DMSO induces the formation of microfilament bundles in nuclei of zoospores of Phytophthora infestans (Mont.) De Bary (Oomycetes, Pythiaceae).
Cytoskeletons of zoospores of the fungus Phytophthora infestans (Mont.) De Bary treated with dimethylsulfoxide (DMSO) were studied by electron microscopy. High concentrations of DMSO (greater than or equal to 5%) resulted in lysis of the cells and disturbances of the microtubule pattern of flagellar axonemes. Treatment with low concentrations of DMSO (1%-0.1%) induced the formation of bundled intranuclear filaments. It is assumed that these filament bundles should consist of F-actin.
Jelke
E
E
Central Institute of Microbiology and Experimental Therapy, Academy of Sciences of the GDR, Jena.
Oertel
B
B
D008841:Actin Cytoskeleton / Q000187:drug effects / Q000648:ultrastructure*; D002467:Cell Nucleus / Q000187:drug effects / Q000648:ultrastructure*; D004121:Dimethyl Sulfoxide / Q000494:pharmacology*; D008854:Microscopy, Electron; D010838:Phytophthora / Q000187:drug effects / Q000502:physiology / Q000648:ultrastructure*; D013172:Spores, Fungal / Q000187:drug effects / Q000648:ultrastructure
D004121:Dimethyl Sulfoxide