Inhalation delivery of asthma drugs.
In the immediate future, metered-dose inhalers (MDIs) with spacers remain the aerosol application of choice for topical steroids, mainly to reduce side effects. For beta 2-agonist, anticholinergics and prophylactic drugs, MDI (with or without demand valve), dry powder inhalers (multidose inhalers), ultrasonic or jet aerosol generators (with or without mechanical breathing assistance [IPPB]) are chosen according to the preference or the ability of the patients to perform the necessary breathing maneuvers as well as the availability of different products in different countries.
Matthys
H
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Division of Pneumology, Medical Department, University of Freiburg, Federal Republic of Germany.
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000318:Adrenergic beta-Agonists / Q000008:administration & dosage; D000336:Aerosols; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage; D001249:Asthma / Q000188:drug therapy*; D004205:Cromolyn Sodium / Q000008:administration & dosage; D004305:Dose-Response Relationship, Drug; D006801:Humans; D009330:Nebulizers and Vaporizers; D017835:Nedocromil; D010276:Parasympatholytics / Q000008:administration & dosage; D011208:Powders; D015363:Quinolones / Q000008:administration & dosage
D000305:Adrenal Cortex Hormones; D000318:Adrenergic beta-Agonists; D000336:Aerosols; D000894:Anti-Inflammatory Agents, Non-Steroidal; D010276:Parasympatholytics; D011208:Powders; D015363:Quinolones; D017835:Nedocromil; D004205:Cromolyn Sodium