Plastics from bacteria and for bacteria: poly(beta-hydroxyalkanoates) as natural, biocompatible, and biodegradable polyesters.
Hence, PHB belongs to the family of poly(beta-hydroxyalkanoates), PHA, all of which are usually formed as intracellular inclusions under unbalanced growth conditions. Recently, it became of industrial interest to evaluate PHA polyesters as natural, biodegradable, and biocompatible plastics for a wide range of possible applications such as surgical sutures or packaging containers. For industrial applications, the controlled incorporation of repeating units with different chain lengths into a series of copolymers is desirable in order to produce polyesters with a range of material properties because physical and chemical characteristics depend strongly on the polymer composition. Such "tailormade" copolymers can be produced under controlled growth conditions, in that if a defined mixture of substrates for a certain type of microorganisms is supplied, a well defined and reproducible copolymer is formed.
Brandl
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Department of Biochemistry, University of Massachusetts, Amherst 01003.
Gross
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Lenz
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Fuller
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D001419:Bacteria / Q000378:metabolism*; D001672:Biocompatible Materials; D001673:Biodegradation, Environmental; D002616:Chemical Engineering; D010969:Plastics; D011091:Polyesters
D001672:Biocompatible Materials; D010969:Plastics; D011091:Polyesters