title: Incidence of common pyocin types of Pseudomonas aeruginosa from patients with cystic fibrosis and chronic airways diseases.
abstract: We sought evidence to determine if particular strains of Pseudomonas aeruginosa have a predilection for pulmonary colonisation in patients with cystic fibrosis (CF). The incidence of common pyocin types in non-CF isolates (74%) was similar to that noted in previous reports but differed significantly (X2 = 16.7, p less than 0.001) from the incidence of 40% observed in CF isolates. A retrospective analysis of respiratory isolates also indicated a relatively low incidence of common pyocin types (44%) in isolates from non-CF patients with chronic airways diseases and this incidence also differed significantly from that observed (73%) in other respiratory isolates from patients in the same hospital. These observations suggest that a subpopulation of P. aeruginosa exists which has a predilection for pulmonary colonisation in CF and other chronic pulmonary diseases and may assist in identification of factors affecting bacterial colonisation.
authors.affiliation: Department of Bacteriology, University of Edinburgh Medical School.
authors.forename: M W
authors.initials: MW
authors.lastname: Tredgett
authors.forename: C
authors.initials: C
authors.lastname: Doherty
authors.forename: J R
authors.initials: JR
authors.lastname: Govan
mesh_terms: D001430:Bacteriocins / Q000145:classification*; D003550:Cystic Fibrosis / Q000150:complications / Q000382:microbiology*; D006801:Humans; D015994:Incidence; D008173:Lung Diseases, Obstructive / Q000150:complications / Q000382:microbiology*; D011552:Pseudomonas Infections / Q000150:complications; D011550:Pseudomonas aeruginosa / Q000145:classification*; D011709:Pyocins / Q000145:classification*; D013183:Sputum / Q000382:microbiology
chemical_list: D001430:Bacteriocins; D011709:Pyocins