Electromyographic guidance of botulinum toxin treatment in cervical dystonia.
We report the results of electromyographic (EMG) guidance in the treatment of cervical dystonia with botulinum toxin. Eight-four patients received a total of 225 injection sessions. Overall there was moderate objective improvement in 78.7%. The mean dose of toxin was 269 +/- 39 mouse lethal units and the mean duration of maximum effect was 107 +/- 49 days. Complications included excessive neck weakness in 16.0% and dysphagia in 11.1% of the injection sessions. We conclude that EMG guidance is a safe and effective method of administering botulinum toxin in the treatment of cervical dystonia.
Dubinsky
R M
RM
Department of Neurology, University of Kansas Medical Center, Kansas City 66103.
Gray
C S
CS
Vetere-Overfield
B
B
Koller
W C
WC
D000328:Adult; D000368:Aged; D001905:Botulinum Toxins / Q000627:therapeutic use*; D002574:Cervical Vertebrae; D004421:Dystonia / Q000188:drug therapy* / Q000503:physiopathology; D004576:Electromyography; D006801:Humans; D008875:Middle Aged; D014103:Torticollis / Q000188:drug therapy / Q000503:physiopathology
D001905:Botulinum Toxins