Inhibition of hematopoietic stem cell proliferation by hemoregulatory peptide pyroGlu-Glu-Asp-Cys-Lys (pEEDCK) provides protection against short-term neutropenia and long-term damage.
Paukovits
W R
WR
Laboratory of Growth Regulation, University of Vienna, Vienna, Austria.
Moser
M H
MH
Rutter
R
R
Paukovits
J B
JB
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D003114:Colony-Forming Units Assay; D003561:Cytarabine / Q000633:toxicity; D006131:Growth Inhibitors / Q000494:pharmacology*; D006410:Hematopoiesis / Q000187:drug effects / Q000502:physiology; D006412:Hematopoietic Stem Cells / Q000166:cytology* / Q000187:drug effects; D007700:Kinetics; D051379:Mice; D008807:Mice, Inbred BALB C; D009503:Neutropenia / Q000139:chemically induced / Q000517:prevention & control*; D009842:Oligopeptides / Q000494:pharmacology* / Q000627:therapeutic use; D011761:Pyrrolidonecarboxylic Acid / Q000031:analogs & derivatives
D006131:Growth Inhibitors; D009842:Oligopeptides; D003561:Cytarabine; C040758:hemoregulatory peptide 5b; D011761:Pyrrolidonecarboxylic Acid