[Metronidazole and angina caused by infectious mononucleosis].
Four patients presenting the severe tonsillar form of mononucleosis are reported. Three were male and their age ranged 16 to 19 years. They showed purulent pharyngo-tonsillitis which appeared 7 to 21 days before. Pharyngeal culture failed to show beta hemolytic streptococci in all cases. The patients were treated with metronidazole 250-500 mg/every 8 hours and all experienced a rapid clinical improvement of the oral infection within 36-48 hours with a rapid decrease of the fever. Although the reasons by which metronidazole produces a rapid clinical improvement are not known, administration of this drug in patients with severe tonsillar involvement appears to be useful in the treatment of infectious mononucleosis.
Dalmau
D
D
Servicio de Medicina Interna, Hospital de Mútua de Terrassa, Barcelona.
Travieso
F
F
Sánchez
C
C
Garau
J
J
D000293:Adolescent; D000328:Adult; D001421:Bacteria, Anaerobic / Q000187:drug effects; D001424:Bacterial Infections / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008795:Metronidazole / Q000494:pharmacology / Q000627:therapeutic use*; D010612:Pharyngitis / Q000188:drug therapy* / Q000209:etiology; D015163:Superinfection / Q000188:drug therapy* / Q000209:etiology; D014069:Tonsillitis / Q000188:drug therapy* / Q000209:etiology
D008795:Metronidazole
Metronidazol y angina de la mononucleosis infecciosa.