title: Microfibril-microvessel connections in the rabbit eye: correlative confocal and electron microscopy.
abstract: The connections between elastic tissue and microvessels (arterioles, capillaries, and venules) in the rabbit eye were examined by light and electron microscopy. In particular, confocal scanning laser microscopy of tissue stained with orcein and examined by fluorescence using a rhodamine filter was correlated with electron microscopic observations. The goal was an analysis of the way in which elastic tissue of the uvea (i.e., choroid, ciliary body, and iris) and the optic nerve of the eye connect to the microvessels in these structures. Confocal microscopy revealed these connections advantageously and showed how they link the elastic tissue meshwork in the perivascular tissue spaces with the wall of the blood vessels. Electron microscopy showed that the connections consist of bundles of 10-12 nm diameter microfilaments that insert into vascular basement membranes. These connections may contribute to the vascular response to changes in blood pressure or intraocular pressure in the eye.
authors.affiliation: Department of Ophthalmology, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, New York 10467.
authors.forename: G E
authors.initials: GE
authors.lastname: Korte
authors.forename: E E
authors.initials: EE
authors.lastname: Manche
mesh_terms: D000818:Animals; D002196:Capillaries / Q000648:ultrastructure; D002829:Choroid / Q000098:blood supply / Q000648:ultrastructure; D002924:Ciliary Body / Q000098:blood supply / Q000648:ultrastructure; D005123:Eye / Q000098:blood supply* / Q000648:ultrastructure; D007498:Iris / Q000098:blood supply / Q000648:ultrastructure; D009900:Optic Nerve / Q000098:blood supply / Q000648:ultrastructure; D011817:Rabbits