title: Carcinoma of the vulva with sarcomatoid features: a case report with immunohistochemical study.
abstract: A tumor of the vulva with sarcomatoid features was studied by immunocytochemistry to characterize the phenotype of the spindle-shaped and giant cells. Sarcomatoid-looking cells were positive for intermediate filament keratin polypeptides of stratified epithelium. These results favor histogenesis of the sarcomatoid-looking cells from a metaplastic alteration of the malignant squamous component.
authors.affiliation: Cattedra di Anatomia e Istologia Patologica, II Università di Roma, Tor Vergata, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Santeusanio
authors.forename: S
authors.initials: S
authors.lastname: Schiaroli
authors.forename: L
authors.initials: L
authors.lastname: Anemona
authors.forename: F
authors.initials: F
authors.lastname: Sesti
authors.forename: E
authors.initials: E
authors.lastname: Valli
authors.forename: E
authors.initials: E
authors.lastname: Piccione
authors.forename: L G
authors.initials: LG
authors.lastname: Spagnoli
mesh_terms: D000368:Aged; D002277:Carcinoma / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D012509:Sarcoma / Q000473:pathology*; D014846:Vulvar Neoplasms / Q000378:metabolism / Q000473:pathology*