[The effect of hemosorption on the kinetics of theophylline in children with bronchial asthma].
Despite complete absorption of theophylline by CKH-4H and phi AC sorbents from the blood of patients one hour after hemosorption the blood drug level reached the values corresponding to the usual level of theophylline elimination. It is concluded that no correction of theophylline dosage is needed during treatment of patients with bronchial asthma by hemosorption, however, the initial blood content of the drug should be between medium and maximum drug level capable of causing therapeutic effect.
Smirnov
D P
DP
Abramzon
M I
MI
D000293:Adolescent; D001249:Asthma / Q000188:drug therapy / Q000628:therapy*; D002648:Child; D003131:Combined Modality Therapy; D006464:Hemoperfusion; D006801:Humans; D013806:Theophylline / Q000008:administration & dosage* / Q000097:blood / Q000627:therapeutic use
D013806:Theophylline
Vliianie gemosorbtsii na kinetiku teofillina u deteĭ s bronkhial'noĭ astmoĭ.