title: [Hereditary site-specific colon cancer--report of two families].
abstract: Five cases of hereditary site-specific colon cancer (HSSCC or Lynch syndrome I) from two families are reported. The main features of HSSCC are: an autosomal dominant model of heredity, the absence of associated polyposis, the average age being younger, vulnerable site being the right colon (4/5 cases), multiple colon cancers (3/5 cases) and long survival. These 5 cases possessed the above mentioned features. Having no special detection method, the authors suggest that the members of these families be registered and the high risk members regularly checked.
authors.affiliation: Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Beijing.
authors.forename: Y F
authors.initials: YF
authors.lastname: Shao
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics* / Q000601:surgery; D002288:Adenocarcinoma, Mucinous / Q000235:genetics / Q000601:surgery; D000231:Adenocarcinoma, Papillary / Q000235:genetics / Q000601:surgery; D000328:Adult; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis / Q000235:genetics* / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged