title: Prediction of response to electroconvulsive therapy. Preliminary validation of a sign-based typology of depression.
abstract: In an open study of 35 depressed patients, psychomotor disturbance, assessed by the CORE rating system, significantly predicted response to ECT in patients with a 'retarded' but not those with an 'agitated' type of illness. In multivariate analyses, psychomotor disturbance was the sole predictor of response. This preliminary study suggests that the CORE system, which has been shown to differentiate endogenous and non-endogenous depressive disorders, has predictive validity in relation to ECT response.
authors.affiliation: Division of Psychiatry, Prince Henry Hospital, Sydney, Australia.
authors.forename: I
authors.initials: I
authors.lastname: Hickie
authors.forename: B
authors.initials: B
authors.lastname: Parsonage
authors.forename: G
authors.initials: G
authors.lastname: Parker
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000928:Antidepressive Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003866:Depressive Disorder / Q000145:classification / Q000523:psychology / Q000628:therapy*; D004565:Electroconvulsive Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011569:Psychiatric Status Rating Scales
chemical_list: D000928:Antidepressive Agents; D014150:Antipsychotic Agents