Methotrexate sensitivity in Down's syndrome: a hypothesis.
Ueland
P M
PM
Department of Pharmacology and Toxicology, University of Bergen, Norway.
Refsum
H
H
Christensen
B
B
D004314:Down Syndrome / Q000150:complications* / Q000378:metabolism; D004361:Drug Tolerance; D005493:Folic Acid Antagonists; D006710:Homocysteine / Q000378:metabolism; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000188:drug therapy*
D005493:Folic Acid Antagonists; D006710:Homocysteine; D008727:Methotrexate