Evaluation of a simple and fast self-test for urine luteinizing hormone.
Ovulation can be predicted by measuring the midcycle urine luteinizing hormone surge with a simple 5-minute enzyme-immunoassay. This assay has proved to be suitable for self-tests with a sensitivity of about 90% and a specificity of 100% in unstimulated and clomiphene citrate stimulated cycles. Whereas a reference method (hemagglutination test) yielded better sensitivity, its specificity was markedly worse. Self-tests carried out by patients and control laboratory tests showed an excellent correlation. Patient compliance with self-tests should not be taken for granted.
Second Department of Gynecology and Obstetrics, University of Vienna, Austria.
C
C
Bieglmayer
F
F
Fischl
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H
Janisch
D000328:Adult; D005069:Evaluation Studies as Topic; D005260:Female; D005544:Forecasting; D006801:Humans; D007124:Immunoenzyme Techniques; D007986:Luteinizing Hormone / Q000652:urine*; D010061:Ovulation Detection / Q000379:methods* / Q000592:standards; D011374:Progesterone / Q000097:blood; D011863:Radioimmunoassay; D012646:Self Administration; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires
D011374:Progesterone; D007986:Luteinizing Hormone