L-687,908, a potent hydroxyethylene-containing HIV protease inhibitor.
Vacca
J P
JP
Department of Medicinal Chemistry, Merck Sharp & Dohme Research Laboratories West Point, Pennsylvania 19486.
Guare
J P
JP
deSolms
S J
SJ
Sanders
W M
WM
Giuliani
E A
EA
Young
S D
SD
Darke
P L
PL
Zugay
J
J
Sigal
I S
IS
Schleif
W A
WA
D055598:Chemical Phenomena; D002621:Chemistry; D004151:Dipeptides / Q000737:chemistry*; D005030:Ethylenes / Q000737:chemistry*; D015683:Gene Products, gag / Q000378:metabolism; D016333:HIV Protease / Q000378:metabolism; D017320:HIV Protease Inhibitors; D015497:HIV-1 / Q000201:enzymology; D015394:Molecular Structure; D011498:Protein Precursors / Q000378:metabolism
D004151:Dipeptides; D005030:Ethylenes; D015683:Gene Products, gag; D017320:HIV Protease Inhibitors; D011498:Protein Precursors; C067836:L 687908; C067254:hydroxyethylene; D016333:HIV Protease