Vertical transmission of HBsAg in Alexandria.
A total of 735 pregnant women at delivery and their babies were screened for HBsAg to assess the vertical transmission of HB virus infection. The carrier rate among pregnant women was 5%, evidence of intrauterine transmission reached 8.1% and that of perinatal transmission was 33.3% The most important factors affecting the carrier rate in mothers were the social class, parity, injections, dental manipulation and hospitalization. Nevertheless, among the factors increasing the rate of materno-fetal transmission were the presence of "e" Ag, high titer of HBsAg in mothers serum, cord blood antigenaemia, age of the mother, prolonged duration of labour and breast-feeding.
Farghaly
A G
AG
High Institute of Public Health, Alexandria University.
Hassan
E M
EM
Gawish
S
S
Kotkat
A
A
D002353:Carrier State / Q000276:immunology; D005260:Female; D005312:Fetal Blood / Q000276:immunology; D006509:Hepatitis B / Q000276:immunology / Q000635:transmission*; D006514:Hepatitis B Surface Antigens / Q000097:blood*; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology
D006514:Hepatitis B Surface Antigens