[In vitro activity of mupirocin, a new topical agent against Staphylococcus aureus].
The in vitro activity of mupirocin (pseudomonic acid), a new topic antibiotic, was evaluated against 70 S. aureus strains from health care staff of our hospital. The activity of the antibiotic was excellent, with a HIC90 of 0.25 mg/l. Mupirocin activity was higher than that of cloxacillin and bacitracin and similar to that neomycin.
Rosales Rodríguez
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Servicio de Medicina Preventiva y Salud Pública, Hospital Juan Canalejo, La Coruña.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001414:Bacitracin / Q000494:pharmacology; D003023:Cloxacillin / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D004352:Drug Resistance, Microbial; D005227:Fatty Acids / Q000494:pharmacology; D006801:Humans; D016712:Mupirocin; D009355:Neomycin / Q000494:pharmacology; D012867:Skin / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification
D000900:Anti-Bacterial Agents; D005227:Fatty Acids; D001414:Bacitracin; D016712:Mupirocin; D009355:Neomycin; D003023:Cloxacillin
Actividad in vitro de mupirocina, un nuevo agente tópico frente a Staphylococcus aureus.