title: Detoxification of alcoholics: improving care by symptom-triggered sedation.
abstract: This study evaluated a staff training program on alcohol detoxification. Training consisted of didactic presentations on the pathophysiology of alcohol withdrawal syndrome and information on use of the Clinical Institute Withdrawal Assessment for Alcohol (CIWA-A). Treatment course was assessed on 100 patients admitted before or after the training. Whereas 73% of patients were given drug therapy before, only 13% of patients received drug therapy after. Significantly more benzodiazepine was administered before training (M = 108.48 mg) than after training (M = 42.97 mg). After excluding those who received no drug therapy, patients who received benzodiazepine after the training received significantly higher amounts of benzodiazepine (M = 252.50 mg) than those who received drug before (M = 144.64 mg). The average number of hours from the first benzodiazepine dose to the last was reduced from 13 to 5 hr. Clinical implications of matching patient symptomatology with appropriate drug therapy, thus preventing both over- and under-treatment for alcohol withdrawal symptoms, are discussed.
authors.affiliation: Substance Abuse Treatment Center, Roger Williams General Hospital, Providence, RI 02908.
authors.forename: A A
authors.initials: AA
authors.lastname: Wartenberg
authors.forename: T D
authors.initials: TD
authors.lastname: Nirenberg
authors.forename: M R
authors.initials: MR
authors.lastname: Liepman
authors.forename: L Y
authors.initials: LY
authors.lastname: Silvia
authors.forename: A M
authors.initials: AM
authors.lastname: Begin
authors.forename: P M
authors.initials: PM
authors.lastname: Monti
mesh_terms: D000437:Alcoholism / Q000523:psychology / Q000534:rehabilitation*; D002707:Chlordiazepoxide / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy* / Q000451:nursing / Q000503:physiopathology
chemical_list: D002707:Chlordiazepoxide