title: Chordal replacement in mitral valve repair.
abstract: Chordal replacement greatly extends the possibility of repair of atrioventricular valves. Both glutaraldehyde-tanned xenograft pericardial chordae (GTXP) and extruded polytetrafluorethylene chordae (ePTFE) heal to papillary muscles and cusps. Neither type elongates or shrinks. GTXP may thicken and stiffen with time. ePTFE is covered by a normal fibrosa and intima (a new chorda is grown around the ePTFE suture) experimentally and in small sizes (e.g., CV 5), retains flexibility. The results of late follow-up (5-10 years) with GTXP chordae and early follow-up (6-58 months) with ePTFE chordae are encouraging.
authors.affiliation: Division of Cardiothoracic Surgery, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY.
authors.forename: R W
authors.initials: RW
authors.lastname: Frater
authors.forename: H O
authors.initials: HO
authors.lastname: Vetter
authors.forename: C
authors.initials: C
authors.lastname: Zussa
authors.forename: M
authors.initials: M
authors.lastname: Dahm
mesh_terms: D000328:Adult; D000368:Aged; D002815:Chordae Tendineae / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D010210:Papillary Muscles / Q000601:surgery; D010496:Pericardium; D011138:Polytetrafluoroethylene; D019736:Prostheses and Implants; D013536:Suture Techniques; D013997:Time Factors
chemical_list: D011138:Polytetrafluoroethylene