Chromosomal reallocation of the chicken c-myb locus and organization of 3'-proximal coding exons.
In the course of our studies concerning the tissue-specific expression of the c-myb proto-oncogene, we have established the nucleotide sequence of the chicken c-myb 3'-proximal coding exons. In situ hybridization performed with different genomic DNA probes corresponding to nearly all the c-myb gene allowed us to localize the corresponding locus on the large acrocentric chromosome 3 in chicken. Our sequencing data also indicate that the 3'-proximal noncoding sequences represented in c-myb mRNA species are derived from non-contiguous exons.
Soret
J
J
Laboratoire d'Oncologie Virale et Moléculaire, Centre Universitaire, Orsay, France.
Vellard
M
M
Viegas-Pequignot
E
E
Apiou
F
F
Dutrillaux
B
B
Perbal
B
B
D000818:Animals; D001483:Base Sequence; D015139:Blotting, Southern; D002645:Chickens / Q000235:genetics*; D002874:Chromosome Mapping; D004247:DNA / Q000235:genetics*; D015342:DNA Probes; D005091:Exons; D008969:Molecular Sequence Data; D009693:Nucleic Acid Hybridization; D011518:Proto-Oncogene Proteins / Q000235:genetics*; D020598:Proto-Oncogene Proteins c-myb
D015342:DNA Probes; D011518:Proto-Oncogene Proteins; D020598:Proto-Oncogene Proteins c-myb; D004247:DNA