Visceral pain: a review of experimental studies.
This paper reviews clinical and basic science research reports and is directed toward an understanding of visceral pain, with emphasis on studies related to spinal processing. Four main types of visceral stimuli have been employed in experimental studies of visceral nociception: (1) electrical, (2) mechanical, (3) ischemic, and (4) chemical. Studies of visceral pain are discussed in relation to the use and 'adequacy' of these stimuli and the responses produced (e.g., behavioral, pseudoaffective, neuronal, etc.). We propose a definition of an adequate noxious visceral stimulus and speculate on spinal mechanisms of visceral pain.
Department of Anesthesia, College of Medicine, University of Iowa, Iowa City, IA 52242, U.S.A. Department of Pharmacology, College of Medicine, University of Iowa, Iowa City, IA 52242, U.S.A.
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TJ
Ness
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Gebhart
D015746:Abdominal Pain / Q000209:etiology / Q000503:physiopathology; D000818:Animals; D002415:Cats; D002637:Chest Pain / Q000209:etiology / Q000503:physiopathology; D004558:Electric Stimulation; D006801:Humans; D009475:Neurons, Afferent / Q000502:physiology*; D010812:Physical Stimulation; D011323:Primates; D014781:Viscera / Q000294:innervation* / Q000503:physiopathology