A non-hormonal therapeutic alternative in cervico-vaginal dystrophies.
The pharmaco therapeutic effect of polydeoxyribonucleotide vaginal suppositories in two dosages (PDRN 1,65 mg and PDRN 5 mg)* on vaginal dystrophy was studied. 40 women, aged more than forty, in surgical or physiological climacteric with cervico-vaginal dystrophy were examined. The study was carried out according to the double-blind method, randomized, between groups. Both treatments produced important ameliorations of subjective symptomatology and objective signs. No significant difference emerged between the two preparations. PDRN was proved to be a valid alternative to local hormonal therapies.
Maresi
M P
MP
Divisione Ostetrico Ginecologica, Ospedale di Livorno.
Baldi
L
L
Balatresi
L
L
Bogi
G
G
Civello
T
T
Cosimi
A
A
De Santis
R
R
Guarnotta
M
M
Baisi
F
F
Parente
A
A
D000287:Administration, Topical; D000328:Adult; D000368:Aged; D002584:Cervix Uteri / Q000473:pathology; D003127:Colposcopy; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008875:Middle Aged; D011089:Polydeoxyribonucleotides / Q000008:administration & dosage*; D013488:Suppositories; D002577:Uterine Cervical Diseases / Q000188:drug therapy* / Q000473:pathology; D014621:Vagina / Q000473:pathology; D014623:Vaginal Diseases / Q000188:drug therapy* / Q000473:pathology; D014626:Vaginal Smears
D011089:Polydeoxyribonucleotides; D013488:Suppositories