Chicken IgY: utilizing the evolutionary difference.
Chicken antibodies offer advantages over traditional ones (e.g. rabbit antibodies) due to the evolutionary difference between these immunoglobulins. Chicken give better antibody response against conserved mammalian antigens, they do not react with rheumatoid factors, bacterial or mammalian Fc receptors and can reduce background reactions due to cross-reactivity of anti-IgG antibodies.
Larsson
A
A
Department of Medical and Physiological Chemistry, University of Uppsala, Sweden.
Sjöquist
J
J
D000818:Animals; D005075:Biological Evolution; D002645:Chickens / Q000276:immunology*; D003429:Cross Reactions; D007136:Immunoglobulins / Q000276:immunology*; D012217:Rheumatoid Factor / Q000276:immunology
C016512:IgY; D007136:Immunoglobulins; D012217:Rheumatoid Factor