title: [Studies on HLA typing in a family line with spontaneous pneumothorax].
abstract: Our patient with spontaneous pneumothorax is the oldest brother of 3 siblings. Pneumothorax had occurred in his younger sister and in 3 of his mother's 4 siblings also. Namely, pneumothorax had occurred in 5 (including our patient) of 7 persons, family line on mother's side, and thoracotomy had been performed in 3 of them. Two cases in which operative findings were obtained were introduced. Next, HLA and alpha 1-antitrypsin (alpha 1-AT) were determined in this family line. As the result, the alpha 1-AT all remained in the normal range and HLA typing was not in a special relation to the occurrence of pneumothorax in this family line.
authors.affiliation: Department of Surgery, Osaka Municipal Citizen's Hospital.
authors.forename: H
authors.initials: H
authors.lastname: Nakamura
authors.forename: K
authors.initials: K
authors.lastname: Tsukioka
authors.forename: H
authors.initials: H
authors.lastname: Tanaka
authors.forename: T
authors.initials: T
authors.lastname: Okimoto
authors.forename: K
authors.initials: K
authors.lastname: Mizukami
authors.forename: H
authors.initials: H
authors.lastname: Muramatsu
authors.forename: S
authors.initials: S
authors.lastname: Fukuda
authors.forename: K
authors.initials: K
authors.lastname: Unno
authors.forename: S
authors.initials: S
authors.lastname: Hirata
mesh_terms: D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D011030:Pneumothorax / Q000235:genetics* / Q000276:immunology
chemical_list: D006680:HLA Antigens