[The role of hemocoagulation disorders in the pathogenesis and outcome of severe forms of acute pneumonia in infants and children].
As many as 249 children (age range 1 month--3 years) with acute pneumonia admitted to the department for intensive care were examined for the hemocoagulation system. Three types of changes were revealed: hypercoagulation associated with low fibrinolytic activity, coagulopathy of consumption, and hypocoagulation coupled with active fibrinolysis. Clinicomorphological correlations were done in 50 cases which eventuated in an unfavourable outcome. Circulatory disturbance which was more pronounced in hypocoagulation coupled with active fibrinolysis was the most frequently occurring morphological equivalent of hemostatic disorders. The concepts are advanced of the role played by hemocoagulation disorders in the pathogenesis of acute pneumonia in children.
Uzunova
A N
AN
Dardzhaniia
R A
RA
Gontsov
A A
AA
D000208:Acute Disease; D001778:Blood Coagulation Disorders / Q000150:complications*; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D011014:Pneumonia / Q000097:blood / Q000209:etiology*
Rol' gemokoaguliatsionnykh narushenii v patogeneze i iskhode tiazhelykh form ostroi pnevmonii u detei rannego vozrasta.