title: Effects of etidocaine administered epidurally on changes in somatosensory evoked potentials after dermatomal stimulation.
abstract: The effect of lumbar epidural anesthesia with similar volumes (approximately 20 ml) of 1% and 1.5% etidocaine on early (less than 0.5 seconds) somatosensory evoked potentials (SEPs) to electrical stimulation of the S1, L1, and T10 dermatomes was examined in two groups of ten patients in a randomized, double-blind study. Level of analgesia to pinprick was T7.7 +/- 0.9 in the 1% group and T6.6 +/- 0.6 in the 1.5% group and all patients had total motor block. Despite similar analgesia to pinprick, SEP amplitude was more reduced in the 1.5% group, in which SEPs were abolished in all patients at the L1 level.
authors.affiliation: Department of Anesthesiology, Copenhagen University Medical School, Hvidovre Hospital, Denmark.
authors.forename: C
authors.initials: C
authors.lastname: Lund
authors.forename: O B
authors.initials: OB
authors.lastname: Hansen
authors.forename: H
authors.initials: H
authors.lastname: Kehlet
authors.forename: T
authors.initials: T
authors.lastname: Mogensen
authors.forename: S
authors.initials: S
authors.lastname: Qvitzau
mesh_terms: D000328:Adult; D000767:Anesthesia, Epidural; D004311:Double-Blind Method; D004558:Electric Stimulation; D005041:Etidocaine / Q000008:administration & dosage / Q000494:pharmacology*; D005073:Evoked Potentials, Somatosensory / Q000187:drug effects*; D006801:Humans; D011897:Random Allocation; D012867:Skin / Q000294:innervation*; D013223:Statistics as Topic
chemical_list: D005041:Etidocaine