[Acute leukemia successfully treated with natural interferon-alpha].
Natural interferon-alpha (IFN-alpha) alone was administered to a 42-year-old man with acute leukemia, whose bone marrow revealed hypocellularity (NCC = 6 X 10(4)/microliters) and a 50% increase in blasts. Initial chemotherapy regimens, including BHAC-DMP or low dose Ara-C were ineffective. One month after starting nIFN-alpha therapy, the blasts in his bone marrow decreased below 3% and peripheral blood cell counts became normal. He has been in remission for at least 7 months.
Moriya
K
K
First Department of Internal Medicine, Faculty of Medicine, University of Tokyo.
Miura
N
N
Sunaga
S
S
Horie
R
R
Aoki
K
K
Yatomi
Y
Y
Yoneyama
A
A
Higashihara
M
M
Tanabe
A
A
Nakahara
K
K
D000208:Acute Disease; D000328:Adult; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use*; D007938:Leukemia / Q000628:therapy*; D008297:Male
D007370:Interferon Type I