title: Eosinophilia-myalgia syndrome (L-tryptophan-associated neuromyopathy).
abstract: Histopathologic study of skeletal muscle biopsy in a patient with eosinophilia-myalgia syndrome following L-tryptophan use showed prominent lymphocytic perineuritis, neuritis, and perimysial fasciitis. The presence of perineuritis and neuritis provides a histopathologic basis for clinical features of neuropathy in eosinophilia-myalgia syndrome and occurred in conjunction with a fasciitis or interstitial myositis that was predominantly perimysial and focally endomysial.
authors.affiliation: Department of Pathology, Winthrop-University Hospital, Mineola, NY 11501.
authors.forename: G K
authors.initials: GK
authors.lastname: Turi
authors.forename: G B
authors.initials: GB
authors.lastname: Solitare
authors.forename: N
authors.initials: N
authors.lastname: James
authors.forename: R
authors.initials: R
authors.lastname: Dicker
mesh_terms: D001706:Biopsy; D004802:Eosinophilia / Q000139:chemically induced*; D005208:Fasciitis / Q000139:chemically induced / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009132:Muscles / Q000473:pathology; D009220:Myositis / Q000139:chemically induced* / Q000473:pathology / Q000503:physiopathology; D009443:Neuritis / Q000139:chemically induced* / Q000473:pathology; D010146:Pain / Q000139:chemically induced*; D013577:Syndrome; D014364:Tryptophan / Q000009:adverse effects*
chemical_list: D014364:Tryptophan