title: Alterations in intrauterine oxygen tension during the estrous cycle in the rat and hamster and its regulation by ovarian steroid hormones: a comparative study.
abstract: The results indicate that marked fluctuations in oxygen availability occur during the estrous cycle in both rats and hamsters. Patterns of luminal pO2 were similar in that levels were intermediate during metestrus and maximal during diestrus. By contrast, minimal pO2 levels occurred during estrus in the rat vs. during proestrus in the hamster. The species also differed in the range of mean pO2 occurring during the cycle: approximately 5-50 mmHg in the hamster vs. 25-50 mmHg in the rat. Ovariectomy results in marked increases in luminal pO2 in both species. The increase is reduced by hormone replacement.
authors.affiliation: Department of Anatomy/Cell Biology, Wayne State University School of Medicine, Detroit, Michigan.
authors.forename: D L
authors.initials: DL
authors.lastname: Kaufman
authors.forename: J A
authors.initials: JA
authors.lastname: Mitchell
mesh_terms: D000818:Animals; D006224:Cricetinae; D004970:Estrone / Q000494:pharmacology; D004971:Estrus / Q000378:metabolism*; D005260:Female; D008647:Mesocricetus; D010052:Ovariectomy; D010100:Oxygen / Q000097:blood / Q000378:metabolism*; D011374:Progesterone / Q000494:pharmacology; D051381:Rats; D013045:Species Specificity; D014599:Uterus / Q000187:drug effects / Q000378:metabolism*
chemical_list: D004970:Estrone; D011374:Progesterone; D010100:Oxygen