De novo complex chromosomal rearrangement in a woman with recurrent spontaneous abortion and one healthy daughter.
Although rare, complex chromosomal rearrangements have been reported in the literature. The result is multiple congenital malformations in the offspring and recurrent spontaneous abortion. Chromosome 7 is usually involved, but in our patient chromosome 18 was involved.
Timár
L
L
Department of Human Genetics and Teratology, National Institute of Hygiene, Budapest, Hungary.
Béres
J
J
Kosztolányi
G
G
Németh
I
I
D000026:Abortion, Habitual / Q000235:genetics*; D000328:Adult; D002871:Chromosome Banding; D002887:Chromosomes, Human, Pair 18; D002889:Chromosomes, Human, Pair 2; D002897:Chromosomes, Human, Pair 7; D005260:Female; D015321:Gene Rearrangement; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy; D014178:Translocation, Genetic; D014960:X Chromosome