[Immunosuppressive factors in the blood in patients during the development of various kidney diseases].
Sera of patients suffering from Balkan nephropathy, pyelonephritis and glomerulonephritis inhibit lectin-induced T-cell proliferation in vitro. Immunosuppressive factors were registered in the patients' sera during the early stage of the existing disease, and their activity was not in correlation with the degree of renal insufficiency. Serum inhibitors revealed their activity during the early phase of T-cell activation and had no effect on T-cell proliferation and DNK synthesis. Inhibitor activity was registered even if sera were not present in cell culture continuously but only 6 hours of preincubation; then their action was irretrievable.
Dimković
N
N
Institute for Renal Diseases, Zvezdara Clinical and Hospital Centre.
Ramić
Z
Z
Djukanović
Lj
Lj
Trbolević
S
S
Lukić
M
M
D001449:Balkan Nephropathy / Q000276:immunology; D005921:Glomerulonephritis / Q000276:immunology; D006801:Humans; D007674:Kidney Diseases / Q000276:immunology* / Q000628:therapy; D008213:Lymphocyte Activation; D011704:Pyelonephritis / Q000276:immunology; D006435:Renal Dialysis; D013491:Suppressor Factors, Immunologic / Q000097:blood*
D013491:Suppressor Factors, Immunologic
Imunospresivni cinioci u serumu bolesnika tokom evolucije razlicitih bubreznih oboljenja.