title: Cell membrane lipid composition in CAPD patients.
abstract: We analyzed the erythrocyte membrane lipid composition in 11 non-diabetic CAPD patients on treatment for 3-78 months and in a control group of 12 subjects. The mean total values of both saturated fatty acids and unsaturated fatty acids were not statistically different in CAPD patients and in controls but the composition of fatty acids of in cell membranes was altered. In fact, CAPD patients had a higher percentage of monounsaturated fatty acids and a lower percentage of polyunsaturated fatty acids than controls. This increase MUFA/PUFA ratio might reflect either a preferential cell membrane uptake of MUFA or a relative PUFA deficiency due to an increased lipid peroxidation.
authors.affiliation: Institute of Nephrology, University of Verona, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Lupo
authors.forename: P
authors.initials: P
authors.lastname: Bernich
authors.forename: A
authors.initials: A
authors.lastname: Fabris
authors.forename: P
authors.initials: P
authors.lastname: Zanni
authors.forename: M T
authors.initials: MT
authors.lastname: Trevisan
authors.forename: S
authors.initials: S
authors.lastname: Ferrari
authors.forename: A
authors.initials: A
authors.lastname: Bassi
authors.forename: D
authors.initials: D
authors.lastname: Girelli
authors.forename: O
authors.initials: O
authors.lastname: Olivieri
authors.forename: G
authors.initials: G
authors.lastname: Maschio
mesh_terms: D000368:Aged; D004910:Erythrocyte Membrane / Q000737:chemistry*; D005229:Fatty Acids, Monounsaturated / Q000032:analysis; D005231:Fatty Acids, Unsaturated / Q000032:analysis; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000628:therapy*; D008055:Lipids / Q000097:blood; D008297:Male; D008563:Membrane Lipids / Q000032:analysis*; D010531:Peritoneal Dialysis, Continuous Ambulatory; D013997:Time Factors
chemical_list: D005229:Fatty Acids, Monounsaturated; D005231:Fatty Acids, Unsaturated; D008055:Lipids; D008563:Membrane Lipids