title: Ischemic heart disease and regional left ventricular wall motion: a study comparing radial, centerline and a video intensity based slope technique.
abstract: Left ventricular regional wall motion in ischemic heart disease was evaluated and compared using three different methods based on radiographic ventriculograms. Radial method uses an internal reference system, and centerline method employs an external reference system, both methods are based on two frame analysis. The last method, an automated video intensity technique, analyzes on a frame by frame basis utilizing an external reference system. A total of 42 patients were included in the study, of these 12 had a history of myocardial infarction. Significant coronary artery stenosis was defined as 50% measured diameter reduction. Right coronary artery (29/42) was most commonly involved. Single vessel disease was present in 18 patients, two vessel disease in 15 and three vessel disease in eight patients. The radial method detected abnormal wall motion in 16/42 patients, centerline method yielded a detection accuracy of 22/42 and with the new technique, asynchrony was noted in 39/42 patients. All three methods detected regional wall motion abnormalities with a higher sensitivity in patients with prior myocardial infarction. The centerline method had highest sensitivity for the right coronary artery bed (55%). The radial method (45%) and the video intensity based technique (95%) had the highest sensitivity for regions supplied by the left anterior descending artery.
authors.affiliation: Department of Medicine, University of California, San Diego.
authors.forename: K S
authors.initials: KS
authors.lastname: Sunnerhagen
authors.forename: S C
authors.initials: SC
authors.lastname: Smith
authors.forename: B E
authors.initials: BE
authors.lastname: Jaski
authors.forename: V
authors.initials: V
authors.lastname: Bhargava
mesh_terms: D000368:Aged; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000503:physiopathology*; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008297:Male; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000503:physiopathology; D011859:Radiography; D012680:Sensitivity and Specificity; D016277:Ventricular Function, Left / Q000502:physiology*