[Isolated ACTH deficiency: description of a clinical case].
A 34-year man was admitted to the hospital with symptoms of hypoglycemia. The endocrine investigations indicated adrenocortical insufficiency secondary to isolated ACTH deficiency: low ACTH and cortisol plasma levels, significant increase of cortisol following prolonged stimulation with depot tetracosactrin, normal secretory reserve of other anterior pituitary hormones. The absence of ACTH-response after corticotropin releasing hormone and insulin tolerance tests suggested a primary impairment of corticotropin cells.
Spagnolli
W
W
Divisione di Medicina I, Ospedale S. Chiara, Trento.
De Venuto
G
G
Mattarei
M
M
Ramponi
C
C
Dal Follo
M
M
Miori
R
R
D000324:Adrenocorticotropic Hormone / Q000172:deficiency*; D000328:Adult; D003346:Corticotropin-Releasing Hormone; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007003:Hypoglycemia / Q000175:diagnosis; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D011388:Prolactin / Q000097:blood; D013972:Thyrotropin / Q000097:blood
D000324:Adrenocorticotropic Hormone; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin; D003346:Corticotropin-Releasing Hormone; D011241:Prednisone
Deficit isolato di ACTH: descrizione di un caso clinico.