title: The effectiveness of a preventive regimen on the periodontal health of patients undergoing chemotherapy for leukemia and lymphoma.
abstract: In patients with leukemia or lymphoma, the role of preventive oral hygiene in reducing infectious periodontal complications during aggressive chemotherapy is well documented. However, the effectiveness of these measures in preventing further dental or periodontal degradation remains to be demonstrated. 34 hospitalized patients with malignant heamatological diseases were observed. During chemotherapy, tooth brushing was replaced by 3 daily mouth-rinses with 0.2% chlorhexidine digluconate. The periodontal status of these patients, appears unchanged after 12 months. This suggests that the prophylactic measures do prevent a measurable periodontal degradation, even in the presence of pre-existing periodontal disease.
authors.affiliation: Department of Periodontology, School of Dental Medicine and Stomatology, Catholic University of Louvain, Belgium.
authors.forename: F
authors.initials: F
authors.lastname: De Beule
authors.forename: P
authors.initials: P
authors.lastname: Bercy
authors.forename: A
authors.initials: A
authors.lastname: Ferrant
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D000666:Amphotericin B / Q000627:therapeutic use; D002442:Ceftazidime / Q000627:therapeutic use; D002710:Chlorhexidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003774:Dental Plaque Index; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D007654:Ketoconazole / Q000627:therapeutic use; D007938:Leukemia / Q000188:drug therapy; D008223:Lymphoma / Q000188:drug therapy; D008825:Miconazole / Q000627:therapeutic use; D009643:Norfloxacin / Q000627:therapeutic use; D010510:Periodontal Diseases / Q000188:drug therapy*; D010512:Periodontal Index; D016388:Tooth Loss; D014640:Vancomycin / Q000627:therapeutic use
chemical_list: D014640:Vancomycin; D008825:Miconazole; D000666:Amphotericin B; D015725:Fluconazole; D002442:Ceftazidime; C010882:chlorhexidine gluconate; D009643:Norfloxacin; D002710:Chlorhexidine; D007654:Ketoconazole; D000212:Acyclovir