[Cardiohemodynamics and microcirculation in patients with ischemic heart disease undergoing beta-adrenergic receptor stimulation and blockade].
A study of 76 patients with ischemic heart disease is presented who revealed during coronography stenosis of one-three coronary arteries equalling 50-75% of the vessel lumen. Analysis of the effect of anaprilin and nonachlazin on the clinical course and hemodynamics revealed that in patients with initial coronary atherosclerosis of middle age beta-adrenodependent vasodilation of the coronary arteries decreased. In these patients anaprilin may increase the frequency of attacks of spontaneous stenocardia. On the contrary, nonachlazin reduces manifestations of stenocardia but it may be used only in patients with a high tolerance to physical load.
Piatak
O A
OA
Lizogub
V G
VG
Kozlov
V V
VV
D000318:Adrenergic beta-Agonists / Q000627:therapeutic use*; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D003228:Conjunctiva / Q000098:blood supply*; D003324:Coronary Artery Disease / Q000188:drug therapy / Q000503:physiopathology; D004341:Drug Evaluation; D005080:Exercise Test; D006321:Heart / Q000187:drug effects* / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008833:Microcirculation / Q000187:drug effects / Q000503:physiopathology; D009628:Nonachlazine / Q000008:administration & dosage; D011433:Propranolol / Q000008:administration & dosage
D000318:Adrenergic beta-Agonists; D000319:Adrenergic beta-Antagonists; D009628:Nonachlazine; D011433:Propranolol
Kardiogemodinamika i mikrotsirkuliatsiia u bol'nykh ishemicheskoĭ bolezn'iu serdtsa pri stimuliatsii i blokade beta-adrenergicheskikh retseptorov.