Laser Doppler flowmetry and bone blood flow in an isolated perfused preparation.
A preparation of an isolated bovine forefoot was established which could be perfused with blood at variable rates. A laser Doppler flowmeter probe inserted into the cancellous bone of the metatarsal produced a signal which varied with changes in perfusion rate and oscillated in synchrony with the peristaltic perfusion pump. A stronger laser Doppler signal was obtained when the probe was inserted into a drill hole than when inserted into a hole bored with a guide wire. It appears that laser Doppler flowmetry has potential intraoperative use when the viability of bone is in question.
Handley
R C
RC
University Department of Orthopaedics, Royal Victoria Infirmary, Newcastle Upon Tyne, UK.
Essex
T
T
Pooley
J
J
D000818:Animals; D001842:Bone and Bones / Q000098:blood supply*; D066298:In Vitro Techniques; D007834:Lasers; D012039:Regional Blood Flow