Dandy-Walker malformation in the Meckel syndrome.
The Meckel syndrome is an autosomal recessive condition and includes a heterogeneous group of CNS malformations, most frequently occipital encephalocele. We report on 2 sibs and one other unrelated case with Meckel syndrome in whom the CNS anomaly was the Dandy-Walker malformation, an association not previously described. The criteria used to diagnose the Meckel syndrome are also reviewed.
Herriot
R
R
Department of Immunology, Western Infirmary, Glasgow, Scotland.
Hallam
L A
LA
Gray
E S
ES
D000015:Abnormalities, Multiple / Q000235:genetics* / Q000473:pathology; D003616:Dandy-Walker Syndrome / Q000235:genetics* / Q000473:pathology; D004677:Encephalocele / Q000235:genetics*; D005260:Female; D005385:Fingers / Q000002:abnormalities; D005808:Genes, Recessive; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D007690:Polycystic Kidney Diseases / Q000235:genetics