A novel effect of adenovirus VA RNA1 on cytoplasmic mRNA abundance.
Adenovirus VA RNA1 is a small RNA polymerase III transcript that enhances mRNA translation both in transfected cells and during a lytic virus infection. Here we present evidence that VA RNA1 also, in length-dependent manner, increases cytoplasmic mRNA abundance in transient expression assays in 293 cells.
Svensson
C
C
Department of Microbial Genetics, Karolinska Institutet, Stockholm, Sweden.
Akusjärvi
G
G
D000256:Adenoviridae / Q000235:genetics*; D015500:Chloramphenicol O-Acetyltransferase / Q000096:biosynthesis / Q000235:genetics; D003593:Cytoplasm / Q000378:metabolism; D012321:DNA-Directed RNA Polymerases / Q000502:physiology*; D014176:Protein Biosynthesis; D012320:RNA Polymerase III / Q000502:physiology*; D012333:RNA, Messenger / Q000032:analysis / Q000378:metabolism*; D012367:RNA, Viral / Q000502:physiology*; D014162:Transfection; D001616:beta-Galactosidase / Q000235:genetics
D012333:RNA, Messenger; D012367:RNA, Viral; D015500:Chloramphenicol O-Acetyltransferase; D012321:DNA-Directed RNA Polymerases; D012320:RNA Polymerase III; D001616:beta-Galactosidase