title: [Renin secreting tumor and severe hypertension. Apropos of a new case].
abstract: A renin-secreting tumour has been observed in a 32-year-old female with severe hypertension known for 17 years. The excision of the tumour lead to the complete normalisation of the blood pressure. Histological examination showed that the tumour was benign, contained secretion granules at different stages of maturation, and derived from the juxta-glomerular apparatus. After reviewing the 40 cases previously reported in the literature we discuss the clinical presentation of this type of tumour and the approach to their diagnosis.
authors.affiliation: Unité Néphrologie-Hémodialyse, Centre Hospitalier d'Annecy.
authors.forename: F
authors.initials: F
authors.lastname: Ducret
authors.forename: P
authors.initials: P
authors.lastname: Pointet
authors.forename: C
authors.initials: C
authors.lastname: Lambert
authors.forename: J
authors.initials: J
authors.lastname: Pin
authors.forename: M
authors.initials: M
authors.lastname: Baret
authors.forename: J M
authors.initials: JM
authors.lastname: Botta
authors.forename: M
authors.initials: M
authors.lastname: Mutin
authors.forename: S
authors.initials: S
authors.lastname: Colon
authors.forename: M
authors.initials: M
authors.lastname: Vincent
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D006977:Hypertension, Renal / Q000209:etiology*; D007124:Immunoenzyme Techniques; D007606:Juxtaglomerular Apparatus; D007668:Kidney / Q000473:pathology; D007680:Kidney Neoplasms / Q000150:complications / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology / Q000601:surgery; D008854:Microscopy, Electron; D012083:Renin / Q000378:metabolism*; D014057:Tomography, X-Ray Computed
chemical_list: D012083:Renin
vernacular_title: Tumeur à rénine et hypertension artérielle sévère. A propos d'un nouveau cas.