Acute pulmonary hypertensive crisis in a patient with primary pulmonary hypertension treated by both epoprostenol (prostacyclin) and nitroprusside.
A 19-year-old girl was diagnosed as having primary pulmonary hypertension that was confirmed by right heart catheterization. Acute right heart failure was associated with syncope. Stabilization, while not achieved with intravenous epoprostenol (Prostacyclin) alone, was achieved with intravenous prostacyclin and nitroprusside.
Scott
J P
JP
Heart-lung Transplant Research Unit, Papworth Hospital, Cambridge, England.
Higenbottam
T W
TW
Smyth
R L
RL
Wallwork
J
J
D000328:Adult; D002303:Cardiac Output, Low / Q000209:etiology; D004359:Drug Therapy, Combination; D011464:Epoprostenol / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications / Q000188:drug therapy*; D009599:Nitroprusside / Q000627:therapeutic use*; D013575:Syncope / Q000209:etiology; D016278:Ventricular Function, Right / Q000502:physiology
D009599:Nitroprusside; D011464:Epoprostenol