[The characteristics of the retinal absorption of labelled preparations of pikamilon and GABA].
The velocity of absorption of GABA and its derivative picamilon carbon-labelled by isolated bovine retina has been studied. It is shown that maximal velocity of GABA and picamilon absorption falls at the second incubation minute, then it decreases. In all the cases the picamilon absorption velocity is higher than the GABA absorption velocity. With an increase of concentration in the incubation medium of the labeled preparation under study the absorption velocity of GABA remains practically unchanged, while that of picamilon slightly increases.
Logaĭ
I M
IM
Leus
N F
NF
Rozanova
Z A
ZA
D000042:Absorption; D000818:Animals; D002250:Carbon Radioisotopes; D002417:Cattle; D004305:Dose-Response Relationship, Drug; D066298:In Vitro Techniques; D012160:Retina / Q000378:metabolism*; D013997:Time Factors; D005680:gamma-Aminobutyric Acid / Q000031:analogs & derivatives* / Q000493:pharmacokinetics*
D002250:Carbon Radioisotopes; C044905:nicotinoyl-GABA; D005680:gamma-Aminobutyric Acid
Osobennosti pogloshcheniia setchatkoĭ mechenykh preparatov pikamilona i GAMK.