Screening pregnant women for genital herpes.
Neonatal herpes leads to serious morbidity and high mortality. The true incidence is unknown due to under reporting and difficulties in diagnosing the condition, but may be increasing. Mothers with primary disease, at term, present a greater infection risk to their offspring than mothers with recurrent disease, but the exact risks remain unknown. Existing prevention policies are inefficient, time-consuming for the doctor and the patient and, where caesarean section is offered to at-risk mothers, potentially hazardous. Anti-viral therapy offers a rational alternative and requires urgent evaluation.
Mercey
D
D
Academic Department of Genito-Urinary Medicine, Middlesex Hospital, London, UK.
Mindel
A
A
D000212:Acyclovir / Q000627:therapeutic use; D005260:Female; D006558:Herpes Genitalis / Q000150:complications / Q000188:drug therapy / Q000517:prevention & control* / Q000635:transmission; D006801:Humans; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy / Q000517:prevention & control*
D000212:Acyclovir