title: [Early detection of scleroderma in quartz dust exposed workers and workers with silicosis by determining serum beta-galactosidase activity].
abstract: Progressive systemic sclerosis (PSS) is a rare disease belonging to the collagen diseases. PSS is frequently observed in workers with an intensive exposure to crystalline silica and with silicosis in the GDR. The recognition as an occupational disease is regulated by law. The elevated beta-galactosidase activity in the serum of patients with silicosis and beginning PSS can be used for detecting of early stages of PSS. References are given to medical care of patients with silicosis and exposure to quartz.
authors.affiliation: Arbeitshygienisches Zentrum Niederdorf.
authors.forename: J
authors.initials: J
authors.lastname: Mehlhorn
authors.forename: K
authors.initials: K
authors.lastname: Herrmann
authors.forename: H
authors.initials: H
authors.lastname: Täubig
authors.forename: B
authors.initials: B
authors.lastname: Döhler
authors.forename: V
authors.initials: V
authors.lastname: Ziegler
authors.forename: K
authors.initials: K
authors.lastname: Vietze
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004391:Dust / Q000009:adverse effects*; D005260:Female; D005696:Galactosidases / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000175:diagnosis* / Q000201:enzymology; D011791:Quartz / Q000009:adverse effects*; D012595:Scleroderma, Systemic / Q000175:diagnosis* / Q000201:enzymology; D012822:Silicon Dioxide / Q000009:adverse effects*; D012829:Silicosis / Q000150:complications*; D001616:beta-Galactosidase / Q000097:blood*
chemical_list: D004391:Dust; D011791:Quartz; D012822:Silicon Dioxide; D005696:Galactosidases; D001616:beta-Galactosidase
vernacular_title: Früherkennung der Sklerodermie bei Quarzstaubexponierten und Silikotikern durch Aktivitätsbestimmung der Serum-beta-Galaktosidase.