title: Evaluation of a commercial enzyme immunoassay for detection of Mycoplasma pneumoniae specific immunoglobulin G antibodies.
abstract: A commercial enzyme immunoassay (Platelia Mycoplasma, Diagnostics Pasteur) for the diagnosis of Mycoplasma pneumoniae [corrected] infections was evaluated and found not to be suitable for the purpose. More than 80% of healthy persons and patients with non-Mycoplasma pneumoniae respiratory infection, all with a negative Mycoplasma pneumoniae complement fixation test, had a positive EIA. Paired sera did not show the positive correlation between a rise in complement fixation titre and the EIA ratio reported by the manufacturer.
authors.affiliation: Nesseria Department, Statens Seruministitut, Copenhagen, Denmark.
authors.forename: S A
authors.initials: SA
authors.lastname: Uldum
authors.forename: J
authors.initials: J
authors.lastname: Søndergård-Andersen
authors.forename: J
authors.initials: J
authors.lastname: Skov Jensen
authors.forename: K
authors.initials: K
authors.lastname: Lind
mesh_terms: D000907:Antibodies, Bacterial / Q000032:analysis*; D003168:Complement Fixation Tests; D005069:Evaluation Studies as Topic; D005189:False Positive Reactions; D006801:Humans; D007124:Immunoenzyme Techniques; D007074:Immunoglobulin G / Q000032:analysis; D009177:Mycoplasma pneumoniae / Q000276:immunology*; D011019:Pneumonia, Mycoplasma / Q000175:diagnosis / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial; D007074:Immunoglobulin G