title: [Comparative histomorphometric study of acromegalic spongy bone. Formative static parameters].
abstract: The authors used static histomorphometric parameters obtained by processing of bioptic bone specimens for comparison of normal and acromegalic spongious bone. Parameters of the bone volume (V), osteoid volume (Vos), the extent of osteoid bone surfaces (Sf) in the two groups do not differ statistically. The two groups do not differ as to age distribution. The width of bone trabeculae is greater in acromegalic bone; the difference as compared with normal bone specimens is statistically significant (p less than 0.05). The authors conclude that STH in acromegalics subjects does not stimulate osteoid production in trabecular bone to shift the balance between bone resorption and formation significantly in favour of formation. Only restructuring of trabecular acromegalic bone occurs.
authors.affiliation: III. interní katedra 1. lékarské fakulty Univerzity Karlovy, Praha.
authors.forename: J
authors.initials: J
authors.lastname: Zák
authors.forename: C
authors.initials: C
authors.lastname: Povýsil
authors.forename: V
authors.initials: V
authors.lastname: Pacovský
authors.forename: J
authors.initials: J
authors.lastname: Marek
mesh_terms: D000172:Acromegaly / Q000473:pathology*; D001842:Bone and Bones / Q000473:pathology*; D006801:Humans
vernacular_title: Srovnávací histomorfometrická studie akromegalické spongiózní kosti. Formativní statické parametry.