title: [Craniocervical amyloid tumor with destructive spondyloarthropathy and myelocompression as a rare complication of long-term dialysis].
abstract: Dialysis-associated amyloidosis has become a frequent and sometimes disabling complication in long-term dialysis patients. The main protein implicated in amyloidosis is beta 2 microglobulin, which accumulates in patients with renal insufficiency. We report on a 47-year-old patient, who was on haemodialysis treatment for 17 years. After a period of 15 years on dialysis treatment he underwent surgery for a carpal tunnel syndrome. Two years later he developed destructive spondyloarthropathy of the cervical region and destruction of the occipital bone. He lost stability of his neck necessitating his remaining mainly in the lying position. Since the type of dialysis membrane may play an important role in the pathogenesis of dialysis-associated amyloidosis, a dialysator with a polysulfone membrane, which is assume to have a beneficial effect on the progression of amyloidosis, was established.
authors.affiliation: I. Medizinische Abteilung, Landeskrankenhauses Klagenfurt.
authors.forename: M
authors.initials: M
authors.lastname: Ausserwinkler
authors.forename: O
authors.initials: O
authors.lastname: Karlo
authors.forename: F
authors.initials: F
authors.lastname: Ebner
authors.forename: P
authors.initials: P
authors.lastname: Schmidt
mesh_terms: D000686:Amyloidosis / Q000209:etiology*; D001368:Axis, Cervical Vertebra / Q000473:pathology; D002349:Carpal Tunnel Syndrome / Q000209:etiology; D002482:Cellulose / Q000009:adverse effects / Q000031:analogs & derivatives; D001270:Cervical Atlas / Q000473:pathology; D002574:Cervical Vertebrae / Q000473:pathology; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D007688:Kidneys, Artificial / Q000009:adverse effects*; D008134:Long-Term Care; D008279:Magnetic Resonance Imaging; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D009777:Occipital Bone / Q000473:pathology; D009809:Odontoid Process / Q000473:pathology; D013117:Spinal Cord Compression / Q000209:etiology*; D013167:Spondylitis, Ankylosing / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D001613:beta 2-Microglobulin / Q000378:metabolism
chemical_list: D008567:Membranes, Artificial; D001613:beta 2-Microglobulin; D002482:Cellulose; C009865:cuprammonium cellulose
vernacular_title: Kraniozervikaler Amyloidtumor mit destruktiver Spondylarthropathie und Myelokompression als seltene Langzeitdialysekomplikation.