Juvenile chronic granulocytic leukemia, juvenile xanthogranulomas, and neurofibromatosis. Case report and review of the literature.
A 22-month-old boy had xanthomatous skin lesions, neurofibromatosis, and chronic granulocytic leukemia. Histologic examination of the xanthomatous skin lesions disclosed juvenile xanthogranulomas. Twenty-three previously published cases of this association are reviewed.
Morier
P
P
Department of Dermatovenereology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Mérot
Y
Y
Paccaud
D
D
Beck
D
D
Frenk
E
E
D006801:Humans; D007223:Infant; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000008:administration & dosage / Q000627:therapeutic use; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications* / Q000628:therapy; D008297:Male; D009456:Neurofibromatosis 1 / Q000150:complications* / Q000473:pathology; D011994:Recombinant Proteins; D012871:Skin Diseases / Q000150:complications / Q000473:pathology; D014972:Xanthogranuloma, Juvenile / Q000150:complications* / Q000473:pathology
D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins