title: Neurobehavioral changes produced by developmental exposure to benzodiazepines.
abstract: The results reported in this review show that prenatal and/or postnatal administration of benzodiazepines, at dose levels below those associated with overt signs of neurotoxicity, produces both short- and long-term alterations in rats. Most of these behavioral changes are characterized by altered activity patterns and emotional/motivational responsiveness to environmental challenges.
authors.affiliation: Institute of Pharmacology, University of Bari, Italy.
authors.forename: M A
authors.initials: MA
authors.lastname: De Salvia
authors.forename: R
authors.initials: R
authors.lastname: Cagiano
authors.forename: C
authors.initials: C
authors.lastname: Lacomba
authors.forename: V
authors.initials: V
authors.lastname: Cuomo
mesh_terms: D000818:Animals; D014151:Anti-Anxiety Agents / Q000378:metabolism / Q000633:toxicity*; D001522:Behavior, Animal / Q000187:drug effects*; D001569:Benzodiazepines; D005314:Embryonic and Fetal Development / Q000187:drug effects*; D005260:Female; D006801:Humans; D008431:Maternal-Fetal Exchange; D011247:Pregnancy
chemical_list: D014151:Anti-Anxiety Agents; D001569:Benzodiazepines