A new cellular function for peroxisomes related to oxygen free radicals?
Although in cell biology peroxisomes are still 'young' organelles, it is becoming increasingly clear that they are involved in important cellular functions. Recent results have indicated the presence of the metalloenzyme superoxide dismutase in peroxisomes and the production of superoxide free radicals (O2-) in these oxidative organelles. These findings, together with other experimental evidence, point towards the existence of new roles for peroxisomes in cellular active oxygen metabolism, something that has a potential impact in multiple areas of cell biology, particularly in biochemistry and biomedicine.
del Río
L A
LA
Unidad de Bioquímica Vegetal, Estación Experimental del Zaidin, C.S.I.C., Granada, Spain.
Sandalio
L M
LM
Palma
J M
JM
D000818:Animals; D005609:Free Radicals; D008830:Microbodies / Q000201:enzymology / Q000378:metabolism / Q000502:physiology*; D010100:Oxygen / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000378:metabolism; D013481:Superoxides / Q000378:metabolism
D005609:Free Radicals; D013481:Superoxides; D013482:Superoxide Dismutase; D010100:Oxygen