title: Effects of paternal and maternal undernutrition on growth of offspring in rats.
abstract: In adult males, undernutrition is associated with altered spermatogenesis. The present study was performed to evaluate the possible role of paternal undernutrition on growth and development of rat offspring and to compare those effects with undernutrition in pregnant animals. Male rats were fed 100%, 80% or 60% of their ad lib food intake for eight weeks and were then bred to untreated females. Pregnant rats were mated with untreated males and received their food allotments throughout pregnancy. Although male body weights and rate of successful matings were decreased by paternal undernutrition, offspring litter size, birth weights, and weights at 21 days were not significantly altered. By contrast, maternal undernutrition was associated with decreased maternal weight gain, lower offspring birth weights and body weights at weaning.
authors.affiliation: Department of Obstetrics and Gynecology, Wayne State University, Detroit, Michigan.
authors.forename: E L
authors.initials: EL
authors.lastname: Abel
mesh_terms: D000375:Aging / Q000502:physiology; D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development*; D001724:Birth Weight; D001835:Body Weight; D005220:Fathers; D005260:Female; D005298:Fertility; D008098:Litter Size; D009035:Mothers; D009748:Nutrition Disorders / Q000150:complications*; D011247:Pregnancy; D011248:Pregnancy Complications; D011270:Pregnancy, Animal; D051381:Rats; D011919:Rats, Inbred Strains