title: Intestinal transport in cystic fibrosis (CF).
abstract: Ion transport was measured in jejunal biopsies using short-circuit current (SCC) as an index of net electrogenic ion transport. Increases in SCC associated with stimulation of Cl- secretion were observed in control tissues, but CF tissues did not exhibit such a response, indicating a failure of intestinal Cl- secretion. The rise in SCC associated with Na(+)-linked glucose absorption was greater in CF tissues than in controls, reflecting an enhanced active absorption of glucose.
authors: Department of Biomedical Science, University Western Bank, Sheffield.
authors: J
authors: J
authors: Hardcastle
authors: C J
authors: CJ
authors: Taylor
authors: P T
authors: PT
authors: Hardcastle
authors: P S
authors: PS
authors: Baxter
authors: J
authors: J
authors: Goldhill
mesh_terms: D001693:Biological Transport, Active; D003550:Cystic Fibrosis / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D007408:Intestinal Absorption; D007477:Ions; D007583:Jejunum / Q000378:metabolism*
chemical_list: D007477:Ions