title: Direct immunofluorescence testing of haired skin, nasal planum, and footpads of clinically normal woodchuck hepatitis virus-infected and non-infected woodchucks.
abstract: The purpose of this study was to determine the frequency of immunoreactant deposition in the skin, footpad, and nasal planum of 10 clinically normal, non WHV-infected woodchucks. The second part of the study investigated the frequency of immunoreactant deposition at the same sites in clinically normal, WHV-infected woodchucks, and compared these results with those reported in humans. Direct immunofluorescence testing of the haired skin, footpad, and nasal planum of all normal and 9 of the 10 WHV-infected woodchucks was negative. The footpad of 1 WHV-infected woodchuck revealed immunoreactant deposition in the walls of the superficial dermal blood vessels.
authors.affiliation: Department of Clinical Sciences, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853.
authors.forename: R
authors.initials: R
authors.lastname: Panich
authors.forename: D W
authors.initials: DW
authors.lastname: Scott
authors.forename: C A
authors.initials: CA
authors.lastname: Smith
authors.forename: B C
authors.initials: BC
authors.lastname: Tennant
mesh_terms: D000818:Animals; D005260:Female; D005455:Fluorescent Antibody Technique; D005528:Foot; D006197:Hair; D015613:Hepadnaviridae; D006524:Hepatitis, Viral, Animal / Q000276:immunology*; D007136:Immunoglobulins / Q000032:analysis*; D008297:Male; D008392:Marmota / Q000276:immunology*; D009666:Nose; D012867:Skin / Q000276:immunology*
chemical_list: D007136:Immunoglobulins