[Immunohistological study of pulmonary adenocarcinoma using monoclonal antibodies].
Immunohistochemical methods were used to identify A2F4 monoclonal antibodies raised by immunization of animals with a human lung adenocarcinoma cell line in 17 lung adenocarcinomas and five pulmonary metastases of other origin. The antigen identified by the antibodies was registered in 53% of lung adenocarcinomas. Localization of the pulmonary antigen was compared with that of the carcinoembryonic antigen. The expression of the antigens proved different.
K K
KK
Pugachev
S G
SG
Egorova
N V
NV
Vial'tsev
I B
IB
Shimbireva
I D
ID
Kokhanova
D000230:Adenocarcinoma / Q000175:diagnosis*; D000818:Animals; D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm / Q000032:analysis; D002272:Carcinoembryonic Antigen / Q000032:analysis; D006801:Humans; D007124:Immunoenzyme Techniques; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000556:secondary; D051379:Mice; D008807:Mice, Inbred BALB C; D014407:Tumor Cells, Cultured
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D002272:Carcinoembryonic Antigen
Immunogistologicheskoe izuchenie adenokartsinomy legkogo s pomoshch'iu monoklonal'nykh antitel.