title: [Chordoma (a review of 11 cases)].
abstract: Eleven cases of chordoma, localized at sacrum (3 cases), lumbar spine (6 cases), cervical spine (2 cases), are reported. Authors describe clinical and pathological findings of the tumor and underline peculiarity of spinal localization and difficulty of diagnosis, often delayed, particularly in sacral spine localizations. Radiotherapy and chemotherapy give poor results while surgery can be employed in the treatment on account of the slow evolution and of the not very frequent aptitude of the tumor to give metastases. However peculiar localization into the sacral spine allows to remove the whole tumor if only it is localized below the 2nd sacral vertebra; authors present such a case treated by means of subtotal resection of sacrum and coccyx. In proximal sacral localizations and in other spinal localizations, surgery is a palliative procedure and can only slow down the evolution of the tumor; recurrence is a rule, even in association with radiotherapy. However surgical treatment must be often performed because of myeloradicular involvement.
authors.affiliation: Istituto di Clinica Ortopedica, Università degli Studi di Sassari.
authors.forename: E
authors.initials: E
authors.lastname: De Santis
authors.forename: G
authors.initials: G
authors.lastname: Gasparini
authors.forename: F
authors.initials: F
authors.lastname: Pallotta
authors.forename: P
authors.initials: P
authors.lastname: Lisai
mesh_terms: D002574:Cervical Vertebrae; D002817:Chordoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae; D008297:Male; D012447:Sacrum; D013125:Spinal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy
vernacular_title: Cordoma (rassegna di 11 casi).