Failure of naloxone to block the reduction in burying behaviour after ejaculation in male rats.
In the present study we analyzed whether the opiate nociceptive system participates in the reduction in burying behaviour observed after ejaculation. To that purpose the opiate antagonist naloxone (0.5, 1.0 and 2.0 mg/kg) was administered before ejaculation. The results showing that this antagonist does not interfere with the drastic reduction in burying behaviour suggest that an opiate nociceptive mechanism is not involved in this effect. Present data further support the idea that the reduction in burying behaviour is reflecting a specific reduction in anxiety.
Fernández-Guasti
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Departamento de Farmacología y Toxicología, CINVESTAV, México, D.F.
Saldívar
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D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects*; D004542:Ejaculation / Q000502:physiology*; D008297:Male; D009270:Naloxone / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains
D009270:Naloxone