Ideas in pathology. Focal and segmental glomerulosclerosis.
Focal and segmental glomerulosclerosis (FGS) is an important cause of the nephrotic syndrome and renal failure in children and adults. This review will present a detailed description of the pathological and clinical features of FGS and discuss in depth the modern concepts of its pathogenesis, which recent studies indicate is multifactorial and analogous to that of atherosclerosis.
Magil
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AB
Department of Pathology, University of British Columbia, Canada.
D005923:Glomerulosclerosis, Focal Segmental / Q000209:etiology / Q000473:pathology* / Q000503:physiopathology*; D006801:Humans