Massive mediastinal extramedullary hematopoiesis in hereditary spherocytosis: a case report.
A case of extramedullary hematopoiesis (EMH) with a massive mediastinal mass in a 72-year-old woman with hereditary spherocytosis is reported. Several cases of EMH have been described in nonsplenectomized adults with hereditary spherocytosis, and it is thought to be a consequence of long-term stimulation of erythropoiesis. The exact mechanism remains controversial. EMH should be considered in the differential diagnosis of an asymptomatic paravertebral mass.
Bastion
Y
Y
Hematology Service, Centre Hospitalier Lyon-Sud, Pierre-Benite, France.
Coiffier
B
B
Felman
P
P
Assouline
D
D
Tigaud
J D
JD
Espinouse
D
D
Bryon
P A
PA
D000368:Aged; D005260:Female; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D013103:Spherocytosis, Hereditary / Q000097:blood* / Q000503:physiopathology