Relapsing eruptive psoriasis and immunological changes triggered by growth hormone therapy in a growth hormone-deficient girl.
A 9.8-year-old girl with growth hormone (GH) deficiency and concomitant chronic and localized psoriasis of the groins and axillae showed repeated and sudden relapse of eruptive psoriasis after GH treatment. The aggravating effect of GH and the improvement of the skin condition after withdrawal suggests, at least in this case, that GH plays a significant role in the pathogenesis of psoriasis.
Maghnie
M
M
Department of Pediatrics, University of Pavia, IRCCS Policlinico S. Matteo, Italy.
Borroni
G
G
Larizza
D
D
Lorini
R
R
Girani
M A
MA
Rabbiosi
G
G
Severi
F
F
D002648:Child; D002908:Chronic Disease; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D006130:Growth Disorders / Q000188:drug therapy*; D013006:Growth Hormone / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D011565:Psoriasis / Q000139:chemically induced*; D012008:Recurrence
D013006:Growth Hormone