Using factor scores to detect G X E interactive origin of "pure" genetic or environmental factors obtained in genetic covariance structure analysis.
Moment expressions for individual factor scores can serve as simple tests for the presence of a particular class of interaction factors that are disguised as pure genetic and/or environmental factors. That is, individual genetic and environmental factor scores may be used to construct fourth-order moments of these factors in order to test whether a common genetic or environmental factor in the multivariate genetic factor model is in fact of the interactive origin concerned. Expected fourth-order moments are derived for cases with and without interaction. Application of fourth-order moments of factor scores to detect interactive origin of common factors is illustrated with simulated twin data.
Molenaar
P C
PC
Department of Psychology, University of Amsterdam, The Netherlands.
Boomsma
D I
DI
Neeleman
D
D
Dolan
C V
CV
D004777:Environment; D005821:Genetic Techniques; D014644:Genetic Variation / Q000235:genetics*; D005838:Genotype; D008433:Mathematics; D008957:Models, Genetic; D015999:Multivariate Analysis