title: [Possibilities of chemical detoxification of aflatoxin].
abstract: The efficacy of inactivation of aflatoxin B1 (AFB1, 2.0-2.6 mg per kg) in aqueous medium in exposure to 21 chemicals or their mixtures for two hours and for two days was evaluated by measuring the extracts on a fluorescence spectrophotometer. Reduction to less than 10% of the original AFB1 content within two hours was recorded when the medium contained 1.5% potassium permanganate, 2.5 and 5% Chloramin B (Lachema) or soda, and when there was 5% ammonia heated to 60 degrees C, 5% sodium hydroxide, potassium hydroxide or calcium hydroxide, or 50% chromosulphuric acid. AFB1 and other fluorescing metabolites were completely destroyed after two days of exposure to a 5% ammonia solution heated to 60 degrees C for the first two hours and after two days of exposure to 5% Chloramin B, 5% soda, 5% calcium hydroxide, 50% chromosulphuric acid, and mixture of 2.5% sulphuric acid with 0.75% potassium permanganage. Acids used alone had the lowest effectiveness.
authors.affiliation: Výzkumný ústav veterinárního lékarství, Brno.
authors.forename: M
authors.initials: M
authors.lastname: Dvorák
mesh_terms: D016604:Aflatoxin B1; D000348:Aflatoxins / Q000032:analysis; D000821:Animal Feed / Q000032:analysis; D002273:Carcinogens / Q000032:analysis; D003666:Decontamination / Q000379:methods; D013050:Spectrometry, Fluorescence
chemical_list: D000348:Aflatoxins; D002273:Carcinogens; D016604:Aflatoxin B1
vernacular_title: Moznosti chemické detoxikace aflatoxinů.