[Further development of P. multocida vaccines for swine].
149 strains with antigen fractions of both A and D type could be found out of 446 P. multocida field strains of porcine origin. Most of them are producing the dermonecrotizing toxin. These A/D strains proved to be virulent in mice and piglets as well. In mice, the vaccination with one of the most virulent and immunogenic A/D strains, inactivated and A1(OH)3 adsorbed caused an immunity against challenge infections with P. multocida of types A, D and A/D. This effect could be confirmed on SPF piglets.
Schimmel
D
D
Institut für bakterielle Tierseuchenforschung Jena-Zwätzen, Akademie der Landwirtschaftswissenschaften.
D000818:Animals; D001428:Bacterial Vaccines; D051379:Mice; D010325:Pasteurella / Q000276:immunology* / Q000472:pathogenicity; D010326:Pasteurella Infections / Q000517:prevention & control / Q000662:veterinary*; D013047:Specific Pathogen-Free Organisms; D013552:Swine; D013553:Swine Diseases / Q000517:prevention & control*; D014611:Vaccination / Q000662:veterinary*; D015164:Vaccines, Inactivated; D014774:Virulence
D001428:Bacterial Vaccines; D015164:Vaccines, Inactivated
Zur Weiterentwicklung von P.-multocida-Vakzinen für das Schwein.