Renin-secreting retroperitoneal leiomyosarcoma: an unusual cause of hypertension.
A 41 year old man with severe hypertension due to a renin-secreting retroperitoneal leiomyosarcoma is described. Clinical, immunohistochemical, electron microsopic and autopsy findings are presented. The origin of juxtaglomerular cells from vascular smooth muscle is briefly discussed.
Department of Histopathology, Freeman Hospital, Newcastle-upon-Tyne, UK.
P M
PM
Geddy
J
J
Main
D000328:Adult; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D007890:Leiomyosarcoma / Q000150:complications / Q000378:metabolism*; D008297:Male; D012083:Renin / Q000378:metabolism*; D012186:Retroperitoneal Neoplasms / Q000150:complications / Q000378:metabolism*
D012083:Renin