Juxtaglomerular cell tumor of the kidney. Morphological, immunohistochemical and ultrastructural studies of a new case.
The authors describe a Juxtaglomerular Cell Tumor (JGCT) in a hypertensive young man whose symptomatology disappeared when the JGCT was removed. The clinical diagnosis was made before surgery by selective determination of plasma renin activity level in both renal veins and in the draining vein of the tumor. This neoplasm is benign and usually occurs in young patients. The morphological, immunocytochemical and ultrastructural features are described. Other renin-secreting tumors and the theories about histogenesis of JGCT are discussed.
López G-Asenjo
J A
JA
Department of Pathology, Hospital Universitario San Carlos, Madrid, Spain.
Blanco González
J
J
Ortega Medina
L
L
Sanz Esponera
J
J
D000328:Adult; D006801:Humans; D007150:Immunohistochemistry; D007606:Juxtaglomerular Apparatus / Q000737:chemistry / Q000473:pathology* / Q000648:ultrastructure; D007680:Kidney Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron