title: A guanyloribonuclease of mouse liver cytosol.
abstract: The acid RNase activity of mouse liver cytosol has been resolved into two different enzymes named acid RNase I and acid RNase II respectively. Acid RNase I is a typical pancreatic-type enzyme hydrolyzing CpN and UpN bonds. Acid RNase II, however, hydrolyzes GpN bonds in non-hydrogen-bonded regions of the substrate.
authors.affiliation: Laboratory of Biochemistry, Faculty of Chemistry, University of Thessaloniki, Greece.
authors.forename: A
authors.initials: A
authors.lastname: Pantazaki
authors.forename: J G
authors.initials: JG
authors.lastname: Georgatsos
mesh_terms: D000818:Animals; D001483:Base Sequence; D002850:Chromatography, Gel; D003600:Cytosol / Q000201:enzymology*; D004722:Endoribonucleases / Q000378:metabolism*; D005095:Exoribonucleases / Q000302:isolation & purification / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D008099:Liver / Q000201:enzymology* / Q000648:ultrastructure; D051379:Mice; D008969:Molecular Sequence Data; D006163:Ribonuclease T1 / Q000302:isolation & purification / Q000378:metabolism*; D012260:Ribonucleases / Q000378:metabolism; D013379:Substrate Specificity
chemical_list: D004722:Endoribonucleases; D005095:Exoribonucleases; D012260:Ribonucleases; C022535:exoribonuclease II; D006163:Ribonuclease T1