[Changes in the indicators of intracardiac hemodynamics in patients with post-infarction cardiosclerosis under the action of verapamil].
Echocardiography was used to examine the intracardiac hemodynamics, contractile and diastolic functions of the heart in 64 patients with postinfarction cardiosclerosis in the presence of eukinetic circulation and the effects of verapamil depending on the index of a cardiometric product (CMP). A relationship was found between the action of the drug and the sizes of the heart and severity of left ventricular hypertrophy. In patients with normal cardiometric parameters, the antianginal effect of the drug was achieved by peripheral arterial vasodilation and a significant rhythm slowness of heart performance. As the CMP index increased due to the antianginal effect of the drug, an effect of transient cardioplegia was prevalent. The value of the CMP index is an important indication of indirect assessment of the left ventricular dysfunction in patients with postinfarction cardiosclerosis concurrent with eukinetic circulation.
Komissarov
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VA
D006332:Cardiomegaly / Q000188:drug therapy; D003327:Coronary Disease / Q000188:drug therapy / Q000503:physiopathology*; D006321:Heart / Q000187:drug effects / Q000503:physiopathology*; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D009203:Myocardial Infarction / Q000503:physiopathology; D014664:Vasodilation / Q000187:drug effects; D014700:Verapamil / Q000494:pharmacology / Q000627:therapeutic use*
D014700:Verapamil
Izmeneniia pokazateleĭ vnutriserdechnoĭ gemodinamiki u bol'nykh postinfarktnym kardiosklerozom pod vliianiem verapamila.