[Evaluation of the therapeutic effect of albendazole on experimental and human infections by Hymenolepis nana].
With the objective of knowing adequately the spectrum of activity of albendazole against intestinal helminthiases, we made observations regarding hymenolepiasis caused by Hymenolepis nana. Two series of investigations were carried out: a) treatment of mice with single doses of either 25 or 50 mg/kg, repeated after ten days, using as controls animals treated with 25 mg/kg of praziquantel or not treated with any antiparasitic drugs; b) treatment of adults and children with 400 mg daily for three consecutive days, repeated after ten days.
Amato Neto
V
V
Laboratório de Investigação Médica-Parasitologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, Brasil.
Moreira
A A
AA
Ferreira
G M
GM
do Nascimento
S A
SA
Matsubara
L
L
Campos
R
R
Pinto
P L
PL
D000293:Adolescent; D000328:Adult; D015766:Albendazole / Q000627:therapeutic use*; D000818:Animals; D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D006925:Hymenolepiasis / Q000188:drug therapy*; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy*; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008875:Middle Aged
D015766:Albendazole
Avaliação da atividade terapêutica do albendazol sobre infecções experimentale e humana pela Hymenolepis nana.