Problems in diabetes mellitus management. Insulin resistance.
Insulin resistance is a cause for morning hyperglycemia seen in diabetic patients. Other reasons for morning hyperglycemia should be eliminated by performing an insulin response test. Once insulin resistance has been established as the cause of hyperglycemia, a step-by-step process should be used to establish the cause of the insulin resistance. Common causes of insulin resistance include hyperadrenocorticism, acromegaly, hyperthyroidism, and obesity. Hepatic disease, renal insufficiency, and sepsis are other causes of insulin resistance in practice. Less common causes include insulin antibodies, pregnancy, neoplasia, hyperandrogenism, and pheochromocytoma. If the underlying cause cannot be found or resolved, then increased doses of insulin are required to manage the hyperglycemia.
Wolfsheimer
K J
KJ
Department of Veterinary Physiology, Pharmacology & Toxicology, School of Veterinary Medicine, Lousiana State University, Baton Rouge 70803.
D000818:Animals; D002371:Cat Diseases / Q000188:drug therapy*; D002415:Cats; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000188:drug therapy / Q000662:veterinary*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy / Q000662:veterinary*; D004283:Dog Diseases / Q000188:drug therapy*; D004285:Dogs; D007333:Insulin Resistance