title: Identification of human immunodeficiency virus hybridizing sequences in the peripheral blood of a patient with systemic lupus erythematosus.
abstract: Systemic lupus erythematosus, a multisystemic disorder, is considered a prototype of the autoimmune diseases. Although its cause remains unknown, a viral etiology has been proposed. We report that a rapid and sensitive messenger RNA in situ hybridization technique detected hybridizing sequences to the human immunodeficiency virus type in the peripheral blood cells of a woman with systemic lupus erythematosus in whom the presence of acquired immuno-deficiency syndrome was reasonably excluded.
authors.affiliation: Department of Clinical Immunology and Biological Therapy, University of Texas M. D. Anderson Cancer Center, Houston.
authors.forename: M
authors.initials: M
authors.lastname: Blick
authors.forename: J
authors.initials: J
authors.lastname: Bresser
authors.forename: J L
authors.initials: JL
authors.lastname: Lepe-Zuniga
authors.forename: A
authors.initials: A
authors.lastname: Goodacre
authors.forename: D
authors.initials: D
authors.lastname: Luethke
authors.forename: W R
authors.initials: WR
authors.lastname: Holder
authors.forename: M
authors.initials: M
authors.lastname: Duvic
mesh_terms: D000328:Adult; D015153:Blotting, Western; D004279:DNA, Viral / Q000032:analysis*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005784:Gene Amplification; D015497:HIV-1 / Q000235:genetics*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000382:microbiology*; D009693:Nucleic Acid Hybridization; D012367:RNA, Viral / Q000235:genetics*
chemical_list: D004279:DNA, Viral; D012367:RNA, Viral