Early development of rubrospinal and cerebellorubral projections in Xenopus laevis.
In Xenopus laevis HRP was applied at the spinomedullary border at various stages of development. In these experiments labeled rubrospinal neurons were observed from stage 48 on. HRP applications to the mesencephalic tegmentum showed, from stage 49 on, retrogradely labeled neurons in the cerebellar nucleus, particularly contralaterally. These data suggest that anuran cerebellorubral projections arise early, well before the rubrospinal innervation of the spinal cord is complete.
ten Donkelaar
H J
HJ
Department of Anatomy and Embryology, University of Nijmegen, The Netherlands.
de Boer-van Huizen
R
R
van der Linden
J A
JA
D000818:Animals; D002531:Cerebellum / Q000502:physiology*; D006735:Horseradish Peroxidase; D007814:Larva; D012012:Red Nucleus / Q000502:physiology*; D013116:Spinal Cord / Q000502:physiology*; D013681:Tegmentum Mesencephali / Q000502:physiology; D014982:Xenopus laevis / Q000254:growth & development* / Q000502:physiology
D006735:Horseradish Peroxidase