T-cell lymphosarcoma in a female African green monkey (Cercopithecus aethiops).
A female African green monkey developed a generalized lymphosarcoma spontaneously that clinically and pathologically resembled malignant lymphoma in human beings infected with human T-lymphotropic virus type I. The monkey was serologically positive for simian T-lymphotropic virus. Immunocytochemical analysis of routinely fixed and paraffin embedded tumor tissue demonstrated neoplastic cells that stained positive with antihuman monoclonal UCHL1 which recognized a T-cell-restricted isotype of leukocyte common antigen.
Jayo
M J
MJ
Department of Comparative Medicine, Bowman Gray School of Medicine, Wake Forrest University, Winston-Salem, NC 27103.
Laber-Laird
K
K
Bullock
B C
BC
Tulli
H M
HM
Reynolds
G M
GM
D000818:Animals; D002522:Chlorocebus aethiops; D005260:Female; D008198:Lymph Nodes / Q000473:pathology; D008214:Lymphocytes / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology / Q000662:veterinary*; D008992:Monkey Diseases / Q000473:pathology*