Biomaterials for implanted closed loop insulin delivery system: a review.
The potential of five different groups of materials--carbons, glass and ceramics, polymers, hydrogels and collagen--as biomaterials in artificial implant applications is examined. In addition to the physical and/or structural properties of these materials, the blood and tissue responses to implants made of these biomaterials for various applications are presented. Emphasis is placed on materials related to the intended application; as catheter tips and biosensors for glucose to be used in conjunction with an implantable insulin delivery system as a complete artificial pancreas.
University of New Mexico, Department of Chemical & Nuclear Engineering, Albuquerque 87131.
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E
Wilkins
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W
Radford
D000818:Animals; D001672:Biocompatible Materials / Q000009:adverse effects; D001696:Biomechanical Phenomena; D005549:Foreign-Body Reaction / Q000209:etiology; D006801:Humans; D015918:Infusion Pumps, Implantable; D007332:Insulin Infusion Systems; D008422:Materials Testing; D013499:Surface Properties
D001672:Biocompatible Materials