title: Plasmodium falciparum-infected Anopheles stephensi inconsistently transmit malaria to humans.
abstract: Malaria was transmitted to only 5 of 10 volunteers bitten by 1-2 Anopheles stephensi carrying sporozoites of the 3D7 clone of the NF54 strain of Plasmodium falciparum in their salivary glands. Parasites were detectable by culture in blood taken 7-10 days following exposure and by thick blood film 14-16.5 days after exposure. Infectivity did not correlate with the numbers of sporozoites in the salivary glands.
authors.affiliation: National Naval Medical Center, Bethesda, Maryland.
authors.forename: L S
authors.initials: LS
authors.lastname: Rickman
authors.forename: T R
authors.initials: TR
authors.lastname: Jones
authors.forename: G W
authors.initials: GW
authors.lastname: Long
authors.forename: S
authors.initials: S
authors.lastname: Paparello
authors.forename: I
authors.initials: I
authors.lastname: Schneider
authors.forename: C F
authors.initials: CF
authors.lastname: Paul
authors.forename: R L
authors.initials: RL
authors.lastname: Beaudoin
authors.forename: S L
authors.initials: SL
authors.lastname: Hoffman
mesh_terms: D000328:Adult; D000818:Animals; D000852:Anopheles / Q000469:parasitology*; D001733:Bites and Stings; D006801:Humans; D007303:Insect Vectors / Q000469:parasitology; D008288:Malaria / Q000635:transmission*; D008297:Male; D010963:Plasmodium falciparum / Q000502:physiology*