Nucleotide sequence and intracellular location of the product of the fosfomycin resistance gene from transposon Tn2921.
An 863-base-pair DNA fragment containing the fosfomycin resistance gene from transposon Tn2921 was sequenced. Analysis of the sequence revealed the presence of a single open reading frame that encoded the FOS polypeptide of 16 kilodaltons from Tn2921. Minicell fractionation studies showed that the FOS protein was located in the bacterial cytoplasm.
Navas
J
J
Departamento de Biología Molecular, Facultad de Medicina, Universidad de Cantabria, Santander, Spain.
León
J
J
Arroyo
M
M
García Lobo
J M
JM
D001483:Base Sequence; D003062:Codon; D003593:Cytoplasm / Q000378:metabolism; D004251:DNA Transposable Elements / Q000187:drug effects*; D004352:Drug Resistance, Microbial; D004926:Escherichia coli; D005578:Fosfomycin / Q000494:pharmacology*; D005798:Genes, Bacterial; D008969:Molecular Sequence Data; D010957:Plasmids
D003062:Codon; D004251:DNA Transposable Elements; D005578:Fosfomycin