[Acute psychiatric syndrome and quinolones].
A case of Flumequine poisoning is described; a 13-year-old girl was admitted for a psychiatric syndrome. 3 hours after, seizures, coma, and metabolic disorders were observed. Infectious, encephalitic or diabetic diseases were suspected, but not confirmed. After 12 hours of a symptomatic treatment, the clinical status improved and the patient was discharged. At that time a tablet was found in her bedroom and a mas spectrographic analysis was positive for Flumequine. This case report is in agreement with previous observations and confirms the small therapeutic index of quinolone, and the absolute necessity to assess carefully a psychiatric diagnosis.
Defoin
J F
JF
SAMU 51/Centre Anti-Poisons-Service du Docteur G.A. SEYS-C.H.R.U. Reims.
Debonne
T
T
Rambourg
M O
MO
Seraphin
J
J
Buffet
M
M
Jaussaud
M
M
Bertault
R
R
Fay
R
R
Digeon
B
B
D000208:Acute Disease; D000293:Adolescent; D003128:Coma / Q000139:chemically induced* / Q000378:metabolism; D005260:Female; D024841:Fluoroquinolones; D006801:Humans; D011807:Quinolizines / Q000506:poisoning*; D012640:Seizures / Q000139:chemically induced* / Q000378:metabolism; D013577:Syndrome
D024841:Fluoroquinolones; D011807:Quinolizines; C012976:flumequine
Syndrome psychiatrique aigu et quinolones.