title: Rheumatologic manifestations of human parvovirus B19 infection in adults. Initial two-year clinical experience.
abstract: During 1987 and 1988, we identified 9 adults at the Medical and Rheumatology Services of the University of Iowa Hospitals and Clinics who had a clinical diagnosis of fifth disease; 8 of the 9 had symptoms of joint involvement. Another 12 adults with serologic positivity for anti-parvovirus B19 IgM antibody presented with polyarthralgia/polyarthritis. Patients were usually found to be seronegative for rheumatoid factor, and none developed nodules or erosive disease. Many patients with chronic disease met criteria for a diagnosis of rheumatoid arthritis. A diagnosis of parvovirus B19 infection should be considered during the initial visit of patients with polyarthralgia/polyarthritis.
authors.affiliation: Department of Internal Medicine, University of Iowa College of Medicine, Iowa City.
authors.forename: S J
authors.initials: SJ
authors.lastname: Naides
authors.forename: L L
authors.initials: LL
authors.lastname: Scharosch
authors.forename: F
authors.initials: F
authors.lastname: Foto
authors.forename: E J
authors.initials: EJ
authors.lastname: Howard
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D004890:Erythema / Q000382:microbiology; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007592:Joint Diseases / Q000382:microbiology*; D010322:Parvoviridae Infections / Q000175:diagnosis
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M