title: The administration of transcranial electric treatment for affective disturbances therapy in alcoholic patients.
abstract: In a double blind placebo-controlled investigation it was shown that transcranial electric treatment (TET), comprising the combination of a constant current with a pulse current of square impulses of 70-80 Hz is an effective method to correct affective disturbances (anxiety, depression) in alcoholic patients. The medical effects of TET are accompanied by changes in the metabolism of GABA and monoamines, but not of beta-endorphin, and also by a decrease in the latency of alpha-rhythm appearance after closing of the eyes.
authors.affiliation: Leningrad Regional Dispensary of Narcology, U.S.S.R.
authors.forename: E M
authors.initials: EM
authors.lastname: Krupitsky
authors.forename: A M
authors.initials: AM
authors.lastname: Burakov
authors.forename: G F
authors.initials: GF
authors.lastname: Karandashova
authors.lastname: Katsnelson JaS
authors.forename: V P
authors.initials: VP
authors.lastname: Lebedev
authors.lastname: Grinenko AJa
authors.lastname: Borodkin JuS
mesh_terms: D000328:Adult; D000437:Alcoholism / Q000201:enzymology / Q000523:psychology / Q000534:rehabilitation*; D000513:Alpha Rhythm; D001008:Anxiety Disorders / Q000201:enzymology / Q000523:psychology / Q000534:rehabilitation*; D001143:Arousal / Q000502:physiology; D003866:Depressive Disorder / Q000201:enzymology / Q000523:psychology / Q000534:rehabilitation*; D004599:Electric Stimulation Therapy / Q000379:methods*; D000431:Ethanol / Q000009:adverse effects*; D006801:Humans; D007527:Isoenzymes / Q000097:blood; D008995:Monoamine Oxidase / Q000097:blood; D010556:Personality Tests; D013375:Substance Withdrawal Syndrome / Q000201:enzymology / Q000523:psychology / Q000534:rehabilitation*; D005680:gamma-Aminobutyric Acid / Q000097:blood
chemical_list: D007527:Isoenzymes; D000431:Ethanol; D005680:gamma-Aminobutyric Acid; D008995:Monoamine Oxidase