title: Genetic stability of the antagonistic character of Enterococcus faecalis ssp. liquefaciens and the detection of a new inhibitory bacteriocin-like substance.
abstract: The inhibitory capacity of strain S-48 of Enterococcus faecalis ssp. liquefaciens was studied. The strain produces a broad-spectrum peptide antibiotic (AS-48) that has been characterized elsewhere. The isolation of mutants from S-48 after mutagenic treatment revealed another inhibitory substance which remained masked in the wild strain. The protein nature and restricted spectrum of this substance points to its being a bacteriocin.
authors.affiliation: Departamento de Microbiología, Facultad de Ciencias, Universidad de Granada, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Martínez-Bueno
authors.forename: A
authors.initials: A
authors.lastname: Gálvez
authors.forename: M
authors.initials: M
authors.lastname: Maqueda
authors.forename: E
authors.initials: E
authors.lastname: Valdivia
mesh_terms: D000165:Acridine Orange / Q000494:pharmacology; D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D001430:Bacteriocins / Q000302:isolation & purification* / Q000494:pharmacology; D013293:Enterococcus faecalis / Q000032:analysis / Q000187:drug effects / Q000235:genetics*; D004926:Escherichia coli / Q000187:drug effects; D004996:Ethidium / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010455:Peptides / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D001430:Bacteriocins; D010455:Peptides; C065279:bacteriocin Bc 48; C051034:BacA protein, Enterococcus faecalis; D004996:Ethidium; D000165:Acridine Orange