title: Histiocytosis X: successful treatment with recombinant interferon-alpha A.
abstract: Two patients with disseminated histiocytosis X were treated with intramuscular injections of recombinant interferon alpha A. The bone, skin and visceral lesions of these patients diminished rapidly. Significant sclerosis and recalcification of bone were observed. From our limited but positive experience, it would be justified to consider the use of interferon in patients with disseminated histiocytosis X.
authors.affiliation: Department of Pediatrics, School of Medicine, University of Hirosaki, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Sato
authors.forename: Y
authors.initials: Y
authors.lastname: Ikeda
authors.forename: E
authors.initials: E
authors.lastname: Ito
authors.forename: T
authors.initials: T
authors.lastname: Miyano
authors.forename: K
authors.initials: K
authors.lastname: Kawauchi
authors.forename: M
authors.initials: M
authors.lastname: Yokoyama
authors.forename: Y
authors.initials: Y
authors.lastname: Kamata
mesh_terms: D006646:Histiocytosis, Langerhans-Cell / Q000628:therapy*; D006801:Humans; D007223:Infant; D007370:Interferon Type I / Q000627:therapeutic use*; D008297:Male; D011994:Recombinant Proteins
chemical_list: D007370:Interferon Type I; D011994:Recombinant Proteins