Timing of surgery in congenital diaphragmatic hernia. Low mortality after pre-operative stabilisation.
Eighty-six consecutive patients with congenital diaphragmatic hernia presenting within 6 hours of birth to a regional neonatal surgical unit were reviewed. Patients were managed under a policy of delayed surgery which has evolved during the 6-year study period. Overall survival (to leave hospital) was 70.9%. There were only seven postoperative deaths (10.3% of operations). Analysis of the 25 deaths in the light of postmortem findings and published exclusion criteria indicates that the availability of extracorporeal membrane oxygenation would have made little difference to overall survival.
Charlton
A J
AJ
North West Regional Neonatal Surgery Unit, St. Mary's Hospital for Women and Children, Whitworth Park, Manchester.
Bruce
J
J
Davenport
M
M
D004630:Emergencies; D015199:Extracorporeal Membrane Oxygenation; D006548:Hernia, Diaphragmatic / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D007231:Infant, Newborn; D011300:Preoperative Care / Q000379:methods*; D011659:Pulmonary Gas Exchange / Q000502:physiology; D013997:Time Factors