[Clearance effect of 3H-cholesterol by Apo-AI/DPPC liposome from cultured SMC of rabbits and tree shrew].
Micellar liposomes were prepared by using Apo-AI from rabbit or tree shrew and dipalmitoylphosphatidyl choline (DPPC), with or without cholesterol through a rapid dialysis method. An obvious ability was noticed in clearing of 3H-cholesterol from the cultured smooth muscle cells (SMC) and a cross effect of Apo-AI originated from either rabbit's or tree shrew's serum on the clearance rate of 3H-cholesterol from the cultured SMC of these two species of animals was also obtained.
Cai
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Department of Pathology, Faculty of Basic Medicine, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing.
D015060:1,2-Dipalmitoylphosphatidylcholine / Q000494:pharmacology*; D000818:Animals; D001011:Aorta; D016632:Apolipoprotein A-I; D001054:Apolipoproteins A / Q000494:pharmacology*; D002478:Cells, Cultured; D002784:Cholesterol / Q000378:metabolism*; D008075:Lipoproteins, HDL / Q000494:pharmacology*; D008081:Liposomes; D008657:Metabolic Clearance Rate / Q000187:drug effects; D009131:Muscle, Smooth, Vascular / Q000166:cytology*; D011817:Rabbits; D014418:Tupaiidae
D016632:Apolipoprotein A-I; D001054:Apolipoproteins A; D008075:Lipoproteins, HDL; D008081:Liposomes; D015060:1,2-Dipalmitoylphosphatidylcholine; D002784:Cholesterol