Medication-induced esophagitis in children.
Clinical and endoscopic features of two pediatric cases of esophageal ulcers caused by capsules of oxytetracycline and doxycycline are described. Several cases of medication-induced esophageal injury in children have been reported until now, all of which were in association with tablets or capsules. Antibiotics are known to be responsible for medication-induced esophagitis in adults. In this study, 4 cases were caused by emepronium bromide and 3 cases, including the present patients, by antibiotics. All cases but one complained of chest pain and/or dysphagia. Although the interval between the onset of the symptoms and the diagnosis varied among cases, the clinical courses were relatively uneventful, without any long-term sequelae. This clinical entity seems to be unfamiliar to pediatricians and is omitted from the differential diagnosis.
Department of Pediatrics, Sendai City Hospital, Japan.
S
S
Kato
K
K
Komatsu
Y
Y
Harada
D002648:Child; D004318:Doxycycline / Q000009:adverse effects* / Q000627:therapeutic use; D004941:Esophagitis / Q000139:chemically induced*; D006801:Humans; D008297:Male; D010118:Oxytetracycline / Q000009:adverse effects* / Q000627:therapeutic use; D014456:Ulcer / Q000139:chemically induced
D004318:Doxycycline; D010118:Oxytetracycline