[Drug treatment of hyperlipidemia].
The working panel of the Swiss Foundation for Cardiology has elaborated in 1989 new directives for the treatment of hyperlipaemias. Cholesterol values over 6.5 mmol/l with a cholesterol/HDL ratio over 5 and, in case of coronary heart disease, cholesterol values over 5.2 mmol/l should first be treated by diet. If after 3-6 months, in spite of dietary treatment, cholesterol values remain superior to 6.5 mmol/l or the cholesterol/HDL ratio superior to 6.5, drug treatment must be considered in case of coronary heart disease or arteriosclerosis, considerably abnormal lipid values (cholesterol greater than 7.8 mmol/l; in case of coronary heart disease: cholesterol greater than 6.5 mmol/l), other risk factors, positive family history for coronary heart disease and younger men. Most of the medicaments available today reduce total cholesterol by 10-30%. Combined therapies can be indicated, if in the presence of high risks the different possibilities of monotherapy have not led to the desired success.
Ospedale Beata Vergine, Mendrisio.
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D000328:Adult; D000924:Anticholesteremic Agents / Q000627:therapeutic use*; D004311:Double-Blind Method; D006801:Humans; D006937:Hypercholesterolemia / Q000188:drug therapy*; D006949:Hyperlipidemias / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D016032:Randomized Controlled Trials as Topic
D000924:Anticholesteremic Agents; D000960:Hypolipidemic Agents
Medikamentöse Behandlung der Hyperlipidämie.