Cytogenetic analysis of 51 patients with chronic myeloid leukemia.
The Ph1 translocations were observed in 43 of the 51 patients with chronic myeloid leukemia (CML). Of the 43 patients with Ph1 chromosome, 19 (45%) had other structural abnormalities. Complex translocations were observed in 5 patients (12%). Twenty-eight patients with Ph1-positive CML have been followed up genetically.
Hu
N
N
Cancer Institute, Chinese Academy of Medical Sciences, Beijing.
Bian
M L
ML
Le Beau
M M
MM
Rowley
J D
JD
D006801:Humans; D007621:Karyotyping; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000235:genetics*; D014178:Translocation, Genetic