The level of dietary protein affects the vitamin B-6 requirement of cats.
A depletion-repletion model was used to study the effect of the level of dietary protein on the vitamin B-6 requirement of growing kittens. Twenty kittens were given a pyridoxine-free diet for 42 d to deplete vitamin B-6 reserves. They then were divided into four groups of five kittens each. Two groups were fed diets containing 30% casein with either 1.0 (Group 30-1) or 2.0 (Group 30-2) mg pyridoxine/kg diet and two groups were fed 60% casein diets with either 1.0 (Group 60-1) or 2.0 (Group 60-2) mg pyridoxine/kg diet for 44 d. During repletion, body weight gain of kittens from Group 30-2 was higher than that of kittens from the other groups. Body weight gains of kittens from Groups 30-1 and 60-2 were higher than that of kittens from Group 60-1, but there was no difference in body weight gain between Groups 30-1 and 60-2. At 44 d of repletion, kittens from Group 60-1 generally had higher plasma concentrations of free tyrosine and cystathionine, lower plasma B-6 vitamin concentrations and a higher urinary oxalate excretion than did kittens from the other groups. These findings indicate that the vitamin B-6 requirement of growing kittens--as is true of humans, chickens and mice--is positively related to the level of protein in the diet. For a 30% casein diet, the vitamin B-6 requirement was greater than or equal to 1.0 but less than 2.0 mg pyridoxine/kg diet; for a 60% casein diet, the requirement was greater than or equal to 2.0 mg pyridoxine/kg diet.
Bai
S C
SC
Department of Physiological Sciences, School of Veterinary Medicine, University of California, Davis 95616.
Sampson
D A
DA
Morris
J G
JG
Rogers
Q R
QR
D000596:Amino Acids / Q000097:blood; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D002415:Cats / Q000254:growth & development*; D002851:Chromatography, High Pressure Liquid; D003404:Creatinine / Q000652:urine; D004044:Dietary Proteins / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D009751:Nutritional Requirements; D011736:Pyridoxine / Q000008:administration & dosage* / Q000097:blood / Q000378:metabolism
D000596:Amino Acids; D004044:Dietary Proteins; D003404:Creatinine; D011736:Pyridoxine