[Results of a survey on the use of delayed-action neuroleptics in psychiatry].
Depot neuroleptics have been empirically used for 30 years by psychiatrists. An inquiry was performed among private and public psychiatrists. The goal of the study was to understand the prescription rules of depot neuroleptics. A questionnaire was systematically sent to all psychiatrists working in Loire-Atlantique. The answer rate was 41.4% which is quite good for this kind of inquiry. The main indications of depot neuroleptics were chronic deliria and schizophrenia. Dosages are not accorded to negative or productive symptoms. Therapists do not think that there are efficacy differences between marketed drugs. Few of them use therapeutic windows. Prescriptions were not adjusted following drug pharmacokinetic parameters. So this work lays down rules about rational prescriptions and drug monitoring of depot neuroleptic concentrations.
Bourin
M
M
Département de Pharmacologie Clinique, C.H.U., Nantes.
Venisse
J L
JL
Lecuyer
F
F
D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003692:Delayed-Action Preparations; D004363:Drug Utilization; D005602:France; D006761:Hospitals; D006801:Humans; D001523:Mental Disorders / Q000188:drug therapy*; D011331:Private Practice; D011795:Surveys and Questionnaires
D014150:Antipsychotic Agents; D003692:Delayed-Action Preparations