title: [A case of B-cell non-Hodgkin's lymphoma with prominent splenomegaly and high serum titer of cold agglutinin].
abstract: The case of 37-year-old male with non-Hodgkin's lymphoma with prominent splenomegaly is presented. The spleen that was removed for analysis had a weight of 2690 grams and a section inspection revealed multiple, whitish, small nodules that were disseminated throughout the entire spleen. It was microscopically demonstrated to be a B-Cell lymphoma of diffuse, medium-sized cells and an IgM.kappa Type. This case also was complicated by a high serum titer of cold agglutinin that was decreased by chemotherapy.
authors.affiliation: 1st Dept. of Int. Med., Jikei Univ. School of Med.
authors.forename: K
authors.initials: K
authors.lastname: Fujise
authors.forename: M
authors.initials: M
authors.lastname: Yazawa
authors.forename: N
authors.initials: N
authors.lastname: Hashimoto
authors.forename: H
authors.initials: H
authors.lastname: Sujino
authors.forename: T
authors.initials: T
authors.lastname: Yanagisawa
authors.forename: H
authors.initials: H
authors.lastname: Kawase
authors.forename: F
authors.initials: F
authors.lastname: Ishihara
authors.forename: H
authors.initials: H
authors.lastname: Kameda
authors.forename: S
authors.initials: S
authors.lastname: Kuraishi
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
mesh_terms: D000328:Adult; D000373:Agglutinins / Q000378:metabolism*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001402:B-Lymphocytes; D003131:Combined Modality Therapy; D003450:Cryoglobulins; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D007075:Immunoglobulin M / Q000378:metabolism; D007145:Immunoglobulin kappa-Chains / Q000378:metabolism; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000276:immunology* / Q000628:therapy; D008297:Male; D011241:Prednisone / Q000008:administration & dosage; D013156:Splenectomy; D013163:Splenomegaly / Q000209:etiology*; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D000373:Agglutinins; D003450:Cryoglobulins; D007075:Immunoglobulin M; D007145:Immunoglobulin kappa-Chains; C029443:cold agglutinins; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone