Reduction of P3 latency during outcome from post-traumatic amnesia.
We studied 10 patients with post-traumatic amnesia (PTA) and normal CTscans. P3 with an oddball paradigm, several neuropsychological tests and EEG were performed the day after the trauma and several times later until full recovery. In all patients, P3 latencies at admission were above normal limits (mean + 2 SDs) and decreased progressively during recovery from PTA. The latency reductions correlated significantly with improvement of neuropsychological tests.
Onofrj
M
M
Department of Neurology, State University of Chieti, Italy.
Curatola
L
L
Malatesta
G
G
Bazzano
S
S
Colamartino
P
P
Fulgente
T
T
D000293:Adolescent; D000328:Adult; D000647:Amnesia / Q000175:diagnosis / Q000503:physiopathology*; D001143:Arousal / Q000502:physiology*; D001924:Brain Concussion / Q000175:diagnosis / Q000503:physiopathology*; D001931:Brain Mapping / Q000295:instrumentation; D002540:Cerebral Cortex / Q000503:physiopathology*; D003128:Coma / Q000503:physiopathology; D004569:Electroencephalography / Q000295:instrumentation*; D005072:Evoked Potentials, Auditory / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D015600:Glasgow Coma Scale; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011930:Reaction Time / Q000502:physiology*; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*