[Treatment of childhood anorexin with spleen deficiency by principle of invigorating spleen and benefiting qi].
101 children of anorexia with Spleen deficiency were divided randomly into two groups, the invigorating Spleen(IS) group of 58 cases treated by modified Yi-Gong-San, and the replenishing zinc(RZ) group of 43 cases treated by 0.2% zinc sulphate syrup. One course of treatment was 3 months.


RESULTS
the clinical effects of IS group were notable in promoting appetite, increasing body weight and height, eliminating polyhidrosis, preventing common cold and tracheitis etc. The total effective rate was 96.6% in IS group which was significantly better than 72.1% in the RZ group (P less than 0.01). The effect of examination showed that the levels of hair zinc after treatment were markedly increased in both groups (P less than 0.01). The average increased value of hair zinc was 62.2 +/- 9.1 (ppm) in IS group which was higher than 42.1 +/- 7.2 (ppm) in RZ group (P less than 0.05). Moreover excretion rate and Hb after treatment in the IS group were markedly higher those in the RZ group (P less than 0.01). Chemical analysis showed that the concentration of zinc in modified Yi-Gong-San was very slight (0.73 mg/pack). It indicated that arising hair zinc in IS group was not simply supply of zinc but also the treatment in appetite, digestion and absorption, with which the body was supplied enough zinc naturally by food taken.
China-Japan Friendship Hospital, Beijing.
X M
XM
Li
B Y
BY
Wang
Z W
ZW
Zhou
D000855:Anorexia / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006197:Hair / Q000378:metabolism / Q000648:ultrastructure; D006801:Humans; D007223:Infant; D008297:Male; D008516:Medicine, Chinese Traditional; D013158:Splenic Diseases / Q000188:drug therapy; D015032:Zinc / Q000378:metabolism
D004365:Drugs, Chinese Herbal; D015032:Zinc