Ethopharmacology: a creative approach to identification and characterisation of novel psychotropics.
The present contribution describes the basic fundamentals of animal models in ethopharmacology. After defining the role of ethopharmacology in the development of animal models of relevant human diseases, this methodology is used to classify different categories of aggression. Furthermore, the behavioural aspects of agonistic (aggressive) modelling are outlined and the various models used to describe offensive and defensive behaviours, and some miscellaneous models are summarized. Finally, some remarks on the new class of psychoactive drugs, serenics, are given.
Olivier
B
B
Department of Pharmacology, Duphar B.V., Weesp, The Netherlands.
Rasmussen
D
D
Raghoebar
M
M
Mos
J
J
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D004353:Drug Evaluation, Preclinical / Q000379:methods; D011619:Psychotropic Drugs / Q000494:pharmacology*
D011619:Psychotropic Drugs