[The results of a clinical study of the preparation hydrazine sulfate].
The paper discusses results of a cooperative study of effectiveness of hydrazine sulfate therapy in 740 patients with primary advanced, recurrent and metastatic solid tumors and malignant lymphomas who had failed all other treatment modalities. Both objective response and symptomatic effect were assessed. Objective response was observed in neuroblastoma, recurrent desmoid, Hodgkin's disease, lung cancer, fibrosarcoma and other tumors. Since hydrazine sulfate provided relief of a wide spectrum of cancer symptoms, it may be recommended for patients with end-stage cancer.
Filov
V A
VA
Danova
L A
LA
Gershanovich
M L
ML
Ivin
B A
BA
Dement'eva
N P
NP
Breĭvis
P V
PV
Ragaĭshene
V P
VP
Kas'ianenko
I V
IV
Lisitsa
A M
AM
Mindlin
S S
SS
D000293:Adolescent; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D006834:Hydrazines / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D015337:Multicenter Studies as Topic; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy; D009369:Neoplasms / Q000188:drug therapy; D012074:Remission Induction; D013608:Tablets, Enteric-Coated; D013997:Time Factors
D000970:Antineoplastic Agents; D006834:Hydrazines; D013608:Tablets, Enteric-Coated; C029424:hydrazine
Rezul'taty klinicheskogo izucheniia preparata gidrazinsul'fat.