title: [Berberine-electrochemical detector for the determination of berberine-type alkaloids in various Chinese patent medicines by flow injection analysis].
abstract: A description is given for the preparation of flow through sensor and of the incorporation of the sensor into a flow injection analysis system. The parameters affecting the measurement are discussed. An accurate, convenient and rapid method is proposed for the determination of berberine-type alkaloids in various Chinese patent medicines (Coptis chinensis Franch., Phellodendron chinesis Schneid., xianglian wan, zuojin wan, ermiao wan and sanmiao wan). The slope is 54-60 mV/decade over the concentration range of 10(-3)-3 x 10(-6) mol/L berberine at pH 2-9.5. Direct potentiometry determination of berberine in various samples showed an average recovery of 99.5-103.5% and a relative standard deviation of 1.3-3.5% at a sampling rate of 120/h.
authors.affiliation: Hubei Provincial Institute for Drug Control, Wuhan.
authors.forename: W Z
authors.initials: WZ
authors.lastname: Liu
authors.forename: W B
authors.initials: WB
authors.lastname: Peng
authors.forename: C H
authors.initials: CH
authors.lastname: Yang
mesh_terms: D001599:Berberine / Q000032:analysis*; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D011199:Potentiometry / Q000379:methods
chemical_list: D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D001599:Berberine