Antagonism by the diacylglycerol kinase inhibitor R59 022 of muscarinic receptor-mediated cyclic GMP formation and binding of [3H]N-methylscopolamine.
Lai
W S
WS
Department of Pharmacology and Toxicology, University of Maryland, School of Pharmacy, Baltimore 21201.
el-Fakahany
E E
EE
D000818:Animals; D001667:Binding, Competitive; D002217:Carbachol / Q000494:pharmacology; D006152:Cyclic GMP / Q000096:biosynthesis*; D019852:Diacylglycerol Kinase; D051379:Mice; D018727:Muscarinic Antagonists; D019832:N-Methylscopolamine; D010770:Phosphotransferases / Q000037:antagonists & inhibitors*; D011744:Pyrimidinones / Q000494:pharmacology*; D011976:Receptors, Muscarinic / Q000502:physiology; D012602:Scopolamine Derivatives / Q000378:metabolism*; D013844:Thiazoles / Q000494:pharmacology*; D014407:Tumor Cells, Cultured
D018727:Muscarinic Antagonists; D011744:Pyrimidinones; D011976:Receptors, Muscarinic; D012602:Scopolamine Derivatives; D013844:Thiazoles; D002217:Carbachol; C047505:R 59022; D010770:Phosphotransferases; D019852:Diacylglycerol Kinase; D006152:Cyclic GMP; D019832:N-Methylscopolamine