[Behavior of magnetic particles of metallic iron in animals].
Intraperitoneal introduction of 5-8 mu ferromagnetic iron particles into mouse leads to their capsulation in the liver and preservation in the organism during no less than 1 month. We have observed activation of peroxide lipid oxidation during 3-4 days after the introduction of particles and a two-fold increase of the free iron content in the liver. Intraperitoneal introduction of ferromagnetic particles with diameter below 1 mu produced rapid death. Intravenous injection of 5-8 mu diameter ferromagnetic particles into rat resulted in their accumulation in the liver, lung and spleen, probably due to the absorption of the iron particles by macrophages. In two weeks these particles were transformed and vanished from the tissues.
Shabarchina
M M
MM
Tsapin
A I
AI
Malenkov
A G
AG
Vanin
A F
AF
D000818:Animals; D004578:Electron Spin Resonance Spectroscopy; D007501:Iron / Q000097:blood / Q000737:chemistry*; D015227:Lipid Peroxidation; D008099:Liver / Q000737:chemistry; D008168:Lung / Q000737:chemistry; D008280:Magnetics; D051379:Mice; D009206:Myocardium / Q000737:chemistry; D051381:Rats; D013154:Spleen / Q000737:chemistry
D007501:Iron
Povedenie magnitnykh chastits metallicheskogo zheleza v organizme zhivotnykh.