Cholangiocarcinoma in an immunosuppressed kidney transplant patient. A case report and review of literature.
Immunosuppressed transplant recipients are susceptible to an increased incidence of certain malignancies. There is a significant relationship between tumour incidence and HLA-A and HLA-B mismatch. We present a patient who developed a cholangiocarcinoma ten years after a cadaveric donor renal transplant. Carcinoma of the main hepatic duct junction is a rare and difficult condition to treat. Surgical resection offers the best prolonged survival, but is rarely possible. Most of these patients will therefore require palliative biliary decompression.
Storms
P
P
Department of Surgery, Royal Devon and Exeter Hospital, U.K., Great Britain.
Ramli
Y
Y
D002759:Adenoma, Bile Duct / Q000150:complications* / Q000276:immunology; D000368:Aged; D001650:Bile Duct Neoplasms / Q000150:complications* / Q000276:immunology; D005260:Female; D015234:HLA-A Antigens / Q000276:immunology; D015235:HLA-B Antigens / Q000276:immunology; D006500:Hepatic Duct, Common; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D016030:Kidney Transplantation
D015234:HLA-A Antigens; D015235:HLA-B Antigens; D007166:Immunosuppressive Agents