[Escherichia coli reactions to the action of the cationic proteins of blood leukocytes].
The antibacterial effect of cation proteins (CP) of swine leukocytes with respect to Escherichia coli strain 17 has been demonstrated in vitro. The composition and properties of these CP have been studied; as a result, a comparatively high content of basic and dicarbonic amino acids and the presence of protease activity have been established. The release of the components of the metabolic fund by E. coli under the influence of CP of swine leukocytes is indicative of changes in the permeability of microbial membranes and, probably, of the deficiency of energy resources. The addition of heparin to CP of swine leukocytes levels their antibacterial effect with respect to E. coli.
Zhdan-Pushkina
S M
SM
Rybakova
L P
LP
D000818:Animals; D001770:Blood Bactericidal Activity / Q000276:immunology; D001798:Blood Proteins / Q000032:analysis / Q000494:pharmacology*; D015169:Colony Count, Microbial; D003470:Culture Media; D004305:Dose-Response Relationship, Drug; D004926:Escherichia coli / Q000187:drug effects* / Q000254:growth & development; D007962:Leukocytes / Q000737:chemistry / Q000276:immunology*; D013552:Swine; D013997:Time Factors
D001798:Blood Proteins; D003470:Culture Media
O reaktsiiakh Escherichia coli na deĭstvie kationnykh belkov leĭkotsitov krovi.