Polyamines non-competitively inhibit [3H]3-PPP binding to sigma receptors.
Paul
I A
IA
Laboratory of Neuroscience, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892.
Kuypers
G
G
Youdim
M
M
Skolnick
P
P
D000313:Adrenal Medulla / Q000187:drug effects / Q000378:metabolism; D000818:Animals; D015317:Biogenic Polyamines / Q000494:pharmacology*; D001923:Brain Chemistry / Q000187:drug effects; D002417:Cattle; D015259:Dopamine Agents / Q000494:pharmacology*; D006168:Guinea Pigs; D066298:In Vitro Techniques; D007700:Kinetics; D010880:Piperidines / Q000378:metabolism*; D051381:Rats; D011957:Receptors, Opioid / Q000378:metabolism*; D017480:Receptors, sigma
D015317:Biogenic Polyamines; D015259:Dopamine Agents; D010880:Piperidines; D011957:Receptors, Opioid; D017480:Receptors, sigma; C026539:preclamol