title: [Cardiac arrest during anesthesia and recovery period].
abstract: Cardiac arrests (CA) occurring during anaesthesia and recovery can be classified into three groups: CA not related to anaesthesia (NACA), CA related to anaesthesia (ACA), whether partially (PACA) or totally (TACA). In the French survey, NACAs were three times more frequent than ACAs. Nearly 25% of ACAs occurred at induction and consisted mainly in TACAs. Another quarter of ACAs occurred during maintenance and consisted mainly in PACAs. About 50% of ACAs occurred after the end of anaesthesia and had the highest mortality rate. Cardiac arrest corresponds to the status of a heart unable to generate the minimum aortic blood flow required for functioning of vital organs. For the brain, a zero-blood flow of more than 4 seconds results in coma. Consequently CA exists when the time interval between two subsequent efficient systoles is greater than 4 seconds. Anaesthetic agents can result in CA by 1) overdose (absolute, relative), 2) anaphylactoid/anaphylactic reactions, 3) specific effects (acetylcholine-like effect, hyperkalaemia and malignant hyperthermia for succinylcholine; vagal effect of vecuronium and atracurium; cardiotoxicity of bupivacaine) and 4) drug interaction. In hypoxic CA, severe neurologic impairment often still exists at the time of onset of CA. The anaesthesia machine and controlled ventilation can induce CA by hypoxic ventilation, overdose of anaesthetic vapour, excessive CO2 reinhalation, hypoventilation, disconnection, excessive pressure in airways. Cardiac hypothermia can be a cause of CA as well as a cause of unsuccessful CPR. Massive infusion of unwarmed fluids and IPPV with unheated gases generate a temperature gradient within the heart which may result in severe arrhythmias and CA.(ABSTRACT TRUNCATED AT 250 WORDS)
authors: Département d'Anesthésie-Réanimation Chirurgicale, Hôpital de Hautepierre, Strasbourg.
authors: J C
authors: JC
authors: Otteni
authors: A
authors: A
authors: Steib
authors: T
authors: T
authors: Pottecher
mesh_terms: D000707:Anaphylaxis / Q000139:chemically induced / Q000150:complications; D000762:Anesthesia Recovery Period; D000768:Anesthesia, General / Q000009:adverse effects*; D000777:Anesthetics / Q000009:adverse effects*; D062787:Drug Overdose; D006306:Health Surveys; D006323:Heart Arrest / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D007036:Hypothermia, Induced / Q000009:adverse effects; D007040:Hypoventilation / Q000150:complications; D007442:Intubation, Intratracheal / Q000009:adverse effects; D003473:Neuromuscular Nondepolarizing Agents / Q000009:adverse effects; D011184:Postoperative Period; D011379:Prognosis; D012121:Respiration, Artificial / Q000009:adverse effects; D013390:Succinylcholine / Q000009:adverse effects
chemical_list: D000777:Anesthetics; D003473:Neuromuscular Nondepolarizing Agents; D013390:Succinylcholine
vernacular_title: Arrêt cardiaque pendant l'anesthésie et en phase de réveil.