title: Relationship between tissue selectivity and lipophilicity for inhibitors of HMG-CoA reductase.
authors.affiliation: Department of Chemistry, Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, Ann Arbor, Michigan 48105.
authors.forename: B D
authors.initials: BD
authors.lastname: Roth
authors.forename: T M
authors.initials: TM
authors.lastname: Bocan
authors.forename: C J
authors.initials: CJ
authors.lastname: Blankley
authors.forename: A W
authors.initials: AW
authors.lastname: Chucholowski
authors.forename: P L
authors.initials: PL
authors.lastname: Creger
authors.forename: M W
authors.initials: MW
authors.lastname: Creswell
authors.forename: E
authors.initials: E
authors.lastname: Ferguson
authors.forename: R S
authors.initials: RS
authors.lastname: Newton
authors.forename: P
authors.initials: P
authors.lastname: O'Brien
authors.forename: J A
authors.initials: JA
authors.lastname: Picard
mesh_terms: D000818:Animals; D000924:Anticholesteremic Agents / Q000737:chemistry / Q000494:pharmacology*; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D007700:Kinetics; D008297:Male; D008861:Microsomes / Q000201:enzymology; D008862:Microsomes, Liver / Q000201:enzymology; D015394:Molecular Structure; D051381:Rats; D013154:Spleen / Q000201:enzymology; D013329:Structure-Activity Relationship; D013737:Testis / Q000201:enzymology
chemical_list: D000924:Anticholesteremic Agents; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors