title: Tpi-1 and Gapd are linked very closely on mouse chromosome 6.
abstract: Mutations in the structural genes for triosephosphate isomerase and glyceraldehyde-3-phosphate dehydrogenase activity in the mouse, selected after mutagen treatment, were used to estimate the map distance between the two loci. It is shown that Tpi-1 and Gapd are closely linked on chromosome 6, with a recombination frequency of 0.1 +/- 0.1%.
authors.affiliation: GSF-Institut für Säugetiergenetik, Neuherberg, Federal Republic of Germany.
authors.forename: W
authors.initials: W
authors.lastname: Pretsch
authors.forename: A
authors.initials: A
authors.lastname: Neuhäuser-Klaus
authors.forename: S
authors.initials: S
authors.lastname: Merkle
mesh_terms: D000818:Animals; D003433:Crosses, Genetic; D005260:Female; D005796:Genes; D008040:Genetic Linkage; D005987:Glyceraldehyde-3-Phosphate Dehydrogenases / Q000235:genetics* / Q000378:metabolism; D006579:Heterozygote; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D009154:Mutation; D014305:Triose-Phosphate Isomerase / Q000235:genetics* / Q000378:metabolism
chemical_list: D005987:Glyceraldehyde-3-Phosphate Dehydrogenases; D014305:Triose-Phosphate Isomerase