Production of L-dopa by Aspergillus terreus.
Production of L-DOPA by the activity of tyrosinase from a strain of Aspergillus terreus 104 was investigated. Effects of substrate (L-tyrosine) concentrations, its mode of feeding to the assay mixture and also the effects of L-ascorbic acid and other antioxidants on the production rate of L-DOPA were studied. The parameters for optimal production of L-DOPA with a maximum conversion of 85% of 0.1% L-tyrosine were determined.
Chattopadhyay
S
S
Department of Microbiology, Bose Institute, Calcutta, India.
Das
A
A
D000975:Antioxidants / Q000378:metabolism; D001205:Ascorbic Acid / Q000378:metabolism; D001230:Aspergillus / Q000201:enzymology / Q000378:metabolism*; D003470:Culture Media; D007700:Kinetics; D007980:Levodopa / Q000378:metabolism*; D014442:Monophenol Monooxygenase / Q000378:metabolism; D013379:Substrate Specificity; D014443:Tyrosine / Q000378:metabolism
D000975:Antioxidants; D003470:Culture Media; D014443:Tyrosine; D007980:Levodopa; D014442:Monophenol Monooxygenase; D001205:Ascorbic Acid