title: Disseminated histoplasmosis presenting as an ulcerated verrucous plaque in a human immunodeficiency virus-infected man. Report of a case possibly involving human-to-human transmission of histoplasmosis.
abstract: A 46-year-old homosexual man with disseminated histoplasmosis and human immunodeficiency virus (HIV) infection had a histoplasmosis-related ulcerated verrucous plaque above his left upper lip; systemic and cutaneous disease manifestations of histoplasmosis resolved with daily ketoconazole therapy. Disseminated histoplasmosis, with similar cutaneous features, also was present in his HIV-seropositive male sexual partner. The possibility of human-to-human transmission of histoplasmosis between these patients is considered and the skin lesions of systemic fungal infections in HIV-infected patients are reviewed.
authors.affiliation: Department of Dermatology, College of Physicians and Surgeons of Columbia University, New York, New York.
authors.forename: P R
authors.initials: PR
authors.lastname: Cohen
authors.forename: J L
authors.initials: JL
authors.lastname: Held
authors.forename: M E
authors.initials: ME
authors.lastname: Grossman
authors.forename: M J
authors.initials: MJ
authors.lastname: Ross
authors.forename: D N
authors.initials: DN
authors.lastname: Silvers
mesh_terms: D003881:Dermatomycoses / Q000150:complications* / Q000188:drug therapy / Q000473:pathology / Q000635:transmission; D015658:HIV Infections / Q000150:complications*; D006660:Histoplasmosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology / Q000635:transmission; D006801:Humans; D007654:Ketoconazole / Q000627:therapeutic use; D008046:Lip; D008297:Male; D008875:Middle Aged
chemical_list: D007654:Ketoconazole