Isolation and chromosomal localization of a novel FMS-like tyrosine kinase gene.
We have isolated and sequenced part of a new gene of the tyrosine kinase family. This gene, called FLT3, has strong sequence similarities with members of a group of genes encoding growth factor receptors: FMS, KIT, and PDGFR. We have localized the human FLT3 gene to chromosome 13, band q12, and its mouse homolog to chromosome 5, region G.
Rosnet
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U.119 INSERM, Marseille, France.
Matteï
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MG
Marchetto
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Birnbaum
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D
D000595:Amino Acid Sequence; D000818:Animals; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002882:Chromosomes, Human, Pair 13; D066246:ErbB Receptors / Q000235:genetics; D016236:Genes, fms; D006801:Humans; D008297:Male; D051379:Mice; D008969:Molecular Sequence Data; D005810:Multigene Family; D011505:Protein-Tyrosine Kinases / Q000235:genetics* / Q000378:metabolism; D012689:Sequence Homology, Nucleic Acid; D013737:Testis / Q000201:enzymology
D066246:ErbB Receptors; D011505:Protein-Tyrosine Kinases