Malignant osteopetrosis: hypercalcaemia after bone marrow transplantation.
A 3 year old girl presented with malignant osteopetrosis, which was treated by allogeneic bone marrow transplantation. Successful engraftment was complicated by prolonged hypercalcaemia, which was controlled by a combination of a bisphosphonate, phosphate infusions, vigorous resalination, and salmon calcitonin. She was alive and well 16 months after the transplant.
Rawlinson
P S
PS
Department of Haematology, Royal Infirmary, Glasgow.
Green
R H
RH
Coggins
A M
AM
Boyle
I T
IT
Gibson
B E
BE
D016026:Bone Marrow Transplantation; D002116:Calcitonin / Q000627:therapeutic use; D002675:Child, Preschool; D004164:Diphosphonates / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000188:drug therapy / Q000209:etiology*; D010022:Osteopetrosis / Q000601:surgery*; D000077268:Pamidronate; D010710:Phosphates / Q000627:therapeutic use; D011183:Postoperative Complications / Q000209:etiology*
D004164:Diphosphonates; D010710:Phosphates; C028815:salmon calcitonin; D002116:Calcitonin; D000077268:Pamidronate