Strategies and governmental regulations.
An overview of testing strategies for the detection of genotoxins under OECD Guidelines and the EEC Directive 79/831 (VI Amendment) is outlined. The viewpoint of the Italian National Advisory Committee on Toxicology is also presented. In this context, the main issues of Genetic Toxicology (e.g., role of tests, tests recommended, classification of mutagens) are discussed.
Carere
A
A
Istituto Superiore di Sanità, Rome, Italy.
Benigni
R
R
D000818:Animals; D006077:Government Agencies; D006285:Health Planning; D006287:Health Planning Guidelines; D006291:Health Policy; D007558:Italy; D009152:Mutagenicity Tests; D006113:United Kingdom