The effect of timentin in the treatment of female pelvic soft tissue infections.
Ticarcillin plus clavulanic acid (Timentin) has a broad-spectrum activity that includes gram-positive aerobes, and facultative and obligate anaerobes. Numerous studies have demonstrated that single agents, including this combination, are as efficacious as clindamycin plus an aminoglycoside in treating gynecologic soft tissue infections. Its spectrum of activity, together with its potential for treating Chlamydia trachomatis, makes it suitable for the treatment of pelvic inflammatory disease.
Faro
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Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas 77030.
D002969:Clavulanic Acids / Q000627:therapeutic use*; D003240:Connective Tissue Diseases / Q000188:drug therapy* / Q000517:prevention & control; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006801:Humans; D000292:Pelvic Inflammatory Disease / Q000188:drug therapy* / Q000517:prevention & control; D013982:Ticarcillin / Q000627:therapeutic use*; D014621:Vagina / Q000382:microbiology; D065093:beta-Lactamase Inhibitors; D001618:beta-Lactamases / Q000627:therapeutic use*
D002969:Clavulanic Acids; D065093:beta-Lactamase Inhibitors; C043215:ticarcillin-clavulanic acid; D001618:beta-Lactamases; D013982:Ticarcillin