title: [Limited proteolysis activation syndrome in surgery].
abstract: Under consideration is an original author's conception, formulated previously, of the syndrome of activation of limited proteolysis as an obligatory pathogenetic link of all pathological processes including the alteration at the tissue level as applied to surgical diseases. A universal character of the syndrome in acute and chronic surgical diseases and traumas, its role in their pathogenesis was shown in 1107 patients and 130 experimental animals. Variants of the course of the syndrome in different diseases are considered both in the postoperative and posttraumatic periods. The significance of the syndrome of activation of limited proteolysis for practical surgery is discussed.
authors.forename: V V
authors.initials: VV
authors.lastname: Chalenko
mesh_terms: D002318:Cardiovascular Diseases / Q000201:enzymology / Q000601:surgery*; D004066:Digestive System Diseases / Q000201:enzymology / Q000601:surgery*; D004789:Enzyme Activation / Q000502:physiology; D006801:Humans; D010447:Peptide Hydrolases / Q000378:metabolism*; D011183:Postoperative Complications / Q000201:enzymology* / Q000209:etiology; D014947:Wounds and Injuries / Q000201:enzymology / Q000601:surgery*
chemical_list: D010447:Peptide Hydrolases
vernacular_title: Sindrom aktivatsii ogranichennogo proteoliza v khirurgii.