[The results of the intraportal allotransplantation of pancreatic islet cell cultures in patients with insulin-dependent diabetes mellitus].
The paper is concerned with the results of the treatment of 11 patients with insulin-dependent diabetes mellitus with surgical pathology by a method of intraportal allotransplantation of pancreatic islet cell (PIC) cultures and with similar surgical pathology without PIC transplantation. Carbohydrate metabolism and the level of plasma hormones were investigated. It has been shown that intraportal administration of PIC suspension into the liver can result in an earlier and more considerable decrease in a dose of exogenous insulin that is very important in the postoperative period. This method permitted double reduction of diabetic patients' stay in hospital.
Boĭko
N I
NI
Pavlovskiĭ
M P
MP
D000005:Abdomen / Q000601:surgery; D000328:Adult; D002478:Cells, Cultured; D002908:Chronic Disease; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000601:surgery*; D005260:Female; D005333:Fetus; D006801:Humans; D016381:Islets of Langerhans Transplantation; D008297:Male; D008875:Middle Aged; D011168:Portal System; D011184:Postoperative Period; D013514:Surgical Procedures, Operative
Rezul'taty intraportal'noĭ allotransplantatsii kul'tur ostrovskikh kletok podzheludochnykh zhelez bol'nym insulinzavisimym sakharnym diabetom.