Levels of 15-ketodihydroprostaglandin F2 alpha during experimental Toxoplasma gondii infection in non-pregnant ewe lambs.
In order to study the relation between prostaglandin F2 alpha levels and fever during Toxoplasma gondii infection, six non-pregnant ewe lambs were exposed orally to T. gondii oocysts and an additional four animals were used as non-inoculated controls. Rectal temperature was measured daily during four weeks and plasma samples were analysed for the content of 15-ketodihydroprostaglandin F2 alpha. As compared to controls, the inoculated animals had significantly elevated rectal temperatures on days 4-16 after infection, but no concomitant changes in prostaglandin F2 alpha metabolite levels were recorded.
Fredriksson
G
G
Department of Obstetrics and Gynaecology, Faculty of Veterinary Medicine, Swedish University of Agricultural Sciences, Uppsala.
Aiumlamai
S
S
Lundén
A
A
Amare
D
D
Uggla
A
A
D000818:Animals; D001831:Body Temperature; D015237:Dinoprost / Q000031:analogs & derivatives* / Q000097:blood; D005260:Female; D012756:Sheep; D012757:Sheep Diseases / Q000097:blood* / Q000503:physiopathology; D014124:Toxoplasmosis, Animal / Q000097:blood* / Q000503:physiopathology
C008228:15-keto-13,14-dihydroprostaglandin F2alpha; D015237:Dinoprost