title: Isolation of Leishmania sp. from aqueous humor of a patient with cutaneous disseminated leishmaniasis and bilateral iridocyclitis (preliminary report).
abstract: The authors report an uncommon case of leishmaniasis with disseminated cutaneous lesions, systemic manifestations and ocular involvement, the latter being characterized by bilateral nongranulomatous iridocyclitis. The severity of the ophthalmologic lesions and its unresponsiveness to therapy (in spite of satisfactory regression of both systemic and cutaneous manifestations) lead to a needle aspiration of the anterior eye chamber content. From this material Leishmania sp was isolated. To our knowledge this is the first time that Leishmania has been shown into the ocular globe.
authors.affiliation: Departamento de Clínica Médica, Faculdade de Medicina, UFMG, Brasil.
authors.forename: T C
authors.initials: TC
authors.lastname: Ferrari
authors.forename: A C
authors.initials: AC
authors.lastname: Guedes
authors.forename: F
authors.initials: F
authors.lastname: Oréfice
authors.forename: O
authors.initials: O
authors.lastname: Genaro
authors.forename: S R
authors.initials: SR
authors.lastname: Pinheiro
authors.forename: M A
authors.initials: MA
authors.lastname: Marra
authors.forename: I L
authors.initials: IL
authors.lastname: Silveira
authors.forename: M O
authors.initials: MO
authors.lastname: Miranda
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000818:Animals; D001082:Aqueous Humor / Q000469:parasitology*; D006801:Humans; D015863:Iridocyclitis / Q000150:complications* / Q000188:drug therapy; D007891:Leishmania / Q000302:isolation & purification*; D007896:Leishmaniasis / Q000150:complications*; D008264:Macrophages / Q000469:parasitology; D008297:Male; D008875:Middle Aged
chemical_list: D000666:Amphotericin B