title: Abnormal genetic segregation associated with the presence of a Y. w+ chromosome in Drosophila melanogaster.
abstract: We have observed an abnormal genetic segregation in the progeny of crosses between males of the F71 (y wa/Y.w+) strain and females of various strains carrying marker mutations on their chromosome 2. The Y.w+ chromosome, previously described as possibly being associated with a translocation of the 22D region of chromosome 2, was shown to carry the 21A1-22E4 tip of the 2L chromosome. One chromosome 2 of F71 had a deletion of this region. The abnormal genetic segregation observed in the progeny of different crosses can be explained both by the partial lethality (which becomes severe in some homogeneous genetic backgrounds) due to trisomy of the 21A1-22E4 chromosome 2 fragment and by the lethality associated with monosomy of this 21A1-22E4 segment.
authors: Institut Jacques Monod, Université Paris, France.
authors: M
authors: M
authors: Rosenberg-Bourgin
authors: A
authors: A
authors: Bracone
authors: F
authors: F
authors: Lemeunier
authors: S
authors: S
authors: Aulard
authors: S
authors: S
authors: Paumard
authors: G
authors: G
authors: Contesse
mesh_terms: D000818:Animals; D003433:Crosses, Genetic; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D008297:Male; D009154:Mutation; D014178:Translocation, Genetic; D014314:Trisomy; D014998:Y Chromosome