title: Cross-protective immunity and the serological classification system for Bacteroides nodosus.
abstract: The relationship between the serological classification system for serogroup B and for serogroup H of Bacteroides nodosus and cross-protection between subgroups within these serogroups was examined. Protection against ovine footrot following vaccination was achieved against other subgroup strains provided sufficient cross-reactive antibody was induced by shared pilus antigens. Within serogroup B, better cross-protection against one subgroup was obtained with a pili vaccine than a whole cell vaccine which correlated with higher pilus antibody titres induced by the former. For serogroup H, a lack of cross-protection and serological reactivity between subgroups was demonstrated, which indicates that the prototype strain of subgroup H2 should be designated a new serogroup.
authors.affiliation: CSIRO Division of Animal Health, Animal Health Research Laboratory, Parkville, Victoria.
authors.forename: D J
authors.initials: DJ
authors.lastname: Stewart
authors.forename: J A
authors.initials: JA
authors.lastname: Vaughan
authors.forename: T C
authors.initials: TC
authors.lastname: Elleman
authors.forename: P A
authors.initials: PA
authors.lastname: Hoyne
authors.forename: K J
authors.initials: KJ
authors.lastname: Burns
authors.forename: J H
authors.initials: JH
authors.lastname: Dufty
mesh_terms: D000372:Agglutination Tests; D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis*; D001428:Bacterial Vaccines / Q000276:immunology*; D001439:Bacteroides / Q000145:classification* / Q000276:immunology; D003429:Cross Reactions; D005260:Female; D005535:Foot Rot / Q000517:prevention & control*; D011897:Random Allocation; D012703:Serotyping; D012756:Sheep; D012757:Sheep Diseases / Q000517:prevention & control*; D014611:Vaccination / Q000662:veterinary
chemical_list: D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines