title: [A comparative analysis of the polypeptides of the the Sindbis and Karelian fever viruses].
abstract: In pulse-chase experiments with Karelian fever virus-infected cells, proteins were found with molecular weights of 130, 98, 78, and 62 kD of which the first, second and fourth were classified as polypeptide precursors of the structural proteins of virion. The molecular weights of proteins E1, E2 and C of 52, 47 and 34 kD, respectively, as well as isoelectric points of isolated glycoproteins (pI E1 = 6.3, pI E2 = 8.4) were similar in KFV (strain Leiv-9298) and Sindbis virus (strain AR339). The antigenic similarity of the strains under study in neutralization test with hyperimmune sera, the identity of physicochemical characteristics of the structural proteins of KFV and prototype Sindbis virus strain suggest a close relationship of the Leiv-9298 strain to the Afro-European variants of Sindbis virus.
authors.forename: L V
authors.initials: LV
authors.lastname: Uryvaev
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Zlobin
authors.forename: L K
authors.initials: LK
authors.lastname: Berezina
authors.forename: K S
authors.initials: KS
authors.lastname: Ionova
authors.forename: O P
authors.initials: OP
authors.lastname: Glushchenko
authors.forename: N A
authors.initials: NA
authors.lastname: Parasiuk
authors.forename: T M
authors.initials: TM
authors.lastname: Skvortsova
authors.forename: D K
authors.initials: DK
authors.lastname: L'vov
mesh_terms: D000524:Alphavirus / Q000032:analysis* / Q000276:immunology / Q000302:isolation & purification; D000956:Antigens, Viral / Q000032:analysis; D003429:Cross Reactions; D004591:Electrophoresis, Polyacrylamide Gel / Q000379:methods; D007525:Isoelectric Focusing / Q000379:methods; D008970:Molecular Weight; D009500:Neutralization Tests; D010455:Peptides / Q000032:analysis*; D012845:Sindbis Virus / Q000032:analysis* / Q000276:immunology / Q000302:isolation & purification
chemical_list: D000956:Antigens, Viral; D010455:Peptides
vernacular_title: Sravnitel'nyĭ analiz polipeptidov virusov Sindbis i karel'skoĭ likhoradki.