In vitro remineralization of caries lesions treated with surface-active phosphates.
Intact human enamel was demineralized in vitro to obtain artificial caries lesions. Part of the lesions was then treated with different surface-active compounds and remineralized with a remineralizing solution. The other part of the lesions was de- and remineralized in the same way, but was not treated with a surface-active compound. The results indicate that none of the surface-active compounds do affect the remineralization of the caries lesions. Possible applications of the tested compounds in combination with fluoride, for the prevention of dental caries, are discussed.
Borggreven
J M
JM
Department of Biochemistry, University of Nijmegen, The Netherlands.
Lammers
P C
PC
Hoeks
T
T
Zwanenburg
B
B
Driessens
F C
FC
D003731:Dental Caries / Q000139:chemically induced*; D003743:Dental Enamel / Q000187:drug effects* / Q000378:metabolism; D006801:Humans; D008852:Microradiography; D008964:Molar, Third; D009943:Organophosphorus Compounds / Q000494:pharmacology*; D010710:Phosphates / Q000494:pharmacology*; D010742:Phospholipid Ethers / Q000494:pharmacology*; D013499:Surface Properties; D013501:Surface-Active Agents / Q000494:pharmacology*; D014089:Tooth Remineralization
D009943:Organophosphorus Compounds; D010710:Phosphates; D010742:Phospholipid Ethers; D013501:Surface-Active Agents; C069963:Glydip; C011479:hexadecyl phosphate; C018279:sodium phosphate