title: Ro 40-7592, a novel, very potent, and orally active inhibitor of catechol-O-methyltransferase: a pharmacological study in rats.
authors.affiliation: Pharmaceutical Research Department, F. Hoffmann-La Roche Ltd, Basle, Switzerland.
authors.forename: G
authors.initials: G
authors.lastname: Zürcher
authors.forename: H H
authors.initials: HH
authors.lastname: Keller
authors.forename: R
authors.initials: R
authors.lastname: Kettler
authors.forename: J
authors.initials: J
authors.lastname: Borgulya
authors.forename: E P
authors.initials: EP
authors.lastname: Bonetti
authors.forename: R
authors.initials: R
authors.lastname: Eigenmann
authors.forename: M
authors.initials: M
authors.lastname: Da Prada
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001577:Benzophenones / Q000494:pharmacology*; D065098:Catechol O-Methyltransferase Inhibitors; D046508:Culture Techniques; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D009596:Nitrophenols; D051381:Rats; D013329:Structure-Activity Relationship; D000077867:Tolcapone
chemical_list: D001577:Benzophenones; D065098:Catechol O-Methyltransferase Inhibitors; D009596:Nitrophenols; D000077867:Tolcapone