The future anatomic pathology laboratory for molecular diagnosis and prognosis: circa 1990-95.
Molecular biology provides analytical tools for the study of human disease. These clinical assays can help make a diagnosis, predict a prognosis, or elucidate the pathogenesis of poorly understood diseases. The detection and/or quantitation of specific genes, messenger RNA's, and their protein products provide diagnostic and prognostic information for physicians. Illustrative applications of some of these techniques in human virus infection and breast cancer will suggest the future direction that an anatomic pathology laboratory should consider if it is to provide optimal and competitive service to physicians.
Robb
J A
JA
Department of Pathology, Green Hospital of Scripps Clinic, La Jolla, CA 92037.
D000911:Antibodies, Monoclonal; D001943:Breast Neoplasms / Q000235:genetics; D005260:Female; D005821:Genetic Techniques / Q000639:trends*; D006561:Herpes Simplex / Q000175:diagnosis; D006801:Humans; D007150:Immunohistochemistry; D009693:Nucleic Acid Hybridization; D027383:Papillomaviridae; D010338:Pathology, Clinical / Q000639:trends*; D010455:Peptides / Q000138:chemical synthesis; D011379:Prognosis; D014412:Tumor Virus Infections / Q000175:diagnosis; D014591:Uterine Diseases / Q000175:diagnosis
D000911:Antibodies, Monoclonal; D010455:Peptides