title: Management and outcome of gestational diabetes in Alexandra Hospital, Singapore.
abstract: We analysed 216 patients with gestational diabetes over a 3 year period. These patients were managed by a diabetic team under a standardised protocol. Forty percent of these patients required insulin therapy. The incidence of pregnancy hypertension was 14.4%, macrosomia 8.8% and major congenital malformation 3.7%. The Caesarean Section rate was 34% and the overall Perinatal Mortality Rate was 1.9%. However, neonatal morbidity rate remained high--44% of infants have had one neonatal complication and 17.6% had 2 or more complications. Pregnancy outcome was further analysed among patients with different degrees of glucose intolerance at diagnosis. We noted that both macrosomic rate, neonatal morbidity rate, as well as proportion of patients requiring insulin were higher in the group with a higher degree of glucose intolerance. There was, however, no difference in incidence of hypertension or hydramnios in the different subgroups.
authors.affiliation: Department of Maternal-Fetal Medicine, Kandang Kerbau Hospital, Singapore.
authors.forename: C S
authors.initials: CS
authors.lastname: Tee
authors.forename: K W
authors.initials: KW
authors.lastname: Wang
authors.forename: C K
authors.initials: CK
authors.lastname: Tho
authors.forename: T L
authors.initials: TL
authors.lastname: Heng
authors.forename: C
authors.initials: C
authors.lastname: Rajasoorya
authors.forename: D
authors.initials: D
authors.lastname: Vengadasalam
authors.forename: Y T
authors.initials: YT
authors.lastname: Tan
mesh_terms: D003920:Diabetes Mellitus / Q000178:diet therapy / Q000188:drug therapy; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D006973:Hypertension; D007328:Insulin / Q000008:administration & dosage / Q000627:therapeutic use; D011247:Pregnancy; D011256:Pregnancy Outcome; D011254:Pregnancy in Diabetics / Q000178:diet therapy / Q000188:drug therapy; D012846:Singapore
chemical_list: D007328:Insulin