title: Abnormal hemorheological parameters in vertebrobasilar-insufficiency.
abstract: Thirty-seven patients, aged 47 +/- 22 years, diagnosed suffering from vertebrobasilar insufficiency (VBI), underwent a hemorheological examination; 20% of these patients had no vascular risk-factor but none showed complete normal hemorheological findings. The distribution of hemorheological parameters was comparable to those in patients suffering from stroke or TIA. Abnormal were platelet-reactivity in 78%, plasma-viscosity in 57%, fibrinogen in 23%, red-blood-cell-aggregation in 13% and hematocrit in 11% of all cases. To obtain more information on how to classify common clinical symptoms i.e. headache in combination with vertigo it may be useful to introduce hemorheological parameters as platelet-reactivity, plasma-viscosity, fibrinogen, in the further laboratory examination of those patients.
authors.affiliation: Department of Neurology, University of Münster, West Germany.
authors.forename: K H
authors.initials: KH
authors.lastname: Grotemeyer
mesh_terms: D000328:Adult; D000368:Aged; D001809:Blood Viscosity / Q000502:physiology*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D004903:Erythrocyte Aggregation / Q000502:physiology*; D005260:Female; D005340:Fibrinogen / Q000378:metabolism*; D006400:Hematocrit; D006801:Humans; D002546:Ischemic Attack, Transient / Q000097:blood / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000502:physiology*; D014715:Vertebrobasilar Insufficiency / Q000097:blood / Q000175:diagnosis*
chemical_list: D005340:Fibrinogen