[Primary bilateral, adrenal, highly malignant B-cell lymphoma with lymphoblastic mengiosis].
A 64-year-old man with high malignant B-cell lymphoma in both adrenal glands was investigated. Adrenal insufficiency was his predominant symptom at presentation. Despite surgical resection of the malignancy and cytostatic chemotherapy leptomeningeal involvement occurred and the patient died nine month after the diagnosis. Nine so far reported cases with primary adrenal lymphoma were reviewed. One of these also developed lymphomatous leptomeningitis. Suggestions of a pathogenetic contribution of adrenal lymphoma to leptomeningeal involvement and arising therapeutic consequences in the treatment of primary adrenal lymphoma are discussed.
Robertz-Vaupel
G M
GM
Medizinische Universitätsklinik Bonn.
Glasmacher
A G
AG
Vogel
J
J
Vaupel
H A
HA
Köster
O
O
Pizzulli
L
L
D000310:Adrenal Gland Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D006801:Humans; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000556:secondary*; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
Primär beidseitiges, adrenales, hochmalignes B-Zell-Lymphom mit Meningiosis lymphoblastica.