Effectiveness of ofloxacin in the treatment of Chlamydia trachomatis and Neisseria gonorrhoeae cervical infection.
Forty patients with cervical infection caused by Chlamydia trachomatis were treated with ofloxacin (20) or doxycycline (20). Ofloxacin was successful in eradicating C. trachomatis from all 20 (100%) patients. Doxycycline was effective in 18 of 20 (90%) patients. Three patients had a concomitant cervical gonococcal infection. All three were successfully treated: one with ofloxacin and two with doxycycline. Ofloxacin, 300 mg, taken twice daily for 7 days, is effective in eradicating endocervical C. trachomatis infection.
Faro
S
S
Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, TX 77030.
Martens
M G
MG
Maccato
M
M
Hammill
H A
HA
Roberts
S
S
Riddle
G
G
D000293:Adolescent; D000328:Adult; D002690:Chlamydia Infections / Q000188:drug therapy* / Q000382:microbiology; D002692:Chlamydia trachomatis; D004318:Doxycycline / Q000627:therapeutic use; D004341:Drug Evaluation; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans; D015242:Ofloxacin / Q000627:therapeutic use*; D011897:Random Allocation; D002575:Uterine Cervicitis / Q000188:drug therapy* / Q000382:microbiology
D015242:Ofloxacin; D004318:Doxycycline