title: Studies on nonspecific protection induced with OMP of Shigella flexneri and other genera of Enterobacteriaceae.
abstract: Outer membrane proteins (OMP) isolated from Shigella flexneri, Escherichia coli, Proteus vulgaris and Salmonella typhimurium were tested for their protective activity. Each OMP preparate given to mice intraperitoneally in a single injection (5 micrograms/per mouse) protected the animals not only in homologous but also in varying intensity in heterologous systems. Evidence was obtained that this nonspecific protection is cell mediated.
authors: Laboratory of Medical Microbiology, Polish Academy of Sciences, Wrocław.
authors: A
authors: A
authors: Czarny
authors: D
authors: D
authors: Witkowska
authors: M
authors: M
authors: Mulczyk
mesh_terms: D000818:Animals; D001425:Bacterial Outer Membrane Proteins / Q000276:immunology*; D003429:Cross Reactions; D004755:Enterobacteriaceae / Q000276:immunology*; D004756:Enterobacteriaceae Infections / Q000517:prevention & control; D004926:Escherichia coli / Q000276:immunology; D006968:Hypersensitivity, Delayed; D007111:Immunity, Cellular; D007116:Immunization, Passive; D051379:Mice; D008815:Mice, Inbred Strains; D011514:Proteus vulgaris / Q000276:immunology; D012486:Salmonella typhimurium / Q000276:immunology; D012763:Shigella flexneri / Q000276:immunology*
chemical_list: D001425:Bacterial Outer Membrane Proteins