Isolated thrombocytopenia after bone marrow transplantation in Cooley anemia: report of one case.
A nine-year-old boy, victim of Cooley anemia, received allogeneic bone marrow transplantation with his younger brother serving as the histocompatible donor. The myeloid and erythroid series recovered very quickly, but his platelet count never reached 10(5)/mm3 until the 220th day. Platelet-associated IgG (PAIgG) was checked on the 137th and 305th day with the level of 31.75 fg/pl and 6.84 fg/pl, respectively. Immune mediated process was considered to be the cause of his prolonged thrombocytopenia.
Teng
R J
RJ
Department of Pediatrics, National Taiwan University Hospital, Taipei, R.O.C.
Lin
K H
KH
Shen
M C
MC
D000818:Animals; D001792:Blood Platelets / Q000276:immunology; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D011817:Rabbits; D013789:Thalassemia / Q000628:therapy*; D013921:Thrombocytopenia / Q000209:etiology*
D007074:Immunoglobulin G