title: [Campylobacter pylori and treatment of duodenal ulcer].
abstract: The authors subjected to endoscopic examination 90 patients with duodenal ulcers. From each patient they collected a bioptic specimen of the gastric antrum and duodenal bulbus for microbiological and histological examination. They found that for detection of C. pylori the microscopic examination was most useful. The presence of C. pylori in the gastric antrum was detected in 87% of the subjects and in the duodenal bulb only in 48%. The difference is significant at the 0.01 level. To 43 patients of the group Ranitidine was administered. The ulcer was cured within 4 weeks in 35 subjects. Ranitidine did not affect the presence of C. pylori and antral gastritis. After cure of the ulcer the authors administered Tarivid to 10 patients with persisting C. pylori positivity. The presence of C. pylori and antral gastritis were not affected by this treatment.
authors.affiliation: I. Interní klinika fakulty dĕtského lékarství Univerzity Karlovy, Praha.
authors.forename: J
authors.initials: J
authors.lastname: Zelenková
authors.forename: R
authors.initials: R
authors.lastname: Toman
authors.forename: M
authors.initials: M
authors.lastname: Bielaszewská
authors.forename: J
authors.initials: J
authors.lastname: Hanika
authors.forename: V
authors.initials: V
authors.lastname: Zeman
mesh_terms: D000328:Adult; D002167:Campylobacter / Q000302:isolation & purification; D002169:Campylobacter Infections / Q000188:drug therapy*; D004381:Duodenal Ulcer / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D005756:Gastritis / Q000188:drug therapy / Q000382:microbiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015242:Ofloxacin / Q000627:therapeutic use; D011899:Ranitidine / Q000627:therapeutic use
chemical_list: D011899:Ranitidine; D015242:Ofloxacin
vernacular_title: Campylobacter pylori a lécba duodenálního vredu.