Epithelioid angiosarcoma of the adrenal gland associated with chronic arsenical intoxication?
Epithelioid angiosarcoma is a rare tumor quite recently described. There is no accurate epidemiological study of this tumor. Among the internal organs, the liver is the one most frequently affected with angiosarcoma while there is no reference to the adrenal gland as a primary site. It is well known that the direct exposure to arsenicals (especially of vineyard cultivators) may be an important causative factor in the pathogenesis of the disease. A 59-year-old male vineyard cultivator with an epithelioid angiosarcoma of the right adrenal gland is described. The histologic characteristics as well as the immunohistochemical profile of the tumor are presented and the literature is briefly reviewed.
Livaditou
A
A
Air Force and Veterans Administration General Hospital, Athens, Greece.
Alexiou
G
G
Floros
D
D
Filippidis
T
T
Dosios
T
T
Bays
D
D
D000310:Adrenal Gland Neoplasms / Q000139:chemically induced*; D000382:Agricultural Workers' Diseases / Q000139:chemically induced*; D020261:Arsenic Poisoning; D004848:Epithelium / Q000473:pathology; D006394:Hemangiosarcoma / Q000139:chemically induced*; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
D007306:Insecticides