[Changes in prostaglandin levels in the blood of patients with various forms of chronic colitis before and after treatment].
Plasma prostaglandins have been studied in 306 patients with chronic nonspecific ulcerative colitis. These were found elevated and related to the disease gravity. Treatment succeeded in normalizing prostaglandin, concentrations only in mild ulcerative colitis. In catarrhal pancolitis PGE levels moderately increased before treatment returned to normal at the end of it. In spastic colon pretreatment lack of PGF2 alpha persisted. Evaluation of plasma prostaglandins can serve an additional diagnostic procedure to improve pathogenetic therapy of chronic colitis.
Shafer
N P
NP
Askarov
U A
UA
D000293:Adolescent; D000328:Adult; D002908:Chronic Disease; D003092:Colitis / Q000097:blood* / Q000175:diagnosis / Q000188:drug therapy; D015237:Dinoprost / Q000097:blood*; D006801:Humans; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D011458:Prostaglandins E / Q000097:blood*; D012720:Severity of Illness Index; D012460:Sulfasalazine / Q000627:therapeutic use
D011458:Prostaglandins E; D012460:Sulfasalazine; D011239:Prednisolone; D015237:Dinoprost