[HIV1 seropositivity and B and D viruses in West Africa].
This study was undertaken to investigate relationships between three widespread viruses in West Africa, i.e. HIV1 and viruses B and D, in Ivory Coast. Serologic tests for viruses B and D were carried out in a random sample of black adults of both sexes with asymptomatic HIV1 seropositivity. Coinfection by virus B or viruses B and D was a common finding. Coinfection with both viruses B and D, but not with virus B alone, was found to be significantly more frequent in these HIV1-infected adults than in a control group with acute viral hepatitis. Potential interactions between the HIV1 and viruses B and D as well as other viruses are discussed. These findings suggest that one or several cofactors acting alone or in combination play a major role in the clinical expression of HIV infection. The results of this study, together with the suggestion put forward by several investigators that B virus infection may increase the severity of AIDS, are evidence in support of the value of immunization against the B virus in the management of AIDS.
Soubeyrand
J
J
Faculté de Médecine, Service 3e Cycle, Marseille, France.
Niamkey
E K
EK
Ouattara
S A
SA
Diallo
D
D
Leleu
J P
JP
Beda
B Y
BY
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D007560:Cote d'Ivoire; D005260:Female; D006679:HIV Seropositivity / Q000150:complications* / Q000453:epidemiology; D015497:HIV-1; D006509:Hepatitis B / Q000150:complications* / Q000453:epidemiology; D003699:Hepatitis D / Q000150:complications* / Q000453:epidemiology; D006801:Humans; D008297:Male; D015995:Prevalence; D011446:Prospective Studies
Séropositivité VIH1, virus B et D en Afrique de l'Ouest.