[Evaluation of the efficacy of amino 4-quinolones in a chemoresistant zone. Proposals for new therapeutic schemes].
The authors compare the respective therapeutic efficiency of chloroquine and amodiaquine in the treatment of Plasmodium falciparum malaria fever in urban dispensaries. Chloroquine has a constant rate of efficiency, whatever dosage and duration of treatment be and should be saved for home presumptive treatment of malaria fever. Amodiaquine at a dose of 35 mg/kg in 3 days leads to a noticeable clinical success (96.5 p.c.). It should be selected as drug of first to treat any malaria fever case biologically confirmed, in urban dispensaries.
Biologiste des Hôpitaux, Organisation de Coordination pour la lutte contre les Grandes Endémies en Afrique Centrale (O.C.E.A.C.), Yaoundé, Cameroun.
C
C
Hengy
P
P
Gazin
F
F
Eberle
R
R
Jambou
J P
JP
Louis
D000655:Amodiaquine / Q000008:administration & dosage / Q000627:therapeutic use*; D000818:Animals; D002163:Cameroon; D002738:Chloroquine / Q000008:administration & dosage / Q000627:therapeutic use*; D002985:Clinical Protocols / Q000592:standards*; D004351:Drug Resistance; D006801:Humans; D008288:Malaria / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy*; D010594:Pharmacies; D010963:Plasmodium falciparum; D014505:Urban Population
D000655:Amodiaquine; D002738:Chloroquine
Evaluation de l'efficacité des amino-4 quinoléines en zone de chimioresistance: proposition de nouveaux schémas thérapeutiques.