[The effect of cell migration on the stability of immunogenic multicentric tumors].
A mathematical model of the growth of multicentrical tumors under conditions of the tumor cells interactions with cytotoxic T-lymphocytes (CTL), natural resistant factors and cells and migration CTL between tumor focuses is presented. For any finite number of the tumor focuses at the comparatively low intensity migration of CTL the dynamic stability conditions among multicentrical tumors and the immune system were obtained.
Alekseeva
E I
EI
Kuznetsov
V A
VA
D002465:Cell Movement; D006801:Humans; D007113:Immunity, Innate; D008962:Models, Theoretical; D009378:Neoplasms, Multiple Primary / Q000276:immunology* / Q000473:pathology; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*
Vliianie migratsii kletok na stabil'nost' immunogennykh mul'titsentricheskikh opukholeĭ.