Ultrastructural observations on transganglionic degeneration in trigeminal primary sensory neurons in the neonatal rat.
Transganglionic degeneration was studied ultrastructurally in the trigeminal nucleus caudalis of newborn rats 2-6 days after a transection of the infraorbital nerve. Darkened degenerating terminals containing more or less numerous vacuoles and darkened unmyelinated axons were observed already 2 days postoperatively, but became more frequent at 3 days survival, and again less frequent at 6 days survival. Degenerating myelinated axons were most frequent 6 days postoperatively. Another conspicuous finding was the appearance of degenerating cells, in less advanced stages interpreted as being neurons.
Arvidsson
J
J
Department of Anatomy, Karolinska Institutet, Stockholm, Sweden.
Swallinger
C
C
D000818:Animals; D000831:Animals, Newborn; D001369:Axons / Q000648:ultrastructure; D004721:Endoplasmic Reticulum / Q000648:ultrastructure; D005724:Ganglia / Q000502:physiology / Q000648:ultrastructure*; D009186:Myelin Sheath / Q000502:physiology; D009410:Nerve Degeneration / Q000502:physiology*; D009457:Neuroglia / Q000648:ultrastructure; D009475:Neurons, Afferent / Q000502:physiology / Q000648:ultrastructure*; D051381:Rats; D011919:Rats, Inbred Strains; D014278:Trigeminal Nuclei / Q000502:physiology / Q000648:ultrastructure*