Antitumour activities of copper-ATP complex on transplantable murine lymphoma.
A synthetic metal-nucleotide complex [Cu3(ATP)26H2O]2- has been found to have a significant tumour inhibitory effect on Dalton's lymphoma. Moreover, the haematopoietic system of the treated hosts is favourably disposed and the life span is much increased. It is noteworthy that the tumour inhibitory effect is enhanced by combination therapy.
Nayak
K K
KK
Department of Chemistry, Jadavpur University, Calcutta, India.
Maity
P
P
Bhattacharyya
R
R
Chatterjee
M
M
D000255:Adenosine Triphosphate / Q000494:pharmacology*; D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002286:Carcinoma, Ehrlich Tumor / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D002455:Cell Division / Q000187:drug effects; D003300:Copper / Q000494:pharmacology*; D003520:Cyclophosphamide / Q000008:administration & dosage; D004906:Erythrocyte Count / Q000187:drug effects; D008223:Lymphoma / Q000188:drug therapy* / Q000401:mortality / Q000473:pathology; D051379:Mice; D009368:Neoplasm Transplantation
D003300:Copper; D000255:Adenosine Triphosphate; D003520:Cyclophosphamide