title: Gynandroblastoma of the ovary having a typical morphological appearance: a case study.
abstract: A rare gynandroblastoma of the right ovary with a typical morphological appearance in a 65-year-old woman is reported. The tumor comprised both a granulosa cell element with a Call-Exner body and a Sertoli cell element. Pathologically, this case could be the most typical of all the world's established cases. Clinically, there were feminizing symptoms such as post-menopausal genital bleeding and endometrial cystic hyperplasia. Pre-operative serum hormonal assays indicated elevated levels of estrone, estradiol and testosterone, and low levels of gonadotropins. These returned to normal after surgery.
authors.affiliation: Department of Gynecology, National Cancer Center Hospital, Tokyo.
authors.forename: Y
authors.initials: Y
authors.lastname: Yamada
authors.forename: K
authors.initials: K
authors.lastname: Ohmi
authors.forename: R
authors.initials: R
authors.lastname: Tsunematu
authors.forename: H
authors.initials: H
authors.lastname: Yokota
authors.forename: T
authors.initials: T
authors.lastname: Yamada
authors.forename: K
authors.initials: K
authors.lastname: Tanemura
authors.forename: T
authors.initials: T
authors.lastname: Sonoda
authors.forename: K
authors.initials: K
authors.lastname: Kishi
authors.forename: S
authors.initials: S
authors.lastname: Teshima
mesh_terms: D000368:Aged; D005260:Female; D012739:Gonadal Steroid Hormones / Q000378:metabolism; D006801:Humans; D018309:Neoplasms, Gonadal Tissue / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D010051:Ovarian Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery
chemical_list: D012739:Gonadal Steroid Hormones