Prospects for an HIV-vaccine.
A vaccine against HIV is badly needed. In the average clinical situation the virus displays a low-rate capacity to transfer infection. The frequency is significantly below 1 per contact situation, that is, a single infectious unit is the normal cause of infection. The time to induce disease in the adult is between 5 and 10 years. These facts are considered positive in relation to producing an HIV vaccine to achieve sterilizing and/or protective immunity. A summary of animal and human HIV/SIV vaccine studies is made giving certain support for the prospects of producing an HIV vaccine.
Wigzell
H
H
Department of Immunology, Karolinska Institute, Stockholm, Sweden.
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology / Q000517:prevention & control*; D000818:Animals; D006678:HIV / Q000276:immunology*; D006801:Humans; D014765:Viral Vaccines / Q000494:pharmacology / Q000633:toxicity
D014765:Viral Vaccines