Structure of the capsular polysaccharide from Actinobacillus pleuropneumoniae serotype 7.
The structure of the capsular polysaccharide antigen of A. pleuropneumoniae serotype 7 was determined using 1D- and 2D-n.m.r. methods. Dephosphorylation, methylation, and g.l.c.-mass spectrometry methods were used to confirm the analysis. The type-7 specific polysaccharide was a high-molecular-weight teichoic acid-type polymer of D-galactose, glycerol, and phosphate (2:1:1), composed of glycosylglycerol repeating units joined through monophosphate diester linkages and with the structure: [formula: see text]
Beynon
L M
LM
Division of Biological Sciences, National Research Council of Canada, Ottawa, Ontario.
Perry
M B
MB
Richards
J C
JC
D000188:Actinobacillus / Q000032:analysis* / Q000145:classification / Q000276:immunology; D000942:Antigens, Bacterial / Q000737:chemistry; D016667:Bacterial Capsules; D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D015394:Molecular Structure; D011135:Polysaccharides, Bacterial / Q000737:chemistry* / Q000276:immunology; D012703:Serotyping
D000942:Antigens, Bacterial; D011135:Polysaccharides, Bacterial; C068916:capsular polysaccharide type 7, Actinobacillus pleuropneumoniae