Sequence diversity of the 60-kilodalton protein and of a putative 15-kilodalton protein between the trachoma and lymphogranuloma venereum biovars of Chlamydia trachomatis.
DNA from Chlamydia trachomatis serovars L3, C, and E corresponding to the open reading frames of the 60-kDa protein and of a putative 15-kDa protein was sequenced. The open reading frames coding for the 60-kDa protein had 1,641 bp in the three serovars. Compared with the L3 serovar, there were 9 and 11 amino acid changes in the C and E serovars, respectively. The open reading frames corresponding to the putative 15-kDa protein had 450, 456, and 453 bp for the L3, C, and E serovars, respectively. When compared with the L3 serovar, the C and E serovars had 14 and 16 amino acid differences, respectively.
de la Maza
L M
LM
Department of Pathology, University of California, Irvine 92717.
Fielder
T J
TJ
Carlson
E J
EJ
Markoff
B A
BA
Peterson
E M
EM
D000595:Amino Acid Sequence; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D001483:Base Sequence; D002692:Chlamydia trachomatis / Q000235:genetics*; D003001:Cloning, Molecular; D004269:DNA, Bacterial / Q000235:genetics; D014644:Genetic Variation; D008219:Lymphogranuloma Venereum / Q000382:microbiology*; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D014141:Trachoma / Q000382:microbiology*
D001425:Bacterial Outer Membrane Proteins; D004269:DNA, Bacterial; C067561:15K protein, Chlamydia trachomatis; C067562:protein 60K, Chlamydia trachomatis