title: [Assisted circulation by external heterotopic prosthesis as a bridge to heart transplantation].
abstract: Eleven patients aged 7 to 58 years were placed on assisted circulation with Pierce (2 cases) or Abiomed (9 cases) external prosthetic ventricles as a bridge to cardiac transplantation. The indications were terminal cardiac failure following cardiomyopathy (7 cases), decompensated ischemic heart disease (3 cases) and subacute post-transplantation rejection (1 case). The duration of the assisted circulation ranged from 24 hours to 11 days. All patients were transplanted but 3 died after transplantation (27%). The circulatory assistance was satisfactory in all patients as shown by the regression of clinical signs of low cardiac output and the normalisation of diuresis. The complications observed during assisted circulation and after cardiac transplantation were: haemorrhage (36%), infection (27%) and thromboembolism (9%). These preliminary results with a 72% post-transplantation survival rate, show that both systems are effective "bridges to cardiac transplantation". The Abiomen device is excellent value for money and relatively simple to install and represents a good compromise between the sophisticated techniques of circulatory assistance and the problems of the cost of health care.
authors.affiliation: Service de chirurgie thoracique et cardiaque C, BP Lyon-Montchat.
authors.forename: J
authors.initials: J
authors.lastname: Ninet
authors.forename: M
authors.initials: M
authors.lastname: Vigneron
authors.forename: P
authors.initials: P
authors.lastname: Cochet
authors.forename: J
authors.initials: J
authors.lastname: Neidecker
authors.forename: M C
authors.initials: MC
authors.lastname: d'Agrosa
authors.forename: O
authors.initials: O
authors.lastname: Bastien
authors.forename: C
authors.initials: C
authors.lastname: de Riberolles
authors.forename: G
authors.initials: G
authors.lastname: Champsaur
mesh_terms: D000293:Adolescent; D000328:Adult; D001243:Assisted Circulation / Q000009:adverse effects / Q000191:economics / Q000401:mortality; D002648:Child; D003404:Creatinine / Q000097:blood; D004231:Diuresis; D005340:Fibrinogen / Q000032:analysis; D006084:Graft Rejection; D006331:Heart Diseases / Q000628:therapy; D016027:Heart Transplantation / Q000009:adverse effects / Q000401:mortality; D006353:Heart-Assist Devices; D006439:Hemodynamics; D006801:Humans; D008875:Middle Aged; D010976:Platelet Count
chemical_list: D005340:Fibrinogen; D003404:Creatinine
vernacular_title: Assistance circulatoire en attente de transplantation cardiaque par prothèse hétérotopique externe.