The beta-subunit of the gastric H+/K(+)-ATPase can occur without the alpha-subunit.
The renal Na+/K(+)-ATPase and the gastric H+/K(+)-ATPase both contain alpha- and beta-subunits. We report here the identification and partial purification of a second population of the beta-subunit of the gastric H+/K(+)-ATPase, which has no accompanying alpha-subunit detectable by Coomassie blue staining or by Western blotting with monoclonal antibodies specific for the alpha-subunit.
Baldwin
G S
GS
Ludwig Institute for Cancer Research, Melbourne Tumour Biology Branch, PO Royal Melbourne Hospital, Victoria, Australia.
D000251:Adenosine Triphosphatases / Q000737:chemistry* / Q000302:isolation & purification; D000581:Amidohydrolases / Q000494:pharmacology; D000818:Animals; D015153:Blotting, Western; D002845:Chromatography; D005753:Gastric Mucosa / Q000201:enzymology*; D017506:H(+)-K(+)-Exchanging ATPase; D046911:Macromolecular Substances; D008970:Molecular Weight; D043524:Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; D013552:Swine
D046911:Macromolecular Substances; D000581:Amidohydrolases; D043524:Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; D000251:Adenosine Triphosphatases; D017506:H(+)-K(+)-Exchanging ATPase