Comparison of high and low doses of suxamethonium.
In a double-blind study, 67 young adult patients undergoing anaesthesia for dental extractions were allocated at random to receive either 0.5 mg/kg or 1.5 mg/kg suxamethonium. A greater increase in arterial pressure was seen following induction in the 1.5 mg/kg group, although overall intubating conditions were similar in the two groups. Suxamethonium-associated muscle pains were significantly more common in the group which received the larger dose (p less than 0.05).
Stewart
K G
KG
University Department of Anaesthesia, St James University Hospital, Leeds.
Hopkins
P M
PM
Dean
S G
SG
D000328:Adult; D001794:Blood Pressure / Q000187:drug effects; D004311:Double-Blind Method; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007442:Intubation, Intratracheal; D008297:Male; D009132:Muscles / Q000503:physiopathology*; D010149:Postoperative Pain / Q000209:etiology*; D013390:Succinylcholine / Q000008:administration & dosage* / Q000009:adverse effects / Q000494:pharmacology; D014081:Tooth Extraction
D013390:Succinylcholine