title: Isolation and characterization of HIV-2ben obtained from a patient with predominantly neurological defects.
abstract: A HIV-2 strain named HIV-2ben was isolated from peripheral blood lymphocytes of a patient who, since 1984, had developed neurological symptoms such as Raynaud's syndrome, followed by paresthesia of extremities and ataxia, and finally paraparesis of the legs and incontinence. This new isolate could be distinguished from HIV-2rod by antibody-binding epitopes, peptide maps of core p24 and p18 polypeptides and restriction endonuclease cleavage pattern.
authors.affiliation: German Primate Center, Göttingen, FRG.
authors.forename: J
authors.initials: J
authors.lastname: Schneider
authors.forename: W
authors.initials: W
authors.lastname: Lüke
authors.forename: F
authors.initials: F
authors.lastname: Kirchhoff
authors.forename: R
authors.initials: R
authors.lastname: Jung
authors.forename: E
authors.initials: E
authors.lastname: Jurkiewicz
authors.forename: C
authors.initials: C
authors.lastname: Stahl-Hennig
authors.forename: S
authors.initials: S
authors.lastname: Nick
authors.forename: E
authors.initials: E
authors.lastname: Klemm
authors.forename: K D
authors.initials: KD
authors.lastname: Jentsch
authors.forename: G
authors.initials: G
authors.lastname: Hunsmann
mesh_terms: D000818:Animals; D015683:Gene Products, gag / Q000032:analysis; D016655:HIV Core Protein p24; D015498:HIV-2 / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D009422:Nervous System Diseases / Q000382:microbiology*; D010449:Peptide Mapping; D011817:Rabbits; D014758:Viral Core Proteins / Q000032:analysis
chemical_list: D015683:Gene Products, gag; D016655:HIV Core Protein p24; D014758:Viral Core Proteins