[Sterility from hormonal causes and unexplained sterility. Treatment with cyclofenil. Double-blind controlled study].
We treated 213 women during 3 cycles by cyclofenil versus placebo in a double-blind study. These women had infertility caused by ovulatory deficiencies, a cervical factor or idiopathic infertility. Twenty-six of the 114 women receiving cyclofenil became pregnant and 21 of the 99 receiving the placebo. The cumulative pregnancy rates were identical in the 2 groups: 22 per cent in 3 cycles. The authors insist on the importance of a good doctor-patient relationship and the role of the placebo effect in any treatment of infertility.
Cabau
A
A
Krulik
D
D
Reboul
J
J
D000328:Adult; D002986:Clinical Trials as Topic; D003408:Cresols / Q000627:therapeutic use*; D003506:Cyclofenil / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy / Q000209:etiology*; D010817:Physician-Patient Relations; D011247:Pregnancy / Q000502:physiology*
D003408:Cresols; D003506:Cyclofenil
Stérilités de cause hormonale et stérilités inexpliquées. Traitement par le cyclofénil. Etude contrôlée à double insu.