title: Plasma acid and alkaline phosphatase in patients with breast cancer.
abstract: Acid and alkaline phosphatase were determined in 107 breast cancer patients to study their potential value in case of bone metastases. The patients were divided into 4 groups: A, patients without metastases (n = 34); B, metastatic patients without bone lesions (n = 37); C, patients with metastases in and outside of bones (n = 24), D, patients with bone-only metastases (n = 12). Tartrate resistant acid phosphatase (TR-ACP), and bone alkaline phosphatase (bone-ALP) were significantly higher in patients with metastases than in patients without. However, no difference in TR-ACP was observed between subgroups of metastatic patients.
authors.affiliation: Centre Oscar Lambret, Lille, France.
authors.forename: M
authors.initials: M
authors.lastname: Nguyen
authors.forename: J
authors.initials: J
authors.lastname: Bonneterre
authors.forename: B
authors.initials: B
authors.lastname: Hecquet
authors.forename: B
authors.initials: B
authors.lastname: Desoize
authors.forename: A
authors.initials: A
authors.lastname: Demaille
mesh_terms: D000135:Acid Phosphatase / Q000097:blood*; D000469:Alkaline Phosphatase / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood*; D001859:Bone Neoplasms / Q000097:blood / Q000175:diagnosis / Q000201:enzymology / Q000556:secondary*; D001842:Bone and Bones / Q000201:enzymology; D001943:Breast Neoplasms / Q000097:blood* / Q000175:diagnosis / Q000201:enzymology; D005260:Female; D006801:Humans; D007527:Isoenzymes / Q000097:blood*; D009362:Neoplasm Metastasis
chemical_list: D014408:Biomarkers, Tumor; D007527:Isoenzymes; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase