title: [Ulcer disease of endocrine origin associated with a non-gastrin substance].
abstract: The purpose of this paper is to report on a form of duodenal ulceration associated with a major hypersecretion that we described in 1984. This entity belongs to the group of endocrine duodenal ulcer diatheses of which the Zollinger-Ellison Syndrome (ZES) in the prototype. We have recently in 1989 reported a series of patients with clinical and pathologic features indistinguishable from those of the Zollinger-Ellison syndrome but without hypergastrinemia. We have also found that the plasma and the tumor tissues of these patients contains a potent non-gastrin secretagogue.
authors.affiliation: Service de Chirurgie générale, Université de Rochester, New York.
authors.forename: R
authors.initials: R
authors.lastname: Menguy
authors.forename: W W
authors.initials: WW
authors.lastname: Chey
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005744:Gastric Acid / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000150:complications*; D010437:Peptic Ulcer / Q000209:etiology*
vernacular_title: Maladie ulcéreuse d'origine endocrine véhiculée par une substance non-gastrinique.