title: Results of psychological testing of patients aged 3-6 years.
abstract: Cognitive development of early treated PKU children (132) was investigated by intelligence tests, tests for visual perception, motor and language development. Deviations from test norms occurred at 5 years of age concerning performance IQ, mathematical thinking, and visual perception. With the exception of mathematical thinking, "normal" results were obtained at the age of 6 years. Correlation with levels of plasma Phe revealed a relation between quality of dietary control and performance IQ. Results are discussed in light of methodological aspects and with respect to treatment consequence.
authors.affiliation: Ruprecht-Karls-Universität Heidelberg, Kinderklinik, Federal Republic of Germany.
authors.forename: U
authors.initials: U
authors.lastname: Michel
authors.forename: E
authors.initials: E
authors.lastname: Schmidt
authors.forename: U
authors.initials: U
authors.lastname: Batzler
mesh_terms: D002675:Child, Preschool; D003071:Cognition / Q000502:physiology; D003430:Cross-Sectional Studies; D006801:Humans; D007361:Intelligence Tests; D007804:Language Development; D008137:Longitudinal Studies; D010649:Phenylalanine / Q000097:blood; D010661:Phenylketonurias / Q000097:blood / Q000178:diet therapy / Q000523:psychology*; D011581:Psychological Tests
chemical_list: D010649:Phenylalanine