title: Mitochondrial encephalomyopathy--two years follow-up by MRI.
abstract: A case of mitochondrial encephalomyopathy (MEM) followed-up by MRI for 2 1/2 y is presented. MRI showed gross, diffusely distributed white matter lesions in both hemispheres predominantly in frontal, parietal, temporal and occipital locations a marked ventriculomegaly indicative of cerebral atrophy. Except a slight increase of the cerebral atrophy there were no changes in the follow-up examinations. There are no specific MRI findings in MEM, the diagnosis is established by the synopsis of MRI, laboratory data and muscle biopsy.
authors.affiliation: Department of Radiology, University Hospital Graz, Austria.
authors.forename: K A
authors.initials: KA
authors.lastname: Hausegger
authors.forename: M M
authors.initials: MM
authors.lastname: Millner
authors.forename: F
authors.initials: F
authors.lastname: Ebner
authors.forename: F
authors.initials: F
authors.lastname: Flückiger
authors.forename: E
authors.initials: E
authors.lastname: Justich
mesh_terms: D001284:Atrophy; D001927:Brain Diseases / Q000473:pathology*; D002552:Cerebral Ventricles / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008931:Mitochondria, Muscle; D011149:Pons / Q000473:pathology