Evolutionary specificity of hydrins, new hydroosmotic neuropeptides: occurrence of hydrin 2 (vasotocinyl-Gly) in the toad Bufo marinus but not in the viper Vipera aspis.
Hydrin 2 (vasotocinyl-Gly), a hydroosmotic peptide resulting from differential processing of provasotocin and recently identified in frog neurohypophysis, has been looked for in the pituitary gland of an exotic toad (Bufo marinus) and of a reptile (Vipera aspis). Hydrin 2 has been found in the amphibian but not in the reptile. This result confirms the evolutionary specificity of hydrin 2 that has been identified only in frogs and toads but not in birds and reptiles. Occurrence of hydrin 2 is explained by its regulatory function on the water permeability of the skin of anurans.
Michel
G
G
Laboratory of Biological Chemistry, University of Paris VI, France.
Rouillé
Y
Y
Chauvet
M T
MT
Chauvet
J
J
Acher
R
R
D000818:Animals; D005075:Biological Evolution; D002024:Bufo marinus; D002851:Chromatography, High Pressure Liquid; D009479:Neuropeptides / Q000032:analysis*; D010121:Oxytocin / Q000031:analogs & derivatives / Q000302:isolation & purification; D010902:Pituitary Gland / Q000032:analysis*; D012911:Snakes; D013045:Species Specificity; D014668:Vasotocin / Q000031:analogs & derivatives* / Q000032:analysis / Q000302:isolation & purification
D009479:Neuropeptides; C060258:hydrin 2; C001713:mesotocin; D010121:Oxytocin; D014668:Vasotocin