[The effect of opioid neuropeptides on the cholino- and adrenoreactivity of the sensorimotor cortex cells in rats].
The effect of two neuropeptides, dalargine and betaendorphine, on cholino- and adrenoreactivity of sensorimotor cortex cells has been studied in immobilized rats in acute experiments. Subcutaneous administration of the peptides led to redistribution of cells according to the type of their reaction and to changes in intensity of neuronal reactions to the applied neurotransmitters. The observed changes in chemoreactive properties of cortical neurons under the influence of the neuropeptides may play a certain part in the processes of learning and memory.
Koshtoiants
O Kh
OKh
Antipina
M Iu
MIu
Kulikov
M A
MA
D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D004347:Drug Interactions; D004723:Endorphins / Q000494:pharmacology*; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives / Q000494:pharmacology; D009044:Motor Cortex / Q000187:drug effects* / Q000502:physiology; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D009638:Norepinephrine / Q000494:pharmacology; D051381:Rats; D011941:Receptors, Adrenergic / Q000187:drug effects* / Q000502:physiology; D011950:Receptors, Cholinergic / Q000187:drug effects* / Q000502:physiology; D001615:beta-Endorphin / Q000494:pharmacology
D004723:Endorphins; D011941:Receptors, Adrenergic; D011950:Receptors, Cholinergic; D001615:beta-Endorphin; D016308:Enkephalin, Leucine-2-Alanine; D000109:Acetylcholine; C040996:enkephalin-Leu, Ala(2)-Arg(6)-; D009638:Norepinephrine
Vliianie opioidnykh neĭropeptidov na kholino- i adrenoreaktivnost' kletok sensomotornoĭ kory krys.