title: Immunological reactions of pigs during long-term beta-adrenergic treatment.
abstract: Experiments were performed to determine the effects of the beta-adrenergic agonist Ro 16-8714 on the immune system of finishing pigs fed an adequate or a low-protein diet. Growth rate, nitrogen and fat retention, body composition as well as spleen weight were influenced by both beta-agonist and/or protein level, as expected. However, lymphocyte stimulation with Concanavalin A and phytohemagglutinine in vitro or in vivo antibody production against horse red blood cells were not changed by the beta-agonist in pigs fed sufficient or insufficient amounts of protein.
authors.affiliation: Institute of Animal Breeding, School of Veterinary Medicine, University of Berne, Switzerland.
authors.forename: H
authors.initials: H
authors.lastname: Hirni
authors.forename: S
authors.initials: S
authors.lastname: Lazary
authors.forename: J
authors.initials: J
authors.lastname: Blum
mesh_terms: D015078:2-Hydroxyphenethylamine / Q000031:analogs & derivatives / Q000494:pharmacology*; D000318:Adrenergic beta-Agonists / Q000494:pharmacology*; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D004044:Dietary Proteins / Q000008:administration & dosage*; D007111:Immunity, Cellular / Q000187:drug effects; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D010627:Phenethylamines / Q000494:pharmacology*; D013552:Swine / Q000276:immunology*
chemical_list: D000318:Adrenergic beta-Agonists; D004044:Dietary Proteins; D010627:Phenethylamines; D015078:2-Hydroxyphenethylamine; C045606:4-(3-(bis(beta-hydroxyphenethyl)amino)butyl)benzamide