An unusual case of Candida tropicalis sepsis in a patient submitted to allogeneic bone marrow transplantation.
We describe an exceptional case of Candida tropicalis sepsis in a patient submitted to allogeneic BMT; the diagnosis was made on a peripheral blood smear, when the pt was neutropenic and only mildly febrile. The combination of GM-CSF to accelerate hematological recovery and the possibility of administering large doses of a liposomal form of Amphotericin B were the contributing factors to the resolution of the infection.
Rosti
G
G
Istituto di Ematologia L. e A. Seràgnoli, Ospedale S. Orsola, Bologna, Italy.
Bandini
G
G
Miggiano
M C
MC
Albertazzi
L
L
Ricci
P
P
Verlicchi
F
F
Pileri
S
S
Tura
S
S
D000328:Adult; D000380:Agranulocytosis / Q000209:etiology; D000666:Amphotericin B / Q000008:administration & dosage / Q000627:therapeutic use; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002177:Candidiasis / Q000188:drug therapy / Q000209:etiology*; D002405:Catheterization, Central Venous / Q000009:adverse effects; D003131:Combined Modality Therapy; D004337:Drug Carriers; D006086:Graft vs Host Disease / Q000150:complications; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D007166:Immunosuppressive Agents / Q000009:adverse effects; D007370:Interferon Type I / Q000627:therapeutic use; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000601:surgery* / Q000628:therapy; D008081:Liposomes; D008297:Male; D010032:Otitis Externa / Q000209:etiology; D011552:Pseudomonas Infections / Q000209:etiology; D011994:Recombinant Proteins; D018805:Sepsis / Q000188:drug therapy / Q000209:etiology*
D004337:Drug Carriers; D007155:Immunologic Factors; D007166:Immunosuppressive Agents; D007370:Interferon Type I; D008081:Liposomes; D011994:Recombinant Proteins; D000666:Amphotericin B