[Thiamine stability in parenteral nutrition].
In the present work we have studied the stability of thiamine by HPLC in parenteral nutritions provided with or without lipids. As source of nitrogen we have used Freamine 8.5%. Thiamine came from the multi-vitamin complex Pancebrin. The results of this study show that this vitamin is not stable for more than 24 h, even if parenteral nutritions are kept at 4 degrees C, except for solutions that do not contain lipids and are kept at 4 degrees C. Light does not influence the degradation rate of thiamine.
Montero
C G
CG
Servicio de Farmacia, Hospital Universitario Virgen del Rocío, Sevilla.
Vílchez
T
T
Cantabrana
F
F
Atienza
M
M
D004355:Drug Stability; D010289:Parenteral Nutrition, Total; D013831:Thiamine / Q000737:chemistry*
D013831:Thiamine
Estabilidad de tiamina en nutrición parenteral.