title: [Leiomyosarcoma of the prostate. Report of a case].
abstract: Sarcomas of the prostate are rare tumors and are predominantly rhabdomyosarcoma in children and leiomyosarcoma in the young adult (less than 50 years). We report on a rare case of prostate sarcoma in a 49-year-old patient whose presenting features were those of rapidly evolving prostatism and dyschezia (rectal constipation). The diagnosis was established histopathologically by cytology and biopsy. Despite the initial chemotherapeutic treatment, the course of the disease was fulminant and the patient died from multiple lymphatic metastases. We discuss its embryonal origin, clinical features, differential diagnosis and underscore the need for sequential combined treatment with chemotherapy, surgery and post-operative radiotherapy.
authors.affiliation: Servicio de Urología del Hospital de Alicante-SVS, Unidad Docente Facultad de Medicina de Alicante, Universidad de Alicante, España.
authors.forename: P
authors.initials: P
authors.lastname: Romero Pérez
authors.forename: J J
authors.initials: JJ
authors.lastname: Lobato Encinas
authors.forename: J
authors.initials: J
authors.lastname: Megías Garrigos
authors.forename: A
authors.initials: A
authors.lastname: Mira Llinares
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003609:Dactinomycin / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D007890:Leiomyosarcoma / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000145:classification / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology*; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D003609:Dactinomycin; D014750:Vincristine; D004317:Doxorubicin
vernacular_title: Leiomiosarcoma de próstata. Aportación de un caso.