Leukemia L 1210 cells induce depletion of Lyt 2+ thymocytes.
The thymocytes were analyzed on the 7th day after i.p. inoculation of 10(6) leukemia L 1210 cells to syngeneic DBA/2 Wf mice. A three-fold decrease of the total number of thymocytes was found as well as 1.7-fold decrease of the per cent of thymocytes with Lyt 2+ phenotype, while the per cent of cells with phenotypes Thy 1.2+ and Lyt 1+ was unchanged.
Kawiak
J
J
Department of Cytophysiology, Medical Centre of Postgraduate Education, Warszawa, Poland.
Kawalec
M
M
D000818:Animals; D000950:Antigens, Ly / Q000032:analysis / Q000276:immunology*; D007939:Leukemia L1210 / Q000276:immunology*; D008212:Lymphocyte Depletion; D051379:Mice; D008811:Mice, Inbred DBA; D010641:Phenotype; D013601:T-Lymphocytes / Q000276:immunology*
D000950:Antigens, Ly