An 8-year experience with depth electrodes in the evaluation of ablative seizure surgery candidates.
Stereotactically implanted depth electrodes are one means of localization of seizure foci. Unilateral seizure focus localization was obtained in 72.7% mesial temporal (MT) implants and 50% of focus/extramesial temporal (MT-XMT) implants. Recent increase in localization to over 80% in MT implants was possible because a larger percentage of patients had MT-XMT implants. Increased localization to 60% in MT-XMT implants was related to using more XMT electrodes per patient and to orienting electrodes to monitor larger limbic XMT and neocortical areas. Since MT foci were localized in 25% of MT-XMT cases, MT electrodes should be included with all MT-XMT implants. Depth electrography can also be used to rule out certain patients as surgical candidates. Therefore, a surgical decision can be reached in a very high percentage of patients undergoing depth implantation. Surgical results are comparable to those in our overall series.
Smith
J R
JR
Division of Neurosurgery, Medical College of Georgia, Augusta.
Flanigin
H F
HF
King
D W
DW
Gallagher
B B
BB
Murro
A M
AM
Holmes
G L
GL
Campbell
L R
LR
Lee
G
G
Wheless
J
J
D001931:Brain Mapping / Q000295:instrumentation; D004292:Dominance, Cerebral / Q000502:physiology; D004567:Electrodes, Implanted; D004569:Electroencephalography / Q000295:instrumentation*; D004828:Epilepsies, Partial / Q000503:physiopathology / Q000601:surgery*; D004833:Epilepsy, Temporal Lobe / Q000503:physiopathology / Q000601:surgery*; D005071:Evoked Potentials / Q000502:physiology; D006801:Humans; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation; D013238:Stereotaxic Techniques / Q000295:instrumentation*; D013702:Temporal Lobe / Q000503:physiopathology / Q000601:surgery