[Exudative enteropathy caused by an acute graft-vs-host reaction. Apropos of a case report].
The authors report the case of a 41-year-old woman who developed an acute graft-versus-host disease following bone marrow transplantation for post-polycythemic myeloid metaplasia; liver, cutaneous and intestinal lesions were present, associated, with a severe protein-losing enteropathy. Symptoms, diagnostic procedures and therapy of intestinal graft-versus-host disease are reviewed. The intestinal clearance of alpha-1 antitrypsin was particularly useful to assess the response to medial treatment, which induced a complete remission.
Ghilain
J M
JM
Services d'Hématologie et de Gastro-entérologie, Cliniques St-Luc, Université Catholique de Louvain, Bruxelles.
Martiat
P
P
Fiasse
R
R
Ferrant
A
A
Michaux
J L
JL
D000328:Adult; D016026:Bone Marrow Transplantation; D005260:Female; D006086:Graft vs Host Disease / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D055728:Primary Myelofibrosis / Q000628:therapy; D011504:Protein-Losing Enteropathies / Q000209:etiology*; D000515:alpha 1-Antitrypsin / Q000737:chemistry
D007166:Immunosuppressive Agents; D000515:alpha 1-Antitrypsin
Entéropathie exsudative causée par une réaction aiguë du greffon contre l'hôte. A propos d'une observation.