[Delimiting the molecular envelope of a protein by deconvolution of the Patterson function for native proteins].
A process, based on the superposition method, is described to delimit the molecular envelope of a protein by deconvolution of the Patterson function. The object is to obtain a preliminary set of phases from native structure-factor amplitudes with only native intensity data. The method has been tested with data from two immunoglobulin Fab fragments, Fab NEW and Fab R19.9. Several zones of resolution were explored.
Unité d'Immunologie Structurale, Institut Pasteur, Paris, Cedex, France.
G S
GS
Chiglien
D007128:Immunoglobulin Fragments; D008432:Mathematical Computing; D011487:Protein Conformation; D014961:X-Ray Diffraction / Q000379:methods*
D007128:Immunoglobulin Fragments
Obtention de l'enveloppe moléculaire des protéines par la déconvolution de la fonction de Patterson de ces protéines natives.