[The study of protein-peptide hormones using genetic engineering methods (review of the literature)].
Use of genetic engineering technique in cloning and sequence assay of cDNA and genes coding for mammal protein and peptide hormones is reviewed. Recent data on molecular aspects of gene reorganization in some inherited disorders are considered involving analytical methods for evaluation of gene activity, especially of genes coding for peptide hormones. Sequence assay of mRNA coding for mammal proopiomelanocortins (precursor of adrenocorticotropic hormone), beta-lipotropic hormones of pituitary body, is discussed.
N P
NP
Mertvetsov
V A
VA
Karginov
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D006728:Hormones / Q000096:biosynthesis* / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D010452:Peptide Biosynthesis; D010455:Peptides / Q000235:genetics; D014176:Protein Biosynthesis; D015202:Protein Engineering; D011506:Proteins / Q000235:genetics
D006728:Hormones; D010455:Peptides; D011506:Proteins
Issledovanie belkovo-peptidnykh gormonov metodami geneticheskoĭ inzhenerii (obzor).