An interspecific backcross linkage map of the proximal half of mouse chromosome 14.
We have generated a 30-cM molecular genetic linkage map of the proximal half of mouse chromosome 14 by interspecific backcross analysis. Loci that were mapped in this study include Bmp-1, Ctla-1, Hap, hr, Plau, Psp-2, Rib-1, and Tcra. A region of homology between mouse chromosome 14 and human chromosome 10 was identified by the localization of Plau to chromosome 14. This interspecific backcross map will be valuable for establishing linkage relationships of additional loci to mouse chromosome 14.
Ceci
J D
JD
Mammalian Genetics Laboratory, NCI-Frederick Cancer Research Facility, Maryland 21701.
Kingsley
D M
DM
Silan
C M
CM
Copeland
N G
NG
Jenkins
N A
NA
D000818:Animals; D002874:Chromosome Mapping; D002879:Chromosomes, Human, Pair 10; D003433:Crosses, Genetic; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D051379:Mice; D008810:Mice, Inbred C57BL / Q000235:genetics; D009115:Muridae / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length; D012689:Sequence Homology, Nucleic Acid; D013045:Species Specificity
D005819:Genetic Markers