title: Corrected sequence of the mannitol (mtl) operon in Escherichia coli.
abstract: The previously published sequences of the operator-promoter region of the mannitol operon of Escherichia coli and of the mtlD gene have been found to contain a number of errors. The major conclusions reported previously were correct, but additionally it is now clear that a C-terminal portion of mannitol-1-phosphate dehydrogenase (the mtlD gene product) exhibits significant sequence identity with an amino-terminal region of human liver fructose-6-phosphate-2-kinase:fructose-2,6-bisphosphatase.
authors.affiliation: Department of Biochemistry and Nutrition, Virginia Polytechnic Institute and State University, Blacksburg 24061-0308.
authors.forename: W
authors.initials: W
authors.lastname: Jiang
authors.forename: L F
authors.initials: LF
authors.lastname: Wu
authors.forename: J
authors.initials: J
authors.lastname: Tomich
authors.forename: M H
authors.initials: MH
authors.lastname: Saier
authors.forename: W G
authors.initials: WG
authors.lastname: Niehaus
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics*; D005798:Genes, Bacterial; D006801:Humans; D008353:Mannitol / Q000378:metabolism*; D008969:Molecular Sequence Data; D009097:Multienzyme Complexes / Q000235:genetics; D009876:Operon; D025481:Phosphofructokinase-2; D010744:Phosphoric Monoester Hydrolases / Q000235:genetics; D010770:Phosphotransferases / Q000235:genetics; D011401:Promoter Regions, Genetic; D051381:Rats; D012689:Sequence Homology, Nucleic Acid; D013401:Sugar Alcohol Dehydrogenases / Q000235:genetics
chemical_list: D009097:Multienzyme Complexes; D008353:Mannitol; D013401:Sugar Alcohol Dehydrogenases; C021544:mannitol-1-phosphate dehydrogenase; D010770:Phosphotransferases; D025481:Phosphofructokinase-2; D010744:Phosphoric Monoester Hydrolases