Isolated cytomegalovirus ileitis detected by colonoscopy.
Cytomegalovirus infections in immunocompromised patients mimic graft-versus-host disease by causing abdominal pain, watery diarrhea, and protein-losing enteropathy. The cases of three bone marrow transplant patients with diarrheal illness and biopsy-proven graft-vs.-host disease are reported. Isolated cytomegalovirus enteritis was subsequently identified by endoscopic examination and biopsy of the terminal ileum. All three improved with the eventual institution of 9-(1,3-dihydroxy-2-propoxymethyl) guanine. Ileoscopy is important in addition to colonoscopy in bone marrow transplant patients with diarrhea if cytomegalovirus enteritis is to be identified and appropriately treated.
Lepinski
S M
SM
Department of Medicine, University of Wisconsin, Madison.
Hamilton
J W
JW
D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects; D003113:Colonoscopy; D003586:Cytomegalovirus Infections / Q000175:diagnosis*; D003937:Diagnosis, Differential; D003967:Diarrhea; D005260:Female; D006086:Graft vs Host Disease / Q000175:diagnosis*; D006801:Humans; D007079:Ileitis / Q000175:diagnosis*; D008297:Male; D014456:Ulcer / Q000175:diagnosis