Significance of 5 alpha-androstane-3 alpha, 17 beta-diol in submandibular gland.
5 alpha-Androstane-3 alpha, 17 beta-diol (3 alpha-diol) was measured in the submandibular gland (SMG) of male and female rats by radioimmunoassay (RIA) at 4 and 7 weeks of age. The raised and constant concentration of 3 alpha-diol was revealed in female SMG. The mean values of 3 alpha-diol in female SMG were found to be significantly higher than testosterone (T) and dihydrotestosterone (DHT). 3 alpha-diol in male SMG was similar to that of DHT and these two steroids decreased by the 7th week.
Tarui
M
M
Kanagawa Dental College, Japan.
Koshika
S
S
Nishimura
T
T
Yoneda
T
T
Nakayama
Y
Y
D015113:Androstane-3,17-diol / Q000032:analysis*; D000818:Animals; D013196:Dihydrotestosterone / Q000032:analysis; D005260:Female; D008297:Male; D051381:Rats; D012737:Sex Factors; D013363:Submandibular Gland / Q000737:chemistry*; D013739:Testosterone / Q000032:analysis
D013196:Dihydrotestosterone; D015113:Androstane-3,17-diol; D013739:Testosterone