Prevalence of primary Sjögren's syndrome in patients with multiple sclerosis.
Sixty-four consecutive patients with clinically or laboratory-supported definite multiple sclerosis (MS) were evaluated prospectively for evidence of primary Sjögren's syndrome (SS). This diagnosis was established when a patient had objective keratoconjunctivitis sicca, xerostomia, or both together with positive labial salivary gland biopsy. We found 2 patients (3.1%) with clinical evidence of primary SS. Whether this association is fortuitous or whether there is pathogenetic linkage between MS and primary SS remains to be established.
Miró
J
J
Service of Neurology, National Hospital, Marqués de Valdecilla, University of Cantabria, Santander, Spain.
Peña-Sagredo
J L
JL
Berciano
J
J
Insúa
S
S
Leno
C
C
Velarde
R
R
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications*; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis