Intraocular tumor from disseminated histoplasmosis.
We identified and treated a solid, growing fungal tumor mass in a patient with disseminated histoplasmosis. Although the most commonly reported intraocular lesions from disseminated histoplasmosis are areas of inactive chorioretinal scars or areas of localized subretinal neovascular membrane formation, a focus of active fungal growth needs to be ruled out in all such cases. When a solid tumor mass is identified, the most effective way of preserving vision is with systemic antifungal therapy.
Feman
S S
SS
Department of Ophthalmology, School of Medicine, Vanderbilt University, Nashville, TN 37232-2540.
Pritchett
P
P
Johns
K
K
Westrich
D J
DJ
Salmon
W D
WD
D000666:Amphotericin B / Q000627:therapeutic use; D005134:Eye Neoplasms / Q000188:drug therapy / Q000209:etiology*; D006660:Histoplasmosis / Q000150:complications*; D006801:Humans; D007654:Ketoconazole / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D014792:Visual Acuity / Q000187:drug effects
D000666:Amphotericin B; D007654:Ketoconazole