Anticardiolipin antibodies in HIV-negative and HIV-positive haemophiliacs.
Anticardiolipin antibodies (ACA) were determined in 72 heavily transfused haemophiliacs, 43 HIV-positive and 29 HIV-negative. The presence of ACA was detected in 10 patients, all of them infected by HIV: 8 in CDC II, 1 in CDC III and 1 in CDC IV. The comparison with alterations of other laboratory markers in HIV-infected patients did not show any statistically significant difference between ACA-negative and -positive patients. In summary, ACA were found only in HIV-infected haemophiliacs. In this subgroup of patients the presence of ACA was not associated with progression to AIDS.
Naimi
N
N
Department of Medicine, University Hospital, Geneva, Switzerland.
Plancherel
C
C
Bosser
C
C
Jeannet
M
M
de Moerloose
P
P
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology; D000906:Antibodies / Q000097:blood*; D001803:Blood Transfusion; D002308:Cardiolipins / Q000276:immunology*; D015658:HIV Infections / Q000276:immunology; D006679:HIV Seropositivity / Q000276:immunology*; D006467:Hemophilia A / Q000276:immunology* / Q000628:therapy; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis
D000906:Antibodies; D002308:Cardiolipins; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M