Transcriptional enhancer in the vicinity of a replication origin within the 5' region of the chicken alpha-globin gene domain.
A transcriptional enhancer is located near a replication origin within an upstream area of chicken domain of alpha-globin genes. Minimal region possessing enhancer properties is located about 4 kb upstream from the alpha-pi gene. Addition of the neighbouring 500 base-pair DNA fragment, including the constitutive DNase I hypersensitive site, increases the enhancer activity approximately twofold.
Razin
S V
SV
Institute of Molecular Biology, Academy of Sciences of the USSR, Moscow.
Vassetzky
Y S
YS
Kvartskhava
A I
AI
Grinenko
N F
NF
Georgiev
G P
GP
D000818:Animals; D001483:Base Sequence; D002645:Chickens; D004261:DNA Replication; D004742:Enhancer Elements, Genetic; D005796:Genes; D005914:Globins / Q000235:genetics*; D008969:Molecular Sequence Data; D014158:Transcription, Genetic
D005914:Globins