title: Chromosome assignment of four RAS-related RAB genes.
abstract: The human RAB genes share structural and biochemical properties with the RAS gene superfamily. The encoded RAB proteins show 38 to 75% amino acid identity with the yeast YPT1 and SEC4 gene products. We used four human RAB-cDNAs, RAB3B, RAB4, RAB5 and RAB6, to map the corresponding genes on human chromosomes. These genes were assigned to 1p32-p31, 1q42-q43, 3p24-p22 and 2q14-q21, respectively, by in situ hybridization.
authors.affiliation: INSERM U.301, Institut de Génétique Moléculaire, Paris, France.
authors.forename: M F
authors.initials: MF
authors.lastname: Rousseau-Merck
authors.forename: A
authors.initials: A
authors.lastname: Zahraoui
authors.forename: N
authors.initials: N
authors.lastname: Touchot
authors.forename: A
authors.initials: A
authors.lastname: Tavitian
authors.forename: R
authors.initials: R
authors.lastname: Berger
mesh_terms: D002871:Chromosome Banding; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D002888:Chromosomes, Human, Pair 19; D011905:Genes, ras; D006801:Humans; D005810:Multigene Family; D011519:Proto-Oncogenes