title: [Thrombolysis therapy and coronary angiography in acute myocardial infarct in the Augsburg region: results of the Augsburger Heart infarct register 1985-1987].
abstract: In the years 1985-87, the Augsburg Coronary Event Register registered 1333 hospitalized patients who had survived an acute myocardial infarction (AMI) for at least 24 h. In 953 patients, data on time intervals in the prehospital phase were documented in addition to the medical records data in a standardized nurse interview. The time from onset of AMI until the patient called for medical attention constituted most of the prehospital time delay. Of the interviewed male and female patients, 67% were hospitalized within 6 h (= time limit). The differences, both in the number of thrombolyses and the number of coronary angiographies performed in men and in women are statistically significant. Thrombolysis was performed in 27% of the male and 12% of the female AMI patients who were admitted to hospital within the time limit. The rate of thrombolytic therapy decreased with increasing age and was less in patients with recurrent AMI (men: 20%, women: 0%) than in patients with first AMI (men: 29%, women: 15%). There was some time-of-day variation in the percentage of thrombolytic therapy which may be attributable to hospital organization. From 1985 to 1987, the coronary angiography rates performed in the medical center doubled, independent of the thrombolytic therapy rates. In this time, angiography rates in thrombolyzed patients increased from 49% to 75%, and from 14% to 31% in patients without thrombolysis. The 28-day case fatality was 4.8% in patients with thrombolysis and 13% in patients without thrombolytic therapy. Controlling for age, sex, and recurrent AMI, this difference is not statistically significant.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: GSF, München, Medis-Institut, Neuherberg.
authors.forename: H
authors.initials: H
authors.lastname: Löwel
authors.forename: A
authors.initials: A
authors.lastname: Hörmann
authors.forename: M
authors.initials: M
authors.lastname: Lewis
authors.forename: W
authors.initials: W
authors.lastname: Krawietz
authors.forename: H D
authors.initials: HD
authors.lastname: Bolte
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000790:Angiocardiography; D004632:Emergency Medical Services; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D011379:Prognosis; D015912:Thrombolytic Therapy; D013997:Time Factors
vernacular_title: Thrombolysetherapie und Koronarangiographie bei akutem Myokardinfarkt in der Region Augsburg: Ergebnisse des Augsburger Herzinfarktregisters 1985-1987.