title: Testicular cancer in young men and parental occupational exposure.
abstract: To investigate whether parental occupation, especially during the 12 month period before birth, could be responsible for elevated rates of testicular cancer in young men, we used data from a case-control study of 223 cases and 212 controls conducted in the Washington, DC area. For all histologic types of testicular cancer combined, no significant associations were found for specific occupations, nor for the broad occupational categories of professional, other white collar, or blue collar workers. However, for cases with seminomas, excess risks were seen for those with parents employed in the following occupations: mothers in health-related occupations, O.R. = 4.6 (1.1-19.1), and fathers working in automobile service stations, O.R. = 4.0 (0.6-24.5), manufacturing industries, O.R. = 2.2 (1.0-4.2), and aircraft production and maintenance, O.R. = 5.3 (0.7-24.1). Although these findings for seminoma are intriguing, they do not explain the increase of testicular cancer in young men.
authors.affiliation: Environmental Epidemiology Branch, National Cancer Institute, Bethesda, MD 20892.
authors.forename: J W
authors.initials: JW
authors.lastname: Kardaun
authors.forename: R B
authors.initials: RB
authors.lastname: Hayes
authors.forename: L M
authors.initials: LM
authors.lastname: Pottern
authors.forename: L M
authors.initials: LM
authors.lastname: Brown
authors.forename: R N
authors.initials: RN
authors.lastname: Hoover
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D004407:Dysgerminoma / Q000453:epidemiology / Q000209:etiology*; D005220:Fathers; D005260:Female; D006281:Health Occupations; D006801:Humans; D008297:Male; D016273:Occupational Exposure / Q000009:adverse effects*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011795:Surveys and Questionnaires; D013736:Testicular Neoplasms / Q000453:epidemiology / Q000209:etiology*; D014481:United States / Q000453:epidemiology