[The anti-implantation effects of various savine extracts on the pregnant rat].
Ether and ethyl acetate extracts obtained after savin essential oil extraction, were administered, on days 1 to 4, to pregnant rats by intragastric catheter, at doses of 0, 50 or 150 mg/Kg, to search for their possible effects on implantation. The ethyl acetate extract was not toxic. Inversely, the ether extract was responsible for a dose-dependent anti-implantation effect, thus showing that essential oil is not alone responsible for the abortive effect generally attributed to Savin.
Chamorro
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Département de Pharmacie, Ecole Nationale des Sciences Biologiques, IPN, Mexico, D.F.
Salazar
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M
Fournier
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G
Pages
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D000818:Animals; D010064:Embryo Implantation / Q000187:drug effects*; D005260:Female; D010936:Plant Extracts / Q000633:toxicity*; D011247:Pregnancy; D051381:Rats
D010936:Plant Extracts
Effets anti-implantations de différents extraits de sabine sur la rate gestante.