The effect of fibrin glue and peritoneal grafts in the prevention of intraperitoneal adhesions.
We studied the effect of fibrin sealant and peritoneal grafts applied by fibrin glue on adhesion formation in the rat. Sealing and patching of ischaemic lesions of the uterus resulted in a significant increase in adhesion formation. We conclude, that fibrin sealant and peritoneal grafts can not be given general approval for prophylaxis of intraperitoneal adhesions.
Gauwerky
J F
JF
Department of Obstetrics and Gynecology, University of Heidelberg, FRG.
Mann
J
J
Bastert
G
G
D000818:Animals; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage*; D008643:Mesentery / Q000637:transplantation*; D010537:Peritoneum / Q000473:pathology / Q000601:surgery*; D011183:Postoperative Complications / Q000517:prevention & control*; D051381:Rats; D011919:Rats, Inbred Strains; D013524:Surgical Flaps / Q000379:methods*; D000267:Tissue Adhesions; D014945:Wound Healing / Q000187:drug effects*
D015718:Fibrin Tissue Adhesive