title: [Cerebral insufficiency--treatment with Ginkgo-biloba extract. Time of onset of effect in a double-blind study with 60 inpatients].
abstract: Sixty inpatients with cerebral insufficiency and the leading symptom depressive mood, were treated in a double-blind study for 6 weeks with a daily dose of 160 mg Ginkgo biloba extract or placebo. After 2, 4 and 6 weeks, changes in 12 typical symptoms in comparison with the last examination, were evaluated. In the group receiving placebo, small, but progressive improvements were observed. In the Ginkgo-biloba group, the overall number of improvements was significantly larger. After 2 weeks the differences were marked for only a few of the symptoms; after 4 and 6 weeks in contrast, in 11 of the 12 symptoms. The largest number of improvements in the Ginkgo-biloba group was observed between the 2nd and 4th weeks of treatment. In this period, about two-thirds of the patients on Ginkgo-biloba, and about one-fifth of the patients on placebo showed improvements.
authors.affiliation: Landeskrankenhaus Schleswig.
authors.forename: F
authors.initials: F
authors.lastname: Eckmann
mesh_terms: D000328:Adult; D000368:Aged; D001007:Anxiety / Q000188:drug therapy; D001288:Attention / Q000187:drug effects; D002561:Cerebrovascular Disorders / Q000188:drug therapy*; D003863:Depression / Q000188:drug therapy*; D004311:Double-Blind Method; D005260:Female; D020441:Ginkgo biloba; D006261:Headache / Q000188:drug therapy; D006801:Humans; D008297:Male; D008568:Memory / Q000187:drug effects; D008875:Middle Aged; D010936:Plant Extracts / Q000627:therapeutic use*; D000096983:Ginkgo Extract
chemical_list: D010936:Plant Extracts; C063170:Ginkgo biloba extract; D000096983:Ginkgo Extract
vernacular_title: Hirnleistungsstörungen--Behandlung mit Ginkgo-biloba-Extrakt. Zeitpunkt des Wirkungseintrits in einer Doppelblindstudie mit 60 stationären Patienten.