title: Cognition and cerebral blood flow in lateralised parkinsonism: lack of functional lateral asymmetries.
abstract: Cognitive and cerebral blood flow (CBF) lateral asymmetries have been quantified in 23 right handed patients with lateralised idiopathic Parkinson's disease. Thirteen patients who had predominant right-sided symptoms (RPD) were compared with ten who had predominant left-sided symptoms (LPD). The patient subgroups were matched for age, education, duration of illness, disease severity and medication. Normalised asymmetries scores were calculated from the data obtained with a test battery and SPECT. No correlation was found between laterality of motor Parkinsonian symptoms and cognitive or haemodynamic asymmetry scores.
authors.affiliation: Service de Neurologie, CHU Purpan, Toulouse, France.
authors.forename: A
authors.initials: A
authors.lastname: Agniel
authors.forename: P
authors.initials: P
authors.lastname: Celsis
authors.forename: G
authors.initials: G
authors.lastname: Viallard
authors.forename: J L
authors.initials: JL
authors.lastname: Montastruc
authors.forename: O
authors.initials: O
authors.lastname: Rascol
authors.forename: J F
authors.initials: JF
authors.lastname: Demonet
authors.forename: J P
authors.initials: JP
authors.lastname: Marc-Vergnes
authors.forename: A
authors.initials: A
authors.lastname: Rascol
mesh_terms: D000368:Aged; D001921:Brain / Q000098:blood supply*; D001925:Brain Damage, Chronic / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002540:Cerebral Cortex / Q000098:blood supply; D003704:Dementia / Q000000981:diagnostic imaging / Q000503:physiopathology*; D004292:Dominance, Cerebral / Q000502:physiology*; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000000981:diagnostic imaging / Q000503:physiopathology*; D011877:Radionuclide Imaging; D012039:Regional Blood Flow / Q000502:physiology