Carcinoma of the vulva with sarcomatoid features: a case report with immunohistochemical study.
A tumor of the vulva with sarcomatoid features was studied by immunocytochemistry to characterize the phenotype of the spindle-shaped and giant cells. Sarcomatoid-looking cells were positive for intermediate filament keratin polypeptides of stratified epithelium. These results favor histogenesis of the sarcomatoid-looking cells from a metaplastic alteration of the malignant squamous component.
Santeusanio
G
G
Cattedra di Anatomia e Istologia Patologica, II Università di Roma, Tor Vergata, Italy.
Schiaroli
S
S
Anemona
L
L
Sesti
F
F
Valli
E
E
Piccione
E
E
Spagnoli
L G
LG
D000368:Aged; D002277:Carcinoma / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D012509:Sarcoma / Q000473:pathology*; D014846:Vulvar Neoplasms / Q000378:metabolism / Q000473:pathology*