Environmental diseases of the digestive system.
Environmental factors are important mediators of many diseases of the digestive system, defined as the alimentary tract and the accessory organs of digestion, the liver and pancreas. In this review, we principally focus on the action of chemical agents which are classified as (1) naturally occurring compounds, (2) occupational hazards, (3) therapeutic drugs, and (4) constituents of substances of abuse. In addition, the putative role of dietary habits in the pathogenesis of malignant diseases of the digestive system is discussed.
Rubin
E
E
Department of Pathology and Cell Biology, Jefferson Medical College, Philadelphia, Pennsylvania.
Farber
J L
JL
D000428:Alcohol Drinking; D056486:Chemical and Drug Induced Liver Injury; D004032:Diet / Q000009:adverse effects; D004066:Digestive System Diseases / Q000139:chemically induced* / Q000209:etiology; D004067:Digestive System Neoplasms / Q000139:chemically induced / Q000209:etiology; D004781:Environmental Exposure; D004935:Esophageal Diseases / Q000139:chemically induced / Q000209:etiology; D005767:Gastrointestinal Diseases / Q000139:chemically induced / Q000209:etiology; D006801:Humans; D008107:Liver Diseases / Q000209:etiology; D009059:Mouth Diseases / Q000139:chemically induced / Q000209:etiology; D012907:Smoking / Q000009:adverse effects