[Treatment of liver metastatic ovarian cancer with sequential administration of OK-432 and etoposide].
OK-432 and etoposide were administered intravenously to a patient with liver metastasis of ovarian cancer. OK-432 induced IFN-gamma and TNF. SuPS and PPD skin reaction became positive after the therapy. The size of metastatic lesions was reduced significantly (partial response). It is suggested that the combination therapy of OK-432 and etoposide may be effective to the liver metastasis of ovarian cancer.
Yakabe
A
A
Division of Obstetrics and Gynecology, National Yamaguchi Hospital.
Ito
T
T
Hayashi
K
K
Yamashita
S
S
Ito
T
T
Sugino
N
N
D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy / Q000556:secondary*; D005047:Etoposide / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary*; D010051:Ovarian Neoplasms / Q000188:drug therapy* / Q000473:pathology; D010844:Picibanil / Q000008:administration & dosage*
D010844:Picibanil; D005047:Etoposide