[Preoperative aspects of blood rheology in patients who developed multiple organ failure following cardiac surgery].
The relationship between preoperative hemorheology and postoperative course was studied in 38 patients who had undergone open heart surgery for valvular diseases (mean age, 53 +/- 2 S.E. years). Twelve patients had multiple organ failures (MOF) one week after surgery, while the remaining 26 patients were in satisfactory condition. The hematocrit (Ht) was 34.8 +/- 1.6 S.E.% in patients with MOF and it was 40.4 +/- 0.9 S.E.% in patients without MOF. The difference was significant. Blood viscosities (eta) at shear rates of 94.5 sec-1 and 0.376 sec-1 also were significantly lower in patients with MOF compared with those without MOF. However, oxygen delivery (Ht/eta at a shear rate of 94.5 sec-1) in terms of hemorheology, plasma viscosity, and erythrocyte deformability were not significantly different between the two groups. These data suggest that patients with a low hematocrit and a low viscosity are likely to suffer from MOF following surgery.
Kato
T
T
Department of Anesthesiology, Toyokawa City Hospital, Aichi.
Tsushima
N
N
D000328:Adult; D000368:Aged; D001809:Blood Viscosity / Q000502:physiology*; D006348:Cardiac Surgical Procedures; D006400:Hematocrit; D006801:Humans; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000097:blood*; D011183:Postoperative Complications / Q000097:blood*