Clinical trial with 5-fluorouracil and leucovorin.
Many clinical trials with 5-fluorouracil and leucovorin have been reported. This combination therapy seems to play an important role in untreated advanced colorectal cancer. In other neoplasms (gastric, head and neck, breast cancer) further studies are required.
Palmieri
G
G
Istituto di Oncologia, II Facoltà di Medicina e Chirurgia, Università degli Studi di Napoli, Italy.
Gridelli
C
C
Airoma
G
G
Balestrino
M
M
Bisogno
A
A
Incoronato
P
P
Bianco
A R
AR
D000230:Adenocarcinoma / Q000188:drug therapy; D001943:Breast Neoplasms / Q000188:drug therapy; D015179:Colorectal Neoplasms / Q000188:drug therapy; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005472:Fluorouracil / Q000627:therapeutic use*; D006258:Head and Neck Neoplasms / Q000188:drug therapy; D006801:Humans; D002955:Leucovorin / Q000627:therapeutic use*; D015201:Meta-Analysis as Topic; D013274:Stomach Neoplasms / Q000188:drug therapy
D002955:Leucovorin; D005472:Fluorouracil