Atlantoaxial instability in Down syndrome--guidelines for screening and detection.
A community survey was conducted in all adults with Down syndrome living in three health districts to see if there was any correlation between radiological and neurological abnormalities which could indicate the presence of atlantoaxial instability. There was no difference in the proportion of individuals with neurological abnormalities in the group with radiological abnormalities suggestive of atlantoaxial instability (6/14) compared with individuals with normal X-rays (50/123) as determined by the chi square test (0.01463: not significant). The clinical and ethical implications for screening of people with Down syndrome living in the community are discussed in view of these findings.
Roy
M
M
Monyhull Hospital, Kings Norton, Birmingham.
Baxter
M
M
Roy
A
A
D000328:Adult; D001268:Atlanto-Axial Joint / Q000000981:diagnostic imaging; D003153:Community Health Services; D004314:Down Syndrome / Q000150:complications*; D004739:England; D004992:Ethics, Medical; D005260:Female; D006801:Humans; D007593:Joint Instability / Q000150:complications* / Q000000981:diagnostic imaging / Q000453:epidemiology; D008297:Male; D011859:Radiography; D012042:Registries