title: [Localization of RFLP probe Fr. 3-42 at 16p 13 band by in situ hybridization].
abstract: Recombinant plasmid clone Fr. 3-42(HGM9 no. D16S21) containing a human single-copy DNA segment of 1.9kb was hybridized to human chromosome preparations. Twenty-eight percent of hybridized metaphases exhibited silver grains at the terminal region of short arm of chromosome 16 (16p13). Close linkage between this probe and the human alpha 1 hemoglobin gene was demonstrated in another study.
authors.affiliation: Central Laboratory, First Affiliated Hospital Hunan Medical University, Changsha.
authors.forename: G H
authors.initials: GH
authors.lastname: Xiao
mesh_terms: D002885:Chromosomes, Human, Pair 16; D006801:Humans; D008297:Male; D009693:Nucleic Acid Hybridization; D012150:Polymorphism, Restriction Fragment Length