Poliovirus antibody in children from a paediatric hospital in Ibadan, Nigeria.
The immune status of 100 Nigerian children (ages 0-14) from a paediatric hospital in Ibadan, against poliovirus, after the administration of polyvalent oral poliovirus vaccine (types 1, 2 and 3) was determined using serum neutralisation test. High antibody titres were demonstrated in 78% of all the age groups tested. 57% of children under two years of age, 75% of those three to five years, and 100% of those above six years, had high poliovirus antibodies. 77% of male (47 out of 61) and 79% of female (31 out of 39) were positive. The difference between the sexes is not statistically significant (P greater than 0.05).
Williams
J O
JO
Department of Virology, College of Medicine, University of Ibadan, Nigeria.
David-West
T S
TS
D000293:Adolescent; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009500:Neutralization Tests; D009549:Nigeria / Q000453:epidemiology; D011051:Poliomyelitis / Q000453:epidemiology / Q000276:immunology; D017955:Poliovirus / Q000276:immunology*; D015995:Prevalence; D016036:Seroepidemiologic Studies
D000914:Antibodies, Viral