title: Contrast media in sialography: a comparison of Lipiodol Ultra Fluid and Urografin 290.
abstract: A prospective, randomized study of 60 patients undergoing sialography was conducted to compare Lipiodol Ultra Fluid (UF) (Ethyl diiodostearate, May & Baker Ltd), with Urografin 290 (meglumine diatrizoate 52.1% w/v and sodium diatrizoate 7.9% w/v, Schering). The quality of the images, the clinical tolerance and the side-effects of contrast were compared. Both agents produced adequate opacification of ducts but poor intra-gland duct filling was seen in two patients examined with Lipiodol UF. There were significantly more side-effects (which were also more severe) in the Lipiodol group. It is concluded that Urografin 290 is the better contrast agent for sialography because of better filling of intra-gland ducts and greater clinical tolerance.
authors.affiliation: Department of Radiology, University Hospital of South Manchester.
authors.forename: D A
authors.initials: DA
authors.lastname: Nicholson
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003974:Diatrizoate Meglumine / Q000009:adverse effects; D004108:Dilatation, Pathologic / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007459:Iodized Oil / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D010306:Parotid Gland / Q000000981:diagnostic imaging; D011446:Prospective Studies; D011897:Random Allocation; D012466:Salivary Gland Diseases / Q000000981:diagnostic imaging*; D012796:Sialography; D013363:Submandibular Gland / Q000000981:diagnostic imaging; D013649:Taste / Q000187:drug effects
chemical_list: D003974:Diatrizoate Meglumine; D007459:Iodized Oil