title: Albino gene dosage and retinal decussation patterns in the pigmented ferret.
abstract: We have examined the retinal decussation patterns in pigmented ferrets that were either wild-type sable or heterozygous with one albino gene. Unilateral injections of horseradish peroxidase were made into the optic tract and labeled ganglion cells visualized in retinal wholemounts. In both wild-type and heterozygous ferrets, those ganglion cells in the temporal retina with the largest cell bodies projected only to the contralateral side of the brain. The total number of ipsilaterally projecting ganglion cells did not differ with the genotype of the animal. The numbers ranged from 5471-6759 cells. Unlike the cat, there is no difference in retinal decussation patterns in wild-type sable ferrets and heterozygous ferrets carrying one albino gene.
authors.affiliation: University Laboratory of Physiology, Oxford, U.K.
authors.forename: I D
authors.initials: ID
authors.lastname: Thompson
authors.forename: G
authors.initials: G
authors.lastname: Jeffery
authors.forename: J E
authors.initials: JE
authors.lastname: Morgan
authors.forename: G
authors.initials: G
authors.lastname: Baker
mesh_terms: D000417:Albinism / Q000235:genetics*; D000818:Animals; D001369:Axons; D002452:Cell Count; D005289:Ferrets; D006579:Heterozygote; D010857:Pigment Epithelium of Eye / Q000033:anatomy & histology; D012165:Retinal Ganglion Cells / Q000166:cytology*; D013477:Superior Colliculi / Q000033:anatomy & histology; D014795:Visual Pathways