Downstream regulatory elements stimulate expression of the human apolipoprotein E gene in the liver and suppress expression in the kidney of transgenic mice.
Simonet
W S
WS
Gladstone Foundation Laboratories for Cardiovascular Disease, Department of Physiology, University of California, San Francisco 94140-0608.
Bucay
N
N
Lauer
S J
SJ
Pitas
R E
RE
Weisgraber
K H
KH
Taylor
J M
JM
D000818:Animals; D001057:Apolipoproteins E / Q000096:biosynthesis / Q000235:genetics*; D003360:Cosmids; D005260:Female; D005786:Gene Expression Regulation; D005809:Genes, Regulator; D006801:Humans; D007150:Immunohistochemistry; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D008822:Mice, Transgenic; D011247:Pregnancy; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D014018:Tissue Distribution
D001057:Apolipoproteins E; D012333:RNA, Messenger