Gynandroblastoma of the ovary having a typical morphological appearance: a case study.
A rare gynandroblastoma of the right ovary with a typical morphological appearance in a 65-year-old woman is reported. The tumor comprised both a granulosa cell element with a Call-Exner body and a Sertoli cell element. Pathologically, this case could be the most typical of all the world's established cases. Clinically, there were feminizing symptoms such as post-menopausal genital bleeding and endometrial cystic hyperplasia. Pre-operative serum hormonal assays indicated elevated levels of estrone, estradiol and testosterone, and low levels of gonadotropins. These returned to normal after surgery.
Yamada
Y
Y
Department of Gynecology, National Cancer Center Hospital, Tokyo.
Ohmi
K
K
Tsunematu
R
R
Yokota
H
H
Yamada
T
T
Tanemura
K
K
Sonoda
T
T
Kishi
K
K
Teshima
S
S
D000368:Aged; D005260:Female; D012739:Gonadal Steroid Hormones / Q000378:metabolism; D006801:Humans; D018309:Neoplasms, Gonadal Tissue / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D010051:Ovarian Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery
D012739:Gonadal Steroid Hormones