The use of laboratory animals in toxicology: an ophthalmoscopic assessment.
In a recent text by Grant (3), approximately 2,800 substances are listed as having some type of untoward effect on ocular tissue. The kinds of substances that may cause toxic damage/effects range from carbolic acid (2) to oxygen (1). It is the purpose of this communication to briefly review ocular toxicology as investigated in laboratory animals.
Toxicology/Pathology Department, Ciba-Geigy Corporation, Summit, New Jersey 07901.
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D000818:Animals; D002415:Cats; D004195:Disease Models, Animal; D004285:Dogs; D005123:Eye / Q000187:drug effects* / Q000473:pathology / Q000503:physiopathology; D005128:Eye Diseases / Q000139:chemically induced*; D051379:Mice; D011323:Primates; D051381:Rats; D012756:Sheep; D014118:Toxins, Biological / Q000633:toxicity*
D014118:Toxins, Biological