Retrospectives and perspectives on the biological activity of histidine-containing dipeptides.
1. An evaluation of the biological function of histidine-containing dipeptides, is presented. 2. These have been found to be potent pH-buffering compounds, strong antioxidants and membrane stabilizers. 3. Analysis of the biological and biomedical properties of carnosine and other related dipeptides suggests their use as universal membrane repairing compounds.
Boldyrev
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AA
Department of Biochemistry, Moscow State University, U.S.S.R.
D000818:Animals; D002021:Buffers; D002336:Carnosine / Q000494:pharmacology; D004151:Dipeptides / Q000494:pharmacology*; D006639:Histidine; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D014714:Vertebrates
D002021:Buffers; D004151:Dipeptides; D006639:Histidine; D002336:Carnosine