HLA antigens in Yugoslav population with rheumatoid arthritis.
The antigens of HLA-DR locus were determined in 127 patients with rheumatoid arthritis and in 175 healthy persons. The frequency of HLA-DR1 antigen was discovered in 45% of the patients and in 22.3% of the examinees from the control group (p less than 0.001). The relative risk is 2.84. 69% of the patients were seropositive. The HLA-DR4 antigen was found in 34% of the patients and in 21% of the healthy examinees (p less than 0.05). The relative risk is 1.91. The rheumatoid factor was determined in 70% of the patients with this antigen.
Department of Physical Medicine and Rheumatology, Medical Faculty University of Zagreb, Yugoslavia.
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Jajić
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Jajić
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Jajić
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Kerhin-Brkljacic
D000293:Adolescent; D000328:Adult; D001172:Arthritis, Rheumatoid / Q000276:immunology*; D005260:Female; D006684:HLA-DR Antigens / Q000302:isolation & purification*; D015798:HLA-DR1 Antigen / Q000302:isolation & purification; D015804:HLA-DR4 Antigen / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D012217:Rheumatoid Factor / Q000302:isolation & purification; D015022:Yugoslavia
D006684:HLA-DR Antigens; D015798:HLA-DR1 Antigen; D015804:HLA-DR4 Antigen; D012217:Rheumatoid Factor