title: Lack of induced increase in sister chromatid exchanges in human lymphocytes exposed to in vivo therapeutic ultrasound.
abstract: In 1984 Stella et al. reported that each of 10 patients exposed to therapeutic ultrasound had a statistically significant increase in sister chromatid exchanges (SCEs) at mid- and end of therapy; there was a wide range of clinical symptoms (e.g., elbow epicondylitis to knee arthrosis) in this set of patients. In the present study, a set of 4 patients each with some diagnosis recommending therapeutic ultrasound was similarly tested for SCE induction; an additional set of 4 healthy persons underwent sham-therapeutic ultrasound exposures. For both sets of subjects (patients, nonpatients) there was no increase in the frequency of SCEs.
authors.affiliation: Department of Biophysics, School of Medicine and Dentistry, University of Rochester, NY 14642.
authors.forename: M W
authors.initials: MW
authors.lastname: Miller
authors.forename: M
authors.initials: M
authors.lastname: Azadniv
authors.forename: C
authors.initials: C
authors.lastname: Cox
authors.forename: W M
authors.initials: WM
authors.lastname: Miller
mesh_terms: D000328:Adult; D002062:Bursitis / Q000097:blood / Q000628:therapy; D006801:Humans; D008214:Lymphocytes; D008875:Middle Aged; D012854:Sister Chromatid Exchange; D014464:Ultrasonic Therapy