title: [General considerations on desensitization by the sublingual route].
abstract: A favourable action by a new method of therapy and in particular desensitization by the sub-lingual route is sometimes difficult to confirm. To make a sensible study requires a maximum of prior knowledge and this is not easy to acquire. How to select the patients? What method of administration is possible? What should be the dose adopted? What might be the secondary effects? Desensitization by the sub-lingual route seems to us to be a technique for the future. Impressions and thoughts on the new method route for desensitization must lead to controlled studies, very objective, which will confirm or invalidate it.
authors.affiliation: Laboratoire d'Immuno-Allergologie CHRU, Angers.
authors.forename: J
authors.initials: J
authors.lastname: Le Sellin
authors.forename: M
authors.initials: M
authors.lastname: Drouet
authors.forename: J C
authors.initials: JC
authors.lastname: Bonneau
authors.forename: A
authors.initials: A
authors.lastname: Sabbah
mesh_terms: D000286:Administration, Sublingual; D000485:Allergens / Q000008:administration & dosage* / Q000627:therapeutic use; D000818:Animals; D003888:Desensitization, Immunologic / Q000379:methods*; D005069:Evaluation Studies as Topic; D006801:Humans; D008925:Mites / Q000276:immunology; D011058:Pollen / Q000276:immunology
chemical_list: D000485:Allergens
vernacular_title: Considérations générales à propos de la désensibilisation par voie sublinguale.