5-Methylated naloxone, naltrexone, oxymorphone, and their 14-O-methyl ethers.
Schmidhammer
H
H
Institute of Organic and Pharmaceutical Chemistry, University of Innsbruck, Austria.
Leander
J D
JD
Mayer-Valkanover
K
K
Nussbaumer
C
C
Schmidt
C
C
Schoepp
D D
DD
Schratz
A
A
Walla-Kugler
M
M
D000818:Animals; D004987:Ethers; D066298:In Vitro Techniques; D008745:Methylation; D009270:Naloxone / Q000031:analogs & derivatives / Q000378:metabolism / Q000494:pharmacology; D009271:Naltrexone / Q000031:analogs & derivatives / Q000378:metabolism / Q000494:pharmacology; D009292:Narcotic Antagonists / Q000378:metabolism / Q000494:pharmacology*; D010111:Oxymorphone / Q000031:analogs & derivatives / Q000378:metabolism / Q000494:pharmacology; D000644:Quaternary Ammonium Compounds; D011957:Receptors, Opioid / Q000187:drug effects* / Q000378:metabolism; D013329:Structure-Activity Relationship
D004987:Ethers; D009292:Narcotic Antagonists; D000644:Quaternary Ammonium Compounds; D011957:Receptors, Opioid; C032257:methylnaltrexone; D009270:Naloxone; D009271:Naltrexone; D010111:Oxymorphone