The effect of ethanol on platelet function and vascular prostanoids.
The present review will discuss the effects of ethanol on platelet function and vascular prostanoids. Whenever possible we have considered human studies because there are marked species differences in platelet function and vascular prostanoid release even in the absence of ethanol. Because of the specialised nature of some parts of the text, we have included brief introductions to help readers who are not familiar with this field.
Mikhailidis
D P
DP
Department of Chemical Pathology and Human Metabolism, Royal Free Hospital and School of Medicine, University of London, UK.
Barradas
M A
MA
Jeremy
J Y
JY
D000437:Alcoholism / Q000097:blood; D001760:Bleeding Time; D001792:Blood Platelets / Q000187:drug effects*; D011464:Epoprostenol / Q000096:biosynthesis*; D000431:Ethanol / Q000633:toxicity*; D006801:Humans; D010974:Platelet Aggregation / Q000187:drug effects; D010976:Platelet Count; D013928:Thromboxane A2 / Q000378:metabolism*
D000431:Ethanol; D013928:Thromboxane A2; D011464:Epoprostenol