[Chronic altitude-induced pulmonary heart disease and the status of the adrenergic receptor system].
Clinical and functional features and status of the adrenoceptor system were studied in 182 mountaineers. With progressing right ventricular hypertrophy, the subjects were found to have elevated pulmonary blood pressure, increased anterior wall thickness of the right ventricle, decreased receptor densities on the surface of a cell, higher beta-receptor affinity and beta-adrenoceptor-adenylatecyclase complex dissociation.
Meĭmanaliev
T S
TS
Aldashev
A A
AA
Borbugulov
U M
UM
Bekbasarova
Ch B
ChB
D000293:Adolescent; D000328:Adult; D000531:Altitude; D000532:Altitude Sickness / Q000503:physiopathology*; D006332:Cardiomegaly / Q000209:etiology / Q000503:physiopathology; D002395:Catecholamines / Q000097:blood*; D002908:Chronic Disease; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology / Q000503:physiopathology; D000860:Hypoxia / Q000503:physiopathology*; D066298:In Vitro Techniques; D007707:Kyrgyzstan; D007963:Leukocytes, Mononuclear / Q000502:physiology*; D008875:Middle Aged; D011660:Pulmonary Heart Disease / Q000209:etiology / Q000503:physiopathology*; D011941:Receptors, Adrenergic / Q000502:physiology*; D013620:Tajikistan
D002395:Catecholamines; D011941:Receptors, Adrenergic
Khronicheskoe vysokogornoe legochnoe serdtse i sostoianie adrenoretseptornoĭ sistemy.