title: The effects of lying position on ventricular volume in congenital absence of the pericardium.
abstract: In patients with congenital absence of the left pericardium, the heart is supported by the existing right pericardium in the right lateral position, while it is not in the left lateral position. To investigate the change in ventricular size resulting from postural change, seven patients with this malformation were examined. Ventricular volumes were calculated by computed tomography, integrating areas of computed tomographic cross sections measured at 1 cm intervals from the cardiac apex to the aortic arch. In the right lateral position, right ventricular (RV) and left ventricular (LV) volumes were no different from those of five control subjects. With a change in the lying position to the left, the increase in the ventricular volume was significantly greater than that in the control subjects (35 +/- 11 versus 3 +/- 3 ml in the right ventricle and 15 +/- 13 versus 3 +/- 8 ml in the left ventricle). The increases in RV and LV end-diastolic pressure, however, were almost the same as those in the 11 control subjects. It is concluded that the cardiac ventricle, especially the right ventricle, dilates significantly with a small increase in preload in patients with congenital absence of the pericardium. It may be a clue for clarifying the ventricular distensibility being freed from physiologic restraint of the pericardium for a long period.
authors.affiliation: National Cardiovascular Center, Research Institute and Hospital, Osaka, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Beppu
authors.forename: H
authors.initials: H
authors.lastname: Naito
authors.forename: M
authors.initials: M
authors.lastname: Matsuhisa
authors.forename: K
authors.initials: K
authors.lastname: Miyatake
authors.forename: Y
authors.initials: Y
authors.lastname: Nimura
mesh_terms: D000328:Adult; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010496:Pericardium / Q000002:abnormalities*; D011187:Posture / Q000502:physiology*; D014057:Tomography, X-Ray Computed