[The protein-binding properties of Treponema].
A new type of substances is described, related to T. pallidum cultural strain structure and interacting with human and animal blood serum proteins, named T-PBC. T-PBC were found to react with albumin, immunoglobulins G, M, and A, fibronectin, CIg component of human blood serum complement, goat and bovine blood serum immunoglobulins. When injected to animals, T-PBC induced production of specific antibodies identifying 4 components in T-PBC, 2 of these components being resistant to heating at 100 degrees C for 5 min. All these components could be stained with protein stains.
Rasskazov
N I
NI
Chalov
V V
VV
Ermolin
G A
GA
D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood; D000918:Antibody Specificity; D001426:Bacterial Proteins / Q000032:analysis / Q000276:immunology / Q000302:isolation & purification / Q000378:metabolism*; D001798:Blood Proteins / Q000187:drug effects / Q000378:metabolism*; D002846:Chromatography, Affinity; D006801:Humans; D005779:Immunodiffusion; D007122:Immunoelectrophoresis; D011485:Protein Binding / Q000187:drug effects; D014210:Treponema pallidum / Q000032:analysis / Q000276:immunology / Q000378:metabolism*
D000907:Antibodies, Bacterial; D001426:Bacterial Proteins; D001798:Blood Proteins
Izuchenie proteinsviazyvaiushchikh svoĭstv treponemy.