title: [A comparison of three different techniques for measuring glomerular filtration rate].
abstract: The clearance of inulin, creatinine and radioactive tracers from the blood may be used to measure glomerular filtration rate (GFR). These techniques, however, are usually invasive and time-consuming. Although the clearance of a radioactive tracer is usually applied in nuclear medicine for the determination of GFR, it is also possible to convert the concentration of the tracer in the kidneys to absolute GFR by means of a regression equation. As this new technique is much faster, we have compared it with the conventional technique. A good correlation was found with the standard radionuclide techniques (r = 0.91), but the reference method was under-estimated on the average by 14 ml/min. The new regression equation derived in our clinic will ensure future accurate GFR measurements within 6 minutes.
authors.affiliation: Departement Biofisika en Kerngeneeskunde, Universiteit van die Oranje-Vrystaat, Bloemfontein.
authors.forename: C P
authors.initials: CP
authors.lastname: Herbst
authors.forename: M
authors.initials: M
authors.lastname: Dunn
authors.forename: A C
authors.initials: AC
authors.lastname: Viviers
authors.forename: M
authors.initials: M
authors.lastname: van Zyl
authors.forename: A
authors.initials: A
authors.lastname: van Aswegen
authors.forename: A C
authors.initials: AC
authors.lastname: Otto
mesh_terms: D002860:Chromium Radioisotopes; D004492:Edetic Acid; D005919:Glomerular Filtration Rate; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging*; D004369:Pentetic Acid; D011877:Radionuclide Imaging; D012044:Regression Analysis; D013667:Technetium; D013997:Time Factors
chemical_list: D002860:Chromium Radioisotopes; D013667:Technetium; D004369:Pentetic Acid; D004492:Edetic Acid
vernacular_title: 'n Vergelyking van drie verskillende tegnieke vir die berekening van glomerulêre filtrasiespoed.