[Morphological studies of the effects of protein-free diet and branched-chain amino acids (aminosteril-hepa (Frasenius)) on experimental thioacetamide-induced liver damage].
The studies were performed in two groups of rats in which experimental hepatic encephalopathy was induced with tioacetamide++. One group of rats on protein-free diet was given intraperitoneally a mixture of amino-acids (Aminosteril-Hepa), the other one was given proteins in the diet in a dose 1 g per kg of body weight. Histological and histochemical studies revealed that free-protein diet with a mixture of aliphatic polybranched amino-acids (Aminosteril-Hepa) inhibited hepatotoxic thioacetamide+ action on the rat liver.
Nowak
H F
HF
Zakład Anatomii Patologicznej AM w Białymstoku.
Zimnoch
L
L
Boroń
P
P
Farbiszewski
R
R
Szpakowska
T
T
Flisiak
R
R
Pytel
B
B
D000596:Amino Acids / Q000008:administration & dosage*; D000597:Amino Acids, Branched-Chain / Q000008:administration & dosage*; D000818:Animals; D003131:Combined Modality Therapy; D004044:Dietary Proteins / Q000008:administration & dosage*; D004195:Disease Models, Animal; D006501:Hepatic Encephalopathy / Q000139:chemically induced / Q000178:diet therapy / Q000473:pathology*; D008099:Liver / Q000187:drug effects / Q000473:pathology*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013853:Thioacetamide
D000596:Amino Acids; D000597:Amino Acids, Branched-Chain; D004044:Dietary Proteins; C064930:aminosteril-hepa; D013853:Thioacetamide
Badania morfologiczne nad wpływem diety bezbiałkowej i stosowania aminokwasów wielorozgałezionych (preparat Aminosteril-Hepa firmy Frasenius) na watrobe doświadczalnie uszkodzona tioacetamidem.