title: Electrooculography and discriminant analysis in Duane's syndrome and sixth-cranial-nerve palsy.
abstract: Eye-movement recordings may be helpful in the differentiation of Duane's syndrome from sixth-cranial-nerve palsy. Voluntary horizontal saccades were recorded and quantitated by electrooculography in 18 patients with unilateral type I Duane's syndrome and in 25 patients with sixth-nerve palsy. When ranges of abduction were matched, the peak velocities of abducting saccades in affected eyes were decreased equally in both groups. However, the peak velocities of adducting saccades in sound eyes were slowed in patients with Duane's syndrome. Because the standard deviations in saccadic velocities are large, computer-based, stepwise discriminant analyses were performed to identify the variables that proved to be useful in differentiating the two disorders. By entering these variables into the discriminant functions that were created, we could distinguish Duane's syndrome from sixth-nerve palsy in a statistically significant manner.
authors.affiliation: Jules Stein Eye Institute, Department of Ophthalmology, UCLA School of Medicine 90024-7001.
authors.forename: M C
authors.initials: MC
authors.lastname: Yang
authors.forename: J B
authors.initials: JB
authors.lastname: Bateman
authors.forename: R D
authors.initials: RD
authors.lastname: Yee
authors.forename: L
authors.initials: L
authors.lastname: Apt
mesh_terms: D000010:Abducens Nerve; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003389:Cranial Nerve Diseases / Q000175:diagnosis; D016002:Discriminant Analysis; D004370:Duane Retraction Syndrome / Q000175:diagnosis*; D004585:Electrooculography; D005133:Eye Movements; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010243:Paralysis / Q000175:diagnosis*; D015203:Reproducibility of Results; D012438:Saccades