title: [Pollinosis and bronchial asthma: pathogenesis, immunology, clinical aspects].
abstract: Rhinoconjunctivitis induced by pollen exposure and bronchial asthma are generally easily recognizable clinically. In asthma a number of differential diagnoses such as ciliary dyskinesia, cystic fibrosis and gastro-oesophageal reflux must be considered. The predominant symptoms are coughing and wheezing. Investigations into the complex nature of mediator release and IgE synthesis have established a predominantly inflammatory pattern of reactions largely responsible for induction and maintenance of bronchial hyperresponsiveness due to both acute and chronic processes. Future therapeutic consequences may be derived from anti-inflammatory strategies. This has already lead to reassessment and upgrading of use of corticosteroids in paediatric asthma.
authors.affiliation: Universitäts-Kinderklinik Wien.
authors.forename: M
authors.initials: M
authors.lastname: Götz
authors.forename: K
authors.initials: K
authors.lastname: Sanz
mesh_terms: D000485:Allergens / Q000276:immunology; D001249:Asthma / Q000175:diagnosis* / Q000276:immunology; D002648:Child; D002925:Ciliary Motility Disorders / Q000175:diagnosis; D003550:Cystic Fibrosis / Q000175:diagnosis; D003937:Diagnosis, Differential; D005764:Gastroesophageal Reflux / Q000175:diagnosis; D006801:Humans; D008407:Mast Cells / Q000276:immunology; D006255:Rhinitis, Allergic, Seasonal / Q000175:diagnosis* / Q000276:immunology
chemical_list: D000485:Allergens
vernacular_title: Pollinosis und Asthma bronchiale: Pathogenese, Immunologie, Klinik.