Multiple primary carcinomas as sequelae of treatment of pulmonary tuberculosis with repeated induced pneumothoraces. Case report and review of the literature.
A case is presented of a patient with four separate primary carcinomas (two breast, one thyroid, one multiple skin cancers) arising in areas of the body subject to repeated low-dose radiation exposure during artificial pneumothorax treatment of pulmonary tuberculosis. Evidence for ionizing radiation as the likely common etiologic agent for all four tumors is presented and substantiated by a review of the literature.
Solan
M J
MJ
Department of Radiation Oncology, Hahnemann University, Philadelphia, Pennsylvania 19102.
D001943:Breast Neoplasms / Q000209:etiology*; D002277:Carcinoma / Q000209:etiology; D005260:Female; D005471:Fluoroscopy / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000209:etiology*; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D011031:Pneumothorax, Artificial; D012008:Recurrence; D012878:Skin Neoplasms / Q000209:etiology*; D013964:Thyroid Neoplasms / Q000209:etiology*; D014397:Tuberculosis, Pulmonary / Q000601:surgery*