Spectral electroretinography in thioridazine toxicity.
In three patients with thioridazine toxicity, the electroretinogram (ERG) to red light was found to be below the average normal range. A significant increase in its amplitude appeared with cessation of therapy in two cases. A further deterioration of the ERG amplitude to all stimulus conditions (white, blue, and red lights) occurred when the dose of the medication was increased in the third patient.
Godel
V
V
Department of Ophthalmology, Ichilov Hospital, Tel Aviv University Medical School, Israel.
Loewenstein
A
A
Lazar
M
M
D000328:Adult; D000704:Analysis of Variance; D004596:Electroretinography / Q000187:drug effects*; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012160:Retina / Q000187:drug effects* / Q000503:physiopathology; D012559:Schizophrenia / Q000188:drug therapy; D013881:Thioridazine / Q000009:adverse effects*; D014786:Vision Disorders / Q000139:chemically induced* / Q000503:physiopathology
D013881:Thioridazine