Anticardiolipin antibodies: a study of frequency in TIA and stroke.
We undertook a prospective study of consecutive patients to determine the frequency of elevated IgG and IgM anticardiolipin antibodies in transient ischemic attack and ischemic stroke and found elevated IgG antibodies in 8.2% (9 of 110) and IgM in 9.1% (10 of 110), only the former being significantly greater than in a healthy control population. We suggest that anticardiolipin screening be concentrated on the young.
Hess
D C
DC
Department of Neurology, Medical College of Georgia, Augusta.
Krauss
J
J
Adams
R J
RJ
Nichols
F T
FT
Zhang
D
D
Rountree
H A
HA
D000906:Antibodies / Q000032:analysis*; D002308:Cardiolipins / Q000276:immunology*; D002561:Cerebrovascular Disorders / Q000097:blood / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D002546:Ischemic Attack, Transient / Q000097:blood / Q000276:immunology*; D008875:Middle Aged; D010314:Partial Thromboplastin Time
D000906:Antibodies; D002308:Cardiolipins; D007074:Immunoglobulin G