[Evaluation of the effect of picotamide on platelet function in diabetic subjects].
In this study the Authors verify the results of Picotamide on platelet aggregation in diabetic subjects. The results suggest that Picotamide has no influence on insulin or oral treatment of diabetic subjects. However, it is certain that platelet aggregation by ADP or collagen decreases due to the effect on thromboxane probably because of the limitation of platelet receptors.
Carleo
R
R
Mal. del Ricambio e Nutrizione Clinica Ospedale San Gennaro, Napoli.
Veno
L
L
Fuccio
F
F
Bonavita
M
M
De Matteo
A
A
Gallo
M
M
Gatti
A
A
Gobbo
M
M
Nocerino
L
L
D000244:Adenosine Diphosphate / Q000037:antagonists & inhibitors / Q000494:pharmacology; D000368:Aged; D001792:Blood Platelets / Q000187:drug effects; D003094:Collagen / Q000037:antagonists & inhibitors / Q000494:pharmacology; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010795:Phthalic Acids / Q000494:pharmacology*; D010974:Platelet Aggregation / Q000187:drug effects*; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology*; D013930:Thromboxane-A Synthase / Q000037:antagonists & inhibitors
D010795:Phthalic Acids; D010975:Platelet Aggregation Inhibitors; D000244:Adenosine Diphosphate; C011581:picotamide; D003094:Collagen; D013930:Thromboxane-A Synthase
Valutazione degli effetti della picotamide sulla funzione piastrinica in soggetti diabetici.