Use of antibiotic-loaded bone cement in the management of common infections of the foot and ankle.
Antibiotic-loaded bone cement is a useful adjunct in the management of chronic osteomyelitis and in the prevention of recurrent osteomyelitis after an initial attack. Additionally, antibiotic-loaded bone cement stimulated the formation of granulation tissue in excess of that which would normally be expected. Our experience has been consistent with others' experience, which suggests that the use of antibiotic-loaded bone cement is an effective means of reducing the length of hospitalization and the cost usually associated with traditional methods in the management of bone and soft-tissue infections.
Jacobs
A M
AM
Department of Podiatric Medicine and Surgery, Deaconess Hospital, St. Louis, Missouri.
Seifert
A M
AM
Kirisits
T J
TJ
Protzel
H R
HR
D000293:Adolescent; D000328:Adult; D000842:Ankle; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001424:Bacterial Infections / Q000188:drug therapy*; D001777:Blood Coagulation; D001843:Bone Cements / Q000008:administration & dosage*; D001847:Bone Diseases / Q000188:drug therapy*; D003646:Debridement; D004304:Dosage Forms; D005534:Foot Diseases / Q000188:drug therapy*; D005839:Gentamicins / Q000008:administration & dosage; D006801:Humans; D010019:Osteomyelitis / Q000188:drug therapy*; D014182:Transplantation, Autologous
D000900:Anti-Bacterial Agents; D001843:Bone Cements; D004304:Dosage Forms; D005839:Gentamicins