title: Guillain Barre syndrome in children: clinical manifestations, laboratory findings, and the results of steroid treatment.
abstract: We report 28 cases diagnosed as GBS in the Department of Child Health, Medical School, University of Indonesia, DR. Cipto Mangunkusumo General Hospital in 7 years period. There were 17 males and 11 females with a ratio of 1.5:1. The age ranged from 9 months to 9.5 years, with a mean age of 4.57 +/- 2.36 years. Twelve (42.86%) cases were preceded by acute respiratory infection, 8 (28.57%) cases by non specific fever, 1 (9.57%) case by gastrointestinal tract infection and 7 (25%) cases did not have any history of acute infection. The clinical manifestations were motor weakness (100%), cranial nerves involvement (14.29%) and disturbance of sensation (17.80%). Most cases (92.86%) showed albuminocytologic dissociation feature with the CSF protein content more than 40 mg/dl. The number of cells was less than 10 cells/mm3 in 96.43% of cases. The specific NCV feature (peripheral NCV decrease) was found in 96.15% of patients and only 1 patient (3.85%) showed normal peripheral NCV. The severity of the disease was in accordance with the prognosis later. Corticosteroid was not beneficial in the treatment of GBS.
authors.affiliation: Department of Child Health, Faculty of Medicine, University of Indonesia Jakarta.
authors.forename: S
authors.initials: S
authors.lastname: Ismael
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007214:Indonesia / Q000453:epidemiology; D007223:Infant; D008297:Male; D011129:Polyradiculoneuropathy / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology*; D011379:Prognosis; D012189:Retrospective Studies
chemical_list: D000305:Adrenal Cortex Hormones