Neurologic aspects of sleep apnea and related respiratory disturbances.
Several types of neurologic diseases can contribute to disturbed respiration during sleep. Abnormal function of respiratory and upper airway muscles can occur with neuromuscular diseases and lead to upper airway obstruction and alveolar hypoventilation during sleep. Central nervous system disorders that cause dysarthria and dysphagia can also lead to obstructive and central sleep apnea, even in the absence of the usual anatomic deformities associated with OSA. Appropriate treatment requires an understanding of the effect of the underlying disease process on upper airway and respiratory function.
Aldrich
M S
MS
Department of Neurology, University of Michigan Medical Center, Ann Arbor.
D000403:Airway Resistance / Q000502:physiology; D002493:Central Nervous System Diseases / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D007040:Hypoventilation / Q000209:etiology / Q000503:physiopathology; D009468:Neuromuscular Diseases / Q000150:complications* / Q000503:physiopathology; D012120:Respiration Disorders / Q000209:etiology / Q000503:physiopathology; D012891:Sleep Apnea Syndromes / Q000209:etiology* / Q000503:physiopathology; D014797:Vital Capacity