title: Molecular and developmental characterization of the heat shock cognate 4 gene of Drosophila melanogaster.
abstract: The Drosophila heat shock cognate gene 4 (hsc4), a member of the hsp70 gene family, encodes an abundant protein, hsc70, that is more similar to the constitutively expressed human protein than the Drosophila heat-inducible hsp70. Developmental expression revealed that hsc4 transcripts are enriched in cells active in endocytosis and those undergoing rapid growth and changes in shape.
authors.affiliation: Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115.
authors.forename: L A
authors.initials: LA
authors.lastname: Perkins
authors.forename: J S
authors.initials: JS
authors.lastname: Doctor
authors.forename: K
authors.initials: K
authors.lastname: Zhang
authors.forename: L
authors.initials: L
authors.lastname: Stinson
authors.forename: N
authors.initials: N
authors.lastname: Perrimon
authors.forename: E A
authors.initials: EA
authors.lastname: Craig
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004331:Drosophila melanogaster / Q000196:embryology / Q000235:genetics*; D004625:Embryo, Nonmammalian / Q000502:physiology; D005091:Exons; D005796:Genes; D006360:Heat-Shock Proteins / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D005810:Multigene Family; D015183:Restriction Mapping; D012689:Sequence Homology, Nucleic Acid; D014158:Transcription, Genetic
chemical_list: D006360:Heat-Shock Proteins