title: An outbreak of aflatoxicosis in Angora rabbits.
abstract: An outbreak of aflatoxicosis in Angora rabbits involving a large number of rabbitries was investigated. Mortality was more in weaners than in adults. Affected animals showed anorexia, dullness and weight loss followed by jaundice in terminal stages. Death occurred within 3-4 d of the appearance of clinical signs. Livers were moderately to severely congested, icteric and were hard to cut. Gall bladders were distended and had inspissated bile. Liver sections showed degenerative changes of hepatic cells along with dilatation and engorgement of sinusoids. Bile ducts had mild to severe periportal fibrosis. Focal areas of pseudolobulation and regenerative foci were also predominant. The level of aflatoxin B1 in feed samples from various farms submitted at the time of the investigation varied from 90 to 540 ug aflatoxin B1/kg of feed. Withdrawal of feed and supplementary therapy resulted in gradual disappearance of signs and mortality.
authors.affiliation: Disease Investigation Laboratory, Indian Veterinary Research Institute, Regional Station Palampur.
authors.forename: L
authors.initials: L
authors.lastname: Krishna
authors.forename: R K
authors.initials: RK
authors.lastname: Dawra
authors.forename: J
authors.initials: J
authors.lastname: Vaid
authors.forename: V K
authors.initials: VK
authors.lastname: Gupta
mesh_terms: D000348:Aflatoxins / Q000032:analysis; D000367:Age Factors; D000821:Animal Feed / Q000032:analysis; D000822:Animal Husbandry; D000818:Animals; D056486:Chemical and Drug Induced Liver Injury; D004196:Disease Outbreaks / Q000706:statistics & numerical data / Q000662:veterinary*; D006331:Heart Diseases / Q000139:chemically induced / Q000662:veterinary; D007674:Kidney Diseases / Q000139:chemically induced / Q000662:veterinary; D008107:Liver Diseases / Q000662:veterinary; D015651:Mycotoxicosis / Q000453:epidemiology / Q000662:veterinary*; D011817:Rabbits; D000096702:Aflatoxin Poisoning
chemical_list: D000348:Aflatoxins