title: Intussusception complicated by bowel perforation during hydrostatic reduction.
abstract: Most perforations of the bowel during attempt at hydrostatic reduction of intussusception occur in an area of localised infarction in the normal transverse or left colon. An animal model of intussusception was used to find indications for the cause of this phenomenon. We submitted the intussuscipiens of 10 strangulated intussusceptions in 6 dogs to a histological examination. In 6 of 10 intussusceptions we found ischaemic changes in the mucosa of the intussuscipiens. In 3 cases these lesions were multiple. All lesions were found in locations where there was a close contact between the intussusceptum and the intussuscipiens. We did not find signs of impaired circulation of the whole intussuscipiens. We conclude that our findings give an indication that perforation of the intussuscipiens during attempt at hydrostatic reduction occurs through areas of localised ischaemic infarction on the basis of direct pressure by the intussusceptum.
authors.affiliation: Department of General Surgery, University Hospital St. Radboud, Nijmegen, The Netherlands.
authors.forename: J A
authors.initials: JA
authors.lastname: Reijnen
authors.forename: M
authors.initials: M
authors.lastname: Mravunac
authors.forename: C
authors.initials: C
authors.lastname: Festen
mesh_terms: D000818:Animals; D003106:Colon / Q000473:pathology; D004285:Dogs; D005260:Female; D006801:Humans; D006874:Hydrostatic Pressure; D007077:Ileal Diseases / Q000473:pathology / Q000628:therapy*; D007223:Infant; D007238:Infarction / Q000473:pathology; D007413:Intestinal Mucosa / Q000098:blood supply / Q000293:injuries* / Q000473:pathology; D007416:Intestinal Perforation / Q000473:pathology / Q000601:surgery*; D007443:Intussusception / Q000473:pathology / Q000628:therapy*