[The similarity of the biological effects from the parenteral administration of ascarid antigenic complexes and Salmonella typhi endotoxins].
The experiment with rabbits showed that it was basically possible to develop local and generalized Shwartzman's phenomenon under the combined effect of ascaris antigens and typhoid bacterial endotoxins. Intracutaneous (0.2 ml.) or intravenous (0.1 ml/kg) sensitization of animals by ascaris antigens or microbe endotoxins after repeated intravenous crossover, intravenous injection of the antigens used to result in the development of classical local and generalized Shwartzman's phenomenon.
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D000818:Animals; D000947:Antigens, Helminth / Q000008:administration & dosage / Q000633:toxicity*; D001200:Ascaris / Q000276:immunology*; D001794:Blood Pressure / Q000187:drug effects; D004731:Endotoxins / Q000008:administration & dosage / Q000633:toxicity*; D007275:Injections, Intravenous; D011817:Rabbits; D012485:Salmonella typhi; D012790:Shwartzman Phenomenon / Q000209:etiology / Q000503:physiopathology; D013997:Time Factors
D000947:Antigens, Helminth; D004731:Endotoxins
Skhodstvo biologicheskikh éffektov pri parenteral'nom vvedenii antigennykh kompleksov askarid i éndotoksinov briushnotifoznykh bakteriĭ.