title: Effect of Cd2+ on ATP synthesis coupled to electron transfer in cadmium-resistant and -sensitive Staphylococcus aureus.
abstract: In the Cd2(+)-resistant Staphylococcus aureus 17810R which contains the plasmid-coded Cd2+ efflux system, accumulation of Cd2+ was highly reduced. Consequently, neither respiration nor ATP synthesis coupled to electron transfer were inhibited. The plasmidless S. aureus strain 17810S accumulated Cd2+ via the Mn2+ porter down the membrane potential (delta phi) which resulted in inhibition of respiration and of ATP synthesis.
authors.affiliation: Department of Pharmaceutical Microbiology, Medical Academy, Lublin, Poland.
authors.forename: Z
authors.initials: Z
authors.lastname: Tynecka
authors.forename: A
authors.initials: A
authors.lastname: Malm
authors.forename: J
authors.initials: J
authors.lastname: Zajac
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism*; D002104:Cadmium / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D004579:Electron Transport; D007476:Ionophores / Q000494:pharmacology; D011815:R Factors; D013211:Staphylococcus aureus / Q000187:drug effects / Q000235:genetics / Q000378:metabolism*
chemical_list: D007476:Ionophores; D002104:Cadmium; D000255:Adenosine Triphosphate