title: Streptococcus pyogenes vulvovaginitis in children in Nottingham.
abstract: Isolates of Streptococcus pyogenes from vaginal swabs of children with vulvovaginitis received at Nottingham Public Health Laboratory during 1986-9 were studied. A total of 159 isolates was made during the 4 years, increasing from 17 in 1986 to 64 in 1989 and accounting for 11% of all vaginal swabs received from children. The numbers of throat swabs yielding S. pyogenes also showed an increase from 974 in 1986 to 1519 in 1989. A winter peak of isolates was noted for both vaginal swabs and throat swabs. A total of 98 strains from vaginal swabs were serotyped: 22 different types were identified, 61% of which were the common types M4, M6, R28 and M12. Erythromycin sensitivity was done on 89 strains; 84% were highly sensitive (MIC less than 0.03 mg/l). There are no other reports of such large numbers in the literature; the reason for seeing this increase in Nottingham is unclear.
authors.affiliation: Department of Microbiology, University Hospital, Queen's Medical Centre, Nottingham.
authors.forename: F E
authors.initials: FE
authors.lastname: Donald
authors.forename: R C
authors.initials: RC
authors.lastname: Slack
authors.forename: G
authors.initials: G
authors.lastname: Colman
mesh_terms: D002648:Child; D002675:Child, Preschool; D004739:England / Q000453:epidemiology; D004917:Erythromycin / Q000494:pharmacology; D005260:Female; D006801:Humans; D007223:Infant; D010614:Pharynx / Q000382:microbiology; D012621:Seasons; D012703:Serotyping; D013290:Streptococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013297:Streptococcus pyogenes / Q000145:classification / Q000187:drug effects / Q000302:isolation & purification*; D014621:Vagina / Q000382:microbiology; D014848:Vulvovaginitis / Q000453:epidemiology* / Q000382:microbiology
chemical_list: D004917:Erythromycin