[The reliability of fine needle aspiration cytology in the diagnosis of breast cancer].
Between September 1981 and December 1987, 1023 palpable breast tumors were submitted for cytological evaluation by fine needle aspiration before surgery (carcinoma: 793 cases, benign breast diseases: 230 cases). Clinical factor relating to the success of the aspirations were evaluated. Cases were regarded as positive when patients had a grade IV or more rating by Papanicolaou classification. The sensitivity was shown to be 73% (578/793); the specificity being 98% (226/230). A significantly lower rate of positive cancer identification occurred in smaller tumors (less than 2 cm, P less than 0.01) or scirrhous carcinomas (P less than 0.05). The comparison of positive rates between the aspiration cytology (66%) and the stamp cytology (95%) in 258 breast cancers (P less than 0.01) indicates the limited value of cytological diagnosis of breast cancers by fine needle aspiration.
Hisamatsu
K
K
Dept. of Breast Surgery, Kyushu Cancer Center Hospital.
Nomura
Y
Y
Tashiro
H
H
Katsuta
Y
Y
Hayashi
I
I
Sonoda
F
F
D002293:Adenocarcinoma, Scirrhous / Q000175:diagnosis / Q000473:pathology; D001707:Biopsy, Needle / Q000379:methods; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000175:diagnosis / Q000473:pathology; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D011237:Predictive Value of Tests