title: [Evaluation of the quality of radiopharmaceutics].
abstract: The authors considered the interrelationship of clinical requirements and analytical indicators of quality for a group of pharmaceuticals: radionuclide purity (by the criteria of dose load and the quality of visualization); radiochemical purity (interrelationship with a necessary level of accumulation in investigated organs); chemical admixtures (by the criteria of safety and influence on the diagnostic quality; clinical criteria of quality were under discussion); a coefficient of differential accumulation in the system: organ under study-adjacent tissues; specificity; indices of pharmacokinetics, etc. Correct and all-round evaluation of RP quality on the basis of the above criteria determines, to a great extent, a choice of a labeled compound to be used in a specific radionuclide diagnostic method.
authors.forename: V N
authors.initials: VN
authors.lastname: Korsunskiĭ
authors.forename: N F
authors.initials: NF
authors.lastname: Tarasov
authors.forename: G E
authors.initials: GE
authors.lastname: Kodina
authors.forename: A B
authors.initials: AB
authors.lastname: Malinin
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004586:Electrophoresis; D005069:Evaluation Studies as Topic; D011868:Radioisotopes / Q000032:analysis / Q000493:pharmacokinetics / Q000592:standards*; D012449:Safety; D014018:Tissue Distribution
chemical_list: D011868:Radioisotopes
vernacular_title: Otsenka kachestva radiofarmatsevticheskikh preparatov.