[Trophic effect of testosterone on erythropoiesis in the mouse].
Some differences between erythropoietin biogenesis under the action of natural stimuli and that resulting from testosterone administration are commented. Evidences are presented suggesting that androgens, apart from amplifying erythropoietin production, might exert some action on the stroma as specific erythrocytic tissue. This action could be anabolic or trophic and not erythropoietin dependent, at least to some extent, its effect being applied on the quantitative erythropoietic homeostasis.
Departamento ERITAL (CONICET), Universidad Nacional de Jujuy, Argentina.
J L
JL
Scaro
C
C
Miranda
M A
MA
Carrera
B
B
Martín
I
I
Torrejón
M C
MC
Buys
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects; D002248:Carbon Monoxide / Q000494:pharmacology; D004920:Erythropoiesis / Q000187:drug effects* / Q000528:radiation effects; D004921:Erythropoietin / Q000097:blood; D005260:Female; D000860:Hypoxia / Q000097:blood; D051379:Mice; D008809:Mice, Inbred C3H; D013268:Stimulation, Chemical; D013739:Testosterone / Q000494:pharmacology*; D014916:Whole-Body Irradiation
D004921:Erythropoietin; D013739:Testosterone; D002248:Carbon Monoxide
Acción trófica de la testosterona sobre la eritropoyesis del ratón.