[Vitamin B6 level in the cerebrospinal fluid and plasma of children with acute leukemia].
Content of pyridoxal in cerebrospinal fluid exceeded its level in blood plasma of healthy children. Transport of pyridoxal through hematoencephalic barrier was decreased in children with acute leukosis, especially, with neuroleukosis, while content of pyridoxal-5-phosphate was similar to normal values. Possible mechanisms are considered which are involved in stabilization of pyroxal-5-phosphate content in cerebrospinal fluid of patients with acute leukosis, when transport of pyridoxal was impaired in central nervous system.
Chuvykin
M B
MB
Shestakov
V L
VL
D000208:Acute Disease; D000293:Adolescent; D001932:Brain Neoplasms / Q000097:blood / Q000134:cerebrospinal fluid*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007938:Leukemia / Q000097:blood / Q000134:cerebrospinal fluid*; D011732:Pyridoxal Phosphate / Q000097:blood / Q000134:cerebrospinal fluid; D011736:Pyridoxine / Q000097:blood / Q000134:cerebrospinal fluid*
D011732:Pyridoxal Phosphate; D011736:Pyridoxine
Soderzhanie vitamina B6 v spinnomozgovoĭ zhidkosti i plazme krovi pri ostrom leĭkoze u deteĭ.