Antibacterial therapy in cystic fibrosis.
Bacterial lung infections determine the prognosis for most cystic fibrosis patients. The antibacterial therapy is difficult because of the host-bacterium interaction and altered pharmacokinetics. The new insights in the working mechanisms of antibiotics that may lead to better treatment results have been discussed, and guidelines for treatment of lung infections in cystic fibrosis patients were given.
Mouton
J W
JW
Erasmus University School of Medicine, Rotterdam, The Netherlands.
Kerrebijn
K F
KF
D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D003550:Cystic Fibrosis / Q000150:complications*; D006192:Haemophilus Infections / Q000188:drug therapy; D006193:Haemophilus influenzae; D006801:Humans; D011552:Pseudomonas Infections / Q000188:drug therapy; D012141:Respiratory Tract Infections / Q000209:etiology / Q000517:prevention & control*; D013203:Staphylococcal Infections / Q000188:drug therapy
D000900:Anti-Bacterial Agents