[Studies on the location of eight lectins in breast carcinoma].
100 cases of breast carcinoma were studied with lectin affinitive histochemistry technology. The result showed that Ricinus comunis agglutinin (RCA1) was located in almost all intraductal carcinomas but one, while the positive rates in the other types were obviously low (P less than 0.05). The positive rate of Ulex europaeus agglutinin-I (UEA1) in well-differentiated types was higher than that in poorly-differentiated ones (P less than 0.05). The location of Peanut agglutinin (PNA), Bandeiraea Simplicifolia (BSL) and UEA1 in breast carcinomas exhibited some regularity and it might be useful in understanding the differentiation of breast carcinomas. No relationship between changes of the eight lectins and metastases in axillary lymph nodes was observed, but the authors considered that PNA-affinitive histochemistry was beneficial to the detection of micrometastases in lymph nodes.
Zheng
Z
Z
Department of Pathology, Sun Yat-sen University of Medical Sciences, Kuang zhou.
Ji
Z M
ZM
D001943:Breast Neoplasms / Q000378:metabolism* / Q000473:pathology; D002277:Carcinoma / Q000378:metabolism / Q000473:pathology; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000378:metabolism* / Q000473:pathology; D002367:Ricinus communis; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D037102:Lectins / Q000032:analysis*; D008198:Lymph Nodes / Q000378:metabolism; D008207:Lymphatic Metastasis; D037121:Plant Lectins; D010947:Plants, Toxic
D037102:Lectins; D037121:Plant Lectins; C017707:Ricinus communis agglutinin-1; C036850:Ulex europaeus lectins