Development of protective immunity against Eimeria tenella and E. acervulina in White Leghorn chickens inoculated repeatedly with high doses of turkey coccidia.
Repeated inoculation (immunization) of 2-week-old white leghorn chickens with 10(6) oocysts of the turkey coccidia Eimeria adenoeides or E. meleagrimitis partially protected chickens against moderate challenge with E. tenella or E. acervulina oocysts, but not with E. necatrix oocysts. After challenge, mean weight gains of the immunized chickens and the unchallenged controls did not differ significantly, but weight gains of unimmunized chickens were significantly lower. The mean feed-conversion ratio of the immunized challenged chickens was 3.14, as compared with 4.42 for unimmunized challenged control chickens. In general, immunization did not markedly reduce intestinal lesions. Repeated inoculation of chickens with the turkey coccidium E. gallopavonis failed to produce statistically significant protection against challenge with E. tenella, E. acervulina, or E. necatrix, as determined by weight gain, feed-conversion efficiency, and lesion scores. Antibody profiles of individual chickens did not correlate with protection.
Augustine
P C
PC
U.S. Department of Agriculture, Livestock and Poultry Science Institute, Beltsville, Maryland 20705.
Danforth
H D
HD
Barta
J R
JR
D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D015153:Blotting, Western; D002645:Chickens / Q000469:parasitology*; D003048:Coccidiosis / Q000517:prevention & control / Q000662:veterinary*; D004435:Eating; D004539:Eimeria / Q000276:immunology*; D016786:Eimeria tenella / Q000276:immunology*; D007106:Immune Sera / Q000276:immunology; D007114:Immunization / Q000662:veterinary; D011201:Poultry Diseases / Q000517:prevention & control*; D015430:Weight Gain
D000913:Antibodies, Protozoan; D007106:Immune Sera