title: Beta-lactamase-negative, methicillin-resistant Staphylococcus aureus in a newborn nursery: report of an outbreak and laboratory investigations.
abstract: An outbreak of skin infection caused by a beta-lactamase-negative strain of methicillin-resistant Staphylococcus aureus (MRSA) occurred during a five-week period in a newborn nursery. Twelve babies, two mothers and two members of staff were involved. One baby had a diagnosis of staphylococcal scalded skin syndrome and two others required treatment with antibiotics. The infecting strain produced exfoliative toxin A. It was thought that it had been introduced from a different maternity unit by a nasal carrier. Laboratory investigations tended to support this hypothesis.
authors.affiliation: Staphylococcus Reference Laboratory, Central Public Health Laboratory, London.
authors.forename: J F
authors.initials: JF
authors.lastname: Richardson
authors.forename: A H
authors.initials: AH
authors.lastname: Quoraishi
authors.forename: B J
authors.initials: BJ
authors.lastname: Francis
authors.forename: R R
authors.initials: RR
authors.lastname: Marples
mesh_terms: D001434:Bacteriophage Typing; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control; D004196:Disease Outbreaks; D005083:Exfoliatins / Q000096:biosynthesis; D006801:Humans; D007231:Infant, Newborn; D016106:Methicillin Resistance; D009725:Nurseries, Hospital; D010957:Plasmids; D015183:Restriction Mapping; D013207:Staphylococcal Skin Infections / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control; D013211:Staphylococcus aureus / Q000145:classification / Q000235:genetics; D014852:Wales / Q000453:epidemiology
chemical_list: D005083:Exfoliatins