Structure and expression of canary myc family genes.
We found that the canary N-myc gene is highly related to mammalian N-myc genes in both the protein-coding region and the long 3' untranslated region. Examined coding regions of the canary c-myc gene were also highly related to their mammalian counterparts, but in contrast to N-myc, the canary and mammalian c-myc genes were quite divergent in their 3' untranslated regions. We readily detected N-myc and c-myc expression in the adult canary brain and found N-myc expression both at sites of proliferating neuronal precursors and in mature neurons.
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Howard Hughes Medical Institute, College of Physicians and Surgeons, Columbia University, New York, New York 10032.
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D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002171:Canaries / Q000235:genetics*; D002645:Chickens; D006801:Humans; D051379:Mice; D008969:Molecular Sequence Data; D016271:Proto-Oncogene Proteins c-myc / Q000235:genetics*; D011519:Proto-Oncogenes
D016271:Proto-Oncogene Proteins c-myc