Molecular mechanisms of diuretic agents.
Recent identification of the renal epithelial cell ion transporters inhibited by diuretics allows physicians to select appropriate types and doses of diuretics. The desirable and undesirable clinical consequences of these molecular mechanisms of action can also be predicted.
Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232.
J
J
Breyer
H R
HR
Jacobson
D000042:Absorption; D000818:Animals; D001692:Biological Transport / Q000187:drug effects; D004232:Diuretics / Q000494:pharmacology*; D006801:Humans; D007684:Kidney Tubules / Q000187:drug effects* / Q000378:metabolism; D008954:Models, Biological; D014882:Water-Electrolyte Balance / Q000187:drug effects*
D004232:Diuretics