title: 585 nm for the treatment of port-wine stains.
abstract: Although the flashlamp-pulsed-dye laser has been successfully used for the treatment of port-wine stains (PWS) at 577 nm, a number of adult patients had incomplete clearance of their birthmarks with this treatment modality because of residual vessels lying beyond the 0.75-mm penetration depth of 577-nm irradiation. Fifteen adult patients, of whom nine were previously treated with limited success at 577 nm (group A), and six untreated patients (group B) were included in the study. For the group A patients, treatment with 585 nm produced successful clearance of the birthmark. For the six patients in group B, parallel treatment of different sites of the same lesion coupled with skin biopsies and histologic examination revealed that a change in the wavelength from 577 to 585 nm allowed the laser light to penetrate from the midreticular dermis into the subcutaneous fat. This explained the clearance achieved at 585 nm and not at 577 nm.
authors.affiliation: Department of Dermatology, Boston University Medical Center, Mass.
authors.forename: O T
authors.initials: OT
authors.lastname: Tan
authors.forename: P
authors.initials: P
authors.lastname: Morrison
authors.forename: A K
authors.initials: AK
authors.lastname: Kurban
mesh_terms: D000293:Adolescent; D000328:Adult; D005153:Facial Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D006391:Hemangioma / Q000473:pathology / Q000601:surgery*; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D008297:Male