Globular cytoplasmic inclusion bodies in a metastatic hepatocellular carcinoma of the iliac bone.
Globular filamentous bodies are one of the well-known inclusion bodies in hepatocellular carcinoma. The article describes a 56-year-old man with an occult hepatocellular carcinoma in whom the first histologic diagnosis was made from a biopsy from bone. Ultrastructural examination showed many globular filamentous bodies similar to Mallory bodies. The ultrastructural findings and the diagnostic value of these filamentous bodies are discussed.
Haratake
J
J
Department of Pathology and Oncology, University of Occupational and Environmental Health School of Medicine, Kitakyushu, Japan.
Horie
A
A
Setojima
M
M
D001859:Bone Neoplasms / Q000556:secondary* / Q000648:ultrastructure; D006528:Carcinoma, Hepatocellular / Q000648:ultrastructure*; D002467:Cell Nucleus / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D006651:Histocytochemistry; D006801:Humans; D007085:Ilium; D007150:Immunohistochemistry; D002479:Inclusion Bodies / Q000648:ultrastructure*; D008113:Liver Neoplasms / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged