Overview of the virulence attributes of the HAP-group of bacteria.
The pathogenicity requirements of the HAP bacteria include colonization of mucous surfaces, invasion of the host tissues, survival and multiplication in the host, interference with the defences of the host, and damage to the host. For these purposes the bacteria possess adhesion structures, capsular polysaccharides, surface structures such as outer membrane proteins, and lipopolysaccharides. They also secrete extracellular products, including exotoxins. The information available in this context for the major pathogens of the HAP group is reviewed.
Nicolet
J
J
Institute of Veterinary Bacteriology, University of Berne, Switzerland.
D000189:Actinobacillus Infections / Q000382:microbiology*; D000818:Animals; D001422:Bacterial Adhesion; D001427:Bacterial Toxins / Q000502:physiology; D006192:Haemophilus Infections / Q000382:microbiology*; D006801:Humans; D008070:Lipopolysaccharides / Q000502:physiology; D010326:Pasteurella Infections / Q000382:microbiology*; D015661:Pasteurellaceae / Q000472:pathogenicity*; D011135:Polysaccharides, Bacterial / Q000502:physiology; D014774:Virulence
D001427:Bacterial Toxins; D008070:Lipopolysaccharides; D011135:Polysaccharides, Bacterial