Interrelationships between exogenous porcine somatotropin (PST) administration and dietary protein and energy intake on protein deposition capacity and energy metabolism of pigs.
Exogenous porcine somatotropin (PST) administration stimulates protein deposition and inhibits lipogenesis, resulting in dose-related improvements in growth performance and reduction of carcass fat content. However, the associated impacts of this technology on dietary nutrient requirements and energy partitioning between maintenance, protein, and fat remain unclear. Studies with pigs between 25 and 60 kg body weight indicate that, because of unknown improvements in amino acid utilization and(or) in the energy available for protein synthesis, only marginal increases in dietary protein percentage are required to support 20 to 25% improvements in protein deposition induced by PST administration. In contrast, an increased dietary protein concentration is required to support maximal protein deposition in pigs 60 to 100 kg. Exogenous PST administration increased the maintenance energy requirement and altered the relationship between energy intake and protein deposition, although the magnitude of these changes and the consequent effects on expression of dietary protein (amino acid) requirements was influenced by gender. Albeit limited, information suggests that PST alters nutrient demand at the tissue level. Information of this type will form the basis for rational decisions concerning the method for expression of dietary nutrient requirements (% vs g/d) for PST-treated pigs. Further quantitative information is required on the effects of PST dosage on the relationship of protein deposition to energy intake and on any underlying changes in amino acid utilization and metabolism.
Campbell
R G
RG
Animal Research Institute, Werribee Victoria, Australia.
Johnson
R J
RJ
Taverner
M R
MR
King
R H
RH
D000818:Animals; D004044:Dietary Proteins / Q000008:administration & dosage / Q000378:metabolism*; D002149:Energy Intake; D004734:Energy Metabolism / Q000187:drug effects*; D013006:Growth Hormone / Q000494:pharmacology*; D013552:Swine / Q000378:metabolism*
D004044:Dietary Proteins; D013006:Growth Hormone