title: Effects of REM sleep deprivation of ACTH-induced yawning.
abstract: Central administration of ACTH in rats induces yawning and stretching. In order to study the effects of REM sleep deprivation on ACTH-induced yawning, the peptide was injected immediately after the REM sleep deprivation period or 24 h later. REM sleep deprivation impaired ACTH-induced yawning, but after a 24-hour recovery period, rats displayed a number of yawns similar to those in control animals. Implications for an involvement of dopaminergic and mainly cholinergic systems are discussed.
authors.affiliation: Department of Psychobiology, Escola Paulista de Medicina, São Paulo, Brazil.
authors.forename: L L
authors.initials: LL
authors.lastname: Lobo
authors.forename: B G
authors.initials: BG
authors.lastname: Neumann
authors.forename: D S
authors.initials: DS
authors.lastname: Eidman
authors.forename: S
authors.initials: S
authors.lastname: Tufik
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D003366:Cosyntropin / Q000494:pharmacology; D007276:Injections, Intraventricular; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D012895:Sleep, REM / Q000187:drug effects / Q000502:physiology*; D015000:Yawning / Q000187:drug effects*
chemical_list: D003366:Cosyntropin; D000324:Adrenocorticotropic Hormone