title: Foot ulceration and infections in elderly diabetics.
abstract: Foot lesions occur commonly among patients with diabetes, particularly the elderly and those with sensory neuropathy. Because of serious or recurrent infections and impaired healing processes, initially trivial lesions may progress to chronic nonhealing wounds, gangrene, or untreatable infections that can lead to limb amputation. Strategies to prevent amputation depend on understanding the multifactorial nature of diabetic foot disease; providing effective ongoing preventive care, including patient education; and prompt and aggressive treatment of foot lesions when they occur. The approach to treatment of infections depends on many factors, including the severity of the soft tissue infection, whether or not underlying bone or joints are involved, the types of infecting organisms, the patient's social situation, and his other medical problems. Proper diagnostic studies followed by appropriate antimicrobial therapy and local wound care can usually lead to resolution of these potentially serious infections.
authors.affiliation: Medical Service, Veterans Affairs Medical Center, Seattle, Washington.
authors.forename: B A
authors.initials: BA
authors.lastname: Lipsky
authors.forename: R E
authors.initials: RE
authors.lastname: Pecoraro
authors.forename: J H
authors.initials: JH
authors.lastname: Ahroni
mesh_terms: D000367:Age Factors; D000368:Aged; D001424:Bacterial Infections / Q000150:complications / Q000628:therapy; D048909:Diabetes Complications; D005534:Foot Diseases / Q000209:etiology* / Q000628:therapy; D006801:Humans; D010019:Osteomyelitis / Q000209:etiology / Q000628:therapy; D012883:Skin Ulcer / Q000209:etiology* / Q000628:therapy