Kinetics of drug action in disease states. XL. Effect of the dialyzable component(s) of uremic blood on theophylline neurotoxicity in rats.
Hoffman
A
A
Department of Pharmaceutics, School of Pharmacy, State University of New York, Buffalo 14260.
Levy
G
G
D058186:Acute Kidney Injury / Q000097:blood; D000818:Animals; D002490:Central Nervous System / Q000187:drug effects*; D003404:Creatinine / Q000097:blood; D007668:Kidney / Q000187:drug effects / Q000502:physiology; D008297:Male; D051381:Rats; D011917:Rats, Inbred Lew; D011919:Rats, Inbred Strains; D006435:Renal Dialysis / Q000379:methods; D012640:Seizures / Q000139:chemically induced*; D013806:Theophylline / Q000493:pharmacokinetics / Q000633:toxicity*; D014508:Urea / Q000097:blood; D014511:Uremia / Q000097:blood*
D014508:Urea; D003404:Creatinine; D013806:Theophylline