title: [Blood coagulation changes in systemic lupus erythematosus].
abstract: Changes of blood coagulation in 32 cases of SLE were investigated. Abnormalities frequently found were elevation of blood fibrinogen, FDP, V111R: Ag levels, prolonged or shortened KPTT time, and depressed AT-III value. Half of the patients with SLE showed laboratory changes compatible with the diagnostic criteria of DIC, but acute DIC was encountered clinically only in 2 cases hypercoagulation state or hypercoagulation with lower fibrinolysis, however were frequently seen. Lupus anticoagulant were detected in 6 patients and deep vein thrombosis of lower extremity in 1 patient. Examination of blood coagulation in patients with SLE was, therefore, of clinical importance.
authors: Affiliated Tongji Hospital, Tongji Medical University.
authors: W L
authors: WL
authors: Liu
authors: H Z
authors: HZ
authors: Xiu
authors: H Y
authors: HY
authors: Sun
mesh_terms: D000328:Adult; D001779:Blood Coagulation Factors / Q000032:analysis* / Q000276:immunology; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D016682:Lupus Coagulation Inhibitor; D008180:Lupus Erythematosus, Systemic / Q000097:blood* / Q000150:complications; D008297:Male; D008875:Middle Aged; D014841:von Willebrand Factor / Q000032:analysis
chemical_list: D001779:Blood Coagulation Factors; D005338:Fibrin Fibrinogen Degradation Products; D016682:Lupus Coagulation Inhibitor; D014841:von Willebrand Factor; D005340:Fibrinogen