Major histocompatibility complex restriction and cross-priming of H-Y antigen in rats.
Although female rats can be sensitized to H-Y-incompatible male skin isografts following exposure to MHC-incompatible male lymphoid cells, these cells are not as effective as MHC-compatible male cells. Evidence is presented that the effectiveness of the MHC-incompatible cells is a consequence of crosspriming and that such crosspriming only occurs if these cells are rejected.
Chen
H D
HD
Department of Dermatology, No. 1 Hospital of China Medical University, Shenyang.
Silvers
W K
WK
D000818:Animals; D005260:Female; D006182:H-Y Antigen / Q000276:immunology*; D007108:Immune Tolerance; D008285:Major Histocompatibility Complex; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D016038:Skin Transplantation; D014181:Transplantation Immunology
D006182:H-Y Antigen