[Dynamics of structural parameters of mast cells and accumulation of collagen fibers during radiation-induced pneumosclerosis in rats (a quantitative study)].
The methods of stereometry were used to study dynamics of accumulation of collagen fibres and alteration of the number, sizes and state of mast cells of rat lung during the period of 12 months after single local X-irradiation with doses of 10, 14.3 and 20 Gy. A statistically significant correlation between the number of mast cells and spatial density of collagen fibres in the exposed pulmonary tissue was shown. Severity of changes in the structural characteristics of mast cells and the degree of collagen fibres accumulation were a function of radiation dose.
Dubrovskaia
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D000818:Animals; D003094:Collagen / Q000528:radiation effects; D008168:Lung / Q000473:pathology / Q000528:radiation effects*; D008171:Lung Diseases / Q000209:etiology* / Q000473:pathology; D008297:Male; D008407:Mast Cells / Q000528:radiation effects; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000473:pathology*; D051381:Rats; D012598:Sclerosis / Q000473:pathology
D003094:Collagen
Dinamika strukturnykh parametrov tuchnykh kletok i nakopleniia kollagenovykh volokon v protsesse formirovaniia radioindutsirovannogo pnevmoskleroza u krys (kolichestvennoe issledovanie).