title: Serum amyloid A levels in acute graft-versus-host disease in bone marrow transplant recipients.
abstract: We studied serum amyloid A levels of 31 bone marrow transplant recipients with and without acute graft-versus-host disease. Before transplantation the mean SAA concentration was 5.1 +/- 0.8 mg/l (mean +/- SEM). It remained low in patients with no signs of aGVHD but increased significantly during aGVHD to 54.0 +/- 8.2 mg/l (p less than 0.001 compared to pre-BMT value). Severe infections also induced high SAA levels.
authors.affiliation: Transplantation Laboratory, University of Helsinki, Finland.
authors.forename: R
authors.initials: R
authors.lastname: Leskinen
authors.forename: C P
authors.initials: CP
authors.lastname: Maury
authors.forename: A M
authors.initials: AM
authors.lastname: Teppo
authors.forename: L
authors.initials: L
authors.lastname: Volin
authors.forename: T
authors.initials: T
authors.lastname: Ruutu
authors.forename: P
authors.initials: P
authors.lastname: Häyry
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D016026:Bone Marrow Transplantation / Q000276:immunology*; D006086:Graft vs Host Disease / Q000097:blood* / Q000188:drug therapy; D006801:Humans; D000685:Serum Amyloid A Protein / Q000032:analysis*
chemical_list: D000305:Adrenal Cortex Hormones; D000685:Serum Amyloid A Protein