Comparison of the biosynthesis of the methanobacterial pseudomurein and the eubacterial murein.
From cell extracts of the archaebacterium Methanobacterium thermoautotrophicum 11 putative precursors of the pseudomurein were isolated and characterized. On the basis of the isolated intermediates, a biosynthetic pathway of the pseudomurein is proposed. Compared to the eubacterial murein the biosynthetic stages follow different pathways as indicated by the occurrence of a nucleotide-activated disaccharide and nucleotide-activated peptides.
Hartmann
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E
Abteilung für Angewandte Mikrobiologie und Mykologie der Universität, Ulm, Bundesrepublik Deutschland.
König
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H
D000595:Amino Acid Sequence; D001105:Archaea / Q000235:genetics / Q000378:metabolism*; D001419:Bacteria / Q000235:genetics / Q000378:metabolism*; D002240:Carbohydrate Sequence; D019605:Euryarchaeota / Q000235:genetics / Q000378:metabolism*; D008969:Molecular Sequence Data; D010457:Peptidoglycan / Q000096:biosynthesis*; D010802:Phylogeny
D010457:Peptidoglycan