title: Selenium supplementation improves mood in a double-blind crossover trial.
abstract: The possibility that a sub-clinical deficiency of the trace element selenium might exist in a sample of the British population was examined by giving a selenium supplemented for 5 weeks. Using a double-blind crossover design 50 subjects received either a placebo or 100 micrograms selenium on a daily basis. On three occasions they filled in the Profile of Moods state. Mood did not change when taking the placebo, whereas when taking the selenium the subjects reported a substantial improvement after both 2.5 and 5 weeks.
authors.affiliation: Department of Psychology, University College, Swansea, Wales, UK.
authors.forename: D
authors.initials: D
authors.lastname: Benton
authors.forename: R
authors.initials: R
authors.lastname: Cook
mesh_terms: D000293:Adolescent; D000328:Adult; D000339:Affect / Q000187:drug effects*; D000368:Aged; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012643:Selenium / Q000494:pharmacology*
chemical_list: D012643:Selenium