title: [Role of the lungs in the regulation of the generation of active oxygen forms by leukocytes under normal and pathological conditions].
abstract: Studies conducted in the clinic (in patients with cardiac diseases) and experiments (performed on intact dogs) by means of the hemiluminescent method and the nitroblue tetrazolium test showed that the lungs, in distinction to other organs (heart and others), have a stimulating effect on the generation of active oxygen forms (AOF) by the leukocytes. In this way the lungs may probably play a double role in the organism: potentiate its defence (by intensifying the microbicidal activity of the phagocytes) and facilitate damage (by secretion of AOF by the phagocytes beyond them--into the tissues); the resultant effect depends on the balance of these two types of action. In carcinoma of the lung the stimulating effect of its involved lobe (part) on the leukocytes diminishes.
authors.forename: A Kh
authors.initials: AKh
authors.lastname: Kogan
authors.forename: N I
authors.initials: NI
authors.lastname: Losev
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Biriukov
authors.forename: V A
authors.initials: VA
authors.lastname: Sandrikov
authors.forename: A B
authors.initials: AB
authors.lastname: Tsypin
authors.forename: M
authors.initials: M
authors.lastname: Al'-Khadidi
authors.forename: B M
authors.initials: BM
authors.lastname: Manuĭlov
authors.forename: A L
authors.initials: AL
authors.lastname: Syrkin
authors.forename: G S
authors.initials: GS
authors.lastname: Krotovskiĭ
authors.forename: A P
authors.initials: AP
authors.lastname: Pogromov
mesh_terms: D000818:Animals; D002417:Cattle; D003327:Coronary Disease / Q000097:blood; D004285:Dogs; D006801:Humans; D007962:Leukocytes / Q000378:metabolism*; D008168:Lung / Q000502:physiology*; D008175:Lung Neoplasms / Q000097:blood; D010100:Oxygen / Q000097:blood*; D012016:Reference Values
chemical_list: D010100:Oxygen
vernacular_title: O roli legkikh v reguliatsii generatsii aktivnykh form kisloroda leĭkotsitoami v norme i patologii.