title: [Is Cerebellar Soluble Lectin a major immunological target in multiple sclerosis?].
abstract: In a recent paper: (Zanetta J.P. et al., Lancet, 1990, 335, 1482-1484) the authors showed that antibodies against the mannose-binding protein Cerebellar Soluble Lectin (CSL) are present in the cerebrospinal fluid of most multiple sclerosis patients. Herein, the properties and roles of the molecule as they are currently understood are described; hypotheses suggested by the consistent presence of anti-CSL antibodies in multiple sclerosis patients are discussed.
authors.forename: J P
authors.initials: JP
authors.lastname: Zanetta
authors.forename: J M
authors.initials: JM
authors.lastname: Warter
authors.forename: S
authors.initials: S
authors.lastname: Lehmann
authors.forename: S
authors.initials: S
authors.lastname: Kuchler
authors.forename: G
authors.initials: G
authors.lastname: Vincendon
mesh_terms: D000906:Antibodies / Q000032:analysis; D006801:Humans; D007159:Immunologic Tests; D037102:Lectins / Q000032:analysis / Q000276:immunology* / Q000502:physiology; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid / Q000276:immunology* / Q000503:physiopathology
chemical_list: D000906:Antibodies; D037102:Lectins; C059525:cerebellar soluble lectin