title: Effect of malathion and methyl-parathion on rat liver enzymes.
abstract: The effect of sub-lethal doses of Malathion and Methyl-parathion was studied on the rat liver enzymes. Intravenous administration of both insecticides at weekly interval for four weeks resulted in increase in heart and spleen weight. Short term (24 hr.) and long term (4 weeks) treatment with insecticides resulted in increased specific activities of liver enzymes, Acid phosphatase, Alkaline phosphatase, Glutamate dehydrogenase, Glutamate oxaloacetate transaminase and Glutamate pyruvate transaminase. The increase in enzyme activity was not as profound when the insecticide administration was spread over 4 weeks. Malathion had greater effect than Methyl-parathion on the biochemical parameters studied.
authors: Entomological Research Labs., National Agricultural Research Centre, Islamabad.
authors: A
authors: A
authors: Jabbar
authors: S A
authors: SA
authors: Khawaja
authors: A
authors: A
authors: Iqbal
authors: S A
authors: SA
authors: Malik
mesh_terms: D000818:Animals; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008294:Malathion / Q000633:toxicity*; D008297:Male; D008743:Methyl Parathion / Q000633:toxicity*; D051381:Rats
chemical_list: D008743:Methyl Parathion; D008294:Malathion