Predicting preeclampsia.
Recent studies suggest that drugs affecting prostacyclin and thromboxane production may be able to affect the development of preeclampsia. In order to use these agents effectively, we must be able to select properly women at high risk. This review evaluates a number of historic and physical factors and laboratory tests that may aid in the prediction of preeclampsia. Family history, parity, and the roll-over test are currently the most efficient methods that are widely available. Two relatively new laboratory tests, plasma fibronectin concentration and urinary calcium/creatinine ratio, hold the greatest promise for the near future.
O'Brien
W F
WF
Department of Obstetrics and Gynecology, University of South Florida, College of Medicine, Tampa.
D000804:Angiotensin II; D000990:Antithrombin III / Q000032:analysis; D009320:Atrial Natriuretic Factor / Q000097:blood; D001794:Blood Pressure; D001798:Blood Proteins / Q000032:analysis; D002118:Calcium / Q000652:urine; D002298:Cardenolides; D004077:Digoxin; D005260:Female; D006801:Humans; D007501:Iron / Q000097:blood; D011225:Pre-Eclampsia / Q000175:diagnosis* / Q000503:physiopathology; D011247:Pregnancy; D012503:Saponins; D012709:Serum Albumin / Q000032:analysis; D014527:Uric Acid / Q000097:blood; D001620:beta-Thromboglobulin / Q000032:analysis
D001798:Blood Proteins; D002298:Cardenolides; D012503:Saponins; D012709:Serum Albumin; D001620:beta-Thromboglobulin; C034504:digoxin-like factors; D000804:Angiotensin II; D014527:Uric Acid; D004077:Digoxin; D009320:Atrial Natriuretic Factor; D000990:Antithrombin III; D007501:Iron; D002118:Calcium