Variation in the protein coding region of the human p53 gene.
This report describes a restriction fragment length polymorphism for the enzyme BglII caused by a conserved C to T change at residue 21 of the human p53 gene. This RFLP could potentially be misinterpreted as a rearrangement or a point mutation if paired constitutional tissue is not simultaneously analyzed.
Ahuja
H G
HG
UCLA School of Medicine, Division of Hematology/Oncology 90024-1678.
Testa
M P
MP
Cline
M J
MJ
D000368:Aged; D006801:Humans; D011110:Polymorphism, Genetic; D012150:Polymorphism, Restriction Fragment Length; D016159:Tumor Suppressor Protein p53 / Q000235:genetics*
D016159:Tumor Suppressor Protein p53