[The effect of bone marrow transplantation on the dynamic recovery of the morphofunctional properties of the pancreas in irradiated recipients].
Effect of transplantation of syngeneic bone marrow in the dose of 1 X 10(7) cell/ml on the state of pancreatic gland in lethally irradiated recipients has been studied at different stages of posttransplantation period for 3 months using 250 linear male rats G (CBA x C57B). Histological and biochemical investigation, conducted in dynamics, have shown that transplantation of native and cryopreserved bone marrow to lethally irradiated animals facilitates activation of compensatory-restoration processes manifesting themselves in mitotic division of glandular and epithelial cells, as well as optimizes exchange of carbohydrates in the irradiated organism.
Tsutsaeva
A A
AA
Glushko
T A
TA
Shatilova
L E
LE
Tupchienko
G S
GS
D000818:Animals; D001786:Blood Glucose / Q000032:analysis / Q000528:radiation effects; D016026:Bone Marrow Transplantation / Q000502:physiology*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D010179:Pancreas / Q000503:physiopathology / Q000528:radiation effects*; D011833:Radiation Injuries, Experimental / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D013997:Time Factors; D014021:Tissue Preservation; D014185:Transplantation, Isogeneic
D001786:Blood Glucose
Vliianie transplantatsii kostnogo mozga na dinamiku vosstanovleniia morfofunktsional'nykh svoĭstv podzheludochnoĭ zhelezy u obluchennykh retsipientov.