Sickle cell hemoglobin, beta-thalassemia and G6PD deficiency in tribes of Maharashtra, India.
The prevalence of sickle cell hemoglobin (HbS), beta-thalassemia trait and G6PD deficiency are reported in some important Gond related endogamous tribes in Maharashtra, India. The HbS gene frequency varies from 0.0530 to 0.1805, the beta-thal gene from 0 to 0.0283 and Gd- gene from 0.0189 to 0.1120. The Pardhan tribe has been identified as a high risk group for sickle cell diseases. Statistically significant differences are observed between tribes.
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Institute of Immunohaematology ICMR, Seth G.S. Medical College, Parel, Bombay, India.
Gorakshakar
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D002648:Child; D002675:Child, Preschool; D005787:Gene Frequency; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000235:genetics*; D006451:Hemoglobin, Sickle / Q000235:genetics*; D006801:Humans; D007194:India; D013789:Thalassemia / Q000235:genetics*
D006451:Hemoglobin, Sickle