[Evaluation of lymphocytoxic antibody specificity in systemic lupus erythematosus: correlation with the clinical activity of the disease].
Forty two sera of 35 patients with systemic lupus erythematosus with or without clinically active disease were evaluated. The lymphocytotoxic complement dependent antibodies were detected in 66.66% of patients and were not related to class I of principal histocompatibility antigens or therapeutical use of corticosteroids.
Gauditano
G
G
Laboratório de Investigação em Reumatologia, Hospital das Clínicas da Faculdade de Medicina, Universidade, São Paulo FMUSP.
Oliveira
D de P
Dde P
Yoshinari
N H
NH
Cossermelli
W
W
D000918:Antibody Specificity / Q000276:immunology*; D000961:Antilymphocyte Serum / Q000276:immunology*; D003601:Cytotoxicity Tests, Immunologic; D005260:Female; D015395:Histocompatibility Antigens Class I / Q000032:analysis* / Q000276:immunology; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy / Q000276:immunology*; D008297:Male; D011241:Prednisone / Q000008:administration & dosage
D000961:Antilymphocyte Serum; D015395:Histocompatibility Antigens Class I; D011241:Prednisone
Avaliação da especificidade dos anticorpos linfocitotóxicos em lúpus eritematoso sistêmico: correlação com atividade clínica de doença.