title: Molecular similarity of Drosophila melanogaster alcohol dehydrogenase thermostable alleles from populations on different continents.
abstract: Allele specific oligonucleotide probes have been used to show that DNA, amplified by the polymerase chain reaction, from eleven thermostable Adh alleles extracted from populations on different continents contains the triplet TCC, which distinguishes AdhFChD (Fast Chateau Douglas) from AdhF (Fast). The molecular similarity of Adh thermostable alleles suggests that they had a common origin, and it is argued that the mutation probably occurred in China where high frequencies of AdhFChD are found.
authors.affiliation: Molecular and Population Genetics Group, Research School of Biological Sciences, Australian National University, Canberra City.
authors.forename: J B
authors.initials: JB
authors.lastname: Gibson
authors.forename: D
authors.initials: D
authors.lastname: Reed
authors.forename: A V
authors.initials: AV
authors.lastname: Wilks
authors.forename: C S
authors.initials: CS
authors.lastname: Jiang
mesh_terms: D000426:Alcohol Dehydrogenase / Q000235:genetics*; D000483:Alleles; D000818:Animals; D001483:Base Sequence; D015139:Blotting, Southern; D003062:Codon; D004331:Drosophila melanogaster / Q000201:enzymology* / Q000235:genetics; D005784:Gene Amplification; D005828:Genetics, Population; D008969:Molecular Sequence Data; D015345:Oligonucleotide Probes; D016133:Polymerase Chain Reaction; D013696:Temperature
chemical_list: D003062:Codon; D015345:Oligonucleotide Probes; D000426:Alcohol Dehydrogenase