title: The relationship between suppression of acidity and gastric ulcer healing rates.
abstract: We have investigated the relationship between the suppression of acidity by antisecretory drugs for the treatment of benign gastric ulcer and their corresponding ulcer-healing rates. For a variety of antisecretory drug regimens, there was a significant correlation between suppression of 24-h intragastric acidity and ulcer healing rates after 2, 4 and 8 weeks of treatment. There was a lesser degree of correlation between healing and suppression of nocturnal acidity and the association between suppression of acidity and gastric-ulcer healing rates was less marked than that previously described for duodenal ulcer.
authors: University Department of Materia Medica, Stobhill General Hospital, Glasgow, Scotland.
authors: C W
authors: CW
authors: Howden
authors: R H
authors: RH
authors: Hunt
mesh_terms: D000863:Antacids / Q000627:therapeutic use*; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D005744:Gastric Acid / Q000502:physiology*; D006801:Humans; D015201:Meta-Analysis as Topic; D013276:Stomach Ulcer / Q000188:drug therapy*
chemical_list: D000863:Antacids; D000897:Anti-Ulcer Agents