Epikeratoplasty for keratoglobus associated with blue sclera.
Patients with keratoglobus and blue sclera as part of a generalized connective tissue disorder are at a high risk of developing corneal perforations either spontaneously or after mild trauma. Six patients (6 eyes) between the ages of 2 and 16 years of age (mean, 7.5 years) with keratoglobus, blue sclera, hypermobile joints, and consanguineous parents were treated by epikeratoplasty, using commercially prepared 12.5-mm lenticules. Surgery was performed for tectonic support and/or visual improvement and was successful in five of six patients with a follow-up period of 11 to 27 months (mean, 21 months). One lenticule was removed because the epithelium did not heal. Peripheral interface opacities occurred in three patients.
Cameron
J A
JA
King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
Cotter
J B
JB
Risco
J M
JM
Alvarez
H
H
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003240:Connective Tissue Diseases / Q000473:pathology / Q000601:surgery; D003316:Corneal Diseases / Q000473:pathology / Q000601:surgery*; D016039:Corneal Transplantation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011379:Prognosis; D015422:Scleral Diseases / Q000473:pathology / Q000601:surgery*; D013577:Syndrome; D014792:Visual Acuity