title: Tryptophan 2,3-dioxygenase activity in turkey poults infected with Bordetella avium.
abstract: 1. Liver tryptophan 2,3-dioxygenase (TPO) activity was depressed significantly by the Bordetella avium infection localized in the trachea of the turkey poult. 2. Tryptophan, given orally, induced a significant increase in TPO activity in both control and infected poults. 3. Hydrocortisone induced TPO activity in the turkey in a dose dependent manner.
authors.affiliation: North Carolina State University, Department of Poultry Science, Raleigh 27695-7635.
authors.forename: A G
authors.initials: AG
authors.lastname: Yersin
authors.forename: F W
authors.initials: FW
authors.lastname: Edens
authors.forename: D G
authors.initials: DG
authors.lastname: Simmons
mesh_terms: D000818:Animals; D001885:Bordetella Infections / Q000188:drug therapy / Q000201:enzymology / Q000662:veterinary*; D003345:Corticosterone / Q000097:blood; D006854:Hydrocortisone / Q000627:therapeutic use; D008099:Liver / Q000201:enzymology; D011201:Poultry Diseases / Q000188:drug therapy / Q000201:enzymology*; D014364:Tryptophan / Q000627:therapeutic use; D014366:Tryptophan Oxygenase / Q000378:metabolism*; D014422:Turkeys
chemical_list: D014364:Tryptophan; D014366:Tryptophan Oxygenase; D003345:Corticosterone; D006854:Hydrocortisone