Inflammation-mediated chondrocyte unresponsiveness to insulin-like growth factor-1 is not caused by H2O2.
Joosten
L A
LA
Department of Rheumatology, University of Nijmegen, The Netherlands.
Helsen
M M
MM
van den Berg
W B
WB
D000818:Animals; D002356:Cartilage / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D005260:Female; D006861:Hydrogen Peroxide / Q000494:pharmacology*; D007249:Inflammation / Q000378:metabolism / Q000503:physiopathology*; D007334:Insulin-Like Growth Factor I / Q000378:metabolism / Q000502:physiology*; D007457:Iodine Radioisotopes; D051379:Mice; D008810:Mice, Inbred C57BL; D011956:Receptors, Cell Surface / Q000378:metabolism; D017451:Receptors, Somatomedin; D013002:Somatomedins / Q000502:physiology*
D007457:Iodine Radioisotopes; D011956:Receptors, Cell Surface; D017451:Receptors, Somatomedin; D013002:Somatomedins; D007334:Insulin-Like Growth Factor I; D006861:Hydrogen Peroxide