Effects of high-intensity cycle exercise on sympathoadrenal-medullary response patterns.
Plasma proenkephalin peptide F immunoreactivity and catecholamines were examined on separate days in nine healthy males before and after maximal exercise to exhaustion at four intensities [36, 55, 73, and 100% of maximal leg power (MLP)] by use of a computerized cycle ergometer. The mean duration of 36, 55, 73, and 100% MLP was 3.31, 0.781, 0.270, and 0.1 min, respectively. All intensities were greater than those eliciting peak O2 uptake for the individual subjects. Blood samples were obtained before, immediately after exercise, and 5 and 15 min after exercise. Significant (P less than 0.05) increases in plasma peptide F immunoreactivity (i.e., from mean resting value of 0.18 to 0.43 pmol/ml) were observed immediately after exercise at 36% MLP. Significant increases in plasma epinephrine were observed immediately after exercise at 36% MLP (i.e., from mean resting value of 2.22 to 3.11 pmol/ml) and 55% MLP (i.e., from mean resting value of 1.67 to 2.98 pmol/ml) and 15 min after exercise at 100% MLP (i.e., from mean resting value of 1.92 to 3.88 pmol/ml). Significant increases for plasma norepinephrine were observed immediately after exercise (36, 55, 73, and 100% MLP), 5 min after exercise (36, 55, and 73% MLP), and 15 min after exercise (36% MLP). Increases in whole blood lactate were observed at all points after exercise for 36, 55, and 73% MLP and 5 min after exercise for 100% MLP. These data show that brief high-intensity exercise results in differential response patterns of catecholamines and proenkephalin peptide F immunoreactivity.
Kraemer
W J
WJ
Exercise Physiology Division, US Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760-5007.
Patton
J F
JF
Knuttgen
H G
HG
Hannan
C J
CJ
Kettler
T
T
Gordon
S E
SE
Dziados
J E
JE
Fry
A C
AC
Frykman
P N
PN
Harman
E A
EA
D000313:Adrenal Medulla / Q000502:physiology*; D000328:Adult; D004744:Enkephalin, Methionine / Q000031:analogs & derivatives / Q000097:blood; D004837:Epinephrine / Q000097:blood; D015444:Exercise / Q000502:physiology*; D006801:Humans; D007773:Lactates / Q000097:blood; D019344:Lactic Acid; D008297:Male; D009638:Norepinephrine / Q000097:blood; D011498:Protein Precursors / Q000097:blood; D013564:Sympathetic Nervous System / Q000502:physiology*
D007773:Lactates; D011498:Protein Precursors; D019344:Lactic Acid; D004744:Enkephalin, Methionine; C036452:peptide F; D009638:Norepinephrine; D004837:Epinephrine