An advanced affinity membrane for covalent binding of amino ligands.
We report here an advanced, chemically active and yet hydrolytically stable microporous membrane which allows permanent covalent binding of amino ligands such as proteins. Rapid, single-step immobilizations produce a high density of immobilized ligands. Surface chemistry of the membrane is specifically designed to have extremely low nonspecific binding. Binding characteristics of the UltraBind membrane, various immobilization techniques and optimum immobilization conditions for diagnostic immunoassays are described.
Pemawansa
K P
KP
Heisler
M D
MD
Blackwell
S L
SL
Cymes
L
L
Mahalak
K L
KL
Kraus
M A
MA
D000588:Amines / Q000302:isolation & purification*; D000906:Antibodies / Q000302:isolation & purification; D001665:Binding Sites; D001709:Biotechnology; D003101:Collodion; D005069:Evaluation Studies as Topic; D008567:Membranes, Artificial; D009757:Nylons; D011506:Proteins / Q000302:isolation & purification
D000588:Amines; D000906:Antibodies; D008567:Membranes, Artificial; D009757:Nylons; D011506:Proteins; D003101:Collodion