title: Local application of EMLA and glyceryl trinitrate ointment before venepuncture.
abstract: One hundred unpremedicated fit day surgery patients aged between 27 and 68 years were allocated randomly into one of four groups and EMLA, glyceryl trinitrate, EMLA and glyceryl trinitrate or a placebo ointment was applied to the dorsum of a hand. The pain and ease of venepuncture were determined at induction of anaesthesia 60 minutes later. Pain scores were also reassessed 1-2 hours after operation. Lower pain scores and easier venepuncture occurred when EMLA and glyceryl trinitrate ointment was applied to the dorsum of the hand.
authors.affiliation: Department of Anaesthesia, Northwick Park Hospital, Harrow, Middlesex.
authors.forename: R D
authors.initials: RD
authors.lastname: Gunawardene
authors.forename: H T
authors.initials: HT
authors.lastname: Davenport
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D000368:Aged; D000771:Anesthesia, Intravenous / Q000009:adverse effects; D000772:Anesthesia, Local; D000779:Anesthetics, Local / Q000008:administration & dosage; D004311:Double-Blind Method; D004338:Drug Combinations / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage; D000077442:Lidocaine, Prilocaine Drug Combination; D008297:Male; D008875:Middle Aged; D005996:Nitroglycerin / Q000008:administration & dosage; D010146:Pain / Q000517:prevention & control; D011318:Prilocaine / Q000008:administration & dosage; D011897:Random Allocation
chemical_list: D000779:Anesthetics, Local; D004338:Drug Combinations; D000077442:Lidocaine, Prilocaine Drug Combination; D011318:Prilocaine; D008012:Lidocaine; D005996:Nitroglycerin