title: [Prognosis and differential diagnosis of protracted pneumonia using the indicators of inhibition of proteolytic activity].
abstract: Ninety-eight patients with protracted pneumonia were examined for activity of the system proteinases--proteinases inhibitors in bronchial secretion. Correlation between antitrypsin activity (ATA) and activity of trypsin-like proteinases (TLP) was most demonstrable. By calculating the ratio ATA/TLP the index of inhibition of proteolytic activity was derived applied in diagnosis of protracted and chronic pneumonias. ++Clinico-biochemical parallels obtained in patients with protracted pneumonia upon 1.5-year follow-up led the authors to conclusion that if the above index remains low for 1 month of the adequate therapy protracted pneumonia tends to chronicity. If the follow-up results are indicative of increasing index, pneumonia may terminate in recovery.
authors.forename: V M
authors.initials: VM
authors.lastname: Provotorov
authors.forename: G G
authors.initials: GG
authors.lastname: Semenkova
mesh_terms: D000293:Adolescent; D000328:Adult; D001992:Bronchoalveolar Lavage Fluid / Q000201:enzymology*; D002908:Chronic Disease; D003937:Diagnosis, Differential; D006801:Humans; D008875:Middle Aged; D010196:Pancreatic Elastase / Q000378:metabolism*; D011014:Pneumonia / Q000175:diagnosis* / Q000201:enzymology; D011379:Prognosis; D014357:Trypsin / Q000378:metabolism*; D000515:alpha 1-Antitrypsin / Q000032:analysis / Q000378:metabolism*
chemical_list: D000515:alpha 1-Antitrypsin; D010196:Pancreatic Elastase; D014357:Trypsin