title: Insulin resistance in the elderly.
abstract: The two-step hyperinsulinemic euglycemic clamp technique in young and aged adults demonstrated that insulin resistance observed in the elderly was due to a small reduction in pancreatic insulin output together with a small reduction in peripheral tissue response to insulin.
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology*; D005947:Glucose / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000502:physiology*; D007333:Insulin Resistance / Q000502:physiology*; D010179:Pancreas / Q000502:physiology*
chemical_list: D007328:Insulin; D005947:Glucose