title: Recombinant hirudin displaces human factor Xa from its endothelial binding sites.
authors.affiliation: Department of Pathology, Duke University Medical Center, Durham, NC 27710.
authors.forename: S V
authors.initials: SV
authors.lastname: Pizzo
authors.forename: R C
authors.initials: RC
authors.lastname: Friedberg
authors.forename: P
authors.initials: P
authors.lastname: Sze
authors.forename: R
authors.initials: R
authors.lastname: Winant
authors.forename: D
authors.initials: D
authors.lastname: Hudson
authors.forename: J M
authors.initials: JM
authors.lastname: Lazar
authors.forename: P H
authors.initials: PH
authors.lastname: Johnson
mesh_terms: D000818:Animals; D001667:Binding, Competitive; D002417:Cattle; D002478:Cells, Cultured; D004730:Endothelium, Vascular / Q000166:cytology / Q000378:metabolism; D015951:Factor Xa / Q000378:metabolism*; D006629:Hirudins / Q000378:metabolism / Q000494:pharmacology*; D006801:Humans; D010980:Platelet Membrane Glycoproteins; D011956:Receptors, Cell Surface / Q000187:drug effects* / Q000378:metabolism; D011994:Recombinant Proteins / Q000378:metabolism / Q000494:pharmacology
chemical_list: D006629:Hirudins; D010980:Platelet Membrane Glycoproteins; D011956:Receptors, Cell Surface; D011994:Recombinant Proteins; C045069:factor X receptors; D015951:Factor Xa