title: [Thiophene as a structural element in physiologically active substances. 18. A thiophene analog of propafenone].
abstract: The preparation of compounds 1, which are thiophene analogues of propafenon (A) is described. Compound 1a shows antiarrhythmic activity in various in vivo test-systems.
authors.affiliation: Institut für Organische Chemie, Technischen Universität, Wien.
authors.forename: D
authors.initials: D
authors.lastname: Binder
authors.forename: C R
authors.initials: CR
authors.lastname: Noe
authors.forename: W
authors.initials: W
authors.lastname: Holzer
mesh_terms: D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000138:chemical synthesis*; D051379:Mice; D011405:Propafenone / Q000031:analogs & derivatives* / Q000494:pharmacology; D051381:Rats; D013876:Thiophenes / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000889:Anti-Arrhythmia Agents; D013876:Thiophenes; D011405:Propafenone
vernacular_title: Thiophen als Strukturelement physiologisch aktiver Substanzen, 18. Mitt.: Ein Thiophenanalogon des Propafenons.