title: Tretinoin treatment of photodamaged skin. Cosmesis through medical therapy.
abstract: Topical tretinoin is an effective therapy for the treatment of photodamaged skin. Clinically, patients experience decreased wrinkling, improved texture, and pinkening of sallow skin. However, the changes induced by topical tretinoin extend beyond simple cosmesis. Microscopic, ultrastructural, and biochemical alterations indicate that topical tretinoin is a significant medical therapy. Its successful use requires the guidance of an experienced physician.
authors.affiliation: Department of Dermatology, Emory University Medical School, Atlanta, Georgia.
authors.forename: J S
authors.initials: JS
authors.lastname: Weiss
authors.forename: C N
authors.initials: CN
authors.lastname: Ellis
authors.forename: M T
authors.initials: MT
authors.lastname: Goldfarb
authors.forename: J J
authors.initials: JJ
authors.lastname: Voorhees
mesh_terms: D003358:Cosmetics / Q000627:therapeutic use; D006801:Humans; D007642:Keratosis / Q000188:drug therapy; D010787:Photosensitivity Disorders / Q000188:drug therapy*; D015595:Skin Aging; D014212:Tretinoin / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D003358:Cosmetics; D014212:Tretinoin