Susceptibility of anaerobic bacteria to BAY v 3522.
The activity of BAY v 3522 against 340 strains of anaerobic bacteria was determined by an agar dilution method. Its activity was compared with those of amoxicillin, amoxicillin-clavulanate, cefaclor, cefadroxil, cefoxitin, cefuroxime, cephalexin, clindamycin, doxycycline, and metronidazole. BAY v 3522, amoxicillin-clavulanate, cefoxitin, clindamycin, and metronidazole were the most active agents tested. On the basis of these results, BAY v 3522 appears to have an antibacterial activity that warrants further investigation in clinical trials.
Nord
C E
CE
Department of Microbiology, Huddinge University Hospital, Stockholm, Sweden.
Rylander
M
M
Norrby
S R
SR
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001421:Bacteria, Anaerobic / Q000187:drug effects*; D052160:Benzothiazoles; D002511:Cephalosporins / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests
D000900:Anti-Bacterial Agents; D052160:Benzothiazoles; D002511:Cephalosporins; C064738:Bay v 3522