Prevalence & clinical associations of anticardiolipin antibodies in patients with systemic lupus erythematosus in India.
Anticardiolipin antibody (aCL) screening using an ELISA technique, in 76 patients of Indian origin with systemic lupus erythematosus (SLE), showed aCL in 27.63 per cent of patients. This prevalence was much lower than that reported in the Western population. The presence of aCL showed positive correlations with recurrent abortions and organic neurological lesions seen in SLE.
Saluja
S
S
Department of Medicine, All India Institute of Medical Sciences, New Delhi.
Kumar
A
A
Khamashta
M
M
Hughes
G R
GR
Malaviya
A N
AN
D000906:Antibodies / Q000032:analysis*; D002308:Cardiolipins / Q000009:adverse effects / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D008180:Lupus Erythematosus, Systemic / Q000453:epidemiology / Q000276:immunology*; D008297:Male; D015995:Prevalence; D013577:Syndrome
D000906:Antibodies; D002308:Cardiolipins