Expression of complement C3b/C4b receptors (CR1) on erythrocytes from patients with myasthenia gravis.
The complement C3b/C4b receptor (CR1) expression on erythrocytes (E) (ECR1) from patients with myasthenia gravis (MG) and from blood donors was measured using haemadsorption and indirect hemagglutination techniques. The ECR1 expression in patients with MG appeared to be normal. This was also true for the subgroup of MG patients with additional autoimmune diseases. No correlation between ECR1 expression and severity of myasthenic symptoms was demonstrated.
Vedeler
C A
CA
Department of Neurology, University of Bergen, Norway.
Gilhus
N E
NE
Matre
R
R
D000293:Adolescent; D000328:Adult; D000368:Aged; D001327:Autoimmune Diseases / Q000276:immunology; D002352:Carrier Proteins / Q000276:immunology*; D003169:Complement Inactivator Proteins; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D006023:Glycoproteins; D006382:Hemadsorption / Q000502:physiology; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D008297:Male; D008875:Middle Aged; D009157:Myasthenia Gravis / Q000175:diagnosis / Q000276:immunology*; D011951:Receptors, Complement / Q000276:immunology*; D017463:Receptors, Complement 3b
D002352:Carrier Proteins; D003169:Complement Inactivator Proteins; D006023:Glycoproteins; D011951:Receptors, Complement; D017463:Receptors, Complement 3b