[Study of cardio- and hemodynamic reactions to administration of GABA into the neuronal structures of the ventrolateral area of the medulla oblongata of cats].
The data obtained in acute experiments on cats have indicated that the most GABA-sensitive injected neuronal structures in the ventrolateral medulla appear to be located in the vicinity to the roots of the XII cranial nerves. GABA injected into these structures just rostrally to the roots induced hypotensive reactions due to heart rate and myocardial contractile activity decrease, besides inhibition of sympathetic vasoconstrictor influences. GABA injected into the neuronal structures in the caudal ventrolateral medulla induced hypertensive reactions, to a large extent due to increase in heart rate and contractile activity of myocardium.
Shapoval
L N
LN
Pobegaĭlo
L S
LS
Sagach
V F
VF
D000818:Animals; D002415:Cats; D003864:Depression, Chemical; D006321:Heart / Q000294:innervation* / Q000502:physiology; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D008526:Medulla Oblongata / Q000166:cytology / Q000187:drug effects* / Q000502:physiology; D009200:Myocardial Contraction / Q000187:drug effects* / Q000502:physiology; D009474:Neurons / Q000187:drug effects / Q000502:physiology; D013268:Stimulation, Chemical; D013564:Sympathetic Nervous System / Q000187:drug effects* / Q000502:physiology; D013997:Time Factors; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology*
D005680:gamma-Aminobutyric Acid
Issledovanie kardio- i gemodinamicheskikh reaktsiĭ na vvedenie GAMK v neĭronnye struktury ventrolateral'noĭ oblasti prodolgovatogo mozga koshki.