[Exocrine function of the pancreas and pathological histology of the stomach in patients with stomach yin deficiency syndrome (SYDS) research on SYDS following abdominal operation or with severe acute abdominal diseases (Part 3)].
Exocrine function of pancreas (BT-PABA test) in 13 patients with SYDS was examined and gastric membrane in 5 cases with SYDS other than gastric diseases was observed under light- and electro-microscopy. The results were as follows: urine rate of recovery of PABA in SYDS was 35. 42 +/- 14.33% and that in the control with same age was 64.70 +/- 10.55%. The rate in SYDS was decreased obviously (P less than 0.001). Under light microscopy gastric mucosa of patients with SYDS showed slight gland degenerative atrophy, smaller cytoplasm, eosinophilic decrease of parietal cells and infiltration of inflammatory cells in interstitial tissue. Under electro-microscopy, the main changes of the gastric mucosa with SYDS were severe mitochondria damage, inflating rough endoplasmic pools and large vacuole at which membrane major particles of ribosomes disappeared, degenerated secretory vessels and formation of myelin figure in parietal cells, decrease of secretory particles in main cells, degeneration in some degree and decrease of nervous secretory particles in G cells and damaged interstitial capillaries. The results in this study suggested that the exocrine function of pancreas in patients with SYDS after abdominal operation or with severe acute abdominal diseases was decreased and there were some damages in energy supply and protein manufacturing systems of the gastric mucosa and functional disturbances of main cells, parietal cells and G cells in patients with SYDS.
Qi
Q H
QH
Dept. of Surgery, First Affiliated Hospital of Tianjing Medical College.
Wu
X Z
XZ
Bai
J W
JW
D010129:4-Aminobenzoic Acid; D000006:Abdomen, Acute / Q000503:physiopathology* / Q000601:surgery; D001649:Bile Duct Diseases / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D005753:Gastric Mucosa / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D010179:Pancreas / Q000378:metabolism*; D010189:Pancreatic Juice / Q000378:metabolism; D011184:Postoperative Period; D013270:Stomach / Q000473:pathology*
D010129:4-Aminobenzoic Acid