title: [The modelling of hepatitis A and of enterally transmitted non-A, non-B hepatitis (hepatitis E) in Saguinus mystax tamarins].
abstract: A comparative study of hepatitis infection caused by human hepatitis A virus (MS-1 strain), simian hepatitis A virus (AGM-27 strain), and enterically transmitted non-A, non-B hepatitis virus (Tashkent-1435 strain) was carried out. Susceptibility of tamarins to the AGM-27 and Tashkent-1435 as well as to MS-1 strain was demonstrated. All the strains induced an acute infection characterized by serum alanine aminotransferase (ALT) elevation, virus excretion and antibody response. Certain differences in the course of infection caused by these strains were observed in the duration of the incubation period and ALT profiles.
authors.forename: V F
authors.initials: VF
authors.lastname: Poleshchuk
authors.forename: M S
authors.initials: MS
authors.lastname: Balaian
authors.forename: A G
authors.initials: AG
authors.lastname: Andzhaparidze
authors.forename: A V
authors.initials: AV
authors.lastname: Sobol'
authors.forename: V P
authors.initials: VP
authors.lastname: Dokin
authors.forename: T V
authors.initials: TV
authors.lastname: Guliaeva
authors.forename: I P
authors.initials: IP
authors.lastname: Titova
mesh_terms: D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D000956:Antigens, Viral / Q000032:analysis; D002522:Chlorocebus aethiops / Q000382:microbiology; D004195:Disease Models, Animal; D005243:Feces / Q000382:microbiology; D005260:Female; D006506:Hepatitis A / Q000201:enzymology / Q000209:etiology* / Q000382:microbiology; D016751:Hepatitis E / Q000209:etiology* / Q000382:microbiology; D006507:Hepatovirus / Q000276:immunology / Q000302:isolation & purification; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis; D008297:Male; D012452:Saguinus; D013997:Time Factors
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral; D007075:Immunoglobulin M; D000410:Alanine Transaminase
vernacular_title: Modelirovanie gepatita A i énteral'no peredaiushchegosia gepatita ni A, ni B (gepatita E) na tamarinakh Saguinus mystax.