title: Cytogenetic characterization of congenital or infantile fibrosarcoma.
abstract: Chromosome analysis of a congenital or infantile fibrosarcoma from the lower left leg of a 3-week-old baby girl showed only numerical changes involving chromosomes 11, 17 and 20. As three more cases with similar combinations of trisomies of the same chromosomes have been described, this report confirms that adult and congenital fibrosarcoma are cytogenetically different and trisomy 11 may be the key-event.
authors.affiliation: Department of Paediatrics, University of Leuven, Belgium.
authors.forename: P
authors.initials: P
authors.lastname: Dal Cin
authors.forename: P
authors.initials: P
authors.lastname: Brock
authors.forename: M
authors.initials: M
authors.lastname: Casteels-Van Daele
authors.forename: I
authors.initials: I
authors.lastname: De Wever
authors.forename: B
authors.initials: B
authors.lastname: Van Damme
authors.forename: H
authors.initials: H
authors.lastname: Van den Berghe
mesh_terms: D002880:Chromosomes, Human, Pair 11; D002886:Chromosomes, Human, Pair 17; D002890:Chromosomes, Human, Pair 20; D005260:Female; D005354:Fibrosarcoma / Q000151:congenital / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D007866:Leg; D012983:Soft Tissue Neoplasms / Q000151:congenital / Q000235:genetics* / Q000473:pathology; D014314:Trisomy