[The parthenogenetic activation under the action of cycloheximide of mouse oocytes matured in vivo].
Treatment of mouse oocytes matured in vivo by cycloheximide at a concentration 25 micrograms/ml for 2 h induced female pronucleus formation. In all activated oocytes the formation of the female nucleus was completed 5-6 h after the beginning of cycloheximide treatment. When cycloheximide concentration was decreased down to 5 micrograms/ml, its effect was detected 1 h later as compared with that at a concentration of 25 micrograms/ml.
Khamidov
D Kh
DKh
Koval'
T Iu
TIu
Shaiunusova
D
D
Goncharova
E
E
D000818:Animals; D002467:Cell Nucleus / Q000187:drug effects; D003513:Cycloheximide / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006238:Haploidy; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009865:Oocytes / Q000187:drug effects* / Q000254:growth & development; D010312:Parthenogenesis / Q000187:drug effects*; D013268:Stimulation, Chemical; D013997:Time Factors
D003513:Cycloheximide
Partenogeneticheskaia aktivatsiia sozrevshikh in vivo ootsitov myshi pod deĭstviem tsiklogeksimida.