title: [Nimodipine in subarachnoid hemorrhage].
abstract: The efficacy of nimodipine in decreasing mortality and morbidity of subarachnoid haemorrhage (HSA) is evaluated in 51 patients admitted to the Neurological and Neurosurgery Departments of the Santa Maria Hospital. Reductions of 2 x (0.65, 6.39) of the incidence of ischemia in the total group and of 2.1 x (0.58, 7.79) of mortality in the sub-group with initial severity of less than 4 points of the Hunt score were observed relatively to a comparable group of patients previously admitted who did not receive nimodipine. Randomized clinical trials that tested the effect of nimodipine in the context of HSA are reviewed.
authors.affiliation: Serviço de Neurologia, Hospital de Santa Maria, Lisboa.
authors.forename: J M
authors.initials: JM
authors.lastname: Ferro
authors.forename: P
authors.initials: P
authors.lastname: Canhão
authors.forename: T P
authors.initials: TP
authors.lastname: Melo
authors.forename: J G
authors.initials: JG
authors.lastname: Campos
authors.forename: A
authors.initials: A
authors.lastname: Trindade
authors.forename: J L
authors.initials: JL
authors.lastname: Antunes
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009553:Nimodipine / Q000627:therapeutic use*; D016017:Odds Ratio; D013345:Subarachnoid Hemorrhage / Q000188:drug therapy*
chemical_list: D009553:Nimodipine
vernacular_title: Nimodipina na hemorragia subaracnoideia.