title: Translocation t(8;16)(p11;p13) in neonatal acute monocytic leukaemia.
abstract: A recent report demonstrated that t(8;16) (p11;p13) may be linked to acute monocytic leukaemia (AMoL) of differentiated subtype (M5b) with active haemophagocytosis by leukaemic cells. Only two cases of neonatal AMoL with t(8;16) (p11;p13) have been reported; M5b with haemophogocytosis and M5a. We report a case of neonatal AMoL (M5b) with t(8;16)(p11;p13), but haemophagocytosis by the leukaemic cells was not detected.
authors.affiliation: Department of Paediatrics, University of Tsukuba, Ibaraki-ken, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Hanada
authors.forename: I
authors.initials: I
authors.lastname: Ono
authors.forename: Y
authors.initials: Y
authors.lastname: Minosaki
authors.forename: N
authors.initials: N
authors.lastname: Moriyama
authors.forename: S
authors.initials: S
authors.lastname: Nakahara
authors.forename: A
authors.initials: A
authors.lastname: Ohtsu
mesh_terms: D002885:Chromosomes, Human, Pair 16; D002898:Chromosomes, Human, Pair 8; D006801:Humans; D007231:Infant, Newborn; D007948:Leukemia, Monocytic, Acute / Q000235:genetics* / Q000503:physiopathology; D010587:Phagocytosis / Q000502:physiology; D014178:Translocation, Genetic / Q000235:genetics*