[The DO2/VO2 relationship: and approach to cellular metabolism in "crisis" situations].
The relationship between the organism's oxygen consumption (VO2) and its transport to the cells (DO2), termed the DO2/VO2 relationship, has been the subject of many publications during the past decade. The pathological changes occurring in this relationship in intensive care patients has been much studied, and certain conclusions drawn with regard to monitoring and therapeutic goals. After a brief review of the pathophysiological mechanisms involved we examine the practical implications of the DO2/VO2 concept, focusing on the many methodological and interpretation problems raised.
Jolliet
P
P
Département d'anesthésiologie, Hôpital cantonal universitaire, Genève.
Pittet
J F
JF
Chevrolet
J C
JC
D000818:Animals; D001692:Biological Transport; D003422:Critical Care; D004285:Dogs; D006801:Humans; D007413:Intestinal Mucosa / Q000378:metabolism; D009132:Muscles / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D010100:Oxygen / Q000378:metabolism*; D010101:Oxygen Consumption; D010102:Oxygen Inhalation Therapy; D011659:Pulmonary Gas Exchange; D013997:Time Factors
D010100:Oxygen
La relation DO2/VO2: une approche du métabolisme cellulaire en cas de "crise".