title: Imaging of intramedullary tumour spread in osteosarcoma. A comparison of techniques.
abstract: The level of bone resection for osteosarcoma depends on the pre-operative evaluation of the extent of intramedullary tumour. We compared the accuracy of magnetic resonance imaging (MRI), computerised tomography (CT), and isotope bone scanning with the actual extent of the tumour in the resected specimens from 34 patients with primary osteosarcoma of a long bone. The extent of medullary tumour was defined accurately in 23 of 24 MRI scans (96%) and 24 of 32 CT scans (75%). A flexion contracture of a joint close to the tumour was an important cause for inaccurate measurements from both MRI and CT scans. Isotope bone scanning was inaccurate: its role is now confined to detecting skeletal metastases and skip lesions.
authors.affiliation: Cappagh Hospital, Dublin, Republic of Ireland.
authors.forename: S J
authors.initials: SJ
authors.lastname: O'Flanagan
authors.forename: J P
authors.initials: JP
authors.lastname: Stack
authors.forename: H M
authors.initials: HM
authors.lastname: McGee
authors.forename: P
authors.initials: P
authors.lastname: Dervan
authors.forename: B
authors.initials: B
authors.lastname: Hurson
mesh_terms: D000293:Adolescent; D000328:Adult; D001853:Bone Marrow / Q000000981:diagnostic imaging / Q000473:pathology*; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D002648:Child; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012516:Osteosarcoma / Q000175:diagnosis* / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed