title: [Results of the treatment of infertility by the method of extracorporeal fertilization].
abstract: Outpatient in vitro insemination has been performed in 609 infertile couples in 1145 menstrual cycles. Age of the women ranged from 19 to 44 years and their history of infertility, from 2 to 17 years. Tubal infertility was present in 439 patients and one or both tubes were patent in 170 patients. Superovulation was induced with anti-estrogens and gonadotropins (Humegon and Neopergonal). Preovulatory oocytes were retrieved using transvaginal follicular puncture guided by transvaginal ovarian ultrasonography. A total of 942 punctures yielded 2177 oocytes (2.3 per puncture). The incidence of conception was 63.3% of the entire population and 75.2% of the mature oocyte population. Division was documented in 1176 zygotes (85.2%). Embryo transfers were undertaken in 498 cycles (2.4 embryos per transfer). There were 80 conceptions (16.1% of transfers); 19 (23.7%) of them were "biochemical" and 10 (12.5%) ended in spontaneous abortion; pregnancy was ectopic in 5 (6.3%) patients. As of March 1, 1990, 46 (57.5%) women gave birth to 51 normal infants (5 twins). The therapeutic results are consistent with experience of world clinics.
authors.forename: V M
authors.initials: VM
authors.lastname: Zdanovskiĭ
authors.forename: I M
authors.initials: IM
authors.lastname: Griaznova
authors.forename: M B
authors.initials: MB
authors.lastname: Anshina
authors.forename: K N
authors.initials: KN
authors.lastname: Kechnian
authors.forename: E V
authors.initials: EV
authors.lastname: Solomatina
mesh_terms: D000328:Adult; D004624:Embryo Transfer / Q000379:methods*; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D007317:Insemination, Artificial, Homologous / Q000379:methods*; D008297:Male; D009865:Oocytes / Q000254:growth & development / Q000637:transplantation*
vernacular_title: Rezul'taty lecheniia besplodiia metodom ékstrakorporal'nogo oplodotvoreniia.