title: S-100 immunoreactive cells in the spleen and bursa of Fabricius of broiler chickens.
abstract: The distribution of S-100 protein in spleens and bursae of Fabricius of broiler chickens with various diseases was investigated by an immunohistochemical method with antiserum to bovine S-100 protein. S-100 protein-positive cells were found in six cases of 34 chickens. In spleens, S-100 protein was detected in reticular cells in the ellipsoids of the sheathed arteries and eosinophilic granulocytes. Follicular dendritic cells in germinal centres were also S-100 protein-positive. In the bursa, reticular cells of the follicles and eosinophilic granulocytes in the follicular cortex and surface epithelium were positive for S-100 protein. The evidence suggests that S-100 protein may be involved in diseases of chickens.
authors.affiliation: Department of Veterinary Anatomy, Faculty of Agriculture, Gifu University, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Atoji
authors.forename: A
authors.initials: A
authors.lastname: Kato
authors.forename: T
authors.initials: T
authors.lastname: Masegi
authors.forename: T
authors.initials: T
authors.lastname: Nakaoka
authors.forename: Y
authors.initials: Y
authors.lastname: Suzuki
mesh_terms: D000818:Animals; D002060:Bursa of Fabricius / Q000737:chemistry / Q000473:pathology*; D002645:Chickens / Q000033:anatomy & histology* / Q000378:metabolism; D005260:Female; D007124:Immunoenzyme Techniques; D008297:Male; D011201:Poultry Diseases / Q000378:metabolism / Q000473:pathology*; D009418:S100 Proteins / Q000032:analysis*; D013154:Spleen / Q000737:chemistry / Q000473:pathology*
chemical_list: D009418:S100 Proteins