title: Preventive effect of aluminium citrate on silicosis.
abstract: Aluminium citrate (Al-cit) was shown to be biologically effective in preventing silicosis. A total of 917 cases selected from both engineering corps of railway and coalmines with stage 0 or 0+ by radiographs were studied. Cases were randomly divided into Al-cit treatment group and control group with continuing dust exposures. Workers in the treatment group were injected with Al-cit at a dose of 120 mg Al/year and these in the control group received a consolatant or nothing during the period of five years. The radiographic changes demonstrated that Al-cit showed clear-cut effects in both retardation of the dust-induced fibrosis and decrease of the morbidity of silicosis.
authors.affiliation: Department of Occupational Health, Beijing Medical University.
authors.forename: S Q
authors.initials: SQ
authors.lastname: Zou
authors.forename: H
authors.initials: H
authors.lastname: Liu
authors.forename: Y Y
authors.initials: YY
authors.lastname: Zhou
authors.forename: K Q
authors.initials: KQ
authors.lastname: Su
authors.forename: K Y
authors.initials: KY
authors.lastname: Qi
authors.forename: S M
authors.initials: SM
authors.lastname: Guan
authors.forename: S J
authors.initials: SJ
authors.lastname: Liu
mesh_terms: D000328:Adult; D000818:Animals; D002951:Citrates / Q000627:therapeutic use*; D019343:Citric Acid; D003031:Coal; D006801:Humans; D008297:Male; D008906:Mining; D011890:Railroads; D011897:Random Allocation; D051381:Rats; D012822:Silicon Dioxide; D012829:Silicosis / Q000209:etiology / Q000517:prevention & control*
chemical_list: D002951:Citrates; D003031:Coal; D019343:Citric Acid; D012822:Silicon Dioxide