title: Formyl-methanofuran synthesis in Methanobacterium thermoautotrophicum.
abstract: The initial step of methanogenesis from CO2 is the formation of formyl-methanofuran (formyl-MFR) from methanofuran (MFR), CO2 and H2. The enzymology of this novel type of CO2 fixation reaction has been difficult to study because formyl-MFR synthesis is subject to a complex activation. Recently, however, a number of advances have made questions regarding formyl-MFR synthesis more approachable.
authors: Department of Microbiology, University of Illinois, Urbana 61801.
authors: T A
authors: TA
authors: Bobik
authors: A A
authors: AA
authors: DiMarco
authors: R S
authors: RS
authors: Wolfe
mesh_terms: D000445:Aldehyde Oxidoreductases / Q000378:metabolism*; D002245:Carbon Dioxide / Q000378:metabolism; D004579:Electron Transport; D019605:Euryarchaeota / Q000201:enzymology / Q000378:metabolism*; D005663:Furans / Q000378:metabolism*
chemical_list: D005663:Furans; D002245:Carbon Dioxide; C050842:formylmethanofuran; D000445:Aldehyde Oxidoreductases; C060639:formylmethanofuran dehydrogenase