title: Bone marrow cell populations mimicking common acute lymphoblastic leukemia in infants with stage IV-S neuroblastoma.
abstract: Immunophenotyping of bone marrow mononuclear cells of 2 infants with stage IV-S neuroblastoma revealed the presence of many lymphoblasts and immature lymphocytes. Immunophenotyping showed that a high percentage of bone marrow cells were positive for the HLA-DR, CD19, CD20 and CD10 phenotype, similar to common acute lymphoblastic leukemia cells. Within 6 months of follow-up, without any treatment, complete regression of the tumors was observed. The coexistence of these two unusual populations will be discussed.
authors.affiliation: Institute of Hematology, Chaim Sheba Medical Center, Tel Hashomer, Israel.
authors.forename: M
authors.initials: M
authors.lastname: Mandel
authors.forename: G
authors.initials: G
authors.lastname: Rechavi
authors.forename: Y
authors.initials: Y
authors.lastname: Neumann
authors.forename: M
authors.initials: M
authors.lastname: Biniaminov
authors.forename: F
authors.initials: F
authors.lastname: Brok-Simoni
authors.forename: Y
authors.initials: Y
authors.lastname: Bojanover
authors.forename: Y
authors.initials: Y
authors.lastname: Burstein
authors.forename: I
authors.initials: I
authors.lastname: Ben-Bassat
authors.forename: B
authors.initials: B
authors.lastname: Ramot
mesh_terms: D001853:Bone Marrow / Q000276:immunology / Q000473:pathology*; D006801:Humans; D016130:Immunophenotyping; D007223:Infant; D008214:Lymphocytes / Q000276:immunology / Q000473:pathology; D008297:Male; D009447:Neuroblastoma / Q000473:pathology*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000473:pathology*