title: Transcatheter hepatic segmental arterial embolization using lipiodol mixed with an anticancer drug and Gelfoam particles for hepatocellular carcinoma.
abstract: Transcatheter hepatic segmental arterial chemoembolization using Lipiodol mixed with an anticancer drug followed by the injection of Gelfoam particles, introduced into the tumor-bearing hepatic segment as the target area (segmental Lipiodol-TAE), was carried out in 54 patients with hepatocellular carcinoma (HCC), 7 of whom were later resected. In 5 of the resected 7 cases, complete necrosis was histologically verified. No death due to HCC was encountered in 47 nonoperated cases, and better therapeutic results were obtained with segmental Lipiodol-TAE. It was concluded that this technique does not adversely affect normal tissues, and it does reinforce the effect of TAE.
authors.affiliation: Department of Radiology, Nara Medical University, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Uchida
authors.forename: H
authors.initials: H
authors.lastname: Ohishi
authors.forename: N
authors.initials: N
authors.lastname: Matsuo
authors.forename: K
authors.initials: K
authors.lastname: Nishimine
authors.forename: S
authors.initials: S
authors.lastname: Ohue
authors.forename: Y
authors.initials: Y
authors.lastname: Nishimura
authors.forename: M
authors.initials: M
authors.lastname: Maeda
authors.forename: T
authors.initials: T
authors.lastname: Yoshioka
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D004317:Doxorubicin / Q000008:administration & dosage* / Q000627:therapeutic use; D004621:Embolization, Therapeutic; D005781:Gelatin Sponge, Absorbable; D006499:Hepatic Artery; D006801:Humans; D007459:Iodized Oil / Q000008:administration & dosage*; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D008875:Middle Aged
chemical_list: D007459:Iodized Oil; D004317:Doxorubicin