[Stevens-Johnson syndrome associated with Mycoplasma pneumoniae infection in an adult].
A case of Stevens-Johnson syndrome caused by Mycoplasma pneumoniae in a 34-year-old woman is presented. At first, she was admitted for treatment of pneumonia with cefuzonam. She was discharged in good health twelve days after admission. However, three days after discharge, she was admitted again with fever, erythematous lesions, oral ulcerations and exudative conjunctivitis. Because M. pneumoniae infection was confirmed by the presence of an elevated IHA titer, a clinical diagnosis of Stevens-Johnson syndrome associated with M. pneumoniae infection was made. Also, Mycoplasma CF antigen-lymphocyte stimulation test (LST) gave positive results, while the cefuzonam-LST was negative. Treatment with methylprednisolone and minocycline was initiated. Resolution of lesion was evident only after thirty days and then steroid therapy was discontinued. This association has rarely been reported in adults. M. pneumoniae infection should be considered in cases of Stevens-Johnson syndrome in adults with pneumonia.
Iwata
M
M
Department of Internal Medicine, Kariya General Hospital, Japan.
Tano
M
M
Ikuta
N
N
Inagaki
T
T
Suzuki
S
S
Kondo
M
M
Naito
Y
Y
Matsumoto
S
S
D000328:Adult; D000942:Antigens, Bacterial / Q000276:immunology; D005260:Female; D006801:Humans; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000276:immunology; D009174:Mycoplasma / Q000276:immunology; D011019:Pneumonia, Mycoplasma / Q000150:complications* / Q000276:immunology; D013262:Stevens-Johnson Syndrome / Q000209:etiology* / Q000276:immunology
D000942:Antigens, Bacterial