Cellular follicular cyst of the ovary: fluid cytology mimicking malignancy.
We report three ovarian cysts studied by aspiration cytology. The fluids obtained were highly cellular, with numerous groups of atypical cells featuring a high nuclear-cytoplasmic ratio, nuclear hyperchromasia, and prominent nucleoli. In each case, these features were considered evidence of a low-grade malignant neoplasm. All three patients underwent oophorectomy, which revealed benign follicular cysts. Possible means of resolving the diagnostic dilemma posed by these cellular follicular cysts are discussed.
Stanley
M W
MW
Department of Pathology, Hennepin County Medical Center, Minneapolis, MN 55415.
Horwitz
C A
CA
Frable
W J
WJ
D000328:Adult; D001707:Biopsy, Needle; D002467:Cell Nucleus / Q000473:pathology; D002843:Chromatin / Q000473:pathology; D003581:Cytodiagnosis; D003593:Cytoplasm / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006107:Granulosa Cells / Q000473:pathology; D006801:Humans; D010048:Ovarian Cysts / Q000175:diagnosis* / Q000473:pathology; D010051:Ovarian Neoplasms / Q000175:diagnosis*; D010053:Ovary / Q000473:pathology
D002843:Chromatin