Very high CA 125 levels during early first trimester in three cases of spontaneous abortion with chromosomal abnormalities.
Three women with very elevated, early-first-trimester CA 125 levels spontaneously aborted but not until later in the first trimester or early in the second trimester. All three products of conception showed chromosomal abnormalities. Further investigation is warranted to see if high CA 125 levels might be predictive of abnormal karyotypes.
Check
J H
JH
Department of Obstetrics and Gynecology, Cooper Hospital/University Medical Center, Camden, New Jersey.
Nowroozi
K
K
Vaze
M
M
Wapner
R
R
Seefried
L
L
D000022:Abortion, Spontaneous / Q000235:genetics / Q000276:immunology*; D000328:Adult; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis*; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D005260:Female; D005328:Fetal Viability; D006801:Humans; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D014463:Ultrasonography
D015295:Antigens, Tumor-Associated, Carbohydrate