title: Size of the fibrillar centres of the nucleoli in the supraoptic nucleus of the rat taking the Swiss cheese effect into account.
abstract: The size of the fibrillar centres (FC) in nucleoli was investigated taking the Swiss cheese effect into account. Electron microscopy was performed on the neurons of the rat supraoptic nucleus after the secretion of vasopressin had been fully suppressed by water load, after the secretion had been stimulated by water deprival and in normal rats with water ad libitum. When the secretory activity was suppressed from a normal level to approximately no activity, the size of the individual FC was doubled. Moreover, with increasing secretory activity the number of FC per cell increased.
authors.affiliation: Anatomy Department C, University of Copenhagen, Denmark.
authors.forename: L
authors.initials: L
authors.lastname: Andersen
authors.forename: N
authors.initials: N
authors.lastname: Keiding
mesh_terms: D000818:Animals; D002466:Cell Nucleolus / Q000648:ultrastructure*; D008297:Male; D008959:Models, Neurological; D009210:Myofibrils / Q000648:ultrastructure*; D051381:Rats; D013495:Supraoptic Nucleus / Q000648:ultrastructure*