Primary structure and functional expression of a high voltage activated calcium channel from rabbit lung.
The complete amino acid sequence of the receptor for organic calcium channel blockers (CaCB) from rabbit lung has been deduced by cloning and sequence analysis of the cDNA. Synthetic RNA derived from this cDNA induces the formation of a functional CaCB-sensitive high voltage activated calcium channel in Xenopus oocytes.
Biel
M
M
Medizinische Biochemie, Universität des Saarlandes, Homburg/Saar, FRG.
Ruth
P
P
Bosse
E
E
Hullin
R
R
Stühmer
W
W
Flockerzi
V
V
Hofmann
F
F
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015220:Calcium Channels / Q000378:metabolism / Q000502:physiology*; D002462:Cell Membrane / Q000502:physiology / Q000648:ultrastructure; D003001:Cloning, Molecular; D004558:Electric Stimulation; D005260:Female; D015870:Gene Expression; D008168:Lung / Q000378:metabolism / Q000502:physiology*; D008564:Membrane Potentials; D008565:Membrane Proteins / Q000235:genetics* / Q000502:physiology; D008961:Models, Structural; D008969:Molecular Sequence Data; D009865:Oocytes / Q000502:physiology; D011487:Protein Conformation; D012333:RNA, Messenger / Q000235:genetics; D011817:Rabbits; D011978:Receptors, Nicotinic / Q000235:genetics / Q000502:physiology*; D014982:Xenopus laevis
D015220:Calcium Channels; D008565:Membrane Proteins; D012333:RNA, Messenger; D011978:Receptors, Nicotinic