Alveolar soft-part sarcoma of the uterine corpus: histological, immunocytochemical and ultrastructural study of a case.
A case of alveolar soft-part sarcoma located in the uterine corpus is reported. It was an incidental finding in the hysterectomy specimen of a 40-year-old woman. Light and electron microscopic examination revealed periodic-acid-Schiff-positive, diastase-resistant, membrane-bound cytoplasmic granules and crystalloids. Tumour cells expressed immunoreactivity with vimentin, desmin, cytokeratins, NK1/C3 and HMB-45 antibodies. Four years postoperatively, the patient is still alive without evidence of disease. Differential diagnoses, immunocytochemistry and clinical management of uterine alveolar soft-part sarcoma are discussed and the literature reviewed.
Guillou
L
L
Institut Universitaire de Pathologie, Lausanne, Switzerland.
Lamoureux
E
E
Masse
S
S
Costa
J
J
D000328:Adult; D000911:Antibodies, Monoclonal / Q000032:analysis; D003893:Desmin / Q000032:analysis; D005260:Female; D006801:Humans; D012509:Sarcoma / Q000276:immunology / Q000473:pathology* / Q000648:ultrastructure; D014594:Uterine Neoplasms / Q000276:immunology / Q000473:pathology* / Q000648:ultrastructure; D014746:Vimentin / Q000032:analysis
D000911:Antibodies, Monoclonal; D003893:Desmin; D014746:Vimentin