[Hydrophobic and adhesive capacity of Candida strains isolated from patients with fungal infection].
The aim of this study was to evaluate hydrophobicity of fungal strains of Candida sp. isolated from clinical materials of patients with fungal infections. Two hundred and eighty one strains of C. albicans and 29 strains belonging to the other species of Candida were tested in salt aggregation test (SAT). Strong hydrophobicity (autoaggregation in the test) was found in 29.4% of tested strains. The majority of them was isolated from vagina. In 20 randomly selected strains hydrophobicity was measured not only by salt aggregation test but also by hydrophobic interaction chromatography (MIC). The ability to attach to buccal epithelial cells in vitro was compared between 50 strongly hydrophobic strains and 30 with low hydrophobicity. The former strains attached significantly stronger (p less than 0.001).
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Instytut Mikrobiologii AM w Krakowie.
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D000042:Absorption; D000268:Adhesiveness; D002175:Candida / Q000472:pathogenicity / Q000502:physiology*; D002177:Candidiasis / Q000209:etiology / Q000382:microbiology*; D002610:Cheek; D002847:Chromatography, Agarose / Q000379:methods; D006801:Humans; D066298:In Vitro Techniques; D009061:Mouth Mucosa / Q000382:microbiology*; D013499:Surface Properties; D014867:Water / Q000378:metabolism
D014867:Water
Hydrofobowość i zdolność adherencji szczepów Candida wyizolowanych od ludzi chorych na grzybice.