Reinfusion of UV-irradiated blood in the treatment of infection. I. Experimental infection with staphylococci.
During the last 10 years, reinfusion of UV-irradiated blood has been rediscovered again as a therapeutic method suitable in the treatment of a variety of diseases. The described series of model experiments on rabbits confirm its beneficial effects in the treatment of staphylococcal infection: the control animals reinfused blood not exposed to UV radiation died all within 48 hours after injected with a suspension of live Staphylococcus aureus culture; all rabbits reinfused UV-irradiated blood (2 ml per kg body weight) survived the whole period of observation (30 days); reinfusion of UV-irradiated blood in a volume reduced to 1 ml.kg-1 body weight prolonged the animals' life-span to 96 or 120 hours.
Rosina
J
J
Institute of Biophysics and Nuclear Medicine, 3rd, Medical Faculty Charles University, Prague, Czechoslovakia.
Vrána
A
A
Výmola
F
F
Krylová
M
M
D000818:Animals; D001770:Blood Bactericidal Activity / Q000528:radiation effects*; D001804:Blood Transfusion, Autologous; D011817:Rabbits; D013203:Staphylococcal Infections / Q000628:therapy*; D013211:Staphylococcus aureus; D013997:Time Factors; D014466:Ultraviolet Rays