Diversity of some gene frequencies in European and Asian populations. VI. Geographic patterns of PGM and ACP.
Genetic variation at the phosphoglucomutase-1 (PGM) and acid phosphatase (ACP) loci, in 160 and 120 European and Asian populations, respectively, is described by spatial autocorrelation statistics and directional variograms. Short-distance patterns of gene frequencies correspond to those predicted by models of isolation by distance, but long-range differentiation of populations is observed as well. A possible role of climatic selection in maintaining the PGM polymorphism is supported by the north-south orientation of the gradient for that locus, but not by biochemical evidence. By and large, the observed patterns of gene frequencies seem to reflect a combination of demographic processes, subdivision and isolation of local populations among them.
Farabegoli
A
A
Istituto di Zoologia, Università di Ferrara, Italy.
Barbujani
G
G
D000135:Acid Phosphatase / Q000235:genetics*; D001208:Asia; D005060:Europe; D005787:Gene Frequency; D014644:Genetic Variation; D005843:Geography; D006801:Humans; D010733:Phosphoglucomutase / Q000235:genetics*
D000135:Acid Phosphatase; D010733:Phosphoglucomutase