B19 parvovirus infection causing aplastic crisis in 3 out of 5 family members with hereditary spherocytosis.
B19 parvovirus infection is a principal cause of transient bone marrow suppression in patients with chronic haemolytic anaemias. Acute infection is described in a family of five individuals with hereditary spherocytosis; three of them developed marked hypoplastic anaemia.
Murphy
P T
PT
Department of Haematology, Beaumont Hospital, Dublin.
O'Donnell
J R
JR
D000208:Acute Disease; D000293:Adolescent; D000741:Anemia, Aplastic / Q000209:etiology*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D010322:Parvoviridae Infections / Q000150:complications*; D013103:Spherocytosis, Hereditary / Q000150:complications*