title: Diagnostic significance of motor evoked potentials in space-occupying lesions of the brain stem and spinal cord.
abstract: Motor evoked potentials (MEP) were examined in 50 patients with space-occupying lesions of the brain stem and spinal cord. MEP findings were correlated with the motor status as established by clinical examination. The results clearly show the high sensitivity of MEP for detection of motor deficits: 17 recordings (77%) from the thenar muscle and 42 (84%) from the anterior tibial muscle correlated correctly with the clinical motor status. False-positive results were found in 5 (23%) thenar recordings and 8 (16%) and anterior tibial recordings. False-negative correlation was not observed. The high rate of false-positive results appears to indicate that MEP detect subclinical motor deficits. This electrophysiological test is therefore recommended, especially when involvement of the descending pathways is suspected and clinical examination reveals no abnormality.
authors: Department of Neurosurgery, Medical School, University of Tübingen, Federal Republic of Germany.
authors: J
authors: J
authors: Zentner
authors: G
authors: G
authors: Rieder
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000503:physiopathology; D001933:Brain Stem / Q000503:physiopathology*; D004292:Dominance, Cerebral / Q000502:physiology; D004558:Electric Stimulation; D004569:Electroencephalography; D004576:Electromyography; D005071:Evoked Potentials / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009044:Motor Cortex / Q000503:physiopathology*; D009132:Muscles / Q000294:innervation; D013116:Spinal Cord / Q000503:physiopathology; D013120:Spinal Cord Neoplasms / Q000175:diagnosis* / Q000503:physiopathology