[The content of a heparin-like anticoagulant in the flowers of the meadowsweet (Filipendula ulmaria)].
The flowers of Filipendula ulmaria were found to contain heparin bound to the plant proteins in the form of a complex. This complex enhances the anticoagulant and fibrinolytic properties of the nonenzymatic nature at its administration to animals both intramuscularly and intravenously. The neutralizing effect of protaminesulphate on the anticoagulant activity of the plant heparin was shown. The identity of the action on the hemostasis system of heparin of animal and plant origin was found.
Kudriashov
B A
BA
Liapina
L A
LA
Azieva
L D
LD
D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects; D005342:Fibrinolysis / Q000187:drug effects; D006493:Heparin / Q000032:analysis* / Q000302:isolation & purification / Q000494:pharmacology; D008297:Male; D010940:Plant Proteins / Q000032:analysis; D010946:Plants, Medicinal / Q000032:analysis*; D011479:Protamines / Q000494:pharmacology; D011485:Protein Binding; D051381:Rats; D013997:Time Factors
D010940:Plant Proteins; D011479:Protamines; D006493:Heparin
Soderzhanie geparinopodobnogo antikoagulianta v tsvetkakh tavolgi viazolistnoĭ.