[Changes in blood viscosity and erythrocyte deformability in patients with dyslipidemia treated with binifibrate].
31 patients afflicted with primary hyperlipidemia who did not improve after 30 days on a diet were treated with 1800 mg/day of binifibrate. We measured the total cholesterol level and triglyceridemia, as well as blood viscosity and red cell deformability at day 0, 30, 60, 90 of treatment. We found a statistically significant decrease in cholesterol and triglyceride levels as well as blood viscosity, and an increment of red cell deformability which improved the circulatory dynamisms augmentin the tissular perfusion in these patients.
Labiós Gómez
M
M
Servicio de Medicina Interna, Hospital Clínico Universitario, Facultad de Medicina, Valencia.
Romero Simo
M
M
Gabriel Botella
F
F
Martín Valles
H
H
Morera Llorca
M
M
Freixas Ventura
J
J
D000368:Aged; D001809:Blood Viscosity / Q000187:drug effects*; D004907:Erythrocyte Deformability / Q000187:drug effects*; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009539:Nicotinic Acids / Q000494:pharmacology* / Q000627:therapeutic use
D000960:Hypolipidemic Agents; D009539:Nicotinic Acids; C038877:binifibrate
Modificaciones de la viscosidad de la sangre y deformabilidad eritrocitaria en pacientes dislipémicos tratados con binifibrato.