Renin production by nephroblastoma cells in culture.
Nephroblastoma cells have been cultured for 19 days. During this time cell growth and active and inactive renin secretion were monitored. Inactive renin was found to be secreted in excess of active renin. The main secretory protein, precipitated with antirenin IgG was found to have a molecular mass of 52,000 daltons.
Inglis
G C
GC
MRC Blood Pressure Unit, Western Infirmary, Glasgow, Scotland.
Leckie
B J
BJ
D002455:Cell Division; D006801:Humans; D007680:Kidney Neoplasms / Q000201:enzymology* / Q000378:metabolism / Q000473:pathology; D008970:Molecular Weight; D012083:Renin / Q000032:analysis / Q000096:biosynthesis* / Q000378:metabolism; D014407:Tumor Cells, Cultured / Q000201:enzymology / Q000378:metabolism / Q000473:pathology; D009396:Wilms Tumor / Q000201:enzymology* / Q000378:metabolism / Q000473:pathology
D012083:Renin