title: In vivo and in vitro evidence for in situ activation and selective covalent binding of acetaminophen (APAP) in mouse kidney.
authors.affiliation: Toxicology Program, Department of Pathobiology, University of Connecticut, Storrs.
authors.forename: S G
authors.initials: SG
authors.lastname: Emeigh Hart
authors.forename: R B
authors.initials: RB
authors.lastname: Birge
authors.forename: R W
authors.initials: RW
authors.lastname: Cartun
authors.forename: C A
authors.initials: CA
authors.lastname: Tyson
authors.forename: J E
authors.initials: JE
authors.lastname: Dabbs
authors.forename: E V
authors.initials: EV
authors.lastname: Nishanian
authors.forename: D S
authors.initials: DS
authors.lastname: Wyand
authors.forename: E A
authors.initials: EA
authors.lastname: Khairallah
authors.forename: S D
authors.initials: SD
authors.lastname: Cohen
mesh_terms: D000082:Acetaminophen / Q000378:metabolism* / Q000493:pharmacokinetics / Q000633:toxicity; D000818:Animals; D001711:Biotransformation; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D007150:Immunohistochemistry; D066298:In Vitro Techniques; D007687:Kidney Tubules, Proximal / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR
chemical_list: D000082:Acetaminophen; D003577:Cytochrome P-450 Enzyme System