title: Hematological indices in a cohort of HTLV-I/II and HIV-1 infected intravenous drug users in New York City.
abstract: The prevalence and clinical consequences of human T-cell lymphotropic viruses types I and II (HTLV-I/II) infection in human immunodeficiency virus-1 (HIV-1) infected persons are areas of continuing interest. This article reports the preliminary findings of the hematological indices in 454 patients infected with HIV-1 and HTLV-I/HTLV-II. Based on serology, 46.2% of the patients had evidence of HIV-1 infection only, 4.6% had evidence of HTLV-I/II only, 14.3% had evidence of both HIV-1 and HTLV-I/II, and 34.8% had evidence of neither HIV-1 or HTLV-I/II. The patient group with both HTLV-I/II and HIV-1 infection had lower total white blood cell, platelet, and serum hematocrits than patients with either HIV-1 or HTLV-I/II infection. While these differences were insignificant, they do not suggest any HTLV-I/II-induced protective effect against HIV-1 related hematological consequences.
authors.affiliation: Division of Medical Services, Addiction Research and Treatment Corporation, Brooklyn, New York 11201.
authors.forename: L S
authors.initials: LS
authors.lastname: Brown
authors.forename: A
authors.initials: A
authors.lastname: Chu
authors.forename: H
authors.initials: H
authors.lastname: Lee
authors.forename: J P
authors.initials: JP
authors.lastname: Allain
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000097:blood* / Q000150:complications; D000328:Adult; D015331:Cohort Studies; D005260:Female; D015497:HIV-1; D015490:HTLV-I Infections / Q000097:blood* / Q000150:complications; D015491:HTLV-II Infections / Q000097:blood* / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D015819:Substance Abuse, Intravenous / Q000097:blood