The activation of alcohols by liver alcohol dehydrogenase: dependence of inhibition upon the pKa lowering effect.
Pocker
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Department of Chemistry, University of Washington, Seattle 98195.
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JD
D000426:Alcohol Dehydrogenase / Q000037:antagonists & inhibitors / Q000378:metabolism*; D000438:Alcohols / Q000494:pharmacology*; D000818:Animals; D000431:Ethanol / Q000378:metabolism*; D006736:Horses; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D008433:Mathematics; D008962:Models, Theoretical; D010084:Oxidation-Reduction; D011485:Protein Binding; D013329:Structure-Activity Relationship
D000438:Alcohols; D000431:Ethanol; D000426:Alcohol Dehydrogenase