Synergism between clindamycin and colloidal bismuth subcitrate against Helicobacter (Campylobacter) pylori in vitro.
A combination of clindamycin and colloidal bismuth subcitrate was evaluated for synergistic inhibition of Helicobacter pylori employing the agar dilution method. A total of 47 clinical isolates of Helicobacter pylori were examined. Synergistic interaction was observed in 36%, additive behaviour in 64% of the strains. No antagonism could be detected.
Vogt
K
K
Institut für Medizinische Mikrobiologie und Infektionsimmunologie der Freien Universität, Berlin.
Hahn
H
H
D000897:Anti-Ulcer Agents / Q000494:pharmacology*; D002981:Clindamycin / Q000494:pharmacology*; D004357:Drug Synergism; D016480:Helicobacter pylori / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests; D009942:Organometallic Compounds / Q000494:pharmacology*
D000897:Anti-Ulcer Agents; D009942:Organometallic Compounds; D002981:Clindamycin; C002791:bismuth tripotassium dicitrate