title: IL9 maps to mouse chromosome 13 and human chromosome 5.
abstract: Mouse and human cDNA clones encoding the T-cell and mast cell growth factor P40, now designated IL-9, were used to identify DNA restriction fragment length polymorphisms (RFLPs) in sets of somatic cell hybrids and between inbred strains of mice and interspecific backcross progeny. Segregation of mouse and human chromosomes among somatic cell hybrids indicated a location on mouse chromosome 13 and human chromosome 5. RFLPs were identified among inbred strains of mice. Analysis of chromosome 13 alleles for Tcrg, Dhfr, and Il-9 in an interspecific cross between Mus musculus and NFS/N or C58/J mice indicates that IL9 is distal to Tcrg and proximal to Dhfr.
authors.affiliation: Laboratory of Genetics, National Cancer Institute, Bethesda, MD 20892.
authors.forename: B A
authors.initials: BA
authors.lastname: Mock
authors.forename: M
authors.initials: M
authors.lastname: Krall
authors.forename: C A
authors.initials: CA
authors.lastname: Kozak
authors.forename: M N
authors.initials: MN
authors.lastname: Nesbitt
authors.forename: O W
authors.initials: OW
authors.lastname: McBride
authors.forename: J C
authors.initials: JC
authors.lastname: Renauld
authors.forename: J
authors.initials: J
authors.lastname: Van Snick
mesh_terms: D000483:Alleles; D000818:Animals; D015139:Blotting, Southern; D002875:Chromosomes; D003001:Cloning, Molecular; D006023:Glycoproteins / Q000235:genetics*; D006133:Growth Substances / Q000235:genetics*; D006801:Humans; D016906:Interleukin-9; D051379:Mice; D008815:Mice, Inbred Strains / Q000235:genetics; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D006023:Glycoproteins; D006133:Growth Substances; D016906:Interleukin-9