Effect of bacterial pyrogen on three lizard species.
1. Three lizard species (Callopistes maculatus, Gerrhosaurus major, and Varanus exanthematicus) were tested for their response to intraperitoneal injection of alcohol-killed Aeromonas sobria. 2. A paired experimental design, in which each animal received an injection of sterile saline and 1 x 10(10) A. sobria, was utilized. 3. C. maculatus demonstrated a statistically significant increase in mean selected body temperature (MSBT) after bacteria injection. 4. G. major and V. exanthematicus did not demonstrate a statistically significant increase in MSBT. 5. C. maculatus is the first lizard species outside of the family Iguanidae to exhibit a febrile response to bacterial pyrogen.
Hallman
G M
GM
Department of Biology, California State University, Los Angeles 90032.
Ortega
C E
CE
Towner
M C
MC
Muchlinski
A E
AE
D000333:Aeromonas / Q000378:metabolism; D000818:Animals; D001831:Body Temperature / Q000187:drug effects; D008116:Lizards / Q000502:physiology*; D011749:Pyrogens / Q000494:pharmacology*; D013045:Species Specificity
D011749:Pyrogens