title: Efficiency of phosphorylation of the cyclobut-G (A-69992) enantiomers by HSV-1 thymidine kinase does not correlate with their anti-herpesvirus activity.
authors.affiliation: Pharmaceutical Discovery, Abbott Laboratories, Abbott Park, IL 60064-3500.
authors.forename: W E
authors.initials: WE
authors.lastname: Kohlbrenner
authors.forename: C D
authors.initials: CD
authors.lastname: Carter
authors.forename: S W
authors.initials: SW
authors.lastname: Fesik
authors.forename: D W
authors.initials: DW
authors.lastname: Norbeck
authors.forename: J
authors.initials: J
authors.lastname: Erickson
mesh_terms: D000998:Antiviral Agents / Q000494:pharmacology*; D001711:Biotransformation; D006147:Guanine / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D010766:Phosphorylation; D018139:Simplexvirus / Q000187:drug effects* / Q000201:enzymology; D013237:Stereoisomerism; D013937:Thymidine Kinase / Q000494:pharmacology*
chemical_list: D000998:Antiviral Agents; D006147:Guanine; C063638:lobucavir; D013937:Thymidine Kinase