A novel mycolic acid in a Mycobacterium sp. from the environment.
A fast-growing, non-photochromogenic mycobacterium isolated from the environment exhibited, on thin-layer chromatograms, a characteristic pattern of mycolates composed of unsaturated mycolates and also an unknown more polar component. Spectroscopic analysis and chemical degradation showed that this latter component was a novel mycolic acid containing a methoxy group at the omega-1 position (instead of omega-17 and omega-18 in known methoxymycolates), and two double bonds in the long mero aldehyde chain (instead of one as in known mycolates with additional oxygenated groups).
Departamento de Microbiologia, Hospital de la Santa Cruz y San Pablo, Facultad de Medicina, Universidad Autónoma de Barcelona, Spain.
M
M
Luquin
J
J
Roussel
F
F
Lopez-Calahorra
G
G
Lanéelle
V
V
Ausina
M A
MA
Lanéelle
D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D009161:Mycobacterium / Q000032:analysis*; D009171:Mycolic Acids / Q000032:analysis* / Q000737:chemistry; D014871:Water Microbiology
D009171:Mycolic Acids