title: [24-hour blood pressure measurement in normal pregnancy in hypertensive pregnant patients].
abstract: Noninvasive 24-hour ambulatory blood pressure monitoring was performed in 17 normotensive and 19 preeclamptic pregnant women. The normotensive women showed a significant nightly decline in their systolic and diastolic blood pressure. In contrast, the preeclamptic women demonstrated either an attenuated circadian rhythm or no circadian rhythm at all. This result was even more pronounced in patients with severe hypertension, some of whom had a nocturnal increase in blood pressure in spite of being treated with antihypertensive drugs in an evening dose. The lack of nocturnal blood pressure decrease was also found 24 hours post partum. In summary, these results suggest that preeclamptic women are endangered by hypertensive emergencies mostly during the night. Therefore blood pressure controls should be extended into the night, and antihypertensive drugs should also be given in a sufficient evening dose.
authors.affiliation: Universitätsfrauenklinik Göttingen.
authors.forename: W
authors.initials: W
authors.lastname: Rath
authors.forename: J
authors.initials: J
authors.lastname: Schrader
authors.forename: U
authors.initials: U
authors.lastname: Guhlke
authors.forename: H
authors.initials: H
authors.lastname: Buhr-Schinner
authors.forename: A
authors.initials: A
authors.lastname: Haupt
authors.forename: A
authors.initials: A
authors.lastname: Kramer
authors.forename: W
authors.initials: W
authors.lastname: Kuhn
mesh_terms: D001794:Blood Pressure / Q000187:drug effects; D015924:Blood Pressure Monitors; D002940:Circadian Rhythm / Q000502:physiology*; D004078:Dihydralazine / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007260:Infusion Pumps; D008790:Metoprolol / Q000008:administration & dosage; D011225:Pre-Eclampsia / Q000175:diagnosis* / Q000188:drug therapy; D011247:Pregnancy
chemical_list: D008790:Metoprolol; D004078:Dihydralazine
vernacular_title: 24-Stunden-Blutdruckmessungen im Verlauf der normalen Schwangerschaft und bei hypertensiven Schwangeren.