Antibody to blood group glycosyltransferases in a patient transplanted with an ABO incompatible bone marrow.
In the plasma of a blood group B recipient who was transplanted with a blood group O bone marrow, we investigated an antibody to inhibit the activities of blood group A- and B-glycosyltransferases. When B lymphocytes from the patient were transformed with Epstein-Barr virus, a few clones producing antibodies to B-transferase were obtained.
Kominato
Y
Y
Department of Legal Medicine, Toyama Medical and Pharmaceutical University, Japan.
Fujikura
T
T
Takizawa
H
H
Hayashi
K
K
Mori
T
T
Matsue
K
K
Yasue
S
S
Matsuda
T
T
D000017:ABO Blood-Group System / Q000276:immunology*; D000328:Adult; D001402:B-Lymphocytes / Q000276:immunology; D001787:Blood Group Incompatibility / Q000276:immunology*; D016026:Bone Marrow Transplantation / Q000276:immunology*; D002999:Clone Cells / Q000276:immunology; D003429:Cross Reactions; D005700:Galactosyltransferases / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis / Q000276:immunology; D007075:Immunoglobulin M / Q000096:biosynthesis / Q000276:immunology; D007518:Isoantibodies / Q000276:immunology*; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000601:surgery; D008297:Male; D017350:N-Acetylgalactosaminyltransferases; D014184:Transplantation, Homologous
D000017:ABO Blood-Group System; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007518:Isoantibodies; D005700:Galactosyltransferases; D017350:N-Acetylgalactosaminyltransferases; C003742:UDPgalactosamine-galactose acetylgalactosaminyltransferase; C023155:blood-group-substance alpha-D-galactosyltransferase