Assessment of the biological activity of cyclosporine metabolites using the human JURKAT cell line.
Freed
B M
BM
Department of Surgery, Albany Medical College, New York 12208.
Stevens
C
C
Brooks
C
C
Cramer
S
S
Lempert
N
N
Rosano
T G
TG
D002460:Cell Line; D003524:Cyclosporins / Q000378:metabolism* / Q000494:pharmacology; D006801:Humans; D066298:In Vitro Techniques; D007376:Interleukin-2 / Q000096:biosynthesis; D008213:Lymphocyte Activation / Q000187:drug effects; D008775:Methylprednisolone / Q000494:pharmacology; D013329:Structure-Activity Relationship; D013601:T-Lymphocytes / Q000187:drug effects*
D003524:Cyclosporins; D007376:Interleukin-2; C051527:cyclosporine metabolite M17; D008775:Methylprednisolone