Suppression of the defects in rdgB mutants of Escherichia coli K-12 by the cloned purA gene.
A gene suppressing the defects of Escherichia coli rdgB (recA-dependent growth) and recA(Ts) rdgB mutants was cloned. The cloned gene suppresses the hyper-Rec phenotype and the enhanced level of SOS functions in rdgB mutants at the nonpermissive temperature. We identified the cloned gene as purA.
Clyman
J
J
Department of Biological Sciences, State University of New York, Albany 12222.
Cunningham
R P
RP
D003001:Cloning, Molecular; D004591:Electrophoresis, Polyacrylamide Gel; D004926:Escherichia coli / Q000235:genetics* / Q000254:growth & development; D005798:Genes, Bacterial; D016153:Genes, Suppressor; D007700:Kinetics; D009154:Mutation; D010641:Phenotype; D011938:Rec A Recombinases / Q000378:metabolism*; D011995:Recombination, Genetic; D015183:Restriction Mapping; D013014:SOS Response, Genetics; D013696:Temperature
D011938:Rec A Recombinases