title: [A case of brain metastasis from breast cancer responding to chemoendocrine therapy].
abstract: Brain metastasis is one of the most critical metastatic lesion on the treatment of breast cancer. We reported a case with brain metastasis from breast cancer responding to chemoendocrine therapy. The patient was 71 years old female complaining gait disturbance. Solitary brain metastasis and multiple bone metastases of breast cancer were diagnosed by CT scan and bone scintigram. Standard radical mastectomy was done. Estrogen receptor was proved to be positive in both of the tumor and metastatic lymph node. Tamoxifen and UFT were administered as chemoendocrine therapy. Complete response of brain metastasis was recognized in CT scan and gait disturbance was complete recovered two months after the treatment. She is now living well.
authors.affiliation: Dept. of Surgery, Hoshi General Hospital.
authors.forename: T
authors.initials: T
authors.lastname: Nomizu
authors.forename: F
authors.initials: F
authors.lastname: Watanabe
authors.forename: K
authors.initials: K
authors.lastname: Honda
authors.forename: M
authors.initials: M
authors.lastname: Kanazawa
authors.forename: Y
authors.initials: Y
authors.lastname: Yamaki
authors.forename: A
authors.initials: A
authors.lastname: Tsuchiya
authors.forename: R
authors.initials: R
authors.lastname: Abe
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000188:drug therapy / Q000556:secondary*; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D015409:Mastectomy, Radical; D012074:Remission Induction; D013629:Tamoxifen / Q000627:therapeutic use*; D005641:Tegafur / Q000008:administration & dosage; D014498:Uracil / Q000008:administration & dosage
chemical_list: D013629:Tamoxifen; D005641:Tegafur; D014498:Uracil