Studies of the teratogenicity of xanthomegnin and viridicatumtoxin in ICR mice.
The myotoxins xanthomegnin and viridicatumtoxin were not teratogenic when administered orally to pregnant ICR mice during the 8-12th and 8-13th days of gestation, respectively. Viridicatumtoxin produced high mortality in mice given 200, 250 or 350 mg/kg of body weight.
Bolin
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Department of Veterinary Pathobiology, School of Veterinary Medicine, Purdue University, West Lafayette, IN 47907.
Carlton
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Peterson
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Grove
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D000818:Animals; D004305:Dose-Response Relationship, Drug; D005260:Female; D051379:Mice; D008813:Mice, Inbred ICR; D009183:Mycotoxins / Q000633:toxicity*; D009285:Naphthoquinones / Q000633:toxicity*; D011247:Pregnancy; D011270:Pregnancy, Animal; D013723:Teratogens
D009183:Mycotoxins; D009285:Naphthoquinones; D013723:Teratogens; C009688:xanthomegnin; C042170:viridicatumtoxin