Genes involved in the development of the peripheral nervous system of Drosophila.
The development of the peripheral nervous system (PNS) requires the activity of a number of genes. The neurogenic and the proneural genes are necessary in the earliest phase; their mutations lead to hyperplasia and partial or total elimination of the PNS respectively. Some of these mutations also affect other developmental processes. Other mutations affect later events: cut transforms one type of sensory organ into another; numb alters the fate of the components of a single sensory organ. We will describe the effects of the best studied mutations on PNS development and discuss the possible role of the wild type genes.
Giangrande
A
A
Department of Zoology, University of Washington, Seattle 98195.
Palka
J
J
D000818:Animals; D002454:Cell Differentiation; D004330:Drosophila / Q000196:embryology / Q000235:genetics*; D005786:Gene Expression Regulation; D005796:Genes; D009024:Morphogenesis / Q000235:genetics; D010525:Peripheral Nerves / Q000196:embryology