Antibiotic susceptibility of Escherichia coli isolates from inpatients with urinary tract infections in hospitals in Addis Ababa and Stockholm.
A high level of antimicrobial resistance of bacteria has been detected at the Tikur Anbessa Hospital (TAH), Addis Ababa, for many years. In contrast, at the Karolinska Hospital (KH), Stockholm, the level of resistance is low. Reported are the results of an investigation of the correlation between antibiotic usage and the antimicrobial resistance rates of Escherichia coli isolates from patients with urinary tract infections in these hospitals. At TAH the strains of E. coli isolated were considerably more resistant to all seven antibiotics tested. The level of multiresistance was 63% at TAH and 7% at KH. There were no significant differences in the total amount of antibiotics used in the two hospitals, except for antituberculosis agents. The strain biotypes and antibiograms, together with the length of patients' hospitalization before a positive urine culture was obtained, suggest that the majority of the strains from TAH were of nosocomial origin.
Department of Clinical Microbiology, Karolinska Institute, Stockholm, Sweden.
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S
Ringertz
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Bellete
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Karlsson
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Ohman
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M
Gedebou
G
G
Kronvall
D003428:Cross Infection / Q000188:drug therapy* / Q000382:microbiology / Q000652:urine; D004352:Drug Resistance, Microbial; D004927:Escherichia coli Infections / Q000188:drug therapy* / Q000382:microbiology / Q000652:urine; D005002:Ethiopia; D006786:Hospitals, Urban; D006801:Humans; D013548:Sweden; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology / Q000652:urine