Monoamine oxidase activity in blood platelets of migraine patients.
Biochemical changes in platelets of migraine patients during the attacks have been reported before, however there are some conflicting results. In an attempt to define the biochemical lesion in the platelets, we have carried out a survey of platelets monoamine oxidase in migraine patients with and without aura. Platelet MAO activity in platelets from migraine patients was significantly reduced when compared with normal platelets.
Caramona
M M
MM
Laboratório de Farmacologia, Faculdade de Farmácia, Coimbra, Portugal.
Cotrim
M D
MD
Ribeiro
C F
CF
Macedo
T
T
D000328:Adult; D001792:Blood Platelets / Q000201:enzymology*; D001798:Blood Proteins / Q000378:metabolism; D004032:Diet; D005260:Female; D006801:Humans; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000097:blood / Q000201:enzymology*; D008995:Monoamine Oxidase / Q000097:blood*
D001798:Blood Proteins; D008995:Monoamine Oxidase