title: Pathological effects of pellagra on the esophagus.
abstract: This study determined the pathological effects of niacin/tryptophan deficiency on the esophagus. Nine patients with severe clinical pellagra and 31 age- and sex-matched controls were assessed. All pellagrins had an esophagitis varying from severe to mild. The esophagitis improved in five patients following six to seven days of vitamin therapy. The relationship between vitamin deficiencies and esophageal cancer is discussed.
authors.affiliation: Gastroenterology Unit, Baragwanath Hospital, Johannesburg, South Africa.
authors.forename: I
authors.initials: I
authors.lastname: Segal
authors.forename: M
authors.initials: M
authors.lastname: Hale
authors.forename: A
authors.initials: A
authors.lastname: Demetriou
authors.forename: A E
authors.initials: AE
authors.lastname: Mohamed
mesh_terms: D000328:Adult; D004032:Diet; D004938:Esophageal Neoplasms / Q000209:etiology* / Q000517:prevention & control; D004941:Esophagitis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010383:Pellagra / Q000150:complications*; D012307:Risk Factors; D013019:South Africa; D014815:Vitamins / Q000627:therapeutic use; D003313:Zea mays
chemical_list: D014815:Vitamins