title: Prostatic MR imaging performed with the three-point Dixon technique. Work in progress.
abstract: The three-point Dixon technique is an enhancement of the original Dixon method for the creation of water- and fat-proton magnetic resonance (MR) images. With the three-point Dixon technique, three measurements of phase shift at 0, pi, and -pi between the fat and water resonances are employed. Compensation for B0 inhomogeneity leads to an error-free decomposition into water- and fat-proton images; an accurate B0 map is also created. The lack of chemical shift artifact in the water- and fat-selective MR images permits the application of narrow receive bandwidth for the creation of T2-weighted images with a high signal-to-noise ratio. The technique was applied in vivo with four healthy subjects, seven patients with prostatic carcinoma, and one patient with benign prostatic hypertrophy and compared with conventional T2-weighted imaging. The three-point technique yielded images with improved definition of normal intraprostatic structures and zonal anatomy and, in some cases of prostatic carcinoma, provided better visualization of extraprostatic spread of tumor.
authors.affiliation: Department of Radiation Medicine, Massachusetts General Hospital, Boston.
authors.forename: B
authors.initials: B
authors.lastname: Tamler
authors.forename: F G
authors.initials: FG
authors.lastname: Sommer
authors.forename: G H
authors.initials: GH
authors.lastname: Glover
authors.forename: E
authors.initials: E
authors.lastname: Schneider
mesh_terms: D000328:Adult; D000368:Aged; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000033:anatomy & histology / Q000473:pathology*; D011471:Prostatic Neoplasms / Q000175:diagnosis*