A case of the unstable Hb Genova (beta 28 Leu----Pro) in an Arab child associated with severe haemolytic anaemia and growth retardation.
The first case of unstable Hb Genova from North Africa is described. It was found in a 13-year-old girl from Libya suffering from chronic Heinz body haemolytic anaemia and growth retardation. The available data strongly suggest that this case represents a new example for a spontaneous mutation.
Hopmeier
P
P
Central Laboratory, Municipal Hospital Lainz, Vienna, Austria.
Binder
C
C
Gadner
H
H
Fischer
M
M
D000293:Adolescent; D000745:Anemia, Hemolytic, Congenital / Q000097:blood* / Q000208:ethnology / Q000235:genetics; D001317:Austria; D002908:Chronic Disease; D005260:Female; D006130:Growth Disorders / Q000097:blood* / Q000208:ethnology / Q000235:genetics; D006366:Heinz Bodies; D006455:Hemoglobins, Abnormal / Q000032:analysis*; D006801:Humans; D008002:Libya / Q000208:ethnology
D006455:Hemoglobins, Abnormal; C029606:hemoglobin Genova