[Treatment with somatostatin of variceal digestive hemorrhage: a one-year prospective].
Twenty-two patients with variceal bleeding were treated with somatostatin, receiving a bolus of 250 mcg followed by an infusion at a rate of 250 mcg/hour. Bleeding stopped in sixteen patients (72.7%). Definitive control was attained in 13 patients (59.2%). Mortality was 31.8%. Somatostatin was not effective in patients with large varices, jet bleeding and hepatic insufficiency. Only minor side effects were recorded in four patients (18.2%).
Yuguero del Moral
L
L
Sección de Aparato Digestivo, Servicio de Medicina Interna, Hospital General Yagüe, Burgos.
López Morante
A J
AJ
Martín Lorente
J L
JL
Ojeda Giménez
C
C
D000328:Adult; D000368:Aged; D004932:Esophageal and Gastric Varices / Q000150:complications*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013004:Somatostatin / Q000627:therapeutic use*
D013004:Somatostatin