Squamous cell carcinoma arising from a chronic osteomyelitis of the ankle region.
Prolonged, persistent infection may, on occasion, develop into malignant pathology. Dr. Wu describes a case where squamous cell carcinoma resulted from open reduction of an ankle fracture. The pathology may initiate from the epithelialized lining of the sinus tract and bone cavity.
Wu
K K
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Henry Ford Hospital, Detroit, Michigan.
D016512:Ankle Injuries; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology; D005597:Fractures, Open / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000150:complications* / Q000209:etiology; D012983:Soft Tissue Neoplasms / Q000209:etiology* / Q000473:pathology