[Cytogenetic study of the mutagenicity of cucumarioside].
Mutagenic activity of cucumarioside displaying strong immunomodulating effect was studied. Two cytogenetic tests--mouse bone marrow micronucleus assay and the method for analysis of chromosomal aberrations--were used to evaluate mutagenic activity. Both tests demonstrated negative mutagenic effect.
Polikarpova
S I
SI
Volkova
O N
ON
Sedov
A M
AM
Stonik
V A
VA
Likhoded
V G
VG
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects; D002869:Chromosome Aberrations; D006027:Glycosides; D006697:Holothurin / Q000235:genetics*; D051379:Mice; D015162:Micronucleus Tests; D009153:Mutagens; D012616:Sea Cucumbers; D014315:Triterpenes / Q000494:pharmacology*
D006027:Glycosides; D009153:Mutagens; D014315:Triterpenes; D006697:Holothurin; C033504:cucumarioside
Tsitogeneticheskoe izuchenie mutagennosti kukumariozida.