Myoelectric and manometric patterns of human rectosigmoid colon in irritable bowel syndrome and diverticulosis.
Rectosigmoid electric control activity and intraluminal pressure were measured in the fasting state and after a standard 3040-kJ meal in irritable bowel syndrome (IBS) patients (n = 41), diverticulosis patients (n = 15), and healthy controls (n = 13). Analysis of myoelectric and motor patterns was performed computer-based with home-made software. Spectral analysis (fast Fourier transform) and computer recognition of slow waves emulating visual scoring showed very similar slow-wave frequency patterns in all three groups. Calculation of contractile indices displayed a widely scattered variable of motility in all three groups without significant differences. IBS subgroups with different bowel patterns showed very similar frequencies of basic myoelectric rhythm and a considerable overlap of contractile activity without significant differences among the subgroups and compared with controls. Slow-wave rhythm seems unlikely to be the basis of disturbed motility in IBS and diverticular disease. A specific pattern of contractile activity was not detectable in either condition.
Dept. of Internal Medicine, University of Marburg, FRG.
M
M
Katschinski
P
P
Lederer
A
A
Ellermann
R
R
Ganzleben
G
G
Lux
R
R
Arnold
D000328:Adult; D003106:Colon / Q000503:physiopathology*; D003109:Colonic Diseases, Functional / Q000175:diagnosis* / Q000503:physiopathology; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D004241:Diverticulum, Colon / Q000175:diagnosis* / Q000503:physiopathology; D004576:Electromyography; D005260:Female; D005769:Gastrointestinal Motility; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged