Application of molecular cytogenetic techniques to the evaluation of renal parenchymal tumors.
This guest editorial discusses the molecular cytogenetic features of human renal parenchymal tumors with an emphasis on their diagnostic usefulness. Important contributions of this review are discrimination (a) between papillary and nonpapillary renal cell carcinomas and (b) between tubulopapillary adenomas and papillary carcinomas. Speculations regarding the histogenesis of different renal parenchymal tumors are presented, with the hope that they may serve to diminish some of the confusion surrounding the classification of these tumors.
Biological Carcinogenesis and Development Program, Program Resources Inc., National Cancer Institute, Frederick Cancer Research Facility, MD 21701.
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D000236:Adenoma / Q000235:genetics / Q000473:pathology; D000483:Alleles; D002291:Carcinoma, Papillary / Q000235:genetics* / Q000473:pathology; D002292:Carcinoma, Renal Cell / Q000235:genetics* / Q000473:pathology; D002869:Chromosome Aberrations / Q000235:genetics*; D002872:Chromosome Deletion; D002874:Chromosome Mapping; D002883:Chromosomes, Human, Pair 14; D002886:Chromosomes, Human, Pair 17; D002893:Chromosomes, Human, Pair 3; D002897:Chromosomes, Human, Pair 7; D003937:Diagnosis, Differential; D066246:ErbB Receptors / Q000235:genetics; D005190:Family; D005192:Family Health; D006801:Humans; D007680:Kidney Neoplasms / Q000235:genetics* / Q000473:pathology
D066246:ErbB Receptors