Self-poisoning with the beta-blocker bisoprolol.
A case of bisoprolol self-poisoning resulting in full recovery of the patient is described. The peak plasma level of bisoprolol was 541 ng ml-1. Sinus bradycardia was the only symptom observed, suggesting that cardioselectivity and absence of membrane stabilizing activity contribute to reduce the severity of beta-blocker intoxication.
Tracqui
A
A
Institut de Médecine Légale, Faculté de Médecine de Strasbourg.
Kintz
P
P
Mangin
P
P
Lenoir
B
B
D000328:Adult; D001285:Atropine / Q000627:therapeutic use; D017298:Bisoprolol; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D008297:Male; D011412:Propanolamines / Q000493:pharmacokinetics / Q000506:poisoning*; D013405:Suicide
D011412:Propanolamines; D001285:Atropine; D017298:Bisoprolol