Comparison of narrow-band UV-B phototherapy and PUVA photochemotherapy in the treatment of psoriasis.
The therapeutic effectiveness of a new fluorescent lamp, Philips TL-01, which emits a narrow peak around 311-312 nm, was compared with the currently used PUVA photochemotherapy consisting of oral 8-MOP followed 2 h later by UV-A from fluorescent lamps Philips TL-09. Comparisons of therapeutic efficacy were performed in 10 patients with widespread, symmetrically distributed psoriasis lesions. They received treatment with PUVA on one half of the body and with TL-01 light on the other half; both treatments were given twice a week. It is concluded that on the average phototherapy with narrow-band UV-B is an effective as PUVA; it is certainly more convenient and probably less carcinogenic.
Van Weelden
H
H
Institute of Dermatology, State University of Utrecht, The Netherlands.
Baart de la Faille
H
H
Young
E
E
van der Leun
J C
JC
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011701:PUVA Therapy / Q000379:methods; D011565:Psoriasis / Q000188:drug therapy* / Q000532:radiotherapy; D014467:Ultraviolet Therapy