Ultra structure study of schistosomula recovered after cercarial penetration of isolated skin.
The ultrastructure, development and antigenic nature of the surface and the viability of schistosomula formed after cercariae had penetrated isolated skin has been studied. Within 2 hours of transformation, the surface membrane of schistosomula had changed from trilaminate to heptalaminate structures and lost their cercarial glycocalyx. The preacetabular glands of schistosomula were emptied, the mixed agglutination reaction demonstrated the presence of human A and B blood group-like antigenic determinant on approximately 30% of 3 hours old schistosomula. The first schistosomula reached the gut closed stage by day 12 (50-70%), and between 40% of all schistosomula developed to maturity when injected intravenously into mice.
Abou-Zakham
A A
AA
Department of Parasitology, Faculty of Medicine, Mansoura University, Egypt.
Romia
S A
SA
el-Naggar
H S
HS
el-Khouly
E S
ES
D000372:Agglutination Tests; D000818:Animals; D000947:Antigens, Helminth / Q000096:biosynthesis; D046508:Culture Techniques; D051379:Mice; D008854:Microscopy, Electron; D012550:Schistosoma mansoni / Q000276:immunology / Q000648:ultrastructure*; D012867:Skin / Q000469:parasitology*
D000947:Antigens, Helminth