Environmental stimuli and transcriptional activity generate transient changes in DNA torsional tension.
Transient changes in DNA torsional tension are generated by environmental stimuli and transcriptional activity. In eukaryotic cells, these changes can only be accommodated by a chromatin structure that is flexible. This property of chromatin may be essential to the regulation of eukaryotic gene activity.
Saavedra
R A
RA
Laboratory for the Study of Skeletal Disorders, Children's Hospital, Boston, MA 02115.
D002843:Chromatin / Q000502:physiology* / Q000648:ultrastructure; D004247:DNA / Q000235:genetics* / Q000648:ultrastructure; D005786:Gene Expression Regulation; D009690:Nucleic Acid Conformation; D014158:Transcription, Genetic
D002843:Chromatin; D004247:DNA