[Prenatal diagnosis of cystic fibrosis based on DNA analysis].
25 families at risk of having a child with cystic fibrosis have been counselled about prenatal diagnosis by the use of linked DNA probes (xV-2c, pCS.7, Met D, Met H, pJ3.11 and KM 19). In 20 families one or more informative probes, in 3 cases only partly informative probes were found, and in 2 families there was no informative probe at all. In 9 cases prenatal diagnosis have been performed, 6 children have been born and confirmed to be free from cystic fibrosis and 3 terminations were carried out because of prenatal prediction of cystic fibrosis.
Nemeti
M
M
Debreceni Orvostudományi Egyetem, Szülészeti és Nögyógyászati Klinika.
Bolodár
A
A
Papp
Z
Z
D000028:Abortion, Induced; D003550:Cystic Fibrosis / Q000175:diagnosis / Q000235:genetics*; D005260:Female; D005817:Genetic Counseling; D005819:Genetic Markers / Q000235:genetics; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods; D011379:Prognosis
D005819:Genetic Markers
A cysticus fibrosis DNS analízisen alapuló praenatalis diagnosztikája.