title: Pyoderma gangrenosum associated with systemic lupus erythematosus: response to pulse steroid therapy.
abstract: Pyoderma gangrenosum in a 35-year-old woman with long-standing systemic lupus erythematosus was treated with pulse steroid therapy. Significant improvement in the ulceration and control of the lupus erythematosus occurred. The unusual association of these disorders is reviewed, and the efficacy of pulse therapy in the treatment of refractory cases of pyoderma gangrenosum is discussed.
authors.affiliation: Department of Dermatology, Curry Cabral Hospital, Lisbon, Portugal.
authors.forename: G M
authors.initials: GM
authors.lastname: Pinto
authors.forename: M A
authors.initials: MA
authors.lastname: Cabeças
authors.forename: M
authors.initials: M
authors.lastname: Riscado
authors.forename: H
authors.initials: H
authors.lastname: Gonçalves
mesh_terms: D000328:Adult; D005260:Female; D005734:Gangrene; D006801:Humans; D007871:Leg Ulcer / Q000150:complications* / Q000188:drug therapy; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy; D008776:Methylprednisolone Hemisuccinate / Q000008:administration & dosage / Q000627:therapeutic use*; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use; D011711:Pyoderma / Q000150:complications* / Q000188:drug therapy
chemical_list: D008776:Methylprednisolone Hemisuccinate; D011241:Prednisone