Hypohydration does not impair skeletal muscle glycogen resynthesis after exercise.
The purpose of this investigation was to examine the effects of moderate hypohydration (HY) on skeletal muscle glycogen resynthesis after exhaustive exercise. On two occasions, eight males completed 2 h of intermittent cycle ergometer exercise (4 bouts of 17 min at 60% and 3 min at 80% of maximal O2 consumption/10 min rest) to reduce muscle glycogen concentrations (control values 711 +/- 41 mumol/g dry wt). During one trial, cycle exercise was followed by several hours of light upper body exercise in the heat without fluid replacement to induce HY (-5% body wt); in the second trial, sufficient water was ingested during the upper body exercise and heat exposure to maintain euhydration (EU). In both trials, 400 g of carbohydrate were ingested at the completion of exercise and followed by 15 h of rest while the desired hydration level was maintained. Muscle biopsy samples were obtained from the vastus lateralis immediately after intermittent cycle exercise (T1) and after 15 h of rest (T2). During the HY trial, the muscle water content was lower (P less than 0.05) at T1 and T2 (288 +/- 9 and 265 +/- 5 ml/100 g dry wt, respectively; NS) than during EU (313 +/- 8 and 301 +/- 4 ml/100 g dry wt, respectively; NS). Muscle glycogen concentration was not significantly different during EU and HY at T1 (200 +/- 35 vs. 251 +/- 50 mumol/g dry wt) or T2 (452 +/- 34 vs. 491 +/- 35 mumol/g dry wt). These data indicate that, despite reduced water content during the first 15 h after heavy exercise, skeletal muscle glycogen resynthesis is not impaired.
Neufer
P D
PD
US Army Research Institute of Environmental Medicine, Natick, Massachusetts 01760-5007.
Sawka
M N
MN
Young
A J
AJ
Quigley
M D
MD
Latzka
W A
WA
Levine
L
L
D000293:Adolescent; D000328:Adult; D001834:Body Water / Q000378:metabolism; D003681:Dehydration / Q000378:metabolism*; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D015444:Exercise / Q000502:physiology*; D006003:Glycogen / Q000096:biosynthesis*; D006801:Humans; D008297:Male; D009132:Muscles / Q000378:metabolism*; D010101:Oxygen Consumption; D013546:Sweating / Q000502:physiology
D004040:Dietary Carbohydrates; D006003:Glycogen