title: [The study on Chinese herbal medicinal prescription with enzyme inhibitory activity. III. The study of mao-to with adenosine 3',5'-cyclic monophosphate phosphodiesterase].
abstract: Mao-to, a Chinese herbal medicinal prescription was studied for the inhibitory activity of adenosine 3',5'-cyclic monophosphate (cAMP) phosphodiesterase. The inhibitory activity for this enzyme depended mainly on Ephedra herb and Glycyrrhiza in this prescription. Apricot kennel acted as a mitigatory component for Ephedra herb in cAMP phosphodiesterase inhibitory test. In ephedrine and the related compounds the inhibitory activity of cAMP phosphodiesterase was not shown.
authors.affiliation: Toho University, School of Pharmaceutical Sciences, Chiba, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Nikaido
authors.forename: T
authors.initials: T
authors.lastname: Ohmoto
authors.forename: T
authors.initials: T
authors.lastname: Kuge
authors.forename: A
authors.initials: A
authors.lastname: Yanagisawa
authors.forename: K
authors.initials: K
authors.lastname: Teinozawa
authors.forename: H
authors.initials: H
authors.lastname: Takeda
authors.forename: H
authors.initials: H
authors.lastname: Tsukamoto
mesh_terms: D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000037:antagonists & inhibitors*; D004339:Drug Compounding; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*
chemical_list: D004365:Drugs, Chinese Herbal; D015105:3',5'-Cyclic-AMP Phosphodiesterases