Clinical symptoms of Down syndrome are manifested in transgenic mice overexpressing the human Cu/Zn-superoxide dismutase gene.
Groner
Y
Y
Department of Molecular Genetics and Virology, Weizmann Institute of Science, Rehovot, Israel.
Avraham
K B
KB
Schickler
M
M
Yarom
R
R
Knobler
H
H
D000818:Animals; D001792:Blood Platelets / Q000378:metabolism; D004314:Down Syndrome / Q000097:blood / Q000235:genetics*; D015971:Gene Expression Regulation, Enzymologic / Q000502:physiology*; D006801:Humans; D051379:Mice; D008822:Mice, Transgenic; D009469:Neuromuscular Junction / Q000201:enzymology; D010641:Phenotype; D012701:Serotonin / Q000097:blood; D013482:Superoxide Dismutase / Q000235:genetics*; D014059:Tongue / Q000201:enzymology / Q000294:innervation
D012701:Serotonin; D013482:Superoxide Dismutase