A review of the effects of glutamine-enriched diets on experimentally induced enterocolitis.
Studies in animal models of enterocolitis have failed to confirm the purported metabolic and functional benefits of bowel rest induced by use of an elemental diet. Recent reports have demonstrated that glutamine-supplemented diets ameliorate or reverse many of the adverse effects of experimentally induced enterocolitis. Human studies are needed to confirm these findings.
Rombeau
J L
JL
Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia.
D000818:Animals; D006224:Cricetinae; D004247:DNA / Q000032:analysis / Q000378:metabolism; D004195:Disease Models, Animal; D004750:Enteral Nutrition; D004760:Enterocolitis / Q000139:chemically induced / Q000473:pathology / Q000628:therapy*; D005472:Fluorouracil / Q000494:pharmacology; D005526:Food, Formulated; D005973:Glutamine / Q000008:administration & dosage* / Q000494:pharmacology*; D007413:Intestinal Mucosa / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D007422:Intestines / Q000032:analysis; D008727:Methotrexate / Q000494:pharmacology; D009748:Nutrition Disorders / Q000378:metabolism / Q000473:pathology; D011506:Proteins / Q000032:analysis / Q000378:metabolism; D051381:Rats
D011506:Proteins; D005973:Glutamine; D004247:DNA; D005472:Fluorouracil; D008727:Methotrexate