Antitumor activity of Borrelia burgdorferi cultures.
Cultures of B. burgdorferi, their supernatants as well as washed cells revealed in vitro a considerable antitumor activity against cells of Gardner lymphoma. Németh-Kellner lymphoma and LP-2 plasmacytoma. In in vivo tests an inhibition of tumor growth was evident, even if the treatment was started on day 4 after implantation of the tumor. The best results were obtained with the supernatants of the cultures.
Oravec
C
C
Cancer Research Institute, Slovak Academy of Sciences, Bratislava, Czechoslovakia.
Kmety
E
E
D000818:Animals; D015748:Borrelia burgdorferi Group / Q000276:immunology*; D002478:Cells, Cultured; D002857:Chromium / Q000378:metabolism; D066298:In Vitro Techniques; D008223:Lymphoma / Q000382:microbiology* / Q000628:therapy; D051379:Mice; D008807:Mice, Inbred BALB C; D008808:Mice, Inbred CBA; D010954:Plasmacytoma / Q000382:microbiology* / Q000628:therapy
D002857:Chromium