[Circadian analysis of sleep, rectal temperature and immunological and endocrinological variables in sleeping sickness: preliminary study].
A multidisciplinary study was conducted in 8 patients with neurological Human African Trypanosomiasis. The sleep-wake cycle followed an ultradian pattern which was more pronounced in patients with more severe symptoms. The EEG trace was consistently interrupted by numerous cyclic activation patterns with K complexes, rapid low amplitude elements and slow high voltage elements. Circadian rhythmicity was also disturbed in other physiological (rectal temperature), immunological (interleukins) or hormonal (cortisol, prolactin) variables, the disturbance being greater in severely hit patients.
Laboratoire de Physiologie, Faculté des Sciences de la Santé, Niamey, Niger.
R
R
Gati
F
F
Tabaraud
A
A
Buguet
J
J
Bert
P
P
Tapie
J
J
Bittel
B
B
Sparkes
J C
JC
Breton
F
F
Doua
P
P
Bogui
D000293:Adolescent; D000328:Adult; D000368:Aged; D001831:Body Temperature; D002940:Circadian Rhythm; D004562:Electrocardiography; D005260:Female; D006728:Hormones / Q000097:blood; D006801:Humans; D007375:Interleukin-1 / Q000097:blood; D008297:Male; D008875:Middle Aged; D012007:Rectum; D012890:Sleep / Q000502:physiology*; D014353:Trypanosomiasis, African / Q000503:physiopathology*
D006728:Hormones; D007375:Interleukin-1
Analyse circadienne du sommeil, de la température rectale et de variables immunologiques et endocrinologiques dans la maladie du sommeil: etude préliminaire.