O-Dealkylation and N4-acetylation of sulpha-2-monomethoxine by the turtle Pseudemys scripta elegans.
Sulpha-2-monomethoxine is N4-acetylated to an extent of 12% of the dose by Pseudemys scripta elegans; 48% is excreted unchanged. No O-dealkylation of the 2-methoxy group takes place.
Vree
T B
TB
Department of Clinical Pharmacy, Academic Hospital Nijmegen Sint Radboud, The Netherlands.
Vree
M L
ML
Beneken Kolmer
E W
EW
Hekster
Y A
YA
Shimoda
M
M
Ono
M
M
Miura
T
T
D000107:Acetylation; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D003640:Dealkylation; D013422:Sulfamonomethoxine / Q000493:pharmacokinetics*; D014426:Turtles / Q000378:metabolism*
D013422:Sulfamonomethoxine