title: Clinical assessment of the Hitachi 736-30 chemistry analyzer.
abstract: We assessed the Hitachi 736-30 as a possible replacement for the SMAC I and as a laboratory cost-saving measure. For 24 analytes, both intra- and interassay precisions were acceptable; they also had good measuring ranges. Essentially no interference from lipemia was observed, while minimal interference from bilirubin was demonstrated. Hemoglobin interfered in the measurement of 12 of the analytes. Correlation with the SMAC I, Demand, Astra-8, ACA, and Varian Atomic Absorption Spectrophotometer was found to be acceptable, except for chloride which showed poor correlation with SMAC I and Astra-8 (Hitachi = 0.888 [SMAC] + 11.102, r = 0.9652; Hitachi = 0.885 [Astra] + 10.264, r = 0.9136). The Hitachi 736-30 offers reagent and method flexibility, high volume capability, and "walk-away" operation.
authors.affiliation: UCLA School of Medicine, Department of Pathology and Laboratory Medicine, 90024-1713.
authors.forename: S B
authors.initials: SB
authors.lastname: Schotters
authors.forename: J H
authors.initials: JH
authors.lastname: McBride
authors.forename: D O
authors.initials: DO
authors.lastname: Rodgerson
authors.forename: M H
authors.initials: MH
authors.lastname: McGinley
authors.forename: M
authors.initials: M
authors.lastname: Pisa
mesh_terms: D001322:Autoanalysis / Q000191:economics / Q000295:instrumentation*; D001774:Blood Chemical Analysis / Q000191:economics / Q000295:instrumentation*; D002623:Chemistry Techniques, Analytical / Q000191:economics / Q000295:instrumentation*; D003362:Cost-Benefit Analysis; D005069:Evaluation Studies as Topic; D006801:Humans; D011786:Quality Control