title: Flow cytometric detection of tumor metastases during urologic surgery.
abstract: Flow cytometric studies were performed on peripheral blood obtained before, during, and subsequent to urologic surgery. The results suggest that 7 of 11 patients had a brief period during surgical manipulation when they had cells from the primary surgical site in the peripheral blood. Concentration of such cells was generally less than 10(2)/mL even during the intraoperative period. These findings suggest that perioperative tumor seeding is a real concern, and that flow cytometry can be used to study maneuvers to reduce its incidence.
authors.affiliation: Lee Streich Flow Cytometry Laboratory, Brooklyn, New York.
authors.forename: N J
authors.initials: NJ
authors.lastname: Nusbaum
authors.forename: R R
authors.initials: RR
authors.lastname: Kester
authors.forename: U M
authors.initials: UM
authors.lastname: Mooppan
authors.forename: H
authors.initials: H
authors.lastname: Kim
mesh_terms: D004273:DNA, Neoplasm / Q000032:analysis; D005434:Flow Cytometry; D006801:Humans; D007432:Intraoperative Period; D009362:Neoplasm Metastasis / Q000473:pathology / Q000517:prevention & control*; D009366:Neoplasm Seeding; D010865:Pilot Projects; D014571:Urologic Neoplasms / Q000601:surgery*
chemical_list: D004273:DNA, Neoplasm