Therapeutic response to a dermatologic patch and betamethasone valerate 0.1 percent cream in the management of chronic plaques in psoriasis.
The efficacy of a hydrocolloid dermatologic patch (Actiderm) in conjunction with topical beta-methasone valerate 0.1 percent cream was studied in outpatients with chronic plaque-type psoriasis treated for three weeks, and observed for an additional two weeks after therapy. A significant degree (p less than 0.05) of lesion resolution occurred at the site treated with the dermatologic patch plus steroid cream, whereas sites treated with either agent alone showed mild but insignificant change. It was concluded that the patch was a highly effective adjunct in the treatment of chronic plaques of psoriasis.
Wilkinson
R D
RD
Royal Victoria Hospital, Montreal, Quebec, Canada.
Ohayon
M
M
D000287:Administration, Topical; D000328:Adult; D000368:Aged; D001623:Betamethasone / Q000031:analogs & derivatives*; D001624:Betamethasone Valerate / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D003102:Colloids; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009779:Occlusive Dressings; D011565:Psoriasis / Q000473:pathology / Q000628:therapy*
D003102:Colloids; D001623:Betamethasone; D001624:Betamethasone Valerate