Primary laryngeal malignant fibrous histiocytoma: a case report.
Malignant fibrous histiocytoma (MFH) of the upper respiratory tract is rare. We report a case of laryngeal MFH in a 78-year-old man. The patient died 8 months after the first surgical treatment. The clinicopathologic features are described, and the importance of electron microscopy and immunohistochemical techniques in the differential diagnosis with so-called "sarcomatoid carcinoma" is stressed. The tumor has an aggressive biological behavior and tends to recur and metastasize.
De Rosa
G
G
Istituto di Pathologia, II Facoltà di Medicina e Chirurgia, Università di Napoli, Italy.
Palombini
L
L
Terracciano
L M
LM
D'Angelo
L
L
D000368:Aged; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology*; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D009367:Neoplasm Staging