Multiple endocrine neoplasia type 1--presenting with impotence.
A 35-year old man presented with a 4-year history of impotence. His past history was significant for hypercalcaemia, bilateral pyelolithotomies for renal calculi and parathyroidectomy for hyperparathyroidism. He had an episode of haemetemesis and malaena a year before being seen here. Endocrine investigations revealed hyperprolactinemia, hypergastrinemia and increased basal acid output. Magnetic resonance imaging of the brain was indicative of a pituitary microadenoma. Computed tomographic scan of the abdomen revealed a bulky pancreas which was suggestive of a gastrin-secreting islet cell tumour. This case illustrates an unusual presentation of multiple endocrine neoplasia type 1 (MEN-1) with impotence and hyperprolactinemia. A short review of the literature was done.
Lye
W C
WC
Department of Medicine, National University Hospital, Singapore.
Lee
K O
KO
Tay
H H
HH
D000236:Adenoma / Q000150:complications / Q000175:diagnosis*; D000328:Adult; D007172:Erectile Dysfunction / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D006966:Hyperprolactinemia / Q000150:complications / Q000175:diagnosis*; D008297:Male; D009377:Multiple Endocrine Neoplasia / Q000150:complications / Q000175:diagnosis*; D010911:Pituitary Neoplasms / Q000150:complications / Q000175:diagnosis*; D015043:Zollinger-Ellison Syndrome / Q000150:complications / Q000175:diagnosis