Quinine-induced disseminated intravascular coagulation.
Recurrent disseminated intravascular coagulation occurred in 3 women after ingestion of quinine tablets for cramp. All had circulating quinine-dependent antibodies to platelets and in 2 there was initial evidence of antibody consumption, with low titres that rose steeply over the next few days and remained high for many months.
Spearing
R L
RL
Department of Haematology, Christchurch Hospital, New Zealand.
Hickton
C M
CM
Sizeland
P
P
Hannah
A
A
Bailey
R R
RR
D000293:Adolescent; D000368:Aged; D004211:Disseminated Intravascular Coagulation / Q000139:chemically induced* / Q000276:immunology; D005260:Female; D006801:Humans; D009120:Muscle Cramp / Q000188:drug therapy / Q000276:immunology; D011803:Quinine / Q000009:adverse effects* / Q000276:immunology
D011803:Quinine