title: [Mitochondrial encephalomyopathy, lactic acidosis and features of cerebrovascular disorders].
abstract: A 12 year old girl with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke like episodes (MELAS) is reported. After a normal childhood, at 9 years of age she developed generalized and hemilateralized seizures. Posteriorly, these episodes became more frequent and were accompanied by headache, homonimous hemianopsia, ataxia, vomiting, photophobia, left hemiparesis, slurred speech and even convulsive status. Laboratory tests evidenced lactic acidosis, brain lucencies at CT Scan and ragged skeletal muscle fibers at muscle biopsy.
authors.affiliation: Departamento de Pediatría, Escuela de Medicina, Universidad Católica de Chile.
authors.forename: T
authors.initials: T
authors.lastname: Mesa
authors.forename: A
authors.initials: A
authors.lastname: Hoppe
authors.forename: M
authors.initials: M
authors.lastname: Soza
mesh_terms: D000140:Acidosis, Lactic / Q000209:etiology; D002648:Child; D004679:Encephalomyelitis / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D006801:Humans; D008931:Mitochondria, Muscle / Q000648:ultrastructure*; D009135:Muscular Diseases / Q000473:pathology; D013577:Syndrome; D014057:Tomography, X-Ray Computed
vernacular_title: Encefalomiopatía mitocondrial, acidosis láctica y apariencia de accidentes vasculares cerebrales.