[The paraneoplastic phenotype of human gastric glands studied using the carcinoembryonic antigen-specific lectin crustacin].
The expression of CEA was studied with the help of rabbit antibody and CEA-specific lectin-krustacin in pepsinogen positive gastric glands near carcinomas and in gastric mucosa with intestinal metaplasia and dysplasia of the epithelium without neoplasia. CEA-krustacin was revealed in 20 out of 41 cases and CEA-antibody in 2 out of 41 cases of gastric glands in mucosa near carcinomas. The results of investigation discover the development in the gastric glands near carcinoma subcellular components. Paraneoplastic phenomenon was found in the majority of the cases.
K K
KK
Pugachev
V V
VV
Kalashnikov
I B
IB
Shimbireva
T A
TA
Belous
D002135:Calcium-Binding Proteins; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D002471:Cell Transformation, Neoplastic / Q000378:metabolism; D002908:Chronic Disease; D004848:Epithelium / Q000378:metabolism; D005753:Gastric Mucosa / Q000378:metabolism*; D005756:Gastritis / Q000378:metabolism; D006651:Histocytochemistry; D006801:Humans; D007124:Immunoenzyme Techniques; D037102:Lectins; D010257:Paraneoplastic Syndromes / Q000378:metabolism*; D010435:Pepsinogens / Q000032:analysis; D010641:Phenotype; D013274:Stomach Neoplasms / Q000378:metabolism
D002135:Calcium-Binding Proteins; D002272:Carcinoembryonic Antigen; D037102:Lectins; D010435:Pepsinogens; C060167:crustacin protein, Pagurus prideauxii
Izuchenie paraneoplasticheskogo fenotipa zhelez zheludka cheloveka s pomoshch'iu rakovo-émbrional'nogo antigens spetsificheskogo lektina krustatsina.