[Is chirality a key to stereoselective drug action?].
The aim of this paper is to analyse examples of stereoselective binding of drugs to receptor sites. Selected examples are also given for the binding of drugs to serum albumin and for stereochemical aspects of drug metabolism.
Cegła
M
M
Zakład Chemii Organicznej, Instytut Farmakologii PAN w Krakowie.
Duszyńska
B
B
D000818:Animals; D006801:Humans; D008968:Molecular Conformation; D004364:Pharmaceutical Preparations / Q000737:chemistry / Q000378:metabolism*; D011955:Receptors, Drug / Q000378:metabolism*; D012709:Serum Albumin / Q000378:metabolism; D013237:Stereoisomerism
D004364:Pharmaceutical Preparations; D011955:Receptors, Drug; D012709:Serum Albumin
Czy chiralność jest kluczem do stereoselektywnego działania leków?