title: Serum keratan sulphate levels rise in rheumatoid arthritis patients, but fall in ankylosing spondylitis patients compared with normal controls.
abstract: Serum levels of keratan sulphate (KS) were found to be significantly elevated in patients with destructive and predominantly seronegative rheumatoid arthritis (RA) compared with a control population. Levels in RA did not correlate with clinical or laboratory indices of joint activity or damage. Conversely levels were depressed in ankylosing spondylitis (AS) compared with controls.
authors.affiliation: Royal National Hospital for Rheumatic Diseases, Bath, U.K.
authors.forename: R
authors.initials: R
authors.lastname: Will
authors.forename: J
authors.initials: J
authors.lastname: Elswood
authors.forename: L
authors.initials: L
authors.lastname: Edmunds
authors.forename: A
authors.initials: A
authors.lastname: Calin
mesh_terms: D001172:Arthritis, Rheumatoid / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis; D006801:Humans; D007632:Keratan Sulfate / Q000097:blood*; D012016:Reference Values; D013167:Spondylitis, Ankylosing / Q000097:blood*
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein; D007632:Keratan Sulfate