Nor-binaltorphimine is a reversible, noncompetitive opioid antagonist in the mouse vas deferens with high affinity for kappa receptors in monkey brain membranes.
Smith
C B
CB
Department of Pharmacology, University of Michigan, Ann Arbor 48109.
Medzihradsky
F
F
Hollingsworth
P J
PJ
DeCosta
B
B
Rice
K C
KC
Woods
J H
JH
D000818:Animals; D002540:Cerebral Cortex / Q000378:metabolism; D066298:In Vitro Techniques; D008253:Macaca mulatta; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D009271:Naltrexone / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D009292:Narcotic Antagonists; D011957:Receptors, Opioid / Q000378:metabolism; D017473:Receptors, Opioid, kappa; D013574:Synaptosomes / Q000378:metabolism; D014649:Vas Deferens / Q000187:drug effects
D009292:Narcotic Antagonists; D011957:Receptors, Opioid; D017473:Receptors, Opioid, kappa; C051844:norbinaltorphimine; D009271:Naltrexone