[Erythrocyte sodium-lithium countertransporter level as a risk factor of hypertension (prospective study data)].
A 3-year prospective study was undertaken to evaluate the relation of red blood cell Na+/Li+ countertransport rates to the incidence of arterial hypertension. A total of 227 subjects (males and females aged 24-54 years)--a 20% representative sample of organized population--was followed up. The annual incidence of arterial hypertension was 4.3 among males and 2.7 among females. The baseline blood pressures and obesity in males and rates of Na+/Li+ countertransport in females were demonstrated to be factors associated with the incidence of arterial hypertension. The rate of red blood cell Na+/Li+ countertransport can be regarded as an independent biological risk factor for arterial hypertension.
Britov
A N
AN
Kobal'
A M
AM
Sapozhnikov
I I
II
Orlov
S N
SN
Pokudin
N I
NI
Grishenkov
E A
EA
D000328:Adult; D017920:Antiporters; D001794:Blood Pressure / Q000502:physiology*; D002352:Carrier Proteins / Q000097:blood*; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D012737:Sex Factors
D017920:Antiporters; D002352:Carrier Proteins; C045885:sodium-lithium countertransporter
Velichina Na+/Li+ protivotransporta éritrotsitov kak faktor riska gipertonicheskoĭ bolezni (dannye prospektivnogo issledovaniia).