Clonazepam in neonatal seizures: dose regimens and therapeutic efficacy.
The attempt has been made to define the optimal dose regimen of clonazepam in newborns suffering from neonatal convulsions. Results obtained from 22 patients (GA 28-41 weeks; PNA 4 h to 23 days) indicated that a dose of 0.1 mg/kg every 24 h was satisfactory in the majority of the patients. It is recommended as a starting regimen.
André
M
M
Service de Médecine Néonatale, Maternité Régionale A. Pinard, Nancy, France.
Boutroy
M J
MJ
Bianchetti
G
G
Vert
P
P
Morselli
P L
PL
D001238:Asphyxia Neonatorum / Q000150:complications; D002543:Cerebral Hemorrhage / Q000150:complications; D002998:Clonazepam / Q000097:blood / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000097:blood / Q000188:drug therapy; D007239:Infections / Q000150:complications; D008297:Male; D012640:Seizures / Q000188:drug therapy* / Q000209:etiology
D002998:Clonazepam