title: [Clinical study concerning of latamoxef concentration in the obstructed urinary tract].
abstract: Urinary LMOX concentration was studied in 18 patients with unilateral ureteral obstruction. The concentration of LMOX in the urine from the mild obstructed kidney was 124 to 2,140 micrograms/ml and 10 micrograms/ml in the severely obstructed ones. The difference was probably due to the intensity and the duration of the obstruction. The patient with 99mTc-DMSA renal uptake of less than 3% also had a urinary LMOX concentration of less than 7 micrograms/ml. The above results seem to show that 7 micrograms/ml in urinary LMOX concentration is a significant figure for treatment of UTI. 99mTc-DMSA renal uptake and renal echogram were used to estimate the excretion rate of antibiotics into the urine.
authors.affiliation: Department of Urology, Sendai Social Insurance Hospital.
authors.forename: Y
authors.initials: Y
authors.lastname: Suzuki
authors.forename: S
authors.initials: S
authors.lastname: Itoh
authors.forename: M
authors.initials: M
authors.lastname: Katoh
authors.forename: M
authors.initials: M
authors.lastname: Morita
authors.forename: Y
authors.initials: Y
authors.lastname: Fukushi
authors.forename: S
authors.initials: S
authors.lastname: Toyota
authors.forename: S
authors.initials: S
authors.lastname: Katoh
authors.forename: K
authors.initials: K
authors.lastname: Oikawa
authors.forename: S
authors.initials: S
authors.lastname: Orikasa
authors.forename: K
authors.initials: K
authors.lastname: Majima
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D006801:Humans; D007262:Infusions, Intravenous; D007668:Kidney / Q000378:metabolism; D008875:Middle Aged; D009070:Moxalactam / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000652:urine*; D015609:Organotechnetium Compounds; D011866:Radioisotope Renography; D004113:Succimer; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D014514:Ureteral Calculi / Q000150:complications / Q000378:metabolism; D014517:Ureteral Obstruction / Q000000981:diagnostic imaging / Q000378:metabolism*
chemical_list: D015609:Organotechnetium Compounds; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D004113:Succimer; D009070:Moxalactam