title: [Massive necrotizing adenitis complicating a disseminated herpes simplex virus 2 infection in chronic lymphoid leukemia].
abstract: We report a case of a 68 years old male patient treated for chronic lymphocytic leukaemia, presenting a right inguino-crural tender lymphadenopathy with periadenitis. The histologic changes associated with adenitis were large foci of necrosis with regular crown of epithelioid cells, without giant cell. The presence of Herpes simplex virus 2 was confirmed by immunohistochemistry and culture. Occurrence, physiopathology, clinical and histological aspects of Herpes simplex lymphadenitis in patients with haematologic disorders, are discussed.
authors.affiliation: Service d'anatomie pathologique, Hôpital d'Instruction des Armées Ste Anne, Toulon Naval.
authors.forename: C
authors.initials: C
authors.lastname: Pierre
authors.forename: D
authors.initials: D
authors.lastname: Jaubert
authors.forename: E
authors.initials: E
authors.lastname: Carloz
authors.forename: P
authors.initials: P
authors.lastname: Duval
authors.forename: A
authors.initials: A
authors.lastname: Boudon
mesh_terms: D000368:Aged; D000423:Alcian Blue; D046508:Culture Techniques; D005455:Fluorescent Antibody Technique; D006561:Herpes Simplex / Q000150:complications*; D006801:Humans; D007150:Immunohistochemistry; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications*; D008199:Lymphadenitis / Q000209:etiology* / Q000473:pathology; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D009336:Necrosis
chemical_list: D000423:Alcian Blue
vernacular_title: Adénite nécrosante massive compliquant une infection disséminée à herpes simplex virus 2, au cours d'une leucémie lymphoïde chronique.