title: [Severe bradycardia and arterial hypotension following the administration of sublingual nitroglycerin].
abstract: Two patients with coronary artery disease who developed severe bradycardia (less than 40 beats/min) and hypotension (less than 65/...mmHg) in supine position following the administration of sublingual nitroglycerin in the course of an anginal pain are reported. The administration of intravenous atropine sulfate (1-1.5 mg) readily reverted both hypotension and bradycardia. In one patient this complication was observed three times; in this patient sublingual nifedipine (10 mg) was successfully used to treat subsequent anginal crisis.
authors.affiliation: Departamento de Medicina, Hospital General Vall d'Hebron, Barcelona.
authors.forename: E
authors.initials: E
authors.lastname: Sanz Girgas
authors.forename: M P
authors.initials: MP
authors.lastname: Tornos
authors.forename: G
authors.initials: G
authors.lastname: Permanyer Miralda
authors.forename: X
authors.initials: X
authors.lastname: Carner
authors.forename: J
authors.initials: J
authors.lastname: Soler Soler
mesh_terms: D000286:Administration, Sublingual; D001919:Bradycardia / Q000139:chemically induced* / Q000503:physiopathology; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007022:Hypotension / Q000139:chemically induced* / Q000503:physiopathology; D008875:Middle Aged; D005996:Nitroglycerin / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D005996:Nitroglycerin
vernacular_title: Bradicardia severa e hipotensión arterial tras la administración de nitroglicerina sublingual.