[The luliberin test as a criterion for assessing the prospect of stimulating ovulation with pergonal].
Differentiated clinico-hormonal investigation using diagnostic LH-RH testing made it possible to reveal various conditions of patients with hypogonadotropic amenorrhea. The expression of clinical signs of hypoestrogenemia corresponded to a degree of hormonal insufficiency. The investigation permitted the evaluation of the prospects of perganol-stimulated ovulation and a choice of an optimum initial drug dose. Patients with moderate estrogenic insufficiency responding positively to LH-RH, were shown promising for perganol therapy. Pregnancy was noted in 86.4%, the initial drug dose was 2-3 ampules per day. In negative LH-RH testing pregnancy was noted in 12% of the patients only. The stimulation of ovulation in such patients should be started with a daily dose of 4-5 ampules of pergonal.
Manuilova
I A
IA
Nazarenko
T A
TA
Mullabaeva
S M
SM
D000328:Adult; D000568:Amenorrhea / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy; D004341:Drug Evaluation; D004958:Estradiol / Q000097:blood; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D007987:Gonadotropin-Releasing Hormone; D006801:Humans; D007006:Hypogonadism / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy; D007986:Luteinizing Hormone / Q000097:blood; D008596:Menotropins / Q000627:therapeutic use*; D010062:Ovulation Induction / Q000379:methods*; D012189:Retrospective Studies; D013997:Time Factors
D007987:Gonadotropin-Releasing Hormone; D004958:Estradiol; D008596:Menotropins; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
Proba s liuliberinom kak kriteriĭ otsenki perspektivnosti stimuliatsii ovuliatsii pergonalom.