title: Quantitative autoradiographic localization of [125I]alpha-bungarotoxin binding sites in the honeybee brain.
abstract: Binding sites for the nicotinic acetylcholine receptor antagonist, [125I]alpha-bungarotoxin, were localized in the honeybee brain by in vitro autoradiography. Highest binding site densities were localized in the suboesophageal ganglion, the optic tubercles, optic lobes medulla and lobula, antennal lobes, dorsal lobes and the alpha-lobes of the mushroom bodies. The distribution pattern of these putative nicotinic acetylcholine receptors suggests that acetylcholine is involved in several sensory pathways and in central information processing in the honeybee brain.
authors.affiliation: Department of Biology, Technical University of Berlin, F.R.G.
authors.forename: A
authors.initials: A
authors.lastname: Scheidler
authors.forename: P
authors.initials: P
authors.lastname: Kaulen
authors.forename: G
authors.initials: G
authors.lastname: Brüning
authors.forename: J
authors.initials: J
authors.lastname: Erber
mesh_terms: D000818:Animals; D001345:Autoradiography / Q000379:methods; D001516:Bees; D001665:Binding Sites; D001921:Brain / Q000378:metabolism*; D002038:Bungarotoxins / Q000378:metabolism; D007457:Iodine Radioisotopes; D009928:Organ Specificity; D011950:Receptors, Cholinergic / Q000378:metabolism*; D011978:Receptors, Nicotinic; D064569:alpha7 Nicotinic Acetylcholine Receptor
chemical_list: D002038:Bungarotoxins; D007457:Iodine Radioisotopes; D011950:Receptors, Cholinergic; D011978:Receptors, Nicotinic; D064569:alpha7 Nicotinic Acetylcholine Receptor