[HTLV-I infection: ungual T-cell lymphoma as a primary manifestation].
A 34-year-old woman presented with leathery thickening and haemorrhagic lesions of several finger- and toe-nails as first symptoms of an HTLV-I infection. Histology resembled that found in mycosis fungoides. Later signs of T cell deficiency (e.g. Pneumocystis carinii pneumonia) developed. An erythemato-papular exanthema representing T cell lymphoma with Pautrier's abscesses preceded her death 1 year later. The detection of HTLV-I antibodies helped to establish the diagnosis following initial confusion owing to elevation of the T-helper cells and the CD4/CD8 ratio.
Wolter
M
M
Abteilung, Zentrum der Dermatologie und Venerologie, Johann Wolfgang Goethe-Universität Frankfurt am Main.
Schleussner-Samuel
P
P
Marsch
W C
WC
D000328:Adult; D005260:Female; D015490:HTLV-I Infections / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000150:complications* / Q000473:pathology; D009260:Nail Diseases / Q000150:complications*; D012878:Skin Neoplasms / Q000150:complications* / Q000473:pathology