title: Unusual lymphocyte subset distribution in some depressed patients.
abstract: Depression has been previously associated with immunologic dysfunction. The lymphocyte subsets of 10 patients with major depression were found to show a mean T4-T8 (helper-suppressor) ratio lower than that of controls, a difference attributable to increased numbers of suppressor cells in the depressed group. One possible cause of increased suppressor cells is prior or current viral infection.
authors: Department of Psychiatry, Massachusetts General Hospital, Boston.
authors: S N
authors: SN
authors: Wilson
authors: O S
authors: OS
authors: Surman
authors: R
authors: R
authors: Colvin
authors: D
authors: D
authors: Ozonoff
authors: A J
authors: AJ
authors: Gelenberg
authors: M A
authors: MA
authors: Jenike
authors: T
authors: T
authors: Manschreck
authors: C
authors: C
authors: Pato
mesh_terms: D000328:Adult; D003866:Depressive Disorder / Q000150:complications / Q000276:immunology*; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007958:Leukocyte Count; D008218:Lymphocytosis / Q000145:classification / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*; D014777:Virus Diseases / Q000150:complications / Q000276:immunology