title: [Pulmonary fibrosis and autoimmune manifestations. A diagnostic problem].
abstract: A case of 54-year-old male who, during the development of a pulmonary fibrosis, showed extrapulmonary autoimmune symptoms (polyarthritis and hemolytic anemia), is presented. The antinuclear antibodies and rheumatoid factor positives have been described in up to 30% of the idiopathic pulmonary fibrosis, complicating the differential diagnosis with lung fibrosis caused by alterations of connective tissue. We discuss the prognosis and treatment of this difficult diagnosis.
authors.affiliation: Servicio de Medicina Interna III, Hospital General Gregorio Marañón, Universidad Complutense, Madrid.
authors.forename: V J
authors.initials: VJ
authors.lastname: González Ramallo
authors.forename: A
authors.initials: A
authors.lastname: Muiño Miguez
authors.forename: E
authors.initials: E
authors.lastname: Rodríguez de Castro
authors.forename: J S
authors.initials: JS
authors.lastname: Filgueira Rubio
mesh_terms: D000974:Antibodies, Antinuclear / Q000097:blood; D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000188:drug therapy; D001706:Biopsy; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D006801:Humans; D008168:Lung / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011658:Pulmonary Fibrosis / Q000175:diagnosis* / Q000188:drug therapy; D012217:Rheumatoid Factor / Q000097:blood
chemical_list: D000974:Antibodies, Antinuclear; D012217:Rheumatoid Factor
vernacular_title: Fibrosis pulmonar y manifestaciones autoinmunes. Un problema diagnóstico.