A morphometric study of bone surfaces and skin reactions after stimulation with static magnetic fields in rats.
The present investigation was undertaken to measure any bone surface changes after stimulation with orthodontic magnets and, furthermore, to examine the soft tissue in immediate contact with the magnets. Both distal parts of the tibial hind legs in six groups of young rats were fitted with devices holding two orthodontic magnets in the experimental legs and similar devices without magnets in the control legs. The animals were killed after 2, 3, and 4 weeks. Morphometric evaluation showed significant increases in resorbing areas after 3 and 4 weeks. Similarly, a reduction was evident in the number of epithelial cells under the areas where the magnets had been applied. These findings indicate that the stimulation of bone resorption in the present study may have been caused by inhibition of the bone-lining osteoblasts. This proposition is supported by the apparent inhibitory effect of the magnetic fields on epithelial recycling that was seen as a reduced thickness of the epithelium under the magnets. Consequently, static magnetic fields should be used with care in orthodontic practice until a more complete understanding of their mechanism of action has been established.
Linder-Aronson
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Department of Orthodontics, Karolinska Institutet, Stockholm, Sweden.
Lindskog
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D000818:Animals; D001862:Bone Resorption; D004848:Epithelium / Q000528:radiation effects; D008280:Magnetics; D008297:Male; D009967:Orthodontic Appliances; D051381:Rats; D011919:Rats, Inbred Strains; D012867:Skin / Q000528:radiation effects; D013977:Tibia / Q000528:radiation effects