[Use of xydiphone diphosphonate for correcting the course of posttraumatic bone regeneration in protracted hypodynamia].
Experiments were conducted on rats to study the effect of daily injection of xydiphone diphosphonate in a dose of 5 mg/100 g on bone tissue in normal motor activity and in hypodynamia caused by amputation of a limb and posttraumatic regeneration. It was established that xydiphone inhibits thinning of the diaphyseal cortical layer induced by hypodynamia and normalizes the parameters which characterize posttraumatic bone tissue regeneration in an unsupported position of the limb.
Alekseeva
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D000818:Animals; D001861:Bone Regeneration / Q000187:drug effects*; D004164:Diphosphonates / Q000627:therapeutic use*; D012968:Etidronic Acid; D005260:Female; D007103:Immobilization / Q000009:adverse effects*; D008297:Male; D051381:Rats; D013997:Time Factors; D014945:Wound Healing / Q000187:drug effects*
D004164:Diphosphonates; D012968:Etidronic Acid
Primenenie difosfonata ksidifona dlia korrektsii techeniia posttravmaticheskoĭ regeneratsii kostnoĭ tkani pri dlitel'noĭ gipodinamii.