title: [Juvenile myoclonic epilepsy. Life difficulties and response to treatment].
abstract: Juvenile myoclonic epilepsy (JME) may have different forms of clinical expression and produces different kinds of life difficulties. Both eventualities have not been sufficiently described in the literature. Treatment with valproic acid is useful but requires strict compliance of medical instructions. Thirty two patients with this disease, are presented in order to describe their presenting forms, associated life handicaps and the results of their treatment. The disease may first present as tonic-clonic, complex absence or complex partial seizures, followed months or years later, by typical myoclonic crisis or as JME to which other kinds of epileptic crisis may or not be added after some time. Twenty four (75%) patients had 38 life difficulties, these being, mainly, objects dropped from hand, burns and parental aggression. Eighteen (56.25%) patients had relapses during treatment. In 14 cases (77.77%) relapses were due to noncompliance, 8 (57.19%) patients couldn't afford the cost of valproic acid. Knowledge of the presenting forms of the disease may favor opportune diagnosis and treatment, which would prevent life difficulties. Relapses are mainly due to noncompliance and economic reasons.
authors: Servicio de Neurología Infantil, Hospital Luis Calvo Mackenna.
authors: M
authors: M
authors: Devilat
authors: R
authors: R
authors: Chamorro
authors: R
authors: R
authors: Erazo
authors: L
authors: L
authors: Germain
authors: F
authors: F
authors: Mena
authors: B
authors: B
authors: Valenzuela
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000627:therapeutic use; D002648:Child; D004569:Electroencephalography; D004831:Epilepsies, Myoclonic / Q000188:drug therapy / Q000503:physiopathology* / Q000523:psychology; D006801:Humans; D011788:Quality of Life
chemical_list: D000927:Anticonvulsants
vernacular_title: Epilepsia mioclónica juvenil. Dificultades de vida y respuesta al tratamiento.