[Hemostatic disorders in patients with Schoenlein-Henoch syndrome].
Several indices of coagulation and fibrinolysis were studied in 54 patients suffering from Schönlein-Henoch disease. A significant prolongation of platelet aggregation was found in parallel with a decrease of AT III and plasminogen and an increase of the fibrin monomer complexes. Consequent to heparin treatment controlled by measurements of residual thrombin activity, the indices showed a trend towards normalization. The dynamic monitoring of the above indices can be used for an overall assessment of the heparin treatment.
Mishkova
R
R
Kudeva
K
K
Petrova
E
E
D000328:Adult; D020152:Antithrombin III Deficiency; D005260:Female; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D011695:IgA Vasculitis / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010958:Plasminogen / Q000172:deficiency*; D010974:Platelet Aggregation / Q000187:drug effects / Q000502:physiology*; D013927:Thrombosis / Q000517:prevention & control
D010958:Plasminogen; D006493:Heparin
Narusheniia v sisteme svertyvaniia krovi u bol'nykh bolezn'iu Shenleĭna-Genokha.