title: Effects of nerve agent antidote and heat exposure on soldier performance in the BDU and MOPP-IV ensembles.
abstract: This study assessed the effects of nerve agent antidote (atropine/2-PAM chloride versus saline placebo) and heat-humidity (95 degrees F/60% RH versus 70 degrees F/30% RH) on repeated performance of militarily relevant psychological tasks while wearing the battle dress uniform (BDU) and while wearing chemical protective clothing (MOPP-IV). All BDU heat sessions (6 hours) were completed, but with some task impairments and a few subjective reactions. MOPP-IV heat sessions could not be continued beyond 2 hours; all tasks were impaired and subjective reactions were numerous and severe. Atropine/2-PAM significantly shortened endurance time for heat sessions in MOPP-IV.
authors.forename: J L
authors.initials: JL
authors.lastname: Kobrick
authors.forename: R F
authors.initials: RF
authors.lastname: Johnson
authors.forename: D J
authors.initials: DJ
authors.lastname: McMenemy
mesh_terms: D000293:Adolescent; D000328:Adult; D000339:Affect; D000931:Antidotes / Q000009:adverse effects*; D001285:Atropine / Q000009:adverse effects*; D004359:Drug Therapy, Combination; D004526:Efficiency; D006359:Heat Exhaustion / Q000503:physiopathology* / Q000523:psychology; D006801:Humans; D008297:Male; D008889:Military Personnel / Q000523:psychology*; D011220:Pralidoxime Compounds / Q000009:adverse effects*; D011481:Protective Clothing / Q000592:standards*
chemical_list: D000931:Antidotes; D011220:Pralidoxime Compounds; D001285:Atropine; C028797:pralidoxime