[The effect of histamine H1 receptors on the secretory function and blood flow in the gastric mucosa].
In chronic experiments on dogs with the gastric fistulas it was shown that H1-histamine blockers (suprastin, peritol, pipolphen) fail to enhance histamine secretion and a selective H1-agonist IEM-813 fails to suppress it. It was also found that the ability of pipolphen to suppress the gastric secretion was due to its cholinolytic properties.
Beregovaia
T V
TV
Khomenko
T A
TA
Gubkin
V A
VA
D000640:Amitrole / Q000031:analogs & derivatives / Q000494:pharmacology; D000818:Animals; D002217:Carbachol / Q000494:pharmacology; D004285:Dogs; D005753:Gastric Mucosa / Q000098:blood supply* / Q000187:drug effects / Q000378:metabolism*; D006632:Histamine / Q000494:pharmacology; D006634:Histamine H1 Antagonists / Q000494:pharmacology; D051381:Rats; D011969:Receptors, Histamine H1 / Q000187:drug effects / Q000502:physiology*
D006634:Histamine H1 Antagonists; D011969:Receptors, Histamine H1; C014907:3-(beta-aminoethyl)-5-methyl-1,2,4-triazole; D006632:Histamine; D002217:Carbachol; D000640:Amitrole
Issledovanie vliianiia gistaminovykh H1-retseptorov na sekretornuiu funktsiiu i krovotok v slizistoĭ obolochke zheludka.