The growing teratoma syndrome.
A 26-year-old man presented with multiple pulmonary nodules and a left testicular mass. Combination chemotherapy for a malignant, mixed germ cell testicular tumor resulted in shrinkage of the pulmonary nodules and normalization of the tumor markers (beta-HCG, LDH and AFP). Subsequent surgical excision performed for enlargement of the pulmonary nodules revealed mature teratomas, diagnostic of the GTS.
Basheda
S G
SG
Department of Pulmonary Disease, Cleveland Clinic Foundation.
Gephardt
G
G
Meeker
D P
DP
D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D003884:Dermoid Cyst / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D008175:Lung Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D008297:Male; D011859:Radiography; D013736:Testicular Neoplasms / Q000473:pathology
D014408:Biomarkers, Tumor