title: [Chromosomal changes in primary myelodysplasias].
abstract: The data from literature on chromosome abnormalities in various subgroups of the myelodysplastic syndrome (according to FAB-classification) are presented. Special attention is paid to information about changes in the number and structure of chromosomes during the disease and their prognostic significance. The relation of definite chromosome aberrations to the clinical course and prognosis of the disease, in particular to its transformation into acute leukosis is under discussion.
authors.forename: L I
authors.initials: LI
authors.lastname: Iavorkovskiĭ
authors.forename: L Iu
authors.initials: LIu
authors.lastname: Riauzova
authors.forename: E Ia
authors.initials: EIa
authors.lastname: Soloveĭ
authors.forename: L L
authors.initials: LL
authors.lastname: Iavorkovskiĭ
mesh_terms: D002869:Chromosome Aberrations / Q000235:genetics*; D002872:Chromosome Deletion; D025063:Chromosome Disorders; D006801:Humans; D007621:Karyotyping; D009190:Myelodysplastic Syndromes / Q000235:genetics*; D011379:Prognosis; D014170:Transformation, Genetic
vernacular_title: Khromosomnye izmeneniia pri pervichnykh mielodisplaziiakh.