Characteristics of paroxysmal nocturnal hemoglobinuria in China. Clinical analysis of 476 cases.
476 cases of paroxysmal nocturnal hemoglobinuria (PNH) were analysed and compared with PNH patients in foreign countries and its classification was discussed. The clinical characteristics in Chinese PNH patients were: males were affected more; the age of onset was young; more common in north China; hemoglobinuria as an initial symptom was less common; thrombosis as a complication was relatively rare; the common causes of death were heart failure, infections and hemorrhage; and bone marrow picture might show mild dyshematopoiesis.
Le
X F
XF
Institute of Hematology, Chinese Academy of Medical Sciences, Tianjin.
Yang
T Y
TY
Yang
X Y
XY
Wang
X M
XM
D000293:Adolescent; D000328:Adult; D000368:Aged; D001856:Bone Marrow Examination; D002648:Child; D002681:China / Q000453:epidemiology; D005260:Female; D006457:Hemoglobinuria, Paroxysmal / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis