[Investigation of a transfusion contaminated by HTLV-I virus].
In front of the successive development of an HTLV-I seroconversion and a neuromyelopathy in a French Caucasian following a cardiac transplantation, an ascendant epidemiologic investigation must be manage to search a risk factor or a possible blood donor contaminated with HTLV-I virus. We selected an HTLV-I seropositive donor whose RBC participated to the patient's transfusion. This woman from Martinique island was a regular donor in our blood center and a second investigation was initiated to examine the patients transfused with the blood products issued from her previous donation. Nine were identified and controlled among them a patient who has received a RBC was found HTLV-I seropositive. An evaluation of the infectivity of the different blood products according to their type and specificity has been done. These data confirm that transmission of the HTLV-I is possible through donation of healthy seropositive donor and can induce the development of associated pathology, and prove the importance of screening blood donors for HTLV-I antibodies.
Fretz
C
C
CTS Pitié-Salpêtrière, Paris.
Jaulmes
D
D
Nicod
A
A
Jourdan
G
G
Gout
O
O
Gessain
A
A
Jullien
A M
AM
Gluckman
J C
JC
de Thé
G
G
Fournel
J J
JJ
D000328:Adult; D001782:Blood Donors; D017707:Erythrocyte Transfusion; D015490:HTLV-I Infections / Q000635:transmission*; D016027:Heart Transplantation; D006801:Humans; D017713:Platelet Transfusion; D012307:Risk Factors; D065227:Transfusion Reaction
Enquête à propos d'une contamination transfusionnelle par le virus HTLV-I.