title: Ornithine decarboxylase induction and DNA damage as a predictive assay for potential carcinogenicity.
authors.forename: K T
authors.initials: KT
authors.lastname: Kitchin
authors.forename: J L
authors.initials: JL
authors.lastname: Brown
authors.forename: A P
authors.initials: AP
authors.lastname: Kulkarni
mesh_terms: D000410:Alanine Transaminase / Q000378:metabolism; D000818:Animals; D015197:Carcinogenicity Tests; D002273:Carcinogens / Q000633:toxicity*; D003372:Coumaphos / Q000494:pharmacology; D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis; D004249:DNA Damage; D003633:Dichlorodiphenyl Dichloroethylene / Q000633:toxicity*; D004790:Enzyme Induction; D005260:Female; D005978:Glutathione / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000201:enzymology / Q000473:pathology*; D008113:Liver Neoplasms / Q000139:chemically induced* / Q000473:pathology; D009955:Ornithine Decarboxylase / Q000096:biosynthesis*; D011407:Propane / Q000031:analogs & derivatives* / Q000633:toxicity; D051381:Rats; D011919:Rats, Inbred Strains; D014144:Tragacanth / Q000494:pharmacology
chemical_list: D002273:Carcinogens; D003633:Dichlorodiphenyl Dichloroethylene; D014144:Tragacanth; D003577:Cytochrome P-450 Enzyme System; C007318:1,2-dibromo-3-chloropropane; D000410:Alanine Transaminase; D009955:Ornithine Decarboxylase; D005978:Glutathione; D003372:Coumaphos; D011407:Propane