title: Lack of transmission of HIV to sexual and non-sexual contacts to HIV seropositive haemophiliacs following preventive information.
abstract: In order to evaluate the risk of HIV transmission to sexual and non-sexual contacts to seropositive haemophiliacs, HIV antibodies, p24 antigen, immunoglobulin levels and lymphocyte subsets were analyzed in a cohort of Swedish haemophiliac families to 19 patients who seroconverted in 1980-82. As controls served contacts to 26 seronegative haemophiliacs. A total of 77 contacts were investigated. Except for 3 sexual partners who had seroconverted before 1985 no signs of HIV infection were detected. It was concluded that no HIV transmission occurred to household contacts of seropositive haemophiliacs and that transmission to heterosexual partners not appeared since 1985 when the patients and their families were informed about the risk of infection.
authors.affiliation: Department of Coagulation Disorders, University of Lund, Malmö General Hospital, Sweden.
authors.forename: E
authors.initials: E
authors.lastname: Berntorp
authors.forename: P
authors.initials: P
authors.lastname: Christensen
authors.forename: K
authors.initials: K
authors.lastname: Lindvall
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D015683:Gene Products, gag / Q000097:blood / Q000276:immunology; D015483:HIV Antibodies / Q000097:blood; D015488:HIV Antigens / Q000097:blood; D016655:HIV Core Protein p24; D015658:HIV Infections / Q000150:complications / Q000517:prevention & control / Q000635:transmission*; D006679:HIV Seropositivity / Q000150:complications / Q000635:transmission*; D006467:Hemophilia A / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D014758:Viral Core Proteins / Q000097:blood / Q000276:immunology
chemical_list: D015683:Gene Products, gag; D015483:HIV Antibodies; D015488:HIV Antigens; D016655:HIV Core Protein p24; D014758:Viral Core Proteins