title: Pasteurella haemolytica is highly sensitive to ultraviolet irradiation.
abstract: The response of Pasteurella haemolytica to ultraviolet irradiation was determined. The results for survival show that P. haemolytica is very sensitive to UV-irradiation. This UV-sensitivity is similar to E. coli strains defective in UV repair mechanism(s). Analysis of the distribution of TCA insoluble versus TCA soluble [3H]thymine dimers in UV-irradiated DNA of P. haemolytica during a 2-h post-irradiation period indicates that the bacterium is deficient in an excision-repair system. These data suggest that P. haemolytica lacks some of the important mechanisms to repair UV-induced damage.
authors.affiliation: Department of Microbiology, University of Guelph, Ont., Canada.
authors.forename: R Y
authors.initials: RY
authors.lastname: Lo
authors.forename: L E
authors.initials: LE
authors.lastname: MacDonald
mesh_terms: D004260:DNA Repair; D004269:DNA, Bacterial / Q000235:genetics / Q000528:radiation effects; D007700:Kinetics; D010325:Pasteurella / Q000187:drug effects / Q000254:growth & development / Q000528:radiation effects*; D014238:Trichloroacetic Acid / Q000494:pharmacology; D014466:Ultraviolet Rays
chemical_list: D004269:DNA, Bacterial; D014238:Trichloroacetic Acid