title: Ablation of the atrioventricular junction with radiofrequency energy using a new electrode catheter.
abstract: Percutaneous catheter ablation using radiofrequency energy can be used to interrupt atrioventricular (AV) conduction in patients with supraventricular tachycardia refractory to drugs. Results of radiofrequency ablation of the AV junction using a custom-designed catheter with a large, 3-mm-long distal electrode, 2-mm interelectrode spacing, and a shaft with increased torsional rigidity were compared with those using a standard quadripolar electrode catheter (Bard EP). An electrocoagulator (Microvasive Bicap 4005) supplied unmodulated radiofrequency current at 550 kHz, which was applied between the distal electrode of the ablation catheter and a large skin electrode. With use of the modified catheter, 12 of 13 patients (92%) had persistent complete AV block induced with 7 +/- 5 applications of 18 +/- 6 W of radiofrequency power. In contrast, complete AV block was produced in only 9 of 18 (50%) historical control patients treated with the standard catheter, despite a similar number of applications (7 +/- 5) and power output (16 +/- 4 W). A rise in impedance, due to desiccation of tissue and coagulum formation, occurred earlier (28 +/- 18 vs 52 +/- 24 seconds, p less than 0.001) and more frequently (54 vs 40% of applications, p = 0.047) in patients treated with the standard catheter than in patients treated with the modified catheter. The use of a catheter designed to increase the surface area of electrode-tissue contact allows more radiofrequency energy to be delivered before a rise in impedance occurs and appears to increase the effectiveness of radiofrequency ablation of the AV junction.
authors.affiliation: Department of Medicine, University of California, San Francisco.
authors.forename: J J
authors.initials: JJ
authors.lastname: Langberg
authors.forename: M
authors.initials: M
authors.lastname: Chin
authors.forename: D J
authors.initials: DJ
authors.lastname: Schamp
authors.forename: M A
authors.initials: MA
authors.lastname: Lee
authors.forename: J
authors.initials: J
authors.lastname: Goldberger
authors.forename: D N
authors.initials: DN
authors.lastname: Pederson
authors.forename: M
authors.initials: M
authors.lastname: Oeff
authors.forename: M D
authors.initials: MD
authors.lastname: Lesh
authors.forename: J C
authors.initials: JC
authors.lastname: Griffin
authors.forename: M M
authors.initials: MM
authors.lastname: Scheinman
mesh_terms: D001283:Atrioventricular Node / Q000601:surgery*; D004562:Electrocardiography; D004564:Electrocoagulation / Q000295:instrumentation*; D004566:Electrodes; D004867:Equipment Design; D005260:Female; D006327:Heart Block / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D013617:Tachycardia, Supraventricular / Q000175:diagnosis / Q000601:surgery*