Effects of low energy beta-irradiation from tritiated water on the morphology of 3T3 fibroblasts.
Cellular alterations of cultured 3T3 cells irradiated with beta-rays from tritiated water were studied by scanning and transmission electron microscopy. We observed decreased negative surface charges, vacuolization of rough endoplasmic reticulum and Golgi-complex, degeneration of mitochondria, increase of lysosomal activity and changes in distribution and amount of microfilaments in the irradiated cells, that parallelled changes in cell shape.
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Frédéric Joliot-Curie, National Research Institute for Radiobiology and Radiohygiene, Budapest, Hungary.
Kubasova
T
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Kovács
J
J
Köteles
G J
GJ
D000818:Animals; D001610:Beta Particles; D002460:Cell Line; D005347:Fibroblasts / Q000187:drug effects / Q000528:radiation effects* / Q000648:ultrastructure; D051379:Mice; D008855:Microscopy, Electron, Scanning; D014316:Tritium; D014867:Water / Q000737:chemistry
D014867:Water; D014316:Tritium