Acetaminophen and protein thiol modification.
Nelson
S D
SD
Department of Medicinal Chemistry, University of Washington, Seattle 98195.
Tirmenstein
M A
MA
Rashed
M S
MS
Myers
T G
TG
D000082:Acetaminophen / Q000378:metabolism / Q000633:toxicity*; D000083:Acetanilides / Q000378:metabolism / Q000633:toxicity; D000818:Animals; D016227:Benzoquinones / Q000378:metabolism; D001665:Binding Sites; D005978:Glutathione / Q000378:metabolism; D007097:Imines / Q000378:metabolism; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D051379:Mice; D011506:Proteins / Q000378:metabolism*; D013438:Sulfhydryl Compounds / Q000378:metabolism
D000083:Acetanilides; D016227:Benzoquinones; D007097:Imines; D011506:Proteins; D013438:Sulfhydryl Compounds; D000082:Acetaminophen; C026137:3-hydroxyacetanilide; C028473:N-acetyl-4-benzoquinoneimine; D005978:Glutathione