title: [Value of the fetal biophysical profile in intensive monitoring of high risk pregnancy].
abstract: The fetal biophysical profile (FBP) is a combination of both acute and chronic condition markers of the fetus in the uterus (fetal movements, fetal breathing movements, amniotic fluid volume, maturity of the placenta, intestine distension, cardiotocographic "non stress test", cardiotocographic "oxytocin stress test" cardiotocographic "physical stress test") presented numerically, is an irreplaceable method for monitoring the condition of the fetus in the uterus. In 271 women with high risk pregnancies at the gestational age of 34-44 weeks, depending on the FBP value, the time and mode of pregnancy termination were chosen. There is a significant difference regarding the outcome of pregnancy (general bad outcome--p less than 0.001, mortality--p less than 0.004, low 5 min Apgar score--p less than 0.002, fetal distress during labour--p less than 0.001) depending on the FBP value (normal or pathological) and the connection of the pathological FBP values with the low fetal biochemical profile values (estriol in 24th urine less than 40,000 n mol/day and HPL less than 5 mg). Sensitivity (46.4%), specificity (99.2%), the prognostic value of the pathological test PVP (86.7%), and prognostic value of the normal test - PVN (94.1%) show a high FBP value as a diagnostic test. It is necessary to stick to the protocol while using this test which is very simple, cheap and not at all harmful.
authors.affiliation: Ginekolosko-akuserska Klinika Narodni front, Medicinskog fakulteta, Univerziteta u Beogradu.
authors.forename: A
authors.initials: A
authors.lastname: Marković
authors.forename: D
authors.initials: D
authors.lastname: Antić
authors.forename: M
authors.initials: M
authors.lastname: Dukić
authors.forename: V
authors.initials: V
authors.lastname: Rajković
mesh_terms: D001034:Apgar Score; D005260:Female; D005313:Fetal Death; D005316:Fetal Distress / Q000175:diagnosis; D005323:Fetal Monitoring; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011248:Pregnancy Complications; D012307:Risk Factors
vernacular_title: Pouzdanost biofizickog profila ploda u intenzivnoj kontroli visoko rizicnih trudnoća.