[Therapeutic aspects of salmonellosis in AIDS].
For the HIV positive patient, salmonella raises numerous epidemiological and therapeutic problems. This microorganism, quite common before zidovudine therapy, seems to have diminished since this antiviral also has an antibiotic activity against salmonella. When bacterial contamination occurs, the decreased immunitary activity might play a role, but hypochloridria, frequently afflicting these patients, might also be involved. Therapeutically, antibiotics with high intramacrophagic diffusion yield excellent results and limit the incidence of recurrence. The effect of gamma interferon is well documented in vitro. However, the efficacy of these quinolones does not lead us to believe that it is the treatment of choice.
Service des Maladies Infectieuses et Tropicales, Hôpital de l'Archet, Nice, France.
P
P
Dellamonica
V
V
Mondain
E
E
Bernard
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D051379:Mice; D009894:Opportunistic Infections / Q000188:drug therapy / Q000209:etiology*; D012480:Salmonella Infections / Q000188:drug therapy* / Q000209:etiology; D015215:Zidovudine / Q000627:therapeutic use*
D000900:Anti-Bacterial Agents; D015215:Zidovudine
Aspect thérapeutique des salmonelloses au cours du SIDA.