Chemical structure of glycosphingolipids isolated from Sphingomonas paucimobilis.
Two novel glycosphingolipids were isolated from Sphingomonas paucimobilis and their structures were completely elucidated. The glycosyl portion of the glycosphingolipid consists of an alpha-D-Manp-[1----2)-alpha-D-Galp-(1----6)-alpha-D-GlcpN-(1 ----4)-alpha-D- GlcpA-R tetrasaccharide. The hydrophobic residue R was found to be heterogeneous with respect to the dihydrosphingosine residue. Erythro-1,3-dihydroxy-2-amino-octadecane and erythro-1,3-dihydroxy-2-amino-cis-13,14-methyleneoctadecane were identified in comparable amounts. Both dihydrosphingosine derivatives were quantitatively substituted by an (S)-2-hydroxymyristic acid in amide linkage.
Kawahara
K
K
Department of Bacteriology, Kitasato Institute, Tokyo, Japan.
Seydel
U
U
Matsuura
M
M
Danbara
H
H
Rietschel
E T
ET
Zähringer
U
U
D006028:Glycosphingolipids / Q000737:chemistry* / Q000302:isolation & purification; D006868:Hydrolysis; D007834:Lasers; D008055:Lipids / Q000032:analysis; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008745:Methylation; D009844:Oligosaccharides / Q000737:chemistry; D011549:Pseudomonas / Q000378:metabolism*
D006028:Glycosphingolipids; D008055:Lipids; D009844:Oligosaccharides