title: [Primary biliary cirrhosis--analysis of clinical material].
abstract: The analysis is presented of 67 patients with primary biliary cirrhosis treated in the years 1971-1988. The group consisted of 60 women (89.5%) and seven men (10.5%). Presenting symptoms were mostly itching (66%) and jaundice (12%). The time between the onset of the first symptoms and the diagnosis was three years, on the average. Autoantibodies to mitochondria were present in 86% of patients. In 27% of cases markers of HB virus infection were found. Cholelithiasis was present in 19 patients (28%). Primary biliary cirrhosis was diagnosed with delay. Third degree of histological changes was observed in 38.8% of cases and in 18% of patients it was already fourth degree. Eighteen patients (27%) died after six years, on the average, from the onset of symptoms. The direct causes of death were, most frequently, liver failure and haemorrhage from oesophageal varices.
authors.affiliation: Kliniki Gastroneterologii i Przemiany Materii CMKP w Warszawie.
authors.forename: A
authors.initials: A
authors.lastname: Habior
authors.forename: B
authors.initials: B
authors.lastname: Milewski
authors.forename: W
authors.initials: W
authors.lastname: Medrzejewski
authors.forename: T
authors.initials: T
authors.lastname: Nazarewicz
authors.forename: A
authors.initials: A
authors.lastname: Gugulski
mesh_terms: D000328:Adult; D000368:Aged; D001323:Autoantibodies / Q000032:analysis; D005260:Female; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000175:diagnosis* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D008928:Mitochondria / Q000276:immunology; D015996:Survival Rate
chemical_list: D001323:Autoantibodies
vernacular_title: Pierwotna zółciowa marskość watroby--analiza materiałlu klinicznego.