title: [Severe aplastic anemia].
abstract: Severe aplastic anemia is a rare disorder which is most often fatal when bone marrow transplantation or an immunosuppressive regimen is not applied. The cause of the disease in individual patients is not identifiable by laboratory investigations. The decision for a therapeutic modality is based on patient age and availability of an HLA-identical bone marrow donor. Early application of bone marrow transplantation may cure up to 80% of patients. Many patients may also be rescued with combined, intensive immunosuppression. Each of these treatment modalities, however, require early application, prior to the onset of typical complications such as infection and bleeding.
authors.affiliation: I. Medizinischen Universitätsklinik Wien.
authors.forename: W
authors.initials: W
authors.lastname: Hinterberger
mesh_terms: D000741:Anemia, Aplastic / Q000209:etiology / Q000628:therapy*; D016026:Bone Marrow Transplantation; D006801:Humans; D007165:Immunosuppression Therapy; D011379:Prognosis
vernacular_title: Schwere aplastische Anämie.