[Studies on blood galactokinase of patients with presenile and senile cataracts].
Whole blood galactokinase (GK) activities were determined in 278 individuals including 77 patients with senile cataracts, 60 with presenile cataracts and 141 normal controls. No significant difference was found among the GK levels of the three groups. The frequency of GK heterozygocity in the presenile cataract group, however, was significantly higher than that in the normal control group (P less than 0.01), suggesting that even a partial decrease in GK activity might facilitate cataract formation in relatively early stages of life. The intake of milk and its products should be limited, both in GK homo- and heterozygotes.
Xu
G
G
PUMC Hospital, Beijing.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002386:Cataract / Q000201:enzymology* / Q000235:genetics; D005260:Female; D005686:Galactokinase / Q000097:blood*; D006579:Heterozygote; D006801:Humans; D008297:Male; D008875:Middle Aged
D005686:Galactokinase