Human and mouse hepatic aldehyde dehydrogenases important in the biotransformation of cyclophosphamide and the retinoids.
Sladek
N E
NE
Department of Pharmacology, University of Minnesota, Minneapolis 55455.
Dockham
P A
PA
Lee
M O
MO
D000444:Aldehyde Dehydrogenase / Q000302:isolation & purification / Q000378:metabolism*; D000818:Animals; D001711:Biotransformation; D002846:Chromatography, Affinity; D002850:Chromatography, Gel; D002852:Chromatography, Ion Exchange; D003520:Cyclophosphamide / Q000378:metabolism*; D003600:Cytosol / Q000201:enzymology; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000302:isolation & purification / Q000378:metabolism*; D007700:Kinetics; D008099:Liver / Q000201:enzymology*; D051379:Mice; D008875:Middle Aged; D008930:Mitochondria, Liver / Q000201:enzymology*; D012176:Retinoids / Q000378:metabolism*; D013379:Substrate Specificity
D007527:Isoenzymes; D012176:Retinoids; D003520:Cyclophosphamide; D000444:Aldehyde Dehydrogenase