Reduction of neutrophil elastase load in the lungs of patients with emphysema by reducing neutrophil enzyme secretion or chemotaxis.
Cohen
A B
AB
Department of Medicine, University of Texas Health Center, Tyler 75710.
Girard
W
W
McLarty
J
J
Starcher
B
B
Davis
D
D
Stevens
M
M
Rosenbloom
J
J
Kucich
U
U
D002634:Chemotaxis, Leukocyte / Q000187:drug effects*; D003078:Colchicine / Q000494:pharmacology; D006801:Humans; D019272:Leukocyte Elastase; D008168:Lung / Q000201:enzymology*; D009240:N-Formylmethionine Leucyl-Phenylalanine / Q000494:pharmacology; D009504:Neutrophils / Q000187:drug effects* / Q000201:enzymology; D010196:Pancreatic Elastase / Q000032:analysis*; D011656:Pulmonary Emphysema / Q000188:drug therapy / Q000201:enzymology*
D009240:N-Formylmethionine Leucyl-Phenylalanine; D010196:Pancreatic Elastase; D019272:Leukocyte Elastase; D003078:Colchicine