Autonomic nervous system dysfunction and volume nonresponsive hypotension in hemodialysis patients.
Studies were conducted in 9 dialysis patients with volume-nonresponsive hypotension, 6 dialysis patients with volume-responsive hypotension and in 10 normal subjects in an effort to evaluate the role of dysfunction of the autonomic nervous system (ANS) in the genesis of volume-nonresponsive hypotension. ANS function was evaluated by the Valsalva maneuver, handgrip exercise, and by the response of heart rate and blood pressure to change of posture from a supine to a standing position. Patients with volume-nonresponsive hypotension displayed significant derangements in the function of ANS as compared to normal subjects and to patients with volume-responsive hypotension. Data show that dysfunction of ANS plays an important role in the genesis of volume-nonresponsive hypotension in dialysis patients.
Stojceva-Taneva
O
O
Department of Nephrology, Medical Faculty, University of Skopje, Yugoslavia.
Masin
G
G
Polenakovic
M
M
Stojcev
S
S
Stojkovski
L
L
D001342:Autonomic Nervous System Diseases / Q000150:complications* / Q000175:diagnosis; D015444:Exercise; D005260:Female; D006801:Humans; D007022:Hypotension / Q000209:etiology*; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011187:Posture; D006435:Renal Dialysis / Q000009:adverse effects*; D014636:Valsalva Maneuver; D014883:Water-Electrolyte Imbalance / Q000503:physiopathology