A novel mycolic acid in a Mycobacterium sp. from the environment.
A fast-growing, non-photochromogenic mycobacterium isolated from the environment exhibited, on thin-layer chromatograms, a characteristic pattern of mycolates composed of unsaturated mycolates and also an unknown more polar component. Spectroscopic analysis and chemical degradation showed that this latter component was a novel mycolic acid containing a methoxy group at the omega-1 position (instead of omega-17 and omega-18 in known methoxymycolates), and two double bonds in the long mero aldehyde chain (instead of one as in known mycolates with additional oxygenated groups).
Luquin
M
M
Departamento de Microbiologia, Hospital de la Santa Cruz y San Pablo, Facultad de Medicina, Universidad Autónoma de Barcelona, Spain.
Roussel
J
J
Lopez-Calahorra
F
F
Lanéelle
G
G
Ausina
V
V
Lanéelle
M A
MA
D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009161:Mycobacterium / Q000032:analysis*; D009171:Mycolic Acids / Q000032:analysis* / Q000737:chemistry; D014871:Water Microbiology
D009171:Mycolic Acids