Aureobasidium infection of the jaw.
A 32-yr-old white North American male resident of Norway presented with an asymptomatic radiolucency first identified 3 yr after the removal of an impacted mandibular right third molar in Southern California 16 yr previously. Surgical exploration revealed an intraosseous cavity filled with a black, homogeneous, gelatinous substance thought to be foreign material, but which was diagnosed histologically as containing black yeasts. Cultivation of a microbiologic sample for 6 wk grew black yeast-like colonies. The yeast isolate was identified as an Aureobasidium species different from the typical A. pullulans. A blood sample was negative with regard to antibodies both with double diffusion technique and ELISA. Also, examination with respect to dermatologic manifestations gave negative results. Flucytocin 10 g/d was administered systemically for 30 d. Six months postoperatively bone regeneration was satisfactory radiologically.
Koppang
H S
HS
Department of Oral Pathology, University of Oslo, Norway.
Olsen
I
I
Stuge
U
U
Sandven
P
P
D000328:Adult; D005437:Flucytosine / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D003904:Mitosporic Fungi / Q000302:isolation & purification*; D008964:Molar, Third; D009181:Mycoses / Q000188:drug therapy; D010019:Osteomyelitis / Q000188:drug therapy / Q000382:microbiology; D011859:Radiography; D014081:Tooth Extraction; D015003:Yeasts / Q000302:isolation & purification*
D005437:Flucytosine