Necrotising colitis with perforation in diarrhoic patients treated with loperamide.
Two cases of necrotising enterocolitis with perforation occurred in patients with paralytic ileus after loperamide therapy. The possible role of loperamide in the pathogenesis of the complications is suggested.
Olm
M
M
Internal Medicine Unit, Hospital Clinico y Provincial, Barcelona, Spain.
Gonzalez
F J
FJ
Garcia-Valdecasas
J C
JC
Fuster
J
J
Bertran
A
A
Milla
J
J
D000328:Adult; D004761:Enterocolitis, Pseudomembranous / Q000139:chemically induced* / Q000503:physiopathology / Q000601:surgery; D005260:Female; D006801:Humans; D007416:Intestinal Perforation / Q000503:physiopathology / Q000601:surgery*; D008139:Loperamide / Q000009:adverse effects*
D008139:Loperamide