A pilot study investigating intraoperative electron beam irradiation in the treatment of ovarian malignancies.
Intraoperative electron beam radiation therapy (IOEBRT) in the treatment of ovarian malignancies was investigated at the Clement O. Miniger Radiation Oncology Center (COMROC). Nine patients were operated in the COMROC IOEBRT operating amphitheater and five were found to have disease sufficiently limited to allow for IOEBRT. The patients' ages ranged from 13 to 80 (median 53) years. Five patients had serous cystadenocarcinoma, one papillary adenocarcinoma, one mixed germ cell tumor, one squamous cell carcinoma, and one granular cell tumor of the ovary. The median survival of the non-IOEBRT group was 13 (range 12-29) months, while the IOEBRT group's median survival was 14 (range 18-46) months. All of the patients tolerated IOEBRT well without addition to the surgical morbidity.
Konski
A A
AA
Department of Radiation Therapy, Medical College of Ohio, Toledo 43614.
Neisler
J
J
Phibbs
G
G
Bronn
D G
DG
Dobelbower
R R
RR
D000231:Adenocarcinoma, Papillary / Q000532:radiotherapy; D000293:Adolescent; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy; D003536:Cystadenocarcinoma / Q000532:radiotherapy; D004583:Electrons; D005260:Female; D006801:Humans; D007430:Intraoperative Care; D008875:Middle Aged; D009373:Neoplasms, Germ Cell and Embryonal / Q000532:radiotherapy; D009379:Neoplasms, Muscle Tissue / Q000532:radiotherapy; D010051:Ovarian Neoplasms / Q000453:epidemiology / Q000532:radiotherapy*; D010865:Pilot Projects; D012189:Retrospective Studies; D016019:Survival Analysis