title: Two cases of a renal epithelial tumour resembling immature nephron.
abstract: Two cases of renal epithelial tumours are reported in females aged 46 and 66 years respectively. In spite of the large size of the tumours, neither invasive growth nor metastasis was observed. Histologically, the tumours were composed of immature epithelial cells forming tubules with abortive glomeruloid structures. Electron microscopy of tumour cells revealed poorly developed polarity and intracytoplasmic organelles. They showed similar immunohistochemical reactions to those of developing nephrons, particularly to those of the S-shaped body. The nuclear DNA content of the tumour cells was almost euploid. We conclude that the lesions were epithelial tumours of the kidney histologically mimicking developing renal parenchyma.
authors.affiliation: Department of Pathology, Yokohama City University School of Medicine, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Nagashima
authors.forename: N
authors.initials: N
authors.lastname: Arai
authors.forename: Y
authors.initials: Y
authors.lastname: Tanaka
authors.forename: S
authors.initials: S
authors.lastname: Yoshida
authors.forename: K
authors.initials: K
authors.lastname: Sumino
authors.forename: Y
authors.initials: Y
authors.lastname: Ohaki
authors.forename: K
authors.initials: K
authors.lastname: Matsushita
authors.forename: T
authors.initials: T
authors.lastname: Morita
authors.forename: K
authors.initials: K
authors.lastname: Misugi
mesh_terms: D000368:Aged; D002277:Carcinoma / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D037102:Lectins; D008854:Microscopy, Electron; D008875:Middle Aged; D009399:Nephrons / Q000033:anatomy & histology* / Q000254:growth & development / Q000378:metabolism
chemical_list: D037102:Lectins