Use of Chlamydiazyme on urine sediment for diagnosis of Chlamydia trachomatis genital infections.
The enzyme-linked immunosorbent assay testing of urine sediment in males has been FDA approved for the detection of Chlamydia trachomatis. We compared urine sediment testing to urethral or cervical swabs in 47 men and 219 women using a simpler technique than that recommended by the manufacturer. Sensitivity and specificity values of 88% and 97% for men and 29% and 98% for women, respectively, were found. Urine sediment testing is inadequate in women. However, urine sediment testing in men using our modified technique offers a rapid, accurate, and non-invasive approach which can effectively replace the use of urethral swabs throughout the military.
Boyd
R S
RS
Air Force Office of Medical Support, Brooks AFB, TX 78235.
DeMaio
J
J
D002584:Cervix Uteri / Q000382:microbiology; D002690:Chlamydia Infections / Q000175:diagnosis* / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000302:isolation & purification*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods*; D005260:Female; D005831:Genital Diseases, Female / Q000175:diagnosis* / Q000382:microbiology; D005832:Genital Diseases, Male / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D008297:Male; D012680:Sensitivity and Specificity; D014521:Urethra / Q000382:microbiology; D014556:Urine / Q000382:microbiology*