Quantitative analysis of trace elements in human clear cell carcinoma of the kidney by energy-dispersive X-ray fluorescence.
In a case-control study, 20 cases of renal cell carcinoma (RCC) were analyzed by energy-dispersive X-ray fluorescence in order to establish the concentration of Fe, Cu, Zn and Cd. Patients with RCC were examined and compared with 7 controls from selected autopsies. A significant decrease in Cd and Zn concentration was found in the neoplastic tissue in all cases. In contrast, no significant decrease in Cu concentration was detected in our cases.
Fassina
A S
AS
Institute of Pathology, University of Padua, Italy.
Calliari
I
I
Sangiorgio
A
A
Rossato
M
M
Ramigni
M
M
Dal Bianco
M
M
Pagano
F
F
D000368:Aged; D002104:Cadmium / Q000032:analysis; D002292:Carcinoma, Renal Cell / Q000737:chemistry*; D003300:Copper / Q000032:analysis; D005260:Female; D006801:Humans; D007501:Iron / Q000032:analysis; D007680:Kidney Neoplasms / Q000737:chemistry*; D008297:Male; D008875:Middle Aged; D013052:Spectrometry, X-Ray Emission; D014131:Trace Elements / Q000032:analysis*; D015032:Zinc / Q000032:analysis
D014131:Trace Elements; D002104:Cadmium; D003300:Copper; D007501:Iron; D015032:Zinc