The source of avian paramyxoviruses isolated during an outbreak of influenza among children.
In 1986 five avian paramyxovirus (PMV) strains were isolated in embryonated chicken eggs from sick children with influenza. The strains were identified as PMV-2 serotype due to the close antigenic relationships between their HN-proteins and of the reference PMV-2 strains isolated from different birds all over the world. No seroconversion to the isolates was found in the sick children, however, HI-antibodies were detected in hen's sera, eggs of which were used for the new strains isolation. The possible origin of isolated PMV-2 viruses is discussed.
Yakhno
M A
MA
D. I. Ivanovsky Institute of Virology, Academy of Medical Sciences of U.S.S.R., Prague, Czechoslovakia.
Govorkova
E A
EA
Kubínova
I
I
Ivanova
V T
VT
Stumpa
A
A
Tůmová
B
B
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D000956:Antigens, Viral / Q000276:immunology; D001717:Birds / Q000382:microbiology*; D002642:Chick Embryo; D002648:Child; D003604:Czechoslovakia / Q000453:epidemiology; D004196:Disease Outbreaks; D015707:HN Protein / Q000032:analysis; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D005779:Immunodiffusion; D007251:Influenza, Human / Q000276:immunology / Q000382:microbiology*; D010252:Paramyxoviridae / Q000302:isolation & purification*
D000914:Antibodies, Viral; D000956:Antigens, Viral; D015707:HN Protein