Thrombotic thrombocytopenic purpura in a patient with AIDS.
Thrombotic thrombocytopenic purpura (TTP) has only recently been documented in association with human immunodeficiency virus infection. The authors present the clinical, laboratory, and pathologic features of a unique case of secondary thrombotic thrombocytopenic purpura occurring in a patient with AIDS, including the immunohistologic characterization of the vascular thrombi. They also review 12 previously reported cases of thrombotic thrombocytopenic purpura associated with human immunodeficiency virus infection.
Department of Pathology, Cleveland Clinic Foundation, One Clinic Center, Ohio 44195.
G H
GH
Segal
R R
RR
Tubbs
N B
NB
Ratliff
M L
ML
Miller
D L
DL
Longworth
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000473:pathology; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011697:Purpura, Thrombotic Thrombocytopenic / Q000150:complications* / Q000473:pathology