title: [Calmodulin blockaders weaken the short-term plasticity of the neuronal cholinoreceptors in the edible snail].
abstract: By means of recording transmembrane ion currents of identified snail neurones PPa3 and LPa3 a reversible weakening was shown of the speed and depth of extinction of neuronal cholinoreceptor membrane reactions to repeated iontophoretic applications of acetylcholine to the soma by a number of calmodulin blockaders: R24571 (20-50 mmol/l), trifluoperazine (50-200 mmol/l), chlorpromazine (20-60 mmol/l) and prenylamine lactate (30-400 mmol/l). The obtained results testify to a positive control by calmodulin of short-term cholinoreceptors plasticity of the studied neurons.
authors.forename: A S
authors.initials: AS
authors.lastname: Pivovarov
authors.forename: E I
authors.initials: EI
authors.lastname: Drozdova
authors.forename: B I
authors.initials: BI
authors.lastname: Kotliar
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D002147:Calmodulin / Q000037:antagonists & inhibitors* / Q000502:physiology; D006372:Helix, Snails / Q000187:drug effects*; D066298:In Vitro Techniques; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D009473:Neuronal Plasticity / Q000187:drug effects* / Q000502:physiology; D009474:Neurons / Q000187:drug effects* / Q000502:physiology; D011950:Receptors, Cholinergic / Q000187:drug effects* / Q000502:physiology
chemical_list: D002147:Calmodulin; D011950:Receptors, Cholinergic; D000109:Acetylcholine
vernacular_title: Blokatory kal'modulina oslabliaiut kratkovremennuiu plastichnost' kholinoretseptorov neĭronov vinogradnoĭ ulitki.