Branched-chain amino acid enriched diet given simultaneously with ethanol partially prevents morphological and biochemical changes in the liver.
Morphological examination of the liver and biochemical studies of the serum were carried out on rats fed: a) ethanol p.o. in the daily dose of 6 g/kg for 4 weeks and maintained on standard diet (Et-OH) and b) ethanol in the same doses but fed the BCAA enriched diet (to amount of 1.174 mM/day/rat) were carried out. It can be concluded that BCAA enriched diet given simultaneously with ethanol prevent in part the morphological and ultrastructural changes in liver and improve positive body weight gain of experimental animals.
Farbiszewski
R
R
Department of Inorganic and Analytical Chemistry, Medical Academy, Białystok.
Chyczewski
L
L
Hołownia
A
A
Pawłowska
D
D
Chwiećko
M
M
D000597:Amino Acids, Branched-Chain / Q000008:administration & dosage*; D000818:Animals; D005527:Food, Fortified; D008099:Liver / Q000648:ultrastructure; D008108:Liver Diseases, Alcoholic / Q000201:enzymology / Q000517:prevention & control*; D008297:Male; D008854:Microscopy, Electron; D051381:Rats; D017208:Rats, Wistar; D000637:Transaminases / Q000378:metabolism
D000597:Amino Acids, Branched-Chain; D000637:Transaminases