Development of light dissemination in the rat lens after in vivo exposure to radiation in the 300-nm wavelength region.
The course of development of light dissemination was investigated for rat lenses exposed in vivo to 30 kJ/m2 ultraviolet radiation (UVR) in the 300-nm wavelength region. After an initial latency phase the light dissemination increases rapidly. At 72 h after the exposure to UVR, light dissemination almost reaches a maximum. An exponential model is proposed for the analysis of this pattern. Light dissemination also increases in lenses contralateral to exposed. This indicates that there may be a systemic response after exposure to UVR which can lead to cataract formation.
Söderberg
P G
PG
Department of Ophthalmology, Karolinska Institute, Stockholm, Sweden.
D000818:Animals; D002386:Cataract / Q000209:etiology; D007908:Lens, Crystalline / Q000528:radiation effects*; D008027:Light; D008297:Male; D008954:Models, Biological; D051381:Rats; D011919:Rats, Inbred Strains; D012542:Scattering, Radiation; D014466:Ultraviolet Rays / Q000009:adverse effects*