title: Deletion of a tripeptide sequence from the growth-factor domain of tissue-type plasminogen activator prolongs in vivo circulation.
authors.affiliation: Department of Biotechnology, Smith Kline Beecham, Epsom, Surrey, United Kingdom.
authors.forename: M J
authors.initials: MJ
authors.lastname: Browne
authors.forename: C G
authors.initials: CG
authors.lastname: Chapman
authors.forename: I
authors.initials: I
authors.lastname: Dodd
authors.forename: A F
authors.initials: AF
authors.lastname: Esmail
authors.forename: J H
authors.initials: JH
authors.lastname: Robinson
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D001665:Binding Sites; D004247:DNA / Q000235:genetics; D006133:Growth Substances / Q000235:genetics / Q000378:metabolism / Q000493:pharmacokinetics; D006168:Guinea Pigs; D008297:Male; D008657:Metabolic Clearance Rate; D008969:Molecular Sequence Data; D009154:Mutation; D010959:Tissue Plasminogen Activator / Q000235:genetics / Q000378:metabolism / Q000493:pharmacokinetics*
chemical_list: D006133:Growth Substances; D004247:DNA; D010959:Tissue Plasminogen Activator