title: Induction of autoantibodies by human immunodeficiency virus infection and their significance.
abstract: Although many of the changes in HIV and AIDS appear to be global, on closer investigation the defects are specific and can be explained by recognized mechanisms. Despite a demonstrated concurrent polyclonal B-cell activation, studies fail to show any evidence to date of significant dysregulation of the immune system leading to serologic or clinical autoimmunity.
authors.affiliation: Department of Internal Medicine, University of Cincinnati Medical Sciences Center, Ohio.
authors.forename: A M
authors.initials: AM
authors.lastname: Solinger
authors.forename: E V
authors.initials: EV
authors.lastname: Hess
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology; D001323:Autoantibodies / Q000032:analysis*; D006678:HIV / Q000276:immunology*; D015483:HIV Antibodies / Q000032:analysis*; D006679:HIV Seropositivity / Q000276:immunology; D006801:Humans; D008213:Lymphocyte Activation / Q000276:immunology
chemical_list: D001323:Autoantibodies; D015483:HIV Antibodies