title: [SPECT with 99m-TC HM PAO in the study of classical hemicrania].
abstract: Five patients presenting with migraine attacks underwent Electroencephalography (EEC), Computed Tomography (CT) and Single Photon Emission Tomography (SPECT) with 99mTc-HM PAO. EEG and SPECT were subsequently repeated in the intercritical period. We observed that: two patients only showed non-specific abnormalities in EEG; scans were normal in all patients; all subjects exhibited diffuse cortical hypoperfusion. A strong correlation was always found between clinical presentation and hemispheric impairment. One patient exhibited asymmetrical perfusion between cerebellum hemispheres; intercritical SPECT showed homogeneous distribution of the radio-tracer in four patients. In the last one minimal residual hypoperfusion was observed, although less marked than in the acute phase. Therefore SPECT with 99mTc-HM PAO can be reasonably employed as the examination of choice when a migraine attack is clinically suspected, because of its reproducibility and reliability. It can be easily performed in every nuclear medical center supplied with modern tomographic gamma-cameras.
authors.affiliation: Medicina Nucleare e Radioterapia, Ospedale Civile, Sondrio.
authors.forename: S
authors.initials: S
authors.lastname: Tomaiolo
authors.forename: F
authors.initials: F
authors.lastname: Stiglich
authors.forename: F
authors.initials: F
authors.lastname: Bonomo
authors.forename: C
authors.initials: C
authors.lastname: Barbonetti
authors.forename: I
authors.initials: I
authors.lastname: Di Lorenzo
authors.forename: R
authors.initials: R
authors.lastname: Campani
authors.forename: O
authors.initials: O
authors.lastname: Bottinelli
authors.forename: G
authors.initials: G
authors.lastname: Bottinelli
mesh_terms: D000293:Adolescent; D000328:Adult; D002560:Cerebrovascular Circulation; D004569:Electroencephalography; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D008881:Migraine Disorders / Q000000981:diagnostic imaging* / Q000503:physiopathology; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime