title: Thoracic lymph drainage in the dog: evaluation of a new model.
abstract: A new model for selective sampling of thoracic lymph flow (TLF) and abdominal lymph flow (TDA) in the dog was assessed to ascertain whether there were extrathoracic contributions of lymph to the TLF. Inflating a right atrial balloon in 4 dogs and a left atrial balloon in 2 dogs indicated good separation between TLF and TDA. Data on total lymph protein and albumin clearance before and after oleic acid induced pulmonary oedema in an additional 5 dogs indicated that TLF and TDA drained two differing regions. Our data demonstrate that this lymph preparation provides a sample of thoracic lymph flow with no major extrathoracic lymph contamination. We also propose an alternative method to test for extrathoracic contributions to thoracic lymph, by the application of positive end-expiratory pressure, thereby replacing right atrial balloon inflation.
authors.affiliation: Department of Anaesthesia and Intensive Care, Danderyd Hospital, Sweden.
authors.forename: H
authors.initials: H
authors.lastname: Blomqvist
authors.forename: B
authors.initials: B
authors.lastname: Berg
authors.forename: C
authors.initials: C
authors.lastname: Frostell
authors.forename: C J
authors.initials: CJ
authors.lastname: Wickerts
authors.forename: G
authors.initials: G
authors.lastname: Hedenstierna
mesh_terms: D000418:Albumins / Q000032:analysis; D000818:Animals; D001798:Blood Proteins / Q000032:analysis; D002404:Catheterization; D004195:Disease Models, Animal; D004285:Dogs; D006325:Heart Atria; D006439:Hemodynamics; D008168:Lung / Q000502:physiology*; D008196:Lymph / Q000737:chemistry; D008208:Lymphatic System / Q000502:physiology*; D011175:Positive-Pressure Respiration; D011506:Proteins / Q000032:analysis; D011652:Pulmonary Circulation / Q000502:physiology*; D012121:Respiration, Artificial; D012212:Rheology; D012709:Serum Albumin / Q000032:analysis
chemical_list: D000418:Albumins; D001798:Blood Proteins; D011506:Proteins; D012709:Serum Albumin