title: Protein phosphatase activities in vivo in Xenopus laevis oocyte: inhibition by okadaic acid.
abstract: Protein phosphatase activities were analyzed in vivo in Xenopus oocytes. The dephosphorylation of microinjected beta casein was inhibited when the tumor promoter okadaic acid was microinjected into oocytes. Inhibition was dose dependent and reversible; 50% of activity was recovered 15-30 minutes after microinjection.
authors.affiliation: Laboratoire de Physiologie de la Reproduction, UA CNRS 555, INRA, UPMC, Paris, France.
authors.forename: P
authors.initials: P
authors.lastname: Cormier
authors.forename: O
authors.initials: O
authors.lastname: Mulner-Lorillon
authors.forename: R
authors.initials: R
authors.lastname: Ozon
authors.forename: R
authors.initials: R
authors.lastname: Bellé
mesh_terms: D000818:Animals; D002364:Caseins / Q000378:metabolism; D004988:Ethers, Cyclic / Q000494:pharmacology*; D005260:Female; D007700:Kinetics; D008845:Microinjections; D019319:Okadaic Acid; D009865:Oocytes / Q000187:drug effects / Q000201:enzymology*; D010749:Phosphoprotein Phosphatases / Q000037:antagonists & inhibitors*; D010766:Phosphorylation; D011499:Protein Processing, Post-Translational; D014982:Xenopus laevis
chemical_list: D002364:Caseins; D004988:Ethers, Cyclic; D019319:Okadaic Acid; D010749:Phosphoprotein Phosphatases