Fatty acid beta-oxidation-dependent bioactivation of 5,6-dichloro-4-thia-5-hexenoate and analogs in isolated rat hepatocytes.
Fitzsimmons
M E
ME
Department of Pharmacology, University of Rochester, NY 14642.
Anders
M W
MW
D000818:Animals; D001711:Biotransformation; D002470:Cell Survival / Q000187:drug effects; D005227:Fatty Acids / Q000378:metabolism*; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D010084:Oxidation-Reduction; D010101:Oxygen Consumption / Q000187:drug effects; D011422:Propionates / Q000493:pharmacokinetics* / Q000633:toxicity; D051381:Rats
D005227:Fatty Acids; D011422:Propionates; C007354:S-(1,2-dichlorovinyl)-3-mercaptopropionic acid