Serial neurobehavioral assessments in preterm infants.
The purpose of this study was to compare serial neurobehavioral assessments in a sample of preterm infants with intraventricular hemorrhage (IVH) to those of a group of unaffected preterm infants. Of the 30 infants included in the study, 5 infants had a grade III or IV/VI intraventricular hemorrhage. Infants with IVH demonstrated more abnormalities in mental status and a cluster of abnormal neurologic findings (persistent ankle clonus, tremulousness, and brisk deep tendon reflexes). Of the 30 infants, 20 infants were included in a brain metabolism study. Infants who had experienced an IVH had significantly different brain metabolism findings, as measured by nuclear magnetic resonance spectroscopy (NMR). There was a significant correlation between one measure of brain metabolism (PCr/PI) and the neurobehavioral assessment rating for infants with IVH.
Medoff-Cooper
B
B
University of Pennsylvania, School of Nursing, Philadelphia.
Delivoria-Papadopoulos
M
M
Brooten
D
D
D001921:Brain / Q000378:metabolism; D002543:Cerebral Hemorrhage / Q000378:metabolism / Q000503:physiopathology*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000378:metabolism / Q000502:physiology*; D007235:Infant, Premature, Diseases / Q000175:diagnosis / Q000378:metabolism / Q000503:physiopathology*; D009682:Magnetic Resonance Spectroscopy; D009422:Nervous System Diseases / Q000175:diagnosis; D009483:Neuropsychological Tests / Q000379:methods