Malignant thymoma associated with peripheral T-cell lymphocytosis.
Three cases of peripheral T-cell lymphocytosis associated with thymoma are described. Each patient had a malignant, predominantly lymphocytic thymoma with resolution of lymphocytosis upon treatment of the epithelial neoplasm. These findings suggest that lymphocytosis complicating thymoma is a paraneoplastic phenomenon and is not part of the neoplastic process.
Doll
D C
DC
Department of Medicine, Veterans Administration Hospital, Columbia, MO 65212.
Landreneau
R J
RJ
List
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AF
D000328:Adult; D000368:Aged; D015703:Antigens, CD / Q000032:analysis; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D007958:Leukocyte Count; D008218:Lymphocytosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage; D013601:T-Lymphocytes; D013945:Thymoma / Q000150:complications / Q000276:immunology / Q000473:pathology* / Q000628:therapy; D013953:Thymus Neoplasms / Q000150:complications / Q000276:immunology / Q000473:pathology* / Q000628:therapy; D014750:Vincristine / Q000008:administration & dosage
D015703:Antigens, CD; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D002945:Cisplatin; D011241:Prednisone