title: Dendritic activity on neostriatal neurons as inferred from somatic intracellular recordings.
abstract: Orthodromic responses after local field stimulation were studied in a neostriatal slice preparation. Single suprathreshold stimuli evoked slow plateau-like orthodromic responses with repetitive firing and duration proportional to the stimulus intensity. Its persistence and apparent threshold upon hyperpolarization, as well as the actions of tetraethylammonium, QX-314 and Sr2+, suggest that this orthodromic response and associated phenomena such as fast prepotentials or Ca-dependent action potentials, may be generated on dendrites.
authors.affiliation: Departamento de Fisiología, Biofísica y Neurociencias, CINVESTAV-IPN, México, D.F.
authors.forename: J
authors.initials: J
authors.lastname: Bargas
authors.forename: E
authors.initials: E
authors.lastname: Galarraga
authors.forename: J
authors.initials: J
authors.lastname: Aceves
mesh_terms: D000200:Action Potentials / Q000187:drug effects; D000779:Anesthetics, Local / Q000494:pharmacology; D000818:Animals; D003342:Corpus Striatum / Q000502:physiology*; D003712:Dendrites / Q000187:drug effects / Q000502:physiology*; D004558:Electric Stimulation; D005071:Evoked Potentials / Q000187:drug effects; D066298:In Vitro Techniques; D008012:Lidocaine / Q000031:analogs & derivatives / Q000494:pharmacology; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D013324:Strontium / Q000494:pharmacology; D019789:Tetraethylammonium; D013757:Tetraethylammonium Compounds / Q000494:pharmacology
chemical_list: D000779:Anesthetics, Local; D013757:Tetraethylammonium Compounds; C012647:QX-314; D019789:Tetraethylammonium; D008012:Lidocaine; D013324:Strontium