Surfactant maturation and preterm premature membrane rupture: a case study.
Preterm premature membrane rupture (PPROM) is known to accelerate fetal lung surfactant maturation. The mechanism for this is unclear. We report a case of prolonged PPROM, where the maturation of fetal surfactant was studied in detail by the serial analysis of surfactant phospholipids in the drained liquor.
James
D K
DK
University Department of Obstetrics, Bristol Maternity Hospital, UK.
Eddowes
H
H
Rodgers
A
A
Harkes
A
A
Williams
M
M
D000328:Adult; D000653:Amniotic Fluid / Q000378:metabolism; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000378:metabolism*; D005865:Gestational Age; D006801:Humans; D010713:Phosphatidylcholines / Q000378:metabolism; D010715:Phosphatidylglycerols / Q000378:metabolism; D010716:Phosphatidylinositols / Q000378:metabolism; D011247:Pregnancy; D011663:Pulmonary Surfactants / Q000378:metabolism*; D013109:Sphingomyelins / Q000378:metabolism
D010713:Phosphatidylcholines; D010715:Phosphatidylglycerols; D010716:Phosphatidylinositols; D011663:Pulmonary Surfactants; D013109:Sphingomyelins