title: Potential value of immunoperoxidase technique in assessment of genital herpes.
abstract: Cervicovaginal smears from 86 patients with suspicious genital herpes were screened by routine Papanicolaou stain. The slides were then destained and restained by a commercial immunoperoxidase kit for the detection of herpes simplex virus. Results were compared with standard viral cultures performed on the same lesions. A statistically significant difference (P less than 0.05) was observed between the results of Papanicolaou-stained cytology and the immunoperoxidase technique. This study suggests that the immunoperoxidase technique is a rapid and reliable method of confirming a suspected diagnosis of herpetic infection. It is particularly useful in those patients without prenatal care who present in early labor when a rapid diagnostic test is required.
authors.affiliation: University of Florida College of Medicine, Gainesville.
authors.forename: S
authors.initials: S
authors.lastname: Masood
authors.forename: I
authors.initials: I
authors.lastname: Hosein
authors.forename: M
authors.initials: M
authors.lastname: Pitcher
authors.forename: W
authors.initials: W
authors.lastname: Graf
mesh_terms: D003362:Cost-Benefit Analysis; D005260:Female; D006558:Herpes Genitalis / Q000175:diagnosis*; D006801:Humans; D007124:Immunoenzyme Techniques / Q000191:economics; D065006:Papanicolaou Test; D011933:Reagent Kits, Diagnostic / Q000191:economics; D014626:Vaginal Smears
chemical_list: D011933:Reagent Kits, Diagnostic