Serum TAG 72 levels in different human carcinomas.
Since December 1988, we have measured the TAG 72 serum levels in 326 patients with different carcinomas, especially breast, gastrointestinal and ovarian, using a RIA kit. With a cut-off value of 5 U/mL, a specificity of 100% in the controls and an overall sensitivity of 22% in the neoplastic patients was obtained, with the highest positivities in ovarian (63%) and gastric (58%) carcinomas. Therefore, TAG 72 can be associated with other tumor markers for these latter neoplasms.
Correale
M
M
Clinical Chemistry Laboratory, RIA Unit, Oncology Institute of Bari, Italy.
Abbate
I
I
Gargano
G
G
Garrubba
M
M
Muncipinto
A
A
Addabbo
L
L
Colangelo
D
D
D000951:Antigens, Neoplasm / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood*; D001943:Breast Neoplasms / Q000097:blood; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000097:blood; D006023:Glycoproteins / Q000097:blood*; D006801:Humans; D009369:Neoplasms / Q000097:blood*; D010051:Ovarian Neoplasms / Q000097:blood
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D006023:Glycoproteins; C047052:tumor-associated antigen 72