Cloning of a Chinese hamster protein homologous to the mouse t-complex protein TCP-1: structural similarity to the ubiquitous 'chaperonin' family of heat-shock proteins.
The complete cDNA sequence of a Chinese hamster ovary cell protein, homologous to a mouse t-complex protein, TCP-1, has been determined. The deduced amino acid sequences of the mouse/Chinese hamster TCP-1 proteins exhibit significant identity to the 60-65 kDa heat shock 'chaperonin' family of proteins present in prokaryotes and in the eukaryotic cell organelles.
Ahmad
S
S
Department of Biochemistry, McMaster University, Hamilton, Ontario, Canada.
Gupta
R S
RS
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D018833:Chaperonins; D003001:Cloning, Molecular; D006224:Cricetinae; D006360:Heat-Shock Proteins / Q000235:genetics*; D047908:Intracellular Signaling Peptides and Proteins; D051379:Mice; D008869:Microtubule-Associated Proteins; D008969:Molecular Sequence Data; D005810:Multigene Family; D009687:Nuclear Proteins / Q000235:genetics*; D011506:Proteins / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D044767:Ubiquitin-Protein Ligases; D056427:t-Complex Genome Region
D006360:Heat-Shock Proteins; D047908:Intracellular Signaling Peptides and Proteins; D008869:Microtubule-Associated Proteins; D009687:Nuclear Proteins; D011506:Proteins; C116196:PPP1R11 protein, human; D044767:Ubiquitin-Protein Ligases; D018833:Chaperonins