title: Topically applied levobunolol does not cause changes in the corneal endothelium.
abstract: The corneal endothelium was examined in ten patients suffering from ocular hypertension before, during and after four months of topical levobunolol treatment. The untreated fellow eye served as a control. The number of endothelial cells, determined with a McIntyre eyepiece and an Eisner's contact lens, was not affected by levobunolol therapy. In addition, the morphology of the cell did not appear to be affected by the drug.
authors.affiliation: 2nd Medicine School Naples, 2nd Eye Clinic Prof. Mario D'Esposito, Napoli, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Fusco
authors.forename: A
authors.initials: A
authors.lastname: Del Prete
authors.forename: A
authors.initials: A
authors.lastname: Gravina
authors.forename: G
authors.initials: G
authors.lastname: Nieto
mesh_terms: D000287:Administration, Topical; D000368:Aged; D004728:Endothelium, Corneal / Q000187:drug effects* / Q000473:pathology; D005260:Female; D006801:Humans; D002040:Levobunolol / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D009798:Ocular Hypertension / Q000188:drug therapy* / Q000473:pathology
chemical_list: D002040:Levobunolol