Hepatobiliary involvement in adolescents and adults with cystic fibrosis.
Fifty nine C.F. pts (38 males) aged 14-41 years have been considered, for all of them the following parameters were taken into account: Shwachman clinical score modified (radiological evaluation emended), steatorrhea, liver function tests (SGOT, SGPT, GT, Bilirubin, AP, Quick T.), A and B hepatitis markers and ultrasonographic scan of pancreas and hepatobiliary system. 23 pts (38%) presented well recognized hepatobiliary involvement: 2 pts (3%) evident cirrhosis, 3 pts (5%) cirrhosis with portal hypertension and esophageal varices, 5 pts (8%) were affected with signs of chronic hepatopathy, 13 pts (22%) presented gallbladder stones.
Quattrucci
S
S
Pediatrics Department, University of Rome La Sapienza, Italy.
Angelico
M
M
Stancati
M
M
Bertasi
S
S
Cantusci
D
D
De Sanctis
A
A
Antonelli
M
M
D000293:Adolescent; D000328:Adult; D002769:Cholelithiasis / Q000150:complications*; D003550:Cystic Fibrosis / Q000150:complications*; D005260:Female; D006801:Humans; D008107:Liver Diseases / Q000150:complications*; D008297:Male