title: The human Y chromosome shows a low level of DNA polymorphism.
abstract: Six new Y-specific probes have been isolated and are reported. Along with another six already described they have been used in a systemic search for male specific RFLPs. An overall number of 46515 nucleotides have been screened with 12 enzymes and no polymorphic pattern observed. Our data reveal a greatly reduced level of polymorphism compared with other chromosomes.
authors.affiliation: Dipartimento di Biologia, Università Tor Vergata, Rome, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Malaspina
authors.forename: F
authors.initials: F
authors.lastname: Persichetti
authors.forename: A
authors.initials: A
authors.lastname: Novelletto
authors.forename: C
authors.initials: C
authors.lastname: Iodice
authors.forename: L
authors.initials: L
authors.lastname: Terrenato
authors.forename: J
authors.initials: J
authors.lastname: Wolfe
authors.forename: M
authors.initials: M
authors.lastname: Ferraro
authors.forename: G
authors.initials: G
authors.lastname: Prantera
mesh_terms: D000818:Animals; D002871:Chromosome Banding; D015342:DNA Probes; D005260:Female; D006801:Humans; D006822:Hybrid Cells; D008297:Male; D051379:Mice; D012150:Polymorphism, Restriction Fragment Length; D015183:Restriction Mapping; D014998:Y Chromosome
chemical_list: D015342:DNA Probes