title: [The effect of melatonin and epiphysectomy on the function of the mono-oxygenase system in rat liver].
abstract: After chronic melatonin administration (1 mg/kg, 14 days) the content of cytochrome P-450 and activity of NADPH: cytochrome c-reductase in rat microsomes were increased. Pinealectomized rats had opposite directed shifts in microsomal oxidation. In these animals activated effect of melatonin was absent.
authors.forename: A V
authors.initials: AV
authors.lastname: Popov
authors.forename: V V
authors.initials: VV
authors.lastname: Zarubin
authors.forename: E B
authors.initials: EB
authors.lastname: Arushanian
authors.forename: T M
authors.initials: TM
authors.lastname: Luneva
mesh_terms: D000818:Animals; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D008862:Microsomes, Liver / Q000187:drug effects* / Q000201:enzymology; D010084:Oxidation-Reduction / Q000187:drug effects; D010105:Oxygenases / Q000187:drug effects* / Q000378:metabolism; D010870:Pineal Gland / Q000502:physiology* / Q000601:surgery; D051381:Rats
chemical_list: D010105:Oxygenases; D008550:Melatonin
vernacular_title: Vliianie melatonina i épifizéktomii na sostoianie monooksigenaznoĭ sistemy pecheni krys.