title: Living-unrelated renal transplantation at the University of Wisconsin.
abstract: 1. Use of LUrDs under a DST protocol results in a 70% actuarial graft survival at 6 years which is not statistically different from haploidentical or primary cadaver recipients transplanted over the same time period. 2. Sensitization is common, despite the use of Aza, especially in husband-to-wife donor-to-recipient relationship. 3. Rejection occurs frequently, despite the use of DST, however, it is usually reversible. The high rejection rate did not influence the quality of long-term graft survival with very few patients losing grafts to chronic rejection. 4. Expansion of the use of LUrDs could help provide additional organs for transplantation.
authors.affiliation: Department of Medicine, University of Wisconsin School of Medical, Madison.
authors.forename: J D
authors.initials: JD
authors.lastname: Pirsch
authors.forename: A M
authors.initials: AM
authors.lastname: D'Alessandro
authors.forename: H W
authors.initials: HW
authors.lastname: Sollinger
authors.forename: B J
authors.initials: BJ
authors.lastname: Voss
authors.forename: S J
authors.initials: SJ
authors.lastname: Knechtle
authors.forename: A
authors.initials: A
authors.lastname: Reed
authors.forename: M
authors.initials: M
authors.lastname: Kalayoglu
authors.forename: F O
authors.initials: FO
authors.lastname: Belzer
mesh_terms: D000328:Adult; D002102:Cadaver; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection; D006085:Graft Survival; D006650:Histocompatibility Testing; D006801:Humans; D007165:Immunosuppression Therapy / Q000379:methods; D016030:Kidney Transplantation / Q000276:immunology; D008297:Male; D012189:Retrospective Studies; D014019:Tissue Donors; D014922:Wisconsin