title: [Radionuclide studies of the early stage of chronic interstitial pneumonitis].
abstract: Radionuclide studies for the interstitial lung disease were surveyed in this article. On the ventilation-perfusion study, high V/Q mismatches are seen in advanced stage. A bolus inhalation method of small amount of Kr-81 m gas is useful to detect the impairment of thoraco-pulmonary compliance in the early stage of chronic interstitial pneumonitis (CIP). Ga-67 scintigraphy is indispensable for early detection and assessing the activity of CIP. During the last few years, the assessment of epithelial permeability using Tc-99m-DTPA is performed to evaluate morphological damage of pulmonary parenchyma in interstitial pulmonary diseases. Clinical significance of I-123-IMP scintigraphy was also surveyed.
authors.affiliation: Department of Radiology, Jikei University School of Medicine.
authors.forename: R
authors.initials: R
authors.lastname: Kawai
authors.forename: Y
authors.initials: Y
authors.lastname: Mori
authors.forename: K
authors.initials: K
authors.lastname: Kawakami
mesh_terms: D000662:Amphetamines; D005710:Gallium Radioisotopes; D006801:Humans; D007457:Iodine Radioisotopes; D020367:Iofetamine; D015609:Organotechnetium Compounds; D004369:Pentetic Acid; D011658:Pulmonary Fibrosis / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging; D016284:Technetium Tc 99m Pentetate; D013997:Time Factors
chemical_list: D000662:Amphetamines; D005710:Gallium Radioisotopes; D007457:Iodine Radioisotopes; D015609:Organotechnetium Compounds; D004369:Pentetic Acid; D020367:Iofetamine; D016284:Technetium Tc 99m Pentetate