[Treatment of toxoplasmosis. The treatment of toxoplasmic chorioretinitis].
Toxoplasmosis is the commonest cause of inflammatory disease of the posterior segment of the eye. We treated 23 patients with acute toxoplasma chorioretinitis with sulfonamides, pyrimethamine and corticosteroids for a period of 4 weeks. All patients with acute disease had characteristic foci and a positive titer on the Sabin-Feldman dye test. In all patients, we observed clinical improvement within 2 weeks, but one patient with a lesion larger than 2 disc diameters improved after the third week. During the follow-up period ranging from 6 months to 6 years (mean 2.5 years), there have been four recurrences (17%). No serious side effects of treatment were observed in our patients.
Psilas
K
K
Université d'Ionnina, Grèce.
Petroutsos
G
G
Aspiotis
M
M
D000293:Adolescent; D000328:Adult; D002648:Child; D002825:Chorioretinitis / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011241:Prednisone / Q000627:therapeutic use*; D011739:Pyrimethamine / Q000627:therapeutic use*; D012008:Recurrence; D013449:Sulfonamides / Q000627:therapeutic use*; D014126:Toxoplasmosis, Ocular / Q000188:drug therapy*
D013449:Sulfonamides; D011241:Prednisone; D011739:Pyrimethamine
Traitement de la toxoplasmose. Le traitement de la chorio-rétinite toxoplasmique.