Clustering of fungal allergen-specific IgE antibody responses in allergic subjects.
Statistical analysis of specific IgE immune responses to a panel of nine allergens from 2,094 patients demonstrated significant clustering between Aspergillus fumigatus, Alternaria alternata, and Cladosporium herbarum, not explained by crossreactive elements. This may represent a linked, high responder status to these fungal antigens in the allergic population.
Potter
P C
PC
Department of Clinical Science and Immunology, Allergy Clinic, University of Cape Town, South Africa.
Juritz
J
J
Little
F
F
McCaldin
M
M
Dowdle
E B
EB
D000328:Adult; D000485:Allergens / Q000276:immunology*; D000528:Alternaria / Q000276:immunology; D000818:Animals; D000908:Antibodies, Fungal / Q000097:blood; D001232:Aspergillus fumigatus / Q000276:immunology; D002415:Cats; D002648:Child; D002963:Cladosporium / Q000276:immunology; D016000:Cluster Analysis; D003429:Cross Reactions; D004285:Dogs; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology / Q000276:immunology*; D007073:Immunoglobulin E / Q000032:analysis*; D003904:Mitosporic Fungi / Q000276:immunology*; D011852:Radioallergosorbent Test
D000485:Allergens; D000908:Antibodies, Fungal; D007073:Immunoglobulin E