title: Immunocytochemical evidence for the site of O-methylation in rat dental pulp.
abstract: Immunocytochemical observations by light and electron microscopy of catechol-O-methyltransferase (COMT) were conducted in dental pulp by use of a specific antibody to soluble rat-liver COMT and the peroxidase-antiperoxidase technique. Immunoreactive deposits were found in macrophages. The pattern of localization suggests that COMT may function in extraneuronal inactivation of catecholamines in dental pulp.
authors.affiliation: Department of Oral Anatomy, Okayama University, Dental School, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Inoue
authors.forename: T
authors.initials: T
authors.lastname: Nishino
authors.forename: C R
authors.initials: CR
authors.lastname: Creveling
mesh_terms: D000818:Animals; D002394:Catechol O-Methyltransferase / Q000378:metabolism*; D002462:Cell Membrane / Q000648:ultrastructure; D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D003782:Dental Pulp / Q000166:cytology / Q000201:enzymology*; D007124:Immunoenzyme Techniques; D008264:Macrophages / Q000166:cytology / Q000201:enzymology; D008297:Male; D008745:Methylation; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D002394:Catechol O-Methyltransferase