title: 3-Phenyl analogues of 2-[[[2-(2,6-dimethoxyphenoxy)ethyl]amino]-methyl]-1,4-benzodioxan (WB 4101) as highly selective alpha 1-adrenoceptor antagonists.
authors.affiliation: Department of Chemical Sciences, University of Camerino, Italy.
authors.forename: W
authors.initials: W
authors.lastname: Quaglia
authors.forename: M
authors.initials: M
authors.lastname: Pigini
authors.forename: M
authors.initials: M
authors.lastname: Giannella
authors.forename: C
authors.initials: C
authors.lastname: Melchiorre
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D001555:Benzene Derivatives / Q000737:chemistry / Q000494:pharmacology; D001667:Binding, Competitive; D004146:Dioxanes / Q000737:chemistry / Q000494:pharmacology*; D008297:Male; D015394:Molecular Structure; D051381:Rats; D013329:Structure-Activity Relationship; D014649:Vas Deferens / Q000187:drug effects
chemical_list: D000317:Adrenergic alpha-Antagonists; D001555:Benzene Derivatives; D004146:Dioxanes; C066277:phendioxan; C010654:(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane