Acetylcholine translocating protein: mediatophore at rat neuromuscular synapses.
The neuromuscular synapses of the rat sternomastoid muscles contain a membrane protein, mediatophore, that endows artificial membranes with a calcium-dependent acetylcholine release mechanism. Mediatophore and choline acetylase had similar distributions along the muscle. Sciatic nerve membranes contain mediatophore, and a purified preparation was obtained from the nerve.
Département de Neurochimie, CNRS, Gif-sur-Yvette, France.
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Israël
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Lesbats
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Sbia
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Morel
D000109:Acetylcholine / Q000235:genetics*; D000818:Animals; D001381:Azepines / Q000494:pharmacology; D008297:Male; D009419:Nerve Tissue Proteins / Q000037:antagonists & inhibitors / Q000378:metabolism* / Q000502:physiology; D009469:Neuromuscular Junction / Q000378:metabolism*; D051381:Rats / Q000378:metabolism*; D011919:Rats, Inbred Strains; D012584:Sciatic Nerve / Q000378:metabolism; D013569:Synapses / Q000378:metabolism*; D014101:Torpedo / Q000378:metabolism
D001381:Azepines; D009419:Nerve Tissue Proteins; C050299:mediatophore; C006955:cetiedil; D000109:Acetylcholine