title: Management of arginine monohydrochloride extravasation in the forearm.
abstract: We initially observed our patient, who had subcutaneous arginine monohydrochloride extravasation in the volar forearm, until his wound demarcation was complete. After wound demarcation, we proceeded with debridement and partial-thickness skin grafting. Upper extremity function was totally normal 3 months after this therapy. This is the first case report in the literature that describes a child with an arginine monohydrochloride-induced extravasation necrosis.
authors.affiliation: Division of Plastic and Reconstructive Surgery, University of Tennessee, Chattanooga.
authors.forename: G L
authors.initials: GL
authors.lastname: Baker
authors.forename: J D
authors.initials: JD
authors.lastname: Franklin
mesh_terms: D000592:Amino Acid Metabolism, Inborn Errors / Q000188:drug therapy; D001120:Arginine / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D001124:Argininosuccinate Synthase / Q000172:deficiency; D002648:Child; D003646:Debridement; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000601:surgery*; D005542:Forearm; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D009336:Necrosis; D012867:Skin / Q000473:pathology; D016038:Skin Transplantation
chemical_list: D001120:Arginine; D001124:Argininosuccinate Synthase