title: Hereditary ataxias: epidemiological aspects.
abstract: Hereditary ataxias, hereditary spastic paraplegia and Charcot-Marie-Tooth syndrome (HA) are chronic progressive neurological diseases. Epidemiologic studies of these disorders are few. In a geographically well-defined Danish population, we present incidence rates, cumulated incidence rates and prevalence for patients with HA based on modern continuous-time survival analysis techniques. From these, prevalence has been estimated to be 6.06 per 10(5) in the 10 to 50-year-old population. Combined risk of HA was found to be 0.16% for women and 0.20% for men up to their 51st birthday.
authors.affiliation: Neuromedical Department, Rigshospitalet, Denmark.
authors.forename: L
authors.initials: L
authors.lastname: Werdelin
authors.forename: N
authors.initials: N
authors.lastname: Keiding
mesh_terms: D000293:Adolescent; D000328:Adult; D002524:Cerebellar Ataxia / Q000401:mortality; D002607:Charcot-Marie-Tooth Disease / Q000401:mortality; D002648:Child; D003430:Cross-Sectional Studies; D003718:Denmark / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D005621:Friedreich Ataxia / Q000401:mortality; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015419:Spastic Paraplegia, Hereditary / Q000401:mortality; D013132:Spinocerebellar Degenerations / Q000401:mortality*; D015996:Survival Rate