title: [Association of sarcoidosis and primary biliary cirrhosis: review of the literature apropos of a new case].
abstract: We report a case of sarcoidosis associated with primary biliary cirrhosis in a 56-year old woman, with a 5 years' follow up. Sarcoidosis was ascertained by chest X ray, gallium scintigraphy, broncho-alveolar washing and liver biopsy (intralobular epithelioid granulomas). The diagnosis of primary biliary cirrhosis was based on IgM level increase (4 g/l), AMA positivity (1/1000) and liver biopsy assessment (non suppurative chronic cholangitis). Such an association is rare (12 detailed cases in literature), brings out pathophysiological questions and points to an additional mechanism of cholestasis in patients with sarcoidosis.
authors.affiliation: Clinique de Médicine Interne et des Maladies du Fole, CHU Pontchaillou, Rennes.
authors.forename: H
authors.initials: H
authors.lastname: Jouanolle
authors.forename: B
authors.initials: B
authors.lastname: Turlin
authors.forename: D
authors.initials: D
authors.lastname: Guyader
authors.forename: Y
authors.initials: Y
authors.lastname: Deugnier
authors.forename: P
authors.initials: P
authors.lastname: Brissot
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000209:etiology*; D008171:Lung Diseases / Q000150:complications*; D008875:Middle Aged; D012507:Sarcoidosis / Q000150:complications*
vernacular_title: Association sarcoïdose et cirrhose biliaire primitive: revue de la littérature à propose d'un nouveau cas.