Increased risk of profound weight loss among women exposed to diethylstilbestrol in utero.
We surveyed 1711 women exposed to diethylstilbestrol in utero, and 919 women not exposed, concerning lifetime weight loss histories. The prevalence of a history of unexplained profoundly low body weight (weight less than or equal to 80% of expected weight for age, sex, and height) was 18.7 per 1000 in the exposed group compared to 3.3 per 1000 in the unexposed group; a 5.72 to 1 ratio of increased risk.
Gustavson
C R
CR
Center for Environmental Studies, Arizona State University, Tempe 85287-3211.
Gustavson
J C
JC
Noller
K L
KL
O'Brien
P C
PC
Melton
L J
LJ
Pumariega
A J
AJ
Kaufman
R H
RH
Colton
T
T
D000328:Adult; D000568:Amenorrhea / Q000139:chemically induced; D000856:Anorexia Nervosa / Q000139:chemically induced*; D004054:Diethylstilbestrol / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D012307:Risk Factors; D015431:Weight Loss / Q000187:drug effects*
D004054:Diethylstilbestrol