In CHEF electrophoresis a linear induction of dsb corresponds to a nonlinear fraction of extracted DNA with dose.
A theory for DNA double-strand break (dsb) analysis by pulsed field electrophoresis is presented, based on the size distribution of DNA fragments, which converts an induction of dsb linear with dose into a nonlinear fraction of extractable DNA, in agreement with experimental observations.
Blöcher
D
D
King Faisal Specialist Hospital and Research Centre, Biomedical Physics Department, Riyadh, Saudi Arabia.
D000818:Animals; D006224:Cricetinae; D004247:DNA / Q000032:analysis* / Q000528:radiation effects*; D004586:Electrophoresis / Q000379:methods*; D066298:In Vitro Techniques
D004247:DNA