title: Immunocytochemical localization of taurine within glial cells in the optic nerve of adult albino rats.
abstract: Taurine immunoreactivity in one micron sections of the adult rat optic nerve was observed using light microscopy. Prominent staining was seen in glial cell somata in the perinuclear region and in their processes throughout the nerve, particularly in endfeet on capillaries and in the peripheral basal lamina (glia limitans). Axons and blood vessels showed relatively little or no staining in the mature nerve. The pattern of glial fibrillary acidic protein immunoreactivity on subsequent sections was similar in many respects to that of taurine, suggesting that a sub-population of taurine immunoreactive glial cells are optic nerve astrocytes.
authors.affiliation: Department of Physiology, McGill University, Montreal, Quebec, Canada.
authors.forename: N
authors.initials: N
authors.lastname: Lake
authors.forename: C
authors.initials: C
authors.lastname: Verdone-Smith
mesh_terms: D000818:Animals; D001253:Astrocytes / Q000737:chemistry; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000378:metabolism; D007124:Immunoenzyme Techniques; D008297:Male; D009457:Neuroglia / Q000737:chemistry*; D009900:Optic Nerve / Q000737:chemistry* / Q000166:cytology; D051381:Rats; D011919:Rats, Inbred Strains; D013654:Taurine / Q000032:analysis*
chemical_list: D005904:Glial Fibrillary Acidic Protein; D013654:Taurine