title: HLA-D antigens and Paget's disease of bone.
abstract: HLA-A, -B, -C, -DR, and -DQ antigens were determined in 25 Ashkenazi Jews with Paget's disease of bone. HLA-DR2 was more frequent in the Pagetic patients compared with 57 healthy controls of the same ethnic origin. This finding concurs with a previous report and raises the possibility that HLA-DR2 may be associated with Paget's disease of bone, probably by predisposing the bone cells to viral infection.
authors.affiliation: Department of Medicine, Hadassah University Hospital, Jerusalem, Israel.
authors.forename: J
authors.initials: J
authors.lastname: Foldes
authors.forename: S
authors.initials: S
authors.lastname: Shamir
authors.forename: C
authors.initials: C
authors.lastname: Brautbar
authors.forename: L
authors.initials: L
authors.lastname: Schermann
authors.forename: J
authors.initials: J
authors.lastname: Menczel
mesh_terms: D005260:Female; D006681:HLA-D Antigens / Q000302:isolation & purification*; D015802:HLA-DR2 Antigen / Q000302:isolation & purification; D006801:Humans; D008297:Male; D010001:Osteitis Deformans / Q000208:ethnology / Q000276:immunology*
chemical_list: D006681:HLA-D Antigens; D015802:HLA-DR2 Antigen