[The role of the initial state of the cells in cold-induced damage].
The investigations conducted have shown three states of erythrocytes in which they are most resistant to the damaging factors in the cycle of freezing-thawing-removal of cryoprotector. Basing on the results of their own investigations and the literature data on the factors influencing the erythrocyte metabolism and resistance to acid hemolysis, the authors have made a conclusion that the structural regulation in the cell membranes play the main role in cryo-induced damage.
Stus'
L K
LK
Kuraksa
V M
VM
D000255:Adenosine Triphosphate / Q000097:blood; D001793:Blood Preservation / Q000009:adverse effects* / Q000379:methods; D015925:Cryopreservation / Q000009:adverse effects* / Q000379:methods; D004910:Erythrocyte Membrane / Q000502:physiology*; D006454:Hemoglobins / Q000032:analysis; D006461:Hemolysis / Q000502:physiology*; D006801:Humans; D009996:Osmotic Fragility / Q000502:physiology; D011188:Potassium / Q000097:blood
D006454:Hemoglobins; D000255:Adenosine Triphosphate; D011188:Potassium
Rol' iskhodnogo sostoianiia kletok v kriopovrezhdenii.