title: Results of breast conserving treatment of breast cancer.
abstract: Between 1978 and 1985, 247 patients with primary breast cancer have been treated with breast conserving surgery and external beam radiotherapy. Median follow-up is 3 years and 9 months. Actuarial 5-year disease-free survival for the whole group is 72%; 16 patients (6.8%) have relapsed in the breast to date. Of these, 6 (38%) have died from breast cancer. Patients who have experienced a local recurrence have significantly worse survival than those who remain locally recurrence-free (p less than 0.001). Complication data are presented and shown to be almost entirely mild to moderate and in the range 1-19%. This series shows the breast conserving approach to be effective and at least equivalent to breast ablative procedures in early follow-up.
authors.affiliation: Institute of Oncology and Radiotherapy, Prince of Wales Hospital, Randwick, NSW, Australia.
authors.forename: C S
authors.initials: CS
authors.lastname: Hamilton
authors.forename: J M
authors.initials: JM
authors.lastname: Nield
authors.forename: G F
authors.initials: GF
authors.lastname: Adler
authors.forename: P R
authors.initials: PR
authors.lastname: Clingan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001315:Australia; D001943:Breast Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D015996:Survival Rate