title: Recognition of novel glycolipid antigens from smooth variants of Mycobacterium tuberculosis.
abstract: A major polar and three minor slightly less polar glycolipids were identified in extracts of two smooth (Canetti) strains of Mycobacterium tuberculosis. Immunostaining on thin-layer chromatograms and enzyme-linked immunosorbent assay (ELISA) of purified lipids demonstrated that the major and the two most polar of the minor glycolipids are potent antigens, reacting with homologous antisera and also with that raised against the type strain (H37Rv).
authors.affiliation: Department of Chemistry, The University, Newcastle-upon-Tyne, UK.
authors.forename: D E
authors.initials: DE
authors.lastname: Minnikin
authors.forename: M
authors.initials: M
authors.lastname: Ridell
authors.forename: R C
authors.initials: RC
authors.lastname: Bolton
authors.forename: M
authors.initials: M
authors.lastname: Magnusson
mesh_terms: D000942:Antigens, Bacterial / Q000302:isolation & purification*; D002855:Chromatography, Thin Layer; D006017:Glycolipids / Q000276:immunology* / Q000302:isolation & purification; D009169:Mycobacterium tuberculosis / Q000276:immunology*; D013045:Species Specificity
chemical_list: D000942:Antigens, Bacterial; D006017:Glycolipids