Calcium deprivation increases NaCl intake of Fischer-344 rats.
Fischer-344 rats fed Ca2(+)-deficient diet for 63 days increased intake of 0.3 M NaCl solution from control levels of approximately 8 ml/day to greater than 60 ml/day. During the same period, rats fed Na(+)-deficient diet drank approximately 11 ml/day. These results indicate that Fischer-344 rats, which generally spurn NaCl, drink large amounts of it when Ca2+ deprived.
Tordoff
M G
MG
Monell Chemical Senses Center, Philadelphia, PA 19104-3308.
D000818:Animals; D002118:Calcium / Q000502:physiology*; D006706:Homeostasis / Q000502:physiology; D008297:Male; D051381:Rats; D011916:Rats, Inbred F344; D012084:Renin-Angiotensin System / Q000502:physiology; D012965:Sodium Chloride / Q000008:administration & dosage*; D014882:Water-Electrolyte Balance / Q000502:physiology*
D012965:Sodium Chloride; D002118:Calcium