Lactic acidosis associated with high-dose niacin therapy.
We have reported a case of lactic acidosis induced by ingestion of sustained-release nicotinic acid. Prompt recovery followed treatment with glucose-containing fluids and discontinuation of nicotinic acid therapy.
Earthman
T P
TP
Department of Internal Medicine, St. Joseph Hospital, Houston, Tex.
Odom
L
L
Mullins
C A
CA
D000140:Acidosis, Lactic / Q000097:blood / Q000139:chemically induced* / Q000175:diagnosis / Q000378:metabolism; D000328:Adult; D003692:Delayed-Action Preparations; D006801:Humans; D006949:Hyperlipidemias / Q000188:drug therapy; D007773:Lactates / Q000097:blood / Q000378:metabolism; D008297:Male; D009525:Niacin / Q000008:administration & dosage / Q000009:adverse effects*; D012008:Recurrence
D003692:Delayed-Action Preparations; D007773:Lactates; D009525:Niacin