title: Reoxygenation injury and antioxidant protection: a tale of two paradoxes.
abstract: Under certain circumstances, added antioxidants can protect tissues against reoxygenation injury after ischemia. Yet reperfusing blood carries many antioxidants with it. The implications of this "antioxidant paradox" are discussed.
authors.affiliation: Molecular Toxicology, Oklahoma Medical Research Foundation, Oklahoma City 73104.
authors.forename: J M
authors.initials: JM
authors.lastname: Gutteridge
authors.forename: B
authors.initials: B
authors.lastname: Halliwell
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000378:metabolism* / Q000627:therapeutic use; D006801:Humans; D008954:Models, Biological; D015427:Reperfusion Injury / Q000188:drug therapy*; D013481:Superoxides / Q000378:metabolism
chemical_list: D000975:Antioxidants; D013481:Superoxides