Why lose an in vitro fertilization cycle when stimulation fails?
Different protocols using agonists of GnRH-a have been proposed for the ovarian stimulation in IVF cycles. In case of stimulation failure with the flare-up protocol, we have investigated whether an immediate switch to pituitary blockade by the long-acting analog may avoid the cycle to be canceled. This procedure allows a rescue of cycles among poor responders and does not have any deleterious effect on the recruitment of follicles, oocyte quality, fertilization, and pregnancy rates.
Germond
M
M
Département de Gynécologie-Obstétrique, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Senn
A
A
Reymond
O
O
de Grandi
P
P
D000328:Adult; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy; D008596:Menotropins / Q000009:adverse effects / Q000627:therapeutic use; D010048:Ovarian Cysts / Q000139:chemically induced; D010053:Ovary / Q000503:physiopathology*; D011247:Pregnancy; D013268:Stimulation, Chemical
D008596:Menotropins