[Immunological assay of substances of blood and vascular bed origin, and their future].
Recently in the clinical laboratories, many highly sensitive immunological measurements are performed using such techniques as radioimmunoassay, enzyme immunoassay, fluoroimmunoassay, and chemiluminescence immunoassay. However, the metabolic clearance rate of a very small amount of substance in the circulatory blood may participate intimately in its inactivation and/or trapping in a single passage through a certain organ. The difficulty of immunological assays for very small amounts of biologically active substances in blood and the possibility of developing an easier assay method are discussed.
Michibayashi
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Department of Laboratory Diagnosis, Sapporo Medical College.
D000818:Animals; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D011453:Prostaglandins / Q000097:blood*; D013928:Thromboxane A2 / Q000097:blood; D013963:Thyroid Hormones / Q000097:blood*; D001613:beta 2-Microglobulin / Q000032:analysis*
D011453:Prostaglandins; D013963:Thyroid Hormones; D001613:beta 2-Microglobulin; D013928:Thromboxane A2