title: [Factors associated with generalized forms of arteriosclerosis in patients with coronary disease].
abstract: We studied the lipidic metabolism and the atherogenic risk factors non related to lipidic metabolism in two groups of patients: group 1 with only coronary disease and group 2 with coronary disease and atherosclerosis in the cerebral and/or peripheric artery territories. Patients of group 2 showed a cholesterol, cLDL, and B-apoprotein titers significantly higher than group 1. Systolic and diastolic blood pressure were higher in group two. Also the incidence of diabetes mellitus in group 2 was higher than in group 1. In a stepwise discriminating analysis the diastolic arterial pressure and cholesterol titers were the parameters with a greatest predictive potential for the presence of localized or generalized ischemic disease. B-apoprotein was the lipidic parameter with the greatest predictive potential. All together these data suggest that in coronary patients, a discrete increase in plasma cholesterol can imply a risk of suffering ischemia in some other arterial territories. Diastolic blood pressure, cholesterol and diabetes mellitus are the factors with the highest predictive potential for the generalization of arteriosclerosis.
authors.affiliation: Servicio de Medicina Interna, Hospital de Bellvitge Princeps d'Espanya, Barcelona.
authors.forename: X
authors.initials: X
authors.lastname: Pintó
authors.forename: E
authors.initials: E
authors.lastname: Llargués
authors.forename: C
authors.initials: C
authors.lastname: Fiol
authors.forename: C
authors.initials: C
authors.lastname: Marcos
authors.forename: F
authors.initials: F
authors.lastname: Fernández-Nogués
authors.forename: R
authors.initials: R
authors.lastname: Pujol
mesh_terms: D001161:Arteriosclerosis / Q000097:blood / Q000453:epidemiology*; D002545:Brain Ischemia / Q000097:blood / Q000453:epidemiology; D003327:Coronary Disease / Q000097:blood / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007511:Ischemia / Q000097:blood / Q000453:epidemiology; D007866:Leg / Q000098:blood supply; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology
chemical_list: D008055:Lipids
vernacular_title: Factores asociados a formas generalizadas de arteriosclerosis en pacientes con enfermedad coronaria.