Neuroleptic malignant syndrome and Escherichia coli urosepsis.
Neuroleptic malignant syndrome is a rare but potentially life-threatening reaction to neuroleptic drugs. The syndrome develops rapidly, and may occur at the initiation of neuroleptic therapy or after long-term use; its pathogenesis is unclear. The signs and symptoms associated with the syndrome are hyperpyrexia, extreme muscle rigidity, an altered level of consciousness, and autonomic dysfunction. We describe a case of neuroleptic malignant syndrome in a patient who had Escherichia coli urosepsis caused by thioridazine.
Teglia
M Q
MQ
Department of Medicine, Winthrop-University Hospital, Mineola, NY 11501.
Hopkins
T T
TT
Cunha
B A
BA
D000368:Aged; D000369:Aged, 80 and over; D004927:Escherichia coli Infections / Q000150:complications*; D006801:Humans; D015994:Incidence; D008297:Male; D009459:Neuroleptic Malignant Syndrome / Q000150:complications* / Q000453:epidemiology; D013881:Thioridazine / Q000009:adverse effects*; D014552:Urinary Tract Infections / Q000150:complications / Q000382:microbiology*
D013881:Thioridazine