title: [Status of immunologic reactivity in children and adolescents depending on the characteristics of the epidemiologic environment].
abstract: An immunologic examination of 118 children and adolescents was carried out, which showed a moderate inhibitions of T-cell functional activity and their proportion in persons who were contacting smear-negative tuberculosis patients and in those who had contacted before. However, a genuine drop in the cell population was not traced in the majority of them. More drastic changes occurred in T lymphocytes, including a decrease in both their relative and absolute numbers, are detected in the examinees contacting smear-positive tuberculosis patients, especially in the first year of their detection. By and large the intensity of specific cellular reactions reflects the degree of an epidemic hazard of the foci if there is a contact with active tuberculosis patients.
authors.forename: N L
authors.initials: NL
authors.lastname: Zagoruĭko
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007111:Immunity, Cellular; D012397:Rosette Formation; D013601:T-Lymphocytes / Q000276:immunology; D014376:Tuberculosis / Q000276:immunology*
vernacular_title: Sostoianie immunologicheskoĭ reaktivnosti u deteĭ i podrostkov v zavisimosti ot osobennosti épidemiologicheskogo okruzheniia.