Immunoreactive beta-endorphin, cortisol, and growth hormone plasma levels in obsessive-compulsive disorder.
Basal morning plasma levels of immunoreactive-beta-endorphin (ir-beta-EP), cortisol, and growth hormone (GH) were assessed in 13 obsessive-compulsive disorder (OCD) patients in comparison to 20 healthy controls. All subjects were drug free for at least 1 year. The mean plasma level of ir-beta-EP was significantly lower (36%) in the OCD patients when compared with the control subjects. The decrease in ir-beta-EP was not accompanied by alteration in cortisol and GH plasma levels.
Hasharon Hospital, Petah Tiqva, Israel.
R
R
Weizman
I
I
Gil-Ad
H
H
Hermesh
H
H
Munitz
Z
Z
Laron
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D005260:Female; D013006:Growth Hormone / Q000097:blood*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000097:blood*; D011863:Radioimmunoassay; D012737:Sex Factors; D001615:beta-Endorphin / Q000097:blood*
D001615:beta-Endorphin; D013006:Growth Hormone; D006854:Hydrocortisone