Synthesis of [ring B-13C6] diosmin.
End products of flavone metabolism are phenolic acids, originating from rings B and C2 and/or C3 of ring C. Several of them are also endogenous products. Synthesis of uniformly labeled ring B-13C-diosmin [5] was performed for the unambiguous distinction, by ms, between endogenous and exogenous phenolic acids.
Centre CNRS INSERM de Pharmacologie-Endocrinologie, Montpellier, France.
B
B
Dulcire
P F
PF
Winternitz
D002247:Carbon Isotopes; D004145:Diosmin / Q000096:biosynthesis*
D002247:Carbon Isotopes; D004145:Diosmin