title: [A case report of pseudoxanthoma elasticum with upper gastrointestinal hemorrhage].
abstract: A gastric hemorrhage in a patient with pseudoxanthoma elasticum (PXE) is reported. A 44-year-old woman was admitted to our hospital with hematemesis. Bleeding point was located at upper body of the stomach. As neither endoscopic alcohol injection nor operative hemostasis by over sewing under gastrotomy were unsuccessful, total gastrectomy was performed. Histologic examination of the stomach revealed fragmentation of elastic fiber in the internal lamina of arteriole and degeneration of muscle layer. This change was observed fundamentally in all specimens obtained from different region of the stomach. In addition to describing clinical and pathological feature of this case, the management of gastric hemorrhage in patients with PXE is discussed.
authors.affiliation: Department of Traumatology, Osaka University School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Yamamura
authors.forename: A
authors.initials: A
authors.lastname: Hiraide
authors.forename: H
authors.initials: H
authors.lastname: Tabuse
authors.forename: H
authors.initials: H
authors.lastname: Yamamoto
authors.forename: H
authors.initials: H
authors.lastname: Sugimoto
authors.forename: T
authors.initials: T
authors.lastname: Yoshioka
authors.forename: T
authors.initials: T
authors.lastname: Sugimoto
mesh_terms: D000328:Adult; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000150:complications* / Q000473:pathology; D006801:Humans; D011561:Pseudoxanthoma Elasticum / Q000150:complications* / Q000473:pathology