title: Methods to diminish intraoperative blood loss.
abstract: With the subcutaneous injection of a saline-vasopressor solution under donor sites and debrided areas, a significant reduction in intraoperative blood transfusions was accomplished. No problems in healing of donor sites or skin grafts were encountered. Vasodilating anesthetics and ketamine can overcome the local vasopressor action. Discontinuing or reducing the concentration of these agents results in less bleeding from the wound.
authors.affiliation: Burn Center, University of Alabama Hospital, Birmingham 35294.
authors.forename: L
authors.initials: L
authors.lastname: Kahalley
authors.forename: A R
authors.initials: AR
authors.lastname: Dimick
authors.forename: R W
authors.initials: RW
authors.lastname: Gillespie
mesh_terms: D016063:Blood Loss, Surgical / Q000517:prevention & control*; D002056:Burns / Q000601:surgery*; D003646:Debridement; D004837:Epinephrine / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007267:Injections; D007431:Intraoperative Complications / Q000517:prevention & control*; D012462:Saline Solution, Hypertonic / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D012462:Saline Solution, Hypertonic; D004837:Epinephrine