Pseudohyperaldosteronism from liquorice-containing laxatives.
Four cases of pseudohyperaldosteronism due to chronic ingestion of liquorice-containing laxatives are described. All patients had hypertension and hypokalemia with suppression of plasma renin activity and aldosterone; the diagnosis was based only on retrospective grounds. In patients with hypokalemia and hypertension a possibility of such a cause must be excluded to avoid unnecessary diagnostic procedures.
Scali
M
M
Istituto di Semeiotica Medica, University of Padova, Italy.
Pratesi
C
C
Zennaro
M C
MC
Zampollo
V
V
Armanini
D
D
D000328:Adult; D000368:Aged; D000450:Aldosterone / Q000097:blood; D002400:Cathartics / Q000009:adverse effects*; D004338:Drug Combinations; D005260:Female; D006035:Glycyrrhiza; D006801:Humans; D006929:Hyperaldosteronism / Q000097:blood / Q000139:chemically induced* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D010936:Plant Extracts / Q000009:adverse effects; D010938:Plant Oils / Q000009:adverse effects; D010946:Plants, Medicinal; D011188:Potassium / Q000097:blood; D012083:Renin / Q000097:blood; D012676:Senna Extract / Q000009:adverse effects; D013148:Spironolactone / Q000627:therapeutic use
D002400:Cathartics; D004338:Drug Combinations; C069073:Midro; D010936:Plant Extracts; D010938:Plant Oils; C069074:liquorice decocta; D013148:Spironolactone; D000450:Aldosterone; D012676:Senna Extract; D012083:Renin; D011188:Potassium