Free radicals generated in ethanol metabolism may be responsible for tumor promoting effects of ethanol.
Mufti
S I
SI
Department of Pharmacology and Toxicology, University of Arizona Health Sciences Center, Tucson 85721.
D000818:Animals; D002273:Carcinogens / Q000378:metabolism / Q000633:toxicity*; D003043:Cocarcinogenesis; D004052:Diethylnitrosamine / Q000633:toxicity; D004128:Dimethylnitrosamine / Q000031:analogs & derivatives / Q000633:toxicity; D004938:Esophageal Neoplasms / Q000139:chemically induced; D000431:Ethanol / Q000378:metabolism / Q000633:toxicity*; D005609:Free Radicals; D005978:Glutathione / Q000378:metabolism; D008114:Liver Neoplasms, Experimental / Q000139:chemically induced; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D002273:Carcinogens; D005609:Free Radicals; D004052:Diethylnitrosamine; D000431:Ethanol; C014707:nitrosobenzylmethylamine; D005978:Glutathione; D004128:Dimethylnitrosamine