title: Surgical correction of the craniofacial dysmorphology of Apert syndrome.
abstract: The authors present the objectives, timing, techniques, and results of surgery for the dysmorphology of the cranium, orbits, nose, midface, and mandible of patients with Apert syndrome based on personal experience with 14 patients and comprehensive review of the literature. The status of hypotheses generated in the early phase of craniofacial surgery is discussed. Published schedules for longitudinal treatment are examined and a preferred plan proposed.
authors.affiliation: Washington University School of Medicine, St. Louis, Missouri.
authors.forename: J L
authors.initials: JL
authors.lastname: Marsh
authors.forename: M
authors.initials: M
authors.lastname: Galic
authors.forename: M W
authors.initials: MW
authors.lastname: Vannier
mesh_terms: D000168:Acrocephalosyndactylia / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005147:Facial Bones / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011184:Postoperative Period; D011379:Prognosis; D012189:Retrospective Studies; D012886:Skull / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000601:surgery*; D013997:Time Factors; D014057:Tomography, X-Ray Computed