Serotonin-specific drugs for anxiety and depressive disorders.
In the last few years there has been a marked increase in knowledge regarding the possible roles of serotonin neuronal dysfunction in the pathophysiology and treatment of anxiety and depressive disorders. During the same time period, new drugs with specific actions on serotonin function have become available for clinical testing. This review provides an update on the efficacy of serotonin-specific drugs for anxiety and depressive disorders.
Charney
D S
DS
Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06510.
Krystal
J H
JH
Delgado
P L
PL
Heninger
G R
GR
D001008:Anxiety Disorders / Q000188:drug therapy*; D003866:Depressive Disorder / Q000188:drug therapy*; D006801:Humans; D014179:Neurotransmitter Uptake Inhibitors / Q000627:therapeutic use*; D011985:Receptors, Serotonin / Q000187:drug effects*; D012701:Serotonin / Q000502:physiology*; D012702:Serotonin Antagonists / Q000627:therapeutic use*
D014179:Neurotransmitter Uptake Inhibitors; D011985:Receptors, Serotonin; D012702:Serotonin Antagonists; D012701:Serotonin