title: Observations on the treatment of allergic rhinitis with the method of invigorating vital energy and strengthening the body surface resistance.
abstract: From clinical practice, the authors concluded that the principal pathogenic factor in allergic rhinitis is deficient resistance of the body surface, and the patient is exposed to invasion of wind-evil. 495 cases of the allergic rhinitis have been treated with the method of invigorating vital energy and strengthening the body surface resistance (Bu Qi Gu Biao); the total effective rate was 84%, and the recurrence rate was 13.2% in a follow-up of 2 years. The changes in plasma cyclic nucleotides of the patients, and the ultrastructure of nasal mucosa of patients and animal models were also observed before and after treatment. The results showed that the TCM therapy tended to normalize the plasma cyclic nucleotide level, to improve the morphology and function of cells and organelles, to restore the function of mucosal cilia, to reduce the infiltration of eosinophils and their degranulation, to reduce tissue edema, and to eliminate the deposit of immune complexes.
authors.affiliation: E.N.T. Department of Combined TCM and Western Medicine, Tianjin.
authors.forename: W
authors.initials: W
authors.lastname: Lin
authors.forename: Z
authors.initials: Z
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D002648:Child; D000242:Cyclic AMP / Q000378:metabolism; D006152:Cyclic GMP / Q000378:metabolism; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000648:ultrastructure; D011817:Rabbits; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy* / Q000378:metabolism; D006255:Rhinitis, Allergic, Seasonal / Q000188:drug therapy* / Q000378:metabolism
chemical_list: D004365:Drugs, Chinese Herbal; D000242:Cyclic AMP; D006152:Cyclic GMP