title: [Lipofuscin accumulation in the placenta in normal and gestosis-complicated pregnancy].
abstract: Fluorescent microscopic examination of 20 placental samples from women in whom pregnancy ran a normal course and from those who suffered from gestosis was carried out to study lipofuscin accumulation in the placenta. Lipofuscin accumulation in the placenta was found to be a normal process, reflecting activation of lipid peroxidation. Placental lipofuscin accumulation was found higher in gestosis, this pointing to a reduction of the functional potentialities of the placenta. The maximum lipofuscin levels were detected in cases with gestosis associated with threatened abortion. Further investigation of this problem is necessary.
authors.forename: O I
authors.initials: OI
authors.lastname: Volkova
authors.forename: I S
authors.initials: IS
authors.lastname: Sidorova
mesh_terms: D005260:Female; D006801:Humans; D015227:Lipid Peroxidation / Q000502:physiology*; D008062:Lipofuscin / Q000378:metabolism*; D010920:Placenta / Q000378:metabolism*; D011225:Pre-Eclampsia / Q000378:metabolism*; D011247:Pregnancy / Q000378:metabolism*
chemical_list: D008062:Lipofuscin
vernacular_title: Osobennosti nakopleniia v platsente lipofustsina pri normal'no protekaiushcheĭ i oslozhnennoĭ gestozom beremennosti.