title: [The prevention of neurotoxic reactions during the treatment of pulmonary tuberculosis in middle-aged and elderly patients].
abstract: To prevent and control neurotoxic reactions in the treatment of pulmonary tuberculosis in elderly and old patients the author used dipromonium (derivative of pangamic acid). Use of this agent at the beginning of the treatment course reduced the incidence of side-effects of neurotoxic character. In case of development of reactions of the central and peripheral nervous system dipromonium treatment resulted in their weakening or liquidation.
authors.forename: E F
authors.initials: EF
authors.lastname: Markova
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000187:drug effects*; D000995:Antitubercular Agents / Q000009:adverse effects / Q000627:therapeutic use; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009420:Nervous System / Q000187:drug effects*; D000644:Quaternary Ammonium Compounds / Q000627:therapeutic use; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents; D000644:Quaternary Ammonium Compounds; C001002:diisopropylamine dichloroacetate
vernacular_title: Preduprezhdenie neĭrotoksicheskikh reaktsiĭ pri lechenii tuberkuleza legkikh u bol'nykh pozhilogo i starcheskogo vozrasta.