The increased plasma Lp(a): B lipoprotein particle concentration in angina pectoris is not associated with hypofibrinolysis.
The structural homology between plasminogen and apolipoprotein (a), the specific glycoprotein of Lp(a) lipoprotein, raises the possibility of a relationship between this lipoprotein and the plasma fibrinolytic system. The present study examines this proposal by studying 66 patients with angina pectoris. As compared to normal controls, the patients had raised concentrations of Lp(a): B lipoprotein particles. No correlation was found between circulating Lp(a): B and the fibrinolytic system. The pathogenic role of Lp(a): B lipoprotein seems therefore not mediated by its effect on the plasma fibrinolytic system.
Alessi
M C
MC
Centre Hospitalier Universitaire Timone, Marseille, France.
Parra
H J
HJ
Joly
P
P
Vu-Dac
N
N
Bard
J M
JM
Fruchart
J C
JC
Juhan-Vague
I
I
D000368:Aged; D000787:Angina Pectoris / Q000097:blood*; D005260:Female; D005342:Fibrinolysis / Q000502:physiology; D006801:Humans; D017270:Lipoprotein(a); D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008875:Middle Aged
D017270:Lipoprotein(a); D008074:Lipoproteins