title: [Therapy of penile viral condylomata with 0.5% podophyllotoxin].
abstract: Twenty male patients with penile warts (HPV induced papular and flat condylomata) attending the Venereal Disease Clinic at the Department of Dermatology, University di Pavia were treated with podophyllotoxin 0.5% in ethanol, self applied twice daily for 3 consecutive days, followed by 4 days without treatment. All the patients were cured after a maximum of 6 treatments; 10 patients (50%) were cured after 1 or 2 treatments. Three patients did not attend regularly at the control visits; 17 patients completed the study. Eight of the 17 patients (47.1%) showed recurrences of the warts; all of them were cured after successive podophyllotoxin treatments. Tolerance was good and only a few patients (30%) had mild adverse reactions. In conclusion podophyllotoxin 0.5% appeared to be safe and effective for the self treatment of genital warts.
authors.affiliation: Clinica Dermatologica, IRCCS Policlinico San Matteo, Università degli Studi di Pavia.
authors.forename: G
authors.initials: G
authors.lastname: Caresana
authors.forename: C
authors.initials: C
authors.lastname: Del Forno
mesh_terms: D000293:Adolescent; D000328:Adult; D003218:Condylomata Acuminata / Q000188:drug therapy*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010412:Penile Neoplasms / Q000188:drug therapy*; D011034:Podophyllotoxin / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors
chemical_list: D011034:Podophyllotoxin
vernacular_title: Terapia di condilomi virali penieni con podofillotossina allo 0.5%.