title: [Cytogenetic activity of the pesticides cyclophos and alvison, their components and metabolites].
abstract: Two new pesticide preparations of cyclophos and alvison, a number of their components, two alvison metabolites have been studied to reveal their cytogenetic activity. According to the investigation in vivo the mutagenic effect of cyclophos manifests itself only with toxic doses. Professional contacts with the pesticide don't induce chromosome mutation in human peripheral lymphocytes. The alvison preparations generate chromosome mutations in somatic cells of people and animals. The components and metabolites of alvison have shown no visible genetic activity during in vivo and in vitro experiments.
authors.forename: L S
authors.initials: LS
authors.lastname: Stepanova
mesh_terms: D000818:Animals; D002869:Chromosome Aberrations / Q000235:genetics*; D006540:Herbicides / Q000378:metabolism / Q000633:toxicity*; D006801:Humans; D007306:Insecticides / Q000378:metabolism / Q000633:toxicity*; D051379:Mice; D009153:Mutagens; D016273:Occupational Exposure; D011122:Polyphosphates / Q000378:metabolism / Q000633:toxicity*; D013450:Sulfones / Q000378:metabolism / Q000633:toxicity*
chemical_list: D006540:Herbicides; D007306:Insecticides; D009153:Mutagens; D011122:Polyphosphates; D013450:Sulfones; C069470:alvison 8; C022074:sodium tetrametaphosphate
vernacular_title: Issledovanie tsitogeneticheskoĭ aktivnosti pestitsidov tsikofosa i alvisona, ikh komponentov i metabolitov.