Chlorambucil lung toxicity.
A 67-year-old man, who had received intermittent courses of oral chlorambucil and prednisone as therapy for chronic lymphocytic leukaemia over a period of 3.5 years, developed fatal lung fibrosis. A case report and brief review of the current data on chlorambucil-induced lung disease are presented.
Giles
F J
FJ
Department of Haematology, University College Hospital, London, UK.
Smith
M P
MP
Goldstone
A H
AH
D000368:Aged; D002699:Chlorambucil / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy; D008297:Male; D011658:Pulmonary Fibrosis / Q000139:chemically induced*
D002699:Chlorambucil