Localization of monocyte chemotactic protein-1 gene (SCYA2) to human chromosome 17q11.2-q21.1.
Monocyte chemotactic protein-1 (MCP-1) is a member of the small inducible gene (SIG) family. It has been shown to play a role in the recruitment of monocytes to sites of injury and infection. By analysis of a panel of somatic cell hybrids, we have localized the MCP-1 gene, designated SCYA2, to human chromosome 17. In situ hybridization confirmed this assignment and further localized the gene to 17q11.2-q21.1.
Mehrabian
M
M
Division of Cardiology, University of California, Los Angeles 90024.
Sparkes
R S
RS
Mohandas
T
T
Fogelman
A M
AM
Lusis
A J
AJ
D000818:Animals; D001483:Base Sequence; D018932:Chemokine CCL2; D002630:Chemotactic Factors / Q000235:genetics*; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002886:Chromosomes, Human, Pair 17; D005796:Genes; D006801:Humans; D006822:Hybrid Cells; D051379:Mice; D008969:Molecular Sequence Data; D009000:Monocytes
D018932:Chemokine CCL2; D002630:Chemotactic Factors