title: Dry instant blood typing plate for bedside use.
abstract: A monoclonal antibody-derived, dry blood grouping plate, based upon the simple disaccharide, trehalose, is described that is indefinitely stable at room temperature and was found to have a 99.8% accuracy when tested against a standard semiautomated assay. This plate can be used by personnel with no specific training to check the recorded A,B,O, and Rhesus blood type of potential transfusion recipients in the field and at the bedside. Trehalose-based reagents may be important for bedside testing and in developing countries where refrigeration is unreliable.
authors.affiliation: Quadrant Research Foundation, Cambridge Research Laboratories, UK.
authors.forename: D
authors.initials: D
authors.lastname: Blakeley
authors.forename: B
authors.initials: B
authors.lastname: Tolliday
authors.forename: C
authors.initials: C
authors.lastname: Colaco
authors.forename: B
authors.initials: B
authors.lastname: Roser
mesh_terms: D000372:Agglutination Tests; D000911:Antibodies, Monoclonal; D001788:Blood Grouping and Crossmatching / Q000295:instrumentation* / Q000379:methods; D003906:Developing Countries; D004356:Drug Storage / Q000379:methods; D005069:Evaluation Studies as Topic; D006801:Humans; D007075:Immunoglobulin M; D013997:Time Factors; D014199:Trehalose
chemical_list: D000911:Antibodies, Monoclonal; D007075:Immunoglobulin M; D014199:Trehalose