A case of Rh isoimmunization: should threatened first-trimester abortion be an indication for Rh immune globulin prophylaxis?
Despite the recommended 28 weeks' gestation antenatal, postnatal, and postabortion prophylaxis with Rh immune globulin, residual Rh immunization still occurs in Rh-negative women. We describe a patient whose history suggests development of an anti-D antibody after first-trimester bleeding. To our knowledge, this is the first such case reported in the English literature.
Dayton
V D
VD
Department of Laboratory Medicine and Pathology, Hennepin County Medical Center, Minneapolis, MN 55403.
Anderson
D S
DS
Crosson
J T
JT
Cruikshank
S H
SH
D000033:Abortion, Threatened / Q000150:complications* / Q000628:therapy; D000328:Adult; D005260:Female; D006801:Humans; D007116:Immunization, Passive; D007518:Isoantibodies / Q000032:analysis; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D012203:Rh Isoimmunization / Q000150:complications* / Q000628:therapy; D014592:Uterine Hemorrhage / Q000150:complications
D007518:Isoantibodies