High levels of circulating met-enkephalin in pregnant and menstruating type 1 diabetic women.
Plasma met-enkephalin (MET-ENK) levels are increased in type 1 diabetic women and in pregnant diabetic women in comparison with normal women. Plasma MET-ENK levels further increase in the peripartum period both in diabetic and non-diabetic females, probably due to the analgesic and behavioural properties of the opioid system.
Istituto di II Clinica Medica, University La Sapienza, Rome, Italy.
M
M
Negri
F
F
Fallucca
G
G
Tonnarini
P
P
Mariani
M
M
D'Alessandro
A
A
Pachì
D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D004744:Enkephalin, Methionine / Q000097:blood*; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D008597:Menstrual Cycle / Q000097:blood; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000097:blood*; D011388:Prolactin / Q000097:blood
D007328:Insulin; D004744:Enkephalin, Methionine; D011388:Prolactin