[Calcium dobesilate in the treatment of primary venous insufficiency of the lower limbs. A controlled clinical study].
Fourty patients with lower limb chronic venous insufficiency entered a randomised placebo controlled study with calcium dobesilate for one month. Clinical symptoms and plethysmographic parameters were evaluated before and after therapy in all patients. In the group of patients treated with calcium dobesilate we observed an improvement of clinical and instrumental parameters; no changes were found in the placebo group. We observed good tolerance to the drug and no side effects required withdrawal of treatment.
Pecchi
S
S
Università degli Studi di Siena, Istituto di Patologia Speciale Medica e Metodologia Clinica.
De Franco
V
V
Damiani
P
P
Guerrini
M
M
Di Perri
T
T
D000368:Aged; D001557:Benzenesulfonates / Q000627:therapeutic use*; D002123:Calcium Dobesilate / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016032:Randomized Controlled Trials as Topic; D014689:Venous Insufficiency / Q000188:drug therapy*
D001557:Benzenesulfonates; D002123:Calcium Dobesilate
Il dobesilato di calcio nel trattamento dell'insufficienza venosa primitiva degli arti inferiori. Studio clinico controllato.