Steroid therapy and duodenal ulcer in infants.
Two infants with acute life-threatening complications of duodenal ulcer following steroid administration are described. Although the possible association between steroid therapy and peptic ulcer disease is well known, the need for ulcer prophylaxis during such therapy in infants is not unanimously accepted. The case for ulcer prophylaxis in this setting is presented.
Wolf
Y G
YG
Department of Pediatric Surgery, Children's Hospital, Columbus, Ohio.
Reyna
T
T
Schropp
K P
KP
Harmel
R P
RP
D001997:Bronchopulmonary Dysplasia / Q000188:drug therapy; D003907:Dexamethasone / Q000009:adverse effects*; D004381:Duodenal Ulcer / Q000139:chemically induced* / Q000150:complications; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010438:Peptic Ulcer Hemorrhage / Q000209:etiology; D010439:Peptic Ulcer Perforation / Q000209:etiology
D003907:Dexamethasone