title: Prevalence of human T cell leukemia virus-I (HTLV-I) antibody among populations living in the Amazon region of Brazil (preliminary report).
abstract: Forty-three (31.4%) out of 137 serum samples obtained from two Indian communities living in the Amazon region were found to be positive for HTLV-I antibody, as tested by enzyme-linked immunosorbent assay (ELISA). Eighty-two sera were collected from Mekranoiti Indians, yielding 39% of positivity, whereas 11 (20.0%) of the 55 Tiriyo serum samples had antibody to HTLV-I. In addition, positive results occurred in 10 (23.2%) out of 43 sera obtained from patients living in the Belem area, who were suffering from cancer affecting different organs. Five (16.7%) out of 30 ELISA positive specimens were also shown to be positive by either Western blot analysis (WB) or indirect immunogold electron microscopy (IIG-EM).
authors.affiliation: Instituto Evandro Chagas, Fundação Serviços de Saúde Pública, Belém, PA, Brasil.
authors.forename: C M
authors.initials: CM
authors.lastname: Nakauchi
authors.forename: A C
authors.initials: AC
authors.lastname: Linhares
authors.forename: K
authors.initials: K
authors.lastname: Maruyama
authors.forename: L I
authors.initials: LI
authors.lastname: Kanzaki
authors.forename: J E
authors.initials: JE
authors.lastname: Macedo
authors.forename: V N
authors.initials: VN
authors.lastname: Azevedo
authors.forename: J S
authors.initials: JS
authors.lastname: Casseb
mesh_terms: D000293:Adolescent; D000328:Adult; D015153:Blotting, Western; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D015481:HTLV-I Antibodies / Q000032:analysis*; D015490:HTLV-I Infections / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology*; D015368:Human T-lymphotropic virus 1 / Q000276:immunology*; D006801:Humans; D007150:Immunohistochemistry; D007199:Indians, South American; D007223:Infant; D007231:Infant, Newborn; D008875:Middle Aged; D009369:Neoplasms / Q000097:blood; D015995:Prevalence
chemical_list: D015481:HTLV-I Antibodies