Efficacy of cefoxitin for the prevention of postoperative infection in abdominal hysterectomy.
Prophylactic effect of cefoxitin against postoperative infection at a dose of 2 g intravenous (single dose 30 minutes before the operation) was investigated using fever index in patients who underwent the elective, nonradical abdominal hysterectomy. The results obtained are summarized as follows. Total fever index values were 12.9 +/- 10.0 degree-hours in the control group (n = 39), 11.3 +/- 9.7 degree-hours in the study group (n = 39). There were no statistical significance between both groups. Data from this investigation does not suggest the concept that prophylactic antibiotics are beneficial in the reduction of postoperative infection. The results of this prospective study reflected in unnecessity of antibiotic prophylaxis in abdominal hysterectomy.
Sutthijumroon
S
S
Department of Obstetrics and Gynecology, Faculty of Medicine, Prince of Songkla University, Thailand.
Chandeying
V
V
Tungphaisal
S
S
D000328:Adult; D002440:Cefoxitin / Q000008:administration & dosage / Q000627:therapeutic use*; D003556:Cystitis / Q000517:prevention & control; D005260:Female; D006801:Humans; D007044:Hysterectomy; D017053:Infection Control; D007239:Infections / Q000209:etiology; D008875:Middle Aged; D010249:Parametritis / Q000517:prevention & control; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies; D011897:Random Allocation; D013530:Surgical Wound Infection / Q000517:prevention & control*
D002440:Cefoxitin