title: Identification of the genomic region determining serotype specificity of Vibrio cholerae 01.
abstract: A 2.1-kb genomic region responsible for Ogawa serotype specificity of Vibrio cholerae 01 was identified by cosmid cloning and recombinant plasmid experiments. The plasmid carrying this region derived from Ogawa type Vibrio cholerae NIH 41 coded for a specific protein of 27 kD, and was found to convert serotype specificity from Inaba to Ogawa when co-introduced into the Escherichia coli cells harboring a cloned 20-kilobase genomic DNA fragment of Inaba type Vibrio cholerae 35A3.
authors.affiliation: Department of Bacteriolog, Faculty of Medicine, Juntendo University, Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ito
authors.forename: Y
authors.initials: Y
authors.lastname: Ohshita
authors.forename: T
authors.initials: T
authors.lastname: Nakamoto
authors.forename: K
authors.initials: K
authors.lastname: Hiramatsu
authors.forename: T
authors.initials: T
authors.lastname: Yokota
mesh_terms: D000942:Antigens, Bacterial / Q000235:genetics*; D001426:Bacterial Proteins / Q000235:genetics; D003001:Cloning, Molecular; D003360:Cosmids; D004269:DNA, Bacterial / Q000235:genetics; D005798:Genes, Bacterial; D011994:Recombinant Proteins / Q000276:immunology; D015183:Restriction Mapping; D014734:Vibrio cholerae / Q000235:genetics* / Q000276:immunology
chemical_list: D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D004269:DNA, Bacterial; D011994:Recombinant Proteins