title: Tumors of the central nervous system. Improvement in outcome through a multimodality approach.
abstract: More children with CNS tumors will continue to be cured of their neoplasms as a result of improved surgical, radiotherapeutic, and chemotherapeutic intervention. The complex problems seen in these patients mandate their treatment at academic centers actively involved in therapeutic investigations and capable of providing comprehensive multidisciplinary care.
authors.affiliation: Department of Pediatrics, Duke University Medical Center, Durham, North Carolina.
authors.forename: H S
authors.initials: HS
authors.lastname: Friedman
authors.forename: M
authors.initials: M
authors.lastname: Horowitz
authors.forename: W J
authors.initials: WJ
authors.lastname: Oakes
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001921:Brain / Q000187:drug effects / Q000528:radiation effects; D001932:Brain Neoplasms / Q000473:pathology / Q000628:therapy*; D002648:Child; D003131:Combined Modality Therapy; D006801:Humans; D011379:Prognosis; D011879:Radiotherapy Dosage