title: Intranodal leiomyoma. Another distinctive primary spindle cell neoplasm of lymph node.
abstract: Two intranodal spindle cell neoplasms are described that were interpreted as leiomyomas. Both occurred in young men. The first case involved a single peripancreatic lymph node of a patient with acquired immune deficiency syndrome (AIDS) who died of AIDS-related infection. The second case simulated a parotid gland tumor because of its location in an intraparotid lymph node in an otherwise asymptomatic patient. Both neoplasms were composed of interlacing fascicles of spindle cells with blunt-ended nuclei that seemed to arise from the walls of blood vessels. The tumor cells were immunoreactive for muscle-specific actin but were desmin negative. These leiomyomas expand the clinical and morphologic spectrum of primary spindle cell neoplasms of lymph nodes.
authors.affiliation: Department of Pathology, University of Miami School of Medicine, Florida.
authors.forename: L
authors.initials: L
authors.lastname: Starasoler
authors.forename: F
authors.initials: F
authors.lastname: Vuitch
authors.forename: J
authors.initials: J
authors.lastname: Albores-Saavedra
mesh_terms: D000328:Adult; D006801:Humans; D007150:Immunohistochemistry; D007889:Leiomyoma / Q000378:metabolism / Q000473:pathology*; D008198:Lymph Nodes / Q000378:metabolism / Q000473:pathology*; D008206:Lymphatic Diseases / Q000378:metabolism / Q000473:pathology; D008297:Male