An immunodominant antigen of Candida albicans shows homology to the enzyme enolase.
Antibody to an immunodominant antigen of approximately 48 kDa is found in a high proportion of patients with mucocutaneous or systemic infections of the yeast Candida albicans. A cDNA encoding part of the 48 kDa antigen has been isolated. From the deduced amino acid sequence of the cDNA clone, the 48 kDa antigen shows homology to the enzyme enolase.
Franklyn
K M
KM
Department of Medical Technology, Curtin University of Technology, Bentley, WA 6102.
Warmington
J R
JR
Ott
A K
AK
Ashman
R B
RB
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology; D000595:Amino Acid Sequence; D000818:Animals; D000946:Antigens, Fungal / Q000235:genetics / Q000276:immunology*; D001483:Base Sequence; D002176:Candida albicans / Q000235:genetics* / Q000276:immunology; D002177:Candidiasis / Q000276:immunology; D002645:Chickens; D004271:DNA, Fungal; D005260:Female; D015658:HIV Infections / Q000276:immunology; D006801:Humans; D015151:Immunoblotting; D016056:Immunodominant Epitopes / Q000235:genetics* / Q000276:immunology; D008297:Male; D008969:Molecular Sequence Data; D009132:Muscles / Q000201:enzymology; D010751:Phosphopyruvate Hydratase / Q000235:genetics*; D012441:Saccharomyces cerevisiae / Q000201:enzymology; D012689:Sequence Homology, Nucleic Acid; D014623:Vaginal Diseases / Q000276:immunology
D000946:Antigens, Fungal; D004271:DNA, Fungal; D016056:Immunodominant Epitopes; D010751:Phosphopyruvate Hydratase