title: [Pituitary-testicular evaluation in patients with chronic renal insufficiency in hemodialysis treatment].
abstract: Hormone assays were performed in 10 nephropathic men on haemodialysis who revealed reduced libido and importance. In particular, testosterone, 17-beta-estradiol, prolactin, FSH and LH plasma levels were assayed in 8 patients before dialysis and at last, after both long and short interdialytic periods. Below normal testosterone, elevated 17-beta-estradiol, FSH at the upper limits of the range and markedly increased LH levels were noticed; prolactin levels were almost normal. No substantial difference was observed between pre- and post-dialytic hormone levels, after either interdialytic periods. Testosterone, 17 beta-estradiol, prolactin, FSH and LH plasma levels were again assayed in 8 patients (six of the former group + two more) and afterwards a test with HCG was performed. Basal hormone levels agreed with the previous ones; prolactin levels were quite normal. An almost complete absence of response of testosterone and 17-beta-estradiol to HCG was noticed. These results demonstrate a primary hypogonadism responsible for reduced libido and impotence in the patients on haemodialysis investigated.
authors.affiliation: Divisione di Medicina Generale, Regione Campania, U.S.L. n. 35, Ospedale S. Leonardo, Castellammare di Stabia.
authors.forename: A
authors.initials: A
authors.lastname: Coppola
authors.forename: G
authors.initials: G
authors.lastname: Cuomo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D006063:Chorionic Gonadotropin / Q000097:blood; D007172:Erectile Dysfunction / Q000097:blood* / Q000503:physiopathology; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood* / Q000503:physiopathology / Q000628:therapy; D007989:Libido; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis
chemical_list: D006063:Chorionic Gonadotropin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
vernacular_title: Valutazione ipofisi-testicolare in pazienti con insufficienza renale cronica in trattamento emodialitico.