title: Efficacy of combined metronidazole and triple tetracycline therapy in the treatment of non-gonococcal urethritis.
abstract: In a double-blind placebo-controlled trial using triple tetracycline (Deteclo, Lederle) 300 mg twice daily for two weeks in conjunction with metronidazole (Flagyl, May & Baker) 400 mg or matching placebo twice daily for seven days, it was shown that the addition of anti-anaerobic therapy did not significantly affect the number of cases of persistent urethritis or the relapse of patients with non-gonococcal urethritis (NGU).
authors.affiliation: Department of Genitourinary Medicine, Royal Hallamshire Hospital, Sheffield, UK.
authors.forename: P D
authors.initials: PD
authors.lastname: Woolley
authors.forename: G R
authors.initials: GR
authors.lastname: Kinghorn
authors.forename: M D
authors.initials: MD
authors.lastname: Talbot
authors.forename: B I
authors.initials: BI
authors.lastname: Duerden
mesh_terms: D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use*; D012008:Recurrence; D013754:Tetracyclines / Q000627:therapeutic use*; D014526:Urethritis / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D013754:Tetracyclines; D008795:Metronidazole