title: Endocrine crises. Hypophosphatemia and hyperphosphatemia.
abstract: Pathophysiology, clinical sequelae, and treatment for hypophosphatemia and hyperphosphatemia are discussed. Hypophosphatemia results from a variety of conditions including malnutrition, carbohydrate refeeding, acid-base disorders, and hormonal and drug effects. Patients suffering from severe hypophosphatemia may present with a variety of syndromes that can become detrimental and even life-threatening if this electrolyte depletion goes untreated. Hyperphosphatemia occurs because of increased extracellular phosphate load from either endogenous or exogenous sources or from a decrease in renal phosphate excretion. Left untreated, hyperphosphatemia can result in dangerous calciumphosphate precipitation into vital organs and tissues.
authors.affiliation: Department of Pharmacy, Mineral Area Regional Medical Center, Farmington, Missouri.
authors.forename: M P
authors.initials: MP
authors.lastname: Peppers
authors.forename: M
authors.initials: M
authors.lastname: Geheb
authors.forename: T
authors.initials: T
authors.lastname: Desai
mesh_terms: D000368:Aged; D005260:Female; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D008659:Metabolic Diseases / Q000209:etiology / Q000628:therapy; D010710:Phosphates / Q000097:blood* / Q000378:metabolism
chemical_list: D010710:Phosphates