Age-associated alterations in diazepam metabolizing enzyme activities in male and female rats.
Fujita
S
S
Department of Toxicology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Tatsuno
J
J
Kitani
K
K
Suzuki
T
T
D000375:Aging / Q000378:metabolism*; D000818:Animals; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D003640:Dealkylation; D003975:Diazepam / Q000378:metabolism*; D005260:Female; D006900:Hydroxylation; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology*; D010089:Oxidoreductases, N-Demethylating / Q000378:metabolism; D051381:Rats; D011916:Rats, Inbred F344; D012737:Sex Factors
D003577:Cytochrome P-450 Enzyme System; D010089:Oxidoreductases, N-Demethylating; C067539:diazepam N-demethylase; D003975:Diazepam