[A pharmacodynamic investigation of the effect of polyholozidic substances extracted from Plantago sp. on the digestive tract].
From the leaves and seeds of some Plantago species (Plantago major, media, lanceolata) the polyholozidic fraction was separated. A statistically significant gastroprotective action was found both in the case of the polyholozide obtained from seeds and leaves in two experimental models. At higher doses a laxative action was also obtained.
Hriscu
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Facultatea de farmacie, Disciplina de farmacodinamie, Institutul de Medicină şi Farmacie Iaşi.
Stănescu
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Ionescu
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Verbuţă
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D000818:Animals; D000897:Anti-Ulcer Agents / Q000494:pharmacology* / Q000627:therapeutic use; D001241:Aspirin; D002400:Cathartics / Q000494:pharmacology* / Q000627:therapeutic use; D004353:Drug Evaluation, Preclinical; D000431:Ethanol; D005769:Gastrointestinal Motility / Q000187:drug effects; D005772:Gastrointestinal Transit / Q000187:drug effects; D007213:Indomethacin / Q000627:therapeutic use; D010936:Plant Extracts / Q000494:pharmacology* / Q000627:therapeutic use; D010943:Plantago; D010946:Plants, Medicinal; D051381:Rats; D013276:Stomach Ulcer / Q000139:chemically induced / Q000188:drug therapy
D000897:Anti-Ulcer Agents; D002400:Cathartics; D010936:Plant Extracts; D000431:Ethanol; D001241:Aspirin; D007213:Indomethacin
Investigarea farmacodinamică a influenţei substanţelor poliholozidice extrase din Plantago sp. asupra tractului digestiv.