title: Search for cellular phosphorylation products of D-allose.
abstract: The all-cis hexose D-allose, fed to hamster fibroblast cultures over 14-20 hr, brings about a striking down-regulation of hexose transport. This down-regulation by allose is inhibited by 2,4-dinitrophenol. By using D-[14C]allose and thin-layer chromatography, two types of products accumulated that have been identified as allose and allose phosphate. We suspect that allose phosphate might be the down-regulator.
authors.affiliation: Chemistry Department, Boston University, MA 02215.
authors.forename: D B
authors.initials: DB
authors.lastname: Ullrey
authors.forename: H M
authors.initials: HM
authors.lastname: Kalckar
mesh_terms: D000818:Animals; D001711:Biotransformation; D002250:Carbon Radioisotopes; D002460:Cell Line; D002855:Chromatography, Thin Layer; D006224:Cricetinae; D003412:Cricetulus; D005947:Glucose / Q000378:metabolism*; D007700:Kinetics; D008168:Lung; D010766:Phosphorylation; D011865:Radioisotope Dilution Technique
chemical_list: D002250:Carbon Radioisotopes; C002055:allose; D005947:Glucose