Cardiac and splenic levels of norepinephrine and dopamine in copper deficient pigs and rats.
1. Copper deficiency decreased the concentration and content of norepinephrine in the hearts of pigs and rats. 2. Concentration, but not content, of norepinephrine was decreased in spleen of copper-deficient pigs, while splenic norepinephrine levels in rats were not altered by copper deficiency. 3. Cardiac and splenic concentrations and contents of dopamine were elevated in copper-deficient pigs and rats. 4. Tissue concentrations of catecholamines and the magnitude of change due to copper deficiency were greater in pigs than rats.
Schoenemann
H M
HM
Vitamin and Mineral Nutrition Laboratory, Beltsville Human Nutrition Research Center, U.S. Department of Agriculture, Agricultural Research Service, MD 20705.
Failla
M L
ML
Rosebrough
R W
RW
D000818:Animals; D001835:Body Weight; D003300:Copper / Q000008:administration & dosage / Q000172:deficiency* / Q000378:metabolism; D004032:Diet; D004298:Dopamine / Q000378:metabolism*; D005260:Female; D008099:Liver / Q000473:pathology; D008297:Male; D009206:Myocardium / Q000378:metabolism* / Q000473:pathology; D009638:Norepinephrine / Q000378:metabolism*; D009929:Organ Size; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000378:metabolism* / Q000473:pathology; D013552:Swine; D013950:Thymus Gland / Q000473:pathology
D003300:Copper; D004298:Dopamine; D009638:Norepinephrine