SH abundant body in infantile digital fibromatosis--a histochemical study on distribution of sulfhydryl groups.
A case of infantile digital fibromatosis was studied with regard to the distribution of -SH groups and SS linkages, using N-(7-dimethylamino-4-methyl-3-coumarinyl) maleimide (DACM) stain. Tumor cells showed a strong fluorescence in the cytoplasm from the -SH stain. A brilliant -SH fluorescence was also homogenously present on the intracytoplasmic inclusions. SS reactivity was negative. Although further studies should be necessary to ascertain this finding, the DACM stain may make a simple and objective diagnostic method of infantile digital fibromatosis.
Kanamori
M
M
Department of Dermatology, Mie University School of Medicine, Japan.
Hashimoto
K
K
Tanaka
H
H
Shimizu
M
M
D005033:Ethylmaleimide; D005350:Fibroma / Q000737:chemistry*; D005534:Foot Diseases / Q000378:metabolism*; D006801:Humans; D002479:Inclusion Bodies / Q000737:chemistry; D007202:Indicators and Reagents; D007223:Infant; D008297:Male; D008301:Maleimides; D012878:Skin Neoplasms / Q000737:chemistry*; D013438:Sulfhydryl Compounds / Q000032:analysis*; D013439:Sulfhydryl Reagents; D013455:Sulfur / Q000032:analysis*; D014034:Toes
D007202:Indicators and Reagents; D008301:Maleimides; D013438:Sulfhydryl Compounds; D013439:Sulfhydryl Reagents; C019347:N-(7-dimethylamino-4-methylcoumarinyl)maleimide; D013455:Sulfur; D005033:Ethylmaleimide