title: A low-incidence red cell antigen JAL associated with two unusual Rh gene complexes.
abstract: A multilaboratory investigation during several years has identified a low incidence antigen JAL on the red cells of 7 propositi. JAL appears to be associated with two unusual Rh complexes, one of which produces a depressed C antigen and the other a depressed c antigen. Family studies strongly suggest that the JAL antigen is encoded by the RH locus. Anti-JAL has been implicated in haemolytic disease of the newborn and is thus considered to be a clinically significant antibody.
authors.affiliation: Medical Research Council Blood Group Unit, London, UK.
authors.forename: C
authors.initials: C
authors.lastname: Lomas
authors.forename: J
authors.initials: J
authors.lastname: Poole
authors.forename: N
authors.initials: N
authors.lastname: Salaru
authors.forename: M
authors.initials: M
authors.lastname: Redman
authors.forename: K
authors.initials: K
authors.lastname: Kirkley
authors.forename: M
authors.initials: M
authors.lastname: Moulds
authors.forename: J
authors.initials: J
authors.lastname: McCreary
authors.forename: G S
authors.initials: GS
authors.lastname: Nicholson
authors.forename: H
authors.initials: H
authors.lastname: Hustinx
authors.forename: C
authors.initials: C
authors.lastname: Green
mesh_terms: D005260:Female; D006801:Humans; D007518:Isoantibodies / Q000096:biosynthesis / Q000235:genetics* / Q000276:immunology; D007519:Isoantigens / Q000032:analysis / Q000235:genetics* / Q000276:immunology; D008297:Male; D015337:Multicenter Studies as Topic; D012204:Rh-Hr Blood-Group System / Q000235:genetics* / Q000276:immunology
chemical_list: D007518:Isoantibodies; D007519:Isoantigens; D012204:Rh-Hr Blood-Group System