Molecular resolution imaging of polyglucose by scanning tunneling microscopy.
We have obtained atomic resolution images of poly-alpha-D-glucose by scanning tunneling microscopy. The oxygen atoms near the scanning tip were imaged, but the carbon and hydrogen atoms were not visible. The measured inter-atomic distances are consistent with the molecular structure of poly-alpha-D-glucose deduced from chemical and X-ray diffraction studies. The results also demonstrate that is is feasible to image surface atomic structures of a relatively thick non-conducting specimen, suggesting that the technique may be applied to the study of other macromolecules of biological importance.
Yang
J
J
Department of Physiology, University of Virginia, Charlottesville 22908.
Takeyasu
K
K
Somlyo
A P
AP
Shao
Z F
ZF
D000818:Animals; D005947:Glucose / Q000737:chemistry; D008112:Liver Glycogen; D016252:Microscopy, Scanning Tunneling / Q000379:methods*; D015394:Molecular Structure; D011817:Rabbits
D008112:Liver Glycogen; D005947:Glucose