Mineralization of polyurethane membranes in the total artificial heart (TAH): a retrospective study from long-term animal experiments.
The degree of mineralization of TAH membranes in animals is directly related to the survival time of animals with a TAH. Large differences in mineralization of the membranes among individual animals have been observed. These differences can be explained by the simultaneous presence of infection on biomaterials (polyurethane) as well as by different levels of natural inhibitors of mineralization. No positive influence of applying sodium warfarin for the inhibition of the mineralization was observed.
Dostál
M
M
Department of Pathophysiology, Faculty of Medicine, Masaryk University, Brno-CSFR.
Vasků
J
J
Vasků
J
J
Sotolová
O
O
Vasků
A
A
Dolezel
S
S
Hartmannová
B
B
D000818:Animals; D001672:Biocompatible Materials; D002130:Calcium Phosphates; D002417:Cattle; D006041:Goats; D006354:Heart, Artificial; D008567:Membranes, Artificial; D008855:Microscopy, Electron, Scanning; D011140:Polyurethanes
D001672:Biocompatible Materials; D002130:Calcium Phosphates; D008567:Membranes, Artificial; D011140:Polyurethanes; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; C020243:calcium phosphate; C485829:calcium phosphate, dibasic, anhydrous