Drug-induced fever: a clinical report and challenge test with calcium dobesilate.
A 54-year-old man was receiving calcium dobesilate for retinopathy and after 8 days he presented fever of more than 39 degrees C, generalized myalgia, chills and headache. Other causes of fever were ruled out. A challenge test was done with a single therapeutic oral dose of calcium dobesilate and fever appeared 20 h later and lasted 8 h. Our patient fulfils Young's stringent criteria for drug fever. To our knowledge drug-induced fever due to calcium dobesilate has not been reported previously.
Puyana
J
J
Department of Allergy, Ramon y Cajal Hospital, Madrid, Spain.
Fraj
J
J
De La Hoz
F
F
Davila
I
I
Vergara
C
C
Cuesta
J
J
D002123:Calcium Dobesilate / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology*; D005334:Fever / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged
D002123:Calcium Dobesilate