Comparative absorption of calcium from carbonate tablets, lactogluconate/carbonate effervescent tablet, and chloride solution.
Intestinal absorption of calcium from three different labelled calcium preparations (all containing 500 mg elemental calcium) was determined using the whole body retention and urinary excretion of 47Ca in 14 normal subjects. Chewable calcium carbonate tablets showed a significantly (p less than 0.05) better mean minimum absorption of calcium (25.6% in exp. I, 22.8% in exp. II) than calcium given in the form of a lactogluconate/carbonate effervescent tablet, (17%), but similar to calcium in a chloride solution (24.7%). The minimum calcium absorption varied from 85 to 128 mg. All the preparations were taken with standardized low calcium test meals.
Ekman
M
M
Dept. of Medicine, Karolinska Hospital, Stockholm, Sweden.
Reizenstein
P
P
Teigen
S W
SW
Rønneberg
R
R
D000328:Adult; D002118:Calcium / Q000493:pharmacokinetics*; D002119:Calcium Carbonate / Q000008:administration & dosage; D002122:Calcium Chloride / Q000008:administration & dosage; D004338:Drug Combinations; D005260:Female; D005942:Gluconates / Q000008:administration & dosage; D006801:Humans; D007408:Intestinal Absorption / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D012996:Solutions; D013607:Tablets
D004338:Drug Combinations; D005942:Gluconates; D012996:Solutions; D013607:Tablets; C041283:lactogluconic acid; D002119:Calcium Carbonate; D002122:Calcium Chloride; D002118:Calcium