Influences of structural factors of biological media on the acoustic nonlinearity parameter B/A.
The influence of structural factors of biological media on the acoustic nonlinearity parameter B/A have been studied at the tissue, cellular, and molecular levels, using the thermodynamic and finite amplitude methods. B/A was determined as the structural factors of the media were altered physically and biochemically, while chemical composition was maintained unchanged. Significant structural dependencies of B/A were observed at all three levels; 26% of the dry weight contribution to the total B/A (the B/A value with water contribution subtracted) is due to the cell-cell adhesive force in liver tissue, 20% is due to the hepatocyte cellular structure, and 15% is due to secondary and tertiary protein structure.
Zhang
J
J
Department of Electrical and Computer Engineering, University of Illinois, Urbana-Champaign 61801.
Kuhlenschmidt
M S
MS
Dunn
F
F
D000162:Acoustics; D000818:Animals; D002415:Cats; D002448:Cell Adhesion / Q000502:physiology; D008099:Liver / Q000166:cytology*; D008954:Models, Biological; D008962:Models, Theoretical; D011487:Protein Conformation; D051381:Rats; D011919:Rats, Inbred Strains; D012815:Signal Processing, Computer-Assisted; D013816:Thermodynamics; D014465:Ultrasonics