Factor H polymorphism, typing by isoelectrofocusing and immunoblotting: no association with rheumatoid arthritis.
The genetic polymorphism of human factor H (beta 1H) was investigated by a combination of isoelectrofocusing and immunoblotting. This simple method is reliable and economical. The allelic frequencies in the Newfoundland population were estimated to be 0.597 and 0.403 for FH*1 and FH*2, respectively (129 individuals typed). No association of factor H types with rheumatoid arthritis was found (111 patients typed).
Zhou
M
M
Memorial University of Newfoundland, School of Medicine, St. John's, Canada.
Larsen
B
B
D001172:Arthritis, Rheumatoid / Q000235:genetics*; D003180:Complement C3b Inactivator Proteins / Q000235:genetics*; D017242:Complement Factor H; D005787:Gene Frequency; D006801:Humans; D015151:Immunoblotting; D007525:Isoelectric Focusing; D009523:Newfoundland and Labrador; D011110:Polymorphism, Genetic
C493495:CFH protein, human; D003180:Complement C3b Inactivator Proteins; D017242:Complement Factor H