title: [Investigation of a transfusion contaminated by HTLV-I virus].
abstract: In front of the successive development of an HTLV-I seroconversion and a neuromyelopathy in a French Caucasian following a cardiac transplantation, an ascendant epidemiologic investigation must be manage to search a risk factor or a possible blood donor contaminated with HTLV-I virus. We selected an HTLV-I seropositive donor whose RBC participated to the patient's transfusion. This woman from Martinique island was a regular donor in our blood center and a second investigation was initiated to examine the patients transfused with the blood products issued from her previous donation. Nine were identified and controlled among them a patient who has received a RBC was found HTLV-I seropositive. An evaluation of the infectivity of the different blood products according to their type and specificity has been done. These data confirm that transmission of the HTLV-I is possible through donation of healthy seropositive donor and can induce the development of associated pathology, and prove the importance of screening blood donors for HTLV-I antibodies.
authors.affiliation: CTS Pitié-Salpêtrière, Paris.
authors.forename: C
authors.initials: C
authors.lastname: Fretz
authors.forename: D
authors.initials: D
authors.lastname: Jaulmes
authors.forename: A
authors.initials: A
authors.lastname: Nicod
authors.forename: G
authors.initials: G
authors.lastname: Jourdan
authors.forename: O
authors.initials: O
authors.lastname: Gout
authors.forename: A
authors.initials: A
authors.lastname: Gessain
authors.forename: A M
authors.initials: AM
authors.lastname: Jullien
authors.forename: J C
authors.initials: JC
authors.lastname: Gluckman
authors.forename: G
authors.initials: G
authors.lastname: de Thé
authors.forename: J J
authors.initials: JJ
authors.lastname: Fournel
mesh_terms: D000328:Adult; D001782:Blood Donors; D017707:Erythrocyte Transfusion; D015490:HTLV-I Infections / Q000635:transmission*; D016027:Heart Transplantation; D006801:Humans; D017713:Platelet Transfusion; D012307:Risk Factors; D065227:Transfusion Reaction
vernacular_title: Enquête à propos d'une contamination transfusionnelle par le virus HTLV-I.