Emerging applications of the methylotrophic yeasts.
The use of methylotrophic yeasts for the production of single-cell-protein (SCP), alcohol oxidase and fine chemicals has been proposed. Fermentation technology developed for the growth of these yeasts on methanol at high cell densities has been commercialized. However, it is the production of heterologous recombinant proteins by Pichia pastoris that is emerging as the most significant application of the methylotrophic yeasts.
Wegner
G H
GH
Research and Development, Phillips Petroleum Company, Bartlesville, OK 74004.
D000429:Alcohol Oxidoreductases / Q000378:metabolism*; D004044:Dietary Proteins / Q000378:metabolism*; D005285:Fermentation; D005656:Fungal Proteins / Q000235:genetics / Q000378:metabolism*; D015870:Gene Expression; D000432:Methanol / Q000378:metabolism*; D011994:Recombinant Proteins / Q000235:genetics / Q000378:metabolism; D015003:Yeasts / Q000235:genetics / Q000378:metabolism*
D004044:Dietary Proteins; D005656:Fungal Proteins; D011994:Recombinant Proteins; C012551:single cell proteins; D000429:Alcohol Oxidoreductases; C019643:alcohol oxidase; D000432:Methanol