[Nuclear DNA content and morphological parameters in laryngeal papillomas and carcinomas].
The nuclear DNA content and morphological parameters were measured in 27 laryngeal papilloma (LP) and 64 laryngeal carcinoma (LC) specimens by image analysis technique. Results showed that the DNA contents between LC and control group (P less than 0.01) and that between LP and control group (P less than 0.05) were significantly different. The peak value of control group was 2C and that of LP 3C. The histogram of LC showed double peaks at 3C and 6C. The morphological parameters differed significantly among the above three groups (P less than 0.01). The data confirm that LP is an epithelial borderline tumor.
Wang
J
J
Xijing Hospital, 4th Military Medical University of PLA, Xian.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000782:Aneuploidy; D002294:Carcinoma, Squamous Cell / Q000235:genetics / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D004247:DNA / Q000032:analysis; D004273:DNA, Neoplasm / Q000032:analysis*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007822:Laryngeal Neoplasms / Q000235:genetics* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010212:Papilloma / Q000235:genetics* / Q000473:pathology
D004273:DNA, Neoplasm; D004247:DNA