Seroprevalence and clinical manifestations of HIV-1 infection in Kananga, Zaire.
The objective of this study was to ascertain the seroprevalence and clinical manifestations of HIV-1 infection in Kananga, Zaire, in 1988. In the city of Kananga (population 300,000), eight out of 258 (3.1%) consecutive, asymptomatic, prenatal patients were seropositive. Of 452 consecutive blood donors at our institution, eight (1.8%) were seropositive. Sixty per cent of 299 consecutive, seropositive, clinically ill adults presented with chronic diarrhea, fever or weight loss (Centers for Disease Control group IVA). The male-to-female ratio of symptomatic, seropositive patients was 1:1.5. Women who indicated on a socioeconomic questionnaire that they engaged in 'commerce' (meaning possibly that they were petty traders, wholesale brokers, or prostitutes) were more often HIV-seropositive than women who did not engage in 'commerce' (P less than 0.001).
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Institut Médical Chrétien du Kasai, Kanaga, Zaire.
D000293:Adolescent; D000328:Adult; D001782:Blood Donors; D015023:Democratic Republic of the Congo / Q000453:epidemiology; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000503:physiopathology*; D015528:HIV Seroprevalence; D015497:HIV-1; D006801:Humans; D008297:Male; D011247:Pregnancy