[The value of radioimmunoassay of urinary hCG in an in vitro fertilization program].
Radio-immuno-assay estimations of urinary hCG were carried out with pharmacia Kit beta hCG Riact on 36 women who had received embryo transfers. The analysis was carried in order to try and find how and at what moment in time it is possible to diagnose very early a developing pregnancy after embryo transfer. In this work we have found that the mean level of urinary hCG was significantly higher (P less than 0.001) in women who became pregnant (group B) than in those who did not become pregnant (group A). The difference in mean hormone levels in these two groups became more marked in the following days. The time doubling of the hCG level varied between 1.21 and 3.24 days in group B. By the eighth day the level of urinary hCG was less in group B than in group A, probably due to rapid renal breakdown of hCG. In summary these results show that the level of urinary hCG estimated from the 11th day onwards after an embryo transfer repeated two or three days later makes it possible to detect early pregnancies.
Kalenga
M K
MK
Département de Gynécologie obstétrique, Université Catholique de Louvain, Bruxelles.
de Hertogh
R
R
Loumaye
E
E
Vankrieken
L
L
Thomas
K
K
D000328:Adult; D006063:Chorionic Gonadotropin / Q000097:blood / Q000378:metabolism / Q000652:urine*; D004624:Embryo Transfer; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000097:blood / Q000628:therapy / Q000652:urine*; D011863:Radioimmunoassay / Q000295:instrumentation / Q000379:methods / Q000592:standards*; D011933:Reagent Kits, Diagnostic / Q000592:standards; D013997:Time Factors
D006063:Chorionic Gonadotropin; D011933:Reagent Kits, Diagnostic
Intérêt du dosage immunoradiométrique de l'hCG urinaire dans un programme de fécondation in vitro.