title: The human kininogen gene (KNG) mapped to chromosome 3q26-qter by analysis of somatic cell hybrids using the polymerase chain reaction.
abstract: Kinins, peptide products of kininogens, may be involved in hypertensive and diabetic diseases, and inflammatory disorders. The human kininogen gene (KNG) has been mapped to chromosome 3, using a panel of human-hamster somatic cell hybrids by polymerase chain reaction of hybrid DNA with gene-specific primers. KNG was further assigned to 3q26-3qter, using DNA from a second panel of chromosome 3 deletion mapping cell hybrids.
authors.affiliation: Department of Biological Sciences, Rutgers, State University of New Jersey, Piscataway 08855-1059.
authors.forename: D
authors.initials: D
authors.lastname: Fong
authors.forename: D I
authors.initials: DI
authors.lastname: Smith
authors.forename: W T
authors.initials: WT
authors.lastname: Hsieh
mesh_terms: D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D002893:Chromosomes, Human, Pair 3; D006224:Cricetinae; D004587:Electrophoresis, Agar Gel; D006801:Humans; D006822:Hybrid Cells; D066298:In Vitro Techniques; D007704:Kininogens / Q000235:genetics*; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction
chemical_list: D007704:Kininogens