[The role of lymphatic collector in the spreading infections in peritonitis].
The article generalizes the result of experimental study of the features of hemolymphodynamics, toxic properties of biological body fluids, and microbiological findings in peritonitis. Experiments were conducted on 24 dogs. The development of the pyogenic process was visually studied. For this purpose the opened abdominal cavity was placed in a specially constructed transparent chamber in which a temperature of 37 /*C was maintained. Portal blood flow intensified and lymph production in the abdominal cavity reduced in the initial phase of peritonitis. Later lymph production increased while the portal blood flow decreased. The purulent process may develop according to two variants. In the first variant the functional activity of the liver is maintained and its toxic products and microorganisms are detoxified; the second variant the detoxification function of the liver is disturbed, the bacteria penetrate the peripheral blood, the production and flow of lymph in the thoracic duct increase sharply. The efficacy of external drainage of the duct and lymphosorption is much higher in the second variant of peritonitis development than in the first variant.
Korotaev
G M
GM
Sheprinskiĭ
P E
PE
Osmokesku
K I
KI
D000818:Animals; D001783:Blood Flow Velocity; D004285:Dogs; D004322:Drainage; D005260:Female; D006439:Hemodynamics; D008208:Lymphatic System / Q000382:microbiology / Q000503:physiopathology*; D008297:Male; D010538:Peritonitis / Q000382:microbiology / Q000503:physiopathology* / Q000628:therapy; D006435:Renal Dialysis; D013897:Thoracic Duct / Q000601:surgery
Rol' limfaticheskogo kollektora v rasprostranenii infektsii pri peritonite.