Acne keloidalis-like lesions on the scalp associated with antiepileptic drugs.
A man developed acne keloidalis-like lesions in the scalp during treatment with diphenylhydantoin and carbamazepine for epilepsy. These drugs were suspected to play a role in the pathogenesis of this skin disease in an unusual location, based on clinical evidence and on the in vitro test, mast cell degranulation (MCD).
Grunwald
M H
MH
Department of Dermatology and Pathology, Soroka University Hospital, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Ben-Dor
D
D
Livni
E
E
Halevy
S
S
D000153:Acne Keloid / Q000139:chemically induced* / Q000473:pathology; D000328:Adult; D002220:Carbamazepine / Q000009:adverse effects*; D004827:Epilepsy / Q000188:drug therapy; D006801:Humans; D008297:Male; D010672:Phenytoin / Q000009:adverse effects*; D012536:Scalp Dermatoses / Q000139:chemically induced* / Q000473:pathology
D002220:Carbamazepine; D010672:Phenytoin