title: [2 fluorophotometric methods of measuring aqueous humor flow in hypertensive patients].
abstract: Two fluorophotometric methods, by instillation and oral route, allowed the aqueous humor flow measurement and apparent outflow resistance calculation in normal and hypertensive subjects. There was no statistically significant difference between the two methods in the aqueous humor flow of hypertensive patients and normal subjects. On the contrary, there was an increase of the outflow resistance in hypertensive patients in relation to normal subjects. Finally, oral route fluorophotometry allowed the individualization and calculation of a coefficient of aqueous humor production from the iris, which is statistically increased in hypertensive in comparison with normal subjects. Subsequent studies thanks to this fluorophotometric method by oral route, which interest is certain in treated hypertensive patients, should allow to determine the action site of the drug and to quantify its efficiency.
authors.affiliation: Clinique Ophtalmologique, CHRU, Hôpital Saint-Jacques, Clermont-Ferrand.
authors.forename: J M
authors.initials: JM
authors.lastname: Ménérath
authors.forename: L M
authors.initials: LM
authors.lastname: Coulangeon
authors.forename: M
authors.initials: M
authors.lastname: Sole
authors.forename: P
authors.initials: P
authors.lastname: Sole
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber; D001082:Aqueous Humor / Q000378:metabolism / Q000502:physiology*; D003315:Cornea; D005452:Fluoresceins / Q000008:administration & dosage; D015590:Fluorophotometry / Q000379:methods*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D007908:Lens, Crystalline; D008875:Middle Aged; D009798:Ocular Hypertension / Q000503:physiopathology*; D009883:Ophthalmic Solutions
chemical_list: D005452:Fluoresceins; D009883:Ophthalmic Solutions
vernacular_title: Deux méthodes fluorophotométriques de mesure de débit d'humeur aqueuse chez le sujet hypertone.