title: [The interactions of vitamins B1, B6 and B12 with non-steroidal antirheumatic and analgesic drugs: animal experiment results].
abstract: B-vitamins are therapeutically used in combination with nonsteroidal antiinflammatory drugs and weak analgesics. The animal experiments dealing with the antinociceptive and antiinflammatory activity of such combinations are reviewed with reference to the significance of the single vitamins B1, B6, and B12, the possible mechanisms of action, and the relevance of the animal data to man.
authors.affiliation: E. Merck, Biologische Forschung, Darmstadt.
authors.forename: G D
authors.initials: GD
authors.lastname: Bartoszyk
mesh_terms: D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D004357:Drug Synergism; D011736:Pyridoxine / Q000494:pharmacology*; D013831:Thiamine / Q000494:pharmacology*; D014805:Vitamin B 12 / Q000494:pharmacology*
chemical_list: D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D011736:Pyridoxine; D014805:Vitamin B 12; D013831:Thiamine
vernacular_title: Zur Wechselwirkung der Vitamine B1, B6 und B12 mit nichtsteroidalen Antirheumatika und Analgetika: Tierexperimentelle Befunde.