title: Multiple sclerosis in adolescents: CT and MR findings.
abstract: The MR and CT findings in 12 adolescents with multiple sclerosis were compared with reported findings in adults. The adolescent group showed a more striking female predominance, more severe disease characteristics, and more frequent infratentorial involvement. Cortical atrophy and abnormal iron accumulation in the basal ganglia were uncommon in the adolescents. Neither group demonstrated a correlation between symptom severity and either extent or location of disease as delineated by MR imaging. MR was more sensitive than CT in detecting demyelinating plaques.
authors.affiliation: Department of Radiology, University of Utah Medical Center, Salt Lake City 84132.
authors.forename: A G
authors.initials: AG
authors.lastname: Osborn
authors.forename: H R
authors.initials: HR
authors.lastname: Harnsberger
authors.forename: W R
authors.initials: WR
authors.lastname: Smoker
authors.forename: R S
authors.initials: RS
authors.lastname: Boyer
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009103:Multiple Sclerosis / Q000175:diagnosis* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed