Investigation of the mechanism by which sigma ligands inhibit stimulation of phosphoinositide metabolism by muscarinic cholinergic agonists.
Bowen
W D
WD
Division of Biology and Medicine, Brown University, Providence, Rhode Island 02912.
Tolentino
P
P
Varghese
P
P
D000818:Animals; D001921:Brain / Q000378:metabolism; D066298:In Vitro Techniques; D008297:Male; D010277:Parasympathomimetics / Q000494:pharmacology*; D010716:Phosphatidylinositols / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D011957:Receptors, Opioid / Q000187:drug effects / Q000378:metabolism*; D017480:Receptors, sigma; D013574:Synaptosomes / Q000378:metabolism
D010277:Parasympathomimetics; D010716:Phosphatidylinositols; D011957:Receptors, Opioid; D017480:Receptors, sigma