Growth of Igbo-Ora virus in some tissue cultures.
VERO, MRC5, MDCK, and MA104 cells were tested for their ability to support the growth of Igbo-Ora virus. In VERO and MRC5 cell cultures the virus replicated to high titres causing apparent cytopathic effects (CPE) (cell rounding and complete lysis) and formation of complement fixing antigens. The virus grew to lower infectious titre in MDCK and MA104 cell cultures in which CPE was limited to cell rounding only.
Olaleye
O D
OD
Department of Virology, College of Medicine, University College Hospital, University of Ibadan, Nigeria.
Omilabu
S A
SA
Baba
S S
SS
D000524:Alphavirus / Q000254:growth & development*; D000818:Animals; D046508:Culture Techniques; D003588:Cytopathogenic Effect, Viral; D006801:Humans; D014776:Virus Cultivation / Q000379:methods*