Direct immunofluorescence testing of haired skin, nasal planum, and footpads of clinically normal woodchuck hepatitis virus-infected and non-infected woodchucks.
The purpose of this study was to determine the frequency of immunoreactant deposition in the skin, footpad, and nasal planum of 10 clinically normal, non WHV-infected woodchucks. The second part of the study investigated the frequency of immunoreactant deposition at the same sites in clinically normal, WHV-infected woodchucks, and compared these results with those reported in humans. Direct immunofluorescence testing of the haired skin, footpad, and nasal planum of all normal and 9 of the 10 WHV-infected woodchucks was negative. The footpad of 1 WHV-infected woodchuck revealed immunoreactant deposition in the walls of the superficial dermal blood vessels.
Panich
R
R
Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.
Scott
D W
DW
Smith
C A
CA
Tennant
B C
BC
D000818:Animals; D005260:Female; D005455:Fluorescent Antibody Technique; D005528:Foot; D006197:Hair; D015613:Hepadnaviridae; D006524:Hepatitis, Viral, Animal / Q000276:immunology*; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D008392:Marmota / Q000276:immunology*; D009666:Nose; D012867:Skin / Q000276:immunology*
D007136:Immunoglobulins