title: EDRF is an intracellular second messenger and autacoid to regulate cyclic GMP synthesis in many cells.
authors.affiliation: Abbott Laboratories, Abbott Park, IL 60064.
authors.forename: F
authors.initials: F
authors.lastname: Murad
authors.forename: K
authors.initials: K
authors.lastname: Ishii
authors.forename: U
authors.initials: U
authors.lastname: Förstermann
authors.forename: L
authors.initials: L
authors.lastname: Gorsky
authors.forename: J F
authors.initials: JF
authors.lastname: Kerwin
authors.forename: J
authors.initials: J
authors.lastname: Pollock
authors.forename: M
authors.initials: M
authors.lastname: Heller
mesh_terms: D000818:Animals; D001120:Arginine / Q000494:pharmacology; D002460:Cell Line; D002478:Cells, Cultured; D006152:Cyclic GMP / Q000096:biosynthesis* / Q000502:physiology; D004789:Enzyme Activation; D005347:Fibroblasts / Q000187:drug effects / Q000378:metabolism; D006162:Guanylate Cyclase / Q000145:classification / Q000378:metabolism*; D007527:Isoenzymes / Q000378:metabolism*; D008168:Lung / Q000196:embryology; D009569:Nitric Oxide / Q000494:pharmacology / Q000502:physiology*; D009928:Organ Specificity; D010084:Oxidation-Reduction; D051381:Rats; D015290:Second Messenger Systems
chemical_list: D007527:Isoenzymes; D009569:Nitric Oxide; D001120:Arginine; D006162:Guanylate Cyclase; D006152:Cyclic GMP