A deficiency chromosome in Drosophila alters neuritic projections in an identified motoneuron.
The tergotrochanteral muscles (TTM) in the second thoracic segment of the fruitfly, Drosophila melanogaster, power the jump-escape response. The cell bodies of the motoneurons innervating these muscles, located in the thoracico-abdominal ganglion, have prominent posterior and medial neurites. While in wildtype flies of the Canton-S (C-S) and Oregon-R (O-R) strains, the medial neurite of a TTM motoneuron rarely crossed the midline (C-S: 0/17; O-R: 2/8), in heterozygous flies with a deficiency at the base of the X-chromosome, Df(1)16-3-22, the medial neurite frequently crossed the midline (Df(1)16-3-22/C-S: 7/12; Df(1)16-3-22/O-R: 18/22).
Swain
G P
GP
Department of Neuroscience and Cell Biology, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway 08854-5635.
Wyman
R J
RJ
Egger
M D
MD
D000818:Animals; D001369:Axons / Q000648:ultrastructure*; D002874:Chromosome Mapping; D004331:Drosophila melanogaster / Q000235:genetics* / Q000648:ultrastructure; D005260:Female; D005787:Gene Frequency / Q000235:genetics; D005838:Genotype; D008297:Male; D009046:Motor Neurons / Q000648:ultrastructure*; D014960:X Chromosome