Synthesis of disaccharide methyl glycosides related to the polysaccharide from Klebsiella serotype 40 and a study of their inhibition in the precipitin reaction.
The methyl glycosides of alpha-D-Manp-(1----4)-alpha-L-Rhap (3), alpha-L-Rhap-(1----3)-beta-D-Galp (4), beta-L-Rhap-(1----3)-beta-D-Galp (5), beta-D-Galp-(1----2)-alpha-L-Rhap (6), and beta-D-GlcpA-(1----2)-alpha-L-Rhap (7) have been synthesised and their inhibition reactions in the Klebsiella serotype 40 immune system have been studied. The results obtained accord with only one of two structures proposed for the repeating unit of the K40 antigen.
Maddali
U B
UB
Department of Biological Chemistry, Indian Association for the Cultivation of Science, Calcutta.
Ray
A K
AK
Roy
N
N
D002240:Carbohydrate Sequence; D004187:Disaccharides / Q000138:chemical synthesis* / Q000276:immunology; D006027:Glycosides / Q000138:chemical synthesis* / Q000276:immunology; D007709:Klebsiella / Q000276:immunology*; D008969:Molecular Sequence Data; D015394:Molecular Structure; D011135:Polysaccharides, Bacterial / Q000138:chemical synthesis* / Q000276:immunology; D011233:Precipitin Tests; D012703:Serotyping
D004187:Disaccharides; D006027:Glycosides; D011135:Polysaccharides, Bacterial