title: Syphilitic placentitis: demonstration of Treponema pallidum by immunoperoxidase staining.
abstract: We report a case of early congenital syphilis in which the placenta showed diffuse proliferative villitis and Treponema pallidum was identified by indirect immunoperoxidase stain in formalin-fixed paraffin-embedded placental tissue. This is the first report demonstrating T. pallidum in placental tissue using an immunohistochemical method.
authors.affiliation: Department of Neonatology, Kanagawa Children's Medical Center, Yokohama-city, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Ohyama
authors.forename: Y
authors.initials: Y
authors.lastname: Itani
authors.forename: Y
authors.initials: Y
authors.lastname: Tanaka
authors.forename: A
authors.initials: A
authors.lastname: Goto
authors.forename: Y
authors.initials: Y
authors.lastname: Sasaki
mesh_terms: D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007231:Infant, Newborn; D010920:Placenta / Q000382:microbiology; D010922:Placenta Diseases / Q000209:etiology / Q000382:microbiology / Q000473:pathology*; D011247:Pregnancy; D013590:Syphilis, Congenital / Q000382:microbiology / Q000473:pathology*; D014210:Treponema pallidum / Q000302:isolation & purification*