Does protein phosphorylation play a role in translational control by eukaryotic aminoacyl-tRNA synthetases?
In addition to their primary role in tRNA charging, aminoacyl-tRNA synthetases can regulate protein synthesis in eukaryotic cells. Although the phosphorylation of these enzymes themselves has little effect on their catalytic activity, there may be a role for protein phosphorylation in mediating their regulatory effects.
Clemens
M J
MJ
Department of Cellular and Molecular Sciences, St George's Hospital Medical School, London, UK.
D000222:Adaptation, Physiological; D000604:Amino Acyl-tRNA Synthetases / Q000378:metabolism*; D010766:Phosphorylation; D014176:Protein Biosynthesis
D000604:Amino Acyl-tRNA Synthetases