title: Alcohol effects on the morphometric development of the subfornical organ and area postrema of the albino mouse.
abstract: We have studied the development of the nuclear sizes of ependymocytes and neurons of two circumventricular organs of the male alcoholic mouse: the Subfornical Organ (SFO) and the Area Postrema (AP), comparing the results with a control group. The global volume of both centers was also studied. The results show that the SFO, a structure related to the control of fluid balance, responds to alcoholism with an increase of the global volume. This increase could be related to the variations of salt-water balance and/or blood pressure in chronic alcoholism. However, the size of cell nuclei in the SFO is not affected. In contrast, the AP responds to chronic alcoholism like other nervous centres, with a decrease of the nuclear size of its cells. The global volume of AP does not change.
authors.affiliation: Departamento de Anatomia, Facultad de Medicina, Universidad de La Laguna, Tenerife, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Castañeyra-Perdomo
authors.forename: M M
authors.initials: MM
authors.lastname: Perez-Delgado
authors.forename: G
authors.initials: G
authors.lastname: Meyer
authors.forename: E
authors.initials: E
authors.lastname: Carmona-Calero
authors.forename: H
authors.initials: H
authors.lastname: Perez-Gonzalez
authors.forename: T
authors.initials: T
authors.lastname: Gonzalez-Hernandez
authors.forename: R
authors.initials: R
authors.lastname: Ferres-Torres
mesh_terms: D000437:Alcoholism / Q000473:pathology; D000818:Animals; D002552:Cerebral Ventricles / Q000187:drug effects* / Q000473:pathology; D000431:Ethanol / Q000633:toxicity*; D051379:Mice; D009474:Neurons / Q000187:drug effects; D013356:Subfornical Organ / Q000187:drug effects* / Q000473:pathology
chemical_list: D000431:Ethanol