title: [The immunological aspects of the periodization of the course of craniocerebral trauma].
abstract: The dynamics of changes of immunological parameters were studied in 383 patients with various types of craniocerebral trauma (CCT) in the acute and late-term periods. It was established that the immunological processes in CCT occur in stages. The phases can be distinguished in the acute period: stress reaction (1st-3rd day), phase of maximal changes (7th-21st day), and normalization of the immunological parameters (30th-45th day). A wave of recurrent aggravation of the immunological parameters occurs on the 8th-14th day after CCT in an organism sensitized to the brain antigen, which is linked with autoaggressive damage to the brain.
authors.forename: V I
authors.initials: VI
authors.lastname: Gorbunov
authors.forename: I V
authors.initials: IV
authors.lastname: Gannushkina
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology; D001930:Brain Injuries / Q000145:classification / Q000276:immunology*; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008875:Middle Aged; D010507:Periodicity; D013601:T-Lymphocytes / Q000276:immunology; D013997:Time Factors
chemical_list: D007136:Immunoglobulins
vernacular_title: Immunologicheskie aspekty periodizatsii techeniia cherepno-mozgovoĭ travmy.