title: Localisation of acetylcholinesterase in rat myotubes in the presence of beta-endorphin and beta-endorphin-(1-27).
abstract: In rat embryo skeletal myotubes, acetylcholinesterase is present, as multiple forms, and can be detected in deposits at the cell surface. Myotubes cultured in the presence of beta-endorphin, exhibit an increased predominance of the globular (precursor) forms of the enzyme, which are largely restricted to intracellular sites associated with nuclei. In the presence of beta-endorphin-(1-27), the relative proportions of the different forms of acetylcholinesterase is similar to that seen in the controls, but the enzyme is intracellular and has a characteristic focal localisation in the myotube.
authors: Department of Zoology, University of Bristol, England.
authors: L W
authors: LW
authors: Haynes
authors: M E
authors: ME
authors: Smith
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism*; D000818:Animals; D009132:Muscles / Q000201:enzymology*; D010446:Peptide Fragments / Q000378:metabolism*; D051381:Rats; D001615:beta-Endorphin / Q000378:metabolism*
chemical_list: D010446:Peptide Fragments; D001615:beta-Endorphin; C035581:beta-endorphin (1-27); D000110:Acetylcholinesterase