title: Results of conservative surgery for stage I lung cancer.
abstract: This paper reports our results with sublobar resections for stage I non small cell lung cancer. Sixty-one cases of wedge or segmental resection were compared with 517 standard resections (411 lobectomies and 106 pneumonectomies), performed during the years 1971-88. Operative mortality was 0% in the limited resection group and 4% (19/517) in the standard resection group; cancer recurrence was detected in 36% of both groups; actuarial survival at 5 years was 55% versus 48% overall. In 28 patients with pre-existing cardiac or pulmonary co-morbidity, limited resection yielded a similar 5-year survival than standard resection (53% vs 49%) with no perioperative deaths (0 vs 6%). Our data support the experience of other authors on conservative management of stage I lung cancer. Particularly in patients with concomitant cardio-pulmonary disease, previous cancer or small peripheral tumors, limited resection combined with adequate nodal staging may be as effective as standard lobar resection with respect to long term survival.
authors.affiliation: Department of Thoracic Surgery, Istituto Nazionale Tumori, Milan, Italy.
authors.forename: U
authors.initials: U
authors.lastname: Pastorino
authors.forename: M
authors.initials: M
authors.lastname: Valente
authors.forename: V
authors.initials: V
authors.lastname: Bedini
authors.forename: M
authors.initials: M
authors.lastname: Infante
authors.forename: L
authors.initials: L
authors.lastname: Tavecchio
authors.forename: G
authors.initials: G
authors.lastname: Ravasi
mesh_terms: D000328:Adult; D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D015996:Survival Rate