title: Laser Doppler flowmetry and bone blood flow in an isolated perfused preparation.
abstract: A preparation of an isolated bovine forefoot was established which could be perfused with blood at variable rates. A laser Doppler flowmeter probe inserted into the cancellous bone of the metatarsal produced a signal which varied with changes in perfusion rate and oscillated in synchrony with the peristaltic perfusion pump. A stronger laser Doppler signal was obtained when the probe was inserted into a drill hole than when inserted into a hole bored with a guide wire. It appears that laser Doppler flowmetry has potential intraoperative use when the viability of bone is in question.
authors.affiliation: University Department of Orthopaedics, Royal Victoria Infirmary, Newcastle Upon Tyne, UK.
authors.forename: R C
authors.initials: RC
authors.lastname: Handley
authors.forename: T
authors.initials: T
authors.lastname: Essex
authors.forename: J
authors.initials: J
authors.lastname: Pooley
mesh_terms: D000818:Animals; D001842:Bone and Bones / Q000098:blood supply*; D066298:In Vitro Techniques; D007834:Lasers; D012039:Regional Blood Flow