[Angiotensin mechanism of auriculo-acupuncture dental analgesia].
In unanaesthetized rabbits auriculo-acupuncture electrostimulation with frequency of 15 Hz decreased the amplitude of somatosensory EP second component in response to the tooth pulp electrostimulation which was blocked by intravenous injection of naloxone but not by intraventricular injection of saralasin. The same effect of auriculo-acupuncture electrostimulation with frequency 100 Hz was blocked by saralasin, was increased by angiotensin II, was diminished by methysergide but wasn't changed by naloxone. It's suggested that there is angiotensinergic antinociceptive mechanism of dental pain which is activated by auriculo-acupuncture electrostimulation with frequency 100 Hz.
Kaliuzhnyĭ
L V
LV
Fedoseeva
O V
OV
D015667:Acupuncture Analgesia; D000766:Anesthesia, Dental; D000804:Angiotensin II / Q000494:pharmacology*; D000818:Animals; D003782:Dental Pulp / Q000187:drug effects; D005071:Evoked Potentials; D008297:Male; D008784:Methysergide / Q000494:pharmacology; D009270:Naloxone / Q000494:pharmacology; D011817:Rabbits; D012504:Saralasin / Q000494:pharmacology; D013003:Somatosensory Cortex / Q000187:drug effects / Q000502:physiology*
D000804:Angiotensin II; D009270:Naloxone; D012504:Saralasin; D008784:Methysergide
Angiotenzinovyĭ mekhanizm aurikulo-akupunkturnoĭ dental'noĭ analgezii.