Dynamic and equilibrium swelling behaviour of pH-sensitive hydrogels containing 2-hydroxyethyl methacrylate.
The equilibrium and dynamic swelling behaviour of hydrogels containing methacrylic acid or various acrylamides was studied as a function of copolymer composition. In all cases, the comonomer was 2-hydroxyethyl methacrylate, methyl methacrylate or N-vinyl-2-pyrrolidone. It is shown that pH-sensitive behaviour with a wide range of swelling ratios could be obtained using a range of compositional changes. The dynamic swelling behaviour was a function of the acidity of the buffered solution.
Brannon-Peppas
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School of Chemical Engineering, Purdue University, West Lafayette, IN 47907.
Peppas
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D002021:Buffers; D003102:Colloids / Q000737:chemistry; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D006863:Hydrogen-Ion Concentration; D008689:Methacrylates / Q000737:chemistry*; D020366:Methylmethacrylate; D008768:Methylmethacrylates / Q000737:chemistry; D008970:Molecular Weight; D011092:Polyethylene Glycols / Q000737:chemistry*; D011760:Pyrrolidinones / Q000737:chemistry
D002021:Buffers; D003102:Colloids; D008689:Methacrylates; D008768:Methylmethacrylates; D011760:Pyrrolidinones; D020366:Methylmethacrylate; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D011092:Polyethylene Glycols; C005044:hydroxyethyl methacrylate; C042670:N-vinyl-2-pyrrolidinone