title: Evaluation of plate luting, using an in vivo ovine osteotomy model.
abstract: Bilateral, midshaft metacarpal osteotomies were performed in 11 sheep and bilateral, midshaft radial osteotomies were performed in 7 sheep. The lesions were repaired with bone plates. One of each pair of plates was luted with polymethylmethacrylate and all screws were tightened uniformly with a torque screwdriver. Sheep were allowed unrestricted exercise after surgery. At 8 weeks, 10 of 11 sheep with metacarpal osteotomies were sound and both osteotomies were healing. Seven were lame on the limb with the unluted plate during the first 3 weeks; 4 were never lame on either limb. The screws of the unluted plates were significantly (P less than 0.01) looser at 8 weeks than those in the luted plates. All of the sheep with radial osteotomies were lame in the limb with the unluted plate. Four of 7 sheep had overt loosening of the unluted plates. One sheep only had mild screw loosening with continued alignment of the osteotomy. Two of 7 sheep fractured the radius with the luted plate; these 2 sheep were lame in the limb with the unluted plate and were using the limb with the luted plate vigorously. Excluding the 2 sheep with fractures, all had substantially more screw loosening in the unluted plate. Histologically, there were no discernible differences in the vascularity or porosity of the bone under the luted vs the unluted plates. The only adverse consequence of the luting technique was introduction of a small amount of polymethylmethacrylate into the osteotomy gap in 5 bones.
authors.affiliation: Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, New Bolton Center, Kennett Square 19348.
authors.forename: D W
authors.initials: DW
authors.lastname: Richardson
authors.forename: D M
authors.initials: DM
authors.lastname: Nunamaker
mesh_terms: D000818:Animals; D001860:Bone Plates / Q000662:veterinary*; D001863:Bone Screws / Q000662:veterinary; D005260:Female; D008297:Male; D008663:Metacarpus / Q000601:surgery*; D008768:Methylmethacrylates; D010027:Osteotomy / Q000662:veterinary*; D011884:Radius / Q000601:surgery*; D012756:Sheep / Q000601:surgery*
chemical_list: D008768:Methylmethacrylates