Humoral immune response to the bovine immunodeficiency-like virus in experimentally and naturally infected cattle.
Calves inoculated with bovine immunodeficiency-like virus (BIV) produced virus-specific antibodies that could be detected from 2 weeks to 2.5 years postinoculation by using both indirect fluorescent-antibody and Western immunoblot assays. Antibodies were primarily to p26. Virus and BIV-specific antibodies were isolated from calves given BIV-infected blood. Antibodies to BIV proteins were found in sera from naturally infected cattle.
U.S. Department of Agriculture, National Animal Disease Center, Ames, Iowa 50010.
C A
CA
Whetstone
M J
MJ
VanDerMaaten
J W
JW
Black
D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D015153:Blotting, Western; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology* / Q000382:microbiology / Q000635:transmission; D005455:Fluorescent Antibody Technique; D007153:Immunologic Deficiency Syndromes / Q000276:immunology / Q000662:veterinary*; D008970:Molecular Weight; D012190:Retroviridae / Q000276:immunology*
D000914:Antibodies, Viral