The catalytic activity of iron in synovial fluid as monitored by the ascorbate free radical.
Human synovial fluid, from a patient with synovitis disease, was examined by electron spin resonance spectroscopy for evidence of free radicals. The ascorbate free radical was observed and its intensity was affected by iron chelating agents, demonstrating that the iron in the synovial fluid is indeed available for oxidative catalysis.
Buettner
G R
GR
ESR Center, College of Medicine, University of Iowa, Iowa City 52242.
Chamulitrat
W
W
D001205:Ascorbic Acid / Q000032:analysis*; D003676:Deferoxamine / Q000494:pharmacology; D004578:Electron Spin Resonance Spectroscopy; D005609:Free Radicals; D006801:Humans; D007501:Iron / Q000378:metabolism*; D010084:Oxidation-Reduction; D004369:Pentetic Acid / Q000494:pharmacology; D013582:Synovial Fluid / Q000032:analysis*; D013586:Synovitis, Pigmented Villonodular / Q000378:metabolism
D005609:Free Radicals; D004369:Pentetic Acid; D007501:Iron; D003676:Deferoxamine; D001205:Ascorbic Acid