Raised dopamine metabolites in a case of malignant paraganglioma.
This paper describes the case of a malignant retroperitoneal paraganglioma with extensive metastases. The patient presented with a supraclavicular mass and an absence of hypertension. Exclusively raised dopamine metabolites were detected which may be a marker of a malignant process and account for the lack of hypertension.
Florkowski
C M
CM
Department of Clinical Chemistry, New Cross Hospital, Wolverhampton, UK.
Fairlamb
D J
DJ
Freeth
M G
MG
Taylor
S A
SA
Taylor
A
A
Weinkove
C
C
Jacobs
A G
AG
D000328:Adult; D014408:Biomarkers, Tumor / Q000378:metabolism; D004298:Dopamine / Q000378:metabolism*; D006719:Homovanillic Acid / Q000652:urine; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis; D010235:Paraganglioma / Q000652:urine*; D012186:Retroperitoneal Neoplasms / Q000652:urine*; D014642:Vanilmandelic Acid / Q000652:urine
D014408:Biomarkers, Tumor; D014642:Vanilmandelic Acid; D004298:Dopamine; D006719:Homovanillic Acid