[HLA antigens in patients with rheumatoid arthritis, their relatives, and spouses].
The results of the comparison between phenotypic frequency of HLA antigen classes I and II in patients afflicted with rheumatoid arthritis (RA) and their relatives (study carried out in the east of Andalusian), showed a significant increase of HLA A24, B51, B44, CW1 ans CW5 class I antigen in the group of relatives. We found a statistically significant DR4 antigen class II increase in both, patients and relative groups. The marriage parther of patients with RA did not have variations in class I or II HLA antigens compared to the control group. We concluded that RA is probably related to the following antigens: A24, B51, B44, CW1, CW5 and DR4.
Mataran Pérez
L
L
Servicio de Reumatología, Hospital Clínico Universitario de Granada.
Rodríguez Pérez
M
M
González Domínguez
J
J
Gutiérrez Gea
F
F
Abellán Pérez
M
M
Salvatierra Ríos
D
D
D000293:Adolescent; D000328:Adult; D001172:Arthritis, Rheumatoid / Q000097:blood* / Q000235:genetics*; D005190:Family; D005260:Female; D006680:HLA Antigens / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D010641:Phenotype; D012307:Risk Factors
D006680:HLA Antigens
Estudio de los antígenos HLA en pacientes con artritis reumatoide, sus familiares y cónyuges.