Resumption of gonadotrophin release during the post-partum period in suckling and non-suckling ewes.
The post-partum secretion of LH, FSH and prolactin was monitored in 15 suckling and 6 non-suckling Préalpes du Sud ewes lambing during the breeding season by measuring plasma hormone concentrations daily at 6-h intervals and also weekly at 20-min intervals for 6 h from parturition to resumption of regular cyclic ovarian activity. There was a constant phenomenon in the resumption of normal patterns of FSH and LH secretion: there was a rise in FSH values culminating on average on Day 4 post partum and returning subsequently to values observed during the oestrous cycle, and concurrently an increase in the frequency and amplitude of LH pulses more progressive in suckling than in non-suckling ewes which led to an elevation of LH mean concentrations and occurrence of an LH surge. Since neither the FSH secretory pattern nor FSH mean values differed between suckling and non-suckling ewes, the results suggested that LH pulsatile pattern was a major limiting factor for the resumption of normal oestrous cycles. Before regular oestrous cycles resumed other changes in preovulatory LH surges also occurred: (i) they increased in duration and probably in amplitude; (ii) they were preceded by an acceleration in LH pulse frequency and a large decrease in FSH values as in normal cyclic ewes; and (iii) at least in non-suckling ewes they occurred concurrently with a prolactin surge.
Schirar
A
A
Laboratoire de Neurobiologie de la Reproduction, INRA, Jouy-en-Josas, France.
Cognié
Y
Y
Louault
F
F
Poulin
N
N
Meusnier
C
C
Levasseur
M C
MC
Martinet
J
J
D000818:Animals; D004971:Estrus / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006065:Gonadotropins, Pituitary / Q000097:blood*; D007774:Lactation / Q000097:blood*; D007986:Luteinizing Hormone / Q000097:blood; D049590:Postpartum Period / Q000097:blood*; D011247:Pregnancy; D011388:Prolactin / Q000097:blood; D012756:Sheep / Q000097:blood*
D006065:Gonadotropins, Pituitary; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone