[Immunomodulating effect of levamisole in antibiotic therapy].
The use of ampicillin, benzylpenicillin, gentamicin, erythromycin, cefamezine or cephaloridine in combination with levamisole aimed at increasing their efficacy and correcting the adverse reactions was studied. Immunological activity of the antibiotics was comparatively characterized by using standard methods. It was shown that the character of the antibiotic effect on the basic factors of nonspecific resistance and immunity was heterogeneous. Schemes for using the antibiotics in combination with levamisole for correcting the detected disorders in the immunity status of the experimental animals were developed.
Kynina
E S
ES
Dziubak
S T
ST
Vitvitskiĭ
V M
VM
Nikitin
A V
AV
Nikiforchin
R N
RN
Smolinskaia
L E
LE
Lysenko
Iu G
IuG
D000276:Adjuvants, Immunologic; D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D004195:Disease Models, Animal; D004359:Drug Therapy, Combination; D007108:Immune Tolerance / Q000187:drug effects / Q000276:immunology; D007978:Levamisole / Q000008:administration & dosage*; D051379:Mice; D009894:Opportunistic Infections / Q000188:drug therapy* / Q000209:etiology / Q000276:immunology; D011817:Rabbits; D051381:Rats; D012481:Salmonella Infections, Animal / Q000188:drug therapy* / Q000209:etiology / Q000276:immunology; D012486:Salmonella typhimurium / Q000187:drug effects / Q000472:pathogenicity*
D000276:Adjuvants, Immunologic; D000900:Anti-Bacterial Agents; D007978:Levamisole
Immunomoduliruiushchee vliianie levamizola v usloviiakh antibiotikoterapii.