Experimental intervention of hypertension and cardiovascular diseases.
Experimental prevention of hypertension and related cardiovascular diseases has been studied in rat models for hypertension and stroke and not only salt reduction but also increased intakes of potassium, calcium, magnesium, protein, some amino acids and fatty acids and dietary fibers have been proven to be effective and indicated the importance of nonpharmacological dietary prevention of cardiovascular diseases. These experimental findings contribute to dietary risk factor analyses and the prevention of hypertension and its complications in man, as demonstrated by a cross-sectional epidemiological study on cardiovascular diseases and alimentary comparison (WHO-CARDIAC Study).
Department of Pathology, Shimane Medical University, Izumo, Japan.
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Yamori
D000818:Animals; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000517:prevention & control*; D002561:Cerebrovascular Disorders / Q000209:etiology / Q000517:prevention & control; D003430:Cross-Sectional Studies; D004032:Diet; D004195:Disease Models, Animal; D006973:Hypertension / Q000209:etiology / Q000517:prevention & control*; D051381:Rats