Manifestations and outcome of treatment of thyrotoxicosis: a clinical study.
We studied a series of 89 consecutive patients who presented with thyrotoxicosis at a medical unit. Clinical parameters and laboratory abnormalities were recorded. Treatment was initiated and response in terms of side-effects, clinical and laboratory remissions were monitored. The frequency of the various clinical manifestations, cardiovascular and neurological complications were documented. Laboratory data on electrolytes, haematological changes and thyroid antibodies were noted. The treatment outcome revealed a relapse of 37.7% in patients with 6 months of treatment (90% occurred within the first year). We also noted that 6.7% of patients developed skin reaction. A treatment default rate of 30% was noted.
Tan
C E
CE
Department of Medicine I, Singapore General Hospital.
Wang
K W
KW
Chew
L S
LS
Rajasoorya
C
C
Lim
H S
HS
D000293:Adolescent; D000328:Adult; D000368:Aged; D002231:Carbimazole / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012846:Singapore; D013971:Thyrotoxicosis / Q000188:drug therapy* / Q000503:physiopathology
D002231:Carbimazole