title: [Ganglioside GM3 derivatives and their immunomodulating effect].
abstract: The derivatives of ganglioside GM3-NeuLacCer. NeuLacSph and NeuAcLacSphAc-were obtained and their immunomodulating properties studied. These substances are shown to inhibit lymphocyte blast-transformation independently of their ceramide structure. On the contrary, the stimulation by the above GM3-derivatives of Con A-induced T-suppressor activity depends significantly on the structure of their ceramide moiety.
authors: E V
authors: EV
authors: Diatlovitskaia
authors: A B
authors: AB
authors: Koroleva
authors: V S
authors: VS
authors: Suskova
authors: V I
authors: VI
authors: Emets
authors: L V
authors: LV
authors: Sutiusheva
authors: L D
authors: LD
authors: Bergel'son
mesh_terms: D000276:Adjuvants, Immunologic / Q000302:isolation & purification; D002855:Chromatography, Thin Layer; D005679:G(M3) Ganglioside / Q000031:analogs & derivatives / Q000276:immunology* / Q000302:isolation & purification; D005732:Gangliosides / Q000276:immunology*; D006801:Humans; D008099:Liver / Q000032:analysis; D008213:Lymphocyte Activation; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
chemical_list: D000276:Adjuvants, Immunologic; D005679:G(M3) Ganglioside; D005732:Gangliosides
vernacular_title: Proizvodnye gangliozida GM3 i ikh immunomoduliruiushchiĭ éffekt.