The regulatory control of hemopoietic populations.
The identification and mass-production by recombinant technology of twelve of the regulatory glycoproteins controlling hemopoiesis has represented a major advance in understanding hemopoiesis and introduces the possibility of being able to correct major disease states involving hemopoietic cells. Information so far on the control of megakaryocyte formation indicates that this follows the general pattern operating for other hemopoietic subpopulations and the present conference will review the new knowledge of specific factors influencing megakaryocyte formation and function.
Metcalf
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Walter and Eliza Hall Institute, Royal Melbourne Hospital, Victoria, Australia.
D000818:Animals; D002454:Cell Differentiation / Q000502:physiology; D003115:Colony-Stimulating Factors / Q000502:physiology; D006410:Hematopoiesis / Q000502:physiology*; D006801:Humans; D008533:Megakaryocytes / Q000166:cytology
D003115:Colony-Stimulating Factors