title: Effect of lithium chloride-induced aversion on appetitive and consummatory behavior.
abstract: The effect of lithium chloride-induced conditioned taste aversions on appetitive and consummatory behavior was determined. Rats were given access to a 0.1% saccharin solution for 15 min either in bottles or by infusion through an intraoral cannula. Bottle-fed rats given postprandial injections of lithium chloride showed greater aversion to saccharin than cannula-fed rats. During extinction, cannula-fed rats gradually recovered to control levels of intake, whereas bottle-fed rats continued to avoid the saccharin. These results suggest that lithium chloride affects appetitive behavior to a greater extent than it affects consummatory behavior.
authors.affiliation: Institute for the Study of Alcohol and Drug Dependence, Florida Atlantic University, Boca Raton 33431-0991.
authors.forename: D L
authors.initials: DL
authors.lastname: Wolgin
authors.forename: J V
authors.initials: JV
authors.lastname: Wade
mesh_terms: D000818:Animals; D001070:Appetitive Behavior / Q000187:drug effects*; D001245:Association Learning / Q000187:drug effects; D001362:Avoidance Learning / Q000187:drug effects*; D002712:Chlorides / Q000494:pharmacology*; D003214:Conditioning, Classical / Q000187:drug effects*; D003259:Consummatory Behavior / Q000187:drug effects*; D005108:Extinction, Psychological / Q000187:drug effects; D008094:Lithium / Q000494:pharmacology*; D018021:Lithium Chloride; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains; D013649:Taste / Q000187:drug effects
chemical_list: D002712:Chlorides; D008094:Lithium; D018021:Lithium Chloride