title: [Group- and type-specific antibodies to the gag-gene protein p26 of the human immunodeficiency virus immunological type 2 in infected patients].
abstract: The immunoreactivity of serum samples from HIV-2 infected persons was studied by radioimmunoprecipitation assay (RIPA) in homo- and heterotypic variants. In homotypic RIPA all sera studied have precipitated the viral glycoprotein with the high molecular weight, gp170. Some samples were active for gag-gene products, p57 and p26 in homotypic RIPA. Most these samples were also active for heterotypic gag-protein of HIV-1 serotype, p55 and p24. On the other hand anti-gag reactivity of one sample was limited only by homotypic activity. Some causes of this phenomena as well as its significance for serodiagnosis of HIV infection are discussed.
authors.forename: S Iu
authors.initials: SIu
authors.lastname: Kliushnik
authors.forename: L M
authors.initials: LM
authors.lastname: Selimova
authors.forename: T V
authors.initials: TV
authors.lastname: Veselovskaia
authors.forename: V M
authors.initials: VM
authors.lastname: Zaĭdes
mesh_terms: D000918:Antibody Specificity / Q000276:immunology*; D015683:Gene Products, gag / Q000276:immunology*; D015483:HIV Antibodies / Q000097:blood*; D015488:HIV Antigens; D015658:HIV Infections / Q000276:immunology*; D015498:HIV-2 / Q000276:immunology*; D006801:Humans; D015531:Radioimmunoprecipitation Assay; D054301:gag Gene Products, Human Immunodeficiency Virus
chemical_list: D015683:Gene Products, gag; D015483:HIV Antibodies; D015488:HIV Antigens; D054301:gag Gene Products, Human Immunodeficiency Virus; C065558:gag protein p26, Human immunodeficiency virus
vernacular_title: Gruppo- i tipospetsificheskie antitela k belku p26 gena gag virusa immunodefitsita cheloveka 2-go immunologicheskogo tipa u infitsirovannykh.