11 beta-hydroxyandrostenedione in human amniotic fluid.
11 beta-Hydroxyandrostene-3,17-dione (11 beta-hydroxyandrostenedione), a potential marker for prenatal diagnosis of CAH, has been for the first time determined in amniotic fluid obtained from 68 women who later delivered children without endocrine disorders. Its concentration averaged 0.96 +/- 0.31 (S.D.) (range 0.48-1.85) nmol/l and did not depend on the fetal sex. There was mild, insignificant increase of these values along with duration of pregnancy.
Hampl
R
R
Research Institute of Endocrinology, Prague, Czechoslovakia.
Sulcová
J
J
Zwinger
A
A
Stárka
L
L
D000312:Adrenal Hyperplasia, Congenital / Q000175:diagnosis; D000653:Amniotic Fluid / Q000737:chemistry*; D000735:Androstenedione / Q000031:analogs & derivatives* / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D011296:Prenatal Diagnosis; D012016:Reference Values
D000735:Androstenedione; C003582:11-hydroxyandrostenedione