title: Effect of challenge with Candida albicans strains with different levels of virulence on plasma proteins in burned mice.
abstract: Immunoglobulin G, immunoglobulin A, transferrin, and fibrinogen were measured by radial immunodiffusion in plasma samples from burned versus unburned mice challenged with high-virulence Candida albicans MY 1044 or its low-virulence mutant, MY 1049. Early decreases in these proteins were found after burn and/or MY 1044 but not MY 1049 challenge. These decreases may contribute to increased susceptibility of mice that were burned and challenged by MY 1044 to lethal candidiasis.
authors.affiliation: Shriners Burns Institute, Cincinnati, Ohio.
authors.forename: A N
authors.initials: AN
authors.lastname: Neely
authors.forename: C M
authors.initials: CM
authors.lastname: Childress
authors.forename: I A
authors.initials: IA
authors.lastname: Holder
mesh_terms: D000818:Animals; D001798:Blood Proteins / Q000032:analysis*; D002056:Burns / Q000097:blood*; D002176:Candida albicans / Q000472:pathogenicity*; D005340:Fibrinogen / Q000032:analysis; D007136:Immunoglobulins / Q000032:analysis; D051379:Mice; D014168:Transferrin / Q000032:analysis; D014774:Virulence
chemical_list: D001798:Blood Proteins; D007136:Immunoglobulins; D014168:Transferrin; D005340:Fibrinogen