title: HLA-DP antigens in HIV-infected individuals.
abstract: We studied the distribution of HLA-DP antigens in 74 HIV-infected Danish homosexual men and 188 ethnically matched healthy individuals, using the primed lymphocyte typing (PLT) technique. Forty of the patients developed AIDS within 3 years after diagnosis, whereas the remaining 34 were healthy or had only minor symptoms for 3 years or more (median observation time was 42 months). HLA-DPwl seemed to be decreased (relative risk = 0.3) in AIDS patients (5.0 per cent) when compared to patients with minor symptoms (14.7 per cent) and healthy controls (14.9 per cent). These differences were, however, not statistically significant. There were no other apparent deviations between patients (or subgroups of patients) and controls.
authors: Tissue Typing Laboratory, State University Hospital, Copenhagen, Denmark.
authors: N
authors: N
authors: Odum
authors: J
authors: J
authors: Georgsen
authors: L
authors: L
authors: Fugger
authors: J
authors: J
authors: Møller
authors: B K
authors: BK
authors: Jakobsen
authors: B
authors: B
authors: Hofmann
authors: P
authors: P
authors: Skinhøj
authors: M
authors: M
authors: Klokker
authors: E
authors: E
authors: Dickmeiss
authors: A
authors: A
authors: Svejgaard
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology*; D004198:Disease Susceptibility; D005819:Genetic Markers; D015658:HIV Infections / Q000276:immunology*; D006682:HLA-DP Antigens / Q000032:analysis*; D006801:Humans; D007959:Lymphocyte Culture Test, Mixed; D008297:Male; D012307:Risk Factors
chemical_list: D005819:Genetic Markers; D006682:HLA-DP Antigens