title: Risk factors for cardiac operations in adult Jehovah's Witnesses.
abstract: During a 27-year-period, 663 adults of the Jehovah's Witness faith underwent open heart procedures at the Texas Heart Institute. To determine the effect of recent changes in operative techniques and in the patient population itself on early mortality, we reevaluated the surgical outcome in this special group of patients. We reviewed the charts of 88 consecutive Jehovah's Witness patients who had an open heart operation between January 1986 and March 1989 and compared demographic variables in this group with those of 575 patients who underwent operation between May 1963 and January 1986. In our recent series, patients were older (mean age, 61 years versus 54 years), and 16% were seen for repeat procedures. Early mortality (less than or equal to 30 days postoperatively) was lower in the recent series than in the earlier series (7.0% versus 10.7%), but the difference between the groups was not statistically significant. We identified several important factors associated with an increased risk of early death in the recent group of patients. These factors included repeat cardiac operations (p less than 0.01), especially for valvar dysfunction, severe left ventricular dysfunction (defined as an ejection fraction less than 0.35) (p less than 0.01), and a hemoglobin level lower than 80 g/L (8 g/dL) (p less than 0.01) on postoperative day 1. Although blood loss remains the leading cause of death in these patients, cardiac operations can be performed with an acceptable mortality.
authors.affiliation: Department of Cardiovascular Surgery, Texas Heart Institute, St. Luke's Episcopal Hospital, Houston 77225-0345.
authors.forename: C T
authors.initials: CT
authors.lastname: Lewis
authors.forename: M C
authors.initials: MC
authors.lastname: Murphy
authors.forename: D A
authors.initials: DA
authors.lastname: Cooley
mesh_terms: D000368:Aged; D006348:Cardiac Surgical Procedures / Q000401:mortality*; D002423:Cause of Death; D002835:Christianity; D005112:Extracorporeal Circulation; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D012086:Reoperation; D012189:Retrospective Studies; D012307:Risk Factors; D013318:Stroke Volume / Q000502:physiology; D015996:Survival Rate; D013781:Texas
chemical_list: D006454:Hemoglobins