[Encephalo-myelo-radiculitis with high HSV-1 antibody index of CSF].
A rare case of encephalo-myelo- radiculitis with high herpes simplex virus type 1 (HSV-1) antibody index of CSF was reported. The case was a 43-year-old male. Double vision, cerebellar ataxia, Th4-12 truncal segmental total sensory disturbance and urinary retention were found, but those symptoms disappeared after 3 weeks of administration of acyclovir and prednisolone. Because the HSV-1 antibody index of the CSF increased significantly, the patient's disease was summarised to have been due to HSV-1, T1-intensified MRI revealed a low-intensity area in the Th5-8 region which coincided with the lesion causing the neurological symptoms, while T2-intensified MRI revealed scattered high intensity area in the cerebral hemisphere. MRI was thus useful for confirming the lesions.
Endoh
J
J
Department of Internal Medicine, Takamatsu Red Cross Hospital.
Ogasawara
N
N
Yamamoto
M
M
D000212:Acyclovir / Q000008:administration & dosage; D000328:Adult; D000914:Antibodies, Viral / Q000134:cerebrospinal fluid*; D004679:Encephalomyelitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D006561:Herpes Simplex; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011239:Prednisolone / Q000008:administration & dosage; D011843:Radiculopathy / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D018139:Simplexvirus / Q000276:immunology*
D000914:Antibodies, Viral; D011239:Prednisolone; D000212:Acyclovir