title: Hemobilia due to vasculitis of the gall bladder in a patient with mixed connective tissue disease.
abstract: A 30-year-old woman with mixed connective tissue disease presented with acute abdominal pain and signs of blood loss. At cholecystectomy she appeared to have lost a considerable amount of blood into the biliary tract due to bleeding of the gall bladder. Microscopic examination showed vasculitis of the gall bladder wall. Hemobilia has not been described before as a complication in mixed connective tissue disease.
authors.affiliation: Department of Internal Medicine, University Hospital Groningen, The Netherlands.
authors.forename: E J
authors.initials: EJ
authors.lastname: Kuipers
authors.forename: M A
authors.initials: MA
authors.lastname: van Leeuwen
authors.forename: P G
authors.initials: PG
authors.lastname: Nikkels
authors.forename: J
authors.initials: J
authors.lastname: Jager
authors.forename: M H
authors.initials: MH
authors.lastname: van Rijswijk
mesh_terms: D000208:Acute Disease; D000328:Adult; D003520:Cyclophosphamide / Q000627:therapeutic use; D005260:Female; D005704:Gallbladder / Q000098:blood supply*; D005705:Gallbladder Diseases / Q000209:etiology; D006431:Hemobilia / Q000209:etiology*; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D008947:Mixed Connective Tissue Disease / Q000150:complications* / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use; D014657:Vasculitis / Q000150:complications* / Q000209:etiology
chemical_list: D003520:Cyclophosphamide; D011239:Prednisolone