Rash after treatment with anistreplase.
A palpable purpura developed on the legs and lower abdomen of a woman of 54 five days after she was treated with anistreplase anisoylated plasminogen streptokinase activator complex (APSAC) for an acute myocardial infarction. Histological examination of a skin biopsy specimen taken 6 days after treatment showed leucocytoclastic vasculitis. The rash resolved within two weeks and there were no other complications.
Burrows
N
N
Department of Dermatology, Ealing Hospital, Southall, Middlesex.
Jones
R R
RR
D016255:Anistreplase / Q000009:adverse effects*; D005260:Female; D006801:Humans; D011695:IgA Vasculitis / Q000139:chemically induced* / Q000473:pathology; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy; D012867:Skin / Q000473:pathology; D015912:Thrombolytic Therapy / Q000009:adverse effects*
D016255:Anistreplase