title: Monte Carlo modelling of light propagation in breast tissue.
abstract: Light transport in three-dimensional plane-parallel tissue slabs has been modelled by Monte Carlo analogue simulation. The model design has allowed the study of transmission properties that are pertinent to imaging systems for the detection of breast cancer. An important aspect of the investigations is that they make use of data obtained from quantitative measurements of light scattering and absorption in normal and pathological breast tissues. It is shown that an imaging technique which used a raster scanning laser and detector arrangement and plane-parallel compression of the breast could have considerable advantages in terms of improved transmittance, spatial unsharpness and contrast. Time-of-flight gating of images is also found to be beneficial provided that the light intensities after temporal filtering remain adequate.
authors.affiliation: Department of Radiodiagnosis, University of Bristol, Bristol General Hospital, UK.
authors.forename: H
authors.initials: H
authors.lastname: Key
authors.forename: E R
authors.initials: ER
authors.lastname: Davies
authors.forename: P C
authors.initials: PC
authors.lastname: Jackson
authors.forename: P N
authors.initials: PN
authors.lastname: Wells
mesh_terms: D001940:Breast; D003198:Computer Simulation; D005260:Female; D006801:Humans; D008961:Models, Structural; D009010:Monte Carlo Method; D014172:Transillumination