The assessment of mucociliary clearance using monodisperse 99mTc-tagged red blood cells.
To assess mucociliary clearance rates of the lungs using a monodisperse particle of constant volume, we investigated the possibility of using a patient's own red blood cells. The cells are tagged with 99mTechnetium. The procedure was performed on two groups of volunteers. The test was found to be very reliable (98%). A second group was studied with the administration of a placebo or 400 mg Aminophylline during the acquisition of the data. The expected response could be seen in 81% of the cases studied.
Botha
U M
UM
Department of Medical Physics, Medical University of South Africa.
Strydom
W J
WJ
Brandt
H D
HD
D000328:Adult; D000336:Aerosols; D000628:Aminophylline; D004912:Erythrocytes; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D009079:Mucociliary Clearance / Q000502:physiology*; D010316:Particle Size; D011877:Radionuclide Imaging; D015203:Reproducibility of Results; D013667:Technetium
D000336:Aerosols; D000628:Aminophylline; D013667:Technetium