title: [The immunohistochemical analysis of necropsy eyes and brain lesion in a case of intraocular and brain malignant lymphoma].
abstract: A case of intraocular and brain malignant lymphoma was presented in which histopathological and immunohistochemical analysis of the necropsy eyes and brain lesions were performed. Lymphoma cells infiltrated into both eyes and the brain. The tumor cells could be found only in the vitreous cavity, not in other ocular tissues. Lymphoma cells were morphologically better preserved in the vitreous cavity, than in the vitrectomized specimen. Applying immunoperoxidase techniques to the necropsy eyes and brain lesions, the lymphoma cells were identified a B cell type, and the diagnosis of vitreous biopsy specimen was confirmed.
authors.affiliation: Department of Ophthalmoloyg, Okayama University Medical School, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ohshima
authors.forename: N
authors.initials: N
authors.lastname: Matsuo
authors.forename: K
authors.initials: K
authors.lastname: Shirakawa
authors.forename: T
authors.initials: T
authors.lastname: Yoshino
authors.forename: T
authors.initials: T
authors.lastname: Akagi
mesh_terms: D001921:Brain / Q000378:metabolism / Q000473:pathology; D001932:Brain Neoplasms / Q000378:metabolism* / Q000473:pathology; D005123:Eye / Q000378:metabolism / Q000473:pathology; D005134:Eye Neoplasms / Q000378:metabolism* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D016393:Lymphoma, B-Cell / Q000378:metabolism* / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000378:metabolism* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D014822:Vitreous Body