Syphilitic placentitis: demonstration of Treponema pallidum by immunoperoxidase staining.
We report a case of early congenital syphilis in which the placenta showed diffuse proliferative villitis and Treponema pallidum was identified by indirect immunoperoxidase stain in formalin-fixed paraffin-embedded placental tissue. This is the first report demonstrating T. pallidum in placental tissue using an immunohistochemical method.
Ohyama
M
M
Department of Neonatology, Kanagawa Children's Medical Center, Yokohama-city, Japan.
Itani
Y
Y
Tanaka
Y
Y
Goto
A
A
Sasaki
Y
Y
D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007231:Infant, Newborn; D010920:Placenta / Q000382:microbiology; D010922:Placenta Diseases / Q000209:etiology / Q000382:microbiology / Q000473:pathology*; D011247:Pregnancy; D013590:Syphilis, Congenital / Q000382:microbiology / Q000473:pathology*; D014210:Treponema pallidum / Q000302:isolation & purification*