Development of nephropathy in diabetic patients with a single kidney.
Six diabetic patients with either a nephrectomy or a congenitally single kidney, and who later developed diabetic nephropathy, are described. They represent about 3% of our diabetic population with nephropathy, and are the only patients in our clinic population known to have single kidneys. A reduced renal mass may augment the renal glomerular hyperfiltration associated with diabetes mellitus and increase the risk of later developing nephropathy.
Sampson
M J
MJ
Department of Diabetes, King's College Hospital, London, UK.
Drury
P L
PL
D000328:Adult; D000368:Aged; D003928:Diabetic Nephropathies / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007668:Kidney / Q000002:abnormalities*; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy