title: Motion sickness. Helping patients tolerate the ups and downs.
abstract: The sensory conflict theory provides a useful framework for understanding motion sickness. Few modifications of this model have been proposed since its publication. The weak link in the study of motion sickness has been the failure to delineate the anatomic structures that correspond to the model's components. Effective pharmacotherapy is available for treatment of motion sickness. The choice should be based on the need to provide prophylaxis for or treatment of symptoms and on the side effect profile of the drug.
authors.affiliation: Department of Otolaryngology, Hospital for Sick Children, University of Toronto Faculty of Medicine.
authors.forename: M J
authors.initials: MJ
authors.lastname: Ruckenstein
authors.forename: R V
authors.initials: RV
authors.lastname: Harrison
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology; D000662:Amphetamines / Q000008:administration & dosage / Q000627:therapeutic use*; D001521:Behavior Therapy / Q000379:methods; D004502:Education, Medical, Continuing; D006633:Histamine Antagonists / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D009041:Motion Sickness / Q000188:drug therapy* / Q000503:physiopathology / Q000628:therapy; D010276:Parasympatholytics / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D000662:Amphetamines; D006633:Histamine Antagonists; D010276:Parasympatholytics