Resedation after bolus administration of midazolam to an infant and its reversal by flumazenil.
A 4-month-old infant was sedated with bolus doses of midazolam, and after initial apparent complete arousal, became unresponsive and hypotonic. Administration of flumazenil enabled differentiation of a residual drug effect from an intracerebral event.
Collins
S
S
Frenchay Hospital, Bristol.
Carter
J A
JA
D000758:Anesthesia; D005442:Flumazenil / Q000627:therapeutic use*; D006408:Hematoma, Subdural / Q000601:surgery*; D006801:Humans; D007223:Infant; D008297:Male; D008874:Midazolam / Q000009:adverse effects* / Q000037:antagonists & inhibitors / Q000493:pharmacokinetics / Q000494:pharmacology
D005442:Flumazenil; D008874:Midazolam