title: [Left ventricular filling in treated essential hypertension. A study using Doppler echocardiography].
abstract: The first stigmata of left ventricular involvement in hypertension are changes in diastolic filling. Early detection of these abnormalities is important as some antihypertensive agents may have beneficial effects on left ventricular distensibility and filling, in addition to lowering the blood pressure. This study compares parameters of left ventricular filling recorded by pulsed Doppler echocardiography in 44 treated hypertensives (average blood pressure: 157 +/- 20/93 +/- 12 mmHg) without any other coronary risk factors with 33 age-matched (52 +/- 13 years and 48 +/- 13 years) control normotensive subjects (average blood pressure: 130 +/- 11/80 +/- 7 mmHg). The main findings were an increase of the peak. A wave velocity after atrial contraction and of the A/E ratio in the hypertensive group (66 +/- 16 cm/s vs 53 +/- 14 cm/s, p less than 0.05 and 0.99 +/- 0.34 vs 0.78 +/- 0.24, p less than 0.05, respectively). These changes were more pronounced in patients with left ventricular hypertrophy. The rapid filling phase was unchanged (maximum E wave velocity = 68 +/- 18 cm/s vs 70 +/- 14 cm/s). The influence of age on peak A wave velocity and A/E ratio was obvious in control subjects and hypertensives without left ventricular hypertrophy r = 0.80; p less than 0.05). The age factor was not significant in the presence of left ventricular hypertrophy (r = 0.18). A weak linear correlation was observed between the peak A wave velocity, diastolic septal thickness (r = 0.44; p = 0.04) and left ventricular mass (r = 0.44; p = 0.05) in hypertensive patients with left ventricular hypertrophy.
authors: Service de cardiologie, hôpital de Hautepierre, CHRU de Strasbourg.
authors: G
authors: G
authors: Roul
authors: P
authors: P
authors: Bareiss
authors: P
authors: P
authors: Germain
authors: C
authors: C
authors: Cuny
authors: R
authors: R
authors: Arbogast
authors: J R
authors: JR
authors: Kieny
authors: A
authors: A
authors: Facello
authors: J M
authors: JM
authors: Mossard
authors: A
authors: A
authors: Sacrez
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D006332:Cardiomegaly / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D015150:Echocardiography, Doppler; D005260:Female; D006352:Heart Ventricles; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction
vernacular_title: Le remplissage ventriculaire gauche dans l'hypertension artérielle essentielle traitée. Etude par écho-doppler.