Immunocytochemical detection of protein p38 in human dental pulp.
The occurrence and distribution of protein p38 (synaptophysin) were investigated by immunofluorescence. Immunoreactivity for protein p38-like antigen was detected within axons of radicular nerve trunks entering the tooth and within nerve terminals close to blood vessels. Immunoreactive structures were also observed in the para-odontoblastic region. It is proposed that protein p38, translocated within small synaptic vesicles from neuronal perikarya along the axons, may be a reliable marker for detection of nerve endings in human tooth.
Casasco
A
A
Istituto di Istologia ed Embriologia, Università di Pavia, Italy.
Calligaro
A
A
Casasco
M
M
Menghini
P
P
Marchetti
C
C
Poggi
P
P
Springall
D R
DR
Polak
J M
JM
D001369:Axons / Q000737:chemistry; D003782:Dental Pulp / Q000737:chemistry* / Q000294:innervation; D006801:Humans; D007150:Immunohistochemistry; D008565:Membrane Proteins / Q000032:analysis*; D009411:Nerve Endings / Q000737:chemistry; D009412:Nerve Fibers / Q000737:chemistry; D009419:Nerve Tissue Proteins / Q000032:analysis*; D016708:Synaptophysin
D008565:Membrane Proteins; D009419:Nerve Tissue Proteins; D016708:Synaptophysin