[Cerebral hemorrhage associated with phenylpropanolamine].
In recent years, sympathomimetic drugs, including ephedrine, amphetamine and phenylpropanolamine, have been increasingly associated with cerebral haemorrhage and infarction. We report a case of intracranial bleeding in a 37 year-old woman with mononucleosis who took therapeutic doses of phenylpropanolamine. Cerebral CT on admission showed a left-sided intracerebral hematoma. Angiography was normal. Late bleeding occurred on the fourth day. She survived but developed a right-sided cerebral infarction with persistent epilepsy. Her mononucleosis was of moderate severity without bleeding diastesis. We conclude that the intracranial bleedings were secondary to taking phenylpropanolamine.
Strand
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Medisinsk avdeling, Sentralsykehuset i Akershus, Nordbyhagen.
Lund-Tønnesen
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D000328:Adult; D002543:Cerebral Hemorrhage / Q000139:chemically induced* / Q000000981:diagnostic imaging; D005260:Female; D006406:Hematoma / Q000139:chemically induced* / Q000000981:diagnostic imaging; D006801:Humans; D010665:Phenylpropanolamine / Q000009:adverse effects* / Q000737:chemistry; D014057:Tomography, X-Ray Computed
D010665:Phenylpropanolamine
Cerebral blødning assosiert med fenylpropanolamin.