title: [FSH, LH, prolactin, estradiol and progesterone after burn injuries in premenopausal and postmenopausal women].
abstract: The authors examined 49 women who suffered severe burns and had to be hospitalized. Thirteen of these women were postmenopausal, 35 premenopausal and in one women, incipient pregnancy was revealed. In 14 women repeatedly FSH, LH oestradiol, progesterone and prolactin were assessed in serum by RIA. The group of premenopausal and postmenopausal women did not differ as to the levels of oestradiol, progesterone and prolactin. The gonadotropin levels in postmenopausal women were somewhat higher but the difference was significant only in FSH. The mean levels of the investigated hormones in premenopausal and postmenopausal women were: FSH 7.98 and 21.56 mIU/ml resp. oestradiol 151.88 and 183 micrograms/ml) resp. These differences cannot be explained by possible differences in the extent of burns or the time when the serum sample was taken. The authors interpret the results to the effect that the adrenals and steroid hormones produced by them resp. have a central position in the dysfunction of the pituitary-ovarian axis. These hormones influence by a backfeed mechanism the secretion of pituitary gonadotropins. This is consistent with data in the literature dealing with burns in men.
authors.affiliation: Ustav pro péci o matku a dítĕ, Praha-Podolí.
authors.forename: P
authors.initials: P
authors.lastname: Cepický
authors.forename: S
authors.initials: S
authors.lastname: Bucek
authors.forename: R
authors.initials: R
authors.lastname: Königová
authors.forename: A
authors.initials: A
authors.lastname: Stroufová
authors.forename: R
authors.initials: R
authors.lastname: Uzel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002056:Burns / Q000097:blood*; D004958:Estradiol / Q000097:blood*; D005260:Female; D006065:Gonadotropins, Pituitary / Q000097:blood*; D006801:Humans; D008593:Menopause / Q000097:blood*; D008875:Middle Aged; D011374:Progesterone / Q000097:blood*
chemical_list: D006065:Gonadotropins, Pituitary; D011374:Progesterone; D004958:Estradiol
vernacular_title: FSH, LH, prolaktin, estradiol a progesteron po popáleninovém traumatu u premenopauzálních a postmenopauzálních zen.