Mitomycin C-induced sister chromatid exchange in X chromosomes of Bovidae.
Sister chromatid exchanges (SCEs) in early- and late-replicating X chromosomes of seven female cattle (Bos taurus L.) and five female river buffalo (Bubalus bubalis L.) were studied in untreated lymphocytes and lymphocytes treated with mitomycin C (MMC). In the experiment, 577 SCEs on X chromosomes of MMC-untreated cells and 825 SCEs on X chromosomes of MMC-treated cells from both species were observed. No significant differences between the number of SCEs in early- and late-replicating X chromosomes were found even when singular species and subjects were considered.
Iannuzzi
L
L
Consiglio Nazionale delle Ricerche, Istituto di ricerche sull'Adattamento dei Bovini e dei Bufali all'Ambiente del Mezzogiorno, Naples, Italy.
Di Meo
G P
GP
Perucatti
A
A
Ferrara
L
L
D000818:Animals; D001973:Bromodeoxyuridine / Q000633:toxicity; D002020:Buffaloes; D002417:Cattle; D016009:Chi-Square Distribution; D005260:Female; D008677:Metaphase; D008934:Mitogens; D016685:Mitomycin; D008937:Mitomycins / Q000633:toxicity*; D012854:Sister Chromatid Exchange / Q000187:drug effects*; D014960:X Chromosome / Q000187:drug effects*
D008934:Mitogens; D008937:Mitomycins; D016685:Mitomycin; D001973:Bromodeoxyuridine