[The effect of the osmotic pressure of the culture medium on cells of Francisella tularensis vaccinal strain 15].
The dependence of the growth rate of F. tularensis on the osmotic properties of the medium can be presented as a curve with the maximum in the area of 500-600 mOsm. Under these circumstances the intracellular osmotic pressure exceeds the extracellular one by 50-100 mOsm. With the rise of the osmotic pressure in the medium the increase of the concentration of K+ in the cells occurs. The energy-dependent accumulation of K+ in the cells at rest is activated by the rise of the osmotic pressure in the medium. F. tularensis are probably capable of osmoregulation, ensured by the energy-dependent osmosensitive K(+)-transporting system.
Ivanov
S A
SA
Govorunov
I G
IG
Sakharov
B V
BV
Puchkova
E O
EO
D001692:Biological Transport; D003470:Culture Media / Q000494:pharmacology*; D005604:Francisella tularensis / Q000254:growth & development* / Q000378:metabolism; D009391:Nephelometry and Turbidimetry; D009997:Osmotic Pressure; D011188:Potassium / Q000378:metabolism
D003470:Culture Media; D011188:Potassium
Vliianie osmoticheskogo davleniia kul'tural'noĭ sredy na kletki vaktsinnogo shtamma 15 Francisella tularensis.