[Modification of selected lipoproteins and blood pressure by different dosages of n-3-fatty acids].
125 male patients with cardiovascular diseases (51.0 +/- 5.1 years) were treated with supplementary fish oil diet (gelatin capsules 2 g or 6 g PUFA/a day) and arachis oil gelatin capsules, respectively, as well as simultaneous fat- and energy-reduced diet at a moderate body-training during a four-week cure. N-3 PUFA-rich fish oil diet caused a significant decrease of the triglycerides and the Apo B with increase of the HDL2 cholesterol. By addition of reduction diet the effect became clearer by additional ascertained decrease of total and LDL-cholesterol. The blood pressure-reducing effect of n-3 PUFA, but not n-6 PUFA, at test as well as on exertion was present with 2 g and 6 g/a day, however, it was more conspicuous with the higher dosage.
Biermann
J
J
Sanatorium Dr. Kurt Fischer, Bad Colberg.
Herrmann
W
W
D000787:Angina Pectoris / Q000097:blood / Q000628:therapy*; D016632:Apolipoprotein A-I; D001054:Apolipoproteins A / Q000097:blood; D001055:Apolipoproteins B / Q000097:blood; D001794:Blood Pressure / Q000187:drug effects*; D002214:Capsules; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003131:Combined Modality Therapy; D003327:Coronary Disease / Q000097:blood / Q000628:therapy*; D004038:Diet, Reducing; D015525:Fatty Acids, Omega-3 / Q000008:administration & dosage*; D005231:Fatty Acids, Unsaturated / Q000008:administration & dosage; D005395:Fish Oils / Q000008:administration & dosage*; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000628:therapy*; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D014280:Triglycerides / Q000097:blood
D016632:Apolipoprotein A-I; D001054:Apolipoproteins A; D001055:Apolipoproteins B; D002214:Capsules; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D015525:Fatty Acids, Omega-3; D005231:Fatty Acids, Unsaturated; D005395:Fish Oils; D008074:Lipoproteins; D014280:Triglycerides; D002784:Cholesterol
Zur Beeinflussung ausgewählter Lipoproteine und des Blutdrucks durch unterschiedliche Dosierung von n-3-Fettsäuren.