[Autoimmune hemolytic anemia associated with severe giant cell hepatitis].
Autoimmune hemolytic anemia and severe giant cell hepatitis is an very uncommon association. Two patients aged 5 months and 2 years developed severe anemia, jaundice, hepatomegaly and splenomegaly. Laboratory tests demonstrated autoimmune hemolytic anemia and elevated amino-transferases. Diffuse giant cell transformation and distorted architecture was seen in liver biopsy. One patient had a cytomegalovirus infection. Early steroid therapy did not prevent fatal course with liver failure in one patient.
Camarero Salcés
C
C
Servicio de Pediatría, Hospital Ramón y Cajal, Madrid.
Vasconez Muñoz
F
F
San José Hernando
D
D
Morales
P
P
Suárez Cortina
L
L
Parra Vázquez
C
C
Escobar Castro
H
H
Muñoz Villa
A
A
D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications* / Q000276:immunology; D006505:Hepatitis / Q000150:complications* / Q000276:immunology; D006801:Humans; D007223:Infant; D008297:Male
Anemia hemolítica autoinmune y hepatitis severa con transformación giganto celular.