MR of progressive neurodegenerative change in treated Menkes' kinky hair disease.
MR examinations of a male child with Menkes' kinky hair disease, a genetic disorder of copper metabolism, at four months and 30 months, document the progression of neurodegenerative changes despite parenteral copper therapy. These changes include severe cortical and cerebellar atrophy, deranged cerebral vasculature, and subdural fluid collection.
Johnsen
D E
DE
Department of Radiology Geisinger Medical Center Danville, Pennsylvania.
Coleman
L
L
Poe
L
L
D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D007706:Menkes Kinky Hair Syndrome / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed