title: [The effect of intravenous streptokinase on selected echocardiographic and clinical parameters of patients followed up for 2 years after myocardial infarction].
abstract: 54 patients (pts) aged 70 years or younger with acute transmural myocardial infarction and onset of chest pain less than 12 hours were assigned in a blind manner to streptokinase group (SK), 54--to control group, 34 pts received intravenous infusion of 1,500,000 IU of SK/hour, 14 pts--2,000,000 IU/hour, and 6 pts--3,000,000 IU/2.5 hours. Intravenous streptokinase reduced left ventricular (LV) asynergy during hospital phase, decreased LV thrombus formation, and limited myocardial necrosis size 2 years after myocardial infarction. Its effect on clinical course and prognosis after myocardial infarction was of small importance.
authors.affiliation: I Kliniki Kardiologii Instytutu Kardiologii AM im. K. Marcinkowskiego w Poznaniu.
authors.forename: K
authors.initials: K
authors.lastname: Poprawski
authors.forename: I
authors.initials: I
authors.lastname: Piszczek
authors.forename: T
authors.initials: T
authors.lastname: Smukowski
authors.forename: R
authors.initials: R
authors.lastname: Ochotny
authors.forename: K
authors.initials: K
authors.lastname: Błaszyk
authors.forename: S
authors.initials: S
authors.lastname: Paradowski
mesh_terms: D000368:Aged; D004452:Echocardiography; D005500:Follow-Up Studies; D006801:Humans; D007262:Infusions, Intravenous; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011379:Prognosis; D013300:Streptokinase / Q000627:therapeutic use*
chemical_list: D013300:Streptokinase
vernacular_title: Wpływ podanej dozylnie streptokinazy na wybrane parametry echokardiograficzne i kliniczne oraz losy chorych w okresie 2 lat po zawale serca.