title: Potential mechanisms of resistance to the modern fluorinated 4-quinolones.
authors.affiliation: Department of Bacteriology, Medical School, Edinburgh University.
authors.forename: C S
authors.initials: CS
authors.lastname: Lewin
authors.forename: R A
authors.initials: RA
authors.lastname: Allen
authors.forename: S G
authors.initials: SG
authors.lastname: Amyes
mesh_terms: D042462:4-Quinolones; D000890:Anti-Infective Agents / Q000493:pharmacokinetics / Q000494:pharmacology*; D002463:Cell Membrane Permeability; D004250:DNA Topoisomerases, Type II / Q000235:genetics*; D004352:Drug Resistance, Microbial; D004754:Enterobacter / Q000187:drug effects / Q000378:metabolism; D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism*; D007709:Klebsiella / Q000187:drug effects / Q000378:metabolism; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000235:genetics; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000378:metabolism*; D012705:Serratia / Q000187:drug effects / Q000378:metabolism
chemical_list: D042462:4-Quinolones; D000890:Anti-Infective Agents; D004250:DNA Topoisomerases, Type II