[Observation on the epidemiologic efficacy for 9 years on epidemic meningococcal polysaccharide vaccine of group A by district immunization method].
According to previous studies, there might be a peak of epidemic meningitis in Baoding City in 1984. For preventing the epidemic, we carried out vaccination with meningococcal polysaccharide vaccine by district immunization method during the 1980-1984 and then vaccination only to the children aged 12-24 months every year. The vaccination rate was 80.01% in 1980-1984 and was 97.15% in 1985-1988. During the 9 years, 833,377 children of vaccination group were observed, 4 of whom developed this disease, with an incidence of 0.48/100,000; and 304,085 children in the control group were observed, 25 of whom contracted this illness, with an incidence of 8.22/100,000. The protective rate of vaccine was 94.16% and the efficacy index was 1:17.12. This result showed that peak year of epidemic meningitis predicted in 1984 was prevented by vaccine immunization and the incidence of this disease was continuously kept less than 1/100,000 for 9 years.
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Baoding Hygiene and Epidemic Prevention Station, Hebei Province.
D000293:Adolescent; D001428:Bacterial Vaccines; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008585:Meningitis, Meningococcal / Q000453:epidemiology / Q000517:prevention & control*; D022401:Meningococcal Vaccines; D011135:Polysaccharides, Bacterial
D001428:Bacterial Vaccines; D022401:Meningococcal Vaccines; D011135:Polysaccharides, Bacterial; C043226:meningococcal group A polysaccharide