The influence of gestational dietary calcium on serum 1, 25-dihydroxycholecalciferol in sows and their pigs.
Fifteen multiparous sows (three groups of five) were studied during one gestation-lactation cycle to measure the influence of dietary Ca (.5, .8[control], and 1.1%) on 1,25-dihydroxycholecalciferol (1, 25-(OH)2D3) in serum and colostrum of the sows and serum of their pigs. Concentrations of 1,25-(OH)2D3 and Ca, Mg, P, Cu, and Zn were determined on d 15 and 45 of gestation, at parturition, and at 3 wk postpartum in sow serum and at birth and d 10 and 21 in pig serum. Colostrum was assayed for 1,25-(OH)2D3. Serum 1,25-(OH)2D3 in sows was affected inversely (P less than .05) by dietary Ca within d 15 of gestation and was correlated (r = -.88) with serum Ca during gestation and lactation. Serum Ca was correlated (r = .52) with dietary Ca at d 15 and 45 of gestation and at farrowing. Sow serum Mg was inversely related (r = -.49) to serum Ca during gestation and early lactation. Serum 1,25-(OH)2D3 of the pigs at birth ranged from 38.7 to 44.2 pg/ml was decreased (P less than .05) by 1.1% maternal Ca intake. Sow colostrum 1,25-(OH)2D3 was related (P less than .05) inversely (r = -.40) to sow dietary Ca and directly (r = .90) to sow serum 1,25-(OH)2D3. Serum 1,25-(OH)2D3 of 10- and 21-d-old pigs was inversely related (P less than .05) to their dams' dietary Ca. These results indicate that 1,25-(OH)2D3 production in sows is quickly affected by modest changes in dietary Ca.(ABSTRACT TRUNCATED AT 250 WORDS)
Wuryastuti
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Dept. of Large Anim. Clin. Sci., Michigan State University, East Lansing 48824-1314.
Stowe
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Miller
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D000818:Animals; D002117:Calcitriol / Q000032:analysis / Q000097:blood*; D002118:Calcium / Q000097:blood; D002136:Calcium, Dietary / Q000494:pharmacology*; D003126:Colostrum / Q000737:chemistry; D003300:Copper / Q000097:blood; D005260:Female; D008274:Magnesium / Q000097:blood; D010758:Phosphorus / Q000097:blood; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000097:blood*; D011897:Random Allocation; D013552:Swine / Q000097:blood*; D015032:Zinc / Q000097:blood
D002136:Calcium, Dietary; D010758:Phosphorus; D003300:Copper; D002117:Calcitriol; D008274:Magnesium; D015032:Zinc; D002118:Calcium