title: Intravascular laser therapy of acute myocardial infarction.
abstract: The efficacy of a new method of treatment, endovascular blood irradiation with He-Ne laser, developed by the authors, was studied in 295 patients with primary acute transmural myocardial infarction (MI). Twenty-four-hour Holter monitoring findings before and after laser irradiation suggested the possibility of preventing sudden death in the acute period of MI owing to the high anti-arrhythmic efficacy of the method with respect to high-grade ventricular arrhythmias. Precodial ECG mapping and serial determination of blood enzyme activities (CPK and MB-CPK) showed that irradiation performed within the first hours of MI development contributed to effective limitation of the infarction area and restricted the spread of the area of myocardial ischemic damage.
authors.affiliation: Research Institute of Experimental and Clinical Therapy, Tbilisi, U.S.S.R.
authors.forename: N N
authors.initials: NN
authors.lastname: Kipshidze
authors.forename: G E
authors.initials: GE
authors.lastname: Chapidze
authors.forename: M R
authors.initials: MR
authors.lastname: Bokhua
authors.forename: L A
authors.initials: LA
authors.lastname: Marsagishvili
authors.forename: N K
authors.initials: NK
authors.lastname: Dolidze
authors.forename: D G
authors.initials: DG
authors.lastname: Eristavi
mesh_terms: D001145:Arrhythmias, Cardiac / Q000209:etiology / Q000517:prevention & control; D003402:Creatine Kinase / Q000097:blood; D015716:Electrocardiography, Ambulatory; D005260:Female; D006801:Humans; D007511:Ischemia / Q000517:prevention & control; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000150:complications / Q000601:surgery*
chemical_list: D003402:Creatine Kinase