[Genomic pharmacology].
The aim of genomic pharmacology is to discover substances able to influence the expression of specific genes. These substances could be used in many pathologies in which the expression of specific genes is abnormal and in the control of viral infection. The potential targets of genomic pharmacology may be classified in two groups: first, the proteins regulating genetic expression, and, second, the nucleic acids which carry the genetic information. The preliminary results obtained with antidirectional nucleic acids are presented and discussed.
Bracco
L
L
Institut de biotechnologie, centre de recherche de Vitry, Vitry-sur-Seine.
Le Pecq
J B
JB
D004268:DNA-Binding Proteins / Q000494:pharmacology; D015870:Gene Expression / Q000187:drug effects*; D015698:Genomic Library; D006801:Humans; D016350:Leucine Zippers / Q000502:physiology; D016376:Oligonucleotides, Antisense / Q000494:pharmacology; D010601:Pharmacology, Clinical; D016337:RNA, Catalytic / Q000494:pharmacology; D016335:Zinc Fingers / Q000502:physiology
D004268:DNA-Binding Proteins; D016376:Oligonucleotides, Antisense; D016337:RNA, Catalytic