title: Sleep is undisturbed in elderly, depressed individuals who have not sought health care.
abstract: Sleep deficits are commonly found in geriatric depressed patients, particularly shortened rapid eye movements (REM) latency, disturbed sleep continuity, and decreased slow wave sleep (SWS). Here we report the sleep patterns of community volunteers responding to ads about memory loss and depression. The two groups, 24 geriatric-onset major depressive disorder (MDD) subjects with a minimal history of seeking treatment for depression and 24 gender- and age-matched control subjects, significantly differed from each other on only one measure of sleep--sleep latency; the MDD group showed a modest but significant shortening of latency to fall asleep. All other sleep/wake measures, including REM latency, temporal distribution of REM sleep across the night, SWS, and measures of nighttime wakefulness did not differ between groups. This lack of significant sleep disturbance suggests that the sleep deficits reported in many studies of major depression may be related to factors underlying treatment-seeking behaviors, physical health status, severity of the depression, or heterogeneity within the MDD population with some types seeking treatment and others not seeking it, rather than depressive state per se. The data indicate that community-dwelling healthy elderly individuals who have a diagnosed major depression but who have not actively sought health care do not necessarily manifest the sleep disturbances thought to be characteristic of major depressive illness.
authors.affiliation: Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle 98195.
authors.forename: M V
authors.initials: MV
authors.lastname: Vitiello
authors.forename: P N
authors.initials: PN
authors.lastname: Prinz
authors.forename: D H
authors.initials: DH
authors.lastname: Avery
authors.forename: D E
authors.initials: DE
authors.lastname: Williams
authors.forename: R K
authors.initials: RK
authors.lastname: Ries
authors.forename: J A
authors.initials: JA
authors.lastname: Bokan
authors.forename: A
authors.initials: A
authors.lastname: Khan
mesh_terms: D002986:Clinical Trials as Topic; D003866:Depressive Disorder / Q000503:physiopathology / Q000523:psychology*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic; D010342:Patient Acceptance of Health Care; D012893:Sleep Wake Disorders / Q000523:psychology*; D012895:Sleep, REM