title: [The changes in the enzymatic activity of glutathione metabolism in immobilization stress and their possible significance].
abstract: Immobilization of rats for 20 minutes and for 4 hours activates glutathione peroxidase in the heart, liver, and kidneys and glutathione transferase in the heart and liver, but inhibits gamma-glutamyl transferase in the liver and kidneys. Most of these changed values become normalized one hour after cessation of 4-hour stress. Propranolol completely prevents activation of glutathione peroxidase and glutathione transferase by stress. The changes in the activity of the glutathione metabolism enzymes are evidently of a protective character in relation to lipid peroxidation.
authors.forename: L S
authors.initials: LS
authors.lastname: Kolesnikov
authors.forename: N S
authors.initials: NS
authors.lastname: Mantorova
authors.forename: L A
authors.initials: LA
authors.lastname: Shapiro
authors.forename: V I
authors.initials: VI
authors.lastname: Kulinskiĭ
mesh_terms: D000818:Animals; D005260:Female; D005978:Glutathione / Q000378:metabolism*; D005979:Glutathione Peroxidase / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism; D007668:Kidney / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D009206:Myocardium / Q000201:enzymology; D051381:Rats; D011919:Rats, Inbred Strains; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000201:enzymology*; D013997:Time Factors; D005723:gamma-Glutamyltransferase / Q000378:metabolism
chemical_list: D005979:Glutathione Peroxidase; D005723:gamma-Glutamyltransferase; D005982:Glutathione Transferase; D005978:Glutathione