Parkinsonism with neuroacanthocytosis.
Two patients with neuroacanthocytosis are described. One presented with parkinsonism and the other resembled diurnal dystonia of the Segawa type. Both patients responded well to dopaminomimetic therapy. A PET scan with fluorodopa revealed a nigrostriatal deficit in the first patient.
Department of Medicine, University of British Columbia, Vancouver, Canada.
R F
RF
Peppard
C S
CS
Lu
N S
NS
Chu
P
P
Teal
W R
WR
Martin
D B
DB
Calne
D000050:Acanthocytes / Q000648:ultrastructure*; D000328:Adult; D002230:Carbidopa / Q000627:therapeutic use; D004912:Erythrocytes / Q000648:ultrastructure; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000097:blood* / Q000150:complications / Q000000981:diagnostic imaging; D014055:Tomography, Emission-Computed
D008055:Lipids; D007980:Levodopa; D002230:Carbidopa