[Ocular symptoms in mitochondrial myopathy].
The corneal endothelial cells in 6 cases of mitochondrial myopathies were examined by specular microscope, and electron microscopic studies of the cornea were made in one autopsy case. The cornea was clear and the thickness was within the normal range. The endothelial cell mean size was larger in 3 out of 10 eyes than among controls and the variance of endothelial cell size was larger in all of 10 eyes than among controls. The difference was found to be statistically significant. Electron microscopical findings of the cornea revealed mitochondrial abnormalities. Inclusions were observed in the stromal keratocyte.
Ninomiya
H
H
Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan.
Kanai
A
A
Hayakawa
M
M
Nakajima
A
A
Yanashima
K
K
Sato
T
T
Miyake
I
I
D000328:Adult; D004728:Endothelium, Corneal / Q000166:cytology / Q000473:pathology / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D008931:Mitochondria, Muscle / Q000473:pathology* / Q000648:ultrastructure; D009135:Muscular Diseases / Q000473:pathology*