title: A defective proviral DNA with a 2.6-kb deletion of human immunodeficiency virus type 1 (HIV-1) in a persistently HIV-1 infected cell clone.
abstract: A cell line (H2-5) producing defective doughnut-shaped particles of human immunodeficiency virus type I (HIV-1) was found to contain proviral DNA with a large deletion of 2558 bases, corresponding to the 3' half of pol gene, the vif and vpr genes, and the 5' terminal of the tat gene.
authors.affiliation: Section of Serology, Hokkaido University, Sapporo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Imai
authors.forename: K
authors.initials: K
authors.lastname: Maotani-Imai
authors.forename: Y S
authors.initials: YS
authors.lastname: Shin
authors.forename: K
authors.initials: K
authors.lastname: Ikuta
authors.forename: S
authors.initials: S
authors.lastname: Suehiro
authors.forename: T
authors.initials: T
authors.lastname: Kurimura
authors.forename: S
authors.initials: S
authors.lastname: Kato
authors.forename: K
authors.initials: K
authors.lastname: Hirai
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D015152:Blotting, Northern; D015139:Blotting, Southern; D002460:Cell Line; D002872:Chromosome Deletion; D002999:Clone Cells; D004279:DNA, Viral / Q000235:genetics* / Q000302:isolation & purification; D003673:Defective Viruses / Q000235:genetics*; D005814:Genes, Viral; D015497:HIV-1 / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011533:Proviruses / Q000235:genetics*; D012367:RNA, Viral / Q000235:genetics / Q000302:isolation & purification; D015183:Restriction Mapping; D014158:Transcription, Genetic
chemical_list: D004279:DNA, Viral; D012367:RNA, Viral