title: Acquired pendular nystagmus in toluene addiction.
abstract: We studied the ocular motor abnormalities in 4 patients chronically addicted to sniffing glue containing toluene. They showed acquired pendular nystagmus with horizontal and vertical components. One patient also showed saccadic oscillations. The pendular nystagmus may be a manifestation of a disturbance in brainstem-cerebellar connections secondary to the toxic effect of toluene on white matter.
authors.affiliation: Department of Neurology, Cleveland V.A. Medical Center, OH.
authors.forename: E F
authors.initials: EF
authors.lastname: Maas
authors.forename: J
authors.initials: J
authors.lastname: Ashe
authors.forename: P
authors.initials: P
authors.lastname: Spiegel
authors.forename: D S
authors.initials: DS
authors.lastname: Zee
authors.forename: R J
authors.initials: RJ
authors.lastname: Leigh
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D009759:Nystagmus, Pathologic / Q000209:etiology* / Q000503:physiopathology; D009801:Oculomotor Muscles / Q000503:physiopathology; D019966:Substance-Related Disorders / Q000150:complications*; D014050:Toluene / Q000506:poisoning
chemical_list: D014050:Toluene