title: Hepatitis delta virus superinfection in Guangzhou area.
abstract: Biopsy and autopsy specimens of liver tissues of two series of patients, one of adults and the other children suffering from hepatitis B virus (HBV) infection were used to evaluate hepatitis delta virus antigen (HDAg) by direct immunoperoxidase staining method. The results showed that four HDAg positive cases were found among 30 cases of HBV infected adult patients (13.3%), and 6 were found in 44 cases in the children series (13.6%). Therefore, we are convinced that hepatitis delta virus (HDV) superinfection does exist in Guangzhou area. The superinfection rates in adults and children are almost identical.
authors.affiliation: Department of Pathology, Guangzhou Children's Hospital.
authors.forename: G H
authors.initials: GH
authors.lastname: Chen
authors.forename: M D
authors.initials: MD
authors.lastname: Zhang
authors.forename: W
authors.initials: W
authors.lastname: Huang
mesh_terms: D000328:Adult; D000956:Antigens, Viral / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D006509:Hepatitis B / Q000276:immunology; D003699:Hepatitis D / Q000453:epidemiology* / Q000276:immunology; D003698:Hepatitis Delta Virus / Q000276:immunology*; D035923:Hepatitis delta Antigens; D006521:Hepatitis, Chronic / Q000276:immunology; D006801:Humans; D008099:Liver / Q000276:immunology; D008297:Male; D008875:Middle Aged; D015163:Superinfection / Q000453:epidemiology* / Q000276:immunology
chemical_list: D000956:Antigens, Viral; D035923:Hepatitis delta Antigens; C442244:hepatitis delta virus large antigen