[Judicious use of anorectics].
Physicians treating adipose patients often hesitate to include drugs. Considering new developments in obesity research and drug-therapy, this attitude should be discussed. Anorectics of the amphetamine-group and analogues (derivates) react with the noradrenergic system and induce appetite-suppression. Fenfluramine in the d-1 configuration and isomeric dextro-rotation influence release of serotonin, reduce intake of food and increase sensation of saturation. In addition, various eating behavior disorders like nibbling and addiction to sweets are discussed. Use of Dextro-fenfluramine for these special situations is discussed as well as its side effects, duration of drug intake and form of application. Importance of concomitant therapeutic means like hypocaloric diet and personal attendance are emphasized.
Laurent-Jaccard
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Policlinique médicale universitaire, Lausanne.
D001067:Appetite Depressants / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003376:Counseling; D004038:Diet, Reducing; D005277:Fenfluramine / Q000627:therapeutic use; D006801:Humans; D007536:Isomerism; D009765:Obesity / Q000188:drug therapy* / Q000628:therapy
D001067:Appetite Depressants; D005277:Fenfluramine