[The effect of pyrogens on the ultrastructure of the reticular nuclei and large raphe nucleus of the medulla oblongata in the cat].
Investigation of ultrastructure of reticular nuclei in the large nucleus of the raphe medullae oblongatae has revealed a close position of some neurons to the vascular endothelium. Intravenous administration of exo- or endogenic pyrogens produces dilatation of the perivascular space and appearance of lipid phagocytes in it. Simultaneously in neurons, glio- and endotheliocytes lysosomes, lipofuscin and vacuoles are revealed. The changes detected are transitory and not specific for the agents applied.
Netukova
N I
NI
D000818:Animals; D002415:Cats; D006801:Humans; D007375:Interleukin-1 / Q000494:pharmacology; D008070:Lipopolysaccharides / Q000494:pharmacology; D008526:Medulla Oblongata / Q000187:drug effects* / Q000648:ultrastructure; D008854:Microscopy, Electron; D009474:Neurons / Q000187:drug effects / Q000648:ultrastructure; D011749:Pyrogens / Q000494:pharmacology*; D011903:Raphe Nuclei / Q000187:drug effects* / Q000648:ultrastructure; D012485:Salmonella typhi
D007375:Interleukin-1; D008070:Lipopolysaccharides; D011749:Pyrogens; C009136:pyrogenal
Vliianie pirogenov na ul'trastrukturu retikuliarnykh iader i bol'shogo iadra shva prodolgovatogo mozga koshki.