[Initial experience with the use of oral gadolinium-DTPA in nuclear magnetic resonance tomography of the pelvis].
The use of an oral contrast medium has so far not become a matter of routine in MR of the abdomen. In the present study the use of orally applied gadolinium-DTPA was examined in respect of tumorous diseases in the minor pelvis. 18 patients with tumours in the minor pelvis were examined before and after oral administration of gadolinium-DTPA (Gd-DTPA). 10 ml/kg body weight of a gadolinium DTPA solution were applied in a concentration of 1.0 mmol/l. T1-weighted and T2-weighted sequences were carried out before application and T1-weighted sequences after application. Oral application gadolinium-DTPA resulted in enhancing the signals of the filled intestinal portions. In 54% of the cases the sequences showed a sharper delineation between tumour and intestine. In 19% the delineation between pathological tissue and intestine on contrast examination was as well defined as in T2-weighted contrast images; in 27% of the cases oral administration of gadolinium-DTPA did not yield any additional information. No significant side effects were seen.
Hötzinger
H
H
Marienhospital I, Abteilung für Kernspintomographie, Ruhruniversität Bochum.
Salbeck
R
R
Toedt
C
C
Beyer
H K
HK
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D010051:Ovarian Neoplasms / Q000175:diagnosis; D010386:Pelvic Neoplasms / Q000175:diagnosis*; D004369:Pentetic Acid; D012004:Rectal Neoplasms / Q000175:diagnosis; D013736:Testicular Neoplasms / Q000175:diagnosis; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis; D014594:Uterine Neoplasms / Q000175:diagnosis
D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA
Erste Erfahrungen mit der Anwendung von oralem Gadolinium-DTPA bei der Kernspintomographie des kleinen Beckens.