An epidemiologic survey of cardiovascular disease in women taking oral contraceptives.
Earlier epidemiologic studies have indicated an increase in mortality from certain cardiovascular diseases in young women associated with the use of oral contraceptives. However, since these studies were conducted, newer oral contraceptives containing less estrogen and progestogen have been widely adopted. In addition, an increasing majority of oral contraceptive use is by women under the age of 30 years. Early results from a new case-control study suggest the possibility that the risk of myocardial infarction associated with oral contraceptive use is now lower than in the past, although the previously observed small increase in the risk of subarachnoid hemorrhage appears to be unchanged.
Department of Community Medicine and General Practice, University of Oxford, England.
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Thorogood
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Vessey
D000293:Adolescent; D000328:Adult; D002318:Cardiovascular Diseases / Q000139:chemically induced / Q000453:epidemiology*; D016022:Case-Control Studies; D015331:Cohort Studies; D003278:Contraceptives, Oral, Hormonal / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D006113:United Kingdom / Q000453:epidemiology
D003278:Contraceptives, Oral, Hormonal