Secretion of endogenous lithium in teleost kidneys as a probable reflection of Na+ and water secretion in their renal proximal tubules.
Unlike mammals with renal reabsorption of lithium (Li+), in freshwater and, particularly, marine teleosts net secretion of this trace element by kidneys was discovered. The ratio of Li+ natural concentration (measured by mass spectrometric isotope dilution technique) in urine to that in blood plasma--(U/P)Li--lies in the range 2-6 in the freshwater species and between 5 and 14 in marine species, i.e. as a rule it is essentially higher than the inulin concentration index (U/P)In. It is supposed that the in vivo observed lithium net secretion in whole kidney reflects and quantitatively estimates Na+ and water secretion in renal proximal tubules of teleosts.
Fleishman
D G
DG
Laboratory of Comparative Biochemistry of Inorganic Ions, Sechenov Institute of Evolutionary Physiology and Biochemistry, Academy of Sciences U.S.S.R., Leningrad.
Gambaryan
S P
SP
Lavrora
E A
EA
Nikiforov
V A
VA
Saulus
A A
AA
Vasilieva
V F
VF
D000818:Animals; D001834:Body Water / Q000378:metabolism*; D005399:Fishes / Q000378:metabolism*; D007444:Inulin / Q000032:analysis; D007668:Kidney / Q000378:metabolism*; D007687:Kidney Tubules, Proximal / Q000378:metabolism*; D008094:Lithium / Q000097:blood / Q000652:urine*; D012964:Sodium / Q000097:blood / Q000378:metabolism* / Q000652:urine
D007444:Inulin; D008094:Lithium; D012964:Sodium