Duplex ultrasound analysis of operated carotid arteries in baboons.
Duplex ultrasound analysis, which combines high-resolution B-mode imaging and Doppler spectral flow analysis, was used to examine 3 to 4 mm in diameter normal [n = 24] and mechanically manipulated baboon carotid arteries (endarterectomies [n = 10], construction of interposition vascular grafts [n = 10], and placement of endovascular stents within interposition grafts [n = 4]). Patency or occlusion was definitively confirmed by direct visualization and palpation during surgical exploration at defined intervals or by postmortem histologic examination. Duplex examination accurately demonstrated postoperative hemodynamic changes and with only one exception correctly identified patency and occlusion. We conclude that this technique is superior to more invasive methods for verification of the outcome of operations on small arteries in experimental animals.
Bass
A
A
Department of Basic Clinical Research, Scripps Clinic and Research Foundation, La Jolla, California.
Kelly
A B
AB
Otis
S M
SM
Hanson
S R
SR
Torruella
A
A
Harker
L A
LA
Krupski
W C
WC
D000818:Animals; D001783:Blood Flow Velocity; D002339:Carotid Arteries / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D004691:Endarterectomy; D006439:Hemodynamics; D008297:Male; D010215:Papio; D011183:Postoperative Complications / Q000175:diagnosis*; D015607:Stents; D014463:Ultrasonography; D014654:Vascular Patency