title: [Neonatal systemic candidiasis].
abstract: We analysed 7 cases of systemic candida sp. infection diagnosed between 1986 to 1989. Clinical presentation was of sepsis. Evolution was favorable in all, excepting two cases that died due to a candidiasic meningitis and a candidiasic aortic thrombosis, respectively. Almost all patients were treated with amphotericin B only. A newborn had signs of toxicity (thrombocytopenia). We emphasize the importance of a prompt diagnosis and treatment and the effectivity of amphotericin B for systemic candidiasis, besides of its rare toxicity in newborns.
authors.affiliation: Departamento de Pediatría, Hospital 12 de Octubre, Madrid.
authors.forename: B
authors.initials: B
authors.lastname: Flores Antón
authors.forename: M C
authors.initials: MC
authors.lastname: Barrio Andrés
authors.forename: C
authors.initials: C
authors.lastname: de Alba Romero
authors.forename: V
authors.initials: V
authors.lastname: Orbe León
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002177:Candidiasis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D005437:Flucytosine / Q000627:therapeutic use; D006801:Humans; D007231:Infant, Newborn; D008297:Male
chemical_list: D000900:Anti-Bacterial Agents; D000666:Amphotericin B; D005437:Flucytosine
vernacular_title: Candidiasis sistémica neonatal.