The differential expression patterns of the mRNAs encoding beta subunits (beta 1, beta 2 and beta 3) of GABAA receptor in the olfactory bulb and its related areas in the rat brain.
The expression of mRNAs encoding different beta subunits (beta 1, beta 2 and beta 3) of GABAA receptor in the rat olfactory bulb and some of its related areas was investigated by in situ hybridization histochemistry. The beta 3 subunit mRNA was expressed in most of the cells in these regions such as periglomerular cells, tufted cells, mitral cells and granule cells in olfactory bulb, and the cells in anterior olfactory nucleus, piriform cortex and olfactory tubercle. However, only several kinds of these cells contained beta 2 subunit mRNA such as tufted cells and mitral cells of olfactory bulb, and the cells in anterior olfactory nucleus and piriform cortex. The beta 1 subunit mRNA was only detected in the mitral cells of olfactory bulb.
Zhang
J H
JH
Department of Anatomy II, Osaka University Medical School, Japan.
Sato
M
M
Noguchi
K
K
Tohyama
M
M
D000818:Animals; D001345:Autoradiography; D001921:Brain / Q000166:cytology / Q000378:metabolism*; D006651:Histocytochemistry; D008297:Male; D009474:Neurons / Q000378:metabolism; D009693:Nucleic Acid Hybridization; D009830:Olfactory Bulb / Q000166:cytology / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D011963:Receptors, GABA-A / Q000235:genetics*; D014018:Tissue Distribution
D012333:RNA, Messenger; D011963:Receptors, GABA-A