title: [A case of increased 123I-IMP uptake in adenocarcinoma of the lung].
abstract: It has been reported that delayed 123I-IMP lung scintigraphy shows a defect corresponding to the tumor with increased accumulation around the tumor, and that an increased accumulation is associated with atelectasis and inflammation. We presented a case of increased uptake of 123I-IMP in lung cancer. None of the other reported case of increased uptake in lung cancer, to our knowledge, occurred. A 55-year-old man had a 6 cm mass in the lower lobe of the right lung. Cytologic examination with a small curette diagnosed the case as an adenocarcinoma. The 123I-IMP scintigraphy was performed 24 hours after intravenous injection of 111 MBq of 123I-IMP. The 123I-IMP SPECT lung images showed an area of increased 123I-IMP concentration corresponding to the tumor mass. The patient's subsequent course was characterized by massive pleural effusion caused by extensive invasion to the pleura despite chemotherapy. He died about 2 months after the 123I-IMP scintigraphy. The right lung removed at necropsy confirmed that the area of high 123I-IMP concentration corresponded to the mass, which proved a poorly differentiated adenocarcinoma. One should note that there is an unusual case with high 123I-IMP uptake in lung cancer.
authors.affiliation: Department of Radiology, Hyogo Medical Center for Adults.
authors.forename: T
authors.initials: T
authors.lastname: Suematsu
authors.forename: S
authors.initials: S
authors.lastname: Yoshida
authors.forename: H
authors.initials: H
authors.lastname: Yamamoto
authors.forename: T
authors.initials: T
authors.lastname: Maruta
authors.forename: K
authors.initials: K
authors.lastname: Ogawa
authors.forename: E
authors.initials: E
authors.lastname: Komoto
authors.forename: M
authors.initials: M
authors.lastname: Horio
authors.forename: I
authors.initials: I
authors.lastname: Narabayashi
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging*; D000662:Amphetamines; D006801:Humans; D007457:Iodine Radioisotopes; D020367:Iofetamine; D008175:Lung Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging
chemical_list: D000662:Amphetamines; D007457:Iodine Radioisotopes; D020367:Iofetamine