title: A new case of IgE myeloma.
abstract: A new case of IgE myeloma is described. A 77-year-old woman presented with bone pain and fatigue. Serum protein analysis revealed a paraprotein of the IgE kappa type; bone marrow aspirate and immunofluorescence confirmed the diagnosis; ultrastructural examination showed immature plasma cells. Treatment with prednisone, melphalan, cyclophosphamide and interferon alfa did not produce any improvement and the patient died 5 months after diagnosis. The patient's clinical and laboratory data are compared with those of IgE myeloma cases reported in the literature.
authors.affiliation: Institute of Internal Medicine, Infectious Diseases, Immunopathology, University of Milan, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Invernizzi
authors.forename: G
authors.initials: G
authors.lastname: Monti
authors.forename: A G
authors.initials: AG
authors.lastname: Caviglia
authors.forename: P
authors.initials: P
authors.lastname: Meroni
authors.forename: C
authors.initials: C
authors.lastname: Zanussi
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D009101:Multiple Myeloma / Q000276:immunology*
chemical_list: D007073:Immunoglobulin E