title: Perineal leiomyosarcoma.
abstract: Perineal leiomyosarcomas are rare aggressive tumors for which the therapy remains to be defined. These tumors may be extensively infiltrating and therapy may require radical surgery. The problems encountered in treating these tumors are similar to those for retroperitoneal sarcomas. Namely, delay in diagnosis, lack of distinct anatomic boundaries, and close proximity to and encroachment on multiple organs prevents resection with adequate surgical margins. We discuss the current literature and present our management of perineal leiomyosarcomas.
authors.affiliation: Department of General Surgery, National Naval Medical Center, Bethesda, Maryland.
authors.forename: J P
authors.initials: JP
authors.lastname: Rice
authors.forename: D C
authors.initials: DC
authors.lastname: MacGillivray
authors.forename: R W
authors.initials: RW
authors.lastname: Sharpe
authors.forename: E B
authors.initials: EB
authors.lastname: Weiser
authors.forename: B C
authors.initials: BC
authors.lastname: Ghosh
mesh_terms: D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000175:diagnosis / Q000628:therapy*; D008875:Middle Aged; D010502:Perineum; D014057:Tomography, X-Ray Computed