[Infectivity inhibition of HIV prototype strains by antibodies directed against a peptide sequence of mycoplasma].
Antibodies prepared against a peptide corresponding to the site of cyto-adherence of Mycoplasma genitalium adhesine inhibit or reduce the infectivity of the HIV-1BRU and HIV-2ROD strains of Human Immunodeficiency Virus in lymphoid cells. These results strengthen the hypothesis that some mycoplasmas may play an important part in HIV replication and pathogenicity.
Montagnier
L
L
Unité d'Oncologie virale et U.R.A. 1157, Laboratoire des Mycoplasmes, Institut Pasteur, Paris.
Berneman
D
D
Guétard
D
D
Blanchard
A
A
Chamaret
S
S
Rame
V
V
Van Rietschoten
J
J
Mabrouk
K
K
Bahraoui
E
E
D000595:Amino Acid Sequence; D000818:Animals; D000907:Antibodies, Bacterial / Q000276:immunology*; D003864:Depression, Chemical; D006678:HIV / Q000145:classification / Q000187:drug effects* / Q000276:immunology / Q000472:pathogenicity; D006801:Humans; D008969:Molecular Sequence Data; D009174:Mycoplasma / Q000737:chemistry / Q000276:immunology*; D011817:Rabbits
D000907:Antibodies, Bacterial
Inhibition de l'infectiosité de souches prototypes du VIH par des anticorps dirigés contre une séquence peptidique de mycoplasme.