title: Effects of intracerebroventricular histamine injection on circadian activity phase entrainment during rapid illumination changes.
abstract: Histamine is reported to have different effects on shifting the circadian activity phase depending on its circadian administration time (CT). The delay-sensitive period is CT 12-15, and the advance-sensitive period is CT 0-3. The activity phase of rats was entrained by a new light-dark cycle within a week in groups treated with either saline or i.c.v. histamine at CT 12-15. However, on treatment at CT 0-3 the activity phase of the group treated with histamine was entrained by the new light-dark cycle in half the period required for entrainment in the control group.
authors.affiliation: Department of Pharmacology II, Faculty of Medicine, Osaka University, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Itowi
authors.forename: A
authors.initials: A
authors.lastname: Yamatodani
authors.forename: T
authors.initials: T
authors.lastname: Mochizuki
authors.forename: H
authors.initials: H
authors.lastname: Wada
mesh_terms: D000204:Activity Cycles; D000818:Animals; D002552:Cerebral Ventricles / Q000187:drug effects / Q000502:physiology*; D002940:Circadian Rhythm / Q000187:drug effects*; D006632:Histamine / Q000008:administration & dosage / Q000494:pharmacology*; D007276:Injections, Intraventricular; D008027:Light; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D006632:Histamine