Controlled preparation of the endometrium with exogenous steroids for the transfer of frozen-thawed pre-embryos in patients with anovulatory or irregular cycles.
We have reported a 36% pregnancy rate (eight of 22 transfers) with the transfer of cryopreserved-thawed embryos in patients with anovulatory or irregular cycles following a protocol using pituitary suppression with leuprolide acetate after preparation of the endometrium with transdermal E2 and i.m. P. This protocol is simple, easy to follow, and safe and could be used in future for all patients with cryopreserved pre-embryos.
Muasher
S J
SJ
Howard and Georgeanna Jones Institute for Reproductive Medicine, Department of Obstetrics and Gynecology, Eastern Virginia Medical School, Norfolk 23507.
Kruithoff
C
C
Simonetti
S
S
Oehninger
S
S
Acosta
A A
AA
Jones
G S
GS
D000328:Adult; D000858:Anovulation / Q000188:drug therapy*; D015925:Cryopreservation; D004624:Embryo Transfer / Q000379:methods*; D004717:Endometrium / Q000187:drug effects*; D004958:Estradiol / Q000097:blood / Q000627:therapeutic use*; D005260:Female; D006358:Hot Temperature; D006801:Humans; D016729:Leuprolide / Q000627:therapeutic use; D008599:Menstruation Disturbances / Q000188:drug therapy*; D011374:Progesterone / Q000097:blood / Q000627:therapeutic use*
D011374:Progesterone; D004958:Estradiol; D016729:Leuprolide