title: Error-prone SOS repair can be error-free.
abstract: Most of the mutagenesis that accompanies the SOS repair of ultraviolet light-induced lesions in the single-stranded DNA of phage S13 is eliminated when the groES or the groEL gene of Escherichia coli is defective. Therefore, this SOS mutagenesis is not a necessary consequence of what is commonly called error-prone repair, but is additionally imposed on the repair system by the GroE heat shock proteins, which are responsible for the assembly of polypeptides into multimeric structures.
authors.affiliation: Department of Biological Sciences, Purdue University, West Lafayette, IN 47907.
authors.forename: S K
authors.initials: SK
authors.lastname: Liu
authors.forename: I
authors.initials: I
authors.lastname: Tessman
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics*; D018835:Chaperonin 10; D018834:Chaperonin 60; D004926:Escherichia coli / Q000235:genetics*; D006360:Heat-Shock Proteins / Q000235:genetics* / Q000502:physiology*; D016296:Mutagenesis / Q000528:radiation effects*; D013014:SOS Response, Genetics; D014466:Ultraviolet Rays
chemical_list: D001426:Bacterial Proteins; D018835:Chaperonin 10; D018834:Chaperonin 60; D006360:Heat-Shock Proteins