[Dementia symptoms in Down's syndrome in a residentially treated group of mentally handicapped].
In a controlled retrospective study of 27 Down patients the occurrence of the neuropathological signs of Alzheimer's disease was investigated. The patients were divided into two groups: group I with neuropathologically proven Alzheimer and group II without Alzheimer's disease. All patients of group I had been older than 54 years at death, while all patients of group II were younger. All patients of group I suffered from severe dementia, none of group II did. The early clinical symptoms, changes in social competence and EEG alterations were combined in a dementia detection method suitable for mentally deficient patients.
Visser
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FE
's Heeren Loo-Lozenoord, Ermelo.
Kuilman
M
M
D000203:Activities of Daily Living; D000368:Aged; D000544:Alzheimer Disease / Q000150:complications* / Q000175:diagnosis; D004314:Down Syndrome / Q000150:complications*; D004569:Electroencephalography; D004827:Epilepsy / Q000150:complications; D005242:Fecal Incontinence / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012737:Sex Factors; D014549:Urinary Incontinence / Q000150:complications
Het vóórkomen van dementiële beelden bij het syndroom van Down in een residentieel verzorgde groep zwakzinnigen.