Hereditary polymorphisms of human drug metabolizing enzymes and cancer susceptibility.
Gonzalez
F J
FJ
Laboratory of Molecular Carcinogenesis, National Institutes of Health, Bethesda, MD 20892.
D000818:Animals; D001711:Biotransformation / Q000502:physiology; D002273:Carcinogens / Q000493:pharmacokinetics*; D003577:Cytochrome P-450 Enzyme System / Q000737:chemistry / Q000235:genetics* / Q000502:physiology; D003647:Debrisoquin / Q000493:pharmacokinetics; D020022:Genetic Predisposition to Disease; D006801:Humans; D008617:Mephenytoin / Q000493:pharmacokinetics; D009369:Neoplasms / Q000139:chemically induced*; D010084:Oxidation-Reduction; D011110:Polymorphism, Genetic / Q000235:genetics*
D002273:Carcinogens; D003577:Cytochrome P-450 Enzyme System; D008617:Mephenytoin; D003647:Debrisoquin