title: [New aspects of drug hepatotoxicity].
abstract: This article sets out to report the new hepatotoxic drugs identified during the course of 1989 and to describe the state of the art about drugs suspected of hepatotoxicity, such as amoxicillin-a clavulinic or, to a lesser extent, octreotide. In contrast, Exifone, a recently introduced drug, was withdrawn from the market within a year. One is surprised to find drugs such as Buprenorphine and Trimebutine listed, which have never induced clinical cases of hepatitis despite widespread use. The article also reviews the drugs with recognized hepatotoxicity and tries to present the most up-to-date information about them.
authors.affiliation: Service d'Hépatologie et de Gastroentérologie, Saint-Brieuc.
authors.forename: P
authors.initials: P
authors.lastname: Denjean
authors.forename: O
authors.initials: O
authors.lastname: Nouel
authors.forename: J M
authors.initials: JM
authors.lastname: N'Guyen
authors.forename: C
authors.initials: C
authors.lastname: Beneton
authors.forename: H
authors.initials: H
authors.lastname: Allain
mesh_terms: D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans
vernacular_title: Nouveautés en hépatotoxicité médicamenteuse.