[The oxidation of different substrates by liver mitochondria from rat pups in early postnatal development].
We have studied the respiratory ratio of liver mitochondria during oxidation of substrates of the carbohydrate and lipid metabolism in newborn rats and during early postnatal development. High rate of respiration coupled with the synthesis of ATP from ADP and phosphate has been found during oxidation of carbohydrate substrates (pyruvate + malate); however, caprilate, a substrate of lipid metabolism, does not support such respiration. However, in the young rats aging from 2 to 30 days utilization of carbohydrate and lipid substrates via the phosphorylating pathway proceeds with similar efficacy.
Akhmerov
R N
RN
Cherlin
V A
VA
Makhmudov
E S
ES
D000375:Aging / Q000378:metabolism*; D000818:Animals; D000831:Animals, Newborn; D050260:Carbohydrate Metabolism; D066298:In Vitro Techniques; D050356:Lipid Metabolism; D008930:Mitochondria, Liver / Q000201:enzymology*; D010084:Oxidation-Reduction; D010766:Phosphorylation; D051381:Rats; D011919:Rats, Inbred Strains; D013379:Substrate Specificity
Okislenie raznykh substratov mitokhondriiami pecheni krysiat v rannem postnatal'nom razvitii.