[Effects of androgens and gestagens on uterine myoma].
One hundred and sixty resected intramural myomas have been examined in 78 women with an intact menstrual cycle: 61 nodes from 31 patients of 37 to 57 years without a history of hormonal treatment, 52 nodes from 26 patients of 39 to 57 years with a history of androgen treatment and 47 nodes from 21 women of 30 to 50 years with a history of gestagen treatment. The histologic, histochemical, morphometric and biochemical studies showed that androgen and gestagen treatment stabilized and diminished the myomas, promoted secondary changes in the nodes and caused a statistically significant activation of sclerotic processes. Therapeutic effects of androgens were superior to those of gestagens.
Pashkova
V S
VS
Erokhin
Iu A
IuA
D000328:Adult; D000970:Antineoplastic Agents; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000188:drug therapy* / Q000473:pathology; D008777:Methyltestosterone / Q000627:therapeutic use*; D008875:Middle Aged; D011374:Progesterone / Q000627:therapeutic use*; D012598:Sclerosis; D013739:Testosterone / Q000627:therapeutic use*; D014594:Uterine Neoplasms / Q000188:drug therapy* / Q000473:pathology
D000970:Antineoplastic Agents; D013739:Testosterone; D011374:Progesterone; D008777:Methyltestosterone
Vliianie androgenov i gestagenov na miomu matki.