title: [The provocation test in children with cow-milk protein and gluten intolerance: evaluation of the clinical response and lesions in the mucous membrane of the small intestine].
abstract: Provocation test (re-introduction of the noxious protein) was carried out in two groups of patients: (a) with intolerance to the cow-milk proteins (41 children) treated with milk-free diet for 6-24 months, and (b) with gluten intolerance (26 children) treated with gluten-free diet for 6-36 months. The following parameters were compared: type and frequency of the clinical symptoms seen in these patients prior to the introduction of allergen-free diet. Moreover, the type of observed morphological changes in the small intestine mucosa following provocation test were analysed in the groups of 7 patients. A two-year elimination of milk from the diet produces milk tolerance in about 61% patients; clinical symptoms in the remaining children are diversified. Re-introduction of gluten with the diet (provocation test) produces recurrence of gluten intolerance in 96% of children treated with gluten-free diet for 2-3 years. Recurrence of the disease was accompanied by the atrophy of the intestinal villi.
authors.affiliation: Kliniki Chorób Zakaźnych Dzieci AM w Białymstoku.
authors.forename: M
authors.initials: M
authors.lastname: Kaczmarski
mesh_terms: D001284:Atrophy; D002675:Child, Preschool; D004044:Dietary Proteins / Q000009:adverse effects*; D005983:Glutens / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D007413:Intestinal Mucosa / Q000473:pathology*; D007421:Intestine, Small / Q000473:pathology*; D016269:Milk Hypersensitivity / Q000178:diet therapy / Q000473:pathology*; D012008:Recurrence
chemical_list: D004044:Dietary Proteins; D005983:Glutens
vernacular_title: Próba prowokacyjna u dzieci z nietolerancja białek mleka krowiego i glutenu: ocena reakcji klinicznych i zmian w błonie śluzowej jelita cienkiego.