title: [Results of 6 1/2 years of heart transplantation at Rikshospitalet].
abstract: We discuss our experience from 6 1/2 years of orthotopic heart transplantation at Rikshospitalet (the National Hospital). 112 grafts were performed on 109 patients (19 women and 90 men), mean age 47 years (range 14-63). In the first nine patients the immunosuppressive regimen consisted of cyclosporine A and prednisolone, and in the last 100 azathioprine was added (triple medication). There was no operative mortality. 21 patients died, giving an 81% cumulative survival, with a significantly better prognosis among those who received triple immunosuppressive regimen. The main complications were rejection, infection and arrhythmia. Since our main problem was rejection it is concluded that careful supervision, concentrated on as few cardiologists as possible, and a liberal indication for myocardial biopsy, are decisive for the prognosis.
authors.affiliation: Medisinsk avdeling B, Rikshospitalet, Oslo.
authors.forename: S
authors.initials: S
authors.lastname: Simonsen
authors.forename: O
authors.initials: O
authors.lastname: Geiran
authors.forename: H
authors.initials: H
authors.lastname: Lindberg
authors.forename: A
authors.initials: A
authors.lastname: Foerster
authors.forename: E
authors.initials: E
authors.lastname: Hysing
authors.forename: B
authors.initials: B
authors.lastname: Mohr
authors.forename: K
authors.initials: K
authors.lastname: Forfang
authors.forename: H
authors.initials: H
authors.lastname: Ihlen
authors.forename: T
authors.initials: T
authors.lastname: Frøysaker
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006084:Graft Rejection; D016027:Heart Transplantation / Q000009:adverse effects / Q000379:methods / Q000401:mortality; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009664:Norway; D011379:Prognosis
chemical_list: D007166:Immunosuppressive Agents