title: Phase I clinical studies with cytotoxic drugs: pharmacokinetic and pharmacodynamic considerations.
authors.affiliation: University of Newcastle upon Tyne, Division of Oncology, Medical School, UK.
authors.forename: D R
authors.initials: DR
authors.lastname: Newell
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000494:pharmacology; D004341:Drug Evaluation; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D008722:Methods; D051379:Mice
chemical_list: D000970:Antineoplastic Agents