[Calcium antagonists in the treatment of nephrogenic hypertension].
Monotherapy with calcium antagonists nifedipine, foridon and verapamil hydrochloride was assessed in 46 patients with chronic glomerulonephritis and arterial hypertension by hypotensive effect and changes in systemic and renal hemodynamics, water-electrolytic balance, renin-angiotensin system. It is shown that nifedipine and foridon act as peripheral vasodilators. A hypotensive effect manifested most potently in nifedipine administration. None of the drugs aggravated renal hemodynamics, elevated intraglomerular tension, activated renin-angiotensin system, promoted water and sodium retention. Calcium antagonists are thought a treatment of choice in management of nephrogenic hypertension.
Tareeva
I E
IE
Kutyrina
I M
IM
Galstian
G M
GM
Rogov
V A
VA
D000293:Adolescent; D000328:Adult; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D005921:Glomerulonephritis / Q000150:complications; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D006801:Humans; D006977:Hypertension, Renal / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D008875:Middle Aged; D009543:Nifedipine / Q000031:analogs & derivatives* / Q000627:therapeutic use*; D014700:Verapamil / Q000627:therapeutic use*
D002121:Calcium Channel Blockers; D014700:Verapamil; D009543:Nifedipine; C045912:ryodipine
Antagonisty kal'tsiia v lechenii nefrogennoĭ gipertenzii.