A prospective assessment of opiate addiction treatment protocols for inpatients with HIV-related syndromes.
A sample of 114 intravenous drug abusers hospitalized for HIV-spectrum diseases, was allowed to choose between methadone maintenance, partial or complete withdrawal as inpatient programs and was reassessed 4 days after discharge. One third of the patients had relapsed into heroin abuse. Rates of early relapse were significantly lower in the partial withdrawal group and higher in the methadone maintenance group. Patients with longer hospitalization and more severe HIV-related syndromes were particularly at risk of early relapse. Also, 45 former intravenous drug abusers were reassessed. Relapses were even more frequent than among active abusers, especially if the drug-free period before admission had been shorter than 1 year.
Persico
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Drug Addiction and Alcoholism Unit, Catholic University of the Sacred Heart, Rome, Italy.
Di Giannantonio
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Tempesta
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D000328:Adult; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000150:complications / Q000523:psychology* / Q000635:transmission; D006556:Heroin Dependence / Q000150:complications / Q000534:rehabilitation*; D006760:Hospitalization; D006801:Humans; D008297:Male; D008691:Methadone / Q000627:therapeutic use; D009894:Opportunistic Infections / Q000150:complications / Q000523:psychology / Q000635:transmission; D011446:Prospective Studies; D011613:Psychotherapy; D011619:Psychotropic Drugs / Q000627:therapeutic use; D012008:Recurrence; D015819:Substance Abuse, Intravenous / Q000150:complications / Q000534:rehabilitation*
D011619:Psychotropic Drugs; D008691:Methadone