[Lipid metabolism in depressive syndromes with the symptoms of disorders of the cardiovascular and cerebrovascular systems during pharmacological treatment].
Rheoencephalographic research had been performed in 30 subjects (mean age = = 57) suffering from both endogenous depression and cardiovascular disorder showing the disturbance of lipid metabolism. The result of the reg assessment confirmed our previous observations pointing to existence of the cerebral blood flow disturbances in these patients: shorter time of the propagation of the wave (Ra) suggesting higher tonus of the precerebral arteries, shorter time of the period (b) pointing to an acceleration of the heart rhythm and the lower value of the ratio Hmax/hd pointing to the higher tonus of the intracerebral arteries. The rheoencephalographic indices correlated with the lipid metabolism parameters, especially with total lipids, HDL and LDL-cholesterol fractions. The results point to the need for simultaneous using both antidepressant and prophylactic anti-atherosclerotic therapy in these patients.
Strzyzewski
W
W
Katedry i Kliniki Psychiatrii AM w Poznaniu.
Szajnerman
Z
Z
Chłopocka-Woźniak
M
M
Zelechowska-Ruda
E
E
Jaracz
J
J
D000368:Aged; D000639:Amitriptyline / Q000008:administration & dosage*; D002561:Cerebrovascular Disorders / Q000150:complications / Q000378:metabolism* / Q000523:psychology; D003327:Coronary Disease / Q000150:complications / Q000378:metabolism* / Q000523:psychology; D003866:Depressive Disorder / Q000150:complications / Q000188:drug therapy / Q000378:metabolism*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000378:metabolism* / Q000523:psychology; D007099:Imipramine / Q000008:administration & dosage*; D050356:Lipid Metabolism; D008297:Male; D008875:Middle Aged
D000639:Amitriptyline; D007099:Imipramine
Badania nad gospodarka lipidowa w zespołach depresyjnych z objawami zaburzeń w układzie sercowo-naczyniowym i w krazeniu mózgowym krwi w przebiegu leczenia farmakologicznego.