Large cell lymphoma masquerading as a viral retinitis.
A 37 year old woman presented with a bilateral vitritis. 4 months previously, she had developed in her left eye a necrotizing retinitis compatible with acute retinal necrosis (ARN). A trial of Acyclovir was unsuccessful as were systemic steroids. Over the following 2 months the vitritis worsened. The patient underwent a diagnostic vitrectomy revealing the presence of a large B-cell lymphoma with a predominance of lambda light chains.
de Smet
M D
MD
Laboratory of Immunology, National Eye Institute, Bethesda, Maryland.
Nussenblatt
R B
RB
Davis
J L
JL
Palestine
A G
AG
D000328:Adult; D000911:Antibodies, Monoclonal / Q000276:immunology; D003951:Diagnostic Errors; D015828:Eye Infections, Viral / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007146:Immunoglobulin lambda-Chains / Q000276:immunology; D016393:Lymphoma, B-Cell / Q000150:complications / Q000175:diagnosis*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D012163:Retinal Detachment / Q000209:etiology; D012173:Retinitis / Q000175:diagnosis* / Q000209:etiology; D014821:Vitrectomy
D000911:Antibodies, Monoclonal; D007146:Immunoglobulin lambda-Chains