title: Gonadotroph adenoma of the pituitary mimicking a prolactinoma.
abstract: In a 41-year-old woman with mild hyperprolactinemia and amenorrhea, preoperative hormonal and neuroradiological findings suggested the diagnosis of a macroprolactinoma. She underwent transsphenoidal surgery since the tumor size had not changed in spite of bromocriptine administration for 5 months. Consequently, this case was diagnosed as a female-type gonadotroph adenoma on the basis of its characteristic ultrastructural features including a honeycomb Golgi complex, even though endocrinological and immunohistochemical findings were not those of a typical gonadotroph adenoma.
authors.affiliation: Division of Neurosurgery, Toranomon Hospital, Tokyo, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Yamada
authors.forename: E
authors.initials: E
authors.lastname: Horvath
authors.forename: K
authors.initials: K
authors.lastname: Kovacs
authors.forename: T
authors.initials: T
authors.lastname: Aiba
authors.forename: T
authors.initials: T
authors.lastname: Shimizu
authors.forename: Y
authors.initials: Y
authors.lastname: Shishiba
authors.forename: M
authors.initials: M
authors.lastname: Hara
mesh_terms: D000236:Adenoma / Q000175:diagnosis* / Q000648:ultrastructure; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000648:ultrastructure; D015175:Prolactinoma / Q000175:diagnosis*