[Thyroid cancer and familial rectocolonic polyposis].
Thyroid carcinoma and familial intestinal polyposis are not accidentally associated. A new case is described which, along with the other 32 cases already published, reveals an incidence of thyroid carcinoma 100 times higher in patients with polyposis than in the general population, and 160 times higher in female patients under 35 years of age. Several features of these thyroid carcinomas can be pointed out: greatest incidence in women, occurrence at a young age, existence of a papillary tumor appearing independently from the evolution of the polyposis, and probably familial disease. It is therefore necessary to systematically examine the thyroid body in all subjects with familial intestinal polyposis.
de Mestier
P
P
Hôpital du Gardien-de-la-Paix, Paris.
D011125:Adenomatous Polyposis Coli / Q000235:genetics*; D002291:Carcinoma, Papillary / Q000235:genetics*; D015179:Colorectal Neoplasms / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000235:genetics*; D013964:Thyroid Neoplasms / Q000235:genetics*
Cancer thyroïdien et polypose recto-colique familiale.