[Phospholipid methylation and the synaptosomal uptake of mediator amino acids].
The decrease in neurotransmitter amino acid uptake was observed in rat brain synaptosomes incubated with S-adenosyl-L-methyl-methionine. The inhibitory effect of neurotransmitter as a consequence of methylation of synaptic membrane is more pronounced in stimulatory transmitter amino acids. The effect of phospholipids on amino acid uptake in rat brain synaptosomes decreases with age.
Vartanian
A A
AA
Aprikian
G V
GV
Vaniushin
B F
BF
D000375:Aging / Q000378:metabolism; D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000378:metabolism; D007425:Intracellular Membranes / Q000378:metabolism; D008297:Male; D008745:Methylation; D009411:Nerve Endings / Q000378:metabolism; D018377:Neurotransmitter Agents / Q000378:metabolism*; D010743:Phospholipids / Q000378:metabolism*; D051381:Rats; D013574:Synaptosomes / Q000378:metabolism*
D000596:Amino Acids; D018377:Neurotransmitter Agents; D010743:Phospholipids