title: [Assessment of left ventricular diastolic function of the hypertensive heart using Doppler echocardiography method before and after intravenous administration of verapamil].
abstract: Left ventricular diastolic function was studied by Doppler echocardiography in 18 patients with early signs of hypertensive heart before and after intravenous verapamil, 0.15 mg/kg. Eleven patients without cardiovascular disease comprised a control group. A significant deterioration of left ventricular diastolic function parameters was revealed in patients with hypertensive heart. There was a normalization of left ventricular blood filling following 30 min of verapamil use, which was associated with the direct action of the drug on the myocardium and with its vasodilating effect.
authors.forename: M A
authors.initials: MA
authors.lastname: Osipov
authors.forename: S E
authors.initials: SE
authors.lastname: Bashchinskiĭ
authors.forename: B Ia
authors.initials: BIa
authors.lastname: Bart
mesh_terms: D000328:Adult; D000368:Aged; D003971:Diastole; D015150:Echocardiography, Doppler; D005260:Female; D006352:Heart Ventricles / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D014700:Verapamil / Q000008:administration & dosage*
chemical_list: D014700:Verapamil
vernacular_title: Otsenka diastolicheskoĭ funktsii levogo zhedulochka pri gipertonicheskom serdtse metodom doppler-ékhokardiografii do i posle vnutrivennogo vvdeniia verapamila.