title: Effect of coumarin on glucose uptake by anaerobic rumen fungi in the presence and absence of Methanobrevibacter smithii.
abstract: The effect of coumarin (1,2 benzopyrone) on glucose utilisation by the anaerobic rumen fungi Neocallimastix frontalis and N. patriciarum has been compared with the effect of p-coumaric acid. Both compounds largely inhibited glucose utilisation by N. patriciarum strain Cx when present in the medium at a concentration of 2.5 mM, and had a similar effect on N. frontalis strain RE1 at 5 mM. Although in earlier studies co-culturing rumen fungi with Methanobrevibacter smithii enhanced resistance to ionophores, no comparable protective effect of M. smithii was found in the present study.
authors.affiliation: Biology Dept., Hacetteppe University, Ankara, Turkey.
authors.forename: E
authors.initials: E
authors.lastname: Cansunar
authors.forename: A J
authors.initials: AJ
authors.lastname: Richardson
authors.forename: G
authors.initials: G
authors.lastname: Wallace
authors.forename: C S
authors.initials: CS
authors.lastname: Stewart
mesh_terms: D000818:Animals; D003374:Coumarins / Q000494:pharmacology*; D019605:Euryarchaeota / Q000378:metabolism; D005658:Fungi / Q000187:drug effects* / Q000254:growth & development; D005947:Glucose / Q000378:metabolism*; D012417:Rumen / Q000382:microbiology
chemical_list: D003374:Coumarins; C030123:coumarin; D005947:Glucose