Frequency of the major CF mutation in French CF patients.
We have studied 124 patients of French origin, whose CF status had already been clearly established. These children belong to families previously tested with restriction fragment length polymorphism (RFLP) markers in our laboratory for genetic counselling. The most common mutation (delta F508) accounts for 67% in this population sample.
Institut de Pathologie Moléculaire, CHU Cochin, Paris, France.
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Chomel
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Haliassos
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Tesson
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Kaplan
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Kitzis
D002872:Chromosome Deletion; D003550:Cystic Fibrosis / Q000453:epidemiology / Q000235:genetics*; D005602:France / Q000453:epidemiology; D005787:Gene Frequency; D006801:Humans