Treatment of non-allergic nasal hypersecretion with ipratropium and beclomethasone.
The effect of ipratropium and beclomethasone administered as nasal aerosols was compared in a double-blind, double-dummy, randomized, cross-over designed study. Twenty-four patients with non-allergic, watery hypersecretion participated in the trial. According to the patients' daily registration of nasal symptoms, no significant difference could be found between the two drugs. It was not possible to characterize patients who would benefit from treatment with either ipratropium or beclomethasone.
Jessen
M
M
Dept. of O.R.L., Malmö General Hospital, University of Lund, Sweden.
Bylander
A
A
D000280:Administration, Inhalation; D000336:Aerosols; D001286:Atropine Derivatives / Q000627:therapeutic use*; D001507:Beclomethasone / Q000008:administration & dosage / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D009241:Ipratropium / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D016032:Randomized Controlled Trials as Topic; D012223:Rhinitis, Vasomotor / Q000188:drug therapy*
D000336:Aerosols; D001286:Atropine Derivatives; D009241:Ipratropium; D001507:Beclomethasone