[The membrane-bound calcium of the thrombocytes in essential hypertension].
The investigation was aimed at analyzing membrane-bound calcium in platelets of patients with essential hypertension (EH) and of healthy persons. 55 men were examined. Of these, 38 presented with EH and 17 were healthy. Membrane-bound calcium determined with the help of the chlortetracycline fluorescent probe. The level of membrane-bound calcium in intracellular compartments was higher in patients with EH than in the control. The kinetic curves of the binding of the chlortetracycline fluorescent probe with cellular membranes allow one to reveal disturbances of calcium-dependent membrane processes in persons suffering from EH.
Churin
K V
KV
Ianushkene
T S
TS
Kuznetsov
S R
SR
D000328:Adult; D001792:Blood Platelets / Q000378:metabolism*; D002118:Calcium / Q000097:blood*; D002451:Cell Compartmentation / Q000502:physiology; D002462:Cell Membrane / Q000378:metabolism; D002751:Chlortetracycline; D002908:Chronic Disease; D005456:Fluorescent Dyes; D006801:Humans; D006973:Hypertension / Q000097:blood; D008875:Middle Aged
D005456:Fluorescent Dyes; D002118:Calcium; D002751:Chlortetracycline
Membranno-sviazannyĭ kal'tsiĭ trombotsitov pri éssentsial'noĭ gipertenzii.