Effect of benzyl viologen on the fatty acid composition of rat liver.
The influence of subacute treatment with benzyl viologen (a stimulator of free radical production in cells) on the fatty acid content of rat liver has been analyzed. Lipid storage, essentially characterized by lamellated inclusions, developed as we reported previously (Muriana et al., Exp. Pathol., 32 (1987) 65-72). A substantial increase in liver total lipid, phospholipids and triacylglycerols was found during viologen treatment in rats. The composition in fatty acids was profoundly influenced by the experimental conditions, but to different degrees in different lipid classes.
Ruiz-Gutierrez
V
V
Instituto de la Grasa y sus Derivados (C.S.I.C.), Sevilla, Spain.
Muriana
F J
FJ
Quintero
F J
FJ
D000818:Animals; D001594:Benzyl Viologen / Q000009:adverse effects*; D002788:Cholesterol Esters / Q000378:metabolism; D005227:Fatty Acids / Q000378:metabolism*; D050356:Lipid Metabolism; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D010743:Phospholipids / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D014280:Triglycerides / Q000378:metabolism
D002788:Cholesterol Esters; D005227:Fatty Acids; D010743:Phospholipids; D014280:Triglycerides; D001594:Benzyl Viologen