title: Massive mediastinal extramedullary hematopoiesis in hereditary spherocytosis: a case report.
abstract: A case of extramedullary hematopoiesis (EMH) with a massive mediastinal mass in a 72-year-old woman with hereditary spherocytosis is reported. Several cases of EMH have been described in nonsplenectomized adults with hereditary spherocytosis, and it is thought to be a consequence of long-term stimulation of erythropoiesis. The exact mechanism remains controversial. EMH should be considered in the differential diagnosis of an asymptomatic paravertebral mass.
authors.affiliation: Hematology Service, Centre Hospitalier Lyon-Sud, Pierre-Benite, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Bastion
authors.forename: B
authors.initials: B
authors.lastname: Coiffier
authors.forename: P
authors.initials: P
authors.lastname: Felman
authors.forename: D
authors.initials: D
authors.lastname: Assouline
authors.forename: J D
authors.initials: JD
authors.lastname: Tigaud
authors.forename: D
authors.initials: D
authors.lastname: Espinouse
authors.forename: P A
authors.initials: PA
authors.lastname: Bryon
mesh_terms: D000368:Aged; D005260:Female; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D013103:Spherocytosis, Hereditary / Q000097:blood* / Q000503:physiopathology