Two siblings with the Chiari I malformation.
Two siblings with symptoms characteristic of the Chiari I malformation are described. The malformations were confirmed by magnetic resonance imaging scans and at surgery. Upon review of the world literature, no instance of the Chiari I malformation in a single family has been reported.
Herman
M D
MD
Division of Neurosurgery, Childrens Memorial Hospital, Northwestern University, Chicago, Ill.
Cheek
W R
WR
Storrs
B B
BB
D001139:Arnold-Chiari Malformation / Q000175:diagnosis / Q000235:genetics* / Q000601:surgery; D002675:Child, Preschool; D003399:Craniotomy; D005260:Female; D006801:Humans; D007223:Infant; D007796:Laminectomy; D008279:Magnetic Resonance Imaging; D008297:Male; D009460:Neurologic Examination