The biocompatibility of compressed collagen foam plugs.
The tissue reaction to reexpanded, purified bovine collagen sponge placed percutaneously into the lung, pleural space, liver, kidney, and muscle was studied in dogs and rabbits. In addition, the biocompatibility and radiopacity of tantalum-treated collagen foam plugs was examined. No adverse effects were found. We believe that collagen plugs may be of use in occluding needle tracts from biopsy sites to prevent complications such as bleeding or pneumothoraces.
Robinson
J D
JD
Department of Diagnostic Radiology, University of Minnesota Hospital and Clinic, Minneapolis 55455.
Yedlicka
J W
JW
Bildsoe
M C
MC
Vlodaver
Z
Z
Hunter
D W
DW
Castañeda-Zúñiga
W
W
Amplatz
K
K
D000818:Animals; D001672:Biocompatible Materials; D004285:Dogs; D004621:Embolization, Therapeutic / Q000379:methods*; D005781:Gelatin Sponge, Absorbable / Q000008:administration & dosage / Q000494:pharmacology*; D007668:Kidney / Q000187:drug effects; D008099:Liver / Q000187:drug effects; D008168:Lung / Q000187:drug effects*; D009132:Muscles / Q000187:drug effects; D011817:Rabbits
D001672:Biocompatible Materials