title: Prostaglandin F2 alpha stimulates gluconeogenesis in the perfused rat liver and this effect is blunted in livers from endotoxin infused rats.
abstract: Prostaglandin F2 alpha stimulates gluconeogenesis from lactate plus pyruvate in perfused rat livers. Continuous endotoxin infusion for 30 h in vivo prior to F2 alpha stimulation blunts this effect.
authors.affiliation: Department of Physiology, Louisiana State University Medical Center, New Orleans 70112.
authors.forename: J A
authors.initials: JA
authors.lastname: Spitzer
authors.forename: I V
authors.initials: IV
authors.lastname: Deaciuc
mesh_terms: D000818:Animals; D015237:Dinoprost / Q000494:pharmacology*; D004731:Endotoxins / Q000494:pharmacology*; D004926:Escherichia coli; D005943:Gluconeogenesis / Q000187:drug effects*; D007700:Kinetics; D007773:Lactates / Q000378:metabolism; D019344:Lactic Acid; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D011773:Pyruvates / Q000378:metabolism; D019289:Pyruvic Acid; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D004731:Endotoxins; D007773:Lactates; D011773:Pyruvates; D019344:Lactic Acid; D019289:Pyruvic Acid; D015237:Dinoprost