title: [Pupil--recent development of investigation].
abstract: This paper introduces recent development of investigation in the pupil system, in the Department of Ophthalmology, Kitasato University. Firstly, normal pupil parameters among various age groups (10 years to 70 years old) were studied by a new infrared videopupillography (Iriscorder C-2515). The parameters studied were pupil area in darkness, and other various parameters followed by photic stimulation (3000 troland) of the eye. Secondly, the pupil was studied by photographic method using infrared film under ordinary illuminated (500-800 Lux) room, and drug response especially pilocarpine of the pupil was studied and reviewed. Thirdly, a new information about pupil response followed by 0.06% pilocarpine instillation in patients under the brain death has been proposed. Denervation supersensitivity was obvious in 70% of the patient under brain death. Clinical significance of this pharmacological study has been emphasized especially for the determination of the brain death under comatose state of a given patient.
authors.affiliation: Department of Ophthalmology, School of Medicine, Kitasato University.
authors.forename: S
authors.initials: S
authors.lastname: Ishikawa
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging; D001926:Brain Death / Q000175:diagnosis / Q000503:physiopathology*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010775:Photic Stimulation; D010862:Pilocarpine / Q000494:pharmacology; D011680:Pupil / Q000187:drug effects / Q000502:physiology*
chemical_list: D010862:Pilocarpine