[Transcatheter intra-arterial injection of combination drugs in case of advanced uterine cervical cancer].
A total of 10 uterine cervical cancer patients (stage IIb 2, stage IIIb 6, stage IVb 2) were treated two times with selective intra-arterial injection of combined drugs of CDDP, ADR, 5-FU, MMC before operation or radiation therapy. In all patients, the tumor size was reduced macroscopically as well as on MR images. The tumor marker SCC was decreased after TAI. In 7 cases (IIb 2, IIIb 4, IVb 1) surgical treatment was made about 1 month after TAI. Histological examinations revealed that the cancer invasion markedly reduced and no malignant cells found in 3 patients.
Kinashi
Y
Y
Department of Radiology, Faculty of Medicine, Kyoto University.
Nagata
Y
Y
Abe
M
M
Honda
T
T
Takai
I
I
Tai
S
S
Mori
T
T
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000473:pathology; D002945:Cisplatin / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007269:Injections, Intra-Arterial; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy* / Q000473:pathology
D008937:Mitomycins; D016685:Mitomycin; D004317:Doxorubicin; D002945:Cisplatin