[The characteristics of the lecithin-cholesterol-acyltransferase reaction in the blood serum during liver regeneration].
The rate of cholesterin ether formation in blood serum during the periods of rapid recovery of liver mass decreases after partial hepatectomy in rats. This effect is connected with the changes in quantity and composition of lecithin cholesterin acyltransferase (LCAT) as well the kinetic characteristics of lipoprotein of high density. This ferment was isolated from blood serum and purified in 28,500 times at different periods of liver regeneration. A conclusion concerning the presence of reverse dependence between the pronounced regeneration processes in liver and LCAT activity at high level of nonetherificated cholesterin in substrate has been drawn. Some recommendations for LCAT activity reducing processes in liver are given.
Chirkin
A A
AA
Konevalova
N Iu
NIu
Gidranovich
L G
LG
D000818:Animals; D002784:Cholesterol / Q000097:blood; D002788:Cholesterol Esters / Q000097:blood; D006498:Hepatectomy; D008115:Liver Regeneration / Q000502:physiology*; D008297:Male; D007862:Phosphatidylcholine-Sterol O-Acyltransferase / Q000097:blood*; D010743:Phospholipids / Q000097:blood; D051381:Rats; D013997:Time Factors
D002788:Cholesterol Esters; D010743:Phospholipids; D002784:Cholesterol; D007862:Phosphatidylcholine-Sterol O-Acyltransferase
Kharakteristika letsitin-kholesterol-atsiltransferaznoĭ reaktsii v syvorotke krovi pri regeneratsii pecheni.