title: The substrate specificity of glycerol ester hydrolase from pig aorta and serum.
abstract: The activity of glycerol ester hydrolase (GEH) from aorta wall, at optimum pH and triacylglycerol substrate concentration (optimal for each substrate) decreased in the following order: C18:1 greater than or equal to C18:2 greater than or equal to C18:0 greater than or equal to C18:3 greater than or equal to C16:0. At optimum pH and the same substrate concentration (1 mM), the activity of GEH from aorta wall decreased in a slightly different order: C18:1 greater than or equal to C18:2 greater than or equal to C18:3 greater than C18:0 greater than C16:0 and that of the enzyme from serum in the order: C18:1 = C18:3 greater than C18:2 greater than or equal to C16:0 greater than or equal to C18:0. These differences in substrate affinity of GEH may influence the metabolism and accumulation of acylalcohols and alcohols in arterial wall and serum.
authors.affiliation: Department of General Chemistry, Medical Academy, Poznań, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Pioruńska-Stolzmann
mesh_terms: D000818:Animals; D001011:Aorta / Q000201:enzymology*; D005227:Fatty Acids / Q000737:chemistry / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D008049:Lipase / Q000097:blood / Q000378:metabolism*; D013053:Spectrophotometry; D013379:Substrate Specificity; D014280:Triglycerides / Q000378:metabolism*
chemical_list: D005227:Fatty Acids; D014280:Triglycerides; D008049:Lipase