title: Nasal mucociliary function: comparison of saccharin clearance with ciliary beat frequency.
abstract: Mucociliary clearance as measured by saccharin clearance time is in part dependent on the physiological characteristics of mucus and is partly dependent on ciliary function. This study compared the relationship between saccharin clearance time and ciliary beat frequency in 44 patients attending a rhinology clinic. Whilst saccharin clearance time may be used as a screening test for ciliary function there was no clear linear relationship between mucociliary clearance and ciliary beat frequency.
authors.affiliation: Dept. of O.R.L., Queen Elizabeth Hospital, Birmingham, United Kingdom.
authors.forename: B G
authors.initials: BG
authors.lastname: Moriarty
authors.forename: A M
authors.initials: AM
authors.lastname: Robson
authors.forename: L A
authors.initials: LA
authors.lastname: Smallman
authors.forename: A B
authors.initials: AB
authors.lastname: Drake-Lee
mesh_terms: D000328:Adult; D000368:Aged; D002923:Cilia / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009079:Mucociliary Clearance; D009093:Mucus / Q000502:physiology; D009297:Nasal Mucosa / Q000378:metabolism*; D012439:Saccharin / Q000493:pharmacokinetics*
chemical_list: D012439:Saccharin