The role of mesangial cells in glomerular pathology.
The glomerular mesangial cell has become increasingly recognized as a multifunctional cell capable of mediating glomerular disease. This article reviews recent findings regarding the biology of these cells, and the relevance that these findings may have for our understanding of glomerular pathology.
School of Pathology, University of New South Wales, Sydney.
N J
NJ
Hawkins
D
D
Wakefield
J A
JA
Charlesworth
D000818:Animals; D002455:Cell Division; D002478:Cells, Cultured; D005920:Glomerular Mesangium / Q000166:cytology* / Q000378:metabolism / Q000503:physiopathology; D005921:Glomerulonephritis / Q000378:metabolism* / Q000503:physiopathology; D006023:Glycoproteins / Q000378:metabolism; D006801:Humans; D007375:Interleukin-1 / Q000096:biosynthesis; D010100:Oxygen / Q000378:metabolism; D010587:Phagocytosis / Q000502:physiology; D010972:Platelet Activating Factor / Q000502:physiology; D010982:Platelet-Derived Growth Factor / Q000096:biosynthesis; D011453:Prostaglandins / Q000096:biosynthesis
D006023:Glycoproteins; D007375:Interleukin-1; D010972:Platelet Activating Factor; D010982:Platelet-Derived Growth Factor; D011453:Prostaglandins; D010100:Oxygen