Diagnosis and management of lung allograft rejection.
Improvements in our understanding of the mechanisms underlying the rejection coupled with the development of novel approaches to dealing with the rejection process have allowed successful lung and heart-lung transplantation. Nonetheless, successful lung transplantation is still limited by acute rejection. This article defines the rejection process and outlines current approaches to preventing and treating this major clinical problem.
Baylor College of Medicine, Houston, Texas.
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Lawrence
D006084:Graft Rejection / Q000187:drug effects / Q000276:immunology*; D016041:Heart-Lung Transplantation / Q000276:immunology; D006801:Humans; D008168:Lung / Q000276:immunology; D008171:Lung Diseases / Q000601:surgery; D016040:Lung Transplantation / Q000276:immunology*; D014184:Transplantation, Homologous