title: Role of somatic mutation in atherosclerosis.
abstract: Thus, plaque DNAs from two widely different classes of organisms exhibit similar molecular alterations, which are comparable to those previously described for a number of tumor DNAs. These findings represent the first direct demonstration that mutational events may be critical in the etiology of arteriosclerotic plaques.
authors.affiliation: Department of Environmental Medicine, New York University Medical Center, NY 10016.
authors.forename: A
authors.initials: A
authors.lastname: Penn
mesh_terms: D000818:Animals; D001161:Arteriosclerosis / Q000209:etiology / Q000235:genetics*; D002273:Carcinogens; D002999:Clone Cells / Q000473:pathology; D006801:Humans; D009130:Muscle, Smooth / Q000473:pathology; D009154:Mutation; D009374:Neoplasms, Experimental / Q000235:genetics; D014162:Transfection; D014780:Viruses / Q000472:pathogenicity
chemical_list: D002273:Carcinogens