title: Characterization and measurement of immunoglobulins in the grey seal (Halichoerus grypus).
abstract: Immunoglobulin concentrations were measured in the serum and colostrum of adult and pup Grey seals from North Rona in the outer Hebrides and the Isle of May in the Firth of Forth. IgG was shown to be the main immunoglobulin and two subclasses were identified. Serum immunoglobulin content was low in the week-old pups and increased up to 5 weeks, although it remained substantially lower than in the adults. Colostral immunoglobulins were high and cannot explain the low values in the pup serum. It is considered that the increased opportunistic infections seen in Grey seal pups may be related to this low immunoglobulin status.
authors.affiliation: Department of Veterinary Pathology, University of Liverpool, U.K.
authors.forename: S D
authors.initials: SD
authors.lastname: Carter
authors.forename: D E
authors.initials: DE
authors.lastname: Hughes
authors.forename: J R
authors.initials: JR
authors.lastname: Baker
mesh_terms: D000818:Animals; D010872:Caniformia / Q000097:blood*; D002852:Chromatography, Ion Exchange; D003126:Colostrum / Q000378:metabolism*; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D005779:Immunodiffusion; D007074:Immunoglobulin G / Q000378:metabolism; D007136:Immunoglobulins / Q000145:classification / Q000378:metabolism*; D009994:Osmolar Concentration; D011247:Pregnancy; D046048:Seals, Earless / Q000097:blood* / Q000378:metabolism
chemical_list: D007074:Immunoglobulin G; D007136:Immunoglobulins