[Alcohol withdrawal syndrome in the postoperative phase--therapy or prevention?].
In a prospective study 50 patients who reported regular ethanol consumption and who underwent neck dissection were evaluated by clinical examination and the Munich alcohol test (MALT). 31 patients were not classified as alcohol abusers and none of them developed withdrawal symptoms (WS) postoperatively. 19 patients were diagnosed as alcohol abusers; 9 of them (group 1) received symptomatic therapy with clomethiazol and haloperidol, 10 patients (group 2) received continuous ethanol infusions (2-4 g/h) postoperatively as prophylaxis for WS. 6 patients in group 1 developed WS; none of group 2 developed WS. Thus the period of intensive care therapy of group 2 was significantly shorter (3.0 versus 11.5 days). It was concluded that postoperative continuous ethanol infusions prevent the occurrence of WS and should be administered to severely alcoholic patients.
Heil
T
T
Klinik f. Anaesthesiologie und operative Intensivmedizin, Universitätsklinikum Steglitz der FU, Berlin.
Martens
D
D
Eyrich
K
K
D000430:Alcohol Withdrawal Delirium / Q000517:prevention & control*; D002719:Chlormethiazole / Q000008:administration & dosage*; D003422:Critical Care / Q000379:methods*; D004359:Drug Therapy, Combination; D006220:Haloperidol / Q000008:administration & dosage*; D006258:Head and Neck Neoplasms / Q000601:surgery*; D006801:Humans; D009460:Neurologic Examination; D011183:Postoperative Complications / Q000517:prevention & control*
D002719:Chlormethiazole; D006220:Haloperidol