title: Chronic osteomyelitis due to Clostridium clostridiiforme.
abstract: We have reported a case of chronic osteomyelitis due to an unusual anaerobic organism, Clostridium clostridiiforme, a gram-positive rod that often stains gram-negative and that is frequently resistant to such drugs as cefoxitin and clindamycin. Clostridia other than those similar to C perfringens are generally not considered invasive pathogens, but our case and several similar ones show that they can be.
authors.affiliation: Division of Infectious Diseases, Mount Sinai Medical Center, Miami Beach, Fla.
authors.forename: R D
authors.initials: RD
authors.lastname: Spitzer
authors.forename: K R
authors.initials: KR
authors.lastname: Ratzan
mesh_terms: D002908:Chronic Disease; D003013:Clostridium / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000382:microbiology* / Q000503:physiopathology / Q000628:therapy; D003646:Debridement; D006801:Humans; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000382:microbiology* / Q000503:physiopathology / Q000628:therapy