[Prenatal development and postnatal morbidity of newborn infants of HIV positive mothers].
Does the maternal HIV-infection itself influence fetal development and neonatal morbidity or are adverse effects related to maternal opiate and nicotine abuse? 17 neonates of HIV-positive women (7 drug users) and 37 controls (17 healthy and 21 opiate exposed newborns) were examined prospectively. A discriminant analysis showed that opiate and nicotine abuse during pregnancy were associated with fetal growth retardation and neonatal morbidity, while HIV-infection of the mother did not influence these parameters. Symptoms of an HIV-embryopathy were not seen.
Maas
U
U
Abteilung für Neonatologie, Universitäts-Klinikum Rudolf Virchow, Standort Charlottenburg, Freie Universität Berlin.
Kattner
E
E
Koch
S
S
Schfer
A
A
Obladen
M
M
D001724:Birth Weight; D005260:Female; D005317:Fetal Growth Retardation / Q000175:diagnosis*; D005865:Gestational Age; D006679:HIV Seropositivity / Q000151:congenital* / Q000175:diagnosis; D006801:Humans; D007231:Infant, Newborn; D007958:Leukocyte Count; D008691:Methadone / Q000009:adverse effects / Q000627:therapeutic use; D009357:Neonatal Abstinence Syndrome / Q000175:diagnosis; D009293:Opioid-Related Disorders / Q000150:complications / Q000534:rehabilitation; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D011446:Prospective Studies; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D015819:Substance Abuse, Intravenous / Q000150:complications / Q000534:rehabilitation
D008691:Methadone
Pränatale Entwicklung und postnatale Morbidität bei Neugeborenen HIV-positiver Mütter.