[Immobilization of antibiotics on a titanium surface].
Immobilization of antibiotics on the surface of electrolytically oxidated titanium was tried. Transfer of the immobilized ampicillin into hardly soluble calcium ampicillate resulted in providing the coating with antimicrobial activity for 5 days. The quantity of the immobilized antibiotic determined polarographically amounted to 6.4.10(-3) mol per 1 m2 of the surface.
Tikhonova
L S
LS
Samedov
T I
TI
Galkin
V Iu
VIu
Babkov
V V
VV
Makarov
K A
KA
Efimov
A G
AG
D000327:Adsorption; D000667:Ampicillin / Q000008:administration & dosage / Q000493:pharmacokinetics*; D004343:Drug Implants; D004355:Drug Stability; D004866:Equipment Contamination / Q000517:prevention & control*; D004926:Escherichia coli / Q000187:drug effects*; D066298:In Vitro Techniques; D008034:Lincomycin / Q000008:administration & dosage / Q000493:pharmacokinetics*; D019736:Prostheses and Implants; D013211:Staphylococcus aureus / Q000187:drug effects*; D013499:Surface Properties; D013997:Time Factors; D014025:Titanium
D004343:Drug Implants; C009495:titanium dioxide; D000667:Ampicillin; D008034:Lincomycin; D014025:Titanium
Immobilizatsiia antibiotikov na poverkhnosti titana.