[Haemophilus influenzae carriers among child care personnel: its prevalence and the efficacy of enoxacin in its elimination].
In a previous study we observed that 6% of adult and 18% of children contacts of H. influenzae infected patients became carriers of the bacillus. We studied 1296 adults involved in children care, 398 from day care centers and 898 from hospitals in Santiago. A pharyngeal sample was cultured in chocolate agar plus bacitracin (300 mg/ml) and incubated at 37 degrees C in a 5-10% CO2 atmosphere for 18-24 h. Isolates of H influenzae were biotypified and serogrouped according to international recommendations. We observed that 2.4% of subjects were H influenzae carriers. Thirty carriers were treated with 2 doses of enoxacin, 440 mg. All became free of H influenzae at a 30-day follow-up.
Prado
V
V
Unidad de Microbiología, Facultad de Medicina, Universidad de Chile.
Trucco
O
O
Molina
E
E
Flaskamp
R
R
Portilla
M
M
D000328:Adult; D002353:Carrier State / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D002648:Child; D002656:Child Day Care Centers / Q000706:statistics & numerical data; D002675:Child, Preschool; D002677:Chile / Q000453:epidemiology; D004341:Drug Evaluation; D004361:Drug Tolerance; D015365:Enoxacin / Q000627:therapeutic use*; D005260:Female; D006192:Haemophilus Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D006193:Haemophilus influenzae / Q000302:isolation & purification; D006776:Hospitals, Pediatric / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D010608:Pharyngeal Diseases / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D015995:Prevalence; D000078329:Workforce
D015365:Enoxacin
Portadores de Haemophilus influenzae en personal de atención infantil: prevalencia y eficacia de enoxacina en la erradicación.