Donor insemination--a look to the future.
In this article we have reviewed many aspects of donor insemination. The deficiencies in the screening of semen donors especially for sexually-transmitted diseases has been discussed and importance of a rational protocol for recruitment and screening of potential donors has been emphasized. Factors influencing the success and outcome of donor insemination have been reviewed with particular emphasis on providing prognostic guidelines to potential donor insemination couples as to the success and outcome of the treatment. The importance of accurate timing of inseminations in determining the success of donor insemination has also been discussed. However, as has been highlighted throughout this review, there is a lack of specific prospective controlled trials, which are clearly necessary to answer specific important questions. Also emphasized has been the need of these trials to answer such basic questions as the influence of accurate timing on conception rates in specific groups of insemination recipients.
Harris Birthright Research Centre for Reproductive Medicine, Jessop Hospital for Women, Sheffield, United Kingdom.
C L
CL
Barratt
M
M
Chauhan
I D
ID
Cooke
D005260:Female; D005307:Fertilization in Vitro / Q000379:methods; D006801:Humans; D007315:Insemination, Artificial / Q000379:methods* / Q000639:trends*; D007316:Insemination, Artificial, Heterologous / Q000379:methods*; D008297:Male; D013074:Sperm Banks / Q000639:trends