Fetal outcome following inadvertant administration of long-acting DTRP6 GnRH microcapsules during pregnancy: a case report.
Early follicular use of long-acting analogues of gonadotrophin releasing hormone (GnRH) in IVF programmes has caused some concern with respect to its teratogenic potential. In the case reported here, an injection of DTRP6 GnRH microcapsules was given in the 5th week of a spontaneous unsuspected pregnancy. No deleterious effect or teratogenesis of the embryo could be demonstrated at birth or 18 months later.
Golan
A
A
Department of Obstetrics and Gynaecology, Assaf Harofe Medical Centre, Zerifin, Israel.
Ron-el
R
R
Herman
A
A
Weinraub
Z
Z
Soffer
Y
Y
Caspi
E
E
D000328:Adult; D005260:Female; D005333:Fetus / Q000187:drug effects*; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome; D017329:Triptorelin Pamoate
D017329:Triptorelin Pamoate; D007987:Gonadotropin-Releasing Hormone