title: [Local treatment of malignant pleural effusion in gynecologic tumors].
abstract: Pleural effusions are a frequent complication of malignant gynecologic diseases, especially in breast cancer with an incidence of about 50%. Pleural effusions usually occur at a stage of the disease where no further curative therapeutic options exist. Therefore, the treatment should be effective and have a low side effect profile. The intrapleural administration of mitoxantrone in comparison with other pleurodesis techniques has been demonstrated to meet these requirements.
authors.affiliation: Frauenklinik und Hebammenlehranstalt der Georg-August-Universität, Göttingen.
authors.forename: D
authors.initials: D
authors.lastname: Seitzer
authors.forename: E
authors.initials: E
authors.lastname: Musch
authors.forename: W
authors.initials: W
authors.lastname: Kuhn
mesh_terms: D001943:Breast Neoplasms / Q000188:drug therapy*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008942:Mitoxantrone / Q000008:administration & dosage* / Q000009:adverse effects; D010051:Ovarian Neoplasms / Q000188:drug therapy*; D016066:Pleural Effusion, Malignant / Q000188:drug therapy*
chemical_list: D008942:Mitoxantrone
vernacular_title: Die lokale Behandlung maligner Pleuraergüsse bei gynäkologischen Tumoren.