[Experimental studies of wound healing in the paranasal sinuses. I. A model of respiratory wounds in the rabbit maxillary sinus].
We present an animal model in rabbits for the investigation of normal wound healing in the paranasal sinuses. The blood and lymphatic stream and the mucociliary pathways are demonstrated on the medial maxillary sinus wall to study the influence on wound geometry. Standardized and circular wounds are created in the same area exposing the underlying bone of the maxillary sinus. Using a computer aided system for 3-D-reconstruction, it can be shown that respiratory wound closure is independent of the stream of blood, lymph or mucus. The circular wound diminishes in size concentrically. The standardized wound model may be suitable for comparison of different therapeutic methods of wound care.
Hosemann
W
W
HNO-Klinik, Universität Erlangen-Nürnberg.
Göde
U
U
Länger
F
F
Röckelein
G
G
Wigand
M E
ME
D000818:Animals; D008196:Lymph / Q000502:physiology; D008208:Lymphatic System / Q000473:pathology; D008443:Maxillary Sinus / Q000098:blood supply / Q000473:pathology* / Q000601:surgery; D009079:Mucociliary Clearance / Q000502:physiology; D009297:Nasal Mucosa / Q000098:blood supply / Q000473:pathology*; D010256:Paranasal Sinuses / Q000098:blood supply / Q000473:pathology* / Q000601:surgery; D011817:Rabbits; D012039:Regional Blood Flow / Q000502:physiology; D014945:Wound Healing / Q000502:physiology*