Incarnal. A new antibacterial sesquiterpene from Basidiomycetes.
A new sesquiterpene, incarnal, was isolated from culture fluid of Gloeostereum incarnatum (Japanese name: Nikawaurokotake). Incarnal inhibited the growth of gram-positive bacteria at 6.25-12.5 micrograms/ml. The structure of incarnal has been determined to be (1-hydroxy-2,10,10-trimethyl)-3-methylene- tricyclo[6.3.0.0(2.6)]undec-5,7-diene-4,9-dione by X-ray diffraction and spectroscopic methods.
Takazawa
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H
Mushroom Research Institute of Japan, Okayama.
Kashino
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S
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification*; D001487:Basidiomycota / Q000032:analysis*; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D012717:Sesquiterpenes; C069838:incarnal