[The role of Hantaan virus serotypes in the etiology of hemorrhagic fever with renal syndrome in the Far East of the USSR].
The employment of two serological tests (indirect fluorescence antibody technique and neutralization test) demonstrated the leading role of Hantaan virus serotype 1 strains isolated from field mice in the pattern of the incidence of hemorrhagic fever with renal syndrome (HFRS). Proofs of the etiological importance of strains of serotypes 3 and 5 occurring in brown rats and Cl. rufocanus were obtained. No data on any association of human HFRS cases with strains of serotype 4 isolated from reed voles could be demonstrated.
Astakhova
T I
TI
Slonova
R A
RA
Tkachenko
E A
EA
Bondarenko
A N
AN
Kosoĭ
M E
ME
Kushnarev
E L
EL
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D000918:Antibody Specificity / Q000276:immunology; D006476:Orthohantavirus / Q000145:classification / Q000276:immunology / Q000302:isolation & purification; D006480:Hemorrhagic Fever with Renal Syndrome / Q000453:epidemiology / Q000209:etiology* / Q000276:immunology / Q000382:microbiology; D006801:Humans; D012377:Rodentia / Q000382:microbiology; D016036:Seroepidemiologic Studies; D012703:Serotyping; D012800:Siberia / Q000453:epidemiology
D000914:Antibodies, Viral