Haemolytic uraemic syndrome with shigella.
A 49-year-old male developed bloody diarrhoea whilst on a visit to India. Sigmoidoscopy and rectal biopsy showed acute colitis. Shigella dysentery type I was isolated from stool culture. Cytotoxin production by the organism was demonstrated. The patient developed acute renal failure, thrombocytopaenia and microangiopathic haemolytic anaemia. He required mechanical ventilation, haemodialysis, blood transfusion and antibiotic therapy and achieved a complete recovery. This is an unusual case of haemolytic uraemic syndrome complicating shigellosis in an adult.
O'Riordan
T
T
Department of Gastroenterology, Meath Hospital, Dublin.
Kavanagh
P
P
Mellotte
G
G
Conneally
E
E
Mulvihill
E
E
Keogh
J A
JA
Moráin
C O
CO
D002444:Cefuroxime / Q000031:analogs & derivatives / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004405:Dysentery, Bacillary / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D005440:Fluid Therapy; D006463:Hemolytic-Uremic Syndrome / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012762:Shigella dysenteriae
D002939:Ciprofloxacin; D002444:Cefuroxime; D006854:Hydrocortisone; C040738:cefuroxime axetil