title: [Studies of rapid detection of drug-resistance of Mycobacterium by gas chromatography].
abstract: This test is based on the physiologic character of mycobacterium, which produces carbon dioxide (CO2) during its growth, Löwenstein-Jensen media CO2 contents-were measured by gas chromatography for determining drug-resistance of mycobacteria. This was compared with the routine method. Seventy-eight mycobacteria were isolated from suspected tuberculosis patients for the experiment. Our data suggested that the accordance rates of both methods were 83.3%. Gas chromatography is a simple, rapid and accurate method for detecting drug-resistance. The results can be obtained twenty days earlier than by the routine method.
authors: Department of Internal Medicine, Sichuan University.
authors: Z
authors: Z
authors: He
authors: J
authors: J
authors: Li
authors: S
authors: S
authors: Zhao
authors: S
authors: S
authors: Ding
authors: L
authors: L
authors: Wu
authors: Q
authors: Q
authors: Zhao
mesh_terms: D000995:Antitubercular Agents / Q000494:pharmacology*; D002245:Carbon Dioxide / Q000032:analysis; D002849:Chromatography, Gas; D004352:Drug Resistance, Microbial; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000187:drug effects*
chemical_list: D000995:Antitubercular Agents; D002245:Carbon Dioxide