Antiphospholipid antibodies: more than just a disease marker?
Considerable interest has arisen over the past few years in a clinical syndrome characterized by a tendency to arterial or venous thrombosis, and the presence in the serum of antibodies to anionic phospholipids. In this article, Charles Mackworth-Young reviews the clinical features of this so-called 'anti-phospholipid syndrome', the characteristics of the anti-phospholipid response and the evidence for a possible role for these antibodies in pathogenesis.
Mackworth-Young
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Rheumatology Unit, Royal Postgraduate Medical School, Hammersmith Hospital, London.
D000818:Animals; D001323:Autoantibodies / Q000097:blood / Q000276:immunology*; D001327:Autoimmune Diseases / Q000209:etiology*; D015415:Biomarkers / Q000097:blood; D006801:Humans; D010743:Phospholipids / Q000276:immunology*; D013577:Syndrome
D001323:Autoantibodies; D015415:Biomarkers; D010743:Phospholipids