title: The role of protein kinase C in growth control and the concept of carcinogenesis as a progressive disorder in signal transduction.
authors.affiliation: Comprehensive Cancer Center, Columbia University, New York, N.Y. 10032.
authors.forename: I B
authors.initials: IB
authors.lastname: Weinstein
mesh_terms: D000818:Animals; D001419:Bacteria / Q000378:metabolism; D002273:Carcinogens / Q000494:pharmacology; D002455:Cell Division; D002461:Cell Line, Transformed; D002471:Cell Transformation, Neoplastic / Q000187:drug effects; D003043:Cocarcinogenesis; D003106:Colon / Q000382:microbiology; D003110:Colonic Neoplasms / Q000209:etiology / Q000473:pathology; D004075:Diglycerides / Q000096:biosynthesis; D004789:Enzyme Activation / Q000187:drug effects; D005786:Gene Expression Regulation / Q000187:drug effects; D015972:Gene Expression Regulation, Neoplastic; D006133:Growth Substances / Q000494:pharmacology; D006801:Humans; D007527:Isoenzymes / Q000502:physiology; D009363:Neoplasm Proteins / Q000502:physiology; D011493:Protein Kinase C / Q000096:biosynthesis / Q000502:physiology*; D051381:Rats; D015398:Signal Transduction / Q000187:drug effects; D014407:Tumor Cells, Cultured
chemical_list: C011439:1,2-diacylglycerol; D002273:Carcinogens; D004075:Diglycerides; D006133:Growth Substances; D007527:Isoenzymes; D009363:Neoplasm Proteins; D011493:Protein Kinase C