title: [Bone marrow metastases of neuroblastoma: MRT in comparison with bone marrow cytology and mIBG scintigraphy].
abstract: Thirteen MRT investigations of the knee region of nine children with neuroblastoma stage IV/III were performed in order to demonstrate bone-marrow metastases. The MRT-findings were correlated with bone-marrow cytology, immunofluorescence, and mIBG-scintigraphy. MRT showed a high sensitivity in demonstrating bone-marrow abnormalities, although bone-marrow aspiration and mIBG-scintigraphy will still be needed to make a specific diagnosis. On the other hand, signs of bone-marrow involvement in MRT investigations without positive findings in bone-marrow cytology and mIBG-scintigraphy may be the first evidence of bone-marrow metastases.
authors.affiliation: Institut und Poliklinik für Radiologische Diagnostik, Universität zu Köln.
authors.forename: G
authors.initials: G
authors.lastname: Benz-Bohm
authors.forename: W
authors.initials: W
authors.lastname: Gross-Fengels
authors.forename: B
authors.initials: B
authors.lastname: Widemann
authors.forename: A
authors.initials: A
authors.lastname: Linden
mesh_terms: D019797:3-Iodobenzylguanidine; D000293:Adolescent; D001853:Bone Marrow / Q000473:pathology*; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D008279:Magnetic Resonance Imaging; D008297:Male; D009447:Neuroblastoma / Q000000981:diagnostic imaging / Q000473:pathology*; D011877:Radionuclide Imaging
chemical_list: D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D019797:3-Iodobenzylguanidine
vernacular_title: Knochenmarkmetastasierung bei Neuroblastom: MRT im Vergleich zur Knochenmarkzytologie und mIBG-Szintigraphie.