Breast nodules as the initial site of relapse in childhood leukemia.
Two children with acute monoblastic leukemia in remission developed breast nodules that were the initial sites of disease relapse. Shortly after the appearance of disease in this site, the children developed marrow recurrence and, despite additional treatment, rapidly deteriorated and died from pancytopenia-related complications. The importance of careful breast examination is stressed as part of the surveillance physical examination for children with monoblastic leukemia.
Weinblatt
M E
ME
Department of Pediatrics, North Shore University Hospital-Cornell University Medical College, Manhasset, New York 11030.
Kochen
J
J
D000293:Adolescent; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D007948:Leukemia, Monocytic, Acute / Q000188:drug therapy / Q000473:pathology*; D009364:Neoplasm Recurrence, Local; D012074:Remission Induction