Role of glucocorticoids in the regulation of bone marrow hemopoiesis in stress reaction.
We have studied the role played by glucocorticoids in the regulation of bone marrow hemopoiesis in stress reaction. The effector influence of the adrenal cortex hormones on the committed precursor cells of erythro-granulo-monocytopoiesis mediated through the T-cell system has been confirmed. Glucocorticosteroids initiate homing of the T-cell regulators of myelopoiesis of the Lyt-1+ phenotype from the lymphoid organs into the bone marrow.
Dygai
A M
AM
Research Institute of Pharmacology, USSR Academy of Medical Sciences, Tomsk.
Shakhov
V P
VP
Mikhlenko
A V
AV
Goldberg
E D
ED
D000818:Animals; D000950:Antigens, Ly / Q000276:immunology; D001853:Bone Marrow / Q000503:physiopathology*; D005938:Glucocorticoids / Q000276:immunology / Q000502:physiology*; D006410:Hematopoiesis / Q000502:physiology*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D013315:Stress, Psychological / Q000503:physiopathology*; D013601:T-Lymphocytes / Q000276:immunology / Q000502:physiology
D000950:Antigens, Ly; D005938:Glucocorticoids