title: Clinical course after mitral valve replacement.
abstract: Two hundred and fifty patients underwent mitral valve replacement for rheumatic valvular disease during a 9-year period from January 1979 to December 1987. A maximum period of follow-up of 10 years and minimum of 1 year was achieved with a mean duration of 4.4 years. The follow-up covered 921 out of a possible 1006 patient-years and was 91.5 per cent complete. Of the patients, 58 (23.2%) were in class II, 145 (58%) were in class III and 47 (18.8%) belonged to class IV. The early mortality for patients in Class II, III and IV was 8.6 per cent, 15.8 per cent and 31.9 per cent respectively and the 3, 5 and 10 years actuarial survival rates for the entire group were 93 per cent, 87 per cent and 70 per cent. The event-free survival rates at the same intervals were 77 per cent, 63 per cent and 57 per cent respectively. Late deaths occurred in 18 (9.5%) of the patients. Twelve of these (66.6%) could be directly ascribed to a valve-related cause.
authors.affiliation: Sree Chitra Tirunal Institute for Medical Sciences, Trivandrum.
authors.forename: S
authors.initials: S
authors.lastname: Rao
authors.forename: V M
authors.initials: VM
authors.lastname: Kurian
authors.forename: M
authors.initials: M
authors.lastname: Ghosh
authors.forename: R
authors.initials: R
authors.lastname: Sankarkumar
authors.forename: M P
authors.initials: MP
authors.lastname: Mohansingh
authors.forename: M S
authors.initials: MS
authors.lastname: Valiathan
mesh_terms: D002675:Child, Preschool; D005260:Female; D006349:Heart Valve Diseases / Q000209:etiology / Q000401:mortality / Q000601:surgery; D006350:Heart Valve Prosthesis / Q000009:adverse effects / Q000401:mortality; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D012214:Rheumatic Heart Disease / Q000150:complications / Q000401:mortality / Q000601:surgery*; D015996:Survival Rate; D013927:Thrombosis / Q000209:etiology; D013997:Time Factors