Sporadic cerebral amyloid angiopathy with giant cell reaction.
We report a case of intracerebral hemorrhages due to sporadic cerebral amyloid angiopathy in a 43-year-old male with a luxuriant giant cell reaction. The amyloid was resistant to potassium permanganate-sulfuric acid oxidation and reacted with an antiserum to synthetic beta-protein. The distribution and histologic characteristics of the multinucleated giant cell reaction suggest that it represents a foreign-body reaction rather than giant cell arteritis.
Powers
J M
JM
Division of Neuropathology, Columbia University, College of Physicians and Surgeons, New York, NY 10032.
Stein
B M
BM
Torres
R A
RA
D000328:Adult; D000682:Amyloid / Q000032:analysis*; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology*; D002543:Cerebral Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed
D000682:Amyloid