[Treatment of dry eye by temporary punctum plug. Comparison with a control group].
35 patients with chronic dry eye were treated with punctum plug on one side only. The other side was a control: after simulation dilatation, the patient underwent a simulation insertion. This is an open study in which only the patient ignored the reality of treatment. The study was prospective. 28 females and 7 males were enrolled in this study. The age' average was 53. The follow-up average is 5.3 months. The etiologies were: idiopathic dry eye: 10 cases, Sjögren's syndrome: 11 cases, drug induced dry eye: 6 cases, filamentous keratitis: 4 cases. Other: 4 cases. Enrollment criteria were: functional symptomatology not answering to topical therapy (physiological serum drops) associated with one or more of the following items: positive Rose Bengal staining and/or Schirmer lower than 5 mm in 5 min and/or filamentary keratitis. Subjective improvement is significantly better after closing the two puncta on the same side (77%) than the other side (placebo) (17%) (p less than 0.001). This difference is also demonstrated for the improvement of Rose Bengal staining (p = 0.068) and for Schirmer's test (p = 0.002). These results demonstrated the effectiveness of this therapy versus placebo. Results after closing the 2 puncta on the same side are better than after closing one punctum.
Fayet
B
B
Service d'Ophtalmologie de l'Hôtel-Dieu de Paris.
Bernard
J A
JA
Ammar
J
J
Karpouzas
I
I
Taylor
Y
Y
Abenhaim
A
A
Renard
G
G
Pouliquen
Y
Y
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D005163:Factor Analysis, Statistical; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008722:Methods; D008875:Middle Aged; D011446:Prospective Studies; D012828:Silicones / Q000627:therapeutic use*; D016037:Single-Blind Method; D014985:Xerophthalmia / Q000601:surgery*
D012828:Silicones
Traitement des sécheresses lacrymales par occlusion réversible des méats lacrymaux. Résultats comparés à un groupe témoin.