A new cytokine receptor superfamily.
The amino acid sequences of several, recently cloned cytokine receptors show significant homologies, primarily in their extracellular, ligand-binding domains. With one exception, their cognate cytokines mediate biological activities on a variety of hematopoietic cell types; thus we have designated the receptors as the hematopoietic receptor superfamily.
Cosman
D
D
Immunex Corporation, Seattle, WA 98101.
Lyman
S D
SD
Idzerda
R L
RL
Beckmann
M P
MP
Park
L S
LS
Goodwin
R G
RG
March
C J
CJ
D000595:Amino Acid Sequence; D000818:Animals; D001685:Biological Factors / Q000378:metabolism*; D016207:Cytokines; D006801:Humans; D008969:Molecular Sequence Data; D011487:Protein Conformation; D011956:Receptors, Cell Surface / Q000145:classification / Q000378:metabolism*; D011971:Receptors, Immunologic / Q000145:classification / Q000378:metabolism*; D012689:Sequence Homology, Nucleic Acid
D001685:Biological Factors; D016207:Cytokines; D011956:Receptors, Cell Surface; D011971:Receptors, Immunologic