Lissoclinolide, the first non-nitrogenous metabolite from a Lissoclinum tunicate.
The isolation and characterization of a new metabolite from the tunicate Lissoclinum patella is described. The structure of lissoclinolide [1] was solved using spectral and chemical methods, and it is shown to be the first non-nitrogenous, non-sulfur-containing compound to be isolated from the genus Lissoclinum.
Davidson
B S
BS
Department of Medicinal Chemistry, University of Utah, Salt Lake City 84112.
Ireland
C M
CM
D015107:4-Butyrolactone / Q000031:analogs & derivatives* / Q000302:isolation & purification; D000818:Animals; D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D004926:Escherichia coli / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D014561:Urochordata / Q000032:analysis*
D000900:Anti-Bacterial Agents; C069177:lissoclinolide; D015107:4-Butyrolactone