Hemoglobin associated acetaldehyde correlates with the Self-Administered Alcoholism Screening Test but not glycated hemoglobin in type II diabetes mellitus.
Twenty seven subjects with Type II diabetes mellitus underwent analysis of the Self-Administered Alcoholism Screening Test (SAAST) and hemoglobin associated acetaldehyde levels (HbAA). The SAAST scores and HbAA levels correlated with one another (r = .48, p = 0.009). No correlation between glycated hemoglobin levels (GHb) and HbAA levels or SAAST was found. Glucose incubation of whole blood led to an increase in GHb but no change in HbAA. We conclude that HbAA and SAAST correlate with each other when measured in patients with diabetes. Therefore each test appears clinically useful in quantifying alcohol consumption in individuals with Type II diabetes mellitus.
Peterson
C M
CM
Sansum Medical Research Foundation, Santa Barbara, CA 93105.
Scott
B K
BK
Jovanovic-Peterson
L
L
D000079:Acetaldehyde / Q000097:blood*; D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000097:blood*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D012646:Self Administration
D000079:Acetaldehyde; D006442:Glycated Hemoglobin; D006454:Hemoglobins