Comparative expression of the mRNA for three intestinal hydrolases during postnatal development in the rat.
The distribution of the mRNA for intestinal aminopeptidase-N, lactase-phlorizin hydrolase and sucrase-isomaltase was compared during rat postnatal development as well as along the longitudinal axis of the intestinal tract including small-intestine and colon. We found out that each mRNA exhibited a specific pattern of accumulation, suggesting proper regulation steps for the expression of the corresponding digestive enzymes.
Freund
J N
JN
INSERM Unité 61, Strasbourg, France.
Torp
N
N
Duluc
I
I
Foltzer-Jourdainne
C
C
Danielsen
M
M
Raul
F
F
D000626:Aminopeptidases / Q000235:genetics*; D000818:Animals; D003106:Colon / Q000737:chemistry; D015342:DNA Probes; D015971:Gene Expression Regulation, Enzymologic; D007082:Ileum / Q000737:chemistry; D007583:Jejunum / Q000737:chemistry; D012333:RNA, Messenger / Q000032:analysis*; D051381:Rats; D011919:Rats, Inbred Strains / Q000254:growth & development; D001616:beta-Galactosidase / Q000235:genetics*
D015342:DNA Probes; D012333:RNA, Messenger; D001616:beta-Galactosidase; D000626:Aminopeptidases