title: Clinical diagnosis and course of Alzheimer's disease.
abstract: Alzheimer's disease can be accurately diagnosed by clinical methods alone in about 90% of cases. The adoption of uniform diagnostic criteria and assessment procedures, such as those developed by the Consortium to Establish a Registry for Alzheimer's Disease (CERAD), will likely improve the characterization of the disease across a variety of clinical settings. In general, Alzheimer's disease is a relentlessly progressive disorder; however, it also is clinically heterogeneous. This is underscored by its diverse cognitive deficits, neurologic features, behavioral pathology, and rates of progression.
authors.affiliation: Washington University School of Medicine, St. Louis, Missouri.
authors.forename: J C
authors.initials: JC
authors.lastname: Morris
authors.forename: E H
authors.initials: EH
authors.lastname: Rubin
mesh_terms: D000544:Alzheimer Disease / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D009483:Neuropsychological Tests