[Relation between the excitatory synaptic currents and clamped somatic potential in the model of neuron with nonlinear dendrites].
The influence of the clamped somatic potential on the excitatory synaptic current (EPSC) was studied in the model of the dendrite with N-shaped instantaneous stationary current--voltage curve. Proximal EPSC diminish and become narrower with decreasing hyperpolarization or modest depolarization, distal EPSC increase and become wider, intermediately distant EPSC change insignificantly. Under increasing depolarization all the EPSC become significantly wider and larger. EPSC facilitate stable depolarization of the dendrites. When the dendrite is stable depolarized EPSC becomes very small and narrow, but it becomes larger and wider as the soma is hyperpolarized. EPSC becomes especially large and wide when the soma is hyperpolarized just to terminate the stable depolarization of the dendrite branch where the active synapses are located. The model explains certain phenomena which are difficult to understand by the theory of ohmic dendrites. New phenomena are predicted.
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Baginskas
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Gutman
D003712:Dendrites / Q000502:physiology*; D004558:Electric Stimulation; D006801:Humans; D008564:Membrane Potentials; D008959:Models, Neurological; D009474:Neurons / Q000502:physiology* / Q000648:ultrastructure; D013569:Synapses / Q000502:physiology*
Zavisimost' vozbuzhdaiushchikh sinapticheskikh tokov ot fiksirovannogo potentsiala somy na modeli neĭrona s nelineĭnymi dendritami.