title: [NAD- and NADP-diaphorase activity in the peripheral blood lymphocytes of patients with the B-cell variant of chronic lympholeukemia].
abstract: The authors studied the cytotoxic function, activity of NAD- and NADP-diaphorases in the peripheral blood lymphocytes in 57 patients with B-cellular variant of chronic lympholeukoses and found a significant reduction of the natural killer activity of lymphocytes, increased activity of NADP-diaphorase. Reduction of natural killer activity in patients with B-cell variant of chronic lympholeukoses did not depend on the activity of membrane diaphorases in peripheral blood lymphocytes.
authors.forename: A A
authors.initials: AA
authors.lastname: Fed'ko
authors.forename: S A
authors.initials: SA
authors.lastname: Guseva
authors.forename: L M
authors.initials: LM
authors.lastname: Tishchenko
authors.forename: L Iu
authors.initials: LIu
authors.lastname: Poliachenko
mesh_terms: D000328:Adult; D000368:Aged; D003601:Cytotoxicity Tests, Immunologic; D008058:Dihydrolipoamide Dehydrogenase / Q000097:blood*; D005260:Female; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000201:enzymology* / Q000276:immunology; D007958:Leukocyte Count; D008214:Lymphocytes / Q000201:enzymology*; D008297:Male; D008875:Middle Aged; D009252:NADPH Dehydrogenase / Q000097:blood*
chemical_list: D009252:NADPH Dehydrogenase; D008058:Dihydrolipoamide Dehydrogenase
vernacular_title: Aktivnost' NAD- i NADP-diaforaz v limfotsitakh perifericheskoĭ krovi bol'nykh B-kletochnym variantom khronicheskogo limfoleĭkoza.