[Turner's syndrome and autoimmune dysthyroidism].
The authors report a case of Turner's syndrome associated with Hashimoto's thyroiditis and present the various physiopathological hypotheses currently offered to explain the frequent association of an autoimmune pathology and a gonadal dysgenesis with an absence of X chromosome which is held responsible for autoimmunity. Is the chromosomal abnormality a factor predisposing to autoimmunity or does it result from a disturbance of the immune mechanism? Environmental factors, such as bacteria, viruses or some pollutants might be responsible for both the immune disorders and the chromosomal abnormality. The association of the two types of disease may also be accidental. In the present state of our knowledge, there is no answer to these questions.
Ortéga
F
F
Service d'Endocrinologie, CHU, Nancy.
Guérin
V
V
Créa
T
T
Hartemann
P
P
D000328:Adult; D005260:Female; D006801:Humans; D013967:Thyroiditis, Autoimmune / Q000150:complications* / Q000235:genetics / Q000276:immunology; D014424:Turner Syndrome / Q000150:complications* / Q000235:genetics / Q000276:immunology
Syndrome de Turner et dysthyroïdies auto-immunes.