Successful aztreonam treatment of acute typhoid fever after chloramphenicol failure.
Aztreonam treatment was successful in 4 cases of typhoid fever. The patients were seriously ill with growth of Salmonella typhi in blood cultures despite treatment with chloramphenicol. Aztreonam appears to be a useful alternative to standard therapy of typhoid fever.
Farid
Z
Z
US Naval Medical Research Unit No.3, FPO, New York, NY 09527-1600.
Girgis
N I
NI
Kamal
M
M
Bishay
E
E
Kilpatrick
M E
ME
D000328:Adult; D001398:Aztreonam / Q000627:therapeutic use*; D002701:Chloramphenicol / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D012485:Salmonella typhi / Q000254:growth & development; D014435:Typhoid Fever / Q000097:blood / Q000188:drug therapy*
D002701:Chloramphenicol; D001398:Aztreonam