A case of adenoid cystic carcinoma of the parotid gland--an immunohistological study.
We treated a case of adenoid cystic carcinoma that occurred in the right parotid gland of a 51-year-old woman. Although the tumor, including part of the parotid gland, was resected based on a clinical diagnosis of pleomorphic adenoma, it was later diagnosed as adenoid cystic carcinoma of mixed cribriform-solid type by histopathological examination after resection. Therefore, postoperative irradiation with a dose of 51 Gy was performed. Immunohistological examination of the resected specimen showed that the profiles of carbohydrate antigens were Lewis (a-, b+) in both the tumor and surrounding normal parotid tissue. NCC-SG-007 antigen was observed in the tumor tissue but not in the normal parotid gland, suggesting that this antigen was associated with the tumor.
Takayama
Y
Y
1st Department of Oral Surgery, Nihon University School of Dentistry, Tokyo, Japan.
Suzuki
T
T
Shirano
T
T
Yamanoi
H
H
Hori
M
M
Tanaka
H
H
Kusama
K
K
Moro
I
I
D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D003528:Carcinoma, Adenoid Cystic / Q000737:chemistry / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007983:Lewis Blood Group Antigens; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000737:chemistry / Q000473:pathology*
D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor; D007983:Lewis Blood Group Antigens