[Brain-gut axis: implications on the genesis of peptic ulcer].
Clinical and laboratory evidence indicate that the brain exerts mayor control on the gastro-intestinal tract. Specific brain loci and circuits send efferent viscerotropic projections to the gut have been summarized. A variety of aminergic and peptidergic neurotransmitters have been shown specially and their function on gastric acid secretion and implications for ulcer disease. These findings suggest that ulcer disease may represents a brain-driven event, which may be the result of a neurochemical imbalance within the brain.
Rojas Bueno
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Hospital Angel Larralde, Universidad de Carabobo.
D001921:Brain / Q000502:physiology*; D004068:Digestive System Physiological Phenomena; D005744:Gastric Acid / Q000378:metabolism; D006801:Humans; D009479:Neuropeptides / Q000502:physiology; D010437:Peptic Ulcer / Q000209:etiology*
D009479:Neuropeptides
Eje cerebro-gastrointestinal: implicaciones en la génesis de la úlcera péptica.