title: [Effects of fibrinolysis on late potentials in myocardial infarction].
abstract: Late potentials are an index of gravity following myocardial infarction, but there has been little investigation of the effects of fibrinolysis on their incidence. Eighty-two consecutive patients (68 men, 14 women, group men age = 55 +/- 8 years) admitted presenting with a primary infarction and who had received fibrinolytic treatment within the first four hours. Each patient was screened for late potentials, and underwent a coronary artery angiograph and determination of the left ventricular ejaculation fraction (LCEF) following the infarction. The incidence of late potentials was 38% in the patients with an occluded coronary artery (9/24) vs 12% in patients with a permeable artery (7/58) (p less than 0.02). The change in LVEF was greater if reperfusion was not achieved (47 +/- 13% vs 54 +/- 12%, p less than 0.05). This study suggests that following fibrinolysis, the incidence of late potentials is correlated with both an absence of coronary reperfusion and deterioration of left ventricular function.
authors.affiliation: Service de Cardiologie, Hôpital Central, CHRU de Nancy.
authors.forename: C
authors.initials: C
authors.lastname: de Chillou
authors.forename: N
authors.initials: N
authors.lastname: Sadoul
authors.forename: F
authors.initials: F
authors.lastname: Brunotte
authors.forename: M
authors.initials: M
authors.lastname: Pichene
authors.forename: E
authors.initials: E
authors.lastname: Aliot
mesh_terms: D000328:Adult; D000368:Aged; D005071:Evoked Potentials / Q000187:drug effects*; D005260:Female; D005343:Fibrinolytic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy / Q000503:physiopathology*
chemical_list: D005343:Fibrinolytic Agents