title: [Treatment of patients with corticoid-dependent bronchial asthma by step-by-step intra-pulmonary administration of glucocorticoids].
abstract: The efficacy of a local step-by-step intrapulmonary and systemic administration of glucocorticosteroids (GCS) in 61 patients with corticoid dependent bronchial asthma was studied. A significantly earlier normalization of the basic clinical symptoms of exacerbation of the disease and an improvement of the external respiration function were revealed in the main group of patients, as compared to the controls. The method of a local step-by-step intrapulmonary administration of GCS made it possible to increase the treatment efficacy by bringing down the GCS dosage required to maintain++ remission and excluding complications caused during intrapulmonary injection of drugs to patients with corticoid dependent bronchial asthma.
authors.forename: A V
authors.initials: AV
authors.lastname: Nikitin
authors.forename: V V
authors.initials: VV
authors.lastname: Omeliusik
mesh_terms: D000328:Adult; D001249:Asthma / Q000188:drug therapy*; D001993:Bronchodilator Agents / Q000008:administration & dosage*; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D015552:Injections, Intralesional; D007277:Injections, Jet; D007478:Iontophoresis / Q000379:methods; D008168:Lung / Q000187:drug effects*; D008297:Male; D008775:Methylprednisolone; D008875:Middle Aged
chemical_list: D001993:Bronchodilator Agents; D005938:Glucocorticoids; D008775:Methylprednisolone
vernacular_title: Lechenie bol'nykh kortikozavisimoĭ bronkhial'noĭ astmoĭ poétapnym vnutrilegochnym vvedeniem gliukokortikosteroidov.