title: [Hormonal profile and changes in platelet aggregation in menstrual migraine].
abstract: We evaluated the hormonal profile and the platelet function in a group of 20 patients with menstrual migraine and a control group of 10 healthy women. Plasma levels of estradiol, progesterone, FSH and LH, as well as betathromboglobulin, platelet factor 4 and platelet serotonin were measured in different phases of the menstrual cycle. The hormonal profile did not show significant differences between both groups. The patients with menstrual migraine had higher BTG, FP4 and serotonin levels in the premenstrual phase than the control group. The results of this study show that in premenstrual migraine a platelet hyperagregation develops during the premenstrual phase. This abnormality is not directly correlated with the hormonal fluctuations observed during the menstrual cycle.
authors.affiliation: Servicio de Neurología, Hospital General de Galicia, Clínico Universitario, Santiago de Compostela.
authors.forename: R
authors.initials: R
authors.lastname: Leira
authors.forename: F
authors.initials: F
authors.lastname: Martínez
authors.forename: J
authors.initials: J
authors.lastname: Castillo
authors.forename: J R
authors.initials: JR
authors.lastname: Rodríguez
authors.forename: M
authors.initials: M
authors.lastname: Lema
authors.forename: M
authors.initials: M
authors.lastname: Noya
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D005260:Female; D006728:Hormones / Q000097:blood*; D006801:Humans; D008597:Menstrual Cycle; D008881:Migraine Disorders / Q000097:blood* / Q000503:physiopathology; D010974:Platelet Aggregation / Q000502:physiology*
chemical_list: D006728:Hormones
vernacular_title: Perfil hormonal y alteración de la agregación plaquetaria en la migraña menstrual.