title: Amine-induced polymerization of aqueous HEMA/aldehyde during action as a dentin bonding agent.
abstract: Aqueous mixtures of HEMA with glutaraldehyde or propionaldehyde polymerize by addition of catalytic amounts of amines or amino acids. The maximal reaction velocity of the transformation of HEMA/glutaraldehyde with glycine was obtained at pH 0.8. Kinetic data suggested a second-order reaction between glutaraldehyde and glycine, and solubility data suggested formation of a cross-linked polymer. A relatively high bond strength between dentin and resin composite was obtained by pre-treatment of dentin with Gluma (35% HEMA, 5% glutaraldehyde in water) adjusted to pH 1.0 with hydrochloric acid. It is proposed that on application of Gluma, amino-group-containing substances in dentin react with glutaraldehyde and start the formation of a HEMA polymer. This product may be cross-linked by an alpha,beta-unsaturated glutaraldehyde aldol condensation product and may bond to dentin by aldehyde fixation to dentin proteins. Resin composite will bond to this product by copolymerization.
authors.affiliation: Department of Dental Materials & Technology, Royal Dental College, Copenhagen N, Denmark.
authors.forename: E C
authors.initials: EC
authors.lastname: Munksgaard
mesh_terms: D000179:Acrylates; D000447:Aldehydes; D000588:Amines; D000596:Amino Acids; D055598:Chemical Phenomena; D002621:Chemistry; D001840:Dental Bonding; D003738:Dental Cements; D003799:Dental Stress Analysis; D003804:Dentin; D005976:Glutaral; D006801:Humans; D008689:Methacrylates; D011109:Polymethacrylic Acids
chemical_list: D000179:Acrylates; D000447:Aldehydes; D000588:Amines; D000596:Amino Acids; D003738:Dental Cements; D008689:Methacrylates; D011109:Polymethacrylic Acids; C005044:hydroxyethyl methacrylate; C044372:Gluma; C005556:propionaldehyde; D005976:Glutaral