Study of reproductive function in persons occupationally exposed to 2,4-dichlorophenoxyacetic acid (2,4-D).
We studied the reproductive function of 32 male farm sprayers who were exposed to 2,4-D. Sperm analysis was made after 4 days of sexual inactivity. Parameters analyzed were volume, sperm count, mobility and morphology. Exposure level was estimated by measuring the concentration of 2,4-D in the urine. Significant levels of asthenospermia, necrospermia and teratospermia were found in exposed workers compared with unexposed controls. Over time, asthenospermia and necrospermia diminished but the abnormal spermatozoa (teratospermia) continued.
Lerda
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Hospital Regional Dr. Abel Ayerza, Marcos Juárez, Argentina.
Rizzi
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D015084:2,4-Dichlorophenoxyacetic Acid / Q000633:toxicity* / Q000652:urine; D006801:Humans; D008297:Male; D016273:Occupational Exposure; D012098:Reproduction / Q000187:drug effects*; D013076:Sperm Count / Q000187:drug effects; D013081:Sperm Motility / Q000187:drug effects; D013094:Spermatozoa / Q000187:drug effects
D015084:2,4-Dichlorophenoxyacetic Acid