Drug resistance trends in Mycobacterium tuberculosis: Blackburn 1985-89.
Drug resistance in Mycobacterium tuberculosis fell from 15.2% in 1980-1984 to 6.5% in 1985-89 in the Indian subcontinent (ISC) ethnic group and remained low in the white ethnic group. Resistance to isoniazid, which is of particular clinical significance, fell from 6.1% in 1980-84 to 2.7% in 1985-1989 in the ISC group. Factors which may affect this trend to reduction are discussed.
Ormerod
L P
LP
Chest Clinic, Blackburn Royal Infirmary, Lancs, UK.
Harrison
J M
JM
Wright
P A
PA
D000995:Antitubercular Agents / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D004739:England; D006801:Humans; D007194:India / Q000208:ethnology; D007538:Isoniazid / Q000494:pharmacology; D008137:Longitudinal Studies; D009169:Mycobacterium tuberculosis / Q000187:drug effects*; D014376:Tuberculosis / Q000208:ethnology / Q000382:microbiology*
D000995:Antitubercular Agents; D007538:Isoniazid