title: [Chemical burn caused by povidone-iodine].
abstract: Povidone-iodine (PVP-I) is a widely used antiseptic because of its low toxicity and high germicidal effect. A one-year-old boy who had undergone Nissen's fundoplication developed a chemical burn on his back postoperatively. The lesion was exposed to the surgical sheet immersed with a large amount of 10% PVP-I solution for 4 hours. Patch test with PVP-I (small aluminum chamber keeps a wet paper with PVP-I) revealed positive response in the patient. The same patch tests were performed in 17 volunteers. Sixteen subjects showed positive and one negative, while direct painting of a small quantity of PVP-I on skin without the chamber produced negative responses. This may indicate that prolonged exposure to wet PVP-I is harmful. It is important to use PVP-I carefully for the prevention of contact dermatitis.
authors.affiliation: Department of Anesthesiology, Osaka Medical Center.
authors.forename: S
authors.initials: S
authors.lastname: Nakano
authors.forename: A
authors.initials: A
authors.lastname: Uchiyama
authors.forename: H
authors.initials: H
authors.lastname: Ueyama
authors.forename: M
authors.initials: M
authors.lastname: Nishimura
authors.forename: C
authors.initials: C
authors.lastname: Tashiro
authors.forename: T
authors.initials: T
authors.lastname: Azuma
mesh_terms: D002057:Burns, Chemical / Q000209:etiology*; D006801:Humans; D007223:Infant; D008297:Male; D011206:Povidone-Iodine / Q000009:adverse effects*
chemical_list: D011206:Povidone-Iodine