[Endocrine-metabolic relations in rats with genetic arterial hypertension].
Levels of triiodothyronine, thyroxine, insulin, glucose and free fatty acids in the blood; contents of adrenaline, noradrenaline in adrenals and glycogen in the liver; activity of phenylethanolamine-N-methyltransferase in adrenals, hexokinase and glucose-6-phosphatase in the liver were studied in male Wistar rats and rats with inherited stress-induced arterial hypertension /ISIAH/. It was found that genetically caused rise of hypophyseal-thyroid systems activity in ISIAH-rats leads to a decrease of insulin blood level, activation of lipolysis and breach of glucose tolerance.
Shorin
Iu P
IuP
Markel'
A L
AL
Seliatitskaia
V G
VG
Pal'chikova
N A
NA
Grinberg
P M
PM
Amstislavskiĭ
S Ia
SIa
D000311:Adrenal Glands / Q000032:analysis / Q000201:enzymology; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D004837:Epinephrine / Q000032:analysis; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005952:Glucose-6-Phosphatase / Q000032:analysis; D006593:Hexokinase / Q000032:analysis; D006973:Hypertension / Q000097:blood / Q000378:metabolism / Q000503:physiopathology*; D007328:Insulin / Q000097:blood; D008099:Liver / Q000201:enzymology; D008112:Liver Glycogen / Q000032:analysis; D008297:Male; D009638:Norepinephrine / Q000032:analysis; D010625:Phenylethanolamine N-Methyltransferase / Q000032:analysis; D051381:Rats; D011918:Rats, Inbred SHR; D011919:Rats, Inbred Strains; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D007328:Insulin; D008112:Liver Glycogen; D014284:Triiodothyronine; D010625:Phenylethanolamine N-Methyltransferase; D006593:Hexokinase; D005952:Glucose-6-Phosphatase; D013974:Thyroxine; D009638:Norepinephrine; D004837:Epinephrine
Endokrinno-metabolicheskie otnosheniia u kryss geneticheski obuslovlennoĭ arterial'noĭ gipertenzieĭ.