title: Neosartorya fischeri var fischeri (Wehmer) Malloch and Cain 1972 (anamorph: Aspergillus fischerianus Samson and Gams 1985) as a cause of mycotic keratitis.
abstract: The first case of mycotic keratitis caused by Neosartorya fischeri var. fischeri the teleomorph of Aspergillus fischerianus, is described. The patient, a 62-year-old man, had no history of trauma to his infected left eye. The infection progressed despite treatment with ketoconazole and the eye had to be eviscerated. Histological studies revealed the presence of hyaline, septate mycelium in the eye tissue. Cultures gave rise to a thermotolerant mould that developed both its asexual and sexual forms. The isolate was identified on the basis of the morphologic features of its anamorphic and teleomorphic states. In the literature only seven other species of Aspergillus have been unequivocally reported as causing mycotic keratitis.
authors.affiliation: Ospedale Maria Paternò Arezzo, Ragusa, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Coriglione
authors.forename: G
authors.initials: G
authors.lastname: Stella
authors.forename: L
authors.initials: L
authors.lastname: Gafa
authors.forename: G
authors.initials: G
authors.lastname: Spata
authors.forename: S
authors.initials: S
authors.lastname: Oliveri
authors.forename: A A
authors.initials: AA
authors.lastname: Padhye
authors.forename: L
authors.initials: L
authors.lastname: Ajello
mesh_terms: D001228:Aspergillosis / Q000188:drug therapy; D001230:Aspergillus / Q000254:growth & development / Q000302:isolation & purification; D003315:Cornea / Q000382:microbiology; D015353:Eye Enucleation; D015821:Eye Infections, Fungal / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D007634:Keratitis / Q000188:drug therapy / Q000382:microbiology*; D007654:Ketoconazole / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D014822:Vitreous Body / Q000382:microbiology
chemical_list: D007654:Ketoconazole