title: Characteristics of paroxysmal nocturnal hemoglobinuria in China. Clinical analysis of 476 cases.
abstract: 476 cases of paroxysmal nocturnal hemoglobinuria (PNH) were analysed and compared with PNH patients in foreign countries and its classification was discussed. The clinical characteristics in Chinese PNH patients were: males were affected more; the age of onset was young; more common in north China; hemoglobinuria as an initial symptom was less common; thrombosis as a complication was relatively rare; the common causes of death were heart failure, infections and hemorrhage; and bone marrow picture might show mild dyshematopoiesis.
authors: Institute of Hematology, Chinese Academy of Medical Sciences, Tianjin.
authors: X F
authors: XF
authors: Le
authors: T Y
authors: TY
authors: Yang
authors: X Y
authors: XY
authors: Yang
authors: X M
authors: XM
authors: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001856:Bone Marrow Examination; D002648:Child; D002681:China / Q000453:epidemiology; D005260:Female; D006457:Hemoglobinuria, Paroxysmal / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis