title: [Early summer meningoencephalitis vaccination, a preventive medicine measure with high acceptance in Austria].
abstract: The vaccination against Tick-borne encephalitis (TBE) was accepted by the Austrian population on a broad scale. Of the estimated 5 million Austrians at risk of TBE, as of 1987 only 1.7 million were unvaccinated. From the very small number of TBE cases despite vaccination we were able to calculate a protection rate of 95% after 2 vaccinations and of 99% after 3 or more vaccinations. Since 1984 as a consequence of the vaccination campaign a steady decline of TBE could be observed in Austria. More than 10 years ago improved procedures enabled the production of a highly purified vaccine, thus reducing the number of side effects to a minimum. We here present data from 2067 vaccinees who reported on eventual side reactions by means of a questionnaire. The reactions reported did not exceed those which could be expected after application of a placebo vaccine. Due to high immunogenicity of the vaccine a booster effect can be achieved even some years after a missed vaccination, precluding the necessity of beginning a new series.
authors.affiliation: Institut für Virologie, Universität Wien.
authors.forename: C
authors.initials: C
authors.lastname: Kunz
authors.forename: H
authors.initials: H
authors.lastname: Hofmann
authors.forename: H
authors.initials: H
authors.lastname: Dippe
mesh_terms: D000914:Antibodies, Viral / Q000096:biosynthesis; D001317:Austria; D004669:Encephalitis Viruses, Tick-Borne / Q000276:immunology*; D004675:Encephalitis, Tick-Borne / Q000276:immunology / Q000517:prevention & control*; D006801:Humans; D010342:Patient Acceptance of Health Care; D014765:Viral Vaccines / Q000008:administration & dosage* / Q000009:adverse effects / Q000276:immunology
chemical_list: D000914:Antibodies, Viral; D014765:Viral Vaccines
vernacular_title: Die FSME-Impfung, eine Massnahme der Vorsorgemedizin mit hoher Akzeptanz in Osterreich.