[Chemical studies of Salvia miltiorrhiza f. alba].
Fourteen constituents were isolated from the roots of Salvia miltiorrhiza f. alba. Two of them were new compounds and were named 1,2,15,16-tetrahydrotanshiquinone (I) and tanshinaldehyde (II). The others were identified as Ro-090680 (III), dihydroisotanshone I (IV), danshexinkun B (V), miltirone (VI), nortanshinone (VII), hydroxytanshinone II-A (VIII), tanshinone I (IX), dihydrotanshinone I (X), tanshinone II-A (XI), cryptotanshinone (XII), methylenetanshiquinone (XIII), methyltanshinonate (XIV), I and III showed inhibitory activity against P388 Leukemia cell in vitro. III was reported to be a potent inhibitor of rabbit platelet aggregation induced by collagen.
Li
Z T
ZT
Department of Pharmacy, Zhejiang Medical University, Hangzhou.
Yang
B J
BJ
Ma
G E
GE
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000494:pharmacology; D007941:Leukemia P388 / Q000473:pathology; D051379:Mice; D010618:Phenanthrolines / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured / Q000187:drug effects
D004365:Drugs, Chinese Herbal; D010618:Phenanthrolines; C071589:1,2,15,16-tetrahydrotanshiquinone; C071590:tanshinaldehyde