title: [Effect of extracorporeal shock wave lithotripsy on renal function-an experience with the new type piezoelectric lithotripter, Therasonic].
abstract: Seventeen patients with renal stones and 17 patients with ureteral stones were treated using the newly developed piezoelectric shock wave lithotripter, THERASONIC. To determine the effect of shock wave on renal function, urinary N-acetyl-beta-D-glucosaminidase (NAG) activity, urinary beta 2 microglobulin (BMG) concentration, serum BMG concentration and creatinine clearance (Ccr) were measured. Urinary NAG activity and urinary BMG concentration in renal stone patients were significantly elevated immediately after the treatment and returned to the pretreatment value within 24 hours. Neither serum BMG nor Ccr showed significant change in any of the patients. Therefore, we conclude that the renal tubular damage, which is transient and subtle, is the effect of shock wave lithotripsy using THERASONIC machine.
authors.affiliation: Department of Urology, Saitama Medical School.
authors.forename: Y
authors.initials: Y
authors.lastname: Kageyama
authors.forename: H
authors.initials: H
authors.lastname: Kusuyama
authors.forename: Y W
authors.initials: YW
authors.lastname: Lu
authors.forename: H
authors.initials: H
authors.lastname: Nagashima
authors.forename: H
authors.initials: H
authors.lastname: Kase
authors.forename: S
authors.initials: S
authors.lastname: Araki
authors.forename: M
authors.initials: M
authors.lastname: Hobo
authors.forename: H
authors.initials: H
authors.lastname: Itoh
authors.forename: K
authors.initials: K
authors.lastname: Nakamura
authors.forename: M
authors.initials: M
authors.lastname: Katoh
mesh_terms: D000118:Acetylglucosaminidase / Q000652:urine; D003404:Creatinine / Q000378:metabolism; D005260:Female; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D007677:Kidney Function Tests; D008096:Lithotripsy / Q000295:instrumentation; D008297:Male; D008875:Middle Aged; D014545:Urinary Calculi / Q000503:physiopathology* / Q000628:therapy; D001613:beta 2-Microglobulin / Q000378:metabolism
chemical_list: D001613:beta 2-Microglobulin; D003404:Creatinine; D000118:Acetylglucosaminidase