title: [The forensic medical aspects of the toxicokinetics of organophosphate insecticides].
abstract: The article deals with analysis of toxicokinetics of organophosphorous compounds (malathion and trichlorfon) in blood and of its changes in critical situations (shock, coma). In these forms of viability disturbances provided for mass-transfer and accumulation of poisonous substances in gastrointestinal tract their kinetics was shown to decelerate substantially. Active detoxification therapy improves markedly the parameters of organophosphorous insecticide kinetics. The parameters of toxicokinetics were recommended for use as objective criteria in estimation of intoxication gravity and therapy efficacy.
authors.forename: V N
authors.initials: VN
authors.lastname: Dagaev
authors.forename: A I
authors.initials: AI
authors.lastname: Iskandarov
mesh_terms: D000208:Acute Disease; D005554:Forensic Medicine; D006207:Half-Life; D006801:Humans; D008294:Malathion / Q000097:blood / Q000493:pharmacokinetics* / Q000506:poisoning; D013997:Time Factors; D014236:Trichlorfon / Q000097:blood / Q000493:pharmacokinetics* / Q000506:poisoning
chemical_list: D014236:Trichlorfon; D008294:Malathion
vernacular_title: Sudebno-meditsinskie aspekty toksikokinetiki fosfororganicheskikh insektitsidov.