Protective effect of ceruloplasmin against lipid peroxidation in blood platelets.
The effect of ceruloplasmin on the peroxidation of blood platelet lipids was tested. Using thiobarbituric acid reactivity for measuring lipid peroxidation it was shown that ceruloplasmin inhibited peroxidation of pig platelet lipids induced by UV-irradiation, and much less when enzymatic peroxidation was stimulated by thrombin.
Wachowicz
B
B
Department of Biochemistry, University of Lódź, Poland.
Krajewski
T
T
Zbikowska
H
H
D000818:Animals; D000975:Antioxidants; D001095:Arachidonic Acids / Q000097:blood*; D001792:Blood Platelets / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects; D002570:Ceruloplasmin / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects*; D008315:Malondialdehyde / Q000097:blood; D012709:Serum Albumin / Q000494:pharmacology; D013552:Swine; D013858:Thiobarbiturates; D013917:Thrombin / Q000494:pharmacology; D014466:Ultraviolet Rays
D000975:Antioxidants; D001095:Arachidonic Acids; D012709:Serum Albumin; D013858:Thiobarbiturates; D008315:Malondialdehyde; D002570:Ceruloplasmin; D013917:Thrombin; C029684:thiobarbituric acid