Differential susceptibility of two stocks of Mongolian gerbils (Meriones unguiculatus) to Leptospira.
Mongolian gerbils (Meriones unguiculatus) of Tumble Blook (TUM) and Japan Medical Science (JMS) stocks were compared with regard to susceptibility to Leptospira interrogans serovar copenhageni. The TUM gerbil died 6 to 9 d after intraperitoneal inoculation with 10 organisms, showing jaundice and systemic hemorrhage. However, 25% of the JMS gerbils survived infection with 10(3) or 10(4) organisms and there was no fatal case after infection with 10(2) organisms.
Yukawa
M
M
Laboratory of Biomedical Science, Nihon University, Veterinary School, Japan.
D000818:Animals; D004198:Disease Susceptibility; D005260:Female; D005849:Gerbillinae; D008297:Male; D012376:Rodent Diseases / Q000276:immunology*; D014895:Weil Disease / Q000276:immunology / Q000662:veterinary*