title: Carnitine in dried blood spots: a method suitable for neonatal screening.
abstract: A method is described which enables the quantitative determination of both free and total carnitine levels in dried blood spots. This method is suitable for neonatal screening for either primary or secondary carnitine deficiency. The 95% confidence interval for free carnitine was 26-76 mumol/l (median = 44) and for total carnitine was 35-102 mumol/l (median = 60).
authors.affiliation: Division of Chemical Pathology, Royal Brisbane Hospital, Brisbane, Queensland, Australia.
authors.forename: R J
authors.initials: RJ
authors.lastname: Barns
authors.forename: F G
authors.initials: FG
authors.lastname: Bowling
authors.forename: G
authors.initials: G
authors.lastname: Brown
authors.forename: A E
authors.initials: AE
authors.lastname: Clague
authors.forename: A
authors.initials: A
authors.lastname: Thompson
mesh_terms: D002331:Carnitine / Q000097:blood* / Q000172:deficiency; D004355:Drug Stability; D006801:Humans; D007231:Infant, Newborn; D015997:Neonatal Screening / Q000379:methods* / Q000706:statistics & numerical data; D010209:Paper; D012016:Reference Values
chemical_list: D002331:Carnitine