[Effect of jia wei yubingfengsan on bacterial adhesion to mouse tracheain chronic bronchitis model].
The experiment was designed to test the effect of Jia Wei Yubingfengsan (JW-YBFS) in chronic bronchitis of mice model. Two groups of mice model was used, one of which received JW-YBFS by oral administration another received only water as control experiment. The accurate quantification of bacterial adhesiveness by culture method showed that in JW-YBFS receiving mice viable counts of bacteria is much less than the control mice. In addition pathological examination showing the injury of tracheate mucosal epithelium was not found in JW-YBFS receiving mice while control mice showing typical chronic bronchitis lesion. The results demonstrated that JW-YBFS plays significantly role in bronchitis mice model. Our experimental data are in good agreement with Chinese medical conclusion, which means Fu Zheng Gu Ben.
Kong
F Z
FZ
Zhejiang Academy of Traditional Chinese Medicine.
D000818:Animals; D001422:Bacterial Adhesion / Q000187:drug effects*; D001991:Bronchitis / Q000188:drug therapy* / Q000382:microbiology; D002908:Chronic Disease; D004365:Drugs, Chinese Herbal / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D008297:Male; D051379:Mice; D009092:Mucous Membrane / Q000648:ultrastructure; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D051381:Rats; D011919:Rats, Inbred Strains; D014132:Trachea / Q000382:microbiology* / Q000648:ultrastructure
D004365:Drugs, Chinese Herbal