[Assessment of criteria for forming follow-up groups of patients at high risk for ulcerogenesis in ambulatory care].
A method of clinico-laboratory examinations to reveal persons at high risk for the development of duodenal ulcer, suitable for wide use during prophylactic medical screenings was devised. The rise of the levels of serum pepsinogen-I, pepsin and hexosamines in the urine, being of prognostic importance as applicable to ulcerogenesis, was the most significant indicator in screening risk group patients. During 3 to 5 years of the screened group follow-up and carrying out health measures, peptic ulcer was ascertained in 8.4% of the patients with chronic gastroduodenitis. Of these, 66.6% had initially suffered from pylorobulbitis. It is shown that there is a real opportunity of preventing ulcer formation in patients with chronic primary gastroduodenitis under outpatient conditions.
Minushkin
O N
ON
Elizavetina
G A
GA
Chorbinskaia
S A
SA
Zverkov
I V
IV
Bredikhina
N A
NA
Vlasova
M N
MN
Smirnova
L M
LM
Berkovich
N M
NM
D000293:Adolescent; D000328:Adult; D000554:Ambulatory Care Facilities / Q000379:methods*; D015415:Biomarkers / Q000097:blood / Q000652:urine; D004381:Duodenal Ulcer / Q000150:complications / Q000175:diagnosis*; D005260:Female; D005500:Follow-Up Studies; D005767:Gastrointestinal Diseases / Q000150:complications; D006595:Hexosamines / Q000652:urine; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D010434:Pepsin A / Q000652:urine; D010435:Pepsinogens / Q000097:blood; D011379:Prognosis; D012307:Risk Factors
D015415:Biomarkers; D006595:Hexosamines; D010435:Pepsinogens; D010434:Pepsin A
Otsenka kriteriev formirovaniia grupp nabliudeniia sredi lits s faktorami vysokogo riska ul'tserogeneza v usloviiakh polikliniki.