[The effect of lysine-enriched bread on the formation of N-nitrosamines from their precursors in the stomach of dogs].
Data are presented on nitrosamine (NA) formation in the stomach of dogs after per os intake of their precursors--morpholine (or diethylamine) and sodium nitrite. It has been shown that bread enriched with lysine given to dogs in combination with the precursors promotes a five-six-fold reduction of carcinogenic NA formation in the dog's stomach as compared to the control.
Zhukova
G F
GF
Vasilevskaia
L S
LS
Iurchenko
V A
VA
Maslova
E A
EA
D000818:Animals; D001939:Bread; D004048:Diethylamines / Q000493:pharmacokinetics*; D004285:Dogs; D005503:Food Additives; D005753:Gastric Mucosa / Q000378:metabolism; D008239:Lysine / Q000494:pharmacology*; D009025:Morpholines / Q000493:pharmacokinetics*; D009602:Nitrosamines / Q000378:metabolism*; D012977:Sodium Nitrite / Q000008:administration & dosage; D013270:Stomach / Q000187:drug effects*; D013997:Time Factors
D004048:Diethylamines; D005503:Food Additives; D009025:Morpholines; D009602:Nitrosamines; C037574:morpholine; C034281:diethylamine; D008239:Lysine; D012977:Sodium Nitrite
Vliianie obogashchennogo lizinom khleba na obrazovanie N-nitrozaminov iz ikh predshestvennikov v zheludke sobak.