[Study of the APUD cells of the gastric mucosa].
The results of an histochemical and microscopic study of the APUD cells carried on gastric biopsies are reported. Endocrine cell hyperplasia, microscopically detected, was particularly evident in atrophic gastritis (type A chronic gastritis) and adenomas. The presence of the APUD cells confirmed by electronmicroscopy, which revealed granules of 200 NM with a central nucleus and a membrane-separating electron-lucent ring, gives a further contribution to the hypothesis of a possible association between endocrine cell hyperplasia and intestinal metaplasia.
Sampiero
G M
GM
Istituto di Chirurgia Generale, Università degli Studi di Messina.
Papalia
G
G
Caruso
R
R
Rando
L
L
Rizzo
A G
AG
Cuffari
B
B
Lo Forti
B
B
Di Pietro
N
N
Gorgone
S
S
Barbuscia
M
M
D001078:APUD Cells; D000236:Adenoma / Q000473:pathology; D000328:Adult; D000368:Aged; D001706:Biopsy; D002908:Chronic Disease; D004415:Dyspepsia / Q000473:pathology; D005753:Gastric Mucosa / Q000166:cytology*; D005757:Gastritis, Atrophic / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D008854:Microscopy, Electron; D008875:Middle Aged; D011127:Polyps / Q000473:pathology; D013274:Stomach Neoplasms / Q000473:pathology; D013276:Stomach Ulcer / Q000473:pathology