An interspecific backcross linkage map of mouse chromosome 8.
We have established a 67-cM molecular genetic linkage map of mouse chromosome 8 by interspecific backcross analysis. Genes that were mapped in this study include Act-6, Aprt, Aprt-ps1, Emv-2, Es-N, Hp, Insr, Mt-1, Plat, Psx-8, Ucp, and Zfp-4. New regions of homology were established between mouse chromosome 8 and human chromosomes 8 and 19. A conserved linkage group was identified between mouse chromosome 8 and human chromosome 16. The map will be useful for establishing linkage of other markers to mouse chromosome 8.
Ceci
J D
JD
Mammalian Genetics Laboratory, NCI-Frederick Cancer Research Facility, Maryland 21701.
Justice
M J
MJ
Lock
L F
LF
Jenkins
N A
NA
Copeland
N G
NG
D000818:Animals; D015139:Blotting, Southern; D002874:Chromosome Mapping; D002885:Chromosomes, Human, Pair 16; D002888:Chromosomes, Human, Pair 19; D002898:Chromosomes, Human, Pair 8; D003433:Crosses, Genetic; D015342:DNA Probes; D008040:Genetic Linkage; D006801:Humans; D051379:Mice / Q000235:genetics*; D008810:Mice, Inbred C57BL; D012150:Polymorphism, Restriction Fragment Length
D015342:DNA Probes