ESWL and gallstone dissolution with MTBE via a naso-vesicular catheter.
Endoscopic placement of a naso-vesicular catheter was successful in 90% (45/50) of patients with cholecystolithiasis. The first 7 patients were treated by MTBE dissolution alone. Dissolution was discontinued after a maximum of 14 days, as only two patients were rendered stone free. In one patient, 3 tiny pigment stones were sucked out through the catheter, and in another inoperable patient a pigtail endoprosthesis was finally inserted into the gallbladder. In the remaining 36 patients, combined ESWL and MTBE dissolution therapy was carried out. Treatment was broken off by one patient after one week, and interrupted in another due to catheter dislodgement. After an average of 10 days with 1-9 ESWL sessions (average: 3) complete stone clearance was achieved in 60% (20/34) of patients. Fourteen of the patients who completed treatment, and the one with catheter dislodgement still have sludge in the gallbladder, which is being treated with oral bile acids. The procedure-related complication rate was 10% (3 pancreatitis, 1 cystic duct perforation and 1 guidewire impaction). The mortality rate was zero. There was no evident complication due to either ESWL or MTBE dissolution.
Department of Endoscopic Surgery and General Surgery, University Hospital of Hamburg, Germany.
N
N
Soehendra
H
H
Schulz
V C
VC
Nam
A
A
Maydeo
J P
JP
Schenkengel
H
H
Grimm
M
M
Brueckner
B
B
Eckmann
H W
HW
Schreiber
D002404:Catheterization / Q000379:methods; D002769:Cholelithiasis / Q000628:therapy*; D003131:Combined Modality Therapy; D004987:Ethers / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008096:Lithotripsy; D008297:Male; D008738:Methyl Ethers; D008875:Middle Aged; D012997:Solvents
D004987:Ethers; D008738:Methyl Ethers; D012997:Solvents; C043243:methyl tert-butyl ether