[Comparative evaluation of the immunoenzyme test systems for HIV-1 and HIV-2 infections].
Comparative investigations of enzyme immunoassay systems for the diagnosis of HIV-infection were conducted in panels with HIV-1 and HIV-2-positive and negative samples. It has been shown that immunodiagnostic reagents produced by the firms "Abbott" (USA) and "Behring" (FRG) possess the highest sensitivity and specificity. It has been established that the test-systems for HIV-1 cannot identify HIV-2-positive samples due to the absence of cross-reactivity. To decrease the risk of HIV transmission through the blood it is recommended that immunodiagnostic tests for both virus types should be conducted in blood donors' screening.
Golosova
T V
TV
Tupoleva
T A
TA
Margolina
A N
AN
D015492:AIDS Serodiagnosis / Q000379:methods*; D005060:Europe; D005188:False Negative Reactions; D015483:HIV Antibodies / Q000032:analysis; D006679:HIV Seropositivity / Q000175:diagnosis; D015497:HIV-1 / Q000276:immunology; D015498:HIV-2 / Q000276:immunology; D006801:Humans; D007124:Immunoenzyme Techniques; D014481:United States
D015483:HIV Antibodies
Sravnitel'naia otsenka immunofermentnykh test-sistem dlia infektsiĭ VICh-1 i VICh-2.