Glucose disappearance rates into peripheral tissues of adult rabbits (Silvilagus floridans), Wistar rats (Rattus rattus) and sand rats (Psammomys obesus) in relation to body weight and blood glucose concentration.
1. Glucose disappearance rates into peripheral tissues (RD) were measured in vivo in adult eviscerated, nephrectomized and adrenalectomized rabbits, Wistar rats and nondiabetic sand rats with physiological insulin concentrations in the blood. 2. The RD of Wistar rats was high (7.50 mg/kg/min) in comparison with that of rabbits (2.67 mg/kg/min). In the particular case of sand rats the RD was only 44% of that in Wistar rats having about the same body weight. 3. A 2.4-fold elevation of blood glucose above the basal level produces different increases of the RD: in rabbits 1.06-fold, in Wistar rats 1.5-fold and in sand rats 2.0-fold.
Schäfer
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Department of Experimental Diabetes Research, Central Institute of Diabetes Gerhardt Katsch, Karlsburg, GDR.
D000818:Animals; D003411:Arvicolinae; D001786:Blood Glucose / Q000502:physiology*; D001835:Body Weight / Q000502:physiology*; D005947:Glucose / Q000378:metabolism*; D011817:Rabbits; D051381:Rats; D011919:Rats, Inbred Strains
D001786:Blood Glucose; D005947:Glucose