title: Malignant potential of juvenile polyposis coli. Report of a case and review of the literature.
abstract: Juvenile polyps of the colon and rectum traditionally have been viewed as being benign inflammatory or harmartomatous lesions without potential for malignant change. The authors report a case of adenocarcinoma developing in a patient with sporadic juvenile polyposis. Juvenile polyposis was diagnosed in the patient at age 4 years. He underwent subtotal colectomy at age 6 years. At age 12, he underwent a proctectomy and a Swenson pull-through because of adenomatous changes in the rectal stump. At age 19 surveillance endoscopy revealed invasive cancer in a juvenile polyp.
authors.affiliation: Department of Surgery, Yale New Haven Hospital, Yale University School of Medicine, Connecticut.
authors.forename: W E
authors.initials: WE
authors.lastname: Longo
authors.forename: R J
authors.initials: RJ
authors.lastname: Touloukian
authors.forename: A B
authors.initials: AB
authors.lastname: West
authors.forename: G H
authors.initials: GH
authors.lastname: Ballantyne
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000328:Adult; D002471:Cell Transformation, Neoplastic; D002675:Child, Preschool; D003111:Colonic Polyps / Q000473:pathology* / Q000601:surgery; D015179:Colorectal Neoplasms / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000473:pathology*