[Ultrastructural papilloma virus detection in precancerous and early stages of cervix cancer].
100 women with pathologic findings in the uterine cervix are the basis of this study. To assess papilloma virus articles methods of electron microscopy have been used in specimens of 59 women if koilocytes were present. Inside the nucleus of koilocytes in 51 cases virus particles could be detected, in 31 cases isolated and in 20 cases agglomerated between the chromatin. In all 10 condylomas without nuclear atypia we could assess virus particles. With increasing atypia the detection of papilloma virus decreases.
Barten
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Klinik für Gynäkologie und Geburtshilfe, Bereichs Medizin der Wilhelm-Pieck-Universität Rostock.
D001706:Biopsy; D002584:Cervix Uteri / Q000473:pathology; D003218:Condylomata Acuminata / Q000473:pathology*; D004848:Epithelium / Q000473:pathology; D005260:Female; D006801:Humans; D007181:Inclusion Bodies, Viral / Q000648:ultrastructure*; D008854:Microscopy, Electron; D009367:Neoplasm Staging; D027383:Papillomaviridae / Q000648:ultrastructure*; D011230:Precancerous Conditions / Q000473:pathology*; D014412:Tumor Virus Infections / Q000473:pathology*; D002583:Uterine Cervical Neoplasms / Q000473:pathology*; D014626:Vaginal Smears
Ultrastruktureller Papillomvirusnachweis bei Vor- und Frühstadien des Zervixkarzinoms.