[A computing laboratory-clinical system in the screening of malignant tumors: study of the state of the antioxidant system and level of cellular proliferation markers among the population from the Chernobyl AES accident area].
The author bases and describes the computing laboratory and clinical system for screening groups at a higher risk for malignant neoplasms whose incidence is likely to increase due to irradiation. Two years after the disaster the detected group at a higher risk was 2-2.4 times larger than the control group among persons who received the total irradiation dose 5 rem and over as well as among persons who are to be removed from the area polluted with radionuclides whatever the dose. As the time elapsed since the disaster increases, the number of subjects with a higher level of biomarkers also grows. It is advisable that this system be introduced in all fields of the practical health care in the polluted and control areas to carry out goal-oriented treatment and diagnostic measures in the selected population groups.
Grigorovich
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D000059:Accidents; D000975:Antioxidants; D015415:Biomarkers; D006801:Humans; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis / Q000517:prevention & control*; D009688:Nuclear Reactors; D011829:Radiation Dosage; D012307:Risk Factors; D012984:Software; D013997:Time Factors; D014455:Ukraine
D000975:Antioxidants; D015415:Biomarkers
Vychislitel'naia laboratorno-klinicheskaia sistema dlia skrininga zlokachestvennykh opukholeĭ: issledovanie sostoianiia antioksidantnoĭ sistemy i urovnia markerov kletochnoĭ proliferatsii sredi kontingentov iz zony avarii na Chernobyl'skoĭ AES.