[Diagnostic differentiation between precocious puberty and premature thelarche using ultrasonography and the stimulated LH/FSH quotient].
True precocious puberty represents a serious developmental disorder necessitating immediate therapeutic measures, whereas premature thelarche is a harmless variation from the norm. For the differential diagnosis the ultrasonographic evaluation of the internal genitalia is of value. Girls with precocious puberty reveal a statistically significantly greater uterus length and volume as well as ovarian size. The stimulated LH/FSH quotient allows verification of the diagnosis. This value is found always to be greater than 1 in precocious puberty and always less than 1 in premature thelarche.
Pelzer
V
V
Universitäts-Frauenklinik Düsseldorf.
Von Ditfurth
M
M
Wendel
U
U
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood*; D007987:Gonadotropin-Releasing Hormone; D006801:Humans; D007223:Infant; D007986:Luteinizing Hormone / Q000097:blood*; D010053:Ovary / Q000000981:diagnostic imaging; D011629:Puberty, Precocious / Q000097:blood / Q000000981:diagnostic imaging*; D012741:Sexual Maturation / Q000502:physiology*; D014463:Ultrasonography; D014599:Uterus / Q000000981:diagnostic imaging
D007987:Gonadotropin-Releasing Hormone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
Differentialdiagnostische Abgrenzung der Pubertas praecox gegen die prämature Thelarche mit Hilfe der Ultrasonographie und dem stimulierten LH/FSH-Quotienten.