title: [The use of enterosorption in the combined therapy of patients with urolithiasis complicated by chronic kidney failure].
abstract: The results of conservative treatment of 51 patients with urolithiasis complicated by chronic renal failure in the intermittent stage have been analyzed. There were two groups of patients. The first one included 36 patients receiving enterosorption in addition to routine multimodality treatment. The second group was made up of 15 patients who did not undergo enterosorption which consisted in oral application of SKH-1K coal in a dose of 10 to 15 g 3 times a day 1.5 h after meal for 10 days. The treatment efficacy was judged from the patients' general health status, central hemodynamics (cardiac index and peripheral vascular resistance), the level of azotemia, and the content of medium-sized molecules. As shown by the data obtained, the multimodality treatment coupled with enterosorption produced an appreciable improvement of the patients' health status, reduction of the signs of intoxication, while the level of medium-sized molecules and creatinine reached the control. The hypokinetic circulatory syndrome seen before the treatment disappeared. At the same time the second group patients retained the high level of azotemia, whereas the content of medium-sized molecules remained increased. Besides, they demonstrated the hypokinetic circulatory syndrome. It is thus recommended that enterosorption be applied to the treatment of patients with chronic renal failure.
authors.forename: A I
authors.initials: AI
authors.lastname: Neĭmark
mesh_terms: D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D016061:Enterosorption / Q000379:methods; D006439:Hemodynamics; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D008970:Molecular Weight; D009584:Nitrogen / Q000097:blood; D010455:Peptides / Q000097:blood; D014545:Urinary Calculi / Q000097:blood / Q000150:complications / Q000503:physiopathology / Q000628:therapy*
chemical_list: D010455:Peptides; D009584:Nitrogen
vernacular_title: Primenenie énterosorbtsii v kompleksnoĭ terapii bol'nykh mochekamennoĭ bolezn'iu, oslozhnennoĭ khronicheskoĭ pochechnoĭ neodstatochnost'iu.