title: [Regulation of thyroid hormones of the interaction of mitochondria with low-molecular weight cytoplasmic mediators, induced by phosphate- dependent transport of K+ and H+ ions through the mitochondrial inner membrane].
abstract: In vivo thyroid hormones control the binding to mitochondria of low molecular weight water-soluble cytoplasmic mediators that are capable to induce oxidative phosphorylation uncoupling, by increasing the sensitivity of mitochondria to the effects of these mediators. In hyperthyroid rat liver mitochondria cytoplasmic mediators stimulate the phosphate-dependent transport of K+ and H+ in a greater degree than in liver mitochondria of control rats. The increase in the oxidative phosphorylation uncoupling by cytoplasmic mediators is one of mechanisms of thermogenesis stimulation by thyroid hormones.
authors.forename: M Kh
authors.initials: MKh
authors.lastname: Gaĭnutdinov
authors.forename: V V
authors.initials: VV
authors.lastname: Konov
authors.forename: R N
authors.initials: RN
authors.lastname: Ishmukhamedov
authors.forename: T N
authors.initials: TN
authors.lastname: Zakharova
authors.forename: M A
authors.initials: MA
authors.lastname: Khalilova
authors.forename: Z A
authors.initials: ZA
authors.lastname: Mamatova
authors.forename: M I
authors.initials: MI
authors.lastname: Asrarov
authors.forename: S I
authors.initials: SI
authors.lastname: Mirmakhmudova
mesh_terms: D000818:Animals; D001692:Biological Transport; D002462:Cell Membrane / Q000378:metabolism; D003593:Cytoplasm / Q000737:chemistry; D006859:Hydrogen / Q000378:metabolism*; D008297:Male; D008930:Mitochondria, Liver / Q000378:metabolism*; D008970:Molecular Weight; D010085:Oxidative Phosphorylation; D010710:Phosphates / Q000378:metabolism; D011188:Potassium / Q000378:metabolism*; D051381:Rats; D013963:Thyroid Hormones / Q000502:physiology*
chemical_list: D010710:Phosphates; D013963:Thyroid Hormones; D006859:Hydrogen; D011188:Potassium
vernacular_title: Reguliatsiia tireoidnymi gormonami vzaimodeĭstviia mitokhondriĭ s nizkomolekuliarnymi tsitoplazmaticheskimi mediatorami, indutsiruiushchimi fosfatzavisimyĭ transport ionov K+ i H+ cherez membranu mitokhondriĭ.