Membrane phospholipid composition, fluidity and phospholipase A2 activity of human hepatoma cell line HepG2.
1. Investigations have been carried out on the phospholipid composition, physical state and phospholipase A2 activity of plasma and microsomal membranes from HepG2 cells. 2. The results showed a great similarity in the physico-chemical properties of plasma and microsomal membranes from HepG2 cells. 3. The activity of phospholipase A2 was found to depend on the membrane physical state in both types of membranes.
Koumanov
K S
KS
Central Laboratory of Biophysics, Bulgarian Academy of Science, Sofia.
Momchilova-Pankova
A B
AB
Wang
S R
SR
Infante
R
R
D006528:Carcinoma, Hepatocellular / Q000201:enzymology*; D002462:Cell Membrane / Q000201:enzymology; D006801:Humans; D008113:Liver Neoplasms / Q000201:enzymology*; D008560:Membrane Fluidity; D008563:Membrane Lipids / Q000378:metabolism* / Q000502:physiology; D008861:Microsomes / Q000737:chemistry / Q000201:enzymology; D010741:Phospholipases A / Q000378:metabolism*; D054467:Phospholipases A2; D010743:Phospholipids / Q000378:metabolism* / Q000502:physiology; D014407:Tumor Cells, Cultured
D008563:Membrane Lipids; D010743:Phospholipids; D010741:Phospholipases A; D054467:Phospholipases A2