[Bone replacement using demineralized allogeneic bone in animal experiments].
The implantation of bone matrix in muscle bag or trepanation defects of rats with greatest reproducibility will induce osteogenesis and defect healing. The phenomenon of osteo-induction was possible to obtain only in first steps in higher developed mammals. Investigations in nude rats have shown a clear difference in biologic reaction on the matrix of various species. The osteo-regeneration in replacement weak defect of ulnar bone in dogs showed a massive greater reactivity of autogenous spongiosa, whereas bank spongiosa and bone matrix produced not more new bone as the control. An increase of osteoinductive matrix potency is a supposition for practical use in case of severe bone defects.
Schwarz
N
N
Ludwig-Blotzmann-Institut für Experimentelle und Klinische Traumatologie, Wien, Osterreich.
Redl
H
H
Schlag
G
G
D000818:Animals; D001857:Bone Matrix / Q000637:transplantation*; D016025:Bone Transplantation / Q000379:methods*; D009132:Muscles / Q000601:surgery; D010012:Osteogenesis / Q000502:physiology*; D051381:Rats; D011919:Rats, Inbred Strains; D014945:Wound Healing
Knochenersatz mit demineralisiertem allogenen Knochen im Tierexperiment.