title: [Autoimmune hemolytic anemia associated with severe giant cell hepatitis].
abstract: Autoimmune hemolytic anemia and severe giant cell hepatitis is an very uncommon association. Two patients aged 5 months and 2 years developed severe anemia, jaundice, hepatomegaly and splenomegaly. Laboratory tests demonstrated autoimmune hemolytic anemia and elevated amino-transferases. Diffuse giant cell transformation and distorted architecture was seen in liver biopsy. One patient had a cytomegalovirus infection. Early steroid therapy did not prevent fatal course with liver failure in one patient.
authors.affiliation: Servicio de Pediatría, Hospital Ramón y Cajal, Madrid.
authors.forename: C
authors.initials: C
authors.lastname: Camarero Salcés
authors.forename: F
authors.initials: F
authors.lastname: Vasconez Muñoz
authors.forename: D
authors.initials: D
authors.lastname: San José Hernando
authors.forename: P
authors.initials: P
authors.lastname: Morales
authors.forename: L
authors.initials: L
authors.lastname: Suárez Cortina
authors.forename: C
authors.initials: C
authors.lastname: Parra Vázquez
authors.forename: H
authors.initials: H
authors.lastname: Escobar Castro
authors.forename: A
authors.initials: A
authors.lastname: Muñoz Villa
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications* / Q000276:immunology; D006505:Hepatitis / Q000150:complications* / Q000276:immunology; D006801:Humans; D007223:Infant; D008297:Male
vernacular_title: Anemia hemolítica autoinmune y hepatitis severa con transformación giganto celular.