Oral hairy leukoplakia in an HIV-seronegative heart transplant patient.
While oral hairy leukoplakia has been observed predominantly in patients with HIV-infection at various stages, recent reports have shown that HL may also occur in patients immunosuppressed for other reasons. This report describes oral hairy leukoplakia in a heart transplant recipient with negative HIV serology. The histopathologic diagnosis of HL was confirmed by immunohistochemical detection of EBV-VCA in the surface epithelium of the lesion and by negative staining electron microscopy.
Schmidt-Westhausen
A
A
Abteilung für zahnärztliche Chirurgie/Oralchirurgie, Nord, Freie Universität Berlin.
Gelderblom
H R
HR
Reichart
P A
PA
D000956:Antigens, Viral; D002180:Candidiasis, Oral / Q000150:complications; D002213:Capsid; D006679:HIV Seropositivity / Q000150:complications*; D016027:Heart Transplantation; D004854:Herpesvirus 4, Human / Q000276:immunology / Q000302:isolation & purification; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D007972:Leukoplakia, Oral / Q000150:complications / Q000209:etiology* / Q000382:microbiology; D008297:Male; D008875:Middle Aged
D000956:Antigens, Viral