title: Serum lactate dehydrogenase isoenzymes in breast tumours.
abstract: Total serum LDH and its isoenzymes were estimated in 10 female controls and 30 cases of breast lump (22 malignant, 6 benign and 2 breast abscess). In breast malignancy, there was a significant elevation of total LDH and LDH-3, LDH-4 and LDH-5 isoenzymes with a significant fall in LDH-1 and LDH-2 percentage value. Following therapy, there was a significant elevation in LDH-1 and LDH-2 towards normal with a significant fall in total serum LDH and LDH-4 and LDH-5 isoenzymes. The estimation was found to be helpful in assessing the response of patient to the therapy given.
authors: Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University.
authors: P
authors: P
authors: Khurana
authors: N
authors: N
authors: Tyagi
authors: A
authors: A
authors: Salahuddin
authors: S P
authors: SP
authors: Tyagi
mesh_terms: D001943:Breast Neoplasms / Q000201:enzymology*; D005260:Female; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000097:blood*
chemical_list: D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase