[The effect of nembutal on the cellular pulse trains of embryonic nerve tissue transplanted into the brain of the rat].
Under nembutal anaesthesia the mean frequency of single unit discharges recorded from allografts of the rat brain was four times lower than the one measured in unanaesthetized animals. A diminished variability was revealed of firing rates and discharge patterns of the cells within grafts in anaesthetized rat brain. In comparison to unanaesthetized animals the number of graft units reacting to a tactile stimulation of contralateral hindlimb of the operated animals was twice lower. Nembutal anaesthesia provoked a full blockade of reactions to the tactile stimuli applied to the ipsilateral side of the animal body.
Senatorov
V V
VV
Obukhova
G P
GP
Silakov
V L
VL
D000818:Animals; D004622:Embryo, Mammalian; D005071:Evoked Potentials / Q000187:drug effects / Q000502:physiology; D008297:Male; D008839:Microelectrodes; D009417:Nerve Tissue / Q000187:drug effects* / Q000502:physiology / Q000637:transplantation; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D010424:Pentobarbital / Q000494:pharmacology*; D010812:Physical Stimulation; D051381:Rats; D011919:Rats, Inbred Strains; D013003:Somatosensory Cortex / Q000187:drug effects* / Q000502:physiology; D014184:Transplantation, Homologous
D010424:Pentobarbital
Vliianie nembutala na impul'satsiiu kletok émbrional'noĭ nervnoĭ tkani, transplantirovannoĭ v mozg krysy.