Lymphocytic hypophysitis with involvement of the cavernous sinus and hypothalamus.
Two cases of lymphocytic hypophysitis are reported, in which hypothalamic involvement causing diabetes insipidus was a prominent clinical feature. In one case, a man had clinical and radiological evidence of the involvement of the cavernous sinus. This represents the second reported case of a man with lymphocytic hypophysitis. A transsphenoidal biopsy established the diagnosis in both cases. Neither the involvement of the cavernous sinus nor permanent diabetes insipidus has been reported previously. A review of the literature is provided.
Nussbaum
C E
CE
Division of Neurological Surgery, University of Rochester Medical Center, New York.
Okawara
S H
SH
Jacobs
L S
LS
D000328:Adult; D002426:Cavernous Sinus / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D003919:Diabetes Insipidus / Q000209:etiology; D005260:Female; D006801:Humans; D007027:Hypothalamic Diseases / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D007249:Inflammation / Q000150:complications / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D008297:Male; D010900:Pituitary Diseases / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D011859:Radiography