Nutritional stress proteins in Candida albicans.
Starving cells of Candida albicans synthesize at least seven proteins that represent nutritional-stress proteins (NSP). Such NSPs are formed by both germination-competent and germination-deficient strains of C. albicans. Heat-shock proteins (HSP) are not formed by starving cells. Germination-competent cells synthesize specific sets of proteins when incubated in a starvation medium that contains the germ-tube-inducing substances N-acetyl-D-glucosamine or L-proline. Both sets of induced proteins were also synthesized by a germination-deficient strain of C. albicans.
Dabrowa
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Department of Microbiology and Immunology, UCLA School of Medicine 90024.
Zeuthen
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Howard
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D000117:Acetylglucosamine / Q000378:metabolism; D002176:Candida albicans / Q000254:growth & development* / Q000378:metabolism; D004591:Electrophoresis, Polyacrylamide Gel; D005656:Fungal Proteins / Q000096:biosynthesis* / Q000378:metabolism; D006360:Heat-Shock Proteins / Q000096:biosynthesis; D011392:Proline / Q000378:metabolism
D005656:Fungal Proteins; D006360:Heat-Shock Proteins; D011392:Proline; D000117:Acetylglucosamine