title: [The PIG-anchoring defect of lymphocyte populations in paroxysmal nocturnal hemoglobinuria].
abstract: Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by a defect expression of phosphatidylinositolglycan-(PIG-)linked surface molecules. This deficiency has been demonstrated for cells of myeloid origin so far, but not for lymphocytes. In these studies we examined the defect on lymphocyte subpopulations.
authors.affiliation: Medizinische Hochschule Hannover, Abteilung Immunologie und Transfusionsmedizin.
authors.forename: J
authors.initials: J
authors.lastname: Schubert
authors.forename: P
authors.initials: P
authors.lastname: Uciechowski
authors.forename: P
authors.initials: P
authors.lastname: Delany
authors.forename: R E
authors.initials: RE
authors.lastname: Schmidt
mesh_terms: D005455:Fluorescent Antibody Technique; D017261:Glycosylphosphatidylinositols; D006457:Hemoglobinuria, Paroxysmal / Q000097:blood*; D006801:Humans; D008214:Lymphocytes / Q000473:pathology*; D010716:Phosphatidylinositols / Q000172:deficiency*; D011134:Polysaccharides / Q000172:deficiency*
chemical_list: D017261:Glycosylphosphatidylinositols; D010716:Phosphatidylinositols; D011134:Polysaccharides
vernacular_title: Der PIG-Verankerungsdefekt auf Lymphozytenpopulationen bei paroxysmaler nächtlicher Hämoglobinurie.