Properties of voltage-dependent barium currents in neurons of pelvic parasympathetic ganglia of rabbit.
Properties of voltage-dependent barium current (IBa) were examined in parasympathetic neurons of the rabbit urinary bladder, in vitro. Transient low-threshold IBa was evoked by voltage jump from a holding potential (Vh) of -100 to -50 mV. Additional transient high-threshold IBa appeared at potentials more positive than -30 mV. Long-lasting high-threshold IBa was evoked at 0 to -20 mV. High-threshold currents were blocked by omega-conotoxin but not by dihydropyridines.
Tsurusaki
M
M
Department of Physiology, Kurume University School of Medicine, Japan.
Nishimura
T
T
Akasu
T
T
D000818:Animals; D001464:Barium / Q000502:physiology*; D002121:Calcium Channel Blockers / Q000494:pharmacology; D015220:Calcium Channels / Q000187:drug effects / Q000502:physiology; D002463:Cell Membrane Permeability / Q000502:physiology*; D004095:Dihydropyridines / Q000494:pharmacology; D004558:Electric Stimulation; D004594:Electrophysiology; D005726:Ganglia, Parasympathetic / Q000166:cytology / Q000502:physiology*; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D009474:Neurons / Q000502:physiology* / Q000648:ultrastructure; D010456:Peptides, Cyclic / Q000494:pharmacology; D011817:Rabbits; D020960:omega-Conotoxins
D002121:Calcium Channel Blockers; D015220:Calcium Channels; D004095:Dihydropyridines; D010456:Peptides, Cyclic; D020960:omega-Conotoxins; C053423:Conus magus toxin; D001464:Barium