[The functional characteristics of the reproductive system in women who are heterozygous carriers of 21-hydroxylase deficiency].
This paper reports the results of evaluation of reproductive histories of 52 heterozygous female carriers of 21-hydroxylase deficiency who gave birth to children with classic congenital adrenocortical hyperplasia. Functional ACTH adrenal tests of these women were compared with those in a control group of noncarriers. Test findings are discussed with respect to the pathogenesis of reproductive tract disorders in the carriers of a mutant gene.
Dzenis
I G
IG
Brykova
E K
EK
Bakharev
V A
VA
Fanchenko
N D
ND
Semenova
N V
NV
D000304:Adrenal Cortex Function Tests; D000305:Adrenal Cortex Hormones / Q000097:blood; D000312:Adrenal Hyperplasia, Congenital / Q000235:genetics; D000324:Adrenocorticotropic Hormone; D000328:Adult; D005260:Female; D005817:Genetic Counseling; D006579:Heterozygote; D006801:Humans; D012098:Reproduction / Q000235:genetics / Q000502:physiology*; D013997:Time Factors
D000305:Adrenal Cortex Hormones; D000324:Adrenocorticotropic Hormone
Osobennosti funktsii reproduktivnoĭ sistemy u zhenshchen--geterozigotnykh nositel'nits nedostatochnosti 21-gidroksilazy.