title: Neuroleptic malignant syndrome and Escherichia coli urosepsis.
abstract: Neuroleptic malignant syndrome is a rare but potentially life-threatening reaction to neuroleptic drugs. The syndrome develops rapidly, and may occur at the initiation of neuroleptic therapy or after long-term use; its pathogenesis is unclear. The signs and symptoms associated with the syndrome are hyperpyrexia, extreme muscle rigidity, an altered level of consciousness, and autonomic dysfunction. We describe a case of neuroleptic malignant syndrome in a patient who had Escherichia coli urosepsis caused by thioridazine.
authors.affiliation: Department of Medicine, Winthrop-University Hospital, Mineola, NY 11501.
authors.forename: M Q
authors.initials: MQ
authors.lastname: Teglia
authors.forename: T T
authors.initials: TT
authors.lastname: Hopkins
authors.forename: B A
authors.initials: BA
authors.lastname: Cunha
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004927:Escherichia coli Infections / Q000150:complications*; D006801:Humans; D015994:Incidence; D008297:Male; D009459:Neuroleptic Malignant Syndrome / Q000150:complications* / Q000453:epidemiology; D013881:Thioridazine / Q000009:adverse effects*; D014552:Urinary Tract Infections / Q000150:complications / Q000382:microbiology*
chemical_list: D013881:Thioridazine