title: Detection of respiratory chain dysfunction by measuring lactate and pyruvate production in cultured fibroblasts.
authors.affiliation: Department of Pediatrics, University Hospital of Amsterdam (AMC), The Netherlands.
authors.forename: F A
authors.initials: FA
authors.lastname: Wijburg
authors.forename: N
authors.initials: N
authors.lastname: Feller
authors.forename: W
authors.initials: W
authors.lastname: Ruitenbeek
authors.forename: J M
authors.initials: JM
authors.lastname: Trijbels
authors.forename: R C
authors.initials: RC
authors.lastname: Sengers
authors.forename: H R
authors.initials: HR
authors.lastname: Scholte
authors.forename: H
authors.initials: H
authors.lastname: Przyrembel
authors.forename: R J
authors.initials: RJ
authors.lastname: Wanders
mesh_terms: D000592:Amino Acid Metabolism, Inborn Errors / Q000175:diagnosis*; D002478:Cells, Cultured; D002675:Child, Preschool; D030401:Cytochrome-c Oxidase Deficiency; D005347:Fibroblasts / Q000378:metabolism*; D006801:Humans; D007231:Infant, Newborn; D007773:Lactates / Q000096:biosynthesis*; D019344:Lactic Acid; D008928:Mitochondria / Q000201:enzymology*; D010101:Oxygen Consumption; D011773:Pyruvates / Q000378:metabolism*; D019289:Pyruvic Acid; D011808:Quinone Reductases / Q000172:deficiency
chemical_list: D007773:Lactates; D011773:Pyruvates; D019344:Lactic Acid; D019289:Pyruvic Acid; C041831:NADH dehydrogenase (quinone); D011808:Quinone Reductases