title: [Need of updating hepatological nosology].
abstract: The nosological classification of chronic liver disease (CLD) seems to be unsatisfactory when clinical problems are faced such as the liver cirrhosis-diabetes mellitus and the autoimmune diseases-primary biliary cirrhosis (PBC) associations; the concept of PBC as a systemic disease; the multiorgan involvement of chronic active hepatitis. Accordingly, the Authors hypothesize that the present histopathological-based nosology of CLD will be modified as a result of a better understanding of the varied metabolic and immunologic derangements induced by CLD.
authors.affiliation: Divisione di Medicina Generale I, Ospedale civile, Modena.
authors.forename: A
authors.initials: A
authors.lastname: Lonardo
authors.forename: A
authors.initials: A
authors.lastname: Grisendi
authors.forename: M
authors.initials: M
authors.lastname: Pulvirenti
mesh_terms: D000328:Adult; D001327:Autoimmune Diseases / Q000150:complications; D002908:Chronic Disease; D048909:Diabetes Complications; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000150:complications; D008107:Liver Diseases / Q000145:classification* / Q000150:complications / Q000276:immunology