title: [Cholestatic jaundice complicating lipomatous pseudo-hypertrophy of the pancreas].
abstract: The authors describe a major pancreatic lipomatous infiltration, causing a "pseudo-hypertrophy" of the pancreas, in a 70-year-old man. This lesion was responsible of a hyperechogenic area at ultrasonography and of an empty pancreatic bed ("vanishing pancreas") at computed tomography, suggesting lipomatosis. This entity is a special modality of senescence of pancreatic tissue whose origin remains obscure. The progressive atrophy of the acinar lobules and the islets of Langerhans was finally responsible of a mild degree of malabsorption and of diabetes type II. The compression of the main bile duct by the enlarged lipomatous pancreas, demonstrated by percutaneous cholangiography, caused a cholestatic jaundice with abdominal pain, which was treated by a surgical derivation (hepatico-duodenostomy). This is the first description of a lipomatous pseudohypertrophy of the pancreas causing an obstruction of the common bile duct.
authors.affiliation: Service de Médecine Interne, Clinique Saint-Joseph, Mons, Belgique.
authors.forename: A
authors.initials: A
authors.lastname: Henkinbrant
authors.forename: W
authors.initials: W
authors.lastname: Khalek
authors.forename: E
authors.initials: E
authors.lastname: Farchakh
authors.forename: M
authors.initials: M
authors.lastname: Henry
mesh_terms: D000368:Aged; D002758:Cholangiography; D002760:Cholangiopancreatography, Endoscopic Retrograde; D002779:Cholestasis / Q000209:etiology*; D006801:Humans; D006984:Hypertrophy; D008068:Lipomatosis / Q000150:complications*; D008297:Male; D010179:Pancreas / Q000473:pathology; D010182:Pancreatic Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed
vernacular_title: Ictère choléstatique compliquant une pseudo-hypertrophie lipomateuse du pancréas.