MR imaging of optic nerve lesions: value of gadopentetate dimeglumine and fat-suppression technique.
Eleven patients with known or suspected optic nerve lesions and eight normal subjects were examined with spin-echo technique at 1.5 T with unenhanced T1-weighted imaging, IV gadopentetate-dimeglumine-enhanced T1-weighted imaging, and enhanced T1-weighted imaging with fat suppression. Two pathologically proved and four presumed optic nerve meningiomas demonstrated significant enhancement and were best seen with the fat-suppression technique. None of the three presumed optic nerve gliomas nor the optic nerves of normal subjects demonstrated qualitative enhancement. We conclude that the use of a fat-suppression technique with gadopentetate dimeglumine enhancement improves delineation of enhancing optic nerve lesions. This technique should be useful for evaluating other anatomic regions where enhancing tissue marginates fat.
Hendrix
L E
LE
Department of Radiology, Medical College of Wisconsin, Froedtert Memorial Lutheran Hospital, Milwaukee 53226.
Kneeland
J B
JB
Haughton
V M
VM
Daniels
D L
DL
Szumowski
J
J
Williams
A L
AL
Mark
L P
LP
Czervionke
L F
LF
D000273:Adipose Tissue / Q000473:pathology; D000328:Adult; D000368:Aged; D003390:Cranial Nerve Neoplasms / Q000175:diagnosis*; D019786:Gadolinium DTPA; D005910:Glioma / Q000175:diagnosis; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging; D008579:Meningioma / Q000175:diagnosis; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000175:diagnosis*; D009942:Organometallic Compounds; D004369:Pentetic Acid
D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA