title: Indications for penetrating keratoplasty: 1980-1988.
abstract: A retrospective analysis was undertaken of the clinical diagnoses of 1594 eyes that underwent penetrating keratoplasty performed in a private-referral corneal practice over a 9-year period, 1980-1988. The seven most common indications for surgery were keratoconus (24.0%), pseudophakic or aphakic bullous keratopathy (21.2%), corneal scarring (13.9%), Fuchs' endothelial dystrophy (12.5%), regraft (8.1%), and herpetic keratitis (5.3%). Keratoconus was the leading indication from 1980 to 1985. From 1985 to 1988, pseudophakic bullous keratopathy became the leading indication and correlates well with known complications associated with closed-loop anterior chamber lenses, which were widely used during the early 1980s. Less frequent indications for penetrating keratoplasty included the following: infectious (nonviral) keratitis (3.5%); acute or chronic ulcerative keratitis (2.7%); interstitial keratitis (1.8%); mechanical trauma (1.5%); other (non-Fuchs') corneal dystrophies (1.4%); congenital opacities (0.8%); and chemical burns (0.5%).
authors.affiliation: Department of Ophthalmology, University of Washington, Seattle.
authors.forename: T D
authors.initials: TD
authors.lastname: Lindquist
authors.forename: J S
authors.initials: JS
authors.lastname: McGlothan
authors.forename: W M
authors.initials: WM
authors.lastname: Rotkis
authors.forename: J W
authors.initials: JW
authors.lastname: Chandler
mesh_terms: D001035:Aphakia / Q000601:surgery; D003316:Corneal Diseases / Q000175:diagnosis / Q000601:surgery*; D005642:Fuchs' Endothelial Dystrophy / Q000601:surgery; D006801:Humans; D015994:Incidence; D007635:Keratitis, Dendritic / Q000601:surgery; D007640:Keratoconus / Q000601:surgery; D015948:Keratoplasty, Penetrating; D007910:Lenses, Intraocular; D011300:Preoperative Care; D012086:Reoperation; D012189:Retrospective Studies