title: Cocaine-induced hepatonephrotoxicity: a case report.
abstract: Hepatotoxicity due to cocaine has been well described in animal models. There are few reports on cocaine-induced hepatic injury in humans; however, its link to rhabdomyolysis and renal failure is better known. We report a case of reversible acute hepatonephrotoxicity associated with recreational cocaine use. The proposed mechanisms responsible for its hepatic and renal toxicity are reviewed.
authors.affiliation: Division of Gastroenterology, Henry Ford Hospital, Detroit, MI 48202.
authors.forename: G P
authors.initials: GP
authors.lastname: Gubbins
authors.forename: R M
authors.initials: RM
authors.lastname: Schiffman
authors.forename: R S
authors.initials: RS
authors.lastname: Alapati
authors.forename: S K
authors.initials: SK
authors.lastname: Batra
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced*; D000328:Adult; D056486:Chemical and Drug Induced Liver Injury; D003042:Cocaine / Q000009:adverse effects*; D005260:Female; D006801:Humans
chemical_list: D003042:Cocaine