Disulfiram inhibits the in vitro growth of methicillin-resistant staphylococcus aureus.
Several antibiotics have disulfiram-like effects; we evaluated disulfiram for its antibiotic-like effects. Disulfiram inhibited the in vitro growth of methicillin-resistant Staphylococcus aureus, with an MIC of 1.33 micrograms/ml, but was not effective against members of the family Enterobacteriaceae or Pseudomonas species.
Phillips
M
M
Department of Medicine, St. Vincent's Medical Center of Richmond, Staten Island, New York 10310.
Malloy
G
G
Nedunchezian
D
D
Lukrec
A
A
Howard
R G
RG
D004221:Disulfiram / Q000494:pharmacology*; D004755:Enterobacteriaceae / Q000187:drug effects; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D011549:Pseudomonas / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000254:growth & development
D004221:Disulfiram