The clinical use of cocaine in rhinosurgery: a case-report and a review.
Three patients with adverse reactions of the nasal mucosa after topical anaesthesia with crystalline cocaine in combination with adrenaline are described. The current knowledge of the pharmacology of cocaine is summarized. The systemic and local reactions and side-effects of cocaine as topical anaesthetic in rhinosurgery are reviewed.
Dept. of O.R.L., University Hospital Utrecht, The Netherlands.
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Albers
D000328:Adult; D003042:Cocaine / Q000009:adverse effects* / Q000493:pharmacokinetics; D006801:Humans; D009297:Nasal Mucosa / Q000187:drug effects*; D015508:Nasal Obstruction / Q000601:surgery; D009666:Nose / Q000601:surgery*
D003042:Cocaine