title: Availability of fluoride from glass-ionomer luting cements in human saliva.
abstract: Fluoride availability from two glass-ionomer luting agents, Ketac-Cement and Aqua-Cement, was monitored after a 1-h treatment in distilled water at pH 7. The recorded results were then compared to the ones obtained from those same cements, after 1 h, in saliva, in water pretreated with saliva (pH 7 and 4.5), and in albumen and phosphate buffer solutions (pH 7). The Mann-Whitney two-sample rank test was utilized in order to identify the differences. The presence of proteins and phosphate reduced fluoride availability. A reduction in the pH from 7 to 4.5 resulted in an increased rate of fluoride release, in water, from glass-ionomers pretreated with saliva. The present study indicates that fluoride availability from glass-ionomers, in vivo, is pH controlled. The rate controlling factors appear to be phosphate and proteins.
authors.affiliation: Department of Orthodontics, University of Oslo, Norway.
authors.forename: F
authors.initials: F
authors.lastname: Rezk-Lega
authors.forename: B
authors.initials: B
authors.lastname: Ogaard
authors.forename: G
authors.initials: G
authors.lastname: Rölla
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry; D000418:Albumins / Q000737:chemistry; D002021:Buffers; D004058:Diffusion; D005459:Fluorides / Q000032:analysis / Q000737:chemistry*; D005899:Glass Ionomer Cements / Q000737:chemistry*; D006801:Humans; D008277:Magnesium Oxide / Q000737:chemistry; D010710:Phosphates / Q000737:chemistry; D011076:Polycarboxylate Cement / Q000737:chemistry; D012463:Saliva / Q000737:chemistry*; D014867:Water / Q000737:chemistry; D015034:Zinc Oxide / Q000737:chemistry
chemical_list: D000180:Acrylic Resins; D000418:Albumins; D002021:Buffers; D005899:Glass Ionomer Cements; D010710:Phosphates; D011076:Polycarboxylate Cement; D014867:Water; C045751:Aqua-cem; D008277:Magnesium Oxide; C040235:Ketac-cem; D005459:Fluorides; D015034:Zinc Oxide