Clinical analyses and short-term prognoses of neonates with subependymal cysts.
Twenty-one neonates with subependymal cysts detected by neurosonography soon after birth were prospectively examined. The clinical and cranial sonographic findings were evaluated with respect to short-term prognosis. The prognosis was poor in 6 patients with congenital viral infection (4 with cytomegalovirus infection and 2 with rubella infection). Five patients also had neurodevelopmental abnormalities (2 with neonatal epileptic seizures, 2 with chromosomal abnormalities, and 1 with lissencephaly). The remaining 10 patients had normal psychomotor development. The incidence of congenital viral infection was statistically correlated with a poor neurodevelopmental outcome. A correlation did not exist between the short-term prognosis and each of the other clinical factors or cranial sonographic findings. Our evidence suggests that further investigation of possible subependymal cyst etiologies is required during a careful, long-term follow-up period.
Yamashita
Y
Y
Department of Pediatrics and Child Health, Kurume University School of Medicine, Japan.
Outani
Y
Y
Kawano
Y
Y
Horikawa
M
M
Matsuishi
T
T
Hashimoto
T
T
D001927:Brain Diseases / Q000151:congenital* / Q000000981:diagnostic imaging; D003560:Cysts / Q000151:congenital* / Q000000981:diagnostic imaging; D003586:Cytomegalovirus Infections / Q000151:congenital* / Q000000981:diagnostic imaging; D004453:Echoencephalography; D004805:Ependyma / Q000002:abnormalities* / Q000000981:diagnostic imaging; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000000981:diagnostic imaging*; D008297:Male; D012307:Risk Factors; D012410:Rubella Syndrome, Congenital / Q000000981:diagnostic imaging*