Effect of fluorine substitution on the anti-HIV activity of dideoxynucleosides.
Marquez
V E
VE
Laboratory of Medicinal Chemistry, National Cancer Institute, NIH, Bethesda, MD 20892.
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy*; D055598:Chemical Phenomena; D002621:Chemistry; D015224:Dideoxynucleosides / Q000138:chemical synthesis / Q000627:therapeutic use*; D015195:Drug Design; D005459:Fluorides / Q000138:chemical synthesis / Q000627:therapeutic use*; D011687:Purines / Q000138:chemical synthesis / Q000627:therapeutic use; D011743:Pyrimidines / Q000138:chemical synthesis / Q000627:therapeutic use; D013329:Structure-Activity Relationship
D015224:Dideoxynucleosides; D011687:Purines; D011743:Pyrimidines; D005459:Fluorides