title: Mucorales and deferoxamine: from saprophytic to pathogenic state.
abstract: Rhinocerebral mucormycosis can be a rapidly fatal course disease if the institution of treatment is delayed. We describe a case of a long-term dialysis patient in which the role of a siderophore such as Deferoxamine in promoting mucormycosis is discussed. The frequent lack of early diagnosis, itself subsequent to a break away from the standard diagnostic tools (apart from biopsy and culture) makes the survival prognosis particularly critical.
authors.affiliation: ENT Dept., Brugmann University Hospital.
authors.forename: L
authors.initials: L
authors.lastname: Vandevelde
authors.forename: C
authors.initials: C
authors.lastname: Bondewel
authors.forename: M
authors.initials: M
authors.lastname: Dubois
authors.forename: M
authors.initials: M
authors.lastname: De Vuyst
mesh_terms: D003676:Deferoxamine / Q000009:adverse effects*; D015521:Ethmoid Sinusitis / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000601:surgery; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000175:diagnosis* / Q000601:surgery; D011379:Prognosis; D006435:Renal Dialysis / Q000009:adverse effects; D012851:Sinus Thrombosis, Intracranial / Q000209:etiology*; D014057:Tomography, X-Ray Computed
chemical_list: D003676:Deferoxamine