[The Bohr effect during an uncomplicated course of the early postoperative period in heart surgery patients].
48 patients have been examined in the early postoperative period after open heart surgery (25 patients after correction of acquired heart valve defects and 23 patients after aortocoronary bypass surgery on 2-6 coronary arteries). Gas exchange parameters, hemodynamics, hemoglobin, gases, acid-base balance were studied and P50 was determined with the Severinghaus blood gas analyzer. Using a multidimensional regression analysis, the regularities of P50 changes in uncomplicated postoperative period have been investigated (namely coefficients of temperature and Bohr's shifts of oxyhemoglobin dissociation curve have been studied). It has been shown that the main factors responsible for P50 changes in patients with uncomplicated postoperative period are Bohr's effect (i. e. the impact of pH and pCO2) and the body temperature. With pH and T changes, the coefficients were close to classical ones: -0.37, -0.42 and 0.035, respectively. In Bohr's effect the coefficient, as determined by multidimensional regression analysis, was not very reliable, which was due to its low value (about 0.001).
Riadovoĭ
G V
GV
Tutubalin
V N
VN
D006348:Cardiac Surgical Procedures; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010108:Oxyhemoglobins / Q000378:metabolism*; D011184:Postoperative Period
D010108:Oxyhemoglobins
Effekt Bora pri neoslozhnennom techenii rannego posleoperatsionnogo perioda u kardiokhirurgicheskikh bol'nykh.