Early information processing in schizophrenia.
In summary, approaches from various sensory modalities indicate a similar processing deficit for various schizophrenics occurring at approximately 100 milliseconds during or post-stimulus presentation. This deficit occurs during the time period that has been associated with a dysfunctional inhibitory mechanism that is maximally activated during the 100 millisecond time period (e.g., during the period of temporal integration). The inhibitory mechanism is presently conceptualized as being a "transient" or "fast" system involved in the serial/sequential processing of information. The inability of certain schizophrenics to serially process may suggest a dysfunctional inhibitory mechanism for which GABA is a potential candidate.
Tulane University Medical Center, New Orleans, Louisiana.
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BD
Schwartz
D001143:Arousal / Q000502:physiology; D001288:Attention / Q000502:physiology; D006801:Humans; D019965:Neurocognitive Disorders / Q000175:diagnosis*; D011603:Psychophysiology; D012438:Saccades / Q000502:physiology; D012559:Schizophrenia / Q000175:diagnosis*; D012565:Schizophrenic Psychology