Inhibitory effect of cis-dehydromatricaria ester isolated from Solidago altissima on the growth of mammalian cells.
A cell growth inhibitory substance was isolated from Solidago altissima, which is known as a naturalized weed. The data of infrared spectrum, proton and carbon-13 nuclear magnetic resonance spectrum, and mass spectrum were identical with those of cis-dehydromatricaria ester. The compound inhibited both tumor and normal mammalian cells.
Matsunaga
H
H
Hospital Pharmacy, Saga Medical School, Japan.
Katano
M
M
Tasaki
M
M
Yamamoto
H
H
Mori
M
M
Takata
K
K
D000480:Alkynes / Q000302:isolation & purification / Q000494:pharmacology*; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D005231:Fatty Acids, Unsaturated / Q000302:isolation & purification / Q000494:pharmacology*; D006801:Humans; D051379:Mice; D010946:Plants, Medicinal / Q000032:analysis*; D053279:Polyynes; D014407:Tumor Cells, Cultured / Q000187:drug effects* / Q000473:pathology
D000480:Alkynes; D000972:Antineoplastic Agents, Phytogenic; D005231:Fatty Acids, Unsaturated; D053279:Polyynes; C044104:dehydromatricaria methyl ester