[The molecular variants of thyroxine-binding protein and the concentration of a number of hormones in the blood in the postpartum period].
The serum concentrations of the total thyroxine-binding globulin (TBGt), its pregnancy-associated molecular variant (TBG-1), thyroxine, progesterone, estradiol, and prolactin were measured by radioimmunoassay in the course of the postpartum period (0-40 days) in women. High serum TBG-1 concentrations (an average of 36% of the level observed at the time of delivery) were unexpectedly detected in the late postpartum period (days 36-40) when the concentrations of TBGt, thyroxine, estradiol and progesterone were within normal. The presence of TBG-1 in the maternal blood for a long time after delivery may be caused by estrogen-dependent synthesis and secretion rather than by its slow clearance from the blood.
Sviridov
O V
OV
Kiseleva
E E
EE
Ermolenko
M N
MN
Shilko
A N
AN
Borodina
E I
EI
D000293:Adolescent; D000328:Adult; D002585:Cesarean Section; D005260:Female; D006728:Hormones / Q000097:blood*; D006801:Humans; D008970:Molecular Weight; D011184:Postoperative Period; D049590:Postpartum Period / Q000097:blood*; D011247:Pregnancy; D011645:Puerperal Infection / Q000097:blood; D013975:Thyroxine-Binding Proteins / Q000032:analysis*; D013997:Time Factors
D006728:Hormones; D013975:Thyroxine-Binding Proteins
Molekuliarnye varianty tiroksinsviazyvaiushchego globulina i kontsentratsiia riada gormonov v krovi v poslerodovom periode.