Advantages of a new anticoagulant in routine hematology on the Coulter Counter S-Plus STKR analyzer.
The authors report the advantages of a new anticoagulant-antiaggregant mixture that avoids the deleterious effects of ethylenediaminotetraacetic acid (EDTA) on mean platelet volume and also prevents EDTA-induced platelet clumping. It is suitable for routine cell counting and sizing with the Coulter Counter S-Plus STKR. The values of the common hematologic parameters agree well with those from EDTA-treated samples and are stable for at least eight hours after sampling.
Lippi
U
U
Laboratorio di Chimica Clinica ed Ematologia, Ospedale Maggiore, Verona, Italy.
Schinella
M
M
Modena
N
N
Nicoli
M
M
Lippi
G
G
D000925:Anticoagulants / Q000494:pharmacology*; D001772:Blood Cell Count / Q000295:instrumentation*; D001792:Blood Platelets / Q000187:drug effects; D002951:Citrates / Q000494:pharmacology*; D004338:Drug Combinations / Q000494:pharmacology; D004492:Edetic Acid / Q000494:pharmacology; D006801:Humans; D010974:Platelet Aggregation / Q000187:drug effects; D010976:Platelet Count / Q000295:instrumentation; D011732:Pyridoxal Phosphate / Q000494:pharmacology*; D012016:Reference Values; D014325:Tromethamine / Q000494:pharmacology*
D000925:Anticoagulants; D002951:Citrates; D004338:Drug Combinations; C064185:pyridoxal phosphate, trisodium citrate, tromethamine drug combination; D014325:Tromethamine; D011732:Pyridoxal Phosphate; D004492:Edetic Acid