[Etiological, determinant and systemic mechanisms of disorders of the central nervous system].
New concepts are related of the etiology and pathogenesis of a number of nervous disorders, resting on the theory of the generator, determinant and systemic mechanisms. It has been shown that after brain damage the development of the pathological process in this organ is put into effect by the endogenous mechanisms common to the altered nervous system itself. These mechanisms include origination of the generators of pathologically enhanced excitation, pathological determinants and pathological systems. Formation of the indicated pathological structural and functional formations comprises typical processes brought about, respectively, at the levels of interneuronal, systemic and ++intersystemic relations. These processes eventuate in formation of the pathological systems of the brain.
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D000222:Adaptation, Physiological; D001927:Brain Diseases / Q000209:etiology* / Q000517:prevention & control; D002540:Cerebral Cortex / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D009475:Neurons, Afferent / Q000502:physiology*; D018377:Neurotransmitter Agents / Q000502:physiology*; D012018:Reflex / Q000502:physiology
D018377:Neurotransmitter Agents