Genetic activity of the human carcinogen sulphur mustard towards Salmonella and the mouse bone marrow.
Sulphur mustard is clearly mutagenic to the repair-proficient (uvrB+) strain G46 of S. typhimurium. It is also a micronucleus-inducing agent to the mouse bone marrow. These data strengthen the database indicating that most human carcinogens are genotoxic.
Ashby
J
J
ICI Central Toxicology Laboratory, Macclesfield, Ches., Great Britain.
Tinwell
H
H
Callander
R D
RD
Clare
N
N
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects*; D002273:Carcinogens; D006801:Humans; D051379:Mice; D015162:Micronucleus Tests; D009151:Mustard Gas / Q000633:toxicity*; D009152:Mutagenicity Tests; D012486:Salmonella typhimurium / Q000235:genetics*; D013045:Species Specificity
D002273:Carcinogens; D009151:Mustard Gas