title: High-renin malignant hypertension secondary to an aldosterone-producing adenoma.
abstract: Malignant hypertension and high plasma renin activity was found in a 39-year-old woman with an aldosterone-producing adenoma. Only 3 similar cases have been previously reported, and all patients died before or after identification of the adenoma. The present paper documents the first reported case of a successfully managed high-renin malignant hypertension secondary to an aldosterone-producing adenoma. Regardless of its sporadic occurrence and common presence with low plasma renin activity, primary aldosteronism should be considered as a possible underlying cause of high-renin malignant hypertension.
authors.affiliation: Department of Internal Medicine, Fukuoka University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Ideishi
authors.forename: K
authors.initials: K
authors.lastname: Kishikawa
authors.forename: A
authors.initials: A
authors.lastname: Kinoshita
authors.forename: M
authors.initials: M
authors.lastname: Sasaguri
authors.forename: M
authors.initials: M
authors.lastname: Ikeda
authors.forename: S
authors.initials: S
authors.lastname: Takebayashi
authors.forename: K
authors.initials: K
authors.lastname: Arakawa
mesh_terms: D000236:Adenoma / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D000306:Adrenal Cortex Neoplasms / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D000328:Adult; D000450:Aldosterone / Q000096:biosynthesis*; D005260:Female; D006801:Humans; D006974:Hypertension, Malignant / Q000097:blood / Q000209:etiology* / Q000473:pathology; D012083:Renin / Q000097:blood*
chemical_list: D000450:Aldosterone; D012083:Renin