title: Estimates of genetic and environmental components of serum isocitrate dehydrogenase (ICDH) in normal twins.
abstract: Environmental (b2) and genetic heritability (h2) of serum isocitrate dehydrogenase (ICDH) were estimated in 96 pairs of healthy twins according to a path analysis model. The results showed significant heritability (0.42) and a very low environmental component (based on obesity and level of habitual physical activity), suggesting that these factors do not influence ICDH serum activity.
authors.affiliation: Department of Biology, University of Sao Paulo, Brazil.
authors.forename: D
authors.initials: D
authors.lastname: Rapaport
authors.forename: G M
authors.initials: GM
authors.lastname: Colletto
authors.forename: M
authors.initials: M
authors.lastname: Vainzof
authors.forename: M
authors.initials: M
authors.lastname: Zatz
mesh_terms: D000328:Adult; D003402:Creatine Kinase / Q000097:blood / Q000235:genetics; D004777:Environment; D005260:Female; D006801:Humans; D007521:Isocitrate Dehydrogenase / Q000097:blood / Q000235:genetics*; D008297:Male; D008957:Models, Genetic; D011770:Pyruvate Kinase / Q000097:blood / Q000235:genetics; D014427:Twins / Q000235:genetics*; D014429:Twins, Dizygotic / Q000235:genetics; D014430:Twins, Monozygotic / Q000235:genetics
chemical_list: D007521:Isocitrate Dehydrogenase; D011770:Pyruvate Kinase; D003402:Creatine Kinase