On the prevalence of transcriptional regions in human genomic DNA.
The dinucleotide sequences TpA and CpG are differentially expressed in transcribed vs. non-transcribed portions of the human genome (Beutler et al., 1989, Proc. natn. Acad. Sci. U.S.A. 86, 192-196). This fact is exploited here to estimate the total number of transcriptional regions in human genomic DNA.
Koziol
J A
JA
Department of Molecular and Experimental Medicine, Research Institute of Scripps Clinic, La Jolla, California 92037.
D004247:DNA / Q000235:genetics*; D015894:Genome, Human; D016045:Human Genome Project; D006801:Humans; D014158:Transcription, Genetic
D004247:DNA