title: [Cholinesterase reactivators in the combined treatment of patients with acute organophosphate insecticide poisonings].
abstract: The efficacy of different cholinesterase reactivators (alloxyme, dietixyme, dipiroxyme, isonitrosine) used as specific antidotes) was evaluated in 78 patients with acute intoxications by phosphorus-organic insecticides. The most pronounced clinical effect was obtained with use of alloxyme and dietixyme. The number of side-effects was observed during employment of dietixyme. Use of dipiroxyme with isonitrosine was less effective and was connected with a higher number of side-effects.
authors.forename: V A
authors.initials: VA
authors.lastname: Trotsevich
authors.forename: O V
authors.initials: OV
authors.lastname: Kurashov
mesh_terms: D000208:Acute Disease; D002801:Cholinesterase Reactivators / Q000627:therapeutic use*; D003131:Combined Modality Therapy / Q000379:methods; D004341:Drug Evaluation; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D009943:Organophosphorus Compounds; D011041:Poisoning / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D002801:Cholinesterase Reactivators; D007306:Insecticides; D009943:Organophosphorus Compounds
vernacular_title: Reaktivatory kholinésterazy v kompleksnom lechenii bol'nykh s ostrymi otravleniiami fosfororganicheskimi insektitsidami.