Severe hypertension with segmental renal infarction following surgical removal of a retroperitoneal malignant hemangiopericytoma: a case report.
Severe hypertension developed in a fifty-five year-old woman after surgical removal of a retroperitoneal tumor, when the renal artery was injured. Renal arteriography after the surgery demonstrated a segmental infarction of the right kidney. A close relationship between activation of the renin-angiotensin system and the development of severe hypertension was observed. Satisfactory control of blood pressure concomitant with reduction of plasma renin activity was achieved by a combination of an angiotensin-converting anzyme inhibitor, beta-blocking agent, and calcium-entry blocker. The mechanism of activation of the renin-angiotensin system in renal infarction is discussed.
Matsumura
K
K
Third Department of Internal Medicine, Faculty of Medicine, University of Ryukyus, Okinawa, Japan.
Muratani
H
H
Kinjou
K
K
Kimura
Y
Y
Eto
T
T
Fukiyama
K
K
Kusaba
A
A
D005260:Female; D006393:Hemangiopericytoma / Q000601:surgery*; D006801:Humans; D006973:Hypertension / Q000209:etiology* / Q000503:physiopathology; D007238:Infarction / Q000209:etiology*; D007668:Kidney / Q000098:blood supply*; D008875:Middle Aged; D011183:Postoperative Complications; D012077:Renal Artery / Q000293:injuries*; D012084:Renin-Angiotensin System / Q000502:physiology; D012186:Retroperitoneal Neoplasms / Q000601:surgery*