Effect of a gonadotropin-releasing hormone analogue on the glucose metabolism in a diabetic patient.
We report a case of an insulin-dependent diabetic female who received leuprolide acetate and Depo-Lurpon for the treatment of endometriosis. Their use was associated with hyperglycemia and a deterioration in glucose control that necessitated changes in insulin dosage.
Coddington
C C
CC
Department of Obstetrics and Gynecology, Jones Institute for Reproductive Medicine, Eastern Virginia Medical School, Norfolk.
Hassiakos
D K
DK
Harrison
H C
HC
Brzyski
R G
RG
Jones
G S
GS
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001786:Blood Glucose / Q000187:drug effects*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D004715:Endometriosis / Q000188:drug therapy*; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000031:analogs & derivatives* / Q000627:therapeutic use; D006728:Hormones / Q000627:therapeutic use; D006801:Humans; D016729:Leuprolide
D000970:Antineoplastic Agents; D001786:Blood Glucose; D006728:Hormones; D007987:Gonadotropin-Releasing Hormone; D016729:Leuprolide