Potential inhibitors of platelet aggregation from plant sources, V. Anthraquinones from seeds of Cassia obtusifolia and related compounds.
Three anthraquinone glycosides, gluco-obtusifolin [11], gluco-chryso-obtusin [15], and gluco-aurantioobtusin [13], were found to be platelet anti-aggregatory constituents of seeds of Cassia obtusifolia. Various other anthraquinone analogues were also tested, and their structure-activity relationships are discussed.
Yun-Choi
H S
HS
Natural Products Research Institute, Seoul National University, Korea.
Kim
J H
JH
Takido
M
M
D000818:Animals; D000880:Anthraquinones / Q000032:analysis*; D002366:Cassia / Q000032:analysis*; D010946:Plants, Medicinal; D010975:Platelet Aggregation Inhibitors / Q000302:isolation & purification*; D051381:Rats; D012639:Seeds / Q000032:analysis
D000880:Anthraquinones; D010975:Platelet Aggregation Inhibitors