Transduction of receptor signal into modulation of effector activity by G proteins: the first 20 years or so ....
G proteins are central to the transduction of many receptor signals. I review the "firsts" that have led to our current knowledge and delineate some of the issues being investigated in several laboratories worldwide.--Birnbaumer, L. Transudction of receptor signal into modulation of effector activity by G proteins: the first 20 years or so...FASEB J. 4:3068-3078; 1990.
Birnbaumer
L
L
Department of Cell Biology, Baylor College of Medicine, Houston, Texas 77030.
D000262:Adenylyl Cyclases / Q000378:metabolism; D000818:Animals; D019204:GTP-Binding Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D006160:Guanosine Triphosphate / Q000502:physiology; D046911:Macromolecular Substances; D011956:Receptors, Cell Surface / Q000502:physiology*; D015398:Signal Transduction
D046911:Macromolecular Substances; D011956:Receptors, Cell Surface; D006160:Guanosine Triphosphate; D019204:GTP-Binding Proteins; D000262:Adenylyl Cyclases