Medication induced esophageal injury.
Five patients of medication-induced esophageal injury are reported. A history of ingestion of medications preceding the onset of dysphagia was obtained in all patients. Endoscopy revealed localised mucosal ulceration with surrounding edematous mucosa at the level of the aortic arch in four, and in the retro-cardiac esophagus in one patient. The medications involved were sustained release potassium chloride, doxycycline, ibuprofen, and an unidentified antibiotic and antihypertensive (one each). Healing of the esophageal ulcers was confirmed in all the patients by endoscopy.
Mohandas
K M
KM
Department of Medical Gastroenterology, Tata Memorial Hospital, Parel, Bombay.
Swaroop
V S
VS
Desai
D C
DC
Dhir
V
V
Nagral
A
A
Desai
P B
PB
Vyas
J J
JJ
D000293:Adolescent; D000328:Adult; D000368:Aged; D004318:Doxycycline / Q000009:adverse effects*; D004935:Esophageal Diseases / Q000139:chemically induced*; D006801:Humans; D007052:Ibuprofen / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011189:Potassium Chloride / Q000009:adverse effects*
D011189:Potassium Chloride; D004318:Doxycycline; D007052:Ibuprofen