Immunogenic and protective properties of outer membrane proteins of Hafnia alvei.
Outer membrane proteins (OMP) extracted from antigenically distinct or related strains of Hafnia alvei containing defined composition of major proteins proved to be immunogenic. Intraperitoneal immunization of mice with a single dose of such preparations protected the animals against homologous and heterologous Hafnia strains. The OMP preparations were also found to induce protection with varying intensity against Escherichia, Proteus, Shigella and Salmonella.
Witkowska
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Laboratory of Medical Microbiology, Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław.
Czarny
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Mulczyk
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D000818:Animals; D000942:Antigens, Bacterial / Q000008:administration & dosage; D001425:Bacterial Outer Membrane Proteins / Q000008:administration & dosage / Q000276:immunology*; D004755:Enterobacteriaceae / Q000276:immunology*; D004756:Enterobacteriaceae Infections / Q000517:prevention & control; D004926:Escherichia coli / Q000276:immunology; D007114:Immunization; D051379:Mice; D008815:Mice, Inbred Strains; D011514:Proteus vulgaris / Q000276:immunology; D012486:Salmonella typhimurium / Q000276:immunology; D012763:Shigella flexneri / Q000276:immunology
D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins