title: [The results of percutaneous transluminal coronary angioplasty in lesions with thrombi].
abstract: Previous studies have suggested that the results of coronary angioplasty are poorer when the attempted lesion has a thrombus associated. With the aim of assessing the results of coronary angioplasty in lesions with thrombus, 1,192 consecutive coronary lesions attempted were prospectively analyzed. Of these, 88 (7%) had associated an angiographic intraluminal filling defect consistent with thrombus (group I) and were compared with the remaining 1,104 lesions (93%) without thrombus (group II). Age (56 +/- 12 vs 59 +/- 10 years) was similar in both groups, but patients in group I required more frequently dilatation after a myocardial infarction (acute phase or following thrombolytic therapy) (36% vs 12%, p less than 0.005) but infrequently for stable angina (6% vs 21%, p less than 0.005). Left ventricular ejection fraction (60 +/- 13% vs 63 +/- 12%) and the number of diseased vessels (1.46 +/- 0.7 vs 1.58 +/- 0.8) were similar in groups I and II, respectively, but lesions in group I were less frequently located in the left anterior descending coronary artery (35% vs 53%, p less than 0.025). Furthermore, lesions in group I were more frequently total occlusions (35% vs 4%, p less than 0.001), and were more severe (94 +/- 6% vs 87 +/- 8%, p less than 0.005), eccentric (81% vs 54%, p less than 0.005), irregular (72% vs 32%, p less than 0.005) and more frequently located at bend points (31% vs 17%, p less than 0.05). Primary angiographic success was lower in group I (79% vs 92%, p less than 0.001) and, after dilatation, the incidence of luminal irregularities (34% vs 15%, p less than 0.001) and early reocclusion (10% vs 1%, p less than 0.05) was higher in this group. However, when patients presenting with total occlusions were excluded from both groups primary angiographic success was similar (90% vs 91%) for groups I and II, respectively. We conclude that: 1) Lesions with intracoronary thrombus usually present other unfavourable angiographic characteristics for dilatation. 2) Results of coronary angioplasty in lesions with thrombus are similar to those obtained in other lesions when totally occluded vessels are excluded.
authors.affiliation: Departamento de Cardiopulmonar, Hospital Clínico Universitario, Madrid.
authors.forename: F
authors.initials: F
authors.lastname: Alfonso
authors.forename: C
authors.initials: C
authors.lastname: Macaya
authors.forename: A
authors.initials: A
authors.lastname: Iñiguez
authors.forename: R A
authors.initials: RA
authors.lastname: Hernández
authors.forename: J
authors.initials: J
authors.lastname: Ferrero
authors.forename: C
authors.initials: C
authors.lastname: Herrero
authors.forename: A
authors.initials: A
authors.lastname: Fernández-Ortiz
authors.forename: J
authors.initials: J
authors.lastname: Casado
authors.forename: P
authors.initials: P
authors.lastname: Zarco
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D001241:Aspirin / Q000627:therapeutic use; D016009:Chi-Square Distribution; D003131:Combined Modality Therapy; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000628:therapy*; D004110:Diltiazem / Q000627:therapeutic use; D005069:Evaluation Studies as Topic; D006801:Humans; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000628:therapy; D011446:Prospective Studies
chemical_list: D004110:Diltiazem; D001241:Aspirin
vernacular_title: Resultados de la angioplastia coronaria transluminal percutánea en lesiones con trombos.