[A case report of an acute myelogenous leukemia (FAB M1) with Klinefelter's syndrome].
Reported is the second documented case in Japan of acute leukemia with Klinefelter's syndrome. The patient, a 52-year-old male, was admitted to hospital on July 9, 1983, after complaining of a fever and general malaise. The hematological examinations revealed a WBC count of 14,300/cmm with 32% being leukemic cells. Bone marrow aspiration disclosed a nucleated cell count of 687,000/cmm with 41.6% being leukemic cells consisting of myeloblasts. The endocrinic laboratory data showed a high level of urine gonadotropin and chromosomal studies revealed a 47,XXY karyotype. A diagnosis of acute myelogenous leukemia (M1) with Klinefelter's syndrome thus was derived from these findings.
1st Dept. of Int. Med., Kyoto Prefectural Univ. of Med.
T
T
Mizuno
M
M
Ozawa
Y
Y
Oyamada
T
T
Takegami
H
H
Horiuchi
N
N
Maruo
Y
Y
Kobayashi
M
M
Kondo
H
H
Nishigaki
S
S
Misawa
D006801:Humans; D007111:Immunity, Cellular; D007621:Karyotyping; D007713:Klinefelter Syndrome / Q000150:complications* / Q000235:genetics / Q000276:immunology; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008297:Male; D008875:Middle Aged