title: [Functional evaluation of gastric and jejunal transplant after esophagectomy].
abstract: Increased survival rates after esophagectomy for cancer and the significant development of forms of therapy alternate to surgical treatment, today compel surgeons to devote far more attention to the methods will pursue in reconstructing the alimentary tract after removal of the esophagus. Nine patients with esophago-gastro-plasty and 6 with esophago-jejuno-plasty, after esophagectomy for cancer, experienced a study of esophageal function. The study consisted of extended esophago-gastro-intestinal manometry, performed both while at digestive rest after a semi-solid meal, and of scintigraphy, performed to investigate gastric emptying. 24-hours esophago-gastric pH-metry was also executed, along with basal and stimulated acidity metering in, patients with gastroplasty. The fundamental alterations, from the manometric point of view in esophago-gastro-plasty, are the absence of phase III of the IMMC interdigestively and in the absence of a motor response when ingesting the meal. Scintigraphically this coincides with a fundamental alteration of gastric tubule emptying. On the contrary, in jejunoplasty the jejunal loop retains adequate motility, both during the interdigestive phase and following a meal. Such strikingly diverse motor behavior explains the higher quality of life of patients with jejunoplasty versus patients in whom the stomach is used to substitute for the esophagus.
authors.affiliation: Istituto di Clinica Chirurgica Generale e Terapia Chirurgica, Università degli Studi di Genova.
authors.forename: N
authors.initials: N
authors.lastname: Pandolfo
authors.forename: L
authors.initials: L
authors.lastname: Spigno
authors.forename: G
authors.initials: G
authors.lastname: Guiddo
authors.forename: G
authors.initials: G
authors.lastname: Tronfi
authors.forename: G
authors.initials: G
authors.lastname: Villavecchia
authors.forename: F P
authors.initials: FP
authors.lastname: Mattioli
mesh_terms: D003679:Deglutition; D004938:Esophageal Neoplasms / Q000601:surgery*; D005746:Gastric Emptying; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007583:Jejunum / Q000503:physiopathology* / Q000637:transplantation*; D008365:Manometry; D013270:Stomach / Q000503:physiopathology* / Q000637:transplantation*
vernacular_title: Valutazione funzionale dell'impianto gastrico e digiunale dopo esofagectomia.