Hypercalcaemia and the synthesis of interleukin-1 by an ameloblastoma.
A case of hypercalcaemia secondary to a long-standing solitary ameloblastoma is presented with evidence to suggest that the raised plasma calcium was the result of the secretion of interleukin-1 and a parathyroid hormone-like substances by the tumour. The aetiology of humoral hypercalcaemia of malignancy is discussed in relation to the role played by these substances.
Macpherson
D W
DW
Joint Department of Maxillofacial Surgery and Oral Medicine, Eastman Dental Hospital, London.
Hopper
C
C
Meghji
S
S
D000564:Ameloblastoma / Q000150:complications* / Q000503:physiopathology; D001862:Bone Resorption / Q000209:etiology*; D006801:Humans; D006934:Hypercalcemia / Q000097:blood / Q000209:etiology*; D007378:Interleukins / Q000096:biosynthesis*; D008297:Male; D008339:Mandibular Neoplasms / Q000150:complications* / Q000503:physiopathology; D008875:Middle Aged
D007378:Interleukins