title: Neonatal sepsis due to Streptococcus pneumoniae.
abstract: A 20-year-old primigravida in the 33rd week of gestation was delivered of a girl weighing 1,790 g 23 h after spontaneous rupture of the membranes. 13 h after birth, the child showed signs of shock. Cultures of blood, conjunctiva and nasopharyngeal aspirate grew Streptococcus pneumoniae of serotype 11. Cultures from the mother's cervix and from the placenta and membranes also grew S. pneumoniae of the same serotype. The infant responded well to ampicillin and netilmicin. The early-onset pneumococcal septicemic cases reported over the last 20 years are reviewed.
authors.affiliation: Department of Bacteriology, University Hospital St Rafaël, Leuven, Belgium.
authors.forename: J
authors.initials: J
authors.lastname: Jacobs
authors.forename: K
authors.initials: K
authors.lastname: Garmyn
authors.forename: J
authors.initials: J
authors.lastname: Verhaegen
authors.forename: H
authors.initials: H
authors.lastname: Devlieger
authors.forename: E
authors.initials: E
authors.lastname: Eggermont
mesh_terms: D000328:Adult; D000667:Ampicillin / Q000627:therapeutic use; D002584:Cervix Uteri / Q000382:microbiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D009428:Netilmicin / Q000627:therapeutic use; D010920:Placenta / Q000382:microbiology; D011008:Pneumococcal Infections / Q000188:drug therapy / Q000382:microbiology*; D011247:Pregnancy; D012307:Risk Factors; D018805:Sepsis / Q000188:drug therapy / Q000382:microbiology*; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification / Q000302:isolation & purification*
chemical_list: D009428:Netilmicin; D000667:Ampicillin