[Drug therapy of progressive myopia].
To stabilize weak and medium-severity progressive myopia, instillations of cycloplegics (homatropin or tropicamid) and of hypotensive agents (clofelin or thymolol) were administered into the conjunctival cavity once a day (at bedtime). The course of treatment lasted 30 days and was repeated every 2-3 months. Complete stabilization of myopia was achieved in 65-58% of cases, as evidenced by a follow-up of 3 years, on an average. Incomplete stabilization of the condition was observed in 35-42% of patients, the annual progress gradient being above 0.15 diopters. Simultaneously an accumulation of the relative accommodation reserves was observed, by 38.3% on an average, and a resolution of asthenopia. In a reference group of 50 subjects (100 eyes) spontaneous stabilization took place in 27% of cases, the relative accommodation reserve being unchanged.
A P
AP
Nesterov
A V
AV
Svirin
V I
VI
Lapochkin
D000293:Adolescent; D000328:Adult; D002986:Clinical Trials as Topic; D003228:Conjunctiva / Q000187:drug effects; D004359:Drug Therapy, Combination; D006801:Humans; D007322:Instillation, Drug; D009216:Myopia / Q000188:drug therapy* / Q000503:physiopathology; D009883:Ophthalmic Solutions; D010276:Parasympatholytics / Q000008:administration & dosage; D011725:Pyridines / Q000008:administration & dosage*; D013999:Timolol / Q000008:administration & dosage*; D014326:Tropanes / Q000008:administration & dosage*; D014331:Tropicamide / Q000008:administration & dosage*; D014792:Visual Acuity / Q000187:drug effects / Q000502:physiology
D009883:Ophthalmic Solutions; D010276:Parasympatholytics; D011725:Pyridines; D014326:Tropanes; D013999:Timolol; C100236:homatropine; D014331:Tropicamide
O medikamentoznom lechenii progressiruiushcheĭ blizorukosti.