Angiotensin-converting enzyme distribution and hypoxia response in mammal, bird, and fish.
Angiotensin I-converting enzyme activity was measured in homogenates of guinea pig (Cavia porcellus), chicken (Gallus domesticus), and carp (Cyprinus carpio) organs. The highest activity was found in guinea pig lung and chicken kidney. In carp the highest activity was found in heart and spleen, although gill arch also showed a high activity. Acute hypoxia decreased the angiotensin I-converting enzyme activity in guinea pig lung and carp gill arch, but the changes in chicken lung and kidney were considered nonsignificant.
Polanco
M J
MJ
Departamento de Bioquímica, Biología Molecular y Fisiología, Facultad de Ciencias, Universidad de Valladolid, Spain.
Mata
M I
MI
Agapito
M T
MT
Recio
J M
JM
D000595:Amino Acid Sequence; D000818:Animals; D002347:Carps; D002645:Chickens; D005880:Gills / Q000201:enzymology; D006168:Guinea Pigs; D000860:Hypoxia / Q000378:metabolism*; D007668:Kidney / Q000201:enzymology; D008168:Lung / Q000201:enzymology; D008969:Molecular Sequence Data; D009206:Myocardium / Q000201:enzymology; D007703:Peptidyl-Dipeptidase A / Q000378:metabolism*; D013045:Species Specificity; D013154:Spleen / Q000201:enzymology; D014018:Tissue Distribution
D007703:Peptidyl-Dipeptidase A