title: The management of liver metastases.
abstract: The spontaneous life expectancy of patients with liver metastases from colorectal cancers is dismaying. Surgical resection is the only treatment which may help these patients. After resection the 5-year survival rate averages 25%. The best results are obtained in patients with one or few metastases localized to one liver lobe. There is no effective adjuvant therapy. Systemic or regional chemotherapy and immunomodulation have little effect in patients with inoperable metastases.
authors.affiliation: Groupe de Recherche sur la Chirurgie du Foie et de l'Hypertension Portale, Université Paris XI, Hôpital Antoine Béclère, Clamart.
authors.forename: D
authors.initials: D
authors.lastname: Franco
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D015179:Colorectal Neoplasms / Q000150:complications*; D003131:Combined Modality Therapy; D006498:Hepatectomy / Q000592:standards*; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary / Q000628:therapy*; D012307:Risk Factors; D015996:Survival Rate
chemical_list: D007155:Immunologic Factors