Immunologic investigations in eight patients with incontinentia pigmenti.
We studied eight patients with incontinentia pigmenti to investigate the possibility of immunologic abnormalities. In six patients a defect of polymorphonuclear chemotaxis was revealed; lymphocyte subpopulations, serum immunoglobulin levels, and peripheral eosinophils were within normal limits. We hope these findings will stimulate further investigations into the mechanisms involved.
Menni
S
S
Institute of Dermatologic Clinic 1st, University of Milan, Italy.
Piccinno
R
R
Biolchini
A
A
Plebani
A
A
D000293:Adolescent; D002634:Chemotaxis, Leukocyte; D002648:Child; D002675:Child, Preschool; D005260:Female; D006098:Granulocytes; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007184:Incontinentia Pigmenti / Q000276:immunology* / Q000473:pathology; D016131:Lymphocyte Subsets; D008297:Male
D007136:Immunoglobulins