title: Serial measurement of blood flow in expanded tissue by laser Doppler velocimetry.
abstract: This study provides additional information about changes in blood flow in expanded tissue as measured by laser Doppler. Five one-kilogram albino Hartley guinea pigs were implanted with commercially available hemispheric expanders. The expanders were inflated every 3 days on four successive occasions. Blood flow measurements were taken on each animal just before each inflation, immediately after inflation, and then at 1, 2, 3, 4, and 24 hours after expansion. Measurement of flow changes immediately after each inflation of the expander showed that, initially, blood flow in the tissue overlying the expander recovered quickly, but as the expansion process was continued, the flow did not return to baseline values so rapidly. This might be an indication that tissue expansion in patients could be carried out more rapidly during the initial inflations, with increasing recovery periods between inflations as the expansion process continued.
authors: Department of Otolaryngology-Head and Neck Surgery, University of Iowa, Iowa City 52242.
authors: J W
authors: JW
authors: Canady
authors: C A
authors: CA
authors: Squier
authors: K M
authors: KM
authors: Kelly
authors: J
authors: J
authors: Bardach
mesh_terms: D000818:Animals; D006168:Guinea Pigs; D007834:Lasers; D009132:Muscles / Q000098:blood supply; D012039:Regional Blood Flow; D012212:Rheology; D012445:Sacrococcygeal Region; D012867:Skin / Q000098:blood supply*; D013997:Time Factors; D015626:Tissue Expansion; D014159:Transducers