title: Molecular cloning and chromosomal mapping of a human galactoside-binding protein.
abstract: A human galactoside-binding protein with an Mr of 31,000 was cloned from the human HT-1080 fibrosarcoma complementary DNA library. A partial complementary DNA clone containing the complete coding region was characterized and the deduced sequence encodes a polypeptide of 242 amino acids with the characteristics of a carbohydrate-binding protein. The gene coding for the human galactoside-binding protein was mapped to the chromosomal band 1p13. The deduced amino acid sequence of the human galactoside-binding protein revealed 95 residues at the amino terminus, homologous to the predicted amino acid sequence of the second exon of the human L-myc gene.
authors.affiliation: Cancer Metastasis Program, Michigan Cancer Foundation, Detroit 48201.
authors.forename: A
authors.initials: A
authors.lastname: Raz
authors.forename: P
authors.initials: P
authors.lastname: Carmi
authors.forename: T
authors.initials: T
authors.lastname: Raz
authors.forename: V
authors.initials: V
authors.lastname: Hogan
authors.forename: A
authors.initials: A
authors.lastname: Mohamed
authors.forename: S R
authors.initials: SR
authors.lastname: Wolman
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D002871:Chromosome Banding; D002878:Chromosomes, Human, Pair 1; D037161:Galectins; D006388:Hemagglutinins / Q000737:chemistry* / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D009693:Nucleic Acid Hybridization; D012333:RNA, Messenger / Q000737:chemistry*; D016415:Sequence Alignment; D012689:Sequence Homology, Nucleic Acid; D013045:Species Specificity
chemical_list: D037161:Galectins; D006388:Hemagglutinins; D012333:RNA, Messenger