title: Implantation of tumor xenografts in nude mice: an improved methodology.
abstract: Xenografting of neoplasms is a common technique in cancer research. Implantation of non-uniform tumor tissue fragments often yields tumor nodules of irregular size and shape, which is disadvantageous. We therefore developed a device to standardize size and shape of such implants. This instrument is effective, inexpensive to fabricate, and simple to use.
authors.affiliation: Department of Surgery, St. Louis University Medical Center, Missouri 63110-0250.
authors.forename: C A
authors.initials: CA
authors.lastname: Hudd
authors.forename: M C
authors.initials: MC
authors.lastname: La Regina
authors.forename: K C
authors.initials: KC
authors.lastname: Tolman
authors.forename: F E
authors.initials: FE
authors.lastname: Johnson
mesh_terms: D000818:Animals; D004867:Equipment Design; D008297:Male; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation / Q000379:methods*; D011786:Quality Control; D014183:Transplantation, Heterologous