Dominant resistance to oxythiamin in Saccharomyces cerevisiae and its mapping.
A dominant mutation, responsible for the resistance to oxythiamin in Saccharomyces cerevisiae was mapped on the right arm of chromosome IV, 4.6 cM centromere-distally to trp1. The corresponding gene is not involved in the control of intracellular content of total thiamin during growth on a minimal medium without thiamin.
Department of Biochemistry and Microbiology, Institute of Chemical Technology, Prague.
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Silhánková
D002874:Chromosome Mapping; D004352:Drug Resistance, Microbial; D005799:Genes, Dominant; D005800:Genes, Fungal; D010119:Oxythiamine / Q000494:pharmacology*; D012441:Saccharomyces cerevisiae / Q000187:drug effects* / Q000235:genetics; D013831:Thiamine / Q000032:analysis; D013844:Thiazoles / Q000494:pharmacology*
D013844:Thiazoles; D010119:Oxythiamine; D013831:Thiamine