Ocular cicatricial pemphigoid.
A series of 17 patients with ocular cicatricial pemphigoid (OCP) is described retrospectively. The importance of early recognition, especially of disease involving the medial canthus and caruncular region, diagnosis by biopsy, and adequate immunosuppressive and surgical therapy, are emphasised. A detailed grading scheme has been developed and this has enabled the authors to determine the success or failure of the therapy during the active treatment period. A combined ophthalmological and immunological approach to treatment can result in a successful visual outcome of this potentially blinding disease.
Francis
I C
IC
Concord Hospital, Sydney, Australia.
McCluskey
P J
PJ
Walls
R S
RS
Wakefield
D
D
Brewer
J M
JM
D000368:Aged; D001706:Biopsy; D003228:Conjunctiva / Q000473:pathology; D003452:Cryosurgery; D005143:Eyelids / Q000601:surgery; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007136:Immunoglobulins / Q000378:metabolism; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D010390:Pemphigoid, Benign Mucous Membrane / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D011379:Prognosis; D012189:Retrospective Studies; D012872:Skin Diseases, Vesiculobullous / Q000175:diagnosis*
D007136:Immunoglobulins; D007166:Immunosuppressive Agents