[The products of blood coagulation and fibrinolysis and their effect on pulmonary gas-exchange function].
The authors' and reported data have demonstrated the effect of hemocoagulation and fibrinolysis products on gas exchange pulmonary function in patients who suffered surgical intervention. The results of examining 20 patients with gastric carcinoma are provided. It has been established that even before operation the patients manifested the chronic pattern of the disseminated intravascular coagulation (DIC) syndrome, whose intensity increased in the postoperative period. The rise in the blood of soluble complexes of fibrin monomer (SCFM) and fibrin degradation products (FDP) formed during intravascular coagulation was established to play an important role in the impairment of gas exchange pulmonary function in the postoperative period in patients with the chronic pattern of the DIC syndrome. A possible mechanism by which SCFM and FDP influence pulmonary gas exchange is reviewed.
Riabov
G A
GA
Pasechnik
I N
IN
Emtsov
Iu G
IuG
Azizov
Iu M
IuM
D000368:Aged; D000369:Aged, 80 and over; D001777:Blood Coagulation / Q000502:physiology*; D002245:Carbon Dioxide / Q000097:blood; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D005342:Fibrinolysis / Q000502:physiology*; D006801:Humans; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D011184:Postoperative Period; D011659:Pulmonary Gas Exchange / Q000502:physiology*; D013274:Stomach Neoplasms / Q000097:blood / Q000503:physiopathology / Q000601:surgery
D005338:Fibrin Fibrinogen Degradation Products; D002245:Carbon Dioxide; D010100:Oxygen
Produkty gemokoaguliatsii i fibrinoliza i ikh vliianie na gazoobmennuiu funktsiiu legkikh.