[Pulmo cardialis: effect of inhaled bronchodilators on airway resistance of acute left ventricular dysfunction].
Disturbance of left ventricular function leads to an impairment of ventilation: airway resistance increases, while pulmonary compliance is reduced. We therefore studied the effect of inhalable bronchodilators (Fenoterol, Ipratropium bromide) on oscillatory airway resistance in 16 patients with an acute left heart failure. The results show that the resistance can be significantly reduced to normal values by the bronchodilators. Fenoterol has the greatest spasmolytic potency, but Ipratropium bromide is also effective. Recompensation of left heart function alone does not lead to comparable acute effects on airway resistance. The possibility of immediate improvement of ventilation through the use of inhalable bronchodilators should therefore be considered in the treatment of acute left heart failure.
Rasche
K
K
Medizinische Universitätsklinik und Poliklinik der Berufsgenossenschaftlichen Krankenanstalten Bergmannsheil Bochum.
Strunk
M
M
Höltmann
B J
BJ
Marek
W
W
Ulmer
W T
WT
D000403:Airway Resistance / Q000187:drug effects*; D001286:Atropine Derivatives / Q000008:administration & dosage*; D005280:Fenoterol / Q000008:administration & dosage*; D005665:Furosemide / Q000008:administration & dosage; D006333:Heart Failure / Q000188:drug therapy*; D006801:Humans; D009241:Ipratropium / Q000008:administration & dosage*; D012131:Respiratory Insufficiency / Q000188:drug therapy*
D001286:Atropine Derivatives; D005280:Fenoterol; D005665:Furosemide; D009241:Ipratropium
Pulmo cardialis: Effekt inhalativer Bronchodilatatoren auf den Atemwegswiderstand bei akuter linksventrikulärer Funktionsstörung.