[Hepatocellular carcinoma with a complete remission of bone metastasis achieved by arterial chemotherapy].
Reported is the case of a hepatocellular carcinoma with a complete remission of the bone metastasis by arterial chemotherapy. The patient was 60 year old male, with the chief complaint being a tumor at the right side of the chest. The diagnosis was a hepatocellular carcinoma with a bone metastasis at the right 10th rib. The bone tumor showed no decrease in size after an intra-arterial injection of adriamycin, and radiation and or hyperthermia. Therefore, intra-arterial injections of mitomycin C mixed with lipiodol were instituted through the intercostal artery, and no bone tumor was noted after start of this therapy. Although the patient subsequently died, microscopic examination of a specimen obtained at autopsy revealed no malignant cells at the right 10th rib. Intra-arterial injections of anticancer agents mixed with lipiodol therefore are thought to be useful for the treatment of a bone metastasis.
Fukushima
H
H
2nd Dept. of Med., Kurume Univ. School of Med.
Hirai
K
K
Shimada
M
M
Aoki
Y
Y
Iwai
I
I
Yamashita
K
K
Fujimoto
T
T
Tanaka
M
M
Majima
Y
Y
Nakashima
O
O
D001859:Bone Neoplasms / Q000188:drug therapy* / Q000556:secondary; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy* / Q000556:secondary; D006801:Humans; D007269:Injections, Intra-Arterial; D007459:Iodized Oil / Q000008:administration & dosage / Q000627:therapeutic use; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage* / Q000627:therapeutic use; D012074:Remission Induction; D012272:Ribs
D008937:Mitomycins; D016685:Mitomycin; D007459:Iodized Oil