title: Neuropsychological assessment in multiple sclerosis: a follow-up study with magnetic resonance imaging.
abstract: Nineteen moderately impaired patients with clinically definite multiple sclerosis and an initially relapsing-remitting course were included in a neuropsychological and magnetic resonance imaging (MRI) follow-up study. The average test/re-test interval was about 2 years. The neuropsychological findings were indicative of a very mild overall impairment; the patients, as a group, showed no evidence of cognitive deterioration in the follow-up period. A numerical estimation of the severity of cerebral demyelination shown by MRI did not indicate a significant change. No correlation between cognitive performance variations and MRI changes was found.
authors.affiliation: Istituto di Clinica Neurologica, University of Milan, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Mariani
authors.forename: E
authors.initials: E
authors.lastname: Farina
authors.forename: S F
authors.initials: SF
authors.lastname: Cappa
authors.forename: G P
authors.initials: GP
authors.lastname: Anzola
authors.forename: L
authors.initials: L
authors.lastname: Faglia
authors.forename: L
authors.initials: L
authors.lastname: Bevilacqua
authors.forename: R
authors.initials: R
authors.lastname: Capra
authors.forename: F
authors.initials: F
authors.lastname: Mattioli
authors.forename: L A
authors.initials: LA
authors.lastname: Vignolo
mesh_terms: D000328:Adult; D001921:Brain / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis / Q000473:pathology / Q000523:psychology*; D009483:Neuropsychological Tests