title: Is 20S RNA naked?
abstract: The 20S RNA of Saccharomyces cerevisiae is a single-stranded, circular RNA virus. A previous study suggested that this RNA is part of a 32S ribonucleoprotein particle, being associated with multiple copies of a 23-kilodalton protein. We show here that this protein is, in fact, the chromosome-encoded heat shock protein Hsp26. Furthermore, it is apparently not associated with 20S RNA and plays no obvious role in the life cycle of the virus.
authors.affiliation: Section on Genetics of Simple Eukaryotes, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892.
authors.forename: W R
authors.initials: WR
authors.lastname: Widner
authors.forename: Y
authors.initials: Y
authors.lastname: Matsumoto
authors.forename: R B
authors.initials: RB
authors.lastname: Wickner
mesh_terms: D002499:Centrifugation, Density Gradient; D015825:Chromosomes, Fungal; D006360:Heat-Shock Proteins / Q000235:genetics / Q000302:isolation & purification; D015151:Immunoblotting; D008970:Molecular Weight; D012331:RNA, Fungal / Q000235:genetics*; D012367:RNA, Viral / Q000235:genetics*; D012261:Ribonucleoproteins / Q000235:genetics / Q000302:isolation & purification; D012441:Saccharomyces cerevisiae / Q000235:genetics*
chemical_list: D006360:Heat-Shock Proteins; D012331:RNA, Fungal; D012367:RNA, Viral; D012261:Ribonucleoproteins