[The reliability of the grading assessment of the biopsy samples in malignant colorectal neoplasms].
The authors evaluate the results of preoperative bioptic grading compared with those obtained from postoperative specimens. Altogether, there was nonagreement in 45% of cases; therefore there is the risk of underestimating the biological aggressiveness of the disease. In fact, 68% of patients who were assessed as G1 in preoperative staging were found to have a higher degree of neoplastic dedifferentiation.
Testa
T
T
Cattedra di Patologia Speciale Chirurgica e Propedeutica Clinica, Università degli Studi di Genova.
Davini
M D
MD
Ottonello
M
M
Capponi
G
G
Scarpettini
S
S
Beatini
M
M
Larghero
G C
GC
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D003106:Colon / Q000473:pathology*; D015179:Colorectal Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D012007:Rectum / Q000473:pathology*; D015203:Reproducibility of Results
Attendibilità della valutazione del grading sui prelievi bioptici per le neoplasie maligne colo-rettali.