A combination of Laserthermia and chemotherapy for the treatment human gastric cancers transplanted into nude mice.
The effects of Laserthermia plus chemotherapy on a human gastric cancer transplanted into nude mice was investigated. Three different treatment regimes were tested. The relative tumor growth rate according to the Battele Columbus Laboratories protocol, was as follows. 5-FU chemotherapy, 54%; Laserthermia, 31%; and combined treatment with 5-FU and Laserthermia, 21%. The greatest degree of tumor regression was achieved in the combined therapy group. It is suggested that the combination therapy of Laserthermia plus antitumor agents may be useful in the treatment of gastric cancer in humans.
Narumi
H
H
Sixth Department of Internal Medicine, School of Medicine, Tokai University, Japan.
Suzuki
S
S
Miwa
T
T
D000230:Adenocarcinoma / Q000188:drug therapy / Q000473:pathology / Q000628:therapy*; D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D006801:Humans; D006979:Hyperthermia, Induced; D053685:Laser Therapy; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation; D013274:Stomach Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000628:therapy*
D000970:Antineoplastic Agents