Oligomerizations of deoxyadenosine bis-phosphates and of their 3'-5', 3'-3', and 5'-5' dimers: effects of a pyrophosphate-linked, poly(T) analog.
A pyrophosphate-linked polynucleotide analog based on thymidine 3',5' bis-phosphate (pTp) catalyzes the oligomerization of activated dimers of pdAp in the presence of MgCl2. Although no catalysis of the oligomerization of the activated monomer (ImpdAplm) was observed in the presence of MgCl2, there was a significant stimulation of oligomerization by the template in the presence of MnCl2.
Visscher
J
J
Laboratory for Evolutionary Biology, Faculty of Science, University of Nijmegen, The Netherlands.
Bakker
C G
CG
Schwartz
A W
AW
D003838:Deoxyadenine Nucleotides / Q000737:chemistry*; D011756:Diphosphates; D007202:Indicators and Reagents; D011071:Poly T; D013698:Templates, Genetic
D003838:Deoxyadenine Nucleotides; D011756:Diphosphates; D007202:Indicators and Reagents; D011071:Poly T