[Acute promyelocytic leukemia developed in the course of systemic lupus erythematosus: a case report].
A-36-year old Japanese female who had been suffered from systemic lupus erythematosus (SLE) and treated with prednisolone for 3.5 years developed de novo acute promyelocytic leukemia (APL) without preleukemic state. She had a short period of complete remission in leukemia but she died with recurrence of leukemia. While malignant tumors including lymphoid malignancy have been shown to develop occasionally in the course of SLE, acute myelogenous leukemia (AML) following SLE is a very rare condition. Although combination of SLE and AML may be incidental, review of the literatures revealed some interesting insight into the pathogenesis of SLE and AML.
Taguchi
F
F
Third Department of Internal Medicine, Faculty of Medicine, Kyushu University.
Miyoshi
T
T
Nakajima
N
N
Nishimura
J
J
Nawata
H
H
D000328:Adult; D005260:Female; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000209:etiology*; D008180:Lupus Erythematosus, Systemic / Q000150:complications*