title: Effect of D-mannose on motility, presence of flagella, and attachment of Pseudomonas aeruginosa to chicken skin cells.
abstract: Treatment of Pseudomonas aeruginosa with 1 to 3% d-mannose reduced cell activity indicating the flagella were affected by d-mannose but did not decrease attachment to chicken skin cells. Distance of migration of P. aeruginosa through a hollow tube filled with 1 to 4% d-mannose was reduced when compared with 0% d-mannose. This reduced movement through the tube indicated a possible affect on the flagella. Examination of P. aeruginosa with a light microscope showed that the addition of 1, 2, 3, and 4% d-mannose to a solution containing the organism removed the flagella from 27 to 40% of the cells.
authors.affiliation: Department of Poultry Science, University of Maryland, College Park 20742.
authors.forename: J A
authors.initials: JA
authors.lastname: DeGraft-Hanson
authors.forename: J L
authors.initials: JL
authors.lastname: Heath
mesh_terms: D000818:Animals; D001422:Bacterial Adhesion / Q000187:drug effects*; D002465:Cell Movement / Q000187:drug effects*; D002645:Chickens; D005407:Flagella / Q000187:drug effects*; D008358:Mannose / Q000008:administration & dosage / Q000494:pharmacology*; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D012867:Skin / Q000166:cytology / Q000382:microbiology*
chemical_list: D008358:Mannose