Hypocalcemic hyper-CK-emia in hypoparathyroidism.
A 15-year-old boy with increased serum creatine kinase (hyper-CK-emia) due to hypocalcemia in turn caused by idiopathic hypoparathyroidism (HP) is presented. Hyper-CK-emia was incidentally noted while managing a patient, aged nine, with mental retardation, epilepsy and mild hypocalcemia. Neurological examination showed normal deep tendon reflexes and no muscle weakness; electromyogram was normal. The hyper-CK-emia normalized during treatment for the hypocalcemia. Previously reported patients with hypocalcemic hyper-CK-emia or myopathy together with HP are discussed, as well as the degree of hypocalcemia and the wide spectrum of the muscle dysfunction.
Department of Pediatrics, Nagoya City University Medical School, Japan.
T
T
Ishikawa
H
H
Inagaki
M
M
Kanayama
T
T
Manzai
D000293:Adolescent; D003402:Creatine Kinase / Q000097:blood*; D006801:Humans; D006996:Hypocalcemia / Q000201:enzymology* / Q000209:etiology; D007011:Hypoparathyroidism / Q000150:complications*; D008297:Male; D009135:Muscular Diseases / Q000201:enzymology / Q000209:etiology*
D003402:Creatine Kinase