In vitro and in vivo inhibition of Dermatophilus congolensis by coagulase-negative antibiotic-producing staphylococci from pigs.
When tested on solid media the growth of 19 Dermatophilus congolensis strains was inhibited by antibiotic-producing staphylococci isolated from pigs. Two strains, D congolensis D11 and D15, which were very sensitive to the producers and caused lesions of dermatophilosis in a mouse model, were further used to investigate the ability of the producers to inhibit lesion formation by the strains of D congolensis. The simultaneous application of the antibiotic-producing staphylococci and D congolensis suppressed formation of the lesions in the mouse.
Zaria
L T
LT
Department of Microbial Diseases, United Medical School, St Thomas' Hospital, London.
D000192:Actinomycetales / Q000254:growth & development*; D000193:Actinomycetales Infections / Q000517:prevention & control; D000818:Animals; D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D003030:Coagulase; D006131:Growth Inhibitors / Q000096:biosynthesis; D013210:Staphylococcus / Q000378:metabolism*; D013552:Swine
D000900:Anti-Bacterial Agents; D003030:Coagulase; D006131:Growth Inhibitors