title: The clinical management of spasticity.
abstract: Spasticity remains a common and challenging problem for patient and practitioner. Understanding of the complex pathophysiology of this disorder, despite recent advances, remains incomplete. Although newer pharmacologic agents and recently introduced technologic procedures have benefited many patients with spasticity, truly safe and effective therapeutic regimens remain elusive. A balanced approach to the problem, utilizing appropriate medication in conjunction with surgical therapy for refractory cases, is warranted. Adjunctive measures, orthopedic intervention and physical therapy modalities, often combined in a multi-disciplinary setting, offer substantial opportunity for a favorable outcome.
authors.affiliation: Indiana University School of Medicine, Indianapolis.
authors.forename: R J
authors.initials: RJ
authors.lastname: Alonso
authors.forename: E L
authors.initials: EL
authors.lastname: Mancall
mesh_terms: D006801:Humans; D009128:Muscle Spasticity / Q000503:physiopathology / Q000628:therapy*