title: The prophylactic use of octreotide in a patient with ovarian carcinoid and valvular heart disease.
abstract: This case report describes the use of octreotide, a long-acting somatostatin analogue, in the management of a patient with an ovarian carcinoid tumour and severe cardiac valvular disease. This patient underwent laparotomy and tumour resection without complication. Anaesthesia was induced with midazolam, fentanyl, and vecuronium, and maintained with isoflurane as well as additional fentanyl and vecuronium. However, we feel that it was the use of octreotide that prevented a life-threatening crisis intraoperatively, and recommend its use in patients with carcinoid syndrome undergoing anaesthesia and surgery.
authors.affiliation: Department of Anaesthesia, University Hospital, University of Western Ontario, London.
authors.forename: J T
authors.initials: JT
authors.lastname: Watson
authors.forename: N H
authors.initials: NH
authors.lastname: Badner
authors.forename: M J
authors.initials: MJ
authors.lastname: Ali
mesh_terms: D000769:Anesthesia, Inhalation; D000771:Anesthesia, Intravenous; D002276:Carcinoid Tumor / Q000150:complications / Q000601:surgery*; D005260:Female; D006349:Heart Valve Diseases / Q000150:complications*; D006801:Humans; D007431:Intraoperative Complications / Q000517:prevention & control; D008875:Middle Aged; D015282:Octreotide / Q000627:therapeutic use*; D010051:Ovarian Neoplasms / Q000150:complications / Q000601:surgery*; D011292:Premedication; D011899:Ranitidine / Q000627:therapeutic use
chemical_list: D011899:Ranitidine; D015282:Octreotide