[The molecular epidemiology of poliomyelitis: the characteristics of the strains isolated from patients in Moscow in 1973-1986].
Eleven virus strains isolated from poliomyelitis patients in Moscow in 1973-1986 were analyzed by the method of oligonucleotide mapping of RNA. The genome of the isolates showed considerable similarity to the genomes of Sabin's vaccine strains and mainly to the vaccine strain of antigenic type 2. The conclusion was made that the sporadic cases of poliomyelitis registered in this region were etiologically linked with the vaccine strains of poliomyelitis virus. Only in one case the disease appeared in the recipient of the vaccine, in all other cases the patients were infected through contacts.
Kutitova
O K
OK
Lipskaia
G Iu
GIu
Maslova
S V
SV
Leshchinskaia
E V
EV
Martynenko
I N
IN
Koreshkova
G V
GV
Drozdov
S G
SG
Agol
V I
VI
D000914:Antibodies, Viral / Q000032:analysis; D001483:Base Sequence; D002675:Child, Preschool; D005243:Feces / Q000382:microbiology; D005814:Genes, Viral / Q000235:genetics; D006801:Humans; D007223:Infant; D008969:Molecular Sequence Data; D009031:Moscow / Q000453:epidemiology; D009841:Oligonucleotides / Q000235:genetics; D011051:Poliomyelitis / Q000453:epidemiology* / Q000382:microbiology; D017955:Poliovirus / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification; D012189:Retrospective Studies; D014505:Urban Population / Q000706:statistics & numerical data*
D000914:Antibodies, Viral; D009841:Oligonucleotides
Molekuliarnaia épidemiologiia poliomielita: kharakteristika shtammov, vydelennykh ot bol'nykh v Moskve v 1973-1986 gg.