Nephrotic syndrome in two members of a family with mercury poisoning.
Elevated urine mercury levels in two Asian brothers with the nephrotic syndrome led to the discovery of very high mercury concentrations in 7 out of 10 other family members. Mercury contamination was caused by gold refining in a garage at the home. Although childhood nephrotic syndrome is usually idiopathic, the proteinuria and the mercury inhalation were probably causally related in this family.
Meeks
A
A
Department of Child Health, University of Leicester, United Kingdom.
Keith
P R
PR
Tanner
M S
MS
D002675:Child, Preschool; D006798:Housing; D006801:Humans; D008297:Male; D008628:Mercury / Q000032:analysis; D008630:Mercury Poisoning / Q000150:complications*; D009404:Nephrotic Syndrome / Q000139:chemically induced* / Q000188:drug therapy / Q000652:urine; D011239:Prednisolone / Q000627:therapeutic use; D011507:Proteinuria / Q000188:drug therapy / Q000652:urine
D011239:Prednisolone; D008628:Mercury