Involvement of cochlear nerve in acoustic tumours.
With conventional light and transmission electronmicroscopy we studied 10 cases of acoustic nerve tumour, 3 of which proved to be instances of von Recklinghausen neurofibroma and 7 of schwannoma. Schwannomas were not found to infiltrate the cochlear nerve. Hearing loss, if present in cases of schwannoma, could be related to non-specific lesions of the uninfiltrated cochlear nerve in the vicinity of the vestibular nerve tumour. Only neurofibromas were found to infiltrate the cochlear nerve. Distinction between tumour infiltration and non-specific lesion could be made by electron microscopy.
Perre
J
J
Laboratoire de Neurohistologie, Ecole Pratique des Hautes Etudes et Unité 106 INSERM, Hôpital de la Salpêtrière, Paris, France.
Viala
P
P
Foncin
J F
JF
D000293:Adolescent; D000328:Adult; D000368:Aged; D003056:Cochlear Nerve / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000473:pathology* / Q000648:ultrastructure