title: Field evaluation of measles vaccine efficacy in New Seemapuri, Shahdara Zone-Delhi during 1990.
abstract: A field evaluation of measles vaccine efficacy was undertaken in resettlement colonies in New Seemapuri, Shahdara Zone, Delhi, having an estimated population of 20,500 by case-reference method. The standard 30 cluster sampling technique was adopted and 261 measles vaccinated children were matched with 545 measles non-vaccinated children. The attack rate of measles was found to be 4.2 and 30.3 per cent in measles vaccinated and non-vaccinated children respectively, which is statistically highly significant (P less than 0.001). The relative risk of developing measles in non-vaccinated child is seven times more as compared to a vaccinated child. Vaccine efficacy (V.E.) evaluated by different epidemiological and laboratory methods was found to be 86.1 per cent +/- 11 at P = 0.05. Further, a large scale study on measles V.E. is recommended in different parts of the country by case-reference method, as it is found to be simple, reproducible and easy to undertake in a field situation.
authors.affiliation: National Institute of Communicable Diseases, Sham Nath Marg, Delhi.
authors.forename: U
authors.initials: U
authors.lastname: Chawla
authors.forename: S K
authors.initials: SK
authors.lastname: Benera
authors.forename: S
authors.initials: S
authors.lastname: Bandyopadhyay
authors.forename: B N
authors.initials: BN
authors.lastname: Chaudhary
authors.forename: O P
authors.initials: OP
authors.lastname: Gupta
authors.forename: R K
authors.initials: RK
authors.lastname: Khallendra
authors.forename: J
authors.initials: J
authors.lastname: Ramaswamy
authors.forename: S
authors.initials: S
authors.lastname: Khare
authors.forename: R S
authors.initials: RS
authors.lastname: Sharma
authors.forename: K K
authors.initials: KK
authors.lastname: Dutta
mesh_terms: D000914:Antibodies, Viral / Q000097:blood*; D002675:Child, Preschool; D006801:Humans; D007194:India; D007223:Infant; D008457:Measles / Q000517:prevention & control*; D008458:Measles Vaccine / Q000592:standards*; D008459:Measles virus / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D008458:Measles Vaccine