title: The chromosomal aberrations investigation in children permanently living in the lead polluted area.
abstract: The cytogenetic analysis of peripheral blood lymphocytes in 28 children permanently living in the lead polluted area and in 30 children from the control region was carried out. In the lead exposed group 0-6% of aberrated cells (AB.C.) with the average value of 1.94% of AB.C. were found. The most common findings were represented by the structural aberrations of the chromatid type, in lesser degree also the isochromatid breaks. In the control group 0-3% of AB.C. with average 1.37% was found, which corresponds to the spontaneous level of the chromosomal aberrations 1.2-2% of AB.C. in the unladen population. The differences in the numbers of the aberrated cells between the exposed and control groups are not statistically important. Nevertheless, in the exposed area a certain shift of the AB.C. frequency towards higher values (4.5-6% of AB.C.) is being noticed.
authors: Chair of Social Medicine, Hygiene and Languages.
authors: J
authors: J
authors: Smejkalová
mesh_terms: D000293:Adolescent; D002648:Child; D002869:Chromosome Aberrations; D003604:Czechoslovakia; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D007854:Lead / Q000009:adverse effects* / Q000097:blood; D008297:Male; D012307:Risk Factors
chemical_list: D007854:Lead