[Eosinophilic myocarditis and pulmonary hypertension in a drug-addict. Anatomo-clinical study and brief review of the literature].
We report the clinical and pathological findings in a young female patient who was a chronic drug addict for over eight years. In 1984, she presented with tricuspid endocarditis and three years later, was found to have irreversible pulmonary hypertension. Post-mortem examination revealed not only persistent tricuspid endocarditis and evidence of repeated pulmonary thromboembolism explaining her pulmonary hypertension but also a diffuse eosinophilic myocarditis, with myocardial fibre degeneration. The combined pulmonary and myocardial lesions have rarely been documented in the same drug addict. The relationship of these various pathological findings are discussed in the light of the existing literature.
Talebzadeh
V C
VC
Départements de Pathologie, Université de Genève, Suisse.
Chevrolet
J C
JC
Chatelain
P
P
Helfer
C
C
Cox
J N
JN
D000328:Adult; D003042:Cocaine; D004802:Eosinophilia / Q000150:complications / Q000209:etiology / Q000473:pathology*; D005260:Female; D006556:Heroin Dependence / Q000150:complications*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications / Q000209:etiology / Q000473:pathology*; D009205:Myocarditis / Q000150:complications / Q000209:etiology / Q000473:pathology*; D011655:Pulmonary Embolism / Q000150:complications / Q000209:etiology / Q000473:pathology*; D019966:Substance-Related Disorders / Q000150:complications*
D003042:Cocaine
Myocardite à éosinophiles et hypertension pulmonaire chez une toxicomane. Etude anatomo-clinique et brève revue de la littérature.