Early and 3 months follow-up results in 22 adult patients undergoing percutaneous transvenous mitral valvuloplasty.
Between April 1988 and October 1989, 22 adult patients with isolated or predominant severe mitral stenosis underwent Percutaneous Transvenous Mitral Valvuloplasty (PTMV). In 20 patients, a transseptal double balloon technique was used; in the last 2 patients, dilatation was performed using the Inoué balloon. Immediately after the procedure, the mitral valve area (MVA) rose from 1.2 +/- 0.3 to 2.2 +/- 0.8 cm2 (p less than 0.0001) using the hemodynamic method and from 1.1 +/- 0.4 to 1.9 +/- 0.4 cm2 (p less than 0.0001) using a Doppler technique. The mean left atrial pressure decreased from 20.3 +/- 6.0 to 10.5 +/- 5.0 mm Hg (p less than 0.0001). After the procedure, severe mitral regurgitation or significant iatrogenic interatrial septum defect did not occur. Two cerebral accidents were observed. One patient had a severe stroke with aphasia and hemiplegia but recovered within 3 months. The other patient had a minor dysarthric event, which resolved completely after 24 hours. Three months follow-up data in 16 patients revealed that they all were in NYHA class I or II. Restenosis occurred in 1 case. In the whole group of patients the MVA calculated by Doppler examination was similar to immediately after PTMV (1.9 +/- 0.4 versus 1.9 +/- 0.7 cm2).
Benit
E
E
Department of Cardiology, University Hospital Gasthuisberg, Leuven.
De Geest
H
H
Denef
B
B
Van de Werf
F
F
D000328:Adult; D000368:Aged; D002404:Catheterization / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve; D008946:Mitral Valve Stenosis / Q000503:physiopathology / Q000628:therapy*