[Lipid peroxidation and the trace element content of the blood in patients with lichen ruber planus of the oral mucosa].
Examinations of 143 patients with lichen planus of the buccal mucosa and of 45 normal subjects included studies of lipid peroxidation (LPO) activity and of anti-radical defence system, as well as measurements of a number of blood trace elements. Plasma and red cell LPO intensity in the patients was several times higher than in the controls. Plasma glutathione peroxidase activity was found essentially reduced in the patients, whereas in red cells this activity surpassed 5 times the normal values. Glutathione reductase plasma activity was elevated and its red cell activity decreased. These findings indicate significant LPO disorders in the patients with lichen planus; their blood trace element levels were also found changed.
Skliar
V E
VE
Kondrat'eva
N I
NI
Shafran
L M
LM
D000328:Adult; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D006801:Humans; D008010:Lichen Planus / Q000097:blood* / Q000209:etiology; D015227:Lipid Peroxidation; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000097:blood* / Q000209:etiology; D009061:Mouth Mucosa; D014131:Trace Elements / Q000097:blood*
D014131:Trace Elements
Sostoianie perekisnogo okisleniia lipidov i soderzhanie mikroélementov v krovi u bol'nykh krasnym ploskim lishaem slizistoĭ obolochki polosti rta.