title: Does a tetracycline resistance determinant of class N exist?
abstract: pMV120 was reported to carry the tetracycline resistance (Tcr) determinant of class N. We obtained tetracycline-susceptible transconjugants harboring plasmids with restriction enzyme profiles indistinguishable from those of pMV120 isolated from tetracycline-resistant clones. We conclude that pMV120 is a cryptic plasmid and that class N of Tcr determinants does not exist.
authors.affiliation: Laboratoire des Staphylocoques et des Streptocoques, Institut Pasteur, Paris, France.
authors.forename: T
authors.initials: T
authors.lastname: Horaud
authors.forename: F
authors.initials: F
authors.lastname: Delbos
authors.forename: K
authors.initials: K
authors.lastname: Pepper
mesh_terms: D003001:Cloning, Molecular; D013293:Enterococcus faecalis / Q000187:drug effects / Q000235:genetics; D008826:Microbial Sensitivity Tests; D010957:Plasmids; D013752:Tetracycline / Q000494:pharmacology*; D013753:Tetracycline Resistance
chemical_list: D013752:Tetracycline