title: Growth hormone gene regulation: a paradigm for cell-type-specific gene activation.
abstract: The growth hormone (GH) gene is specifically expressed within specialized cells of the anterior pituitary. The central role in GH gene activation is played by GHF-1, a homeodomain protein that is itself specifically expressed in the anterior pituitary.
authors.affiliation: Department of Pharmacology, School of Medicine, University of California, San Diego, La Jolla 92093.
authors.forename: M
authors.initials: M
authors.lastname: Karin
authors.forename: J L
authors.initials: JL
authors.lastname: Castrillo
authors.forename: L E
authors.initials: LE
authors.lastname: Theill
mesh_terms: D000818:Animals; D005786:Gene Expression Regulation; D013006:Growth Hormone / Q000235:genetics*; D008322:Mammals; D008957:Models, Genetic; D010903:Pituitary Gland, Anterior / Q000196:embryology; D015533:Transcriptional Activation
chemical_list: D013006:Growth Hormone