Liposome immunoassay for rapid identification of group A streptococci directly from throat swabs.
The Q Test Strep (Becton Dickinson and Co., Franklin Lakes, N.J.) is a new solid-phase liposome immunoassay for the rapid diagnosis of group A beta-hemolytic streptococcal pharyngitis. Compared with blood agar plate cultures, the Q Test Strep had a sensitivity of 91%, a specificity of 83%, a positive predictive value of 88%, and a negative predictive value of 87%. Liposome technology can be used to facilitate the rapid diagnosis of group A beta-hemolytic streptococcal pharyngitis.
Department of Pediatrics, University of Connecticut Health Center, Farmington 06032.
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Gerber
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Randolph
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DeMeo
D006801:Humans; D007118:Immunoassay; D008081:Liposomes; D010612:Pharyngitis / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology; D012680:Sensitivity and Specificity; D013290:Streptococcal Infections / Q000150:complications / Q000175:diagnosis*; D013297:Streptococcus pyogenes / Q000302:isolation & purification*
D008081:Liposomes