[Application of convolution curve method for simultaneous determination of four components in somidon].
The computer-aided convolution curve method has been applied to the determination of phenacetin, aminopyrine, caffeine and phenobarbitone in the tablet of somidon without prior separation. The convolution curve method is a compound difference method developed on the basis of Glenn's orthogonal function using computer information treatment technique. The corresponding average recovery and the coefficients of variation were as follows: 99.96, 0.36% for phenacetin; 99.76, 0.43% for aminopyrine; 99.98, 0.48% for caffeine and 99.26, 0.89% for phenobarbitone.
Wu
Y T
YT
Second Military Medical University, Shanghai.
Wang
G F
GF
Gong
H L
HL
D000632:Aminopyrine / Q000032:analysis; D000700:Analgesics / Q000032:analysis*; D002110:Caffeine / Q000032:analysis; D004338:Drug Combinations; D008722:Methods; D010615:Phenacetin / Q000032:analysis; D010634:Phenobarbital / Q000032:analysis; D013607:Tablets
D000700:Analgesics; D004338:Drug Combinations; D013607:Tablets; D000632:Aminopyrine; D002110:Caffeine; D010615:Phenacetin; D010634:Phenobarbital