The reactions of pindolol, mepindolol, carazolol, and related model compounds with triethyl orthoformate: pathways and products of a new colour reaction.
The acid-catalysed electrophilic tandem substitutions of pindolol, mepindolol, and carazolol and some related model compounds with triethyl ortho formate give rise to new derivatives from the trishetaryl methane series. In some cases also further functionalized heterocycles were isolated. The structural aspects of the new trishetarylmethanes were discussed as C3-symmetric molecular propellers, respectively. The importance of the described reaction as colour reaction was mentioned.
Pindur
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U
Institut für Pharmazie im Fachbereich Chemie und Pharmazie der Universität, Mainz 1, F.R.G.
Witzel
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H
D000319:Adrenergic beta-Antagonists / Q000032:analysis*; D055598:Chemical Phenomena; D002621:Chemistry; D003116:Color; D007202:Indicators and Reagents; D010869:Pindolol / Q000031:analogs & derivatives / Q000032:analysis; D011412:Propanolamines / Q000032:analysis
D000319:Adrenergic beta-Antagonists; D007202:Indicators and Reagents; D011412:Propanolamines; C015340:mepindolol; C014382:carazolol; D010869:Pindolol