title: [Malignant skin and soft tissue tumors--function preserving surgery--pathomorphologic aspects].
abstract: Special aspects of the localization and spontaneous regression of primaries of malignant melanoma, further more aspects of the pTNM-system as well as problems concerning perfusion therapy are pointed out and discussed. In the following the different biology of squamous cell and basal cell cancer dependent also on the localization of the primaries is described and discussed. Concerning the soft tissue tumor part immunohistochemical methods for the management of differential diagnosis are demonstrated and evaluated. These methods can be used for the delineation of extranodal Hodgkin and non-Hodgkin lymphoma infiltration from soft tissue tumors and in the differential diagnosis of polymorphous, spindle cell and epitheloid differentiated soft tissue tumors. Finally the problem of tumor grading and new grading systems (score) according to Coindre et al. are demonstrated and discussed.
authors.affiliation: Zentrum Pathologie, Universitäts-Klinikum, Göttingen.
authors.forename: A
authors.initials: A
authors.lastname: Schauer
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D002280:Basal Cell Carcinoma / Q000473:pathology / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery; D003131:Combined Modality Therapy; D006801:Humans; D007150:Immunohistochemistry; D008207:Lymphatic Metastasis; D008545:Melanoma / Q000473:pathology / Q000601:surgery; D009367:Neoplasm Staging; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*; D012983:Soft Tissue Neoplasms / Q000473:pathology* / Q000601:surgery*; D013518:Surgery, Plastic / Q000379:methods*
chemical_list: D014408:Biomarkers, Tumor