title: Malignant external otitis: utility of CT in diagnosis and follow-up.
abstract: Malignant external otitis is a severe bacterial infection of the bone and soft tissues of the base of the skull that is frequently difficult to diagnose. The effectiveness of antibiotic therapy is likewise difficult to assess. Serial computed tomographic (CT) scans were obtained in 11 consecutive patients with malignant external otitis at time of diagnosis and periodically after conclusion of antibiotic therapy. All patients demonstrated abnormalities of the external auditory canal, with or without bone destruction. Soft tissue or fluid in the middle ear and mastoid, around the eustachian tube, and in the parapharyngeal space (both pre- and poststyloid) was seen in greater than 50% of the cases. While remineralization of bone was not seen, soft-tissue disease improved dramatically, and recurrence or persistence could be corroborated by detection of more extensive soft-tissue changes. By delineating the extra- and intracranial extent of disease, serial CT scans enable one to make the diagnosis, determine the extent of infection, document recurrence, exclude progression, and confirm resolution of malignant external otitis.
authors.affiliation: Department of Otolaryngology, University of Pittsburgh School of Medicine, PA 15261.
authors.forename: J
authors.initials: J
authors.lastname: Rubin
authors.forename: H D
authors.initials: HD
authors.lastname: Curtin
authors.forename: V L
authors.initials: VL
authors.lastname: Yu
authors.forename: D B
authors.initials: DB
authors.lastname: Kamerer
mesh_terms: D001799:Blood Sedimentation; D001847:Bone Diseases / Q000000981:diagnostic imaging; D004424:Ear Canal / Q000000981:diagnostic imaging; D005147:Facial Bones / Q000000981:diagnostic imaging; D005500:Follow-Up Studies; D006801:Humans; D010032:Otitis Externa / Q000097:blood / Q000000981:diagnostic imaging*; D010608:Pharyngeal Diseases / Q000000981:diagnostic imaging; D011552:Pseudomonas Infections / Q000097:blood / Q000000981:diagnostic imaging*; D011550:Pseudomonas aeruginosa; D012008:Recurrence; D014057:Tomography, X-Ray Computed