[The effect of melatonin and epiphysectomy on the function of the mono-oxygenase system in rat liver].
After chronic melatonin administration (1 mg/kg, 14 days) the content of cytochrome P-450 and activity of NADPH: cytochrome c-reductase in rat microsomes were increased. Pinealectomized rats had opposite directed shifts in microsomal oxidation. In these animals activated effect of melatonin was absent.
Popov
A V
AV
Zarubin
V V
VV
Arushanian
E B
EB
Luneva
T M
TM
D000818:Animals; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D008862:Microsomes, Liver / Q000187:drug effects* / Q000201:enzymology; D010084:Oxidation-Reduction / Q000187:drug effects; D010105:Oxygenases / Q000187:drug effects* / Q000378:metabolism; D010870:Pineal Gland / Q000502:physiology* / Q000601:surgery; D051381:Rats
D010105:Oxygenases; D008550:Melatonin
Vliianie melatonina i épifizéktomii na sostoianie monooksigenaznoĭ sistemy pecheni krys.