The role of colony-stimulating factors in acute leukemia.
This article summarises the effects of colony-stimulating factors and related molecules on leukemia blasts by focussing on autocrine and paracrine growth control. This information may lead to a better understanding of the pathobiology of this highly malignant disorder, and may have therapeutic implications.
Department of Hematology and Oncology, University of Freiburg, Federal Republic of Germany.
F
F
Herrmann
E
E
Vellenga
D003115:Colony-Stimulating Factors / Q000502:physiology*; D011905:Genes, ras; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000473:pathology*
D003115:Colony-Stimulating Factors