title: [Chorionic villi sampling: experience of the initial 500 samples].
abstract: We report our experience in first trimester antenatal diagnosis since 1984. Transcervical chorionic villus sampling (CVS) was performed in 498 pregnancies. The rate of abnormal pregnancies was 6%, the rate of chromosomal abnormalities (trisomy) in the indication group "maternal age" was 2%. The fetal loss rate (until 28 weeks) was 3.4% (17 cases), the procedure related loss plus the background loss was 2.4% (12 cases). For 92.8% of the patients a diagnosis was available after 1 CVS procedure. Ultimately an antenatal diagnosis was given to 99% of the women through a second CVS procedure or an amniocentesis or a cordocentesis. No maternal complication was observed.
authors: Laboratoire de cytogénétique, Hôpital Universitaire Brugmann.
authors: C
authors: C
authors: Donner
authors: P
authors: P
authors: Simon
authors: F
authors: F
authors: Gosselin
authors: E
authors: E
authors: Vamos
authors: P
authors: P
authors: Cochaux
authors: G
authors: G
authors: Vassart
authors: F
authors: F
authors: Rodesch
mesh_terms: D015193:Chorionic Villi Sampling; D002869:Chromosome Aberrations / Q000175:diagnosis*; D025063:Chromosome Disorders; D004314:Down Syndrome / Q000175:diagnosis* / Q000235:genetics; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D011247:Pregnancy; D014314:Trisomy
vernacular_title: La choriocentèse: expérience des 500 premiers prélèvements.