Ovarian ablation failures by radiation: a comparison of two dose schedules.
Sixty Chinese breast cancer patients underwent ovarian irradiation with one of two dose schedules: 12 Gy/4 fractions/4-6 days or 14 Gy/4 fractions/4-6 days. The ovarian ablation failure rates were 14% and 0% respectively in patients above 40 years of age. The overall ablation failure rate in younger patients was unacceptably high at 35%. The significance of the findings is discussed.
Leung
S F
SF
Department of Clinical Oncology, Prince of Wales Hospital, Hong Kong.
Tsao
S Y
SY
Teo
P M
PM
Choi
P H
PH
Shiu
W C
WC
D000328:Adult; D001943:Breast Neoplasms / Q000628:therapy*; D005260:Female; D006801:Humans; D008598:Menstruation / Q000528:radiation effects; D010053:Ovary / Q000528:radiation effects*; D011879:Radiotherapy Dosage; D012189:Retrospective Studies