title: [Synaptic localization of 5'-nucleotidase activity in the cerebellar cortex in adult rats irradiated by X rays after birth].
abstract: 5'-nucleotidase cytochemistry was performed in the cerebellum of adult rats exposed previously to a single postnatal X-irradiation which maintains until adulthood the normally transient multiple innervation of cerebellar Purkinje cells by climbing fibers. 5'-nucleotidase activity persists in climbing fiber synapses and other asymmetrical synapses while it is transient during normal development. Therefore, in the X-irradiated rat, an immature stage of the excitatory synapses persists which, for the climbing fibers, coïncides with or precedes their involution during normal development.
authors: Laboratoire de Neurobiologie du Développement, Institut des Neurosciences, C.N.R.S., Paris.
authors: Y
authors: Y
authors: Bailly
authors: S W
authors: SW
authors: Schoen
authors: N
authors: N
authors: Delhaye-Bouchaud
authors: G W
authors: GW
authors: Kreutzberg
authors: J
authors: J
authors: Mariani
mesh_terms: D015720:5'-Nucleotidase / Q000378:metabolism*; D000818:Animals; D000831:Animals, Newborn; D002525:Cerebellar Cortex / Q000201:enzymology* / Q000528:radiation effects; D016371:Cranial Irradiation / Q000009:adverse effects; D051381:Rats; D011919:Rats, Inbred Strains; D013569:Synapses / Q000201:enzymology*
chemical_list: D015720:5'-Nucleotidase
vernacular_title: Localisation synaptique de l'actitivé 5'-nucléotidase dans le cortex cérébelleux du rat adulte irradié aux rayons X après la naissance.