Progressive pseudorheumatoid chondrodysplasia simulating juvenile rheumatoid arthritis.
Four patients from a Muslim family with an inherited skeletal dysplasia are presented. It is more crippling than usual form of spondylo-epiphysial dysplasia tarda and the onset is very early in the life i.e. at 4 years. The disorder is progressive, crippling and has striking clinical resemblance to juvenile rheumatoid arthritis. The striking X-ray appearance is of platyspondyly and irregularities of capital femoral epiphysis. There is absence of any synovitis. Two of these patients are females aged 8 years and 18 years. The third patient is their cousin brother aged 6 years and their uncle who is of 50 years old and crippled.
Archik
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Department of Orthopaedic Surgery, K.B. Bhabha Hospital, Bandra, Bombay.
Kamat
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D000293:Adolescent; D001171:Arthritis, Juvenile / Q000175:diagnosis*; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010009:Osteochondrodysplasias / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000235:genetics; D010375:Pedigree; D011859:Radiography