[Defects in the prostaglandin system. IX. Lipoxygenase defect of thrombocytes in a patient with polycythemia vera].
Patients with the myeloproliferative syndrome (MPS) often show morphological and functional platelet abnormalities and an increased incidence of lowered cyclooxygenase- and/or lipoxygenase activity. We present the case history of a 68-year-old male patient with polycythaemia vera in whom an absolute absence of platelet lipoxygenase activity has been detected for the first time in the literature.
Sinzinger
H
H
Atheroskleroseforschungsgruppe (ASF) Wien.
Gisslinger
H
H
Linkesch
W
W
Peskar
B A
BA
D000368:Aged; D001792:Blood Platelets / Q000201:enzymology*; D006801:Humans; D008084:Lipoxygenase / Q000172:deficiency*; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D009101:Multiple Myeloma / Q000201:enzymology; D010974:Platelet Aggregation / Q000502:physiology; D010979:Platelet Function Tests; D011087:Polycythemia Vera / Q000201:enzymology*; D013929:Thromboxane B2 / Q000097:blood
D008315:Malondialdehyde; D013929:Thromboxane B2; D008084:Lipoxygenase
Defekte im Prostaglandinsystem. IX. Lipoxygenasedefekt der Thrombozyten bei einem Patienten mit Polycythaemia vera.