[Changes in the flora of the oral cavity after oral topical antibiotics. Importance in antimicrobial prophylaxis in surgery of the neck and head].
A pilot study using 5 healthy adults was performed to assess the influence of topical antibiotics and antiseptics on oral flora. Samples of saliva were cultured before and after rinsing the mouth with several solutions: clindamycin, amoxyciclin + clavulanic, povidone-iodine and placebo. The results of this study suggest that, by reducing concentrations of oral flora, topical oral antibiotic prophylaxis is justified for patients having a high risk of developing a surgical infectious complications.
Ramos Macías
A
A
Servicio de ORL, Hospital Clínico Universitario de Salamanca.
de Miguel Martínez
I
I
del Cañizo Fernández-Roldán
A
A
Ibáñez Pérez
R
R
Benito García
L
L
D000278:Administration, Buccal; D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D004311:Double-Blind Method; D006801:Humans; D009055:Mouth / Q000187:drug effects* / Q000382:microbiology*; D010038:Otorhinolaryngologic Diseases / Q000601:surgery; D011292:Premedication
D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local
Análisis de las modificaciones en la flora de la cavidad bucal tras el uso de antibióticos tópicos orales. Importancia en la profilaxis antimicrobiana en cirugía de cabeza y cuello.