Saintopin, a new antitumor antibiotic with topoisomerase II dependent DNA cleavage activity, from Paecilomyces.
Yamashita
Y
Y
Saitoh
Y
Y
Ando
K
K
Takahashi
K
K
Ohno
H
H
Nakano
H
H
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D001551:Benz(a)Anthracenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D004247:DNA / Q000378:metabolism*; D004250:DNA Topoisomerases, Type II / Q000187:drug effects* / Q000235:genetics; D005285:Fermentation; D006094:Gram-Positive Bacteria / Q000187:drug effects; D006367:HeLa Cells; D006801:Humans; D007941:Leukemia P388 / Q000188:drug therapy; D051379:Mice; D015394:Molecular Structure; D010143:Paecilomyces / Q000378:metabolism*; D012988:Soil Microbiology
D000903:Antibiotics, Antineoplastic; D001551:Benz(a)Anthracenes; C066552:saintopin; D004247:DNA; D004250:DNA Topoisomerases, Type II