Preliminary report: follow-up after dynamic cardiomyoplasty.
Five patients were studied 5-13 months after dynamic cardiomyoplasty for refractory heart failure. In two, muscle flap stimulation caused a pronounced increase in cardiac index (mean 55%) and ejection fraction (mean 75%); no patient showed improvement in cardiac filling pressure. 2 years after surgery, one of the patients with haemodynamic improvement died from ventricular fibrillation, and histochemistry of the stimulated muscle flap revealed predominantly fatigue-resistant type I fibres, without evidence of fibrosis. In selected cases, dynamic cardiomyopathy could be of long-term benefit.
Hagege
A A
AA
Department of Cardiology, Boucicaut Hospital, Paris, France.
Desnos
M
M
Chachques
J C
JC
Carpentier
A
A
Fernandez
F
F
Fontaliran
F
F
Guerot
C
C
D000328:Adult; D002302:Cardiac Output; D002304:Cardiac Pacing, Artificial; D004452:Echocardiography; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000401:mortality / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013318:Stroke Volume; D013524:Surgical Flaps