title: Pulmonary complications after lung resection: the effect of continuous extrapleural intercostal nerve block.
abstract: To assess the efficacy of continuous extrapleural intercostal nerve block (CEINB) with 0.5% bupivacaine on postoperative pain, pulmonary function and pulmonary complications, a prospective, randomised, double blind controlled trial was conducted on comparable patients undergoing lung resections; n = 21 (control), n = 25 (bupivacaine). The bupivacaine group required less papaveretum in the first 24 h (P less than 0.01) and had lower pain scores over 5 postoperative days (P less than 0.01). Pulmonary function recovered earlier in the bupivacaine group. Pulmonary complications occurred in 1 patient with normal lung function and 12 patients with obstructive airways disease (COAD): FEV1/FVC less than 70%. There were no infusion-related complications. CEINB has been shown to be safe and effective in reducing postoperative pain and pulmonary complications. CEINB minimises the loss of lung function after thoracotomy and restores impaired pulmonary mechanics more rapidly.
authors.affiliation: Department of Thoracic Surgery, Bradford Royal Infirmary, UK.
authors.forename: R G
authors.initials: RG
authors.lastname: Berrisford
authors.forename: S S
authors.initials: SS
authors.lastname: Sabanathan
authors.forename: A J
authors.initials: AJ
authors.lastname: Mearns
authors.forename: P J
authors.initials: PJ
authors.lastname: Bickford-Smith
mesh_terms: D002045:Bupivacaine / Q000627:therapeutic use*; D006801:Humans; D015994:Incidence; D007367:Intercostal Nerves / Q000187:drug effects*; D009407:Nerve Block; D011183:Postoperative Complications / Q000188:drug therapy* / Q000453:epidemiology; D015995:Prevalence; D012307:Risk Factors; D013908:Thoracotomy / Q000009:adverse effects
chemical_list: D002045:Bupivacaine