Acquired haemophilia.
Two cases of acquired haemophilia A are described. Neither had history of excessive bleeding in the past following operative procedures and both presented with spontaneous bruising as a result of F. VIII:C deficiency due to production of anti-F. VIII:C antibodies. The antibody titre of one case remained unchanged after 4 weeks of therapy with prednisolone and cyclophosphamide. No attempt was made to treat the second case as the antibody titre was very high.
Mehta
J B
JB
Dr J C Patel Department of Haematology, KEM Hospital, Bombay.
Mehta
S
S
D000368:Aged; D000917:Antibody Formation; D003520:Cyclophosphamide / Q000627:therapeutic use; D005169:Factor VIII / Q000276:immunology*; D005260:Female; D006467:Hemophilia A / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use
D003520:Cyclophosphamide; D005169:Factor VIII; D011239:Prednisolone