title: Assembly of the cell nucleus.
abstract: Purified DNA can be assembled into structures that closely resemble cell nuclei. The cell-free systems that allow this can be exploited to study assembly pathways for several components of the nucleus. They also offer great opportunities for the experimental analysis of nuclear function.
authors.affiliation: Department of Zoology, University of Cambridge, UK.
authors.forename: R A
authors.initials: RA
authors.lastname: Laskey
authors.forename: G H
authors.initials: GH
authors.lastname: Leno
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000502:physiology* / Q000648:ultrastructure; D002474:Cell-Free System; D002843:Chromatin / Q000502:physiology; D004247:DNA / Q000378:metabolism
chemical_list: D002843:Chromatin; D004247:DNA