A multicenter randomized controlled clinical trial of bovine surfactant for prevention of respiratory distress syndrome.
Treatment with bovine surfactant (SF-RI 1) was shown to be efficacious in improving pulmonary function and in increasing survival rate without BPD in very premature infants. Surfactant therapy did not affect the risk of major complications of prematurity.
Gortner
L
L
University Children's Hospital, Ulm, Federal Republic of Germany.
Bernsau
U
U
Hellwege
H H
HH
Hieronimi
G
G
Jorch
G
G
Reiter
H L
HL
D001724:Birth Weight; D005260:Female; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D015337:Multicenter Studies as Topic; D011663:Pulmonary Surfactants / Q000008:administration & dosage*; D016032:Randomized Controlled Trials as Topic; D012127:Respiratory Distress Syndrome, Newborn / Q000517:prevention & control*
D011663:Pulmonary Surfactants