title: Silica granuloma mimicking granulomatous cheilitis.
abstract: A 45-year-old female presented with macrocheilitis of the upper lip. Histologically numerous well-demarcated granulomas were present in the dermis and hypodermis. Examination under polarized light revealed birefringent crystalline particles. The patient had suffered a road accident 25 years ago. This case illustrates the characteristic features of silica granuloma without systemic manifestations. The clinical presentation as macrocheilitis may mislead into the wrong diagnosis.
authors.affiliation: Department of Dermatology, University Hospital, Geneva, Switzerland.
authors.forename: M
authors.initials: M
authors.lastname: Harms
authors.forename: I
authors.initials: I
authors.lastname: Masouyé
authors.forename: J H
authors.initials: JH
authors.lastname: Saurat
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006099:Granuloma / Q000175:diagnosis*; D006801:Humans; D008047:Lip Diseases / Q000175:diagnosis* / Q000473:pathology; D008556:Melkersson-Rosenthal Syndrome / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged; D012822:Silicon Dioxide / Q000009:adverse effects
chemical_list: D012822:Silicon Dioxide