In vivo 19F nuclear magnetic resonance brain studies of halothane, isoflurane, and desflurane. Rapid elimination and no abundant saturable binding.
Litt
L
L
Department of Anesthesia, University of California, San Francisco 94143-0648.
Lockhart
S
S
Cohen
Y
Y
Yasuda
N
N
Kim
F
F
Freire
B
B
Laster
M
M
Peterson
N
N
Taheri
S
S
Chang
L H
LH
D000777:Anesthetics / Q000493:pharmacokinetics*; D000818:Animals; D001665:Binding Sites; D001921:Brain / Q000378:metabolism*; D000077335:Desflurane; D005461:Fluorine; D006221:Halothane / Q000493:pharmacokinetics*; D007530:Isoflurane / Q000031:analogs & derivatives* / Q000493:pharmacokinetics*; D007700:Kinetics; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D009928:Organ Specificity; D013997:Time Factors
D000777:Anesthetics; D005461:Fluorine; D000077335:Desflurane; D007530:Isoflurane; D006221:Halothane