[Amoxicillin/clavulanic acid and trimethoprim in the treatment of urinary infection in primary care].
The effectiveness of amoxicillin/clavulanic acid (A/Cl) and trimetoprim (TMP) were compared in two different schedules: 10 days treatment and monodose, in 80 patients with, urinary tract infection (UTI) demonstrated by urine culture. The patients over 65 years, the males and those with underlying risk conditions randomly received A/Cl or TMP during 10 days. The rates of cure were 76.9% for A/Cl and 73.9% for TMP. The difference was not significant. Thirty-one patients without those features randomly received a short A/Cl course or a single dose of TMP. The rates of cure were 92.8% for A/Cl and 58.8% for TMP. The difference was statistically significant. It was concluded that, in our patients, complicated lower UTI have a similar response rate to a ten days course of A/Cl or TMP, whereas A/Cl for three days is more effective than a single TMP dose to treat noncomplicated lower UTI.
Casas Rodríguez
J
J
CAP La Mina, Unidad Docente del Programa de Medicina Familiar y Comunitaria de Barcelona.
Pallarés Robles
J
J
Guarga Rojas
A
A
Grifell Martín
E
E
Marquet Palomer
R
R
D000658:Amoxicillin / Q000627:therapeutic use*; D019980:Amoxicillin-Potassium Clavulanate Combination; D001437:Bacteriuria / Q000188:drug therapy / Q000382:microbiology; D002969:Clavulanic Acids / Q000627:therapeutic use*; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D011320:Primary Health Care; D012074:Remission Induction; D013997:Time Factors; D014295:Trimethoprim / Q000627:therapeutic use*; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology
D002969:Clavulanic Acids; D019980:Amoxicillin-Potassium Clavulanate Combination; D000658:Amoxicillin; D014295:Trimethoprim
Amoxicilina/ácido clavulánico y trimetoprim en el tratamiento de la infección urinaria en atención primaria.