[Effects of gossypol acetic acid on transport and development of fertilized eggs in rats].
The effects of gossypol acetic acid on the transport and development of fertilized eggs have been observed in rats. The results showed that gossypol acetic acid apparently delayed egg transport and retarded early development of the embryo in the oviduct. It is suggested that these two effects may be important causes of the antiimplantation action of gossypol.
Lei
H Q
HQ
Department of Pharmacology, Xian Medical University.
Xu
Y X
YX
D000818:Animals; D010065:Embryo Implantation, Delayed / Q000187:drug effects; D004622:Embryo, Mammalian / Q000187:drug effects; D005314:Embryonic and Fetal Development; D005260:Female; D006072:Gossypol / Q000031:analogs & derivatives* / Q000494:pharmacology; D010066:Ovum Transport / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D015053:Zygote / Q000187:drug effects* / Q000254:growth & development
D006072:Gossypol; C028178:gossypol acetic acid