Large unit conductance voltage chloride channels are expressed in mouse neural crest cells and embryonic dorsal root ganglion cells.
The early expression of voltage-activated chloride channels of large unitary conductance (450 pS in symmetrical 140 mM KCl) was demonstrated using patch-clamp techniques in two preparations: (i) neural crest cells isolated from 9-day-old (E9) mouse embryos and (ii) acutely isolated dorsal root ganglion cells isolated from E12 mouse embryos. Properties of these ionic channels have been analyzed using single channel recordings and the group mean of these single channels.
Rabasseda
X
X
Laboratoire de Neurobiologie Cellulaire et Moléculaire, CNRS, Gif sur Yvette, France.
Valmier
J
J
Larmet
Y
Y
Simonneau
M
M
D000818:Animals; D002478:Cells, Cultured; D018118:Chloride Channels; D002712:Chlorides / Q000378:metabolism / Q000502:physiology*; D005727:Ganglia, Spinal / Q000196:embryology / Q000502:physiology*; D008564:Membrane Potentials; D008565:Membrane Proteins / Q000378:metabolism / Q000502:physiology*; D051379:Mice; D009432:Neural Crest / Q000166:cytology / Q000502:physiology*
D018118:Chloride Channels; D002712:Chlorides; D008565:Membrane Proteins