Influence of isoniazid, phenobarbital, phenytoin, pregnenolone 16-alpha carbonitrile, and beta-naphthoflavone on halothane metabolism and hepatotoxicity.
Jenner
M A
MA
Department of Anaesthesia and Intensive Care, Flinders Medical Centre, Bedford Park, South Australia.
Plummer
J L
JL
Cousins
M J
MJ
D000818:Animals; D001571:Benzoflavones / Q000494:pharmacology; D056486:Chemical and Drug Induced Liver Injury / Q000378:metabolism*; D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis; D004790:Enzyme Induction / Q000187:drug effects; D006221:Halothane / Q000378:metabolism* / Q000633:toxicity; D000860:Hypoxia / Q000503:physiopathology; D007538:Isoniazid / Q000494:pharmacology; D010084:Oxidation-Reduction; D010634:Phenobarbital / Q000494:pharmacology; D010672:Phenytoin / Q000494:pharmacology; D011285:Pregnenolone Carbonitrile / Q000494:pharmacology; D051381:Rats; D019324:beta-Naphthoflavone
D001571:Benzoflavones; D011285:Pregnenolone Carbonitrile; D019324:beta-Naphthoflavone; D010672:Phenytoin; D003577:Cytochrome P-450 Enzyme System; D006221:Halothane; D007538:Isoniazid; D010634:Phenobarbital