[The correlation of the indices of humoral immunity and of the activity of the renin-angiotensin-aldosterone system in hypertensive patients].
The content of IgA, IgM, IgG and IgE was measured in 55 male patients with uncomplicated essential hypertension (EH) running a labile course (25 patients) and a stable course (30 patients). Analyzing the material, account was taken of aggravated heredity factor as regards arterial hypertension, established according to the anamnesis in relatives of the first degree kinship. A group of patients with the aggravated familial anamnesis as regards arterial hypertension were distinguished. They suffered from labile hypertension with a tendency to hyperreninemia and IgE overproduction, which may be unfavourable in terms of EH progression and development of cardiovascular complications.
Vil'chinskaia
M Iu
MIu
Zharova
E A
EA
Nasonov
E L
EL
Bosykh
E G
EG
D000328:Adult; D000450:Aldosterone / Q000097:blood; D000804:Angiotensin II / Q000097:blood; D000917:Antibody Formation; D004198:Disease Susceptibility / Q000097:blood / Q000276:immunology; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000276:immunology*; D007136:Immunoglobulins / Q000032:analysis; D008297:Male; D012083:Renin / Q000097:blood; D012084:Renin-Angiotensin System / Q000502:physiology*
D007136:Immunoglobulins; D000804:Angiotensin II; D000450:Aldosterone; D012083:Renin
Sootnoshenie pokazateleĭ gumoral'nogo immuniteta i aktivnosti renin-angiotenzin-al'dosteronovoĭ sistemy u bol'nykh gipertonicheskoĭ bolezn'iu.