[Lymphocyte-mediated immunological tests].
Two major types of immune response are present in the body; specific humoral antibody response and specific cell-mediated immune response. Lymphocytes play the major role in cell-mediated immune response, and also control the humoral antibody response. Lymphocyte functions are measured by various laboratory tests, including (1) peripheral lymphocyte count and morphology, (2) lymphocyte surface markers, (3) lymphocyte function tests with lymphocyte culture, (4) histopathological findings of the immune organs such as thymus, lymph nodes, intestinal lymphoid tissue and palatine tonsils. In routine practice, peripheral lymphocyte count and morphology is most commonly used, and then lymphocyte surface markers are measured by flow cytofluorometry using various monoclonal antibodies.
Department of Clinical Pathology, Jichi Medical School, Tochigi.
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Kawai
D000954:Antigens, Surface / Q000032:analysis; D005434:Flow Cytometry; D006801:Humans; D007159:Immunologic Tests / Q000379:methods; D007958:Leukocyte Count; D008214:Lymphocytes / Q000166:cytology / Q000276:immunology*
D000954:Antigens, Surface