title: cDNA sequence of Xenopus laevis bone morphogenetic protein 2 (BMP-2).
abstract: Screening of a Xenopus laevis ovary cDNA library with an oligonucleotide derived from the activin A sequence led to the isolation of several clones belonging to the TGF-beta supergene family. One of these clones codes for the Xenopus bone morphogenetic protein 2 (BMP-2). The deduced protein contains 398 amino acids with a predicted Mr of 45,581. Within the C-terminal 114 amino acids constituting the mature, biologically active protein there are only four exchanges (three of them are conservative ones) as compared to the corresponding human sequence.
authors.affiliation: Department of Biochemistry, University of Ulm, F.R.G.
authors.forename: S
authors.initials: S
authors.lastname: Plessow
authors.forename: M
authors.initials: M
authors.lastname: Köster
authors.forename: W
authors.initials: W
authors.lastname: Knöchel
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D019485:Bone Morphogenetic Proteins; D004247:DNA / Q000235:genetics*; D006133:Growth Substances / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D011506:Proteins / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D014982:Xenopus laevis
chemical_list: D019485:Bone Morphogenetic Proteins; D006133:Growth Substances; D011506:Proteins; D004247:DNA