title: [The special problem of insect venom allergy in childhood].
abstract: Natural history of hymenoptera sting allergy is less life threatening in children than in adults. We evaluated a commonly used risk score (allergic reaction to the index sitting, sensitization measured by skin prick test and specific IgE, and specific IgG - maximal 8 points) for its predictability of forthcoming allergic reactions. 93 children with low scores (less than 7 points) experienced stings in field, 96% were save from severe systemic reactions. Of 119 children with high scores (greater than 6 points) receiving rush hyposensitization only 32% developed systemic reactions. We conclude that the score appropriately identifies individuals not to be hyposensitized, but that it overestimates the number of children with a need for hyposensitization. We therefore developed a diagnostic scheme including challenge stings to identify those children who really need hyposensitization.
authors.affiliation: Universitäts-Kinderklinik Freiburg, Bundesrepublik Deutschland.
authors.forename: J
authors.initials: J
authors.lastname: Forster
authors.forename: A
authors.initials: A
authors.lastname: Eckes
authors.forename: P
authors.initials: P
authors.lastname: Hauk
authors.forename: R
authors.initials: R
authors.lastname: Urbanek
mesh_terms: D000293:Adolescent; D001514:Bee Venoms / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis* / Q000276:immunology; D007299:Insect Bites and Stings / Q000276:immunology*; D012882:Skin Tests
chemical_list: D001514:Bee Venoms
vernacular_title: Spezielle Probleme der Insektengift-Allergie im Kindesalter.