title: [The morphologic reaction pattern to fiber dust].
abstract: In principle, the fibrosing, preneoplastic and neoplastic morphological reactions to natural and man-made mineral fibres are relatively uniform, and are thus non-specific for the various different types of fibre. In order to establish a causal chain between the injurious "fibrous" agent and the morphologically and clinically manifest pathological lesion, close cooperation between epidemiologists, occupational physicians, pneumologists and pathologists is needed. On its own, the morphological contribution towards solving the problem is of only a limited nature. Light-microscopic, electron-microscopic and element-analytical studies, however, used in conjunction with the results obtained in animal experiments, in the individual case with consideration also being given to aspects of medical insurance, can lead to useful information for the clinical situation and for the generation of expertize.
authors.affiliation: Institut für Pathologie, Universitätsklinik Bochum.
authors.forename: K M
authors.initials: KM
authors.lastname: Müller
authors.forename: O A
authors.initials: OA
authors.lastname: Brinkmann
authors.forename: M
authors.initials: M
authors.lastname: Fischer
mesh_terms: D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D000818:Animals; D001194:Asbestos / Q000009:adverse effects*; D001195:Asbestosis / Q000473:pathology*; D017610:Calcium Compounds; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D004391:Dust / Q000009:adverse effects*; D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology*; D008855:Microscopy, Electron, Scanning; D011009:Pneumoconiosis / Q000473:pathology*; D017640:Silicates; D012824:Silicic Acid / Q000009:adverse effects*; D012822:Silicon Dioxide / Q000009:adverse effects*
chemical_list: D000395:Air Pollutants, Occupational; D017610:Calcium Compounds; D004391:Dust; D017640:Silicates; D001194:Asbestos; D012824:Silicic Acid; D012822:Silicon Dioxide; C031293:calcium silicate
vernacular_title: Morphologische Reaktionsmuster auf faserförmige Stäube.