Degradation of sucrase-isomaltase in the ileum of jejunum-bypassed rats.
At 3 weeks after jejunal-bypass operation in the rat, the proximal ileum exhibited a greater sucrase specific activity than did sham-operated controls, whereas isomaltase activity was unaffected. Electroimmunoassay of sucrase-isomaltase and a degradation product, isomaltase monomer, revealed an elevated molar ratio of sucrase subunit to isomaltase subunit in operated rats, suggesting a decrease in the extent of degradation of ileal sucrase-isomaltase after the jejunal-bypass operation.
Shinohara
H
H
Department of Education, Miyazaki University, Japan.
Goda
T
T
Takase
S
S
D000714:Anastomosis, Surgical; D000818:Animals; D007082:Ileum / Q000502:physiology* / Q000601:surgery; D007413:Intestinal Mucosa / Q000201:enzymology*; D007583:Jejunum / Q000502:physiology* / Q000601:surgery; D007700:Kinetics; D008297:Male; D009928:Organ Specificity; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values; D013394:Sucrase-Isomaltase Complex / Q000378:metabolism*
D013394:Sucrase-Isomaltase Complex