[Transplantation of immature allogeneic testis].
Experimental and clinical studies (109 rat and 17 dog experiments and four clinical transplantations of a neonatal testis to children with the postcastration syndrome and postnatal hypoplasia of their own testes) showed that transplantation of an immature testis makes it possible to reduce to maximum its damage on exposure to the effect of unspecific and specific factors of transplantation. The transplantation ensures prolonged viability and function of the allogeneic male sexual gland, which is confirmed by the maintenance of its specific structures (the ultrastructural level among others) in the late-term postoperative period, the ability of immature allogeneic transplants to restore the sexual behaviour of castrated animal recipients, and by the positive results of clinical test of the method.
Kirpatovskiĭ
I D
ID
Gorbatiuk
D L
DL
D000818:Animals; D000831:Animals, Newborn / Q000601:surgery*; D004285:Dogs; D006085:Graft Survival / Q000502:physiology; D006801:Humans; D007006:Hypogonadism / Q000503:physiopathology / Q000601:surgery*; D007231:Infant, Newborn; D008297:Male; D009919:Orchiectomy / Q000379:methods; D051381:Rats; D013737:Testis / Q000002:abnormalities / Q000503:physiopathology / Q000637:transplantation*; D014184:Transplantation, Homologous
Transplantatsiia nepolovozrelogo allogennogo iaichka.