title: A high-performance system for automation of the polymerase chain reaction.
abstract: A high-performance PCR system has been developed which reduces the time required for PCR, increases the throughput, reduces reagent consumption and ensures reproducibility of amplification. Integration of sophisticated temperature control with optimally designed vessels has resulted in an amplification system which produces unique benefits. These include rapid amplification, the elimination of the need for oil, even for small volumes, and a microplate format which provides liquid handling automation benefits.
authors.affiliation: Perkin-Elmer Corporation, Norwalk, CT 06859-0251.
authors.forename: L
authors.initials: L
authors.lastname: Haff
authors.forename: J G
authors.initials: JG
authors.lastname: Atwood
authors.forename: J
authors.initials: J
authors.lastname: DiCesare
authors.forename: E
authors.initials: E
authors.lastname: Katz
authors.forename: E
authors.initials: E
authors.lastname: Picozza
authors.forename: J F
authors.initials: JF
authors.lastname: Williams
authors.forename: T
authors.initials: T
authors.lastname: Woudenberg
mesh_terms: D001331:Automation; D016133:Polymerase Chain Reaction / Q000295:instrumentation / Q000379:methods*; D015203:Reproducibility of Results; D013696:Temperature; D013997:Time Factors