title: Effect of diet on struvite activity product in feline urine.
abstract: Groups of male specific-pathogen-free cats were fed a basal, purified diet (A), with or without 0.45% added magnesium (MgCl2, diet B; MgO, diet C) or 1 of 2 commercial diets (D,E). Urine samples collected for 48 hours after 2 weeks of feeding were analyzed for calcium, magnesium, sodium, potassium, ammonium, sulfate, phosphate, oxalate, and citrate content. Concentrations were used to calculate the negative logarithm of the struvite activity product (pSAP), using a microcomputer-based program for calculation of supersaturation of the urine with crystal solutes. The pSAP value for all samples also was hand-calculated by use of an equation. Consumption of diet B caused a significant (P less than 0.05) increase in urine calcium concentration. Total urine phosphate concentration was lower in urine from cats fed diets A, B, or C than in urine from cats fed diets D or E. For the various diets, urine PO4(-3) was: 5.3 microM for diet A; 6.3 microM for diet C; 0.9 microM for diet E; 36 nM for diet D, and 0.5 nM for diet B. Consumption of diets B and C caused significant increases in urine magnesium concentration (53.1 nM and 49.1 mM, respectively). Ammonium ion concentration was highest in urine from cats fed diets B and D, 116.2 mM and 100.3 mM, respectively. When the pSAP, hand-calculated assuming ionic strength u = 0.2, was regressed on that calculated by use of the microcomputer program, the coefficient of determination was 0.96 (P less than or equal to 0.01).
authors: Department of Physiological Sciences, College of Veterinary Medicine, University of California, Davis 95616.
authors: C A
authors: CA
authors: Buffington
authors: Q R
authors: QR
authors: Rogers
authors: J G
authors: JG
authors: Morris
mesh_terms: D000818:Animals; D002118:Calcium / Q000652:urine; D002415:Cats / Q000652:urine*; D005526:Food, Formulated; D008274:Magnesium / Q000652:urine*; D017616:Magnesium Compounds; D008275:Magnesium Deficiency / Q000662:veterinary; D008277:Magnesium Oxide / Q000652:urine; D008297:Male; D010710:Phosphates / Q000652:urine*; D012964:Sodium / Q000652:urine; D013047:Specific Pathogen-Free Organisms; D000069877:Struvite
chemical_list: D017616:Magnesium Compounds; D010710:Phosphates; D008277:Magnesium Oxide; D012964:Sodium; D000069877:Struvite; D008274:Magnesium; D002118:Calcium