title: [Evaluation of the relative effectiveness of hybridization probes prepared by action of hydrazides of biotin derivatives on DNA].
abstract: Efficiencies of biotinylated DNAs as hybridisation probes in a model system of non-radioactive detection were compared. Probes were obtained by interaction of single-stranded DNA and each of four different hydrazides of biotin derivatives. The most sensitivity in detection of complementary target was obtained using (biocytin hydrazide)-treated DNA. Relations between hydrazide structures and sensitivity of biotinylated probes are discussed.
authors.forename: N N
authors.initials: NN
authors.lastname: Karpyshev
authors.forename: T Iu
authors.initials: TIu
authors.lastname: Bondarenko
authors.forename: S M
authors.initials: SM
authors.lastname: Kipriianov
mesh_terms: D001710:Biotin; D055598:Chemical Phenomena; D002621:Chemistry; D015342:DNA Probes / Q000138:chemical synthesis*; D006834:Hydrazines; D009693:Nucleic Acid Hybridization
chemical_list: D015342:DNA Probes; D006834:Hydrazines; D001710:Biotin
vernacular_title: Otsenka otnositel'noĭ éffektivnosti gibridizatsionnykh zondov, poluchennykh deĭstviem gidrazidov proizvodnykh biotina na DNK.