[The significance of the cellular factor in realizing the restorative effect of the procedure of bone marrow exfusion, incubation and reimplantation in irradiated mice].
In experiments with F1 (CBA X C57Bl) mice irradiated with doses of 6.5 to 8.5 Gy the evidence was obtained for the important role of the reimplanted cells in a complete realization of the reparative effect of exfusion, incubation and reimplantation of bone marrow. The increase in radiation dose was accompanied by a tendency towards the decrease in the efficacy of the procedure, and, perhaps, by changes in the ratio of roots of haemopoietic stem cell differentiation.
A N
AN
Zernichenko
V N
VN
Limarenko
L M
LM
Rozhdestvenskiĭ
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects / Q000528:radiation effects*; D001854:Bone Marrow Cells; D016026:Bone Marrow Transplantation / Q000379:methods*; D003114:Colony-Forming Units Assay; D004307:Dose-Response Relationship, Radiation; D005069:Evaluation Studies as Topic; D005720:Gamma Rays; D006410:Hematopoiesis / Q000528:radiation effects; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D011833:Radiation Injuries, Experimental / Q000628:therapy*; D014916:Whole-Body Irradiation
Znachimost' kletochnogo faktora v realizatsii vosstanavlivaiushchego éffekta protsedury éksfuzii, inkubatsii i reimplantatsii kostnogo mozga u obluchennykh mysheĭ.