Contact allergy to furazolidone.
A case of occupational contact allergy to furazolidone, used as an animal feed additive and as an antimicrobial drug in veterinary medicine, is described. The patient did not react to furazolidone 2% pet. Using PEG-400 and alcohol as patch test vehicles resulted in positive patch test reactions. No cross-reactions were observed to other nitrofuran derivatives (nitrofurazone, nitrofurantoin) or to furfural. The literature on contact allergy to nitrofurans is reviewed.
de Groot
A C
AC
Department of Dermatology, Carolus Hospital, BD's-Hertogenbosch, The Netherlands.
Conemans
J M
JM
D000328:Adult; D000821:Animal Feed / Q000009:adverse effects; D003877:Dermatitis, Contact / Q000175:diagnosis / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000139:chemically induced* / Q000175:diagnosis; D005664:Furazolidone / Q000009:adverse effects*; D006229:Hand Dermatoses / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008297:Male; D010328:Patch Tests
D005664:Furazolidone