What treatment would you advise for a 1-year-old child with chronic renal failure who has been on aluminum hydroxide as a phosphate binder for 6 months and then develops epilepsy and is found to have a grossly raised plasma aluminum concentration?
Andreoli
S P
SP
Indiana University, Riley Children's Hospital, Indianapolis.
Chesney
R W
RW
Salusky
I B
IB
Sedman
A B
AB
D000535:Aluminum / Q000097:blood*; D000536:Aluminum Hydroxide / Q000009:adverse effects* / Q000627:therapeutic use; D003676:Deferoxamine / Q000627:therapeutic use; D004827:Epilepsy / Q000139:chemically induced*; D006801:Humans; D007223:Infant; D007676:Kidney Failure, Chronic / Q000188:drug therapy / Q000378:metabolism*
D000536:Aluminum Hydroxide; D000535:Aluminum; D003676:Deferoxamine