title: Sick building syndrome.
abstract: "Sick building syndrome" (SBS) is one of the more colorful terms describing an increasingly common pattern of symptoms found among workers in modern office buildings. Core symptoms include lethargy, mucous membrane irritation, headache, eye irritation, and dry skin. To prompt a diagnosis of SBS, these otherwise common symptoms must be "excessively" reported and primarily "work-related." The World Health Organization now estimates that 30% of new or remodeled office buildings show signs of SBS, and that between 10% and 30% of the occupants of these buildings are affected by SBS. Despite such figures, SBS remains poorly researched and even more poorly understood. The following review provides the clinician an overview of SBS that will allow a more accurate differential diagnosis and will help to prevent the widespread suffering that can accrue when SBS is not quickly recognized.
authors.affiliation: Department of Psychiatry, College of Medicine, College of Health Related Professions, University of Florida, Gainesville 32610.
authors.forename: W B
authors.initials: WB
authors.lastname: Lyles
authors.forename: K W
authors.initials: KW
authors.lastname: Greve
authors.forename: R M
authors.initials: RM
authors.lastname: Bauer
authors.forename: M R
authors.initials: MR
authors.lastname: Ware
authors.forename: C J
authors.initials: CJ
authors.lastname: Schramke
authors.forename: J
authors.initials: J
authors.lastname: Crouch
authors.forename: A
authors.initials: A
authors.lastname: Hicks
mesh_terms: D000389:Air Conditioning / Q000009:adverse effects; D000393:Air Pollutants / Q000009:adverse effects; D003937:Diagnosis, Differential; D004781:Environmental Exposure / Q000009:adverse effects* / Q000517:prevention & control; D005128:Eye Diseases / Q000175:diagnosis / Q000209:etiology*; D005160:Facility Design and Construction / Q000592:standards; D006261:Headache / Q000175:diagnosis / Q000209:etiology*; D006749:Hospital Design and Construction / Q000592:standards; D006801:Humans; D007753:Laboratories / Q000592:standards; D010608:Pharyngeal Diseases / Q000175:diagnosis / Q000209:etiology*; D012871:Skin Diseases / Q000175:diagnosis / Q000209:etiology*; D012894:Sleep Stages / Q000502:physiology*; D014691:Ventilation / Q000592:standards
chemical_list: D000393:Air Pollutants