New approaches to body composition research: a reexamination of two-compartment model assumptions.
The field of human body composition research by necessity is based upon assumptions related to tissue chemical content. The 2-compartment model, which requires only 1 measurement in addition to body weight, is the cornerstone of current research in this field. Yet the assumptions upon which 2-compartment models are based were developed on a limited scale and their validity under specified conditions is questionable. Recent developments now allow quantification of previously unmeasured somatic constituents. The capacity to extend our models to 4 or more components is now at hand. Not only will this allow us to vastly expand our validation of two 2-compartment approaches, but our ability to explore new and important physiological questions is within reach.
Department of Medicine, Columbia University College of Physicians and Surgeons, St. Luke's-Roosevelt Hospital Center, New York.
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Heymsfield
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Lichtman
D000273:Adipose Tissue / Q000502:physiology*; D000328:Adult; D001823:Body Composition / Q000502:physiology*; D015992:Body Mass Index; D001834:Body Water / Q000502:physiology*; D001835:Body Weight / Q000502:physiology; D006801:Humans; D008903:Minerals / Q000378:metabolism
D008903:Minerals