title: Sonographic patterns of the affected spleen in malignant lymphoma.
abstract: Sonographic examination showed spleen involvement in 43 patients with histological evidence of malignant lymphoma. In 23% of these cases the spleen was of normal size and 77% exhibited variable splenomegaly. Focal lesions could be seen in 27 patients, 16 exhibiting diffuse, small-nodule transformation of the sonographic parenchymal texture. Hodgkin lymphomas caused both focal (7 of 16) and diffuse (9 of 16), splenic lesions. All non-Hodgkin lymphomas of high-grade malignancy exhibited focal lesions, which are larger than 3 cm in diameter in 11 out of 13 patients. In non-Hodgkin lymphomas of low-grade malignancy, focal sites and diffuse destruction of splenic tissue texture were found, lesions of under 3 cm in diameter (11 of 13) being characteristic of this subtype.
authors.affiliation: Department of Medicine, Philipps University School of Medicine, Marburg, Federal Republic of Germany.
authors.forename: C
authors.initials: C
authors.lastname: Goerg
authors.forename: W B
authors.initials: WB
authors.lastname: Schwerk
authors.forename: K
authors.initials: K
authors.lastname: Goerg
authors.forename: K
authors.initials: K
authors.lastname: Havemann
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D013160:Splenic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D014463:Ultrasonography