title: Gastrointestinal complications in 4473 patients who underwent cardiopulmonary bypass surgery.
abstract: Thirty-nine gastrointestinal complications occurred in 35 of 4473 patients (0.78 per cent) who underwent surgery involving cardiopulmonary bypass during an 8-year period. The mortality rate when one of these complications occurred was 22 (63 per cent) representing 11.5 per cent of the 191 deaths from all causes in the series. The relative risk of developing a gastrointestinal complication was 1:249 when the heart was not opened, 1:66 when it was and 1:5 after cardiac transplantation. Gastrointestinal bleeding (n = 20) was the most common complication of whom nine (45 per cent) died, followed by intestinal infarction (n = 12) with eight (67 per cent) deaths and acute pancreatitis (n = 6) all of whom died. There was one death after surgery for gastrointestinal bleeding (n = 7). No patient survived bowel infarction without operation but resection was possible in five of the eight who underwent surgery, four of whom survived. The results demonstrate that surgical intervention is not associated with undue mortality but inappropriate conservative therapy is poorly tolerated in this high-risk group.
authors.affiliation: South West Thames Regional, Cardiothoracic Unit, St. George's Hospital, London, UK.
authors.forename: S P
authors.initials: SP
authors.lastname: Huddy
authors.forename: W P
authors.initials: WP
authors.lastname: Joyce
authors.forename: J R
authors.initials: JR
authors.lastname: Pepper
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology; D002315:Cardiopulmonary Bypass / Q000009:adverse effects* / Q000401:mortality; D005260:Female; D005767:Gastrointestinal Diseases / Q000209:etiology*; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000401:mortality; D006801:Humans; D007422:Intestines / Q000098:blood supply; D007511:Ischemia / Q000209:etiology; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000209:etiology; D012189:Retrospective Studies