pH-dependent fusion of tick-borne encephalitis virus with artificial membranes.
pH-dependent fusion of TBE virus with artificial membranes was effective at slightly acidic pH with maximum at 6.4. The influence of various changes in E protein conformation on fusion process was studied.
Vorovitch
M F
MF
Institute of Poliomyelitis and Viral Encephalitides, U.S.S.R. Academy of Medical Sciences, Moscow.
Timofeev
A V
AV
Atanadze
S N
SN
Tugizov
S M
SM
Kushch
A A
AA
Elbert
L B
LB
D000818:Animals; D000911:Antibodies, Monoclonal; D002478:Cells, Cultured; D004669:Encephalitis Viruses, Tick-Borne / Q000502:physiology*; D006863:Hydrogen-Ion Concentration; D008567:Membranes, Artificial; D011487:Protein Conformation; D014759:Viral Envelope Proteins / Q000378:metabolism; D014760:Viral Fusion Proteins / Q000378:metabolism
D000911:Antibodies, Monoclonal; D008567:Membranes, Artificial; D014759:Viral Envelope Proteins; D014760:Viral Fusion Proteins; C065696:glycoprotein E, Flavivirus