title: [Enhancement of cell growth by human interferons].
abstract: The effects of human interferons (HuIFN) on the human osteosarcoma cells were examined. HuIFN-alpha, -beta and -gamma enhanced dose-dependently the cell growth. There was no difference in the degree of the enhancement of the cell growth among HuIFN-alpha, -beta and -gamma. The higher the cell density was, the lower the degree of the enhancement of the cell growth. When HuIFN-gamma was neutralized with anti-HuIFN-gamma, the enhancement of cell growth was not found.
authors: Département de Microbiologie, Université Médicale de la Préfecture de Kyoto, Japan.
authors: N
authors: N
authors: Yamaguchi
authors: L J
authors: LJ
authors: Tong
authors: Y
authors: Y
authors: Yamamura
authors: G
authors: G
authors: Otsuka
authors: Y
authors: Y
authors: Tamura
authors: M
authors: M
authors: Kita
authors: J
authors: J
authors: Imanishi
mesh_terms: D000293:Adolescent; D002455:Cell Division / Q000187:drug effects; D005260:Female; D006801:Humans; D007370:Interferon Type I / Q000494:pharmacology*; D007371:Interferon-gamma / Q000494:pharmacology*; D012516:Osteosarcoma / Q000473:pathology; D013268:Stimulation, Chemical; D014407:Tumor Cells, Cultured / Q000187:drug effects
chemical_list: D007370:Interferon Type I; D007371:Interferon-gamma
vernacular_title: Accélération de la croissance cellulaire par les interférons humains.