Diabetes insipidus due to pituitary metastasis from bladder cancer.
We report a 41-year-old man with bladder cancer who developed polyuria following successful treatment of hypercalcemia and who was found to have a transitional cell carcinoma within the pituitary gland at autopsy. He also had widespread bone metastases. Although primary urogenital cancers rarely metastasize to the pituitary, the patient's clinical course led us to suspect metastatic disease from the bladder cancer. Metastasis to the pituitary gland is more common than generally thought and should be considered in patients with advanced cancer who develop polyuria and polydipsia.
Kawamura
J
J
Department of Urology, Mie University School of Medicine, Tsu, Japan.
Tsukamoto
K
K
Yamakawa
K
K
Tazima
K
K
Tochigi
H
H
D000328:Adult; D001859:Bone Neoplasms / Q000556:secondary; D002295:Carcinoma, Transitional Cell / Q000150:complications / Q000473:pathology / Q000556:secondary*; D003919:Diabetes Insipidus / Q000209:etiology*; D006801:Humans; D008297:Male; D010911:Pituitary Neoplasms / Q000150:complications / Q000473:pathology / Q000556:secondary*; D011859:Radiography; D001749:Urinary Bladder Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*