title: [Pathophysiology and classification of adhesions].
abstract: The central issue in the pathophysiology of adhesions is the shift of the dynamic balance between fibrinolysis and fibrinogenesis to the side of fibrinogenesis. Permanent adhesions with the most varied morphology are formed by invasion of the fibrin network by fibroblasts and fibroid organization. Their classification by four degrees of severity is based on histological and morphological criteria. This classification has been shown useful and practicable for the objective examination and evaluation of relaparotomies in connection with expert opinion reports and animal experiments on adhesion research.
authors.affiliation: Chirurgische Klinik und Poliklinik im Klinikum Steglitz, Freien Universität Berlin.
authors.forename: H V
authors.initials: HV
authors.lastname: Zühlke
authors.forename: E M
authors.initials: EM
authors.lastname: Lorenz
authors.forename: E M
authors.initials: EM
authors.lastname: Straub
authors.forename: V
authors.initials: V
authors.lastname: Savvas
mesh_terms: D000005:Abdomen / Q000473:pathology / Q000601:surgery*; D000818:Animals; D006801:Humans; D010537:Peritoneum / Q000473:pathology / Q000503:physiopathology; D011183:Postoperative Complications / Q000145:classification* / Q000473:pathology / Q000503:physiopathology*; D013536:Suture Techniques; D000267:Tissue Adhesions / Q000145:classification* / Q000473:pathology / Q000503:physiopathology*; D014945:Wound Healing / Q000502:physiology