Subcellular localization of casein kinase I.
An anti-yeast CKI antiserum was shown to cross-react with CKI isolated from Krebs II mouse ascites tumour cells. The mammalian CKI showed virtually the same molecular mass (app. 45 kDa) as the yeast enzyme. By immunofluorescence it could be shown that CKI is preferably located in the nucleolus.
Grankowski
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Department of Molecular Biology, Maria Curie-Sklodowska University, Lublin, Poland.
Issinger
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OG
D000818:Animals; D000906:Antibodies / Q000302:isolation & purification; D002287:Carcinoma, Krebs 2 / Q000201:enzymology; D047388:Casein Kinases; D002460:Cell Line; D002846:Chromatography, Affinity; D005455:Fluorescent Antibody Technique; D005910:Glioma; D006801:Humans; D007118:Immunoassay; D051379:Mice; D008970:Molecular Weight; D011494:Protein Kinases / Q000032:analysis* / Q000276:immunology / Q000302:isolation & purification; D012441:Saccharomyces cerevisiae / Q000201:enzymology; D014407:Tumor Cells, Cultured / Q000201:enzymology
D000906:Antibodies; D011494:Protein Kinases; D047388:Casein Kinases