Human papillomaviruses and upper airway oncogenesis.
This review summarizes the relationship between human papillomaviruses (HPVs) and upper airway tumors. The epidemiology of HPV in benign and malignant tumors, the life cycle of the virus, the effects of the virus on laryngeal papillomas, possible mechanisms of malignant conversion, and the molecular biology of the virus are described.
Steinberg
B M
BM
Department of Otolaryngology, Long Island Jewish Medical Center, New Hyde Park, NY 11042.
D006801:Humans; D027383:Papillomaviridae / Q000235:genetics / Q000254:growth & development; D012142:Respiratory Tract Neoplasms / Q000382:microbiology*; D014158:Transcription, Genetic; D014412:Tumor Virus Infections