Risk factors for invasive carcinoma of the uterine cervix in Latin America.
A study of 759 cervical cancer patients, 1,430 controls, and 689 sex partners in four Latin American countries has made it possible to assess the influence of multiple factors upon the risk of invasive cervical cancer. The principal risk factors identified were the woman's age at first coitus, the number of her steady sex partners, her number of live births, the presence of DNA from human papillomavirus (HPV) types 16 or 18, a history of venereal disease, nonparticipation in early detection programs, and low socioeconomic status. There is good reason to believe that extensive detection programs directed mainly at high-risk groups in the Americas can reduce the high incidence of cervical cancer in this Region.
Herrero
R
R
Environmental Epidemiology Branch, National Cancer Institute, Bethesda, MD 20892.
Brinton
L A
LA
Reeves
W C
WC
Brenes
M M
MM
Tenorio
F
F
de Britton
R C
RC
Gaitán
E
E
Montalván
P
P
García
M
M
Rawls
W E
WE
D000328:Adult; D004279:DNA, Viral / Q000302:isolation & purification; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D027383:Papillomaviridae / Q000302:isolation & purification; D012098:Reproduction; D012307:Risk Factors; D012725:Sexual Behavior; D012747:Sexual Partners; D002583:Uterine Cervical Neoplasms / Q000209:etiology* / Q000473:pathology
D004279:DNA, Viral