title: CT-guided percutaneous large-bore biopsies in benign and malignant pediatric lesions.
abstract: Thirty-nine consecutive pediatric patients underwent large-bore biopsies of 41 lesions under computed tomography (CT) guidance; general anesthesia was not required. Adequate material was obtained in all patients. There were no false-negative or false-positive results. Typing accuracy was 100% in malignant disease and 92% in benign lesions. No significant complications occurred. Percutaneous large-bore biopsy is a safe, reliable, and time-saving method that obviates the need for open surgery and general anesthesia in the diagnosis of primarily non-resectable lesions, or lesions that do not require resection. Another major advantage over open surgery in malignant disease is the absence of delay in starting urgently needed chemotherapy.
authors.affiliation: Department of Diagnostic Radiology, RWTH Aachen, Germany.
authors.forename: K C
authors.initials: KC
authors.lastname: Klose
authors.forename: R
authors.initials: R
authors.lastname: Mertens
authors.forename: G
authors.initials: G
authors.lastname: Alzen
authors.forename: F
authors.initials: F
authors.lastname: Löer
authors.forename: A
authors.initials: A
authors.lastname: Böcking
mesh_terms: D000293:Adolescent; D001707:Biopsy, Needle / Q000379:methods*; D001847:Bone Diseases / Q000473:pathology*; D001859:Bone Neoplasms / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008171:Lung Diseases / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology; D008297:Male; D013896:Thoracic Diseases / Q000473:pathology*; D014057:Tomography, X-Ray Computed