[Activation of Fc gamma receptor (CD16) positive natural killer cells by rheumatoid factors in rheumatoid arthritis].
Fc gamma-receptor-(CD16-)positive natural killer (NK) cells are activated by rheumatoid factor in the synovial fluid of patients with rheumatoid arthritis. This activation induces modulation of the CD16 molecule and release of IFN gamma and TNF alpha by NK cells.
Kuipers
J G
JG
Medizinische Hochschule Hannover, Abteilung Immunologie und Transfusionsmedizin.
Hendrich
C
C
Kolanus
W
W
Hammer
M
M
Schmidt
R E
RE
D015703:Antigens, CD / Q000276:immunology*; D000943:Antigens, Differentiation / Q000276:immunology*; D001172:Arthritis, Rheumatoid / Q000276:immunology*; D002846:Chromatography, Affinity; D006801:Humans; D007371:Interferon-gamma / Q000096:biosynthesis; D007694:Killer Cells, Natural / Q000276:immunology*; D007958:Leukocyte Count; D008213:Lymphocyte Activation; D011961:Receptors, Fc / Q000276:immunology*; D017452:Receptors, IgG; D012217:Rheumatoid Factor / Q000276:immunology*; D013582:Synovial Fluid / Q000276:immunology; D014409:Tumor Necrosis Factor-alpha / Q000096:biosynthesis
D015703:Antigens, CD; D000943:Antigens, Differentiation; D011961:Receptors, Fc; D017452:Receptors, IgG; D014409:Tumor Necrosis Factor-alpha; D007371:Interferon-gamma; D012217:Rheumatoid Factor
Aktivierung von Fc gamma-Rezeptor-(CD16-)positiven natürlichen Killerzellen durch Rheumafaktoren im Rahmen der rheumatoiden Arthritis.