[The acute and chronic action of ethanol on blood serum proteins in rats].
The results of electrophoresis of blood serum proteins (BSP) in rats evidence that degradation of lipoproteins and one polypeptide of the postalbumin zone was observed after a single administration of ethanol in a dose of 4 g/kg. A daily administration of ethanol for one month was attended by a quantitative redistribution of BSP fractions due to their aggregation. The comparison of the effects of ethanol and acetaldehyde suggests that the change in BSP spectra observed under long-term alcoholization is produced by acetaldehyde action and is connected with the formation of polypeptide complexes. At a single and long-term use of ethanol there were no changes in the concentrations of common BSP.
Bozhko
G Kh
GKh
Strelianaia
E I
EI
Voloshin
P V
PV
D000435:Alcoholic Intoxication / Q000097:blood; D000437:Alcoholism / Q000097:blood; D000818:Animals; D001797:Blood Protein Electrophoresis; D001798:Blood Proteins / Q000032:analysis / Q000187:drug effects*; D004591:Electrophoresis, Polyacrylamide Gel; D000431:Ethanol / Q000633:toxicity*; D051381:Rats
D001798:Blood Proteins; D000431:Ethanol
Ostroe i khronicheskoe deĭstvie étanola na belki syvorotki krovi krys.