title: [Regulatory disorders of locomotor functions in dogs during prolonged irradiation in a wide range of dose rates].
abstract: A biphase pattern of the development of locomotor disturbances, connected with the primary response and cerebral radiation syndrome, was demonstrated in experiments with dogs subjected to prolonged irradiation, just as it was observed after acute exposure. Dose thresholds for the development of these states were somewhat higher with the prolonged irradiation. The time of the appearance of disturbances increased due to the delay of achievement the dose threshold increase with dose-rate decrease, the time interval needed for the development of the corresponding pathological process being unchanged. Due to the repair process the above syndromes were not manifested until the appropriate dose-rate thresholds were reached.
authors.forename: V N
authors.initials: VN
authors.lastname: Malakhovskiĭ
authors.forename: M I
authors.initials: MI
authors.lastname: Bokk
authors.forename: A A
authors.initials: AA
authors.lastname: Sergeev
mesh_terms: D000208:Acute Disease; D000818:Animals; D001794:Blood Pressure / Q000502:physiology / Q000528:radiation effects; D004285:Dogs; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D008124:Locomotion / Q000502:physiology / Q000528:radiation effects*; D008297:Male; D009069:Movement Disorders / Q000503:physiopathology*; D011833:Radiation Injuries, Experimental / Q000503:physiopathology*; D013997:Time Factors