The mechanism of acquired immunity in experimental giardiasis.
Giardia-spontaneously cured mice were rendered resistant to challenge infection. This was documented by the decreased cyst excretion rate comparable to the control ones. Endoxan and irradiation treatment caused a breakdown in both humoral and cellular immunity. Immune-depressed mice were more susceptible to Giardia infection, thus proving the active role of antibodies and cell-mediated immune response in giardiasis.
Romia
S A
SA
Department of Parasitology, Faculty of Medicine, Mansoura University, Egypt.
Abou-Zakham
A A
AA
Hegazi
M M
MM
D000818:Animals; D000913:Antibodies, Protozoan / Q000096:biosynthesis; D005872:Giardia / Q000276:immunology; D005873:Giardiasis / Q000276:immunology*; D006801:Humans; D007110:Immunity, Active; D007111:Immunity, Cellular; D007165:Immunosuppression Therapy; D051379:Mice
D000913:Antibodies, Protozoan