[The biochemical characteristics and antibiotic resistance phenotypes of strains of H. influenza isolated from the CSF of patients with meningitis].
The paper reports on the biochemical characteristics and the antibiotic resistant phenotypes in 18 strains of H. influenza (17 b serotype and a strain of c serotype) isolated from the CSF of the patients with purulent meningitis. The following were found: --all the 16 viable strains have homogeneous biochemical characteristics, typical for H. influenza; --the viable strains were: 7 biotype, 4 biotype II, 1 biotype III, 3 biotype IV and 1 biotype VII; --68.8% of the strains had the following antibiotic resistant phenotypes: Ap, Km, Rf, ApKm, ApRf, ApKmTc, ApKmRfT and ApCmFrKmRfTc; --the strains of the biotypes II and IV have the highest resistance to antibiotics, as concerns frequency and phenotype; --the frequency of the resistant strains is of 56.2% for ampicilline, 18.7% for tetracycline, 31.2% for rifampicine and 6.2% for cholarmphenicol.
Mihancea
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Institutul Cantacuzino, Bucureşti.
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D000900:Anti-Bacterial Agents / Q000494:pharmacology; D004352:Drug Resistance, Microbial; D006193:Haemophilus influenzae / Q000187:drug effects / Q000302:isolation & purification / Q000378:metabolism*; D006801:Humans; D008583:Meningitis, Haemophilus / Q000134:cerebrospinal fluid / Q000382:microbiology*; D008826:Microbial Sensitivity Tests; D010641:Phenotype
D000900:Anti-Bacterial Agents
Caracteristicile biochimice şi fenotipurile de rezistenţă la antibiotice ale tulpinilor de H. influenzae izolate din LCR al bolnavilor cu meningită.