Reinfection of Somali children with Trichuris trichiura after chemotherapy: relevance of immunostimulation.
The intestinal helminth status of an age-stratified sample (6 to 20 years old) from a Somalian community has been assessed and the typical pattern of highly aggregated parasite distribution found. A reinfection study on a sample of 40 children (treated and untreated with a pentapeptide identical to the active site of the thymic hormone thymopoietin) seemed to indicate that immunological factors play a significant role in modulating the population dynamics of infection in endemic communities.
Shiddo
S
S
Faculty of Medicine, National University of Somalia, Mogadishu.
Ilardi
I
I
Mussa
C
C
Mohamud
M A
MA
Aceti
A
A
Leone
F
F
Sebastiani
A
A
Laghi
Amiconi
G
G
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005243:Feces / Q000469:parasitology; D006801:Humans; D007114:Immunization; D007156:Immunologic Memory; D007428:Intradermal Tests; D008297:Male; D008463:Mebendazole / Q000627:therapeutic use*; D010270:Parasite Egg Count; D012998:Somalia / Q000453:epidemiology; D016305:Thymopentin / Q000276:immunology; D014257:Trichuriasis / Q000188:drug therapy / Q000453:epidemiology / Q000276:immunology*
D008463:Mebendazole; D016305:Thymopentin