title: [Immunoglobulin E in ankylosing spondylarthritis].
abstract: Ankylosing spondylarthritis (AS) patients (n-95) were examined for IgE concentrations using radioimmunoassay (commercial kits "Pharmacia"). Elevated IgE concentrations (greater than 100 Ku/l) were recorded in 16% out of 45 patients with central AS and in 40% out of 50 patients with peripheral AS (p less than 0.05). High IgE levels showed frequent association with a CIC rise and extraarticular manifestations (uveitis, focal nephritis). It is suggested that AS extraarticular signs arise in response to vascular affection due to IgE overproduction and formation of IgE-containing immune complexes.
authors.forename: N I
authors.initials: NI
authors.lastname: Guseĭnov
authors.forename: E R
authors.initials: ER
authors.lastname: Agababova
authors.forename: E L
authors.initials: EL
authors.lastname: Nasonov
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Lebedin
authors.forename: L E
authors.initials: LE
authors.lastname: Pospelov
authors.forename: A V
authors.initials: AV
authors.lastname: Baenskiĭ
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D008297:Male; D011863:Radioimmunoassay; D013167:Spondylitis, Ankylosing / Q000097:blood / Q000276:immunology*
chemical_list: D007074:Immunoglobulin G
vernacular_title: Immunoglobulin E pri ankiloziruiushchem spondiloartrite.