title: Bambuterol: a new long acting bronchodilating prodrug.
abstract: Bambuterol, a carbamate prodrug of terbutaline as a 5, 10, or 20-mg tablet, was given once every evening to patients with asthma in a randomized double-blind crossover study. Twenty milligrams improved pulmonary functions over 24 hours; 5 and 10 mg did not. Few side effects were observed.
authors.affiliation: Department of Pulmonary Disease, Regional Hospital, University of Trondheim, Norway.
authors.forename: J S
authors.initials: JS
authors.lastname: Vilsvik
authors.forename: O
authors.initials: O
authors.lastname: Langaker
authors.forename: G
authors.initials: G
authors.lastname: Persson
authors.forename: N
authors.initials: N
authors.lastname: Ringdal
authors.forename: J
authors.initials: J
authors.lastname: Schaanning
authors.forename: G
authors.initials: G
authors.lastname: Kvelstad
authors.forename: K
authors.initials: K
authors.lastname: Svensson
authors.forename: S
authors.initials: S
authors.lastname: Holthe
authors.forename: S
authors.initials: S
authors.lastname: Soliman
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D001249:Asthma / Q000188:drug therapy*; D001980:Bronchi / Q000187:drug effects / Q000502:physiology; D001993:Bronchodilator Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002940:Circadian Rhythm / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013726:Terbutaline / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use
chemical_list: D001993:Bronchodilator Agents; D013726:Terbutaline; C047766:bambuterol