Leukocyte depletion filters: a comparison of efficiency.
Four commercially available leukocyte depletion filters were evaluated using a flow cytometric technique to determine the efficiency of each type of filter. The Sepacell R-500A and the PALL RC50 were the most efficient in leukocyte depletion having a mean depletion percentage of 99.3% and 99.5%, respectively. The PALL RC100 which is used for two units also had a 99.3% depletion with the first unit but with the second unit the depletion dropped to 94.2%. The imugard IG-500 had a 97.3% depletion. Red cell recovery ranged from 87.4% for the PALL RC50 to 92.2% for the Sepacell R-500A.
Bodensteiner
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Division of Hematology, University of Kansas Medical Center, Kansas City 66103.
D001803:Blood Transfusion; D002469:Cell Separation / Q000379:methods; D004906:Erythrocyte Count; D004912:Erythrocytes / Q000166:cytology*; D005374:Filtration / Q000379:methods; D006801:Humans; D007958:Leukocyte Count; D007962:Leukocytes / Q000166:cytology*