[The use of genetic engineering in veterinary medicine with examples from epidemiology, diagnosis and drug production].
The results of genetic engineering have reached practical veterinary medicine already. Nevertheless there is a great lack of knowledge among those veterinarians who usually do not work with these methods. Therefore we want to give an introduction into the advantages and dangers of this technology concerning veterinary medicine. Some important analytical methods are explained. Related viruses such as WEE and EEE or canine parvovirus, feline parvovirus and mink enteritis virus, or the related coronaviruses FIPV and TGEV serve as examples for the possibilities in molecular diagnosis and epidemic monitoring. The history of the gl- mutants of PRV, now prescribed as vaccine strains in the FRG, is an example of the development of genetic engineered vaccines. A new generation of vaccines based on recombinant vaccinia viruses is imminent. Thus we have to be aware of the high risks and responsibility of everybody who is involved in these new systems, especially the scientist who produces genetically altered organisms.
Mayr
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A
Institut für Medizinische Mikrobiologie, Fakultät der Ludwig-Maximilians-Universität München.
Hübert
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P
D000818:Animals; D005818:Genetic Engineering; D011994:Recombinant Proteins / Q000096:biosynthesis; D014612:Vaccines; D014614:Vaccines, Synthetic; D014730:Veterinary Medicine; D014777:Virus Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000662:veterinary*; D014780:Viruses / Q000235:genetics*
D011994:Recombinant Proteins; D014612:Vaccines; D014614:Vaccines, Synthetic
Uber den Nutzen der Gentechnologie in der Tiermedizin an den Beispielen Epidemiologie, Diagnose und Arzneimittelherstellung.