title: Cultivation of foot-and-mouth disease virus in BHK21 cells grown in microcarrier culture system.
abstract: When BHK21 cells were grown according to the microcarrier's system, they reached the highest concentration in 72 hrs. The infectivity of Foot-and-Mouth Disease (FMD) virus in BHK21 microcarrier culture increased 10 times compared with the conventional monolayer culture in rolling bottles.
authors.affiliation: Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia, Brescia, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Ferrari
authors.forename: M N
authors.initials: MN
authors.lastname: Losio
authors.forename: G L
authors.initials: GL
authors.lastname: Gualandi
authors.forename: M
authors.initials: M
authors.lastname: Bugnetti
mesh_terms: D000818:Animals; D005537:Aphthovirus / Q000254:growth & development*; D002460:Cell Line; D007700:Kinetics; D014776:Virus Cultivation