Acute liver failure in a patient with hepatitis A infection on sodium valproate therapy.
An epileptic patient on sodium valproate therapy, who developed acute liver failure following acute hepatitis A infection is reported. The hepatotoxic effects of this drug, and the possibility of intercurrent infection precipitating the toxic effects are discussed.
Harendra de Silva
D G
DG
Faculty of Medicine, University of Ruhuna, Galle.
Keembiyahetty
P
P
Jayantha
U K
UK
Thelisinghe
P U
PU
D000208:Acute Disease; D000293:Adolescent; D056486:Chemical and Drug Induced Liver Injury; D006506:Hepatitis A / Q000188:drug therapy*; D006507:Hepatovirus; D006801:Humans; D008297:Male; D014635:Valproic Acid / Q000009:adverse effects*
D014635:Valproic Acid