title: [Cytogenetic study of the mutagenicity of cucumarioside].
abstract: Mutagenic activity of cucumarioside displaying strong immunomodulating effect was studied. Two cytogenetic tests--mouse bone marrow micronucleus assay and the method for analysis of chromosomal aberrations--were used to evaluate mutagenic activity. Both tests demonstrated negative mutagenic effect.
authors.forename: S I
authors.initials: SI
authors.lastname: Polikarpova
authors.forename: O N
authors.initials: ON
authors.lastname: Volkova
authors.forename: A M
authors.initials: AM
authors.lastname: Sedov
authors.forename: V A
authors.initials: VA
authors.lastname: Stonik
authors.forename: V G
authors.initials: VG
authors.lastname: Likhoded
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000187:drug effects; D002869:Chromosome Aberrations; D006027:Glycosides; D006697:Holothurin / Q000235:genetics*; D051379:Mice; D015162:Micronucleus Tests; D009153:Mutagens; D012616:Sea Cucumbers; D014315:Triterpenes / Q000494:pharmacology*
chemical_list: D006027:Glycosides; D009153:Mutagens; D014315:Triterpenes; D006697:Holothurin; C033504:cucumarioside
vernacular_title: Tsitogeneticheskoe izuchenie mutagennosti kukumariozida.