Assay of apolipoproteins A-1 and B by immunoturbidimetry: detection of individuals at risk for atherosclerotic artery disease.
Recent evidence has suggested that the levels of Apolipoprotein A-1 and B in plasma are better indicators of the risk of atherosclerotic artery disease than plasma lipids. This study describes the measurement of plasma Apolipoprotein A-1 and B by immunoturbidimetry in patients with atherosclerotic artery disease and in normal controls. Apoprotein B and the ratio of Apoprotein A-1/Apoprotein B were found to be the best discriminators between the two groups.
Sullivan
D
D
Department of Biochemistry, Mater Misericordiae Hospital, Dublin, Ireland.
Kyne
F
F
Maguire
S
S
Sugrue
D
D
Wright
E
E
Garvey
L
L
UaConaill
D
D
D000328:Adult; D000368:Aged; D001054:Apolipoproteins A / Q000032:analysis*; D001055:Apolipoproteins B / Q000032:analysis*; D003327:Coronary Disease / Q000097:blood* / Q000453:epidemiology; D005260:Female; D006801:Humans; D007118:Immunoassay / Q000592:standards; D005779:Immunodiffusion / Q000592:standards; D008074:Lipoproteins / Q000097:blood; D008297:Male; D008875:Middle Aged; D009391:Nephelometry and Turbidimetry / Q000592:standards; D011933:Reagent Kits, Diagnostic / Q000592:standards; D015203:Reproducibility of Results; D012307:Risk Factors
D001054:Apolipoproteins A; D001055:Apolipoproteins B; D008074:Lipoproteins; D011933:Reagent Kits, Diagnostic