title: [Cerebral and meningeal manifestations of AIDS: sensitivity of CT and T2-weighted MRT (129 patients)].
abstract: We studied 129 AIDS patients with suspected or proved intracranial manifestations of the disease. The purpose of this study was to compare the diagnostic sensitivity of unenhanced and contrast enhanced CT and unenhanced T2-weighted MR. In 35/129 patients CT and MR findings were normal. In 37/129 patients equivalent findings were obtained with both methods. Although CT and MR demonstrated intracranial pathology in 25 cases, MR was clearly superior. Six of these cases had solitary lesions in CT, while MR demonstrated multiple lesions. MR detected more foci than CT. In 24 patients with normal CT, MR detected intracranial manifestations of AIDS, namely solitary lesions in 8, multiple lesions in 12 and meningeal alterations in 4 patients. In only 8 patients with normal MR findings, CT revealed pathological contrast enhancement in 2 and parenchymal calcifications in 6 patients. Thus, in 20% of our patients MR but not CT was diagnostic. In another 20% MR provided additional diagnostic information. In conclusion, MR is recommended as the imaging modality of choice in AIDS patients with non-conclusive cranial CT.
authors.affiliation: Radiologische Klinik, Universitätsklinikum Rudolf Virchow/Standort, Charlottenburg.
authors.forename: H
authors.initials: H
authors.lastname: Henkes
authors.forename: W
authors.initials: W
authors.lastname: Schörner
authors.forename: R
authors.initials: R
authors.lastname: Jochens
authors.forename: P
authors.initials: P
authors.lastname: Lang
authors.forename: B
authors.initials: B
authors.lastname: Ruf
authors.forename: W
authors.initials: W
authors.lastname: Heise
authors.forename: M
authors.initials: M
authors.lastname: Trautmann
authors.forename: R
authors.initials: R
authors.lastname: Felix
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging; D000328:Adult; D002493:Central Nervous System Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology*; D005260:Female; D006801:Humans; D007968:Leukoencephalopathy, Progressive Multifocal / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed; D014123:Toxoplasmosis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000209:etiology
vernacular_title: Zerebrale und meningeale Manifestation des AIDS: Sensitivität von CT und T2-gewichteter MRT (129 Patienten).