title: [Valproic acid and stupor].
abstract: A patient treated with valproic acid and phenytoin for complex partial epilepsy developed a stupor at therapeutic serum levels of the anti-epileptic agents. A few days after discontinuation of valproic acid, complete recovery occurred. The pathogenic mechanism involved is still obscure.
authors.affiliation: Sint Lucas Ziekenhuis, Afd. Neurologie, Amsterdam.
authors.forename: M J
authors.initials: MJ
authors.lastname: Jongsma
authors.forename: C J
authors.initials: CJ
authors.lastname: Snijders
mesh_terms: D004359:Drug Therapy, Combination; D004833:Epilepsy, Temporal Lobe / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010672:Phenytoin / Q000008:administration & dosage / Q000627:therapeutic use*; D014474:Unconsciousness / Q000139:chemically induced*; D014635:Valproic Acid / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D014635:Valproic Acid; D010672:Phenytoin
vernacular_title: Valproïnezuur en stupor.