title: Increased endothelin concentration in CSF from patients with subarachnoid hemorrhage.
abstract: A considerable quantity of endothelin-like immunoreactivity was demonstrated as present in the CSF of patients with subarachnoid hemorrhage. The endothelin levels in the CSF raised from 0.4 +/- 0.2 (Mean +/- SD) pmol/L at Day 0-1 to 2.2 +/- 0.6 pmol/L at Day 6 and the levels decreased gradually. The result suggest that endothelin may contribute the generation of vasospasm often observed in subarachnoid hemorrhage.
authors.affiliation: Department of Endocrinology, Dokkyo University School of Medicine, Mibu, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Suzuki
authors.forename: S
authors.initials: S
authors.lastname: Sato
authors.forename: Y
authors.initials: Y
authors.lastname: Suzuki
authors.forename: K
authors.initials: K
authors.lastname: Takekoshi
authors.forename: N
authors.initials: N
authors.lastname: Ishihara
authors.forename: S
authors.initials: S
authors.lastname: Shimoda
mesh_terms: D016232:Endothelins / Q000134:cerebrospinal fluid*; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000134:cerebrospinal fluid*; D008297:Male; D008875:Middle Aged; D011863:Radioimmunoassay; D013345:Subarachnoid Hemorrhage / Q000134:cerebrospinal fluid*
chemical_list: D016232:Endothelins