[Infections and systemic lupus erythematosus. Analysis of risk factors and prognosis. A prospective study (1979-1988)].
We have prospectively studied 48 patients previously diagnosed of systemic lupus erythematosus over a mean follow up period of 5.8 years of which 28 presented 36 episodes of infection and 20 did not develop infections. Urinary infections were the most frequent kind of infection followed by pneumonia and bacteriemia; the most frequently isolated microorganism responsible for those infections were E. colii, staphylococcus aureu and P. mirabillis. We have found a risk factors that and impared renal function an steroid treatment over 20 mg/day were significantly associated with a increasing number of infectious precesses. On the contrary, we have observed that only a bad and critical clinical situation had prognostic value and was significantly associated with an increased mortality.
Gómez
J
J
Hospital Virgen de la Arrixaca, Departamento de Medicina Interna, Murcia.
Palazón
D
D
Ortega
G
G
Lucas
E
E
Bru
M
M
Campillo
M
M
Torralba
M
M
Canteras
M
M
Sánchez Gascón
F
F
D000328:Adult; D005260:Female; D006801:Humans; D007239:Infections / Q000150:complications* / Q000453:epidemiology; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008297:Male; D011379:Prognosis; D011446:Prospective Studies; D012307:Risk Factors
Infecciones y lupus eritematoso sistémico. Análisis de factores de riesgo y pronóstico. Estudio prospectivo (1979-1988).