Adriamycin-induced cardiomyopathy aggravated by cis-platinum nephrotoxicity requiring dialysis.
Complications of chemotherapy for a synovial sarcoma in an eight-year old boy included cisplatinum nephrotoxicity and adriamycin cardiotoxicity. The resultant renal failure and fluid overload necessitated peritoneal dialysis. Intractable hypomagnesemia was also a prominent feature.
Tay
H N
HN
Department of Physiology, National University of Singapore.
Yap
H K
HK
Murugasu
B
B
Quah
T C
TC
Tay
S H
SH
Lim
J W
JW
D058186:Acute Kidney Injury / Q000139:chemically induced / Q000628:therapy; D002303:Cardiac Output, Low / Q000139:chemically induced* / Q000628:therapy; D002648:Child; D002945:Cisplatin / Q000009:adverse effects* / Q000627:therapeutic use; D004317:Doxorubicin / Q000009:adverse effects* / Q000627:therapeutic use; D005266:Femoral Neoplasms / Q000188:drug therapy; D018219:Histiocytoma, Benign Fibrous / Q000188:drug therapy; D006801:Humans; D008275:Magnesium Deficiency / Q000139:chemically induced / Q000628:therapy; D008297:Male; D010530:Peritoneal Dialysis
D004317:Doxorubicin; D002945:Cisplatin