[Response of estrogen and progesterone receptors to treatment with large doses of progestogen (depo-provera) in endometrial cancer].
Investigations of estrogen and progesterone receptors content in 28 women with endometrial cancer in the cancer tissue. During treatment with large doses of MPA (Depo-Provera) a significant decrease of progesterone receptors was observed.
Thurzó
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Universitäts-Frauenklinik Albert-Szent Györgyi, Szeged.
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000473:pathology; D000970:Antineoplastic Agents; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004717:Endometrium / Q000187:drug effects / Q000473:pathology; D005260:Female; D006801:Humans; D008525:Medroxyprogesterone / Q000008:administration & dosage / Q000031:analogs & derivatives*; D017258:Medroxyprogesterone Acetate; D009376:Neoplasms, Hormone-Dependent / Q000188:drug therapy* / Q000473:pathology; D011960:Receptors, Estrogen / Q000187:drug effects*; D011980:Receptors, Progesterone / Q000187:drug effects*; D014594:Uterine Neoplasms / Q000188:drug therapy* / Q000473:pathology
D000970:Antineoplastic Agents; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D017258:Medroxyprogesterone Acetate; D008525:Medroxyprogesterone
Die Reaktion der Estrogen- und Progesteron-Rezeptoren des Endometriumkarzinoms auf die Behandlung mit grossen Dosen Progestogen (Depo-Provera).