[Mycosis fungoides--report of a case].
A 61-year-old female suffered from scaly, violaceous, reddish patches and plaques on the face, trunk and upper arms for two years. Histopathology showed that atypical lymphocytes had infiltrated the epidermis and dermis. Epidermotropism was noted but Pautrier microabscesses was not identified. The electron microscopy revealed the atypical lymphocytes had convoluted contour and peripheral hyperchromatic nuclei. By immunohistochemical study, the labelling of OKT4, OKT8 and OKT11 was positive for the cells, which appeared in the majority of helper T-cells, infiltrating the dermis. The diagnosis was mycosis fungoides, plaque stage. The patient received UVA therapy for 3 months but discontinued due to a worsening of her physical condition.
Chen
J Y
JY
Department of Dermatology, Kaohsiung Municipal Min Shen Hospital, Taiwan, Republic of China.
Hsieh
Y S
YS
Tseng
H M
HM
Fang
K T
KT
D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000175:diagnosis* / Q000473:pathology; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology; D006377:T-Lymphocytes, Helper-Inducer / Q000473:pathology / Q000648:ultrastructure