title: [Tramal in the treatment of acute and chronic pain syndromes in cancer patients].
abstract: The study of 65 cancer patients has demonstrated the advantages and disadvantages of tramal as an agent used for the relief of acute and chronic pain syndrome. In 18 patients tramal was used in postoperative analgesia, in 17 patients it was used for the treatment of chronic pain syndrome. It has been shown that in the postoperative period tramal has no noticeable advantages over promedol. However, tramal had definite advantages over other opiate agonists when used for the treatment of chronic pain syndrome in incurable cancer patients. Thus, the data obtained show that tramal, a synthetic analgesic of a new generation, has no dangerous side effects, is effective in a convenient, non-invasive drug form, interacts well with non-narcotic and supplementary agents and causes no clinical signs of drug tolerance or addiction in prolonged application.
authors.forename: N A
authors.initials: NA
authors.lastname: Osipova
authors.forename: G A
authors.initials: GA
authors.lastname: Novikov
authors.forename: G R
authors.initials: GR
authors.lastname: Ziai
authors.forename: Z L
authors.initials: ZL
authors.lastname: Mel'nikova
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000503:physiopathology*; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D010149:Postoperative Pain / Q000188:drug therapy*; D014147:Tramadol / Q000627:therapeutic use*
chemical_list: D014147:Tramadol
vernacular_title: Tramal v lechenii ostrogo i khronicheskogo bolevogo sindroma u onkologicheskikh bol'nykh.