[Cyclosporin A-induced gingival hyperplasias: cross-sectional study of young organ transplantation patients].
In this study 137 patients (30 adolescence, 2-21 years, 107 adults, 22-68 years), which had been treated with Cyclosporine-A, between 17 to 2461 days after organ transplantation, were examinated by gingival status. The severity of gingival hyperplasia increases in both groups with mean transplantations period, independent of mean daily doses of CsA and Azathioprin and independent of mean plasma concentration. Adolescence and adults differ significantly, in relation of each severity group frequency. The adolescence group includes 66.7% of the cases with gingival enlargement of severity degree 3. In both groups increases the mean value of PGI-Index with the severity degree.
Günay
H
H
Zentrum Zahn-, Mund- und Kieferheilkunde, Medizinische Hochschule Hannover.
Beier
C
C
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D003524:Cyclosporins / Q000009:adverse effects*; D005260:Female; D005885:Gingival Hyperplasia / Q000139:chemically induced*; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D016377:Organ Transplantation
D003524:Cyclosporins
Cyclosporin-A-induzierte Gingivahyperplasien: Eine Querschnittsuntersuchung jugendlicher, organtransplantierter Patienten.