Prediction of the interaction effects Ar+ laser-brain tumours by study of the photoacoustic spectroscopy of cerebral oncotypes.
A preliminary definition of light absorption spectra of brain neoplasm represents a correct approach to the laser therapy of cerebral tumours. The goal should be the identification of those oncotypes more sensive to the laser energy, allowing consequently a dosage of the energy proportional to the light absorption coefficient, reducing any side effects. With this purpose the coefficients of light-absorption of 63 different brain tumours have been analyzed and defined by means of photocoustic spectrometry. The study has been focused at wavelength of the Ar+ laser (4,600-6,000 A). The results show a close relationship between histology, degree of vascularization and/or pigmentation and light absorption: the more immature and/or pigmented oncotypes show the highest coefficients of optical absorption. In the laser therapy of these neoplasms it will be sufficient to use low powers and short exposure time.
De Tommasi
A
A
Chair of Neurosurgery, University of Bari, Italy.
Occhiogrosso
M
M
Vailati
G
G
Baldassarre
L
L
Cingolani
A
A
D000818:Animals; D001128:Argon; D001254:Astrocytoma / Q000473:pathology / Q000601:surgery; D001921:Brain / Q000166:cytology / Q000473:pathology*; D001932:Brain Neoplasms / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D002417:Cattle; D002528:Cerebellar Neoplasms / Q000473:pathology / Q000601:surgery; D005909:Glioblastoma / Q000473:pathology / Q000601:surgery; D006801:Humans; D053685:Laser Therapy; D007834:Lasers; D008527:Medulloblastoma / Q000473:pathology / Q000601:surgery; D008577:Meningeal Neoplasms / Q000473:pathology / Q000601:surgery; D008579:Meningioma / Q000473:pathology / Q000601:surgery
D001128:Argon