Combination of fluoxetine with pemoline in the treatment of major depressive disorder.
Standard antidepressant drug treatments are unsuccessful in treating up to one-third of depressed patients. The authors describe the utility of combining the 5-hydroxytryptamine (5-HT) re-uptake blocker, fluoxetine (Prozac) with a psychostimulant, pemoline (Cylert), for some of these patients.
Metz
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A
New England Medical Center, Tufts University School of Medicine, Boston, MA 02111.
Shader
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RI
D000328:Adult; D003866:Depressive Disorder / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D005473:Fluoxetine / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D010389:Pemoline / Q000627:therapeutic use*
D005473:Fluoxetine; D010389:Pemoline