Infection of chimpanzees with the Uganda I/CDC strain of Plasmodium malariae.
Nine splenectomized chimpanzees were infected with the Uganda I/CDC strain of Plasmodium malariae. Two had no history of previous malarial infection, whereas 6 had been infected with P. vivax and 1 with P. vivax and P. ovale. The animals with no previous infection had maximum parasitemias of 8,740 and 10,800/mm3. The other animals had maximum parasite counts of 930-75,700/mm3. Anopheles freeborni, An. stephensi, An. dirus, An. maculatus, An. quadrimaculatus, An. culicifacies, An. arabiensis, and An. gambiae were readily infected by feeding through membranes on heparinized blood from these animals.
Collins
W E
WE
Division of Parasitic Diseases, Centers for Disease Control, Atlanta, Georgia.
McClure
H M
HM
Strobert
E
E
Filipski
V
V
Skinner
J C
JC
Stanfill
P S
PS
Richardson
B B
BB
Morris
C
C
D000818:Animals; D000852:Anopheles / Q000469:parasitology*; D007303:Insect Vectors / Q000469:parasitology*; D008288:Malaria / Q000097:blood / Q000469:parasitology* / Q000635:transmission; D002679:Pan troglodytes / Q000469:parasitology*; D010965:Plasmodium malariae / Q000502:physiology*; D013156:Splenectomy