The clinical challenge of Lyme disease.
Lyme disease is a systemic infection with protean clinical manifestations. In the past decade the disease has evolved from a medical curiosity to the most common vector-borne disease in the United States. The diverse clinical manifestations together with the lack of standardized serologic tests pose a significant diagnostic challenge for the practicing physician. The epidemiology, clinical presentation, diagnosis, and recommended therapy of Lyme borreliosis are reviewed.
Department of Infectious Disease, Cleveland Clinic Foundation, Ohio 44195-5215.
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Longworth
D000818:Animals; D002985:Clinical Protocols; D006801:Humans; D008193:Lyme Disease / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D051379:Mice; D013752:Tetracycline / Q000627:therapeutic use
D013752:Tetracycline