title: [Hepatitis B and D recurrence after liver transplantation].
abstract: In Italy, many patients with B-virus (HBV) and Delta-virus (HDV) end-stage liver disease, are potential candidates to liver transplantation. Several authors have reported 70 to 100% hepatitis recurrence rates. From june 1983 to may 1989, 72 transplants on 60 patients were performed at Liver Transplantation Department of the Maggiore-Policlinico Hospital of Milan. The results in 26 HBsAg positive patients (19 with HDV infection), that underwent liver transplantation, are reported. A detailed report of 17 of these patients with a follow-up longer 7 months, and the clinical course of 4 patients with HBV reinfection, 3 of which had hepatitis recurrence, is also presented. The occurrence of HDV-RNA in the serum of 5 patients, that were negative for HBsAg and also other HBV-HDV replication markers after transplantation is discussed, together with the observation that in these patients no hepatitis recurrences or alteration of the clinical course were evident.
authors.affiliation: Ospedale Maggiore Policlinico, Milano.
authors.forename: M
authors.initials: M
authors.lastname: Grendele
authors.forename: M
authors.initials: M
authors.lastname: Colledan
authors.forename: M
authors.initials: M
authors.lastname: Doglia
authors.forename: L R
authors.initials: LR
authors.lastname: Fassati
authors.forename: G
authors.initials: G
authors.lastname: Ferla
authors.forename: B
authors.initials: B
authors.lastname: Gridelli
authors.forename: U
authors.initials: U
authors.lastname: Maggi
authors.forename: P
authors.initials: P
authors.lastname: Reggiani
authors.forename: G
authors.initials: G
authors.lastname: Rossi
authors.forename: L
authors.initials: L
authors.lastname: Caccamo
mesh_terms: D015415:Biomarkers / Q000097:blood; D005500:Follow-Up Studies; D006509:Hepatitis B / Q000453:epidemiology* / Q000517:prevention & control; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006513:Hepatitis B e Antigens / Q000097:blood; D003699:Hepatitis D / Q000453:epidemiology* / Q000517:prevention & control; D006801:Humans; D007165:Immunosuppression Therapy; D007558:Italy / Q000453:epidemiology; D016031:Liver Transplantation; D011183:Postoperative Complications / Q000453:epidemiology* / Q000517:prevention & control; D012008:Recurrence; D012086:Reoperation; D014761:Viral Hepatitis Vaccines / Q000276:immunology
chemical_list: D015415:Biomarkers; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens; D014761:Viral Hepatitis Vaccines