title: [Gd-DOTA in musculoskeletal diseases].
abstract: T1-weighted images after the injection of Gd-DOTA, a new paramagnetic contrast medium, were compared with non-enhanced T2-weighted images in 42 consecutive cases of musculoskeletal pathology. In addition we evaluated the incidence of side effects. Enhanced T1-weighted images were superior in depicting the various parts of a lesion and the borders between the lesion and normal tissue or perifocal reaction. On the other hand the non-enhanced T2-weighted images better depicted the border between the perifocal reaction and normal tissue. In aggressive lesions, especially in malignant tumours, the two sequences are complementary. Enhanced T1-weighted images did not contribute significantly to assessing benign lesions. The incidence of side effects was acceptable and no severe reactions occurred.
authors.affiliation: Departement Medizinische Radiologie, Universitätsspital Zürich.
authors.forename: J
authors.initials: J
authors.lastname: Hodler
authors.forename: J
authors.initials: J
authors.lastname: Orellano
authors.forename: S
authors.initials: S
authors.lastname: Thurnher
authors.forename: B
authors.initials: B
authors.lastname: Marincek
authors.forename: G K
authors.initials: GK
authors.lastname: von Schulthess
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001847:Bone Diseases / Q000175:diagnosis*; D003287:Contrast Media; D005260:Female; D005682:Gadolinium; D006571:Heterocyclic Compounds / Q000009:adverse effects; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009135:Muscular Diseases / Q000175:diagnosis*; D009942:Organometallic Compounds / Q000009:adverse effects
chemical_list: D003287:Contrast Media; D006571:Heterocyclic Compounds; D009942:Organometallic Compounds; C050823:gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate; D005682:Gadolinium
vernacular_title: Gd-DOTA bei muskuloskelettalen Erkrankungen.