Treatment of seborrhoeic dermatitis of the scalp with ketoconazole shampoo. A double-blind study.
Thirty-six patients with seborrhoeic dermatitis of the scalp and culture positive for Pityrosporum ovale were treated in a double-blind placebo controlled study with ketoconazole shampoo twice weekly for 4 weeks. In the ketoconazole group, 16 of 18 patients (89%) became free of lesions or improved, compared with only 8 of 18 (p less than 0.01) in the placebo group. The patients found the shampoo effective, easy to use and cosmetically attractive.
Faergemann
J
J
Department of Dermatology, University of Gothenburg, Sahlgrens' Hospital, Sweden.
D000328:Adult; D012628:Dermatitis, Seborrheic / Q000188:drug therapy* / Q000382:microbiology; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007654:Ketoconazole / Q000627:therapeutic use*; D008290:Malassezia / Q000302:isolation & purification; D008297:Male; D012536:Scalp Dermatoses / Q000188:drug therapy*; D012915:Soaps / Q000627:therapeutic use*; D013501:Surface-Active Agents / Q000627:therapeutic use*
D012915:Soaps; D013501:Surface-Active Agents; D007654:Ketoconazole