Brain MRI in obsessive-compulsive disorder.
Magnetic resonance imaging (MRI) brain scans were performed on 12 patients with obsessive-compulsive disorder and 12 healthy controls. Measurements of the area of the head of the caudate nucleus, cingulate gyrus thickness, intracaudate/frontal horn ratio, and area of the corpus callosum did not differ between the two groups. These limited data do not support the presence of a consistent gross brain structural abnormality in obsessive-compulsive disorder. Further studies using other anatomic measurements and other brain structural imaging techniques are warranted.
Kellner
C H
CH
Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston 29425.
Jolley
R R
RR
Holgate
R C
RC
Austin
L
L
Lydiard
R B
RB
Laraia
M
M
Ballenger
J C
JC
D000328:Adult; D000368:Aged; D001921:Brain / Q000473:pathology*; D001931:Brain Mapping; D002421:Caudate Nucleus / Q000473:pathology; D003337:Corpus Callosum / Q000473:pathology; D005260:Female; D006179:Gyrus Cinguli / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000175:diagnosis* / Q000473:pathology / Q000523:psychology; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis* / Q000473:pathology / Q000523:psychology