title: Effect of prostaglandin F2 alpha on the fertility of dairy cows after calving.
abstract: Three hundred and thirty-one dairy cows in six herds were used to study the effect of a single injection of 25 mg dinoprost, a prostaglandin F2 alpha derivative, administered eight days after calving on several indices of fertility. A detailed comparison was made between 113 treated cows and 113 control cows of the same parity, which had calved within seven days of each other on the same farm and had experienced the same degree of dystocia. In cows which had calved without assistance, the treatment reduced the mean interval between calving and first heat from 40 days to 37 days but increased the mean interval between calving and conception from 83 days to 85 days. In cows which had required assistance at calving, the treatment reduced the mean interval between calving and first heat from 44 days to 34 days and reduced the mean calving to conception interval from 86 days to 68 days. The cows which benefited most were those which had required assistance during their second, third or fourth calvings; their calving to conception intervals were shortened by 22.5 days. An average of 1.39 services was required to establish conception in the treated cows which calved unaided, with 70 per cent conceiving to the first service, compared with an average of 1.34 services per conception and a 72 per cent conception rate to first service for their untreated herdmates.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Department of Veterinary Clinical Science, University of Liverpool, Leahurst, Neston, South Wirral.
authors.forename: A J
authors.initials: AJ
authors.lastname: White
authors.forename: H
authors.initials: H
authors.lastname: Dobson
mesh_terms: D000818:Animals; D002417:Cattle / Q000502:physiology*; D002418:Cattle Diseases / Q000503:physiopathology; D015237:Dinoprost / Q000031:analogs & derivatives / Q000032:analysis / Q000494:pharmacology*; D004971:Estrus / Q000187:drug effects*; D005260:Female; D005298:Fertility / Q000187:drug effects*; D005306:Fertilization / Q000187:drug effects; D008892:Milk / Q000737:chemistry; D007744:Obstetric Labor Complications / Q000503:physiopathology / Q000662:veterinary; D010298:Parity; D049590:Postpartum Period / Q000187:drug effects*; D011247:Pregnancy; D011374:Progesterone / Q000032:analysis
chemical_list: C008228:15-keto-13,14-dihydroprostaglandin F2alpha; D011374:Progesterone; D015237:Dinoprost