title: A new, low-incidence red cell antigen (HOFM), associated with depressed C antigen.
abstract: A case of mild hemolytic disease of the newborn is presented which was caused by an antibody to a hitherto unknown antigen of low incidence. This antigen, now designated as HOFM (ISBT number 700050) was detected in 6 relatives, and in all of them, it was associated with an unusually weakened expression of C antigen. The serological data indicate that HOFM may be part of the Rh system, but the genetic data, although supportive of this interpretation, are inconclusive.
authors: Department of Clinical Laboratories, Catharina Hospital, Eindhoven, The Netherlands.
authors: J J
authors: JJ
authors: Hoffmann
authors: M A
authors: MA
authors: Overbeeke
authors: H
authors: H
authors: Kaita
authors: A A
authors: AA
authors: Loomans
mesh_terms: D000328:Adult; D000918:Antibody Specificity / Q000276:immunology; D004899:Erythroblastosis, Fetal / Q000276:immunology*; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007519:Isoantigens / Q000032:analysis*; D008297:Male; D010375:Pedigree; D012204:Rh-Hr Blood-Group System / Q000276:immunology*
chemical_list: D007519:Isoantigens; D012204:Rh-Hr Blood-Group System