Peptides incorporating electrophilic glutamine analogues as potential transglutaminase inhibitors.
Doyle
P M
PM
Department of Medicinal Chemistry, Wellcome Research Laboratories, Beckenham, Kent, U.K.
Harris
C J
CJ
Carter
K R
KR
Simpkin
D S
DS
Bailey-Smith
P
P
Stone
D
D
Russell
L
L
Blackwell
G J
GJ
D000595:Amino Acid Sequence; D005973:Glutamine / Q000031:analogs & derivatives; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D008969:Molecular Sequence Data; D010455:Peptides / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D013379:Substrate Specificity; D011503:Transglutaminases / Q000037:antagonists & inhibitors* / Q000378:metabolism
D010455:Peptides; D005973:Glutamine; D011503:Transglutaminases