[Bronchoconstrictive and bronchodilating effects of acetylsalicylic acid in patients with bronchial asthma].
An aspirin test has been performed in 100 asthma patients. The response of the bronchi appeared contradictory: aspirin asthma on the one hand, and bronchodilatation on the other occurred in 31 and 28 patients, respectively; 41 patients appeared nonresponders. Maximum effect of the drug was noted in the small bronchi. Desensitization to aspirin and hemosorption reduced asthma patients sensitivity to nonsteroid antiinflammatory drugs.
Treskunov
V K
VK
Didkovskiĭ
N A
NA
Zakharzhevskaia
T V
TV
Evseev
N G
NG
D000293:Adolescent; D000328:Adult; D000368:Aged; D001241:Aspirin / Q000009:adverse effects* / Q000627:therapeutic use; D001249:Asthma / Q000188:drug therapy*; D001980:Bronchi / Q000187:drug effects* / Q000276:immunology; D001986:Bronchial Spasm / Q000139:chemically induced*; D016085:Bronchoconstrictor Agents / Q000627:therapeutic use*; D001993:Bronchodilator Agents; D004342:Drug Hypersensitivity / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged
D016085:Bronchoconstrictor Agents; D001993:Bronchodilator Agents; D001241:Aspirin
Bronkhokonstriktornoe i bronkhodilatiruiushchee deĭstvie atsetil- salitsilovoĭ kisloty u bol'nykh bronkhial'noĭ astmoĭ.