title: [Leiomyosarcoma of the larynx. Histological, immunohistochemical and ultrastructural study of a case with review of the literature].
abstract: Laryngeal leiomyosarcoma: histological, immunohistochemical and ultrastructural study of one case with review of the literature. Leiomyosarcoma of the larynx have rarely been reported and a review of the literature has yielded only 8 cases. Authors report a case in a 45-year-old patient. Histological exam of the surgical specimen showed a malignant spindle cell tumor. Ultrastructurally, neoplastic cells presented some features of smooth-muscle cells. Immunohistochemical studies revealed that most tumor cells coexpressed vimentin and smooth-muscle actin.
authors.affiliation: Laboratoire d'anatomie et cytologie pathologiques, Hôpital Saint-Louis, Paris.
authors.forename: P
authors.initials: P
authors.lastname: Bertheau
authors.forename: A
authors.initials: A
authors.lastname: Deboise
authors.forename: A
authors.initials: A
authors.lastname: De Roquancourt
authors.forename: C
authors.initials: C
authors.lastname: Brocheriou
mesh_terms: D000199:Actins / Q000032:analysis; D014408:Biomarkers, Tumor; D006801:Humans; D007124:Immunoenzyme Techniques; D007822:Laryngeal Neoplasms / Q000737:chemistry* / Q000473:pathology* / Q000648:ultrastructure; D007890:Leiomyosarcoma / Q000737:chemistry* / Q000473:pathology* / Q000648:ultrastructure; D008297:Male; D008875:Middle Aged; D014746:Vimentin / Q000032:analysis
chemical_list: D000199:Actins; D014408:Biomarkers, Tumor; D014746:Vimentin
vernacular_title: Léiomyosarcome du larynx. Etude histologique, immunohistochimique et ultrastructurale d'une observation avec revue de la littérature.