title: Localization of monocyte chemotactic protein-1 gene (SCYA2) to human chromosome 17q11.2-q21.1.
abstract: Monocyte chemotactic protein-1 (MCP-1) is a member of the small inducible gene (SIG) family. It has been shown to play a role in the recruitment of monocytes to sites of injury and infection. By analysis of a panel of somatic cell hybrids, we have localized the MCP-1 gene, designated SCYA2, to human chromosome 17. In situ hybridization confirmed this assignment and further localized the gene to 17q11.2-q21.1.
authors.affiliation: Division of Cardiology, University of California, Los Angeles 90024.
authors.forename: M
authors.initials: M
authors.lastname: Mehrabian
authors.forename: R S
authors.initials: RS
authors.lastname: Sparkes
authors.forename: T
authors.initials: T
authors.lastname: Mohandas
authors.forename: A M
authors.initials: AM
authors.lastname: Fogelman
authors.forename: A J
authors.initials: AJ
authors.lastname: Lusis
mesh_terms: D000818:Animals; D001483:Base Sequence; D018932:Chemokine CCL2; D002630:Chemotactic Factors / Q000235:genetics*; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002886:Chromosomes, Human, Pair 17; D005796:Genes; D006801:Humans; D006822:Hybrid Cells; D051379:Mice; D008969:Molecular Sequence Data; D009000:Monocytes
chemical_list: D018932:Chemokine CCL2; D002630:Chemotactic Factors