[Insufficient formation of interferon in children with recurrent respiratory infections].
The authors investigated the ability of IFN-alpha formation in 50 children followed up on account of frequent and relapsing respiratory diseases. The ability to produce IFN-alpha was consistent with the clinical condition. Children who were frequently ill and whose condition did not improve during the last two years had an inadequate IFN-alpha production. Conversely, children whose health status improved substantially during the follow up period or those who were considered cured had a normal IFN-alpha production. Influencing of the IFN-alpha production might have a favourable effect on the clinical course of the disease.
Vanĕcek
K
K
Ustav výzkumu vývoje ditĕte 2. lékarské fakulty Univerzity Karlovy, Praha.
Lehovcová
A
A
Hlousková
Z
Z
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007370:Interferon Type I / Q000096:biosynthesis*; D008297:Male; D012008:Recurrence; D012141:Respiratory Tract Infections / Q000276:immunology*
D007370:Interferon Type I
Nedostatecná tvorba interferonu u dĕtí s opakovanými respiracními infekcemi.