title: [The relationship of endocrine ophthalmopathy to the thyroid status and to the indices of an autoimmune lesion of the thyroid].
abstract: The paper is devoted to a study of the pathogenetic relationship of endocrine ophthalmopathy with thyroid diseases. Altogether 76 patients with endocrine ophthalmopathy combined with various thyroid lesions (diffuse toxic goiter, Hashimoto's disease, primary hypothyrosis) and without thyroid diseases were investigated. The serum level of thyroid hormones, the content of Ig A, M, G, thyroglobulin and the presence of antithyroid antibodies were analyzed. HLA typing by A, B, C, D2 loci was done for a group of patients. The results did not show correlation of the origin and gravity of ophthalmopathy either with thyroid function or with the factors determining thyroid affection. Some differences in the genetic markers of endocrine ophthalmopathy and autoimmune thyroid diseases were also established.
authors.forename: M P
authors.initials: MP
authors.lastname: Biriukova
authors.forename: V I
authors.initials: VI
authors.lastname: Kandror
authors.forename: I V
authors.initials: IV
authors.lastname: Kriukova
authors.forename: E V
authors.initials: EV
authors.lastname: Konnova
authors.forename: G I
authors.initials: GI
authors.lastname: Kozlov
authors.forename: S S
authors.initials: SS
authors.lastname: Efuni
authors.forename: I S
authors.initials: IS
authors.lastname: Polianskaia
mesh_terms: D000328:Adult; D000368:Aged; D000906:Antibodies / Q000097:blood; D001327:Autoimmune Diseases / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D005128:Eye Diseases / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006680:HLA Antigens / Q000097:blood; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008297:Male; D008875:Middle Aged; D013954:Thyroglobulin / Q000097:blood / Q000276:immunology; D013959:Thyroid Diseases / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D013961:Thyroid Gland / Q000503:physiopathology*; D013963:Thyroid Hormones / Q000097:blood; D013972:Thyrotropin / Q000097:blood
chemical_list: D000906:Antibodies; D006680:HLA Antigens; D007136:Immunoglobulins; D013963:Thyroid Hormones; D013972:Thyrotropin; D013954:Thyroglobulin
vernacular_title: Sviaz' éndokrinnoĭ oftal'mopatii s tireoidnym statusom i pokazateliami autoimmunnogo porazheniia shchitovidnoĭ zhelezy.