title: [Evaluation of the efficacy of continuous epidural block with low concentration of local anesthetics in patients with ureterolithiasis].
abstract: Forty patients with ureterolithiasis were studied to evaluate the efficacy of a continuous epidural block with local anesthetics. The patients were randomly allocated into 3 groups: first group (n = 7) received continuous epidural administration of 1% mepivacaine at a rate of 2 ml.hr-1; second group (n = 19) received intermittent bolus administration of the same anesthetic 4-5 times daily; and third group (control group, n = 14) was treated by conventional therapy including infusion of Ringer's solution and diuretics. Among 3 groups, a comparison of the rate of abortion of ureter stone, the rate of mobilization of stone, and the frequency of operation was performed. The rate of abortion in group 1 was significantly higher than those of group 2 and control. The rate of mobilization of stone in group 1 tended to be higher than group 2 and control. Also the frequency of operation in group 1 tended to be lower than group 2. Effect of continuous administration with 1% mepivacaine in patient with ureterolithiasis was comparable to that of intermittent bolus administration of 2% mepivacaine or 0.5% bupivacaine reported. We conclude that the continuous block with 1% mepivacaine is effective and safe for treating the patient with ureterolithiasis.
authors.affiliation: Department of Anesthesiology, Akita University School of Medicine.
authors.forename: S
authors.initials: S
authors.lastname: Shigeomi
authors.forename: H
authors.initials: H
authors.lastname: Mitsuhata
authors.forename: S
authors.initials: S
authors.lastname: Matsumoto
authors.forename: M
authors.initials: M
authors.lastname: Yabe
authors.forename: K
authors.initials: K
authors.lastname: Ohtaka
mesh_terms: D000328:Adult; D000368:Aged; D000767:Anesthesia, Epidural; D005260:Female; D006801:Humans; D008096:Lithotripsy; D008297:Male; D008619:Mepivacaine; D008875:Middle Aged; D013997:Time Factors; D014514:Ureteral Calculi / Q000628:therapy*
chemical_list: D008619:Mepivacaine