title: [Treatment of dry eye by temporary punctum plug. Comparison with a control group].
abstract: 35 patients with chronic dry eye were treated with punctum plug on one side only. The other side was a control: after simulation dilatation, the patient underwent a simulation insertion. This is an open study in which only the patient ignored the reality of treatment. The study was prospective. 28 females and 7 males were enrolled in this study. The age' average was 53. The follow-up average is 5.3 months. The etiologies were: idiopathic dry eye: 10 cases, Sjögren's syndrome: 11 cases, drug induced dry eye: 6 cases, filamentous keratitis: 4 cases. Other: 4 cases. Enrollment criteria were: functional symptomatology not answering to topical therapy (physiological serum drops) associated with one or more of the following items: positive Rose Bengal staining and/or Schirmer lower than 5 mm in 5 min and/or filamentary keratitis. Subjective improvement is significantly better after closing the two puncta on the same side (77%) than the other side (placebo) (17%) (p less than 0.001). This difference is also demonstrated for the improvement of Rose Bengal staining (p = 0.068) and for Schirmer's test (p = 0.002). These results demonstrated the effectiveness of this therapy versus placebo. Results after closing the 2 puncta on the same side are better than after closing one punctum.
authors.affiliation: Service d'Ophtalmologie de l'Hôtel-Dieu de Paris.
authors.forename: B
authors.initials: B
authors.lastname: Fayet
authors.forename: J A
authors.initials: JA
authors.lastname: Bernard
authors.forename: J
authors.initials: J
authors.lastname: Ammar
authors.forename: I
authors.initials: I
authors.lastname: Karpouzas
authors.forename: Y
authors.initials: Y
authors.lastname: Taylor
authors.forename: A
authors.initials: A
authors.lastname: Abenhaim
authors.forename: G
authors.initials: G
authors.lastname: Renard
authors.forename: Y
authors.initials: Y
authors.lastname: Pouliquen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D005163:Factor Analysis, Statistical; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008722:Methods; D008875:Middle Aged; D011446:Prospective Studies; D012828:Silicones / Q000627:therapeutic use*; D016037:Single-Blind Method; D014985:Xerophthalmia / Q000601:surgery*
chemical_list: D012828:Silicones
vernacular_title: Traitement des sécheresses lacrymales par occlusion réversible des méats lacrymaux. Résultats comparés à un groupe témoin.