title: Isolation of multiple cytomegalovirus strains from a patient with adult T cell leukemia.
abstract: A 66-year-old male with adult T cell leukemia had an ulcer on the left medial thigh. The biopsy of the skin lesion revealed enlarged endothelial cells with acidophilic intranuclear inclusion bodies, suggesting cytomegalovirus (CMV) infection. At autopsy, CMV was isolated from a nodular skin lesion of the scrotum. The urine constantly tested positive for CMV. Restriction endonuclease cleavage analysis of DNA of the isolates from the skin and urine indicated that this patient was infected with two different strains of CMV.
authors.affiliation: Department of Microbiology, Miyazaki Medical College, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Eizuru
authors.forename: Y
authors.initials: Y
authors.lastname: Minamishima
authors.forename: M
authors.initials: M
authors.lastname: Hirose
authors.forename: K
authors.initials: K
authors.lastname: Ogata
authors.forename: A
authors.initials: A
authors.lastname: Tajiri
authors.forename: S
authors.initials: S
authors.lastname: Tada
authors.forename: S
authors.initials: S
authors.lastname: Inoue
authors.forename: K
authors.initials: K
authors.lastname: Kaketani
authors.forename: A
authors.initials: A
authors.lastname: Sumiyoshi
mesh_terms: D000368:Aged; D003587:Cytomegalovirus / Q000302:isolation & purification*; D003586:Cytomegalovirus Infections / Q000150:complications*; D004262:DNA Restriction Enzymes / Q000378:metabolism; D006801:Humans; D015458:Leukemia, T-Cell / Q000150:complications / Q000382:microbiology*; D008297:Male
chemical_list: D004262:DNA Restriction Enzymes