HMPAO-SPECT imaging resembling Alzheimer-type dementia in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS).
Single-photon emission computed tomography (SPECT) of the brain using hexamethyl propylene amine oxime (HMPAO) was performed in a 37-year-old patient suffering from mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS). Reduced blood flow was observed bilaterally in the parieto-occipital regions (resembling Alzheimer type dementia) and in the right parietal lobe.
Department of Nuclear Medicine University of Bonn, West-Germany.
F
F
Grünwald
S
S
Zierz
K
K
Broich
S
S
Schumacher
A
A
Bockisch
H J
HJ
Biersack
D000140:Acidosis, Lactic / Q000000981:diagnostic imaging*; D000328:Adult; D000544:Alzheimer Disease / Q000000981:diagnostic imaging*; D001927:Brain Diseases / Q000000981:diagnostic imaging*; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008931:Mitochondria, Muscle / Q000000981:diagnostic imaging / Q000473:pathology*; D015609:Organotechnetium Compounds; D010091:Oximes; D013577:Syndrome; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime