title: A new genome type of adenovirus 3 associated with severe lower acute respiratory infection in children.
abstract: Adenovirus 3 was found associated with ten cases of infantile lower acute respiratory infection in patients aged 2-18 months. Of these, five had a fatal outcome, with severe lung damage. Restriction enzyme analysis with Bam HI, Bcl I, Bgl II, Bst E II, Hind III, Sal I, Sma I, Xba I, and Xho I revealed the presence of the same genome type in all ten specimens. The genomic variant was different from those previously reported for serotype 3 and therefore was tentatively denominated 3f.
authors.affiliation: BioSidus S.A., Buenos Aires, Argentina.
authors.forename: A E
authors.initials: AE
authors.lastname: Kajon
authors.forename: P
authors.initials: P
authors.lastname: Murtagh
authors.forename: S
authors.initials: S
authors.lastname: Garcia Franco
authors.forename: M C
authors.initials: MC
authors.lastname: Freire
authors.forename: M C
authors.initials: MC
authors.lastname: Weissenbacher
authors.forename: J
authors.initials: J
authors.lastname: Zorzópulos
mesh_terms: D000208:Acute Disease; D000257:Adenoviridae Infections / Q000209:etiology*; D000258:Adenovirus Infections, Human / Q000209:etiology*; D000260:Adenoviruses, Human / Q000235:genetics; D002478:Cells, Cultured; D004279:DNA, Viral / Q000235:genetics; D005260:Female; D006801:Humans; D007223:Infant; D008171:Lung Diseases / Q000209:etiology*; D008297:Male; D015183:Restriction Mapping
chemical_list: D004279:DNA, Viral