title: Graft failure after penetrating keratoplasty.
abstract: Despite the improving results that have been noted with penetrating keratoplasty, graft failure remains a significant problem. The causes of graft failure are quite varied. Primary donor failure, surgical complications, intraocular lens complications, persistent epithelial defects, allograft rejection, infection, glaucoma, trauma, and recurrences of primary corneal dystrophies are common etiologies. In this article, a critical review of the available literature concerned with the factors influencing the many causes of graft failure and their management is provided.
authors.affiliation: Louisiana State University Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans.
authors.forename: S E
authors.initials: SE
authors.lastname: Wilson
authors.forename: H E
authors.initials: HE
authors.lastname: Kaufman
mesh_terms: D004848:Epithelium / Q000473:pathology; D005128:Eye Diseases / Q000150:complications; D005131:Eye Injuries / Q000150:complications; D006084:Graft Rejection / Q000276:immunology; D006801:Humans; D015948:Keratoplasty, Penetrating / Q000009:adverse effects* / Q000379:methods; D007910:Lenses, Intraocular / Q000009:adverse effects; D012307:Risk Factors; D014019:Tissue Donors