Electron imaging and diffraction study of individual crystals of bone, mineralized tendon and synthetic carbonate apatite.
A transmission electron microscope study of carbonate apatite crystals isolated from bone and mineralizing tendon, as well as those produced synthetically under approximated-physiological conditions, shows that they are thin irregular shaped plates. Electron diffraction patterns of individual crystals confirm that the large developed crystal face is (100), and that the longest dimensions of the biogenic crystals are aligned with the crystallographic c axes. As the latter are also aligned with collagen fibril axes, the observations provide additional information on the tissue organization itself. The marked similarity between the biologic and synthetic crystals suggests that the biological environment in which the crystals form may not be primarily responsible for controlling their shape.
Moradian-Oldak
J
J
Department of Structural Chemistry, Weizmann Institute of Science, Rehovot, Israel.
Weiner
S
S
Addadi
L
L
Landis
W J
WJ
Traub
W
W
D000818:Animals; D001031:Apatites / Q000737:chemistry* / Q000302:isolation & purification; D001842:Bone and Bones / Q000737:chemistry*; D003460:Crystallization; D008854:Microscopy, Electron; D008903:Minerals / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D013710:Tendons / Q000737:chemistry*; D014422:Turkeys; D014961:X-Ray Diffraction
D001031:Apatites; D008903:Minerals; C030782:carboapatite