title: [A case of fulminant psittacosis showing Chlamydia in TBLB specimens].
abstract: A 55-year-old female was admitted to our hospital because of high fever, nonproductive cough and dyspnea. Initially she had been treated with cephem antibiotics by a local doctor. However, acute respiratory failure due to severe pneumonia developed. The partial pressure of oxygen in arterial blood was 55.5 Torr. Her chest X-ray revealed wide-spread infiltrates with air bronchograms throughout the entire left lung, and pleural effusions were also present in the chest CT scan. Because the patient had a history of the contact with birds, we suspected psittacosis and administered Minocycline immediately. As a result, her clinical condition improved and the abnormal shadow on the chest X-ray film improved markedly in three days. Because the serum titer of a complement fixation test against Chlamydia rose to 1:512, we made the diagnosis of psittacosis. In addition, femoral muscle pain, and a high level of serum GOT, GPT, CK, Aldolase and Myoglobin indicated hepatitis and myositis. In the lung tissue specimens obtained by TBLB performed on the 10th hospital day, slight interstitial pneumonia and intracellular inclusion bodies were found by light microscopy and Chlamydial agents were found electron microscopically.
authors.affiliation: Department of Respiratory Disease, Gifu City Hospital, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Tanaka
authors.forename: K
authors.initials: K
authors.lastname: Nakahara
authors.forename: H
authors.initials: H
authors.lastname: Mimoto
authors.forename: R
authors.initials: R
authors.lastname: Tomida
authors.forename: T
authors.initials: T
authors.lastname: Sawa
authors.forename: N
authors.initials: N
authors.lastname: Yamamoto
authors.forename: S
authors.initials: S
authors.lastname: Ooshima
authors.forename: K
authors.initials: K
authors.lastname: Gotoh
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis; D001706:Biopsy; D002691:Chlamydophila psittaci / Q000276:immunology / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D007181:Inclusion Bodies, Viral / Q000648:ultrastructure; D008168:Lung / Q000382:microbiology* / Q000648:ultrastructure; D008875:Middle Aged; D009956:Psittacosis / Q000382:microbiology* / Q000473:pathology
chemical_list: D000914:Antibodies, Viral