Eosinophilic granuloma. The management of solitary lesions of bone.
Solitary eosinophilic granuloma (EG) lesions of bone can represent diagnostic and treatment dilemmas for the orthopedic surgeon. A retrospective review of one institution's experience with isolated EG skeletal lesions over a 30-year period was undertaken. Solitary lesions responded well to most treatment modalities (e.g., curettage, excision, and irradiation) and infrequently resulted in functional impairment. While EG involvement in bone can be a manifestation of a systemic histiocytosis, single-focus skeletal involvement appears to be a benign pathophysiologic process.
Section of Orthopaedic Surgery, University of Michigan, Ann Arbor.
P E
PE
Greis
F M
FM
Hankin
D001847:Bone Diseases / Q000000981:diagnostic imaging* / Q000532:radiotherapy / Q000601:surgery; D002648:Child; D003475:Curettage; D003646:Debridement; D004803:Eosinophilic Granuloma / Q000000981:diagnostic imaging* / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D011859:Radiography; D012189:Retrospective Studies