title: Humanized antibodies for therapy.
abstract: Protein engineering has made it possible to combine the binding sites of murine antibodies with human antibody regions. Antibodies constructed in this way have important advantages for therapy.
authors.affiliation: Protein Design Labs, Inc., Mountain View, California 94043.
authors.forename: M S
authors.initials: MS
authors.lastname: Co
authors.forename: C
authors.initials: C
authors.lastname: Queen
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000235:genetics / Q000276:immunology / Q000627:therapeutic use*; D000941:Antigens / Q000276:immunology; D001666:Binding Sites, Antibody / Q000235:genetics; D006801:Humans; D008214:Lymphocytes / Q000276:immunology; D051379:Mice; D015202:Protein Engineering; D011994:Recombinant Proteins / Q000627:therapeutic use
chemical_list: D000911:Antibodies, Monoclonal; D000941:Antigens; D011994:Recombinant Proteins