Constitutional translocation t(1;17)(p36;q12-21) in a patient with neuroblastoma.
A constitutional chromosome translocation t(1;17)(p36;q12-21) is reported in a boy with neuroblastoma. This is the first description of a cytogenetic abnormality possibly predisposing to the development of neuroblastoma.
Laureys
G
G
Department of Pediatrics, University Hospital Gent, Belgium.
Speleman
F
F
Opdenakker
G
G
Benoit
Y
Y
Leroy
J
J
D000008:Abdominal Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D002675:Child, Preschool; D002871:Chromosome Banding; D002878:Chromosomes, Human, Pair 1; D002886:Chromosomes, Human, Pair 17; D005729:Ganglioneuroma / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D006801:Humans; D008297:Male; D008677:Metaphase; D009447:Neuroblastoma / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D014178:Translocation, Genetic; D014407:Tumor Cells, Cultured / Q000166:cytology