title: Binswanger's disease and normal-pressure hydrocephalus. Clinical and neuropsychological comparison.
abstract: We investigated the clinical and cognitive aspects of patients with normal-pressure hydrocephalus and possible Binswanger's disease. We studied 19 patients with normal-pressure hydrocephalus and 19 patients with Binswanger's disease, comparing them with the same number of matched controls. The patients with normal-pressure hydrocephalus had a later age and more frequent gait disturbance at the onset, shorter duration of the illness, rare signs of vascular disturbances, and more frequent severe mental deterioration. Ventricular enlargement may play a role in determining the more rapid and worse clinical course of normal-pressure hydrocephalus.
authors.affiliation: Institute of Neurology, University of Bologna, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Gallassi
authors.forename: A
authors.initials: A
authors.lastname: Morreale
authors.forename: P
authors.initials: P
authors.lastname: Montagna
authors.forename: T
authors.initials: T
authors.lastname: Sacquegna
authors.forename: R
authors.initials: R
authors.lastname: Di Sarro
authors.forename: E
authors.initials: E
authors.lastname: Lugaresi
mesh_terms: D000368:Aged; D001927:Brain Diseases / Q000150:complications* / Q000503:physiopathology / Q000523:psychology; D003072:Cognition Disorders / Q000209:etiology; D003704:Dementia / Q000150:complications* / Q000503:physiopathology / Q000523:psychology; D005260:Female; D006801:Humans; D006850:Hydrocephalus, Normal Pressure / Q000150:complications* / Q000503:physiopathology / Q000523:psychology; D008297:Male; D001523:Mental Disorders / Q000209:etiology; D008875:Middle Aged; D009483:Neuropsychological Tests; D014706:Verbal Learning