Passive secretory immunity against Salmonella typhimurium demonstrated with foster mouse pups.
Mice immunised by drinking water containing an Aro- mutant strain of Salmonella typhimurium produced intestinal IgA antibodies after a memory response which was demonstrated by measuring copro-antibodies. After oral challenge with a virulent strain of S. typhimurium, foster mouse pups placed with immunised mothers survived longer than control pups held with non-immunised mothers.
Shope
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SR
Department of Microbiology, Montana State University, Bozeman 59717.
Schiemann
D A
DA
D000818:Animals; D000831:Animals, Newborn; D000907:Antibodies, Bacterial / Q000096:biosynthesis; D002460:Cell Line; D004848:Epithelium / Q000276:immunology; D005260:Female; D007116:Immunization, Passive; D007071:Immunoglobulin A, Secretory / Q000096:biosynthesis*; D007413:Intestinal Mucosa / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D011247:Pregnancy; D012481:Salmonella Infections, Animal / Q000276:immunology*; D012486:Salmonella typhimurium / Q000276:immunology*
D000907:Antibodies, Bacterial; D007071:Immunoglobulin A, Secretory