Nucleotide sequence of SHV-2 beta-lactamase gene.
The nucleotide sequence of plasmid-mediated beta-lactamase SHV-2 from Salmonella typhimurium (SHV-2pHT1) was determined. The gene was very similar to chromosomally encoded beta-lactamase LEN-1 of Klebsiella pneumoniae. Compared with the sequence of the Escherichia coli SHV-2 enzyme (SHV-2E.coli) obtained by protein sequencing, the deduced amino acid sequence of SHV-2pHT1 differed by three amino acid substitutions.
Laboratoire de Microbiologie, Hopital Trousseau, Paris, France.
A
A
Garbarg-Chenon
V
V
Godard
R
R
Labia
J C
JC
Nicolas
D000595:Amino Acid Sequence; D001483:Base Sequence; D002876:Chromosomes, Bacterial; D008969:Molecular Sequence Data; D010957:Plasmids; D012486:Salmonella typhimurium / Q000235:genetics*; D013462:Sulfur Radioisotopes; D001618:beta-Lactamases / Q000235:genetics*
D013462:Sulfur Radioisotopes; D001618:beta-Lactamases