[Studies on HLA typing in a family line with spontaneous pneumothorax].
Our patient with spontaneous pneumothorax is the oldest brother of 3 siblings. Pneumothorax had occurred in his younger sister and in 3 of his mother's 4 siblings also. Namely, pneumothorax had occurred in 5 (including our patient) of 7 persons, family line on mother's side, and thoracotomy had been performed in 3 of them. Two cases in which operative findings were obtained were introduced. Next, HLA and alpha 1-antitrypsin (alpha 1-AT) were determined in this family line. As the result, the alpha 1-AT all remained in the normal range and HLA typing was not in a special relation to the occurrence of pneumothorax in this family line.
Nakamura
H
H
Department of Surgery, Osaka Municipal Citizen's Hospital.
Tsukioka
K
K
Tanaka
H
H
Okimoto
T
T
Mizukami
K
K
Muramatsu
H
H
Fukuda
S
S
Unno
K
K
Hirata
S
S
D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D011030:Pneumothorax / Q000235:genetics* / Q000276:immunology
D006680:HLA Antigens