title: Fructosamine compared with a glucose load as a screening test for gestational diabetes.
abstract: Five hundred seven women were screened for gestational diabetes between 20-36 weeks' gestation. All received a 100-g glucose (polycose) load at 28 weeks with measurement of plasma glucose 1 hour later. Fructosamine levels were measured at 4-week intervals from 20-36 weeks. At 36 weeks, a full 100-g 3-hour glucose tolerance test was performed on all subjects. Eighteen women were diagnosed as having gestational diabetes. The glucose load had a sensitivity of 81% in detection of gestational diabetes, compared with 50% for fructosamine at 36 weeks. Fructosamine is not useful as a screening test for gestational diabetes as currently defined.
authors.affiliation: Department of Obstetrics, National Women's Hospital, Auckland, New Zealand.
authors.forename: A B
authors.initials: AB
authors.lastname: Roberts
authors.forename: J R
authors.initials: JR
authors.lastname: Baker
authors.forename: P
authors.initials: P
authors.lastname: Metcalf
authors.forename: C
authors.initials: C
authors.lastname: Mullard
mesh_terms: D003920:Diabetes Mellitus / Q000175:diagnosis* / Q000517:prevention & control; D005260:Female; D019270:Fructosamine; D005951:Glucose Tolerance Test; D006595:Hexosamines; D006801:Humans; D008403:Mass Screening; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000175:diagnosis* / Q000517:prevention & control; D012680:Sensitivity and Specificity
chemical_list: D006595:Hexosamines; D019270:Fructosamine