title: Factor VIII:C relationships to selected lipids, age, and gender in healthy adults.
abstract: The relationships between cholesterol, high-density lipoprotein-cholesterol (HDL-C), age, gender, estrogen use, and coagulation factor VIII (VIII:C) were examined in a group (n = 230) of healthy adults, age 21 to 68. No relationships were noted between factor VIII:C and cholesterol or estrogen usage; Factor VIII:C and age were positively related. A significant negative correlation was found between factor VIII:C and HDL-C in the group after the adjustment of age and gender. The study suggests possible relationship of VIII:C to development of arterial disease during the aging process.
authors.affiliation: Department of Health Sciences, Illinois State University, Normal 61761.
authors.forename: M J
authors.initials: MJ
authors.lastname: Corsaut
authors.forename: T J
authors.initials: TJ
authors.lastname: Bierma
authors.forename: R M
authors.initials: RM
authors.lastname: Kasa
mesh_terms: D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood*; D005169:Factor VIII / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D012016:Reference Values; D012044:Regression Analysis; D012737:Sex Factors
chemical_list: D008076:Cholesterol, HDL; D005169:Factor VIII; D002784:Cholesterol