title: Relief of injection pain in adults. EMLA cream for 5 minutes before venepuncture.
abstract: The effectiveness of skin anaesthesia after 5 minutes' topical application of a lignocaine-prilocaine cream was evaluated. One hundred and twenty patients estimated the pain of antecubital venepuncture both on a linear scale and verbally after use of the cream for either 5 or 60 minutes, a placebo cream or no treatment. Reported pain was significantly less after only 5 minutes of the lignocaine-prilocaine cream (p = 0.002). The cream can be used to relieve the pain of all routine injections.
authors.affiliation: Department of Anaesthetics, Royal West Sussex Hospital, St Richard's, Chichester.
authors.forename: M R
authors.initials: MR
authors.lastname: Nott
authors.forename: J L
authors.initials: JL
authors.lastname: Peacock
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000779:Anesthetics, Local / Q000008:administration & dosage*; D001815:Bloodletting / Q000009:adverse effects*; D004338:Drug Combinations; D005260:Female; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage*; D000077442:Lidocaine, Prilocaine Drug Combination; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000517:prevention & control*; D011318:Prilocaine / Q000008:administration & dosage*; D013997:Time Factors
chemical_list: D000779:Anesthetics, Local; D004338:Drug Combinations; D000077442:Lidocaine, Prilocaine Drug Combination; D011318:Prilocaine; D008012:Lidocaine