[The antiedematous activity of a table salt substitute, veroshpiron and furosemide in experimental circulatory failure].
On the model of circulatory insufficiency and secondary aldosteronism in rats it was shown that a new table salt substitute normalizes like spironolactone the extracellular fluid volume whereas furosemide exerts a less marked dehydrating action. The antiedema effect of the substitute of table salt is due to a decrease in drinking activity, an increase in natriuresis, normalization of aldosteronism.
Shtrygol'
S Iu
SIu
D000818:Animals; D004195:Disease Models, Animal; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D004487:Edema / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D005665:Furosemide / Q000627:therapeutic use*; D006333:Heart Failure / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D008903:Minerals / Q000627:therapeutic use*; D009318:Natriuresis / Q000187:drug effects; D051381:Rats; D013148:Spironolactone / Q000627:therapeutic use*; D014882:Water-Electrolyte Balance / Q000187:drug effects
D004338:Drug Combinations; D008903:Minerals; D013148:Spironolactone; D005665:Furosemide
Protivootechnaia aktivnost' zamenitelia povarennoĭ soli, veroshpirona i furosemida pri éksperimental'noĭ nedostatochnosti krovoobrashcheniia.