title: [Prognosis and therapy of primary epithelial liver tumors. Evaluating a personal patient sample].
abstract: Prognostically relevant factors and treatment were analysed in 103 patients suffering from primary epithelial liver tumors (88 HCC, 15 CCC). Ninety of them underwent operations: 14 liver transplantations, 32 resections, 44 explorative laparotomies. The resection rate was 38%, the 30-day mortality in transplantation 14%, in resection 22%. The 5-year survival after resection was about 25%. Liver transplantation resulted in 50% 1-year and 40% 2-year survival. Long-term prognosis was positively influenced by cirrhosis and formation of a tumor capsule. Indications for operative management depend only on extension of tumor growth and concomiting liver cirrhosis as biology of epithelial liver tumors is poorly understood.
authors.affiliation: Chirurgische Universitätsklinik Heidelberg.
authors.forename: G
authors.initials: G
authors.lastname: Otto
authors.forename: U
authors.initials: U
authors.lastname: Heuschen
authors.forename: W
authors.initials: W
authors.lastname: Hofmann
authors.forename: P
authors.initials: P
authors.lastname: Schlag
authors.forename: C
authors.initials: C
authors.lastname: Herfarth
mesh_terms: D002759:Adenoma, Bile Duct / Q000473:pathology / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D000368:Aged; D001650:Bile Duct Neoplasms / Q000473:pathology / Q000601:surgery*; D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D008099:Liver / Q000473:pathology; D008103:Liver Cirrhosis / Q000473:pathology / Q000601:surgery*; D008113:Liver Neoplasms / Q000473:pathology / Q000601:surgery*; D016031:Liver Transplantation / Q000379:methods; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000401:mortality
vernacular_title: Zur Prognose und Therapie primärer epithelialer Lebertumoren. Evaluierung des eigenen Krankengutes.