title: Cogan's syndrome.
abstract: Cogan's syndrome is a rare systemic autoimmune disease with preeminent ophthalmological and vestibulocochlear manifestations. Untreated, the disease usually results in profound deafness; eye involvement is usually self-remitting. Ten to twenty percent of patients either develop serious aortic valve disease or vasculitis or both. When given early, immunosuppressive therapy has been shown to be effective in treating all aspects of the disease. Thus, early disease recognition is of great significance. We present a patient with Cogan's syndrome and briefly discuss therapeutic implications.
authors: Department of Neurology, University of Bern, Switzerland.
authors: E
authors: E
authors: Wilder-Smith
authors: U
authors: U
authors: Roelcke
mesh_terms: D000328:Adult; D001327:Autoimmune Diseases / Q000188:drug therapy / Q000503:physiopathology*; D003638:Deafness / Q000276:immunology; D005128:Eye Diseases / Q000188:drug therapy / Q000276:immunology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D013577:Syndrome; D015837:Vestibular Diseases / Q000188:drug therapy / Q000276:immunology* / Q000503:physiopathology
chemical_list: D007166:Immunosuppressive Agents