title: Pyoderma gangrenosum with cutaneous T-cell lymphoma manifested as lower extremity ulcers--case reports.
abstract: Patients with extensive lower extremity ulcerations initially thought to be vascular disease were subsequently proved to have pyoderma gangrenosum and malignant lymphoma. Both patients died of sepsis; one patient exhibited hypogammaglobulinemia involving immunoglobulins IgA, IgG, and IgE; in the second patient, a polyclonal excess involving IgA and IgE was present.
authors.affiliation: Department of Surgery, Tulane University School of Medicine, New Orleans, Louisiana.
authors.forename: A
authors.initials: A
authors.lastname: Kitahama
authors.forename: P Y
authors.initials: PY
authors.lastname: Roland
authors.forename: M D
authors.initials: MD
authors.lastname: Kerstein
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000378:metabolism; D007871:Leg Ulcer / Q000209:etiology*; D016410:Lymphoma, T-Cell, Cutaneous / Q000150:complications* / Q000276:immunology; D011711:Pyoderma / Q000150:complications*; D012878:Skin Neoplasms / Q000150:complications* / Q000276:immunology
chemical_list: D007136:Immunoglobulins