Detection of rabies virus antibodies in fruit bats (Eidolon helvum) from Nigeria.
Fruit bats (Eidolon helvum) were collected from three different localities in Western Nigeria: Oti, Ibadan and Idanre. Fifty serum samples were analyzed using a modified rapid fluorescent focus inhibition technique against rabies, Mokola, Lagos bat and Duvenhage viruses. Twenty-five brain samples were screened for rabies and related lyssavirus antigens by direct fluorescent antibody microscopy and by an indirect fluorescent antibody technique with rabies anti-nucleocapsid monoclonal antibodies. All brain samples were negative. Two serum samples had relatively high anti-rabies activity; no neutralizing activity was detected against Mokola, Lagos bat or Duvenhage viruses.
Wistar Institute of Anatomy and Biology, Philadelphia, Pennsylvania 19104.
H O
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Aghomo
A K
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Ako-Nai
O O
OO
Oduye
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Tomori
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Rupprecht
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D000956:Antigens, Viral / Q000032:analysis; D001921:Brain / Q000382:microbiology; D002685:Chiroptera; D004197:Disease Reservoirs; D005455:Fluorescent Antibody Technique; D009549:Nigeria / Q000453:epidemiology; D011818:Rabies / Q000453:epidemiology / Q000662:veterinary*; D011820:Rabies virus / Q000276:immunology*; D012209:Rhabdoviridae / Q000276:immunology
D000914:Antibodies, Viral; D000956:Antigens, Viral