CGS 18102A, a benzopyranopyridine anxiolytic with 5-HT1 agonist and 5-HT2 antagonist properties.
Sills
M A
MA
Research Department, CIBA-GEIGY Corporation, Summit, NJ 07901.
Bennett
D A
DA
Lovell
R A
RA
Liebman
J M
JM
Wood
P L
PL
Glaeser
B S
BS
Williams
M
M
Hutchison
A J
AJ
D017371:8-Hydroxy-2-(di-n-propylamino)tetralin; D000818:Animals; D014151:Anti-Anxiety Agents / Q000494:pharmacology; D001578:Benzopyrans / Q000494:pharmacology*; D001667:Binding, Competitive; D002540:Cerebral Cortex / Q000378:metabolism; D007650:Ketanserin / Q000037:antagonists & inhibitors / Q000378:metabolism; D007700:Kinetics; D010880:Piperidines / Q000494:pharmacology*; D051381:Rats; D011985:Receptors, Serotonin / Q000378:metabolism; D012701:Serotonin / Q000378:metabolism / Q000502:physiology; D012702:Serotonin Antagonists / Q000378:metabolism / Q000494:pharmacology*; D013764:Tetrahydronaphthalenes / Q000037:antagonists & inhibitors / Q000378:metabolism
D014151:Anti-Anxiety Agents; D001578:Benzopyrans; D010880:Piperidines; D011985:Receptors, Serotonin; D012702:Serotonin Antagonists; D013764:Tetrahydronaphthalenes; C067554:CGS 18102A; D012701:Serotonin; D017371:8-Hydroxy-2-(di-n-propylamino)tetralin; D007650:Ketanserin