The use of fluoxetine in an adolescent with Prader-Willi syndrome.
A case of a 17-year-old female with a diagnosis of Prader-Willi syndrome, including mild mental retardation, compulsive eating with gross obesity and trichotillomania with trichophagia, is presented. She has a long history of multiple cognitive, behavioral, and psychopharmacological treatments, including several inpatient hospitalizations that had produced only limited success. With the introduction of a fluoxetine trial, she demonstrated a marked improvement in weight control and a moderate improvement in hair pulling over a 6-month period of observation.
Dech
B
B
Department of Psychiatry and Behavioral Sciences, Children's Hospital, Denver, Colorado 80218-1088.
Budow
L
L
D000293:Adolescent; D001521:Behavior Therapy; D001068:Feeding and Eating Disorders / Q000188:drug therapy; D005260:Female; D005473:Fluoxetine / Q000627:therapeutic use*; D006760:Hospitalization; D006801:Humans; D008607:Intellectual Disability / Q000188:drug therapy; D009767:Obesity, Morbid / Q000150:complications / Q000188:drug therapy / Q000628:therapy; D011218:Prader-Willi Syndrome / Q000150:complications / Q000188:drug therapy*; D014256:Trichotillomania / Q000188:drug therapy
D005473:Fluoxetine