title: A case of maternity testing: exclusion by polymorphic VNTR markers of DNA.
abstract: The genetic markers of a Korean woman and her allegedly adopted child were compared to test her maternity. None of 21 conventional markers, including 8 red cell antigens, 6 red cell enzymes, and 7 serum proteins, excluded the maternity. These results indicate a maternal probability of 0.31 which was too low to conclude the true maternity. Human leukocyte antigen (HLA)-A, -B, -C and -DR haplotyping was also uninformative in this case. The maternity was consequently excluded by the observation of a difference in 2 of 5 variable number of tandem repeat (VNTR) markers.
authors.affiliation: Department of Legal Medicine, Shimane Medical University, Izuma, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Akane
authors.forename: H
authors.initials: H
authors.lastname: Nakajima
authors.forename: H
authors.initials: H
authors.lastname: Shiono
authors.forename: K
authors.initials: K
authors.lastname: Matsubara
authors.forename: M
authors.initials: M
authors.lastname: Yamada
authors.forename: Y
authors.initials: Y
authors.lastname: Nakagome
mesh_terms: D004247:DNA / Q000235:genetics*; D005260:Female; D005819:Genetic Markers; D006801:Humans; D009035:Mothers; D012150:Polymorphism, Restriction Fragment Length; D012091:Repetitive Sequences, Nucleic Acid
chemical_list: D005819:Genetic Markers; D004247:DNA