A serological comparison of some animal herpesviruses.
Bovine herpesvirus 1 (BHV-1) isolates (Cooper-type strain 4975 and Oxford) were compared in neutralization tests with the bovine herpesvirus 4 (BHV-4) isolate (85/16 TV) and the herpesviruses of red deer (D2839/1) and goats (E/CH). Hyperimmune antiserum was prepared in rabbits against the plaque-selected viruses and endpoint and kinetic neutralization test were made. BHV-4 was clearly different from the other four viruses. The closely-related BHV-1 strains were also related in these tests to the red deer herpesvirus. The Oxford strain seemed rather closer antigenically than the Cooper-type strain to the red deer herpesvirus. Antiserum to the caprine herpesvirus failed to neutralize either BHV-1 strain or red deer virus, but antiserum to the Cooper-type and red deer herpesviruses did neutralize caprine virus to a limited extent.
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"Vittorio Cilli" University Laboratory of Virology, School of Veterinary Medicine, University of Perugia, Italy.
Castrucci
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Frigeri
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Ferrari
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D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D000956:Antigens, Viral / Q000276:immunology*; D002417:Cattle; D003670:Deer; D006041:Goats; D006564:Herpesviridae / Q000254:growth & development / Q000276:immunology*; D007242:Herpesvirus 1, Bovine / Q000254:growth & development / Q000276:immunology*; D007106:Immune Sera / Q000276:immunology; D007700:Kinetics; D009500:Neutralization Tests; D010948:Viral Plaque Assay
D000914:Antibodies, Viral; D000956:Antigens, Viral; D007106:Immune Sera