title: Hexokinase and 'glucokinase' in liver metabolism.
abstract: Rat liver contains four hexokinase isoenzymes, one of which, despite often being called 'glucokinase', is no more specific for glucose than the others. However, it does differ from them in displaying a sigmoid kinetic response to glucose, requiring much higher glucose concentrations for activity, and being insensitive to physiological concentrations of glucose 6-phosphate.
authors.affiliation: Centre de Biochimie et de Biologie Moléculaire, Centre National de la Recherche Scientifique, Marseille, France.
authors.forename: A
authors.initials: A
authors.lastname: Cornish-Bowden
authors.forename: M L
authors.initials: ML
authors.lastname: Cárdenas
mesh_terms: D000818:Animals; D005941:Glucokinase / Q000378:metabolism; D006593:Hexokinase / Q000378:metabolism*; D007527:Isoenzymes / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000378:metabolism*; D051381:Rats
chemical_list: D007527:Isoenzymes; D006593:Hexokinase; D005941:Glucokinase