Peptidoglycan precursor from Fusobacterium nucleatum contains lanthionine.
Fusobacterium nucleatum was grown in the presence of [14C]UDP. By means of sequential precipitation and chromatographic separation of the cytoplasmic content, a peptidoglycan [14C]UDP pentapeptide containing lanthionine was isolated. This finding indicates that lanthionine is synthesized and incorporated as such during the assembly of the peptidoglycan.
Fredriksen
A
A
Department of Biochemistry, University of Bergen, Norway.
Vasstrand
E N
EN
Jensen
H B
HB
D000409:Alanine / Q000031:analogs & derivatives* / Q000378:metabolism; D002250:Carbon Radioisotopes; D002850:Chromatography, Gel; D002851:Chromatography, High Pressure Liquid; D005673:Fusobacterium / Q000378:metabolism*; D010457:Peptidoglycan / Q000096:biosynthesis* / Q000302:isolation & purification; D013440:Sulfides; D014530:Uridine Diphosphate / Q000378:metabolism*
D002250:Carbon Radioisotopes; D010457:Peptidoglycan; D013440:Sulfides; D014530:Uridine Diphosphate; C001520:lanthionine; D000409:Alanine