[Successful treatment of recurrent ulcerative stomatitis, associated with cellular immune defect and hypozincaemia, by oral administration of zinc sulfate].
The author observed cellular immune defect confirmed by lymphoblast transformation and hypozincemia in a 15-year old boy whose ulcerative stomatitis had been recurring for 6 years monthly and was treated without success besides local treatment with chronic administration of steroid, isoprinosin, interferon and lysosim. 3 X 50 mg of zinc sulphate given per os daily for 3 months resulted in permanent clinically symptom free condition and in the normalization of the lymphoblast transformation rate.
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Budai Gyermekkórház Rendelóintézet.
D000284:Administration, Oral; D000293:Adolescent; D005892:Gingivitis, Necrotizing Ulcerative / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D007153:Immunologic Deficiency Syndromes / Q000097:blood* / Q000150:complications; D008297:Male; D012008:Recurrence; D013431:Sulfates / Q000008:administration & dosage / Q000627:therapeutic use*; D015032:Zinc / Q000008:administration & dosage / Q000097:blood / Q000172:deficiency* / Q000627:therapeutic use*; D019287:Zinc Sulfate
D013431:Sulfates; D019287:Zinc Sulfate; D015032:Zinc
Celluláris immundefektussal és hypozincaemiával járó recidiváló stomatitis ulcerosa sikeres kezelése per os adott cinkszulfáttal.