title: Hypomandibular faciocranial dysostosis: report of an affected sib and follow-up.
abstract: Hypomandibular faciocranial dysostosis is a condition heretofore described only in a single case. We report the birth of an affected sister along with follow-up information on the initial surviving patient. While a primary error in neural crest development was postulated in this syndrome, subsequently discovered anatomical abnormalities suggest a more complex pathogenesis.
authors.affiliation: Department of Pediatrics, Kansas University Medical School, Kansas City.
authors.forename: R N
authors.initials: RN
authors.lastname: Schimke
authors.forename: K S
authors.initials: KS
authors.lastname: Claflin
authors.forename: J H
authors.initials: JH
authors.lastname: Seguin
authors.forename: T L
authors.initials: TL
authors.lastname: Bennett
authors.forename: B E
authors.initials: BE
authors.lastname: Finley
authors.forename: L M
authors.initials: LM
authors.lastname: Levitch
authors.forename: W M
authors.initials: WM
authors.lastname: Newcomb
mesh_terms: D000015:Abnormalities, Multiple; D002675:Child, Preschool; D003394:Craniofacial Dysostosis; D003398:Craniosynostoses; D005260:Female; D005808:Genes, Recessive; D005881:Gingiva / Q000002:abnormalities; D006801:Humans; D007231:Infant, Newborn; D008334:Mandible / Q000002:abnormalities*; D009432:Neural Crest / Q000002:abnormalities; D013577:Syndrome; D014132:Trachea / Q000002:abnormalities