[Two cases of side effects of a fumaric acid ester--local therapy].
We report on two cases of adverse reactions to topical treatment with monoethyl fumarate. One patient suffering from atopic dermatitis reacted with contact dermatitis; the other, suffering from psoriasis, developed a generalized, partly pustulous exanthema as well as signs of systemic involvement, such as tachycardia and dyspnea. As the causative mechanism we suggest non-immunological contact urticaria syndrome.
Dücker
P
P
Krankenhäuser des Märkischen Kreises, Dermat. Abtlg., Lüdenscheid.
Pfeiff
B
B
D000287:Administration, Topical; D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced; D003875:Drug Eruptions / Q000209:etiology*; D004485:Eczema / Q000188:drug therapy*; D005260:Female; D005650:Fumarates / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D011565:Psoriasis / Q000188:drug therapy*
D005650:Fumarates; C061175:ethyl fumarate
Zwei Fälle von Nebenwirkungen einer Fumarsäureester--Lokaltherapie.