[Preliminary administration of perfluorocarbon emulsion: a new method of myocardial protection against ischemia].
The study was conducted to determine if myocardium can be protected against ischemic and reperfusion damage by means of the preliminarily injected perfluorocarbon emulsion. Injection of the emulsion into rabbit 1, 12, 24 h prior to ischemia was found to decrease the extent of ischemic and reperfusion damage to myocardium. The cardiotropic effect of the injected emulsion is shown to be dose- and time dependent.
Vorob'ev
S I
SI
Ladilov
Iu V
IuV
Obraztsov
V V
VV
Ivanitskiĭ
G R
GR
D000818:Animals; D004655:Emulsions; D005466:Fluorocarbons / Q000008:administration & dosage / Q000097:blood / Q000494:pharmacology*; D006321:Heart / Q000187:drug effects; D066298:In Vitro Techniques; D009200:Myocardial Contraction; D015428:Myocardial Reperfusion Injury / Q000517:prevention & control*; D009206:Myocardium / Q000166:cytology; D011817:Rabbits; D013053:Spectrophotometry; D013997:Time Factors
D004655:Emulsions; D005466:Fluorocarbons
Predvaritel'noe vvedenie émul'sii perftoruglerodov--novyĭ metod protivoishemicheskoĭ zashchity miokarda.