title: Kawasaki-like syndrome after treatment with mesalazine.
abstract: We report a patient who developed a severe hypersensitivity reaction, including rash, lymph node enlargement, fever, hepatitis, and eosinophilia, after sulphasalazine therapy. Five years later, he developed a similar reaction after exposure to mesalazine, the salicylic compound of sulphasalazine. We conclude that patients with known severe systemic reaction to sulphasalazine therapy are also at risk for such a reaction when treated with a 5-ASA preparation.
authors.affiliation: University Hospital, Department of Infectious Diseases, Leiden, The Netherlands.
authors.forename: H
authors.initials: H
authors.lastname: Waanders
authors.forename: J
authors.initials: J
authors.lastname: Thompson
mesh_terms: D000328:Adult; D000636:Aminosalicylic Acids / Q000009:adverse effects*; D003424:Crohn Disease / Q000188:drug therapy; D006801:Humans; D008297:Male; D019804:Mesalamine; D009080:Mucocutaneous Lymph Node Syndrome / Q000139:chemically induced*; D013577:Syndrome
chemical_list: D000636:Aminosalicylic Acids; D019804:Mesalamine