title: Effect of dietary sodium bicarbonate on leg structure in Duroc swine that differ genetically for leg weakness.
abstract: Two trials were conducted to evaluate the effect of dietary replacement of .30% sodium chloride (NaCl) with a sodium-equivalent amount of sodium bicarbonate (NaHCO3) on leg weakness in swine. Three lines of Duroc swine established by six generations of divergent selection for front leg structure were used. In the first trial, a total of 80 low-line (increased leg weakness), 75 high-line (decreased leg weakness), 80 control-line (intermediate leg weakness) and 80 high x low pigs were used. Pigs were assigned within litter to an experimental or control diet and tested from approximately 37 to 104 kg live weight. The experimental diet contained .43% NaHCO3, replacing .30% NaCl in the control diet. Pigs had ad libitum access to feed. In the second trial, 48 high- and 48 low-line pigs were fed the same diets from 29 to 104 kg. At the completion of each trial, pigs were scored for various leg traits. The model used for statistical analyses included the effects of replicate, genetic line, dietary treatment and the dietary treatment x genetic line interaction. Trials were analyzed separately. Results indicated that there was no significant improvement in clinical signs of leg weakness due to dietary supplementation with NaHCO3 for front leg structure and movement, rear leg movement or rear toe size. Rear hock angle was improved in Trial 1 (P less than .05) but was reduced in Trial 2 (P less than .10).(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Dept. of Anim. Sci., Iowa State University, Ames 50011.
authors.forename: C W
authors.initials: CW
authors.lastname: Ernst
authors.forename: M F
authors.initials: MF
authors.lastname: Rothschild
authors.forename: L L
authors.initials: LL
authors.lastname: Christian
authors.forename: R C
authors.initials: RC
authors.lastname: Ewan
mesh_terms: D000821:Animal Feed; D000818:Animals; D001639:Bicarbonates / Q000008:administration & dosage*; D004032:Diet; D005121:Extremities / Q000033:anatomy & histology*; D005260:Female; D006863:Hydrogen-Ion Concentration; D007794:Lameness, Animal / Q000235:genetics / Q000517:prevention & control*; D008297:Male; D011897:Random Allocation; D012964:Sodium / Q000008:administration & dosage*; D017693:Sodium Bicarbonate; D013552:Swine; D013553:Swine Diseases / Q000235:genetics / Q000517:prevention & control*
chemical_list: D001639:Bicarbonates; D017693:Sodium Bicarbonate; D012964:Sodium