Contact dermatitis caused by intermediate products in the manufacture of clenbuterol, ranitidine base, and ranitidine hydrochloride.
Clenbuterol, a beta antagonist, and ranitidine, a histamine-receptor antagonist, were associated with contact dermatitis in a chemist. The allergen in the former was an intermediate in the synthesis called beta. In the latter, intermediates and the finished base and hydrochloride were responsible.
Romaguera
C
C
Catédra y Escuela Profesional de Dermatología y Venereología, Facultad de Medicina, Universidad Central de Barcelona, Spain.
Grimalt
F
F
Vilaplana
J
J
D000328:Adult; D002976:Clenbuterol / Q000009:adverse effects* / Q000138:chemical synthesis; D003877:Dermatitis, Contact / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000139:chemically induced*; D004983:Ethanolamines / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010328:Patch Tests; D011899:Ranitidine / Q000009:adverse effects* / Q000138:chemical synthesis
D004983:Ethanolamines; D011899:Ranitidine; D002976:Clenbuterol