Effects of feeding endophyte-infected fescue hay on portal and hepatic nutrient flux in steers.
Six Holstein steers (313 +/- 10 kg BW) surgically fitted with hepatic portal, mesenteric venous, mesenteric arterial, and hepatic venous catheters were used in a replicated crossover design experiment to evaluate the feeding of Acremonium coenophialum-infected fescue hay on portal-drained visceral and hepatic nutrient metabolism. Only four steers had functional hepatic catheters. Infected (INF) and endophyte-free (EF) fescue hays were harvested on the same day in May, at the soft dough stage of maturity, from a similar location in southeast Kansas. The hay was chopped through a 2.5-cm screen and fed in 12 portions daily. Intake was limited to 5.2 kg of DM/d to equalize consumption. Each experimental period lasted 21 d. Dietary CP concentration was greater for INF than for EF (9.9 vs 8.6%); however, apparent digestibilities of DM (52.6%) and N (37%) were not different. Ruminal total VFA concentrations and molar proportions were not different with the exception of butyrate, which was increased (P less than .10) for steers when they were fed INF. Feeding of INF increased (P less than .05) arterial beta-hydroxybutyrate concentration and decreased (P less than .10) arterial butyrate concentration. Steers fed EF showed a greater (P less than .05) portal-arterial concentration difference for acetate and an increased (P less than .05) net portal flux of acetate (500 vs 620 mmol/h). No differences in net flux were noted for any of the other VFA, glucose, lactate, urea N, insulin, glucagon, or prolactin.(ABSTRACT TRUNCATED AT 250 WORDS)
Harmon
D L
DL
Dept. of Anim. Sci. and Ind., Kansas State University, Manhattan 66506.
Gross
K L
KL
Kreikemeier
K K
KK
Coffey
K P
KP
Avery
T B
TB
Klindt
J
J
D000164:Acremonium; D000821:Animal Feed; D000818:Animals; D002417:Cattle / Q000378:metabolism*; D004734:Energy Metabolism; D005232:Fatty Acids, Volatile / Q000378:metabolism; D005516:Food Microbiology; D008099:Liver / Q000378:metabolism*; D008297:Male; D010101:Oxygen Consumption; D006109:Poaceae / Q000382:microbiology*; D011168:Portal System / Q000378:metabolism*; D012039:Regional Blood Flow
D005232:Fatty Acids, Volatile