title: Structures and cytotoxic activity relationship of casearins, new clerodane diterpenes from Casearia sylvestris Sw.
abstract: Casearins G-R, new cytotoxic clerodane diterpenes have been isolated from the leaves of Casearia sylvestris Sw. (Flacourtiaceae). Their structures have been elucidated by spectroscopic methods and chemical conversions, and their structure-activity relationships have been discussed.
authors.affiliation: Department of Pharmacognosy, Tokyo College of Pharmacy, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Morita
authors.forename: M
authors.initials: M
authors.lastname: Nakayama
authors.forename: H
authors.initials: H
authors.lastname: Kojima
authors.forename: K
authors.initials: K
authors.lastname: Takeya
authors.forename: H
authors.initials: H
authors.lastname: Itokawa
authors.forename: E P
authors.initials: EP
authors.lastname: Schenkel
authors.forename: M
authors.initials: M
authors.lastname: Motidome
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry*; D002460:Cell Line; D004224:Diterpenes / Q000737:chemistry* / Q000494:pharmacology; D010946:Plants, Medicinal / Q000032:analysis*; D013329:Structure-Activity Relationship
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004224:Diterpenes