title: Ventricular dysfunction following direct-current shock atrioventricular junction ablation.
abstract: Catheter-induced His bundle ablation for refractory supraventricular arrhythmias is most commonly performed with direct-current shock energy of 200-300 joules. The high energy pulse delivered by direct-current shock produces a lesion in the atrioventricular node by fulguration, with the residual energy being dissipated as a pressure wave. The effect of direct-current shock His bundle ablation on global and regional ventricular function was assessed in 14 consecutive patients by radionuclide ventriculography performed before and after ablation and again three months later. All studies were performed with ventricular pacing at 110 bpm. Global left ventricular ejection fraction was found to be significantly reduced at the three month study (0.43 +/- 0.03 vs 0.50 +/- 0.03, pre ablation, p = 0.02). A significant reduction in wall-motion score was also seen in six of the seven patients who had normal wall motion in pacing rhythm prior to ablation. Deterioration was mainly seen at the left and right ventricular apices. The observed reduction in ventricular function that follows direct-current shock His bundle ablation may result from myocardial damage from electro-coagulation or from barotrauma and supports continued investigation into alternative, less traumatic energy sources for the procedure.
authors.affiliation: Royal Melbourne Hospital, Vic., Australia.
authors.forename: R J
authors.initials: RJ
authors.lastname: Warren
authors.forename: J K
authors.initials: JK
authors.lastname: Vohra
authors.forename: W
authors.initials: W
authors.lastname: Chan
authors.forename: M
authors.initials: M
authors.lastname: Lichtenstein
authors.forename: H G
authors.initials: HG
authors.lastname: Mond
authors.forename: D
authors.initials: D
authors.lastname: Hunt
mesh_terms: D000328:Adult; D002036:Bundle of His / Q000601:surgery*; D002304:Cardiac Pacing, Artificial; D004564:Electrocoagulation / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D015637:Gated Blood-Pool Imaging; D006321:Heart / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D009200:Myocardial Contraction / Q000502:physiology; D013318:Stroke Volume / Q000502:physiology; D013617:Tachycardia, Supraventricular / Q000601:surgery*; D013997:Time Factors; D016277:Ventricular Function, Left / Q000502:physiology*