title: Novel t(15;19)(q15;p13) chromosome abnormality in a thymic carcinoma.
abstract: A 22-year-old female with a thymic carcinoma is reported. The tumor was refractory to both chemotherapy and irradiation. The patient died with an aggressive clinical course. Cytogenetic study showed that the tumor cells had a chromosome translocation, t(15;19)(q15;p13), which was not identified previously in human cancer.
authors.affiliation: Department of Medicine, Kochi Medical School, Japan.
authors.forename: I
authors.initials: I
authors.lastname: Kubonishi
authors.forename: N
authors.initials: N
authors.lastname: Takehara
authors.forename: J
authors.initials: J
authors.lastname: Iwata
authors.forename: H
authors.initials: H
authors.lastname: Sonobe
authors.forename: Y
authors.initials: Y
authors.lastname: Ohtsuki
authors.forename: T
authors.initials: T
authors.lastname: Abe
authors.forename: I
authors.initials: I
authors.lastname: Miyoshi
mesh_terms: D000328:Adult; D002884:Chromosomes, Human, Pair 15; D002888:Chromosomes, Human, Pair 19; D005260:Female; D006801:Humans; D007621:Karyotyping; D008479:Mediastinal Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D013953:Thymus Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic