[The effect of the "37 degrees C--low pH" signal on cells of Yersinia pestis].
It is established that the synthesis of adhesion piles registered by the results of immunoenzyme analysis and immunoblotting starts 90 min after the action on apilated cells of plaque microbe EB-76 of the signal "37 degrees C-low pH" (cultivation at 37 degrees C and acidic pH). Under these conditions a part of cell piline is in a form connected with cells and only inconsiderable part (to 20%) is represented in a form of "classical" piles possessing hemagglutinating activity. It is shown that in first 7h after the interaction of the signal "37 degrees-low pH" synthesis of adhesion piles quantitatively prevails over the synthesis of antigen of the fraction I of plaque microbe.
Vodop'ianov
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D001422:Bacterial Adhesion / Q000502:physiology; D001425:Bacterial Outer Membrane Proteins / Q000032:analysis / Q000378:metabolism; D036781:Fimbriae Proteins; D010861:Fimbriae, Bacterial / Q000737:chemistry / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D013696:Temperature; D013997:Time Factors; D015010:Yersinia pestis / Q000032:analysis / Q000378:metabolism* / Q000472:pathogenicity
D001425:Bacterial Outer Membrane Proteins; D036781:Fimbriae Proteins