title: Epizootiologic association between feline immunodeficiency virus infection and feline leukemia virus seropositivity.
abstract: Five hundred twenty-one feline serum samples submitted to the Texas Veterinary Medical Diagnostic Laboratory between Nov 1, 1988, and Jan 31, 1989 were tested for antibody to feline immunodeficiency virus (FIV) by use of an ELISA. The prevalence of FIV infection in this population was 11.3% (95% confidence interval: 8.6 to 14.0%). Serologic test results for FeLV were available for 156 of the 521 cats. A significant (P = 0.008) association between FIV infection and FeLV seropositivity was observed; FeLV-positive cats were nearly 4 times more likely to be seropositive for FIV than were FeLV-negative cats. The association remained statistically significant (P = 0.021) after adjusting for age and gender, using multiple-logistic regression analysis.
authors.affiliation: Department of Large Animal Medicine and Surgery, Texas Veterinary Medical Center, Texas A&M University, College Station 77843.
authors.forename: N D
authors.initials: ND
authors.lastname: Cohen
authors.forename: C N
authors.initials: CN
authors.lastname: Carter
authors.forename: M A
authors.initials: MA
authors.lastname: Thomas
authors.forename: T L
authors.initials: TL
authors.lastname: Lester
authors.forename: A K
authors.initials: AK
authors.lastname: Eugster
mesh_terms: D000367:Age Factors; D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D002371:Cat Diseases / Q000453:epidemiology*; D002415:Cats; D005260:Female; D007153:Immunologic Deficiency Syndromes / Q000150:complications / Q000453:epidemiology / Q000662:veterinary*; D007938:Leukemia / Q000150:complications / Q000453:epidemiology / Q000662:veterinary*; D005256:Leukemia Virus, Feline / Q000276:immunology; D008297:Male; D015995:Prevalence; D012044:Regression Analysis; D012190:Retroviridae / Q000276:immunology; D012192:Retroviridae Infections / Q000150:complications / Q000453:epidemiology / Q000662:veterinary*; D012737:Sex Factors; D013781:Texas / Q000453:epidemiology
chemical_list: D000914:Antibodies, Viral