title: Twenty-nail dystrophy treated with topical PUVA.
abstract: A case of twenty-nail dystrophy treated with topical PUVA is described. The patient, a 19-year-old woman, had a 4-year history of a nail dystrophy involving all finger- and toe-nails. The finger-nail changes were treated with topical PUVA, dose 0.7-1.4 J/cm2 x 3/week. After 7 months excellent improvement was seen, while the untreated toe-nails were unaffected. A maintenance dose of 0.7 J/cm2 x 3/week was necessary to prevent recurrence. We suggest that topical PUVA is worth trying for the treatment of twenty-nail dystrophy.
authors.affiliation: Department of Dermato-Venereology, University of Aarhus, Marselisborg Hospital, Denmark.
authors.forename: L
authors.initials: L
authors.lastname: Halkier-Sørensen
authors.forename: M
authors.initials: M
authors.lastname: Cramers
authors.forename: K
authors.initials: K
authors.lastname: Kragballe
mesh_terms: D000328:Adult; D005260:Female; D005385:Fingers; D006801:Humans; D008730:Methoxsalen; D009260:Nail Diseases / Q000188:drug therapy*; D011701:PUVA Therapy; D014034:Toes
chemical_list: D008730:Methoxsalen