The effect of O2-lack on the cerebrum in neonatal rabbits: first results of an in vivo NMR 31P-spectroscopic study.
Two- and 10-day-old urethan anesthetized rabbits were investigated. The ATP content as well as the intracellular pH-value were analysed during hypoxia and following reoxygenation. In contrast to the 2-day-old animals, we found delayed decreasing ATP content in 10-day-old rabbits as well as a delayed increase during the reoxygenation. The return to normal pH-values during the reoxygenation takes more time in older animals.
Schönfelder
J
J
Institut of Pathological Physiology, University of Leipzig, F.R.G.
Gründer
W
W
D000255:Adenosine Triphosphate / Q000378:metabolism; D000375:Aging / Q000502:physiology; D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development / Q000502:physiology*; D001921:Brain / Q000378:metabolism* / Q000473:pathology; D001927:Brain Diseases / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology; D006863:Hydrogen-Ion Concentration; D009682:Magnetic Resonance Spectroscopy; D009994:Osmolar Concentration; D010100:Oxygen / Q000378:metabolism* / Q000494:pharmacology; D010758:Phosphorus; D011817:Rabbits
D010758:Phosphorus; D000255:Adenosine Triphosphate; D010100:Oxygen