title: Carotid bifurcation reconstruction using y-shaped microvascular grafts: an experimental study in rats.
abstract: Reconstruction of the carotid bifurcation was performed in rats using y-shaped microvascular grafts in an attempt to examine the feasibility of using such grafts in intracranial vascular reconstruction, especially for vessels with bifurcations. Twenty y-shaped microarterial grafts were obtained from the carotid bifurcation of donor rats, while 20 y-shaped microvenous grafts were obtained from the femoral veins of the rats. The patency rate of arterial grafts and venous grafts were 75% and 97%, respectively. Anastomotic aneurysms frequently occurred in both arterial grafts (45%) and venous grafts (60%). Results of histological examinations concluded that these aneurysms were false aneurysms. We discuss the reasons for aneurysm formation and technical issues that might improve the experimental results with regard to patency and aneurysm formation.
authors.affiliation: Laboratory of Microsurgery, University of Zurich, Switzerland.
authors.forename: T
authors.initials: T
authors.lastname: Morimoto
authors.forename: H G
authors.initials: HG
authors.lastname: Imhof
authors.forename: O D
authors.initials: OD
authors.lastname: Wiestler
mesh_terms: D000714:Anastomosis, Surgical / Q000379:methods; D000783:Aneurysm / Q000209:etiology; D000818:Animals; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery* / Q000637:transplantation; D005260:Female; D005268:Femoral Vein / Q000637:transplantation; D008297:Male; D008722:Methods; D008866:Microsurgery / Q000379:methods; D011183:Postoperative Complications; D011859:Radiography; D051381:Rats; D011919:Rats, Inbred Strains; D014654:Vascular Patency