title: Estimation of fecundic life span of Wuchereria bancrofti from longitudinal study of human infection in an endemic area of Pondicherry (south India).
abstract: The fecundic life span of adult female W. bancrofti was estimated by longitudinal study of microfilaraemia in a cohort of population (7,525) in Pondicherry. The estimation was based on a deterministic model, using the rate of loss in infection. The life span of the parasite was 10.2 yr without chemotherapy, while it was reduced to 5.3 yr following diethyl-carbamazine therapy. The analysis of mean microfilarial counts in microfilaraemic persons without chemotherapy indicates that the rate of production of microfilaria by the adult female is stable at least for a period of five years.
authors.affiliation: Vector Control Research Centre, Pondicherry.
authors.forename: P
authors.initials: P
authors.lastname: Vanamail
authors.forename: S
authors.initials: S
authors.lastname: Subramanian
authors.forename: P K
authors.initials: PK
authors.lastname: Das
authors.forename: S P
authors.initials: SP
authors.lastname: Pani
authors.forename: P K
authors.initials: PK
authors.lastname: Rajagopalan
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D004049:Diethylcarbamazine / Q000627:therapeutic use; D004605:Elephantiasis, Filarial / Q000188:drug therapy / Q000469:parasitology*; D005260:Female; D005298:Fertility; D006801:Humans; D007223:Infant; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D014958:Wuchereria bancrofti / Q000502:physiology*
chemical_list: D004049:Diethylcarbamazine