title: Epidural fentanyl does not influence intravenous PCA requirements in the post-caesarean patient.
abstract: Forty ASA physical status I or II patients scheduled for elective Caesarean delivery were studied to determine the effect of epidural fentanyl on post-Caesarean delivery analgesic requirements as administered by intravenous patient-controlled analgesia (PCA). Following delivery of the infant, under epidural anaesthesia with lidocaine 2% with 1/200,000 epinephrine, patients were randomly assigned to receive either 10 ml of preservative-free normal saline via the epidural catheter or 100 micrograms of fentanyl with 8 ml preservative-free normal saline in a double-blinded fashion. On arrival in the post-anesthesia recovery room (PAR), patients were provided with intravenous PCA meperidine 12.5 mg every eight minutes as needed. Patients were visited at intervals over the next 24 hr to determine if any differences in narcotic requirements, demands for narcotics, or severity of pain were noted. No differences were observed in any values between the groups. It is concluded that a single bolus of epidural fentanyl does not provide an advantage for postoperative pain relief in this patient population.
authors.affiliation: Department of Anesthesiology, Yale University School of Medicine, New Haven, CT 06510.
authors.forename: F B
authors.initials: FB
authors.lastname: Sevarino
authors.forename: C
authors.initials: C
authors.lastname: McFarlane
authors.forename: R S
authors.initials: RS
authors.lastname: Sinatra
mesh_terms: D015360:Analgesia, Epidural; D016058:Analgesia, Patient-Controlled; D000762:Anesthesia Recovery Period; D002585:Cesarean Section / Q000009:adverse effects*; D003258:Consumer Behavior; D004311:Double-Blind Method; D005260:Female; D005283:Fentanyl / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007275:Injections, Intravenous; D008614:Meperidine / Q000008:administration & dosage / Q000627:therapeutic use*; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D013997:Time Factors
chemical_list: D008614:Meperidine; D005283:Fentanyl