DNA: a model compound for solution studies of macromolecules.
Well-defined, monodisperse, homologous series of oligonucleotides and DNA restriction fragments may now be produced and used as models of rigid and semirigid rodlike molecules in solution. Information from optical experiments on these model systems aids in the formulation and testing of theories of macromolecular dynamics in both dilute and concentrated solution.
Pecora
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Stanford University, CA 94305-5080.
D001483:Base Sequence; D004247:DNA / Q000737:chemistry*; D008956:Models, Chemical; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides / Q000737:chemistry*; D010957:Plasmids; D011108:Polymers; D015183:Restriction Mapping
D009838:Oligodeoxyribonucleotides; D011108:Polymers; D004247:DNA