title: Metabolic control theory: the geometry of the triangle.
abstract: The definitions of flux control coefficients and elasticity coefficients as given in the Metabolic Control Theory are introduced by geometrical considerations. It is shown that a method to determine the (non-normalized) control coefficients from the elasticity coefficients as well as the well-known summation and connectivity relationships can easily be derived in a geometric way. This method is explained in the light of a simple example, but it can be applied to any metabolic system. A software implementation (program "control") and possible applications to biotechnology are briefly presented.
authors.affiliation: IBCN-CNRS 1, Bordeaux, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Mazat
authors.forename: T
authors.initials: T
authors.lastname: Letellier
authors.forename: C
authors.initials: C
authors.lastname: Reder
mesh_terms: D001709:Biotechnology; D001711:Biotransformation; D003198:Computer Simulation; D004548:Elasticity; D008433:Mathematics; D008660:Metabolism; D008954:Models, Biological