[Effectiveness of anaprilin in the treatment of glaucoma].
Effects of 1% anaprilin instillations on intraocular pressure, ocular hydro- and hemodynamics, anterior chamber depth, pupil width, ocular functions, systemic arterial pressure and pulse rate were studied in 57 patients (94 eyes) with primary open-angle glaucoma. Anaprilin has shown a manifest hypotensive effect, explained by depression of aqueous humor production. The drug did not influence the visual functions, pupil width, or anterior chamber depth. A synergic effect on intraocular pressure was observed when anaprilin was combined with pilocarpine or clopheline.
Ermakova
V N
VN
Kondé
L A
LA
Davydova
N G
NG
Buromskaia
L M
LM
Maliuta
G D
GD
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003000:Clonidine / Q000008:administration & dosage / Q000494:pharmacology; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005260:Female; D005901:Glaucoma / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D010862:Pilocarpine / Q000008:administration & dosage / Q000494:pharmacology; D011433:Propranolol / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*
D010862:Pilocarpine; D011433:Propranolol; D003000:Clonidine
Effektivnost' anaprilina v lechenii glaukomy.