Circulating opioid peptides during thermal stress.
In the present study we have examined the response of endogenous opiates (beta-EP and Met-enk) and ACTH to a particular type of thermal stimulus such as sauna in 8 young healthy subjects. Sauna-induced hyperthermia resulted in an increase of plasma beta-EP and ACTH, but appeared to have no significant effect on circulating Met-enk. The different responses of ACTH, beta-EP and Met-enk to heat exposure indicate that hyperthermia represents a form of stress, which can trigger off a well-defined neuroendocrine reaction.
Vescovi
P P
PP
Istituto di Clinica Medica Generale University of Parma, Italy.
Gerra
G
G
Pioli
G
G
Pedrazzoni
M
M
Maninetti
L
L
Passeri
M
M
D000324:Adrenocorticotropic Hormone / Q000097:blood; D000328:Adult; D001831:Body Temperature; D004744:Enkephalin, Methionine / Q000097:blood*; D006339:Heart Rate; D006358:Hot Temperature; D006801:Humans; D008297:Male; D011863:Radioimmunoassay; D029002:Steam Bath; D013312:Stress, Physiological / Q000097:blood* / Q000503:physiopathology; D001615:beta-Endorphin / Q000097:blood*
D004744:Enkephalin, Methionine; D001615:beta-Endorphin; D000324:Adrenocorticotropic Hormone