title: [Significance of hyponatremia in patients with oropharyngeal tumors].
abstract: We observed 29 patients with hyponatremia associated with oropharyngeal carcinoma. In 19/29 the hyponatremia was attributable to a decreased effective arterial blood volume whereas in the remainder (10/29) the presence of SIADH could be demonstrated. These etiologies of hyponatremia were best differentiated by the plasma urea concentration (less than 30 mg/dl in SIADH), urate concentration (less than 4,0 mg/dl in SIADH) and creatinine concentration (less than 0,9 mg/dl in SIADH). Furthermore, SIADH patients had a spontaneous natriuresis. The mainstay of therapy in either form of hyponatremia is fluid restriction (less than 1 l/d).
authors.affiliation: Medizinische Universitätsklinik, Heidelberg.
authors.forename: M
authors.initials: M
authors.lastname: Ketteler
authors.forename: P
authors.initials: P
authors.lastname: Gross
authors.forename: S
authors.initials: S
authors.lastname: Menstell
authors.forename: H
authors.initials: H
authors.lastname: Weidauer
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000503:physiopathology*; D003404:Creatinine / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000209:etiology / Q000503:physiopathology*; D007177:Inappropriate ADH Syndrome / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009959:Oropharyngeal Neoplasms / Q000503:physiopathology*; D012964:Sodium / Q000097:blood; D014882:Water-Electrolyte Balance / Q000502:physiology*
chemical_list: D012964:Sodium; D003404:Creatinine
vernacular_title: Bedeutung der Hyponatriämie bei Patienten mit oropharyngealen Tumoren.