[Distribution and antibiotic resistance of aerobic bacteria isolated from infected wounds caused by burns].
Distribution according to species and genus and resistance to antibacterial agents was studied with 420 bacterial isolates cultured from the wound excretion of 282 burned-infected patients. Of the isolates 68.2% was Gram-positive and 31.8% Gram-negative. This latter high rate may be due to fecal infection as 21% of the burned patients was between the age of 0-4 years. Of the total isolates 38.3% was Staphylococcus aureus, 16.7% coagulase-negative staphylococcus, 10.7% Pseudomonas strain, 6.9% Escherichia coli and 4.8% Klebsiella. Vancomycin resistant Staphylococcus strain was not found. On the other hand 30-35% of the strains was cross-resistant to methicillin- oxacillin-cefuroxim-clindamycin though these agents are the most potent following the vancomycine. Ceftazidime is the most effective agent for Pseudomonas strains being followed by amikacin, carbenicillin, tobramycin and ceftriaxon. Other Gram-negative bacteria showed strongest sensitivity to ceftazidime and ceftriaxone and these are followed by amikacin.
Szabó
J
J
Debreceni Orvostudományi Egyetem Mikrobiológiai Intézet.
Belicza
E
E
Rédal
I
I
Rozgonyi
F
F
D000328:Adult; D000367:Age Factors; D001420:Bacteria, Aerobic / Q000187:drug effects / Q000302:isolation & purification*; D001424:Bacterial Infections / Q000382:microbiology*; D002056:Burns / Q000382:microbiology*; D002981:Clindamycin / Q000494:pharmacology / Q000627:therapeutic use; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D014946:Wound Infection / Q000209:etiology / Q000382:microbiology* / Q000517:prevention & control
D002981:Clindamycin