title: [Ambulatory carboplatin monotherapy in advanced seminoma].
abstract: Six patients with advanced seminoma (stage IIc) received single-agent carboplatin therapy. The drug was administered to outpatients without prior hyperhydration. All five patients who completed the regimen of three to four cycles achieved complete remission, which was confirmed histologically in four patients by retroperitoneal lymph node dissection. No severe side-effects were observed. Single-agent carboplatin therapy is a highly efficient regimen with very little toxicity. This treatment seems to be the therapy of choice in patients with advanced seminoma.
authors.affiliation: Urologische Klinik, Universitätsklinikum Steglitz, Freie Universität Berlin.
authors.forename: K P
authors.initials: KP
authors.lastname: Dieckmann
authors.forename: G
authors.initials: G
authors.lastname: Bornhoeft
authors.forename: H
authors.initials: H
authors.lastname: Huland
mesh_terms: D000293:Adolescent; D000328:Adult; D016190:Carboplatin / Q000009:adverse effects / Q000627:therapeutic use*; D004407:Dysgerminoma / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012186:Retroperitoneal Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D013736:Testicular Neoplasms / Q000188:drug therapy* / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D016190:Carboplatin
vernacular_title: Ambulante Carboplatin-Monotherapie beim forgeschrittenen Seminom.