Multiple sclerosis and narcolepsy: possible similar genetic susceptibility.
We have studied 2 patients with multiple sclerosis and narcolepsy. In both patients, the DR 2 histocompatibility antigen was positive. In each of the patients, the diagnosis of narcolepsy was confirmed by polygraphic testing.
Younger
D S
DS
Department of Neurology, Columbia-Presbyterian Medical Center, New York, NY 10032-3784.
Pedley
T A
TA
Thorpy
M J
MJ
D000328:Adult; D005260:Female; D020022:Genetic Predisposition to Disease; D015802:HLA-DR2 Antigen / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications* / Q000235:genetics / Q000276:immunology; D009290:Narcolepsy / Q000150:complications* / Q000235:genetics / Q000276:immunology; D012895:Sleep, REM
D015802:HLA-DR2 Antigen