Toxic shock syndrome toxin 1 (TSST-1) production by staphylococci isolated from goats and presence of specific antibodies to TSST-1 in serum and milk.
The ability of staphylococcal strains isolated from different anatomical sites in 133 healthy goats to produce toxic shock syndrome toxin 1 (TSST-1) and the presence of antibodies to this toxin in serum and milk were studied. The enzyme-linked immunosorbent assay method was used to detect both the toxin and the presence of antibodies. Of a total of 342 staphylococcal strains studied, 86 (25.2%) were found to produce TSST-1. Specific antibodies to TSST-1 were found in the serum of 57 (42.9%) of the animals studied and the milk of 63 (47.4%) of the animals. These results suggest that goats are frequently in contact with staphylococci that produce TSST-1, a toxin usually associated with Staphylococcus aureus strains isolated from cases of toxic shock syndrome in humans.
Valle
J
J
Unidad de Microbiologia e Inmunologia, Facultad de Veterinaria, Universidad de Extremadura, Caceres, Spain.
Vadillo
S
S
Piriz
S
S
Gomez-Lucia
E
E
D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood / Q000302:isolation & purification; D001427:Bacterial Toxins; D004768:Enterotoxins / Q000096:biosynthesis* / Q000276:immunology; D005260:Female; D006041:Goats / Q000276:immunology / Q000382:microbiology*; D008892:Milk / Q000276:immunology / Q000382:microbiology; D013045:Species Specificity; D013210:Staphylococcus / Q000378:metabolism; D013211:Staphylococcus aureus / Q000302:isolation & purification / Q000378:metabolism*; D018089:Superantigens
D000907:Antibodies, Bacterial; D001427:Bacterial Toxins; D004768:Enterotoxins; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal