title: Isolation, structure, and synthesis of novel 4-quinolinone alkaloids from Esenbeckia leiocarpa.
abstract: Two new biocidal quinolinone alkaloids, 3-methoxy-1-methyl-2-propyl-4-quinolone [1] and 2(1'-ethylpropyl)-1-methyl-4-quinolone [2], were efficiently isolated using reversed-phase recycling hplc from the leaves of Esenbeckia leiocarpa. The structures were determined through spectroscopic data and confirmed by total synthesis. These alkaloids have antifeedant activities against the pink bollworm, Pectinophora gossypiella.
authors.affiliation: Division of Entomology and Parasitology, College of Natural Resources, Berkeley, California.
authors.forename: T
authors.initials: T
authors.lastname: Nakatsu
authors.forename: T
authors.initials: T
authors.lastname: Johns
authors.forename: I
authors.initials: I
authors.lastname: Kubo
authors.forename: K
authors.initials: K
authors.lastname: Milton
authors.forename: M
authors.initials: M
authors.lastname: Sakai
authors.forename: K
authors.initials: K
authors.lastname: Chatani
authors.forename: K
authors.initials: K
authors.lastname: Saito
authors.forename: Y
authors.initials: Y
authors.lastname: Yamagiwa
authors.forename: T
authors.initials: T
authors.lastname: Kamikawa
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification*; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D005247:Feeding Behavior / Q000187:drug effects; D007313:Insecta; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010944:Plants / Q000032:analysis*; D015363:Quinolones / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D000470:Alkaloids; D015363:Quinolones; C068517:leiokinine B; C068516:leiokinine A