Ro 40-7592, a novel, very potent, and orally active inhibitor of catechol-O-methyltransferase: a pharmacological study in rats.
Zürcher
G
G
Pharmaceutical Research Department, F. Hoffmann-La Roche Ltd, Basle, Switzerland.
Keller
H H
HH
Kettler
R
R
Borgulya
J
J
Bonetti
E P
EP
Eigenmann
R
R
Da Prada
M
M
D000284:Administration, Oral; D000818:Animals; D001577:Benzophenones / Q000494:pharmacology*; D065098:Catechol O-Methyltransferase Inhibitors; D046508:Culture Techniques; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D009596:Nitrophenols; D051381:Rats; D013329:Structure-Activity Relationship; D000077867:Tolcapone
D001577:Benzophenones; D065098:Catechol O-Methyltransferase Inhibitors; D009596:Nitrophenols; D000077867:Tolcapone