[Myocarditis in childhood].
Infectious heart diseases in childhood are--with less than 1% of hospital admissions--rare, but serious diseases. Among several causes of myocarditis in our region virus myocarditis plays the most important role. Besides of the acute course an autoimmune mediated chronic myocarditis and the transition to dilated cardiomyopathy are observed. The patho-histological assessment depends also on subjective influences. Clinical diagnosis is based on cardiac symptoms (Adams-Stokes, congestive heart failure, LV-dilatation), ECG-changes with increased enzyme levels and positive virus-serology or endomyocardial biopsy. Immunoserology and -histology as well as in-situ-hybridization can support diagnosis, echocardiography and eventually heart catheterization exclude other causes. In respect to therapy, ACE-inhibitors are a substantial improvement of conventional therapy of heart failure, while immunosuppressive therapy of chronic myocarditis has to assessed.
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Abteilung für pädiatrische Kardiologie, Universitätsklinikum, GHS, Essen.
D002648:Child; D003937:Diagnosis, Differential; D006801:Humans; D009205:Myocarditis / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D009206:Myocardium / Q000473:pathology