Polymorphisms of the regulators of complement activation gene cluster.
The regulators of complement activation (RCA) constitute a tightly linked gene family that controls the activity of the complement system. Genetic polymorphisms have been reported for all of RCA genes at the DNA, RNA and/or protein levels. In addition, multiple RNA and/or protein products have been observed for most of these genes. These polymorphisms and variants are instrumental in the study of the structure, evolution and function of the RCA family.
Hourcade
D
D
Howard Hughes Medical Institute Laboratories, Department of Medicine, Washington University, St. Louis, Mo.
Post
T W
TW
Holers
V M
VM
Lublin
D M
DM
Atkinson
J P
JP
D000595:Amino Acid Sequence; D005075:Biological Evolution; D003167:Complement Activation / Q000235:genetics*; D005809:Genes, Regulator; D008040:Genetic Linkage; D014644:Genetic Variation; D006801:Humans; D008969:Molecular Sequence Data; D005810:Multigene Family; D011110:Polymorphism, Genetic