[The role of the hypophysis and STH in the regulation of the androgenic receptor level of the rat liver and in the realization of the sex-differentiating action of gonadal hormones].
The role of the pituitary gland was investigated in the regulation of the level of rat liver androgenic receptors (AR) and in the realization of polydifferentiating action of gonadal hormones. The level of AR in the female and male rat liver was shown not to depend directly on the presence of the pituitary gland or STH administration. The pituitary gland is not a mediator in the realization of polydifferentiating action of androgens and estrogens. STH enhances the development of a positive effect of androgens on the level of AR.
Oleĭnik
N V
NV
Smirnova
O V
OV
Rozen
V B
VB
D000728:Androgens / Q000502:physiology*; D000818:Animals; D005260:Female; D012739:Gonadal Steroid Hormones / Q000494:pharmacology*; D013006:Growth Hormone / Q000502:physiology*; D007016:Hypophysectomy; D008099:Liver / Q000187:drug effects / Q000502:physiology*; D008297:Male; D009919:Orchiectomy; D010052:Ovariectomy; D010902:Pituitary Gland / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D011956:Receptors, Cell Surface / Q000187:drug effects / Q000502:physiology*; D012727:Sex Characteristics
D000728:Androgens; D012739:Gonadal Steroid Hormones; D011956:Receptors, Cell Surface; D013006:Growth Hormone
Rol' gipofiza i STG v reguliatsii urovnia androgennykh retseptorov pecheni krys i v realizatsii poldifferentsiruiushchego deĭstviia gormonov gonad.