title: Bakery products lower serum cholesterol concentrations in hypercholesterolemic men.
abstract: Several foods rich in water-soluble fiber have documented hypocholesterolemic effects. To determine the cholesterol-lowering effects of high-soluble-fiber intake from refined, wheat-based bakery products, 10 hypercholesterolemic subjects ate a high-carbohydrate, high-fiber control diet in a metabolic ward for 7 d, followed by a diet rich in soluble fiber from bakery products for 21 d. Both control and bakery diets provided 25 g total dietary fiber/d; however, the bakery diet provided 6 g soluble fiber/d more than the control diet. Average serum total cholesterol concentrations stabilized during the control diet and then decreased 6.4% during the bakery diet. Serum low-density-lipoprotein cholesterol decreased 8.5% (P less than 0.05), apolipoprotein B-100 decreased 8.7% (P less than 0.05), and the ratio of apolipoprotein B-100 to apolipoprotein A-I decreased 9.5% (P less than 0.05) during the bakery diet. Results confirm previous reports that a small increase in soluble-fiber intake of approximately 6 g/d modestly decreases atherogenic serum cholesterol concentrations, regardless of fiber source.
authors.affiliation: Metabolic Research Group, University of Kentucky, Lexington.
authors.forename: J W
authors.initials: JW
authors.lastname: Anderson
authors.forename: S
authors.initials: S
authors.lastname: Riddell-Lawrence
authors.forename: T L
authors.initials: TL
authors.lastname: Floor
authors.forename: D W
authors.initials: DW
authors.lastname: Dillon
authors.forename: P R
authors.initials: PR
authors.lastname: Oeltgen
mesh_terms: D000328:Adult; D000368:Aged; D002784:Cholesterol / Q000097:blood*; D003296:Cooking; D004032:Diet; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood* / Q000178:diet therapy; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D009994:Osmolar Concentration; D014908:Triticum
chemical_list: D008055:Lipids; D002784:Cholesterol