title: [Treatment of priapism with intracavernous injection of etilefrine hydrochloride].
abstract: A case of priapism following epidural anesthesia was reported. A 67 year old man received epidural anesthesia for the transurethral resection of a malignant bladder tumor. Epidural anesthesia which he had wanted to receive was given through the L3 to L4 intervertebral space with 18 ml of 2% lidocaine. The penile erection occurred while he was prepared and draped. Additional 8 ml of 1% lidocaine failed to overcome it and the operation cancelled. After this episode, he had anesthesia on 5 occasions in 2 years. General anesthesia was given 3 times without penile erection, but epidural block was tried on 2 occasions, which was followed by penile erection. For the penile erection, intracavernous injection of etilefrine hydrochloride was effective and surgical procedure could be done smoothly. The mechanism of priapism remained unclear but imbalance of the autonomic nervous system may be a involved. This case suggests that intracavernous injection of etilefrine hydrochloride is effective for treatment of penile erection during transurethral surgery.
authors.affiliation: Department of Anesthesiology, University of Hirosaki School of Medicine.
authors.forename: Y
authors.initials: Y
authors.lastname: Shimodate
authors.forename: N
authors.initials: N
authors.lastname: Dobashi
authors.forename: A
authors.initials: A
authors.lastname: Kudo
authors.forename: Y
authors.initials: Y
authors.lastname: Shinozaki
authors.forename: A
authors.initials: A
authors.lastname: Matsuki
mesh_terms: D000368:Aged; D000767:Anesthesia, Epidural / Q000009:adverse effects*; D005039:Etilefrine / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007267:Injections; D008297:Male; D010413:Penis; D011317:Priapism / Q000188:drug therapy* / Q000209:etiology
chemical_list: D005039:Etilefrine