title: Inhibitory effect of cis-dehydromatricaria ester isolated from Solidago altissima on the growth of mammalian cells.
abstract: A cell growth inhibitory substance was isolated from Solidago altissima, which is known as a naturalized weed. The data of infrared spectrum, proton and carbon-13 nuclear magnetic resonance spectrum, and mass spectrum were identical with those of cis-dehydromatricaria ester. The compound inhibited both tumor and normal mammalian cells.
authors.affiliation: Hospital Pharmacy, Saga Medical School, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Matsunaga
authors.forename: M
authors.initials: M
authors.lastname: Katano
authors.forename: M
authors.initials: M
authors.lastname: Tasaki
authors.forename: H
authors.initials: H
authors.lastname: Yamamoto
authors.forename: M
authors.initials: M
authors.lastname: Mori
authors.forename: K
authors.initials: K
authors.lastname: Takata
mesh_terms: D000480:Alkynes / Q000302:isolation & purification / Q000494:pharmacology*; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D005231:Fatty Acids, Unsaturated / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D051379:Mice; D010946:Plants, Medicinal / Q000032:analysis*; D053279:Polyynes; D014407:Tumor Cells, Cultured / Q000187:drug effects* / Q000473:pathology
chemical_list: D000480:Alkynes; D000972:Antineoplastic Agents, Phytogenic; D005231:Fatty Acids, Unsaturated; D053279:Polyynes; C044104:dehydromatricaria methyl ester