Hb O Padova in a Spanish Family.
Haematological and biochemical aspects of a new family with heterozygous Hb O Padova [alpha 30(B11) Glu----Lys] is described. This variant has been found on a screening programme of abnormal haemoglobin in cord blood. It was separated by cellulose acetate, isoelectric focusing, citrate agar, DEAE-cellulose chromatography and by cation exchange high-performance liquid chromatography. The heat stability and the functional properties were found to be normal. This is the third family with Hb O Padova reported, all from the Mediterranean region.
Martín
G
G
Residencia Campo Arañuelo, Navalmoral de la Mata (Cáceres), España.
Villegas
A
A
Calero
F
F
del Palacio
S
S
López
J C
JC
López
M
M
Espinós
D
D
D000596:Amino Acids / Q000097:blood; D005260:Female; D006580:Genetic Carrier Screening / Q000379:methods; D006455:Hemoglobins, Abnormal / Q000032:analysis* / Q000235:genetics; D006801:Humans; D008297:Male; D010375:Pedigree; D010455:Peptides / Q000097:blood; D013030:Spain
D000596:Amino Acids; D006455:Hemoglobins, Abnormal; D010455:Peptides; C038278:hemoglobin O Padova