title: Quinones and their glutathione conjugates as irreversible inhibitors of glutathione S-transferases.
authors.affiliation: TNO-CIVO Toxicology and Nutrition Institute, Department of Biological Toxicology, Zeist, The Netherlands.
authors.forename: B
authors.initials: B
authors.lastname: van Ommen
authors.forename: J J
authors.initials: JJ
authors.lastname: Bogaards
authors.forename: J P
authors.initials: JP
authors.lastname: Ploemen
authors.forename: J
authors.initials: J
authors.lastname: van der Greef
authors.forename: P J
authors.initials: PJ
authors.lastname: van Bladeren
mesh_terms: D000818:Animals; D016227:Benzoquinones / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D002703:Chloranil / Q000031:analogs & derivatives / Q000378:metabolism / Q000494:pharmacology; D005978:Glutathione / Q000031:analogs & derivatives / Q000378:metabolism / Q000494:pharmacology*; D005982:Glutathione Transferase / Q000037:antagonists & inhibitors*; D006801:Humans; D066298:In Vitro Techniques; D007527:Isoenzymes / Q000037:antagonists & inhibitors; D007700:Kinetics; D051381:Rats; D013329:Structure-Activity Relationship
chemical_list: D016227:Benzoquinones; D007527:Isoenzymes; D002703:Chloranil; C057105:2-gluthionyl-3,5,6-trichloro-1,4-benzoquinone; D005982:Glutathione Transferase; D005978:Glutathione