Recovery of hepatitis A virus from a water supply responsible for a common source outbreak of hepatitis A.
An outbreak of hepatitis A occurred in a north Georgia trailer park served by a private well. Of 18 residents who were serosusceptible to hepatitis A virus (HAV), 16 (89%) developed hepatitis A. Well water samples were collected 3 months after illness onset in the index case and 28 days after illness onset in the last trailer park resident. Hepatitis A virus antigen (HAVAg) was detected in the samples by enzyme immunoassay from three of the five cell lines following two 30-day passages and from a fourth cell line following a third passage of 21 days.
Bloch
A B
AB
Office of Epidemiology, Georgia Department of Human Resources, Atlanta 30309.
Stramer
S L
SL
Smith
J D
JD
Margolis
H S
HS
Fields
H A
HA
McKinley
T W
TW
Gerba
C P
CP
Maynard
J E
JE
Sikes
R K
RK
D000328:Adult; D000956:Antigens, Viral / Q000302:isolation & purification; D002478:Cells, Cultured; D004196:Disease Outbreaks; D004812:Epidemiologic Methods; D005845:Georgia; D006506:Hepatitis A / Q000453:epidemiology*; D035921:Hepatitis A Antigens; D006507:Hepatovirus / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D014776:Virus Cultivation; D014871:Water Microbiology; D014881:Water Supply
D000956:Antigens, Viral; D035921:Hepatitis A Antigens