title: [The neurotropic effects of hydrocortisone in surviving slices of the rat olfactory cortex].
abstract: The effects of hydrocortisone on short-term habituation, post-tetanic potentiation, fluctuations of the amplitude of focal potentials (FPs) and slow after-hyperpolarization were studied in the olfactory cortex slice preparations. Hydrocortisone (10(-5)-10(-4) M) inhibited the habituation but facilitated and prolonged the post-tetanic potentiation of the FPs. The hormone increased the fluctuations of the FPs and exerted no effect on slow after-hyperpolarization evoked by a brief orthodromic stimulation. The neurotrophic effects of the hydrocortisone seem to reflect adaptive reactions of nervous system under stress conditions.
authors.forename: A A
authors.initials: AA
authors.lastname: Mokrushin
authors.forename: T R
authors.initials: TR
authors.lastname: Bagaeva
authors.forename: I A
authors.initials: IA
authors.lastname: Gerasimova
authors.forename: N A
authors.initials: NA
authors.lastname: Emel'ianov
mesh_terms: D000818:Animals; D002540:Cerebral Cortex / Q000187:drug effects / Q000502:physiology; D046508:Culture Techniques; D006185:Habituation, Psychophysiologic / Q000187:drug effects / Q000502:physiology; D006854:Hydrocortisone / Q000494:pharmacology*; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D008568:Memory / Q000187:drug effects / Q000502:physiology; D009474:Neurons / Q000187:drug effects / Q000502:physiology; D009830:Olfactory Bulb / Q000187:drug effects* / Q000502:physiology; D051381:Rats
chemical_list: D006854:Hydrocortisone
vernacular_title: Neĭrotropnye éffekty gidrokortizona v perezhivaiushchikh srezakh oboniatel'noĭ kory mozga krys.