The role of ligand-receptor interactions in disease.
Ligand-receptor interactions play a determining role in many cell biological interactions. Mutations of ligands or receptors can both cause a disturbance in these interactions. In this paper an example will be given of these types of defects. Finally it will be speculated which role receptor mechanisms may play in the field of dermatology.
Vermeer
B J
BJ
Department of Dermatology, University Medical Center, Leiden, The Netherlands.
Leuven
J A
JA
D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000378:metabolism / Q000503:physiopathology*; D008024:Ligands; D011973:Receptors, LDL / Q000378:metabolism / Q000502:physiology*
D008024:Ligands; D011973:Receptors, LDL