Detection of canine distemper viral antigen in formalin-fixed and paraffin-embedded tissue of a fitch (Mustela putorius), using an immunoperoxidase technique.
The present study describes how a naturally infected fitch (Mustela putorius) caused an outbreak of canine distemper in a colony of insufficiently vaccinated dogs. The detection of canine distemper virus (CDV) on paraffin sections of different organs of the fitch and one of the dead dogs was achieved using a monoclonal antibody against the nucleocapsid protein (NP) of CDV and the avidin-biotin-peroxidase complex (ABC) technique.
Hewicker
M
M
Institut für Pathologie der Tierärztlichen Hochschule Hannover, Abt. für Immunpathologie.
Damsch
S
S
Trautwein
G
G
D000818:Animals; D000956:Antigens, Viral / Q000032:analysis*; D002335:Carnivora; D004196:Disease Outbreaks / Q000662:veterinary*; D004216:Distemper / Q000453:epidemiology*; D004217:Distemper Virus, Canine / Q000276:immunology*; D004285:Dogs; D005860:Germany, West / Q000453:epidemiology; D007124:Immunoenzyme Techniques
D000956:Antigens, Viral