title: Potent inhibitors of de novo pyrimidine and purine biosynthesis as chemotherapeutic agents.
authors.affiliation: Department of Biochemistry, University of Sydney, NSW, Australia.
authors.forename: R I
authors.initials: RI
authors.lastname: Christopherson
authors.forename: S D
authors.initials: SD
authors.lastname: Lyons
mesh_terms: D000818:Animals; D004791:Enzyme Inhibitors / Q000737:chemistry; D005472:Fluorouracil / Q000737:chemistry; D005493:Folic Acid Antagonists / Q000494:pharmacology; D005973:Glutamine / Q000037:antagonists & inhibitors; D009374:Neoplasms, Experimental / Q000188:drug therapy; D011687:Purines / Q000037:antagonists & inhibitors*; D011743:Pyrimidines / Q000037:antagonists & inhibitors*
chemical_list: D004791:Enzyme Inhibitors; D005493:Folic Acid Antagonists; D011687:Purines; D011743:Pyrimidines; D005973:Glutamine; D005472:Fluorouracil