title: Amino acid sequence around the pyridoxal 5'-phosphate binding site of rat liver L-threonine deaminase.
abstract: Rat liver L-threonine deaminase is a pyridoxal 5'-phosphate dependent enzyme. In the present study we have studied the amino acid sequence composition of the peptide surrounding the coenzyme binding lysine at the active site of the native enzyme. We have also examined the homology between this peptide and the analogue forms of L-threonine deaminase from different sources.
authors.affiliation: Istituto di Chimica Biologica, Università, Siena.
authors.forename: R
authors.initials: R
authors.lastname: Leoncini
authors.forename: A
authors.initials: A
authors.lastname: Henschen
authors.forename: K
authors.initials: K
authors.lastname: Krieglstein
authors.forename: J
authors.initials: J
authors.lastname: Calvete
authors.forename: R
authors.initials: R
authors.lastname: Pagani
authors.forename: E
authors.initials: E
authors.lastname: Marinello
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D008099:Liver / Q000201:enzymology; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000032:analysis; D011732:Pyridoxal Phosphate / Q000378:metabolism; D051381:Rats; D013913:Threonine Dehydratase / Q000737:chemistry*
chemical_list: D010446:Peptide Fragments; D011732:Pyridoxal Phosphate; D013913:Threonine Dehydratase