[Results of a 10-year prospective study of patients with ischemic heart disease].
The paper analyses the results of a 10-year prospective study of 396 patients with coronary heart disease concurrent with stable angina pectoris of different functional classes without serious concomitant diseases. In all the patients. coronary angiography revealed stenosis of one-to-three great coronary arteries and ventriculography showed no severe abnormalities in left ventricular contractility. A long-term drug therapy promoted not only improvement of the clinical status in most patients, but maintenance of work capacity and increase of their lifespan. The annual mortality rate was 3.0%, the incidence of nonfatal myocardial infarction was 5.9%. Repeated coronary angiography indicated that progression of coronary atherosclerosis was accompanied by a clinical deterioration in the patients' health and a decrease in exercise tolerance.
Iurenev
A P
AP
Lediashova
G A
GA
Lupanov
V P
VP
Rubanovich
A I
AI
Zhukova
I M
IM
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D000792:Angiography; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D017023:Coronary Angiography; D003327:Coronary Disease / Q000175:diagnosis / Q000188:drug therapy* / Q000401:mortality; D004562:Electrocardiography; D005080:Exercise Test; D006801:Humans; D008297:Male; D008875:Middle Aged; D009031:Moscow; D009566:Nitrates / Q000627:therapeutic use; D011446:Prospective Studies; D013997:Time Factors
D000319:Adrenergic beta-Antagonists; D002121:Calcium Channel Blockers; D009566:Nitrates