Synthesis and pharmacological studies of some (1,4)-naphthoquinono[3,2-c]-1H-pyrazoles, 2-substituted amino-1,4-naphthoquinones, and related compounds.
Series of (1,4)-Naphthoquinono(3,2-c)-1H-pyrazoles and 2-substituted amino-1,4-naphthoquinones have been synthesised and studied for their possible anticancer activity (animal tumours, Walker 256 carcinosarcoma), Influenza RNA transcriptase activity, antibiotic activity (C. neoformans, T. mentagraphytes, M. canis, A. niger, and C. albicans).
Tandon
V K
VK
Department of Chemistry, Lucknow University, India.
Vaish
M
M
Khanna
J M
JM
Anand
N
N
D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D001419:Bacteria / Q000187:drug effects; D002478:Cells, Cultured; D055598:Chemical Phenomena; D002621:Chemistry; D005658:Fungi / Q000187:drug effects; D009285:Naphthoquinones / Q000138:chemical synthesis* / Q000494:pharmacology; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000494:pharmacology
D000970:Antineoplastic Agents; D009285:Naphthoquinones; D011720:Pyrazoles