title: Erosion and perforation of a cusp by nodular calcification: an unusual cause of insufficiency in a congenital bicuspid aortic valve.
abstract: Aortic valve insufficiency may occur in a number of backgrounds. A unique etiology is illustrated in a 53-year-old man with terminal cardiac failure due to ischemic heart and aortic valvular disease. Nodular calcification complicated a congenital bicuspid valve and caused erosion through a valve cusp, producing a chronic cusp defect and valvular insufficiency.
authors.affiliation: Department of Pathology, University of Ottawa, Ontario.
authors.forename: V M
authors.initials: VM
authors.lastname: Walley
authors.forename: M D
authors.initials: MD
authors.lastname: Black
mesh_terms: D001021:Aortic Valve / Q000002:abnormalities* / Q000473:pathology; D001022:Aortic Valve Insufficiency / Q000209:etiology* / Q000473:pathology; D002114:Calcinosis / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged