[Effect of Schistosoma mansoni infection on the immune reactions against heterologous antigens in mice].
Mice (BALB/c or ICR) were infected with Schistosoma mansoni cercariae. After different intervals (mostly eight weeks) the following antigens were injected: a) sheep erythrocytes--b) DNP-thyroglobulin. Afterwards the immune response against these antigens were checked by means of different methods (plaque assay, haemagglutination test, rosette technique). Immune responses to these antigens were depressed in all cases compared to age matched uninfected mice but it was not possible to transfer this immunosuppression with spleen cells to normal or to irradiated recipients.
Sauer
H
H
Abteilung für Tropenmedizin, Karl-Marx-Universität Leipzig.
Salman
H
H
Ambrosius
H
H
Schäffner
H
H
D000818:Animals; D000917:Antibody Formation; D000921:Antibody-Producing Cells / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology; D004136:Dinitrobenzenes / Q000276:immunology; D004912:Erythrocytes / Q000276:immunology; D007111:Immunity, Cellular; D051379:Mice; D008815:Mice, Inbred Strains / Q000276:immunology; D012555:Schistosomiasis mansoni / Q000276:immunology*; D013154:Spleen / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology
D004136:Dinitrobenzenes
Einfluss einer Schistosoma-mansoni-Infektion auf die Immunreaktion gegen heterologe Antigene in Mäusen.