[The study on the specific eruptions of malignant lymphoma. II. Clinical and pathological interesting points, electron microscopic study, immune state and treatment].
We investigated 31 cases of cutaneous malignant lymphoma diagnosed by skin biopsy during about 11 years at the University of Tsukuba hospital. The interesting points are the followings; the difference of cell morphology between the primary lesion and the secondary skin lesion was found in one case diagnosed of Lennert's lymphoma. The erythrophagocytosis of tumor cells was found at the relapse of one case of TCL. Eosinophils were increased in number in accordance with the severity in a case of MF. The electron microscopic study revealed the LC approaching to the tumor cells in ATL and MF, and TRS in ATL. Group A maintained better immunity of PPD and DNCB skin test than Group B. Non-specific eruptions in Group A were found frequently at the late stage, about half of which were cutaneous/mucous fungous infection. In the treatment of Group A, soft X-ray therapy was an excellent method at the point of the responsiveness, the painlessness, the interval of relapse and side effects.
Iijima
S
S
Department of Dermatology, University of Tsukuba.
D000368:Aged; D000369:Aged, 80 and over; D004912:Erythrocytes / Q000473:pathology; D006801:Humans; D007111:Immunity, Cellular; D008223:Lymphoma / Q000276:immunology / Q000473:pathology* / Q000628:therapy; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D010587:Phagocytosis; D012867:Skin / Q000648:ultrastructure; D012878:Skin Neoplasms / Q000276:immunology / Q000473:pathology* / Q000628:therapy