Evidence that UGA is read as a tryptophan codon rather than as a stop codon by Mycoplasma pneumoniae, Mycoplasma genitalium, and Mycoplasma gallisepticum.
Molecular cloning and sequencing showed that Mycoplasma gallisepticum, like Mycoplasma capricolum, contains both tRNA(UCA) and tRNA(CCA) genes, while Mycoplasma pneumoniae and Mycoplasma genitalium each appear to have only a tRNA(UCA) gene. Therefore, these mycoplasma species contain a tRNA with the anticodon UCA that can translate both UGA and UGG codons.
Inamine
J M
JM
Department of Pediatrics, University of North Carolina, Chapel Hill 27599-7220.
Ho
K C
KC
Loechel
S
S
Hu
P C
PC
D001483:Base Sequence; D003001:Cloning, Molecular; D003062:Codon; D008969:Molecular Sequence Data; D009174:Mycoplasma / Q000235:genetics*; D009177:Mycoplasma pneumoniae / Q000235:genetics*; D012333:RNA, Messenger; D012343:RNA, Transfer / Q000032:analysis; D014364:Tryptophan / Q000235:genetics*
D003062:Codon; D012333:RNA, Messenger; D014364:Tryptophan; D012343:RNA, Transfer