Congenital multiple plaquelike glomus tumors.
We encountered two patients with congenital multiple plaquelike glomus tumors. These lesions were present at birth and enlarged with body growth, attaining a diameter of up to 13 cm. The diagnosis was confirmed by histologic and electron-microscopic examination, which revealed the typical changes of glomus tumors. Immunocytochemistry findings demonstrated the tumor cells to be vimentin- and alpha-smooth muscle-actin-positive and desmin-negative. On ultrastructural examination, typical dense bodies and attachment plaques were easily found within the tumor cells. Glomus cells were coated by a thick basal lamina.
Landthaler
M
M
Department of Dermatology, Ludwig-Maximilians Universität Munich, West Germany.
Braun-Falco
O
O
Eckert
F
F
Stolz
W
W
Dorn
M
M
Wolff
H H
HH
D002648:Child; D005918:Glomus Tumor / Q000032:analysis / Q000151:congenital* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D007381:Intermediate Filament Proteins / Q000032:analysis; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000032:analysis / Q000151:congenital* / Q000473:pathology; D012878:Skin Neoplasms / Q000032:analysis / Q000151:congenital* / Q000473:pathology
D007381:Intermediate Filament Proteins