title: [Primary intracerebral malignant lymphoma of the aged].
abstract: Primary intracerebral malignant lymphoma is non-Hodgkin's lymphoma originating in the central nervous system. It is a rare disease, comprising 1% of all brain tumors and 1.6% of extranodal non-Hodgkin's lymphoma, but its frequency has increased recently in aged patients. The ages of the 10 patients (8 men and 2 women) ranged from 31 to 79 years and average 56 years. In 5 patients over 60 years old (mean age 72), a solitary lesion was found in 2 patients and multiple lesions in 3 patients on a contrast-enhanced scan. One patients are still alive, but 4 died, after surviving 4 months on average. In 5 patients under 60 years old (average 39), single lesion were present in 4 and multiple in 1. Two patients are still alive three patients have died. Their median survival was 4 years and 11 months. In conclusion, primary intracerebral malignant lymphoma increased frequency in aged patients. Their tumors were generally larger and more often multiple, and their prognosis was definitely poor.
authors.affiliation: Department of Neurosurgery, Nagasaki University School of Medicine.
authors.forename: S
authors.initials: S
authors.lastname: Shibata
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001932:Brain Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011379:Prognosis