title: [Prognostic significance of syncope in patients with Wolff-Parkinson-White syndrome].
abstract: The prognostic value of syncope in symptomatic patients with Wolff-Parkinson-White syndrome (WPW) is unknown. Therefore, in order to evaluate the sensibility, specificity, positive and negative predictive value of syncope and compare those values with the one obtained for the shortest RR interval (less than or equal to 250 msec) as well as for the anterograde refractory period of the accessory pathway (less than 270 msec), we reviewed the clinical and electrophysiological data of 158 symptomatic patients with WPW. Fourty-eight patients (30%) reported at least one episode of syncope, and 24 out of 158 patients experienced an aborted sudden death, probably due to rapid conduction via the accessory pathway during atrial fibrillation. Syncope has poor sensibility but high specificity in recognizing an aborted sudden death. However, the syncope demonstrated it had a lower prognostic value when compared with other electrophysiological parameters in correctly identifying patients with a history of ventricular tachycardia and/or fibrillation. In conclusion, the data of this study propose the symptom "syncope" as a frequent event in the history of symptomatic patients with WPW referred to electrophysiological study. Generally its presence does not correctly identify patients who experienced an aborted sudden death. Furthermore, its prognostic value is significantly lower than a shorter RR interval (less than or equal to 250 msec) during atrial fibrillation and an anterograde effective refractory period less than 270 msec.
authors.affiliation: Dipartimento di Cardiologia, Facoltà di Medicina, Hannover, Germania.
authors.forename: A
authors.initials: A
authors.lastname: Auricchio
authors.forename: H
authors.initials: H
authors.lastname: Klein
authors.forename: H J
authors.initials: HJ
authors.lastname: Trappe
authors.forename: J
authors.initials: J
authors.lastname: Troester
mesh_terms: D000328:Adult; D001281:Atrial Fibrillation / Q000209:etiology; D003645:Death, Sudden / Q000209:etiology; D015150:Echocardiography, Doppler; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D013575:Syncope / Q000175:diagnosis / Q000209:etiology*; D014927:Wolff-Parkinson-White Syndrome / Q000150:complications / Q000175:diagnosis*
vernacular_title: Significato prognostico della sincope in pazienti con sindrome di Wolff-Parkinson-White.