[Assaying the SCF platelets cyclic nucleotides of schizophrenics and analyzing its correlation with pathopschological factors].
The experiment adopted radioimmunoassay to assay CSF, platelets cAMP cGMP levels of a group of Schizophrenia patients, and made a correlation analysis between the cAMP, cGMP and the evaluated factor scores of BPRS and SCL-90. The results showed: (1)CSF cAMP level of Schizophrenics was significantly higher than normal controls; (2)There was a significantly positive correlation between CSF cAMP and BPRS factor 1, a significantly negative correlation between platelets cAMP and BPRS factor 3, a significantly positive correlation between CSF cAMP and SCL-90 factor 5,8. The paper discussed the similarities and differences between the results of this experiment and the former studies.
Kang
W H
WH
Department of Psychiatry First Teaching Hospital Xian Medical University.
D000293:Adolescent; D000328:Adult; D001792:Blood Platelets / Q000737:chemistry*; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D000242:Cyclic AMP / Q000378:metabolism*; D006152:Cyclic GMP / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000453:epidemiology / Q000378:metabolism*; D012565:Schizophrenic Psychology
D000242:Cyclic AMP; D006152:Cyclic GMP