A new genome type of adenovirus 3 associated with severe lower acute respiratory infection in children.
Adenovirus 3 was found associated with ten cases of infantile lower acute respiratory infection in patients aged 2-18 months. Of these, five had a fatal outcome, with severe lung damage. Restriction enzyme analysis with Bam HI, Bcl I, Bgl II, Bst E II, Hind III, Sal I, Sma I, Xba I, and Xho I revealed the presence of the same genome type in all ten specimens. The genomic variant was different from those previously reported for serotype 3 and therefore was tentatively denominated 3f.
Kajon
A E
AE
BioSidus S.A., Buenos Aires, Argentina.
Murtagh
P
P
Garcia Franco
S
S
Freire
M C
MC
Weissenbacher
M C
MC
Zorzópulos
J
J
D000208:Acute Disease; D000257:Adenoviridae Infections / Q000209:etiology*; D000258:Adenovirus Infections, Human / Q000209:etiology*; D000260:Adenoviruses, Human / Q000235:genetics; D002478:Cells, Cultured; D004279:DNA, Viral / Q000235:genetics; D005260:Female; D006801:Humans; D007223:Infant; D008171:Lung Diseases / Q000209:etiology*; D008297:Male; D015183:Restriction Mapping
D004279:DNA, Viral