title: XLMR genes: update 1990.
abstract: We have identified 39 X-linked conditions in which mental retardation seems to be the primary characteristic, although pathogenesis is unknown. These conditions can be subdivided into syndromal and non-syndromal, depending on the existence of a recognizable pattern of minor anomalies and/or malformations, or lack thereof. Seventeen genes have been regionally mapped onto the X chromosome. However, in 14 instances the data were derived from a single family and most lod scores were less than 3.0.
authors.affiliation: Istituto di Genetica Umana A. Gemelli School of Medicine, U.C.S.C., Rome, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Neri
authors.forename: F
authors.initials: F
authors.lastname: Gurrieri
authors.forename: A
authors.initials: A
authors.lastname: Gal
authors.forename: H A
authors.initials: HA
authors.lastname: Lubs
mesh_terms: D002874:Chromosome Mapping; D000013:Congenital Abnormalities / Q000235:genetics; D005260:Female; D005819:Genetic Markers; D006801:Humans; D008607:Intellectual Disability / Q000145:classification / Q000235:genetics*; D008297:Male; D014960:X Chromosome
chemical_list: D005819:Genetic Markers