title: Sacroepidural analgesia for post-operative pain relief in children.
abstract: For evaluation of the practicality of epidural analgesia for alleviation of post-operative pain, 66 class I or II patients with age ranging from 6 months to 12 years undergoing elective surgical procedures below the lower abdomen were enrolled for study during the period from January to April 1989. Before termination of general anesthesia a single dose of 0.25% bupivacaine, respectively at 0.25 mL/kg (Ideal body weight), 0.5 mL/kg, 0.75 mL/kg, 1.0 mL/kg and 1.25 mL/kg was given sacroepidurally to 5 groups of patients. Our results showed that for surgery below the lower abdomen a dose at 1.0 mL/kg was sufficient to suffice the need for relief of post-operative pain. At this dosage it achieved a neural block up to T8-T6 and provided with an analgesia that could last 6.0 +/- 2.1 hours. During the entire course there were no untoward effects such as hypotension, bradycardia, vomiting and shivering to come about. Therefore, sacroepidural analgesia with 0.25% bupivacaine at fitting single dose is safe and feasible in children as far as relief of post-operative pain for procedures below the lower abdomen is concerned.
authors.affiliation: Department of Anesthesiology, Venterans General Hospital-Taipei, National Yang-Ming Medical College.
authors.forename: L H
authors.initials: LH
authors.lastname: Haung
authors.forename: S S
authors.initials: SS
authors.lastname: Hseu
authors.forename: K
authors.initials: K
authors.lastname: Liu
authors.forename: S K
authors.initials: SK
authors.lastname: Tsai
authors.forename: K F
authors.initials: KF
authors.lastname: Tseng
authors.forename: G M
authors.initials: GM
authors.lastname: Huang
authors.forename: T Y
authors.initials: TY
authors.lastname: Lee
mesh_terms: D015360:Analgesia, Epidural / Q000379:methods*; D001835:Body Weight; D002045:Bupivacaine / Q000008:administration & dosage; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D010149:Postoperative Pain / Q000628:therapy*; D012044:Regression Analysis
chemical_list: D002045:Bupivacaine