Calmitine: a calcium-binding mitochondrial protein specific for fast-twitch muscle fibers.
Mitochondrial fractions were isolated from fast-twitch (EDL), slow-twitch (soleus) and heart muscle of normal rat (WKY). Protein separation by electrophoresis and study of calcium-45 binding showed that a specific calcium protein (designated as calmitine) was present in the mitochondria of fast-twitch muscle but practically inexistent in slow-twitch and cardiac muscle. It seems to be related to calcium uptake by an energy-dependent mechanism.
Lucas-Heron
B
B
Laboratoire de Physiologie--U.E.R. de Médecine, Nantes, France.
Schmitt
N
N
Ollivier
B
B
D000375:Aging; D000818:Animals; D002118:Calcium / Q000378:metabolism; D002135:Calcium-Binding Proteins / Q000302:isolation & purification* / Q000378:metabolism; D004591:Electrophoresis, Polyacrylamide Gel; D006321:Heart / Q000254:growth & development*; D008929:Mitochondria, Heart / Q000378:metabolism*; D008931:Mitochondria, Muscle / Q000378:metabolism*; D024510:Muscle Development; D009928:Organ Specificity; D051381:Rats; D011921:Rats, Inbred WKY
D002135:Calcium-Binding Proteins; D002118:Calcium