[A case of complete remission obtained with etoposide in uterine choriocarcinoma].
A 27-year-old female was admitted to Sendai National Hospital complaining of continuous slight genital bleeding for about one and a half year after incomplete abortion. At first visit, urinary hCG was elevated to 32,000 IU/l and ultrasonography revealed a heterogeneous tumor in the uterus body. After abdominal simple total hysterectomy, the sample was diagnosed pathologically as a uterine choriocarcinoma. The patient was treated with 2 courses of MTX, but this regimen was not so effective. Because of persistent elevation of urinary hCG, 2 courses of etoposide were performed and hCG was rapidly reduced to within LH level. Etoposide (25 mg/day per os) was given to the patient for about three months since hospitalization and now complete remission has been obtained.
Kikuchi
J
J
Dept. of Obstetrics and Gynecology, Sendai National Hospital.
Sasaki
T
T
Ishibashi
K
K
Takaya
R
R
Mori
H
H
Endo
H
H
Shima
I
I
Moritsuka
T
T
Takahashi
K
K
D000284:Administration, Oral; D000328:Adult; D002822:Choriocarcinoma / Q000188:drug therapy* / Q000601:surgery; D003131:Combined Modality Therapy; D005047:Etoposide / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007044:Hysterectomy; D012074:Remission Induction; D014594:Uterine Neoplasms / Q000188:drug therapy* / Q000601:surgery
D005047:Etoposide