Thrombotic thrombocytopenic purpura. Clinical course and response to therapy in seven patients.
The clinical characteristics, treatment and outcome are reported in 7 patients with 8 episodes of thrombotic thrombocytopenic purpura (TTP). In all episodes a complete remission was reached. Plasma exchange therapy was successful as single treatment in two episodes. Combination with other treatment modalities, however, was necessary in six episodes, in which a complete hematologic and clinical remission was obtained with antiplatelet therapy (4 X), and with antiplatelet therapy and corticosteroids (2 X).
Vlot
A J
AJ
Department of Hematology, University Hospital, Utrecht, The Netherlands.
Hené
R J
RJ
Marx
J J
JJ
D000328:Adult; D005260:Female; D006801:Humans; D008875:Middle Aged; D011697:Purpura, Thrombotic Thrombocytopenic / Q000628:therapy*