title: The effect of tamoxifen on semen fertilization capacity in White Leghorn male chicks.
abstract: Tamoxifen (TAM) is an antiestrogen that advances sexual puberty in cockerels, turkey toms, and Muscovy drakes. The effect of TAM on semen-fertilization capacity in White Leghorn (WL) male chicks was assayed in the present study. Sixty, 2-wk-old, male chicks were divided into two equal groups. The chicks from one group were injected im with 1 mg of TAM per kg of BW every other day; those from the second group were vehicle-treated (with corn oil) and served as controls. Each chick was paired with a virgin, WL laying hen. When semen was produced, the paired female was inseminated twice a week. The results revealed that TAM administration caused the early production of fertile semen, which resulted in the first normal descendants as early as 8 wk of age and brought about 100% of parenthood by the age of 88 days.
authors.affiliation: Department of Animal Science, Faculty of Agriculture, Hebrew University of Jerusalem, Rehovot, Israel.
authors.forename: B
authors.initials: B
authors.lastname: Robinzon
authors.forename: I
authors.initials: I
authors.lastname: Rozenboim
authors.forename: E
authors.initials: E
authors.lastname: Arnon
authors.forename: N
authors.initials: N
authors.lastname: Snapir
mesh_terms: D000818:Animals; D002645:Chickens / Q000502:physiology*; D005298:Fertility / Q000187:drug effects*; D008297:Male; D012661:Semen / Q000187:drug effects* / Q000502:physiology; D013629:Tamoxifen / Q000494:pharmacology*
chemical_list: D013629:Tamoxifen