title: [Postnatal weight loss in ventilated premature infants below 1500 g: significance of renal and extra-renal fluid loss].
abstract: In 9 ventilated preterm infants (birth weight 810-1310 g, gestational age 26-30 weeks) we measured total body water (D2O dilution), extracellular volume (sucrose dilution) and renal function parameters at birth and when postnatal weight loss exceeded 5% of birth weight together with day to day changes of weight, fluid balance, and serum electrolytes. A significant postnatal weight loss (-89 +/- 47 g) occurred together with a reduction of total body water (-102 +/- 95 ml) and extracellular volume (-98 +/- 59 ml) in the first three days of life. The intracellular volume did not change. At the same time fluid balance was negative due to a high extrarenal water loss on day 1 and an increasing diuresis on the following days. The serum sodium concentration remained unchanged during postnatal water loss, because the negative fluid balance was accompanied by a negative sodium balance.
authors.affiliation: Neonatologie, Frauenklinik Grosshadern, Ludwig-Maximilians-Universität, München.
authors.forename: K
authors.initials: K
authors.lastname: Bauer
authors.forename: M
authors.initials: M
authors.lastname: Götz
authors.forename: A
authors.initials: A
authors.lastname: Roithmaier
authors.forename: A
authors.initials: A
authors.lastname: Prölss
authors.forename: G
authors.initials: G
authors.lastname: Bovermann
authors.forename: H
authors.initials: H
authors.lastname: Versmold
mesh_terms: D001724:Birth Weight / Q000502:physiology*; D004231:Diuresis / Q000502:physiology; D005110:Extracellular Space / Q000502:physiology; D005919:Glomerular Filtration Rate / Q000502:physiology; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000503:physiopathology*; D007424:Intracellular Fluid / Q000502:physiology; D007668:Kidney / Q000503:physiopathology; D012121:Respiration, Artificial; D012127:Respiratory Distress Syndrome, Newborn / Q000503:physiopathology; D012964:Sodium / Q000097:blood; D014882:Water-Electrolyte Balance / Q000502:physiology*; D015431:Weight Loss / Q000502:physiology*
chemical_list: D012964:Sodium
vernacular_title: Postnatale Gewichtsabnahme beatmeter Frühgeborener unter 1500 g: Bedeutung des renalen und extrarenalen Flüssigkeitsverlusts.