title: [Experimental emphysema following intravenous injection of trypsin].
abstract: The injection of trypsin provokes a decrease of the circulating antiproteases. Its effect on an elastase-induced emphysema is negligible. Paradoxically, emphysema is quantitatively demonstrated in rats treated with trypsin alone: an influx of polymorphonuclear leucocytes into the lung is observed during the acute phase of experiment.
authors.affiliation: Unité de Recherche, I.N.S.E.R.M. U. n. 14, Vandoeuvre-les-Nancy.
authors.forename: E
authors.initials: E
authors.lastname: Reichart
authors.forename: F
authors.initials: F
authors.lastname: Plenat
authors.forename: P
authors.initials: P
authors.lastname: Boerkmann
authors.forename: J M
authors.initials: JM
authors.lastname: Vignaud
mesh_terms: D000818:Animals; D004646:Emphysema / Q000139:chemically induced* / Q000473:pathology / Q000503:physiopathology; D007275:Injections, Intravenous; D008168:Lung / Q000473:pathology; D008297:Male; D009504:Neutrophils / Q000473:pathology; D010196:Pancreatic Elastase / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D014357:Trypsin / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D010196:Pancreatic Elastase; D014357:Trypsin
vernacular_title: Emphysème expérimental consécutif à une injection intraveineuse de trypsine.