A cutaneous B-cell lymphoma of novel immunophenotype.
A case of low-grade B-cell malignant lymphoma with a prolonged restriction to the skin is described. A rearrangement of the immunoglobulin heavy-chain gene was detected using molecular techniques. The histology showed many similarities to primary mucosal lymphomas and this may represent a skin counterpart of these tumours.
Mayou
S C
SC
Department of Dermatology, St Bartholomew's Hospital, London, U.K.
Cotter
F E
FE
Norton
A J
AJ
Davies
C L
CL
Munro
D D
DD
D000328:Adult; D015139:Blotting, Southern; D002699:Chlorambucil / Q000627:therapeutic use; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D008214:Lymphocytes / Q000473:pathology; D016393:Lymphoma, B-Cell / Q000188:drug therapy / Q000235:genetics / Q000276:immunology* / Q000473:pathology; D012878:Skin Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000276:immunology* / Q000473:pathology
D002699:Chlorambucil