title: Spontaneous pneumothorax in cystic adenomatoid malformation. Unusual clinical and histologic features.
abstract: Pneumothorax is a rare presentation of congenital cystic adenomatoid malformation (CCAM) in the newborn period and is presumed to be due to resuscitative measures. A previously well three-week-old baby presented with spontaneous tension pneumothorax due to CCAM. In the lung resection specimen, a malformation was seen, which in addition to the histologic changes of CCAM, showed diffuse vascular proliferation in the interstitium and lining of air space by type 2 pneumocytes. We propose that this is a new variant of CCAM rather than one of the classic three types. The unusual clinical manifestation may be related to the unusual histologic features.
authors.affiliation: Division of Chest Medicine, Hospital for Sick Children, Toronto, Canada.
authors.forename: L
authors.initials: L
authors.lastname: Bentur
authors.forename: G
authors.initials: G
authors.lastname: Canny
authors.forename: P
authors.initials: P
authors.lastname: Thorner
authors.forename: R
authors.initials: R
authors.lastname: Superina
authors.forename: P
authors.initials: P
authors.lastname: Babyn
authors.forename: H
authors.initials: H
authors.lastname: Levison
mesh_terms: D015615:Cystic Adenomatoid Malformation of Lung, Congenital / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000473:pathology; D008854:Microscopy, Electron; D011030:Pneumothorax / Q000209:etiology*