title: Xenopus transcription factor IIIC (TFIIIC) specifically interacts with the "B" block region of the TFIIIA gene.
abstract: Transcription factors IIIC (TFIIIC), TFIIIB and RNA polymerase III are commonly required for class III gene transcription in vitro. To understand the diversity and specificity of Xenopus TFIIIC, we have further characterized this factor. Our analyses indicate that a partially purified TFIIIC fraction contains an activity which specifically recognizes the "B" block element of TFIIIA gene. Stable complex formation assays with HeLa cell extracts demonstrate that the TFIIIA gene can stably sequester TFIIIC. off
authors.affiliation: Eye Research Institute of Oakland University, Rochester, MI 48309.
authors.forename: B S
authors.initials: BS
authors.lastname: Shastry
authors.forename: Z G
authors.initials: ZG
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001483:Base Sequence; D001665:Binding Sites; D003001:Cloning, Molecular; D004247:DNA / Q000235:genetics / Q000378:metabolism; D003850:Deoxyribonuclease I; D005260:Female; D005796:Genes; D008969:Molecular Sequence Data; D009865:Oocytes / Q000502:physiology; D011485:Protein Binding; D012320:RNA Polymerase III / Q000302:isolation & purification / Q000378:metabolism*; D012343:RNA, Transfer / Q000235:genetics / Q000378:metabolism; D035582:Transcription Factor TFIIIA; D014157:Transcription Factors / Q000235:genetics* / Q000378:metabolism*; D019474:Transcription Factors, TFIII; D014982:Xenopus laevis; D000098832:Transcription Factor TFIIIC
chemical_list: D035582:Transcription Factor TFIIIA; D014157:Transcription Factors; D019474:Transcription Factors, TFIII; D000098832:Transcription Factor TFIIIC; D004247:DNA; D012343:RNA, Transfer; D012320:RNA Polymerase III; D003850:Deoxyribonuclease I