[Should the parathyroid function be evaluated in a patient with calcium kidney stones? If so, when and why?].
About 7% of patients with calcium urolithiasis suffer from primary hyperparathyroidism. A systematic search for this diagnosis is therefore mandatory in such patients. Because hypercalcemia is often discrete or intermittent, determinations of calcium levels should be repeated at least thrice. Measurement of ionized calcium levels improves the detection of hypercalcemia. The biological diagnosis is based on the presence of hypercalcemia together with an increased plasma level of 1-84 intact parathormone (PTH). A PTH value still in the normal range but inappropriately elevated in the context of hypercalcemia could be sufficient for the diagnosis of primary hyperparathyroidism.
Gardin
J P
JP
Service d'Explorations Fonctionnelles, Université Pierre et Marie Curie, INSERM CJF 88-07, Hôpital Broussais, Paris.
Houillier
P
P
Borensztein
P
P
Paillard
M
M
D002118:Calcium / Q000097:blood*; D006801:Humans; D006934:Hypercalcemia / Q000097:blood* / Q000209:etiology; D006961:Hyperparathyroidism / Q000150:complications / Q000175:diagnosis*; D007669:Kidney Calculi / Q000097:blood* / Q000209:etiology; D010280:Parathyroid Glands / Q000503:physiopathology*; D010281:Parathyroid Hormone / Q000097:blood*
D010281:Parathyroid Hormone; D002118:Calcium
Faut-il évaluer la fonction parathyroïdienne d'un patient atteint de lithiase rénale calcique? Si oui, quand et pourquoi?