[Possible cardiotoxicity induced by orally administered fluoropyrimidines].
4 more cases of cardiotoxicity associated to 5-FU or oral fluoropirimidine (Ptorafur, UFT) in patients without previous heart disease (except in one case) are presented. The toxicity found was myocardial ischemia and EKG changes (in 3 patients) in patients whose enzymes were measured. The etiopathogenesis and features of this toxicity are discussed.
Camps
C
C
Servicio de Medicina Interna, Hospital General Universitario, Valencia.
Godes
M
M
Soler
J J
JJ
D000284:Administration, Oral; D000368:Aged; D005472:Fluorouracil / Q000008:administration & dosage / Q000009:adverse effects*; D006331:Heart Diseases / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D005641:Tegafur / Q000009:adverse effects*
D005641:Tegafur; D005472:Fluorouracil
Posible cardiotoxicidad inducida por fluoropirimidinas orales.