Trend analysis for repeated measures designs.
This paper outlines a method of analysis that is well-suited to repeated measures designs. This method uses polynomial functions of time to characterize an outcome variable measured at several distinct time points on the same subjects. Profiles for different treatment groups may be compared using the appropriate interaction terms in an analysis of variance table. The method is illustrated with data from two recent studies.
Holbert
D
D
Biostatistics/Epidemiology Research Program, East Carolina University, Greenville, NC 27858-4353.
Chenier
T C
TC
O'Brien
K F
KF
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