[The effect of immune antibodies and the xanthine oxidase-xanthine enzymatic link on Vibrio cholerae].
As revealed in experiments on V. cholerae, highly diluted cholera antiserum enhanced the inhibitory action of the enzymatic link xanthine oxidase-xanthine-Fe2+ on the multiplication of V. cholerae, while low dilutions of the antiserum weakened this action. Normal rabbit serum produced no such effect. The antivibrionic effectiveness of the immune molecular cycle, viz. antiserum--the xanthine oxidase enzymatic link, was found to depend also on the concentration of xanthine. Immune antibodies to cholera antigens activated the bacteriostatic action of the enzymatic link at the concentration of xanthine oxidase equal to 0.0125 g/l and its bactericidal action at the concentration of xanthine oxidase equal to 0.025 g/l. In this article the values of the specificity indices of immune interaction and immunological effectiveness, characterizing the effectiveness of immune molecular cycles (antibodies--the xanthine oxidase enzymatic link), are presented.
Adamov
A K
AK
Pavlova
Iu P
IuP
D000818:Animals; D000907:Antibodies, Bacterial / Q000276:immunology*; D000937:Antigen-Antibody Reactions / Q000276:immunology; D004306:Dose-Response Relationship, Immunologic; D007106:Immune Sera / Q000276:immunology; D007114:Immunization; D066298:In Vitro Techniques; D011817:Rabbits; D014734:Vibrio cholerae / Q000276:immunology*; D019820:Xanthine; D014969:Xanthine Oxidase / Q000276:immunology*; D014970:Xanthines / Q000276:immunology*
D000907:Antibodies, Bacterial; D007106:Immune Sera; D014970:Xanthines; D019820:Xanthine; D014969:Xanthine Oxidase
Vliianie immunnykh antitel i fermentnogo zvena ksantinoksidazy--ksantin na Vibrio cholerae.