title: Apparent isolated skin relapse in acute monocytic leukemia. A case report.
abstract: A case of acute monocytic leukemia with an apparent isolated skin relapse is reported. The cutaneous involvement was associated with a morphological bone marrow remission but a cytogenetic relapse was present. Regression of the skin lesions was obtained with a protocol including daunoblastine, aracytin and thioguanine, but the patient relapsed and died a few months later without achieving another remission. The relation between cutaneous and medullary disease is discussed.
authors.affiliation: Istituto di Semeiotica Medica, Università Cattolica del Sacro Cuore, Roma, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Pagano
authors.forename: L M
authors.initials: LM
authors.lastname: Larocca
authors.forename: M
authors.initials: M
authors.lastname: Zollino
authors.forename: S
authors.initials: S
authors.lastname: Sica
authors.forename: S
authors.initials: S
authors.lastname: Storti
authors.forename: M
authors.initials: M
authors.lastname: Rotoli
authors.forename: R
authors.initials: R
authors.lastname: Marra
authors.forename: G
authors.initials: G
authors.lastname: Leone
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007948:Leukemia, Monocytic, Acute / Q000188:drug therapy / Q000473:pathology*; D012008:Recurrence; D012074:Remission Induction; D012878:Skin Neoplasms / Q000473:pathology*