Characteristics of electrically evoked 'auditory' brainstem responses elicited with the nucleus 22-electrode intracochlear implant.
Electrically evoked auditory brainstem responses (EABRs) were measured in cochlear implant patients fitted with the Nucleus 22 electrode system. The typical response waveform consisted of a series of two to three peaks. The largest peak was similar in form to the wave V of acoustically evoked ABRs and was most prominent for stimulus intensities nearly equal to the patients' maximum comfortable (MC) behavioural stimulus level for the test electrode. The first identifiable wave V amplitude was observed at stimulus levels greater than the patients' psychophysical threshold. With increasing stimulus intensity, wave V amplitude increased rapidly to plateau at a level highly correlated with the patients' MC level at the EABR stimulus rate of 17/s. Wave V peak latency was generally shorter than normal ABRs (4.0 cf. 5.5 ms) and varied with electrode position: apical electrodes had shorter latencies than basal electrodes by approximately 0.4 ms. These results suggest that EABRs can be used as an objective estimate of a patient's electrode-specific MC level, once the correlation of EABR growth functions at 17/s to those at clinically employed rates of 250/s has been determined. EABRs may indicate differences in nerve action potential generation for apical and basal electrodes.
Allum
J H
JH
Department of Otorhinolaryngology, University Clinics, Basel, Switzerland.
Shallop
J K
JK
Hotz
M
M
Pfaltz
C R
CR
D003051:Cochlea; D003054:Cochlear Implants; D003143:Communication Devices for People with Disabilities; D004567:Electrodes, Implanted; D016057:Evoked Potentials, Auditory, Brain Stem; D006801:Humans; D011474:Prosthesis Design; D011930:Reaction Time; D012984:Software