title: [Coronary effects of left ventricular hypertrophy associated with hypertension].
abstract: Left ventricular hypertrophy secondary to hypertension has been associated with a reduction of maximum coronary flow per unit mass as shown by the increase in the minimal threshold of coronary vascular resistance per gramme. This phenomenon has usually been attributed to an increase in muscle mass with absent or inadequate vascular compensation. However, chronic hypertension may induce a function reduction in coronary flow. In particular, it has been recently shown that coronary vascular resistances are influenced by a cardio-cardiac reflex involving the baroreceptor response. Left ventricular hypertrophy could alter the function of the ventricular receptors and favourise myocardial ischemia by preventing the adaptation of coronary flow to myocardial metabolic demands.
authors: Clinica Medica, 2a Facolta di Medicina, Napoli, Italia.
authors: B
authors: B
authors: Trimarco
authors: N
authors: N
authors: de Luca
authors: B
authors: B
authors: Ricciardelli
authors: G
authors: G
authors: Rosiello
authors: G
authors: G
authors: Lembo
authors: V
authors: V
authors: Rendina
authors: M
authors: M
authors: Raponi
authors: R
authors: R
authors: Marchegiano
authors: M
authors: M
authors: Volpe
mesh_terms: D006332:Cardiomegaly / Q000150:complications* / Q000503:physiopathology; D003327:Coronary Disease / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000503:physiopathology
vernacular_title: Effets coronariens de l'hypertrophie ventriculaire gauche associée à l'hypertension.