The myelodysplastic syndromes. Case report and review.
The myelodysplastic syndromes are a heterogenous group of hematologic disorders of myeloid progenitor cells. Oral manifestations may be among the first signs and often reflect degrees of neutropenia or neutrophil dysfunction. A patient with persistent herpes labialis and severe oral mucosal ulceration in myelodysplastic syndrome is reported. The features of myelodysplasia are reviewed and their oral manifestations and significance to dental management outlined.
Flint
S R
SR
Bristol Dental Hospital, England.
Sugerman
P
P
Scully
C
C
Smith
J G
JG
Smith
M A
MA
D000212:Acyclovir / Q000627:therapeutic use; D000368:Aged; D000369:Aged, 80 and over; D002175:Candida / Q000302:isolation & purification; D003730:Dental Care for Persons with Disabilities; D006560:Herpes Labialis / Q000188:drug therapy; D006801:Humans; D008297:Male; D009061:Mouth Mucosa / Q000473:pathology; D009190:Myelodysplastic Syndromes; D009504:Neutrophils / Q000276:immunology; D013211:Staphylococcus aureus / Q000302:isolation & purification; D013281:Stomatitis, Aphthous / Q000473:pathology
D000212:Acyclovir