[Studies of rapid detection of drug-resistance of Mycobacterium by gas chromatography].
This test is based on the physiologic character of mycobacterium, which produces carbon dioxide (CO2) during its growth, Löwenstein-Jensen media CO2 contents-were measured by gas chromatography for determining drug-resistance of mycobacteria. This was compared with the routine method. Seventy-eight mycobacteria were isolated from suspected tuberculosis patients for the experiment. Our data suggested that the accordance rates of both methods were 83.3%. Gas chromatography is a simple, rapid and accurate method for detecting drug-resistance. The results can be obtained twenty days earlier than by the routine method.
He
Z
Z
Department of Internal Medicine, Sichuan University.
Li
J
J
Zhao
S
S
Ding
S
S
Wu
L
L
Zhao
Q
Q
D000995:Antitubercular Agents / Q000494:pharmacology*; D002245:Carbon Dioxide / Q000032:analysis; D002849:Chromatography, Gas; D004352:Drug Resistance, Microbial; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000187:drug effects*
D000995:Antitubercular Agents; D002245:Carbon Dioxide