[Interstitial pneumonia developed after combination chemotherapy with (CDDP, VDS, MMC) and radiotherapy].
Reported is a case of interstitial pneumonia that developed after CDDP, VDS, and MMC combination chemotherapy and radiotherapy. The patient, a 68-year-old male, had received chemotherapy three times, beginning with CDDP + VDS, followed by CDDP, VDS, and MMC, in that sequence, after which he was given radiotherapy. The interstitial pneumonia developed one day after a dose of 54 Gy. It is felt that MMC played the leading role and the radiation the inducing role in the development of his interstitial pneumonia.
Koga
K
K
Dept. of Radiation, National Miyazaki Hospital.
Minoda
S
S
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D018288:Carcinoma, Small Cell / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D002945:Cisplatin / Q000008:administration & dosage / Q000009:adverse effects; D003131:Combined Modality Therapy; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D008297:Male; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage / Q000009:adverse effects; D011658:Pulmonary Fibrosis / Q000139:chemically induced / Q000209:etiology*; D011832:Radiation Injuries / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects*; D014751:Vindesine / Q000008:administration & dosage / Q000009:adverse effects
D008937:Mitomycins; D016685:Mitomycin; D002945:Cisplatin; D014751:Vindesine