title: Host immunoglobulin on spleen-derived Leishmania donovani amastigotes.
abstract: Leishmania donovani, an intracellular pathogen in vertebrates, is found as an amastigote within cells of reticuloendothelial origin. The spleens of experimentally infected Syrian hamsters are frequently used as a source of amastigotes for studies of host-parasite interactions, but amastigotes isolated from hamster spleens have been found to have surface-bound host immunoglobulins, which may confound interpretation of such studies.
authors.affiliation: Department of Pathology, University of Virginia School of Medicine, Charlottesville.
authors.forename: R D
authors.initials: RD
authors.lastname: Pearson
authors.forename: D
authors.initials: D
authors.lastname: Roberts
mesh_terms: D000818:Animals; D006224:Cricetinae; D005455:Fluorescent Antibody Technique; D007136:Immunoglobulins / Q000276:immunology*; D007893:Leishmania donovani / Q000276:immunology*; D008647:Mesocricetus; D013154:Spleen / Q000469:parasitology*
chemical_list: D007136:Immunoglobulins