Microdissection and microcloning of human banded chromosomes.
A new microdissection and microcloning procedure of human banded chromosomes has been recently described. These microtechniques allow the construction of band-specific DNA libraries, providing a large number of DNA probes for the identification of gene sequences. These methodologies are particularly efficient to reach chromosomal regions involved in human genetic diseases including cancer.
Jonveaux
P
P
INSERM U301, Institut de Génétique Moléculaire, Paris, France.
Berger
R
R
D002871:Chromosome Banding; D002877:Chromosomes, Human / Q000648:ultrastructure*; D003001:Cloning, Molecular; D003582:Cytogenetics / Q000379:methods*; D004247:DNA / Q000032:analysis; D015723:Gene Library; D006801:Humans
D004247:DNA