The effects of caffeine and theophylline on the triple adenosine triphosphatase enzyme activities of spermatozoa from males with oligoasthenospermia.
The triple ATPase activities of washed spermatozoa of oligoasthenospermic men (but not of normals) were enhanced by the addition of caffeine and theophylline, which are known to have a stimulating effect on sperm motility. The biochemical mechanism of action of caffeine and theophylline on sperm homeostasis is discussed.
Karacagil
M
M
Department of Urology, School of Medicine, Erciyes University, Kayseri, Turkey.
Imamoğlu
A
A
Paşaoğlu
H
H
Gülmez
I
I
Tatlişen
A
A
D000251:Adenosine Triphosphatases / Q000032:analysis*; D002110:Caffeine / Q000494:pharmacology*; D006801:Humans; D008297:Male; D013081:Sperm Motility / Q000187:drug effects*; D013094:Spermatozoa / Q000201:enzymology* / Q000378:metabolism; D013806:Theophylline / Q000494:pharmacology*
D002110:Caffeine; D013806:Theophylline; D000251:Adenosine Triphosphatases