[A possibility of significant lowering the defibrillation current by determining the right time for application of a defibrillating pulse. A mathematical model].
The effect of defibrillating pulses on the functionally determined re-entries (leading circles) was studied by computer simulation. Arrhythmias caused by different numbers of leading circles (from 1 to 18) were investigated. The defibrillation threshold was found to vary 2-4-fold, depending on the time of application of a pulse. At small currents the defibrillation mechanism is principally different from the commonly known one and is linked to the movement of leading circles towards each other or towards the boundary of the excitable tissue.
Pertsov
A M
AM
Biktashev
V N
VN
Ermakova
E A
EA
Krinskiĭ
V I
VI
D001145:Arrhythmias, Cardiac / Q000503:physiopathology / Q000628:therapy*; D002304:Cardiac Pacing, Artificial; D004554:Electric Countershock; D006801:Humans; D008962:Models, Theoretical
O vozmozhnosti znachitel'nogo ponizheniia toka defibrilliatsii pri pravil'nom vybore momenta naneseniia defibrilliruiushchego impul'sa. Matematicheskaia model'.