Blood stage-induced Plasmodium brasilianum infection in the squirrel monkey induces antibodies which react with the circumsporozoite protein.
A blood stage-induced P. brasilianum infection in a naive squirrel monkey induced antibodies which reacted with the circumsporozoite protein of the parasite. Titers increased with duration of infection and persisted for 3 months after cure. In an immunoblot, these antibodies detected two polypeptides with molecular weights identical to those of the circumsporozoite protein and its precursor.
Cochrane
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Department of Medical and Molecular Parasitology, New York University School of Medicine, New York 10016.
Maracic
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M
D000818:Animals; D000913:Antibodies, Protozoan / Q000276:immunology*; D000953:Antigens, Protozoan / Q000276:immunology*; D015153:Blotting, Western; D004797:Enzyme-Linked Immunosorbent Assay; D007114:Immunization; D008288:Malaria / Q000276:immunology*; D008970:Molecular Weight; D009842:Oligopeptides / Q000276:immunology; D015800:Protozoan Proteins; D012453:Saimiri
D000913:Antibodies, Protozoan; D000953:Antigens, Protozoan; D009842:Oligopeptides; D015800:Protozoan Proteins; C041595:circumsporozoite protein, Protozoan