Propylene glycol dermatitis.
Propylene glycol is a commonly used vehicle for topical preparations. Although it is well suited for this purpose, it is capable of producing both primary irritant skin reactions and allergic sensitization. The literature on propylene glycol is reviewed, with particular attention to the nature of these adverse cutaneous effects. Guidelines for patients sensitive to propylene glycol are discussed.
Catanzaro
J M
JM
Department of Dermatology, Medical College of Georgia, Augusta 30912-2900.
Smith
J G
JG
D000279:Administration, Cutaneous; D003877:Dermatitis, Contact / Q000209:etiology*; D006801:Humans; D014677:Pharmaceutical Vehicles / Q000627:therapeutic use; D011409:Propylene Glycols / Q000009:adverse effects*; D012871:Skin Diseases / Q000188:drug therapy
D014677:Pharmaceutical Vehicles; D011409:Propylene Glycols