The labilizing and stabilizing effect of physostigmine on CNS.
The authors observed biphasic changes of dopamine, norepinephrine and serotonin in the rat brain stem after a single application of physostigmine (1 mg/kg of body weight). The results confirm the hypothesis of "labilization and stabilization" of membranes.
Navrátil
J
J
Department of Pathological Physiology, Medical Faculty of the Palacký University, Olomouc, Czechoslovakia.
Sklenovský
A
A
Camela
Z
Z
Rypka
M
M
D000818:Animals; D001933:Brain Stem / Q000187:drug effects* / Q000378:metabolism; D004298:Dopamine / Q000378:metabolism; D008297:Male; D009638:Norepinephrine / Q000378:metabolism; D010830:Physostigmine / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000378:metabolism
D012701:Serotonin; D010830:Physostigmine; D004298:Dopamine; D009638:Norepinephrine