Subglottic stenosis in Wegener's granulomatosis: development during cyclophosphamide treatment with response to carbon dioxide laser therapy.
A patient with Wegener's granulomatosis rapidly developed a circumferential subglottic stenosis while on a cyclophosphamide regimen that had caused resolution of systemic symptoms and pulmonary infiltrates. The stenosis developed in the area of previously noted tracheal ulceration and responded satisfactorily to carbon dioxide laser therapy.
Strange
C
C
Department of Medicine, Medical University of South Carolina, Charleston 29425.
Halstead
L
L
Baumann
M
M
Sahn
S A
SA
D000328:Adult; D002245:Carbon Dioxide; D003520:Cyclophosphamide / Q000009:adverse effects / Q000627:therapeutic use; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D053685:Laser Therapy; D011239:Prednisolone / Q000627:therapeutic use; D014135:Tracheal Stenosis / Q000139:chemically induced / Q000209:etiology* / Q000601:surgery
D002245:Carbon Dioxide; D003520:Cyclophosphamide; D011239:Prednisolone