title: Pigmented villonodular synovitis and plasmacytoid lymphoma in a dog.
abstract: A 4-year-old Labrador Retriever was examined because of progressive left hind limb lameness involving the stifle. A villous synovial mass was evacuated by synovectomy. Initially, the macroscopic and histopathologic features suggested a malignant fibrosarcomatous process; however, further histologic studies revealed lesions consistent with pigmented villonodular synovitis. Nine months later, the dog developed a large retroperitoneal tumor, with metastasis to the lungs and liver. The dog was then euthanatized. By histologic and electron microscopic examinations, the tumor was found to be a primitive plasmacytoid lymphoma.
authors.affiliation: Third Department of Medicine, Helsinki University Central Hospital, Finland.
authors.forename: T
authors.initials: T
authors.lastname: Somer
authors.forename: K
authors.initials: K
authors.lastname: Sittnikow
authors.forename: K
authors.initials: K
authors.lastname: Henriksson
authors.forename: E
authors.initials: E
authors.lastname: Saksela
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005260:Female; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D012186:Retroperitoneal Neoplasms / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D013586:Synovitis, Pigmented Villonodular / Q000150:complications / Q000473:pathology / Q000662:veterinary*