title: Surveillance of viral respiratory tract infections over a one year period in mainly hospitalized Austrian infants and children by a rapid enzyme-linked immunosorbent assay diagnosis.
abstract: In order to obtain more information on viral respiratory tract infections in Austrian infants and children, nasopharyngeal secretions from 1432 infants and children, collected from October 1984 to October 1985, were screened for the presence of respiratory syncytial virus (RSV), adenoviruses, parainfluenza virus type 1, 2, and 3, and influenza viruses type A and B, by enzyme-linked immunosorbent assay (ELISA). The results obtained were analyzed with respect to incidence, seasonal distribution and clinical syndromes associated with the different viral pathogens investigated and also with the practicability of ELISA diagnostics over long distances. A viral etiology of acute respiratory tract infection was confirmed in 372 (26%) infants. RSV was detected in 286 (20%) of the nasal secretions and was thus the most frequently encountered agent. RSV infections occurred mainly in the winter months and were often associated with bronchitis, bronchiolitis, and pneumonia. Only sporadic infections were found with one of the other viruses investigated.
authors.affiliation: Institute of Virology, University of Vienna.
authors.forename: G
authors.initials: G
authors.lastname: Kellner
authors.forename: T
authors.initials: T
authors.lastname: Popow-Kraupp
authors.forename: C
authors.initials: C
authors.lastname: Popow
authors.forename: M
authors.initials: M
authors.lastname: Kundi
authors.forename: C
authors.initials: C
authors.lastname: Kunz
mesh_terms: D000260:Adenoviruses, Human / Q000302:isolation & purification; D001317:Austria / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009305:Nasopharynx / Q000382:microbiology; D009975:Orthomyxoviridae / Q000302:isolation & purification; D011159:Population Surveillance; D012136:Respiratory Syncytial Viruses / Q000302:isolation & purification; D012141:Respiratory Tract Infections / Q000453:epidemiology / Q000382:microbiology*; D018108:Respirovirus / Q000302:isolation & purification; D012189:Retrospective Studies; D012621:Seasons; D014777:Virus Diseases / Q000453:epidemiology / Q000382:microbiology*