Non-enzymatic glycosylation of collagen and its relation to glycosylated haemoglobin in acute short-term diabetes.
Non-enzymatic glycosylation of collagen from rat-tail tendon was measured using the thiobarbitüric acid method in both normal and diabetic rats. Results were correlated with the glycosylated haemoglobin values. The non-enzymatic glycosylation of collagen increased in diabetics and showed a weak correlation with glycosylated haemoglobin (r = 0.735). Our findings showed that acute short-term diabetes can also cause an increase in non-enzymatic glycosylation of collagen and haemoglobin.
Yarat
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A
Faculty of Dentistry, Marmara University, Istanbul, Turkey.
Emekli
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N
D000208:Acute Disease; D000818:Animals; D003094:Collagen / Q000378:metabolism*; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism*; D005260:Female; D005947:Glucose / Q000378:metabolism; D006031:Glycosylation; D006454:Hemoglobins / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D012044:Regression Analysis
D006454:Hemoglobins; D003094:Collagen; D005947:Glucose