Acquired pendular nystagmus in toluene addiction.
We studied the ocular motor abnormalities in 4 patients chronically addicted to sniffing glue containing toluene. They showed acquired pendular nystagmus with horizontal and vertical components. One patient also showed saccadic oscillations. The pendular nystagmus may be a manifestation of a disturbance in brainstem-cerebellar connections secondary to the toxic effect of toluene on white matter.
Maas
E F
EF
Department of Neurology, Cleveland V.A. Medical Center, OH.
Ashe
J
J
Spiegel
P
P
Zee
D S
DS
Leigh
R J
RJ
D000328:Adult; D006801:Humans; D008297:Male; D009759:Nystagmus, Pathologic / Q000209:etiology* / Q000503:physiopathology; D009801:Oculomotor Muscles / Q000503:physiopathology; D019966:Substance-Related Disorders / Q000150:complications*; D014050:Toluene / Q000506:poisoning
D014050:Toluene