[Genetic counseling of diabetics].
The information and counselling of diabetic patients and their families requires for the practitioner to know about some fundamental aspects of diabetes and in particular, to distinguish between the different types of diabetes with different causes, pathogenetic mechanism and modes of inheritance. Recent developments in the fields of immunogenetics have improved the understanding of type I diabetes, an auto-immune disease associated with HLA and made possible the identification of genetically susceptible individuals. The etiology of type II diabetes, by far the most frequent form, remains unknown. In the absence of genetical markers, the screening of predisposed subjects is, however, useful in order to propose preventive measures.
Service Endocrinologie et Diabète de l'Enfant et INSERM U30, Hôpital des Enfants-Malades, Paris.
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I
Deschamps
J J
JJ
Robert
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J
Hors
D003920:Diabetes Mellitus / Q000235:genetics* / Q000276:immunology; D003922:Diabetes Mellitus, Type 1 / Q000235:genetics; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics; D005817:Genetic Counseling; D020022:Genetic Predisposition to Disease; D006680:HLA Antigens / Q000235:genetics; D006801:Humans
D006680:HLA Antigens
Le conseil génétique pour les diabétiques.