title: Serous papillary adenocarcinoma of the tunica vaginalis of the testis with metastasis.
abstract: Testicular or paratesticular neoplasms that resemble the common epithelial type of ovarian tumor are quite rare. The authors report the case of a 29-year-old man with a metastatic serous papillary adenocarcinoma arising from the tunica vaginalis. To the authors' knowledge, this is the first reported case of a serous carcinoma of the tunica vaginalis behaving in a malignant fashion. The fact that clinically apparent metastatic disease occurred 4 years after initial presentation suggests that development of metastases is a late event. Unfortunately, the tumor has been refractory to therapy with chemotherapeutic agents with activity against ovarian malignancies.
authors.affiliation: Department of Medicine (Infectious Diseases), Crawford Long Hospital, Emory University, Atlanta, Georgia 30365.
authors.forename: H M
authors.initials: HM
authors.lastname: Blumberg
authors.forename: L E
authors.initials: LE
authors.lastname: Hendrix
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D003536:Cystadenocarcinoma / Q000473:pathology* / Q000556:secondary / Q000628:therapy; D006801:Humans; D008297:Male; D013736:Testicular Neoplasms / Q000473:pathology* / Q000628:therapy