title: [The functional characteristics of the reproductive system in women who are heterozygous carriers of 21-hydroxylase deficiency].
abstract: This paper reports the results of evaluation of reproductive histories of 52 heterozygous female carriers of 21-hydroxylase deficiency who gave birth to children with classic congenital adrenocortical hyperplasia. Functional ACTH adrenal tests of these women were compared with those in a control group of noncarriers. Test findings are discussed with respect to the pathogenesis of reproductive tract disorders in the carriers of a mutant gene.
authors.forename: I G
authors.initials: IG
authors.lastname: Dzenis
authors.forename: E K
authors.initials: EK
authors.lastname: Brykova
authors.forename: V A
authors.initials: VA
authors.lastname: Bakharev
authors.forename: N D
authors.initials: ND
authors.lastname: Fanchenko
authors.forename: N V
authors.initials: NV
authors.lastname: Semenova
mesh_terms: D000304:Adrenal Cortex Function Tests; D000305:Adrenal Cortex Hormones / Q000097:blood; D000312:Adrenal Hyperplasia, Congenital / Q000235:genetics; D000324:Adrenocorticotropic Hormone; D000328:Adult; D005260:Female; D005817:Genetic Counseling; D006579:Heterozygote; D006801:Humans; D012098:Reproduction / Q000235:genetics / Q000502:physiology*; D013997:Time Factors
chemical_list: D000305:Adrenal Cortex Hormones; D000324:Adrenocorticotropic Hormone
vernacular_title: Osobennosti funktsii reproduktivnoĭ sistemy u zhenshchen--geterozigotnykh nositel'nits nedostatochnosti 21-gidroksilazy.