title: Central venous stasis retinopathy following the use of tranexamic acid.
abstract: Central venous stasis retinopathy (CVSR) was observed in two young women following the administration of oral tranexamic acid (TA) for the treatment of menorrhagia. Clinical and laboratory parameters were normal. Withdrawal of the drug and treatment with systemic steroids and fibrinolytic drugs resulted in improvement of visual acuity to 6/6. The pathogenesis of the CVSR in these cases is suggested, and the rationale of systemic treatment is discussed.
authors.affiliation: Department of Ophthalmology, Beilinson Medical Center, Petah Tikva, Israel.
authors.forename: M
authors.initials: M
authors.lastname: Snir
authors.forename: R
authors.initials: R
authors.lastname: Axer-Siegel
authors.forename: G
authors.initials: G
authors.lastname: Buckman
authors.forename: Y
authors.initials: Y
authors.lastname: Yassur
mesh_terms: D000328:Adult; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D007958:Leukocyte Count; D008595:Menorrhagia / Q000188:drug therapy; D012170:Retinal Vein Occlusion / Q000139:chemically induced*; D014148:Tranexamic Acid / Q000009:adverse effects* / Q000627:therapeutic use; D014792:Visual Acuity
chemical_list: D014148:Tranexamic Acid