title: A study of so-called hypochondriasis.
abstract: Twenty-four patients with unexplained somatic complaints were subjected to a thorough somatic examination. Only when the examination proved negative was the patient entered into the study. The patients were clinically appraised according to criteria given in DSM-III. Generalized anxiety disorder (GAD) was diagnosed in 12, somatization disorder (SD) in 8, and hypochondriasis in 4 patients. Seventeen of the 24 patients agreed to participate in biochemical investigations including a TRH load, a dexamethasone test, and a determination of the monoamine metabolites 5-HIAA and HVA in cerebrospinal fluid (CSF). A normal TSH increase and a normal suppression of cortisol were registered. The HVA values correlated significantly with the 5-HIAA values as well as with the alexithymia scores. Concerning alexithymia and maturity level, no difference as to social class was found. The patients filled in a Zung depression chart. The Zung scale and the 5-HIAA values were both inconsistent with depressive illness. In so-called hypochondriasis a long-term relationship, including selected somatic and biochemical examinations and thorough information, was crucial in abating the patient's distrust and thus the need for health care.
authors.affiliation: Department of Medicine, Ostersund Hospital, Sweden.
authors.forename: C
authors.initials: C
authors.lastname: von Scheele
authors.forename: L
authors.initials: L
authors.lastname: Nordgren
authors.forename: V
authors.initials: V
authors.lastname: Kempi
authors.forename: J
authors.initials: J
authors.lastname: Hetta
authors.forename: A
authors.initials: A
authors.lastname: Hallborg
mesh_terms: D000328:Adult; D000368:Aged; D001008:Anxiety Disorders / Q000175:diagnosis / Q000523:psychology; D001143:Arousal; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006998:Hypochondriasis / Q000175:diagnosis* / Q000523:psychology; D008297:Male; D008875:Middle Aged; D012803:Sick Role; D013001:Somatoform Disorders / Q000175:diagnosis* / Q000523:psychology