[Roxithromycin versus doxycycline in the treatment of cervicitis. Prospective randomized multicenter study under practice-related conditions].
In a prospective randomized multicenter study Roxithromycin 150 mg or Doxycycline 100 mg was given b.i.d. p.o. for ten days to women with clinically diagnosed cervicitis. All women were seen as outpatients by one of eight licensed gynecologists in their private office in the Essen city area. With a cure and improvement rate of 100% in those women who completed therapy, Roxithromycin (n = 106) was as effective as Doxycycline (n = 104; 98%). At 90% Roxithromycin was as well tolerated as Doxycycline at 93%. Both drugs were clinically and microbiologically effective in eradicating Chlamydia trachomatis.
Zentrum für Frauenheilkunde, Universitätsklinikum Essen.
U B
UB
Hoyme
M
M
Alimi
H U
HU
Feldmann
H
H
Gerlach
U
U
Keuter
H J
HJ
Marks
M
M
Moayer
A F
AF
Salih
A E
AE
Schindler
H J
HJ
Stangier
D000328:Adult; D004318:Doxycycline / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D015337:Multicenter Studies as Topic; D011446:Prospective Studies; D011897:Random Allocation; D015575:Roxithromycin / Q000627:therapeutic use*; D002575:Uterine Cervicitis / Q000175:diagnosis / Q000188:drug therapy*
D015575:Roxithromycin; D004318:Doxycycline
Roxithromycin versus Doxycyclin in der Zervizitisbehandlung. Prospektive randomisierte Multicenterstudie unter praxisbezogenen Bedingungen.