Hypoproteinemia related with chronic lithium therapy in two patients.
We present here two cases of reversible hypoproteinemia which could have occurred as an adverse effect of chronic lithium administration. In the present cases, protein losing a renal dysfunction, liver dysfunction and malabsorption syndrome were not observed, and the relationship between their dietary volume and serum protein levels was poor. The mechanism of hypoproteinemia in these cases was not identified from previously obtained data. We suggested that this type of hypoproteinemia might be a new adverse effect of lithium.
Fukue
M
M
Department of Neurology and Psychiatry, Fukuyama National Hospital, Hiroshima, Japan.
Nakahara
T
T
Sarai
K
K
D000328:Adult; D000368:Aged; D001714:Bipolar Disorder / Q000188:drug therapy; D005260:Female; D006801:Humans; D007019:Hypoproteinemia / Q000139:chemically induced*; D008094:Lithium / Q000009:adverse effects* / Q000097:blood; D016651:Lithium Carbonate
D016651:Lithium Carbonate; D008094:Lithium