Stem cell delivery vehicle.
Bone marrow contains a rare class of stem cells capable of developing into a number of mesenchymal tissues. The delivery of these cells to appropriate skeletal sites will require uniquely compatible biomaterials. Porous calcium phosphate ceramics may provide such a vehicle for the repair of bone. The experimental basis for this proposal is discussed.
Caplan
A I
AI
Department of Biology, Case Western Reserve University Cleveland, Ohio 44106.
D000818:Animals; D001672:Biocompatible Materials; D016026:Bone Marrow Transplantation / Q000379:methods*; D001842:Bone and Bones / Q000166:cytology*; D002130:Calcium Phosphates; D002516:Ceramics; D014677:Pharmaceutical Vehicles; D011784:Quail; D033581:Stem Cell Transplantation
D001672:Biocompatible Materials; D002130:Calcium Phosphates; D014677:Pharmaceutical Vehicles; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; C020243:calcium phosphate; C485829:calcium phosphate, dibasic, anhydrous