Mutations that alter the primary structure of type I collagen. The perils of a system for generating large structures by the principle of nucleated growth.
Department of Biochemistry and Molecular Biology, Jefferson Institute of Molecular Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
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D000818:Animals; D003094:Collagen / Q000096:biosynthesis / Q000235:genetics* / Q000648:ultrastructure; D030342:Genetic Diseases, Inborn / Q000235:genetics; D006801:Humans; D009154:Mutation; D011347:Procollagen / Q000235:genetics; D011487:Protein Conformation
D011347:Procollagen; D003094:Collagen