title: Zinc sulfide in intestinal cell granules of Ancylostoma caninum adults.
abstract: A source of confusion has existed since the turn of the century about the reddish brown, weakly birefringent "sphaerocrystals" located in the intestines of strongyle nematodes, Strongylus and Ancylostoma. X-ray diffraction and energy dispersive spectrometric analyses were used for accurate determination of the crystalline order and elemental composition of the granules in the canine hookworm Ancylostoma caninum. The composition of the intestinal pigmented granules was identified unequivocally as zinc sulfide. It seems most probable that the granules serve to detoxify high levels of metallic ions (specifically zinc) present due to the large intake of host blood.
authors.affiliation: Department of Biology, Portland State University, Oregon 97207.
authors.forename: A J
authors.initials: AJ
authors.lastname: Gianotti
authors.forename: D T
authors.initials: DT
authors.lastname: Clark
authors.forename: J
authors.initials: J
authors.lastname: Dash
mesh_terms: D000722:Ancylostoma / Q000032:analysis* / Q000648:ultrastructure; D000818:Animals; D003460:Crystallization; D003594:Cytoplasmic Granules / Q000737:chemistry* / Q000648:ultrastructure; D004577:Electron Probe Microanalysis; D007422:Intestines / Q000737:chemistry; D008855:Microscopy, Electron, Scanning; D013440:Sulfides / Q000032:analysis*; D014961:X-Ray Diffraction; D015032:Zinc / Q000032:analysis*; D017967:Zinc Compounds
chemical_list: D013440:Sulfides; D017967:Zinc Compounds; D015032:Zinc; C031238:zinc sulfide