Medial vestibular nucleus in the guinea-pig. I. Intrinsic membrane properties in brainstem slices.
Intracellular recordings were obtained from medial vestibular nuclei neurones (MVNn) in guinea-pig brainstem slices. Two main distinct neuronal classes were encountered. Type A MVNn (32.3%) were characterized by a broad action potential followed by a deep single afterhyperpolarization, a transient A-like rectification, and a single range of firing in response to current injection. Type B MVNn (47.1%), in contrast, were distinguished by the presence of a thin action potential followed first by a fast and then by a delayed and slower afterhyperpolarization. In addition, they displayed a secondary range of firing in their response to current injection. A majority of B MVNn also had either sub-threshold plateau potentials or low threshold spike bursts or a combination thereof. A third, non-homogeneous class of cells, could not be fitted into either one of the two main classes (20.6%, type C MVNn).
Serafin
M
M
Département de Physiologie, CMU, Genève, Switzerland.
de Waele
C
C
Khateb
A
A
Vidal
P P
PP
Mühlethaler
M
M
D000200:Action Potentials; D000818:Animals; D001933:Brain Stem / Q000033:anatomy & histology / Q000502:physiology*; D002462:Cell Membrane / Q000502:physiology; D005071:Evoked Potentials; D006168:Guinea Pigs; D066298:In Vitro Techniques; D009474:Neurons / Q000502:physiology*; D014726:Vestibular Nuclei / Q000033:anatomy & histology / Q000502:physiology*