title: Serum TAG 72 levels in different human carcinomas.
abstract: Since December 1988, we have measured the TAG 72 serum levels in 326 patients with different carcinomas, especially breast, gastrointestinal and ovarian, using a RIA kit. With a cut-off value of 5 U/mL, a specificity of 100% in the controls and an overall sensitivity of 22% in the neoplastic patients was obtained, with the highest positivities in ovarian (63%) and gastric (58%) carcinomas. Therefore, TAG 72 can be associated with other tumor markers for these latter neoplasms.
authors.affiliation: Clinical Chemistry Laboratory, RIA Unit, Oncology Institute of Bari, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Correale
authors.forename: I
authors.initials: I
authors.lastname: Abbate
authors.forename: G
authors.initials: G
authors.lastname: Gargano
authors.forename: M
authors.initials: M
authors.lastname: Garrubba
authors.forename: A
authors.initials: A
authors.lastname: Muncipinto
authors.forename: L
authors.initials: L
authors.lastname: Addabbo
authors.forename: D
authors.initials: D
authors.lastname: Colangelo
mesh_terms: D000951:Antigens, Neoplasm / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood*; D001943:Breast Neoplasms / Q000097:blood; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000097:blood; D006023:Glycoproteins / Q000097:blood*; D006801:Humans; D009369:Neoplasms / Q000097:blood*; D010051:Ovarian Neoplasms / Q000097:blood
chemical_list: D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D006023:Glycoproteins; C047052:tumor-associated antigen 72