title: Potassium channels in aortic microsomes: conductance, selectivity, barium-induced blockage and subconductance states.
abstract: The activity of potassium channels of canine aortic sarcoplasmic reticulum was measured using the planar lipid bilayer-fusion technique. The channels have a conductance of 208 pS (400/100 mM K+ in cis/trans solutions) and potassium-to-sodium permeability ratio of 7.7 Ba2+ ions produced two main effects: one is the interruption of channel currents for tens to hundreds of milliseconds in a voltage-dependent manner, and the other is the appearance of a second conductance level with amplitude about 60% of the main level.
authors.affiliation: Academy of Sciences of the USSR, Institute of Cytology, Leningrad.
authors.forename: I B
authors.initials: IB
authors.lastname: Bezprozvanny
authors.forename: D S
authors.initials: DS
authors.lastname: Benevolensky
authors.forename: A P
authors.initials: AP
authors.lastname: Naumov
mesh_terms: D000818:Animals; D001011:Aorta; D001464:Barium; D002412:Cations; D004285:Dogs; D004553:Electric Conductivity; D008861:Microsomes / Q000737:chemistry; D009131:Muscle, Smooth, Vascular / Q000737:chemistry*; D011188:Potassium; D015221:Potassium Channels / Q000737:chemistry*; D012519:Sarcoplasmic Reticulum / Q000737:chemistry*; D012964:Sodium
chemical_list: D002412:Cations; D015221:Potassium Channels; D001464:Barium; D012964:Sodium; D011188:Potassium