High-performance immunoaffinity chromatography for drug residue analysis.
High-performance immunoaffinity chromatography (IAC) is a potentially strong analytical tool for measurement of drug residues in various matrixes. Although the use of Immunoaffinity separations is not new, the application to drug residue analysis is in its infancy. The present paper discusses the production and purification of antibody, the preparation of columns, the theoretical basis of the analytical separation and elution, and variations of the analytical approach.
Katz
S E
SE
Rutgers University, Cook College, Department of Biochemistry and Microbiology, New Brunswick, New Jersey 08903.
Brady
M S
MS
D000818:Animals; D002846:Chromatography, Affinity; D004350:Drug Residues / Q000032:analysis*; D007120:Immunochemistry