Effects of growth hormone in short, slowly growing children without growth hormone deficiency. Australasian Paediatric Endocrine Group.
The aim of the study was to measure the real effect of growth hormone (GH) treatment compared to the effect of placebo, since a placebo effect has been shown in other studies involving interventional growth therapy. Changes in height velocity and insulin-like growth factor I (IGF-I), relative to pretreatment variables, were examined during a 12-month, double-blind study.
Royal Alexandra Hospital for Children, Sydney, Australia.
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Cowell
D000293:Adolescent; D001827:Body Height / Q000187:drug effects*; D002648:Child; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D005260:Female; D006128:Growth / Q000187:drug effects*; D013006:Growth Hormone / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use*; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000032:analysis; D008297:Male; D016032:Randomized Controlled Trials as Topic
D007334:Insulin-Like Growth Factor I; D013006:Growth Hormone