[Primary cutaneous Ki-1-lymphoma].
With the help of immunohistochemical techniques and new antibodies developed in the last few years, we were able to identify 2 cases of nodular tumors of the skin as highly malignant Ki-1 lymphomas. The clinical course was characterized by the development of multiple skin tumors without any evidence of systemic involvement. After the excision of several skin tumors; we performed chemotherapy with the MACOP-B regimen. In one of our patients, however, this treatment could not prevent the occurrence of further tumors. Possibly, the cutaneous anaplastic Ki-1 lymphomas presented here are closely related to or even identical with mycosis fungoides d'emblée.
Berger
H
H
Abteilung Dermato-Histologie, Universitäts-Hautklinik Göttingen.
Bergholz
M
M
Heil
M
M
D000368:Aged; D000943:Antigens, Differentiation / Q000032:analysis*; D000951:Antigens, Neoplasm / Q000032:analysis*; D001706:Biopsy; D005153:Facial Neoplasms / Q000473:pathology; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology; D006801:Humans; D007124:Immunoenzyme Techniques; D017730:Ki-1 Antigen; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*; D013601:T-Lymphocytes / Q000473:pathology*
D000943:Antigens, Differentiation; D000951:Antigens, Neoplasm; D017730:Ki-1 Antigen
Das primäre kutane Ki-1-Lymphom.