title: Disseminated pneumocystis carinii infection in AIDS.
abstract: Eight patients with AIDS and Pneumocystis carinii infection were studied. Protean manifestations were a feature not untypical of disseminated pneumocystosis. Aerosolised pentamidine as prophylaxis against P carinii pneumonia was ineffective at suppressing dissemination. The knowledge that extrapulmonary infection can occur has implications for the detection and treatment of, and prophylaxis against, P carinii infection. The survival of patients with disseminated pneumocystosis is particularly poor, and may be due to a lack of clinical awareness and consequent delay in diagnosis.
authors.affiliation: Department of Genitourinary Medicine, St. Mary's Hospital and Medical School, London.
authors.forename: R J
authors.initials: RJ
authors.lastname: Coker
authors.forename: D
authors.initials: D
authors.lastname: Clark
authors.forename: E L
authors.initials: EL
authors.lastname: Claydon
authors.forename: M
authors.initials: M
authors.lastname: Gompels
authors.forename: J G
authors.initials: JG
authors.lastname: Ainsworth
authors.forename: S B
authors.initials: SB
authors.lastname: Lucas
authors.forename: R
authors.initials: R
authors.lastname: Miller
authors.forename: R D
authors.initials: RD
authors.lastname: Goldin
authors.forename: A J
authors.initials: AJ
authors.lastname: Pinching
authors.forename: J R
authors.initials: JR
authors.lastname: Harris
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D001706:Biopsy; D006801:Humans; D008297:Male; D009894:Opportunistic Infections / Q000150:complications* / Q000473:pathology; D016720:Pneumocystis Infections / Q000150:complications* / Q000473:pathology; D011020:Pneumonia, Pneumocystis / Q000150:complications