title: Use of orbital floor steroids in the management of patients with uniocular non-necrotising scleritis.
abstract: Most cases of non-necrotising scleritis can be successfully treated with non-steroidal anti-inflammatory drugs. If these are ineffective, then high-dose systemic corticosteroids, with all their attendant side-effects, are usually required. We have used orbital floor injections of depot steroid in the management of nine patients with non-necrotising scleritis in an attempt to avoid the use of systemic steroids, or to allow the dose of steroids to be reduced while maintaining disease control. A temporary reduction in inflammation was achieved in all cases, which allowed the use of systemic steroids to be avoided altogether in two patients and delayed in the others. Non-steroidal anti-inflammatory drugs and systemic corticosteroids remain the mainstay of treatment for non-necrotising scleritis, but orbital floor injections may be a useful adjunct in certain cases.
authors.affiliation: Moorfields Eye Hospital, London.
authors.forename: K N
authors.initials: KN
authors.lastname: Hakin
authors.forename: J
authors.initials: J
authors.lastname: Ham
authors.forename: S L
authors.initials: SL
authors.lastname: Lightman
mesh_terms: D000328:Adult; D000368:Aged; D003692:Delayed-Action Preparations; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D009915:Orbit; D011239:Prednisolone / Q000008:administration & dosage* / Q000627:therapeutic use; D015423:Scleritis / Q000188:drug therapy*
chemical_list: D003692:Delayed-Action Preparations; D011239:Prednisolone