title: [The antiradiation activity and mechanism of action of dimethylaminodithiazines].
abstract: A new group of radioprotective agents, dimethylaminodithiazines, was discovered. The agents are effective when used in relatively small amounts and exert a radioprotective effect rapidly with both intraperitoneal and per os injections. The role of inhibition of oxidative processes and DNA biosynthesis in the mechanism of radioprotective action of dimethylaminodithiazines is discussed.
authors.forename: V G
authors.initials: VG
authors.lastname: Vladimirov
authors.forename: Iu E
authors.initials: IuE
authors.lastname: Strel'nikov
authors.forename: S V
authors.initials: SV
authors.lastname: Amosova
authors.forename: G M
authors.initials: GM
authors.lastname: Gavrilova
authors.forename: V I
authors.initials: VI
authors.lastname: Gostevskaia
authors.forename: A S
authors.initials: AS
authors.lastname: Petrov
authors.forename: L A
authors.initials: LA
authors.lastname: Sharova
mesh_terms: D000818:Animals; D004247:DNA / Q000096:biosynthesis / Q000187:drug effects / Q000528:radiation effects; D005720:Gamma Rays; D008297:Male; D051379:Mice; D010084:Oxidation-Reduction / Q000187:drug effects / Q000528:radiation effects; D011836:Radiation Tolerance / Q000187:drug effects; D011837:Radiation-Protective Agents / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D013843:Thiazines / Q000494:pharmacology*; D013890:Thiourea / Q000031:analogs & derivatives* / Q000494:pharmacology; D013997:Time Factors
chemical_list: D011837:Radiation-Protective Agents; D013843:Thiazines; D004247:DNA; D013890:Thiourea
vernacular_title: Issledovanie protivoluchevoĭ aktivnosti i mekhanizm deĭstviia dimetilaminoditiazinov.