title: Diacetyl-splenopentin (BCH 069) did not affect the concentrations of various hormones in men.
abstract: We investigated the effect of BCH 069 (similar structure as thymopentin) on concentrations of hormones of the hypophysis, adrenals, gonads and thyroid glands in men after a therapy period of 4 or 6 weeks. No significant effects of BCH 069 three times weekly 50 mg s.c. for 4 weeks or i.v. for 6 weeks on serum concentrations of prolactin, LH, TSH, cortisol, testosterone, progesterone, estradiol and ETR were observed.
authors.affiliation: Institute of Clinical Immunology, Friedrich Schiller University Jena/GDR.
authors.forename: H U
authors.initials: HU
authors.lastname: Simon
authors.forename: H
authors.initials: H
authors.lastname: Lauterbach
authors.forename: A
authors.initials: A
authors.lastname: Börner
authors.forename: S
authors.initials: S
authors.lastname: Wachtel
mesh_terms: D000328:Adult; D004958:Estradiol / Q000097:blood; D006728:Hormones / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D009842:Oligopeptides / Q000494:pharmacology*; D010446:Peptide Fragments / Q000494:pharmacology*; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood; D013739:Testosterone / Q000097:blood; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
chemical_list: C064311:BCH 069; D006728:Hormones; D009842:Oligopeptides; D010446:Peptide Fragments; D013739:Testosterone; D011374:Progesterone; D004958:Estradiol; D011388:Prolactin; D007986:Luteinizing Hormone; D013972:Thyrotropin; D013974:Thyroxine; D006854:Hydrocortisone