title: Clinical use of metronidazole in horses: 200 cases (1984-1989).
abstract: Case records of 200 horses treated with metronidazole were reviewed. Horses were treated for respiratory tract infections (90 cases), peritonitis or abdominal abscess (39 cases), celiotomy (49 cases), orthopedic infections (6 cases), and miscellaneous soft tissue infections (16 cases). Bacteria of the genus Bacteroides were most prevalent (55 of 167 anaerobic isolates). Metronidazole was always used in combination with other antimicrobial drugs. Only 4 of the 200 horses had signs of adverse effects associated with metronidazole treatment. Those 4 horses had poor appetite that resolved when metronidazole treatment was discontinued.
authors.affiliation: Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, New Bolton Center, Kennett Square 19348.
authors.forename: R W
authors.initials: RW
authors.lastname: Sweeney
authors.forename: C R
authors.initials: CR
authors.lastname: Sweeney
authors.forename: J
authors.initials: J
authors.lastname: Weiher
mesh_terms: D000818:Animals; D001421:Bacteria, Anaerobic; D001424:Bacterial Infections / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary*; D001442:Bacteroides Infections / Q000188:drug therapy / Q000662:veterinary; D004359:Drug Therapy, Combination; D005260:Female; D005767:Gastrointestinal Diseases / Q000188:drug therapy / Q000662:veterinary; D006734:Horse Diseases / Q000188:drug therapy*; D006736:Horses; D008297:Male; D008795:Metronidazole / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D012141:Respiratory Tract Infections / Q000188:drug therapy / Q000662:veterinary; D012189:Retrospective Studies
chemical_list: D008795:Metronidazole