Euthyroid thyrotoxic periodic paralysis.
Thyrotoxic periodic paralysis (TPP) is a dramatic complication of thyrotoxicosis usually seen in young men with untreated Graves' disease. We report the case of a 29-year-old active duty man with TPP attacks atypical in that they occurred during and after resolution of the hyperthyroidism. Our literature review revealed only two previously reported cases of TPP concurrent with euthyroidism. Risk factors for TPP include the postprandial state after carbohydrate-rich meals and the post-exertional state. At least a 2-week "window of vulnerability" for TPP appears to exist after initiation of antithyroid therapy. Hyperthyroid active duty males are especially at risk of TPP, and require physical profiling at the time of diagnosis and for a limited period after they become euthyroid, to minimize the occurrence of this complication.
Rone
J K
JK
Department of Internal Medicine, USAF Medical Center Keesler, Biloxi, MS 39534.
Brietzke
S A
SA
D000328:Adult; D006111:Graves Disease / Q000097:blood / Q000150:complications / Q000188:drug therapy; D006801:Humans; D008297:Male; D010243:Paralysis / Q000209:etiology*; D013963:Thyroid Hormones / Q000097:blood*; D013971:Thyrotoxicosis / Q000150:complications* / Q000188:drug therapy / Q000209:etiology
D013963:Thyroid Hormones