Optimal arterial blood pressure.
Based on the principle of minimum power, a mathematical model of the functional state of the circulatory system is presented. The optimization model minimizes the power expenditure of the heart, bone marrow and the power expended in carrying blood. Mean arterial blood pressure is determined depending on oxygen transport parameters and locomotor activity. Theoretical results are compared with experimental data for man.
Khanin
M A
MA
Biomedical Cybernetics Research Council, Academy of Medical Sciences of U.S.S.R., Moscow.
Bukharov
I B
IB
D001775:Blood Circulation / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D002320:Cardiovascular Physiological Phenomena; D006400:Hematocrit; D006801:Humans; D008124:Locomotion / Q000502:physiology; D008433:Mathematics; D008954:Models, Biological