[Renal changes caused by pentavalent antimonial (Glucantime) hypersensitivity in American tegumentary leishmaniasis. Report of a case].
The authors report one case of leishmaniasis in a 60 year old patient who developed renal failure after treatment with Glucantime. With the interruption of these drug the patient recovered her normal renal function, and a new treatment with Amphotericin B was tried with complete cicatrization of the lesions.
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Departamento de Dermatologia, Faculdade de Medicina, USP, São Paulo, Brasil.
Belda Júnior
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Dias
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D058186:Acute Kidney Injury / Q000139:chemically induced*; D000666:Amphotericin B / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology*; D005260:Female; D006801:Humans; D007896:Leishmaniasis / Q000188:drug therapy*; D008536:Meglumine / Q000009:adverse effects*; D000077485:Meglumine Antimoniate; D008875:Middle Aged; D009942:Organometallic Compounds / Q000009:adverse effects*
D000981:Antiprotozoal Agents; D009942:Organometallic Compounds; D008536:Meglumine; D000077485:Meglumine Antimoniate; D000666:Amphotericin B
Alterações renais por hipersensibilidade ao uso de antimonial pentavalente (Glucantime) na leishmaniose tegumentar americana. Relato de um caso.