Inhibitory effects of synthetic histidine-rich peptides on haemagglutination by Bacteroides gingivalis 381.
The haemagglutinating activity of Bacteroides gingivalis 381 was significantly inhibited by the synthetic peptide, Asp-Ser-His-Ala-Lys-Arg-His-His-Gly-Tyr-Lys-Arg-Lys-Phe-His- Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr. However, bradykinin potentiator C, which does not contain cationic amino acids such as L-histidine, L-arginine and L-lysine, had no inhibitory effect.
Murakami
Y
Y
Department of Preventive Dentistry, Osaka University Faculty of Dentistry, Japan.
Takeshita
T
T
Shizukuishi
S
S
Tsunemitsu
A
A
Aimoto
S
S
D000595:Amino Acid Sequence; D001439:Bacteroides / Q000187:drug effects*; D006023:Glycoproteins / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D006384:Hemagglutination / Q000187:drug effects*; D054808:Histatins; D008969:Molecular Sequence Data; D010748:Phosphopeptides / Q000494:pharmacology; D011506:Proteins / Q000008:administration & dosage / Q000138:chemical synthesis / Q000494:pharmacology*; D012471:Salivary Proteins and Peptides / Q000494:pharmacology; D013053:Spectrophotometry; D000099053:Histidine-Rich Glycoprotein
D006023:Glycoproteins; C068075:HTN3 protein, human; D054808:Histatins; D010748:Phosphopeptides; D011506:Proteins; D012471:Salivary Proteins and Peptides; D000099053:Histidine-Rich Glycoprotein; C068074:HTN1 protein, human