title: Structure and composition of canine urinary calculi.
abstract: The chemical constituents of 171 specimens of canine urinary calculi have been analysed by infrared spectroscopy. The analysis revealed that 46 per cent of the total contained struvite as the major component; 26 per cent contained cystine; 16 per cent were found to be composed of whewellite and, or, weddellite; 8 per cent of urates; 3 per cent of calcium phosphate (apatite and, or, brushite) and 1 per cent of silica. A series of selected samples was also studied by scanning electron microscopy and energy dispersive X-ray analysis (EDAX). This examination revealed structures similar to human stones. Potassium and complex urates containing two or more cations were commonly found in many areas of ammonium urate and sodium urate calculi. Moreover, EDAX analysis detected a calcium enriched urate in several zones of urate calculi.
authors.affiliation: Departamento de Patología Animal II, Facultad de Veterinaria, Universidad Complutense de Madrid, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Escolar
authors.forename: J
authors.initials: J
authors.lastname: Bellanato
authors.forename: J A
authors.initials: JA
authors.lastname: Medina
mesh_terms: D000367:Age Factors; D000818:Animals; D001947:Breeding; D002129:Calcium Oxalate / Q000032:analysis; D002130:Calcium Phosphates / Q000032:analysis; D003553:Cystine / Q000032:analysis; D004283:Dog Diseases; D004285:Dogs; D004577:Electron Probe Microanalysis; D005260:Female; D008274:Magnesium / Q000032:analysis; D017616:Magnesium Compounds; D008297:Male; D008855:Microscopy, Electron, Scanning; D010710:Phosphates / Q000032:analysis; D012737:Sex Factors; D012822:Silicon Dioxide / Q000032:analysis; D013054:Spectrophotometry, Atomic; D013055:Spectrophotometry, Infrared; D000069877:Struvite; D014527:Uric Acid / Q000032:analysis; D014545:Urinary Calculi / Q000737:chemistry / Q000648:ultrastructure / Q000662:veterinary*
chemical_list: D002130:Calcium Phosphates; D017616:Magnesium Compounds; D010710:Phosphates; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; D002129:Calcium Oxalate; D014527:Uric Acid; D003553:Cystine; C485838:calcium phosphate, monobasic, anhydrous; D012822:Silicon Dioxide; C020243:calcium phosphate; D000069877:Struvite; D008274:Magnesium; C485829:calcium phosphate, dibasic, anhydrous