Oral treatment with itraconazole of aspergilloma in cavitary lung cancer.
We report a case of aspergilloma in a necrotic small cell lung cancer, where poor pulmonary function and performance status of the patient precluded surgical treatment. High dose Itraconazole, a new oral anti-mycotic drug, was given for 13 months. During this treatment there was a decrease of the fungus ball size and no haemoptysis. Moreover control of the aspergilloma allowed chemotherapeutic treatment of the underlying bronchocarcinoma.
Impens
N
N
Dept of pneumology, A.Z. VUB, Vrije Universiteit, Brussel, Belgium.
De Greve
J
J
De Beule
K
K
Meysman
M
M
De Beuckelaere
S
S
Schandevyl
W
W
D000935:Antifungal Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D001228:Aspergillosis / Q000150:complications / Q000188:drug therapy*; D001232:Aspergillus fumigatus; D018288:Carcinoma, Small Cell / Q000150:complications*; D006801:Humans; D017964:Itraconazole; D007654:Ketoconazole / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008172:Lung Diseases, Fungal / Q000150:complications / Q000188:drug therapy*; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged
D000935:Antifungal Agents; D017964:Itraconazole; D007654:Ketoconazole