[A gene inhibiting the development of human retinoblastoma: the prototype of tumor suppressor genes].
One of the most important progress in cancer research of our time is the discovery of protooncogenes, oncogenes and tumor suppressor genes. The authors review the isolation, of the human retinoblastoma (Rb) susceptibility gene, the analysis of Rb protein and their role in the pathogenesis of retinoblastoma and other tumors.
Debreceni Orvostudományi Egyetem, Közegészségtani és Járványtani Intézete.
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Uzvölgyi
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Kertai
D005134:Eye Neoplasms / Q000235:genetics*; D006801:Humans; D009857:Oncogenes / Q000235:genetics*; D012175:Retinoblastoma / Q000235:genetics*; D013489:Suppression, Genetic / Q000235:genetics*
Az emberi retinoblastoma kifejlödését gátló gén: a tumor szuppresszor gének prototípusa.