[Gastroesophageal reflux and respiratory manifestations: diagnostic approach, therapeutic indications and results].
The authors report a study of 140 patients presenting with a non-allergic respiratory tract disease (121 cases of asthma--19 cases of spasmodic cough). Gastro-oesophageal reflux was detected by 24-hour pHmetry in 86 of these patients. In 34 of them (i.e. 40% of cases), the gastro-oesophageal reflux appeared to be responsible for the initial respiratory tract symptoms. These 34 patients were submitted to a therapeutic trial of high dose anti-H2 therapy for at least two months. Only those patients in whom a marked improvement or even complete resolution of the respiratory tracts symptoms was observed underwent anti-reflux surgery. Out of the 13 patients undergoing surgery, there were two failures and 11 good results after a follow-up of more than 18 months.
Giudicelli
R
R
Service de Chirurgie Thoracique et des Maladies de l'Oesophage, Hôpital Sainte-Marguerite, Marseille.
Dupin
B
B
Surpas
P
P
Badier
M
M
Charpin
D
D
Lapicque
J C
JC
Fuentes
P
P
Reboud
E
E
D001249:Asthma / Q000209:etiology*; D003371:Cough / Q000209:etiology*; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
Reflux gastro-oesophagien et manifestations respiratoires: attitude diagnostique, indications thérapeutiques et résultats.