[Experience with the treatment of diabetic coma].
To investigate the effect of low-dose versus high-dose insulin treatment of Kussmaul's coma, the authors treated 2 groups of relevant patients. Group I treated with low-dose insulin in combination with other therapeutic measures achieved a progressive decrease of glycemia within 8 hours. Complications were not registered. Group II on high-dose insulin scheme exhibited a drop in blood sugar resultant in hypoglycemia in 4, hypotonia in 2, brain edema in 1 patient. The absence of complications, availability and simplicity support the advantages of the low-dose regime which is now widely introduced into clinical practice.
Khazipova
L G
LG
Akhmetova
B Kh
BKh
D000293:Adolescent; D000328:Adult; D000368:Aged; D001639:Bicarbonates / Q000008:administration & dosage*; D003926:Diabetic Coma / Q000097:blood / Q000188:drug therapy*; D016883:Diabetic Ketoacidosis / Q000097:blood / Q000150:complications*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000188:drug therapy*; D007003:Hypoglycemia / Q000517:prevention & control; D007262:Infusions, Intravenous; D007273:Injections, Intramuscular; D007328:Insulin / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D012964:Sodium / Q000008:administration & dosage*; D017693:Sodium Bicarbonate
D001639:Bicarbonates; D007328:Insulin; D017693:Sodium Bicarbonate; D012964:Sodium
Opyt lecheniia diabeticheskoĭ komy.