title: Abortion and serological reaction of ewes after conjunctival instillation of Salmonella enterica subsp enterica ser abortusovis.
abstract: The aim of the experiment was to evaluate in pregnant ewes the clinical, bacteriological and serological effects of conjunctival instillation of S abortusovis. An individual dose of 1 x 10(10) viable S abortusovis were administered to 20 ewes 92 d after mating. Among 18 pregnant ewes, 8 aborted 110 +/- 13 d after mating, 4 had stillborn lambs and 6 a clinically normal lambing (114 +/- 1.3 d). S abortusovis was isolated from placentas, swabs and foetuses of the 12 lambings. Evolution of "H" agglutination titers measured by means of a microtechnique using a coloured antigen was found to be independent of the clinical results. Instillation by conjunctival route could constitute an experimental model closer to a natural mode of infection than the subcutaneous route.
authors.affiliation: CNEVA, Laboratoire de Pathologie, Biot, France.
authors.forename: R
authors.initials: R
authors.lastname: Sanchis
authors.forename: P
authors.initials: P
authors.lastname: Pardon
authors.forename: G
authors.initials: G
authors.lastname: Abadie
mesh_terms: D000034:Abortion, Veterinary / Q000276:immunology / Q000382:microbiology*; D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D003228:Conjunctiva; D005260:Female; D011247:Pregnancy; D012475:Salmonella / Q000145:classification / Q000276:immunology* / Q000472:pathogenicity; D012481:Salmonella Infections, Animal / Q000150:complications / Q000276:immunology*; D012756:Sheep; D012757:Sheep Diseases / Q000276:immunology / Q000382:microbiology*
chemical_list: D000907:Antibodies, Bacterial