title: [Clinico-genealogical and phenotypic characteristics of patients with late sequelae of closed cranio-cerebral injuries].
abstract: As many as 100 patients with late sequelae of closed craniocerebral injuries (CCCI) and 50 healthy persons underwent a clinico-genealogical and phenotypic analysis. Multifactorial diseases (in particular essential hypertension and other cardiovascular diseases) which correlate with the clinical features of late sequelae of CCCI were noted to occur in the patients' pedigree significantly more often as compared to normal persons. The patients manifest a high frequency of the stigmas of dysembryogenesis. After CCCI part of them manifested certain hereditary diseases. Genetic risk factors should be taken into account in forecasting CCCI outcomes and planning follow up measures.
authors.forename: I I
authors.initials: II
authors.lastname: Shogam
authors.forename: E A
authors.initials: EA
authors.lastname: Pesochina
mesh_terms: D000293:Adolescent; D000328:Adult; D001924:Brain Concussion / Q000150:complications*; D002318:Cardiovascular Diseases / Q000209:etiology / Q000235:genetics*; D005260:Female; D005767:Gastrointestinal Diseases / Q000209:etiology / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000209:etiology / Q000235:genetics*; D010375:Pedigree; D010641:Phenotype; D013997:Time Factors
vernacular_title: Kliniko-genealogicheskaia i fenotipicheskaia kharakteristika bol'nykh s otdalennymi posledstviiami zakrytykh cherepno-mozgovykh travm.