[Prevalence of polyneuropathies in patients with chronic obstructive lung disease].
A multicentric study of 151 COLD patients confirmed the increased prevalence of peripheral polyneuropathies (PNP) in hypoxaemic patients with chronic obstructive lung disease (COLD). 43 (28%) of these 151 COLD patients showed a clinically manifest PNP, whereas in a comparative group of 32 asthmatics there were only 2 clinical PNP cases. Patients with known risk factors for PNP were not included in the study. The polyneuropathy observed in such patients is usually mild, mainly sensorial, distal and leg-accentuated. Of 52 COLD patients with a PaO2 up to 55 Torr, polyneuropathy was seen in 21 (40%), and of 59 COLD patients with a PaO2 above 60 Torr, 10 (17%) had polyneuropathy. In multifactorial genesis (as would be expected), the degree of severity of hypoxaemia (calculated as reduction of the actual PaO2 value below the age-adjusted nominal value), as well as the age of the patient, are statistically significant predictors of clinically manifest PNP.
Kiessling
D
D
Abt. Pneumologie, Medizinische Hochschule, Hannover.
Langenbahn
H
H
Fabel
H
H
Magnussen
H
H
Nolte
D
D
Overlack
A
A
Ulmer
W T
WT
Worth
H
H
D000368:Aged; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010525:Peripheral Nerves / Q000503:physiopathology; D010523:Peripheral Nervous System Diseases / Q000209:etiology*; D012677:Sensation / Q000502:physiology
Untersuchungen zur Polyneuropathieprävalenz bei COLD-Patienten.