The discovery and biologic properties of cephalosporin-based inhibitors of PMN elastase.
Davies
P
P
Department of Immunology & Inflammation, Merck Sharp & Dohme Research Laboratories, Rahway, New Jersey 07065.
Ashe
B M
BM
Bonney
R J
RJ
Dorn
C
C
Finke
P
P
Fletcher
D
D
Hanlon
W A
WA
Humes
J L
JL
Maycock
A
A
Mumford
R A
RA
D002511:Cephalosporins / Q000494:pharmacology*; D006801:Humans; D019272:Leukocyte Elastase; D010196:Pancreatic Elastase / Q000037:antagonists & inhibitors* / Q000502:physiology; D011759:Pyrrolidines / Q000494:pharmacology*
D002511:Cephalosporins; D011759:Pyrrolidines; C065332:L 658758; C059583:L 659286; D010196:Pancreatic Elastase; D019272:Leukocyte Elastase