Evidence against extended DR3-related haplotypes in Graves' disease.
Three HLA-DR3-linked polymorphisms of the DPA, DPB and DRB genes, previously associated with myasthenia gravis or coeliac disease, have been examined in Caucasian patients with Graves' disease. The patients did not differ from healthy DR3 subjects, indicating an absence of any association of Graves' disease with specific DR3 subtypes.
Weetman
A P
AP
Department of Medicine, University of Cambridge Clinical School, Addenbrooke's Hospital, U.K.
McCorkle
R
R
D006111:Graves Disease / Q000235:genetics / Q000276:immunology*; D006682:HLA-DP Antigens / Q000235:genetics; D006683:HLA-DQ Antigens / Q000235:genetics; D015803:HLA-DR3 Antigen / Q000235:genetics*; D006239:Haplotypes; D006801:Humans; D007125:Immunogenetics; D012150:Polymorphism, Restriction Fragment Length
D006682:HLA-DP Antigens; D006683:HLA-DQ Antigens; D015803:HLA-DR3 Antigen