[The cytogenetic effect of natural mutagenesis modifiers in a human lymphocyte culture. The action of aminobenzamide during the gibberellic acid induction of chromosome aberrations].
The 3-aminobenzamide sensibilization of the cytogenetic activity of gibberellic acid in the culture of human lymphocytes has been investigated. Two-three-fold increase of the chromosome aberrations induced by gibberellic acid, irrespective of the time of 3-aminobenzamide addition to the cultures (the 28th, 46th, 72th hrs of the cultivation) is shown.
Zalinian
G G
GG
Arutiunian
R M
RM
Sarkisian
G G
GG
D000328:Adult; D001549:Benzamides / Q000494:pharmacology*; D002478:Cells, Cultured / Q000187:drug effects; D002869:Chromosome Aberrations / Q000235:genetics*; D004247:DNA / Q000037:antagonists & inhibitors*; D004260:DNA Repair / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D005875:Gibberellins / Q000494:pharmacology*; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects*; D016296:Mutagenesis / Q000187:drug effects* / Q000235:genetics; D010937:Plant Growth Regulators / Q000494:pharmacology*; D013997:Time Factors
D001549:Benzamides; D005875:Gibberellins; D010937:Plant Growth Regulators; C025160:3-aminobenzamide; D004247:DNA; C007842:gibberellic acid
Tsitogeneticheskiĭ éffekt estestvennykh modifikatorov mutageneza v kul'ture limfotsitov cheloveka. Deĭstvie aminobenzamida pri induktsii aberratsiĭ khromosom gibberellovoĭ kislotoĭ.