Risks involved in large-scale freeze-drying of immunological preparations.
Types of biohazards occurring in processing vaccines with freeze-drying method are scrutinized. The attention is payed to risky transfer of infections from animals to human subjects as well as the onset of allergies and contaminations with alien substances, and as a result of impurity of preparation produced. Risks related to the use of freeze-drying are scrutinized in detail.
Sisáková
E
E
Bioveta, National Enterprise, Control Laboratory.
Polácek
R
R
D004340:Drug Contamination; D004345:Drug Industry; D004356:Drug Storage; D005612:Freeze Drying; D006801:Humans; D006967:Hypersensitivity; D007757:Laboratory Infection; D009784:Occupational Diseases; D014612:Vaccines / Q000009:adverse effects / Q000276:immunology
D014612:Vaccines