[The effect of intravenous streptokinase on selected echocardiographic and clinical parameters of patients followed up for 2 years after myocardial infarction].
54 patients (pts) aged 70 years or younger with acute transmural myocardial infarction and onset of chest pain less than 12 hours were assigned in a blind manner to streptokinase group (SK), 54--to control group, 34 pts received intravenous infusion of 1,500,000 IU of SK/hour, 14 pts--2,000,000 IU/hour, and 6 pts--3,000,000 IU/2.5 hours. Intravenous streptokinase reduced left ventricular (LV) asynergy during hospital phase, decreased LV thrombus formation, and limited myocardial necrosis size 2 years after myocardial infarction. Its effect on clinical course and prognosis after myocardial infarction was of small importance.
Poprawski
K
K
I Kliniki Kardiologii Instytutu Kardiologii AM im. K. Marcinkowskiego w Poznaniu.
Piszczek
I
I
Smukowski
T
T
Ochotny
R
R
Błaszyk
K
K
Paradowski
S
S
D000368:Aged; D004452:Echocardiography; D005500:Follow-Up Studies; D006801:Humans; D007262:Infusions, Intravenous; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011379:Prognosis; D013300:Streptokinase / Q000627:therapeutic use*
D013300:Streptokinase
Wpływ podanej dozylnie streptokinazy na wybrane parametry echokardiograficzne i kliniczne oraz losy chorych w okresie 2 lat po zawale serca.