Deletion of chromosome 4: 46,XY, del(4) (q31.3) after gamete intrafallopian transfer and in vitro fertilization-embryo transfer.
It seems that assisted reproduction technology does not increase the rate of chromosome abnormalities, and up to now, a few cases have been reported. The case we describe here is the first one of monosomy 4q31 in a full-term liveborn after a combined GIFT-IVF procedure. Once more, this case raises the question of whether pregnancies resulting from IVF should be monitored for chromosome abnormalities or not.
Tejada
M I
MI
Department of Obstetrics and Gynecology, Hospital de Cruces, Baracaldo, Vizcaya, Spain.
Mendoza
R
R
Carbonero
K
K
Lizarraga
M A
MA
Escudero
F
F
Benito
J A
JA
D000328:Adult; D002872:Chromosome Deletion; D002894:Chromosomes, Human, Pair 4; D000013:Congenital Abnormalities / Q000235:genetics; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D015181:Gamete Intrafallopian Transfer; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D012730:Sex Chromosomes