[The experimental and clinical use of gelatin sponges with kanamycin and gentamycin for the prevention and treatment of suppurative complications in neurosurgery].
Antiseptic gelatin sponges with kanamycin and gentamicin, which were studied in experiments on animals and used in the clinic, are a reliable measure for the prevention of suppuration in craniocerebral surgery in planned operations and in combination with debridement in penetrating injury of the skull and brain. For therapeutic purposes, local application of the agents is effective in focal suppurative processes in the skull and brain after surgical debridement of the purulent focus (abscess of the brain, osteomyelitis of the skull, etc.).
Kharitonova
K I
KI
Rodiukova
E N
EN
Simonovich
A E
AE
Stupak
V V
VV
D000818:Animals; D000985:Antisepsis / Q000379:methods; D001921:Brain / Q000601:surgery*; D001927:Brain Diseases / Q000209:etiology / Q000517:prevention & control*; D001930:Brain Injuries / Q000150:complications / Q000601:surgery; D003692:Delayed-Action Preparations; D004285:Dogs; D004341:Drug Evaluation; D004353:Drug Evaluation, Preclinical; D005780:Gelatin; D005839:Gentamicins / Q000008:administration & dosage*; D006801:Humans; D007612:Kanamycin / Q000008:administration & dosage*; D011817:Rabbits; D013203:Staphylococcal Infections / Q000209:etiology / Q000517:prevention & control*; D013530:Surgical Wound Infection / Q000209:etiology / Q000517:prevention & control*; D014949:Wounds, Nonpenetrating / Q000150:complications / Q000601:surgery; D014950:Wounds, Penetrating / Q000150:complications / Q000601:surgery
D003692:Delayed-Action Preparations; D005839:Gentamicins; D007612:Kanamycin; D005780:Gelatin
Eksperimental'noe i klinicheskoe primenenie zhelatinovykh gubok s kanamitsinom i gentamitsinom dlia profilaktiki i lecheniia gnoĭnykh oslozhneniĭ v neĭrokhirurgii.