[Pulsatile gonadotropin-releasing hormone substitution following excision of a craniopharyngioma with suprasellar invasion].
Craniopharyngeoma growing suprasellary attacks the medio-basal region of hypothalamus, that leads to the stopping of the production of gonadotropin releasing hormone. In connection with the case of a 15-year-old girl who had partial extirpation of craniopharyngeoma the authors write about the favourable endocrine effect of pulsatile gonadotropin releasing hormone treatment. Through giving gonadotropin releasing hormone every 90 minutes in 20 micrograms doses menstruation cycle and ovulation was performed. Beside surgical treatment hormonal substitution plays an important role in the treatment of additional endocrine symptoms.
Koloszár
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S
Szülészeti és Nögyógyászati Klinika, Szent-Györgi Albert Orvostudományi Egyetem, Szeged.
Bártfai
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G
Sas
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M
D000293:Adolescent; D003397:Craniopharyngioma / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage*; D006801:Humans; D008597:Menstrual Cycle / Q000187:drug effects; D009361:Neoplasm Invasiveness; D010062:Ovulation Induction; D010911:Pituitary Neoplasms / Q000188:drug therapy / Q000601:surgery*; D011673:Pulsatile Flow; D012658:Sella Turcica / Q000473:pathology
D007987:Gonadotropin-Releasing Hormone