title: Facilitated transport of oxygen through hemoglobin solutions.
abstract: A method for quantitative analysis of hemoglobin color to estimate the oxygen saturation was developed. The method uses an image-input and -processing system composed of a 3-tube video camera and a digital image analyzer. When the system is connected to a microscope, the facilitated diffusion of oxygen in hemoglobin solutions can be observed and analyzed in a position-sensitive manner. The results led to a new transport model expressed as: J = k'CY/d, where J is the oxygen flux, C is the hemoglobin concentration, Y is the oxygen saturation of hemoglobin, d is the distance between the entrance of oxygen and the diffusion front, and k' is a constant.
authors.affiliation: Department of Physico-chemical Physiology, Osaka University Medical School, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Hashimoto
authors.forename: R
authors.initials: R
authors.lastname: Hata
authors.forename: T
authors.initials: T
authors.lastname: Shiga
authors.forename: A
authors.initials: A
authors.lastname: Isomoto
authors.forename: M
authors.initials: M
authors.lastname: Uozumi
mesh_terms: D000465:Algorithms; D001693:Biological Transport, Active; D004058:Diffusion; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D008954:Models, Biological; D010100:Oxygen / Q000378:metabolism*; D012996:Solutions
chemical_list: D006454:Hemoglobins; D012996:Solutions; D010100:Oxygen