title: Multiple myeloma associated with amyloidosis and t(1;20)(q21;q11) translocation.
abstract: A 59-year-old woman with nephrotic syndrome was diagnosed as having primary amyloidosis based on the detection of amyloid deposition (AL-protein) in the esophagus and kidneys. Bone marrow aspirate showed plasmocytic proliferation, leading to a diagnosis of multiple myeloma (IgG lambda-type). In addition, a very rare translocation t(1; 20) (q21; q11) was seen by chromosomal analysis of both the bone marrow and peripheral blood.
authors.affiliation: Second Department of Internal Medicine, Iwate Medical University School of Medicine, Morioka.
authors.forename: K
authors.initials: K
authors.lastname: Otokida
authors.forename: H
authors.initials: H
authors.lastname: Yoshida
authors.forename: Y
authors.initials: Y
authors.lastname: Mizunuma
authors.forename: M
authors.initials: M
authors.lastname: Yamada
authors.forename: K
authors.initials: K
authors.lastname: Hiramori
mesh_terms: D000686:Amyloidosis / Q000150:complications / Q000235:genetics*; D002871:Chromosome Banding; D002878:Chromosomes, Human, Pair 1; D002890:Chromosomes, Human, Pair 20; D005260:Female; D006801:Humans; D007621:Karyotyping; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications / Q000235:genetics*; D014178:Translocation, Genetic