[Role of bone marrow glycosaminoglycans in the reaction of the hematopoietic tissue to extreme conditions].
The authors studied medullary glucosaminoglycans of rats and mice in extreme effects (hypoxia, hyperbaric oxygenation, inflammation, radiation, cooling, hemorrhage). Four types of reaction were determined which cause different changes of proliferation of hematopoietic cells. Hematopoiesis stimulation is accompanied by regular change of types of reaction of hematopoietic microenvironment. Its disturbance affects the changes of hematopoiesis and blood regeneration rate. It was shown that the increase of neutral glucosaminoglycans concentrations in bone marrow depended on the play ground and proliferative activity of erythroid sprout and that of acid glucosaminoglycans--primarily of granulocytic sprout.
Tsvirenko
S V
SV
Sharavara
A A
AA
Iushkov
V G
VG
Iastrebov
A P
AP
D000818:Animals; D001853:Bone Marrow / Q000737:chemistry / Q000502:physiology*; D006025:Glycosaminoglycans / Q000032:analysis* / Q000502:physiology*; D006410:Hematopoiesis; D006470:Hemorrhage / Q000503:physiopathology; D006931:Hyperbaric Oxygenation; D007035:Hypothermia / Q000503:physiopathology; D000860:Hypoxia / Q000503:physiopathology; D007249:Inflammation / Q000503:physiopathology; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D011829:Radiation Dosage; D011830:Radiation Effects; D051381:Rats; D011919:Rats, Inbred Strains
D006025:Glycosaminoglycans
O roli glikozaminoglikanov kostnogo mozga v reaktsii krovetvornoĭ tkani pri ékstremal'nykh vozdeĭstviiakh.