[Successful cyclosporin therapy of acquired hemophilia caused by factor VIII (VIII:C) inhibiting antibody].
A 47-year-old woman is reported who had a life-threatening, subarachnoideal bleeding due to the spontaneous development of factor VIII:C inhibitor. Cyclosporin combined with prednisone allowed a full recovery and the elimination of antibody even when other therapeutic facilities failed to be effective. Actual problems of treatment of factor VIII inhibitors are briefly surveyed.
Pfliegler
G
G
Debreceni Orvostudományi Egyetem II. sz. Belgyógyászati Klinika.
Boda
Z
Z
Hársfalvi
J
J
Flóra-Nagy
M
M
Sári
B
B
Pecze
K
K
Rák
K
K
D000906:Antibodies; D003524:Cyclosporins / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005169:Factor VIII / Q000037:antagonists & inhibitors* / Q000276:immunology; D005260:Female; D006467:Hemophilia A / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D006801:Humans; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use*
D000906:Antibodies; D003524:Cyclosporins; D005169:Factor VIII; D011241:Prednisone
VIII-as faktor (VIII:C) ellenes gátlótest okozta szerzett haemophilia sikeres kezelése cyclosporinnal.