[The direct stimulating effect of arginine vasotocin on the functional activity of the interrenal gland in the frog Rana temporaria].
Using radioimmunoassay it has been detected that both nonoperated and hypophysectomized, lacking endogenous ACTH, frogs injected one or three times with arginine vasotocin (5.10(-9) M/kg b. w.) show a statistically significant increase of plasma corticosterone level as compared with that in control animals and frogs injected with Ringer solution. The level of 11-hydroxycorticosteroids (fluorometric determination) in the interrenal gland decreases significantly only in animals three times injected with arginine vasotocin. It is assumed that arginine vasotocin produces a direct stimulatory effect on corticosteroid-producing cells of the frog interrenal gland.
Polenov
A L
AL
Belen'kiĭ
M A
MA
Bukovskaia
O S
OS
Elifanova
A V
AV
Kuzik
V V
VV
Smorodina
I P
IP
D015062:11-Hydroxycorticosteroids / Q000032:analysis; D000305:Adrenal Cortex Hormones / Q000097:blood; D000818:Animals; D005260:Female; D007016:Hypophysectomy; D007401:Interrenal Gland / Q000737:chemistry / Q000187:drug effects* / Q000502:physiology; D008297:Male; D011896:Rana temporaria; D013268:Stimulation, Chemical; D014668:Vasotocin / Q000494:pharmacology*
D015062:11-Hydroxycorticosteroids; D000305:Adrenal Cortex Hormones; D014668:Vasotocin
Priamoe stimuliruiushchee vliianie arginin-vazototsina na funktsional'nuiu aktivnost' interrenalovoĭ zhelezy liagushki Rana temporaria.