title: Squamous and basal cell cancers directly invading major salivary glands.
abstract: Epidermoid carcinoma of the skin of the head and neck may uncommonly involve the parotid gland by either direct extension or metastases to the parotid lymph nodes. The parotid gland contains a rich network of superficial and deep nodes, draining a large area of the facial region, with the preauricular, cheek, ear, and eyelid dominating. Few patients with direct parenchymal invasion of the parotid gland by a simultaneously existing squamous or basal cell carcinoma were reported. We could find no report discussing direct tumoral invasion into the submandibular salivary gland. Three patients with squamous cell carcinomas and 2 with basal cell carcinomas of the skin directly involving the underlying salivary glands are presented. The few authors discussing this subject concur that treatment should include resection of the primary tumor along with parotidectomy. Elective neck dissection and irradiation are proposed. The course of disease, treatment, and survival of our patients are discussed.
authors.affiliation: Department of Otolaryngology, Hasharon Hospital, Golda Medical Center, Petah Tikvah, Israel.
authors.forename: Y P
authors.initials: YP
authors.lastname: Talmi
authors.forename: R
authors.initials: R
authors.lastname: Gal
authors.forename: Y
authors.initials: Y
authors.lastname: Finkelstein
authors.forename: M
authors.initials: M
authors.lastname: Nobel
authors.forename: I
authors.initials: I
authors.lastname: Shvilli
authors.forename: Y
authors.initials: Y
authors.lastname: Zohar
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002280:Basal Cell Carcinoma / Q000556:secondary / Q000601:surgery*; D002294:Carcinoma, Squamous Cell / Q000556:secondary / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012468:Salivary Gland Neoplasms / Q000556:secondary / Q000601:surgery*; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*