title: Synergistic effect of prostaglandin E1 and isosorbide dinitrate in peripheral vascular disease.
abstract: Isosorbide dinitrate, which releases nitric oxide in vivo, and prostaglandin E1 synergised in reducing platelet deposition and increasing platelet survival time in patients with peripheral vascular disease.
authors.affiliation: Atherosclerosis Research Group, Vienna, Austria.
authors.forename: H
authors.initials: H
authors.lastname: Sinzinger
authors.forename: P
authors.initials: P
authors.lastname: Fitscha
authors.forename: J
authors.initials: J
authors.lastname: O'Grady
authors.forename: F
authors.initials: F
authors.lastname: Rauscha
authors.forename: W
authors.initials: W
authors.lastname: Rogatti
authors.forename: J R
authors.initials: JR
authors.lastname: Vane
mesh_terms: D000368:Aged; D001161:Arteriosclerosis / Q000097:blood* / Q000150:complications; D003327:Coronary Disease / Q000097:blood* / Q000150:complications; D004334:Drug Administration Schedule; D004341:Drug Evaluation; D004357:Drug Synergism; D005260:Female; D006801:Humans; D007548:Isosorbide Dinitrate / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology; D010976:Platelet Count / Q000187:drug effects*; D011458:Prostaglandins E / Q000008:administration & dosage / Q000494:pharmacology*; D016032:Randomized Controlled Trials as Topic
chemical_list: D010975:Platelet Aggregation Inhibitors; D011458:Prostaglandins E; D007548:Isosorbide Dinitrate