[Arterial hypertension following kidney transplantation in patients on conventional immunosuppressive therapy and in those on cyclosporin A].
The incidence and causes of arterial hypertension following 110 kidney transplantations in 109 patients were studied. Seventy-five patients with satisfactory renal function were observed over a period of more than a year. Of these, 46 + 2 patients received Azathioprin and 27 of them had arterial hypertension; of the 29 + 5 patients who received cyclosporin A, 18 had arterial hypertension. The incidence of hypertension and its levels were significantly higher in Azathioprin treated patients, than those on cyclosporin A treatment. Slight counter relation between arterial hypertension and blood cyclosporin A level was found. Arterial hypertension reached peak values during the first month with slight decrease on the third month, followed by further elevation. The basic reasons for arterial hypertension were rejection reactions, the own kidneys left in situ and arterial stenosis of the grafted kidney.
Beleva
B
B
D003524:Cyclosporins / Q000627:therapeutic use*; D006084:Graft Rejection / Q000276:immunology; D006801:Humans; D006973:Hypertension / Q000453:epidemiology* / Q000209:etiology / Q000401:mortality; D007165:Immunosuppression Therapy; D007676:Kidney Failure, Chronic / Q000150:complications / Q000401:mortality / Q000601:surgery; D016030:Kidney Transplantation / Q000276:immunology*; D011183:Postoperative Complications / Q000453:epidemiology* / Q000209:etiology / Q000401:mortality; D012189:Retrospective Studies; D013997:Time Factors
D003524:Cyclosporins
Arterialna khipertoniia sled bŭbrechna transplantatsiia pri bolni na konventsionalna imunosupresivna terapiia i takiva s tsiklosporin A.