title: Restriction site mapping of adenovirus type 8 genome types.
abstract: The DNA of 60 adenovirus type 8 (AV8) isolates (collected during the period 1961 to 1982, mostly in Western Germany) was analysed by 6 endonucleases and revealed 6 different genome types, thus implying that the variability of AV8 is relatively low. It was found that 45 isolates belonged to the genome type D1. Restriction site maps of a prototype D1 and of all deviating restriction variants were elaborated for enzymes BamHI, BglII, Hind-III and SalI.
authors.affiliation: Nationales Referenzzentrum für Adenoviren, Institut für Virologie und Seuchenhygiene, Medizinische Hochschule, Hannover, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Adrian
authors.forename: U
authors.initials: U
authors.lastname: Wolf
authors.forename: H J
authors.initials: HJ
authors.lastname: Lauer
authors.forename: R
authors.initials: R
authors.lastname: Wigand
mesh_terms: D000256:Adenoviridae / Q000235:genetics*; D002478:Cells, Cultured; D004279:DNA, Viral / Q000032:analysis*; D014644:Genetic Variation; D006801:Humans; D015183:Restriction Mapping
chemical_list: D004279:DNA, Viral