[The participation of cholinergic structures at different levels in shaping the immediate adaptation of the pancreas to food quality in ontogeny].
The experiments on rats showed that the urgent enzymatic adaptations of the pancreas to the quality of food have not been inherent, but have been created in the ontogeny. These adaptations are usually absent during transition to the definitive feeding (23rd day of life). Adaptation for protein stimulant appears in the moment of taking away of mother (30th day of life) and becomes persistent for protein and fat stimulants by the 90th day of life (adult rats). The blockade of different levels' cholinergic structures prevents the normal development of urgent specific pancreas adaptations in all investigated ages.
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D000222:Adaptation, Physiological / Q000187:drug effects / Q000502:physiology*; D000375:Aging / Q000187:drug effects / Q000502:physiology*; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D001535:Benactyzine / Q000494:pharmacology; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D004041:Dietary Fats / Q000008:administration & dosage; D004044:Dietary Proteins / Q000008:administration & dosage; D005247:Feeding Behavior / Q000187:drug effects / Q000502:physiology*; D005730:Ganglionic Blockers / Q000494:pharmacology; D006584:Hexamethonium Compounds / Q000494:pharmacology; D010179:Pancreas / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D051381:Rats; D011950:Receptors, Cholinergic / Q000187:drug effects / Q000502:physiology*
D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins; D005730:Ganglionic Blockers; D006584:Hexamethonium Compounds; D011950:Receptors, Cholinergic; D001535:Benactyzine; D001285:Atropine; C021628:benzohexonium