title: Knee hyaline cartilage evaluated with MR imaging: a cadaveric study involving multiple imaging sequences and intraarticular injection of gadolinium and saline solution.
abstract: Magnetic resonance (MR) imaging of cadaveric knees was performed to determine optimal sequences for visualization of hyaline cartilage. Six fresh-frozen cadaveric knees were imaged with a 1.5-T imager by means of standard and hybrid fat suppression (HFS) spin-echo techniques, with and without intraarticular injection of saline solution and gadopentetate dimeglumine. The knees then were sectioned at 4-mm intervals. Both the real and the imaged cartilage thicknesses were measured. Areas of cartilage thinning and focal defects seen in the cadaveric sections were most accurately matched, in both the presence and the absence of intraarticular saline solution simulating joint fluid, by images obtained with the T1-weighted HFS sequences. Accurate imaging of hyaline cartilage thickness with differentiation of cartilage from fluid was possible routinely. Standard and HFS spin-echo images obtained after intraarticular injection of gadopentetate dimeglumine depicted cartilage less accurately than HFS sequences either with or without saline injection. MR imaging with T1-weighted HFS sequences provided superior visualization of cartilage, enabling accurate measurements of cartilage thickness and differentiation of cartilage from saline solution simulating joint fluid.
authors.affiliation: Department of Radiology, Veterans Administration Medical Center, San Diego, CA 92161.
authors.forename: V P
authors.initials: VP
authors.lastname: Chandnani
authors.forename: C
authors.initials: C
authors.lastname: Ho
authors.forename: P
authors.initials: P
authors.lastname: Chu
authors.forename: D
authors.initials: D
authors.lastname: Trudell
authors.forename: D
authors.initials: D
authors.lastname: Resnick
mesh_terms: D002358:Cartilage, Articular / Q000033:anatomy & histology*; D003287:Contrast Media; D019786:Gadolinium DTPA; D006801:Humans; D066298:In Vitro Techniques; D007719:Knee Joint / Q000033:anatomy & histology*; D008279:Magnetic Resonance Imaging; D009942:Organometallic Compounds; D004369:Pentetic Acid; D012965:Sodium Chloride / Q000008:administration & dosage
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D012965:Sodium Chloride; D004369:Pentetic Acid; D019786:Gadolinium DTPA