title: [Effect of maternal oxygenation on fetal blood gas status in shiba goat fetuses].
abstract: The purpose of this study is to investigate the effect of maternal oxygen administration on the fetal blood gas status. Five Shiba goat fetuses were used whose gestational days were 134 +/- 4 days. Maternal and fetal pH, pO2, pCO2, B.E., and hematocrit were measured every 30 minutes during 4 l/min oxygen administration for 60 minutes. Maternal arterial blood pO2 increased from 95.5 +/- 19.6 mmHg to 262.6 +/- 75.8 mmHg at 30 minutes and to 207.8 +/- 110.1 mmHg at 60 minutes. Fetal arterial blood pO2 increased significantly from 18.4 +/- 3.0 mmHg to 24.4 +/- 5.8 mmHg and 23.6 +/- 6.9 mmHg, respectively. There was a significant positive correlation between maternal pO2 and fetal pO2. The increase in fetal pO2 was small when the control pO2 was less than 17 mmHg. Although maternal pH did not change significantly, fetal pH decreased significantly from 7.29 +/- 0.07 to 7.25 +/- 0.07 at 60 minutes. Also fetal hematocrit decreased significantly from 33.9 +/- 5.2% to 32.8 +/- 5.4% at 60 minutes. Neither maternal nor fetal pCO2 and B.E. changed significantly. Therefore, we concluded that the effect of maternal oxygen administration on fetal pO2 was small when the fetus was already hypoxic. Also 60 minutes' oxygen administration may cause the decrease in fetal pH and hemodilution.
authors: Department of Obstetrics and Gynecology, Kitasato University School of Medicine, Kanagawa.
authors: H
authors: H
authors: Yoshihara
authors: T
authors: T
authors: Genda
authors: T
authors: T
authors: Hayashi
authors: H
authors: H
authors: Tatsumi
authors: N
authors: N
authors: Shimada
authors: M
authors: M
authors: Nishijima
mesh_terms: D000818:Animals; D001784:Blood Gas Analysis / Q000662:veterinary*; D001794:Blood Pressure; D002245:Carbon Dioxide / Q000097:blood; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D006041:Goats; D006340:Heart Rate, Fetal; D006400:Hematocrit; D006863:Hydrogen-Ion Concentration; D010100:Oxygen / Q000097:blood*; D010102:Oxygen Inhalation Therapy; D011247:Pregnancy
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen