title: Treatment planning for ferromagnetic seed heating.
abstract: Computer simulations of ferromagnetic seed heating have been performed for the case of a single constant-temperature ferromagnetic seed. Results obtained from both 2-dimensional and 3-dimensional thermal models are compared to determine the appropriate use and limitations of the 2-dimensional model for the case of array implants. It has been determined that the 2-dimensional model that assumes infinite extent of the ferromagnetic seed(s) is applicable for calculating the thermal distribution in any plane perpendicular to the axes of the implant(s) up to 1 cm from the ends of the seed(s). The feasibility of spatially interspersed ferromagnetic and radioactive seeds for concurrent hyperthermia and brachytherapy has also been studied. The steady-state temperature distribution within an array of ferromagnetic seed implant has been examined as a function of implant spacing and blood perfusion rate. The results have been quantified in generalized histograms that are readily applicable to pre-treatment planning.
authors.affiliation: Department of Radiation Oncology, University of Rochester, NY 14642.
authors.forename: R B
authors.initials: RB
authors.lastname: Chin
authors.forename: P R
authors.initials: PR
authors.lastname: Stauffer
mesh_terms: D003198:Computer Simulation; D005290:Ferric Compounds / Q000627:therapeutic use*; D006801:Humans; D006979:Hyperthermia, Induced / Q000295:instrumentation / Q000379:methods*
chemical_list: D005290:Ferric Compounds; C001215:ferrite