[New methods of interlaboratory monitoring of HIV-1 ELISA kits. Comparative study of 2 periods: 1/12/1988 to 15/4/1989 and 15/4/1989 to 31/8/1989. Le Groupe Rétrovirus de la Sociètè Nationale de Transfusion Sanguine].
Since december 1st 1988, the Retrovirus study Group of the French Society of Blood Transfusion has initiated a systematic multicentric control of all anti-HIV screening EIA test kits lots used by each member of the group. For this purpose a special panel (GRV) has been designed and forwarded to each laboratory. From december 1st 1988 to august 8 1989, 6 HIV-1 kits have been in use (Diagnostics Pasteur Elavia 1; Diagnostics Pasteur Rapid'Elavia; Organon Vironostika; Abbott HIV recombinant; Du Pont env 9; Wellcome Wellcozyme). The GRV panel has been run 204 times on 102 different lots in 12 laboratories. Results after 9 months show that these 6 kits almost always properly recognize the 5 HIV 1 positive samples of the panel. However they differ in their ability to recognize HIV 2 positive samples. Variations in results are observed from lot to lot as well as between the first half of this period and the second.
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D015492:AIDS Serodiagnosis / Q000379:methods* / Q000592:standards; D004797:Enzyme-Linked Immunosorbent Assay; D005602:France; D015483:HIV Antibodies / Q000032:analysis*; D015488:HIV Antigens / Q000276:immunology; D006679:HIV Seropositivity / Q000175:diagnosis*; D015497:HIV-1 / Q000276:immunology*; D015498:HIV-2 / Q000276:immunology*; D006801:Humans; D011237:Predictive Value of Tests; D011933:Reagent Kits, Diagnostic; D011994:Recombinant Proteins / Q000276:immunology
D015483:HIV Antibodies; D015488:HIV Antigens; D011933:Reagent Kits, Diagnostic; D011994:Recombinant Proteins
Neuf mois de contrôle interlaboratoire des trousses Elisa VIH 1. Etude comparative de deux périodes: 1/12/1988 au 15/4/1989 et 15/4/1989 au 31/8/1989. Le Groupe Rétrovirus de la Société Nationale de Transfusion Sanguine.