Pyoderma gangrenosum complicating Felty's syndrome.
The case of a 54-year-old woman with Felty's syndrome whose course was complicated by mucocutaneous lesions clinically typical of pyoderma gangrenosum is described. Necrotizing sinusitis and saddle nose deformity were distinctive clinical features. Lymphocytic vasculitis and rheumatoid nodule formation observed within panniculus at the base of a cutaneous lesion and in a nasal mucosal lesion were unexpected histopathologic findings.
Kramer
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Department of Medicine, University of Medicine and Dentistry of New Jersey-New Jersey Medical School, Newark.
Berman
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Rosenstein
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ED
D005258:Felty Syndrome / Q000150:complications*; D005260:Female; D005734:Gangrene; D006801:Humans; D008875:Middle Aged; D009336:Necrosis; D009667:Nose Deformities, Acquired / Q000209:etiology; D015434:Panniculitis / Q000150:complications / Q000473:pathology; D011711:Pyoderma / Q000150:complications / Q000473:pathology*; D012852:Sinusitis / Q000150:complications / Q000473:pathology