Frontal periventricular cysts on the first day of life. A one-year clinical follow-up and its significance.
During a 6-year period, the prospective interpretations of routine screening cranial ultrasound on 1453 premature infants indicated frontal periventricular cysts in 7 infants without other intracranial abnormalities during the first 24 hours after birth. The medical records of these 7 infants and their mothers and a developmental assessment at age 1 year were also reviewed. The cysts were predominantly single and unilateral and ranged in size from 2 to 11 mm. One infant had bilateral subependymal cysts as well as frontal periventricular cysts. All 7 infants before 1 year of age demonstrated mild neurological deficiencies. However, 6 of 7 demonstrated partial or complete resolution of their neurological impairment by the end of 1 year. One infant was lost to clinical follow-up. The presence of these frontal periventricular cysts in the first 24 hours after birth suggests an in-utero event, such as antepartum hemorrhagic infarction, as their etiology.
Sudakoff
G S
GS
Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, PA 19107-5244.
Mitchell
D G
DG
Stanley
C
C
Graziani
L J
LJ
D001927:Brain Diseases / Q000151:congenital / Q000000981:diagnostic imaging; D002552:Cerebral Ventricles / Q000000981:diagnostic imaging*; D003560:Cysts / Q000151:congenital / Q000000981:diagnostic imaging*; D005500:Follow-Up Studies; D005625:Frontal Lobe / Q000000981:diagnostic imaging*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature / Q000254:growth & development; D007235:Infant, Premature, Diseases / Q000000981:diagnostic imaging*; D011379:Prognosis; D011446:Prospective Studies; D012189:Retrospective Studies; D012307:Risk Factors; D014463:Ultrasonography