Localization of CAI and CAII isoenzymes in normal term human placenta by immunofluorescence techniques.
The carbonic anhydrase isoenzymes, low activity CAI and high activity CAII, were localized in normal term human placenta by immunocytochemical techniques. Both CAI and CAII isoenzymes were present in the syncytial trophoblasts. Fetal erythrocytes in the placental capillaries also showed positive staining for both CAI and CAII isoenzymes. The possible physiological roles of CA in human placenta are also discussed.
Aliakbar
S
S
Department of Biochemistry, Kings College London, Strand, UK.
Brown
P R
PR
Nicolaides
K H
KH
D002256:Carbonic Anhydrases / Q000032:analysis*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005455:Fluorescent Antibody Technique; D005865:Gestational Age; D006801:Humans; D007527:Isoenzymes / Q000096:biosynthesis*; D010920:Placenta / Q000032:analysis*; D011247:Pregnancy
D007527:Isoenzymes; D002256:Carbonic Anhydrases