Histiocytosis X: successful treatment with recombinant interferon-alpha A.
Two patients with disseminated histiocytosis X were treated with intramuscular injections of recombinant interferon alpha A. The bone, skin and visceral lesions of these patients diminished rapidly. Significant sclerosis and recalcification of bone were observed. From our limited but positive experience, it would be justified to consider the use of interferon in patients with disseminated histiocytosis X.
Sato
Y
Y
Department of Pediatrics, School of Medicine, University of Hirosaki, Japan.
Ikeda
Y
Y
Ito
E
E
Miyano
T
T
Kawauchi
K
K
Yokoyama
M
M
Kamata
Y
Y
D006646:Histiocytosis, Langerhans-Cell / Q000628:therapy*; D006801:Humans; D007223:Infant; D007370:Interferon Type I / Q000627:therapeutic use*; D008297:Male; D011994:Recombinant Proteins
D007370:Interferon Type I; D011994:Recombinant Proteins