title: Fibromuscular dysplasia complicated by primary thrombocythemia presenting recurrent ischemic cerebrovascular accidents: a case report.
abstract: A patient with fibromuscular dysplasia associated with primary thrombocythemia is reported. The patient, a 46-year-old female, had recurrent episodes of ischemic cerebrovascular accidents. Cranial CT scans revealed multiple low density areas in the right frontal and parietal lobes, and cerebral angiograms showed evidence of multiple embolisms. In addition, occlusion of the right internal carotid artery developed. To our knowledge, this is the first report on fibromuscular dysplasia complicated by essential thrombocythemia. The pathogenesis of the severe thrombotic tendency is discussed.
authors.affiliation: Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Abe
authors.forename: S
authors.initials: S
authors.lastname: Ohta
authors.forename: T
authors.initials: T
authors.lastname: Komiya
authors.forename: N
authors.initials: N
authors.lastname: Sakamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Mizuno
mesh_terms: D015901:Angiography, Digital Subtraction; D001241:Aspirin / Q000627:therapeutic use; D002340:Carotid Artery Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D002533:Cerebral Angiography; D002539:Cerebral Arterial Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D004359:Drug Therapy, Combination; D005260:Female; D005352:Fibromuscular Dysplasia / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000209:etiology; D002546:Ischemic Attack, Transient / Q000000981:diagnostic imaging / Q000209:etiology*; D008875:Middle Aged; D012008:Recurrence; D013920:Thrombocythemia, Essential / Q000150:complications* / Q000188:drug therapy; D013988:Ticlopidine / Q000627:therapeutic use
chemical_list: D013988:Ticlopidine; D001241:Aspirin