title: [Use of the CO2 laser in the treatment of pathologic changes in the vulva, vagina and uterine cervix].
abstract: In the period from April 1987 to April 1990, 230 patients with pathological changes of the vulva, vagina and cervix uteri were treated with the CO2-laser. The diagnosis and pretreatment stages of the diseases were confirmed by the cytodiagnostic, colposcopic and histopathological results of the biophysics. In most cases, DNA-hybridization of human papilloma viruses confirmed their virus etiology. Twenty patients had peak condyloma of the vulva and vagina, 34 had benign cervical diseases, 65 were at the premalignant and 111 in the first stages of malignant cervical disease. Vaporizations, conical or cylindrical excisions were performed depending on the nature of disease and its localisation. The average age of operated patients was 30.6 years and the average parity 0.69. Operations were performed using analgesia and in rare cases total anesthesia. After the excision treatment, the tissue was checked histo-pathologically according to the principle of series. The complications were very rare. After operation, postoperative control was performed after 3.9 and 15 months, and later once a year. The results have shown that one treatment was sufficient in 80% of patients for curing vulvar and vaginal disease and 20% patients needed repeat because of the condyloma that relapsed. After the first treatment, benign and premalignant cervical diseases were cured in 100% of cases. In 95.4% operated patients at the first stages of cervical malignant diseases, the excisional treatment was final and in 4.6% needed an additional radical therapy because of a higher stage of lesion found by the conular histo-pathological analysis. There were no relapses relating to the cervix.
authors.affiliation: Ginekolosko-akuserska klinika, Noradni front u Beogradu.
authors.forename: B
authors.initials: B
authors.lastname: Stanimirović
authors.forename: Z
authors.initials: Z
authors.lastname: Zivanović
authors.forename: J
authors.initials: J
authors.lastname: Popović-Lazić
mesh_terms: D000328:Adult; D005260:Female; D005833:Genital Neoplasms, Female / Q000601:surgery*; D006801:Humans; D053685:Laser Therapy; D014594:Uterine Neoplasms / Q000601:surgery; D014625:Vaginal Neoplasms / Q000601:surgery; D014846:Vulvar Neoplasms / Q000601:surgery
vernacular_title: Primena CO2-lasera u lecenju patoloskih promena vulve, vagine i grlića materice.