Incidence and characterization of Staphylococcus aureus from the tongues of children.
Three hundred and seven children who had no diseases other than dental disease were examined for their oral carriage of Staphylococcus aureus, the most common persistent human pathogen. Eighty-four percent of them were positive for staphylococci, and 33% were positive for S. aureus. Among the 100 strains of S. aureus isolated, 40 strains produced enterotoxin, and 19 strains produced exfoliative toxin. Their susceptibility to antibiotics was also investigated: Six strains demonstrated resistance to methicillin (MIC greater than or equal to 12.5 microgram/mL), and 50% of the isolates were borderline resistant (MIC of 3.13 to 6.25 micrograms/mL) to the drug. These data suggest that the mouths of children could be reservoirs of pathogenic S. aureus.
Miyake
Y
Y
Department of Microbiology, Hiroshima University School of Dentistry, Japan.
Iwai
T
T
Sugai
M
M
Miura
K
K
Suginaka
H
H
Nagasaka
N
N
D002675:Child, Preschool; D003030:Coagulase; D004768:Enterotoxins / Q000032:analysis; D005083:Exfoliatins / Q000032:analysis; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D008297:Male; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D009055:Mouth / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification*; D014059:Tongue / Q000382:microbiology*
D003030:Coagulase; D004768:Enterotoxins; D005083:Exfoliatins