15-Deoxyspergualin is a more potent and effective immunosuppressant than cyclosporine but does not effectively suppress lymphoproliferation in vivo.
Yuh
D D
DD
Department of Cardiovascular Surgery, Stanford University Medical Center, California 94301.
Morris
R E
RE
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D003524:Cyclosporins / Q000494:pharmacology / Q000627:therapeutic use*; D006084:Graft Rejection; D006085:Graft Survival; D006146:Guanidines / Q000494:pharmacology / Q000627:therapeutic use*; D016027:Heart Transplantation / Q000276:immunology* / Q000502:physiology; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008198:Lymph Nodes / Q000187:drug effects / Q000276:immunology; D008213:Lymphocyte Activation / Q000187:drug effects*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL
D003524:Cyclosporins; D006146:Guanidines; D007166:Immunosuppressive Agents; C037258:gusperimus