Acute pulmonary effects of nitrogen dioxide exposure during exercise in competitive athletes.
The acute pulmonary responses of athletes after short-term exposure to ambient concentrations of NO2 during heavy exercise have been examined. Intercollegiate male athletes were screened for history of cardiac disease, respiratory disease, allergic conditions and extensive exposure to pollutants. After completion of serum IgE level determination, exercise tolerance test and methacholine challenge test with normal results, nine healthy subjects 18 to 23 years of age were exposed to filtered air and to 0.18 and 0.30 ppm NO2 for 30 min on different days while exercising on a treadmill. Pulmonary function parameters were measured before and after each exposure. In this study, no statistically significant changes were observed in FEV1, RT PEFR, and Vmax50% after exposure to 0.18 and 0.30 ppm NO2. For these selected healthy athletes, short-term exposure to ambient NO2 levels during heavy exercise does not affect adversely the pulmonary function.
Kim
S U
SU
School of Medicine, University of Washington, Seattle 98195.
Koenig
J Q
JQ
Pierson
W E
WE
Hanley
Q S
QS
D000328:Adult; D004305:Dose-Response Relationship, Drug; D015444:Exercise / Q000502:physiology*; D006801:Humans; D008168:Lung / Q000187:drug effects* / Q000502:physiology; D008176:Lung Volume Measurements; D008297:Male; D008452:Maximum Allowable Concentration; D009585:Nitrogen Dioxide / Q000008:administration & dosage / Q000009:adverse effects*; D012123:Pulmonary Ventilation / Q000187:drug effects; D014142:Track and Field
D009585:Nitrogen Dioxide