Domain shuffling during evolution of the proteins of the bacterial phosphotransferase system.
About twenty permeases of the bacterial phosphoenolpyruvate:sugar phosphotransferase system (PTS) have been sequenced and analysed. The results of these analyses suggest that interdomain shuffling, splicing, fusion, deletion, and duplication have occurred repeatedly during their evolution. A uniform nomenclature for these proteins and their domains is proposed.
Saier
M H
MH
Dept. Biology, University of California, San Diego, La Jolla 92093-0116.
Reizer
J
J
D005075:Biological Evolution; D026901:Membrane Transport Proteins / Q000737:chemistry / Q000145:classification* / Q000235:genetics; D010731:Phosphoenolpyruvate Sugar Phosphotransferase System / Q000737:chemistry / Q000145:classification* / Q000235:genetics
D026901:Membrane Transport Proteins; D010731:Phosphoenolpyruvate Sugar Phosphotransferase System