title: Conditioned responses to a taste conditioned stimulus paired with lithium chloride administration.
abstract: The present experiments examined whether behavioral conditioned responses (CRs) develop to lithium chloride (LiCl)-paired tastes and whether these CRs are similar to the behaviors that follow administration of the drug. Rats were exposed to a saccharin solution via intraoral infusions before being injected with either LiCl or saline. CRs were assessed after conditioning when the saccharin conditioned stimulus was delivered alone. The unconditioned response to LiCl delivery is a very distinctive posture that has been termed "lying-on-belly." The present study indicates that this behavior pattern also occurs after the delivery of a LiCl-paired taste solution. The similarity between these unconditioned and conditioned behaviors is consistent with the hypothesis that responses are conditioned during taste aversion acquisition and that CRs are similar to those that are generated by the drugs used in conditioning.
authors.affiliation: Department of Psychology, University of Washington, Seattle 98195.
authors.forename: C L
authors.initials: CL
authors.lastname: Meachum
authors.forename: I L
authors.initials: IL
authors.lastname: Bernstein
mesh_terms: D000818:Animals; D001070:Appetitive Behavior / Q000187:drug effects; D001143:Arousal / Q000187:drug effects; D001245:Association Learning / Q000187:drug effects*; D001362:Avoidance Learning / Q000187:drug effects*; D002712:Chlorides / Q000494:pharmacology*; D003214:Conditioning, Classical / Q000187:drug effects*; D006120:Grooming / Q000187:drug effects; D007274:Injections, Intraperitoneal; D008094:Lithium / Q000494:pharmacology*; D018021:Lithium Chloride; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D011187:Posture; D051381:Rats; D013649:Taste / Q000187:drug effects*
chemical_list: D002712:Chlorides; D008094:Lithium; D018021:Lithium Chloride