title: [Diagnostic value of CK-MB for the determination of perioperative infarct in coronary artery bypass operation].
abstract: To assess the diagnostic value of CK-MB determinations after CABG surgery to detect or exclude perioperative myocardial infarction, 228 consecutive patients were studied with serial ECGs, as well as pre- and postoperative left heart catheterization and thallium-201-scintigraphy. CK-MB values above or below 100 U/l had a sensitivity and specificity of 73% each. There was a linear correlation between CK-MB values and total ischemic time. Thus, an increasing amount of myocardium is lost with each additional minute of ischemia despite today's methods of myocardial protection. Due to its low diagnostic accuracy CK-MB seems not to be very helpful for the diagnosis of perioperative myocardial infarction.
authors.affiliation: Abteilung für Kardiologie, DIM, Kantonsspital Basel.
authors.forename: R B
authors.initials: RB
authors.lastname: Schwendener
authors.forename: M
authors.initials: M
authors.lastname: Pfisterer
authors.forename: K
authors.initials: K
authors.lastname: Skarvan
authors.forename: P
authors.initials: P
authors.lastname: Stulz
authors.forename: E
authors.initials: E
authors.lastname: Grädel
mesh_terms: D000328:Adult; D000368:Aged; D001026:Coronary Artery Bypass; D003402:Creatine Kinase / Q000097:blood*; D005260:Female; D006801:Humans; D007527:Isoenzymes; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000201:enzymology; D011183:Postoperative Complications / Q000175:diagnosis* / Q000201:enzymology; D011446:Prospective Studies
chemical_list: D007527:Isoenzymes; D003402:Creatine Kinase
vernacular_title: Diagnostischer Wert der CK-MB zur Beurteilung des perioperativen Infarktes bei der AKB-Operation.