title: Oat-bran cereal lowers serum total and LDL cholesterol in hypercholesterolemic men.
abstract: Oat bran lowers serum lipid concentrations in healthy and hyperlipidemic subjects. To determine the effects of a ready-to-eat oat-bran cereal on lipid concentrations, we fed control (corn flakes) and oat-bran cereal diets for 2 wk to 12 men with undesirably high serum total-cholesterol concentrations. Subjects were randomly assigned to one of the two diets upon admission to the metabolic ward. After completing the first diet, subjects completed 2 wk on the alternate diet. Intakes of carbohydrate, protein, fat, and cholesterol were virtually identical on the two diets. The oat-bran cereal provided 25 g oat bran/d. The oat-bran cereal diet compared with the corn flakes diet lowered serum total-cholesterol and serum LDL-cholesterol concentrations significantly by 5.4% (p less than 0.05) and 8.5% (p less than 0.025), respectively. Final body weights on each of the diets were similar. Ready-to-eat oat-bran cereal provides a practical means to incorporate soluble fiber into the diet to lower serum cholesterol.
authors.affiliation: Medical Service, Veterans Administration Medical Center, Lexington, KY.
authors.forename: J W
authors.initials: JW
authors.lastname: Anderson
authors.forename: D B
authors.initials: DB
authors.lastname: Spencer
authors.forename: C C
authors.initials: CC
authors.lastname: Hamilton
authors.forename: S F
authors.initials: SF
authors.lastname: Smith
authors.forename: J
authors.initials: J
authors.lastname: Tietyen
authors.forename: C A
authors.initials: CA
authors.lastname: Bryant
authors.forename: P
authors.initials: P
authors.lastname: Oeltgen
mesh_terms: D000368:Aged; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood*; D004043:Dietary Fiber / Q000494:pharmacology*; D002523:Edible Grain; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood*; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D015596:Nutrition Assessment; D014280:Triglycerides / Q000097:blood
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D004043:Dietary Fiber; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol