title: [In vivo activation of the kallikrein-kinin system of rats by human Hageman factor fragments].
abstract: Administration of factor XIIf prepared from human plasma activated the kallikrein-kinin system in vivo. In rats there was a decrease in kallikreinogen as well as a short decrease of the mean arterial blood pressure. The results described are of importance for the research of pathogenesis of shock.
authors.affiliation: Institut für Pathologische Biochemie, Medizinischen Hochschule Carl Gustav Carus Dresden.
authors.forename: M
authors.initials: M
authors.lastname: Taucher
authors.forename: K
authors.initials: K
authors.lastname: Herzmann
authors.forename: H
authors.initials: H
authors.lastname: Kühne
authors.forename: D W
authors.initials: DW
authors.lastname: Scheuch
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D005174:Factor XII / Q000494:pharmacology*; D006801:Humans; D016234:Kallikrein-Kinin System / Q000187:drug effects*; D008297:Male; D010446:Peptide Fragments / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D012769:Shock / Q000209:etiology*
chemical_list: D010446:Peptide Fragments; D005174:Factor XII
vernacular_title: In-vivo-Aktivierung des Kallikrein-Kinin-Systems der Ratte mit humanem Hageman-Faktor-Fragment.