Fungal metabolites. IV. Synthesis of an antibiotic peptide, trichosporin B-V, from Trichoderma polysporum.
The antibiotic icosapeptide trichosporin B-V, which was isolated from Trichoderma polysporum, was synthesized by assembling five peptide fragments via the N,N'-dicyclohexylcarbodiimide method. The synthesized peptide was identical with the natural one.
Iida
A
A
Faculty of Pharmaceutical Sciences, Kyoto University, Japan.
Yoshimatsu
S
S
Sanekata
M
M
Fujita
T
T
D000595:Amino Acid Sequence; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis*; D005656:Fungal Proteins / Q000138:chemical synthesis*; D036341:Intercellular Signaling Peptides and Proteins; D008969:Molecular Sequence Data; D010455:Peptides / Q000138:chemical synthesis; D014242:Trichoderma
D000900:Anti-Bacterial Agents; D005656:Fungal Proteins; D036341:Intercellular Signaling Peptides and Proteins; D010455:Peptides; C056811:trichosporin B-V