title: Mitral valve replacement in idiopathic hypereosinophilic syndrome.
abstract: Idiopathic hypereosinophilic syndrome is an eosinophil-mediated tissue injury causing multiple organ failure. Cardiac manifestations include subendocardial fibrosis, thrombus leading to peripheral emboli, restrictive cardiomyopathy, and valvar dysfunction. This article describes a patient with the syndrome and reviews surgical experience with valve replacement and long-term prognosis.
authors.affiliation: Department of Surgery, University of Rochester Medical Center, New York.
authors.forename: C W
authors.initials: CW
authors.lastname: Boustany
authors.forename: G W
authors.initials: GW
authors.lastname: Murphy
authors.forename: G L
authors.initials: GL
authors.lastname: Hicks
mesh_terms: D000328:Adult; D004802:Eosinophilia / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006333:Heart Failure / Q000209:etiology; D006350:Heart Valve Prosthesis; D006801:Humans; D008943:Mitral Valve / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000209:etiology / Q000601:surgery; D008946:Mitral Valve Stenosis / Q000209:etiology / Q000601:surgery; D013577:Syndrome; D013927:Thrombosis / Q000209:etiology