Miliary spread of malignant pleural mesothelioma without a clinically identifiable pleural tumour.
A 44-year-old man with past minor exposure to blue asbestos presented with supraclavicular lymphadenopathy and miliary shadowing on his chest radiograph. Cytology and electronmicroscopy on material obtained by fine needle aspiration from his cervical lymph node revealed malignant mesothelioma. Malignant mesothelioma cells were also present in bronchoalveolar lavage fluid and on transbronchial lung biopsy. At autopsy the right pleural cavity was studded with small tumour nodules. This case demonstrates that malignant mesothelioma may present as metastatic disease and without evidence on conventional investigations of a primary pleural tumour.
Musk
A W
AW
Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, WA.
Dewar
J
J
Shilkin
K B
KB
Whitaker
D
D
D000328:Adult; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis / Q000473:pathology; D008297:Male; D008654:Mesothelioma / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D010997:Pleural Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D011859:Radiography