title: The effect of 0.1% Indomethacin eyedrops on cataract surgery.
abstract: Topical use of Indomethacin was documented to prevent surgically induced miosis, and it reduced postoperative inflammatory response. We collected 26 consecutive cataract eyes. Seventeen eyes in the study group received topical 0.1% Indomethacin eyedrops from one day before surgery until two weeks after surgery, in addition to the routine medications. Nine eyes belonging to the control group received the routine medications only. The parameters of our study included the measurement of the pupil diameters in surgery, the central corneal thickness, the intraocular pressure, and the anterior chamber reaction before and after surgery. The results revealed that topical use of 0.1% Indomethacin eyedrops could prevent intraoperative miosis and reduce postoperative corneal edema and anterior chamber reaction, but it did not show much influence on intraocular pressure.
authors.affiliation: Department of Ophthalmology, Jen-Ai Municipal Hospital, Taipei, Taiwan, Republic of China.
authors.forename: S W
authors.initials: SW
authors.lastname: Liou
authors.forename: R J
authors.initials: RJ
authors.lastname: Yen
mesh_terms: D002387:Cataract Extraction; D006801:Humans; D007213:Indomethacin / Q000627:therapeutic use*; D007429:Intraocular Pressure; D007431:Intraoperative Complications / Q000517:prevention & control*; D015877:Miosis / Q000517:prevention & control*; D009798:Ocular Hypertension / Q000517:prevention & control; D009883:Ophthalmic Solutions; D011183:Postoperative Complications / Q000517:prevention & control; D011292:Premedication
chemical_list: D009883:Ophthalmic Solutions; D007213:Indomethacin