title: [The prevalence of arrhythmias and repolarization changes in patients with mild or moderate essential hypertension undergoing an exercise test. Their variations with different antihypertensive treatments].
abstract: 42 mild and moderate hypertensive patients treated with Verapamil, Atenolol and Xipamide were studied. Exercise tests (ET) were performed at the onset and after a month of therapy, in order to detect arrhythmias and repolarization change prevalence of ventricular arrhythmias (VA) was 23.7% and 11.9% for supraventricular arrhythmias (SVA). 45.2% of the exercise tests were considered positive, with a significant correlation with maximum pressure peak. Patients with left ventricular hypertrophy (LVH) showed a significant increase in VA and +ET prevalence (42.1% and 63.2%). After treatment, the prevalence for VA registered a slight decrease and an increase for SVA; these differences not being considered significant. +ET showed a significant decrease in all patients, as well as in those with previous LVH (21.4%, 26.3%). Only atenolol produced a significant decrease in the +ET of patients with previous LVH (75% to 12.5%).
authors.affiliation: Departamento de Cardiología y Cirugía Cardiovascular, Clínica Universitaria de Navarra.
authors.forename: F
authors.initials: F
authors.lastname: Soria
authors.forename: E
authors.initials: E
authors.lastname: Alegría
authors.forename: M
authors.initials: M
authors.lastname: Valdés
authors.forename: A
authors.initials: A
authors.lastname: García
authors.forename: T
authors.initials: T
authors.lastname: Vicente
authors.forename: M J
authors.initials: MJ
authors.lastname: Castello
mesh_terms: D000328:Adult; D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000453:epidemiology* / Q000209:etiology / Q000503:physiopathology; D001262:Atenolol / Q000627:therapeutic use; D004341:Drug Evaluation; D004452:Echocardiography; D005080:Exercise Test; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D008875:Middle Aged; D005082:Physical Exertion / Q000187:drug effects / Q000502:physiology*; D015995:Prevalence; D014700:Verapamil / Q000627:therapeutic use; D014988:Xipamide / Q000627:therapeutic use
chemical_list: D000959:Antihypertensive Agents; D014988:Xipamide; D001262:Atenolol; D014700:Verapamil
vernacular_title: Prevalencia de arritmias y alteraciones de la repolarización en pacientes hipertensos esenciales ligeros o moderados sometidos a prueba de esfuerzo. Sus variaciones con diferentes tratamientos antihipertensivos.