Epilepsy and brain tumors: implications for treatment.
Primary intraparenchymal tumors of the brain are important etiologic factors in partial or focal epilepsy. Indolent low-grade gliomas may be associated with a long-standing seizure disorder refractory to medical treatment. Surgical resection of the neoplasm and the epileptogenic area may render patients seizure-free. Removal of the tumor alone may also be associated with an excellent survival rate and surgical outcome. Conventional neurosurgical procedures are restricted in patients with tumors that are deep-seated lesions or involve functional cerebral cortex. Computer-assisted stereotactic surgical procedures have been developed for biopsy and resection of intra-axial brain-mass lesions. Stereotactic tumor resection may allow pathological determination of intracranial lesions and produce a worthwhile reduction in seizure activity in some patients with intractable partial epilepsy.
Cascino
G D
GD
Department of Neurology, Mayo Medical School, Rochester, MN 55905.
D000328:Adult; D001921:Brain / Q000601:surgery; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D002648:Child; D004828:Epilepsies, Partial / Q000209:etiology / Q000601:surgery; D004827:Epilepsy / Q000209:etiology / Q000601:surgery*; D005910:Glioma / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013238:Stereotaxic Techniques; D013813:Therapy, Computer-Assisted