[A kinetic analysis of the action of a synaptosomal factor on Na, K-ATPase].
A synaptosomal factor stimulated by neurotransmitters activates the Na, K-ATPase system effecting the phosphorylating intermediates moving the Na, K-ATPase system in the mode of simultaneous transport of Na+ and K+. This conclusion has been made during the analysis of kinetics of the effect of MgATP complex, free Mg2+ ions and ATP on Na, K-ATPase activity. Unlike the EGTA, the factor under study does not change the number of essential activators (ions of Na+ and K+) of the Na, K-ATPase system at the equimolar ATP and Mg2+ correlation.
Kometiani
Z P
ZP
Tsakadze
L G
LG
D004305:Dose-Response Relationship, Drug; D004789:Enzyme Activation / Q000187:drug effects; D066298:In Vitro Techniques; D008433:Mathematics; D009638:Norepinephrine / Q000494:pharmacology; D000254:Sodium-Potassium-Exchanging ATPase / Q000493:pharmacokinetics*; D013574:Synaptosomes / Q000187:drug effects / Q000502:physiology*
D000254:Sodium-Potassium-Exchanging ATPase; D009638:Norepinephrine
Kineticheskiĭ analiz deĭstviia sinaptosomal'nogo faktora na Na, K-ATFazu.