title: Total energy expenditure in burned children using the doubly labeled water technique.
abstract: Total energy expenditure (TEE) was measured in 15 burned children with the doubly labeled water technique. Application of the technique in burned children required evaluation of potential errors resulting from nutritional intake altering background enrichments during studies and from the high rate of water turnover relative to CO2 production. Five studies were discarded because of these potential problems. TEE was 1.33 +/- 0.27 times predicted basal energy expenditure (BEE), and in studies where resting energy expenditure (REE) was simultaneously measured, TEE was 1.18 +/- 0.17 times REE, which in turn was 1.16 +/- 0.10 times predicted BEE. TEE was significantly correlated with measured REE (r2 = 0.92) but not with predicted BEE. These studies substantiate the advantage of measuring REE to predict TEE in severely burned patients as opposed to relying on standardized equations. Therefore we recommend that optimal nutritional support will be achieved in convalescent burned children by multiplying REE by an activity factor of 1.2.
authors.affiliation: Shriners Burns Institute, Galveston, Texas 77550.
authors.forename: M I
authors.initials: MI
authors.lastname: Goran
authors.forename: E J
authors.initials: EJ
authors.lastname: Peters
authors.forename: D N
authors.initials: DN
authors.lastname: Herndon
authors.forename: R R
authors.initials: RR
authors.lastname: Wolfe
mesh_terms: D000293:Adolescent; D001835:Body Weight; D002056:Burns / Q000378:metabolism*; D002245:Carbon Dioxide / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D003903:Deuterium / Q000378:metabolism; D017666:Deuterium Oxide; D002149:Energy Intake; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D007553:Isotope Labeling / Q000379:methods; D008297:Male; D010103:Oxygen Isotopes; D011865:Radioisotope Dilution Technique; D014867:Water / Q000378:metabolism
chemical_list: D010103:Oxygen Isotopes; D014867:Water; D002245:Carbon Dioxide; D003903:Deuterium; D017666:Deuterium Oxide