title: A survey of endocrine cells in the pancreas of the echidna (Tachyglossus aculeatus) with special reference to pancreatic motilin cells.
abstract: Pancreatic endocrine cells were examined in a primitive egg-laying mammal, the echidna, using immunohistochemistry. Immunoreactive endocrine cells were observed using antisera to insulin, glucagon, somatostatin, avian pancreatic polypeptide and bovine pancreatic polypeptide. In addition, motilin-immunoreactive cells were identified in both the endocrine and exocrine pancreas of pouch-young and adult echidnas using three types of motilin antisera. Since the motilin-immunoreactive cells did not cross-react with any other pancreatic hormones tested, they are identified as an independent endocrine cell type.
authors.affiliation: Department of Veterinary Anatomy, Obihiro University of Agriculture and Veterinary Medicine, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Yamada
authors.forename: W J
authors.initials: WJ
authors.lastname: Krause
authors.forename: N
authors.initials: N
authors.lastname: Edwin
authors.forename: T
authors.initials: T
authors.lastname: Mochizuki
authors.forename: N
authors.initials: N
authors.lastname: Yanaihara
mesh_terms: D001078:APUD Cells / Q000166:cytology*; D000818:Animals; D005934:Glucagon / Q000032:analysis; D007106:Immune Sera / Q000276:immunology; D007328:Insulin / Q000032:analysis; D007515:Islets of Langerhans / Q000166:cytology; D009037:Motilin / Q000032:analysis*; D010179:Pancreas / Q000737:chemistry / Q000166:cytology*; D010191:Pancreatic Polypeptide / Q000032:analysis; D013004:Somatostatin / Q000032:analysis; D004442:Tachyglossidae / Q000033:anatomy & histology* / Q000378:metabolism
chemical_list: D007106:Immune Sera; D007328:Insulin; D013004:Somatostatin; D009037:Motilin; D010191:Pancreatic Polypeptide; D005934:Glucagon