[Changes in RBC Ca2(+)-ATPase activity and red-cell calcium concentration during dialysis in patients with uremia].
The changes of RBC Ca2(+)-ATPase activity and red cell calcium concentration during dialysis were observed in 19 patients with uremia. The results showed that in 12 patients treated by haemodialysis the RBC Ca2(+)-ATPase activity was lowered an average of 35 U than that in the controls (P less than 0.001); whereas red cell calcium was increased about 5 times (P less than 0.001). After a four-hour haemodialysis, the Ca2(+)-ATPase activity increased 20 U (P less than 0.05); and red cell calcium decreased 45 mumol/L cells (P less than 0.05). In 7 patients treated by CAPD the RBC Ca2(+)-ATPase activity was reduced to 60% of that in the controls (P less than 0.001); and red cell calcium was about 5 times as high as that in the controls (P less than 0.001). After one month of CAPD, the Ca2(+)-ATPase activity increased only 10 U (P greater than 0.05); but red cell calcium decreased 66 mumol/L cells (P less than 0.01).
Yang
Y
Y
D000328:Adult; D000368:Aged; D002118:Calcium / Q000378:metabolism*; D000252:Calcium-Transporting ATPases / Q000378:metabolism*; D004910:Erythrocyte Membrane / Q000201:enzymology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory; D006435:Renal Dialysis; D014511:Uremia / Q000378:metabolism* / Q000628:therapy
D000252:Calcium-Transporting ATPases; D002118:Calcium