title: Simultaneous 99mTc double labelling of the hepatic reticuloendothelial system and of the red blood cells: a simplified method for the detection of liver hemangiomas.
abstract: Sonographic images of liver hemangioma are not specific. Causal detection imposes further investigations (angiography, CT, NMR) which are not always practicable. 99mTc-red blood cells study after 99mTc colloid liver scintigraphy has been already proposed. Ten patients with hepatic hemangiomas were evaluated by simplified, simultaneous in vivo double labelling of the reticuloendothelial system and red blood cells by means of successive i.v. injections of SnCl2, 99mTc colloid albumin and 99mTc-pertechnetate. Focal colloid defects filled with the labelled RBC were revealed in 9/10 liver hemangiomas. Angioscintigraphy showed decreased perfusion and RBC scintigraphy an increased blood volume in the focal colloid defects due to the hemangiomas.
authors.affiliation: Centro di Medicina Nucleare, Università di Cagliari, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Piga
authors.forename: L
authors.initials: L
authors.lastname: Satta
authors.forename: M
authors.initials: M
authors.lastname: Corrias
authors.forename: C
authors.initials: C
authors.lastname: Montaldo
authors.forename: G L
authors.initials: GL
authors.lastname: Loi
authors.forename: G
authors.initials: G
authors.lastname: Madeddu
mesh_terms: D000328:Adult; D000368:Aged; D004912:Erythrocytes; D005260:Female; D006392:Hemangioma, Cavernous / Q000000981:diagnostic imaging*; D006801:Humans; D007553:Isotope Labeling / Q000379:methods; D007728:Kupffer Cells; D008113:Liver Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013670:Sodium Pertechnetate Tc 99m; D013668:Technetium Tc 99m Aggregated Albumin
chemical_list: D013668:Technetium Tc 99m Aggregated Albumin; D013670:Sodium Pertechnetate Tc 99m