title: Viral lower respiratory tract infections in Filipino children.
abstract: Viral causes of acute lower respiratory tract infection were studied prospectively between 15 June and 31 October 1984 in 312 Filipino children less than 5 years old living in periurban slums and middle-class housing. The cause was based on viral antigen detection, virus isolation, and antibody assays. There were 131 children (41.2%) who were admitted to the hospital, and 150 (47%) had an infiltrate on chest radiograph. A total of 198 viral infections were confirmed in 162 patients (51.9%), 42.3% with single viral infection and 9.6% with mixed (two or more) infection. The infections were measles (21.4%), influenza A (15.9%), parainfluenza types 1, 2, and 3 (8.8%), respiratory syncytial virus (7.1%), influenza B (5.8%), enteroviruses (5.1%), adenoviruses (3.9%), herpes simplex virus (1.6%), and cytomegalovirus (1.3%). Viral infections other than measles were seen in 39.7% of the cases. The presence of viral infection correlated with better nutritional status. Influenza A or B diagnosis was associated with mild forms of acute respiratory tract infection, measles and a preceding rash with severe disease.
authors: Second Department of Medicine, Helsinki University Central Hospital, Finland.
authors: P
authors: P
authors: Ruutu
authors: P
authors: P
authors: Halonen
authors: O
authors: O
authors: Meurman
authors: C
authors: C
authors: Torres
authors: F
authors: F
authors: Paladin
authors: K
authors: K
authors: Yamaoka
authors: T E
authors: TE
authors: Tupasi
mesh_terms: D000208:Acute Disease; D000258:Adenovirus Infections, Human / Q000175:diagnosis; D000914:Antibodies, Viral / Q000032:analysis; D000956:Antigens, Viral / Q000032:analysis; D001424:Bacterial Infections / Q000150:complications; D016009:Chi-Square Distribution; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D009980:Influenza A virus / Q000276:immunology / Q000302:isolation & purification; D009981:Influenza B virus / Q000276:immunology / Q000302:isolation & purification; D007251:Influenza, Human / Q000175:diagnosis; D008457:Measles / Q000175:diagnosis; D009752:Nutritional Status; D018184:Paramyxoviridae Infections / Q000175:diagnosis; D010679:Philippines; D011024:Pneumonia, Viral / Q000150:complications / Q000209:etiology*; D011446:Prospective Studies; D012136:Respiratory Syncytial Viruses / Q000302:isolation & purification; D010253:Respirovirus Infections / Q000175:diagnosis
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral