[The natural history of coronary disease. The role of cholesterol].
The natural history of the complications of coronary heart disease has been defined by anatomicopathological and epidemiological studies, particularly the Framingham study. At the same time, research is being carried out on risk factors which play a role in the progressive development of atheromatous plaque (atherogenic factors: hypertension: hypercholesterolaemia) and those factors which lead to complications in the atheromatous plaque (aggravating or precipitating factors: smoking, thrombosis, etc.). This schematic perspective may lead to the redefinition of the strategy to adopt in fighting atherosclerotic arterial disease; a better aim will thus the taken in the fight against hypercholesterolaemia.
Service de Cardiologie, Hôpital Louis Pradel, Lyon.
M
M
Ovize
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M
de Lorgeril
G
G
Finet
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Y
Lienhart
J
J
Delaye
D002784:Cholesterol / Q000502:physiology*; D003327:Coronary Disease / Q000453:epidemiology / Q000503:physiopathology*; D006801:Humans; D012307:Risk Factors; D013997:Time Factors
D002784:Cholesterol
Histoire naturelle de la maladie coronaire. La place du cholestérol.