Microbiological study of HIV-related periodontitis.
The subgingival microbiota in 14 persons with HIV-periodontitis was examined. Subgingival plaque samples were collected with paper points, transported in VMGA III, and plated on anaerobic enriched brucella blood agar and various selective media. HIV-periodontitis sites revealed Actinobacillus actinomycetemcomitans, Wolinella recta, Peptostreptococcus micros, and Bacteroides intermedius, each averaging 7% to 16% of the cultivable subgingival flora in positive patients. High levels of spirochetes also were detected in diseased sites with phase-contrast microscopy. Low levels of Candida albicans or enteric Gram-negative rods were recovered in the subgingival flora in 7 HIV-periodontitis patients or Bacteroides fragilis, Fusobacterium necrophorum, Fusobacterium varium, and Eubacterium aerofaciens were recovered in 8 patients. These findings suggest that the major components of the subgingival microbial flora in HIV-periodontitis are similar to those associated with adult periodontitis in systemically healthy persons. However, HIV-periodontitis lesions also may contain organisms which are rarely found in common types of periodontitis. The etiological significance of specific periodontal organisms in HIV-periodontitis awaits further longitudinal study.
Rams
T E
TE
Department of Periodontics, University of Pennsylvania School of Dental Medicine, Philadelphia.
Andriolo
M
M
Feik
D
D
Abel
S N
SN
McGivern
T M
TM
Slots
J
J
D000386:AIDS-Related Complex / Q000150:complications; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000188:Actinobacillus / Q000302:isolation & purification; D000328:Adult; D001419:Bacteria / Q000145:classification / Q000302:isolation & purification*; D001438:Bacteroidaceae / Q000302:isolation & purification; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006679:HIV Seropositivity; D006801:Humans; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000150:complications / Q000382:microbiology*