[Acute retinal necrosis--a herpetic retinitis?].
Acute retinal necrosis (ARN) is characterized by unilateral or bilateral severe vaso-occlusive retinitis. In a large number of cases the patients become blind in the affected eyes as a direct result of the acute inflammation or the subsequent retinal detachment. The etiology is poorly understood; herpesvirus-induced vasculitis is presumed and has been demonstrated by some authors. However, the author's own investigations in seven patients show that even vitreous biopsy reveals a herpetic origin only in a minority of cases. Intravenous treatment with acyclovir and steroids prevented progression of the retinitis but did not reduce the risk of retinal detachment.
Nasemann
J E
JE
Augenklinik, Universität München.
D000212:Acyclovir / Q000008:administration & dosage; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D005260:Female; D005451:Fluorescein Angiography; D014645:Herpesvirus 3, Human / Q000276:immunology; D006801:Humans; D007635:Keratitis, Dendritic / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment / Q000175:diagnosis; D015882:Retinal Necrosis Syndrome, Acute / Q000175:diagnosis* / Q000188:drug therapy; D012173:Retinitis / Q000175:diagnosis* / Q000188:drug therapy; D018139:Simplexvirus / Q000276:immunology
D000914:Antibodies, Viral; D000212:Acyclovir
Die akute Retinanekrose--eine herpetische Retinitis?