title: Exaggerated reaction to insect bites in patients with chronic lymphocytic leukemia. Clinical and histological findings.
abstract: We report three patients with chronic lymphocytic leukemia with unusual vesiculo-bullous skin eruptions on exposed areas which were more commonly noted in spring and summer. The lesions appeared to be due to insect bites and could be differentiated from other causes on the basis of histological, immunohistological and clinical features. There was no correlation between the occurrence of the skin eruptions, disease status and treatment modalities. Exaggerated cutaneous reaction to insect bites should be considered as a cause of vesiculo-bullous lesions in patients with chronic lymphocytic leukemia.
authors.affiliation: Department of Anatomical Pathology, Alfred Hospital, Melbourne.
authors.forename: J
authors.initials: J
authors.lastname: Pedersen
authors.forename: J
authors.initials: J
authors.lastname: Carganello
authors.forename: M B
authors.initials: MB
authors.lastname: van der Weyden
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D005260:Female; D005455:Fluorescent Antibody Technique; D006801:Humans; D007124:Immunoenzyme Techniques; D007299:Insect Bites and Stings / Q000150:complications* / Q000473:pathology*; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications*; D008297:Male; D008875:Middle Aged