title: Management of local and regional recurrence after mastectomy or breast-conserving treatment.
abstract: Locoregional failures after primary treatment for breast cancer include a diverse group of lesions that represent different categories of failures with various prognoses. Although patients with chest wall recurrences and regional nodal failures after traditional radical surgery have a poor prognosis, many patients can still achieve a significant degree of palliation and even long-term survival or cure with carefully orchestrated multimodal treatment. In patients who have breast failures after breast-conservation surgery and radiation, long-term salvage and cure can be achieved for the majority with prompt detection and appropriate treatment, which, like treatment for primary breast cancer, includes a consideration not only of local control but also of the risk of subsequent systemic failure and its need for treatment.
authors.affiliation: University of Texas M.D. Anderson Cancer Center, Houston.
authors.forename: F C
authors.initials: FC
authors.lastname: Ames
authors.forename: C M
authors.initials: CM
authors.lastname: Balch
mesh_terms: D001940:Breast / Q000601:surgery*; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008408:Mastectomy; D009364:Neoplasm Recurrence, Local; D015996:Survival Rate