Maternal awareness and neonatal outcome after ketamine induction of anaesthesia for Caesarean section.
Ketamine was used as the sole anaesthetic during the induction-to-delivery interval in 20 full-term patients undergoing elective Caesarean section. The intravenous administration of ketamine 1.5 mg.kg-1 was followed by succinylcholine 1.5 mg.kg-1 and tracheal intubation. The mother's lungs were then ventilated using 100 per cent oxygen until the baby was delivered. Intraoperative maternal awareness was assessed by the isolated forearm technique. The Apgar scores of the newborn at one and five minutes, as well as their umbilical vein blood gases were also evaluated and correlated with the induction-to-delivery (I-D) and the uterine incision-to-delivery (U-D) intervals. In 13 patients (Group A) the I-D interval was less than 10 min and U-D interval less than 90 sec, while in seven (Group B) the I-D interval was greater than or equal to 10 min and the U-D interval greater than or equal to 90 sec. The isolated arm test was negative in all patients having an I-D interval less than 10 min, and was positive in three patients when the I-D interval exceeded ten minutes. The newborns of group A showed higher Apgar scores at one minute, as well as higher umbilical vein PO2 than was achieved in Group B. It was concluded that the technique used was not associated with maternal awareness or neonatal depression, provided that the I-D interval was less than 10 min and the U-D interval was less than 90 sec.
Department of Anesthesiology, American University of Beirut, Lebanon.
A
A
Baraka
F
F
Louis
R
R
Dalleh
D000328:Adult; D000768:Anesthesia, General; D000773:Anesthesia, Obstetrical; D001034:Apgar Score; D001364:Awareness / Q000187:drug effects*; D001784:Blood Gas Analysis; D001794:Blood Pressure / Q000187:drug effects; D002585:Cesarean Section / Q000379:methods; D036861:Delivery, Obstetric; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007231:Infant, Newborn; D007649:Ketamine / Q000494:pharmacology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D012119:Respiration / Q000187:drug effects; D013997:Time Factors; D014471:Umbilical Veins
D007649:Ketamine