title: Surgical implications of cerebral dysgenesis.
abstract: Cerebral dysgenesis encompasses varied disorders of brain development. Based on the understanding of these conditions provided by histopathologists, embryologists, radiologists and developmental pediatricians, surgeons are able to appropriately assist in the care of these patients. The surgeon can offer assessment of the ventriculomegaly that commonly accompanies cerebral dysgenesis in addition to providing methods to control hydrocephalus, to reconstruct cranial and facial malformations and to remove dysfunctional tissue. For most patients, surgical intervention is only one of the many factors that determine developmental prognosis. Based on the foundation built by other specialists, this review discusses cerebral dysgenesis from the perspective of historical and current surgical interventions.
authors.affiliation: Department of Surgery, University of British Columbia, Vancouver, Canada.
authors.forename: D D
authors.initials: DD
authors.lastname: Cochrane
authors.forename: K J
authors.initials: KJ
authors.lastname: Poskitt
authors.forename: M G
authors.initials: MG
authors.lastname: Norman
mesh_terms: D001921:Brain / Q000002:abnormalities* / Q000254:growth & development; D001927:Brain Diseases / Q000601:surgery*; D005147:Facial Bones / Q000002:abnormalities / Q000601:surgery; D006801:Humans; D012886:Skull / Q000002:abnormalities / Q000601:surgery