[Arthrogryposis and maternal myasthenia gravis. Risk of recurrence].
A 26-year old myasthenic woman whose disease had been in remission for more than 4 years gave birth, at the end of 2 induced pregnancies, to 2 stillborn infants with arthrogryposis. The presence of inherited antibodies directed against acetylcholine receptors most probably does not explain the diffuse retractions. This case illustrates the risk of recurrent foetal arthrogryposis after a first abnormal pregnancy in women with myasthenia gravis.
Tranchant
C
C
Clinique Neurologique, Centre Hospitalo-Universitaire de Strasbourg.
Ehret
C
C
Labouret
P
P
Gasser
B
B
Warter
J M
JM
D000328:Adult; D000906:Antibodies / Q000502:physiology; D001176:Arthrogryposis / Q000209:etiology*; D005260:Female; D005315:Fetal Diseases / Q000209:etiology*; D006801:Humans; D009157:Myasthenia Gravis / Q000276:immunology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology; D011950:Receptors, Cholinergic / Q000276:immunology; D012008:Recurrence; D012307:Risk Factors
D000906:Antibodies; D011950:Receptors, Cholinergic