title: Decreased vasoactive intestinal polypeptide (VIP) level in cerebrospinal fluid from diabetic patients with neuropathy.
abstract: The concentration of vasoactive intestinal polypeptide (VIP) was measured in cerebrospinal fluid (CSF) obtained from diabetic patients with neuropathy and their age-matched control subjects. VIP level in CSF from diabetic patients was significantly decreased as compared with that from the controls (12.9 +/- 3.1 pg/ml vs. 35.4 +/- 3.3 pg/ml, p less than 0.01). Decreased VIP level in CSF may relate with diabetic neuropathy in particular sexual dysfunction.
authors.affiliation: Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka.
authors.forename: F
authors.initials: F
authors.lastname: Umeda
authors.forename: K
authors.initials: K
authors.lastname: Noda
authors.forename: H
authors.initials: H
authors.lastname: Ono
authors.forename: Y
authors.initials: Y
authors.lastname: Chijiiwa
authors.forename: H
authors.initials: H
authors.lastname: Nawata
mesh_terms: D000328:Adult; D003929:Diabetic Neuropathies / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007006:Hypogonadism / Q000175:diagnosis / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D014660:Vasoactive Intestinal Peptide / Q000134:cerebrospinal fluid*
chemical_list: D014660:Vasoactive Intestinal Peptide