Ethanol and neuronal calcium channels.
Ethanol alters voltage-dependent calcium channels and receptor-operated channels which transport calcium [e.g., the ion channels associated with N-methyl-D-aspartate (NMDA) receptors]. However, the question which still remain unanswered is whether these modifications have any physiological significance. This review will focus on the effects of ethanol on various calcium-related parameters with an emphasis on the possible relevance to the behavioral effects elicited by ethanol.
Leslie
S W
SW
Division of Pharmacology, College of Pharmacy, University of Texas at Austin 78712.
Brown
L M
LM
Dildy
J E
JE
Sims
J S
JS
D000818:Animals; D015220:Calcium Channels / Q000187:drug effects / Q000378:metabolism*; D000431:Ethanol / Q000494:pharmacology*; D006801:Humans; D009474:Neurons / Q000187:drug effects / Q000378:metabolism*
D015220:Calcium Channels; D000431:Ethanol