title: Use and control of biotechnological methods.
abstract: The use of molecular virology is described. Emphasis is placed on molecular biology, especially methods involving gene technology. The respective techniques allow characterisation of viruses by molecular cloning and nucleotide sequencing as well as the development of new diagnostic tools and vaccines. Genetically engineered live viruses serve as examples to study potential risks of vaccines derived from such viruses.
authors.affiliation: Federal Research Centre for Virus Diseases of Animals, Tübingen, Federal Republic of Germany.
authors.forename: H J
authors.initials: HJ
authors.lastname: Thiel
authors.forename: E
authors.initials: E
authors.lastname: Pfaff
mesh_terms: D000818:Animals; D005537:Aphthovirus / Q000235:genetics; D001709:Biotechnology / Q000379:methods*; D003001:Cloning, Molecular; D005536:Foot-and-Mouth Disease / Q000175:diagnosis; D005818:Genetic Engineering / Q000662:veterinary; D005858:Germany; D012307:Risk Factors; D014730:Veterinary Medicine / Q000379:methods*; D014765:Viral Vaccines; D014773:Virology / Q000379:methods*
chemical_list: D014765:Viral Vaccines