[In vitro antifungal activity of mercurobutol].
Mercurobutol, in its commercial form, exhibits fungistatic and fungicidal activities against both yeasts: Candida albicans, C. tropicalis, Torulopsis glabrata, Pityrosporum spp., and filamentous fungi: dermatophytes, Aspergillus fumigatus, mainly saprophytic or potentially pathogenic fungi of the cutaneo-mucous flora. Minimal inhibitory concentrations on this antiseptic indicate a high susceptibility of the species tested, that could justify the enlargement of the indication of the drug to the complementary treatment of most cutaneous mycosis.
Boiron
P
P
Unité de Mycologie, Institut Pasteur, Paris, France.
D000935:Antifungal Agents / Q000494:pharmacology*; D003883:Arthrodermataceae / Q000187:drug effects*; D001230:Aspergillus / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D066298:In Vitro Techniques; D010663:Phenylmercury Compounds / Q000494:pharmacology*; D015003:Yeasts / Q000187:drug effects*
D000935:Antifungal Agents; D010663:Phenylmercury Compounds; C066353:mercurobutol
Activité antifongique du mercurobutol in vitro.