Re-examination of Rattus norvegicus as an animal model for Aeromonas-associated enteritis in man.
We have developed an oral feeding model for Aeromonas hydrophila enteritis using Rattus norvegicus with clindamycin pretreatment. All animals in the clindamycin group developed a self-limited, loose stool by day four of feeding. Intestinal examination revealed evidence of enteritis. Moreover, antibiotic usage may be a predisposing risk factor to infection.
Haberberger
R L
RL
Department of Research Sciences, U.S. Naval Medical Research Unit No. Three, Cairo, Egypt.
Yonushonis
W P
WP
Daise
R L
RL
Mikhail
I A
IA
Ishak
E A
EA
D000333:Aeromonas; D000818:Animals; D001424:Bacterial Infections / Q000382:microbiology*; D002981:Clindamycin / Q000008:administration & dosage; D004195:Disease Models, Animal; D004751:Enteritis / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D002981:Clindamycin