Histological features in liver biopsy specimens of patients with acute reactivation of chronic type B hepatitis.
The histological features in liver biopsy specimens from seven patients with acute exacerbation of chronic type B hepatitis were analysed. In all the cases typical changes of acute hepatitis were superimposed on signs of chronicity, namely peripheral piecemeal necrosis, plasma cell infiltration and porto-portal bridges, which in three cases contained elastic fibres. Reactivation of silent hepatitis B virus chronic infection should be considered as a possible diagnosis in any patient with histological findings of acute and chronic hepatitis.
Villari
D
D
Dipartimento di Patologia Umana, Policlinico Universitario di Messina, Italy.
Raimondo
G
G
Brancatelli
S
S
Longo
G
G
Rodinò
G
G
Smedile
V
V
D001706:Biopsy; D002908:Chronic Disease; D004279:DNA, Viral / Q000032:analysis; D006509:Hepatitis B / Q000276:immunology / Q000473:pathology* / Q000503:physiopathology; D006512:Hepatitis B Core Antigens / Q000032:analysis; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006515:Hepatitis B virus / Q000235:genetics / Q000302:isolation & purification; D006651:Histocytochemistry; D006801:Humans; D008099:Liver / Q000737:chemistry / Q000382:microbiology / Q000473:pathology*; D009336:Necrosis
D004279:DNA, Viral; D006512:Hepatitis B Core Antigens; D006514:Hepatitis B Surface Antigens