Squamous cell carcinoma-antigen for detection of squamous cell and mucoepidermoid carcinoma after primary treatment: a preliminary report.
This study evaluated the efficacy of using the periodic measurement of the serum level of squamous cell carcinoma antigen (SCC-antigen) for determining the local recurrence and/or metastasis of squamous cell and mucoepidermoid carcinomas after primary treatment. It was found that at the time of clinical recognition of recurrence, the SCC-antigen level was normal, but metastasis to regional lymph nodes or to remote organs generally was accompanied by an increase of SCC-antigen. Changes in the SCC-antigen level with mucoepidermoid carcinoma seemed to be less sensitive than with squamous cell carcinoma.
Yoshimura
Y
Y
Department of Oral and Maxillofacial Surgery, Shimane Medical University, Japan.
Oka
M
M
Harada
T
T
D000368:Aged; D000951:Antigens, Neoplasm / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood; D002277:Carcinoma / Q000175:diagnosis / Q000276:immunology / Q000556:secondary / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000276:immunology* / Q000556:secondary / Q000628:therapy; D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000276:immunology* / Q000556:secondary / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000276:immunology; D011379:Prognosis
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor