A lethal complication of papaverine-induced priapism.
A large series of patients was treated for impotence with intracorporeal injections of papaverine and phentolamine with no major complications and no deaths reported. We report on a 45-year-old black man with advanced multiple sclerosis who died after such therapy. When the first self-administered injection of phentolamine and papaverine failed to produce an adequate erection the patient injected a second dose that resulted in priapism and death of massive pulmonary embolism.
Hashmat
A I
AI
Brooklyn Hospital Center, New York.
Abrahams
J
J
Fani
K
K
Nostrand
I
I
D004305:Dose-Response Relationship, Drug; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications; D010208:Papaverine / Q000008:administration & dosage / Q000009:adverse effects*; D010413:Penis / Q000098:blood supply / Q000473:pathology; D011317:Priapism / Q000139:chemically induced* / Q000473:pathology; D011655:Pulmonary Embolism / Q000139:chemically induced / Q000473:pathology; D012646:Self Administration / Q000009:adverse effects; D013927:Thrombosis / Q000139:chemically induced / Q000473:pathology
D010208:Papaverine