The pathogenesis of HIV infection.
With HIV infection, a struggle between virus and host begins. Even though the eventual outcome seems predetermined, in most patients HIV may remain relatively nonpathogenic as long as the immune system can suppress it. A key question is whether host antiviral activity eventually breaks down or whether the virus mutates into strains that can destroy the immune system.
Levy
J A
JA
Department of Medicine, University of California School of Medicine, San Francisco.
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000209:etiology* / Q000276:immunology / Q000382:microbiology / Q000635:transmission; D004279:DNA, Viral / Q000032:analysis; D006678:HIV / Q000145:classification / Q000235:genetics / Q000378:metabolism / Q000472:pathogenicity* / Q000648:ultrastructure; D006801:Humans; D007111:Immunity, Cellular; D050378:T-Lymphocytes, Regulatory / Q000276:immunology / Q000502:physiology; D013997:Time Factors; D014779:Virus Replication / Q000502:physiology
D004279:DNA, Viral