Silicone breast implants--is there cause for concern?
Recent controversy has arisen regarding the potential carcinogenesis of medical silicone-gel as used in breast implants. A review of the pertinent literature shows that although rodents do demonstrate the development of sarcomas to any inert material, including silicone-gel, the phenomenon is species specific. No clinical evidence of carcinogenesis in humans has been noted in more than 25 years of use. We conclude that silicone-gel breast implants are safe.
Van Natta
B W
BW
Indianapolis Plastic Surgeons, IN 46260.
Thurston
J B
JB
Moore
T S
TS
D000818:Animals; D001940:Breast / Q000601:surgery*; D002273:Carcinogens; D005260:Female; D006801:Humans; D019736:Prostheses and Implants / Q000009:adverse effects*; D012377:Rodentia; D012828:Silicones / Q000633:toxicity*; D013518:Surgery, Plastic
D002273:Carcinogens; D012828:Silicones