Sylvaticin: a new cytotoxic and insecticidal acetogenin from Rollinia sylvatica (Annonaceae).
Sylvaticin (I), a new tetrahydroxy annonaceous acetogenin with nonadjacent tetrahydrofuran rings, has been isolated from the dried fruits of Rollinia sylvatica St. Hil. (Annonaceae). This compound is extremely cytotoxic to human tumor cells and shows promising insect control properties.
Mikolajczak
K J
KJ
USDA-ARS, Northern Regional Research Center, Peoria, Illinois 61604.
Madrigal
R V
RV
Rupprecht
J K
JK
Hui
Y H
YH
Liu
Y M
YM
Smith
D L
DL
McLaughlin
J L
JL
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic; D055598:Chemical Phenomena; D002621:Chemistry; D005663:Furans / Q000032:analysis / Q000276:immunology*; D008401:Gas Chromatography-Mass Spectrometry; D007306:Insecticides; D009682:Magnetic Resonance Spectroscopy; D010936:Plant Extracts / Q000032:analysis / Q000494:pharmacology*
D000972:Antineoplastic Agents, Phytogenic; D005663:Furans; D007306:Insecticides; D010936:Plant Extracts; C063434:sylvaticin