[A histochemical analysis of the oxidative-reductive enzymes in the cardiomyocytes of mature and old rats following low-dose external gamma irradiation].
The effect of gamma rays in low dose (0.5 Gy) on enzymes activity of glycolysis, tricarboxylic acid cycle, diaphorases in cardiomyocytes of adult and old albino rats at 3-, 10- and 30-day after irradiation was studied. It was established that the diaphorases activity decreased, the lactate dehydrogenase activity increased whereas that of other tricarboxylic acid cycle enzymes underwent phase changes. In result discoordination of redox enzymes in cardiomyocytes of rats hypoxic state develops. The question of the age sensitivity of heart to irradiation in low dose is discussed.
Ambros'ev
A P
AP
Vereshchako
G G
GG
Banetskaia
N V
NV
D000375:Aging / Q000378:metabolism / Q000528:radiation effects*; D000818:Animals; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D006321:Heart / Q000528:radiation effects*; D006651:Histocytochemistry; D008297:Male; D009206:Myocardium / Q000201:enzymology*; D010084:Oxidation-Reduction / Q000528:radiation effects; D010088:Oxidoreductases / Q000378:metabolism / Q000528:radiation effects*; D051381:Rats; D011919:Rats, Inbred Strains; D013997:Time Factors
D010088:Oxidoreductases
Gistokhimicheskiĭ analiz okislitel'no-vosstanovitel'nykh fermentov v kardiomiotsitakh zrelykh i starykh krys posle vneshnego gamma-oblucheniia v maloĭ doze.