Sulpiride-induced tardive dystonia.
Sulpiride is a selective D2-receptor antagonist with antipsychotic and antidepressant properties. Although initially thought to be free of extrapyramidal side effects, sulpiride-induced tardive dyskinesia and parkinsonism have been reported occasionally. We studied a 37-year-old man who developed persistent segmental dystonia within 2 months after starting sulpiride therapy. We could not find any previous reports of sulpiride-induced tardive dystonia.
Miller
L G
LG
Department of Family Medicine, Baylor College of Medicine, Houston, Texas 77030.
Jankovic
J
J
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004409:Dyskinesia, Drug-Induced / Q000209:etiology*; D004421:Dystonia / Q000139:chemically induced*; D006801:Humans; D008297:Male; D011618:Psychotic Disorders / Q000188:drug therapy; D011954:Receptors, Dopamine / Q000187:drug effects; D017448:Receptors, Dopamine D2; D013469:Sulpiride / Q000009:adverse effects* / Q000627:therapeutic use
D014150:Antipsychotic Agents; D011954:Receptors, Dopamine; D017448:Receptors, Dopamine D2; D013469:Sulpiride