[Clinical monitoring and prevention of deep vein thrombosis in an orthopedic department: use of enoxaparin for a year].
Enoxaparin appears in a prospective cooperative study able to provide anti-thrombotic activity in total hip arthroplasty. Consequently during the past year enoxaparin was used routinely to prevent deep vein thrombosis after orthopedic surgery. Clinical results are similar to those obtained with standard subcutaneous heparin followed by oral anticoagulant therapy. Nevertheless after hospital discharge and before full support, risks of oral anticoagulant therapy is to be put in balance with the thrombopenic risk of low molecular weight heparin.
Fluh
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Département d'anesthésie-réanimation, hopital Cochin, Paris.
D004341:Drug Evaluation; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage / Q000627:therapeutic use*; D006622:Hip Prosthesis; D006801:Humans; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D010690:Phlebography; D011446:Prospective Studies; D013923:Thromboembolism / Q000517:prevention & control*; D014812:Vitamin K / Q000037:antagonists & inhibitors
D006495:Heparin, Low-Molecular-Weight; D014812:Vitamin K
Surveillance clinique et prévention des thromboses veineuses profondes dans un service d'orthopédie: un an d'utilisation de l'enoxaparine.