Recurrence of acoustic neurilemoma as a malignant spindle-cell neoplasm. Case report.
A 75-year-old man presented with a right cerebellopontine angle tumor 11 months after complete macroscopic resection of a right acoustic neurilemoma. Histological examination of the recurrent tumor showed a malignant spindle-cell neoplasm with positive staining for S-100 protein. The patient had no stigmata of von Recklinghausen's disease. It is proposed that this recurrence represents progression from a benign to a malignant acoustic nerve-sheath tumor, an event that is extremely rare outside the clinicopathological context of neurofibromatosis.
McLean
C A
CA
Department of Anatomical Pathology, Royal Melbourne Hospital, Australia.
Laidlaw
J D
JD
Brownbill
D S
DS
Gonzales
M F
MF
D000368:Aged; D002277:Carcinoma / Q000473:pathology*; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D009464:Neuroma, Acoustic / Q000473:pathology* / Q000601:surgery