title: [The epidemiological study on hepatitis B virus infection in Miyako district--relationship to the mass survey of filariasis].
abstract: It has been well known that the transmission of HB virus is associated with mass inoculation and other medical procedures. In order to make clear the relation between HBV infection and the mass survey for filariasis on which sera of the examinees were drawn from their earlobes for the detecting of microfilaria with inadequately sterilized instruments, a epidemiological study was conducted in Miyako district. Okinawa prefecture, Japan, in which both HBV infection and filariasis were prevalent. A total of 2,231 inhabitants were investigated for HBV seromarkers. The over all positive rate of HBs antigen was 6.3% with the highest rate of 15.5% in the group of age 25 to 29. On the other hand, the prevalence rate of HBs antibody continued to increase along with age group, and remained to be over 60% after 30 years of age. The positive rates of both HBs antigen and antibody in the subject district were higher than those in other place of Okinawa prefecture or Japan. Comparing yearly attack rates of HBV chronologically, which were calculated from the age-specific HBV exposure rates in the district, the annual incidence of HBV infection was 6.1% (%/year) between 1954 to 1958, 5.2% (%/year) between 1959 to 1963, and then 4.4 (%/year) in the period of 1964 to 1968 in which the proportion of examinees for the survey of filariasis was the highest. In conclusion, the mass survey for filariasis was not the main factor contributing to the high prevalence of HBV infection in Miyako district.
authors.affiliation: First Department of Internal Medicine, Faculty of Medicine, School of Medicine, University of Ryukyus.
authors.forename: H
authors.initials: H
authors.lastname: Sakugawa
authors.forename: K
authors.initials: K
authors.lastname: Kadena
authors.forename: T
authors.initials: T
authors.lastname: Oyakawa
authors.forename: T
authors.initials: T
authors.lastname: Kuniyoshi
authors.forename: K
authors.initials: K
authors.lastname: Akamine
authors.forename: T
authors.initials: T
authors.lastname: Uehara
authors.forename: F
authors.initials: F
authors.lastname: Kinjo
authors.forename: A
authors.initials: A
authors.lastname: Saito
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D001800:Blood Specimen Collection; D002417:Cattle; D002648:Child; D002675:Child, Preschool; D005260:Female; D005368:Filariasis / Q000517:prevention & control*; D006509:Hepatitis B / Q000453:epidemiology* / Q000635:transmission; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D015995:Prevalence; D016036:Seroepidemiologic Studies