The use of autologous fibronectin in the surgical repair of through-and-through furcation lesions in man. A pilot study.
4 subjects with bilateral through-and-through mandibular furcation lesions were assessed for the healing response in terms of attachment gain following surgical debridement, root planing, citric acid demineralisation and topical application of autologous fibronectin. The results were compared with sham-operated and saline-treated contra-lateral sites. There was no significant difference in the attachment gain at sites treated with autologous fibronectin and citric acid compared with sites treated with citric acid alone.
Department of Preventive Dentistry, University of Sydney, Westmead Hospital, NSW, Australia.
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Yeung
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Boyatzis
D001861:Bone Regeneration / Q000187:drug effects; D002951:Citrates / Q000627:therapeutic use; D019343:Citric Acid; D002986:Clinical Trials as Topic; D012534:Dental Scaling; D005353:Fibronectins / Q000627:therapeutic use*; D006801:Humans; D010510:Periodontal Diseases / Q000188:drug therapy / Q000601:surgery*; D010865:Pilot Projects; D014092:Tooth Root / Q000601:surgery*
D002951:Citrates; D005353:Fibronectins; D019343:Citric Acid