The influence of physical activity and posture on the antidepressant effect of sleep deprivation in depressed patients.
A possible role of the factors 'physical activity' and 'posture' in the antidepressant effect of a total night's sleep deprivation (TSD) was investigated in 30 patients with major depressive disorder. Fifteen patients underwent TSD under 'conventional' conditions, while the other 15 were kept in bed during TSD but were not permitted to sleep. There was no significant difference between the antidepressant effects of TSD in the two groups. This result suggests that it is wakefulness itself rather than changes in physical activity or posture that is involved in the mechanism of the antidepressant action of TSD.
Baumgartner
A
A
Psychiatrische Klinik und Poliklinik of the Klinikum Rudolf-Virchow (Charlottenburg), Freie Universität Berlin, Germany.
Sucher
N
N
D000328:Adult; D000368:Aged; D001143:Arousal; D001714:Bipolar Disorder / Q000523:psychology / Q000628:therapy*; D003866:Depressive Disorder / Q000523:psychology / Q000628:therapy*; D015444:Exercise; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011187:Posture; D011569:Psychiatric Status Rating Scales; D012892:Sleep Deprivation