Group A variants defined with a monoclonal anti-A reagent.
Unusual serologic findings mimicking the B(A) phenomenon were noted in two group B blood donors using blended murine monoclonal anti-A reagent. With additional studies, including a binding experiment using affinity chromatography, the presence of aberrant group A activities was confirmed. This observation suggests that persons with atypical B(A) phenotype may warrant further investigation to delineate the ABO blood group.
Lau
P
P
American Red Cross Blood Services, Northwest Ohio Region, Toledo.
Sererat
S
S
Beatty
J
J
Oilschlager
R
R
Kini
J
J
D000017:ABO Blood-Group System / Q000235:genetics* / Q000276:immunology; D000328:Adult; D000911:Antibodies, Monoclonal; D001782:Blood Donors; D001788:Blood Grouping and Crossmatching / Q000379:methods*; D002846:Chromatography, Affinity; D005700:Galactosyltransferases / Q000097:blood; D014644:Genetic Variation; D006386:Hemagglutination Tests; D006801:Humans; D007202:Indicators and Reagents; D008297:Male; D017350:N-Acetylgalactosaminyltransferases
D000017:ABO Blood-Group System; D000911:Antibodies, Monoclonal; D007202:Indicators and Reagents; D005700:Galactosyltransferases; D017350:N-Acetylgalactosaminyltransferases; C003742:UDPgalactosamine-galactose acetylgalactosaminyltransferase