Bone and cementum as stromal features in Pindborg tumor.
A case of calcifying epithelial odontogenic tumor (CEOT) occurring in the left mandible of a 50-yr-old man was characterized by the presence of large masses of calcified collagen. Calcified amyloid acted as the nucleus for the deposition of this material. Because of the close association between both types of calcified material, it is presumed that the calcified amyloid is an inductive stimulus for the stromal cells to differentiate towards production of a collagenous matrix destined to calcify and resembling cementum. The stromal component of CEOT thus seems to be just as odontogenic as the epithelium is.
Slootweg
P J
PJ
University Hospital, Department of Pathology, Utrecht, The Netherlands.
D000682:Amyloid; D001842:Bone and Bones; D002114:Calcinosis / Q000473:pathology; D003094:Collagen; D003739:Dental Cementum; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000473:pathology*; D008875:Middle Aged; D009808:Odontogenic Tumors / Q000473:pathology*
D000682:Amyloid; D003094:Collagen