Nucleocapsid, nuclear association, and genome location of the herpes simplex virus type 2 38-kD DNA-binding protein.
A previously-described herpes simplex virus type 2 DNA-binding protein with a molecular size of 38 kD has been further characterized. Using purified nucleocapsids, a DNase release assay, and intertypic recombinants, this protein was found to be a component of the nucleocapsid, intimately associated with the nuclear matrix, and encoded between 0.605 and 0.720 on the herpes simplex virus type 2 genome.
Burdett
L A
LA
Virology Laboratory, Pennsylvania State University, University Park.
Docherty
J J
JJ
Howett
M K
MK
D000818:Animals; D002213:Capsid / Q000032:analysis*; D002478:Cells, Cultured; D006224:Cricetinae; D004268:DNA-Binding Proteins / Q000032:analysis* / Q000235:genetics; D004591:Electrophoresis, Polyacrylamide Gel; D005814:Genes, Viral; D015151:Immunoblotting; D015530:Nuclear Matrix / Q000382:microbiology; D010957:Plasmids / Q000235:genetics; D012333:RNA, Messenger / Q000235:genetics; D018139:Simplexvirus / Q000032:analysis*; D014709:Vero Cells; D014758:Viral Core Proteins / Q000032:analysis*; D014764:Viral Proteins / Q000032:analysis* / Q000235:genetics
D004268:DNA-Binding Proteins; D012333:RNA, Messenger; D014758:Viral Core Proteins; D014764:Viral Proteins