title: Imaging of ovarian cancer with radiolabelled monoclonal antibodies.
abstract: This article presents the state of the art of immunoscintigraphy (IS) of ovarian cancer. We will review the monoclonal antibodies (MoAbs) used in clinical trials: (HMFG1/2, OC125, H317, H17E2, NDOG2 and 791T/36). We conclude that none of the afore mentioned MoAbs are clearly superior and that IS cannot yet replace laparotomy for the diagnosis of ovarian cancer but may have a role in the follow-up of ovarian cancer, in timing second-look surgery and assessing the response/TD treatment.
authors: Department of Diagnostic Radiology, University Hospital Leiden, The Netherlands.
authors: D L
authors: DL
authors: van Kranenburg
authors: M J
authors: MJ
authors: van Kroonenburgh
authors: J B
authors: JB
authors: Trimbos
authors: G J
authors: GJ
authors: Fleuren
authors: E K
authors: EK
authors: Pauwels
mesh_terms: D000911:Antibodies, Monoclonal; D005260:Female; D006801:Humans; D015201:Meta-Analysis as Topic; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging
chemical_list: D000911:Antibodies, Monoclonal