title: Hairy cell leukemia involving an inguinal hernial sac.
abstract: A 37-year-old man with hairy cell leukemia was found incidentally to have a right inguinal hernia. Microscopic examination of the resected herniorrhaphy specimen disclosed dense transmural infiltration by hairy cells. Electron-microscopic and immunoperoxidase studies confirmed the presence of surface cytoplasmic projections and B cell phenotype, respectively, of the infiltrating cells. This case is, to our knowledge, the first reported instance of hairy cell leukemia involving a hernial sac and demonstrates the capacity of hairy cells to infiltrate unexpected soft-tissue sites.
authors: Department of Pathology, Ohio State University College of Medicine, Columbus.
authors: M J
authors: MJ
authors: Melaragno
authors: K S
authors: KS
authors: Theil
authors: W L
authors: WL
authors: Marsh
authors: D D
authors: DD
authors: Sedmak
authors: B A
authors: BA
authors: Bouroncle
mesh_terms: D000328:Adult; D006552:Hernia, Inguinal / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007943:Leukemia, Hairy Cell / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D008297:Male; D009361:Neoplasm Invasiveness; D013154:Spleen / Q000473:pathology; D013156:Splenectomy