title: [The significance of Gd-DTPA-enhanced MR imaging in endometrial carcinomas].
abstract: To evaluate the feasibility of Gd-DTPA-enhanced magnetic resonance (MR) imaging combined with dynamic study in the diagnosis of endometrial carcinomas, we performed MR studies on five healthy volunteers, 17 patients with histologically proved endometrial carcinomas and three patients with atypical hyperplasia of the endometrium. While adenocarcinomas of endometrium were less enhanced than myometrium after Gd-DTPA, clear cell adenocarcinomas became enhanced and isointense to myometrium. The lesions of atypical endometrial hyperplasia were more enhanced than myometrium. Dynamic study using Gd-DTPA offered no further yielding information in those lesions. The results suggest that Gd-DTPA-enhanced MR imaging is an important method in the diagnosis of endometrial carcinomas and differentiation among an adenocarcinoma of the endometrium, a clear cell adenocarcinoma and atypical endometrial hyperplasia.
authors.affiliation: Department of Radiology, Kinki University School of Medicine.
authors.forename: F
authors.initials: F
authors.lastname: Matsumoto
authors.forename: N
authors.initials: N
authors.lastname: Mabuchi
authors.forename: H
authors.initials: H
authors.lastname: Yoshioka
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis*; D000368:Aged; D003287:Contrast Media; D004714:Endometrial Hyperplasia / Q000175:diagnosis*; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid; D014594:Uterine Neoplasms / Q000175:diagnosis*
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA