[Modifications in erythrocyte elongation in blood samples of test subjects following gallopamil administration].
In 12 blood samples of healthy non-smokers younger than 40 years the erythrocytes-elongation was studied after Gallopamil-incubation, to obtain data for a possible rheological effect of this substance. For incubation dosages of 20, 50 and 100 micrograms/ml were used. After incubation with 50 and 100 micrograms/ml the elongation index of red blood cells increased in a significant manner. The results show, that Gallopamil does not only have a effect for vasodilatation but also for hemorheological parameters.
Költringer
P
P
Krankenhauses der Barmherzigen Brüder, Graz-Eggenberg.
Langsteger
W
W
Lind
P
P
Klima
G
G
Reisecker
F
F
Eber
O
O
D000328:Adult; D004305:Dose-Response Relationship, Drug; D004907:Erythrocyte Deformability / Q000187:drug effects*; D005260:Female; D005711:Gallopamil / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques
D005711:Gallopamil
Veränderungen der Erythrozytenelongation unter Gallopamil in Blutproben von gesunden Versuchspersonen.