Renin-secreting retroperitoneal leiomyosarcoma: an unusual cause of hypertension.
A 41 year old man with severe hypertension due to a renin-secreting retroperitoneal leiomyosarcoma is described. Clinical, immunohistochemical, electron microsopic and autopsy findings are presented. The origin of juxtaglomerular cells from vascular smooth muscle is briefly discussed.
Geddy
P M
PM
Department of Histopathology, Freeman Hospital, Newcastle-upon-Tyne, UK.
Main
J
J
D000328:Adult; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D007890:Leiomyosarcoma / Q000150:complications / Q000378:metabolism*; D008297:Male; D012083:Renin / Q000378:metabolism*; D012186:Retroperitoneal Neoplasms / Q000150:complications / Q000378:metabolism*
D012083:Renin