title: Brain and liver dolichol in chronic alcoholism: a necropsy study.
abstract: Cerebral gray and white matter and liver dolichol levels were measured in postmortem samples from chronic alcoholics and nonalcoholic controls following recent suggestions that dolichol levels may be used as a marker for alcoholism. No significant differences in brain dolichol were found between the control and alcoholic groups. A significant reduction in the liver dolichol was observed in the alcoholic group. This was most marked in those alcoholics with liver disease.
authors.affiliation: Department of Pathology, University of Sydney, Australia.
authors.forename: J J
authors.initials: JJ
authors.lastname: Kril
authors.forename: R K
authors.initials: RK
authors.lastname: Pullarkat
authors.forename: P S
authors.initials: PS
authors.lastname: Pullarkat
authors.forename: C G
authors.initials: CG
authors.lastname: Harper
mesh_terms: D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000473:pathology*; D001921:Brain / Q000473:pathology*; D004286:Dolichols / Q000378:metabolism*; D005235:Fatty Liver, Alcoholic / Q000473:pathology; D005260:Female; D006801:Humans; D008099:Liver / Q000473:pathology*; D008104:Liver Cirrhosis, Alcoholic / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010296:Parietal Lobe / Q000473:pathology
chemical_list: D004286:Dolichols