Stereotactic implantation of fetal mesencephalon.
Twelve patients with advanced Parkinson's disease have been improved by transplantation of fetal mesencephalon into the caudate nucleus. No immunosuppression had been used. The human allogeneic transplantation window is wide.
Hitchcock
E R
ER
Department of Neurosurgery, Midland Centre for Neurosurgery and Neurology, Warley, West Midlands, UK.
Kenny
B G
BG
Clough
C G
CG
Hughes
R C
RC
Henderson
B T
BT
Detta
A
A
D000328:Adult; D016380:Brain Tissue Transplantation / Q000379:methods*; D002421:Caudate Nucleus / Q000601:surgery*; D005260:Female; D016332:Fetal Tissue Transplantation / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008636:Mesencephalon / Q000196:embryology / Q000637:transplantation*; D008875:Middle Aged; D010300:Parkinson Disease / Q000175:diagnosis / Q000601:surgery*; D011183:Postoperative Complications / Q000175:diagnosis; D013238:Stereotaxic Techniques