title: [Influence of finger pressing massage on cAMP and cGMP in the cerebrospinal fluid in prolapsed intervertebral disc].
abstract: This paper used RIA method to observe 11 cases of prolapsed intervertebral disc patients, detect the change of cAMP and cGMP in the cerebrospinal fluid before and after finger pressing massage in acupuncture point Weizhong and Chengshan in order to discuss the mechanism of analgesia of finger pressing massage. The results showed that the pain was relieved after finger pressing massage. cAMP of the cerebrospinal fluid increased from 0.51 +/- 0.19 to 0.63 +/- 0.13 pm/ml, in average 32% higher than that before the therapy (P less than 0.05). Since cGMP decreased from 30.52 +/- 26.42 to 23.20 +/- 16.91 pm/ml, it showed that the mechanism of analgesia of finger pressing massage might be due to the fact that the therapy excited selectively endogenous analgesia system, caused the increase of endorphin releasing, and was accompanied by the regulation of cAMP and cGMP.
authors.affiliation: Suzhou Hospital of TCM.
authors.forename: H
authors.initials: H
authors.lastname: Jiang
authors.forename: Z
authors.initials: Z
authors.lastname: Yang
mesh_terms: D015669:Acupuncture Points; D000293:Adolescent; D000328:Adult; D000242:Cyclic AMP / Q000134:cerebrospinal fluid*; D006152:Cyclic GMP / Q000134:cerebrospinal fluid*; D005260:Female; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000134:cerebrospinal fluid / Q000628:therapy*; D008159:Lumbar Vertebrae; D008297:Male; D008405:Massage / Q000379:methods*; D008875:Middle Aged
chemical_list: D000242:Cyclic AMP; D006152:Cyclic GMP