Microtubule assembly is altered following covalent modification by the n-hexane metabolite 2,5-hexanedione.
Boekelheide
K
K
Department of Pathology and Laboratory Medicine, Brown University, Providence, RI 02912.
Eveleth
J
J
Neely
M D
MD
Sioussat
T M
TM
D000817:Anilino Naphthalenesulfonates / Q000494:pharmacology; D000818:Animals; D001665:Binding Sites; D002417:Cattle; D003078:Colchicine / Q000494:pharmacology; D006586:Hexanes / Q000378:metabolism / Q000633:toxicity*; D006588:Hexanones / Q000378:metabolism / Q000633:toxicity*; D066298:In Vitro Techniques; D008870:Microtubules / Q000187:drug effects* / Q000378:metabolism; D013696:Temperature; D014404:Tubulin / Q000378:metabolism
D000817:Anilino Naphthalenesulfonates; D006586:Hexanes; D006588:Hexanones; D014404:Tubulin; C026385:n-hexane; C035763:5,5'-bis(8-(phenylamino)-1-naphthalenesulfonate); C011269:2,5-hexanedione; D003078:Colchicine