title: In vitro remineralization of caries lesions treated with surface-active phosphates.
abstract: Intact human enamel was demineralized in vitro to obtain artificial caries lesions. Part of the lesions was then treated with different surface-active compounds and remineralized with a remineralizing solution. The other part of the lesions was de- and remineralized in the same way, but was not treated with a surface-active compound. The results indicate that none of the surface-active compounds do affect the remineralization of the caries lesions. Possible applications of the tested compounds in combination with fluoride, for the prevention of dental caries, are discussed.
authors.affiliation: Department of Biochemistry, University of Nijmegen, The Netherlands.
authors.forename: J M
authors.initials: JM
authors.lastname: Borggreven
authors.forename: P C
authors.initials: PC
authors.lastname: Lammers
authors.forename: T
authors.initials: T
authors.lastname: Hoeks
authors.forename: B
authors.initials: B
authors.lastname: Zwanenburg
authors.forename: F C
authors.initials: FC
authors.lastname: Driessens
mesh_terms: D003731:Dental Caries / Q000139:chemically induced*; D003743:Dental Enamel / Q000187:drug effects* / Q000378:metabolism; D006801:Humans; D008852:Microradiography; D008964:Molar, Third; D009943:Organophosphorus Compounds / Q000494:pharmacology*; D010710:Phosphates / Q000494:pharmacology*; D010742:Phospholipid Ethers / Q000494:pharmacology*; D013499:Surface Properties; D013501:Surface-Active Agents / Q000494:pharmacology*; D014089:Tooth Remineralization
chemical_list: D009943:Organophosphorus Compounds; D010710:Phosphates; D010742:Phospholipid Ethers; D013501:Surface-Active Agents; C069963:Glydip; C011479:hexadecyl phosphate; C018279:sodium phosphate