[Systemic lupus erythematosus. 1. Disease manifestations, infections, thrombotic episodes, causes of death and survival in a case load of 173 patients followed for 13.9 years].
One hundred and seventy-three patients had systemic lupus erythematosus according to the 1982-ARA-criteria. The mean disease duration at the time of the study was 16.4 years, and the patients were followed by three Copenhagen clinics for a mean of 13.9 years until 1987/88 or death. Half of the patients had nephropathy, 61 patients developed severe infections, and 39 patients had thrombotic episodes. Fifty-six patients died during the observation period, 24 due to active lupus (12 of kidney failure), 12 because of infections, and 11 because of atherosclerotic cardio-vascular disease. The patients had 10-, 15- and 20-year survival rates of 80, 65 and 48 per cent. The deaths were evenly distributed throughout the observation period.
Halberg
P
P
Hvidovre Hospital, København, reumatologisk afdeling.
Bendixen
G
G
Kriegbaum
N J
NJ
Lorenzen
I
I
Müller
K
K
Olesen
K M
KM
Ullman
S
S
D000328:Adult; D000368:Aged; D002423:Cause of Death; D003718:Denmark; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis / Q000401:mortality; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies
Systemisk lupus erythematosus. 1. Sygdomsmanifestationer, infektioner, trombotiske episoder, dødsåger og overlevelse i et materiale bestående patienter fulgt i gennemsnitlig 13,9 år.