Identification of SIV/SMM viral proteins that induce T cell response in experimentally infected rhesus macaques and naturally infected sooty mangabeys by the cellular western blot assay.
Initial studies have revealed subtle differences in the T cell proliferative response to whole SIV antigen in the peripheral blood mononuclear cells (PBMC) from sooty mangabeys and rhesus macaques. Preliminary findings utilizing the cellular Western blot assay are described.
Powell
J D
JD
Department of Pathology, Winship Cancer Center, Atlanta, GA.
Villinger
F
F
Yehuda-Cohen
T
T
Vuchetich
M
M
McClure
H M
HM
Sell
K W
KW
Ahmed-Ansari
A
A
D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis; D000956:Antigens, Viral / Q000276:immunology; D015153:Blotting, Western; D002520:Cercopithecidae; D008213:Lymphocyte Activation; D008253:Macaca mulatta; D012191:Retroviridae Proteins / Q000276:immunology*; D016097:Simian Acquired Immunodeficiency Syndrome / Q000276:immunology*; D015302:Simian Immunodeficiency Virus / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
D000914:Antibodies, Viral; D000956:Antigens, Viral; D012191:Retroviridae Proteins