title: Evaluation of an automated bleeding time device in the newborn.
abstract: Sick infants frequently developed impaired hemostasis as a secondary event. Abnormal platelet-vessel wall interaction contributes to the hemorrhagic side effects. Currently, the bleeding time is the best measure of in vivo platelet participation in small vessel hemostasis. Bleeding times in the newborn have been previously determined with an automated device designed for the adult or with nonautomated devices. The automated bleeding time device for the adult is not suitable for the infant (length 5 mm, depth 1 mm). We evaluated the performance of an automated bleeding time device designed specifically for the newborn making a cut 2.5 mm in length and 0.5 mm in depth. The results with the automated device showed a strong correlation with the modified template bleeding time device previously used for the newborn. The normal range was shorter and the sensitivity to abnormal vessel wall interaction was greater with the automated device. As well, the ease of determining the bleeding time with the automated device was considerably improved over the template device.
authors.affiliation: Department of Pediatrics, St. Joseph's Hospital, Hamilton, Ontario, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Andrew
authors.forename: B
authors.initials: B
authors.lastname: Paes
authors.forename: J
authors.initials: J
authors.lastname: Bowker
authors.forename: P
authors.initials: P
authors.lastname: Vegh
mesh_terms: D001760:Bleeding Time; D004864:Equipment and Supplies / Q000592:standards; D005069:Evaluation Studies as Topic; D006801:Humans; D007223:Infant