title: Immunomodulation with bacterial extracts in respiratory diseases.
abstract: A lyophilized bacterial extract (Broncho-Vaxom) has been studied in a large number of models and found to induce specific and nonspecific responses by oral administration. It stimulates the systemic and local immune response. It activates the macrophages that play a key part in the immune system, modulates the immunoglobulin level, and potentiates the lymphocyte response to phytohemagglutinin (PHA) and other mitogens. The effect of this bacterial extract on T-lymphocyte subpopulations is currently under study.
authors.affiliation: Center of Hematology and Immunology (INIC), Faculty of Medicine, Lisbon, Portugal.
authors.forename: A G
authors.initials: AG
authors.lastname: Palma-Carlos
authors.forename: M L
authors.initials: ML
authors.lastname: Palma-Carlos
mesh_terms: D006801:Humans; D000276:Adjuvants, Immunologic / Q000008:administration & dosage; D000284:Administration, Oral; D001249:Asthma / Q000276:immunology / Q000628:therapy; D001419:Bacteria; D007108:Immune Tolerance / Q000187:drug effects; D007074:Immunoglobulin G / Q000096:biosynthesis; D007075:Immunoglobulin M / Q000096:biosynthesis; D012008:Recurrence; D012141:Respiratory Tract Infections / Q000276:immunology / Q000628:therapy; D000095983:Bacterial Lysates
chemical_list: D000276:Adjuvants, Immunologic; D007074:Immunoglobulin G; D007075:Immunoglobulin M; C030259:Broncho-Vaxom; D000095983:Bacterial Lysates