Listeria monocytogenes endophthalmitis in a renal-transplant patient receiving ciclosporin.
Endophthalmitis due to Listeria monocytogenes developed suddenly in a 52-year-old man receiving immunosuppressive therapy for a renal transplantation carried out 2 months previously. The treatment combined low doses of ciclosporin and prednisone. The initial clinical picture was of acute hypertensive uveitis with hypopyon. Despite prompt paracentesis and appropriate antibiotic therapy, the long-term course was unfavorable, and enucleation became necessary. The occurrence of listeriosis is classic in renal-transplant recipients, but no ocular form has been reported hitherto.
Algan
M
M
Service d'Ophthalmologie B, CHR de Nancy, France.
Jonon
B
B
George
J L
JL
Lion
C
C
Kessler
M
M
Burdin
J C
JC
D001082:Aqueous Humor / Q000382:microbiology; D003524:Cyclosporins / Q000009:adverse effects* / Q000627:therapeutic use; D009877:Endophthalmitis / Q000209:etiology*; D015353:Eye Enucleation; D015818:Eye Infections, Bacterial / Q000209:etiology*; D006084:Graft Rejection; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D016030:Kidney Transplantation / Q000009:adverse effects*; D008089:Listeria monocytogenes / Q000302:isolation & purification; D008088:Listeriosis / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000009:adverse effects / Q000627:therapeutic use; D014792:Visual Acuity
D003524:Cyclosporins; D011241:Prednisone