The resolution of preeclampsia-related thrombocytopenia.
The average time until the resolution of thrombocytopenia, which as a part of HELLP syndrome accompanies 4-16% of cases of severe preeclampsia, has not been defined previously. We followed 25 patients with severe preeclampsia, platelet counts below 100,000/microL, and elevated liver enzymes until their platelet counts returned to levels above 100,000/microL. Among severe preeclamptics who did not receive platelet transfusions, the average time from delivery to the resolution of thrombocytopenia was 60 hours, and all had platelet counts above 100,000/microL by 95 hours. Seven patients were followed after their platelet counts exceeded 340,000/microL; all showed a rebound phenomenon, with platelet counts reaching values of 413,000-871,000/microL.
Neiger
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R
Department of Obstetrics and Gynecology, Memorial Medical Center, Savannah, Georgia.
Contag
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Coustan
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DR
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D010976:Platelet Count; D049590:Postpartum Period; D011225:Pre-Eclampsia / Q000150:complications*; D011247:Pregnancy; D012075:Remission, Spontaneous; D013921:Thrombocytopenia / Q000209:etiology / Q000503:physiopathology*; D013997:Time Factors