title: [Chronochemotherapy of neoplasms].
abstract: The problems of chronobiology in chemotherapy are discussed in connection with experimental and clinical experience. Special attention is payed to selected from most commonly applied cytostatics cis-platinum and doxorubicin, their toxicity in different hours of the day and efficacy in treatment of malignant neoplasms in human.
authors.affiliation: Pracowni Radiobiologii Klinicznej Kliniki Radioterapii Centrum Onkologii, Instytutu im. Marii Skłodowskiej-Curie Oddział w Krakowie.
authors.forename: B
authors.initials: B
authors.lastname: Lackowska
mesh_terms: D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use* / Q000633:toxicity; D002909:Chronobiology Phenomena; D002940:Circadian Rhythm; D002945:Cisplatin / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use* / Q000633:toxicity; D004317:Doxorubicin / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use* / Q000633:toxicity; D004361:Drug Tolerance; D006801:Humans; D051379:Mice; D009369:Neoplasms / Q000188:drug therapy*; D009374:Neoplasms, Experimental / Q000188:drug therapy*; D051381:Rats
chemical_list: D004317:Doxorubicin; D002945:Cisplatin
vernacular_title: Chronochemioterapia nowotworów.