Oral complications of cancer therapies. Oral complications in the pediatric population.
A number of acute oral complications may be associated with cancer therapy in children, but the extent and duration of these complications, and the most effective management techniques. have not been well described. The few studies differ in design, making comparisons difficult. Well-controlled, prospective clinical studies are needed to define the most effective strategies for the management of acute oral complications in children. However, it is clear that dental intervention prior to cancer therapy is an important factor in the optimal preparation of the patient. During cancer therapy, intensive supervised oral preventive protocols appear to be of benefit to the child's oral health, overall comfort, and well-being. Furthermore, the prevention of oral infection may significantly reduce the morbidity associated with cancer therapy. Long-term preventive oral care may help prevent dental disease and infection in medically compromised children and contribute to improving the quality of life.
Leggott
P J
PJ
Oral AIDS Center, University of California, San Francisco.
D000970:Antineoplastic Agents / Q000009:adverse effects*; D006801:Humans; D007239:Infections / Q000209:etiology; D009059:Mouth Diseases / Q000209:etiology* / Q000517:prevention & control; D009061:Mouth Mucosa / Q000187:drug effects / Q000528:radiation effects; D009369:Neoplasms / Q000628:therapy*; D011878:Radiotherapy / Q000009:adverse effects*
D000970:Antineoplastic Agents