Undifferentiated carcinoma with lymphoid stroma of the major salivary glands.
Undifferentiated carcinoma with lymphoid stroma or lymphoepithelial carcinoma of the major salivary glands is a demographically and histopathologically unique malignancy. Although whites may have the disease, it is preponderantly a carcinoma of North American Eskimos and native Greenlanders. The carcinoma shares many features with undifferentiated nasopharyngeal carcinomas, from which it must be distinguished: histologic appearance, putative relationship with Epstein-Barr virus, predilection for mongoloid races, and response to therapy. In some cases, the carcinoma appears to have evolved from a lymphoepithelial lesion.
Cleary
K R
KR
Division of Pathology, University of Texas M.D. Anderson Cancer Center, Houston 77030.
Batsakis
J G
JG
D000328:Adult; D002277:Carcinoma / Q000208:ethnology / Q000473:pathology* / Q000556:secondary; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012307:Risk Factors; D012468:Salivary Gland Neoplasms / Q000208:ethnology / Q000473:pathology*