title: [Chemotherapeutic pathomorphosis of breast cancer].
abstract: Features of pathomorphism of mammary carcinoma were studied in 177 women after a course of drug therapy. Qualitative and quantitative morphologic changes in the tumor were poorly manifest: they were detected in only 54 percent of patients and only in 9 percent the effect was manifest (third-fourth stage of involvement). Characteristic findings here were augmentation of cellular dystrophy, necrotic changes, enhanced nuclear polymorphism; significant injury to tumor parenchyma was paralleled by development of xanthomatosis foci and lymphoid histiocytic infiltration.
authors.forename: G A
authors.initials: GA
authors.lastname: Frank
authors.forename: N N
authors.initials: NN
authors.lastname: Volchenko
authors.forename: V I
authors.initials: VI
authors.lastname: Borisov
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D002277:Carcinoma / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D002945:Cisplatin / Q000627:therapeutic use; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006801:Humans; D008197:Lymph Node Excision; D015409:Mastectomy, Radical; D008727:Methotrexate / Q000627:therapeutic use; D008938:Mitosis; D009336:Necrosis; D011110:Polymorphism, Genetic
chemical_list: D002945:Cisplatin; D005472:Fluorouracil; D008727:Methotrexate
vernacular_title: Khimioterapevticheskiĭ patomorfoz raka molochnoĭ zhelezy.