Structural studies of the capsular polysaccharide from Actinobacillus pleuropneumoniae serotype 12.
The capsular polysaccharide of A. pleuropneumoniae is composed of 2-acetamido-2-deoxy-D-glucose (3 parts) and phosphate (1 part). The arrangement of these components in the repeating unit was determined by dephosphorylation, methylation, g.l.c.-m.x., and 1D and 2D n.m.r. spectroscopic methods. The polysaccharide was found to be a high molecular weight polymer of repeating trisaccharide units, joined through phosphate diester linkages, having the structure, (formula: see text).
Beynon
L M
LM
Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario.
Richards
J C
JC
Perry
M B
MB
D016977:Actinobacillus pleuropneumoniae / Q000737:chemistry*; D016667:Bacterial Capsules / Q000737:chemistry*; D002240:Carbohydrate Sequence; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D015394:Molecular Structure; D010766:Phosphorylation