Renal dysfunction associated with ciprofloxacin.
We cared for a 64-year-old woman who experienced increased serum creatinine levels after 8 days of ciprofloxacin therapy. She had previously received a course of several antibiotics, including gentamicin. Renal function returned to normal 18 days after the ciprofloxacin was discontinued. This is the eighth reported case of nephrotoxicity associated with this agent. The mechanism and predisposing factors have not been defined.
Hatton
J
J
Department of Pharmacy, University of Kentucky College of Pharmacy, Lexington 40536-0084.
Haagensen
D
D
D058186:Acute Kidney Injury / Q000097:blood / Q000139:chemically induced* / Q000382:microbiology; D002939:Ciprofloxacin / Q000009:adverse effects*; D003404:Creatinine / Q000097:blood*; D005260:Female; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D007671:Kidney Concentrating Ability; D008875:Middle Aged; D013997:Time Factors
D005839:Gentamicins; D002939:Ciprofloxacin; D003404:Creatinine