title: [New route of 2-N-(carboxypropylamino)-2-deoxy-D-glucopyranose synthesis].
abstract: A new route to 2-N-(carboxypropylamino)-2-deoxy-D-glucopyranose synthesis is reported, involving the Schiff-base derivative of beta-D-glucosamine with benzyl 4-oxobutyrate. Improvement in the synthesis of benzyl-4-oxobutyrate is also described. Biological compounds action was investigated by evaluating sedative and dopaminergic activities on male mice.
authors: Laboratoire de Chimie des Médiateurs Moléculaires, Université Pierre et Marie Curie, Paris.
authors: R
authors: R
authors: Couffignal
authors: F
authors: F
authors: Dardoize
authors: C
authors: C
authors: Goasdoue
authors: N
authors: N
authors: Goasdoue
authors: H M
authors: HM
authors: Laborit
authors: G
authors: G
authors: Topall
mesh_terms: D000818:Animals; D003847:Deoxyglucose / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D018492:Dopamine Antagonists; D006993:Hypnotics and Sedatives / Q000037:antagonists & inhibitors; D008297:Male; D051379:Mice; D005680:gamma-Aminobutyric Acid / Q000031:analogs & derivatives*
chemical_list: D018492:Dopamine Antagonists; D006993:Hypnotics and Sedatives; C071453:2-N-(carboxypropylamino)-2-deoxyglucopyranose; D005680:gamma-Aminobutyric Acid; D003847:Deoxyglucose
vernacular_title: Nouvelle voie de synthèse de 2-N-(carboxypropylamino)-2-désoxy-D-glucopyranose.