title: Fructose transport by Escherichia coli.
abstract: The utilization of fructose by Escherichia coli involves, as first step, the uptake of the sugar, normally via the phosphoenolpyruvate-dependent phosphotransferase system (PTS). This fructose-specific PTS differs in several ways from that effecting the uptake of other sugars that also possess the 3,4,5-D-arabino-hexose configuration: these differences are discussed. Mutants that lack the genes ptsI and ptsH, which specify components of the PTS common to most PT-sugars, can mutate further to regain the ability to utilize fructose when this is present in relatively high concentration (i.e. greater than 2 mM) in the medium. Some of the properties of this unusual uptake system is discussed.
authors.affiliation: Department of Biochemistry, University of Cambridge, U.K.
authors.forename: H L
authors.initials: HL
authors.lastname: Kornberg
mesh_terms: D001426:Bacterial Proteins / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism; D004926:Escherichia coli / Q000378:metabolism*; D005632:Fructose / Q000378:metabolism*; D010731:Phosphoenolpyruvate Sugar Phosphotransferase System / Q000378:metabolism*; D011487:Protein Conformation
chemical_list: D001426:Bacterial Proteins; D005632:Fructose; D010731:Phosphoenolpyruvate Sugar Phosphotransferase System; C030182:phosphocarrier protein HPr