Intestinal schwannoma in a rhesus monkey.
An intestinal schwannoma (neurilemmoma) was found in an aged female rhesus monkey culled from a research colony. The neoplasm was characterized principally by palisades of spindle-shaped cells (Antoni type A) surrounded by thick argyrophilic fibres, while plump cells with areas of vacuolation (Antoni type B) were observed to a lesser extent. Thick hyalinized perivascular cuffs were prominent and multifocal thromboses were present in cavernous vascular channels. Electron microscopic examination of the intercellular matrix between Antoni type A cells revealed long-spacing (100 to 120 nm) collagen fibrils. Although the mass had expanded beyond the confines of the muscularis externa, the cytological features of the neoplasm appeared benign.
Barbolt
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Toxicology Department, Sterling Research Group, Rensselaer, NY 12144.
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D000818:Animals; D005260:Female; D007414:Intestinal Neoplasms / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary*; D008253:Macaca mulatta; D008854:Microscopy, Electron; D008992:Monkey Diseases / Q000473:pathology*; D009442:Neurilemmoma / Q000473:pathology / Q000648:ultrastructure / Q000662:veterinary*