title: Signal transduction in bacteria.
abstract: Cells display a remarkable ability to respond to small fluctuations in their surroundings. In simple microbial systems, information from sensory receptors feeds into a circuitry of regulatory proteins that transfer high energy phosphoryl groups from histidine to aspartate side chains. This phosphotransfer network couples environmental signals to an array of response elements that control cell motility and regulate gene expression.
authors.affiliation: Department of Molecular Biology, Princeton University, New Jersey 08544.
authors.forename: J B
authors.initials: JB
authors.lastname: Stock
authors.forename: A M
authors.initials: AM
authors.lastname: Stock
authors.forename: J M
authors.initials: JM
authors.lastname: Mottonen
mesh_terms: D000595:Amino Acid Sequence; D001419:Bacteria / Q000235:genetics; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics; D018407:Bacterial Physiological Phenomena; D001426:Bacterial Proteins; D002633:Chemotaxis; D015964:Gene Expression Regulation, Bacterial; D008565:Membrane Proteins; D000072236:Methyl-Accepting Chemotaxis Proteins; D008969:Molecular Sequence Data; D009584:Nitrogen / Q000378:metabolism; D010750:Phosphoproteins; D018272:Porins; D015398:Signal Transduction
chemical_list: D001425:Bacterial Outer Membrane Proteins; D001426:Bacterial Proteins; D008565:Membrane Proteins; D000072236:Methyl-Accepting Chemotaxis Proteins; D010750:Phosphoproteins; D018272:Porins; D009584:Nitrogen