[The humoral nature of the colony-stimulating action of bone marrow cells on stromal colony formation in bone marrow cultures].
In 24 hours adherent marrow cell cultures (AMCC) were represented by single stretched fibroblasts. In non-feeder-supplemented AMCC most of the CFU-f remained single fibroblasts or passed through 1-3 cell doublings [correction of dudlings]. The colony stimulating activity of irradiated marrow cells was found to be diffuse across the Millipore filter, which seems to indicate that haemopoietic marrow cells produce a colony stimulating factor which is required for triggering the CFU-f from the Go-period of the cell cycle into cell proliferation.
Fridenshteĭn
A Ia
AIa
Latsinik
N V
NV
Gorskaia
Iu F
IuF
Luriia
E A
EA
D000818:Animals; D000917:Antibody Formation / Q000528:radiation effects; D001853:Bone Marrow / Q000276:immunology* / Q000528:radiation effects; D001854:Bone Marrow Cells; D002448:Cell Adhesion / Q000276:immunology / Q000528:radiation effects; D002455:Cell Division / Q000276:immunology / Q000528:radiation effects; D002478:Cells, Cultured / Q000166:cytology / Q000276:immunology / Q000528:radiation effects; D003114:Colony-Forming Units Assay; D003470:Culture Media; D005347:Fibroblasts / Q000166:cytology / Q000276:immunology / Q000528:radiation effects; D006168:Guinea Pigs; D006412:Hematopoietic Stem Cells / Q000166:cytology / Q000276:immunology* / Q000528:radiation effects; D051379:Mice; D008808:Mice, Inbred CBA; D013997:Time Factors
D003470:Culture Media
Gumoral'naia priroda koloniestimuliruiushchego vozdeĭstviia kostnomozgovykh kletok na obrazovanie stromal'nykh koloniĭ v kul'turakh kostnogo mozga.