title: Truncal vagotomy reduces food and liquid intake in man.
abstract: Truncal vagotomy reduces food and liquid intake in laboratory animals but has not been studied in man. Seven (6F) morbidly obese patients kept 4-day dietary diaries with validation by urine nitrogen analysis before and 3 and 9 months after truncal vagotomy without drainage. Significant reductions in body weight were accompanied by reductions in self-reported total calorie intake from 2800 kcal/day to 1800 at 3 months and 2000 kcal/day at 9 months. The correlation between reported and validated protein intake was .72 (p less than 0.001) with a mean underreporting of protein intake by at least 27%. Macronutricant postoperative reductions in total volume and calorie density of liquid intake. Liquid calories were reduced by 47% at 3 months and 50% at 9 months and solid calories by 33% at 3 months and 27% at 9 months. It is concluded that truncal vagotomy reduces food and liquid intake in man preferentially through liquid reduction. These results have implications for surgical treatment of morbid obesity.
authors.affiliation: Department of Surgery, University of Goteborg, Sweden.
authors.forename: L
authors.initials: L
authors.lastname: Gortz
authors.forename: A C
authors.initials: AC
authors.lastname: Bjorkman
authors.forename: H
authors.initials: H
authors.lastname: Andersson
authors.forename: J G
authors.initials: JG
authors.lastname: Kral
mesh_terms: D000293:Adolescent; D000328:Adult; D001835:Body Weight / Q000502:physiology; D004326:Drinking / Q000502:physiology*; D004435:Eating / Q000502:physiology*; D002149:Energy Intake / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000503:physiopathology / Q000601:surgery*; D011183:Postoperative Complications / Q000503:physiopathology*; D015167:Vagotomy, Truncal; D014630:Vagus Nerve / Q000503:physiopathology*