title: Synergism between clindamycin and colloidal bismuth subcitrate against Helicobacter (Campylobacter) pylori in vitro.
abstract: A combination of clindamycin and colloidal bismuth subcitrate was evaluated for synergistic inhibition of Helicobacter pylori employing the agar dilution method. A total of 47 clinical isolates of Helicobacter pylori were examined. Synergistic interaction was observed in 36%, additive behaviour in 64% of the strains. No antagonism could be detected.
authors.affiliation: Institut für Medizinische Mikrobiologie und Infektionsimmunologie der Freien Universität, Berlin.
authors.forename: K
authors.initials: K
authors.lastname: Vogt
authors.forename: H
authors.initials: H
authors.lastname: Hahn
mesh_terms: D000897:Anti-Ulcer Agents / Q000494:pharmacology*; D002981:Clindamycin / Q000494:pharmacology*; D004357:Drug Synergism; D016480:Helicobacter pylori / Q000187:drug effects*; D006801:Humans; D008826:Microbial Sensitivity Tests; D009942:Organometallic Compounds / Q000494:pharmacology*
chemical_list: D000897:Anti-Ulcer Agents; D009942:Organometallic Compounds; D002981:Clindamycin; C002791:bismuth tripotassium dicitrate