[Change in the adenylate cyclase activity of the lymphocytes and thrombocytes in irradiated sheep].
Changes in basal and prostaglandin stimulated activity of adenylate cyclase in lymphocytes and platelets of irradiated sheep are phasic. In platelets adenylate cyclase activity is maximum on days 5 and 10 following irradiation, whereas in lymphocytes the enzyme activity is maximum on day 7. cAMP phosphodiesterase activity is slightly changed in platelets and increased in lymphocytes of exposed sheep.
Shevchenko
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AS
D000262:Adenylyl Cyclases / Q000097:blood*; D000527:Alprostadil / Q000494:pharmacology; D000818:Animals; D001792:Blood Platelets / Q000201:enzymology*; D000242:Cyclic AMP / Q000502:physiology; D005260:Female; D008214:Lymphocytes / Q000201:enzymology*; D008297:Male; D010727:Phosphoric Diester Hydrolases / Q000097:blood; D011833:Radiation Injuries, Experimental / Q000097:blood* / Q000201:enzymology; D012756:Sheep; D013268:Stimulation, Chemical
D000242:Cyclic AMP; D010727:Phosphoric Diester Hydrolases; D000262:Adenylyl Cyclases; D000527:Alprostadil
Izmenenie aktivnosti adenilattsiklazy v limfotsitakh i trombotsitakh obluchennykh ovets.