title: Advantages of a new anticoagulant in routine hematology on the Coulter Counter S-Plus STKR analyzer.
abstract: The authors report the advantages of a new anticoagulant-antiaggregant mixture that avoids the deleterious effects of ethylenediaminotetraacetic acid (EDTA) on mean platelet volume and also prevents EDTA-induced platelet clumping. It is suitable for routine cell counting and sizing with the Coulter Counter S-Plus STKR. The values of the common hematologic parameters agree well with those from EDTA-treated samples and are stable for at least eight hours after sampling.
authors.affiliation: Laboratorio di Chimica Clinica ed Ematologia, Ospedale Maggiore, Verona, Italy.
authors.forename: U
authors.initials: U
authors.lastname: Lippi
authors.forename: M
authors.initials: M
authors.lastname: Schinella
authors.forename: N
authors.initials: N
authors.lastname: Modena
authors.forename: M
authors.initials: M
authors.lastname: Nicoli
authors.forename: G
authors.initials: G
authors.lastname: Lippi
mesh_terms: D000925:Anticoagulants / Q000494:pharmacology*; D001772:Blood Cell Count / Q000295:instrumentation*; D001792:Blood Platelets / Q000187:drug effects; D002951:Citrates / Q000494:pharmacology*; D004338:Drug Combinations / Q000494:pharmacology; D004492:Edetic Acid / Q000494:pharmacology; D006801:Humans; D010974:Platelet Aggregation / Q000187:drug effects; D010976:Platelet Count / Q000295:instrumentation; D011732:Pyridoxal Phosphate / Q000494:pharmacology*; D012016:Reference Values; D014325:Tromethamine / Q000494:pharmacology*
chemical_list: D000925:Anticoagulants; D002951:Citrates; D004338:Drug Combinations; C064185:pyridoxal phosphate, trisodium citrate, tromethamine drug combination; D014325:Tromethamine; D011732:Pyridoxal Phosphate; D004492:Edetic Acid