title: [The effect of chronic exposure to lead on lysosomal levels in amniotic fluid in an experimental model].
abstract: Groups of female rats were exposed for prolonged periods to different lead concentrations in drinking water; in one group was also added to the drinking water, in the amniotic fluid of exposed females greatly reduced lysozyme values were found, as compared with controls. Concurrent Zn administration considerably reduced the effect of lead. Long-term exposure to low concentrations of lead caused a greater drop of lysozyme levels in amniotic fluid than that found in previous experiments after short-term exposure to higher lead concentration.
authors.affiliation: Fyziologický ústav CSAV, Praha.
authors.forename: I
authors.initials: I
authors.lastname: Pfeifer
authors.forename: J
authors.initials: J
authors.lastname: Richter
authors.forename: Z
authors.initials: Z
authors.lastname: Deyl
authors.forename: J
authors.initials: J
authors.lastname: Hausman
mesh_terms: D000653:Amniotic Fluid / Q000201:enzymology*; D000818:Animals; D005260:Female; D007855:Lead Poisoning / Q000201:enzymology*; D009113:Muramidase / Q000378:metabolism*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000201:enzymology*; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D009113:Muramidase
vernacular_title: Vliv chronické expozice olovu na hladinu lysozymu v plodové vodĕ v modelovém pokuse.