Necrotizing fasciitis and nonsteroidal anti-inflammatory drugs.
We have presented a case of fulminant necrotizing fasciitis that occurred after excessive NSAID intake with granulocytopenia. This case parallels those previously reported as outlined in the above discussion. We concur with previous investigators who have concluded that NSAIDs should be used with caution in patients with phlebitis or apparently benign inflammatory cutaneous lesions.
Smith
R J
RJ
Department of Internal Medicine, East Tennessee State University James H. Quillen College of Medicine, Johnson City 37614.
Berk
S L
SL
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D005208:Fasciitis / Q000139:chemically induced* / Q000382:microbiology / Q000401:mortality; D006801:Humans; D008297:Male; D009336:Necrosis; D011183:Postoperative Complications; D013290:Streptococcal Infections / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000302:isolation & purification
D000894:Anti-Inflammatory Agents, Non-Steroidal