Detection of metabolites in body fluids and biological tissue by a 1D soft COSY technique.
With a semi-selective 1D COSY, related to the soft COSY sequence, metabolites with concentrations of a few millimolar can be detected, while highly abundant molecules as water or lipids are efficiently suppressed.
Stryjewski
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D
Institut für Organische Chemie, Universität Bremen, West Germany.
Oschkinat
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H
Leibfritz
D
D
D000818:Animals; D006801:Humans; D007773:Lactates / Q000097:blood; D008099:Liver / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008433:Mathematics; D009206:Myocardium / Q000378:metabolism; D011522:Protons; D011817:Rabbits; D051381:Rats
D007773:Lactates; D011522:Protons