title: [Management of gas gangrene in Hungary during 1979-1988 based on data from Public Health Centers].
abstract: Authors present data on the therapy of 223 gas gangrene cases between 1979-1988, a ten years period, based on the reports of Public Health Stations in Hungary. Of the 223 patients 150 died, thus lethality was 67.3%. In lack of surgical intervention there was no chance of survive. Merely wound exposure resulted in a much higher fatality rate than necrectomy of the wound. Local hydrogen-hyperoxide treatment improved survival essentially. Specific antitoxin therapy did not influence the survival rate. The effect of a single antibiotic was poor; combined antibiotic treatment gave a significantly better result. As for combination, the most effective were erythromycin, the lincosamids and chloramphenicol. According to the data presented, it would be possible to reduce to the half the fatality rate of gas gangrene in Hungary.
authors.affiliation: Országos Johan Béla Közegészségügyi Intézet, Budapest.
authors.forename: G
authors.initials: G
authors.lastname: Sere
authors.forename: G
authors.initials: G
authors.lastname: Petrás
authors.forename: G
authors.initials: G
authors.lastname: Páll
authors.forename: A
authors.initials: A
authors.lastname: Szönyi
mesh_terms: D000900:Anti-Bacterial Agents; D003646:Debridement; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005738:Gas Gangrene / Q000453:epidemiology* / Q000401:mortality / Q000628:therapy; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D006861:Hydrogen Peroxide / Q000008:administration & dosage; D009336:Necrosis / Q000601:surgery; D015996:Survival Rate
chemical_list: D000900:Anti-Bacterial Agents; D006861:Hydrogen Peroxide
vernacular_title: A gázgangréna kezelése Magyarországon 1979-1988-ban a KOJAL-ok adatai alapján.