Neuropathy due to podophyllin intoxication.
A 22-year-old man developed a severe sensorimotor neuropathy following ingestion of podophyllin, which had been prescribed for genital condylomata. The initial toxic symptoms were vomiting and diarrhoea, followed by peripheral neuropathy. The neuropathy was still present 18 months later. Nerve conduction studies and sural nerve biopsy confirmed the presence of axonal degeneration.
O'Mahony
S
S
Department of Medicine, Cork Regional Hospital, Wilton, Ireland.
Keohane
C
C
Jacobs
J
J
O'Riordain
D
D
Whelton
M
M
D000328:Adult; D001369:Axons / Q000473:pathology; D001706:Biopsy; D003218:Condylomata Acuminata / Q000188:drug therapy; D006801:Humans; D008297:Male; D009410:Nerve Degeneration / Q000502:physiology; D009431:Neural Conduction / Q000502:physiology; D010412:Penile Neoplasms / Q000188:drug therapy; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000473:pathology / Q000503:physiopathology; D011033:Podophyllin / Q000506:poisoning* / Q000627:therapeutic use; D013497:Sural Nerve / Q000473:pathology
D011033:Podophyllin