Evaluation of the EZ-SCREEN enzyme immunoassay test for detection of cocaine and marijuana metabolites in urine specimens.
The EZ-SCREEN Cannabinoid/Cocaine test is a qualitative enzyme immunoassay card test for the detection of cannabinoid and cocaine metabolites in urine specimens. Results are available in about three minutes. The test kit costs approximately $12.00 per two-drug test, and there are no additional expenses for analytical equipment. We compared the results of the EZ-SCREEN test with results of specimens analyzed by gas chromatography/mass spectrometry (GC/MS) for 36 clinical specimens positive for cannabinoids (marijuana), 38 clinical specimens positive for benzoylecgonine (cocaine), and 33 drug-free specimens. Results from our study for marijuana included: sensitivity = 92%; specificity = 89%; and efficiency = 95, 67, and 87%, respectively. In the present study, there were five false-positive tests for cocaine and one false-positive test for cannabinoids. As with all screening test results, confirmation of positive specimens by a more specific quantitative analytical method such as GC/MS is recommended.
Department of Pediatrics, Fairfax Hospital, Falls Church, Virginia.
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Schwartz
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Bogema
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Thorne
D002186:Cannabinoids / Q000652:urine*; D003042:Cocaine / Q000652:urine*; D005069:Evaluation Studies as Topic; D006801:Humans; D007124:Immunoenzyme Techniques; D015813:Substance Abuse Detection / Q000295:instrumentation / Q000379:methods*
D002186:Cannabinoids; D003042:Cocaine