Oligomerization of cytosine-containing nucleotide analogs in aqueous solution.
Bisphosphoimidazolides of 2'-deoxycytidine and of its acyclic analog C can be oligomerized in aqueous solution in the presence of Mn(II). Under certain conditions, a range of products extending to at least the 20mer can be obtained. These products are of interest as possible templates for oligomerization of the complementary monomers.
Visscher
J
J
Faculty of Science, University of Nijmegen, The Netherlands.
Schwartz
A W
AW
D005075:Biological Evolution; D002384:Catalysis; D003841:Deoxycytidine; D008274:Magnesium; D009841:Oligonucleotides
D009841:Oligonucleotides; D003841:Deoxycytidine; D008274:Magnesium