Pregnancy after transfer of cryopreserved embryos in clomiphene citrate resistant polycystic ovarian syndrome.
Transfer of cryopreserved embryos in PCOS patients resistant to CC stimulation is an intriguing problem. Ovarian stimulation with hMG/hCG to create a secretory endometrium, will entail an unnecessary risk of OHSS. In this case study, we report the accomplishment of a successful pregnancy after transfer of cryopreserved embryos after secretory transformation of the endometrium by E2/P substitution in the absence of corpus luteum formation. However, the success rate of this treatment modality in terms of pregnancy per embryo transfer has still to be evaluated in an ongoing study.
Dale
P O
PO
Department of Gynecology and Obstetrics, National Hospital, University of Oslo, Norway.
Tanbo
T
T
Kjekshus
E
E
Abyholm
T
T
D000328:Adult; D002996:Clomiphene / Q000627:therapeutic use*; D015925:Cryopreservation; D004351:Drug Resistance; D004624:Embryo Transfer; D004958:Estradiol / Q000031:analogs & derivatives / Q000627:therapeutic use; D004966:Estrogens, Conjugated (USP) / Q000627:therapeutic use; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D011085:Polycystic Ovary Syndrome / Q000188:drug therapy / Q000503:physiopathology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*; D011374:Progesterone / Q000627:therapeutic use
D004966:Estrogens, Conjugated (USP); D002996:Clomiphene; D011374:Progesterone; D004958:Estradiol