[Toxic activities of the Ga-Sn alloy (Adlloy-OH) on nutritional condition and dental caries development in rats].
The toxic activities of Ga-Sn alloy (Adlloy-OH) in experimental rats, its relations to the nutritional condition and dental caries development, were studied for three months. Adlloy, 0.3 g or 3 g per body weight (kg), was fed orally with the basal diet consisting of casein, sucrose, bean oil, mineral, and vitamin mixtures. Biochemical assays of serum was carried out for total protein, albumin, calcium, inorganic phosphate, glucose, urea, creatine, alkaline phosphatase, GOT, and GPT. There was no convincing evidence of toxic effects on growth and biochemical data by the oral feeding of Addloy-OH.
Matsui
S
S
Department of Dental Pharmacology, Higashi-Nippon-Gakuen University.
Saruta
T
T
Matsumoto
Y
Y
Hikage
S
S
Nakade
O
O
Kaku
T
T
Endo
K
K
Sagara
M
M
Ohno
H
H
D000818:Animals; D001774:Blood Chemical Analysis; D003722:Dental Alloys / Q000633:toxicity*; D003731:Dental Caries / Q000209:etiology; D005260:Female; D005708:Gallium / Q000633:toxicity*; D006801:Humans; D009752:Nutritional Status / Q000187:drug effects; D051381:Rats; D014001:Tin / Q000633:toxicity*
C075320:Adlloy; D003722:Dental Alloys; D014001:Tin; D005708:Gallium