title: The cosmetic ingredient review self-regulatory safety program.
abstract: The CIR's 13-year history of cosmetic-ingredient safety review appears to have successfully accomplished its goal of reviewing in a scientific manner the safety of cosmetic chemical ingredients. The method of prioritization has allowed for the identification of the most frequently used and the most biologically active chemicals. To date, 310 cosmetic ingredients have been reviewed, and 33 ingredients are under current review. Although CIR does not have a safety-evaluation report available for every cosmetic ingredient in use, it has proved that CIR is a system of documentation, review, and analysis that can be used to address any safety problem that may exist with any cosmetic ingredient.
authors.affiliation: Department of Dermatology, Cleveland Clinic Foundation, Ohio.
authors.forename: W F
authors.initials: WF
authors.lastname: Bergfeld
authors.forename: R L
authors.initials: RL
authors.lastname: Elder
authors.forename: A L
authors.initials: AL
authors.lastname: Schroeter
mesh_terms: D003358:Cosmetics / Q000737:chemistry* / Q000592:standards; D006801:Humans; D007221:Industry / Q000331:legislation & jurisprudence*; D004364:Pharmaceutical Preparations / Q000737:chemistry; D012042:Registries; D012449:Safety; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D003358:Cosmetics; D004364:Pharmaceutical Preparations