title: [Treatment with somatostatin of variceal digestive hemorrhage: a one-year prospective].
abstract: Twenty-two patients with variceal bleeding were treated with somatostatin, receiving a bolus of 250 mcg followed by an infusion at a rate of 250 mcg/hour. Bleeding stopped in sixteen patients (72.7%). Definitive control was attained in 13 patients (59.2%). Mortality was 31.8%. Somatostatin was not effective in patients with large varices, jet bleeding and hepatic insufficiency. Only minor side effects were recorded in four patients (18.2%).
authors.affiliation: Sección de Aparato Digestivo, Servicio de Medicina Interna, Hospital General Yagüe, Burgos.
authors.forename: L
authors.initials: L
authors.lastname: Yuguero del Moral
authors.forename: A J
authors.initials: AJ
authors.lastname: López Morante
authors.forename: J L
authors.initials: JL
authors.lastname: Martín Lorente
authors.forename: C
authors.initials: C
authors.lastname: Ojeda Giménez
mesh_terms: D000328:Adult; D000368:Aged; D004932:Esophageal and Gastric Varices / Q000150:complications*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013004:Somatostatin / Q000627:therapeutic use*
chemical_list: D013004:Somatostatin