title: [Experimental evaluation of the role of the coronary sinus pressure in the regulation of coronary return volume via the coronary sinus. Surgical considerations in atrio-pulmonary diversion procedures].
abstract: In order to find out the validity of the vascular waterfall mechanism in coronary venous circulation, the role of coronary sinus pressure in the regulation of coronary return volume via the coronary sinus is studied in healthy animals. An experimental model of pressure regulation in the coronary sinus was prepared, and aortic pressure, EKG and the cardiac output (measured by thermodilution) were recorded. The return volume via the coronary sinus was measured at coronary sinus pressure of 10 or less, 15, 20, and 25 mmHg or more, for a total of 36 determinations. Increased coronary sinus pressure did not produce significant changes in aortic pressure, heart rate, cardiac index or coronary return volume via coronary sinus. When coronary sinus pressure was 25 mmHg or more, there was a significant decline in the average of coronary return volume via coronary sinus. Nevertheless, stepwise variant regression showed that the coronary sinus pressure per se does not condition the volume of coronary return via the coronary sinus. Our results suggest that in the healthy animals, the vascular waterfall mechanism in coronary venous circulation is not valid. Our results suggest that in the correction of congenital cardiac malformations using atriopulmonary anastomosis procedures, employing techniques that ensure coronary sinus drainage into the left atrium, in order to avoid the hemodynamic repercussions attributable to the vascular waterfall mechanism, is not justified.
authors.affiliation: Servicio de Cirugía Experimental, Hospital La Paz, Madrid.
authors.forename: P
authors.initials: P
authors.lastname: Fantidis
authors.forename: M A
authors.initials: MA
authors.lastname: Fernández Ruiz
authors.forename: R
authors.initials: R
authors.lastname: Madero Jarabo
authors.forename: F
authors.initials: F
authors.lastname: Moreno Granados
authors.forename: G
authors.initials: G
authors.lastname: Cordovilla Zurdo
authors.forename: E
authors.initials: E
authors.lastname: Sanz Galeote
mesh_terms: D000714:Anastomosis, Surgical; D000818:Animals; D001794:Blood Pressure / Q000502:physiology*; D006348:Cardiac Surgical Procedures / Q000379:methods*; D003326:Coronary Circulation / Q000502:physiology*; D003331:Coronary Vessels / Q000502:physiology*; D004285:Dogs; D004562:Electrocardiography; D006325:Heart Atria / Q000601:surgery*; D015999:Multivariate Analysis; D011651:Pulmonary Artery / Q000601:surgery*
vernacular_title: Valoración experimental del papel de la presión en seno coronario en la regulación del volumen de retorno vía seno coronario. Consideraciones quirúrgicas en las técnicas de derivación atriopulmonar.