Criteria for diagnosis of Behçet's disease. International Study Group for Behçet's Disease.
5 sets of criteria for diagnosis of Behçet's disease are in use--a problem which has hindered interpretation of different studies and collaborative research. An international study group, which included at least one proponent of 4 of the sets, was formed to derive new, internationally agreed diagnostic criteria for Behçet's disease. Data on 914 patients with Behçet's disease, from 12 centres in 7 countries, were compared with controls from the same centres. The new set of diagnostic criteria--which requires the presence of oral ulceration plus any two of genital ulceration, typical defined eye lesions, typical defined skin lesions, or a positive pathergy test--was simpler to use and had an improved discriminatory performance than its predecessors.
D000465:Algorithms; D001528:Behcet Syndrome / Q000150:complications / Q000175:diagnosis*; D005128:Eye Diseases / Q000209:etiology; D005260:Female; D005831:Genital Diseases, Female / Q000209:etiology; D005832:Genital Diseases, Male / Q000209:etiology; D006801:Humans; D008297:Male; D015337:Multicenter Studies as Topic; D011237:Predictive Value of Tests; D012008:Recurrence; D012015:Reference Standards; D012494:Sampling Studies; D012882:Skin Tests; D012883:Skin Ulcer / Q000209:etiology; D013281:Stomatitis, Aphthous / Q000209:etiology; D014456:Ulcer / Q000209:etiology