title: Estimation of 24-hour thyroid uptake of I-131 sodium iodide using a 5-minute uptake of technetium-99m pertechnetate.
abstract: The authors have developed a method to estimate the 24-hour sodium iodide thyroid uptake based on a 5-minute Tc-99m pertechnetate thyroid uptake using the equation: Estimated Iodide Uptake = 17.72*In(Pertechnetate Uptake) + 30.40. This estimation has a correlation coefficient of 0.90. It is based on a data pool of 44 patients who underwent I-131 and Tc-99m studies within 2 weeks of each other from 1978-1988, with established diagnoses as follows: 12 euthyroid, 6 hyperthyroid with multinodular goiters, 15 hyperthyroid with diffuse goiters, 4 with subacute thyroiditis, and 7 unknown. The population consisted of 30 women and 14 men with a mean age of 52.0 +/- 17.5 years; this sample was screened for use of thyroid hormone, propylthiouracil, and radiographic contrast. The authors believe this estimation method is of value whenever a 24-hour iodide uptake is desired, and where speed and minimizing radiation dose are factors. This method is strongly recommended for thyroid uptake evaluation before I-131 therapy.
authors.affiliation: Department of Radiology, University of Virginia School of Medicine, Charlottesville.
authors.forename: J J
authors.initials: JJ
authors.lastname: Smith
authors.forename: B Y
authors.initials: BY
authors.lastname: Croft
authors.forename: V A
authors.initials: VA
authors.lastname: Brookeman
authors.forename: C D
authors.initials: CD
authors.lastname: Teates
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007454:Iodides; D007457:Iodine Radioisotopes; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D012974:Sodium Iodide; D013670:Sodium Pertechnetate Tc 99m; D013960:Thyroid Function Tests / Q000379:methods*; D013961:Thyroid Gland / Q000000981:diagnostic imaging* / Q000502:physiology / Q000503:physiopathology; D013997:Time Factors
chemical_list: D007454:Iodides; D007457:Iodine Radioisotopes; D013670:Sodium Pertechnetate Tc 99m; D012974:Sodium Iodide