Comparison of fifteen production batches of house dust mite extract (Dermatophagoides pteronyssinus).
An important measurement of quality of allergenic extracts is the batch to batch uniformity. Using different methods of protein and immunobiochemical analysis, we could demonstrate, that 15 production batches of house dust mite Dermatophagoides pteronyssinus extract prepared during the course of 4 years from different lots of the source material, (purified whole mite bodies) showed reproducible data.
Wahl
R
R
Department for Research and Development of Allergen Extract Preparations, Allergopharma Joachim Ganzer KG, Hamburg, Germany.
Oliver
J D
JD
Hauck
P
P
Schultze-Werninghaus
G
G
Paap
A
A
D000485:Allergens / Q000032:analysis*; D000818:Animals; D039741:Antigens, Dermatophagoides; D004391:Dust / Q000032:analysis*; D004591:Electrophoresis, Polyacrylamide Gel; D015151:Immunoblotting; D007122:Immunoelectrophoresis; D008925:Mites / Q000032:analysis*; D009584:Nitrogen / Q000032:analysis; D011506:Proteins / Q000032:analysis; D011852:Radioallergosorbent Test; D012882:Skin Tests
D000485:Allergens; D039741:Antigens, Dermatophagoides; D004391:Dust; D011506:Proteins; D009584:Nitrogen