[Interhemispherical study of the activities of aminopeptidases, lactate dehydrogenase and glutamate-oxaloacetate transaminase in the rat brain].
Aminopeptidase activity has been assayed from both soluble and membrane bound fractions in eleven regions of the left and right hemispheres of the rat brain, using L-leucine-2-naphthylamide as substrate. Two other metabolic enzymes, lactate dehydrogenase and glutamate-oxalacetate aminotransferase activities were simultaneously determined in the same areas. When individual zones of the left hemisphere were compared with its corresponding right zones, soluble aminopeptidase activities were significantly higher in left frontal cortex and left hypothalamus than in right frontal cortex and right hypothalamus, respectively. No other significant differences were found neither in the remaining areas nor for the other enzymatic activities between both brain hemispheres.
Ramírez
M
M
Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Universidad de Granada.
Iribar
C
C
Gil
M T
MT
García
J R
JR
Alba
F
F
D000626:Aminopeptidases / Q000032:analysis*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000032:analysis*; D001921:Brain / Q000201:enzymology*; D007839:Functional Laterality; D007770:L-Lactate Dehydrogenase / Q000032:analysis*; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
D007770:L-Lactate Dehydrogenase; D001219:Aspartate Aminotransferases; D000626:Aminopeptidases
Estudio interhemisférico de actividad de aminopeptidasas, lactato deshidrogenasa y glutamato-oxalacetato transaminasa en cerebro de rata.