Caffeine, blood pressure, and serum lipids.
To study the effects of caffeine on serum lipids and blood pressure, we conducted a double-blind, randomized trial with two parallel groups in 69 young, healthy subjects. After a 3-wk run-in period, subjects were randomly assigned to one of two groups receiving either 4-6 140-mL cups filtered decaffeinated coffee per day and an equal number of pills containing 75 mg caffeine or 4-6 140-mL cups filtered decaffeinated coffee per day and an equal number of placebo pills, for 9 wk. In both groups caffeine intake from other sources was not allowed. The main finding of this study is that abstinence from caffeine for a period of 9 wk has no effect on either serum lipids or blood pressure.
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Department of Epidemiology and Biostatistics, Erasmus University Rotterdam, The Netherlands.
Grobbee
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D000328:Adult; D001794:Blood Pressure / Q000187:drug effects*; D002110:Caffeine / Q000008:administration & dosage / Q000378:metabolism / Q000494:pharmacology*; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003069:Coffee; D004041:Dietary Fats / Q000008:administration & dosage; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D012463:Saliva / Q000378:metabolism
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D003069:Coffee; D004041:Dietary Fats; D008055:Lipids; D002110:Caffeine; D002784:Cholesterol