title: Effect of a potent analog of human growth hormone-releasing factor on carcass composition and quality of crossbred market pigs.
abstract: The effect of a human growth hormone-releasing factor (hGRF) analog ([desamino-Tyr1, D-Ala2, Ala15] hGRF(1-29)NH2) on the carcass composition of crossbred barrows was evaluated. pH, color and collagen content were measured on 74 animals distributed among the following five treatments started at about 50 kg BW: T1, control saline three times daily (TID); T2, hGRF analog (1.66 micrograms/kg, TID); T3, hGRF analog (3.33 micrograms/kg, TID); T4, hGRF analog (6.66 micrograms/kg, TID) and T5, hGRF analog (10 micrograms/kg, once daily). Animals were slaughtered at approximately 106 kg BW giving an average of 55 d on test. Carcass composition was determined on eight animals from T1 and eight animals from T4. The left side of each carcass was divided into four untrimmed commercial cuts: ham, loin, shoulder and belly, which then were dissected into muscle, separable fat, bone and skin. Ham, loin and belly weights were not affected by GRF treatment, but shoulder weight was increased (P less than .05; 10.11 vs 11.15 kg, SE = .21). There was an increase (P less than .0.05) in muscle content of all the cuts considered and a concomitant decrease (P less than .05) in fat content. The analog increased muscle weight by 16% and decreased fat weight by 25% in the pooled tissues of the shoulder, ham and loin. Overall, hGRF analog increased skin and bone weights by 39% and 19%, respectively. Chemical analysis demonstrated that the hGRF analog increased overall protein accretion in the carcass by 10.5% and decreased crude fat by 28.7%.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Agriculture Canada, Lennoxville Research Station, Quebec.
authors.forename: S A
authors.initials: SA
authors.lastname: Pommier
authors.forename: P
authors.initials: P
authors.lastname: Dubreuil
authors.forename: G
authors.initials: G
authors.lastname: Pelletier
authors.forename: P
authors.initials: P
authors.lastname: Gaudreau
authors.forename: T F
authors.initials: TF
authors.lastname: Mowles
authors.forename: P
authors.initials: P
authors.lastname: Brazeau
mesh_terms: D000273:Adipose Tissue / Q000187:drug effects; D000818:Animals; D001823:Body Composition / Q000187:drug effects*; D001835:Body Weight / Q000187:drug effects; D013007:Growth Hormone-Releasing Hormone / Q000031:analogs & derivatives / Q000494:pharmacology*; D008297:Male; D008460:Meat / Q000032:analysis / Q000592:standards*; D009132:Muscles / Q000187:drug effects; D009929:Organ Size / Q000187:drug effects; D013552:Swine / Q000254:growth & development*
chemical_list: D013007:Growth Hormone-Releasing Hormone