[An immunohistochemical study of vitreal and epiretinal membranes in human eyes].
Macrophages, monocytes and the expression of HLA-DR antigen in 52 cases of various vitreal and epiretinal membranes in human eyes were studied with the immunohistochemical technique. The results showed that more than 80% of the specimens were macrophage positive and expressed HLA-DR antigen, and monocytes were mainly seen in the specimens of proliferative diabetic retinopathy (41.7%). Macrophages were considered to play an important role in the development of epiretinal membranes, and immuno-response was also one of the related factors.
Tang
S B
SB
Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou.
Scheiffarth
O F
OF
D000911:Antibodies, Monoclonal / Q000032:analysis; D003930:Diabetic Retinopathy / Q000276:immunology / Q000378:metabolism*; D006684:HLA-DR Antigens / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D008264:Macrophages / Q000276:immunology; D009000:Monocytes / Q000276:immunology; D012160:Retina / Q000473:pathology; D012173:Retinitis / Q000276:immunology / Q000378:metabolism*
D000911:Antibodies, Monoclonal; D006684:HLA-DR Antigens