title: A small airway pressure sensor for humans.
abstract: We developed a small airway pressure sensor for humans. This sensor catheter was introduced to the right lower lobe bronchus through a fiberoptic bronchoscope until the tip was wedged, at which point the bronchoscope was removed. We measured small airway pressure using this sensor. Simultaneously, we measured mouth flow, mouth pressure and transpulmonary pressure by the esophageal balloon technique during tidal breathing. The present method is called an anterograde method. By this method, we obtained central airway resistance and peripheral airway resistance. A significant increase in peripheral airway resistance, compared to normal subjects, has been confirmed as a symptom of chronic obstructive pulmonary disease.
authors.affiliation: Nihon Kohden Corp., Tokyo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Ozawa
authors.forename: Y
authors.initials: Y
authors.lastname: Sugiyama
authors.forename: M
authors.initials: M
authors.lastname: Yanai
authors.forename: K
authors.initials: K
authors.lastname: Sekizawa
authors.forename: T
authors.initials: T
authors.lastname: Ohrui
authors.forename: H
authors.initials: H
authors.lastname: Sasaki
authors.forename: T
authors.initials: T
authors.lastname: Takishima
mesh_terms: D000403:Airway Resistance / Q000502:physiology*; D000818:Animals; D001999:Bronchoscopy; D004285:Dogs; D004867:Equipment Design; D006801:Humans; D066298:In Vitro Techniques; D008173:Lung Diseases, Obstructive / Q000503:physiopathology*; D008365:Manometry / Q000295:instrumentation*; D011312:Pressure; D012016:Reference Values