[A comparative evaluation between streptokinase and r-TPA in limiting the myocardial damage during an acute myocardial infarct. An echocardiographic study].
Once the experience of GISSI I was concluded, the as yet unresolved problem of the choice of one fibrinolytic agent in preference to others emerged. In the present study, the authors used echocardiography in order to compare streptokinase with r-TPA in order to limit myocardial damage in acute myocardial infarction in 33 patients, average age 64.6 years. No statistically significant difference between the two drugs was observed as far as left ventricular contractility and extent of the infarcted region was concerned. This was in accordance with the findings of the Italian PAIMS study.
Morelloni
S
S
Servizio di Cardiologia, Ospedale S. Giacomo, Novi Ligure.
Fasciolo
L
L
Freggiaro
V
V
Corazza
M
M
Pareti
G
G
Davi
R
R
Allegri
M
M
D004452:Echocardiography; D006801:Humans; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D011994:Recombinant Proteins / Q000627:therapeutic use; D013300:Streptokinase / Q000627:therapeutic use*; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*; D016277:Ventricular Function, Left / Q000187:drug effects
D011994:Recombinant Proteins; D013300:Streptokinase; D010959:Tissue Plasminogen Activator
Valutazione comparativa tra streptokinasi ed r-TPA nella limitazione del danno miocardico in corso di infarto miocardico acuto. Indagine ecocardiografica.