title: Morphological characteristics of intracerebral arterioles in clinical (Plasmodium falciparum) and experimental (Plasmodium berghei) cerebral malaria.
abstract: Spastic constriction of intracerebral arterioles was identified in clinical (P. falciparum) and experimental (P. berghei) cerebral malaria. Morphological criteria were used to characterize pathologically spastic constriction of arterioles. The significance of spastic constriction of intracerebral arterioles for microcirculatory disturbance in relation to development of cerebral malaria is discussed.
authors.affiliation: Department of Neurosurgery, University Hospital Nijmegen, The Netherlands.
authors.forename: T W
authors.initials: TW
authors.lastname: Polder
authors.forename: C R
authors.initials: CR
authors.lastname: Jerusalem
authors.forename: W M
authors.initials: WM
authors.lastname: Eling
mesh_terms: D000328:Adult; D000818:Animals; D001160:Arterioles / Q000473:pathology* / Q000648:ultrastructure; D001927:Brain Diseases / Q000473:pathology*; D002560:Cerebrovascular Circulation; D004730:Endothelium, Vascular / Q000473:pathology / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008288:Malaria / Q000473:pathology*; D008297:Male; D051379:Mice; D008854:Microscopy, Electron; D009131:Muscle, Smooth, Vascular / Q000473:pathology / Q000648:ultrastructure; D010962:Plasmodium berghei; D010963:Plasmodium falciparum; D011247:Pregnancy; D019966:Substance-Related Disorders