Influence of vasotocin and isoproterenol on the in vitro motility of the follicular stalks and infundibulum in the domestic hen.
Since in the hen ovulation and oviposition are in close temporal relationship we studied the effect of vasotocin, the principal neurohypophysial oxytocic substance in birds, on in vitro motility of follicular stalks of the most recently ruptured and largest preovulatory follicle and of longitudinal and circular infundibular strips, both in the absence and the presence of a beta-adrenergic drug (isoproterenol, 1 x 10(-7) mol/l). Infundibular strips were rather insensitive to vasotocin (3 x 10(-9) - 3 x 10(-6) mol/l) either in the absence or presence of isoproterenol. However, tissue strips from the follicular stalks were significantly stimulated by vasotocin (3 x 10(-9) - 3 x 10(-7) mol/l). Isoproterenol attenuated these effects. From these in vitro studies it was concluded that vasotocin may have a facilitating function in the process of ovulation.
Wechsung
E
E
Laboratory of Veterinary Physiology, State University Centre of Antwerp, Belgium.
Houvenaghel
A
A
D000818:Animals; D002645:Chickens / Q000502:physiology*; D046508:Culture Techniques; D004347:Drug Interactions; D005260:Female; D007545:Isoproterenol / Q000494:pharmacology*; D006080:Ovarian Follicle / Q000187:drug effects*; D010057:Oviducts / Q000187:drug effects*; D014668:Vasotocin / Q000494:pharmacology*
D007545:Isoproterenol; D014668:Vasotocin