title: [Carcinoembryonic antigen (CEA) in ascites].
abstract: The diagnostic value of carcinoembryonic antigen (CEA) was studied prospectively in 18 patients with ascites of malignant and 28 patients with ascites of benign genesis. Both sensitivity and specificity reached 83%. With a prevalence of malignant disease of 38%, the positive and negative predictive values were 75% and 89%, respectively. In contrast to frequent false-positive CEA values in the serum of liver cirrhotics (48.3%), false-positive CEA values in the ascites of the same patients were observed in only 17.3%. It is thus recommended that if CEA determination is to be employed, it should be done in the ascites itself.
authors.affiliation: Medizinische Klinik, Ruhr-Universität Bochum.
authors.forename: C
authors.initials: C
authors.lastname: Coenen
authors.forename: G
authors.initials: G
authors.lastname: Schmidt
authors.forename: M
authors.initials: M
authors.lastname: Wegener
authors.forename: B
authors.initials: B
authors.lastname: Wedmann
authors.forename: K H
authors.initials: KH
authors.lastname: Bauer
authors.forename: D
authors.initials: D
authors.lastname: Ricken
mesh_terms: D001201:Ascites / Q000209:etiology*; D001202:Ascitic Fluid / Q000737:chemistry*; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D004067:Digestive System Neoplasms / Q000150:complications; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012680:Sensitivity and Specificity
chemical_list: D002272:Carcinoembryonic Antigen
vernacular_title: Karzinoembryonales Antigen (CEA) im Aszites.