title: [Change in the passive influx of Ca2+ into sarcoplasmic reticulum vesicles as a result of chemical modification of surface amino groups].
abstract: Treatment of sarcoplasmic reticulum (SR) vesicles with trinitrobenzene (TNBS) and 1-ethyl-3(3-dimethylaminopropyl)carbodiimide (EDC) stimulates the initial rate of passive influx of Ca2+ into SR vesicles, but does not affect either the binding or the maximal passive loading of SR vesicles with Ca2+. The changes in the kinetics of KCl-stimulated passive influx of Ca2+ depend on the reagent used. It is supposed that stimulation of passive influx of Ca2+ into SR vesicles and the changes in the reaction kinetics may be caused by modification of the Ca2+ channel gating behaviour as a result of binding of surface amino groups.
authors.forename: G P
authors.initials: GP
authors.lastname: Diadiusha
authors.forename: V A
authors.initials: VA
authors.lastname: Tugaĭ
authors.forename: V P
authors.initials: VP
authors.lastname: Zimina
authors.forename: A N
authors.initials: AN
authors.lastname: Zakharchenko
mesh_terms: D000588:Amines / Q000737:chemistry*; D000818:Animals; D001692:Biological Transport; D002118:Calcium / Q000378:metabolism*; D015220:Calcium Channels / Q000378:metabolism; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D005022:Ethyldimethylaminopropyl Carbodiimide / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D015640:Ion Channel Gating / Q000187:drug effects; D007700:Kinetics; D011817:Rabbits; D012519:Sarcoplasmic Reticulum / Q000187:drug effects / Q000378:metabolism*; D014302:Trinitrobenzenesulfonic Acid / Q000737:chemistry
chemical_list: D000588:Amines; D015220:Calcium Channels; D014302:Trinitrobenzenesulfonic Acid; D005022:Ethyldimethylaminopropyl Carbodiimide; D002118:Calcium
vernacular_title: Izmenenie passivnogo vkhoda Ca2+ v vezikuly sarkoplazmaticheskogo retikuluma v rezul'tate khimicheskoĭ modifikatsii poverkhnostnykh aminogrupp.