Endogenous synthesis of N-methyl-1,2,3,4-tetrahydroisoquinoline, a precursor of N-methylisoquinolinium ion, in the brains of primates with parkinsonism after systemic administration of 1,2,3,4-tetrahydroisoquinoline.
Niwa
T
T
Department of Internal Medicine, Nagoya University Branch Hospital, Japan.
Yoshizumi
H
H
Tatematsu
A
A
Matsuura
S
S
Yoshida
M
M
Kawachi
M
M
Naoi
M
M
Nagatsu
T
T
D000818:Animals; D001921:Brain / Q000378:metabolism* / Q000473:pathology; D001923:Brain Chemistry; D002143:Callitrichinae / Q000378:metabolism*; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D007279:Injections, Subcutaneous; D007546:Isoquinolines / Q000008:administration & dosage / Q000032:analysis / Q000378:metabolism*; D008297:Male; D010300:Parkinson Disease / Q000378:metabolism* / Q000473:pathology; D011806:Quinolinium Compounds / Q000032:analysis / Q000378:metabolism*; D044005:Tetrahydroisoquinolines
D007546:Isoquinolines; D011806:Quinolinium Compounds; D044005:Tetrahydroisoquinolines; C051351:N-methylisoquinolinium; C050386:1-methyl-1,2,3,4-tetrahydroisoquinoline