title: Use of vaginal hysterectomy for the management of stage I endometrial cancer in the medically compromised patient.
abstract: Vaginal hysterectomy was performed on 31 patients with stage I endometrial cancer because of medical problems which placed them at high risk for morbidity and mortality from abdominal surgery. These risk factors included morbid obesity (87%), hypertension (58%), diabetes mellitus (35%), and cardiovascular diseases (26%). The perioperative morbidity was minimal, with only four patients (13%) experiencing complications requiring extended hospital stays and no deaths. Adjuvant radiotherapy was administered in 35% of patients with either deep myometrial invasion or unfavorable histology. The 3- and 5-year disease-free survival rates were 100 and 93%, respectively. The only cancer-related death occurred 4.5 years following surgery. Although the authors are not advocating vaginal hysterectomy as standard treatment of endometrial cancer, this approach provides an acceptable alternative to abdominal surgery in the medically compromised patient.
authors.affiliation: Division of Gynecologic Oncology, University of California, Irvine Medical Center, Orange 92668.
authors.forename: J D
authors.initials: JD
authors.lastname: Bloss
authors.forename: M L
authors.initials: ML
authors.lastname: Berman
authors.forename: L P
authors.initials: LP
authors.lastname: Bloss
authors.forename: R E
authors.initials: RE
authors.lastname: Buller
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000150:complications / Q000453:epidemiology; D003131:Combined Modality Therapy; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D006801:Humans; D007045:Hysterectomy, Vaginal; D008875:Middle Aged; D009767:Obesity, Morbid / Q000150:complications / Q000453:epidemiology; D012307:Risk Factors; D014594:Uterine Neoplasms / Q000150:complications / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*