title: Secretion of endogenous lithium in teleost kidneys as a probable reflection of Na+ and water secretion in their renal proximal tubules.
abstract: Unlike mammals with renal reabsorption of lithium (Li+), in freshwater and, particularly, marine teleosts net secretion of this trace element by kidneys was discovered. The ratio of Li+ natural concentration (measured by mass spectrometric isotope dilution technique) in urine to that in blood plasma--(U/P)Li--lies in the range 2-6 in the freshwater species and between 5 and 14 in marine species, i.e. as a rule it is essentially higher than the inulin concentration index (U/P)In. It is supposed that the in vivo observed lithium net secretion in whole kidney reflects and quantitatively estimates Na+ and water secretion in renal proximal tubules of teleosts.
authors: Laboratory of Comparative Biochemistry of Inorganic Ions, Sechenov Institute of Evolutionary Physiology and Biochemistry, Academy of Sciences U.S.S.R., Leningrad.
authors: D G
authors: DG
authors: Fleishman
authors: S P
authors: SP
authors: Gambaryan
authors: E A
authors: EA
authors: Lavrora
authors: V A
authors: VA
authors: Nikiforov
authors: A A
authors: AA
authors: Saulus
authors: V F
authors: VF
authors: Vasilieva
mesh_terms: D000818:Animals; D001834:Body Water / Q000378:metabolism*; D005399:Fishes / Q000378:metabolism*; D007444:Inulin / Q000032:analysis; D007668:Kidney / Q000378:metabolism*; D007687:Kidney Tubules, Proximal / Q000378:metabolism*; D008094:Lithium / Q000097:blood / Q000652:urine*; D012964:Sodium / Q000097:blood / Q000378:metabolism* / Q000652:urine
chemical_list: D007444:Inulin; D008094:Lithium; D012964:Sodium