[The depressant effect of fatty acids on the electrical and contractile activities of smooth muscles].
Inhibitory action of some fatty acids on the visceral and vascular smooth muscle of guinea pig and rat was studied by the sucrose-gap method. Potency of the inhibitory effects of fatty acids depended both on the carbon chain length and degree of saturation of acid molecule. The revealed inhibitory effect of some fatty acids (caprinic and oleinic) can be of essential physiological significance in regulation of excitation of smooth muscles.
Zagorodniuk
V P
VP
Baev
E Ia
EIa
Iaremenko
M S
MS
D000818:Animals; D003864:Depression, Chemical; D004305:Dose-Response Relationship, Drug; D004594:Electrophysiology; D005230:Fatty Acids, Nonesterified / Q000494:pharmacology*; D006168:Guinea Pigs; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000187:drug effects* / Q000502:physiology; D009130:Muscle, Smooth / Q000187:drug effects* / Q000502:physiology; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000502:physiology; D051381:Rats; D013329:Structure-Activity Relationship
D005230:Fatty Acids, Nonesterified
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