title: [Endogenous factors in the pathogenesis of vulvar cancer].
abstract: In 59 patients with cancer of the vulva, levels of ACTH, FSH, thyrotropin, prolactin, somatotropin, cortisol, triiodothyronine, thyroxin, testosterone, progesterone and estradiol were measured in blood whereas those of 17-HOCS, 17-CS and estrogens--in urine. Hormonal imbalance was established at all levels of the endocrine system, viz. increased concentrations of cortisol and 17-HOCS, decreased ACTH level, shift in androgen/estrogen and androgen/progestin ratios towards testosterone, lowered FSH and somatotropin output and elevated blood-prolactin level.
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Sidorenko
authors.forename: G A
authors.initials: GA
authors.lastname: Nerodo
authors.forename: G Ia
authors.initials: GIa
authors.lastname: Mar'ianovskaia
authors.forename: G Ia
authors.initials: GIa
authors.lastname: Cherniavskaia
authors.forename: A M
authors.initials: AM
authors.lastname: Tiutiunova
mesh_terms: D005260:Female; D006728:Hormones / Q000032:analysis; D006801:Humans; D009367:Neoplasm Staging; D014846:Vulvar Neoplasms / Q000209:etiology* / Q000378:metabolism / Q000473:pathology
chemical_list: D006728:Hormones