[Effect of fluoroquinolones made in China in the treatment of acute bacillary dysentery. A report of 212 cases].
212 cases of acute bacillary dysentery were treated with enoxacin and norfloxacin, another 15 cases were treated by chujunsheng. The cure rate in enoxacin group was 99.1%, in norfloxacin group 98.04% and in chujunsheng group 63.64%. The isolated pathogens were tested for susceptibility with disk diffusion and MIC determination. The results showed that both enoxacin and norfloxacin are better than gentamycin, ampicillin, chloramphenicol and trimethoprim-sulfamethoxazole. Side effects of enoxacin group and norfloxacin were noted in are 2.7% and 3.0% of the patients respectively. This study suggests that enoxacin and norfloxacin are highly effective, quite convenient for use and have few adverse reactions. They are considered to be drugs of choice for the treatment of acute bacillary dysentery.
Wang
X F
XF
302nd Hospital of PLA, Beijing.
Jiang
S C
SC
Wei
Y L
YL
D000208:Acute Disease; D004405:Dysentery, Bacillary / Q000188:drug therapy*; D015365:Enoxacin / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008826:Microbial Sensitivity Tests; D009643:Norfloxacin / Q000009:adverse effects / Q000627:therapeutic use*; D012764:Shigella sonnei / Q000187:drug effects
D015365:Enoxacin; D009643:Norfloxacin