[The action of tropic adenohypophyseal hormones when administered intraventricularly on rat behavioral reactions].
In experiments on rats the influence was studied of tropic hormones of adenohypophysis--somatotropin, thyrotropin and adrenocorticotropin (STH, ThTN and ACTH respectively) on the elaboration and extinction of conditioned reaction of active avoidance (CRAA) in Y-maze and behaviour in the open field under microinjections of hormones into the brain lateral ventricle (0.001-0.002 ME). It has been shown that all studied hormones improve animals learning at negative pain reinforcement; ThTH and ACTH retard it in contrast to STH, which accelerates the extinction of the elaborated CRAA; tropic hormones exert differentiated influence on rats behaviour in the open field. No distinct correlation was found between behavioural manifestation and the level of catecholamines in the rats hypothalamus.
Sapronov
N S
NS
Kudriashova
M F
MF
D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects / Q000502:physiology; D001522:Behavior, Animal / Q000187:drug effects* / Q000502:physiology; D002395:Catecholamines / Q000378:metabolism; D003214:Conditioning, Classical / Q000187:drug effects / Q000502:physiology; D013006:Growth Hormone / Q000494:pharmacology; D007031:Hypothalamus / Q000187:drug effects / Q000378:metabolism; D007276:Injections, Intraventricular; D008297:Male; D010908:Pituitary Hormones, Anterior / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D012054:Reinforcement, Psychology; D013972:Thyrotropin / Q000494:pharmacology
D002395:Catecholamines; D010908:Pituitary Hormones, Anterior; D000324:Adrenocorticotropic Hormone; D013972:Thyrotropin; D013006:Growth Hormone
Deĭstvie tropnykh gormonov adenogipofiza pri ikh vnutrizheludochkovom vvedenii na povedencheskie reaktsii u krys.