title: Oestrogen receptors in conjunctival malignant melanoma: immunocytochemical study using formalin fixed paraffin wax sections.
abstract: In a group of 15 women with conjunctival malignant melanoma six cases (40%) were shown to have oestrogen receptor positivity using a monoclonal antibody to oestrogen receptor related antigen (ER-D5, Amersham RPN.710) on formalin fixed, paraffin wax sections. Receptors were also present in the epithelium of these six cases but not in controls and cases without ER-D5 positivity in their tumours. A subset of these aggressive, intractable unilateral tumours may therefore be amenable to hormone treatment.
authors.affiliation: Department of Pathology, London.
authors.forename: D A
authors.initials: DA
authors.lastname: Paridaens
authors.forename: R A
authors.initials: RA
authors.lastname: Alexander
authors.forename: J L
authors.initials: JL
authors.lastname: Hungerford
authors.forename: A C
authors.initials: AC
authors.lastname: McCartney
mesh_terms: D000293:Adolescent; D000328:Adult; D000911:Antibodies, Monoclonal; D003230:Conjunctival Neoplasms / Q000737:chemistry*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008545:Melanoma / Q000737:chemistry*; D008875:Middle Aged; D009376:Neoplasms, Hormone-Dependent / Q000737:chemistry*; D016612:Paraffin Embedding; D011960:Receptors, Estrogen / Q000032:analysis*; D012189:Retrospective Studies
chemical_list: D000911:Antibodies, Monoclonal; D011960:Receptors, Estrogen