title: Effectiveness of ofloxacin in the treatment of Chlamydia trachomatis and Neisseria gonorrhoeae cervical infection.
abstract: Forty patients with cervical infection caused by Chlamydia trachomatis were treated with ofloxacin (20) or doxycycline (20). Ofloxacin was successful in eradicating C. trachomatis from all 20 (100%) patients. Doxycycline was effective in 18 of 20 (90%) patients. Three patients had a concomitant cervical gonococcal infection. All three were successfully treated: one with ofloxacin and two with doxycycline. Ofloxacin, 300 mg, taken twice daily for 7 days, is effective in eradicating endocervical C. trachomatis infection.
authors.affiliation: Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030.
authors.forename: S
authors.initials: S
authors.lastname: Faro
authors.forename: M G
authors.initials: MG
authors.lastname: Martens
authors.forename: M
authors.initials: M
authors.lastname: Maccato
authors.forename: H A
authors.initials: HA
authors.lastname: Hammill
authors.forename: S
authors.initials: S
authors.lastname: Roberts
authors.forename: G
authors.initials: G
authors.lastname: Riddle
mesh_terms: D000293:Adolescent; D000328:Adult; D002690:Chlamydia Infections / Q000188:drug therapy* / Q000382:microbiology; D002692:Chlamydia trachomatis; D004318:Doxycycline / Q000627:therapeutic use; D004341:Drug Evaluation; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D015242:Ofloxacin / Q000627:therapeutic use*; D011897:Random Allocation; D002575:Uterine Cervicitis / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D015242:Ofloxacin; D004318:Doxycycline