title: [Study of gastric APUD cells in gastroduodenal hemorrhage].
abstract: It was found that in patients with gastroduodenal hemorrhage the number of serotonin-, histamine-, and melatonin-producing apudocytes in the gastric mucosa increases while the number of cells producing gastrin, adrenaline, and noradrenaline reduces. In timely arrest of hemorrhage, the primarily increased number of melatonin-producing apudocytes diminishes with time from the onset of bleeding and reaches normal values gradually. The essential differences in the content of melatonin- and noradrenaline- producing apudocytes in patients with and without hemorrhage allow this morphological sign to be used as diagnostic and prognostic criteria in gastroduodenal hemorrhages.
authors.forename: G L
authors.initials: GL
authors.lastname: Ratner
authors.forename: I M
authors.initials: IM
authors.lastname: Kvetnoĭ
authors.forename: M I
authors.initials: MI
authors.lastname: Bereslavskiĭ
authors.forename: Ia M
authors.initials: IaM
authors.lastname: Margolis
authors.forename: B L
authors.initials: BL
authors.lastname: Vaĭsman
mesh_terms: D001078:APUD Cells / Q000378:metabolism / Q000473:pathology*; D000328:Adult; D000368:Aged; D002395:Catecholamines / Q000096:biosynthesis; D002452:Cell Count; D004381:Duodenal Ulcer / Q000150:complications* / Q000473:pathology; D005260:Female; D005755:Gastrins / Q000378:metabolism; D006729:Hormones, Ectopic / Q000378:metabolism; D006801:Humans; D008297:Male; D008550:Melatonin / Q000378:metabolism; D008875:Middle Aged; D010438:Peptic Ulcer Hemorrhage / Q000473:pathology*; D011706:Pyloric Antrum / Q000473:pathology*; D013276:Stomach Ulcer / Q000150:complications* / Q000473:pathology
chemical_list: D002395:Catecholamines; D005755:Gastrins; D006729:Hormones, Ectopic; D008550:Melatonin
vernacular_title: Izuchenie apudotsitov zheludka pri gastroduodenal'nykh krovotecheniiakh.