[Granulocytic sarcoma (chloroma): rare extramedullary tumors associated with acute non-lymphoblastic leukemia].
The authors report 5 new cases of pediatric granulocytic sarcomas. These rare extramedullary tumors are composed of immature granulocytic cells, usually associated with an acute non lymphoblastic leukemia, but may appear several months before. Their characteristics are exposed (epidemiology, clinical features, cytology and cytogenetics), and therapeutic rules are discussed, especially for the granulocytic sarcomas without evidence of bone marrow involvement. The prognosis is known to be poor.
Capdeville
R
R
Unité d'hématologie pédiatrique, Hôpital Debrousse, Lyon, France.
Bertrand
Y
Y
Manel
A M
AM
Charrin
C
C
Souillet
G
G
Philippe
N
N
D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007951:Leukemia, Myeloid / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008297:Male; D011379:Prognosis
Sarcomes granulocytaires (chloromes): tumeurs extramédullaires rares associées aux leucémies aiguës non lymphoblastiques.