[Contribution to the study of NORs in acinic cell tumors of the salivary glands. Morphometric comparative analysis by optic and electronic microscopy].
Quantification of number and mean area of NORs was retrospectively studied in six acinic cell tumors with a well-known follow-up by means of electron microscopy without any silver staining. The results were compared with those obtained using silver staining and optical quantification. Mean areas were inversely correlated with the number of NORs. Positive correlations were found between these results and the clinical course: tumors with good outcome were characterized by a low NOR count (less than 2) and by large mean areas (greater than 600 microns 2); on the contrary, tumors with recurrences or metastases always had high NOR counts with small mean areas.
Chomette
G
G
Service Central d'Anatomie Pathologique, Groupe Hospitalier Pitié-Salpêtrière, Paris.
Auriol
M
M
D002277:Carcinoma / Q000473:pathology / Q000648:ultrastructure*; D005500:Follow-Up Studies; D006801:Humans; D008853:Microscopy; D008854:Microscopy, Electron; D009697:Nucleolus Organizer Region / Q000648:ultrastructure*; D012468:Salivary Gland Neoplasms / Q000648:ultrastructure*
Contribution à l'étude des NORs dans les tumeurs à cellules acineuses des glandes salivaires. Analyse morphométrique comparative en microscopie optique et électronique.