[Preservative-free timolol eye drops--surface-anesthetic effect and local compatibility].
0.5% timolol without preservative reduces corneal sensitivity for a shorter period of time than timolol with preservative. The subjective tolerance of unpreserved timolol is much better than that of preserved timolol. The latter and 0.5% levobunolol are significantly more poorly tolerated than buffer solution. The smaller the anesthetic side effects, the better the subjective tolerance of the beta-blockers.
Augenklinik der Universität des Saarlandes, Homburg/Saar, FRG.
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D000293:Adolescent; D000328:Adult; D000779:Anesthetics, Local / Q000009:adverse effects; D003315:Cornea / Q000187:drug effects*; D006801:Humans; D002040:Levobunolol / Q000494:pharmacology; D008875:Middle Aged; D010592:Pharmaceutic Aids / Q000494:pharmacology*; D011310:Preservatives, Pharmaceutical / Q000009:adverse effects / Q000494:pharmacology*; D013999:Timolol / Q000009:adverse effects / Q000494:pharmacology*
D000779:Anesthetics, Local; D010592:Pharmaceutic Aids; D011310:Preservatives, Pharmaceutical; D013999:Timolol; D002040:Levobunolol
Nicht konservierte Timolol-Augentropfen--Lokalanästhetische Wirkung und subjektive Verträglichkeit.