Neuroleptic malignant syndrome with renal and respiratory complications--a case report.
The neuroleptic malignant syndrome is an idiosyncratic reaction to neuroleptic therapy which sometimes can be fatal because of the various associated complications. We describe a schizophrenic patient who, after commencement of haloperidol, developed this reaction which was complicated by acute oliguric renal failure and aspiration pneumonia. It is mandatory that the patient is treated in a medical intensive care unit once the syndrome is recognised. The management of the neuroleptic malignant syndrome and its complications is discussed.
Liam
C K
CK
Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur.
Ong
S B
SB
D058186:Acute Kidney Injury / Q000150:complications*; D014150:Antipsychotic Agents / Q000009:adverse effects; D005260:Female; D006220:Haloperidol / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D009459:Neuroleptic Malignant Syndrome / Q000150:complications* / Q000209:etiology; D011015:Pneumonia, Aspiration / Q000150:complications*; D012559:Schizophrenia / Q000188:drug therapy*
D014150:Antipsychotic Agents; D006220:Haloperidol