title: [A new approach for transfusion of neocytes: the Neocel system].
abstract: Young red cells (neocytes) were prepared in a double transfer pack having a long, narrow separation bag that allows for a density gradient column to be established during centrifugation. The lighter fraction of red cells (neocyte fraction) was then expressed into a second delivery bag. Phthalate ester density distribution curves showed that 87.1% of the neocyte units had greater than 85% enrichment, i.e. more than 85% of the cells had densities lower than the midpoint density of the original red cell unit, thalassemic patients receiving neocytes had an average decrease of 21.1% in red cells per kg/yr as compared to their frozen red cell requirement, and an average of 6.9% fewer transfusions.
authors.affiliation: Department of Medicine, Children's Hospital, Boston, Massachusetts.
authors.forename: S V
authors.initials: SV
authors.lastname: Kevy
authors.forename: M S
authors.initials: MS
authors.lastname: Jacobson
authors.forename: M
authors.initials: M
authors.lastname: Fosburrg
authors.forename: M
authors.initials: M
authors.lastname: Renaud
authors.forename: A
authors.initials: A
authors.lastname: Scanlon
authors.forename: R
authors.initials: R
authors.lastname: Carmen
authors.forename: E
authors.initials: E
authors.lastname: Nelson
mesh_terms: D001803:Blood Transfusion / Q000379:methods; D002469:Cell Separation / Q000379:methods; D002470:Cell Survival; D017707:Erythrocyte Transfusion; D004912:Erythrocytes / Q000166:cytology*; D006801:Humans; D013789:Thalassemia / Q000628:therapy
vernacular_title: Une nouvelle approche pour la transfusion de néocytes: le système Néocel.