title: Pregnancy and complicated familial Mediterranean fever.
abstract: Familial Mediterranean Fever (FMF) is an inherited disease, closely following the pattern of autosomal recessive inheritance. Amyloidosis is the most severe complication of the disease. The prevalence of pregnancy loss in women with FMF is considered to be high. There is no information to support the possibility of increase risk of late pregnancy complications or change in the natural course of the disease. Two cases are presented with complicated FMF. One case with proved amyloidosis and the second patient with ascites. Pregnancy and neonatal outcome were uneventful in both. No further deterioration in the systemic disease occurred.
authors.affiliation: Department of Obstetrics and Gynecology, Central Emek Hospital, Afula, Israel.
authors.forename: Y
authors.initials: Y
authors.lastname: Shimoni
authors.forename: E
authors.initials: E
authors.lastname: Shalev
mesh_terms: D000328:Adult; D000686:Amyloidosis / Q000209:etiology; D001201:Ascites / Q000209:etiology; D003078:Colchicine / Q000009:adverse effects / Q000627:therapeutic use; D010505:Familial Mediterranean Fever / Q000150:complications / Q000188:drug therapy; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000473:pathology
chemical_list: D003078:Colchicine