[Bronchial hyperreactivity or broncho obstructive hyper response].
In this article bronchial hyperreactivity (BHR) is defined and a series of factors which may be involved are discussed: genetic, neurovegetative imbalance, increase in the bronchial epithelial permeability, inflammation and mechanical factors which cause the shortening of the bronchial smooth muscle. A less rigid bronchial cartilage and a decrease in pulmonary elasticity, as well as a thickening of the bronchial wall due to a relative hypertrophy of the glandular tissue might just explain the occurrence of bronchial hyperreactivity in breast-feeding newborns, which actively wheeze and later outgrow the abnormality, and those cases of persistent BHR who repeatedly wheeze. This hyperbronchial response reappears with the aging of the lung tissue.
Depto de Pediatría, Hospital Exequiel González Cortés, Facultad de Medicina, Universidad de Chile, Santiago de Chile.
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Girardi-Briere
D000293:Adolescent; D001249:Asthma / Q000209:etiology / Q000503:physiopathology; D001980:Bronchi / Q000503:physiopathology*; D001985:Bronchial Provocation Tests; D002648:Child; D006801:Humans
Hiperreactividad bronquial o hiper respuesta bronco obstructiva.