[Bronchoalveolar lavage--a diagnostic method in chronic nonspecific bronchopulmonary diseases in childhood? 2. Studies of cellular and humoral parameters in BAL irrigation fluid].
With a view of the pathogenesis of chronic bronchopulmonary diseases the interrelations between infections and evolving defense system are of interest, they are perhaps detectable by means of diagnostic bronchoalveolar lavage. We carried out cytodifferentiation, investigated adenosine deaminase activities and interleukin 1 formation of macrophages, determined immunoglobulin concentrations (secretory IgA), lysozyme, alpha 2-macroglobulin, alpha 1-antitrypsin, albumin. Because the cytodifferentiation yields insight into topical inflammatory reactions, shows diagnostic useful informations in single cases and because it is simple to carry out we can recommend it for each bronchological examination. There were no results specific for any disease group for parameters mentioned above.
Hein
J
J
Klinik für Kinderheilkunde, Universität Rostock.
Martens
E
E
Bauer
I
I
Dörfling
P
P
Brock
J
J
Gülzow
H U
HU
Breuel
K
K
Rudolph
I
I
D000243:Adenosine Deaminase / Q000032:analysis; D000293:Adolescent; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry / Q000166:cytology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007153:Immunologic Deficiency Syndromes / Q000175:diagnosis* / Q000276:immunology; D007223:Infant; D007375:Interleukin-1 / Q000032:analysis; D007958:Leukocyte Count; D008173:Lung Diseases, Obstructive / Q000175:diagnosis* / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D008297:Male; D009113:Muramidase / Q000032:analysis; D012141:Respiratory Tract Infections / Q000175:diagnosis* / Q000276:immunology; D012709:Serum Albumin / Q000032:analysis; D000515:alpha 1-Antitrypsin / Q000032:analysis
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007375:Interleukin-1; D012709:Serum Albumin; D000515:alpha 1-Antitrypsin; D009113:Muramidase; D000243:Adenosine Deaminase
Die bronchoalveoläre Lavage (BAL)--eine diagnostische Methode bei chronischen unspezifischen bronchopulmonalen Erkrankungen im Kindesalter? 2. Teil: Untersuchungen der zellulären und humoralen Parameter der BAL-Spülflüssigkeit.