Focal segmental glomerulosclerosis in a child with acute lymphoblastic leukemia.
A 13-year-old boy was found to have acute lymphoblastic leukemia 4 months after the diagnosis of nephrotic syndrome was made. Renal biopsy revealed focal segmental glomerulosclerosis (FSGS). While his leukemia remains in remission 7+ years from diagnosis, he requires chronic hemodialysis due to renal failure. The multiple immunosuppressive antileukemia agents he received did not appear to affect the progression of his renal disease.
Rajpoot
D
D
Renal Division Children's Medical Center, Brooklyn, N.Y.
Tejani
A
A
Rao
S
S
Miller
S
S
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D005923:Glomerulosclerosis, Focal Segmental / Q000209:etiology*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000188:drug therapy