title: Association of non-Hodgkin's lymphoma and hepatocellular carcinoma.
abstract: Four patients with hepatocellular carcinoma (HCC) out of a group of 132 with non-Hodgkin's lymphoma (NHL) are described. HCC was the most common second neoplasm in this series; in contrast, only 2 cases of HCC associated with NHL have been reported in the English literature. The diagnosis of HCC was suggested by ultrasound (US) and confirmed by ultrasonically guided fine-needle biopsy (UG-FNB). The 4 cases of HCC arose from cirrhosis. In this series, 10 out of 132 patients (7.6%) presented cirrhosis. Some considerations concerning the possible role of NHL (and/or the related therapy) in promoting the development of HCC in cirrhotic patients are discussed. The usefulness of US and of UG-FNB in the management of the patient with NHL is emphasized.
authors.affiliation: I Divisione Medica, Ospedale Civile, Piacenza, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Di Stasi
authors.forename: L
authors.initials: L
authors.lastname: Cavanna
authors.forename: F
authors.initials: F
authors.lastname: Fornari
authors.forename: G
authors.initials: G
authors.lastname: Civardi
authors.forename: S
authors.initials: S
authors.lastname: Rossi
authors.forename: G
authors.initials: G
authors.lastname: Sbolli
authors.forename: M
authors.initials: M
authors.lastname: Giacani
authors.forename: S
authors.initials: S
authors.lastname: Fermi
authors.forename: L
authors.initials: L
authors.lastname: Buscarini
mesh_terms: D000293:Adolescent; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D006528:Carcinoma, Hepatocellular / Q000209:etiology*; D005260:Female; D006509:Hepatitis B / Q000150:complications; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications; D008113:Liver Neoplasms / Q000209:etiology*; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D014463:Ultrasonography