Primary intracerebral plasma cell granuloma: a light, immunocytochemical, and ultrastructural study of one case.
A case of primary intracerebral plasma cell granuloma without meningeal attachment is presented. Histologically, the lesion showed two different patterns. At the center, it displayed the features of a benign fibrous histiocytoma. At the periphery, a mixture of polyclonal plasma cells, lymphocytes, and "epithelial-like" cells was observed. Electron microscopy and immunocytochemistry confirmed the histiocytic nature of the "epithelial-like cells." The differential diagnosis and histogenesis of such a lesion are discussed.
Department of Neuropathology, Centre Hospitalier Regional, Marseille, France.
D
D
Figarella-Branger
D
D
Gambarelli
M
M
Perez-Castillo
L
L
Garbe
F
F
Grisoli
D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D005904:Glial Fibrillary Acidic Protein / Q000378:metabolism*; D006099:Granuloma / Q000473:pathology*; D006104:Granuloma, Plasma Cell / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D011859:Radiography; D014746:Vimentin / Q000378:metabolism*
D005904:Glial Fibrillary Acidic Protein; D014746:Vimentin