Influence of bovine immunoglobulin G on faradaic reactions at electrodes.
The effect of bovine immunoglobulin G (IgG), adsorbed on different electrode materials, on faradaic reactions of hexacyanoferrate(III)-hexacyanoferrate(II), hydroquinone-benzoquinone, nicotinamide adenine dinucleotide, reduced from (NADH), and phenol is described and discussed. The reactions are partially inhibited by IgG, but the current and peak potentials reach protein-independent values for higher concentrations of IgG. The hydroquinone-benzoquinone couple can be used for detection purposes at IgG-covered electrodes in electrochemical immunoassays.
Emons
H
H
Department of Chemistry, Karl-Marx University of Leipzig, GDR.
Heineman
W R
WR
D015374:Biosensing Techniques; D004566:Electrodes; D007118:Immunoassay / Q000379:methods*; D007074:Immunoglobulin G; D010084:Oxidation-Reduction
D007074:Immunoglobulin G