Milurit's place in therapy.
After a brief review of the history of allopurinol therapy the mechanism of action, interactions with other drugs, side-effects, indications and contra-indications of Milurit (100 mg allopurinol per tab, EGIS Pharmaceuticals, Budapest) in adults and children, and the dosage of the drug have been discussed. It has been emphasized that allopurinol is an effective but not the sole means in the treatment of clinical processes accompanied by hyperuricaemia. The adequate choice of a drug in a given indication field not only improves the therapeutic results but prevents the development of one part of the side-effects such as among others the severe allopurinol hypersensitivity syndrome which often has a lethal outcome.
Department of Rheumatology and Physiotherapy, Postgraduate Medical School, Budapest.
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B
Gömör
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Szebenyi
D000493:Allopurinol / Q000008:administration & dosage / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D004347:Drug Interactions; D006801:Humans; D014527:Uric Acid / Q000097:blood*
D014527:Uric Acid; D000493:Allopurinol