title: [Uveitis, caused by Echo-11 virus].
abstract: Analysis of clinical manifestations of a total enteroviral infection with ECHO-11 virus-induced uveitis in 58 infants aged 2 weeks to 1.5 years has shown that uveitis develops on days 1-10 of the disease and is associated with a weak injection, endothelial edema, hyperemia and edema of the iris rapidly eventuating in destruction of the pigment lamina and fenestration. Posterior synechiae, pupil deformations, grave uveitis with hypotonia of 4-10 mm Hg are rapidly developing. A two-year follow-up has shown marked hemo- and hydrodynamic disorders, retarded growth of the involved eye, development of grave complications in 60 percent of patients. The most characteristic late complications were iridal fenestration, pseudocoloboma-type pupil deformation, formation of prelental films, often pigmented. The condition is associated with active production of virus-neutralizing antibodies in titers of 1:4 to 1:16384. No relationship between the clinical course and antibody titers was revealed.
authors.forename: S V
authors.initials: SV
authors.lastname: Umanskaia
authors.forename: L A
authors.initials: LA
authors.lastname: Katargina
authors.forename: S Z
authors.initials: SZ
authors.lastname: Mostinskii
authors.forename: G A
authors.initials: GA
authors.lastname: Koroleva
authors.forename: G G
authors.initials: GG
authors.lastname: Pecheritsa
authors.forename: I P
authors.initials: IP
authors.lastname: Novikova
mesh_terms: D000917:Antibody Formation; D004457:Echovirus Infections / Q000503:physiopathology*; D015828:Eye Infections, Viral / Q000503:physiopathology*; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D014605:Uveitis / Q000382:microbiology* / Q000503:physiopathology
vernacular_title: Uveit, vyzvannyĭ virusom Echo-11.