title: Dietary vitamins A, C, and E and selenium as risk factors for cervical cancer.
abstract: The relation between cervical cancer and dietary intake of vitamins A, C, and E, beta-carotene, and selenium was examined in a population-based case-control study in Utah. Cervical cancer cases (n = 266) and population-based controls (n = 408) were interviewed between 1984 and 1987. Protective effects were observed for vitamins A, C, and E and beta-carotene but were attenuated by age, level of education, and lifetime cigarette use. Associated risk (comparing highest with lowest quartiles of intake) went from 0.53 (crude) to 0.71 (adjusted) for vitamin A; from 0.55 (crude) to 0.82 (adjusted) for beta-carotene; from 0.45 (crude) to 0.55 (adjusted) for vitamin C; from 0.58 (crude) to 0.60 (adjusted) for vitamin E; and from 0.95 (crude) to 0.70 (adjusted) for selenium. Adjustment for number of sex partners and church attendance, factors significantly related to cervical cancer risk, only slightly attenuated these adjusted risk estimates.
authors.affiliation: Department of Family and Preventive Medicine, University of Utah School of Medicine, Salt Lake City 84132.
authors.forename: M L
authors.initials: ML
authors.lastname: Slattery
authors.forename: T M
authors.initials: TM
authors.lastname: Abbott
authors.forename: J C
authors.initials: JC
authors.lastname: Overall
authors.forename: L M
authors.initials: LM
authors.lastname: Robison
authors.forename: T K
authors.initials: TK
authors.lastname: French
authors.forename: C
authors.initials: C
authors.lastname: Jolles
authors.forename: J W
authors.initials: JW
authors.lastname: Gardner
authors.forename: D W
authors.initials: DW
authors.lastname: West
mesh_terms: D000328:Adult; D001206:Ascorbic Acid Deficiency / Q000150:complications / Q000453:epidemiology*; D016022:Case-Control Studies; D003677:Deficiency Diseases / Q000150:complications / Q000453:epidemiology*; D004034:Diet Surveys; D004522:Educational Status; D005260:Female; D006801:Humans; D008875:Middle Aged; D012067:Religion; D012307:Risk Factors; D012643:Selenium / Q000172:deficiency*; D012747:Sexual Partners; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology; D014589:Utah / Q000453:epidemiology; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology*; D014802:Vitamin A Deficiency / Q000150:complications / Q000453:epidemiology*; D014811:Vitamin E Deficiency / Q000150:complications / Q000453:epidemiology*
chemical_list: D012643:Selenium