[Various characteristics of protein-synthesizing apparatus of the myocardium during total ischemia].
A decrease in the rate of protein synthesis as well as an increase in the synthesis time of "medium-size" polypeptide chain were detected in total rabbit myocardium ischemia, which were evaluated using rabbit myocardium cell-free protein-synthesizing systems. The decrease in the synthesis rate of total myocardial proteins was shown to depend on the state of ribosomes function. Redistribution in the pools of membrane-bound and free ribosomes as well as a decrease of polyribosomes amount in total pool of myocardial ribosomes were observed under conditions of total myocardial ischemia.
Maskoliunas
R K
RK
Lekis
A V
AV
Kovalenko
M I
MI
El'skaia
A V
AV
Lukoshiavichius
L Iu
LIu
D000818:Animals; D002474:Cell-Free System; D003327:Coronary Disease / Q000378:metabolism*; D003600:Cytosol / Q000378:metabolism; D007700:Kinetics; D008297:Male; D009206:Myocardium / Q000378:metabolism*; D014176:Protein Biosynthesis; D012333:RNA, Messenger / Q000378:metabolism; D011817:Rabbits; D012270:Ribosomes / Q000378:metabolism
D012333:RNA, Messenger
Nekotorye osobennosti beloksinteziruiushchego apparata miokarda pri total'noĭ ishemii.