title: Comparison of topical Xylocaine with placebo as a local anesthetic in colposcopic biopsies.
abstract: Colposcopically directed biopsies cause discomfort for the patient. Topical lidocaine (Xylocaine) had routinely been applied to the cervix before biopsies performed at the colposcopy clinic of the Ottawa General Hospital. A prospective, single-blind trial was performed to compare the effect of topical Xylocaine with that of a placebo. Patients in both groups experienced discomfort; the median pain score in both groups was equal, and statistical analysis of the results by the Mann-Whitney test showed no difference between the two treatment groups.
authors.affiliation: Department of Obstetrics and Gynecology, Ottawa General Hospital, Ont.
authors.forename: M
authors.initials: M
authors.lastname: Prefontaine
authors.forename: M
authors.initials: M
authors.lastname: Fung-Kee-Fung
authors.forename: D
authors.initials: D
authors.lastname: Moher
mesh_terms: D000758:Anesthesia; D001706:Biopsy; D002584:Cervix Uteri / Q000473:pathology*; D003127:Colposcopy; D005260:Female; D006801:Humans; D008012:Lidocaine; D010147:Pain Measurement; D011446:Prospective Studies
chemical_list: D008012:Lidocaine