[Changes in sleep in Parkinson's disease].
In a sample of 44 patients with Parkinson's disease, REM latency showed a unimodal rather than bimodal distribution, with peak frequency between 0-10 min. A total of 16 patients exhibited (36.4%) a sleep onset REM period (SOREMP-10); i.e. REM latency of 10 min during the night; an additional 4 patients (9%) showed REM latencies of 11-20 min, while 8 patients (18.2%) showed REM latencies of less than 50 min (63.6 of the total sample). Patients with REM latencies of less than 50 min were older, both at the time of study and at the age of onset of the disease. There were more patients with depressive syndrome in this group than in the other group. They also showed a higher sleep amount. No other clinical or polysomnographic differences were found between patients with short REM latencies and patients exhibiting REM latencies of more than 50 min. Very short REM latencies probably reflect depressive syndrome associated with Parkinson's disease.
Susitić
V
V
Kostić
V
V
Mihajlović
G
G
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000503:physiopathology*; D012895:Sleep, REM / Q000502:physiology*
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