[The immunohistochemical demonstration of intracytoplasmic estradiol in colorectal neoplasms].
Intracytoplasmic estradiol content was studied retrospectively using immunohistochemical procedures in tissue samples from subjects suffering from colorectal cancer. The results obtained reveal the presence of intracytoplasmic estradiol in cancer tissue. In precancerous lesions this presence is rarer and inconstant. Estradiol was not detected in the healthy tissue examined. These data suggest that such tumours may depend to some degree on endocrine factors.
Arena
F
F
Istituto di Chirurgia Generale, Università degli Studi di Messina.
Faraone
V
V
Crisafulli
C
C
De Gaetano
C
C
Di Vincenzo
C
C
Bartolo
V
V
Di Mauro
S
S
D000236:Adenoma / Q000378:metabolism; D002277:Carcinoma / Q000378:metabolism*; D003111:Colonic Polyps / Q000378:metabolism; D015179:Colorectal Neoplasms / Q000378:metabolism*; D003593:Cytoplasm / Q000378:metabolism*; D004958:Estradiol / Q000378:metabolism*; D006801:Humans; D007150:Immunohistochemistry; D008207:Lymphatic Metastasis; D012189:Retrospective Studies
D004958:Estradiol
Evidenziazione immunoistochimica dell'estradiolo intracitoplasmatico nelle neoplasie del colon-retto.