Paternal alcohol consumption affects grooming response in rat offspring.
Grooming behavior in response to novelty and water immersion was examined in rat offspring sired by males consuming liquid alcohol diets containing 35%, 17.5% or 0% ethanol-derived calories (EDC). In the first study, offspring were tested at 35-38 days of age under conditions of lights on or off. Offspring in the 35% EDC group groomed less than controls. Lighting conditions did not affect grooming significantly. In the second study, animals were immersed in a water bath for 15 seconds and were then placed in the same observation chambers. As in the previous study, animals sired by alcohol-consuming fathers groomed considerably less than controls. These results were interpreted as suggesting offspring sired by alcohol-consuming fathers have a blunted response to conditions which spontaneously elicit behavior like grooming or ambulation.
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Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000633:toxicity*; D005260:Female; D005333:Fetus / Q000187:drug effects*; D006120:Grooming / Q000187:drug effects*; D008297:Male; D051381:Rats; D012737:Sex Factors
D000431:Ethanol