Evidence that calcium mediates free radical damage through activation of phospholipase A2 during cold storage of the rabbit kidney.
Cotterill
L A
LA
Section of Surgical Research, Clinical Research Centre, Harrow, Middlesex, U.K.
Gower
J D
JD
Fuller
B J
BJ
Green
C J
CJ
D000818:Animals; D016718:Arachidonic Acid; D001095:Arachidonic Acids / Q000378:metabolism; D000001:Calcimycin / Q000494:pharmacology; D002118:Calcium / Q000502:physiology*; D002849:Chromatography, Gas; D002951:Citrates / Q000494:pharmacology; D003080:Cold Temperature; D003992:Dibucaine / Q000494:pharmacology; D004789:Enzyme Activation; D005230:Fatty Acids, Nonesterified / Q000378:metabolism; D005609:Free Radicals; D006982:Hypertonic Solutions; D066298:In Vitro Techniques; D007668:Kidney / Q000201:enzymology* / Q000378:metabolism; D007672:Kidney Cortex / Q000378:metabolism; D007679:Kidney Medulla / Q000378:metabolism; D009926:Organ Preservation; D010741:Phospholipases A / Q000378:metabolism*; D054467:Phospholipases A2; D011817:Rabbits
D001095:Arachidonic Acids; D002951:Citrates; D005230:Fatty Acids, Nonesterified; D005609:Free Radicals; D006982:Hypertonic Solutions; D016718:Arachidonic Acid; D000001:Calcimycin; D010741:Phospholipases A; D054467:Phospholipases A2; D003992:Dibucaine; D002118:Calcium