title: Changes of blood pressure and lipid pattern during a physical training course in hypertensive subjects.
abstract: Among 77 hypertensive subjects with a previous predominantly sedentary way of life we followed the changes of several cardiovascular and biochemical parameters during a 5-week physical training course. A highly significant drop in both systolic and diastolic blood pressure (BP) was observed in 58 subjects (75%, p less than 0.001). There was a strong negative correlation between initial uricaemia and the diastolic BP decrease (r = -0.382; p less than 0.001). The decrease of systolic as well as diastolic BP correlated positively with the increase of maximum oxygen uptake per kilogram (VO2max/kg) during the intervention (for systolic BP: r = 0.282, p less than 0.05; for diastolic BP: r = 0.286, p less than 0.05). Serum total cholesterol (TC), triglycerides (TG), HDL-cholesterol (HDL-C), uricaemia levels and body mass index (BMI) decreased (p less than 0.01 for uricaemia; p less than 0.001 for the rest), whereas the HDL-C/TC ratio increased significantly (p less than 0.001). These positive changes disappeared already 3-7 months after the intervention except for BMI, TG and uricemia, where the lower levels persisted. Thus, the 5-week intensive physical training had a favourable but short-time effect on BP and lipid pattern in the majority of hypertensives.
authors.affiliation: 2nd Department of Internal Medicine, Medical Faculty, Charles University, Plzen, Czechoslovakia.
authors.forename: J
authors.initials: J
authors.lastname: Filipovský
authors.forename: J
authors.initials: J
authors.lastname: Simon
authors.forename: J
authors.initials: J
authors.lastname: Chrástek
authors.forename: H
authors.initials: H
authors.lastname: Rosolová
authors.forename: P
authors.initials: P
authors.lastname: Haman
authors.forename: V
authors.initials: V
authors.lastname: Petríková
mesh_terms: D001794:Blood Pressure / Q000502:physiology*; D015992:Body Mass Index; D015444:Exercise / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000503:physiopathology* / Q000534:rehabilitation; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010806:Physical Education and Training; D010809:Physical Fitness / Q000502:physiology; D013997:Time Factors; D014527:Uric Acid / Q000097:blood
chemical_list: D008055:Lipids; D014527:Uric Acid