title: Ruptured abdominal aortic aneurysms: factors affecting mortality rates.
abstract: Outcome of 113 operations for ruptured abdominal aortic aneurysms were reviewed to determine the contribution of perioperative events to mortality rates. Preoperative, intraoperative, and postoperative factors were examined with regard to their influence on early and late deaths. A mortality rate of 64% (72/113) was unrelated to age, gender, and preexistent medical conditions. Death within 48 hours occurred in 42 of 72 patients (58%). Preoperative status, including cardiac arrest, loss of consciousness, and acidosis influenced early deaths (less than 48 hours) but not late deaths. Early deaths were also influenced by severe operative hypotension and excessive transfusion requirements. Late deaths (greater than 48 hours) occurred in 30/72 cases (42%) at a mean of 24.6 +/- 22.9 days. Late death was related to postoperative organ system failure, specifically renal and respiratory failure, and the need for reoperation. The overall mortality rate was influenced by preoperative, intraoperative, and postoperative factors. Postoperative renal failure was the strongest predictor of overall deaths. Survival after ruptured abdominal aortic aneurysm depends on intraoperative and postoperative complications as well as preoperative conditions. Late death, the greatest strain on resources, is independent of preoperative status. The thesis that some patients with ruptured abdominal aortic aneurysm should be denied operation to conserve resources is not supported by these data. Efforts to improve survival should focus on reducing intraoperative complications and improving management of postoperative organ failure.
authors.affiliation: Department of Surgery, State University of New York, Buffalo.
authors.forename: L M
authors.initials: LM
authors.lastname: Harris
authors.forename: G L
authors.initials: GL
authors.lastname: Faggioli
authors.forename: R
authors.initials: R
authors.lastname: Fiedler
authors.forename: G R
authors.initials: GR
authors.lastname: Curl
authors.forename: J J
authors.initials: JJ
authors.lastname: Ricotta
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001012:Aorta, Abdominal; D001019:Aortic Rupture / Q000175:diagnosis / Q000191:economics / Q000401:mortality* / Q000601:surgery; D003951:Diagnostic Errors; D005260:Female; D015276:Health Care Rationing; D006801:Humans; D007431:Intraoperative Complications / Q000401:mortality*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011183:Postoperative Complications / Q000401:mortality*; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors