title: Emergence of aminoglycoside resistance genes aadA and aadE in the genus Campylobacter.
abstract: Resistance to streptomycin or spectinomycin or both in five Campylobacter coli strains, two Campylobacter jejuni strains, and a Campylobacter-like strain was studied by enzymatic assays and dot blot hybridization. Resistance was due to 6- or 3",9-aminoglycoside adenylyltransferases and to new types of phospho- and adenylyltransferases.
authors.affiliation: Unité des Agents Antibactériens, Institut Pasteur, Paris, France.
authors.forename: H
authors.initials: H
authors.lastname: Pinto-Alphandary
authors.forename: C
authors.initials: C
authors.lastname: Mabilat
authors.forename: P
authors.initials: P
authors.lastname: Courvalin
mesh_terms: D002167:Campylobacter / Q000187:drug effects / Q000235:genetics*; D004269:DNA, Bacterial / Q000235:genetics; D004352:Drug Resistance, Microbial / Q000235:genetics; D005798:Genes, Bacterial / Q000502:physiology*; D008826:Microbial Sensitivity Tests; D009693:Nucleic Acid Hybridization; D009713:Nucleotidyltransferases / Q000235:genetics; D000198:Spectinomycin / Q000494:pharmacology*; D013307:Streptomycin / Q000494:pharmacology*
chemical_list: D004269:DNA, Bacterial; D000198:Spectinomycin; D009713:Nucleotidyltransferases; C020658:glutamine-synthetase adenylyltransferase; D013307:Streptomycin