title: Neuropsychological features of benign partial epilepsy in children.
abstract: Rolandic paroxysmal epilepsy (RPE) is a useful model for investigating the complex links between epilepsy and cognitive dysfunction. 44 children with RPE who met the following (among other) criteria: negative CT scan, freedom from drug treatment, and IQ greater than or equal to 80, were assigned to three subgroups by side of EEG focus: left, right and bilateral. A neuropsychological battery elicited small differences in cognitive performance between the whole group and the controls and among the subgroups, only partially correlated with EEG side. A follow-up assessment showed that the short falls had disappeared along with the seizures and EEG anomalies, thus confirming the benign nature of RPE. Our findings suggest too that the mere presence of paroxysmal cortical activity is enough to trigger cognitive dysfunction.
authors.affiliation: Unità Organica di Neurofisiopatologia, Policlinico di Perugia.
authors.forename: P
authors.initials: P
authors.lastname: D'Alessandro
authors.forename: M
authors.initials: M
authors.lastname: Piccirilli
authors.forename: C
authors.initials: C
authors.lastname: Tiacci
authors.forename: A
authors.initials: A
authors.lastname: Ibba
authors.forename: M
authors.initials: M
authors.lastname: Maiotti
authors.forename: T
authors.initials: T
authors.lastname: Sciarma
authors.forename: A
authors.initials: A
authors.lastname: Testa
mesh_terms: D002648:Child; D003071:Cognition; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000503:physiopathology / Q000523:psychology*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009420:Nervous System / Q000503:physiopathology*; D009483:Neuropsychological Tests; D012016:Reference Values