Azathioprine-related cholestatic jaundice in heart transplant patients.
Azathioprine is an immunosuppressive drug occasionally indicted as the cause of some episodes of acute cholestasis. The case described confirms the possibility of acute, severe, and reversible cholestatic hepatopathy of iatrogenic (toxic rather than idiosyncratic) origin.
Perini
G P
GP
Division of Cardiovascular Rehabilitation and Gastroenterology, University of Verona, Italy.
Bonadiman
C
C
Fraccaroli
G P
GP
Vantini
I
I
D000328:Adult; D001379:Azathioprine / Q000009:adverse effects* / Q000627:therapeutic use; D002779:Cholestasis / Q000139:chemically induced*; D003524:Cyclosporins / Q000627:therapeutic use; D016027:Heart Transplantation; D006801:Humans; D007165:Immunosuppression Therapy; D008297:Male; D011241:Prednisone / Q000627:therapeutic use
D003524:Cyclosporins; D001379:Azathioprine; D011241:Prednisone