title: Hemochromatosis and pyruvate kinase deficiency. Report of a case and review of the literature.
abstract: Hemochromatosis has been reported in several patients with chronic hemolytic anemia due to pyruvate kinase deficiency. We describe here a further patient with such an association and review the literature on the subject. We hypothesize that iron overload may occur in patients with pyruvate kinase deficiency who are also carriers of the hereditary hemochromatosis gene.
authors.affiliation: Department of Human Sciences, Université du Quebec, Chicoutimi, Canada.
authors.forename: M
authors.initials: M
authors.lastname: De Braekeleer
authors.forename: C
authors.initials: C
authors.lastname: St-Pierre
authors.forename: A
authors.initials: A
authors.lastname: Vigneault
authors.forename: H
authors.initials: H
authors.lastname: Simard
authors.forename: E
authors.initials: E
authors.lastname: de Medicis
mesh_terms: D000328:Adult; D000743:Anemia, Hemolytic / Q000209:etiology; D005260:Female; D006432:Hemochromatosis / Q000150:complications* / Q000235:genetics; D006801:Humans; D011770:Pyruvate Kinase / Q000172:deficiency* / Q000235:genetics
chemical_list: D011770:Pyruvate Kinase