title: Fibre-laser IR luminescence diagnostics of malignant tumours using rare earth porphyrins.
abstract: To eliminate the masking effect of the background luminescence of endogenic substances in biological tissues and to increase the luminescence contrast values of malignant tumours, sarcoma-implanted mice were administered with ytterbium porphyrins instead of free porphyrin radicals. This was followed by in vivo luminescence localization of tumours using fibre-laser spectrofluorometry. The luminescence contrast values obtained reached 10-45 which is evidently not a limit.
authors: Institute of Radio Engineering and Electronics, U.S.S.R. Academy of Sciences, Moscow.
authors: M I
authors: MI
authors: Gaiduk
authors: V V
authors: VV
authors: Grigoryants
authors: A F
authors: AF
authors: Mironov
authors: V D
authors: VD
authors: Rumyantseva
authors: V I
authors: VI
authors: Chissov
authors: G M
authors: GM
authors: Sukhin
mesh_terms: D000818:Animals; D008163:Luminescent Measurements; D051379:Mice; D008810:Mice, Inbred C57BL; D011166:Porphyrins / Q000493:pharmacokinetics; D012513:Sarcoma, Experimental / Q000175:diagnosis* / Q000378:metabolism; D013050:Spectrometry, Fluorescence; D013055:Spectrophotometry, Infrared; D015018:Ytterbium
chemical_list: D011166:Porphyrins; D015018:Ytterbium