title: Prospective evaluation of the role of fine-needle aspiration biopsy in the diagnosis and management of patients with palpable solid breast lesions.
abstract: To evaluate the role of fine-needle aspiration biopsy (FNAB) in the diagnosis and management of patients with palpable, solid and suspicious breast lesions, a total of 107 FNABs were performed on 98 patients under the prospective FNAB protocol. Eight-four FNABs were positive for breast carcinomas; of these 84 positive FNABs, 80 underwent mastectomy without open biopsy or frozen section. Our data showed a sensitivity of 95 per cent and a specificity of 100 per cent for diagnosis of breast malignancies on these patients. We concluded that FNAB is a simple, reliable, and cost-effective diagnostic procedure for patients with palpable breast carcinomas.
authors.affiliation: Department of Surgery, De Paul Hospital, Norfolk, Virginia 23505.
authors.forename: H A
authors.initials: HA
authors.lastname: Gelabert
authors.forename: J G
authors.initials: JG
authors.lastname: Hsiu
authors.forename: J T
authors.initials: JT
authors.lastname: Mullen
authors.forename: A H
authors.initials: AH
authors.lastname: Jaffe
authors.forename: N A
authors.initials: NA
authors.lastname: D'Amato
mesh_terms: D000465:Algorithms; D001707:Biopsy, Needle; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000191:economics / Q000473:pathology*; D002277:Carcinoma / Q000191:economics / Q000473:pathology; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000191:economics / Q000473:pathology*; D003362:Cost-Benefit Analysis; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D010173:Palpation; D011237:Predictive Value of Tests; D011446:Prospective Studies