[Mechanism of action and applications for glucose analogs].
The paper presents recent problems of the mechanism of the action of glucose analogs (especially 2-deoxy-D-glucose and 5-thio-D-glucose) at the cellular level as well as their application in experimental and clinical medicine. It has been discussed, whether 2-DG and 5-TG could be assumed to represent nonmetabolizable antimetabolites of glucose.
Torlińska
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Katedra i Zakład Fizjologii Akademii Medycznej w Poznaniu.
D000818:Animals; D000963:Antimetabolites / Q000494:pharmacology; D003847:Deoxyglucose / Q000493:pharmacokinetics / Q000494:pharmacology; D005947:Glucose / Q000031:analogs & derivatives* / Q000493:pharmacokinetics / Q000494:pharmacology*; D006801:Humans
D000963:Antimetabolites; C003002:5-thio-D-glucose; D003847:Deoxyglucose; D005947:Glucose
Mechanizm działania i zastosowanie analogów glukozy.