title: A case of Rh isoimmunization: should threatened first-trimester abortion be an indication for Rh immune globulin prophylaxis?
abstract: Despite the recommended 28 weeks' gestation antenatal, postnatal, and postabortion prophylaxis with Rh immune globulin, residual Rh immunization still occurs in Rh-negative women. We describe a patient whose history suggests development of an anti-D antibody after first-trimester bleeding. To our knowledge, this is the first such case reported in the English literature.
authors.affiliation: Department of Laboratory Medicine and Pathology, Hennepin County Medical Center, Minneapolis, MN 55403.
authors.forename: V D
authors.initials: VD
authors.lastname: Dayton
authors.forename: D S
authors.initials: DS
authors.lastname: Anderson
authors.forename: J T
authors.initials: JT
authors.lastname: Crosson
authors.forename: S H
authors.initials: SH
authors.lastname: Cruikshank
mesh_terms: D000033:Abortion, Threatened / Q000150:complications* / Q000628:therapy; D000328:Adult; D005260:Female; D006801:Humans; D007116:Immunization, Passive; D007518:Isoantibodies / Q000032:analysis; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D012203:Rh Isoimmunization / Q000150:complications* / Q000628:therapy; D014592:Uterine Hemorrhage / Q000150:complications
chemical_list: D007518:Isoantibodies