title: [Treatment of deep wounds with loss of tissue. Value of a 3 percent boric acid solution].
abstract: Following the finding of dramatic improvement in a deep wound with loss of substance treated with a 3 percent boric acid solution, 31 patients hospitalized in a surgical intensive care unit and holding such a wound initially unimproved by classical treatments were subjected, in 1987-88, to a short-time use of this solution. A case-control study retrospectively performed with 12 of the patients demonstrated that after wound granulation was obtained they returned to a normal care unit about three times more rapidly than patients receiving conventional antiseptics (means: 20 and 55 days respectively). This reduction in intensive care duration of stay for these 12 patients saved approximately 2 millions francs. Thus, the 3 percent boric acid solution may be considered an efficient alternative in the treatment of deep wounds with loss of substance, but it is delicate to handle because of toxicity.
authors: Service d'Hygiène hospitalière, CHRU Nancy, Hôpital de Brabois, Vandoeuvre.
authors: M F
authors: MF
authors: Blech
authors: C
authors: C
authors: Martin
authors: J
authors: J
authors: Borrelly
authors: P
authors: P
authors: Hartemann
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001888:Boric Acids / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012189:Retrospective Studies; D014945:Wound Healing / Q000187:drug effects*; D014946:Wound Infection / Q000517:prevention & control; D014947:Wounds and Injuries / Q000188:drug therapy*
chemical_list: D001888:Boric Acids; C032688:boric acid
vernacular_title: Traitement des plaies profondes avec perte de substance. Intérêt d'une solution d'acide borique à 3 p. 100.