Effect of hyperthermia on the internal microviscosity of erythrocytes and lymphocytes: a spin-label study.
The internal microviscosity of human erythrocytes and porcine lymphocytes was investigated, from the electron-spin resonance spectral characteristics of the nitroxyl spin probe, 4-amino-2,2,6,6-tetramethylpiperidinyloxy. Heat-induced permanent damage to cells was observed as an increase in the intracellular microviscosity of nucleate and enucleate cells. Induction of heat resistance was found for erythrocytes treated with a double heat shock.
Koter
M
M
Department of Biophysics, University of Lódź, Poland.
D000818:Animals; D001809:Blood Viscosity / Q000502:physiology*; D004578:Electron Spin Resonance Spectroscopy; D004912:Erythrocytes / Q000502:physiology*; D006358:Hot Temperature; D006801:Humans; D066298:In Vitro Techniques; D008214:Lymphocytes / Q000502:physiology*; D013113:Spin Labels; D013552:Swine
D013113:Spin Labels