title: Otogenic Fusobacterium necrophorum meningitis.
abstract: A case of meningitis secondary to acute suppurative otitis media in a previously healthy child is reported. The only organism isolated from blood after aerobic and prolonged anaerobic culture was identified as Fusobacterium necrophorum. Complete recovery followed treatment with surgery and prolonged antibiotic therapy. The role of anaerobes in the development of meningitis, the isolation and identification of Fusobacterium necrophorum, the clinical presentations of F. necrophorum infection and the choice of antibiotics in the treatment of these infections are discussed.
authors.affiliation: University Department of Otolaryngology, Manchester Royal Infirmary.
authors.forename: A
authors.initials: A
authors.lastname: Pace-Balzan
authors.forename: A O
authors.initials: AO
authors.lastname: Keith
authors.forename: J W
authors.initials: JW
authors.lastname: Curley
authors.forename: R T
authors.initials: RT
authors.lastname: Ramsden
authors.forename: H
authors.initials: H
authors.lastname: Lewis
mesh_terms: D000208:Acute Disease; D002675:Child, Preschool; D002701:Chloramphenicol / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005674:Fusobacterium Infections / Q000628:therapy; D005675:Fusobacterium necrophorum; D006801:Humans; D008416:Mastoid / Q000601:surgery; D008581:Meningitis / Q000382:microbiology* / Q000628:therapy; D008795:Metronidazole / Q000627:therapeutic use; D010035:Otitis Media, Suppurative / Q000382:microbiology* / Q000628:therapy; D010406:Penicillins / Q000627:therapeutic use
chemical_list: D010406:Penicillins; D008795:Metronidazole; D002701:Chloramphenicol