Replication status of the fragile X chromosome and its implications for reproductive performance in the Indian mole rat (Nesokia indica).
In all fertile females the fragile X chromosome was almost always late replicating (inactive) in an average 82% of cells whereas in infertile females, it was early replicating (active) in about the same percentage of cells. These observations strongly suggest a correlation between the replication (activity) status of the fragile X chromosome and reproductive performance.
Tewari
R
R
Department of Zoology, University of Delhi, India.
Rao
S R
SR
D000818:Animals; D002873:Chromosome Fragility; D005260:Female; D012098:Reproduction / Q000502:physiology*; D012377:Rodentia / Q000502:physiology*; D014960:X Chromosome / Q000502:physiology* / Q000648:ultrastructure