title: Preparation, 252Cf-plasma-desorption mass spectrometry and radiometal exchange of the Pb2+ and Bi3+ complexes of a hexalactam macrocycle.
abstract: A macrocyclic tricatechol hexalactam ligand readily forms complexes with Pb2+ and Bi3+ ions. Solid samples were isolated and characterized by 252Cf-plasma-desorption mass spectroscopy (252Cf-PDMS). Radioactive metal exchange studies employing 210Pb and 210Bi showed the compounds to be kinetically inert to exchange. The feasibility of using an available source of 203Pb, a potential imaging agent, with this class of compound was shown by synthesis of the labelled hexalactam complex.
authors.affiliation: Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.
authors.forename: M
authors.initials: M
authors.lastname: Magerstadt
authors.forename: O A
authors.initials: OA
authors.lastname: Gansow
authors.forename: L K
authors.initials: LK
authors.lastname: Pannell
authors.forename: F
authors.initials: F
authors.lastname: Vogtele
authors.forename: W
authors.initials: W
authors.lastname: Kiggen
mesh_terms: D001729:Bismuth / Q000032:analysis; D007769:Lactams / Q000032:analysis; D007854:Lead / Q000032:analysis; D013058:Mass Spectrometry
chemical_list: D007769:Lactams; C065268:tricatechol hexalactam-bismuth(III) complex; C065267:tricatechol hexalactam-lead(II) complex; D007854:Lead; D001729:Bismuth