Analysis of menstrual records of women immunized with anti-hCG vaccines inducing antibodies partially cross-reactive with hLH.
Menstrual data of 13 control subjects and 88 subjects immunized with three beta-hCG-based vaccine formulations were analysed. Immunization did not change the menstrual regularity; bleeding days were normal (3-7 days) and 89% of the menstrual cycles were within the normal range of 22-35 days. Irregular (short or long) cycles were observed in both immunized and control groups. These were, however, unrelated to prevailing anti-hCG antibody titres or to cross-reactivity of antibodies with hLH.
Kharat
I
I
National Institute of Immunology, New Delhi.
Nair
N S
NS
Dhall
K
K
Sawhney
H
H
Krishna
U
U
Shahani
S M
SM
Banerjee
A
A
Roy
S
S
Kumar
S
S
Hingorani
V
V
D006063:Chorionic Gonadotropin / Q000276:immunology*; D002986:Clinical Trials as Topic; D003267:Contraception; D003269:Contraception, Immunologic; D003429:Cross Reactions; D005260:Female; D006801:Humans; D007986:Luteinizing Hormone / Q000276:immunology; D008597:Menstrual Cycle; D008598:Menstruation; D014612:Vaccines / Q000494:pharmacology
D006063:Chorionic Gonadotropin; D014612:Vaccines; D007986:Luteinizing Hormone