Induction of autoantibodies by human immunodeficiency virus infection and their significance.
Although many of the changes in HIV and AIDS appear to be global, on closer investigation the defects are specific and can be explained by recognized mechanisms. Despite a demonstrated concurrent polyclonal B-cell activation, studies fail to show any evidence to date of significant dysregulation of the immune system leading to serologic or clinical autoimmunity.
Solinger
A M
AM
Department of Internal Medicine, University of Cincinnati Medical Sciences Center, Ohio.
Hess
E V
EV
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology; D001323:Autoantibodies / Q000032:analysis*; D006678:HIV / Q000276:immunology*; D015483:HIV Antibodies / Q000032:analysis*; D006679:HIV Seropositivity / Q000276:immunology; D006801:Humans; D008213:Lymphocyte Activation / Q000276:immunology
D001323:Autoantibodies; D015483:HIV Antibodies