[Poisoning of retinal pigment epithelium by deferoxamine. A case report].
A patient undergoing hemodialysis was treated intravenously with desferrioxamine (3 g) for an aluminum encephalopathy. He presented a sudden xanthopsia with visual loss. Fundus examination showed diffuse macular irregular pigmentary disturbances. We discuss current knowledge and possible pathogenesis of these observations published since 1983. Awareness of the side effects of desferrioxamine implies an ophthalmologic follow up similar as chloroquine.
Charton
N
N
Clinique Ophtalmologique, Hôpital Civil, Strasbourg.
Sahel
J A
JA
Flament
J
J
D000368:Aged; D003676:Deferoxamine / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010857:Pigment Epithelium of Eye / Q000187:drug effects*; D006435:Renal Dialysis; D012164:Retinal Diseases / Q000139:chemically induced / Q000209:etiology
D003676:Deferoxamine
Intoxication de l'épithélium pigmentaire rétinien par la déféroxamine--a propos d'une observation.