Supervision of cellular response to radiation by human interferon.
Human interferon (HuIFN) conferred human RSa cells to increased resistance to ultraviolet light, 4-nitroquinoline-1-oxide and X-ray in association with enhancement of DNA-repair capacity. The HuIFN actions were summarized by the supervision of cellular response, possibly via plasminogen activator-like protease induction.
Suzuki
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Department of Biochemistry, School of Medicine, Chiba University, Japan.
Suzuki
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H
D015112:4-Nitroquinoline-1-oxide / Q000494:pharmacology; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects / Q000528:radiation effects; D004260:DNA Repair / Q000187:drug effects / Q000528:radiation effects; D006801:Humans; D007370:Interferon Type I / Q000494:pharmacology*; D010960:Plasminogen Activators / Q000096:biosynthesis; D011836:Radiation Tolerance / Q000187:drug effects*; D014466:Ultraviolet Rays
D007370:Interferon Type I; D015112:4-Nitroquinoline-1-oxide; D010960:Plasminogen Activators