title: Frog brain expresses a 60 KDa Ca2+ binding protein similar to mammalian calreticulin.
abstract: The present report was undertaken in an effort to characterize the nature of Ca2+ binding protein(s) in the central nervous system of less evolved vertebrates. In particular we investigated whether the brain microsomal fraction of Rana esculenta expresses calsequestrin, calreticulin and/or other related Ca2+ binding protein(s). We found that a 60 KDa protein having an NH2-terminal amino acid sequence similar to mammalian calreticulin is the major microsomal Ca2(+)-binding protein.
authors.affiliation: Istituto di Patologia Generale, Università di Ferrara, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Trevesø
authors.forename: F
authors.initials: F
authors.lastname: Zorzato
authors.forename: P
authors.initials: P
authors.lastname: Chiozzi
authors.forename: P
authors.initials: P
authors.lastname: Melandri
authors.forename: P
authors.initials: P
authors.lastname: Volpe
authors.forename: T
authors.initials: T
authors.lastname: Pozzan
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D015153:Blotting, Western; D001921:Brain / Q000502:physiology; D002135:Calcium-Binding Proteins / Q000737:chemistry / Q000378:metabolism*; D037282:Calreticulin; D002155:Calsequestrin / Q000737:chemistry / Q000378:metabolism; D004591:Electrophoresis, Polyacrylamide Gel; D008969:Molecular Sequence Data; D011893:Rana esculenta / Q000502:physiology*; D013045:Species Specificity
chemical_list: D002135:Calcium-Binding Proteins; D037282:Calreticulin; D002155:Calsequestrin