Inconsistent response to divalproex sodium in hemichorea/hemiballism.
We report 6 patients with hemichorea/hemiballism of vascular origin who were treated with divalproex sodium (Depakote). Four of 6 responded initially. Marked improvement was seen in 2 patients only and in 1 of these hemiballism recurred despite continuing therapy. Divalproex sodium is not uniformly effective in the treatment of hemichorea/hemiballism.
Sethi
K D
KD
Department of Neurology, Medical College of Georgia, Augusta 30912.
Patel
B P
BP
D000368:Aged; D002819:Chorea / Q000188:drug therapy* / Q000503:physiopathology / Q000601:surgery; D004305:Dose-Response Relationship, Drug; D006801:Humans; D008297:Male; D009069:Movement Disorders / Q000188:drug therapy* / Q000503:physiopathology / Q000601:surgery; D013788:Thalamus / Q000601:surgery; D014635:Valproic Acid / Q000627:therapeutic use*
D014635:Valproic Acid