title: Autism associated with marker chromosome.
abstract: Six boys who all showed the combination of moderate-severe mental retardation, autistic behavior, and mild-moderate physical stigmatization are described. Muscular hypotonia, epilepsy, and kyphoscoliosis were associated features in several cases, as were extremes of short stature and low weight. A supernumerary chromosome was found in all six cases, and it appears that there may be a separate syndrome associated with partial trisomy of chromosome 15.
authors.affiliation: Department of Pediatrics, University of Göteborg, Sweden.
authors.forename: C
authors.initials: C
authors.lastname: Gillberg
authors.forename: S
authors.initials: S
authors.lastname: Steffenburg
authors.forename: J
authors.initials: J
authors.lastname: Wahlström
authors.forename: I C
authors.initials: IC
authors.lastname: Gillberg
authors.forename: A
authors.initials: A
authors.lastname: Sjöstedt
authors.forename: T
authors.initials: T
authors.lastname: Martinsson
authors.forename: S
authors.initials: S
authors.lastname: Liedgren
authors.forename: O
authors.initials: O
authors.lastname: Eeg-Olofsson
mesh_terms: D000293:Adolescent; D000328:Adult; D001321:Autistic Disorder / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D002884:Chromosomes, Human, Pair 15; D004200:Diseases in Twins; D005819:Genetic Markers; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics; D008297:Male; D014314:Trisomy
chemical_list: D005819:Genetic Markers