title: [Amoebic keratitis caused by Acanthamoeba sp. May HSV1 infection play a role?].
abstract: Many cases of human keratitis with Acanthamoeba sp. have a pseudo-herpetic appearance. The authors therefore evaluated the importance of co-infection with this virus in the onset of amoebic cornean lesions. After herpetic and amoebic co-infection rabbits showed severe cornean lesions, the viral aspect of cornea received a specific treatment. The amoebic co-infection progressed unchecked with severe lesions until day 37 p.i., in which trophozoites and cysts were numerous. The possible favourising role of HSV1 and Acanthamoeba sp. co-infection may exist in humans, just as it certainly exists in the rabbit.
authors.affiliation: Laboratoire de Parasitologie, UFR de Médecine, Brest.
authors.forename: E
authors.initials: E
authors.lastname: Paniagua-Crespo
authors.forename: A
authors.initials: A
authors.lastname: Tsouria-Belaid
authors.forename: C
authors.initials: C
authors.lastname: Bellon
authors.forename: J L
authors.initials: JL
authors.lastname: Jacquemin
authors.forename: A M
authors.initials: AM
authors.lastname: Simitzis-Le Flohic
mesh_terms: D015823:Acanthamoeba Keratitis / Q000150:complications* / Q000175:diagnosis; D000818:Animals; D003315:Cornea / Q000473:pathology*; D003937:Diagnosis, Differential; D004195:Disease Models, Animal; D006561:Herpes Simplex / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D007165:Immunosuppression Therapy; D011817:Rabbits; D013997:Time Factors
vernacular_title: Kératite amibienne à Acanthamoeba sp. L'infection par HSV1 aurait-elle un rôle?