title: Biochemical evidence for mediatory role of 5-hydroxytryptamine in the uterotonic action of prostaglandin F2oc.
abstract: 5-Hydroxytryptamine (5-HT) is reported to be involved in endogenous prostaglandin (PG)--modulated as well as exogenous PG-induced pharmacological activities including oxytocic effect of PGE1 PGE2oc Biochemical parameters were undertaken for further studies into the possible role of 5-HT in the uterotonic effect of PGF2oc on isolated oestronised rat uterus. The results substantiate the involvement of endogenous 5-HT in the uterotonic effect of PGF2oc.
authors: Department of Pharmacology, University College of Medicine, Calcutta University, India.
authors: D
authors: D
authors: Bhattacharyya
authors: S
authors: S
authors: Bhattacharjee
authors: B N
authors: BN
authors: Nag
authors: C R
authors: CR
authors: Maity
authors: S K
authors: SK
authors: Bandyopadhyay
mesh_terms: D000818:Animals; D015237:Dinoprost / Q000494:pharmacology*; D005260:Female; D010134:Fenclonine / Q000494:pharmacology; D007213:Indomethacin / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D012701:Serotonin / Q000378:metabolism*; D014191:Tranylcypromine / Q000494:pharmacology; D014599:Uterus / Q000187:drug effects / Q000378:metabolism*
chemical_list: D012701:Serotonin; D014191:Tranylcypromine; D015237:Dinoprost; D010134:Fenclonine; D007213:Indomethacin