title: [Immunological and biochemical factors associated with spontaneous bacterial peritonitis].
abstract: A prospective study (June 1988-December 1989) of all patients admitted with ascites due to cirrhosis was undertaken: Biochemical and immunological factors which may have significance in the development of spontaneous bacterial peritonitis were determined. Among 56 patients (44 males and 12 females) SBP developed in 16% of the group. No age differences were found and the etiology of the cirrhosis was mainly alcoholic. Patients with SBP had lower alpha-2 globulin concentrations: 0.43 +/- 0.12 vs. 0.60 +/- 0.18 g/dl (p less than 0.05) and a lower prothrombin time: 41 +/- 13% vs. 69.5 +/- 13 vs. 69.5 +/- 21% (p less than 0.001). Patients with SBP had also lower ascitic fluid total protein 0.99 +/- 0.4 vs. 1.64 +/- 1.1 g/dl (p less than 0.01) as well as lower alfa-2 globulin: 0.065 +/- 0.012 vs. 0.096 +/- 0.067 g/dl (p less than 0.05); beta globulin, 0.11 +/- 0.047 vs. 0.2 +/- 0.17 g/dl (p less than 0.05); gamma globulin, 0.32 +/- 0.1 vs. 0.52 +/- 0.4 g/dl (p less than 0.05); IgG, 275 +/- 157 vs. 477 +/- 335 g/dl (p less than 0.05); C3, 9.2 +/- 3.2 vs. 17 +/- 13 mg/dl (p less than 0.01) and C4, 2.83 +/- 1.5 vs. 4.66 +/- 3.9 mg/dl (p less than 0.05) than patients without this complication.
authors.affiliation: Clinica de la Concepción, Fundación Jiménez Díaz, Universidad Autónoma, Madrid.
authors.forename: C
authors.initials: C
authors.lastname: García Reinoso
authors.forename: J
authors.initials: J
authors.lastname: Sanz del Forcallo
authors.forename: F
authors.initials: F
authors.lastname: Sáez-Royuela
authors.forename: M
authors.initials: M
authors.lastname: Gómez Rubio
authors.forename: E
authors.initials: E
authors.lastname: Marriott Díaz
authors.forename: A
authors.initials: A
authors.lastname: Brossa Franco
authors.forename: F
authors.initials: F
authors.lastname: Ortiz Maslloréns
authors.forename: C
authors.initials: C
authors.lastname: Hernández Guío
mesh_terms: D000368:Aged; D001202:Ascitic Fluid / Q000737:chemistry; D001424:Bacterial Infections / Q000453:epidemiology / Q000276:immunology* / Q000378:metabolism; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications; D008107:Liver Diseases / Q000150:complications; D008297:Male; D008875:Middle Aged; D010538:Peritonitis / Q000453:epidemiology / Q000276:immunology* / Q000378:metabolism; D011446:Prospective Studies; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology
vernacular_title: Factores inmunológicos y bioquímicos relacionados con la peritonitis bacteriana espontánea.