title: [Phototoxic dermatitis following the use of Ammi majus fruit for vitiligo].
abstract: The injudicious use of a systemically administered herb containing psoralens derived from the fruits of Ammi majus in combination with exposure of the skin to the sun caused a severe phototoxic dermatitis in a Moroccan patient with vitiligo. She was disappointed in the treatment by the dermatologist. A family member advised her to start the treatment with herbs. The identification of the herbs by microscopic, chromatographic and biological techniques demonstrated that they contained the linear furanocoumarins (psoralens) 5-MOP, 8-MOP and oxypeucedanin each in a concentration of approx. 1%. Because of the large immigrant population in our country we expect to see more cases in the future.
authors.affiliation: Academisch Ziekenhuis, afd. Dermatologie, Utrecht.
authors.forename: P M
authors.initials: PM
authors.lastname: Ossenkoppele
authors.forename: W G
authors.initials: WG
authors.lastname: van der Sluis
authors.forename: W A
authors.initials: WA
authors.lastname: van Vloten
mesh_terms: D000328:Adult; D005260:Female; D011564:Furocoumarins / Q000032:analysis; D006801:Humans; D010787:Photosensitivity Disorders / Q000139:chemically induced*; D010946:Plants, Medicinal / Q000032:analysis; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced*; D014820:Vitiligo / Q000628:therapy*
chemical_list: D011564:Furocoumarins