Complexation studies on inositol-phosphates. II. Alkali-metal complexes of D-myo-inositol 1,2,6 trisphosphate.
The complexation properties of the D-myo-inositol 1,2,6 trisphosphate (Ins(1,2,6)P3) towards Li+, Na+, K+, Rb+, and Cs+ cations were studied at 25 degrees C in a 0.1 M tetra-n-butylammonium bromide medium. For all cations, mononuclear and protonated species were found. For smaller cations (Li+, Na+, and K+) a dinuclear complex was also put into evidence. The main characteristic of the complexes is its high stability; and of the ligand, its nonselectivity. The Ins(1,2,6)P3-K system was ascertained using Sammartano's method which additionally enabled the influence of various K+ concentrations on the protonations constants to be considered.
Bieth
H
H
Laboratoire de Chimie Analytique, Faculté de Pharmacie de Strasbourg Illkirch, France.
Schlewer
G
G
Spiess
B
B
D002414:Cations, Monovalent; D002586:Cesium / Q000737:chemistry; D006859:Hydrogen; D007295:Inositol Phosphates / Q000737:chemistry*; D008094:Lithium / Q000737:chemistry; D008670:Metals / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D011188:Potassium / Q000737:chemistry; D011199:Potentiometry; D012413:Rubidium / Q000737:chemistry; D012964:Sodium / Q000737:chemistry; D012984:Software
D002414:Cations, Monovalent; D007295:Inositol Phosphates; D008670:Metals; D002586:Cesium; D006859:Hydrogen; D008094:Lithium; D012964:Sodium; D012413:Rubidium; D011188:Potassium; C059368:atrinositol