title: Biosynthesis of prostaglandins in ovarian follicles and corpus luteum of sheep ovary.
abstract: The biosynthetic potential of prostaglandins (PGs) was measured in ovarian follicles and corpus luteum of sheep ovary. The total prostaglandins formed under non-enzymatic conditions were much lower in comparison to that formed using native GSTs. When the GSTs of ovarian follicles were employed, the major prostaglandin formed was PGE2 (81.22%) followed by PGD2 (16.9%) and PGF2 alpha (1.87%). In case of corpus luteum, prostaglandin formed was PGF2 alpha (59.01%). Since PGF2 alpha was demonstrated to be the luteolytic factor, the present study indicates the formation of luteolytic factor in the ovarian tissue itself.
authors.affiliation: Department of Zoology, Sri Venkateswara University, Tirupati, India.
authors.forename: O
authors.initials: O
authors.lastname: Padmavathi
authors.forename: G P
authors.initials: GP
authors.lastname: Reddy
authors.forename: G R
authors.initials: GR
authors.lastname: Reddy
authors.forename: P
authors.initials: P
authors.lastname: Reddanna
mesh_terms: D000818:Animals; D003338:Corpus Luteum / Q000378:metabolism*; D005260:Female; D005982:Glutathione Transferase / Q000302:isolation & purification / Q000378:metabolism; D008297:Male; D006080:Ovarian Follicle / Q000378:metabolism*; D011451:Prostaglandin-Endoperoxide Synthases / Q000302:isolation & purification / Q000378:metabolism; D011453:Prostaglandins / Q000096:biosynthesis*; D012669:Seminal Vesicles / Q000201:enzymology; D012756:Sheep
chemical_list: D011453:Prostaglandins; D011451:Prostaglandin-Endoperoxide Synthases; D005982:Glutathione Transferase