title: [Intranasal midazolam in pediatric ophthalmology].
abstract: Intranasal midazolam was tested in pediatric patients undergoing ophthalmological examination. 15 children aged 3.5 months to 10 years received 0.35-0.5 mg.kg-1 intranasal midazolam in association with a corneal anesthesia. The onset of sedation was rapid and permitted adequate ocular examination in all cases. In 8 of 15 cases where surgery followed immediately, the induction of inhalational anesthesia was easier. No local or general adverse reaction was noted. This non-invasive method of anesthesia may be compared to the intrarectal administration of midazolam, but the rapid onset of sedation and a cleaner route seem more suitable in surgical environment.
authors.affiliation: Service d'Anesthésie-Réanimation, Fondation ophtalmologique A. de-Rothschild, Paris.
authors.forename: D
authors.initials: D
authors.lastname: Gobeaux
authors.forename: F
authors.initials: F
authors.lastname: Sardnal
authors.forename: H
authors.initials: H
authors.lastname: Cohn
authors.forename: O
authors.initials: O
authors.lastname: Lequoy
mesh_terms: D000281:Administration, Intranasal; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008874:Midazolam / Q000008:administration & dosage*; D009885:Ophthalmology / Q000379:methods*; D010372:Pediatrics
chemical_list: D008874:Midazolam
vernacular_title: Midazolam intranasal en ophtalmologie pédiatrique.