title: Adamantane as a brain-directed drug carrier for poorly absorbed drug: antinociceptive effects of [D-Ala2]Leu-enkephalin derivatives conjugated with the 1-adamantane moiety.
authors.affiliation: Teikoku Seiyaku Co., Ltd., Kagawa, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Tsuzuki
authors.forename: T
authors.initials: T
authors.lastname: Hama
authors.forename: T
authors.initials: T
authors.lastname: Hibi
authors.forename: R
authors.initials: R
authors.lastname: Konishi
authors.forename: S
authors.initials: S
authors.lastname: Futaki
authors.forename: K
authors.initials: K
authors.lastname: Kitagawa
mesh_terms: D000218:Adamantane / Q000008:administration & dosage*; D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D001812:Blood-Brain Barrier; D001921:Brain / Q000378:metabolism; D004337:Drug Carriers; D004743:Enkephalin, Leucine / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology*; D008297:Male; D051379:Mice; D012995:Solubility
chemical_list: D000700:Analgesics; D004337:Drug Carriers; D004743:Enkephalin, Leucine; D000218:Adamantane