Use of mouse tail in the study of irradiated microvasculature.
The use of the mouse tail in the study of microvasculature following fractionated radiotherapy is described. Mice are restrained in a perspex housing and mounted on a perspex tray containing slots for individual mice. The mouse restrainer, irradiation set up, and dosimetry are described in detail. Irradiation was carried out using a 4MV Linear accelerator. The technique described here is reproducible. It can be used to study the volume effects in fractionated radiotherapy.
Narayan
K
K
Peter MacCallum Cancer Institute, Melbourne, Vic, Australia.
D000818:Animals; D016319:Corrosion Casting; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008833:Microcirculation / Q000528:radiation effects*; D010315:Particle Accelerators; D011829:Radiation Dosage; D011882:Radiotherapy, High-Energy; D013623:Tail / Q000098:blood supply*