[The importance of the state of the oxygen balance in the early period following severe mechanical trauma in the pathogenesis of the shock lung syndrome].
To elucidate the role of oxygen balance disturbances in the pathogenesis of shock lung syndrome (SLS) central hemodynamic parameters, arterial and mixed venous blood content, O2 transport (TO2) and consumption (VO2), TO2 reserve have been studied in 95 patients after trauma. Two groups of patients have been identified: group I--control (n = 48); and group II--patients with SLS (n = 47). Significant differences in central hemodynamics and oxygen balance between the groups before the manifestation of SLS symptoms were lower values of the cardiac output, TO2, VO2 and TO2 reserve in patients of group II. If, on the first day after trauma, there was hyperdynamic type of circulation and 40-50% increased (as compared to the physiological norm) VO2 in combination with sufficient TO2 reserve (about 100 ml/(min.m2) the likelihood of SLS onset was considerably reduced.
Vasilenko
N I
NI
Edeleva
N V
NV
D000293:Adolescent; D000328:Adult; D000368:Aged; D006801:Humans; D008875:Middle Aged; D010101:Oxygen Consumption / Q000502:physiology*; D012128:Respiratory Distress Syndrome / Q000209:etiology* / Q000503:physiopathology; D014947:Wounds and Injuries / Q000503:physiopathology*
Znachenie sostoianiia kislorodnogo balansa v rannie sroki posle tiazheloĭ mekhanicheskoĭ travmy v patogeneze razvitiia sindroma shokovogo legkogo.