[What are the indications for digitalis glycosides in the current treatment of cardiac insufficiency?].
Digitalis was discovered over two centuries ago and has been in everyday use for 100 years: however nowadays it is not considered to be the almost exclusive treatment of heart failure as it used to be with diuretic therapy. In the last decade, our understanding of the physiopathology of heart failure and the body's mechanisms of adaptation have improved and this has lead to the use of new molecules and a different approach to the problem of left ventricular failure. The classical contra-indications and precautions of use of digitalis have been studied in detail. The use of digitalis is contested especially in patients in sinus rhythm or with ischemic heart disease and it is used less often in adult cardiac emergencies. The competition between digitalis and vasodilator therapy is now very apparent in some situations; however, the choice between these two groups of drugs (as treatment of first intention or in association) has to be carefully considered in each individual case. The future of digitalis therapy lies without doubt in pediatric cardiology where it remains irreplaceable.
Louis
P
P
Centre de cardiologie, hôpital du Bocage, CHRU, Dijon.
Morelon
P
P
Fraison
M
M
André
F
F
Eicher
J C
JC
Girardot
C
C
Petit
A
A
D002986:Clinical Trials as Topic; D004071:Digitalis Glycosides / Q000627:therapeutic use*; D004232:Diuretics / Q000627:therapeutic use; D004358:Drug Therapy / Q000639:trends; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D015337:Multicenter Studies as Topic; D011897:Random Allocation; D014665:Vasodilator Agents / Q000627:therapeutic use
D004071:Digitalis Glycosides; D004232:Diuretics; D014665:Vasodilator Agents
Que reste-t-il des indications des digitaliques dans le traitement actuel de l'insuffisance cardiaque?