title: Tuberculous psoas muscle abscess following chemoprophylaxis with isoniazid in a patient with human immunodeficiency virus infection.
abstract: A 34-year-old man with human immunodeficiency virus infection and disseminated Mycobacterium avium and Mycobacterium intracellulare infection developed a right psoas muscle abscess due to Mycobacterium tuberculosis. The abscess occurred 18 months after completion of a 12-month course of chemoprophylaxis with isoniazid that was given because of a positive reaction with purified protein derivative of tuberculin. The adjacent vertebrae did not appear to be involved. The abscess was drained with a percutaneously inserted catheter, and he received standard antituberculous chemotherapy. Three weeks into therapy, a second drainage with a catheter was required. The isolation of two mycobacteria in this patient and the apparent failure of chemoprophylaxis with isoniazid are noted.
authors.affiliation: Department of Medicine, Walter Reed Army Medical Center, Washington, D.C. 20307-5001.
authors.forename: S C
authors.initials: SC
authors.lastname: Johnson
authors.forename: C P
authors.initials: CP
authors.lastname: Stamm
authors.forename: C B
authors.initials: CB
authors.lastname: Hicks
mesh_terms: D000038:Abscess / Q000150:complications* / Q000628:therapy; D000328:Adult; D003131:Combined Modality Therapy; D004322:Drainage; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use*; D008297:Male; D009135:Muscular Diseases / Q000150:complications* / Q000628:therapy; D014376:Tuberculosis / Q000150:complications* / Q000517:prevention & control / Q000628:therapy
chemical_list: D007538:Isoniazid