A prospective randomized study of saline solution amnioinfusion.
We performed a prospective randomized study of saline solution amnioinfusion in four types of pregnancy complications: postterm pregnancy, variable decelerations in labor, preterm labor, and oligohydramnios-suspected growth retardation. A total of 100 patients were randomized, 43 to undergo amnioinfusion and 57 to be in a control group. Patients undergoing amnioinfusion had a significantly decreased incidence of postpartum endometritis (2.4% vs 19%, p = 0.01) and a lower incidence of cesarean delivery that was due to fetal distress in labor (4.7% vs 16%, p = 0.07). The use of amnioinfusion also made a significant contribution to the four-quadrant ultrasonographic estimate of amniotic fluid volume (14.7 vs 9.8 cm, p less than 0.001). All other maternal and neonatal outcome parameters were similar between the two groups. We conclude that saline solution amnioinfusion in labor may be a beneficial procedure but that further studies are needed.
Department of Obstetrics and Gynecology, University of Alabama, Birmingham 35294.
J
J
Owen
B V
BV
Henson
J C
JC
Hauth
D000293:Adolescent; D000328:Adult; D000650:Amnion; D000653:Amniotic Fluid / Q000378:metabolism; D002585:Cesarean Section; D004716:Endometritis / Q000517:prevention & control; D005260:Female; D005316:Fetal Distress / Q000517:prevention & control; D006801:Humans; D007263:Infusions, Parenteral / Q000379:methods; D007744:Obstetric Labor Complications / Q000517:prevention & control*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011273:Pregnancy, Prolonged; D011446:Prospective Studies; D011645:Puerperal Infection / Q000517:prevention & control; D011897:Random Allocation; D012965:Sodium Chloride / Q000008:administration & dosage / Q000627:therapeutic use*; D014463:Ultrasonography
D012965:Sodium Chloride