title: [A case report of early prosthetic valve endocarditis due to methicillin resistant Staphylococcus aureus infection--an experience of intraatrial implantation of mitral prosthesis with a Gore-Tex flange].
abstract: A 60-year-old female with mitral stenosis developed prosthetic valve endocarditis due to methicillin resistant staphylococcus aureus septicemia 3 weeks after mitral valve replacement. In vitro test disclosed susceptibility to minocycline and clindamycin. Despite large amount of intravenous administration, progressive heart failure due to massive perivalvular leakage occurred as a consequence of persisting infection. An emergent operation revealed valve detachment of the posterior portion resulting from ring abscess formation. A mitral prosthesis with a Gore-Tex flange was implanted partially in the left atrium just above the mitral ring and sutured to the atrial wall. Postoperative relapse was not detected even after discontinuing antibiotics. Prosthetic valve endocarditis due to methicillin resistant staphylococcus aureus is highly resistant to antibiotic therapy and likely to develop valve ring abscess. Prompt surgical treatment is mandatory in this situation.
authors.affiliation: Department of Cardiovascular Surgery, Turumai Hospital, Ichihara, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Murayama
authors.forename: Y
authors.initials: Y
authors.lastname: Takahara
authors.forename: I
authors.initials: I
authors.lastname: Nakada
authors.forename: Y
authors.initials: Y
authors.lastname: Sudo
authors.forename: T
authors.initials: T
authors.lastname: Sezaki
authors.forename: T
authors.initials: T
authors.lastname: Nakamura
mesh_terms: D004697:Endocarditis, Bacterial / Q000209:etiology / Q000601:surgery*; D005260:Female; D006325:Heart Atria / Q000601:surgery; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D016106:Methicillin Resistance; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery; D011138:Polytetrafluoroethylene; D012086:Reoperation; D013203:Staphylococcal Infections / Q000209:etiology / Q000601:surgery*; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D011138:Polytetrafluoroethylene