Calcium activates glucose-6-phosphatase in intact rat hepatic microsomes.
The effects of Ca2+ on the microsomal glucose-6-phosphatase activity were investigated. Evidence is provided that increases by Ca2+ in both the pyrophosphatase and the glucose-6-phosphate-hydrolysing activities are due to an increase in microsomal transport capacity of T2, the phosphate/pyrophosphate-transport protein.
Waddell
I D
ID
Department of Child Health, Ninewells Hospital and Medical School, University of Dundee, Scotland, U.K.
Gibb
L
L
Burchell
A
A
D000818:Animals; D002118:Calcium / Q000494:pharmacology*; D003921:Diabetes Mellitus, Experimental / Q000201:enzymology; D004789:Enzyme Activation; D005215:Fasting; D005952:Glucose-6-Phosphatase / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology*; D008954:Models, Biological; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values
D005952:Glucose-6-Phosphatase; D002118:Calcium