Stimulatory signals for secretion in a cultured mast cell line: evidence for activation of phospholipase C through more than one G-protein.
Beaven
M A
MA
Laboratory of Chemical Pharmacology, National Heart, Lung, and Blood Institute, Bethesda, MD 20892.
Gonzaga
H M
HM
D000241:Adenosine / Q000031:analogs & derivatives / Q000494:pharmacology; D000818:Animals; D000944:Antigens, Differentiation, B-Lymphocyte / Q000235:genetics / Q000276:immunology; D002118:Calcium / Q000502:physiology; D000242:Cyclic AMP / Q000494:pharmacology; D006152:Cyclic GMP / Q000494:pharmacology; D004789:Enzyme Activation; D005089:Exocytosis; D019204:GTP-Binding Proteins / Q000145:classification / Q000502:physiology*; D007073:Immunoglobulin E / Q000276:immunology; D015640:Ion Channel Gating; D015471:Leukemia, Basophilic, Acute; D008407:Mast Cells / Q000187:drug effects / Q000378:metabolism*; D051381:Rats; D011961:Receptors, Fc / Q000235:genetics / Q000276:immunology; D017455:Receptors, IgE; D015290:Second Messenger Systems; D014407:Tumor Cells, Cultured; D010738:Type C Phospholipases / Q000378:metabolism*
D000944:Antigens, Differentiation, B-Lymphocyte; D011961:Receptors, Fc; D017455:Receptors, IgE; D007073:Immunoglobulin E; D000242:Cyclic AMP; D010738:Type C Phospholipases; D019204:GTP-Binding Proteins; D006152:Cyclic GMP; D000241:Adenosine; D002118:Calcium