[Activation of lipid peroxidation in erythrocytes during blood coagulation in vitro].
A comparative investigation of antioxidant enzyme activity and lipid hydroperoxide concentration in red blood cells of the whole and anticoagulant-containing blood of 33 donors was conducted to elucidate the causes of increasing the permeability of red blood cell membrane during blood coagulation in vitro. It has been shown that one of the causes of intensified red blood cell peroxidation during blood coagulation is a disturbed ratio of superoxide dismutase and catalase activities leading to a decrease in the antioxidant enzymatic protection.
G A
GA
Bezrukova
V I
VI
Rubin
D001777:Blood Coagulation / Q000502:physiology*; D002374:Catalase / Q000097:blood; D004912:Erythrocytes / Q000201:enzymology / Q000378:metabolism*; D006801:Humans; D006861:Hydrogen Peroxide / Q000097:blood; D066298:In Vitro Techniques; D015227:Lipid Peroxidation / Q000502:physiology*; D013482:Superoxide Dismutase / Q000097:blood
D006861:Hydrogen Peroxide; D002374:Catalase; D013482:Superoxide Dismutase
Aktivatsiia protsessov perekisnogo okisleniia lipidov v éritrotsitakh pri svertyvanii krovi in vitro.