Risk factors for transient ischemic attacks in middle-age. A population-based case-control study.
A case-control study was based on "unselected" transient ischemic attacks (TIAs) in a middle-aged Italian population. The identified cases included 52 prevalent and 25 incident TIAs. There was an incidence rate ratio (female/male) of 1.8 for definite cases. Comparison with the whole population for medical history of hypertension, diabetes and heart attack showed age/sex-adjusted odds ratios of 4.3, 2.1, 7.9 for incident cases. The results were similar when a more detailed investigation of risk factors was performed with all the cases and a random sample of the controls. Moreover, female sex had an odds ratio for incident cases of 3.3 (95% confidence interval 1.0-11.3) after adjustment for age and presence of all the main risk factors. The presence of at least one cardiopathy showed an odds ratio of 8.3 for incident cases (95% confidence interval 2.4-28.4).
Fratiglioni
L
L
Department of Neurological & Psychiatric Sciences, University of Florence, Italy.
Inzitari
D
D
Arfaioli
C
C
Nencini
P
P
Ginanneschi
A
A
Pracucci
G
G
Zuppiroli
A
A
Italiani
G
G
Amaducci
L
L
D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D015994:Incidence; D002546:Ischemic Attack, Transient / Q000453:epidemiology* / Q000209:etiology; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D015995:Prevalence; D012044:Regression Analysis; D012307:Risk Factors; D011795:Surveys and Questionnaires