Characteristics of serogroup A Neisseria meningitidis responsible for an epidemic in Ethiopia, 1988-89.
In September 1988, an epidemic of meningococcal disease started in Ethiopia. 21 Neisseria meningitidis isolates recovered from patients in Addis Ababa and towns 200 km south of the capital were characterized by serogrouping, serotyping, testing of susceptibility to antibiotics, restriction endonuclease fingerprinting, and multilocus enzyme electrophoresis. The 21 isolates were essentially homogeneous for all properties tested and belonged to clone III-1 of serogroup A N. meningitidis, which was also responsible for the epidemics in Saudi Arabia in 1987 and in Sudan and Chad in 1988.
Haimanot
R T
RT
Department of Medicine, Faculty of Medicine, Addis Ababa, Ethiopia.
Caugant
D A
DA
Fekadu
D
D
Bjune
G
G
Belete
B
B
Frøholm
L O
LO
Høiby
E A
EA
Rosenqvist
E
E
Selander
R K
RK
Bjorvatn
B
B
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004196:Disease Outbreaks; D005002:Ethiopia / Q000453:epidemiology; D006801:Humans; D008585:Meningitis, Meningococcal / Q000453:epidemiology / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009345:Neisseria meningitidis / Q000145:classification* / Q000187:drug effects / Q000302:isolation & purification; D015183:Restriction Mapping; D012703:Serotyping; D013997:Time Factors
D000900:Anti-Bacterial Agents