title: Alteration of cartilagenous proteoglycan in psoriasis.
abstract: Articular tissue was obtained at surgery for a femoral neck fracture in a patient with psoriasis without arthritis. The proteoglycan of the cartilage of the sample was analysed biochemically. Normal cartilage is known to produce two types of proteoglycan monomers (fast- and slow-sedimenting groups), which are distinguishable by density-gradient ultracentrifugation. In the psoriatic cartilage analysed in the present study, it was shown that the former group was absent and only the latter group remained.
authors.affiliation: Department of Orthopaedic Surgery, Osaka City University Medical School, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Yutani
authors.forename: T
authors.initials: T
authors.lastname: Kono
authors.forename: M
authors.initials: M
authors.lastname: Ishii
authors.forename: M
authors.initials: M
authors.lastname: Chanoki
authors.forename: Y
authors.initials: Y
authors.lastname: Chanoki
authors.forename: K
authors.initials: K
authors.lastname: Asada
authors.forename: A
authors.initials: A
authors.lastname: Shimazu
authors.forename: T
authors.initials: T
authors.lastname: Hamada
mesh_terms: D002358:Cartilage, Articular / Q000378:metabolism*; D046508:Culture Techniques; D006801:Humans; D008297:Male; D008875:Middle Aged; D011509:Proteoglycans / Q000378:metabolism*; D011565:Psoriasis / Q000378:metabolism*; D013462:Sulfur Radioisotopes / Q000378:metabolism
chemical_list: D011509:Proteoglycans; D013462:Sulfur Radioisotopes