[Taurine-activated currents in isolated neurons of the rat cerebellum].
Taurine-activated currents in isolated neurons of the rat cerebellum were studied by voltage and "concentration" clamp methods. They were transmitted by potassium and chloride ions. The dose-response curve with the dissociation constant 2 x 10(-3) mol/l was obtained. The cross-desensitization between taurine and GABA, but not between taurine and glycine was shown. These currents were also blocked by bicucullin and strychnine, but in a different manner.
Valeev
A E
AE
Garashchuk
O A
OA
Dashkin
A N
AN
D000818:Animals; D001640:Bicuculline / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D066298:In Vitro Techniques; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D010076:Oxazepam / Q000494:pharmacology; D010424:Pentobarbital / Q000494:pharmacology; D011689:Purkinje Cells / Q000187:drug effects* / Q000502:physiology*; D051381:Rats; D013331:Strychnine / Q000494:pharmacology; D013654:Taurine / Q000494:pharmacology*
D013654:Taurine; D010076:Oxazepam; D013331:Strychnine; D010424:Pentobarbital; D001640:Bicuculline
Toki, aktiviruemye taurinom, v izolirovannykh neĭronakh mozzhechka krys.