Biological, biochemical and morphological markers of breast disorders and of breast cancer.
The present most useful markers for breast appear to be: a. Actin, myosin and cytokeratins for distinguishing benign (mixed) from malignant (single cell) proliferations. b. Psychological assessment for prediction of long term cancer survival (Pettingale, 1985). c. Helix pomatia lectin binding for distinguishing cancers that have metastasized from those that have not. This is so far limited to 3 independent retrospective studies (Leathem, 1987; Fenlon, 1987; Fukutomi, 1989) and now needs prospective confirmation.
Leathem
A J
AJ
University College and Middlesex School of Medicine, London, U.K.
D015415:Biomarkers / Q000737:chemistry*; D014408:Biomarkers, Tumor / Q000032:analysis*; D001940:Breast / Q000737:chemistry / Q000473:pathology; D001941:Breast Diseases / Q000175:diagnosis* / Q000473:pathology; D001943:Breast Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D011379:Prognosis
D015415:Biomarkers; D014408:Biomarkers, Tumor