Inhibition of the metabolism of phosphatidylethanol and phosphatidic acid, and stimulation of insulin release, by propranolol in intact pancreatic islets.
Metz
S A
SA
Veterans Administration Medical Center, Denver, CO 80220.
Dunlop
M
M
D000818:Animals; D002478:Cells, Cultured; D004305:Dose-Response Relationship, Drug; D020404:Glycerophospholipids; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D010712:Phosphatidic Acids / Q000378:metabolism*; D010739:Phospholipase D / Q000037:antagonists & inhibitors*; D011433:Propranolol / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D020404:Glycerophospholipids; D007328:Insulin; D010712:Phosphatidic Acids; C051521:phosphatidylethanol; D011433:Propranolol; D010739:Phospholipase D