[Peripheral hepatic artery embolization: experimental study in dogs].
Peripheral hepatic artery embolization was induced in dogs by intra-arterial injection of cisplatin mixture. The result showed that development of hepatocellular damage and liver infarction was accompanied synchronously with impairment of the liver-function tests during 3-7 days after the embolization, and this impairment recovered gradually afterward. The emboli were 86 microns +/- 46 microns in diameter, and were mainly found in the hepatic micro-arteries. The presence of peripheral hepatic artery occlusion was considered effective in preventing the development of collateral circulation.
Yao
X H
XH
Department of Pathology, Zhejiang Provincial People's Hospital, Hangzhou.
D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D001663:Bilirubin / Q000097:blood; D002945:Cisplatin / Q000008:administration & dosage; D003097:Collateral Circulation; D004285:Dogs; D004621:Embolization, Therapeutic; D005260:Female; D006499:Hepatic Artery / Q000473:pathology; D008099:Liver / Q000473:pathology*; D008102:Liver Circulation; D008297:Male; D008863:Microspheres
D000410:Alanine Transaminase; D002945:Cisplatin; D001663:Bilirubin