Inherited diseases of bone density in children.
In this article the radiographic manifestations of various genetic diseases predominately affecting bone mineralization are considered. Osteogenesis imperfecta and other diseases of diffuse osteopenia, hereditary rickets and rachiticlike conditions, and osteopetrosis and other diseases of increased bone density are emphasized. Recognition of the radiographic manifestations allows accurate diagnosis, therapeutic intervention when possible, and determination of recurrence risk for genetic counseling.
Herman
T E
TE
Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri.
McAlister
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WH
D015519:Bone Density; D001848:Bone Diseases, Developmental / Q000000981:diagnostic imaging / Q000235:genetics / Q000503:physiopathology; D001851:Bone Diseases, Metabolic / Q000000981:diagnostic imaging* / Q000235:genetics / Q000503:physiopathology; D002648:Child; D006801:Humans; D007231:Infant, Newborn; D011859:Radiography; D012279:Rickets / Q000000981:diagnostic imaging / Q000235:genetics / Q000503:physiopathology