title: [A clinical study of asymptomatic bacteriospermia].
abstract: Asymptomatic bacteriospermia was studied as an entity and its treatment was investigated in 65 subjects who clinically needed their semen tested. The obtained results are summarized as follows. 1. The rate of detection of bacteria in semen was 89.2%, and the rates of detection of aerobic and anaerobic bacteria were 55.4% and 70.8%, respectively. Forty Gram-positive strains were identified among the aerobic bacteria; rates of detection for Staphylococcus epidermidis and Enterococcus faecalis were high, and 6 strains (9.2%) of Streptococcus agalactiae were also present. The rate of detection of Gram-negative bacteria was low; only 3 strains were identified. Among the anaerobic bacteria 90 Gram-positive strains were identified; the rate of detection of Peptostreptococcus (58 strains) was high, and only 11 strains of Gram-negative bacteria were present. 2. Among cefaclor (CCL), cephalexin, lomefloxacin, latamoxef and flomoxef (FMOX), FMOX was, in general, superior to the other drugs in terms of antibacterial activities against those strains isolated from semen. 3. Bacterial changes were observed in the semen specimens from 11 subjects who were subjected to oral administration of CCL (1,500 mg/days). After the treatment, 25 strains of bacteria disappeared but 7 strains remained among 32 strains that were present before treatment, and 23 strains appeared due to superinfection.
authors.affiliation: Department of Obstetrics and Gynecology, School of Medicine, Yamagata University.
authors.forename: T
authors.initials: T
authors.lastname: Chimura
authors.forename: H
authors.initials: H
authors.lastname: Saito
mesh_terms: D042462:4-Quinolones; D000890:Anti-Infective Agents / Q000494:pharmacology; D002506:Cephalexin / Q000494:pharmacology*; D002511:Cephalosporins / Q000494:pharmacology; D013293:Enterococcus faecalis / Q000187:drug effects* / Q000302:isolation & purification; D024841:Fluoroquinolones; D006090:Gram-Negative Bacteria / Q000187:drug effects / Q000302:isolation & purification; D006094:Gram-Positive Bacteria / Q000187:drug effects / Q000302:isolation & purification; D006801:Humans; D008297:Male; D009070:Moxalactam / Q000494:pharmacology; D015363:Quinolones; D012661:Semen / Q000382:microbiology*; D013212:Staphylococcus epidermidis / Q000187:drug effects* / Q000302:isolation & purification; D013292:Streptococcus agalactiae / Q000187:drug effects / Q000302:isolation & purification
chemical_list: D042462:4-Quinolones; D000890:Anti-Infective Agents; D002511:Cephalosporins; D024841:Fluoroquinolones; D015363:Quinolones; C053091:lomefloxacin; D002506:Cephalexin; C045693:flomoxef; D009070:Moxalactam