title: [Transsphenoidal approach to pituitary tumors].
abstract: Over the past 2 years 44 patients with pituitary tumors underwent transsphenoidal resection. A specialized team performed the procedure so as to optimize the results. 20 patients had nonsecreting macroadenomas and 24 suffered from hormone-secreting adenomas. All who presented with visual deterioration had improved vision after operation. Only 3 developed new endocrine deficits following surgery, while in 4 with invasive prolactinoma vision improved following surgery but hyperprolactinemia persisted. 8 of 11 patients with acromegaly were cured, while in the other 3, who had invasive tumors, growth hormone decreased significantly. 8 of 9 patients with Cushing's disease were cured. In only 1 case did a permanent complication, diabetes insipidus, occur; there was no mortality. These results demonstrate the efficacy of the procedure and the advantages of a dedicated team.
authors.affiliation: Dept. of Neurosurgery, Hadassah-University Hospital, Jerusalem.
authors.forename: Z H
authors.initials: ZH
authors.lastname: Rappaport
authors.forename: B
authors.initials: B
authors.lastname: Glazer
authors.forename: E
authors.initials: E
authors.lastname: Ashkenazy
authors.forename: M N
authors.initials: MN
authors.lastname: Shalit
mesh_terms: D000236:Adenoma / Q000601:surgery*; D003919:Diabetes Insipidus / Q000209:etiology; D006801:Humans; D008722:Methods; D010348:Patient Care Team; D010911:Pituitary Neoplasms / Q000601:surgery*; D011183:Postoperative Complications; D015175:Prolactinoma / Q000601:surgery*