Delayed onset movement disorders as a complication of central pontine myelinolysis.
This report describes a case of central pontine myelinolysis occurring after a rapid correction of profound hyponatremia. Delayed-onset generalized dystonia and choreoathetosis then appeared. A small pontine myelinolysis was demonstrated by magnetic resonance images, but striatal myelinolysis could not be established. Aspects of movement disorders associated with the osmotic demyelination syndrome are briefly reviewed and discussed.
Tison
F X
FX
Department of Neurology, Hôpital du Haut Lévêque, Pessac, France.
Ferrer
X
X
Julien
J
J
D001264:Athetosis / Q000139:chemically induced* / Q000473:pathology; D002819:Chorea / Q000139:chemically induced* / Q000473:pathology; D003711:Demyelinating Diseases / Q000139:chemically induced* / Q000473:pathology; D004421:Dystonia / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007008:Hypokalemia / Q000188:drug therapy*; D007010:Hyponatremia / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009460:Neurologic Examination; D011149:Pons / Q000187:drug effects* / Q000473:pathology; D011189:Potassium Chloride / Q000008:administration & dosage / Q000009:adverse effects*; D012462:Saline Solution, Hypertonic / Q000008:administration & dosage / Q000009:adverse effects*
D012462:Saline Solution, Hypertonic; D011189:Potassium Chloride