title: Ultrasound diagnosis and screening of fetal cystic fibrosis.
abstract: By ultrasound examination of high risk pregnancies for cystic fibrosis in some cases echogenic areas and dilated bowels could be demonstrated. These signs could be detected in 75% of those cases where biochemical assay of the amniotic fluid proved the fetus to be affected with cystic fibrosis. Having got these results authors started to look for these signs during the screening of normal pregnancies. Out of 22 thousand screened pregnancies 28 amniocenteses have been performed because of the ultrasound finding and in 18 cases the low microvillar enzyme activity also predicted cystic fibrosis.
authors: Department of Obstetrics and Gynaecology, University Medical School of Debrecen, Hungary.
authors: O
authors: O
authors: Török
authors: Z
authors: Z
authors: Tóth
authors: M
authors: M
authors: Szabó
authors: Z
authors: Z
authors: Papp
mesh_terms: D000653:Amniotic Fluid / Q000201:enzymology; D003550:Cystic Fibrosis / Q000000981:diagnostic imaging* / Q000201:enzymology / Q000517:prevention & control; D004064:Digestive System / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008403:Mass Screening; D011247:Pregnancy; D016216:Ultrasonography, Prenatal