title: [Treatment of nephrotic syndrome with cyclosporin A].
abstract: The authors treated eight children with corticoid dependent syndrome caused by minor abnormalities of the glomeruli with Cyclosporin A. They administered Cyclosporin, 5 mg/kg/24 h., for a period of 8-16 weeks. In three patients they used Cyclosporin A alone, 5 children were given in addition 10 mg Prednisone per day. They achieved complete remission in all patients. During treatment they monitored haematological and biochemical parameters as well as Cyclosporin A levels; before treatment and after its termination they examined also immunological indicators. They did not observe any serious side effects of treatment.
authors.affiliation: Detská klinika NsP Akademika L. Dérera, Bratislava.
authors.forename: K
authors.initials: K
authors.lastname: Furková
authors.forename: E
authors.initials: E
authors.lastname: Kaiserová
authors.forename: O
authors.initials: O
authors.lastname: Páleníková
authors.forename: I
authors.initials: I
authors.lastname: Hruskovic
authors.forename: I
authors.initials: I
authors.lastname: Slugen
authors.forename: D
authors.initials: D
authors.lastname: Arpasová
authors.forename: S
authors.initials: S
authors.lastname: Janota
authors.forename: S
authors.initials: S
authors.lastname: Nyulassy
mesh_terms: D002648:Child; D002675:Child, Preschool; D003524:Cyclosporins / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D009404:Nephrotic Syndrome / Q000188:drug therapy* / Q000276:immunology / Q000503:physiopathology
chemical_list: D003524:Cyclosporins
vernacular_title: Liecba nefrotického syndrómu cyklosporínom A.