title: [Clinical study on total intravenous anesthesia with droperidol, fentanyl and ketamine--5. An anesthetic experience of a pediatric patient with severe epilepsy].
abstract: A 6-year-old girl with severe epilepsy received an orthopedic surgery of the right hand under new total intravenous anesthesia with droperidol, fentanyl and ketamine. For the induction of anesthesia, droperidol 0.25 mg.kg-1, fentanyl 5.0 micrograms.kg-1 and ketamine 2.0 mg.kg-1 was administered intravenously. She was intubated and ventilated manually throughout the operative procedure to maintain the end tidal CO2 between 4.5 and 5.5%. For the maintenance of anesthesia, ketamine was given continuously at a rate of 2.0 mg.kg-1.hr-1. Intraoperative muscle relaxation was obtained with vecuronium bromide. The patient recovered from anesthesia uneventfully. The total doses of droperidol, fentanyl, ketamine and vecuronium were 8.75 mg, 1.0 mg, 210 mg and 7.5 mg, respectively. Neither epileptic seizure, nor any other adverse effects with anesthetics was observed during and after anesthesia and surgery. We conclude that this method of anesthesia for epileptic patients may deserve further detailed study.
authors.affiliation: Department of Anesthesiology, University of Hirosaki School of Medicine.
authors.forename: H
authors.initials: H
authors.lastname: Koh
authors.forename: H
authors.initials: H
authors.lastname: Takagi
authors.forename: I
authors.initials: I
authors.lastname: Araki
authors.forename: S
authors.initials: S
authors.lastname: Shirasaki
authors.forename: H
authors.initials: H
authors.lastname: Ishihara
authors.forename: A
authors.initials: A
authors.lastname: Matsuki
mesh_terms: D000771:Anesthesia, Intravenous; D002648:Child; D004329:Droperidol; D004827:Epilepsy / Q000150:complications*; D005260:Female; D005283:Fentanyl; D006801:Humans; D007649:Ketamine; D009985:Orthopedics
chemical_list: D007649:Ketamine; D004329:Droperidol; D005283:Fentanyl