[Osteoporosis in a man with idiopathic hypercalciuria, renal variety, treated with a hypocalcic diet].
A 61 year old man with a calcic urinary stone at age 46 was submitted to a prolonged low calcium diet (about 400 mg/day). Normal serum calcium and elevated urinary Ca (725 mg/day were demonstrated). After a diet with a normal Ca content (900 mg/day) urinary excretion did not change. PTH, serum Ca and P were normal. Biphoton bone densitometry revealed severe osteopenia, with a spine density of 51% of normal. The addition of hydrocortisone (50 mg/day) reduced urinary Ca output over 25%; the addition of phosphate, 1125 mg/day, brought Ca output to normal levels. Thus, prolonged dietary restriction of Ca in the presence of high urinary Ca loss may produce severe osteopenia and osteoporosis.
Pumarino
H
H
Departamento de Medicina, Hospital Clínico José Joaquín Aguirre, Facultad de Medicina, Universidad de Chile, Santiago.
D002118:Calcium / Q000097:blood / Q000652:urine; D002136:Calcium, Dietary / Q000008:administration & dosage*; D006801:Humans; D006934:Hypercalcemia / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000000981:diagnostic imaging / Q000178:diet therapy / Q000209:etiology*; D010281:Parathyroid Hormone / Q000032:analysis; D011859:Radiography; D014545:Urinary Calculi / Q000178:diet therapy*
D002136:Calcium, Dietary; D010281:Parathyroid Hormone; D002118:Calcium
Osteoporosis en un hombre con hipercalciuria idiopática, variedad renal, sometido a dieta hipocálcica.