Highly repeated short DNA sequences in the genome of Schistosoma mansoni recognized by a species-specific probe.
A cloned 0.64-kb DNA sequence of Schistosoma mansoni contains 121-bp tandem repeats and comprises at least 12% of the schistosomal genome of both sexes. It exhibits a high degree of species specificity upon hybridization with Schistosoma haematobium and Schistosoma magrebowiei DNA, and could detect with high sensitivity schistosomal DNA sequences in infected snails.
Hamburger
J
J
Kuvin Centre for the Study of Infectious and Tropical Diseases, Department of Parasitology, Hebrew University, Hadassah Medical School, Jerusalem, Israel.
Turetski
T
T
Kapeller
I
I
Deresiewicz
R
R
D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA / Q000032:analysis*; D015342:DNA Probes; D005260:Female; D008297:Male; D008969:Molecular Sequence Data; D009693:Nucleic Acid Hybridization; D012091:Repetitive Sequences, Nucleic Acid; D012550:Schistosoma mansoni / Q000235:genetics* / Q000302:isolation & purification; D012908:Snails / Q000469:parasitology; D013045:Species Specificity
D015342:DNA Probes; D004247:DNA