title: [Differential prevention of recurrence of thrombosis during pregnancy].
abstract: Pregnancy in patients with a history of thrombotic complications puts them at a great risk of thrombosis and obstetric complications (hypoxia, intrauterine hypotrophy, bleedings). Functional strain of the hemostasis system occurs at the onset of pregnancy in women with a history of thrombotic complications without clinical symptoms of thrombosis. The incidence of disseminated intravascular coagulation with activation of both pro-coagulation and platelet-mediated hemostasis is 33% and that with activation of only platelet-mediated hemostasis is 64%. Differential use of antithrombotic drugs prevents thrombosis recurrence in 98% of patients.
authors.forename: A D
authors.initials: AD
authors.lastname: Makatsariia
authors.forename: I G
authors.initials: IG
authors.lastname: Prosviriakova
authors.forename: A L
authors.initials: AL
authors.lastname: Mishchenko
authors.forename: L A
authors.initials: LA
authors.lastname: Kazakova
mesh_terms: D000328:Adult; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000209:etiology / Q000517:prevention & control*; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006487:Hemostasis / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood / Q000209:etiology / Q000517:prevention & control*; D011250:Pregnancy Complications, Hematologic / Q000097:blood / Q000209:etiology / Q000517:prevention & control*; D012008:Recurrence; D013923:Thromboembolism / Q000097:blood / Q000209:etiology / Q000517:prevention & control*
chemical_list: D005343:Fibrinolytic Agents
vernacular_title: Differentsirovannaia profilaktika retrombozov vo vremia gestatsionnogo protsessa.