title: [False positive serological tests for Borrelia burgdorferi in patients with primary antiphospholipid syndrome].
abstract: Serological tests for Borrelia burgdorferi were carried out in a series of 27 patients with primary antiphospholipid syndrome (PAPLS). The results showed a 14% prevalence of false positive Lyme disease serology in this patient population. In patients with PAPLS and false positive serologic tests for Borrelia burgdorferi neurological involvement was significantly more common (p = 0.012, Fisher's exact test) than in patients with PAPLS without that finding. We insist on the possibility that patients with PAPLS may have false positive serological tests for Borrelia burgdorferi as measured by IFI with the resulting diagnostic error. In these cases, confirmation by other techniques such as ELISA or immunoblotting is recommended.
authors.affiliation: Servicio de Medicina Interna, Hospital General Vall d'Hebron, Barcelona.
authors.forename: A
authors.initials: A
authors.lastname: Selva O'Callaghan
authors.forename: J
authors.initials: J
authors.lastname: Ordi Ros
authors.forename: J M
authors.initials: JM
authors.lastname: Porcel Pérez
authors.forename: C
authors.initials: C
authors.lastname: Tolosa Vilella
authors.forename: R
authors.initials: R
authors.lastname: Jordana Comajuncosa
authors.forename: C
authors.initials: C
authors.lastname: Juste Sánchez
authors.forename: M
authors.initials: M
authors.lastname: Vilardell Tarrés
mesh_terms: D000328:Adult; D000906:Antibodies / Q000032:analysis*; D000907:Antibodies, Bacterial / Q000032:analysis*; D015748:Borrelia burgdorferi Group / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005189:False Positive Reactions; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D015151:Immunoblotting; D007136:Immunoglobulins / Q000032:analysis; D008193:Lyme Disease / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D010743:Phospholipids / Q000276:immunology*; D013577:Syndrome
chemical_list: D000906:Antibodies; D000907:Antibodies, Bacterial; D007136:Immunoglobulins; D010743:Phospholipids
vernacular_title: Serología falsamente positiva frente a Borrelia burgdorferi en pacientes con síndrome antifosfolípido primario.