[Combined analgetic drug treatment with ibuprofen after 3rd molar osteotomy].
In a placebo-controlled double-blind study using 3 x 400 mg ibuprofen during the surgical removal of impacted and dislocated third molars, a pain reduction of 64% (p = 0.05) as against the placebo control group could be demonstrated on the day of surgery and the first postoperative day. In view of the published results of a double-blind study on the reduction of cheek swelling using dexamethasone, the perioperative combination of 3 x 600 mg ibuprofen with 2 x 6 mg dexamethasone seems to be helpful in reliably preventing pain and swelling after dental surgery.
Schmelzeisen
R
R
Klinik und Poliklinik für Mund-, und Gesichtschirurgie, Medizinische Hochschule Hannover.
Buchweitz
I K
IK
Fricke
A
A
Frölich
J
J
D000293:Adolescent; D000328:Adult; D003907:Dexamethasone / Q000627:therapeutic use; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007052:Ibuprofen / Q000627:therapeutic use*; D008297:Male; D008964:Molar, Third / Q000601:surgery*; D010149:Postoperative Pain / Q000517:prevention & control*; D014095:Tooth, Impacted / Q000601:surgery*
D003907:Dexamethasone; D007052:Ibuprofen
Medikamentöse analgetische Kombinationsbehandlung nach Weisheitszahnosteotomien mit Ibuprofen.