title: [An immunohistochemical study of estrogen receptors in thyroid carcinoma].
abstract: Estrogen receptors immunoreactivity (ER-IR) has been examined in 64 cases of human thyroid carcinomas. ER-IR was found to be located in the nucleus of cancer cells and was detected in 30 (57.7%) of 52 papillary carcinomas that were examined. Eleven cases showing a good number of ER-IR positive cancer cells revealed a lowered EORTC index of under 65, and no ER-IR was found in 12 anaplastic carcinomas. These findings indicate that ER-IR might generally bear a similar reciprocal relationship to the malignancy of a thyroid carcinoma.
authors.affiliation: 1st Dept. of Pathology, Hiroshima Univ. School of Med.
authors.forename: R
authors.initials: R
authors.lastname: Haruta
authors.forename: H
authors.initials: H
authors.lastname: Ito
authors.forename: N
authors.initials: N
authors.lastname: Takeichi
authors.forename: T
authors.initials: T
authors.lastname: Matsuyama
authors.forename: K
authors.initials: K
authors.lastname: Dohi
authors.forename: E
authors.initials: E
authors.lastname: Tahara
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D002291:Carcinoma, Papillary / Q000032:analysis / Q000473:pathology; D002467:Cell Nucleus / Q000032:analysis; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011960:Receptors, Estrogen / Q000032:analysis*; D012737:Sex Factors; D013964:Thyroid Neoplasms / Q000032:analysis* / Q000473:pathology
chemical_list: D011960:Receptors, Estrogen