title: DMSO induces the formation of microfilament bundles in nuclei of zoospores of Phytophthora infestans (Mont.) De Bary (Oomycetes, Pythiaceae).
abstract: Cytoskeletons of zoospores of the fungus Phytophthora infestans (Mont.) De Bary treated with dimethylsulfoxide (DMSO) were studied by electron microscopy. High concentrations of DMSO (greater than or equal to 5%) resulted in lysis of the cells and disturbances of the microtubule pattern of flagellar axonemes. Treatment with low concentrations of DMSO (1%-0.1%) induced the formation of bundled intranuclear filaments. It is assumed that these filament bundles should consist of F-actin.
authors.affiliation: Central Institute of Microbiology and Experimental Therapy, Academy of Sciences of the GDR, Jena.
authors.forename: E
authors.initials: E
authors.lastname: Jelke
authors.forename: B
authors.initials: B
authors.lastname: Oertel
mesh_terms: D008841:Actin Cytoskeleton / Q000187:drug effects / Q000648:ultrastructure*; D002467:Cell Nucleus / Q000187:drug effects / Q000648:ultrastructure*; D004121:Dimethyl Sulfoxide / Q000494:pharmacology*; D008854:Microscopy, Electron; D010838:Phytophthora / Q000187:drug effects / Q000502:physiology / Q000648:ultrastructure*; D013172:Spores, Fungal / Q000187:drug effects / Q000648:ultrastructure
chemical_list: D004121:Dimethyl Sulfoxide