title: Osteochondrodystrophy (ocd): a new autosomal recessive mutation in the mouse.
abstract: Osteochondrodystrophy (ocd) is a new autosomal recessive mouse mutation characterized by a short, slightly domed head, reduced body size, disproportionately shortened long bones of the legs, supination of the forefeet, and short thickened tail. Histologically, the epiphyses are thinner than normal. The columnar organization of the proliferative zone of cartilage is disorderly, with pleomorphic and occasionally necrotic chondrocytes. Osteochondrodystrophy has been mapped to a position near the centromere of mouse chromosome (Chr) 19.
authors.affiliation: Jackson Laboratory, Bar Harbor, ME 04609.
authors.forename: H O
authors.initials: HO
authors.lastname: Sweet
authors.forename: R T
authors.initials: RT
authors.lastname: Bronson
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000473:pathology; D003433:Crosses, Genetic; D004392:Dwarfism / Q000235:genetics* / Q000473:pathology; D005260:Female; D005808:Genes, Recessive; D008040:Genetic Linkage; D008297:Male; D051379:Mice; D009154:Mutation; D010641:Phenotype