Disseminated pneumocystis carinii infection in AIDS.
Eight patients with AIDS and Pneumocystis carinii infection were studied. Protean manifestations were a feature not untypical of disseminated pneumocystosis. Aerosolised pentamidine as prophylaxis against P carinii pneumonia was ineffective at suppressing dissemination. The knowledge that extrapulmonary infection can occur has implications for the detection and treatment of, and prophylaxis against, P carinii infection. The survival of patients with disseminated pneumocystosis is particularly poor, and may be due to a lack of clinical awareness and consequent delay in diagnosis.
Coker
R J
RJ
Department of Genitourinary Medicine, St. Mary's Hospital and Medical School, London.
Clark
D
D
Claydon
E L
EL
Gompels
M
M
Ainsworth
J G
JG
Lucas
S B
SB
Miller
R
R
Goldin
R D
RD
Pinching
A J
AJ
Harris
J R
JR
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D001706:Biopsy; D006801:Humans; D008297:Male; D009894:Opportunistic Infections / Q000150:complications* / Q000473:pathology; D016720:Pneumocystis Infections / Q000150:complications* / Q000473:pathology; D011020:Pneumonia, Pneumocystis / Q000150:complications