Study of sequences of DNA of the human papilloma virus genotypes 6 and 16 in patients with cancer of vulva and cervix uteri.
Puntaction hybridization method was used to determine the incidence of the human papilloma virus infection in cases with the squamous cell cancer of the vulva and cervix uteri. The presence of sequences of DNA of the HPV genotype and 16 was found in 74.2% of cases, which points to a suspicion for the involvement of the above viruses in etiology of cervix uteri cancer, as well as vulva cancer.
Bokhman
J V
JV
Petròv Research Institute of Oncology, USSR Ministry of Health, Leningrad.
Kuznetsov
O K
OK
Maximov
S J
SJ
Tadzhibayeva
J T
JT
Aron
P A
PA
Vasilyev
B V
BV
Migunova
B V
BV
Tkeshmelashvili
V G
VG
D015344:DNA Probes, HPV; D004279:DNA, Viral / Q000032:analysis* / Q000235:genetics; D005260:Female; D005838:Genotype; D006801:Humans; D008875:Middle Aged; D009693:Nucleic Acid Hybridization; D027383:Papillomaviridae / Q000235:genetics*; D014412:Tumor Virus Infections / Q000382:microbiology*; D002583:Uterine Cervical Neoplasms / Q000382:microbiology*; D014846:Vulvar Neoplasms / Q000382:microbiology*
D015344:DNA Probes, HPV; D004279:DNA, Viral