title: [Esophageal motility and gastric emptying in PSS patients, correlation with symptoms].
abstract: Progressive systemic sclerosis (PSS) commonly involves the esophagus. Dysphagia and heartburn are the most common esophageal symptoms. In this study we evaluated the relationship between esophageal symptoms and esophago-gastric motility. On esophageal manometry, loss of peristalsis, peristaltic contraction amplitude of distal esophagus less than 30 mmHg and decreased LES pressure were critical for esophageal symptoms. The degree of symptoms correlated to esophageal dysmotility. The gastric emptying in PSS patients was delayed, but there was no significant difference in gastric emptying between the patients with and without reflux esophagitis. Esophageal dysmotility is considered to be much responsible for the reflux esophagitis in PSS patients than gastric emptying.
authors.affiliation: Third Department of Internal Medicine, Tohoku University School of Medicine.
authors.forename: K
authors.initials: K
authors.lastname: Satake
authors.forename: M
authors.initials: M
authors.lastname: Hongo
authors.forename: H
authors.initials: H
authors.lastname: Ujiie
authors.forename: Y
authors.initials: Y
authors.lastname: Okuno
authors.forename: T
authors.initials: T
authors.lastname: Toyota
authors.forename: Y F
authors.initials: YF
authors.lastname: Lin
mesh_terms: D000328:Adult; D015154:Esophageal Motility Disorders / Q000209:etiology / Q000503:physiopathology; D004947:Esophagus / Q000503:physiopathology*; D005260:Female; D005746:Gastric Emptying; D006801:Humans; D008297:Male; D008875:Middle Aged; D010528:Peristalsis; D012595:Scleroderma, Systemic / Q000150:complications / Q000503:physiopathology*