[Rhesus phenotype and lymphocyte subpopulations].
Lymphocyte subpopulations identified by OK3, OK4 and OK8 monoclonal antibodies were studied as a function of certain Rh markers in 2 groups of subjects: 47 children and adolescents with proven reaginic IgE-dependent allergies and 29 healthy adult controls. The Rh antigens C and c were evaluated in their 3 possible configurations: CC, Cc and cc. In both groups studied, the same significant distribution was observed. Allergic cc subjects had the most CD4+ lymphocytes (43.4%) versus CC (34%) and Cc (33.7%), as compared to control cc (42.05%), CC (36.1%). The possible clinical implications of these findings are discussed.
de Montis
G
G
Hôpital de jour, Service de Pédiatrie B, Paris.
Maheu
E
E
Huchet
G
G
Mace
B
B
Pompidou
A
A
D000293:Adolescent; D000328:Adult; D000911:Antibodies, Monoclonal / Q000276:immunology*; D002648:Child; D006801:Humans; D010641:Phenotype; D012016:Reference Values; D012130:Respiratory Hypersensitivity / Q000276:immunology*; D012204:Rh-Hr Blood-Group System / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
D000911:Antibodies, Monoclonal; D012204:Rh-Hr Blood-Group System
Phénotype Rhésus et sous-populations lymphocytaires.