Albuminamide: a novel peptide amide isolated from bovine serum.
During a systemic search for peptides that possess the C-terminal amide structure, a novel heptapeptide with isoleucine amide was isolated from bovine serum by sequential steps of reversed phase HPLC. Microsequence and amino acid analyses revealed the structure: Asp-Thr-His-Lys-Ser-Glu-Ile-NH2. Since this peptide has the identical sequence to N-terminal (1-7) fragment of bovine serum albumin (BSA), we have designated it albuminamide. The final HPLC step yielded 10 micrograms of homogeneous peptide preparation from 1 liter of bovine serum.
Takamatsu
K
K
Department of Physiology, Keio University School of Medicine, Tokyo, Japan.
Tatemoto
K
K
D000595:Amino Acid Sequence; D000818:Animals; D002417:Cattle; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000097:blood* / Q000737:chemistry
D009842:Oligopeptides; C069747:albuminamide