title: [Age-related immunodeficiencies of the neutrophilic granulocyte system].
abstract: Transitory age-associated deficiency of the granulocyte cationic proteins as a cause of a phagocytosis disturbance, loss of the phagocyte cell ability to kill phagocytosed bacteria is established. Quantitative indexes of myeloperoxidase content, elastase and catepsin G in the neutrophil granulocytes of newborns and laboratory animals are determined. Hypothesis is developed on the transitory age-associated immunodeficiencies of the neutrophil granulocyte system as one of the endogenic risk factors in the development of infectious diseases during early postnatal period.
authors.forename: V E
authors.initials: VE
authors.lastname: Pigarevskiĭ
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Mazing
authors.forename: V N
authors.initials: VN
authors.lastname: Kokriakov
mesh_terms: D000375:Aging / Q000097:blood*; D000818:Animals; D000831:Animals, Newborn; D001798:Blood Proteins / Q000032:analysis; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000097:blood*; D007231:Infant, Newborn; D007637:Keratoconjunctivitis / Q000097:blood; D008088:Listeriosis / Q000097:blood; D009504:Neutrophils / Q000378:metabolism*; D009195:Peroxidase / Q000097:blood; D010587:Phagocytosis / Q000502:physiology; D011817:Rabbits; D012697:Serine Endopeptidases / Q000097:blood
chemical_list: D001798:Blood Proteins; D009195:Peroxidase; D012697:Serine Endopeptidases
vernacular_title: Vozrastnye immunodefitsity sistemy neĭtrofil'nykh granulotsitov.