[The serum beta-2-microglobulin values in drug addicts with persistent generalized lymphadenopathy].
Serum beta 2-microglobulin levels (beta-2-M) were studied in 150 drug addicts, 50 of them asymptomatic carriers of anti HIV-1 antibodies, 50 symptomatic carriers with persistent generalized lymphadenopathy (P.G.L.) and 50 serum negative patients who had been living in a closed community for at least 2 years. The results showed increased beta-2-M in 24 P.G.L. patients (48%), in 6 of the asymptomatic serum positive cases (12%) and in 3 of the serum negative subjects (6%). No such increase was found in the selected control group. Statistical analysis using the chi-square test and one-way variance analysis gave a significant result. The data suggest that increased serum beta-2-M is essentially linked to the presence of P.G.L.
II Facoltà di Medicina, Università degli Studi di Napoli.
R
R
De Mercato
E
E
Perna
G
G
Oriani
V
V
Siciliano
V
V
Iovinella
R
R
Ciampi
A
A
Bassi
R
R
Tagliaferro
D000386:AIDS-Related Complex / Q000097:blood* / Q000453:epidemiology; D000163:Acquired Immunodeficiency Syndrome / Q000097:blood / Q000453:epidemiology; D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D002353:Carrier State / Q000097:blood / Q000453:epidemiology; D016009:Chi-Square Distribution; D006679:HIV Seropositivity / Q000097:blood / Q000453:epidemiology; D006801:Humans; D008297:Male; D015819:Substance Abuse, Intravenous / Q000097:blood*; D001613:beta 2-Microglobulin / Q000032:analysis*
D001613:beta 2-Microglobulin
Studio dei valori sierici di beta 2-microglobulina in tossicodipendenti affetti da linfoadenopatia persistente generalizzata.