Serum ferritin spectrotypes in patients with heterozygous beta-thalassaemia.
Serum ferritin spectrotypes from patients heterozygous for beta-thalassaemia were determined after agarose isoelectric focusing followed by radio-immunofixation with anti-ferritin antibody. Multivariate analysis demonstrated a specific spectrotype for heterozygous beta-thalassaemia. This spectrotype was shown to be different from those in hereditary spherocytosis and idiopathic haemochromatosis. Statistical discrimination reached 100% of well-classified patients between these pathological conditions.
Lasne
Y
Y
Laboratoire Central des Isotopes, Hôpital Edouard Herriot, Lyon, France.
Francina
A
A
Benzerara
O
O
D000293:Adolescent; D000328:Adult; D000368:Aged; D016002:Discriminant Analysis; D005260:Female; D005293:Ferritins / Q000097:blood* / Q000737:chemistry; D006579:Heterozygote; D006801:Humans; D007525:Isoelectric Focusing; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012016:Reference Values; D013789:Thalassemia / Q000097:blood*
D005293:Ferritins