Organization and transcription of canine (CAC)n sequences.
Twenty-nine canine DNA samples, including samples from 11 members of an autosomal recessive retinal degeneration pedigree, were fingerprinted with a (CAC)n probe using a chemiluminescent method. Sixteen polymorphic bands were identified in the two pedigrees. Nine polymorphic bands were scored in one pedigree; seven polymorphic bands were scored in the other pedigree. None were sex-linked. Hybridization of the (CAC)n probe to total and poly A+ RNAs from different canine tissues revealed a prominent polyadenylated message at 6 kb that was present in the retina, spleen, and kidney but not in the liver or heart.
Hershfield
B
B
Section of Medical Genetics, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010.
Inouye
L
L
Chader
G
G
Ripps
H
H
Aguirre
G
G
D000818:Animals; D001483:Base Sequence; D004247:DNA; D016172:DNA Fingerprinting; D004285:Dogs / Q000235:genetics*; D005260:Female; D008163:Luminescent Measurements; D008297:Male; D008969:Molecular Sequence Data; D015345:Oligonucleotide Probes; D010375:Pedigree; D011110:Polymorphism, Genetic; D012162:Retinal Degeneration / Q000235:genetics / Q000662:veterinary; D014158:Transcription, Genetic
D015345:Oligonucleotide Probes; D004247:DNA