Antibacterial activity of new synthesized amino-oxides and quaternary ammonium salts.
An amino oxide and three quaternary ammonium salts were investigated for antimicrobial activity. All compounds had low MIC against gram positive bacteria. Despite high MIC the ammonium salts gave good killing of Pseudomonas aeruginosa in time kill experiments. These quaternary ammonium salts may be useful for disinfection as they are easily broken down in the environment.
Cupková
V
V
Department of Biochemistry and Microbiology, Faculty of Pharmacy, Comenius University, Czechoslovakia.
Espersen
F
F
Høiby
N
N
D001419:Bacteria / Q000187:drug effects*; D004123:Dimethylamines / Q000494:pharmacology*; D004202:Disinfectants / Q000494:pharmacology*; D006801:Humans; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology*; D013211:Staphylococcus aureus / Q000187:drug effects
D004123:Dimethylamines; D004202:Disinfectants; D000644:Quaternary Ammonium Compounds; C019353:N,N-dimethyl-1-methyldodecylamine oxide