title: New surgical approach to complicated gastroesophageal reflux disease: transthoracic parietal cell vagotomy.
abstract: Surgical treatment of peptic stricture of the esophagus associated with columnar (Barrett) metaplasia can be a difficult problem. Collis-Nissen fundoplication restores an intraabdominal antireflux barrier for most cases of peptic stricture; however, 20% of patients may have persistence of pathological acid reflux. By reducing acidity of postoperative reflux, parietal cell vagotomy may complement nonresectional surgical results for Barrett stricture.
authors.affiliation: Division of Cardiothoracic Surgery, University of Missouri School of Medicine, Columbia.
authors.forename: R J
authors.initials: RJ
authors.lastname: Landreneau
authors.forename: J B
authors.initials: JB
authors.lastname: Marshall
authors.forename: R N
authors.initials: RN
authors.lastname: McClelland
authors.forename: J J
authors.initials: JJ
authors.lastname: Curtis
authors.forename: J A
authors.initials: JA
authors.lastname: Johnson
authors.forename: S R
authors.initials: SR
authors.lastname: Hazelrigg
mesh_terms: D004940:Esophageal Stenosis / Q000473:pathology / Q000601:surgery*; D005764:Gastroesophageal Reflux / Q000601:surgery*; D006801:Humans; D008297:Male; D008679:Metaplasia; D008875:Middle Aged; D014629:Vagotomy, Proximal Gastric / Q000379:methods*