Multiple-sited (heterotopic) pregnancy after in vitro fertilization and gamete intrafallopian transfer.
Pregnancies occurring simultaneously in different body sites (heterotopic pregnancies) are a rare condition thought to occur in 1 of 30,000 spontaneous pregnancies. Individual cases may occur after in vitro fertilization (IVF) or gamete intrafallopian transfer (GIFT). In the past 4 1/2 years, our unit has performed 6,204 IVF/GIFT or pronuclear stage transfer cycles of treatment. Ten such pregnancies proven by surgical, ultrasound, and histological diagnosis have occurred. In the same period 640 IVF, 355 GIFT, and 6 pronuclear stage transfer clinical pregnancies were achieved. This suggests that the incidence of heterotopic pregnancy after assisted reproduction is closer to 1 of 100 pregnancies. Clinicians managing early complications of IVF, GIFT, and/or pronuclear stage transfer pregnancies should be aware of this relatively high incidence of concomitant intrauterine and extrauterine pregnancy.
Molloy
D
D
Queensland Fertility Group, Watkins Medical Centre, Brisbane, Australia.
Deambrosis
W
W
Keeping
D
D
Hynes
J
J
Harrison
K
K
Hennessey
J
J
D005260:Female; D005307:Fertilization in Vitro; D015181:Gamete Intrafallopian Transfer / Q000009:adverse effects*; D006801:Humans; D010535:Laparoscopy; D008875:Middle Aged; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000453:epidemiology*; D011271:Pregnancy, Ectopic / Q000209:etiology / Q000601:surgery; D011272:Pregnancy, Multiple; D014463:Ultrasonography