[Experimental study of the pathological mechanism of thromboxane A2 in alkaline ocular burn].
The authors investigated the pathological mechanism of thromboxane A2 in alkaline burn of the eye. Thromboxane B2 (metabolic product of thromboxane A2) in aqueous humor of the burned eye significantly increased in 30 minutes after the burn. The pathological change was the formation of thrombosis 2 hours after the alkaline burn, especially in the anterior segment. The role of thromboxane A2 in alkaline burn of the eye was ascertained.
Song
L Y
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Department of Ophthalmology, Second Teaching Hospital, Harbin Medical University.
D000468:Alkalies; D000818:Animals; D000869:Anterior Eye Segment / Q000378:metabolism; D001082:Aqueous Humor / Q000378:metabolism; D002057:Burns, Chemical; D005126:Eye Burns / Q000139:chemically induced* / Q000378:metabolism; D008297:Male; D011817:Rabbits; D013927:Thrombosis / Q000209:etiology; D013928:Thromboxane A2 / Q000502:physiology; D013929:Thromboxane B2 / Q000378:metabolism*
D000468:Alkalies; D013929:Thromboxane B2; D013928:Thromboxane A2