title: [Diseases caused by Streptococcus pyogenes in Norway, 1975-1989. A microbiologic and epidemiologic survey].
abstract: The article briefly surveys the epidemiology of Streptococcus pyogenes caused disease in Norway during the last 15 years based on notification data, with emphasis on the nation-wide outbreak in 1987-88 caused by mucoid M-1 organisms. During the season S. pyogenes infections was 60% higher than expected. The number of bacteraemia cases, many with fulminant septicaemia, showed an almost threefold increase compared with earlier years. Unusual clinical manifestations such as necrotising fasciitis, pneumonia with empyema, primary peritonitis and meningitis also occurred. We briefly review the known virulence factors of S. pyogenes in an attempt to improve our understanding of the shift in clinical manifestations and occurrence of the disease.
authors.affiliation: Avdeling for bakteriologi, Statens institutt for folkehelse, Oslo.
authors.forename: E A
authors.initials: EA
authors.lastname: Høiby
authors.forename: P
authors.initials: P
authors.lastname: Gaustad
authors.forename: S
authors.initials: S
authors.lastname: Aasen
authors.forename: P R
authors.initials: PR
authors.lastname: Martin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D005208:Fasciitis / Q000382:microbiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008581:Meningitis / Q000382:microbiology; D008875:Middle Aged; D009664:Norway / Q000453:epidemiology; D010538:Peritonitis / Q000382:microbiology; D011014:Pneumonia / Q000382:microbiology; D018805:Sepsis / Q000382:microbiology; D013290:Streptococcal Infections / Q000453:epidemiology*; D013297:Streptococcus pyogenes / Q000145:classification
vernacular_title: Sykdom forårsaket av Streptococcus pyogenes i Norge 1975-89. En mikrobiologisk og epidemiologisk oversikt.