Treatment of induced enterotoxigenic colibacillosis (scours) in calves by the lactoperoxidase system and lactoferrin.
The clinical efficacy of a preparation based on the lactoperoxidase system (LP-s) and lactoferrin (LF) was tested in calves experimentally infected with E coli K99+, Ent+. Mortality, occurrence and duration of diarrhoea were significantly lower (P less than 0.05) and general clinical status significantly better (P less than 0.05) in infected calves treated with LP-s and LF preparation than in infected but non-treated calves. Results suggest that LP-s and lactoferrin are effective in the treatment of enteric colibacillosis in calves.
Medical University of Southern Africa, Faculty of Veterinary Science, Medunsa, Republic of South Africa.
J
J
Still
P
P
Delahaut
P
P
Coppe
A
A
Kaeckenbeeck
J P
JP
Perraudin
D000818:Animals; D001835:Body Weight; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy*; D003967:Diarrhea / Q000188:drug therapy / Q000662:veterinary*; D004359:Drug Therapy, Combination; D004927:Escherichia coli Infections / Q000188:drug therapy / Q000662:veterinary*; D005243:Feces / Q000382:microbiology; D005947:Glucose / Q000627:therapeutic use; D005949:Glucose Oxidase / Q000627:therapeutic use; D007781:Lactoferrin / Q000627:therapeutic use*; D007782:Lactoglobulins / Q000627:therapeutic use*; D007784:Lactoperoxidase / Q000627:therapeutic use*; D010544:Peroxidases / Q000627:therapeutic use*; D011897:Random Allocation; D013861:Thiocyanates / Q000627:therapeutic use
D007782:Lactoglobulins; D013861:Thiocyanates; D005949:Glucose Oxidase; D007784:Lactoperoxidase; D010544:Peroxidases; D007781:Lactoferrin; D005947:Glucose