title: Effect of ketotifen on the ultrastructure of the erythrocytic stages of Plasmodium yoelii.
abstract: The effect on the morphology of Plasmodium yoelii of ketotifen treatment was different from that of chloroquine and other antimalarial drugs. Following administration of a low dosage of ketotifen, the parasite first developed a multilamellate pellicular complex which resembled a medullary sheath and then developed vacuoles and cavitations. The development of large multilamellate whorls consisting of a pellicular structure enclosing cytoplasm was the typical change which occurred.
authors.affiliation: Department of Biology, East China Normal University, Shanghai.
authors.forename: H M
authors.initials: HM
authors.lastname: Cao
authors.forename: X Q
authors.initials: XQ
authors.lastname: Pan
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004912:Erythrocytes; D007665:Ketotifen / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D008288:Malaria / Q000188:drug therapy*; D051379:Mice; D010967:Plasmodium yoelii / Q000187:drug effects* / Q000648:ultrastructure
chemical_list: D007665:Ketotifen