[Male sterility and reciprocal translocation (4;15). Description of a case].
Chromosome abnormalities in infertile males are not infrequent, ranging from 4% to about 1% for sex and autosomal chromosomes respectively. Autosomal abnormalities mainly consist of balanced translocations, mostly robertsonian. The Authors report a case of reciprocal translocation t (4;15) associated with oligozoospermia and sterility in a 37 years-old man. The break-points involved in the translocation (4q25; 15p11) seem to be quite uncommon. The possible relationship between this unusual translocation and sterility is discussed.
Piovani
G
G
Istituto di Clinica Medica e Nefrologia, Università degli Studi di Parma.
Zanelli
P
P
Neri
T M
TM
Savi
M
M
D000328:Adult; D002871:Chromosome Banding; D002884:Chromosomes, Human, Pair 15; D002894:Chromosomes, Human, Pair 4; D006801:Humans; D007248:Infertility, Male / Q000235:genetics*; D007621:Karyotyping; D008297:Male; D008677:Metaphase; D014178:Translocation, Genetic
Sterilità maschile e traslocazione reciproca t (4;15). Descrizione di un caso.