Polymorphism of human CYP2D genes involved in drug metabolism: possible relationship to individual cancer risk.
Nebert
D W
DW
Department of Environmental Health, University of Cincinnati Medical Center, Ohio 45267-0056.
D000483:Alleles; D019389:Cytochrome P-450 CYP2D6; D003577:Cytochrome P-450 Enzyme System / Q000172:deficiency / Q000235:genetics* / Q000502:physiology; D005006:Ethnicity; D005796:Genes; D020022:Genetic Predisposition to Disease; D006801:Humans; D008658:Inactivation, Metabolic / Q000235:genetics*; D008175:Lung Neoplasms / Q000235:genetics; D006899:Mixed Function Oxygenases / Q000172:deficiency / Q000235:genetics* / Q000502:physiology; D009369:Neoplasms / Q000139:chemically induced / Q000208:ethnology / Q000235:genetics*; D011110:Polymorphism, Genetic; D011544:Pseudogenes; D012307:Risk Factors; D001749:Urinary Bladder Neoplasms / Q000235:genetics
D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D019389:Cytochrome P-450 CYP2D6