Histogenesis of arterial intimal hyperplasia and atherosclerosis.
This article briefly reviews the histological evidence for the genesis of intimal hyperplasia and atherosclerosis in arteries. It concentrates upon the origin, structure and behaviour of vascular smooth muscle cells in the intimal (subendothelial) layer. The interactions between these intimal muscle cells, the endothelium and the blood are discussed with particular reference to their role in the histogenesis of intimal hyperplasia and atherosclerosis.
Tennant
M
M
Department of Anatomy and Human Biology, University of Western Australia, Nedlands.
Dilley
R J
RJ
McGeachie
J K
JK
Prendergast
F J
FJ
D001158:Arteries / Q000473:pathology*; D001161:Arteriosclerosis / Q000209:etiology* / Q000235:genetics / Q000473:pathology; D004730:Endothelium, Vascular / Q000378:metabolism / Q000473:pathology; D006801:Humans; D006965:Hyperplasia / Q000209:etiology / Q000473:pathology; D009000:Monocytes / Q000378:metabolism; D009131:Muscle, Smooth, Vascular / Q000473:pathology; D010641:Phenotype