[An experimental validation of the endolymphatic administration of pharmacological preparations for stimulating intestinal peristalsis in emergency surgery on the abdominal cavity].
Experiments were conducted on 75 rabbits to study the efficacy of endolymphatic administration of aceclidine, obsidan, and cerucal for stimulation of the intestine in its experimental paresis. The stimulating effect of the pharmacological agents was found to be of a longer duration in endolymphatic that in intravenous administration. This allowed endolymphatic pharmacological stimulation of the intestine to be suggested for the use in abdominal surgery.
Dzheĭranov
F D
FD
Riabtsev
V G
VG
Myslovatyĭ
B S
BS
Mezvrishvili
G O
GO
Masiukevich
A V
AV
D000005:Abdomen / Q000601:surgery*; D000818:Animals; D004353:Drug Evaluation, Preclinical; D004630:Emergencies; D005260:Female; D005769:Gastrointestinal Motility / Q000187:drug effects*; D007272:Injections, Intralymphatic; D007275:Injections, Intravenous; D007430:Intraoperative Care / Q000379:methods*; D008297:Male; D008787:Metoclopramide / Q000008:administration & dosage*; D011433:Propranolol / Q000008:administration & dosage*; D011812:Quinuclidines / Q000008:administration & dosage*; D011817:Rabbits; D013268:Stimulation, Chemical
D011812:Quinuclidines; D011433:Propranolol; D008787:Metoclopramide