[Phototoxic dermatitis following the use of Ammi majus fruit for vitiligo].
The injudicious use of a systemically administered herb containing psoralens derived from the fruits of Ammi majus in combination with exposure of the skin to the sun caused a severe phototoxic dermatitis in a Moroccan patient with vitiligo. She was disappointed in the treatment by the dermatologist. A family member advised her to start the treatment with herbs. The identification of the herbs by microscopic, chromatographic and biological techniques demonstrated that they contained the linear furanocoumarins (psoralens) 5-MOP, 8-MOP and oxypeucedanin each in a concentration of approx. 1%. Because of the large immigrant population in our country we expect to see more cases in the future.
Ossenkoppele
P M
PM
Academisch Ziekenhuis, afd. Dermatologie, Utrecht.
van der Sluis
W G
WG
van Vloten
W A
WA
D000328:Adult; D005260:Female; D011564:Furocoumarins / Q000032:analysis; D006801:Humans; D010787:Photosensitivity Disorders / Q000139:chemically induced*; D010946:Plants, Medicinal / Q000032:analysis; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced*; D014820:Vitiligo / Q000628:therapy*
D011564:Furocoumarins