title: Langerhans cell histiocytosis of the spinal cord: a case report.
abstract: A 14-year-old boy with Langerhans cell histiocytosis of the spinal cord who presented with progressive enlarged bilateral inguinal masses, difficulty in urination, walking and paresthesia in the left lower extremity and perineum is reported. Radiographic studies and computerized axial tomography of T12 to L2 spines showed destruction of the vertebral body of L1 and left-sided paravertebral soft tissue mass extending into the vertebral canal with complete block of the dural sac at the level of L1 spine. The operative finding was an extradural mass at the anterolateral aspect of L1 to L2 spines. After surgical removal of the lesion and chemotherapy with vincristine, prednisolone, 6-MP and methotrexate for 15 months, his neurological deficit improved and there has been no evidence of recurrent disease during his two years follow-up. Langerhans cell histiocytosis is a possible cause of spinal cord compression or cauda equina syndrome and should be considered after excluding other more common causes.
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.
authors.forename: M
authors.initials: M
authors.lastname: Wongchanchailert
authors.forename: V
authors.initials: V
authors.lastname: Laosombat
authors.forename: N
authors.initials: N
authors.lastname: Phuenpathom
authors.forename: W
authors.initials: W
authors.lastname: Mitarnan
mesh_terms: D000293:Adolescent; D006646:Histiocytosis, Langerhans-Cell; D006801:Humans; D007796:Laminectomy; D008297:Male; D011379:Prognosis; D013118:Spinal Cord Diseases; D014057:Tomography, X-Ray Computed