[Use of New World Saimiri and Aotus monkeys in the development of an anti-malaria vaccine].
Saimiri and Aotus, two neotropical primates, are currently used in different domains of human malaria research. Here we present a simplified and non exhaustive enumeration of different aspects in concern of using these monkeys as experimental hosts, their availability, laboratory-bred animals versus wild-caught animals, their potential as experimental model in evaluating anti-malaria vaccine candidates, and some related activities at the Pasteur Institute.
Laboratoire d'Immunologie Parasitaire, Institut Pasteur de la Guyane Française, Cayenne.
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D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use*; D001029:Aotus trivirgatus / Q000276:immunology*; D002427:Cebidae / Q000276:immunology*; D004195:Disease Models, Animal; D007167:Immunotherapy / Q000379:methods; D008288:Malaria / Q000276:immunology / Q000517:prevention & control*; D012453:Saimiri / Q000276:immunology*; D014612:Vaccines
D000962:Antimalarials; D014612:Vaccines
L'utilisation des singes du nouveau monde Saimiri et Aotus dans le développement d'un vaccin anti-paludique.