title: In vitro susceptibilities of oral pigmented Bacteroides species to trospectomycin and other selected antimicrobial agents.
abstract: The in vitro activity of trospectomycin against 97 clinical isolates of oral pigmented Bacteroides species was compared with the activities of five other antimicrobial agents. At 4 micrograms/ml, more than 90% of isolates were inhibited by trospectomycin. Overall, strains that produced beta-lactamase (n = 41) were more resistant to trospectomycin, penicillin G, cefoxitin, piperacillin, and tetracycline but not to clindamycin. In this study, trospectomycin had excellent in vitro activity against oral pigmented Bacteroides species.
authors: Department of Medicine, Medical College of Pennsylvania, Philadelphia 19129.
authors: C C
authors: CC
authors: Johnson
authors: M
authors: M
authors: Wendeler
authors: M E
authors: ME
authors: Levison
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001439:Bacteroides / Q000187:drug effects*; D004352:Drug Resistance, Microbial; D008826:Microbial Sensitivity Tests; D000198:Spectinomycin / Q000031:analogs & derivatives* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; C043267:trospectomycin; D000198:Spectinomycin