Simultaneous occurrence of cutaneous T cell lymphoma and low-grade B cell lymphoproliferative diseases. A report of two cases.
Two previously unreported patients with cutaneous T cell lymphoma associated with systemic low-grade B cell proliferations are presented. The first patient had Waldenström's macroglobulinemia and the second had simultaneous chronic lymphocytic leukemia. The use of immunosuppressive drugs or a genetic predisposition may have contributed to the second malignancy. However, the possibility that malignant helper/inducer T lymphocytes were a factor in the promotion of the proliferation of B cells cannot be excluded.
Allué
L
L
Department of Dermatology, Hospital de Bellvitge, Barcelona, Spain.
Domingo
A
A
Moreno
A
A
Crespo
N
N
Marcoval
J
J
Peyrí
J
J
D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications*; D016410:Lymphoma, T-Cell, Cutaneous / Q000150:complications*; D008258:Waldenstrom Macroglobulinemia / Q000150:complications*