title: Activity of Na-K-ATPase and Ca-Mg-ATPase in red blood cell membranes of lead-depleted rats.
abstract: Na-K-ATPase and Ca-Mg-ATPase activity of erythrocyte membranes from lead-depleted rats were determined. In P0 generation there was no difference in activity of Na-K-ATPase and Ca-Mg-ATPase between control and depletion rats. In contrast to this, in F1 generation lead-depleted rats showed reduced activity of both enzymes. Possibly, these changes of Na-K-ATPase and Ca-Mg-ATPase activity cause the reduction of the mean corpuscular cell volume (MCV) observed in former lead depletion studies.
authors.affiliation: Institut für Ernährungsphysiologie, Technische Universität München-Weihenstephan, Freising, Fed. Rep. of Germany.
authors.forename: K
authors.initials: K
authors.lastname: Eder
authors.forename: A M
authors.initials: AM
authors.lastname: Reichlmayr-Lais
authors.forename: M
authors.initials: M
authors.lastname: Kirchgessner
mesh_terms: D000818:Animals; D017301:Ca(2+) Mg(2+)-ATPase / Q000097:blood*; D000252:Calcium-Transporting ATPases / Q000097:blood*; D004032:Diet; D004910:Erythrocyte Membrane / Q000201:enzymology*; D005260:Female; D007854:Lead / Q000172:deficiency*; D051381:Rats; D011919:Rats, Inbred Strains; D000254:Sodium-Potassium-Exchanging ATPase / Q000097:blood*
chemical_list: D007854:Lead; D017301:Ca(2+) Mg(2+)-ATPase; D000252:Calcium-Transporting ATPases; D000254:Sodium-Potassium-Exchanging ATPase