[Preparation of thrombocyte concentrates in the Travenol CS-3000 separator (factors affecting the thrombocyte yield and presence of leukocytes)].
The authors made 184 thrombocytaphereses for the preparation of thrombocyte concentrates on a Travenol CS-3000 separator. They evaluate indicators on which the thrombocyte yield depends: it was found that the yield is higher in donors with a higher number of platelets and that it increases with the period of separation. The mean thrombocyte yield was 2.91 +/- 0.84 x 10(11). It corresponded to the average lower platelet number of donors--182 x 10(9)/L. In those donors where the number of platelets was higher than 180 x 10(9)/L, the yield was 3.21 x 10(9)/L. The undesirable presence of leucocytes (in 98% lymphocytes) increases in relation to the number of leucocytes in the donor and their decline after separation. It was lower in longer separations. The authors discuss the possibility to increase the thrombocyte yield without contamination with leucocytes.
Bláha
M
M
Vojenská lékarská akademie J. E. Purkynĕ, Hradec Králové.
Varvarovský
I
I
Pecka
M
M
Malý
J
J
Jebavý
L
L
Siroký
O
O
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D010983:Plateletpheresis / Q000295:instrumentation
Príprava trombocytárních koncentrátů separátorem Travenol CS-3000 (faktory mající vliv na výtĕzek trombocytů a prímĕs leukocytů).