Oral ketamine premedication for paediatric cardiac surgery--a comparison with intramuscular morphine (both after oral trimeprazine).
In a single-blind controlled study, forty children with congenital heart disease were premedicated with oral trimeprazine 3 mg/kg and either intramuscular morphine 0.1 mg/kg or oral ketamine 10 mg/kg. Cardiovascular and respiratory effects of premedication and degree of sedation induced were similar in the two groups of patients. Oral ketamine is a safe and effective premedicant in this group of patients.
Department of Anaesthetics, Grantham Hospital, Hong Kong.
K G
KG
Stewart
S J
SJ
Rowbottom
A W
AW
Aitken
S
S
Rajendram
D A
DA
Sudhaman
D000284:Administration, Oral; D006348:Cardiac Surgical Procedures; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007273:Injections, Intramuscular; D007649:Ketamine / Q000008:administration & dosage*; D008297:Male; D009020:Morphine / Q000008:administration & dosage*; D011229:Preanesthetic Medication; D016032:Randomized Controlled Trials as Topic; D014291:Trimeprazine / Q000008:administration & dosage*
D007649:Ketamine; D014291:Trimeprazine; D009020:Morphine