title: Direct monitoring by carbon-13 nuclear magnetic resonance spectroscopy of the metabolism and metabolic rate of 13C-labeled compounds in vivo.
abstract: Carbon-13 nuclear magnetic resonance spectroscopy has been used to observe the transformations of [1-13C]-D-glucose to [1,1'-13C2]-D-trehalose, and [3-13C]-L-alanine to [2-13C]-L-glutamic acid in the living body of Gryllodes sigillatus. [3-13C]-D-Alanine was not metabolized. The metabolic rate of [1-13C]-D-glucose was found to be altered by prior injection of boric acid.
authors.affiliation: Department of Medicinal Chemistry, Meiji College of Pharmacy, Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Iida
authors.forename: O
authors.initials: O
authors.lastname: Hidoh
authors.forename: J
authors.initials: J
authors.lastname: Fukami
authors.forename: M
authors.initials: M
authors.lastname: Kajiwara
mesh_terms: D000409:Alanine / Q000378:metabolism*; D000818:Animals; D002247:Carbon Isotopes; D005947:Glucose / Q000378:metabolism*; D006135:Gryllidae / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*
chemical_list: D002247:Carbon Isotopes; D005947:Glucose; D000409:Alanine