[Residual hyperinsulinism after glucose oral load in obese subjects with normal glucose tolerance].
Forty-five NGT obese subjects were submitted to OGTT with IRI and CPR determinations and to euglycemic hyperinsulinemic clamp, and divided into two groups: A) those with return of insulinemia toward basal values, and B) those with residual hyperinsulinism, in order to evaluate possible differences in insulin secretion and/or insulin action among them. Our data show the younger age of those with residual hyperinsulinism, that also seems related to insulin secretion, represented by IRI and CPR basal values, but not to insulin resistance parameters.
Sinagra
D
D
Clinica Medica Base, Policlinico Universitario di Palermo.
Randazzo
C
C
Galluzzo
G
G
Mistretta
A
A
D000328:Adult; D005260:Female; D005947:Glucose; D005951:Glucose Tolerance Test; D006801:Humans; D006946:Hyperinsulinism / Q000097:blood*; D007328:Insulin / Q000097:blood; D008297:Male; D009765:Obesity / Q000097:blood*
D007328:Insulin; D005947:Glucose
Iperinsulinismo residuo dopo carico orale di glucosio in obesi a normale tolleranza glicidica.