[Immunoscintigraphic follow-up studies with the 99m-Tc marked monoclonal anti-CEA antibody BW 431/26].
Repeated immunoscintigraphy with murine monoclonal antibodies was performed in only few patients because of developing HAMA (Human Anti Mouse Antibodies) and therefore high risk of allergic reactions. Patients with HAMA, which could be observed in about 26% after immunoscintigraphy, show high liver-spleen uptake of labeled monoclonal antibodies in further examinations in some cases.
Fritzsche
H
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Nuklearmedizinischen Abteilung des Landeskrankenhauses Feldkirch.
D000328:Adult; D000368:Aged; D000910:Antibodies, Heterophile / Q000032:analysis*; D000911:Antibodies, Monoclonal / Q000276:immunology; D000936:Antigen-Antibody Complex / Q000032:analysis; D002272:Carcinoembryonic Antigen / Q000276:immunology*; D002277:Carcinoma / Q000000981:diagnostic imaging*; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging*; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging*; D015899:Tomography, Emission-Computed, Single-Photon
D000910:Antibodies, Heterophile; D000911:Antibodies, Monoclonal; D000936:Antigen-Antibody Complex; D002272:Carcinoembryonic Antigen
Immunszintigraphische Kontrolluntersuchungen mit dem 99m-Tc-markierten monoklonalen Anti-CEA-Antikörper BW 431/26.