title: Decreased renal clearance of sodium in cystic fibrosis.
abstract: In 10 patients with cystic fibrosis (CF) and 10 controls of similar age quantitative segmental handling of sodium was estimated by lithium clearance. In the CF group, there was a tendency for an increased glomerular filtration rate (GFR) and increased absolute proximal sodium reabsorption. The fractional distal sodium reabsorption was significantly (p = 0.015) increased and sodium clearance was significantly (p less than 0.01) decreased in CF.
authors.affiliation: Department of Nephrology, Karolinska Institute, Huddinge University Hospital, Sweden.
authors.forename: P
authors.initials: P
authors.lastname: Stenvinkel
authors.forename: L
authors.initials: L
authors.lastname: Hjelte
authors.forename: G
authors.initials: G
authors.lastname: Alván
authors.forename: A
authors.initials: A
authors.lastname: Hedman
authors.forename: E
authors.initials: E
authors.lastname: Hultman
authors.forename: B
authors.initials: B
authors.lastname: Strandvik
mesh_terms: D000328:Adult; D003550:Cystic Fibrosis / Q000378:metabolism*; D005260:Female; D005919:Glomerular Filtration Rate / Q000502:physiology; D006801:Humans; D007668:Kidney / Q000378:metabolism*; D008094:Lithium / Q000378:metabolism; D008297:Male; D012964:Sodium / Q000378:metabolism*
chemical_list: D008094:Lithium; D012964:Sodium