[The effect of tuftsin on various aspects of metabolism in the sensorimotor system of the animal brain].
Rates of synthesis and degradation of monoamines, acetyl choline and protein were distinctly altered in cortex-subcortex structures of the brain locomotory system after a single administration of tetrapeptide tuftsin Thr-Lys-Pro-Arg during the period 15-30 min of its pronounced effect on the animal motor activity. Correlation between the functional and morphological alterations in cellular and subcellular brain structures, caused by the peptide administration, is discussed.
Gershteĭn
L M
LM
Dovedova
E L
EL
Kamysheva
A S
AS
Sergutina
A V
AV
Chebotareva
T L
TL
D000110:Acetylcholinesterase / Q000378:metabolism; D000626:Aminopeptidases / Q000378:metabolism; D000818:Animals; D006651:Histocytochemistry; D008297:Male; D008995:Monoamine Oxidase / Q000378:metabolism; D011817:Rabbits; D051381:Rats; D011919:Rats, Inbred Strains; D013003:Somatosensory Cortex / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D014405:Tuftsin / Q000494:pharmacology*
D008995:Monoamine Oxidase; D000110:Acetylcholinesterase; D000626:Aminopeptidases; D014405:Tuftsin
Vliianie taftsina na nekotorye storony obmena v dvigatel'noĭ sisteme mozga zhivotnykh.