Glycohistochemical visualisation of mannose-binding lectins in the microvasculatures of brain and brain tumours.
Alpha-mannosylated albumins with three types of linkage between sugar and protein were compared. The results showed their histochemical binding to be sensitive to the nature of the linkage configuration. One configuration permitted visualisation of lectin losses from the tumour blood vessels, already known from biochemical analysis.
Debbage
P
P
Anatomical Institute, University of Munich.
Marguth
F
F
Gabius
H J
HJ
D001921:Brain / Q000098:blood supply* / Q000166:cytology / Q000378:metabolism; D001932:Brain Neoplasms / Q000098:blood supply* / Q000378:metabolism / Q000473:pathology; D005910:Glioma / Q000098:blood supply* / Q000378:metabolism / Q000473:pathology; D006651:Histocytochemistry / Q000379:methods; D006801:Humans; D037102:Lectins / Q000378:metabolism*; D008358:Mannose / Q000378:metabolism*; D008833:Microcirculation / Q000378:metabolism / Q000648:ultrastructure
D037102:Lectins; D008358:Mannose