title: Morphine impurity with opioid activity is identified as 10 alpha-hydroxymorphine.
authors.affiliation: Department of Pharmacy, School of Pharmacy, University of California, San Francisco 94143.
authors.forename: H
authors.initials: H
authors.lastname: Farsam
authors.forename: S
authors.initials: S
authors.lastname: Eiger
authors.forename: J
authors.initials: J
authors.lastname: Lameh
authors.forename: A
authors.initials: A
authors.lastname: Rezvani
authors.forename: B W
authors.initials: BW
authors.lastname: Gibson
authors.forename: W
authors.initials: W
authors.lastname: Sadée
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D004340:Drug Contamination; D006168:Guinea Pigs; D066298:In Vitro Techniques; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D009020:Morphine / Q000032:analysis*; D009022:Morphine Derivatives / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology; D009119:Muscle Contraction / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects; D010084:Oxidation-Reduction; D011957:Receptors, Opioid / Q000187:drug effects; D013056:Spectrophotometry, Ultraviolet
chemical_list: D009022:Morphine Derivatives; D011957:Receptors, Opioid; C067700:10-hydroxymorphine; D009020:Morphine