title: Failure of an intramuscular injection of an analogue of gonadotrophin-releasing hormone 11 to 13 days after insemination to increase pregnancy rates in dairy cattle.
abstract: At 11 to 13 d after insemination, 1028 dairy cows on 19 farms were given an intramuscular injection of 10 micrograms of the GnRH analogue buserelin. Their reproductive performance was compared to 1022 control cows receiving a placebo. The GnRH analogue-treated cows had fewer short interoestrous intervals compared to the control cows, but there were no significant differences in pregnancy rates to either the insemination preceding or following treatment, in calving to conception interval, or to percent pregnant by the end of mating. There were no differences between treatments in herds of high, average or low pregnancy rate, in 2-year-old cows or cows greater than 2-years-old and in cows calved 40 d or less, or greater than 40 d. The use of 10 micrograms of the GnRH analogue, buserelin, 11 to 13 d after insemination, cannot be recommended as a method of improving reproductive performance in dairy herds.
authors: University of Melbourne, Department of Veterinary Clinical Sciences, Princes Highway, Werribee, Victoria.
authors: T F
authors: TF
authors: Jubb
authors: D
authors: D
authors: Abhayaratne
authors: J
authors: J
authors: Malmo
authors: G A
authors: GA
authors: Anderson
mesh_terms: D000818:Animals; D002064:Buserelin / Q000494:pharmacology*; D002417:Cattle / Q000502:physiology*; D005260:Female; D005298:Fertility / Q000187:drug effects*; D005306:Fertilization / Q000187:drug effects; D007315:Insemination, Artificial / Q000662:veterinary; D011247:Pregnancy
chemical_list: D002064:Buserelin