Topoisomerase inhibitors suppress release of globin sequences into small soluble DNA in erythroblasts.
Strauss
P R
PR
Department of Biology, Northeastern University, Boston, Massachusetts 02115.
D000740:Anemia / Q000473:pathology; D000818:Animals; D002166:Camptothecin / Q000494:pharmacology; D002843:Chromatin / Q000187:drug effects / Q000648:ultrastructure; D004247:DNA / Q000378:metabolism*; D004249:DNA Damage; D004121:Dimethyl Sulfoxide / Q000494:pharmacology; D004357:Drug Synergism; D004900:Erythroblasts / Q000187:drug effects* / Q000378:metabolism; D005796:Genes; D005914:Globins / Q000235:genetics*; D051379:Mice; D013713:Teniposide / Q000494:pharmacology; D059004:Topoisomerase I Inhibitors; D059005:Topoisomerase II Inhibitors; D014158:Transcription, Genetic
D002843:Chromatin; D059004:Topoisomerase I Inhibitors; D059005:Topoisomerase II Inhibitors; D005914:Globins; D004247:DNA; D013713:Teniposide; D002166:Camptothecin; D004121:Dimethyl Sulfoxide