title: [Intravaginal PgE2 administration for inducing labor in premature rupture of fetal membranes].
abstract: In a prospective study, 121 patients with spontaneous rupture of the membranes of greater than 6 hours duration and unfavourable Bishop-Score (less than 6) were stimulated with 3 mg vaginal prostaglandin-E2-tablets. All patients started labour. Only one patient had a hyperstimulation which was corrected with betamimetics. There were no systemic side effects. Almost 90% of the women delivered on the first day. The rate of the Caesarean sections was low. There was no case of intraamniotic infection; the foetal outcome was good. In conclusion, vaginal prostaglandin-E2-tablets are safe to use in spontaneous rupture of the membranes.
authors.affiliation: Gebh.-Gyn. Klinik, Kantonsspital Liestal.
authors.forename: D
authors.initials: D
authors.lastname: Schaetti
authors.forename: D
authors.initials: D
authors.lastname: Blumer
authors.forename: N
authors.initials: N
authors.lastname: Dutar
authors.forename: R
authors.initials: R
authors.lastname: Gaudenz
authors.forename: W
authors.initials: W
authors.lastname: Hugentobler
mesh_terms: D000282:Administration, Intravaginal; D002585:Cesarean Section; D015232:Dinoprostone / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000628:therapy*; D005323:Fetal Monitoring; D006801:Humans; D007231:Infant, Newborn; D007751:Labor, Induced / Q000379:methods*; D011247:Pregnancy
chemical_list: D015232:Dinoprostone