[Drug interactions of cyclosporine. Literature review].
The cyclosporine is widely used as an immuno-suppressive agent in association with others drugs. Its narrow therapeutic range requires frequent monitoring. We suggest a literature review of suspected or confirmed drug interactions. The classification is presented as: absorption interactions; pharmacokinetic interactions in antiinfectious, anticonvulsants, cardiovascular drugs, H2 antagonists agents, hormonotherapy; pharmacodynamic interactions associated to increased cyclosporine nephrotoxicity.
Bouquet
S
S
Laboratoire de Pharmacocinétique, CHRU la Milétrie, Poitiers.
Chapelle
G
G
Perault
M C
MC
Rochard
E
E
Vandel
B
B
D000818:Animals; D000890:Anti-Infective Agents / Q000378:metabolism; D002317:Cardiovascular Agents / Q000378:metabolism; D003524:Cyclosporins / Q000378:metabolism* / Q000494:pharmacology; D004347:Drug Interactions; D004357:Drug Synergism; D006801:Humans
D000890:Anti-Infective Agents; D002317:Cardiovascular Agents; D003524:Cyclosporins
Interactions médicamenteuses de la ciclosporine. Revue de littérature.