title: Experimental prostatitis in nonhuman primates: I. Bacterial adherence in the urethra.
abstract: Both man and monkey possess urothelial (transitional cell) receptors for P-fimbriae of Escherichia coli; however, the male urethra has pseudostratified columnar cells. We studied adherence using scanning electron microscopy and found that P-fimbriae were the principal mediators of adherence to these cells as well. The monkey, therefore, should be a good model for the study of the ascending route of infection in prostatitis, the route thought to occur in man.
authors.affiliation: Department of Urology, Delta Regional Primate Research Center, Covington, Louisiana 70433.
authors.forename: J P
authors.initials: JP
authors.lastname: Dilworth
authors.forename: D E
authors.initials: DE
authors.lastname: Neal
authors.forename: E N
authors.initials: EN
authors.lastname: Fussell
authors.forename: J A
authors.initials: JA
authors.lastname: Roberts
mesh_terms: D000818:Animals; D001422:Bacterial Adhesion; D004195:Disease Models, Animal; D004926:Escherichia coli / Q000502:physiology* / Q000648:ultrastructure; D004927:Escherichia coli Infections / Q000150:complications* / Q000473:pathology; D008252:Macaca fascicularis; D008297:Male; D008855:Microscopy, Electron, Scanning; D011472:Prostatitis / Q000150:complications / Q000382:microbiology* / Q000473:pathology; D014521:Urethra / Q000382:microbiology* / Q000648:ultrastructure