[Osteoporosis as a cause of pathological fractures].
More than a fifth of all females suffer from the risk to develop spinal osteoporosis. Hip fractures occur about 50,000 times per year in Federative Republic of Germany, about 1/3 in males and 2/3 in females. Estrogen deficiency is a risk factor of major importance for females; both sexes gain risk because of nutritional calcium deficiency and reduced mobility. Estrogen replacement therapy was proven to reduce the risk in females; and calcium supply reduces risk in both sexes. Therapy of developed spinal osteoporosis includes fluorides, calcium, vitamin D and calcitonin. No drug therapy has been developed so far for patients with senile osteoporosis and hip fractures.
Minne
H W
HW
Abteilung Innere Medizin I, Universitätskliniken Heidelberg.
D000368:Aged; D002118:Calcium / Q000627:therapeutic use; D015914:Estrogen Replacement Therapy; D005260:Female; D005459:Fluorides / Q000627:therapeutic use; D005598:Fractures, Spontaneous / Q000209:etiology* / Q000517:prevention & control; D006620:Hip Fractures / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D015663:Osteoporosis, Postmenopausal / Q000150:complications; D013122:Spinal Diseases / Q000517:prevention & control
D005459:Fluorides; D002118:Calcium
Die Osteoporose als Ursache der pathologischen Fraktur.