title: Hypersensitivity reaction after orgotein (superoxide dismutase) administration.
abstract: Orgotein is being increasingly used in the treatment of some inflammatory disorders. Up to now no hypersensitivity reaction has been reported. We present the case of an allergic reaction demonstrated by both, "in vivo" and "in vitro" tests. This finding further supports the need for an adequate control during and after orgotein administration.
authors: Allergy Unit, Hospital de Bellvitge Princeps d'Espanya, Barcelona, Spain.
authors: M
authors: M
authors: Corominas
authors: J
authors: J
authors: Bas
authors: A
authors: A
authors: Romeu
authors: A
authors: A
authors: Valls
authors: E
authors: E
authors: Massip
authors: L
authors: L
authors: González
authors: M
authors: M
authors: Mestre
authors: E
authors: E
authors: Buendía
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000627:therapeutic use; D015153:Blotting, Western; D002478:Cells, Cultured; D003875:Drug Eruptions / Q000209:etiology*; D005832:Genital Diseases, Male / Q000209:etiology*; D006801:Humans; D007428:Intradermal Tests; D007963:Leukocytes, Mononuclear / Q000187:drug effects; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D008667:Metalloproteins / Q000009:adverse effects* / Q000627:therapeutic use; D010411:Penile Induration / Q000188:drug therapy*; D013482:Superoxide Dismutase / Q000037:antagonists & inhibitors
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D008667:Metalloproteins; D013482:Superoxide Dismutase; C005180:orgotein