Squamous cell carcinoma developing in epidermolysis bullosa dystrophica.
Two patients with epidermolysis bullosa dystrophica recessiva who had squamous cell carcinoma are presented. Case 1 is a 40-year-old woman who had ulcers on her left lower leg. Case 2 is a 42-year-old man who had a tumor on his left first toe. Wide surgical excision with skin coverage by autograft was performed in case 1. Amputation of the toe in case 2 was performed. A review of the cases of epidermolysis bullosa dystrophica associated with cancer reported in Japan is also presented.
Yoshioka
K
K
Department of Dermatology, Osaka City University Medical School, Japan.
Kono
T
T
Kitajima
J
J
Nakagawa
K
K
Yashiro
N
N
Taniguchi
S
S
Furukawa
M
M
Hamada
T
T
D000328:Adult; D000368:Aged; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D002648:Child; D016108:Epidermolysis Bullosa Dystrophica / Q000150:complications* / Q000453:epidemiology / Q000473:pathology; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology