Multiple transient ischaemic attacks and a mild thrombotic stroke in a HIV-positive patient with anticardiolipin antibodies.
Antiphospholipid antibodies (APA) have been reported to be associated with thrombosis in systemic lupus erythematosus (SLE) and in many other clinical groups. However, although these antibodies have been identified in a substantial number of patients infected with the human immunodeficiency virus (HIV), in this case an association with thrombosis has not been evident. We describe a patient with HIV infection who had anticardiolipin antibodies (ACA) but no lupus anticoagulant (LA) who had recurrent transient ischaemic attacks (TIAs) and a mild stroke.
Keeling
D M
DM
Department of Haematology, University College and Middlesex School of Medicine, London, UK.
Birley
H
H
Machin
S J
SJ
D000328:Adult; D001323:Autoantibodies / Q000097:blood*; D002308:Cardiolipins / Q000276:immunology*; D005260:Female; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000150:complications*; D002546:Ischemic Attack, Transient / Q000150:complications*
D001323:Autoantibodies; D002308:Cardiolipins