title: Is silicone associated with connective tissue disease?
abstract: Connective tissue diseases have been described in patients who have had silicone augmentation mammoplasty. Several possible mechanisms of pathogenesis are postulated. Although otherwise indistinguishable from other connective tissue disease, these patients may experience improvement or remission following implant removal. Current data suggest that the risk of disease after silicone breast augmentation is less than one percent. A large well-designed epidemiologic study will be needed to confirm this association.
authors.affiliation: University of South Florida College of Medicine, Tampa.
authors.forename: M J
authors.initials: MJ
authors.lastname: Seleznick
authors.forename: P
authors.initials: P
authors.lastname: Martinez-Osuna
authors.forename: L R
authors.initials: LR
authors.lastname: Espinoza
authors.forename: F B
authors.initials: FB
authors.lastname: Vasey
mesh_terms: D000328:Adult; D001940:Breast / Q000601:surgery*; D003240:Connective Tissue Diseases / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D019736:Prostheses and Implants; D012828:Silicones / Q000009:adverse effects*
chemical_list: D012828:Silicones