The X chromosome of marsupials shares a highly conserved region with eutherians.
Ten genes, located on the long arm of the human X chromosome, were mapped in several marsupial species by somatic cell analysis and in situ hybridization. All were located on the X chromosome in each species. We conclude that the long arm of the human X chromosome represents a highly conserved region that formed part of the X chromosome in a therian ancestor 120-150 million years ago, before the mammalian infraclasses diverged.
Spencer
J A
JA
Department of Genetics and Human Variation, Bundoora, Victoria, Australia.
Watson
J M
JM
Graves
J A
JA
D000818:Animals; D005075:Biological Evolution; D015139:Blotting, Southern; D002460:Cell Line; D002874:Chromosome Mapping; D006801:Humans; D006822:Hybrid Cells; D008394:Marsupialia / Q000235:genetics*; D009693:Nucleic Acid Hybridization; D012377:Rodentia; D014960:X Chromosome