Successful pregnancy after ZIFT in a patient with congenital cervical atresia.
We report the third patient with a successful pregnancy following operative correction of congenital cervical atresia. The pregnancy was achieved through zygote intrafallopian transfer (ZIFT). Although stenosis of the newly formed cervical canal causes considerable morbidity, therapy should be aimed at the creation of a conduit for menstrual blood and for possible future pregnancy. New techniques in assisted reproduction such as in vitro fertilization-embryo transfer, gamete intrafallopian transfer, and ZIFT increase the chances of pregnancy in patients with congenital cervical atresia. A hysterectomy, as advocated until very recently, should not, in our opinion, be the first treatment of choice.
Thijssen
R F
RF
Department of Obstetrics and Gynecology, St. Radboud University Hospital, Nijmegen, The Netherlands.
Hollanders
J M
JM
Willemsen
W N
WN
van der Heyden
P M
PM
van Dongen
P W
PW
Rolland
R
R
D000293:Adolescent; D002584:Cervix Uteri / Q000002:abnormalities* / Q000601:surgery; D004624:Embryo Transfer; D005260:Female; D005500:Follow-Up Studies; D015181:Gamete Intrafallopian Transfer; D006801:Humans; D011247:Pregnancy; D015053:Zygote / Q000637:transplantation*