Toward an understanding of the dihydropyridine-sensitive calcium channel.
The dihydropyridine-sensitive calcium channel continues to fascinate scientific investigators. Each new discovery leads to more complexity. Further work elucidating the molecular structures and functions of the various isoforms of the channel will lead us to a better understanding of its nature. We are well on our way towards understanding the molecular structure and mechanisms involved in calcium permeability, and the coming decade promises to reveal numerous breakthroughs in our understanding of this channel.
McKenna
E
E
Department of Pharmacology and Cell Biophysics, University of Cincinnati Medical Center, OH 45267-0575.
Koch
W J
WJ
Slish
D F
DF
Schwartz
A
A
D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D015220:Calcium Channels / Q000187:drug effects* / Q000378:metabolism / Q000648:ultrastructure; D004095:Dihydropyridines / Q000494:pharmacology*; D008565:Membrane Proteins / Q000378:metabolism*; D008969:Molecular Sequence Data; D009130:Muscle, Smooth / Q000378:metabolism; D009132:Muscles / Q000378:metabolism*; D009626:Terminology as Topic
D015220:Calcium Channels; D004095:Dihydropyridines; D008565:Membrane Proteins; C038806:1,4-dihydropyridine