title: Leukoencephalopathy in cerebral amyloid angiopathy: MR imaging in four cases.
abstract: We report four cases of biopsy proved cerebral amyloid angiopathy demonstrated by MR imaging. White matter signal hyperintensities on T2-weighted spin-echo pulse sequences were present in three patients. We believe the white matter lesions associated with cerebral amyloid angiopathy are not specific to this disorder but rather reflect hypoperfusion of distal white matter resulting from vascular disease.
authors.affiliation: Department of Radiology, University of Iowa Hospitals and Clinics, Iowa City 52242.
authors.forename: D J
authors.initials: DJ
authors.lastname: Loes
authors.forename: J
authors.initials: J
authors.lastname: Biller
authors.forename: W T
authors.initials: WT
authors.lastname: Yuh
authors.forename: M N
authors.initials: MN
authors.lastname: Hart
authors.forename: J C
authors.initials: JC
authors.lastname: Godersky
authors.forename: H P
authors.initials: HP
authors.lastname: Adams
authors.forename: S P
authors.initials: SP
authors.lastname: Keefauver
authors.forename: D
authors.initials: D
authors.lastname: Tranel
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000175:diagnosis*; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology*; D002561:Cerebrovascular Disorders / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007968:Leukoencephalopathy, Progressive Multifocal / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed