title: [Use of intravenous nifedipine in the treatment of cardiac insufficiency in the acute period of myocardial infarction].
abstract: The efficacy of intravenous nifedipine was examined in 42 patients with acute myocardial infarction complicated by congestive heart failure. In patients with a higher systemic arteriolar tone, its normalization caused an increase in cardiac output and tissue oxygen supply with a concomitant decrease in pressures in the lesser circulation and the right heart. In contrast, a cardiodepressive effect of the agent was shown in more than a half of the patients with para-normal values of peripheral vascular resistance. The latter is one of the determinants in selecting patients with acute heart failure to be treated with nifedipine.
authors.forename: P G
authors.initials: PG
authors.lastname: Kosminskiĭ
authors.forename: S S
authors.initials: SS
authors.lastname: Vasechkin
authors.forename: S B
authors.initials: SB
authors.lastname: Vaniev
authors.forename: A V
authors.initials: AV
authors.lastname: Magnitskiĭ
authors.forename: A K
authors.initials: AK
authors.lastname: Gruzdev
authors.forename: B A
authors.initials: BA
authors.lastname: Sidorenko
mesh_terms: D000368:Aged; D002311:Cardiomyopathy, Dilated / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D004334:Drug Administration Schedule; D005260:Female; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D006801:Humans; D007260:Infusion Pumps; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications*; D009543:Nifedipine / Q000008:administration & dosage*
chemical_list: D009543:Nifedipine
vernacular_title: Primenenie vnutrivennoĭ formy nifedipina v terapii serdechnoĭ nedostatochnosti u bol'nykh v ostrom perriode infarkta miokarda.