The bronchial arteries of the dog after selective embolization of the pulmonary artery with emboli of various size. A morphological study.
The aim of the study was to investigate whether the development of collateral broncho-pulmonary circulation depends on the size of obliterated branches of the pulmonary artery. Massive embolization of the pulmonary arterial bed was performed with sterile plastic spheres of known size from 0.08 to 1.0 mm in diameter in 25 dogs. Three months after embolization, the bronchial arteries were investigated with the use of post mortem bronchial arteriography and histology. The same investigation of the bronchial arteries was performed in 6 control dogs with intact pulmonary circulation. Bronchial arteriography showed conspicuous dilatation of the bronchial arteries in all dogs in which the emboli of 0.4, 0.6 and 1.0 mm in diameter were used for pulmonary artery embolization. Embolization with spheres of 0.08, 0.175 and 0.3 mm in diameter did not cause any enlargement of the bronchial arteries. They were of the same size as those in control dogs. Histological investigation revealed that the bronchial arteries were enlarged and hypertrophic in all dogs which the elastic branches of the pulmonary artery had been occluded. The bronchial arteries never showed an increase in size in case of embolization of muscular arteries or arteriolae. The results showed that the development of collateral bronchopulmonary circulation in the dog depends on the size of the occluded branch of the pulmonary artery.
Rehulová
E
E
Department of Pathological Anatomy, Charles University School of Medicine, Hradec Králové, Czechoslovakia.
Jandík
J
J
Endrys
J
J
D000818:Animals; D001981:Bronchial Arteries / Q000473:pathology*; D003097:Collateral Circulation / Q000502:physiology*; D004285:Dogs; D004547:Elastic Tissue / Q000473:pathology; D009131:Muscle, Smooth, Vascular / Q000473:pathology*; D011655:Pulmonary Embolism / Q000473:pathology*