title: [Mega-dosages vitamin D: progressive medicine?].
abstract: Although the risk of vitamin intoxication is well recognised, massive doses of these preparations continue to be prescribed, especially in the so-called 'alternative' medical sector. We describe a patient with hypervitaminosis D due to administration of megadoses of vitamin D in the absence of an obvious indication. Mode of action and symptoms of vitamin D intoxication are discussed. It is emphasized that vitamin preparations should only be used when strictly indicated and that close clinical and biochemical supervision is necessary.
authors.affiliation: Academisch Ziekenhuis, Afd. Inwendige Geneeskunde, Nijmegen.
authors.forename: P J
authors.initials: PJ
authors.lastname: Kerstens
authors.forename: T J
authors.initials: TJ
authors.lastname: van Ditzhuijsen
authors.forename: J H
authors.initials: JH
authors.lastname: van Tongeren
mesh_terms: D000328:Adult; D000529:Complementary Therapies; D005260:Female; D006261:Headache / Q000628:therapy*; D006801:Humans; D006934:Hypercalcemia / Q000139:chemically induced* / Q000628:therapy; D009974:Orthomolecular Therapy / Q000009:adverse effects*; D014807:Vitamin D / Q000008:administration & dosage / Q000506:poisoning*
chemical_list: D014807:Vitamin D
vernacular_title: Megadoses vitamine D: progressieve geneeskunde?