title: Excitability changes in the crustacean motor axons following activity.
abstract: It has been shown experimentally that the crustacean motor axon is supernormally excitable following a train of action potentials (Zucker 1974). Such a phenomenon can lead to recruitment of terminals which are unexcited at low rates of stimulation. Although currents underlying the crustacean motor axon have been characterized (Connor et al. 1977), it is not known whether this membrane model accounts for a supernormal period, what might cause superexcitability in this model, or how excitability might change during repetitive stimulation. In present study, it is demonstrated that the crustacean motor axon model does predict a supernormal period, that the supernormal period results from slow recovery from inactivation of the transient potassium, or A, current, and that supernormal excitability is enhanced by repetitive stimulation.
authors.affiliation: Department of Surgery, University of Alberta, Edmonton, Canada.
authors.forename: N
authors.initials: N
authors.lastname: Stockbridge
authors.forename: N
authors.initials: N
authors.lastname: Yamoah
mesh_terms: D000200:Action Potentials; D000818:Animals; D001369:Axons / Q000502:physiology*; D002462:Cell Membrane / Q000502:physiology; D003445:Crustacea; D008433:Mathematics; D008959:Models, Neurological; D009046:Motor Neurons / Q000502:physiology*