[Meningococcal disease in the province of Córdoba (1983-1987].
This study reports the clinico-biologic characteristics, complications and the final events in 224 cases of meningococcal disease observed during a period of five years in the province of Cordoba. The prognostic factors of the disease were also evaluated. Patients were divided into three groups according to the diagnosis: meningitis, meningococcemia, and meningitis with meningococcemia. The incidence of each group was 18%, 22% and 60%, respectively. The 81.7% of the patients were below the age of 14 years. The most frequent symptoms were the fever (97.8%), vomitus (75%) and headache (52.2%) The more common exploratory findings were petechiae (76.8%) and nuchal rigidity (53.6%). Complications related to the illness were present in 27.3% of the cases. The clinical course showed a mortality rate of 6.3% with a complete recovery in 91% of patients. Sequelae was present in 2.7% of the cases. The absence of previous antibiotic therapy (p < 0.05), the presence of nuchal rigidity (p < 0.05), shock (p < 0.01), coma (p < 0.05), leukocytopenia (p < 0.001), and a prothrombin activity lower than 70% (p < 0.05) were associated with a bad prognosis.
Martínez de la Iglesia
J
J
Servicio de Urgencias, Hospital Regional Reina Sofía, Córdoba.
Montero Pérez
F J
FJ
Fernández-Crehuet Navajas
R
R
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000453:epidemiology / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D006801:Humans; D015994:Incidence; D007223:Infant; D008585:Meningitis, Meningococcal / Q000453:epidemiology; D008589:Meningococcal Infections / Q000097:blood / Q000134:cerebrospinal fluid / Q000453:epidemiology* / Q000382:microbiology; D008875:Middle Aged; D009345:Neisseria meningitidis / Q000302:isolation & purification; D011379:Prognosis; D011446:Prospective Studies; D013030:Spain / Q000453:epidemiology; D015996:Survival Rate; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents
Enfermedad meningocócica en la provincia de Córdoba (1983-1987).