title: [Cytochrome-C in the treatment of patients with acute myocardial infarct].
abstract: Sixty-eight patients with acute macrofocal myocardial infarction were subdivided in two groups depending on the kind of treatment: routine (nitrates, beta-blocking agents, calcium antagonists) and cytochrom-C. It was found that cytochrom-C produced a positive effect on the indices of myoglobin and cardiac fractions of lactatedehydrogenase-1 and lactatedehydrogenase-2. It is shown that inclusion of cytochrom-C during the first hours of treatment of patients with macrofocal myocardial infarction resulted in an improvement of tissue breathing and amelioration of the peri-infarction zone state.
authors.forename: B N
authors.initials: BN
authors.lastname: Bezborod'ko
authors.forename: I A
authors.initials: IA
authors.lastname: Shekhunova
mesh_terms: D000368:Aged; D003574:Cytochrome c Group / Q000627:therapeutic use*; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007527:Isoenzymes; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000188:drug therapy*; D009211:Myoglobin / Q000097:blood
chemical_list: D003574:Cytochrome c Group; D007527:Isoenzymes; D009211:Myoglobin; D007770:L-Lactate Dehydrogenase
vernacular_title: Tsitokhrom-C v lechenii bol'nykh ostrym infarktom miokarda.