title: [Management of vesicoureteral reflux in patients with neurogenic bladder dysfunction].
abstract: We studied 20 cases of neurogenic bladder with vesico-ureteral reflux retrospectively. Seven patients voided with Valsalva's maneuver and 12 patients were managed with clean intermittent catheterization, but one patient required permanent urinary diversion because of uncontrollable urinary tract infection. The patients were followed by intravenous pyelography, radioisotope renogram, voiding cystourethrography, determination of serum creatinine level and urodynamic study. Anti-reflux surgery was performed in 22 ureters and reflux resolved in 19 ureters. Among 12 ureters not treated by anti-reflux surgery, reflux disappeared in 5 ureters and improved in 2 ureters. Of 5 ureters, reflux resolved after clean intermittent catheterization in 2 ureters, and remained stable without recurrent infection or renal deterioration in the remaining 5 ureters. Regardless whether antireflux surgery was done or not, most of the patients who had high grade reflux and obstructive renal damage on radioisotope examinations had marked low compliance bladders. Our experience suggested the necessity of a suitable treatment to improve bladder compliance before considering anti-reflux surgery.
authors.affiliation: Department of Urology, Kinki University, School of Medicine, Osaka, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Onishi
authors.forename: A
authors.initials: A
authors.lastname: Uchida
authors.forename: H
authors.initials: H
authors.lastname: Kiwamoto
authors.forename: A
authors.initials: A
authors.lastname: Esa
authors.forename: T
authors.initials: T
authors.lastname: Sugiyamka
authors.forename: Y
authors.initials: Y
authors.lastname: Park
authors.forename: T
authors.initials: T
authors.lastname: Akiyama
authors.forename: T
authors.initials: T
authors.lastname: Kurita
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007668:Kidney / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011866:Radioisotope Renography; D012189:Retrospective Studies; D001750:Urinary Bladder, Neurogenic / Q000150:complications*; D014546:Urinary Catheterization / Q000379:methods*; D014547:Urinary Diversion; D014563:Urodynamics; D014567:Urography; D014718:Vesico-Ureteral Reflux / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*