title: Jugular venous 'a' wave in dilated cardiomyopathy: sign of abbreviated right ventricular filling time.
abstract: OBJECTIVE
  To study the mechanisms underlying the high venous pressure often seen in patients with dilated cardiomyopathy.
  
  
  METHODS
  Retrospective and prospective examination of the pattern of flow in the superior vena cava, cardiac echo-Doppler studies, and recordings of the jugular venous pulse.
  
  
  METHODS
  A tertiary referral cardiac centre. PATIENTS PARTICIPANTS: 23 patients with dilated cardiomyopathy, all with functional mitral and tricuspid regurgitation.
  
  
  RESULTS
  Two patterns of venous pulse were seen: a dominant 'a' wave and 'x' descent, with systolic flow in the superior vena cava (group 1, n = 11), and a dominant 'v' wave with 'y' descent and diastolic flow in the superior vena cava (group 2, n = 12). A comparison of group 1 and group 2 showed: age (mean (SD] 58 (12) v 61 (6) years, left ventricular end diastolic dimension 7.0 (0.7) cm in both groups, right ventricular short axis 3.3 (0.6) v 3.6 (0.5) cm and long axis 7.3 (0.5) v 7.1 (0.7) cm, and duration of tricuspid regurgitation 350 (65) v 370 (50) ms. The RR interval (550 (100) v 680 (80) ms) and right ventricular filling time (150 (30) v 290 (50) ms) were significantly shorter in group 1. In all patients in group 2 right ventricular filling time was more than 200 ms with separate E and A waves on the tricuspid Doppler echocardiogram, while in all group 1 patients it was less than 200 ms with a single summation peak. In nine patients in group 1, the right ventricular filling time was limited by prolonged tricuspid regurgitation and in the remaining two by prolonged isovolumic relaxation time (215 (80) ms), so that it was consistently significantly less than that of the left ventricle.
  
  
  CONCLUSIONS
  In patients with dilated cardiomyopathy, right ventricular filling time may be so short that it limits stroke volume. Such patients can be recognised by a dominant 'a' wave on the jugular venous pulse. Patients in whom the right ventricular filling time was longer showed a dominant 'v' wave. Both groups can present as "congestive heart failure".
authors.affiliation: Royal Brompton National Heart and Lung Hospital, London.
authors.forename: C H
authors.initials: CH
authors.lastname: Lee
authors.forename: H B
authors.initials: HB
authors.lastname: Xiao
authors.forename: D G
authors.initials: DG
authors.lastname: Gibson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure / Q000502:physiology; D002311:Cardiomyopathy, Dilated / Q000503:physiopathology*; D004452:Echocardiography; D005260:Female; D006801:Humans; D007601:Jugular Veins / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011674:Pulse / Q000502:physiology; D012039:Regional Blood Flow / Q000502:physiology; D012189:Retrospective Studies; D014683:Vena Cava, Superior / Q000502:physiology; D016278:Ventricular Function, Right / Q000502:physiology*