title: Iodine-125 interstitial implants as salvage therapy for recurrent gynecologic malignancies.
abstract: Twenty-one patients with the diagnosis of recurrent gynecologic pelvic malignancy from various primary sites were treated with iodine-125 (I-125) interstitial implants. Eighteen of these patients had been treated with a combination of surgery and radiation therapy for their primary malignancies and 90% had responded. Seventy-five percent had complete local responses. The overall survival time, volume-response relationship, and complications are discussed and the radioresponse of various histologic types is presented.
authors.affiliation: Department of Obstetrics and Gynecology, Loyola University Medical Center, Maywood, IL 60153.
authors.forename: S K
authors.initials: SK
authors.lastname: Sharma
authors.forename: H
authors.initials: H
authors.lastname: Forgione
authors.forename: J H
authors.initials: JH
authors.lastname: Isaacs
mesh_terms: D001918:Brachytherapy / Q000009:adverse effects; D002277:Carcinoma / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D005833:Genital Neoplasms, Female / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery; D015996:Survival Rate
chemical_list: D007457:Iodine Radioisotopes