title: [The action of befol and its derivatives on monoamine oxidase of different origins].
abstract: The effect on deamination of serotonine, dopamine, tiramine and 2-phenylamine of benzamide derivatives befol, moclobemide and LIS-641 was studied. Befol and moclobemide are inhibitors of serotonine deaminating activity of MAO. The different sensitivity of this activity to the effect of the benzamide derivatives in beef or rat brain and human placenta was noted. The inhibition was more distinct in tissue homogenate than in corresponding mitochondrial fractions.
authors.forename: O A
authors.initials: OA
authors.lastname: Gol'dina
authors.forename: T A
authors.initials: TA
authors.lastname: Moskvitina
authors.forename: E M
authors.initials: EM
authors.lastname: Gankina
authors.forename: A Z
authors.initials: AZ
authors.lastname: Kirkel'
authors.forename: N S
authors.initials: NS
authors.lastname: Kamyshanskaia
authors.forename: K I
authors.initials: KI
authors.lastname: Lopatina
authors.forename: T V
authors.initials: TV
authors.lastname: Sokolova
authors.forename: V A
authors.initials: VA
authors.lastname: Zagorevskiĭ
authors.forename: A V
authors.initials: AV
authors.lastname: Val'dman
authors.forename: V Z
authors.initials: VZ
authors.lastname: Gorkin
mesh_terms: D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001549:Benzamides / Q000494:pharmacology*; D001792:Blood Platelets / Q000187:drug effects / Q000201:enzymology; D001921:Brain / Q000187:drug effects / Q000201:enzymology; D002417:Cattle; D005260:Female; D006801:Humans; D008928:Mitochondria / Q000187:drug effects / Q000201:enzymology; D020912:Moclobemide; D008995:Monoamine Oxidase / Q000187:drug effects* / Q000378:metabolism; D009025:Morpholines / Q000494:pharmacology*; D010920:Placenta / Q000187:drug effects / Q000201:enzymology; D051381:Rats
chemical_list: D000928:Antidepressive Agents; D001549:Benzamides; D009025:Morpholines; C059049:befol; D008995:Monoamine Oxidase; D020912:Moclobemide
vernacular_title: Deĭstvie befola i ego proizvodnykh na monoaminoksidazu razlichnogo proiskhozhdeniia.