[Evaluation of the efficacy of amino 4-quinolones in a chemoresistant zone. Proposals for new therapeutic schemes].
The authors compare the respective therapeutic efficiency of chloroquine and amodiaquine in the treatment of Plasmodium falciparum malaria fever in urban dispensaries. Chloroquine has a constant rate of efficiency, whatever dosage and duration of treatment be and should be saved for home presumptive treatment of malaria fever. Amodiaquine at a dose of 35 mg/kg in 3 days leads to a noticeable clinical success (96.5 p.c.). It should be selected as drug of first to treat any malaria fever case biologically confirmed, in urban dispensaries.
Hengy
C
C
Biologiste des Hôpitaux, Organisation de Coordination pour la lutte contre les Grandes Endémies en Afrique Centrale (O.C.E.A.C.), Yaoundé, Cameroun.
Gazin
P
P
Eberle
F
F
Jambou
R
R
Louis
J P
JP
D000655:Amodiaquine / Q000008:administration & dosage / Q000627:therapeutic use*; D000818:Animals; D002163:Cameroon; D002738:Chloroquine / Q000008:administration & dosage / Q000627:therapeutic use*; D002985:Clinical Protocols / Q000592:standards*; D004351:Drug Resistance; D006801:Humans; D008288:Malaria / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy*; D010594:Pharmacies; D010963:Plasmodium falciparum; D014505:Urban Population
D000655:Amodiaquine; D002738:Chloroquine
Evaluation de l'efficacité des amino-4 quinoléines en zone de chimioresistance: proposition de nouveaux schémas thérapeutiques.