Lack of interference by sorbitol with aminopyrine breath test.
The effect of sorbitol on the aminopyrine breath test was investigated in 13 patients with various liver diseases given a bolus dose of sorbitol 20 mg.kg-1 i.v. 30 min after 14C-aminopyrine and 13 patients without the sorbitol bolus who also underwent an aminopyrine breath test. The time course of 14CO2 exhalation after the bolus of sorbitol did not differ from that in the control group.
Ramin
V C
VC
Division of Clinical Pharmacology, University of Göttingen, Federal Republic of Germany.
Bircher
J
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D000632:Aminopyrine / Q000008:administration & dosage* / Q000378:metabolism*; D001944:Breath Tests; D002245:Carbon Dioxide / Q000032:analysis; D016022:Case-Control Studies; D004347:Drug Interactions; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D013012:Sorbitol / Q000008:administration & dosage / Q000378:metabolism* / Q000494:pharmacology; D013997:Time Factors
D000632:Aminopyrine; D002245:Carbon Dioxide; D013012:Sorbitol