title: [Pathogenetic therapy of hemorrhagic strokes].
abstract: The authors provide grounds for the principles of pathogenic therapy aimed at posthemorrhagic cerebral vasospasm, proliferation-necrotic angiopathy with ensuing cerebral damage wherein free radical oxidation and antifibrinolytic therapy are of major importance. The efficiency of combined pathogenic therapy comprising antioxidants, chelators, cyclooxygenase inhibitors, calcium antagonists, barbiturate protectors, membrane-stabilizing and limiting antifibrinolytic hemostatic drugs is evaluated.
authors.forename: V M
authors.initials: VM
authors.lastname: Gabashvili
authors.forename: R R
authors.initials: RR
authors.lastname: Skakarishvili
authors.forename: M T
authors.initials: MT
authors.lastname: Dzhanelidze
authors.forename: T V
authors.initials: TV
authors.lastname: Dzhandzhgava
authors.forename: M G
authors.initials: MG
authors.lastname: Maruashvili
mesh_terms: D000933:Antifibrinolytic Agents / Q000008:administration & dosage; D000975:Antioxidants / Q000008:administration & dosage; D001921:Brain / Q000098:blood supply* / Q000378:metabolism; D002121:Calcium Channel Blockers / Q000008:administration & dosage; D002543:Cerebral Hemorrhage / Q000150:complications* / Q000188:drug therapy; D002544:Cerebral Infarction / Q000188:drug therapy* / Q000209:etiology / Q000378:metabolism; D016861:Cyclooxygenase Inhibitors; D004359:Drug Therapy, Combination; D005609:Free Radicals; D006490:Hemostatics / Q000008:administration & dosage; D006801:Humans; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism
chemical_list: D000933:Antifibrinolytic Agents; D000975:Antioxidants; D002121:Calcium Channel Blockers; D016861:Cyclooxygenase Inhibitors; D005609:Free Radicals; D006490:Hemostatics; D011451:Prostaglandin-Endoperoxide Synthases
vernacular_title: Patogeneticheskaia terapiia gemorragicheskikh insul'tov.