Methodological implications of simultaneous solid-phase peptide synthesis: a comparison of active esters.
Simultaneous competition and comparison methods have been used to compare the activities of a wide variety of reactive esters for solid phase peptide synthesis. The results generally conform to expectations from the literature; the most active being dinitrophenyl esters. Pentafluorophenyl esters provide the most suitable selection for routine use.
Hudson
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MilliGen/Biosearch, Division of Millipore, Novato, CA 94949-5728.
D001667:Binding, Competitive; D004952:Esters / Q000737:chemistry* / Q000378:metabolism; D008722:Methods; D010455:Peptides / Q000138:chemical synthesis*
D004952:Esters; D010455:Peptides