[The effect of tobacco smoke on the activity of proteolytic enzymes and their inhibitors in human oral fluid].
In vitro experiments have shown that unfractionated tobacco smoke in the known concentrations inactivates salivary proteolysis inhibitors, not influencing proteolytic enzymes activities. This phenomenon may be one of the pathogenetic factors contributing to the development of local inflammatory reaction of the oral mucosa in tobacco smokers.
Danilevskiĭ
N F
NF
Ishchenko
L V
LV
D000293:Adolescent; D000328:Adult; D004305:Dose-Response Relationship, Drug; D006801:Humans; D066298:In Vitro Techniques; D010447:Peptide Hydrolases / Q000032:analysis / Q000378:metabolism*; D010947:Plants, Toxic; D011480:Protease Inhibitors / Q000032:analysis / Q000378:metabolism*; D012463:Saliva / Q000032:analysis / Q000187:drug effects* / Q000201:enzymology; D012906:Smoke / Q000009:adverse effects*; D014026:Nicotiana
D011480:Protease Inhibitors; D012906:Smoke; D010447:Peptide Hydrolases
Vliianie tabachnogo dyma na aktivnost' fermentov proteoliza i ikh ingibitorov rotovoĭ zhidkosti cheloveka.