A study of the effect of kHz ultrasound on the mutation rate of Salmonella typhimurium TA102.
Free radicals, induced by ionising radiation or generated by chemical systems, are known to produce DNA damage that may result in mutation. An in vitro study was carried out to discover whether free radicals produced from water using kHz ultrasound increased the mutation rate of Salmonella typhimurium above the spontaneous reversion rate. Results showed that the mutation rate of S. typhimurium did not increase under these conditions. It is concluded that dental ultrasound is not mutagenic to the dental soft tissues under normal conditions of use.
Hirst
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D012534:Dental Scaling / Q000295:instrumentation; D005609:Free Radicals; D009152:Mutagenicity Tests; D012390:Root Canal Therapy / Q000295:instrumentation; D012486:Salmonella typhimurium / Q000235:genetics*; D014465:Ultrasonics / Q000009:adverse effects*
D005609:Free Radicals