title: Emergency treatment with recombinant tissue plasminogen activator of pulmonary embolism in a pregnant woman with antithrombin III deficiency.
abstract: Thromboembolic complications during pregnancy are frequent in patients with congenital antithrombin III deficiency. We report on a 29-year-old patient with congenital antithrombin III deficiency and severe pulmonary embolism treated with recombinant tissue plasminogen activator. The diagnosis of antithrombin deficiency is retrospective. This case indicates that the risk of thrombolytic therapy in this clinical setting might have been overemphasized.
authors.affiliation: Department of Haematology, Ospedale Niguarda Cà Granda, Milano, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Baudo
authors.forename: T M
authors.initials: TM
authors.lastname: Caimi
authors.forename: R
authors.initials: R
authors.lastname: Redaelli
authors.forename: A M
authors.initials: AM
authors.lastname: Nosari
authors.forename: M
authors.initials: M
authors.lastname: Mauri
authors.forename: G
authors.initials: G
authors.lastname: Leonardi
authors.forename: F
authors.initials: F
authors.lastname: deCataldo
mesh_terms: D000328:Adult; D020152:Antithrombin III Deficiency; D004630:Emergencies; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D008297:Male; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy*; D011655:Pulmonary Embolism / Q000188:drug therapy*; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage*
chemical_list: D010959:Tissue Plasminogen Activator