A defective proviral DNA with a 2.6-kb deletion of human immunodeficiency virus type 1 (HIV-1) in a persistently HIV-1 infected cell clone.
A cell line (H2-5) producing defective doughnut-shaped particles of human immunodeficiency virus type I (HIV-1) was found to contain proviral DNA with a large deletion of 2558 bases, corresponding to the 3' half of pol gene, the vif and vpr genes, and the 5' terminal of the tat gene.
Imai
H
H
Section of Serology, Hokkaido University, Sapporo, Japan.
Maotani-Imai
K
K
Shin
Y S
YS
Ikuta
K
K
Suehiro
S
S
Kurimura
T
T
Kato
S
S
Hirai
K
K
D000595:Amino Acid Sequence; D001483:Base Sequence; D015152:Blotting, Northern; D015139:Blotting, Southern; D002460:Cell Line; D002872:Chromosome Deletion; D002999:Clone Cells; D004279:DNA, Viral / Q000235:genetics* / Q000302:isolation & purification; D003673:Defective Viruses / Q000235:genetics*; D005814:Genes, Viral; D015497:HIV-1 / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011533:Proviruses / Q000235:genetics*; D012367:RNA, Viral / Q000235:genetics / Q000302:isolation & purification; D015183:Restriction Mapping; D014158:Transcription, Genetic
D004279:DNA, Viral; D012367:RNA, Viral