title: [Active immunization to exogenous and endogenous antidepressants. The formation of antibodies to biogenic amines and peptide regulators].
abstract: The active immunization of rabbits and white rats to antidepressant sydnophen results in the formation of antibodies binding norepinephrine, dophamine, serotonine as well peptide regulatory compounds: substance P, pynorphine, vasopressin and beta-endorphin. The immunization against endogenic antidepressant thyroliberin induces the formation of antibodies to the same biogenic amines and to the gamma-aminobutyric acid, oxytocin and leu encephalin. The data obtained are discussed in connection with some physiological and biochemical changes found earlier during immunization to antidepressants.
authors.forename: I P
authors.initials: IP
authors.lastname: Ashmarin
authors.forename: M F
authors.initials: MF
authors.lastname: Obukhova
authors.forename: A A
authors.initials: AA
authors.lastname: Mart'ianov
authors.forename: R A
authors.initials: RA
authors.lastname: Danilova
authors.forename: N E
authors.initials: NE
authors.lastname: Babskaia
authors.forename: Z I
authors.initials: ZI
authors.lastname: Storozheva
authors.forename: G K
authors.initials: GK
authors.lastname: Grechko
authors.forename: N V
authors.initials: NV
authors.lastname: Kuznetsova
mesh_terms: D000494:Allosteric Regulation / Q000276:immunology; D000818:Animals; D000906:Antibodies / Q000097:blood*; D000928:Antidepressive Agents / Q000276:immunology*; D001666:Binding Sites, Antibody / Q000276:immunology; D001679:Biogenic Amines / Q000276:immunology*; D004342:Drug Hypersensitivity / Q000276:immunology; D010455:Peptides / Q000276:immunology*; D011817:Rabbits; D051381:Rats; D013997:Time Factors; D014611:Vaccination / Q000379:methods*
chemical_list: D000906:Antibodies; D000928:Antidepressive Agents; D001679:Biogenic Amines; D010455:Peptides
vernacular_title: Aktivnaia immunizatsiia k ékzogennym i éndogennym antodepressantam. Obrazovanie antitel k biogennym aminam i peptidnym reguliatoram.