Spontaneous remission of nephrotic syndrome in a patient with IgA nephropathy.
A patient with spontaneous remission of nephrotic syndrome (NS) associated with IgA nephropathy is described. The patient presented at the age of 8 years with asymptomatic proteinuria, and at the age of 11 years developed classical features of NS. A percutaneous renal biopsy showed mild mesangial prominence without significant hypercellularity, electron-dense deposits within the mesangium, and 3+ mesangial staining with IgA and IgG. NS resolved 6 weeks after onset without any form of therapy; absence of proteinuria persisted 6 months later. This report demonstrates clearly that patients with NS associated with IgA nephropathy may undergo spontaneous resolution of their proteinuria.
Department of Pediatrics, Baylor University Medical Center, Dallas, TX 75246.
R J
RJ
Hogg
D A
DA
Savino
D001706:Biopsy; D002648:Child; D005920:Glomerular Mesangium / Q000473:pathology; D005922:Glomerulonephritis, IGA / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D009404:Nephrotic Syndrome / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D011507:Proteinuria / Q000209:etiology; D012075:Remission, Spontaneous