title: The relative proportion of H1(0) and A24 is reversed in oligodendrocytes during rat brain development.
abstract: 1. The histone complement of oligodendrocyte chromatin at different stages of brain development was studied after acid extraction of nuclei. 2. HCl-soluble proteins were analyzed by different electrophoretic techniques. 3. Our results show an increase in the concentration of histone H1(0) with differentiation. 4. The increase in H1(0) is accompanied by a concomitant decrease in the total amount of the ubiquitinated form of histone H2A (A24).
authors.affiliation: Dipartimento di Biologia Cellulare e dello Sviluppo, Università degli Studi, Palermo, Italy.
authors.forename: I
authors.initials: I
authors.lastname: Di Liegro
authors.forename: A
authors.initials: A
authors.lastname: Cestelli
mesh_terms: D000375:Aging / Q000378:metabolism*; D000818:Animals; D001921:Brain / Q000254:growth & development / Q000378:metabolism*; D006657:Histones / Q000378:metabolism* / Q000502:physiology; D009836:Oligodendroglia / Q000378:metabolism* / Q000502:physiology; D051381:Rats; D014452:Ubiquitins
chemical_list: D006657:Histones; D014452:Ubiquitins