Pheromone response in yeast.
In response to peptide pheromones, yeast cells prepare themselves for mating; changes include arrest of the cell cycle and induction of transcription. Proteins involved in this signal transduction pathway include the pheromone receptors, subunits of a G protein, protein kinases and DNA-binding proteins. Understanding of this pathway has been facilitated by yeast genetics, which has allowed the genes encoding all of these proteins to be identified and characterized.
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Department of Microbiology, State University of New York, Stony Brook 11794.
D002453:Cell Cycle / Q000502:physiology; D002628:Chemoreceptor Cells / Q000378:metabolism; D019204:GTP-Binding Proteins / Q000378:metabolism; D005800:Genes, Fungal; D010675:Pheromones / Q000235:genetics / Q000378:metabolism*; D011956:Receptors, Cell Surface; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology; D014158:Transcription, Genetic
D010675:Pheromones; D011956:Receptors, Cell Surface; D019204:GTP-Binding Proteins