D-amino acids in mouse tissues are not of microbial origin.
Neutral free D-amino acid contents in the serum, kidney, liver, brain, small intestine and urine in germ-free mice and those in specific pathogen-free mice were compared. No significant difference was found. This strongly suggests that the free D-amino acids which were shown to be present in mice in our previous work did not originate from the enteric microbial flora.
Nagata
Y
Y
Department of Biochemistry, Sapporo Medical College, Japan.
Akino
T
T
D000596:Amino Acids / Q000097:blood / Q000378:metabolism* / Q000652:urine; D000818:Animals; D001419:Bacteria / Q000378:metabolism*; D001921:Brain / Q000378:metabolism; D005856:Germ-Free Life; D007413:Intestinal Mucosa / Q000378:metabolism; D007422:Intestines / Q000382:microbiology; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D013047:Specific Pathogen-Free Organisms
D000596:Amino Acids