title: [A pharmacological analysis of the cholinergic system in animals with alloxan diabetes].
abstract: In the animal experiment the sensitivity to acetylcholine was shown to increase in alloxan-induced hypoinsulinemia. The blockade of M-cholinoreactive structure produced by administration of amizil caused a deterioration of the condition of the animals with alloxan-induced diabetes. The increased sensitivity to acetylcholine was accompanied by changes in the activity of acetylcholine esterase in the hypothalamus nuclei.
authors.forename: M D
authors.initials: MD
authors.lastname: Khegaĭ
mesh_terms: D000109:Acetylcholine / Q000097:blood / Q000494:pharmacology; D000110:Acetylcholinesterase / Q000378:metabolism; D000818:Animals; D001535:Benactyzine / Q000494:pharmacology; D001786:Blood Glucose / Q000032:analysis; D003921:Diabetes Mellitus, Experimental / Q000378:metabolism*; D005260:Female; D007328:Insulin / Q000494:pharmacology; D008297:Male; D011817:Rabbits; D051381:Rats; D011950:Receptors, Cholinergic / Q000187:drug effects* / Q000378:metabolism
chemical_list: D001786:Blood Glucose; D007328:Insulin; D011950:Receptors, Cholinergic; D001535:Benactyzine; D000110:Acetylcholinesterase; D000109:Acetylcholine
vernacular_title: Farmakologicheskiĭ analiz kholinergicheskoĭ sistemy u zhivotnykh s alloksanovym diabetom.