Histological changes following submucosal Teflon injection in the bladder.
Histological examination following subureteric Teflon injection was carried out on 32 ureters and four granulomatous polyps. When the Teflon was correctly placed in the submucosa it remained circumscribed and reflux was more likely to be corrected. If the Teflon was placed more deeply it became diffuse, caused a giant cell reaction, and was less likely to correct the reflux. The granulomatous polyps may represent a reaction to leakage of Teflon from the injection site.
Brown
S
S
Department of Paediatric Surgery, Royal Belfast Hospital for Sick Children, Belfast, Northern Ireland.
Stewart
R J
RJ
O'Hara
M D
MD
Hill
C M
CM
D005549:Foreign-Body Reaction / Q000473:pathology; D006801:Humans; D007267:Injections; D011138:Polytetrafluoroethylene / Q000008:administration & dosage*; D014513:Ureter / Q000473:pathology* / Q000601:surgery; D001743:Urinary Bladder; D014718:Vesico-Ureteral Reflux / Q000473:pathology / Q000601:surgery / Q000628:therapy*
D011138:Polytetrafluoroethylene