[The ultrastructural characteristics of different histological types of bronchiolar-alveolar cancer].
Morphological study of bronchioloalveolar carcinoma (BAC) was performed by light or electron microscopy in 100 and 33 patients, respectively. BAC-1, 2 and 3 histologic subtypes were established basing on ultrastructural peculiarities which betrayed different cytogenetic origins. Electron microscopic signs of goblet cells were found in cells constituting BAC-1 tumors. BAC-2 tumor cells exhibited ultrastructural characteristics of Clara cells and/or type-II pneumocytes. BAC-3 tumors appeared less differentiated and contained mainly undifferentiated cells and cell clusters displaying various combinations of electron microscopic markers of goblet and Clara cells and type-II pneumocytes.
Smirnova
E A
EA
Grinberg
L M
LM
D002282:Adenocarcinoma, Bronchiolo-Alveolar / Q000145:classification / Q000648:ultrastructure*; D000293:Adolescent; D000328:Adult; D000368:Aged; D001980:Bronchi / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000145:classification / Q000648:ultrastructure*; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D011650:Pulmonary Alveoli / Q000648:ultrastructure
Ul'trastrukturnye osobennosti razlichnykh gistologicheskikh tipov bronkhiolo-al'veoliarnogo raka.