The yeast Yarrowia lipolytica has two, functional, signal recognition particle 7S RNA genes.
Cells containing a deletion of either the SCR1 or SCR2 genes, which code for the 7SL RNA component of the signal recognition particle (SRP) homologue, were found to be viable. Two independent approaches demonstrated that cells containing deletions of both genes were inviable. Therefore, Yarrowia lipolytica contains two (and only two) functional 7SL RNA genes.
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Laboratoire de Genetique, Centre de Biotechnologie Agro-Industrielle, INAPGt, Thiverval Grignon, France.
Yaver
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Beckerich
J M
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Ogrydziak
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Gaillardin
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D015139:Blotting, Southern; D002872:Chromosome Deletion; D005800:Genes, Fungal; D012331:RNA, Fungal / Q000235:genetics*; D015183:Restriction Mapping; D012261:Ribonucleoproteins / Q000235:genetics*; D004718:Saccharomycetales / Q000235:genetics* / Q000254:growth & development; D018271:Signal Recognition Particle; D014170:Transformation, Genetic
D012331:RNA, Fungal; D012261:Ribonucleoproteins; D018271:Signal Recognition Particle