Retinal and choroidal vaso-occlusive disease in systemic lupus erythematosus associated with antiphospholipid antibodies.
Three patients with systemic lupus erythematosus (SLE) associated with anti-phospholipid antibodies are reported. All three had severe vaso-occlusive disease: the first had an unilateral vaso-occlusive retinopathy, the second an unilateral central retinal venous obstruction, and the third a bilateral ischemic choroidopathy. The association of these occlusive ocular vascular diseases with the presence of the lupus anticoagulant and other associated factors in SLE is discussed.
Snyers
B
B
Department of Ophthalmology, Saint-Luc University Hospital, University of Louvain Medical School, Brussels, Belgium.
Lambert
M
M
Hardy
J P
JP
D000293:Adolescent; D000328:Adult; D001157:Arterial Occlusive Diseases / Q000276:immunology*; D001323:Autoantibodies / Q000276:immunology*; D002308:Cardiolipins / Q000276:immunology*; D002829:Choroid / Q000098:blood supply*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D008297:Male; D010743:Phospholipids / Q000276:immunology*; D012170:Retinal Vein Occlusion / Q000276:immunology; D012171:Retinal Vessels
D001323:Autoantibodies; D002308:Cardiolipins; D010743:Phospholipids