Gangrenous and/or perforated appendix: clinical outcome and in vitro susceptibility testing.
The data from this study indicate that cefoxitin was effective and generally well tolerated in the management of gangrenous and/or perforated appendicitis. No strong correlation was identified between in vitro susceptibility testing results and clinical outcome.
Finegold
S M
SM
University of California, Los Angeles.
Bennion
R S
RS
Thompson
J E
JE
Wexler
H M
HM
Baron
E J
EJ
D001064:Appendicitis / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D001441:Bacteroides fragilis / Q000187:drug effects; D002440:Cefoxitin / Q000627:therapeutic use*; D015296:Ceftizoxime / Q000627:therapeutic use*; D004311:Double-Blind Method; D005734:Gangrene; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology; D008826:Microbial Sensitivity Tests; D011446:Prospective Studies; D012422:Rupture, Spontaneous
D002440:Cefoxitin; D015296:Ceftizoxime