Is human immunodeficiency virus (HIV) rather than cytomegalovirus the cause of retinitis and colitis in HIV-infected patients?
In the absence of proof that cytomegalovirus is the cause of colitis and retinitis in human immunodeficiency virus (HIV)-infected patients, it is proposed that HIV plays a direct role in the causation of these diseases. Clinical and epidemiologic evidence is cited to support this hypothesis. A direct role for HIV in the etiology of retinitis and colitis in HIV-infected patients could have important implications for antiviral chemotherapy in these diseases.
Morris
D J
DJ
Department of Pathological Sciences, University of Manchester Medical School, United Kingdom.
D003092:Colitis / Q000209:etiology*; D003587:Cytomegalovirus / Q000502:physiology; D003586:Cytomegalovirus Infections / Q000150:complications*; D006678:HIV / Q000502:physiology*; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D012173:Retinitis / Q000209:etiology*