Microdialysis--a novel technique for clinical investigations.
Microdialysis is a novel, non-traumatic technique which, when properly performed, allows continuous direct measurements of substances in the interstitial space of a tissue or organ. It also makes it possible to obtain protein-free fluid for analyses, while contaminating bacteria or viruses are excluded. The measurements provide us with an insight into metabolic and pharmacological events at the cellular level in a target organ. Apart from its usefulness for experimental work, it is likely to become an important tool for defined areas in clinical practice.
Department of Medicine II, University of Göteborg, Sahlgren's Hospital, Sweden.
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Lönnroth
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Smith
D000818:Animals; D003956:Dialysis / Q000379:methods*; D005110:Extracellular Space / Q000032:analysis*; D006801:Humans