title: Successful small-bowel/liver transplantation.
abstract: A patient with the short-gut syndrome and antithrombin III deficiency underwent small bowel and liver grafting a year ago. Transient, mild graft-versus-host disease and intestinal rejection occurred within 2 months of grafting and were easily managed. Parenteral nutrition was discontinued 8 weeks after surgery. The patient has maintained normal nutritional indices while on an unrestricted oral diet. Small-bowel/liver grafting is feasible for patients with the short-gut syndrome and associated liver disorders. Further experience is needed to determine the specific risks, benefits, and general applicability of this procedure.
authors.affiliation: Department of Medicine, University of Western Ontario, London, Canada.
authors.forename: D
authors.initials: D
authors.lastname: Grant
authors.forename: W
authors.initials: W
authors.lastname: Wall
authors.forename: R
authors.initials: R
authors.lastname: Mimeault
authors.forename: R
authors.initials: R
authors.lastname: Zhong
authors.forename: C
authors.initials: C
authors.lastname: Ghent
authors.forename: B
authors.initials: B
authors.lastname: Garcia
authors.forename: C
authors.initials: C
authors.lastname: Stiller
authors.forename: J
authors.initials: J
authors.lastname: Duff
mesh_terms: D000328:Adult; D005223:Fats / Q000032:analysis; D005243:Feces / Q000032:analysis; D005260:Female; D006801:Humans; D007421:Intestine, Small / Q000637:transplantation*; D008099:Liver / Q000378:metabolism; D016031:Liver Transplantation / Q000009:adverse effects; D008286:Malabsorption Syndromes / Q000601:surgery*; D015166:Monitoring, Immunologic; D011379:Prognosis; D012086:Reoperation; D012778:Short Bowel Syndrome / Q000601:surgery*; D013908:Thoracotomy / Q000009:adverse effects; D014994:Xylose / Q000652:urine
chemical_list: D005223:Fats; D014994:Xylose