title: Bioconcentration and excretion of diazinon, IBP, malathion and fenitrothion by carp.
abstract: 1. Bioconcentration and excretion of diazinon, IBP, malathion and fenitrothion were studied for carp (Cyprinus carpio L.). 2. The concentrations of these pesticides in muscle and viscera of the carp reached plateaus in 12-48 hr exposure. 3. The average values of bioconcentration factors (BCF) for diazinon were 20.9 in muscle, 60.0 in liver, 111.1 in kidney and 32.2 in gallbladder over the 168 hr exposure period. Similarly, those values were 4.3-26.7 for IBP, 2.7-17.3 for malathion, and 36.0-157.1 for fenitrothion. 4. The excretion rate constants of malathion (hr-1) were 0.13 for muscle, 0.12 for liver, 0.08 for kidney and 0.06 for gallbladder. Those of diazinon, IBP and fenitrothion (g.ng-1.hr-1) were 0.002-0.024 for muscle, 0.001-0.020 for liver, 0.0004-0.004 for kidney and 0.002-0.023 for gallbladder, respectively.
authors.affiliation: Shiga Prefectural Institute of Public Health and Environmental Science, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Tsuda
authors.forename: S
authors.initials: S
authors.lastname: Aoki
authors.forename: M
authors.initials: M
authors.lastname: Kojima
authors.forename: H
authors.initials: H
authors.lastname: Harada
mesh_terms: D000818:Animals; D002347:Carps / Q000378:metabolism*; D003976:Diazinon / Q000493:pharmacokinetics*; D005278:Fenitrothion / Q000493:pharmacokinetics*; D005659:Fungicides, Industrial / Q000493:pharmacokinetics; D005704:Gallbladder / Q000378:metabolism; D007306:Insecticides / Q000493:pharmacokinetics; D007668:Kidney / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D008294:Malathion / Q000493:pharmacokinetics*; D009132:Muscles / Q000378:metabolism; D009946:Organothiophosphorus Compounds / Q000493:pharmacokinetics*; D010575:Pesticides / Q000493:pharmacokinetics*
chemical_list: D005659:Fungicides, Industrial; D007306:Insecticides; D009946:Organothiophosphorus Compounds; D010575:Pesticides; C009897:O,O-diisopropyl-S-benzylthiophosphate; D008294:Malathion; D005278:Fenitrothion; D003976:Diazinon