title: Recent advances in the treatment of breast cancer.
abstract: Multidisciplinary efforts have defined a number of prognostic factors and newer strategies to improve the outcome of patients with breast cancer. Conservative surgery has led to improved functional and cosmetic results. The development of a number of effective adjuvant regimens has led to improved survival. In patients with stage I disease, several biological characteristics of tumor have been identified that are associated with increased risk of relapse. A multimodality approach to patients with locally advanced disease and inflammatory cancer has resulted in improved survival. A number of hormonal and cytotoxic drug contaminations can palliate metastatic disease, with a small fraction of patients remaining in extended remission. Dose-intensive programs may lead to further improvements in survival of selected patients with this disease.
authors.affiliation: Department of Medicine (Medical Breast), University of Texas, M.D. Anderson Cancer Center, Houston 77030.
authors.forename: L D
authors.initials: LD
authors.lastname: Ziegler
authors.forename: A U
authors.initials: AU
authors.lastname: Buzdar
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D006801:Humans; D009362:Neoplasm Metastasis