title: Entry of pseudorabies virus into CHO cells is blocked at the level of penetration.
abstract: Replication of pseudorabies virus (PrV) in Chinese hamster ovary (CHO) cells, a cell line naturally resistant to infection by herpesviruses, is blocked at the level of penetration. Virions bound to the surface of CHO cells are taken up into cytoplasmic vesicles and degraded.
authors.affiliation: Institute for Clinical and Experimental Virology, Free University of Berlin, Federal Republic of Germany.
authors.forename: D
authors.initials: D
authors.lastname: Sawitzky
authors.forename: H
authors.initials: H
authors.lastname: Hampl
authors.forename: K O
authors.initials: KO
authors.lastname: Habermehl
mesh_terms: D000818:Animals; D002448:Cell Adhesion; D002460:Cell Line / Q000382:microbiology* / Q000648:ultrastructure; D002462:Cell Membrane / Q000382:microbiology; D006224:Cricetinae; D003412:Cricetulus; D003593:Cytoplasm / Q000382:microbiology; D006493:Heparin / Q000494:pharmacology; D011558:Herpesvirus 1, Suid / Q000502:physiology* / Q000648:ultrastructure; D008561:Membrane Fusion; D014779:Virus Replication / Q000187:drug effects
chemical_list: D006493:Heparin