Peculiarities of neural regulation of the thyroid, adrenocortical and testicular functions in old age.
The age changes of neural control over the function of the thyroid, adrenal cortex and testicles were examined in adult (6 months) and old (28 months) male rats. In old age, there was a weakening of adrenergic control of thyroidogenesis, alpha-adrenergic and M-cholinergic control of glucocorticoid function of the adrenal cortex and reduction of adrenergic and M-cholinergic influences in the regulation of steroidogenic function of the testicles.
Frolkis
V V
VV
Experimental Department, Institute of Gerontology, Kiev, U.S.S.R.
Gorban
E N
EN
Moroz
E V
EV
D000302:Adrenal Cortex / Q000294:innervation* / Q000378:metabolism / Q000502:physiology; D000324:Adrenocorticotropic Hormone / Q000097:blood; D000375:Aging / Q000378:metabolism / Q000502:physiology*; D000818:Animals; D001285:Atropine / Q000494:pharmacology; D003983:Dibenzylchlorethamine / Q000494:pharmacology; D007664:Ketosteroids / Q000097:blood; D008297:Male; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D012110:Reserpine / Q000494:pharmacology; D013737:Testis / Q000294:innervation* / Q000378:metabolism / Q000502:physiology; D013739:Testosterone / Q000097:blood; D013961:Thyroid Gland / Q000294:innervation* / Q000378:metabolism / Q000502:physiology; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D007664:Ketosteroids; D014284:Triiodothyronine; D013739:Testosterone; D003983:Dibenzylchlorethamine; D001285:Atropine; D012110:Reserpine; D000324:Adrenocorticotropic Hormone; D013972:Thyrotropin; D011433:Propranolol; D013974:Thyroxine