title: [Sipple's syndrome: a case report].
abstract: A 41-year-old woman was hospitalized for evaluation of diabetes mellitus and hypertension. The hormonal and radiological examinations revealed that she had pheochromocytoma of bilateral adrenal gland and medullary carcinoma of thyroid gland. Therefore, she was diagnosed as having Sipple's syndrome. She had no definite familial history, but her two sisters, already dead, had been strongly suspected of having had pheochromocytoma. First, bilateral adrenalectomy was performed and secondly, total thyroidectomy, excision of parathyroid and cervical lymph node dissection were performed. Histopathological diagnosis was pheochromocytoma of bilateral adrenal gland, medullary carcinoma of thyroid gland and chief cell hyperplasia of parathyroid gland. We report a case of Sipple's syndrome, which probably is the 88th case in Japan, with the review of the previous Japanese literature.
authors.affiliation: Department of Urology, Osaka University School of Medicine.
authors.forename: N
authors.initials: N
authors.lastname: Takaha
authors.forename: Y
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: S
authors.initials: S
authors.lastname: Takahara
authors.forename: A
authors.initials: A
authors.lastname: Okuyama
authors.forename: H
authors.initials: H
authors.lastname: Harada
authors.forename: B
authors.initials: B
authors.lastname: Sato
authors.forename: T
authors.initials: T
authors.lastname: Yoshida
authors.forename: S
authors.initials: S
authors.lastname: Takai
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000235:genetics / Q000473:pathology*; D000328:Adult; D002277:Carcinoma / Q000235:genetics / Q000473:pathology*; D005260:Female; D006801:Humans; D006965:Hyperplasia; D009377:Multiple Endocrine Neoplasia / Q000235:genetics / Q000473:pathology*; D010280:Parathyroid Glands / Q000473:pathology; D010673:Pheochromocytoma / Q000235:genetics / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000235:genetics / Q000473:pathology*