title: [A case of hybrid acute leukemia in a a child].
abstract: Hybrid acute leukaemia is characterized by the presence of lymphoid and myeloid markers in a single cell or in different blast cell subpopulations of the same patient. Authors report on a case of a 14-yr-old girl with hybrid acute leukaemia. Immunofluorescent analysis revealed CD 14, CD 10, CD 19 and HLA-DR antigens in the cell suspension isolated from peripheral blood of the patient. Because of the excess of FAB M1 type blast cells, the patient was treated according to IGCI-1984 protocol. Remission was not achieved despite combined cytotoxic treatment and patient died within 4 weeks following admission. The poor outcome of the disease agrees well with literature data. Hybrid acute leukaemia represents a challenge for the clinical science.
authors.affiliation: Gyermekgyógyászati Klinika, Debreceni Orvostudományi Egyetem.
authors.forename: C
authors.initials: C
authors.lastname: Kiss
authors.forename: A
authors.initials: A
authors.lastname: Kiss
authors.forename: I
authors.initials: I
authors.lastname: Kovács
authors.forename: E
authors.initials: E
authors.lastname: Oláh
authors.forename: E
authors.initials: E
authors.lastname: Balogh
authors.forename: L
authors.initials: L
authors.lastname: Karmazsin
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols; D003582:Cytogenetics; D006801:Humans; D007150:Immunohistochemistry; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000628:therapy; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000628:therapy
vernacular_title: Hybrid acut leukaemias gyermek esete.