[Studies on the triterpenoid constituents of the spores from Ganoderma lucidum karst].
Five compounds were isolated from the ether soluble fraction of the spores of Ganoderma lucidum. On the basis of their chemical properties and spectral data (MS, UV, IR, 1H and 13CNMR), they were identified as 3,7,11,12,15,23-hexaoxo-5 alpha-lanosta-8-en-26-oic acid (I), 3 beta,7 beta-dihydroxy-11,15,23-trioxo-5 alpha-lanosta-8-en-26-oic acid (II), 7 beta-hydroxy-3,11,15,23-tetraoxo-5 alpha-lanosta-8-en-26-oic acid (III), 3,7,11,15,23-pentaoxo-5 alpha-lanosta-8-en-26-oic acid (IV), 24,25,26-trihydroxy-5 alpha-lanosta-7,9 (11)-dien-3-one (V), Compound I is a new natural product, named ganosporeric acid A. Compounds II, III, IV and V were obtained for the first time from the spores of Ganoderma lucidum.
Chen
R Y
RY
Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing.
Yu
D Q
DQ
D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D007810:Lanosterol / Q000031:analogs & derivatives / Q000737:chemistry / Q000302:isolation & purification; D011124:Polyporaceae / Q000737:chemistry*; D013172:Spores, Fungal
D004365:Drugs, Chinese Herbal; C071822:ganosporeric acid A; D007810:Lanosterol