[Enzyme histochemical changes in the myocytes of the vascular wall under the influence of sex hormones].
Estradiol, progesterone and testosterone were administered three times in the female rats of Wistar strain. Myocytes were studied in the wall of the portal vena, posterior vena cava and aorta. The used histochemical methods showed distribution of dehydrogenases, which was characteristic of predominating anaerobic oxidation in cells. They increased their activity after animals were treated with testosterone and they reduced it after treatment with progesterone. Adenosin-3-phosphatase activity was increased after administration of estradiol and was reduced after treatment with progesterone. Better manifested activity of some enzymes in the longitudinal muscular layer of the portal vena in comparison with circular layer was connected with greater functional loading of this layer. It was found to a great extent similarity in dynamics of enzyme histochemical changes in arterial and venous myocytes.
Khristova
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D000818:Animals; D004958:Estradiol / Q000494:pharmacology; D005260:Female; D012739:Gonadal Steroid Hormones / Q000494:pharmacology*; D006651:Histocytochemistry; D006801:Humans; D006867:Hydrolases / Q000187:drug effects / Q000378:metabolism; D007223:Infant; D009131:Muscle, Smooth, Vascular / Q000187:drug effects* / Q000201:enzymology; D010088:Oxidoreductases / Q000187:drug effects / Q000378:metabolism; D011374:Progesterone / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D013739:Testosterone / Q000494:pharmacology
D012739:Gonadal Steroid Hormones; D013739:Testosterone; D011374:Progesterone; D004958:Estradiol; D010088:Oxidoreductases; D006867:Hydrolases
Enzimokhistokhimichni izmeneniia v miotsitite na sŭdovata stena pod vliianie na polovi khormoni.