[Mechanisms of the development of immunodependent inflammation in silicosis].
Patients with uncomplicated silicosis were found to develop chronic immunodependent inflammation caused by an adjuvant effect of silica and characterized by autoimmune, histamine- and complement-dependent components. Reduced specific and non-specific antimicrobial defence underlies frequent complication of silicosis by tuberculosis and nonspecific infectious diseases of the bronchopulmonary system. A diagram showing the development of immunodependent inflammation in silicosis is presented.
Grishina
T I
TI
Alekseeva
O G
OG
Aĭzina
N L
NL
Volkova
A P
AP
Girdo
R G
RG
Loshchilov
Iu A
IuA
Sokolov
V V
VV
D001324:Autoantigens / Q000009:adverse effects* / Q000276:immunology; D001327:Autoimmune Diseases / Q000209:etiology*; D006801:Humans; D008168:Lung / Q000276:immunology*; D011791:Quartz / Q000009:adverse effects / Q000276:immunology*; D012822:Silicon Dioxide / Q000276:immunology*; D012829:Silicosis / Q000150:complications / Q000276:immunology*; D012830:Silicotuberculosis / Q000209:etiology*
D001324:Autoantigens; D011791:Quartz; D012822:Silicon Dioxide
Mekhanizmy razvitiia immunozavisimogo vospaleniia pri silikoze.