Non-invasive ovarian carcinoma.
The subset of ovarian epithelial tumors that is morphologically carcinoma, but has not yet shown any stromal invasion, is discussed. It is emphasized that metastasis is a function of invasive tumors, and that the spread of a noninvasive lesion cannot be explained by the usual concepts of metastasis. The multicentricity of peritoneal origin of ovarian epithelial tumors is a far more likely reason for morbidity and mortality, and is inescapable when the ovaries contain no lesion, when they contain a lesion that is noninvasive, or when the ovaries have been surgically removed.
Department of Pathology, Brown University, Providence, Rhode Island.
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Lauchlan
D002277:Carcinoma / Q000401:mortality / Q000473:pathology*; D005260:Female; D006801:Humans; D009361:Neoplasm Invasiveness; D010051:Ovarian Neoplasms / Q000401:mortality / Q000473:pathology*