Parenteral nutrition hypersensitivity.
Total parenteral nutrition (TPN) is widely used. Although mechanical, septic, and metabolic complications are well known, hypersensitivity skin reactions are rare. We describe a 16-year-old boy with Burkitt's lymphoma who developed a urticarial skin rash when treated with TPN and vitamins. The adverse skin reaction was probably caused by the inactive component of excipient, polysorbate.
Levy
M
M
Department of Paediatrics, Hospital for Sick Children, Toronto, Canada.
Dupuis
L L
LL
D000293:Adolescent; D004342:Drug Hypersensitivity / Q000209:etiology*; D006801:Humans; D008297:Male; D010289:Parenteral Nutrition, Total / Q000009:adverse effects*; D011136:Polysorbates / Q000009:adverse effects; D014581:Urticaria / Q000139:chemically induced
D011136:Polysorbates