title: Hyperthyroxinemia in major affective disorders.
abstract: Ninety-nine patients fulfilling DSM-III criteria for primary major affective disorder, either bipolar or unipolar, were studied. A 12% prevalence of elevated thyroxine levels was found. Three of the 12 hyperthyroxinemia patients also had elevated free thyroxine index. No statistically significant difference in response to antidepressant treatment was observed between the hyperthyroxinemia group and the normal serum thyroxine group.
authors.affiliation: Department of Psychiatry, St. Michael's Hospital, Toronto, Ontario, Canada.
authors.forename: R
authors.initials: R
authors.lastname: Styra
authors.forename: R
authors.initials: R
authors.lastname: Joffe
authors.forename: W
authors.initials: W
authors.lastname: Singer
mesh_terms: D000328:Adult; D000928:Antidepressive Agents / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000188:drug therapy / Q000209:etiology* / Q000523:psychology; D003866:Depressive Disorder / Q000188:drug therapy / Q000209:etiology* / Q000523:psychology; D005260:Female; D006801:Humans; D006981:Hyperthyroxinemia / Q000150:complications* / Q000188:drug therapy / Q000523:psychology; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000188:drug therapy / Q000209:etiology* / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D013960:Thyroid Function Tests; D013974:Thyroxine / Q000097:blood
chemical_list: D000928:Antidepressive Agents; D013974:Thyroxine