title: [Value of squamous cell epithelial-associated (SCC-) antigens in early diagnosis of oral carcinoma].
abstract: The diagnostic value of plasma concentration of the squamous cell carcinoma antigen was examined in 75 cases of pretherapeutic squamous cell carcinoma of the oral cavity. A pathologic plasma level was found in 32% of the tumour patients at time of diagnosis. The incidence of elevated SCC- values was inversely correlated to the tumour grading. A direct correlation of the sonographically measured total tumour volume was seen. As predominantly more extended tumours show pathologic values, SCC-Antigen is not a marker for the screening in the diagnosis of the early cancer of oral cavity. That emphasizes the importance of the precise clinical examination of each patient. In cases of elevated pretherapeutic values SCC-Antigen is very useful for therapy--monitoring and follow-up.
authors.affiliation: Klinik und Poliklinik für Mund-Kiefer-Gesichtschirurgie, Heidelberg.
authors.forename: J
authors.initials: J
authors.lastname: Zöller
authors.forename: U
authors.initials: U
authors.lastname: Mende
authors.forename: W
authors.initials: W
authors.lastname: Fiehn
mesh_terms: D000951:Antigens, Neoplasm / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood*; D002294:Carcinoma, Squamous Cell / Q000097:blood* / Q000175:diagnosis / Q000276:immunology; D006801:Humans; D009062:Mouth Neoplasms / Q000097:blood* / Q000175:diagnosis / Q000276:immunology
chemical_list: D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor
vernacular_title: Die Bedeutung des plattenepithel-assoziierten (SCC-) Antigens in der Früherkennung des Mundhöhlenkarzinoms.