[Relationship between aging and renal function: a positron emission tomographic study].
Blood volume (V), blood flow (F) and glomerular filtration rate (GFR) per 100 g (100 ml) of kidney were calculated with C15O, H(2)15O and 68Ga-EDTA, to study age-related changes per unit tissue in 19 subjects using positron emission tomography. Age was negatively correlated with V, F and GFR. The aging-related decrease in V was less marked than those in F and GFR. Analysis by regression formula induced that F, GFR for subjects in their 70s are 76%, 46% and 55% for those in their 20s, respectively.
Yamashita
M
M
Kyoto Prefectural University of Medicine.
Inaba
T
T
Oda
Y
Y
Mizukawa
N
N
Nakagawa
S
S
Furuya
S
S
Ushijima
Y
Y
Nakahashi
H
H
D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D001810:Blood Volume / Q000502:physiology; D005260:Female; D005919:Glomerular Filtration Rate / Q000502:physiology; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011866:Radioisotope Renography; D012079:Renal Circulation / Q000502:physiology; D014055:Tomography, Emission-Computed