title: The use of fibrinogen uptake test in screening for deep vein thrombosis in patients with hip fracture.
abstract: 255 hip fracture patients were studied by 125I-fibrinogen uptake test and bilateral phlebography. We found the sensitivity of fibrinogen scanning to be 44% for the non-operated limb and 50% for the calves. The predictive value of a negative result was found to be 92% and 93% respectively. We conclude that the use of fibrinogen uptake test as single diagnosticum is not valid and can only be recommended in combination with phlebography when studying patient where the frequency of DVT is expected to be low.
authors.affiliation: Department of Orthopedic Surgery, Arhus, Denmark.
authors.forename: P
authors.initials: P
authors.lastname: Faunø
authors.forename: O
authors.initials: O
authors.lastname: Suomalainen
authors.forename: D
authors.initials: D
authors.lastname: Bergqvist
authors.forename: H
authors.initials: H
authors.lastname: Fredin
authors.forename: K
authors.initials: K
authors.lastname: Kettunen
authors.forename: S
authors.initials: S
authors.lastname: Soimakallio
authors.forename: C
authors.initials: C
authors.lastname: Cederholm
authors.forename: P
authors.initials: P
authors.lastname: Karjalainen
authors.forename: H
authors.initials: H
authors.lastname: Vissinger
authors.forename: T
authors.initials: T
authors.lastname: Justesen
mesh_terms: D005340:Fibrinogen; D006620:Hip Fractures / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D006801:Humans; D007457:Iodine Radioisotopes; D008403:Mass Screening / Q000379:methods*; D010690:Phlebography; D011183:Postoperative Complications / Q000000981:diagnostic imaging; D011237:Predictive Value of Tests; D011877:Radionuclide Imaging; D013924:Thrombophlebitis / Q000000981:diagnostic imaging* / Q000209:etiology
chemical_list: D007457:Iodine Radioisotopes; D005340:Fibrinogen