Imipramine binding in depressed patients with psychogenic pain.
Imipramine binding to platelet membranes from depressed patients was analyzed. The patients were divided into two groups: one with depression alone, another with depression and psychogenic pain. The depressed patients with psychogenic pain had lower imipramine binding than the depressed patients without pain.
Mellerup
E T
ET
Psychiatric Department, Righospitalet, Copenhagen, Denmark.
Dam
H
H
Kim
M Y
MY
Loldrup
D
D
Plenge
P
P
Rosenberg
R
R
Schepelern
S
S
D001792:Blood Platelets / Q000378:metabolism*; D002352:Carrier Proteins; D003866:Depressive Disorder / Q000097:blood* / Q000523:psychology; D005260:Female; D006801:Humans; D007099:Imipramine / Q000493:pharmacokinetics*; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000097:blood* / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D011602:Psychophysiologic Disorders / Q000097:blood* / Q000523:psychology; D011955:Receptors, Drug; D017981:Receptors, Neurotransmitter / Q000378:metabolism*
D002352:Carrier Proteins; D011955:Receptors, Drug; D017981:Receptors, Neurotransmitter; C027775:imipramine receptor; D007099:Imipramine