title: [Kemantane pharmacokinetics in rats].
abstract: Pharmacokinetics of novel immunostimulating drug kamantane was studied by using gas-liquid chromatography in experiments on rats. It was found that kemantane biotransformed rapidly after oral administration with the forming of active metabolite. Kemantane and its metabolites are distributed rapidly from the blood to organs. The drug is eliminated from the organism of rats as metabolite.
authors.forename: S S
authors.initials: SS
authors.lastname: Boĭko
authors.forename: V P
authors.initials: VP
authors.lastname: Zherdev
authors.forename: A A
authors.initials: AA
authors.lastname: Dvorianinov
authors.forename: I
authors.initials: I
authors.lastname: Janku
authors.forename: E
authors.initials: E
authors.lastname: Buchar
mesh_terms: D000218:Adamantane / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D000276:Adjuvants, Immunologic / Q000032:analysis / Q000493:pharmacokinetics*; D000818:Animals; D002849:Chromatography, Gas; D006207:Half-Life; D008297:Male; D051381:Rats; D013997:Time Factors
chemical_list: D000276:Adjuvants, Immunologic; C068220:kemantane; D000218:Adamantane
vernacular_title: Farmakokinetika kemantana u krys.