Fulminant pulmonary edema following intravenous administration of radiocontrast media.
A 29-year-old woman who developed fulminant pulmonary edema several minutes after intravenous administration of radiocontrast media (RCM) is reported. The low pulmonary-capillary wedge pressure and the high protein concentration in pulmonary edema fluid indicated a noncardiogenic pulmonary edema related to increased lung vascular permeability. Laboratory studies showed a slight decrease of several complement components (C3, C4 and factor B) and a transient consumption coagulopathy. Potential pathophysiologic mechanisms involved in RCM- induced pulmonary edema are discussed.
Vandenplas
O
O
Service de Soins Intensifs, Cliniques Universitaires, St-Luc, Bruxelles.
Hantson
P
P
Dive
A
A
Mahieu
P
P
D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging; D002199:Capillary Permeability; D004827:Epilepsy / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008794:Metrizoic Acid / Q000009:adverse effects / Q000031:analogs & derivatives*; D011654:Pulmonary Edema / Q000139:chemically induced* / Q000503:physiopathology / Q000628:therapy; D014057:Tomography, X-Ray Computed
D008794:Metrizoic Acid; C021342:methylglucamine metrizoate