title: Plasma calcitonin levels in patients with cystic fibrosis.
abstract: Plasma levels of calcitonin were investigated in patients with cystic fibrosis and compared with age- and sex-matched healthy controls. About forty per cent of the cystic fibrosis patients had plasma calcitonin levels that were markedly higher than normal. Elevated levels were found predominantly in female patients. In general, patients with marked pulmonary involvement had high plasma calcitonin levels. Immunoextraction and gel chromatography, carried out on plasma of one of the patients demonstrated monomer-like forms of calcitonin similar to those found in the healthy subjects.
authors.affiliation: Department of Prosthodontics, Karolinska Institutet, Stockholm, Sweden.
authors.forename: G B
authors.initials: GB
authors.lastname: Sagulin
authors.forename: E
authors.initials: E
authors.lastname: Bucht
authors.forename: H
authors.initials: H
authors.lastname: Gilljam
authors.forename: H
authors.initials: H
authors.lastname: Sjöberg
authors.forename: G M
authors.initials: GM
authors.lastname: Roomans
mesh_terms: D000293:Adolescent; D000328:Adult; D000375:Aging / Q000378:metabolism; D002116:Calcitonin / Q000097:blood*; D002648:Child; D002850:Chromatography, Gel; D003550:Cystic Fibrosis / Q000097:blood*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008297:Male; D011863:Radioimmunoassay; D012737:Sex Factors; D013054:Spectrophotometry, Atomic
chemical_list: D002116:Calcitonin