Ocular anomalies in fragile X syndrome.
Fragile X (fra[X]) syndrome is a newly discovered, but relatively common, genetic disorder with an estimated frequency of 1:1000. Several ocular dysfunctions may be associated with this syndrome, but there are few articles that fully report on these. A review of this genetic disorder is provided, as well as a discussion of a case review of a family with three siblings with fragile X syndrome. Since this disorder is the most common familial cause of mental retardation, is second only to Down's syndrome as a genetic cause for mental retardation, and may play a significant role in learning disabilities, the eye care practitioner should be aware of its importance.
Illinois College of Optometry, Chicago 60616.
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Maino
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Schlange
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Maino
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Caden
D000328:Adult; D002648:Child; D005128:Eye Diseases / Q000209:etiology*; D005260:Female; D005600:Fragile X Syndrome / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D006801:Humans; D007223:Infant; D008297:Male; D001523:Mental Disorders / Q000209:etiology; D012729:Sex Chromosome Aberrations