Atrial natriuretic factor in idiopathic minimal-lesion nephrotic syndrome.
The plasma levels of atrial natriuretic factor (ANF) were measured both during relapse and remission in 8 patients with idiopathic, minimal-lesion nephrotic syndrome. The plasma levels of ANF were significantly higher in the patients during relapse (53.3 +/- 21.2 pg/ml, mean +/- SEM) as compared to the values observed in the same patients during remission (19.4 +/- 4.1 pg/ml; p less than 0.05). This moderate increase in ANF is not likely to be explained by hypervolemia and is associated with sodium and water retention rather than natriuresis and diuresis.
Garin
E H
EH
Department of Pediatrics, University of South Florida, Tampa.
Paul
R V
RV
D009320:Atrial Natriuretic Factor / Q000097:blood*; D002648:Child; D004487:Edema / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D009402:Nephrosis, Lipoid / Q000097:blood* / Q000150:complications; D011863:Radioimmunoassay; D012008:Recurrence
D009320:Atrial Natriuretic Factor