title: Nutritional factors and pancreatic cancer: a case-control study from south-west Poland.
abstract: A population-based case-control study of diet and pancreatic cancer has been conducted in the Opole Voivodeship region in Poland, using 110 cases and 195 controls. A full diet history was used to estimate the daily intake of calories, fat, protein, carbohydrate, cholesterol, retinol, vitamin C, and fibre. There is a strong positive association with the intake of cholesterol with relative risks of 1.90, 3.77, and 4.31 for the 3 upper quartiles compared with the lowest (p, trend = less than 0.01). An inverse association was seen with vitamin C intake, with corresponding relative risks of 1.10, 0.30, and 0.37 (p, trend = less than 0.01). Weak inverse associations were seen with the intake of retinol and fibre. There is evidence of an inverse association with fat intake, particularly unsaturated fats, and of a positive association with the intake of carbohydrate and to a lesser extent, protein. These results further support the potential importance of dietary factors in the aetiology of cancer of the pancreas.
authors.affiliation: Cancer Control and Epidemiology Department, Maria Sklodowska-Curie Memorial Cancer Center, Warsaw, Poland.
authors.forename: W
authors.initials: W
authors.lastname: Zatonski
authors.forename: K
authors.initials: K
authors.lastname: Przewozniak
authors.forename: G R
authors.initials: GR
authors.lastname: Howe
authors.forename: P
authors.initials: P
authors.lastname: Maisonneuve
authors.forename: A M
authors.initials: AM
authors.lastname: Walker
authors.forename: P
authors.initials: P
authors.lastname: Boyle
mesh_terms: D016022:Case-Control Studies; D002791:Cholesterol, Dietary; D003710:Demography; D004032:Diet; D004041:Dietary Fats; D005260:Female; D006801:Humans; D007407:Interviews as Topic; D008019:Life Style; D008297:Male; D010190:Pancreatic Neoplasms / Q000453:epidemiology* / Q000209:etiology / Q000401:mortality; D011044:Poland; D012042:Registries; D014801:Vitamin A
chemical_list: D002791:Cholesterol, Dietary; D004041:Dietary Fats; D014801:Vitamin A