title: [The interrelationship of cytomegalovirus infection and immunodeficiencies].
abstract: The results of examination of 87 children who died from a generalized cytomegalovirus infection in Elista (66 cases) in 1984-1985, 1988-89, and in Leningrad (21 cases) in 1988-89 are available. In the Elista material a considerable increase (from 21 to 66%) of severe forms of accidental transformation of thymus is observed in the second period comparing to the first one. The causes of a serious worsening of the immunological background remain unclear. Cytomegaly represented 3.85% of all dead children in the pathology department of the First Children Hospital of Leningrad. There was sialadenitis in 4 cases and generalized infection with involvement of the lungs, liver, kidneys, brain, myocardium, pancreas, adrenals in 17 cases. Cytomegaly was diagnosed in 3 of 5 cases of primary immunodeficiency. Diagnosis in some cases was confirmed by the DNA cytomegalovirus detection by means of PCR reaction.
authors.forename: V A
authors.initials: VA
authors.lastname: Tsinzerling
authors.forename: G G
authors.initials: GG
authors.lastname: Vasil'eva
authors.forename: M G
authors.initials: MG
authors.lastname: Indikova
authors.forename: S D
authors.initials: SD
authors.lastname: Popov
mesh_terms: D002648:Child; D002675:Child, Preschool; D003586:Cytomegalovirus Infections / Q000175:diagnosis / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000175:diagnosis / Q000473:pathology*; D007223:Infant; D008297:Male; D012426:Russia; D012698:Serologic Tests; D013950:Thymus Gland / Q000473:pathology; D014505:Urban Population
vernacular_title: O vzaimootnoshenii tsitomegalovirusnoĭ infektsii i immunodefitsitov.