title: Phototoxicity due to Cachrys libanotis.
abstract: After classification and identification of the plant, the alcoholic extract of Cachrys libanotis L. was analysed in order to identify the phototoxic agents. The substances responsible for photodermatitis were found to be 4 furocoumarins, of which 3 have been clearly identified, namely 5-methoxy-, 8-methoxy- and 5,8-dimethoxypsoralen. The structure of a 4th compound was not completely defined.
authors.affiliation: Clinica Dermatologica, Facoltà di Medicina e Chirurgia, Università di Sassari, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Ena
authors.forename: R
authors.initials: R
authors.lastname: Cerri
authors.forename: G
authors.initials: G
authors.lastname: Dessi
authors.forename: P M
authors.initials: PM
authors.lastname: Manconi
authors.forename: A D
authors.initials: AD
authors.lastname: Atzei
mesh_terms: D000078223:5-Methoxypsoralen; D000328:Adult; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D005638:Fruit / Q000032:analysis; D011564:Furocoumarins / Q000032:analysis*; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007558:Italy; D008297:Male; D008730:Methoxsalen / Q000032:analysis; D010787:Photosensitivity Disorders / Q000209:etiology*; D010944:Plants / Q000032:analysis / Q000145:classification
chemical_list: D011564:Furocoumarins; C015304:isopimpinellin; D000078223:5-Methoxypsoralen; D008730:Methoxsalen