Crystallization of human interleukin-8. A protein chemotactic for neutrophils and T-lymphocytes.
Interleukin-8 is a 72-residue peptide which is chemotactic for neutrophils and T-lymphocytes. It crystallizes in space group P3(1)21 or P3(2)21 with unit cell dimensions of a = b = 40.3 and c = 90.1 A. X-ray diffraction data have been measured to 1.6-A resolution.
Baldwin
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National Cancer Institute, Frederick Cancer Research Facility, Biological Response Modifiers Program-National Cancer Institute, Frederick, Maryland 21701.
Franklin
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Appella
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Yamada
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Matsushima
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Wlodawer
A
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Weber
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D000595:Amino Acid Sequence; D000818:Animals; D002417:Cattle; D002630:Chemotactic Factors / Q000235:genetics / Q000302:isolation & purification* / Q000502:physiology; D002634:Chemotaxis, Leukocyte; D003460:Crystallization; D004247:DNA / Q000235:genetics; D015723:Gene Library; D005796:Genes; D006801:Humans; D016209:Interleukin-8; D007378:Interleukins / Q000235:genetics / Q000302:isolation & purification* / Q000502:physiology; D008969:Molecular Sequence Data; D009504:Neutrophils / Q000502:physiology*; D010978:Platelet Factor 4; D011487:Protein Conformation; D012333:RNA, Messenger / Q000235:genetics; D012689:Sequence Homology, Nucleic Acid; D013601:T-Lymphocytes / Q000502:physiology*; D014961:X-Ray Diffraction
D002630:Chemotactic Factors; D016209:Interleukin-8; D007378:Interleukins; D012333:RNA, Messenger; D010978:Platelet Factor 4; D004247:DNA