Hepatoblastoma characterized by trisomy 20 and double minutes.
Karyotypic study of two hepatoblastomas revealed trisomies for chromosome 20 and the presence of double minutes (dmin). These cases are the second and third examples of trisomy 20 in hepatoblastoma and are the first examples of dmins in this rare childhood tumor.
Mascarello
J T
JT
Genetic Services, Children's Hospital and Health Center, San Diego, CA 92123.
Jones
M C
MC
Kadota
R P
RP
Krous
H F
HF
D006528:Carcinoma, Hepatocellular / Q000235:genetics*; D002890:Chromosomes, Human, Pair 20; D006801:Humans; D007223:Infant; D007621:Karyotyping; D008113:Liver Neoplasms / Q000235:genetics*; D008297:Male; D014314:Trisomy