[Use of intravenous nifedipine in the treatment of cardiac insufficiency in the acute period of myocardial infarction].
The efficacy of intravenous nifedipine was examined in 42 patients with acute myocardial infarction complicated by congestive heart failure. In patients with a higher systemic arteriolar tone, its normalization caused an increase in cardiac output and tissue oxygen supply with a concomitant decrease in pressures in the lesser circulation and the right heart. In contrast, a cardiodepressive effect of the agent was shown in more than a half of the patients with para-normal values of peripheral vascular resistance. The latter is one of the determinants in selecting patients with acute heart failure to be treated with nifedipine.
Kosminskiĭ
P G
PG
Vasechkin
S S
SS
Vaniev
S B
SB
Magnitskiĭ
A V
AV
Gruzdev
A K
AK
Sidorenko
B A
BA
D000368:Aged; D002311:Cardiomyopathy, Dilated / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D004334:Drug Administration Schedule; D005260:Female; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D006801:Humans; D007260:Infusion Pumps; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications*; D009543:Nifedipine / Q000008:administration & dosage*
D009543:Nifedipine
Primenenie vnutrivennoĭ formy nifedipina v terapii serdechnoĭ nedostatochnosti u bol'nykh v ostrom perriode infarkta miokarda.