Immunoradiometric assay for prolactin in serum and tissue--comparison with radioimmunoassay.
Prolactin (PRL) concentrations in sera and tumors of patients with various pituitary tumors were measured by both immunoradiometric assay (IRMA) and radioimmunoassay (RIA). PRL concentrations in sera and tumor tissues measured by IRMA were well correlated with those measured by RIA. PRL concentrations in sera reflected those of tumors removed. This IRMA is a simple and useful method for PRL determination in serum and tissue.
Ohnami
S
S
Department of Radiology, University of Occupational and Environmental Health Hospital, Kitakyushu-shi, Japan.
Nakata
H
H
Eto
S
S
D000172:Acromegaly / Q000097:blood / Q000378:metabolism; D000236:Adenoma / Q000097:blood / Q000378:metabolism; D003480:Cushing Syndrome / Q000097:blood / Q000378:metabolism; D006801:Humans; D015592:Immunoradiometric Assay; D010900:Pituitary Diseases / Q000097:blood / Q000378:metabolism*; D010911:Pituitary Neoplasms / Q000097:blood / Q000378:metabolism; D011388:Prolactin / Q000032:analysis* / Q000097:blood; D015175:Prolactinoma / Q000097:blood / Q000378:metabolism; D011863:Radioimmunoassay; D012680:Sensitivity and Specificity
D011388:Prolactin