Histomorphometric results after late microsurgical nerve grafting of the inferior alveolar nerve of the rabbit.
An experimental study was conducted to evaluate the regenerative potential of the inferior alveolar nerve after nerve transection and microsurgical reconstruction at different intervals. Histomorphometric parameters of regenerating axons were assessed using a computer-assisted image analysis system. A continuous decrease in axon density and a reduction in axon diameter was noted in all groups. The average regeneration rate ranged from 42% to 60%. The results of this study indicate that microsurgical reconstruction of the inferior alveolar nerve is even possible 12 months after nerve transection.
Eckardt
A
A
Dept. of Oral and Maxillofacial Surgery, Medizinische Hochschule Hannover, West Germany.
Meier
K
K
Hausamen
J E
JE
D000714:Anastomosis, Surgical; D000818:Animals; D001369:Axons / Q000502:physiology* / Q000648:ultrastructure; D007091:Image Processing, Computer-Assisted; D008297:Male; D008340:Mandibular Nerve / Q000503:physiopathology / Q000601:surgery* / Q000648:ultrastructure; D008866:Microsurgery; D009186:Myelin Sheath / Q000648:ultrastructure; D009412:Nerve Fibers / Q000473:pathology / Q000502:physiology; D009413:Nerve Fibers, Myelinated / Q000473:pathology / Q000502:physiology; D009416:Nerve Regeneration / Q000502:physiology*; D011817:Rabbits; D013979:Tibial Nerve / Q000637:transplantation; D013997:Time Factors