Hypocalcemic hyper-CK-emia in hypoparathyroidism.
A 15-year-old boy with increased serum creatine kinase (hyper-CK-emia) due to hypocalcemia in turn caused by idiopathic hypoparathyroidism (HP) is presented. Hyper-CK-emia was incidentally noted while managing a patient, aged nine, with mental retardation, epilepsy and mild hypocalcemia. Neurological examination showed normal deep tendon reflexes and no muscle weakness; electromyogram was normal. The hyper-CK-emia normalized during treatment for the hypocalcemia. Previously reported patients with hypocalcemic hyper-CK-emia or myopathy together with HP are discussed, as well as the degree of hypocalcemia and the wide spectrum of the muscle dysfunction.
Ishikawa
T
T
Department of Pediatrics, Nagoya City University Medical School, Japan.
Inagaki
H
H
Kanayama
M
M
Manzai
T
T
D000293:Adolescent; D003402:Creatine Kinase / Q000097:blood*; D006801:Humans; D006996:Hypocalcemia / Q000201:enzymology* / Q000209:etiology; D007011:Hypoparathyroidism / Q000150:complications*; D008297:Male; D009135:Muscular Diseases / Q000201:enzymology / Q000209:etiology*
D003402:Creatine Kinase