title: [Malignant fibrous histiocytoma of soft tissue: atypical presentations. Value of combined surgery and chemotherapy].
abstract: The authors report five cases of malignant fibrous histiocytoma of the soft tissues, some of them with atypical presentation (necrotizing tumor, hypereosinophilic syndrome, dermatomyositis). This is the first case of polymyositis associated with malignant fibrous histiocytoma. The tumor occurs between the fifth and the seventh decade, principally as a mass on the proximal lower limb. Local recurrence and metastasis occurs in 50% of patients. Prognosis is dependent on both the surgical possibilities and the characteristics of the tumor (site, size, histologic grade). Surgery alone is inadequate. Adjuvant chemotherapy improves the 5-year survival.
authors.affiliation: Service de Médecine Interne du Pr GODEAU, Hôpital de la Pitié, Paris.
authors.forename: P
authors.initials: P
authors.lastname: Cherin
authors.forename: J C
authors.initials: JC
authors.lastname: Piette
authors.forename: O
authors.initials: O
authors.lastname: Bletry
authors.forename: Y
authors.initials: Y
authors.lastname: Le Charpentier
authors.forename: T
authors.initials: T
authors.lastname: Judet
authors.forename: F
authors.initials: F
authors.lastname: Richard
authors.forename: M
authors.initials: M
authors.lastname: Gatfosse
authors.forename: L
authors.initials: L
authors.lastname: Aubert
authors.forename: M
authors.initials: M
authors.lastname: Mornet
authors.forename: B
authors.initials: B
authors.lastname: Wechsler
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012186:Retroperitoneal Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D013997:Time Factors
vernacular_title: Histioctome fibreux malin des tissus mous: présentations atypiques. Intérêt de l'association chirurgie-chimiothérapie.