Does a tetracycline resistance determinant of class N exist?
pMV120 was reported to carry the tetracycline resistance (Tcr) determinant of class N. We obtained tetracycline-susceptible transconjugants harboring plasmids with restriction enzyme profiles indistinguishable from those of pMV120 isolated from tetracycline-resistant clones. We conclude that pMV120 is a cryptic plasmid and that class N of Tcr determinants does not exist.
Horaud
T
T
Laboratoire des Staphylocoques et des Streptocoques, Institut Pasteur, Paris, France.
Delbos
F
F
Pepper
K
K
D003001:Cloning, Molecular; D013293:Enterococcus faecalis / Q000187:drug effects / Q000235:genetics; D008826:Microbial Sensitivity Tests; D010957:Plasmids; D013752:Tetracycline / Q000494:pharmacology*; D013753:Tetracycline Resistance
D013752:Tetracycline