Epidemiology of HDV infection in Japan.
Anti-HD antibody was not detected in 342 patients with acute type B hepatitis including 8 patients with fulminant hepatitis. Anti-HD antibody was detected in 10 out of 1668 HBV carriers. The overall prevalence was 0.59 percent. Two (0.34%) out of 586 ASC, 3 (0.43%) out of 690 patients with CH and 5 (1.47%) out of 338 patients with LC were positive for anti-HD antibody. No anti-HD antibody was detected in sera of 54 patients with HCC. The prevalence of anti-HD antibody was relatively high in patients with LC, however, HDV infection was relatively rare in Japan and it does not always play a major role in progression of liver disease. The prevalence of HDV infection in HBV carriers has not changed in Japan during the last ten years (1.3% vs. 1.49%).
Mitamura
K
K
Department of Infectious Diseases, Institute of Medical Science, University of Tokyo, Japan.
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D002353:Carrier State; D005260:Female; D006508:Hepatitis Antibodies / Q000097:blood; D006509:Hepatitis B / Q000150:complications*; D006514:Hepatitis B Surface Antigens / Q000097:blood; D003699:Hepatitis D / Q000150:complications / Q000453:epidemiology*; D003698:Hepatitis Delta Virus / Q000276:immunology; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012737:Sex Factors
D006508:Hepatitis Antibodies; D006514:Hepatitis B Surface Antigens