title: The same myosin isoforms are found in the female and male sexually dimorphic levator ani muscle of the rat, but their postnatal transitions are not synchronous.
abstract: The levator ani of the female adult rat is greatly atrophied in comparison to the same muscle in males. In the present study, the female levator ani was, nevertheless, found to contain type IIb myosin isoforms similar to those contained in the male muscle. These adult type isoforms were, however, synthesized later in the female than in the male levator ani: the half-transition times of the myosin transition curve were 20 days postnatal in the male and 35 days postnatal in the female. The transition curves for castrated and uncastrated male rats were the same. Thus, the presence of male gonadal hormones apparently did not affect the myosin transition.
authors.affiliation: URA CNRS 1131, Université Paris-Sud, Orsay, France.
authors.forename: A
authors.initials: A
authors.lastname: d'Albis
authors.forename: R
authors.initials: R
authors.lastname: Couteaux
authors.forename: C
authors.initials: C
authors.lastname: Janmot
authors.forename: J C
authors.initials: JC
authors.lastname: Mira
mesh_terms: D000818:Animals; D015180:Electrophoresis, Gel, Two-Dimensional; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D008297:Male; D024510:Muscle Development; D009132:Muscles / Q000033:anatomy & histology*; D009218:Myosins / Q000378:metabolism*; D010388:Pelvis; D051381:Rats; D011919:Rats, Inbred Strains; D012727:Sex Characteristics
chemical_list: D009218:Myosins