[Effects of crush syndrome on insulin receptor interactions in cells].
Comparative study of binding insulin receptor mononuclears, erythrocytes and hepatocytes of crush-syndrome revealed great difference in these parameters. In the early period of crush-syndrome (stress period insulin insufficiency hyperglycemia, insulin resistance, decrease in the activity of insulin binding in the mononuclears and increase in the activity of erythrocytes. By the 6 hour crush-syndrome (toxemic period) hyperinsulinemia, hyperglycemia, are observed as well as prolongation of the decrease in the activity of insulin binding of mononuclears.
Mikaelian
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NP
D000818:Animals; D001665:Binding Sites; D003444:Crush Syndrome / Q000503:physiopathology*; D004912:Erythrocytes / Q000378:metabolism; D006943:Hyperglycemia / Q000209:etiology; D007328:Insulin / Q000097:blood / Q000378:metabolism*; D007333:Insulin Resistance; D007963:Leukocytes, Mononuclear / Q000378:metabolism; D008099:Liver / Q000166:cytology / Q000378:metabolism; D008297:Male; D051381:Rats; D011972:Receptor, Insulin / Q000502:physiology*; D012774:Shock, Traumatic / Q000503:physiopathology*; D013997:Time Factors
D007328:Insulin; D011972:Receptor, Insulin
Vliianie krash-sindroma na insulinretseptornoe vzaimodeĭstvie v kletkakh.