title: Immunologic investigations in eight patients with incontinentia pigmenti.
abstract: We studied eight patients with incontinentia pigmenti to investigate the possibility of immunologic abnormalities. In six patients a defect of polymorphonuclear chemotaxis was revealed; lymphocyte subpopulations, serum immunoglobulin levels, and peripheral eosinophils were within normal limits. We hope these findings will stimulate further investigations into the mechanisms involved.
authors.affiliation: Institute of Dermatologic Clinic 1st, University of Milan, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Menni
authors.forename: R
authors.initials: R
authors.lastname: Piccinno
authors.forename: A
authors.initials: A
authors.lastname: Biolchini
authors.forename: A
authors.initials: A
authors.lastname: Plebani
mesh_terms: D000293:Adolescent; D002634:Chemotaxis, Leukocyte; D002648:Child; D002675:Child, Preschool; D005260:Female; D006098:Granulocytes; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007184:Incontinentia Pigmenti / Q000276:immunology* / Q000473:pathology; D016131:Lymphocyte Subsets; D008297:Male
chemical_list: D007136:Immunoglobulins