Pure red cell aplasia associated with essential thrombocythemia (a case report).
A rare case of erythroblastopenia associated with essential thrombocythemia (ET) is described. The patient had markedly elevated platelet count (5200 x 10(9)/1) and significant platelet dysfunction leading to extensive soft tissue and gastrointestinal hemorrhage. There was paucity of erythroid precursors in the bone marrow - a feature hitherto undescribed in ET. The thrombocytosis responded to well busulphan therapy but patient succumbed to fulminant infection consequent upon drug induced neutropenia.
Sarode
R
R
Department of Hematology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Bambery
P
P
Marwaha
N
N
Gupta
A
A
Garewal
G
G
Deodhar
S D
SD
D005260:Female; D006801:Humans; D008875:Middle Aged; D012010:Red-Cell Aplasia, Pure / Q000209:etiology*; D013920:Thrombocythemia, Essential / Q000150:complications* / Q000175:diagnosis