title: The mechanism of action of interleukin-1: a cytokine acting through glycosyl-phosphatidylinositol hydrolysis?
authors.affiliation: Department of Human Metabolism and Clinical Biochemistry, University of Sheffield Medical School, U.K.
authors.forename: P R
authors.initials: PR
authors.lastname: Dobson
authors.forename: B L
authors.initials: BL
authors.lastname: Brown
mesh_terms: D000818:Animals; D004075:Diglycerides / Q000096:biosynthesis*; D004789:Enzyme Activation / Q000187:drug effects; D005347:Fibroblasts / Q000187:drug effects / Q000378:metabolism; D019204:GTP-Binding Proteins / Q000502:physiology*; D006868:Hydrolysis; D007375:Interleukin-1 / Q000494:pharmacology*; D051379:Mice; D010716:Phosphatidylinositols / Q000378:metabolism*; D011134:Polysaccharides / Q000378:metabolism*; D015290:Second Messenger Systems; D014407:Tumor Cells, Cultured / Q000187:drug effects / Q000378:metabolism; D010738:Type C Phospholipases / Q000378:metabolism; D010566:Virulence Factors, Bordetella / Q000494:pharmacology
chemical_list: D004075:Diglycerides; D007375:Interleukin-1; D010716:Phosphatidylinositols; D011134:Polysaccharides; D010566:Virulence Factors, Bordetella; D010738:Type C Phospholipases; D019204:GTP-Binding Proteins