Angiotensinogen in the developing rat fetal hindbrain and spinal cord from 18th to 20th day of gestation: an immunocytochemical study.
We have detected angiotensinogen immunoreactivity in the hindbrain and in the spinal cord of rat fetuses during the 18th to 20th day of gestation. In the 18th-day fetus, a few immunoreactive angiotensinogen cells are localized in precise brain areas. Their number sharply increase during the 19th and 20th day gestation period when there is an active cell differentiation and cell growth. These observations suggest a role of the renin-angiotensinogen system during cell growth and cell differentiation.
Sood
P P
PP
Department of Biosciences, Saurashtra University, Rajkot, India.
Richoux
J P
JP
Panigel
M
M
Bouhnik
J
J
Wegmann
R
R
D000808:Angiotensinogen / Q000378:metabolism*; D000818:Animals; D005314:Embryonic and Fetal Development / Q000502:physiology; D005260:Female; D005333:Fetus / Q000378:metabolism; D005865:Gestational Age; D007150:Immunohistochemistry; D011247:Pregnancy; D051381:Rats; D011919:Rats, Inbred Strains; D012249:Rhombencephalon / Q000196:embryology* / Q000378:metabolism; D013116:Spinal Cord / Q000196:embryology* / Q000378:metabolism
D000808:Angiotensinogen