Serum reactivity to other indoor ficus plants in patients with allergy to weeping fig (Ficus benjamina).
Ornamental plants have long been used for indoor decoration. An example is the india rubber tree (Ficus elastica). With the increased popularity of green plants, both in private homes and public premises, small-leaf species, such as weeping fig or Ficus benjamina (Fb), have become widely used. Exposure to dust from Fb may cause sensitization and allergic airway symptoms, which among occupationally exposed plant keepers occur both in atopics and non-atopics. The serum reactivity to sap extracts from Fb and seven other indoor plants of the genus Ficus were investigated with RAST and a RAST inhibition technique, using sera from 12 atopic subjects and 12 plant keepers, sensitized to Fb. The allergenic similarity between the different extracts was found to be extensive. The specific IgE antibodies with the highest concentrations in serum were those against Fb and its variegate form, "star light", with decreasing values for the other species, especially those with larger leaves. The binding of IgE antibodies to the other Ficus RAST discs could be completely inhibited by extract of Fb. These reactions were probably due to cross-reactivity. Sensitization is believed to occur by inhalation of allergen-enriched dust, emanating from the leaves of the plants. The high allergenic potency of the species with many small leaves may be due to their large total leaf area.
Axelsson
I G
IG
Department of Clinical Immunology, Karolinska Hospital, Stockholm, Sweden.
Johansson
S G
SG
Larsson
P H
PH
Zetterström
O
O
D000485:Allergens; D000906:Antibodies / Q000032:analysis; D003429:Cross Reactions; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000097:blood* / Q000276:immunology; D007073:Immunoglobulin E / Q000032:analysis; D010944:Plants / Q000276:immunology*; D011852:Radioallergosorbent Test
D000485:Allergens; D000906:Antibodies; D007073:Immunoglobulin E