[Change in myocardial phospholipid composition in cardiac hyperfunction as one of the possible prerequisites of sudden death].
It is shown that additional load on a compensatory hypertrophied heart disturbs its adaptation mechanisms. Lipid peroxidation is activated, the amount of some types of unsaturated phospholipids reduces, and lysophospholipids, detergents damaging the cell membranes and causing an arrhythmogenic effect accumulate.
Khanina
N Ia
NIa
Bel'chenko
D I
DI
D000818:Animals; D003645:Death, Sudden / Q000209:etiology*; D006331:Heart Diseases / Q000150:complications / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism*; D010743:Phospholipids / Q000378:metabolism*; D051381:Rats
D010743:Phospholipids
Izmenenie fosfolipidnogo sostava miokarda pri giperfuktsii serdtsa kak odna iz vozmozhnykh metabolicheskikh predposyok vnezapnoĭ smerti.