[Concentration of locally applied Indometacin eyedrops for the inhibition of prostaglandin synthesis in the eye].
Indomethacin is well known as local eye drug for the prevention of cystoid macular oedema. The concentration is 50 mg/5 ml. Another inhibitor of the prostaglandin synthesis is flurbiprofen; its concentration is 1.5 mg/5 ml. Indomethacin is a suspension and available in different concentrations dependent on the shaking procedure. We measured the concentration of indomethacin in one single eyedrop from a full bottle, half full and a nearly empty bottle. After correct shaking the concentration of indomethacin was between 48 and 53 mg/5 ml.
Strobel
J
J
Universitäts-Augenklinik Giessen.
D007213:Indomethacin / Q000737:chemistry*; D009883:Ophthalmic Solutions / Q000737:chemistry*
D009883:Ophthalmic Solutions; D007213:Indomethacin