title: Duality in the mechanism of action of insulin.
authors.affiliation: Department of Pharmacology, University of Virginia, School of Medicine.
authors.forename: J
authors.initials: J
authors.lastname: Larner
authors.forename: G
authors.initials: G
authors.lastname: Romero
authors.forename: A S
authors.initials: AS
authors.lastname: Kennington
authors.forename: K
authors.initials: K
authors.lastname: Lilley
authors.forename: E
authors.initials: E
authors.lastname: Kilgour
authors.forename: C
authors.initials: C
authors.lastname: Zhang
authors.forename: D
authors.initials: D
authors.lastname: Heimark
authors.forename: G
authors.initials: G
authors.lastname: Gamez
authors.forename: D B
authors.initials: DB
authors.lastname: Houston
authors.forename: L C
authors.initials: LC
authors.lastname: Huang
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D004789:Enzyme Activation / Q000187:drug effects; D019204:GTP-Binding Proteins / Q000502:physiology; D006006:Glycogen Synthase / Q000378:metabolism; D007295:Inositol Phosphates; D007328:Insulin / Q000494:pharmacology* / Q000502:physiology; D009132:Muscles; D010716:Phosphatidylinositols / Q000502:physiology*; D010749:Phosphoprotein Phosphatases / Q000378:metabolism; D010766:Phosphorylation; D011134:Polysaccharides; D011494:Protein Kinases / Q000378:metabolism*; D011499:Protein Processing, Post-Translational / Q000187:drug effects; D011505:Protein-Tyrosine Kinases / Q000502:physiology; D051381:Rats; D011972:Receptor, Insulin / Q000096:biosynthesis / Q000187:drug effects* / Q000502:physiology*; D015398:Signal Transduction; D010738:Type C Phospholipases / Q000502:physiology; D014638:Vanadates / Q000494:pharmacology
chemical_list: D007295:Inositol Phosphates; D007328:Insulin; D010716:Phosphatidylinositols; D011134:Polysaccharides; C028039:inositol phosphate glycan; D014638:Vanadates; D006006:Glycogen Synthase; D011494:Protein Kinases; D011505:Protein-Tyrosine Kinases; D011972:Receptor, Insulin; D010749:Phosphoprotein Phosphatases; D010738:Type C Phospholipases; D019204:GTP-Binding Proteins