[Behavior of ionized calcium in hypertensive and normotensive patients].
Serum concentrations of ionized calcium have been measured in a group of 38 patients with essential hypertension (26 women and 12 men with mean age 61 +/- 12 years) and in a group of 19 normotensives (14 women and 5 men with mean age 70 +/- 12 years). Serum Ca++ levels were significantly lower in hypertensives than in normotensives (4.16 +/- 0.43 mg/dl and 4.46 +/- 0.38 mg/dl respectively, with p less than 0.05). The lower serum concentrations found in hypertensives may be due ions in arterial smooth muscle cells may cause an increase of vascular tone and peripheral resistances. Our results support, in agreement with other Authors, the possible role of ionized calcium in the pathogenesis of essential hypertension.
Ricciardelli
D
D
Istituto di Clinica Medica Generale e Terapia Medica III, U.S.L. 10/D, Firenze.
Piccini
L
L
Forgeschi
M
M
Sanna
A
A
Bandinelli
R
R
Pala
A M
AM
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002118:Calcium / Q000097:blood*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000209:etiology; D008297:Male; D008875:Middle Aged
D002118:Calcium
Comportamento del calcio ionizzato in soggetti ipertesi e normotesi.