title: Cloning of the mouse homologue of the yeast cell cycle control gene cdc2.
abstract: The cdc2 cell cycle control genes of yeast and man encode 34 kDa protein kinases. Using the human CDC2 gene as a DNA probe we have isolated cDNA clones corresponding to the mouse cdc2 gene. Sequencing of the mouse clones show 96% identity at the amino acid level to the human CDC2 gene and detects a 2 kb RNA product indistinguishable to that seen in human cells. The mouse gene should be useful in studying the functional control of the cell cycle in mouse cells.
authors: Imperial Cancer Research Fund, Clare Hall Laboratories, Blanche Lane, Potters Bar, UK.
authors: N K
authors: NK
authors: Spurr
authors: A C
authors: AC
authors: Gough
authors: M G
authors: MG
authors: Lee
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015152:Blotting, Northern; D015139:Blotting, Southern; D016203:CDC2 Protein Kinase / Q000235:genetics*; D003001:Cloning, Molecular; D004247:DNA; D006801:Humans; D051379:Mice; D008969:Molecular Sequence Data; D012568:Schizosaccharomyces / Q000235:genetics; D016415:Sequence Alignment; D012689:Sequence Homology, Nucleic Acid
chemical_list: D004247:DNA; D016203:CDC2 Protein Kinase