[The role of fibronectin in the development of fibrosis].
The structure, location, and function of fibronectin are reviewed on the basis of the data available in the literature. The contribution of fibronectin to the pathogenesis of granulomatous diseases, including pneumoconioses is shown in the paper. Formation of pulmonary fibrosis++ in pneumoconioses and its involvement of fibronectin are outlined in detail. The ways of further studies of this glycoprotein in occupational pulmonary diseases are also discussed.
Iaglov
V V
VV
Loshchilov
Iu A
IuA
Babok
A A
AA
D003094:Collagen / Q000378:metabolism*; D005353:Fibronectins / Q000378:metabolism*; D006099:Granuloma / Q000209:etiology*; D006801:Humans; D008168:Lung / Q000378:metabolism* / Q000473:pathology; D008264:Macrophages / Q000378:metabolism; D011009:Pneumoconiosis / Q000209:etiology*; D011658:Pulmonary Fibrosis / Q000209:etiology*
D005353:Fibronectins; D003094:Collagen
Rol' fibronektina v razvitii fibrozov.