title: Imaging microbubbles and tissues using a linear focussed scanner operating at 20 MHz: possible implications for the detection of cavitation thresholds.
abstract: B-Scan images have been used as a means of detecting the onset of cavitation in tissues. New echoes appearing during simultaneous sonication with therapeutic ultrasound have often been attributed to bubble formation. In this study temperature rises up to 15 degrees C W-1 cm2 in guinea pig leg (post-mortem) were found, which would itself increase the rate of growth of gas bubbles. It is also hypothesized that a temperature dependent attenuation coefficient predicted by Bamber and Hill may, at least in part, account for new echoes appearing in tissues. Possible artefactual echoes in the B-scan images arising from acoustically induced gas bubbles in the coupling medium are also discussed.
authors.affiliation: Department of Bio-Medical Physics and Bio-Engineering, University of Aberdeen, Foresterhill, UK.
authors.forename: D J
authors.initials: DJ
authors.lastname: Watmough
authors.forename: H M
authors.initials: HM
authors.lastname: Davies
authors.forename: K M
authors.initials: KM
authors.lastname: Quan
authors.forename: R
authors.initials: R
authors.lastname: Wytch
authors.forename: A R
authors.initials: AR
authors.lastname: Williams
mesh_terms: D000818:Animals; D002645:Chickens; D005121:Extremities / Q000000981:diagnostic imaging*; D006168:Guinea Pigs; D066298:In Vitro Techniques; D013696:Temperature; D014463:Ultrasonography