Treatment planning of template-guided stereotaxic brain implants.
We have initiated a Phase I clinical trial of interstitial hyperthermia induced with inductively heated ferromagnetic implants in combination with Ir-192 implants for glioblastomas and anaplastic astrocytomas of the brain. For speed and accuracy of the implant procedure, and to control the radiation and thermal dose, a stereotaxic frame is used to position a template. We have modified the Brown-Roberts-Wells frame to be used with a variety of templates which we designed. On the morning of the implant procedure, a CT scan is done, and a CT-based treatment plan is then completed before the patient goes to the operating room. We also describe the CT-based treatment planning system developed to accommodate the template-guided implant and illustrate its clinical use.
Lulu
B A
BA
Department of Radiation Oncology, University of Arizona, Tucson 85724.
Lutz
W
W
Stea
B
B
Cetas
T C
TC
D001918:Brachytherapy / Q000295:instrumentation*; D001932:Brain Neoplasms / Q000532:radiotherapy / Q000628:therapy*; D003131:Combined Modality Therapy; D006801:Humans; D006979:Hyperthermia, Induced / Q000295:instrumentation*; D019736:Prostheses and Implants; D013238:Stereotaxic Techniques / Q000295:instrumentation*