title: Aneuploid DNA content in pancreatic adenocarcinoma.
abstract: DNA content measurements were performed by flow cytometry on eight ductal-type pancreatic adenocarcinomas. The majority of the neoplasms contained an aneuploid DNA content, with hyperdiploid DNA content being the most common abnormality. Two neoplasms had a diploid DNA content. These latter two patients are alive at 11 mo and 3 mo. The data suggest that a large percentage of pancreatic adenocarcinomas have an aneuploid DNA content. Further study is needed to evaluate the relationship between aneuploid DNA content and survival.
authors.affiliation: Department of Pathology, Medical College of Ohio, Toledo 43699.
authors.forename: T M
authors.initials: TM
authors.lastname: Wido
authors.forename: J L
authors.initials: JL
authors.lastname: Myles
authors.forename: L
authors.initials: L
authors.lastname: Pisharodi
authors.forename: T
authors.initials: T
authors.lastname: Sawyer
authors.forename: K
authors.initials: K
authors.lastname: Kim
authors.forename: A F
authors.initials: AF
authors.lastname: Gohara
authors.forename: J M
authors.initials: JM
authors.lastname: Howard
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics* / Q000401:mortality; D000782:Aneuploidy; D004273:DNA, Neoplasm / Q000032:analysis*; D006801:Humans; D010190:Pancreatic Neoplasms / Q000235:genetics* / Q000401:mortality; D011379:Prognosis
chemical_list: D004273:DNA, Neoplasm