Once-daily ethosuximide in the treatment of absence epilepsy.
Once-daily ethosuximide was used to treat 10 consecutive children with typical absence seizures. Three patients had gastrointestinal side effects which resolved when the same total daily dose was divided into 2 doses. Two other patients continued to have seizures on ethosuximide, whether given once or twice daily. Five patients had complete seizure control without adverse effects on once-daily ethosuximide.
Dooley
J M
JM
Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada.
Camfield
P R
PR
Camfield
C S
CS
Fraser
A D
AD
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D004832:Epilepsy, Absence / Q000188:drug therapy*; D005013:Ethosuximide / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006801:Humans; D009325:Nausea / Q000139:chemically induced
D005013:Ethosuximide