title: [The induction of tolerance in mice for a human melanoma graft].
abstract: Mouse skin allografts and intramuscular BRO human melanoma xenografts were successfully established in phenotypically normal mice after inducing immunological tolerance in the recipients. Tolerance was achieved by inoculating allogenic embryonic liver cells after the whole-body irradiation. No immunological rejection was evident in BRO xenografts for 34 days after transplantation. During this period the BRO cells invaded neighboring tissues and formed distant micrometastases in the lungs.
authors.forename: T A
authors.initials: TA
authors.lastname: Bogush
authors.forename: A
authors.initials: A
authors.lastname: Lokshin
authors.forename: G B
authors.initials: GB
authors.lastname: Smirnova
authors.forename: S F
authors.initials: SF
authors.lastname: Iushkov
authors.forename: I A
authors.initials: IA
authors.lastname: Karpov
authors.forename: G Sh
authors.initials: GSh
authors.lastname: Ovumian
authors.forename: V N
authors.initials: VN
authors.lastname: Kastrykina
authors.forename: K L
authors.initials: KL
authors.lastname: Chimishkian
mesh_terms: D000818:Animals; D004622:Embryo, Mammalian; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology* / Q000528:radiation effects; D016031:Liver Transplantation / Q000276:immunology; D008545:Melanoma / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009368:Neoplasm Transplantation; D012878:Skin Neoplasms / Q000276:immunology*; D016038:Skin Transplantation / Q000276:immunology; D014183:Transplantation, Heterologous; D014184:Transplantation, Homologous
vernacular_title: Induktsiia tolerantnosti u mysheĭ k transplantatu melanomy cheloveka.