title: [Antibiotic therapy of acute dysentery in children with immunologic deficiency conditions].
abstract: One hundred children with acute Sonnei and flexneri dysentery were followed up with respect to the infection process and main immunity indices. In 32 children the immunity indices were physiological (group 1) and in 68 children secondary immune deficiency was observed (group 2). The children were treated with aminoglycoside antibiotics and prodigiozan and it was stated that the time of recovery in the children with immune deficiency was longer by 5.2 days as compared to that in the children without immune deficiency. In the children with immune deficiency the combined use of one of the aminoglycosides, prodigiozan and lysozyme, led to a reduction of the host immunological reactivity and recovery within the same periods as those recorded for children with the physiological immunity status. It is recommended to use the antibiotic combination with prodigiozan and lysozyme in the treatment of all the forms of dysentery in children with secondary immune deficiency.
authors.forename: I A
authors.initials: IA
authors.lastname: Vereshchagin
authors.forename: O D
authors.initials: OD
authors.lastname: Zhuravleva
mesh_terms: D000208:Acute Disease; D000276:Adjuvants, Immunologic; D000293:Adolescent; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D002648:Child; D004405:Dysentery, Bacillary / Q000188:drug therapy* / Q000209:etiology / Q000276:immunology; D006801:Humans; D009894:Opportunistic Infections / Q000188:drug therapy* / Q000209:etiology / Q000276:immunology; D010585:Phagocyte Bactericidal Dysfunction / Q000150:complications / Q000188:drug therapy*; D011354:Prodigiozan / Q000008:administration & dosage*; D012763:Shigella flexneri; D012764:Shigella sonnei
chemical_list: D000276:Adjuvants, Immunologic; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D011354:Prodigiozan
vernacular_title: Antibiotikoterapiia ostroĭ dizenterii pri immunodefitsitnom sostoianii organizma u deteĭ.