[Detection of specific IgG and its specific circular immune complex in the diagnosis of tuberculosis].
In order to search for the immunological diagnostic methods of pulmonary tuberculosis, extrapulmonary tuberculosis and its autoimmunopathy, we determined the PPD-C IgG and PPD-C IgG present in CIC by means of PPD-C-based ELISA in 50 tuberculosis patients, 20 patients with lung cancer and 30 normal subjects. The positive rates of serum PPD-C IgG in tuberculosis, lung cancer and normal subjects were 62%, 5% and 6.7% respectively. The positive rates of PPD-C IgG present in CIC were 86%, 10% and 6.7% respectively. The sensitivity of PPD-C IgG present in CIC was 86% and the specificity was 92%. It was suggested that CIC surface PPD-C IgG was more valuable in the diagnosis of tuberculosis.
Yang
P Z
PZ
Bethune International Peace Hospital of PLA, Shi jiazhuang.
D000907:Antibodies, Bacterial / Q000097:blood*; D000936:Antigen-Antibody Complex / Q000097:blood*; D003176:Complement C3 / Q000032:analysis; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D009169:Mycobacterium tuberculosis / Q000276:immunology*; D014373:Tuberculin / Q000276:immunology; D014396:Tuberculosis, Pleural / Q000175:diagnosis; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000276:immunology
D000907:Antibodies, Bacterial; D000936:Antigen-Antibody Complex; D003176:Complement C3; D007074:Immunoglobulin G; D014373:Tuberculin