[Clinical experience with an anticholinergic spasmolytic cimetropium bromide in the treatment of patients with renal colic].
We treated 38 consecutive outpatients with ureter colic with a new anticholinergic spasmolytic agent, cimetropium bromide, in order to evaluate its efficacy in this condition. After assessing pain intensity by means of a visual analogic scale, we administered 5 mg i.v. Already after 30 minutes, 4 patients (11%) reported complete subsidence of pain. In 21 patients (55%) pain subsided almost completely within one hour. Eighteen patients required a second 5 mg i.v. injection after one hour; of these, 13 (72%) had complete regression or marked reduction of pain. Apart from dryness of the mouth which appeared in two cases after the second injection and was of moderate intensity, no side effects were observed.
Fornapiero
E
E
Divisione di Urologia, USL 4, Ospedale Provinciale di Fano.
Barone
A
A
Francolini
G
G
Pupita
F
F
D000208:Acute Disease; D000328:Adult; D000368:Aged; D003085:Colic / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010276:Parasympatholytics / Q000627:therapeutic use*; D012074:Remission Induction; D012602:Scopolamine Derivatives / Q000627:therapeutic use*; D014515:Ureteral Diseases / Q000188:drug therapy
D010276:Parasympatholytics; D012602:Scopolamine Derivatives; C016859:cimetropium
Esperienza clinica con uno spasmolitico anticolinergico, il cimetropio bromuro, nel trattamento di pazienti affetti da colica renale.