title: Pulmonary infiltrates and fever induced by isoniazid.
abstract: An 88 year old woman with bacteriologically confirmed pulmonary tuberculosis was first treated with isoniazid, rifampicin and pyrazinamide. Two weeks later she developed pulmonary infiltrates with fever. A drug-induced reaction was suspected but the reaction recurred three times until isoniazid was identified as the cause. The reaction became worse each time, finally being nearly fatal.
authors.affiliation: Department of Diseases of the Chest, University Central Hospital of Turku, Preitilä, Finland.
authors.forename: E R
authors.initials: ER
authors.lastname: Salomaa
authors.forename: E L
authors.initials: EL
authors.lastname: Ruokonen
authors.forename: K
authors.initials: K
authors.lastname: Tevola
authors.forename: E
authors.initials: E
authors.lastname: Tala
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001424:Bacterial Infections / Q000175:diagnosis; D003937:Diagnosis, Differential; D004342:Drug Hypersensitivity / Q000175:diagnosis; D005260:Female; D005334:Fever / Q000139:chemically induced*; D006801:Humans; D007538:Isoniazid / Q000009:adverse effects*; D011658:Pulmonary Fibrosis / Q000139:chemically induced*
chemical_list: D007538:Isoniazid