[Immunoelectronmicroscopic characterization of a subpopulation of Langerhans cells bearing the CD23 antigen].
The present study demonstrates that a consistent percentage (over 30%) of freshly isolated human Langerhans cells express the CD23 moiety. This was achieved employing a pre-embedding immunoelectronmicroscopy, using the peroxidase reaction product as a marker, assay on suspended trypsinized epidermal cells isolated from normal human skin. The possibility that the CD23 molecule on the surface of Langerhans cells could play a role in the antigen-presentation function of dendritic epidermal cells to T lymphocytes is proposed.
Ferrari
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C
Istituto di Istologia ed Embriologia Generale Università degli Studi di Parma.
Scandroglio
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R
Torresani
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C
D015703:Antigens, CD / Q000032:analysis*; D000944:Antigens, Differentiation, B-Lymphocyte / Q000032:analysis*; D006801:Humans; D007124:Immunoenzyme Techniques; D007801:Langerhans Cells / Q000276:immunology / Q000648:ultrastructure*; D016253:Microscopy, Immunoelectron; D011961:Receptors, Fc / Q000032:analysis*; D017455:Receptors, IgE; D012867:Skin / Q000166:cytology
D015703:Antigens, CD; D000944:Antigens, Differentiation, B-Lymphocyte; D011961:Receptors, Fc; D017455:Receptors, IgE
Caratterizzazione immunoelettronmicroscopica di una sottopopolazione di cellule di Langerhans portatrice dell'antigene CD23.