Seven day metronidazole versus single dose tinidazole as therapy for nonspecific vaginitis.
A comparative study of the treatment of nonspecific vaginitis was carried out in 171 reproductive-aged women. The patients were randomly treated with either metronidazole or tinidazole (Ninety-three patients in Group I, received oral metronidazole 1 g daily for 7 days. Another 78 patients in Group II, received oral tinidazole 2 g single dose. The patients were advised to return for follow-up examinations 1-2 weeks after treatment in their nonmenstrual period. Of these, 50 patients in each group were subject to complete study. The cure rates were 92 per cent in Group I and 86 per cent in Group II. The difference was not significant statistically. The adverse drug reactions among the two groups were 22 and 8 per cent respectively. Tinidazole is another effective drug for the treatment of nonspecific vaginitis.
Department of Obstetrics & Gynaecology, Faculty of Medicine, Prince of Songkla University, Hat Yai, Thailand.
P
P
Buranawarodomkul
V
V
Chandeying
S
S
Sutthijumroon
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008795:Metronidazole / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D008875:Middle Aged; D014011:Tinidazole / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D014627:Vaginitis / Q000188:drug therapy* / Q000382:microbiology / Q000503:physiopathology
D014011:Tinidazole; D008795:Metronidazole