Psychoneuroimmunology and HIV-1.
Recent psychoneuroimmunologic findings have suggested that it may be useful to evaluate the influence of behavioral factors on immune functioning and disease progression among human immunodeficiency virus-Type 1 (HIV-1) infected individuals. Behavioral interventions with immunomodulatory capabilities may help restore competence and thereby arrest HIV-1 disease promotion at the earliest stages of the infectious continuum. Evidence describing benefits of behavioral interventions such as aerobic exercise training on both psychological and immunological functioning among high-risk HIV-1 seronegative and very early stage seropositive gay men is presented. The HIV-1 infection is cast as a chronic disease for which early immunomodulatory behavioral interventions may have important physical and psychological impact.
Antoni
M H
MH
Center for the Biopsychosocial Study of AIDS, University of Miami, Coral Gables, Florida 33124.
Schneiderman
N
N
Fletcher
M A
MA
Goldstein
D A
DA
Ironson
G
G
Laperriere
A
A
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000276:immunology / Q000523:psychology*; D001007:Anxiety / Q000209:etiology / Q000628:therapy; D003863:Depression / Q000209:etiology / Q000628:therapy; D005081:Exercise Therapy; D015497:HIV-1; D006801:Humans; D013315:Stress, Psychological / Q000209:etiology*; D013601:T-Lymphocytes / Q000276:immunology