title: [Synthesis and biological activity of 2-dialkylaminoalkoxybenzylidene-benzo-(b)-cyclanones].
abstract: The synthesis and the study of the cardiovascular and antiallergic properties of 2-(4-dialkylaminoalkoxybenzylidene)-benzo-[b]-1-cyclanones analogues to benzarone and amiodarone were performed. They showed the influence of the length of the basic dialkylaminoalkoxy group and that of a methoxy substitutant of the tetralone on the studied activities.
authors.affiliation: Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie de Paris-Sud, Châtenay-Malabry.
authors.forename: P G
authors.initials: PG
authors.lastname: Koutsourakis
authors.forename: S
authors.initials: S
authors.lastname: Kirkiacharian
mesh_terms: D000818:Animals; D001572:Benzofurans / Q000138:chemical synthesis* / Q000494:pharmacology; D001578:Benzopyrans / Q000138:chemical synthesis* / Q000494:pharmacology; D001597:Benzylidene Compounds / Q000138:chemical synthesis* / Q000494:pharmacology; D002317:Cardiovascular Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats; D011918:Rats, Inbred SHR
chemical_list: D001572:Benzofurans; D001578:Benzopyrans; D001597:Benzylidene Compounds; D002317:Cardiovascular Agents
vernacular_title: Synthèse et activité biologique de 2-dialkylaminoalkoxybenzylidène benzo-[b]-cyclanones.