Virucidal activity of disinfectants: studies with the poliovirus.
The activity of various disinfectants against poliovirus (Sabin 1 an) was assessed using surface and suspension tests. The surface test showed that 2% glutaraldehyde and high concentrations of hypochlorites (9200 ppm avCl2) were effective (i.e. greater than or equal to 4 log10 reduction) against a dried virus suspension in 1 min. Diluted aldehydes ('Sporicidin' and 'Gigasept'), lower hypochlorite concentrations (1000 ppm avCl2) and peroxides (3%) were less effective while 70% ethanol showed variable results; 70% isopropanol was ineffective in 10 min. In the suspension tests hydrogen peroxide (3% and 6%) and 70% ethanol were ineffective in 1 min.
Tyler
R
R
Department of Medical Microbiology, Birmingham Medical School.
Ayliffe
G A
GA
Bradley
C
C
D004202:Disinfectants / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D017955:Poliovirus / Q000187:drug effects* / Q000254:growth & development
D004202:Disinfectants