[Ecological changes in burn wound bacterial flora].
A comparative study of the ecology of the burn wound bacterial flora, during Jan. 1970 to Dec. 1971 (Group I) and Jan. 1985 to Dec. 1986 (Group II) was carried out. The incidence of Gram positive cocci was 40.70% in Group I versus 45.66% in Group II. That of Gram negative bacilli was 54.92% and 48.10% respectively. The occurrence of Ps. aeruginosa was markedly reduced, in Group I it reached 35.08% versus 11.26% in Group II (P less than 0.001). The incidence of Enterobacter aerogenes was significantly increased, in Group I it was only 3.69% but it accounted for 11.14% in Group II (P less than 0.001). Before 1972, K. pneumonia and E. cloacae were seldom found on burn wounds, in Group II, however, the incidence was 3.79% and 3.06% respectively. Acinetobacter anitratum occurred more often in Group II than in Group I, being 3.30% and 1.38% respectively (P less than 0.05). A total of 79 strains of Staphylococcus aureus were isolated from burn wounds, during Dec. 1986 to Nov. 1987. Among them Methicillin resistant Staphylococcus aureus (MRSA) accounted for 58 strains (73.4%) that is notable problem. In this centre 1% silver sulphadiazine has been used routinely since 1972 and third-generation cephalosporins have been used widely since 1983, there are the principle causes of the changing pattern of bacterial flora on the burn wounds.
Xu
W S
WS
Shanghai Burn Institute, Rui Jin Hospital, Shanghai Second Medical University.
D002056:Burns / Q000150:complications*; D004352:Drug Resistance, Microbial; D004463:Ecology; D004754:Enterobacter / Q000302:isolation & purification*; D004756:Enterobacteriaceae Infections; D006801:Humans; D016106:Methicillin Resistance; D011552:Pseudomonas Infections / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification*; D013203:Staphylococcal Infections / Q000382:microbiology; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D014946:Wound Infection / Q000209:etiology / Q000382:microbiology*