title: [Chronic hepatitis delta--the course and approaches to therapy].
abstract: Variants of chronic hepatitis delta (CHD) course were studied in 94 patients. Slow progress (for decades) occurred most frequently, while rapid progress to hepatic cirrhosis (for 1-2 years) or benign course presenting as greater than 3-year remission were rare findings. In addition to routine therapeutic modalities, except corticosteroids, 43 CHD patients received recombinant alpha 2-interferon (reaferon). Follow-up results evaluated separately for hepatic cirrhosis and free of it CHD patients support clinical promise of Soviet recombinant alpha 2-interferon against CHD.
authors.forename: N P
authors.initials: NP
authors.lastname: Blokhina
authors.forename: E S
authors.initials: ES
authors.lastname: Ketiladze
authors.forename: E I
authors.initials: EI
authors.lastname: Kelli
authors.forename: S O
authors.initials: SO
authors.lastname: Viazov
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D005260:Female; D003699:Hepatitis D / Q000175:diagnosis* / Q000628:therapy; D006521:Hepatitis, Chronic / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D007370:Interferon Type I / Q000009:adverse effects / Q000627:therapeutic use*; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D008297:Male; D008875:Middle Aged; D011994:Recombinant Proteins; D012737:Sex Factors; D013997:Time Factors
chemical_list: D007370:Interferon Type I; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins
vernacular_title: Techenie khronicheskogo gepatita del'ta i podkhody k lecheniiu.