Efficacy of mitomycin C against alveolar Echinococcus.
Mitomycin C was tested against the metacestode stage of Echinococcus multilocularis in jirds. The efficacy of 61-76% was achieved within 1 month of treatment with a total dose of 0.04, 0.08 or 0.3 mg.
Novak
M
M
Department of Biology, University of Winnipeg, Manitoba, Canada.
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004443:Echinococcosis / Q000188:drug therapy*; D004446:Echinococcus / Q000187:drug effects; D005849:Gerbillinae; D008297:Male; D016685:Mitomycin; D008937:Mitomycins / Q000494:pharmacology / Q000627:therapeutic use*
D008937:Mitomycins; D016685:Mitomycin