Buspirone augmentation of fluoxetine in patients with obsessive compulsive disorder.
Twenty patients with obsessive compulsive disorder were treated openly with fluoxetine for 20 weeks. In 10 of the patients, addition of buspirone during the last 8 weeks improved clinical response. The role of augmenting strategies is discussed.
Jenike
M A
MA
Harvard Medical School, Boston, Mass.
Baer
L
L
Buttolph
L
L
D002065:Buspirone / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005473:Fluoxetine / Q000627:therapeutic use*; D006801:Humans; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy* / Q000523:psychology; D010865:Pilot Projects; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales
D005473:Fluoxetine; D002065:Buspirone