Facilitative glucose transporters: an expanding family.
The uptake of glucose into most eukaryotic cells is accomplished by a carrier-mediated transport system, facilitative diffusion, which transports glucose down its chemical gradient in a stereospecific manner. Recent studies have shown that facilitative transport of glucose across the plasma membrane is mediated by a family of structurally related proteins. This review summarizes the structural and functional features of the family of facilitative glucose transporters.
Gould
G W
GW
Department of Biochemistry, University of Glasgow, UK.
Bell
G I
GI
D000595:Amino Acid Sequence; D003920:Diabetes Mellitus / Q000378:metabolism; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D008969:Molecular Sequence Data; D009004:Monosaccharide Transport Proteins / Q000378:metabolism*; D011487:Protein Conformation
D009004:Monosaccharide Transport Proteins; D005947:Glucose