[Kinetics of reparation of sublethal radiation damage in early hematopoietic precursors].
The authors studied the ability of the CFU-S, forming colonies on the 8th and 11th days after bone marrow cells transplantation, to repair the sublethal radiation damages (SRD), according to Elkind's model. Special attention was given to the kinetics fo reparation for SRD for two subpopulations of CFU (8th- and 11th-days' CFU-S). the 1-6 hour intervals between two equivalent doses of irradiation were made. The ability to repair the SRD of the 11th-days' CFU-S was lower than that of the 8th-days' CFU-S at all time intervals. The maximum reparation of the 8th-days' CFU-S was observed at 5-hour period; and that was twice as high as the maximum reparation of the 11th-days' CFU-S, which was determined at 3-hour interval between the two irradiation doses.
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D000818:Animals; D001853:Bone Marrow / Q000473:pathology / Q000528:radiation effects*; D002452:Cell Count / Q000528:radiation effects; D002588:Cesium Radioisotopes / Q000008:administration & dosage / Q000009:adverse effects*; D003114:Colony-Forming Units Assay; D006410:Hematopoiesis / Q000502:physiology / Q000528:radiation effects*; D006412:Hematopoietic Stem Cells / Q000473:pathology / Q000502:physiology / Q000528:radiation effects*; D008297:Male; D051379:Mice; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000097:blood / Q000473:pathology*; D013997:Time Factors
D002588:Cesium Radioisotopes
Kinetika reparatsii subletal'nykh radiatsionnykh povrezhdeniĭ v rannikh gemopoéticheskikh predshestvennikakh.