The use of oral labetalol in the treatment of arrhythmias associated with the long QT syndrome.
A 7-year-old white boy with the long QT syndrome began to experience recurrent syncope associated with torsade de pointes ventricular tachycardia in spite of beta-blocker therapy. The patient was therefore given a combined alpha- and beta-blocking agent (labetalol) with complete suppression of the syncopal episodes. This suggests a role for combined alpha- and beta-blocking agents in the therapy of arrhythmias associated with the long QT syndrome.
Grubb
B P
BP
Department of Medicine, Medical College of Ohio, Toledo 43560.
D000284:Administration, Oral; D002648:Child; D004562:Electrocardiography; D006801:Humans; D007741:Labetalol / Q000008:administration & dosage*; D008133:Long QT Syndrome / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D013575:Syncope / Q000209:etiology; D016171:Torsades de Pointes / Q000150:complications / Q000188:drug therapy*
D007741:Labetalol