title: Montpellier Cancer Institute strategy and experience in surgical treatment of multi-bilateral hepatic metastases from digestive tract cancers.
abstract: Montpellier Cancer Institute strategy and experience in surgical treatment of multi-bilateral hepatic metastases from digestive tract cancers is presented based on retrospective case by case analysis of survival time of 38 patients. The mean age was 46.2 years and the primaries were colorectal (22 patients) and endocrine (16 patients). Liver surgery was synchronous to the resection of primary lesions in 8 patients and metachronous in 22 patients. Two-step liver surgery was performed in 8 patients. Overall thirty-days postoperative mortality was 7.8% and morbidity 15.7% (wound sepsis, subphrenic abscess, transitory jaundice, biliary fistula). The analysis of survival time evidenced that with reasonable risk-benefit ratio the aggressive surgical approach can be justified especially in patients with endocrine primaries.
authors.affiliation: Department of Surgery and Nutrition, University of Montpellier, France.
authors.forename: H
authors.initials: H
authors.lastname: Joyeux
authors.forename: B
authors.initials: B
authors.lastname: Saint-Aubert
authors.forename: A W
authors.initials: AW
authors.lastname: Szawłowski
authors.forename: C
authors.initials: C
authors.lastname: Solassol
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000328:Adult; D000368:Aged; D015179:Colorectal Neoplasms / Q000473:pathology*; D005602:France; D015408:Gastrinoma / Q000473:pathology*; D005935:Glucagonoma / Q000473:pathology*; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000473:pathology*; D013964:Thyroid Neoplasms / Q000473:pathology