title: New foldback transposable element TFB1 found in histone genes of the midge Chironomus thummi.
abstract: A new Foldback transposable element (TFB1) has been found in the histone H1-H3 intergenic region in the midge Chironomus thummi thummi. TFB1 has long terminal inverted repeats, composed of short, degenerate subrepeats and is flanked by nine or ten base-pair "target site" duplications. TFB1 is present in at least two adjacent histone gene units in Ch. th. thummi, indicating a homogenization of histone gene repeats. The copy number and chromosomal distribution of TFB1 are different in the closely related subspecies Ch. th. thummi and Ch. th. piger. showing that amplification, elimination and transposition of TFB1 have occurred recently during evolution.
authors.affiliation: Institut für Genetik, Ruhr-Universität, Bochum, F.R.G.
authors.forename: T
authors.initials: T
authors.lastname: Hankeln
authors.forename: E R
authors.initials: ER
authors.lastname: Schmidt
mesh_terms: D000818:Animals; D001483:Base Sequence; D005075:Biological Evolution; D002683:Chironomidae / Q000235:genetics*; D004251:DNA Transposable Elements; D005784:Gene Amplification; D006657:Histones / Q000235:genetics*; D008969:Molecular Sequence Data; D009154:Mutation; D012091:Repetitive Sequences, Nucleic Acid; D015183:Restriction Mapping
chemical_list: D004251:DNA Transposable Elements; D006657:Histones