Waldenstrom's macroglobulinemia presenting with pleuropulmonary and gastric manifestations.
A case of Waldenstrom's macroglobulinemia is reported in which the main clinical presentation was related to pulmonary infiltrations and pleural effusion. Serum protein studies demonstrated the characteristic monoclonal increase in immunoglobulin M (IgMK). Pleural and percutaneous lung biopsies showed dense lymphocytic infiltration. Gastric biopsy also showed focal atypical lymphoid hyperplasia. There was good clinical and radiological response to treatment with chlorambucil and prednisolone.
Yap
J C
JC
Department of Medicine III, Tan Tock Seng Hospital, Singapore.
Poh
S C
SC
D000368:Aged; D005260:Female; D005757:Gastritis, Atrophic / Q000150:complications; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D008171:Lung Diseases / Q000150:complications*; D008221:Lymphoid Tissue / Q000473:pathology; D010994:Pleura / Q000473:pathology; D010996:Pleural Effusion / Q000150:complications / Q000473:pathology; D013272:Stomach Diseases / Q000150:complications*; D008258:Waldenstrom Macroglobulinemia / Q000150:complications*