title: Corticosteroid- and furosemide-induced increase in proteinuria in nephrosis.
abstract: A corticosteroid- and furosemide-induced excessive increase in proteinuria developed in a 34-year-old nephrotic patient with focal glomerulosclerosis. The concentration of urinary protein increased almost in parallel with that of urinary glucose. This finding indicates that corticosteroids and/or furosemide can promote the disturbance of the tubular reabsorption mechanism together with increases in glomerular permeability and glomerular filtration rate.
authors.affiliation: First Department of Internal Medicine, Osaka City University Medical School, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Inoue
authors.forename: M
authors.initials: M
authors.lastname: Okamura
authors.forename: N
authors.initials: N
authors.lastname: Negoro
authors.forename: M
authors.initials: M
authors.lastname: Fujisawa
authors.forename: H
authors.initials: H
authors.lastname: Inariba
authors.forename: T
authors.initials: T
authors.lastname: Takeda
authors.forename: Y
authors.initials: Y
authors.lastname: Kanayama
mesh_terms: D000328:Adult; D005665:Furosemide / Q000009:adverse effects*; D005923:Glomerulosclerosis, Focal Segmental / Q000150:complications*; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000009:adverse effects*; D009401:Nephrosis / Q000150:complications*; D011507:Proteinuria / Q000139:chemically induced* / Q000209:etiology
chemical_list: D005665:Furosemide; D008775:Methylprednisolone