[A clinical study of cyclopyroxolamine versus clotrimazole in the treatment of mycotic vulvovaginitis].
The therapeutic efficacy and tolerability of the antifungal agent ciclopiroxolamine have been verified with a double-blind study versus clotrimazole in 46 patients affected by vulvovaginal candidiasis. The patients of the first group (23) have been treated with ciclopiroxolamine globules, one 100 mg globule nightly for six days; the second group (23 patients) received clotrimazole vaginal tablets, one 200 mg tablet nightly for six days. Ciclopiroxolamine treatment showed an equivalent effectiveness to that of clotrimazole both on signs and symptoms and on vaginal smear culture. No local or systemic adverse reaction was observed.
Consultorio Familiare U.S.L. n. 8, Genova Ponente.
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Giannoni
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Pollastro
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Jacobellis
D000282:Administration, Intravaginal; D000293:Adolescent; D000328:Adult; D000368:Aged; D000935:Antifungal Agents / Q000009:adverse effects / Q000627:therapeutic use*; D002181:Candidiasis, Vulvovaginal / Q000188:drug therapy*; D000077768:Ciclopirox; D003022:Clotrimazole / Q000009:adverse effects / Q000627:therapeutic use*; D004311:Double-Blind Method; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D007093:Imidazoles / Q000627:therapeutic use*; D008875:Middle Aged; D011728:Pyridones / Q000009:adverse effects / Q000627:therapeutic use*; D016032:Randomized Controlled Trials as Topic; D013607:Tablets
D000935:Antifungal Agents; D007093:Imidazoles; D011728:Pyridones; D013607:Tablets; D000077768:Ciclopirox; D003022:Clotrimazole
Studio clinico sulla ciclopiroxolamina versus clotrimazolo nel trattamento delle vulvovaginiti micotiche.