title: Change of genetic expression by physical compression forces.
abstract: Despite intense investigation of transmembrane signalling mediated by lymphocyte surface molecules, the subcellular mechanisms responsible for these phenomena remain poorly understood (Kishimoto, T. et al., 1983). In the present study, an answer for the mechanism is demonstrated by using human B blastoid cell line (CESS) which has IgG and Interleukin 6 (IL-6) receptors on the cell surface and produces IgG in response to IL-6 without any requirement for proliferation (Muraguchi, A. et al., 1981).
authors: Miki Clinic, Osaka, Japan.
authors: Y
authors: Y
authors: Miki
authors: S
authors: S
authors: Miki
mesh_terms: D000818:Animals; D000943:Antigens, Differentiation / Q000378:metabolism; D002455:Cell Division; D002478:Cells, Cultured; D005455:Fluorescent Antibody Technique; D005786:Gene Expression Regulation; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis / Q000235:genetics*; D015850:Interleukin-6 / Q000494:pharmacology*; D008214:Lymphocytes / Q000378:metabolism*; D011961:Receptors, Fc / Q000378:metabolism; D017452:Receptors, IgG; D011971:Receptors, Immunologic / Q000378:metabolism; D019947:Receptors, Interleukin-6; D012756:Sheep; D015398:Signal Transduction
chemical_list: D000943:Antigens, Differentiation; D007074:Immunoglobulin G; D015850:Interleukin-6; D011961:Receptors, Fc; D017452:Receptors, IgG; D011971:Receptors, Immunologic; D019947:Receptors, Interleukin-6