title: [A case of epidural lipomatosis presenting spinal ataxia].
abstract: A 41-year-old man was doing well until July 1989, when he noted numbness over soles, followed 4 months later by difficulty in walking. These symptoms were progressively getting worse, and he was admitted to our department on June 12, 1990. General physical examination was unremarkable. Neurologically cranial nerves were intact except old right, traumatic strabismus. Muscle tone and deep tendon reflexes were normal throughout, but bilateral Babinski and Chaddock reflexes were present. Mild weakness of lower extremities were found on muscle testing (4/5). In sensory system, superficial sensory disturbance below T10 was seen, and markedly diminished vibration and position senses of lower extremities were noted. Cerebellar test was intact, although unsteadiness was found on heel-shin test. Romberg sign was definitely positive. His gait was wide-based and ataxic. Laboratory data showed no abnormalities in CBC, chemistry, urinalysis, serological tests and endocrinological examinations. Spinal MRI (Siemens 1.5 Tesla) showed abnormal deposition of epidural fatty tissues compressing spinal cord with flattening of cord from T4 to T8. Spinal ataxia as compressive myelopathy due to epidural lipomatosis was considered and he underwent laminectomy from T4 to T8 with improvement in walking. Epidural lipomatosis is an unusual cause of spinal cord compression, presenting compressive myelopathy, radiculopathy, cauda equina syndrome, intermittent claudication, or back pain. Most of cases were associated with long-term administration of adrenocortical steroid hormone, or underlying diseases, except only 3 cases including ours. This is the first case of spinal epidural lipomatosis presenting progressive gait disturbance due to spinal ataxia.
authors.affiliation: Department of Neurology, Hokkaido University School of Medicine.
authors.forename: K
authors.initials: K
authors.lastname: Tsuzaka
authors.forename: T
authors.initials: T
authors.lastname: Takada
authors.forename: F
authors.initials: F
authors.lastname: Moriwaka
authors.forename: K
authors.initials: K
authors.lastname: Tashiro
authors.forename: M
authors.initials: M
authors.lastname: Akino
mesh_terms: D000328:Adult; D001259:Ataxia / Q000175:diagnosis / Q000209:etiology*; D015174:Epidural Neoplasms / Q000150:complications*; D006801:Humans; D008068:Lipomatosis / Q000150:complications*; D008279:Magnetic Resonance Imaging; D008297:Male; D013117:Spinal Cord Compression / Q000175:diagnosis / Q000209:etiology*