title: Staphylococcus aureus exit-site and tunnel infection in CAPD.
abstract: Fifty-six S. aureus episodes of catheter exit-site tunnel infections were diagnosed in 40 out of 163 patients treated by CAPD for 30 +/- 22 months, with standard double-cuff Tenckhoff catheters. The rate of infection was 1 episode every 29 patient/months. Local care and antibiotic therapy were effective in 52% of the cases. Whereas in 29 episodes in which the medical therapy failed to eradicate the infection the entire area of granulation tissue and cellulitis was excised then the outer dacron cuff was shaved from the silicone catheter. With this treatment 13 episodes (48%) were cured while, in the remaining 14 patients the catheters were removed because of peritonitis in 10; and for failure to eradicate the infection in 4.
authors.affiliation: Divisione di Nefrologia e Dialisi, Ospedale Maggiore di Milano, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Scalamogna
authors.forename: C
authors.initials: C
authors.lastname: Castelnovo
authors.forename: A
authors.initials: A
authors.lastname: De Vecchi
authors.forename: L
authors.initials: L
authors.lastname: Guerra
authors.forename: C
authors.initials: C
authors.lastname: Ponticelli
mesh_terms: D002408:Catheters, Indwelling; D003646:Debridement; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects*; D011206:Povidone-Iodine / Q000008:administration & dosage; D012293:Rifampin / Q000008:administration & dosage / Q000627:therapeutic use; D013207:Staphylococcal Skin Infections / Q000453:epidemiology* / Q000628:therapy; D014640:Vancomycin / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D014640:Vancomycin; D011206:Povidone-Iodine; D012293:Rifampin