[Studies on ocular blood circulation--effects of oxygen on choroidal circulatory disorders].
Experimental choroidal circulatory disorder was induced by diathermy coagulation in albino rabbit to investigate the effect of oxygen on choroidal blood flow in the area. Choroidal blood flow was measured by a hydrogen clearance method using electrolysis before and after the oxygen inhalation. Oxygen was inhaled for 30 minutes at 1 atmosphere using an open mask method in order to stabilize the arterial blood CO2 concentration. After inhalation of oxygen, normal choroidal blood flow showed a 24.9% decrease from control value, but no significant difference was seen in experimental choroidal circulatory disorder. These results suggested that the inner tissue metabolic CO2 inhibited the effect of vascular constriction in hyperoxemia.
Namikawa
Y
Y
Department of Ophthalmology, Jikei University School of Medicine, Minato-ku Japan.
Horiuchi
T
T
Yamada
Y
Y
D000280:Administration, Inhalation; D000818:Animals; D001775:Blood Circulation / Q000187:drug effects; D002829:Choroid / Q000098:blood supply*; D015862:Choroid Diseases / Q000188:drug therapy; D010100:Oxygen / Q000008:administration & dosage / Q000494:pharmacology*; D011817:Rabbits
D010100:Oxygen