Food intake and meal patterns in rhesus monkeys: significance of chronic hyperinsulinemia.
To investigate the role of plasma insulin on food intake, we have examined the effect of naturally occurring chronic hyperinsulinemia on the feeding behavior of male rhesus monkeys. Two groups of monkeys, a group with normal fasting insulin concentrations (52.4 +/- 2.2 microU/ml) (mean +/- SE) and a hyperinsulinemic group (148.6 +/- 14.5 microU/ml), were selected to be similar in weight, 13.0 +/- 1.0 and 15.3 +/- 0.5 kg, respectively, prior to study. Food intake and feeding patterns were recorded and analyzed. No differences in either daily caloric intake, 815.2 +/- 27.4 versus 890.0 +/- 64.2 kcal (p less than 0.32), or feeding patterns were found. The number of meals taken per day did not differ between the two groups, 8.7 +/- 1.7 versus 6.7 +/- 1.1 (p less than 0.35), nor did meal size differ, 129 +/- 16.5 versus 110.5 +/- 16.3 (p less than 0.45). We conclude that chronic endogenous hyperinsulinemia as it occurs naturally in some obese rhesus monkeys has no significant effect on daily feeding behavior.
Hannah
J
J
Department of Physiology, School of Medicine, University of Maryland, Baltimore.
Hansen
B C
BC
D000818:Animals; D004435:Eating / Q000502:physiology*; D002149:Energy Intake / Q000502:physiology; D005502:Food; D006946:Hyperinsulinism / Q000503:physiopathology*; D007328:Insulin / Q000097:blood; D007457:Iodine Radioisotopes; D008253:Macaca mulatta; D008297:Male; D009765:Obesity / Q000503:physiopathology
D007328:Insulin; D007457:Iodine Radioisotopes