Cytogenetics of endometrial adenocarcinoma.
The results of karyotypic analysis of a new case of endometrial adenocarcinoma revealed in all analyzed diploid or near-diploid cells two chromosomes 1 of normal morphology and the presence of a marker or markers derived from chromosome 1. No other common chromosome marker was observed. Among a total of 25 endometrial adenocarcinoma cases reported in literature, including the case we reported, the most frequent chromosome abnormality-observed was trisomy and tetrasomy of the long arm of chromosome 1 which may represent a specific karyotypic change in at least one subtype of this tumor.
Horgas
G
G
Nuclear Medicine and Oncology Department, Dr Mladen Stojanović University Hospital, Zagreb.
Grubisić
G
G
Lokner
V
V
D000230:Adenocarcinoma / Q000235:genetics*; D000368:Aged; D002869:Chromosome Aberrations; D002878:Chromosomes, Human, Pair 1; D005260:Female; D006801:Humans; D007621:Karyotyping; D014594:Uterine Neoplasms / Q000235:genetics*