Frequency of cytologic features in fine needle aspirates from histologically and cytologically diagnosed fibroadenomas.
Identification of key cytologic criteria for various lesions by means of stepwise logistic regression is common today and is often claimed to facilitate cytologic diagnosis. As can be expected, there usually is good agreement between the selected criteria and those given in the cytologic literature. In a study by Bottles et al based on 64 fibroadenomas, stroma, antler horn clusters and honeycomb sheets differentiated fibroadenoma from ductal carcinoma. We applied Bottles's criteria to our fibroadenoma material in order to test their value in clinical cytologic practice. In fine needle aspirates from histologically (cytologically) diagnosed fibroadenomas, stroma was found in 41 (57%), antler horn clusters in 59 (90%) and honeycomb sheets in 62 (81%), which reduced the clinical value of the criteria.
Dejmek
A
A
Department of Clinical Pathology and Cytology, Malmö General Hospital, Sweden.
Lindholm
K
K
D000232:Adenofibroma / Q000473:pathology* / Q000648:ultrastructure; D000293:Adolescent; D000328:Adult; D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D008875:Middle Aged; D012680:Sensitivity and Specificity