[Proteolytic degradation of nuclear matrix proteins in the rat liver, Zajdela's hepatoma and hepatoma 22A in the presence of ATP].
An intense proteolytic degradation of both proteins and phosphoproteins has been observed in isolated nuclear matrices from rat liver, Zajdela Hepatoma and Hepatoma 22a, incubated with NP-40, DTT and gamma-[32P] ATP being most intense in Hepatoma 22a. Practically all phosphoproteins of Hepatoma 22a nuclear matrix degraded. This implies either an extremely high proteolytic activity in the preparation or the presence of a specific to phosphoproteins protease absent from rat liver and Zajdela Hepatoma nuclear matrices.
Mal'dov
D G
DG
Peskin
A V
AV
Zbarskiĭ
I B
IB
D000255:Adenosine Triphosphate / Q000494:pharmacology; D000818:Animals; D001345:Autoradiography; D004586:Electrophoresis; D066298:In Vitro Techniques; D008099:Liver / Q000201:enzymology*; D008114:Liver Neoplasms, Experimental / Q000201:enzymology*; D051379:Mice; D008809:Mice, Inbred C3H; D015530:Nuclear Matrix / Q000201:enzymology*; D009687:Nuclear Proteins / Q000378:metabolism*; D010447:Peptide Hydrolases / Q000378:metabolism*; D010750:Phosphoproteins / Q000378:metabolism*; D051381:Rats
D009687:Nuclear Proteins; D010750:Phosphoproteins; D000255:Adenosine Triphosphate; D010447:Peptide Hydrolases
Proteoliticheskiĭ raspad belkov iadernogo matriksa pecheni krysy, gepatomy Zaĭdela i gepatomy 22A v prisutstvii ATF.