[Anti-GFAP antibodies in the cerebrospinal fluid of patients with multiple sclerosis and other neurologic diseases].
The antibodies against glial fibrillary acidic protein (GFAP) in the CSF of patients with multiple sclerosis and other neurological diseases were determined. It was shown that the binding activity of CSF IgG with GFAP was higher in patients with MS and other organic neurological diseases as compared to control group (neurotics). The results support the idea, that in SM there is a general immune dysregulation, leading to production of a variety of autoantibodies against different antigens, including the presently shown GFAP.
Górny
M
M
Katedry i Zakładu Patomorfologii Klinicznej AM w Poznanin.
Losy
J
J
Wender
M
M
D001323:Autoantibodies / Q000134:cerebrospinal fluid*; D001327:Autoimmune Diseases / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000276:immunology*; D003937:Diagnosis, Differential; D004827:Epilepsy / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000276:immunology*; D005904:Glial Fibrillary Acidic Protein / Q000134:cerebrospinal fluid / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid*; D008590:Meningoencephalitis / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000276:immunology*; D009103:Multiple Sclerosis / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000276:immunology*; D012585:Sciatica / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000276:immunology*
D001323:Autoantibodies; D005904:Glial Fibrillary Acidic Protein; D007074:Immunoglobulin G
Przeciwciała przeciw kwaśnemu białku włókienkowemu gleju (GFAP) w płynie mózgowo-rdzeniowym chorych na stwardnienie rozsiane i inne choroby neurologiczne.