Influence of a bacterial extract on antigen presentation and protection against experimental infections.
Although substances known as immunodulators are usually used to stimulate nonspecific immunity, their mode of action is not well understood. In an effort to clarify this mechanism, we investigated the effect of a lyophilized bacterial extract (Broncho-Vaxom) on experimental infections, on normal or irradiated mice, and on antigen processing.
Fontanges
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French Army Medical Research Center, La Tronche.
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Cristau
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Burckhart
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D000276:Adjuvants, Immunologic / Q000008:administration & dosage*; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D000938:Antigen-Presenting Cells / Q000187:drug effects* / Q000276:immunology; D000956:Antigens, Viral / Q000276:immunology; D001419:Bacteria; D001424:Bacterial Infections / Q000276:immunology*; D002457:Cell Extracts; D007710:Klebsiella Infections / Q000276:immunology; D008264:Macrophages / Q000187:drug effects* / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D009894:Opportunistic Infections / Q000276:immunology; D011014:Pneumonia / Q000276:immunology; D011552:Pseudomonas Infections / Q000276:immunology; D014777:Virus Diseases / Q000276:immunology*; D000095983:Bacterial Lysates
D000276:Adjuvants, Immunologic; D000956:Antigens, Viral; D002457:Cell Extracts; C030259:Broncho-Vaxom; D000095983:Bacterial Lysates