title: False aneurysm infected by Aspergillus fumigatus: an unusual complication of aortofemoral bypass graft.
abstract: Two cases of Aspergillus fumigatus infection of aortobifemoral prosthetic grafts are reported. Both patients were treated successfully by excision of the infected prosthetic material, axillofemoral extra-anatomic bypass, and prolonged medical treatment. The patients received amphotericin B, 5-flucytosine and itraconazole until negative aspergillus serology was obtained (at 9 and 18 months, respectively). Later, repeat disobliteration procedures for thrombosis of the axillofemoral bypass were required. No recurrent aspergillus infection was found.
authors.affiliation: Service de Chirurgie Thoracique et Vasculaire, Hôpital Beaujon, Clichy, France.
authors.forename: O
authors.initials: O
authors.lastname: Nussaume
authors.forename: M
authors.initials: M
authors.lastname: Elzaabi
authors.forename: P
authors.initials: P
authors.lastname: Icard
authors.forename: C
authors.initials: C
authors.lastname: Branger
authors.forename: S
authors.initials: S
authors.lastname: Bouttier
authors.forename: B
authors.initials: B
authors.lastname: Andreassian
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000785:Aneurysm, Infected / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D000935:Antifungal Agents / Q000627:therapeutic use; D001012:Aorta, Abdominal / Q000601:surgery*; D001228:Aspergillosis / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D001232:Aspergillus fumigatus; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D005263:Femoral Artery / Q000601:surgery*; D005437:Flucytosine / Q000627:therapeutic use; D006801:Humans; D017964:Itraconazole; D007654:Ketoconazole / Q000031:analogs & derivatives / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B; D005437:Flucytosine; D007654:Ketoconazole