[False positive serological tests for Borrelia burgdorferi in patients with primary antiphospholipid syndrome].
Serological tests for Borrelia burgdorferi were carried out in a series of 27 patients with primary antiphospholipid syndrome (PAPLS). The results showed a 14% prevalence of false positive Lyme disease serology in this patient population. In patients with PAPLS and false positive serologic tests for Borrelia burgdorferi neurological involvement was significantly more common (p = 0.012, Fisher's exact test) than in patients with PAPLS without that finding. We insist on the possibility that patients with PAPLS may have false positive serological tests for Borrelia burgdorferi as measured by IFI with the resulting diagnostic error. In these cases, confirmation by other techniques such as ELISA or immunoblotting is recommended.
Selva O'Callaghan
A
A
Servicio de Medicina Interna, Hospital General Vall d'Hebron, Barcelona.
Ordi Ros
J
J
Porcel Pérez
J M
JM
Tolosa Vilella
C
C
Jordana Comajuncosa
R
R
Juste Sánchez
C
C
Vilardell Tarrés
M
M
D000328:Adult; D000906:Antibodies / Q000032:analysis*; D000907:Antibodies, Bacterial / Q000032:analysis*; D015748:Borrelia burgdorferi Group / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005189:False Positive Reactions; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D015151:Immunoblotting; D007136:Immunoglobulins / Q000032:analysis; D008193:Lyme Disease / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D010743:Phospholipids / Q000276:immunology*; D013577:Syndrome
D000906:Antibodies; D000907:Antibodies, Bacterial; D007136:Immunoglobulins; D010743:Phospholipids
Serología falsamente positiva frente a Borrelia burgdorferi en pacientes con síndrome antifosfolípido primario.