title: [Unilateral lung transplantation in terminal pulmonary emphysema].
abstract: Early attempts of single lung transplantation for end-stage chronic obstructive pulmonary disease mostly failed due to a ventilation-perfusion mismatch between the allograft and the contralateral native lung. We performed unilateral lung transplantation in a 39-year-old female with severe pulmonary emphysema and could demonstrate in a one year follow-up that the transplanted lung will be given preference for both--ventilation and perfusion in approximately the same ratio (80%/90%). With improvement of pulmonary preservation, individual adjustment of immunosuppression and detailed monitoring of the transplanted lung unilateral lung transplantation becomes a therapeutical option in patients with severe emphysema.
authors.affiliation: Klinik für Thorax-, Herz- und Gefässchirurgie, Medizinische Hochschule Hannover.
authors.forename: S W
authors.initials: SW
authors.lastname: Hirt
authors.forename: H J
authors.initials: HJ
authors.lastname: Schäfers
authors.forename: T O
authors.initials: TO
authors.lastname: Wagner
authors.forename: M
authors.initials: M
authors.lastname: Hamm
authors.forename: J
authors.initials: J
authors.lastname: Kotzerke
authors.forename: A
authors.initials: A
authors.lastname: Haverich
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008168:Lung / Q000502:physiology; D016040:Lung Transplantation / Q000379:methods*; D011656:Pulmonary Emphysema / Q000601:surgery*; D014692:Ventilation-Perfusion Ratio
chemical_list: D007166:Immunosuppressive Agents
vernacular_title: Einseitige Lungentransplantation bei terminalem Lungenemphysem.