Malignant lymphoma of the thyroid: a report of two cases diagnosed by fine-needle aspiration.
Two cases of primary malignant lymphoma of the thyroid were diagnosed by fine-needle aspiration biopsy. In addition to morphologic evaluation performed on direct smears, immunophenotyping, flow cytometry, and molecular studies were performed on the aspirated material. These additional studies made a clear distinction between lymphoma and Hashimoto's thyroiditis, which may present a similar cytologic picture.
Detweiler
R E
RE
Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
Katz
R L
RL
Alapat
C
C
el-Naggar
A
A
Ordóñez
N
N
D001707:Biopsy, Needle; D004273:DNA, Neoplasm / Q000302:isolation & purification; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007150:Immunohistochemistry; D008223:Lymphoma / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology*
D004273:DNA, Neoplasm