title: Clock mutations alter developmental timing in Drosophila.
abstract: The developmental time of period mutants in Drosophila melanogaster was monitored under different environmental conditions. We observed that the pers mutants, which have short 19 h circadian cycles, develop faster from eggs to adult than the wild-type: perL mutants, which have long 28 h circadian rhythms, complete development more slowly than the wild-type. These results suggest that endogenous timers may be involved in regulating the development time of D. melanogaster.
authors.affiliation: Department of Genetics, University of Leicester, U.K.
authors.forename: C P
authors.initials: CP
authors.lastname: Kyriacou
authors.forename: M
authors.initials: M
authors.lastname: Oldroyd
authors.forename: J
authors.initials: J
authors.lastname: Wood
authors.forename: M
authors.initials: M
authors.lastname: Sharp
authors.forename: M
authors.initials: M
authors.lastname: Hill
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D001683:Biological Clocks; D004331:Drosophila melanogaster / Q000235:genetics* / Q000254:growth & development; D007814:Larva / Q000235:genetics / Q000502:physiology; D009154:Mutation; D010063:Ovum / Q000502:physiology; D013997:Time Factors