Histopathologic grading of salivary gland neoplasms: III. Adenoid cystic carcinomas.
Histopathologic grading of adenoid cystic carcinomas can provide valuable prognostic information, particularly when the presence or absence of a solid growth architecture is noted. Other growth patterns, exemplified by a tubuloductal or cribriform-cylindromatous differentiation, are associated with a more protracted biologic course and less rapid mortality. A three-tiered grading system based on the three growth patterns of the carcinoma is presented.
Batsakis
J G
JG
Dept of Pathology, University of Texas M.D. Anderson Cancer Center, Houston, 77030.
Luna
M A
MA
el-Naggar
A
A
D003528:Carcinoma, Adenoid Cystic / Q000401:mortality / Q000473:pathology* / Q000556:secondary; D006801:Humans; D012468:Salivary Gland Neoplasms / Q000401:mortality / Q000473:pathology*; D015996:Survival Rate