Viral battery testing in nonhuman primate colony management.
Good colony management is associated with monitoring of animals for infectious agents. Of major current concern are B virus and simian AIDS (SAIDS) viruses. However, other viral agents frequently cause serious disease outbreaks which can be avoided if their presence is detected sufficiently early. The recent development of a rapid, sensitive and specific diagnostic test system, i.e., the dot immunobinding assay (DIA) permits the monitoring of a colony for many of the viruses that pose problems. By employing battery type testing using a panel of appropriate viral antigens, investigators are able to detect the increased presence of viral agents of concern and take necessary measures to prevent extension of the problem.
Kalter
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SS
WHO Collaborating Center for Reference and Research in Simian Viruses, San Antonio, TX 78229.
Heberling
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RL
D000822:Animal Husbandry; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D000956:Antigens, Viral; D002522:Chlorocebus aethiops / Q000276:immunology; D006071:Gorilla gorilla / Q000276:immunology; D015151:Immunoblotting / Q000379:methods / Q000662:veterinary*; D008251:Macaca / Q000276:immunology; D002679:Pan troglodytes / Q000276:immunology
D000914:Antibodies, Viral; D000956:Antigens, Viral