title: Expression of prognostic factors (EGFR, ER) by immunohistochemical staining method in male breast cancer.
abstract: Twelve male patients with operable breast cancer were evaluated for the expression of prognostic factors by immunohistochemical staining assay. Seven patients were stage I & II, and five patients were stage III. Axillary lymph node positivity was 42%. Nine patients were nuclear grade I, three were nuclear grade II, and none were nuclear grade III. The expression rate of EGFR (epidermal growth factor receptor), ER (estrogen receptor) were 8.3%, 70.0% respectively. This limited data suggest better tumor behavior in male than in female breast cancer. Adjuvant treatment should be considered in male breast cancer just as in females, based on axillary lymph node and ER states.
authors.affiliation: Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: H C
authors.initials: HC
authors.lastname: Chung
authors.forename: D L
authors.initials: DL
authors.lastname: Kim
authors.forename: E H
authors.initials: EH
authors.lastname: Koh
authors.forename: J H
authors.initials: JH
authors.lastname: Kim
authors.forename: J K
authors.initials: JK
authors.lastname: Roh
authors.forename: J S
authors.initials: JS
authors.lastname: Min
authors.forename: K S
authors.initials: KS
authors.lastname: Lee
authors.forename: W I
authors.initials: WI
authors.lastname: Yang
authors.forename: B S
authors.initials: BS
authors.lastname: Kim
authors.forename: K B
authors.initials: KB
authors.lastname: Lee
mesh_terms: D001943:Breast Neoplasms / Q000737:chemistry* / Q000473:pathology; D002277:Carcinoma / Q000737:chemistry* / Q000473:pathology; D066246:ErbB Receptors / Q000032:analysis*; D006801:Humans; D007150:Immunohistochemistry; D008207:Lymphatic Metastasis; D008297:Male; D009367:Neoplasm Staging; D011379:Prognosis; D011960:Receptors, Estrogen / Q000032:analysis*
chemical_list: D011960:Receptors, Estrogen; D066246:ErbB Receptors