title: Ras-related genes in Dictyostelium discoideum.
abstract: Dictyostelium discoideum, like other eukaryotes, has been shown to express several ras-related genes. Two gene products, Ddras and DdrasG, are highly conserved relative to the human ras proteins. Ddras is expressed at the pseudoplasmodial stage of development, whereas DdrasG is expressed in vegetative cells and during early development. In addition, Dictyostelium possesses three ras-related genes, SAS1, SAS2 and Ddrap1, whose gene products are only partially conserved relative to those of the ras genes. The expression of these three genes is also developmentally regulated.
authors.affiliation: Department of Microbiology, University of British Columbia, Vancouver, Canada.
authors.forename: S M
authors.initials: SM
authors.lastname: Robbins
authors.forename: M
authors.initials: M
authors.lastname: Khosla
authors.forename: R
authors.initials: R
authors.lastname: Thiery
authors.forename: G
authors.initials: G
authors.lastname: Weeks
authors.forename: G B
authors.initials: GB
authors.lastname: Spiegelman
mesh_terms: D000595:Amino Acid Sequence; D004023:Dictyostelium / Q000235:genetics* / Q000254:growth & development; D005656:Fungal Proteins / Q000096:biosynthesis / Q000235:genetics*; D015966:Gene Expression Regulation, Fungal; D005800:Genes, Fungal; D011905:Genes, ras; D006801:Humans; D008969:Molecular Sequence Data; D005810:Multigene Family; D012689:Sequence Homology, Nucleic Acid; D018631:ras Proteins
chemical_list: D005656:Fungal Proteins; C489016:ras protein, Dictyostelium; D018631:ras Proteins