title: Tracheo-bronchitis as a complication of Crohn's disease--a case report.
abstract: A case of Crohn's enterocolitis associated with diffuse tracheo-bronchitis is presented herein. Although respiratory tract involvement in Crohn's disease is extremely rare, our review of the world literature revealed several common clinical pathologic features. These features include a productive cough with chest X-ray films which are normal except for some peripheral involvement. Bronchoscopy, however, shows diffuse inflammation of the trachea and bronchi with widely scattered whitish lesions while biopsy reveals a granulomatous infiltration of inflammatory cells. This tracheobronchitis typically responds well to treatment with prednisone.
authors.affiliation: Research Center for Polyposis and Intestinal Diseases, Tokyo Medical and Dental University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Iwama
authors.forename: T
authors.initials: T
authors.lastname: Higuchi
authors.forename: M
authors.initials: M
authors.lastname: Imajo
authors.forename: S
authors.initials: S
authors.lastname: Akagawa
authors.forename: O
authors.initials: O
authors.lastname: Matsubara
authors.forename: Y
authors.initials: Y
authors.lastname: Mishima
mesh_terms: D000328:Adult; D001980:Bronchi / Q000473:pathology; D001991:Bronchitis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D001999:Bronchoscopy; D003424:Crohn Disease / Q000150:complications*; D006801:Humans; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D014132:Trachea / Q000473:pathology; D014136:Tracheitis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology
chemical_list: D011241:Prednisone