title: [Comparison of the incidence of bleeding of 2 anesthetic technics midazolam-alfentanil versus propofol-alfentanil during treatment of otospongiosis].
abstract: This study was performed to compare the incidence of bleeding associated with two anaesthetic techniques during otolaryngological microsurgery. Twenty-eight venous interpositions for otospongiosis have been carried out at random either under local anaesthesia combined with light sedation (midazolam 0.1 mg.kg-1 and alfentanil 0 micrograms.kg-1) or using general anaesthesia (propofol 2.5 mg.kg-1, then 9 mg.kg-1.hr-1 and alfentanil 30 micrograms.kg-1, then 15 micrograms.kg-1). The patients' lungs were mechanically ventilated. Every ten minutes, heart rate, arterial blood pressure and FETCO2 were observed. Bleeding was assessed on a four-point scale and evaluated according to its duration and the annoyance that it caused. General anaesthesia was clinically better tolerated. Heart rate and arterial blood pressure were lower than with general anaesthesia. The end-expiratory CO2 was 4.7 +/- 0.2 per cent. Bleeding was less frequent, lasted less time, but when it occurred the surgical disturbance was identical in the two groups. General anaesthesia produced a less bloody operating field and local anaesthesia required the cooperation of the patient.
authors.affiliation: Département d'Anesthésie-Réanimation, CHRU Hôpital Central, Nancy, France.
authors.forename: D
authors.initials: D
authors.lastname: Boisson-Bertrand
authors.forename: J
authors.initials: J
authors.lastname: Manel
mesh_terms: D000328:Adult; D015760:Alfentanil; D000771:Anesthesia, Intravenous; D000772:Anesthesia, Local; D016063:Blood Loss, Surgical / Q000706:statistics & numerical data*; D001794:Blood Pressure; D005260:Female; D006339:Heart Rate; D006488:Hemostasis, Surgical; D006801:Humans; D015994:Incidence; D008012:Lidocaine; D008297:Male; D008874:Midazolam; D010040:Otosclerosis / Q000601:surgery*; D015742:Propofol; D013997:Time Factors
chemical_list: D015760:Alfentanil; D008012:Lidocaine; D008874:Midazolam; D015742:Propofol