Potential compounds for monitoring method performance in the determination of selected organochlorine pesticides and polychlorinated biphenyls in human serum.
Four compounds--2,2', 3,4'-tetrachlorobiphenyl, decachlorodiphenylether, 1,1-dichloro-2,2-bis(p-ethylphenyl)ethane, and dichlorobenzophenone--are recommended for monitoring the within-sample behavior of an analytical method that quantifies chlorinated pesticides and polychlorinated biphenyls (such as Aroclor 1260) in serum using packed column gas chromatography with electron capture detection. Percent recoveries of these surrogates averaged greater than 80%, except with dichlorobenzophenone, which had an average recovery of greater than 70%.
Burse
V W
VW
Division of Environmental Health Laboratory Sciences, Centers for Disease Control, Atlanta, GA 30333.
McClure
P C
PC
Korver
M P
MP
Head
S L
SL
Needham
L L
LL
D000970:Antineoplastic Agents / Q000097:blood; D001577:Benzophenones / Q000097:blood; D002623:Chemistry Techniques, Analytical / Q000379:methods; D002849:Chromatography, Gas / Q000379:methods; D003634:DDT / Q000097:blood; D003632:Dichlorodiphenyldichloroethane / Q000031:analogs & derivatives / Q000097:blood; D055768:Halogenated Diphenyl Ethers; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000097:blood; D007306:Insecticides / Q000097:blood*; D017633:Magnesium Silicates; D010647:Phenyl Ethers / Q000097:blood; D011078:Polychlorinated Biphenyls / Q000097:blood*; D012015:Reference Standards; D058428:Silica Gel; D012824:Silicic Acid; D012822:Silicon Dioxide
D000970:Antineoplastic Agents; D001577:Benzophenones; D055768:Halogenated Diphenyl Ethers; D006843:Hydrocarbons, Chlorinated; D007306:Insecticides; D017633:Magnesium Silicates; D010647:Phenyl Ethers; C005013:Florisil; D012824:Silicic Acid; C065092:decachlorodiphenyl ether; C065091:2,2',3,4'-tetrachlorobiphenyl; C001870:nonachlor; C004759:4,4'-dichlorobenzophenone; D058428:Silica Gel; C005292:perthane; D012822:Silicon Dioxide; D003634:DDT; D011078:Polychlorinated Biphenyls; D003632:Dichlorodiphenyldichloroethane