title: TSH circadian secretions in aged men and effect of phosphatidylserine treatment.
abstract: In 20 euthyroid aged men (from 65 to 85 years of age) no significant circadian periodicity of thyrotropin (TSH) secretion has been shown by the population mean cosinor method. At the end of a period of 30 days of hospitalization the cosinor evaluation of TSH secretion showed a restored highly significant (p less than 0.001) circadian rhythmicity in phosphatidylserine (PS) (400 mg/daily) treated group (10 aged subjects). By contrast, hospitalization seems to further deteriorate the periodicity of the hormone secretion in 10 placebo-treated subjects.
authors: Istituto Scientifico di Medicina Interna, Università di Genova, Italy.
authors: P
authors: P
authors: Masturzo
authors: G
authors: G
authors: Murialdo
authors: D
authors: D
authors: de Palma
authors: U
authors: U
authors: Filippi
authors: D
authors: D
authors: Balbi
authors: M L
authors: ML
authors: Bonura
authors: G
authors: G
authors: Toffano
authors: A
authors: A
authors: Polleri
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002940:Circadian Rhythm / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D008297:Male; D010718:Phosphatidylserines / Q000494:pharmacology*; D013972:Thyrotropin / Q000378:metabolism*; D013973:Thyrotropin-Releasing Hormone / Q000494:pharmacology
chemical_list: D010718:Phosphatidylserines; D013973:Thyrotropin-Releasing Hormone; D013972:Thyrotropin