title: Anticarbamazepine antibody induced by carbamazepine in a patient with severe serum sickness.
abstract: Anticarbamazepine antibody was detected in a patient who had clinical signs of serum sickness induced by carbamazepine. Skin rash, fever, oedema, and lymphadenopathy are classic signs of severe adverse reaction, but although immunological hypersensitivity is thought to be a contributory factor, the presence of anticarbamazepine antibody has not previously been reported to our knowledge.
authors.affiliation: Department of Paediatrics, Kitasato University School of Medicine, Kanagawa, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Hosoda
authors.forename: W
authors.initials: W
authors.lastname: Sunaoshi
authors.forename: H
authors.initials: H
authors.lastname: Shirai
authors.forename: Y
authors.initials: Y
authors.lastname: Bando
authors.forename: H
authors.initials: H
authors.lastname: Miura
authors.forename: M
authors.initials: M
authors.lastname: Igarashi
mesh_terms: D000818:Animals; D000917:Antibody Formation / Q000187:drug effects*; D002220:Carbamazepine / Q000009:adverse effects / Q000276:immunology*; D002648:Child; D004342:Drug Hypersensitivity; D005260:Female; D006801:Humans; D051379:Mice; D012713:Serum Sickness / Q000139:chemically induced / Q000276:immunology*
chemical_list: D002220:Carbamazepine