Encephalopathy and neuropathy following ingestion of a Chinese herbal broth containing podophyllin.
Two patients developed podophyllin intoxication following ingestion of a broth of the Chinese herb guijiu. The neurological manifestations are described and the pathology of the peripheral neuropathy is fully documented with ultrastructural and quantitative studies.
Ng
T H
TH
Department of Pathology, University of Hong Kong.
Chan
Y W
YW
Yu
Y L
YL
Chang
C M
CM
Ho
H C
HC
Leung
S Y
SY
But
P P
PP
D000328:Adult; D001921:Brain / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology*; D001927:Brain Diseases / Q000139:chemically induced* / Q000473:pathology / Q000503:physiopathology; D005500:Follow-Up Studies; D006723:Hong Kong; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D009046:Motor Neurons / Q000502:physiology; D009422:Nervous System Diseases / Q000139:chemically induced / Q000473:pathology / Q000503:physiopathology*; D009431:Neural Conduction; D009475:Neurons, Afferent / Q000502:physiology; D009498:Neurotoxins; D009900:Optic Nerve / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology*; D010525:Peripheral Nerves / Q000187:drug effects / Q000503:physiopathology; D008517:Phytotherapy; D011033:Podophyllin / Q000506:poisoning*
D009498:Neurotoxins; D011033:Podophyllin