title: [Generalized status epilepticus after ingestion of ibuprofen (Brufen), disclosing systemic lupus erythematosus].
abstract: We report a case of aseptic meningoencephalitis induced by ibuprofen (Brufen) in a 24-year old unmarried woman with unrecognized systemic lupus erythematosus. The neurological manifestations induced by ibuprofen revealed the systemic disease. Clinicians confronted with aseptic meningitis or meningoencephalitis developed after treatment with a non-steroidal anti-inflammatory drug, notably ibuprofen, should investigate for systemic disease.
authors.affiliation: Service de Réanimation Médicale, CHU Angers, Angers.
authors.forename: A
authors.initials: A
authors.lastname: Lortholary
authors.forename: N
authors.initials: N
authors.lastname: Varache
authors.forename: G
authors.initials: G
authors.lastname: Bouachour
authors.forename: N
authors.initials: N
authors.lastname: Szapiro
authors.forename: P
authors.initials: P
authors.lastname: Bourrier
authors.forename: P
authors.initials: P
authors.lastname: Alquier
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007052:Ibuprofen / Q000009:adverse effects*; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008590:Meningoencephalitis / Q000139:chemically induced; D013226:Status Epilepticus / Q000139:chemically induced*
chemical_list: D007052:Ibuprofen
vernacular_title: Etat de mal comitial généralisé après prise d'ibuprofène (Brufen), révélateur d'un lupus érythémateux disséminé.