XLMR genes: update 1990.
We have identified 39 X-linked conditions in which mental retardation seems to be the primary characteristic, although pathogenesis is unknown. These conditions can be subdivided into syndromal and non-syndromal, depending on the existence of a recognizable pattern of minor anomalies and/or malformations, or lack thereof. Seventeen genes have been regionally mapped onto the X chromosome. However, in 14 instances the data were derived from a single family and most lod scores were less than 3.0.
Neri
G
G
Istituto di Genetica Umana A. Gemelli School of Medicine, U.C.S.C., Rome, Italy.
Gurrieri
F
F
Gal
A
A
Lubs
H A
HA
D002874:Chromosome Mapping; D000013:Congenital Abnormalities / Q000235:genetics; D005260:Female; D005819:Genetic Markers; D006801:Humans; D008607:Intellectual Disability / Q000145:classification / Q000235:genetics*; D008297:Male; D014960:X Chromosome
D005819:Genetic Markers