title: [Sharp's syndrome].
abstract: The author presents the current concept of Sharp's syndrome and mixed connective tissue diseases, as well as the detailed composition, determined by modern immunological methods, of the U1-RNP antigen against which patients with this syndrome develop antibodies. A physiopathological concept of the syndrome is outlined.
authors.affiliation: Clinique de rhumatologie, Bichat, Université Paris VII.
authors.forename: M F
authors.initials: MF
authors.lastname: Kahn
mesh_terms: D000974:Antibodies, Antinuclear / Q000032:analysis; D006801:Humans; D008947:Mixed Connective Tissue Disease / Q000175:diagnosis / Q000276:immunology; D012261:Ribonucleoproteins / Q000276:immunology
chemical_list: D000974:Antibodies, Antinuclear; D012261:Ribonucleoproteins
vernacular_title: Syndrome de Sharp.