title: A new infant oscillatory ventilator.
abstract: A new, simple and inexpensive oscillatory ventilator is described in which a rotating jet mounted in the breathing duct generates cyclically positive and negative pressures in the airway with a sinusoidal flow waveform. Unlike conventional oscillatory ventilators it is free from restrictions to inspiratory or expiratory gas flows and open to atmosphere at all times, making it intrinsically a safe system for ventilation. A prototype rotating jet oscillatory ventilator designed for application in infants was evaluated in rabbits (mean weight 3.8 kg). The positive peak and mean airway pressures were significantly less during oscillatory ventilation at 300 and 420 b.p.m. compared with normal and high frequency positive pressure ventilation at 30 and 300 b.p.m., respectively, while maintaining blood-gas tensions within the normal range. An increase in the oscillatory frequency from 300 to 420 b.p.m. provided no further benefit in terms of airway pressure, tidal volume or blood-gas tensions.
authors.affiliation: Department of Anaesthetics, Royal Postgraduate Medical School, Hammersmith Hospital, London.
authors.forename: M K
authors.initials: MK
authors.lastname: Chakrabarti
authors.forename: A
authors.initials: A
authors.lastname: Holdcroft
authors.forename: S
authors.initials: S
authors.lastname: Sapsed-Byrne
authors.forename: J G
authors.initials: JG
authors.lastname: Whitwam
mesh_terms: D000818:Animals; D002245:Carbon Dioxide / Q000097:blood; D004867:Equipment Design; D005069:Evaluation Studies as Topic; D006612:High-Frequency Ventilation; D006801:Humans; D007223:Infant; D007385:Intermittent Positive-Pressure Ventilation; D010100:Oxygen / Q000097:blood; D011817:Rabbits; D015656:Respiratory Mechanics / Q000502:physiology; D012122:Ventilators, Mechanical
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen