Long-term medical management of aldosterone-producing adenoma.
This case of Conn's syndrome demonstrates long-term (seven years) efficacy of triamterene-thiazide therapy in controlling both hypertension and hypokalemia. Studies done before the adrenal tumor was removed surgically showed that the tumor had increased in size and function since the first studies were done before triamterene-thiazide therapy. The resolution of hypertension after nine years of hyperaldosteronism suggests that surgery is effective even after chronic hyperaldosteronism has been present for some time.
Bornemann
M
M
Department of Medicine, Tripler Army Medical Center, Honolulu, Hawaii 96859-5000.
D000236:Adenoma / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism / Q000601:surgery; D000310:Adrenal Gland Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism / Q000601:surgery; D000450:Aldosterone / Q000378:metabolism*; D001581:Benzothiadiazines; D003131:Combined Modality Therapy; D004232:Diuretics; D004338:Drug Combinations; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000150:complications / Q000209:etiology*; D006973:Hypertension / Q000188:drug therapy / Q000209:etiology; D008134:Long-Term Care; D008875:Middle Aged; D049993:Sodium Chloride Symporter Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D014223:Triamterene / Q000008:administration & dosage / Q000627:therapeutic use*
D001581:Benzothiadiazines; D004232:Diuretics; D004338:Drug Combinations; D049993:Sodium Chloride Symporter Inhibitors; D000450:Aldosterone; D014223:Triamterene