title: [Clinical criteria and evaluation of the pathology and progress of lympho-nodular toxoplasmosis].
abstract: We aimed at analysis of the clinical pattern and the course of lympho-nodular toxoplasmosis taking into account the intensity and duration of the illness. Ninety seven patients (69 adults and 28 children) with lympho-nodular toxoplasmosis were examined. Toxoplasmosis was diagnosed by indirect immunofluorescence; the titres of antibodies of IgG and IgM classes were also estimated. Depending on the duration of the illness three periods: early, regression of symptoms and protraction of symptoms were defined; depending on the intensity of signs and symptoms of toxoplasmosis three courses of the disease: acute, subacute and chronic were defined. The analysis showed that clinical picture of lympho-nodular toxoplasmosis was characterized by swelling of various peripheral lymph nodes as well as by general clinical symptoms (88.7% of cases) the intensity and duration of which, to a large extent, determined course of the illness. No correlation between clinical course and duration (early and regression period) of lympho-nodular toxoplasmosis and titres IFA-IgG (before therapy) was found. Pathomorphology of lymph nodes in patients with toxoplasmic lymphadenopathy is a valuable complementary examination which renders it possible to determine the period of the disease.
authors.affiliation: Klinika Chorób Pasozytniczych i Tropikalnych, Instytut Mikrobiologii i Chorób Zakaźnych AM, Poznań.
authors.forename: W
authors.initials: W
authors.lastname: Kociecka
authors.forename: B
authors.initials: B
authors.lastname: Mrozewicz
authors.forename: E
authors.initials: E
authors.lastname: Simon
authors.forename: M
authors.initials: M
authors.lastname: Pakuła
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D014123:Toxoplasmosis / Q000175:diagnosis* / Q000503:physiopathology
vernacular_title: Kryteria kliniczne i ocena obrazu oraz przebiegu toksoplazmozy wezłowej.