Campylobacter pylori: a new pathogen.
There is now considerable evidence suggesting that C. pylori is a human pathogen. The strong association between C. pylori and gastroduodenal disease is well documented. A number of hypotheses have been suggested for the pathogenic mechanisms of C. pylori-induced gastroduodenal disease, including the production of cytotoxins and the mechanical disruption of the epithelium. At the present time, treatment with a combination of antimicrobial agents eradicates the infection in approximately 50% of cases. Until an ideal therapeutic regimen is available, antimicrobial therapy is recommended only for those patients who continue to be symptomatic following 6 to 8 weeks of treatment with an H2-receptor.
Czinn
S J
SJ
Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, Ohio.
Speck
W T
WT
D000818:Animals; D002167:Campylobacter / Q000472:pathogenicity*; D002169:Campylobacter Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D004195:Disease Models, Animal; D005756:Gastritis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D010437:Peptic Ulcer / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*