[Photosensitivity following enoxacin and xipamide: combined phototoxic and photo-allergic reaction to enoxacin, photo-allergic reaction to xipamide with subsequent transient light reaction].
In a 51-year-old female patient, we observed a combined phototoxic and photoallergic reaction to Enoxacin, a photoallergic reaction to Xipamide, as well as increased sensitivity to light after withdrawal of the drugs. This unusual diagnosis was based on the clinical picture, graded radiation with UV-A and UV-B, the irradiated intradermal assay, and histological findings. To the best of our knowledge, this is the first report on a photoallergic reaction to Xipamide associated with a combined phototoxic and photoallergic reaction to Enoxacin.
Schauder
S
S
Abteilung Dermato-Venerologie I, Georg-August-Universität Göttingen.
D001706:Biopsy; D001991:Bronchitis / Q000188:drug therapy*; D004232:Diuretics / Q000009:adverse effects*; D003875:Drug Eruptions / Q000473:pathology*; D004359:Drug Therapy, Combination; D015365:Enoxacin / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007428:Intradermal Tests / Q000379:methods; D008875:Middle Aged; D010328:Patch Tests / Q000379:methods; D010787:Photosensitivity Disorders / Q000139:chemically induced*; D012867:Skin / Q000473:pathology; D014466:Ultraviolet Rays; D014988:Xipamide / Q000008:administration & dosage / Q000009:adverse effects*
D004232:Diuretics; D015365:Enoxacin; D014988:Xipamide
Photosensitivität nach Enoxacin und Xipamid: Kombinierte phototoxische und photoallergische Reaktion auf Enoxacin, photoallergische Reaktion auf Xipamid mit nachfolgender transienter Lichtreaktion.