An immunophenotypic study of lichen nitidus.
Skin biopsies from three patients with lichen nitidus were studied using a battery of monoclonal antibodies against cells in the dermal infiltrate. In each case the findings were identical with a marked excess of CD4+ cells over CD8+ cells and the presence of large numbers of CD1+ cells. These results are very similar to those seen in lichen planus reinforcing the association between these two conditions.
Wright
A L
AL
Department of Dermatology, Royal Hallamshire Hospital, Sheffield, UK.
McVittie
E
E
Hunter
J A
JA
D000911:Antibodies, Monoclonal / Q000276:immunology; D015703:Antigens, CD / Q000032:analysis; D006801:Humans; D008010:Lichen Planus / Q000473:pathology*; D012867:Skin / Q000473:pathology*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
D000911:Antibodies, Monoclonal; D015703:Antigens, CD