title: Human glucose-6-phosphate dehydrogenase gene carried on a yeast artificial chromosome encodes active enzyme in monkey cells.
abstract: Yeast artificial chromosomes (YACs) permit the cloning of large tracts of human DNA. A YAC containing the human glucose-6-phosphate dehydrogenase gene is shown to encode active enzyme, supporting the inference that the YAC conserves the structure of the genomic DNA.
authors.affiliation: International Institute of Genetics and Biophysics, Naples, Italy.
authors.forename: M
authors.initials: M
authors.lastname: D'Urso
authors.forename: I
authors.initials: I
authors.lastname: Zucchi
authors.forename: A
authors.initials: A
authors.lastname: Ciccodicola
authors.forename: G
authors.initials: G
authors.lastname: Palmieri
authors.forename: F E
authors.initials: FE
authors.lastname: Abidi
authors.forename: D
authors.initials: D
authors.lastname: Schlessinger
mesh_terms: D000818:Animals; D015139:Blotting, Southern; D015825:Chromosomes, Fungal; D003001:Cloning, Molecular; D015870:Gene Expression; D015723:Gene Library; D005796:Genes; D005822:Genetic Vectors; D015894:Genome, Human; D006150:Guanine Nucleotides / Q000235:genetics*; D006153:Guanosine Diphosphate / Q000235:genetics* / Q000378:metabolism; D000882:Haplorhini; D006801:Humans; D006822:Hybrid Cells; D015183:Restriction Mapping
chemical_list: D006150:Guanine Nucleotides; D006153:Guanosine Diphosphate