[Study of cellular kinetics in oral leukoplakia].
The Authors aim was to study the Labeling Indices (LI) of 12 subjects with oral leukoplakia, using an in vitro labeling technique with tritiated thymidine (Silvestrini-Kit, Ribbon spa, Milan). Twelve volunteers of our Dental Clinic were enrolled in this study as a control group. The kinetic parameter was investigated by counting cells from autoradiographs on histological selections of the biopsies. By a Wilcoxon test, significant differences were found between the LI of the two groups: p = 0.00003. Finally, a comparison has also been made between LI of these lesions and the LI of oral squamous cell carcinomas.
Università degli Studi di Milano.
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D000328:Adult; D000368:Aged; D001345:Autoradiography; D014408:Biomarkers, Tumor; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D007972:Leukoplakia, Oral / Q000000981:diagnostic imaging / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D011877:Radionuclide Imaging
D014408:Biomarkers, Tumor
Studio della cinetica cellulare delle leukcoplachie orali.