[The value of high dose steroid therapy in obstructive uropathy caused by a tumor].
The case of an 82-years old female patient with acute renal failure secondary to tumoral obstructive uropathy by neoplasic invasion of the trigone is described. The condition was treated with urinary deviation through percutaneous nephrostomy of the left kidney which achieved an improvement in the renal function. Later, the percutaneous nephrostomy was unintentionally moved not being possible to place a new one in none of the kidneys. The patient remained anuric for 24 hours, and therapy was then instaured with high doses of intravenous steroids (6 Metyl-Prednisolone 1.5 g I.V. in 24 hours), diuresis was recovered and renal function became normalized within a few days. The mechanism of action and therapeutic usefulness of high dosage steroids in tumoral obstructive pathology is discussed.
Hernández
E
E
Servicio de Nefrología, Hospital 12 de Octubre, Madrid.
Gutierres-Millet
V
V
Díaz-González
R
R
Rodríguez
A
A
Moreno
F
F
Rodicio
J L
JL
Bello
I
I
D000368:Aged; D000369:Aged, 80 and over; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007682:Kidney Pelvis / Q000601:surgery; D008775:Methylprednisolone / Q000008:administration & dosage* / Q000627:therapeutic use; D014463:Ultrasonography; D014516:Ureteral Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery; D014517:Ureteral Obstruction / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D014547:Urinary Diversion
D008775:Methylprednisolone
Utilidad del tratamiento con dois altas de esteroides en la uropatía obstructiva tumoral.