HLA, GM, KM, and Diego blood group typing of Chippewa Indians.
This is the first report characterizing HLA antigen distribution in North American Indians of the Chippewa tribe. One hundred seventy-four Chippewa from Minnesota underwent HLA-A,B,C,DR, and DQ typing in a search for a single unrelated bone marrow donor. The high matching rate of this successful search is attributed to homozygosity and the extreme frequency of certain antigens in this small ethnic community. It is emphasized that smaller donor pools are required in searches within a minority population. GM and KM allotype typing as well as blood group Diego typing show patterns similar to those reported in other North American Indian groups.
Lee
T D
TD
American Red Cross Blood Services, Holland Laboratory, Rockville, Maryland.
Zhao
T M
TM
Chow
M P
MP
Lee
G
G
D001789:Blood Group Antigens; D001788:Blood Grouping and Crossmatching; D006680:HLA Antigens / Q000032:analysis*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007143:Immunoglobulin Heavy Chains / Q000032:analysis*; D007145:Immunoglobulin kappa-Chains / Q000032:analysis*; D007198:Indians, North American; D010641:Phenotype
D001789:Blood Group Antigens; D006680:HLA Antigens; D007074:Immunoglobulin G; D007143:Immunoglobulin Heavy Chains; D007145:Immunoglobulin kappa-Chains