title: [Injections without needles in the treatment of insulin-dependent diabetes].
abstract: Jet injectors, which force a fluid under considerable pressure through a very small opening, have recently become available for subcutaneous administration of insulin. Use of the new devices introduced on the market is neither simpler nor more complicated than use of a syringe. Although jet injectors are highly attractive to both patients and parents, they can be used in only a limited range of diabetics. Main limitations to more widespread use include: 1) the small capacity of the devices which cannot inject more than 20 units of 40 unit/ml insulin; 2) modifications in the pharmacokinetic effects of insulins, especially long-acting insulins; 3) the high price of the injectors. Young children, who often find it difficult to accept injections, may be the main potential target for jet injector therapy. A trial period at home should always be scheduled before considering the purchase of a jet injector.
authors.affiliation: Unité d'Endocrinologie et Diabète de l'Enfant, Hôpital des Enfants Malades, Paris.
authors.forename: J J
authors.initials: JJ
authors.lastname: Robert
authors.forename: J
authors.initials: J
authors.lastname: Jos
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy*; D006801:Humans; D007277:Injections, Jet / Q000295:instrumentation*; D007328:Insulin / Q000008:administration & dosage*
chemical_list: D007328:Insulin
vernacular_title: Les injecteurs sans aiguille dans le traitement du diabète insulinodépendant.