title: Localization and quantitation of tritiated compounds in tissue sections with a gaseous detector of beta particles: comparison with film autoradiography.
abstract: Quantitative analysis of tritium polymer standards and of brain sections labeled with tritiated vasopressin was carried out by using a gaseous detector of beta particles designed for this purpose. The gaseous detector showed major advantages compared with film autoradiography: the linearity and the large dynamic range of intensity measurements as well as the short time needed for data acquisition.
authors.affiliation: Department of Physiology, University Medical Centre, Geneva, Switzerland.
authors.forename: E
authors.initials: E
authors.lastname: Tribollet
authors.forename: J J
authors.initials: JJ
authors.lastname: Dreifuss
authors.forename: G
authors.initials: G
authors.lastname: Charpak
authors.forename: W
authors.initials: W
authors.lastname: Dominik
authors.forename: N
authors.initials: N
authors.lastname: Zaganidis
mesh_terms: D000818:Animals; D001127:Arginine Vasopressin / Q000378:metabolism; D001345:Autoradiography / Q000379:methods; D001921:Brain / Q000166:cytology*; D011865:Radioisotope Dilution Technique; D051381:Rats; D011945:Receptors, Angiotensin / Q000032:analysis*; D017483:Receptors, Vasopressin; D014316:Tritium
chemical_list: D011945:Receptors, Angiotensin; D017483:Receptors, Vasopressin; D014316:Tritium; D001127:Arginine Vasopressin