title: Primary vesicoureteric reflux: treatment with subureteric injection of Polytef paste.
abstract: A series of 34 children with 40 primary refluxing ureters were treated endoscopically with a subureteric injection of polytetrafluoroethylene paste (Polytef). The amount injected ranged between 0.1 and 0.8 ml (mean 0.3). A single injection cured the reflux in 26 ureters (65%) and the grade of reflux improved in a further 9 ureters. Seven ureters required a second injection and reflux was cured in 6 of these. The overall cure rate was therefore 80% after the second injection. There was one complication due to self-limiting ureteric obstruction following injection. The procedure is quick, easy to perform and effective. We have some reservations about the long-term efficiency and safety of subureteric Polytef injection in children.
authors.affiliation: Wessex Regional Centre for Paediatric Surgery, Southampton General Hospital.
authors.forename: N
authors.initials: N
authors.lastname: Davies
authors.forename: J D
authors.initials: JD
authors.lastname: Atwell
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D005465:Fluorocarbon Polymers / Q000008:administration & dosage* / Q000009:adverse effects; D006099:Granuloma / Q000209:etiology / Q000473:pathology; D006801:Humans; D007223:Infant; D007267:Injections; D008297:Male; D011859:Radiography; D014463:Ultrasonography; D014513:Ureter / Q000000981:diagnostic imaging; D001743:Urinary Bladder / Q000000981:diagnostic imaging; D014718:Vesico-Ureteral Reflux / Q000000981:diagnostic imaging / Q000628:therapy*
chemical_list: D005465:Fluorocarbon Polymers; C010946:polytetrafluoroethane