Enzymes used in predicting high risk to colon cancer.
Attempts have been made to use enzyme assays primarily in tissue, to predict risk of colon cancer in high risk colon cancer families, and in patients with polyposis. Efforts have also been made to predict recurrence in surgically "cured" cancer patients. The use of thymidine kinase, ornithine decarboxylase, LDH isoenzymes, and other enzymes for these purposes will be reviewed.
Schwartz
M K
MK
Department of Clinical Chemistry, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.
D000818:Animals; D002272:Carcinoembryonic Antigen / Q000032:analysis; D004796:Clinical Enzyme Tests; D003110:Colonic Neoplasms / Q000175:diagnosis*; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D009955:Ornithine Decarboxylase / Q000378:metabolism; D010744:Phosphoric Monoester Hydrolases / Q000378:metabolism; D011237:Predictive Value of Tests; D011755:Pyrophosphatases / Q000378:metabolism; D012307:Risk Factors; D013937:Thymidine Kinase / Q000378:metabolism
D002272:Carcinoembryonic Antigen; D007770:L-Lactate Dehydrogenase; D013937:Thymidine Kinase; D010744:Phosphoric Monoester Hydrolases; D011755:Pyrophosphatases; C023117:thymidine-triphosphatase; D009955:Ornithine Decarboxylase