[Digital plethysmogram in women with climacteric disturbance after cold-water challenge test and effect of estrogen].
Immediately after a cold-water challenge test (C-W test) the pulse height to the digital plethysmogram descended (descent wave: D wave), and a congestion wave (C wave) occurred after the D wave. Then the recovery wave (R wave) continued after the C wave. The effects of estrogen on the digital plethysmogram under the C-W test are as follows. (1) The D wave was less than 25% in young women and women without climacteric disturbance. (2) The recovery rate of the C wave in young women was better than in climacteric women without climacteric disturbance. (3) The before value for A1B'1/B'1C1 in the C-W test of young women was 1.0, and the other values during the C-W test did not change significantly compared with the before values. (4) U-time rose only temporarily in the former case. In addition the recovery rate of the R wave after the administration of premarin in women with climacteric disturbance was 19.3%, and this was a significant improvement over the cases without administration. The recovery rate of the R wave in the same women after the administration of premarin and cercine increased to 48.3% (p less than 0.01). These data suggested that estrogen may be able to control the function of the autonomic nervous system in climacteric woman.
Katoh
K
K
Department of Obstetrics and Gynecology, Dokkyo University School of Medicine, Tochigi.
Watanabe
H
H
Ohtsuka
S
S
Ishikawa
K
K
Hoshiai
A
A
Kumasaka
T
T
D000293:Adolescent; D000328:Adult; D000375:Aging / Q000502:physiology; D001342:Autonomic Nervous System Diseases / Q000175:diagnosis*; D002979:Climacteric; D003080:Cold Temperature; D004967:Estrogens / Q000097:blood / Q000627:therapeutic use*; D004966:Estrogens, Conjugated (USP) / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D010991:Plethysmography
D004967:Estrogens; D004966:Estrogens, Conjugated (USP)