A study of estrogen and progesterone receptors in spider telangiectasias of the lower extremities.
There is an association of some vascular tumors with estrogen receptors and an association of vascular telangiectasias with high levels of circulating estrogen. Because of this, a study of patients with lower extremity starburst telangiectasias and predisposing factors associated with hyperestrogenemic and hyperprogesteronemic states was undertaken in order to look for estrogen and progesterone receptors in biopsy specimens of lower extremity telangiectasias noted to arise in this setting. Contrary to expected results, using immunocytochemical techniques, no patient in this study was found to have estrogen or progesterone receptors present in their lower extremity telangiectasias. Possible explanations for these results are discussed.
Division of Dermatology, Cornell University Medical College, Ithaca, New York.
N S
NS
Sadick
G W
GW
Niedt
D000328:Adult; D003278:Contraceptives, Oral, Hormonal / Q000009:adverse effects; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007866:Leg / Q000098:blood supply*; D008875:Middle Aged; D009383:Neoplasms, Vascular Tissue / Q000150:complications; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular; D011960:Receptors, Estrogen / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis*; D012680:Sensitivity and Specificity; D013684:Telangiectasis / Q000150:complications / Q000209:etiology / Q000378:metabolism*
D003278:Contraceptives, Oral, Hormonal; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone