title: Inhibitors of bombesin-stimulated intracellular signals: interruption of an autocrine pathway as a therapeutic strategy in small cell lung carcinoma.
authors.affiliation: NCI-Navy Medical Oncology Branch, Bethesda, MD.
authors.forename: E A
authors.initials: EA
authors.lastname: Sausville
authors.forename: J B
authors.initials: JB
authors.lastname: Trepel
authors.forename: J D
authors.initials: JD
authors.lastname: Moyer
mesh_terms: D001839:Bombesin / Q000037:antagonists & inhibitors*; D018288:Carcinoma, Small Cell / Q000503:physiopathology / Q000628:therapy*; D004533:Egtazic Acid / Q000494:pharmacology; D006801:Humans; D008175:Lung Neoplasms / Q000503:physiopathology / Q000628:therapy*; D010716:Phosphatidylinositols / Q000378:metabolism; D018004:Receptors, Bombesin; D017981:Receptors, Neurotransmitter / Q000187:drug effects; D015398:Signal Transduction / Q000187:drug effects*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D014407:Tumor Cells, Cultured
chemical_list: D010716:Phosphatidylinositols; D018004:Receptors, Bombesin; D017981:Receptors, Neurotransmitter; D004533:Egtazic Acid; D001839:Bombesin