Mifepristone (RU 486) failure in an ovarian heterotopic pregnancy.
A patient treated with mifepristone (RU 486), which successfully induced abortion of an intrauterine pregnancy, was discovered to have a heterotopic ovarian pregnancy resistant to this antiprogesterone. The ovarian pregnancy was removed with operative laparoscopy. This case demonstrates for the first time that an ovarian pregnancy may be resistant to treatment with RU 486 at a dose adequate to abort an intrauterine pregnancy.
Levin
J H
JH
Division of Reproductive Endocrinology, University of Southern California School of Medicine, Los Angeles.
Lacarra
M
M
d'Ablaing
G
G
Grimes
D A
DA
Vermesh
M
M
D000028:Abortion, Induced; D000328:Adult; D002260:Carboprost; D005260:Female; D006801:Humans; D010535:Laparoscopy; D015735:Mifepristone; D010053:Ovary; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000628:therapy*
D015735:Mifepristone; D002260:Carboprost