title: Isolated pulmonary Goodpasture syndrome.
abstract: The case of a 13-year-old girl with Goodpasture syndrome is reported. The presentation at this age with only pulmonary hemorrhage is unusual among Goodpasture syndrome patients. The case illustrates well the diagnostic difficulties in Goodpasture syndrome. The choices of treatment modalities available for this disease and the results and risks of such treatment options are reviewed. A discussion and classification of diffuse pulmonary hemorrhage is presented. The case emphasizes that Goodpasture syndrome should be considered in the differential diagnosis of diffuse pulmonary hemorrhage in spite of a lack of renal abnormalities and that serum anti-glomerular basement membrane antibody testing can be of great help in confirming the diagnosis.
authors.affiliation: Department of Pathology, University of Wisconsin Hospital and Clinics, Madison 53792.
authors.forename: P
authors.initials: P
authors.lastname: Harrity
authors.forename: E
authors.initials: E
authors.lastname: Gilbert-Barness
authors.forename: A
authors.initials: A
authors.lastname: Cabalka
authors.forename: R
authors.initials: R
authors.lastname: Hong
authors.forename: J
authors.initials: J
authors.lastname: Zimmerman
mesh_terms: D000293:Adolescent; D019867:Anti-Glomerular Basement Membrane Disease / Q000175:diagnosis / Q000209:etiology / Q000473:pathology*; D001323:Autoantibodies / Q000097:blood; D001485:Basement Membrane / Q000276:immunology; D005260:Female; D006470:Hemorrhage / Q000145:classification / Q000473:pathology*; D006801:Humans; D007678:Kidney Glomerulus / Q000276:immunology; D008171:Lung Diseases / Q000145:classification / Q000473:pathology*
chemical_list: D001323:Autoantibodies