title: [Kidney cell damage and liberation of enzymes].
abstract: The pathophysiological and pathobiochemical background of enzymuria in patients with renal involvement in discussed. Selected markers of the human nephron such as angiotensinase-A, aminopeptidase-M, L-gamma-glutamyl-transferase and dipeptidylpeptidase-IV are characterized; inductive as well as ischaemic/toxic events may induce increased shedding of membrane bound marker-enzymes. Pathological enzyme excretion profiles related to defined renal diseases indicate that tissue-proteinuria of renal origin is a potential noninvasive tool for diagnostic purposes.
authors.affiliation: Abteilung Nephrologie, Johann Wolfgang Goethe-Universität, Frankfurt am Main, Bundesrepublik Deutschland.
authors.forename: J E
authors.initials: JE
authors.lastname: Scherberich
mesh_terms: D004798:Enzymes / Q000652:urine*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007668:Kidney / Q000473:pathology; D007674:Kidney Diseases / Q000175:diagnosis* / Q000201:enzymology* / Q000473:pathology; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000201:enzymology / Q000473:pathology; D007677:Kidney Function Tests
chemical_list: D004798:Enzymes
vernacular_title: Nierenzellschädigung und Freisetzung von Enzymen.