Miconazole corneal toxicity.
A case of miconazole corneal toxicity is reported. This was seen in a patient who had had a penetrating keratoplasty for Acanthamoeba keratitis; the patient was treated with miconazole postoperatively. The miconazole toxicity manifested itself as a row of pinpoint vesicular elevations in the corneal epithelium associated with surrounding superficial punctate keratitis. Stopping the miconazole led to the resolution of the corneal epithelial changes.
Zaidman
G W
GW
Department of Ophthalmology, Westchester County Medical Center, New York Medical College, Valhalla 10595.
D015823:Acanthamoeba Keratitis / Q000188:drug therapy / Q000601:surgery; D000328:Adult; D005260:Female; D006801:Humans; D007634:Keratitis / Q000139:chemically induced*; D015948:Keratoplasty, Penetrating; D008825:Miconazole / Q000009:adverse effects* / Q000627:therapeutic use; D011182:Postoperative Care
D008825:Miconazole