title: [Two cases of side effects of a fumaric acid ester--local therapy].
abstract: We report on two cases of adverse reactions to topical treatment with monoethyl fumarate. One patient suffering from atopic dermatitis reacted with contact dermatitis; the other, suffering from psoriasis, developed a generalized, partly pustulous exanthema as well as signs of systemic involvement, such as tachycardia and dyspnea. As the causative mechanism we suggest non-immunological contact urticaria syndrome.
authors: Krankenhäuser des Märkischen Kreises, Dermat. Abtlg., Lüdenscheid.
authors: P
authors: P
authors: Dücker
authors: B
authors: B
authors: Pfeiff
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced; D003875:Drug Eruptions / Q000209:etiology*; D004485:Eczema / Q000188:drug therapy*; D005260:Female; D005650:Fumarates / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D011565:Psoriasis / Q000188:drug therapy*
chemical_list: D005650:Fumarates; C061175:ethyl fumarate
vernacular_title: Zwei Fälle von Nebenwirkungen einer Fumarsäureester--Lokaltherapie.