Neuropsychological and psychiatric changes following treatment of ARC patients with zidovudine.
Six homosexual men with a diagnosis of acquired immunodeficiency syndrome (AIDS)-related complex (ARC- CDC IVA/C2) were assessed with a series of neuropsychological and psychiatric tests prior to commencing treatment with zidovudine and again after 5-6 months. Significant improvements were seen in cognitive functioning, mental state and physical health at the second assessment.
Riccio
M
M
Charing Cross and Westminster Medical School, London, UK.
Burgess
A
A
Hawkins
D
D
Wilson
B
B
Thompson
C
C
D000386:AIDS-Related Complex / Q000150:complications / Q000188:drug therapy*; D000328:Adult; D003072:Cognition Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D006304:Health Status; D006716:Homosexuality; D006801:Humans; D008297:Male; D019964:Mood Disorders / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D015215:Zidovudine / Q000494:pharmacology / Q000627:therapeutic use*
D015215:Zidovudine