Crystallization and preliminary X-ray investigation of recombinant human interleukin 4.
Crystals of recombinant human interleukin 4 have been grown from solutions of ammonium sulfate. The crystals are tetragonal, space-group P4(1)2(1)2 or P4(3)2(1)2; the unit cell axes are a = 92.2(1) A and c = 46.4(1) A. The crystals are stable to X-rays for at least three days and diffract beyond 2.8 A resolution. The crystals contain approximately 63% solvent, assuming there is one molecule in the asymmetric unit.
Cook
W J
WJ
Department of Pathology, University of Alabama, Birmingham 35294.
Ealick
S E
SE
Reichert
P
P
Hammond
G S
GS
Le
H V
HV
Nagabhushan
T L
TL
Trotta
P P
PP
Bugg
C E
CE
D006801:Humans; D015847:Interleukin-4 / Q000737:chemistry*; D011487:Protein Conformation; D011994:Recombinant Proteins / Q000737:chemistry; D014961:X-Ray Diffraction
D011994:Recombinant Proteins; D015847:Interleukin-4