[Use of DNA polymorphism in forensic paternity evaluation].
Problematical paternity cases were additionally subjected to DNA-polymorphism analysis. 5 cases are reported, focusing on problems due to, 'silent' allele transmittance, relatively low probability for paternity, obvious occurrence of the extremely rare Rh gene complex CWc, involvement of brothers as putative fathers, non-paternity of a man although his W-value was 99.975%. The aim of this paper is to demonstrate the need for DNA-polymorphism analysis, if conventional blood group tests do not lead to a clear-cut decision. Extended typing of conventional blood group polymorphisms (except HLA) cannot compete with highly polymorphic DNA loci.
Henke
L
L
Laboratorium für forensische Blutgruppenkunde, Düsseldorf, Bundesrepublik Deutschland.
Paas
H
H
Hoffmann
K
K
Henke
J
J
D000328:Adult; D001789:Blood Group Antigens / Q000235:genetics*; D002648:Child; D002874:Chromosome Mapping; D004247:DNA / Q000235:genetics*; D015342:DNA Probes; D005260:Female; D005787:Gene Frequency / Q000235:genetics; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D008297:Male; D010334:Paternity; D010641:Phenotype; D011110:Polymorphism, Genetic / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length; D012204:Rh-Hr Blood-Group System / Q000235:genetics
D001789:Blood Group Antigens; D015342:DNA Probes; D006680:HLA Antigens; D012204:Rh-Hr Blood-Group System; D004247:DNA
Zum Einsatz von DNA-Polymorphismen in der Abstammungsbegutachtung.