title: Acute CNS infection by Trypanosoma cruzi (Chagas' disease) in immunosuppressed patients.
abstract: Acute CNS involvement by Trypanosoma cruzi is uncommon. We report 2 immunosuppressed patients, 1 adult who developed an acute meningoencephalitis, and 1 child who presented with the tumor-like form of the disease. Both patients acquired the disease through blood transfusion. Blood donors migrating from endemic areas can transmit the disease in nonendemic countries if they are not routinely screened for antibodies to T cruzi.
authors.affiliation: Instituto de Investigaciones Neurologicas Dr. Raul Carrea-FLENI, Buenos Aires, Argentina.
authors.forename: R
authors.initials: R
authors.lastname: Leiguarda
authors.forename: A
authors.initials: A
authors.lastname: Roncoroni
authors.forename: A L
authors.initials: AL
authors.lastname: Taratuto
authors.forename: L
authors.initials: L
authors.lastname: Jost
authors.forename: M
authors.initials: M
authors.lastname: Berthier
authors.forename: M
authors.initials: M
authors.lastname: Nogues
authors.forename: H
authors.initials: H
authors.lastname: Freilij
mesh_terms: D000208:Acute Disease; D000328:Adult; D014355:Chagas Disease / Q000134:cerebrospinal fluid / Q000209:etiology*; D002648:Child; D003937:Diagnosis, Differential; D006801:Humans; D007108:Immune Tolerance; D007165:Immunosuppression Therapy; D008297:Male; D008590:Meningoencephalitis / Q000134:cerebrospinal fluid / Q000209:etiology*; D065227:Transfusion Reaction