title: Extracorporeal shock wave lithotripsy. Experience in treating 245 patients with gallbladder stones.
abstract: An EDAP LT-01 lithotripter was used to treat 245 patients with functioning gallbladders containing one to three radiolucent stones of less than 20 mm in diameter. Ursodeoxycholic acid was administrated as adjuvant litholytic therapy. The gallbladder stones disintegrated in 98.8% of patients and disappeared completely in 21.2% within 1 month after lithotripsy, in 26.5% within 2 months, in 33.9, 40, 46.5, 48.6 and 53.9% within 3, 4, 6, 9, and 12 months, respectively. Adverse effects after lithotripsy were dull abdominal pain (49.4%), biliary colic (13.1%), jaundice (1.2%), and pancreatitis (0.4%). Extracorporeal shock wave lithotripsy combined with litholytic therapy is a non-invasive, painless, safe, and effective treatment in selected patients. Patients with solitary radiolucent stone less than 20 mm in diameter are considered candidates for extracorporeal shock wave lithotripsy (ESWL). The key to success of ESWL lies in the strict selection of patients, careful monitoring throughout the lithotriptic procedure, and enough litholytic therapy. The disadvantages of this method include strict selection of patients and high costs, poor curative effect, and recurrence of stones (11.4% of patients).
authors.affiliation: Department of Surgery, Zhongshan Hospital, Shanghai Medical University.
authors.forename: B S
authors.initials: BS
authors.lastname: Wang
authors.forename: G R
authors.initials: GR
authors.lastname: Xu
authors.forename: L Q
authors.initials: LQ
authors.lastname: He
authors.forename: Y W
authors.initials: YW
authors.lastname: Zhang
authors.forename: L W
authors.initials: LW
authors.lastname: Zheng
authors.forename: J X
authors.initials: JX
authors.lastname: Chen
authors.forename: S C
authors.initials: SC
authors.lastname: Lin
authors.forename: C W
authors.initials: CW
authors.lastname: Meng
mesh_terms: D000328:Adult; D000368:Aged; D002769:Cholelithiasis / Q000188:drug therapy / Q000628:therapy*; D005260:Female; D006801:Humans; D008096:Lithotripsy; D008297:Male; D008875:Middle Aged; D014580:Ursodeoxycholic Acid / Q000627:therapeutic use
chemical_list: D014580:Ursodeoxycholic Acid