title: Microcin H47, a chromosome-encoded microcin antibiotic of Escherichia coli.
abstract: Microcin H47 (MccH47) is a novel microcin antibiotic produced by a natural Escherichia coli isolate. In contrast to all the other colicins and microcins examined to date, which are plasmid encoded, the genes for MccH47 synthesis and immunity are located on the chromosome. These genetic determinants were cloned and shown to extend over a continuous DNA region of ca. 10 kb.
authors.affiliation: Instituto de Investigaciones Biológicas Clemente Estable Ministerio de Educación y Cultura, Montevideo, Uruguay.
authors.forename: M
authors.initials: M
authors.lastname: Laviña
authors.forename: C
authors.initials: C
authors.lastname: Gaggero
authors.forename: F
authors.initials: F
authors.lastname: Moreno
mesh_terms: D000900:Anti-Bacterial Agents / Q000096:biosynthesis; D001430:Bacteriocins / Q000096:biosynthesis*; D002876:Chromosomes, Bacterial; D003001:Cloning, Molecular; D004269:DNA, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000235:genetics*; D009693:Nucleic Acid Hybridization; D015183:Restriction Mapping
chemical_list: D000900:Anti-Bacterial Agents; D001430:Bacteriocins; D004269:DNA, Bacterial; C020411:microcin