Diffuse-plane normolipaemic xanthoma with aortic-valve xanthoma.
A patient with diffuse-plane normolipaemic xanthomatosis had mucous-membrane, conjunctival, and aortic-valve xanthomatosis. The presence of a monoclonal protein and hypocomplementaemia suggests that the xanthomatous lesions were probably not metabolic in origin but developed as secondary events in a histiocytosis of involved tissues. No heart-valve xanthomatization in like circumstances has previously been reported.
Winkelmann
R K
RK
Department of Dermatology, Mayo Clinic, Rochester, Minnesota.
McEvoy
M T
MT
D001021:Aortic Valve / Q000473:pathology*; D003228:Conjunctiva / Q000473:pathology; D003229:Conjunctival Diseases / Q000473:pathology; D006349:Heart Valve Diseases / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009092:Mucous Membrane / Q000473:pathology; D014973:Xanthomatosis / Q000473:pathology*