title: Surgical management of anteriorly placed lesions at the craniocervical junction--an alternative approach.
abstract: Lesions ventral to the neuraxis at the craniocervical junction can pose a significant management problem because of their strategic location. Conventional posterolateral approaches sometimes may not permit adequate visualization of the entire base of the tumor without significant manipulation of the brain stem and spinal cord. The anterior transoral and extrapharyngeal approaches are alternate ways of exposing this region without neural retraction. However, these approaches do not provide adequate exposure of the lateral margins of the tumour, there is no control of the vertebral arteries and cranial nerves and the tumor--brain stem interface is not seen till the end of the operation. A lateral approach is described in this report which involves additional bone removal in the region of the mastoid process and the articular pillars in order to provide a true lateral perspective for the removal of these tumors. The advantages include excellent definition of the interface between the tumor and cord/brain stem without manipulation of the neuraxis, control of the ipsilateral vertrebral artery and caudal cranial nerves, ability to remove the intra- and extradural portions of the tumor in one operation and the ability to perform an immediate bony fusion if necessary. The application of this approach in the management of 9 patients with a variety of intra- and extradural lesions at the clivus and foramen magnum is discussed.
authors.affiliation: Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pennsylvania.
authors.forename: C N
authors.initials: CN
authors.lastname: Sen
authors.forename: L N
authors.initials: LN
authors.lastname: Sekhar
mesh_terms: D000293:Adolescent; D000328:Adult; D001932:Brain Neoplasms / Q000503:physiopathology / Q000601:surgery*; D002528:Cerebellar Neoplasms / Q000601:surgery; D002530:Cerebellopontine Angle / Q000601:surgery; D002817:Chordoma / Q000601:surgery; D003388:Cranial Fossa, Posterior; D003391:Cranial Nerves / Q000503:physiopathology; D005260:Female; D005500:Follow-Up Studies; D005539:Foramen Magnum; D006801:Humans; D008297:Male