title: Comparative study of hydroxyapatite and titanium dental implants in dogs.
abstract: This study compares the clinical performances and histologic response in dogs to a cylindrical implant with a surface consisting of dense hydroxyapatite (HA) and a threaded titanium implant in functionally loaded and unloaded conditions. Implantation was performed in five dogs, which were killed at 2 or 4 months postfunctional condition (4 or 6 months after implantation). Clinical evaluation showed that neither implant demonstrated significant movement, and assessment of gingival inflammation and sulcus depth showed no significant differences between them. After axial sectioning, the titanium implants were easily removed from the bone, whereas the HA-coated implants were adherent to the bone. Histologically, both implants showed osteogenic ingrowth to the surface in functional and nonfunctional conditions. High-magnification scanning electron micrographs of plastic sections showed that a portion of the interface between the HA-coated implant and the bone showed no gap, whereas gaps were observed at all interfaces with the titanium implant. Histomorphometric analysis by light microscopy indicated that there was no significant difference in the percent bone contact length. Clinically, the two implants behaved similarly.
authors.affiliation: Department of Removable Prosthetic Dentistry, School of Dentistry, Hokkaido University, Sapporo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kohri
authors.forename: E P
authors.initials: EP
authors.lastname: Cooper
authors.forename: J L
authors.initials: JL
authors.lastname: Ferracane
authors.forename: D F
authors.initials: DF
authors.lastname: Waite
mesh_terms: D000539:Alveolar Process / Q000473:pathology / Q000648:ultrastructure; D000818:Animals; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D004285:Dogs; D017886:Durapatite; D006882:Hydroxyapatites; D008409:Mastication; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D016348:Osseointegration; D013499:Surface Properties; D014025:Titanium
chemical_list: D015921:Dental Implants; D006882:Hydroxyapatites; D017886:Durapatite; D014025:Titanium