title: Enamel pitting. A common sign of tuberous sclerosis.
abstract: Dental enamel pitting as a diagnostic sign of tuberous sclerosis (TSC) is explored and a protocol for the oral examination of patients and individuals at risk is described. In the study, 50 patients with TSC and 250 control patients were examined for dental enamel pitting. A simple clinical protocol was established for examination using a dental disclosing solution swabbed on dry teeth. The incidence of enamel pitting in the adult dentition of patients with TSC was 100%, whereas that in the adult dentition of the control group was 7%. The simplicity of the test and the high probability of occurrence in TSC make it an important tool in the diagnosis of this serious genetic disease.
authors.forename: G
authors.initials: G
authors.lastname: Mlynarczyk
mesh_terms: D003744:Dental Enamel Hypoplasia / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D014402:Tuberous Sclerosis / Q000150:complications / Q000473:pathology*