title: Special considerations for research with pharmacologic agents.
abstract: As physical medicine and rehabilitation becomes more and more complicated, the medical rehabilitation research teams are often bewildered by the sweeping changes occurring in the application of therapeutic drugs for rehabilitation. Society, through the instrument of governmental regulations, dictates that all new treatments must be efficacious before "release."
authors.affiliation: Chedoke Rehabilitation Centre, Chedoke-McMaster Hospitals and McMaster University, Hamilton, Ontario, Canada.
authors.forename: J V
authors.initials: JV
authors.lastname: Basmajian
mesh_terms: D000818:Animals; D003620:Dantrolene / Q000009:adverse effects / Q000627:therapeutic use; D004341:Drug Evaluation / Q000379:methods; D006801:Humans; D009128:Muscle Spasticity / Q000188:drug therapy; D010600:Pharmacology; D010919:Placebos; D012106:Research; D012107:Research Design / Q000592:standards; D012307:Risk Factors; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D010919:Placebos; D003620:Dantrolene