title: Neuroblastoma in a dwarfed newborn. Possible clue to the chromosomal localization of the gene for achondroplasia?
abstract: The authors report a premature achondroplastic child with connatal neuroblastoma. Though this association could be coincidental, we suggest that a microdeletion inducing a contiguous gene syndrome involving the locus of neuroblastoma suppressor gene could be an alternative hypothesis. The gives a working hypothesis for the localization of the gene for achondroplasia.
authors.affiliation: Centre for Human Genetics, CHU Sart Tilman, Liége, Belgium.
authors.forename: A
authors.initials: A
authors.lastname: Verloes
authors.forename: B
authors.initials: B
authors.lastname: Massart
authors.forename: V
authors.initials: V
authors.lastname: Jossa
authors.forename: J P
authors.initials: JP
authors.lastname: Langhendries
authors.forename: H
authors.initials: H
authors.lastname: Hainaut
authors.forename: J P
authors.initials: JP
authors.lastname: Paquot
authors.forename: L
authors.initials: L
authors.lastname: Koulischer
mesh_terms: D000130:Achondroplasia / Q000150:complications / Q000151:congenital / Q000235:genetics*; D002872:Chromosome Deletion; D002878:Chromosomes, Human, Pair 1; D004200:Diseases in Twins; D016147:Genes, Tumor Suppressor; D008040:Genetic Linkage; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000235:genetics*; D008297:Male; D009447:Neuroblastoma / Q000150:complications / Q000151:congenital* / Q000235:genetics; D013899:Thoracic Neoplasms / Q000150:complications / Q000151:congenital* / Q000235:genetics; D014429:Twins, Dizygotic