title: [The effect of tocopherol and nicotinic acid on the microcirculation and blood coagulability in patients with ischemic heart disease].
abstract: Patients with ischemic heart disease were treated by routine techniques (53), using also tocopherol acetate (54) and combination of tocopherol with nicotinic acid (53). Changes of the microcirculatory bed of the bulbar conjunctiva was studied biomicroscopically and in the process of blood coagulation hemoelectrocoagulographically. Complex treatment using tocopherol acetate produced a positive effect on the coagulation properties of the blood and did essentially influence the fibrinolytic activity and microcirculation. Tocopherol plus nicotinic acid resulted in normalization of the blood coagulation process, favoured activation of fibrinolysis and improvement of the microcirculatory bed.
authors.forename: N N
authors.initials: NN
authors.lastname: Chernomorets
authors.forename: G V
authors.initials: GV
authors.lastname: Kotlubeĭ
authors.forename: N T
authors.initials: NT
authors.lastname: Vatutin
authors.forename: I A
authors.initials: IA
authors.lastname: Zhivotovskaia
authors.forename: V B
authors.initials: VB
authors.lastname: Gnilitskaia
authors.forename: R E
authors.initials: RE
authors.lastname: Alifanova
authors.forename: E Ia
authors.initials: EIa
authors.lastname: Lobach
authors.forename: N V
authors.initials: NV
authors.lastname: Mal'tseva
authors.forename: A N
authors.initials: AN
authors.lastname: Mitrofanov
mesh_terms: D000328:Adult; D000368:Aged; D001777:Blood Coagulation / Q000187:drug effects*; D003228:Conjunctiva / Q000098:blood supply*; D003327:Coronary Disease / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D006801:Humans; D008833:Microcirculation / Q000187:drug effects; D008875:Middle Aged; D009525:Niacin / Q000627:therapeutic use*; D024505:Tocopherols; D014810:Vitamin E / Q000031:analogs & derivatives* / Q000627:therapeutic use; D024502:alpha-Tocopherol / Q000031:analogs & derivatives*
chemical_list: D014810:Vitamin E; D009525:Niacin; D024502:alpha-Tocopherol; D024505:Tocopherols
vernacular_title: Vliianie tokoferola i nikitinovoĭ kisloty na mikrotsirkuliatsiiu i svertyvaemost' krovi u bol'nykh ishemicheskoĭ bolezn'iu serdtsa.