Characterization of alpha and beta crystalline forms of nicardipine hydrochloride.
The aim of this work was the characterization of alpha and beta crystalline forms of nicardipine hydrochloride (coronary vasodilator drug) by means of DSC analysis, X-ray diffraction patterns, TLC analysis and IR spectroscopy. The results obtained show that it is possible to distinguish the two forms by means of these techniques.
Yan
J X
JX
Dept. of Pharmaceutical Chemistry, University of Pavia, Italy.
Giunchedi
P
P
D002855:Chromatography, Thin Layer; D003460:Crystallization; D009529:Nicardipine / Q000737:chemistry*; D012995:Solubility; D013055:Spectrophotometry, Infrared; D014961:X-Ray Diffraction
D009529:Nicardipine