title: [Pathogenesis and clinical aspects of atopic dermatitis].
abstract: Atopic dermatitis (a. D.) is a chronically relapsing inflammatory disease of the skin caused by a genetically transmitted hypersensitivity to environmental substances. Its pathogenesis is complex and multifactorial: heredity of atopic constitution, disturbances of humoral (hyperimmunoglobulinemia-E) and cellular (defect of suppressor-T-cells) immunity, abnormal vascular reactions and abnormal skin functions. A. D. shows different forms in different age groups: Eczema infantum in infancy, Eczema flexurarum in childhood and Neurodermatitis disseminata and pruriginosa while and after puberty. Typically for all forms is a pruritus and the status neurodermiticus. The healing of a. D. is spontaneously possible at any time, but not predictable for a special case.
authors.affiliation: Gottfried von Preyer'sches Kinderspital der Stadt Wien.
authors.forename: W
authors.initials: W
authors.lastname: Stögmann
mesh_terms: D000917:Antibody Formation; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000235:genetics / Q000276:immunology*; D004485:Eczema / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D007223:Infant; D009450:Neurodermatitis / Q000276:immunology
vernacular_title: Pathogenese und Klinik der atopischen Dermatitis.