title: The occurrence of leukemia in a patient with pulmonary asbestosis.
abstract: A 77-year-old man, who had been a subway construction worker, was admitted to our hospital for surgical treatment of left cheek carcinoma and an examination for pancytopenia on November 17, 1986. Bone marrow aspiration revealed that 10% of the nucleated cells were blasts with morphological atypism. Bone marrow biopsy showed hypocellular marrow and a diffuse increase of argyrophil fibers with the presence of asbestos fibers was observed by microscope. A chest X-ray showed the findings of old tuberculosis and pulmonary asbestosis, and asbestos fibers were demonstrated in the broncho-pulmonary lavage fluid. He was diagnosed to have pulmonary asbestosis complicated with hypoplastic low percentage leukemia.
authors.affiliation: First Department of Internal Medicine, Niigata University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Chinushi
authors.forename: S
authors.initials: S
authors.lastname: Koyama
authors.forename: M
authors.initials: M
authors.lastname: Takahashi
authors.forename: A
authors.initials: A
authors.lastname: Shibata
authors.forename: I
authors.initials: I
authors.lastname: Emura
mesh_terms: D000368:Aged; D001194:Asbestos / Q000009:adverse effects* / Q000032:analysis; D001195:Asbestosis / Q000150:complications*; D001853:Bone Marrow / Q000737:chemistry / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000150:complications; D003252:Construction Materials; D005153:Facial Neoplasms / Q000150:complications; D006801:Humans; D007938:Leukemia / Q000209:etiology* / Q000473:pathology; D008297:Male; D009378:Neoplasms, Multiple Primary; D016273:Occupational Exposure; D014397:Tuberculosis, Pulmonary / Q000150:complications
chemical_list: D001194:Asbestos