title: Cytologic diagnosis of adenovirus bronchopneumonia.
abstract: The recognition of adenovirus-induced cytopathic changes in tracheal aspirates of two 7-month-old infants is reported. The smears showed cells containing nuclear inclusions with radiated strands ("rosette" cells), large homogeneously-staining nuclei ("smudge" cells) and nuclei with a "honeycomb" appearance. These findings appear to be distinctive for bronchopulmonary adenovirus infection, suggesting that the cytologic examination of tracheal aspirates may be a simple and cost-saving method for making an accurate diagnosis of this disease.
authors.affiliation: Department of Pathology, Children's Hospital, La Plata, Argentina.
authors.forename: M N
authors.initials: MN
authors.lastname: Bayón
authors.forename: R
authors.initials: R
authors.lastname: Drut
mesh_terms: D000258:Adenovirus Infections, Human / Q000175:diagnosis / Q000473:pathology*; D001344:Autopsy; D001996:Bronchopneumonia / Q000175:diagnosis / Q000382:microbiology* / Q000473:pathology; D003581:Cytodiagnosis; D005260:Female; D006801:Humans; D007223:Infant; D008168:Lung / Q000382:microbiology / Q000473:pathology