The concept of distinct but voluminous groups of bipolar and unipolar diseases. II. Unipolar diseases.
Seventy-six unipolar affective and 45 unipolar schizoaffective patients were compared using the same instruments as mentioned in part I of this study (this issue). In contrast to bipolar diseases significant differences regarding age at onset were found between the unipolar groups: schizoaffective unipolar patients became ill at a significantly lower age than affective unipolar patients (about 8 years). No other sociodemographic differences were found between the two groups. Patterns of course were found to be similar in both unipolar groups. Unipolar affective patients had a more favourable long-term outcome (GAS and WHO/DAS) than unipolar schizoaffective ones. Altogether, unipolar affective and unipolar schizoaffective disorders seems to have more similarities than differences.
Marneros
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Psychiatric Department, University of Bonn, Federal Republic of Germany.
Rohde
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Deister
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D000203:Activities of Daily Living / Q000523:psychology; D000328:Adult; D001714:Bipolar Disorder / Q000175:diagnosis* / Q000523:psychology; D003866:Depressive Disorder / Q000175:diagnosis* / Q000523:psychology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008016:Life Change Events; D008297:Male; D010552:Personality Assessment; D010554:Personality Disorders / Q000175:diagnosis / Q000523:psychology; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000523:psychology; D012621:Seasons; D012931:Social Environment