title: [The value of preoperative diagnosis before second-look laparotomy in ovarian cancer].
abstract: In a retrospective analysis, the diagnostic validity of computed tomography (CT), sonography (US), CA 125 and CEA serum levels in the detection of tumor-masses were evaluated in 135 patients with primary ovarian cancer. A second-look-laparotomy followed in each patient and the surgical-pathological findings were correlated to preoperative results. Sensitivity, specificity, positive and negative predictive value of the different methods were as follows: CT (n = 102) 70%, 65%, 68%, 67%, US (n = 97) 52%, 94%, 94%, 49%, CA 125 serum levels (n = 76) 55%, 100%, 100%, 58%, CEA serum levels (n = 40) 15%, 86%, 67%, 35%. CT, US and CA 125-serum levels appear to be suitable for routine control in ovarian cancer, but cannot replace the diagnostic value of a second-look-laparotomy.
authors.affiliation: Universitäts-Frauenklinik Göttingen.
authors.forename: H
authors.initials: H
authors.lastname: Meden
authors.forename: W
authors.initials: W
authors.lastname: Rath
authors.forename: D
authors.initials: D
authors.lastname: Ohlmeyer
mesh_terms: D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D002272:Carcinoembryonic Antigen / Q000032:analysis; D005260:Female; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000601:surgery; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000601:surgery; D010053:Ovary / Q000473:pathology; D012086:Reoperation; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen
vernacular_title: Die Wertigkeit der präoperativen Diagnostik vor der Second-look-Laparotomie beim Ovarialkarzinom.