title: Solitary, isolated metastasis from Ewing's sarcoma to the brain: case report.
abstract: We report a case of a 30-year-old woman who developed an intraparenchymal cerebral metastasis from a Ewing's sarcoma of the chest wall diagnosed and treated 3 years earlier and in apparent remission at the time of the neurological presentation (seizures). The case was complicated by a spontaneous preoperative intratumoral hemorrhage that occurred the morning of the scheduled surgical resection and caused a left dense hemiparesis. The tumor and the hematoma were removed. The patient improved after surgical intervention and a postoperative course of cranial irradiation followed by systemic chemotherapy was given. Nineteen months after treatment the patient remains disease-free from the clinical and radiological standpoint.
authors.affiliation: Department of Neurological Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
authors.forename: A
authors.initials: A
authors.lastname: Olivi
authors.forename: R C
authors.initials: RC
authors.lastname: Donehower
authors.forename: R B
authors.initials: RB
authors.lastname: Mann
authors.forename: H
authors.initials: H
authors.lastname: Brem
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000473:pathology; D001932:Brain Neoplasms / Q000150:complications / Q000556:secondary* / Q000628:therapy; D002543:Cerebral Hemorrhage / Q000209:etiology / Q000601:surgery; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D005260:Female; D006801:Humans; D012074:Remission Induction; D012272:Ribs; D012512:Sarcoma, Ewing / Q000150:complications / Q000556:secondary* / Q000628:therapy