[Evaluation of antianginal effectiveness of nicardipine in patients with angina pectoris].
The new calcium antagonist nicardipine was studied for its potency in 73 patients with coronary heart disease concurrent with angina pectoris, including 16 with vasospastic angina. Nicardipine given in a mean daily dose of 70.1 +/- 12.4 mg induced an increase in exercise test duration by 1-2 min in 71.9% of the patients as compared with placebo. The agent was slightly less potent than nifedipine. In vasospastic angina, nicardipine was effective in 81.3% of the patients.
Guliev
A B
AB
Sumarokov
A B
AB
Mironova
I Iu
IIu
Sidorenko
B A
BA
D000787:Angina Pectoris / Q000188:drug therapy*; D004562:Electrocardiography; D015716:Electrocardiography, Ambulatory; D005080:Exercise Test; D006801:Humans; D009529:Nicardipine / Q000008:administration & dosage / Q000627:therapeutic use*
D009529:Nicardipine
Otsenka antianginal'noĭ éffektivnosti nikardipina u bol'nykh so stenokardieĭ.