title: Molecular weight determination of underivatized oligodeoxyribonucleotides by positive-ion matrix-assisted ultraviolet laser-desorption mass spectrometry.
abstract: A Wiley-McLaren type time-of-flight mass spectrometer has been used for molecular weight measurements of several unprotected oligodeoxyribonucleotides using matrix-assisted UV laser desorption. Approximately 10 to 100 pmol of sample was required for recording their positive-ion mass spectra with a mass resolution in the range of 150 to 300 (Full width at half maximum) (FWHM). Little fragmentation was observed.
authors: Department of Pharmacology and Molecular Sciences, Middle Atlantic Mass Spectrometry Facility, Johns Hopkins University School of Medicine, Baltimore, MD 21205.
authors: B
authors: B
authors: Spengler
authors: Y
authors: Y
authors: Pan
authors: R J
authors: RJ
authors: Cotter
authors: L S
authors: LS
authors: Kan
mesh_terms: D013058:Mass Spectrometry / Q000295:instrumentation / Q000379:methods; D008970:Molecular Weight; D009838:Oligodeoxyribonucleotides
chemical_list: D009838:Oligodeoxyribonucleotides