title: [Comparative study of norplant-2 and levonorgestrel-releasing intrauterine devices].
abstract: Norplant-2 and Levonorgestrel-releasing IUD were studied in a randomized comparative trial for one year. Each group consisted of 100 healthy women among whom contraceptive efficacy and acceptability were studied. Only one woman with the LNG-IUD got pregnancy during the 12 months of use. Expulsion rate was 3.0 in the LNG-IUD. Removal rate for menstrual problems was 3.0 for both groups. The use-related discontinuation were 4.0 and 10.0 respectively. Irregular bleeding was the major side-effect with the two devices. Menstrual blood loss (MBL) and haemoglobin concentration were measured in thirty women at pre- and post-insertion periods. After the 1st, 6th, 12th month of use in Norplant-2 group, the mean MBL were all less than that of pre-insertion, but the differences were not significant. Among LNG-IUD users, the MBL decreased significantly after one year of use. Haemogloblin concentrations were slightly increased in both groups.
authors.affiliation: National Research Institute for Family Planning, Beijing.
authors.forename: S L
authors.initials: SL
authors.lastname: Wang
mesh_terms: D000328:Adult; D003271:Contraceptive Agents, Female / Q000493:pharmacokinetics; D005260:Female; D006801:Humans; D007436:Intrauterine Devices, Medicated; D016912:Levonorgestrel; D009644:Norgestrel / Q000493:pharmacokinetics
chemical_list: D003271:Contraceptive Agents, Female; D009644:Norgestrel; D016912:Levonorgestrel