A new model of systemic drug rescue based on permeability characteristics of the blood-brain barrier in intracerebral abscess-bearing rats.
Nazzaro
J M
JM
Division of Neurology, Oregon Health Sciences University, Portland.
Rosenbaum
L C
LC
Pagel
M A
MA
Neuwelt
E A
EA
D000818:Animals; D001812:Blood-Brain Barrier; D001921:Brain / Q000378:metabolism*; D001922:Brain Abscess / Q000378:metabolism*; D004927:Escherichia coli Infections / Q000378:metabolism; D005839:Gentamicins / Q000097:blood / Q000276:immunology / Q000493:pharmacokinetics*; D007136:Immunoglobulins / Q000378:metabolism; D007457:Iodine Radioisotopes; D010539:Permeability; D051381:Rats; D011919:Rats, Inbred Strains
D005839:Gentamicins; D007136:Immunoglobulins; D007457:Iodine Radioisotopes