[The prognosis of the outcome and the correction of the treatment in bacterial meningitis by using immunological monitoring].
The clinico-etiological characteristics of bacterial meningitides and cellular immunity were studied over time. Measurements were made of the phagocytic index, the phagocytic number, phagocytosis completeness, E-RFC, complementary activity of blood serum (CABS), circulating immune complexes (CIC) and IgA, IgM and IgG. The low phagocytic activity of neutrophils, phagocytosis incompleteness, the high level of CIC, a considerable reduction on CABS were associated with a grave clinical course of bacterial meningitides. In fact, they served as indicators of the necessity of instituting intensive care (hemoperfusion, plasmapheresis, ultraviolet and laser blood radiation, the use of immunomodulators). The combined administration of sodium nucleinate, levamisole and hemodez provided rapid and efficient recovery of the characteristics under study.
Lutsik
B D
BD
Kit
I E
IE
Tokarev
V P
VP
D000936:Antigen-Antibody Complex / Q000097:blood; D003165:Complement System Proteins / Q000032:analysis; D004359:Drug Therapy, Combination; D006801:Humans; D008581:Meningitis / Q000188:drug therapy / Q000276:immunology*; D008585:Meningitis, Meningococcal / Q000188:drug therapy / Q000276:immunology*; D008586:Meningitis, Pneumococcal / Q000188:drug therapy / Q000276:immunology*; D015166:Monitoring, Immunologic; D010587:Phagocytosis / Q000276:immunology; D011379:Prognosis; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000276:immunology*
D000936:Antigen-Antibody Complex; D003165:Complement System Proteins
Prognozirovanie iskhodov i korrektsiia lecheniia bakterial'nykh meningitov s ispol'zovaniem immunologicheskogo monitoringa.