title: [Various factors of nonspecific resistance in pregnant women with anemia].
abstract: Eighty-two women whose pregnancy was complicated by anemias of varying severity and twelve healthy pregnant women were examined. Blood plasma immunoglobulins A, G, and M were measured by immunochemical methods, as were the immune complexes of various levels and some parameters of the homeostasis system. The findings evidence a noticeable elevation of the concentrations of all immunoglobulins, of low-disperse immune aggregates in severe anemia of pregnancy, as well as intensive synthesis of immunoglobulin M in the fetus, low level of large immune complexes, and stimulation of some homeostasis components that results in consumption coagulopathy and chronic DIC syndrome. Correlations between some parameters of the blood coagulation and fibrinolysis systems, on the one hand, and humoral immunity characteristics, on the other, may be traced, among these correlations being reverse correlations between IgG level, activated recalcification time, fibrinogen concentration, and activated partial thromboplastin time.
authors.forename: A A
authors.initials: AA
authors.lastname: Khadzhimetov
authors.forename: S N
authors.initials: SN
authors.lastname: Sultanov
authors.forename: N N
authors.initials: NN
authors.lastname: Tsybikov
mesh_terms: D000328:Adult; D000740:Anemia / Q000276:immunology*; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000209:etiology*; D007070:Immunoglobulin A / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis*; D007136:Immunoglobulins / Q000032:analysis*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000276:immunology*; D012720:Severity of Illness Index
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins
vernacular_title: Nekotorye faktory nespetsificheskoĭ rezistentnosti pri anemii beremennykh.