title: The histidines of the iron-uptake regulation protein, Fur.
abstract: There are 12 histidine residues/molecule in the iron-uptake regulation protein (Fur). Here we examine their pH dependence using proton nuclear magnetic resonance spectroscopy. The histidines have widely spread acid dissociation constants but we can not offer a simple explantation for their complicated behaviour.
authors.affiliation: Inorganic Chemistry Laboratory, University of Oxford, UK.
authors.forename: T
authors.initials: T
authors.lastname: Saito
authors.forename: D
authors.initials: D
authors.lastname: Duly
authors.forename: R J
authors.initials: RJ
authors.lastname: Williams
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000737:chemistry* / Q000378:metabolism; D004926:Escherichia coli / Q000378:metabolism; D006639:Histidine; D007501:Iron / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008962:Models, Theoretical; D011487:Protein Conformation; D012097:Repressor Proteins / Q000737:chemistry* / Q000378:metabolism
chemical_list: D001426:Bacterial Proteins; D012097:Repressor Proteins; C068477:ferric uptake regulating proteins, bacterial; D006639:Histidine; D007501:Iron