title: [The search for new antiparasitic agents. 3. The synthesis of haloid-containing sulfonamidobenzamides with a benzo-2,1,3-thiadiazole radical in the sulfonamide group and a study of their acute toxicity].
abstract: Sulfamidobenzamides containing benzo-2,1,3-thiadiazole ring in the sulfamide group were synthesized and examined for acute toxicity. All the compounds were shown to have low toxicity (when administered orally in a dose of 4 g/kg to mice), the above fact makes possible the search for agents with anthelminthic activity.
authors.forename: F S
authors.initials: FS
authors.lastname: Mikhaĭlitsyn
authors.forename: M N
authors.initials: MN
authors.lastname: Lebedeva
authors.forename: N P
authors.initials: NP
authors.lastname: Kozyreva
authors.forename: N D
authors.initials: ND
authors.lastname: Lychko
authors.forename: S K
authors.initials: SK
authors.lastname: Drusviatskaia
authors.forename: N A
authors.initials: NA
authors.lastname: Uvarova
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000138:chemical synthesis* / Q000633:toxicity; D001549:Benzamides / Q000138:chemical synthesis* / Q000633:toxicity; D005260:Female; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D013329:Structure-Activity Relationship; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000633:toxicity
chemical_list: D000871:Anthelmintics; D001549:Benzamides; D013449:Sulfonamides
vernacular_title: Izyskanie novykh protivoparazitarnykh sredstv. Soobshchenie 3. Sintez galoidsoderzhashchikh sul'fonamidobenzamidov s ostatkom benzo-2,1,3-tiadiazola v sul'fonamidnoĭ gruppe i izuchenie ikh ostroĭ toksichnosti.