[Usefulness of ventilation and perfusion scans in patients with collagen-vascular diseases].
We studied 32 patients with collagen-vascular diseases with Xe-133 ventilation scans (V) and Tc-99m MAA perfusion scans (Q). Five patients underwent sequential studies at intervals of more than 3 months. Mean transit time (MTT) was calculated from the Xe-133 wash-out curve. V, Q images and MTT were compared with chest X-ray films and the values of %DLco. Of 32 patients, 17 had no abnormal finding on the chest X-ray films. Of the 17 patients, however, V and/or Q abnormalities were found in 10 (59%), 14 patients (82%), respectively. Every patient with abnormal findings on the chest X-ray film showed both V and Q abnormalities. Overall, Q abnormality was more frequent and severer than V one. Of the 5 patients with the sequential studies, 3 showed prolongation of MTT in concordance with deterioration of pulmonary fibrosis. V and Q abnormalities were not necessarily relevant to %DLco. In conclusion, ventilation and perfusion studies are useful in assessing the regional pulmonary function in patients with collagen-vascular diseases.
Kosuda
S
S
Department of Radiology, Tokyo Metropolitan Komagome Hospital.
Shioyama
Y
Y
Kamata
N
N
Akita
S
S
Mezaki
T
T
Kawakami
R
R
Suzuki
K
K
D000328:Adult; D003095:Collagen Diseases / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013668:Technetium Tc 99m Aggregated Albumin; D014692:Ventilation-Perfusion Ratio; D014980:Xenon Radioisotopes
D013668:Technetium Tc 99m Aggregated Albumin; D014980:Xenon Radioisotopes