Fv-1 restriction of endogenous feline C-type RD114 virus genome phenotypically mixed with ecotropic murine leukemia viruses.
Endogenous feline leukemia RD114 virus genome rendered capable of infecting mouse cells by phenotypic mixing with an ecotropic murine leukemia virus (MuLV) exhibited the Fv-1 restriction pattern of the ecotropic murine virus. However, RD114 genomes phenotypically mixed with ecotropic MuLV showed one-hit dose-response kinetics, even when titrated with murine cells with the restricted Fv-1 phenotype.
Kakimi
K
K
Department of Viral Oncology, Kyoto University.
Kishida
Y
Y
Higuchi
I
I
Kiyomasu
T
T
Sakai
H
H
Shibata
R
R
Yanagawa
S
S
Adachi
A
A
Ishimoto
A
A
D000406:AKR murine leukemia virus / Q000235:genetics / Q000502:physiology*; D000818:Animals; D002478:Cells, Cultured; D005814:Genes, Viral / Q000235:genetics / Q000502:physiology*; D005256:Leukemia Virus, Feline / Q000235:genetics / Q000472:pathogenicity / Q000502:physiology*; D009052:Leukemia Virus, Murine / Q000502:physiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008907:Mink; D010641:Phenotype; D014773:Virology / Q000379:methods; D014779:Virus Replication / Q000235:genetics / Q000502:physiology*