Neuropeptide Y inhibits corticosterone secretion by isolated rat adrenocortical cells.
Studies with isolated rat adrenocortical cells have shown that neuropeptide Y (NPY) inhibits both basal and ACTH-stimulated corticosterone secretion. These results suggest the regulatory role of NPY in corticosterone secretion from the adrenal gland, especially during stress.
Malendowicz
L K
LK
Department of Histology and Embryology, Poznań Academy of Medicine, Poland.
Leśniewska
B
B
Miśkowiak
B
B
D000302:Adrenal Cortex / Q000378:metabolism*; D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000818:Animals; D002478:Cells, Cultured; D003345:Corticosterone / Q000378:metabolism*; D005260:Female; D066298:In Vitro Techniques; D009478:Neuropeptide Y / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D012636:Secretory Rate / Q000187:drug effects
D009478:Neuropeptide Y; D000324:Adrenocorticotropic Hormone; D003345:Corticosterone