title: [Infection induced in wild rodents Dasyprocta leporina (Rodentia: Dasyproctidae), with larval eggs of Lagochilascaris minor (Nematoda: Ascarididae)].
abstract: Specimens of Dasyprocta leporina (Linnaeus, 1758) were raised out their natural environment. At three to four months of age they were orally inoculated with Lagochilascaris minor (Leiper, 1909) eggs obtained from a native patient. The eggs were incubated for more than 80 days so that it was possible to obtain, by mechanical compression, larvae that could be maintained alive in liquid medium for 48 hours or more. The animals were sacrificed 14-46 days after infection and tangled larva in inflammatory nodules were found in skeletal muscle without foreign body reaction, abscess formation or calcification. The development of the nodules did not seem to affect the hosts. The larvae obtained were similar to those described by SPRENT as the third stage of these helminths. When white mice were inoculated with similar material it was not possible to recuperate larva from their tissues nor were nodules found. Based on these results it is postulated that the helminth does not present a pulmonary cycle and that its development requires an intermediary host.
authors: Departamento de Parasitología y Microbiología, Escuela de Medicina, Universidad de Oriente, Ciudad Bolívar, Venezuela.
authors: G S
authors: GS
authors: Volcán
authors: C E
authors: CE
authors: Medrano
mesh_terms: D000818:Animals; D001197:Ascaridia / Q000502:physiology; D001198:Ascaridiasis / Q000469:parasitology* / Q000473:pathology; D006790:Host-Parasite Interactions; D009132:Muscles / Q000469:parasitology*; D012377:Rodentia
vernacular_title: Infección inducida en el roedor selvático Dasyprocta leporina (Rodentia: Dasyproctidae), con huevos larvados de Lagochilascaris minor (Nematoda: Ascarididae).