Phagocytosis of human erythrocytes by Naegleria is not related to species pathogenicity. A phase-contrast cinemicrographic study.
This phase contrast cinemicrographic study evaluated the phagocytic activity of Naegleria spp. (Naegleria fowleri, Naegleria australiensis and Naegleria lovaniensis) towards human red cells. Thus erythrophagocytosis, a marker of pathogeneicity for Entamoeba histolytica, did not correlate with virulence in either the pathogenic or non-pathogenic Naegleria spp. tested. Our study also revealed no quantitative differences in phagocytosis by Naegleria spp. of human erythrocytes.
Scaglia
M
M
Department of Infectious Diseases, University IRCCS San Matteo, Pavia, Italy.
Gatti
S
S
Brustia
R
R
Chichino
G
G
Rondanelli
E G
EG
D000818:Animals; D002633:Chemotaxis; D004912:Erythrocytes; D006461:Hemolysis; D006801:Humans; D008858:Microscopy, Phase-Contrast; D009040:Motion Pictures; D009253:Naegleria / Q000472:pathogenicity* / Q000502:physiology; D010587:Phagocytosis; D011554:Pseudopodia / Q000502:physiology; D014774:Virulence