title: Design and discovery in the development of long-acting renin inhibitors.
authors.affiliation: Merck Sharp & Dohme Research Laboratories, West Point, PA 19486.
authors.forename: D F
authors.initials: DF
authors.lastname: Veber
authors.forename: L S
authors.initials: LS
authors.lastname: Payne
authors.forename: P D
authors.initials: PD
authors.lastname: Williams
authors.forename: D S
authors.initials: DS
authors.lastname: Perlow
authors.forename: G F
authors.initials: GF
authors.lastname: Lundell
authors.forename: N P
authors.initials: NP
authors.lastname: Gould
authors.forename: P K
authors.initials: PK
authors.lastname: Siegl
authors.forename: C S
authors.initials: CS
authors.lastname: Sweet
authors.forename: R M
authors.initials: RM
authors.lastname: Freidinger
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001682:Biological Availability; D015195:Drug Design; D008253:Macaca mulatta; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000737:chemistry / Q000493:pharmacokinetics / Q000494:pharmacology; D013329:Structure-Activity Relationship; D000092502:Renin Inhibitors
chemical_list: D009842:Oligopeptides; D000092502:Renin Inhibitors; C041553:renin inhibitory peptide, statine; C051529:renin inhibitory peptide, 4-amino-5-cyclohexyl-3-hydroxypentanoic acid