title: [Effectiveness of anaprilin in the treatment of glaucoma].
abstract: Effects of 1% anaprilin instillations on intraocular pressure, ocular hydro- and hemodynamics, anterior chamber depth, pupil width, ocular functions, systemic arterial pressure and pulse rate were studied in 57 patients (94 eyes) with primary open-angle glaucoma. Anaprilin has shown a manifest hypotensive effect, explained by depression of aqueous humor production. The drug did not influence the visual functions, pupil width, or anterior chamber depth. A synergic effect on intraocular pressure was observed when anaprilin was combined with pilocarpine or clopheline.
authors.forename: V N
authors.initials: VN
authors.lastname: Ermakova
authors.forename: L A
authors.initials: LA
authors.lastname: Kondé
authors.forename: N G
authors.initials: NG
authors.lastname: Davydova
authors.forename: L M
authors.initials: LM
authors.lastname: Buromskaia
authors.forename: G D
authors.initials: GD
authors.lastname: Maliuta
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003000:Clonidine / Q000008:administration & dosage / Q000494:pharmacology; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005260:Female; D005901:Glaucoma / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D010862:Pilocarpine / Q000008:administration & dosage / Q000494:pharmacology; D011433:Propranolol / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D010862:Pilocarpine; D011433:Propranolol; D003000:Clonidine
vernacular_title: Effektivnost' anaprilina v lechenii glaukomy.