Immunocytochemical localisation of collagens (I-V) in the human iris.
In this study we investigated the distribution of collagen types I-V in the human iris at the fine-structural level using cryoultramicrotomy and London Resin White plastic embedding. Collagen type I was shown to be present in the basement membrane of iris vessels, in contrast to type III, which was absent; both types I and III were present in the iris stroma. Collagen type IV was a major component of basement membranes of vascular cells, myoepithelial cells, fibroblasts and epithelial cells. Types II and V were absent. Both cryo and plastic embedding techniques produced closely comparable results.
Department of Ophthalmology, Western Infirmary, Glasgow, Scotland.
A G
AG
Konstas
G E
GE
Marshall
W R
WR
Lee
D000328:Adult; D000368:Aged; D001485:Basement Membrane / Q000032:analysis / Q000648:ultrastructure; D003094:Collagen / Q000032:analysis*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007498:Iris / Q000032:analysis* / Q000098:blood supply / Q000648:ultrastructure; D008297:Male; D008875:Middle Aged; D013048:Specimen Handling
D003094:Collagen