Plasma concentrations of bupivacaine after stellate ganglion block using two volumes of 0.25% bupivacaine plain solution.
Plasma concentrations of bupivacaine were measured in patients after stellate ganglion block using either 10 or 20 ml of 0.25% plain solution. The mean peak concentrations were greater in the larger volume group, but this was not statistically significant. From 30 min after injection, there was a significantly greater plasma concentration in the larger volume group. The concentrations approached the limit of detection in the smaller volume group at 2 h after block.
Hardy
P A
PA
Pain Clinic, Whiston Hospital, Prescot, Merseyside.
Williams
N E
NE
D000772:Anesthesia, Local; D001340:Autonomic Nerve Block; D002045:Bupivacaine / Q000008:administration & dosage / Q000097:blood*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007267:Injections; D011446:Prospective Studies; D013233:Stellate Ganglion; D013997:Time Factors
D002045:Bupivacaine