Comparative trial of succinylcholine vs low dose atracurium-lidocaine combination for intubation in short outpatient procedures.
Despite its many disadvantages, succinylcholine is the most commonly used drug for intubation of patients for short out-patient procedure. This double blind trial compared a low dose atracurium/lidocaine combination to succinylcholine for intubation in 40 ASA1 adult patients. Low dose atracurium/lidocaine provided clinical intubating conditions at two minutes and cardiovascular stability equivalent to succinylcholine with significantly less myalgia. Spontaneous respiration was slower after low dose atracurium/lidocaine relative to succinylcholine. Low dose atracurium/lidocaine may provide an acceptable alternative to succinylcholine for intubation in short outpatient procedures.
Luyk
N H
NH
College of Dentistry, Ohio State University, Columbus.
Weaver
J M
JM
Quinn
C
C
Wilson
S
S
Beck
F M
FM
D000328:Adult; D000556:Ambulatory Surgical Procedures; D000766:Anesthesia, Dental; D000768:Anesthesia, General; D001279:Atracurium / Q000008:administration & dosage*; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal / Q000379:methods*; D008012:Lidocaine / Q000008:administration & dosage*; D008297:Male; D008964:Molar, Third / Q000601:surgery*; D013390:Succinylcholine / Q000008:administration & dosage*
D004338:Drug Combinations; D001279:Atracurium; D008012:Lidocaine; D013390:Succinylcholine