Synthesis of carboxy-residue-modified coenzyme derivatives as probes to the mechanism of glutathione enzymes.
a general procedure for the preparation of the monoglycyl and dimethyl ester and amide derivatives of s-(4-bromobenzyl)glutathione are reported, in addition to purification procedures.
D'Silva
C
C
Institute of Molecular and Biomolecular Electronics, University of Wales, Bangor, Gwynedd, U.K.
D001665:Binding Sites; D003067:Coenzymes / Q000737:chemistry; D005978:Glutathione / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000302:isolation & purification; D005982:Glutathione Transferase / Q000378:metabolism; D007791:Lactoylglutathione Lyase / Q000378:metabolism; D015394:Molecular Structure
D003067:Coenzymes; C020233:S-(4-bromobenzyl)glutathione; D005982:Glutathione Transferase; D007791:Lactoylglutathione Lyase; D005978:Glutathione