The genetics of human alcohol metabolism.
1. The custom of drinking alcoholic beverages is a human behavior with serious social and medical consequences for a surprisingly large fraction of drinkers. 2. This review describes recent advances in our understanding of the genetic loci that control enzyme systems involved in the metabolism of alcohol. 3. These advances make possible new experimental programs that may lead to simple diagnostic tests for patients at risk of developing alcohol abuse behaviour.
School of Biological Sciences, Victoria University, Wellington, New Zealand.
G K
GK
Chambers
D000426:Alcohol Dehydrogenase / Q000235:genetics; D000428:Alcohol Drinking; D000444:Aldehyde Dehydrogenase / Q000235:genetics; D000818:Animals; D000431:Ethanol / Q000378:metabolism*; D006801:Humans; D008967:Molecular Biology
D000431:Ethanol; D000426:Alcohol Dehydrogenase; D000444:Aldehyde Dehydrogenase