Significance of fill-in after thallium-201 reinjection following delayed imaging: comparison with regional wall motion and angiographic findings.
To identify reversible defects, reinjection of a small amount of thallium-201 (201Tl) following 3-hr delayed imaging was performed in 60 patients with coronary artery disease who had perfusion abnormalities on their post-exercise 201Tl images. Thallium-201 uptake was visually scored and judged as normal (Group 1), reversible defect (Group II), new fill-in after reinjection (Group IIIa) and no fill-in even after reinjection (Group IIIb). New fill-in after reinjection was observed in 27 segments of the 85 segments (32%), showing persistent defect on the stress and delayed images. The wall motion in Group IIIa was worse than Group II but better than Group IIIb. Group IIIa showed Q-wave on ECG more often (69%) than Group II (27%) (p less than 0.01), but less often than Group IIIb (85%) (p less than 0.05). These data indicate that the reinjection 201Tl imaging often identifies new fill-in in the areas of no redistribution on the delayed images and it may hold promise for assessing tissue viability which the conventional imaging may underestimate.
Tamaki
N
N
Department of Radiology and Nuclear Medicine, Kyoto University Faculty of Medicine, Japan.
Ohtani
H
H
Yonekura
Y
Y
Nohara
R
R
Kambara
H
H
Kawai
C
C
Hirata
K
K
Ban
T
T
Konishi
J
J
D000328:Adult; D000368:Aged; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology*; D011877:Radionuclide Imaging; D013794:Thallium Radioisotopes / Q000008:administration & dosage; D013997:Time Factors
D013794:Thallium Radioisotopes