[Subacute necrotizing lymphadenitis (Kikuchi and Fugimoto's disease)].
Subacute necrotizing lymphadenitis preferently or exclusively located in the cervical area is often unilateral, self-limited and of probable viral origin. Women under 30 years of age are affected in 80% of cases. Cure is produced in 2 to 3 months although sometimes a much longer course may be observed. Recurrence in the same or other areas may also occur. The histological pattern is characteristic with foci of necrosis with dust-like nuclear rests, absence of neutrophils, scarcity of plasma cells and a notorious proliferation of T4, lymphoimmune histiocytes that partially or completely erase the lymphoid structure. The aspect of a non Hodgkin large cell lymphoma may be stimulated.
Etcheverry
R
R
Depto. de Hematología, Hospital del Salvador, Facultad de Medicina, Universidad de Chile, Santiago.
Cruz
R A
RA
Martínez
V
V
D000208:Acute Disease; D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008199:Lymphadenitis / Q000175:diagnosis / Q000473:pathology*; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis; D009336:Necrosis; D013577:Syndrome
Linfoadenitis necrotizante subaguda (enfermedad de Kikuchi y Fugimoto).