title: Histoacryl glue in microvascular surgery.
abstract: The use of Histoacryl glue in the performance of microvascular anastomosis was examined in a rat model. An improvement in efficiency as noted by the decreased ischemic time and diminished bleeding with clamp removal was noted. Histological examination of the anastomosis at one and three weeks revealed a mild foreign body type inflammatory response to glue and suture material with no media necrosis and only minimal fibrointimal proliferation.
authors.affiliation: Department of Otolaryngology, University of Toronto, Wellesley Hospital, Ontario, Canada.
authors.forename: W G
authors.initials: WG
authors.lastname: Middleton
authors.forename: W
authors.initials: W
authors.lastname: Matthews
authors.forename: D A
authors.initials: DA
authors.lastname: Chiasson
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods*; D000818:Animals; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D004659:Enbucrilate / Q000627:therapeutic use*; D005549:Foreign-Body Reaction / Q000139:chemically induced / Q000473:pathology; D008264:Macrophages / Q000473:pathology; D008866:Microsurgery / Q000379:methods*; D051381:Rats; D011919:Rats, Inbred Strains; D013536:Suture Techniques; D013997:Time Factors; D014654:Vascular Patency; D014656:Vascular Surgical Procedures / Q000379:methods*
chemical_list: D004659:Enbucrilate