[Clinico-immunocytological characteristics of leukemia in persons exposed to ionizing radiation effects due to the Chernobyl AES accident].
A total of 18 patients with acute leukemia from those exposed to radiation when they had liquidated the consequences of the accident at the Chernobyl Atomic Power Station were examined. Sixteen of them had acute myeloblast cell leukemia, one had acute lymphatic leukemia, and another one had acute promyelocytic leukemia. A complex of hematological, immunocytological, and cytochemical findings, as well as leukocytic and erythrocytic genetically determined antigen typing were used for diagnosis. Signs of severe vegetovascular dystonia was found to be followed by acute leukemia in all the patients. A relationship was established between the therapy resistance and the HLA antigen homozygosity in combination with genetically-determined low reactivity. There were no significant differences between the parameters in question and those in patients with acute leukemia who had been studied in the preaccident period.
Bebeshko
V G
VG
Klimenko
V I
VI
Chumak
A A
AA
Bazyka
D A
DA
Tal'ko
V V
VV
Minchenko
Zh N
ZhN
Bruslova
E M
EM
Galkina
S G
SG
D000059:Accidents; D000328:Adult; D006651:Histocytochemistry; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000209:etiology; D015473:Leukemia, Promyelocytic, Acute / Q000209:etiology; D007953:Leukemia, Radiation-Induced / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology; D008297:Male; D009688:Nuclear Reactors; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000209:etiology; D014455:Ukraine
Kliniko-immunotsitologicheskaia kharakteristika leĭkozov u lits, podvergshikhsia vozdeĭstviiu ioniziruiushchikh izlucheniĭ v rezul'tate avarii na Chernobyl'skoĭ AES.