[Presence of antibodies to lectin CSL in the blood of patients with multiple sclerosis patients].
We have recently shown (Zanetta et al., Lancet, 335, 1990, pp. 1482-1484) that antibodies to the protein CSL (an endogenous lectin involved in myelination) are present in the cerebrospinal fluid of patients with multiple sclerosis. We report a preliminary study demonstrating that in the blood of the same patients high levels of anti-CSL antibodies are found.
Zanetta
J P
JP
Centre de Neurochimie du C.N.R.S., Strasbourg.
Warter
J M
JM
Lehmann
S
S
Tranchant
C
C
Kuchler
S
S
Vincendon
G
G
D000906:Antibodies / Q000097:blood / Q000134:cerebrospinal fluid*; D006801:Humans; D037102:Lectins / Q000276:immunology*; D009103:Multiple Sclerosis / Q000276:immunology*
D000906:Antibodies; D037102:Lectins; C059525:cerebellar soluble lectin
Présence d'anticorps dirigés contre la lectine CSL dans le sang de patients atteints de sclérose en plaques.