[Mammalian plasma proteins bindings with single-stranded DNA; their effect on DNA polymerization and degradation reactions].
A number of physicochemical properties of blood plasma proteins of mice and piglets which display their primary affinity to single-stranded DNA are studied. These proteins exert an activating effect on DNA-polymerase alpha from the Ehrlich ascites carcinoma and an inhibitory effect on the venom phosphodiesterase. A comparison of properties of the proteins under study with those of antibodies to the single-stranded DNA described in the literature permits supposing an identity of these proteins.
Novoradovskaia
N A
NA
Koterov
A N
AN
D000818:Animals; D000974:Antibodies, Antinuclear / Q000097:blood / Q000378:metabolism*; D001798:Blood Proteins / Q000378:metabolism*; D002286:Carcinoma, Ehrlich Tumor / Q000201:enzymology; D004257:DNA Polymerase II / Q000378:metabolism; D004277:DNA, Single-Stranded / Q000097:blood / Q000276:immunology / Q000378:metabolism*; D004789:Enzyme Activation; D007770:L-Lactate Dehydrogenase / Q000378:metabolism; D051379:Mice; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism; D013552:Swine
D000974:Antibodies, Antinuclear; D001798:Blood Proteins; D004277:DNA, Single-Stranded; C035357:SS-B antibodies; D007770:L-Lactate Dehydrogenase; D004257:DNA Polymerase II; D010727:Phosphoric Diester Hydrolases
Belki plazmy krovi mlekopitaiushchikh, sviazyvaiushchiesia s odnotsepochechnoĭ DNK; vliianie na reaktsii polimerizatsii i degradatsii DNK.