title: Sodium-23 MR imaging of the kidney in guinea pig at 2.1 T, following arterial, venous, and ureteral ligation.
abstract: In vivo 23Na magnetic resonance images of guinea pig kidney were obtained at 2.1 T using a spin-echo sequence with an echo time of 19 ms. The intact kidney showed a very strong signal intensity in the sodium image. The signal intensity of the kidney decreased to 55% after ligation of the renal artery together with the vein and the ureter. The total sodium content in the excised kidney after arterial occlusion, measured by flame photometry, was 24% higher than that in the intact kidney. The transverse relaxation time (T2) of the extracellular sodium in the isolated kidney decreased to one-third of that in the intact kidney. This shortening of T2 may be partly responsible for the decrease in the 23Na signal intensity from the kidney after arterial occlusion.
authors.affiliation: Department of Molecular Physiology, National Institute for Physiological Sciences, Aichi, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Maeda
authors.forename: Y
authors.initials: Y
authors.lastname: Seo
authors.forename: M
authors.initials: M
authors.lastname: Murakami
authors.forename: S
authors.initials: S
authors.lastname: Kuki
authors.forename: H
authors.initials: H
authors.lastname: Watari
authors.forename: S
authors.initials: S
authors.lastname: Iwasaki
authors.forename: H
authors.initials: H
authors.lastname: Uchida
mesh_terms: D000818:Animals; D005260:Female; D006168:Guinea Pigs; D007511:Ischemia / Q000175:diagnosis; D007668:Kidney / Q000033:anatomy & histology* / Q000098:blood supply; D008026:Ligation; D008279:Magnetic Resonance Imaging / Q000379:methods*; D012077:Renal Artery; D012082:Renal Veins; D012975:Sodium Isotopes; D014513:Ureter
chemical_list: D012975:Sodium Isotopes