The human Y chromosome shows a low level of DNA polymorphism.
Six new Y-specific probes have been isolated and are reported. Along with another six already described they have been used in a systemic search for male specific RFLPs. An overall number of 46515 nucleotides have been screened with 12 enzymes and no polymorphic pattern observed. Our data reveal a greatly reduced level of polymorphism compared with other chromosomes.
Malaspina
P
P
Dipartimento di Biologia, Università Tor Vergata, Rome, Italy.
Persichetti
F
F
Novelletto
A
A
Iodice
C
C
Terrenato
L
L
Wolfe
J
J
Ferraro
M
M
Prantera
G
G
D000818:Animals; D002871:Chromosome Banding; D015342:DNA Probes; D005260:Female; D006801:Humans; D006822:Hybrid Cells; D008297:Male; D051379:Mice; D012150:Polymorphism, Restriction Fragment Length; D015183:Restriction Mapping; D014998:Y Chromosome
D015342:DNA Probes