[The effect of the acute administration of ethanol on the realization of behavior and its neuronal support].
In experiments on rabbits trained to instrumental food procuring behaviour it was cleared up, which changes of activity of neurones of the limbic cortical area corresponded to disturbances of this behaviour (increase in time of realization and in the number of errors) caused by intraperitoneal injection of 12% ethanol solution in a dose of 1 g/kg. In comparison with control (administration of isotonic solution), the number of active cells singled out in the microelectrode track was reduced by 1/3; the pattern of behavioural specialization of neurones involved in provision of the disturbed behaviour was changed. The content of neurones of the most recent systems formed during animals learning instrumental behaviour, decreased from 27 to 11%, and of neurones providing for realization of systems formed at previous stages of individual development increased from 18 to 36%.
Aleksandrov
Iu I
IuI
Grinchenko
Iu V
IuV
Svetlaev
I A
IA
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects* / Q000502:physiology; D003216:Conditioning, Operant / Q000187:drug effects / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D000431:Ethanol / Q000008:administration & dosage*; D005247:Feeding Behavior / Q000187:drug effects / Q000502:physiology; D008032:Limbic System / Q000187:drug effects / Q000502:physiology; D008297:Male; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D011817:Rabbits; D011930:Reaction Time / Q000187:drug effects / Q000502:physiology
D000431:Ethanol
Vliianie ostrogo vvedeniia étanola na realizatsiiu povedeniia i ego neĭronnoe obespechenie.