Transscleral microwave cyclodestruction.
A 4.6-gigahertz (GHz) microwave applicator was used to ablate the ciliary body in rabbit eyes. High-frequency electromagnetic radiation provides a favorable dose distribution to induce local heating of the ciliary body. For treatment, a 3-mm diameter disc-shaped applicator was placed on the conjunctiva and over the ciliary body. Conjunctival temperatures were monitored during treatment with a built-in thermocouple thermometer located at the center of the disc-shaped antenna. This allowed direct measurement (dosimetry) of the conjunctival temperature during treatment. Using this microwave-based heat-delivery system, doses in a range of 60 degrees for 30 or 60 seconds appeared to cause ciliary body damage with relative sparing of the conjunctiva and sclera.
Finger
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PT
Department of Ophthalmology, North Shore University Hospital-Cornell University Medical College, Manhasset, New York 11030.
Smith
P D
PD
Paglione
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RW
Perry
H D
HD
D000818:Animals; D002924:Ciliary Body / Q000473:pathology / Q000528:radiation effects*; D003228:Conjunctiva / Q000473:pathology / Q000528:radiation effects; D004867:Equipment Design; D008872:Microwaves / Q000009:adverse effects; D009336:Necrosis; D011817:Rabbits; D012590:Sclera / Q000473:pathology / Q000528:radiation effects; D013679:Technology, Radiologic; D013696:Temperature