Evidence that the sheep associated form of malignant catarrhal fever is caused by a herpes virus.
Out of a cow, which was infected with the sheep form of malignant catarrhal fever (MCF), blood and spleen samples were inoculated into rabbits. From the spleen cells of an infected rabbit, which were cocultivated with bovine embryonic gingiva cells, a herpesvirus could be isolated. The isolate showed crossreactions with reference sera against the strain WC 11 (wildebeest form) in the SNT. An immunosuppressed heifer, which was infected with the isolate, contracted typical clinical symptoms of MCF. The isolate was named No. 732.
Schuller
W
W
Bundesanstalt für Virusseuchenbekämpfung bei Haustieren, Wien-Hetzendorf, Austria.
Cerny-Reiterer
S
S
Silber
R
R
D000818:Animals; D002417:Cattle; D005260:Female; D006564:Herpesviridae / Q000302:isolation & purification*; D006566:Herpesviridae Infections / Q000382:microbiology / Q000662:veterinary*; D008304:Malignant Catarrh / Q000382:microbiology*; D008854:Microscopy, Electron; D011817:Rabbits; D012756:Sheep; D014771:Virion / Q000302:isolation & purification