[Current theories on the mechanism of the effect of glucagon on carbohydrate metabolism].
Glucagon is considered for mechanisms of its action on the carbon metabolism, its significance in the complex polyhormonal regulation of the glucose synthesis and metabolism being studied. Glucagon exerts its effect on cells through specific receptors arranged on the plasma membrane, while its effect on the carbohydrate metabolism is mediated, mainly, by cAMP-dependent phosphorylation os some proteins participating in regulation of carbohydrate synthesis and metabolism including the proteins controlling expression of many genes. The glucagon effect on the level and efficiency of the action of insulin and some other hormones is an important link in the glucagon action on the carbohydrate metabolism.
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D050260:Carbohydrate Metabolism; D000242:Cyclic AMP / Q000502:physiology; D005934:Glucagon / Q000502:physiology*; D005943:Gluconeogenesis / Q000502:physiology*; D005947:Glucose / Q000378:metabolism; D006019:Glycolysis / Q000502:physiology*; D006801:Humans; D007328:Insulin / Q000502:physiology; D008930:Mitochondria, Liver / Q000378:metabolism; D010085:Oxidative Phosphorylation; D011956:Receptors, Cell Surface / Q000378:metabolism
D007328:Insulin; D011956:Receptors, Cell Surface; D005934:Glucagon; D000242:Cyclic AMP; D005947:Glucose
Sovremennye predstavleniia o mekhanizme deĭstviia gliukagona na uglevodnyĭ obmen.