Non-contact acoustic method for the simultaneous measurement of thickness and acoustic properties of biological tissues.
The frequency dependence of the magnitude and phase shift of reflected waves from a thin tissue specimen has been found to yield characteristic patterns as a function of the specimen thickness. By analysis of those characteristic patterns, the specimen thickness can be determined so that the attenuation constant and the sound speed can be obtained by a non-contact procedure. The method is demonstrated in the frequency range 100 MHz to 200 MHz, using a scanning acoustic microscope and approximately 10 microns thick myocardial tissue samples of human origin, one paraffin embedded.
Okawai
H
H
Research Institute for Chest Diseases and Cancer, Tohoku University, Sendai, Japan.
Tanaka
M
M
Dunn
F
F
D000162:Acoustics / Q000295:instrumentation*; D004452:Echocardiography; D006801:Humans; D008853:Microscopy / Q000295:instrumentation / Q000379:methods*; D009206:Myocardium / Q000473:pathology