title: [The effect of creatine phosphate on reflex transmission in the normal spinal cord and under hypoxic conditions].
abstract: The effect of phosphocreatine on reflex transmission in the spinal cord was studied in rats in vivo and in vitro. Low concentrations (10(-8)-10(-6) M) of phosphocreatine facilitated while high concentrations (10(-4)-10(-3) M) inhibited the amplitude of mono- and polysynaptic reflexes. It was found that phosphocreatine decreases the inhibiting action of hypoxia on test responses and accelerates restoration of the reflex transmission in the spinal cord.
authors.forename: Iu P
authors.initials: IuP
authors.lastname: Limanskiĭ
authors.forename: Z A
authors.initials: ZA
authors.lastname: Tamarova
authors.forename: A I
authors.initials: AI
authors.lastname: Piliavskiĭ
authors.forename: V N
authors.initials: VN
authors.lastname: Oksamitnyĭ
authors.forename: S G
authors.initials: SG
authors.lastname: Khasabov
authors.forename: N V
authors.initials: NV
authors.lastname: Bulgakova
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D000860:Hypoxia / Q000503:physiopathology*; D066298:In Vitro Techniques; D010725:Phosphocreatine / Q000494:pharmacology*; D051381:Rats; D012018:Reflex / Q000187:drug effects* / Q000502:physiology; D012023:Reflex, Monosynaptic / Q000187:drug effects / Q000502:physiology; D013116:Spinal Cord / Q000187:drug effects* / Q000502:physiology; D009435:Synaptic Transmission / Q000187:drug effects* / Q000502:physiology
chemical_list: D010725:Phosphocreatine
vernacular_title: Vliianie kreatinfosfata na reflektornuiu peredachu v spinnom mozge v norme i v usloviiakh gipoksii.