title: Quinoxalinediones as excitatory amino acid antagonists in the vertebrate central nervous system.
authors.affiliation: Division of Physiology, School of Biomedical Sciences, Marischal College, Aberdeen, U.K.
authors.forename: S N
authors.initials: SN
authors.lastname: Davies
authors.forename: G L
authors.initials: GL
authors.lastname: Collingridge
mesh_terms: D018750:6-Cyano-7-nitroquinoxaline-2,3-dione; D000818:Animals; D001224:Aspartic Acid / Q000037:antagonists & inhibitors; D001667:Binding, Competitive; D002490:Central Nervous System / Q000502:physiology*; D018691:Excitatory Amino Acid Antagonists; D018698:Glutamic Acid; D006624:Hippocampus / Q000187:drug effects / Q000502:physiology; D006801:Humans; D007608:Kainic Acid / Q000037:antagonists & inhibitors; D008564:Membrane Potentials / Q000187:drug effects; D016202:N-Methylaspartate / Q000037:antagonists & inhibitors; D011810:Quinoxalines / Q000494:pharmacology*; D051381:Rats; D018091:Receptors, AMPA; D017470:Receptors, Glutamate; D016194:Receptors, N-Methyl-D-Aspartate / Q000187:drug effects* / Q000502:physiology; D017981:Receptors, Neurotransmitter / Q000187:drug effects* / Q000502:physiology; D015398:Signal Transduction / Q000187:drug effects; D013116:Spinal Cord / Q000187:drug effects / Q000502:physiology; D013329:Structure-Activity Relationship; D014714:Vertebrates / Q000502:physiology
chemical_list: D018691:Excitatory Amino Acid Antagonists; D011810:Quinoxalines; D018091:Receptors, AMPA; D017470:Receptors, Glutamate; D016194:Receptors, N-Methyl-D-Aspartate; D017981:Receptors, Neurotransmitter; D001224:Aspartic Acid; D018698:Glutamic Acid; C056723:FG 9041; D016202:N-Methylaspartate; D018750:6-Cyano-7-nitroquinoxaline-2,3-dione; D007608:Kainic Acid