Lipoproteins and atherogenesis. Current concepts.
The frontiers in atherosclerosis research are moving from lipoprotein metabolism and control of hyperlipidemia to the cellular events in the artery wall. Emerging hypotheses, including the oxidative modification hypothesis, are already suggesting new approaches that could complement and be additive to control of hypercholesterolemia in the prevention of atherosclerosis.
Steinberg
D
D
Department of Medicine, University of California-San Diego, La Jolla 92093.
Witztum
J L
JL
D001161:Arteriosclerosis / Q000097:blood / Q000209:etiology* / Q000473:pathology; D008078:Cholesterol, LDL / Q000097:blood; D015243:Cholesterol, VLDL / Q000097:blood; D006801:Humans; D008074:Lipoproteins / Q000097:blood*
D008078:Cholesterol, LDL; D015243:Cholesterol, VLDL; D008074:Lipoproteins