title: Ovulation and successful pregnancy in a woman with ovarian failure after hypophysectomy and gonadotropin therapy.
abstract: A 38-year-old woman ovulated and conceived after administration of human menopausal gonadotropins despite a previous diagnosis of ovarian failure at age 18. Possible explanations include restoration of down-regulated gonadotropin receptors by development of a prolactinoma, spontaneous remission of autoimmune oophoritis, or prior tumor secretion of biologically inert gonadotropins.
authors.affiliation: Department of Obstetrics and Gynecology, Cooper Hospital/University Medical Center, Robert Wood Johnson Medical School, Camden, New Jersey.
authors.forename: J H
authors.initials: JH
authors.lastname: Check
mesh_terms: D000236:Adenoma / Q000601:surgery; D000328:Adult; D005260:Female; D006801:Humans; D007016:Hypophysectomy; D008596:Menotropins / Q000627:therapeutic use*; D010049:Ovarian Diseases / Q000188:drug therapy*; D010060:Ovulation; D010911:Pituitary Neoplasms / Q000601:surgery; D011184:Postoperative Period; D011247:Pregnancy
chemical_list: D008596:Menotropins