[Fenoterol-ipratropium nebulization in infants with obstructive bronchial syndrome].
A double blind prospective study was done in 120 infants with acute obstructive bronchial disease. One half of them received combined fenoterol-ipratropium solution by inhalation in three different dose schedules while the other half was given inhalation normal saline solution for comparative purposes. Statistical analysis showed a significant difference in favor of fenoterol-ipratropium treatment over controls as to severity of bronchial obstruction, days of recovery and the need of additional bronchodilator drugs. However, no significant differences in the response of these parameters were noted among patients receiving different dose schedules of fenoterol-ipratropium. The combination of fenoterol-ipratropium showed a beneficial bronchodilator effect in patients with acute obstructive bronchial disease.
Calvo
M
M
Instituto de Pediatría, Facultad de Medicina, Universidad Austral de Chile.
Grob
K
K
Herrmann
M
M
Marín
F
F
D000208:Acute Disease; D000280:Administration, Inhalation; D001982:Bronchial Diseases / Q000188:drug therapy*; D001993:Bronchodilator Agents / Q000627:therapeutic use*; D004311:Double-Blind Method; D004338:Drug Combinations; D005260:Female; D005280:Fenoterol / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D009241:Ipratropium / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D011446:Prospective Studies; D012965:Sodium Chloride / Q000627:therapeutic use
D001993:Bronchodilator Agents; D004338:Drug Combinations; C030809:fenoterol, ipratropium drug combination; D005280:Fenoterol; D012965:Sodium Chloride; D009241:Ipratropium
Nebulizaciones de fenoterol-ipratropio en lactantes con síndrome bronquial obstructivo.