The evolution of a clinically relevant experimental model for the realistic evaluation of long-length (80-cm) arterial prostheses.
A new carotid-femoral experimental model has been developed which has significant clinical relevance to human limb salvage bypass grafting in the areas of graft length, hemodynamics and tissue environment. More significantly, the graft healing pattern observed with this model is similar to what is seen in humans. Therefore, this experimental model provides a challenging and critical site for dynamic healing studies and comparisons of different types of vascular prostheses.
Wu
H D
HD
Hope Heart Institute, Providence Medical Center, Seattle, Washington 98122.
Arnell
R E
RE
Sauvage
L R
LR
Goff
S G
SG
Shi
Q
Q
Kaplan
S
S
Durante
K R
KR
Wechezak
A R
AR
Walker
M W
MW
D000818:Animals; D001807:Blood Vessel Prosthesis / Q000592:standards*; D002339:Carotid Arteries / Q000601:surgery*; D004285:Dogs; D005260:Female; D005263:Femoral Artery / Q000601:surgery*; D008297:Male; D008955:Models, Cardiovascular; D011093:Polyethylene Terephthalates; D011474:Prosthesis Design / Q000592:standards; D013536:Suture Techniques; D014654:Vascular Patency; D014861:Washington
D011093:Polyethylene Terephthalates