Analysis of proteolytic cleavage of recombinant TGF-beta 1: production of hybrid molecules with increased processing efficiency.
Madisen
L
L
Oncogen, Seattle, Washington 98121.
Lioubin
M N
MN
Farrand
A L
AL
Brunner
A M
AM
Purchio
A F
AF
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015153:Blotting, Western; D002460:Cell Line; D006224:Cricetinae; D004252:DNA Mutational Analysis; D006031:Glycosylation; D006801:Humans; D008360:Mannosephosphates / Q000378:metabolism; D008744:Methylamines / Q000494:pharmacology; D008969:Molecular Sequence Data; D008970:Molecular Weight; D010447:Peptide Hydrolases / Q000378:metabolism*; D010766:Phosphorylation; D011499:Protein Processing, Post-Translational / Q000187:drug effects; D011994:Recombinant Proteins; D015291:Transforming Growth Factors / Q000096:biosynthesis*
D008360:Mannosephosphates; D008744:Methylamines; D011994:Recombinant Proteins; D015291:Transforming Growth Factors; C027451:methylamine; D010447:Peptide Hydrolases