title: Mapping of the gene for human cysteine proteinase inhibitor stefin A, STF1, to chromosome 3cen-q21.
abstract: The gene for the human cysteine proteinase inhibitor stefin A (STF1), alias cystatin A, has been mapped to chromosome 3, using the polymerase chain reaction to specifically amplify the human stefin A sequence in human-hamster hybrid DNA. STF1 is further sublocalized to regions between centromere and 3q21 using a deletion mapping panel for this chromosome. This assignment shows that stefin A is not syntenic with cystatin C which has been localized to chromosome 20.
authors.affiliation: Clinical Neurogenetics Branch, National Institute of Mental Health, Bethesda, Maryland 20892.
authors.forename: W T
authors.initials: WT
authors.lastname: Hsieh
authors.forename: D
authors.initials: D
authors.lastname: Fong
authors.forename: B F
authors.initials: BF
authors.lastname: Sloane
authors.forename: W
authors.initials: W
authors.lastname: Golembieski
authors.forename: D I
authors.initials: DI
authors.lastname: Smith
mesh_terms: D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D002893:Chromosomes, Human, Pair 3; D006224:Cricetinae; D055312:Cystatin A; D015891:Cystatins / Q000235:genetics*; D015853:Cysteine Proteinase Inhibitors; D006801:Humans; D006822:Hybrid Cells; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction
chemical_list: D055312:Cystatin A; D015891:Cystatins; D015853:Cysteine Proteinase Inhibitors; C026407:CSTA protein, human