title: [Quadrantectomy and tumorectomy followed by radiotherapy in early tumors of the breast].
abstract: The authors examined 235 patients with early breast cancer treated by radiotherapy after conservative surgery during a 10-year period (1974-1984). Disease-free survival and incidence of local recurrences, in agreement with the data reported in literature, did not differ from those of patients with early breast cancer treated with radical surgery. As for local recurrences in the breast only (7/235), a slightly significant difference was observed in favor of quadrantectomy (3/62 for tumorectomy versus 4/173 for quadrantectomy). On the contrary, a significant difference was observed in the breast recurrence rate of premenopausal (5/7) and postmenopausal women (2/7). Complications occurred in 7.2% of the cases. Satisfactory esthetic results were generally obtained, with 78% good and excellent results. Doses greater than 50 Gy to the whole breast and irradiation of the axilla both worsened the esthetic results and increased complication rate. Chemotherapy does not worsen the esthetic results, while that is often the case when the removed volume is excessive in comparison to the whole breast volume.
authors.affiliation: Divisione di Radioterapia e Oncologia, Ospedali Riuniti, Bergamo.
authors.forename: U
authors.initials: U
authors.lastname: Felci
authors.forename: A
authors.initials: A
authors.lastname: Personeni
authors.forename: L
authors.initials: L
authors.lastname: Pompei
authors.forename: R
authors.initials: R
authors.lastname: Guzzetti
authors.forename: A
authors.initials: A
authors.lastname: Agazzi
authors.forename: A
authors.initials: A
authors.lastname: Quadri
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D004954:Esthetics; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D011879:Radiotherapy Dosage; D013997:Time Factors
vernacular_title: Quadrantectomia e tumorectomia seguita da radioterapia nei tumori iniziali della mammella.