title: Prosthesis-induced synovitis simulating villonodular synovitis.
abstract: Prosthetic arthroplasties are performed frequently in arthritic patients. The usual causes of prosthetic failures are loosening, infection, subluxation, or fracture. A 65-year-old man with total knee arthroplasty illustrates the complication of prosthetic synovitis developing 5 years after metal-polyethylene arthroplasty. Double contrast arthrography revealed nodular synovial filling defects. Arthrotomy and hematoxylin-and-eosin-stained histological sections of the synovium showed nonpigmented villonodular synovitis (VS). Giant cells and polyethylene particles were observed by polarized light within the synovium.
authors.affiliation: Rheumatology Section, W.S. Middleton Memorial VA Hospital, Madison.
authors.forename: L A
authors.initials: LA
authors.lastname: Karl
authors.forename: W R
authors.initials: WR
authors.lastname: Sundstrom
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D006801:Humans; D007720:Knee Prosthesis; D008297:Male; D008670:Metals; D011095:Polyethylenes; D011475:Prosthesis Failure; D013585:Synovitis / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D013586:Synovitis, Pigmented Villonodular / Q000175:diagnosis*
chemical_list: D008670:Metals; D011095:Polyethylenes