Imprinting a determined state into the chromatin of Drosophila.
The Polycomb gene of Drosophila melanogaster is a member of a class of genes involved in the clonal transmission of the repressed state of bomeotic regulatory genes through development. Genetic evidence, and the finding of a molecular similarity between the Polycomb protein and a heterochromatin-associated protein of Drosophila, suggest that this mechanism of repression might be imprinted in the structure of the chromatin, rather than being sustained through the action of diffusible regulatory factors.
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Zentrum für Molekulare Biologie, Universität Heidelberg, FRG.
D000595:Amino Acid Sequence; D000818:Animals; D002843:Chromatin / Q000648:ultrastructure*; D002875:Chromosomes / Q000648:ultrastructure; D004330:Drosophila / Q000235:genetics*; D005786:Gene Expression Regulation; D005801:Genes, Homeobox; D008969:Molecular Sequence Data
D002843:Chromatin