title: Immune responses to intramammary infusion with soluble (ovalbumin) and particulate (S uberis) antigens in the preparturient bovine udder.
abstract: Pregnant non-lactating cows were immunised by intramammary infusion with killed Streptococcus uberis into one quarter and ovalbumin into another, at one week (group 2) or one week and two weeks (group 1) before the expected date of parturition. A small IgG1 and IgG2 antibody response to ovalbumin was detected in the serum of these cows. There was also a small increase in IgG1 and IgA serum antibody activity to S uberis. In whey the response was restricted to IgA with activity to S uberis. The IgA antibody response to S uberis in group 1 was significantly greater in the quarter immunised with bacteria than that of the control quarters for up to two months after calving. In contrast, the serum IgA response was short or absent in a number of animals.
authors.affiliation: Department of Veterinary Medicine, University of Bristol, Langford.
authors.forename: T O
authors.initials: TO
authors.lastname: Nashar
authors.forename: C R
authors.initials: CR
authors.lastname: Stokes
authors.forename: P J
authors.initials: PJ
authors.lastname: Cripps
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology*; D002417:Cattle; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005260:Female; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis*; D007075:Immunoglobulin M / Q000032:analysis; D007263:Infusions, Parenteral; D008321:Mammary Glands, Animal / Q000382:microbiology; D008894:Milk Proteins / Q000032:analysis; D010047:Ovalbumin / Q000276:immunology*; D011247:Pregnancy; D013291:Streptococcus / Q000276:immunology*
chemical_list: D000942:Antigens, Bacterial; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008894:Milk Proteins; D010047:Ovalbumin