Urinary excretion of metabolites of norepinephrine in Tourette's syndrome.
Urinary excretion of the norepinephrine metabolites 3-methoxy-4-hydroxyphenylethylene glycol (MHPG) and normetanephrine (NMR) was measured in Tourette's Syndrome (TS) patients and in control subjects matched for age and education. The 24-h excretion (expressed per gram of creatinine) of total MHPG and of free and total (free + conjugated) NME was significantly lower in TS patients than in the normal subjects.
Baker
G B
GB
Department of Psychiatry, University of Alberta, Edmonton, Canada.
Bornstein
R A
RA
Douglass
A B
AB
Carroll
A
A
King
G
G
D002648:Child; D002849:Chromatography, Gas; D006801:Humans; D008297:Male; D008734:Methoxyhydroxyphenylglycol / Q000652:urine; D009638:Norepinephrine / Q000652:urine*; D009647:Normetanephrine / Q000652:urine; D005879:Tourette Syndrome / Q000652:urine*
D009647:Normetanephrine; D008734:Methoxyhydroxyphenylglycol; D009638:Norepinephrine