[Significance of hyponatremia in patients with oropharyngeal tumors].
We observed 29 patients with hyponatremia associated with oropharyngeal carcinoma. In 19/29 the hyponatremia was attributable to a decreased effective arterial blood volume whereas in the remainder (10/29) the presence of SIADH could be demonstrated. These etiologies of hyponatremia were best differentiated by the plasma urea concentration (less than 30 mg/dl in SIADH), urate concentration (less than 4,0 mg/dl in SIADH) and creatinine concentration (less than 0,9 mg/dl in SIADH). Furthermore, SIADH patients had a spontaneous natriuresis. The mainstay of therapy in either form of hyponatremia is fluid restriction (less than 1 l/d).
Ketteler
M
M
Medizinische Universitätsklinik, Heidelberg.
Gross
P
P
Menstell
S
S
Weidauer
H
H
D002294:Carcinoma, Squamous Cell / Q000503:physiopathology*; D003404:Creatinine / Q000097:blood; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000209:etiology / Q000503:physiopathology*; D007177:Inappropriate ADH Syndrome / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009959:Oropharyngeal Neoplasms / Q000503:physiopathology*; D012964:Sodium / Q000097:blood; D014882:Water-Electrolyte Balance / Q000502:physiology*
D012964:Sodium; D003404:Creatinine
Bedeutung der Hyponatriämie bei Patienten mit oropharyngealen Tumoren.