[Postnatal weight loss in ventilated premature infants below 1500 g: significance of renal and extra-renal fluid loss].
In 9 ventilated preterm infants (birth weight 810-1310 g, gestational age 26-30 weeks) we measured total body water (D2O dilution), extracellular volume (sucrose dilution) and renal function parameters at birth and when postnatal weight loss exceeded 5% of birth weight together with day to day changes of weight, fluid balance, and serum electrolytes. A significant postnatal weight loss (-89 +/- 47 g) occurred together with a reduction of total body water (-102 +/- 95 ml) and extracellular volume (-98 +/- 59 ml) in the first three days of life. The intracellular volume did not change. At the same time fluid balance was negative due to a high extrarenal water loss on day 1 and an increasing diuresis on the following days. The serum sodium concentration remained unchanged during postnatal water loss, because the negative fluid balance was accompanied by a negative sodium balance.
Bauer
K
K
Neonatologie, Frauenklinik Grosshadern, Ludwig-Maximilians-Universität, München.
Götz
M
M
Roithmaier
A
A
Prölss
A
A
Bovermann
G
G
Versmold
H
H
D001724:Birth Weight / Q000502:physiology*; D004231:Diuresis / Q000502:physiology; D005110:Extracellular Space / Q000502:physiology; D005919:Glomerular Filtration Rate / Q000502:physiology; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000503:physiopathology*; D007424:Intracellular Fluid / Q000502:physiology; D007668:Kidney / Q000503:physiopathology; D012121:Respiration, Artificial; D012127:Respiratory Distress Syndrome, Newborn / Q000503:physiopathology; D012964:Sodium / Q000097:blood; D014882:Water-Electrolyte Balance / Q000502:physiology*; D015431:Weight Loss / Q000502:physiology*
D012964:Sodium
Postnatale Gewichtsabnahme beatmeter Frühgeborener unter 1500 g: Bedeutung des renalen und extrarenalen Flüssigkeitsverlusts.