Carbohydrate components of human immunodeficiency viruses type I and II.
The terminal carbohydrate residues of HIV I and II were detected by ferritin labeled lectins in electron microscopy. Different cell lines, which were infected with HIV I and II, expressed different terminal carbohydrate residues, which could also be detected on the viral envelope by electronmicroscopy. Especially N-Acetylgalactosamine residues were detected by Vicia villosa agglutinin only on Jurkat cells. This may have functional implications, since this lectin recognizes contrasuppressor T cells.
Schumacher
U
U
Anatomische Anstalt, University of Munich, FRG.
Eberle
J
J
Wolf
H
H
Welsch
U
U
Ziegler-Heitbrook
H W
HW
Gürtler
L
L
Deinhardt
F
F
D050260:Carbohydrate Metabolism; D002460:Cell Line; D005293:Ferritins; D015497:HIV-1 / Q000378:metabolism* / Q000648:ultrastructure; D015498:HIV-2 / Q000378:metabolism* / Q000648:ultrastructure; D006651:Histocytochemistry / Q000379:methods; D006801:Humans; D037102:Lectins; D008854:Microscopy, Electron; D013601:T-Lymphocytes / Q000166:cytology / Q000378:metabolism / Q000382:microbiology; D014759:Viral Envelope Proteins / Q000378:metabolism
D037102:Lectins; D014759:Viral Envelope Proteins; D005293:Ferritins