[MR-tomographic quantification of infiltrative bone marrow changes and therapeutic follow-up of patients with hairy cell leukemia].
The effect of treatment on bone marrow infiltration in hairy cell leukaemia was followed by means of MRT in five patients. A semi-quantitative method has been developed in order to judge the effect of treatment. The results correlate well with the findings on iliac crest biopsies. The method could partly replace the invasive iliac crest biopsies, which are used for therapy monitoring.
Gückel
F
F
Institut für Radiologie und Pathophysiologie des Deutschen Krebsforschungszentrums, Heidelberg.
Semmler
W
W
Knauf
W
W
Brix
G
G
Ho
A D
AD
van Kaick
G
G
D001853:Bone Marrow / Q000473:pathology*; D005260:Female; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use; D007943:Leukemia, Hairy Cell / Q000188:drug therapy*; D008279:Magnetic Resonance Imaging; D008297:Male; D008991:Monitoring, Physiologic / Q000379:methods*; D015649:Pentostatin / Q000627:therapeutic use
D007370:Interferon Type I; D015649:Pentostatin
MR-tomographische Quantifizierung von infiltrativen Knochenmarkveränderungen und Therapie- verlaufskontrolle bei Patienten mit Haarzell-Leukämie.