title: Review of the development and current status of techniques for monitoring embryonic and fetal development in the first trimester of pregnancy.
abstract: This review is confined to the historical background and development of the 2 principal methods of chorionic villus sampling. The failure rate and incidence of fetal losses are presented for a variety of instruments. Early referral is essential to optimise the use of these techniques.
authors.affiliation: Department of Obstetrics and Gynaecology, University College and Middlesex School of Medicine, London, England.
authors.forename: H
authors.initials: H
authors.lastname: Ward
mesh_terms: D015193:Chorionic Villi Sampling / Q000379:methods*; D005260:Female; D005313:Fetal Death; D006801:Humans; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011296:Prenatal Diagnosis / Q000379:methods*