title: [Familial cyclic neutropenia].
abstract: This rare disorder characterized by regular periodic oscillations in the number of peripheral neutrophils from normal to neutropenic levels. A case of a fourteen years old boy is presented who developed the disease at age of four years. Neutropenic periods appeared at intervals of 21 days and were associated with recurrent infections--gingivitis, stomatitis, conjunctivitis. The possible mechanism of impaired granulopoiesis and different therapeutic approaches are discussed.
authors.affiliation: Borsod-A.-Z. Megyei Kórház Gyermekegészségügyi Központ, OTE II. sz. Gyermekgyógyászati Tanszék, Miskolc.
authors.forename: G
authors.initials: G
authors.lastname: Vértesi
authors.forename: J
authors.initials: J
authors.lastname: Zsiros
authors.forename: K
authors.initials: K
authors.lastname: Nagy
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003231:Conjunctivitis / Q000209:etiology; D005891:Gingivitis / Q000209:etiology; D006801:Humans; D008297:Male; D009503:Neutropenia / Q000150:complications / Q000235:genetics* / Q000503:physiopathology; D009504:Neutrophils; D010375:Pedigree; D012008:Recurrence; D013280:Stomatitis / Q000209:etiology
vernacular_title: Familiáris megjelenésü ciklikus neutropenia.