title: [Presence of HBsAg in lymphocyte cultured from patients infected with human immunodeficiency virus (HIV)].
abstract: The behavior of the hepatitis B virus was investigated in mononuclear cell cultures in nine patients infected by the human immunodeficiency virus. Although only one of them was a carrier of HBsAg and four had anti-HBs in their sera, HBsAg was detected in the supernatant of the cultures from all patients. These results suggest that mononuclear cells might act as a reservoir for hepatitis B virus, and that the concomitant infection by this virus and human immunodeficiency virus may alter the natural evolution of any of both conditions.
authors.affiliation: Departamento de Microbiología e Immunología, Hospital Civil de Bilbao, Universidad del País Vasco.
authors.forename: R
authors.initials: R
authors.lastname: Cisterna
authors.forename: L
authors.initials: L
authors.lastname: Sarría
authors.forename: E
authors.initials: E
authors.lastname: Suñen
authors.forename: C
authors.initials: C
authors.lastname: Campelo
authors.forename: J
authors.initials: J
authors.lastname: Martínez
authors.forename: A
authors.initials: A
authors.lastname: Fernández de Aránguiz
authors.forename: T
authors.initials: T
authors.lastname: Gorriño
authors.forename: C
authors.initials: C
authors.lastname: Malavé
mesh_terms: D000328:Adult; D002353:Carrier State / Q000175:diagnosis; D002478:Cells, Cultured; D003470:Culture Media / Q000032:analysis; D005188:False Negative Reactions; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006509:Hepatitis B / Q000150:complications / Q000175:diagnosis*; D006514:Hepatitis B Surface Antigens / Q000032:analysis*; D006515:Hepatitis B virus / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000276:immunology* / Q000382:microbiology; D008297:Male; D009693:Nucleic Acid Hybridization; D015819:Substance Abuse, Intravenous / Q000150:complications
chemical_list: D003470:Culture Media; D006514:Hepatitis B Surface Antigens
vernacular_title: Presencia de HBsAg en cultivos de linfocitos de pacientes infectados por el virus de la inmunodeficiencia humana (VIH).