title: Congenital multiple plaquelike glomus tumors.
abstract: We encountered two patients with congenital multiple plaquelike glomus tumors. These lesions were present at birth and enlarged with body growth, attaining a diameter of up to 13 cm. The diagnosis was confirmed by histologic and electron-microscopic examination, which revealed the typical changes of glomus tumors. Immunocytochemistry findings demonstrated the tumor cells to be vimentin- and alpha-smooth muscle-actin-positive and desmin-negative. On ultrastructural examination, typical dense bodies and attachment plaques were easily found within the tumor cells. Glomus cells were coated by a thick basal lamina.
authors.affiliation: Department of Dermatology, Ludwig-Maximilians Universität Munich, West Germany.
authors.forename: M
authors.initials: M
authors.lastname: Landthaler
authors.forename: O
authors.initials: O
authors.lastname: Braun-Falco
authors.forename: F
authors.initials: F
authors.lastname: Eckert
authors.forename: W
authors.initials: W
authors.lastname: Stolz
authors.forename: M
authors.initials: M
authors.lastname: Dorn
authors.forename: H H
authors.initials: HH
authors.lastname: Wolff
mesh_terms: D002648:Child; D005918:Glomus Tumor / Q000032:analysis / Q000151:congenital* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D007381:Intermediate Filament Proteins / Q000032:analysis; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000032:analysis / Q000151:congenital* / Q000473:pathology; D012878:Skin Neoplasms / Q000032:analysis / Q000151:congenital* / Q000473:pathology
chemical_list: D007381:Intermediate Filament Proteins