[The action of reserpine on cholinergic processes in the heart].
Experiments on white rats show that reserpine creates conditions for acetylcholine accumulation in the heart. In early periods after reserpine administration (within 8 hours) this process depends on restriction of mediator hydrolysis. In more distant periods (within 24 hours) synthesis activation adds to the mentioned mechanism.
Markova
O O
OO
Faĭfura
V V
VV
Vadziuk
S N
SN
Svystun
R V
RV
D000109:Acetylcholine / Q000378:metabolism; D000818:Animals; D002795:Choline O-Acetyltransferase / Q000378:metabolism; D006321:Heart / Q000187:drug effects*; D009206:Myocardium / Q000378:metabolism; D051381:Rats; D011950:Receptors, Cholinergic / Q000187:drug effects* / Q000378:metabolism; D012110:Reserpine / Q000494:pharmacology*; D013997:Time Factors
D011950:Receptors, Cholinergic; D012110:Reserpine; D002795:Choline O-Acetyltransferase; D000109:Acetylcholine
Diia rezerpinu na kholinergichni protsesy v sertdi.