[Demonstration of new substances released during acute inflammatory processes].
Various acute inflammatory reactions modify effector and immunoregulatory functions of neutrophils, macrophages and lymphocytes locally as well as at distance from the inflammatory focus. Non-specific defenses are augmented concomitantly. These phenomena have been related to low molecular weight peptides called phlogokines. These findings may contribute to a better knowledge of the inflammatory process, while phlogokines may be of potential therapeutic value.
Giroud
J P
JP
Département de Pharmacologie, Hôpital Cochin, Paris.
D000210:Acute-Phase Reaction / Q000276:immunology / Q000378:metabolism*; D000818:Animals; D007249:Inflammation / Q000378:metabolism*; D007694:Killer Cells, Natural / Q000378:metabolism; D008214:Lymphocytes / Q000378:metabolism; D008264:Macrophages / Q000378:metabolism; D051379:Mice; D009504:Neutrophils / Q000378:metabolism; D051381:Rats
Mise en évidence de nouvelles substances libérées au cours de processus inflammatoires aigus.