title: Should all patients with malignant astrocytoma have postoperative radiotherapy?
abstract: A retrospective analysis was carried out on 96 patients with malignant astrocytoma treated during the period 1977--1986 to evaluate the contribution of postoperative radiation treatment to survival. In this material the initial Karnofsky performance score, age and extent of resection appeared to be prognostic factors, on the basis of which suggestions are given for selection of patients for radiotherapy.
authors.affiliation: Department of Clinical Oncology, University Medical Centre, Leiden, The Netherlands.
authors.forename: A
authors.initials: A
authors.lastname: Snijders-Keilholz
authors.forename: J H
authors.initials: JH
authors.lastname: Voormolen
authors.forename: J
authors.initials: J
authors.lastname: Hermans
authors.forename: G W
authors.initials: GW
authors.lastname: Padberg
authors.forename: J
authors.initials: J
authors.lastname: Davelaar
authors.forename: J W
authors.initials: JW
authors.lastname: Leer
mesh_terms: D000328:Adult; D001254:Astrocytoma / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000556:secondary; D001932:Brain Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality; D009367:Neoplasm Staging; D011788:Quality of Life; D011829:Radiation Dosage; D012189:Retrospective Studies; D015996:Survival Rate