title: [Gastric cancer presenting a variety of macroscopic and histopathological findings].
abstract: A 68-year-old man was admitted to hospital because of nausea and vomiting. Examination of the upper digestive tract led to a total gastrectomy. A histopathological examination revealed a Borrmann type 3 advanced cancer in the prepyloric antrum that showed a moderately differentiated adenocarcinoma. Found on the anterior wall of the middle corpus was an advanced cancer, mimicking a type IIc early cancer, that was poorly differentiated with dispersed signet ring cells. Between these two advanced cancers, another superficially extended cancer, consisting of a type IIa and IIb early cancer, was found. The type IIa cancer, located on the posterior wall of the angle, was a papillary adenocarcinoma and the type IIb cancer on the lesser curvature of the antrum was moderately differentiated. Therefore this patient displayed not only a type IIa and a type IIb cancer, but also a Borrmann type 3 cancer and an advanced cancer, mimicking type IIc, that were linked into one large lesion. Although the present case was not determined as being a multiple gastric cancer, it suggests the likelihood of a multicentric generation, growth, and extension of synchronous multiple cancers, in view of the variety of macroscopic and histopathological findings presented.
authors.affiliation: Dept. of Internal Med., Toyonaka Municipal Hospital.
authors.forename: K
authors.initials: K
authors.lastname: Nakajima
authors.forename: M
authors.initials: M
authors.lastname: Takami
authors.forename: M
authors.initials: M
authors.lastname: Hanada
authors.forename: T
authors.initials: T
authors.lastname: Nakajima
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000231:Adenocarcinoma, Papillary / Q000473:pathology*; D000236:Adenoma / Q000473:pathology; D000368:Aged; D003937:Diagnosis, Differential; D005773:Gastroscopy; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D009378:Neoplasms, Multiple Primary; D011706:Pyloric Antrum / Q000473:pathology; D013274:Stomach Neoplasms / Q000473:pathology*