title: [Validity of the direct immunofluorescent monoclonal antibody test in the diagnosis of chlamydial infection].
abstract: The sensitivity and specificity of direct fluorescent monoclonal antibody staining were compared with the isolation of the organisms in McCoy cells. For both diagnostic methods cervical smears were taken in 120 women. Of 120 women 25 (20.8%) were infertile, 60 (50.0%) healthy fertile women and 35 (29.8%) adolescents who came for control gynecological examination. C. trachomatis was isolated in 5/25 (20.0%) of infertile women, in 5/60 (8.3%) of healthy fertile women and in 4/35 (11.4%) adolescents. With the cell culture as the reference method, the antigen detection test had a sensitivity of 92.8%, a specificity of 98.1%, a positive predictive value of 86.7% and a negative predictive value of 99.1%.
authors.affiliation: Centar za ginekolosku endokrinologiju i fertilitet Klinike za zenske bolesti i porode Medicinskog fakulteta Sveucilista u Zagrebu.
authors.forename: H
authors.initials: H
authors.lastname: Vrcić
authors.forename: V
authors.initials: V
authors.lastname: Simunić
authors.forename: V
authors.initials: V
authors.lastname: Grizelj
authors.forename: E
authors.initials: E
authors.lastname: Suchanek
authors.forename: V
authors.initials: V
authors.lastname: Kruzicević
mesh_terms: D000293:Adolescent; D000328:Adult; D000911:Antibodies, Monoclonal; D002690:Chlamydia Infections / Q000175:diagnosis*; D002692:Chlamydia trachomatis / Q000276:immunology; D005260:Female; D005455:Fluorescent Antibody Technique; D005831:Genital Diseases, Female / Q000175:diagnosis*; D006801:Humans
chemical_list: D000911:Antibodies, Monoclonal
vernacular_title: Valjanost direktne imunofluorescencije monoklonskim protutijelima u dijagnostici klamidijske infekcije.