title: Necrosectomy by lavage in the surgical treatment of severe necrotizing pancreatitis. Results in 263 patients.
abstract: A conservative surgical technique for treatment of necrotizing pancreatitis is described. Standardized since 1976, the technique is based on washout mechanical necrosectomy accomplished by lavages via intraoperatively placed wide-bore drainage tubes. The overall mortality rate from necrotizing pancreatitis was thereby reduced from 61% (with resective technique) to 18%, and in 106 cases observed from the onset of the disease the mortality fell to only 6.6%. The series included also patients with fulminant acute pancreatitis and multiorgan failure.
authors.affiliation: Department of Surgery, University of Verona, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Pederzoli
authors.forename: C
authors.initials: C
authors.lastname: Bassi
authors.forename: S
authors.initials: S
authors.lastname: Vesentini
authors.forename: C
authors.initials: C
authors.lastname: Iacono
authors.forename: N
authors.initials: N
authors.lastname: Nicoli
authors.forename: G
authors.initials: G
authors.lastname: Mangiante
authors.forename: S
authors.initials: S
authors.lastname: Corrà
authors.forename: M
authors.initials: M
authors.lastname: Falconi
authors.forename: F
authors.initials: F
authors.lastname: Nifosi
authors.forename: R
authors.initials: R
authors.lastname: Girelli
mesh_terms: D000208:Acute Disease; D000328:Adult; D004322:Drainage; D005260:Female; D006801:Humans; D008297:Male; D009336:Necrosis; D010195:Pancreatitis / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D011183:Postoperative Complications; D015996:Survival Rate; D007507:Therapeutic Irrigation