title: [The pathomorphology and pathogenesis of acute cardiovascular failure in swine. 3. Histopathologic findings in the myocardium of swine with transport-related cardiovascular insufficiency].
abstract: Quantitative pathohistological investigations were performed on 300 samples of five different myocardial regions from 50 pigs with had suffered stress-related myocardial insufficiency on their transport to the slaughterhouse (transport exhaustion). The findings were compared to 1,200 myocardial samples from 200 clinically intact pigs for slaughter. Animals with transport-related damage exhibited with significance more and more severe inflammatory and degenerative myocardial alterations, such as round-cell infiltration, fiber necrosis, calcification, and fat infiltration. Many of these lesions had been manifest already prior to transport. Myocardially predamaged pigs were less capable than others of sustaining transport stress and were more predisposed to cardiac failure. Stress-related cardiovascular insufficiency, consequently, depended not only on direct stress but also on the general health condition of the myocardium. Causes and pathogenetic relevance of these alterations are discussed in some detail.
authors.affiliation: Sektion Tierproduktion und Veterinärmedizin, Humboldt-Universität zu Berlin.
authors.forename: V
authors.initials: V
authors.lastname: Bergmann
authors.forename: A
authors.initials: A
authors.lastname: Gräfe
authors.forename: H
authors.initials: H
authors.lastname: Seifert
mesh_terms: D000208:Acute Disease; D000818:Animals; D002318:Cardiovascular Diseases / Q000150:complications / Q000473:pathology / Q000662:veterinary*; D009206:Myocardium / Q000473:pathology*; D013312:Stress, Physiological / Q000150:complications / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000473:pathology*; D014186:Transportation
vernacular_title: Untersuchungen zur Pathomorphologie und Pathogenese des akuten Herz-Kreislauf-Versagens beim Schwein. 3. Mitteilung: Histopathologische Myokardbefunde bei Schweinen mit transportbedingter Herz-Kreislauf-Insuffizienz.