Glucose metabolism in a patient with insulinoma complicated by hyperosmolar non-ketotic state.
A case of a patient with organic hyperinsulinism complicated by the development of hyperosmolar state is described. The hyperosmolar state was induced by vomiting and dehydration during an acute urinary tract infection. Impairment of glucose metabolism was confirmed by the finding of reduced tissue sensitivity to insulin during a euglycaemic clamp.
Skrha
J
J
Department of Internal Medicine 3, Faculty of Medicine, Charles University, Prague, Czechoslovakia.
Páv
J
J
Svacina
S
S
Srámková
J
J
Hilgertová
J
J
D007516:Adenoma, Islet Cell / Q000097:blood*; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism*; D003926:Diabetic Coma / Q000097:blood*; D004573:Electrolytes / Q000097:blood; D015309:Glucose Clamp Technique; D005951:Glucose Tolerance Test; D006801:Humans; D006944:Hyperglycemic Hyperosmolar Nonketotic Coma / Q000097:blood* / Q000150:complications; D007340:Insulinoma / Q000097:blood* / Q000150:complications; D008297:Male; D010190:Pancreatic Neoplasms / Q000097:blood* / Q000150:complications
D001786:Blood Glucose; D004573:Electrolytes