Targeting of transgene expression to monocytes by cytochrome b heavy chain gene 5'-flanking sequences induces histiocytic malignancies.
Skalnik
D G
DG
Division of Hematology/Oncology, Children's Hospital, Boston, MA.
Dorfman
D M
DM
Perkins
A S
AS
Jenkins
N A
NA
Copeland
N G
NG
Orkin
S H
SH
D000818:Animals; D000957:Antigens, Viral, Tumor / Q000235:genetics; D003573:Cytochrome b Group / Q000235:genetics*; D004273:DNA, Neoplasm / Q000235:genetics; D005260:Female; D005809:Genes, Regulator; D006410:Hematopoiesis / Q000235:genetics; D015620:Histiocytic Disorders, Malignant / Q000235:genetics* / Q000276:immunology / Q000378:metabolism; D006801:Humans; D051379:Mice; D008815:Mice, Inbred Strains; D008822:Mice, Transgenic; D009000:Monocytes / Q000378:metabolism*; D011247:Pregnancy; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism
D000957:Antigens, Viral, Tumor; D003573:Cytochrome b Group; D004273:DNA, Neoplasm; D012333:RNA, Messenger