title: Effect of Artocarpus heterophyllus and Asteracanthus longifolia on glucose tolerance in normal human subjects and in maturity-onset diabetic patients.
abstract: Investigations were carried out to evaluate the effects of hot-water extracts of Artocarpus heterophyllus leaves and Asteracanthus longifolia whole plant material on the glucose tolerance of normal human subjects and maturity-onset diabetic patients. The extracts of both Artocarpus heterophyllus and Asteracanthus longifolia significantly improved glucose tolerance in the normal subjects and the diabetic patients when investigated at oral doses equivalent to 20 g/kg of starting material.
authors.affiliation: Department of Biochemistry, Faculty of Medicine, University of Ruhuna, Galle, Sri Lanka.
authors.forename: M R
authors.initials: MR
authors.lastname: Fernando
authors.forename: N
authors.initials: N
authors.lastname: Wickramasinghe
authors.forename: M I
authors.initials: MI
authors.lastname: Thabrew
authors.forename: P L
authors.initials: PL
authors.lastname: Ariyananda
authors.forename: E H
authors.initials: EH
authors.lastname: Karunanayake
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000378:metabolism*; D005951:Glucose Tolerance Test; D006801:Humans; D007004:Hypoglycemic Agents; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000032:analysis*; D013188:Sri Lanka
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D010936:Plant Extracts