Diffuse panbronchiolitis in North America. Report of three cases and review of the literature.
Diffuse panbronchiolitis is a disease largely restricted geographically to Japan. It is manifested clinically by an insidious onset of dyspnea, cough, and production of mucopurulent sputum. Histologically it is characterized by a suppurative bronchiolitis involving primarily the respiratory and terminal bronchioles with subsequent progression to bronchiolectasis. Pulmonary function tests show a mixed obstructive-restrictive pattern. This report presents two cases occurring in white patients and one in an Oriental immigrant to Canada.
Randhawa
P
P
Department of Pathology, Presbyterian University Hospital, Pittsburgh, PA 15213.
Hoagland
M H
MH
Yousem
S A
SA
D000328:Adult; D044466:Asian People; D001980:Bronchi / Q000473:pathology / Q000503:physiopathology; D001988:Bronchiolitis / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009656:North America / Q000453:epidemiology; D011659:Pulmonary Gas Exchange / Q000502:physiology; D044465:White People