[Prognostic value of the cellular expression of carcinoembryonic antigen (CEA) in gastric adenocarcinoma].
Fifty resected gastric adenocarcinomas were studied retrospectively to evaluate survival factors. Eleven different criteria were assessed using multivariate analysis. Only two criteria were significant: 1--cellular expression of carcinoembryonic antigen (p less than 0.0001 - CCR = 1.48) 2--intravascular or lymphatic tumor emboli (p less than 0.006 - CCR = 2.06). Thus, it is suggested that in addition to the various prognostic factors available to the surgical pathologist, the presence of cellular expression of carcinoembryonic antigen in tumor tissue will aid in predicting the prognosis of patients with gastric carcinoma.
Monges
G
G
Service d'Anatomie Pathologique, Institut Paoli-Calmettes, Marseille.
Penault
F
F
Seitz
J F
JF
Sandoval
M
M
Delpero
J R
JR
Houvenaeghel
G
G
Giovanini
M
M
Gouvernet
J
J
Hassoun
J
J
D000230:Adenocarcinoma / Q000737:chemistry* / Q000401:mortality / Q000473:pathology; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000911:Antibodies, Monoclonal; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D009360:Neoplastic Cells, Circulating / Q000737:chemistry; D011379:Prognosis; D012189:Retrospective Studies; D009418:S100 Proteins / Q000032:analysis; D013274:Stomach Neoplasms / Q000737:chemistry* / Q000401:mortality / Q000473:pathology; D015996:Survival Rate
D000911:Antibodies, Monoclonal; D002272:Carcinoembryonic Antigen; D009418:S100 Proteins
Valeur pronostique de l'expression cellulaire de l'antigène carcinoembryonnaire (ACE) dans les adénocarcinomes gastriques.