title: Parvovirus B19-associated hemophagocytic syndrome.
abstract: Parvovirus B19 is a recently described pathogen, associated with an increasing spectrum of clinical manifestations. We present the first reported case, to our knowledge, of parvovirus B19-associated hemophagocytic syndrome, in which the diagnosis of parvovirus infection was documented by the presence of B19-specific IgM and IgG antibodies. Pancytopenia resolved immediately following splenectomy and the patient recovered completely.
authors.affiliation: Department of Medicine, University of Massachusetts Medical Center, Worcester 01655.
authors.forename: S E
authors.initials: SE
authors.lastname: Boruchoff
authors.forename: B A
authors.initials: BA
authors.lastname: Woda
authors.forename: G A
authors.initials: GA
authors.lastname: Pihan
authors.forename: W A
authors.initials: WA
authors.lastname: Durbin
authors.forename: D
authors.initials: D
authors.lastname: Burstein
authors.forename: N R
authors.initials: NR
authors.lastname: Blacklow
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis; D002648:Child; D015616:Histiocytosis, Non-Langerhans-Cell / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008297:Male; D010321:Parvoviridae / Q000302:isolation & purification; D010322:Parvoviridae Infections / Q000175:diagnosis* / Q000473:pathology; D013154:Spleen / Q000473:pathology
chemical_list: D000914:Antibodies, Viral