[The effect of the application technic on the formal success of large-field radiotherapies].
198 patients suffering from Hodgkin's disease or non-Hodgkin's lymphomas were irradiated with large-field techniques from 1979 to 1988. 129 of these were treated with common block techniques whereas the field-integrated dose modification (FIDM) was applied to 69 patients. Retrospective analysis shows that FIDM decreases acute toxicity. This was also evident in those patients who were irradiated by accelerated hyperfractionation. Although single doses were higher in patients treated with FIDM treatment had to be interrupted or abandoned less often than in those treated with conventional block techniques. Even high-risk patients could be irradiated more consequently.
Baron
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Abteilung Radiologie, Christian-Albrechts-Universität zu Kiel.
Brix
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D000368:Aged; D000369:Aged, 80 and over; D001853:Bone Marrow / Q000528:radiation effects; D005260:Female; D006689:Hodgkin Disease / Q000150:complications / Q000532:radiotherapy; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D011878:Radiotherapy / Q000009:adverse effects / Q000379:methods* / Q000706:statistics & numerical data; D011879:Radiotherapy Dosage; D012189:Retrospective Studies; D013997:Time Factors