[Intracerebral hemorrhage related with cerebral amyloid angiopathy].
The clinical and neuropathologic findings in 11 cases with intracerebral hemorrhages related to CAA were reported. Their age ranged from 45 to 79 years, the average being 61.8 years. The hematomas were all in cerebral lobes, except two patients whose hematomas were in the basal ganglia and thalamus. These hematomas were in irregular shapes, ruptured into ventricles and/or subarachnoid space in all cases. The vessel's wall of arteries in the leptomeninges, superficial cortex and those adjacent to hemorrhagic foci showed considerable thickness. Hemorrhagic foci showed considerable thickness. Homogeneously eosinophilic structures deposited in these vessel's wall of several small arteries. Some of these vessels showed luminal stenosis. Congo red staining confirmed characteristic amyloid apple-green birefringence under polarizing microscope.
Xu
H Q
HQ
Department of Biophysics, Shanghai Medical University.
D000368:Aged; D000682:Amyloid / Q000378:metabolism*; D001160:Arterioles / Q000737:chemistry; D001921:Brain / Q000098:blood supply / Q000378:metabolism* / Q000473:pathology; D002543:Cerebral Hemorrhage / Q000378:metabolism / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D000682:Amyloid