title: [Primary neural leprosy. Report of a case].
abstract: We present the clinical manifestations and morphological characteristics in a case from a patient with familial history of leprosy that presented peripheral neuropathy without cutaneous lesions. The nerves affected showed a loss of myelinated and unmyelinated fibers as well as chronic inflammatory infiltrate. The presence of Hansen's bacillus was demonstrated in macrophages, Schwann cells, endothelial cells, and fibroblasts at light and ultrastructural levels. In this case, the demonstration of the bacillus in the biopsy of peripheral nerve confirmed the diagnosis.
authors.affiliation: Departamento de Patología, Hospital Clínico Universitario, Valencia.
authors.forename: A
authors.initials: A
authors.lastname: Cremades Mira
authors.forename: M
authors.initials: M
authors.lastname: Cerda Nicolás
authors.forename: A
authors.initials: A
authors.lastname: Lago
authors.forename: A
authors.initials: A
authors.lastname: Llombart Bosch
mesh_terms: D005188:False Negative Reactions; D005260:Female; D006801:Humans; D007916:Lepromin; D015441:Leprosy, Tuberculoid / Q000175:diagnosis* / Q000382:microbiology; D008875:Middle Aged; D009166:Mycobacterium leprae / Q000302:isolation & purification*; D010292:Paresthesia / Q000382:microbiology / Q000473:pathology; D011115:Polyneuropathies / Q000382:microbiology* / Q000473:pathology; D013497:Sural Nerve / Q000382:microbiology / Q000473:pathology
chemical_list: D007916:Lepromin
vernacular_title: Lepra neural primaria. A propósito de un caso.