title: [Evaluation of the effectiveness of sodium piperacillin in the treatment of surgical infections in children].
abstract: A clinical trial has been carried out in 40 children (age ranging from 2 to 12 years) with postsurgical infections caused by aerobic, anaerobic and facultative bacteria. All have been treated by monotherapy with sodium piperacillin, with doses of 150-200 mg/kg daily in 3 administrations. The drug was administered for a mean period of 7 days, by intravenous infusion or intramuscular route. The causative organism was eradicated in all but 4 cases (90%). Side effects observed were all of mild intensity, and in no case it was necessary to discontinue the treatment with the drug. Both bacterial and clinical results indicate a high tolerability and a very rapid effectiveness of this antibiotic.
authors: Istituto di Ricerca Scientifica, Ospedale Pediatrico Bambin Gesù di Roma.
authors: A
authors: A
authors: Inserra
authors: P
authors: P
authors: Serventi
authors: G
authors: G
authors: Ciprandi
authors: A
authors: A
authors: Spagnoli
authors: S
authors: S
authors: Cristini
authors: C
authors: C
authors: Boglino
mesh_terms: D001424:Bacterial Infections / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D002986:Clinical Trials as Topic; D004334:Drug Administration Schedule; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D010878:Piperacillin / Q000008:administration & dosage / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000188:drug therapy*
chemical_list: D010878:Piperacillin
vernacular_title: Valutazione dell'efficacia della piperacillina sodica nel trattamento delle infezioni chirurgiche pediatriche.