[The immunohistochemical study of lymphocyte subpopulations in benign and malignant epithelial tumors of the large intestine].
Immunohistochemical methods using monoclonal antibodies were employed to semiquantitatively assess levels of B-lymphocytes and T-lymphocyte subpopulations (suppressors and helpers) in 12 moderately differentiated adenocarcinomas, five tubular adenomas, three villous tumors and in microscopically unaltered large bowel tissue. Helper/suppressor ratio was the most important characteristics of lymphocyte infiltrates. The parameter was significantly lower in adenocarcinoma as compared to tubular adenoma and microscopically unaltered mucosa.
Bandaletova
T Iu
TIu
D000230:Adenocarcinoma / Q000378:metabolism; D000236:Adenoma / Q000378:metabolism; D000911:Antibodies, Monoclonal; D002277:Carcinoma / Q000378:metabolism*; D006801:Humans; D007150:Immunohistochemistry; D007414:Intestinal Neoplasms / Q000378:metabolism*; D007420:Intestine, Large / Q000378:metabolism; D007958:Leukocyte Count; D016131:Lymphocyte Subsets / Q000276:immunology / Q000378:metabolism*
D000911:Antibodies, Monoclonal