title: Comparison of perfusion lung scanning and angiography in the estimation of vascular obstruction in acute pulmonary embolism.
abstract: To determine the relationships between perfusion scan defect and angiographic severity (Miller index) in acute pulmonary embolism, we analysed examinations obtained before and after thrombolytic therapy in 34 consecutive patients free from underlying cardiopulmonary disease. The overall agreement between the two techniques was excellent (r = 0.82; mean absolute difference = 2.8%), although when embolic involvement was extensive (greater than 50% angiographic obstruction), the perfusion scan moderately underestimated (4%) the defect seen angiographically. These findings suggest that the pulmonary lung scan is a reliable method of assessing the initial pulmonary vascular obstruction as well as of quantifying any changes induced by or associated with the treatment.
authors: Division of Pneumology and Intensive Care, Laennec Hospital, Paris, France.
authors: G
authors: G
authors: Meyer
authors: M A
authors: MA
authors: Collignon
authors: F
authors: F
authors: Guinet
authors: A A
authors: AA
authors: Jeffrey
authors: L
authors: L
authors: Barritault
authors: H
authors: H
authors: Sors
mesh_terms: D000792:Angiography; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011651:Pulmonary Artery / Q000000981:diagnostic imaging*; D011655:Pulmonary Embolism / Q000175:diagnosis* / Q000188:drug therapy; D011877:Radionuclide Imaging; D013668:Technetium Tc 99m Aggregated Albumin; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use
chemical_list: D013668:Technetium Tc 99m Aggregated Albumin; D010959:Tissue Plasminogen Activator; D014568:Urokinase-Type Plasminogen Activator