title: Cytomegalovirus in a macerated second trimester fetus: persistent viral inclusions on light and electron microscopy.
abstract: The macerated stillborn fetus represents at least one third of all perinatal deaths. Microscopic examination of these specimens is often unrewarding. We have reported a clinically unsuspected cytomegalovirus infection in a second trimester macerated fetus. Cells suggestive of CMV inclusions were identified by light microscopy, but electron microscopy confirmed the presence of viral infection and proved valuable in making the diagnosis even though necrosis was severe.
authors.affiliation: Department of Pathology, Emory University School of Medicine, Atlanta, Ga.
authors.forename: D A
authors.initials: DA
authors.lastname: Schwartz
authors.forename: B
authors.initials: B
authors.lastname: Walker
authors.forename: B
authors.initials: B
authors.lastname: Furlong
authors.forename: E
authors.initials: E
authors.lastname: Breding
authors.forename: A
authors.initials: A
authors.lastname: Someren
mesh_terms: D000022:Abortion, Spontaneous / Q000209:etiology* / Q000382:microbiology; D000293:Adolescent; D003587:Cytomegalovirus / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000150:complications*; D005260:Female; D005313:Fetal Death / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D006801:Humans; D007181:Inclusion Bodies, Viral / Q000648:ultrastructure*; D008854:Microscopy, Electron; D009336:Necrosis; D011247:Pregnancy; D011262:Pregnancy Trimester, Second