Mutations in bglY, the structural gene for the DNA-binding protein H1, affect expression of several Escherichia coli genes.
The protein patterns of a bglY mutant and the isogenic wild-type strains were compared on 2-dimensional gel electrophoresis. The synthesis of at least 36 peptides was affected. This suggests a global but specific role on gene expression for the DNA-binding protein H1.
Bertin
P
P
Unité de Régulation de l'Expression Génétique, Université de Louvain, Louvain-la-Neuve, Belgium.
Lejeune
P
P
Laurent-Winter
C
C
Danchin
A
A
D001426:Bacterial Proteins / Q000235:genetics* / Q000302:isolation & purification; D004268:DNA-Binding Proteins / Q000235:genetics* / Q000302:isolation & purification; D015180:Electrophoresis, Gel, Two-Dimensional; D004926:Escherichia coli / Q000235:genetics*; D015964:Gene Expression Regulation, Bacterial; D005796:Genes; D005798:Genes, Bacterial; D009154:Mutation
D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; C031908:H-NS protein, bacteria