Gastric emptying in gastroesophageal reflux and the therapeutic role of prokinetic agents.
The author discusses the role of prokinetic agents, such as bethanechol, metoclopramide, domperidone, and cisipride in the management of gastroesophageal reflux disease. These agents address the upper gastrointestinal motility disturbances that contribute to this disease and therefore have an important role in the acute and long-term medical management of reflux esophagitis.
McCallum
R W
RW
Division of Gastroenterology, University of Virginia School of Medicine, Charlottesville.
D018723:Bethanechol; D001626:Bethanechol Compounds / Q000627:therapeutic use*; D020117:Cisapride; D004294:Domperidone / Q000627:therapeutic use; D004943:Esophagogastric Junction / Q000187:drug effects*; D005746:Gastric Emptying / Q000187:drug effects; D005764:Gastroesophageal Reflux / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D008787:Metoclopramide / Q000627:therapeutic use*; D010880:Piperidines / Q000627:therapeutic use*; D012702:Serotonin Antagonists / Q000627:therapeutic use*
D001626:Bethanechol Compounds; D010880:Piperidines; D012702:Serotonin Antagonists; D018723:Bethanechol; D004294:Domperidone; D008787:Metoclopramide; D020117:Cisapride