title: Serum fructosamine concentrations in Singapore pregnant women.
abstract: Serum fructosamine levels in women at pregnancy (28 weeks' gestation) were determined. The women (n = 99) also participated in an oral glucose tolerance test (OGTT) with a 75g liquid glucose load, to determine their glucose tolerance. At 32 weeks' gestation, seventy-nine of them repeated the oral glucose tolerance test and fructosamine measurement. Results showed that fructosamine levels in pregnant women with normal glucose tolerance (2.20 +/- 0.19 mmol/l, n = 76), were not statistically different from those with glucose intolerance (gestational diabetes: 2.19 +/- 0.22 mmol/l, n = 23) at 28 weeks' and also 32 weeks' gestation. However, serum fructosamine levels in pregnant women were lower than those in non-pregnant subjects. Serum fructosamine measurement is not a sufficiently sensitive test for diagnosis of gestational diabetes.
authors.affiliation: Department of Medicine, National University Hospital, Singapore.
authors.forename: A C
authors.initials: AC
authors.lastname: Thai
authors.forename: L P
authors.initials: LP
authors.lastname: Kek
authors.forename: W Y
authors.initials: WY
authors.lastname: Ng
authors.forename: O A
authors.initials: OA
authors.lastname: Viegas
authors.forename: M
authors.initials: M
authors.lastname: Rauff
mesh_terms: D000328:Adult; D005260:Female; D019270:Fructosamine; D005951:Glucose Tolerance Test / Q000295:instrumentation; D006595:Hexosamines / Q000097:blood*; D006801:Humans; D011247:Pregnancy / Q000097:blood*; D011254:Pregnancy in Diabetics / Q000097:blood*; D011897:Random Allocation; D012016:Reference Values; D012846:Singapore; D013997:Time Factors
chemical_list: D006595:Hexosamines; D019270:Fructosamine