[Experience with the impression cytology test for detecting vitamin A deficiency in children].
Impression cytology has been suggested as a relatively simple, cheap, practical and non invasive technique for documenting physiologically significant vitamin A deficiency. The vitamin A status of 41 patients was evaluated by serum retinol concentration by high power liquid chromatography (HPLC) and conjunctival impression cytology was performed on each child. All children with normal vitamin A status had normal conjunctival impression cytology. The sensibility of this method was 100%. However, in the 8 vitamin A deficient patients by impression cytology, only 6 of them showed low serum vitamin A levels. Impression cytology appears to detect preclinical vitamin A deficiency that this technique may by of potential usefulness as a screening tool for preclinical vitamin A deficiency populations.
Servicio de Bioquímica, Hospital Infantil La Paz, Madrid.
A
A
Cañete Díaz
R
R
Codoceo Alquinta
L C
LC
Carvalho Galvao
P
P
Jara Vega
M C
MC
Díaz Fernández
S
S
Carrasco Gandía
R
R
Lama Moré
R
R
Satriano Mónaco
I
I
Polanco Allue
D000293:Adolescent; D002648:Child; D002664:Child Nutritional Physiological Phenomena; D002675:Child, Preschool; D002851:Chromatography, High Pressure Liquid; D003228:Conjunctiva / Q000166:cytology; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening; D009748:Nutrition Disorders / Q000150:complications / Q000209:etiology; D009751:Nutritional Requirements; D013030:Spain; D014802:Vitamin A Deficiency / Q000175:diagnosis* / Q000209:etiology
Nuestra experiencia con el test de impresión citológica para detectar deficiencia de vitamina A en niños.