Effect of fenugreek seeds on blood glucose and serum lipids in type I diabetes.
The effect of fenugreek seeds (Trigonella foenum graecum) on blood glucose and the serum lipid profile was evaluated in insulin-dependent (Type I) diabetic patients. Isocaloric diets with and without fenugreek were each given randomly for 10 d. Defatted fenugreek seed powder (100 g), divided into two equal doses, was incorporated into the diet and served during lunch and dinner. The fenugreek diet significantly reduced fasting blood sugar and improved the glucose tolerance test. There was a 54 per cent reduction in 24-h urinary glucose excretion. Serum total cholesterol, LDL and VLDL cholesterol and triglycerides were also significantly reduced. The HDL cholesterol fraction, however, remained unchanged. These results indicate the usefulness of fenugreek seeds in the management of diabetes.
National Institute of Nutrition, Indian Council of Medical Research, Hyderabad.
R D
RD
Sharma
T C
TC
Raghuram
N S
NS
Rao
D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000178:diet therapy* / Q000188:drug therapy; D003927:Diet, Diabetic; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D007194:India; D007328:Insulin / Q000627:therapeutic use; D008055:Lipids / Q000097:blood*; D008297:Male; D010946:Plants, Medicinal; D011897:Random Allocation; D012639:Seeds; D012959:Socioeconomic Factors
D001786:Blood Glucose; D007328:Insulin; D008055:Lipids