Estrogen-progestogen replacement and cancer risk.
The increasing popularity of hormone replacement has focused renewed attention on the issue of whether certain sex steroids predispose to--or exert a protective effect against--various forms of carcinoma. In particular, the impact of the sex hormones on the pathogenesis of breast cancer remains highly controversial. Published reports have failed to demonstrate a clear relationship.
Gambrell
R D
RD
Department of Obstetrics-Gynecology, Medical College of Georgia, Augusta.
D000230:Adenocarcinoma / Q000139:chemically induced; D000368:Aged; D001943:Breast Neoplasms / Q000139:chemically induced; D015914:Estrogen Replacement Therapy / Q000009:adverse effects*; D004967:Estrogens / Q000378:metabolism / Q000494:pharmacology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009369:Neoplasms / Q000139:chemically induced*; D011374:Progesterone / Q000009:adverse effects / Q000627:therapeutic use; D012306:Risk; D014594:Uterine Neoplasms / Q000139:chemically induced
D004967:Estrogens; D011374:Progesterone