title: [Problems of the preparation and control of properties of sterile drug-containing liposomes].
abstract: The techniques employed to produce drug-containing liposomes and to control the disperse composition of the included preparation are discussed. The method of cryoradiation sterilization of liposomes containing different types of drugs is detailed. The applications of the described methodologies for obtaining the optimal technological parameters of liposome production are exemplified.
authors.forename: V I
authors.initials: VI
authors.lastname: Trofimov
authors.forename: M M
authors.initials: MM
authors.lastname: Nisnevich
mesh_terms: D004337:Drug Carriers; D004355:Drug Stability; D004356:Drug Storage / Q000379:methods; D004358:Drug Therapy / Q000379:methods*; D006801:Humans; D008081:Liposomes / Q000138:chemical synthesis / Q000494:pharmacology / Q000592:standards / Q000627:therapeutic use*; D004364:Pharmaceutical Preparations / Q000008:administration & dosage*; D011786:Quality Control; D013242:Sterilization / Q000379:methods; D013678:Technology, Pharmaceutical / Q000379:methods*; D014586:USSR
chemical_list: D004337:Drug Carriers; D008081:Liposomes; D004364:Pharmaceutical Preparations
vernacular_title: Voprosy polucheniia i kontrolia svoĭstv steril'nykh liposom s lekarstvennymi preparatami.