title: [Treatment of chronic lymphocytic leukemia in relation to clinico- morphological characteristics of the disease].
abstract: Marrow histomorphometry was performed in 73 untreated chronic lymphoid leukemia (CLL) sufferers. Follow-up results are available for 36 of them: 25 treated and 11 untreated with chemotherapy. The method of marrow histomorphometry allows recognition of three CLL forms: diffuse, diffuse-focal and focal; helps to determine indications to chemotherapy, assess its efficacy, prognosticate the disease course; is more reliable than clinical and laboratory findings.
authors.forename: V A
authors.initials: VA
authors.lastname: Tumakov
authors.forename: K M
authors.initials: KM
authors.lastname: Abdulkadyrov
authors.forename: V I
authors.initials: VI
authors.lastname: Rugal'
authors.forename: M V
authors.initials: MV
authors.lastname: Karpenkov
authors.forename: V V
authors.initials: VV
authors.lastname: Ved'
authors.forename: A F
authors.initials: AF
authors.lastname: Brodovskiĭ
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001853:Bone Marrow / Q000187:drug effects* / Q000473:pathology; D003520:Cyclophosphamide / Q000008:administration & dosage; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000097:blood / Q000188:drug therapy* / Q000473:pathology; D007958:Leukocyte Count / Q000187:drug effects; D008198:Lymph Nodes / Q000187:drug effects* / Q000473:pathology; D008214:Lymphocytes / Q000187:drug effects* / Q000473:pathology; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage; D011379:Prognosis; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D003520:Cyclophosphamide; D011241:Prednisone