title: [Detection of morphine and codeine in blood samples with gas chromatography/mass spectrometry (NCI and PCI) for differentiating codeine use from use of heroin and morphine].
abstract: Morphine and codeine were isolated from blood with C18 Bond Elut columns and derivatised with pentafluoropropionic anhydride (PFPA). The PFPA-derivatives were examined by means of gas chromatography/mass spectrometry using electron impact and chemical ionisation (positive and negative mode). The negative chemical ionisation, as most sensitive, was applied for the quantitation of both examined substances in forensic blood samples.
authors.affiliation: Institut für Rechtsmedizin, Universität Heidelberg, Bundesrepublik Deutschland.
authors.forename: G
authors.initials: G
authors.lastname: Schmitt
authors.forename: M
authors.initials: M
authors.lastname: Bogusz
authors.forename: R
authors.initials: R
authors.lastname: Aderjan
authors.forename: C
authors.initials: C
authors.lastname: Meyer
mesh_terms: D003061:Codeine / Q000493:pharmacokinetics*; D003937:Diagnosis, Differential; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D003932:Heroin / Q000493:pharmacokinetics*; D006556:Heroin Dependence / Q000097:blood / Q000175:diagnosis*; D006801:Humans; D009020:Morphine / Q000493:pharmacokinetics*; D009021:Morphine Dependence / Q000097:blood / Q000175:diagnosis*
chemical_list: D003932:Heroin; D009020:Morphine; D003061:Codeine
vernacular_title: Zum Nachweis von Morphin und Codein in Blutproben mit GC/MS (NCI und PCI) und zur Unterscheidung einer Codeinaufnahme von Heroin- oder Morphinkonsum.