[Severe hyponatremia in acute porphyria. Central pontine myelinolysis as a complication of its treatment].
Two patients developed severe hyponatremia attributed to inappropriate antidiuretic hormone secretion during a crisis of acute porphyria, and were treated with intravenous hypertonic sodium solution. One of them developed clinical and radiological findings of pontine and extrapontine myelinolysis, which may constitute a risk in the treatment of this complication.
Duhalde
M
M
Departamento de Endocrinología, Pontificia Universidad Católica de Chile.
Téllez
R
R
Michaud
P
P
Sepúlveda
E
E
D000208:Acute Disease; D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis / Q000209:etiology*; D003711:Demyelinating Diseases / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000150:complications / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D007177:Inappropriate ADH Syndrome / Q000150:complications; D011149:Pons; D011164:Porphyrias / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D011166:Porphyrins / Q000032:analysis
D011166:Porphyrins
Hiponatremia severa en porfiria aguda. Mielinolisis pontina central como complicación de su tratamiento.