Mycosubtilins B and C: minor antibiotics from mycosubtilin-producer Bacillus subtilis.
Mycosubtilins B and C were isolated from the culture medium of Bacillus subtilis. The acid hydrolysates of these new antifungal antibiotics, like mycosubtilin, contain alpha-amino acids (Asp3, Glu1, Pro1, Ser1 and Tyr1) and a mixture of iso-C16, n-C16, iso-C17 and anteiso-C17 beta-amino acids. Mycosubtilins B and C differ by the presence of a carboxyl group and of a carboxymethyl group, respectively, instead of a carboxamide group in previously described mycosubtilin.
Besson
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F
Laboratoire de Biochemie Microbienne (CNRS URA 1176), Université Claude Bernard, Lyon, France.
Michel
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G
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000935:Antifungal Agents / Q000032:analysis / Q000096:biosynthesis* / Q000302:isolation & purification / Q000494:pharmacology; D001412:Bacillus subtilis / Q000378:metabolism*; D002845:Chromatography; D003470:Culture Media; D006868:Hydrolysis; D008074:Lipoproteins / Q000032:analysis / Q000096:biosynthesis / Q000302:isolation & purification / Q000494:pharmacology; D008969:Molecular Sequence Data; D008970:Molecular Weight; D012441:Saccharomyces cerevisiae / Q000187:drug effects; D013057:Spectrum Analysis
D000596:Amino Acids; D000935:Antifungal Agents; D003470:Culture Media; D008074:Lipoproteins; C012448:mycosubtiline