A clinical evaluation of various tumor markers for the diagnosis of pancreatic cancer.
Many substances that are widely used as tumor markers for detecting pancreatic cancer are discussed. Some are good indicators, but some are not. Among them, CA 19-9 and SPan-1 have higher sensitivity and specificity for diagnosis of pancreatic cancer. However, these markers are neither tumor-specific nor pancreatic-cancer-specific. Accurate understanding of the measurement of serum tumor markers makes it possible for them to be useful adjunctive tools for detecting pancreatic cancer, even in small cancers, and for monitoring patients after treatment.
Satake
K
K
First Department of Surgery, Osaka City University Medical School, Japan.
Chung
Y S
YS
Yokomatsu
H
H
Nakata
B
B
Tanaka
H
H
Sawada
T
T
Nishiwaki
H
H
Umeyama
K
K
D000951:Antigens, Neoplasm / Q000032:analysis; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis*; D006801:Humans; D010190:Pancreatic Neoplasms / Q000175:diagnosis*
D000951:Antigens, Neoplasm; D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor; C042317:DU-PAN-2 antigen, human; C059729:pancreatic associated antigen, SPan-1