Hyaluronic acid in a cardiac myxoma: a biochemical and histological analysis.
Cardiac myxoma is the most common primary tumor of the heart. This tumor has a gelatinous stroma that is thought to be composed of glycosaminoglycans, the classical acid mucopolysaccharide ground substance. We examined both biochemically and histologically the hyaluronic acid in a case of cardiac myxoma using a newly developed hyaluronic acid-binding protein probe. We observed that hyaluronic acid was localized in the amorphous stroma and occurred at levels 30 times that found in normal atrial septum.
Longaker
M T
MT
Department of Surgery, University of California, San Francisco 94143.
Chiu
E S
ES
Hendin
B
B
Finkbeiner
W E
WE
Stern
R
R
D006338:Heart Neoplasms / Q000737:chemistry*; D006801:Humans; D006820:Hyaluronic Acid / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D009232:Myxoma / Q000737:chemistry*
D006820:Hyaluronic Acid