title: Use of botulinum toxin in strabismus after retinal detachment surgery.
abstract: Botulinum toxin was used to treat 20 patients with strabismus after retinal detachment surgery. Preinjection motility deviations ranged from 10 to 60 prism diopters (D). Postinjection deviations ranged from 0 to 20 prism D, with 75% being 10 D or less. Eighty-five percent achieved fusion that persisted, with 73% requiring only one or two injections. Only muscles in the eye that had undergone retinal reattachment surgery were injected. The average period of follow-up was 12 months. Complications were rare and all resolved spontaneously. Botulinum toxin appears to be useful as a primary treatment modality for persistent strabismus following retinal detachment surgery, possibly obviating the need for complicated strabismus surgery.
authors.affiliation: Duke University Eye Center, Duke University Medical Center, Durham, NC 27710.
authors.forename: V B
authors.initials: VB
authors.lastname: Petitto
authors.forename: E G
authors.initials: EG
authors.lastname: Buckley
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001905:Botulinum Toxins / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009801:Oculomotor Muscles / Q000187:drug effects; D011183:Postoperative Complications / Q000188:drug therapy*; D012163:Retinal Detachment / Q000601:surgery*; D012591:Scleral Buckling; D013285:Strabismus / Q000188:drug therapy*; D014792:Visual Acuity
chemical_list: D001905:Botulinum Toxins