[The determination of allergen-specific IgE and IgG antibodies in patients sensitized to the house dust mite Dermatophagoides pteronyssinus].
45 patients, hypersensitive to house-dust mites, were examined by the method of skin tests to D. pteronyssinus allergen. Besides, in their blood sera the levels of allergen-specific IgE antibodies were determined in the radioallergosorbent test and allergen-specific IgG antibodies, in the enzyme immunoassay. These tests revealed that in 91% of the patients the results of skin tests were positive, in 68% an elevated level of specific IgE antibodies and in 93% of the patients an elevated level of specific IgG antibodies were detected. All patients showed the positive result in one of the above-mentioned tests. The largest group of the patients (55%) included persons showing the positive result of the skin test and having elevated levels of allergen-specific IgG and IgE antibodies. Thus, in cases of hypersensitivity to house-dust mites the levels of allergen-specific IgG and IgE antibodies in the patients' blood sera should be determined.
Golysheva
M A
MA
Glikman
M V
MV
Berzhets
V M
VM
Prilepina
T A
TA
Pakhomova
L A
LA
D000293:Adolescent; D000328:Adult; D000485:Allergens / Q000276:immunology*; D000818:Animals; D000918:Antibody Specificity; D004391:Dust; D006801:Humans; D007114:Immunization; D007073:Immunoglobulin E / Q000032:analysis*; D007074:Immunoglobulin G / Q000032:analysis*; D008875:Middle Aged; D008925:Mites / Q000276:immunology*; D012882:Skin Tests
D000485:Allergens; D004391:Dust; D007074:Immunoglobulin G; D007073:Immunoglobulin E
Opredelenie allergenspetsificheskikh IgE- i IgG-antitel u bol'nykh s sensibilizatsieĭ k kleshcham domashneĭ pyli Dermatophagoides pteronyssinus.