title: Role of RpoH, a heat shock regulator protein, in Escherichia coli carbon starvation protein synthesis and survival.
abstract: Escherichia coli starvation proteins include several heat shock proteins whose induction by heat is controlled by the minor sigma factor, sigma 32. The level of sigma 32 increased in wild-type E. coli upon starvation, and three sigma 32-controlled heat shock proteins (DnaK, GroEL, and HtpG) were not induced during starvation in an isogenic delta rpoH strain, which is unable to synthesize sigma 32. Thus, sigma 32 plays a role in the induction of these proteins during both heat shock and starvation. The delta rpoH strain was more sensitive to starvation but could develop starvation-mediated cross protection against heat and oxidation.
authors.affiliation: Department of Microbiology and Immunology, Stanford University School of Medicine, California 94305-5402.
authors.forename: D E
authors.initials: DE
authors.lastname: Jenkins
authors.forename: E A
authors.initials: EA
authors.lastname: Auger
authors.forename: A
authors.initials: A
authors.lastname: Matin
mesh_terms: D001426:Bacterial Proteins / Q000096:biosynthesis / Q000235:genetics; D002244:Carbon / Q000378:metabolism; D002872:Chromosome Deletion; D015180:Electrophoresis, Gel, Two-Dimensional; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism*; D015964:Gene Expression Regulation, Bacterial; D005947:Glucose / Q000378:metabolism; D006360:Heat-Shock Proteins / Q000235:genetics* / Q000378:metabolism; D006358:Hot Temperature; D012808:Sigma Factor / Q000502:physiology*; D013217:Starvation
chemical_list: D001426:Bacterial Proteins; D006360:Heat-Shock Proteins; D012808:Sigma Factor; D002244:Carbon; D005947:Glucose