[Studies on Stachys sieboldii MIQ. II. Anti-anoxia action and the active constituents].
During screening for the development of drugs from natural products, methanolic extract of tuber of Stachys sieboldii MIQ. (Labiatae) significantly inhibited the lethal induced by KCN in mice. The methanolic extract was fractionated by column chromatography to identify the active constituents. Acteoside and stachysoside C, phenylethanoid glycoside, have a significant effect on the KCN-induced anoxia model.
Yamahara
J
J
Kyoto Pharmaceutical University, Japan.
Kitani
T
T
Kobayashi
H
H
Kawahara
Y
Y
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D000860:Hypoxia / Q000139:chemically induced / Q000188:drug therapy*; D008297:Male; D051379:Mice
D004365:Drugs, Chinese Herbal