Localization of atrial natriuretic peptide/cardiodilatin (ANP/CDD)-immunoreactivity in the lacrimal gland of the domestic pig.
The presence of atrial natriuretic peptic/cardiodilatin-immunoreactive material was demonstrated in the lacrimal gland of the domestic pig by high performance liquid chromatography and radioimmunoassay. The immunohistochemical localization revealed a distinct population of cuboid or spindle-shaped ANP/CDD-IR cells in the epithelium of the terminal portion of the secretory tubules. In addition, a moderate number of positive cells was localized intraepithelially in the intralobular ducts as well as the connective tissue between these ducts. Our findings provide a morphological indication that ANP/CDD may play a physiological role in the regulation of sodium transport and secretion in the lacrimal gland.
Lange
W
W
Department of Anatomy, University of Munich, F.R.G.
Lang
R E
RE
Basting
C
C
Unger
J W
JW
D000818:Animals; D009320:Atrial Natriuretic Factor / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid; D007765:Lacrimal Apparatus / Q000032:analysis*; D009124:Muscle Proteins / Q000032:analysis*; D011863:Radioimmunoassay; D013552:Swine
D009124:Muscle Proteins; D009320:Atrial Natriuretic Factor; C040651:cardiodilatin