title: Organization and transcription of canine (CAC)n sequences.
abstract: Twenty-nine canine DNA samples, including samples from 11 members of an autosomal recessive retinal degeneration pedigree, were fingerprinted with a (CAC)n probe using a chemiluminescent method. Sixteen polymorphic bands were identified in the two pedigrees. Nine polymorphic bands were scored in one pedigree; seven polymorphic bands were scored in the other pedigree. None were sex-linked. Hybridization of the (CAC)n probe to total and poly A+ RNAs from different canine tissues revealed a prominent polyadenylated message at 6 kb that was present in the retina, spleen, and kidney but not in the liver or heart.
authors.affiliation: Section of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010.
authors.forename: B
authors.initials: B
authors.lastname: Hershfield
authors.forename: L
authors.initials: L
authors.lastname: Inouye
authors.forename: G
authors.initials: G
authors.lastname: Chader
authors.forename: H
authors.initials: H
authors.lastname: Ripps
authors.forename: G
authors.initials: G
authors.lastname: Aguirre
mesh_terms: D000818:Animals; D001483:Base Sequence; D004247:DNA; D016172:DNA Fingerprinting; D004285:Dogs / Q000235:genetics*; D005260:Female; D008163:Luminescent Measurements; D008297:Male; D008969:Molecular Sequence Data; D015345:Oligonucleotide Probes; D010375:Pedigree; D011110:Polymorphism, Genetic; D012162:Retinal Degeneration / Q000235:genetics / Q000662:veterinary; D014158:Transcription, Genetic
chemical_list: D015345:Oligonucleotide Probes; D004247:DNA