title: Hematuria screening for bladder cancer.
abstract: Detection of bladder cancer before deep invasion occurs offers patients a favorable prognosis. Because most bladder cancers, even when noninvasive, produce hematuria, screening asymptomatic persons at risk for bladder cancer for hematuria provides a means of promoting early detection and has the potential to reduce morbidity and mortality. However, bladder cancer-induced hematuria is quite intermittent; thus, repetitive testing is necessary. In a pilot study, 11.4% of asymptomatic men over age 50 who had at least one positive dipstick result were found on urologic work-up to have bladder cancers that were caught early enough to receive purportedly curative treatment. Issues concerning the applicability of this methodology to other high-risk populations are discussed and efforts now underway to confirm and expand upon this screening program are described.
authors.affiliation: University of Wisconsin School of Medicine, Madison 53792.
authors.forename: E M
authors.initials: EM
authors.lastname: Messing
authors.forename: A
authors.initials: A
authors.lastname: Vaillancourt
mesh_terms: D000368:Aged; D006417:Hematuria / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009784:Occupational Diseases / Q000175:diagnosis* / Q000209:etiology; D011934:Reagent Strips; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000209:etiology
chemical_list: D011934:Reagent Strips