[The effect of zinc chloride mouthwashes on caries-inducing plaque streptococci. 1. In vitro research on the antimicrobial efficacy of zinc chloride on reference strains of Streptococcus mutans (BHT), Streptococcus sanguis (HKop) and Streptococcus salivarius (NCTN 8618)].
The antimicrobial efficiency of zinc chloride solution in concentration from 0.1% to 2.0% and 0.2% chlorhexidine solution has been examined on the strains of reference in a comparative study. Three test methods were applied: the agar diffusion test, the dilution test and the suspension test. As was to be expected the antibacterial effect of the zinc chloride solution was dependent on concentration. Between 0.1% and 2.0% the zinc chloride solution showed a bacteriostatic effect on the strains of reference only; the application of higher concentrated solutions is not indicated intraorally. 0.2% chlorhexidine solution showed a bactericidal effect on the test germs.
Nossek
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Sektion Stomatologie, Medizinische Akademie, Dresden, DDR.
Dobl
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D002710:Chlorhexidine / Q000494:pharmacology; D002712:Chlorides / Q000494:pharmacology*; D003731:Dental Caries / Q000382:microbiology*; D003773:Dental Plaque / Q000382:microbiology*; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D006801:Humans; D009067:Mouthwashes / Q000494:pharmacology*; D012015:Reference Standards; D013291:Streptococcus / Q000187:drug effects*; D013295:Streptococcus mutans / Q000187:drug effects; D013298:Streptococcus sanguis / Q000187:drug effects; D015032:Zinc / Q000494:pharmacology*; D017967:Zinc Compounds
D002712:Chlorides; D009067:Mouthwashes; D017967:Zinc Compounds; C016837:zinc chloride; D015032:Zinc; D002710:Chlorhexidine
Einfluss von Zinkchloridmundspülungen auf kariesinduzierende Plaquestreptokokken. 1. Mitteilung: In vitro-Untersuchungen über die antimikrobielle Wirksamkeit von Zinkchlorid auf die Referenzstämme Streptococcus mutans (BHT), Streptococcus sanguis (HKop) und Streptococcus salivarius (NCTN 8618).