(R)-4-oxo-5-phosphononorvaline: a new competitive glutamate antagonist at the NMDA receptor complex.
Whitten
J P
JP
Merrell Dow Research Institute, Cincinnati Center, Ohio 45215.
Baron
B M
BM
Muench
D
D
Miller
F
F
White
H S
HS
McDonald
I A
IA
D000818:Animals; D001667:Binding, Competitive; D002531:Cerebellum / Q000187:drug effects / Q000378:metabolism; D006152:Cyclic GMP / Q000378:metabolism; D018691:Excitatory Amino Acid Antagonists; D005971:Glutamates / Q000378:metabolism; D018698:Glutamic Acid; D007696:Kindling, Neurologic / Q000187:drug effects; D051379:Mice; D008811:Mice, Inbred DBA; D016202:N-Methylaspartate / Q000037:antagonists & inhibitors / Q000378:metabolism* / Q000494:pharmacology; D051381:Rats; D016194:Receptors, N-Methyl-D-Aspartate / Q000037:antagonists & inhibitors* / Q000378:metabolism; D014633:Valine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism
D018691:Excitatory Amino Acid Antagonists; D005971:Glutamates; D016194:Receptors, N-Methyl-D-Aspartate; C066280:4-oxo-5-phosphononorvaline; D018698:Glutamic Acid; D016202:N-Methylaspartate; D006152:Cyclic GMP; D014633:Valine