Herpes simplex virus interstitial nephritis in a renal allograft.
We report a 35-year-old woman who developed herpes simplex virus (HSV) type 1 interstitial nephritis following a cadaveric renal transplant. Transplant function was poor and a transplant nephrectomy was performed 23 days post-transplant. Histological changes characteristic of herpes virus infection were seen on the renal biopsy with positive immunoperoxidase staining for HSV. HSV 1 was cultured from the transplant nephrectomy specimen.
Silbert
P L
PL
Department of Nephrology, Royal Perth Hospital, Australia.
Matz
L R
LR
Christiansen
K
K
Saker
B M
BM
Richardson
M
M
D000328:Adult; D002102:Cadaver; D005260:Female; D006561:Herpes Simplex / Q000473:pathology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007668:Kidney / Q000382:microbiology; D016030:Kidney Transplantation / Q000473:pathology*; D009392:Nephrectomy; D009395:Nephritis, Interstitial / Q000209:etiology*; D012086:Reoperation; D018139:Simplexvirus / Q000302:isolation & purification; D013997:Time Factors