title: Retinoblastoma. The long-term appearance of radiated intraocular tumors.
abstract: A retrospective analysis of 50 patients with retinoblastoma was undertaken to determine the appearance of intraocular retinoblastoma that had received external beam radiation a minimum of 10 years previously. Of the 91 tumors found in 59 eyes, 76 (84%) continued to be ophthalmoscopically visible after 10 years. The most common ophthalmoscopic appearance was a Type III regression pattern. The type of radiation regression pattern correlated with the pretreatment volume of the tumor. The largest tumors (mean, 10.0 disc diameter [dd]) became Type I regression patterns, whereas the smallest tumors (mean, 1.0 dd) completely disappeared. This represents the first long-term follow-up of the intraocular status of radiated retinoblastoma.
authors.affiliation: Ophthalmic Oncology Center, New York Hospital Cornell Medical Center, New York.
authors.forename: D H
authors.initials: DH
authors.lastname: Abramson
authors.forename: B
authors.initials: B
authors.lastname: McCormick
authors.forename: D
authors.initials: D
authors.lastname: Fass
authors.forename: R M
authors.initials: RM
authors.lastname: Ellsworth
authors.forename: C
authors.initials: C
authors.lastname: Gerardi
authors.forename: C A
authors.initials: CA
authors.lastname: Servodidio
authors.forename: A
authors.initials: A
authors.lastname: Romanella
mesh_terms: D002648:Child; D002675:Child, Preschool; D005134:Eye Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012074:Remission Induction; D012175:Retinoblastoma / Q000473:pathology / Q000532:radiotherapy*; D012189:Retrospective Studies