Chronic atrophic oral candidiasis among patients with diabetes mellitus--role of secretor status.
Non-diabetic individuals who are non-secretors of blood group antigens are prone to superficial infections by Candida albicans. In this study, 216 patients with diabetes mellitus who were denture wearers were examined for the presence or absence of denture stomatitis. There was an overall trend for non-secretors to be prone to denture stomatitis compared with secretors. Stepwise linear discriminant analysis was used to dissect the contribution of secretor status and other variables to the development of the disease. Secretor status was found to be a contributory factor among patients with non-insulin dependent diabetes but not among those with insulin-dependent diabetes. The possible reasons for this are discussed.
Aly
F Z
FZ
Department of Medical Microbiology, University of Edinburgh Medical School.
Blackwell
C C
CC
MacKenzie
D A
DA
Weir
D M
DM
Elton
R A
RA
Cumming
C G
CG
Sofaer
J A
JA
Clarke
B F
BF
D000017:ABO Blood-Group System; D000367:Age Factors; D001786:Blood Glucose / Q000032:analysis; D001789:Blood Group Antigens; D002180:Candidiasis, Oral / Q000209:etiology*; D002908:Chronic Disease; D003778:Dentures; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D006801:Humans; D007983:Lewis Blood Group Antigens; D012737:Sex Factors; D013282:Stomatitis, Denture / Q000209:etiology*
D000017:ABO Blood-Group System; D001786:Blood Glucose; D001789:Blood Group Antigens; D007983:Lewis Blood Group Antigens