Donor pretreatment with IFN-gamma enhances MHC class II antigen expression and accelerates graft rejection by modified recipients.
Ijzermans
J N
JN
Department of Surgery, Erasmus University Rotterdam, The Netherlands.
Bouwman
E
E
Jeekel
J
J
Marquet
R L
RL
D000818:Animals; D003524:Cyclosporins / Q000627:therapeutic use; D005802:Genes, MHC Class II / Q000187:drug effects*; D006084:Graft Rejection / Q000187:drug effects*; D000949:Histocompatibility Antigens Class II / Q000032:analysis; D007124:Immunoenzyme Techniques; D007165:Immunosuppression Therapy; D007371:Interferon-gamma / Q000494:pharmacology*; D008297:Male; D051381:Rats; D011917:Rats, Inbred Lew; D011919:Rats, Inbred Strains; D011994:Recombinant Proteins; D016038:Skin Transplantation / Q000276:immunology*
D003524:Cyclosporins; D000949:Histocompatibility Antigens Class II; D011994:Recombinant Proteins; D007371:Interferon-gamma