title: [Azidothymidine and the nervous system].
abstract: By December 1988 reports on 525 ARC- (AIDS-Related Complex) and AIDS-patients with neurological or neuropsychological signs treated with Zidovudine (AZT = 3'-Azido-2,3'Dideoxythymidine) had been published in literature. In 204 (38.8%) cases of HIV infection a temporary improvement in the neurological deficits was reported. Peripheral and central neurological side-effects were observed in 124 (23.6%) patients.
authors.affiliation: Univ.-Nerven-Klinik München.
authors.forename: R R
authors.initials: RR
authors.lastname: Riedel
authors.forename: L
authors.initials: L
authors.lastname: Bader
authors.forename: L
authors.initials: L
authors.lastname: Gürtler
authors.forename: J
authors.initials: J
authors.lastname: Eberle
authors.forename: W
authors.initials: W
authors.lastname: Günther
authors.forename: D
authors.initials: D
authors.lastname: Naber
mesh_terms: D015526:AIDS Dementia Complex / Q000188:drug therapy*; D002459:Cell Fusion / Q000187:drug effects; D002493:Central Nervous System Diseases / Q000139:chemically induced; D009474:Neurons / Q000187:drug effects; D013937:Thymidine Kinase / Q000037:antagonists & inhibitors; D015215:Zidovudine / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D015215:Zidovudine; D013937:Thymidine Kinase
vernacular_title: Azidothymidin und das Nervensystem.