Mania in the elderly: a 5-7 year follow-up.
A 5-7 year follow-up study of elderly individuals hospitalized on an acute psychiatric inpatient service for bipolar disorder, manic phase, demonstrates that the prognosis of mania has improved in the past 30 years. A majority of those hospitalized for mania are alive and living independently 5 years after hospitalization. However, eight of 25 (32%) patients have experienced a decline in Mini-Mental State Exam score to below 24, suggesting a clinically significant cognitive disorder. Mortality rates were higher in the manic group than expected from population norms. Compared to a group of similarly aged individuals hospitalized for unipolar depression, patients with bipolar disorder had an earlier age of onset and a lesser likelihood of being rehospitalized.
Dhingra
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U
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Rabins
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PV
D000368:Aged; D001714:Bipolar Disorder / Q000209:etiology / Q000401:mortality*; D003072:Cognition Disorders / Q000209:etiology; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000150:complications; D011379:Prognosis; D011569:Psychiatric Status Rating Scales; D012008:Recurrence; D015996:Survival Rate