title: Serum-sickness-like illness as a complication after streptokinase therapy for acute myocardial infarction.
abstract: We report a case of serum-sickness-like illness in a 47-year-old patient who received early high-dose intravenous and intracoronary streptokinase following acute myocardial infarction. The picture comprised severe arthralgias, fever, an urticarial rash and marked elevation of circulating immune complexes. This case represents a rare complication of streptokinase therapy.
authors.affiliation: Department of Cardiology, University of Hospital Leiden, The Netherlands.
authors.forename: D H
authors.initials: DH
authors.lastname: Schweitzer
authors.forename: E E
authors.initials: EE
authors.lastname: van der Wall
authors.forename: H A
authors.initials: HA
authors.lastname: Bosker
authors.forename: E
authors.initials: E
authors.lastname: Scheffer
authors.forename: J D
authors.initials: JD
authors.lastname: Macfarlane
mesh_terms: D000936:Antigen-Antibody Complex / Q000032:analysis; D001706:Biopsy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy*; D012713:Serum Sickness / Q000139:chemically induced* / Q000473:pathology; D012867:Skin / Q000473:pathology; D013300:Streptokinase / Q000009:adverse effects* / Q000627:therapeutic use; D015912:Thrombolytic Therapy / Q000009:adverse effects*
chemical_list: D000936:Antigen-Antibody Complex; D013300:Streptokinase