title: Hemodynamic and scintigraphic improvement after steroid therapy in a case with acute eosinophilic heart disease.
abstract: A 70-year-old woman with active hypereosinophilic myocarditis presented with high fever and heart failure. Repeated right ventricular endomyocardial biopsies and 201-T1 myocardial scans before and after steroid therapy suggested that this treatment reversed the cardiac injury. Patients with hypereosinophilia may die from complications of eosinophilic infiltration and fibrosis in target organs, especially the heart. The findings in this patient suggest that steroids have benefit in this disease, at least in the short term.
authors.affiliation: Department of Cardiology, Tokyo Women's Medical College, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Uetsuka
authors.forename: S
authors.initials: S
authors.lastname: Kasahara
authors.forename: N
authors.initials: N
authors.lastname: Tanaka
authors.forename: M
authors.initials: M
authors.lastname: Sekiguchi
authors.forename: M
authors.initials: M
authors.lastname: Hiroe
authors.forename: Z X
authors.initials: ZX
authors.lastname: Yu
authors.forename: S
authors.initials: S
authors.lastname: Hosoda
mesh_terms: D000208:Acute Disease; D000368:Aged; D004802:Eosinophilia / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D005260:Female; D005334:Fever / Q000209:etiology; D006333:Heart Failure / Q000209:etiology; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D009205:Myocarditis / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D011239:Prednisolone / Q000627:therapeutic use*; D011877:Radionuclide Imaging; D013794:Thallium Radioisotopes
chemical_list: D013794:Thallium Radioisotopes; D011239:Prednisolone