Acute intermittent porphyria with atypical neuropathy.
The patient we have described had lower extremity numbness, paresthesias, constipation, urinary retention, and sexual dysfunction. Laboratory evaluation confirmed a diagnosis of acute intermittent porphyria (AIP). Vitamin B6 and glucose therapy initiated resolution of symptoms. The sensory neuropathy described here is unusual, and we believe sexual dysfunction is a previously unreported manifestation of AIP.
Goren
M B
MB
Department of Medicine, Fairfax Hospital, Va.
Chen
C
C
D000328:Adult; D005947:Glucose / Q000627:therapeutic use; D009477:Hereditary Sensory and Autonomic Neuropathies / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D008297:Male; D011164:Porphyrias / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D011736:Pyridoxine / Q000627:therapeutic use
D005947:Glucose; D011736:Pyridoxine