Acute toxicity of anti-CD3 monoclonal antibody in mice: a model for OKT3 first dose reactions.
Alegre
M
M
Université Libre de Bruxelles, Belgium.
Depierreux
M
M
Florquin
S
S
Najdovski
T
T
Vandenabeele
P
P
Abramowicz
D
D
Leo
O
O
Deschodt-Lanckman
M
M
Goldman
M
M
D000818:Animals; D000911:Antibodies, Monoclonal / Q000009:adverse effects* / Q000633:toxicity*; D000945:Antigens, Differentiation, T-Lymphocyte / Q000276:immunology*; D017252:CD3 Complex; D006801:Humans; D007035:Hypothermia; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D007668:Kidney / Q000187:drug effects / Q000473:pathology / Q000502:physiology; D051379:Mice; D008811:Mice, Inbred DBA; D008954:Models, Biological; D016853:Muromonab-CD3; D011948:Receptors, Antigen, T-Cell / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
D000911:Antibodies, Monoclonal; D000945:Antigens, Differentiation, T-Lymphocyte; D017252:CD3 Complex; D016853:Muromonab-CD3; D011948:Receptors, Antigen, T-Cell; D014409:Tumor Necrosis Factor-alpha