title: Reconstruction of the middle ear with hydroxylapatite implants: long-term results.
abstract: The results are reported of reconstructions of the middle ear with hydroxylapatite implants performed between 1980 and 1986 with an average follow-up of 5 years. The findings concern 120 canal wall prostheses made of hydroxylapatite. It was possible to reconstruct a radical cavity with a new ear canal. The results obtained with ossiculoplasty in 170 patients are reported. In patients lacking an incus, an incus prosthesis made of hydroxylapatite gave air-bone gap closure to within 20 dB in 83.3% of the patients. Extrusion was not observed. In cases with the stapes superstructure and incus both missing, an incus/stapes prosthesis made of hydroxylapatite gave an air-bone gap closure to within 20 dB in 75.7% of the cases, when used as an assembly. Extrusion was not observed. When the prosthesis was used as a columella, the results were less favorable (41.1%), and two prostheses were extruded during the postoperative control period. Recurrent cholesteatoma was not seen in cases in which eradication and reconstruction were staged.
authors.affiliation: Department of Otorhinolaryngology, University Hospital Leiden, The Netherlands.
authors.forename: J J
authors.initials: JJ
authors.lastname: Grote
mesh_terms: D000293:Adolescent; D000328:Adult; D001672:Biocompatible Materials; D002516:Ceramics; D002648:Child; D002781:Cholesteatoma / Q000601:surgery; D017886:Durapatite; D004424:Ear Canal / Q000601:surgery*; D004427:Ear Diseases / Q000601:surgery; D004429:Ear Ossicles / Q000601:surgery*; D005500:Follow-Up Studies; D034381:Hearing Loss / Q000601:surgery; D006801:Humans; D006882:Hydroxyapatites; D007188:Incus / Q000601:surgery*; D008875:Middle Aged; D009998:Ossicular Prosthesis; D010034:Otitis Media with Effusion / Q000601:surgery; D011474:Prosthesis Design; D013201:Stapes Surgery; D014432:Tympanic Membrane / Q000293:injuries
chemical_list: D001672:Biocompatible Materials; D006882:Hydroxyapatites; D017886:Durapatite