title: Pressing and stretching of psoriatic lesions induces their involution.
abstract: Remission of psoriatic lesions was induced when the lesions were firmly pressed with a plastic cap held in place by an elastic bandage for 24 h or stretched with a negative pressure of 200 mmHg for 2 h. Seven out of 10 patients showed a clinical improvement of the treated psoriatic lesions. These lesions cleared within 1-3 weeks after removal of the apparatus. Biopsy specimens taken from responding lesions showed a reduction in psoriatic epidermal and dermal changes as compared with those taken before treatment. Patients having extensive active psoriatic lesions experienced recurrence after approx. 3 weeks. No complications were seen except for an occasional formation of erosions at sites the edges of the apparatuses were apposed too firmly.
authors.affiliation: Department of Dermatology, Tohoku University School of Medicine, Sendai, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Takematsu
authors.forename: H
authors.initials: H
authors.lastname: Tagami
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011312:Pressure; D011565:Psoriasis / Q000473:pathology / Q000628:therapy*; D012008:Recurrence