A combined adenine-phosphate effect inhibits the reactivation of eye lens epithelial cells in primary culture.
A low molecular weight component from serum, which in combination with adenine strongly retards the spreading of lens epithelial cells in primary culture, could be identified as inorganic phosphate. The possible mechanism of the combined action of adenine and phosphate is discussed.
Glaesser
D
D
Institute of Biochemistry, Martin Luther University, Halle, Salle.
Iwig
M
M
D000225:Adenine / Q000494:pharmacology*; D000818:Animals; D002417:Cattle; D002478:Cells, Cultured; D002850:Chromatography, Gel; D002855:Chromatography, Thin Layer; D004338:Drug Combinations; D004848:Epithelium / Q000187:drug effects / Q000648:ultrastructure; D007908:Lens, Crystalline / Q000187:drug effects* / Q000648:ultrastructure; D010710:Phosphates / Q000494:pharmacology*; D014961:X-Ray Diffraction
D004338:Drug Combinations; D010710:Phosphates; D000225:Adenine