[Increased survival rates of children with cystic fibrosis].
Seventy-two patients with cystic fibrosis were under care between January 1st 1972 and December 31st 1988, and 75 until now (July 1989). Fifty are alive, 24 died and 1 was lost to follow-up. The number of alive patients under control at the end of every year rose from 5 in 1972 up to 47 in 1988 and 50 at present. In order to assess the progress of survival rates, we compared two periods: 1972-1980 and 1981-1988. Twenty-eight were under control during the first period and 16 (57%) died, these figures for the second period being 55 and 8 (14%) (p 0.001) respectively. A remarkable increase in cumulative survival rates during the second period was observed at ages 1 (96% vs 68%), 5 (94% vs 55%) and 10 (86% vs 28%). Greater experience and closer follow-up, together with more aggressive treatment are likely to account for the increase in survival. It is vital that reference cystic fibrosis centers should be set-up in our country for the management of so complex a disease as 'cystic fibrosis.
Vázquez Cordero
C
C
Hospital Infantil de Cruces, Cruces-Baracaldo, Vizcaya.
Idígoras Ayastuy
G
G
Galardi Andonegui
M S
MS
Municio Martín
M A
MA
Aramburu Bardesi
N
N
Astigarraga Aguirre
I
I
Sojo Aguirre
A
A
Vitoria Cormezana
J C
JC
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000401:mortality* / Q000628:therapy; D006801:Humans; D007223:Infant; D013030:Spain / Q000453:epidemiology; D015996:Survival Rate
Aumento de la supervivencia en niños con fibrosis quística.