title: [A bulky mass non-Hodgkin's lymphoma with dysuria in the rectovesical space].
abstract: A case of non-Hodgkin's lymphoma is reported. A 71-year-old man presented with complaint of dysuria and urinary frequency. Rectal examination and CT scan revealed a bulky mass in the rectovesical space. Transperineal needle biopsy of the tumor revealed non-Hodgkin's lymphoma, large cell type, diffuse. The patient received combination chemotherapy of adriamycin, cyclophosphamide, vincristine, prednisolone and pepleomycin. After two days the tumor was marvelously reduced in size, and partial response (PR) by CT was achieved after two months. PR was sustained for two months with cyclophosphamide, vincristine and prednisolone. However, the tumor progressed gradually, and he died five months after the first treatment and two additional courses of chemotherapy. Autopsy showed a 1,700 g bulky mass in the rectovesical space. The mass was covered with peritoneum and had a fistula from rectum to central necrosis of the tumor. Nine cases of the non-Hodgkin's lymphoma with complaint of dysuria have been reported in Japan before our case, which seemed to arise from the submucosal tissue of anterior rectal wall, prostate or lymphatic tissue of rectovesical space.
authors.affiliation: Department of Urology, Fujisawa City Hospital.
authors.forename: A
authors.initials: A
authors.lastname: Tosaka
authors.forename: A
authors.initials: A
authors.lastname: Yamazaki
authors.forename: M
authors.initials: M
authors.lastname: Hirokawa
authors.forename: K
authors.initials: K
authors.lastname: Matsushita
authors.forename: S
authors.initials: S
authors.lastname: Asakura
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D009378:Neoplasms, Multiple Primary; D011241:Prednisone / Q000008:administration & dosage; D012004:Rectal Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D014555:Urination Disorders / Q000209:etiology*; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone