title: KBSIM/FLUIDTHERAPY: a system for optimized design of fluid resuscitation in trauma.
abstract: An application of the KBSIM (Knowledge-Based SIMulation) system to the improved design of fluid resuscitation is described. The system integrates knowledge from three domains, viz. the pathophysiology of traumatized patients represented in a quantitative biodynamic model, the heuristics of fluid resuscitation of such patients as represented in 'production rules', and some 'metaknowledge' reflected in the design of a multi-window user interface. This technique of combining numerical simulation with symbolic reasoning has obvious advantages during the design process and in training, by giving the user a possibility to evaluate his measures by direct feedback from the system. This feature of the system to assist in evaluation of alternative resuscitation procedures should also be useful as a means for decision support.
authors.affiliation: Unit for Biomedical Systems Analysis, Uppsala University, Sweden.
authors.forename: T
authors.initials: T
authors.lastname: Groth
authors.forename: M
authors.initials: M
authors.lastname: Hakman
authors.forename: A
authors.initials: A
authors.lastname: Hedlund
authors.forename: B
authors.initials: B
authors.lastname: Zaar
mesh_terms: D001185:Artificial Intelligence; D003198:Computer Simulation; D003199:Computer Systems; D003628:Database Management Systems; D003658:Decision Making, Computer-Assisted; D005440:Fluid Therapy; D006801:Humans; D008954:Models, Biological; D012151:Resuscitation; D012774:Shock, Traumatic / Q000517:prevention & control; D014584:User-Computer Interface