title: Fetal cytomegalovirus infection: a case report.
abstract: Congenital cytomegalovirus infection is the most common perinatal infection. We describe a case of primary maternal cytomegalovirus infection during pregnancy and the prenatal diagnosis of fetal cytomegalovirus infection. Diagnosis was accomplished with percutaneous umbilical blood sampling. The fetal blood was evaluated with viral cultures, cytomegalovirus serologic testing, and nonspecific indicators of infection. Amniotic fluid was also cultured. All cultures were positive, which confirmed fetal infection. The pregnancy was terminated. Autopsy findings were consistent with fetal infection. The significance and utility of prenatal diagnosis are discussed.
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Science, Mount Sinai Medical Center, New York, NY 10029.
authors.forename: R L
authors.initials: RL
authors.lastname: Meisel
authors.forename: M
authors.initials: M
authors.lastname: Alvarez
authors.forename: L
authors.initials: L
authors.lastname: Lynch
authors.forename: U
authors.initials: U
authors.lastname: Chitkara
authors.forename: D J
authors.initials: DJ
authors.lastname: Emanuel
authors.forename: R L
authors.initials: RL
authors.lastname: Berkowitz
mesh_terms: D000028:Abortion, Induced; D000328:Adult; D000653:Amniotic Fluid / Q000382:microbiology; D001769:Blood / Q000382:microbiology; D003586:Cytomegalovirus Infections / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D011247:Pregnancy; D011296:Prenatal Diagnosis