A girl treated with growth hormone presenting with neuromyopathy as first sign of acute lymphoblastic leukemia.
An 11-year-old girl being treated with DNA-recombinant growth hormone therapy presented with proximal limb weakness. Laboratory studies were negative. A few months later she presented with acute lymphoblastic leukemia (ALL). A diagnosis of carcinomatous neuromyopathy was made. After successful treatment of the leukemia the symptoms subsided and did not recur.
de Grauw
T J
TJ
Dept of Pediatrics, Free University Hospital, Amsterdam, The Netherlands.
Delemarre-van der Waal
H A
HA
Odink
R J
RJ
de Waal
F C
FC
D002648:Child; D004274:DNA, Recombinant / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D009468:Neuromuscular Diseases / Q000209:etiology*; D010907:Pituitary Hormones / Q000009:adverse effects / Q000627:therapeutic use*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000139:chemically induced / Q000150:complications*
D004274:DNA, Recombinant; D010907:Pituitary Hormones