title: [Melanoma of the skin: clinico-genetic studies].
abstract: As a result of clinico-genealogical analysis of data on 691 skin melanoma patients, a classification of skin melanoma was elaborated which reflected the etiologic heterogeneity of the disease. Inheritable and non-inheritable forms of skin melanoma were identified. The inheritable tumor group included familial disease (2%) and tumors developing against the background of hereditary diseases and syndromes (32.7%). The data obtained served as basis for the identification of families with high genetic predisposition to skin melanoma development and for the assessment of individual risk of the disease in patients' relatives.
authors.forename: T S
authors.initials: TS
authors.lastname: Sitnikova
authors.forename: R F
authors.initials: RF
authors.lastname: Gar'kavtseva
authors.forename: M D
authors.initials: MD
authors.lastname: Nefedov
authors.forename: L V
authors.initials: LV
authors.lastname: Demidov
mesh_terms: D000328:Adult; D004416:Dysplastic Nevus Syndrome / Q000235:genetics; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000145:classification / Q000235:genetics*; D008875:Middle Aged; D012878:Skin Neoplasms / Q000145:classification / Q000235:genetics*
vernacular_title: Melanoma kozhi: kliniko-geneticheskie issledovaniia.