[Penicillin-binding proteins of various strains of Lactobacillus].
Sensitivity of different species of Lactobacillus i.e. L. casei, L. plantarum, L. acidophillus, L. buchneri, L. jugurti and others to penicillins and cephalosporins of various generations was studied. Penicillin binding proteins (PBPs) of the Lactobacillus species were specified. It was shown that the number of PBPs depended on the Lactobacillus species. L. casei had the least number of PBPs (4) and L. brevis had the highest number of PBPs (11). Competition of 14C-benzylpenicillin with ampicillin, cefotaxime, ceftizoxime and cefoperazone for binding to separate PBPs in three strains of different Lactobacillus species was investigated.
Griaznova
N S
NS
Subbotina
N A
NA
Beliavskaia
I V
IV
Taisova
A S
AS
Afonin
V I
VI
Tiurin
M V
MV
Shenderov
B A
BA
Sazykina
Iu O
IuO
Navashin
S M
SM
D000667:Ampicillin / Q000378:metabolism; D001667:Binding, Competitive; D002352:Carrier Proteins / Q000378:metabolism*; D002511:Cephalosporins / Q000378:metabolism; D003470:Culture Media; D004352:Drug Resistance, Microbial; D066298:In Vitro Techniques; D007778:Lactobacillus / Q000187:drug effects / Q000378:metabolism*; D007779:Lactobacillus acidophilus / Q000378:metabolism; D007780:Lacticaseibacillus casei / Q000378:metabolism; D010400:Penicillin G / Q000378:metabolism*; D010403:Penicillin Resistance; D011485:Protein Binding
D002352:Carrier Proteins; D002511:Cephalosporins; D003470:Culture Media; D000667:Ampicillin; D010400:Penicillin G
Penitsillinsviazyvaiushchie belki nekotorykh vidov laktobatsill.