Repeated dialysis anaphylaxia.
A 76-year-old woman with multiple allergic reactions was treated 17 times by haemodialysis. Symptoms of anaphylactoid reactions of increasing severity led to final death due to cardiorespiratory arrest. Anaphylactoid reactions appeared 5-30 min after the start of dialysis and lasted for 15-20 min. They first occurred on the 7th dialysis and consisted of hypotension, diarrhoea, bronchospasm, bradycardia and respiratory arrest. Change of dialysis regime, dialyser (gamma-sterilised, autoclaved), heparin, and administration of antihistamines, steroid, and adrenaline did not prevent these reactions.
Wenzel-Seifert
K
K
Department of Internal Medicine, Universitätsklinikum Steglitz, Berlin, FRG.
Sharma
A M
AM
Keller
F
F
D000368:Aged; D000707:Anaphylaxis / Q000209:etiology*; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy; D007688:Kidneys, Artificial; D006435:Renal Dialysis / Q000009:adverse effects* / Q000401:mortality