title: Animal ventilator controlled by central respiratory phases.
abstract: An animal ventilator based on the principle of constant gas flow is described. The ventilator can operate either in a fixed cycle mode or in cycle-triggered mode. In the first case the built-in generator allows the setting of respiration rate and of the ratio of inspiratory duration to total respiratory cycle duration. When operated in cycle-triggered mode, phrenic nerve activity by means of an external respiratory phase detector controls the action of the pump. An internal circuitry allows precise no-inflation maneuvers. The device provides logical timing signals suitable for cycle-triggered averaging of respiration-related neuronal activity. The ventilator has proven its usefulness in experiments on reflex control of central respiration in paralyzed rabbits.
authors.affiliation: Department of Physiology and Pathophysiology, University of Mainz, F.R.G.
authors.forename: K
authors.initials: K
authors.lastname: Schmid
mesh_terms: D000818:Animals; D000830:Animals, Laboratory; D001921:Brain / Q000502:physiology*; D004559:Electric Wiring; D004867:Equipment Design; D012119:Respiration / Q000502:physiology*; D012121:Respiration, Artificial / Q000295:instrumentation*