The pathobiology of HIV infection. A review.
Human immunodeficiency virus selectively infects lymphocytes and macrophages resulting in profound immunosuppression leading to opportunistic infections. This review deals with the virus/cell interaction and explains the apparent paradox of the global immune defect in the acquired immunodeficiency syndrome of a single subset of lymphocytes.
Smith
R D
RD
Department of Pathology and Laboratory Medicine, University of Cincinnati, Ohio.
D015496:CD4-Positive T-Lymphocytes / Q000473:pathology; D015658:HIV Infections / Q000473:pathology*; D015497:HIV-1; D015498:HIV-2; D006801:Humans; D008264:Macrophages / Q000473:pathology; D009000:Monocytes / Q000473:pathology