Neurocutaneous melanosis, neurofibromatosis and spinal meningioma: an unusual association.
The case of 38-year-old woman bearer of a congenital giant naevus "en pélerine" with numerous neurofibromas and other satellite naevi was reported: the patient was afflicted by spastic tetraparesis, more pronounced on the right side. MRIscan of the spine revealed the presence of a cervical spinal tumor shown histologically to be a psammomatous meningioma. The skin picture was consistent with neurocutaneous melanosis; the rarity of its association with neurofibromatosis and spinal meningioma is discussed in the light of embryologic arguments.
Barbieri
F
F
Università di Napoli, II Facoltà di Medicina e Chirurgia Clinica Neurologica I.
Santangelo
R
R
Indaco
A
A
De Furio
M
M
Buscaino
G A
GA
D000328:Adult; D005260:Female; D006801:Humans; D008548:Melanosis / Q000150:complications*; D008577:Meningeal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D008579:Meningioma / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D009456:Neurofibromatosis 1 / Q000150:complications*