A new case of IgE myeloma.
A new case of IgE myeloma is described. A 77-year-old woman presented with bone pain and fatigue. Serum protein analysis revealed a paraprotein of the IgE kappa type; bone marrow aspirate and immunofluorescence confirmed the diagnosis; ultrastructural examination showed immature plasma cells. Treatment with prednisone, melphalan, cyclophosphamide and interferon alfa did not produce any improvement and the patient died 5 months after diagnosis. The patient's clinical and laboratory data are compared with those of IgE myeloma cases reported in the literature.
Invernizzi
F
F
Institute of Internal Medicine, Infectious Diseases, Immunopathology, University of Milan, Italy.
Monti
G
G
Caviglia
A G
AG
Meroni
P
P
Zanussi
C
C
D000368:Aged; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D009101:Multiple Myeloma / Q000276:immunology*
D007073:Immunoglobulin E