Lens epithelial cells adhere less to HEMA than to PMMA intraocular lenses.
Following cataract surgery proliferation of residual lens epithelial cells may occur causing secondary opacification and loss of visual acuity. Using an in vitro system the abilities of bovine and porcine lens epithelial cells to adhere to two types of intraocular lens have been assessed. Lens epithelial cells adhere significantly less to lenses composed of poly 2 hydroxyethylmethacrylate (HEMA) than to polymethylmethacrylate (PMMA).
Humphry
R C
RC
West of England Eye Infirmary, Exeter.
Ball
S P
SP
Brammall
J E
JE
Conn
S J
SJ
Rich
W J
WJ
D000818:Animals; D002417:Cattle; D002448:Cell Adhesion; D002478:Cells, Cultured; D004847:Epithelial Cells; D007908:Lens, Crystalline / Q000166:cytology*; D007910:Lenses, Intraocular; D008689:Methacrylates; D008768:Methylmethacrylates; D011183:Postoperative Complications / Q000517:prevention & control; D013552:Swine
D008689:Methacrylates; D008768:Methylmethacrylates; C005044:hydroxyethyl methacrylate