title: A nosocomial outbreak of epidemic keratoconjunctivitis due to adenovirus type 37.
abstract: An outbreak of epidemic keratoconjunctivitis occurred at the department of ophthalmology of a hospital in Yokohama, involving 14 inpatients, 12 outpatients, and 2 doctors. Adenovirus type 37 (Ad-37) was isolated from the conjunctival swab in 12 of 18 cases. In neutralization tests, the isolates showed some cross-reaction with adenovirus type 19 (Ad-19). The Ad-37 isolates were indistinguishable from each other and from the prototype Ad-37, but distinct from the prototype Ad-19 in the restriction endonuclease analysis of viral DNA.
authors.affiliation: Division of Microbiology, Yokohama City Institute of Health, Kanagawa.
authors.forename: R
authors.initials: R
authors.lastname: Takeuchi
authors.forename: Y
authors.initials: Y
authors.lastname: Nomura
authors.forename: M
authors.initials: M
authors.lastname: Kojima
authors.forename: E
authors.initials: E
authors.lastname: Uchio
authors.forename: N
authors.initials: N
authors.lastname: Kobayashi
authors.forename: M
authors.initials: M
authors.lastname: Matumoto
mesh_terms: D000258:Adenovirus Infections, Human / Q000453:epidemiology*; D000260:Adenoviruses, Human / Q000235:genetics / Q000302:isolation & purification; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003228:Conjunctiva / Q000382:microbiology; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology; D004262:DNA Restriction Enzymes; D004279:DNA, Viral / Q000378:metabolism; D015828:Eye Infections, Viral / Q000453:epidemiology* / Q000382:microbiology; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D016130:Immunophenotyping; D007564:Japan / Q000453:epidemiology; D007637:Keratoconjunctivitis / Q000453:epidemiology* / Q000382:microbiology; D008875:Middle Aged; D009500:Neutralization Tests
chemical_list: D004279:DNA, Viral; D004262:DNA Restriction Enzymes