[Amoebic keratitis caused by Acanthamoeba sp. May HSV1 infection play a role?].
Many cases of human keratitis with Acanthamoeba sp. have a pseudo-herpetic appearance. The authors therefore evaluated the importance of co-infection with this virus in the onset of amoebic cornean lesions. After herpetic and amoebic co-infection rabbits showed severe cornean lesions, the viral aspect of cornea received a specific treatment. The amoebic co-infection progressed unchecked with severe lesions until day 37 p.i., in which trophozoites and cysts were numerous. The possible favourising role of HSV1 and Acanthamoeba sp. co-infection may exist in humans, just as it certainly exists in the rabbit.
Paniagua-Crespo
E
E
Laboratoire de Parasitologie, UFR de Médecine, Brest.
Tsouria-Belaid
A
A
Bellon
C
C
Jacquemin
J L
JL
Simitzis-Le Flohic
A M
AM
D015823:Acanthamoeba Keratitis / Q000150:complications* / Q000175:diagnosis; D000818:Animals; D003315:Cornea / Q000473:pathology*; D003937:Diagnosis, Differential; D004195:Disease Models, Animal; D006561:Herpes Simplex / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D007165:Immunosuppression Therapy; D011817:Rabbits; D013997:Time Factors
Kératite amibienne à Acanthamoeba sp. L'infection par HSV1 aurait-elle un rôle?