Ifosfamide-induced Fanconi's syndrome with growth failure in a 2-year-old child.
Fanconi's syndrome with phosphopenic rickets is described in a 2-year-old girl who had been treated for an embryonal sarcoma with multiagent chemotherapy including high-dose ifosfamide. The radiological and biochemical signs of rickets disappeared after treatment with 25-OH vitamin D3 and phosphorus supplements. Monitoring of tubular function in children during and after treatment with ifosfamide is mandatory.
De Schepper
J
J
Departments of Pediatrics, V.U.B., Belgium.
Stevens
G
G
Verboven
M
M
Baeta
C
C
Otten
J
J
D002675:Child, Preschool; D005198:Fanconi Syndrome / Q000139:chemically induced* / Q000150:complications / Q000652:urine; D005260:Female; D006130:Growth Disorders / Q000139:chemically induced* / Q000209:etiology; D006801:Humans; D007069:Ifosfamide / Q000009:adverse effects*; D012279:Rickets / Q000139:chemically induced* / Q000150:complications
D007069:Ifosfamide