title: Methotrexate sensitivity in Down's syndrome: a hypothesis.
authors: Department of Pharmacology and Toxicology, University of Bergen, Norway.
authors: P M
authors: PM
authors: Ueland
authors: H
authors: H
authors: Refsum
authors: B
authors: B
authors: Christensen
mesh_terms: D004314:Down Syndrome / Q000150:complications* / Q000378:metabolism; D004361:Drug Tolerance; D005493:Folic Acid Antagonists; D006710:Homocysteine / Q000378:metabolism; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000188:drug therapy*
chemical_list: D005493:Folic Acid Antagonists; D006710:Homocysteine; D008727:Methotrexate