How toxic is 2,3,7,8-tetrachlorodibenzodioxin to humans?
The tissue levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) measured in different species are reviewed. Based on the correlation of tissue levels and a toxic response in different species, humans are less or no more susceptible to the toxic effects of TCDD than most of the laboratory animals that have been studied. Thus, the present exposure of the general population to environmental levels of TCDD are related compounds should not be of concern.
Kimbrough
R D
RD
Office of the Administrator, U.S. Environmental Protection Agency, Washington, D.C. 20460.
D000818:Animals; D001822:Body Burden; D004147:Dioxins / Q000633:toxicity*; D004781:Environmental Exposure; D006801:Humans; D000072317:Polychlorinated Dibenzodioxins / Q000493:pharmacokinetics / Q000633:toxicity*; D013045:Species Specificity; D014018:Tissue Distribution
D004147:Dioxins; D000072317:Polychlorinated Dibenzodioxins