Seminalplasmin, an antimicrobial protein from bovine seminal plasma, inhibits peptidoglycan synthesis in Escherichia coli.
Seminalplasmin, an antimicrobial protein from bovine seminal plasma, inhibited peptidoglycan synthesis in Escherichia coli in a concentration-dependent manner. The inhibition of peptidoglycan synthesis appears to be a cause rather than a consequence of growth inhibition as it was observed soon after the addition of the antibiotic even in E. coli cells whose growth was totally inhibited by chloramphenicol.
Chitnis
S N
SN
Centre for Cellular and Molecular Biology, Hyderabad, India.
Prasad
K S
KS
D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D002417:Cattle; D002701:Chloramphenicol / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D008297:Male; D010457:Peptidoglycan / Q000096:biosynthesis*; D011506:Proteins / Q000008:administration & dosage / Q000494:pharmacology*; D012661:Semen / Q000737:chemistry; D029607:Seminal Vesicle Secretory Proteins; D012669:Seminal Vesicles / Q000737:chemistry
D000900:Anti-Bacterial Agents; D010457:Peptidoglycan; D011506:Proteins; D029607:Seminal Vesicle Secretory Proteins; D002701:Chloramphenicol