title: Application of preembedding immunohistochemistry in the study of adenohypophysial plurihormonality.
abstract: An immunoelectron microscopy preembedding technique has been utilized as a method which enables the observation of various bioactive substances in various intracellular organelles. In this review article, the observations made by preembedding immunoelectron microscopy describe plurihormonal pituitary cell emphasizing subcellular localization of hormones and their alterations.
authors.affiliation: Department of Pathology, Tokai University School of Medicine, Kanagawa, Japan.
authors.forename: R Y
authors.initials: RY
authors.lastname: Osamura
mesh_terms: D000818:Animals; D006801:Humans; D007150:Immunohistochemistry; D016253:Microscopy, Immunoelectron; D010903:Pituitary Gland, Anterior / Q000648:ultrastructure*; D010907:Pituitary Hormones / Q000378:metabolism*; D016610:Tissue Embedding / Q000379:methods*
chemical_list: D010907:Pituitary Hormones