[The effect of biologically active substances from the spleen on the content of somatotropic hormone in the rat hypophysis].
The influence of splenin, a "splenic protein-free extract", and splenectomy on the somatotropic hormone content in the rat pituitary were investigated. It was established that the concentration of this pituitary hormone was only decreased after "protein-free extract" administration. It was suggested that the detected effect was due to peptides incorporated in the preparation composition.
Korpachev
V V
VV
Shostak
I N
IN
D000818:Animals; D004305:Dose-Response Relationship, Drug; D013006:Growth Hormone / Q000032:analysis / Q000187:drug effects*; D008297:Male; D010902:Pituitary Gland / Q000737:chemistry / Q000187:drug effects*; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000502:physiology*; D013156:Splenectomy; D013946:Thymopoietins / Q000494:pharmacology; D014020:Tissue Extracts / Q000494:pharmacology
D013946:Thymopoietins; D014020:Tissue Extracts; C032841:thymopoietin III; D013006:Growth Hormone
Vliianie biologicheski aktivnykh veshchestv selezenki na soderzhanie somatotropnogo gormona v gipofize krys.