title: Chlorambucil lung toxicity.
abstract: A 67-year-old man, who had received intermittent courses of oral chlorambucil and prednisone as therapy for chronic lymphocytic leukaemia over a period of 3.5 years, developed fatal lung fibrosis. A case report and brief review of the current data on chlorambucil-induced lung disease are presented.
authors.affiliation: Department of Haematology, University College Hospital, London, UK.
authors.forename: F J
authors.initials: FJ
authors.lastname: Giles
authors.forename: M P
authors.initials: MP
authors.lastname: Smith
authors.forename: A H
authors.initials: AH
authors.lastname: Goldstone
mesh_terms: D000368:Aged; D002699:Chlorambucil / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy; D008297:Male; D011658:Pulmonary Fibrosis / Q000139:chemically induced*
chemical_list: D002699:Chlorambucil