Water intoxication and rhabdomyolysis.
A 44-year-old woman was admitted because of stupor. She had consumed 3 liters of water due to thirst after drinking alcohol. Laboratory findings on admission revealed marked hyponatremia (sodium: 115 mEq/l). She was diagnosed as having water intoxication. She recovered from her hyponatremia upon excretion of a large amount of hypotonic urine. Subsequently, however, her serum creatine phosphokinase was markedly elevated at 28,650 IU/l, and her serum myoglobin reached 2,760 ng/ml. The relationship between the occurrence of hyponatremia secondary to water intoxication and rhabdomyolysis was suggested.
Tomiyama
J
J
Department of Internal Medicine, Bokuto Metropolitan Hospital, Tokyo, Japan.
Kametani
H
H
Kumagai
Y
Y
Adachi
Y
Y
Tohri
K
K
D000328:Adult; D003402:Creatine Kinase / Q000097:blood / Q000378:metabolism; D005260:Female; D006760:Hospitalization; D006801:Humans; D007010:Hyponatremia / Q000150:complications* / Q000000981:diagnostic imaging; D009211:Myoglobin / Q000378:metabolism; D011877:Radionuclide Imaging; D012206:Rhabdomyolysis / Q000000981:diagnostic imaging / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D014869:Water Intoxication / Q000150:complications* / Q000000981:diagnostic imaging
D009211:Myoglobin; D003402:Creatine Kinase