[Indices of structure and function of erythrocyte membranes in rats with vitamin E deficiency and their correction with antioxidant drugs].
It is found that the amount of saturated fatty acids grows, while that of unsaturated--falls in the erythrocyte membranes of rats maintained on a diet without vitamin E. In this case transmembrane calcium transport catalyzed by Ca2(+)-ATPase (EC 3.6.1.3) is not broken and activity of antioxidant enzyme superoxide dismutase (EC 1.15.1.11) in lysate of erythrocytes falls. The found shifts are corrected with administration of antioxidant preparations.
Poberezkina
N B
NB
Khmelevskiĭ
Iu V
IuV
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001692:Biological Transport / Q000502:physiology; D002118:Calcium / Q000097:blood; D000252:Calcium-Transporting ATPases / Q000378:metabolism; D004910:Erythrocyte Membrane / Q000378:metabolism*; D005227:Fatty Acids / Q000097:blood; D005231:Fatty Acids, Unsaturated / Q000097:blood; D005609:Free Radicals; D008658:Inactivation, Metabolic / Q000502:physiology; D011237:Predictive Value of Tests; D051381:Rats; D013481:Superoxides / Q000493:pharmacokinetics; D014811:Vitamin E Deficiency / Q000097:blood*; D015262:Xenobiotics / Q000493:pharmacokinetics
D000975:Antioxidants; D005227:Fatty Acids; D005231:Fatty Acids, Unsaturated; D005609:Free Radicals; D015262:Xenobiotics; D013481:Superoxides; D000252:Calcium-Transporting ATPases; D002118:Calcium
Pokazateli struktury i funktsii membran érytrotsitov krys s E-vitaminnoĭ nedostatochnost'iu i ikh korrektsiia preparatami antioksidantov.