Stereotactic transplantation of adrenal medullary tissue in Parkinson's disease.
Autograft of adrenal medullary tissue into the striatum was performed stereotactically in 5 patients with severe Parkinson's disease. Two patients had suffered from side effects of L-dopa, and 3 were severely disabled without L-dopa preoperatively. After surgery, the dosage of L-dopa could be reduced in 1, and L-dopa could be withdrawn in 4 patients. The results of adrenal medullary tissue transplantation in Parkinson's disease are analyzed.
Chung
S S
SS
Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea.
Kim
S H
SH
Yoon
D H
DH
D000203:Activities of Daily Living; D000313:Adrenal Medulla / Q000637:transplantation*; D002421:Caudate Nucleus / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D009460:Neurologic Examination; D010300:Parkinson Disease / Q000175:diagnosis / Q000601:surgery*; D011183:Postoperative Complications / Q000175:diagnosis; D011699:Putamen / Q000601:surgery*; D013238:Stereotaxic Techniques