Changes of neuron-specific enolase concentration in plasma after cardiac arrest and resuscitation.
The concentration of neuron-specific enolase (NSE) was measured in plasma of 18 patients after cardiac arrest and resuscitation (14 nonsurvivors and 4 survivors). In all patients, the NSE concentration was significantly higher in comparison to reference values. The highest concentration was measured in nonsurvivors. Time-course investigation in the first 24 h after cardiac arrest was performed in five patients. Two nonsurvivors and one survivor of the five patients showed a significant rise, and a NSE peak concentration of 42.7 micrograms/L, 13.6 micrograms/L, and 10.5 micrograms/L, respectively, was found 10-19 h after cardiac arrest.
Dauberschmidt
R
R
Research Department of Intensive Care Medicine, Friedrichshain Hospital, Berlin, Germany.
Zinsmeyer
J
J
Mrochen
H
H
Meyer
M
M
D002545:Brain Ischemia / Q000201:enzymology* / Q000209:etiology; D016887:Cardiopulmonary Resuscitation; D006323:Heart Arrest / Q000150:complications / Q000201:enzymology*; D006801:Humans; D010751:Phosphopyruvate Hydratase / Q000097:blood*
D010751:Phosphopyruvate Hydratase