Immunohistochemical investigations in epidermal Merkel cells--a common phenotype with eccrine sweat gland epithelium.
Mono- and polyclonal antibodies were used for immunofluorescence investigations in cytoskeletal and associated antigens on frozen sections of adult human skin. Epidermal Merkel cells were identified in the stratum basale. Their phenotype was compared with other epithelial cells of human skin. The inner duct epithelium of eccrine sweat glands showed an immunoreactivity similar to that of epidermal Merkel cells. A common origin of both cell types is suggested.
Wollina
U
U
Department of Dermatology, Friedrich Schiller University, Jena, GDR.
D000906:Antibodies; D000911:Antibodies, Monoclonal; D004439:Eccrine Glands / Q000032:analysis / Q000166:cytology*; D000078404:Epidermal Cells; D004817:Epidermis / Q000032:analysis; D004847:Epithelial Cells; D006801:Humans; D007150:Immunohistochemistry; D010641:Phenotype; D012867:Skin / Q000166:cytology; D013545:Sweat Glands / Q000166:cytology*
D000906:Antibodies; D000911:Antibodies, Monoclonal