[Lymphocyte subpopulations and the soluble interleukin-2 receptor in Hashimoto's thyroiditis and subacute thyroiditis].
There are no univocal experimental data in literature about T cell clone alterations in the peripheral blood during Hashimoto's thyroiditis (TH), autoimmune disease, and during subacute thyroiditis (TSA), an inflammatory thyroid lesion with possibility of "self-perpetuation". The object of our research was to examine the T cell clones, soluble fraction of interleukin 2 receptor and HLA-DR modifications in patients with TH and TSA compared with healthy population. Our results show significant increase of sIL-2r in the TSA compared with normal subjects and with patients TH, where on the contrary, a constant increase of HLA-DR was observed.
Aiello
A
A
Divisione di Medicina Generale, U.S.L. N. 5, Ospedale Regionale di Campobasso.
Cristofaro
M
M
Carrozza
F
F
Verdone
F
F
Carile
L
L
D000328:Adult; D005260:Female; D006684:HLA-DR Antigens / Q000032:analysis*; D006801:Humans; D016131:Lymphocyte Subsets; D008297:Male; D008875:Middle Aged; D015375:Receptors, Interleukin-2 / Q000032:analysis*; D013967:Thyroiditis, Autoimmune / Q000097:blood*; D013968:Thyroiditis, Subacute / Q000097:blood*
D006684:HLA-DR Antigens; D015375:Receptors, Interleukin-2
Studio delle sottopopolazioni linfocitarie e del recettore solubile dell'interleuchina-2 nella tiroidite di Hashimoto e nella tiroidite subacuta.