[The correlation between the serum levels of osteocalcin and 24,25-dihydroxyvitamin D in Paget's disease of bone].
The influence of 24,25-dihydroxyvitamin D on different seric levels of osteocalcin in Paget's disease of the bone and in 11 of the control group, other parameters were also determined such as: seric levels of calcium, phosphate, parathormone, osteocalcin, 25-hydroxyvitamin D an 1,25 dihydroxyvitamin D. We observed that patients with Paget's disease showed increased or normal levels of seric osteocalcin, despite the high bone remodelling and significantly low level of 24,25-dihydroxyvitamin D observed in patients with high levels of osteocalcin. At the same time, we noticed a negative lineal correlation between both parameters. We suggest that 24,25-hydroxyvitamin D can be one of the important factors in producing increased or normal levels of osteocalcin in patients with Paget's disease of the bone.
Castro Errecarborde
N
N
Unidad Metabólica, Fundación Jiménez Díaz, Madrid.
de la Piedra Gordo
C
C
Rapado Errazti
A
A
D015650:24,25-Dihydroxyvitamin D 3 / Q000097:blood*; D000368:Aged; D002117:Calcitriol / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010001:Osteitis Deformans / Q000097:blood*; D015675:Osteocalcin / Q000097:blood*
D015675:Osteocalcin; D015650:24,25-Dihydroxyvitamin D 3; D002117:Calcitriol
Correlación entre los niveles séricos de osteocalcina y de 24,25 dihidroxivitamina D en la enfermedad ósea de Paget.