title: [MRI of acute myocardial infarction with injection of Gd-DOTA (15 patients)].
abstract: We studied 15 patients 4 to 8 days after myocardial infarction by using ECG gated MR before and after administration of 0.2 mmol/kg Gd-DOTA. The diagnosis in each patient was confirmed by electrocardiographic criteria, elevated levels of fractionated creatine kinase (CK) isoenzyme, thallium scintigraphy, ventriculography and coronarography. T1-weighted, spin-echo images, were obtained before and immediately after injection of Gd-DOTA and were repeated 15 min later. The site of infarction was visualised in 10 patients as an area of high signal intensity after the injection of Gd-DOTA. Contrast between normal and infarcted myocardium was greatest 15 min after injection. Three patients were excluded because of failure to acquire adequate MR studies. In 2 other patients, the infarct were not detected. Before injection of Gd-DOTA, only 2 infarcts were detected. These results suggest that Gd-DOTA can improve MR visualisation and detection of acute myocardial infarction.
authors.affiliation: Service de Radiologie, Hôpital Erasme, Bruxelles, Belgique.
authors.forename: B
authors.initials: B
authors.lastname: Richoz
authors.forename: C
authors.initials: C
authors.lastname: Delcour
authors.forename: P
authors.initials: P
authors.lastname: Depelchin
authors.forename: A
authors.initials: A
authors.lastname: Lenaers
authors.forename: C
authors.initials: C
authors.lastname: Jacquemin
authors.forename: P
authors.initials: P
authors.lastname: Gusella
authors.forename: J
authors.initials: J
authors.lastname: Struyven
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006571:Heterocyclic Compounds / Q000008:administration & dosage*; D006801:Humans; D007275:Injections, Intravenous; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000473:pathology*; D009206:Myocardium / Q000473:pathology*; D009942:Organometallic Compounds / Q000008:administration & dosage*
chemical_list: D006571:Heterocyclic Compounds; D009942:Organometallic Compounds; C050823:gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate
vernacular_title: IRM de l'infarctus myocardique aigu avec injection de Gd-DOTA (quinze patients).