Anti-sporozoite antibodies.
Development of anti-sporozoite vaccines based on CS (circumsporozoite) proteins has preceded a thorough understanding of the basic biology of sporozoite-hepatic cell interactions. Investigation of these interactions can only serve to further refine the existing sporozoite vaccines, as well as provide a rationale for the design of other vaccine candidates.
Hollingdale
M R
MR
Biomedical Research Institute, Rockville, MD 20852.
D000818:Animals; D000938:Antigen-Presenting Cells / Q000276:immunology; D002478:Cells, Cultured; D006801:Humans; D066298:In Vitro Techniques; D007728:Kupffer Cells / Q000276:immunology / Q000469:parasitology; D008099:Liver / Q000166:cytology / Q000469:parasitology*; D008288:Malaria / Q000469:parasitology / Q000517:prevention & control; D051379:Mice; D010961:Plasmodium / Q000276:immunology*; D051381:Rats; D014614:Vaccines, Synthetic / Q000627:therapeutic use
D014614:Vaccines, Synthetic