title: Idiopathic bladder hyperactivity treated with Ditropan (oxybutynin chloride).
abstract: Ditropan (oxybutynin chloride), a tertiary amine with slight anticholinergic and marked "papaverine-like" direct spasmolytic effects has been administered to 25 patients with idiopathic hyperactive bladder function. The drug reduced voiding frequency and abolished urgency. Control cystometry confirmed a significant increase in bladder capacity. Oral dryness was a tolerable side effect.
authors.affiliation: Department of Urology, Semmelweis University Medical School, Budapest, Hungary.
authors.forename: F
authors.initials: F
authors.lastname: Nagy
authors.forename: A
authors.initials: A
authors.lastname: Hamvas
authors.forename: D
authors.initials: D
authors.lastname: Frang
mesh_terms: D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008333:Mandelic Acids / Q000627:therapeutic use*; D008875:Middle Aged; D010276:Parasympatholytics / Q000627:therapeutic use*; D001750:Urinary Bladder, Neurogenic / Q000188:drug therapy*; D014563:Urodynamics / Q000187:drug effects
chemical_list: D008333:Mandelic Acids; D010276:Parasympatholytics; C005419:oxybutynin