[Clinical study on xintongkang capsule in treating angina pectoris of coronary heart disease].
Two hundred and sixty seven cases of angina pectoris of coronary heart disease (male 152, female 115, age 41--79) were studied. Among these, 195 cases were patients with effort angina, 72 cases with non-effort angina. Double blind stratified randomized grouping, differentiation- syndromes treatment of TCM and self-control observation methods were applied. The results showed that total effective rate was 93.3% for angina pectoris in the treatment group. While control group which were treated by persantin and aspirin was 54.7% (P less than 0.001). For resting ECG evaluation total effective rates were 52.78% and 13.51% respectively. The ECG exercise testing (protocol Bruce) and dynamic ECG also showed the results similar to that of resting ECG. According to differentiation-syndromes treatment of TCM. The effect of Xintongkang capsule on simple stagnation of Qi and stasis of blood, or combined with deficiency of Qi, or combined with deficiency of Yin was better than other symptoms. The effect of Xintongkang capsule initiated in the second week after oral medicine, peak response occurring in the fourth week, and it trend to the stability in the eighth week. There was no harmful effect to heart, liver, kidney and blood. No allergic reactions were found in this observation.
First Affiliated Hospital of Nanjing Medical College.
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Wu
D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000188:drug therapy*; D002214:Capsules; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D002214:Capsules; D004365:Drugs, Chinese Herbal