[The production and physicochemical characteristics of new pyridazinyl-3-methyl-4-phenylazo-5-pyrazolones].
The synthesis of eight new 1-(R-pyridazinil)-3-methyl-4-(R-phenylazo)-5-pyrazolone, the structure of which was confirmed by the results of the physicochemical analysis, is presented. The preliminary tests for determining their biological action have revealed a moderate antimicrobial activity.
Dorneanu
M
M
Disciplina chimie organică, Facultatea de stomatologie-farmacie, Institutul de Medicină şi Farmacie Iaşi.
Stefănescu
E
E
Radu
C
C
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D008826:Microbial Sensitivity Tests; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D011725:Pyridines / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship; D013424:Sulfanilamides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013844:Thiazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D011720:Pyrazoles; D011725:Pyridines; D013424:Sulfanilamides; D013844:Thiazoles
Obţinerea şi caracterizarea fizico-chimică a unor noi piridazinil-3-metil-4-fenilazo-5-pirazolone.