title: [The use of freeze fracturing in combination with light, scanning and transmission electron microscopy for studying the structure of the normal and atherosclerotically altered human aortic intima].
abstract: Three-dimensional network of smooth muscle cells (SMC) with processes was found in the subendothelial intima of human aorta. The cells were connected with each other through gap junctions. In the direction from the media to the endothelium the number of plasma membrane caveolae increased, their distribution becoming more random. In the fatty streak, the integrity of cellular network was seen destroyed. In the extracellular matrix multilamellar ball-like structures containing large intramembranous particles appeared. In the fibrous plaque, SMCs are completely isolated by connective tissue fibres.
authors.forename: M D
authors.initials: MD
authors.lastname: Rekhter
authors.forename: E R
authors.initials: ER
authors.lastname: Andreeva
authors.forename: G A
authors.initials: GA
authors.lastname: Alimov
authors.forename: A A
authors.initials: AA
authors.lastname: Mironov
authors.forename: A N
authors.initials: AN
authors.lastname: Orekhov
mesh_terms: D001013:Aorta, Thoracic / Q000648:ultrastructure*; D001018:Aortic Diseases / Q000473:pathology*; D001161:Arteriosclerosis / Q000473:pathology*; D005614:Freeze Fracturing; D006801:Humans; D008853:Microscopy; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning
vernacular_title: Ispol'zovanie zamorazhivaniia--skalyvaniia v komplekse so svetovoĭ, skaniruiushcheĭ i transmissionnoĭ élektronnoĭ mikroskopieĭ dlia issledovaniia struktury normal'noĭ i aterosleroticheski izmenennoĭ intimy aorty cheloveka.