[Eosinophilia as a possible heart damaging factor in systemic scleroderma in children].
Altogether 173 children with systemic scleroderma (SSD) were examined. Of these, 45 were with eosinophilia. It was discovered that associated SSD and eosinophilia ran a course marked by more well-defined exudative reactions, with the heart being injured more frequently and gravely. A correlation was noted between the "sclerodermic" heart and the eosinophil count in the peripheral blood. The relationship between eosinophilia and the content of the total serum IgE in SSD is discussed as is the role of age-associated and constitutional factors in the development of eosinophilia in SSD children.
Deliagin
V M
VM
Uvarova
N N
NN
Kovaleva
V N
VN
D000367:Age Factors; D002648:Child; D004802:Eosinophilia / Q000150:complications* / Q000209:etiology; D006331:Heart Diseases / Q000209:etiology*; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D012595:Scleroderma, Systemic / Q000150:complications* / Q000276:immunology
D007073:Immunoglobulin E
Eozinofiliia kak vozmozhnyĭ kardiopovrezhdaiushchiĭ faktor pri sistemnoĭ sklerodermii u deteĭ.