Do the cardiac glands exist? 6. The cat.
We performed histological and histochemical investigations on so-called cardiac glands and gastric glands in the cat to clarify the existence of the former. 1. Cardiac glands possess some parietal cells and strongly PAS-positive glandular cells in the base of glands containing a small number of fine pepsinogen granules. Consequently, we consider them to be undifferentiated gastric glands. Therefore, the cardiac glands do not exist in the cat. 2. Glandular cells in the basal part of undifferentiated gastric glands react negatively or very weakly to AB (pH 2.5 and 0.5) and present a red color with PAS-AB (pH 2.5) stain. 3. A large number of strongly PAS-positive and pepsinogen granule containing cells are distributed not only in the glandular body but also in the basal part of the glands. These cells are immature chief cells. 4. The above-mentioned cells react weakly or moderately to AB (pH 2.5 and 0.5) and stain light purple by PAS-AB (pH 2.5). They possess weak and strong acid mucopolysaccharides and sialomucin. 5. Mature chief cells are distributed mainly in the glandular base. They are PAS-negative, react moderately or strongly to AB (pH 2.5 and 0.5), and present a dark color of AB with PAS-AB (pH 2.5) stain. Consequently, it can be concluded that these cells contain weak and strong acid mucopolysaccharides but no sialomucin. 6. Mature chief cells possess no sialomucin. However, they present stronger reactions to AB (pH 2.5 and 0.5) than those in immature chief cells. This characteristic does not appear in man and many other types of mammals studied.
Imai
M
M
Department of Anatomy, Kanazawa Medical University, Ishikawa, Japan.
Shibata
T
T
Moriguchi
K
K
Yamamoto
M
M
Kinbara
M
M
D000818:Animals; D002415:Cats; D005753:Gastric Mucosa / Q000166:cytology / Q000378:metabolism; D006025:Glycosaminoglycans / Q000378:metabolism; D006651:Histocytochemistry / Q000379:methods; D009077:Mucins / Q000378:metabolism; D010295:Parietal Cells, Gastric / Q000166:cytology* / Q000378:metabolism; D010435:Pepsinogens / Q000378:metabolism; D010503:Periodic Acid-Schiff Reaction; D052116:Sialomucins; D013270:Stomach / Q000033:anatomy & histology* / Q000166:cytology
D006025:Glycosaminoglycans; D009077:Mucins; D010435:Pepsinogens; D052116:Sialomucins