title: The organization of the gene for the human cerebroside sulfate activator protein.
abstract: The organization of 14 exons covering 97% of the cDNA sequence of human cerebroside sulfate activator protein precursor has been determined from two overlapping EMBL-4 human genomic clones extending over 17 kb. All exons and exon/intron splice junctions and five introns were sequenced. Exon 8 consists of only 9 bp and is involved in alternative splicing which generates three different mRNAs of cerebroside sulfate activator precursor.
authors.affiliation: Institut für Organische Chemie und Biochemie, Universität Bonn, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Holtschmidt
authors.forename: K
authors.initials: K
authors.lastname: Sandhoff
authors.forename: W
authors.initials: W
authors.lastname: Fürst
authors.forename: H Y
authors.initials: HY
authors.lastname: Kwon
authors.forename: D
authors.initials: D
authors.lastname: Schnabel
authors.forename: K
authors.initials: K
authors.lastname: Suzuki
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D001921:Brain / Q000378:metabolism; D002554:Cerebrosides / Q000235:genetics*; D005091:Exons; D015698:Genomic Library; D006023:Glycoproteins / Q000235:genetics*; D006801:Humans; D007438:Introns; D007668:Kidney / Q000378:metabolism; D008969:Molecular Sequence Data; D012326:RNA Splicing; D012333:RNA, Messenger / Q000378:metabolism; D015183:Restriction Mapping; D049231:Saposins; D049128:Sphingolipid Activator Proteins
chemical_list: D002554:Cerebrosides; D006023:Glycoproteins; C483345:PSAP protein, human; D012333:RNA, Messenger; D049231:Saposins; D049128:Sphingolipid Activator Proteins