Steroid-resistant bullous pemphigoid treated with cyclosporin A.
A 70-year-old woman with steroid-resistant bullous pemphigoid, severe osteoporosis, and several crush fractures was given cyclosporin A at a dose of 5 mg/kg/day. Considerable improvement was evident within 4 weeks, and control has been maintained over a period of 14 months allowing reduction of her steroid dose to 4 mg on alternate days.
Curley
R K
RK
Department of Dermatology, St Helier Hospital, Carshalton, Surrey, UK.
Holden
C A
CA
D000368:Aged; D003524:Cyclosporins / Q000627:therapeutic use*; D004351:Drug Resistance; D005260:Female; D006801:Humans; D010024:Osteoporosis / Q000150:complications; D010391:Pemphigoid, Bullous / Q000150:complications / Q000188:drug therapy*; D011239:Prednisolone / Q000627:therapeutic use; D016103:Spinal Fractures / Q000150:complications
D003524:Cyclosporins; D011239:Prednisolone