title: [Regional differences in drug use in relation to the causes].
abstract: The purpose of the study was in comparison of drug use in the treatment of coronary disease or hypertension in the random selected representative population sample of Warsaw and Tarnobrzeg province . In the study women and men aged 35 to 64 years were included according to POL-MONICA studies. Among 2646 subjects studied in Warsaw 23% used drugs whereas among 2722 subjects from the Tarnobrzeg province the drug users represented 12.1%. The most frequently used drugs in the treatment of coronary disease were nitrates, curantyl and beta-blockers. The drug use in subjects with coronary disease (DDD/1000 inhabitants/day) was 4.5-fold higher in Warsaw than in the Tarnobrzeg province . The most frequently drug used in treatment of hypertension in Warsaw were beta-blockers and diuretics, whereas in the Tarnobrzeg province among men diuretic and composed drug preparations; women in the last region used frequently composed drug preparations and smooth muscle relaxants. The relationship between the use of particular drug groups and the region was significant in women. The hypotensic drug use in Warsaw was twice as high as in the Tarnobrzeg voivodship despite similar frequency of hypertension in both regions.
authors.affiliation: Katedry Diagnostyki Biochemicznej i Kliniki Chorób Metabolicznych Akademii Medycznej w Krakowie.
authors.forename: B
authors.initials: B
authors.lastname: Idzior-Waluś
authors.forename: A
authors.initials: A
authors.lastname: Kuźmińska
authors.forename: J
authors.initials: J
authors.lastname: Sznajd
authors.forename: S
authors.initials: S
authors.lastname: Rywik
authors.forename: B
authors.initials: B
authors.lastname: Burkiet
authors.forename: G
authors.initials: G
authors.lastname: Broda
authors.forename: K
authors.initials: K
authors.lastname: Szuba
authors.forename: P
authors.initials: P
authors.lastname: Kurjata
authors.forename: A
authors.initials: A
authors.lastname: Pajak
authors.forename: M
authors.initials: M
authors.lastname: Polakowska
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage*; D000959:Antihypertensive Agents / Q000008:administration & dosage*; D003327:Coronary Disease / Q000188:drug therapy*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D009566:Nitrates / Q000008:administration & dosage*; D011044:Poland; D012424:Rural Population; D012737:Sex Factors; D014505:Urban Population
chemical_list: D000319:Adrenergic beta-Antagonists; D000959:Antihypertensive Agents; D009566:Nitrates