title: Maximum likelihood estimation of linkage between a marker gene and a quantitative trait locus. II. Application to backcross and doubled haploid populations.
abstract: The algorithm for estimating both the recombination fraction between a marker gene and a locus affecting a quantitative trait, and also the means and variances of the QTL genotypes, is extended to backcross and doubled haploid populations. The simulation experiments show that estimates of these parameters can be obtained with acceptable accuracy and results are compared with those obtained using F2 populations studied previously (Luo & Kearsey, 1989).
authors.affiliation: School of Biological Sciences, University of Birmingham, UK.
authors.forename: Z W
authors.initials: ZW
authors.lastname: Luo
authors.forename: M J
authors.initials: MJ
authors.lastname: Kearsey
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D003433:Crosses, Genetic; D008040:Genetic Linkage; D005819:Genetic Markers / Q000235:genetics*; D006238:Haploidy; D008433:Mathematics; D008957:Models, Genetic
chemical_list: D005819:Genetic Markers