Hypereosinophilic syndrome in childhood appearing as inflammatory bowel disease.
A 7-year-old girl with hypereosinophilic syndrome is described, the first such patient to present with inflammatory bowel disease. Hepatosplenomegaly, anaemia, and hypergammaglobulinaemia were also prominent features. Colonoscopy revealed a frank colitis of nonspecific histologic appearance. An elemental diet was unhelpful, but there was a prompt clinical and partial haematological response to systemic steroids. She has remained well receiving a small maintenance dose of prednisolone for 3 years.
Falade
A G
AG
Institute of Child Health, University of Birmingham, England.
Darbyshire
P J
PJ
Raafat
F
F
Booth
I W
IW
D002648:Child; D003092:Colitis / Q000209:etiology* / Q000473:pathology; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000209:etiology / Q000473:pathology; D004802:Eosinophilia / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D013577:Syndrome