title: Bladder and rectal dose of gynecologic high-dose-rate implants: comparison of orthogonal radiographic measurements with in vivo and CT-assisted measurements.
abstract: Bladder and rectal doses were retrospectively reviewed in 281 patients who underwent implantation of 575 gynecologic iridium-192 high-dose-rate devices. Dose measurements obtained with orthogonal radiography, in vivo thermoluminescent dosimetry, and computed tomography (CT)-assisted planning were compared. Measurements of bladder dose derived from radiographs revealed a significant difference between bladder neck dose and bladder base dose (P less than .0001). In 17% of cases, the dose to the bladder base was at least double the dose to the bladder neck. The mean dose to the rectum calculated from radiographs was 85.9% (cervix) and 90.2% (vaginal vault) of the prescribed fraction dose. The correlation coefficient factor between doses determined with orthogonal radiographs and doses determined with in vivo measurements was .9694. The dose to the bladder neck and to four rectal points determined with corresponding CT images revealed a deviation of 4% and 7%, respectively. However, calculations at the rectal wall cephalic to the specified rectal points showed higher doses to the rectum, with a ratio of 1-1.6. CT-assisted calculations at the bladder base also revealed doses that were higher than those obtained with radiographs alone by a ratio of 1.4-2.2. CT-assisted dosimetry is the method of choice.
authors.affiliation: Department of Radiotherapy, University Medical School Graz, Austria.
authors.forename: G F
authors.initials: GF
authors.lastname: Stuecklschweiger
authors.forename: K S
authors.initials: KS
authors.lastname: Arian-Schad
authors.forename: E
authors.initials: E
authors.lastname: Poier
authors.forename: J
authors.initials: J
authors.lastname: Poschauko
authors.forename: A
authors.initials: A
authors.lastname: Hackl
mesh_terms: D001918:Brachytherapy; D016889:Endometrial Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D007496:Iridium Radioisotopes / Q000627:therapeutic use; D011879:Radiotherapy Dosage; D012007:Rectum / Q000000981:diagnostic imaging / Q000528:radiation effects*; D012189:Retrospective Studies; D013819:Thermoluminescent Dosimetry; D014057:Tomography, X-Ray Computed; D001743:Urinary Bladder / Q000000981:diagnostic imaging / Q000528:radiation effects*; D002583:Uterine Cervical Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy*
chemical_list: D007496:Iridium Radioisotopes