title: [Perioperative risk caused by alcohol and/or drug abuse. Which therapy?].
abstract: Alcohol and drug addicts usually suffer from polymorbidity. Withdrawal syndromes additionally endanger the success of surgical therapy. In opiate addicts withdrawal syndromes can and should be avoided by substitution of the drug or an analogon. In alcohol dependent patients the prophylaxis of withdrawal syndromes by i.v.-infusion of alcohol is not reliable. Therefore preference is given to the symptomatic therapy with combination of Benzodiazepin and Clonidin.
authors.affiliation: Abteilung für Anaesthesie und operative Intensivmedizin, St. Johannes-Hospital Dortmund.
authors.forename: R
authors.initials: R
authors.lastname: Purschke
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage; D000437:Alcoholism / Q000150:complications* / Q000534:rehabilitation*; D014151:Anti-Anxiety Agents / Q000008:administration & dosage; D001569:Benzodiazepines; D002719:Chlormethiazole / Q000008:administration & dosage; D003000:Clonidine / Q000008:administration & dosage; D000431:Ethanol / Q000008:administration & dosage; D006801:Humans; D007262:Infusions, Intravenous; D009460:Neurologic Examination; D011183:Postoperative Complications / Q000517:prevention & control*; D011619:Psychotropic Drugs / Q000009:adverse effects*; D013375:Substance Withdrawal Syndrome / Q000517:prevention & control*; D019966:Substance-Related Disorders / Q000150:complications* / Q000534:rehabilitation*
chemical_list: D000319:Adrenergic beta-Antagonists; D014151:Anti-Anxiety Agents; D011619:Psychotropic Drugs; D002719:Chlormethiazole; D001569:Benzodiazepines; D000431:Ethanol; D003000:Clonidine