The recognition of self-antigens and autoimmune disease.
Recent studies have increased our understanding of the nature of autoimmune recognition and of the identity of autoantigens, at least in model systems. Knowledge of the autoantigens and the process of recognition is suggesting new therapies for autoimmune disease.
Smith
S C
SC
Department of Pathology, Washington University School of Medicine, St Louis, Missouri 63110.
Allen
P M
PM
D000818:Animals; D001323:Autoantibodies / Q000276:immunology; D001324:Autoantigens / Q000276:immunology*; D001327:Autoimmune Diseases / Q000276:immunology*; D015551:Autoimmunity; D001402:B-Lymphocytes / Q000276:immunology; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology; D004681:Encephalomyelitis, Autoimmune, Experimental / Q000276:immunology; D006801:Humans; D009103:Multiple Sclerosis / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
D001323:Autoantibodies; D001324:Autoantigens