What's new in the causes of hemorrhage in acute myelogenous leukemia?
Hemorrhages in AML are still a major problem, although not the most important and different factors are involved in its genesis. The causes that predispose an AML patient to bleed will be reviewed, the hypotheses concerning the coagulation disorder specially found in the FAB M3 type will be discussed and the increasingly recognized role of plasminogen activators and enzymes released from blasts will be emphasized.
Rössle
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Dept. of Internal Medicine, University of Münster, FRG.
Ostermann
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D006470:Hemorrhage / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D015479:Leukemia, Myelomonocytic, Acute / Q000150:complications* / Q000473:pathology / Q000503:physiopathology