Failure to reproduce increased calcium uptake in human lymphocytes at purported cyclotron resonance exposure conditions.
An attempt was made to verify a report (Liboff et al. 1987) that a unique combination of DC and AC magnetic field exposures at room temperature results in a 3-fold increase in 45Ca2+ uptake by human lymphocytes in vitro. Exposures at "resonance condition", as well as at frequencies and amplitudes above and below the reported effective exposure conditions, were without effect, as were exposures at 37 degrees C. Treatment with ionomycin (0.25 microM), a positive control, resulted in a highly significant increase 45Ca2+ uptake. Some experiments were performed simultaneously by different investigators. Their results did not differ significantly. All experiments were conducted "double blindly".
Prasad
A V
AV
Department of Biophysics, School of Medicine and Dentistry, University of Rochester, NY 14642.
Miller
M W
MW
Carstensen
E L
EL
Cox
C
C
Azadniv
M
M
Brayman
A A
AA
D000704:Analysis of Variance; D002118:Calcium / Q000378:metabolism*; D002478:Cells, Cultured; D006801:Humans; D015759:Ionomycin / Q000494:pharmacology; D008214:Lymphocytes / Q000378:metabolism*; D008280:Magnetics
D015759:Ionomycin; D002118:Calcium