Vernix caseo granulomatous meningitis (vernicomyelia).
An apneic and tetraplegic infant with an open lumbosacral myelomeningocele and an Arnold-Chiari malformation is reviewed. An exuberant chronic aseptic meningitis with foreign body giant cells and immunoreactive keratin was present around the spinal cord and brainstem. This paper discusses the recognition and role of granulomatous meningitis in the clinical course and in the pathogenesis of the unusual cerebellar abnormalities found in this infant.
Midha
R
R
Department of Pathology, University of Toronto, Ontario, Canada.
Becker
L E
LE
D000015:Abnormalities, Multiple / Q000473:pathology; D001139:Arnold-Chiari Malformation / Q000150:complications*; D001933:Brain Stem / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008161:Lumbosacral Region; D008297:Male; D008578:Meninges / Q000473:pathology; D008582:Meningitis, Aseptic / Q000150:complications* / Q000473:pathology; D008591:Meningomyelocele / Q000150:complications*; D013116:Spinal Cord / Q000473:pathology; D014708:Vernix Caseosa