[Post-transfusion hepatitis iin Chile: the reference parameters].
Most cases of post-transfusion hepatitis correspond to infection by non-A non-B virus. Indirect test (ALT elevation, anti-HBc titers) have been used to detect the presence of this virus. We screened 692 blood donors and health personnel, measuring anti-HBc (n = 572), HBs antigen (340), and ALT serum levels (190). Positive results were obtained for anti-HBc in 1.7% and HBs in 0%. ALT levels were 25 +/- 12 u/l in males and 18 +/- 14 in females (p < 0.01). ALT levels above 45 u/l were found in 6% of subjects. ALT levels were not related to anti-HBc positiveness nor to alcohol intake. The possible risk of posttransfusion hepatitis related to increased ALT levels remains to be clarified by specific markers.
Ibarra
H
H
Instituto de Medicina, Facultad de Medicina, Universidad Austral de Chile.
Riedemann
S
S
Gómez
J C
JC
Reinhardt
G
G
Hochstein-Mintzel
V
V
Froesner
G
G
D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D001782:Blood Donors / Q000706:statistics & numerical data; D001803:Blood Transfusion / Q000706:statistics & numerical data; D016009:Chi-Square Distribution; D002677:Chile / Q000453:epidemiology; D005260:Female; D006526:Hepatitis C / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D008297:Male; D008505:Medical Staff, Hospital / Q000706:statistics & numerical data; D008875:Middle Aged; D015995:Prevalence; D012016:Reference Values; D065227:Transfusion Reaction
Hepatitis postransfusional en Chile: parámetros de referencia.