title: [The prognostic value of Jass' histopathological classification of cancer of the left colon and rectum].
abstract: Histological material from 121 patients who underwent surgery for cancer of the left colon and rectum was reexamined by two pathologists according to criteria put forward in Jass' histopathological classification. A prevalence of Jass' grades II (36.4%) and III (47.9%) were observed in this series. There was no correlation between the site of neoplasia but there was a clearly increased incidence of advanced stages C and D according to Dukes-Kirklin's classification within Jass' grades II, III and IV (p less than 0.005) and growth pattern, but not for the configuration of tubules. The new histopathological model proved to be more reliable in prognostic terms in the case of cancer of the rectum compared to that of the left colon, but at present its clinical significance is limited to specifying the site and stage of the neoplasia. The latter was found to be the most reliable prognostic parameter.
authors.affiliation: Istituto di Patologia Chirurgica, Università di Genova.
authors.forename: G B
authors.initials: GB
authors.lastname: Secco
authors.forename: R
authors.initials: R
authors.lastname: Fardelli
authors.forename: G
authors.initials: G
authors.lastname: Lapertosa
authors.forename: E
authors.initials: E
authors.lastname: Fulcheri
authors.forename: S
authors.initials: S
authors.lastname: Rovida
authors.forename: G B
authors.initials: GB
authors.lastname: Ratto
authors.forename: C
authors.initials: C
authors.lastname: Prior
mesh_terms: D000230:Adenocarcinoma / Q000145:classification / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003110:Colonic Neoplasms / Q000145:classification / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D012004:Rectal Neoplasms / Q000145:classification / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D012189:Retrospective Studies
vernacular_title: Valore prognostico della classificazione istopatologica di Jass nel cancro del colon sinistro e del retto.