Stimulation by adjuvants of cell-mediated immune response in Plasmodium berghei infected mice.
Immunological adjuvants (alum, liposomes and saponin) were utilized to stimulate cell-mediated immune response in Plasmodium berghei infected Balb/c mice. It was shown that malaria antigen mixed with adjuvant induced appreciably delayed type hypersensitivity and production of migration inhibition factor compared to antigen alone.
Beuria
M K
MK
Department of Immunology, Regional Medical Research Centre (ICMR), Bhubaneswar, India.
Ravindran
B
B
Das
M K
MK
D000276:Adjuvants, Immunologic; D000818:Animals; D000953:Antigens, Protozoan / Q000276:immunology*; D002464:Cell Migration Inhibition; D005260:Female; D006968:Hypersensitivity, Delayed; D008263:Macrophage Migration-Inhibitory Factors / Q000032:analysis; D008288:Malaria / Q000276:immunology*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D010962:Plasmodium berghei / Q000276:immunology*
D000276:Adjuvants, Immunologic; D000953:Antigens, Protozoan; D008263:Macrophage Migration-Inhibitory Factors