title: A vascular effect of IgG therapy may prevent transplacental red cell leakage and spontaneous thrombocytopenic haemorrhages.
abstract: It is postulated that intravenous immunoglobin therapy may improve the red cell barrier of placenta and of capillary endothelia; the former protecting against anti-Rh antibody booster reaction and the latter preventing spontaneous thrombocytopenic bleedings. The effect on permeability may also reduce the passage of anti-Rh antibodies to the foetus.
authors.affiliation: Fundaciòn Hematològica, Mar del Plata, Argentina.
authors.forename: E
authors.initials: E
authors.lastname: Rewald
mesh_terms: D002199:Capillary Permeability; D004912:Erythrocytes; D005260:Female; D006470:Hemorrhage / Q000517:prevention & control*; D006801:Humans; D007074:Immunoglobulin G / Q000008:administration & dosage*; D007136:Immunoglobulins / Q000008:administration & dosage; D008875:Middle Aged; D010920:Placenta / Q000098:blood supply*; D011247:Pregnancy; D018029:Rho(D) Immune Globulin; D013921:Thrombocytopenia / Q000628:therapy
chemical_list: D007074:Immunoglobulin G; D007136:Immunoglobulins; D018029:Rho(D) Immune Globulin