[Protection of an oral vaccine against experimental infection of mice and its role combined with the administration of penicillin].
The AA. studied the immunologic profile of an oral vaccine to prevent the experimental infection in mice and its effect when it was administered with antibiotic. The mice were infected with Staphylococcus aureus and protected by the vaccine administration. Our results confirmed the higher survival in the group that used this combination. The observed mortality was lower in group of mice treated with vaccine and penicillin combination, than in the untreated group.
Gismondo
M R
MR
Istituto di Microbiologia, Università di Catania.
Lo Bue
A M
AM
Chisari
G
G
Stivala
F
F
D000284:Administration, Oral; D000818:Animals; D000942:Antigens, Bacterial / Q000008:administration & dosage; D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D008297:Male; D051379:Mice; D010406:Penicillins / Q000008:administration & dosage / Q000627:therapeutic use*; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000628:therapy*
D000942:Antigens, Bacterial; D001428:Bacterial Vaccines; D010406:Penicillins
Difesa di un vaccino orale dall'infezione sperimentale nel topo e suo ruolo combinato con la somministrazione di penicillina.