3-D components of a biological neural network visualized in computer generated imagery. II. Macular neural network organization.
Computer-assisted reconstructions of small parts of the macular neural network show how the nerve terminals and receptive fields are organized in 3-dimensional space. This biological neural network is anatomically organized for parallel distributed processing of information. Processing appears to be more complex than in computer-based neural networks, because spatiotemporal factors figure into synaptic weighting. Serial reconstruction data show anatomical arrangements which suggest that 1) assemblies of cells analyse and distribute information with inbuilt redundancy, to improve reliability; 2) feedforward/feedback loops provide the capacity for presynaptic modulation of output during processing; 3) constrained randomness in connectivities contributes to adaptability; and 4) local variations in network complexity permit differing analyses of incoming signals to take place simultaneously. The last inference suggests that there may be segregation of information flow to central stations subserving particular functions.
Ross
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MD
NASA-Ames Research Center, Moffett Field, California.
Meyer
G
G
Lam
T
T
Cutler
L
L
Vaziri
P
P
D008267:Acoustic Maculae / Q000294:innervation*; D000818:Animals; D003196:Computer Graphics; D006198:Hair Cells, Auditory / Q000648:ultrastructure; D007091:Image Processing, Computer-Assisted; D008855:Microscopy, Electron, Scanning; D009411:Nerve Endings / Q000648:ultrastructure; D009415:Nerve Net / Q000648:ultrastructure; D012444:Saccule and Utricle / Q000294:innervation*