Variant angina due to deficiency of intracellular magnesium.
A 51-year-old man was diagnosed as having variant angina by documentation of typical ST elevation during anginal attack and also by showing coronary arterial spasm (#2 and #12) during hyperventilation on coronary arteriography. Large quantities of calcium blocking agents and nitrates could not improve his symptoms. Lack of intracellular magnesium was suspected from a daily excretion of urine magnesium (5.3 mEq) and magnesium tolerance test (56.7%). After hourly infusion of magnesium sulfate (80 mEq), coronary spasm could not be induced by ergonovine.
Second Department of Internal Medicine, St. Marianna University School of Medicine, Kanagawa, Japan.
K
K
Tanabe
K
K
Noda
M
M
Kamegai
F
F
Miyake
T
T
Mikawa
M
M
Murayama
J
J
Sugai
D000788:Angina Pectoris, Variant / Q000209:etiology*; D003329:Coronary Vasospasm / Q000209:etiology; D004562:Electrocardiography; D006801:Humans; D008274:Magnesium / Q000652:urine; D008275:Magnesium Deficiency / Q000150:complications* / Q000652:urine; D008297:Male; D008875:Middle Aged
D008274:Magnesium