Gonadotroph adenoma of the pituitary mimicking a prolactinoma.
In a 41-year-old woman with mild hyperprolactinemia and amenorrhea, preoperative hormonal and neuroradiological findings suggested the diagnosis of a macroprolactinoma. She underwent transsphenoidal surgery since the tumor size had not changed in spite of bromocriptine administration for 5 months. Consequently, this case was diagnosed as a female-type gonadotroph adenoma on the basis of its characteristic ultrastructural features including a honeycomb Golgi complex, even though endocrinological and immunohistochemical findings were not those of a typical gonadotroph adenoma.
Yamada
S
S
Division of Neurosurgery, Toranomon Hospital, Tokyo, Japan.
Horvath
E
E
Kovacs
K
K
Aiba
T
T
Shimizu
T
T
Shishiba
Y
Y
Hara
M
M
D000236:Adenoma / Q000175:diagnosis* / Q000648:ultrastructure; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000648:ultrastructure; D015175:Prolactinoma / Q000175:diagnosis*