title: [Lymphocyte subpopulations and the soluble interleukin-2 receptor in Hashimoto's thyroiditis and subacute thyroiditis].
abstract: There are no univocal experimental data in literature about T cell clone alterations in the peripheral blood during Hashimoto's thyroiditis (TH), autoimmune disease, and during subacute thyroiditis (TSA), an inflammatory thyroid lesion with possibility of "self-perpetuation". The object of our research was to examine the T cell clones, soluble fraction of interleukin 2 receptor and HLA-DR modifications in patients with TH and TSA compared with healthy population. Our results show significant increase of sIL-2r in the TSA compared with normal subjects and with patients TH, where on the contrary, a constant increase of HLA-DR was observed.
authors: Divisione di Medicina Generale, U.S.L. N. 5, Ospedale Regionale di Campobasso.
authors: A
authors: A
authors: Aiello
authors: M
authors: M
authors: Cristofaro
authors: F
authors: F
authors: Carrozza
authors: F
authors: F
authors: Verdone
authors: L
authors: L
authors: Carile
mesh_terms: D000328:Adult; D005260:Female; D006684:HLA-DR Antigens / Q000032:analysis*; D006801:Humans; D016131:Lymphocyte Subsets; D008297:Male; D008875:Middle Aged; D015375:Receptors, Interleukin-2 / Q000032:analysis*; D013967:Thyroiditis, Autoimmune / Q000097:blood*; D013968:Thyroiditis, Subacute / Q000097:blood*
chemical_list: D006684:HLA-DR Antigens; D015375:Receptors, Interleukin-2
vernacular_title: Studio delle sottopopolazioni linfocitarie e del recettore solubile dell'interleuchina-2 nella tiroidite di Hashimoto e nella tiroidite subacuta.