title: [In situ hybridization: principles, methods and applications].
abstract: In situ hybridization is used to localize DNA or RNA sequences in tissue sections, single cells or chromosome preparations. The preparation and labeling of probes and the main steps of the technique are described and discussed together with its main applications.
authors.affiliation: Laboratoire d'Anatomie Pathologique, Faculté de Médecine, Vandceuvre-Lès-Nancy, France.
authors.forename: J M
authors.initials: JM
authors.lastname: Vignaud
authors.forename: F
authors.initials: F
authors.lastname: Plenat
authors.forename: A
authors.initials: A
authors.lastname: Duprez
mesh_terms: D001483:Base Sequence; D006801:Humans; D008722:Methods; D008969:Molecular Sequence Data; D009693:Nucleic Acid Hybridization; D015341:Nucleic Acid Probes; D012333:RNA, Messenger / Q000302:isolation & purification; D014777:Virus Diseases / Q000382:microbiology
chemical_list: D015341:Nucleic Acid Probes; D012333:RNA, Messenger
vernacular_title: L'hybridation in situ: principes, méthodes et applications.