[The mechanism of the incorporation into alpha-cells of double-stranded RNA, DNA and reconstructed nucleosomes].
It is shown that the interaction of Ca precipitate of double stranded RNA, DNA, including the reconstructed in nucleosome structures DNA with L-cells plasmatic membrane surface induced the increase of cyclic AMP content, stimulates calcium ion input as well the activity of phospholipase A2, resulting in increase of the phospholipid lysoform and unsaturated fatty acid level in membrane, providing the possibility of nucleic acid biopolymer translocation into cell.
Zakharian
R A
RA
Rukhkian
L A
LA
D000818:Animals; D002118:Calcium / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism; D000242:Cyclic AMP / Q000378:metabolism; D004247:DNA / Q000378:metabolism*; D005231:Fatty Acids, Unsaturated / Q000378:metabolism; D007739:L Cells / Q000378:metabolism*; D008563:Membrane Lipids / Q000378:metabolism; D051379:Mice; D009707:Nucleosomes / Q000378:metabolism*; D010741:Phospholipases A / Q000378:metabolism; D054467:Phospholipases A2; D010743:Phospholipids / Q000378:metabolism; D012330:RNA, Double-Stranded / Q000378:metabolism*
D005231:Fatty Acids, Unsaturated; D008563:Membrane Lipids; D009707:Nucleosomes; D010743:Phospholipids; D012330:RNA, Double-Stranded; D004247:DNA; D000242:Cyclic AMP; D010741:Phospholipases A; D054467:Phospholipases A2; D002118:Calcium
K mekhanizmu vkliucheniia v al'fa-kletki dvuspiral'noĭ RNK, DNK i rekonstruirovannykh nukleosom.