title: [Clinical studies on 9 patients with Heberden's nodes of premenopausal onset].
abstract: Nine patients with Heberden's nodes of premenopausal onset were studied for complications in the form of thyroid disorders as well as from the hereditary, roentgenological and immunological aspects. In addition, rheumatoid arthritis, psoriatic arthritis, traumatic arthritis, erosive osteoarthritis or adult Still's disease was excluded in these patients. All patients had thyroid disorder (Basedow's disease in 6 patients, Hashimoto's thyroiditis in 2 patients and granular thyroiditis in one patient). Immunological examinations were positive for anti-thyroglobulin antibody in 5 patients and anti-microsome antibody in 3 patients and anti-nuclear antibody in 2 patients. Roentgenological findings revealed no typical signs of primary generalized osteoarthritis.
authors.affiliation: Department of Joint Disease, Nippon Medical School, Tokyo.
authors.forename: S
authors.initials: S
authors.lastname: Yoshino
authors.forename: J
authors.initials: J
authors.lastname: Fujimori
authors.forename: A
authors.initials: A
authors.lastname: Kajino
authors.forename: I
authors.initials: I
authors.lastname: Hara
mesh_terms: D000328:Adult; D000367:Age Factors; D000974:Antibodies, Antinuclear / Q000032:analysis; D005260:Female; D005384:Finger Joint; D006801:Humans; D007159:Immunologic Tests; D008593:Menopause; D008875:Middle Aged; D012218:Rheumatoid Nodule / Q000150:complications / Q000175:diagnosis*; D013959:Thyroid Diseases / Q000150:complications
chemical_list: D000974:Antibodies, Antinuclear