[Modulation of pancreatic chymotrypsin messenger RNA during post-natal development and weaning in calves].
Levels of chymotrypsin mRNA in the pancreatic tissue of preruminant calves were significantly decreased on d 28 and to a lesser extent on d 119 as compared to those of newborns. Enzymic activity regularly increased during the same period. By contrast, both chymotrypsin-specific activity and the mRNA level in the ruminant animals were enhanced on d 119 (1.4- and 2.3-fold, respectively), suggesting that some pretranslational regulation of the chymotrypsin gene was induced by weaning.
Laboratoire du Jeune Ruminant, INRA, Rennes, France.
I
I
Le Huerou
C
C
Wicker
P
P
Guilloteau
R
R
Toullec
A
A
Puigserver
D000818:Animals; D002417:Cattle / Q000235:genetics / Q000254:growth & development*; D002918:Chymotrypsin / Q000096:biosynthesis / Q000235:genetics*; D015971:Gene Expression Regulation, Enzymologic; D008297:Male; D010179:Pancreas / Q000201:enzymology*; D012333:RNA, Messenger / Q000378:metabolism*; D014886:Weaning
D012333:RNA, Messenger; D002918:Chymotrypsin
Modulation de l'ARN messager de la chymotrypsine pancréatique au cours du développement post-natal et du sevrage chez le veau.