[The demonstration of human papillomavirus DNA in genital lesions with and without colposcopic atypism].
34 cellular suspensions from the vaginal part of women were examined for presence of HPV DNA of the types: 6, 11, 16 and 18--from a lesion and a healthy area--by filter in situ hybridization. The women were examined by colposcopy because of cervical lesions established macroscopically as well as for other various complaints. Cells were also investigated from women after undergone ablation treatment: diathermy coagulation, conization and hysterectomy on account of CIN. The data were compared with cytological, colposcopic and histological findings. The established presence of HPV DNA of high risk type 16 and 18 in some of the patients after operative treatment required continuous control of these women as well as examination of lower genital tract because of the discovered multicentricity of HPV infection.
Mincheva
A
A
Slavchev
B
B
Karag'ozov
I
I
Vasilev
N
N
Makaveeva
V
V
D000293:Adolescent; D000328:Adult; D003127:Colposcopy; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009693:Nucleic Acid Hybridization; D027383:Papillomaviridae; D011184:Postoperative Period; D011230:Precancerous Conditions / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D012307:Risk Factors; D014412:Tumor Virus Infections / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000453:epidemiology / Q000473:pathology; D014626:Vaginal Smears
D004279:DNA, Viral
Dokazvane na choveshka papilomavirusna DNK pri genitalni lezii sŭs i bez kolposkopski atipizŭm.