title: [Primary bladder adenocarcinoma of the signet-ring cell type].
abstract: Primary signet ring cell adenocarcinoma of the bladder is a very uncommon tumor type. Only 20 cases have been reported to date. Two additional cases are described. One patient was diagnosed as having plastic linitis of the bladder. The interval between the onset of symptoms and diagnosis ranged from 2-8 months. Tumor stage was P4 N4 MO and P4 N4 M1 at the time of diagnosis and survival was 3 and 1 month, respectively. This is a tumor with a remarkable intramural proliferation, in the advanced stages at the time of diagnosis, and a poor prognosis. To date, no widely-accepted therapeutic approach has been established.
authors.affiliation: Servicios de Urología y Anatomia Patológica, del Hospital Ramón y Cajal, Madrid, España.
authors.forename: A
authors.initials: A
authors.lastname: Fernández Fernández
authors.forename: E
authors.initials: E
authors.lastname: Maganto Pavón
authors.forename: R
authors.initials: R
authors.lastname: García González
authors.forename: J
authors.initials: J
authors.lastname: Vallejo Serrador
authors.forename: A
authors.initials: A
authors.lastname: Escudero Barrilero
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000175:diagnosis / Q000473:pathology; D000328:Adult; D003951:Diagnostic Errors; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D014401:Tuberculosis, Urogenital / Q000175:diagnosis; D001745:Urinary Bladder Diseases / Q000175:diagnosis; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000473:pathology
vernacular_title: Adenocarcinoma vesical primario tipo células en anillo de sello.