[4-way immunosuppression in pre-sensitized recipients of allogenic cadaver kidney transplants].
As a result of introduction of quadruple immunosuppression using cyclosporine, antithymocyte globulin, azathioprine and prednisone in immunological high-risk patients with a presensitization greater than or equal to 80% and/or multiple grafts the rate of immediate graft function could significantly increased, the frequency of rejection and graft rupture was reduced and the patient survival rate could improved to 100%. The problem of vascular rejection should resolved by a more aggressive biopsy approach.
Urologische Klinik, des Krankenhauses im Friedrichshain.
H
H
Oesterwitz
G
G
May
P
P
Müller
V
V
Strobelt
W
W
Seeger
F
F
Seibt
R
R
Horlbeck
C
C
Hansen
D000961:Antilymphocyte Serum / Q000008:administration & dosage; D001379:Azathioprine / Q000008:administration & dosage; D002102:Cadaver; D003524:Cyclosporins / Q000008:administration & dosage; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006084:Graft Rejection / Q000187:drug effects*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D007676:Kidney Failure, Chronic / Q000601:surgery*; D007677:Kidney Function Tests; D016030:Kidney Transplantation / Q000276:immunology*; D008775:Methylprednisolone / Q000008:administration & dosage; D012083:Renin / Q000097:blood; D012086:Reoperation
D000961:Antilymphocyte Serum; D003524:Cyclosporins; D007166:Immunosuppressive Agents; D012083:Renin; D001379:Azathioprine; D008775:Methylprednisolone
Vierfach-Immunsuppression bei präsensibilisierten Rezipienten allogener Leichennierentransplantate.