title: Trypanosoma cruzi histones. Further characterization and comparison with higher eukaryotes.
abstract: Histones extracted from T. cruzi chromatin were analyzed in three electrophoretic systems. Our results show that a basic protein with some properties similar to those of histone H1 from higher eukaryotes is present in T. cruzi. However this protein presents different electrophoretic mobilities than H1 histone from higher eukaryotes in all three electrophoretic systems tested. Considering the marked differences observed in the electrophoretic mobilities of T. cruzi histones as compared with those from higher eukaryotes, it is proposed that histones are conservative proteins primarily with regard to their function.
authors.affiliation: Departamento de Biología Celular y Genética, Facultad de Medicina, Universidad de Chile, Santiago.
authors.forename: G C
authors.initials: GC
authors.lastname: Toro
authors.forename: N
authors.initials: N
authors.lastname: Galanti
mesh_terms: D000818:Animals; D004591:Electrophoresis, Polyacrylamide Gel; D006657:Histones / Q000737:chemistry* / Q000302:isolation & purification; D008970:Molecular Weight; D011480:Protease Inhibitors / Q000494:pharmacology; D014349:Trypanosoma cruzi / Q000032:analysis*
chemical_list: D006657:Histones; D011480:Protease Inhibitors