Local application of EMLA and glyceryl trinitrate ointment before venepuncture.
One hundred unpremedicated fit day surgery patients aged between 27 and 68 years were allocated randomly into one of four groups and EMLA, glyceryl trinitrate, EMLA and glyceryl trinitrate or a placebo ointment was applied to the dorsum of a hand. The pain and ease of venepuncture were determined at induction of anaesthesia 60 minutes later. Pain scores were also reassessed 1-2 hours after operation. Lower pain scores and easier venepuncture occurred when EMLA and glyceryl trinitrate ointment was applied to the dorsum of the hand.
Gunawardene
R D
RD
Department of Anaesthesia, Northwick Park Hospital, Harrow, Middlesex.
Davenport
H T
HT
D000279:Administration, Cutaneous; D000328:Adult; D000368:Aged; D000771:Anesthesia, Intravenous / Q000009:adverse effects; D000772:Anesthesia, Local; D000779:Anesthetics, Local / Q000008:administration & dosage; D004311:Double-Blind Method; D004338:Drug Combinations / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage; D000077442:Lidocaine, Prilocaine Drug Combination; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000008:administration & dosage; D010146:Pain / Q000517:prevention & control; D011318:Prilocaine / Q000008:administration & dosage; D011897:Random Allocation
D000779:Anesthetics, Local; D004338:Drug Combinations; D000077442:Lidocaine, Prilocaine Drug Combination; D011318:Prilocaine; D008012:Lidocaine; D005996:Nitroglycerin