Roles of G proteins and G protein subunits in signal transduction.
General features of signal transduction by G proteins are described. Recent results on roles of beta gamma dimers, kinetic properties of Gi alpha subunits, structural diversity of Go alpha subunits and possible functions of the Go protein as a stimulator of phospholipase C activity are discussed.
Iyengar
R
R
Department of Pharmacology, Mount Sinai School of Medicine, New York, NY 10029.
Birnbaumer
L
L
D000595:Amino Acid Sequence; D000818:Animals; D001704:Biopolymers; D019204:GTP-Binding Proteins / Q000502:physiology*; D008969:Molecular Sequence Data; D015398:Signal Transduction / Q000502:physiology*; D014982:Xenopus laevis
D001704:Biopolymers; D019204:GTP-Binding Proteins