title: [Lichen planus: etiopathogenesis].
abstract: Lichen planus could result from a succession of immunological events: stimulation of Langerhans cells and keratinocytes by foreign antigen--production of interleukin 1 (IL 1)--activation, attraction and multiplication of helper T lymphocytes--production of interferon gamma--appearance of intercellular adhesion molecule-1 (ICAM 1) and HLA DR Antigen on keratinocytes membranes, allowing adhesion of T lymphocytes to keratinocytes and subsequent destruction of the latter.
authors.affiliation: Clinique Dermatologique, Hôpitaux Universitaires Saint-Pierre et Brugmann.
authors.forename: J
authors.initials: J
authors.lastname: André
authors.forename: M
authors.initials: M
authors.lastname: Laporte
authors.forename: P
authors.initials: P
authors.lastname: Delavault
mesh_terms: D015703:Antigens, CD / Q000276:immunology; D015815:Cell Adhesion Molecules / Q000276:immunology; D006684:HLA-DR Antigens / Q000276:immunology; D006801:Humans; D018799:Intercellular Adhesion Molecule-1; D007375:Interleukin-1 / Q000096:biosynthesis; D015603:Keratinocytes / Q000276:immunology; D007801:Langerhans Cells / Q000276:immunology; D008010:Lichen Planus / Q000276:immunology* / Q000503:physiopathology
chemical_list: D015703:Antigens, CD; D015815:Cell Adhesion Molecules; D006684:HLA-DR Antigens; D007375:Interleukin-1; D018799:Intercellular Adhesion Molecule-1