title: [The receptor binding of 3H-corticosterone and the dopamine content in the striatum of rats with a predisposition to audiogenic seizures].
abstract: The reactivity of hypophyseal-adrenocortical system, the receptor binding of 3H-corticosterone, and the catecholamines content in cerebral monoaminergic structures were studied in the Krushinskiĭ-Molodkina rats predisposed to audiogenic seizures and in control Wistar rats. No significant linear differences were found in these parameters in conditions of normal living activity. The hypophyseal-adrenocortical system of the Krushinskiĭ-Molodkina rats proved to be more responsive to auditory action. These animals revealed a higher dopamine content and a higher receptor binding of 3H-corticosterone in the striatum as compared with Wistar rats. The catecholamines and corticosteroids seem to interact in the process of regulation of the hypophyseal-adrenocortical system reactivity and of the function of nigrostriatal system when performing the organism response to a stimulus.
authors.forename: V V
authors.initials: VV
authors.lastname: Rakitskaia
authors.forename: I A
authors.initials: IA
authors.lastname: Garina
authors.forename: N G
authors.initials: NG
authors.lastname: Lopatina
authors.forename: S G
authors.initials: SG
authors.lastname: Pivina
authors.forename: V G
authors.initials: VG
authors.lastname: Shaliapina
mesh_terms: D000161:Acoustic Stimulation; D000818:Animals; D003342:Corpus Striatum / Q000378:metabolism*; D003345:Corticosterone / Q000378:metabolism*; D004198:Disease Susceptibility / Q000378:metabolism; D004298:Dopamine / Q000378:metabolism*; D009638:Norepinephrine / Q000378:metabolism; D010913:Pituitary-Adrenal System / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains; D011965:Receptors, Glucocorticoid / Q000378:metabolism*; D011987:Receptors, Steroid; D012640:Seizures / Q000378:metabolism*; D014316:Tritium
chemical_list: D011965:Receptors, Glucocorticoid; D011987:Receptors, Steroid; C024357:corticosterone receptor; D014316:Tritium; D004298:Dopamine; D003345:Corticosterone; D009638:Norepinephrine
vernacular_title: Retseptornoe sviazyvanie 3H-kortikosterona i soderzhanie dofamina v striatume krys s predraspolozhennost'iu k audiogennym sudorogam.