Activity of Na-K-ATPase and Ca-Mg-ATPase in red blood cell membranes of lead-depleted rats.
Na-K-ATPase and Ca-Mg-ATPase activity of erythrocyte membranes from lead-depleted rats were determined. In P0 generation there was no difference in activity of Na-K-ATPase and Ca-Mg-ATPase between control and depletion rats. In contrast to this, in F1 generation lead-depleted rats showed reduced activity of both enzymes. Possibly, these changes of Na-K-ATPase and Ca-Mg-ATPase activity cause the reduction of the mean corpuscular cell volume (MCV) observed in former lead depletion studies.
Eder
K
K
Institut für Ernährungsphysiologie, Technische Universität München-Weihenstephan, Freising, Fed. Rep. of Germany.
Reichlmayr-Lais
A M
AM
Kirchgessner
M
M
D000818:Animals; D017301:Ca(2+) Mg(2+)-ATPase / Q000097:blood*; D000252:Calcium-Transporting ATPases / Q000097:blood*; D004032:Diet; D004910:Erythrocyte Membrane / Q000201:enzymology*; D005260:Female; D007854:Lead / Q000172:deficiency*; D051381:Rats; D011919:Rats, Inbred Strains; D000254:Sodium-Potassium-Exchanging ATPase / Q000097:blood*
D007854:Lead; D017301:Ca(2+) Mg(2+)-ATPase; D000252:Calcium-Transporting ATPases; D000254:Sodium-Potassium-Exchanging ATPase