title: [Lactic acidosis--recognition and treatment of an important complication of perioperative parenteral nutrition].
abstract: We report 5 cases of acute vitamin B-1 induced lactic acidosis in surgical patients receiving parenteral nutrition. In all patients treatment with vitamin B-1 induced a dramatical improvement of clinical findings. 4 patients recovered completely, 1 patient died from already developed irreversible cardiocirculatory failure. These cases underline the need for regular vitamin B-1 substitution in patients with parenteral nutrition and preoperatively in alcoholics and in patients, in whom a sufficient food intake can not be assured.
authors.affiliation: Chirurgische Universitätsklinik Heidelberg.
authors.forename: C
authors.initials: C
authors.lastname: Wilmanns
authors.forename: H
authors.initials: H
authors.lastname: Witzigmann
authors.forename: P
authors.initials: P
authors.lastname: Schlag
authors.forename: J
authors.initials: J
authors.lastname: Witte
authors.forename: C
authors.initials: C
authors.lastname: Herfarth
mesh_terms: D000140:Acidosis, Lactic / Q000175:diagnosis* / Q000188:drug therapy; D002288:Adenocarcinoma, Mucinous / Q000601:surgery; D000328:Adult; D000368:Aged; D003424:Crohn Disease / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D010195:Pancreatitis / Q000601:surgery; D011183:Postoperative Complications / Q000175:diagnosis* / Q000188:drug therapy; D013274:Stomach Neoplasms / Q000601:surgery; D013831:Thiamine / Q000008:administration & dosage; D013832:Thiamine Deficiency / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D013831:Thiamine
vernacular_title: Lactatacidose--Erkennung und Behandlung einer wichtigen Komplikation unter perioperativer parenteraler Ernährung.