title: Endoderm-specific expression of the Drosophila mex1 gene.
abstract: The Drosophila mex1 gene is one of several genes clustered within a 10-kb interval of polytene region 71CD that includes the ecdysone-regulated Eip28/29 gene. mex1 is expressed in several developmental stages, with gene transcripts accumulating initially in 9- to 12-hr embryos. During embryogenesis, mex1 exhibits an endoderm-specific pattern of expression. mex1 transcripts are first detected in the anterior and posterior midgut primordia of stage 12 embryos; subsequently, mex1 mRNA accumulates solely in the differentiating embryonic midgut. DNA sequence analysis reveals that the mex1 gene encodes an unusual cysteine-rich polypeptide.
authors.affiliation: Department of Biochemistry and Molecular Biology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
authors.forename: R A
authors.initials: RA
authors.lastname: Schulz
authors.forename: X
authors.initials: X
authors.lastname: Xie
authors.forename: A J
authors.initials: AJ
authors.lastname: Andres
authors.forename: S
authors.initials: S
authors.lastname: Galewsky
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004330:Drosophila / Q000196:embryology / Q000235:genetics*; D004707:Endoderm / Q000378:metabolism*; D005786:Gene Expression Regulation; D008969:Molecular Sequence Data; D005810:Multigene Family; D009693:Nucleic Acid Hybridization; D009928:Organ Specificity / Q000235:genetics; D015183:Restriction Mapping; D014158:Transcription, Genetic