[The value of cytological grading of prostatic adenocarcinoma. Comparison of the clinical state, the Gleason score and grade in 69 cases].
During a two-year period, 69 positive prostatic fine-needle cyto-aspirates were selected for a comparison between the cytological grade and the clinical data, and also with the Gleason score and grade obtained with needle-biopsy. The cytological grade is independent of stage, except for grade III that indicates an advanced tumor (T3-T4). On the other hand, the cytological grade provides valuable indications on the histopathological differenciation according to Gleason, with no grade II inferior to Gleason score 5, and no grade III inferior to Gleason 7. 90% of cytological grades III are Gleason grade 4. According to recent studies, we believe that the cytological grade I is related to invasive or in-situ carcinoma, but also to high-grade intra-ductal dysplasia. Thus, it is not surprising to find no correlation between grade I and the clinical status, nor between grade I and the Gleason score and grade, though grade I (or DIC 3) has a good diagnostic value.
Laboratoire de cytologie, hôpital Albert-Michallon, Grenoble.
E
E
Piaton
J
J
Mouriquand
N
N
Berger
P
P
Mouriquand
D
D
Seigneurin
M
M
Devonec
P
P
Perrin
D000230:Adenocarcinoma / Q000145:classification / Q000175:diagnosis / Q000473:pathology*; D001707:Biopsy, Needle; D006801:Humans; D008297:Male; D009367:Neoplasm Staging / Q000379:methods*; D011471:Prostatic Neoplasms / Q000145:classification / Q000175:diagnosis / Q000473:pathology*
Valeur du grade cytologique dans l'adénocarcinome prostatique. Comparison avec le stade clinique, le score et le grade de Gleason dans 69 cas.