title: Biocompatibility of diamond-like carbon coating.
abstract: Diamond-like carbon coating is an inert, impervious hydrocarbon coating with properties suitable for use in the biomedical field, particularly in orthopaedic implants. Mouse peritoneal macrophages and mouse fibroblasts were grown on tissue culture plates treated with diamond-like carbon and the biocompatibility assessed both biochemically and morphologically. This investigation showed that diamond-like carbon coating caused no adverse effects on cells in culture and therefore merits further investigation as a coating for biomedical use.
authors.affiliation: University of Cambridge Orthopaedic Research Unit, Addenbrooke's Hospital, UK.
authors.forename: L A
authors.initials: LA
authors.lastname: Thomson
authors.forename: F C
authors.initials: FC
authors.lastname: Law
authors.forename: N
authors.initials: N
authors.lastname: Rushton
authors.forename: J
authors.initials: J
authors.lastname: Franks
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D002244:Carbon; D002478:Cells, Cultured; D005260:Female; D005347:Fibroblasts / Q000201:enzymology; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D008264:Macrophages / Q000201:enzymology; D051379:Mice; D009984:Orthopedic Fixation Devices; D010529:Peritoneal Cavity / Q000166:cytology; D019736:Prostheses and Implants
chemical_list: D001672:Biocompatible Materials; D002244:Carbon; D007770:L-Lactate Dehydrogenase