title: L-156,602, a C5a antagonist with a novel cyclic hexadepsipeptide structure from Streptomyces sp. MA6348. Fermentation, isolation and structure determination.
authors.affiliation: Merck Sharp & Dohme Research Laboratories, Rahway, N.J. 07065.
authors.forename: O D
authors.initials: OD
authors.lastname: Hensens
authors.forename: R P
authors.initials: RP
authors.lastname: Borris
authors.forename: L R
authors.initials: LR
authors.lastname: Koupal
authors.forename: C G
authors.initials: CG
authors.lastname: Caldwell
authors.forename: S A
authors.initials: SA
authors.lastname: Currie
authors.forename: A A
authors.initials: AA
authors.lastname: Haidri
authors.forename: C F
authors.initials: CF
authors.lastname: Homnick
authors.forename: S S
authors.initials: SS
authors.lastname: Honeycutt
authors.forename: S M
authors.initials: SM
authors.lastname: Lindenmayer
authors.forename: C D
authors.initials: CD
authors.lastname: Schwartz
mesh_terms: D002850:Chromatography, Gel; D015936:Complement C5a / Q000037:antagonists & inhibitors*; D005285:Fermentation; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008968:Molecular Conformation; D015394:Molecular Structure; D010456:Peptides, Cyclic / Q000096:biosynthesis* / Q000737:chemistry / Q000302:isolation & purification; D013302:Streptomyces / Q000378:metabolism*; D014961:X-Ray Diffraction
chemical_list: D010456:Peptides, Cyclic; C051485:PD 124966; D015936:Complement C5a