title: [Chemical studies on polysaccharide of Achyeanthes bidentata].
abstract: A peptide-polysaccharide, ABAB showing immunological activity was isolated from Achyeanthes bidentata Bl. It was shown to be homogeneous by HPLC and optical rotation analysis. Its molecular weight was estimated to be 2.3 x 10(4). It composed of D-glucuronic acid, D-galactose, D-galacturonic acid, L-arabinose and L-rhamnose in molar ratio of 12:2:3:1:1. Reduction of carboxyl groups, methylation analysis, periodate oxidation, Smith degradation and IR analysis showed that ABAB possesses a main chain composed of (1----4)-D-glucuronic acid and (1----4)-D-galacturonic acid residues. The non-reducing terminal residues in the side chains were L-arabinose and L-rhamnose. ABAB contained 24.1% of peptides composed of glycine, glutamic acid, aspartic acid and serine.
authors.affiliation: Shanghai Institute of Materia Medica Academia Sinica.
authors.forename: J N
authors.initials: JN
authors.lastname: Fang
authors.forename: Z H
authors.initials: ZH
authors.lastname: Zhang
authors.forename: B N
authors.initials: BN
authors.lastname: Liu
mesh_terms: D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D008970:Molecular Weight; D010946:Plants, Medicinal / Q000032:analysis*; D011134:Polysaccharides / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D004365:Drugs, Chinese Herbal; D011134:Polysaccharides