[An immunohistochemical study of estrogen receptors in thyroid carcinoma].
Estrogen receptors immunoreactivity (ER-IR) has been examined in 64 cases of human thyroid carcinomas. ER-IR was found to be located in the nucleus of cancer cells and was detected in 30 (57.7%) of 52 papillary carcinomas that were examined. Eleven cases showing a good number of ER-IR positive cancer cells revealed a lowered EORTC index of under 65, and no ER-IR was found in 12 anaplastic carcinomas. These findings indicate that ER-IR might generally bear a similar reciprocal relationship to the malignancy of a thyroid carcinoma.
Haruta
R
R
1st Dept. of Pathology, Hiroshima Univ. School of Med.
Ito
H
H
Takeichi
N
N
Matsuyama
T
T
Dohi
K
K
Tahara
E
E
D000328:Adult; D000367:Age Factors; D000368:Aged; D002291:Carcinoma, Papillary / Q000032:analysis / Q000473:pathology; D002467:Cell Nucleus / Q000032:analysis; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011960:Receptors, Estrogen / Q000032:analysis*; D012737:Sex Factors; D013964:Thyroid Neoplasms / Q000032:analysis* / Q000473:pathology
D011960:Receptors, Estrogen