Inefficacy of single-dose nifedipine in the treatment of phobic anxiety.
Single-dose nifedipine was given to 13 phobic patients with increased generalized anxiety. Nifedipine failed to demonstrate anxiety-reducing effects on baseline anxiety ratings. Furthermore, in a subset of four patients, the drug failed to show an anxiolytic effect in exposure-related anxiety.
Department of Psychiatry, Rambam Medical Center, Haifa, Israel.
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Klein
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Geraci
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Uhde
D001143:Arousal / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D006801:Humans; D009543:Nifedipine / Q000008:administration & dosage*; D010698:Phobic Disorders / Q000188:drug therapy* / Q000523:psychology
D009543:Nifedipine