title: Metabolism of 17 beta-estradiol by oral Streptococcus mutans, Streptococcus sanguis, Bacillus cereus and Candida albicans.
abstract: The ability of oral isolates of Streptococcus mutans, Streptococcus sanguis, Bacillus cereus and Candida albicans to metabolize 17 beta-estradiol was analyzed by thin-layer chromatography using 4-14C-estradiol as the substrate. All test microorganisms metabolized 17 beta-estradiol. Estrone was the main metabolic product, except for B. cereus, which converted 17 beta-estradiol mainly to unidentified, more polar metabolites. S. sanguis and B. cereus had the most active metabolism but S. mutans and C. albicans were also active.
authors.affiliation: Department of Physiology, University of Turku, Finland.
authors.forename: A
authors.initials: A
authors.lastname: Ojanotko-Harri
authors.forename: M
authors.initials: M
authors.lastname: Laine
authors.forename: J
authors.initials: J
authors.lastname: Tenovuo
mesh_terms: D001409:Bacillus cereus / Q000378:metabolism; D002176:Candida albicans / Q000378:metabolism; D002855:Chromatography, Thin Layer; D004958:Estradiol / Q000378:metabolism*; D004970:Estrone; D013295:Streptococcus mutans / Q000378:metabolism*; D013298:Streptococcus sanguis / Q000378:metabolism
chemical_list: D004970:Estrone; D004958:Estradiol