title: Immunoblot analysis of the humoral immune response to cytomegalovirus in non-pregnant and pregnant guinea pigs.
abstract: The temporal appearance of antibodies to guinea pig cytomegalovirus (CMV) proteins was examined in pregnant and non-pregnant guinea pigs by immunoblotting. Antibodies to 12 guinea pig CMV proteins appeared in a defined time course during primary infection and were detected at a later time and in lower concentrations in pregnant than in non-pregnant guinea pigs.
authors.affiliation: Department of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut.
authors.forename: F R
authors.initials: FR
authors.lastname: Bu
authors.forename: B P
authors.initials: BP
authors.lastname: Griffith
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis* / Q000276:immunology; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000276:immunology*; D005260:Female; D006168:Guinea Pigs; D015151:Immunoblotting; D007700:Kinetics; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology*; D015678:Viral Structural Proteins / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D015678:Viral Structural Proteins