title: Treatment of intracranial meningiomas in patients over 70 years old.
abstract: The neurosurgeon often finds himself in the position to having to decide whether or not to operate on an elderly patient suffering from intracranial meningioma. The decision is rarely easy and the results often disappointing. We studied 46 cases of intracranial meningioma in patients over 70 years of age, 34 patients were operated on while 12 patients were not, although both groups were subjected to long term follow-up. The operative mortality rate was 12%, a rate which increased to 20% at 3 months follow-up. Various unfavourable prognostic factors were taken into consideration, the most significant of which were: poor overall clinical condition, peritumoral oedema, the presence of diabetes mellitus and the duration of surgery. A scored grading system was created to standardize surgical indications in elderly patients with cerebral meningioma. An analysis of the grading system, when applied to patients submitted to surgery, showed that the decreased patients within 3 months of surgery had a score which varied from 7 to 12, with a mean score of 10. The surviving patients had a score averaging from 10 to 16 with a mean of 13. The patients with the lowest scores (7-9) had a 100% mortality rate while those in the upper ranges (13-16) demonstrated a mortality rate of 0%. Among the conservatively treated patients the worst outcome was seen in patients with a grading equal to or less than 12.
authors.affiliation: Neurosurgical Clinic, University of Milan, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Arienta
authors.forename: M
authors.initials: M
authors.lastname: Caroli
authors.forename: F
authors.initials: F
authors.lastname: Crotti
authors.forename: R
authors.initials: R
authors.lastname: Villani
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000401:mortality / Q000601:surgery* / Q000628:therapy; D008579:Meningioma / Q000401:mortality / Q000601:surgery* / Q000628:therapy; D011183:Postoperative Complications; D016019:Survival Analysis