title: Giant perforations of duodenal ulcer.
abstract: Over a period of eleven years, eight patients were treated for duodenal ulcer perforation measuring more than one centimetre in diameter. In five of these patients, the perforation was sealed using a jejunal loop as serosal onlay patch; one patient underwent gastrectomy and in two patients catheter duodenostomy was done. Two patients died, both due to renal failure. The six surviving patients were discharged with the advice for a subsequent 'ulcer-curing' operation after six months. Two patients developed life threatening complications during this waiting period and one of these died. Giant perforations of duodenal ulcer can safely be closed using a jejunal loop as serosal patch. Delay in doing the second stage definitive surgery for the ulcer may be dangerous.
authors.affiliation: Department of Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh.
authors.forename: A
authors.initials: A
authors.lastname: Chaudhary
authors.forename: S M
authors.initials: SM
authors.lastname: Bose
authors.forename: N M
authors.initials: NM
authors.lastname: Gupta
authors.forename: J D
authors.initials: JD
authors.lastname: Wig
authors.forename: S K
authors.initials: SK
authors.lastname: Khanna
mesh_terms: D000368:Aged; D004381:Duodenal Ulcer / Q000150:complications*; D004385:Duodenostomy; D005260:Female; D005743:Gastrectomy; D006396:Hematemesis / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010439:Peptic Ulcer Perforation / Q000150:complications*