title: [A new diterpenoid quinone sapriparaquinone].
abstract: A new diterpenoid quinone, named sapriparaquinone (1) was isolated from the root of Salvia prionitis Hance. 1 was identified as 3-hydroxy-6-methyl-2-(1-methyl)-5-(4-methylpenten-3-yl)-1, 4-naphthoquinone by spectral analysis and chemical transformation of saprorthquinone (2). 1 and 2 are 4,5-seco-5, 10-frideoabietane derivatives and must be biogenetically derived from an abietane structure. Like 2, 1 also showed cytotoxicity against P388 leukemia cells.
authors.affiliation: Shangai Institute of Materia Medica, Chinese Academy of Sciences.
authors.forename: L Z
authors.initials: LZ
authors.lastname: Lin
authors.forename: X M
authors.initials: XM
authors.lastname: Wang
authors.forename: X L
authors.initials: XL
authors.lastname: Huang
authors.forename: Y
authors.initials: Y
authors.lastname: Huang
mesh_terms: D000818:Animals; D055598:Chemical Phenomena; D002621:Chemistry; D004224:Diterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000032:analysis*; D007941:Leukemia P388 / Q000473:pathology; D051379:Mice; D009285:Naphthoquinones / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured / Q000187:drug effects
chemical_list: D004224:Diterpenes; D004365:Drugs, Chinese Herbal; D009285:Naphthoquinones; C066123:sapriparaquinone