Resistance of congenitally immunodeficient gnotobiotic mice to vaginal candidiasis.
Congenitally immunodeficient beige, athymic, and beige athymic mice whose orogastric mucosal tissues were chronically colonized and infected with a pure culture of Candida albicans were found to be resistant to naturally occurring vulvovaginal candidiasis.
Cantorna
M
M
Department of Medical Microbiology and Immunology, University of Wisconsin Medical School, Madison 53706.
Mook
D
D
Balish
E
E
D000818:Animals; D002181:Candidiasis, Vulvovaginal / Q000276:immunology / Q000382:microbiology* / Q000473:pathology; D005260:Female; D005753:Gastric Mucosa / Q000382:microbiology; D005856:Germ-Free Life; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000382:microbiology* / Q000473:pathology; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude