A 12 kDa protein in chicken serum antigenically cross-reactive with, but unrelated to, beta 2-microglobulin.
A protein, isolated from chicken serum, showed the following beta 2-microglobulin-like properties; an apparent molecular size of 12000 Mr, predominantly beta-sheet secondary structure, and antigenic cross-reaction with human beta 2-microglobulin. However, amino acid composition analysis and partial amino acid sequence analysis showed that this molecule was not only not a beta 2-microglobulin, but was unrelated to any other known class of protein.
Warr
G W
GW
Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston 29425.
D000595:Amino Acid Sequence; D000645:Ammonium Sulfate; D000818:Animals; D001798:Blood Proteins / Q000276:immunology* / Q000302:isolation & purification; D002645:Chickens / Q000097:blood* / Q000276:immunology; D002852:Chromatography, Ion Exchange; D002942:Circular Dichroism; D003429:Cross Reactions; D004797:Enzyme-Linked Immunosorbent Assay; D008969:Molecular Sequence Data; D008970:Molecular Weight; D013057:Spectrum Analysis; D001613:beta 2-Microglobulin / Q000276:immunology*
D001798:Blood Proteins; D001613:beta 2-Microglobulin; D000645:Ammonium Sulfate