[Blood thymus hormone content in different types of neoplastic process and its changes as a result of chemotherapy and surgical removal of tumors].
Levels of thymic hormones in blood serum were found to decrease during the development of Guerin's carcinoma, methylcholanthrene- and DMBA-induced carcinogenesis, soft tissue sarcomas, mammary cancer, in children with tumors of the urinary-genital tract, that evidences for the suppression of the thymic endocrine function in neoplastic processes. A decrease in the level of substances, active in the test under study is not revealed in patients with different forms of leukemias. The tumour elimination normalizes the thymic endocrine function, while multiagent chemotherapy increases the insufficiency. The data obtained suggest the immunotherapy for malignant neoplasms with thymic hormones.
Nikol'skiĭ
I S
IS
Grinevich
Iu A
IuA
Bendiug
G D
GD
Martynenko
S V
SV
Ovsienko
V V
VV
Zamotaeva
G A
GA
Shevchenko
V P
VP
D000328:Adult; D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002648:Child; D006801:Humans; D007680:Kidney Neoplasms / Q000097:blood; D007938:Leukemia / Q000097:blood; D008297:Male; D008325:Mammary Neoplasms, Experimental / Q000097:blood; D009369:Neoplasms / Q000097:blood* / Q000188:drug therapy / Q000601:surgery; D051381:Rats; D012509:Sarcoma / Q000097:blood; D012513:Sarcoma, Experimental / Q000097:blood; D012983:Soft Tissue Neoplasms / Q000097:blood; D013951:Thymus Hormones / Q000097:blood*; D009396:Wilms Tumor / Q000097:blood
D000970:Antineoplastic Agents; D013951:Thymus Hormones
Soderzhanie gormonov timusa v krovi pri razlichnykh tipakh opukholevogo protsessa i ego izmenenie v rezul'tate khimioterapii i khirurgicheskogo udaleniia opukholi.