Efficacy and tolerability of a fixed combination of metoprolol CR/ZOK 100 mg and hydrochlorothiazide (HCT) 12.5 mg in comparison with the fixed combination of metoprolol and HCT.
Leikersfeldt
G
G
Frederiksberg Hospital, Denmark.
Rasmussen
S L
SL
Atmer
B
B
Hjalmers
S
S
Wahlqvist
I
I
D000328:Adult; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D003692:Delayed-Action Preparations; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D015444:Exercise; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D006852:Hydrochlorothiazide / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006973:Hypertension / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008790:Metoprolol / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008875:Middle Aged; D016032:Randomized Controlled Trials as Topic; D013607:Tablets
D003692:Delayed-Action Preparations; D013607:Tablets; D006852:Hydrochlorothiazide; D008790:Metoprolol