[Efficacy of intra-arterial fibrinolysis in subacute atheromatous ischemia of the lower limbs].
The study of 44 patients treated with intra-arterial fibrinolysis is reported. All these patients had an impending subacute ischemia of the lower limbs, a major complication of atheromatous disease. The criteria for patient selection were clinical, hemodynamic and radiological. The procedure of the treatment associating Urokinase, Heparin and Naphthidrofluril are defined, as well as its follow-up. The results have been evaluated according to the clinical and radiological improvement. 2 patients died when the treatment ceased and 10 were amputated, ie 27% of failures. The fibrinolytic treatment allowed identifying the patients who might quickly receive an additional treatment. In our experience, this treatment seems to improve the prognosis of impending subacute ischemia.
Enon
B
B
Service de Chirurgie Vasculaire et Thoracique, Centre hospitalier Régional et Universitaire d'Angers.
Chevalier
J M
JM
Talha
H
H
Lescalie
F
F
L'Hoste
P
P
Pillet
J
J
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001161:Arteriosclerosis / Q000188:drug therapy*; D005069:Evaluation Studies as Topic; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007261:Infusions, Intra-Arterial; D007269:Injections, Intra-Arterial; D007511:Ischemia / Q000188:drug therapy*; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D015912:Thrombolytic Therapy
D005343:Fibrinolytic Agents
Efficacité de la fibrinolyse intra-artérielle dans l'ischémie subaiguë d'origine athéromateuse des membres inférieurs.