title: Rhinocerebral mucormycosis: report of two cases.
abstract: Rhinocerebral mucormycosis developed in two poorly controlled diabetic patients with clinical manifestations of frontal headache, ophthalmoplegia, ptosis, proptosis, epistaxis and facial numbness. Early computed tomography (CT) of the head revealed fluid accumulation in paranasal sinuses. The diagnosis of this disease relied upon CT of the head, and biopsy or culture of the mucosa of sinuses. Remarkable improvement was noted following prompt surgical debridement and amphotericin-B therapy. We conclude that early diagnosis and aggressive treatment is the only way to save patient's life.
authors.affiliation: Department of Medicine, Veterans General Hospital Taichung, Taiwan, R.O.C.
authors.forename: M Y
authors.initials: MY
authors.lastname: Mui
authors.forename: P Y
authors.initials: PY
authors.lastname: Wang
authors.forename: L G
authors.initials: LG
authors.lastname: Chia
authors.forename: W L
authors.initials: WL
authors.lastname: Ho
mesh_terms: D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D001927:Brain Diseases / Q000000981:diagnostic imaging* / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D009091:Mucormycosis / Q000000981:diagnostic imaging* / Q000628:therapy; D009668:Nose Diseases / Q000000981:diagnostic imaging* / Q000628:therapy; D014057:Tomography, X-Ray Computed
chemical_list: D000666:Amphotericin B