[Use of beta 1-adrenostimulants in circulatory failure in patients with chronic inflammatory lung diseases].
In 34 patients with chronic cor pulmonale, the drugs from a group of beta-adrenostimulants, nonachlazinum and oxyphedrinum, were tested for effects on their hemodynamics, pulmonary ventilation function, blood gas composition and acid-base balance. In patients with circulatory failure due to lung diseases, nonachlazinum and oxyphedrinum were found to exert a pronounced positive intropic action, to contribute to an increase in cardiac output. The agents may be included into the multimodality therapy of patients with decompensated chronic cor pulmonale.
V K
VK
Gavrisiuk
N D
ND
Morskaia
A I
AI
Iachnik
N A
NA
Morozova
T V
TV
Iakhnitsia
D000293:Adolescent; D000328:Adult; D000368:Aged; D001991:Bronchitis / Q000150:complications*; D002908:Chronic Disease; D002986:Clinical Trials as Topic; D005260:Female; D006333:Heart Failure / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009628:Nonachlazine / Q000627:therapeutic use*; D010099:Oxyfedrine / Q000627:therapeutic use*; D010640:Phenothiazines / Q000627:therapeutic use*; D011427:Propiophenones / Q000627:therapeutic use*; D012119:Respiration / Q000187:drug effects / Q000502:physiology; D014397:Tuberculosis, Pulmonary / Q000150:complications*
D010640:Phenothiazines; D011427:Propiophenones; D009628:Nonachlazine; D010099:Oxyfedrine
Primenenie beta 1-adrenostimuliatorov pri nedostatochnosti krovoobrashcheniia u bol'nykh s khronicheskimi vospalitel'nymi zabolevaniiami legkikh.