title: Effects of lithium treatment on eye movements.
abstract: Smooth pursuit eye movements (SPEMs) of 11 bipolar manic patients were impaired during lithium treatment, which, however, improved their clinical condition. SPEM impairment was evident in a general qualitative degradation of eye tracking integrity, in a tendency for gain to be lowered, and in an increase in the number of saccadic events. Individual differences in the nature and magnitude of effects of lithium on eye movements were noteworthy.
authors.affiliation: Harvard University, Department of Psychology, Cambridge, MA 02138.
authors.forename: P S
authors.initials: PS
authors.lastname: Holzman
authors.forename: C
authors.initials: C
authors.lastname: O'Brian
authors.forename: C
authors.initials: C
authors.lastname: Waternaux
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000523:psychology; D005260:Female; D006801:Humans; D008094:Lithium / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D011569:Psychiatric Status Rating Scales; D011698:Pursuit, Smooth / Q000187:drug effects*; D012438:Saccades / Q000187:drug effects*
chemical_list: D008094:Lithium