Therapeutic approaches affecting diastolic ventricular function.
The therapeutic approaches affecting diastolic ventricular function are conditional on underlying physiology, especially as it relates to calcium cycling, early relaxation and rapid filling abnormalities, atrial function, hemodynamics, the presence of hypertrophy, and neurohormonal milieu. A wide variety of treatment considerations are discussed, with particular attention to the management of cardiomyopathy characterized by pure or predominant diastolic failure (Table 1).
Warren
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SE
Charles A. Dana Research Institute, Beth Israel Hospital, Boston, Massachusetts.
Grossman
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W
D002317:Cardiovascular Agents / Q000627:therapeutic use*; D003971:Diastole / Q000187:drug effects* / Q000502:physiology; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D016277:Ventricular Function, Left / Q000187:drug effects* / Q000502:physiology
D002317:Cardiovascular Agents