Treatment of endometriosis with gonadotropin releasing hormone agonist (buserelin).
The results of treatment of endometriosis with intranasal buserelin is convincing. The drug effectively suppresses serum estradiol to the menopausal level. Clinical improvement and regression of endometriotic lesions were observed during treatment. Thus, buserelin offers an alternative medical treatment of endometriosis. Further studies of the effects of GnRH agonist on bone mass are needed.
Sirimongkolkasem
R
R
Department of Obstetrics & Gynaecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Rojanasakul
A
A
Chailurkit
L O
LO
D000328:Adult; D002064:Buserelin / Q000627:therapeutic use*; D004715:Endometriosis / Q000097:blood / Q000188:drug therapy*; D004958:Estradiol / Q000097:blood; D005260:Female; D006065:Gonadotropins, Pituitary / Q000097:blood; D006801:Humans; D011374:Progesterone / Q000097:blood; D014594:Uterine Neoplasms / Q000097:blood / Q000188:drug therapy*
D006065:Gonadotropins, Pituitary; D011374:Progesterone; D004958:Estradiol; D002064:Buserelin