Sensitivity of urinary quantitative immunocytology with monoclonal antibody 486 P3/12 in 241 unselected patients with bladder carcinoma.
We investigated the sensitivity of quantitative immunocytology with our monoclonal antibody 486 P3/12 in 241 unselected patients with transitional cell carcinoma. Immunocytology yielded a sensitivity of 91.8%, 89.4% and 92.9% for grade 1, 2 and 3 tumors, respectively. Standard cytology was positive in 59.2%, 63.8% and 84.7%, respectively. Deoxyribonucleic acid flow cytometry, used in the first 69 patients, was positive in only 27.7%, 48.6% and 57.1%, respectively.
Klän
R
R
Department of Urology, Klinikum Steglitz, Freie Universitat Berlin, Germany.
Huland
E
E
Baisch
H
H
Huland
H
H
D000911:Antibodies, Monoclonal; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis*; D004273:DNA, Neoplasm / Q000032:analysis; D005434:Flow Cytometry; D006801:Humans; D012680:Sensitivity and Specificity; D001743:Urinary Bladder / Q000737:chemistry / Q000473:pathology*; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis*
D000911:Antibodies, Monoclonal; D004273:DNA, Neoplasm