Renal cell carcinoma involving penis and testis: unusual initial presentations of metastatic disease.
Solitary parenchymal metastases of renal cell carcinoma to the penis or testis are rare. We report 1 case of each: in one instance the patient presented with priapism and an asymptomatic primary tumor; in the other, the metastasis presented as an acute change in a long-standing hydrocele more than one year after nephrectomy. Both patients had either positive margins at resection or recurrence after resection of the metastasis. While long-term, disease-free survival has been reported after orchiectomy for isolated metastatic disease, penile involvement appears to carry a very poor prognosis.
Daniels
G F
GF
Department of Urology, Northwestern University Medical School, Chicago, Illinois.
Schaeffer
A J
AJ
D000368:Aged; D000369:Aged, 80 and over; D002292:Carcinoma, Renal Cell / Q000473:pathology / Q000556:secondary*; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008297:Male; D010412:Penile Neoplasms / Q000473:pathology / Q000556:secondary*; D013736:Testicular Neoplasms / Q000473:pathology / Q000556:secondary*