title: [Effect of postoperative hypertonic sodium infusion in the patients with total gastrectomy for gastric cancer].
abstract: In 17 patients with gastric cancer undergoing total gastrectomy, the effect of postoperative hypertonic sodium infusion were studied. The subjects were divided into 2 groups by concentration in the postoperative infusions. Group 1(Na group): over 5.0 mEq/Kg/day of sodium were infused in the postoperative days (POD). (End of operation to POD-4), Group 2 (Control group): 2.0-2.5 mEq/Kg/day of sodium (End of Op. to POD-1), 1.5-2.0 mEq/Kg/day (POD-2-4). 2.0-2.5 mEq/Kg/day were infused after POD-5 in both groups. In the Na group, NAG-Index, FENa and BUN were higher than those of control group. And cumulative primary Na balance (from end of operation to POD-5) indicated positive balance in Na group, and negative in control group. Furthermore, the cumulative infused sodium dose correlated with cumulated urinary sodium dose, potassium dose and cumulative NAG dose (from end of operation to POD-5). Significant difference was observed between two groups in urinary nitrogen. These findings suggest that the sodium dose in the postoperative infusion were suitable with 2.0-2.5 mEq/Kg/day.
authors.affiliation: Department of Surgery, Kansai Medical University, Osaka, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Kojima
authors.forename: Y
authors.initials: Y
authors.lastname: Hiramatsu
authors.forename: A
authors.initials: A
authors.lastname: Nakagawa
authors.forename: T
authors.initials: T
authors.lastname: Sanada
authors.forename: Y
authors.initials: Y
authors.lastname: Nakane
authors.forename: K
authors.initials: K
authors.lastname: Hioki
authors.forename: M
authors.initials: M
authors.lastname: Yamamoto
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005743:Gastrectomy / Q000379:methods; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009318:Natriuresis; D011182:Postoperative Care; D012462:Saline Solution, Hypertonic / Q000008:administration & dosage* / Q000627:therapeutic use; D013274:Stomach Neoplasms / Q000378:metabolism / Q000601:surgery*; D014882:Water-Electrolyte Balance
chemical_list: D012462:Saline Solution, Hypertonic