title: A computerised technique for the quantitative assessment of resorption cavities in trabecular bone.
abstract: A computerised technique is described for the quantitative assessment of resorption cavities in iliac trabecular bone. Using an Ibas II image analyser, the original bone surface, eroded by bone resorbing cells, is reconstructed using a curve fitting technique that maintains a smooth continuity with the trabecular bone on either side of the cavity. Resorption depths are measured using an interactive elastic circle; all identified cavities are measured regardless of whether or not resorption is complete, and the measurements made include mean and maximum cavity depth, cavity length, area, and adjacent trabecular widths. Results in 13 normal subjects are presented. The technique is reproducible, simple to operate, relatively rapid, and can be applied to less sophisticated image analysis systems.
authors.affiliation: Dept. of Pathology, University of Wales College of Medicine, Heath Park, Cardiff, UK.
authors.forename: N J
authors.initials: NJ
authors.lastname: Garrahan
authors.forename: P I
authors.initials: PI
authors.lastname: Croucher
authors.forename: J E
authors.initials: JE
authors.lastname: Compston
mesh_terms: D000328:Adult; D000368:Aged; D001862:Bone Resorption / Q000473:pathology*; D003627:Data Interpretation, Statistical; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D015203:Reproducibility of Results