title: Plasma atrial natriuretic factor concentration in a heart-lung transplant recipient.
abstract: Plasma concentration of atrial natriuretic factor, a polypeptide secreted by the heart, was measured in a heart-lung transplant recipient before operation and for 8 days after operation, until the patient died. Plasma atrial natriuretic factor level decreased in combination with the transplantation; after transplantation the peptide level varied within a wide range, correlating with diastolic pulmonary artery pressure (r = 0.93, p less than 0.01). The physiologic atrial natriuretic factor response to changes in right ventricular afterload thus seems to be preserved in the denervated heart.
authors: Department of Anesthesia, Helsinki University Central Hospital, Finland.
authors: M
authors: M
authors: Hynynen
authors: A L
authors: AL
authors: Harjula
authors: M
authors: M
authors: Salmenperä
authors: I
authors: I
authors: Tikkanen
authors: F
authors: F
authors: Fyhrquist
authors: S
authors: S
authors: Mattila
mesh_terms: D000328:Adult; D009320:Atrial Natriuretic Factor / Q000097:blood*; D016041:Heart-Lung Transplantation; D006801:Humans; D008297:Male; D011669:Pulmonary Wedge Pressure; D011863:Radioimmunoassay
chemical_list: D009320:Atrial Natriuretic Factor