Studies on the venom components of the long-glanded coral snake, Maticora bivirgata.
The venom of the Asian long-glanded coral snake, Maticora bivirgata, was fractionated into five fractions, S1-S5, by passing through a Sephadex G-50 column. Fraction S2 contains two phospholipases A2, PLA2 I and PLA2 II, fraction S3 contains four cytotoxin homologues, maticotoxins A, C, D1 and D2, and fractions S4 and S5 contain a large amount (about 1 mg/specimen) of adenosine accompanied with smaller amounts of inosine and guanosine. The amino-terminal amino acid sequences of PLA2, I, PLA2 II and maticotoxin A suggest that Maticora bivirgata is closely related to Bungarinae, especially to genera Hemachatus and Naja.
Takasaki
C
C
Department of Chemistry, Faculty of Science, Tohoku University, Sendai, Japan.
Yoshida
H
H
Shimazu
T
T
Teruuchi
T
T
Toriba
M
M
Tamiya
N
N
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001667:Binding, Competitive; D001681:Biological Assay; D002850:Chromatography, Gel; D002852:Chromatography, Ion Exchange; D002855:Chromatography, Thin Layer; D004546:Elapid Venoms / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D007928:Lethal Dose 50; D008297:Male; D013058:Mass Spectrometry; D051379:Mice; D008969:Molecular Sequence Data; D010741:Phospholipases A / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D054467:Phospholipases A2; D012911:Snakes; D013056:Spectrophotometry, Ultraviolet
D000596:Amino Acids; D004546:Elapid Venoms; D010741:Phospholipases A; D054467:Phospholipases A2