title: [Remote effects in cerebral infarction--123I-IMP SPECT study].
abstract: We studied the remote effects in 29 patients with middle cerebral artery territory infarction by using single photon emission computed tomography (SPECT) with N-isopropyl-p-[123I]iodoamphetamine. SPECT demonstrated a reduction in blood flow in the cerebellar hemisphere contralateral to the cerebral infarct, the cortex ipsilateral to the subcortical infarct, the visual cortex distal to the optic radiation lesion, and the thalamus ipsilateral to the cortical infarct. In addition to transient neuronal depression identified with diaschisis, our results indicated that persistent phenomena were apparently involved in these remote effects. The degenerative processes might be related to irreversible effects in remote areas. Clinical symptoms corresponding to the areas of hypoperfusion remote from infarcted lesions were not necessarily present.
authors.affiliation: Department of Geriatric Medicine, Tokyo Medical College.
authors.forename: H
authors.initials: H
authors.lastname: Hanyu
authors.forename: H
authors.initials: H
authors.lastname: Arai
authors.forename: Y
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: N
authors.initials: N
authors.lastname: Hatano
authors.forename: H
authors.initials: H
authors.lastname: Katsunuma
authors.forename: T
authors.initials: T
authors.lastname: Suzuki
mesh_terms: D000368:Aged; D000662:Amphetamines; D001921:Brain / Q000098:blood supply; D002544:Cerebral Infarction / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D020367:Iofetamine; D008297:Male; D008875:Middle Aged; D012039:Regional Blood Flow; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D000662:Amphetamines; D007457:Iodine Radioisotopes; D020367:Iofetamine