Alpha-1-proteinase inhibitor gene frequencies in Belgium.
The alpha-1-antitrypsin phenotype was determined in cord blood of 1345 Belgian newborns by isoelectric focusing in polyacrylamide gels. Proteinase inhibitor (PI) gene frequencies were calculated. The relative gene frequency of the M allele was 0.9245, and those of S and Z alleles were 0.0543 and 0.0167 respectively. I and F alleles were less represented. These results are in agreement with population studies of neighbouring countries.
Kimpen
J
J
Department of Microbiology, Dr. L. Willems-Instituut, Belgium.
Legius
E
E
Bosmans
E
E
Van Vaerenbergh
V
V
Ramon
A
A
Raus
J
J
D001530:Belgium; D005787:Gene Frequency; D006801:Humans; D007231:Infant, Newborn; D011897:Random Allocation; D000515:alpha 1-Antitrypsin / Q000235:genetics*
D000515:alpha 1-Antitrypsin