[Molecular-biochemical mechanisms of the effects of nootropic agents].
It is a known fact that prophylactic hypodermic injection of non-typical lithonite tranquillizer in the day's dose of 30 mg/kg during 10 days prevents the exhaustion of antioxidant system of the body, normalizes qualitative and quantitative correlation of separate fractions of phospholipids, stabilizes the permeability of erythrocytic membranes and prevents the development of hypercholesterolemia of the stress. It is concluded that the lithonite's stress-protecting effect is the result of its membrane stabilizing influence.
Kresiun
V I
VI
Rozhkovskiĭ
Ia V
IaV
D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D000975:Antioxidants / Q000378:metabolism; D001921:Brain / Q000187:drug effects; D002462:Cell Membrane / Q000187:drug effects / Q000201:enzymology; D004912:Erythrocytes / Q000187:drug effects; D008297:Male; D010889:Piracetam / Q000494:pharmacology*; D051381:Rats; D011919:Rats, Inbred Strains; D013312:Stress, Physiological / Q000201:enzymology / Q000517:prevention & control; D013997:Time Factors; D014149:Tranquilizing Agents / Q000494:pharmacology*; D005680:gamma-Aminobutyric Acid / Q000031:analogs & derivatives* / Q000494:pharmacology
D000700:Analgesics; D000975:Antioxidants; D014149:Tranquilizing Agents; C044905:nicotinoyl-GABA; D005680:gamma-Aminobutyric Acid; D010889:Piracetam
Molekuliarno-biokhimicheskie mekhanizmy deĭstviia nootropnykh sredstv.