title: Guanidinoethanesulfonic acid--inhibitor of GABA uptake in rat cortical synaptosomes.
abstract: Guanidinoethanesulfonic acid (GES) and taurine inhibit [3H]GABA uptake in rat cortical synaptosomes. The inhibitory effects of GES are more potent than taurine. These findings may explain the pharmacologic effects of GES in the CNS.
authors: Department of Pharmacology, Texas Tech University Health Sciences Center, Lubbock 79430.
authors: Y P
authors: YP
authors: Li
authors: J B
authors: JB
authors: Lombardini
mesh_terms: D000818:Animals; D002540:Cerebral Cortex / Q000187:drug effects / Q000378:metabolism*; D014179:Neurotransmitter Uptake Inhibitors / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D013574:Synaptosomes / Q000187:drug effects / Q000378:metabolism*; D013654:Taurine / Q000031:analogs & derivatives* / Q000494:pharmacology; D005680:gamma-Aminobutyric Acid / Q000493:pharmacokinetics*
chemical_list: D014179:Neurotransmitter Uptake Inhibitors; D013654:Taurine; C009558:taurocyamine; D005680:gamma-Aminobutyric Acid