Serum lactate dehydrogenase isoenzymes in breast tumours.
Total serum LDH and its isoenzymes were estimated in 10 female controls and 30 cases of breast lump (22 malignant, 6 benign and 2 breast abscess). In breast malignancy, there was a significant elevation of total LDH and LDH-3, LDH-4 and LDH-5 isoenzymes with a significant fall in LDH-1 and LDH-2 percentage value. Following therapy, there was a significant elevation in LDH-1 and LDH-2 towards normal with a significant fall in total serum LDH and LDH-4 and LDH-5 isoenzymes. The estimation was found to be helpful in assessing the response of patient to the therapy given.
Khurana
P
P
Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University.
Tyagi
N
N
Salahuddin
A
A
Tyagi
S P
SP
D001943:Breast Neoplasms / Q000201:enzymology*; D005260:Female; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000097:blood*
D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase