title: [Tonsillitis associated with Chlamydia trachomatis and antimicrobial therapy with rokitamycin].
abstract: Tonsillitis is the most common disease in the otorhinolaryngeal location. For most patients, tonsillitis is attributed to a group A streptococcal infection if the throat culture is positive for that organism or to a viral infection if the throat culture is negative. However, recent studies have shown that Chlamydia trachomatis can produce tonsillar infection. In this study, we evaluated the efficacy of Rokitamycin, a 16-membered ring macrolide antibiotic agent, in the treatment of tonsillitis associated with C. trachomatis. In 26 of 28 (92.9%) patients from whom C. trachomatis was isolated, the organism was eradicated by antimicrobial treatment with Rokitamycin of five days to three weeks' duration. In 25 of the 26 patients, they were totally free of tonsillar symptoms.
authors.affiliation: Division of Otorhinolayngology, Kitasato Institute Hospital.
authors.forename: H
authors.initials: H
authors.lastname: Ogawa
authors.forename: K
authors.initials: K
authors.lastname: Hashiguchi
authors.forename: Y
authors.initials: Y
authors.lastname: Kazuyama
mesh_terms: D000328:Adult; D000368:Aged; D002648:Child; D002690:Chlamydia Infections; D002692:Chlamydia trachomatis; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015644:Miocamycin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D014069:Tonsillitis / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D015644:Miocamycin; C033383:rokitamycin