title: Studies on outbreak of viral hepatitis at Calcutta with special reference to serological investigations.
abstract: Sixty cases of acute viral hepatitis were studied from clinical, biochemical and in particular serological point of view. Majority of the patients had significant pre-icteric and icteric phase with moderate elevations of bilirubin, SGOT and SGPT and marginal elevations of serum alkaline phosphatase. Cholestatic features were observed only in 6.7% of cases. All subjects improved and there was no death in this series. Serological marker studies revealed hepatitis A in 8 (13.3%) cases and hepatitis B in 3 (5.0%) cases. Rest 49 cases were possibly due to non-A, non-B hepatitis. As there was no evidence of parenteral transmission, it was concluded that this epidemic was water borne from contaminated municipal water supply.
authors: Department of Medicine, Calcutta National Medical College and Hospital.
authors: T K
authors: TK
authors: Biswas
authors: A K
authors: AK
authors: Das
authors: G C
authors: GC
authors: Shaw
authors: N
authors: N
authors: Mukherjee
authors: M
authors: M
authors: Chakraborty
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006506:Hepatitis A / Q000453:epidemiology; D006508:Hepatitis Antibodies / Q000032:analysis; D006509:Hepatitis B / Q000453:epidemiology; D006526:Hepatitis C / Q000453:epidemiology; D006525:Hepatitis, Viral, Human / Q000453:epidemiology* / Q000276:immunology; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged
chemical_list: D006508:Hepatitis Antibodies