Oxidation of nucleosides and nucleotides by peroxosulfate ions.
Treatment of 5-methylpyrimidine nucleosides and nucleotides with sodium peroxodisulfate in sodium phosphate buffer solution at pH 7.0 at 75 degrees C resulted in the selective oxidation of the methyl group. On the other hand, oxidation of thymidine by potassium peroxomonosulfate gave thymidine glycols.
Itahara
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Institute of Chemistry, College of Liberal Arts, Kagoshima University, Japan.
Koga
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Yoshitake
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D002021:Buffers; D015394:Molecular Structure; D009705:Nucleosides / Q000737:chemistry*; D009711:Nucleotides / Q000737:chemistry*; D010084:Oxidation-Reduction; D012964:Sodium / Q000737:chemistry*; D017670:Sodium Compounds; D013431:Sulfates; D013464:Sulfuric Acids / Q000737:chemistry*
D002021:Buffers; D009705:Nucleosides; D009711:Nucleotides; D017670:Sodium Compounds; D013431:Sulfates; D013464:Sulfuric Acids; D012964:Sodium; C048813:potassium peroxymonosulfuric acid; C024625:sodium persulfate