title: Illustration of the effects of long-term xamoterol therapy on the time course of left ventricular pressure.
abstract: Detailed left ventricular haemodynamic investigations were performed in eight patients with New York Heart Association (NYHA) Class II heart failure, eight with NYHA Class III heart failure with an ejection fraction less than 35%, and six with severe heart failure. Xamoterol (200 mg b.d. for 3 months) caused a fall in left ventricular end-diastolic pressure, an increase in dP/dTmax and a shorter systole in all groups of patients.
authors.affiliation: Division of Cardiology, University of Louvain, Brussels, Belgium.
authors.forename: H
authors.initials: H
authors.lastname: van Mechelen
authors.forename: A
authors.initials: A
authors.lastname: Ries
authors.forename: H
authors.initials: H
authors.lastname: Pouleur
authors.forename: M F
authors.initials: MF
authors.lastname: Rousseau
mesh_terms: D000318:Adrenergic beta-Agonists / Q000494:pharmacology* / Q000627:therapeutic use; D001794:Blood Pressure / Q000187:drug effects; D002303:Cardiac Output, Low / Q000188:drug therapy; D006321:Heart / Q000187:drug effects*; D006801:Humans; D009200:Myocardial Contraction / Q000187:drug effects*; D011412:Propanolamines / Q000494:pharmacology* / Q000627:therapeutic use; D017307:Xamoterol
chemical_list: D000318:Adrenergic beta-Agonists; D011412:Propanolamines; D017307:Xamoterol