[Study of cellular immunity and the opioid peptide system in patients with multiple sclerosis].
Twenty-five patients with chronic progressing multiple sclerosis were examined for the content of beta-endorphin in blood serum, supernatants of activated lymphocytes and CSF by RIA. At the same time the parameters of cellular immunity were appraised. Different relations were discovered between cellular immunity and the content of beta-endorphin in biological fluids which may play a material part in the pathogenesis of multiple sclerosis.
Demina
T L
TL
Boĭko
A N
AN
Rossel's
A N
AN
Balashov
K E
KE
Popova
N F
NF
D000328:Adult; D002908:Chronic Disease; D003470:Culture Media; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D007376:Interleukin-2 / Q000032:analysis*; D007958:Leukocyte Count; D008213:Lymphocyte Activation / Q000187:drug effects / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000378:metabolism*; D010835:Phytohemagglutinins / Q000494:pharmacology; D013601:T-Lymphocytes / Q000276:immunology*; D001615:beta-Endorphin / Q000097:blood* / Q000134:cerebrospinal fluid
D003470:Culture Media; D007376:Interleukin-2; D010835:Phytohemagglutinins; D001615:beta-Endorphin
Issledovanie kletochnogo immuniteta i sistemy opiatnykh peptidov u bol'nykh rassiannym sklerozom.