title: The effect of copper on the embryonic development and hatching of Sepia officinalis L.
abstract: The influence of copper on embryonic development and hatching of Sepia offinalis was investigated. Copper exerts a profound effect on both hatching stage and time-to-hatching. At high copper concentrations (50-200 ppb Cu2+), the embryos hatch earlier than the controls but have a lower survival potential. No external morphological malformations were found. Whereas copper does not accumulate in the embryo or in the vitellus, it is absorbed by the envelope and/or the chorion.
authors.affiliation: Zoology Department I, Catholic University, Toernooiveld, Nijmegen, The Netherlands.
authors.forename: W P
authors.initials: WP
authors.lastname: Paulij
authors.forename: W
authors.initials: W
authors.lastname: Zurburg
authors.forename: J M
authors.initials: JM
authors.lastname: Denucé
authors.forename: E J
authors.initials: EJ
authors.lastname: van Hannen
mesh_terms: D000818:Animals; D003300:Copper / Q000633:toxicity*; D004625:Embryo, Nonmammalian / Q000187:drug effects / Q000502:physiology; D008974:Mollusca / Q000196:embryology / Q000502:physiology*
chemical_list: D003300:Copper