title: Submental administration of succinylcholine in children.
abstract: During inhalation induction of the pediatric patient, laryngospasm can develop before intravenous access has been established. The intramuscular administration of succinylcholine is commonly used in such instances. This study was designed to determine if the injection of succinylcholine by an extraoral submental approach would be an acceptable method of terminating laryngospasm when compared to conventional intramuscular sites. Following induction with halothane and nitrous oxide in oxygen, a total of fifteen ASA 1 children were given 3.0 mg/kg intramuscular succinylcholine either intralingually by a submental approach, or using the upper leg musculature in order to electromyographically measure the time to maximum (or 90 percent depression from baseline) twitch depression. The intralingual submental injection had a mean twitch depression of 265 +/- 62.5 seconds compared to the quadriceps femoris at 295 +/- 42.6 seconds. A group with digital massage of the intralingual injection site produced a mean depression time of 133 +/- 11.9 seconds and was also the only group providing 100% success rate in reaching the desired twitch depression level. This may suggest that the operator should consider digital massage to produce a more predictable and desirable result.
authors.affiliation: Medical College of Virginia, Richmond.
authors.forename: R J
authors.initials: RJ
authors.lastname: Redden
authors.forename: M
authors.initials: M
authors.lastname: Miller
authors.forename: R L
authors.initials: RL
authors.lastname: Campbell
mesh_terms: D000286:Administration, Sublingual; D000768:Anesthesia, General / Q000379:methods; D002648:Child; D002675:Child, Preschool; D002680:Chin; D006801:Humans; D007273:Injections, Intramuscular; D007826:Laryngismus / Q000517:prevention & control*; D008405:Massage; D013390:Succinylcholine / Q000008:administration & dosage*
chemical_list: D013390:Succinylcholine