title: Intrapartum amnioinfusion for replacement of meconium-stained-amniotic-fluid to prevent meconium aspiration syndrome.
abstract: The presence of meconium-stained amniotic-fluid (MSAF) during labor in cephalic presentation is a potentially ominous sign of fetal distress and, a direct cause of meconium aspiration syndrome (MAS). The authors designed a new method of intrapartum amnioinfusion for replacement (IAR) of the MSAF with normal saline solution. A total of 177 parturients with MSAF were studied from July 1986 to January 1987. Seventy-three cases receiving IAR treatment were analysed and 104 cases treated routinely served as controls. The newborn infants receiving IAR treatment had a significantly lower incidence of neonatal asphyxia (P less than 0.001) and MAS (P less than 0.05). No neonatal death occurred in the treated group; whereas, three infants died in the controls. There was no significant difference in puerperal morbidity between these two groups. The results of this study suggest that IAR might be a hopeful and effective treatment for parturients with MSAF in reducing the incidence of MAS.
authors.affiliation: Department of Obstetrics and Gynecology, Zunyi Medical College.
authors.forename: B T
authors.initials: BT
authors.lastname: Wu
authors.forename: L J
authors.initials: LJ
authors.lastname: Sun
authors.forename: L Y
authors.initials: LY
authors.lastname: Tang
mesh_terms: D000650:Amnion; D000653:Amniotic Fluid; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007267:Injections; D008470:Meconium; D008471:Meconium Aspiration Syndrome / Q000517:prevention & control*; D011247:Pregnancy; D012965:Sodium Chloride / Q000008:administration & dosage*; D013396:Suction
chemical_list: D012965:Sodium Chloride