title: Interventional neurovascular treatment of a giant intracranial aneurysm using platinum microcoils.
abstract: A 70-year-old woman presented with symptoms of progressive cerebellar dysfunction due to mass effect from a giant, expanding, posterior fossa aneurysm arising from the distal vertebral artery. The aneurysm contained thrombus and had a broad-based neck. From a transfemoral approach, with the patient under local anesthesia, a 2.2 French microcatheter was guided through the vertebral artery and placed directly into the aneurysm. Six 5 x 15-mm platinum microcoils were deposited into the residual lumen of the aneurysm, resulting in complete thrombosis with obliteration of the aneurysm and preservation of the parent artery. Endovascular coil embolization therapy by interventional neurovascular techniques may provide a therapeutic alternative in the management of surgically difficult symptomatic intracranial aneurysms.
authors.affiliation: Department of Radiology, University of California San Francisco Medical Center 94143-0628.
authors.forename: R T
authors.initials: RT
authors.lastname: Higashida
authors.forename: V V
authors.initials: VV
authors.lastname: Halbach
authors.forename: C F
authors.initials: CF
authors.lastname: Dowd
authors.forename: S L
authors.initials: SL
authors.lastname: Barnwell
authors.forename: G B
authors.initials: GB
authors.lastname: Hieshima
mesh_terms: D000368:Aged; D003388:Cranial Fossa, Posterior / Q000473:pathology; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D010984:Platinum; D013525:Surgical Instruments
chemical_list: D010984:Platinum