title: Significance of common acute lymphoblastic leukemia antigen (cALLA) positive cells in bone marrow of children off therapy in complete remission.
abstract: Bone marrows from 21 children with acute lymphoblastic leukemia in complete remission (CR) and off therapy for 14 months to 10 years were examined by flow cytometry with a panel of monoclonal antibodies. Significant percentages of cALLA+ cells of low fluorescence intensity were present up to 9 years after CR. These results emphasize the need to interpret flow cytometry results in light of the findings that low intensity cALLA+ cells represent a normal population of immature, non-malignant lymphoid cells.
authors: Department of Pathology, Medical University of South Carolina, Charleston 29425.
authors: S E
authors: SE
authors: Self
authors: S
authors: S
authors: Morgan
authors: O
authors: O
authors: Grush
authors: M F
authors: MF
authors: La Via
mesh_terms: D000943:Antigens, Differentiation / Q000032:analysis*; D000951:Antigens, Neoplasm / Q000032:analysis*; D001853:Bone Marrow / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D015260:Neprilysin; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000276:immunology*
chemical_list: D000943:Antigens, Differentiation; D000951:Antigens, Neoplasm; D015260:Neprilysin