[The incidence of influenzal, para-influenzal and adenoviral antigens in keratoconjunctivitis patients during immunization with NIVGRIP vaccine].
Repeated intranasal administrations of NIVGRIP, influenza inactivated vaccine, to patients with chronic recurrent keratoconjunctivitis, led to a significant reduction of respiratory virus incidence, as revealed by the immunofluorescence test in the conjunctive epithelial cells. The effect is probably due to endogenous interferon stimulation by the vaccine, at the nasopharyngeal level.
Athanasiu
P
P
Institut de Virologie Stefan S. Nicolau, Bucarest, Roumanie.
Petrescu
A
A
Predescu
E
E
Anghelescu
S
S
Popa
D P
DP
Dumitrescu
A M
AM
Macarie
I
I
Cristea
C
C
Mihail
V
V
D000260:Adenoviruses, Human / Q000276:immunology*; D000281:Administration, Intranasal; D000956:Antigens, Viral / Q000032:analysis*; D002908:Chronic Disease; D004306:Dose-Response Relationship, Immunologic; D005455:Fluorescent Antibody Technique; D006801:Humans; D007114:Immunization; D009980:Influenza A virus / Q000276:immunology*; D009981:Influenza B virus / Q000276:immunology*; D007252:Influenza Vaccines / Q000008:administration & dosage / Q000276:immunology*; D007637:Keratoconjunctivitis / Q000276:immunology*; D012008:Recurrence; D018108:Respirovirus / Q000276:immunology*; D015164:Vaccines, Inactivated / Q000008:administration & dosage / Q000276:immunology
D000956:Antigens, Viral; D007252:Influenza Vaccines; D015164:Vaccines, Inactivated
Incidence des antigènes grippal, paragrippal et adénoviral chez des sujets à kérato-conjonctivite durant l'immunisation avec du vaccin NIVGRIP.