title: A feasibility study of quantitative respirator fit testing by controlled negative pressure.
abstract: The feasibility of using a direct measure of respirator leakage flow rate as a quantitative index of respirator face seal fit has been explored through the use of a new controlled negative pressure method. The method is based on exhausting air from a temporarily sealed respirator facepiece at a rate sufficient to generate and then sustain a constant negative pressure inside the facepiece while the wearer holds his breath. The magnitude of the negative pressure is preselected to replicate the mean inspiratory pressure inside the mask during normal wear. With the air-purifying paths into the respirator temporarily blocked, measurement of the exhaust flow rate yields a synonymous measure of the leakage flow rate into the mask during inspiration under normal use conditions. The feasibility of using the new method to quantify respirator fit was assessed in a preliminary study that compared its performance with a quantitative fit test method based on the use of dichlorodifluoromethane as a challenge agent. Study data exhibit a high degree of correlation (r greater than 0.99) and no significant difference between the two methods over a range of controlled mask leakage rates. A major advantage of the new method is that a worker can be fit tested with his assigned respirator because the method does not require a destructive sampling probe. Other significant benefits compared to current methods used to quantify respirator fit appear to include (1) ease of test administration, (2) simplicity of test components, (3) lack of a potentially toxic challenge agent, (4) a straightforward calibration procedure, (5) multiple test capability, (6) immediacy of test results, and (7) field portability of the test system.
authors.affiliation: School of Health Related Professions, University of Arizona, Tucson 85719.
authors.forename: C D
authors.initials: CD
authors.lastname: Crutchfield
authors.forename: M P
authors.initials: MP
authors.lastname: Eroh
authors.forename: M D
authors.initials: MD
authors.lastname: Van Ert
mesh_terms: D000393:Air Pollutants / Q000032:analysis; D002138:Calibration; D005617:Chlorofluorocarbons, Methane / Q000032:analysis; D004784:Environmental Monitoring; D005069:Evaluation Studies as Topic; D005240:Feasibility Studies; D011312:Pressure; D012134:Respiratory Protective Devices
chemical_list: D000393:Air Pollutants; D005617:Chlorofluorocarbons, Methane; C007782:dichlorodifluoromethane