Ossification in nude mice. 1. Macroscopical study.
Ossification was studied in cleared fetuses, newborns, 1- and 6-week-old nu/nu and nu/+ mice of the B 10 LP background. The same ossification pattern was observed in nu/nu and nu/+ in the embryonal period as well as in newborn animals and mice aged 1 or 6 weeks. On the other hand, 6-week-old nu/nu mice exhibited a lower X-ray density of the skeleton and a lower thickness of the proximal tibial growth plate than 6-week-old nu/+ litter mates. The results indicate the influence of postnatal factors on the skeletal development of nu/nu mice.
Department of Anatomy, Faculty of Medicine, Charles University, Prague, Czechoslovakia.
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Smetana
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Holub
D000818:Animals; D001835:Body Weight; D001846:Bone Development; D001842:Bone and Bones / Q000000981:diagnostic imaging; D051379:Mice; D008819:Mice, Nude / Q000033:anatomy & histology / Q000196:embryology / Q000254:growth & development*; D011859:Radiography