Transcatheter hepatic segmental arterial embolization using lipiodol mixed with an anticancer drug and Gelfoam particles for hepatocellular carcinoma.
Transcatheter hepatic segmental arterial chemoembolization using Lipiodol mixed with an anticancer drug followed by the injection of Gelfoam particles, introduced into the tumor-bearing hepatic segment as the target area (segmental Lipiodol-TAE), was carried out in 54 patients with hepatocellular carcinoma (HCC), 7 of whom were later resected. In 5 of the resected 7 cases, complete necrosis was histologically verified. No death due to HCC was encountered in 47 nonoperated cases, and better therapeutic results were obtained with segmental Lipiodol-TAE. It was concluded that this technique does not adversely affect normal tissues, and it does reinforce the effect of TAE.
Uchida
H
H
Department of Radiology, Nara Medical University, Japan.
Ohishi
H
H
Matsuo
N
N
Nishimine
K
K
Ohue
S
S
Nishimura
Y
Y
Maeda
M
M
Yoshioka
T
T
D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D004317:Doxorubicin / Q000008:administration & dosage* / Q000627:therapeutic use; D004621:Embolization, Therapeutic; D005781:Gelatin Sponge, Absorbable; D006499:Hepatic Artery; D006801:Humans; D007459:Iodized Oil / Q000008:administration & dosage*; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D008875:Middle Aged
D007459:Iodized Oil; D004317:Doxorubicin