[Clinical efficacy of ifosfamide for liver metastasis of breast cancer].
Chemotherapy for liver metastasis of breast cancer has rarely been found effective. We devised a new regimen of chemotherapy for recurrent breast cancer mainly using ifosfamide. It was found clinically applicable and particularly effective for liver metastasis. The tumor decreased in size and the levels of various tumor-markers markedly decreased following drug administration. This treatment has made for longer survival for some patients. Side effects could be well controlled with steroid hormones and Na-bicarbonate.
Funahashi
H
H
Dept. of Surgery II, Nagoya University School of Medicine.
Sato
Y
Y
Imai
T
T
Kato
N
N
Ando
K
K
Oike
E
E
Odaka
K
K
Ono
M
M
Narita
T
T
Kato
M
M
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001639:Bicarbonates / Q000008:administration & dosage; D001943:Breast Neoplasms / Q000473:pathology*; D004317:Doxorubicin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage / Q000627:therapeutic use*; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary; D008525:Medroxyprogesterone / Q000008:administration & dosage / Q000031:analogs & derivatives; D017258:Medroxyprogesterone Acetate; D016685:Mitomycin; D008937:Mitomycins / Q000008:administration & dosage; D012964:Sodium / Q000008:administration & dosage; D017693:Sodium Bicarbonate
D001639:Bicarbonates; D008937:Mitomycins; D016685:Mitomycin; D004317:Doxorubicin; D017693:Sodium Bicarbonate; D012964:Sodium; D017258:Medroxyprogesterone Acetate; D008525:Medroxyprogesterone; D005472:Fluorouracil; D007069:Ifosfamide