title: Arcaine is a competitive antagonist of the polyamine site on the NMDA receptor.
authors.affiliation: Department of Pharmacology, University of Pittsburgh, PA 15261.
authors.forename: I J
authors.initials: IJ
authors.lastname: Reynolds
mesh_terms: D001645:Biguanides / Q000378:metabolism*; D001667:Binding, Competitive / Q000187:drug effects; D015317:Biogenic Polyamines / Q000378:metabolism*; D003986:Dibenzocycloheptenes / Q000378:metabolism*; D016291:Dizocilpine Maleate; D016194:Receptors, N-Methyl-D-Aspartate; D017981:Receptors, Neurotransmitter / Q000378:metabolism*; D013095:Spermidine / Q000494:pharmacology
chemical_list: D001645:Biguanides; D015317:Biogenic Polyamines; D003986:Dibenzocycloheptenes; D016194:Receptors, N-Methyl-D-Aspartate; D017981:Receptors, Neurotransmitter; C006624:arcaine; D016291:Dizocilpine Maleate; D013095:Spermidine