[The phagocytic activity of the macrophages from mouse peritoneal exudate under the action of platinum preparations].
The influence of new antiblastic coordination compounds oxoplatinum and cycloplatam on murine peritoneal macrophage phagocytic activity was investigated in chemiluminescence test in vivo in vitro. The study has shown the stimulation of peritoneal macrophage activity by oxoplatinum and cycloplatam in vitro. In all days, except the first one, oxoplatinum and cycloplatam stimulated macrophage function of intact and especially immune mice.
Brin
E V
EV
Uteshev
B S
BS
D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D001202:Ascitic Fluid / Q000166:cytology* / Q000276:immunology; D002452:Cell Count; D002945:Cisplatin / Q000031:analogs & derivatives* / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D008163:Luminescent Measurements; D008264:Macrophages / Q000187:drug effects* / Q000276:immunology; D051379:Mice; D008810:Mice, Inbred C57BL; D009944:Organoplatinum Compounds / Q000494:pharmacology*; D010587:Phagocytosis / Q000187:drug effects* / Q000276:immunology; D013997:Time Factors
D000970:Antineoplastic Agents; D009944:Organoplatinum Compounds; C055928:cycloplatam; D002945:Cisplatin; C043804:diamminedichlorodihydroxyplatinum IV
Fagotsitarnaia aktivnost' makrofagov peritoneal'nogo ékssudata mysheĭ pri deĭstvii preparatov platiny.