Acute renal allograft rejection: the role of monoclonal antibodies in treatment: experience with orthoclonal anti-T3 cell antibody.
We have reviewed the literature relating to the use of monoclonal antibodies in acute renal allograft rejection. More emphasis has been placed on Orthoclone OKT3 which has been more commonly used and summarise our experience with its use as rescue therapy in renal allograft rejection.
McLigeyo
S O
SO
Transplant Unit, Western General Hospital, Edinburgh.
Notghi
A
A
Anderton
J L
JL
Dick
J
J
D000208:Acute Disease; D000911:Antibodies, Monoclonal / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D004341:Drug Evaluation; D005260:Female; D006084:Graft Rejection / Q000187:drug effects*; D006801:Humans; D007165:Immunosuppression Therapy; D016030:Kidney Transplantation; D008297:Male; D016853:Muromonab-CD3
D000911:Antibodies, Monoclonal; D016853:Muromonab-CD3