[Glucocorticoids in asthmatic crisis in children].
Systemic corticosteroids are misused in children with acute asthma. Their misuse is one of the factors responsible for the recent increase in asthma mortality. Since 1980, 10 of 12 double blind randomized clinical trials have shown the beneficial effects of corticosteroids in acute asthma incompletely responsive to bronchodilatators. The value of early course-high dose-short term corticosteroid therapy is emphasized. The side effects of such short corticosteroid courses are minimal and transient. Management of asthma should be reconsidered if steroid courses are too frequent.
Service de Pédiatrie, Hôpital Ambroise-Paré, Boulogne.
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Bidat
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Scheinmann
D001249:Asthma / Q000188:drug therapy* / Q000401:mortality; D002648:Child; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D013224:Status Asthmaticus / Q000188:drug therapy* / Q000517:prevention & control
D005938:Glucocorticoids
Les glucocorticoïdes dans la crise d'asthme de l'enfant.