title: Congenital melanocytic nevi with halo phenomenon: report of two cases and a review of the literature.
abstract: Verrucous congenital nevocellular nevi surrounded by a depigmented halo occurring in a 7-year-old boy and a 13-year-old girl were excised and the wounds closed primarily. Histopathologic studies revealed a striking arrangement of the inflammatory infiltrate in these halo nevi. A dense, band-like, lymphohistiocytic infiltrate was found only around and intermingled with A- and B-type nevomelanocytes in the upper dermis, whereas inflammatory infiltrates were completely absent from type C-nevomelanocytes in the lower parts of the reticular dermis. The literature is reviewed with particular consideration of congenital halo nevi.
authors.affiliation: Department of Dermatology, University of Vienna Medical School, Austria.
authors.forename: K
authors.initials: K
authors.lastname: Langer
authors.forename: K
authors.initials: K
authors.lastname: Konrad
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008543:Melanins; D008544:Melanocytes / Q000473:pathology; D009378:Neoplasms, Multiple Primary / Q000151:congenital* / Q000473:pathology; D009506:Nevus / Q000151:congenital* / Q000473:pathology; D009508:Nevus, Pigmented / Q000151:congenital* / Q000473:pathology; D012878:Skin Neoplasms / Q000151:congenital* / Q000473:pathology
chemical_list: D008543:Melanins