Management of arginine monohydrochloride extravasation in the forearm.
We initially observed our patient, who had subcutaneous arginine monohydrochloride extravasation in the volar forearm, until his wound demarcation was complete. After wound demarcation, we proceeded with debridement and partial-thickness skin grafting. Upper extremity function was totally normal 3 months after this therapy. This is the first case report in the literature that describes a child with an arginine monohydrochloride-induced extravasation necrosis.
Baker
G L
GL
Division of Plastic and Reconstructive Surgery, University of Tennessee, Chattanooga.
Franklin
J D
JD
D000592:Amino Acid Metabolism, Inborn Errors / Q000188:drug therapy; D001120:Arginine / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D001124:Argininosuccinate Synthase / Q000172:deficiency; D002648:Child; D003646:Debridement; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000601:surgery*; D005542:Forearm; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D009336:Necrosis; D012867:Skin / Q000473:pathology; D016038:Skin Transplantation
D001120:Arginine; D001124:Argininosuccinate Synthase