Cyclophosphamide-induced hemorrhagic pyelitis and ureteritis associated with cystitis in marrow transplantation.
A 29-year-old woman suffered fatal hemorrhagic pyelitis, ureteritis and cystitis after receiving 4,800 mg./m.2 cyclophosphamide in preparation for marrow transplantation despite intravenous hydration and a Foley catheter. Cyclophosphamide-induced urothelial damage is not limited to the bladder and upper tract monitoring also is necessary.
Efros
M
M
Department of Urology, New York Medical College, Valhalla 10595.
Ahmed
T
T
Choudhury
M
M
D000328:Adult; D016026:Bone Marrow Transplantation; D003520:Cyclophosphamide / Q000009:adverse effects* / Q000627:therapeutic use; D003556:Cystitis / Q000139:chemically induced*; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced*; D006689:Hodgkin Disease / Q000601:surgery; D006801:Humans; D011702:Pyelitis / Q000139:chemically induced*; D014515:Ureteral Diseases / Q000139:chemically induced*
D003520:Cyclophosphamide