title: Intense immunoreactivity for Mn-superoxide dismutase (Mn-SOD) in cholinergic and non-cholinergic neurons in the rat basal forebrain.
abstract: The immunohistochemical localization of manganese (Mn)-superoxide dismutase (Mn-SOD) was studied in the rat basal forebrain using polyclonal antibodies to Mn-SOD. Neurons of the basal forebrain exhibit a high density of Mn-SOD immunoreactivity. Double immunostaining with a monoclonal antibody to choline acetyltransferase demonstrated that both cholinergic and non-cholinergic neurons in the basal forebrain are intensely immunoreactive for Mn-SOD.
authors.affiliation: Department of Anatomy, Osaka City University Medical School, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Inagaki
authors.forename: H
authors.initials: H
authors.lastname: Takagi
authors.forename: K
authors.initials: K
authors.lastname: Suzuki
authors.forename: F
authors.initials: F
authors.lastname: Akai
authors.forename: N
authors.initials: N
authors.lastname: Taniguchi
mesh_terms: D000818:Animals; D002795:Choline O-Acetyltransferase / Q000276:immunology; D004591:Electrophoresis, Polyacrylamide Gel; D005455:Fluorescent Antibody Technique; D015151:Immunoblotting; D007150:Immunohistochemistry; D008297:Male; D009474:Neurons / Q000201:enzymology* / Q000276:immunology; D010275:Parasympathetic Nervous System / Q000201:enzymology* / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains; D013482:Superoxide Dismutase / Q000276:immunology*
chemical_list: D013482:Superoxide Dismutase; D002795:Choline O-Acetyltransferase