[A progressive gastric cancer in which preoperative oral chemotherapy resulted in a histopathological "Grade 2" rating].
This paper describes a case of a Borrmann type 3 gastric cancer, in which the preoperative intermittent oral administration of 5'-DFUR over a short term resulted in a histopathological rating of Grade 2. A 56-year-old man preoperatively received an intermittent, oral administration of 5'-DFUR, 2, 100 mg/day. An upper gastrointestinal series and endoscopy revealed macroscopically an extremely slight remission. Histopathologically, however, a widespread, remarkable degeneration of cancer cells and fibrinogenesis of the framework were observed, these results leading to a change of rating to Grade 2.
Hiromoto
M
M
Division of Surgery, Toyosu Hospital, Showa Univ. School of Med.
Yasui
A
A
Nishida
Y
Y
Kumagai
K
K
Sanada
Y
Y
Masuo
K
K
Kobayashi
K
K
Nakayama
A
A
D000230:Adenocarcinoma / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D005467:Floxuridine / Q000008:administration & dosage / Q000627:therapeutic use*; D005743:Gastrectomy; D005773:Gastroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D012074:Remission Induction; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery
D000970:Antineoplastic Agents; D005467:Floxuridine; C025034:doxifluridine