The interaction of Rh(II) and Rh(III) with DNA.
The interaction of Rh2(II)(acetate)4, cis-[Rh(III)(en)2Cl2] Cl (en = ethylenediamine) and [Rh(III) (NH3)5Cl]Cl2 with calf thymus DNA has been studied at various r values [formula; see text] and interaction times. Electronic spectra, melting and cooling curves and sedimentation data indicate no interaction of the acetate complex with DNA, except in the case of a high r value and long interaction time. The other two complexes have been found to interact with the phosphate groups, thus stabilizing the macromolecule.
Tselepi-Kalouli
E
E
Institute of Physical Chemistry, National Research Center, Democritos, Athens, Greece.
Katsaros
N
N
D000818:Animals; D002417:Cattle; D002499:Centrifugation, Density Gradient; D004247:DNA / Q000378:metabolism*; D006358:Hot Temperature; D012238:Rhodium / Q000378:metabolism*; D013053:Spectrophotometry
D004247:DNA; D012238:Rhodium