title: [Baroreflex and blood pressure variations in borderline hypertension of the young adult].
abstract: Blood pressure (BP) variability depends on external and internal factors. Among these, arterial baroreflex play an important role. The matter of this study is to assess the relationship between these two parameters in borderline hypertension (BL). Twenty six BL male hypertensive were recruited for the study, all gave informed consent. Age: 21 +/- 2 years, height: 177 +/- 8 cm, weight: 77 +/- 14 kg. An ambulatory BP monitoring was performed in each one using a Diasys (Novacor) recorder. Measurements were obtained each 15 minutes for 24 hours. Mean, standard deviation and variation coefficient (VC) of BP and heart rate (HR) were computed for 24 hours, daytime (9a.m.-7 p.m.), nighttime (11 p.m.-7 a.m.). Baroreflex sensitivity (BRS) was determined as the ratio of HR variation on systolic BP variation recorded with a Finapres device from the fourth phase of a Valsalva manoeuvre. Mean systolic and diastolic BP values for 24 hours, daytime and nighttime are: 129 +/- 11/73 +/- 13, 137 +/- 14/76 +/- 15, 114 +/- 11/69 +/- 12 mmHg. VC are: 12 +/- 3/15 +/- 3, 9 +/- 3/13 +/- 3, 10 +/- 3/13 +/- 4%. HR values are: 73 +/- 10, 84 +/- 14, 58 +/- 7 b/min, VC are: 24 +/- 5, 17 +/- 4, 17 +/- 7%. Index for BRS = 1.76 +/- 0.65%. There is no correlation between BRS and systolic BP or HR. BRS is correlated to the inverse of systolic daytime BP VC: r = -0.556, p = 0.003. There is no correlation with other parameters. This study provides evidence for a link between BRS and daytime BP variability in borderline hypertension.
authors.affiliation: Service de pathologie cardiovasculaire, hôpital d'instruction des armées Begin, Saint-Mandé.
authors.forename: X
authors.initials: X
authors.lastname: Chanudet
authors.forename: N P
authors.initials: NP
authors.lastname: Chau
authors.forename: O
authors.initials: O
authors.lastname: Hoffman
authors.forename: Y
authors.initials: Y
authors.lastname: Fassa
authors.forename: R
authors.initials: R
authors.lastname: Clément
authors.forename: J M
authors.initials: JM
authors.lastname: Garcin
authors.forename: P
authors.initials: P
authors.lastname: Larroque
mesh_terms: D000328:Adult; D001794:Blood Pressure; D015924:Blood Pressure Monitors; D006339:Heart Rate; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D011311:Pressoreceptors / Q000503:physiopathology*; D014636:Valsalva Maneuver
vernacular_title: Baroréflexe et variabilité tensionnelle dans l'hypertension artérielle limite de l'adulte jeune.