title: Biogenic amines: their occurrence, biosynthesis and metabolism in the locust, Schistocerca gregaria, by gas chromatography-negative-ion chemical ionisation mass spectrometry.
abstract: Extraction-derivatisation techniques have been developed for the unambiguous identification of biogenic amines, and their putative amino acid precursors and metabolites (both major and minor), in single ventral thoracic nerve cords of the locust. Schistocerca gregaria, by the use of gas chromatography-negative-ion chemical ionisation mass spectrometry with selected ion monitoring. In addition the configuration of that enantiomer of p-octopamine present in the thoracid nervous system of the locust was established as R using the chiral derivatisation reagent, (-)-heptafluorobutyrylphenylalanyl chloride.
authors.affiliation: Department of Pharmacy, University of Strathclyde, Glasgow, U.K.
authors.forename: R G
authors.initials: RG
authors.lastname: MacFarlane
authors.forename: J M
authors.initials: JM
authors.lastname: Midgley
authors.forename: D G
authors.initials: DG
authors.lastname: Watson
authors.forename: P D
authors.initials: PD
authors.lastname: Evans
mesh_terms: D000107:Acetylation; D000596:Amino Acids / Q000032:analysis / Q000378:metabolism; D000818:Animals; D001679:Biogenic Amines / Q000032:analysis* / Q000096:biosynthesis / Q000378:metabolism; D002395:Catecholamines / Q000032:analysis / Q000378:metabolism; D008401:Gas Chromatography-Mass Spectrometry; D006110:Grasshoppers / Q000378:metabolism*; D008968:Molecular Conformation; D009420:Nervous System / Q000737:chemistry; D009655:Octopamine / Q000032:analysis; D010636:Phenols / Q000032:analysis / Q000378:metabolism; D012701:Serotonin / Q000031:analogs & derivatives / Q000032:analysis / Q000378:metabolism
chemical_list: D000596:Amino Acids; D001679:Biogenic Amines; D002395:Catecholamines; D010636:Phenols; D009655:Octopamine; D012701:Serotonin; C006389:N-acetylserotonin