Studies on the ecological impact of antibiotics.
The presence of an antibiotic in the intestinal tract as a result of oral administration or intestinal excretion can have a pronounced impact of the microflora. Studies of the effect on the intestinal microflora and faecal excretion should therefore be carried out in volunteers and patients when new antibacterial agents are evaluated. These two analyses should be combined in the evaluation.
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Department of Microbiology, Huddinge University Hospital, Karolinska Institute, Stockholm, Sweden.
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D004341:Drug Evaluation; D006801:Humans; D007408:Intestinal Absorption; D007413:Intestinal Mucosa / Q000187:drug effects / Q000382:microbiology*; D015163:Superinfection / Q000150:complications
D000900:Anti-Bacterial Agents