Morphological observations on rat livers perfused with a perfluorodecalin + N,N-perfluorodiethylcyclohexylamine emulsion having oxyphoretic properties.
Perfusion of Rat liver with an oxyphoretic emulsion containing a mixture of perfluorodecalin and N,N-perfluorodiethylcyclohexylamine provides a good oxygenation of the tissue. During perfusion hepatocytes take up some emulsion micelles and this uptake markedly increases when tissue perfusion is suboptimal.
Branca
D
D
Department of Biological Chemistry, University of Padova.
Chiarelli
S M
SM
Vincenti
E
E
Bianco
R
R
Giron
F
F
Scutari
G
G
D000818:Animals; D001802:Blood Substitutes / Q000493:pharmacokinetics*; D005466:Fluorocarbons / Q000493:pharmacokinetics*; D008099:Liver / Q000378:metabolism / Q000473:pathology*; D010477:Perfusion; D051381:Rats; D011919:Rats, Inbred Strains
D001802:Blood Substitutes; D005466:Fluorocarbons; C060999:N,N-perfluorodiethylcyclohexylamine; C008805:perfluorodecalin