title: Prolonged mu- and delta-receptor occupancy may result in naloxone-reversible respiratory depression and naloxone-irreversible antinociception.
authors.affiliation: Department of Central Diagnostics, Rheinische Landes-Hochschulklinik, University Clinic of Essen, FRG.
authors.forename: E
authors.initials: E
authors.lastname: Freye
authors.forename: G
authors.initials: G
authors.lastname: Schenk
mesh_terms: D015760:Alfentanil / Q000494:pharmacology; D000818:Animals; D003864:Depression, Chemical; D004285:Dogs; D005283:Fentanyl / Q000494:pharmacology; D009270:Naloxone / Q000494:pharmacology; D009619:Nociceptors / Q000187:drug effects / Q000502:physiology*; D011957:Receptors, Opioid / Q000187:drug effects / Q000502:physiology*; D017465:Receptors, Opioid, delta; D017450:Receptors, Opioid, mu; D012119:Respiration / Q000187:drug effects / Q000502:physiology*; D013797:Thebaine / Q000031:analogs & derivatives / Q000494:pharmacology
chemical_list: D011957:Receptors, Opioid; D017465:Receptors, Opioid, delta; D017450:Receptors, Opioid, mu; C063081:RX 140M; D015760:Alfentanil; D013797:Thebaine; D009270:Naloxone; D005283:Fentanyl