Intensive insulin therapy: euglycemia with a price tag.
The benefit of lowering blood glucose levels with intensive insulin therapy, especially with regard to the development and progression of microvascular complications, is still being investigated. Although many studies have demonstrated a correlation between the degree of hyperglycemia and the risk of development of long-term diabetic complications, we still do not know at what level of glycemia that risk occurs. It is hoped the Diabetes Control and Complications Trial will answer the question. Until that time, patients who are candidates for intensive insulin regimen therapies should be educated and trained to regard the prevention of hypoglycemia as the highest priority of their self-care.
Roman
S H
SH
Department of Medicine, Mount Sinai School of Medicine (CUNY), New York 10029.
D001786:Blood Glucose / Q000032:analysis; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000188:drug therapy*; D004334:Drug Administration Schedule; D006801:Humans; D007328:Insulin / Q000008:administration & dosage*; D007332:Insulin Infusion Systems
D001786:Blood Glucose; D007328:Insulin