Structure and physical map of the genome of parma wallaby herpesvirus.
The DNA of parma wallaby herpesvirus (macropodid herpesvirus 1; MHV-1) was analysed by restriction mapping and Southern hybridizations, and clones of EcoRI and SalI fragments were prepared which represented approximately 85% of the genome. It has a length of about 135 kbp consisting of a long unique sequence joined to a short unique sequence bounded by inverted repeat sequences, and occurs as 2 isomers. These findings place MHV-1 in the herpesvirus structural classification Group D, along with equine herpesvirus 1 and pseudorabies virus, and differentiates it from the other known herpesvirus of Australian marsupials.
Johnson
M A
MA
School of Biological Sciences, Macquarie University, Sydney, Australia.
Whalley
J M
JM
D000818:Animals; D015139:Blotting, Southern; D002478:Cells, Cultured; D003001:Cloning, Molecular; D004279:DNA, Viral / Q000032:analysis*; D006564:Herpesviridae / Q000145:classification / Q000235:genetics*; D011558:Herpesvirus 1, Suid / Q000145:classification / Q000235:genetics; D008394:Marsupialia / Q000235:genetics / Q000382:microbiology*; D015183:Restriction Mapping
D004279:DNA, Viral