[Effect of heparin on erythrocyte damage in various toxicogenic DIC syndromes].
In experiments in vitro it has been established that heparin does not have a direct hemolyzing action, but it significantly reduces red blood cell resistance to acid. In experiments in vivo heparin significantly intensifies red blood cell resistance to the action of acid hemolytics. Hemolysis during intoxication with the toxins studied is, to a greater extent, secondary in relation to the intravascular blood coagulation.
Glazunova
G A
GA
Grigor'ev
G P
GP
Barkagan
Z S
ZS
Koltakova
S I
SI
D000818:Animals; D003470:Culture Media; D004211:Disseminated Intravascular Coagulation / Q000097:blood* / Q000188:drug therapy / Q000209:etiology; D004906:Erythrocyte Count / Q000187:drug effects; D004912:Erythrocytes / Q000187:drug effects / Q000473:pathology*; D005260:Female; D006493:Heparin / Q000494:pharmacology / Q000627:therapeutic use*; D006494:Heparin Antagonists; D066298:In Vitro Techniques; D008297:Male; D011817:Rabbits; D014757:Viper Venoms / Q000009:adverse effects*
D003470:Culture Media; D006494:Heparin Antagonists; D014757:Viper Venoms; D006493:Heparin
Vliianie heparina na povrezhdenie éritrotsitov pri razlichnykh toksikogennykh DVS-sindromakh.