[The PIG-anchoring defect of lymphocyte populations in paroxysmal nocturnal hemoglobinuria].
Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by a defect expression of phosphatidylinositolglycan-(PIG-)linked surface molecules. This deficiency has been demonstrated for cells of myeloid origin so far, but not for lymphocytes. In these studies we examined the defect on lymphocyte subpopulations.
Schubert
J
J
Medizinische Hochschule Hannover, Abteilung Immunologie und Transfusionsmedizin.
Uciechowski
P
P
Delany
P
P
Schmidt
R E
RE
D005455:Fluorescent Antibody Technique; D017261:Glycosylphosphatidylinositols; D006457:Hemoglobinuria, Paroxysmal / Q000097:blood*; D006801:Humans; D008214:Lymphocytes / Q000473:pathology*; D010716:Phosphatidylinositols / Q000172:deficiency*; D011134:Polysaccharides / Q000172:deficiency*
D017261:Glycosylphosphatidylinositols; D010716:Phosphatidylinositols; D011134:Polysaccharides
Der PIG-Verankerungsdefekt auf Lymphozytenpopulationen bei paroxysmaler nächtlicher Hämoglobinurie.