Tuberculostatic activity of henna (Lawsonia inermis Linn.).
The tuberculostatic activity of the herb henna (Lawsonia inermis Linn.) was tested in vitro and in vivo. On Lowenstein Jensen medium, the growth of tubercle bacilli from sputum and of Mycobacterium tuberculosis H37Rv was inhibited by 6 micrograms/ml of the herb. In vivo studies on guinea pigs and mice showed that the herb at a dose of 5 mg/kg body weight led to significant resolution of experimental tuberculosis following infection with M. tuberculosis H37Rv.
Sharma
V K
VK
S. M. S. Medical College, Hospital for Chest and Tuberculosis, Jaipur, India.
D000818:Animals; D006168:Guinea Pigs; D066298:In Vitro Techniques; D051379:Mice; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects*; D009285:Naphthoquinones / Q000494:pharmacology / Q000627:therapeutic use*; D014376:Tuberculosis / Q000188:drug therapy*
D009285:Naphthoquinones; C005090:lawsone