Distribution of acetylcholinesterase--and monoamine oxidase--positive neurons in pancreatic tissue transplant.
Acetylcholinesterase-and monoamine oxidase-positive neuronal elements were investigated in embryonic pancreatic tissue fragments transplanted into the anterior eye-chamber of rats for 28, 77, and 135 d, using enzyme histochemical method. Amongst the components of the parenchymal tissue, only the ductal and islets cells survived. Monoamine oxidase (MAO)- and acetylcholinesterase (AChE)-positive neuronal cell bodies and fibres were found to be considerably many in the surviving and newly formed islets of Langerhans, in the wall and periphery of the tubules. Their topography with regards to these components is similar to that in normal tissue. In normal tissue, MAO-positive fibers abut the basal and lateral parts of acinar cells. AChE-positive neurons are most conspicuous in the islets and in the wall of pancreatic ducts.
Adeghate
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1st Department of Anatomy, Histology and Embryology, Semmelweis University Medical School, Budapest, Hungary.
Donáth
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D000110:Acetylcholinesterase / Q000378:metabolism*; D000818:Animals; D000869:Anterior Eye Segment / Q000502:physiology; D005260:Female; D006651:Histocytochemistry; D008995:Monoamine Oxidase / Q000378:metabolism*; D009474:Neurons / Q000201:enzymology*; D010179:Pancreas / Q000201:enzymology / Q000294:innervation*; D016035:Pancreas Transplantation; D011247:Pregnancy; D051381:Rats; D014184:Transplantation, Homologous
D008995:Monoamine Oxidase; D000110:Acetylcholinesterase