title: [The treatment procedure in olfactory (esthesioneurogenic) tumors].
abstract: In 1968-1988, eleven cases of olfactory neurogenic tumors were seen at The All-Union Center for Oncology Research, Moscow which made up 9.5% of the total of nasal cavity cancers. Morphologically, esthesioneurocytoma was diagnosed in two patients whereas esthesioneuroblastoma--in nine. Four patients received combined therapy while seven--chemotherapy and radiation. Progression of the disease was registered in 7 out of 11 patients: in 3 of 4 cases receiving combination treatment and in 4 out of 7 those treated conservatively. Four cases died within 7-29 months while 7 remain alive: two patients at 18 and 156 months following combined therapy and 5--at 18, 18, 24, 84 and 132 months after chemoradiation treatment. Radiation alone proved the best therapeutic option. Surgery is justified in cases with residual tumor as second-line procedure.
authors.forename: B M
authors.initials: BM
authors.lastname: Aliev
authors.forename: N A
authors.initials: NA
authors.lastname: Probatova
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003131:Combined Modality Therapy / Q000379:methods; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity; D009297:Nasal Mucosa; D018241:Neuroectodermal Tumors, Primitive, Peripheral / Q000628:therapy*; D009669:Nose Neoplasms / Q000628:therapy*; D011182:Postoperative Care / Q000379:methods; D011300:Preoperative Care / Q000379:methods; D011879:Radiotherapy Dosage; D012074:Remission Induction