title: Gilles de la Tourette syndrome in the Middle East. Report of a cohort and a multiply affected large pedigree.
abstract: In a cohort of five patients from the Middle East with the Gilles de la Tourette syndrome, family history of a tic disorder or the Gilles de la Tourette syndrome was positive in three cases. In one of these there was a multiply affected pedigree spanning six generations. The phenomenology of the syndrome is the same as that described in Western reports. The familial pattern of inheritance and cross-cultural similarity emphasise the biological factors in the aetiology of the syndrome.
authors.affiliation: Institute of Neurology, UCMSM, Middlesex Hospital, London.
authors.forename: M M
authors.initials: MM
authors.lastname: Robertson
authors.forename: M R
authors.initials: MR
authors.lastname: Trimble
mesh_terms: D000328:Adult; D002648:Child; D015331:Cohort Studies; D003431:Cross-Cultural Comparison; D003430:Cross-Sectional Studies; D003937:Diagnosis, Differential; D004739:England; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008877:Middle East / Q000208:ethnology; D009460:Neurologic Examination; D010375:Pedigree; D005879:Tourette Syndrome / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology