title: [Primary malignant lymphoma of the testis].
abstract: Among 715 patients with non-Hodgkin's lymphoma referred to this oncology center between 1973-1989, there were 7 (0.9%) with primary lymphoma of the testis. The mean age was 55 (range 23-78). The presenting symptom in all the 7 was testicular mass or swelling. 6 of them underwent inguinal orchiectomy and 1 had a testicular biopsy. The pathological subtype of the lymphoma in all 7 was the diffuse large cell type. The disease stage was IE in 3, IIE in 3 and IVE in 1. Only 1 had bilateral testicular involvement. 6 were treated primarily with various combinations of chemotherapy and 1 by radiotherapy. 3 developed recurrent disease (2 treated primarily with chemotherapy and 1 by radiotherapy) and died 14, 19 and 27 months, respectively, after diagnosis. 3 are alive with no evidence of recurrent lymphoma. Follow-up in an additional patient has been too short for evaluation. Primary testicular lymphoma is a relatively rare form of extranodal lymphoma. It has a tendency to early systemic progression and is potentially curable by aggressive combination chemotherapy.
authors.affiliation: Northern Israel Oncology Center and Dept. of Pathology, Rambam Medical Center, Haifa.
authors.forename: M
authors.initials: M
authors.lastname: Stein
authors.forename: N
authors.initials: N
authors.lastname: Haim
authors.forename: M
authors.initials: M
authors.lastname: Ben-Shahar
authors.forename: R
authors.initials: R
authors.lastname: Epelbaum
authors.forename: Y
authors.initials: Y
authors.lastname: Cohen
authors.forename: J
authors.initials: J
authors.lastname: Ben Arie
authors.forename: E
authors.initials: E
authors.lastname: Robinson
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009919:Orchiectomy; D013736:Testicular Neoplasms / Q000473:pathology / Q000628:therapy