title: [The effect of steroidal dominance on cAMP, cGMP, progesterone and 17 beta-estradiol levels in the fluid of the largest follicle].
abstract: Concentrations and mutual correlations of the cyclic adenosin monophosphate (cAMP), quanosin monophosphate (cGMP), progesterone (P4) and 17-beta-estradiol (E2) were studied in the fluid of the largest follicles in cows, in dependence on the steroid dominance: estrogen-dominant (ED), progesterone-dominant (PD) follicles. Mean cAMP and cGMP concentrations in the follicular fluid in the estrogen-dominant follicles were significantly higher than in the progesterone-dominant follicles; in both cases at P less than 0.01. Significant positive correlation between cAMP and cGMP at P less than 0.001 was stated in the evaluation of the correlations. The cAMP and cGMP concentrations were in significantly negative correlations with the P4 concentration at P less than 0.05, or P less than 0.01 and in significantly positive correlations with the E2, at P less than 0.05. The stated correlations suggest a close mutual relation between cyclic nucleotid and E2, or P4 when the follicles' quality changes.
authors.affiliation: Ustav experimentálnej veterinárnej medicíny, Kosice.
authors.forename: L
authors.initials: L
authors.lastname: Lazár
authors.forename: J
authors.initials: J
authors.lastname: Elecko
authors.forename: I
authors.initials: I
authors.lastname: Maracek
mesh_terms: D000818:Animals; D002417:Cattle / Q000378:metabolism*; D000242:Cyclic AMP / Q000032:analysis*; D006152:Cyclic GMP / Q000032:analysis*; D004958:Estradiol / Q000032:analysis*; D005260:Female; D006080:Ovarian Follicle / Q000033:anatomy & histology / Q000737:chemistry*; D011374:Progesterone / Q000032:analysis*
chemical_list: D011374:Progesterone; D004958:Estradiol; D000242:Cyclic AMP; D006152:Cyclic GMP
vernacular_title: Vplyv steroidnej dominancie na koncentrácie cAMP, cGMP, progesterónu a 17 beta-estradiolu v tekutine najväcsieho folikulu.