Cytotec (misoprostol).
NSAIDs have been associated with gastric ulcers and life-threatening complications, including hemorrhage and perforation. Cytotec (misoprostol) is the only drug approved for the prevention of NSAID-induced gastric ulcers. The administration of Cytotec represents benefits, particularly to an elderly population in which the usage trend of NSAIDs is increasing and the induced gastric injury is often silent. The nurse must have an adequate knowledge of this medication in order to provide patients receiving this drug with appropriate patient instruction.
Swartz
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D000527:Alprostadil / Q000031:analogs & derivatives* / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D006801:Humans; D016595:Misoprostol; D013276:Stomach Ulcer / Q000139:chemically induced / Q000188:drug therapy*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D000897:Anti-Ulcer Agents; D016595:Misoprostol; D000527:Alprostadil