Endocrine crises. Hypophosphatemia and hyperphosphatemia.
Pathophysiology, clinical sequelae, and treatment for hypophosphatemia and hyperphosphatemia are discussed. Hypophosphatemia results from a variety of conditions including malnutrition, carbohydrate refeeding, acid-base disorders, and hormonal and drug effects. Patients suffering from severe hypophosphatemia may present with a variety of syndromes that can become detrimental and even life-threatening if this electrolyte depletion goes untreated. Hyperphosphatemia occurs because of increased extracellular phosphate load from either endogenous or exogenous sources or from a decrease in renal phosphate excretion. Left untreated, hyperphosphatemia can result in dangerous calciumphosphate precipitation into vital organs and tissues.
Peppers
M P
MP
Department of Pharmacy, Mineral Area Regional Medical Center, Farmington, Missouri.
Geheb
M
M
Desai
T
T
D000368:Aged; D005260:Female; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D008659:Metabolic Diseases / Q000209:etiology / Q000628:therapy; D010710:Phosphates / Q000097:blood* / Q000378:metabolism
D010710:Phosphates