Implantation of tumor xenografts in nude mice: an improved methodology.
Xenografting of neoplasms is a common technique in cancer research. Implantation of non-uniform tumor tissue fragments often yields tumor nodules of irregular size and shape, which is disadvantageous. We therefore developed a device to standardize size and shape of such implants. This instrument is effective, inexpensive to fabricate, and simple to use.
Hudd
C A
CA
Department of Surgery, St. Louis University Medical Center, Missouri 63110-0250.
La Regina
M C
MC
Tolman
K C
KC
Johnson
F E
FE
D000818:Animals; D004867:Equipment Design; D008297:Male; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation / Q000379:methods*; D011786:Quality Control; D014183:Transplantation, Heterologous