DNA analysis of neoplasia: an introduction for the family physician.
Pathologic evaluation of a neoplastic process has traditionally consisted of microscopic examination of a stained section of tissue. Although this method is generally reliable when performed by an experienced pathologist, the morphologic features of a lesion may not consistently predict biologic behavior. The DNA content of tumors can be studied with a flow cytometer to help determine the prognosis and risk of tumor recurrence. DNA analysis of a neoplasm may provide the clinician with important prognostic information and, at some future date, may help direct chemotherapy or other treatment protocols.
Kotylo
P K
PK
Indiana University School of Medicine, Indianapolis.
D000328:Adult; D000782:Aneuploidy; D001943:Breast Neoplasms / Q000235:genetics; D002648:Child; D004273:DNA, Neoplasm / Q000032:analysis*; D004171:Diploidy; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D009369:Neoplasms / Q000235:genetics*; D011379:Prognosis
D004273:DNA, Neoplasm