title: [Hemorrhagic shock and encephalopathy syndrome in infancy and childhood].
abstract: After a few days of prodromal illness with diarrhea and fever there was an abrupt onset of coma, seizures, severe shock, and hyperpyrexia in two infants; they than developed bleeding, pancytopenia, and impairment of liver and renal function. Both infants survived with major neurologic sequelae. The clinical symptoms and laboratory parameters were compatible with hemorrhagic shock and encephalopathy syndrome which was first described in 1983. The clinical course and biochemical features of this disease and its differential diagnoses are described, and etiology and pathogenesis are discussed. Furthermore it will be discussed, whether the hemorrhagic shock and encephalopathy syndrome is actually a "new" disease or just a new label for a known disorder.
authors.affiliation: Klinik für Pädiatrie, Medizinischen Universität zu Lübeck.
authors.forename: M
authors.initials: M
authors.lastname: Kirschstein
authors.forename: F
authors.initials: F
authors.lastname: Aksu
authors.forename: F
authors.initials: F
authors.lastname: Tegtmeyer
mesh_terms: D001925:Brain Damage, Chronic / Q000175:diagnosis / Q000628:therapy; D002543:Cerebral Hemorrhage / Q000175:diagnosis / Q000628:therapy; D003422:Critical Care; D003937:Diagnosis, Differential; D004660:Encephalitis / Q000175:diagnosis* / Q000628:therapy; D005260:Female; D006801:Humans; D007223:Infant; D008111:Liver Function Tests; D012771:Shock, Hemorrhagic / Q000175:diagnosis* / Q000628:therapy; D013577:Syndrome; D014057:Tomography, X-Ray Computed
vernacular_title: Hämorrhagisches Schock-und Enzephalopathiesyndrom im Säuglings- und Kindesalter.