title: Development of hormone refractory tumors: adaption versus clonal selection.
authors.affiliation: Urologische Abteilung, Marienhospital, Universität Bochum, Herne, FRG.
authors.forename: H
authors.initials: H
authors.lastname: Schulze
authors.forename: J T
authors.initials: JT
authors.lastname: Isaacs
mesh_terms: D000222:Adaptation, Physiological; D000726:Androgen Antagonists / Q000627:therapeutic use*; D000818:Animals; D004351:Drug Resistance; D006801:Humans; D008297:Male; D009376:Neoplasms, Hormone-Dependent / Q000628:therapy*; D009919:Orchiectomy; D011471:Prostatic Neoplasms / Q000628:therapy*
chemical_list: D000726:Androgen Antagonists