Allyl protection of O6 position of 2'-deoxyguanosine.
Allyl serves as the protecting group for O6 position of guanosine. The deblocking is easily performed by brief treatment with a palladium(O) catalyst and a nucleophile.
Hayakawa
Y
Y
Department of Chemistry, College of General Education, Faculty of Science, Nagoya University, Japan.
Hirose
M
M
Noyori
R
R
D000433:1-Propanol / Q000737:chemistry; D003849:Deoxyguanosine / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D015394:Molecular Structure; D010100:Oxygen / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry; D020005:Propanols
D020005:Propanols; C006463:allyl alcohol; D010165:Palladium; D000433:1-Propanol; D003849:Deoxyguanosine; D010100:Oxygen