title: [Autologous bone marrow transplantation in children--experience with neuroblastoma].
abstract: Autologous bone marrow transplantation permits the use of greatly intensified cytoreductive therapy for cancer. Since 1983 seven children with disseminated neuroblastoma (stage IV) were treated by this method. Five were treated in first, and one in second complete remission; one child was in partial remission. Tumor cell purging of the marrow inoculum was performed in five cases. All children had engraftment and were discharged from hospital free of disease. Relapse was observed in three children within two years. Four children remain healthy at follow-up 5-77 months after autotransplantation. We describe and discuss indications, methods, side effects and results.
authors.affiliation: Barneklinikken, Rikshospitalet, Oslo.
authors.forename: I
authors.initials: I
authors.lastname: Storm-Mathisen
authors.forename: A
authors.initials: A
authors.lastname: Glomstein
authors.forename: S O
authors.initials: SO
authors.lastname: Lie
authors.forename: D
authors.initials: D
authors.lastname: Albrechtsen
authors.forename: T
authors.initials: T
authors.lastname: Monclair
authors.forename: G
authors.initials: G
authors.lastname: Kvalheim
authors.forename: A B
authors.initials: AB
authors.lastname: Jacobsen
mesh_terms: D000008:Abdominal Neoplasms / Q000628:therapy*; D000970:Antineoplastic Agents / Q000627:therapeutic use; D016026:Bone Marrow Transplantation / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D009447:Neuroblastoma / Q000628:therapy*; D012074:Remission Induction; D014182:Transplantation, Autologous / Q000379:methods
chemical_list: D000970:Antineoplastic Agents
vernacular_title: Autolog beinmargstransplantasjon hos barn--erfaringer ved neuroblastom.