title: Mechanisms for pyrrolizidine alkaloid activation and detoxification.
authors.affiliation: Toxicology Program, Oregon State University, Corvallis 97331.
authors.forename: D R
authors.initials: DR
authors.lastname: Buhler
authors.forename: C L
authors.initials: CL
authors.lastname: Miranda
authors.forename: B
authors.initials: B
authors.lastname: Kedzierski
authors.forename: R L
authors.initials: RL
authors.lastname: Reed
mesh_terms: D000818:Animals; D001711:Biotransformation; D005978:Glutathione / Q000378:metabolism; D066298:In Vitro Techniques; D008658:Inactivation, Metabolic; D008297:Male; D008862:Microsomes, Liver / Q000378:metabolism; D016686:Monocrotaline / Q000031:analogs & derivatives*; D011763:Pyrrolizidine Alkaloids / Q000378:metabolism / Q000493:pharmacokinetics* / Q000633:toxicity; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D011763:Pyrrolizidine Alkaloids; C056840:senecionine N-oxide; D016686:Monocrotaline; C009237:senecionine; D005978:Glutathione; C007241:dehydroretronecine