N5-acetyl-N5-hydroxy-L-ornithine-derived siderophore-carbacephalosporin beta-lactam conjugates: iron transport mediated drug delivery.
Dolence
E K
EK
Department of Chemistry, University of Notre Dame, Indiana 46556.
Minnick
A A
AA
Miller
M J
MJ
D001692:Biological Transport; D002511:Cephalosporins / Q000138:chemical synthesis / Q000494:pharmacology; D055598:Chemical Phenomena; D002621:Chemistry; D004926:Escherichia coli / Q000187:drug effects; D007501:Iron / Q000378:metabolism*; D007502:Iron Chelating Agents / Q000138:chemical synthesis / Q000494:pharmacology; D009952:Ornithine / Q000031:analogs & derivatives*; D017262:Siderophores; D013329:Structure-Activity Relationship
D002511:Cephalosporins; D007502:Iron Chelating Agents; D017262:Siderophores; C026739:carbacephems; D007501:Iron; D009952:Ornithine