[The determination of the level of antibodies to Epstein-Barr virus antigens in organizing groups at high risk for lung cancer disease].
Titers of antibodies against Epstein-Barr virus (EBV) antigen were measured in 450 subjects aged 40 years and older. The group included patients with lung cancer, cases of non-specific chronic lung pathology and healthy subjects (150 persons in each subset). A significant increase in the level of antibodies to capsid EBV antigen was established in patients with lung cancer and chronic non-specific lung pathology as compared to healthy controls. Parameters of specific immunologic response to Epstein-Barr virus may be recommended as additional criteria for inclusion into the group at risk for lung cancer.
Zyrianov
B N
BN
Podoplekin
V D
VD
Siianov
V S
VS
Kuznetsova
T I
TI
Tuzikov
S A
SA
D000230:Adenocarcinoma / Q000453:epidemiology* / Q000276:immunology; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D000918:Antibody Specificity / Q000276:immunology; D000956:Antigens, Viral / Q000276:immunology*; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology* / Q000276:immunology; D005455:Fluorescent Antibody Technique; D004854:Herpesvirus 4, Human / Q000276:immunology*; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000032:analysis; D008173:Lung Diseases, Obstructive / Q000276:immunology; D008175:Lung Neoplasms / Q000453:epidemiology* / Q000276:immunology; D012307:Risk Factors; D016036:Seroepidemiologic Studies
D000914:Antibodies, Viral; D000956:Antigens, Viral; D007070:Immunoglobulin A; D007074:Immunoglobulin G
Opredelenie urovnia antitel k antigenam virusa Epstaĭna--Bar pri formirovanii grupp povyshennogo riska zabolevaniia rakom legkogo.