Ranitidine and depression.
Three cases are described in which the cessation of the H2-antagonist ranitidine was followed by a rapid improvement in severe depressive symptoms. The literature concerning H2-receptor antagonists and depression is reviewed, and an alternative drug (omeprazole) for severe peptic ulceration is discussed.
Stocky
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A
Monash University Centre for Developmental Psychiatry, Clayton, Vic.
D000368:Aged; D003866:Depressive Disorder / Q000139:chemically induced* / Q000175:diagnosis / Q000523:psychology*; D004942:Esophagitis, Peptic / Q000188:drug therapy* / Q000523:psychology*; D005260:Female; D006801:Humans; D008016:Life Change Events; D011899:Ranitidine / Q000008:administration & dosage / Q000009:adverse effects*; D012008:Recurrence; D012307:Risk Factors; D012803:Sick Role; D013276:Stomach Ulcer / Q000188:drug therapy* / Q000523:psychology*; D013375:Substance Withdrawal Syndrome / Q000175:diagnosis* / Q000523:psychology*
D011899:Ranitidine