Immunocytochemical evidence for the site of O-methylation in rat dental pulp.
Immunocytochemical observations by light and electron microscopy of catechol-O-methyltransferase (COMT) were conducted in dental pulp by use of a specific antibody to soluble rat-liver COMT and the peroxidase-antiperoxidase technique. Immunoreactive deposits were found in macrophages. The pattern of localization suggests that COMT may function in extraneuronal inactivation of catecholamines in dental pulp.
Inoue
K
K
Department of Oral Anatomy, Okayama University, Dental School, Japan.
Nishino
T
T
Creveling
C R
CR
D000818:Animals; D002394:Catechol O-Methyltransferase / Q000378:metabolism*; D002462:Cell Membrane / Q000648:ultrastructure; D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D003782:Dental Pulp / Q000166:cytology / Q000201:enzymology*; D007124:Immunoenzyme Techniques; D008264:Macrophages / Q000166:cytology / Q000201:enzymology; D008297:Male; D008745:Methylation; D051381:Rats; D011919:Rats, Inbred Strains
D002394:Catechol O-Methyltransferase