Immunoreactivity of endogenous digitalis-like factors.
Highly specific antisera produced against cardenolide (digoxin) and bufodienolide (bufalin) may bind the endogenous ouabain-displacing compounds from human urine. However, it should be borne in mind that the degree of recognition by the antisera significantly differ between two ouabain-displacing compounds.
Goto
A
A
Second Department of Internal Medicine, University of Tokyo, Japan.
Yamada
K
K
Ishii
M
M
Sugimoto
T
T
Yoshioka
M
M
D000937:Antigen-Antibody Reactions; D001667:Binding, Competitive; D001798:Blood Proteins / Q000276:immunology* / Q000652:urine; D002018:Bufanolides / Q000276:immunology; D002298:Cardenolides; D003429:Cross Reactions; D004077:Digoxin / Q000276:immunology; D006801:Humans; D066298:In Vitro Techniques; D010042:Ouabain / Q000378:metabolism; D012503:Saponins
D001798:Blood Proteins; D002018:Bufanolides; D002298:Cardenolides; D012503:Saponins; C034504:digoxin-like factors; D010042:Ouabain; D004077:Digoxin; C022777:bufalin