title: Comparative study of enzyme-linked immunosorbent assay and radioimmunoassay techniques in determining serum placental protein 14 levels in gynecologic patients.
abstract: A comparative analysis of radioimmunoassay (RIA) and enzyme-linked immunosorbent assay (ELISA) techniques in determining placental protein 14 (PP14) levels in gynecologic patients was performed. Serum PP14 levels were assessed in the patients in the last period of gestation, during menopause and in healthy nonpregnant controls. The possible discrepancy in PP14 levels was also examined in gynecologic patients with benign and malignant tumors. Both RIA and ELISA techniques proved to be sufficiently sensitive to measure PP14 concentration.
authors.affiliation: Department of Biochemistry, Second Medical Institute, Moscow, USSR.
authors.forename: L A
authors.initials: LA
authors.lastname: Scherbakova
authors.forename: P M
authors.initials: PM
authors.lastname: Göcze
authors.forename: G A
authors.initials: GA
authors.lastname: Olefirenko
authors.forename: G N
authors.initials: GN
authors.lastname: Than
authors.forename: D G
authors.initials: DG
authors.lastname: Szabò
authors.forename: D D
authors.initials: DD
authors.lastname: Petrunin
authors.forename: Y S
authors.initials: YS
authors.lastname: Tatarinov
authors.forename: I F
authors.initials: IF
authors.lastname: Csaba
mesh_terms: D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005315:Fetal Diseases / Q000097:blood; D000071816:Glycodelin; D006023:Glycoproteins; D006801:Humans; D008593:Menopause; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood; D011257:Pregnancy Proteins / Q000097:blood*; D011863:Radioimmunoassay
chemical_list: D000071816:Glycodelin; D006023:Glycoproteins; C045246:PAEP protein, human; D011257:Pregnancy Proteins