title: Membranous nephropathy associated with giant lymph node hyperplasia. A case report with histological and ultrastructural studies.
abstract: A young woman presented with nephrotic syndrome due to membranous nephropathy and a localized form of giant lymph node hyperplasia (Castleman's disease) occurring as a large intra-abdominal mass. Five months after surgical removal of the mass, only mild proteinuria persisted. Twenty months later a second kidney biopsy showed a near-normal morphology. Six years later the patient was free of symptoms and had normal urinalysis. Reviewing the pertinent literature, it seems to be the first case of a biopsy-proven cure of membranous nephropathy in a patient with membranous nephropathy and Castleman's disease.
authors.affiliation: Servizio di Nefrologia e Dialisi, Ospedale San Giacomo, Roma, Italia.
authors.forename: G
authors.initials: G
authors.lastname: Ruggieri
authors.forename: P
authors.initials: P
authors.lastname: Barsotti
authors.forename: G
authors.initials: G
authors.lastname: Coppola
authors.forename: C
authors.initials: C
authors.lastname: Spinelli
authors.forename: A
authors.initials: A
authors.lastname: Balducci
authors.forename: F R
authors.initials: FR
authors.lastname: Ventola
authors.forename: G
authors.initials: G
authors.lastname: d'Adamo
authors.forename: M V
authors.initials: MV
authors.lastname: Tata
authors.forename: V
authors.initials: V
authors.lastname: Marinozzi
mesh_terms: D000293:Adolescent; D001706:Biopsy; D005871:Castleman Disease / Q000150:complications* / Q000473:pathology / Q000601:surgery; D005260:Female; D015433:Glomerulonephritis, Membranous / Q000150:complications* / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology*; D008854:Microscopy, Electron