[Fetal macrosomia in a diabetic mother].
Foetal macrosomia is arbitrarily defined as an excessive weight for the gestational age, was found to be present in 36 p. 100 of 43 diabetic pregnancies. This finding may indicate incomplete normalization of maternal metabolic control despite the use of new forms of insulin delivery systems, such as insulin pumps. However, in our series the macrosomia was usually moderate and without consequences on the foetal outcome. The levels of insulin, but not those of the insulin-like growth factor (IgF1), were increased in the umbilical cord blood of macrosomic newborns of diabetic mothers. Cardiac septum hypertrophy correlated with maternal glycosylated haemoglobin levels better than with macrosomia. We therefore suggest that in all diabetic pregnancies the cardiac septum thickness should be measured in utero by sonocardiography.
Fenichel
P
P
Service d'Endocrinologie et de Diabétologie, CHU, Nice.
Hieronimus
S
S
Bourlon
F
F
Leonard
J
J
Boutte
P
P
Gillet
J Y
JY
Harter
M
M
D000328:Adult; D005260:Female; D005320:Fetal Macrosomia / Q000097:blood / Q000209:etiology*; D006343:Heart Septal Defects / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000097:blood / Q000150:complications*
Macrosomie du foetus de mère diabétique.