[Non-A, non-B posttransfusion hepatitis after cardiopulmonary bypass].
One hundred and eight patients who required transfusion during and after cardiopulmonary bypass, and were followed for more than three months postoperatively. Non-A, non-B posttransfusion hepatitis (NANB-PTH) occurred in 19 patients (17.6%) between three and twelve weeks after the operation. The patients who developed NANB-PTH had received a large amount of blood transfusion than those who had not (24 +/- 12 Units versus 16 +/- 10 Units, p less than 0.05). The mean age of the former was 48 +/- 18 year-old and that of the latter was 33 +/- 24 year-old (p less than 0.05). The difference of the cardiopulmonary bypass time between them was not significant. The mean age and number of transfused blood units between the male and female patients were statistically not significant. However the incidence of NANB-PTH in male (13 of 54 patients, 24.1%) was higher than that (5 of 54 patients, 9.3%) in female (p less than 0.05).
Misawa
Y
Y
Department of Thoracic and Cardiovascular Surgery, Jichi Medical School, Tochigi, Japan.
Hasegawa
T
T
Fukusima
K
K
Yamaguchi
T
T
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D002315:Cardiopulmonary Bypass; D002648:Child; D002675:Child, Preschool; D005260:Female; D006526:Hepatitis C / Q000453:epidemiology / Q000635:transmission*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D013997:Time Factors; D065227:Transfusion Reaction