[The effect of earlier pregnancies on the prevalence of goiter and nodules in thyroid-healthy women].
Ultrasound scans of the thyroid were performed in 106 women of mean age 41.9 (36-50) years, 53 with and 53 without a history of previous pregnancy, with the object of ascertaining the prevalence of goitre and thyroid nodules. Goitres (defined as a thyroid volume exceeding 18 ml) were found in 22 of the women with previous pregnancies (41.5%). Thyroid nodules were found in 23 of the 106 women (21.6%). Whereas only five of the 53 women without previous pregnancies (9.4%) had thyroid nodules, they were noted in 18 of the 53 women who had had children (33.9%), the difference being statistically significant (P less than 0.05). Thyroid cysts were found in 12 of the 106 women (11.3%), though there was no significant difference between the two groups. Thyroid calcification was noted in only one woman. The results highlight the consequences of iodine deficiency in a region where iodine intake is inadequate (Kiel) and show that the deficiency is accentuated during pregnancy.
Abteilung Allgemeine Innere Medizin, Zentrum Konservative Medizin I der Universität Kiel.
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D000328:Adult; D005260:Female; D005860:Germany, West / Q000453:epidemiology; D006042:Goiter / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D008875:Middle Aged; D010298:Parity; D011247:Pregnancy; D015995:Prevalence; D013959:Thyroid Diseases / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D013961:Thyroid Gland / Q000473:pathology; D014463:Ultrasonography
Einfluss früherer Schwangerschaften auf Struma- und Knotenhäufigkeit bei schilddrüsengesunden Frauen.