Penicillinase production and in vitro susceptibilities of Staphylococcus lugdunensis.
Of 59 clinical isolates of Staphylococcus lugdunensis, 76% were beta-lactamase negative, with penicillin G MICs of less than or equal to 0.13 microgram/ml, and 24% were beta-lactamase positive, with penicillin MICs of greater than or equal to 0.5 microgram/ml. Bimodal distributions were observed also with ampicillin, ampicillin-sulbactam, and amoxicillin-clavulanate. All strains were susceptible to oxacillin, cephalothin, gentamicin, rifampin, and vancomycin; 98% were erythromycin susceptible.
Herchline
T E
TE
Department of Internal Medicine, Ohio State University College of Medicine, Columbus 43210.
Barnishan
J
J
Ayers
L W
LW
Fass
R J
RJ
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests; D010405:Penicillinase / Q000096:biosynthesis*; D013203:Staphylococcal Infections / Q000382:microbiology; D013210:Staphylococcus / Q000187:drug effects / Q000201:enzymology*; D001618:beta-Lactamases / Q000032:analysis / Q000378:metabolism
D000900:Anti-Bacterial Agents; D010405:Penicillinase; D001618:beta-Lactamases