Codon usage and secondary structure of mRNA.
The specific codon usage pattern of the repetitive unit nucleotide sequence of silk fibroin mRNA suggests that selection has operated on the codon usage to optimize the secondary structure characteristic of the mRNA. The correlation between the stability map of local secondary structure of type I collagen mRNA and the codon usage pattern and the translation rate of the collagen is also implied.
Zama
M
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Division of Biology, National Institute of Radiological Sciences, Chiba-shi, Japan.
D000818:Animals; D005075:Biological Evolution; D012831:Bombyx / Q000235:genetics; D003062:Codon; D005349:Fibroins / Q000235:genetics; D009690:Nucleic Acid Conformation; D009691:Nucleic Acid Denaturation; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000737:chemistry / Q000235:genetics*; D012091:Repetitive Sequences, Nucleic Acid
D003062:Codon; D012333:RNA, Messenger; D005349:Fibroins