title: [Etiology of deep venous thrombosis of the leg].
abstract: 50% of all patients with deep venous thrombosis (DVT) are simultaneously suffering from other diseases, which might support or cause the thrombogenesis. In the other 50% no etiological factor can be identified. There are several factors predisposing to DVT, such as immobilisation, surgery, old age of the patient, estrogen treatment. These factors are risk factors but not etiological factors. DVT is not only initiated by the three main factors (hypercoagulability, stasis, endothelial lesion) already described by Virchow. A very complicated balance of several complex single systems (endothelium, vessel wall motion, thrombocytes, hemostatic and fibrinolytic systems with their inhibitors) has to be disturbed in order to initiate venous thrombosis.
authors.affiliation: Medizinischen Universitätsklinik, Karl-Franzens-Universität Graz.
authors.forename: E
authors.initials: E
authors.lastname: Pilger
authors.forename: A
authors.initials: A
authors.lastname: Obernosterer
authors.forename: G
authors.initials: G
authors.lastname: Stark
authors.forename: M
authors.initials: M
authors.lastname: Decrinis
mesh_terms: D001779:Blood Coagulation Factors / Q000502:physiology; D001809:Blood Viscosity / Q000502:physiology; D004730:Endothelium, Vascular / Q000503:physiopathology; D005342:Fibrinolysis / Q000502:physiology; D006801:Humans; D010974:Platelet Aggregation / Q000502:physiology; D012307:Risk Factors; D013924:Thrombophlebitis / Q000097:blood / Q000209:etiology*; D014689:Venous Insufficiency / Q000097:blood / Q000150:complications
chemical_list: D001779:Blood Coagulation Factors
vernacular_title: Atiologie der tiefen Beinvenenthrombose.