title: Tissue plasminogen activator: the biochemistry and pharmacology of variants produced by mutagenesis.
authors.affiliation: Department of Cardiovascular Research, Genetech, Inc., South San Francisco, California 94080.
authors.forename: D L
authors.initials: DL
authors.lastname: Higgins
authors.forename: W F
authors.initials: WF
authors.lastname: Bennett
mesh_terms: D000818:Animals; D006801:Humans; D009154:Mutation; D015202:Protein Engineering; D011994:Recombinant Proteins / Q000235:genetics / Q000378:metabolism / Q000494:pharmacology; D010959:Tissue Plasminogen Activator / Q000235:genetics / Q000378:metabolism* / Q000494:pharmacology
chemical_list: D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator