Activation of mutagens by human cytochrome P-450 enzymes.
Guengerich
F P
FP
Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232.
Shimada
T
T
Iwasaki
M
M
Martin
M V
MV
D000478:Alkylation; D001426:Bacterial Proteins / Q000096:biosynthesis / Q000235:genetics; D001711:Biotransformation; D002273:Carcinogens / Q000378:metabolism; D003577:Cytochrome P-450 Enzyme System / Q000145:classification / Q000378:metabolism*; D004249:DNA Damage; D004790:Enzyme Induction; D006801:Humans; D007527:Isoenzymes / Q000378:metabolism*; D009153:Mutagens / Q000378:metabolism*; D010084:Oxidation-Reduction; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis; D013014:SOS Response, Genetics; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics; D001616:beta-Galactosidase / Q000096:biosynthesis
D001426:Bacterial Proteins; D002273:Carcinogens; D007527:Isoenzymes; D009153:Mutagens; D011993:Recombinant Fusion Proteins; D003577:Cytochrome P-450 Enzyme System; D001616:beta-Galactosidase