[Experimental parvovirus infection of puppies: immunohistological findings].
Formalin-fixed tissue samples obtained from puppies experimentally infected with canine parvovirus type 2 (CPV-2) were investigated immunohistologically with the direct immunoperoxidase method. Besides cardiac muscle and lymphatic tissues, bone marrow, intestine, liver, kidney, pancreas and to a lesser degree lung stained positive for viral antigen and are considered as sites of viral replication. The distribution of viral antigen reveals a tropism of CPV-2 to numerous organs in puppies infected during the first week of life.
Vlemmas
I
I
Institut für Pathologie der Tierärztlichen Fakultät Thessaloniki, Griechenland.
Wohlsein
P
P
Trautwein
G
G
Kanakudis
G
G
Tsangaris
T
T
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis*; D004283:Dog Diseases / Q000382:microbiology*; D004285:Dogs; D007150:Immunohistochemistry; D010321:Parvoviridae / Q000276:immunology* / Q000502:physiology; D010322:Parvoviridae Infections / Q000382:microbiology / Q000662:veterinary*; D014779:Virus Replication
D000956:Antigens, Viral
Experimentelle Parvovirusinfektion von Hundewelpen: Immunohistologische Befunde.