title: Peritonitis complicating continuous ambulatory peritoneal dialysis in Nottingham 1983-1988.
abstract: During the period 1983-1988 the incidence of peritonitis in patients undergoing continuous ambulatory peritoneal dialysis (CAPD) in Nottingham fell from 2.0 to 1.2 episodes/patient/year. Cefuroxime, given intraperitoneally for 10 days, as recommended in published guidelines, failed to cure 35% of episodes of peritonitis, although only 7% of the pathogens responsible for these episodes were resistant in vitro. Cefuroxime is probably no longer appropriate as first line treatment of CAPD peritonitis.
authors.affiliation: Department of Microbial Diseases, City Hospital, Nottingham.
authors.forename: M H
authors.initials: MH
authors.lastname: Wilcox
authors.forename: R G
authors.initials: RG
authors.lastname: Finch
authors.forename: R P
authors.initials: RP
authors.lastname: Burden
authors.forename: A G
authors.initials: AG
authors.lastname: Morgan
mesh_terms: D001419:Bacteria / Q000187:drug effects; D002444:Cefuroxime / Q000627:therapeutic use; D004352:Drug Resistance, Microbial; D006801:Humans; D015994:Incidence; D008826:Microbial Sensitivity Tests; D010531:Peritoneal Dialysis, Continuous Ambulatory; D010538:Peritonitis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D006113:United Kingdom / Q000453:epidemiology
chemical_list: D002444:Cefuroxime