title: [Evoked auditory potentials in neonatal hyperbilirubinemia].
abstract: Neonatal hyperbilirubinemia (greater than 20 mg%) is an audiological risk factor. In order to check early detection of bilirubin-induced neurological damage in the brainstem, 19 newborns were enrolled in the present study. The criteria was a bilirubin level ranging from 12 to 20 mg%. A likely mechanism for bilirubin intoxication may be the slowing and desynchronization of acoustic stimuli in the brainstem. Auditory brainstem responses were performed using non filtered clicks at 100 dB SPL (peak equivalent). Absolute and interpeak latencies of waves I and V were measured and correlated to bilirubinemia upon acoustic stimulation and maximal bilirubinemia observed during neonatal observation. Significant correlations were noted between bilirubinemia and V or V-I latencies. No significant correlation was observed between bilirubinemia and wave I latencies. Similar results were obtained in a restricted group of term neonates with hyperbilirubinemia. It is, thus, concluded that hyperbilirubinemia affects the upper auditory pathways.
authors.affiliation: Divisione Otorinolaringoiatrica, Ospedale V. Monaldi di Napoli.
authors.forename: F
authors.initials: F
authors.lastname: Mosca
authors.forename: A
authors.initials: A
authors.lastname: Giustardi
authors.forename: F
authors.initials: F
authors.lastname: Orbinato
mesh_terms: D001306:Auditory Pathways; D001663:Bilirubin / Q000097:blood; D003638:Deafness / Q000209:etiology; D016057:Evoked Potentials, Auditory, Brain Stem; D006801:Humans; D007231:Infant, Newborn; D007567:Jaundice, Neonatal / Q000150:complications / Q000175:diagnosis*; D012307:Risk Factors
chemical_list: D001663:Bilirubin
vernacular_title: I potenziali evocati uditivi nell'iperbilirubinemia neonatale.