[Relative frequency of glucose-6-phosphate dehydrogenase deficiency in jaundiced newborn infants in the metropolitan area of Monterrey, Nuevo León].
In order to estimate the frequency of G6PD deficiency in the icteric population of the Monterrey metropolitan área (MMA), in the state of Nuevo León, there were studied 829 newborn males were studied. It was found that 13 subjects were deficient of this enzyme, that is equivalent to a frequency of 1.57% and when this frequency was compared with the one that was found an a previous study in a random sample of newborn males (0.66%) no statistical difference was observed, but it was estimated that the icteric newborn males have a relative risk of 2.34 times higher than the population in general to be a G6PD deficient, and this fact suggests the necessity to establish this screening test as a routine for all icteric newborn males, in order to have an opportune detection and an appropriate counselling.
González-Quiroga
G
G
Subjefatura de Investigación Científica, IMSS Unidad de Investigación Biomédica del Noreste, Monterrey, N.L., México.
Ramírez del Río
J L
JL
Ortíz-Jalomo
R
R
García-Contreras
R F
RF
Cerda-Flores
R M
RM
Mata-Cárdenas
B D
BD
Garza-Chapa
R
R
D000328:Adult; D001789:Blood Group Antigens; D005260:Female; D005954:Glucosephosphate Dehydrogenase / Q000097:blood / Q000235:genetics; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000145:classification / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology* / Q000235:genetics; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D007567:Jaundice, Neonatal / Q000209:etiology*; D008297:Male; D008800:Mexico / Q000453:epidemiology; D012306:Risk
D001789:Blood Group Antigens; D005954:Glucosephosphate Dehydrogenase
Frecuencia relativa de la deficiencia de glucosa-6-fosfato deshidrogenasa (G6PD) en neonatos ictéricos del área metropolitana de Monterrey, Nuevo León.