Primary skin malignancy with features suggestive of dendritic reticulum cell differentiation.
A 72-year-old man developed recurring skin lesions. Multiple biopsies revealed a skin malignancy with histologic features of lymphoma. The bone marrow was subsequently replaced by tumor. Immunologic and ultrastructural features of the tumor cells suggested dendritic reticulum cell differentiation.
Strickler
J G
JG
Department of Laboratory Medicine, University of Minnesota School of Medicine, Minneapolis 55455.
Parkin
J L
JL
Schmidt
C M
CM
Hurd
D D
DD
D000368:Aged; D015703:Antigens, CD / Q000032:analysis; D000943:Antigens, Differentiation / Q000032:analysis; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis; D001853:Bone Marrow / Q000473:pathology; D018801:CD2 Antigens; D015704:CD4 Antigens / Q000032:analysis; D002454:Cell Differentiation; D002466:Cell Nucleolus / Q000473:pathology; D002467:Cell Nucleus / Q000473:pathology; D002843:Chromatin / Q000473:pathology; D003593:Cytoplasm / Q000473:pathology; D003713:Dendritic Cells / Q000473:pathology*; D006649:Histocompatibility Antigens / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D017493:Leukocyte Common Antigens; D008223:Lymphoma / Q000473:pathology; D008297:Male; D008854:Microscopy, Electron; D011971:Receptors, Immunologic / Q000032:analysis; D012878:Skin Neoplasms / Q000473:pathology*
D015703:Antigens, CD; D000943:Antigens, Differentiation; D000945:Antigens, Differentiation, T-Lymphocyte; D018801:CD2 Antigens; D015704:CD4 Antigens; D002843:Chromatin; D006649:Histocompatibility Antigens; D011971:Receptors, Immunologic; D017493:Leukocyte Common Antigens