title: [The hemolytic-uremic syndrome during contraceptive prevention with Rigevidon].
abstract: A case of a 20-year-old woman who developed a hemolytic-uremic syndrome while using the contraceptive drug Rigevidon is reported. Clinically the disease was manifested by acute renal failure, thrombocytopenic purpura and hemolytic anemia. The treatment with antiaggregants, anticoagulants, hemodialysis and plasmapheresis was without effect. The diagnosis was proved by the postmortem examination. The risks of the use of oral contraceptives and the need of new and better methods for contraception are discussed.
authors.forename: D
authors.initials: D
authors.lastname: Dimitrakov
authors.forename: T
authors.initials: T
authors.lastname: Despotov
authors.forename: Z
authors.initials: Z
authors.lastname: Tsvetkova
authors.forename: E
authors.initials: E
authors.lastname: Kumchev
authors.forename: E
authors.initials: E
authors.lastname: Kapon
authors.forename: S
authors.initials: S
authors.lastname: Pandeva
authors.forename: M
authors.initials: M
authors.lastname: Kuzmova
authors.forename: P
authors.initials: P
authors.lastname: Stavrev
authors.forename: A
authors.initials: A
authors.lastname: Sotirov
authors.forename: Zh
authors.initials: Zh
authors.lastname: Peshev
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology; D000328:Adult; D003278:Contraceptives, Oral, Hormonal / Q000009:adverse effects*; D004997:Ethinyl Estradiol / Q000009:adverse effects*; D019304:Ethinyl Estradiol-Norgestrel Combination; D005260:Female; D006463:Hemolytic-Uremic Syndrome / Q000139:chemically induced* / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D009644:Norgestrel / Q000009:adverse effects*; D011696:Purpura, Thrombocytopenic / Q000139:chemically induced / Q000175:diagnosis / Q000473:pathology; D013997:Time Factors
chemical_list: D003278:Contraceptives, Oral, Hormonal; D009644:Norgestrel; D004997:Ethinyl Estradiol; D019304:Ethinyl Estradiol-Norgestrel Combination
vernacular_title: Khemolitichno-uremichen sindrom po vreme na kontratseptivna profilaktika s Rigevidon.