Interaction between X-ray- and restriction endonuclease-induced lesions in the formation of chromosomal aberrations.
Experiments were performed to analyze the possible interaction between lesions induced by X-rays and restriction endonucleases in the production of chromosome-type exchanges. A stronger interaction was found between X-rays and the AluI-induced 'blunt termini' lesions than between X-rays and the BamHI-induced 'cohesive termini' lesions.
Tanzarella
C
C
Centro di Genetica Evoluzionistica del CNR, c/o Dipartimento Darwin, Università La Sapienza, Rome, Italy.
De Salvia
R
R
Degrassi
F
F
Fiore
M
M
Palitti
F
F
D000818:Animals; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000187:drug effects / Q000528:radiation effects*; D006224:Cricetinae; D004262:DNA Restriction Enzymes / Q000633:toxicity*; D015245:Deoxyribonuclease BamHI; D015252:Deoxyribonucleases, Type II Site-Specific; D009153:Mutagens
D009153:Mutagens; D004262:DNA Restriction Enzymes; D015245:Deoxyribonuclease BamHI; C024669:endodeoxyribonuclease AluI; D015252:Deoxyribonucleases, Type II Site-Specific