title: [The alkaline phosphatase activity of the blood serum as a factor reflecting the chronic inflammatory process in the skin in generalized forms of psoriasis, neurodermatitis, eczema and trophic ulcers].
abstract: Blood serum alkaline phosphatase (AP) level was found elevated in the patients suffering from eczema, neurodermatitis, eczema with large skin sites involved, and in those with trophic ulcers of various origins, as against normal subjects and reference patients with sarcoidosis and Kaposi's sarcoma. Elevated level of the enzyme activity is directly related to exacerbation stage and size of the skin site involved; this level reduced after therapy and this reduction was associated with clinical improvement. No concomitant visceral abnormalities (calculous cholecystitis, liver cirrhosis, or malignant tumors) were detected in the examinees, that might influence the blood serum AP activity.
authors.forename: I E
authors.initials: IE
authors.lastname: Khazizov
authors.forename: I V
authors.initials: IV
authors.lastname: Matukhin
mesh_terms: D000469:Alkaline Phosphatase / Q000097:blood*; D002908:Chronic Disease; D004796:Clinical Enzyme Tests; D003876:Dermatitis, Atopic / Q000175:diagnosis*; D004485:Eczema / Q000175:diagnosis*; D006801:Humans; D010373:Lice Infestations / Q000175:diagnosis; D011565:Psoriasis / Q000175:diagnosis*; D012507:Sarcoidosis / Q000175:diagnosis; D012514:Sarcoma, Kaposi / Q000175:diagnosis; D012532:Scabies / Q000175:diagnosis; D012871:Skin Diseases / Q000175:diagnosis; D012878:Skin Neoplasms / Q000175:diagnosis; D012883:Skin Ulcer / Q000175:diagnosis*
chemical_list: D000469:Alkaline Phosphatase
vernacular_title: Ob aktivnosti shchelochnoĭ fosfatazy syvorotki krovi kak faktore, otrazhaiushchem khronicheskiĭ vospalitel'nyĭ protsess v kozhe pri generalizovannykh formakh psoriaza, neĭrodermita, ékzemy i troficheskikh iazvakh.