Identification and characterization of two new methylicosadienoic acids from Erylus formosus.
The novel fatty acids 18-methyl-5,9-icosadienoic acid [1] and 19-methyl-5,9-icosadienoic acid [2] were identified in the Caribbean sponge Erylus formosus. Other interesting fatty acids identified were the branched acids 3-methylpentadecanoic acid and 3-methylhexadecanoic acid, which are known to possess larvicidal activity. The most stable conformation of the new acid 19-methyl-5,9-icosadienoic acid is also presented as predicted by Molecular Mechanics (MM2) calculations. The sterol composition of E. formosus is also reported.
Carballeira
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Department of Chemistry, University of Puerto Rico, Rio Piedras 00931.
Negrón
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D000818:Animals; D005231:Fatty Acids, Unsaturated / Q000737:chemistry / Q000302:isolation & purification*; D008968:Molecular Conformation; D011161:Porifera / Q000032:analysis*
D005231:Fatty Acids, Unsaturated; C069237:18-methyl-5,9-eicosadienoic acid; C069236:19-methyl-5,9-eicosadienoic acid