title: [Extracardial manifestations in constrictive pericarditis].
abstract: Constrictive pericarditis is a slowly progressive disabling disease. The diagnosis is easily overlooked because of the striking extracardial signs and symptoms such as abdominal discomfort, general fatigue, cachexia, ascites and oedema. We describe 7 patients with these symptoms in whom the diagnosis was missed during 0.5-17 years. The decisive clue for correct diagnosis appeared to be the raised central venous pressure. This proves the importance of an accurate physical examination. Other findings were: ascites (7/7), hepatomegaly (7/7), oedema (6/7), narrow pulse pressure (less than or equal to 35 mmHg) (5/7), ECG abnormalities (7/7) and pericardial calcifications on the chest X-ray (5/7). In addition we found slightly raised liver enzymes and a protein-losing enteropathy leading to low serum protein levels. These abnormalities are all explained by the alterations in haemodynamics and lymph flow. The only curative therapy is surgical decortication of the heart.
authors.affiliation: Afd. Maag-, darm- en leverziekten, Sint-Radboudziekenhuis, Nijmegen.
authors.forename: M
authors.initials: M
authors.lastname: van Deuren
authors.forename: W H
authors.initials: WH
authors.lastname: Hoefenagels
authors.forename: U G
authors.initials: UG
authors.lastname: van Haelst
authors.forename: K
authors.initials: K
authors.lastname: van Leeuwen
authors.forename: S H
authors.initials: SH
authors.lastname: Skotnicki
authors.forename: J H
authors.initials: JH
authors.lastname: van Tongeren
mesh_terms: D000328:Adult; D000368:Aged; D001201:Ascites / Q000209:etiology; D003951:Diagnostic Errors; D004417:Dyspnea / Q000209:etiology; D004487:Edema / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010494:Pericarditis, Constrictive / Q000150:complications* / Q000175:diagnosis / Q000601:surgery
vernacular_title: De extracardiale verschijnselen bij pericarditis constrictiva.