title: [Common antigenic components in soluble antigens shared by Schistosoma japonicum eggs and Paragonimus westermani adult worms].
abstract: Using enzyme-linked immunoblot technique (ELIB), the antigenic protein components of water-soluble and urea-soluble antigens of Schistosoma japonicum eggs (JSEA, JEAU) and Paragonimus westermani adult worms (PAA, PAA-U) were analysed. The results showed that in both JSEA and JEA-U, 8 and 3 bands of polypeptides could be recognized by sera from patients with schistosomiasis japonica (Sj). In both PAA and PAA-U, there were 9 and 2 bands of polypeptides respectively, which could be recognized by sera from patients with pagumogonimiasis skrjabini (Ps). The components of 36/37kDa in PAA and 20/21 kDa in JSEA were identified to be shared antigenic fractions existing between the two species of trematodes, which gave positive reaction against patient's sera from both S.j. and P.s., while PAA-U caused the reaction only with sera from patients with acute schistosomiasis. PAA-U might be useful to avoid cross reaction in the majority of schistosomiasis patients in the fields.
authors.affiliation: Research Laboratory of Parasitology, Hunan Medical College.
authors.forename: Q R
authors.initials: QR
authors.lastname: Zeng
authors.forename: W C
authors.initials: WC
authors.lastname: Zhang
authors.forename: C E
authors.initials: CE
authors.lastname: Chen
authors.forename: C X
authors.initials: CX
authors.lastname: Nie
authors.forename: D
authors.initials: D
authors.lastname: Liu
mesh_terms: D000818:Animals; D000947:Antigens, Helminth / Q000032:analysis*; D003429:Cross Reactions / Q000276:immunology; D007106:Immune Sera / Q000276:immunology; D015151:Immunoblotting; D010063:Ovum / Q000276:immunology; D010238:Paragonimus / Q000276:immunology*; D010446:Peptide Fragments / Q000276:immunology; D012549:Schistosoma japonicum / Q000276:immunology*
chemical_list: D000947:Antigens, Helminth; D007106:Immune Sera; D010446:Peptide Fragments