[Significance of the captopril test in the diagnosis of primary hyperaldosteronism --apropos of 4 clinical cases].
We describe four cases of primary hyperaldosteronism whose initial presentation was a moderate to severe hypertension. In three patients an adrenal adenoma was found; in another patient was due to unilateral adrenal hyperplasia. A good therapeutic response was achieved in all cases by unilateral adrenalectomy. The captopril test (Lyons version) proved useful to exclude essential hypertension and, may be, in distinguishing the new sub-types of primary hyperaldosteronism recently described. Indeed, only in the case of unilateral adrenal hyperplasia a fall in plasma aldosterone levels was observed. However, we feel that further investigation is needed to clarify this point.
Hospital de Curry Cabral, Serviço 1.
R
R
Proença
J
J
Machado
F
F
Maltez
M J
MJ
Alberto
G
G
Martins
P
P
Gonçalves
D000328:Adult; D000368:Aged; D000450:Aldosterone / Q000097:blood; D002216:Captopril; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000097:blood / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012083:Renin / Q000097:blood
D000450:Aldosterone; D002216:Captopril; D012083:Renin
O valor do teste do captopril no diagnóstico do hiperaldosteronismo primário--a propósito de 4 casos clínicos.