title: Adverse reaction to pomegranate ingestion.
abstract: We present a non-atopic 85-year-old woman, with a late-onset recidivant tongue angio-edema due to pomegranate intake, as proven by a double blind oral challenge test. This is the first case ever reported about adverse reaction to pomegranate. We have been unable to demonstrate an IgE-mediated mechanism (prick test, histamine release test and RAST with pomegranate were all negative). We emphasize the importance of clinical history and oral challenge test in the diagnosis of food allergy.
authors.affiliation: Allergy Service, Hospital Ramon y Cajal, Madrid, Spain.
authors.forename: J M
authors.initials: JM
authors.lastname: Igea
authors.forename: J
authors.initials: J
authors.lastname: Cuesta
authors.forename: M
authors.initials: M
authors.lastname: Cuevas
authors.forename: L M
authors.initials: LM
authors.lastname: Elias
authors.forename: C
authors.initials: C
authors.lastname: Marcos
authors.forename: M
authors.initials: M
authors.lastname: Lazaro
authors.forename: J A
authors.initials: JA
authors.lastname: Compaired
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000799:Angioedema / Q000175:diagnosis / Q000209:etiology; D005260:Female; D005512:Food Hypersensitivity / Q000175:diagnosis / Q000209:etiology*; D005638:Fruit / Q000009:adverse effects*; D006801:Humans