Modulation of rat Kupffer cells on high density lipoprotein receptors on hepatocytes.
The present study found that conditioned media from Kupffer cells preincubated with acetylated LDL or acetylated LDL and zymosan increased the number of HDL receptors on hepatocytes, using the method of conditioned media transfer. This indicated that the transferable factors produced by Kupffer cells modulate HDL receptors on hepatocytes.
He
Z G
ZG
Department of Pathophysiology, Nanjing Medical College, PRC.
Cai
H J
HJ
Chen
X Y
XY
Wang
N
N
D000818:Animals; D002352:Carrier Proteins; D002478:Cells, Cultured; D003470:Culture Media; D007728:Kupffer Cells / Q000502:physiology*; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL / Q000494:pharmacology; D008099:Liver / Q000166:cytology*; D008297:Male; D016601:RNA-Binding Proteins; D051381:Rats; D011919:Rats, Inbred Strains; D011956:Receptors, Cell Surface / Q000378:metabolism*; D018110:Receptors, Lipoprotein; D015054:Zymosan / Q000494:pharmacology
D002352:Carrier Proteins; D003470:Culture Media; D008075:Lipoproteins, HDL; D008077:Lipoproteins, LDL; D016601:RNA-Binding Proteins; D011956:Receptors, Cell Surface; D018110:Receptors, Lipoprotein; C031616:high density lipoprotein receptors; C075197:high density lipoprotein binding protein; D015054:Zymosan