[Aztreonam and clindamycin in short-term antibiotic prophylaxis in colorectal surgery: results of a multicenter studies].
The Authors studied the effects of a short-term prophylaxis (Aztreonam + Clindamycin) administered to 259 patients operated on for colo-rectal diseases. Thirteen wound sepsis (5.15%) and 49 different infections (19.44%) occurred in this group of patients. The study confirms the link between P.N.I. greater than 50 and the incidence of wound infections. The incidence of urogenital sepsis was correlated with the catheterization period (greater than 6 days), operative time (greater than 200 min.), hospitalization (greater than 12 days) and age (greater than 70 years). General tolerance to the antibiotics was good.
Gardini
G
G
Divisione di Chirurgia O.C. Lugo.
Bernabè
A
A
Guglielminetti
D
D
Campanini
A
A
Orselli
F
F
Dell'Amore
D
D
Folli
S
S
Zattini
P S
PS
Prussiano
F
F
Pivi
P P
PP
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001398:Aztreonam / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000453:epidemiology; D002981:Clindamycin / Q000627:therapeutic use*; D003106:Colon / Q000601:surgery*; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000453:epidemiology; D011292:Premedication; D012007:Rectum / Q000601:surgery*; D012737:Sex Factors; D013530:Surgical Wound Infection / Q000453:epidemiology
D002981:Clindamycin; D001398:Aztreonam
Aztreonam e clindamicina nella profilassi antibiotica a breve termine in chirurgia colorettale: risultati di uno studio policentrico.