Eosinophilia-myalgia syndrome (L-tryptophan-associated neuromyopathy).
Histopathologic study of skeletal muscle biopsy in a patient with eosinophilia-myalgia syndrome following L-tryptophan use showed prominent lymphocytic perineuritis, neuritis, and perimysial fasciitis. The presence of perineuritis and neuritis provides a histopathologic basis for clinical features of neuropathy in eosinophilia-myalgia syndrome and occurred in conjunction with a fasciitis or interstitial myositis that was predominantly perimysial and focally endomysial.
Turi
G K
GK
Department of Pathology, Winthrop-University Hospital, Mineola, NY 11501.
Solitare
G B
GB
James
N
N
Dicker
R
R
D001706:Biopsy; D004802:Eosinophilia / Q000139:chemically induced*; D005208:Fasciitis / Q000139:chemically induced / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009132:Muscles / Q000473:pathology; D009220:Myositis / Q000139:chemically induced* / Q000473:pathology / Q000503:physiopathology; D009443:Neuritis / Q000139:chemically induced* / Q000473:pathology; D010146:Pain / Q000139:chemically induced*; D013577:Syndrome; D014364:Tryptophan / Q000009:adverse effects*
D014364:Tryptophan