title: [New triterpenoidal sapogenins from the roots of Glycyrrhiza yunnanensis].
abstract: Two new pentacyclic triterpenoidal sapogenins of oleanane type, namely glyyunnansapogenin A (I) and glyyunnansapogenin B (II), together with a known compound beta-sitosterol were isolated and characterized from the roots of Glycyrrhiza yunnanensis Cheng f. et L. K. Tai, family Leguminosae, collected in Yunnan Province, China. I was obtained as its methyl ester (Ia), mp 276-277 degrees C, which formed a diacetate (Ic), mp 244-245 degrees C. II, mp 287-289 degrees C, gave a triacetate (IIb), mp 286-287 degrees C and a monomethyl ester (IIa), mp 272-275 degrees C, which further formed a triacetate (IIc), mp 187-189 degrees C and a diacetate (IId), mp 243-245 degrees C after treatment with acetic anhydride and pyridine over night at room temperature. The structures of I and II were established by spectral analyses of IR, 1H NMR, 13CNMR, MS, CD and ORD. Glyyunnansapogenin A (I) was proved to be 3 beta, 24-dihydroxy-16-oxo-olean-12-en-29-oic acid and glyyunnansapogenin B (II) 3 beta, 21 alpha, 24-trihydroxy-olean-12-en-30-oic acid respectively.
authors.affiliation: School of Pharmaceutical Science, Beijing Medical University.
authors.forename: L
authors.initials: L
authors.lastname: Zeng
authors.forename: R Y
authors.initials: RY
authors.lastname: Zhang
authors.forename: P
authors.initials: P
authors.lastname: Wei
authors.forename: D
authors.initials: D
authors.lastname: Wang
authors.forename: C Y
authors.initials: CY
authors.lastname: Gao
authors.forename: Z C
authors.initials: ZC
authors.lastname: Lou
mesh_terms: D055598:Chemical Phenomena; D002621:Chemistry; D006035:Glycyrrhiza / Q000032:analysis*; D010946:Plants, Medicinal; D012502:Sapogenins / Q000302:isolation & purification*; D012855:Sitosterols / Q000302:isolation & purification; D014315:Triterpenes / Q000302:isolation & purification*
chemical_list: D012502:Sapogenins; D012855:Sitosterols; D014315:Triterpenes; C068182:glyyunnansapogenin A; C068183:glyyunnansapogenin B; C025473:gamma-sitosterol