Immunohistochemical evidence for the presence of protein kinase C beta-subtype in rat motoneurons and myoneural junctions.
The localization of protein kinase C beta-subtype-like immunoreactivity (PKC-beta-LI) was studied in the spinal cord and in different striated muscles of rat. In the spinal cord, large motoneurons in the ventral horn were PKC-beta-immunoreactive (IR). Strong immunoreactivity to PKC-beta was found in large nerve bundles between muscles, and in smaller nerves among muscle fibers. Myoneural junctions, which showed weaker immunoreactivity to PKC-beta, were also demonstrated in all muscles studied; the external ocular muscles, the diaphragma and the triceps surae muscle. Muscle cells were not labelled.
Hietanen
M
M
Department of Biomedical Sciences, University of Tampere, Finland.
Koistinaho
J
J
Rechardt
L
L
Roivainen
R
R
Pelto-Huikko
M
M
D000818:Animals; D003964:Diaphragm / Q000294:innervation; D007150:Immunohistochemistry; D008297:Male; D009046:Motor Neurons / Q000166:cytology / Q000201:enzymology*; D009469:Neuromuscular Junction / Q000201:enzymology* / Q000648:ultrastructure; D011493:Protein Kinase C / Q000378:metabolism*; D051381:Rats; D011919:Rats, Inbred Strains; D013116:Spinal Cord / Q000166:cytology / Q000201:enzymology*
D011493:Protein Kinase C