[Measurement of the erythrocyte galactokinase activity in patients with presenile and senile idiopathic cataract. Preliminary study].
The activity of galactokinase in red blood cells, has been assayed in 17 patients with idiopathic senile and presenile cataract and in 12 age-matched subjects with perfectly transparent lenses. 3 of the idiopathic cataract patients (17.6%) showed low erythrocytes GK activity, while nobody in the control group showed reduced GK activity. Although preliminary, our results seem to support the possibility that a chronic disorder of galactose metabolism may be involved in the pathogenesis of the idiopathic senile and presenile cataract.
Simonelli
F
F
Cattedra di Oftalmologia Pediatrica, I Facoltà di Medicina e Chirurgia dell'Università di Napoli.
Frunzio
S
S
Rinaldi
M
M
Balestrieri
P
P
Giovane
A
A
Cotticelli
L
L
Rinaldi
E
E
D000328:Adult; D000367:Age Factors; D000368:Aged; D002386:Cataract / Q000145:classification / Q000201:enzymology*; D004912:Erythrocytes / Q000201:enzymology*; D005686:Galactokinase / Q000097:blood* / Q000172:deficiency; D005690:Galactose / Q000378:metabolism; D006801:Humans; D008875:Middle Aged
D005686:Galactokinase; D005690:Galactose
Valutazione dell'attività galattochinasica eritrocitaria in pazienti con cataratta idiopatica presenile e senile. Studio preliminare.