[Fulminating cryptococcal meningoencephalitis. An anatomo-clinical case].
We report a case of cryptococcal meningoencephalitis in a 52 year-old man. The patient had complained of headache and drowsiness for a few hours before he became comatose with a bilateral sixth cranial nerve palsy. The cerebrospinal fluid contained less than one lymphocyte per cubic millimeter, a low glucose level (0.20 g/l) and numerous Cryptococcus neoformans encapsulated yeasts. A neuropathological study showed that the cortex and midbrain were involved. To our knowledge, such an acute case with death within the first 20 hours has not yet been reported.
Service de neurologie, Centre Hospitalier Universitaire, Lille.
P
P
Vermersch
D
D
Leys
M
M
Lorthioir
F
F
Pasquier
I
I
Krivosic
H
H
Petit
D001921:Brain / Q000473:pathology; D003453:Cryptococcosis / Q000134:cerebrospinal fluid / Q000473:pathology*; D006801:Humans; D008297:Male; D008590:Meningoencephalitis / Q000134:cerebrospinal fluid / Q000473:pathology*; D008875:Middle Aged; D013997:Time Factors
Cryptococcose neuro-méningée foudroyante. Un cas anatomo-clinique.