[Pro-oxidant-induced proteolysis in the postradiation interphase death of thymocytes].
Activity of intracellular alkaline proteinases increased and that of the trypsin-like proteinase inhibitors decreased in thymocytes at early times following whole-body X-irradiation of rats with a dose of 4 Gy. Pro-oxidant mechanisms of intracellular proteolysis activation are discussed.
Kozhemiakin
L A
LA
Kraevoĭ
S A
SA
D000818:Animals; D002470:Cell Survival / Q000502:physiology / Q000528:radiation effects; D002843:Chromatin / Q000201:enzymology / Q000528:radiation effects; D005609:Free Radicals; D007399:Interphase / Q000502:physiology / Q000528:radiation effects*; D015227:Lipid Peroxidation / Q000528:radiation effects; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism / Q000528:radiation effects; D010447:Peptide Hydrolases / Q000378:metabolism / Q000528:radiation effects*; D051381:Rats; D013950:Thymus Gland / Q000201:enzymology / Q000528:radiation effects*; D013997:Time Factors; D014361:Trypsin Inhibitors / Q000378:metabolism / Q000528:radiation effects; D014916:Whole-Body Irradiation
D002843:Chromatin; D005609:Free Radicals; D014361:Trypsin Inhibitors; D008315:Malondialdehyde; D010447:Peptide Hydrolases
Prooksidantno-indutsirovannyĭ proteoliz v postluchevoĭ interfaznoĭ gibeli timotsitov.