Hairy cell leukemia involving an inguinal hernial sac.
A 37-year-old man with hairy cell leukemia was found incidentally to have a right inguinal hernia. Microscopic examination of the resected herniorrhaphy specimen disclosed dense transmural infiltration by hairy cells. Electron-microscopic and immunoperoxidase studies confirmed the presence of surface cytoplasmic projections and B cell phenotype, respectively, of the infiltrating cells. This case is, to our knowledge, the first reported instance of hairy cell leukemia involving a hernial sac and demonstrates the capacity of hairy cells to infiltrate unexpected soft-tissue sites.
Melaragno
M J
MJ
Department of Pathology, Ohio State University College of Medicine, Columbus.
Theil
K S
KS
Marsh
W L
WL
Sedmak
D D
DD
Bouroncle
B A
BA
D000328:Adult; D006552:Hernia, Inguinal / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007943:Leukemia, Hairy Cell / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D008297:Male; D009361:Neoplasm Invasiveness; D013154:Spleen / Q000473:pathology; D013156:Splenectomy