[A comparative study of propofol and diazepam used as sedatives in gastroscopy].
A material of 100 patients aged 18-70 years, ASA groups 1-2, who were otherwise healthy with slight generalized sequelae of their illness but without limitations in their usual habits, who were admitted for gastroscopy were randomized to sedation with either diazepam or propofol. Prior to the examination, 0.2 mg/kg diazepam or 1 mg/kg propofol was administered. If necessary, this was supplemented with half of the initial dosage. No difference were found in the sedation. Patients in the propofol group remembered the surgeon's information significantly better and woke significantly more rapidly. Propofol caused significantly more pain on injection. We consider that propofol can be employed for outpatient gastroscopy.
Møller
A L
AL
Anaestesiafdelingen og abdominalkirurgisk afedling, Aalborg Sygehus Syd.
Larsen
U T
UT
Andersen
J B
JB
Olesen
A S
AS
D000293:Adolescent; D000328:Adult; D000368:Aged; D003975:Diazepam / Q000008:administration & dosage*; D004341:Drug Evaluation; D005260:Female; D005773:Gastroscopy; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D015742:Propofol / Q000008:administration & dosage*
D006993:Hypnotics and Sedatives; D003975:Diazepam; D015742:Propofol
En sammenlignende undersøgelse mellem propofol og diazepam, anvendt som sedering til gastroskopi.