False aneurysm infected by Aspergillus fumigatus: an unusual complication of aortofemoral bypass graft.
Two cases of Aspergillus fumigatus infection of aortobifemoral prosthetic grafts are reported. Both patients were treated successfully by excision of the infected prosthetic material, axillofemoral extra-anatomic bypass, and prolonged medical treatment. The patients received amphotericin B, 5-flucytosine and itraconazole until negative aspergillus serology was obtained (at 9 and 18 months, respectively). Later, repeat disobliteration procedures for thrombosis of the axillofemoral bypass were required. No recurrent aspergillus infection was found.
Nussaume
O
O
Service de Chirurgie Thoracique et Vasculaire, Hôpital Beaujon, Clichy, France.
Elzaabi
M
M
Icard
P
P
Branger
C
C
Bouttier
S
S
Andreassian
B
B
D000666:Amphotericin B / Q000627:therapeutic use; D000785:Aneurysm, Infected / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D000935:Antifungal Agents / Q000627:therapeutic use; D001012:Aorta, Abdominal / Q000601:surgery*; D001228:Aspergillosis / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D001232:Aspergillus fumigatus; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D005263:Femoral Artery / Q000601:surgery*; D005437:Flucytosine / Q000627:therapeutic use; D006801:Humans; D017964:Itraconazole; D007654:Ketoconazole / Q000031:analogs & derivatives / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged
D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B; D005437:Flucytosine; D007654:Ketoconazole