title: [Geographic approach to the epidemiology of chloroquine-resistance of Plasmodium falciparum in tropical Africa].
abstract: Plasmodium falciparum chloroquine-resistance occurred initially in 1978 in East Africa. Its step by step propagation towards West Africa is due to several factors which coincide with a high increase of population migration and urbanization since the seventies. Several maps show the dynamics of chloroquine-resistance in Africa during that era.
authors.affiliation: Hôpital Bichat-Claude Bernard, Paris, France.
authors.forename: G
authors.initials: G
authors.lastname: Charmot
authors.forename: J M
authors.initials: JM
authors.lastname: Amat-Roze
authors.forename: F
authors.initials: F
authors.lastname: Rodhain
authors.forename: J
authors.initials: J
authors.lastname: Le Bras
authors.forename: J P
authors.initials: JP
authors.lastname: Coulaud
mesh_terms: D000349:Africa; D000818:Animals; D002738:Chloroquine / Q000494:pharmacology; D004351:Drug Resistance; D004641:Emigration and Immigration; D006801:Humans; D010963:Plasmodium falciparum / Q000187:drug effects*; D011157:Population Dynamics; D014507:Urbanization
chemical_list: D002738:Chloroquine
vernacular_title: Abord géographique de l'épidémiologie de la chloroquino-résistance de Plasmodium falciparum en Afrique tropicale.