title: Clonazepam in neonatal seizures: dose regimens and therapeutic efficacy.
abstract: The attempt has been made to define the optimal dose regimen of clonazepam in newborns suffering from neonatal convulsions. Results obtained from 22 patients (GA 28-41 weeks; PNA 4 h to 23 days) indicated that a dose of 0.1 mg/kg every 24 h was satisfactory in the majority of the patients. It is recommended as a starting regimen.
authors.affiliation: Service de Médecine Néonatale, Maternité Régionale A. Pinard, Nancy, France.
authors.forename: M
authors.initials: M
authors.lastname: André
authors.forename: M J
authors.initials: MJ
authors.lastname: Boutroy
authors.forename: G
authors.initials: G
authors.lastname: Bianchetti
authors.forename: P
authors.initials: P
authors.lastname: Vert
authors.forename: P L
authors.initials: PL
authors.lastname: Morselli
mesh_terms: D001238:Asphyxia Neonatorum / Q000150:complications; D002543:Cerebral Hemorrhage / Q000150:complications; D002998:Clonazepam / Q000097:blood / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000097:blood / Q000188:drug therapy; D007239:Infections / Q000150:complications; D008297:Male; D012640:Seizures / Q000188:drug therapy* / Q000209:etiology
chemical_list: D002998:Clonazepam