title: [Effect of pirenzepine on gallbladder volume during eating and gallbladder emptying after eating in humans].
abstract: The effect of pirenzepine (50 mg p.o.) vs placebo on the fasted gallbladder emptying after a test meal was examined in a double-blind study on 14 healthy male volunteers by means of an ultrasonographic method. Pirenzepine inhibited significantly the meal-induced gallbladder emptying, whereas no significant effect of this drug on the fasted gallbladder volume was observed.
authors.affiliation: Katedry i Kliniki Gastroenterologii Sl. AM w Katowicach.
authors.forename: C
authors.initials: C
authors.lastname: Kucio
authors.forename: Z
authors.initials: Z
authors.lastname: Sliwiński
authors.forename: K
authors.initials: K
authors.lastname: Jonderko
authors.forename: A
authors.initials: A
authors.lastname: Nowak
mesh_terms: D000328:Adult; D004311:Double-Blind Method; D004435:Eating / Q000502:physiology*; D005704:Gallbladder / Q000000981:diagnostic imaging / Q000187:drug effects*; D006801:Humans; D008297:Male; D010890:Pirenzepine / Q000494:pharmacology*; D012016:Reference Values; D014463:Ultrasonography
chemical_list: D010890:Pirenzepine
vernacular_title: Ocena wpływu pirenzepiny na miedzyposiłkowa objetość pçherzyka zółciowego i jego opróznianie po bodźcu pokarmowym u ludzi.