Cardiac dysrhythmias during nasal surgery--a comparison with lignocaine-adrenaline and prilocaine-octapressin during halothane anaesthesia.
The incidence of cardiac dysrhythmias and adequacy of haemostasis during nasal surgery under deep halothane anaesthesia were studied following nasal infiltration with 10 ml of either 1.5% lignocaine with adrenaline 1:200,000 or prilocaine 1.5% with octapressin 0.03 IU per ml. There was a significant difference in the incidence of cardiac dysrhythmias between patients given octapressin 2% and patients given adrenaline infiltration (18%) p greater than 0.01. Adequate haemostasis was observed in 84% of patients who received octapressin with no adverse effects compared to 94% of the group which received adrenaline (p greater than 0.01). We suggest for the use of lignocaine-adrenaline during halothane anaesthesia that adequate ventilation is assured, deep halothane anaesthesia given, the infiltration delayed 10 minutes after tracheal intubation, the rate of injection adjusted to 10 ml in a 10-minute period and a total dose of adrenaline does not exceed 0.6 microgram/kg.
Elhakim
M
M
Department of Anaesthesiology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Omar
N S
NS
el-Kader
A A
AA
Zowel
T
T
D000281:Administration, Intranasal; D000293:Adolescent; D000328:Adult; D000769:Anesthesia, Inhalation; D001145:Arrhythmias, Cardiac / Q000139:chemically induced*; D004347:Drug Interactions; D004837:Epinephrine / Q000008:administration & dosage*; D005259:Felypressin / Q000008:administration & dosage*; D005260:Female; D006221:Halothane; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage*; D008297:Male; D009666:Nose / Q000601:surgery*; D011318:Prilocaine / Q000008:administration & dosage*
D011318:Prilocaine; D005259:Felypressin; D008012:Lidocaine; D006221:Halothane; D004837:Epinephrine