Efficacy of ceftizoxime in the treatment of uncomplicated gonorrhoea: comparison with amoxycillin.
Four centres contributed a total of 466 patients to a study comparing the efficacy of oral amoxycillin with that of probenecid and intramuscular ceftizoxime. Both treatments were equally efficacious, except in the small number of penicillinase-producing Neisseria gonorrhoeae patients, all of whom responded to ceftizoxime and none to amoxycyllin. Both treatments were well tolerated, the only two adverse effects occurring in the ceftizoxime group.
Veeravahu
M
M
Warrington District Hospital, Cheshire.
Clay
J C
JC
Mohanty
K C
KC
Tovey
S J
SJ
Wanas
T M
TM
Roberts
K N
KN
D000293:Adolescent; D000328:Adult; D000658:Amoxicillin / Q000627:therapeutic use*; D015296:Ceftizoxime / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011339:Probenecid / Q000627:therapeutic use
D000658:Amoxicillin; D015296:Ceftizoxime; D011339:Probenecid