title: Evaluation of interconversion between (R)- and (S)-enantiomers of beta-aminoisobutyrate.
abstract: The conversion of (R)- to (S)-beta-aminoisobutyrate was observed in the presence of D-3-aminoisobutyrate-pyruvate aminotransferase, aminobutyrate aminotransferase, pyruvate and L-glutamate. The reverse reaction was also found in the presence of 2-oxoglutarate and L-alanine. Neither D-3-aminoisobutyrate-pyruvate aminotransferase nor aminobutyrate aminotransferase revealed a racemase activity of the enantiomorphs.
authors.affiliation: Laboratory of Nutritional Chemistry, Faculty of Nutrition, Kobe-Gakuin University, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Tamaki
authors.forename: M
authors.initials: M
authors.lastname: Kaneko
authors.forename: M
authors.initials: M
authors.lastname: Kikugawa
authors.forename: S
authors.initials: S
authors.lastname: Fujimoto
mesh_terms: D000612:4-Aminobutyrate Transaminase / Q000378:metabolism*; D000409:Alanine / Q000378:metabolism; D000621:Aminoisobutyric Acids / Q000378:metabolism*; D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D002851:Chromatography, High Pressure Liquid; D005971:Glutamates / Q000378:metabolism; D018698:Glutamic Acid; D007656:Ketoglutaric Acids / Q000378:metabolism; D011773:Pyruvates / Q000378:metabolism; D019289:Pyruvic Acid; D051381:Rats; D013237:Stereoisomerism; D000637:Transaminases / Q000378:metabolism*
chemical_list: D000621:Aminoisobutyric Acids; D005971:Glutamates; D007656:Ketoglutaric Acids; D011773:Pyruvates; D018698:Glutamic Acid; D019289:Pyruvic Acid; D000637:Transaminases; D000612:4-Aminobutyrate Transaminase; D000409:Alanine; C033435:3-aminoisobutyric acid