[Drug-induced esophagitis and its complications. Retrospective study of 30 case reports and review of 650 published cases (1970-1987)].
Prevalence and incidence of drug-related esophagitis are probably underestimated. The condition can often be diagnosed on the basis of history alone. Tetracyclines and emepronium bromide were implicated in most published cases. Endoscopy usually shows erosions in the upper two thirds of the esophagus. These esophageal lesions generally heal after the medication has been stopped. Complications such as stricture, hemorrhage or perforation are very rare.
Ollyo
J B
JB
Division de gastro-entérologie, CHUV/PMU, Lausanne.
Fontolliet
C
C
Monnier
P
P
Wellinger
J
J
Restellini
A
A
Gonvers
J J
JJ
Savary
M
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D064420:Drug-Related Side Effects and Adverse Reactions; D004629:Emepronium / Q000009:adverse effects; D004941:Esophagitis / Q000139:chemically induced* / Q000175:diagnosis / Q000453:epidemiology; D004945:Esophagoscopy; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D013557:Switzerland / Q000453:epidemiology; D013752:Tetracycline / Q000009:adverse effects
D004629:Emepronium; D013752:Tetracycline
L'oesophagite médicamenteuse et ses complications. Etude rétrospective de 30 observations et revue de 650 cas publiés (1970-1987).