[Immunohistochemical study on distribution of human chorionic gonadotropin (HCG) and placental lactogen (HPL) in trophoblastic tumors].
Preliminary results of observation on the immunohistochemical localization of HCG and HPL are reported, involving totally 15 cases of hydatidiform moles, 17 cases of invasive moles and 15 cases of choriocarcinoma. An intermediate type of trophoblast (IT) was identified in the gestational trophoblastic tumors. The presence of HCG and HPL in both IT and syncytiotrophoblast (ST) varied with the type of trophoblastic tumors. Syncytiotrophoblast sometimes contained both of the hormones, whereas IT contained HPL predominantly. Cytotrophoblasts were devoid of HCG and HPL except in choriocarcinoma.
Wang
M Q
MQ
Department of Pathology, Shandong Medical University, Jinan.
D006063:Chorionic Gonadotropin / Q000378:metabolism*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D010928:Placental Lactogen / Q000378:metabolism*; D011247:Pregnancy; D014328:Trophoblastic Neoplasms / Q000378:metabolism*; D014327:Trophoblasts / Q000378:metabolism
D006063:Chorionic Gonadotropin; D010928:Placental Lactogen