Effects of heptaminol AMP amidate on T cell populations of peripheral blood lymphocytes and splenocytes in mice.
Heptaminol AMP amidate (HAA), a nucleotide derivative increased the percentage of T cell surface phenotypes on peripheral blood lymphocytes (PBL) of mice primed with sheep red blood cells. The T cell surface phenotypes Thy1.2, Lyt1, L3T4 and Lyt2 increased on the PBL of HAA administered mice to 136, 145, 144 and 153%, respectively over those on the PBL of control mice.
Ueno
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Laboratory of Biochemical Pharmacology and Biotoxicology, Faculty of Pharmaceutical Sciences, Chiba University, Japan.
Saha
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AR
Satoh
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Kitagawa
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D000249:Adenosine Monophosphate / Q000031:analogs & derivatives* / Q000494:pharmacology; D000276:Adjuvants, Immunologic / Q000494:pharmacology; D000818:Animals; D000941:Antigens / Q000008:administration & dosage; D000945:Antigens, Differentiation, T-Lymphocyte; D004912:Erythrocytes / Q000276:immunology; D006535:Heptaminol / Q000031:analogs & derivatives* / Q000494:pharmacology; D051379:Mice; D008807:Mice, Inbred BALB C; D010641:Phenotype; D012756:Sheep; D013154:Spleen / Q000166:cytology / Q000187:drug effects / Q000276:immunology; D016176:T-Lymphocyte Subsets / Q000166:cytology / Q000187:drug effects* / Q000276:immunology
D000276:Adjuvants, Immunologic; D000941:Antigens; D000945:Antigens, Differentiation, T-Lymphocyte; D006535:Heptaminol; D000249:Adenosine Monophosphate; C053918:heptaminol AMP amidate