were detected. In the presence of a low incidence rate of chronic HBsAg-carriership in this category of patients, a significant number of immune subjects was observed, that correlated with a relative stability of such immunity parameters as concentration of serum immunoglobulin G and the level of circulating immune complexes.
Golosova
T V
TV
Somova
A V
AV
Margolina
A N
AN
Tupoleva
T A
TA
Vavilova
L M
LM
Kuz'micheva
M Iu
MIu
Likhacheva
E A
EA
Pliushch
O P
OP
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000276:immunology*; D000914:Antibodies, Viral / Q000032:analysis*; D015415:Biomarkers / Q000097:blood; D003165:Complement System Proteins / Q000032:analysis; D003587:Cytomegalovirus / Q000276:immunology*; D003586:Cytomegalovirus Infections / Q000150:complications / Q000276:immunology*; D015497:HIV-1 / Q000276:immunology*; D006467:Hemophilia A / Q000150:complications / Q000276:immunology*; D006509:Hepatitis B / Q000150:complications / Q000276:immunology*; D006515:Hepatitis B virus / Q000276:immunology*; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008297:Male
D000914:Antibodies, Viral; D015415:Biomarkers; D007136:Immunoglobulins; D003165:Complement System Proteins
Serologicheskie markery virusnykh infektsiĭ i nekotorye pokazateli immuniteta u bol'nykh gemofilieĭ.