title: Hemodynamics of revascularization of the corpora cavernosa in an animal model. A preliminary report.
abstract: Numerous revascularization procedures are used for the treatment of vasculogenic impotence. In an animal model we created three different types of bypasses: inferior epigastric artery to dorsal penile artery, to dorsal artery and to dorsal vein (anastomotic arteriovenous fistula), and to dorsal vein alone. Epigastro-dorsal anastomoses remained fully patent without anticoagulants in 3 of 4 animals. With erection the flow in the inferior epigastric artery and the retrograde flow in the dorsal artery (towards the cavernous artery) increased significantly. In the 4 studies incorporating an anastomotic arteriovenous fistula we could not establish a clear reason to incorporate the artery; runoff was demonstrated only to the venous system. Arterial bypass to the dorsal vein with a simulated emissary vein increased outflow resistance as well as improved intracorporeal pressure during erection of the corpora in 4 animals. As resting pressure was also elevated, the penile smooth muscle might be at risk for further degeneration with this procedure.
authors.affiliation: Department of Urology, University of California, San Francisco.
authors.forename: A
authors.initials: A
authors.lastname: Floth
authors.forename: J S
authors.initials: JS
authors.lastname: Paick
authors.forename: J K
authors.initials: JK
authors.lastname: Suh
authors.forename: T F
authors.initials: TF
authors.lastname: Lue
mesh_terms: D000818:Animals; D001166:Arteriovenous Shunt, Surgical / Q000379:methods; D004285:Dogs; D007172:Erectile Dysfunction / Q000209:etiology / Q000601:surgery*; D008297:Male; D010410:Penile Erection / Q000502:physiology; D010413:Penis / Q000098:blood supply*; D012039:Regional Blood Flow / Q000502:physiology; D014656:Vascular Surgical Procedures / Q000379:methods