title: Investigation and diagnosis of hypertrophic pyloric stenosis.
abstract: Forty-nine infants who underwent investigation or surgery for hypertrophic pyloric stenosis (HPS) over a 30-month period were reviewed. Significant weight loss was present in 18 infants, of whom 16 had HPS. A test feed was performed in 46 infants with 1 of 27 false positive and 6 of 29 false negatives. An ultrasound examination was performed in 34 infants with 4 of 23 false positives and 1 of 11 false negatives. It is recommended that if the test feed is positive then surgery should be performed, otherwise an ultrasound examination can be used as a screening test but a positive result should be confirmed by other means before surgery.
authors.affiliation: Department of Surgery, Frimley Park Hospital, UK.
authors.forename: S P
authors.initials: SP
authors.lastname: Huddy
mesh_terms: D005188:False Negative Reactions; D005189:False Positive Reactions; D006801:Humans; D006984:Hypertrophy / Q000473:pathology; D007231:Infant, Newborn; D008297:Male; D011707:Pyloric Stenosis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014463:Ultrasonography; D015431:Weight Loss