Development of pentamidine analogues as new agents for the treatment of Pneumocystis carinii pneumonia.
Tidwell
R R
RR
Department of Pathology, School of Medicine, University of North Carolina, Chapel Hill 27599-7525.
Jones
S K
SK
Geratz
J D
JD
Ohemeng
K A
KA
Bell
C A
CA
Berger
B J
BJ
Hall
J E
JE
D000818:Animals; D004271:DNA, Fungal / Q000378:metabolism; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D015195:Drug Design; D005872:Giardia / Q000187:drug effects; D066298:In Vitro Techniques; D007894:Leishmania mexicana / Q000187:drug effects; D008297:Male; D010419:Pentamidine / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology*; D010963:Plasmodium falciparum / Q000187:drug effects; D011010:Pneumocystis / Q000187:drug effects* / Q000235:genetics; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy*; D051381:Rats; D011919:Rats, Inbred Strains; D013329:Structure-Activity Relationship
D004271:DNA, Fungal; D010419:Pentamidine