Ramoplanin: a review of its discovery and its chemistry.
Ramoplanin is a novel antibacterial agent with characteristics that make it suitable for development as a topical treatment for acne, infected wounds, and for treatment of antibiotic-associated diarrhoea. In this paper, the authors will review the discovery process and the descriptive chemistry of this novel molecular entity.
Parenti
F
F
Merrell Dow Research Institute-Lepetit Center, Gerenzano (VA), Italy.
Ciabatti
R
R
Cavalleri
B
B
Kettenring
J
J
D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D047630:Depsipeptides; D006020:Glycopeptides / Q000737:chemistry / Q000494:pharmacology; D010456:Peptides, Cyclic
D000900:Anti-Bacterial Agents; D047630:Depsipeptides; D006020:Glycopeptides; D010456:Peptides, Cyclic; C041438:ramoplanin