[Cardiotoxicity of emetine].
Emetine is still an important agent for the treatment of invasive intestinal amebiasis and amebic liver abscess. Its most relevant side effect is its well documented cardiotoxicity. The authors review the hypotheses that have been suggested concerning the mechanism of this cardiotoxic action.
Marino
A
A
Istituto di Farmacologia Sperimentale e Clinica, II Facoltà di Medicina e Chiruragia dell'Università di Napoli.
Costa
R
R
De Natale
G
G
D000818:Animals; D004640:Emetine / Q000009:adverse effects* / Q000494:pharmacology; D006321:Heart / Q000187:drug effects* / Q000503:physiopathology; D006801:Humans; D009124:Muscle Proteins / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism / Q000473:pathology; D011500:Protein Synthesis Inhibitors / Q000494:pharmacology
D009124:Muscle Proteins; D011500:Protein Synthesis Inhibitors; D004640:Emetine
La cardiotossicità dell'emetina.