Intraperitoneal injection of human recombinant neutrophil-activating factor/interleukin 8 (hrNAF/IL-8) produces a T cell and eosinophil infiltrate in the guinea pig lung. Effect of PAF antagonist WEB2086.
Burrows
L J
LJ
Department of Pharmacology, Hunterian Institute Royal College of Surgeons, London, England.
Piper
P J
PJ
Lindley
I D
ID
Westwick
J
J
D000818:Animals; D001381:Azepines / Q000494:pharmacology*; D004804:Eosinophils / Q000187:drug effects / Q000502:physiology*; D006168:Guinea Pigs; D006801:Humans; D007274:Injections, Intraperitoneal; D016209:Interleukin-8 / Q000008:administration & dosage / Q000494:pharmacology*; D007700:Kinetics; D008168:Lung / Q000187:drug effects / Q000502:physiology*; D010972:Platelet Activating Factor / Q000037:antagonists & inhibitors*; D011650:Pulmonary Alveoli / Q000187:drug effects / Q000502:physiology*; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000494:pharmacology; D012710:Serum Albumin, Bovine / Q000494:pharmacology; D013601:T-Lymphocytes / Q000187:drug effects / Q000502:physiology*; D014230:Triazoles / Q000494:pharmacology*
D001381:Azepines; D016209:Interleukin-8; D010972:Platelet Activating Factor; D011994:Recombinant Proteins; D014230:Triazoles; C052518:WEB 2086; D012710:Serum Albumin, Bovine