[Factors influencing cerebral perfusion and their role in the development of cerebral circulatory disturbances].
Factors increasing blood viscosity grow in importance when the blood flow is reduced. Hemorheological parameters determining blood viscosity include hematocrit (Htc), red cells aggregation, red cell deformability, platelet aggregation and plasma viscosity. Platelet abnormalities seem to underlie transient ischemic attacks whereas Htc and plasma viscosity probably play an important role in complete stroke. Present therapeutic methods of stroke base, in large part, on the isovolemic or hypervolemic hemodilution, which lead to reduction of Htc. The problem of optimal value of Htc which should be achieved for improving cerebral blood flow and a sort of the plasma expander has been opened for discussion.
Kowal
P
P
Katedry Neurologii AM, Poznaniu.
D001809:Blood Viscosity / Q000502:physiology; D002560:Cerebrovascular Circulation / Q000502:physiology; D002561:Cerebrovascular Disorders / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D006438:Hemodilution; D006801:Humans
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