Oral neostigmine and lymphatic absorption in a myasthenia gravis patient on continuous ambulatory peritoneal dialysis (CAPD).
The effects of oral neostigmine on peritoneal lymph absorption and transcapillary and net ultrafiltration were studied in a myasthenia gravis patient on continuous ambulatory peritoneal dialysis (CAPD). Oral neostigmine decreased lymphatic absorption, but only up to a threshold dose. The effect on net ultrafiltration however was nullified to some extent by a concurrent decrease in cumulative transcapillary ultrafiltration.
Chan
P C
PC
Department of Medicine, University of Hong Kong.
Tam
S C
SC
Cheng
I K
IK
D000284:Administration, Oral; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D008208:Lymphatic System / Q000187:drug effects / Q000378:metabolism*; D009157:Myasthenia Gravis / Q000188:drug therapy / Q000378:metabolism*; D009388:Neostigmine / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D010531:Peritoneal Dialysis, Continuous Ambulatory
D009388:Neostigmine