title: [Endobronchial drug administration in resuscitation].
abstract: The endobronchial application of drugs is recommended during pharmacological reanimation in lack of venous punction possibility. To find out the quantity of the area of resorption after deep endobronchial instillation twelve human corpses had been intubated and methylen-blue was applicated through the tube. A special application kit with a single use ampule was used. The results showed a very good distribution of 100% or 90% in the bronchi principals dexter and sinister. The bronchi lobaris of the right and the left bronchial tree were reached by the injection with an incidence of more than 70%. This proved distribution of the applicated indicator liquid in a patient in horizontal position (no circulation) allows the statement that during reanimation a sufficient pulmonal surface area is reached in both lungs to guarantee a resorption of the drug.
authors.affiliation: Institut für Anästhesiologie, Universität Würzburg.
authors.forename: P
authors.initials: P
authors.lastname: Sefrin
authors.forename: A
authors.initials: A
authors.lastname: Finkenzeller
mesh_terms: D001980:Bronchi / Q000187:drug effects*; D003131:Combined Modality Therapy; D004837:Epinephrine / Q000008:administration & dosage*; D006323:Heart Arrest / Q000628:therapy*; D006801:Humans; D007277:Injections, Jet; D007442:Intubation, Intratracheal / Q000295:instrumentation; D012151:Resuscitation / Q000379:methods*
chemical_list: D004837:Epinephrine