A nosocomial outbreak of epidemic keratoconjunctivitis due to adenovirus type 37.
An outbreak of epidemic keratoconjunctivitis occurred at the department of ophthalmology of a hospital in Yokohama, involving 14 inpatients, 12 outpatients, and 2 doctors. Adenovirus type 37 (Ad-37) was isolated from the conjunctival swab in 12 of 18 cases. In neutralization tests, the isolates showed some cross-reaction with adenovirus type 19 (Ad-19). The Ad-37 isolates were indistinguishable from each other and from the prototype Ad-37, but distinct from the prototype Ad-19 in the restriction endonuclease analysis of viral DNA.
Takeuchi
R
R
Division of Microbiology, Yokohama City Institute of Health, Kanagawa.
Nomura
Y
Y
Kojima
M
M
Uchio
E
E
Kobayashi
N
N
Matumoto
M
M
D000258:Adenovirus Infections, Human / Q000453:epidemiology*; D000260:Adenoviruses, Human / Q000235:genetics / Q000302:isolation & purification; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003228:Conjunctiva / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D004262:DNA Restriction Enzymes; D004279:DNA, Viral / Q000378:metabolism; D015828:Eye Infections, Viral / Q000453:epidemiology* / Q000382:microbiology; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D016130:Immunophenotyping; D007564:Japan / Q000453:epidemiology; D007637:Keratoconjunctivitis / Q000453:epidemiology* / Q000382:microbiology; D008875:Middle Aged; D009500:Neutralization Tests
D004279:DNA, Viral; D004262:DNA Restriction Enzymes