Propofol for induction and maintenance of anaesthesia at caesarean section. A comparison with thiopentone/enflurane.
A propofol infusion regimen and a standard general anaesthetic were compared in 40 Chinese women undergoing elective Caesarean section. Twenty patients received propofol 2 mg/kg for induction of anaesthesia followed by propofol 6 mg/kg/hour, while 20 patients received thiopentone 4 mg/kg with enflurane 1% for maintenance of anaesthesia. All patients were given atracurium and their lungs ventilated with nitrous oxide 50% in oxygen until delivery of the neonate. The hypertensive response after intubation was of shorter duration in the propofol group compared with the thiopentone group. Induction to delivery times ranged from 5 to 14 minutes and neonates from both groups had similar and satisfactory Apgar scores. Neurologic and Adaptive Capacity Scores and umbilical cord blood gas analysis. However, a prolonged propofol infusion time before delivery may cause lower Neurologic and Adaptive Capacity Scores. There were no differences in maternal recovery times or psychomotor performance.
Yau
G
G
Department of Anaesthesia and Intensive Care, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin.
Gin
T
T
Ewart
M C
MC
Kotur
C F
CF
Leung
R K
RK
Oh
T E
TE
D000328:Adult; D000762:Anesthesia Recovery Period; D000769:Anesthesia, Inhalation; D000771:Anesthesia, Intravenous; D000773:Anesthesia, Obstetrical; D001034:Apgar Score; D002585:Cesarean Section; D004737:Enflurane / Q000494:pharmacology; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D015742:Propofol / Q000494:pharmacology; D013874:Thiopental / Q000494:pharmacology
D004737:Enflurane; D013874:Thiopental; D015742:Propofol