Medical response to nuclear and radiation accidents.
The authors discuss the several strategies for treating bone marrow suppression caused by exposure to acute high-dose total body radiation. Supportive measures prevent death from infection and/or bleeding and thereby permit autologous bone marrow recovery. Another approach stimulates bone marrow recovery using molecularly cloned hematopoietic growth factors. A third approach replaces the damaged bone marrow via a transplant, either permanently or temporarily.
Gale
R P
RP
Department of Medicine, School of Medicine, University of California, Los Angeles.
Butturini
A
A
D000059:Accidents; D000818:Animals; D016026:Bone Marrow Transplantation; D006801:Humans; D009688:Nuclear Reactors; D016273:Occupational Exposure; D011829:Radiation Dosage; D011832:Radiation Injuries / Q000150:complications / Q000628:therapy*