Wilson's disease presenting as acute fulminant hepatic failure.
A fatal case of fulminant hepatic failure in an adolescent is described. Post-mortem examination revealed the cause to be Wilson's Disease. This rare presentation is characterised by apparently atypical changes in copper metabolism. Wilson's Disease should be a differential diagnosis of any adolescent presenting in liver failure.
O'Donnell
J G
JG
Institute of Clinical Biochemistry, Glasgow Royal Infirmary.
Watson
I D
ID
Fell
G S
GS
Allison
M E
ME
Russell
R I
RI
Mills
P R
PR
D000293:Adolescent; D003300:Copper / Q000097:blood; D005190:Family; D005260:Female; D006527:Hepatolenticular Degeneration / Q000175:diagnosis*; D006801:Humans; D008107:Liver Diseases / Q000209:etiology*
D003300:Copper