Laser photocoagulation for stage 3+ retinopathy of prematurity.
Twenty-two infants with "threshold" stage 3+ retinopathy of prematurity (ROP) were entered into a prospective, randomized clinical trial to compare the efficacy of transscleral cryotherapy versus laser photocoagulation delivered by the indirect ophthalmoscope. Eighteen infants have been followed for at least 3 months. Fifteen of 16 eyes randomized to laser and 9 of 12 eyes randomized to cryotherapy showed regression. The results suggest that laser therapy is as effective as cryotherapy in the treatment of ROP (P = 0.285).
McNamara
J A
JA
Retina Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA.
Tasman
W
W
Brown
G C
GC
Federman
J L
JL
D003452:Cryosurgery; D005260:Female; D005500:Follow-Up Studies; D005654:Fundus Oculi; D005865:Gestational Age; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D053685:Laser Therapy; D008028:Light Coagulation; D008297:Male; D011379:Prognosis; D011446:Prospective Studies; D012178:Retinopathy of Prematurity / Q000601:surgery*