[The immunologic situation of the placenta and its significance for disorders in early pregnancy].
Reference is made in numerous recent immunological studies to immunological mechanisms which were found to play a role in acceptance of pregnancy or habitual abortions. The most important theories likely to offer explanations for these phenomena are reviewed in some detail, including hormonal immunosuppression, immunologic-anatomic barrier at the placenta as well as blocking factors and anti-sperm antibodies. Molar pregnancy is associated with a particular immunological situation. None of the theories mentioned can be preferred, for the time being, to explain acceptance of normal pregnancy or the causes of recurrent spontaneous abortions.
Horn
L C
LC
Institut für Pathologische Anatomie, Bereichs Medizin Karl-Marx-Universität Leipzig, DDR.
Rosenkranz
M
M
Bilek
K
K
D000026:Abortion, Habitual / Q000276:immunology*; D000906:Antibodies / Q000276:immunology; D001667:Binding, Competitive; D005260:Female; D006801:Humans; D007108:Immune Tolerance; D008297:Male; D010920:Placenta / Q000276:immunology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology*; D013094:Spermatozoa / Q000276:immunology
D000906:Antibodies
Zur immunologischen Situation an der Plazenta und zu ihrer Bedeutung für Störungen in der Frühschwangerschaft.