Clinical efficacy of famotidine in the treatment of acid-related diseases: an overview.
The clinical efficacy of famotidine has been clearly shown in the short- and long-term treatment of a number of acid-related diseases such as duodenal and gastric ulcer as well as in the acute management of reflux esophagitis. In addition, famotidine effectively treats anastomotic ulcer and nonulcer dyspepsia. Based on a number of considerations--chemical structure, pharmacokinetics, pharmacodynamics, clinical efficacy, tolerability, and dosage regimen--famotidine represents an end-point in the development of the H2-antagonist group of anti-ulcer agents.
Dammann
H G
HG
Department of Gastroenterology, Bethanien Hospital, Hamburg, West Germany.
D002986:Clinical Trials as Topic; D004381:Duodenal Ulcer / Q000188:drug therapy*; D004942:Esophagitis, Peptic / Q000188:drug therapy*; D015738:Famotidine / Q000627:therapeutic use*; D006801:Humans; D011358:Product Surveillance, Postmarketing; D013276:Stomach Ulcer / Q000188:drug therapy*
D015738:Famotidine