[Presence of HBsAg in lymphocyte cultured from patients infected with human immunodeficiency virus (HIV)].
The behavior of the hepatitis B virus was investigated in mononuclear cell cultures in nine patients infected by the human immunodeficiency virus. Although only one of them was a carrier of HBsAg and four had anti-HBs in their sera, HBsAg was detected in the supernatant of the cultures from all patients. These results suggest that mononuclear cells might act as a reservoir for hepatitis B virus, and that the concomitant infection by this virus and human immunodeficiency virus may alter the natural evolution of any of both conditions.
Cisterna
R
R
Departamento de Microbiología e Immunología, Hospital Civil de Bilbao, Universidad del País Vasco.
Sarría
L
L
Suñen
E
E
Campelo
C
C
Martínez
J
J
Fernández de Aránguiz
A
A
Gorriño
T
T
Malavé
C
C
D000328:Adult; D002353:Carrier State / Q000175:diagnosis; D002478:Cells, Cultured; D003470:Culture Media / Q000032:analysis; D005188:False Negative Reactions; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006509:Hepatitis B / Q000150:complications / Q000175:diagnosis*; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006515:Hepatitis B virus / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000276:immunology* / Q000382:microbiology; D008297:Male; D009693:Nucleic Acid Hybridization; D015819:Substance Abuse, Intravenous / Q000150:complications
D003470:Culture Media; D006514:Hepatitis B Surface Antigens
Presencia de HBsAg en cultivos de linfocitos de pacientes infectados por el virus de la inmunodeficiencia humana (VIH).