title: A girl treated with growth hormone presenting with neuromyopathy as first sign of acute lymphoblastic leukemia.
abstract: An 11-year-old girl being treated with DNA-recombinant growth hormone therapy presented with proximal limb weakness. Laboratory studies were negative. A few months later she presented with acute lymphoblastic leukemia (ALL). A diagnosis of carcinomatous neuromyopathy was made. After successful treatment of the leukemia the symptoms subsided and did not recur.
authors.affiliation: Dept of Pediatrics, Free University Hospital, Amsterdam, The Netherlands.
authors.forename: T J
authors.initials: TJ
authors.lastname: de Grauw
authors.forename: H A
authors.initials: HA
authors.lastname: Delemarre-van der Waal
authors.forename: R J
authors.initials: RJ
authors.lastname: Odink
authors.forename: F C
authors.initials: FC
authors.lastname: de Waal
mesh_terms: D002648:Child; D004274:DNA, Recombinant / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D009468:Neuromuscular Diseases / Q000209:etiology*; D010907:Pituitary Hormones / Q000009:adverse effects / Q000627:therapeutic use*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000139:chemically induced / Q000150:complications*
chemical_list: D004274:DNA, Recombinant; D010907:Pituitary Hormones