A new liquid material for embolization of arteriovenous malformations.
We have developed a liquid material for embolization of arteriovenous malformations that is a mixture of ethylene vinyl alcohol copolymer and metrizamide dissolved in dimethyl sulfoxide. Upon contact with blood, dimethyl sulfoxide rapidly diffuses into the blood and forms an ethylene vinyl alcohol copolymer elastic soft sponge that obstructs both the feeder and the nidus. The material, which is not adhesive, was used for embolization of three left cerebral arteriovenous malformations with satisfactory results.
Taki
W
W
Department of Neurosurgery, Kyoto University Medical School, Japan.
Yonekawa
Y
Y
Iwata
H
H
Uno
A
A
Yamashita
K
K
Amemiya
H
H
D000293:Adolescent; D000328:Adult; D001165:Arteriovenous Malformations / Q000000981:diagnostic imaging / Q000628:therapy*; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging / Q000628:therapy*; D004121:Dimethyl Sulfoxide / Q000627:therapeutic use*; D004338:Drug Combinations; D004621:Embolization, Therapeutic; D005260:Female; D006801:Humans; D008793:Metrizamide / Q000627:therapeutic use*; D008875:Middle Aged; D011145:Polyvinyls / Q000627:therapeutic use*; D011859:Radiography
D004338:Drug Combinations; D011145:Polyvinyls; C020320:ethylene-vinyl alcohol copolymer; D008793:Metrizamide; D004121:Dimethyl Sulfoxide