[Antibiotic prophylaxis with piperacillin in vaginal hysterectomy. Study of 1 dose versus 3 doses].
A homogeneous and consecutive series of 93 patients treated with vaginal hysterectomy is studied in a controlled, randomized clinical essay. The patients were divided in two groups. One of the groups received one single dose of 49 of piperacillin 30 minutes before surgery; the other, three doses of 4 g of the same antibiotic 30 minutes before surgery and 6 & 12 hours after it. No significant difference was found between both groups and therefore it is fair to suppose that one single preoperative dose of piperacillin shows similar efficacy to the usually used three doses, one preoperative and two postoperative.
Cartañá
J
J
Servico de Ginecología, Hospital Son Dureta, Insalud, Palma de Mallorca.
Yárnoz
M C
MC
Ruiz de Gopegui
R M
RM
Mascaró
M
M
Cortés
J
J
D001424:Bacterial Infections / Q000517:prevention & control*; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007044:Hysterectomy; D010878:Piperacillin / Q000008:administration & dosage / Q000627:therapeutic use*; D011292:Premedication; D011446:Prospective Studies; D013530:Surgical Wound Infection / Q000517:prevention & control*
D010878:Piperacillin
Profilaxis antibiótica con piperacilina en la histerectomiá vaginal. Estudio de una dosis frente a tres.