[Adrenaline-induced platelet aggregation and blood pressure in normal subjects].
Epinephrine- and collagen-induced aggregation of platelets was determined under standardized conditions in vitro in 100 healthy normotonic subjects, and the relation between the platelet-parameters and diastolic and systolic blood pressure analysed. A correlation between aggregation and blood pressure could be demonstrated only in the case of epinephrine-induced aggregation. Intensity of epinephrine-induced aggregation correlated well with the simultaneously measured diastolic and systolic blood pressure and with the calculated mean arterial pressure (R = 0.775; p less than 0.001). From the results it can be concluded, that the correlation between epinephrine-induced aggregation and blood pressure depends on endogenous levels of catecholamines.
Noelle
G
G
Teutoburger-Wald-Klinik, Bad Rothenfelde.
Reuter
H D
HD
D000293:Adolescent; D000328:Adult; D001794:Blood Pressure / Q000187:drug effects*; D003094:Collagen / Q000494:pharmacology; D004837:Epinephrine / Q000494:pharmacology*; D006801:Humans; D008297:Male; D010974:Platelet Aggregation / Q000187:drug effects*
D003094:Collagen; D004837:Epinephrine
Adrenalininduzierte Thrombozytenaggregation und Blutdruckverhalten bei Normalprobanden.