[The effect of thyroliberin on the blood level of gonadotropins and sex steroids in women suffering from Itsenko-Cushing disease].
The authors examined the level of gonadotropin (lutropin, follitropin) and sex steroids (estradiol, progesteron, testosterone) before and after administration of thyroliberin in 10 healthy women and 15 females suffering of Itsenko-Cushing disease. It was established that both the healthy and patients with Itsenko-Cushing disease did not reveal any significant changes in the level of lutropin, follitropin, estradiol, progesteron, testosteron after administration of thyroliberin within 2 hours of the examination. Data indicate absence of paradoxic response of gonadotropins and cells secreting sex steroids in Itsenko-Cushing disease.
Manusharova
R A
RA
Bezverkhaia
T P
TP
D000328:Adult; D002908:Chronic Disease; D003480:Cushing Syndrome / Q000097:blood / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006065:Gonadotropins, Pituitary / Q000097:blood*; D006801:Humans; D013973:Thyrotropin-Releasing Hormone / Q000627:therapeutic use*; D013997:Time Factors
D012739:Gonadal Steroid Hormones; D006065:Gonadotropins, Pituitary; D013973:Thyrotropin-Releasing Hormone
Vliianie tiroliberina na uroven' gonadotropinov i polovykh steroidov v krovi zhenshchin, stradaiushchikh bolezn'iu Itsenko--Kushinga.