title: Group A variants defined with a monoclonal anti-A reagent.
abstract: Unusual serologic findings mimicking the B(A) phenomenon were noted in two group B blood donors using blended murine monoclonal anti-A reagent. With additional studies, including a binding experiment using affinity chromatography, the presence of aberrant group A activities was confirmed. This observation suggests that persons with atypical B(A) phenotype may warrant further investigation to delineate the ABO blood group.
authors.affiliation: American Red Cross Blood Services, Northwest Ohio Region, Toledo.
authors.forename: P
authors.initials: P
authors.lastname: Lau
authors.forename: S
authors.initials: S
authors.lastname: Sererat
authors.forename: J
authors.initials: J
authors.lastname: Beatty
authors.forename: R
authors.initials: R
authors.lastname: Oilschlager
authors.forename: J
authors.initials: J
authors.lastname: Kini
mesh_terms: D000017:ABO Blood-Group System / Q000235:genetics* / Q000276:immunology; D000328:Adult; D000911:Antibodies, Monoclonal; D001782:Blood Donors; D001788:Blood Grouping and Crossmatching / Q000379:methods*; D002846:Chromatography, Affinity; D005700:Galactosyltransferases / Q000097:blood; D014644:Genetic Variation; D006386:Hemagglutination Tests; D006801:Humans; D007202:Indicators and Reagents; D008297:Male; D017350:N-Acetylgalactosaminyltransferases
chemical_list: D000017:ABO Blood-Group System; D000911:Antibodies, Monoclonal; D007202:Indicators and Reagents; D005700:Galactosyltransferases; D017350:N-Acetylgalactosaminyltransferases; C003742:UDPgalactosamine-galactose acetylgalactosaminyltransferase