title: Feline immunodeficiency virus: prevalence, disease associations and isolation.
abstract: Of 467 cat serums tested for antibody to feline immunodeficiency virus (FIV) 120 (26%) were positive. The average age of positive cats was 7.5 years (range 1 to 16 years), and 67% were male. Of 110 serums collected in 1980, 27 (24.5%) were positive. A wide variety of clinical signs including oral cavity disease, anorexia, weight loss, lethargy, depression, fever, respiratory and urinary tract disease, conjunctivitis, abscesses, anaemia and lymphadenopathy were observed in the cats with serum antibody. There was often a history of chronic disease or recurrence of particular or various clinical signs in these cats. FIV was isolated from 4 of 8 FIV antibody positive cats by cocultivation of patient lymphocytes with donor lymphocytes in the presence of interleukin 2.
authors.affiliation: Central Veterinary Diagnostic Laboratory, Victoria.
authors.forename: S C
authors.initials: SC
authors.lastname: Friend
authors.forename: C J
authors.initials: CJ
authors.lastname: Birch
authors.forename: P M
authors.initials: PM
authors.lastname: Lording
authors.forename: J A
authors.initials: JA
authors.lastname: Marshall
authors.forename: M J
authors.initials: MJ
authors.lastname: Studdert
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D002371:Cat Diseases / Q000453:epidemiology*; D002415:Cats; D002478:Cells, Cultured; D005260:Female; D007153:Immunologic Deficiency Syndromes / Q000150:complications / Q000453:epidemiology / Q000662:veterinary*; D008214:Lymphocytes / Q000382:microbiology; D008297:Male; D009919:Orchiectomy / Q000662:veterinary; D015995:Prevalence; D012190:Retroviridae / Q000276:immunology / Q000302:isolation & purification* / Q000648:ultrastructure; D012192:Retroviridae Infections / Q000150:complications / Q000453:epidemiology / Q000662:veterinary*; D012737:Sex Factors; D013047:Specific Pathogen-Free Organisms
chemical_list: D000914:Antibodies, Viral