Diacetyl-splenopentin (BCH 069) did not affect the concentrations of various hormones in men.
We investigated the effect of BCH 069 (similar structure as thymopentin) on concentrations of hormones of the hypophysis, adrenals, gonads and thyroid glands in men after a therapy period of 4 or 6 weeks. No significant effects of BCH 069 three times weekly 50 mg s.c. for 4 weeks or i.v. for 6 weeks on serum concentrations of prolactin, LH, TSH, cortisol, testosterone, progesterone, estradiol and ETR were observed.
Simon
H U
HU
Institute of Clinical Immunology, Friedrich Schiller University Jena/GDR.
Lauterbach
H
H
Börner
A
A
Wachtel
S
S
D000328:Adult; D004958:Estradiol / Q000097:blood; D006728:Hormones / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D009842:Oligopeptides / Q000494:pharmacology*; D010446:Peptide Fragments / Q000494:pharmacology*; D011374:Progesterone / Q000097:blood; D011388:Prolactin / Q000097:blood; D013739:Testosterone / Q000097:blood; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood
C064311:BCH 069; D006728:Hormones; D009842:Oligopeptides; D010446:Peptide Fragments; D013739:Testosterone; D011374:Progesterone; D004958:Estradiol; D011388:Prolactin; D007986:Luteinizing Hormone; D013972:Thyrotropin; D013974:Thyroxine; D006854:Hydrocortisone