title: [Structure and antitumor activity of polysaccharides from the micelles of Aspergillus oryzae].
abstract: Three polysaccharide fractions active against mammary gland adenocarcinoma Ca-755 in mice but inactive against sarcoma C-180 were isolated from Aspergillus oryzae strain 5214. The main fraction, extracted from the mycelium by cold dilute alkali in the presence of sodium borohydride, was shown to be linear (1----3)-a-D-glucopyranan (pseudonigeran) according to 13C NMR spectroscopy, partial acid hydrolysis and periodate oxidation data.
authors.forename: A N
authors.initials: AN
authors.lastname: Usov
authors.forename: F F
authors.initials: FF
authors.lastname: Blanko
authors.forename: V S
authors.initials: VS
authors.lastname: Ivanova
authors.forename: E N
authors.initials: EN
authors.lastname: Bedrina
authors.forename: S A
authors.initials: SA
authors.lastname: Firsova
authors.forename: L A
authors.initials: LA
authors.lastname: Sedakova
authors.forename: N S
authors.initials: NS
authors.lastname: Funtikova
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy; D000818:Animals; D000970:Antineoplastic Agents; D001230:Aspergillus / Q000378:metabolism*; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008325:Mammary Neoplasms, Experimental / Q000188:drug therapy; D051379:Mice; D011135:Polysaccharides, Bacterial / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D000970:Antineoplastic Agents; D011135:Polysaccharides, Bacterial
vernacular_title: Stroenie i protivopukholevaia aktivnost' polisakharidov iz mitseliia Aspergillus oryzae.