Free radicals and SOD activity of jaw cyst. Direct measurement and spin trapping studies by ESR.
Free radicals produced in the fluid of jaw cysts were directly measured at room temperature using ESR. With these samples, SOD activity of the cyst fluid was measured by the ESR spin trapping method with DMPO as a trapping agent. Freeze-dried samples of cyst fluid showed a broad ESR signal at g = 2.005. Relative signal intensity of samples from jaw cysts with inflammation was higher than jaw cysts without inflammation. SOD activity of cyst fluid with high viscosity showed higher values than that of cyst fluid with low viscosity. We suggest that free radicals produced in jaw cyst damage tissues while higher SOD activity of cyst fluid play a role in a self-defense mechanism against free radicals.
Kimura
H
H
Department of Dentistry and Oral Surgery, Hirosaki University School of Medicine, Japan.
Simodate
H
H
Suzuki
M
M
D001826:Body Fluids / Q000378:metabolism; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals; D006801:Humans; D007570:Jaw Cysts / Q000201:enzymology / Q000378:metabolism*; D013113:Spin Labels; D013482:Superoxide Dismutase / Q000378:metabolism*
D005609:Free Radicals; D013113:Spin Labels; D013482:Superoxide Dismutase