[Deoxyribonuclease activity in the blood serum of persons participating in liquidation of the effects of the accident at the Chernobyl nuclear power plant].
Deoxyribonuclease activity in blood serum was comparatively analyzed in 90 subjects who had been engaged in liquidation of consequences of the catastrophe at Chernobyl NPS in 1986, and in 55 normal donors. It was found that the mean value of deoxyribonuclease activity in the group of the liquidators was significantly lower as compared to that of donors. A stable decrease of activity of neutral deoxyribonuclease (DNAse I, pH 7.3) was detected in 18 and that of acid deoxyribonuclease (DNAse II) in 9 out of 90 subjects investigated. The anamnesis of most of the patients with lowered deoxyribonuclease activity has revealed transient leukopenia, decreased parameters of T-cellular immunity and phagocytic activity of neutrophils.
Moskalenko
I P
IP
Nikiforova
N A
NA
Kalmykova
I Ia
IIa
D000059:Accidents; D003851:Deoxyribonucleases / Q000097:blood / Q000172:deficiency / Q000528:radiation effects*; D006801:Humans; D009688:Nuclear Reactors; D011210:Power Plants; D011832:Radiation Injuries / Q000201:enzymology* / Q000209:etiology; D011847:Radioactive Fallout / Q000009:adverse effects*; D014455:Ukraine
D011847:Radioactive Fallout; D003851:Deoxyribonucleases
Aktivnost' dezoksiribonukleaz syvorotki krovi lits, uchastvova- iushchikh v likvidatsii posledstviĭ avarii na Chernobyl'skoĭ AES.