[Effect of the treatment of Cushing's syndrome and primary obesity on the female reproductive system].
Basic parameters of the reproductive system were examined in 121 women with Icenko-Cushing's disease and in 87 ones with primary obesity before and after therapy. Icenko-Cushing's disease was treated with the means acting on the adrenals (chloditan, destruction of one or both adrenals, uni- or bilateral adrenalectomy) and on the hypothalamohypophyseal area (parlodel, peritol, nakom, R-therapy). Combined therapy of primary obesity included low-caloric diet (approximately 1200 kcal) with 1-2 fasting days weekly, a complex of therapeutic exercises, physio- and balneotherapy. The results permit a conclusion that pathogenetic therapy, resulting in a stable clinical and hormonal remission of Icenko-Cushing's disease and body mass reduction in primary obesity as a rule lead to recovery of the reproductive system functioning in such patients.
Manusharova
R A
RA
Veĭnberg
M E
ME
D000293:Adolescent; D000315:Adrenalectomy; D000328:Adult; D003131:Combined Modality Therapy; D003480:Cushing Syndrome / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008597:Menstrual Cycle / Q000502:physiology*; D008599:Menstruation Disturbances / Q000209:etiology* / Q000628:therapy; D009765:Obesity / Q000150:complications / Q000503:physiopathology / Q000628:therapy*
Vliianie lecheniia bolezni Itsenko-Kushinga i pervichnogo ozhireniia na reproduktivnuiu sistemu zhenshchin.