title: Stomach cancer: a study of 117 consecutive resected cases and results of R2-R3 gastrectomy.
abstract: In a consecutive series of 175 patients with gastric carcinoma, 66.8% underwent gastric resection: 74 total gastrectomies with R3 lymphadenectomy and 43 distal subtotal gastrectomies with R2 lymphadenectomy were performed. 73% (86 cases) of resective procedures proved to be "absolute curative" according to Japanese criteria (JRSGC). Nodal involvement was present in 62 out of 117 resected patients (52.9%): 29.9% N1, 9.4% N2, 13.6% N3; a significant relationship (p = 0.012) between depth of invasion of the gastric wall and lymph node metastases was revealed. The hospital mortality after R2-R3 gastrectomy was 4.2%, major surgical complications occurred in 6.8% of cases. The actuarial 5-year survival after curative resection was 59%. The results suggest that extended lymphadenectomy (R2-R3 gastrectomy) is justified in the surgical treatment of gastric cancer; this procedure can be safely performed and permits "absolute curative" resections in a remarkable percentage of cases.
authors.affiliation: Istituto di Patologia Chirurgica, Università Cattolica del Sacro Cuore, Roma, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Crucitti
authors.forename: G B
authors.initials: GB
authors.lastname: Doglietto
authors.forename: R
authors.initials: R
authors.lastname: Bellantone
authors.forename: F
authors.initials: F
authors.lastname: Pacelli
authors.forename: V
authors.initials: V
authors.lastname: Perri
authors.forename: O
authors.initials: O
authors.lastname: Tommasini
mesh_terms: D000206:Actuarial Analysis; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005069:Evaluation Studies as Topic; D005260:Female; D005743:Gastrectomy / Q000379:methods*; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*