Demographic, social and clinical correlates of Raynaud phenomenon.
Our study has identified the demographic, social and clinical correlates of primary Raynaud phenomenon (RP) from a case-control study involving 235 subjects who were identified from a population-based prevalence survey of RP. All potential cases and a sampling of probable non-cases, identified by a screening questionnaire, were invited to a medical clinic for diagnostic testing and assignment of case or control status. Odds ratios (OR) for risk indicators for primary RP were estimated using multiple logistic regression to obtain 95% confidence intervals. The regression yielded statistically significant (p less than 0.05) positive associations for sex (OR = 3.0 for females versus males), self-reported alcohol use (OR = 1.1) and diastolic blood pressure (OR = 1.2) in those on antihypertensive medication. A significant (p = less than 0.01, OR = 0.4) negative association was found for Quetelet index (a measure of obesity). Near-significant or suggestive but non-significant negative associations were found between RP and marital status (p = 0.05, OR = 2.5), increased years of education and, for those on antihypertensive medication, higher systolic blood pressure (both p = 0.07).
Keil
J E
JE
Department of Biometry, Medical University of South Carolina, Charleston 29425.
Maricq
H R
HR
Weinrich
M C
MC
McGregor
A R
AR
Diat
F
F
D000428:Alcohol Drinking / Q000009:adverse effects; D001835:Body Weight; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011928:Raynaud Disease / Q000453:epidemiology / Q000209:etiology*; D012307:Risk Factors; D013022:South Carolina / Q000453:epidemiology