title: [Seroprevalence of human parvovirus B 19 antibodies (Sticker's disease/erythema infectiosum) in the DRG population].
abstract: We tested 638 human sera of all age groups (patients and blood donors) from the northern area of the G.D.R. and found 216 cases (33.9%) of specific parvovirus B19 antibodies (IgG) by antibody capture ELISA. The seroprevalence rose to 36.7% when the 18 parvo B19-IgM- and/or parvo B19-DNA-positive results were included. The antibody prevalence was 24.9 (27.8% resp.) in the 0-10 years group and increased continuously in the following age groups up to 61.1% (69.4% resp.) in the 51-60 years group. 50% of the newborn infants showed parvo B19-IgG-antibodies in the cord blood (of maternal origin). No sex differences in seroprevalence were observed. Parvovirus B19 is obviously very prevalent in the G.D.R. population. The main immunization occurs in the first 30-40 years of life but infection with parvo B19 at a later age is also well documented. Hence it follows that 35-45% of all G.D.R. females of reproductive age are susceptible to a parvovirus B19 infection.
authors.affiliation: Klinik für Kindermedizin, Ernst-Moritz-Arndt-Universität Greifswald.
authors.forename: S
authors.initials: S
authors.lastname: Wiersbitzky
authors.forename: T F
authors.initials: TF
authors.lastname: Schwarz
authors.forename: R
authors.initials: R
authors.lastname: Bruns
authors.forename: G
authors.initials: G
authors.lastname: Jäger
authors.forename: S
authors.initials: S
authors.lastname: Bittner
authors.forename: H
authors.initials: H
authors.lastname: Weidemann
authors.forename: F
authors.initials: F
authors.lastname: Deinhardt
authors.forename: B
authors.initials: B
authors.lastname: Hottenträger
authors.forename: E
authors.initials: E
authors.lastname: Abel
authors.forename: L
authors.initials: L
authors.lastname: Ladstätter
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000302:isolation & purification*; D002648:Child; D002675:Child, Preschool; D004890:Erythema / Q000276:immunology*; D005859:Germany, East / Q000453:epidemiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008875:Middle Aged; D010321:Parvoviridae / Q000276:immunology*; D010322:Parvoviridae Infections / Q000453:epidemiology / Q000276:immunology*; D011159:Population Surveillance
chemical_list: D000914:Antibodies, Viral
vernacular_title: Seroprävalenz von Antikörpern gegen das humane Parvovirus B 19 (Ringelröteln/Erythema infectiosum) in der DDR-Bevölkerung.