[Pneumocystis carinii pneumonia in patients with HIV infection at a Spanish hospital].
Thirty cases of a first episode of Pneumocystis carinii pneumonia in patients with HIV infection were collected in a 32 month period. Most patients had long standing fever, cough and dyspnea. Laboratory findings were nonspecific. Remarkably, LDH activity was high in 88% of patients and the T4 lymphocyte count was lower than 200/mm3 in all patients in whom it was measured. Chest radiogram showed bilateral alveolar-interstitial pattern in 90% of cases. Bronchoalveolar lavage with ultracentrifugation was found to be the most effective diagnostic study, with 95% sensitivity. The frequency of secondary effects to cotrimoxazole which required to change to pentamidine was 13.3%. During hospital admission, 16.6% of the patients died, and the survivors had mortality rates of 4% and 85% after 3 and 20 months, respectively.
Fortún
J
J
Unidad de Enfermedades Infecciosas, Hospital Ramón y Cajal, Madrid.
Hermida
J M
JM
Hernández-Cabrero
J
J
Martí-Belda
P
P
Sueiro
A
A
Fogué
L
L
Sanz
I
I
Buzón
L
L
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D005260:Female; D015497:HIV-1; D006761:Hospitals; D006801:Humans; D008297:Male; D008875:Middle Aged; D011020:Pneumonia, Pneumocystis / Q000150:complications* / Q000175:diagnosis; D012189:Retrospective Studies; D013030:Spain
Neumonía por Pneumocystis carinii en pacientes con infección por VIH en un hospital español.