Efficacy of ceftizoxime in the treatment of uncomplicated gonorrhoea: comparison with amoxycillin.
Four centres contributed a total of 466 patients to a study comparing the efficacy of oral amoxycillin with that of probenecid and intramuscular ceftizoxime. Both treatments were equally efficacious, except in the small number of penicillinase-producing Neisseria gonorrhoeae patients, all of whom responded to ceftizoxime and none to amoxycyllin. Both treatments were well tolerated, the only two adverse effects occurring in the ceftizoxime group.
Warrington District Hospital, Cheshire.
M
M
Veeravahu
J C
JC
Clay
K C
KC
Mohanty
S J
SJ
Tovey
T M
TM
Wanas
K N
KN
Roberts
D000293:Adolescent; D000328:Adult; D000658:Amoxicillin / Q000627:therapeutic use*; D015296:Ceftizoxime / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011339:Probenecid / Q000627:therapeutic use
D000658:Amoxicillin; D015296:Ceftizoxime; D011339:Probenecid