Characterization of an acidic polysaccharide from the seeds of Malva verticillata stimulating the phagocytic activity of cells of the RES.
An acidic polysaccharide, designated as MVS-IVA, was isolated from the seeds of Malva verticillata. It showed a remarkable reticuloendothelial system potentiating activity in the carbon clearance test. Chemical and spectroscopic studies demonstrated that the polysaccharide is rich in alpha-L-arabinofuranose residues and possesses mainly an alpha-1,5-linked L-arabino-beta-3,6-branched-D-galactan structure accompanied with rhamnogalacturonan type units. Both alpha-1,3-linked L-arabinopyranose and beta-1,4-linked D-xylopyranose residues were also identified as component units. MVS-IVA contains a small amount of protein (3.3%).
Gonda
R
R
Kyoritsu College of Pharmacy, Tokyo, Japan.
Tomoda
M
M
Shimizu
N
N
Kanari
M
M
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000032:analysis / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D015394:Molecular Structure; D012157:Mononuclear Phagocyte System / Q000187:drug effects*; D010587:Phagocytosis / Q000187:drug effects*; D011134:Polysaccharides / Q000302:isolation & purification / Q000494:pharmacology*; D013047:Specific Pathogen-Free Organisms
D004365:Drugs, Chinese Herbal; D011134:Polysaccharides