title: Validation of single-photon emission computed tomography (SPECT) using thallium-201 in patients with lung cancer.
abstract: To evaluate the primary site, pulmonary hilar, and mediastinal lesions in patients with lung cancer, thallium-201 using single-photon emission computed tomography (SPECT) was used as a tumor agent. The study population consisted of 7 patients (5 men and 2 women), aged 57 to 82 years (mean 68). Tl-201 tomography imaged positive at the primary site in all patients with lung cancer. The images demonstrated the tumor and/or mediastinal lymph nodes that were greater than 2.0cm. In particular, each tomograms facilitated the identification of the Tl-201 increased uptake in proportion to primary site. The short waiting period after injection with Tl-201 clearly offers a major advantage over alternative tumor imaging agents, such as Ga-67 or radiolabeled monoclonal antibodies. Furthermore, Tl-201 SPECT may be useful to detect the tumor and/or mediastinal lymph nodes in patients with lung cancer.
authors.affiliation: Department of Radiology, Kurume University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Ishibashi
authors.forename: N
authors.initials: N
authors.lastname: Honda
authors.forename: F
authors.initials: F
authors.lastname: Yoshioka
authors.forename: T
authors.initials: T
authors.lastname: Yoshii
authors.forename: Y
authors.initials: Y
authors.lastname: Nomura
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
authors.forename: O
authors.initials: O
authors.lastname: Nagayasu
authors.forename: M
authors.initials: M
authors.lastname: Sato
authors.forename: K
authors.initials: K
authors.lastname: Fujimoto
authors.forename: N
authors.initials: N
authors.lastname: Umezaki
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D013794:Thallium Radioisotopes