title: Clinical evaluation of stenosis of the carotid bifurcation with magnetic resonance angiographic techniques.
abstract: We evaluated the images of 60 carotid artery bifurcations in 31 patients suspected to have carotid artery disease who underwent invasive carotid angiography and combined two-dimensional, phase-sensitive and a gradient-echo magnetic resonance angiography. The phase scans consisted of seven serial projections that were obtained at 20 degrees intervals (11.0 minutes) around the carotid bifurcation; the gradient-echo (GRASS) scans were composed of 11 axial images (2.4 minutes) acquired through the bifurcation. The two magnetic resonance angiographic techniques yielded complementary pieces of information and were used together to compare magnetic resonance angiography with invasive angiography. Comparison of magnetic resonance and invasive angiograms of the 60 carotid arteries shows that the sensitivity (86%) and specificity (92%) of the magnetic resonance angiographic techniques we used to diagnose clinically significant carotid stenosis approach but do not reach those of invasive angiography.
authors.affiliation: Department of Diagnostic Radiology, University of Rochester Medical Center, NY.
authors.forename: D K
authors.initials: DK
authors.lastname: Kido
authors.forename: R J
authors.initials: RJ
authors.lastname: Panzer
authors.forename: J
authors.initials: J
authors.lastname: Szumowski
authors.forename: J
authors.initials: J
authors.lastname: Hollander
authors.forename: L M
authors.initials: LM
authors.lastname: Ketonen
authors.forename: A
authors.initials: A
authors.lastname: Monajati
authors.forename: K
authors.initials: K
authors.lastname: Ouriel
authors.forename: J V
authors.initials: JV
authors.lastname: Manzione
authors.forename: C L
authors.initials: CL
authors.lastname: Dumoulin
authors.forename: S P
authors.initials: SP
authors.lastname: Souza
mesh_terms: D000368:Aged; D002339:Carotid Arteries / Q000473:pathology; D002340:Carotid Artery Diseases / Q000175:diagnosis*; D003251:Constriction, Pathologic / Q000175:diagnosis; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity