Metabolism of 3 beta-hydroxycholest-5-en-26-oic acid in hamsters.
Metabolism of 26-hydroxycholesterol to 3 beta-hydroxychol-5-en-24-oic acid and other C24-bile acids has been expected to occur by way of 3 beta-hydroxycholest-5-en-26-oic acid in studies in vitro. 3 beta-Hydroxycholest-5-en-26-oic acid was infused intravenously into bile fistula hamsters and the following C24-bile acids were identified: 3 beta-hydroxychol-5-en-24-oic acid, lithocholic acid, chenodeoxycholic acid, and a small amount of cholic acid.
Ayaki
Y
Y
Department of Biochemistry, Medical School of Tottori University, Japan.
Kok
E
E
Javitt
N B
NB
D000818:Animals; D001646:Bile / Q000378:metabolism; D001647:Bile Acids and Salts / Q000378:metabolism; D002784:Cholesterol / Q000031:analogs & derivatives* / Q000378:metabolism; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D006224:Cricetinae; D008297:Male; D008647:Mesocricetus; D011865:Radioisotope Dilution Technique
D001647:Bile Acids and Salts; C029435:3-hydroxy-5-cholestenoic acid; D002784:Cholesterol