Magnesium pidolate in the treatment of seasonal allergic rhinitis. Preliminary data.
This paper describes how the authors, after examining the calcium modulating action of the Mg ion and its antihistamine-like action, tested a salt containing Mg (Mg pidolate, MAG2) in the clinical treatment of seasonal allergic rhinitis. A total of 38 hayfever subjects were studied. They were given 1.5 g Mg salt three times a day for one month (oral MAG2 vials); placebo was used as a control in a randomized double-blind study. The efficacy of the product was assessed using the following criteria: intensity of rhinorrhoea, daily consumption of Kleenex tissues, number of sneezes in a day, intensity of lacrimation. The results were analysed using Student's t test and demonstrated the clinical efficacy of the product in the control of seasonal allergic rhinitis symptoms (P less than 0.001).
Cipolla
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Istituto di Clinica Medica III e Medicina del LAvoro, Bologna University, Italy.
Occhionero
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T
Orciari
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P
Lugo
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D'Antuono
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G
D000293:Adolescent; D000328:Adult; D002118:Calcium / Q000378:metabolism*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007765:Lacrimal Apparatus / Q000187:drug effects; D008274:Magnesium / Q000494:pharmacology*; D008297:Male; D009093:Mucus / Q000187:drug effects; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy*; D012912:Sneezing / Q000187:drug effects
D008274:Magnesium; D002118:Calcium