Immunopharmacological indices of piroxicam.
The activity of piroxicam to the selected cellular immune reactions was studied. The drug was shown to modulate these processes, with the prevailing role of suppressive component. It was found that the mechanism of its effect partly consists in an interference in the activity of suppressor cells and mediators of immunological reactions.
Giełdanowski
J
J
Department of Experimental Therapy, Institute of Immunology and Experimental Therapy, Wrocław.
Kowalczyk-Bronisz
S H
SH
Błaszczyk
B
B
D000818:Animals; D000921:Antibody-Producing Cells / Q000187:drug effects; D003602:Cytotoxicity, Immunologic / Q000187:drug effects; D005260:Female; D007107:Immune System / Q000187:drug effects*; D007166:Immunosuppressive Agents; D066298:In Vitro Techniques; D007375:Interleukin-1 / Q000378:metabolism; D007694:Killer Cells, Natural / Q000187:drug effects; D016131:Lymphocyte Subsets / Q000187:drug effects; D051379:Mice; D008815:Mice, Inbred Strains; D010894:Piroxicam / Q000494:pharmacology* / Q000633:toxicity; D012397:Rosette Formation; D050378:T-Lymphocytes, Regulatory / Q000187:drug effects
D007166:Immunosuppressive Agents; D007375:Interleukin-1; D010894:Piroxicam