Elevated levels of N-acetyl-beta-glucosaminidase in affective disorders and chemical dependence.
Levels of N-acetyl-beta-glucosaminidase (NAG) were examined in 575 patients with various psychiatric diagnoses and 38 non-ill controls. Ten percent of affectively disordered patients and 19% of chemically dependent patients had abnormal NAG levels, whereas none of the 38 controls did (P less than 0.05 and P less than 0.003 respectively). Other psychiatric diagnostic groups were not associated with abnormal levels of this enzyme.
Garvey
M
M
Department of Psychiatry, University of Iowa College of Medicine, Iowa City.
Noyes
R
R
Cook
B
B
Barrickman
L
L
Noel
M
M
Ghosheh
R
R
D000118:Acetylglucosaminidase / Q000652:urine*; D000275:Adjustment Disorders / Q000175:diagnosis; D000328:Adult; D001714:Bipolar Disorder / Q000175:diagnosis; D003866:Depressive Disorder / Q000175:diagnosis* / Q000201:enzymology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000175:diagnosis; D011569:Psychiatric Status Rating Scales; D019966:Substance-Related Disorders / Q000175:diagnosis* / Q000201:enzymology
D000118:Acetylglucosaminidase