Reproducibility of glucose and insulin responses to mixed meal in type II diabetic patients.
OBJECTIVE
The reproducibility of glucose and insulin responses to a mixed meal were studied in 24 consecutive non-insulin-dependent (type II) diabetic patients, the diet of which matched the tested diet. Patients received their usual treatment throughout the study.


METHODS
A standardized diet was followed for 3 days, and responses were measured on the 2nd and 3rd days. Glucose and insulin responses were studied after lunches with the 180-min positive area under the curve, and were analyzed with paired t test and Pearson's linear regression.


RESULTS
Glucose responses did not vary (217 +/- 50 vs. 217 +/- 38 min x mM, NS) and were significantly correlated (r = 0.64, P less than 0.01). Insulin responses did not vary (35,224 +/- 5768 vs. 35,305 +/- 7779 min x pM, NS) and were strongly correlated (r = 0.83, P less than 0.001).


CONCLUSIONS
These results suggest that glucose and insulin responses to a test meal are reproducible in type II diabetic patients.
Le Floch
J P
JP
Department of Diabetology, University Hospital Henri Mondor, Créteil, France.
Baudin
E
E
Escuyer
P
P
Wirquin
E
E
Yomtov
B
B
Perlemuter
L
L
D001786:Blood Glucose / Q000378:metabolism*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D004435:Eating; D002149:Energy Intake; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood*; D008297:Male; D008875:Middle Aged; D013997:Time Factors
D001786:Blood Glucose; D007328:Insulin