[Pregnancy in diabetes insipidus--a case report with review of the literature].
A 32 year old I P II G with preexisting diabetes insipidus was treated with 1-(3-mercaptopropionic acid)-8-d-arginine vasopressin (DDAVP) during pregnancy. An otherwise normal pregnancy was marked only with an excessive weight increase. A healthy girl was delivered by secondary cesarean section at term. Postoperative the mother developed a water intoxication accompanying oxytocin-infusion. During nursing the diabetes insipidus improved significantly whereby DDAVP doses could be reduced to 20-10 percent. We suppose an overreaction to endogene oxytocin with an antidiuretic effect.
Cap
R
R
Frauenklinik Kantonsspital Münsterlingen.
Lüscher
K P
KP
D000281:Administration, Intranasal; D002585:Cesarean Section; D003894:Deamino Arginine Vasopressin / Q000008:administration & dosage*; D003919:Diabetes Insipidus / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D010121:Oxytocin / Q000009:adverse effects; D011183:Postoperative Complications / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D014869:Water Intoxication / Q000139:chemically induced; D014882:Water-Electrolyte Balance / Q000187:drug effects
D010121:Oxytocin; D003894:Deamino Arginine Vasopressin
Schwangerschaft bei Diabetes Insipidus--ein Fallbericht mit Literaturübersicht.