Cross-reactivity of goat alloantisera lymphocyte antigens with ovine peripheral blood lymphocytes and erythrocytes.
Twenty-two alloantisera that detected eleven specificities in two loci of the goat (SD1 and SD2) were studied on ovine lymphocytes from 55 Spanish Merino sheep by microlymphocytotoxicity assay. All the sera detected antigenic variability in sheep although this variability was not comparable to that described in the goat. No pancytotoxic sera were found. Agglutinating and hemolytic antibodies present in the sera were not related to any antigen present in erythrocytes and lymphocytes. Furthermore these samples were typed with sixteen ovine alloantisera and no relationship between specificities detected by ovine sera and the antigenic variability detected by goat alloreactives was found.
Molina
A
A
Departamento de Genética, Universidad de Córdoba, Spain.
Moreno
A
A
Garrido
J J
JJ
Morera
L
L
Llanes
D
D
Millot
P
P
van Kooten
P S
PS
D000818:Animals; D000961:Antilymphocyte Serum / Q000276:immunology*; D003429:Cross Reactions; D004912:Erythrocytes / Q000276:immunology*; D006041:Goats / Q000276:immunology*; D007518:Isoantibodies / Q000276:immunology; D007519:Isoantigens / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology*; D012756:Sheep / Q000097:blood / Q000276:immunology*; D013045:Species Specificity
D000961:Antilymphocyte Serum; D007518:Isoantibodies; D007519:Isoantigens