[Changes in neuronal structure and activity of various oxidation- reduction enzymes in the cerebellum after continuous long-term general low-frequency vibration].
In 84 white non-inbred rats, subjected to the effect of total continuous low-frequency vibration (8 Hz, 95 dB) for 1, 3, 7, 14, 20, 30 days, morphological and histoenzymatic changes have been studied in the nuclear neurons and in the cerebellar cortex. The former are presented as axonal reactions, as chromatolysis of various degree of manifestation, as changes in amount of hypochromic neurons, as glial reactions of various forms. They are interpreted as reactive and are of stage character. The histoenzymatic changes of the oxidation-reduction enzymes come to alterations in the activity of NAD and NADPH-dependent enzymes ratio and possible transformation of the cycle of tricarboxylic acids into the "incomplete" one. The structural and histoenzymatic changes correlate with each other.
Il'in
I I
II
Nasibullin
B A
BA
Zherebitskiĭ
V A
VA
D000818:Animals; D002531:Cerebellum / Q000201:enzymology / Q000473:pathology*; D002952:Citric Acid Cycle / Q000502:physiology; D008959:Models, Neurological; D009474:Neurons / Q000201:enzymology / Q000473:pathology*; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013312:Stress, Physiological / Q000201:enzymology / Q000473:pathology*; D013997:Time Factors; D014732:Vibration / Q000009:adverse effects*
D010088:Oxidoreductases
Izmeneniia struktury neĭronov i aktivnosti nekotorykh okislitel'no- vosstanovitrel'nykh fermentov v mozzhechke pri nepreryvnom dlitel'nom deĭstvii obshcheĭ nizkochastotnoĭ vibratsii.