title: Establishment of a B-lymphoblastoid cell line infected with Epstein-Barr-related virus from a cynomolgus monkey (Macaca fascicularis).
abstract: A B-lymphoblastoid cell line (Ts-B) was established from lymph nodes of an apparently healthy cynomolgus monkey. The cells were demonstrated to contain Epstein-Barr virus-related antigens. Moreover, herpesvirus particles were found in the cells by electron microscopy. The cell-free culture medium transformed lymphocytes of cynomolgus rhesus monkeys, and of Japanese monkeys.
authors.affiliation: Tsukuba Primate Center for Medical Science, NIH, Ibaragi, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Fujimoto
authors.forename: K
authors.initials: K
authors.lastname: Terato
authors.forename: J
authors.initials: J
authors.lastname: Miyamoto
authors.forename: H
authors.initials: H
authors.lastname: Ishiko
authors.forename: M
authors.initials: M
authors.lastname: Fujisaki
authors.forename: F
authors.initials: F
authors.lastname: Cho
authors.forename: S
authors.initials: S
authors.lastname: Honjo
mesh_terms: D000818:Animals; D000956:Antigens, Viral / Q000032:analysis; D001402:B-Lymphocytes / Q000166:cytology / Q000382:microbiology*; D002460:Cell Line; D002461:Cell Line, Transformed; D002472:Cell Transformation, Viral; D002999:Clone Cells; D003470:Culture Media; D019309:Epstein-Barr Virus Nuclear Antigens; D005455:Fluorescent Antibody Technique; D004854:Herpesvirus 4, Human / Q000276:immunology / Q000502:physiology* / Q000648:ultrastructure; D008198:Lymph Nodes / Q000166:cytology*; D008251:Macaca; D008252:Macaca fascicularis; D008253:Macaca mulatta; D008297:Male; D008854:Microscopy, Electron
chemical_list: D000956:Antigens, Viral; D003470:Culture Media; D019309:Epstein-Barr Virus Nuclear Antigens