Mechanisms of stress ulceration and implications for treatment.
The incidence of stress ulceration and its complications has decreased over the last decade significantly. The reason for this development is the better understanding of the protective mechanism of stomach and duodenum as well as the prophylactic treatment. This can be achieved by antacids, H2-blockers, and sucralfate, whereas prostaglandins are not effective.
University of Vienna, University Clinic of Surgery, Austria.
R
R
Schiessel
W
W
Feil
E
E
Wenzl
D000863:Antacids / Q000627:therapeutic use; D002927:Cimetidine / Q000627:therapeutic use; D015232:Dinoprostone / Q000627:therapeutic use; D004381:Duodenal Ulcer / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D013276:Stomach Ulcer / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D013312:Stress, Physiological / Q000150:complications*
D000863:Antacids; D002927:Cimetidine; D015232:Dinoprostone