title: Detection and quantitation of ischemic left ventricular dysfunction using a new video intensity technique for regional wall motion evaluation.
abstract: Eighty patients with ischemic heart disease and 17 normal subjects were evaluated for left ventricular regional wall motion by means of a new method. The wall motion analysis is based on video intensity. This technique uses a temporally sliding analysis to evaluate the cardiac cycle in 100 msec intervals. Presence of coronary artery disease was defined as more than 50% measured diameter stenosis. Wall motion abnormalities in regions perfused by stenotic vessels were most common in early diastole (76%). Sensitivity of this method at rest in patients with coronary artery disease was 79.7% (p less than 0.0001) and overall accuracy was 84.2% (p less than 0.0001). Abnormalities in both systole and diastole were more common in regions perfused by severe lesions (greater than 75%) than in those perfused by moderately stenotic (less than 75%) vessels (p less than 0.05). A comparison of the new method with phase and amplitude analysis was performed in 15 patients and with two-frame analysis in 40 patients. This new method yielded a higher sensitivity than either of the other two methods.
authors.affiliation: University of California, San Diego.
authors.forename: V
authors.initials: V
authors.lastname: Bhargava
authors.forename: K S
authors.initials: KS
authors.lastname: Sunnerhagen
authors.forename: M
authors.initials: M
authors.lastname: Rashwan
authors.forename: R A
authors.initials: RA
authors.lastname: Podolin
authors.forename: R
authors.initials: R
authors.lastname: Shabetai
mesh_terms: D000328:Adult; D000368:Aged; D003327:Coronary Disease / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology*; D012680:Sensitivity and Specificity; D016277:Ventricular Function, Left / Q000502:physiology*; D014743:Videotape Recording / Q000295:instrumentation / Q000379:methods*