A trial that failed, and the reasons why: comparing the Minnesota model with outpatient treatment and non-treatment for alcohol disorders.
A randomised clinical trial was conducted in order to compare treatment results between Minnesota model treatment for alcohol abuse and outpatient treatment. The trial had to be discontinued due to problems in recruitment of subjects and a high rate of attrition among subjects allocated to Minnesota model treatment. In this paper the problems encountered during the trial are discussed. Different methods of recruitment of subjects to a randomised trial are compared.
Andréasson
S
S
Department of medicine, Karolinska Institute, Huddinge University Hospital, Sweden.
Parmander
M
M
Allebeck
P
P
D000437:Alcoholism / Q000523:psychology / Q000628:therapy*; D000553:Ambulatory Care; D005500:Follow-Up Studies; D006760:Hospitalization; D006801:Humans; D008910:Minnesota; D008960:Models, Psychological; D010865:Pilot Projects; D011897:Random Allocation; D012107:Research Design; D011795:Surveys and Questionnaires; D013548:Sweden