title: Coexisting depression and anxiety: special diagnostic and treatment issues.
abstract: Anxiety and depression often coexist in the clinical setting. Using panic disorder as an example, the author presents an overview of the prevalence, familial aspects, and long- and short-term outcomes of such comorbid disorders. Evidence regarding the diagnostic category of mixed anxiety-depression is also reviewed. On the basis of the limited available data, the author advances possible treatment strategies for treating patients with comorbid depression and anxiety disorders. Combined pharmacologic therapies may be indicated to optimize treatment for some patients. The review underscores the need for treatment studies in patients with depression and coexisting anxiety.
authors.affiliation: Institute of Psychiatry, Medical University of South Carolina, Charleston 29425.
authors.forename: R B
authors.initials: RB
authors.lastname: Lydiard
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use; D001008:Anxiety Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D015897:Comorbidity; D003663:Decision Trees; D003866:Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D004359:Drug Therapy, Combination; D006801:Humans; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology; D010200:Panic; D010698:Phobic Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology
chemical_list: D000928:Antidepressive Agents