title: Magnetic resonance imaging (MRI) effects on rat pineal neuroendocrine function.
abstract: This study investigated the effects of MRI on receptor-mediated activation of pineal gland indole biosynthesis. Exposure of rats to MRI reduced the effects of isoproterenol on pineal serotonin and N-acetylserotonin levels suggesting that strong magnetic fields and/or radio-frequency pulsing used in MRI inhibited beta-adrenergic activation of the gland. There was no effect of MRI on saline controls.
authors.affiliation: Department of Anatomy, Loyola University Stritch School of Medicine, Maywood, IL 60153.
authors.forename: R
authors.initials: R
authors.lastname: LaPorte
authors.forename: L
authors.initials: L
authors.lastname: Kus
authors.forename: R A
authors.initials: RA
authors.lastname: Wisniewski
authors.forename: M M
authors.initials: MM
authors.lastname: Prechel
authors.forename: B
authors.initials: B
authors.lastname: Azar-Kia
authors.forename: J A
authors.initials: JA
authors.lastname: McNulty
mesh_terms: D000818:Animals; D004574:Electromagnetic Fields; D055590:Electromagnetic Phenomena; D007545:Isoproterenol / Q000494:pharmacology; D008279:Magnetic Resonance Imaging; D008297:Male; D010870:Pineal Gland / Q000378:metabolism / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D011943:Receptors, Adrenergic, beta / Q000187:drug effects / Q000502:physiology*; D012701:Serotonin / Q000378:metabolism*
chemical_list: D011943:Receptors, Adrenergic, beta; D012701:Serotonin; D007545:Isoproterenol