Sticky molecules in not-so-sticky cells.
The assignment of specific roles to cell-surface proteins by standard methods can be a major problem. In the technique described below, Schneider-2 (S2) cells, an established Drosophila cell line, have been used in cell transfection and aggregation experiments. As such, they have proved to be a useful tool for the functional characterization of putative cell-adhesion molecules.
Hortsch
M
M
Department of Anatomy and Cell Biology, University of Michigan, Ann Arbor 48109-0616.
Bieber
A J
AJ
D000818:Animals; D015815:Cell Adhesion Molecules / Q000235:genetics / Q000502:physiology*; D002460:Cell Line; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics; D004331:Drosophila melanogaster
D015815:Cell Adhesion Molecules; D004247:DNA