Unsaturated fatty acids and viability of Helicobacter (Campylobacter) pylori.
Helicobacter (Campylobacter) pylori was found to be sensitive to the toxic effects of an unsaturated fatty acid (arachidonic acid). Data are presented that support the hypothesis that exogenous catalase added to basal media enhances the growth of H. pylori by preventing the formation of toxic peroxidation products from long-chain unsaturated fatty acids.
Hazell
S L
SL
Department of Medicine, Veterans Affairs Medical Center, Houston, Texas.
Graham
D Y
DY
D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000494:pharmacology*; D002167:Campylobacter / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D002374:Catalase / Q000378:metabolism / Q000494:pharmacology; D003470:Culture Media; D004352:Drug Resistance, Microbial; D005231:Fatty Acids, Unsaturated / Q000378:metabolism; D006801:Humans
D001095:Arachidonic Acids; D003470:Culture Media; D005231:Fatty Acids, Unsaturated; D016718:Arachidonic Acid; D002374:Catalase