[Results of trans-sphenoidal surgery for the treatment of acromegaly].
During the past 17 years (1972-89) 55 transsphenoidal surgery (TSS) interventions were performed in our Hospital in 53 cases of acromagaly (2 cases underwent surgery twice).


RESULTS
22 were cured (40%); 15 partial efficacy (27%) and 18 negative efficacy (33%). Mean GH values (ngr/ml) before surgery were: Cured cases 15.8 + 12.9 (p = 0.0015). Basal GH values above 40 ngr/ml obscure the prognosis of TSS in acromegaly. Cure was perfectly achieved in smaller size hypophysis adenomas (Hardy Grade land 11 in CT scan). The complications in the early post-surgery were rare and transient. Chronic sequelae due to TSS occurred in 7 cases (13.5%), as complete or partial anterior hypophysis failure. TSS is the treatment of choice of acromegaly in our environment, however a significant number of cases do not achieve cure and need to complete treatment with hypophyseal radiotherapy.
Pumar
A
A
Servicio de Endocrinología, Hospital Virgen del Rocío, Sevilla.
Santos
C
C
García-Luna
P P
PP
Acosta
D
D
Pereira
J L
JL
Gavilán
I
I
Leal-Cerro
A
A
Astorga
R
R
D000172:Acromegaly / Q000097:blood / Q000209:etiology / Q000601:surgery*; D000236:Adenoma / Q000150:complications / Q000601:surgery*; D013006:Growth Hormone / Q000097:blood*; D006801:Humans; D010911:Pituitary Neoplasms / Q000150:complications / Q000601:surgery*; D011183:Postoperative Complications; D012074:Remission Induction; D013100:Sphenoid Bone
D013006:Growth Hormone
Resultados de la cirugía transesfenoidal en el tratamiento de la acromegalia.