title: [Clinical analysis of 418 patients with Wilson's disease in traditional Chinese medicine and Western medicine therapy].
abstract: From 1974 to 1988, 418 cases of Wilson's disease were treated with TCM-WM in our hospital. 147 cases were of Wilson's type; 149 cases were of pseudosclerosis type; 40 cases were of abdominal and hepatocerebral type; 21 cases were of choreoathetosis type and 21 cases of other types. After a course of treatment for 3 to 6 months, 103 patients showed marked improvement and 286 made some improvement, but no effect was found in 22 patients and 7 deaths were observed. The results were as follows: (1) The mortality in the severe and moderate groups were significantly higher than the mild (P less than 0.05) and the marked effective rate was less than the latter (P less than 0.01). (2) The marked effective rate was lower in abdominal and hepatocerebral type, and no significant difference was found in recovery rate between Wilson's type and pseudosclerosis type.
authors.affiliation: Department of Neurology, Affiliated Hospital of Anhui of College of TCM, Hefei.
authors.forename: R
authors.initials: R
authors.lastname: Yang
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006527:Hepatolenticular Degeneration / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010396:Penicillamine / Q000627:therapeutic use*; D004113:Succimer / Q000627:therapeutic use*; D013431:Sulfates / Q000627:therapeutic use; D013438:Sulfhydryl Compounds / Q000627:therapeutic use*; D015032:Zinc / Q000627:therapeutic use; D019287:Zinc Sulfate
chemical_list: D004365:Drugs, Chinese Herbal; D013431:Sulfates; D013438:Sulfhydryl Compounds; D019287:Zinc Sulfate; D004113:Succimer; D010396:Penicillamine; D015032:Zinc