In vitro activity of cefixime: correlation index between MIC and disc diffusion test.
In this study the in vitro antibacterial effects of cefixime are presented. Its activity was studied by evaluation of MICs, MBCs and the disc diffusion susceptibility method on Enterobacteriaceae, Staphylococcus aureus and Streptococcus pneumoniae. Moreover, the coefficient of correlation between MIC values and the disc diffusion susceptibility test was evaluated. The results support the wide antimicrobial activity of cefixime, which appears to be particularly effective against enterobacteria.
Focà
A
A
Institute of Microbiology, University of Reggio Calabria, Catanzaro, Italy.
Liberto
M C
MC
Berlinghieri
M C
MC
Matera
G
G
Puccio
R
R
Carbone
M
M
Fera
M T
MT
D000892:Anti-Infective Agents, Urinary / Q000494:pharmacology*; D020682:Cefixime; D002439:Cefotaxime / Q000031:analogs & derivatives* / Q000494:pharmacology; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests / Q000379:methods
D000892:Anti-Infective Agents, Urinary; D020682:Cefixime; D002439:Cefotaxime