title: Cosmetic treatment of shagreen patches in selected patients with tuberous sclerosis.
abstract: Patients with mild forms of tuberous sclerosis may request cosmetic treatment of skin hamartomas. Treatment may consist of planning of an elevated shagreen patch with a Reese dermatome and/or laser treatment of facial angiofibromas. These precise patients, i.e., patients with a forme fruste of tuberous sclerosis, are more likely to have pulmonary involvement than patients with the usual complete disease form. A chest x-ray should be obtained in these patients to rule out pulmonary involvement. Half the patients with pulmonary involvement of tuberous sclerosis die an avoidable death from spontaneous pneumothoraces. Positive-pressure ventilation during anesthesia in these patients should be avoided or monitored closely.
authors.affiliation: Department of Surgery, University of California, Irvine.
authors.forename: J R
authors.initials: JR
authors.lastname: Wendt
authors.forename: L R
authors.initials: LR
authors.lastname: Watson
mesh_terms: D000328:Adult; D006801:Humans; D008297:Male; D013518:Surgery, Plastic / Q000379:methods*; D014402:Tuberous Sclerosis / Q000601:surgery*