title: Preincubation with intravenous lipid emulsion reduces chemotactic motility of neutrophils in cord blood.
abstract: Neutrophils from cord blood of healthy term infants were isolated and incubated for 30 min with varying concentrations of intravenous lipid emulsion (ILE) solution (4, 8, 20 mg/ml). In vitro assay of chemotaxis was performed after incubation for 120 min with endotoxin-activated serum (EAS). Neutrophil random motility was unchanged after ILE incubation yet chemotactic factor (EAS)-stimulated motility was significantly reduced in a dose-related pattern.
authors.affiliation: Department of Neonatology, Assaf Harofeh Medical Center, Zerifin, Israel.
authors.forename: D
authors.initials: D
authors.lastname: Kohelet
authors.forename: S
authors.initials: S
authors.lastname: Peller
authors.forename: E
authors.initials: E
authors.lastname: Arbel
authors.forename: M
authors.initials: M
authors.lastname: Goldberg
mesh_terms: D002465:Cell Movement / Q000187:drug effects* / Q000502:physiology; D002633:Chemotaxis / Q000187:drug effects*; D005217:Fat Emulsions, Intravenous / Q000494:pharmacology*; D005312:Fetal Blood / Q000166:cytology*; D006801:Humans; D066298:In Vitro Techniques; D007231:Infant, Newborn; D009504:Neutrophils / Q000187:drug effects* / Q000502:physiology
chemical_list: D005217:Fat Emulsions, Intravenous