[The participation of the hypophyseal-adrenal system in regulating alpha 2-adrenoreceptor reactivity. The effects of extreme exposures and alpha 2-adrenoblockaders].
The simulation of the hypo- and hyperactivity of the hypophysis-adrenocortical system induced considerable changes in the reactivity of alpha 2-adrenoceptors, as well as in the resistance of the organism to stressful influences. The findings support the assumption that the blockade of alpha 2-adrenoceptors is one of the key features in the adaptive mechanism of the glycocorticoid hormones action.
Shirinian
E A
EA
Martirosian
O M
OM
Arutiunian
S A
SA
Ataian
T K
TK
D000208:Acute Disease; D000315:Adrenalectomy; D000316:Adrenergic alpha-Agonists / Q000494:pharmacology; D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology*; D000818:Animals; D003655:Decerebrate State / Q000503:physiopathology; D006470:Hemorrhage / Q000503:physiopathology; D007016:Hypophysectomy; D000860:Hypoxia / Q000503:physiopathology; D002546:Ischemic Attack, Transient / Q000503:physiopathology; D010913:Pituitary-Adrenal System / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D011942:Receptors, Adrenergic, alpha / Q000187:drug effects / Q000502:physiology*; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000503:physiopathology*; D013563:Sympathectomy, Chemical
D000316:Adrenergic alpha-Agonists; D000317:Adrenergic alpha-Antagonists; D011942:Receptors, Adrenergic, alpha