Leg duplication and kidney agenesis: case report and pathogenic considerations.
A case is given of a male born with a total duplication of the left leg. In addition, ipsilateral kidney agenesis was found. Three possible mechanisms of leg duplication are given. The association with renal agenesis is discussed in terms of a polytopic developmental field defect.
Van Groesen
P J
PJ
Clinical Genetics Center Utrecht, The Netherlands.
Beemer
F A
FA
Van de Kamp
J H
JH
D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging / Q000235:genetics*; D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003025:Clubfoot / Q000000981:diagnostic imaging / Q000235:genetics*; D005500:Follow-Up Studies; D005817:Genetic Counseling; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007668:Kidney / Q000002:abnormalities*; D007866:Leg / Q000002:abnormalities* / Q000000981:diagnostic imaging; D007870:Leg Length Inequality / Q000000981:diagnostic imaging / Q000235:genetics; D008297:Male; D011859:Radiography