[Localization of human testis determining factors on Y chromosome].
This is a study of in situ chromosomal hybridization and dot blot and southern blot hybridization using a testis determining factor related probe Y156 in sexually malformed patients. According to the phenotype karyotype analysis and hybridization results of these cases, especially 2 cases with dic (Y) and different breakpoints, we consider that the TDF must be located on YP11.32. The clinical value of Y156 probe is discussed.
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D015342:DNA Probes; D004268:DNA-Binding Proteins / Q000032:analysis / Q000235:genetics*; D012734:Disorders of Sex Development / Q000175:diagnosis; D006801:Humans; D051741:Kruppel-Like Transcription Factors; D008297:Male; D009693:Nucleic Acid Hybridization; D012729:Sex Chromosome Aberrations / Q000175:diagnosis; D014157:Transcription Factors; D014998:Y Chromosome
D015342:DNA Probes; D004268:DNA-Binding Proteins; D051741:Kruppel-Like Transcription Factors; D014157:Transcription Factors; C054430:ZFY protein, human