[An analysis of the structure of the metabolic products of methandrostenolone in the body of white rats].
The products of biotransformation of an anabolic steroidal drug methandrostenolone in the Wistar albino rat organism were studied. By using the developed methods of HPLC the products of a complete reduction of methandrostenolone were isolated and their chemical structures were determined. It was found that at the reduction of the system of methandrostenolone double bonds were formed all four possible isomers.
Krynetskiĭ
E Iu
EIu
Maruzhenkov
D S
DS
ProKhorov
B S
BS
Rylin
A F
AF
D000818:Animals; D001711:Biotransformation; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer / Q000379:methods; D007536:Isomerism; D008297:Male; D008696:Methandrostenolone / Q000032:analysis / Q000737:chemistry / Q000493:pharmacokinetics*; D051381:Rats; D011919:Rats, Inbred Strains
D008696:Methandrostenolone
Analiz struktury produktov metabolizma metandrostenolona v organizme belykh krys.