[Effect of hyperlipidemia and hypothyroidism on auditory evoked brain stem responses].
Temporary changes in audiometry have been reported in hypercholesterolaemia and in hypo- and hyperthyroidism. The purpose of the present prospective and controlled study was to record changes in conduction time of auditory brain-stem response (ABR) in patients with hyperlipidaemia and hypothyroidism before and after therapy over a period of 6 months. The acoustic evoked brain-stem response Jewett waves I-V were delayed in patients with hypercholesterolaemia, hypertrigliceridaemia and hypothyroidism in comparison with an age-matched control group. The changes in pure-tone threshold and brain-stem responses correlated with the degree of hyperlipidaemia or hypothyroidism. After treatment the brain-stem responses of hypothyroid patients tended to return to normal, and in a few cases normal pure-tone thresholds were achieved. Of the patients with hypercholesterolaemia and hypertrigliceridaemia, 28% had improvements in pure-tone thresholds, whereas no significant changes were found in the ABR following therapy.
Höhmann
D
D
Klinik und Poliklinik für Hals-, Nasen- und Ohrenkranke, Universität Würzburg.
Kahaly
G
G
Warzelhan
J
J
D001309:Auditory Threshold / Q000502:physiology; D001933:Brain Stem / Q000503:physiopathology*; D002784:Cholesterol / Q000097:blood; D004569:Electroencephalography / Q000295:instrumentation; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D006801:Humans; D006937:Hypercholesterolemia / Q000503:physiopathology; D006949:Hyperlipidemias / Q000503:physiopathology*; D007037:Hypothyroidism / Q000503:physiopathology*; D011930:Reaction Time / Q000502:physiology; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation
D002784:Cholesterol
Einfluss von Hyperlipidämien und Hypothyreosen auf die akustisch evozierten Hirnstammreizantworten.