Factors affecting transmission of Wuchereria bancrofti by anopheline mosquitoes. 3. Uptake and damage to ingested microfilariae by Anopheles gambiae, An. arabiensis, An. merus and An. funestus in east Africa.
Laboratory observations were made on the uptake of microfilariae (mf) of Wuchereria bancrofti by Anopheles gambiae, An. arabiensis, An. merus and An. funestus. Over host mf densities ranging from 450/ml to 1735 mf/ml neither the percentage of mosquitoes ingesting mf nor the mean number of mf per mosquito was correlated to host mf density. All mosquito species damaged mf during ingestion but the proportion harmed was independent of host mf density. The mean proportion damaged was 0.67 in An. gambiae, 0.51 in An. merus, 0.47 in An. Arabiensis and 0.26 in An. funestus. A comparison of the mean number of undamaged mf ingested and the number of larvae in the thoracic muscles revealed that not all undamaged mf were able to reach the thoracic muscles.
Medical Research Council Laboratories, Banjul, The Gambia.
J H
JH
Bryan
P
P
McMahon
A
A
Barnes
D000351:Africa, Eastern; D000818:Animals; D000852:Anopheles / Q000469:parasitology* / Q000502:physiology; D004605:Elephantiasis, Filarial / Q000635:transmission*; D005368:Filariasis / Q000635:transmission*; D007303:Insect Vectors / Q000469:parasitology* / Q000502:physiology; D008842:Microfilariae / Q000502:physiology; D013045:Species Specificity; D014957:Wuchereria / Q000502:physiology*; D014958:Wuchereria bancrofti / Q000254:growth & development / Q000502:physiology*