Tuberculous psoas muscle abscess following chemoprophylaxis with isoniazid in a patient with human immunodeficiency virus infection.
A 34-year-old man with human immunodeficiency virus infection and disseminated Mycobacterium avium and Mycobacterium intracellulare infection developed a right psoas muscle abscess due to Mycobacterium tuberculosis. The abscess occurred 18 months after completion of a 12-month course of chemoprophylaxis with isoniazid that was given because of a positive reaction with purified protein derivative of tuberculin. The adjacent vertebrae did not appear to be involved. The abscess was drained with a percutaneously inserted catheter, and he received standard antituberculous chemotherapy. Three weeks into therapy, a second drainage with a catheter was required. The isolation of two mycobacteria in this patient and the apparent failure of chemoprophylaxis with isoniazid are noted.
Johnson
S C
SC
Department of Medicine, Walter Reed Army Medical Center, Washington, D.C. 20307-5001.
Stamm
C P
CP
Hicks
C B
CB
D000038:Abscess / Q000150:complications* / Q000628:therapy; D000328:Adult; D003131:Combined Modality Therapy; D004322:Drainage; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use*; D008297:Male; D009135:Muscular Diseases / Q000150:complications* / Q000628:therapy; D014376:Tuberculosis / Q000150:complications* / Q000517:prevention & control / Q000628:therapy
D007538:Isoniazid