title: Periumbilical pseudoxanthoma elasticum with systemic manifestations.
abstract: We have reviewed the typical clinical manifestations of pseudoxanthoma elasticum and presented the case of a patient with involvement of the skin, eyes, and cardiovascular system. We suggest that patients with periumbilical lesions that might indicate pseudoxanthoma elasticum have, at minimum, a full physical examination with emphasis on the cardiovascular system and a complete ophthalmologic evaluation.
authors.affiliation: Department of Dermatology, Medical College of Georgia, Augusta 30912-2900.
authors.forename: B G
authors.initials: BG
authors.lastname: Goldstein
authors.forename: J L
authors.initials: JL
authors.lastname: Lesher
mesh_terms: D005260:Female; D006801:Humans; D008875:Middle Aged; D011561:Pseudoxanthoma Elasticum / Q000175:diagnosis / Q000473:pathology*; D014472:Umbilicus