GC/MS detection of paraffins in a case of lipoid pneumonia following occupational exposure to oil spray.
A case of lipoid pneumonia following occupational exposure to oil spray is described. Biological fluids (broncho-alveolar lavage and pleural fluid) are analyzed to determine if the compounds found in the industrial oils are present. The samples are purified using high-performance thin-layer chromatography, and after extraction, the compounds were submitted to infrared spectroscopy. Direct hexane extraction of biological fluids is also performed, followed by gas chromatography/mass spectrometry (GC/MS).
Penes
M C
MC
Laboratoire de Biochimie et Toxicologie, Hopital Edouard Herriot, Lyon, France.
Vallon
J J
JJ
Sabot
J F
JF
Vallon
C
C
D000336:Aerosols / Q000009:adverse effects*; D001706:Biopsy; D001992:Bronchoalveolar Lavage Fluid / Q000473:pathology; D002855:Chromatography, Thin Layer / Q000379:methods; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D009821:Oils / Q000633:toxicity*; D010232:Paraffin / Q000032:analysis*; D011017:Pneumonia, Lipid / Q000139:chemically induced*; D013055:Spectrophotometry, Infrared / Q000379:methods
D000336:Aerosols; D009821:Oils; D010232:Paraffin