Evolution of ischemic heart disease risk factors in "The Bucharest Multifactorial Preventive Trial of Coronary Heart Disease" after 15-year follow-up.
The paper presents the evolution of the levels of smoking, hypercholesterolemia, essential hypertension and obesity in the course of a prophylactic action carried out for 15 years (1971-1986) in a group of 5000 males aged 40-60 years. In the group still available after 15 years of follow up consisting of 2000 subjects, a decrease was obtained in the number of smokers, from 22.3% to 5.6% of hypercholesterolemia from 31.3% to 23.7%. The cumulated incidence of essential hypertension has increased from 15.5% to 36.7% and of obesity from 12.6% to 14.4%. At the same time the incidence of angina pectoris and myocardial infarction increased from 1.1% to 5.3%. For comparison are presented data obtained in a similar control group.
Damşa
T
T
N. Gh. Lupu Institute of Internal Medicine, Bucharest, Romania.
Schioiu-Costache
L
L
Georgescu
M
M
Popescu
A
A
Theodorini
S
S
Teodorescu
S
S
Stãnescu
C
C
Mitu
S
S
D000328:Adult; D003327:Coronary Disease / Q000453:epidemiology* / Q000517:prevention & control; D005500:Follow-Up Studies; D006801:Humans; D006937:Hypercholesterolemia / Q000453:epidemiology; D006973:Hypertension / Q000453:epidemiology; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012383:Romania / Q000453:epidemiology; D012907:Smoking / Q000453:epidemiology; D014505:Urban Population / Q000706:statistics & numerical data