[Role of magnetic resonance spectroscopy in the diagnosis of ischemic cerebrovasculopathy].
NMR is still considered essentially, in the field of ischemic brain vascular disease, an imaging method. On the contrary, Authors review MR-spectroscopy possibilities, emphasizing that by this method it is possible to achieve a complete and dynamic study of brain energy metabolism, and therefore to identify markers of cellular injury clearly more sensitive and precocious than MRI morphological findings. Moreover, this method allows to easily evaluate cerebral blood flow, pharmacologic treatment efficacy, effects of eventual metabolic abnormalities on ischemia's evolution.
Cacciafesta
M
M
Istituto di I Clinica medica, Università La Sapienza, Roma.
Marigliano
V
V
Piccirillo
G
G
Brioli
D
D
Scuteri
A
A
Campana
F
F
Ferretti
F
F
D000818:Animals; D002545:Brain Ischemia / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism; D002560:Cerebrovascular Circulation; D005947:Glucose / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006943:Hyperglycemia / Q000150:complications / Q000378:metabolism; D007474:Ion Exchange; D007773:Lactates / Q000378:metabolism; D009682:Magnetic Resonance Spectroscopy; D008563:Membrane Lipids / Q000378:metabolism; D010758:Phosphorus / Q000378:metabolism; D012727:Sex Characteristics
D007773:Lactates; D008563:Membrane Lipids; D010758:Phosphorus; D005947:Glucose
Ruolo della spettroscopia-MR nella diagnostica delle cerebrovasculopatie ischemiche.