[Frozen blood from one closely related donor reduced complications of blood transfusion without adverse effects in the open-heart surgery].
We used frozen blood from one closely related donor in 24 patients (group I) who underwent open heart surgery for congenital heart disease, in order to reduce of complications from a large quantity of blood transfusion. Blood of 600-2200 ml was collected from the single donor and was kept frozen until the operation. Two conditions of the patients were instituted, (1) body weight less than or equal to 40 kg (2) the single donor is father or mother or a close relative. The group of these patients was compared with patients using frozen autologous blood (group II) and patients using banked blood (group III). In group I patients two times of decline of red blood cell counts (RBC), hematocrit (Ht), hemoglobin (Hb) and total protein (TP) were noticed. The first was the period during the cardio-pulmonary bypass. The second was the time about one week after the transfusion of frozen red cells. But degree of the decline was uneventful clinically. The increment of complications induced from the use of frozen red cells was not noticed, and there was no case of serum hepatitis in group I patients. We concluded that the open-heart surgery using frozen blood cells (single donor), if the application was appropriate, could be undergone safely and would be effective on reducing infection and reaction induced from blood transfusion.
Department of Cardiovascular Surgery, Cardiovascular Center Sakakibara Hospital, Okayama, Japan.
H
H
Namba
T
T
Hata
Y
Y
Sone
S
S
Takada
M
M
Imamaki
M
M
Kuinose
G
G
Taniguchi
D000293:Adolescent; D000328:Adult; D001782:Blood Donors; D001793:Blood Preservation; D006348:Cardiac Surgical Procedures; D002648:Child; D002675:Child, Preschool; D015925:Cryopreservation; D005190:Family; D005260:Female; D005615:Freezing; D006330:Heart Defects, Congenital / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D065227:Transfusion Reaction