Nucleotide sequence of the 5'-terminal palindrome of Aleutian mink disease parvovirus and construction of an infectious molecular clone.
The 5'-terminal palindrome of the ADV-G strain of Aleutian mink disease parvovirus (ADV) was molecularly cloned and sequenced. A full-length molecular clone of ADV-G, denoted pXVB, was then constructed. When this clone was transfected into cell cultures, infectious ADV could be rescued. Virus derived from pXVB was nonpathogenic for adult mink, as is the parent ADV-G strain.
Bloom
M E
ME
Laboratory of Persistent Viral Disease, National Institute of Allergy and Infectious Diseases, Hamilton, Montana 59840.
Alexandersen
S
S
Garon
C F
CF
Mori
S
S
Wei
W
W
Perryman
S
S
Wolfinbarger
J B
JB
D000454:Aleutian Mink Disease Virus / Q000235:genetics* / Q000276:immunology; D000818:Animals; D000956:Antigens, Viral / Q000235:genetics; D001483:Base Sequence; D002415:Cats; D002460:Cell Line; D003001:Cloning, Molecular; D004279:DNA, Viral / Q000235:genetics; D005814:Genes, Viral; D008854:Microscopy, Electron; D008969:Molecular Sequence Data; D010321:Parvoviridae / Q000235:genetics*; D014162:Transfection; D015678:Viral Structural Proteins / Q000235:genetics; D014779:Virus Replication
D000956:Antigens, Viral; D004279:DNA, Viral; D015678:Viral Structural Proteins