[Cancer cells in the portal and hepatic veins of resected specimens of hepatocellular carcinomas].
After injecting 100 ml of a saline solution into the hepatic artery of 27 livers evidencing a hepatocellular carcinoma, samples from the resected livers were collected through the portal and the hepatic vein. Cancer cells were detected in 4 out of 27 samples from the portal vein and in 1 out of 19 samples from the hepatic vein, and the total number of positive cases were 4. Further, tumors over 5 cm in diameter showed a tendency of flowing cancer cells into the portal vein. Four positive cases had an intrahepatic and a distant metastasis within one year of their operation and two of these patients died.
Yamamoto
M
M
Institute of Gastroenterology, Tokyo Women's Med. College.
Takasaki
K
K
Yagawa
A
A
Tsugita
T
T
Nakagawa
M
M
Aruga
A
A
Hayashi
T
T
Shimizu
T
T
Miyazaki
S
S
Suzuki
T
T
D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000098:blood supply / Q000473:pathology*; D005260:Female; D006503:Hepatic Veins / Q000473:pathology*; D006801:Humans; D008113:Liver Neoplasms / Q000098:blood supply / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009360:Neoplastic Cells, Circulating / Q000473:pathology*; D011169:Portal Vein / Q000473:pathology*