title: Calcium channel blockers and terbutaline--a positive interaction.
abstract: The role of two calcium channel blockers, nifedipine and verapamil was investigated in patients of bronchial asthma. Both the drugs given orally produced an insignificant rise in PEFR, FEF25-75% and FEV1. Given along with terbutaline, however, these drugs produced significantly greater increase in PEFR, FEF25-75% and FEV1 as compared to patients receiving terbutaline alone. The two calcium channel blockers also inhibited the terbutaline induced tremors and palpitation.
authors: Hospital for Chest and Tuberculosis, Jaipur.
authors: T N
authors: TN
authors: Sharma
authors: R
authors: R
authors: Gulati
authors: P R
authors: PR
authors: Gupta
authors: R L
authors: RL
authors: Goyal
authors: S D
authors: SD
authors: Gupta
authors: M
authors: M
authors: Bhatnagar
mesh_terms: D000328:Adult; D001249:Asthma / Q000188:drug therapy*; D002121:Calcium Channel Blockers / Q000008:administration & dosage / Q000627:therapeutic use*; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008297:Male; D009543:Nifedipine / Q000008:administration & dosage / Q000627:therapeutic use; D015656:Respiratory Mechanics / Q000187:drug effects; D013726:Terbutaline / Q000008:administration & dosage / Q000494:pharmacology*; D014700:Verapamil / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D002121:Calcium Channel Blockers; D014700:Verapamil; D009543:Nifedipine; D013726:Terbutaline