A fatal case of low titer anti-PR cold agglutinin disease.
Cold agglutinin disease typically produces a low-grade hemolytic anemia. We describe herein the unusual occurrence of an anti-PR cold agglutinin with high thermal amplitude which caused significant and ultimately fatal hemolytic anemia at very low titers.
Rousey
S R
SR
Department of Medicine, Medical College of Wisconsin, Milwaukee.
Smith
R E
RE
D000368:Aged; D000373:Agglutinins / Q000032:analysis; D000744:Anemia, Hemolytic, Autoimmune / Q000503:physiopathology*; D003450:Cryoglobulins; D005260:Female; D006801:Humans
D000373:Agglutinins; D003450:Cryoglobulins; C029443:cold agglutinins