Cysteamine does not induce gastric ulceration in rat most probably because of its endogenous prostacyclin mobilizing effect.
Balint
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GA
Department of Neurology and Psychiatry, (Clinical Pharmacology Lab.), Albert Szent-Györgyi Medical University, Hungary.
D000818:Animals; D003543:Cysteamine / Q000494:pharmacology / Q000633:toxicity*; D011464:Epoprostenol / Q000378:metabolism*; D005260:Female; D005753:Gastric Mucosa / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology; D011706:Pyloric Antrum; D051381:Rats; D011919:Rats, Inbred Strains; D013276:Stomach Ulcer / Q000139:chemically induced*
D003543:Cysteamine; D011464:Epoprostenol