Nesidioblastosis: evidence for autosomal recessive inheritance.
The risk of recurrence of nesidioblastosis is unclear. Thirty patients from 28 families were studied; the marriages were consanguineous in five families. The ratio of subsequent affected to unaffected siblings was similar to that of an autosomal recessive condition and the sex ratio was close to 1.
Woolf
D A
DA
Institute of Child Health, University of London.
Leonard
J V
JV
Trembath
R C
RC
Pembrey
M E
ME
Grant
D B
DB
D005260:Female; D005808:Genes, Recessive / Q000235:genetics; D006801:Humans; D008297:Male; D010182:Pancreatic Diseases / Q000235:genetics*; D010375:Pedigree