Problems with clinical trials in general practice--a double-blind comparison of cream containing miconazole and hydrocortisone with hydrocortisone alone in the treatment of intertrigo.
A double-blind comparative study between 1% hydrocortisone cream and a combination of 1% hydrocortisone cream and 2% miconazole cream has highlighted some of the problems with this type of research in general practice. The collection of adequate patient numbers within a predefined time scale proved a major problem. However, the study demonstrated the safety and efficacy of both these preparations in the treatment of intertrigo.
K
K
Hedley
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P
Tooley
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H
Williams
D004311:Double-Blind Method; D004338:Drug Combinations; D005194:Family Practice; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use*; D007402:Intertrigo / Q000188:drug therapy*; D008297:Male; D008825:Miconazole / Q000627:therapeutic use*; D015337:Multicenter Studies as Topic; D009824:Ointments; D016032:Randomized Controlled Trials as Topic
D004338:Drug Combinations; D009824:Ointments; D008825:Miconazole; D006854:Hydrocortisone