Ophthalmic neoplasms in infancy and childhood.
The most common ocular and orbital tumors presenting in infancy, childhood and adolescence are presented and discussed in this review. It has been prepared specifically for the clinical pediatrician and focuses on the clinical recognition of ophthalmic neoplasms, their diagnostic evaluation employing the use of advanced imaging techniques, biopsy when indicated and extent of disease workup. In addition, current treatment modalities are discussed. Ocular tumors addressed include: retinoblastoma, capillary hemangioma, lymphangioma, dermoid and epidermoid cysts, teratoma, glioma, astrocytic hamartoma, neurofibroma, rhabdomyosarcoma and fibrous tumors. Two aggressive and potentially fatal tumors, rhabdomyosarcoma and retinoblastoma, are presented in detail. In addition, the ocular tumors associated with the phakomatoses (von Hippel-Lindau, tuberous sclerosis and neurofibromatosis) are reviewed.
Department of Pediatrics, New York Hospital/Cornell University Medical Center, New York.
K W
KW
Sykora
R A
RA
Weiss
R M
RM
Ellsworth
B
B
McCormick
D000293:Adolescent; D002648:Child; D003389:Cranial Nerve Diseases; D003390:Cranial Nerve Neoplasms; D005134:Eye Neoplasms; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D009900:Optic Nerve; D009918:Orbital Neoplasms