title: [Malignant T-cell neoplasia during treatment with azathioprine and prednisone after kidney transplantation].
abstract: Patients receiving immunosuppressive treatment show an increased incidence of malignant lymphoproliferative disease, mainly in the form of B-lymphomata, on account of constant antigen stimulation from an implanted organ and/or impaired immunological defense which permit cells which have undergone mutation or have been transformed by viruses to proliferate. Malignant T-proliferative disease is rare in this patient category. The authors present a case in which a man treated with azathioprin and prednisone who had been well and without symptoms of rejection during a total of seven years after renal transplantation, which suggests that the T-cell neoplasia was due to the immunosuppressive treatment.
authors.affiliation: Medicinsk afdeling C., Aalborg Sygehus.
authors.forename: L L
authors.initials: LL
authors.lastname: Olesen
authors.forename: L
authors.initials: L
authors.lastname: Mølby
mesh_terms: D001379:Azathioprine / Q000009:adverse effects*; D006801:Humans; D016030:Kidney Transplantation / Q000276:immunology*; D016399:Lymphoma, T-Cell / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000009:adverse effects*; D013997:Time Factors
chemical_list: D001379:Azathioprine; D011241:Prednisone
vernacular_title: Malign T-celle neoplasi under azatioprin- og prednisonbehandling efter nyretransplantation.