Effect of unilateral vagotomy on serum gonadotropin concentration in rats with two testes and in hemicastrates.
The effect of right- or left-sided vagotomy on serum gonadotropin secretion was studied in rats with two testes and in hemicastrates. Right-sided vagotomy in animals with two testes in situ induced a very marked rise in serum LH levels. Left-sided vagotomy was also accompanied with a slight increase in LH secretion. The difference in serum LH levels between right-and left-sided vagotomized animals was significant. FSH levels were unaffected by either right- or left-sided vagotomy. Removal of the right or of the left testis resulted in a significant increase in serum gonadotropin levels. Unilateral vagotomy in hemicastrates did not alter the hemicastration-induced changes in serum gonadotropin hormone levels. These data indicate that the vagus nerve might have a modulatory role in the control of LH secretion in rats with two testes but not in hemicastrates. The different response in LH levels after right-sided and left-sided vagotomy suggests a functional asymmetry of the vagus nerve in the regulation of LH secretion.
Gerendai
I
I
2nd Department of Anatomy, Semmelweis University Medical School, Budapest, Hungary.
Motta
M
M
D000818:Animals; D001835:Body Weight / Q000502:physiology; D005640:Follicle Stimulating Hormone / Q000097:blood*; D007986:Luteinizing Hormone / Q000097:blood*; D008297:Male; D009919:Orchiectomy; D009929:Organ Size / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D013737:Testis / Q000033:anatomy & histology / Q000294:innervation / Q000378:metabolism / Q000502:physiology*; D014628:Vagotomy
D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone