Small GTP-binding proteins in vesicular transport.
Recent recognition of the abundance of small GTP-binding proteins in eukaryotic cells has sparked off a search for the possible function of these proteins. Evidence is accumulating that SAR1, ARF, SEC4 and YPT1 in yeast and the rab and arf family in mammalian cells play a central role in the regulation of vesicle transport and organelle function.
Balch
W E
WE
Department of Molecular Biology, Research Institute of Scripps Clinic, La Jolla, CA 92037.
D000818:Animals; D001692:Biological Transport; D002118:Calcium / Q000378:metabolism; D004721:Endoplasmic Reticulum / Q000378:metabolism*; D020690:GTPase-Activating Proteins; D006056:Golgi Apparatus / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism*
D020690:GTPase-Activating Proteins; D011506:Proteins; D002118:Calcium