Nonsteroidal antiinflammatory drug hydroxamic acids. Dual inhibitors of both cyclooxygenase and 5-lipoxygenase.
Flynn
D L
DL
Department of Chemistry, Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, Ann Arbor, Michigan 48105.
Capiris
T
T
Cetenko
W J
WJ
Connor
D T
DT
Dyer
R D
RD
Kostlan
C R
CR
Nies
D E
DE
Schrier
D J
DJ
Sircar
J C
JC
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000494:pharmacology*; D001091:Arachidonate Lipoxygenases / Q000037:antagonists & inhibitors*; D016861:Cyclooxygenase Inhibitors; D006877:Hydroxamic Acids / Q000009:adverse effects / Q000494:pharmacology*; D007052:Ibuprofen / Q000031:analogs & derivatives / Q000627:therapeutic use; D007213:Indomethacin / Q000031:analogs & derivatives / Q000627:therapeutic use; D016859:Lipoxygenase Inhibitors; D008469:Meclofenamic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use
D000894:Anti-Inflammatory Agents, Non-Steroidal; D016861:Cyclooxygenase Inhibitors; D006877:Hydroxamic Acids; D016859:Lipoxygenase Inhibitors; D008469:Meclofenamic Acid; D001091:Arachidonate Lipoxygenases; D007052:Ibuprofen; D007213:Indomethacin