[Treatment of nephrotic syndrome with cyclosporin A].
The authors treated eight children with corticoid dependent syndrome caused by minor abnormalities of the glomeruli with Cyclosporin A. They administered Cyclosporin, 5 mg/kg/24 h., for a period of 8-16 weeks. In three patients they used Cyclosporin A alone, 5 children were given in addition 10 mg Prednisone per day. They achieved complete remission in all patients. During treatment they monitored haematological and biochemical parameters as well as Cyclosporin A levels; before treatment and after its termination they examined also immunological indicators. They did not observe any serious side effects of treatment.
Furková
K
K
Detská klinika NsP Akademika L. Dérera, Bratislava.
Kaiserová
E
E
Páleníková
O
O
Hruskovic
I
I
Slugen
I
I
Arpasová
D
D
Janota
S
S
Nyulassy
S
S
D002648:Child; D002675:Child, Preschool; D003524:Cyclosporins / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D009404:Nephrotic Syndrome / Q000188:drug therapy* / Q000276:immunology / Q000503:physiopathology
D003524:Cyclosporins
Liecba nefrotického syndrómu cyklosporínom A.