[Clinical use of pharmacologic monitoring at a hospital community].
This study reveals the efficiency of phenobarbital, diphenilhidantoine, carbamazepine, valproic acid and teophyline serum levels for their correct adjustment within the concentration gap considered optimal to produce the desired pharmacological effect. A total population of 882 patients treated with the drugs previously named is studied and an important improvement in dose adjustment is observed during these years as a consequence of drug's serum level knowledge.
Arranz Peña
M I
MI
Hospital Ramón y Cajal de la Seguridad Social, Madrid.
Seijas Martínez-Echevarría
M V
MV
Aguado-Vega
M
M
Rubí Cervino
J
J
D002220:Carbamazepine / Q000097:blood / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004363:Drug Utilization; D006801:Humans; D010634:Phenobarbital / Q000097:blood / Q000627:therapeutic use*; D010672:Phenytoin / Q000097:blood / Q000627:therapeutic use; D011358:Product Surveillance, Postmarketing; D013030:Spain; D013806:Theophylline / Q000097:blood / Q000627:therapeutic use*; D014635:Valproic Acid / Q000097:blood / Q000627:therapeutic use*
D002220:Carbamazepine; D014635:Valproic Acid; D010672:Phenytoin; D013806:Theophylline; D010634:Phenobarbital
Utilización clínica de la monitorización farmacológica en una comunidad hospitalaria.