title: [Shock wave lithotripsy of gallbladder stones: the initial 54 patients treated in Rotterdam-Dijkzigt].
abstract: From April 1988 till May 1990 54 patients with symptomatic gallbladder stones were treated in the University Hospital Rotterdam-Dijkzigt with extracorporeal shock wave lithotripsy (ESWL) followed by oral administration of bile acids (urso- and chenodeoxycholic acid). These patients on average underwent 2 sessions of ESWL with an electromagnetic lithotriptor (Lithostar and Lithostar Plus, Siemens AG, Erlangen, FRG). Ultimate disintegration of stones was achieved in 50/54 (93%) patients. The best results were achieved in patients with a solitary gallstone (56% of these patients were stone-free 12 months after ESWL). Four per cent of the patients with 2-10 stones were free of stones 12 months after ESWL). Thirty-seven per cent of the patients suffered from biliary colics after ESWL and three patients developed pancreatitis. The administration of oral bile acids were complicated by transient diarrhoea in 20% of the patients. ESWL followed by oral bile acid therapy is a relatively effective and safe therapy for a highly selected population of patients with gallbladder stones.
authors.affiliation: Afd. Heelkunde, Academisch Ziekenhuis Rotterdam-Dijkzigt, Rotterdam.
authors.forename: R
authors.initials: R
authors.lastname: den Toom
authors.forename: H
authors.initials: H
authors.lastname: Vergunst
authors.forename: H G
authors.initials: HG
authors.lastname: Nijs
authors.forename: K
authors.initials: K
authors.lastname: Brakel
authors.forename: J S
authors.initials: JS
authors.lastname: Laméris
authors.forename: O T
authors.initials: OT
authors.lastname: Terpstra
mesh_terms: D000328:Adult; D000368:Aged; D002635:Chenodeoxycholic Acid / Q000627:therapeutic use; D002769:Cholelithiasis / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008096:Lithotripsy; D008297:Male; D008875:Middle Aged; D014580:Ursodeoxycholic Acid / Q000627:therapeutic use
chemical_list: D002635:Chenodeoxycholic Acid; D014580:Ursodeoxycholic Acid
vernacular_title: Schokgolfvergruizing van stenen in de galblaas; de eerste 54 in Rotterdam-Dijkzigt behandelde patiënten.