title: Smooth pursuit eye movements in schizophrenia: influences of neuroleptic treatment and the question of specificity.
abstract: The authors investigated smooth pursuit eye movements (SPEMs) in 66 schizophrenic and 40 major affective patients and 39 healthy controls. The results showed significant differences of both patient groups as compared to the controls. Schizophrenics with neuroleptic treatment in the preceding 2 years were significantly more disturbed than the controls, the affective patients and the untreated schizophrenics. Acute neuroleptic medication and neuroleptic treatment of a duration of 4-6 weeks appear not to significantly influence the quality of SPEMs.
authors.affiliation: Psychiatric University Clinic, Vienna, Austria.
authors.forename: B
authors.initials: B
authors.lastname: Küfferle
authors.forename: A
authors.initials: A
authors.lastname: Friedmann
authors.forename: A
authors.initials: A
authors.lastname: Topitz
authors.forename: P
authors.initials: P
authors.lastname: Földes
authors.forename: P
authors.initials: P
authors.lastname: Anderer
authors.forename: M
authors.initials: M
authors.lastname: Kutzer
authors.forename: K
authors.initials: K
authors.lastname: Steinberger
mesh_terms: D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000175:diagnosis / Q000523:psychology; D003866:Depressive Disorder / Q000175:diagnosis / Q000523:psychology; D004585:Electrooculography / Q000295:instrumentation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008838:Microcomputers; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011698:Pursuit, Smooth / Q000187:drug effects*; D012559:Schizophrenia / Q000175:diagnosis / Q000188:drug therapy*; D012565:Schizophrenic Psychology; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation
chemical_list: D014150:Antipsychotic Agents