title: Efficient use of endpoints in clinical trials: a clinical perspective.
abstract: Efficiencies in the use of endpoints in clinical trials are hard won, not easy. They depend upon the shifting of study resources among clinical centres and central units, as well as between numbers of participants and the costs of the endpoint measurement. Costs of endpoint measurement and evaluation do not tell the whole story; nor do costs multiplied by the total number of patients to be recruited; other costs generated by a particular endpoint must also be taken into account. Each clinical trial must be considered separately for the efficient use of endpoints.
authors.affiliation: Maryland Medical Research Institute, Baltimore 21210.
authors.forename: M L
authors.initials: ML
authors.lastname: Terrin
mesh_terms: D003363:Cost Control / Q000379:methods; D003362:Cost-Benefit Analysis; D003365:Costs and Cost Analysis; D003625:Data Collection / Q000379:methods; D004526:Efficiency; D016032:Randomized Controlled Trials as Topic / Q000191:economics* / Q000379:methods; D012107:Research Design / Q000191:economics