[The carbohydrate metabolic characteristics of patients with diffuse toxic goiter proceeding with an increase in body weight].
Altogether 10 patients (aged 15 to 18) with Basedow's disease, accompanied by a growing body mass were investigated before operation and 5 patients 6 mos. after subtotal strumectomy. Ten patients with Basedow's diseases without body mass increment were taken as controls. A characteristic feature of carbohydrate metabolism in the study group as compared to the control group was hyperinsulinism with normal GTT which was preserved after doing away with thyrotoxicosis. The C-peptide/IRI ratio in patients with Basedow's disease, accompanied by a growing body mass, was decreased as compared to the control group, a tendency towards its increase after subtotal strumectomy was observed. Any differences in the levels of thyroid hormones, TSH and thyroid stimulating blood activity were undetectable.
Sviridenko
N Iu
NIu
Lobanova
A M
AM
Starkova
N T
NT
D000293:Adolescent; D001786:Blood Glucose / Q000032:analysis; D002096:C-Peptide / Q000097:blood; D002241:Carbohydrates / Q000097:blood*; D005951:Glucose Tolerance Test; D006111:Graves Disease / Q000097:blood* / Q000503:physiopathology; D006801:Humans; D007330:Insulin Antibodies / Q000097:blood; D007515:Islets of Langerhans / Q000503:physiopathology; D013963:Thyroid Hormones / Q000097:blood; D013972:Thyrotropin / Q000097:blood; D015430:Weight Gain / Q000502:physiology*
D001786:Blood Glucose; D002096:C-Peptide; D002241:Carbohydrates; D007330:Insulin Antibodies; D013963:Thyroid Hormones; D013972:Thyrotropin
Osobennosti uglevodnogo obmena u bol'nykh diffuznym toksicheskim zobom, protekaiushchim s narastaniem massy tela.