[Comparative evaluation of the effects of crystalloid solutions containing sodium lactate and sodium succinate on the hemodynamic indicators in different types of hemorrhage].
The results are presented of the hemodynamics investigations under the influence of two saline infusion solutions in varying types of hemorrhage. The suggested crystalloid solution succinasol contains sodium succinate (instead of lactate that is present in lactasol) which improves energetic processes in tissues under conditions of circulatory hypoxia. The results of the study of hemodynamics parameters and animal survival rate have shown succinasol advantages as compared to the lactate-saline blood substitute in acute massive hemorrhage and reversible hemorrhagic shock.
Levin
G S
GS
Shevchenko
L I
LI
Gubaev
S A
SA
D000818:Animals; D000077324:Crystalloid Solutions; D004195:Disease Models, Animal; D005260:Female; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D006470:Hemorrhage / Q000188:drug therapy* / Q000503:physiopathology; D007552:Isotonic Solutions; D007773:Lactates / Q000008:administration & dosage*; D019344:Lactic Acid; D008297:Male; D010952:Plasma Substitutes / Q000008:administration & dosage*; D011817:Rabbits; D012996:Solutions; D013386:Succinates / Q000008:administration & dosage*; D019802:Succinic Acid
D000077324:Crystalloid Solutions; D007552:Isotonic Solutions; D007773:Lactates; D010952:Plasma Substitutes; D012996:Solutions; D013386:Succinates; D019344:Lactic Acid; D019802:Succinic Acid
Sravnitel'naia otsenka vliianiia kristalloidnykh rastvorov, soderzhashchikh laktat i suktsinat natriia, na pokazateli gemo- dinamiki pri razlichnykh vidakh krovopoteri.