title: [The effect of hydrocortisone on posttetanic potentiation in rat cerebral cortex slices and the molecular mechanisms of this effect].
abstract: The effect of hydrocortisone on posttetanic potentiation, Ca exchange, metabolism of phosphoinositides and phospholipids methylation, was studied. Hydrocortisone (10(-4) M) facilitated and prolonged the posttetanic potentiation. Incubation of slices in hydrocortisone for 90 sec elevated the incorporation of 32P-orthophosphate in polyphosphoinositide. Within 2 min of hydrocortisone action, the rate constant of Ca entry increased two-fold, transmembrane exchange fluxes of Ca increasing, too. Incorporation of 14C-methyl group in different phospholipids was considerably increased after 20-min hydrocortisone action.
authors.forename: N A
authors.initials: NA
authors.lastname: Emel'ianov
authors.forename: T R
authors.initials: TR
authors.lastname: Bagaeva
authors.forename: I A
authors.initials: IA
authors.lastname: Gerasimova
authors.forename: A A
authors.initials: AA
authors.lastname: Mokrushin
authors.forename: L I
authors.initials: LI
authors.lastname: Pavlinova
mesh_terms: D000818:Animals; D002118:Calcium / Q000378:metabolism; D002132:Calcium Radioisotopes; D002540:Cerebral Cortex / Q000187:drug effects* / Q000502:physiology; D006854:Hydrocortisone / Q000494:pharmacology*; D066298:In Vitro Techniques; D008297:Male; D008745:Methylation; D010716:Phosphatidylinositols / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
chemical_list: D002132:Calcium Radioisotopes; D010716:Phosphatidylinositols; D010743:Phospholipids; D002118:Calcium; D006854:Hydrocortisone
vernacular_title: Vliianie gidrokortizona na posttetanicheskuiu potentsiatsiiu v srezakh kory mozga krys i nekotorye molekuliarnye mekhanizmy étogo éffekta.