Histamine receptors: subclasses and specific ligands.
In this review the three main types of histamine receptors are discussed together with their specific ligands. For the classical H1-receptors much emphasis is put on the mechanism by which the receptor is stimulated. For the H1- and H2-receptor the review includes information on the several models available for establishing agonistic or antagonistic activity. In the section on the H3-receptor the ligands are discussed as well as the possible physiological role of this receptor. In the final paragraphs some less well defined activities are presented.
Haaksma
E E
EE
Department of Pharmacochemistry, Faculty of Chemistry, Vrije Universiteit, Amsterdam, The Netherlands.
Leurs
R
R
Timmerman
H
H
D000818:Animals; D006801:Humans; D008024:Ligands; D011968:Receptors, Histamine / Q000145:classification / Q000378:metabolism / Q000502:physiology
D008024:Ligands; D011968:Receptors, Histamine