[Isolation of Toxoplasma gondii from the saliva of patients with acquired immunodeficiency syndrome (AIDS)].
Toxoplasma gondii has been found in saliva of patients with toxoplasmosis. We tried to isolate parasites in saliva in patients with AIDS. As it is known, the finding of antitoxoplasma antibodies is not useful for diagnosis of cerebral abscess in toxoplasmosis occurring in AIDS patients in Brazil where 90% or more adults have serological evidence of past infection with Toxoplasma gondii. In 26 patients with AIDS, including six with tomographical evidence suggesting cerebral abscess caused by Toxoplasma gondii, no parasites were found in the saliva by the use of the mouse inoculation model. This trial that the search for Toxoplasma gondii in the saliva is not an alternative method for the diagnosis of toxoplasmosis in patients with AIDS.
Amato Neto
V
V
Laboratório de Investigação Médica-Parasitologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo.
Braz
L M
LM
Jamra
L M
LM
Higaki
Y
Y
Pasternak
J
J
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis; D006801:Humans; D009894:Opportunistic Infections / Q000175:diagnosis / Q000469:parasitology*; D012463:Saliva / Q000469:parasitology*; D014122:Toxoplasma / Q000276:immunology / Q000302:isolation & purification*; D016781:Toxoplasmosis, Cerebral / Q000175:diagnosis / Q000469:parasitology*
D000913:Antibodies, Protozoan
Pesquisa do Toxoplasma gondii na saliva de pacientes com síndrome da imunodeficiência adquirida (AIDS).