Placental-like alkaline phosphatase in seminoma.
Tumor marker identification in testicular cancer has contributed to early detection and monitoring of non-seminomatous disease. A placental alkaline phosphatase-like (PLAP-like) enzyme derived from seminomas has recently been focused upon as a possible marker for this disease. The biochemistry of the PLAP-like enzyme is reviewed, as well as its occurrence in tissue and sera from healthy persons and patients with testicular cancer.
Department of Urology, Kanazawa University, Japan.
K
K
Koshida
B
B
Wahren
D000469:Alkaline Phosphatase / Q000097:blood / Q000378:metabolism*; D014408:Biomarkers, Tumor; D004407:Dysgerminoma / Q000201:enzymology*; D058851:GPI-Linked Proteins; D006801:Humans; D007150:Immunohistochemistry; D007527:Isoenzymes / Q000097:blood / Q000378:metabolism; D008297:Male; D013736:Testicular Neoplasms / Q000201:enzymology*
D014408:Biomarkers, Tumor; D058851:GPI-Linked Proteins; D007527:Isoenzymes; D000469:Alkaline Phosphatase; C019839:alkaline phosphatase, placental