Superoxide dismutase activity regulation by spermine: a new dimension in spermine biochemistry and sperm development.
Amines are a group of highly important compounds of biological importance; they are known promoters of cell growth, can complex with nucleic acids and can stimulate DNA-primed RNA polymerase activity. Spermine, a polyamine abundantly present in the secretions of the male accessory sex organs, has received no functional attributes till date. This study had been a pioneer attempt to validate the hypothesis of a metalloenzyme activity modulation by spermine and implicit correlations have been drawn.
Singh
A
A
School of Life Sciences, Devi Ahilya Vishwavidyalaya, India.
Kumar
P
P
Laloraya
M
M
Verma
S
S
Nivsarkar
M
M
D000818:Animals; D006224:Cricetinae; D004822:Epididymis / Q000502:physiology; D066298:In Vitro Techniques; D008297:Male; D008647:Mesocricetus; D013075:Sperm Capacitation; D013094:Spermatozoa / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D013096:Spermine / Q000494:pharmacology*; D013482:Superoxide Dismutase / Q000378:metabolism*
D013096:Spermine; D013482:Superoxide Dismutase