Kikuchi's histiocytic necrotizing lymphadenitis.
Histiocytic necrotizing lymphadenitis (HNL) or Kikuchi's Disease is a peculiar condition most commonly affecting cervical lymph nodes in young women. Histology and immunohistochemistry demonstrate a florid T-cell and histiocytic reaction associated with necrotic areas which must be carefully distinguished from malignant lymphoma. Usually, the disease resolves spontaneously within a few weeks or months. The etiology is unknown and the physiopathology discussed.
Laboratoire d'Anatomie Pathologique, Hôpital Saint-Louis, Paris, France.
M F
MF
d'Agay
D
D
Ter-Mimasian
J
J
Trédaniel
E
E
Oksenhendler
C
C
Brocheriou
D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D008199:Lymphadenitis / Q000473:pathology* / Q000503:physiopathology; D008223:Lymphoma / Q000175:diagnosis; D009336:Necrosis