Glomerulonephritis in renal transplantation.
Recurrent glomerulonephritis and de novo glomerulonephritis may develop in the graft after renal transplantation. Among 59 patients with a pathological diagnosis of glomerulonephritis as original renal disease, 12 (20.3%) showed recurrence of the original lesions in the graft. Two patients with hereditary nephritis developed anti-GBM disease (one patients in two grafts). The disease rapidly progressed to graft loss. A de novo membranous nephropathy was diagnosed in four patients whose original renal disease was not a glomerulonephritis. One patient had been treated with antilymphocyte globulin, another with captopril.
Vangelista
A
A
Institute of Nephrology, St Orsola University Hospital, Bologna, Italy.
Frascà
G M
GM
Martella
D
D
Bonomini
V
V
D000293:Adolescent; D000328:Adult; D001485:Basement Membrane / Q000276:immunology; D002648:Child; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology* / Q000601:surgery; D005923:Glomerulosclerosis, Focal Segmental / Q000209:etiology / Q000601:surgery; D006084:Graft Rejection; D006801:Humans; D007678:Kidney Glomerulus / Q000276:immunology; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012008:Recurrence