title: Does orthotopic liver transplantation heal Wilson's disease? Clinical follow-up of two liver-transplanted patients.
abstract: Two patients with Wilson's disease (WD) underwent orthotopic liver transplantation, one for subacute liver failure and the other for severe oesophageal haemorrhage. After transplantation both patients fully recovered within five months, and copper metabolism returned to normal. Follow-up examinations were continued for 4 and 6 years. Clinical as well as electrophysiological testing in these two patients yielded better results than in most of 12 WD-patients being conventionally treated for a similar period or even longer.
authors.affiliation: Department of Neurology, Heinrich-Heine University of Düsseldorf, West-Germany.
authors.forename: H
authors.initials: H
authors.lastname: Hefter
authors.forename: W
authors.initials: W
authors.lastname: Rautenberg
authors.forename: G
authors.initials: G
authors.lastname: Kreuzpaintner
authors.forename: G
authors.initials: G
authors.lastname: Arendt
authors.forename: H J
authors.initials: HJ
authors.lastname: Freund
authors.forename: R
authors.initials: R
authors.lastname: Pichlmayr
authors.forename: G
authors.initials: G
authors.lastname: Strohmeyer
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006527:Hepatolenticular Degeneration / Q000601:surgery*; D006801:Humans; D016031:Liver Transplantation