title: Prolonged T1 in patients with liver cirrhosis: an in vivo MRI study.
abstract: Fifteen patients with liver cirrhosis and two control groups were examined. The first control group consisted of 7 healthy volunteers, and the second group of 17 patients with nonfocal liver diseases. The T1 and T2 relaxation times were calculated from signal intensities read out from a region of interest centrally located in the liver. T1 relaxation time was longer in the patients with liver cirrhosis than in the two reference groups. Ten patients had a liver biopsy taken prior to the MRI study. No correlation was found between histopathology and the measured relaxation times.
authors.affiliation: Department of Magnetic Resonance, Hvidovre Hospital, University of Copenhagen, Denmark.
authors.forename: C
authors.initials: C
authors.lastname: Thomsen
authors.forename: P
authors.initials: P
authors.lastname: Christoffersen
authors.forename: O
authors.initials: O
authors.lastname: Henriksen
authors.forename: E
authors.initials: E
authors.lastname: Juhl
mesh_terms: D006801:Humans; D008099:Liver / Q000033:anatomy & histology*; D008103:Liver Cirrhosis / Q000175:diagnosis* / Q000473:pathology; D008107:Liver Diseases / Q000175:diagnosis* / Q000473:pathology; D008232:Lymphoproliferative Disorders / Q000175:diagnosis / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods; D009196:Myeloproliferative Disorders / Q000175:diagnosis / Q000473:pathology; D013163:Splenomegaly / Q000175:diagnosis / Q000473:pathology; D013997:Time Factors