Penetration of cefonicid into serum, salpinges, cervix and vaginal tissue.
Cefonicid is a new cephalosporin that, given in adequate concentrations is able to kill some pathogens such as Gram-positive cocci and many Enterobacteriaceae. In this study we have evaluated 40 patients receiving 1 g of cefonicid i.m. at various times before abdominal or vaginal hysterectomy. The results of the present study indicate that a single dose of 1 g of cefonicid given intramuscularly is useful as prophylaxis and treatment of gynecological infections.
Goisis
M
M
Department of Obstetrics and Gynecology, General Hospital, Lodi Milan, Italy.
Grossi
F
F
Soncini
R
R
Gusmitta
A
A
D015790:Cefonicid / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D002584:Cervix Uteri / Q000378:metabolism*; D005187:Fallopian Tubes / Q000378:metabolism*; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008875:Middle Aged; D014018:Tissue Distribution; D014621:Vagina / Q000378:metabolism*
D015790:Cefonicid