[Oligoclonal immunoglobulins in the blood serum and monoclonal light chains in the urine in malignant diseases of myelopoiesis].
The serum of 21 patients with acute leukemia, 9 patients with chronic myeloid leukemia and 30 clinically healthy controls were examined by isoelectric focusing. The urines of 12 patients were examined by immune isofocusing. Oligoclonal bands were found in the serum of 9 patients. In the urine of 4 patients secretion of monoclonal light chains were found. In comparison with the routinely applied methods electrophoresis and immunoelectrophoresis the isoelectric focusing and the immune isofocusing gave additional information about the immunoglobulins and their light chains in 11 of 30 patients (36.7%).
Koĭcheva
N
N
Apostolov
P
P
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007147:Immunoglobulin Light Chains / Q000652:urine*; D007136:Immunoglobulins / Q000032:analysis*; D007938:Leukemia / Q000276:immunology; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009196:Myeloproliferative Disorders / Q000276:immunology*; D043025:Oligoclonal Bands
D007074:Immunoglobulin G; D007147:Immunoglobulin Light Chains; D007136:Immunoglobulins; D043025:Oligoclonal Bands
Oligoklonalni imunoglobulini v krŭvniia serum i monoklonalni leki verigi v urinata pri niakoi zlokachestveni zaboliavaniia na mielopoezata.