Growth inhibition in vitro of Mycobacterium smegmatis by ten N-aryl glycyl hydrazides.
N-(4-amino-2-nitro-toluinyl) glycyl hydrazide and N-(biphenyl) glycyl hydrazide partially inhibited the growth of M smegmatis at 20 micrograms/ml and showed a total inhibition at 100 micrograms/ml. Replacement by a nitro or halogen group lowered the activity.
Beri
R
R
Department of Chemistry, University of Delhi, India.
Chandra
R
R
Murti
V V
VV
D001713:Biphenyl Compounds / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D006834:Hydrazines / Q000494:pharmacology*; D009161:Mycobacterium / Q000187:drug effects*
D001713:Biphenyl Compounds; D006834:Hydrazines; C070876:N-(biphenyl)glycylhydrazide; C070875:N-(4-amino-2-nitrotoluinyl)glycylhydrazide