Contribution of pregnan steroid Althesin to the pathophysiology of epilepsy.
The original study with Althesin in the development of epilepsy was carried out in nine patients. EEG and SEEG records show that sensitivity to Althesin, which is a mixture of pregnandiol and pregnan acetate, precursors of sexual hormones, raises in the direction to the oldest brain formations. A physiological substance in provoking epilepsy was discovered.
Nádvorník
P
P
Research Institute of Higher Nervous Activity, Palacký University, Olomouc, Czechoslovakia.
Kolarík
J
J
Drlicková
V
V
D000530:Alfaxalone Alfadolone Mixture / Q000494:pharmacology*; D004569:Electroencephalography / Q000187:drug effects*; D004827:Epilepsy / Q000503:physiopathology*; D006801:Humans
D000530:Alfaxalone Alfadolone Mixture