title: [Various mechanisms of circulatory failure in septic shock].
abstract: The main parameters of hemodynamic and myocardial contractile activity, transcapillary fluid and proteins exchange have been studied in healthy and infected anaesthetized dogs with source of purulent infection during septic shock development. Besides, blood gas tension, pH and toxicity of blood and lymph are determined as well. It is shown that damage of microcirculation promoting tissue hypoxia and endogenous intoxication, is responsible for the initiation of decompensating disturbance of circulation at pus process generalization.
authors.forename: A S
authors.initials: AS
authors.lastname: Khromov
authors.forename: V F
authors.initials: VF
authors.lastname: Sagach
authors.forename: A V
authors.initials: AV
authors.lastname: Dmitrieva
authors.forename: L B
authors.initials: LB
authors.lastname: Doloman
mesh_terms: D000818:Animals; D001424:Bacterial Infections / Q000150:complications*; D001427:Bacterial Toxins / Q000008:administration & dosage*; D004195:Disease Models, Animal; D004285:Dogs; D005243:Feces / Q000382:microbiology; D005260:Female; D006333:Heart Failure / Q000209:etiology*; D006439:Hemodynamics / Q000502:physiology; D008297:Male; D009200:Myocardial Contraction / Q000502:physiology; D012772:Shock, Septic / Q000150:complications / Q000503:physiopathology*; D014946:Wound Infection / Q000150:complications*
chemical_list: D001427:Bacterial Toxins
vernacular_title: Nekotorye mekhanizmy nedostatochnosti krovoobrashcheniia pri septicheskom shoke.