Successful fluvoxamine treatment of a case of refractory obsessive-compulsive disorder.
Fluvoxamine, a potent and selective serotonin uptake inhibitor, effectively reduced compulsive handwashing and other rituals in a patient previously refractory to behaviour therapy, clomipramine, MAO inhibitors and other pharmacotherapy. Treatment effect was delayed but broadly patholytic, reducing anxiety and depression scores as well as ratings of obsessiveness.
Solyom
L
L
University Hospital, University of British Columbia, Vancouver.
Solyom
C A
CA
D000328:Adult; D000928:Antidepressive Agents; D005260:Female; D016666:Fluvoxamine; D006760:Hospitalization; D006801:Humans; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy* / Q000523:psychology; D010091:Oximes / Q000627:therapeutic use*; D010556:Personality Tests
D000928:Antidepressive Agents; D010091:Oximes; D016666:Fluvoxamine