title: [The effect of the osmotic pressure of the culture medium on cells of Francisella tularensis vaccinal strain 15].
abstract: The dependence of the growth rate of F. tularensis on the osmotic properties of the medium can be presented as a curve with the maximum in the area of 500-600 mOsm. Under these circumstances the intracellular osmotic pressure exceeds the extracellular one by 50-100 mOsm. With the rise of the osmotic pressure in the medium the increase of the concentration of K+ in the cells occurs. The energy-dependent accumulation of K+ in the cells at rest is activated by the rise of the osmotic pressure in the medium. F. tularensis are probably capable of osmoregulation, ensured by the energy-dependent osmosensitive K(+)-transporting system.
authors.forename: S A
authors.initials: SA
authors.lastname: Ivanov
authors.forename: I G
authors.initials: IG
authors.lastname: Govorunov
authors.forename: B V
authors.initials: BV
authors.lastname: Sakharov
authors.forename: E O
authors.initials: EO
authors.lastname: Puchkova
mesh_terms: D001692:Biological Transport; D003470:Culture Media / Q000494:pharmacology*; D005604:Francisella tularensis / Q000254:growth & development* / Q000378:metabolism; D009391:Nephelometry and Turbidimetry; D009997:Osmotic Pressure; D011188:Potassium / Q000378:metabolism
chemical_list: D003470:Culture Media; D011188:Potassium
vernacular_title: Vliianie osmoticheskogo davleniia kul'tural'noĭ sredy na kletki vaktsinnogo shtamma 15 Francisella tularensis.