title: CT-based optimized planning for transperineal prostate implant with customized template.
abstract: A computerized planning procedure has been developed for CT-guided transperineal prostate implants. The segment for custom planning of perineal needle orientations allows placement of I-125 seeds in the entire prostate gland while avoiding the pubic bones. Least-squares optimization (LSO) is used to obtain the seed-loading pattern along the needles. The optimized seed distribution produces a better fit between treatment and target volumes than that obtained from our previous manual technique. Also, the present semi-automatic technique reduces planning time by about a factor of 10 compared to that of the manual approach.
authors.affiliation: Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.
authors.forename: J N
authors.initials: JN
authors.lastname: Roy
authors.forename: K E
authors.initials: KE
authors.lastname: Wallner
authors.forename: S T
authors.initials: ST
authors.lastname: Chiu-Tsao
authors.forename: L L
authors.initials: LL
authors.lastname: Anderson
authors.forename: C C
authors.initials: CC
authors.lastname: Ling
mesh_terms: D001918:Brachytherapy / Q000295:instrumentation*; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D011880:Radiotherapy Planning, Computer-Assisted; D014057:Tomography, X-Ray Computed