There are two major types of skeletal keratan sulphates.
High-field 1H-n.m.r.-spectroscopic studies supported by chemical carbohydrate analyses show that skeletal keratan sulphates (KS-II) of bovine origin may be sub-classified into two groups. Keratan sulphate chains from articular and intervertebral-disc cartilage (KS-II-A) contain two structural features, namely alpha(1----3)-fucose and alpha(2----6)-linked N-acetyl-neuraminic acid residues, that are absent from keratan sulphates from tracheal or nasal-septum cartilage (KS-II-B).
Nieduszynski
I A
IA
Division of Biological Sciences, University of Lancaster, Bailrigg, U.K.
Huckerby
T N
TN
Dickenson
J M
JM
Brown
G M
GM
Tai
G H
GH
Morris
H G
HG
Eady
S
S
D000818:Animals; D002236:Carbohydrate Conformation; D002356:Cartilage / Q000737:chemistry*; D002358:Cartilage, Articular / Q000737:chemistry; D002417:Cattle; D005643:Fucose / Q000032:analysis; D005690:Galactose / Q000032:analysis; D007403:Intervertebral Disc / Q000737:chemistry; D007632:Keratan Sulfate / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D019158:N-Acetylneuraminic Acid; D009300:Nasal Septum / Q000737:chemistry; D012794:Sialic Acids / Q000032:analysis; D014132:Trachea / Q000737:chemistry
D012794:Sialic Acids; D005643:Fucose; D007632:Keratan Sulfate; D019158:N-Acetylneuraminic Acid; D005690:Galactose