[The combined treatment of lung cancer with one-time large-fraction preoperative irradiation].
A procedure of preoperative large single dose (7.5 Gy) irradiation of lung cancer was developed. Irradiation field included regional lymph node-bearing areas. Treatment was employed in 93 lung cancer patients. Postoperative complication and lethality rates were 14 and 2.2%, respectively. Patients presenting with metastases in the regional lymph nodes were postoperatively irradiated to the lung hilus and mediastinum (30 Gy in 10 fractions). The treatment was well tolerated. Eighty-eight patients were followed, of whom 43.3% survived 3 years. The above modality assured ablastics of surgery and allowed to minimize duration of preoperative radiotherapy.
Kharchenko
V P
VP
Galil-Ogly
G A
GA
Chkhikvadze
V D
VD
Pan'shin
G A
GA
Goncharova
I M
IM
Sotnikov
V M
VM
D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D000328:Adult; D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D003131:Combined Modality Therapy; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009367:Neoplasm Staging; D011013:Pneumonectomy / Q000379:methods; D011183:Postoperative Complications / Q000453:epidemiology; D011300:Preoperative Care / Q000379:methods*; D011879:Radiotherapy Dosage
Kombinirovannoe lechenie raka legkogo s odnokratnym krupnofraktsionnym predoperatsionnym oblucheniem.