Surface anesthetic effect and topical tolerance of one dose 0.25% bupranolol in eye-healthy people.
In a randomised, prospective, parallel, double-masked study we examine the surface anesthetic effect of Bupranolol 0.25% in an oily solution. Bupranolol 0.25% decreases the corneal sensitivity to 23 mg/S, with the maximum between the 6th and 15th minute after application.
Bastian
B
B
Department of Ophthalmology, University of Saarland, Homburg, FRG.
Höh
H
H
Ruprecht
K W
KW
D000287:Administration, Topical; D000328:Adult; D000772:Anesthesia, Local; D002046:Bupranolol / Q000494:pharmacology*; D003315:Cornea / Q000187:drug effects* / Q000503:physiopathology; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000503:physiopathology; D011446:Prospective Studies; D012684:Sensory Thresholds / Q000187:drug effects
D002046:Bupranolol