[Effects of radix Salviae Miltiorrhizae on visceral pain discharges in the posterior nucleus of the thalamus in cats].
Extracellular microelectrode method and stereotaxic technique of brain were used to investigate the effects of Radix Salviae Miltiorrhizae on the discharges of visceral pain in the posterior nucleus of thalamus(po)in cats. Experiments showed that Radix Salvia Miltiorrhizae inhibited the discharges of visceral pain in po, Radix Salviae Miltiorrhizae acts directly on the peripheral nerve trunk and cannot block its exciting conduction. This suggests that the analgesic effect of Radix Salviae Miltiorrhizae is exerted via central nervous system.
Liu
C
C
Department of Internal Medicine, China Air Force, Dalian Hospital.
Shi
W
W
Sun
L
L
Zheng
Q
Q
D000700:Analgesics; D000818:Animals; D002023:Bufo bufo; D002415:Cats; D004338:Drug Combinations / Q000494:pharmacology; D004365:Drugs, Chinese Herbal; D004558:Electric Stimulation; D005071:Evoked Potentials / Q000187:drug effects; D005260:Female; D008297:Male; D009619:Nociceptors / Q000502:physiology; D010525:Peripheral Nerves / Q000502:physiology; D010618:Phenanthrolines / Q000494:pharmacology*; D010936:Plant Extracts; D027561:Salvia miltiorrhiza; D013153:Splanchnic Nerves / Q000502:physiology*; D013787:Thalamic Nuclei / Q000502:physiology*
D000700:Analgesics; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D010618:Phenanthrolines; D010936:Plant Extracts; C028972:dan-shen root extract