Enzyme immunoassay--a method of serological survey of measles vaccination.
Enzyme immunoassay (EIA) for detection of antibodies to measles virus designed in the Moscow Research Institute of Viral Preparations has proved highly sensitive (98%) and specific (100%) as tested in 492 vaccinated children. Comparison of EIA and haemagglutination inhibition (HI) test allowed to determine the cut-off value of the optical density to be equal to 0.1. The serum dilution 1:10 was found appropriate for the screening.
Vedunova
S L
SL
Moscow Research Institute of Viral Preparations, U.S.S.R. Ministry of Health.
Mikheeva
I V
IV
Maltseva
N N
NN
D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007124:Immunoenzyme Techniques; D008458:Measles Vaccine / Q000276:immunology*; D008459:Measles virus / Q000276:immunology*; D014611:Vaccination
D000914:Antibodies, Viral; D008458:Measles Vaccine