title: Infected urine as a risk factor for postprostatectomy wound infection.
abstract: OBJECTIVE
  To study the relation of preoperative infected urine and postprostatectomy wound infection in patients with and without indwelling bladder catheters.
  
  
  METHODS
  Patients undergoing prostatectomy were evaluated for the presence of infected urine prior to prostatectomy and postoperative wound infection. They were further divided into patients with indwelling urinary catheter and catheter-free patients. All had received antibiotic prophylaxis.
  
  
  METHODS
  One hundred fifty consecutive patients undergoing open prostatectomy--mean age was 67 years; 100 patients with an indwelling catheter for a mean period of 50 days; 50 catheter-free patients.
  
  
  RESULTS
  Wound infection was found in 19 of 81 (23.5%) and in 6 of 69 (8.7%) patients with infected and sterile urine, respectively (p = .028). In patients with indwelling catheters prior to operation, wound infection was 22.4% when urine was infected and 8.3% when it was not. In patients without catheters, infected urine was associated with 40% of wound infections, as compared with 8.9% of wound infections in patients with sterile urine. Organisms obtained from infected wound and urine were identical in 84% of cases. These results were obtained despite antibiotic prophylaxis.
  
  
  CONCLUSIONS
  Wound infection has been demonstrated to be a postprostatectomy complication directly related to the presence of urinary infection at surgery; thus, elective prostatectomy should be deferred until urine becomes sterile.
authors.affiliation: Department of Urology, Sapir Medical Center, Kfar Sava, Israel.
authors.forename: S
authors.initials: S
authors.lastname: Richter
authors.forename: R
authors.initials: R
authors.lastname: Lang
authors.forename: F
authors.initials: F
authors.lastname: Zur
authors.forename: I
authors.initials: I
authors.lastname: Nissenkorn
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000892:Anti-Infective Agents, Urinary / Q000627:therapeutic use; D001437:Bacteriuria / Q000382:microbiology; D004755:Enterobacteriaceae / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011468:Prostatectomy / Q000379:methods*; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000209:etiology* / Q000517:prevention & control; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use; D014552:Urinary Tract Infections / Q000150:complications* / Q000188:drug therapy
chemical_list: D000892:Anti-Infective Agents, Urinary; D015662:Trimethoprim, Sulfamethoxazole Drug Combination