Duration of the microsomal enzyme (cytochrome b560ms) inducer action and imprinting potential of a steroid in Tetrahymena.
Tetrahymena subjected to a three-day exposure to the steroid triamcinolone exhibited a decreased microsomal enzyme activity, three days after treatment, followed by a slight and a considerable activity increase over the control at one and two weeks after treatment, respectively. Reexposure to triamicinolone after return to plain medium for three days accounted for a marked increase in the inducer action which, however, failed to persist for an appreciable time.
László
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Department of Biology, Semmelweis University Medical School, Budapest, Hungary.
Szeberényi
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Csaba
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D000818:Animals; D003573:Cytochrome b Group / Q000096:biosynthesis*; D042963:Electron Transport Complex II; D004790:Enzyme Induction / Q000187:drug effects; D008861:Microsomes / Q000187:drug effects / Q000201:enzymology*; D013769:Tetrahymena pyriformis / Q000187:drug effects / Q000201:enzymology*; D013997:Time Factors; D014221:Triamcinolone / Q000494:pharmacology*
D003573:Cytochrome b Group; D014221:Triamcinolone; C025355:cytochrome b560; D042963:Electron Transport Complex II