Pulmonary edema and hydrothorax in swine produced by fumonisin B1, a toxic metabolite of Fusarium moniliforme.
Pulmonary edema and hydrothorax were observed in mature swine that died approximately 5 days after consuming corn screenings. These postmortem observations were reproduced in younger swine (16-24 kg) that died within 1 week when fed the corn screenings under experimental conditions. Additionally, pulmonary edema and hydrothorax occurred in a pig (7.1 kg) that died after receiving 4 daily intravenous injections of fumonisin B1. A fungus was isolated from the corn screenings that is identical to Fusarium moniliforme MRC-826 in colony morphology and under microscopic examination.
Harrison
L R
LR
Veterinary Diagnostic and Investigational Laboratory, University of Georgia, Tifton 31794.
Colvin
B M
BM
Greene
J T
JT
Newman
L E
LE
Cole
J R
JR
D000821:Animal Feed / Q000032:analysis / Q000506:poisoning*; D000818:Animals; D002851:Chromatography, High Pressure Liquid; D005516:Food Microbiology; D037341:Fumonisins; D005670:Fusarium / Q000302:isolation & purification; D006876:Hydrothorax / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary*; D008099:Liver / Q000473:pathology; D008168:Lung / Q000473:pathology; D009183:Mycotoxins / Q000032:analysis / Q000506:poisoning*; D010179:Pancreas / Q000473:pathology; D011654:Pulmonary Edema / Q000139:chemically induced / Q000473:pathology / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000139:chemically induced* / Q000473:pathology; D003313:Zea mays
D037341:Fumonisins; D009183:Mycotoxins; C056933:fumonisin B1