Effects of acute, graded compression on spinal nerve root function and structure. An experimental study of the pig cauda equina.
A well-controlled experimental model for analysis of compression-induced functional changes of the porcine cauda equina is presented. The model allows for electrophysiologic investigation of a variety of neurophysiologic changes induced by nerve root deformation. At an acute pressure threshold of 50-75 mm Hg, changes in both afferent and efferent conduction are induced. With higher compression pressure, a differential recovery in afferent and efferent conduction is seen.
Rydevik
B L
BL
Department of Orthopaedics, University of Göteborg, Sweden.
Pedowitz
R A
RA
Hargens
A R
AR
Swenson
M R
MR
Myers
R R
RR
Garfin
S R
SR
D000200:Action Potentials / Q000502:physiology; D000344:Afferent Pathways / Q000502:physiology; D000818:Animals; D002420:Cauda Equina / Q000473:pathology / Q000503:physiopathology*; D004525:Efferent Pathways / Q000502:physiology; D004576:Electromyography; D009408:Nerve Compression Syndromes / Q000473:pathology / Q000503:physiopathology*; D009431:Neural Conduction / Q000502:physiology; D011312:Pressure; D011984:Sensory Receptor Cells / Q000502:physiology; D013552:Swine