Association of peptic ulcer with Helicobacter pylori and the recurrence rate. A three year follow-up study.
Helicobacter pylori is associated with 70-100% of peptic ulcers. Relapse of infection has been shown to cause recurrences of ulcers in a large number of studies. We diagnosed 137 cases of peptic ulcer (121 DU; 16 GU) during a 3 year period. Of these, 117 were positive for H pylori. Sixty six of the 117 cases staying in the vicinity of the Hospital were followed up for a minimum period of 3 months upto a maximum period of 3 years. In 91 examinations there was relapse of H pylori infection and ulcer recurrence was seen in 58 (63%), whereas ulcer recurred only in 6 out of 61 examinations where H pylori had not relapsed (10%). The difference was highly significant by Chi square test. (P less than 0.001).
Nanivadekar
S A
SA
Department of Gastroenterology, L.T.M. Medical College, Sion, Bombay.
Sawant
P D
PD
Patel
H D
HD
Shroff
C P
CP
Popat
U R
UR
Bhatt
P P
PP
D000293:Adolescent; D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D005773:Gastroscopy; D016481:Helicobacter Infections; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000382:microbiology*; D012008:Recurrence