title: Subungual melanoma of the hand.
abstract: Thirteen patients with subungual melanoma on the fingers had a mean delay before diagnosis of 1.2 years. Four patients presented with local recurrence after inadequate initial treatment and two presented with systemic metastases. Mean primary subungual melanoma thickness was 6.1 mm. and nine patients had Clark level IV or V disease. All patients underwent digital amputation. Two of seven patients who had localised disease initially are alive at 29 and 44 months. One of four patients who had locally recurrent melanoma is alive at 36 months. Both patients with systemic disease at presentation died. Advanced disease and delayed presentation contributed to the poor prognosis of subungual melanoma in our patients.
authors.affiliation: University of Cape Town, South Africa.
authors.forename: D A
authors.initials: DA
authors.lastname: Hudson
authors.forename: J E
authors.initials: JE
authors.lastname: Krige
authors.forename: R M
authors.initials: RM
authors.lastname: Strover
authors.forename: H S
authors.initials: HS
authors.lastname: King
mesh_terms: D000328:Adult; D000368:Aged; D000671:Amputation, Surgical; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008545:Melanoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D009260:Nail Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D009262:Nails / Q000473:pathology; D011379:Prognosis; D012008:Recurrence