[What is the best treatment in massive pulmonary embolism: anticoagulants, thrombolytics or surgical embolectomy?].
The aim of this work was to identify the best treatment available for massive pulmonary thromboembolism which still remains a frequent and sometimes lethal complication for surgical and non-surgical patients. The Authors underline the difficulties of diagnosis and the need for therapy at the earliest possible stage. At present, clinical management involves the use of: anticoagulants, thrombolytic agents and surgical embolectomy. In conclusion, the authors state that pulmonary thromboembolism, even when massive, has been transformed into a medically interesting pathology which can be cured using heparin and thrombolytic agents. However, surgical treatment is mandatory when patients reveal adverse effects to drug therapy, when medical therapy is insuccessful, or when patients are seriously ill with recurrent cardiac arrest.
Istituto di Clinica Cardiovascolare, Università degli Studi, G. D'Annunizo Chieti.
F
F
Glieca
P
P
Santarelli
N
N
Luciani
G
G
La Rovere
G
G
Battaglini
L
L
Stoduto
A
A
Antico
A
A
Bellisario
G
G
Colamussi
A M
AM
Calafiore
D000925:Anticoagulants / Q000627:therapeutic use*; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D011655:Pulmonary Embolism / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*
D000925:Anticoagulants; D005343:Fibrinolytic Agents; D006493:Heparin
Quale trattamento per l'embolia polmonare massiva: gli anticoagulanti, i trombolitici o l'embolectomia chirurgica?