Neurogenesis of respiratory rhythm and pattern: emerging concepts.
We present three hypotheses related to the nervous system control of breathing in mammals: 1) that neural mechanisms controlling breathing change with state and that the relationship between mechanisms in different states can be described in terms of either modulation or a basic transformation of properties, or both; 2) that the mechanisms generating respiratory rhythm and pattern are separate; and 3) that conditional pacemaker cell activity is the basis for respiratory rhythm in highly reduced states.
Feldman
J L
JL
Department of Kinesiology, University of California, Los Angeles 90024-1527.
Smith
J C
JC
Ellenberger
H H
HH
Connelly
C A
CA
Liu
G S
GS
Greer
J J
JJ
Lindsay
A D
AD
Otto
M R
MR
D000818:Animals; D006801:Humans; D008954:Models, Biological; D009424:Nervous System Physiological Phenomena; D009433:Neural Inhibition; D012119:Respiration; D013569:Synapses / Q000502:physiology