Prevalence of G-6-PD deficiency in a malaria endemic tribal area of Orissa (India).
A total of 207 men belonging to Bhuyan, Juanga and Munda tribes and 108 non-tribal residents of Banspal block area of Keonjhar district of Orissa were screened for glucose-6-phosphate dehydrogenase (G-6-PD) deficiency, abnormal haemoglobin and malaria parasite. In the tribal group, G-6-PD enzyme deficiency was observed in 13.52 per cent as compared to 3.70 per cent in non-tribals. No abnormal haemoglobin was detected in the studied population, while 15.87 per cent of individuals were positive for Plasmodium falciparum. An extremely weak association was observed between malaria and G-6-PD deficiency.
Chhotray
G P
GP
Department of Pathology, Regional Medical Research Centre (Indian Council of Medical Research), Bhubaneswar.
Ranjit
M R
MR
D000818:Animals; D005260:Female; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000453:epidemiology*; D006451:Hemoglobin, Sickle / Q000032:analysis; D006801:Humans; D007194:India; D008288:Malaria / Q000453:epidemiology*; D008297:Male; D010963:Plasmodium falciparum; D015995:Prevalence
D006451:Hemoglobin, Sickle