title: Suppression of lymphocyte blastogenesis to mitogens in cats experimentally infected with feline immunodeficiency virus.
abstract: Lymphocytes from normal cats or cats experimentally infected with feline immunodeficiency virus (FIV) were stimulated with phytohemagglutinin, pokeweed mitogen, or concanavalin A. Lymphocytes from infected cats had lower responses than those from uninfected cats. These results support the hypothesis that FIV induces immunosuppression.
authors.affiliation: Department of Microbiology, Immunology, and Parasitology, New York State College of Veterinary Medicine, Cornell University, Ithaca 14853-6401.
authors.forename: D S
authors.initials: DS
authors.lastname: Lin
authors.forename: D D
authors.initials: DD
authors.lastname: Bowman
authors.forename: R H
authors.initials: RH
authors.lastname: Jacobson
authors.forename: M C
authors.initials: MC
authors.lastname: Barr
authors.forename: M
authors.initials: M
authors.lastname: Fevereiro
authors.forename: J R
authors.initials: JR
authors.lastname: Williams
authors.forename: F M
authors.initials: FM
authors.lastname: Noronha
authors.forename: F W
authors.initials: FW
authors.lastname: Scott
authors.forename: R J
authors.initials: RJ
authors.lastname: Avery
mesh_terms: D000818:Animals; D002415:Cats; D002478:Cells, Cultured; D003208:Concanavalin A; D004797:Enzyme-Linked Immunosorbent Assay; D016181:Feline Acquired Immunodeficiency Syndrome / Q000276:immunology*; D005260:Female; D007108:Immune Tolerance; D016089:Immunodeficiency Virus, Feline / Q000276:immunology*; D008213:Lymphocyte Activation / Q000276:immunology; D008297:Male; D010835:Phytohemagglutinins; D011043:Pokeweed Mitogens; D013047:Specific Pathogen-Free Organisms; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D010835:Phytohemagglutinins; D011043:Pokeweed Mitogens; D003208:Concanavalin A