Pyruvate kinase deficiency.
PK deficiency is the most common and well characterized erythroenzymopathy in the Embden-Meyerhof glycolytic pathway associated with hereditary hemolytic anemia. History of discovery, clinical features, biochemical studies, as well as recent studies on molecular level were reviewed, with a stress on our own studies. As reference materials, Tables 2 and 3 are attached.
Okinaka Memorial Institute for Medical Research, Tokyo, Japan.
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Miwa
D000743:Anemia, Hemolytic / Q000097:blood / Q000201:enzymology*; D002454:Cell Differentiation; D004912:Erythrocytes / Q000166:cytology / Q000201:enzymology; D006801:Humans; D007527:Isoenzymes / Q000097:blood / Q000172:deficiency*; D011770:Pyruvate Kinase / Q000097:blood / Q000172:deficiency*
D007527:Isoenzymes; D011770:Pyruvate Kinase