title: 3-(2-carboxyindol-3-yl)propionic acid derivatives: antagonists of the strychnine-insensitive glycine receptor associated with the N-methyl-D-aspartate receptor complex.
authors: Merrell Dow Research Institute, Cincinnati Center, Ohio 45215.
authors: F G
authors: FG
authors: Salituro
authors: B L
authors: BL
authors: Harrison
authors: B M
authors: BM
authors: Baron
authors: P L
authors: PL
authors: Nyce
authors: K T
authors: KT
authors: Stewart
authors: I A
authors: IA
authors: McDonald
mesh_terms: D000818:Animals; D001665:Binding Sites; D001667:Binding, Competitive; D002540:Cerebral Cortex / Q000378:metabolism; D005998:Glycine / Q000378:metabolism*; D006624:Hippocampus / Q000378:metabolism; D007211:Indoles / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology*; D015394:Molecular Structure; D016202:N-Methylaspartate / Q000037:antagonists & inhibitors*; D011422:Propionates / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology*; D051381:Rats; D016194:Receptors, N-Methyl-D-Aspartate / Q000378:metabolism*; D013329:Structure-Activity Relationship; D013331:Strychnine / Q000494:pharmacology*
chemical_list: C000588735:2-carboxy-4,6-dichloro-(1H)-indole-3-propanoic acid; D007211:Indoles; D011422:Propionates; D016194:Receptors, N-Methyl-D-Aspartate; C066275:3-(2-carboxyindol-3-yl)propionic acid; D016202:N-Methylaspartate; D013331:Strychnine; D005998:Glycine