Characteristics of clinical isolates of Pseudomonas aeruginosa. I. Resistance to serum bactericidal effect and production of proteolytic enzymes.
136 strains of Pseudomonas aeruginosa were tested for human serum bactericidal effect. Hundred (73%) of clinical isolates were resistant and 36 (27%) were effectively killed by human (undiluted or even 1000 times diluted) serum. Fifty six out of 136 (41.1%) had proteolytic activity and parallelly were resistant to bactericidal activity of normal human serum. Among serum susceptible strains only 6 out of 136 (4.4%) had proteolytic activity.
Pajdak
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E
Department of Clinical Immunology and Microbiology, Institute of Pediatrics, Medical School, Cracow.
Szkarłat
A
A
Kobylarz
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K
D001770:Blood Bactericidal Activity / Q000276:immunology; D006801:Humans; D066298:In Vitro Techniques; D010447:Peptide Hydrolases / Q000378:metabolism; D011552:Pseudomonas Infections / Q000209:etiology; D011550:Pseudomonas aeruginosa / Q000201:enzymology / Q000302:isolation & purification / Q000472:pathogenicity*
D010447:Peptide Hydrolases