Antiatherosclerotic agents. A structurally novel bivalent inhibitor of acylCoA:cholesterol O-acyltransferase with systemic activity.
Gammill
R B
RB
Upjohn Laboratories, Upjohn Company, Kalamazoo, Michigan 49001.
Bell
F P
FP
Bell
L T
LT
Bisaha
S N
SN
Wilson
G J
GJ
D000818:Animals; D001011:Aorta / Q000201:enzymology; D001161:Arteriosclerosis / Q000517:prevention & control*; D002784:Cholesterol / Q000097:blood; D002867:Chromones / Q000138:chemical synthesis / Q000494:pharmacology*; D008099:Liver / Q000201:enzymology; D011817:Rabbits; D051381:Rats; D002785:Sterol O-Acyltransferase / Q000037:antagonists & inhibitors*; D013329:Structure-Activity Relationship
D002867:Chromones; D002784:Cholesterol; D002785:Sterol O-Acyltransferase