Deletion of chromosome 13 in leiomyomas of the uterus.
We report two cases of leiomyomas of the uterus with a deletion of the long arm of chromosome 13. To our knowledge this cytogenetic abnormality as a single change has not been reported previously. One of our cases showed a del(13)(q14q32) and the other a del(13)(q13q33). We discuss the cases and compare our findings with previous ones reported in the literature.
Meloni
A M
AM
Cancer Center, Southwest Biomedical Research Institute and Genetrix, Scottsdale, AZ 85251.
Surti
U
U
Sandberg
A A
AA
D000328:Adult; D002872:Chromosome Deletion; D002882:Chromosomes, Human, Pair 13; D005260:Female; D006801:Humans; D007621:Karyotyping; D007889:Leiomyoma / Q000235:genetics*; D008875:Middle Aged; D014594:Uterine Neoplasms / Q000235:genetics*