title: [Analysis of the frequency of spontaneous and induced autosomal recessive lethal mutations in the oogenesis of the radiosensitive mutant rad(2)201G1 of Drosophila melanogaster].
abstract: The frequency of spontaneous and gamma-ray induced autosomal recessive lethals has been studied in chromosomes 2 and 3 at different stages of Drosophila melanogaster radiosensitive mutant rad (2) 201G1 oogenesis. The frequency of spontaneous lethals in radiosensitive mutant was higher by the order of magnitude as compared with wild-type flies (9.3 and 0.6%, respectively). Germ cells of radiosensitive mutant were of high mutability at all stages of oogenesis studied. The irradiation of flies by 1.29 x 10(-1) Kl/kg results in decrease of lethals frequency in radiosensitive mutant as compared with the spontaneous level, whereas under irradiation by 7.74 x 10(-2) Kl/kg no change in mutability was revealed.
authors.forename: V G
authors.initials: VG
authors.lastname: Zaĭnullin
authors.forename: K V
authors.initials: KV
authors.lastname: Vatti
authors.forename: V S
authors.initials: VS
authors.lastname: Mikheev
mesh_terms: D000818:Animals; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D005720:Gamma Rays; D005787:Gene Frequency; D005804:Genes, Lethal; D005808:Genes, Recessive; D009154:Mutation; D009866:Oogenesis; D011836:Radiation Tolerance / Q000235:genetics*
vernacular_title: Analiz chastoty spontannykh i indutsirovannykh autosomnykh retsessivnykh letal'nykh mutatsiĭ v oogeneze radiochuvstvitel'nogo mutanta rad(2)201G1 Drosophila melanogaster.