title: Evaluation of hemostatic defects secondary to vascular tumors in dogs: 11 cases (1983-1988).
abstract: Two populations of dogs with cutaneous hemangiomas and hemangiosarcomas were evaluated retrospectively. One population consisted of 96 dogs seen at the Veterinary Medical Teaching Hospital at the University of California, Davis. The second population consisted of 116 dogs that had skin biopsy specimens submitted to a private veterinary diagnostic laboratory for histologic diagnosis. Nine dogs from the teaching hospital and 2 dogs, from which samples had been submitted to the veterinary diagnostic laboratory, developed hemostatic defects in association with the tumors. Hemostatic defects included hemorrhage directly from the tumor, thrombocytopenia, hypofibrinogenemia, and findings associated with disseminated intravascular coagulation. Because bleeding during surgery can develop in animals with hemostatic defects, dogs with one or more tumors suspected of being vascular in origin should have platelet numbers and hemostatic analytes evaluated prior to surgery, especially if petechiae or ecchymoses are evident.
authors.affiliation: Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman 99164.
authors.forename: A M
authors.initials: AM
authors.lastname: Hargis
authors.forename: B F
authors.initials: BF
authors.lastname: Feldman
mesh_terms: D000740:Anemia / Q000209:etiology / Q000662:veterinary; D000818:Animals; D001778:Blood Coagulation Disorders / Q000209:etiology / Q000662:veterinary; D001947:Breeding; D004211:Disseminated Intravascular Coagulation / Q000209:etiology / Q000662:veterinary; D004283:Dog Diseases / Q000097:blood*; D004285:Dogs; D005340:Fibrinogen / Q000032:analysis; D005500:Follow-Up Studies; D006391:Hemangioma / Q000097:blood / Q000150:complications / Q000662:veterinary*; D006394:Hemangiosarcoma / Q000097:blood / Q000150:complications / Q000662:veterinary*; D006470:Hemorrhage / Q000209:etiology / Q000662:veterinary; D006487:Hemostasis; D010314:Partial Thromboplastin Time / Q000662:veterinary; D011517:Prothrombin Time / Q000662:veterinary; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000097:blood / Q000150:complications / Q000662:veterinary*; D013921:Thrombocytopenia / Q000209:etiology / Q000662:veterinary
chemical_list: D005340:Fibrinogen