title: Kinetics of the trypsinogen activation by enterokinase and trypsin.
abstract: A global kinetic analysis of the mechanisms of the trypsinogen activation by enterokinase and trypsin is presented. The kinetic equations of both the transient-phase and the steady-state of these mechanisms are presented. In addition, we here derive the corresponding kinetic equations for the case in which the condition of rapid equilibrium prevails and we propose a kinetic data analysis. The significance of this approach to the treatment of other zymogen activation processes is discussed.
authors.affiliation: Biochemisches Institut, Christian Albrechts Universität zu Kiel, West Germany.
authors.forename: R
authors.initials: R
authors.lastname: Varón
authors.forename: B H
authors.initials: BH
authors.lastname: Havsteen
authors.forename: A
authors.initials: A
authors.lastname: Vázquez
authors.forename: M
authors.initials: M
authors.lastname: García
authors.forename: E
authors.initials: E
authors.lastname: Valero
authors.forename: F
authors.initials: F
authors.lastname: García Cánovas
mesh_terms: D000818:Animals; D004765:Enteropeptidase / Q000378:metabolism*; D004789:Enzyme Activation; D007700:Kinetics; D008954:Models, Biological; D013223:Statistics as Topic; D014357:Trypsin / Q000378:metabolism*; D014362:Trypsinogen / Q000378:metabolism*
chemical_list: D014362:Trypsinogen; D014357:Trypsin; D004765:Enteropeptidase