Correction of hypophosphatemia in patients on hemodialysis using a calcium-free dialysate with added phosphate.
Three patients on long term hemodialysis were found to be hypophosphatemic. They were treated using a calcium-free dialysate to which phosphate was added to give a final concentration of 1 or 2 mmol/l. All corrected their low phosphates. Hypocalcemia developed in two patients when the calcium infusion rate was 15 ml/hour of 10% CaCl2. It is recommended that this should be increased to 20 ml/hour. Under these circumstances, correction of hypophosphatemia is possible with the transfer of approximately 30-35 mmol phosphate over a four-hour dialysis.
Kaye
M
M
Division of Nephrology, Montreal General Hospital, Quebec, Canada.
Vasilevsky
M
M
Barber
E
E
D000328:Adult; D002118:Calcium; D005260:Female; D015312:Hemodialysis Solutions; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010710:Phosphates / Q000097:blood* / Q000627:therapeutic use; D006435:Renal Dialysis; D013997:Time Factors
D015312:Hemodialysis Solutions; D010710:Phosphates; D002118:Calcium