title: 8-(Dicyclopropylmethyl)-1,3-dipropylxanthine: a potent and selective adenosine A1 antagonist with renal protective and diuretic activities.
authors.affiliation: Pharmaceutical Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Shizuoka-ken, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Shimada
authors.forename: F
authors.initials: F
authors.lastname: Suzuki
authors.forename: H
authors.initials: H
authors.lastname: Nonaka
authors.forename: A
authors.initials: A
authors.lastname: Karasawa
authors.forename: H
authors.initials: H
authors.lastname: Mizumoto
authors.forename: T
authors.initials: T
authors.lastname: Ohno
authors.forename: K
authors.initials: K
authors.lastname: Kubo
authors.forename: A
authors.initials: A
authors.lastname: Ishii
mesh_terms: D000818:Animals; D004232:Diuretics / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D007668:Kidney / Q000187:drug effects / Q000502:physiology*; D007677:Kidney Function Tests; D007700:Kinetics; D008297:Male; D015394:Molecular Structure; D051381:Rats; D011919:Rats, Inbred Strains; D011983:Receptors, Purinergic / Q000187:drug effects* / Q000378:metabolism; D013329:Structure-Activity Relationship; D014970:Xanthines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
chemical_list: D004232:Diuretics; D007202:Indicators and Reagents; D011983:Receptors, Purinergic; D014970:Xanthines; C067197:8-(dicyclopropylmethyl)-1,3-dipropylxanthine