[The effect of preparations of non-histone chromosomal proteins on the expression of hetero-organic membrane antigens of kidney origin in a primary rat hepatocyte culture].
The expression of membrane hetero-organic antigens of kidney origin, associated with the rat hepatomas in primary culture of intact adult rat hepatocytes, was investigated by means of the indirect immunofluorescence method using a specific immune serum. These antigens were observed on the membrane of some hepatocytes after their contact with nonhistone chromosomal proteins (NHCP), which were obtained from the kidney of intact rats from cells of hepatoma 27 and Zajdela hepatoma, or from the carcinogenic liver after a single diethylnitrosamine injection. Negative results were obtained after the incubation of hepatocytes in the medium lacking some of NHCP, or in that with NHCP obtained from the liver of intact rats.
Ivanov
V A
VA
Fedorov
L Iu
LIu
Grandilevskaia
A B
AB
Klimova
A A
AA
Kushner
V P
VP
Fel'
V Ia
VIa
D000818:Animals; D015478:Antigens, Heterophile / Q000032:analysis / Q000276:immunology*; D000951:Antigens, Neoplasm / Q000032:analysis / Q000276:immunology; D000954:Antigens, Surface / Q000032:analysis / Q000276:immunology; D002462:Cell Membrane / Q000276:immunology; D002478:Cells, Cultured / Q000187:drug effects / Q000276:immunology; D002868:Chromosomal Proteins, Non-Histone / Q000302:isolation & purification / Q000494:pharmacology*; D005455:Fluorescent Antibody Technique; D007668:Kidney / Q000276:immunology*; D008099:Liver / Q000166:cytology / Q000187:drug effects* / Q000276:immunology; D008114:Liver Neoplasms, Experimental / Q000276:immunology / Q000473:pathology; D008297:Male; D051381:Rats; D014407:Tumor Cells, Cultured / Q000187:drug effects / Q000276:immunology
D015478:Antigens, Heterophile; D000951:Antigens, Neoplasm; D000954:Antigens, Surface; D002868:Chromosomal Proteins, Non-Histone
Vliianie preparatov negistonovykh belkov khromatina na ékspressiiu membrannykh geteroorgannykh antigenov pochechnoĭ prirody v pervichnoĭ kul'ture gepatotsitov krys.