Cardiac failure in coronary heart disease.
Cardiac failure, which used to be rare in coronary heart disease, is now its most common complication. Coronary heart disease can cause or appear as cardiac failure through one or more of 12 mechanisms: acute myocardial infarction, acute reversible ischemia, right ventricular dysfunction, cardiogenic shock, acute mitral regurgitation, ventricular septal perforation, cardiac free wall rupture, ischemic cardiomyopathy, ventricular aneurysm, coexisting diseases, iatrogenesis, and pseudoheart failure. An understanding of the responsible mechanism or mechanisms is essential not only for appropriate treatment but also for prognostication. Various therapeutic modalities, both medical and surgical, should be able to improve not only symptoms but also survival. Current efforts in the management of patients with cardiac failure as a result of coronary heart disease should be aimed at prevention, both primary and secondary.
Department of Medicine, George Washington University School of Medicine and Health Sciences, Washington, DC.
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D001696:Biomechanical Phenomena; D002303:Cardiac Output, Low / Q000209:etiology* / Q000628:therapy; D003327:Coronary Disease / Q000209:etiology* / Q000503:physiopathology; D005260:Female; D006322:Heart Aneurysm / Q000150:complications; D006342:Heart Rupture, Post-Infarction / Q000150:complications; D006343:Heart Septal Defects / Q000150:complications; D006801:Humans; D008297:Male; D008944:Mitral Valve Insufficiency / Q000150:complications; D009203:Myocardial Infarction / Q000150:complications; D011379:Prognosis; D012770:Shock, Cardiogenic / Q000209:etiology