title: [The prevention of allergic diseases in 174 children "at risk" for atopy].
abstract: Recent studies have demonstrated that it is possible to reduce allergic diseases in subjects "at risk" for atopy through the adoption of particular dietetic-environmental manipulations in the first few months of life. We have followed-up prospectively 174 infants, children and/or brothers of atopics, born at San Giovanni Calibita Hospital of Rome. In all cases, exclusive breast feeding for the first 6 months of life was recommended, with integration/replacement with soy milk (Isomil, Abbott), delayed weaning beyond the 6th month of life and rigorous hygienic environmental manipulation. The low prevalence of atopic disease (10%) and the absence of serious allergic manifestations in this "at risk" population confirms the advantage of such preventive programs.
authors.affiliation: Servizio Speciale di Allergologia ed Immunologia Clinica, Università di Roma La Sapienza, Italia.
authors.forename: G
authors.initials: G
authors.lastname: Bruno
authors.forename: P G
authors.initials: PG
authors.lastname: Giampietro
authors.forename: R
authors.initials: R
authors.lastname: Nisini
authors.forename: T
authors.initials: T
authors.lastname: Mancuso
authors.forename: L
authors.initials: L
authors.lastname: Businco
mesh_terms: D001942:Breast Feeding; D004198:Disease Susceptibility; D004780:Environment, Controlled; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006967:Hypersensitivity / Q000453:epidemiology / Q000517:prevention & control*; D015994:Incidence; D007225:Infant Food; D007231:Infant, Newborn; D007558:Italy / Q000453:epidemiology; D008297:Male; D015995:Prevalence; D012307:Risk Factors
vernacular_title: Prevenzione delle malattie allergiche in 174 bambini "a rischio" per atopia.