title: Venous thromboembolism after brain tumor surgery: a retrospective review.
abstract: We retrospectively reviewed the incidence rate of clinical postoperative deep vein thrombosis and/or pulmonary embolism in 1703 patients undergoing initial craniotomy for meningioma, glioma, or cerebral metastasis. The incidence rate of clinical thromboembolic complications was 1.59% for all tumor groups within the first 4 weeks of surgery. Patients undergoing surgery for meningiomas had a statistically significant increased risk of thromboembolism despite fewer overall perioperative risk factors, when compared with the other tumor groups. The tumor-specific incidence rates of deep vein thrombosis and/or pulmonary embolism for meningioma, glioma, and metastasis were 3.09%, 0.97%, and 1.03%, respectively. Whether this difference was a result of increased surgical time or an inherent property of meningiomas could not be ascertained.
authors.affiliation: Division of Neurosurgery, Toronto Hospital, Ontario, Canada.
authors.forename: A D
authors.initials: AD
authors.lastname: Levi
authors.forename: M C
authors.initials: MC
authors.lastname: Wallace
authors.forename: M
authors.initials: M
authors.lastname: Bernstein
authors.forename: B C
authors.initials: BC
authors.lastname: Walters
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000556:secondary / Q000601:surgery*; D005260:Female; D005910:Glioma / Q000601:surgery; D006801:Humans; D015994:Incidence; D008297:Male; D008577:Meningeal Neoplasms / Q000601:surgery; D008579:Meningioma / Q000601:surgery; D008875:Middle Aged; D011183:Postoperative Complications; D011655:Pulmonary Embolism / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D012189:Retrospective Studies; D012307:Risk Factors; D013923:Thromboembolism / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy