Relationship between cAMP concentration in anterior hypothalamic-preoptic region and the ultradian wake-sleep cycle.
In the rat anterior hypothalamic-preoptic region adenosine 3':5'-cyclic monophosphate concentration changes during the ultradian wake-sleep cycle. The administration of DL-propranolol and the exposure to low ambient temperature decreased the nucleotide concentration and also modified the wake-sleep cycle. This suggests that in this region a biochemical correlation exists with different functional states.
Amici
R
R
Istituto di Fisiologia umana, Università di Bologna, Italy.
Fadiga
L
L
Perez
E
E
Zamboni
G
G
Parmeggiani
P L
PL
D000204:Activity Cycles / Q000187:drug effects; D000818:Animals; D000242:Cyclic AMP / Q000378:metabolism*; D007032:Hypothalamus, Anterior / Q000187:drug effects / Q000502:physiology*; D008297:Male; D011301:Preoptic Area / Q000187:drug effects / Q000502:physiology*; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D011919:Rats, Inbred Strains; D012016:Reference Values; D012890:Sleep / Q000187:drug effects; D013696:Temperature; D014851:Wakefulness / Q000187:drug effects
D011433:Propranolol; D000242:Cyclic AMP