title: Plasma osteocalcin in preparturient and postparturient cows: correlation with plasma 1,25-dihydroxyvitamin D, calcium, and inorganic phosphorus.
abstract: The purpose of the present study was to determine changes of plasma osteocalcin levels in periparturient cows and to examine the correlation of plasma osteocalcin level with that of 1,25-dihydroxyvitamin D, Ca, and inorganic P. Five Holstein-Friesian cows, aged 3 to 5 yr, were used from 5 d before to 15 d after calving. Concentration (mean +/- SE) of plasma osteocalcin decreased rapidly from d 1 prepartum, reached a low of 8.0 +/- 3.0 ng/ml at d 1 postpartum, and then recovered gradually to 17.8 +/- 3.8 ng/ml at 15 d after calving. In contrast, the concentration of plasma 1,25-dihydroxyvitamin D increased from calving to 3 d postpartum. Plasma concentrations of osteocalcin did not correlate significantly with those of 1,25-dihydroxyvitamin D, but it was significantly proportional to that of Ca and inorganic P. It is suggested that osteoblast function is depressed by a number of factors around the time of parturition.
authors.affiliation: Department of Veterinary Internal Medicine, Iwate University, Morioka, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Naito
authors.forename: N
authors.initials: N
authors.lastname: Shindo
authors.forename: R
authors.initials: R
authors.lastname: Sato
authors.forename: D
authors.initials: D
authors.lastname: Murakami
mesh_terms: D000818:Animals; D002117:Calcitriol / Q000097:blood; D002118:Calcium / Q000097:blood; D002417:Cattle / Q000097:blood*; D005260:Female; D007774:Lactation / Q000097:blood; D015675:Osteocalcin / Q000097:blood*; D010758:Phosphorus / Q000097:blood; D049590:Postpartum Period / Q000097:blood*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000097:blood*
chemical_list: D015675:Osteocalcin; D010758:Phosphorus; D002117:Calcitriol; D002118:Calcium