title: Development of the human visual system: monocular and binocular pattern VEP latency.
abstract: Pattern visual evoked potentials (P-VEPs) were recorded in 161 human infants who were between 3 weeks and 2 yr of age. The latency of the first reproducible positive peak in the P-VEP was measured monocularly and binocularly for five sizes of phase alterations checkerboard stimuli (range: 120' to 7.5' check widths). Rapid visual maturation in the first 6 months of life was shown by the development of reproducible P-VEPs to smaller check sizes and by a rapid decrease in the latency of the first reproducible positive peak. Monocular P-VEPs have slightly longer latencies than the binocular P-VEPs. This latency difference is invariant with age, but is significantly greater with larger check stimuli. Normal ranges for this large population are provided as a reference for clinical studies.
authors.affiliation: Department of Ophthalmology, Hospital for Sick Children, Toronto, Canada.
authors.forename: D L
authors.initials: DL
authors.lastname: McCulloch
authors.forename: B
authors.initials: B
authors.lastname: Skarf
mesh_terms: D000328:Adult; D002675:Child, Preschool; D005074:Evoked Potentials, Visual / Q000502:physiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010364:Pattern Recognition, Visual / Q000502:physiology*; D015348:Vision, Binocular / Q000502:physiology*; D015349:Vision, Monocular / Q000502:physiology*; D014792:Visual Acuity / Q000502:physiology