title: [Formation of iron complexes with ascorbic acid in physiological conditions in vitro and in tissue in vivo].
abstract: Rapid dissociated Fe(III)-ascorbic acid complexes are formed after the mixing of Fe(II) (100 mkM) with ascorbic acid (1 mM) at pH-7,4. As a result of these complexes formation Fe(II) concentration was decreased in solution, but o-phenantrolin addition or pH decreased up to 6.1 lead to the destruction of these complexes and reduction of iron up to Fe(II). Iron-ascorbic acid paramagnetic complexes were not observed in the perfused rat liver homogenate. Probably, these facts were due to the presence of other stronger reductants in the tissue.
authors.forename: A V
authors.initials: AV
authors.lastname: Kozlov
authors.forename: D Iu
authors.initials: DIu
authors.lastname: Egorov
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Vladimirov
authors.forename: O A
authors.initials: OA
authors.lastname: Azizova
mesh_terms: D000818:Animals; D001205:Ascorbic Acid / Q000378:metabolism*; D004578:Electron Spin Resonance Spectroscopy; D005290:Ferric Compounds / Q000378:metabolism; D005296:Ferrous Compounds / Q000378:metabolism; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D007501:Iron / Q000378:metabolism*; D007700:Kinetics; D008099:Liver / Q000378:metabolism*; D010084:Oxidation-Reduction; D010618:Phenanthrolines; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D005290:Ferric Compounds; D005296:Ferrous Compounds; D010618:Phenanthrolines; D007501:Iron; D001205:Ascorbic Acid
vernacular_title: Obrazovanie kompleksov zheleza s askorbinovoĭ kislotoĭ v fiziologicheskikh usloviiakh in vitro i v tkani in vivo.