[The immune status of children in foci of measles infection studied by an immunoenzyme method].
Children immunized with live measles vaccine in the foci of measles infection varying in intensity (1-9 cases per focus) have been subjected by two methods: the hemagglutination inhibition (HAI) test and the enzyme immunoassay (EIA). As shown in this study, in most cases (98% of all blood serum samples) the correlation between the results of the HAI test and EIA is not high (r = 0.5), which is linked with the detection of a wider spectrum of antibodies in EIA. The percentage of seronegative children detected by these two methods was practically the same (4.05 and 4.4, respectively). The analysis of the results obtained in this study indicates that EIA is a more informative and sensitive method, which confirms the effectiveness of its use for the determination of the level of collective immunity.
Iuminova
N V
NV
Unanov
S S
SS
Krasnova
V P
VP
Malancheva
O A
OA
Kovaleva
L G
LG
Liashenko
V A
VA
D000914:Antibodies, Viral / Q000097:blood; D002648:Child; D004197:Disease Reservoirs; D005069:Evaluation Studies as Topic; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D007124:Immunoenzyme Techniques; D008457:Measles / Q000453:epidemiology / Q000276:immunology* / Q000517:prevention & control; D008458:Measles Vaccine / Q000276:immunology; D008459:Measles virus / Q000276:immunology; D016036:Seroepidemiologic Studies
D000914:Antibodies, Viral; D008458:Measles Vaccine
Izuchenie immunnogo statusa deteĭ v ochagakh korevoĭ infektsii metodom IFA.