[Thyroid disease in progressive systemic sclerosis].
There is no agreement wither thyroid disease is a common feature of progressive systemic sclerosis (PSS). We evaluated 28 patients with proven PSS with determinations of T3, T4, TSH and Tg as well as antimicrosomal autoantibodies. Radioactive I uptake, thyroid scintigraphy, TRH test and fine needle biopsy were performed in selected patients. Twelve (43%) patients had clinical or laboratory evidence of thyroid dysfunction. Four patients had euthyroid goiter, 3 had evidence of autoimmune disease, 2 had chronic Hashimoto's thyroiditis, 1 was hypothyroid, 1 hyperthyroid and one has subacute thyroiditis. The CREST variant of PSS was most commonly associated with thyroid pathology. Our results indicated that thyroid disease is frequently associated to PSS. A complete clinical and laboratory evaluation is needed to confirm its presence.
Besançon
M F
MF
Servicio de Medicina, Hospital del Salvador, Universidad de Chile, Santiago.
Guzmán
L
L
Grisanti
M
M
Basualdo
J
J
Alvarado
M A
MA
Rendic
O
O
Pineda
G
G
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000097:blood / Q000150:complications*; D013959:Thyroid Diseases / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D013960:Thyroid Function Tests
Patología tiroídea en la esclerosis sistémica progresiv a.