title: In vivo measurements of ultrasonic beam distortion in the breast.
abstract: The phase aberrations encountered by ultrasonic pulses propagating through breast tissue in twenty-two female volunteers were measured. The experiments were designed to assess the impact of these aberrations on clinical ultrasonic image quality for a variety of transducer and imaging geometries. The phase aberration profiles of a given patient were correlated with the amount of parenchymal tissue determined from that patient's mammogram. These data are useful in assessing the image quality achievable with conventional ultrasonic imaging systems, and the potential application of adaptive ultrasonic imaging systems. The results indicate that phase aberrations significantly degrade breast image quality for typical transducer frequencies and sizes.
authors.affiliation: Department of Biomedical Engineering, Duke University, Durham, NC 27706.
authors.forename: G E
authors.initials: GE
authors.lastname: Trahey
authors.forename: P D
authors.initials: PD
authors.lastname: Freiburger
authors.forename: L F
authors.initials: LF
authors.lastname: Nock
authors.forename: D C
authors.initials: DC
authors.lastname: Sullivan
mesh_terms: D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008722:Methods; D014465:Ultrasonics; D014463:Ultrasonography