Plasmodium falciparum-infected Anopheles stephensi inconsistently transmit malaria to humans.
Malaria was transmitted to only 5 of 10 volunteers bitten by 1-2 Anopheles stephensi carrying sporozoites of the 3D7 clone of the NF54 strain of Plasmodium falciparum in their salivary glands. Parasites were detectable by culture in blood taken 7-10 days following exposure and by thick blood film 14-16.5 days after exposure. Infectivity did not correlate with the numbers of sporozoites in the salivary glands.
Rickman
L S
LS
National Naval Medical Center, Bethesda, Maryland.
Jones
T R
TR
Long
G W
GW
Paparello
S
S
Schneider
I
I
Paul
C F
CF
Beaudoin
R L
RL
Hoffman
S L
SL
D000328:Adult; D000818:Animals; D000852:Anopheles / Q000469:parasitology*; D001733:Bites and Stings; D006801:Humans; D007303:Insect Vectors / Q000469:parasitology; D008288:Malaria / Q000635:transmission*; D008297:Male; D010963:Plasmodium falciparum / Q000502:physiology*