title: [Detection of human papillomavirus (HVP) 16/18 infections of the vaginal uterine cervix in females before and following conisation].
abstract: 280 women have been tested by FISH to detect an HPV 16/18-infection of the portio uteri. In a group of 133 women treated by conisation (all with a history of abnormal smear and colposcopy) 67 (50%) were positive for HPV 16/18 DNA before the operation. Follow up examinations of 20 cases with positive HPV 16/18 test before conisation, showed 6 and 12 months after operation only in 3 cases a persistence of HPV 16/18 infection. Only 5 (6.4%) of 78 women with a history of conisation and diagnosis CIN III some years ago were positive for HPV 16/18. In another group of 47 elderly women, treated by abrasio and with normal cervical histology, only 5 (10.6%) had a positive result in the HPV 16/18 FISH-test. 2 (10.6%) of 22 women with normal smear and colposcopy (control group) were positive for HPV 16/18.
authors.affiliation: Klinik für Gynäkologie und Geburtshilfe, Bereichs Medizin (Charité) der Humboldt-Universität zu Berlin.
authors.forename: W
authors.initials: W
authors.lastname: Götze
authors.forename: J
authors.initials: J
authors.lastname: Jantschak
authors.forename: A
authors.initials: A
authors.lastname: Kohls
authors.forename: D
authors.initials: D
authors.lastname: Elling
authors.forename: I
authors.initials: I
authors.lastname: Schildhaus
mesh_terms: D000328:Adult; D000368:Aged; D002584:Cervix Uteri / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D015344:DNA Probes, HPV; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D027383:Papillomaviridae / Q000302:isolation & purification*; D014412:Tumor Virus Infections / Q000382:microbiology / Q000473:pathology / Q000601:surgery*; D002583:Uterine Cervical Neoplasms / Q000382:microbiology / Q000473:pathology / Q000601:surgery*
chemical_list: D015344:DNA Probes, HPV
vernacular_title: Nachweis von humanen Papillom Virus (HPV) 16/18-Infektionen der Portio vaginalis cervicis uteri bei Frauen vor und nach Konisation.