[Effect of the oral administration of zinc on metastasis after intravenous application of benzpyrene-induced rat sarcoma cells].
In experimental investigations it was shown that rats having received drinking water enriched by zinc acetate (22.8 mmol/l) developed significantly more pulmonary metastases after an intravenous infection of cells of a benzpyrene-induced rat sarcoma than rats receiving normal drinking water. This increase is caused by an increase of the number of rats developed metastases as well as the number of metastases of the individual rat.
Rath
F W
FW
Institut für Pathologische Anatomie, Martin-Luther-Universität Halle-Wittenberg.
Körtge
R
R
Haase
P
P
Bismarck
M
M
D000085:Acetates / Q000008:administration & dosage / Q000494:pharmacology*; D019342:Acetic Acid; D000284:Administration, Oral; D000818:Animals; D001580:Benzopyrenes; D008175:Lung Neoplasms / Q000378:metabolism* / Q000473:pathology; D051381:Rats; D011919:Rats, Inbred Strains; D012513:Sarcoma, Experimental / Q000139:chemically induced / Q000473:pathology*
D000085:Acetates; D001580:Benzopyrenes; D019342:Acetic Acid
Zur Wirkung oral applizierten Zinks auf die Metastasenbildung nach intravenöser Applikation von Zellen eines benzpyreninduzierten Rattensarkoms.