Aetiological association of virus like particles with hepatitis C.
Isolation of virus-like particles from sera of anti-HCV positive patients and their ultrastructural characterization are reported. Particles were identified in sera of 5 out of 6 patients tested. Immunoelectron microscopy assay revealed small aggregates of viral particles. Size and morphological criteria suggest that these particles can be classified as Togaviridae.
Borgia
G
G
Clinica delle Malattie Infettive, II Facoltà di Medicina e Chirugia, Università di Napoli.
Cicciarello
S
S
Lambiase
A
A
Nasti
G
G
Tallarino
A
A
Reynaud
L
L
Piazza
M
M
D016174:Hepacivirus / Q000145:classification / Q000302:isolation & purification* / Q000648:ultrastructure; D006526:Hepatitis C / Q000209:etiology / Q000382:microbiology*; D006521:Hepatitis, Chronic / Q000382:microbiology; D006801:Humans; D014035:Togaviridae / Q000145:classification