title: [The treatment of scleroderma with the enzyme preparation collalysine].
abstract: Examinations of 42 patients with local scleroderma have revealed increased hydroxyproline and glycosaminoglycane excretion and impaired cellular and humoral immunity, these shifts correlating with the type and severity of the disease. Collalysin therapy resulted in a good clinical effect and improvement of the immune and metabolic parameters.
authors.forename: S I
authors.initials: SI
authors.lastname: Dovzhanskiĭ
authors.forename: A I
authors.initials: AI
authors.lastname: Zav'ialov
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D008297:Male; D003012:Microbial Collagenase / Q000627:therapeutic use*; D008875:Middle Aged; D012074:Remission Induction; D012594:Scleroderma, Localized / Q000188:drug therapy* / Q000276:immunology / Q000652:urine
chemical_list: D003012:Microbial Collagenase
vernacular_title: Lechenie sklerodermii fermentnym preparatom kollalizinom.