title: Trends in quantitative cancer risk assessment.
abstract: Quantitative cancer risk assessment is a dynamic field, more closely coupled to rapidly advancing biomedical research than ever before. Six areas of change and growth are identified: expansion from models of cancer initiation to a more complete picture of the total carcinogenic process; trend from curve-fitting to biologically based models; movement from upperbound estimates to best estimates, with a more complete treatment of uncertainty; increased consideration of the role of susceptibility; growing development of expert systems and decision support systems; and emerging importance of risk communication.
authors.affiliation: Biomedical and Environmental Assessment Division, Brookhaven National Laboratory, Upton, NY 11973.
authors.forename: S C
authors.initials: SC
authors.lastname: Morris
mesh_terms: D004198:Disease Susceptibility; D006801:Humans; D008954:Models, Biological; D015233:Models, Statistical; D009369:Neoplasms / Q000453:epidemiology*; D012306:Risk