title: Cystic fibrosis: MR imaging of the pancreas.
abstract: The appearance of the pancreas in 17 adult patients with cystic fibrosis was evaluated with magnetic resonance (MR) imaging. The pancreas was abnormal in 15 patients. Three patterns were observed: (a) lobulated enlarged pancreas with complete replacement by fatty tissue (n = 9), (b) small atrophic pancreas with partial replacement by fat tissue (n = 5), and (c) diffuse atrophy of the pancreas without fatty replacement (n = 1). Replacement of the pancreas by fat tissue was seen on T1-weighted images with, characteristically, a very high signal intensity. The sensitivity of MR imaging in depicting pancreatic abnormality in cystic fibrosis is 94%, which is comparable to that of computed tomography.
authors.affiliation: Department of Diagnostic Radiology, University Medical Centre Leiden, Eindhoven, The Netherlands.
authors.forename: R T
authors.initials: RT
authors.lastname: Tham
authors.forename: H G
authors.initials: HG
authors.lastname: Heyerman
authors.forename: T H
authors.initials: TH
authors.lastname: Falke
authors.forename: A H
authors.initials: AH
authors.lastname: Zwinderman
authors.forename: J L
authors.initials: JL
authors.lastname: Bloem
authors.forename: W
authors.initials: W
authors.lastname: Bakker
authors.forename: C B
authors.initials: CB
authors.lastname: Lamers
mesh_terms: D000293:Adolescent; D000328:Adult; D003550:Cystic Fibrosis / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010179:Pancreas / Q000473:pathology*