title: [Plasma separation in acute, intravenous phenytoin poisoning].
abstract: A two year old boy suffered an acute phenytoin intoxication following intravenous treatment of seizures. After two days in coma detoxification with plasma separation was started. The course of clinical symptoms and phenytoin elimination is described and the efficacy of the method in treating phenytoin intoxication is discussed.
authors.affiliation: Klinik mit Poliklinik für Kinder und Jugendliche, Universität Erlangen-Nürnberg.
authors.forename: J
authors.initials: J
authors.lastname: Scharf
authors.forename: H
authors.initials: H
authors.lastname: Ruder
authors.forename: D
authors.initials: D
authors.lastname: Harms
mesh_terms: D004305:Dose-Response Relationship, Drug; D062787:Drug Overdose / Q000628:therapy*; D004569:Electroencephalography / Q000187:drug effects; D004830:Epilepsy, Tonic-Clonic / Q000188:drug therapy*; D006801:Humans; D007223:Infant; D007262:Infusions, Intravenous; D008297:Male; D008508:Medication Errors; D010672:Phenytoin / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000506:poisoning*; D010956:Plasmapheresis
chemical_list: D010672:Phenytoin
vernacular_title: Plasmaseparation bei akuter, intravenöser Phenytoinintoxikation.