title: Cancer prevention clinical trials.
abstract: If external factors other than tobacco (e.g., diet, sunlight) are responsible in a major way for some cancers, then appropriate manipulation and alteration of such factors should decrease the rate of these cancers. Clinical trials in cancer prevention are an attempt to test this approach. Prevention trials are based on knowledge gained from the laboratory and from epidemiology, and they are the only way to conclusively demonstrate the effectiveness of a given prevention intervention in humans. This article discusses the development of prevention trials and specific current and future trials.
authors.affiliation: American Cancer Society, Atlanta, Georgia.
authors.forename: D W
authors.initials: DW
authors.lastname: Nixon
mesh_terms: D002986:Clinical Trials as Topic; D006801:Humans; D009369:Neoplasms / Q000517:prevention & control*