[Effectiveness of infection prevention with latamoxef in vaginal hysterectomy. A prospective study].
A prospective clinical trial was designed to examine the influence of a single-dose prophylaxis with 2 g Latamoxef on postoperative infectious morbidity in women undergoing vaginal hysterectomy. 91 vaginal hysterectomies with latamoxef prophylaxis were compared with a similar group of 99 patients without prophylaxis. Patients in the latamoxef group had significantly less postoperative infectious morbidity (23.1%) than those in the non prophylaxis group (45.1%). Prophylactic latamoxef reduced postoperative additional antibiotic therapy in the prophylaxis group significantly. The postoperative infectious morbidity (urinary tract infections, pelvic infections, febrile morbidity) was significantly reduced by a single-dose prophylaxis with 2 g Latamoxef.
Queck
M
M
Städtische Frauenklinik, Wiesbaden, Bundesrepublik Deutschland.
Hitschold
T
T
Berle
P
P
D000328:Adult; D005260:Female; D006801:Humans; D007045:Hysterectomy, Vaginal; D007275:Injections, Intravenous; D009070:Moxalactam / Q000008:administration & dosage*; D010538:Peritonitis / Q000517:prevention & control; D011292:Premedication; D011446:Prospective Studies; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000517:prevention & control*; D014552:Urinary Tract Infections / Q000517:prevention & control
D009070:Moxalactam
Zur Wirksamkeit der Infektionsprophylaxe mit Latamoxef bei vaginalen Hysterektomien. Eine prospektive Studie.