title: [Experimental generalized herpes simplex in guinea pigs with retrobulbar infection].
abstract: Modelling of generalized herpetic infection of Guinea pigs is described. It took the course in the form of acute or subacute recurring process with either involvement of separate internal organs, or disseminated involvement of all visceral organs, or principal involvement of subcortical structures of the brain, or involvement of the brain and spinal marrow and marked vegetative failures. Signs of vasculitis; development of disseminated intravascular coagulation (DIC) syndrome and CNS demyelinization are detected in animals during the terminal period.
authors.forename: A G
authors.initials: AG
authors.lastname: Kolomiets
authors.forename: G P
authors.initials: GP
authors.lastname: Duboĭskaia
authors.forename: S A
authors.initials: SA
authors.lastname: Guzov
authors.forename: I I
authors.initials: II
authors.lastname: Protas
authors.forename: L A
authors.initials: LA
authors.lastname: Petrashevich
authors.forename: N D
authors.initials: ND
authors.lastname: Kolomiets
authors.forename: V I
authors.initials: VI
authors.lastname: Votiakov
mesh_terms: D000208:Acute Disease; D000818:Animals; D004195:Disease Models, Animal; D004679:Encephalomyelitis / Q000209:etiology* / Q000473:pathology; D006168:Guinea Pigs; D006561:Herpes Simplex / Q000150:complications* / Q000473:pathology; D009336:Necrosis; D009902:Optic Neuritis / Q000150:complications* / Q000473:pathology; D012008:Recurrence; D018139:Simplexvirus / Q000472:pathogenicity*
vernacular_title: Eksperimental'naia generalizovannaia gerpeticheskaia infektsiia u morskikh svinok pri retrobul'barnom zarazhenii.