Cytogenetic findings in six posterior uveal melanomas: involvement of chromosomes 3, 6, and 8.
Six posterior uveal melanomas were karyotyped after short-term culture. One had a normal chromosome complement; the remaining five had limited chromosome changes. Involvement of chromosomes 1 and 6 was noted in two and four cases, respectively, and three ciliary body tumours demonstrated both monosomy 3 and i(8q).
Sisley
K
K
Department of Experimental and Clinical Microbiology, Royal Hallamshire Hospital, Sheffield, United Kingdom.
Rennie
I G
IG
Cottam
D W
DW
Potter
A M
AM
Potter
C W
CW
Rees
R C
RC
D000368:Aged; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D002872:Chromosome Deletion; D025063:Chromosome Disorders; D002893:Chromosomes, Human, Pair 3; D002896:Chromosomes, Human, Pair 6; D002898:Chromosomes, Human, Pair 8; D006801:Humans; D007621:Karyotyping; D008545:Melanoma / Q000235:genetics* / Q000473:pathology; D008677:Metaphase; D008875:Middle Aged; D014604:Uveal Neoplasms / Q000235:genetics* / Q000473:pathology