In situ mapping of the muscle-specific form of phosphoglycerate mutase gene to human chromosome 7p12-7p13.
A 2.3-kb-long probe derived from the 5' flanking region, the first exon and part of the first intron of the human muscle-specific phosphoglycerate mutase gene (PGAM-M) (EC 5.4.2.1) was used to map the gene by "in situ" chromosomal hybridization. The structural gene for PGAM-M was assigned to chromosome 7p12-7p13; a single hybridization peak indicated that there is a single gene for this isozyme of PGAM, and confirmed results obtained by Southern blot hybridization.
Castella-Escola
J
J
Unité INSERM U91, Hôpital Henri Mondor, Créteil, France.
Mattei
M G
MG
Ojcius
D M
DM
Passage
E
E
Valentin
C
C
Cohen-Solal
M
M
D001731:Bisphosphoglycerate Mutase / Q000235:genetics*; D015139:Blotting, Southern; D002871:Chromosome Banding; D002897:Chromosomes, Human, Pair 7; D006801:Humans; D007527:Isoenzymes / Q000235:genetics; D007621:Karyotyping; D009132:Muscles / Q000201:enzymology*; D010770:Phosphotransferases / Q000235:genetics*; D015183:Restriction Mapping
D007527:Isoenzymes; D010770:Phosphotransferases; D001731:Bisphosphoglycerate Mutase