title: Possible allergic reactions to cyclopentolate hydrochloride: case reports with literature review of uses and adverse reactions.
abstract: Cyclopentolate has been widely used as a cycloplegic and mydriatic agent for over 30 years. It has gained widespread use as the cycloplegic drug of first choice for most children over the age of 1 year and allows many optometrists and ophthalmologists to carry out quick, successful cycloplegic refractions with few complications. During this time very few side-effects have been reported with the most commonly used 1% solution. This paper outlines two cases in which a possible allergic-type reaction occurred shortly after the instillation of 1% cyclopentolate hydrochloride in 'Minims' form (Smith and Nephew). This article also reviews the uses and side-effects of cyclopentolate and aims to warn practitioners about the possibility of such reactions, ways of avoiding their occurrence and suitable measures to take should they occur.
authors.affiliation: Institute of Optometry, London, UK.
authors.forename: L W
authors.initials: LW
authors.lastname: Jones
authors.forename: D T
authors.initials: DT
authors.lastname: Hodes
mesh_terms: D002648:Child; D002675:Child, Preschool; D002924:Ciliary Body / Q000187:drug effects; D003519:Cyclopentolate / Q000009:adverse effects* / Q000494:pharmacology; D004342:Drug Hypersensitivity / Q000209:etiology*; D005128:Eye Diseases / Q000175:diagnosis; D005260:Female; D006801:Humans; D009184:Mydriatics / Q000009:adverse effects*; D009883:Ophthalmic Solutions; D011680:Pupil / Q000187:drug effects
chemical_list: D009184:Mydriatics; D009883:Ophthalmic Solutions; D003519:Cyclopentolate