title: Rhinophyma-like cryptococcal infection as an early manifestation of AIDS in a hemophilia B patient.
abstract: A hemophilia B patient, seropositive for HIV antibodies since 1984, came to us in March 1989 with a severe necrotizing lesion of the nose. It was an erythematous lesion and looked like rhinophyma. Microbiological examination of the skin biopsy showed the presence of Cryptococcus neoformans. At the time of the study, the patient was in partial remission after 2 weeks of therapy with fluconazole per os 400 mg/day. He will be treated with the same therapy at maintenance dose (200 mg/day) for a long period.
authors.affiliation: 2nd Chair of Medicine, University of Padual Medical School, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Mares
authors.forename: M T
authors.initials: MT
authors.lastname: Sartori
authors.forename: M
authors.initials: M
authors.lastname: Carretta
authors.forename: A
authors.initials: A
authors.lastname: Bertaggia
authors.forename: A
authors.initials: A
authors.lastname: Girolami
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D003453:Cryptococcosis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D003937:Diagnosis, Differential; D015725:Fluconazole / Q000627:therapeutic use; D002836:Hemophilia B / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012224:Rhinophyma / Q000175:diagnosis*
chemical_list: D015725:Fluconazole