title: Serum ferritin spectrotypes in patients with heterozygous beta-thalassaemia.
abstract: Serum ferritin spectrotypes from patients heterozygous for beta-thalassaemia were determined after agarose isoelectric focusing followed by radio-immunofixation with anti-ferritin antibody. Multivariate analysis demonstrated a specific spectrotype for heterozygous beta-thalassaemia. This spectrotype was shown to be different from those in hereditary spherocytosis and idiopathic haemochromatosis. Statistical discrimination reached 100% of well-classified patients between these pathological conditions.
authors.affiliation: Laboratoire Central des Isotopes, Hôpital Edouard Herriot, Lyon, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Lasne
authors.forename: A
authors.initials: A
authors.lastname: Francina
authors.forename: O
authors.initials: O
authors.lastname: Benzerara
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016002:Discriminant Analysis; D005260:Female; D005293:Ferritins / Q000097:blood* / Q000737:chemistry; D006579:Heterozygote; D006801:Humans; D007525:Isoelectric Focusing; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012016:Reference Values; D013789:Thalassemia / Q000097:blood*
chemical_list: D005293:Ferritins