High-performance liquid chromatographic analysis of chlorambucil tert.-butyl ester and its active metabolites chlorambucil and phenylacetic mustard in plasma and tissue.
Greig
N H
NH
Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892.
Stahle
P L
PL
Shetty
H U
HU
Genka
S
S
John
V
V
Soncrant
T T
TT
Rapoport
S I
SI
D000818:Animals; D001921:Brain / Q000378:metabolism; D002699:Chlorambucil / Q000031:analogs & derivatives* / Q000032:analysis* / Q000097:blood / Q000378:metabolism / Q000493:pharmacokinetics; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation; D005260:Female; D009588:Nitrogen Mustard Compounds / Q000032:analysis* / Q000097:blood / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012044:Regression Analysis
D009588:Nitrogen Mustard Compounds; C008826:phenacid; C063211:chlorambucil-tertiary butyl ester; D002699:Chlorambucil