title: The spin trapping of superoxide with M4PO (3,3,5,5-tetramethylpyrroline-N-oxide).
abstract: The spin trap 3,3,5,5-tetramethylpyrroline-N-oxide (M4PO) reacts with superoxide to produce a short-lived spin adduct (M4PO/.OOH, AN = 14.0 G, AH = 6.5 G) that decays by a first-order process (t1/2 approximately 35 s at pH 7.4). This short lifetime may limit its usefulness in studies of superoxide.
authors.affiliation: ESR Center, University of Iowa, Iowa City 52242.
authors.forename: G R
authors.initials: GR
authors.lastname: Buettner
authors.forename: B E
authors.initials: BE
authors.lastname: Britigan
mesh_terms: D003497:Cyclic N-Oxides; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals; D006878:Hydroxides; D017665:Hydroxyl Radical; D013113:Spin Labels; D013481:Superoxides / Q000032:analysis*
chemical_list: D003497:Cyclic N-Oxides; D005609:Free Radicals; D006878:Hydroxides; D013113:Spin Labels; C051831:3,3,5,5-tetramethyl-1-pyrroline N-oxide; D013481:Superoxides; D017665:Hydroxyl Radical; C017245:5,5-dimethyl-1-pyrroline-1-oxide