title: [Genotoxic study of commercial dyes with tartrazine base in S. typhimurium his- and E. coli trp-].
abstract: We study the genotoxic character of 21 food dyes samples with tartrazine in different trade-marks. Two homologated assays "in vitro" of reverse mutation in S. typhimurium and E. coli are used, with metabolic activation. There is no evidence of mutagenic character in any sample.
authors: Departamento de Toxicología, Instituto de Salud Carlos III.
authors: M T
authors: MT
authors: Pollastrini
authors: M
authors: M
authors: Barea
authors: J
authors: J
authors: Salas
mesh_terms: D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics; D006639:Histidine / Q000235:genetics; D009152:Mutagenicity Tests; D009154:Mutation / Q000187:drug effects*; D012486:Salmonella typhimurium / Q000187:drug effects* / Q000235:genetics; D013645:Tartrazine / Q000494:pharmacology / Q000633:toxicity*; D014364:Tryptophan / Q000235:genetics
chemical_list: D006639:Histidine; D014364:Tryptophan; D013645:Tartrazine
vernacular_title: Estudio genotóxico de colorantes comerciales con base Tartracina en S. typhimurium his- y E. coli trp-.