LHRH analogue for treatment of recurrent and refractory mastalgia.
The LHRH analogue Zoladex was used to treat 21 premenopausal women with severe recurrent or refractory breast pain. Severity and pattern of mastalgia, whether cyclical or non-cyclical, was assessed using self-administered record cards. Symptom relief was achieved in 17 (81%) of the patients. This study showed Zoladex to be an effective short-term treatment for refractory and recurrent mastalgia.
Hamed
H
H
ICRF Clinical Oncology Unit, Guy's Hospital, London.
Caleffi
M
M
Chaudary
M A
MA
Fentiman
I S
IS
D000328:Adult; D001940:Breast; D002064:Buserelin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002979:Climacteric / Q000187:drug effects; D003692:Delayed-Action Preparations; D005260:Female; D017273:Goserelin; D006801:Humans; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy*
D003692:Delayed-Action Preparations; D017273:Goserelin; D002064:Buserelin