title: Stability of a novel dithranol ointment formulation, containing ascorbyl palmitate as an anti-oxidant.
abstract: An emulsifying ointment-based dithranol formulation is described which was, with the addition of 0.1% w/w ascorbyl palmitate, stable for 52 weeks at room temperature. This is in contrast to the more conventionally used dithranol in Lassar's paste, which is stable for only 4 weeks at room temperature. An emulsifying ointment-based paste was additionally more convenient to use since it was easier to apply and remove.
authors.affiliation: Pharmacy Department, Northwick Park Hospital, Harrow, Middlesex, U.K.
authors.forename: P J
authors.initials: PJ
authors.lastname: Weller
authors.forename: C M
authors.initials: CM
authors.lastname: Newman
authors.forename: K R
authors.initials: KR
authors.lastname: Middleton
authors.forename: S M
authors.initials: SM
authors.lastname: Wicker
mesh_terms: D000875:Anthralin / Q000008:administration & dosage*; D000975:Antioxidants; D001205:Ascorbic Acid / Q000031:analogs & derivatives*; D004355:Drug Stability; D009824:Ointments
chemical_list: D000975:Antioxidants; D009824:Ointments; D001205:Ascorbic Acid; C031226:6-O-palmitoylascorbic acid; D000875:Anthralin