title: Brucella optic neuritis.
abstract: A 13-year-old girl sustained acute blindness of the left eye with bilateral papilledema. An extensive search for a cause revealed only acute Brucella infection, documented by blood cultures that were positive for Brucella and a rise and fall of Brucella agglutination titer. Computed tomographic scan of the orbit revealed thickening and irregularity of the optic nerve. The patient was treated with anti-Brucella therapy and high-dose corticosteroids, with resultant complete recovery and return of visual acuity, disappearance of papilledema, and return of the optic nerve to its normal shape and thickness.
authors.affiliation: Division of Rheumatology and Immunology, King Fahad Hospital, Riyadh, Saudi Arabia.
authors.forename: M
authors.initials: M
authors.lastname: Abd Elrazak
mesh_terms: D000293:Adolescent; D002006:Brucellosis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D005260:Female; D006801:Humans; D009902:Optic Neuritis / Q000382:microbiology*; D011241:Prednisone / Q000627:therapeutic use; D012529:Saudi Arabia / Q000453:epidemiology; D013307:Streptomycin / Q000627:therapeutic use; D013752:Tetracycline / Q000627:therapeutic use
chemical_list: D013752:Tetracycline; D011241:Prednisone; D013307:Streptomycin