The usefulness of faecal haemoglobin, albumin and alpha-1-antitrypsin in the detection of gastrointestinal bleeding.
A pilot study was undertaken to find out whether faecal haemoglobin, albumin and alpha-1-antitrypsin from patients with gastrointestinal disorders could distinguish active bleeders from non-active bleeders and healthy volunteers. Alpha-1-antitrypsin is not as readily degraded by endogenous and bacterial breakdown as haemoglobin and albumin and consequently could be a better marker for occult bleeding.
Department of Clinical Chemistry, East Birmingham Hospital, Bordesley Green East, UK.
R J
RJ
Morrow
N
N
Lawson
S H
SH
Hussaini
P
P
Asquith
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000418:Albumins / Q000032:analysis*; D015415:Biomarkers / Q000032:analysis; D005243:Feces / Q000032:analysis*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis*; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D012680:Sensitivity and Specificity; D000515:alpha 1-Antitrypsin / Q000032:analysis*
D000418:Albumins; D015415:Biomarkers; D006454:Hemoglobins; D000515:alpha 1-Antitrypsin