Inhibiting action human glioblastoma extract on haemolytic complement of human and xenogeneic sera.
The action of some extracts of human glioblastoma of the haemolytic complement of human and xenogeneic sera has been examined. The study suggests that the antigenic products of some human glioblastomas may induce an inhibiting effect on the haemolytic complement of human, as well as xenogeneic (rat and rabbit), sera. The inhibiting action on the xenogeneic sera is indicative of the presence of species-specific antigens or tumor cells, comparable to that of normal tissues.
Occhiogrosso
M
M
Chair of Neurosurgery, University of Bari, Italy.
De Tommasi
A
A
Vailati
G
G
D000818:Animals; D001790:Blood Physiological Phenomena; D001932:Brain Neoplasms / Q000378:metabolism*; D015941:Complement Hemolytic Activity Assay; D003165:Complement System Proteins / Q000502:physiology*; D005910:Glioma / Q000378:metabolism*; D006461:Hemolysis; D006801:Humans; D051381:Rats / Q000097:blood; D011919:Rats, Inbred Strains; D014020:Tissue Extracts / Q000494:pharmacology*
D014020:Tissue Extracts; D003165:Complement System Proteins