Ankylosing spondylitis and other spondyloarthropathies.
Ankylosing spondylitis and related spondyloarthropathies show a remarkable association with a genetic marker--HLA-B27--and also illustrate the relationship between host and environmental factors. HLA-B27 has revitalized the epidemiology of spondyloarthropathies and has helped to broaden the clinical spectrum of these diseases. These and other aspects of descriptive and genetic epidemiology are reviewed.
Khan
M A
MA
Case Western Reserve University, Cleveland, Ohio.
van der Linden
S M
SM
D006801:Humans; D015995:Prevalence; D011379:Prognosis; D013167:Spondylitis, Ankylosing / Q000453:epidemiology / Q000209:etiology / Q000473:pathology*