Membranoproliferative glomerulonephritis associated with sickle cell disease in two siblings.
The cases of two brothers with sickle-cell anemia complicated by the nephrotic syndrome and membranoproliferative glomerulonephritis are presented. The literature related to this infrequent association is reviewed and possible explanations for the occurrence of the latter in two brothers are discussed.
Iskandar
S S
SS
Department of Pathology, Bowman Gray School of Medicine, Wake Forest University, Winston Salem, North Carolina 27103.
Morgann
R G
RG
Browning
M C
MC
Lorentz
W B
WB
D000293:Adolescent; D000755:Anemia, Sickle Cell / Q000235:genetics*; D005455:Fluorescent Antibody Technique; D005500:Follow-Up Studies; D015432:Glomerulonephritis, Membranoproliferative / Q000150:complications* / Q000473:pathology; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D008297:Male; D009504:Neutrophils / Q000473:pathology