[The modulation of postural asymmetry in recipient animals under the influence of the cerebrospinal fluid from patients with manic-depressive psychosis].
Suboccipital administration of cerebrospinal fluid of patients with affective disorders elicits a pose asymmetry in rats-recipients; the character of the pose asymmetry depends on the phase of donor's disease: cerebrospinal fluid of manic patients elicits a relative flexion of the right posterior limb, of depressive patients--a relative flexion of the left posterior limb. High-molecular and low-molecular fractions of the cerebrospinal fluid were active, trypsin treatment led to disappearance of the effect. The results suggest a significant role of protein components of the cerebrospinal fluid in the organization of the symptom of functional asymmetry of the central nervous system under affective disorders.
Tokarev
A V
AV
Zhdanov
I V
IV
D000818:Animals; D001714:Bipolar Disorder / Q000134:cerebrospinal fluid*; D002555:Cerebrospinal Fluid / Q000737:chemistry / Q000502:physiology*; D003392:Cranial Sinuses; D004292:Dominance, Cerebral / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D007267:Injections / Q000379:methods; D011187:Posture / Q000502:physiology*; D051381:Rats
Moduliatsiia poznoĭ asimmetrii u zhivotnykh-retsipientov pod vliianiem tserebrospinal'noĭ zhidkosti bol'nykh maniakal'no-depressivnym psikhozom.