CD71 phenotype and the value of gallium imaging in lymphomas.
Tumor cells of 14 cases of non-Hodgkin lymphomas and 2 cases of Hodgkin disease were tested for the presence of the transferrin receptor (CD71) by flow cytofluorimetry before 67gallium imaging. It appeared that expression of CD71 phenotype was closely related to the positivity of gallium scan before therapy. We feel that this test is able to predict the avidity for 67gallium and the clinical implications are discussed.
Feremans
W
W
Department of Internal Medicine, Cliniques Universitaires de Bruxelles, Hôpital Erasme, Belgium.
Bujan
W
W
Neve
P
P
Delville
J P
JP
Schandene
L
L
D001853:Bone Marrow / Q000000981:diagnostic imaging / Q000276:immunology / Q000648:ultrastructure; D005434:Flow Cytometry / Q000379:methods; D005710:Gallium Radioisotopes; D006689:Hodgkin Disease / Q000000981:diagnostic imaging / Q000235:genetics* / Q000276:immunology; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000276:immunology / Q000648:ultrastructure; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging / Q000235:genetics* / Q000276:immunology; D010641:Phenotype; D011877:Radionuclide Imaging; D011990:Receptors, Transferrin / Q000235:genetics*; D014057:Tomography, X-Ray Computed
D005710:Gallium Radioisotopes; D011990:Receptors, Transferrin