[The effect of thyroid hormones on the stress-induced changes in the coronary blood flow and contractile function of the hypertrophied heart].
The effect of 6-hour immobilization stress on autoregulation and dilatation of the coronary vessels was studied in 54 hypertrophied hearts of female rats before and after thyroidin treatment. The coronary reserve and autoregulation were found to be decreased. Small doses of thyroidin increased the perfusion index, the gain of autoregulation and coronary reserve, and restricted the effect of stress on the coronary blood flow in hypertrophied heart.
Bozhko
A P
AP
Solodkov
A P
AP
D000818:Animals; D001017:Aortic Coarctation / Q000150:complications / Q000209:etiology / Q000503:physiopathology; D006332:Cardiomegaly / Q000209:etiology / Q000503:physiopathology*; D003326:Coronary Circulation / Q000187:drug effects* / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D005260:Female; D066298:In Vitro Techniques; D009200:Myocardial Contraction / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000150:complications / Q000209:etiology / Q000503:physiopathology*; D013963:Thyroid Hormones / Q000494:pharmacology*
D013963:Thyroid Hormones
Vliianie tireoidnykh gormonov na stressornye izmeneniia koronarnogo krovotoka i sokratitel'noĭ funktsii gipertrofirovannogo serdtsa.