Metastatic malignant melanoma in pregnancy.
A 29 year old expectant mother was critically ill at 27 weeks gestation with disseminated metastatic malignant melanoma and was treated with dacarbazine. A dramatic remission was induced and at 38 weeks gestation she went into labour spontaneously and delivered a healthy infant. She relapsed and died eight weeks post partum. This is the first reported use of dacarbazine in pregnancy.
Harkin
K P
KP
Coombe Lying-in Hospital, Dolphins Barn, Dublin.
Drumm
J E
JE
O'Brien
P
P
Daly
A
A
D003606:Dacarbazine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008545:Melanoma / Q000188:drug therapy / Q000473:pathology; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000188:drug therapy / Q000473:pathology; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology
D003606:Dacarbazine