High voltage redox properties of cytochrome c oxidase.
In earlier studies evidence was obtained for the existence of both high and low redox potential forms of cytochrome a3 (Hendler et al. 1986. Biophys. J. 49:717-729; Hendler and Sidhu. 1988. Biophys. J. 54:121-133). The current paper describes additional experiments that support this conclusion and then reviews a large number of experimental observations that appear to be consistent with the view that cytochrome a3 displays at least (see Sidhu and Hendler. 1990. Biophys. J. 57:1125-1140) two different forms, which are distinguishable by their redox potentials, spectra, and reactivity with CO.
Hendler
R W
RW
Laboratory of Cell Biology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892.
Sidhu
G S
GS
Pardhasaradhi
K
K
D055592:Biophysical Phenomena; D001703:Biophysics; D003486:Cyanides; D017936:Cytochrome a Group; D003580:Cytochromes; D004563:Electrochemistry; D004579:Electron Transport; D003576:Electron Transport Complex IV / Q000737:chemistry / Q000378:metabolism*; D004734:Energy Metabolism; D009570:Nitriles; D010084:Oxidation-Reduction; D010777:Photochemistry; D013053:Spectrophotometry
D003486:Cyanides; D017936:Cytochrome a Group; D003580:Cytochromes; D009570:Nitriles; C011206:cyanogen; D003576:Electron Transport Complex IV