Preliminary studies on the antiinflammatory and analgesic activities of Calotropis procera root extract.
A chloroform-soluble fraction from Calotropis procera roots showed significant dose-related antiinflammatory activity in rats using the pharmacologic models of carrageenin-induced pedal oedema, cotton pellet granuloma and formaldehyde-induced arthritis. In addition, significant analgesic potential was demonstrated using acetic acid-induced writhing in mice.
Basu
A
A
Department of Pharmaceutical Technology, Jadavpur University, Calcutta, India.
Chaudhuri
A K
AK
D000700:Analgesics; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001169:Arthritis, Experimental / Q000517:prevention & control; D002351:Carrageenan; D004487:Edema / Q000139:chemically induced / Q000517:prevention & control; D005557:Formaldehyde; D006099:Granuloma / Q000517:prevention & control; D007194:India; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000032:analysis*; D051381:Rats
D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D010936:Plant Extracts; D005557:Formaldehyde; D002351:Carrageenan