Bilateral stromal Leydig cell tumour of the ovary. Case report and literature review.
The stromal Leydig cell tumour of the ovary is a very rare benign neoplasm which usually occurs in postmenopausal women. Due to a significant production of androgens by the tumour, it is frequently associated with symptoms of virilization. To our knowledge only 7 cases have been reported in the literature, one of them with bilateral manifestation. We report an additional case affecting both ovaries in a 59-year-old nun with long-standing virilism, review the literature, and discuss the histomorphological features for differential diagnosis.
Böhm
J
J
Institute of Pathology, Technical University of Munich, School of Medicine, FRG.
Röder-Weber
M
M
Höfler
H
H
Kolben
M
M
D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007984:Leydig Cell Tumor / Q000175:diagnosis / Q000473:pathology*; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000473:pathology*