Hyperoxia increases salt intake in spontaneously hypertensive rats (SHR).
The effect of normobaric hyperoxia on voluntary salt intake was investigated in 20 sham-operated and 11 carotid body-denervated SHR. While in sham-operated SHR the saline intake was enhanced during the whole hyperoxic period, the carotid body-denervated rats showed an increase in salt appetite only on the second and third day of hyperoxia. Water intake was not significantly different in sham-operated and carotid body-denervated SHR. These findings, together with our previous results, suggest that chemoreceptor activity determines salt appetite but not water intake in SHR.
Behm
R
R
Department of Physiology, Wilhelm-Pieck-University, Rostock, Germany.
Rückborn
K
K
Franz
U
U
D000818:Animals; D001066:Appetite / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D002344:Carotid Body / Q000502:physiology*; D002628:Chemoreceptor Cells / Q000502:physiology; D004326:Drinking / Q000502:physiology; D010100:Oxygen / Q000502:physiology*; D051381:Rats; D011918:Rats, Inbred SHR; D012965:Sodium Chloride / Q000008:administration & dosage*
D012965:Sodium Chloride; D010100:Oxygen