title: Once-daily ethosuximide in the treatment of absence epilepsy.
abstract: Once-daily ethosuximide was used to treat 10 consecutive children with typical absence seizures. Three patients had gastrointestinal side effects which resolved when the same total daily dose was divided into 2 doses. Two other patients continued to have seizures on ethosuximide, whether given once or twice daily. Five patients had complete seizure control without adverse effects on once-daily ethosuximide.
authors.affiliation: Department of Pediatrics, Dalhousie University, Halifax, Nova Scotia, Canada.
authors.forename: J M
authors.initials: JM
authors.lastname: Dooley
authors.forename: P R
authors.initials: PR
authors.lastname: Camfield
authors.forename: C S
authors.initials: CS
authors.lastname: Camfield
authors.forename: A D
authors.initials: AD
authors.lastname: Fraser
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D004832:Epilepsy, Absence / Q000188:drug therapy*; D005013:Ethosuximide / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006801:Humans; D009325:Nausea / Q000139:chemically induced
chemical_list: D005013:Ethosuximide