title: Transplantation of islets of Langerhans isolated by Trowell's T8 medium in outbred rats: effect of cyclosporine.
abstract: This study was carried out to investigate the efficacy of cyclosporine to prolong islets isolated by collagenase in Trowell's T8 medium and Ficoll gradient separation. Our results demonstrate that a short course of cyclosporine is effective in minimizing rejection of transplanted islets in outbred rats.
authors.affiliation: Department of Organ Transplantation, Faculty of Medicine, Kuwait University, Safat.
authors.forename: I H
authors.initials: IH
authors.lastname: al-Abdullah
authors.forename: M S
authors.initials: MS
authors.lastname: Kumar
authors.forename: M S
authors.initials: MS
authors.lastname: al-Adnani
authors.forename: G M
authors.initials: GM
authors.lastname: Abouna
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D002469:Cell Separation / Q000379:methods; D002499:Centrifugation, Density Gradient; D003470:Culture Media; D003524:Cyclosporins / Q000627:therapeutic use*; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000601:surgery*; D005362:Ficoll; D006084:Graft Rejection; D006085:Graft Survival; D007515:Islets of Langerhans / Q000166:cytology*; D016381:Islets of Langerhans Transplantation / Q000276:immunology* / Q000473:pathology; D008099:Liver / Q000473:pathology; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D001786:Blood Glucose; D003470:Culture Media; D003524:Cyclosporins; D005362:Ficoll