[Environmental interstitial pneumonia caused by asbestos. Study of a Turkish family exposed to tremolite].
Environmental exposure to asbestos, as observed in Anatolia (Turkey), usually results in pleural pathology (plaques and mesothelioma). We report the case of a 50-year old woman who, until the age of 50, had lived in Eregli, central Anatolia, a region where inhalation of environmental asbestos is responsible for a high prevalence of pleural diseases. Radiology showed diffuse interstitial pneumonia without pleural involvement. Bronchoalveolar lavage brought back asbestos bodies (AB) in concentrations of 4,250 per millilitre. All were made of tremolite, a non-commercial variety of asbestos. The patient's family was investigated by chest radiography and search for AB in sputum. The husband, who came from the same town as his wife and had been exposed until the age of 45, had the classical response with bilateral pleural thickening but no parenchymal abnormalities; 2 AB were found in his sputum. The 3 sons, exposed for 10, 13 and 20 years respectively, had normal radiograms and no AB in their sputum, except for the older (3 AB) who had been exposed for 20 years. These cases illustrate the importance of environmental exposure to asbestos which may produce lesions similar to those observed in industrial exposure. Only mineralogical examinations can determine whether the asbestos is environmental or industrial.
Larrouy
C
C
Services de Pneumologie et d'Anatomopathologie, Centre hospitalier intercommunal, Montfermeil.
Tandjaoui-Lambiotte
H
H
Mellat
M
M
Fabre
C
C
Defrejacques
C
C
Adotti
F
F
Piquet
J
J
D001194:Asbestos / Q000009:adverse effects*; D017636:Asbestos, Amphibole; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008875:Middle Aged; D010375:Pedigree; D011658:Pulmonary Fibrosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000235:genetics; D012824:Silicic Acid / Q000009:adverse effects; D014057:Tomography, X-Ray Computed; D014421:Turkey
D017636:Asbestos, Amphibole; D001194:Asbestos; D012824:Silicic Acid; C005846:tremolite
Pneumopathie interstitielle environnementale à l'amiante. Etude d'une famille turque exposée à la trémolite.