The hormones--a model for a new understanding of cell differentiation process. Part I. Differentiation--an individual cell option?
From the beginning I want to explain some interesting notions about cytodifferentiation, these being seen, in my view, like an Instructive Informatory Theory. Then, I tried to present the sustaining arguments for an extracellular differentiation. These arguments reveal that final decision in differentiation process are the receptor molecules. Therefore, I present some actual questions arisen about the correlations between receptors and secondary messengers. The hormones action models are the single way to clear up the vagueness about the nucleus-receptor connection.
Ciubotaru
M
M
Medico-Pharmaceutical Institute, Chair of Endocrinology, Bucharest, Romania.
D000818:Animals; D002454:Cell Differentiation / Q000502:physiology; D004247:DNA / Q000502:physiology; D005057:Eukaryotic Cells / Q000166:cytology*; D005775:Gastrula / Q000166:cytology; D005786:Gene Expression Regulation / Q000502:physiology; D006728:Hormones / Q000502:physiology*; D006801:Humans; D007257:Information Theory; D008954:Models, Biological; D011956:Receptors, Cell Surface / Q000502:physiology; D015290:Second Messenger Systems / Q000502:physiology
D006728:Hormones; D011956:Receptors, Cell Surface; D004247:DNA