Whole gut irrigation and Prepacol laxative preparation for colonoscopy: a comparison.
Two techniques for preparation of the colon for colonoscopy were compared in a controlled trial. Fifty patients given a low residue diet and the laxative Prepacol were compared with 50 patients given whole gut irrigation. Significantly more patients suffered from vomiting (P = 0.0005), shivering (P = 0.0062) and nausea (P = 0.031) following irrigation; in two cases the procedure had to be abandoned because of profuse vomiting. Irrigation was less well tolerated by the patients (P = 0.00002) than preparation with Prepacol. On the other hand, the quality of bowel preparation was found to be better (P = 0.0005) after irrigation. On two occasions colonoscopy was not possible following Prepacol preparation because of faecal residue. Patients with a previous colorectal resection showed a similar quality of cleansing to those patients prepared with irrigation. We conclude that Prepacol is as efficient as irrigation for patients who have had a previous colorectal resection because the quality of bowel preparation is as good and the associated patient discomfort is small.
II. Department of Surgery, University of Cologne, FRG.
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Köhler
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Vestweber
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Mennigen
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Sommer
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Troidl
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001726:Bisacodyl / Q000008:administration & dosage; D002400:Cathartics / Q000008:administration & dosage*; D003113:Colonoscopy; D005260:Female; D006801:Humans; D007422:Intestines; D008297:Male; D008875:Middle Aged; D010710:Phosphates / Q000008:administration & dosage; D016032:Randomized Controlled Trials as Topic; D007507:Therapeutic Irrigation; D013997:Time Factors
D002400:Cathartics; D010710:Phosphates; C063635:prepacol; D001726:Bisacodyl