title: Fermentable simple sugars in self-administered medications as aetiologic agents in rampant caries. Case report.
abstract: Sucrose is recognized as the most cariogenic carbohydrate. However, other simple sugars may act as substrates for cariogenic micro-organisms. The clinical features of an adult patient suffering from rampant caries are described. It was considered that the predominant aetiologic factor was prolonged intake of mineral supplements which contained the disaccharide lactose. The principal caries risk factors included drug-induced xerostomia and prolonged contact time with the substrate in a retentive form. Chemical analysis of the products revealed the presence of lactose together with starch or glucose. A strategy for preventive management prior to restorative therapy based on chlorhexidine and fluoride-containing products was followed. Possible contributions of sugar-containing medications to caries risk status are discussed.
authors.affiliation: Department of Social and Preventive Dentistry, University of Queensland.
authors.forename: L J
authors.initials: LJ
authors.lastname: Walsh
authors.forename: W K
authors.initials: WK
authors.lastname: Seow
mesh_terms: D003731:Dental Caries / Q000209:etiology*; D005247:Feeding Behavior; D005260:Female; D005947:Glucose / Q000032:analysis; D006801:Humans; D007785:Lactose / Q000009:adverse effects* / Q000032:analysis; D008875:Middle Aged; D008903:Minerals / Q000008:administration & dosage* / Q000032:analysis; D014677:Pharmaceutical Vehicles / Q000009:adverse effects*; D012008:Recurrence; D012463:Saliva / Q000737:chemistry; D012651:Self Medication / Q000009:adverse effects; D013213:Starch / Q000032:analysis
chemical_list: D008903:Minerals; D014677:Pharmaceutical Vehicles; D013213:Starch; D005947:Glucose; D007785:Lactose