Are booster doses of poliovirus vaccine necessary?
In this issue of VACCINE, Böttiger points out that 'When the booster dose of polio vaccine at the age of 6 years was introduced (in Sweden) in the 1960s ... neither the necessity, nor the appropriate age for a booster had been scientifically evaluated'. If such a scientific evaluation were to be made now, what insights might emerge that would influence our thinking about booster doses and the associated implications for effective vaccination programmes and policy?
Salk
J
J
International Health Sciences, Salk Institute, San Diego, California 92138-9216.
D000367:Age Factors; D000914:Antibodies, Viral / Q000276:immunology*; D002648:Child; D000075202:Contraindications; D006801:Humans; D007117:Immunization, Secondary; D007156:Immunologic Memory; D007223:Infant; D017955:Poliovirus / Q000276:immunology*; D011054:Poliovirus Vaccine, Inactivated / Q000627:therapeutic use*; D015397:Program Evaluation; D013997:Time Factors
D000914:Antibodies, Viral; D011054:Poliovirus Vaccine, Inactivated