Epidermal growth factor enhances, and transforming growth factor-beta inhibits DNA synthesis with similar potency in hepatocytes from normal and from 24 h and 48 h regenerating rat liver.
Strain
A J
AJ
Liver Unit, Queen Elizabeth Hospital, University of Birmingham, Edgbaston, U.K.
D000818:Animals; D004247:DNA / Q000096:biosynthesis; D004815:Epidermal Growth Factor / Q000494:pharmacology*; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008115:Liver Regeneration / Q000187:drug effects / Q000502:physiology; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D016212:Transforming Growth Factor beta / Q000494:pharmacology*
D016212:Transforming Growth Factor beta; D004815:Epidermal Growth Factor; D004247:DNA