title: Sjögren-like pluriglandular exocrine insufficiency after drug-induced toxic epidermal necrolysis.
abstract: We present the case of a patient that progressively developed xerophthalmia, xerostomia, cutaneous xerosis and exocrine pancreatic insufficiency 3 months after metamizole-induced toxic epidermal necrolysis. Though the association of Sjögren's syndrome and exocrine pancreatic impairment is well established, the Sjögren-like syndrome after drug-induced toxic epidermal necrolysis in association with such a wide exocrine glandular insufficiency has not been previously described, to our knowledge.
authors.affiliation: Department of Medicine, Hospital Ramón y Cajal, University of Alcalá de Henares, Madrid, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Sabán
authors.forename: J R
authors.initials: JR
authors.lastname: Pais
authors.forename: J L
authors.initials: JL
authors.lastname: Rodríguez
authors.forename: D
authors.initials: D
authors.lastname: Boixeda
mesh_terms: D004177:Dipyrone / Q000009:adverse effects; D010188:Exocrine Pancreatic Insufficiency / Q000209:etiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000209:etiology*; D013262:Stevens-Johnson Syndrome / Q000150:complications* / Q000209:etiology; D014985:Xerophthalmia / Q000209:etiology; D014987:Xerostomia / Q000209:etiology
chemical_list: D004177:Dipyrone