[Experimental studies for photodynamic therapy of malignant tumors of the mouth cavity, larynx and pharynx with the photosensitizer methylene blue].
Squamous-cell carcinomas of the upper aerodigestive tract can be destroyed in vitro through photosensitization with Methylene blue and subsequent radiation with red laser light. It is impossible to obtain the same results with sensitization or light radiation alone. The paper discusses the conditions under which this procedure might develop into a truly selective photodynamic therapy method.
Kleemann
D
D
Hals-Nasen-Ohren-Klinik, Bereiches Medizin der Wilhelm-Pieck-Universität Rostock.
D002294:Carcinoma, Squamous Cell / Q000188:drug therapy*; D002470:Cell Survival / Q000187:drug effects*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000188:drug therapy*; D053685:Laser Therapy; D008751:Methylene Blue / Q000627:therapeutic use*; D009062:Mouth Neoplasms / Q000188:drug therapy*; D010610:Pharyngeal Neoplasms / Q000188:drug therapy*; D010778:Photochemotherapy / Q000295:instrumentation*; D014407:Tumor Cells, Cultured / Q000187:drug effects*
D008751:Methylene Blue
Experimentelle Untersuchungen zur photodynamischen Therapie von malignen Tumoren der Mundhöhle, des Larynx und Pharynx mit dem Photosensibilisator Methylenblau.