title: Amputation for gangrene of the limbs following severe meningococcal infection.
abstract: Five cases of severe meningococcal infection in children and young adults with gangrene leading to major amputation are described. They are associated with necrosis of the skin and soft tissue, intravascular coagulation and shock. The surgical options, prosthetic implications and the consequent rehabilitation outcome are discussed.
authors.affiliation: Disablement Services Centre, Birmingham, UK.
authors.forename: T L
authors.initials: TL
authors.lastname: Landham
authors.forename: D
authors.initials: D
authors.lastname: Datta
authors.forename: H C
authors.initials: HC
authors.lastname: Nirula
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000671:Amputation, Surgical; D002648:Child; D002675:Child, Preschool; D005121:Extremities / Q000601:surgery*; D005260:Female; D005734:Gangrene / Q000209:etiology / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007223:Infant; D008297:Male; D008589:Meningococcal Infections / Q000150:complications*; D009336:Necrosis