title: Effect of a lipid-rich fraction from boiled coffee on serum cholesterol.
abstract: Scandinavian-style boiled coffee, which raises serum cholesterol, was found to contain more lipid material than drip filter coffee, which does not. Ten volunteers consumed a lipid-enriched fraction from boiled coffee for six weeks: the supplement provided 77 g of water, 1.3 g of lipid, and 1.6 g of other solids per day. Serum cholesterol rose in every subject; the mean rise was 0.74 mmol/l after three weeks (range -0.09 to 1.48 mmol/l) and 1.06 SD 0.37 mmol/l or 23% after six weeks (range 0.48 to 1.52 mmol/l). The increase was mainly due to low-density-lipoprotein cholesterol, which rose by 29%, but very-low-density lipoprotein cholesterol was also raised, as evidenced by a 55% rise in triglycerides. High-density-lipoprotein cholesterol was unchanged. After supplementation had ended, lipid levels returned to baseline. Boiled coffee thus contains a lipid that powerfully raises serum cholesterol.
authors.affiliation: Department of Human Nutrition, Agricultural University, Wageningen, The Netherlands.
authors.forename: P L
authors.initials: PL
authors.lastname: Zock
authors.forename: M B
authors.initials: MB
authors.lastname: Katan
authors.forename: M P
authors.initials: MP
authors.lastname: Merkus
authors.forename: M
authors.initials: M
authors.lastname: van Dusseldorp
authors.forename: J L
authors.initials: JL
authors.lastname: Harryvan
mesh_terms: D000328:Adult; D002784:Cholesterol / Q000097:blood*; D003069:Coffee; D002149:Energy Intake; D005069:Evaluation Studies as Topic; D005260:Female; D006358:Hot Temperature; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood / Q000209:etiology; D008055:Lipids / Q000008:administration & dosage* / Q000302:isolation & purification; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D013997:Time Factors
chemical_list: D003069:Coffee; D008055:Lipids; D008077:Lipoproteins, LDL; D002784:Cholesterol