Regulation of MHC class II gene transcription.
The transcriptional regulation of MHC class II genes involves the interaction of DNA-binding proteins with specific DNA sequences. The cis elements of the promoter region have now been well delineated functionally, while the proteins that interact with these elements are just beginning to be identified and their functional importance assessed.
Kara
C J
CJ
Department of Medicine, Harvard Medical School, Boston, Massachusetts 02115.
Glimcher
L H
LH
D000818:Animals; D001483:Base Sequence; D005786:Gene Expression Regulation / Q000187:drug effects; D000949:Histocompatibility Antigens Class II / Q000235:genetics*; D006801:Humans; D008222:Lymphokines / Q000494:pharmacology; D051379:Mice; D008969:Molecular Sequence Data; D011401:Promoter Regions, Genetic; D014157:Transcription Factors / Q000494:pharmacology; D014158:Transcription, Genetic
D000949:Histocompatibility Antigens Class II; D008222:Lymphokines; D014157:Transcription Factors