title: Ultrasonic imaging of the nonlinear parameter B/A: simulation studies to evaluate phase and frequency modulation methods.
abstract: This paper presents a method for imaging the nonlinear parameter B/A. It is based on measuring phase shift and frequency shift of a high frequency acoustic probe wave by a low frequency acoustic pump wave. These measurements yield the real and the imaginary parts of the Fourier component of the distribution B/A at the wave number of the pump wave. We also derive the necessary set of wave numbers of the pump wave which must be employed to accurately image the B/A parameter. We show that these wave numbers are a function of sampling period and sampling number. Simulations of the imaging method show that the proposed method in this paper leads to more accurate imaging of B/A than the earlier method.
authors.affiliation: Department of Physiology and Biophysics, Mayo Clinic/Foundation, Rochester, MN 55905.
authors.forename: D
authors.initials: D
authors.lastname: Kim
authors.forename: J F
authors.initials: JF
authors.lastname: Greenleaf
authors.forename: C M
authors.initials: CM
authors.lastname: Sehgal
mesh_terms: D000818:Animals; D005583:Fourier Analysis; D006801:Humans; D008961:Models, Structural; D014463:Ultrasonography / Q000379:methods*