An association between mutagenicity and carcinogenic potency.
A comparison between mutagenic and non-mutagenic rodent carcinogens studied by the U.S. National Toxicology Program revealed that as a group, rat carcinogens mutagenic in Salmonella typhimurium are more potent than their non-mutagenic counterparts.
Rosenkranz
H S
HS
Department of Environmental Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH 44106.
Ennever
F K
FK
D000818:Animals; D002273:Carcinogens; D004341:Drug Evaluation; D051379:Mice; D009153:Mutagens; D009369:Neoplasms / Q000139:chemically induced; D051381:Rats; D012486:Salmonella typhimurium
D002273:Carcinogens; D009153:Mutagens