Recruitment: the ins and outs of spindle pole formation.
Microtubule-organizing centers are a diverse but interrelated set of cellular organelles that appear when needed at specific times in the cell cycle. Diversity is introduced into MTOCs, and thus into microtubule structures, by post-translational modification, by morphological changes, by de novo synthesis, and by recruitment of cytoplasmic proteins. Understanding the mechanisms that lead to such diversity should contribute to a better understanding of the myriad of cellular events which depend on microtubules.
Leslie
R J
RJ
Department of Zoology, University of California, Davis 95616.
D000818:Animals; D002453:Cell Cycle / Q000502:physiology; D006801:Humans; D008870:Microtubules / Q000378:metabolism / Q000502:physiology; D015388:Organelles / Q000502:physiology; D008941:Spindle Apparatus / Q000378:metabolism / Q000502:physiology*