title: Recent studies on the molecular biology and biochemistry of CO2 fixation in phototrophic bacteria.
abstract: Rhodobacter sphaeroides was found to contain two clusters of chromosomally encoded CO2 fixation structural genes. Recent studies indicate that genes within each cluster are cotranscribed, suggesting that there is a single long transcript for each cluster. All of the genes have been sequenced, homologies noted, specific mutations obtained, and interesting upstream regulatory sequences found. Site-directed mutagenesis studies of the Anacystis rbcS has begun to provide information relative to RubisCO structure and function. In addition, RubisCO-negative strains of photosynthetic bacteria have been constructed to screen for altered RubisCO sequences.
authors: Department of Microbiology, Ohio State University, Columbus 43210.
authors: F R
authors: FR
authors: Tabita
authors: J L
authors: JL
authors: Gibson
authors: D L
authors: DL
authors: Falcone
authors: B G
authors: BG
authors: Lee
authors: J H
authors: JH
authors: Chen
mesh_terms: D001483:Base Sequence; D002245:Carbon Dioxide / Q000378:metabolism*; D004798:Enzymes / Q000235:genetics; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial; D016297:Mutagenesis, Site-Directed; D012242:Rhodobacter sphaeroides / Q000235:genetics*; D013329:Structure-Activity Relationship
chemical_list: D004798:Enzymes; D002245:Carbon Dioxide