Estimates of genetic and environmental components of serum isocitrate dehydrogenase (ICDH) in normal twins.
Environmental (b2) and genetic heritability (h2) of serum isocitrate dehydrogenase (ICDH) were estimated in 96 pairs of healthy twins according to a path analysis model. The results showed significant heritability (0.42) and a very low environmental component (based on obesity and level of habitual physical activity), suggesting that these factors do not influence ICDH serum activity.
Rapaport
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Department of Biology, University of Sao Paulo, Brazil.
Colletto
G M
GM
Vainzof
M
M
Zatz
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M
D000328:Adult; D003402:Creatine Kinase / Q000097:blood / Q000235:genetics; D004777:Environment; D005260:Female; D006801:Humans; D007521:Isocitrate Dehydrogenase / Q000097:blood / Q000235:genetics*; D008297:Male; D008957:Models, Genetic; D011770:Pyruvate Kinase / Q000097:blood / Q000235:genetics; D014427:Twins / Q000235:genetics*; D014429:Twins, Dizygotic / Q000235:genetics; D014430:Twins, Monozygotic / Q000235:genetics
D007521:Isocitrate Dehydrogenase; D011770:Pyruvate Kinase; D003402:Creatine Kinase