title: [Obytin in the treatment of superficial skin mycoses].
abstract: Obytin (1% Cyclopyroxolamine) in the form of cream, a preparation of the firm Jugoremedija/Hoechst, was applied in the treatment of 33 patients with dermatophytic skin infections. The diseases were most frequently located in the intertriginous areas 19 (57%), somewhat less frequently on nude places of the skin 9 (27%), and on the hands and feet 5 (16%). The cream was applied twice daily for 28 days. Acute clinical symptoms of the disease disappeared rapidly under the influence of the preparation and disappeared completely after three weeks of treatment in 32 patients (97%); and four weeks after start of therapy mycology tests were negative in the same number of cases. Only 3% of patients had no evident changes during therapy. Obytin is one of the new topical antifungal agents with a wide spectrum of action and it can be used in all types of superficial dermatomycoses as well as in some bacterial infections. It is characterized by rapid onset of action. Side effects of local or systemic nature (irritative, alergic or toxic) had not been registered.
authors.affiliation: Dermatoveneroloska klinika Univerzitetsko-klinickog centra, Beograd.
authors.forename: V
authors.initials: V
authors.lastname: Radović-Kovacević
authors.forename: R
authors.initials: R
authors.lastname: Ratković
authors.forename: A
authors.initials: A
authors.lastname: Milenković
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use*; D000077768:Ciclopirox; D003881:Dermatomycoses / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011728:Pyridones / Q000627:therapeutic use*
chemical_list: D000935:Antifungal Agents; D011728:Pyridones; D000077768:Ciclopirox
vernacular_title: Obytin u lecenju povrsnih mikoza koze.