Pheochromocytoma presenting as rhabdomyolysis and acute myoglobinuric renal failure.
We report the case of a previously healthy young woman who presented with the sudden onset of rhabdomyolysis and myoglobinuric renal failure, requiring hemodialysis for 3 weeks. Common causes of rhabdomyolysis were ruled out; as renal function returned, severe hypertension was noted and a pheochromocytoma was diagnosed. We suggest that pheochromocytoma causes rhabdomyolysis and myoglobinuria via catecholamine-mediated vasoconstriction and skeletal muscle ischemia.
Shemin
D
D
Department of Medicine, Rhode Island Hospital, Providence 02903.
Cohn
P S
PS
Zipin
S B
SB
D058186:Acute Kidney Injury / Q000209:etiology*; D000310:Adrenal Gland Neoplasms / Q000150:complications*; D000328:Adult; D005260:Female; D006801:Humans; D006977:Hypertension, Renal / Q000209:etiology; D009212:Myoglobinuria / Q000209:etiology; D010673:Pheochromocytoma / Q000150:complications*; D012206:Rhabdomyolysis / Q000209:etiology*