[Small cell lung carcinoma. Value of the evaluation of extension for the therapeutic strategy].
Small-cell lung carcinoma can be distinguished from other histological types of lung cancer because of its high metastatic potential. Initial staging procedures divide the patients into two main prognostic groups: the so-called "limited" (to the thorax) and the extensive disease patients. Based on the results of a prospective pilot study involving 182 patients and on a review of the literature, the authors discuss the usefulness of initial staging in increasing the number of detectable metastases, assessing tumour burden, evaluating treatment results and identifying prognostic factors. Complete tumour staging at the time of diagnosis appears to be very helpful for a better knowledge of the disease and better therapeutic decisions.
Trillet
V
V
Service de Pneumologie, Hôpital Louis-Pradel, Lyon.
Chauvin
F
F
Champel
F
F
Bernard
J P
JP
Brune
J
J
Clavel
M
M
Cordier
J F
JF
Emonot
A
A
Guérin
J C
JC
Kalb
J C
JC
D000310:Adrenal Gland Neoplasms / Q000188:drug therapy / Q000556:secondary; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D018288:Carcinoma, Small Cell / Q000188:drug therapy / Q000473:pathology*; D002986:Clinical Trials as Topic; D003131:Combined Modality Therapy; D004317:Doxorubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary; D008175:Lung Neoplasms / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D009367:Neoplasm Staging; D011379:Prognosis; D011446:Prospective Studies; D013120:Spinal Cord Neoplasms / Q000188:drug therapy / Q000556:secondary
D005047:Etoposide; D004317:Doxorubicin; D007069:Ifosfamide
Cancer bronchique à petites cellules. Intérêt du bilan d'extension dans la stratégie thérapeutique.