Insight into protein nuclear magnetic resonance research.
Nuclear magnetic resonance (NMR) is one of the most powerful techniques to investigate the geometry of molecules in solution. It has been widely applied, in recent years, to the study of protein conformation. However, full reconstruction of the 3-D structure of such macro-molecules, still constitutes a real challenge for the spectroscopist. Skills as diverse as biology, spectroscopy, signal processing, or computer sciences, are required. This paper presents various aspects of the research in that domain, and our contribution to it.
Stoven
V
V
Ecole Polytechnique, Laboratoire de RMN, Palaiseau, France.
Lallemand
J Y
JY
Abergel
D
D
Bouaziz
S
S
Delsuc
M A
MA
Ekondzi
A
A
Guittet
E
E
Laplante
S
S
Le Goas
R
R
Malliavin
T
T
D020418:Algal Proteins; D004546:Elapid Venoms / Q000737:chemistry; D001330:Electronic Data Processing; D005656:Fungal Proteins / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*; D012259:Ribonuclease, Pancreatic
D020418:Algal Proteins; D004546:Elapid Venoms; D005656:Fungal Proteins; D011506:Proteins; C061032:cryptogein protein, Phytophthora cryptogea; C046366:angiogenin; D012259:Ribonuclease, Pancreatic