Lignified materials as potential medicinal resources. II. Prevention of pathogenic bacterial infections in mice.
Antibacterial activity was demonstrated when ddY mice were intraperitoneally infected with E. coli or P. aeruginosa two days after a single ip-injection of a hot-water or alkaline extract obtained from lignified materials, such as chips of slash pine, Douglas fir, tallow wood, and two shelf fungi. Lignified material is a promising medicinal resource for the prevention and/or treatment of pathogenic microbial infection.
Oh-Hara
T
T
Faculty of Pharmaceutical Sciences, Nagoya City University, Japan.
Sakagami
H
H
Kawazoe
Y
Y
Momoi
T
T
Kaiya
T
T
Kohda
K
K
Komatsu
N
N
Ohsawa
N
N
Fujimaki
M
M
Konno
K
K
D000818:Animals; D001424:Bacterial Infections / Q000517:prevention & control*; D004927:Escherichia coli Infections / Q000517:prevention & control; D008031:Lignin; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D010936:Plant Extracts / Q000627:therapeutic use*; D011552:Pseudomonas Infections / Q000517:prevention & control; D014197:Trees
D010936:Plant Extracts; D008031:Lignin