title: [Proteolytic activity of lysosomes in various rat organs during total parenteral nutrition].
abstract: Specific, total and nonsedimented activities of cathepsins A, B, C and D as well as of aryl sulfatases A and B, beta-galactosidase, beta-glucuronidase and N-acetyl-beta-D-glucosaminidase were studied in liver, kidney and spleen tissues of rats under conditions of artificial intragastric and parenteral nutrition. Activity of cathepsins A and D in liver tissue as well as total activity of all the lysosomal hydrolases studied in spleen was distinctly increased in parenteral nutrition. These data suggest elevation in the functional activity of lysosomal apparatus under conditions of parenteral nutrition.
authors.forename: A V
authors.initials: AV
authors.lastname: Vasil'ev
authors.forename: N S
authors.initials: NS
authors.lastname: Bregvadze
authors.forename: L F
authors.initials: LF
authors.lastname: Poriadkov
authors.forename: V A
authors.initials: VA
authors.lastname: Tutel'ian
mesh_terms: D000818:Animals; D010450:Endopeptidases / Q000378:metabolism*; D007668:Kidney / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D008247:Lysosomes / Q000201:enzymology*; D008297:Male; D009928:Organ Specificity; D010289:Parenteral Nutrition, Total; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000201:enzymology
chemical_list: D010450:Endopeptidases
vernacular_title: Proteoliticheskaia aktivnost' lizosom v razlichnykh organakh krys v usloviiakh polnogo parenteral'nogo pitaniia.