Typing of Pseudomonas aeruginosa ear infections related to outcome of treatment.
Of 142 patients with Pseudomonas aeruginosa (PSA) ear infections, 88 (62 per cent) had chronic otitis media and 54 (38 per cent) external otitis. Following serotyping and pyocin typing of their bacteria, and relating the type to outcome, patients could be divided into three groups: (1) 120 patients who had no recurrence with isolation of only one PSA strain, (2) 13 patients who had recurrent infections and in whom the same PSA strain was isolated in repeated cultures, and (3) nine patients who had recurrent disease, but who had a change in their PSA strains. Most of the PSA strains isolated from patients in groups (1) and (2) were stable to pyocin, and resistent to gentamicin. Patients in the first group were all cured initially by medical management. Of the nine patients in group (3) who had a different serotype on repeated cultures, medical treatment was successful in eight (89 per cent), but of the 13 patients in group (2) who had the same Pseudomonas aeruginosa serotype cultured, medical therapy failed in six (46 per cent) and mastoid surgery was required. Serotyping of Pseudomonas aeruginosa otitis may be helpful in predicting the type of management in patients who have recurrent infections.
Englender
M
M
Department of Otolaryngology, Children's Hospital of Pittsburgh, Pennsylvania.
Harell
M
M
Guttman
R
R
Segal
S
S
D000293:Adolescent; D000328:Adult; D000368:Aged; D015373:Bacterial Typing Techniques; D002648:Child; D002675:Child, Preschool; D006801:Humans; D008416:Mastoid / Q000601:surgery; D008875:Middle Aged; D010031:Otitis / Q000209:etiology / Q000382:microbiology* / Q000628:therapy; D010032:Otitis Externa / Q000382:microbiology; D010033:Otitis Media / Q000382:microbiology; D011552:Pseudomonas Infections / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000145:classification*; D012008:Recurrence; D012703:Serotyping; D013997:Time Factors