Genetic characterization of single cell clones isolated from a radiation induced lymphoma in mice carrying the T (1:17) 190 chromosome translocation.
Single cell clones were isolated in vivo from early passages of a highly variable lymphoma induced by gamma-irradiation in a TF-T190/+ mouse carrying the T/1:17/T190Ca chromosome translocation. The chromosome pattern, expression of the H-2 antigenic specificities determined by the T190 (1:17) translocation chromosomes and biological properties of the clones have been compared and discussed.
Włodarska
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Cancer Center of Maria Skłodowska-Curie Institute, Department of Tumor Biology, Warsaw.
D000818:Animals; D002869:Chromosome Aberrations; D002999:Clone Cells / Q000648:ultrastructure; D007621:Karyotyping; D008223:Lymphoma / Q000235:genetics*; D051379:Mice; D009368:Neoplasm Transplantation; D009381:Neoplasms, Radiation-Induced / Q000235:genetics*; D014178:Translocation, Genetic