title: [A pharmacodynamic investigation of the effect of polyholozidic substances extracted from Plantago sp. on the digestive tract].
abstract: From the leaves and seeds of some Plantago species (Plantago major, media, lanceolata) the polyholozidic fraction was separated. A statistically significant gastroprotective action was found both in the case of the polyholozide obtained from seeds and leaves in two experimental models. At higher doses a laxative action was also obtained.
authors.affiliation: Facultatea de farmacie, Disciplina de farmacodinamie, Institutul de Medicină şi Farmacie Iaşi.
authors.forename: A
authors.initials: A
authors.lastname: Hriscu
authors.forename: U
authors.initials: U
authors.lastname: Stănescu
authors.forename: A
authors.initials: A
authors.lastname: Ionescu
authors.forename: A
authors.initials: A
authors.lastname: Verbuţă
mesh_terms: D000818:Animals; D000897:Anti-Ulcer Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001241:Aspirin; D002400:Cathartics / Q000494:pharmacology* / Q000627:therapeutic use; D004353:Drug Evaluation, Preclinical; D000431:Ethanol; D005769:Gastrointestinal Motility / Q000187:drug effects; D005772:Gastrointestinal Transit / Q000187:drug effects; D007213:Indomethacin / Q000627:therapeutic use; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use; D010943:Plantago; D010946:Plants, Medicinal; D051381:Rats; D013276:Stomach Ulcer / Q000139:chemically induced / Q000188:drug therapy
chemical_list: D000897:Anti-Ulcer Agents; D002400:Cathartics; D010936:Plant Extracts; D000431:Ethanol; D001241:Aspirin; D007213:Indomethacin
vernacular_title: Investigarea farmacodinamică a influenţei substanţelor poliholozidice extrase din Plantago sp. asupra tractului digestiv.