title: Symptoms and signs in infants younger than 6 months of age correlated with the severity of their illness.
abstract: Symptoms and signs were recorded for 1007 infants younger than 6 months of age seen at home (298) or hospital (709) and correlated with four grades of illness severity. Most symptoms, present in the preceding 3 days, were associated with all grades of illness. Only four symptoms were not reported in well infants: a fluid intake less than a third of normal, convulsions, frank blood in the stools, and bile-stained vomiting. By comparison, many signs were seen only in ill infants. Those associated only with moderate or serous illness were marked retraction of the lower ribs, high-pitched or moaning cry, expiratory grunt, loss of alertness, central cyanosis, and severe hypotonia. Although these will not identify all seriously ill infants, parents and professionals should be taught to recognize these important symptoms and signs of serious illness.
authors.affiliation: Department of Paediatrics, University of Cambridge, England.
authors.forename: C J
authors.initials: CJ
authors.lastname: Morley
authors.forename: A J
authors.initials: AJ
authors.lastname: Thornton
authors.forename: T J
authors.initials: TJ
authors.lastname: Cole
authors.forename: M A
authors.initials: MA
authors.lastname: Fowler
authors.forename: P H
authors.initials: PH
authors.lastname: Hewson
mesh_terms: D006304:Health Status; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology / Q000503:physiopathology*; D012720:Severity of Illness Index