Herpes simplex virus type 2 meningitis without genital lesions: an immunoblot study.
Two sexually active female patients presented with acute meningitis. The CSF abnormalities were severe and persistent. In spite of the absence of genital lesions, serological studies revealed a primary infection by herpes simplex virus type 2. An immunoblot study revealed intrathecal synthesis of anti-herpes antibodies early in the course of the disease.
Boucquey
D
D
Laboratory of Neurochemistry, Cliniques Universitaires Saint-Luc, Brussels, Belgium.
Chalon
M P
MP
Sindic
C J
CJ
Lamy
M E
ME
Laterre
C
C
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005831:Genital Diseases, Female / Q000150:complications; D006801:Humans; D015151:Immunoblotting; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D008587:Meningitis, Viral / Q000097:blood / Q000134:cerebrospinal fluid / Q000150:complications / Q000175:diagnosis*; D018139:Simplexvirus / Q000302:isolation & purification*
D007074:Immunoglobulin G; D007075:Immunoglobulin M