title: [A simple method of synthesis of 3-acetyl-5-(D-arabino-tetrahydroxybutyl)-2-methylpyrrole].
abstract: The reaction of D-fructose with ammonium carbonate and 2,4-pentanedione leads in one step to 3-acetyl-5-(D-arabino-tetrahydroxybutyl)-2-methylpyrrole. This compound has been found to display anticancer activity.
authors: Zakładu Chemii Organicznej Akademii Medycznej, Białymstoku.
authors: A
authors: A
authors: Rózański
authors: K
authors: K
authors: Bielawski
authors: J
authors: J
authors: Bołtryk
authors: D
authors: D
authors: Bartulewicz
mesh_terms: D000903:Antibiotics, Antineoplastic / Q000138:chemical synthesis* / Q000737:chemistry; D002254:Carbonates / Q000494:pharmacology; D002626:Chemistry, Pharmaceutical; D005632:Fructose / Q000494:pharmacology; D007202:Indicators and Reagents / Q000494:pharmacology; D008722:Methods; D010422:Pentanones / Q000494:pharmacology; D014255:Trichothecenes / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D000903:Antibiotics, Antineoplastic; D002254:Carbonates; D007202:Indicators and Reagents; D010422:Pentanones; D014255:Trichothecenes; D005632:Fructose; C008790:acetylacetone; C032865:VER I; C040502:ammonium carbonate
vernacular_title: Prosta metoda syntezy 3-acetylo-5-(D-arabino-tetrahydroksybutylo)-2-metylopirolu.