[Arterial hypertension in perimenopausal women; tolerability of etozolin].
Twenty women aged 45-55 years with mild-moderate hypertension were treated for 12 months with etozolin, a new loop diuretic. All patients concluded the study; resting systolic pressure was reduced from 164 +/- 3 to 145 +/- 3 mmHg; diastolic blood pressure dropped from 103 +/- 2 mmHg to 90 +/- 1 mmHg. No changes of blood glucose, blood nitrogen, serum Na+, K+, creatinine, cholesterol, triglycerides were observed, nor serious adverse reaction appeared. In conclusion, etozolin is a safe and effective antihypertensive agent in a selection of hypertensive patients highly sensitive to pharmacological side effects.
Cellina
G
G
Istituti Clinici di Perfezionamento, Cardiologia, Milano.
Binaghi
P
P
De Carolis
M E
ME
Limonta
A
A
Lo Cicero
G
G
Di Michele
R
R
D000959:Antihypertensive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008875:Middle Aged; D013844:Thiazoles / Q000009:adverse effects / Q000627:therapeutic use*
D000959:Antihypertensive Agents; D013844:Thiazoles; C015208:etozolin
Ipertensione arteriosa in donne in età perimenopausale; indagine di tollerabilità dell'etozolina.