title: Influence of sodium balance on atrial natriuretic factor in rats with one-kidney, one-clip renal hypertension.
abstract: The influence of sodium intake on the gene expression and circulating levels of atrial natriuretic factor (ANF) was investigated in unanesthetized rats with one-kidney, one-clip renal hypertension. After clipping, the rats were maintained for 3 weeks either on a salt-deficient (n = 11) or a regular-sodium diet (n = 10). Animals which had received the regular-sodium diet exhibited significantly higher ANF mRNA levels in their right and left atria than salt-restricted animals, whereas there was no significant difference in plasma ANF levels.
authors: Division of Hypertension, University Hospital, Lausanne, Switzerland.
authors: A L
authors: AL
authors: Lattion
authors: J P
authors: JP
authors: Flückiger
authors: B
authors: B
authors: Waeber
authors: J
authors: J
authors: Nussberger
authors: J F
authors: JF
authors: Aubert
authors: H R
authors: HR
authors: Brunner
mesh_terms: D000818:Animals; D009320:Atrial Natriuretic Factor / Q000097:blood* / Q000235:genetics; D004039:Diet, Sodium-Restricted; D015870:Gene Expression; D006325:Heart Atria / Q000378:metabolism; D006978:Hypertension, Renovascular / Q000378:metabolism*; D008297:Male; D012333:RNA, Messenger / Q000378:metabolism; D051381:Rats; D011919:Rats, Inbred Strains; D012964:Sodium / Q000008:administration & dosage* / Q000494:pharmacology; D014882:Water-Electrolyte Balance
chemical_list: D012333:RNA, Messenger; D009320:Atrial Natriuretic Factor; D012964:Sodium