title: Comparison of computed tomography and magnetic resonance imaging in the evaluation of focal hepatic lesions.
abstract: Two combined magnetic resonance (MR) spin-echo pulse sequences at 0.35 T were compared with dynamic bolus contrast-enhanced computed tomography (CT) in the evaluation of focal hepatic lesions. Each combined MR sequence was performed in a separate group of patients. The first group consisted of 76 patients in whom a moderately T1-weighted sequence (spin echo [SE] 500/30 [repetition time/echo time]) was combined with a T2-weighted sequence (SE 2000/60). In the second group, consisting of 68 patients, a more heavily T1-weighted sequence (SE 250/15) was combined with the T2-weighted sequence. All studies were evaluated in a retrospective blinded fashion, with construction of receiver operating characteristic curves. We conclude that, in detection of patients with one or more focal hepatic lesions, either combined MR sequence was comparable to CT. In the detection of individual hepatic lesions, the sensitivity of the combined MR sequence with a moderately T1-weighted sequence (SE 500/30 and 2000/60) was essentially equivalent to CT (79 vs 77%, respectively). Additionally, a combined MR sequence with a heavily T1-weighted pulse sequence (SE 250/15 and 2000/60) was not statistically different than CT (86 vs 80%, respectively). These findings were supported by the receiver operating characteristic analysis.
authors.affiliation: Department of Radiology, University of California, San Francisco 94131.
authors.forename: J A
authors.initials: JA
authors.lastname: Barakos
authors.forename: H I
authors.initials: HI
authors.lastname: Goldberg
authors.forename: J J
authors.initials: JJ
authors.lastname: Brown
authors.forename: T J
authors.initials: TJ
authors.lastname: Gilbert
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012372:ROC Curve; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed