Detection with a monoclonal antibody of a polysaccharide antigen, excreted in the urine, in the schistosomiasis intercalatum focus of Edea (Cameroon).
The detection in the urine specimens of a sample of the inhabitants of Edea of a polysaccharide antigen characteristic for the genus Schistosoma, with monoclonal antibody by means of the inhibition of a passive haemagglutination test, shows that this technique is very sensitive for measuring prevalence of schistosomiasis due to S. intercalatum. In Edea, looking for eggs in stool specimens gives a low prevalence rate of the disease because of the low parasitic load. The prevalence by age, according to the voiding of eggs, is evoluting parallel to the excretion of the antigen.
Laboratorie de Parasitologie Médicale, Université de Bordeaux II, France.
C
C
Ripert
P
P
Vincendeau
F
F
Macaigne
M
M
Appriou
H
H
Biessy
J
J
Tribouley
J
J
Tribouley-Duret
T
T
Garnier
D000293:Adolescent; D000328:Adult; D000818:Animals; D000909:Antibodies, Helminth / Q000276:immunology; D000911:Antibodies, Monoclonal / Q000276:immunology*; D000947:Antigens, Helminth / Q000652:urine*; D002163:Cameroon / Q000453:epidemiology; D002648:Child; D005260:Female; D005455:Fluorescent Antibody Technique; D006386:Hemagglutination Tests; D006801:Humans; D008297:Male; D008875:Middle Aged; D011134:Polysaccharides / Q000652:urine*; D015995:Prevalence; D012547:Schistosoma / Q000276:immunology*; D012552:Schistosomiasis / Q000175:diagnosis / Q000453:epidemiology / Q000652:urine*
D000909:Antibodies, Helminth; D000911:Antibodies, Monoclonal; D000947:Antigens, Helminth; D011134:Polysaccharides