Immunoblot analysis of the humoral immune response to cytomegalovirus in non-pregnant and pregnant guinea pigs.
The temporal appearance of antibodies to guinea pig cytomegalovirus (CMV) proteins was examined in pregnant and non-pregnant guinea pigs by immunoblotting. Antibodies to 12 guinea pig CMV proteins appeared in a defined time course during primary infection and were detected at a later time and in lower concentrations in pregnant than in non-pregnant guinea pigs.
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Department of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut.
Griffith
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D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis* / Q000276:immunology; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000276:immunology*; D005260:Female; D006168:Guinea Pigs; D015151:Immunoblotting; D007700:Kinetics; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology*; D015678:Viral Structural Proteins / Q000276:immunology*
D000914:Antibodies, Viral; D015678:Viral Structural Proteins