The use of half-lives and associated confidence intervals in biological research.
The advantage of presenting experimental data in terms of half-life is discussed and a simple method of calculating a half-life from experimental data is described. Two methods of determining the confidence interval associated with the estimate of half-life are given and advantages and disadvantages of each method are discussed.
Bryan
M
M
Department of Statistics, Iowa State University, Ames 50011.
Zimmerman
J J
JJ
Berry
W J
WJ
D000704:Analysis of Variance; D000818:Animals; D016001:Confidence Intervals; D006207:Half-Life; D011558:Herpesvirus 1, Suid / Q000254:growth & development / Q000302:isolation & purification; D006793:Houseflies / Q000382:microbiology; D012044:Regression Analysis