title: Staphylococcus aureus growth and type 5 capsular polysaccharide production in synthetic media.
abstract: The production of type 5 capsular polysaccharide by Staphylococcus aureus in synthetic media was investigated. The influence of medium components on capsular polysaccharide synthesis appeared to relate to the presence or absence of the component rather than to concentration gradient. The production of type 5 capsular polysaccharide was linked to energy availability and energy source, but not to carbohydrate concentration or carbon/nitrogen ratio. Regulation of capsular polysaccharide production by S. aureus in response to medium changes would appear to differ from that typically displayed in other organisms that produce polysaccharides.
authors.affiliation: Département d'Ecologie, Institut Pasteur, Paris, France.
authors.forename: W T
authors.initials: WT
authors.lastname: Stringfellow
authors.forename: B
authors.initials: B
authors.lastname: Dassy
authors.forename: M
authors.initials: M
authors.lastname: Lieb
authors.forename: J M
authors.initials: JM
authors.lastname: Fournier
mesh_terms: D016667:Bacterial Capsules; D050260:Carbohydrate Metabolism; D003470:Culture Media; D004734:Energy Metabolism; D011135:Polysaccharides, Bacterial / Q000096:biosynthesis*; D013211:Staphylococcus aureus / Q000254:growth & development / Q000378:metabolism*
chemical_list: D003470:Culture Media; D011135:Polysaccharides, Bacterial; C054106:capsular polysaccharide, type 5, Staphylococcus aureus