title: [Netilmicin in a single daily dose for treatment of systemic infections].
abstract: The Authors report the results obtained in 35 patients of either sex suffering from various systemic infections and treated with netilmicin. Netilmicin has been intramuscularly administered in once daily dose of 4.5 mg/kg (mean daily dose 294.3 mg) for a mean duration of 17.8 days. The clinical resolution of the infections has been achieved in 97.1% (34 patients) of the study population; only one patient showed failure. Thirty-three of the 35 baseline causative pathogens have been eradicated. The local and systemic tolerability was good. The serum pharmacokinetics showed bactericidal levels of netilmicin and no serum accumulation.
authors.affiliation: Divisione di Medicina Infettivi, Ospedale Maggiore della Carità, Novara.
authors.forename: M
authors.initials: M
authors.lastname: Andreoni
authors.forename: S
authors.initials: S
authors.lastname: Andreoni
authors.forename: L
authors.initials: L
authors.lastname: Franchino
authors.forename: P T
authors.initials: PT
authors.lastname: Ricciardiello
authors.forename: A
authors.initials: A
authors.lastname: Fortina
mesh_terms: D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009428:Netilmicin / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D009428:Netilmicin
vernacular_title: Netilmicina in dose singola giornaliera nel trattamento di infezioni sistemiche.