Characteristics of bronchodilating activity of formoterol.
Formoterol possesses a chemical structure characterized by an NH group attached to the benzene ring and an important side chain. This characteristic may explain its long-lasting effects observed in animal and humans. Formoterol is as active as salbutamol in terms of maximum improvement of FEV1 and its bronchodilating effect is observed at all levels of the bronchial tree.
Clauzel
A M
AM
Hôpital l'Aiguelonge, Montpellier, France.
D000280:Administration, Inhalation; D000318:Adrenergic beta-Agonists; D000403:Airway Resistance / Q000187:drug effects; D001249:Asthma / Q000188:drug therapy*; D001993:Bronchodilator Agents; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D004983:Ethanolamines / Q000008:administration & dosage*; D005260:Female; D005541:Forced Expiratory Volume / Q000187:drug effects; D000068759:Formoterol Fumarate; D006801:Humans; D008297:Male; D016032:Randomized Controlled Trials as Topic
D000318:Adrenergic beta-Agonists; D001993:Bronchodilator Agents; D004983:Ethanolamines; D000068759:Formoterol Fumarate