A case of transient hyperphosphatasaemia of infancy associated with a probable allergic disorder.
Serum alkaline phosphatase (ALP) activity was found to be grossly elevated (8594 U/L) in a 2-year-old female child, returning towards normal during the subsequent 2 months. Electrophoresis revealed two bands of ALP activity; isoenzyme analysis identified the cathodic band as being of bone origin and the anodic band as sialylated liver ALP. Whilst the aetiology of transient hyperphosphataemia remains unclear a probable allergic disorder appears to be a contributory factor in this patient.
Tanishima
K
K
Department of Clinical Laboratory Sciences, School of Allied Medical Professions, Kanazawa University, Japan.
Ying
Q
Q
Hashimoto
T
T
Nagata
M
M
Matsubara
F
F
Miyawaki
T
T
D000469:Alkaline Phosphatase / Q000097:blood*; D002112:Calcifediol / Q000097:blood; D002116:Calcitonin / Q000097:blood; D002675:Child, Preschool; D004529:Egg White; D004591:Electrophoresis, Polyacrylamide Gel; D004795:Enzyme Stability; D005260:Female; D005512:Food Hypersensitivity / Q000097:blood*; D006801:Humans; D007231:Infant, Newborn; D007527:Isoenzymes / Q000097:blood; D010281:Parathyroid Hormone / Q000097:blood
D007527:Isoenzymes; D010281:Parathyroid Hormone; D002116:Calcitonin; D000469:Alkaline Phosphatase; D002112:Calcifediol