title: [Drug interactions of cyclosporine. Literature review].
abstract: The cyclosporine is widely used as an immuno-suppressive agent in association with others drugs. Its narrow therapeutic range requires frequent monitoring. We suggest a literature review of suspected or confirmed drug interactions. The classification is presented as: absorption interactions; pharmacokinetic interactions in antiinfectious, anticonvulsants, cardiovascular drugs, H2 antagonists agents, hormonotherapy; pharmacodynamic interactions associated to increased cyclosporine nephrotoxicity.
authors.affiliation: Laboratoire de Pharmacocinétique, CHRU la Milétrie, Poitiers.
authors.forename: S
authors.initials: S
authors.lastname: Bouquet
authors.forename: G
authors.initials: G
authors.lastname: Chapelle
authors.forename: M C
authors.initials: MC
authors.lastname: Perault
authors.forename: E
authors.initials: E
authors.lastname: Rochard
authors.forename: B
authors.initials: B
authors.lastname: Vandel
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000378:metabolism; D002317:Cardiovascular Agents / Q000378:metabolism; D003524:Cyclosporins / Q000378:metabolism* / Q000494:pharmacology; D004347:Drug Interactions; D004357:Drug Synergism; D006801:Humans
chemical_list: D000890:Anti-Infective Agents; D002317:Cardiovascular Agents; D003524:Cyclosporins
vernacular_title: Interactions médicamenteuses de la ciclosporine. Revue de littérature.