title: [Immune response to hepatitis B vaccine produced with genetic engineering].
abstract: With the aim of evaluating the immune response obtained after the administration of the three standard doses of Hepatitis B vaccine obtained by recombinant DNA techniques (Engerix B) and the factors that may have an influence in it, we have studied 537 subjects belonging to different risk groups. The ratio of non-responders to the vaccine has been. We have found significant differences (p less than 0.001) when comparing the mean titers obtained amongst the groups of studied. We have observed a higher percentage amongst the non-responders in men, although there are not statistically significant differences between sexes. We compare the results obtained with those published by other groups.
authors.affiliation: Servicio de Medicina Preventiva, Hospital de Bellvitge Prínceps d'Espanya, Hospitalet de Llobregat, Barcelona.
authors.forename: J M
authors.initials: JM
authors.lastname: Ramón Torrell
authors.forename: C
authors.initials: C
authors.lastname: Micheo Salas
authors.forename: C
authors.initials: C
authors.lastname: Cerdó Goicouria
authors.forename: I
authors.initials: I
authors.lastname: Casas García
authors.forename: J M
authors.initials: JM
authors.lastname: Escribá Jordana
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006509:Hepatitis B / Q000517:prevention & control*; D006510:Hepatitis B Antibodies / Q000096:biosynthesis / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D014614:Vaccines, Synthetic / Q000008:administration & dosage / Q000276:immunology*; D014761:Viral Hepatitis Vaccines / Q000008:administration & dosage / Q000276:immunology*
chemical_list: D006510:Hepatitis B Antibodies; D014614:Vaccines, Synthetic; D014761:Viral Hepatitis Vaccines
vernacular_title: Respuesta inmunitaria a la vacuna contra la hepatitis B obtenida por ingeniería genética.