title: A case of congenital factor V deficiency combined with multiple congenital anomalies: successful management of palatoplasty.
abstract: A patient with congenital factor V deficiency combined with mental retardation and several congenital anomalies including cleft palate, dwarfism, microcephaly and right hydrocele testis is described. The levels of factor V activity and factor V antigen of plasma were significantly decreased. The platelet lysate obtained from him also showed a significantly low level of factor V activity. Palatoplasty and tooth extraction were successfully performed under transfusion therapy with fresh-frozen plasma.
authors.affiliation: Clinical Laboratory, Kyushu University Hospital, Fukuoka, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Tsuda
authors.forename: Y
authors.initials: Y
authors.lastname: Mizuno
authors.forename: T
authors.initials: T
authors.lastname: Hara
authors.forename: T
authors.initials: T
authors.lastname: Ohtsuki
authors.forename: K
authors.initials: K
authors.lastname: Ueda
authors.forename: K
authors.initials: K
authors.lastname: Matsuzaki
authors.forename: T
authors.initials: T
authors.lastname: Watanabe
mesh_terms: D000015:Abnormalities, Multiple / Q000097:blood / Q000601:surgery*; D001780:Blood Coagulation Tests; D001803:Blood Transfusion; D002648:Child; D002972:Cleft Palate / Q000097:blood / Q000601:surgery*; D005165:Factor V / Q000032:analysis; D005166:Factor V Deficiency / Q000097:blood / Q000601:surgery*; D005884:Gingival Hemorrhage / Q000097:blood / Q000601:surgery; D006801:Humans; D007430:Intraoperative Care; D008297:Male; D010159:Palate / Q000601:surgery*; D010949:Plasma; D011182:Postoperative Care; D014081:Tooth Extraction
chemical_list: D005165:Factor V