Suxamethonium and hyperkalaemia.
Severe life-threatening hyperkalaemia may occur following administration of suxamethonium during certain periods after burns, neurological injuries, and in certain other conditions. Although this response is well-known, there is disagreement about when it may occur. This review describes the normal hyperkalaemic response to suxamethonium, the factors affecting it, the conditions in which it may be exaggerated, and the periods of high risk.
Anaesthetic Department, Royal Marsden Hospital, London, England.
S M
SM
Yentis
D000818:Animals; D002056:Burns / Q000503:physiopathology; D006323:Heart Arrest / Q000209:etiology; D006801:Humans; D006947:Hyperkalemia / Q000139:chemically induced*; D007239:Infections / Q000503:physiopathology; D009422:Nervous System Diseases / Q000503:physiopathology; D013390:Succinylcholine / Q000009:adverse effects* / Q000633:toxicity; D020196:Trauma, Nervous System; D014511:Uremia / Q000503:physiopathology
D013390:Succinylcholine