[A case of B-cell non-Hodgkin's lymphoma with prominent splenomegaly and high serum titer of cold agglutinin].
The case of 37-year-old male with non-Hodgkin's lymphoma with prominent splenomegaly is presented. The spleen that was removed for analysis had a weight of 2690 grams and a section inspection revealed multiple, whitish, small nodules that were disseminated throughout the entire spleen. It was microscopically demonstrated to be a B-Cell lymphoma of diffuse, medium-sized cells and an IgM.kappa Type. This case also was complicated by a high serum titer of cold agglutinin that was decreased by chemotherapy.
Fujise
K
K
1st Dept. of Int. Med., Jikei Univ. School of Med.
Yazawa
M
M
Hashimoto
N
N
Sujino
H
H
Yanagisawa
T
T
Kawase
H
H
Ishihara
F
F
Kameda
H
H
Kuraishi
S
S
Kobayashi
S
S
D000328:Adult; D000373:Agglutinins / Q000378:metabolism*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001402:B-Lymphocytes; D003131:Combined Modality Therapy; D003450:Cryoglobulins; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D007075:Immunoglobulin M / Q000378:metabolism; D007145:Immunoglobulin kappa-Chains / Q000378:metabolism; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000276:immunology* / Q000628:therapy; D008297:Male; D011241:Prednisone / Q000008:administration & dosage; D013156:Splenectomy; D013163:Splenomegaly / Q000209:etiology*; D014750:Vincristine / Q000008:administration & dosage
D000373:Agglutinins; D003450:Cryoglobulins; D007075:Immunoglobulin M; D007145:Immunoglobulin kappa-Chains; C029443:cold agglutinins; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone