[Thrombosis of the portal vein as a complication of paroxysmal nocturnal hemoglobinuria].
A patient suffering nocturnal paroxysmal hemoglobinuria (HPN) associated with the recovery phase of a severe medullar aplasia, and who presented a thrombosis of the portal vein is described. The sudden appearance of fast growing splenomegaly with signs of hypersplenism was the sign that made us suspect of a portal thrombosis. The diagnosis was confirmed by an ultrasound and an angiographic study with DIVAS. The problems due to the thromboembolic complications of HPN are reviewed and the therapeutic possibilities are discussed.
Nicolás
J M
JM
Servicio de Hematología, Hospital Clínico, Universidad de Barcelona.
Cervantes
F
F
López-Guillermo
A
A
Quinteros
L
L
Rozman
C
C
D001855:Bone Marrow Diseases / Q000150:complications; D002648:Child; D005260:Female; D006457:Hemoglobinuria, Paroxysmal / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D011169:Portal Vein; D013927:Thrombosis / Q000175:diagnosis / Q000209:etiology*
Trombosis de la vena porta como complicación de la hemoglobinuria paroxística nocturna.