[Genetic complementation in the study of mechanisms of inborn errors of metabolism in man (review of the literature)].
Application of genetic complementation procedure for evaluation of heterogeneity and development of a number of human inherited impairments, particularly, lysosomal storage diseases, are reviewed. The genetic complementation procedure is involved in cytobiochemical diagnosis of a number of enzymopathies as well as in studies of subunit containing enzymes reconstruction and their function.
Baskaeva
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EM
D000818:Animals; D005816:Genetic Complementation Test; D006801:Humans; D006822:Hybrid Cells; D008661:Metabolism, Inborn Errors / Q000175:diagnosis / Q000235:genetics*; D012497:Sandhoff Disease / Q000175:diagnosis / Q000235:genetics; D013661:Tay-Sachs Disease / Q000175:diagnosis / Q000235:genetics
Geneticheskaia komplementatsiia v izuchenii mekhanizmov razvitiia nasledstvennykh narusheniĭ obmena veshchestv u cheloveka (obzor).