Role of autocrine stimulation in a glioma cell line.
It has recently been shown that autocrine stimulation can play a pivotal role in the development and progression of a variety of neoplasms, including malignant gliomas. In this paper is reported how a glioma cell is able to be stimulated by basic fibroblast growth factor (bFGF) and, at the same time, to produce a growth factor which shares with bFGF many biological and biochemical properties.
Maleci
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Dipartimento di Science Neurologiche, Neurochirurgia, Università degli Studi di Roma La Sapienza, Italy.
D002455:Cell Division / Q000502:physiology; D016222:Fibroblast Growth Factor 2 / Q000096:biosynthesis*; D005910:Glioma / Q000378:metabolism* / Q000473:pathology; D014407:Tumor Cells, Cultured
D016222:Fibroblast Growth Factor 2