[Adsorption mechanism of hexokinase activity regulation in rat sarcoma M-1].
The hexokinase interaction with mitochondrial membranes in rat sarcoma M-1 cells was studied. The conditions of formation of the enzyme complex with mitochondrial membranes and its stability were elaborated. The kinetic parameters of free and membrane-bound hexokinases were determined. The data obtained are discussed within the frame-work of the adsorption mechanism of hexokinase activity regulation in neoplastic tissues.
Garkusha
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Goncharova
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D000327:Adsorption; D000818:Animals; D004795:Enzyme Stability / Q000502:physiology; D006593:Hexokinase / Q000378:metabolism*; D007700:Kinetics; D008931:Mitochondria, Muscle / Q000201:enzymology; D051381:Rats; D012513:Sarcoma, Experimental / Q000201:enzymology*; D014407:Tumor Cells, Cultured
D006593:Hexokinase
Ob adsorbtsionnom mekhanizme reguliatsii aktivnosti geksokinazy v sarkome M-1 krys.