Comparison of water quality criterion and lifetime health advisory for hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX).
The U.S. Environmental Protection Agency (USEPA) has recently recommended a lifetime health advisory (HA) for hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX). The purpose of this brief article is to present the basis for the calculation of the HA so that the reader can compare it with a water quality criterion (WQC) that has been proposed (E. L. Etnier, 1989, Regul. Toxicol. Pharmacol. 9, 147-157). In the earlier article, a water quality criterion of 105 micrograms/liter for RDX in drinking water was proposed, and in the present article the methodology by which USEPA calculated a lifetime HA of 2 micrograms/liter is presented. The differences in the derivation of the WQC and the HA are discussed.
Health and Safety Research Division, Oak Ridge National Laboratory, Tennessee 37831-6050.
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Etnier
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Hartley
D000818:Animals; D006801:Humans; D014227:Triazines / Q000032:analysis / Q000633:toxicity*; D014873:Water Pollutants / Q000633:toxicity*; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000633:toxicity*; D014881:Water Supply / Q000032:analysis*
D014227:Triazines; D014873:Water Pollutants; D014874:Water Pollutants, Chemical; C009160:cyclonite