Immune-mediated hemolytic anemia in a horse.
An 18-year-old Quarter Horse gelding was determined to have immune-mediated hemolytic anemia after detection of autoagglutination of RBC spherocytosis as well as a positive direct Coombs test result. A lack of response to treatment with corticosteroids necessiated the administration of cyclophosphamide and azathioprine. The anemia resolved after treatment with chemotherapeutic drugs.
Messer
N T
NT
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523.
Arnold
K
K
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000744:Anemia, Hemolytic, Autoimmune / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D000818:Animals; D001379:Azathioprine / Q000627:therapeutic use; D003298:Coombs Test / Q000662:veterinary; D003520:Cyclophosphamide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006384:Hemagglutination; D006734:Horse Diseases / Q000175:diagnosis* / Q000188:drug therapy; D006736:Horses; D008297:Male
D000305:Adrenal Cortex Hormones; D003520:Cyclophosphamide; D001379:Azathioprine