Aluminium deposition in bone after contamination of drinking water supply.
Two healthy individuals who drank water accidentally contaminated at source with aluminium sulphate solution were investigated 6-7 months later. Bone biopsy specimens showed discrete lines of positive staining for aluminium, the distribution being compatible with acute exposure some months previously. These findings show that under certain conditions normal individuals can absorb aluminium via the gut, and that such aluminium can be deposited in bone.
Eastwood
J B
JB
Department of Cellular and Molecular Sciences, St George's Hospital Medical School, London, UK.
Levin
G E
GE
Pazianas
M
M
Taylor
A P
AP
Denton
J
J
Freemont
A J
AJ
D000328:Adult; D000534:Alum Compounds / Q000032:analysis / Q000378:metabolism / Q000506:poisoning*; D000535:Aluminum / Q000506:poisoning*; D001842:Bone and Bones / Q000032:analysis / Q000378:metabolism*; D004064:Digestive System / Q000378:metabolism; D004326:Drinking; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D007085:Ilium / Q000032:analysis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000139:chemically induced; D009668:Nose Diseases / Q000139:chemically induced; D013997:Time Factors; D014456:Ulcer / Q000139:chemically induced; D014873:Water Pollutants / Q000032:analysis / Q000378:metabolism / Q000506:poisoning*; D014881:Water Supply / Q000032:analysis*
D000534:Alum Compounds; D014873:Water Pollutants; C041524:aluminum sulfate; D000535:Aluminum