title: Effect of bacterial pyrogen on three lizard species.
abstract: 1. Three lizard species (Callopistes maculatus, Gerrhosaurus major, and Varanus exanthematicus) were tested for their response to intraperitoneal injection of alcohol-killed Aeromonas sobria. 2. A paired experimental design, in which each animal received an injection of sterile saline and 1 x 10(10) A. sobria, was utilized. 3. C. maculatus demonstrated a statistically significant increase in mean selected body temperature (MSBT) after bacteria injection. 4. G. major and V. exanthematicus did not demonstrate a statistically significant increase in MSBT. 5. C. maculatus is the first lizard species outside of the family Iguanidae to exhibit a febrile response to bacterial pyrogen.
authors.affiliation: Department of Biology, California State University, Los Angeles 90032.
authors.forename: G M
authors.initials: GM
authors.lastname: Hallman
authors.forename: C E
authors.initials: CE
authors.lastname: Ortega
authors.forename: M C
authors.initials: MC
authors.lastname: Towner
authors.forename: A E
authors.initials: AE
authors.lastname: Muchlinski
mesh_terms: D000333:Aeromonas / Q000378:metabolism; D000818:Animals; D001831:Body Temperature / Q000187:drug effects; D008116:Lizards / Q000502:physiology*; D011749:Pyrogens / Q000494:pharmacology*; D013045:Species Specificity
chemical_list: D011749:Pyrogens