Person-to-person transmission of Pseudomonas cepacia between patients with cystic fibrosis.
Ribotyping, a method of strain identification based on analysis of bacterial genomic restriction fragment length polymorphisms, was used to investigate the acquisition of Pseudomonas cepacia by a patient with cystic fibrosis. Analysis of isolates recovered from the index patient and his contacts showed person-to-person transmission of this opportunist organism. This documentation of the transmission of P cepacia from one cystic fibrosis patient to another suggests that measures to limit the acquisition of the pathogen by patients with cystic fibrosis may be worth while.
LiPuma
J J
JJ
Department of Pediatrics, Medical College of Pennsylvania, Philadelphia 19129.
Dasen
S E
SE
Nielson
D W
DW
Stern
R C
RC
Stull
T L
TL
D000328:Adult; D001345:Autoradiography; D003550:Cystic Fibrosis / Q000382:microbiology*; D004269:DNA, Bacterial / Q000032:analysis; D006801:Humans; D012150:Polymorphism, Restriction Fragment Length; D011549:Pseudomonas / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D011552:Pseudomonas Infections / Q000517:prevention & control / Q000635:transmission*; D013183:Sputum / Q000382:microbiology
D004269:DNA, Bacterial