[Studies on immunoregulation and hypersensitivity of secretary otitis media].
Sixty patients with secretary otitis media (SOM) and 50 control cases were studied for their cellular immunity and hypersensitivity. Most of patients revealed that total T or T cell subpopulations were below those of the control. Eighty percent of patients had high serum IgE level and 81.2% as Positive in intradermal skin tests on inhalant allergy, but only 51.7% of patients had clinical symptoms of allergy. It was found immunologically that SOM occurred more frequently in allergic patients and most of them had abnormality of immunoregulation, and that there was a subclinical allergy for some of the patients. Allergy might play a significant role in the etiology of this disease. Authors suggest that it is necessary for patients with SOM to have some tests and treatment of immunology.
Liu
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Long
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R
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology*; D007111:Immunity, Cellular; D007073:Immunoglobulin E / Q000032:analysis; D008297:Male; D008875:Middle Aged; D010034:Otitis Media with Effusion / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology*
D007073:Immunoglobulin E