8-(Dicyclopropylmethyl)-1,3-dipropylxanthine: a potent and selective adenosine A1 antagonist with renal protective and diuretic activities.
Shimada
J
J
Pharmaceutical Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Shizuoka-ken, Japan.
Suzuki
F
F
Nonaka
H
H
Karasawa
A
A
Mizumoto
H
H
Ohno
T
T
Kubo
K
K
Ishii
A
A
D000818:Animals; D004232:Diuretics / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D007668:Kidney / Q000187:drug effects / Q000502:physiology*; D007677:Kidney Function Tests; D007700:Kinetics; D008297:Male; D015394:Molecular Structure; D051381:Rats; D011919:Rats, Inbred Strains; D011983:Receptors, Purinergic / Q000187:drug effects* / Q000378:metabolism; D013329:Structure-Activity Relationship; D014970:Xanthines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
D004232:Diuretics; D007202:Indicators and Reagents; D011983:Receptors, Purinergic; D014970:Xanthines; C067197:8-(dicyclopropylmethyl)-1,3-dipropylxanthine