title: Fast atom bombardment mass spectrometry in the study of dopamine melanogenesis intermediates.
abstract: Fast atom bombardment was applied to the study of the intermediates of the reaction dopamine-tyrosinase after treatment with diazomethane. The identification of trimethoxyindoline, dopamine-o-quinone and dimethoxyindole was easily achieved by this ionization method, together with accurate mass measurements and collision experiments. The structures of these compounds are in agreement with those already hypothesized in studies on melanogenesis.
authors: Dipartimento di Scienze Farmaceutiche, Università di Padova, Italy.
authors: G
authors: G
authors: Allegri
authors: R
authors: R
authors: Arban
authors: C
authors: C
authors: Costa
authors: M
authors: M
authors: Biasiolo
authors: O
authors: O
authors: Curcuruto
authors: A
authors: A
authors: Pozzan
authors: P
authors: P
authors: Traldi
mesh_terms: D004298:Dopamine / Q000378:metabolism*; D008543:Melanins / Q000096:biosynthesis*; D014442:Monophenol Monooxygenase / Q000378:metabolism; D016339:Spectrometry, Mass, Fast Atom Bombardment
chemical_list: D008543:Melanins; D014442:Monophenol Monooxygenase; D004298:Dopamine