[The local immunity status of breast cancer patients depending on the level of estrogen receptors in the tumor].
Studies of local immunity in breast cancer patients were performed in relation to its dependence on tumor levels of estrogen receptors. They demonstrated that progression of breast cancer depends much on the presence of estrogen receptors which occur in 33% of premenopausal and in 68.3% of postmenopausal women; local humoral immunity depends on hormonal presentation of the tumor. When the latter contains estrogen receptors, synthesis of IgSA (stage I-IIa) and of IgSA, A, IgG, IgM (stage IIb-IIIb) appears inhibited; less affected is local immunity with negative estrogen receptors in the tumor as evidenced by the reduction or absence of IgSA in a half (stage I-IIa) or all cases (stage IIb-IIIb) in unchanged levels of the other immunoglobulins.
Kochetkova
V A
VA
Dzhubalieva
S K
SK
D000328:Adult; D000368:Aged; D000917:Antibody Formation / Q000276:immunology; D001940:Breast / Q000737:chemistry / Q000276:immunology*; D001943:Breast Neoplasms / Q000737:chemistry / Q000276:immunology*; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008593:Menopause / Q000276:immunology; D008598:Menstruation / Q000276:immunology; D008875:Middle Aged; D011960:Receptors, Estrogen / Q000032:analysis / Q000276:immunology*
D007136:Immunoglobulins; D011960:Receptors, Estrogen
Sostoianie mestnogo immuniteta u bol'nykh rakom molochnoĭ zhelezy v zavisimosti ot urovnia éstrogennykh retseptorov v opukholi.