[Detection of respiratory allergies using the Phadiatop test in children 1 to 6 years of age].
Phadiatop, a new test for detecting hypersensitivity to airborne allergens, was used in 83 children aged 9 months to 6 years with recurrent respiratory manifestations, i.e. recurrent expiratory obstruction and/or recurrent respiratory infections. A good correlation was found between this test and both the prick tests (95%) and the specific IgE assays (91% for RASTS of classes greater than or equal to 1, and 95% for RASTS of classes greater than or equal to 2). However, the correlation was less strong with the total IgE level (68%). The overall correlation with the specialist's prediction based on history and physical evaluation was excellent (94%). In this study, Phadiatop was found to have a 90% sensitivity and a 98% specificity. Furthermore, this test costs 40% less than the often used strategy combining skin tests and determinations of total and specific IgE levels. In the age group studied, Phadiatop is most useful above the age of two, since in younger patients true respiratory allergies are fairly infrequent in recurrent ENT and lower respiratory tract infections, whereas infections are far more common.
Unité des Maladies Respiratoires et Allergiques de l'Enfant et de l'Adolescent, CHU Rangueil, Toulouse.
G
G
Dutau
F
F
Bremont
M
M
Hoff
P
P
Nouilhan
V
V
Moisan
G
G
Campistron
H
H
Regis
D002648:Child; D002675:Child, Preschool; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis*; D007159:Immunologic Tests / Q000295:instrumentation / Q000592:standards*; D007223:Infant; D008297:Male; D008403:Mass Screening / Q000295:instrumentation; D011852:Radioallergosorbent Test / Q000592:standards; D012130:Respiratory Hypersensitivity / Q000097:blood* / Q000453:epidemiology / Q000276:immunology; D012680:Sensitivity and Specificity; D012882:Skin Tests / Q000379:methods
D007073:Immunoglobulin E
Le dépistage de l'allergie respiratoire par le Phadiatop chez l'enfant de un à six ans.