[DNA examinations in gynecological cancer and breast cancer].
During the past years, automated methods for analytical cytology have produced a large quantity of data on DNA-ploidy disturbances in different types of human cancers. Flow cytometry (FCM) provides a quick and precise method for determining DNA-ploidy and distribution of the cell cycle in tumours. This paper surveys DNA-aberrations in human endometrial, cervical, ovarian and breast carcinomas, and shows that prognosis is much better for diploid than for aneuploid tumors, and that the prognostic ability of DNA-patterns is proved to be much better than that of the parameters used before, such as degree of differentiation, myometrial invasion and receptor concentrations.
Tropé
C
C
Avdeling for gynekologisk onkologi, Det Norske Radiumhospital, Oslo.
Kaern
J
J
Pettersen
E O
EO
Iversen
O E
OE
D001943:Breast Neoplasms / Q000235:genetics*; D004273:DNA, Neoplasm / Q000235:genetics*; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D010051:Ovarian Neoplasms / Q000235:genetics*; D011003:Ploidies; D011379:Prognosis; D002583:Uterine Cervical Neoplasms / Q000235:genetics*; D014594:Uterine Neoplasms / Q000235:genetics*
D004273:DNA, Neoplasm
DNA-undersøkelser ved gynekologisk kreft og brystkreft.