Enhanced expression of protein kinase C gene caused by solar radiation.
Natural solar radiation (5 min of midday exposure in mid July, latitude 42 degrees N) induces protein kinase C mRNA almost two-fold in human epithelioid P3 cells in culture. This response is the same as that following tumor promotion by chemicals. The result indicates a possible role of promotion by solar UV radiation.
Peak
J G
JG
Biological and Medical Research Division, Argonne National Laboratory, IL 60439.
Woloschak
G E
GE
Peak
M J
MJ
D002460:Cell Line; D004848:Epithelium; D015870:Gene Expression / Q000528:radiation effects*; D006801:Humans; D011493:Protein Kinase C / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics / Q000528:radiation effects; D013472:Sunlight; D014466:Ultraviolet Rays
D012333:RNA, Messenger; D011493:Protein Kinase C