[The results of multiyear observations on the duration of the maintenance of immunity in those vaccinated and revaccinated against and recovered from measles].
The results of 5-year observations on the duration of immunity to measles virus in persons vaccinated and revaccinated against measles, as well as in persons having had this infection, are presented. The intensity of immunity was determined in the same persons with the use of the passive hemagglutination test. The study revealed differences in the formation, intensity and duration of postvaccinal immunity. A significant decrease in the concentration of antibodies over the period of 5 years was established in 50.0-52.3% of vaccines. Revaccination with live measles vaccine is an effective measure for enhancing immunity to measles virus in persons with initial antibody titers less than 1:10-1:20, but revaccination made in a single injection is not sufficient for the stable maintenance of measles morbidity at the sporadic level. Postinfectious immunity is characterized by stability and has no tendency towards decrease. Persons having had measles have no need in additional measures irrespective of the time elapsed after the disease.
Sliusar'
L I
LI
Sokhin
A A
AA
Radomskaia
F S
FS
Degtiareva
G V
GV
Panasenko
L I
LI
Litvinova
T P
TP
Komarevskaia
R V
RV
Bol'shinskaia
Zh I
ZhI
D000914:Antibodies, Viral / Q000097:blood; D000917:Antibody Formation; D002648:Child; D003289:Convalescence; D006801:Humans; D007117:Immunization, Secondary; D008457:Measles / Q000276:immunology* / Q000517:prevention & control; D008458:Measles Vaccine / Q000276:immunology*; D008459:Measles virus / Q000276:immunology; D013997:Time Factors; D014455:Ukraine; D014505:Urban Population
D000914:Antibodies, Viral; D008458:Measles Vaccine
Rezul'taty mnogoletnikh nabliudeniĭ za dlitel'nost'iu sokhraneniia immuniteta u vaktsinirovannykh, revaktsinirovannykh i perebolevshikh kor'iu.