title: [Resemblance of magnesium and zinc distribution in soft tissues and bone of rats fed unbalanced mineral diets in situ].
abstract: Although the role of zinc (Zn) and magnesium (Mg) in situ may be of a critical importance in replication, transcription and repair of DNA, to our knowledge, the relationship between Mg and Zn has been described. This study, therefore, was designed experimentally to investigate the relationship between Mg and Zn in soft tissues and bone of rats after fortification of unbalanced mineral diets, and minerals and metals in soft tissues and bone were determined by inductively coupled plasma emission spectrometry. In the groups fed low calcium (Ca) diet, low Ca-Mg diet and low Ca-Mg plus high Al diet, serum Mg level was lower in the group fed low Ca-Mg diet and low Ca-Mg plus high Al diet than those in the groups fed standard diet and low Ca diet. However, there was no significant difference in Mg content of CNS tissues in rats fed unbalanced and standard diets except for that in the spinal cord of rats fed low Ca-Mg plus high Al diet. Whereas, Zn content of CNS showed lower values in the unbalanced mineral diet groups, especially in all CNS regions of the low Ca-Mg plus high Al diet group, than those in the standard and the low Ca diet group. And Zn contents in heart, kidney and abdominal aorta of rats fed low Ca-Mg diet and low Ca-Mg plus high Al diet were more decreased than those of the standard and the low Ca diet groups.(ABSTRACT TRUNCATED AT 250 WORDS)
authors.affiliation: Division of Neurological Diseases, Wakayama Medical College, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Yasui
authors.forename: Y
authors.initials: Y
authors.lastname: Yase
authors.forename: E
authors.initials: E
authors.lastname: Shimizu
authors.forename: K
authors.initials: K
authors.lastname: Ota
mesh_terms: D000535:Aluminum / Q000008:administration & dosage; D000818:Animals; D001842:Bone and Bones / Q000378:metabolism*; D002118:Calcium / Q000008:administration & dosage; D002490:Central Nervous System / Q000378:metabolism*; D005526:Food, Formulated; D008274:Magnesium / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D008297:Male; D008903:Minerals / Q000008:administration & dosage*; D051381:Rats; D011919:Rats, Inbred Strains; D014018:Tissue Distribution; D014781:Viscera / Q000378:metabolism; D015032:Zinc / Q000097:blood / Q000493:pharmacokinetics*
chemical_list: D008903:Minerals; D000535:Aluminum; D008274:Magnesium; D015032:Zinc; D002118:Calcium