title: [The liver-protective properties of D-glucosamine].
abstract: The antioxidant and membrane-stabilizing activities of D-glucosamine were studied on two models of toxic liver damage. When administered in a dose of 50 mg/kg, D-glucosamine was found to prevent the development of the hepatocyte cytolysis syndrome, to normalize the cholate- and glycogen-synthetic functions of the liver. D-glucosamine exhibited a significant anabolic effect that also supplemented its hepatoprotective activity.
authors.forename: S I
authors.initials: SI
authors.lastname: Sal'nikova
authors.forename: S M
authors.initials: SM
authors.lastname: Drogovoz
authors.forename: I A
authors.initials: IA
authors.lastname: Zupanets
mesh_terms: D000818:Animals; D000975:Antioxidants; D002252:Carbon Tetrachloride Poisoning / Q000188:drug therapy / Q000503:physiopathology; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy / Q000209:etiology / Q000503:physiopathology; D004353:Drug Evaluation, Preclinical; D000431:Ethanol; D005260:Female; D005944:Glucosamine / Q000627:therapeutic use*; D008099:Liver / Q000187:drug effects* / Q000503:physiopathology; D008297:Male; D051381:Rats; D011919:Rats, Inbred Strains
chemical_list: D000975:Antioxidants; D000431:Ethanol; D005944:Glucosamine
vernacular_title: Gepatozashchitnye svoĭstva D-gliukozamina.