Primary amenorrhoea in a triple X female.
The incidence of trisomy X in the newborn population is estimated to be 1 in 1,000 liveborn females. Most of them have normal physical appearance and puberty. Therefore, the reported number of triple X females in the literature is low. We herein report one patient with triple X chromosomes, primary amenorrhoea and normal intelligence. Steroid hormonal levels, clinical and ultrasound findings were suggestive of ovarian failure/gonadal dysgenesis. This case emphasizes the need for chromosomal analysis in women presenting with premature ovarian failure leading to primary or secondary amenorrhoea.
Itu
M
M
Department of Anatomy, All India Institute of Medical Sciences, Ansari Nagar, New Delhi.
Neelam
T
T
Ammini
A C
AC
Kucheria
K
K
D000328:Adult; D000568:Amenorrhea / Q000235:genetics*; D002871:Chromosome Banding; D005260:Female; D006059:Gonadal Dysgenesis / Q000235:genetics*; D006801:Humans; D007360:Intelligence; D012729:Sex Chromosome Aberrations / Q000235:genetics*; D014314:Trisomy; D014960:X Chromosome