[Study of intrauterine cytomegaloviruses infection in pregnant women and fetuses].
Detection of cytomegaloviruses (CMV) DNA in urine samples from pregnant women and newborns' cord blood was done by DNA-DNA hybridization. 33.3% of pregnant women showed CMV DNA sequences in the 1-3 months, 36.4% in the 4-6 months and 38.2% in the 7-9 months. The results suggested that the CMV infection rate of pregnant women increased as time went on.75.0% women with history of abnormal pregnancies showed CMV in their urine and 30.4% newborns' cord blood was positive for CMV. It is apparently that CMV infection rate in women with history of abnormal pregnancies was much higher than that of normal pregnant women and the danger of miscarriage in pregnant women with primary CMV infection at early pregnancy increased. CMV congenital infection rate was also high in newborns.
Huang
S L
SL
Zhan-jiang Medical College.
D002681:China / Q000453:epidemiology; D003587:Cytomegalovirus; D003586:Cytomegalovirus Infections / Q000453:epidemiology* / Q000635:transmission; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D005315:Fetal Diseases / Q000453:epidemiology*; D006801:Humans; D008431:Maternal-Fetal Exchange; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*
D004279:DNA, Viral