title: [Structural changes in the nuclei of human lymphocytes under the effects of ionizing radiation within the range of doses that cause the adaptive response].
abstract: Low-level radiation either from external, or from incorporated sources is shown to cause a non-monotonous change in some intranuclear parameters of human peripheral blood lymphocytes. For instance, radiation induces changes in the parameters that characterize the location of perecentromeric regions within the interphase nucleus and a non-monotonous increase in nuclear sizes. The exposure to doses exceeding 5 cGy impairs the relationship between the nuclear sizes and location therein of the perecentromeric regions of interphase chromosomes which exist in the control and after exposure to 2.5 cGy. Differences between the dose ranges of 1.5-3.5 and 17-25 cGy are manifested by the kinetics of restoration of the pattern of distribution of lymphocyte nuclear sizes.
authors.forename: T A
authors.initials: TA
authors.lastname: Talyzina
authors.forename: D M
authors.initials: DM
authors.lastname: Spitkovskiĭ
mesh_terms: D000220:Adaptation, Biological; D000328:Adult; D002467:Cell Nucleus / Q000187:drug effects / Q000528:radiation effects*; D002503:Centromere / Q000528:radiation effects; D002875:Chromosomes / Q000528:radiation effects; D006801:Humans; D066298:In Vitro Techniques; D007399:Interphase; D008214:Lymphocytes / Q000187:drug effects / Q000528:radiation effects*; D008297:Male; D008875:Middle Aged; D011829:Radiation Dosage; D011839:Radiation, Ionizing; D013936:Thymidine / Q000494:pharmacology
chemical_list: D013936:Thymidine
vernacular_title: Strukturnye izmeneniia iader limfotsitov cheloveka pri deĭstvii ioniziruiushchikh izlucheniĭ v diapazone doz, vyzyvaiushchikh adaptivnyĭ otvet.