Cloning of rat lutropin (LH) receptor analogs lacking the soybean lectin domain.
cDNAs coding for rat ovarian luteinizing hormone receptor analogs lacking three of the leucine repeats were detected in a library which had been prepared from rat luteal tissue undergoing human chorionic gonadotropin-induced luteinization. These leucine repeats correspond to amino acids 206-267 and contain the portion of the receptor that is homologous to the soybean lectin. The cDNA library also contained a receptor analog lacking amino acids 321-700 which code for the transmembrane domain. S-1 mapping suggests that this latter form constitutes approximately half of all receptor-related mRNA.
Bernard
M P
MP
Department of OBGYN, Robert Wood Johnson (Rutgers) Medical School, Piscataway, NJ 08854.
Myers
R V
RV
Moyle
W R
WR
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D001665:Binding Sites; D003001:Cloning, Molecular; D003338:Corpus Luteum / Q000378:metabolism*; D004247:DNA / Q000235:genetics; D005260:Female; D037102:Lectins / Q000378:metabolism; D008969:Molecular Sequence Data; D010062:Ovulation Induction; D010446:Peptide Fragments / Q000235:genetics; D037121:Plant Lectins; D011061:Poly A / Q000235:genetics; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger / Q000235:genetics; D051381:Rats; D011974:Receptors, LH / Q000235:genetics* / Q000378:metabolism; D012689:Sequence Homology, Nucleic Acid; D030262:Soybean Proteins; D010835:Phytohemagglutinins
D004247:DNA; D037102:Lectins; D010446:Peptide Fragments; D037121:Plant Lectins; D011061:Poly A; D012333:RNA, Messenger; D011974:Receptors, LH; D030262:Soybean Proteins; C028824:soybean lectin; D010835:Phytohemagglutinins