title: [A case of chronic subdural hematoma associated with idiopathic thrombocytopenic purpura (ITP)].
abstract: A 41-year-old male was admitted to our service with right occipital pain as his chief complaint. CT and MRI examinations revealed bilateral chronic subdural hematomas. The patient had also been affected with ITP since the age of 28. Since emergency operation was thought to be dangerous, he was transferred to Tokushima University Hospital, and treated preoperatively by administration of steroids and a large dose of immunoglobulin. When his platelet count had returned to 146,000/mm3, evacuation of the hematoma through burr holes was performed successfully under local anesthesia. The postoperative course was uneventful. So far as we have been able to find in the literature, only 3 cases of ITP complicated by chronic subdural hematoma have been reported. The characteristic clinical feature of these 4 cases including our own case was noted as the absence of a history of trauma. However, the etiological relationship between ITP and chronic subdural hematoma was controversial. Occurrence of chronic subdural hematoma in patients with ITP and in patients under hemodialyzer treatment is very rare. However, intracerebral hemorrhages are rather common among such patients. So it was suggested that the tendency to bleeding among patients with ITP, and among hemodialyzer patients may contribute little as an etiological factor in the evolution of chronic subdural hematoma.
authors.affiliation: Department of Neurosurgery, University of Tokushima.
authors.forename: A
authors.initials: A
authors.lastname: Sebe
authors.forename: T
authors.initials: T
authors.lastname: Ohshima
authors.forename: D
authors.initials: D
authors.lastname: Ebisudani
authors.forename: H
authors.initials: H
authors.lastname: Oka
authors.forename: K
authors.initials: K
authors.lastname: Matsumoto
authors.forename: S
authors.initials: S
authors.lastname: Yoshizima
mesh_terms: D000328:Adult; D002908:Chronic Disease; D006408:Hematoma, Subdural / Q000150:complications* / Q000601:surgery; D006801:Humans; D007116:Immunization, Passive; D008297:Male; D010976:Platelet Count / Q000187:drug effects; D011239:Prednisolone / Q000627:therapeutic use; D011300:Preoperative Care; D011696:Purpura, Thrombocytopenic / Q000097:blood / Q000150:complications* / Q000628:therapy
chemical_list: D011239:Prednisolone