title: Zymodemes of Entamoeba histolytica in Dhaka, Bangladesh.
abstract: Stool samples containing Entamoeba histolytica were obtained from two sources: an urban hospital and an urban slum. Using the enzyme patterns of three enzymes (E.C.2.7.1.1 hexokinase, E.C.5.3.1.9 glucose phosphate isomerase and E.C.2.7.5.1 phosphoglucomutase) stained after cellulose acetate electrophoresis, four zymodemes (I, II, XIV and XVI) were identified in 71 isolates. Zymodemes considered to be pathogenic (II and XIV) were identified from 31 of 34 isolates from the urban hospital, and these zymodemes were strongly associated with dysentery and trophozoites containing ingested red blood corpuscles. Blood visible to the naked eye was more commonly seen in stools from which zymodeme XIV was isolated than in those containing zymodeme II (P less than 0.001). Zymodemes considered to be non-pathogenic (I and XVI) were identified in 34 of 37 isolates from slum dwellers and were not associated with blood in the stools.
authors: International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
authors: R
authors: R
authors: Haque
authors: A
authors: A
authors: Hall
authors: S
authors: S
authors: Tzipori
mesh_terms: D000818:Animals; D001459:Bangladesh; D004748:Entamoeba histolytica / Q000145:classification / Q000201:enzymology*; D004906:Erythrocyte Count; D005956:Glucose-6-Phosphate Isomerase / Q000032:analysis; D006593:Hexokinase / Q000032:analysis; D006801:Humans; D009780:Occult Blood; D010733:Phosphoglucomutase / Q000032:analysis
chemical_list: D006593:Hexokinase; D005956:Glucose-6-Phosphate Isomerase; D010733:Phosphoglucomutase