title: Etiology of prosthetic anastomotic false aneurysms: pathologic and structural evaluation in 26 cases.
abstract: To determine the etiology of anastomotic false aneurysms (AFAs), 26 textile graft specimens, removed because of AFA, were studied morphologically, histologically and by scanning electron microscopy. No cases of suture-related failures leading to AFA were found. Nine cases of frayed grafts were documented but were not the cause of AFA formation. In three cases, chemical degradation of the fibres, which may have been secondary to lipid infiltration, may have contributed to AFA formation. There were no cases of overt clinical infection, but the presence of bacteria was documented by scanning electron microscopy in 20 cases. The role of bacteria is not well defined, but they may be a factor in host arterial-wall degeneration as a cause for AFA formation.
authors.affiliation: Biomaterials Institute, St-François d'Assise Hospital, Laval University, Quebec.
authors.forename: A R
authors.initials: AR
authors.lastname: Downs
authors.forename: R
authors.initials: R
authors.lastname: Guzman
authors.forename: M
authors.initials: M
authors.lastname: Formichi
authors.forename: R
authors.initials: R
authors.lastname: Courbier
authors.forename: J M
authors.initials: JM
authors.lastname: Jausseran
authors.forename: A
authors.initials: A
authors.lastname: Branchereau
authors.forename: C
authors.initials: C
authors.lastname: Juhan
authors.forename: N
authors.initials: N
authors.lastname: Chakfe
authors.forename: M
authors.initials: M
authors.lastname: King
authors.forename: R
authors.initials: R
authors.lastname: Guidoin
mesh_terms: D000328:Adult; D000368:Aged; D000714:Anastomosis, Surgical / Q000009:adverse effects; D001012:Aorta, Abdominal; D001014:Aortic Aneurysm / Q000209:etiology*; D001157:Arterial Occlusive Diseases / Q000209:etiology; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D011126:Polypropylenes; D011475:Prosthesis Failure; D012086:Reoperation; D013537:Sutures
chemical_list: D011126:Polypropylenes