Diffusion-controlled ligand binding to spheres partially covered by receptors: an effective medium treatment.
An effective medium treatment is used to extend Berg and Purcell's theory of diffusion-controlled ligand binding to a sphere partially covered by receptors. This treatment takes into account more completely the effects of interference between receptors. The results are in excellent agreement with computer simulations by Northrup.
Zwanzig
R
R
Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892.
D003198:Computer Simulation; D004058:Diffusion; D008024:Ligands; D008433:Mathematics; D008954:Models, Biological; D011956:Receptors, Cell Surface / Q000378:metabolism*
D008024:Ligands; D011956:Receptors, Cell Surface