Inhibitors of bombesin-stimulated intracellular signals: interruption of an autocrine pathway as a therapeutic strategy in small cell lung carcinoma.
Sausville
E A
EA
NCI-Navy Medical Oncology Branch, Bethesda, MD.
Trepel
J B
JB
Moyer
J D
JD
D001839:Bombesin / Q000037:antagonists & inhibitors*; D018288:Carcinoma, Small Cell / Q000503:physiopathology / Q000628:therapy*; D004533:Egtazic Acid / Q000494:pharmacology; D006801:Humans; D008175:Lung Neoplasms / Q000503:physiopathology / Q000628:therapy*; D010716:Phosphatidylinositols / Q000378:metabolism; D018004:Receptors, Bombesin; D017981:Receptors, Neurotransmitter / Q000187:drug effects; D015398:Signal Transduction / Q000187:drug effects*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D014407:Tumor Cells, Cultured
D010716:Phosphatidylinositols; D018004:Receptors, Bombesin; D017981:Receptors, Neurotransmitter; D004533:Egtazic Acid; D001839:Bombesin