Parvovirus B19-associated hemophagocytic syndrome.
Parvovirus B19 is a recently described pathogen, associated with an increasing spectrum of clinical manifestations. We present the first reported case, to our knowledge, of parvovirus B19-associated hemophagocytic syndrome, in which the diagnosis of parvovirus infection was documented by the presence of B19-specific IgM and IgG antibodies. Pancytopenia resolved immediately following splenectomy and the patient recovered completely.
Boruchoff
S E
SE
Department of Medicine, University of Massachusetts Medical Center, Worcester 01655.
Woda
B A
BA
Pihan
G A
GA
Durbin
W A
WA
Burstein
D
D
Blacklow
N R
NR
D000914:Antibodies, Viral / Q000032:analysis; D002648:Child; D015616:Histiocytosis, Non-Langerhans-Cell / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008297:Male; D010321:Parvoviridae / Q000302:isolation & purification; D010322:Parvoviridae Infections / Q000175:diagnosis* / Q000473:pathology; D013154:Spleen / Q000473:pathology
D000914:Antibodies, Viral