title: [The effect of sterol metabolism in a model ecological system Drosophila-yeasts on the crossing-over in Drosophila].
abstract: The absence of sterols available for metabolism causes the death of Drosophila larva. Addition of suboptimal cholesterol doses to this medium allows the portion of larvae to survive. Sterol-deficient diet at the preimaginal stages leads to suppression of both spontaneous and high-temperature induced crossingover in Drosophila females. Two possible explanations for dependence of recombination process on sterol metabolism are suggested: 1) the shortage of precursor for ecdisons biosynthesis was the cause of discordance of meiotic events; 2) suppression of crossingover occurs, due to alteration of cell membrans' structure.
authors.forename: T A
authors.initials: TA
authors.lastname: Kamilova
authors.forename: E M
authors.initials: EM
authors.lastname: Luchnikova
authors.forename: S G
authors.initials: SG
authors.lastname: Inge-Vechtomov
mesh_terms: D000818:Animals; D003434:Crossing Over, Genetic; D003470:Culture Media; D004331:Drosophila melanogaster / Q000235:genetics* / Q000502:physiology; D004463:Ecology; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000378:metabolism*; D013261:Sterols / Q000378:metabolism*
chemical_list: D003470:Culture Media; D013261:Sterols
vernacular_title: Vliianie sterinovogo metabolizma v model'noĭ ékologicheskoĭ sisteme drozofila-drozhzhi na krossingover u drozofily.