title: Deduced amino acid sequence of bovine aromatic L-amino acid decarboxylase: homology to other decarboxylases.
abstract: Nucleotide sequence of cDNA for bovine aromatic L-amino acid decarboxylase (AADC) was analyzed. The deduced amino acid sequence of bovine AADC shows 57% identity to drosophila AADC and 37% to plant Catharanthus roseus AADC. The 7-amino acid sequence of the pyridoxal phosphate binding site is completely conserved among drosophila, pig and bovine AADC. AADC primary structure also shows high homology to that of feline glutamic acid decarboxylase.
authors.affiliation: Laboratory of Molecular Neurobiology, Burke Rehabilitation Center, Cornell University Medical College, White Plains, NY 10605.
authors.forename: U J
authors.initials: UJ
authors.lastname: Kang
authors.forename: T H
authors.initials: TH
authors.lastname: Joh
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001142:Aromatic-L-Amino-Acid Decarboxylases / Q000235:genetics*; D001483:Base Sequence; D004330:Drosophila; D008969:Molecular Sequence Data; D010944:Plants; D012689:Sequence Homology, Nucleic Acid
chemical_list: D001142:Aromatic-L-Amino-Acid Decarboxylases