title: Three-dimensional reconstruction of stenosed coronary artery segments with assessment of the flow impedance.
abstract: In this paper preliminary results of a study about the diagnostic benefits of 3D visualization and quantitation of stenosed coronary artery segments are presented. As is well known, even biplane angiographic images do not provide enough information for binary reconstruction. Therefore, a priori information about the slice to be reconstructed must be incorporated into the reconstruction algorithm. One approach is to assume a circular cross-section of the coronary artery. Hence, the diameter is estimated from the contours of the vessels in both projections. Another approach is to search for a solution of the reconstruction problem close to the previously reconstructed adjacent slice. In this paper we follow the first method based on contour information. The reconstructed coronary segment is visualized in three dimensions. Based on the obtained geometry of the obstruction the pertinent blood flow impedance is estimated on the basis of fluid dynamic principles. The results of applying the reconstruction algorithms to clinical coronary biplane exposure are presented with an indication of the assessed flow impedance.
authors.affiliation: Philips Medical Systems, Best, The Netherlands.
authors.forename: A A
authors.initials: AA
authors.lastname: Hulzbosch
authors.forename: C H
authors.initials: CH
authors.lastname: Slump
authors.forename: M A
authors.initials: MA
authors.lastname: Viergever
mesh_terms: D000792:Angiography; D003251:Constriction, Pathologic / Q000000981:diagnostic imaging; D017023:Coronary Angiography; D003326:Coronary Circulation; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003331:Coronary Vessels / Q000473:pathology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008955:Models, Cardiovascular