[Use of group-specific contaminants A and B in albumin preparations produced from the donor, placental and abortion blood].
Assay of group-specific blood substances (GSBS) A and B was conducted in 21 series of an albumin preparation produced from donors' blood serum, in 11 series of placental and in 5 series of "Postab" albumin. GSBS content was estimated by a comparative use of poly- and monoclonal antibodies prepared in this country. More than 80% of the preparations from donors' blood serum did not contain GSBS A and B. In the preparations obtained from placental and postabortion blood the mean levels of GSBS significantly fluctuated, and with the use of poly- and monoclonal antibodies in comprised 8.3-9.1 micrograms/ml GSBS A and 16.7-42.8 micrograms/ml GSBS B, respectively. Administration to recipients of albumin preparations contaminated with GSBS may produce an immunomodulating side effect.
Migunov
V N
VN
Prokorova
N I
NI
Pozina
I M
IM
Anan'ev
V A
VA
Liakhova
T D
TD
Dubrovskaia
S G
SG
Frolova
S P
SP
Shutilina
L V
LV
D000017:ABO Blood-Group System; D000022:Abortion, Spontaneous / Q000097:blood; D001782:Blood Donors; D001787:Blood Group Incompatibility / Q000097:blood / Q000517:prevention & control*; D005260:Female; D005312:Fetal Blood; D006801:Humans; D010920:Placenta; D011247:Pregnancy; D012015:Reference Standards; D012709:Serum Albumin / Q000032:analysis / Q000592:standards / Q000627:therapeutic use*; D014586:USSR
D000017:ABO Blood-Group System; D012709:Serum Albumin
Ispol'zovanie gruppospetsificheskikh kontaminantov A i B v preparatakh al'bumina, izgotovlennykh iz syvorotok donorskoĭ, platsentarnoĭ i abortnoĭ krovi.