title: [Evaluation of molluscicidal effect of nicotinanilide against Oncomelania snails].
abstract: Both nicotinanilide hydrochloride and nicotinanilide sulfate are water-soluble, their IC50 and LC90 against Oncomelania snails being around 0.3 mg/L and 0.5 mg/L, respectively, during 24 hour exposure at 25 degrees C followed by a 7-day recovery period. The laboratory tests and field trials showed that over 90% of snails were killed within 3 days exposure at 1-2 mg/L, and that 18.4%-100% snails on moist soil were killed at over 20 degrees C, exposed to spraying dosage of 1-2 g/m2 for 1-3 days. The chemical is highly effective against snails eggs at early stage (cell stage). The LC50 of nicotinanilide to Aristichthys nobilis and Pseudorasbora parva is about 200 mg/L. The acute oral LD50 in mice is about 2 g/kg. Plants tolerate the chemical at 1-2 g/m2, but some leaves wilted at greater than or equal to 5 g/m2, dicotyledon in particular. Dermatitis has been reported in individuals frequently exposing to nicotinanilide wettable powder during massive spraying.
authors.affiliation: Institute of Parasitic Diseases, Zhejiang Academy of Medical Sciences.
authors.forename: Z P
authors.initials: ZP
authors.lastname: Chen
authors.forename: H Q
authors.initials: HQ
authors.lastname: Tao
authors.forename: D S
authors.initials: DS
authors.lastname: Hua
authors.forename: B R
authors.initials: BR
authors.lastname: Shen
authors.forename: H L
authors.initials: HL
authors.lastname: Chan
mesh_terms: D000818:Animals; D005399:Fishes; D008975:Molluscacides; D009539:Nicotinic Acids; D012908:Snails
chemical_list: D008975:Molluscacides; D009539:Nicotinic Acids; C038997:nicotinanilide