Cone dystrophy and supernormal dark-adapted b-waves in the electroretinogram.
A male patient suffering from cone dystrophy was followed over 9 years. In addition to the typical clinical and electrophysiologic signs, supernormal b-waves were found in the dark-adapted electroretinogram. Our case is compared with 12 similar patients described in the literature. Our patient differed from the other patients in the following aspects: he was male and had a congenital stationary disease with a small pigment epithelial scar in the left eye only and no other fundus changes up to the age of 22 years. He did not complain of night blindness. The dark-adapted electroretinogram of our patient showed a normal b-wave threshold with increased b-wave amplitudes and markedly prolonged b-wave latencies and implicit times. This combination of signs has not been reported to date in any other patient and points towards a postreceptoral defect of the interneuronal connection.
Zentrum für Augenheilkunde, Universität Essen, Federal Republic of Germany.
M H
MH
Foerster
U
U
Kellner
A
A
Wessing
D000293:Adolescent; D003117:Color Vision Defects / Q000209:etiology; D003623:Dark Adaptation; D004596:Electroretinography; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012174:Retinitis Pigmentosa / Q000150:complications / Q000503:physiopathology*; D014792:Visual Acuity