Gaucher's disease complicated by bleeding esophageal varices and colonic infiltration by Gaucher cells.
We report a 10-yr-old child with Gaucher's disease who developed upper gastrointestinal bleeding from esophageal varices, as well as hemorrhage from a colonic polyp infiltrated with Gaucher cells. Both the varices and polyp were treated endoscopically, and the outcome was successful. Although gastrointestinal hemorrhage due to portal hypertension is considered a rare complication of Gaucher's disease, colonic infiltration with Gaucher cells has not been recognized previously.
Henderson
J M
JM
Department of Medicine, University of Kentucky Medical Center, Lexington.
Gilinsky
N H
NH
Lee
E Y
EY
Greenwood
M F
MF
D001706:Biopsy; D002648:Child; D003106:Colon / Q000473:pathology; D003111:Colonic Polyps / Q000150:complications* / Q000473:pathology; D004932:Esophageal and Gastric Varices / Q000150:complications*; D005260:Female; D005776:Gaucher Disease / Q000150:complications* / Q000473:pathology; D006396:Hematemesis / Q000209:etiology*; D006801:Humans; D008099:Liver / Q000473:pathology; D008551:Melena / Q000209:etiology*