title: Disulfiram inhibits the in vitro growth of methicillin-resistant staphylococcus aureus.
abstract: Several antibiotics have disulfiram-like effects; we evaluated disulfiram for its antibiotic-like effects. Disulfiram inhibited the in vitro growth of methicillin-resistant Staphylococcus aureus, with an MIC of 1.33 micrograms/ml, but was not effective against members of the family Enterobacteriaceae or Pseudomonas species.
authors.affiliation: Department of Medicine, St. Vincent's Medical Center of Richmond, Staten Island, New York 10310.
authors.forename: M
authors.initials: M
authors.lastname: Phillips
authors.forename: G
authors.initials: G
authors.lastname: Malloy
authors.forename: D
authors.initials: D
authors.lastname: Nedunchezian
authors.forename: A
authors.initials: A
authors.lastname: Lukrec
authors.forename: R G
authors.initials: RG
authors.lastname: Howard
mesh_terms: D004221:Disulfiram / Q000494:pharmacology*; D004755:Enterobacteriaceae / Q000187:drug effects; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D011549:Pseudomonas / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000254:growth & development
chemical_list: D004221:Disulfiram