title: Genetic comparison of ovine and bovine pestiviruses.
abstract: Viral RNA oligonucleotide fingerprinting was used to compare genetic relationship among pestiviruses originating from ovine or bovine host species. Ovine pestiviruses, including reference border disease virus and 2 border disease isolates originating from natural pestivirus infections of sheep, appeared to have a more distant genetic relationship among themselves than with certain bovine pestiviruses. A closer genetic relatedness was evident between border disease virus and 3 noncytopathic bovine pestiviruses, including Draper bovine viral diarrhea virus (BVDV), a BVDV isolate that originated from aborted bovine fetuses, and a virus that was isolated from the serum of a calf that had a chronic BVDV infection. Four noncytopathic bovine viruses, including Draper BVDV and 3 field isolates, were closely related. Reference Oregon C24V BVDV, a cytopathic virus, was closely related to only 1 of the 7 noncytopathic viruses in this study.
authors.affiliation: Department of Veterinary Science, University of Nebraska, Lincoln 68583-0905.
authors.forename: C L
authors.initials: CL
authors.lastname: Kelling
authors.forename: J E
authors.initials: JE
authors.lastname: Kennedy
authors.forename: L C
authors.initials: LC
authors.lastname: Stine
authors.forename: K K
authors.initials: KK
authors.lastname: Rump
authors.forename: P S
authors.initials: PS
authors.lastname: Paul
authors.forename: J E
authors.initials: JE
authors.lastname: Partridge
mesh_terms: D000818:Animals; D001882:Border Disease / Q000382:microbiology*; D002417:Cattle; D001908:Diarrhea Viruses, Bovine Viral / Q000235:genetics*; D009710:Nucleotide Mapping / Q000379:methods; D012367:RNA, Viral / Q000032:analysis* / Q000235:genetics; D012302:Rinderpest virus / Q000145:classification / Q000235:genetics*; D012756:Sheep
chemical_list: D012367:RNA, Viral