[Afferent and efferent connections of cortical transplants implanted into the damaged sensorimotor area of the cerebral cortex of mature rats].
Afferent and efferent connections of the transplant, implanted in the previously damaged sensorimotor area of the mature rat cerebral cortex have been studied by means of axonal transport of horseradish peroxidase. For 5 months after transplantation neural axons of the transplant are capable to reach the caudo-putamen and thalamic structures, while connections with the spinal cord are absent. The afferent connections of the transplant are minimal and belong only to the neighbouring areas of the cortex and the caudo-putamen of the recipient brain. Presence of efferent projections to the striate and thalamic structures demonstrates specificity of the projections formed; this can be a morphological base for restoration of the functions lost after the damage of the sensorimotor area of the cortex in mature animals.
Obukhova
G P
GP
Gogeliia
Kh K
KhK
Senatorov
V V
VV
Fiulëp
Z
Z
D000818:Animals; D016380:Brain Tissue Transplantation / Q000379:methods*; D002540:Cerebral Cortex / Q000166:cytology / Q000637:transplantation*; D004624:Embryo Transfer / Q000379:methods*; D006085:Graft Survival / Q000502:physiology; D009044:Motor Cortex / Q000293:injuries / Q000473:pathology / Q000601:surgery*; D009434:Neural Pathways / Q000166:cytology / Q000473:pathology / Q000502:physiology; D009475:Neurons, Afferent / Q000502:physiology / Q000637:transplantation*; D009476:Neurons, Efferent / Q000502:physiology / Q000637:transplantation*; D051381:Rats; D013003:Somatosensory Cortex / Q000293:injuries / Q000473:pathology / Q000601:surgery*
Afferentnye i éfferentnye sviazi korkovykh transplantatov, implantirovannykh v povrezhdennuiu sensomotornuiu oblast' kory bol'shogo mozga vzroslykh krys.