title: [Nosocomial bacteremia caused by Serratia marcescens: analysis of 44 cases].
abstract: We have evaluated 44 cases of Serratia marcescens bacteremia (SB). Most took place in surgical services (57%) and the ICU (34%). In one occasion, the cases developed as an epidemic outbreak. SB basically developed in patients with underlying diseases (neoplasia in 32%, heart disease in 16%, chronic bronchitis in 14% and miscellaneous in 20%) in whom some invasive procedure had been carried out (98%). The most common complication was septic shock. In 17 cases the infection was polymicrobial. The most common serogroup was 0:5 (41%). 98% of strains were resistant to cephalothin, 78% to ampicillin and 29% to tobramycin. The mortality rate was 39% and the most common cause of death was septic shock. The factors which adversely influenced prognosis were as follows, in order of decreasing importance: leukocytosis, thrombopenia, associated gram-positive infection, age older than 65 years, "non-typable" serogroup, unknown portal of entry, epidemic case and septic shock.
authors.affiliation: Servicio de Medicina Interna, Hospital La Paz, Universidad Autónoma de Madrid.
authors.forename: A
authors.initials: A
authors.lastname: Domínguez
authors.forename: J R
authors.initials: JR
authors.lastname: Arribas
authors.forename: M D
authors.initials: MD
authors.lastname: Folgueira
authors.forename: P
authors.initials: P
authors.lastname: Peña
authors.forename: S
authors.initials: S
authors.lastname: Luengo
authors.forename: J M
authors.initials: JM
authors.lastname: Peña
authors.forename: J J
authors.initials: JJ
authors.lastname: Vázquez
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality; D004196:Disease Outbreaks; D004352:Drug Resistance, Microbial; D004756:Enterobacteriaceae Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000401:mortality; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D018805:Sepsis / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology / Q000401:mortality; D012706:Serratia marcescens / Q000187:drug effects / Q000302:isolation & purification; D012772:Shock, Septic / Q000209:etiology / Q000401:mortality
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Bacteriemia nosocomial por Serratia marcescens: análisis de 44 casos.