[Diurnal enuresis in childhood is effectively treated with terodiline].
Efficacy and tolerance of the anticholinergic calcium antagonist, terodiline (Mictrol), were investigated in a placebo-controlled double-blind cross-over study of 42 children with diurnal enuresis. At a daily dosage of 25 mg, terodiline was well tolerated and, as compared with placebo, resulted in a statistically significant reduction in the daily frequency of wetting. Thus the findings show terodiline to be effective in the treatment of diurnal enuresis, an added advantage being the low incidence of side effects. A full report in English is given in Scand J Prim Health Care 1988; 6:119-24.
Elmér
M
M
Distriktsöverläkare, vårdcentralen S:t Lars, Lund.
Adolfsson
T
T
Nørgaard
J P
JP
Djurhuus
J C
JC
D000293:Adolescent; D002082:Butylamines / Q000008:administration & dosage / Q000627:therapeutic use*; D002121:Calcium Channel Blockers / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004311:Double-Blind Method; D004341:Drug Evaluation; D004775:Enuresis / Q000188:drug therapy*; D006801:Humans
D002082:Butylamines; D002121:Calcium Channel Blockers; C010637:terodiline