Mycosis fungoides: cutaneous T-cell lymphoma.
Most patients with mycosis fungoides are between 40 and 60 years of age. The disease has three clinical stages: (1) the premycotic, or patch, stage, consisting of macular, scaling, faint pink to red pruritic patches, usually on unexposed surfaces; (2) the mycotic, or plaque, stage, consisting of reddish, purple-brown plaques, often annular in shape and symmetric in distribution, and (3) the tumor stage, consisting of red-brown to violaceous, dome-shaped, firm tumors with a predilection for the face and body folds. The Sézary syndrome is a leukemic variant. Treatment depends on the extent of disease and includes topical or systemic chemotherapy, radiotherapy and psoralen plus long-wave ultraviolet light therapy.
Zaim
M T
MT
Case Western Reserve University School of Medicine, Cleveland, Ohio.
Grinkemeyer
M D
MD
D000328:Adult; D001706:Biopsy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000145:classification / Q000175:diagnosis / Q000473:pathology*; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D011379:Prognosis; D012751:Sezary Syndrome / Q000473:pathology; D012878:Skin Neoplasms / Q000145:classification / Q000175:diagnosis / Q000473:pathology*