Correlation between disc potency and zone size in temafloxacin activity in vitro.
A multi-test disc potency evaluation of a new fluoroquinolone, temafloxacin, has been prepared in order to evaluate the variation of the zone dimension with the disc antibiotic concentration. A direct correlation between these parameters has been demonstrated. All pathogens have been isolated in hospitalized patients.
Reggio
S
S
S. Anna Hospital, Rome, Italy.
Bassanetti
I
I
Ceralli
M
M
Giardini
R
R
Sansonetti
G
G
D042462:4-Quinolones; D000890:Anti-Infective Agents / Q000494:pharmacology*; D004341:Drug Evaluation; D004926:Escherichia coli / Q000187:drug effects; D024841:Fluoroquinolones; D006801:Humans; D007711:Klebsiella pneumoniae / Q000187:drug effects; D008826:Microbial Sensitivity Tests / Q000379:methods; D011513:Proteus mirabilis / Q000187:drug effects; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D015363:Quinolones; D012706:Serratia marcescens / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects
D042462:4-Quinolones; D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D015363:Quinolones; C054745:temafloxacin