title: Target-point combination of MR images.
abstract: A method is described for combining multiple magnetic resonance images of the same anatomic slice to produce a single image which incorporates the favorable contrast features of each of the original images. The target-point method is a general method that includes linear combination as a subset and is designed to deal with the clinical need to maximize the contrast-to-noise ratio between several pairs of tissue simultaneously. Although it is intrinsically a nonlinear method, noise propagates approximately uniformly into the combined image. In examples of brain images the target-point method produces images with higher mutual contrast than the first principal component weighted sun image.
authors.affiliation: Department of Radiological Sciences, University of California, Irvine 92717.
authors.forename: R B
authors.initials: RB
authors.lastname: Buxton
authors.forename: F
authors.initials: F
authors.lastname: Greensite
mesh_terms: D001921:Brain / Q000033:anatomy & histology*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*