Acute meningoradiculitis concomitant with seroconversion to human immunodeficiency virus type 1.
We report a case of acute regressive meningoradiculitis concomitant with HIV1 primoinfection. The clinical symptoms were mild and disappeared spontaneously. Electromyographic studies confirmed the regressive demyelinating-type process. The biological diagnosis of HIV1 infection was demonstrated by viral antigen detection, by the presence of the integrated proviral DNA after gene amplification by a polymerase chain reaction, and in particular, by the steady progression in the appearance of different HIV1-specific antibodies. This was shown using three different Western blot kits whose performances were compared.
Paton
P
P
Hôpital de l'Hôtel-Dieu, Service de Médecine Interne, Lyon, France.
Poly
H
H
Gonnaud
P M
PM
Tardy
J C
JC
Fontana
J
J
Kindbeiter
K
K
Tête
R
R
Madjar
J J
JJ
D000208:Acute Disease; D000328:Adult; D015153:Blotting, Western; D004576:Electromyography; D005260:Female; D006679:HIV Seropositivity / Q000150:complications* / Q000175:diagnosis; D015497:HIV-1; D006801:Humans; D008581:Meningitis / Q000150:complications* / Q000175:diagnosis; D016133:Polymerase Chain Reaction; D011843:Radiculopathy / Q000150:complications* / Q000175:diagnosis; D011933:Reagent Kits, Diagnostic
D011933:Reagent Kits, Diagnostic