Serial imaging of Menkes disease.
The patient developed myoclonic seizures at 3 months of age and his hair demonstrated the pili torti pattern. The low serum copper content and ceruloplasmin confirmed the diagnosis of Menkes disease. The characteristic signs on the images were: high echo level regions in the cerebrum as detected by brain ultrasonography, low density areas of white matter detected by CT scan, and low signal intensities of white matter by both T1 and balanced MR images.
Department of Pediatrics, Jichi Medical School, Tochigi, Japan.
K
K
Ichihashi
S
S
Yano
S
S
Kobayashi
M
M
Miyao
M
M
Yanagisawa
D001921:Brain / Q000473:pathology*; D001928:Brain Diseases, Metabolic / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D008297:Male; D007706:Menkes Kinky Hair Syndrome / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography