HLA antigen and ventilatory drive in Thais with chronic obstructive pulmonary disease.
Studies of HLA antigens in 15 Thai patients with chronic obstructive pulmonary disease revealed a significant increase in HLA-Bw 60 frequency in the group with low ventilatory drive to carbondioxide using unstimulated airway pressure. The finding suggests an immunogenetic role of HLA-Bw 60 on the control of ventilation in COPD.
Maranetra
N
N
Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Chandanayingyong
D
D
Bovornkitti
S
S
D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006680:HLA Antigens / Q000032:analysis* / Q000145:classification; D015235:HLA-B Antigens / Q000032:analysis; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D012119:Respiration
D006680:HLA Antigens; D015235:HLA-B Antigens; C081918:HLA-B60 antigen