title: [A case of Legionnaires' disease, the first case in Hokkaido Prefecture--an experience of isolation of Legionella pneumophila and identification by indirect immunofluorescence antibody method].
abstract: Although 18 cases of Legionnaires' disease have been reported in Japan, these have included none from the northern areas of Japan. The first confirmed case of Legionnaires' disease in Hokkaido district, a northern island of Japan, is reported. A 48 year-old male was admitted for fulminant pneumonia, and died the next day. Legionella pneumophila, serogroup 1, was cultured and determined from the sputum and lung tissue obtained at autopsy. Postmortem examination by means of the indirect immunofluorescent method, using group specific antisera against Legionella pneumophila as a primary antibody, revealed phagocytized bacilli in the alveoli of the lung.
authors.affiliation: Clinical Laboratory, Muroran City General Hospital.
authors.forename: K
authors.initials: K
authors.lastname: Matsuda
mesh_terms: D005455:Fluorescent Antibody Technique; D006801:Humans; D007564:Japan; D007875:Legionella / Q000302:isolation & purification*; D007877:Legionnaires' Disease / Q000382:microbiology*; D008168:Lung / Q000382:microbiology; D008297:Male; D008875:Middle Aged