title: Pentagastrin and histamine in the regulation of gastric mucosal blood flow.
abstract: The current state of our knowledge concerning mediator(s) of the increase in gastric mucosal blood flow that occurs during pentagastrin- and histamine-stimulated acid secretion is reviewed. Evidence for a role for adenosine, prostaglandin, and histamine is presented and discussed. The dose relationship between the acid-stimulatory and the vascular permeability effects of histamine is also presented.
authors.affiliation: Medical Service, VA Medical Center West Los Angeles, CA 90073.
authors.forename: P H
authors.initials: PH
authors.lastname: Guth
mesh_terms: D000241:Adenosine / Q000502:physiology; D000818:Animals; D005744:Gastric Acid / Q000378:metabolism; D005753:Gastric Mucosa / Q000098:blood supply* / Q000378:metabolism; D006632:Histamine / Q000502:physiology*; D006801:Humans; D010418:Pentagastrin / Q000494:pharmacology*; D011453:Prostaglandins / Q000502:physiology; D012039:Regional Blood Flow / Q000502:physiology
chemical_list: D011453:Prostaglandins; D006632:Histamine; D010418:Pentagastrin; D000241:Adenosine