Laser-Doppler flowmetry in the assessment of "mild" Raynaud's phenomenon and its treatment.
Raynaud's phenomenon is characterised by a reduction in skin temperature and blood flow. Laser-Doppler Flowmetry (LDF) has been used to evaluate LDF recovery time after immersion of hands in water at 20 degrees C for 1 minute before and after treatment. After treatment for 4 weeks with nifedipine 10 mg b.i.d. the recovery time was again measured. The study showed that the treatment is useful for normalising the recovery times and reducing symptoms.
Cesarone
M R
MR
Irvine Cardiovascular Laboratory, St. Mary's Hospital, London, UK.
Laurora
G
G
Smith
S R
SR
Belcaro
G
G
D000328:Adult; D005069:Evaluation Studies as Topic; D005385:Fingers / Q000098:blood supply*; D006801:Humans; D007834:Lasers; D009543:Nifedipine / Q000627:therapeutic use; D011928:Raynaud Disease / Q000188:drug therapy*; D012039:Regional Blood Flow / Q000187:drug effects
D009543:Nifedipine