title: [Graft rejection reaction and immunosuppression following heart transplantation].
abstract: Acute rejection is the most important factor influencing mortality after heart transplant. Acute rejection occurs at least once in over 95% of the patients in the early phase after heart transplant. In the vast majority of episodes of acute rejection clinical symptoms are absent. The regular performance of endomyocardial biopsy after heart transplant allows histological diagnosis of rejection episodes as well as follow-up control of rejection treatment. This overview points to the major problems regarding acute rejection and immunosuppressive regimen in heart transplant recipients.
authors.affiliation: Kardiologie und Herzgefässchirurgie, Universitätsspital Zürich.
authors.forename: L
authors.initials: L
authors.lastname: Leonardi
authors.forename: A
authors.initials: A
authors.lastname: Lüthy
authors.forename: C
authors.initials: C
authors.lastname: Mondada
authors.forename: M
authors.initials: M
authors.lastname: Waser
authors.forename: A
authors.initials: A
authors.lastname: Laske
authors.forename: M
authors.initials: M
authors.lastname: Turina
authors.forename: A
authors.initials: A
authors.lastname: Gallino
mesh_terms: D006084:Graft Rejection / Q000187:drug effects*; D016027:Heart Transplantation / Q000276:immunology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D011183:Postoperative Complications / Q000517:prevention & control; D012307:Risk Factors; D014181:Transplantation Immunology / Q000187:drug effects
chemical_list: D007166:Immunosuppressive Agents
vernacular_title: Abstossungsreaktion und Immunosuppression nach Herztransplantation.