title: [Major and minor congenital anomalies in children with Wilms' tumor].
abstract: Wilms's tumour is a paediatric tumour of hereditary origin in 40% of cases. In children with Wilms's tumour associated congenital anomalies are frequent, particularly congenital anomalies of the kidney and urogenital tract. Over the period from 1972 to 1987 the authors carried out a prospective study and systematically investigated congenital major and minor anomalies in 24 children with Wilms's tumour. They revealed the presence of aniridia, bilateral cataract and cryptorchidism in 1/24 children, mental retardation, small stigated congenital major and minor anomalies in 40 chidism in 1/40 children, mental retardation, small stature and a cystic kidney in 1/40, mental retardation in 3/40. A detailed investigation of minor anomalies confirmed the presence of 2 to 3 anomalies in all observed children. Cytogenetic investigation was performed in all children. Only in a child with aniridia Wilms's tumour a cytogenetic anomaly, 11p deletion, was found.
authors.forename: D
authors.initials: D
authors.lastname: Skorić
authors.forename: E
authors.initials: E
authors.lastname: Stojimrović
authors.forename: D
authors.initials: D
authors.lastname: Paunović
authors.forename: G
authors.initials: G
authors.lastname: Bunjevacki
authors.forename: G
authors.initials: G
authors.lastname: Pusonjić
authors.forename: B
authors.initials: B
authors.lastname: Ljiljak
authors.forename: L
authors.initials: L
authors.lastname: Dokmanović
mesh_terms: D002648:Child; D000013:Congenital Abnormalities / Q000473:pathology; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications*; D011446:Prospective Studies; D009396:Wilms Tumor / Q000150:complications*
vernacular_title: Kongenitalne major i minor anomalije kod dece sa Wilm'sovim tumorom.