Inward rectifier potassium current on embryonic Xenopus muscle cells at different times in culture.
Whole cell current recordings of Xenopus muscle cells in 1-day-old cultures revealed an inward K+ current, with properties similar to the inward rectifier of adult muscle. However, at the earliest ages (less than 10 h in culture) the time-dependent decline in the current amplitude, indicative of a depletion of extracellular K+, was not present. The change in the time-dependent decline of the current amplitude may result from a change in the channel itself or a change in the distribution of the channel in the membrane.
Faculty of Medicine, Memorial University of Newfoundland, St. John's, Canada.
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Moody-Corbett
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Gilbert
D000818:Animals; D004625:Embryo, Nonmammalian / Q000502:physiology; D008564:Membrane Potentials / Q000187:drug effects; D009132:Muscles / Q000166:cytology / Q000502:physiology*; D011188:Potassium / Q000494:pharmacology / Q000502:physiology*; D014982:Xenopus laevis / Q000502:physiology*
D011188:Potassium