[The future of vaccines: recombinant DNA vaccines].
Classical approaches to the development of vaccines have provided mankind with a number of safe and effective vaccines (think of the world-wide eradication of smallpox). Nevertheless, some obstacles e.g. the production of a safe Hepatitis B vaccine, could not be taken by classical techniques. In several cases, recombinant-DNA technology provided an elegant solution, though in other cases, this technique also failed. The present paper presents a brief review of the role of recombinant-DNA technology in the current development of vaccines.
van Dam
R H
RH
Duphar B.V., Animal Health Division, Weesp.
Keus
R J
RJ
D000276:Adjuvants, Immunologic; D000818:Animals; D004274:DNA, Recombinant; D014611:Vaccination / Q000662:veterinary*; D014612:Vaccines / Q000302:isolation & purification*; D014613:Vaccines, Attenuated / Q000008:administration & dosage / Q000302:isolation & purification*; D015164:Vaccines, Inactivated / Q000302:isolation & purification; D014614:Vaccines, Synthetic / Q000302:isolation & purification
D000276:Adjuvants, Immunologic; D004274:DNA, Recombinant; D014612:Vaccines; D014613:Vaccines, Attenuated; D015164:Vaccines, Inactivated; D014614:Vaccines, Synthetic
De toekomst van vaccins: recombinant-DNA vaccins.