title: Daily variations in concentration of vasoactive intestinal polypeptide immunoreactivity in discrete brain areas of the rat.
abstract: The concentration of VIP-like immunoreactivity (VIP-LI) was determined by radioimmunoassay at various times of the day in 11 discrete brain areas and in the antehypophysis of rats maintained on a regular 12 h/12 h light-dark cycle. In the suprachiasmatic and periventricular nuclei the VIP-LI increased during the dark period and decreased during the subsequent light period. In addition, the VIP-LI exhibited complex variations in the locus coeruleus, the periaqueductal gray matter and the paraventricular nucleus, but did not change in the other areas investigated.
authors.affiliation: Département de Médecine Expérimentale, INSERM U 52-CNRS URA 1195, Université Claude Bernard, Lyon, France.
authors.forename: A
authors.initials: A
authors.lastname: Morin
authors.forename: L
authors.initials: L
authors.lastname: Denoroy
authors.forename: M
authors.initials: M
authors.lastname: Jouvet
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D001923:Brain Chemistry; D001933:Brain Stem / Q000737:chemistry; D002940:Circadian Rhythm; D008297:Male; D009419:Nerve Tissue Proteins / Q000032:analysis; D009928:Organ Specificity; D010903:Pituitary Gland, Anterior / Q000033:anatomy & histology; D011863:Radioimmunoassay; D051381:Rats; D011919:Rats, Inbred Strains; D014660:Vasoactive Intestinal Peptide / Q000032:analysis*
chemical_list: D009419:Nerve Tissue Proteins; D014660:Vasoactive Intestinal Peptide