title: The changes in CiNa of sheep cardiac Purkinje fibres in hyperosmotic solutions.
abstract: 1. The changes in intracellular sodium ion concentration (CiNa) of sheep cardiac Purkinje fibres in hyperosmotic solutions were studied using Na-sensitive liquid ion-exchanger microelectrodes. 2. CiNa was increased in hyperosmotic solutions containing different concentrations of sucrose from 0 to 300 mM. 3. The changes in resting membrane potential (RMP) in hyperosmotic solutions had no regularity. In most of the experiments there was hyperpolarization of the membrane but in a few cases a depolarization or no change of RMP were also observed. 4. The N-shape of I-V relations of the fibres became more pronounced in hyperosomotic solutions.
authors.affiliation: Institute für Zellphysiologie, Ruhr-Universität Bochum, FRG.
authors.forename: M A
authors.initials: MA
authors.lastname: Suleymanian
authors.forename: S N
authors.initials: SN
authors.lastname: Ayrapetyan
mesh_terms: D000818:Animals; D006329:Heart Conduction System / Q000378:metabolism*; D066298:In Vitro Techniques; D008564:Membrane Potentials / Q000502:physiology; D009994:Osmolar Concentration; D011690:Purkinje Fibers / Q000378:metabolism* / Q000502:physiology; D012756:Sheep / Q000378:metabolism*; D012964:Sodium / Q000378:metabolism*
chemical_list: D012964:Sodium