Sjögren-like pluriglandular exocrine insufficiency after drug-induced toxic epidermal necrolysis.
We present the case of a patient that progressively developed xerophthalmia, xerostomia, cutaneous xerosis and exocrine pancreatic insufficiency 3 months after metamizole-induced toxic epidermal necrolysis. Though the association of Sjögren's syndrome and exocrine pancreatic impairment is well established, the Sjögren-like syndrome after drug-induced toxic epidermal necrolysis in association with such a wide exocrine glandular insufficiency has not been previously described, to our knowledge.
Sabán
J
J
Department of Medicine, Hospital Ramón y Cajal, University of Alcalá de Henares, Madrid, Spain.
Pais
J R
JR
Rodríguez
J L
JL
Boixeda
D
D
D004177:Dipyrone / Q000009:adverse effects; D010188:Exocrine Pancreatic Insufficiency / Q000209:etiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000209:etiology*; D013262:Stevens-Johnson Syndrome / Q000150:complications* / Q000209:etiology; D014985:Xerophthalmia / Q000209:etiology; D014987:Xerostomia / Q000209:etiology
D004177:Dipyrone