title: [An advanced gastric cancer with varied histopathologic features including a choriocarcinoma: report of a case].
abstract: A 77-year-old male, complaining of epigastralgia, was admitted to hospital. An upper GI series revealed a hemispheric filling defect at the greater curvature of the lower gastric body and two submucosal tumor-like lesions of the antrum. Closer inspection revealed a tumor measuring 60 x 42 mm, with an irregular ulcer, and two submucosal tumor-like lesions with bridging folds, measuring 42 x 28 mm and 20 x 14 mm, respectively. Histologically, the microscopic features in the ulcerated tumor showed a variety of tumor cells with clear PAS-positive cytoplasms and marked atypical nuclei forming glandular structures that predominated. Additionally, a clear cell carcinoma, a papillary adenocarcinoma, a signet-ring cell carcinoma, and a choriocarcinoma were partially seen. Finally, in the submucosal tumor-like lesions, diffuse small tumor cells with scanty PAS-positive cytoplasms without granular structures were seen.
authors.affiliation: 1st Dept. of Int. Med. School of Med., Iwate Medical Univ.
authors.forename: S
authors.initials: S
authors.lastname: Orii
authors.forename: S
authors.initials: S
authors.lastname: Chiba
authors.forename: K
authors.initials: K
authors.lastname: Isogai
authors.forename: O
authors.initials: O
authors.lastname: Nakano
authors.forename: A
authors.initials: A
authors.lastname: Kano
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology; D002288:Adenocarcinoma, Mucinous / Q000473:pathology; D000231:Adenocarcinoma, Papillary / Q000473:pathology; D000368:Aged; D002822:Choriocarcinoma / Q000473:pathology* / Q000601:surgery; D005743:Gastrectomy; D006801:Humans; D008297:Male; D013274:Stomach Neoplasms / Q000473:pathology* / Q000601:surgery