Antibodies against hepatitis C in a population of Swedish haemophiliacs and heterosexual partners.
The prevalence of antibodies against hepatitis C virus in 160 Swedish patients with haemophilia or related coagulation disorders and 13 heterosexual partners was assessed by means of an ELISA method. A high prevalence of HCV antibodies was found in haemophiliacs with chronic hepatitis (87%), with HIV-antibodies (87%), with severe form of the coagulopathy (81%), and among those who at any point had received factor concentrates without viral inactivation (79%) or of foreign origin (84%). On the other hand, none of the partners were seropositive, indicating a low risk of sexual transmission.
Schulman
S
S
Department of Internal Medicine, Karolinska Hospital, Stockholm, Sweden.
Grillner
L
L
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006467:Hemophilia A / Q000097:blood*; D016174:Hepacivirus / Q000276:immunology*; D006526:Hepatitis C / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012725:Sexual Behavior; D012747:Sexual Partners; D013548:Sweden
D000914:Antibodies, Viral