[Study of iron metabolism in chronic diffuse diseases of the liver].
Iron metabolism was studied in patients with chronic diffuse diseases of the liver. A sharp increase of ferritin content at the expense of its release from affected hepatocytes, and formation of antibodies to ferritin of the splenic type have been recorded in patients with cirrhosis of the liver. The observed growth of ferritin content in red blood cells can be explained by functional deficiency of red blood cells and by the presence of hemolytic process (twofold decrease of haptoglobin level). A conclusion has been made that ferritin content in the blood serum does not correlate with the total iron reserves, and serum ferritin level should be considered not as a sign of the pathologic process, but as an index of iron reserves capable of participating in metabolic processes.
A A
AA
Levina
L A
LA
Zherebtsov
M M
MM
Tsibul'skaia
Iu V
IuV
Korol'ko
A P
AP
Andreeva
Iu G
IuG
Miterev
Iu N
IuN
Tokarev
D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D005293:Ferritins / Q000737:chemistry / Q000378:metabolism*; D006521:Hepatitis, Chronic / Q000378:metabolism*; D006801:Humans; D007501:Iron / Q000737:chemistry / Q000378:metabolism*; D008099:Liver / Q000378:metabolism*; D008103:Liver Cirrhosis / Q000378:metabolism*; D008297:Male; D008875:Middle Aged
D005293:Ferritins; D007501:Iron
Izuchenie metabolizma zheleza pri khronicheskikh diffuznykh zabolevaniiakh pecheni.