title: Membrane specific carbonic anhydrase (CAIV) expression in human tissues.
abstract: Membrane-bound carbonic anhydrase IV (CAIV) expression has been evaluated in a range of fetal and adult human tissues and in cell culture. All tissues tested showed expression of CAIV, assessed by Western blotting, with a single immunodetected band at 55 kDa. The levels varied in fetal lung and liver during development and in various zones of the fetal brain. CAIV was clearly expressed in lung, pancreatic tumour and skin cell cultures.
authors.affiliation: Department of Child Health, St George's Hospital Medical School, London, U.K.
authors.forename: N D
authors.initials: ND
authors.lastname: Carter
authors.forename: A
authors.initials: A
authors.lastname: Fryer
authors.forename: A G
authors.initials: AG
authors.lastname: Grant
authors.forename: R
authors.initials: R
authors.lastname: Hume
authors.forename: R G
authors.initials: RG
authors.lastname: Strange
authors.forename: P J
authors.initials: PJ
authors.lastname: Wistrand
mesh_terms: D015153:Blotting, Western; D001921:Brain / Q000196:embryology / Q000201:enzymology; D002256:Carbonic Anhydrases / Q000378:metabolism*; D003106:Colon / Q000201:enzymology; D006801:Humans; D007668:Kidney / Q000201:enzymology; D008099:Liver / Q000196:embryology / Q000201:enzymology; D008168:Lung / Q000196:embryology / Q000201:enzymology; D010179:Pancreas / Q000201:enzymology; D010190:Pancreatic Neoplasms / Q000201:enzymology; D014018:Tissue Distribution; D014407:Tumor Cells, Cultured
chemical_list: D002256:Carbonic Anhydrases