Immune abnormalities in the pathogenesis of juvenile rheumatoid arthritis.
This article reviews the immune abnormalities involved in the pathogenesis of juvenile rheumatoid arthritis (JRA). We review both the humoral and cellular immune systems of children with JRA with emphasis on the possible role of these immune abnormalities in the pathogenesis of JRA.
Department of Pediatrics, Children's National Medical Center, Washington, DC 20010.
R N
RN
Lipnick
G C
GC
Tsokos
D001171:Arthritis, Juvenile / Q000209:etiology* / Q000276:immunology / Q000503:physiopathology; D002675:Child, Preschool; D006801:Humans; D007154:Immune System Diseases / Q000150:complications*; D007111:Immunity, Cellular / Q000502:physiology; D012698:Serologic Tests