title: [Hyposensitization: indications and expectations].
abstract: Allergy is the most frequent immunologic disorder in childhood. The prevalence of allergic complaints among children is estimated as about 10%. The diagnosis of an allergy takes the following factors into account: The patient's history, skin test, determination of total and specific IgE antibodies and a provocation test to a diseased organ. Hyposensitization is recommended for allergic patients without any significant improvement in spite of avoidance of allergen and in spite of pharmacologic therapy. Modified allergens/allergoids demonstrate a comparable efficacy as a conventional subcutaneous allergen immunotherapy. Measurement of specific IgE- and IgG-antibodies permits an evaluation of degree of sensitization and/or immune response to hyposensitization treatment.
authors.affiliation: Universitäts-Kinderklinik Freiburg, Bundesrepublik Deutschland.
authors.forename: R
authors.initials: R
authors.lastname: Urbanek
mesh_terms: D000485:Allergens / Q000008:administration & dosage / Q000276:immunology; D002648:Child; D003888:Desensitization, Immunologic / Q000379:methods*; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology / Q000628:therapy*; D007073:Immunoglobulin E / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis
chemical_list: D000485:Allergens; D007074:Immunoglobulin G; D007073:Immunoglobulin E
vernacular_title: Hyposensibilisierung: Indikation und Erwartungen.