Lactate movements in the term human placenta in situ.
Movements of lactate through the human placenta in situ were derived from maternal and fetal blood sampling performed under conditions that approximate as closely as possible the normal fetal metabolic state. It is reported that, at the end of pregnancy, the human fetus produces lactate which is transferred to the placenta. The actuality of this lactate transfer coupled with proton transfer is discussed taking into account the results of multiple linear regression analysis determined between the umbilical arterio-venous lactate differences and fetal and maternal lactate and proton concentrations. It is finally assumed that this lactate is partly metabolized in the placenta, the remaining part being transferred from the placenta to the mother.
Piquard
F
F
Institut de Physiologie, Faculté de Médecine, Université Louis-Pasteur, Strasbourg, France.
Schaefer
A
A
Dellenbach
P
P
Haberey
P
P
D000328:Adult; D001784:Blood Gas Analysis; D005260:Female; D005312:Fetal Blood; D005333:Fetus / Q000378:metabolism; D006801:Humans; D007773:Lactates / Q000378:metabolism*; D019344:Lactic Acid; D010920:Placenta / Q000378:metabolism*; D011247:Pregnancy; D012044:Regression Analysis
D007773:Lactates; D019344:Lactic Acid