[The effect of local and systemic immunization of suckling pigs on bronchoalveolar clearance and on intrabronchial infections with Pasteurella multocida].
In vivo investigations of bactericidal bronchoalveolar clearance of weaning pigs locally or systemically immunized with Pasteurella antigens exhibited clearly distinctive results, as early as 3 days after the last immunization. They differed from controls by significant increase in the elimination of the homologous Pasteurella multocida A wild strain. That increase in the clearance remains for 21 days and is specific only to the immunized capsular type. There are no relations of this result to the cytological findings of the lavage fluids and to results of the intrabronchial challenge infection. Frequency and severity of pneumonias were reduced by as little as 3 aerogenic immunizations with Pasteurella mutants.
Müller
G
G
Institut für bakterielle Tierseuchenforschung Jena der Akademie der Landwirtschaftswissenschaften der DDR.
Heilmann
P
P
D000818:Animals; D001428:Bacterial Vaccines; D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology; D010325:Pasteurella / Q000276:immunology*; D010326:Pasteurella Infections / Q000517:prevention & control / Q000662:veterinary*; D011014:Pneumonia / Q000517:prevention & control / Q000662:veterinary*; D013047:Specific Pathogen-Free Organisms; D013552:Swine; D013553:Swine Diseases / Q000517:prevention & control*; D014611:Vaccination / Q000662:veterinary
D001428:Bacterial Vaccines
Der Einfluss lokaler und systemischer Immunisierungen von Läuferschweinen auf die bronchoalveoläre Clearance und auf intrabronchiale Infektionen mit Pasteurella multocida.