Cell-mediated cytotoxicity: ATP as an effector and the role of target cells.
Cell-mediated cytotoxicity involves a number of distinct mechanisms as well as the active participation of the target cell. Recently, several investigators have demonstrated that extracellular ATP can act as a cytotoxic effector.
Steinberg
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Washington University School of Medicine, Division of Infectious Diseases, St Louis 63110.
Di Virgilio
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D000255:Adenosine Triphosphate / Q000494:pharmacology / Q000502:physiology*; D000818:Animals; D003602:Cytotoxicity, Immunologic / Q000502:physiology*; D004247:DNA / Q000187:drug effects; D007111:Immunity, Cellular / Q000502:physiology*; D051379:Mice; D018160:Receptors, Cytoplasmic and Nuclear; D011983:Receptors, Purinergic / Q000502:physiology
C037688:ADP-ATP carrier receptor; D018160:Receptors, Cytoplasmic and Nuclear; D011983:Receptors, Purinergic; D000255:Adenosine Triphosphate; D004247:DNA