title: A study of H2 receptor antagonists in the treatment of chronic intractable pharyngitis.
abstract: In a controlled study of 75 patients suffering from chronic pharyngitis: 30 were treated with H2-receptor antagonist, 30 with H1-receptor antagonist, local decongestants and antiseptic gargles: and 15 treated with alum, salt or Dispirin gargles acted as controls. Best response was obtained with the first mode of treatment, raising the possibility of role of the H2-receptors in causing chronic pharyngitis. The difference was highly significant (P less than 0.001).
authors.affiliation: Department of E.N.T. and Head and Neck Surgery, Jinnah Postgraduate Medical Centre, Karachi.
authors.forename: S H
authors.initials: SH
authors.lastname: Zaidi
mesh_terms: D000328:Adult; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage; D002908:Chronic Disease; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications; D006635:Histamine H2 Antagonists / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008875:Middle Aged; D010612:Pharyngitis / Q000188:drug therapy* / Q000209:etiology; D011899:Ranitidine / Q000008:administration & dosage*; D013607:Tablets
chemical_list: D000891:Anti-Infective Agents, Local; D006635:Histamine H2 Antagonists; D013607:Tablets; D011899:Ranitidine