Linkage of internal minisatellite loci on chromosome 1 and exclusion of autosomal dominant retinitis pigmentosa proximal to rhesus.
We report the exclusion of a locus for autosomal dominant retinitis pigmentosa proximal to the rhesus locus in a single large pedigree. In addition, a previously unreported linkage is described between two chromosome 1 markers, which confirms that a highly variable minisatellite locus is placed internally on chromosome 1.
Inglehearn
C F
CF
Department of Human Genetics, University of Newcastle upon Tyne.
Papiha
S S
SS
Jay
M
M
Wright
A F
AF
Moore
A T
AT
Bhattacharya
S S
SS
D002878:Chromosomes, Human, Pair 1; D015342:DNA Probes; D004276:DNA, Satellite / Q000235:genetics*; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D010375:Pedigree; D012174:Retinitis Pigmentosa / Q000235:genetics*; D012204:Rh-Hr Blood-Group System / Q000235:genetics
D015342:DNA Probes; D004276:DNA, Satellite; D005819:Genetic Markers; D012204:Rh-Hr Blood-Group System