[Intra-arterial chemotherapy of the liver].
Hepatic artery infusion chemotherapy was introduced to treat non-resectable liver metastases or tumors. Although growth patterns of hepatic metastases and pharmacokinetics of cytostatics are well known, the response rate to intraarterial chemotherapy amounts to a maximum of 50% only, the mean survival time being 1 year or less. Until now, complete healing was not observed. Future efforts should be directed at increasing the response rate, decreasing regional adverse side effects and avoiding extrahepatic disease.
Tuchmann
A
A
I. Chirurgischen Abteilung der Krankenanstalt Rudolfstiftung Wien.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage* / Q000009:adverse effects; D002408:Catheters, Indwelling; D005467:Floxuridine / Q000008:administration & dosage; D005472:Fluorouracil / Q000008:administration & dosage; D006498:Hepatectomy / Q000379:methods; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000601:surgery
D005467:Floxuridine; D005472:Fluorouracil
Intraarterielle Chemotherapie der Leber.