[Antimicrobial activity of ceftazidime and its pharmacokinetics in patients with renal failure].
High antimicrobial activity of ceftazidime against clinical gram-positive (except Streptococcus viridans and S. faecalis) and gram-negative strains of microorganisms was shown. It was found that the drug dosing regimens required correction in cases with impaired excretion function of the kidneys. Hemodialysis lowered 2-4 times the drug blood levels.
Skala
L Z
LZ
Nasonov
V N
VN
Cherniakov
V L
VL
Nekhorosheva
A G
AG
Prokhorova
V A
VA
D002442:Ceftazidime / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D006801:Humans; D007676:Kidney Failure, Chronic / Q000188:drug therapy* / Q000378:metabolism; D006435:Renal Dialysis / Q000009:adverse effects
D002442:Ceftazidime
Antimikrobnaia aktivnost' tseftazidima i ego farmakokinetika u bol'nykh s pochechnoĭ nedostatochnost'iu.