Effects of heparin versus saline solution on intermittent infusion device irrigation.
The purpose of this study was to compare the effectiveness of 1 ml of 0.9% sodium chloride with 10 units of heparin in 1 ml sodium chloride solution, both containing benzyl alcohol, in maintaining patency and reducing the incidence of phlebitis in patients with intermittent infusion devices. The subjects (N = 32) were randomly assigned in a double-blind experimental design. Repeated-measures analysis of variance revealed no significant difference between the groups in phlebitis or patency variables. The results from this controlled study would suggest that 0.9% sodium chloride is as effective as 10 units of heparin in sodium chloride solution in maintaining intermittent infusion device patency and preventing phlebitis.
Ashton
J
J
Shawnee Mission Medical Center, Mission, KS 66201.
Gibson
V
V
Summers
S
S
D000328:Adult; D000368:Aged; D019905:Benzyl Alcohol; D001592:Benzyl Alcohols / Q000008:administration & dosage / Q000627:therapeutic use; D002408:Catheters, Indwelling; D004311:Double-Blind Method; D004868:Equipment Failure; D005260:Female; D006493:Heparin / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009730:Nursing Assessment; D009737:Nursing Records; D012965:Sodium Chloride / Q000008:administration & dosage* / Q000627:therapeutic use; D007507:Therapeutic Irrigation; D013924:Thrombophlebitis / Q000453:epidemiology / Q000451:nursing / Q000517:prevention & control*
D001592:Benzyl Alcohols; D012965:Sodium Chloride; D006493:Heparin; D019905:Benzyl Alcohol