[Course of pregnancy following in vitro fertilization and embryo transfer].
Worldwide analysis of pregnancies after IVF/ET allows the evaluation of the pregnancy outcome compared to normal population. The mean age of IVF-patients is significantly higher. The incidence of clinical abortions after IVF/ET is within normal range, correlating rather with age than with treatment modalities. The rate of multiple gestations is increased after IVF/ET as well as GIFT or hMG-stimulation, leading to more high risk pregnancies. Gestosis is seen in 7% of singletons and 17% of triplet pregnancies. Preterm deliveries before 36 weeks of gestation occur in 17% of singleton and 52% of twin pregnancies after IVF/ET (control 7.3%). This leads to an increasing rate of caesarean section. The global malformation rate is 2% and in a comparable range to normal population. A presumably higher incidence of neural tube defects has to be proven in a larger number of IVF pregnancies.
Wiedemann
R
R
Ludwig-Maximilians-Universität München, Universitäts-Frauenklinik im Klinikum Grosshadern.
Korell
M
M
Strowitzki
T
T
Hepp
H
H
D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology*; D011256:Pregnancy Outcome; D012307:Risk Factors
Schwangerschaftsverlauf nach In-vitro-Fertilisation und Embryotransfer.