title: What is the value of methotrexate in the treatment of advanced colorectal cancer?
authors.forename: M J
authors.initials: MJ
authors.lastname: O'Connell
authors.forename: C G
authors.initials: CG
authors.lastname: Moertel
authors.forename: M A
authors.initials: MA
authors.lastname: Poon
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002277:Carcinoma / Q000188:drug therapy*; D015179:Colorectal Neoplasms / Q000188:drug therapy*; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage; D008727:Methotrexate / Q000627:therapeutic use*; D011379:Prognosis
chemical_list: D002955:Leucovorin; D005472:Fluorouracil; D008727:Methotrexate