[Intramuscular etofenamate in the treatment of acute lumbago. Effectiveness and tolerance in comparison with intramuscular diclofenac-Na].
In a controlled multi-center single-blind study, the relative efficacy and tolerance of i.m. injectable preparations of etofenamat(e) and diclofenac sodium were investigated in 96 patients with acute lumbago. Treatment resulted in obvious improvement in function and reduction in pain, no statistical difference being found between the two drugs. In 43% of the patients treated with etofenamat(e) and 27% of those receiving diclofenac, the final medical report indicated very good therapeutic results. Under etofenamat(e) i.m. therapy, no side effects occurred, and in no case did treatment have to be discontinued. Under diclofenac, two patients experienced adverse reactions, one allergic exanthema, and the other itching and a sensation of heat. A further patient experienced no improvement after the first injection and discontinued treatment.
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Rheumaklinik, Bad Säckingen.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D001416:Back Pain / Q000188:drug therapy*; D004008:Diclofenac / Q000008:administration & dosage*; D005260:Female; D005439:Flufenamic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives*; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D016032:Randomized Controlled Trials as Topic; D016037:Single-Blind Method
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004008:Diclofenac; D005439:Flufenamic Acid; C015207:etofenamate
Etofenamat i.m. zur Behandlung der akuten Lumbago. Wirksamkeit und Verträglichkeit im Vergleich zu Diclofenac-Na i.m.