[The induction of tumor necrosis factor and interleukin-1 under exposure to the glycopolymers isolated from Pseudomonas solanacearum and Clavibacter michiganense].
Lipopolysaccharide of Pseudomonas solanacearum and acid polysaccharides of Clavibacter michiganense are effective inductors of formation of the factor of tumour necrosis (TNF) and interleukin-1 (IL-1) by peritoneal macrophages of mice and their activity exceeds that of lipopolysaccharide Escherichia coli 055:B5 ("Sigma"). O-specific polysaccharide and lipid A are responsible for the capacity of liposaccharide molecule of P. solanacearum to induce TNF and IL-1.
Varbanets
L D
LD
Prokop'eva
E D
ED
Prokop'ev
A A
AA
Ketlinskiĭ
S A
SA
D000818:Animals; D001704:Biopolymers; D002478:Cells, Cultured / Q000187:drug effects / Q000378:metabolism; D007375:Interleukin-1 / Q000032:analysis / Q000096:biosynthesis*; D008070:Lipopolysaccharides / Q000302:isolation & purification / Q000494:pharmacology*; D008264:Macrophages / Q000187:drug effects / Q000378:metabolism; D051379:Mice; D010529:Peritoneal Cavity / Q000166:cytology; D011135:Polysaccharides, Bacterial / Q000302:isolation & purification / Q000494:pharmacology*; D011549:Pseudomonas; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis / Q000096:biosynthesis / Q000187:drug effects*
D001704:Biopolymers; D007375:Interleukin-1; D008070:Lipopolysaccharides; D011135:Polysaccharides, Bacterial; D014409:Tumor Necrosis Factor-alpha
Issledovanie induktsii faktora nekroza opukholi i interleĭkina-1 pod vozdeĭstviem glikopolimerov, vydelennykh iz Pseudomonas solanacearum i Clavibacter michiganense.