title: An immunohistological study of spontaneous regression of condylomata acuminata.
abstract: An immunohistological study of four men whose perianal warts were undergoing spontaneous regression was undertaken, and the results compared with those obtained from non-regressing condylomata from six men. CD4+ and CD8+ cells were noted in the stroma of each wart, but there was no clear difference in the density of the infiltrate between regressing and non-regressing warts. Natural killer cells (CD16+ and CD57+) were only noted in the stroma and epidermis of regressing warts. Possible immunological mechanisms of regression of condylomata acuminata are discussed.
authors: Department of Medicine, Edinburgh Royal Infirmary, UK.
authors: P E
authors: PE
authors: Bishop
authors: A
authors: A
authors: McMillan
authors: S
authors: S
authors: Fletcher
mesh_terms: D001005:Anus Neoplasms / Q000276:immunology*; D003218:Condylomata Acuminata / Q000276:immunology*; D005834:Genital Neoplasms, Male / Q000276:immunology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009365:Neoplasm Regression, Spontaneous / Q000276:immunology*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology; D050378:T-Lymphocytes, Regulatory / Q000276:immunology