title: Effect of early season ivermectin and pyrantel treatments on strongylid infections in young Shetland ponies in The Netherlands.
abstract: Two groups of three ponies were used to study the effect of three ivermectin or pyrantel treatments given at intervals of 5 weeks at the beginning of the grazing season. Although each pyrantel treatment resulted in a greater than 95% reduction in faecal egg counts during the first 3 weeks, high pasture larval counts were seen from the beginning of August onwards and substantial cyathostomine burdens were found at necropsy in December. The ivermectin treatments resulted in an even more pronounced reduction in faecal egg output, and the pasture larval counts and cyathostomine burdens at necropsy were considerably lower than in the pyrantel group. The proportion of inhibited early L3 of the cyathostomines was lower in the ivermectin than in the pyrantel group. Faecal egg output of the large strongyles was completely suppressed in the ivermectin group. Nevertheless, Strongylus vulgaris larvae were found in the arteries of all three ponies, possibly as a result of overwintering of infective larvae on pasture. In the pyrantel group, the egg output of Strongylus edentatus and, to a much lesser extent, Strongylus vulgaris, was not completely suppressed.
authors.affiliation: Department of Infectious Diseases and Immunology, University of Utrecht, The Netherlands.
authors.forename: M
authors.initials: M
authors.lastname: Eysker
authors.forename: J H
authors.initials: JH
authors.lastname: Boersema
authors.forename: F N
authors.initials: FN
authors.lastname: Kooyman
mesh_terms: D000818:Animals; D005243:Feces / Q000469:parasitology; D005260:Female; D006736:Horses; D007559:Ivermectin / Q000627:therapeutic use*; D009426:Netherlands; D010270:Parasite Egg Count / Q000662:veterinary; D011715:Pyrantel / Q000627:therapeutic use*; D011897:Random Allocation; D012621:Seasons; D013319:Strongyle Infections, Equine / Q000517:prevention & control*
chemical_list: D011715:Pyrantel; D007559:Ivermectin