[Cholesterol and phospholipid levels in erythrocyte membrane of patients with blood lipid disorders and hypertension].
The aim of this paper was search for possible relationship between cholesterol and phospholipids in erythrocyte++ membrane and pathological entities i.e. hypertension and dyslipidemia. Both are the main risk factors of atherosclerosis and in both condition disturbances at the cell membrane level were detected. 124 persons (both men and women in a age group 20-59), employees of industrial enterprise were included into study. Standard questionnaire was performed as well as body weight and height, blood pressure, biochemical tests-lipids, cell membrane lipids serum and intracellular electrocytes as well as 24 h electrolyte urine excretion. The following findings were reported: cell membrane cholesterol concentration correlates with sex, age, body weight, systolic and diastolic blood pressure and triglycerydes HDL-cholesterol and serum phospholipids. The biggest influence on cholesterol concentration in cell membrane have the following factors: sex, age and serum triglycerides. The most important finding was that the lipid metabolism disturbances has impact on triglyceride elevation in serum and that arterial hypertension is connected with decreased cholesterol concentration in erytrocyte membrane.
Koblik
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Katedry Diagnostyki Biochemicznej i Kliniki Chorób Metabolicznych Akademii Medycznej w Krakowie.
D000328:Adult; D000367:Age Factors; D002784:Cholesterol / Q000097:blood*; D004910:Erythrocyte Membrane / Q000378:metabolism*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood*; D015228:Hypertriglyceridemia / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010743:Phospholipids / Q000097:blood*; D012737:Sex Factors
D010743:Phospholipids; D002784:Cholesterol
Stezenie cholesterolu i fosfolipidów w błonie komórkowej erytrocytów u osób z dyslipidemia i nadciśnieniem.