Rejection of transgenic skin expressing a xeno-class I antigen is CD4-dependent and CD8-independent.
Auchincloss
H
H
Department of Surgery, Massachusetts General Hospital, Boston 02114.
Moses
R
R
Conti
D
D
Sundt
T
T
Smith
C
C
Sachs
D H
DH
Winn
H J
HJ
D000818:Animals; D000945:Antigens, Differentiation, T-Lymphocyte / Q000276:immunology*; D015704:CD4 Antigens / Q000276:immunology*; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D016827:CD8 Antigens; D003602:Cytotoxicity, Immunologic / Q000276:immunology; D006084:Graft Rejection / Q000276:immunology*; D015395:Histocompatibility Antigens Class I / Q000032:analysis*; D051379:Mice; D008810:Mice, Inbred C57BL; D008822:Mice, Transgenic; D016038:Skin Transplantation / Q000276:immunology*; D013552:Swine; D013556:Swine, Miniature; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*; D014183:Transplantation, Heterologous / Q000276:immunology
D000945:Antigens, Differentiation, T-Lymphocyte; D015704:CD4 Antigens; D016827:CD8 Antigens; D015395:Histocompatibility Antigens Class I