[The use of immobilized and native proteolytic enzymes in treating inflammatory periodontal diseases].
.1% solution of native terrilytin, a proteolytic enzyme, and 5% profezyme, an immobilized enzyme, were used in the treatment of periodontal inflammations. To enhance the efficacy of enzyme therapy, the latter agent was combined with an antiseptic and pyrimidine-based methychlozyme paste including 5% of profezyme, 0.2% of chlorohexidine bigluconate, 0.2% of methyluracil, 30% of glycerin, and zinc oxide 74.6%. Use of immobilized and native proteolytic enzymes in therapy of patients with gingivitis and periodontitis permitted reducing the number of sessions 1.5-fold. Multiple-modality treatment was conducive to prolongation of the process remission up to 2 years in 52.31% of patients whereas in conventional therapy such remissions could be achieved in only 20%.
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Chuchmaĭ
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Zubachik
D000328:Adult; D002908:Chronic Disease; D003131:Combined Modality Therapy; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D004800:Enzymes, Immobilized / Q000627:therapeutic use*; D005891:Gingivitis / Q000188:drug therapy; D006801:Humans; D010447:Peptide Hydrolases / Q000627:therapeutic use*; D010518:Periodontitis / Q000188:drug therapy*; D013997:Time Factors
D004800:Enzymes, Immobilized; D010447:Peptide Hydrolases
Primenenie immobilizovannykh i nativnykh proteoliticheskikh fermentov pri lechenii vospalitel'nykh zabolevaniĭ parodonta.