title: Susceptibility of anaerobic bacteria to BAY v 3522.
abstract: The activity of BAY v 3522 against 340 strains of anaerobic bacteria was determined by an agar dilution method. Its activity was compared with those of amoxicillin, amoxicillin-clavulanate, cefaclor, cefadroxil, cefoxitin, cefuroxime, cephalexin, clindamycin, doxycycline, and metronidazole. BAY v 3522, amoxicillin-clavulanate, cefoxitin, clindamycin, and metronidazole were the most active agents tested. On the basis of these results, BAY v 3522 appears to have an antibacterial activity that warrants further investigation in clinical trials.
authors.affiliation: Department of Microbiology, Huddinge University Hospital, Stockholm, Sweden.
authors.forename: C E
authors.initials: CE
authors.lastname: Nord
authors.forename: M
authors.initials: M
authors.lastname: Rylander
authors.forename: S R
authors.initials: SR
authors.lastname: Norrby
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001421:Bacteria, Anaerobic / Q000187:drug effects*; D052160:Benzothiazoles; D002511:Cephalosporins / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests
chemical_list: D000900:Anti-Bacterial Agents; D052160:Benzothiazoles; D002511:Cephalosporins; C064738:Bay v 3522