[The recovery of humoral immunity after the long-term action of tritium oxide at different irradiation levels].
Dynamics of recovery of humoral immunity of CBA mice was studied 1, 3, 6 and 12 months after termination of long-term exposure to tritium oxide at various levels of absorbed doses (3, 5 and 9 Gy) and dose rates (3.3, 4.9 and 9.2 cGy.day-1). A severer and more stable residual radiation damage was observed in the department of lymphocyte precursors. A considerable decrease in the content of antibody producers was due to the lymphoid tissue hypoplasia. There was a direct relationship between the immunodeficiency and dose rate and total absorbed dose of beta radiation.
Smirnov
D G
DG
Okatenko
M A
MA
D000818:Animals; D000917:Antibody Formation / Q000276:immunology / Q000528:radiation effects*; D000921:Antibody-Producing Cells / Q000276:immunology / Q000528:radiation effects; D003114:Colony-Forming Units Assay; D004307:Dose-Response Relationship, Radiation; D006412:Hematopoietic Stem Cells / Q000276:immunology / Q000528:radiation effects; D007114:Immunization; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D013154:Spleen / Q000276:immunology / Q000528:radiation effects; D013997:Time Factors; D014316:Tritium / Q000494:pharmacology*; D014867:Water / Q000494:pharmacology*
D014867:Water; D014316:Tritium; C033961:tritium oxide