Sensory neuropeptides are involved in cigarette smoke induced airway hyperreactivity in guinea-pig.
Acute cigarette smoke exposure in anaesthetized guinea-pigs resulted in non-specific airway hyperreactivity associated with inflammatory cell influx within the lung. Sensory neuropeptides seem to be involved in the genesis of smoke induced airway hyperreactivity.
Daffonchio
L
L
Institute of Pharmacological Sciences, University of Milan, Italy.
Hernandez
A
A
Omini
C
C
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D016084:Bronchoconstriction; D002211:Capsaicin / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D006168:Guinea Pigs; D006632:Histamine / Q000494:pharmacology; D006854:Hydrocortisone / Q000494:pharmacology; D008297:Male; D009479:Neuropeptides / Q000502:physiology*; D010947:Plants, Toxic; D012130:Respiratory Hypersensitivity / Q000209:etiology*; D012677:Sensation / Q000502:physiology*; D012906:Smoke / Q000009:adverse effects*; D014026:Nicotiana; D014628:Vagotomy
D009479:Neuropeptides; D012906:Smoke; D006632:Histamine; D000109:Acetylcholine; D002211:Capsaicin; D006854:Hydrocortisone