High mebendazole doses in pulmonary and hepatic hydatid disease.
Thirty nine children with 71 hydatid cysts were given mebendazole orally in a dose of 100-200 mg/kg/day for 12 weeks and were followed up for a mean (SD) of 63 (24) months. Twenty children (three of them after a second course) were cured and another two avoided at least one operation. No serious side effects of the drug were observed.
Messaritakis
J
J
First Department of Paediatrics, Athens University School of Medicine, Aghia Sophia, Children's Hospital, Greece.
Psychou
P
P
Nicolaidou
P
P
Karpathios
T
T
Syriopoulou
B
B
Fretzayas
A
A
Krikos
F
F
Matsaniotis
N
N
D000284:Administration, Oral; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D004443:Echinococcosis / Q000188:drug therapy*; D004444:Echinococcosis, Hepatic / Q000188:drug therapy; D004445:Echinococcosis, Pulmonary / Q000188:drug therapy; D005260:Female; D006801:Humans; D008297:Male; D008463:Mebendazole / Q000008:administration & dosage* / Q000627:therapeutic use
D008463:Mebendazole