title: [Results of a serological study of the natural spread of maedi-visna virus infection in a sheep herd during an observation period of 30 months].
abstract: In a sheep population consisting of animals of different breeds the epidemiologic development of the Maedi-Visna-infection was evaluated by means of monthly Immune Diffusion Test (ID) for a period of 30 months. At the beginning the herd consisted of eight animals, where four of them showed clinical symptoms indicative for a MV-infection with positive serological results. The other 4 animals were negative. The herd increased in number by including the offspring and buying in other animals. During the time of 30 months only in one animal a seroconversion could be observed. In nine of 13 lambs borne of seropositive mothers colostral antibodies could be observed. By testing the colostrum of MV-seropositive mothers 6 of 7 animals showed precipitating antibodies. Positive sera showed average titers of 1:2 till 1:64, the highest titer was 1:512. On the postmortal examination of five serological positive animals which were killed because of dominant clinical symptoms, three of them showed MV-lesions partly superinfected with bacteria. In one sheep the diagnosis was pasteurellosis. On a further animal the clinical picture and the histologic results were indicative for the Visna-form of the disease.
authors.affiliation: Bundesanstalt für Virusseuchenbekämpfung bei Haustieren Wien-Hetzendorf.
authors.forename: B
authors.initials: B
authors.lastname: Leitold
authors.forename: W
authors.initials: W
authors.lastname: Schuller
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D004196:Disease Outbreaks / Q000662:veterinary*; D005779:Immunodiffusion; D011021:Pneumonia, Progressive Interstitial, of Sheep / Q000635:transmission*; D012756:Sheep; D014790:Visna-maedi virus / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral
vernacular_title: Ergebnisse einer serologischen Studie über die natürliche Ausbreitung der Maedi-Visna-Virusinfektion in einer Schafherde während eines Beobachtungszeitraumes von 30 Monaten.