title: Comparison of different ovarian stimulation protocols for gamete intrafallopian transfer in patients with minimal and mild endometriosis.
abstract: Three different stimulation protocols were tested in patients affected by stage I and II endometriosis with no other causes of infertility, and scheduled for the gamete intrafallopian transfer technique. In two protocols a gonadotropin hormone-releasing hormone analog was used. The analog was started 6 months before stimulation in the former and along with the exogenous gonadotropin in the latter. Patients receiving only gonadotropin served as controls. Sixty patients were selected for this study; 55 reached laparoscopy. Whereas patients receiving either gonadotropin alone or simultaneous analog and gonadotropin had similar pregnancy rates, this was much higher in the patients undergoing a prolonged, medically induced hypoestrogenism. Prolonged analog pretreatment before ovarian stimulation may give better chances of success in endometriosis patients undergoing assisted reproduction techniques.
authors.affiliation: Department of Obstetrics and Gynecology, University of Genoa, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Remorgida
authors.forename: P
authors.initials: P
authors.lastname: Anserini
authors.forename: S
authors.initials: S
authors.lastname: Croce
authors.forename: M
authors.initials: M
authors.lastname: Costa
authors.forename: A
authors.initials: A
authors.lastname: Ferraiolo
authors.forename: G L
authors.initials: GL
authors.lastname: Capitanio
mesh_terms: D000328:Adult; D002064:Buserelin / Q000494:pharmacology*; D006063:Chorionic Gonadotropin / Q000494:pharmacology; D004715:Endometriosis / Q000188:drug therapy*; D004958:Estradiol / Q000097:blood; D005260:Female; D015181:Gamete Intrafallopian Transfer / Q000379:methods*; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D010062:Ovulation Induction / Q000379:methods*; D011446:Prospective Studies; D014594:Uterine Neoplasms / Q000188:drug therapy*
chemical_list: D006063:Chorionic Gonadotropin; D004958:Estradiol; D002064:Buserelin