[Comparative characteristics of bactericidal activity of various traditional and currently available antiseptics used in surgery].
Comparative study of the microbicidal activity of some traditional (hydrogen peroxide, boric acid, nitrofurazone) and currently available (Baliz-2, dioxidine, chlorhexidine bigluconate, pervomur) antiseptics against the most commonly encountered causative agents of purulent surgical infection showed 0.8%, 1.2%, and 2.4% pervomur solutions to possess the highest bactericidal and sporicidal activity. This circumstance allowed weak (0.8 and 1.2%) solutions of pervomur to be used in the clinic in 68 patients for the management of purulent postoperative complications and localized purulent infection, which improved the results of treatment significantly.
Melekhov
P A
PA
Miroshin
S I
SI
Melekhov
E P
EP
D000891:Anti-Infective Agents, Local / Q000494:pharmacology / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D001888:Boric Acids / Q000494:pharmacology / Q000627:therapeutic use; D004755:Enterobacteriaceae / Q000187:drug effects; D006801:Humans; D006861:Hydrogen Peroxide / Q000494:pharmacology / Q000627:therapeutic use; D066298:In Vitro Techniques; D009583:Nitrofurazone / Q000494:pharmacology / Q000627:therapeutic use; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D011810:Quinoxalines / Q000494:pharmacology / Q000627:therapeutic use; D013211:Staphylococcus aureus / Q000187:drug effects; D013530:Surgical Wound Infection / Q000188:drug therapy* / Q000382:microbiology
D000891:Anti-Infective Agents, Local; D001888:Boric Acids; D011810:Quinoxalines; C001077:dioxidine; D006861:Hydrogen Peroxide; C032688:boric acid; D009583:Nitrofurazone
Sravnitel'naia kharakteristika mikrobotsidnoĭ aktivnosti nekotorykh traditsionnykh i sovremennykh antiseptikov, primeniaemykh v khirurgii.