title: The amino acid sequence of avian thymic hormone, a parvalbumin.
abstract: The complete amino acid sequence of 'avian thymic hormone' (ATH), a protein from thymus tissue that appears to promote immune maturation in chicken bone marrow cells in culture, is presented. The sequence was obtained from sequences of ATH peptides isolated by HPLC after tryptic, chymotryptic, peptic or S aureus V8 protease digestions. The protein is a parvalbumin consisting of 108 residues with a blocked amino terminus, a single cysteine, tyrosine, proline and arginine and no histidine, methionine or tryptophan. This is the first amino acid sequence of a parvalbumin which is not derived from muscle tissue.
authors: Department of Biochemistry, University of Georgia, Athens 30602.
authors: J M
authors: JM
authors: Brewer
authors: J K
authors: JK
authors: Wunderlich
authors: W L
authors: WL
authors: Ragland
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002645:Chickens; D002851:Chromatography, High Pressure Liquid; D008969:Molecular Sequence Data; D009132:Muscles / Q000737:chemistry; D010320:Parvalbumins / Q000737:chemistry*; D013950:Thymus Gland / Q000737:chemistry*; D013951:Thymus Hormones / Q000737:chemistry*
chemical_list: D010320:Parvalbumins; D013951:Thymus Hormones