[Skin spots, skin nodules, gangrene of the toes].
A 42-year-old man with multiple cutaneous neurofibromacules, café-au-lait and gangrene of toes was diagnosed having neurofibromatosis in 1976. An aortography performed because of severe hypertension had shown a coarctation and bilateral renal artery stenosis in 1982. Conservative antihypertensive therapy with an ACE-inhibitor, a vasodilatating agent and a diuretic resulted in gradual normalisation of blood pressure values. A recent follow-up revealed minimal progression of neurofibromatosis and hypertensive lesions documenting a benign course for over 13 years.
Mengden
T
T
Departement für Innere Medizin, Universitätsspital Zürich.
Marincek
B
B
Zynamon
A
A
Vetter
W
W
D000328:Adult; D001017:Aortic Coarctation / Q000150:complications / Q000000981:diagnostic imaging; D001027:Aortography; D005734:Gangrene; D006801:Humans; D006978:Hypertension, Renovascular / Q000209:etiology*; D008297:Male; D009456:Neurofibromatosis 1 / Q000150:complications*; D012078:Renal Artery Obstruction / Q000150:complications / Q000000981:diagnostic imaging; D014034:Toes / Q000473:pathology
Hautflecken, Hautknoten, Zehengangrän.