Chronic haemodialysis with bicarbonate dialysate. Technical and clinical aspects.
Bicarbonate as a physiological buffer should be preferred in haemodialysis treatments. The use of bicarbonate dialysis, however, varies from 30 to 100% in the different industrialised countries. Except for the many advantages using bicarbonate dialysate, there are also clinical pitfalls in the use of the bicarbonate buffer substrate. Furthermore, technical problems can be expected in the use of varying dialysate bicarbonate concentrations, as in the concomitant use of acetate and bicarbonate dialysate in the same dialysis unit. This paper deals with the clinical and technical aspects of bicarbonate dialysis.
Leunissen
K M
KM
Department of Nephrology, University Hospital Maastricht, The Netherlands.
Claessens
P J
PJ
Mooy
J M
JM
van Hooff
J P
JP
Shaldon
S
S
D000085:Acetates; D000137:Acid-Base Imbalance / Q000139:chemically induced; D001419:Bacteria / Q000302:isolation & purification; D001639:Bicarbonates / Q000009:adverse effects; D004731:Endotoxins / Q000032:analysis; D015312:Hemodialysis Solutions / Q000009:adverse effects; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D000860:Hypoxia / Q000139:chemically induced; D006435:Renal Dialysis / Q000009:adverse effects / Q000379:methods*; D013242:Sterilization
D000085:Acetates; D001639:Bicarbonates; D004731:Endotoxins; D015312:Hemodialysis Solutions