[The immunologic situation of the placenta and its significance for disorders in early pregnancy].
Reference is made in numerous recent immunological studies to immunological mechanisms which were found to play a role in acceptance of pregnancy or habitual abortions. The most important theories likely to offer explanations for these phenomena are reviewed in some detail, including hormonal immunosuppression, immunologic-anatomic barrier at the placenta as well as blocking factors and anti-sperm antibodies. Molar pregnancy is associated with a particular immunological situation. None of the theories mentioned can be preferred, for the time being, to explain acceptance of normal pregnancy or the causes of recurrent spontaneous abortions.
Institut für Pathologische Anatomie, Bereichs Medizin Karl-Marx-Universität Leipzig, DDR.
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Horn
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Rosenkranz
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Bilek
D000026:Abortion, Habitual / Q000276:immunology*; D000906:Antibodies / Q000276:immunology; D001667:Binding, Competitive; D005260:Female; D006801:Humans; D007108:Immune Tolerance; D008297:Male; D010920:Placenta / Q000276:immunology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology*; D013094:Spermatozoa / Q000276:immunology
D000906:Antibodies
Zur immunologischen Situation an der Plazenta und zu ihrer Bedeutung für Störungen in der Frühschwangerschaft.