title: Demonstration of heat production associated with spreading depression in the amphibian retina.
abstract: Using thin film of synthetic pyroelectric material, polyvinylidene fluoride, sensitive heat-sensors were constructed for the purpose of detecting heat production associated with the phenomenon of spreading depression in isolated amphibian retinae. Measurements with these sensors revealed the existence of large heat production, which closely follows the electrical sign of spreading depression. Studies of the effects of chemical agents known to affect spreading depression have demonstrated the usefulness of heat measurements.
authors.affiliation: Laboratory of Cell Biology, National Institute of Mental Health, Bethesda, Maryland 20892.
authors.forename: I
authors.initials: I
authors.lastname: Tasaki
authors.forename: P M
authors.initials: PM
authors.lastname: Byrne
mesh_terms: D000818:Animals; D013181:Cortical Spreading Depression; D004558:Electric Stimulation; D006358:Hot Temperature; D011892:Rana catesbeiana; D012160:Retina / Q000502:physiology*