title: Polymorphisms of the regulators of complement activation gene cluster.
abstract: The regulators of complement activation (RCA) constitute a tightly linked gene family that controls the activity of the complement system. Genetic polymorphisms have been reported for all of RCA genes at the DNA, RNA and/or protein levels. In addition, multiple RNA and/or protein products have been observed for most of these genes. These polymorphisms and variants are instrumental in the study of the structure, evolution and function of the RCA family.
authors.affiliation: Howard Hughes Medical Institute Laboratories, Department of Medicine, Washington University, St. Louis, Mo.
authors.forename: D
authors.initials: D
authors.lastname: Hourcade
authors.forename: T W
authors.initials: TW
authors.lastname: Post
authors.forename: V M
authors.initials: VM
authors.lastname: Holers
authors.forename: D M
authors.initials: DM
authors.lastname: Lublin
authors.forename: J P
authors.initials: JP
authors.lastname: Atkinson
mesh_terms: D000595:Amino Acid Sequence; D005075:Biological Evolution; D003167:Complement Activation / Q000235:genetics*; D005809:Genes, Regulator; D008040:Genetic Linkage; D014644:Genetic Variation; D006801:Humans; D008969:Molecular Sequence Data; D005810:Multigene Family; D011110:Polymorphism, Genetic