Thyroid cancer causing death after 40 years: rationale for initial intensive treatment.
Three cases of death after 40 years of differentiated thyroid cancer are presented. Prolonged follow-up identified relapses in patients assumed to have been cured. Thus the case is argued for intensive initial therapy comprising near-total thyroidectomy (including excision of any macroscopic nodal disease) and ablative iodine-131 therapy in addition to thyroid hormone suppression.
Thyroid Unit, Royal Marsden Hospital, London.
S
S
Powell
C
C
Harmer
D000230:Adenocarcinoma / Q000556:secondary / Q000628:therapy*; D000328:Adult; D002291:Carcinoma, Papillary / Q000556:secondary / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008136:Longevity; D008297:Male; D012008:Recurrence; D013964:Thyroid Neoplasms / Q000628:therapy*; D013965:Thyroidectomy
D007457:Iodine Radioisotopes