[The effect of sterol metabolism in a model ecological system Drosophila-yeasts on the crossing-over in Drosophila].
The absence of sterols available for metabolism causes the death of Drosophila larva. Addition of suboptimal cholesterol doses to this medium allows the portion of larvae to survive. Sterol-deficient diet at the preimaginal stages leads to suppression of both spontaneous and high-temperature induced crossingover in Drosophila females. Two possible explanations for dependence of recombination process on sterol metabolism are suggested: 1) the shortage of precursor for ecdisons biosynthesis was the cause of discordance of meiotic events; 2) suppression of crossingover occurs, due to alteration of cell membrans' structure.
Kamilova
T A
TA
Luchnikova
E M
EM
Inge-Vechtomov
S G
SG
D000818:Animals; D003434:Crossing Over, Genetic; D003470:Culture Media; D004331:Drosophila melanogaster / Q000235:genetics* / Q000502:physiology; D004463:Ecology; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000378:metabolism*; D013261:Sterols / Q000378:metabolism*
D003470:Culture Media; D013261:Sterols
Vliianie sterinovogo metabolizma v model'noĭ ékologicheskoĭ sisteme drozofila-drozhzhi na krossingover u drozofily.