title: The presence of platelet-activating factor-like activity in human spermatozoa.
abstract: Evidence is provided for the existence of platelet-activating factor (PAF)-like activity in the lipid extracts of human spermatozoa. The PAF content of human spermatozoa based on [3H]-serotonin release from washed rabbit platelets was noted to be 1.45 pmol/10(8) sperm cells in highly purified motile spermatozoa. No PAF activity was associated with the seminal fluid. Platelet-activating factor content of spermatozoa may be related to its fertility potential.
authors.affiliation: Department of Obstetrics and Gynecology, East Tennessee State University, James H. Quillen College of Medicine, Johnson City 37614.
authors.forename: B S
authors.initials: BS
authors.lastname: Minhas
authors.forename: R
authors.initials: R
authors.lastname: Kumar
authors.forename: D D
authors.initials: DD
authors.lastname: Ricker
authors.forename: J L
authors.initials: JL
authors.lastname: Robertson
authors.forename: M G
authors.initials: MG
authors.lastname: Dodson
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000187:drug effects / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D006801:Humans; D008055:Lipids / Q000302:isolation & purification; D008297:Male; D010743:Phospholipids / Q000302:isolation & purification*; D010972:Platelet Activating Factor / Q000032:analysis* / Q000494:pharmacology; D011817:Rabbits; D012701:Serotonin / Q000097:blood; D013081:Sperm Motility; D013094:Spermatozoa / Q000737:chemistry* / Q000502:physiology
chemical_list: D008055:Lipids; D010743:Phospholipids; D010972:Platelet Activating Factor; D012701:Serotonin