[The detection of neutrophilic myeloperoxidase in the skeletal muscles of rats after muscle activity].
Rat muscle infiltration by neutrophils after muscle activity (MA) was investigated on myeloperoxidase (MPO) concentration. MPO distribution in muscle subcellular fractions was also studied. Increase of MPO concentration in skeletal muscles was discovered after MA. Its maximum was determined within 1-5 days of the rest. This fact can be considered as an evidence of neutrophil influx in muscle tissue. The electroral MPO concentration increase in plasmalemma membrane fraction after MA was shown. In vitro MPO was able to catalyze 125I inclusion in membrane material. These results give a possibility to propose that neutrophil MPO can have a certain significance in muscle tissue damage by haloid joining to plasmalemma proteins.
Morozov
V I
VI
Tsyplenkov
P V
PV
Rogozkin
V A
VA
D000818:Animals; D002469:Cell Separation; D008297:Male; D009132:Muscles / Q000737:chemistry / Q000201:enzymology*; D009504:Neutrophils / Q000737:chemistry / Q000201:enzymology*; D009195:Peroxidase / Q000032:analysis*; D005082:Physical Exertion / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D013550:Swimming
D009195:Peroxidase
Vyiavlenie mieloperoksidazy neĭtrofilov v skeletnykh myshtsakh krys posle myshchnoĭ deiatel'nosti.