[Structural changes in the DNA of the blood nucleotides and the development of late sequelae in irradiated rats].
Fluorescent analysis of structural changes of nucleotide in the blood associated with AT fragments has been studied in rats, gamma-irradiated with doses of 2 and 4 Gy. It was demonstrated that the haematological, gerontological and cancerogenic late consequences were preceded by the structural genomic disturbances determined by 30 day after irradiation.
Ivanov
S D
SD
Remizova
I V
IV
Kovan'ko
E G
EG
Gubareva
A V
AV
Komar
V E
VE
D000818:Animals; D004247:DNA / Q000097:blood / Q000235:genetics / Q000528:radiation effects*; D004996:Ethidium; D005456:Fluorescent Dyes; D005720:Gamma Rays; D007211:Indoles; D007962:Leukocytes / Q000528:radiation effects; D008297:Male; D009711:Nucleotides / Q000097:blood / Q000235:genetics / Q000528:radiation effects*; D011833:Radiation Injuries, Experimental / Q000097:blood* / Q000209:etiology / Q000235:genetics / Q000401:mortality / Q000473:pathology; D051381:Rats; D013997:Time Factors; D014916:Whole-Body Irradiation
D005456:Fluorescent Dyes; D007211:Indoles; D009711:Nucleotides; C007293:DAPI; D004247:DNA; D004996:Ethidium
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