[Effect of bezamidine on plasma cholesterol and triglyceride levels in patients with familial hyperlipoproteinemia].
The hypolipidemic agent bezamidine, a fibroic acid derivative (KPKA, Yugoslavia), was applied to treat Types 2a, 2b, 4 and 5 familial hyperlipoproteinemias. The highest reduction in plasma cholesterol and triglyceride concentrations was found in patients with Types 2b, 4 and 5 familial hyperlipoproteinemias. No clear-cut adverse effects of the drug were found during 3 months.
Kukharchuk
V V
VV
Koshechkin
V A
VA
Konovalov
G A
GA
Rozhkova
T A
TA
Solov'eva
E Iu
EIu
D000293:Adolescent; D000328:Adult; D001550:Benzamidines / Q000627:therapeutic use*; D002784:Cholesterol / Q000097:blood*; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000097:blood / Q000188:drug therapy*; D006953:Hyperlipoproteinemia Type IV / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood*
D001550:Benzamidines; D000960:Hypolipidemic Agents; D014280:Triglycerides; D002784:Cholesterol; C032157:benzamidine
Vliianie bezamidina na kontsentratsii kholesterina i triglitseridov plazmy krovi u bol'nykh s semeĭnymi giperlipoproteidemiiami.