title: Hyaluronic acid in a cardiac myxoma: a biochemical and histological analysis.
abstract: Cardiac myxoma is the most common primary tumor of the heart. This tumor has a gelatinous stroma that is thought to be composed of glycosaminoglycans, the classical acid mucopolysaccharide ground substance. We examined both biochemically and histologically the hyaluronic acid in a case of cardiac myxoma using a newly developed hyaluronic acid-binding protein probe. We observed that hyaluronic acid was localized in the amorphous stroma and occurred at levels 30 times that found in normal atrial septum.
authors.affiliation: Department of Surgery, University of California, San Francisco 94143.
authors.forename: M T
authors.initials: MT
authors.lastname: Longaker
authors.forename: E S
authors.initials: ES
authors.lastname: Chiu
authors.forename: B
authors.initials: B
authors.lastname: Hendin
authors.forename: W E
authors.initials: WE
authors.lastname: Finkbeiner
authors.forename: R
authors.initials: R
authors.lastname: Stern
mesh_terms: D006338:Heart Neoplasms / Q000737:chemistry*; D006801:Humans; D006820:Hyaluronic Acid / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D009232:Myxoma / Q000737:chemistry*
chemical_list: D006820:Hyaluronic Acid