[Mechanism of cytogenetic adaptive response induced by low dose radiation].
Cytogenetic observation on human lymphocytes indicated that pre-exposure of 10, 50 and 75 mGy X-rays could induced the adaptive response. Experimental results with different temperature treatment showed that the adaptive response induced by low dose radiation could be enhanced by 41 degrees C and 43 degrees C, but inhibited by 4 degrees C in addition the treatment by 41 degrees C for one hour could also cause the adaptive response as did low dose radiation. Results showed that adaptive response induced by low dose radiation (10 or 50 mGy X-rays) could be eliminated by the protein synthesis inhibitor, implying that the adaptive response is related with the metabolism of cells, especially with the production of certain protective proteins.
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D000222:Adaptation, Physiological / Q000528:radiation effects*; D000818:Animals; D002869:Chromosome Aberrations; D004260:DNA Repair; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006801:Humans; D008214:Lymphocytes / Q000528:radiation effects; D008297:Male; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000235:genetics; D013696:Temperature