[Albofungin formation by a strain isolated as a result of fusion of protoplasts of organisms producing aminoglycoside antibiotics].
Strain 344 synthesizing an antibiotic complex was isolated after fusion of the protoplasts of Streptomyces monomycini producing monomycin and Streptomyces kanamyceticus producing kanamycin. The major component of the complex was identified with albofungin and the minor one was suggested to be chloralbofungin. In the cultures of strain 344 variants forming monomycin were detected. After regeneration of the protoplasts of the parent strains there were isolated no stable clones synthesizing antibiotics differing from monomycin and kanamycin.
Malanicheva
I A
IA
Koz'mian
L I
LI
Dudnik
Iu V
IuV
Novozhenov
M Iu
MIu
Laĭko
A V
AV
Potapova
N P
NP
D000900:Anti-Bacterial Agents / Q000096:biosynthesis* / Q000378:metabolism*; D002459:Cell Fusion; D015643:Erythromycin Ethylsuccinate / Q000378:metabolism; D007546:Isoquinolines / Q000378:metabolism; D007612:Kanamycin / Q000378:metabolism; D015394:Molecular Structure; D011523:Protoplasts / Q000166:cytology / Q000378:metabolism*; D013302:Streptomyces / Q000378:metabolism*; D014966:Xanthenes / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D007546:Isoquinolines; D014966:Xanthenes; D015643:Erythromycin Ethylsuccinate; C071615:chloroalbofungin; D007612:Kanamycin; C016969:albofungin
Obrazovanie al'bofungina shtammon, poluchennym v rezul'tate sliianiia protoplastov produtsentov aminoglikozidnykh antibiotikov.