title: [Isolated ACTH deficiency: description of a clinical case].
abstract: A 34-year man was admitted to the hospital with symptoms of hypoglycemia. The endocrine investigations indicated adrenocortical insufficiency secondary to isolated ACTH deficiency: low ACTH and cortisol plasma levels, significant increase of cortisol following prolonged stimulation with depot tetracosactrin, normal secretory reserve of other anterior pituitary hormones. The absence of ACTH-response after corticotropin releasing hormone and insulin tolerance tests suggested a primary impairment of corticotropin cells.
authors.affiliation: Divisione di Medicina I, Ospedale S. Chiara, Trento.
authors.forename: W
authors.initials: W
authors.lastname: Spagnolli
authors.forename: G
authors.initials: G
authors.lastname: De Venuto
authors.forename: M
authors.initials: M
authors.lastname: Mattarei
authors.forename: C
authors.initials: C
authors.lastname: Ramponi
authors.forename: M
authors.initials: M
authors.lastname: Dal Follo
authors.forename: R
authors.initials: R
authors.lastname: Miori
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000172:deficiency*; D000328:Adult; D003346:Corticotropin-Releasing Hormone; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007003:Hypoglycemia / Q000175:diagnosis; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D011388:Prolactin / Q000097:blood; D013972:Thyrotropin / Q000097:blood
chemical_list: D000324:Adrenocorticotropic Hormone; D011388:Prolactin; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone; D013972:Thyrotropin; D003346:Corticotropin-Releasing Hormone; D011241:Prednisone
vernacular_title: Deficit isolato di ACTH: descrizione di un caso clinico.