[The efficacy of and tolerance for fansimef in the treatment of tropical malaria in the south of the Socialist Republic of Vietnam].
The efficacy of and tolerance to fancimef in 49 patients was compared to the efficacy of and tolerance to quinine in combination with fansidar in 33 patients with moderate P. falciparum malaria. A good tolerance to and a high efficacy of fancimef have been shown, which was manifested in rapid fever arrest, disappearance of parasitemia, absence of the disease relapses, which were observed in 2 patients on quinine combined with fansidar. The advantage of fansimef is one-time administration of the total course dose.
Shcherbakov
A M
AM
Rabinovich
S A
SA
Chin
K A
KA
Nguyen
V K
VK
Chan
V B
VB
Dadasheva
N R
NR
Sokhanenkova
T L
TL
Nguyen
V T
VT
Vu
T T
TT
Vu
C
C
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use*; D002648:Child; D004338:Drug Combinations; D004351:Drug Resistance; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D008288:Malaria / Q000097:blood / Q000188:drug therapy* / Q000469:parasitology; D008297:Male; D015767:Mefloquine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008875:Middle Aged; D010963:Plasmodium falciparum; D011739:Pyrimethamine / Q000627:therapeutic use*; D013413:Sulfadoxine / Q000627:therapeutic use*; D014744:Vietnam; D000096926:Benzenesulfonamides
D000962:Antimalarials; D004338:Drug Combinations; D015767:Mefloquine; D011739:Pyrimethamine; D013413:Sulfadoxine; C046846:mefloquine-sulfadoxine-pyrimethamine; D000096926:Benzenesulfonamides
Effektivnost' i perenosimost' fansimefa pri lechenii tropicheskoĭ maliarii na iuge SRV.