title: Abolition of herpes simplex cytopathic effect after treatment with peroxidase generated hypothiocyanite.
abstract: HSV1 suspensions were pre-incubated in a lactoperoxidase thiocyanate oxidizing system before inoculation in MRC5 fibroblast cultures. This pre-treatment could either delay or even abolish the HSV1 cytopathic potentiality. The effect was found to be time-dependent.
authors.affiliation: Laboratoire de Stomatologie, Université Libre de Bruxelles, Faculté de Medecine, Belgique.
authors.forename: P
authors.initials: P
authors.lastname: Courtois
authors.forename: D
authors.initials: D
authors.lastname: van Beers
authors.forename: M
authors.initials: M
authors.lastname: de Foor
authors.forename: I M
authors.initials: IM
authors.lastname: Mandelbaum
authors.forename: M
authors.initials: M
authors.lastname: Pourtois
mesh_terms: D000998:Antiviral Agents; D002460:Cell Line; D005347:Fibroblasts / Q000502:physiology; D006801:Humans; D007784:Lactoperoxidase / Q000494:pharmacology*; D010084:Oxidation-Reduction; D018139:Simplexvirus / Q000187:drug effects* / Q000502:physiology; D013861:Thiocyanates / Q000494:pharmacology*; D013997:Time Factors
chemical_list: D000998:Antiviral Agents; D013861:Thiocyanates; C024553:sodium thiocyanate; D007784:Lactoperoxidase; C031760:thiocyanate