title: [The rickettsial genome studied by DNA restriction analysis].
abstract: The restriction analysis of 6 Rickettsia prowazekii strains with the use of 8 restrictases (Cfr13I, EcoRI, HindIII, MSpI, MvaI, PstI, XhoI, BamHI) has been carried out. In the presence of considerable homology in the restriction pictures of DNA in these strains some differences in 1-2 fragments within the range of 8,000-20,000 nucleotide pairs have been established. The strains under study have been divided into two groups according to the character of differences in their restrictograms: the group of virulent typing strain Breinl (Breinl, G. Anan'ev) and the group of strain E with low pathogenicity (E, EVir, Katsinian). Differences in the restrictograms of DNA do not correlate with the virulence of R. prowazekii strains and the areas of their isolation.
authors.forename: E B
authors.initials: EB
authors.lastname: Rydkina
authors.forename: M I
authors.initials: MI
authors.lastname: Artem'ev
authors.forename: N M
authors.initials: NM
authors.lastname: Balaeva
authors.forename: V F
authors.initials: VF
authors.lastname: Ignatovich
authors.forename: V V
authors.initials: VV
authors.lastname: Demkin
mesh_terms: D004262:DNA Restriction Enzymes / Q000494:pharmacology; D004269:DNA, Bacterial / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D005798:Genes, Bacterial / Q000187:drug effects / Q000235:genetics*; D015183:Restriction Mapping; D012283:Rickettsia prowazekii / Q000187:drug effects / Q000235:genetics* / Q000472:pathogenicity; D014774:Virulence / Q000187:drug effects / Q000235:genetics
chemical_list: D004269:DNA, Bacterial; D004262:DNA Restriction Enzymes
vernacular_title: Izuchenie genoma rikketsiĭ metodom restriktsionnogo analiza DNK.