[Antihypertensive treatment: a combination of delapril, a new ACE-inhibitor, and indapamide].
The controlled study was carried out on 15 patients with essential hypertension not sufficiently controlled after one month of monotherapy with an ACE-inhibitor. To the above therapy was therefore associated a low dosage diuretic (indapamide 2.5 mg/day). The observation period was of 12 weeks. The delapril-indapamide combination was found to be very effective in reducing blood pressure values; no significant metabolic adverse effects were observed.
Coruzzi
P
P
Università degli Studi di Parma, Istituto di Semeiotica Medica.
Ravanetti
C
C
Alberici
M
M
Novarini
A
A
D000328:Adult; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D004232:Diuretics / Q000627:therapeutic use*; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy*; D007189:Indans / Q000627:therapeutic use*; D007190:Indapamide / Q000627:therapeutic use*; D007192:Indenes / Q000627:therapeutic use*; D008297:Male
D000806:Angiotensin-Converting Enzyme Inhibitors; D004232:Diuretics; D007189:Indans; D007192:Indenes; D007190:Indapamide; C047759:delapril
Terapia antipertensiva: associazione tra delapril, nuovo ACE-inibitore, ed indapamide.