Routine imaging studies for the posttreatment surveillance of breast and colorectal carcinoma.
Current recommendations on follow-up procedures for patients who have been treated for cancer include imaging studies and other laboratory tests at relatively frequent intervals. At least two questions should be asked to evaluate the benefits of this practice for patients: Do frequent routine surveillance tests detect recurrences "earlier" in asymptomatic patients? and Does earlier treatment of these recurrences reduce morbidity or prolong survival? The practical import of surveillance with imaging and laboratory tests for recurrence in patients with cancer of the breast and colon is discussed. Reported autopsy data, findings at elective reoperation, and clinical data have been examined to ascertain the justification for routine periodic tests in the treated but asymptomatic patient. It is concluded that earlier detection of a local recurrence or of metastatic disease through periodic tests in the asymptomatic patient with breast or colon cancer rarely alters the treatment or the outcome. A notable exception is regular screening mammography following treatment for adenocarcinoma of the breast.
Kagan
A R
AR
Southern California Permanente Medical Group, Los Angeles.
Steckel
R J
RJ
D001859:Bone Neoplasms / Q000175:diagnosis / Q000556:secondary*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000401:mortality; D002272:Carcinoembryonic Antigen / Q000097:blood; D002423:Cause of Death; D015179:Colorectal Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000401:mortality; D005189:False Positive Reactions; D005500:Follow-Up Studies; D006801:Humans; D008207:Lymphatic Metastasis; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000401:mortality
D002272:Carcinoembryonic Antigen