title: [Clinical and experimental study on treatment of anorexy in children with the activating spleen prescription].
abstract: The treatment of 488 cases with anorexy in children showed that the curative effect of the group using Chinese medicines based on the differentiation of symptoms and signs by (1) activating the Spleen, (2) invigorating and activating the spleen was significantly higher than the control using concentrated vitamin B complex (P less than 0.001). The results of the experimental study were as follows: Erbao instant granules (the medicine for activating the Spleen) had the effect of raising the D-xylose excretion rate of urine; increasing the ratio of T-lymph cells in blood; raising the quality of 8 mineral elements in hair and the quality of SIgA in saliva; adjusting the abnormal peristalsis of the experimental rabbits and promoting the ability that duodenums which had been separated from rabbits had to absorb different amino acids and glucose. Jian'er syrup (the medicine for invigorating and activating the Spleen) had the effect of raising the quality of 14 mineral elements in hair; increasing the ratio of T-lymph cells in blood; increasing the index of thymus and spleen in the experimental rats and stimulating them to produce hemolysin. The authors tend to think that the therapeutic principle of activating the Spleen can improve appetite, help the body to absorb and utilize various nutrients which contain many kinds of essential trace elements.
authors.affiliation: Nanjing College of TCM.
authors.forename: S C
authors.initials: SC
authors.lastname: Wang
authors.forename: R D
authors.initials: RD
authors.lastname: You
mesh_terms: D000818:Animals; D000855:Anorexia / Q000188:drug therapy* / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D004365:Drugs, Chinese Herbal / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006197:Hair / Q000378:metabolism; D006801:Humans; D007223:Infant; D007408:Intestinal Absorption / Q000187:drug effects; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D011817:Rabbits; D014131:Trace Elements / Q000378:metabolism
chemical_list: D004365:Drugs, Chinese Herbal; C521474:Jian-er; D014131:Trace Elements