Winter depression responds to an open trial of tranylcypromine.
Seasonal affective disorder (SAD) is a disturbance of mood bearing a fixed relationship to season. Winter depression is characterized by the onset of a depressive syndrome in the fall or winter and spontaneous remission in the spring, this condition responds to full-spectrum, bright artificial light. In the first study assessing responsiveness of winter depression to a standard pharmacologic treatment for depression, the authors found that 14 patients meeting National Institute of Mental Health criteria for winter depression responded to treatment with tranylcypromine.
Dilsaver
S C
SC
Department of Psychiatry, Ohio State University, Columbus.
Jaeckle
R S
RS
D000328:Adult; D002986:Clinical Trials as Topic; D003866:Depressive Disorder / Q000188:drug therapy* / Q000209:etiology / Q000523:psychology; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010789:Phototherapy; D011569:Psychiatric Status Rating Scales; D012621:Seasons; D014191:Tranylcypromine / Q000627:therapeutic use*
D014191:Tranylcypromine