Lack of evidence for seroconversion to human immunodeficiency virus in recipients of anti-D immunoglobulin containing HIV antibody.
Twenty nine Rh negative women who had received injections of anti-D (Rho) immunoglobulin preparations (from an Indian firm) contaminated with antibody to human immunodeficiency virus (HIV), were tested for seroconversion to HIV, 14-38 wk after injections. All 29 were negative for HIV antibody, indicating that infectious HIV or immunogenic concentrations of inactivated HIV were not present in the investigated immunoglobulin product.
Babu
P G
PG
Department of Virology & Immunology, Christian Medical College Hospital, Vellore.
Cherian
T
T
Jairaj
P K
PK
Jayakumari
H
H
John
T J
TJ
D004340:Drug Contamination; D005260:Female; D006678:HIV / Q000276:immunology*; D015483:HIV Antibodies / Q000032:analysis*; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D018029:Rho(D) Immune Globulin
D015483:HIV Antibodies; D007136:Immunoglobulins; D018029:Rho(D) Immune Globulin