title: Serum esterase activities and hyperlipidaemia in the streptozotocin-diabetic rat.
abstract: The levels of activity of four serum esterases were measured in control and streptozotocin-diabetic rats for a period of 6 months. Pseudocholinesterase activity was significantly elevated in the diabetic rats at all time points tested, reaching 250% of the control activity at 6 months. Levels of paraoxonase activity progressively decreased with time in the diabetic rats, being 36% lower than in controls at 6 months. No significant differences in either serum arylesterase or carboxylesterase activity between control and diabetic rats were observed.
authors: Department of Biochemistry and Molecular Biology, University of Manchester Medical School, U.K.
authors: B N
authors: BN
authors: Patel
authors: M I
authors: MI
authors: Mackness
authors: D W
authors: DW
authors: Harty
authors: S
authors: S
authors: Arrol
authors: R P
authors: RP
authors: Boot-Handford
authors: P N
authors: PN
authors: Durrington
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D002784:Cholesterol / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000097:blood* / Q000139:chemically induced / Q000150:complications; D004950:Esterases / Q000097:blood*; D006949:Hyperlipidemias / Q000209:etiology*; D008297:Male; D051381:Rats; D013311:Streptozocin; D014280:Triglycerides / Q000378:metabolism
chemical_list: D001786:Blood Glucose; D014280:Triglycerides; D013311:Streptozocin; D002784:Cholesterol; D004950:Esterases