Efficacy of chemical and/or surgical therapy against condylomata acuminata: a retrospective evaluation.
In order to estimate treatment resistance of condylomas, standardized records of 230 males aged 17-80 years (mean 27) attending at an STD clinic were analysed retrospectively. Anal warts occurred in 38 (17%) men; in 19 (50%) intranal warts were extensive enough to require further referral to the Department of Surgery. Urinary meatal warts occurred in 30 men; 9 of them (30%) were referred to the Department of Urology. The remaining 202 (88%) men were treated in the STD clinic with simple surgery and/or home-treatment with 0.5% podophyllotoxin-ethanol twice a day for one or more 3 day sessions. After a follow-up of at least one year, 46 (23%) patients still had condylomas. However, 77 (49%) of the remaining 156 men were cured after a single therapeutic session, and after 1-4 sessions the cumulative cure rate was 77%.
von Krogh
G
G
Department of Dermatovenereology, Karolinska Hospital, Stockholm, Sweden.
Wikström
A
A
D000293:Adolescent; D000328:Adult; D000368:Aged; D001005:Anus Neoplasms / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery*; D003131:Combined Modality Therapy; D003218:Condylomata Acuminata / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery*; D005500:Follow-Up Studies; D005834:Genital Neoplasms, Male / Q000188:drug therapy / Q000453:epidemiology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011034:Podophyllotoxin / Q000008:administration & dosage / Q000627:therapeutic use*; D012017:Referral and Consultation / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012307:Risk Factors; D012725:Sexual Behavior; D013548:Sweden / Q000453:epidemiology; D016896:Treatment Outcome
D011034:Podophyllotoxin