title: Cyclosporine A prolonged survival time of parathyroid gland allograft in rats.
abstract: We divided the experimental animals into three groups. In the first group, only cyclosporine solvent containing no cyclosporine was given to rats. In the second group, cyclosporine A was given intraperitoneally from the 1st to the 5th days after transplantation at a daily dosage of 2 mg/100 g BW. In the third group, besides the first courses of cyclosporine A treatment as in group II, second and third courses were given on the 30th to 34th and 60th to 64th days after transplantation. Our results show that a relatively large dose given in a short course together with intermittent enhancement treatment proves much more effective than a short course without enhancement treatment.
authors.affiliation: PUMC Hospital, CAMS, Beijing.
authors.forename: X
authors.initials: X
authors.lastname: He
authors.forename: Y
authors.initials: Y
authors.lastname: Zhu
mesh_terms: D000818:Animals; D002118:Calcium / Q000097:blood; D003524:Cyclosporins / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D006085:Graft Survival / Q000187:drug effects*; D008297:Male; D010280:Parathyroid Glands / Q000637:transplantation*; D016105:Parathyroidectomy; D051381:Rats; D011912:Rats, Inbred ACI; D011916:Rats, Inbred F344
chemical_list: D003524:Cyclosporins; D002118:Calcium