[Production of superoxide free radicals by peripheral blood leukocytes in patients with psoriasis treated by the Re-PUVA-C method].
The investigations were carried out in 20 patients with severe forms of psoriasis, and in 18 healthy subjects. The generation of free superoxide radicals by polymorphonuclear leukocytes of peripheral blood was evaluated by Bellavite et al. (1983) method by use superoxide dismutase of Sigma firm. The obtained results may confirm alterations in PMNL functions in patients with psoriasis observed by many authors. It may confirm the probability of damage of membrane structures and alterations in their bactericidal functions.
Kaszuba
A
A
Katedry i Kliniki Dermatologicznej WAM w Lodzi.
Błaszczyk
J
J
Ruszczak
Z
Z
Kedziora
J
J
Czarnecki
M
M
Kozłowska
M
M
D000328:Adult; D005260:Female; D005609:Free Radicals; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000378:metabolism*; D011701:PUVA Therapy / Q000379:methods*; D011565:Psoriasis / Q000097:blood* / Q000188:drug therapy / Q000378:metabolism; D013481:Superoxides / Q000097:blood* / Q000378:metabolism
D005609:Free Radicals; D013481:Superoxides
Generowanie wolnych rodników ponadtlenkowych przez leukocyty krwi obwodowej u chorych na łuszczyce leczonych metoda Re-PUVA-C.