title: Intestinal malrotation: the role of small intestinal dysmotility in the cause of persistent symptoms.
abstract: To investigate the possibility that small intestinal dysmotility is a cause of long-standing and persistent symptoms in patients with malrotation, we retrospectively reviewed 94 patients operated on for intestinal malrotation. In 50 patients operated on during the neonatal period, associated abnormalities were common (24%) and all presented with obstructive symptoms; only three (6%) had continuing mild symptoms the postneonatal period (aged 1 month to 1 year), five of whom (22%) had other abnormalities. Recurrent vomiting was the most common presentation (11/23); only 5 patients (21%) had acute obstruction. Response to operation was good in 18 (78%) and two had persistant symptoms; both died. Twenty-one patients presented beyond infancy (aged greater than 1 year), only 19 of whom had symptoms of less than 2 months' duration. Eight (47%) of those with long-standing symptoms had no relief from operation. Small bowel motility was recorded manometrically in 4 patients with long-standing symptoms. The findings suggest that small intestinal dysmotility may be common in patients with malrotation and persistant symptoms.
authors.affiliation: Institute of Child Health, University of Birmingham, England.
authors.forename: R C
authors.initials: RC
authors.lastname: Coombs
authors.forename: R G
authors.initials: RG
authors.lastname: Buick
authors.forename: P G
authors.initials: PG
authors.lastname: Gornall
authors.forename: J J
authors.initials: JJ
authors.lastname: Corkery
authors.forename: I W
authors.initials: IW
authors.lastname: Booth
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005769:Gastrointestinal Motility; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007415:Intestinal Obstruction / Q000209:etiology; D007422:Intestines / Q000002:abnormalities* / Q000601:surgery; D012008:Recurrence; D012189:Retrospective Studies