title: [The effect of obzidan on the tolerance for physical loading of hypertension patients].
abstract: The effect of obsidan (propranolol) on the physical load tolerance was examined in 65 hypertensive patients up to 55 years of age treated for one year in outpatient conditions. The patients were classified into two groups: basic group of 45 patients with hypertension in initial II stage and a control group of 22 hypertensive patients. The basic group patients were treated in the course of one year with obsidan in doses of 80 up to 160 mg daily. The control group patients were treated irregularly with other hypotensive drugs. The dynamic indices were examined in rest and after physical load before and after treatment. The long-term treatment with obsidan led to an improvement of the general condition, effective lowering of the arterial pressure in rest and after physical load, increased tolerance to physical load, decreased double product.
authors.forename: A
authors.initials: A
authors.lastname: Kokutsov
authors.forename: L
authors.initials: L
authors.lastname: Petev
mesh_terms: D004341:Drug Evaluation; D005080:Exercise Test / Q000379:methods; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008875:Middle Aged; D010807:Physical Endurance / Q000187:drug effects* / Q000502:physiology; D011433:Propranolol / Q000627:therapeutic use*
chemical_list: D011433:Propranolol
vernacular_title: Vliianie na obzidan vŭrkhu toleransa na fizicheskoto natorvane pri bolni s khipertonichna bolest.