title: Oral focal mucinosis.
abstract: Oral focal mucinosis (OFM) is an uncommon clinicopathological entity which is considered to be the oral counterpart of cutaneous focal mucinosis and/or cutaneous myxoid cyst. It is comprised of a clinically elevated mass with a histological picture of localized areas of myxomatous connective tissue. The present study adds 15 new cases of OFM to the literature and analyzes their clinical, histological and histochemical features. Most of the lesions were located in the gingiva and alveolar mucosa. The nature of the lesion is unclear and it is suggested that the mucinous accumulation is the result of fibroblastic overproduction of hyaluronic acid.
authors: Department of Oral Pathology and Oral Medicine, School of Dental Medicine, Tel Aviv University, Israel.
authors: A
authors: A
authors: Buchner
authors: P W
authors: PW
authors: Merrell
authors: A S
authors: AS
authors: Leider
authors: L S
authors: LS
authors: Hansen
mesh_terms: D000293:Adolescent; D000328:Adult; D003094:Collagen / Q000737:chemistry; D003238:Connective Tissue / Q000737:chemistry / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005347:Fibroblasts / Q000473:pathology; D005350:Fibroma / Q000473:pathology; D005882:Gingival Diseases / Q000378:metabolism / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000378:metabolism / Q000473:pathology*; D009061:Mouth Mucosa / Q000737:chemistry / Q000473:pathology; D009062:Mouth Neoplasms / Q000473:pathology; D009077:Mucins / Q000737:chemistry*; D009232:Myxoma / Q000473:pathology; D010509:Periodontal Cyst / Q000473:pathology
chemical_list: D009077:Mucins; D003094:Collagen