[Gene cloning of human dopaminergic D3 receptor and identification of its chromosome].
The coding region of the human dopaminergic D3 receptor gene was cloned and sequenced. The deduced amino acid sequence displays a global homology of 78% with rat D3 receptor with a deletion of 46 residues within the third intracytoplasmic loop. Southern analysis assigned the human gene to chromosome 3.
Giros
B
B
Unité de Neurobiologie et Pharmacologie (U.n. 109) de l'I.N.S.E.R.M., Centre Paul-Broca, Paris.
Martres
M P
MP
Sokoloff
P
P
Schwartz
J C
JC
D000595:Amino Acid Sequence / Q000235:genetics; D000818:Animals; D001483:Base Sequence / Q000235:genetics; D002893:Chromosomes, Human, Pair 3 / Q000737:chemistry*; D003001:Cloning, Molecular; D006801:Humans; D051381:Rats; D011954:Receptors, Dopamine / Q000235:genetics*; D017448:Receptors, Dopamine D2; D050637:Receptors, Dopamine D3
C493593:DRD3 protein, human; C493595:Drd3 protein, rat; D011954:Receptors, Dopamine; D017448:Receptors, Dopamine D2; D050637:Receptors, Dopamine D3
Clonage du gène du récepteur dopaminergique D3 humain et identification de son chromosome.