Structure and synthesis of an immunoactive lipopeptide, WS1279, of microbial origin.
The structure of WS1279, isolated from Streptomyces sp. as an immunoactive lipopeptide, has been deduced on the basis of chemical and physical evidence as S-[2,3-bis(palmitoyloxy)propyl]-N alpha-palmitoyl-Cys-Asn-Ser-Gly-Gly-Ser- OH. This was confirmed by synthesis.
Tsuda
Y
Y
Faculty of Pharmaceutical Sciences, Kobe-Gakuin University, Japan.
Okada
Y
Y
Tanaka
M
M
Shigematsu
N
N
Hori
Y
Y
Goto
T
T
Hashimoto
M
M
D000595:Amino Acid Sequence; D008074:Lipoproteins / Q000138:chemical synthesis / Q000737:chemistry*; D008969:Molecular Sequence Data; D013302:Streptomyces / Q000032:analysis
D008074:Lipoproteins; C065847:WS 1279