title: [Proteases and their inhibitors in patients with benign ovarian tumors].
abstract: Activities of neutral and weakly alkaline proteases, cathepsins, alpha 1-inhibitor of proteases were studied with simultaneous estimation of follicle stimulating, luteinizing hormones and progesterone in healthy persons and in patients with ovary benign tumors. A decrease in content of the peptide hormones was accompanied by an increase in proteolytic activity as well as by deterioration of these proteases ratio during various phases of the cycle; these alterations appear to be involved in pathogenesis of the disease.
authors.forename: V F
authors.initials: VF
authors.lastname: Nagornaia
mesh_terms: D010450:Endopeptidases / Q000097:blood*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000378:metabolism; D006801:Humans; D007986:Luteinizing Hormone / Q000378:metabolism; D008597:Menstrual Cycle; D010051:Ovarian Neoplasms / Q000201:enzymology* / Q000503:physiopathology; D011374:Progesterone / Q000378:metabolism; D011480:Protease Inhibitors / Q000097:blood*
chemical_list: D011480:Protease Inhibitors; D011374:Progesterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D010450:Endopeptidases
vernacular_title: Proteazy i ikh ingibitory u bol'nykh s dobrokachestvennymi opukholiami iaichnikov.