title: [Acute leukemia successfully treated with natural interferon-alpha].
abstract: Natural interferon-alpha (IFN-alpha) alone was administered to a 42-year-old man with acute leukemia, whose bone marrow revealed hypocellularity (NCC = 6 X 10(4)/microliters) and a 50% increase in blasts. Initial chemotherapy regimens, including BHAC-DMP or low dose Ara-C were ineffective. One month after starting nIFN-alpha therapy, the blasts in his bone marrow decreased below 3% and peripheral blood cell counts became normal. He has been in remission for at least 7 months.
authors.affiliation: First Department of Internal Medicine, Faculty of Medicine, University of Tokyo.
authors.forename: K
authors.initials: K
authors.lastname: Moriya
authors.forename: N
authors.initials: N
authors.lastname: Miura
authors.forename: S
authors.initials: S
authors.lastname: Sunaga
authors.forename: R
authors.initials: R
authors.lastname: Horie
authors.forename: K
authors.initials: K
authors.lastname: Aoki
authors.forename: Y
authors.initials: Y
authors.lastname: Yatomi
authors.forename: A
authors.initials: A
authors.lastname: Yoneyama
authors.forename: M
authors.initials: M
authors.lastname: Higashihara
authors.forename: A
authors.initials: A
authors.lastname: Tanabe
authors.forename: K
authors.initials: K
authors.lastname: Nakahara
mesh_terms: D000208:Acute Disease; D000328:Adult; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use*; D007938:Leukemia / Q000628:therapy*; D008297:Male
chemical_list: D007370:Interferon Type I