[The leader region of the Drosophila transposon MDG1 contains transcription termination sites].
The analysis of MDG1 transcription in Drosophila melanogaster cells discovered transcription termination sites in the leader region of the element. These termination sites are localized 1 kb downstream the transcription initiation site and contain long oligo (dA) blocks. The transcription termination is regulated in different cell types. The transient expression of the deletion mutants has shown that a small ORF in the MDG leader region can be translated. This points on possible transcription reinitiation during the process of reading the main ORF MDG1.
Cherkasova
V A
VA
Il'in
Iu V
IuV
D000818:Animals; D002872:Chromosome Deletion; D004247:DNA / Q000096:biosynthesis; D004251:DNA Transposable Elements / Q000502:physiology*; D004331:Drosophila melanogaster / Q000235:genetics*; D009154:Mutation / Q000235:genetics; D010957:Plasmids / Q000235:genetics; D015183:Restriction Mapping; D013728:Terminator Regions, Genetic / Q000235:genetics*
D004251:DNA Transposable Elements; D004247:DNA
Lidernaia oblast' retrotranspozona drozofily MDG1 soderzhit terminatsii transkriptsii.