title: Aspergillus otomastoiditis in acquired immunodeficiency syndrome.
abstract: The diagnosis and therapy of fungal infection in the paranasal sinuses of the immunocompromised host, including those with acquired immunodeficiency syndrome (AIDS), has been discussed in recent literature. However, only limited reports have been presented on otologic infection in AIDS patients. A review of 26 such patients with otologic disease included no cases of fungal otopathology. Our recent experience with two patients with Aspergillus otomastoiditis is presented. The extent of fungal infection in these cases was early-stage in one patient and late-stage in the other. The case histories, management, and outcomes are presented to provide insight into this previously unreported complication of AIDS.
authors.affiliation: Department of Otolaryngology--Head and Neck Surgery, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106.
authors.forename: M
authors.initials: M
authors.lastname: Strauss
authors.forename: E
authors.initials: E
authors.lastname: Fine
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D001228:Aspergillosis / Q000209:etiology*; D001232:Aspergillus fumigatus; D005260:Female; D006801:Humans; D008297:Male; D008417:Mastoiditis / Q000209:etiology*; D010033:Otitis Media / Q000209:etiology*