title: Imaging cells with the atomic force microscope.
abstract: Different types of cells have been imaged with the atomic force microscope. The morphology of the archaebacterium Halobacterium halobium in its dry state was revealed. On a leaf of the small Indian tree Lagerstroemia subcostata a stoma was imaged. The lower side of a water lily leaf was imaged in water showing features down to 12 nm. Finally, fixed red and white blood cells were imaged in buffer showing features down to 8 nm. The images demonstrate that atomic force microscopy can provide high-resolution images of cell surfaces under physiological conditions.
authors.affiliation: Department of Physics, University of California, Santa Barbara 93106.
authors.forename: H J
authors.initials: HJ
authors.lastname: Butt
authors.forename: E K
authors.initials: EK
authors.lastname: Wolff
authors.forename: S A
authors.initials: SA
authors.lastname: Gould
authors.forename: B
authors.initials: B
authors.lastname: Dixon Northern
authors.forename: C M
authors.initials: CM
authors.lastname: Peterson
authors.forename: P K
authors.initials: PK
authors.lastname: Hansma
mesh_terms: D000818:Animals; D004912:Erythrocytes / Q000648:ultrastructure*; D006217:Halobacterium / Q000648:ultrastructure*; D008214:Lymphocytes / Q000648:ultrastructure*; D008853:Microscopy / Q000379:methods*; D010944:Plants / Q000648:ultrastructure*