title: Evaluation of the Damus-Kaye-Stansel operation in infancy.
abstract: Thirteen patients, 12 of whom younger than 2 years, underwent a Damus-Kaye-Stansel procedure for complete transposition of the great arteries, ventricular septal defect, or double-outlet right ventricle and subpulmonary ventricular septal defect. In 6 patients, associated cardiac anomalies caused systemic flow obstruction. There were six hospital deaths (mortality rate, 42%). In a mean follow-up period of 57 months, 5 of 7 survivors required relief of right ventricular hypertension through conduit replacement or enlargement (4 patients) or conduit valve balloon dilation (1 patient). The aortic valve became regurgitant in 2 patients in whom it had been left in potential connection with the right ventricle. One patient has moderate pulmonary valve regurgitation. The main advantage of the Damus-Kaye-Stansel procedure is that it avoids coronary relocation; also, the spatial relationship of the great arteries and the coronary anatomy do not affect its feasibility. One drawback is the need for a conduit in infancy. Our present indication for Damus-Kaye-Stansel procedure is confined to double-outlet right ventricle with subpulmonary ventricular septal defect; 5 of 6 patients survived repair in this series. Possible indications are for patients with associated subaortic obstruction or unusual coronary arrangements. Fresh or cryopreserved homografts as extracardiac conduits and primary closure of the subaortic area may reduce the need for reoperation after Damus-Kaye-Stansel procedure.
authors.affiliation: Dipartimento Medico-Chirurgico di Cardiologia Pediatrica, Ospedale Bambino Gesù, Roma, Italia.
authors.forename: D C
authors.initials: DC
authors.lastname: di Carlo
authors.forename: R M
authors.initials: RM
authors.lastname: Di Donato
authors.forename: A
authors.initials: A
authors.lastname: Carotti
authors.forename: L
authors.initials: L
authors.lastname: Ballerini
authors.forename: C
authors.initials: C
authors.lastname: Marcelletti
mesh_terms: D001807:Blood Vessel Prosthesis; D004310:Double Outlet Right Ventricle / Q000401:mortality / Q000601:surgery*; D005500:Follow-Up Studies; D006345:Heart Septal Defects, Ventricular / Q000401:mortality / Q000601:surgery*; D017052:Hospital Mortality; D006801:Humans; D007231:Infant, Newborn; D012086:Reoperation; D013997:Time Factors; D014188:Transposition of Great Vessels / Q000401:mortality / Q000601:surgery*