The bivalent ligand approach in the design of highly selective opioid receptor antagonists.
Portoghese
P S
PS
Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota, Minneapolis 55455.
D015195:Drug Design; D006801:Humans; D007536:Isomerism; D008024:Ligands; D009292:Narcotic Antagonists / Q000494:pharmacology*; D011957:Receptors, Opioid / Q000187:drug effects*; D013329:Structure-Activity Relationship
D008024:Ligands; D009292:Narcotic Antagonists; D011957:Receptors, Opioid