Mutagenicity, carcinogenicity and toxicity of beta-naphthoflavone, a potent inducer of P448.
McKillop
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Safety of Medicines Department, ICI Pharmaceuticals, Macclesfield, Cheshire, United Kingdom.
Case
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DE
D000818:Animals; D001571:Benzoflavones / Q000494:pharmacology* / Q000633:toxicity; D015197:Carcinogenicity Tests; D019388:Cytochrome P-450 CYP1A2; D003580:Cytochromes / Q000096:biosynthesis*; D004790:Enzyme Induction; D006801:Humans; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology; D009152:Mutagenicity Tests; D019324:beta-Naphthoflavone
D001571:Benzoflavones; D003580:Cytochromes; D019324:beta-Naphthoflavone; C017170:Cyp1a2 protein, rat; D019388:Cytochrome P-450 CYP1A2