Maternal platelet antibody levels in neonatal isoimmune thrombocytopenia.
A case of neonatal isoimmune thrombocytopenia (NIT) is described in which maternal platelet antibody levels decreased during the course of pregnancy. It is suggested that if this disorder is clinically suspected, maternal serum should be assessed for anti-platelet specificity using immunoblot analysis.
Department of Pathology, Medical University of South Carolina, Charleston 29425.
J
J
Lazarchick
R
R
Russell
B
B
Horn
D000328:Adult; D001792:Blood Platelets / Q000276:immunology*; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007231:Infant, Newborn; D007518:Isoantibodies / Q000032:analysis*; D008431:Maternal-Fetal Exchange / Q000276:immunology*; D011247:Pregnancy; D013921:Thrombocytopenia / Q000151:congenital / Q000276:immunology*
D007518:Isoantibodies