title: The projection of GABA-ergic neurons of the medial terminal accessory optic nucleus to the pretectum in the rat.
abstract: Large numbers of neurons were retrogradely labeled in both the dorsal and ventral medial terminal nucleus (MTN) after fluoro-gold injections into the rat pretectal nucleus of the optic tract/dorsal terminal nucleus (NOT/DTN). Fluorescence immunocytochemistry for GABA in the same brains revealed GABA-positive neurons distributed mainly in the dorsal MTN. Approximately half of all the GABAergic neurons in the MTN were double-labeled. Therefore, GABAergic neurons comprise a significant component of the MTN-NOT/DTN projection which most likely inhibits the pretectal pathway mediating horizontal optokinetic nystagmus.
authors: Department of Anatomy and Neurobiology, California College of Medicine, University of California, Irvine 92717.
authors: R A
authors: RA
authors: Giolli
authors: R J
authors: RJ
authors: Clarke
authors: Y
authors: Y
authors: Torigoe
authors: R H
authors: RH
authors: Blanks
authors: J H
authors: JH
authors: Fallon
mesh_terms: D000818:Animals; D005456:Fluorescent Dyes; D007150:Immunohistochemistry; D008856:Microscopy, Fluorescence; D009476:Neurons, Efferent / Q000502:physiology*; D051381:Rats; D013266:Stilbamidines; D013477:Superior Colliculi / Q000033:anatomy & histology* / Q000502:physiology; D014795:Visual Pathways / Q000033:anatomy & histology* / Q000502:physiology; D005680:gamma-Aminobutyric Acid / Q000502:physiology*
chemical_list: C049774:2-hydroxy-4,4'-diamidinostilbene, methanesulfonate salt; D005456:Fluorescent Dyes; D013266:Stilbamidines; D005680:gamma-Aminobutyric Acid