title: Effect of sodium bicarbonate on racing Standardbreds.
abstract: Twenty-two Standardbred horses in race training were used in a crossover experiment to determine the effect of oral sodium bicarbonate (NaHCO3) administration on performance and metabolic responses to a 1.6-km (1-mile) race. Horses were paired and one horse in each pair was treated with either NaHCO3 (300 mg/kg BW) or a placebo, 2.5 h before they raced against each other. Each horse was scheduled to compete in two races, approximately 1 wk apart, one on each treatment. Horses always raced in the same pairs. Fourteen horses successfully completed both races. Jugular blood samples were obtained 1.5 h after treatment (rest), immediately before racing, 5 min post-race and 15 min post-race. In six horses, blood samples also were obtained 30 min post-race. Race times averaged 1.1 s faster after NaHCO3 treatment (P less than .1). Sodium bicarbonate treatment also elevated blood pH (P less than .05). In the horses sampled 15 and 30 min post-race, blood lactate disappearance was faster with the NaHCO3 treatment (P less than .05). The NaHCO3 may delay the fatigue precipitated by i.m. acidosis. Because other factors may limit performance (musculoskeletal soundness, cardiovascular and respiratory ability), NaHCO3 would not be expected to enhance the performance of all horses. However, the effect of NaHCO3 on lactate clearance may have implications for all intensively worked horses; because lactate and the associated hydrogen ions are believed to cause muscle damage and soreness, any mechanism to increase their removal rate could benefit the equine athlete.
authors.affiliation: Dept. of Anim Sci., University of Illinois, Urbana 61801.
authors.forename: L
authors.initials: L
authors.lastname: Lawrence
authors.forename: K
authors.initials: K
authors.lastname: Kline
authors.forename: P
authors.initials: P
authors.lastname: Miller-Graber
authors.forename: A
authors.initials: A
authors.lastname: Siegel
authors.forename: E
authors.initials: E
authors.lastname: Kurcz
authors.forename: M
authors.initials: M
authors.lastname: Fisher
authors.forename: K
authors.initials: K
authors.lastname: Bump
mesh_terms: D000136:Acid-Base Equilibrium / Q000187:drug effects; D000818:Animals; D001639:Bicarbonates / Q000494:pharmacology*; D006736:Horses / Q000097:blood / Q000378:metabolism / Q000502:physiology*; D006863:Hydrogen-Ion Concentration; D007773:Lactates / Q000097:blood; D005082:Physical Exertion / Q000187:drug effects*; D011897:Random Allocation; D012964:Sodium / Q000494:pharmacology*; D017693:Sodium Bicarbonate
chemical_list: D001639:Bicarbonates; D007773:Lactates; D017693:Sodium Bicarbonate; D012964:Sodium