Transferrin-reticulocyte cycle time in rat reticulocytes.
The uptake and release of 131I-labelled diferric transferrin by rat reticulocytes was examined both in vitro and in vivo. Cycle time in vitro was estimated to be 2.5 min in iron-deficient reticulocytes and 2.3 min in phenylhydrazine-produced reticulocytes. In vivo reticulocyte uptake and release of labelled diferric transferrin injected in the iron-deficient rat averaged 1.7 min.
USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX.
T
T
Intragumtornchai
H A
HA
Huebers
C A
CA
Finch
D000818:Animals; D001059:Apoproteins / Q000378:metabolism; D001692:Biological Transport; D004912:Erythrocytes / Q000378:metabolism; D066298:In Vitro Techniques; D007457:Iodine Radioisotopes; D000090463:Iron Deficiencies; D007700:Kinetics; D008297:Male; D011865:Radioisotope Dilution Technique; D051381:Rats; D011919:Rats, Inbred Strains; D012156:Reticulocytes / Q000378:metabolism*; D014168:Transferrin / Q000378:metabolism*
D001059:Apoproteins; D007457:Iodine Radioisotopes; D014168:Transferrin; C028284:apotransferrin