Studies with human, baboon, and vervet monkey chorionic gonadotrophins.
Vervet monkey, baboon, and human chorionic gonadotrophin(CG) were partially purified and their activity was monitored using radioimmuno- and radioreceptor-assays. They showed similar behaviour during ion exchange chromatography and isoelectric focusing and had isoelectric points between pH 4.50 and 5.13. The Stokes' radii were 32A, 34A, and 33A for vervet monkey, baboon, and human CG, respectively. Corresponding immunoassay potencies were 476.9, 1,143.1, and 9,600 IU/mg, while the bioassay estimates were 491.7, 997.8, and 8,950.0 IU/mg.
Mwenda
J M
JM
Institute of Primate Research, National Museums of Kenya, Nairobi.
Bambra
C S
CS
Tarara
R P
RP
D000704:Analysis of Variance; D000818:Animals; D001667:Binding, Competitive; D002522:Chlorocebus aethiops / Q000378:metabolism*; D006063:Chorionic Gonadotropin / Q000737:chemistry*; D002848:Chromatography, DEAE-Cellulose; D002850:Chromatography, Gel; D002852:Chromatography, Ion Exchange; D005260:Female; D006801:Humans; D007525:Isoelectric Focusing; D010215:Papio / Q000378:metabolism*; D011247:Pregnancy; D011863:Radioimmunoassay; D011869:Radioligand Assay; D012044:Regression Analysis
D006063:Chorionic Gonadotropin