title: [Cerebral blood flow scintigraphy using 99mTc-HM-PAO in the diagnosis of brain death].
abstract: In 9 patients with the clinical diagnosis of brain death, a HM-PAO-SPECT was performed to document the arrest of cerebral circulation. Besides brain-stem areflexia, negative apnea-test and an observation time of at least 12 hours neurophysiological examinations (EEG and evoked potentials) were performed. In 4 cases, an additional arterial digital subtraction angiography proved the arrest of cerebral circulation shown in SPECT. In 5 cases, there was cortical low activity still present in EEG with negative SPECT. HM-PAO-SPECT seems to be a reliable noninvasive radiological method in the determination of brain death. It is especially helpful in cases with persisting focal cortical EEG-activity.
authors.affiliation: Neurologischen Klinik, Universität Heidelberg, Mannheim, BRD.
authors.forename: P
authors.initials: P
authors.lastname: Berlit
authors.forename: E
authors.initials: E
authors.lastname: Wetzel
authors.forename: U
authors.initials: U
authors.lastname: Bethke
authors.forename: B
authors.initials: B
authors.lastname: Pohlmann-Eden
mesh_terms: D000293:Adolescent; D000328:Adult; D000465:Algorithms; D001926:Brain Death / Q000000981:diagnostic imaging*; D002648:Child; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime
vernacular_title: Hirnblutflussszintigraphie mit 99mTc-HM-PAO zur Diagnose des Hirntodes.