title: Bone mass in healthy children: measurement with quantitative DXA.
abstract: Dual-energy x-ray bone densitometry was used to study the lumbar vertebral bone mass in 218 healthy children (134 girls and 84 boys) aged 1-19 years. Vertebral bone mass increased with weight, age, and pubertal Tanner stage. Results of multiple regression analyses showed that Tanner stage and weight were the best predictive indicators of bone mass and bone mineral density. The influences of age, sex, race, physical activity, and diet were not significant when Tanner stage and weight were controlled. Two tables of predictive intervals for lumbar vertebral bone mineral density in healthy children (one based on Tanner stage and weight; the other, on age and weight) are presented. With normative data now available for use with this precise technique, clinicians can better detect abnormal bone mineral density in children and evaluate changes in mineralization over time.
authors.affiliation: Department of Pediatrics, Columbus Children's Hospital, College of Medicine, Ohio State University 43205.
authors.forename: R N
authors.initials: RN
authors.lastname: Southard
authors.forename: J D
authors.initials: JD
authors.lastname: Morris
authors.forename: J D
authors.initials: JD
authors.lastname: Mahan
authors.forename: J R
authors.initials: JR
authors.lastname: Hayes
authors.forename: M A
authors.initials: MA
authors.lastname: Torch
authors.forename: A
authors.initials: A
authors.lastname: Sommer
authors.forename: W B
authors.initials: WB
authors.lastname: Zipf
mesh_terms: D015502:Absorptiometry, Photon; D000293:Adolescent; D015519:Bone Density; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012016:Reference Values; D012044:Regression Analysis; D013131:Spine / Q000000981:diagnostic imaging*