title: Successful pregnancy following allogeneic bone marrow transplantation after conditioning by thoraco-abdominal irradiation.
abstract: A 26-year-old woman delivered a normal child 5 years after bone marrow transplantation for severe aplastic anemia. The conditioning regimen comprised high dose cyclophosphamide and thoraco-abdominal irradiation (6 Gy). This and two previous cases demonstrate that normal pregnancy can follow total body or thoracoabdominal irradiation.
authors.affiliation: Département d'Hématologie, Hôpital Nord, St Priest en Jarez, France.
authors.forename: P
authors.initials: P
authors.lastname: Calmard-Oriol
authors.forename: C
authors.initials: C
authors.lastname: Dauriac
authors.forename: H
authors.initials: H
authors.lastname: Vu Van
authors.forename: M
authors.initials: M
authors.lastname: Lacroze
authors.forename: B
authors.initials: B
authors.lastname: Landriot
authors.forename: D
authors.initials: D
authors.lastname: Guyotat
mesh_terms: D000005:Abdomen / Q000528:radiation effects*; D000328:Adult; D000741:Anemia, Aplastic / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D016026:Bone Marrow Transplantation; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D011247:Pregnancy / Q000187:drug effects / Q000528:radiation effects*; D011256:Pregnancy Outcome; D013909:Thorax / Q000528:radiation effects*; D014184:Transplantation, Homologous; D014916:Whole-Body Irradiation
chemical_list: D003520:Cyclophosphamide