title: [Treatment-effect on cyclosporin A-induced gingival hyperplasia in patients with organ transplantation: a longitudinal study].
abstract: In the present study a newly developed concept for avoiding recurrences after the periodontal surgical treatment of cyclosporin A-induced gingival hyperplasia is described. Conventional gingivectomy results in restitutio per secundam, which promotes recurrences. To avoid this we tried to achieve a restitutio per primam by using a modified surgical technique. Ten patients, four treated under general anesthesia and six on an outpatient basis, were treated with this technique. Patients were monitored for 20 month. Pre- and postoperative care was performed in a standardized manner for all patients. During the surveillance, a long-term suppression of the cyclosporin-induced gingival hyperplasia could be found, but it was not possible to avoid recurrences totally.
authors.affiliation: Zentrum Zahn-, Mund- und Kieferheilkunde Medizinische Hochschule Hannover.
authors.forename: H
authors.initials: H
authors.lastname: Günay
authors.forename: B G
authors.initials: BG
authors.lastname: Evers
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003524:Cyclosporins / Q000009:adverse effects*; D005260:Female; D005885:Gingival Hyperplasia / Q000139:chemically induced / Q000628:therapy*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D016377:Organ Transplantation / Q000009:adverse effects*
chemical_list: D003524:Cyclosporins
vernacular_title: Behandlungseffekt auf Cyclosporin-A-induzierte Gingivahyperplasien bei organtransplantierten Patienten--Eine Verlaufskontrolle.