title: [Clinical study of itraconazole for the treatment of Tinea cruris, Tinea corporis and Tinea pedis interdigital].
abstract: The authors studied 31 patients with Tinea cruris, corporis or pedis interdigital. The patients were treated with 100 mg of itraconazole, once a day, during the lunch, for 15 days. Mycological and clinical evaluations were performed at the pre-treatment, by the end of treatment and 2 weeks after finishing the treatment. The results showed that itraconazole is effective for the treatment of dermatophytosis, at the studied posology, with 100% of mycological cure. Clinical evaluation showed a significant reduction (Friedman test--p less than 0.001) of signs and symptoms.
authors.affiliation: Faculdade de Ciências Médicas da Santa Casa de São Paulo, Brasil.
authors.forename: C
authors.initials: C
authors.lastname: Zaitz
authors.forename: L R
authors.initials: LR
authors.lastname: Ruiz
authors.forename: E M
authors.initials: EM
authors.lastname: Drullis
authors.forename: P
authors.initials: P
authors.lastname: Gurfinkel
authors.forename: M A
authors.initials: MA
authors.lastname: Ciarnuto
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D017964:Itraconazole; D007654:Ketoconazole / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D014005:Tinea / Q000188:drug therapy*; D014008:Tinea Pedis / Q000188:drug therapy
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D007654:Ketoconazole
vernacular_title: Estudo clínico com o uso do itraconazol em tinha crural, tinha do corpo e tinha do pé interdigital.