Spontaneous remission of nephrotic syndrome in a patient with IgA nephropathy.
A patient with spontaneous remission of nephrotic syndrome (NS) associated with IgA nephropathy is described. The patient presented at the age of 8 years with asymptomatic proteinuria, and at the age of 11 years developed classical features of NS. A percutaneous renal biopsy showed mild mesangial prominence without significant hypercellularity, electron-dense deposits within the mesangium, and 3+ mesangial staining with IgA and IgG. NS resolved 6 weeks after onset without any form of therapy; absence of proteinuria persisted 6 months later. This report demonstrates clearly that patients with NS associated with IgA nephropathy may undergo spontaneous resolution of their proteinuria.
Hogg
R J
RJ
Department of Pediatrics, Baylor University Medical Center, Dallas, TX 75246.
Savino
D A
DA
D001706:Biopsy; D002648:Child; D005920:Glomerular Mesangium / Q000473:pathology; D005922:Glomerulonephritis, IGA / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D009404:Nephrotic Syndrome / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D011507:Proteinuria / Q000209:etiology; D012075:Remission, Spontaneous