[The efficacy of the captopril treatment of elderly hypertension patients].
It was established that monotherapy with captopril was effective in 72% of patients with hypertensive disease in the elderly. Reduction of the arterial pressure is accompanied by an improvement of the indices of hemodynamics and myocardial contractility as well as relaxation of the left ventricle. Captopril proved more effective in patients with a high concentration of blood angiotensin. Acute load by a single intake of 25 mg of captopril may with high probability predict the efficacy of treatment courses, namely, in patients with a good clinical efficacy reduction of the preparation. Captopril is recommended for the treatment of hypertensive disease in the elderly.
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Korkushko
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MI
Fedirko
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Gidzinskaia
D000368:Aged; D000804:Angiotensin II / Q000097:blood; D002216:Captopril / Q000009:adverse effects / Q000627:therapeutic use*; D004341:Drug Evaluation; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D008875:Middle Aged; D012083:Renin / Q000097:blood
D000804:Angiotensin II; D002216:Captopril; D012083:Renin
Effektivnost' lecheniia kaptoprilom bol'nykh gipertonicheskoĭ bolezn'iu pozhilogo vozrasta.