title: [Development of antihypertensive drug consumption in the Toulouse University Regional Hospital Center from 1981 to 1989].
abstract: Eighties were characterized by the introduction of two new pharmacological class of antihypertensive drugs [converting enzyme inhibitors (CEI) and calcium channel blockers] and the publication of several large scale antihypertensive trials. The consumption of antihypertensive drugs at the Toulouse Universitary Hospital was evaluated during the ten last years. Total consumption remained stable until 1985 (560,000 pinch units) and raised to 650,000 in 1988. This number decreased to 580,000 in 1989. Consumption of diuretics remained stable during these years whereas beta-blocking agents slightly decreased. The global increase of prescription was explained by the introduction of CEI and a marked rise in calcium channel blockers from 1986. In contrast, consumption of central antihypertensive drugs crushed from 1982 to equal vasodilators (direct + alpha-blocking agents) in 1989.
authors.affiliation: Service de Pharmacologie Médicale et Clinique, Centre Hospitalier Universitaire, Faculté de Médecine, Toulouse.
authors.forename: F
authors.initials: F
authors.lastname: Rolland
authors.forename: J
authors.initials: J
authors.lastname: Lafont
authors.forename: J L
authors.initials: JL
authors.lastname: Montastruc
authors.forename: P
authors.initials: P
authors.lastname: Montastruc
mesh_terms: D000959:Antihypertensive Agents / Q000145:classification / Q000627:therapeutic use*; D004363:Drug Utilization / Q000639:trends; D005602:France; D006785:Hospitals, University; D006801:Humans
chemical_list: D000959:Antihypertensive Agents