Chronic lymphocytic leukemia in a patient with systemic lupus erythematosus.
We report the development of chronic lymphocytic leukemia in a 48-year-old woman with systemic lupus erythematosus of 5 years' duration. Although the association of autoimmunity and lymphoreticular malignancy is well known, this particular association has only rarely been reported. Possible mechanisms of pathogenesis are discussed.
Lishner
M
M
Department of Medicine, Mount Sinai Hospital, Canada.
Hawker
G
G
Amato
D
D
D002908:Chronic Disease; D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000097:blood / Q000209:etiology* / Q000276:immunology; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000150:complications* / Q000276:immunology; D008875:Middle Aged