Autonomic control of heart rate in the adult, aquatic Notophthalmus viridescens viridescens.
1. We investigated the role of the autonomic nervous system in the control of the heart rate using an isolated heart preparation. 2. Addition of the parasympathetic blocker, atropine, to the organ bath resulted in an increase in heart rate as expected. 3. Addition of the sympathetic blocker, ergotamine, to the organ bath showed no change in the heart rate. 4. Addition of the sympathetic blocker, propranolol, to the organ bath resulted in the expected decrease in heart rate. 5. Both the sympathetic and parasympathetic nervous systems appear to play a role in the control of the heart rate.
Pitkin
R B
RB
Biology Department, Allegheny College, Meadville, PA 16335.
Bonnet
K M
KM
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D004878:Ergotamine / Q000494:pharmacology; D006339:Heart Rate / Q000187:drug effects; D009673:Notophthalmus viridescens / Q000502:physiology*; D010275:Parasympathetic Nervous System / Q000502:physiology*; D011433:Propranolol / Q000494:pharmacology; D013564:Sympathetic Nervous System / Q000502:physiology*
D001285:Atropine; D011433:Propranolol; D004878:Ergotamine