title: [The sodium excretion behavior of anesthetized and conscious spontaneously-hypertensive (SHR) and normotensive (WKY) rats].
abstract: Urethane-anesthetized and conscious, immobilized SHR subjected to osmotic diuresis, responded to intravenous saline loading with a larger natriuresis than WKY-rats due to an increased urine sodium concentration without differences in urine flow. Blood pressure and heart rate reactions after saline loading were qualitatively different in anesthetized and conscious rats. The magnitude of these changes was larger in WKY than in SHR in both experimental groups.
authors.affiliation: Zentralinstitut für Herz-Kreislauf-Forschung, der AdW der DDR; Berlin-Buch.
authors.forename: V
authors.initials: V
authors.lastname: Gross
authors.forename: U
authors.initials: U
authors.lastname: Gnüchtel
authors.forename: G
authors.initials: G
authors.lastname: Orlow
authors.forename: E R
authors.initials: ER
authors.lastname: Martinova
mesh_terms: D000758:Anesthesia / Q000662:veterinary; D000818:Animals; D006973:Hypertension / Q000652:urine / Q000662:veterinary*; D009318:Natriuresis; D051381:Rats; D011918:Rats, Inbred SHR / Q000378:metabolism*; D011921:Rats, Inbred WKY / Q000378:metabolism*; D012376:Rodent Diseases / Q000652:urine*; D014520:Urethane
chemical_list: D014520:Urethane
vernacular_title: Zum Natriumausscheidungsverhalten von narkotisierten und wachen spontan-hypertensiven (SHR) und normotensiven (WKY) Ratten.