In-vitro comparative activity of fluconazole and other antifungal agents against Blastoschizomyces capitatus.
Blastoschizomyces capitatus represents an emerging fungal pathogen in acute leukemia patients. The susceptibility to amphotericin B, 5-fluorocytosine, ketoconazole and fluconazole of nine clinical isolates was evaluated. A specific medium (high resolution medium) was used for testing fluconazole. This agent and 5-fluorocytosine were at least four- to eight-fold more active than amphotericin B and ketoconazole against all isolates but one.
Venditti
M
M
Patologia Medica II, Istituto di Clinica Medica VI, Università La Sapienza, Roma, Italy.
Posteraro
B
B
Morace
G
G
Martino
P
P
D000935:Antifungal Agents / Q000494:pharmacology*; D015725:Fluconazole / Q000494:pharmacology*; D005848:Geotrichum / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi / Q000187:drug effects*; D014250:Trichosporon / Q000187:drug effects
D000935:Antifungal Agents; D015725:Fluconazole