title: Interaction of lipocortin I with peripheral-type benzodiazepine binding sites.
abstract: Recombinant rat lipocortin I increased [3H]PK 11195 binding to porcine aortic smooth muscle membranes, whereas a polyclonal anti-rat lipocortin I antiserum decreased both basal and lipocortin I-enhanced [3H]PK 11195 binding. The results suggest the possibility of lipocortin I being involved in the function of peripheral-type benzodiazepine binding sites.
authors.affiliation: Shionogi Research Laboratories, Shionogi & Co. Ltd., Osaka, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Mihara
authors.forename: T
authors.initials: T
authors.lastname: Sakata
authors.forename: M
authors.initials: M
authors.lastname: Fujimoto
mesh_terms: D000818:Animals; D017302:Annexins; D002135:Calcium-Binding Proteins / Q000276:immunology / Q000494:pharmacology*; D007074:Immunoglobulin G / Q000276:immunology / Q000378:metabolism; D066298:In Vitro Techniques; D007546:Isoquinolines / Q000494:pharmacology; D007700:Kinetics; D009131:Muscle, Smooth, Vascular / Q000166:cytology / Q000378:metabolism; D010740:Phospholipases / Q000037:antagonists & inhibitors*; D051381:Rats; D011963:Receptors, GABA-A / Q000187:drug effects*; D011994:Recombinant Proteins / Q000378:metabolism; D013552:Swine
chemical_list: D017302:Annexins; D002135:Calcium-Binding Proteins; D007074:Immunoglobulin G; D007546:Isoquinolines; D011963:Receptors, GABA-A; D011994:Recombinant Proteins; D010740:Phospholipases; C037850:PK 11195