Atypical lipoleiomyoma of the uterus.
A case of uterine atypical lipoleiomyoma in a 55-year-old obese woman is described. Histologically it was composed of atypical smooth muscle tissue and adipose tissue, as proved by immunohistochemical staining and ultrastructural study. Moreover, these studies revealed a transition from tumor smooth muscle cells to lipocytes. The features of this tumor suggest that at least some lipoleiomyomas result from lipomatous metaplasia of leiomyoma. Lipoleiomyoma is a rare lesion of the uterus, and the present tumor with an atypical leiomyomatous appearance is the first reported case of its kind. A review of previous case reports, together with the condition of this patient, revealed that patients with lipoleiomyoma are often overweight and menopausal, and have a high incidence of gallbladder disease.
Lin
M
M
Second Department of Pathology, Medical School, Osaka University, Japan.
Hanai
J
J
D003893:Desmin / Q000378:metabolism; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007889:Leiomyoma / Q000378:metabolism / Q000473:pathology*; D008875:Middle Aged; D009211:Myoglobin / Q000378:metabolism; D009418:S100 Proteins / Q000378:metabolism; D014594:Uterine Neoplasms / Q000378:metabolism / Q000473:pathology*; D014746:Vimentin / Q000378:metabolism
D003893:Desmin; D009211:Myoglobin; D009418:S100 Proteins; D014746:Vimentin