title: Isolation and characterization of a high molecular weight lymphocyte Fc gamma receptor-blocking factor associated with renal allograft survival.
abstract: We have confirmed our previous observation that improved human renal allograft survival is associated with the presence in pre-transplant serum of a high molecular weight lymphocyte Fc gamma receptor-blocking factor. Serum fractionation studies suggest that this factor is a complex protein consisting of IgG together with an IgG-binding protein which has an apparent molecular weight of approximately 60 kD.
authors: University Department of Pathology, Western Infirmary, Glasgow, Scotland.
authors: G P
authors: GP
authors: Sandilands
authors: J E
authors: JE
authors: Cocker
authors: M A
authors: MA
authors: McMillan
authors: A M
authors: AM
authors: Owsianka
authors: H
authors: H
authors: Marsden
authors: B J
authors: BJ
authors: Junor
authors: J D
authors: JD
authors: Briggs
authors: R N
authors: RN
authors: MacSween
mesh_terms: D000943:Antigens, Differentiation / Q000276:immunology*; D001685:Biological Factors / Q000276:immunology* / Q000302:isolation & purification; D002499:Centrifugation, Density Gradient; D002852:Chromatography, Ion Exchange; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006085:Graft Survival / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology / Q000302:isolation & purification; D016030:Kidney Transplantation / Q000276:immunology*; D008222:Lymphokines / Q000276:immunology / Q000302:isolation & purification; D008297:Male; D008970:Molecular Weight; D029584:Prostatic Secretory Proteins; D011961:Receptors, Fc / Q000276:immunology*; D017452:Receptors, IgG; D012397:Rosette Formation
chemical_list: D000943:Antigens, Differentiation; D001685:Biological Factors; D007074:Immunoglobulin G; D008222:Lymphokines; D029584:Prostatic Secretory Proteins; D011961:Receptors, Fc; D017452:Receptors, IgG; C043076:beta-microseminoprotein; C013059:immunoglobulin-binding factors