[Evaluation of maximal Na K ATPase activity in the erythrocytes of patients with various types of arterial hypertension using the Na-23-NMR method].
The paper provides measurements of maximal Na+, K(+)-ATPase activity in 20 patients with hypertensive disease, 20 patients with secondary hypertension and 20 healthy donors. The investigation was made by high-resolution nuclear magnetic resonance using sodium nuclei. A significant decrease was found in Na+, K(+)-ATPase activity in the patients with hypertensive disease (9.0 +/- 0.3 mg-equiv. per lites cells an hour) as compared with those with secondary hypertension (10.3 +/- 0.3 mg-equiv. per liter cells an hour) and the controls (10.5 +/- 0.3 mg-equiv. per liter cells an hour), which supports the findings of impaired membrane morphology in hypertensive disease.
Revazov
A V
AV
Knubovets
T L
TL
Sibel'dina
L A
LA
Sumarokov
A V
AV
D000293:Adolescent; D000328:Adult; D000368:Aged; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000201:enzymology*; D006977:Hypertension, Renal / Q000201:enzymology*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase / Q000097:blood*
D012964:Sodium; D000254:Sodium-Potassium-Exchanging ATPase
Otsenka maksimal'noĭ aktivnosti Na+, K+ ATFazy v éritrotsitakh u bol'nykh s razlichnymi formami arterial'noĭ gipertenzii metodom 23Na-IaMR.