title: [Cholestasis in liver transplantation: incidence and diagnostic significance].
abstract: Cholestasis is frequently encountered in human liver transplants. In a series of 82 liver fine-needle aspiration biopsies performed in 20 grafted patients, the incidence rate of cholestasis was 55%. Cholestasis may predominantly be localized in the hepatocyte cytoplasm, or in the biliary tree or in both sites. In our cases it was most frequently associated with acute rejection (53%), followed by preservation injuries (29%) and ciclosporin toxicity (12%), respectively. The severity and the chronologic distribution of cholestatic episodes seem to vary according to the other associated pathologic conditions.
authors.affiliation: Dipartimento di biopatologia umana dell'Università La Sapienza di Roma.
authors.forename: I
authors.initials: I
authors.lastname: Pecorella
authors.forename: A
authors.initials: A
authors.lastname: Ciardi
authors.forename: S
authors.initials: S
authors.lastname: Rahimi
authors.forename: U
authors.initials: U
authors.lastname: Di Tondo
mesh_terms: D001707:Biopsy, Needle; D002779:Cholestasis / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D015994:Incidence; D016031:Liver Transplantation; D011183:Postoperative Complications / Q000473:pathology*
vernacular_title: La colestasi nel trapianto di fegato: incidenza e significato diagnostico.