Animal models for AIDS.
Animal models will play a central role in AIDS research in the coming years. Important models for human immunodeficiency virus (HIV)-induced disease in humans include HIV-infected great apes, simian immunodeficiency virus-infected Asian monkeys and infections of ungulates and cats with HIV-related lentiviruses. The nature of the diseases induced by these viruses are described here by Norman Letvin, emphasizing aspects with particular relevance to human HIV infections.
Letvin
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Harvard Medical School, New England Regional Primate Research Center, Southborough, MA 01772.
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology*; D000818:Animals; D004195:Disease Models, Animal; D015658:HIV Infections / Q000276:immunology; D016180:Lentivirus Infections / Q000276:immunology; D016097:Simian Acquired Immunodeficiency Syndrome / Q000276:immunology; D015302:Simian Immunodeficiency Virus / Q000276:immunology