Rosai-Dorfman disease of the uterine cervix.
A case of Rosai-Dorfman disease of the uterine cervix is described. The disease is characterized by a mixed chronic inflammatory cell infiltrate in which histiocytic cells predominate. A characteristic feature is the presence within many of the histiocytic cells of engulfed, but undamaged, lymphocytes. Rosai-Dorfman disease is of unknown etiology and pursues a benign course. The disease can occur at a wide variety of extranodal sites, but this appears to be the first reported instance of female genital tract involvement.
Murray
J
J
Department of Pathology, South African Institute for Medical Research, Johannesburg.
Fox
H
H
D000328:Adult; D005260:Female; D006644:Histiocytes / Q000473:pathology; D015618:Histiocytosis, Sinus / Q000473:pathology*; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D002577:Uterine Cervical Diseases / Q000473:pathology*