Absorption of intranasal salmon calcitonin in normal subjects and hypogonadic men.
The absorption kinetics of intranasal salmon calcitonin were assessed in 4 normal subjects and 9 patients with Klinefelter's syndrome. After administration, absorption occurred within 5 minutes. There was a highly significant correlation between the amount administered and the amount absorbed (r = -0.83, P less than 0.0005).
Pun
K K
KK
Department of Medicine, University of Hong Kong.
Chan
L W
LW
Lau
P
P
Ho
P W
PW
Wang
C
C
D000281:Administration, Intranasal; D000293:Adolescent; D000328:Adult; D000818:Animals; D002116:Calcitonin / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000627:therapeutic use; D006801:Humans; D007006:Hypogonadism / Q000188:drug therapy / Q000378:metabolism*; D008297:Male; D012474:Salmon
D002116:Calcitonin