title: The gene encoding human protective protein (PPGB) is on chromosome 20.
abstract: Normal lymphocyte prometaphase chromosome spreads were hybridized in situ using single- and double-color fluorescence techniques. The results obtained with either the 1.8-kb protective protein cDNA or a 12-kb genomic fragment of the human protective protein gene as probe demonstrate that the PPGB gene is localized on the long arm of chromosome 20. This assignment was confirmed by hybridization with whole chromosome DNA libraries.
authors.affiliation: Department of Cytochemistry and Cytometry, University of Leiden, The Netherlands.
authors.forename: J
authors.initials: J
authors.lastname: Wiegant
authors.forename: N J
authors.initials: NJ
authors.lastname: Galjart
authors.forename: A K
authors.initials: AK
authors.lastname: Raap
authors.forename: A
authors.initials: A
authors.lastname: d'Azzo
mesh_terms: D002268:Carboxypeptidases / Q000235:genetics*; D043402:Cathepsin A; D002478:Cells, Cultured; D002874:Chromosome Mapping; D002890:Chromosomes, Human, Pair 20; D005455:Fluorescent Antibody Technique; D006023:Glycoproteins / Q000235:genetics*; D006801:Humans; D008297:Male; D009693:Nucleic Acid Hybridization
chemical_list: D006023:Glycoproteins; D002268:Carboxypeptidases; C468629:CTSA protein, human; D043402:Cathepsin A