title: [Long-term effects of cardiac pacing on natriuretic atrial peptide levels in patients with AV block].
abstract: In this work we intend to analyze the long term effects of the classic modes of definitive cardiac pacing (VVI and DDD) on the atrial natriuretic peptide levels. A priori hypothesis is: the AV asynchrony raises the hormonal level. The design is a cross-sectional study, and the setting is the pacemaker doctor's room of a tertiary hospital. In 24 patients (17 VVI and 7 DDD) the atrial natriuretic peptide was determined by RIA. A multiple regression model was fitted to analysis. The basic result is: when several factors were controlled (age, sex, hypertension, and cardiac failure story), the atrial natriuretic peptide levels are increased in the VVI group. In conclusion, the lack of AV synchrony induced the increase of atrial natriuretic levels. For an endocrine viewpoint the DDD is more physiological pacing as well.
authors: Servicios de Cardiología, Hospital de Alicante.
authors: J B
authors: JB
authors: Cabello
authors: P
authors: P
authors: Bordes
authors: M
authors: M
authors: Mauri
authors: M V
authors: MV
authors: Lozano
authors: A
authors: A
authors: Herrero
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D009320:Atrial Natriuretic Factor / Q000097:blood*; D005260:Female; D006327:Heart Block / Q000097:blood* / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial
chemical_list: D009320:Atrial Natriuretic Factor
vernacular_title: Efectos crónicos de la estimulación cardíaca sobre los niveles de hormona auricular natriurética en pacientes con bloqueo AV.