title: [An adult case of malignant choroid plexus papilloma in the lateral ventricle and the cerebellopontine angle revealed simultaneously].
abstract: An adult case of malignant choroid plexus papilloma is very rare. This report is an adult case of malignant choroid plexus papilloma revealed in the lateral ventricle and in the cerebellopontine (CP) angle simultaneously. A 37-year-old man was admitted to the hospital complaining of headache, nausea, and a floating sensation on August 29, 1984. Neurological examination on admission revealed bilateral papilledema, left dysmetria and horizontal nystagmus. CT scan revealed a slightly high density round mass in the right lateral ventricle and a cystic mass with mural nodule in the left CP angle. The intraventricular mass and mural nodule were enhanced moderately and homogeneously. The initial surgery was for removal of the CP angle tumor, and 8 days later removal of the lateral ventricle tumor was carried out. The histology of these tumors was the same and revealed malignant choroid plexus papilloma. Postoperative radiation therapy was carried out 70Gy to the brain (whole brain; 50Gy, focal; 20Gy) and 30Gy to the whole spine. About 2 years later paraparesis, lower cranial nerve palsy, and disturbance of consciousness had progressed gradually. He died of the severe recurrence of the tumor in the brain stem, and multiple dissemination in the spinal cord on September 6, 1987. There was no recurrence of tumor in the right lateral ventricle. This is a very rare case of malignant choroid plexus papilloma which was revealed in both the supra- and infratentorial regions simultaneously. They may have developed independently or they may have arisen through subarachnoid seeding. Radical removal of the tumor is important to prevent recurrence of malignant choroid plexus papilloma.
authors.affiliation: Department of Neurosurgery, Nagoya University School of Medicine.
authors.forename: T
authors.initials: T
authors.lastname: Handa
authors.forename: Y
authors.initials: Y
authors.lastname: Hashizume
authors.forename: N
authors.initials: N
authors.lastname: Mutsuga
authors.forename: I
authors.initials: I
authors.lastname: Takahashi
authors.forename: M
authors.initials: M
authors.lastname: Nishimura
mesh_terms: D000328:Adult; D002528:Cerebellar Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D002530:Cerebellopontine Angle; D002551:Cerebral Ventricle Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D002831:Choroid Plexus; D003131:Combined Modality Therapy; D004806:Ependymoma / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000532:radiotherapy / Q000601:surgery