title: Plasma atrial natriuretic peptide after the Fontan procedure and total cavopulmonary connexion.
abstract: Plasma atrial natriuretic peptide was measured in 10 children undergoing the Fontan procedure and 3 children undergoing total cavopulmonary connexion. There was no significant difference in pre-operative plasma levels, but post-operative levels were significantly higher 48 hours after cardiopulmonary bypass in the Fontan group. There was no significant difference in plasma arginine vasopressin levels either pre- or post-operatively. Post-operative pleural effusions occurred in only 2 of the 10 patients undergoing the Fontan procedure, but were present in all 3 of those undergoing total cavopulmonary connexion. The release of atrial natriuretic peptide is an appropriate homeostatic response to volume loading and the impairment of this response in the early post-operative period may be of clinical importance.
authors: Brompton Hospital, London, U.K.
authors: M
authors: M
authors: Burch
authors: E A
authors: EA
authors: Shinebourne
authors: M L
authors: ML
authors: Rigby
authors: N
authors: N
authors: Carter
authors: S
authors: S
authors: Jeffery
authors: P
authors: P
authors: Stanley
authors: A
authors: A
authors: Smith
mesh_terms: D001127:Arginine Vasopressin / Q000097:blood; D009320:Atrial Natriuretic Factor / Q000097:blood*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D002315:Cardiopulmonary Bypass / Q000009:adverse effects; D002648:Child; D005260:Female; D006325:Heart Atria / Q000378:metabolism; D006801:Humans; D007223:Infant; D008297:Male; D011651:Pulmonary Artery / Q000601:surgery
chemical_list: D001127:Arginine Vasopressin; D009320:Atrial Natriuretic Factor