[The effect of low-frequency vibration on GABA metabolism in brain structures].
Low-frequency vibration, irrespective of its duration (20 Hz, A = 0.4 mm), is shown to increase GABA level, glutamatedecarboxylase enzyme activity (EC 4.1.1.15) in the large hemispheres, cerebellum, brain stem of adult male rats (12 months). Meanwhile GABA aminotransferase activity (EC 2.6.1.19) remains, mainly, unchanged. The observed shifts are more clear under 30 min vibration than under 7h and 30 day effects. Glutaminic and aspartic acids content increases under 30 min and decreases under 7h and 30 day vibration in the given brain structures.
Safarov
M I
MI
Kerimov
S A
SA
D000612:4-Aminobutyrate Transaminase / Q000378:metabolism; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001921:Brain / Q000378:metabolism*; D001923:Brain Chemistry; D004590:Electrophoresis, Paper; D005968:Glutamate Decarboxylase / Q000378:metabolism; D008297:Male; D051381:Rats; D013997:Time Factors; D014732:Vibration; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D000596:Amino Acids; D005680:gamma-Aminobutyric Acid; D000612:4-Aminobutyrate Transaminase; D005968:Glutamate Decarboxylase
Vliianie nizkochastotnoĭ vibratsii na obmen GAMK v nekotorykh strukturakh golovnogo mozga.