title: [Changes in serum hormones and the spermiogram in patients with malignant testicular tumors following radiation and cytostatic drug therapy].
abstract: In 53 patients suffering from testicular cancer it was reviewed whether the changes of spermatogenesis due to radiation or chemotherapy are reflected by the sexual hormones (FSH, LH, T). After both therapeutic measures a reduction of the number of spermatic cells and volume of sperm was demonstrated. The reduction of spermatic cells was followed by a simultaneous increase of FSH and LH levels, whereas the testosterone level did remain normal.
authors.affiliation: Klinik für Nephrologie und Urologie, Bezirkskrankenhauses Ernst Scheffler, Aue.
authors.forename: V
authors.initials: V
authors.lastname: Barth
authors.forename: R
authors.initials: R
authors.lastname: Hums
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D004407:Dysgerminoma / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D005640:Follicle Stimulating Hormone / Q000097:blood; D012739:Gonadal Steroid Hormones / Q000097:blood*; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D011832:Radiation Injuries / Q000209:etiology*; D013076:Sperm Count / Q000187:drug effects* / Q000528:radiation effects*; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D013739:Testosterone / Q000097:blood
chemical_list: D012739:Gonadal Steroid Hormones; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone
vernacular_title: Serumhormone und Spermiogrammveränderungen bei Patienten mit malignen Hodentumoren nach Strahlen- und Zytostatikatherapie.