title: [Comparative evaluation of the effects of ethacizine and Bonnecor in the treatment of supraventricular paroxysmal tachycardia].
abstract: The efficacy of ethacizine was investigated in 46 patients, whereas that of Bonnecor++ was examined in 31 patients who suffered from frequent episodes of supraventricular paroxysmal tachycardia. After intravenous administration of ethacizine and ++Bonnecor, tachycardia was sustained in 41 (89.1%) and 14 (45.0%) cases, respectively. Their arresting effect was observed in all 17 (100%) cases of nodal tachycardia and in 19 (82.6%) cases of orthodromic tachycardia. Moreover, the effect was obtained in 3 (75.0%) cases of antidromic tachycardia and in one case of atrial ectopic tachycardia. ++Bonnecor abolished an episode of nodal tachycardia only in 3 (23.0%) patients and that of orthodromic tachycardia in 9 (56.3%). Its effect was also seen in one case of antidromic tachycardia and in one case of atrial ectopic tachycardia. ++Anti-recurrence++ effects of ethacizine and ++Bonnecor in repeated episode provocation were seen in 26 (70.5%) and 10 (32.0%) cases, respectively. Side effects occurred more frequently when ethacizine was used.
authors.forename: A I
authors.initials: AI
authors.lastname: Lukoshiavichiute
authors.forename: D A
authors.initials: DA
authors.lastname: Gedrimene
authors.forename: G
authors.initials: G
authors.lastname: Fol'kman
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D003984:Dibenzazepines / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D010640:Phenothiazines / Q000627:therapeutic use*; D013614:Tachycardia, Paroxysmal / Q000188:drug therapy*; D013617:Tachycardia, Supraventricular / Q000188:drug therapy*
chemical_list: D000889:Anti-Arrhythmia Agents; D003984:Dibenzazepines; D010640:Phenothiazines; C048166:tiracizine; C046818:ethacizine
vernacular_title: Sravnitel'naia otsenka éffektivnosti étatsizina i bonekora pri lechenii nadzheludochkovoĭ paroksizmal'noĭ takhikardii.