[Thiocyanate--a pathogenetic factor in cystic fibrosis (mucoviscidosis)?].
Thiocyanate (SCN-) concentrations in serum samples of 32 cystic fibrosis (CF) patients, 30 controls as well as 23 heterozygotes (parents of CF patients) were investigated, because SCN- influenced viscosity of secretions, membrane functions as well as nonspecific and specific defense processes. CF patients showed little smaller SCN- serum levels, but the differences were not statistically significant. There were remarkable smaller values for CF patients with most serious clinical conditions due to severe pulmonary changes.
Weuffen
W
W
Hygieneinstitut Greifswald, Universität Rostock.
Hein
J
J
Below
H
H
Gülzow
H U
HU
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000097:blood* / Q000175:diagnosis / Q000235:genetics; D006580:Genetic Carrier Screening; D006801:Humans; D008168:Lung / Q000473:pathology; D011379:Prognosis; D013861:Thiocyanates / Q000097:blood*
D013861:Thiocyanates; C031760:thiocyanate
Thiocyanat--ein pathogenetischer Faktor bei der zystischen Fibrose (Mukoviszidose)?