A new enzymatic method gives F(ab)2 suitable for 99mTc labeling and use in immunoscintigraphy.
Seccamani
E
E
Sorin Biomedica, Saluggia, VC, Italy.
Tarditi
L
L
Bonino
C
C
Camagna
M
M
Moscatelli
G
G
Mariani
M
M
Riva
P
P
D000818:Animals; D002272:Carcinoembryonic Antigen / Q000276:immunology; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000302:isolation & purification* / Q000493:pharmacokinetics; D007553:Isotope Labeling; D009369:Neoplasms / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D051381:Rats; D013667:Technetium; D014018:Tissue Distribution
D002272:Carcinoembryonic Antigen; D007140:Immunoglobulin Fab Fragments; D013667:Technetium