[Epileptogenic effect of quinolinic acid on the brain structures].
Data on the electrolytic lesions of the brain structures (striatum, dorsal hippocampus, amygdaloid complex) in rats suggest a trigger role of striatum in the formation of quinolinic acid (30 micrograms, intracerebroventricularly)--induced seizures. EEG recording also supports this conclusion.
Kozlovskiĭ
V L
VL
Prakh'e
I V
IV
D000679:Amygdala / Q000187:drug effects*; D000818:Animals; D003292:Convulsants / Q000008:administration & dosage*; D003342:Corpus Striatum / Q000187:drug effects*; D004195:Disease Models, Animal; D004827:Epilepsy / Q000139:chemically induced*; D006624:Hippocampus / Q000187:drug effects*; D007276:Injections, Intraventricular; D008297:Male; D017378:Quinolinic Acid; D011805:Quinolinic Acids / Q000008:administration & dosage*; D051381:Rats
D003292:Convulsants; D011805:Quinolinic Acids; D017378:Quinolinic Acid
Konvul'siogennoe deĭstvie khinolinovoĭ kisloty na mozgovye struktury.