Effects of catabolic and anabolic cytokines on proteoglycan biosynthesis in young, old and osteoarthritic canine cartilage.
Venn
G
G
Department of Biochemistry, Kennedy Institute of Rheumatology, London, U.K.
Lauder
R M
RM
Hardingham
T E
TE
Muir
H
H
D000375:Aging; D000818:Animals; D000831:Animals, Newborn; D002358:Cartilage, Articular / Q000254:growth & development / Q000378:metabolism*; D016207:Cytokines / Q000494:pharmacology*; D004285:Dogs; D006025:Glycosaminoglycans / Q000096:biosynthesis; D007334:Insulin-Like Growth Factor I / Q000494:pharmacology; D007375:Interleukin-1 / Q000494:pharmacology; D007700:Kinetics; D010003:Osteoarthritis / Q000378:metabolism*; D011509:Proteoglycans / Q000096:biosynthesis*; D011994:Recombinant Proteins / Q000494:pharmacology; D016212:Transforming Growth Factor beta / Q000494:pharmacology; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology
D016207:Cytokines; D006025:Glycosaminoglycans; D007375:Interleukin-1; D011509:Proteoglycans; D011994:Recombinant Proteins; D016212:Transforming Growth Factor beta; D014409:Tumor Necrosis Factor-alpha; D007334:Insulin-Like Growth Factor I