Direct monitoring by carbon-13 nuclear magnetic resonance spectroscopy of the metabolism and metabolic rate of 13C-labeled compounds in vivo.
Carbon-13 nuclear magnetic resonance spectroscopy has been used to observe the transformations of [1-13C]-D-glucose to [1,1'-13C2]-D-trehalose, and [3-13C]-L-alanine to [2-13C]-L-glutamic acid in the living body of Gryllodes sigillatus. [3-13C]-D-Alanine was not metabolized. The metabolic rate of [1-13C]-D-glucose was found to be altered by prior injection of boric acid.
Iida
K
K
Department of Medicinal Chemistry, Meiji College of Pharmacy, Tokyo, Japan.
Hidoh
O
O
Fukami
J
J
Kajiwara
M
M
D000409:Alanine / Q000378:metabolism*; D000818:Animals; D002247:Carbon Isotopes; D005947:Glucose / Q000378:metabolism*; D006135:Gryllidae / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*
D002247:Carbon Isotopes; D005947:Glucose; D000409:Alanine