title: Search for the functional substrate proteins of protein kinases and their selective inhibitors.
authors.affiliation: Department of Pharmacology, Nagoya University School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Hidaka
authors.forename: M
authors.initials: M
authors.lastname: Watanabe
authors.forename: H
authors.initials: H
authors.lastname: Tokumitsu
mesh_terms: D019307:1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine / Q000031:analogs & derivatives*; D000310:Adrenal Gland Neoplasms / Q000473:pathology; D000818:Animals; D002118:Calcium / Q000378:metabolism; D017871:Calcium-Calmodulin-Dependent Protein Kinases; D002148:Calmodulin-Binding Proteins / Q000302:isolation & purification* / Q000378:metabolism; D002454:Cell Differentiation / Q000187:drug effects; D007546:Isoquinolines / Q000494:pharmacology*; D009363:Neoplasm Proteins / Q000378:metabolism; D010673:Pheochromocytoma / Q000473:pathology; D010766:Phosphorylation; D010879:Piperazines / Q000494:pharmacology*; D011485:Protein Binding; D047428:Protein Kinase Inhibitors; D011494:Protein Kinases / Q000378:metabolism / Q000502:physiology*; D011499:Protein Processing, Post-Translational; D051381:Rats; D015290:Second Messenger Systems / Q000187:drug effects; D013379:Substrate Specificity; D013449:Sulfonamides; D014407:Tumor Cells, Cultured
chemical_list: D002148:Calmodulin-Binding Proteins; D007546:Isoquinolines; D009363:Neoplasm Proteins; D010879:Piperazines; D047428:Protein Kinase Inhibitors; D013449:Sulfonamides; C063302:KN 62; D019307:1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; D011494:Protein Kinases; D017871:Calcium-Calmodulin-Dependent Protein Kinases; C063509:N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide; D002118:Calcium