Intense immunoreactivity for Mn-superoxide dismutase (Mn-SOD) in cholinergic and non-cholinergic neurons in the rat basal forebrain.
The immunohistochemical localization of manganese (Mn)-superoxide dismutase (Mn-SOD) was studied in the rat basal forebrain using polyclonal antibodies to Mn-SOD. Neurons of the basal forebrain exhibit a high density of Mn-SOD immunoreactivity. Double immunostaining with a monoclonal antibody to choline acetyltransferase demonstrated that both cholinergic and non-cholinergic neurons in the basal forebrain are intensely immunoreactive for Mn-SOD.
Inagaki
S
S
Department of Anatomy, Osaka City University Medical School, Japan.
Takagi
H
H
Suzuki
K
K
Akai
F
F
Taniguchi
N
N
D000818:Animals; D002795:Choline O-Acetyltransferase / Q000276:immunology; D004591:Electrophoresis, Polyacrylamide Gel; D005455:Fluorescent Antibody Technique; D015151:Immunoblotting; D007150:Immunohistochemistry; D008297:Male; D009474:Neurons / Q000201:enzymology* / Q000276:immunology; D010275:Parasympathetic Nervous System / Q000201:enzymology* / Q000648:ultrastructure; D051381:Rats; D011919:Rats, Inbred Strains; D013482:Superoxide Dismutase / Q000276:immunology*
D013482:Superoxide Dismutase; D002795:Choline O-Acetyltransferase