title: [Drug resistance and various selected demographic and clinical characteristics of patients with endogenous depression].
abstract: The influence of some selected demographic and clinical characteristics on the formation of resistance to antidepressant drugs were studied in the group of 115 patients with affective disorders. Drug resistance occurs as frequently in women as in men. It appears much frequently in patients after 40 (about 30%). Persons under 30 are not or very rarely affected. Type I of bipolar affective disorder and the occurrence of affective disorder in relatives are positive prognostic factors. The long relapses (greater than 20 weeks) are of the worse prognostic value than shorter ones (less than 3 months). Previous poor efficiency of antidepressant drugs predicts very often an identical response during current episode. Alcohol abuse is an unfavourable prognostic factor in men with endogenous depression.
authors: II Kliniki Psychiatrycznej Instytutu Psychiatrii i Neurologii w Warszawie.
authors: S
authors: S
authors: Puzyński
authors: A
authors: A
authors: Kalinowski
authors: E
authors: E
authors: Bidzińska
authors: M
authors: M
authors: Beresewicz
mesh_terms: D000328:Adult; D000367:Age Factors; D000437:Alcoholism / Q000150:complications / Q000523:psychology; D000928:Antidepressive Agents / Q000627:therapeutic use*; D001714:Bipolar Disorder / Q000188:drug therapy*; D003866:Depressive Disorder / Q000150:complications / Q000188:drug therapy*; D004351:Drug Resistance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis
chemical_list: D000928:Antidepressive Agents
vernacular_title: Zjawisko lekooporności a wybrane cechy demograficzne i kliniczne chorych z depresja endogenna.