Pain and measles, mumps, and rubella vaccination.
Seventy-seven children (mean age 44.2 months) were entered in a randomised double blind study to find out if two commonly used measles, mumps, and rubella (MMR) vaccines (Pluserix and MMR II) caused pain on injection. Pain was judged by the amount of crying. Infants given MMR II were 2.31 times more likely to cry than those given Pluserix.
Lyons
R
R
Eastern Health Board, Community Care Area 7, Aras Daimhin, Dublin, Republic of Ireland.
Howell
F
F
D002675:Child, Preschool; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008297:Male; D008458:Measles Vaccine / Q000009:adverse effects*; D022542:Measles-Mumps-Rubella Vaccine; D009108:Mumps Vaccine / Q000009:adverse effects*; D010146:Pain / Q000209:etiology*; D010147:Pain Measurement; D012411:Rubella Vaccine / Q000009:adverse effects*; D014611:Vaccination / Q000009:adverse effects*
D004338:Drug Combinations; D008458:Measles Vaccine; D022542:Measles-Mumps-Rubella Vaccine; D009108:Mumps Vaccine; D012411:Rubella Vaccine