[The effect of stimulation of the beta-adrenoreceptors on ion and water transport in the distal kidney tubule of the triton].
The ion and fluid reabsorption during perfusion of inter-tubular capillaries with different subtypes of beta-adrenergic agonists was studied in the newt distal tubule using the micropuncture technique and X-ray microanalysis. Isoproterenol (10(-5) M) did not affect the ion and water transport. Stimulation of beta 1-adrenergic receptor with isoproterenol and beta 2-adrenergic antagonist ICI 118.551 inhibited the fractional reabsorption of sodium, chloride and magnesium, the fluid reabsorption being changed insignificantly. Stimulation of beta 2-adrenergic receptor with ventolin increased the fractional calcium reabsorption. The transport of water and other ions did not change.
Goncharevskaia
O A
OA
Monin
Iu G
IuG
D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000420:Albuterol / Q000494:pharmacology; D000818:Animals; D001692:Biological Transport / Q000187:drug effects / Q000502:physiology; D004573:Electrolytes / Q000378:metabolism*; D007545:Isoproterenol / Q000494:pharmacology; D007686:Kidney Tubules, Distal / Q000187:drug effects* / Q000502:physiology; D011412:Propanolamines / Q000494:pharmacology; D011943:Receptors, Adrenergic, beta / Q000187:drug effects* / Q000502:physiology; D013268:Stimulation, Chemical; D014319:Triturus / Q000502:physiology*; D014867:Water / Q000378:metabolism*
D000319:Adrenergic beta-Antagonists; D004573:Electrolytes; D011412:Propanolamines; D011943:Receptors, Adrenergic, beta; D014867:Water; C026777:ICI 118551; D007545:Isoproterenol; D000420:Albuterol