[Is there a reliable adjuvant (intraoperative) chemotherapy of colorectal cancer?].
On the basis of a considerable number of carefully designed, representative, and controlled studies adjuvant chemotherapy was considered uneffective for patients with colorectal cancer. In the light of the very recently published results obtained with the combination of 5-fluorouracil plus levamisole this option must now be reconsidered. However, the statement of the NCI that all patients with Dukes'C cancer should be offered this combination appears premature.
Hossfeld
D K
DK
Abteilung Onkonologie-Hämatologie, Universitätskrankenhauses Hamburg-Eppendorf.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D003131:Combined Modality Therapy; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007978:Levamisole / Q000008:administration & dosage; D009367:Neoplasm Staging
D007978:Levamisole; D005472:Fluorouracil