[Immunological injury from serum sickness on aortic connective tissue components].
Changes of aortic proteoglycan, collagen and elastic fibers following immunological injury were studied quantitatively and qualitatively under electron microscope after ruthenium red labelling. The results showed that repeated intravenous injections of bovine serum albumin in rabbits activated the synthesis of collagen, elastic fibers and proteoglycan in the aortic wall. The increase of connective tissue components was coincident with the morphological changes of smooth muscle cell.
Zhang
Q G
QG
Department of Cardiology, Jinling Hospital, Nanjing.
Hou
S F
SF
D000418:Albumins; D000818:Animals; D001013:Aorta, Thoracic / Q000378:metabolism* / Q000648:ultrastructure; D003094:Collagen / Q000378:metabolism*; D003238:Connective Tissue / Q000378:metabolism*; D004547:Elastic Tissue / Q000378:metabolism; D009131:Muscle, Smooth, Vascular / Q000378:metabolism; D011509:Proteoglycans / Q000378:metabolism*; D011817:Rabbits; D012713:Serum Sickness / Q000276:immunology / Q000378:metabolism / Q000473:pathology*
D000418:Albumins; D011509:Proteoglycans; D003094:Collagen