Protein redistribution diet and antiparkinsonian response to levodopa.
Sixteen parkinsonian patients with daily fluctuations in the clinical response to levodopa have been placed on a redistribution protein diet. The diet was virtually protein-free until the evening meal and then unrestricted until bedtime. While on the redistribution protein diet, a group of patients (5 out of 16) had a clear and significant benefit from dietary therapy showing a definite reduction of diurnal motor performance fluctuations. In addition, all patients tended to show an improvement and a more constant response to levodopa treatment. A trial of redistribution protein diet appears a simple, reasonable, worthwhile approach to PD patients who begin to experience oscillating clinical response to levodopa treatment.
Bracco
F
F
Institute of Neurology, University of Padova Medical School, Italy.
Malesani
R
R
Saladini
M
M
Battistin
L
L
D000368:Aged; D003131:Combined Modality Therapy; D004044:Dietary Proteins / Q000008:administration & dosage*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000178:diet therapy* / Q000188:drug therapy*
D004044:Dietary Proteins; D007980:Levodopa