title: SCID mice as immune system models.
abstract: C.B-17 scid/scid mice are born with severe combined immunodeficiency. This defect in the maturation of T and B cells has provided a novel experimental system in which to study normal lymphoid differentiation and function in mouse and man.
authors.affiliation: Systemix Inc., Palo Alto, California, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: McCune
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D006413:Hematopoietic System / Q000276:immunology; D006801:Humans; D007107:Immune System; D008221:Lymphoid Tissue / Q000276:immunology; D051379:Mice; D008817:Mice, Mutant Strains / Q000235:genetics / Q000276:immunology*; D008954:Models, Biological