title: [The possible sources of hyperandrogenism in hirsutism in girls].
abstract: The purpose of the investigation is to elucidate the role of adrenal androgens in the development of the syndrome of polycystic ovaries in girls of pubertal age. Clinical manifestations of disease and hormonal indices, the levels of testosterone, 17-oxyprogesterone and cortisol with ACTH and dexamethasone tolerance tests were investigated. A significant rise of the level of testosterone and 17-oxyprogesterone was revealed in response to ACTH administration in 30% of the examinees indicating the adrenal genesis of hyperandrogenism. A characteristic feature of the development of disease in this group of patients is early development of hirsutism followed by disturbed menstrual function.
authors.forename: T V
authors.initials: TV
authors.lastname: Semicheva
authors.forename: G S
authors.initials: GS
authors.lastname: Kolesnikova
authors.forename: A A
authors.initials: AA
authors.lastname: Pishchulin
authors.forename: S S
authors.initials: SS
authors.lastname: Pankova
authors.forename: A D
authors.initials: AD
authors.lastname: Dobracheva
authors.forename: N S
authors.initials: NS
authors.lastname: Martysh
mesh_terms: D000293:Adolescent; D000311:Adrenal Glands / Q000187:drug effects / Q000503:physiopathology; D000324:Adrenocorticotropic Hormone; D000728:Androgens / Q000097:blood*; D003907:Dexamethasone; D005260:Female; D006628:Hirsutism / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D006728:Hormones / Q000097:blood; D006801:Humans; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000175:diagnosis / Q000209:etiology; D013997:Time Factors
chemical_list: D000728:Androgens; D006728:Hormones; D003907:Dexamethasone; D000324:Adrenocorticotropic Hormone
vernacular_title: Vozmozhnye istochniki giperandrogenii pri girsutizme u devochek.