title: Echocardiography as a tool for determining the incidence of congenital heart disease in newborn babies: a pilot study in Hong Kong.
abstract: We studied, with echocardiography as the main tool, the incidence of congenital heart disease in newborn babies in Hong Kong. The population examined was the 20,928 babies who were born alive in the Prince of Wales Hospital from January 1987 to December 1989. All had a thorough physical examination by a paediatrician after birth, and an estimated 95% of the babies who were discharged from hospital received another routine physical examination at one of the five local Maternal and Child Health Centres within two months of birth. All babies with either suspected congenital heart disease or multiple congenital abnormalities were referred to the paediatric cardiologists in the Prince of Wales Hospital for further cardiovascular assessment that included echocardiographic examination. In all, 492 babies had Doppler and cross-sectional echocardiographic studies. Various abnormalities of the cardiovascular system were diagnosed in 216 babies. Almost all the babies who died within two months of life underwent autopsy. This proved the presence of congenital cardiac malformations in 15 babies, of whom 10 had correct echocardiographic diagnoses during life. One had a patent arterial duct which was missed by the echocardiography. The other four babies did not have echocardiographic examination while alive, either because of early death or absence of clinical suspicion. In total, congenital cardiac malformations were confirmed in 221 babies by echocardiographic examination and autopsy. Excluding 82 premature babies with patency of the arterial duct, and 6 babies with transient tricuspid regurgitation, there were 133 cases of structural cardiac malformation in the studied population, giving an incidence of 6.35 per thousand live births.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong.
authors.forename: R Y
authors.initials: RY
authors.lastname: Sung
authors.forename: L Y
authors.initials: LY
authors.lastname: So
authors.forename: H K
authors.initials: HK
authors.lastname: Ng
authors.forename: J K
authors.initials: JK
authors.lastname: Ho
authors.forename: T F
authors.initials: TF
authors.lastname: Fok
mesh_terms: D004452:Echocardiography / Q000706:statistics & numerical data*; D015150:Echocardiography, Doppler / Q000706:statistics & numerical data*; D005260:Female; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging / Q000453:epidemiology*; D006723:Hong Kong / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D008297:Male; D015997:Neonatal Screening; D010865:Pilot Projects