title: [Problems for discussion in the development of candidal granulomas in the liver].
abstract: Controversial aspects of the development of infectious, in particular mycotic granulomas in the liver of laboratory animals (mice and rats) are discussed. Liver is the organ which is frequently used as a model for studying mechanisms and dynamics of the granulomatous inflammation. A high reactivity of the liver macrophagal system is noted and its ready response by granuloma formation to the bacterial cells, their walls and wall polysaccharide complexes. The expedience of revision of the criteria adopted for granuloma identification is doubted.
authors.forename: V L
authors.initials: VL
authors.lastname: Bykov
mesh_terms: D000818:Animals; D002177:Candidiasis / Q000473:pathology*; D004195:Disease Models, Animal; D006099:Granuloma / Q000473:pathology*; D007249:Inflammation / Q000473:pathology; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000473:pathology*; D008264:Macrophages / Q000473:pathology; D051379:Mice; D051381:Rats
vernacular_title: Diskussionnye voprosy razvitiia kandidoznykh granulem v pecheni.