Diet restriction decreases the membrane microviscosity of cerebellar membranes of old female Wistar rats.
The microviscosity of cerebellar membranes from female Wistar rats during aging and subsequent to diet restriction has been investigated. Diet restriction was applied feeding the animals on every-other-day schedule starting from the age of 3.5 months. Undernutrition increased the lifespan of the animals and retarded the appearance of the age-dependent increase of microviscosity of cerebellar membranes.
Pieri
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Cytology Center, Gerontological Research Department on I.N.R.C.A., Ancona, Italy.
Moroni
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F
Falasca
F
F
Marcheselli
F
F
Recchioni
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R
D000375:Aging / Q000502:physiology*; D000818:Animals; D002462:Cell Membrane / Q000648:ultrastructure*; D002531:Cerebellum / Q000648:ultrastructure*; D005260:Female; D005508:Food Deprivation / Q000502:physiology*; D015227:Lipid Peroxidation; D008563:Membrane Lipids / Q000032:analysis; D010084:Oxidation-Reduction; D051381:Rats; D011919:Rats, Inbred Strains / Q000502:physiology*; D014783:Viscosity
D008563:Membrane Lipids