[Acute myocardial infarction induced by lung cancer chemotherapy with cisplatin and etoposide].
From June of 1986 to May of 1989, we encountered 78 cases of lung cancer and administered CDDP and etoposide, orally and intravenously. We found 3 cases of acute myocardial infarction (AMI) onset after this chemotherapy regimen. It is important to detect AMI onset as soon as possible. We must take prophylactic procedures for patients with coronary risk factors who have had radiation therapy previously.
Tsutsumi
T
T
National Kyoto Hospital.
Ozawa
Y
Y
Kawakami
A
A
Fujii
H
H
Asamoto
H
H
D000230:Adenocarcinoma / Q000188:drug therapy*; D000368:Aged; D018288:Carcinoma, Small Cell / Q000188:drug therapy*; D002945:Cisplatin / Q000009:adverse effects*; D004562:Electrocardiography; D005047:Etoposide / Q000009:adverse effects*; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000139:chemically induced* / Q000503:physiopathology / Q000517:prevention & control
D005047:Etoposide; D002945:Cisplatin