[Fulminating cryptococcal meningoencephalitis. An anatomo-clinical case].
We report a case of cryptococcal meningoencephalitis in a 52 year-old man. The patient had complained of headache and drowsiness for a few hours before he became comatose with a bilateral sixth cranial nerve palsy. The cerebrospinal fluid contained less than one lymphocyte per cubic millimeter, a low glucose level (0.20 g/l) and numerous Cryptococcus neoformans encapsulated yeasts. A neuropathological study showed that the cortex and midbrain were involved. To our knowledge, such an acute case with death within the first 20 hours has not yet been reported.
Vermersch
P
P
Service de neurologie, Centre Hospitalier Universitaire, Lille.
Leys
D
D
Lorthioir
M
M
Pasquier
F
F
Krivosic
I
I
Petit
H
H
D001921:Brain / Q000473:pathology; D003453:Cryptococcosis / Q000134:cerebrospinal fluid / Q000473:pathology*; D006801:Humans; D008297:Male; D008590:Meningoencephalitis / Q000134:cerebrospinal fluid / Q000473:pathology*; D008875:Middle Aged; D013997:Time Factors
Cryptococcose neuro-méningée foudroyante. Un cas anatomo-clinique.