title: 5-Fluorouracil cardiotoxicity: a critical review.
abstract: 5-Fluorouracil is a commonly administered chemotherapy agent that has infrequently been associated with cardiotoxicity. This review highlights the clinical features of this syndrome as described in reports from the medical literature. Clinical and laboratory evidence supporting proposed underlying mechanisms are reviewed.
authors.affiliation: Department of Medicine, Pritzker School of Medicine, University of Chicago.
authors.forename: W J
authors.initials: WJ
authors.lastname: Gradishar
authors.forename: E E
authors.initials: EE
authors.lastname: Vokes
mesh_terms: D000818:Animals; D005472:Fluorouracil / Q000009:adverse effects*; D006331:Heart Diseases / Q000139:chemically induced* / Q000453:epidemiology; D006801:Humans; D015994:Incidence
chemical_list: D005472:Fluorouracil