title: Choriocarcinoma of the testis metastatic to the skin.
abstract: A case of choriocarcinoma of the testis metastatic to the skin is reported. In this case report the primary tumor was first diagnosed by the histopathologic findings in the cutaneous biopsy of a single nodule that appeared on the chest, with both syncytiotrophoblastic and cytotrophoblastic cells in the metastatic solid tumor islands. Using peroxidase-antiperoxidase techniques, beta-human chorionic gonadotropin (beta-HCG) was positive within the cytoplasm of syncytiotrophoblastic cells. The patient was treated with orchiectomy, chemotherapy, and radiotherapy. With these measures there was a decrease of chorionic gonadotropin serum levels to normal limits and 2 years after this treatment there is no evidence of recurrence.
authors.affiliation: Departamento de Dermatología, Hospital Universitario San Carlos, Facultad de Medicina, Universidad Complutense, Madrid, Spain.
authors.forename: L
authors.initials: L
authors.lastname: Requena
authors.forename: M
authors.initials: M
authors.lastname: Sánchez
authors.forename: A
authors.initials: A
authors.lastname: Aguilar
authors.forename: E
authors.initials: E
authors.lastname: Sánchez Yus
mesh_terms: D000328:Adult; D002822:Choriocarcinoma / Q000556:secondary*; D006801:Humans; D008297:Male; D012878:Skin Neoplasms / Q000556:secondary*; D013736:Testicular Neoplasms / Q000473:pathology*