Comparison of vancomycin-inducible proteins from four strains of Enterococci.
Vancomycin-inducible proteins of 39.5 and 39 kDa from respectively, low-level and high-level resistant Enterococci were compared. Electrophoretic, immunoblot and peptide analysis revealed three types of protein, one in a low-level resistant strain of E. faecium, one in 2 high-level-resistant strains of E. faecium, and one in a high-level resistant strain of E. faecalis. The inducible proteins of E. faecium and E. faecalis, of 39.5 and 39 kDa respectively, which may function in a similar fashion (Al-Obeid et al. (1990) Antimicrob. Agents Chemother. 34, 252-256), are not related immunologically.
al-Obeid
S
S
Laboratoire de Microbiologie Médicale, Université Paris VI, France.
Gutmann
L
L
Shlaes
D M
DM
Williamson
R
R
Collatz
E
E
D001426:Bacterial Proteins / Q000096:biosynthesis*; D004352:Drug Resistance, Microbial; D015180:Electrophoresis, Gel, Two-Dimensional; D004591:Electrophoresis, Polyacrylamide Gel; D013293:Enterococcus faecalis / Q000187:drug effects / Q000378:metabolism; D015151:Immunoblotting; D013291:Streptococcus / Q000187:drug effects / Q000378:metabolism*; D014640:Vancomycin / Q000494:pharmacology*
D001426:Bacterial Proteins; D014640:Vancomycin