[Simultaneous determination of the GRF and the ERPF (effective renal plasma flow) using a single blood sample in the slope clearance with 99mTc-DTPA and I 131-hippurate].
In patients with various indications to renal split function diagnostics the plasma slope clearance of the Tc99m-DTPA and J131-Hippurate to the estimation of GFR and ERPF were performed with two or three blood samples in the monocompartment model (1 KM). In comparison these functional parameters were calculated on the basis of the only least blood sample (single-point procedure--EPV). The results of linear regression GFR (1 KM) = 12.7 + 0.978 * GFR (EPV), r = 0.986, N = 102 or ERPF (1 KM) = 22 + 1.13 * ERPF (EPV), r = 0.889, N = 68 may recommend the use as patient-safe procedure especially in poor venous access. Two short BASIC programs for estimation of GFR and ERPF are presented and the error ranges discussed.
Schumann
L
L
Klinik für Innere, Wilhelm-Pieck-Universität Rostock.
Esther
G
G
Wüstenberg
P W
PW
Hortian
B
B
D000328:Adult; D005919:Glomerular Filtration Rate; D006626:Hippurates; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D007457:Iodine Radioisotopes; D011866:Radioisotope Renography; D012079:Renal Circulation; D016284:Technetium Tc 99m Pentetate
D006626:Hippurates; D007457:Iodine Radioisotopes; D016284:Technetium Tc 99m Pentetate
Simultane Bestimmung der GFR und des ERPF durch nur eine Blutprobe bei der Slope-Clearance mit 99mTc-DTPA und 131J-Hippurat.