[The detection of tubazid and saliuzid metabolites in internal organs and biological fluids].
Detection of tubaside and saluside metabolites by methanol extraction from homogenized object with subsequent investigation by UV spectrophotometry, microcrystalloscopy, thin-layer chromatography and coloured reaction methods is suggested. Sensitivity for hydrazine, acetylisoniazid was 0.1 mg%, for opianic and isonicotinic acids--0.05 mg%.
Fartushnyĭ
A F
AF
Matveenko
V I
VI
Bakshinskaia
R E
RE
Matveenko
N I
NI
D000995:Antitubercular Agents / Q000032:analysis* / Q000493:pharmacokinetics; D001826:Body Fluids / Q000737:chemistry*; D002102:Cadaver; D002855:Chromatography, Thin Layer / Q000379:methods; D003124:Colorimetry / Q000379:methods; D003461:Crystallography / Q000379:methods; D006801:Humans; D007538:Isoniazid / Q000031:analogs & derivatives / Q000737:chemistry*; D007668:Kidney / Q000737:chemistry*; D008099:Liver / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet / Q000379:methods
D000995:Antitubercular Agents; C009200:saluzid; D007538:Isoniazid
Obnaruzhenie metabolitov tubazida i saliuzida vo vnutrennikh organakh i biologicheskikh zhidkostiakh.