title: Hypertension and renal failure in a patient with tuberous sclerosis.
abstract: The cause of hypertension in this patient with tuberous sclerosis appeared to be the result of volume expansion due to renal failure. Renal insufficiency was presumably caused by extensive replacement of renal parenchyma with angiomyolipomas, resulting in compression and distortion of the renal parenchyma. Noninvasive imaging techniques were the most useful for characterizing the extent of the disease. It is clearly important to monitor renal function and blood pressure of patients with tuberous sclerosis as they grow older.
authors.affiliation: Interinstitute Medical Genetics Program, Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, Md 20892.
authors.forename: J E
authors.initials: JE
authors.lastname: Green
authors.forename: G W
authors.initials: GW
authors.lastname: Adams
authors.forename: T H
authors.initials: TH
authors.lastname: Shawker
authors.forename: F L
authors.initials: FL
authors.lastname: Sax
authors.forename: D M
authors.initials: DM
authors.lastname: Koeller
authors.forename: M A
authors.initials: MA
authors.lastname: Zasloff
mesh_terms: D000328:Adult; D004452:Echocardiography; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000000981:diagnostic imaging / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed; D014402:Tuberous Sclerosis / Q000150:complications*; D014463:Ultrasonography