title: [Assays of arylsulfatase activity in psychotic patients. Review of the literature and results of a study of 22 patients].
abstract: After a clinical and biological description of arylsulfatase A and metachromatic leucodystrophy, we present the results of a study of leucocyte arylsulfatase A in a population of 22 adult psychotic inpatients. The patients, clinically defined, filled the criteria of DSM III of schizophrenic disorders. All of them were treated by neuroleptics. None of these 22 patients showed a level of arylsulfatase A different from the range of 27 healthy adult controls. These results differ from those of most precedent studies of arylsulfatase A in "psychiatric populations". Some explanations of this difference are suggested. The concept of "purely psychiatric" form of adult metachromatic leucodystrophy is discussed.
authors.affiliation: Service de Psychiatrie, Hôpital Louis Mourier, Colombes.
authors.forename: M
authors.initials: M
authors.lastname: Lejoyeux
authors.forename: G
authors.initials: G
authors.lastname: Dubois
authors.forename: J C
authors.initials: JC
authors.lastname: Turpin
authors.forename: N
authors.initials: N
authors.lastname: Baumann
authors.forename: T
authors.initials: T
authors.lastname: Lempérière
mesh_terms: D000328:Adult; D000368:Aged; D001192:Arylsulfatases / Q000097:blood*; D005260:Female; D006801:Humans; D007962:Leukocytes / Q000201:enzymology*; D008297:Male; D008875:Middle Aged; D011618:Psychotic Disorders / Q000201:enzymology; D012562:Schizophrenia, Disorganized / Q000097:blood*; D012563:Schizophrenia, Paranoid / Q000097:blood*
chemical_list: D001192:Arylsulfatases
vernacular_title: Dosages de l'activité de l'arylsulfatase chez les malades psychotiques. Revue de la littérature et résultats d'une étude chez 22 patients.