title: [Chemotherapy in metastasizing prostate carcinoma].
abstract: Seventeen patients with metastasized hormone-resistant prostate cancer were treated between January 1986 and October 1989 with combination chemotherapy at the Department of Urology, University of Würzburg Medical School. In 1 of the 17 patients a complete remission lasting 4 months was observed. In 3 patients a partial remission was noted, and in 5 others stable disease for an average of 6.8 months occurred. Tumor progression was seen in 7 patients. In all 16 evaluable cases palliation of tumor pain was achieved with this kind of treatment. The role of chemotherapy in the treatment of metastasized prostate cancer is discussed.
authors.affiliation: Urologische Klinik und Poliklinik, Universität Würzburg.
authors.forename: D
authors.initials: D
authors.lastname: Heimbach
authors.forename: M
authors.initials: M
authors.lastname: Wirth
authors.forename: H
authors.initials: H
authors.lastname: Frohmüller
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D011471:Prostatic Neoplasms / Q000188:drug therapy* / Q000401:mortality; D016019:Survival Analysis
chemical_list: D000970:Antineoplastic Agents; D005047:Etoposide; D004317:Doxorubicin; D003520:Cyclophosphamide; D002945:Cisplatin; D008727:Methotrexate
vernacular_title: Chemotherapie beim metastasierten Prostatakarzinom.