title: Insulin stimulates postnatal development of renal tubular transport of p-aminohippurate.
abstract: The influence of repeated administration of insulin on renal tubular transport of PAH was investigated. There was a stimulating effect in young rats with an immature kidney function. The distinctly higher degree of accumulation in renal cortical slices is in accordance with the enhanced PAH excretion in 10- and 20-day-old animals.
authors.affiliation: Institute of Pharmacology and Toxicology, Friedrich Schiller University, Jena.
authors.forename: K
authors.initials: K
authors.lastname: Penzold
authors.forename: H
authors.initials: H
authors.lastname: Bräunlich
mesh_terms: D000818:Animals; D001692:Biological Transport; D005260:Female; D007328:Insulin / Q000494:pharmacology*; D007684:Kidney Tubules / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D008657:Metabolic Clearance Rate; D051381:Rats; D011919:Rats, Inbred Strains; D010130:p-Aminohippuric Acid / Q000378:metabolism*
chemical_list: D007328:Insulin; D010130:p-Aminohippuric Acid