Appetite regulation by gut peptides.
A number of gastrointestinal hormones that are released from the gut in response to intraluminal food stuffs have been shown to play a role in producing satiety. Some of these hormones apparently activate ascending vagal fibers that send messages to the nucleus tractus solitarius, and perhaps from there messages are sent to the paraventricular nucleus of the hypothalamus. Not only do gastrointestinal hormones play a role in the termination of a meal but they also appear to modulate energy metabolism (at least in rodents) through the activation of brown adipose tissue.
Geriatric Research Education and Clinical Center, St. Louis Veterans Administration Medical Center, Missouri.
J E
JE
Morley
D000818:Animals; D001069:Appetite Regulation / Q000502:physiology*; D002766:Cholecystokinin / Q000502:physiology*; D004285:Dogs; D004734:Energy Metabolism / Q000502:physiology; D005768:Gastrointestinal Hormones / Q000502:physiology*; D006801:Humans; D008253:Macaca mulatta; D051381:Rats; D012528:Satiety Response / Q000502:physiology
D005768:Gastrointestinal Hormones; D002766:Cholecystokinin