title: A field evaluation of treatment with febantel for the control of Toxocara canis in pups.
abstract: The faecal egg count depression (FECD) of febantel (Rintal vet. 100 mg tablets, Bayer AG, Veterinär-Bereich, Leverkusen), against Toxocara canis was tested in suckling pups treated at 2 weeks of age. The dose rate was 30 mg kg-1 body weight given orally, once every 12 h, three times. The effect of a further treatment of 6- and 12-week-old pups on excreted eggs was also evaluated. The FECD of 6-week-old pups was 100%. However, some of the 12- and 17-week-old pups had low eggs per gram (epg) values indicating that shorter intervals between the treatments should have been used in order to minimize the risk of spreading T. canis eggs. The control pups of the first treatment group were untreated litter mates. They were treated when 4 weeks old and then followed a similar regimen to the experimental animals. At 6 weeks of age, their FECD was 100%, but low epg values were observed among 12- and 17-week-old pups, similar to the test group.
authors.affiliation: Department of Veterinary Microbiology, College of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala.
authors.forename: D A
authors.initials: DA
authors.lastname: Christensson
authors.forename: H
authors.initials: H
authors.lastname: Raue
authors.forename: S
authors.initials: S
authors.lastname: Bernstad
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D004283:Dog Diseases / Q000517:prevention & control*; D004285:Dogs; D005243:Feces / Q000469:parasitology; D005260:Female; D006146:Guanidines / Q000627:therapeutic use*; D008297:Male; D010270:Parasite Egg Count / Q000662:veterinary; D011897:Random Allocation; D014120:Toxocariasis / Q000517:prevention & control / Q000662:veterinary*
chemical_list: D000871:Anthelmintics; D006146:Guanidines; C017309:febantel