title: [The epidemiological aspect of chronic kidney lesions of drug origin].
abstract: In order to establish the prevalence of the intake of the most widely used nephrotropic drugs (non-steroidal anti-inflammatory agents and analgesic-antipyretic drugs), the authors have carried out epidemiological studies among the urban population. 5996 persons living in Riga were examined according to the designed by the authors 4-staged system using computer at the final stage. All the examined underwent analysis of the morning portion of urine. The drugs indicated were discovered to be taken for a long time in 14% of cases (in 15.4 among women and in 11.8% among men). The use of the drugs was motivated by degenerative dystrophic alterations in the bones and joints (56.27%), complicated virus infections (9.68%), headache (2.99%), and by combination of the three enumerated causes (30.34%). In 0.72% of cases, the causes of drug intake could not be established. Depending on the presence of a concrete urinary symptom, a high relative and a high absolute risk of the development of chronic tubulointerstitial renal lesions provoked by drugs have been defined in cases of the prolonged use of the drugs under study.
authors.forename: Ia P
authors.initials: IaP
authors.lastname: Zal'kans
authors.forename: N N
authors.initials: NN
authors.lastname: Zhuravleva
mesh_terms: D000367:Age Factors; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D002908:Chronic Disease; D006801:Humans; D007049:Iatrogenic Disease / Q000453:epidemiology; D007674:Kidney Diseases / Q000139:chemically induced / Q000453:epidemiology*; D007844:Latvia / Q000453:epidemiology; D012307:Risk Factors; D014505:Urban Population / Q000706:statistics & numerical data
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal
vernacular_title: Epidemiologicheskiĭ aspekt khronicheskikh porazheniĭ pochek lekarstvennogo proiskhozhdeniia.