title: [Generalized persistent lymphadenopathy syndrome in parenteral drug addicts. Lymph node biopsy study of 41 patients].
abstract: Of a total of 41 VIH positive patients, parenteral drug addicts, with persistent generalized lymphadenopathy syndrome, we performed 43 lymph-node biopsies. In two sequential biopsies, 2 and 12 months respectively after the first biopsy, were carried-out. After a clinical follow-up (ranging between 4-28 months) 12 patients (24.3%) were qualified as SIDA cases according to CDC-1987 criteria. Lymph-node biopsy was of diagnostic or prognostic value in 16.27% and in 6.97% respectively. Upon comparing histological types and peripheral lymphocyte subsets it was demonstrated how the forms of major morphological deterioration tend to associate with a lower number of OKT4+ lymphocytes and a lower relation OKT4+/OKT8+.
authors: Departamento de Medicina, Hospital Clínico Universitario, Valencia.
authors: G
authors: G
authors: Vera-Sempere
authors: F J
authors: FJ
authors: Vera-Sempere
authors: J
authors: J
authors: Guix-García
mesh_terms: D000386:AIDS-Related Complex / Q000209:etiology / Q000473:pathology*; D000328:Adult; D001706:Biopsy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007958:Leukocyte Count; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D015819:Substance Abuse, Intravenous / Q000150:complications*; D019966:Substance-Related Disorders / Q000150:complications*; D013601:T-Lymphocytes
vernacular_title: Síndrome de la linfoadenopatía persistente generalizada en adictos a drogas por vía parenteral. Estudio biópsico ganglionar de 41 pacientes.