Effect of taurine supplements on growth, fat absorption and bile acid on cystic fibrosis.
We have evaluated the effect of taurine supplementation nutritional status, steatorrhea and bile acid in twenty two Cystic Fibrosis patients. Weight increased in fifty per cent and height in forty eight per cent of them. Steatorrhea improved significantly in six patients of group II. Glycine/taurine ratio was reduced. Bile acid malabsorption improved only in the patients with high degree of steatorrhea. Serum bile acid was observed significantly elevated in both groups. This results suggest that taurine supplementation can be useful adjunct from of therapy in Cystic Fibrosis patients with fat malabsorption.
Carrasco
S
S
Department of Pediatrics, Children's Hospital La Paz, Autonoma University, Madrid, Spain.
Codoceo
R
R
Prieto
G
G
Lama
R
R
Polanco
I
I
D000293:Adolescent; D000328:Adult; D001647:Bile Acids and Salts / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D004041:Dietary Fats / Q000493:pharmacokinetics; D005260:Female; D006128:Growth / Q000187:drug effects; D006801:Humans; D007223:Infant; D008297:Male; D013654:Taurine / Q000627:therapeutic use*
D001647:Bile Acids and Salts; D004041:Dietary Fats; D013654:Taurine