MRSA meningitis in postoperative patients. Report of 4 cases.
Four cases of postoperative meningitis caused by methicillin-resistant Staphylococcus aureus (MRSA) are reported together with a review of the literature. These 4 cases were treated successfully by intravenous administration of minomycin, fosfomycin, and cefmetazole. Factors associated with the development of meningitis included multiple craniotomies, the presence of ventricular drainage or a ventriculo-peritoneal shunt, and irradiation.
Sakamoto
T
T
Department of Laboratory Medicine, Akita University Hospital.
Kikuchi
K
K
Mineura
K
K
Kowada
M
M
Nakagomi
O
O
D000328:Adult; D015311:Cefmetazole / Q000008:administration & dosage; D004359:Drug Therapy, Combination / Q000008:administration & dosage; D005578:Fosfomycin / Q000008:administration & dosage; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008581:Meningitis / Q000188:drug therapy / Q000382:microbiology*; D016106:Methicillin Resistance; D008875:Middle Aged; D008911:Minocycline / Q000008:administration & dosage; D011183:Postoperative Complications; D013203:Staphylococcal Infections; D013211:Staphylococcus aureus
D005578:Fosfomycin; D015311:Cefmetazole; D008911:Minocycline