title: [Disseminated annular granuloma in a patient with scabies].
abstract: A male patient of 52 years old is studied with an scabiei by Sarcoptes scabiei v. hominis. After a month the patient developed a clinic and histopathologic generalized granuloma annulare. With the specific local treatment of his scabiei, the disease was cured in 7 days. After this treatment, the generalized granuloma annulare disappeared within 2 months. Due to the sequence of both diseases and the way in which they disappeared after local therapy, we suggest that the antigens of the scabies are the ones responsible for the granulomatous lesions. We concluded this since once the antigens have disappeared, the immunologic mechanisms depending on the interactions of lymphocyte T-macrophage which form the granuloma are interrupted. Since the patient is homosexual, we studied the HIV antibodies which were negatives in several opportunities. Nevertheless, an immune disbalance which could be the coadjuvant factor was founded. With this case we show that specific exogens may cause a generalized granuloma annulare.
authors.affiliation: Servicio de Dermatología, Hospital Maciel, Montevideo, Uruguay.
authors.forename: R A
authors.initials: RA
authors.lastname: Vignale
authors.forename: E
authors.initials: E
authors.lastname: Casella de Vilaboa
authors.forename: J
authors.initials: J
authors.lastname: Paciel
authors.forename: J
authors.initials: J
authors.lastname: Bruno
mesh_terms: D006099:Granuloma / Q000276:immunology* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012532:Scabies / Q000150:complications*; D012871:Skin Diseases / Q000276:immunology* / Q000473:pathology
vernacular_title: Granuloma anular diseminado en un paciente con escabiosis.