Chemometric investigation of some analytical methods used for the chemical test of foetal lung maturity.
The lecithin/sphingomyelin (L/S) ratio is particularly important for the prediction of foetal lung maturity. A package for pattern recognition of analytical chemical data, "Parvus", was used to handle the different values of the L/S ratio obtained experimentally by common amperometric, spectrometric and chromatographic methods for the determination of lecithin. Eight subjects were considered and some interesting conclusions drawn on the equivalence of different analytical methods of determining lecithin in amniotic fluid.
Campanella
L
L
Department of Chemistry, Rome University La Sapienza, Italy.
Sammartino
M P
MP
Tomassetti
M
M
Visco
G
G
D000328:Adult; D000653:Amniotic Fluid / Q000737:chemistry; D003201:Computers; D005260:Female; D005333:Fetus / Q000378:metabolism; D006801:Humans; D007202:Indicators and Reagents; D008168:Lung / Q000737:chemistry* / Q000254:growth & development; D010363:Pattern Recognition, Automated; D010713:Phosphatidylcholines / Q000032:analysis; D011247:Pregnancy; D013109:Sphingomyelins / Q000032:analysis
D007202:Indicators and Reagents; D010713:Phosphatidylcholines; D013109:Sphingomyelins