[Experimental peritoneal calcinosis--glucocorticoid as inhibitor].
Peritoneal disturbances in the course of continuous ambulatory peritoneal dialysis (CAPD) are therapeutical relevant. Even calcifications are described in rarely cases. Concerning these cases an experimental model is known being created by Selye and belonging to the calciphylactic concept. In 8 female Wistar rats (weighing 140 to 180 g) this experiment was reproduced and in a similar series an inhibition was achieved by intraperitoneal application of a glucocorticoid. Experiments in this kind give a pathogenetic contribution for peritoneal disturbances and also possible therapeutic hints.
Klemm
G
G
Klinik für Innere Medizin, Universität Rostock.
D000818:Animals; D002114:Calcinosis / Q000473:pathology / Q000517:prevention & control*; D004195:Disease Models, Animal; D005260:Female; D007274:Injections, Intraperitoneal; D010531:Peritoneal Dialysis, Continuous Ambulatory; D010532:Peritoneal Diseases / Q000473:pathology / Q000517:prevention & control*; D010537:Peritoneum / Q000473:pathology; D011239:Prednisolone / Q000008:administration & dosage / Q000031:analogs & derivatives*; D051381:Rats; D011919:Rats, Inbred Strains
D011239:Prednisolone; C021322:prednisolone hemisuccinate
Peritonealverkalkung im Experiment--Glucocorticoid als Inhibitor.