[The accumulation of lipid peroxidation products in the eye structures of mice under whole-body x-ray irradiation].
In studying the effect of whole-body X-irradiation on the accumulation of lipid peroxidation products (conjugated dienes, TBA-active products, and Schiff bases) in retina and retinal pigmented epithelium of pigmented and nonpigmented mice it was shown that irradiation of dark-pigmented mice does not cause even a slight accumulation of lipid peroxidation products as compared to that in the controls. Albino mice exhibited a marked increase in the level of lipid peroxidation products which was manifested soon after irradiation and persisted for at least 3 months after irradiation. Melanine is suggested to participate in protecting eye structures against pro-oxidizing action of ionizing radiation.
Sakina
N L
NL
Dontsov
A E
AE
Afanas'ev
G G
GG
Ostrovski
M A
MA
Pelevina
I I
II
D000818:Animals; D004307:Dose-Response Relationship, Radiation; D005123:Eye / Q000378:metabolism / Q000528:radiation effects*; D005609:Free Radicals; D015227:Lipid Peroxidation / Q000528:radiation effects*; D008543:Melanins / Q000378:metabolism / Q000528:radiation effects; D051379:Mice; D008810:Mice, Inbred C57BL; D010857:Pigment Epithelium of Eye / Q000378:metabolism / Q000528:radiation effects; D012160:Retina / Q000378:metabolism / Q000528:radiation effects; D013997:Time Factors; D014916:Whole-Body Irradiation
D005609:Free Radicals; D008543:Melanins
Akkumuliatsiia produktov perekisnogo okisleniia lipidov v strukturakh glaza mysheĭ pri obshchem rentgenovskom obluchenii.