[Study of xanthine oxidase activity in the brain tissue after administration of dalargin during myoplegia].
Effect of Dalargin (40 micrograms/kg) on xanthine-oxidase (X) activity in experimental Arduan-induced myoplegia (0.1 mg/kg) was studied in the brain tissue of 70 rats under inhalation anesthesia and artificial ventilation. Neither Dalargin nor Arduan was found separately to induce statistically significant changes in X activity. Dalargin injections in myoplegia caused significant (24.7%) reduction of the enzyme's activity.
Korotkina
R N
RN
Shloznikov
B M
BM
Donich
S G
SG
Grebenchikov
O A
OA
Sitnikov
A V
AV
Karelin
A A
AA
D015113:Androstane-3,17-diol / Q000031:analogs & derivatives / Q000494:pharmacology*; D000732:Androstanols / Q000494:pharmacology*; D000769:Anesthesia, Inhalation; D000818:Animals; D001921:Brain / Q000201:enzymology*; D004743:Enkephalin, Leucine / Q000031:analogs & derivatives* / Q000494:pharmacology; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives*; D008297:Male; D009466:Neuromuscular Blocking Agents / Q000494:pharmacology*; D003473:Neuromuscular Nondepolarizing Agents / Q000494:pharmacology*; D017300:Pipecuronium; D010879:Piperazines / Q000494:pharmacology*; D051381:Rats; D012121:Respiration, Artificial; D013565:Sympatholytics / Q000494:pharmacology*; D014969:Xanthine Oxidase / Q000378:metabolism*
D000732:Androstanols; D009466:Neuromuscular Blocking Agents; D003473:Neuromuscular Nondepolarizing Agents; D010879:Piperazines; D013565:Sympatholytics; D017300:Pipecuronium; D015113:Androstane-3,17-diol; D004743:Enkephalin, Leucine; D016308:Enkephalin, Leucine-2-Alanine; D014969:Xanthine Oxidase; C040996:enkephalin-Leu, Ala(2)-Arg(6)-
Izuchenie aktivnosti ksantinoksidazy v tkani golovnogo mozga pri vvedenii dalargina na fone mioplegii.