Uterine large granular lymphocytes: a possible role in embryonic implantation?
Leukocytes in endometrium and decidua are phenotypically and morphologically similar to granulated lymphocytes at other mucosal surfaces. Although their exact functions are not known, we suggest they may have a role in the control of implantation and the transformation of the uterine vasculature by trophoblast on which the blood supply to the fetoplacental unit depends.
King
A
A
Cambridge University Department of Pathology, England.
Loke
Y W
YW
D000818:Animals; D000945:Antigens, Differentiation, T-Lymphocyte / Q000032:analysis; D017252:CD3 Complex; D010064:Embryo Implantation / Q000502:physiology; D004622:Embryo, Mammalian / Q000276:immunology*; D005260:Female; D006801:Humans; D007694:Killer Cells, Natural / Q000502:physiology; D008214:Lymphocytes / Q000502:physiology*; D011247:Pregnancy; D011948:Receptors, Antigen, T-Cell / Q000032:analysis; D014599:Uterus / Q000276:immunology*
D000945:Antigens, Differentiation, T-Lymphocyte; D017252:CD3 Complex; D011948:Receptors, Antigen, T-Cell