title: [Moradol (butorphanol tartrate) as the analgesic component of current combination general anesthesia].
abstract: A technique is described for the use of moradol as an agent ensuring analgesia in modern combined general anesthesia during abdominal and thoracic surgery, cardiac surgery, cardiopulmonary bypass included, and diagnostic manipulations. Moradol was particularly effective for long-term surgery. The drug was also useful for premedication (0.06 mg/kg) and needed no combination with any tranquilizers or analgesics. Agonist opioid activity of moradol was maximum 10 min after its intravenous administration, therefore a 5 to 10 min exposition upon moradol injection prior to hypnotic drug administration is suggested. Bolus drug dose (150 mg/kg) for induction to anesthesia was an adequate protection against pain impulsation in surgical trauma in the course of 3-4 hours of surgical intervention.
authors.forename: M Ia
authors.initials: MIa
authors.lastname: Avrutskiĭ
authors.forename: V S
authors.initials: VS
authors.lastname: Shiriaev
authors.forename: A V
authors.initials: AV
authors.lastname: Machulin
mesh_terms: D000328:Adult; D000368:Aged; D000700:Analgesics; D000768:Anesthesia, General; D002077:Butorphanol; D006801:Humans; D008875:Middle Aged; D013514:Surgical Procedures, Operative
chemical_list: D000700:Analgesics; D002077:Butorphanol
vernacular_title: Moradol (butorfanol-tartrat) v kachestve sredstva, obespechivaiushchego analgeticheskiĭ komponent sovremennoĭ kombinirovannoĭ obshcheĭ anestezii.