[Pituitary-gonadal hormonal evaluation in male patients with alcoholic liver cirrhosis].
Pituitary-gonadal plasmatic hormonal values were measured in 26 alcoholic cirrhotic males and 20 healthy subjects. Total testosterone and luteinizing hormone mean levels were lower in the cirrhotic group (p < 0.05). Estradiol and prolactin were significant higher (p < 0.05 and p < 0.001, respectively). Follicle stimulation hormone mean values were normal. Pituitary-gonadal axis luteinizing hormone-testosterone and follicle stimulating hormone-estradiol were abnormal since the retrofeedback mechanism failed to work in each system. These results show a wide disturbance of the sexual hormonal function in our patients which certainly contributes to puzzle the complexity of the clinical and therapeutic aspects in these kind of patients.
Kolster
J
J
Departamento de Medicina, Universidad de Carabobo.
Castro de Kolster
C
C
Bustillos
R
R
de Pool
I
I
Pepe
M
M
D000328:Adult; D004958:Estradiol / Q000097:blood; D005640:Follicle Stimulating Hormone / Q000097:blood; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006065:Gonadotropins, Pituitary / Q000097:blood*; D006801:Humans; D007006:Hypogonadism / Q000209:etiology; D008104:Liver Cirrhosis, Alcoholic / Q000097:blood* / Q000150:complications; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D008875:Middle Aged; D011388:Prolactin / Q000097:blood; D013739:Testosterone / Q000097:blood
D012739:Gonadal Steroid Hormones; D006065:Gonadotropins, Pituitary; D013739:Testosterone; D004958:Estradiol; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
Evaluación hormonal hipofiso-gonadal en pacientes masculinos con cirrosis hepática alcohólica.