title: The use of hair analysis to document a cocaine overdose following a sustained survival period before death.
abstract: Hair analysis for cocaine was used in the investigation of a case of accidental cocaine poisoning. A 25-year-old man consumed an entire bottle of Pony Malta, an imported Colombian soft drink. Unbeknownst to him, the 6.2-oz bottle contained a large quantity of cocaine. It was subsequently discovered that this bottle was one of 45 recovered that contained cocaine as part of a smuggling scheme. The subject was hospitalized for acute cocaine intoxication but died 24 days later. The admission blood contained 2.3 mg/L of cocaine and 4.5 mg/L of benzoylecgonine. Subsequent segmental analysis by MS/MS of hair samples taken at the autopsy revealed a peak cocaine concentration in the segment corresponding to the time he ingested the tainted beverage. The use of hair analysis as an adjunct to traditional analytical techniques may help document drug use history and is especially useful in situations have blood and urine specimens have not been collected in a timely fashion.
authors.affiliation: Chemistry/Toxicology Unit, Federal Bureau of Investigation, Washington, D.C.
authors.forename: R
authors.initials: R
authors.lastname: Martz
authors.forename: B
authors.initials: B
authors.lastname: Donnelly
authors.forename: D
authors.initials: D
authors.lastname: Fetterolf
authors.forename: L
authors.initials: L
authors.lastname: Lasswell
authors.forename: G W
authors.initials: GW
authors.lastname: Hime
authors.forename: W L
authors.initials: WL
authors.lastname: Hearn
mesh_terms: D000328:Adult; D003042:Cocaine / Q000032:analysis / Q000506:poisoning*; D062787:Drug Overdose / Q000175:diagnosis; D005506:Food Contamination; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006197:Hair / Q000737:chemistry*; D006801:Humans; D008297:Male
chemical_list: D003042:Cocaine