[Blood levels of medium molecular weight peptides and lipid peroxidation activity in the differential diagnosis of diffuse toxic goiter].
A study was made of the level of medium molecular peptides (MMP) and lipid peroxidation (LRO) activity in 36 patients with Basedow's disease of various degrees of severity and in patients with functional diseases of the nervous system. A statistically significant rise of the blood level of MMP in patients with Basedow's disease was established with relation to a group of healthy persons and patients with functional diseases of the nervous system. Correlations were found between the blood level of MMP, LPO activity and absorption of radioactive iodine by the thyroid. The blood level of MMP should be used as a screening test for clinico-laboratory diagnosis to differentiate between Basedow's disease and functional diseases of the nervous system.
Iangolenko
V V
VV
Okorokov
A N
AN
D000293:Adolescent; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D006111:Graves Disease / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D015227:Lipid Peroxidation / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D008970:Molecular Weight; D009422:Nervous System Diseases / Q000097:blood / Q000175:diagnosis*; D010455:Peptides / Q000097:blood*; D011237:Predictive Value of Tests
D015415:Biomarkers; D010455:Peptides