[Result and indication of photodynamic therapy in the treatment of malignant tumors--analysis of 165 patients].
Evaluation of the effect of photodynamic therapy (PDT) on cancers is presented. Indication of PDT in the treatment of 165 cancer patients, including 68 superficial, 33 head and neck, 57 bladder and 7 other cancers treated from Sept. 1981 through 1985 is reported. The overall effective rate was 83.6%. The immediate response rates were as follows: complete response 58.2%, marked response 13.3%, mild response 12.1% and no response 16.4%. The longest cancer-free survival was over six years. Based on this material the indications of PDT on cancer are suggested as: 1. superficial and early cancers; 2. orifice obstruction in the alimentary or respiratory tract; 3. local residual or recurrent cancer after surgery or radiotherapy; 4. bladder cancer. The disadvantages of PDT are discussed.
Cai
W M
WM
Cancer Hospital, Chinese Academy of Medical Sciences, Beijing.
D002294:Carcinoma, Squamous Cell / Q000188:drug therapy; D002295:Carcinoma, Transitional Cell / Q000188:drug therapy; D017324:Hematoporphyrin Derivative; D006414:Hematoporphyrin Photoradiation; D006415:Hematoporphyrins / Q000627:therapeutic use*; D006801:Humans; D010778:Photochemotherapy; D011838:Radiation-Sensitizing Agents / Q000627:therapeutic use*; D012878:Skin Neoplasms / Q000188:drug therapy*; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy
D006415:Hematoporphyrins; D011838:Radiation-Sensitizing Agents; D017324:Hematoporphyrin Derivative