Operative therapy in metastases and primary tumors of the spine.
Benign and primary malignant tumors of the spine require a ventral procedure to remove the tumor and to stabilize the spine. Experience in the last years has shown that sole laminectomy in children can no longer be recommended. An instrumentation of the spine to prevent kyphosis must be performed. The rate of pseudarthrosis was of course, high when the kyphosis was treated by an exclusive dorsal instrumentation. In patients with severe kyphosis a combined procedure with ventral and dorsal operation is necessary. Solitary metastases of cancer of the prostate, breast, and the thyroid gland show a better prognosis than metastases of cancer of the lung or the stomach. Thus metastases of the first group which also show a dependency on hormones, should be operated on by a ventral procedure, independent of the location of the tumor. In cases of multiple metastases and bad condition of the patient a ventral operation is not indicated. In these cases, a dorsal procedure with decompression and stabilization allows mobility of the patients until only few days before death. An implantation of instrumentations that include a transpedicular screwing can result in spreading of the tumor to the neighboring vertebrae. Therefore, this kind of operation should be the "ultima ratio".
Hopf
C
C
Orthopedic University Clinic Mainz, West Germany.
Heine
J
J
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D006801:Humans; D007738:Kyphosis / Q000209:etiology; D007796:Laminectomy / Q000009:adverse effects; D009984:Orthopedic Fixation Devices; D011379:Prognosis; D013125:Spinal Neoplasms / Q000556:secondary / Q000601:surgery*