[Chorioretinitis in congenital toxoplasmosis].
The goal of this study was to establish the incidence of chorioretinitis in 100 infants whose mothers presented a seroconversion during the pregnancy. It is a retrospective study over 6.5 years. There were 17 cases of latent congenital toxoplasmosis (56.7%) and 13 cases of clinical congenital toxoplasmosis (43.3%). Three infants presented with chorioretinitis: one at birth in a context of general stroke, the two others at 2 and 17 months after birth, despite treatment. The risk of retinochorioditis was the same in the case of latent or clinical congenital toxoplasmosis. The fall in the antibody titre was not a good criterion of cure; the percentage of lymphocytes in the cerebrospinal fluid could constitute a better criterion. This study confirmed the efficacy of systemic treatment of congenital toxoplasmosis.
Bazard
M C
MC
Service d'ophtalmologie, Hôpital central, Nancy.
Becker
A
A
Berrod
J P
JP
Raspiller
A
A
D000913:Antibodies, Protozoan / Q000032:analysis; D002825:Chorioretinitis / Q000209:etiology* / Q000517:prevention & control / Q000628:therapy; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011446:Prospective Studies; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D014125:Toxoplasmosis, Congenital / Q000150:complications* / Q000276:immunology / Q000628:therapy
D000913:Antibodies, Protozoan
La choriorétinite toxoplasmique congénitale.