Resistance of rat embryonic heart cells to the cytotoxic effects of cyclophosphamide does not involve aldehyde dehydrogenase-mediated metabolism.
Mirkes
P E
PE
Department of Pediatrics, University of Washington, Seattle 98195.
Ellison
A
A
Little
S A
SA
D000444:Aldehyde Dehydrogenase / Q000378:metabolism; D000818:Animals; D002470:Cell Survival / Q000187:drug effects; D003520:Cyclophosphamide / Q000031:analogs & derivatives / Q000633:toxicity*; D004351:Drug Resistance; D004622:Embryo, Mammalian / Q000187:drug effects*; D006321:Heart / Q000187:drug effects* / Q000196:embryology; D066298:In Vitro Techniques; D009206:Myocardium / Q000166:cytology / Q000201:enzymology; D051381:Rats; D013723:Teratogens / Q000633:toxicity
D013723:Teratogens; C014668:4-methylcyclophosphamide; D003520:Cyclophosphamide; D000444:Aldehyde Dehydrogenase