[In vitro sensitivity to 5-fluorocytosine and amphotericin B of yeasts of the Candida genus isolated in Barcelona].
In 200 strains of Candida sp, 38.5% were found to have intermediate sensitivity or to be resistant to amphotericin B and/or 5-fluorocytosine by the agar diffusion method. When the minimal inhibitory concentrations of these strains were measured, only 7.8% were resistant to amphotericin B and 2.8% to 5-fluorocytosine. The species with the highest levels of resistance were C. parapsilosis, C. tropicalis and Torulopsis glabrata. Candida albicans did not show resistance to 5-fluorocytosine.
Torres-Rodríguez
J M
JM
Servei de Microbiologia Clínica, Hospital del Mar, Barcelona.
Sabaté
M
M
Gallach
C
C
Carrillo
A
A
Madrenys
N
N
D000666:Amphotericin B / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects*; D004352:Drug Resistance, Microbial; D005437:Flucytosine / Q000494:pharmacology*; D006761:Hospitals; D006801:Humans; D008826:Microbial Sensitivity Tests; D013030:Spain
D000666:Amphotericin B; D005437:Flucytosine
Sensibilidad in vitro a la 5-fluorocitosina y anfotericina B de levaduras del género Candida aisladas en Barcelona.