title: Vulnerability to sodium lactate in panic disorder patients given cognitive-behavioral therapy.
abstract: Six patients with panic disorder who had panicked during sodium lactate infusion were given cognitive-behavioral treatment for 12-24 weeks. After treatment they underwent another lactate infusion, and four patients were rates as having no panic, suggesting that reduced vulnerability to lactate accompanies remission of panic. Controlled trials of cognitive-behavioral therapy and use of lactate infusion as a measure of remission are recommended.
authors.affiliation: Department of Psychiatry, New York Hospital-Cornell University Medical College, NY 10021.
authors.forename: M K
authors.initials: MK
authors.lastname: Shear
authors.forename: A J
authors.initials: AJ
authors.lastname: Fyer
authors.forename: G
authors.initials: G
authors.lastname: Ball
authors.forename: S
authors.initials: S
authors.lastname: Josephson
authors.forename: M
authors.initials: M
authors.lastname: Fitzpatrick
authors.forename: B
authors.initials: B
authors.lastname: Gitlin
authors.forename: A
authors.initials: A
authors.lastname: Frances
authors.forename: J
authors.initials: J
authors.lastname: Gorman
authors.forename: M
authors.initials: M
authors.lastname: Liebowitz
authors.forename: D F
authors.initials: DF
authors.lastname: Klein
mesh_terms: D000293:Adolescent; D000328:Adult; D001008:Anxiety Disorders / Q000139:chemically induced* / Q000523:psychology / Q000628:therapy; D015928:Cognitive Behavioral Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007262:Infusions, Intravenous; D007773:Lactates / Q000008:administration & dosage; D019344:Lactic Acid; D008297:Male; D010200:Panic; D010865:Pilot Projects; D011569:Psychiatric Status Rating Scales
chemical_list: D007773:Lactates; D019344:Lactic Acid