The primary structure of human H-protein of the glycine cleavage system deduced by cDNA cloning.
A full-length cDNA encoding the human H-protein of the glycine cleavage system has been isolated from a lambda gt11 human fetal liver cDNA library. The cDNA insert was 1091 base pairs with an open reading frame of 519 base pairs which encoded a 125-amino acid mature human H-protein with a 48-amino acid presequence. Human H-protein is 97%, 86%, and 46% identical to the bovine, chicken, and pea H-protein, respectively.
Fujiwara
K
K
Institute for Enzyme Research, University of Tokushima, Japan.
Okamura-Ikeda
K
K
Hayasaka
K
K
Motokawa
Y
Y
D000594:Amino Acid Oxidoreductases; D000595:Amino Acid Sequence; D000818:Animals; D001482:Base Composition; D001483:Base Sequence; D002352:Carrier Proteins / Q000096:biosynthesis / Q000235:genetics*; D002417:Cattle; D002645:Chickens; D003001:Cloning, Molecular; D004247:DNA / Q000737:chemistry*; D007887:Fabaceae / Q000235:genetics; D015698:Genomic Library; D005998:Glycine / Q000378:metabolism; D050961:Glycine Decarboxylase Complex H-Protein; D050841:Glycine Dehydrogenase (Decarboxylating); D006801:Humans; D006868:Hydrolysis; D008099:Liver / Q000737:chemistry*; D008969:Molecular Sequence Data; D010946:Plants, Medicinal; D015183:Restriction Mapping; D012689:Sequence Homology, Nucleic Acid
D002352:Carrier Proteins; D050961:Glycine Decarboxylase Complex H-Protein; D004247:DNA; D000594:Amino Acid Oxidoreductases; D050841:Glycine Dehydrogenase (Decarboxylating); D005998:Glycine