title: Prolonged remission after cyclosporine therapy in pemphigus vulgaris: report of two young siblings.
abstract: We report the clinical evolution of two young siblings with severe pemphigus vulgaris treated with cyclosporine for 30 and 12 months, respectively. One was resistant to treatment with high-dose corticosteroids and azathioprine. A good clinical response was achieved in both cases. No major side effects were observed. The patients have remained disease free for more than 20 months after stopping cyclosporine therapy.
authors.affiliation: Department of Internal Medicine, Valle de Hebron General Hospital, Autonomous University of Barcelona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Alijotas
authors.forename: R
authors.initials: R
authors.lastname: Pedragosa
authors.forename: J
authors.initials: J
authors.lastname: Bosch
authors.forename: M
authors.initials: M
authors.lastname: Vilardell
mesh_terms: D002648:Child; D003524:Cyclosporins / Q000627:therapeutic use*; D005192:Family Health; D005260:Female; D006801:Humans; D008297:Male; D010392:Pemphigus / Q000188:drug therapy*; D012074:Remission Induction
chemical_list: D003524:Cyclosporins