title: Tooth and bone tissue analysis by element mapping spectrometry.
abstract: Elemental analyses of the tooth and bone tissues were carried out by X-ray fluorescence element mapping spectrometry, a technique we have recently developed. This analytical system has the advantage of providing data on distribution of element concentration in a given specimen in overhead view without involving destruction of the tissue architecture. This paper briefly introduces the apparatus of this system and presents analytical data obtained for several elements (calcium, iron, arsenic, zinc and strontium) in the tooth and bone tissues of rats bearing tumor induced with lead acetate. Lead distributed in the maxillary incisive bone and femur was demonstrated in rats with lead acetate-induced tumor sacrificed at 42 weeks after injections. Arsenic observed in the femur of control rats was found replaced by lead in the tumor bearing rats. The findings are of interest as viewed with reference to chelating activity of lead.
authors: Department of Histology, Nippon Dental University School of Dentistry at Niigata.
authors: Y
authors: Y
authors: Teraki
authors: A
authors: A
authors: Uchiumi
mesh_terms: D000818:Animals; D001151:Arsenic / Q000032:analysis; D001842:Bone and Bones / Q000737:chemistry*; D005269:Femur / Q000737:chemistry; D007854:Lead / Q000032:analysis*; D008297:Male; D008437:Maxilla / Q000737:chemistry; D009374:Neoplasms, Experimental / Q000139:chemically induced; D009942:Organometallic Compounds; D051381:Rats; D011916:Rats, Inbred F344; D013050:Spectrometry, Fluorescence / Q000379:methods; D014070:Tooth / Q000737:chemistry*
chemical_list: D009942:Organometallic Compounds; D007854:Lead; D001151:Arsenic; C008261:lead acetate