title: [Diagnosis and therapy of hyperinsulinism].
abstract: The diagnosis of hyperinsulinism in our 47 patients could be confirmed by clinical signs, blood sugar, insulin and C-peptide estimation. The preoperative localisation of the insulinoma was reached by angiography in 60%, by CT in 50% and by sonography in 10%. Intraoperative tumor localisation by measurement of incorporated P32 was effective in 70%. In 37 patients we enucleated one or more adenomas. In 5 children with Nesidioblastosis the left sided pancreas resection was performed. 5 patients with islet cell carcinoma were treated by duodenopancreatectomy and Streptozotocin. The longest survival time was 6 years.
authors.affiliation: Chirurgische Klinik (Charité), Humboldt-Universität, Berlin.
authors.forename: H
authors.initials: H
authors.lastname: Lippert
authors.forename: H
authors.initials: H
authors.lastname: Wolff
authors.forename: F
authors.initials: F
authors.lastname: Kühn
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003952:Diagnostic Imaging; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006946:Hyperinsulinism / Q000175:diagnosis* / Q000601:surgery*; D007223:Infant; D007340:Insulinoma / Q000175:diagnosis* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy; D010186:Pancreatic Function Tests