Enzymatic synthesis of actinomycin D and analogues containing N-methylalanine from synthetic pentapeptide lactone precursors.
Katz
E
E
Department of Microbiology, Georgetown University, Schools of Medicine and Dentistry, Washington, D.C. 20007.
Lloyd
H A
HA
Mauger
A B
AB
D001412:Bacillus subtilis / Q000187:drug effects; D055598:Chemical Phenomena; D002621:Chemistry; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D003609:Dactinomycin / Q000031:analogs & derivatives / Q000096:biosynthesis* / Q000494:pharmacology; D007783:Lactones / Q000378:metabolism; D013211:Staphylococcus aureus / Q000187:drug effects; D013302:Streptomyces / Q000378:metabolism*; D013303:Streptomyces antibioticus / Q000201:enzymology / Q000378:metabolism*
D007783:Lactones; D003609:Dactinomycin