title: Myosin heavy chain isoform changes in rat diaphragm are induced by endurance training.
abstract: After rats were chronically exercised by endurance swimming, an augmentation of succinic dehydrogenase (SDH) activity in the diaphragm and the EDL muscle was observed. In addition, endurance training induced a decrease in the percentage of myosin heavy chain (MHC) IIb in the diaphragm, and a decrease in the percentage of HCIIb concomitant with an increase in the percentage of HCIId in the EDL muscle. These results indicate that endurance training induced not only an increase of the oxidative capacity but also an alteration in the expression of an MHC phenotype in the diaphragm and skeletal muscle.
authors.affiliation: Laboratory of Biomechanics and Physiology, College of General Education, Yamaguchi University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Sugiura
authors.forename: A
authors.initials: A
authors.lastname: Morimoto
authors.forename: Y
authors.initials: Y
authors.lastname: Sakata
authors.forename: T
authors.initials: T
authors.lastname: Watanabe
authors.forename: N
authors.initials: N
authors.lastname: Murakami
mesh_terms: D000818:Animals; D003964:Diaphragm / Q000378:metabolism*; D008297:Male; D009218:Myosins / Q000378:metabolism*; D010805:Physical Conditioning, Animal; D010807:Physical Endurance / Q000502:physiology*; D051381:Rats; D013385:Succinate Dehydrogenase / Q000378:metabolism
chemical_list: D013385:Succinate Dehydrogenase; D009218:Myosins