Oral contraceptive-induced lupus erythematosus in a Japanese woman.
A case of oral contraceptive-induced lupus erythematosus (LE) was reported. Erythematous skin lesions were noticed on hypothenor sites of palms and acral sites of pedes. Abnormal laboratory findings included an elevated ESR, CRP and weakly positive anti-nuclear antibodies. Skin biopsy specimens from involved skin showed Clq deposits at the dermo-epidermal junction. LE-like symptoms were considered to be induced by oral contraceptives, because her symptoms disappeared after the oral contraceptives were discontinued.
Furukawa
F
F
Department of Dermatology, Faculty of Medicine, Kyoto University, Japan.
Tachibana
T
T
Imamura
S
S
Tamura
T
T
D000328:Adult; D000974:Antibodies, Antinuclear / Q000032:analysis; D003276:Contraceptives, Oral / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007564:Japan / Q000453:epidemiology; D008178:Lupus Erythematosus, Cutaneous / Q000139:chemically induced* / Q000276:immunology / Q000473:pathology
D000974:Antibodies, Antinuclear; D003276:Contraceptives, Oral; D007136:Immunoglobulins