Low plasma iron status and akathisia.
Thirty patients were examined to test the hypothesis that a depletion of iron levels is associated with symptoms of akathisia. Fifteen akathisic patients were pair-matched with 15 non-akathisic patients. Plasma ferritin levels were significantly decreased in the akathisic patients, and there was a significant inverse correlation between plasma iron levels and akathisia rating. In addition, akathisia ratings were found to be correlated with a scale measuring symptoms of tardive dyskinesia.
Barton
A
A
Department of Mental Health, University of Aberdeen, Foresterhill.
Bowie
J
J
Ebmeier
K
K
D000328:Adult; D017109:Akathisia, Drug-Induced; D000747:Anemia, Hypochromic / Q000097:blood*; D014150:Antipsychotic Agents / Q000009:adverse effects*; D002352:Carrier Proteins / Q000097:blood; D004305:Dose-Response Relationship, Drug; D004409:Dyskinesia, Drug-Induced / Q000097:blood / Q000175:diagnosis; D005260:Female; D005293:Ferritins / Q000097:blood; D006801:Humans; D007501:Iron / Q000097:blood*; D033862:Iron-Binding Proteins; D008297:Male; D008875:Middle Aged; D011595:Psychomotor Agitation / Q000097:blood / Q000175:diagnosis; D012307:Risk Factors; D033863:Transferrin-Binding Proteins
D014150:Antipsychotic Agents; D002352:Carrier Proteins; D033862:Iron-Binding Proteins; D033863:Transferrin-Binding Proteins; D005293:Ferritins; D007501:Iron