[Increase in free Ca2+ level determined by quin-2 in spleen lymphocytes from irradiated rats].
The output of lymphocytes, obtained on a ficoll-verografin gradient and intracellular free Ca2+ concentration were studied in the rat spleen 1, 3 and 6 days after X-ray irradiation in a dose of 0.5 Gy. The amount of lymphocytes decreased by 30% a day after irradiation and turned to the control level 3 days after exposure of animals. Free Ca2+ concentration remains abnormally high during all the examined period, increasing to 411 nM a day after irradiation and approaching to the control value 6 days after irradiation.
Ruchko
M V
MV
Slatvinskaia
E A
EA
Matyshevskaia
O P
OP
Kucherenko
N E
NE
D000634:Aminoquinolines; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D005456:Fluorescent Dyes; D008214:Lymphocytes / Q000378:metabolism* / Q000528:radiation effects; D051381:Rats; D011919:Rats, Inbred Strains; D013154:Spleen / Q000166:cytology / Q000378:metabolism* / Q000528:radiation effects; D013997:Time Factors; D014916:Whole-Body Irradiation
D000634:Aminoquinolines; D005456:Fluorescent Dyes; C035739:Quin2; D002118:Calcium
Uvelichenie kontsentratsii svobodnogo Ca2+, opredelennoĭ s pomoshch'iu kvina-2 v limfotsitakh selezenki obluchennykh krys.