Chemotherapy for squamous cell carcinoma of the head and neck: an overview.
Chemotherapy is being utilized to treat patients with recurrent tumors and advanced squamous cell carcinoma of the head and neck. Current treatment modalities utilized include intra-arterial chemotherapy, simultaneous and sequential chemotherapy and radiation therapy, and neoadjuvant chemotherapy. Each of these modes of treatment, as well as pharmacology of squamous cell-active chemotherapeutic agents, will be addressed in this review.
Espinola
T E
TE
Dept of Otolaryngology Head & Neck Surgery, Tulane Medical Center, New Orleans, LA.
White
J A
JA
D002294:Carcinoma, Squamous Cell / Q000188:drug therapy* / Q000532:radiotherapy; D002945:Cisplatin / Q000627:therapeutic use; D003131:Combined Modality Therapy; D006258:Head and Neck Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use; D012008:Recurrence
D002945:Cisplatin; D008727:Methotrexate