title: The effect of volume of epidural morphine on postoperative analgesia in patients undergoing cesarean section.
abstract: Ninety paturients undergoing elective cesarean section were included in this randomized study to compare the influence of the injected volume of epidural morphine (EM) on postoperative analgesia. Three similar groups of patients (n = 30 each) received 2 mg EM in 2 ml, 10 ml, and 20 ml saline respectively one hour after the last dose of 2% lidocaine. Pain scores (0-10) at rest (including uterine contraction pain) at the 2nd, 4th, 8th, 12th, 18th, and 24th h were compared among the three groups. There were no statistically significant differences of pain score among the three groups although lower pain score was present in the 20 ml group since the 8th h and thereafter. Regarding the number of patients who requested additional meperidine for pain relief 3 in 2 ml group, 2 in 10 ml group and 1 in 20 ml group respectively. The result may suggest that the influence of the injected volume of EM on postcesarean analgesia is not obvious.
authors.affiliation: Department of Anesthesia, Cathay General Hospital, Taiwan, R.O.C.
authors.forename: S L
authors.initials: SL
authors.lastname: Sun
authors.forename: K W
authors.initials: KW
authors.lastname: Cheng
authors.forename: C C
authors.initials: CC
authors.lastname: Chien
authors.forename: C J
authors.initials: CJ
authors.lastname: Che
authors.forename: C F
authors.initials: CF
authors.lastname: Chang
mesh_terms: D000328:Adult; D016362:Analgesia, Obstetrical / Q000379:methods*; D002585:Cesarean Section; D005260:Female; D006801:Humans; D007268:Injections, Epidural; D009020:Morphine / Q000008:administration & dosage* / Q000009:adverse effects; D010149:Postoperative Pain / Q000188:drug therapy*; D011247:Pregnancy
chemical_list: D009020:Morphine