title: Biosynthesis of biotin-vitamers by family Enterobacteriaceae.
abstract: The biosynthesis of biotin-vitamers from various carbon sources by the members of the Enterobacteriaceae as one of the groups of intestinal bacteria was investigated. The biotin-vitamers synthesized in each case included one or more of dethiobiotin (main product), 7-keto-8-aminopelargonic acid, and biotin. True biotin was shown to be synthesized under aerobic conditions but not under anaerobic conditions by each of several strains belonging to one of the genera, Erwinia, Escherichia, Proteus, and Serratia, and using culture media containing one of galactose, peptone, Polypepton, or casamino acid. In addition, a biotin precursor, pimelic acid, was also synthesized by several bacteria utilizing carbon sources such as maltose, mannose, galactose, peptone, or casamino acid.
authors.affiliation: Department of Food Science, Faculty of Home Economics, Mukogawa Women's University, Nishinomiya, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Ohsugi
authors.forename: Y
authors.initials: Y
authors.lastname: Imanishi
authors.forename: T
authors.initials: T
authors.lastname: Teraoka
authors.forename: K
authors.initials: K
authors.lastname: Nishimura
authors.forename: S
authors.initials: S
authors.lastname: Nakao
mesh_terms: D001710:Biotin / Q000096:biosynthesis*; D002244:Carbon / Q000378:metabolism; D004755:Enterobacteriaceae / Q000254:growth & development / Q000378:metabolism*; D010867:Pimelic Acids / Q000378:metabolism
chemical_list: D010867:Pimelic Acids; D001710:Biotin; D002244:Carbon