title: [Suspected germ cell tumor in bilateral basal ganglia with progressive dystonia].
abstract: We report an 11-year-old boy with left pyramidal signs followed by progressive dystonia, mental deterioration, bradykinesia and bradyarthria. Evaluation included a CT scan which showed bilateral lesions in the basal ganglia, and an elevated serum B-HCG. Those findings suggested a germ cell tumor. The patient was treated with radiation therapy with improvement in neurologic deficits, decreased size of the lesions on CT and a decline in serum B-HCG. The clinical response to radiation treatment is compatible with a germ cell tumor.
authors.affiliation: Department of Pediatrics, Nagoya University School of Medicine.
authors.forename: M
authors.initials: M
authors.lastname: Nakamura
authors.forename: K
authors.initials: K
authors.lastname: Watanabe
authors.forename: T
authors.initials: T
authors.lastname: Kobayashi
authors.forename: T
authors.initials: T
authors.lastname: Negoro
authors.forename: K
authors.initials: K
authors.lastname: Aso
authors.forename: S
authors.initials: S
authors.lastname: Furune
authors.forename: I
authors.initials: I
authors.lastname: Takahashi
authors.forename: N
authors.initials: N
authors.lastname: Yamamoto
mesh_terms: D001480:Basal Ganglia Diseases / Q000150:complications* / Q000532:radiotherapy; D001932:Brain Neoplasms / Q000150:complications* / Q000532:radiotherapy; D002648:Child; D004421:Dystonia / Q000209:etiology*; D006801:Humans; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000150:complications* / Q000532:radiotherapy