Lichen planus induced by flunarizine.
A 56-year-old man developed lichen planus while taking flunarizine, a di-fluorinated derivate of cinnarizine. Induction of lichen planus by cinnarizine therapy has been described but the precise etiopathological mechanism is unclear. Although flunarizine is widely prescribed, lichen planus induced (?) by this drug has, to our knowledge, never been reported.
Suys
E
E
Department of Dermatology, Free University, Brussels, Belgium.
De Coninck
A
A
De Pauw
I
I
Roseeuw
D
D
D001161:Arteriosclerosis / Q000188:drug therapy; D003875:Drug Eruptions / Q000209:etiology* / Q000276:immunology; D005444:Flunarizine / Q000008:administration & dosage / Q000009:adverse effects*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008010:Lichen Planus / Q000139:chemically induced* / Q000276:immunology; D008297:Male; D008875:Middle Aged
D007136:Immunoglobulins; D005444:Flunarizine