title: Intracellular membrane fusion.
abstract: Protein trafficking and membrane assembly are accomplished in eukaryotes by the specific targeting and fusion of vesicles. In this review we describe some of the molecules implicated as components of the fusion apparatus, and evidence that suggests the same factors are recruited for a variety of intracellular fusion events.
authors.affiliation: Program in Cellular Biochemistry and Biophysics, Rockefeller Research Laboratory, Sloan-Kettering Institute, New York, NY 10021.
authors.forename: D W
authors.initials: DW
authors.lastname: Wilson
authors.forename: S W
authors.initials: SW
authors.lastname: Whiteheart
authors.forename: L
authors.initials: L
authors.lastname: Orci
authors.forename: J E
authors.initials: JE
authors.lastname: Rothman
mesh_terms: D002352:Carrier Proteins / Q000378:metabolism; D005057:Eukaryotic Cells; D007425:Intracellular Membranes / Q000378:metabolism*; D008561:Membrane Fusion; D052066:N-Ethylmaleimide-Sensitive Proteins; D011499:Protein Processing, Post-Translational; D033921:Vesicular Transport Proteins
chemical_list: D002352:Carrier Proteins; D033921:Vesicular Transport Proteins; D052066:N-Ethylmaleimide-Sensitive Proteins