Occupational risk of human parvovirus B19 infection for school and day-care personnel during an outbreak of erythema infectiosum.
Human parvovirus B19, the cause of erythema infectiosum, has recently been associated with adverse fetal outcomes. During a large outbreak of erythema infectiosum in Connecticut, a survey was conducted on 571 (90%) of 634 school and day-care personnel to determine the risk of acquiring B19 infection. Serologic evidence of B19 infection was determined by using an enzyme-linked immunosorbent assay. Of the school and day-care personnel, 58% had evidence of previous B19 infection. The minimal rate of B19 infection in susceptible personnel during the outbreak was 19%. The risk was increased for teachers and day-care providers who had contact with younger children and with greater numbers of ill children. These results suggest that B19 infection is an occupational risk for school and day-care personnel.
Gillespie
S M
SM
Division of Viral Diseases, Centers for Disease Control, Atlanta, Ga.
Cartter
M L
ML
Asch
S
S
Rokos
J B
JB
Gary
G W
GW
Tsou
C J
CJ
Hall
D B
DB
Anderson
L J
LJ
Hurwitz
E S
ES
D000328:Adult; D002648:Child; D002656:Child Day Care Centers; D003237:Connecticut / Q000453:epidemiology; D004196:Disease Outbreaks; D004890:Erythema / Q000453:epidemiology / Q000209:etiology* / Q000276:immunology; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D009784:Occupational Diseases / Q000209:etiology* / Q000276:immunology; D010322:Parvoviridae Infections / Q000453:epidemiology / Q000209:etiology* / Q000276:immunology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000209:etiology / Q000276:immunology; D011256:Pregnancy Outcome; D011446:Prospective Studies; D012307:Risk Factors; D012574:Schools
D007074:Immunoglobulin G; D007075:Immunoglobulin M