[The protective action of the organic substances in naftusia water on erosive-ulcerative lesions of the gastric mucosa in rats undergoing immobilization-cold stress].
It is shown that 7-11-day long consumption (by rats) of water naftusia or organic matters isolated from it which contain carbonic acids and catecholamines possessing paramagnetic activity exerts a preventive effect on stress injuries of the mucous membrane of the stomach. Gastric protective action of naftusia goes with hyperplasia and hypertrophy of argyrophil endocrinocytes and antral mucosa, with an increase of gastrin content in it as well as in blood serum, shortening of the nembutal sleep duration.
Popovich
I L
IL
Ivasivka
S V
SV
Iasevich
A P
AP
Gavdiak
M V
MV
Bilyk
I I
II
D000818:Animals; D003080:Cold Temperature / Q000009:adverse effects*; D004353:Drug Evaluation, Preclinical; D005753:Gastric Mucosa / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D005755:Gastrins / Q000378:metabolism; D008900:Mineral Waters / Q000032:analysis; D051381:Rats; D011919:Rats, Inbred Strains; D012149:Restraint, Physical / Q000009:adverse effects; D013276:Stomach Ulcer / Q000209:etiology / Q000378:metabolism / Q000473:pathology / Q000517:prevention & control*; D013312:Stress, Physiological / Q000150:complications* / Q000378:metabolism / Q000473:pathology; D013997:Time Factors
D005755:Gastrins; D008900:Mineral Waters
Zashchitnoe deĭstvie organicheskikh veshchestv vody naftusi na érozivno-iazvennye povrezhdeniia slizistoĭ obolochki zheludka u krys pri immobilizatsionno-kholodovom stresse.