Role of aldehyde dehydrogenase (ALDH) in the detoxication of cyclophosphamide (CP) in rat embryos.
Mirkes
P E
PE
Department of Pediatrics, University of Washington, Seattle 98195.
Ellison
A
A
Little
S A
SA
D000444:Aldehyde Dehydrogenase / Q000378:metabolism*; D000818:Animals; D001711:Biotransformation; D003520:Cyclophosphamide / Q000031:analogs & derivatives / Q000378:metabolism* / Q000493:pharmacokinetics / Q000633:toxicity; D004351:Drug Resistance; D004622:Embryo, Mammalian / Q000187:drug effects / Q000378:metabolism*; D006321:Heart / Q000196:embryology; D008658:Inactivation, Metabolic; D007939:Leukemia L1210 / Q000378:metabolism; D051379:Mice; D009206:Myocardium / Q000201:enzymology; D009924:Organ Culture Techniques; D051381:Rats; D013379:Substrate Specificity
D003520:Cyclophosphamide; D000444:Aldehyde Dehydrogenase; C011272:perfosfamide