title: [The combined therapy of patients with severe craniocerebral injury].
abstract: The hemostasis system was studied in 423 patients. Coagulation occurred in a definite sequence: its expressiveness and duration were determined by the severity and form of brain damage. In the period of hypercoagulative changes (from 2 to 15 days and longer), thrombotic processes were revealed in 16% of the cases. Anticoagulative treatment including heparin, indirect anticoagulants, des- and antiaggregates, as well as fibrinolytics were applied in 27% of the cases, which reduced mortality by 12%.
authors.forename: M R
authors.initials: MR
authors.lastname: Gadzhiev
mesh_terms: D000208:Acute Disease; D000925:Anticoagulants / Q000008:administration & dosage; D001778:Blood Coagulation Disorders / Q000097:blood / Q000188:drug therapy / Q000209:etiology; D001930:Brain Injuries / Q000097:blood / Q000150:complications / Q000628:therapy*; D003131:Combined Modality Therapy; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000188:drug therapy / Q000209:etiology; D004359:Drug Therapy, Combination; D006801:Humans; D009104:Multiple Trauma / Q000097:blood / Q000150:complications / Q000628:therapy; D013997:Time Factors
chemical_list: D000925:Anticoagulants
vernacular_title: Kompleksnaia terapiia bol'nykh s tiazheloĭ cherepno-mozgovoĭ travmoĭ.