title: [Pharmacologic effects and safety profile of bethanechol in the differential diagnosis of pseudo-anginal thoracic pain].
abstract: The use of bethanecol has recently been proposed to improve the diagnostic accuracy of esophageal manometry in identifying the origin of symptoms in patients with non cardiac chest pain. In this study we report our experience in 30 patients who underwent esophageal functional studies. Despite its low diagnostic value, bethanecol test (two subsequential doses of 50 micrograms/kg) demonstrated an excellent safety profile, there were few side effects, and patients tolerance was good. The Holter electrocardiographic study showed an isolated case of transient atrioventricular block.
authors.affiliation: Divisione Medica, Clinica Chirurgica I, Università di Padova.
authors.forename: G
authors.initials: G
authors.lastname: Mastrapasqua
authors.forename: L
authors.initials: L
authors.lastname: Bonavina
authors.forename: M
authors.initials: M
authors.lastname: Anselmino
authors.forename: D
authors.initials: D
authors.lastname: Madia
authors.forename: L
authors.initials: L
authors.lastname: De Vido
authors.forename: M
authors.initials: M
authors.lastname: Baessato
authors.forename: G
authors.initials: G
authors.lastname: Suzzi
mesh_terms: D000368:Aged; D000787:Angina Pectoris / Q000175:diagnosis*; D001626:Bethanechol Compounds / Q000009:adverse effects; D002637:Chest Pain / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012449:Safety
chemical_list: D001626:Bethanechol Compounds
vernacular_title: Effetti farmacologici e profilo di sicurezza del betanecolo cloruro nella diagnosi differenziale del dolore toracico pseudo-anginoso.