title: Idiopathic calcinosis of the scrotum: scanning electron microscopic study with X-ray microanalysis.
abstract: In a 31-year-old man 12 nodules up to 1 cm in diameter were observed in the scrotum; these had developed over 3 years. Energy-dispersive x-ray analysis of the dermal foci showed a high content of calcium and phosphorus even in nodules smaller than 1 mm in diameter. No increased mineral deposition was observed in the surrounding connective tissue, however. Scanning electron microscopy revealed finely granulated crystals, and cellular remnants giving rise to development of calcified nodules were disclosed. The results support the hypothesis of a degenerative origin of scrotal calcinosis.
authors.affiliation: Department of Pathology, Medical Faculty, Technical University, Aachen, Germany.
authors.forename: L
authors.initials: L
authors.lastname: Füzesi
authors.forename: G
authors.initials: G
authors.lastname: Hollweg
authors.forename: W
authors.initials: W
authors.lastname: Lagrange
authors.forename: C
authors.initials: C
authors.lastname: Mittermayer
mesh_terms: D000328:Adult; D002114:Calcinosis / Q000378:metabolism / Q000473:pathology*; D002118:Calcium / Q000032:analysis; D004577:Electron Probe Microanalysis; D005832:Genital Diseases, Male / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D008297:Male; D008855:Microscopy, Electron, Scanning; D010758:Phosphorus / Q000032:analysis; D012611:Scrotum / Q000648:ultrastructure*
chemical_list: D010758:Phosphorus; D002118:Calcium