title: Osteomyelitis due to Cryptococcus neoformans in advanced age. Case report and review of literature.
abstract: In an 84-year-old man cryptococcosis with a pronounced osteomyelitic course (involvement of a rib, two thoracic vertebrae, the sacrum and a femur) was diagnosed histologically post mortem, thus directing attention to cryptococcosis in advanced age. The presumptive chronic course of the Cryptococcus neoformans (Cr. n.) infection in this patient was ascribed to chronic kidney failure, diabetes mellitus and chronic obstructive lung disease. Special reference is made to the mycological and radiological diagnosis of cryptococcosis of the bones as well as to its pathogenesis, therapy and epidemiology.
authors.affiliation: Pathological Institute, Rudolf Virchow University Hospital, Wedding, Berlin, Germany FR.
authors.forename: R
authors.initials: R
authors.lastname: Kromminga
authors.forename: F
authors.initials: F
authors.lastname: Staib
authors.forename: U
authors.initials: U
authors.lastname: Thalmann
authors.forename: G
authors.initials: G
authors.lastname: Jautzke
authors.forename: M
authors.initials: M
authors.lastname: Seibold
authors.forename: H
authors.initials: H
authors.lastname: Hochrein
authors.forename: H
authors.initials: H
authors.lastname: Witt
authors.forename: H
authors.initials: H
authors.lastname: Bürger
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003453:Cryptococcosis / Q000382:microbiology* / Q000473:pathology; D003455:Cryptococcus neoformans / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D010019:Osteomyelitis / Q000382:microbiology* / Q000473:pathology