[Activity of lysosomal enzymes in cardiomyocytes, hepatocytes and blood in experimental diphtheritic intoxication].
Non-sedimentable activity of N-acetyl-beta-D-galactosaminidase and beta-D-glucuronidase was studied in left and right ventricles of myocardium, in liver tissue and blood plasma of rabbits with experimental diphtheritic intoxication. Specific dynamics of the enzymatic activity was found during the diphtheritic intoxication, indicating that various mechanisms were involved in regulation of lysosomal membranes permeability under conditions of the disease.
Frolov
V A
VA
Shkirmante
B K
BK
D000818:Animals; D004167:Diphtheria Toxin; D005966:Glucuronidase / Q000097:blood / Q000378:metabolism; D006321:Heart / Q000187:drug effects*; D006596:Hexosaminidases / Q000097:blood / Q000378:metabolism; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008247:Lysosomes / Q000187:drug effects* / Q000201:enzymology; D008297:Male; D009206:Myocardium / Q000201:enzymology*; D011817:Rabbits
D004167:Diphtheria Toxin; D006596:Hexosaminidases; D005966:Glucuronidase
Aktivnost' lizosomnykh fermentov v kardiomiotsitakh, gepatotsitakh i krovi v dinamike éksperimental'noĭ difteriĭnoĭ intoksikatsii.