Purpuric contact dermatitis to benzoyl peroxide.
Patch test reactions in a patient with purpuric contact dermatitis to 5% benzoyl peroxide are described. Alterations of the capillary endothelium included obliteration of the lumina with perivascular mononuclear cell infiltrates. There were no epidermal alterations. These observations are discussed with reference to the data in the literature on vascular damage in "dermal" contact dermatitis.
van Joost
T
T
Department of Dermato-Venereology, Erasmus University, Rotterdam, The Netherlands.
van Ulsen
J
J
Vuzevski
V D
VD
Naafs
B
B
Tank
B
B
D000328:Adult; D001585:Benzoyl Peroxide / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D010328:Patch Tests / Q000379:methods; D010545:Peroxides / Q000009:adverse effects*; D011693:Purpura / Q000139:chemically induced*
D010545:Peroxides; D001585:Benzoyl Peroxide