title: Complete amino acid sequence of equine miniplasminogen.
abstract: The complete amino acid sequence of equine miniplasminogen (Mr 37,132, 338 residues) was determined with the aid of fragments obtained by cleavage with 2-(2-nitrophenylsulfenyl)-3-methyl-3'-bromoindolenine, cyanogen bromide or clostripain. The fragments were aligned with overlapping sequences. Sequence comparison with other species gave identities in the range of 76% (bovine) and 81% (canine), indicating the presence of the same structural and functional domains as in the other species. Sequence comparison of different miniplasminogens showed that positions 49 (Arg), 83 (Arg) and 161 (Ser) may play a role in the interaction between plasminogen and streptokinase.
authors.affiliation: Institut für Biochemie der Universität, Bern, Switzerland.
authors.forename: J
authors.initials: J
authors.lastname: Schaller
authors.forename: C
authors.initials: C
authors.lastname: Straub
authors.forename: U
authors.initials: U
authors.lastname: Kämpfer
authors.forename: E E
authors.initials: EE
authors.lastname: Rickli
mesh_terms: D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D006736:Horses; D006801:Humans; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000737:chemistry*; D010958:Plasminogen / Q000737:chemistry*; D012689:Sequence Homology, Nucleic Acid; D012862:Skatole / Q000031:analogs & derivatives
chemical_list: D000596:Amino Acids; D010446:Peptide Fragments; C044190:miniplasminogen; C005904:BNPS-skatole; D010958:Plasminogen; D012862:Skatole