title: Branchial arch anomalies in trisomy 18.
abstract: The authors report two newborns and one fetus with trisomy 18, who have severe anomalies of the first branchial arch: extreme microtia with imperforate external meatus in two cases, and hemifacial microsomia in a third one. Those cases point to the huge phenotypic variability of the trisomy 18.
authors.affiliation: Centre for Human Genetics, CHU Sart Tilman, Liégen, Belgium.
authors.forename: A
authors.initials: A
authors.lastname: Verloes
authors.forename: N
authors.initials: N
authors.lastname: Seret
authors.forename: V
authors.initials: V
authors.lastname: Bernier
authors.forename: M
authors.initials: M
authors.lastname: Gonzales
authors.forename: C
authors.initials: C
authors.lastname: Herens
authors.forename: L
authors.initials: L
authors.lastname: Koulischer
mesh_terms: D000015:Abnormalities, Multiple / Q000235:genetics*; D001934:Branchial Region / Q000002:abnormalities*; D002869:Chromosome Aberrations / Q000235:genetics* / Q000473:pathology; D025063:Chromosome Disorders; D002887:Chromosomes, Human, Pair 18; D004431:Ear, External / Q000002:abnormalities; D005260:Female; D005313:Fetal Death / Q000235:genetics; D006257:Head / Q000002:abnormalities; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010641:Phenotype; D014314:Trisomy