title: Core body temperature in patients with seasonal affective disorder and normal controls in summer and winter.
abstract: The rationale for phototherapy in seasonal affective disorder (SAD) was originally based on the notion that SAD patients were light deprived during the wintertime and needed more light. We previously found normal temperature profiles of untreated SAD patients during the winter, and that phototherapy significantly enhanced the amplitude of the circadian temperature profile in SAD patients during the winter (Rosenthal et al 1990). We hypothesized that summer would act similarly on the temperature rhythm of these patients. In this study we examined the temperature data from SAD patients and normal controls during the summer and compared it to the results of our previous study. We found identical profiles for SAD patients and normal controls during the summer and that summer significantly lowered the overall temperature profiles of both groups and did not alter the amplitudes. These results raise questions about the validity of the current theories of the mechanism of light therapy.
authors.affiliation: Clinical Psychobiology Branch, NIMH, NIH, Bethesda, MD 20892.
authors.forename: A A
authors.initials: AA
authors.lastname: Levendosky
authors.forename: J R
authors.initials: JR
authors.lastname: Josep-Vanderpool
authors.forename: T
authors.initials: T
authors.lastname: Hardin
authors.forename: E
authors.initials: E
authors.lastname: Sorek
authors.forename: N E
authors.initials: NE
authors.lastname: Rosenthal
mesh_terms: D000328:Adult; D001143:Arousal / Q000502:physiology*; D001833:Body Temperature Regulation / Q000502:physiology*; D002940:Circadian Rhythm / Q000502:physiology*; D003866:Depressive Disorder / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D004734:Energy Metabolism / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012621:Seasons; D013972:Thyrotropin / Q000097:blood
chemical_list: D013972:Thyrotropin