title: In vitro fertilization and development of one of two human oocytes with fused zonae pellucidae: case report.
abstract: This report describes a pair of human oocytes of differing maturities but fused at the zona pellucida, believed to have originated from a binovular follicle. After insemination in vitro, one oocyte fertilized and developed into an expanded blastocyst, whereas the other, which contained a germinal vesicle, degenerated. A biopsy was aspirated from the blastocyst, which subsequently re-expanded but did not hatch.
authors.affiliation: Bourn Hall Clinic, Bourn, Cambridge, United Kingdom.
authors.forename: G M
authors.initials: GM
authors.lastname: Hartshorne
authors.forename: M
authors.initials: M
authors.lastname: Blayney
authors.forename: H
authors.initials: H
authors.lastname: Dyson
authors.forename: K
authors.initials: K
authors.lastname: Elder
mesh_terms: D000328:Adult; D002450:Cell Communication / Q000502:physiology; D002678:Chimera; D005314:Embryonic and Fetal Development / Q000502:physiology*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D009030:Mosaicism / Q000502:physiology; D009865:Oocytes / Q000166:cytology / Q000502:physiology*; D015044:Zona Pellucida / Q000502:physiology*