[The ultrastructure and histochemical characteristics of the cells of malignant fibrous histiocytoma in rats].
Samples of tissue from malignant fibrous histiocytoma of rats induced by subcutaneous injection of paraffin pill-enclosed DMBA were studied for localization of acid phosphatase and non-specific esterases (15 samples) and cell ultrastructure (10). Tumours showed cellular heterogeneity consisting of 5 types of cells: histiocyte-like, fibroblast-like, giant multinuclear xanthomatous and undifferentiated. Acid phosphatase and non-specific esterases were found both in histiocyte-like and fibroblast-like cells which means that those enzymes are not the specific markers of tumors arising from monocytic-macrophagal system. Histochemical and ultrastructural features of experimental malignant fibrous histiocytoma were similar to those of its human analogue.
Pozharisskiĭ
K M
KM
Nikitin
A Iu
AIu
D015127:9,10-Dimethyl-1,2-benzanthracene; D000135:Acid Phosphatase / Q000378:metabolism; D000818:Animals; D004950:Esterases / Q000378:metabolism; D018219:Histiocytoma, Benign Fibrous / Q000139:chemically induced / Q000201:enzymology / Q000648:ultrastructure*; D006651:Histocytochemistry; D008297:Male; D008854:Microscopy, Electron; D051381:Rats; D012878:Skin Neoplasms / Q000139:chemically induced / Q000201:enzymology / Q000648:ultrastructure*
D015127:9,10-Dimethyl-1,2-benzanthracene; D004950:Esterases; D000135:Acid Phosphatase
Ul'trastruktura i gistokhimicheskie osobennosti kletok zlokachestvennoĭ fibroznoĭ gistiotsitomy u krys.