Linkage analysis in Marfan syndrome.
We have analysed 40 marker loci on 13 chromosomes for linkage with Marfan syndrome. None of the loci was linked to the Marfan syndrome locus at theta = 0.00. This study provides a basis for an exclusion map and for further collaboration in mapping of the locus.
Schwartz
R C
RC
Department of Pediatrics, University of Connecticut Health Center, Farmington 06032.
Blanton
S H
SH
Hyde
C A
CA
Sottile
T R
TR
Hudgins
L
L
Sarfarazi
M
M
Tsipouras
P
P
D000483:Alleles; D002874:Chromosome Mapping; D003201:Computers; D015342:DNA Probes; D005260:Female; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D008126:Lod Score; D008297:Male; D008382:Marfan Syndrome / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length
D015342:DNA Probes; D005819:Genetic Markers