title: [Changes in blood viscosity and erythrocyte deformability in patients with dyslipidemia treated with binifibrate].
abstract: 31 patients afflicted with primary hyperlipidemia who did not improve after 30 days on a diet were treated with 1800 mg/day of binifibrate. We measured the total cholesterol level and triglyceridemia, as well as blood viscosity and red cell deformability at day 0, 30, 60, 90 of treatment. We found a statistically significant decrease in cholesterol and triglyceride levels as well as blood viscosity, and an increment of red cell deformability which improved the circulatory dynamisms augmentin the tissular perfusion in these patients.
authors.affiliation: Servicio de Medicina Interna, Hospital Clínico Universitario, Facultad de Medicina, Valencia.
authors.forename: M
authors.initials: M
authors.lastname: Labiós Gómez
authors.forename: M
authors.initials: M
authors.lastname: Romero Simo
authors.forename: F
authors.initials: F
authors.lastname: Gabriel Botella
authors.forename: H
authors.initials: H
authors.lastname: Martín Valles
authors.forename: M
authors.initials: M
authors.lastname: Morera Llorca
authors.forename: J
authors.initials: J
authors.lastname: Freixas Ventura
mesh_terms: D000368:Aged; D001809:Blood Viscosity / Q000187:drug effects*; D004907:Erythrocyte Deformability / Q000187:drug effects*; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009539:Nicotinic Acids / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D000960:Hypolipidemic Agents; D009539:Nicotinic Acids; C038877:binifibrate
vernacular_title: Modificaciones de la viscosidad de la sangre y deformabilidad eritrocitaria en pacientes dislipémicos tratados con binifibrato.