Auditory nerve compound action potentials and brain stem auditory evoked potentials in patients with various degrees of hearing loss.
Click-evoked compound action potentials recorded in normal-hearing patients through a monopolar electrode placed on the intracranial portion of the eighth nerve were compared with the responses recorded in patients with high-frequency hearing loss or with high- and low-frequency hearing losses. That multiple peaks appear in the compound action potential in patients with hearing loss implies that click sounds elicit successive and separated volleys of neural excitation in the ascending auditory pathway, whereas click sounds in patients with normal hearing mainly give rise to a single volley of neural activity. This difference in the pattern of auditory nerve activity might explain why there are often multiple peaks in the brain stem auditory evoked potentials in patients with hearing loss and that the peaks are often less well-defined than peaks in patients with normal hearing.
Møller
A R
AR
Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pennsylvania.
Møller
M B
MB
Jannetta
P J
PJ
Jho
H D
HD
D001300:Audiometry, Evoked Response / Q000295:instrumentation / Q000379:methods; D005072:Evoked Potentials, Auditory; D016057:Evoked Potentials, Auditory, Brain Stem; D006311:Hearing Disorders / Q000145:classification / Q000503:physiopathology*; D006801:Humans; D007837:Latency Period, Psychological; D016343:Monitoring, Intraoperative; D012815:Signal Processing, Computer-Assisted