Estimates of quantitative genetic parameters of immunological traits in the chicken.
Three in vivo assays were used to measure the immunocompetence of chickens in two generations of a selection experiment. The obtained data were used to estimate the variance components for sire and dam for antibody production to Pasteurella multocida and Mycoplasma gallisepticum vaccines, for T-cell-mediated immunity evaluated by a phytohemagglutinin wing web assay, and for clearance of foreign particles from the circulatory system. Heritabilities of and genetic correlations among these immunological traits were calculated from the sire variance components. Heritability estimates of the immunological traits based on the sire component of variance ranged from .06 to .53, and genetic correlations among immunological traits were generally negative.
Cheng
S
S
Department of Animal Science, Iowa State University, Ames 50011.
Rothschild
M F
MF
Lamont
S J
SJ
D000704:Analysis of Variance; D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis; D001428:Bacterial Vaccines / Q000276:immunology; D001947:Breeding; D002645:Chickens / Q000235:genetics* / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D014644:Genetic Variation; D007111:Immunity, Cellular / Q000235:genetics; D007121:Immunocompetence / Q000235:genetics*; D009174:Mycoplasma / Q000276:immunology; D016979:Pasteurella multocida / Q000276:immunology; D010587:Phagocytosis; D012044:Regression Analysis; D013601:T-Lymphocytes / Q000276:immunology
D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines