Four-year follow-up of twenty-four first-episode manic patients.
Twenty-four first-episode manic patients were followed to investigate the 4-year outcome after recovery from a manic episode. Patients had no documented previous manic or depressive episodes. The presence of psychotic features during the index episode and a history of alcoholism were statistically significant predictors of a shorter time in remission. Low occupational status at baseline predicted poor global social adjustment at 4 years. Also, a larger correlation among outcome measures was found at 48 than at 6 months. The importance of controlling for presence of multiple episodes in outcome studies is emphasized.
Tohen
M
M
Department of Psychiatry, Harvard School of Medicine, Boston, MA.
Waternaux
C M
CM
Tsuang
M T
MT
Hunt
A T
AT
D001714:Bipolar Disorder / Q000175:diagnosis* / Q000523:psychology; D015331:Cohort Studies; D005500:Follow-Up Studies; D006801:Humans; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D012008:Recurrence; D012917:Social Adjustment