Microdose intravaginal levonorgestrel contraception: a multicentre clinical trial. III. The relationship between pregnancy rate and body weight. World Health Organization. Task Force on Long-Acting Systemic Agents for Fertility Regulation.
This paper investigates the relationship between pregnancy rates and body weight of 1005 women using a vaginal ring releasing 20 micrograms levonorgestrel per 24 hours. While the overall pregnancy rate at one year was 3.7%, it was found that women have an increasing risk of pregnancy with increasing body weight. For example, a woman of 40 kg has an estimated pregnancy rate of 1.7% in contrast to 9.8% for a woman of 80 kg weight.
Koetsawang
S
S
Department of Obstetrics and Gynaecology, Siriraj Hospital, Bangkok, Thailand.
Ji
G
G
Krishna
U
U
Cuadros
A
A
Dhall
G I
GI
Wyss
R
R
Rodriquez la Puenta
J
J
Andrade
A T
AT
Khan
T
T
Kononova
E S
ES
D000282:Administration, Intravaginal; D001835:Body Weight; D003274:Contraceptive Devices, Female; D005260:Female; D006801:Humans; D016912:Levonorgestrel; D015337:Multicenter Studies as Topic; D009644:Norgestrel; D011247:Pregnancy / Q000208:ethnology
D009644:Norgestrel; D016912:Levonorgestrel