[Metastasis in lung and pleura].
The Topography, extent and histopathology of lung and pleural metastases in 132 surgical resections were investigated with regard to primary tumours. The emphasis was on postmortaly obtained angiographic results of the neovascularisation of metastases, mainly by vessels of the functional pulmonary circulation with diameters of 20-60 microns. Different phases of metastatic spread were considered such as invasion, embolisation and implantation. The pathologic-anatomic investigation of metastases is becoming more and more important for morphological quantification of tumour regression following cytostatic therapy and for clarifying unknown primary tumours by the immunohistochemical examination of lung metastases.
Müller
K M
KM
Berufsgenossenschaftliche Krankenanstalten Bergmannsheil-Universitätsklinik, Institut für Pathologie, Bochum.
Respondek
M
M
Hesse
H
H
D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology* / Q000556:secondary*; D009361:Neoplasm Invasiveness; D009360:Neoplastic Cells, Circulating; D010994:Pleura / Q000473:pathology; D010997:Pleural Neoplasms / Q000473:pathology* / Q000556:secondary*