Changes in circulating hormone levels after ovarian wedge resection in patients with polycystic ovary syndrome.
Serum gonadotropin, prolactin, estradiol, sex hormone binding globulin (SHBG) and androgen levels were measured before, 5 days and 6 weeks following ovarian wedge resection in 9 patients with polycystic ovary syndrome. Elevated levels of LH, androstenedione, testosterone and dehydroepiandrosterone-sulphate (DHEA-S) were found before surgery. There was a marked decrease in androstenedione and DHEA-S levels 5 days following wedge resection, but a rebound effect could be observed 6 weeks later. Serum gonadotropin, prolactin, testosterone and SHBG concentrations were practically unaffected by surgery. At 6-12 months follow up patients showed regular, mainly ovulatory cycles, but pregnancy occurred only in two cases.
Szilágyi
A
A
Department of Obstetrics and Gynecology, University Medical School of Pécs, Hungary.
Rossmanith
W
W
Csermely
T
T
Csaba
I
I
D000293:Adolescent; D000728:Androgens / Q000097:blood; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D005500:Follow-Up Studies; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D010053:Ovary / Q000601:surgery*; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000601:surgery*; D011183:Postoperative Complications / Q000097:blood*; D011388:Prolactin / Q000097:blood; D012738:Sex Hormone-Binding Globulin / Q000378:metabolism
D000728:Androgens; D012739:Gonadal Steroid Hormones; D012738:Sex Hormone-Binding Globulin; D004958:Estradiol; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone