Isolation and characterization of HIV-2ben obtained from a patient with predominantly neurological defects.
A HIV-2 strain named HIV-2ben was isolated from peripheral blood lymphocytes of a patient who, since 1984, had developed neurological symptoms such as Raynaud's syndrome, followed by paresthesia of extremities and ataxia, and finally paraparesis of the legs and incontinence. This new isolate could be distinguished from HIV-2rod by antibody-binding epitopes, peptide maps of core p24 and p18 polypeptides and restriction endonuclease cleavage pattern.
Schneider
J
J
German Primate Center, Göttingen, FRG.
Lüke
W
W
Kirchhoff
F
F
Jung
R
R
Jurkiewicz
E
E
Stahl-Hennig
C
C
Nick
S
S
Klemm
E
E
Jentsch
K D
KD
Hunsmann
G
G
D000818:Animals; D015683:Gene Products, gag / Q000032:analysis; D016655:HIV Core Protein p24; D015498:HIV-2 / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D009422:Nervous System Diseases / Q000382:microbiology*; D010449:Peptide Mapping; D011817:Rabbits; D014758:Viral Core Proteins / Q000032:analysis
D015683:Gene Products, gag; D016655:HIV Core Protein p24; D014758:Viral Core Proteins