Assignment of the human nicotinic acetylcholine receptor genes: the alpha and delta subunit genes to chromosome 2 and the beta subunit gene to chromosome 17.
The chromosomal assignments of the genes coding for the alpha, beta and delta subunits of the human nicotinic acetylcholine receptor have been determined from a panel of somatic cell hybrids and by direct in situ hybridization. The results localize CHRNA to 2q24-2q32. CHRNB to 17p11-17p12, and CHRND to chromosome 2q33-2qter.
Beeson
D
D
Institute for Molecular Medicine, John Radcliffe Hospital, Oxford.
Jeremiah
S
S
West
L F
LF
Povey
S
S
Newsom-Davis
J
J
D000818:Animals; D015139:Blotting, Southern; D002874:Chromosome Mapping; D002886:Chromosomes, Human, Pair 17; D002889:Chromosomes, Human, Pair 2; D015342:DNA Probes; D006801:Humans; D006822:Hybrid Cells; D011978:Receptors, Nicotinic / Q000235:genetics*
D015342:DNA Probes; D011978:Receptors, Nicotinic