[An epidemiological study of the cancer morbidity in persons having industrial contact with carcinogenic amino compounds].
Epidemiology of cancer was studied in a group of aniline-dye industry workers. Cancer morbidity in those directly exposed to betanaphthylamine and benzidine was 1.8 and 2 times the expected one for males and females, respectively (p less than 0.05). Bladder cancer morbidity was many times the expected one for both males and females; it did not involve prevalence in male morbidity generally observed for this site. Primary multiple malignant tumors were more frequently registered in females. Stomach and lung cancer morbidity was increased in males (p less than 0.05). Also, prophylactic measures should be taken at factories using amino compounds which are suspected to be carcinogenic for man.
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D015081:2-Naphthylamine / Q000009:adverse effects*; D000814:Aniline Compounds; D001560:Benzidines / Q000009:adverse effects*; D002617:Chemical Industry; D015331:Cohort Studies; D004396:Coloring Agents; D006801:Humans; D009369:Neoplasms / Q000139:chemically induced / Q000453:epidemiology*; D009784:Occupational Diseases / Q000139:chemically induced / Q000453:epidemiology*; D016273:Occupational Exposure / Q000009:adverse effects*; D011446:Prospective Studies; D012737:Sex Factors; D014586:USSR / Q000453:epidemiology
D000814:Aniline Compounds; D001560:Benzidines; D004396:Coloring Agents; D015081:2-Naphthylamine