title: Axonal neuropathy with monoclonal IgG kappa that binds to a neurofilament protein.
abstract: We report a 74-year-old woman with a slowly progressive sensory motor axonal neuropathy and a monoclonal IgG-kappa that bound to a 68-kd axonal protein identified as the low molecular weight neurofilament protein. The sera of control subjects and disease controls did not bind to neurofilament protein.
authors.affiliation: Department of Neurology, University of Milan, Istituto Scientifico S. Raffaele, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Nemni
authors.forename: M L
authors.initials: ML
authors.lastname: Feltri
authors.forename: R
authors.initials: R
authors.lastname: Fazio
authors.forename: A
authors.initials: A
authors.lastname: Quattrini
authors.forename: I
authors.initials: I
authors.lastname: Lorenzetti
authors.forename: M
authors.initials: M
authors.lastname: Corbo
authors.forename: N
authors.initials: N
authors.lastname: Canal
mesh_terms: D000368:Aged; D001369:Axons; D004594:Electrophysiology; D005260:Female; D006801:Humans; D015151:Immunoblotting; D007074:Immunoglobulin G / Q000378:metabolism*; D007145:Immunoglobulin kappa-Chains / Q000378:metabolism*; D007381:Intermediate Filament Proteins / Q000378:metabolism*; D009422:Nervous System Diseases / Q000378:metabolism* / Q000473:pathology / Q000503:physiopathology; D010265:Paraproteinemias / Q000378:metabolism*; D013497:Sural Nerve / Q000473:pathology
chemical_list: D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains; D007381:Intermediate Filament Proteins