[The indices of antipneumococcal immunity in children with chronic pneumonia].
In 76 children with chronic pneumonia the levels of serum antibodies to pneumococcal capsular polysaccharide antigens (serotypes 1, 3, 6B, 8, 9N, 15F, 23F), O-polysaccharide and pneumococcal protein somatic antigens were determined by ELISA techniques. The study showed that in sick children the content of antipneumococcal antibodies in the blood increased with age. No correlation between the content of total immunoglobulins and that of antipneumococcal antibodies in the blood of the patients was established, but a sharp decrease in the concentration of antibodies was registered in a child with hypoglobulinemia. No increase in the level of antibodies to pneumococcal antigens was observed in cases of the exacerbation of Pneumococcus-induced inflammatory process in the lungs.
Ulanova
M A
MA
Padiukov
L N
LN
Volkov
I K
IK
Katosova
L K
LK
Sidorina
T M
TM
Sapargel'dyev
A
A
D000293:Adolescent; D000907:Antibodies, Bacterial / Q000097:blood*; D000917:Antibody Formation / Q000276:immunology; D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007223:Infant; D008297:Male; D011018:Pneumonia, Pneumococcal / Q000276:immunology* / Q000382:microbiology; D011135:Polysaccharides, Bacterial / Q000276:immunology; D013183:Sputum / Q000382:microbiology; D013296:Streptococcus pneumoniae / Q000276:immunology* / Q000302:isolation & purification
D000907:Antibodies, Bacterial; D007136:Immunoglobulins; D011135:Polysaccharides, Bacterial
Pokazateli protivopnevmokokkovogo immuniteta u deteĭ, bol'nykh khronicheskoĭ pnevmonieĭ.