title: [Tubercular Addison's disease with high titers of microsomal thyroid antibodies and reduced thyroid function reserve].
abstract: This case reports deals with a male patient, white, aged 51, bricklayer, tobacco smoker. At 43 years old a tubercular epididimite was surgically treated with orchiectomy. Recently, the reports marked weakness, weight loss, headache, vertigo, hypotension. On admittance to the hospital, hyperpigmentation was also present. Previous therapy (cortisone acetate 40 mg/die), was suspended, clinical investigations showed impaired adrenal and thyroidal functions; antimicrosomal antibodies were also present. Therefore therapy with cortisone acetate (25 mg x 2/die, 9-alpha-fluorohydrocortisone 0.1 mg/die and L-thyroxine 100 mcg/die) was instituted with marked improvement of the patient's conditions. This case reports highlights the importance of proceeding with complete investigations on the system, even when dealing with a tubercular Addison's disease.
authors.affiliation: Cattedra di I Patologia Medica e Metodologia Clinica, Università degli Studi La Sapienza di Roma.
authors.forename: C
authors.initials: C
authors.lastname: Letizia
authors.forename: M
authors.initials: M
authors.lastname: Sellini
authors.forename: S
authors.initials: S
authors.lastname: Baccarini
authors.forename: D
authors.initials: D
authors.lastname: Diacinti
authors.forename: D
authors.initials: D
authors.lastname: Scavo
mesh_terms: D000224:Addison Disease / Q000097:blood / Q000150:complications / Q000276:immunology*; D000906:Antibodies / Q000097:blood; D006801:Humans; D008297:Male; D008861:Microsomes / Q000276:immunology; D008875:Middle Aged; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000276:immunology / Q000503:physiopathology*; D014376:Tuberculosis / Q000097:blood / Q000150:complications / Q000276:immunology*
chemical_list: D000906:Antibodies
vernacular_title: Morbo di Addison tubercolare con elevato titolo di anticorpi antimicrosomiali tiroidei e ridotta riserva funzionale della tiroide.