Growth hormone response to growth hormone-releasing hormone in schizophrenic patients.
Ten schizophrenic patients and five normal control subjects were challenged with growth hormone-releasing hormone in a pilot study investigating growth hormone secretion from the pituitary. The results suggest suprapituitary dysfunction in schizophrenia, but replication in a larger study is needed.
Mayerhoff
D I
DI
Department of Research, Hillside Hospital, Glen Oaks, NY 11004.
Lieberman
J A
JA
Lemus
C Z
CZ
Pollack
S
S
Schneider
B S
BS
D000328:Adult; D005260:Female; D013006:Growth Hormone / Q000097:blood* / Q000378:metabolism; D013007:Growth Hormone-Releasing Hormone / Q000008:administration & dosage / Q000494:pharmacology*; D006801:Humans; D007031:Hypothalamus / Q000503:physiopathology; D007275:Injections, Intravenous; D008297:Male; D010865:Pilot Projects; D010903:Pituitary Gland, Anterior / Q000187:drug effects* / Q000378:metabolism; D012559:Schizophrenia / Q000097:blood* / Q000503:physiopathology
D013006:Growth Hormone; D013007:Growth Hormone-Releasing Hormone