Multiple cytogenetic clones in a basal cell carcinoma.
Chromosome analysis of short-term culture of a basal cell carcinoma showed five clonal chromosome abnormalities, t(9;14)(q12 or q13;p11), del(1)(q23 or q25), trisomy 5, trisomy 7, and monosomy X. In addition, several nonclonal structural and numerical changes were seen in the tumor cells.
Kawasaki
R S
RS
Departamento de Biologia, UNESP Faculdade Regional de Medicina, São José do Rio Preto, Brazil.
Caldeira
L F
LF
André
F S
FS
Gasques
J A
JA
Castilho
W H
WH
Bozola
A R
AR
Thomé
J A
JA
Tajara
E H
EH
D000368:Aged; D002280:Basal Cell Carcinoma / Q000235:genetics / Q000473:pathology*; D002869:Chromosome Aberrations / Q000473:pathology; D025063:Chromosome Disorders; D002999:Clone Cells; D005260:Female; D006801:Humans; D007621:Karyotyping; D012878:Skin Neoplasms / Q000235:genetics / Q000473:pathology*