Effects of parasympathectomy on protein composition of sympathetically evoked parotid saliva in rats.
1. Male Wistar rats were given unilateral postganglionic parasympathectomies by sectioning the auriculo-temporal nerve. 2. Analyses of the protein compositions of sympathetically induced saliva from both glands 1 week later revealed changes in the proportions of different secretory proteins, in particular amylase and basic proline-rich proteins were decreased. 3. These results suggest that parasympathetic impulses are required for the normal synthesis of amylase by parotid parenchyma in rats. Basic proline-rich proteins, known to require a sympathetic drive for normal synthesis, appear to require a parasympathetic input as well.
Proctor
G B
GB
Department Oral Pathology, King's College School of Medicine & Dentistry, Rayne Institute, London, U.K.
Asking
B
B
Garrett
J R
JR
D000818:Animals; D002853:Chromatography, Liquid; D003714:Denervation; D004558:Electric Stimulation; D004591:Electrophoresis, Polyacrylamide Gel; D008297:Male; D010275:Parasympathetic Nervous System / Q000502:physiology*; D010306:Parotid Gland / Q000294:innervation / Q000378:metabolism* / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D012463:Saliva / Q000737:chemistry*; D012471:Salivary Proteins and Peptides / Q000737:chemistry*; D013564:Sympathetic Nervous System / Q000502:physiology*
D012471:Salivary Proteins and Peptides