title: [Study of the APUD cells of the gastric mucosa].
abstract: The results of an histochemical and microscopic study of the APUD cells carried on gastric biopsies are reported. Endocrine cell hyperplasia, microscopically detected, was particularly evident in atrophic gastritis (type A chronic gastritis) and adenomas. The presence of the APUD cells confirmed by electronmicroscopy, which revealed granules of 200 NM with a central nucleus and a membrane-separating electron-lucent ring, gives a further contribution to the hypothesis of a possible association between endocrine cell hyperplasia and intestinal metaplasia.
authors.affiliation: Istituto di Chirurgia Generale, Università degli Studi di Messina.
authors.forename: G M
authors.initials: GM
authors.lastname: Sampiero
authors.forename: G
authors.initials: G
authors.lastname: Papalia
authors.forename: R
authors.initials: R
authors.lastname: Caruso
authors.forename: L
authors.initials: L
authors.lastname: Rando
authors.forename: A G
authors.initials: AG
authors.lastname: Rizzo
authors.forename: B
authors.initials: B
authors.lastname: Cuffari
authors.forename: B
authors.initials: B
authors.lastname: Lo Forti
authors.forename: N
authors.initials: N
authors.lastname: Di Pietro
authors.forename: S
authors.initials: S
authors.lastname: Gorgone
authors.forename: M
authors.initials: M
authors.lastname: Barbuscia
mesh_terms: D001078:APUD Cells; D000236:Adenoma / Q000473:pathology; D000328:Adult; D000368:Aged; D001706:Biopsy; D002908:Chronic Disease; D004415:Dyspepsia / Q000473:pathology; D005753:Gastric Mucosa / Q000166:cytology*; D005757:Gastritis, Atrophic / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D008854:Microscopy, Electron; D008875:Middle Aged; D011127:Polyps / Q000473:pathology; D013274:Stomach Neoplasms / Q000473:pathology; D013276:Stomach Ulcer / Q000473:pathology