[Electron microscopy morphometry of cells of patients with different immunologic subvariants of acute lymphoblastic leukemia].
By the electron-microscopic morphometry it is determined that the cells of acute lymphoblastic leukemia (ALL) with synonymous immunological phenotype also have the same submicroscopic structure and are characterized by definite morphometric features which distinguish them from lymphoblasts of other subvariants. These results indicate that the electron-microscopic morphometry is one of the criteria for precise identification of leukemic cells. Besides, the similarity of the morphometric features of leukemic cells of the concrete lineage with the synonymous differentiation status confirm their lineage fidelity.
L V
LV
Muskhlishvili
M V
MV
Mandzhgaladze
A T
AT
Shengelaia
D000293:Adolescent; D000911:Antibodies, Monoclonal; D000943:Antigens, Differentiation / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D005455:Fluorescent Antibody Technique; D000949:Histocompatibility Antigens Class II / Q000032:analysis; D006801:Humans; D007223:Infant; D008854:Microscopy, Electron; D010641:Phenotype; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000145:classification / Q000276:immunology / Q000473:pathology*
D000911:Antibodies, Monoclonal; D000943:Antigens, Differentiation; D000949:Histocompatibility Antigens Class II
Elektronno-mikroskopicheskaia morfometriia kletok bol'nykh razlichnymi immunologicheskimi podvariantov ostrogo limfoblastnogo leĭkoza.