What can a woman do about her risk of dying of breast cancer?
Every day, American women are told that one in ten will develop breast cancer, and some groups perceive their risk to be so high as to justify immediate bilateral mastectomy. Many associations with breast cancer have been identified, including a history of benign breast diseases, in situ carcinoma, a family history of breast cancer, prolonged menstruation as a result of early menarche or delayed menopause, few or late pregnancies, excessive alcohol intake, obesity, and possibly the use of estrogens as oral contraceptives or postmenopausal replacement therapy. In spite of these associations, our understanding of either the cause(s) of breast cancer or the sequence of events leading to a diagnosis of breast cancer is still inadequate to make global public health recommendations regarding life style--or even to initiate well-designed studies. The epidemiologic evidence strongly suggests, however, that events relatively early in a woman's life are more important than later events, even though most of the risk of developing breast cancer will be expressed after the age of 75. Possibly one of the greatest contributions we can make to our patients' welfare is to share the knowledge that the risk of dying of breast cancer is considerably smaller than the risk of developing breast cancer; that the risk of early death from breast cancer rarely exceeds 10% in even the highest risk groups; and that the life styles most likely to reduce the risk of cardiovascular disease and other scourges of womankind are also those most likely to reduce the risk of developing breast cancer.
Henderson
I C
IC
Harvard Medical School, Dana-Farber Cancer Institute, Boston, Massachusetts.
D001943:Breast Neoplasms / Q000453:epidemiology*; D002278:Carcinoma in Situ / Q000453:epidemiology*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008019:Life Style; D012307:Risk Factors; D014481:United States / Q000453:epidemiology