[Outcome of acute renal failure caused by voluntary ingestion of Cortinarius orellanus].
Orellanin poisoning is characterized by an acute renal failure which can be lethal if the appropriate treatment is not given. A 31-year old woman was admitted to hospital 10 days after she had deliberately ingested 2 raw carpophores of the mushroom Cortinarius orellanus. Acute renal failure (creatininaemia 1,100 mumol/l) developed, requiring 6 sessions of haemodialysis, one of plasmapheresis and the administration of diltiazem and aminoacids. Plasma and tissue assays of orellanin, the mushroom's toxin, were performed by two-dimensional thin layer chromatography. Before haemodialysis and 10 days after ingestion of the poison, the plasma contained orellanin. Eighteen months after the attempted suicide, the plasma creatinine level was 181 mumol/l.
Delpech
N
N
Laboratoire de Biochimie-Immunochimie, Centre hospitalier général, Perpignan.
Rapior
S
S
Cozette
A P
AP
Ortiz
J P
JP
Donnadieu
P
P
Andary
C
C
Huchard
G
G
D015082:2,2'-Dipyridyl / Q000031:analogs & derivatives / Q000506:poisoning*; D058186:Acute Kidney Injury / Q000209:etiology* / Q000628:therapy; D000328:Adult; D000363:Agaricales; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D009145:Mushroom Poisoning / Q000150:complications* / Q000628:therapy; D009183:Mycotoxins; D010956:Plasmapheresis; D011725:Pyridines / Q000506:poisoning*; D006435:Renal Dialysis; D013406:Suicide, Attempted
D009183:Mycotoxins; D011725:Pyridines; C030076:orellanine; D015082:2,2'-Dipyridyl
Evolution d'une insuffisance rénale aiguë par ingestion volontaire de Cortinarius orellanus.