title: Preliminary evidence for bacterial endotoxin therapeutics of paraquat lethality in mice.
abstract: In mice treated with endotoxin (LPS) extracted from Escherichia coli (1 mg/kg, i.p.), 3 hr after paraquat (70 mg/kg, i.p.) a delay in the appearance of deaths and a decrease in their number in 10-day cumulative mortality were observed in comparison to those injected with saline after paraquat.
authors.affiliation: Department of Pharmacology and Toxicology, Cancer Research Institute, Tohoku College of Pharmacy, Sendai, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Ishikawa
authors.forename: Y
authors.initials: Y
authors.lastname: Takayanagi
authors.forename: K
authors.initials: K
authors.lastname: Sasaki
mesh_terms: D000818:Animals; D004731:Endotoxins / Q000627:therapeutic use*; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D010269:Paraquat / Q000633:toxicity*
chemical_list: D004731:Endotoxins; C044101:endotoxin, Escherichia coli; D010269:Paraquat