title: The early and long-term results of surgery for coarctation of the aorta in the 1st year of life.
abstract: The cases of 110 infants less than 1 year of age, who had surgical repair for coarctation of the aorta between June 1974 and February 1988, were analysed. Three groups of patients were identified. In group 1 there were 39 patients with isolated coarctation. In group 2 there were 25 infants with additional ventricular septal defects (VSD), while in group 3 there were 46 infants with other associated congenital cardiac defects. Repair was performed using the subclavian flap aortoplasty (SFA) procedure in 83 patients, resection with end-to-end anastomosis (EEA) in 23, patch aortoplasty in 3 and Goretex tube bypass in 1. Twenty-eight patients had simultaneous pulmonary artery banding and one concomitant closure of the VSD. The overall early mortality rate was 8.2% (5.1% in group 1, 0% in group 2, and 15.2% in group 3). Age at operation (under 1 month, p = 0.04) and other associated cardiac anomalies (p = 0.03) increased early mortality significantly. There were 11 late deaths (10.8%) among 101 patients followed from 1 to 15 years (mean 5.3 years). Twelve patients underwent further surgery for recoarctation, eight of them within 11 months. A further 11 patients currently have a Doppler gradient across their coarctation site of more than 20 mmHg, but have not undergone further surgery to the coarctation repair site.
authors.affiliation: Wessex Cardiothoracic Centre, Southampton General Hospital, Shirley, UK.
authors.forename: C P
authors.initials: CP
authors.lastname: Shrivastava
authors.forename: J L
authors.initials: JL
authors.lastname: Monro
authors.forename: D F
authors.initials: DF
authors.lastname: Shore
authors.forename: R K
authors.initials: RK
authors.lastname: Lamb
authors.forename: G R
authors.initials: GR
authors.lastname: Sutherland
authors.forename: L V
authors.initials: LV
authors.lastname: Fong
authors.forename: B R
authors.initials: BR
authors.lastname: Keeton
mesh_terms: D000714:Anastomosis, Surgical; D001011:Aorta / Q000601:surgery; D001017:Aortic Coarctation / Q000150:complications / Q000401:mortality / Q000601:surgery*; D001807:Blood Vessel Prosthesis; D005260:Female; D005500:Follow-Up Studies; D006330:Heart Defects, Congenital / Q000150:complications; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011138:Polytetrafluoroethylene; D011651:Pulmonary Artery / Q000601:surgery; D012008:Recurrence; D012086:Reoperation; D013348:Subclavian Artery / Q000637:transplantation; D013524:Surgical Flaps / Q000379:methods; D015996:Survival Rate
chemical_list: D011138:Polytetrafluoroethylene