[Virilizing ovarian tumor in an adolescent].
This clinical case describes a 13 year-old pubertal girl suffering from secondary virilization, amenorrhea, and abdominal mass. Plasma testosterone and androstenedione levels were markedly elevated. Upon surgery, an ovarian tumor containing 5 l of liquid was removed. The histologic examination revealed a macrocystic granulosa cell type tumor of non-juvenile type. After removal of the tumor, which included ipsilateral ovariectomy, the contralateral ovary developed polycystic changes. The role of the tumoral hyperandrogeny in inducing this contralateral polycystic ovary is discussed.
François
Y
Y
Service de chirurgie, Hôpital Claude-Bernard, Oullins, France.
Berlier
P
P
Chatelain
P
P
François
R
R
D000293:Adolescent; D000728:Androgens / Q000097:blood; D005260:Female; D006106:Granulosa Cell Tumor / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D006801:Humans; D010051:Ovarian Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000378:metabolism / Q000601:surgery; D014770:Virilism / Q000209:etiology*
D000728:Androgens
Tumeur virilisante de l'ovaire chez une adolescente.