title: Treatment of severe acne with isotretinoin in patients with inflammatory bowel disease.
abstract: Four patients with inflammatory bowel disease and severe cystic acne were treated with isotretinoin. Two patients had a successful course of treatment without any gastrointestinal side-effects. One patient had two episodes of profuse rectal bleeding that were probably related to pre-existing haemorrhoids. The fourth patient had a flare-up of his Crohn's disease after starting isotretinoin.
authors: Department of Dermatology, Royal Berkshire Hospital, Reading, U.K.
authors: K M
authors: KM
authors: Godfrey
authors: M P
authors: MP
authors: James
mesh_terms: D000152:Acne Vulgaris / Q000150:complications / Q000188:drug therapy*; D000293:Adolescent; D000328:Adult; D003424:Crohn Disease / Q000139:chemically induced; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006484:Hemorrhoids / Q000150:complications; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000150:complications*; D015474:Isotretinoin / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D012002:Rectal Diseases / Q000209:etiology
chemical_list: D015474:Isotretinoin