title: [Ovarian tumors located in the hilus. Analysis of 126 publications of the literature].
abstract: One hundred and twenty six reported cases of ovarian tumors located in the hilus (OTLH) are analyzed. They represent a special sub group of ovarian steroid cell tumors (former "lipid cell tumors"). A number of these neoplasms are Leydig-Berger cell tumors (LBCT), which are characterized by the presence of the crystal of Reinke, a specific proteinaceous inclusion, whose detection may be improved by new available methods. Crystal-free steroid cell tumors located in the hilus are in most cases true leydigoma of the ovary whose features are indiscernible from LBCT's. They are revealed after years of evolution by signs of hyperandrogeny or post menopausal bleeding. Plasma testosterone levels are always elevated while urinary 17 keto steroid cytoplasmic values are normal in 50% of cases. Three main features distinguish ovarian tumors located in the hilus from others ovarian steroid cell tumors: the occurrence in aged women, the small size of the tumors, and the excellent prognosis.
authors: Clinique des Maladies Endocriniennes et Métaboliques, Hôpital Cochin, Paris.
authors: J
authors: J
authors: Clerc
authors: M
authors: M
authors: Vacher-Lavenu
authors: V
authors: V
authors: Paoli
authors: C
authors: C
authors: Basin
authors: J P
authors: JP
authors: Luton
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006801:Humans; D007984:Leydig Cell Tumor / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery
vernacular_title: Tumeurs ovariennes de siège hilaire. Analyse des 126 publications de la littérature.