Corneal changes in Tay-Sachs disease.
Tay-Sachs disease is a well-known inherited disease leading to an accumulation of gangliosides in the brain and retina. Our report is based on a case of Tay-Sachs disease in a non-Jewish infant where pathologic changes were noted in corneal endothelium as well as in the retina.
Department of Ophthalmology, University of Toronto, Ont.
M
M
Ghosh
W S
WS
Hunter
C
C
Wedge
D003316:Corneal Diseases / Q000209:etiology / Q000235:genetics / Q000473:pathology*; D004728:Endothelium, Corneal / Q000648:ultrastructure*; D005260:Female; D006580:Genetic Carrier Screening; D006801:Humans; D007223:Infant; D008854:Microscopy, Electron; D012160:Retina / Q000648:ultrastructure; D013661:Tay-Sachs Disease / Q000150:complications / Q000235:genetics / Q000473:pathology*