Pneumonia of lambs following inoculation of isolates of sheep herpesvirus (caprine herpesvirus 1) of different DNA genotypes.
One-day-old, specific pathogen-free lambs, were equally susceptible to infection with three isolates of caprine herpesvirus 1 (CHV1). One of these isolates was genomically different by DNA analysis. Lesions, which were confined to the lung, ranged from a mild interstitial reaction to widespread consolidation. CHV1 was recovered from lungs and less commonly from liver and adrenal gland. Three-week-old SPF lambs were also successfully infected with CHV1. Histopathological findings were similar to those in 1-week-old lambs.
Scott
F M
FM
Moredum Research Institute, Edinburgh, Scotland.
Angus
K W
KW
Dewar
P
P
D000818:Animals; D004247:DNA / Q000235:genetics*; D005838:Genotype; D006564:Herpesviridae / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D006566:Herpesviridae Infections / Q000382:microbiology / Q000662:veterinary*; D008168:Lung / Q000473:pathology; D011014:Pneumonia / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D012756:Sheep; D012757:Sheep Diseases / Q000382:microbiology*
D004247:DNA