[Experience in the therapy of acne with topical administration of spironolactone as an antiandrogen].
The authors report their clinical experience with topical treatment of seborrheic acne with a 5% spironolactone cream in 20 patients, 11 males and 9 females aged 12 to 28 years (average 20.5). Treatment duration, about one month. Treatment proved remarkably effective in that it brought about complete regression of acne in 30%, improvement in 65% of the patients. The drug was always well tolerated, side effects were never observed.
Califano
L
L
Istituto di Dermatologia, Università degli Studi di Messina.
Cannavò
S
S
Siragusa
M
M
Girardi
R
R
D000152:Acne Vulgaris / Q000097:blood / Q000188:drug therapy*; D000293:Adolescent; D000328:Adult; D002648:Child; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D008297:Male; D009824:Ointments; D013148:Spironolactone / Q000008:administration & dosage* / Q000009:adverse effects; D013739:Testosterone / Q000097:blood; D013997:Time Factors
D009824:Ointments; D013148:Spironolactone; D013739:Testosterone
Esperienze nella terapia dell'acne con un trattamento topico antiandrogeno a base di spironolattone.