title: New diagnostic method for cystic fibrosis.
abstract: We report 3 cases where the diagnosis of cystic fibrosis (CF) was either confirmed or refuted by studies of chloride secretion in intestinal mucosal biopsies. In one case a heterozygous state was indicated and later confirmed by gene probe studies. The technique clearly distinguishes between CF and control patients and can provide a rapid diagnosis even in the neonatal period.
authors: Department of Paediatrics, University of Sheffield.
authors: C J
authors: CJ
authors: Taylor
authors: P S
authors: PS
authors: Baxter
authors: J
authors: J
authors: Dickson
authors: J
authors: J
authors: Hardcastle
authors: P T
authors: PT
authors: Hardcastle
authors: J
authors: J
authors: Goldhill
mesh_terms: D002675:Child, Preschool; D002712:Chlorides / Q000378:metabolism; D003550:Cystic Fibrosis / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism; D006801:Humans; D007231:Infant, Newborn; D007413:Intestinal Mucosa / Q000378:metabolism
chemical_list: D002712:Chlorides