Malignant hyperthermia may be due to a defect in a large Ca2+ release channel protein.
Davies
K
K
Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford, UK.
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D015220:Calcium Channels / Q000378:metabolism*; D002888:Chromosomes, Human, Pair 19; D004198:Disease Susceptibility; D006801:Humans; D008305:Malignant Hyperthermia / Q000235:genetics* / Q000378:metabolism; D009154:Mutation; D011950:Receptors, Cholinergic / Q000235:genetics* / Q000378:metabolism; D019837:Ryanodine Receptor Calcium Release Channel
D015220:Calcium Channels; D011950:Receptors, Cholinergic; D019837:Ryanodine Receptor Calcium Release Channel; D002118:Calcium