[Titration and stability tests for antimeasles vaccine].
Production and quality of the vaccines, are important activities in the prevention of measles disease. Edmonston-Zagreb measles vaccine is the main strain attenuated virus distributed in México. In order to evaluate the titer of Edmonston-Zagreb and Schwarz vaccines, 50% tissue culture infective dose (TCID50/0.5 mL) and plaque-forming units (PFU) are performed in the National Laboratory of Public Health. Furthermore PFU is a method used in the stability vaccine test. Validation criteria are described in this paper.
Ayala-González
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Departamento de Vacunas Virales, Laboratorio Nacional de Salud Pública, México, D.F.
D004355:Drug Stability; D008458:Measles Vaccine / Q000592:standards*; D008459:Measles virus / Q000302:isolation & purification*; D010948:Viral Plaque Assay
D008458:Measles Vaccine
Pruebas de titulación y estabilidad de la vacuna antisarampionosa.