title: Comparison of the sevenless genes of Drosophila virilis and Drosophila melanogaster.
abstract: The sevenless gene of Drosophila melanogaster encodes a transmembrane tyrosine kinase receptor required for normal eye development. We report here the isolation and DNA sequence analysis of the sevenless gene from Drosophila virilis. The predicted amino acid sequences of the sevenless proteins from these two species, which diverged approximately 60 million years ago, are compared.
authors.affiliation: Howard Hughes Medical Institute, University of California, Berkeley 94720.
authors.forename: W M
authors.initials: WM
authors.lastname: Michael
authors.forename: D D
authors.initials: DD
authors.lastname: Bowtell
authors.forename: G M
authors.initials: GM
authors.lastname: Rubin
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D003001:Cloning, Molecular; D015342:DNA Probes; D004330:Drosophila / Q000235:genetics*; D004331:Drosophila melanogaster / Q000235:genetics*; D015723:Gene Library; D005796:Genes; D008969:Molecular Sequence Data; D009154:Mutation; D010786:Photoreceptor Cells / Q000201:enzymology / Q000254:growth & development; D011505:Protein-Tyrosine Kinases / Q000235:genetics*; D012160:Retina / Q000254:growth & development; D012689:Sequence Homology, Nucleic Acid; D013045:Species Specificity
chemical_list: D015342:DNA Probes; D011505:Protein-Tyrosine Kinases