Spiral gradient endpoint: a new method of susceptibility testing.
The key to SGE is an instrument that deposits the antimicrobial agent in predetermined, decreasing concentrations in a spiral pattern on an agar plate. The bacterial inoculum is streaked radially from the center of the plate across the spiral. The drug concentration at the point in the spiral where bacterial growth ends is its MIC.
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Department of Obstetrics and Gynecology, Duke University School of Medicine, Durham, N.C.
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects / Q000254:growth & development*; D008826:Microbial Sensitivity Tests / Q000295:instrumentation / Q000379:methods*
D000900:Anti-Bacterial Agents