title: Polyurethane foam-covered implants and capsular contracture: a laboratory investigation.
abstract: Experiments were conducted in rabbits comparing polyurethane foam-covered implants with otherwise identical smooth silicone gel implants. Using five objective methods of measurement of capsular contracture, no significant difference could be identified. The foam-covered implants consistently developed capsular contracture, although in most cases this was of mild degree and would not have been clinically significant. In the two foam-covered implants with hard contractures, there was no evidence of hematoma or separation of the foam.
authors.affiliation: University of Florida College of Medicine, Gainesville.
authors.forename: H H
authors.initials: HH
authors.lastname: Caffee
authors.forename: C
authors.initials: C
authors.lastname: Hathaway
mesh_terms: D000818:Animals; D001940:Breast / Q000601:surgery*; D003286:Contracture / Q000209:etiology*; D005260:Female; D005782:Gels; D011140:Polyurethanes; D011446:Prospective Studies; D019736:Prostheses and Implants; D011474:Prosthesis Design; D011817:Rabbits; D012828:Silicones
chemical_list: D005782:Gels; D011140:Polyurethanes; D012828:Silicones