Effect of Trypanosoma vivax infection on energy and nitrogen metabolism of west African dwarf goats.
A study was conducted using 32 mature 22-kg West African Dwarf Goats to measure the effect of Trypanosoma vivax infection on energy and nitrogen metabolism. Sixteen goats were infected intravenously with 14 X 10(6) T. vivax. Sixteen control goats were sham-injected. Digestibility and metabolizability of energy and N balance were measured for each goat. Heat production and energy balances were measured per treatment group from 1 wk before infection to 6 wk after infection. Goats were fed alfalfa pellets (10% above maintenance). Treated goats had a reduced (P less than .05) packed cell volume (38 to 40% before infection vs 20 to 25% 6 wk after infection) and an increased (P less than .05) rectal temperature. Log parasitemia/ml was about 6.0 to 6.2. Parasitized goats showed increased urine creatinine excretion at wk 2 postinfection. After infection, feed intake was reduced (about 15%; P less than .05) and greater variability in intake was noted. Treated and control goats had similar N output and energy output in urine. Metabolizability of energy intake was similar at 42.7 vs 42.1% in treated vs control goats, respectively. Heat production in infected goats was increased by about 15%. Treated goats lost more weight and had a lower N balance than control goats (P less than .05). The calculated maintenance energy requirement for infected goats (464 kJ ME/kg.75) was 25% greater than for control goats (375 kJ ME/kg.75).
Verstegen
M W
MW
Dept. of Anim. Nutr., Agricultural University, Wageningen, The Netherlands.
Zwart
D
D
van der Hel
W
W
Brouwer
B O
BO
Wensing
T
T
D000818:Animals; D001835:Body Weight; D003404:Creatinine / Q000652:urine; D004063:Digestion; D004435:Eating; D004734:Energy Metabolism; D015511:Goat Diseases / Q000378:metabolism* / Q000473:pathology; D006041:Goats; D006400:Hematocrit / Q000662:veterinary; D008297:Male; D009584:Nitrogen / Q000378:metabolism*; D014352:Trypanosomiasis / Q000378:metabolism / Q000473:pathology / Q000662:veterinary*; D014508:Urea / Q000097:blood / Q000652:urine
D014508:Urea; D003404:Creatinine; D009584:Nitrogen