title: [Protective effect of hyperbaric hypoxygenation for paraquat poisoning in the rat].
abstract: The effect to paraquat in normobaric conditions and hyperbaric conditions with either a normal or low (10%) oxygen percentage was investigated in rats. Results showed that hyperbaric conditions increased the toxic effect of paraquat on the lung. By contrast, in hypoxic-hyperbaric conditions, the toxic effect of paraquat was decreased either clinically or macro-/microscopically, and lung injury was reduced.
authors.affiliation: Service d'Anesthésiologie et Réanimation Hôpital S. Camillo, U.L.S. RM10, Rome, Italie.
authors.forename: R
authors.initials: R
authors.lastname: Manieri
authors.forename: R
authors.initials: R
authors.lastname: Bronzi
authors.forename: A
authors.initials: A
authors.lastname: Grilli
authors.forename: B
authors.initials: B
authors.lastname: Loffredo
authors.forename: P G
authors.initials: PG
authors.lastname: Data
authors.forename: L
authors.initials: L
authors.lastname: Napolitano
authors.forename: M
authors.initials: M
authors.lastname: Felaco
mesh_terms: D000818:Animals; D001274:Atmospheric Pressure; D008168:Lung / Q000473:pathology; D009584:Nitrogen / Q000008:administration & dosage; D010100:Oxygen / Q000008:administration & dosage*; D010269:Paraquat / Q000506:poisoning*; D011041:Poisoning / Q000628:therapy; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D009584:Nitrogen; D010269:Paraquat; D010100:Oxygen
vernacular_title: Effet protecteur de l'hypoxygénation hyperbarique au cours de l'intoxication par le paraquat, chez le rat.