[Synthesis of phosphodiesters of 2-acetamido-2-deoxy-D-glucose--fragments of polymers of capsules from Escherichia coli K51 and Neisseria meningitidis X].
Hydrogenphosphonate method was used for synthesis of 4-nitrophenyl 2-acetamido-3- and 4-nitrophenyl 2-acetamido-4-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl phosphate)-2-deoxy-beta-D-glucopyranosides. The glycosides, phosphate diester fragments of the title bacteria capsular antigens, were obtained by H-phosphorylation of the suitably protected 2-acetamido-2-deoxy-beta-D-glucopyranosides with 2-acetamido-3,4,6-tri-O-benzoyl-2-deoxy-alpha-D-glucopyranosyl H-phosphonate in the presence of trimethylacetyl chloride followed by oxidation and deprotection.
Nikolaev
A V
AV
Ivanova
I A
IA
Shibaev
V N
VN
D004187:Disaccharides / Q000096:biosynthesis*; D004926:Escherichia coli / Q000378:metabolism*; D005958:Glucosephosphates / Q000096:biosynthesis*; D009345:Neisseria meningitidis / Q000378:metabolism*; D010084:Oxidation-Reduction
D004187:Disaccharides; D005958:Glucosephosphates
Sintez fosfodiéfirov 2-atsetamido-2-dezoksi-D-gliukozy--fragmentov polimerov kapsul Escherichia coli K51 i Neisseria meningitidis X.