title: [Macrocytosis, polyneuropathy and posterior column disorders caused by malabsorption of protein-bound vitamin B12].
abstract: This case report concerns a patient with a vitamin B12 deficiency and a normal Schilling test, who had macrocytosis of many years' duration and finally polyneuropathy. All known causes of a vitamin B12 deficiency were excluded. When the Schilling test was performed with egg consumption, excretion of vitamin B12 was clearly diminished. It appears highly likely that this vitamin B12 deficiency developed as a result of malabsorption of protein-bound vitamin B12.
authors.affiliation: Afd. Interne Geneeskunde, Bronovo Ziekenhuis, Gravenhage.
authors.forename: A
authors.initials: A
authors.lastname: Mazure
authors.forename: R
authors.initials: R
authors.lastname: Bieger
authors.forename: P C
authors.initials: PC
authors.lastname: Lambregts
authors.forename: K S
authors.initials: KS
authors.lastname: Wiarda
mesh_terms: D000328:Adult; D000748:Anemia, Macrocytic / Q000209:etiology*; D004044:Dietary Proteins / Q000378:metabolism; D005260:Female; D006801:Humans; D008286:Malabsorption Syndromes / Q000150:complications*; D010523:Peripheral Nervous System Diseases / Q000209:etiology*; D014805:Vitamin B 12 / Q000378:metabolism*; D014806:Vitamin B 12 Deficiency / Q000150:complications* / Q000378:metabolism
chemical_list: D004044:Dietary Proteins; D014805:Vitamin B 12
vernacular_title: Macrocytose, polyneuropathie en achterstrengstoornissen door malabsorptie van eiwitgebonden vitamine B12.