Unsuspected quinine intoxication presenting as acute deafness and mutism.
A case of unsuspected quinine overdose is reported in a 14-year-old girl. Presenting symptoms included deafness and mutism. Diagnosis was delayed for approximately 4 hours because of the absence of an accurate history. Case details, laboratory values, and hospital course are discussed. Signs of cinchonism and common ototoxins are discussed. Strategies for the management of quinine overdose are reviewed.
Schonwald
S
S
Emergency Administration, Brigham & Women's Hospital, Boston, MA.
Shannon
M
M
D000293:Adolescent; D003638:Deafness / Q000139:chemically induced*; D005260:Female; D006801:Humans; D009155:Mutism / Q000139:chemically induced*; D011041:Poisoning / Q000175:diagnosis / Q000628:therapy; D011803:Quinine / Q000506:poisoning*; D012640:Seizures / Q000139:chemically induced*; D019966:Substance-Related Disorders / Q000628:therapy
D011803:Quinine