title: Parenteral iron dextran therapy.
abstract: Parenteral iron therapy is indicated in patients with iron-deficiency anemia associated with conditions that interfere with the ingestion or absorption of oral iron. Replacement doses of iron required to replenish iron stores are based on body weight and the observed hemoglobin value. Methods of administering iron dextran are reviewed, including intramuscular and intravenous injections of the undiluted drug, intravenous infusion of a diluted preparation, and as an addition to parenteral nutrition solutions. The overall incidence of adverse reactions associated with the parenteral administration of iron is low, but the potential for an anaphylactic reaction requires that an initial test dose be given followed by careful patient observation.
authors.affiliation: Department of Pharmacy, Christ Hospital and Medical Center, Oak Lawn, IL 60453.
authors.forename: V J
authors.initials: VJ
authors.lastname: Kumpf
authors.forename: E G
authors.initials: EG
authors.lastname: Holland
mesh_terms: D006801:Humans; D007273:Injections, Intramuscular; D007275:Injections, Intravenous; D007505:Iron-Dextran Complex / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D010289:Parenteral Nutrition, Total
chemical_list: D007505:Iron-Dextran Complex