[Interleukin-1 production in patients with unilocular echinococcosis].
The production of interleukin-1 (IL-1) by peripheral blood monocytes was estimated by the H. R. Recalde method (1984) in 45 patients with echinococcosis and 10 virtually healthy controls. In echinococcosis patients interleukin-1 turned to be significantly lower (p less than 0.05) than in the controls (Kact 1.2 +/- 0.1 and 2.2 +/- 0.1 respectively). In patients with a malignant course of the disease (mostly in those with disseminated lung damages) Kact of Il-1 was 0.93 +/- 0.1. In patients who underwent surgical interventions 1.5-6 years before Kact of Il-1 reached 1.43 +/- 0.1 but was still lower (p less than 0.05) than in the controls. The lowest production of IL-1 was identified in patients with lung disseminated lesions and bone damages (Kact 0.9 +/- 0.1 and 0.79 +/- 0.1, respectively).
Martsiniuk
A Iu
AIu
Ozeretskovskaia
N N
NN
Lur'e
A A
AA
Ul'ianov
A V
AV
D002478:Cells, Cultured / Q000276:immunology; D004443:Echinococcosis / Q000276:immunology*; D006801:Humans; D007158:Immunologic Techniques; D007375:Interleukin-1 / Q000096:biosynthesis* / Q000097:blood / Q000172:deficiency; D009000:Monocytes / Q000276:immunology
D007375:Interleukin-1
Produktsiia interleĭkina-1 u bol'nykh odnokamernym ékhinokokkozom.