Comparison of bopindolol and atenolol in chronic stable angina pectoris.
The efficacy of bopindolol and atenolol in the treatment of patients with chronic stable angina pectoris have been compared in a double blind, randomized study. Both bopindolol 1 mg and atenolol 100 mg for 6 weeks increased mean exercise time (25% and 22%, respectively, compared to placebo), time to angina (27% and 25%), and time to 1 mm of ST-segment depression (32% and 20%). Both drugs reduced ST-segment depression similarly at maximal and submaximal work levels. There was no significant difference in their antianginal efficacy.
Fitscha
P
P
2nd Department of Internal Medicine, Policlinic, Vienna, Austria.
Meisner
W
W
Tiso
B
B
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000368:Aged; D000787:Angina Pectoris / Q000188:drug therapy*; D001262:Atenolol / Q000627:therapeutic use*; D004311:Double-Blind Method; D005080:Exercise Test / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000008:administration & dosage; D010869:Pindolol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D011897:Random Allocation; D013997:Time Factors
D000319:Adrenergic beta-Antagonists; D001262:Atenolol; D010869:Pindolol; D005996:Nitroglycerin; C036007:bopindolol