title: Autofluorescence of normal and malignant bronchial tissue.
abstract: In vivo autofluorescence spectra were obtained in 5 patients with carcinoma in situ, 26 patients with invasive tumors, and 1 patient with severe dysplasia. Significant spectral differences were observed between pre-cancerous, cancerous, and normal bronchial tissues. This difference may afford a method to image and/or detect early lung cancer by using tissue autofluorescence alone.
authors.affiliation: Cancer Imaging Section, British Columbia Cancer Agency, Vancouver, Canada.
authors.forename: J
authors.initials: J
authors.lastname: Hung
authors.forename: S
authors.initials: S
authors.lastname: Lam
authors.forename: J C
authors.initials: JC
authors.lastname: LeRiche
authors.forename: B
authors.initials: B
authors.lastname: Palcic
mesh_terms: D001980:Bronchi / Q000473:pathology; D002278:Carcinoma in Situ / Q000175:diagnosis; D002283:Carcinoma, Bronchogenic / Q000175:diagnosis* / Q000473:pathology; D005453:Fluorescence; D005470:Fluorometry; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology; D013050:Spectrometry, Fluorescence