[Comparative analysis of genomes of oncogenic B-lymphotropic herpesviruses reproducing in cell lines obtained from different monkey species].
The aim of this work was to study genomes of B-lymphotropic oncogenic herpesviruses of Macaca arctoides (HVMA), Papio hamadryas (HVP) and Cercopithecus aethiops (HVGM). Blot-hybridization detected inter- and intraspecific genome heterogeneity of investigated viruses in restriction sites EcoR1, Pst1 and Hind111. Virus-specific sequences in two-cell lines obtained from HVMA-induced rabbit tumours can prove HVMA a role in malignant tumour induction in rabbits.
Kakubava
V V
VV
Lapin
B A
BA
Timanovskaia
V V
VV
Agrba
V Z
VZ
Novozhilov
S V
SV
Semenova
S V
SV
D000818:Animals; D015139:Blotting, Southern; D002460:Cell Line; D002522:Chlorocebus aethiops; D004279:DNA, Viral / Q000032:analysis; D005814:Genes, Viral; D015654:Herpesvirus 6, Human / Q000235:genetics* / Q000254:growth & development / Q000302:isolation & purification; D008251:Macaca; D009858:Oncogenic Viruses / Q000235:genetics*; D010215:Papio; D015183:Restriction Mapping
D004279:DNA, Viral
Sravnitel'nyĭ analiz genomov onkogennykh B-limfotropnykh virusov gerpesa, reprodutsiruiushchikhsia v kletochnykh liniiakh, poluchennykh ot obez'ian razlichnykh vidov.