[Pulmonary Pseudomonas infections].
145 strains of pathogenic pseudomonas had been isolated from the sputum or bronchoscopic aspirate of 1423 patients with pulmonary infections. They were classified into 8 types, among which 31.7% was pseudomonas aeruginosa. Pseudomonas aeruginosa was the dominant causative organism in pulmonary infections of the aged while in presenile ones the organism was mainly Pseudomonas fetid. The incidence of nosnocomial pseudomonas infection in patients of COPD with respiratory failure was 40%, of COPD with pulmonary infection 9.1% and of others 6.6%. 24 pseudomonas carriers with COPD (colonies less than or equal to 10(6)/ml in sputum) had been followed up. 16 out of them became negative in sputum culture without any treatment, while the remaining 8 developed pulmonary pseudomonas infections. 21 patients (14.5%) were found to have other types of pseudomonas infections during antibiotic treatment. Sensitivity tests showed that third-generation cephalosporins and aminoglycosides had definite antimicrobial activity against pseudomonas, the former being more stable and effective than the latter.
Yu
G H
GH
Guangzhuo Institute of Respiratory Diseases.
Yuan
J P
JP
Zhong
N S
NS
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002511:Cephalosporins / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D011014:Pneumonia / Q000188:drug therapy / Q000382:microbiology*; D011549:Pseudomonas / Q000187:drug effects / Q000302:isolation & purification; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000382:microbiology*; D012131:Respiratory Insufficiency / Q000188:drug therapy / Q000382:microbiology
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D002511:Cephalosporins