title: [Changes in the levels of total and protein-bound hydroxyproline in the serum and urine of patients with cancer of the larynx after radiotherapy].
abstract: The serum concentration of total and protein-bound hydroxyproline as well as urinary hydroxyproline excretion were measured in 52 laryngeal cancer patients before, during and after irradiation. The modified colorimetric method described by Prockop and Udenfriend was used. After irradiation the increased total hydroxyproline concentration and excretion were observed, whereas no changes in serum protein-bound hydroxyproline were stated. Any correlation between the results of therapy and serum/urinary hydroxyproline levels were observed.
authors.affiliation: Zakładu Biochemii Klinicznej i Toksykologii Srodowiska AM w Lublinie.
authors.forename: J
authors.initials: J
authors.lastname: Tomaszewski
authors.forename: J
authors.initials: J
authors.lastname: Klatka
authors.forename: S
authors.initials: S
authors.lastname: Klonowski
mesh_terms: D000328:Adult; D000368:Aged; D003124:Colorimetry; D006801:Humans; D006909:Hydroxyproline / Q000378:metabolism* / Q000528:radiation effects; D007822:Laryngeal Neoplasms / Q000378:metabolism* / Q000473:pathology / Q000532:radiotherapy; D008875:Middle Aged; D009367:Neoplasm Staging; D011485:Protein Binding / Q000528:radiation effects
chemical_list: D006909:Hydroxyproline
vernacular_title: Zmiany stezenia hydroksyproliny całkowitej i białkowej w surowicy i moczu u chorych napromienianych z powodu raka krtani.