Separation of [18F]fluoride from [18O]water using anion exchange resin.
The separation of no carrier added [18F]fluoride from 18O enriched water is described. The [18F]fluoride is deposited on Dowex 1 x 10 anion exchange resin as the water is passed through. The 18F is removed by elution with a dilute solution of cesium carbonate or potassium carbonate in water. Recovery of the 18F is greater than 95% efficient with a loss of 18O water of less than 5 microL from a volume of 3 mL.
Schlyer
D J
DJ
Department of Chemistry, Brookhaven National Laboratory, Upton, NY 11973.
Bastos
M A
MA
Alexoff
D
D
Wolf
A P
AP
D000837:Anion Exchange Resins; D005462:Fluorine Radioisotopes / Q000302:isolation & purification*; D010103:Oxygen Isotopes; D014867:Water / Q000032:analysis*
D000837:Anion Exchange Resins; D005462:Fluorine Radioisotopes; D010103:Oxygen Isotopes; D014867:Water