title: Interaction between X-ray- and restriction endonuclease-induced lesions in the formation of chromosomal aberrations.
abstract: Experiments were performed to analyze the possible interaction between lesions induced by X-rays and restriction endonucleases in the production of chromosome-type exchanges. A stronger interaction was found between X-rays and the AluI-induced 'blunt termini' lesions than between X-rays and the BamHI-induced 'cohesive termini' lesions.
authors.affiliation: Centro di Genetica Evoluzionistica del CNR, c/o Dipartimento Darwin, Università La Sapienza, Rome, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Tanzarella
authors.forename: R
authors.initials: R
authors.lastname: De Salvia
authors.forename: F
authors.initials: F
authors.lastname: Degrassi
authors.forename: M
authors.initials: M
authors.lastname: Fiore
authors.forename: F
authors.initials: F
authors.lastname: Palitti
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000187:drug effects / Q000528:radiation effects*; D006224:Cricetinae; D004262:DNA Restriction Enzymes / Q000633:toxicity*; D015245:Deoxyribonuclease BamHI; D015252:Deoxyribonucleases, Type II Site-Specific; D009153:Mutagens
chemical_list: D009153:Mutagens; D004262:DNA Restriction Enzymes; D015245:Deoxyribonuclease BamHI; C024669:endodeoxyribonuclease AluI; D015252:Deoxyribonucleases, Type II Site-Specific