Contact allergy due to colophony (VI). The sensitizing capacity of minor resin acids and 7 commercial modified-colophony products.
3 minor resin acids and 7 commercial modified-colophony products of different origins were studied by experimental sensitization by means of a modified FCA method. All 3 resin acids were almost negative. The commercial products gave different results. While the maleic-modified product of Greek origin showed a strong sensitizing power, the fumaric-modified, terpene-phenol-modified and a disproportioned rosin were only moderate. A remarkable difference was obtained with the Swedish and Finnish tall oil rosins, which, in contrast to the previously studied French product, exhibited only a weak sensitizing capacity.
Department of Dermatology, University Hospital, Hamburg, FRG.
B M
BM
Hausen
C
C
Hessling
D000818:Animals; D003429:Cross Reactions / Q000276:immunology; D003877:Dermatitis, Contact / Q000276:immunology*; D005260:Female; D005620:Freund's Adjuvant / Q000008:administration & dosage; D006168:Guinea Pigs; D007271:Injections, Intradermal; D010938:Plant Oils; D012116:Resins, Plant / Q000008:administration & dosage / Q000009:adverse effects*; D013638:Tars / Q000008:administration & dosage / Q000009:adverse effects*
D010938:Plant Oils; D012116:Resins, Plant; D013638:Tars; C482568:tall oil; C013893:rosin; D005620:Freund's Adjuvant