title: [Results of Visiren administration in patients with respiratory infections].
abstract: One of the most frequent causes of deterioration of chronic obstructive lung diseases is the infection. The existence of microorganisms resistant to antibiotics is becoming an increasingly serious therapeutical problem. Kinolones have a wider spectrum of action than the majority of other antibiotics, with strong effect on multiresistant gram-negative and gram-positive bacteria. Visirene (Ophloxacine) is a new antibiotic in this group. The efficiency of Visirene in the treatment of acute infections of the upper and lower respiratory organs, and acute deterioration or chronic obstructive lung diseases due infections, were investigated. The treatment was carried out on 30 patients in outpatient services. In all patients the appearance and duration of symptoms characteristic for the infection of the respiratory organs were examined (cough, coughing out, increase of body temperature, physical lung findings, dyspnea). The isolation of the causative agent was made from the sputum, throat and nose smears. Medical treatment began only if findings and antibiogram results were positive. The positive effect of Visirene was manifested in rapid withdrawal of symptoms and disappearance of bacteria in the sputum 7-10 day after the beginning of its administration. The administration of the drug provoked no side effects in these thirty patients. All findings suggested a very good effect of Visirene (Ophloxacine) in the treatment of infections of the respiratory system.
authors: Institute for Tuberculosis and Lung Diseases, Belgrade.
authors: Z
authors: Z
authors: Plavsić
authors: M
authors: M
authors: Filipović
authors: D
authors: D
authors: Popovac
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015242:Ofloxacin / Q000627:therapeutic use*; D012141:Respiratory Tract Infections / Q000188:drug therapy*
chemical_list: D015242:Ofloxacin
vernacular_title: Rezultati primene Vizirena kod obolelih od respiracionih infekcija.