Immunological studies of osteoarthritis in bipedal rats.
Osteoarthritis (OA) models in bipedal rats were used to study the immune response, including the changes of IgG, antibody dependent cytotoxicity tests toward articular chondrocytes and the matrix. The results revealed significant difference between the bipedal and the quadruped rats. Immunological studies have proved that the OA model of bipedal rats is appropriate for the study of OA.
Chen
Y P
YP
Institute of Orthopaedics and Traumatology, China Academy of Traditional Chinese Medicine, Beijing.
Yang
Y
Y
Chen
B X
BX
D000818:Animals; D000921:Antibody-Producing Cells / Q000276:immunology; D002358:Cartilage, Articular / Q000276:immunology*; D003602:Cytotoxicity, Immunologic; D004195:Disease Models, Animal; D007074:Immunoglobulin G / Q000032:analysis*; D008214:Lymphocytes / Q000276:immunology; D010003:Osteoarthritis / Q000276:immunology*; D051381:Rats; D011919:Rats, Inbred Strains
D007074:Immunoglobulin G