Synthesis and antimicrobiological activity of N-aryl-substituted 2-methyl-3-carbethoxy-5-pyrrolinone derivatives.
We describe the synthesis of N-aryl-2-methyl-3-carbethoxy-5-pyrrolinones benzylidene derivatives, their condensation with azomethines and substitution with aniline. The compounds have been tested for antimicrobial and fungicide activity: they have better fungicidal than bactericidal activity.
Lovren
F
F
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sarajevo, Yugoslavia.
Gaon
I D
ID
Bobarević
B
B
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis*; D001419:Bacteria / Q000187:drug effects; D001555:Benzene Derivatives / Q000138:chemical synthesis* / Q000494:pharmacology; D002175:Candida / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011760:Pyrrolidinones / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D001555:Benzene Derivatives; D011760:Pyrrolidinones