[Analysis of methodological approach to the evaluation of toxicity of complex mixtures of relatively constant composition used in industry (review of the literature)].
Basing on literature data and the author's personal experience, the article displays current approaches to the toxicological assessment of industrial complex mixtures with permanent compositions. These include two main approaches to the detection of major components: a) the establishment of the individual substances ratio in the toxicological parameters, and b) the application of the regression coefficients and their derivatives. Toxicity assessment against the toxicological parameters of individual substances is also substantiated.
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EA
Blinova
D000395:Air Pollutants, Occupational / Q000032:analysis / Q000633:toxicity*; D004338:Drug Combinations; D005740:Gases / Q000008:administration & dosage / Q000737:chemistry / Q000592:standards / Q000633:toxicity*; D006801:Humans; D008452:Maximum Allowable Concentration; D014116:Toxicology / Q000379:methods* / Q000592:standards; D014586:USSR
D000395:Air Pollutants, Occupational; D004338:Drug Combinations; D005740:Gases
K analizu metodologicheskikh podkhodov pri otsenke toksichnosti slozhnykh smeseĭ otnositel'no postoiannogo sostava dlia usloviĭ promyshlennykh predpriiatiĭ (obzor literatury).