[Ectasing cholangitis and secondary biliary cirrhosis following intra-arterial hepatic chemotherapy. Treatment by liver transplantation].
A case of ectasing cholangitis, following intra-arterial chemotherapy with discontinuous infusion of fluorouracile, is described. The severe destruction of the intra-hepatic biliary ducts led to the constitution of large cavities in continuity with the biliary tree. These cavities were responsible for images which were mistakenly thought to be metastases. Consequently, secondary biliary cirrhosis developed, requiring orthotopic liver transplantation.
Pitre
J
J
Clinique Chirurgical, Hôpital Cochin, Paris.
Houssin
D
D
Louvel
A
A
Vigouroux
C
C
Gaudric
M
M
Chapuis
Y
Y
D000230:Adenocarcinoma / Q000188:drug therapy; D000328:Adult; D015209:Cholangitis, Sclerosing / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000601:surgery; D005260:Female; D005472:Fluorouracil / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007261:Infusions, Intra-Arterial; D008105:Liver Cirrhosis, Biliary / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000601:surgery; D016031:Liver Transplantation / Q000379:methods*; D012811:Sigmoid Neoplasms / Q000188:drug therapy; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
D005472:Fluorouracil
Cholangite ectasiante et cirrhose biliaire secondaire après chimiothérapie intra-artérielle hépatique. Traitement par transplantation hépatique.