Neuropeptide Y: a missing link?
Yet another 'orphan' molecule that had to find its place in life after isolation and sequencing, neuropeptide Y appears to be an important cardiovascular neuroregulator and also links the sympathetic and renin-angiotensin systems. The peptide's physiologic and pathophysiologic roles, as well as its potential therapeutic value, are examined.
Waeber
B
B
Division of Hypertension, Centre Hospitalier Universitaire, Lausanne, Switzerland.
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D003331:Coronary Vessels / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D009451:Neuroeffector Junction / Q000187:drug effects; D009478:Neuropeptide Y / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism / Q000502:physiology*; D051381:Rats; D012084:Renin-Angiotensin System / Q000187:drug effects; D012982:Sodium, Dietary / Q000008:administration & dosage; D013564:Sympathetic Nervous System / Q000187:drug effects; D014661:Vasoconstriction / Q000187:drug effects
D009478:Neuropeptide Y; D012982:Sodium, Dietary