In vitro susceptibility of Xanthomonas (Pseudomonas) maltophilia to newer antimicrobial agents.
The susceptibilities of 45 clinical and 3 environmental isolates of Xanthomonas maltophilia to 14 antimicrobial agents was determined by broth microdilution. The newer quinolones PD117596, PD117558, PD127391, A-56620, amifloxacin, and fleroxacin were the most active agents tested, with 70 to 99% of isolates being susceptible to these agents. All isolates were resistant to trospectomycin. The new aminoglycosides SCH24120 and SCH22591 were active against 12 and 1% of isolates, respectively.
Khardori
N
N
Department of Medical Specialties, University of Texas M. D. Anderson Cancer Center, Houston 77030.
Reuben
A
A
Rosenbaum
B
B
Rolston
K
K
Bodey
G P
GP
D042462:4-Quinolones; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003470:Culture Media; D006801:Humans; D008826:Microbial Sensitivity Tests; D011549:Pseudomonas / Q000187:drug effects*; D011552:Pseudomonas Infections / Q000382:microbiology
D042462:4-Quinolones; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D003470:Culture Media