The role of the NMDA receptor in the development of the frog visual system.
The importance of patterned retinal activity in visual system development has been recognized since Hubel and Wiesels early experiments (1963). The NMDA receptor is one cellular mechanism which can recognize patterned retinal activity and convey an intracellular message of that activity. It will now be of considerable interest to elucidate the cellular events involved in synapse stabilization subsequent to NMDA receptor activation.
Cline
H T
HT
Department of Biology, Yale University, New Haven, CT 06511.
Debski
E A
EA
Constantine-Paton
M
M
D000818:Animals; D001369:Axons / Q000502:physiology; D002118:Calcium / Q000378:metabolism; D011894:Rana pipiens; D016194:Receptors, N-Methyl-D-Aspartate / Q000502:physiology*; D012160:Retina / Q000254:growth & development / Q000502:physiology; D013477:Superior Colliculi / Q000254:growth & development / Q000502:physiology; D013569:Synapses / Q000502:physiology; D014795:Visual Pathways / Q000254:growth & development / Q000502:physiology*
D016194:Receptors, N-Methyl-D-Aspartate; D002118:Calcium