title: [Compounds similar to acyclovir. VI. Synthesis of optically active 1',2'-seconucleosides].
abstract: A convenient method is suggested of synthesis of (3R, 4R)-, (3S, 4S)- and (3R/S, 4S/R)-dihydroxy-3-hydroxymethyl-2-oxapentyl derivatives of the, cytosine, uracyl, adenine and guanine ("full" acyclic analogues of nucleosides with C1'-C2' bond cleaved) by condensation of trimethylsilyl derivatives of nucleic bases (sodium salt in case of adenine) with (3$, 4R)-, (3S )-, (3S, 4S)- and (3R/S, 4S/R)-4,5-diacetoxy-3-acetoxymethyl-1-chloro-2-oxapentanes without catalyst followed by deacetylation.
authors.forename: I P
authors.initials: IP
authors.lastname: Smirnov
authors.forename: S V
authors.initials: SV
authors.lastname: Kochetkova
authors.forename: T L
authors.initials: TL
authors.lastname: Tsilevich
authors.forename: A A
authors.initials: AA
authors.lastname: Khorlin
authors.forename: B P
authors.initials: BP
authors.lastname: Gottikh
authors.forename: V L
authors.initials: VL
authors.lastname: Florent'ev
mesh_terms: D000212:Acyclovir / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D002942:Circular Dichroism; D009705:Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D009705:Nucleosides; D000212:Acyclovir
vernacular_title: Soedineniia, podobnye atsikloviru. VI. Sintez opticheski aktivnykh 1',2'-sekonukleozidov.