[Clinical significance of nocturnal blood pressure and blood pressure variability: analysis of 522 cases].
Purpose of the study was to investigate whether and to what extent blood pressure variability and average night-time blood pressure are related to cardiovascular complications in hypertension. To this aim 60 normotensive and 462 hypertensive subjects were studied by means of non-invasive 24 hour blood pressure monitoring, using either the Avionics, or the ICR Spacelabs, or the Takeda system. Each subject was attributed a target organ damage score on the basis of 12-lead electrocardiogram, chest X-ray and fundoscopy, starting from 0 (no damage) up to 5 (maximum degree of damage). The 522 subjects were subsequently subdivided into 5 classes of increasing average daytime diastolic blood pressure. In each class a higher degree of cardiovascular complications was present in the subjects with the higher blood pressure variability and the higher average night-time blood pressure. From these results it may be inferred that both blood pressure variability and night-time blood pressure are related to the degree of target organ damage in hypertension. This stresses the importance of recording blood pressure throughout the 24 hours.
Palatini
P
P
Clinica Medica I, Università degli Studi, Padova.
Mormino
P
P
Martina
S
S
Businaro
R
R
Penzo
M
M
Racioppa
A
A
Guzzardi
G
G
Anaclerio
M
M
Pessina
A C
AC
D000328:Adult; D001794:Blood Pressure; D015924:Blood Pressure Monitors; D006332:Cardiomegaly / Q000209:etiology; D002318:Cardiovascular Diseases / Q000209:etiology; D002940:Circadian Rhythm; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000209:etiology
Significato clinico della pressione notturna e della variabilità pressoria: analisi di 522 casi.