title: Glutamine nutrition: theoretical considerations and therapeutic impact.
abstract: In critically ill surgical patients, nutritional therapy is an important component of overall care. As our knowledge increases, "tailor-made" diets designed to meet specific nutritional requirements in specific patients may play an important role. Although the data reviewed here suggest that glutamine-supplemented diets may have a significant impact in some clinical settings, it should be emphasized that additional carefully designed studies are necessary before the use of glutamine-enriched nutrition in critically ill patients should be advocated. It is clear, however, that the concept that the intestine is an organ of inactivity during critical illness merits reconsideration.
authors.affiliation: Department of Surgery, University of Florida College of Medicine, Gainesville 32610.
authors.forename: W W
authors.initials: WW
authors.lastname: Souba
authors.forename: K
authors.initials: K
authors.lastname: Herskowitz
authors.forename: T R
authors.initials: TR
authors.lastname: Austgen
authors.forename: M K
authors.initials: MK
authors.lastname: Chen
authors.forename: R M
authors.initials: RM
authors.lastname: Salloum
mesh_terms: D000818:Animals; D004064:Digestive System / Q000187:drug effects*; D005973:Glutamine / Q000494:pharmacology* / Q000502:physiology; D006801:Humans; D007107:Immune System / Q000187:drug effects; D008168:Lung / Q000187:drug effects; D009132:Muscles / Q000187:drug effects
chemical_list: D005973:Glutamine