title: Cytogenetic analysis of a congenital fibrosarcoma.
abstract: Congenital (infantile) fibrosarcoma is a rare soft tissue sarcoma occurring in children aged less than 5 years. We performed cytogenetic analysis on such a tumor, which had an abnormal karyotype: 48,XY, +11, +20. Three other reports of karyotypes in congenital fibrosarcoma describe similar cytogenetic changes, and a specific pattern of trisomies that may prove diagnostic for this tumor is beginning to emerge.
authors.affiliation: Division of Human Genetics, University of Newcastle upon Tyne, England.
authors.forename: L R
authors.initials: LR
authors.lastname: Adam
authors.forename: E V
authors.initials: EV
authors.lastname: Davison
authors.forename: A J
authors.initials: AJ
authors.lastname: Malcolm
authors.forename: A D
authors.initials: AD
authors.lastname: Pearson
authors.forename: A W
authors.initials: AW
authors.lastname: Craft
mesh_terms: D005354:Fibrosarcoma / Q000151:congenital* / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D007866:Leg; D008297:Male; D012983:Soft Tissue Neoplasms / Q000151:congenital* / Q000235:genetics*