Effect of imipramine on depression and immune status in a sample of men with HIV infection.
Eleven men with major depression and human immunodeficiency virus (HIV) infection underwent an open trial of imipramine. Eight of nine (89%) who completed 12 weeks responded. The mean decline in T4 cells from baseline was 100 at week 12 and 16 at week 26. No major exacerbations of HIV infection occurred.
Rabkin
J G
JG
New York State Psychiatric Institute, NY 10032.
Harrison
W M
WM
D000328:Adult; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D003866:Depressive Disorder / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D006679:HIV Seropositivity / Q000150:complications / Q000276:immunology*; D006716:Homosexuality; D006801:Humans; D007099:Imipramine / Q000494:pharmacology / Q000627:therapeutic use*; D007111:Immunity, Cellular / Q000187:drug effects; D007231:Infant, Newborn; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales
D007099:Imipramine