The two oxygen-regulated subunits of cytochrome c oxidase in Dictyostelium discoideum derive from a common ancestor.
The two smallest polypeptide components of D. discoideum cytochrome c oxidase, whose alternative expression depends on oxygen concentration [Schiavo, G. and Bisson, R. (1989) J. Biol. Chem. 264, 7129-7134], have been partially sequenced. They show 45% homology and are isoforms of the same subunit, which must be encoded on two different genes.
Capaldi
R A
RA
Institute of Molecular Biology, University of Oregon, Eugene 97403.
Zhang
Y Z
YZ
Rizzuto
R
R
Sandonà
D
D
Schiavo
G
G
Bisson
R
R
D000595:Amino Acid Sequence; D004023:Dictyostelium / Q000201:enzymology*; D003576:Electron Transport Complex IV / Q000235:genetics / Q000378:metabolism; D014644:Genetic Variation; D007527:Isoenzymes / Q000235:genetics / Q000378:metabolism; D008969:Molecular Sequence Data; D010100:Oxygen / Q000494:pharmacology*; D012689:Sequence Homology, Nucleic Acid
D007527:Isoenzymes; D003576:Electron Transport Complex IV; D010100:Oxygen