An aberration of fructose metabolism in familial gout identified by 31P magnetic resonance spectroscopy of the liver.
Seegmiller
J E
JE
Department of Biochemistry, John Radcliffe Hospital, Oxford, United Kingdom.
Dixon
R M
RM
Kemp
G J
GJ
Angus
P W
PW
McAlindon
T E
TE
Dieppe
P
P
Rajagopalan
B
B
Radda
G K
GK
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D005260:Female; D005632:Fructose / Q000008:administration & dosage / Q000378:metabolism*; D005634:Fructose-Bisphosphate Aldolase / Q000172:deficiency / Q000235:genetics; D006073:Gout / Q000178:diet therapy / Q000235:genetics / Q000378:metabolism*; D006579:Heterozygote; D006801:Humans; D008099:Liver / Q000378:metabolism; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011687:Purines / Q000378:metabolism; D014527:Uric Acid / Q000097:blood
D004040:Dietary Carbohydrates; D011687:Purines; D014527:Uric Acid; D005632:Fructose; D005634:Fructose-Bisphosphate Aldolase