title: A validation study on the reproducibility of transcranial Doppler velocimetry.
abstract: The transcranial Doppler method for the measurement of intracranial arterial blood flow velocity is a useful noninvasive technique with a number of applications. The present study validated the reproducibility of this method for repeated measurements of flow velocity in the middle cerebral and basilar arteries. Fifteen healthy volunteers were studied. Measurements were made twice by one examiner and once by another in a single day and again by the first examiner on another day. The reproducibility was evaluated by calculating the correlation coefficient (r) and the coefficient of variation (CV) of the difference between the values obtained from each pair of measurements. Although depending on the examiner, the time interval between the examinations and the vessels studied some differences were noted in the reproducibility, both the r (0.69-0.95) and CV (6.7%-19.5%) values in the whole study were good enough to warrant the applicability of this method for the repeated measurements of the intracranial arterial blood flow velocity in future studies.
authors.affiliation: First Department of Internal Medicine, Osaka University Medical School, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Maeda
authors.forename: H
authors.initials: H
authors.lastname: Etani
authors.forename: N
authors.initials: N
authors.lastname: Handa
authors.forename: M
authors.initials: M
authors.lastname: Tagaya
authors.forename: N
authors.initials: N
authors.lastname: Oku
authors.forename: B H
authors.initials: BH
authors.lastname: Kim
authors.forename: M
authors.initials: M
authors.lastname: Naka
authors.forename: N
authors.initials: N
authors.lastname: Kinoshita
authors.forename: T
authors.initials: T
authors.lastname: Nukada
authors.forename: R
authors.initials: R
authors.lastname: Fukunaga
mesh_terms: D002536:Cerebral Arteries / Q000033:anatomy & histology / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D012039:Regional Blood Flow; D015203:Reproducibility of Results; D013997:Time Factors; D014463:Ultrasonography