title: Sister-chromatid exchanges (SCE) induced by p-dichlorobenzene in cultured human lymphocytes.
abstract: We have investigated the ability of p-dichlorobenzene (p-DCB) to induce sister-chromatid exchanges (SCE) in cultured human lymphocytes. From our results we can conclude that p-DCB was able to induce a cytotoxic effect, measured as a decrease in third and second metaphases, together with an increase of SCEs.
authors.affiliation: Departament de Genètica i de Microbiologia, Universitat Autònoma de Barcelona, Bellaterra, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Carbonell
authors.forename: M
authors.initials: M
authors.lastname: Puig
authors.forename: N
authors.initials: N
authors.lastname: Xamena
authors.forename: A
authors.initials: A
authors.lastname: Creus
authors.forename: R
authors.initials: R
authors.lastname: Marcos
mesh_terms: D002453:Cell Cycle / Q000187:drug effects; D002478:Cells, Cultured; D002722:Chlorobenzenes / Q000633:toxicity*; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects*; D009153:Mutagens; D012854:Sister Chromatid Exchange / Q000187:drug effects*
chemical_list: D002722:Chlorobenzenes; D009153:Mutagens; C018511:4-dichlorobenzene