The presence of a thyrotropin-releasing hormone-like factor in the grass shrimp (black tiger prawn, Penaeus monodon)
Immunoreactive (TRH) has been detected in acid and methanol extracts of hepatopancreas, in grass shrimp (black tiger prawn, Penaeus monodon). The evidence provided by the stimulation of thyrotropin (TSH) release from perfused rat anterior pituitary glands in vitro following the application of hepatopancreas extracts (SHE) reflected the presence of TRH-like substance in the shrimp. However, the molecular weight of the TRH-like substance estimated by gel filtration in SHE was greater than that of the synthetic TRH. Furthermore, other differences are also noted, e.g. TRH-like activity in SHE could not be completely neutralized by anti-TRH antiserum nor degraded in normal rat serum.
Hsieh
Y S
YS
Department of Physiology, Medical School, National Taiwan University, Taipei, Republic of China.
Fann
M C
MC
Wan
W C
WC
Wang
P S
PS
D000143:Acids; D000818:Animals; D002845:Chromatography; D008099:Liver / Q000378:metabolism; D010179:Pancreas / Q000378:metabolism; D033561:Penaeidae / Q000378:metabolism*; D010447:Peptide Hydrolases / Q000378:metabolism; D011863:Radioimmunoassay; D013973:Thyrotropin-Releasing Hormone / Q000378:metabolism*; D014020:Tissue Extracts / Q000378:metabolism
D000143:Acids; D014020:Tissue Extracts; D013973:Thyrotropin-Releasing Hormone; D010447:Peptide Hydrolases