title: BIPP induced methaemoglobinaemia.
abstract: Bismuth subnitrate, one of the constituents of BIPP is known to cause methaemoglobinaemia. Ten patients had blood estimations for methaemoglobin levels before and after nasal packing with BIPP impregnated gauze. Only one patient exhibited abnormal levels of methaemoglobin and this was most probably the result of the large quantity of BIPP used. It is unlikely that significant methaemoglobinaemia occurs during the routine use of BIPP in the nose.
authors.affiliation: Department of Otlaryngology, Dudley Road Hospital, Birmingham.
authors.forename: A
authors.initials: A
authors.lastname: Nigam
authors.forename: J
authors.initials: J
authors.lastname: Ruddy
authors.forename: P E
authors.initials: PE
authors.lastname: Robin
mesh_terms: D000281:Administration, Intranasal; D000293:Adolescent; D001458:Bandages; D001729:Bismuth / Q000008:administration & dosage / Q000009:adverse effects*; D004338:Drug Combinations; D004844:Epistaxis / Q000628:therapy; D006801:Humans; D006847:Hydrocarbons, Iodinated / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D008708:Methemoglobinemia / Q000139:chemically induced*; D009666:Nose / Q000601:surgery
chemical_list: D004338:Drug Combinations; D006847:Hydrocarbons, Iodinated; C045757:bismuth iodoform paraffin paste; D001729:Bismuth