Allosteric mechanism of enhancer action?
A recurrent theme in molecular biology is 'action at a distance' along DNA. Why can some regulatory DNA sequences (enhancers) work at a great distance from the target of regulation? As one possible solution to this question we shall consider an allosteric mechanism of enhancer action focused on eukaryotic transcriptional enhancers.
Studitsky
V M
VM
W.A. Engelhardt Institute of Molecular Biology, Academy of Sciences of the USSR, Moscow.
D000494:Allosteric Regulation; D001665:Binding Sites; D004247:DNA / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000235:genetics* / Q000378:metabolism; D004742:Enhancer Elements, Genetic; D011401:Promoter Regions, Genetic
D004268:DNA-Binding Proteins; D004247:DNA