Circadian rhythm disturbances in neurological patients with chronic hypothermia.
1) We investigated the circadian rhythms of BT and sleep-wakefulness in 8 neurological patients who showed chronic low BT. Their etiologies were varied. 2) Their thyroid functions were normal, but their hypothalamic functions were disturbed endocrinologically to various degrees. 3) Their temperature-elevation system was able to function when they suffered from infectious disease. 4) Six patients had circadian rhythm disturbances of BT and sleep-wakefulness. This fact suggests that there is a close relationship of BT regulation and control of its rhythm, and also a close association of 2 pacemakers, namely, that of sleep-wakefulness and that of BT.
Shinozaki
M
M
Department of Pediatrics, Metropolitan Medical Center for the Severely Handicapped, Tokyo, Japan.
Inoue
Y
Y
Ishizaki
A
A
Sasaki
H
H
D000328:Adult; D001833:Body Temperature Regulation / Q000502:physiology; D001921:Brain / Q000000981:diagnostic imaging / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D002940:Circadian Rhythm / Q000502:physiology*; D005260:Female; D013006:Growth Hormone / Q000378:metabolism; D006801:Humans; D007035:Hypothermia / Q000150:complications / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D012890:Sleep / Q000502:physiology; D013972:Thyrotropin / Q000378:metabolism; D014057:Tomography, X-Ray Computed
D013972:Thyrotropin; D013006:Growth Hormone