[Detoxification function of the liver and body resistance in patients with acute intestinal obstruction].
The authors studied the unspecific resistance of the organism according to the ratio of the formed elements of the blood, the detoxification function of the liver by the antipyrine test and evaluation of the acetylation capacity, as well as the leukocyte intoxication index in 42 patients with various types of acute ileus (obstructive, strangulation, dynamic). Ileus was found to reduce the unspecific resistance and the acetylation capacity of the patient's organism with the increased leukocyte intoxication index. In patients with obstructive ileus the antipyrine half-life was increased and was not normalized during treatment. The postoperative period in patients with a marked diminution of unspecific resistance and acetylation capacity of the organism with an increase in the leukocyte intoxication index and antipyrine half-life was characterized by an unfavourable course and the development of various purulent complications.
Razzakov
S M
SM
Krakovskiĭ
M E
ME
Ashirmetov
A Kh
AKh
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000983:Antipyrine / Q000493:pharmacokinetics*; D001711:Biotransformation / Q000502:physiology; D006801:Humans; D007108:Immune Tolerance / Q000502:physiology; D007415:Intestinal Obstruction / Q000276:immunology / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008875:Middle Aged
D000983:Antipyrine
Detoksikatsionnaia funktsiia pecheni i rezistentnost' organizma u bol'nykh s ostroĭ kishechnoĭ neprokhodimost'iu.