title: Isoprenyl phosphinylformates: new inhibitors of squalene synthetase.
authors.affiliation: Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, New Jersey 08543.
authors.forename: S A
authors.initials: SA
authors.lastname: Biller
authors.forename: C
authors.initials: C
authors.lastname: Forster
authors.forename: E M
authors.initials: EM
authors.lastname: Gordon
authors.forename: T
authors.initials: T
authors.lastname: Harrity
authors.forename: L C
authors.initials: LC
authors.lastname: Rich
authors.forename: J
authors.initials: J
authors.lastname: Marretta
authors.forename: C P
authors.initials: CP
authors.lastname: Ciosek
mesh_terms: D000818:Animals; D000924:Anticholesteremic Agents; D013186:Farnesyl-Diphosphate Farnesyltransferase / Q000037:antagonists & inhibitors*; D066298:In Vitro Techniques; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology; D009943:Organophosphorus Compounds / Q000138:chemical synthesis / Q000494:pharmacology*; D051381:Rats; D013329:Structure-Activity Relationship; D013729:Terpenes / Q000138:chemical synthesis / Q000494:pharmacology*
chemical_list: D000924:Anticholesteremic Agents; D009943:Organophosphorus Compounds; D013729:Terpenes; D013186:Farnesyl-Diphosphate Farnesyltransferase