Familial ovarian cancer in Israeli Jewish women.
Among 310 women with ovarian cancer of epithelial origin, eight ovarian cancer-prone families were identified, accounting for 24 cases. Five first-degree relatives underwent prophylactic oophorectomy, and early ovarian carcinoma was diagnosed in one of them. Familial aggregation of ovarian cancer occurs in the Israeli Jewish population.
Menczer
J
J
Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel Hashomer, Israel.
Ben-Baruch
G
G
D005260:Female; D006801:Humans; D007557:Israel; D007585:Jews / Q000235:genetics*; D010051:Ovarian Neoplasms / Q000235:genetics* / Q000517:prevention & control; D010052:Ovariectomy; D010375:Pedigree