[An animal experiment study using the Gore-Tex soft tissue patch as a replacement for lyophilized dura mater].
Fractures of the skull base are often accompanied by dural lesions. Lyophilized dura mater is very valuable for dural reconstruction at the level of the smooth convex posterior wall of the frontal sinus, but surgery in the region of the uneven ethmoidal roof and lateral to the falx cerebri is difficult. The Gore-Tex patch is very soft and comfortable: vascular prostheses manufactured from this material have been implanted successfully for years. This material was subjected to a check of histocompatibility as a replacement for lyophilized dura in animal experiments by intracranial implantation. Lyodura is replaced by collagenous tissue, whereas Gore-Tex is incorporated by fibroblastic and osteoblastic penetration. This alloplastic material is an alternative tissue to lyophilized dura but should be reserved for special situations.
HNO-Klinik, Klinikum Mannheim.
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Schadel
D000818:Animals; D001672:Biocompatible Materials; D003094:Collagen / Q000378:metabolism; D003238:Connective Tissue / Q000473:pathology; D004388:Dura Mater / Q000601:surgery*; D005549:Foreign-Body Reaction / Q000473:pathology*; D006097:Granulation Tissue / Q000473:pathology; D011138:Polytetrafluoroethylene; D011817:Rabbits; D012886:Skull / Q000601:surgery*; D014945:Wound Healing / Q000502:physiology
D001672:Biocompatible Materials; C032281:Lyodura; D011138:Polytetrafluoroethylene; D003094:Collagen
Tierexperimentelle Studie über den Gore-Tex Soft Tissue Patch als Ersatz für die lyophilisierte Dura mater.