[Endocrinology 1989-1990].
In a brief review the author presents selected results of endocrinological research, published in 1989 to 1990. In the sphere of peptide hormones he mentions findings on the reduced level of the endothelial relaxation factor in the blood stream in atherosclerosis, the classification of endothelin with neuropeptides and the existence of a vasopressin antagonist which causes polyuria after operations of the hypothalamus. Hybrid hormones (biotechnologically prepared combined molecules), mammastatins (inhibitors of proliferation of mammary cell cultures lacking in transformed cultures) and adipsin (a peptide factor lacking in some types of experimental obesity) are other recent advances. Findings on endogenous benzodiazepine substances (occupying receptors for diazepines) and of an endogeneous factor for receptors for tetrahydrocanabinols supplement the contemporary picture. Adrenocortex stimulating immunoglobulins may be the cause of hyperplasia of the adrenal cortex, similarly as TSI is the cause of Graves-Basedow's disease. In the latter evidence of a retroviral aetiology was provided.
Schreiber
V
V
Laborator pro endokrinologii a metabolismus pri III. interní klinice 1. lékarské fakulty Univerzity Karlovy, Praha.
D003480:Cushing Syndrome / Q000503:physiopathology; D004704:Endocrinology; D006111:Graves Disease / Q000503:physiopathology; D006728:Hormones / Q000502:physiology; D006801:Humans; D011955:Receptors, Drug
D006728:Hormones; D011955:Receptors, Drug
Endokrinologie 1989-1990.