title: Nabumetone. Evidence for the lack of enterohepatic circulation of the active metabolite 6-MNA in humans.
authors.affiliation: Clinical Pharmacology Research Institute, Beecham-Wülfing GmbH & Co KG, Neuss, Federal Republic of Germany.
authors.forename: M A
authors.initials: MA
authors.lastname: Brett
authors.forename: G
authors.initials: G
authors.lastname: Buscher
authors.forename: E
authors.initials: E
authors.lastname: Ellrich
authors.forename: W H
authors.initials: WH
authors.lastname: Greb
authors.forename: H J
authors.initials: HJ
authors.lastname: Kurth
authors.forename: G
authors.initials: G
authors.lastname: Rülander
authors.forename: B
authors.initials: B
authors.lastname: Schmerenbeck
authors.forename: R E
authors.initials: RE
authors.lastname: Haddock
authors.forename: A R
authors.initials: AR
authors.lastname: Thawley
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000378:metabolism* / Q000494:pharmacology; D002074:Butanones / Q000378:metabolism* / Q000494:pharmacology; D002792:Cholestyramine Resin / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D004311:Double-Blind Method; D004764:Enterohepatic Circulation / Q000187:drug effects*; D006207:Half-Life; D006801:Humans; D008297:Male; D000077430:Nabumetone; D009280:Naphthaleneacetic Acids / Q000097:blood / Q000378:metabolism* / Q000493:pharmacokinetics
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D002074:Butanones; D009280:Naphthaleneacetic Acids; D002792:Cholestyramine Resin; C044612:6-methoxy-2-naphthylacetic acid; D000077430:Nabumetone