Is "Campylobacter upsaliensis" an unrecognised cause of human diarrhoea?
For 3 years a filtration system for the isolation of "new" campylobacter was included in the culture protocol of 15,185 stool specimens. "C upsaliensis" was isolated in 99 patients, C jejuni subsp doylei in 4, and C hyointestinalis in 2. "C upsaliensis" was the only organism isolated in 83 patients. Clinical information was available for 77 out of these 83 patients. 92% of the patients had diarrhoea; vomiting and fever were rare (14% and 7%, respectively); the onset was mostly sudden; and the symptoms usually lasted for less than a week. Gross or occult blood was present in a quarter of cases and neutrophils were detected in faecal smears in about a fifth. "C upsaliensis" may be an unrecognised and frequent cause of diarrhoea in man, and selective isolation media should be combined with non-selective isolation systems.
Goossens
H
H
WHO Collaborating Centre for Enteric Campylobacter, St Pieters University Hospital, Brussels, Belgium.
Vlaes
L
L
De Boeck
M
M
Pot
B
B
Kersters
K
K
Levy
J
J
De Mol
P
P
Butzler
J P
JP
Vandamme
P
P
D000328:Adult; D015373:Bacterial Typing Techniques; D001530:Belgium / Q000453:epidemiology; D002167:Campylobacter / Q000145:classification / Q000302:isolation & purification; D002169:Campylobacter Infections / Q000150:complications* / Q000453:epidemiology; D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology / Q000209:etiology* / Q000382:microbiology; D004641:Emigration and Immigration; D005069:Evaluation Studies as Topic; D005243:Feces / Q000382:microbiology; D005374:Filtration / Q000295:instrumentation; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008875:Middle Aged; D011446:Prospective Studies; D012189:Retrospective Studies; D012621:Seasons