Benzodiazepine binding sites in amygdala and hippocampus of depressed suicide victims.
Benzodiazepine binding was measured in amygdala and hippocampus from 19 suicides in whom a firm diagnosis of depression was established retrospectively, and 19 well-matched controls. The number and affinity of benzodiazepine binding sites did not differ significantly between the drug-free or drug-treated suicides and controls.
Stocks
G M
GM
Department of Pharmacology and Clinical Pharmacology, St George's Hospital Medical School, London, U.K.
Cheetham
S C
SC
Crompton
M R
MR
Katona
C L
CL
Horton
R W
RW
D000293:Adolescent; D000328:Adult; D000679:Amygdala / Q000378:metabolism*; D000928:Antidepressive Agents / Q000493:pharmacokinetics; D003866:Depressive Disorder / Q000188:drug therapy / Q000378:metabolism*; D005260:Female; D006624:Hippocampus / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011619:Psychotropic Drugs / Q000493:pharmacokinetics; D011963:Receptors, GABA-A / Q000378:metabolism*; D013405:Suicide
D000928:Antidepressive Agents; D011619:Psychotropic Drugs; D011963:Receptors, GABA-A