title: Primary surgical therapy of ovarian cancer: how much and when.
abstract: From July 1975 through December 1985, 328 patients with ovarian malignancies were treated. Of these, 302 had epithelial invasive malignancies and constitute the study group. The impact of the operative procedure, findings, and subsequent treatment is evaluated. Patients who underwent extensive debulking procedures such as bowel resection and peritoneal stripping did not have improved survival compared with those patients who did not undergo these procedures and yet had residual disease remaining (P = 0.7 and P = 0.34). Reoperating patients felt to be unresectable at the time of referral did not increase survival over reoperating patients after an attempt at chemotherapeutic reduction (P = 0.34).
authors.affiliation: Division of Gynecologic Oncology, University of Alabama, Birmingham 35294.
authors.forename: M E
authors.initials: ME
authors.lastname: Potter
authors.forename: E E
authors.initials: EE
authors.lastname: Partridge
authors.forename: K D
authors.initials: KD
authors.lastname: Hatch
authors.forename: S J
authors.initials: SJ
authors.lastname: Soong
authors.forename: J M
authors.initials: JM
authors.lastname: Austin
authors.forename: H M
authors.initials: HM
authors.lastname: Shingleton
mesh_terms: D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000401:mortality / Q000601:surgery*; D012086:Reoperation