Cultivation of foot-and-mouth disease virus in BHK21 cells grown in microcarrier culture system.
When BHK21 cells were grown according to the microcarrier's system, they reached the highest concentration in 72 hrs. The infectivity of Foot-and-Mouth Disease (FMD) virus in BHK21 microcarrier culture increased 10 times compared with the conventional monolayer culture in rolling bottles.
Ferrari
M
M
Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia, Brescia, Italy.
Losio
M N
MN
Gualandi
G L
GL
Bugnetti
M
M
D000818:Animals; D005537:Aphthovirus / Q000254:growth & development*; D002460:Cell Line; D007700:Kinetics; D014776:Virus Cultivation