title: Role of noradrenaline in behavioral changes after defeat in male and female rats.
abstract: We have tested the effect of noradrenaline depletion by clonidine in agonistic behavior of intact male and gonadectomized testosterone-treated female rats. Animals were subjected to the 'resident-intruder' paradigm: in 4 consecutive daily confrontations residents defeated intruders. Clonidine-treated intruder males showed higher levels of aggression than did their saline-injected controls. In contrast, in females, in which defeat was also followed by reduction of aggression, no effect of clonidine treatment was found.
authors.affiliation: The Netherlands Institute for Brain Research, Amsterdam.
authors.forename: J
authors.initials: J
authors.lastname: Scholtens
authors.forename: M
authors.initials: M
authors.lastname: Roozen
authors.forename: M
authors.initials: M
authors.lastname: Mirmiran
authors.forename: N E
authors.initials: NE
authors.lastname: van de Poll
mesh_terms: D000374:Aggression / Q000502:physiology*; D000378:Agonistic Behavior / Q000502:physiology*; D000818:Animals; D001921:Brain / Q000502:physiology; D004291:Dominance-Subordination; D005260:Female; D008297:Male; D009638:Norepinephrine / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D011941:Receptors, Adrenergic / Q000502:physiology; D012737:Sex Factors; D012930:Social Dominance; D013739:Testosterone / Q000502:physiology
chemical_list: D011941:Receptors, Adrenergic; D013739:Testosterone; D009638:Norepinephrine