title: Late metastases of cutaneous melanoma: case report and literature review.
abstract: The development of delayed metastases, although rare, is well documented in patients with invasive cutaneous melanoma. Only 24 cases, including ours, are clearly documented in the literature. We describe a 56-year-old woman who had an acral lentiginous melanoma of the right hand (thickness 1.2 mm). Thirteen years after excision and postoperative irradiation, a subcutaneous metastasis developed in the right arm. One year later the patient died with disseminated bone metastases. This case, as with most of those with delayed metastases, has typical features: female sex; location at a site other than the back, arm, neck, or scalp; and primary tumor thickness between 1.2 and 2.5 mm.
authors.affiliation: Department of Pathology, Istituti Ospedalieri di Trento, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Boi
authors.forename: M
authors.initials: M
authors.lastname: Amichetti
mesh_terms: D001132:Arm; D001859:Bone Neoplasms / Q000556:secondary; D005260:Female; D006225:Hand; D006801:Humans; D008545:Melanoma / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D008875:Middle Aged; D012878:Skin Neoplasms / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D013997:Time Factors