title: Variations of nucleotide sequences and transcription of the SH gene among mumps virus strains.
abstract: We have compared nucleotide sequences of the SH genes as well as their flanking regions of six mumps virus strains and found a high amino acid diversity (up to 23%) of the putative SH proteins among these strains. It was found, in addition, that one of these strains (Enders strain) contained a point mutation in putative polyadenylation signal for the F gene mRNA (TTTAGAAAAAAA to TTTAGAAGAAAA). Northern blot analysis showed that the Enders strain was also unique in that neither monocistronic SH nor bicistronic SH-HN mRNA could be detected in the cells infected with this particular strain.
authors.affiliation: Department of Measles Virus, National Institute of Health, Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Takeuchi
authors.forename: K
authors.initials: K
authors.lastname: Tanabayashi
authors.forename: M
authors.initials: M
authors.lastname: Hishiyama
authors.forename: A
authors.initials: A
authors.lastname: Yamada
authors.forename: A
authors.initials: A
authors.lastname: Sugiura
mesh_terms: D000818:Animals; D001483:Base Sequence; D002642:Chick Embryo; D005814:Genes, Viral; D014644:Genetic Variation; D006367:HeLa Cells; D006801:Humans; D008969:Molecular Sequence Data; D009109:Mumps virus / Q000235:genetics*; D015345:Oligonucleotide Probes; D012333:RNA, Messenger / Q000235:genetics; D014158:Transcription, Genetic; D014709:Vero Cells
chemical_list: D015345:Oligonucleotide Probes; D012333:RNA, Messenger