title: Auditory steady-state responses in the rabbit.
abstract: The authors have studied auditory brainstem (ABRs), middle latency (MLRs) and steady-state potentials (SSRs) in 15 adult male rabbits weighing between 2.5 and 3 kg in order to verify if SSRs are due to a mere superimposition of ABRs and MLRs or to a resonance phenomenon. Ten of them were awake while 5 were studied under urethane anesthesia. Acoustic stimuli consisted in 0.1-ms square-wave pulses delivered at presentation rates ranging between 1 and 80/s at a stimulus intensity of 80 dB p.e. SPL. Our data show that reliable auditory SSRs can be obtained in the rabbit at a presentation rate of 30 stimuli/s, probably due to the superimposition of ABRs and MLR Pb waves which show an interwave interval of about 35 ms. The nonlinear aspects which can be detected are probably due to the effect of decreasing interstimulus intervals on the duration and amplitude of the Pb wave. It can then be concluded that SSRs in the rabbit are due more to a superimposition of ABR and MLR waves than to a resonance phenomenon.
authors.affiliation: Institute of Otorhinolaryngology, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Ottaviani
authors.forename: G
authors.initials: G
authors.lastname: Paludetti
authors.forename: S
authors.initials: S
authors.lastname: Grassi
authors.forename: F
authors.initials: F
authors.lastname: Draicchio
authors.forename: R M
authors.initials: RM
authors.lastname: Santarelli
authors.forename: G
authors.initials: G
authors.lastname: Serafini
authors.forename: V E
authors.initials: VE
authors.lastname: Pettorossi
mesh_terms: D000161:Acoustic Stimulation; D000768:Anesthesia, General; D000818:Animals; D001143:Arousal / Q000502:physiology; D005072:Evoked Potentials, Auditory / Q000187:drug effects / Q000502:physiology*; D016057:Evoked Potentials, Auditory, Brain Stem / Q000187:drug effects / Q000502:physiology*; D008297:Male; D011817:Rabbits; D011930:Reaction Time / Q000187:drug effects / Q000502:physiology*; D014520:Urethane / Q000494:pharmacology
chemical_list: D014520:Urethane