Identification of a mitochondrial receptor complex required for recognition and membrane insertion of precursor proteins.
The mitochondrial import receptors MOM19 and MOM72 form a complex with two other proteins of the mitochondrial outer membrane, MOM38 and MOM22. This receptor complex is involved in recognition, membrane insertion and translocation of precursor proteins with MOM38 constituting (at least part of) the general insertion site GIP.
Kiebler
M
M
Institut für Physiologische Chemie, Universität München, Germany.
Pfaller
R
R
Söllner
T
T
Griffiths
G
G
Horstmann
H
H
Pfanner
N
N
Neupert
W
W
D000595:Amino Acid Sequence; D000906:Antibodies; D001483:Base Sequence; D001692:Biological Transport; D005656:Fungal Proteins; D007425:Intracellular Membranes / Q000378:metabolism / Q000648:ultrastructure; D007700:Kinetics; D008565:Membrane Proteins / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D026901:Membrane Transport Proteins; D016253:Microscopy, Immunoelectron; D008928:Mitochondria / Q000378:metabolism*; D000226:Mitochondrial ADP, ATP Translocases / Q000378:metabolism; D008969:Molecular Sequence Data; D009492:Neurospora crassa / Q000235:genetics / Q000378:metabolism*; D011498:Protein Precursors / Q000235:genetics* / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000302:isolation & purification / Q000378:metabolism*; D018160:Receptors, Cytoplasmic and Nuclear; D011983:Receptors, Purinergic / Q000302:isolation & purification / Q000378:metabolism*; D013367:Submitochondrial Particles / Q000378:metabolism / Q000648:ultrastructure
C037688:ADP-ATP carrier receptor; D000906:Antibodies; D005656:Fungal Proteins; C066557:MOM19 protein, Neurospora crassa; C066556:MOM38 protein, Neurospora crassa; D008565:Membrane Proteins; D026901:Membrane Transport Proteins; D011498:Protein Precursors; D011956:Receptors, Cell Surface; D018160:Receptors, Cytoplasmic and Nuclear; D011983:Receptors, Purinergic; D000226:Mitochondrial ADP, ATP Translocases