Role of the acetone inducible P-450IIE1 in the deethylation of diethylnitrosamine in hamster.
Gervasi
P G
PG
Istituto di Mutagenesi e Differenziamento, CNR, Pisa, Italy.
Puccini
P
P
Longo
V
V
Lippi
A
A
D000096:Acetone / Q000494:pharmacology; D000818:Animals; D006224:Cricetinae; D019392:Cytochrome P-450 CYP2E1; D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis / Q000378:metabolism*; D004052:Diethylnitrosamine / Q000378:metabolism*; D004790:Enzyme Induction / Q000187:drug effects; D066298:In Vitro Techniques; D007700:Kinetics; D008297:Male; D008647:Mesocricetus; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism; D010088:Oxidoreductases / Q000378:metabolism; D010089:Oxidoreductases, N-Demethylating / Q000096:biosynthesis / Q000378:metabolism*
D000096:Acetone; D004052:Diethylnitrosamine; D003577:Cytochrome P-450 Enzyme System; D010088:Oxidoreductases; C029225:diethylnitrosamine deethylase; D019392:Cytochrome P-450 CYP2E1; D010089:Oxidoreductases, N-Demethylating