title: [Prognostic value of hyperkinetic syndrome in children with epilepsy].
abstract: In a retrospective study the data of 43 children suffering from epilepsy were analysed. The first epileptic seizure was observed in all patients before the age of 6 years. The relationship between behavioral disturbances with hyperactivity, developmental respectively intellectual test scores, and efficiency of antileptic drug therapy have been investigated. Psychological testings were performed two times, at first after the start of drug therapy, and a second time after a period of 1 year 11 months in average. There were behavioral disturbances with hyperactivity in 20 patients. The epileptic seizures were intractable in 26 patients. The developmental respectively intellectual test scores have decreased to values below 85 in 7 patients with and 3 patients without hyperactivity. There was a decline by more than 10 points of the IQ score between first and second psychological testings in 16 patients with and 4 patients without hyperactivity, respectively in 17 patients with intractable seizures, but in one child only with prompt cessation of epileptic seizures. An increasing retardation of mental development was seen in children with hyperactivity at the start of seizures, in children with intractable seizures, but especially in patients with a combination of intractable seizures and hyperactivity.
authors.affiliation: Universitäts-Kinderklinik und Poliklinik, Jussuf Ibrahim.
authors.forename: C
authors.initials: C
authors.lastname: Bravidor
authors.forename: K
authors.initials: K
authors.lastname: Wetzel
authors.forename: K
authors.initials: K
authors.lastname: John
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use; D001289:Attention Deficit Disorder with Hyperactivity / Q000523:psychology*; D002648:Child; D002675:Child, Preschool; D004828:Epilepsies, Partial / Q000523:psychology; D004827:Epilepsy / Q000188:drug therapy / Q000523:psychology*; D005260:Female; D006801:Humans; D007223:Infant; D007361:Intelligence Tests; D008297:Male; D019965:Neurocognitive Disorders / Q000523:psychology*; D011379:Prognosis; D013036:Spasms, Infantile / Q000523:psychology*
chemical_list: D000927:Anticonvulsants
vernacular_title: Zur prognostischen Wertigkeit eines Hyperkinese-Syndroms bei epilepsiekranken Kindern.