title: [Chronic rejection of a transplanted heart].
abstract: Three cases of chronic rejection occurring 7.5, 10, and 24 months after transplantation of the heart are analysed. The clinical features of chronic rejection in the late-term periods after transplantation of the heart are discussed. The problems of clinical diagnosis of chronic rejection, the role of endomyocardial biopsy and disorders of lipid metabolism are dealt with. Tactics of saving the patient are recommended. The authors substantiate the necessity for heart retransplantation and, in the absence of a donor's heart, for two-stage transplantation of the heart through an artificial heart or a biventricular approach by means of artificial heart ventricles.
authors.forename: V I
authors.initials: VI
authors.lastname: Shumakov
authors.forename: E N
authors.initials: EN
authors.lastname: Kazakov
authors.forename: A Ia
authors.initials: AIa
authors.lastname: Kormer
authors.forename: A Sh
authors.initials: ASh
authors.lastname: Khubutiia
authors.forename: G M
authors.initials: GM
authors.lastname: Mogilevskiĭ
authors.forename: O A
authors.initials: OA
authors.lastname: Giorgadze
authors.forename: V V
authors.initials: VV
authors.lastname: Chestukhin
authors.forename: A E
authors.initials: AE
authors.lastname: Belova
authors.forename: I V
authors.initials: IV
authors.lastname: Smirnova
mesh_terms: D000328:Adult; D006084:Graft Rejection; D016027:Heart Transplantation; D006801:Humans; D008297:Male; D013997:Time Factors