[Bone marrow transplantation for pediatric solid tumor].
Bone marrow transplantation permits the use of greatly intensified cytoreductive therapy for cancer. Since 1981, fifteen children with disseminated solid tumor were treated by this method (6 Nb1, 6 Lymphoma, 1 PNET, 1 Hb1, 1 YST.). Eight out of 15 (53%) have been alive and well 2-96 (median 45) months after BMT. Though toxicity is severe, high dose chemo-radiotherapy using BMT after reaching complete remission with well scheduled induction chemotherapy and surgery is concluded as a treatment of choice for pediatric malignant solid tumor in advanced stage.
Yokoyama
S
S
Department of Surgery, Tokai University, School of Medicine, Isehara, Japan.
Hirakawa
H
H
Tajima
T
T
Mitomi
T
T
Yabe
H
H
Yabe
M
M
Kato
S
S
D016026:Bone Marrow Transplantation; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000601:surgery*