[Experimental studies on the absorption of aconitine in the upper digestive tract].
This paper presents the experimental results of the absorption of orally administered aconitine in the upper digestive tract of rats. Taking the atrioventricular block in EKG as the main parameter, we have found that aconitine could be absorbed by the esophagus and stomach of the rat. Furthermore, the ability of the esophagus to absorb aconitine is stronger than that of the stomach.
Li
J
J
Institute of Chinese Materia Medica, China Academy of Traditional, Chinese Medicine, Beijing.
Gao
X
X
D000042:Absorption; D000157:Aconitine / Q000493:pharmacokinetics* / Q000633:toxicity; D000284:Administration, Oral; D000818:Animals; D004562:Electrocardiography; D004947:Esophagus / Q000378:metabolism*; D005753:Gastric Mucosa / Q000378:metabolism*; D006327:Heart Block / Q000139:chemically induced; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D000157:Aconitine