title: Malignant transformation of a Hürthle cell tumor: case report and survey of the literature.
abstract: Hürthle cell carcinoma is a relatively uncommon type of well-differentiated thyroid carcinoma. Its diagnosis has been controversial due to the difficulty in separating Hürthle cell adenoma from Hürthle cell carcinoma, thus the term Hürthle cell tumor is often used to describe both lesions. The present case of anaplastic giant-cell carcinoma in an 81-yr-old woman arose in a Hürthle cell tumor. This case illustrates the propensity of Hürthle cell tumor to undergo "malignant transformation" and argues for a more aggressive approach to such tumors.
authors.affiliation: Nuclear Medicine Service, VA Medical Center, Long Beach, CA 90822.
authors.forename: R J
authors.initials: RJ
authors.lastname: McDonald
authors.forename: S Y
authors.initials: SY
authors.lastname: Wu
authors.forename: J L
authors.initials: JL
authors.lastname: Jensen
authors.forename: L N
authors.initials: LN
authors.lastname: Parker
authors.forename: K P
authors.initials: KP
authors.lastname: Lyons
authors.forename: E M
authors.initials: EM
authors.lastname: Moran
authors.forename: W H
authors.initials: WH
authors.lastname: Blahd
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging / Q000473:pathology*; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D011877:Radionuclide Imaging; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*
chemical_list: D007457:Iodine Radioisotopes