A simple method for biliary-enteric anastomosis and chronic bile diversion in the rat.
A simple method of biliary-enteric anastomosis, without the use of surgical microscopy, is described. There were no signs of cholestasis after 3 mo of follow-up. A modified procedure using a silicone elastomer catheter as a stent for the biliary-enteric anastomosis resulted in biliary obstruction within 3 wk after surgery. Our experimental bile duct implantation technique is a simple and useful experimental method for the investigation of chronic biliary diversion and biliary physiology. Additionally, it can be performed safely and easily in a rodent model without sophisticated microscopic techniques.
Rudnicki
M
M
Department of Surgery, University of Cincinnati School of Medicine, Ohio.
McFadden
D W
DW
Fischer
J E
JE
D000714:Anastomosis, Surgical / Q000379:methods*; D000818:Animals; D001652:Bile Ducts / Q000601:surgery*; D001660:Biliary Tract Diseases / Q000503:physiopathology; D002908:Chronic Disease; D004195:Disease Models, Animal; D007422:Intestines / Q000601:surgery*; D008297:Male; D008488:Medical Illustration; D051381:Rats; D011919:Rats, Inbred Strains; D015607:Stents